id	sid	tid	token	lemma	pos
dpc-4976	1	1	dermatology	dermatology	NOUN
dpc-4976	1	2	:	:	PUNCT
dpc-4976	1	3	practical	practical	ADJ
dpc-4976	1	4	and	and	CCONJ
dpc-4976	1	5	conceptual	conceptual	ADJ
dpc-4976	1	6	original	original	ADJ
dpc-4976	1	7	article	article	NOUN
dpc-4976	1	8	|	|	ADV
dpc-4976	1	9	dermatol	dermatol	ADJ
dpc-4976	1	10	pract	pract	NOUN
dpc-4976	1	11	concept	concept	NOUN
dpc-4976	1	12	.	.	PUNCT
dpc-4976	2	1	2025;15(1):4976	2025;15(1):4976	NUM
dpc-4976	2	2	1	1	NUM
dpc-4976	2	3	evaluating	evaluate	VERB
dpc-4976	2	4	the	the	DET
dpc-4976	2	5	efficacy	efficacy	NOUN
dpc-4976	2	6	of	of	ADP
dpc-4976	2	7	bimekizumab	bimekizumab	NOUN
dpc-4976	2	8	across	across	ADP
dpc-4976	2	9	the	the	DET
dpc-4976	2	10	different	different	ADJ
dpc-4976	2	11	sensitive	sensitive	ADJ
dpc-4976	2	12	areas	area	NOUN
dpc-4976	2	13	in	in	ADP
dpc-4976	2	14	moderate	moderate	ADJ
dpc-4976	2	15	-	-	PUNCT
dpc-4976	2	16	to	to	ADP
dpc-4976	2	17	-	-	PUNCT
dpc-4976	2	18	severe	severe	ADJ
dpc-4976	2	19	psoriasis	psoriasis	NOUN
dpc-4976	2	20	:	:	PUNCT
dpc-4976	2	21	a	a	DET
dpc-4976	2	22	52	52	NUM
dpc-4976	2	23	-	-	PUNCT
dpc-4976	2	24	week	week	NOUN
dpc-4976	2	25	italian	italian	ADJ
dpc-4976	2	26	multicenter	multicenter	NOUN
dpc-4976	2	27	real	real	ADJ
dpc-4976	2	28	-	-	PUNCT
dpc-4976	2	29	life	life	NOUN
dpc-4976	2	30	lazio	lazio	NOUN
dpc-4976	2	31	experience	experience	NOUN
dpc-4976	2	32	annunziata	annunziata	VERB
dpc-4976	2	33	dattola1	dattola1	PROPN
dpc-4976	2	34	,	,	PUNCT
dpc-4976	2	35	nicoletta	nicoletta	PROPN
dpc-4976	2	36	bernardini2	bernardini2	PROPN
dpc-4976	2	37	,	,	PUNCT
dpc-4976	2	38	elena	elena	PROPN
dpc-4976	2	39	campione3	campione3	PROPN
dpc-4976	2	40	,	,	PUNCT
dpc-4976	2	41	emanuele	emanuele	PROPN
dpc-4976	2	42	amore1	amore1	PROPN
dpc-4976	2	43	,	,	PUNCT
dpc-4976	2	44	simone	simone	PROPN
dpc-4976	2	45	 	 	SPACE
dpc-4976	2	46	amato1	amato1	PROPN
dpc-4976	2	47	,	,	PUNCT
dpc-4976	2	48	giacomo	giacomo	NOUN
dpc-4976	2	49	caldarola4	caldarola4	PROPN
dpc-4976	2	50	,	,	PUNCT
dpc-4976	2	51	clara	clara	PROPN
dpc-4976	2	52	de	de	PROPN
dpc-4976	2	53	simone4	simone4	PROPN
dpc-4976	2	54	,	,	PUNCT
dpc-4976	2	55	domenico	domenico	PROPN
dpc-4976	2	56	giordano5	giordano5	PROPN
dpc-4976	2	57	,	,	PUNCT
dpc-4976	2	58	gaia	gaia	PROPN
dpc-4976	2	59	 	 	SPACE
dpc-4976	2	60	moretta6	moretta6	PROPN
dpc-4976	2	61	,	,	PUNCT
dpc-4976	2	62	vincenzo	vincenzo	PROPN
dpc-4976	2	63	panasiti7	panasiti7	PROPN
dpc-4976	2	64	,	,	PUNCT
dpc-4976	2	65	gianluca	gianluca	PROPN
dpc-4976	2	66	pagnanelli6	pagnanelli6	PROPN
dpc-4976	2	67	,	,	PUNCT
dpc-4976	2	68	vincenzo	vincenzo	PROPN
dpc-4976	2	69	roberti7	roberti7	PROPN
dpc-4976	2	70	,	,	PUNCT
dpc-4976	2	71	ruslana	ruslana	PROPN
dpc-4976	2	72	 	 	SPACE
dpc-4976	2	73	gaeta	gaeta	PROPN
dpc-4976	2	74	 	 	SPACE
dpc-4976	2	75	shumak3	shumak3	PROPN
dpc-4976	2	76	,	,	PUNCT
dpc-4976	2	77	nevena	nevena	PROPN
dpc-4976	2	78	skorza2	skorza2	PROPN
dpc-4976	2	79	,	,	PUNCT
dpc-4976	2	80	ersilia	ersilia	PROPN
dpc-4976	2	81	tolino2	tolino2	PROPN
dpc-4976	2	82	,	,	PUNCT
dpc-4976	2	83	paola	paola	PROPN
dpc-4976	2	84	tribuzi8	tribuzi8	PROPN
dpc-4976	2	85	,	,	PUNCT
dpc-4976	2	86	salvatore	salvatore	PROPN
dpc-4976	2	87	zanframundo7	zanframundo7	PROPN
dpc-4976	2	88	,	,	PUNCT
dpc-4976	2	89	luca	luca	PROPN
dpc-4976	2	90	 	 	SPACE
dpc-4976	2	91	bianchi3	bianchi3	PROPN
dpc-4976	2	92	,	,	PUNCT
dpc-4976	2	93	severino	severino	PROPN
dpc-4976	2	94	persechino5	persechino5	PROPN
dpc-4976	2	95	,	,	PUNCT
dpc-4976	2	96	concetta	concetta	PROPN
dpc-4976	2	97	potenza2	potenza2	PROPN
dpc-4976	2	98	,	,	PUNCT
dpc-4976	2	99	giovanni	giovanni	PROPN
dpc-4976	2	100	pellacani1	pellacani1	NOUN
dpc-4976	2	101	,	,	PUNCT
dpc-4976	2	102	ketty	ketty	PROPN
dpc-4976	2	103	peris4	peris4	PROPN
dpc-4976	2	104	,	,	PUNCT
dpc-4976	2	105	antonio	antonio	PROPN
dpc-4976	2	106	giovanni	giovanni	PROPN
dpc-4976	2	107	richetta1	richetta1	PROPN
dpc-4976	2	108	1	1	NUM
dpc-4976	2	109	dermatology	dermatology	NOUN
dpc-4976	2	110	unit	unit	NOUN
dpc-4976	2	111	,	,	PUNCT
dpc-4976	2	112	department	department	NOUN
dpc-4976	2	113	of	of	ADP
dpc-4976	2	114	clinical	clinical	ADJ
dpc-4976	2	115	internal	internal	ADJ
dpc-4976	2	116	,	,	PUNCT
dpc-4976	2	117	anesthesiological	anesthesiological	ADJ
dpc-4976	2	118	and	and	CCONJ
dpc-4976	2	119	cardiovascular	cardiovascular	ADJ
dpc-4976	2	120	science	science	NOUN
dpc-4976	2	121	,	,	PUNCT
dpc-4976	2	122	university	university	NOUN
dpc-4976	2	123	of	of	ADP
dpc-4976	2	124	la	la	PROPN
dpc-4976	2	125	sapienza	sapienza	PROPN
dpc-4976	2	126	,	,	PUNCT
dpc-4976	2	127	rome	rome	PROPN
dpc-4976	2	128	,	,	PUNCT
dpc-4976	2	129	italy	italy	PROPN
dpc-4976	2	130	2	2	NUM
dpc-4976	2	131	dermatology	dermatology	NOUN
dpc-4976	2	132	unit	unit	NOUN
dpc-4976	2	133	“	"	PUNCT
dpc-4976	2	134	daniele	daniele	PROPN
dpc-4976	2	135	innocenzi	innocenzi	PROPN
dpc-4976	2	136	”	"	PUNCT
dpc-4976	2	137	,	,	PUNCT
dpc-4976	2	138	asl	asl	PROPN
dpc-4976	2	139	latina	latina	PROPN
dpc-4976	2	140	,	,	PUNCT
dpc-4976	2	141	department	department	NOUN
dpc-4976	2	142	of	of	ADP
dpc-4976	2	143	medico	medico	PROPN
dpc-4976	2	144	-	-	PUNCT
dpc-4976	2	145	surgical	surgical	ADJ
dpc-4976	2	146	sciences	science	NOUN
dpc-4976	2	147	and	and	CCONJ
dpc-4976	2	148	biotechnologies	biotechnology	NOUN
dpc-4976	2	149	,	,	PUNCT
dpc-4976	2	150	sapienza	sapienza	PROPN
dpc-4976	2	151	university	university	PROPN
dpc-4976	2	152	of	of	ADP
dpc-4976	2	153	 	 	SPACE
dpc-4976	2	154	rome	rome	PROPN
dpc-4976	2	155	,	,	PUNCT
dpc-4976	2	156	polo	polo	NOUN
dpc-4976	2	157	pontino	pontino	NOUN
dpc-4976	2	158	,	,	PUNCT
dpc-4976	2	159	italy	italy	PROPN
dpc-4976	2	160	3	3	NUM
dpc-4976	2	161	dermatology	dermatology	NOUN
dpc-4976	2	162	unit	unit	NOUN
dpc-4976	2	163	,	,	PUNCT
dpc-4976	2	164	department	department	NOUN
dpc-4976	2	165	of	of	ADP
dpc-4976	2	166	“	"	PUNCT
dpc-4976	2	167	medicina	medicina	PROPN
dpc-4976	2	168	dei	dei	PROPN
dpc-4976	2	169	sistemi	sistemi	PROPN
dpc-4976	2	170	”	"	PUNCT
dpc-4976	2	171	,	,	PUNCT
dpc-4976	2	172	university	university	NOUN
dpc-4976	2	173	of	of	ADP
dpc-4976	2	174	rome	rome	PROPN
dpc-4976	2	175	tor	tor	PROPN
dpc-4976	2	176	vergata	vergata	PROPN
dpc-4976	2	177	,	,	PUNCT
dpc-4976	2	178	rome	rome	PROPN
dpc-4976	2	179	,	,	PUNCT
dpc-4976	2	180	italy	italy	PROPN
dpc-4976	2	181	4	4	NUM
dpc-4976	2	182	uoc	uoc	PROPN
dpc-4976	2	183	di	di	NOUN
dpc-4976	2	184	dermatologia	dermatologia	PROPN
dpc-4976	2	185	,	,	PUNCT
dpc-4976	2	186	dipartimento	dipartimento	ADP
dpc-4976	2	187	di	di	PROPN
dpc-4976	2	188	scienze	scienze	PROPN
dpc-4976	2	189	mediche	mediche	PROPN
dpc-4976	2	190	e	e	PROPN
dpc-4976	2	191	chirurgiche	chirurgiche	PROPN
dpc-4976	2	192	,	,	PUNCT
dpc-4976	2	193	fondazione	fondazione	PROPN
dpc-4976	2	194	policlinico	policlinico	PROPN
dpc-4976	2	195	universitario	universitario	PROPN
dpc-4976	2	196	a.	a.	PROPN
dpc-4976	2	197	gemelli	gemelli	PROPN
dpc-4976	2	198	irccs	irccs	PROPN
dpc-4976	2	199	,	,	PUNCT
dpc-4976	2	200	rome	rome	PROPN
dpc-4976	2	201	,	,	PUNCT
dpc-4976	2	202	italy	italy	PROPN
dpc-4976	2	203	,	,	PUNCT
dpc-4976	2	204	dermatologia	dermatologia	PROPN
dpc-4976	2	205	,	,	PUNCT
dpc-4976	2	206	dipartimento	dipartimento	ADP
dpc-4976	2	207	di	di	NOUN
dpc-4976	2	208	medicina	medicina	PROPN
dpc-4976	2	209	e	e	PROPN
dpc-4976	2	210	chirurgia	chirurgia	PROPN
dpc-4976	2	211	traslazionale	traslazionale	PROPN
dpc-4976	2	212	,	,	PUNCT
dpc-4976	2	213	università	università	PROPN
dpc-4976	2	214	cattolica	cattolica	PROPN
dpc-4976	2	215	del	del	PROPN
dpc-4976	2	216	sacro	sacro	PROPN
dpc-4976	2	217	cuore	cuore	PROPN
dpc-4976	2	218	,	,	PUNCT
dpc-4976	2	219	rome	rome	PROPN
dpc-4976	2	220	,	,	PUNCT
dpc-4976	2	221	italy	italy	PROPN
dpc-4976	2	222	  	  	SPACE
dpc-4976	2	223	5	5	NUM
dpc-4976	2	224	department	department	NOUN
dpc-4976	2	225	of	of	ADP
dpc-4976	2	226	neurosciences	neuroscience	NOUN
dpc-4976	2	227	,	,	PUNCT
dpc-4976	2	228	mental	mental	ADJ
dpc-4976	2	229	health	health	NOUN
dpc-4976	2	230	and	and	CCONJ
dpc-4976	2	231	sensory	sensory	ADJ
dpc-4976	2	232	organs	organ	NOUN
dpc-4976	2	233	,	,	PUNCT
dpc-4976	2	234	sapienza	sapienza	PROPN
dpc-4976	2	235	university	university	PROPN
dpc-4976	2	236	,	,	PUNCT
dpc-4976	2	237	rome	rome	PROPN
dpc-4976	2	238	,	,	PUNCT
dpc-4976	2	239	italy	italy	PROPN
dpc-4976	2	240	6	6	NUM
dpc-4976	2	241	department	department	NOUN
dpc-4976	2	242	of	of	ADP
dpc-4976	2	243	dermatology	dermatology	NOUN
dpc-4976	2	244	,	,	PUNCT
dpc-4976	2	245	istituto	istituto	X
dpc-4976	2	246	dermopatico	dermopatico	NOUN
dpc-4976	2	247	dell’immacolata	dell’immacolata	NOUN
dpc-4976	2	248	irccs	ircc	VERB
dpc-4976	2	249	roma	roma	PROPN
dpc-4976	2	250	7	7	NUM
dpc-4976	2	251	department	department	NOUN
dpc-4976	2	252	of	of	ADP
dpc-4976	2	253	medicine	medicine	NOUN
dpc-4976	2	254	and	and	CCONJ
dpc-4976	2	255	surgery	surgery	NOUN
dpc-4976	2	256	,	,	PUNCT
dpc-4976	2	257	università	università	PROPN
dpc-4976	2	258	campus	campus	PROPN
dpc-4976	2	259	bio	bio	PROPN
dpc-4976	2	260	-	-	ADJ
dpc-4976	2	261	medico	medico	ADJ
dpc-4976	2	262	di	di	X
dpc-4976	2	263	roma	roma	PROPN
dpc-4976	2	264	,	,	PUNCT
dpc-4976	2	265	roma	roma	PROPN
dpc-4976	2	266	,	,	PUNCT
dpc-4976	2	267	italy	italy	PROPN
dpc-4976	2	268	;	;	PUNCT
dpc-4976	2	269	operative	operative	ADJ
