id	sid	tid	token	lemma	pos
dpc-4685	1	1	dermatology	dermatology	NOUN
dpc-4685	1	2	:	:	PUNCT
dpc-4685	1	3	practical	practical	ADJ
dpc-4685	1	4	and	and	CCONJ
dpc-4685	1	5	conceptual	conceptual	ADJ
dpc-4685	1	6	research	research	NOUN
dpc-4685	1	7	letter	letter	NOUN
dpc-4685	2	1	|	|	ADV
dpc-4685	2	2	dermatol	dermatol	ADJ
dpc-4685	2	3	pract	pract	NOUN
dpc-4685	2	4	concept	concept	NOUN
dpc-4685	2	5	.	.	PUNCT
dpc-4685	3	1	2025;15(1):4685	2025;15(1):4685	NUM
dpc-4685	3	2	1	1	NUM
dpc-4685	3	3	refractory	refractory	NOUN
dpc-4685	3	4	chronic	chronic	ADJ
dpc-4685	3	5	hand	hand	NOUN
dpc-4685	3	6	eczema	eczema	NOUN
dpc-4685	3	7	responds	respond	VERB
dpc-4685	3	8	to	to	ADP
dpc-4685	3	9	oral	oral	ADJ
dpc-4685	3	10	upadacitinib	upadacitinib	NOUN
dpc-4685	3	11	nada	nada	PROPN
dpc-4685	3	12	j.	j.	PROPN
dpc-4685	3	13	alghamdi1	alghamdi1	PROPN
dpc-4685	3	14	,	,	PUNCT
dpc-4685	3	15	abdullah	abdullah	PROPN
dpc-4685	3	16	a.	a.	NOUN
dpc-4685	3	17	aljalfan1	aljalfan1	PROPN
dpc-4685	3	18	,	,	PUNCT
dpc-4685	3	19	abdulmajeed	abdulmajeed	PROPN
dpc-4685	3	20	s.	s.	PROPN
dpc-4685	3	21	alharbi2	alharbi2	PROPN
dpc-4685	3	22	,	,	PUNCT
dpc-4685	3	23	omar	omar	PROPN
dpc-4685	3	24	i.	i.	PROPN
dpc-4685	3	25	alrubaish2	alrubaish2	PROPN
dpc-4685	3	26	,	,	PUNCT
dpc-4685	3	27	serene	serene	PROPN
dpc-4685	3	28	r.	r.	PROPN
dpc-4685	3	29	almuhaidib3	almuhaidib3	PROPN
dpc-4685	4	1	1	1	NUM
dpc-4685	4	2	department	department	NOUN
dpc-4685	4	3	of	of	ADP
dpc-4685	4	4	dermatology	dermatology	NOUN
dpc-4685	4	5	,	,	PUNCT
dpc-4685	4	6	king	king	PROPN
dpc-4685	4	7	fahd	fahd	PROPN
dpc-4685	4	8	university	university	PROPN
dpc-4685	4	9	hospital	hospital	NOUN
dpc-4685	4	10	,	,	PUNCT
dpc-4685	4	11	al	al	PROPN
dpc-4685	4	12	khobar	khobar	PROPN
dpc-4685	4	13	,	,	PUNCT
dpc-4685	4	14	saudi	saudi	PROPN
dpc-4685	4	15	arabia	arabia	PROPN
dpc-4685	4	16	2	2	NUM
dpc-4685	4	17	college	college	NOUN
dpc-4685	4	18	of	of	ADP
dpc-4685	4	19	medicine	medicine	NOUN
dpc-4685	4	20	,	,	PUNCT
dpc-4685	4	21	imam	imam	PROPN
dpc-4685	4	22	abdulrahman	abdulrahman	PROPN
dpc-4685	4	23	bin	bin	PROPN
dpc-4685	4	24	faisal	faisal	PROPN
dpc-4685	4	25	university	university	PROPN
dpc-4685	4	26	,	,	PUNCT
dpc-4685	4	27	dammam	dammam	PROPN
dpc-4685	4	28	,	,	PUNCT
dpc-4685	4	29	saudi	saudi	PROPN
dpc-4685	4	30	arabia	arabia	PROPN
dpc-4685	4	31	3	3	NUM
dpc-4685	4	32	dammam	dammam	PROPN
dpc-4685	4	33	medical	medical	ADJ
dpc-4685	4	34	complex	complex	ADJ
dpc-4685	4	35	hospital	hospital	NOUN
dpc-4685	4	36	,	,	PUNCT
dpc-4685	4	37	dammam	dammam	PROPN
dpc-4685	4	38	,	,	PUNCT
dpc-4685	4	39	saudi	saudi	PROPN
dpc-4685	4	40	arabia	arabia	PROPN
dpc-4685	4	41	key	key	ADJ
dpc-4685	4	42	words	word	NOUN
dpc-4685	4	43	:	:	PUNCT
dpc-4685	4	44	hand	hand	NOUN
dpc-4685	4	45	eczema	eczema	NOUN
dpc-4685	4	46	,	,	PUNCT
dpc-4685	4	47	upadacitinib	upadacitinib	NOUN
dpc-4685	4	48	,	,	PUNCT
dpc-4685	4	49	dermatitis	dermatitis	PROPN
dpc-4685	4	50	,	,	PUNCT
dpc-4685	4	51	jak	jak	PROPN
dpc-4685	4	52	inhibitor	inhibitor	PROPN
dpc-4685	4	53	citation	citation	NOUN
dpc-4685	4	54	:	:	PUNCT
dpc-4685	4	55	alghamdi	alghamdi	PROPN
dpc-4685	4	56	nj	nj	PROPN
dpc-4685	4	57	,	,	PUNCT
dpc-4685	4	58	aljalfan	aljalfan	NOUN
dpc-4685	4	59	aa	aa	NOUN
dpc-4685	4	60	,	,	PUNCT
dpc-4685	4	61	alharbi	alharbi	ADJ
dpc-4685	4	62	as	as	ADP
dpc-4685	4	63	,	,	PUNCT
dpc-4685	4	64	alrubaish	alrubaish	NOUN
dpc-4685	4	65	oi	oi	PROPN
dpc-4685	4	66	,	,	PUNCT
dpc-4685	4	67	almuhaidib	almuhaidib	VERB
dpc-4685	4	68	sr	sr	PROPN
dpc-4685	4	69	.	.	PUNCT
dpc-4685	5	1	refractory	refractory	PROPN
dpc-4685	5	2	chronic	chronic	ADJ
dpc-4685	5	3	hand	hand	NOUN
dpc-4685	5	4	eczema	eczema	NOUN
dpc-4685	5	5	responds	respond	VERB
dpc-4685	5	6	to	to	ADP
dpc-4685	5	7	oral	oral	ADJ
dpc-4685	5	8	upadacitinib	upadacitinib	NOUN
dpc-4685	5	9	.	.	PUNCT
dpc-4685	6	1	dermatol	dermatol	NOUN
dpc-4685	6	2	pract	pract	PROPN
dpc-4685	6	3	concept	concept	NOUN
dpc-4685	6	4	.	.	PUNCT
dpc-4685	7	1	2025;15(1):4685	2025;15(1):4685	X
dpc-4685	7	2	.	.	PUNCT
dpc-4685	7	3	doi	doi	PROPN
dpc-4685	7	4	:	:	PUNCT
dpc-4685	7	5	https://doi.org/10.5826/dpc.1501a4685	https://doi.org/10.5826/dpc.1501a4685	PROPN
dpc-4685	7	6	accepted	accept	VERB
dpc-4685	7	7	:	:	PUNCT
dpc-4685	7	8	october	october	PROPN
dpc-4685	7	9	2	2	NUM
dpc-4685	7	10	,	,	PUNCT
dpc-4685	7	11	2024	2024	NUM
dpc-4685	7	12	;	;	PUNCT
dpc-4685	7	13	published	publish	VERB
dpc-4685	7	14	:	:	PUNCT
dpc-4685	8	1	january	january	PROPN
dpc-4685	8	2	2025	2025	NUM
dpc-4685	8	3	copyright	copyright	NOUN
dpc-4685	8	4	:	:	PUNCT
dpc-4685	8	5	©	©	PROPN
dpc-4685	8	6	2024	2024	NUM
dpc-4685	8	7	alghamdi	alghamdi	NOUN
dpc-4685	8	8	et	et	PROPN
dpc-4685	8	9	al	al	PROPN
dpc-4685	8	10	.	.	PUNCT
dpc-4685	9	1	this	this	PRON
dpc-4685	9	2	is	be	AUX
dpc-4685	9	3	an	an	DET
dpc-4685	9	4	open	open	ADJ
dpc-4685	9	5	-	-	PUNCT
dpc-4685	9	6	access	access	NOUN
dpc-4685	9	7	article	article	NOUN
dpc-4685	9	8	distributed	distribute	VERB
dpc-4685	9	9	under	under	ADP
dpc-4685	9	10	the	the	DET
dpc-4685	9	11	terms	term	NOUN
dpc-4685	9	12	of	of	ADP
dpc-4685	9	13	the	the	DET
dpc-4685	9	14	creative	creative	ADJ
dpc-4685	9	15	commons	common	NOUN
dpc-4685	9	16	attributionnoncommercial	attributionnoncommercial	ADJ
dpc-4685	9	17	license	license	NOUN
dpc-4685	9	18	(	(	PUNCT
dpc-4685	9	19	by	by	ADP
dpc-4685	9	20	-	-	PUNCT
dpc-4685	9	21	nc-4.0	nc-4.0	NOUN
dpc-4685	9	22	)	)	PUNCT
dpc-4685	9	23	,	,	PUNCT
dpc-4685	9	24	https://creativecommons.org/licenses/by-nc/4.0/	https://creativecommons.org/licenses/by-nc/4.0/	PROPN
dpc-4685	9	25	,	,	PUNCT
dpc-4685	9	26	which	which	PRON
dpc-4685	9	27	permits	permit	VERB
dpc-4685	9	28	unrestricted	unrestricted	ADJ
dpc-4685	9	29	noncommercial	noncommercial	ADJ
dpc-4685	9	30	use	use	NOUN
dpc-4685	9	31	,	,	PUNCT
dpc-4685	9	32	distribution	distribution	NOUN
dpc-4685	9	33	,	,	PUNCT
dpc-4685	9	34	and	and	CCONJ
dpc-4685	9	35	reproduction	reproduction	NOUN
dpc-4685	9	36	in	in	ADP
dpc-4685	9	37	any	any	DET
dpc-4685	9	38	medium	medium	NOUN
dpc-4685	9	39	,	,	PUNCT
dpc-4685	9	40	provided	provide	VERB
dpc-4685	9	41	the	the	DET
dpc-4685	9	42	original	original	ADJ
dpc-4685	9	43	authors	author	NOUN
dpc-4685	9	44	and	and	CCONJ
dpc-4685	9	45	source	source	NOUN
dpc-4685	9	46	are	be	AUX
dpc-4685	9	47	credited	credit	VERB
dpc-4685	9	48	.	.	PUNCT
dpc-4685	10	1	funding	funding	NOUN
dpc-4685	10	2	:	:	PUNCT
dpc-4685	10	3	none	none	NOUN
dpc-4685	10	4	.	.	PUNCT
dpc-4685	11	1	competing	compete	VERB
dpc-4685	11	2	interests	interest	NOUN
dpc-4685	11	3	:	:	PUNCT
dpc-4685	11	4	none	none	NOUN
dpc-4685	11	5	.	.	PUNCT
dpc-4685	12	1	authorship	authorship	NOUN
dpc-4685	12	2	:	:	PUNCT
dpc-4685	12	3	all	all	DET
dpc-4685	12	4	authors	author	NOUN
dpc-4685	12	5	have	have	AUX
dpc-4685	12	6	contributed	contribute	VERB
dpc-4685	12	7	significantly	significantly	ADV
dpc-4685	12	8	to	to	ADP
dpc-4685	12	9	this	this	DET
dpc-4685	12	10	publication	publication	NOUN
dpc-4685	12	11	.	.	PUNCT
dpc-4685	13	1	corresponding	correspond	VERB
dpc-4685	13	2	author	author	NOUN
dpc-4685	13	3	:	:	PUNCT
dpc-4685	13	4	abdullah	abdullah	PROPN
dpc-4685	13	5	ali	ali	PROPN
dpc-4685	13	6	aljalfan	aljalfan	PROPN
dpc-4685	13	7	,	,	PUNCT
dpc-4685	13	8	md	md	PROPN
dpc-4685	13	9	,	,	PUNCT
dpc-4685	13	10	department	department	PROPN
dpc-4685	13	11	of	of	ADP
dpc-4685	13	12	dermatology	dermatology	NOUN
dpc-4685	13	13	,	,	PUNCT
dpc-4685	13	14	king	king	PROPN
dpc-4685	13	15	fahd	fahd	PROPN
dpc-4685	13	16	university	university	PROPN
dpc-4685	13	17	hospital	hospital	NOUN
dpc-4685	13	18	,	,	PUNCT
dpc-4685	13	19	address	address	NOUN
dpc-4685	13	20	:	:	PUNCT
dpc-4685	13	21	p.o	p.o	PROPN
dpc-4685	13	22	.	.	PROPN
dpc-4685	13	23	box	box	PROPN
dpc-4685	13	24	34246	34246	NUM
dpc-4685	13	25	,	,	PUNCT
dpc-4685	13	26	al	al	PROPN
dpc-4685	13	27	khobar	khobar	PROPN
dpc-4685	13	28	,	,	PUNCT
dpc-4685	13	29	saudi	saudi	PROPN
dpc-4685	13	30	arabia	arabia	PROPN
dpc-4685	13	31	.	.	PUNCT
dpc-4685	14	1	phone	phone	NOUN
dpc-4685	14	2	:	:	PUNCT
dpc-4685	14	3	+966558744844	+966558744844	NUM
dpc-4685	14	4	.	.	PUNCT
dpc-4685	15	1	e	e	X
dpc-4685	15	2	-	-	NOUN
dpc-4685	15	3	mail	mail	NOUN
dpc-4685	15	4	:	:	PUNCT
dpc-4685	15	5	a.jalfan7@hotmail.com	a.jalfan7@hotmail.com	PROPN
dpc-4685	15	6	introduction	introduction	NOUN
dpc-4685	15	7	hand	hand	NOUN
dpc-4685	15	8	dermatitis	dermatitis	NOUN
dpc-4685	15	9	is	be	AUX
dpc-4685	15	10	a	a	DET
dpc-4685	15	11	common	common	ADJ
dpc-4685	15	12	inflammatory	inflammatory	ADJ
dpc-4685	15	13	skin	skin	NOUN
dpc-4685	15	14	condition	condition	NOUN
dpc-4685	15	15	that	that	PRON
dpc-4685	15	16	greatly	greatly	ADV
dpc-4685	15	17	affects	affect	VERB