dpc-4976	2	270	research	research	NOUN
dpc-4976	2	271	unit	unit	NOUN
dpc-4976	2	272	of	of	ADP
dpc-4976	2	273	dermatology	dermatology	NOUN
dpc-4976	2	274	,	,	PUNCT
dpc-4976	2	275	fondazione	fondazione	NOUN
dpc-4976	2	276	policlinico	policlinico	PROPN
dpc-4976	2	277	universitario	universitario	PROPN
dpc-4976	2	278	campus	campus	PROPN
dpc-4976	2	279	bio	bio	PROPN
dpc-4976	2	280	-	-	NOUN
dpc-4976	2	281	medico	medico	NOUN
dpc-4976	2	282	,	,	PUNCT
dpc-4976	2	283	via	via	ADP
dpc-4976	2	284	alvaro	alvaro	PROPN
dpc-4976	2	285	del	del	PROPN
dpc-4976	2	286	portillo	portillo	PROPN
dpc-4976	2	287	,	,	PUNCT
dpc-4976	2	288	roma	roma	PROPN
dpc-4976	2	289	,	,	PUNCT
dpc-4976	2	290	italy	italy	PROPN
dpc-4976	2	291	8	8	NUM
dpc-4976	2	292	uosd	uosd	ADJ
dpc-4976	2	293	ospedale	ospedale	PROPN
dpc-4976	2	294	belcolle	belcolle	PROPN
dpc-4976	2	295	asl	asl	PROPN
dpc-4976	2	296	viterbo	viterbo	PROPN
dpc-4976	2	297	key	key	PROPN
dpc-4976	2	298	words	word	NOUN
dpc-4976	2	299	:	:	PUNCT
dpc-4976	2	300	bimekizumab	bimekizumab	ADV
dpc-4976	2	301	,	,	PUNCT
dpc-4976	2	302	il-17	il-17	ADV
dpc-4976	2	303	inhibitor	inhibitor	NOUN
dpc-4976	2	304	,	,	PUNCT
dpc-4976	2	305	biologics	biologic	NOUN
dpc-4976	2	306	,	,	PUNCT
dpc-4976	2	307	il-17	il-17	X
dpc-4976	2	308	,	,	PUNCT
dpc-4976	2	309	difficult	difficult	ADJ
dpc-4976	2	310	-	-	PUNCT
dpc-4976	2	311	to	to	ADP
dpc-4976	2	312	-	-	PUNCT
dpc-4976	2	313	treat	treat	NOUN
dpc-4976	2	314	areas	area	NOUN
dpc-4976	2	315	,	,	PUNCT
dpc-4976	2	316	psoriasis	psoriasis	NOUN
dpc-4976	2	317	citation	citation	NOUN
dpc-4976	2	318	:	:	PUNCT
dpc-4976	2	319	dattola	dattola	PROPN
dpc-4976	2	320	a	a	PRON
dpc-4976	2	321	,	,	PUNCT
dpc-4976	2	322	bernardini	bernardini	PROPN
dpc-4976	2	323	n	n	NOUN
dpc-4976	2	324	,	,	PUNCT
dpc-4976	2	325	campione	campione	PROPN
dpc-4976	2	326	e	e	NOUN
dpc-4976	2	327	,	,	PUNCT
dpc-4976	2	328	et	et	PROPN
dpc-4976	2	329	al	al	PROPN
dpc-4976	2	330	.	.	PUNCT
dpc-4976	2	331	evaluating	evaluate	VERB
dpc-4976	2	332	the	the	DET
dpc-4976	2	333	efficacy	efficacy	NOUN
dpc-4976	2	334	of	of	ADP
dpc-4976	2	335	bimekizumab	bimekizumab	NOUN
dpc-4976	2	336	across	across	ADP
dpc-4976	2	337	the	the	DET
dpc-4976	2	338	different	different	ADJ
dpc-4976	2	339	sensitive	sensitive	ADJ
dpc-4976	2	340	areas	area	NOUN
dpc-4976	2	341	in	in	ADP
dpc-4976	2	342	moderate	moderate	ADJ
dpc-4976	2	343	-	-	PUNCT
dpc-4976	2	344	to	to	ADP
dpc-4976	2	345	-	-	PUNCT
dpc-4976	2	346	severe	severe	ADJ
dpc-4976	2	347	psoriasis	psoriasis	NOUN
dpc-4976	2	348	:	:	PUNCT
dpc-4976	2	349	a	a	DET
dpc-4976	2	350	52	52	NUM
dpc-4976	2	351	-	-	PUNCT
dpc-4976	2	352	week	week	NOUN
dpc-4976	2	353	italian	italian	ADJ
dpc-4976	2	354	multicenter	multicenter	NOUN
dpc-4976	2	355	real	real	ADJ
dpc-4976	2	356	-	-	PUNCT
dpc-4976	2	357	life	life	NOUN
dpc-4976	2	358	lazio	lazio	NOUN
dpc-4976	2	359	experience	experience	NOUN
dpc-4976	2	360	.	.	PUNCT
dpc-4976	3	1	dermatol	dermatol	NOUN
dpc-4976	3	2	pract	pract	PROPN
dpc-4976	3	3	concept	concept	NOUN
dpc-4976	3	4	.	.	PUNCT
dpc-4976	4	1	2025;15(1):4976	2025;15(1):4976	PROPN
dpc-4976	4	2	.	.	PUNCT
dpc-4976	5	1	doi	doi	NOUN
dpc-4976	5	2	:	:	PUNCT
dpc-4976	5	3	 	 	SPACE
dpc-4976	5	4	https://doi.org/10.5826/dpc.1502a4976	https://doi.org/10.5826/dpc.1502a4976	NOUN
dpc-4976	5	5	accepted	accept	VERB
dpc-4976	5	6	:	:	PUNCT
dpc-4976	5	7	january	january	PROPN
dpc-4976	5	8	14	14	NUM
dpc-4976	5	9	,	,	PUNCT
dpc-4976	5	10	2025	2025	NUM
dpc-4976	5	11	;	;	PUNCT
dpc-4976	5	12	published	publish	VERB
dpc-4976	5	13	:	:	PUNCT
dpc-4976	6	1	april	april	PROPN
dpc-4976	6	2	2025	2025	NUM
dpc-4976	6	3	copyright	copyright	NOUN
dpc-4976	6	4	:	:	PUNCT
dpc-4976	7	1	©	©	PROPN
dpc-4976	7	2	2025	2025	NUM
dpc-4976	7	3	dattola	dattola	PROPN
dpc-4976	7	4	et	et	PROPN
dpc-4976	7	5	al	al	PROPN
dpc-4976	7	6	.	.	PUNCT
dpc-4976	8	1	this	this	PRON
dpc-4976	8	2	is	be	AUX
dpc-4976	8	3	an	an	DET
dpc-4976	8	4	open	open	ADJ
dpc-4976	8	5	-	-	PUNCT
dpc-4976	8	6	access	access	NOUN
dpc-4976	8	7	article	article	NOUN
dpc-4976	8	8	distributed	distribute	VERB
dpc-4976	8	9	under	under	ADP
dpc-4976	8	10	the	the	DET
dpc-4976	8	11	terms	term	NOUN
dpc-4976	8	12	of	of	ADP
dpc-4976	8	13	the	the	DET
dpc-4976	8	14	creative	creative	ADJ
dpc-4976	8	15	commons	common	NOUN
dpc-4976	8	16	attributionnoncommercial	attributionnoncommercial	ADJ
dpc-4976	8	17	license	license	NOUN
dpc-4976	8	18	(	(	PUNCT
dpc-4976	8	19	by	by	ADP
dpc-4976	8	20	-	-	PUNCT
dpc-4976	8	21	nc-4.0	nc-4.0	NOUN
dpc-4976	8	22	)	)	PUNCT
dpc-4976	8	23	,	,	PUNCT
dpc-4976	8	24	https://creativecommons.org/licenses/by-nc/4.0/	https://creativecommons.org/licenses/by-nc/4.0/	PROPN
dpc-4976	8	25	,	,	PUNCT
dpc-4976	8	26	which	which	PRON
dpc-4976	8	27	permits	permit	VERB
dpc-4976	8	28	unrestricted	unrestricted	ADJ
dpc-4976	8	29	noncommercial	noncommercial	ADJ
dpc-4976	8	30	use	use	NOUN
dpc-4976	8	31	,	,	PUNCT
dpc-4976	8	32	distribution	distribution	NOUN
dpc-4976	8	33	,	,	PUNCT
dpc-4976	8	34	and	and	CCONJ
dpc-4976	8	35	reproduction	reproduction	NOUN
dpc-4976	8	36	in	in	ADP
dpc-4976	8	37	any	any	DET
dpc-4976	8	38	medium	medium	NOUN
dpc-4976	8	39	,	,	PUNCT
dpc-4976	8	40	provided	provide	VERB
dpc-4976	8	41	the	the	DET
dpc-4976	8	42	original	original	ADJ
dpc-4976	8	43	authors	author	NOUN
dpc-4976	8	44	and	and	CCONJ
dpc-4976	8	45	source	source	NOUN
dpc-4976	8	46	are	be	AUX
dpc-4976	8	47	credited	credit	VERB
dpc-4976	8	48	.	.	PUNCT
dpc-4976	9	1	funding	funding	NOUN
dpc-4976	9	2	:	:	PUNCT
dpc-4976	9	3	none	none	NOUN
dpc-4976	9	4	.	.	PUNCT
dpc-4976	10	1	competing	compete	VERB
dpc-4976	10	2	interests	interest	NOUN
dpc-4976	10	3	:	:	PUNCT
dpc-4976	10	4	none	none	NOUN
dpc-4976	10	5	.	.	PUNCT
dpc-4976	11	1	authorship	authorship	NOUN
dpc-4976	11	2	:	:	PUNCT
dpc-4976	11	3	all	all	DET
dpc-4976	11	4	authors	author	NOUN
dpc-4976	11	5	have	have	AUX
dpc-4976	11	6	contributed	contribute	VERB
dpc-4976	11	7	significantly	significantly	ADV
dpc-4976	11	8	to	to	ADP
dpc-4976	11	9	this	this	DET
dpc-4976	11	10	publication	publication	NOUN
dpc-4976	11	11	.	.	PUNCT
dpc-4976	12	1	corresponding	correspond	VERB
dpc-4976	12	2	author	author	NOUN
dpc-4976	12	3	:	:	PUNCT
dpc-4976	12	4	annunziata	annunziata	PROPN
dpc-4976	12	5	dattola	dattola	PROPN
dpc-4976	12	6	,	,	PUNCT
dpc-4976	12	7	md	md	PROPN
dpc-4976	12	8	,	,	PUNCT
dpc-4976	12	9	phd	phd	NOUN
dpc-4976	12	10	,	,	PUNCT
dpc-4976	12	11	dermatology	dermatology	NOUN
dpc-4976	12	12	unit	unit	NOUN
dpc-4976	12	13	,	,	PUNCT
dpc-4976	12	14	university	university	PROPN
dpc-4976	12	15	of	of	ADP
dpc-4976	12	16	la	la	PROPN
dpc-4976	12	17	sapienza	sapienza	PROPN
dpc-4976	12	18	,	,	PUNCT
dpc-4976	12	19	rome	rome	PROPN
dpc-4976	12	20	.	.	PUNCT
dpc-4976	13	1	e	e	X
dpc-4976	13	2	-	-	NOUN
dpc-4976	13	3	mail	mail	NOUN
dpc-4976	13	4	:	:	PUNCT
dpc-4976	13	5	nancydattola@gmail.com	nancydattola@gmail.com	X
dpc-4976	13	6	2	2	NUM
dpc-4976	13	7	original	original	ADJ
dpc-4976	13	8	article	article	NOUN
dpc-4976	13	9	|	|	ADV
dpc-4976	13	10	dermatol	dermatol	ADJ
dpc-4976	13	11	pract	pract	NOUN
dpc-4976	13	12	concept	concept	NOUN
dpc-4976	13	13	.	.	PUNCT
dpc-4976	14	1	2025;15(1):4976	2025;15(1):4976	NUM
dpc-4976	14	2	introduction	introduction	NOUN
dpc-4976	14	3	psoriasis	psoriasis	NOUN
dpc-4976	14	4	(	(	PUNCT
dpc-4976	14	5	pso	pso	NOUN
dpc-4976	14	6	)	)	PUNCT
dpc-4976	14	7	is	be	AUX
dpc-4976	14	8	a	a	DET
dpc-4976	14	9	chronic	chronic	NOUN
dpc-4976	14	10	,	,	PUNCT
dpc-4976	14	11	immune	immune	NOUN
dpc-4976	14	12	-	-	PUNCT
dpc-4976	14	13	mediated	mediate	VERB
dpc-4976	14	14	skin	skin	NOUN
dpc-4976	14	15	disorder	disorder	NOUN
dpc-4976	14	16	that	that	PRON
dpc-4976	14	17	causes	cause	VERB
dpc-4976	14	18	the	the	DET
dpc-4976	14	19	rapid	rapid	ADJ
dpc-4976	14	20	proliferation	proliferation	NOUN
dpc-4976	14	21	of	of	ADP
dpc-4976	14	22	keratinocytes	keratinocyte	NOUN
dpc-4976	14	23	,	,	PUNCT
dpc-4976	14	24	leading	lead	VERB
dpc-4976	14	25	to	to	ADP
dpc-4976	14	26	thick	thick	ADJ
dpc-4976	14	27	,	,	PUNCT
dpc-4976	14	28	scaly	scaly	NOUN
dpc-4976	14	29	plaques	plaque	NOUN
dpc-4976	14	30	.	.	PUNCT
dpc-4976	15	1	it	it	PRON
dpc-4976	15	2	affects	affect	VERB
dpc-4976	15	3	2%–3	2%–3	NOUN
dpc-4976	15	4	%	%	NOUN
dpc-4976	15	5	of	of	ADP
dpc-4976	15	6	the	the	DET
dpc-4976	15	7	global	global	ADJ
dpc-4976	15	8	population	population	NOUN
dpc-4976	15	9	,	,	PUNCT
dpc-4976	15	10	with	with	ADP
dpc-4976	15	11	prevalence	prevalence	NOUN
dpc-4976	15	12	varying	vary	VERB
dpc-4976	15	13	across	across	ADP
dpc-4976	15	14	regions	region	NOUN
dpc-4976	15	15	.	.	PUNCT
dpc-4976	16	1	for	for	ADP
dpc-4976	16	2	example	example	NOUN
dpc-4976	16	3	,	,	PUNCT
dpc-4976	16	4	it	it	PRON
dpc-4976	16	5	reaches	reach	VERB
dpc-4976	16	6	2.5	2.5	NUM
dpc-4976	16	7	%	%	NOUN
dpc-4976	16	8	in	in	ADP
dpc-4976	16	9	western	western	ADJ
dpc-4976	16	10	europe	europe	PROPN
dpc-4976	16	11	but	but	CCONJ
dpc-4976	16	12	only	only	ADV
dpc-4976	16	13	0.17	0.17	NUM
dpc-4976	16	14	%	%	NOUN
dpc-4976	16	15	in	in	ADP
dpc-4976	16	16	east	east	PROPN
dpc-4976	16	17	asia	asia	PROPN
dpc-4976	17	1	[	[	X
dpc-4976	17	2	1	1	NUM
dpc-4976	17	3	-	-	SYM
dpc-4976	17	4	3	3	NUM
dpc-4976	17	5	]	]	PUNCT
dpc-4976	17	6	.	.	PUNCT
dpc-4976	18	1	pso	pso	NOUN
dpc-4976	18	2	is	be	AUX
dpc-4976	18	3	more	more	ADJ
dpc-4976	18	4	than	than	ADP
dpc-4976	18	5	a	a	DET