dpc-4685	15	18	quality	quality	NOUN
dpc-4685	15	19	of	of	ADP
dpc-4685	15	20	life	life	NOUN
dpc-4685	15	21	and	and	CCONJ
dpc-4685	15	22	productivity	productivity	NOUN
dpc-4685	15	23	.	.	PUNCT
dpc-4685	16	1	it	it	PRON
dpc-4685	16	2	can	can	AUX
dpc-4685	16	3	be	be	AUX
dpc-4685	16	4	caused	cause	VERB
dpc-4685	16	5	by	by	ADP
dpc-4685	16	6	endogenous	endogenous	ADJ
dpc-4685	16	7	causes	cause	NOUN
dpc-4685	16	8	like	like	ADP
dpc-4685	16	9	atopic	atopic	NOUN
dpc-4685	16	10	dermatitis	dermatitis	NOUN
dpc-4685	16	11	,	,	PUNCT
dpc-4685	16	12	or	or	CCONJ
dpc-4685	16	13	exogenous	exogenous	ADJ
dpc-4685	16	14	causes	cause	NOUN
dpc-4685	16	15	like	like	ADP
dpc-4685	16	16	contact	contact	NOUN
dpc-4685	16	17	dermatitis	dermatitis	NOUN
dpc-4685	16	18	either	either	CCONJ
dpc-4685	16	19	irritant	irritant	ADJ
dpc-4685	16	20	or	or	CCONJ
dpc-4685	16	21	allergic	allergic	ADJ
dpc-4685	17	1	[	[	X
dpc-4685	17	2	1	1	NUM
dpc-4685	17	3	]	]	PUNCT
dpc-4685	17	4	.	.	PUNCT
dpc-4685	18	1	treatment	treatment	NOUN
dpc-4685	18	2	options	option	NOUN
dpc-4685	18	3	for	for	ADP
dpc-4685	18	4	hand	hand	NOUN
dpc-4685	18	5	dermatitis	dermatitis	NOUN
dpc-4685	18	6	include	include	VERB
dpc-4685	18	7	topical	topical	ADJ
dpc-4685	18	8	and	and	CCONJ
dpc-4685	18	9	oral	oral	ADJ
dpc-4685	18	10	medication	medication	NOUN
dpc-4685	18	11	,	,	PUNCT
dpc-4685	18	12	phototherapy	phototherapy	NOUN
dpc-4685	18	13	.	.	PUNCT
dpc-4685	19	1	however	however	ADV
dpc-4685	19	2	,	,	PUNCT
dpc-4685	19	3	severe	severe	ADJ
dpc-4685	19	4	and	and	CCONJ
dpc-4685	19	5	difficult	difficult	ADJ
dpc-4685	19	6	-	-	PUNCT
dpc-4685	19	7	to	to	ADP
dpc-4685	19	8	-	-	PUNCT
dpc-4685	19	9	treat	treat	NOUN
dpc-4685	19	10	cases	case	NOUN
dpc-4685	19	11	,	,	PUNCT
dpc-4685	19	12	particularly	particularly	ADV
dpc-4685	19	13	those	those	PRON
dpc-4685	19	14	not	not	PART
dpc-4685	19	15	associated	associate	VERB
dpc-4685	19	16	with	with	ADP
dpc-4685	19	17	atopic	atopic	NOUN
dpc-4685	19	18	dermatitis	dermatitis	NOUN
dpc-4685	19	19	,	,	PUNCT
dpc-4685	19	20	have	have	VERB
dpc-4685	19	21	limited	limit	VERB
dpc-4685	19	22	treatment	treatment	NOUN
dpc-4685	19	23	choices	choice	NOUN
dpc-4685	19	24	[	[	X
dpc-4685	19	25	2,3	2,3	NUM
dpc-4685	19	26	]	]	PUNCT
dpc-4685	19	27	.	.	PUNCT
dpc-4685	20	1	research	research	NOUN
dpc-4685	20	2	is	be	AUX
dpc-4685	20	3	ongoing	ongoing	ADJ
dpc-4685	20	4	to	to	PART
dpc-4685	20	5	explore	explore	VERB
dpc-4685	20	6	the	the	DET
dpc-4685	20	7	use	use	NOUN
dpc-4685	20	8	of	of	ADP
dpc-4685	20	9	immunomodulatory	immunomodulatory	ADJ
dpc-4685	20	10	drugs	drug	NOUN
dpc-4685	20	11	,	,	PUNCT
dpc-4685	20	12	like	like	ADP
dpc-4685	20	13	janus	janus	PROPN
dpc-4685	20	14	kinase	kinase	PROPN
dpc-4685	20	15	(	(	PUNCT
dpc-4685	20	16	jak	jak	PROPN
dpc-4685	20	17	)	)	PUNCT
dpc-4685	20	18	inhibitors	inhibitor	NOUN
dpc-4685	20	19	,	,	PUNCT
dpc-4685	20	20	for	for	ADP
dpc-4685	20	21	chronic	chronic	ADJ
dpc-4685	20	22	hand	hand	NOUN
dpc-4685	20	23	eczema	eczema	NOUN
dpc-4685	21	1	[	[	X
dpc-4685	21	2	2	2	NUM
dpc-4685	21	3	]	]	PUNCT
dpc-4685	21	4	.	.	PUNCT
dpc-4685	22	1	case	case	NOUN
dpc-4685	22	2	presentation	presentation	NOUN
dpc-4685	22	3	a	a	DET
dpc-4685	22	4	58	58	NUM
dpc-4685	22	5	-	-	PUNCT
dpc-4685	22	6	year	year	NOUN
dpc-4685	22	7	-	-	PUNCT
dpc-4685	22	8	old	old	ADJ
dpc-4685	22	9	woman	woman	NOUN
dpc-4685	22	10	with	with	ADP
dpc-4685	22	11	a	a	DET
dpc-4685	22	12	history	history	NOUN
dpc-4685	22	13	of	of	ADP
dpc-4685	22	14	chronic	chronic	ADJ
dpc-4685	22	15	hand	hand	NOUN
dpc-4685	22	16	eczema	eczema	NOUN
dpc-4685	22	17	was	be	AUX
dpc-4685	22	18	referred	refer	VERB
dpc-4685	22	19	to	to	ADP
dpc-4685	22	20	our	our	PRON
dpc-4685	22	21	dermatology	dermatology	NOUN
dpc-4685	22	22	department	department	NOUN
dpc-4685	22	23	due	due	ADP
dpc-4685	22	24	to	to	ADP
dpc-4685	22	25	significant	significant	ADJ
dpc-4685	22	26	deterioration	deterioration	NOUN
dpc-4685	22	27	of	of	ADP
dpc-4685	22	28	her	her	PRON
dpc-4685	22	29	condition	condition	NOUN
dpc-4685	22	30	.	.	PUNCT
dpc-4685	23	1	this	this	DET
dpc-4685	23	2	deterioration	deterioration	NOUN
dpc-4685	23	3	was	be	AUX
dpc-4685	23	4	characterized	characterize	VERB
dpc-4685	23	5	by	by	ADP
dpc-4685	23	6	extreme	extreme	ADJ
dpc-4685	23	7	pruritus	pruritus	PROPN
dpc-4685	23	8	and	and	CCONJ
dpc-4685	23	9	severe	severe	ADJ