dpc-4976	18	6	skin	skin	NOUN
dpc-4976	18	7	condition	condition	NOUN
dpc-4976	18	8	;	;	PUNCT
dpc-4976	18	9	it	it	PRON
dpc-4976	18	10	is	be	AUX
dpc-4976	18	11	a	a	DET
dpc-4976	18	12	persistent	persistent	ADJ
dpc-4976	18	13	inflammatory	inflammatory	ADJ
dpc-4976	18	14	disease	disease	NOUN
dpc-4976	18	15	that	that	PRON
dpc-4976	18	16	significantly	significantly	ADV
dpc-4976	18	17	impacts	impact	VERB
dpc-4976	18	18	quality	quality	NOUN
dpc-4976	18	19	of	of	ADP
dpc-4976	18	20	life	life	NOUN
dpc-4976	18	21	(	(	PUNCT
dpc-4976	18	22	qol	qol	NOUN
dpc-4976	18	23	)	)	PUNCT
dpc-4976	18	24	.	.	PUNCT
dpc-4976	19	1	the	the	DET
dpc-4976	19	2	red	red	ADJ
dpc-4976	19	3	,	,	PUNCT
dpc-4976	19	4	scaly	scaly	NOUN
dpc-4976	19	5	plaques	plaque	NOUN
dpc-4976	19	6	,	,	PUNCT
dpc-4976	19	7	along	along	ADP
dpc-4976	19	8	with	with	ADP
dpc-4976	19	9	associated	associated	ADJ
dpc-4976	19	10	comorbidities	comorbiditie	NOUN
dpc-4976	19	11	,	,	PUNCT
dpc-4976	19	12	underscore	underscore	VERB
dpc-4976	19	13	the	the	DET
dpc-4976	19	14	systemic	systemic	ADJ
dpc-4976	19	15	nature	nature	NOUN
dpc-4976	19	16	of	of	ADP
dpc-4976	19	17	the	the	DET
dpc-4976	19	18	disorder	disorder	NOUN
dpc-4976	19	19	[	[	X
dpc-4976	19	20	4	4	NUM
dpc-4976	19	21	]	]	PUNCT
dpc-4976	19	22	.	.	PUNCT
dpc-4976	20	1	treatments	treatment	NOUN
dpc-4976	20	2	include	include	VERB
dpc-4976	20	3	topical	topical	ADJ
dpc-4976	20	4	therapies	therapy	NOUN
dpc-4976	20	5	,	,	PUNCT
dpc-4976	20	6	phototherapy	phototherapy	NOUN
dpc-4976	20	7	,	,	PUNCT
dpc-4976	20	8	and	and	CCONJ
dpc-4976	20	9	systemic	systemic	ADJ
dpc-4976	20	10	agents	agent	NOUN
dpc-4976	20	11	such	such	ADJ
dpc-4976	20	12	as	as	ADP
dpc-4976	20	13	methotrexate	methotrexate	NOUN
dpc-4976	20	14	,	,	PUNCT
dpc-4976	20	15	cyclosporine	cyclosporine	NOUN
dpc-4976	20	16	,	,	PUNCT
dpc-4976	20	17	and	and	CCONJ
dpc-4976	20	18	biologics	biologic	NOUN
dpc-4976	20	19	.	.	PUNCT
dpc-4976	21	1	biologic	biologic	NOUN
dpc-4976	21	2	therapies	therapy	NOUN
dpc-4976	21	3	target	target	VERB
dpc-4976	21	4	key	key	ADJ
dpc-4976	21	5	immune	immune	ADJ
dpc-4976	21	6	pathways	pathway	NOUN
dpc-4976	21	7	,	,	PUNCT
dpc-4976	21	8	including	include	VERB
dpc-4976	21	9	tumor	tumor	NOUN
dpc-4976	21	10	necrosis	necrosis	NOUN
dpc-4976	21	11	factor	factor	NOUN
dpc-4976	21	12	-	-	PUNCT
dpc-4976	21	13	alpha	alpha	NOUN
dpc-4976	21	14	(	(	PUNCT
dpc-4976	21	15	tnf	tnf	PROPN
dpc-4976	21	16	-	-	PUNCT
dpc-4976	21	17	α	α	NOUN
dpc-4976	21	18	)	)	PUNCT
dpc-4976	21	19	,	,	PUNCT
dpc-4976	21	20	interleukin-12/23	interleukin-12/23	ADJ
dpc-4976	21	21	(	(	PUNCT
dpc-4976	21	22	il-12/23	il-12/23	PROPN
dpc-4976	21	23	)	)	PUNCT
dpc-4976	21	24	,	,	PUNCT
dpc-4976	21	25	and	and	CCONJ
dpc-4976	21	26	interleukin-17	interleukin-17	PROPN
dpc-4976	21	27	(	(	PUNCT
dpc-4976	21	28	il-17	il-17	NUM
dpc-4976	21	29	)	)	PUNCT
dpc-4976	21	30	,	,	PUNCT
dpc-4976	21	31	to	to	PART
dpc-4976	21	32	modulate	modulate	VERB
dpc-4976	21	33	the	the	DET
dpc-4976	21	34	immune	immune	ADJ
dpc-4976	21	35	system	system	NOUN
dpc-4976	21	36	and	and	CCONJ
dpc-4976	21	37	reduce	reduce	VERB
dpc-4976	21	38	inflammation	inflammation	NOUN
dpc-4976	21	39	[	[	X
dpc-4976	21	40	1,2	1,2	NUM
dpc-4976	21	41	]	]	PUNCT
dpc-4976	21	42	.	.	PUNCT
dpc-4976	22	1	the	the	DET
dpc-4976	22	2	pathogenesis	pathogenesis	NOUN
dpc-4976	22	3	of	of	ADP
dpc-4976	22	4	psoriasis	psoriasis	NOUN
dpc-4976	22	5	involves	involve	VERB
dpc-4976	22	6	genetic	genetic	ADJ
dpc-4976	22	7	,	,	PUNCT
dpc-4976	22	8	environmental	environmental	ADJ
dpc-4976	22	9	,	,	PUNCT
dpc-4976	22	10	and	and	CCONJ
dpc-4976	22	11	immune	immune	ADJ
dpc-4976	22	12	factors	factor	NOUN
dpc-4976	22	13	.	.	PUNCT
dpc-4976	23	1	a	a	DET
dpc-4976	23	2	key	key	ADJ
dpc-4976	23	3	driver	driver	NOUN
dpc-4976	23	4	is	be	AUX
dpc-4976	23	5	the	the	DET
dpc-4976	23	6	overactivation	overactivation	NOUN
dpc-4976	23	7	of	of	ADP
dpc-4976	23	8	t	t	PROPN
dpc-4976	23	9	-	-	PUNCT
dpc-4976	23	10	helper	helper	NOUN
dpc-4976	23	11	17	17	NUM
dpc-4976	23	12	(	(	PUNCT
dpc-4976	23	13	th17	th17	NOUN
dpc-4976	23	14	)	)	PUNCT
dpc-4976	23	15	cells	cell	NOUN
dpc-4976	23	16	,	,	PUNCT
dpc-4976	23	17	which	which	PRON
dpc-4976	23	18	release	release	VERB
dpc-4976	23	19	pro	pro	ADJ
dpc-4976	23	20	-	-	ADJ
dpc-4976	23	21	inflammatory	inflammatory	ADJ
dpc-4976	23	22	cytokines	cytokine	NOUN
dpc-4976	23	23	like	like	ADP
dpc-4976	23	24	il-17a	il-17a	PROPN
dpc-4976	23	25	and	and	CCONJ
dpc-4976	23	26	il-17f	il-17f	NOUN
dpc-4976	23	27	.	.	PUNCT
dpc-4976	24	1	these	these	DET
dpc-4976	24	2	cytokines	cytokine	NOUN
dpc-4976	24	3	induce	induce	VERB
dpc-4976	24	4	keratinocyte	keratinocyte	NOUN
dpc-4976	24	5	proliferation	proliferation	NOUN
dpc-4976	24	6	and	and	CCONJ
dpc-4976	24	7	inflammation	inflammation	NOUN
dpc-4976	24	8	,	,	PUNCT
dpc-4976	24	9	creating	create	VERB
dpc-4976	24	10	the	the	DET
dpc-4976	24	11	characteristic	characteristic	ADJ
dpc-4976	24	12	plaques	plaque	NOUN
dpc-4976	24	13	of	of	ADP
dpc-4976	24	14	psoriasis	psoriasis	NOUN
dpc-4976	24	15	.	.	PUNCT
dpc-4976	25	1	targeting	target	VERB
dpc-4976	25	2	the	the	DET
dpc-4976	25	3	il-17	il-17	NUM
dpc-4976	25	4	pathway	pathway	NOUN
dpc-4976	25	5	,	,	PUNCT
dpc-4976	25	6	therefore	therefore	ADV
dpc-4976	25	7	,	,	PUNCT
dpc-4976	25	8	is	be	AUX
dpc-4976	25	9	central	central	ADJ
dpc-4976	25	10	to	to	ADP
dpc-4976	25	11	treatment	treatment	NOUN
dpc-4976	25	12	strategies	strategy	NOUN
dpc-4976	25	13	[	[	X
dpc-4976	25	14	5,6	5,6	NUM
dpc-4976	25	15	]	]	PUNCT
dpc-4976	25	16	.	.	PUNCT
dpc-4976	26	1	bimekizumab	bimekizumab	PROPN
dpc-4976	26	2	is	be	AUX
dpc-4976	26	3	a	a	DET
dpc-4976	26	4	novel	novel	ADJ
dpc-4976	26	5	monoclonal	monoclonal	NOUN
dpc-4976	26	6	antibody	antibody	NOUN
dpc-4976	26	7	that	that	PRON
dpc-4976	26	8	uniquely	uniquely	ADV
dpc-4976	26	9	targets	target	VERB
dpc-4976	26	10	both	both	CCONJ
dpc-4976	26	11	il-17a	il-17a	PROPN
dpc-4976	26	12	and	and	CCONJ
dpc-4976	26	13	il-17f	il-17f	PROPN
dpc-4976	26	14	,	,	PUNCT
dpc-4976	26	15	cytokines	cytokine	VERB
dpc-4976	26	16	that	that	PRON
dpc-4976	26	17	are	be	AUX
dpc-4976	26	18	crucial	crucial	ADJ
dpc-4976	26	19	in	in	ADP
dpc-4976	26	20	the	the	DET
dpc-4976	26	21	pathogenesis	pathogenesis	NOUN
dpc-4976	26	22	of	of	ADP
dpc-4976	26	23	psoriasis	psoriasis	NOUN
dpc-4976	26	24	.	.	PUNCT
dpc-4976	27	1	by	by	ADP
dpc-4976	27	2	inhibiting	inhibit	VERB
dpc-4976	27	3	these	these	DET
dpc-4976	27	4	two	two	NUM
dpc-4976	27	5	cytokines	cytokine	NOUN
dpc-4976	27	6	,	,	PUNCT
dpc-4976	27	7	bimekizumab	bimekizumab	NOUN
dpc-4976	27	8	offers	offer	VERB
dpc-4976	27	9	a	a	DET
dpc-4976	27	10	broader	broad	ADJ
dpc-4976	27	11	blockade	blockade	NOUN
dpc-4976	27	12	of	of	ADP
dpc-4976	27	13	the	the	DET
dpc-4976	27	14	il-17	il-17	ADJ
dpc-4976	27	15	pathway	pathway	NOUN
dpc-4976	27	16	than	than	ADP
dpc-4976	27	17	other	other	ADJ
dpc-4976	27	18	il-17	il-17	ADP
dpc-4976	27	19	inhibitors	inhibitor	NOUN
dpc-4976	27	20	that	that	PRON
dpc-4976	27	21	target	target	VERB
dpc-4976	27	22	only	only	ADV
dpc-4976	27	23	il-17a	il-17a	PROPN
dpc-4976	27	24	.	.	PUNCT
dpc-4976	28	1	this	this	DET
dpc-4976	28	2	dual	dual	ADJ
dpc-4976	28	3	inhibition	inhibition	NOUN
dpc-4976	28	4	is	be	AUX
dpc-4976	28	5	hypothesized	hypothesize	VERB
dpc-4976	28	6	to	to	PART
dpc-4976	28	7	provide	provide	VERB
dpc-4976	28	8	superior	superior	ADJ
dpc-4976	28	9	efficacy	efficacy	NOUN
dpc-4976	28	10	in	in	ADP
dpc-4976	28	11	reducing	reduce	VERB
dpc-4976	28	12	the	the	DET
dpc-4976	28	13	inflammatory	inflammatory	ADJ
dpc-4976	28	14	burden	burden	NOUN
dpc-4976	28	15	and	and	CCONJ
dpc-4976	28	16	clinical	clinical	ADJ
dpc-4976	28	17	symptoms	symptom	NOUN
dpc-4976	28	18	of	of	ADP
dpc-4976	28	19	psoriasis	psoriasis	NOUN
dpc-4976	28	20	.	.	PUNCT
dpc-4976	29	1	clinical	clinical	ADJ
dpc-4976	29	2	trials	trial	NOUN
dpc-4976	29	3	have	have	AUX
dpc-4976	29	4	demonstrated	demonstrate	VERB
dpc-4976	29	5	that	that	PRON
dpc-4976	29	6	bimekizumab	bimekizumab	NOUN
dpc-4976	29	7	significantly	significantly	ADV
dpc-4976	29	8	improves	improve	VERB
dpc-4976	29	9	psoriasis	psoriasis	NOUN
dpc-4976	29	10	symptoms	symptom	NOUN
dpc-4976	29	11	,	,	PUNCT
dpc-4976	29	12	achieving	achieve	VERB
dpc-4976	29	13	higher	high	ADJ
dpc-4976	29	14	rates	rate	NOUN
dpc-4976	29	15	of	of	ADP
dpc-4976	29	16	skin	skin	NOUN
dpc-4976	29	17	clearance	clearance	NOUN
dpc-4976	29	18	compared	compare	VERB
dpc-4976	29	19	to	to	ADP
dpc-4976	29	20	placebo	placebo	NOUN
dpc-4976	29	21	and	and	CCONJ
dpc-4976	29	22	active	active	ADJ
dpc-4976	29	23	comparators	comparator	NOUN
dpc-4976	29	24	such	such	ADJ
dpc-4976	29	25	as	as	ADP
dpc-4976	29	26	secukinumab	secukinumab	NOUN
dpc-4976	29	27	,	,	PUNCT
dpc-4976	29	28	adalimumab	adalimumab	NOUN
dpc-4976	29	29	,	,	PUNCT
dpc-4976	29	30	and	and	CCONJ
dpc-4976	29	31	ustekinumab	ustekinumab	NOUN
dpc-4976	29	32	.	.	PUNCT
dpc-4976	30	1	for	for	ADP
dpc-4976	30	2	example	example	NOUN
dpc-4976	30	3	,	,	PUNCT
dpc-4976	30	4	in	in	ADP
dpc-4976	30	5	the	the	DET
dpc-4976	30	6	be	be	AUX
dpc-4976	30	7	ready	ready	ADJ
dpc-4976	30	8	,	,	PUNCT
dpc-4976	30	9	be	be	AUX
dpc-4976	30	10	sure	sure	ADJ
dpc-4976	30	11	,	,	PUNCT
dpc-4976	30	12	and	and	CCONJ
dpc-4976	30	13	be	be	AUX
dpc-4976	30	14	vivid	vivid	ADJ
dpc-4976	30	15	phase	phase	NOUN
dpc-4976	30	16	3	3	NUM
dpc-4976	30	17	trials	trial	NOUN
dpc-4976	30	18	,	,	PUNCT
dpc-4976	30	19	bimekizumab	bimekizumab	PROPN
dpc-4976	30	20	showed	show	VERB
dpc-4976	30	21	superior	superior	ADJ
dpc-4976	30	22	clinical	clinical	ADJ
dpc-4976	30	23	efficacy	efficacy	NOUN
dpc-4976	30	24	,	,	PUNCT
dpc-4976	30	25	with	with	ADP
dpc-4976	30	26	many	many	ADJ
dpc-4976	30	27	patients	patient	NOUN
dpc-4976	30	28	achieving	achieve	VERB
dpc-4976	30	29	complete	complete	ADJ
dpc-4976	30	30	skin	skin	NOUN
dpc-4976	30	31	clearance	clearance	NOUN
dpc-4976	30	32	(	(	PUNCT
dpc-4976	30	33	pasi	pasi	NOUN
dpc-4976	30	34	100	100	NUM
dpc-4976	30	35	)	)	PUNCT
dpc-4976	30	36	by	by	ADP
dpc-4976	30	37	week	week	NOUN
dpc-4976	30	38	16	16	NUM
dpc-4976	30	39	of	of	ADP
dpc-4976	30	40	treatment	treatment	NOUN
dpc-4976	30	41	[	[	X
dpc-4976	30	42	7	7	NUM
dpc-4976	30	43	]	]	PUNCT
dpc-4976	30	44	.	.	PUNCT
dpc-4976	31	1	objectives	objective	VERB
dpc-4976	31	2	the	the	DET
dpc-4976	31	3	aim	aim	NOUN
dpc-4976	31	4	of	of	ADP
dpc-4976	31	5	this	this	DET
dpc-4976	31	6	study	study	NOUN
dpc-4976	31	7	was	be	AUX
dpc-4976	31	8	to	to	PART
dpc-4976	31	9	evaluate	evaluate	VERB
dpc-4976	31	10	the	the	DET
dpc-4976	31	11	clinical	clinical	ADJ
dpc-4976	31	12	efficacy	efficacy	NOUN
dpc-4976	31	13	and	and	CCONJ
dpc-4976	31	14	safety	safety	NOUN
dpc-4976	31	15	of	of	ADP
dpc-4976	31	16	bimekizumab	bimekizumab	NOUN
dpc-4976	31	17	in	in	ADP
dpc-4976	31	18	patients	patient	NOUN
dpc-4976	31	19	with	with	ADP
dpc-4976	31	20	moderate	moderate	ADJ
dpc-4976	31	21	-	-	PUNCT
dpc-4976	31	22	to	to	ADP
dpc-4976	31	23	-	-	PUNCT
dpc-4976	31	24	severe	severe	ADJ
dpc-4976	31	25	psoriasis	psoriasis	NOUN
dpc-4976	31	26	over	over	ADP
dpc-4976	31	27	a	a	DET
dpc-4976	31	28	follow	follow	NOUN
dpc-4976	31	29	-	-	PUNCT
dpc-4976	31	30	up	up	NOUN
dpc-4976	31	31	period	period	NOUN
dpc-4976	31	32	of	of	ADP
dpc-4976	31	33	52	52	NUM
dpc-4976	31	34	weeks	week	NOUN
dpc-4976	31	35	.	.	PUNCT
dpc-4976	32	1	methods	method	NOUN
dpc-4976	32	2	study	study	PROPN
dpc-4976	32	3	design	design	VERB
dpc-4976	32	4	a	a	DET
dpc-4976	32	5	retrospective	retrospective	ADJ
dpc-4976	32	6	analysis	analysis	NOUN
dpc-4976	32	7	of	of	ADP
dpc-4976	32	8	real	real	ADJ
dpc-4976	32	9	-	-	PUNCT
dpc-4976	32	10	world	world	NOUN
dpc-4976	32	11	data	datum	NOUN
dpc-4976	32	12	was	be	AUX
dpc-4976	32	13	conducted	conduct	VERB
dpc-4976	32	14	on	on	ADP
dpc-4976	32	15	132	132	NUM
dpc-4976	32	16	patients	patient	NOUN
dpc-4976	32	17	,	,	PUNCT
dpc-4976	32	18	drawing	draw	VERB
dpc-4976	32	19	on	on	ADP
dpc-4976	32	20	the	the	DET
dpc-4976	32	21	clinical	clinical	ADJ
dpc-4976	32	22	expertise	expertise	NOUN
dpc-4976	32	23	of	of	ADP
dpc-4976	32	24	healthcare	healthcare	NOUN
dpc-4976	32	25	facilities	facility	NOUN
dpc-4976	32	26	in	in	ADP
dpc-4976	32	27	the	the	DET
dpc-4976	32	28	lazio	lazio	PROPN
dpc-4976	32	29	region	region	PROPN
dpc-4976	32	30	,	,	PUNCT
dpc-4976	32	31	italy	italy	PROPN
dpc-4976	32	32	.	.	PUNCT
dpc-4976	33	1	data	datum	NOUN
dpc-4976	33	2	collection	collection	NOUN
dpc-4976	33	3	took	take	VERB
dpc-4976	33	4	place	place	NOUN
dpc-4976	33	5	across	across	ADP
dpc-4976	33	6	eight	eight	NUM
dpc-4976	33	7	medical	medical	ADJ
dpc-4976	33	8	centers	center	NOUN
dpc-4976	33	9	,	,	PUNCT
dpc-4976	33	10	detailed	detail	VERB
dpc-4976	33	11	in	in	ADP
dpc-4976	33	12	table	table	NOUN
dpc-4976	33	13	1	1	NUM
dpc-4976	33	14	.	.	PUNCT
dpc-4976	34	1	outcome	outcome	NOUN
dpc-4976	34	2	measures	measure	NOUN
dpc-4976	34	3	the	the	DET
dpc-4976	34	4	primary	primary	ADJ
dpc-4976	34	5	endpoint	endpoint	NOUN
dpc-4976	34	6	consisted	consist	VERB
dpc-4976	34	7	in	in	ADP
dpc-4976	34	8	assessing	assess	VERB
dpc-4976	34	9	the	the	DET
dpc-4976	34	10	efficacy	efficacy	NOUN
dpc-4976	34	11	of	of	ADP
dpc-4976	34	12	bimekizumab	bimekizumab	NOUN
dpc-4976	34	13	over	over	ADP
dpc-4976	34	14	time	time	NOUN
dpc-4976	34	15	and	and	CCONJ
dpc-4976	34	16	according	accord	VERB
dpc-4976	34	17	to	to	ADP
dpc-4976	34	18	different	different	ADJ
dpc-4976	34	19	body	body	NOUN
dpc-4976	34	20	areas	area	NOUN
dpc-4976	34	21	by	by	ADP
dpc-4976	34	22	evaluating	evaluate	VERB
dpc-4976	34	23	the	the	DET
dpc-4976	34	24	improvement	improvement	NOUN
dpc-4976	34	25	in	in	ADP
dpc-4976	34	26	psoriasis	psoriasis	NOUN
dpc-4976	34	27	symptoms	symptom	NOUN
dpc-4976	34	28	using	use	VERB
dpc-4976	34	29	introduction	introduction	NOUN
dpc-4976	34	30	:	:	PUNCT
dpc-4976	34	31	psoriasis	psoriasis	NOUN
dpc-4976	34	32	significantly	significantly	ADV
dpc-4976	34	33	impacts	impact	VERB
dpc-4976	34	34	a	a	DET
dpc-4976	34	35	patient	patient	NOUN
dpc-4976	34	36	’s	’s	PART
dpc-4976	34	37	quality	quality	NOUN
dpc-4976	34	38	of	of	ADP
dpc-4976	34	39	life	life	NOUN
dpc-4976	34	40	(	(	PUNCT
dpc-4976	34	41	qol	qol	NOUN
dpc-4976	34	42	)	)	PUNCT
dpc-4976	34	43	.	.	PUNCT
dpc-4976	35	1	bimekizumab	bimekizumab	NOUN
dpc-4976	35	2	targets	target	NOUN
dpc-4976	35	3	il-17a	il-17a	PROPN
dpc-4976	35	4	and	and	CCONJ
dpc-4976	35	5	il-17f	il-17f	NOUN
dpc-4976	35	6	,	,	PUNCT
dpc-4976	35	7	offering	offer	VERB
dpc-4976	35	8	a	a	DET
dpc-4976	35	9	broader	broad	ADJ
dpc-4976	35	10	blockade	blockade	NOUN
dpc-4976	35	11	of	of	ADP
dpc-4976	35	12	the	the	DET
dpc-4976	35	13	il-17	il-17	NUM
dpc-4976	35	14	pathway	pathway	NOUN
dpc-4976	35	15	compared	compare	VERB
dpc-4976	35	16	to	to	ADP
dpc-4976	35	17	other	other	ADJ
dpc-4976	35	18	il-17	il-17	ADP
dpc-4976	35	19	inhibitors	inhibitor	NOUN
dpc-4976	35	20	.	.	PUNCT
dpc-4976	36	1	objectives	objective	NOUN
dpc-4976	36	2	:	:	PUNCT
dpc-4976	36	3	this	this	DET
dpc-4976	36	4	study	study	NOUN
dpc-4976	36	5	evaluated	evaluate	VERB
dpc-4976	36	6	the	the	DET
dpc-4976	36	7	clinical	clinical	ADJ
dpc-4976	36	8	efficacy	efficacy	NOUN
dpc-4976	36	9	of	of	ADP
dpc-4976	36	10	bimekizumab	bimekizumab	NOUN
dpc-4976	36	11	in	in	ADP
dpc-4976	36	12	bio	bio	ADJ
dpc-4976	36	13	-	-	ADJ
dpc-4976	36	14	naive	naive	ADJ
dpc-4976	36	15	and	and	CCONJ
dpc-4976	36	16	bioexperienced	bioexperience	VERB
dpc-4976	36	17	patients	patient	NOUN
dpc-4976	36	18	with	with	ADP
dpc-4976	36	19	moderate	moderate	ADJ
dpc-4976	36	20	-	-	PUNCT
dpc-4976	36	21	to	to	ADP
dpc-4976	36	22	-	-	PUNCT
dpc-4976	36	23	severe	severe	ADJ
dpc-4976	36	24	psoriasis	psoriasis	NOUN
dpc-4976	36	25	over	over	ADP
dpc-4976	36	26	a	a	DET
dpc-4976	36	27	52	52	NUM
dpc-4976	36	28	-	-	PUNCT
dpc-4976	36	29	week	week	NOUN
dpc-4976	36	30	period	period	NOUN
dpc-4976	36	31	,	,	PUNCT
dpc-4976	36	32	with	with	ADP
dpc-4976	36	33	a	a	DET
dpc-4976	36	34	focus	focus	NOUN
dpc-4976	36	35	on	on	ADP
dpc-4976	36	36	improvements	improvement	NOUN
dpc-4976	36	37	across	across	ADP
dpc-4976	36	38	different	different	ADJ
dpc-4976	36	39	body	body	NOUN
dpc-4976	36	40	areas	area	NOUN
dpc-4976	36	41	and	and	CCONJ
dpc-4976	36	42	qol	qol	PROPN
dpc-4976	36	43	.	.	PUNCT
dpc-4976	37	1	methods	method	NOUN
dpc-4976	37	2	:	:	PUNCT
dpc-4976	37	3	a	a	DET
dpc-4976	37	4	retrospective	retrospective	ADJ
dpc-4976	37	5	analysis	analysis	NOUN
dpc-4976	37	6	of	of	ADP
dpc-4976	37	7	real	real	ADJ
dpc-4976	37	8	-	-	PUNCT
dpc-4976	37	9	world	world	NOUN
dpc-4976	37	10	data	datum	NOUN
dpc-4976	37	11	was	be	AUX
dpc-4976	37	12	conducted	conduct	VERB
dpc-4976	37	13	on	on	ADP
dpc-4976	37	14	132	132	NUM
dpc-4976	37	15	patients	patient	NOUN
dpc-4976	37	16	from	from	ADP
dpc-4976	37	17	eight	eight	NUM
dpc-4976	37	18	medical	medical	ADJ
dpc-4976	37	19	centers	center	NOUN
dpc-4976	37	20	.	.	PUNCT
dpc-4976	38	1	efficacy	efficacy	NOUN
dpc-4976	38	2	was	be	AUX
dpc-4976	38	3	assessed	assess	VERB
dpc-4976	38	4	using	use	VERB
dpc-4976	38	5	pasi	pasi	NOUN
dpc-4976	38	6	scores	score	NOUN
dpc-4976	38	7	,	,	PUNCT
dpc-4976	38	8	at	at	ADP
dpc-4976	38	9	baseline	baseline	NOUN
dpc-4976	38	10	and	and	CCONJ
dpc-4976	38	11	at	at	ADP
dpc-4976	38	12	weeks	week	NOUN
dpc-4976	38	13	4	4	NUM
dpc-4976	38	14	,	,	PUNCT
dpc-4976	38	15	16	16	NUM
dpc-4976	38	16	,	,	PUNCT
dpc-4976	38	17	24	24	NUM
dpc-4976	38	18	,	,	PUNCT
dpc-4976	38	19	and	and	CCONJ
dpc-4976	38	20	52	52	NUM
dpc-4976	38	21	,	,	PUNCT
dpc-4976	38	22	and	and	CCONJ
dpc-4976	38	23	dlqi	dlqi	ADJ
dpc-4976	38	24	scores	score	NOUN
dpc-4976	38	25	.	.	PUNCT
dpc-4976	39	1	patients	patient	NOUN
dpc-4976	39	2	were	be	AUX
dpc-4976	39	3	categorized	categorize	VERB
dpc-4976	39	4	based	base	VERB
dpc-4976	39	5	on	on	ADP
dpc-4976	39	6	prior	prior	ADJ
dpc-4976	39	7	biologic	biologic	ADJ
dpc-4976	39	8	treatment	treatment	NOUN
dpc-4976	39	9	experience	experience	NOUN
dpc-4976	39	10	.	.	PUNCT
dpc-4976	40	1	results	result	NOUN
dpc-4976	40	2	:	:	PUNCT
dpc-4976	40	3	the	the	DET
dpc-4976	40	4	mean	mean	ADJ
dpc-4976	40	5	pasi	pasi	NOUN
dpc-4976	40	6	score	score	NOUN
dpc-4976	40	7	decreased	decrease	VERB
dpc-4976	40	8	for	for	ADP
dpc-4976	40	9	all	all	DET
dpc-4976	40	10	patients	patient	NOUN
dpc-4976	40	11	,	,	PUNCT
dpc-4976	40	12	from	from	ADP
dpc-4976	40	13	14.41	14.41	NUM
dpc-4976	40	14	at	at	ADP
dpc-4976	40	15	baseline	baseline	NOUN
dpc-4976	40	16	to	to	ADP
dpc-4976	40	17	0.18	0.18	NUM
dpc-4976	40	18	at	at	ADP
dpc-4976	40	19	week	week	NOUN
dpc-4976	40	20	52	52	NUM
dpc-4976	40	21	,	,	PUNCT
dpc-4976	40	22	indicating	indicate	VERB
dpc-4976	40	23	substantial	substantial	ADJ
dpc-4976	40	24	improvement	improvement	NOUN
dpc-4976	40	25	.	.	PUNCT