dpc-4685	23	10	dryness	dryness	NOUN
dpc-4685	23	11	primarily	primarily	ADV
dpc-4685	23	12	on	on	ADP
dpc-4685	23	13	the	the	DET
dpc-4685	23	14	palmar	palmar	NOUN
dpc-4685	23	15	surfaces	surface	NOUN
dpc-4685	23	16	of	of	ADP
dpc-4685	23	17	both	both	DET
dpc-4685	23	18	hands	hand	NOUN
dpc-4685	23	19	(	(	PUNCT
dpc-4685	23	20	figure	figure	NOUN
dpc-4685	23	21	1	1	NUM
dpc-4685	23	22	)	)	PUNCT
dpc-4685	23	23	.	.	PUNCT
dpc-4685	24	1	the	the	DET
dpc-4685	24	2	patient	patient	ADJ
dpc-4685	24	3	condition	condition	NOUN
dpc-4685	24	4	had	have	AUX
dpc-4685	24	5	worsened	worsen	VERB
dpc-4685	24	6	after	after	SCONJ
dpc-4685	24	7	the	the	DET
dpc-4685	24	8	covid-19	covid-19	PROPN
dpc-4685	24	9	pandemic	pandemic	NOUN
dpc-4685	24	10	started	start	VERB
dpc-4685	24	11	.	.	PUNCT
dpc-4685	25	1	she	she	PRON
dpc-4685	25	2	sought	seek	VERB
dpc-4685	25	3	medical	medical	ADJ
dpc-4685	25	4	intervention	intervention	NOUN
dpc-4685	25	5	following	follow	VERB
dpc-4685	25	6	the	the	DET
dpc-4685	25	7	intense	intense	ADJ
dpc-4685	25	8	exacerbation	exacerbation	NOUN
dpc-4685	25	9	.	.	PUNCT
dpc-4685	26	1	the	the	DET
dpc-4685	26	2	patient	patient	NOUN
dpc-4685	26	3	had	have	VERB
dpc-4685	26	4	neither	neither	CCONJ
dpc-4685	26	5	personal	personal	ADJ
dpc-4685	26	6	nor	nor	CCONJ
dpc-4685	26	7	familial	familial	ADJ
dpc-4685	26	8	history	history	NOUN
dpc-4685	26	9	of	of	ADP
dpc-4685	26	10	atopic	atopic	NOUN
dpc-4685	26	11	dermatitis	dermatitis	NOUN
dpc-4685	26	12	or	or	CCONJ
dpc-4685	26	13	other	other	ADJ
dpc-4685	26	14	form	form	NOUN
dpc-4685	26	15	of	of	ADP
dpc-4685	26	16	atopy	atopy	NOUN
dpc-4685	26	17	.	.	PUNCT
dpc-4685	27	1	several	several	ADJ
dpc-4685	27	2	diagnostic	diagnostic	ADJ
dpc-4685	27	3	procedures	procedure	NOUN
dpc-4685	27	4	were	be	AUX
dpc-4685	27	5	done	do	VERB
dpc-4685	27	6	,	,	PUNCT
dpc-4685	27	7	including	include	VERB
dpc-4685	27	8	a	a	DET
dpc-4685	27	9	patch	patch	NOUN
dpc-4685	27	10	test	test	NOUN
dpc-4685	27	11	,	,	PUNCT
dpc-4685	27	12	standard	standard	ADJ
dpc-4685	27	13	laboratory	laboratory	NOUN
dpc-4685	27	14	tests	test	NOUN
dpc-4685	27	15	and	and	CCONJ
dpc-4685	27	16	mycological	mycological	ADJ
dpc-4685	27	17	culture	culture	NOUN
dpc-4685	27	18	were	be	AUX
dpc-4685	27	19	negative	negative	ADJ
dpc-4685	27	20	.	.	PUNCT
dpc-4685	28	1	a	a	DET
dpc-4685	28	2	skin	skin	NOUN
dpc-4685	28	3	biopsy	biopsy	NOUN
dpc-4685	28	4	(	(	PUNCT
dpc-4685	28	5	performed	perform	VERB
dpc-4685	28	6	outside	outside	ADP
dpc-4685	28	7	our	our	PRON
dpc-4685	28	8	institution	institution	NOUN
dpc-4685	28	9	)	)	PUNCT
dpc-4685	28	10	revealed	reveal	VERB
dpc-4685	28	11	eczematous	eczematous	ADJ
dpc-4685	28	12	changes	change	NOUN
dpc-4685	28	13	.	.	PUNCT
dpc-4685	29	1	before	before	ADP
dpc-4685	29	2	coming	come	VERB
dpc-4685	29	3	to	to	ADP
dpc-4685	29	4	our	our	PRON
dpc-4685	29	5	clinic	clinic	NOUN
dpc-4685	29	6	,	,	PUNCT
dpc-4685	29	7	she	she	PRON
dpc-4685	29	8	had	have	AUX
dpc-4685	29	9	been	be	AUX
dpc-4685	29	10	treated	treat	VERB
dpc-4685	29	11	with	with	ADP
dpc-4685	29	12	a	a	DET
dpc-4685	29	13	variety	variety	NOUN
dpc-4685	29	14	of	of	ADP
dpc-4685	29	15	topical	topical	ADJ
dpc-4685	29	16	medications	medication	NOUN
dpc-4685	29	17	,	,	PUNCT
dpc-4685	29	18	including	include	VERB
dpc-4685	29	19	topical	topical	ADJ
dpc-4685	29	20	clobetasol	clobetasol	NOUN
dpc-4685	29	21	,	,	PUNCT
dpc-4685	29	22	topical	topical	ADJ
dpc-4685	29	23	tacrolimus	tacrolimus	NOUN
dpc-4685	29	24	,	,	PUNCT
dpc-4685	29	25	with	with	ADP
dpc-4685	29	26	little	little	ADJ
dpc-4685	29	27	or	or	CCONJ
dpc-4685	29	28	no	no	PRON
dpc-4685	29	29	relief	relief	NOUN
dpc-4685	29	30	.	.	PUNCT
dpc-4685	30	1	a	a	DET
dpc-4685	30	2	3	3	NUM
dpc-4685	30	3	-	-	PUNCT
dpc-4685	30	4	month	month	NOUN
dpc-4685	30	5	trial	trial	NOUN
dpc-4685	30	6	of	of	ADP
dpc-4685	30	7	nb	nb	NOUN
dpc-4685	30	8	-	-	ADJ
dpc-4685	30	9	uvb	uvb	ADJ
dpc-4685	30	10	phototherapy	phototherapy	NOUN
dpc-4685	30	11	was	be	AUX
dpc-4685	30	12	conducted	conduct	VERB
dpc-4685	30	13	3	3	NUM
dpc-4685	30	14	times	time	NOUN
dpc-4685	30	15	per	per	ADP
dpc-4685	30	16	week	week	NOUN
dpc-4685	30	17	.	.	PUNCT
dpc-4685	31	1	despite	despite	SCONJ
dpc-4685	31	2	this	this	DET
dpc-4685	31	3	treatment	treatment	NOUN
dpc-4685	31	4	regimen	regiman	NOUN
dpc-4685	31	5	,	,	PUNCT
dpc-4685	31	6	no	no	DET
dpc-4685	31	7	alleviation	alleviation	NOUN
dpc-4685	31	8	of	of	ADP
dpc-4685	31	9	itchiness	itchiness	NOUN
dpc-4685	31	10	was	be	AUX
dpc-4685	31	11	observed	observe	VERB
dpc-4685	31	12	,	,	PUNCT
dpc-4685	31	13	and	and	CCONJ
dpc-4685	31	14	the	the	DET
dpc-4685	31	15	lesions	lesion	NOUN
dpc-4685	31	16	remained	remain	VERB
dpc-4685	31	17	resilient	resilient	ADJ
dpc-4685	31	18	and	and	CCONJ
dpc-4685	31	19	persistent	persistent	ADJ
dpc-4685	31	20	.	.	PUNCT
dpc-4685	32	1	due	due	ADP
dpc-4685	32	2	to	to	ADP
dpc-4685	32	3	limited	limited	ADJ
dpc-4685	32	4	options	option	NOUN
dpc-4685	32	5	and	and	CCONJ
dpc-4685	32	6	the	the	DET
dpc-4685	32	7	unavailability	unavailability	NOUN
dpc-4685	32	8	of	of	ADP
dpc-4685	32	9	alitretinoin	alitretinoin	NOUN
dpc-4685	32	10	and	and	CCONJ
dpc-4685	32	11	dupilumab	dupilumab	NOUN
dpc-4685	32	12	in	in	ADP
dpc-4685	32	13	our	our	PRON
dpc-4685	32	14	hospital	hospital	NOUN
dpc-4685	32	15	,	,	PUNCT
dpc-4685	32	16	we	we	PRON
dpc-4685	32	17	offered	offer	VERB
dpc-4685	32	18	conventional	conventional	ADJ
dpc-4685	32	19	immunosuppressants	immunosuppressant	NOUN
dpc-4685	32	20	(	(	PUNCT
dpc-4685	32	21	eg	eg	NOUN
dpc-4685	32	22	methotrexate	methotrexate	NOUN
dpc-4685	32	23	,	,	PUNCT
dpc-4685	32	24	cyclosporin	cyclosporin	NOUN
dpc-4685	32	25	)	)	PUNCT
dpc-4685	32	26	,	,	PUNCT
dpc-4685	32	27	but	but	CCONJ
dpc-4685	32	28	the	the	DET
dpc-4685	32	29	2	2	NUM
dpc-4685	32	30	research	research	NOUN
dpc-4685	32	31	letter	letter	NOUN
dpc-4685	32	32	|	|	ADV
dpc-4685	32	33	dermatol	dermatol	ADJ
dpc-4685	32	34	pract	pract	NOUN
dpc-4685	32	35	concept	concept	NOUN
dpc-4685	32	36	.	.	PUNCT
dpc-4685	33	1	2025;15(1):4685	2025;15(1):4685	NUM
dpc-4685	33	2	patient	patient	NOUN
dpc-4685	33	3	opted	opt	VERB
dpc-4685	33	4	out	out	ADP
dpc-4685	33	5	.	.	PUNCT
dpc-4685	34	1	after	after	ADP
dpc-4685	34	2	explaining	explain	VERB
dpc-4685	34	3	possible	possible	ADJ
dpc-4685	34	4	side	side	NOUN
dpc-4685	34	5	effects	effect	NOUN
dpc-4685	34	6	,	,	PUNCT
dpc-4685	34	7	the	the	DET
dpc-4685	34	8	patient	patient	NOUN
dpc-4685	34	9	agreed	agree	VERB
dpc-4685	34	10	to	to	PART
dpc-4685	34	11	start	start	VERB
dpc-4685	34	12	on	on	ADP
dpc-4685	34	13	a	a	DET
dpc-4685	34	14	novel	novel	ADJ
dpc-4685	34	15	jak	jak	PROPN
dpc-4685	34	16	inhibitor	inhibitor	NOUN
dpc-4685	34	17	drug	drug	NOUN
dpc-4685	34	18	available	available	ADJ
dpc-4685	34	19	in	in	ADP
dpc-4685	34	20	our	our	PRON
dpc-4685	34	21	institution	institution	NOUN
dpc-4685	34	22	.	.	PUNCT
dpc-4685	35	1	upadacitinib	upadacitinib	NOUN
dpc-4685	35	2	15	15	NUM
dpc-4685	35	3	mg	mg	ADP
dpc-4685	35	4	once	once	ADV
dpc-4685	35	5	daily	daily	ADV
dpc-4685	35	6	was	be	AUX
dpc-4685	35	7	initiated	initiate	VERB
dpc-4685	35	8	,	,	PUNCT
dpc-4685	35	9	and	and	CCONJ
dpc-4685	35	10	a	a	DET
dpc-4685	35	11	follow	follow	VERB
dpc-4685	35	12	-	-	PUNCT
dpc-4685	35	13	up	up	ADP
dpc-4685	35	14	appointment	appointment	NOUN
dpc-4685	35	15	was	be	AUX
dpc-4685	35	16	arranged	arrange	VERB
dpc-4685	35	17	after	after	ADP
dpc-4685	35	18	2	2	NUM
dpc-4685	35	19	weeks	week	NOUN
dpc-4685	35	20	.	.	PUNCT
dpc-4685	36	1	the	the	DET
dpc-4685	36	2	patient	patient	NOUN
dpc-4685	36	3	exhibited	exhibit	VERB
dpc-4685	36	4	substantial	substantial	ADJ
dpc-4685	36	5	improvement	improvement	NOUN
dpc-4685	36	6	at	at	ADP
dpc-4685	36	7	follow	follow	NOUN
dpc-4685	36	8	-	-	PUNCT
dpc-4685	36	9	up	up	NOUN
dpc-4685	36	10	(	(	PUNCT
dpc-4685	36	11	figure	figure	NOUN
dpc-4685	36	12	2	2	NUM
dpc-4685	36	13	)	)	PUNCT
dpc-4685	36	14	.	.	PUNCT
dpc-4685	37	1	no	no	DET
dpc-4685	37	2	adverse	adverse	ADJ
dpc-4685	37	3	effects	effect	NOUN
dpc-4685	37	4	were	be	AUX
dpc-4685	37	5	documented	document	VERB
dpc-4685	37	6	.	.	PUNCT
dpc-4685	38	1	informed	informed	ADJ
dpc-4685	38	2	consent	consent	NOUN
dpc-4685	38	3	was	be	AUX
dpc-4685	38	4	obtained	obtain	VERB
dpc-4685	38	5	from	from	ADP
dpc-4685	38	6	the	the	DET
dpc-4685	38	7	patient	patient	NOUN
dpc-4685	38	8	to	to	PART
dpc-4685	38	9	share	share	VERB
dpc-4685	38	10	this	this	DET
dpc-4685	38	11	case	case	NOUN
dpc-4685	38	12	.	.	PUNCT
dpc-4685	39	1	conclusions	conclusion	NOUN
dpc-4685	39	2	hand	hand	VERB
dpc-4685	39	3	dermatitis	dermatitis	NOUN
dpc-4685	39	4	or	or	CCONJ
dpc-4685	39	5	hand	hand	NOUN
dpc-4685	39	6	eczema	eczema	NOUN
dpc-4685	39	7	is	be	AUX