dpc-4976	41	1	area	area	NOUN
dpc-4976	41	2	-	-	PUNCT
dpc-4976	41	3	specific	specific	ADJ
dpc-4976	41	4	pasi	pasi	NOUN
dpc-4976	41	5	subscores	subscore	NOUN
dpc-4976	41	6	showed	show	VERB
dpc-4976	41	7	significant	significant	ADJ
dpc-4976	41	8	reductions	reduction	NOUN
dpc-4976	41	9	:	:	PUNCT
dpc-4976	41	10	head	head	NOUN
dpc-4976	41	11	(	(	PUNCT
dpc-4976	41	12	3.24	3.24	NUM
dpc-4976	41	13	to	to	ADP
dpc-4976	41	14	0.13	0.13	NUM
dpc-4976	41	15	)	)	PUNCT
dpc-4976	41	16	,	,	PUNCT
dpc-4976	41	17	upper	upper	ADJ
dpc-4976	41	18	limb	limb	NOUN
dpc-4976	41	19	(	(	PUNCT
dpc-4976	41	20	8.49	8.49	NUM
dpc-4976	41	21	to	to	ADP
dpc-4976	41	22	0	0	NUM
dpc-4976	41	23	)	)	PUNCT
dpc-4976	41	24	,	,	PUNCT
dpc-4976	41	25	trunk	trunk	NOUN
dpc-4976	41	26	(	(	PUNCT
dpc-4976	41	27	8.35	8.35	NUM
dpc-4976	41	28	to	to	ADP
dpc-4976	41	29	0.03	0.03	NUM
dpc-4976	41	30	)	)	PUNCT
dpc-4976	41	31	,	,	PUNCT
dpc-4976	41	32	and	and	CCONJ
dpc-4976	41	33	lower	low	ADJ
dpc-4976	41	34	limb	limb	NOUN
dpc-4976	41	35	(	(	PUNCT
dpc-4976	41	36	8.61	8.61	NUM
dpc-4976	41	37	to	to	PART
dpc-4976	41	38	0.12	0.12	NUM
dpc-4976	41	39	)	)	PUNCT
dpc-4976	41	40	.	.	PUNCT
dpc-4976	42	1	complete	complete	ADJ
dpc-4976	42	2	skin	skin	NOUN
dpc-4976	42	3	clearance	clearance	NOUN
dpc-4976	42	4	was	be	AUX
dpc-4976	42	5	achieved	achieve	VERB
dpc-4976	42	6	by	by	ADP
dpc-4976	42	7	week	week	NOUN
dpc-4976	42	8	16	16	NUM
dpc-4976	42	9	in	in	ADP
dpc-4976	42	10	the	the	DET
dpc-4976	42	11	majority	majority	NOUN
dpc-4976	42	12	of	of	ADP
dpc-4976	42	13	patients	patient	NOUN
dpc-4976	42	14	:	:	PUNCT
dpc-4976	42	15	85	85	NUM
dpc-4976	42	16	%	%	NOUN
dpc-4976	42	17	achieved	achieve	VERB
dpc-4976	42	18	complete	complete	ADJ
dpc-4976	42	19	skin	skin	NOUN
dpc-4976	42	20	clearance	clearance	NOUN
dpc-4976	42	21	on	on	ADP
dpc-4976	42	22	the	the	DET
dpc-4976	42	23	head	head	NOUN
dpc-4976	42	24	,	,	PUNCT
dpc-4976	42	25	90	90	NUM
dpc-4976	42	26	%	%	NOUN
dpc-4976	42	27	on	on	ADP
dpc-4976	42	28	upper	upper	ADJ
dpc-4976	42	29	limbs	limb	NOUN
dpc-4976	42	30	,	,	PUNCT
dpc-4976	42	31	and	and	CCONJ
dpc-4976	42	32	94	94	NUM
dpc-4976	42	33	%	%	NOUN
dpc-4976	42	34	on	on	ADP
dpc-4976	42	35	both	both	CCONJ
dpc-4976	42	36	trunk	trunk	NOUN
dpc-4976	42	37	and	and	CCONJ
dpc-4976	42	38	lower	low	ADJ
dpc-4976	42	39	limbs	limb	NOUN
dpc-4976	42	40	.	.	PUNCT
dpc-4976	43	1	dlqi	dlqi	PROPN
dpc-4976	43	2	scores	score	NOUN
dpc-4976	43	3	significantly	significantly	ADV
dpc-4976	43	4	improved	improve	VERB
dpc-4976	43	5	,	,	PUNCT
dpc-4976	43	6	from	from	ADP
dpc-4976	43	7	13.57	13.57	NUM
dpc-4976	43	8	at	at	ADP
dpc-4976	43	9	baseline	baseline	NOUN
dpc-4976	43	10	to	to	ADP
dpc-4976	43	11	0.86	0.86	NUM
dpc-4976	43	12	at	at	ADP
dpc-4976	43	13	week	week	NOUN
dpc-4976	43	14	16	16	NUM
dpc-4976	43	15	,	,	PUNCT
dpc-4976	43	16	highlighting	highlight	VERB
dpc-4976	43	17	the	the	DET
dpc-4976	43	18	early	early	ADJ
dpc-4976	43	19	positive	positive	ADJ
dpc-4976	43	20	impact	impact	NOUN
dpc-4976	43	21	of	of	ADP
dpc-4976	43	22	bimekizumab	bimekizumab	NOUN
dpc-4976	43	23	in	in	ADP
dpc-4976	43	24	improving	improve	VERB
dpc-4976	43	25	qol	qol	NOUN
dpc-4976	43	26	.	.	PUNCT
dpc-4976	44	1	when	when	SCONJ
dpc-4976	44	2	comparing	compare	VERB
dpc-4976	44	3	pasi	pasi	NOUN
dpc-4976	44	4	scores	score	NOUN
dpc-4976	44	5	between	between	ADP
dpc-4976	44	6	bio	bio	NOUN
dpc-4976	44	7	-	-	ADJ
dpc-4976	44	8	naive	naive	ADJ
dpc-4976	44	9	and	and	CCONJ
dpc-4976	44	10	bio	bio	ADJ
dpc-4976	44	11	-	-	ADJ
dpc-4976	44	12	experienced	experienced	ADJ
dpc-4976	44	13	patients	patient	NOUN
dpc-4976	44	14	,	,	PUNCT
dpc-4976	44	15	no	no	DET
dpc-4976	44	16	significant	significant	ADJ
dpc-4976	44	17	difference	difference	NOUN
dpc-4976	44	18	was	be	AUX
dpc-4976	44	19	found	find	VERB
dpc-4976	44	20	.	.	PUNCT
dpc-4976	45	1	conclusions	conclusion	NOUN
dpc-4976	45	2	:	:	PUNCT
dpc-4976	45	3	bimekizumab	bimekizumab	NOUN
dpc-4976	45	4	demonstrates	demonstrate	VERB
dpc-4976	45	5	significant	significant	ADJ
dpc-4976	45	6	efficacy	efficacy	NOUN
dpc-4976	45	7	in	in	ADP
dpc-4976	45	8	reducing	reduce	VERB
dpc-4976	45	9	psoriasis	psoriasis	NOUN
dpc-4976	45	10	severity	severity	NOUN
dpc-4976	45	11	across	across	ADP
dpc-4976	45	12	different	different	ADJ
dpc-4976	45	13	body	body	NOUN
dpc-4976	45	14	areas	area	NOUN
dpc-4976	45	15	and	and	CCONJ
dpc-4976	45	16	improving	improve	VERB
dpc-4976	45	17	qol	qol	NOUN
dpc-4976	45	18	over	over	ADP
dpc-4976	45	19	a	a	DET
dpc-4976	45	20	52	52	NUM
dpc-4976	45	21	-	-	PUNCT
dpc-4976	45	22	week	week	NOUN
dpc-4976	45	23	period	period	NOUN
dpc-4976	45	24	.	.	PUNCT
dpc-4976	46	1	these	these	DET
dpc-4976	46	2	findings	finding	NOUN
dpc-4976	46	3	support	support	VERB
dpc-4976	46	4	this	this	DET
dpc-4976	46	5	robust	robust	ADJ
dpc-4976	46	6	treatment	treatment	NOUN
dpc-4976	46	7	option	option	NOUN
dpc-4976	46	8	for	for	ADP
dpc-4976	46	9	moderate	moderate	ADJ
dpc-4976	46	10	-	-	PUNCT
dpc-4976	46	11	to	to	ADP
dpc-4976	46	12	-	-	PUNCT
dpc-4976	46	13	severe	severe	ADJ
dpc-4976	46	14	psoriasis	psoriasis	NOUN
dpc-4976	46	15	.	.	PUNCT
dpc-4976	47	1	abstract	abstract	ADJ
dpc-4976	47	2	original	original	ADJ
dpc-4976	47	3	article	article	NOUN
dpc-4976	47	4	|	|	ADV
dpc-4976	47	5	dermatol	dermatol	ADJ
dpc-4976	47	6	pract	pract	NOUN
dpc-4976	47	7	concept	concept	NOUN
dpc-4976	47	8	.	.	PUNCT
dpc-4976	48	1	2025;15(1):4976	2025;15(1):4976	NUM
dpc-4976	48	2	3	3	NUM
dpc-4976	48	3	the	the	DET
dpc-4976	48	4	psoriasis	psoriasis	NOUN
dpc-4976	48	5	area	area	NOUN
dpc-4976	48	6	and	and	CCONJ
dpc-4976	48	7	severity	severity	NOUN
dpc-4976	48	8	index	index	NOUN
dpc-4976	48	9	(	(	PUNCT
dpc-4976	48	10	pasi	pasi	NOUN
dpc-4976	48	11	)	)	PUNCT
dpc-4976	48	12	scores	score	NOUN
dpc-4976	48	13	.	.	PUNCT
dpc-4976	49	1	this	this	PRON
dpc-4976	49	2	included	include	VERB
dpc-4976	49	3	evaluating	evaluate	VERB
dpc-4976	49	4	the	the	DET
dpc-4976	49	5	mean	mean	ADJ
dpc-4976	49	6	pasi	pasi	NOUN
dpc-4976	49	7	scores	score	NOUN
dpc-4976	49	8	at	at	ADP
dpc-4976	49	9	different	different	ADJ
dpc-4976	49	10	timepoints	timepoint	NOUN
dpc-4976	49	11	(	(	PUNCT
dpc-4976	49	12	baseline	baseline	NOUN
dpc-4976	49	13	,	,	PUNCT
dpc-4976	49	14	week	week	NOUN
dpc-4976	49	15	4	4	NUM
dpc-4976	49	16	,	,	PUNCT
dpc-4976	49	17	week	week	NOUN
dpc-4976	49	18	16	16	NUM
dpc-4976	49	19	,	,	PUNCT
dpc-4976	49	20	week	week	NOUN
dpc-4976	49	21	24	24	NUM
dpc-4976	49	22	,	,	PUNCT
dpc-4976	49	23	and	and	CCONJ
dpc-4976	49	24	week	week	NOUN
dpc-4976	49	25	 	 	SPACE
dpc-4976	49	26	52	52	NUM
dpc-4976	49	27	)	)	PUNCT
dpc-4976	49	28	and	and	CCONJ
dpc-4976	49	29	according	accord	VERB
dpc-4976	49	30	to	to	ADP
dpc-4976	49	31	different	different	ADJ
dpc-4976	49	32	body	body	NOUN
dpc-4976	49	33	areas	area	NOUN
dpc-4976	49	34	(	(	PUNCT
dpc-4976	49	35	pasi	pasi	VERB
dpc-4976	49	36	subscore	subscore	NOUN
dpc-4976	49	37	:	:	PUNCT
dpc-4976	49	38	head	head	NOUN
dpc-4976	49	39	,	,	PUNCT
dpc-4976	49	40	lower	low	ADJ
dpc-4976	49	41	limb	limb	NOUN
dpc-4976	49	42	,	,	PUNCT
dpc-4976	49	43	upper	upper	ADJ
dpc-4976	49	44	limb	limb	NOUN
dpc-4976	49	45	,	,	PUNCT
dpc-4976	49	46	trunk	trunk	NOUN
dpc-4976	49	47	)	)	PUNCT
dpc-4976	49	48	and	and	CCONJ
dpc-4976	49	49	the	the	DET
dpc-4976	49	50	percentage	percentage	NOUN
dpc-4976	49	51	of	of	ADP
dpc-4976	49	52	patients	patient	NOUN
dpc-4976	49	53	achieving	achieve	VERB
dpc-4976	49	54	significant	significant	ADJ
dpc-4976	49	55	reductions	reduction	NOUN
dpc-4976	49	56	in	in	ADP
dpc-4976	49	57	pasi	pasi	NOUN
dpc-4976	49	58	scores	score	NOUN
dpc-4976	49	59	(	(	PUNCT
dpc-4976	49	60	e.g.	e.g.	ADV
dpc-4976	49	61	,	,	PUNCT
dpc-4976	49	62	pasi	pasi	NOUN
dpc-4976	49	63	90	90	NUM
dpc-4976	49	64	and	and	CCONJ
dpc-4976	49	65	pasi	pasi	NOUN
dpc-4976	49	66	100	100	NUM
dpc-4976	49	67	)	)	PUNCT
dpc-4976	49	68	.	.	PUNCT
dpc-4976	50	1	secondary	secondary	ADJ
dpc-4976	50	2	endpoints	endpoint	NOUN
dpc-4976	50	3	aimed	aim	VERB
dpc-4976	50	4	to	to	PART
dpc-4976	50	5	evaluate	evaluate	VERB
dpc-4976	50	6	the	the	DET
dpc-4976	50	7	impact	impact	NOUN
dpc-4976	50	8	of	of	ADP
dpc-4976	50	9	bimekizumab	bimekizumab	NOUN
dpc-4976	50	10	on	on	ADP
dpc-4976	50	11	the	the	DET
dpc-4976	50	12	patients	patient	NOUN
dpc-4976	50	13	’	'	PUNCT
dpc-4976	50	14	quality	quality	NOUN
dpc-4976	50	15	of	of	ADP
dpc-4976	50	16	life	life	NOUN
dpc-4976	50	17	using	use	VERB
dpc-4976	50	18	the	the	DET
dpc-4976	50	19	dermatology	dermatology	NOUN
dpc-4976	50	20	life	life	NOUN
dpc-4976	50	21	quality	quality	NOUN
dpc-4976	50	22	index	index	NOUN
dpc-4976	50	23	(	(	PUNCT
dpc-4976	50	24	dlqi	dlqi	PROPN
dpc-4976	50	25	)	)	PUNCT
dpc-4976	50	26	and	and	CCONJ
dpc-4976	50	27	the	the	DET
dpc-4976	50	28	drug	drug	NOUN
dpc-4976	50	29	’s	’s	PART
dpc-4976	50	30	effectiveness	effectiveness	NOUN
dpc-4976	50	31	in	in	ADP
dpc-4976	50	32	bio	bio	ADJ
dpc-4976	50	33	-	-	ADJ
dpc-4976	50	34	naive	naive	ADJ
dpc-4976	50	35	vs	vs	ADP
dpc-4976	50	36	bio	bio	ADJ
dpc-4976	50	37	-	-	ADJ
dpc-4976	50	38	experienced	experienced	ADJ
dpc-4976	50	39	patients	patient	NOUN
dpc-4976	50	40	.	.	PUNCT
dpc-4976	51	1	statistical	statistical	ADJ
dpc-4976	51	2	analysis	analysis	NOUN
dpc-4976	51	3	continuous	continuous	ADJ
dpc-4976	51	4	variables	variable	NOUN
dpc-4976	51	5	are	be	AUX
dpc-4976	51	6	described	describe	VERB
dpc-4976	51	7	using	use	VERB