dpc-4685	39	8	a	a	DET
dpc-4685	39	9	clinically	clinically	ADV
dpc-4685	39	10	diverse	diverse	ADJ
dpc-4685	39	11	illness	illness	NOUN
dpc-4685	39	12	in	in	ADP
dpc-4685	39	13	terms	term	NOUN
dpc-4685	39	14	of	of	ADP
dpc-4685	39	15	etiologies	etiology	NOUN
dpc-4685	39	16	and	and	CCONJ
dpc-4685	39	17	clinical	clinical	ADJ
dpc-4685	39	18	symptoms	symptom	NOUN
dpc-4685	39	19	.	.	PUNCT
dpc-4685	40	1	patients	patient	NOUN
dpc-4685	40	2	with	with	ADP
dpc-4685	40	3	refractory	refractory	NOUN
dpc-4685	40	4	chronic	chronic	ADJ
dpc-4685	40	5	hand	hand	NOUN
dpc-4685	40	6	eczema	eczema	NOUN
dpc-4685	40	7	who	who	PRON
dpc-4685	40	8	failed	fail	VERB
dpc-4685	40	9	multiple	multiple	ADJ
dpc-4685	40	10	management	management	NOUN
dpc-4685	40	11	options	option	NOUN
dpc-4685	40	12	,	,	PUNCT
dpc-4685	40	13	as	as	ADP
dpc-4685	40	14	in	in	ADP
dpc-4685	40	15	our	our	PRON
dpc-4685	40	16	patient	patient	NOUN
dpc-4685	40	17	,	,	PUNCT
dpc-4685	40	18	require	require	VERB
dpc-4685	40	19	other	other	ADJ
dpc-4685	40	20	options	option	NOUN
dpc-4685	40	21	such	such	ADJ
dpc-4685	40	22	as	as	ADP
dpc-4685	40	23	conventional	conventional	ADJ
dpc-4685	40	24	immunosuppressants	immunosuppressant	NOUN
dpc-4685	40	25	(	(	PUNCT
dpc-4685	40	26	eg	eg	NOUN
dpc-4685	40	27	cyclosporin	cyclosporin	NOUN
dpc-4685	40	28	,	,	PUNCT
dpc-4685	40	29	methotrexate	methotrexate	NOUN
dpc-4685	40	30	)	)	PUNCT
dpc-4685	40	31	or	or	CCONJ
dpc-4685	40	32	systemic	systemic	ADJ
dpc-4685	40	33	retinoids	retinoid	NOUN
dpc-4685	41	1	[	[	X
dpc-4685	41	2	1	1	NUM
dpc-4685	41	3	-	-	SYM
dpc-4685	41	4	3	3	NUM
dpc-4685	41	5	]	]	PUNCT
dpc-4685	41	6	.	.	PUNCT
dpc-4685	42	1	upadacitinib	upadacitinib	NOUN
dpc-4685	42	2	is	be	AUX
dpc-4685	42	3	an	an	DET
dpc-4685	42	4	oral	oral	ADJ
dpc-4685	42	5	medication	medication	NOUN
dpc-4685	42	6	figure	figure	NOUN
dpc-4685	42	7	1	1	NUM
dpc-4685	42	8	.	.	PUNCT
dpc-4685	42	9	thickening	thickening	NOUN
dpc-4685	42	10	of	of	ADP
dpc-4685	42	11	the	the	DET
dpc-4685	42	12	skin	skin	NOUN
dpc-4685	42	13	,	,	PUNCT
dpc-4685	42	14	scaling	scaling	NOUN
dpc-4685	42	15	,	,	PUNCT
dpc-4685	42	16	and	and	CCONJ
dpc-4685	42	17	areas	area	NOUN
dpc-4685	42	18	of	of	ADP
dpc-4685	42	19	hyperkeratosis	hyperkeratosis	NOUN
dpc-4685	42	20	on	on	ADP
dpc-4685	42	21	palmer	palmer	PROPN
dpc-4685	42	22	aspect	aspect	NOUN
dpc-4685	42	23	of	of	ADP
dpc-4685	42	24	both	both	DET
dpc-4685	42	25	hands	hand	NOUN
dpc-4685	42	26	,	,	PUNCT
dpc-4685	42	27	prior	prior	ADV
dpc-4685	42	28	to	to	ADP
dpc-4685	42	29	starting	start	VERB
dpc-4685	42	30	oral	oral	ADJ
dpc-4685	42	31	upadacitinib	upadacitinib	NOUN
dpc-4685	42	32	.	.	PUNCT
dpc-4685	43	1	figure	figure	NOUN
dpc-4685	43	2	2	2	NUM
dpc-4685	43	3	.	.	PUNCT
dpc-4685	44	1	after	after	ADP
dpc-4685	44	2	2	2	NUM
dpc-4685	44	3	weeks	week	NOUN
dpc-4685	44	4	of	of	ADP
dpc-4685	44	5	oral	oral	ADJ
dpc-4685	44	6	upadacitinib	upadacitinib	NOUN
dpc-4685	44	7	15	15	NUM
dpc-4685	44	8	mg	mg	ADP
dpc-4685	44	9	once	once	ADV
dpc-4685	44	10	daily	daily	ADV
dpc-4685	44	11	.	.	PUNCT
dpc-4685	45	1	research	research	NOUN
dpc-4685	45	2	letter	letter	NOUN
dpc-4685	46	1	|	|	ADV
dpc-4685	46	2	dermatol	dermatol	ADJ
dpc-4685	46	3	pract	pract	NOUN
dpc-4685	46	4	concept	concept	NOUN
dpc-4685	46	5	.	.	PUNCT
dpc-4685	47	1	2025;15(1):4685	2025;15(1):4685	NUM
dpc-4685	47	2	3	3	NUM
dpc-4685	47	3	doi:10.4103/0019	doi:10.4103/0019	X
dpc-4685	47	4	-	-	PUNCT
dpc-4685	47	5	5154.131372	5154.131372	NUM
dpc-4685	47	6	.	.	PUNCT
dpc-4685	48	1	pmid	pmid	NOUN
dpc-4685	48	2	:	:	PUNCT
dpc-4685	48	3	24891648	24891648	NUM
dpc-4685	48	4	.	.	PUNCT
dpc-4685	49	1	pmcid	pmcid	NOUN
dpc-4685	49	2	:	:	PUNCT
dpc-4685	49	3	pmc4037938	pmc4037938	ADJ
dpc-4685	49	4	.	.	PUNCT
dpc-4685	50	1	2	2	X
dpc-4685	50	2	.	.	X
dpc-4685	50	3	thyssen	thyssen	PROPN
dpc-4685	50	4	jp	jp	PROPN
dpc-4685	50	5	,	,	PUNCT
dpc-4685	50	6	schuttelaar	schuttelaar	PROPN
dpc-4685	50	7	mla	mla	PROPN
dpc-4685	50	8	,	,	PUNCT
dpc-4685	50	9	alfonso	alfonso	PROPN
dpc-4685	50	10	jh	jh	PROPN
dpc-4685	50	11	,	,	PUNCT
dpc-4685	50	12	et	et	PROPN
dpc-4685	50	13	al	al	PROPN
dpc-4685	50	14	.	.	PUNCT
dpc-4685	50	15	guidelines	guideline	NOUN
dpc-4685	50	16	for	for	ADP
dpc-4685	50	17	diagnosis	diagnosis	NOUN
dpc-4685	50	18	,	,	PUNCT
dpc-4685	50	19	prevention	prevention	NOUN
dpc-4685	50	20	,	,	PUNCT
dpc-4685	50	21	and	and	CCONJ
dpc-4685	50	22	treatment	treatment	NOUN
dpc-4685	50	23	of	of	ADP
dpc-4685	50	24	hand	hand	NOUN
dpc-4685	50	25	eczema	eczema	NOUN
dpc-4685	50	26	.	.	PUNCT
dpc-4685	50	27	 	 	SPACE
dpc-4685	50	28	contact	contact	NOUN
dpc-4685	50	29	dermatitis	dermatitis	NOUN
dpc-4685	50	30	.	.	PUNCT
dpc-4685	51	1	2022;86(5):357	2022;86(5):357	PROPN
dpc-4685	51	2	-	-	PUNCT
dpc-4685	51	3	378	378	NUM
dpc-4685	51	4	.	.	PUNCT
dpc-4685	52	1	doi:10.1111	doi:10.1111	ADJ
dpc-4685	52	2	/	/	SYM
dpc-4685	52	3	cod.14035	cod.14035	NOUN
dpc-4685	52	4	.	.	PUNCT
dpc-4685	53	1	pmid	pmid	NOUN
dpc-4685	53	2	:	:	PUNCT
dpc-4685	53	3	34971008	34971008	NUM
dpc-4685	53	4	.	.	PUNCT
dpc-4685	54	1	3	3	X
dpc-4685	54	2	.	.	X
dpc-4685	54	3	elsner	elsner	NOUN
dpc-4685	54	4	p	p	NOUN
dpc-4685	54	5	,	,	PUNCT
dpc-4685	54	6	agner	agner	NOUN
dpc-4685	54	7	t.	t.	PROPN
dpc-4685	54	8	hand	hand	PROPN
dpc-4685	54	9	eczema	eczema	NOUN
dpc-4685	54	10	:	:	PUNCT
dpc-4685	54	11	treatment	treatment	NOUN
dpc-4685	54	12	.	.	PUNCT
dpc-4685	54	13	 	 	SPACE
dpc-4685	55	1	j	j	PROPN
dpc-4685	55	2	eur	eur	PROPN
dpc-4685	55	3	acad	acad	PROPN
dpc-4685	55	4	dermatol	dermatol	NOUN
dpc-4685	55	5	venereol	venereol	NOUN
dpc-4685	55	6	.	.	PUNCT
dpc-4685	56	1	2020;34	2020;34	NUM
dpc-4685	56	2	suppl	suppl	ADJ
dpc-4685	56	3	1:13	1:13	NUM
dpc-4685	56	4	-	-	SYM
dpc-4685	56	5	21	21	NUM
dpc-4685	56	6	.	.	PUNCT
dpc-4685	57	1	doi:10.1111	doi:10.1111	NOUN
dpc-4685	57	2	/	/	SYM
dpc-4685	57	3	jdv.16062	jdv.16062	ADP
dpc-4685	57	4	.	.	PUNCT
dpc-4685	58	1	pmid	pmid	NOUN
dpc-4685	58	2	:	:	PUNCT
dpc-4685	58	3	31860736	31860736	NUM
dpc-4685	58	4	.	.	PUNCT
dpc-4685	59	1	4	4	X
dpc-4685	59	2	.	.	X
dpc-4685	59	3	guttman	guttman	ADJ
dpc-4685	59	4	-	-	PUNCT
dpc-4685	59	5	yassky	yassky	NOUN
dpc-4685	59	6	e	e	NOUN
dpc-4685	59	7	,	,	PUNCT
dpc-4685	59	8	teixeira	teixeira	PROPN
dpc-4685	59	9	hd	hd	PROPN
dpc-4685	59	10	,	,	PUNCT
dpc-4685	59	11	simpson	simpson	PROPN
dpc-4685	59	12	el	el	PROPN
dpc-4685	59	13	,	,	PUNCT
dpc-4685	59	14	et	et	PROPN
dpc-4685	59	15	al	al	PROPN
dpc-4685	59	16	.	.	PROPN
dpc-4685	60	1	once	once	ADV
dpc-4685	60	2	-	-	PUNCT
dpc-4685	60	3	daily	daily	ADJ
dpc-4685	60	4	upadacitinib	upadacitinib	NOUN
dpc-4685	60	5	versus	versus	ADP
dpc-4685	60	6	placebo	placebo	NOUN
dpc-4685	60	7	in	in	ADP
dpc-4685	60	8	adolescents	adolescent	NOUN
dpc-4685	60	9	and	and	CCONJ
dpc-4685	60	10	adults	adult	NOUN
dpc-4685	60	11	with	with	ADP
dpc-4685	60	12	moderate	moderate	ADJ
dpc-4685	60	13	-	-	PUNCT
dpc-4685	60	14	to	to	ADP
dpc-4685	60	15	-	-	PUNCT
dpc-4685	60	16	severe	severe	ADJ
dpc-4685	60	17	atopic	atopic	NOUN
dpc-4685	60	18	dermatitis	dermatitis	NOUN
dpc-4685	60	19	(	(	PUNCT
dpc-4685	60	20	measure	measure	VERB
dpc-4685	60	21	up	up	ADV
dpc-4685	60	22	1	1	NUM
dpc-4685	60	23	and	and	CCONJ
dpc-4685	60	24	measure	measure	VERB
dpc-4685	60	25	up	up	ADV
dpc-4685	60	26	2	2	NUM
dpc-4685	60	27	):	):	PUNCT
dpc-4685	60	28	results	result	NOUN
dpc-4685	60	29	from	from	ADP
dpc-4685	60	30	two	two	NUM
dpc-4685	60	31	replicate	replicate	ADJ
dpc-4685	60	32	double	double	ADJ
dpc-4685	60	33	-	-	PUNCT
dpc-4685	60	34	blind	blind	ADJ
dpc-4685	60	35	,	,	PUNCT
dpc-4685	60	36	randomised	randomise	VERB
dpc-4685	60	37	controlled	control	VERB
dpc-4685	60	38	phase	phase	NOUN
dpc-4685	60	39	3	3	NUM
dpc-4685	60	40	trials	trial	NOUN
dpc-4685	60	41	.	.	PUNCT
dpc-4685	61	1	lancet	lancet	NOUN
dpc-4685	61	2	.	.	PUNCT
dpc-4685	62	1	2021	2021	NUM
dpc-4685	63	1	5;397(10290):2151	5;397(10290):2151	NUM
dpc-4685	63	2	-	-	SYM
dpc-4685	63	3	2168	2168	NUM
dpc-4685	63	4	.	.	PUNCT
dpc-4685	64	1	doi	doi	NOUN
dpc-4685	64	2	:	:	PUNCT
dpc-4685	64	3	10.1016	10.1016	NUM
dpc-4685	64	4	/	/	SYM
dpc-4685	64	5	s0140	s0140	PROPN
dpc-4685	64	6	-	-	PUNCT
dpc-4685	64	7	6736(21)00588	6736(21)00588	NOUN
dpc-4685	64	8	-	-	PUNCT
dpc-4685	64	9	2	2	NUM
dpc-4685	64	10	.	.	PUNCT
dpc-4685	65	1	epub	epub	NOUN
dpc-4685	65	2	2021	2021	NUM
dpc-4685	65	3	21	21	NUM
dpc-4685	65	4	.	.	PUNCT
dpc-4685	66	1	erratum	erratum	PROPN
dpc-4685	66	2	in	in	ADP
dpc-4685	66	3	:	:	PUNCT
dpc-4685	66	4	lancet	lancet	NOUN
dpc-4685	66	5	.	.	PUNCT
dpc-4685	67	1	2021	2021	NUM
dpc-4685	67	2	jun	jun	PROPN
dpc-4685	67	3	5;397(10290):2150	5;397(10290):2150	NUM
dpc-4685	67	4	.	.	PUNCT
dpc-4685	68	1	doi	doi	NOUN
dpc-4685	68	2	:	:	PUNCT