dpc-4976	51	8	mean	mean	NOUN
dpc-4976	51	9	,	,	PUNCT
dpc-4976	51	10	median	median	ADJ
dpc-4976	51	11	and	and	CCONJ
dpc-4976	51	12	standard	standard	ADJ
dpc-4976	51	13	deviation	deviation	NOUN
dpc-4976	51	14	,	,	PUNCT
dpc-4976	51	15	while	while	SCONJ
dpc-4976	51	16	absolute	absolute	ADJ
dpc-4976	51	17	and	and	CCONJ
dpc-4976	51	18	relative	relative	ADJ
dpc-4976	51	19	frequencies	frequency	NOUN
dpc-4976	51	20	are	be	AUX
dpc-4976	51	21	provided	provide	VERB
dpc-4976	51	22	for	for	ADP
dpc-4976	51	23	discrete	discrete	ADJ
dpc-4976	51	24	variables	variable	NOUN
dpc-4976	51	25	.	.	PUNCT
dpc-4976	52	1	a	a	DET
dpc-4976	52	2	venn	venn	PROPN
dpc-4976	52	3	diagram	diagram	PROPN
dpc-4976	52	4	shows	show	VERB
dpc-4976	52	5	the	the	DET
dpc-4976	52	6	logical	logical	ADJ
dpc-4976	52	7	relation	relation	NOUN
dpc-4976	52	8	between	between	ADP
dpc-4976	52	9	locations	location	NOUN
dpc-4976	52	10	involved	involve	VERB
dpc-4976	52	11	.	.	PUNCT
dpc-4976	53	1	paired	pair	VERB
dpc-4976	53	2	t	t	PROPN
dpc-4976	53	3	-	-	PUNCT
dpc-4976	53	4	test	test	NOUN
dpc-4976	53	5	was	be	AUX
dpc-4976	53	6	used	use	VERB
dpc-4976	53	7	to	to	PART
dpc-4976	53	8	compare	compare	VERB
dpc-4976	53	9	changes	change	NOUN
dpc-4976	53	10	in	in	ADP
dpc-4976	53	11	pasi	pasi	NOUN
dpc-4976	53	12	subscores	subscore	NOUN
dpc-4976	53	13	at	at	ADP
dpc-4976	53	14	each	each	DET
dpc-4976	53	15	timepoint	timepoint	NOUN
dpc-4976	53	16	vs	vs	ADP
dpc-4976	53	17	baseline	baseline	NOUN
dpc-4976	53	18	.	.	PUNCT
dpc-4976	54	1	all	all	DET
dpc-4976	54	2	p	p	NOUN
dpc-4976	54	3	-	-	PUNCT
dpc-4976	54	4	values	value	NOUN
dpc-4976	54	5	were	be	AUX
dpc-4976	54	6	considered	consider	VERB
dpc-4976	54	7	nominal	nominal	ADJ
dpc-4976	54	8	,	,	PUNCT
dpc-4976	54	9	and	and	CCONJ
dpc-4976	54	10	a	a	DET
dpc-4976	54	11	value	value	NOUN
dpc-4976	54	12	<	<	NOUN
dpc-4976	54	13	0.05	0.05	NUM
dpc-4976	54	14	was	be	AUX
dpc-4976	54	15	considered	consider	VERB
dpc-4976	54	16	statistically	statistically	ADV
dpc-4976	54	17	significant	significant	ADJ
dpc-4976	54	18	.	.	PUNCT
dpc-4976	55	1	a	a	DET
dpc-4976	55	2	multivariate	multivariate	NOUN
dpc-4976	55	3	logistic	logistic	ADJ
dpc-4976	55	4	regression	regression	NOUN
dpc-4976	55	5	model	model	NOUN
dpc-4976	55	6	was	be	AUX
dpc-4976	55	7	used	use	VERB
dpc-4976	55	8	to	to	PART
dpc-4976	55	9	evaluate	evaluate	VERB
dpc-4976	55	10	determinant	determinant	ADJ
dpc-4976	55	11	factors	factor	NOUN
dpc-4976	55	12	to	to	PART
dpc-4976	55	13	pasi	pasi	VERB
dpc-4976	55	14	subscores	subscore	NOUN
dpc-4976	55	15	equal	equal	ADJ
dpc-4976	55	16	to	to	ADP
dpc-4976	55	17	0	0	NUM
dpc-4976	55	18	at	at	ADP
dpc-4976	55	19	week	week	NOUN
dpc-4976	55	20	16	16	NUM
dpc-4976	55	21	,	,	PUNCT
dpc-4976	55	22	considering	consider	VERB
dpc-4976	55	23	as	as	ADP
dpc-4976	55	24	factors	factor	NOUN
dpc-4976	55	25	bio	bio	NOUN
dpc-4976	55	26	-	-	NOUN
dpc-4976	55	27	treatment	treatment	NOUN
dpc-4976	55	28	(	(	PUNCT
dpc-4976	55	29	bio	bio	NOUN
dpc-4976	55	30	-	-	ADJ
dpc-4976	55	31	naive	naive	ADJ
dpc-4976	55	32	vs	vs	ADP
dpc-4976	55	33	bio	bio	NOUN
dpc-4976	55	34	-	-	ADJ
dpc-4976	55	35	experienced	experienced	ADJ
dpc-4976	55	36	)	)	PUNCT
dpc-4976	55	37	,	,	PUNCT
dpc-4976	55	38	sex	sex	NOUN
dpc-4976	55	39	,	,	PUNCT
dpc-4976	55	40	age	age	NOUN
dpc-4976	55	41	at	at	ADP
dpc-4976	55	42	first	first	ADJ
dpc-4976	55	43	bimekizumab	bimekizumab	X
dpc-4976	55	44	treatment	treatment	NOUN
dpc-4976	55	45	,	,	PUNCT
dpc-4976	55	46	time	time	NOUN
dpc-4976	55	47	from	from	ADP
dpc-4976	55	48	pso	pso	NOUN
dpc-4976	55	49	diagnosis	diagnosis	NOUN
dpc-4976	55	50	to	to	ADP
dpc-4976	55	51	bimekizumab	bimekizumab	NOUN
dpc-4976	55	52	initiation	initiation	NOUN
dpc-4976	55	53	,	,	PUNCT
dpc-4976	55	54	and	and	CCONJ
dpc-4976	55	55	bm/	bm/	NOUN
dpc-4976	55	56	(	(	PUNCT
dpc-4976	55	57	<	<	X
dpc-4976	55	58	25	25	NUM
dpc-4976	55	59	vs	vs	ADP
dpc-4976	55	60	>	>	PUNCT
dpc-4976	55	61	=	=	NOUN
dpc-4976	55	62	25	25	NUM
dpc-4976	55	63	)	)	PUNCT
dpc-4976	55	64	.	.	PUNCT
dpc-4976	56	1	an	an	DET
dpc-4976	56	2	anova	anova	PROPN
dpc-4976	56	3	model	model	NOUN
dpc-4976	56	4	for	for	ADP
dpc-4976	56	5	repeated	repeat	VERB
dpc-4976	56	6	measures	measure	NOUN
dpc-4976	56	7	and	and	CCONJ
dpc-4976	56	8	an	an	DET
dpc-4976	56	9	ancova	ancova	NOUN
dpc-4976	56	10	model	model	NOUN
dpc-4976	56	11	were	be	AUX
dpc-4976	56	12	used	use	VERB
dpc-4976	56	13	to	to	PART
dpc-4976	56	14	evaluate	evaluate	VERB
dpc-4976	56	15	the	the	DET
dpc-4976	56	16	pasi	pasi	NOUN
dpc-4976	56	17	reduction	reduction	NOUN
dpc-4976	56	18	in	in	ADP
dpc-4976	56	19	bio	bio	ADJ
dpc-4976	56	20	-	-	ADJ
dpc-4976	56	21	naive	naive	ADJ
dpc-4976	56	22	and	and	CCONJ
dpc-4976	56	23	bio	bio	ADJ
dpc-4976	56	24	-	-	ADJ
dpc-4976	56	25	experienced	experienced	ADJ
dpc-4976	56	26	patients	patient	NOUN
dpc-4976	56	27	.	.	PUNCT
dpc-4976	57	1	results	result	VERB
dpc-4976	57	2	patients	patient	NOUN
dpc-4976	57	3	baseline	baseline	VERB
dpc-4976	57	4	characteristics	characteristic	NOUN
dpc-4976	57	5	the	the	DET
dpc-4976	57	6	study	study	NOUN
dpc-4976	57	7	included	include	VERB
dpc-4976	57	8	132	132	NUM
dpc-4976	57	9	patients	patient	NOUN
dpc-4976	57	10	with	with	ADP
dpc-4976	57	11	a	a	DET
dpc-4976	57	12	mean	mean	ADJ
dpc-4976	57	13	age	age	NOUN
dpc-4976	57	14	of	of	ADP
dpc-4976	57	15	49.73	49.73	NUM
dpc-4976	57	16	years	year	NOUN
dpc-4976	57	17	(	(	PUNCT
dpc-4976	57	18	sd	sd	ADP
dpc-4976	57	19	14.63	14.63	NUM
dpc-4976	57	20	)	)	PUNCT
dpc-4976	57	21	.	.	PUNCT
dpc-4976	58	1	the	the	DET
dpc-4976	58	2	demographic	demographic	ADJ
dpc-4976	58	3	and	and	CCONJ
dpc-4976	58	4	clinical	clinical	ADJ
dpc-4976	58	5	characteristics	characteristic	NOUN
dpc-4976	58	6	of	of	ADP
dpc-4976	58	7	the	the	DET
dpc-4976	58	8	study	study	NOUN
dpc-4976	58	9	participants	participant	NOUN
dpc-4976	58	10	are	be	AUX
dpc-4976	58	11	summarized	summarize	VERB
dpc-4976	58	12	in	in	ADP
dpc-4976	58	13	table	table	NOUN
dpc-4976	58	14	2	2	NUM
dpc-4976	58	15	.	.	PUNCT
dpc-4976	58	16	pso	pso	NOUN
dpc-4976	58	17	involvement	involvement	NOUN
dpc-4976	58	18	psoriasis	psoriasis	NOUN
dpc-4976	58	19	involvement	involvement	NOUN
dpc-4976	58	20	was	be	AUX
dpc-4976	58	21	recorded	record	VERB
dpc-4976	58	22	in	in	ADP
dpc-4976	58	23	110	110	NUM
dpc-4976	58	24	patients	patient	NOUN
dpc-4976	58	25	for	for	ADP
dpc-4976	58	26	the	the	DET
dpc-4976	58	27	head	head	NOUN
dpc-4976	58	28	and	and	CCONJ
dpc-4976	58	29	neck	neck	NOUN
dpc-4976	58	30	,	,	PUNCT
dpc-4976	58	31	and	and	CCONJ
dpc-4976	58	32	in	in	ADP
dpc-4976	58	33	132	132	NUM
dpc-4976	58	34	patients	patient	NOUN
dpc-4976	58	35	for	for	ADP
dpc-4976	58	36	the	the	DET
dpc-4976	58	37	upper	upper	ADJ
dpc-4976	58	38	limbs	limb	NOUN
dpc-4976	58	39	,	,	PUNCT
dpc-4976	58	40	trunk	trunk	NOUN
dpc-4976	58	41	,	,	PUNCT
dpc-4976	58	42	and	and	CCONJ
dpc-4976	58	43	lower	low	ADJ
dpc-4976	58	44	limbs	limb	NOUN
dpc-4976	58	45	(	(	PUNCT
dpc-4976	58	46	figure	figure	NOUN
dpc-4976	58	47	s1	s1	PROPN
dpc-4976	58	48	a	a	PROPN
dpc-4976	58	49	-	-	PUNCT
dpc-4976	58	50	b	b	NOUN
dpc-4976	58	51	)	)	PUNCT
dpc-4976	58	52	.	.	PUNCT
dpc-4976	59	1	the	the	DET
dpc-4976	59	2	distribution	distribution	NOUN
dpc-4976	59	3	of	of	ADP
dpc-4976	59	4	affected	affected	ADJ
dpc-4976	59	5	areas	area	NOUN
dpc-4976	59	6	showed	show	VERB
dpc-4976	59	7	seven	seven	NUM
dpc-4976	59	8	patients	patient	NOUN
dpc-4976	59	9	with	with	ADP
dpc-4976	59	10	involvement	involvement	NOUN
dpc-4976	59	11	in	in	ADP
dpc-4976	59	12	one	one	NUM
dpc-4976	59	13	area	area	NOUN
dpc-4976	59	14	,	,	PUNCT
dpc-4976	59	15	17	17	NUM
dpc-4976	59	16	in	in	ADP
dpc-4976	59	17	two	two	NUM
dpc-4976	59	18	areas	area	NOUN
dpc-4976	59	19	,	,	PUNCT
dpc-4976	59	20	49	49	NUM
dpc-4976	59	21	in	in	ADP
dpc-4976	59	22	three	three	NUM
dpc-4976	59	23	areas	area	NOUN
dpc-4976	59	24	,	,	PUNCT
dpc-4976	59	25	and	and	CCONJ
dpc-4976	59	26	38	38	NUM
dpc-4976	59	27	in	in	ADP
dpc-4976	59	28	all	all	DET
dpc-4976	59	29	four	four	NUM
dpc-4976	59	30	areas	area	NOUN
dpc-4976	59	31	(	(	PUNCT
dpc-4976	59	32	figure	figure	NOUN
dpc-4976	59	33	s1	s1	PROPN
dpc-4976	59	34	c	c	NOUN
dpc-4976	59	35	)	)	PUNCT
dpc-4976	59	36	.	.	PUNCT
dpc-4976	60	1	among	among	ADP
dpc-4976	60	2	102	102	NUM
dpc-4976	60	3	patients	patient	NOUN
dpc-4976	60	4	analyzed	analyze	VERB
dpc-4976	60	5	for	for	ADP
dpc-4976	60	6	palmoplantar	palmoplantar	NOUN
dpc-4976	60	7	involvement	involvement	NOUN
dpc-4976	60	8	,	,	PUNCT
dpc-4976	60	9	nine	nine	NUM
dpc-4976	60	10	were	be	AUX
dpc-4976	60	11	involved	involve	VERB
dpc-4976	60	12	,	,	PUNCT
dpc-4976	60	13	while	while	SCONJ
dpc-4976	60	14	93	93	NUM
dpc-4976	60	15	did	do	AUX
dpc-4976	60	16	not	not	PART
dpc-4976	60	17	(	(	PUNCT
dpc-4976	60	18	figure	figure	VERB
dpc-4976	60	19	s1	s1	PROPN
dpc-4976	60	20	d	d	PROPN
dpc-4976	60	21	)	)	PUNCT
dpc-4976	60	22	.	.	PUNCT
dpc-4976	61	1	biologic	biologic	NOUN
dpc-4976	61	2	therapy	therapy	NOUN
dpc-4976	61	3	before	before	ADP
dpc-4976	61	4	bimekizumab	bimekizumab	NOUN
dpc-4976	61	5	among	among	ADP
dpc-4976	61	6	the	the	DET
dpc-4976	61	7	132	132	NUM
dpc-4976	61	8	enrolled	enrol	VERB
dpc-4976	61	9	patients	patient	NOUN
dpc-4976	61	10	,	,	PUNCT
dpc-4976	61	11	66	66	NUM
dpc-4976	61	12	were	be	AUX
dpc-4976	61	13	biologic	biologic	NOUN
dpc-4976	61	14	experienced	experience	VERB