dpc-4685	68	3	10.1016	10.1016	NUM
dpc-4685	68	4	/	/	SYM
dpc-4685	68	5	s01406736(21)01214	s01406736(21)01214	ADJ
dpc-4685	68	6	-	-	PUNCT
dpc-4685	68	7	9	9	NUM
dpc-4685	68	8	.	.	PUNCT
dpc-4685	69	1	pmid	pmid	NOUN
dpc-4685	69	2	:	:	PUNCT
dpc-4685	69	3	34023008	34023008	NUM
dpc-4685	69	4	.	.	PUNCT
dpc-4685	70	1	that	that	PRON
dpc-4685	70	2	has	have	AUX
dpc-4685	70	3	received	receive	VERB
dpc-4685	70	4	approval	approval	NOUN
dpc-4685	70	5	from	from	ADP
dpc-4685	70	6	the	the	DET
dpc-4685	70	7	fda	fda	PROPN
dpc-4685	70	8	for	for	ADP
dpc-4685	70	9	the	the	DET
dpc-4685	70	10	management	management	NOUN
dpc-4685	70	11	of	of	ADP
dpc-4685	70	12	moderatetosevere	moderatetosevere	PROPN
dpc-4685	70	13	atopic	atopic	PROPN
dpc-4685	70	14	dermatitis	dermatitis	NOUN
dpc-4685	70	15	in	in	ADP
dpc-4685	70	16	adults	adult	NOUN
dpc-4685	70	17	and	and	CCONJ
dpc-4685	70	18	adolescents	adolescent	NOUN
dpc-4685	70	19	aged	age	VERB
dpc-4685	70	20	12	12	NUM
dpc-4685	70	21	years	year	NOUN
dpc-4685	70	22	and	and	CCONJ
dpc-4685	70	23	older	old	ADJ
dpc-4685	70	24	.	.	PUNCT
dpc-4685	71	1	the	the	DET
dpc-4685	71	2	mechanism	mechanism	NOUN
dpc-4685	71	3	of	of	ADP
dpc-4685	71	4	action	action	NOUN
dpc-4685	71	5	of	of	ADP
dpc-4685	71	6	upadacitinib	upadacitinib	NOUN
dpc-4685	71	7	involves	involve	VERB
dpc-4685	71	8	the	the	DET
dpc-4685	71	9	inhibition	inhibition	NOUN
dpc-4685	71	10	of	of	ADP
dpc-4685	71	11	jak	jak	PROPN
dpc-4685	72	1	[	[	X
dpc-4685	72	2	4	4	NUM
dpc-4685	72	3	]	]	PUNCT
dpc-4685	72	4	.	.	PUNCT
dpc-4685	73	1	this	this	DET
dpc-4685	73	2	case	case	NOUN
dpc-4685	73	3	highlights	highlight	VERB
dpc-4685	73	4	the	the	DET
dpc-4685	73	5	efficacy	efficacy	NOUN
dpc-4685	73	6	of	of	ADP
dpc-4685	73	7	upadacitinib	upadacitinib	NOUN
dpc-4685	73	8	as	as	ADP
dpc-4685	73	9	a	a	DET
dpc-4685	73	10	promising	promising	ADJ
dpc-4685	73	11	therapeutic	therapeutic	ADJ
dpc-4685	73	12	option	option	NOUN
dpc-4685	73	13	for	for	ADP
dpc-4685	73	14	refractory	refractory	NOUN
dpc-4685	73	15	hand	hand	NOUN
dpc-4685	73	16	eczema	eczema	NOUN
dpc-4685	73	17	.	.	PUNCT
dpc-4685	74	1	despite	despite	SCONJ
dpc-4685	74	2	multiple	multiple	ADJ
dpc-4685	74	3	treatment	treatment	NOUN
dpc-4685	74	4	trials	trial	NOUN
dpc-4685	74	5	,	,	PUNCT
dpc-4685	74	6	the	the	DET
dpc-4685	74	7	patient	patient	NOUN
dpc-4685	74	8	did	do	AUX
dpc-4685	74	9	not	not	PART
dpc-4685	74	10	achieve	achieve	VERB
dpc-4685	74	11	remission	remission	NOUN
dpc-4685	74	12	.	.	PUNCT
dpc-4685	75	1	however	however	ADV
dpc-4685	75	2	,	,	PUNCT
dpc-4685	75	3	the	the	DET
dpc-4685	75	4	initiation	initiation	NOUN
dpc-4685	75	5	of	of	ADP
dpc-4685	75	6	oral	oral	ADJ
dpc-4685	75	7	upadacitinib	upadacitinib	NOUN
dpc-4685	75	8	resulted	result	VERB
dpc-4685	75	9	in	in	ADP
dpc-4685	75	10	remarkable	remarkable	ADJ
dpc-4685	75	11	improvement	improvement	NOUN
dpc-4685	75	12	.	.	PUNCT
dpc-4685	76	1	further	further	ADJ
dpc-4685	76	2	studies	study	NOUN
dpc-4685	76	3	are	be	AUX
dpc-4685	76	4	needed	need	VERB
dpc-4685	76	5	to	to	PART
dpc-4685	76	6	determine	determine	VERB
dpc-4685	76	7	the	the	DET
dpc-4685	76	8	long	long	ADJ
dpc-4685	76	9	-	-	PUNCT
dpc-4685	76	10	term	term	NOUN
dpc-4685	76	11	efficacy	efficacy	NOUN
dpc-4685	76	12	and	and	CCONJ
dpc-4685	76	13	safety	safety	NOUN
dpc-4685	76	14	of	of	ADP
dpc-4685	76	15	upadacitinib	upadacitinib	NOUN
dpc-4685	76	16	in	in	ADP
dpc-4685	76	17	treating	treat	VERB
dpc-4685	76	18	hand	hand	NOUN
dpc-4685	76	19	eczema	eczema	NOUN
dpc-4685	76	20	.	.	PUNCT
dpc-4685	77	1	references	reference	NOUN
dpc-4685	77	2	1	1	NUM
dpc-4685	77	3	.	.	PUNCT
dpc-4685	78	1	agarwal	agarwal	PROPN
dpc-4685	78	2	us	we	PRON
dpc-4685	78	3	,	,	PUNCT
dpc-4685	78	4	besarwal	besarwal	VERB
dpc-4685	78	5	rk	rk	PRON
dpc-4685	78	6	,	,	PUNCT
dpc-4685	78	7	gupta	gupta	PROPN
dpc-4685	78	8	r	r	NOUN
dpc-4685	78	9	,	,	PUNCT
dpc-4685	78	10	agarwal	agarwal	PROPN
dpc-4685	78	11	p	p	PROPN
dpc-4685	78	12	,	,	PUNCT
dpc-4685	78	13	napalia	napalia	PROPN
dpc-4685	78	14	s.	s.	PROPN
dpc-4685	78	15	hand	hand	PROPN
dpc-4685	78	16	eczema	eczema	PROPN
dpc-4685	78	17	.	.	PUNCT
dpc-4685	79	1	indian	indian	PROPN
dpc-4685	79	2	j	j	PROPN
dpc-4685	79	3	dermatol	dermatol	NOUN
dpc-4685	79	4	.	.	PUNCT
dpc-4685	80	1	2014;59(3):213	2014;59(3):213	NUM
dpc-4685	80	2	-	-	SYM
dpc-4685	80	3	224	224	NUM
dpc-4685	80	4	.	.	PUNCT