dpc-4976	61	15	,	,	PUNCT
dpc-4976	61	16	and	and	CCONJ
dpc-4976	61	17	66	66	NUM
dpc-4976	61	18	were	be	AUX
dpc-4976	61	19	biologic	biologic	NOUN
dpc-4976	61	20	-	-	PUNCT
dpc-4976	61	21	naive	naive	ADJ
dpc-4976	61	22	.	.	PUNCT
dpc-4976	62	1	furthermore	furthermore	ADV
dpc-4976	62	2	,	,	PUNCT
dpc-4976	62	3	the	the	DET
dpc-4976	62	4	number	number	NOUN
dpc-4976	62	5	of	of	ADP
dpc-4976	62	6	biologic	biologic	NOUN
dpc-4976	62	7	treatments	treatment	NOUN
dpc-4976	62	8	received	receive	VERB
dpc-4976	62	9	before	before	ADP
dpc-4976	62	10	starting	start	VERB
dpc-4976	62	11	bimekizumab	bimekizumab	NOUN
dpc-4976	62	12	shows	show	VERB
dpc-4976	62	13	that	that	SCONJ
dpc-4976	62	14	among	among	ADP
dpc-4976	62	15	all	all	DET
dpc-4976	62	16	enrolled	enrol	VERB
dpc-4976	62	17	patients	patient	NOUN
dpc-4976	62	18	,	,	PUNCT
dpc-4976	62	19	85	85	NUM
dpc-4976	62	20	%	%	NOUN
dpc-4976	62	21	had	have	AUX
dpc-4976	62	22	received	receive	VERB
dpc-4976	62	23	one	one	NUM
dpc-4976	62	24	prior	prior	ADJ
dpc-4976	62	25	biologic	biologic	NOUN
dpc-4976	62	26	therapy	therapy	NOUN
dpc-4976	62	27	,	,	PUNCT
dpc-4976	62	28	7	7	NUM
dpc-4976	62	29	%	%	NOUN
dpc-4976	62	30	had	have	AUX
dpc-4976	62	31	received	receive	VERB
dpc-4976	62	32	two	two	NUM
dpc-4976	62	33	,	,	PUNCT
dpc-4976	62	34	and	and	CCONJ
dpc-4976	62	35	8	8	NUM
dpc-4976	62	36	%	%	NOUN
dpc-4976	62	37	had	have	AUX
dpc-4976	62	38	received	receive	VERB
dpc-4976	62	39	more	more	ADJ
dpc-4976	62	40	than	than	ADP
dpc-4976	62	41	two	two	NUM
dpc-4976	62	42	(	(	PUNCT
dpc-4976	62	43	figure	figure	NOUN
dpc-4976	62	44	s2	s2	VERB
dpc-4976	62	45	a	a	DET
dpc-4976	62	46	-	-	PUNCT
dpc-4976	62	47	b	b	NOUN
dpc-4976	62	48	)	)	PUNCT
dpc-4976	62	49	.	.	PUNCT
dpc-4976	63	1	efficacy	efficacy	NOUN
dpc-4976	63	2	of	of	ADP
dpc-4976	63	3	bimekizumab	bimekizumab	NOUN
dpc-4976	63	4	over	over	ADP
dpc-4976	63	5	time	time	NOUN
dpc-4976	63	6	pasi	pasi	PROPN
dpc-4976	63	7	score	score	NOUN
dpc-4976	63	8	:	:	PUNCT
dpc-4976	63	9	for	for	ADP
dpc-4976	63	10	all	all	DET
dpc-4976	63	11	enrolled	enrol	VERB
dpc-4976	63	12	patients	patient	NOUN
dpc-4976	63	13	(	(	PUNCT
dpc-4976	63	14	n=132	n=132	PROPN
dpc-4976	63	15	)	)	PUNCT
dpc-4976	63	16	,	,	PUNCT
dpc-4976	63	17	the	the	DET
dpc-4976	63	18	mean	mean	ADJ
dpc-4976	63	19	pasi	pasi	NOUN
dpc-4976	63	20	score	score	NOUN
dpc-4976	63	21	decreased	decrease	VERB
dpc-4976	63	22	from	from	ADP
dpc-4976	63	23	14.41	14.41	NUM
dpc-4976	63	24	at	at	ADP
dpc-4976	63	25	baseline	baseline	NOUN
dpc-4976	63	26	to	to	ADP
dpc-4976	63	27	2.31	2.31	NUM
dpc-4976	63	28	at	at	ADP
dpc-4976	63	29	week	week	NOUN
dpc-4976	63	30	4	4	NUM
dpc-4976	63	31	(	(	PUNCT
dpc-4976	63	32	n=126	n=126	NUM
dpc-4976	63	33	)	)	PUNCT
dpc-4976	63	34	,	,	PUNCT
dpc-4976	63	35	0.41	0.41	NUM
dpc-4976	63	36	at	at	ADP
dpc-4976	63	37	week	week	NOUN
dpc-4976	63	38	16	16	NUM
dpc-4976	63	39	(	(	PUNCT
dpc-4976	63	40	n=116	n=116	NUM
dpc-4976	63	41	)	)	PUNCT
dpc-4976	63	42	,	,	PUNCT
dpc-4976	63	43	0.24	0.24	NUM
dpc-4976	63	44	at	at	ADP
dpc-4976	63	45	week	week	NOUN
dpc-4976	63	46	24	24	NUM
dpc-4976	63	47	(	(	PUNCT
dpc-4976	63	48	n=91	n=91	NOUN
dpc-4976	63	49	)	)	PUNCT
dpc-4976	63	50	,	,	PUNCT
dpc-4976	63	51	and	and	CCONJ
dpc-4976	63	52	0.18	0.18	NUM
dpc-4976	63	53	at	at	ADP
dpc-4976	63	54	week	week	NOUN
dpc-4976	63	55	52	52	NUM
dpc-4976	63	56	(	(	PUNCT
dpc-4976	63	57	n=39	n=39	NOUN
dpc-4976	63	58	)	)	PUNCT
dpc-4976	63	59	,	,	PUNCT
dpc-4976	63	60	indicating	indicate	VERB
dpc-4976	63	61	a	a	DET
dpc-4976	63	62	significant	significant	ADJ
dpc-4976	63	63	reduction	reduction	NOUN
dpc-4976	63	64	in	in	ADP
dpc-4976	63	65	psoriasis	psoriasis	NOUN
dpc-4976	63	66	severity	severity	NOUN
dpc-4976	63	67	over	over	ADP
dpc-4976	63	68	time	time	NOUN
dpc-4976	63	69	(	(	PUNCT
dpc-4976	63	70	figure	figure	NOUN
dpc-4976	63	71	1	1	NUM
dpc-4976	63	72	)	)	PUNCT
dpc-4976	63	73	.	.	PUNCT
dpc-4976	64	1	baseline	baseline	PROPN
dpc-4976	64	2	pasi	pasi	PROPN
dpc-4976	64	3	scores	score	NOUN
dpc-4976	64	4	by	by	ADP
dpc-4976	64	5	area	area	NOUN
dpc-4976	64	6	were	be	AUX
dpc-4976	64	7	:	:	PUNCT
dpc-4976	64	8	head	head	NOUN
dpc-4976	64	9	(	(	PUNCT
dpc-4976	64	10	3.24	3.24	NUM
dpc-4976	64	11	)	)	PUNCT
dpc-4976	64	12	,	,	PUNCT
dpc-4976	64	13	upper	upper	ADJ
dpc-4976	64	14	limb	limb	NOUN
dpc-4976	64	15	(	(	PUNCT
dpc-4976	64	16	8.49	8.49	NUM
dpc-4976	64	17	)	)	PUNCT
dpc-4976	64	18	,	,	PUNCT
dpc-4976	64	19	trunk	trunk	NOUN
dpc-4976	64	20	(	(	PUNCT
dpc-4976	64	21	8.35	8.35	NUM
dpc-4976	64	22	)	)	PUNCT
dpc-4976	64	23	,	,	PUNCT
dpc-4976	64	24	and	and	CCONJ
dpc-4976	64	25	lower	low	ADJ
dpc-4976	64	26	limb	limb	NOUN
dpc-4976	64	27	(	(	PUNCT
dpc-4976	64	28	8.61	8.61	NUM
dpc-4976	64	29	)	)	PUNCT
dpc-4976	64	30	.	.	PUNCT
dpc-4976	65	1	by	by	ADP
dpc-4976	65	2	week	week	NOUN
dpc-4976	65	3	24	24	NUM
dpc-4976	65	4	,	,	PUNCT
dpc-4976	65	5	these	these	DET
dpc-4976	65	6	scores	score	NOUN
dpc-4976	65	7	decreased	decrease	VERB
dpc-4976	65	8	to	to	ADP
dpc-4976	65	9	0.21	0.21	NUM
dpc-4976	65	10	,	,	PUNCT
dpc-4976	65	11	0.09	0.09	NUM
dpc-4976	65	12	,	,	PUNCT
dpc-4976	65	13	0.03	0.03	NUM
dpc-4976	65	14	,	,	PUNCT
dpc-4976	65	15	and	and	CCONJ
dpc-4976	65	16	0.03	0.03	NUM
dpc-4976	65	17	,	,	PUNCT
dpc-4976	65	18	respectively	respectively	ADV
dpc-4976	65	19	.	.	PUNCT
dpc-4976	66	1	by	by	ADP
dpc-4976	66	2	week	week	NOUN
dpc-4976	66	3	54	54	NUM
dpc-4976	66	4	,	,	PUNCT
dpc-4976	66	5	the	the	DET
dpc-4976	66	6	scores	score	NOUN
dpc-4976	66	7	further	far	ADV
dpc-4976	66	8	decreased	decrease	VERB
dpc-4976	66	9	to	to	ADP
dpc-4976	66	10	0.13	0.13	NUM
dpc-4976	66	11	(	(	PUNCT
dpc-4976	66	12	head	head	NOUN
dpc-4976	66	13	)	)	PUNCT
dpc-4976	66	14	,	,	PUNCT
dpc-4976	66	15	0	0	NUM
dpc-4976	67	1	(	(	PUNCT
dpc-4976	67	2	upper	upper	ADJ
dpc-4976	67	3	limb	limb	NOUN
dpc-4976	67	4	)	)	PUNCT
dpc-4976	67	5	,	,	PUNCT
dpc-4976	67	6	0.03	0.03	NUM
dpc-4976	67	7	(	(	PUNCT
dpc-4976	67	8	trunk	trunk	NOUN
dpc-4976	67	9	)	)	PUNCT
dpc-4976	67	10	,	,	PUNCT
dpc-4976	67	11	and	and	CCONJ
dpc-4976	67	12	0.12	0.12	NUM
dpc-4976	67	13	(	(	PUNCT
dpc-4976	67	14	lower	low	ADJ
dpc-4976	67	15	limb	limb	NOUN
dpc-4976	67	16	)	)	PUNCT
dpc-4976	67	17	(	(	PUNCT
dpc-4976	67	18	figure	figure	NOUN
dpc-4976	67	19	2	2	NUM
dpc-4976	67	20	)	)	PUNCT
dpc-4976	67	21	.	.	PUNCT
dpc-4976	68	1	by	by	ADP
dpc-4976	68	2	week	week	NOUN
dpc-4976	68	3	4	4	NUM
dpc-4976	68	4	,	,	PUNCT
dpc-4976	68	5	67	67	NUM
dpc-4976	68	6	%	%	NOUN
dpc-4976	68	7	of	of	ADP
dpc-4976	68	8	patients	patient	NOUN
dpc-4976	68	9	achieved	achieve	VERB
dpc-4976	68	10	pasi	pasi	NOUN
dpc-4976	68	11	0	0	NUM
dpc-4976	68	12	for	for	ADP
dpc-4976	68	13	the	the	DET
dpc-4976	68	14	head	head	NOUN
dpc-4976	68	15	,	,	PUNCT
dpc-4976	68	16	53	53	NUM
dpc-4976	68	17	%	%	NOUN
dpc-4976	68	18	for	for	ADP
dpc-4976	68	19	the	the	DET
dpc-4976	68	20	upper	upper	ADJ
dpc-4976	68	21	limbs	limb	NOUN
dpc-4976	68	22	,	,	PUNCT
dpc-4976	68	23	52	52	NUM
dpc-4976	68	24	%	%	NOUN
dpc-4976	68	25	for	for	ADP
dpc-4976	68	26	the	the	DET
dpc-4976	68	27	trunk	trunk	NOUN
dpc-4976	68	28	,	,	PUNCT
dpc-4976	68	29	and	and	CCONJ
dpc-4976	68	30	53	53	NUM
dpc-4976	68	31	%	%	NOUN
dpc-4976	68	32	for	for	ADP
dpc-4976	68	33	the	the	DET
dpc-4976	68	34	lower	low	ADJ
dpc-4976	68	35	limbs	limb	NOUN
dpc-4976	68	36	.	.	PUNCT
dpc-4976	69	1	these	these	PRON
dpc-4976	69	2	increased	increase	VERB
dpc-4976	69	3	to	to	ADP
dpc-4976	69	4	85	85	NUM
dpc-4976	69	5	-	-	SYM
dpc-4976	69	6	94	94	NUM
dpc-4976	69	7	%	%	NOUN
dpc-4976	69	8	across	across	ADP
dpc-4976	69	9	all	all	DET
dpc-4976	69	10	areas	area	NOUN
dpc-4976	69	11	by	by	ADP
dpc-4976	69	12	week	week	NOUN
dpc-4976	69	13	16	16	NUM
dpc-4976	69	14	and	and	CCONJ
dpc-4976	69	15	maintained	maintain	VERB
dpc-4976	69	16	similar	similar	ADJ
dpc-4976	69	17	levels	level	NOUN
dpc-4976	69	18	through	through	ADP
dpc-4976	69	19	week	week	NOUN
dpc-4976	69	20	54	54	NUM
dpc-4976	69	21	(	(	PUNCT
dpc-4976	69	22	figure	figure	NOUN
dpc-4976	69	23	3	3	NUM
dpc-4976	69	24	)	)	PUNCT
dpc-4976	69	25	.	.	PUNCT
dpc-4976	70	1	table	table	NOUN
dpc-4976	70	2	1	1	NUM
dpc-4976	70	3	.	.	PUNCT
dpc-4976	71	1	centers	center	NOUN
dpc-4976	71	2	involved	involve	VERB
dpc-4976	71	3	in	in	ADP
dpc-4976	71	4	the	the	DET
dpc-4976	71	5	study	study	NOUN
dpc-4976	71	6	.	.	PUNCT
dpc-4976	72	1	center	center	PROPN
dpc-4976	72	2	uoc	uoc	NOUN
dpc-4976	72	3	of	of	ADP
dpc-4976	72	4	dermatology	dermatology	NOUN
dpc-4976	72	5	,	,	PUNCT
dpc-4976	72	6	policlinico	policlinico	NOUN
dpc-4976	72	7	umberto	umberto	NOUN
dpc-4976	73	1	i	i	PROPN
dpc-4976	73	2	,	,	PUNCT
dpc-4976	73	3	sapienza	sapienza	PROPN
dpc-4976	73	4	university	university	PROPN
dpc-4976	73	5	of	of	ADP
dpc-4976	73	6	rome	rome	PROPN
dpc-4976	73	7	uoc	uoc	PROPN
dpc-4976	73	8	of	of	ADP
dpc-4976	73	9	dermatology	dermatology	NOUN
dpc-4976	73	10	polo	polo	NOUN
dpc-4976	73	11	pontino	pontino	NOUN
dpc-4976	73	12	,	,	PUNCT
dpc-4976	73	13	sapienza	sapienza	PROPN
dpc-4976	73	14	university	university	PROPN
dpc-4976	73	15	of	of	ADP
dpc-4976	73	16	rome	rome	PROPN
dpc-4976	73	17	uoc	uoc	PROPN
dpc-4976	73	18	of	of	ADP
dpc-4976	73	19	dermatology	dermatology	NOUN
dpc-4976	73	20	,	,	PUNCT
dpc-4976	73	21	a.o	a.o	PROPN
dpc-4976	73	22	.	.	PROPN
dpc-4976	73	23	sant’andrea	sant’andrea	PROPN
dpc-4976	73	24	,	,	PUNCT
dpc-4976	73	25	sapienza	sapienza	PROPN
dpc-4976	73	26	university	university	PROPN
dpc-4976	73	27	of	of	ADP
dpc-4976	73	28	rome	rome	PROPN
dpc-4976	73	29	uosd	uosd	ADV
dpc-4976	73	30	of	of	ADP
dpc-4976	73	31	dermatology	dermatology	NOUN
dpc-4976	73	32	,	,	PUNCT
dpc-4976	73	33	university	university	NOUN
dpc-4976	73	34	of	of	ADP
dpc-4976	73	35	rome	rome	PROPN
dpc-4976	73	36	tor	tor	PROPN
dpc-4976	73	37	vergata	vergata	PROPN
dpc-4976	73	38	uoc	uoc	PROPN
dpc-4976	73	39	of	of	ADP
dpc-4976	73	40	dermatology	dermatology	NOUN
dpc-4976	73	41	,	,	PUNCT
dpc-4976	73	42	policlinico	policlinico	NOUN
dpc-4976	73	43	agostino	agostino	PROPN
dpc-4976	73	44	gemelli	gemelli	PROPN
dpc-4976	73	45	dermopatic	dermopatic	PROPN
dpc-4976	73	46	institute	institute	PROPN
dpc-4976	73	47	of	of	ADP
dpc-4976	73	48	immaculate	immaculate	PROPN
dpc-4976	73	49	(	(	PUNCT
dpc-4976	73	50	idi	idi	NOUN
dpc-4976	73	51	)	)	PUNCT
dpc-4976	73	52	irccs	irccs	PROPN
dpc-4976	73	53	,	,	PUNCT
dpc-4976	73	54	rome	rome	PROPN
dpc-4976	73	55	ospedale	ospedale	PROPN
dpc-4976	73	56	viterbo	viterbo	PROPN
dpc-4976	73	57	uos	uos	PROPN
dpc-4976	73	58	of	of	ADP
dpc-4976	73	59	dermatology	dermatology	NOUN
dpc-4976	73	60	campus	campus	NOUN
dpc-4976	73	61	bio	bio	NOUN
dpc-4976	73	62	-	-	NOUN
dpc-4976	73	63	medico	medico	NOUN
dpc-4976	73	64	of	of	ADP
dpc-4976	73	65	rome	rome	PROPN
dpc-4976	73	66	table	table	NOUN
dpc-4976	73	67	2	2	NUM
dpc-4976	73	68	.	.	PUNCT
dpc-4976	74	1	patients	patient	NOUN
dpc-4976	74	2	’	'	PUNCT
dpc-4976	74	3	baseline	baseline	PROPN
dpc-4976	74	4	characteristics	characteristic	NOUN
dpc-4976	74	5	.	.	PUNCT
dpc-4976	75	1	patients	patient	NOUN
dpc-4976	75	2	age	age	NOUN
dpc-4976	75	3	(	(	PUNCT
dpc-4976	75	4	yrs	yr	NOUN
dpc-4976	75	5	)	)	PUNCT
dpc-4976	75	6	n	n	PRON
dpc-4976	75	7	132	132	NUM
dpc-4976	75	8	mean	mean	NOUN
dpc-4976	75	9	(	(	PUNCT
dpc-4976	75	10	sd	sd	NOUN
dpc-4976	75	11	)	)	PUNCT
dpc-4976	75	12	49.73	49.73	NUM
dpc-4976	75	13	(	(	PUNCT
dpc-4976	75	14	14.63	14.63	NUM
dpc-4976	75	15	)	)	PUNCT
dpc-4976	75	16	weight	weight	NOUN
dpc-4976	75	17	(	(	PUNCT
dpc-4976	75	18	kg	kg	NOUN
dpc-4976	75	19	)	)	PUNCT
dpc-4976	75	20	n	n	PRON
dpc-4976	75	21	123	123	NUM
dpc-4976	75	22	mean	mean	NOUN
dpc-4976	75	23	(	(	PUNCT
dpc-4976	75	24	sd	sd	NOUN
dpc-4976	75	25	)	)	PUNCT
dpc-4976	75	26	74.02	74.02	NUM
dpc-4976	75	27	(	(	PUNCT
dpc-4976	75	28	15.63	15.63	NUM
dpc-4976	75	29	)	)	PUNCT
dpc-4976	75	30	bmi	bmi	NOUN
dpc-4976	75	31	n	n	PRON
dpc-4976	75	32	120	120	NUM
dpc-4976	75	33	mean	mean	NOUN
dpc-4976	75	34	(	(	PUNCT
dpc-4976	75	35	sd	sd	NOUN
dpc-4976	75	36	)	)	PUNCT
dpc-4976	75	37	25.57	25.57	NUM
dpc-4976	75	38	(	(	PUNCT
dpc-4976	75	39	4.43	4.43	NUM
dpc-4976	75	40	)	)	PUNCT
dpc-4976	75	41	age	age	NOUN
dpc-4976	75	42	at	at	ADP
dpc-4976	75	43	pso	pso	NOUN
dpc-4976	75	44	diagnosis	diagnosis	NOUN
dpc-4976	75	45	(	(	PUNCT
dpc-4976	75	46	yrs	yr	NOUN
dpc-4976	75	47	)	)	PUNCT
dpc-4976	75	48	n	n	PRON
dpc-4976	75	49	129	129	NUM
dpc-4976	75	50	mean	mean	NOUN
dpc-4976	75	51	(	(	PUNCT
dpc-4976	75	52	sd	sd	NOUN
dpc-4976	75	53	)	)	PUNCT
dpc-4976	75	54	29.16	29.16	NUM
dpc-4976	75	55	(	(	PUNCT
dpc-4976	75	56	17.90	17.90	NUM
dpc-4976	75	57	)	)	PUNCT
dpc-4976	75	58	time	time	NOUN
dpc-4976	75	59	from	from	ADP
dpc-4976	75	60	pso	pso	NOUN
dpc-4976	75	61	diagnosis	diagnosis	NOUN
dpc-4976	75	62	to	to	PART
dpc-4976	75	63	bkz	bkz	PROPN
dpc-4976	75	64	(	(	PUNCT
dpc-4976	75	65	yrs	yr	NOUN
dpc-4976	75	66	)	)	PUNCT
dpc-4976	75	67	n	n	PRON
dpc-4976	76	1	124	124	NUM
dpc-4976	76	2	mean	mean	NOUN
dpc-4976	76	3	(	(	PUNCT
dpc-4976	76	4	sd	sd	NOUN
dpc-4976	76	5	)	)	PUNCT
dpc-4976	76	6	21.78	21.78	NUM
dpc-4976	76	7	(	(	PUNCT
dpc-4976	76	8	16.53	16.53	NUM
dpc-4976	76	9	)	)	PUNCT
dpc-4976	76	10	abbreviations	abbreviation	NOUN
dpc-4976	76	11	:	:	PUNCT
dpc-4976	76	12	bkz	bkz	ADV
dpc-4976	76	13	:	:	PUNCT
dpc-4976	76	14	bimekizumab	bimekizumab	ADV
dpc-4976	76	15	;	;	PUNCT
dpc-4976	76	16	bmi	bmi	PROPN
dpc-4976	76	17	:	:	PUNCT
dpc-4976	76	18	body	body	NOUN
dpc-4976	76	19	mass	mass	PROPN
dpc-4976	76	20	index	index	NOUN
dpc-4976	76	21	;	;	PUNCT
dpc-4976	76	22	pso	pso	NOUN
dpc-4976	76	23	:	:	PUNCT
dpc-4976	76	24	psoriasis	psoriasis	NOUN
dpc-4976	76	25	;	;	PUNCT
dpc-4976	76	26	sd	sd	X
dpc-4976	76	27	:	:	PUNCT
dpc-4976	76	28	standard	standard	ADJ
dpc-4976	76	29	deviation	deviation	NOUN
dpc-4976	76	30	.	.	PUNCT
dpc-4976	77	1	4	4	NUM
dpc-4976	77	2	original	original	ADJ
dpc-4976	77	3	article	article	NOUN
dpc-4976	77	4	|	|	ADV
dpc-4976	77	5	dermatol	dermatol	ADJ
dpc-4976	77	6	pract	pract	NOUN
dpc-4976	77	7	concept	concept	NOUN
dpc-4976	77	8	.	.	PUNCT
dpc-4976	78	1	2025;15(1):4976	2025;15(1):4976	NUM
dpc-4976	78	2	figure	figure	NOUN
dpc-4976	78	3	1	1	NUM
dpc-4976	78	4	.	.	PUNCT
dpc-4976	79	1	mean	mean	PROPN
dpc-4976	79	2	pasi	pasi	NOUN
dpc-4976	79	3	score	score	NOUN
dpc-4976	79	4	over	over	ADP
dpc-4976	79	5	time	time	NOUN
dpc-4976	79	6	for	for	ADP
dpc-4976	79	7	all	all	DET
dpc-4976	79	8	enrolled	enrol	VERB
dpc-4976	79	9	patients	patient	NOUN
dpc-4976	79	10	.	.	PUNCT
dpc-4976	80	1	(	(	PUNCT
dpc-4976	80	2	n=132	n=132	PROPN
dpc-4976	80	3	)	)	PUNCT
dpc-4976	80	4	.	.	PUNCT
dpc-4976	81	1	the	the	DET
dpc-4976	81	2	mean	mean	ADJ
dpc-4976	81	3	pasi	pasi	NOUN
dpc-4976	81	4	scores	score	NOUN
dpc-4976	81	5	are	be	AUX
dpc-4976	81	6	presented	present	VERB
dpc-4976	81	7	at	at	ADP
dpc-4976	81	8	baseline	baseline	NOUN
dpc-4976	81	9	,	,	PUNCT
dpc-4976	81	10	week	week	NOUN
dpc-4976	81	11	4	4	NUM
dpc-4976	81	12	(	(	PUNCT
dpc-4976	81	13	n=126	n=126	NUM
dpc-4976	81	14	)	)	PUNCT
dpc-4976	81	15	,	,	PUNCT
dpc-4976	81	16	week	week	NOUN
dpc-4976	81	17	16	16	NUM
dpc-4976	81	18	(	(	PUNCT
dpc-4976	81	19	n=116	n=116	NUM
dpc-4976	81	20	)	)	PUNCT
dpc-4976	81	21	,	,	PUNCT
dpc-4976	81	22	week	week	NOUN
dpc-4976	81	23	24	24	NUM
dpc-4976	81	24	(	(	PUNCT
dpc-4976	81	25	n=91	n=91	NOUN
dpc-4976	81	26	)	)	PUNCT
dpc-4976	81	27	,	,	PUNCT
dpc-4976	81	28	and	and	CCONJ
dpc-4976	81	29	week	week	NOUN
dpc-4976	81	30	52	52	NUM
dpc-4976	81	31	(	(	PUNCT
dpc-4976	81	32	n=39	n=39	NOUN
dpc-4976	81	33	)	)	PUNCT
dpc-4976	81	34	.	.	PUNCT
dpc-4976	82	1	the	the	DET
dpc-4976	82	2	scores	score	NOUN
dpc-4976	82	3	show	show	VERB
dpc-4976	82	4	a	a	DET
dpc-4976	82	5	significant	significant	ADJ
dpc-4976	82	6	reduction	reduction	NOUN
dpc-4976	82	7	from	from	ADP
dpc-4976	82	8	a	a	DET
dpc-4976	82	9	mean	mean	ADJ
dpc-4976	82	10	value	value	NOUN
dpc-4976	82	11	of	of	ADP
dpc-4976	82	12	14.41	14.41	NUM
dpc-4976	82	13	at	at	ADP
dpc-4976	82	14	baseline	baseline	NOUN
dpc-4976	82	15	to	to	ADP
dpc-4976	82	16	0.18	0.18	NUM
dpc-4976	82	17	at	at	ADP
dpc-4976	82	18	week	week	NOUN
dpc-4976	82	19	52	52	NUM
dpc-4976	82	20	,	,	PUNCT
dpc-4976	82	21	indicating	indicate	VERB
dpc-4976	82	22	a	a	DET
dpc-4976	82	23	substantial	substantial	ADJ
dpc-4976	82	24	improvement	improvement	NOUN
dpc-4976	82	25	in	in	ADP
dpc-4976	82	26	psoriasis	psoriasis	NOUN
dpc-4976	82	27	severity	severity	NOUN
dpc-4976	82	28	.	.	PUNCT
dpc-4976	83	1	figure	figure	NOUN
dpc-4976	83	2	2	2	NUM
dpc-4976	83	3	.	.	PUNCT
dpc-4976	83	4	pasi	pasi	NOUN
dpc-4976	83	5	subscores	subscore	NOUN
dpc-4976	83	6	by	by	ADP
dpc-4976	83	7	body	body	NOUN
dpc-4976	83	8	area	area	NOUN
dpc-4976	83	9	over	over	ADP
dpc-4976	83	10	time	time	NOUN
dpc-4976	83	11	.	.	PUNCT
dpc-4976	84	1	mean	mean	VERB
dpc-4976	84	2	pasi	pasi	NOUN
dpc-4976	84	3	subscores	subscore	NOUN
dpc-4976	84	4	by	by	ADP
dpc-4976	84	5	body	body	NOUN
dpc-4976	84	6	area	area	NOUN
dpc-4976	84	7	(	(	PUNCT
dpc-4976	84	8	head	head	NOUN
dpc-4976	84	9	,	,	PUNCT
dpc-4976	84	10	upper	upper	ADJ
dpc-4976	84	11	limb	limb	NOUN
dpc-4976	84	12	,	,	PUNCT
dpc-4976	84	13	trunk	trunk	NOUN
dpc-4976	84	14	,	,	PUNCT
dpc-4976	84	15	lower	low	ADJ
dpc-4976	84	16	limb	limb	NOUN
dpc-4976	84	17	)	)	PUNCT
dpc-4976	84	18	over	over	ADP
dpc-4976	84	19	time	time	NOUN
dpc-4976	84	20	for	for	ADP
dpc-4976	84	21	all	all	DET
dpc-4976	84	22	enrolled	enrol	VERB
dpc-4976	84	23	patients	patient	NOUN
dpc-4976	84	24	.	.	PUNCT
dpc-4976	85	1	the	the	DET
dpc-4976	85	2	pasi	pasi	NOUN
dpc-4976	85	3	subscores	subscore	NOUN
dpc-4976	85	4	were	be	AUX
dpc-4976	85	5	recorded	record	VERB
dpc-4976	85	6	at	at	ADP
dpc-4976	85	7	baseline	baseline	NOUN
dpc-4976	85	8	,	,	PUNCT
dpc-4976	85	9	week	week	NOUN
dpc-4976	85	10	4	4	NUM
dpc-4976	85	11	(	(	PUNCT
dpc-4976	85	12	w4	w4	NOUN
dpc-4976	85	13	)	)	PUNCT
dpc-4976	85	14	,	,	PUNCT
dpc-4976	85	15	week	week	NOUN
dpc-4976	85	16	16	16	NUM
dpc-4976	85	17	(	(	PUNCT
dpc-4976	85	18	w16	w16	NOUN
dpc-4976	85	19	)	)	PUNCT
dpc-4976	85	20	,	,	PUNCT
dpc-4976	85	21	week	week	NOUN
dpc-4976	85	22	24	24	NUM
dpc-4976	85	23	(	(	PUNCT
dpc-4976	85	24	w24	w24	PROPN
dpc-4976	85	25	)	)	PUNCT
dpc-4976	85	26	,	,	PUNCT
dpc-4976	85	27	and	and	CCONJ
dpc-4976	85	28	week	week	NOUN
dpc-4976	85	29	52	52	NUM
dpc-4976	85	30	(	(	PUNCT
dpc-4976	85	31	w52	w52	NOUN
dpc-4976	85	32	)	)	PUNCT
dpc-4976	85	33	.	.	PUNCT
dpc-4976	86	1	pasi	pasi	PROPN
dpc-4976	86	2	score	score	PROPN
dpc-4976	86	3	based	base	VERB
dpc-4976	86	4	on	on	ADP
dpc-4976	86	5	previous	previous	ADJ
dpc-4976	86	6	therapy	therapy	NOUN
dpc-4976	86	7	:	:	PUNCT
dpc-4976	86	8	the	the	DET
dpc-4976	86	9	pasi	pasi	NOUN
dpc-4976	86	10	score	score	NOUN
dpc-4976	86	11	trend	trend	NOUN
dpc-4976	86	12	between	between	ADP
dpc-4976	86	13	bio	bio	NOUN
dpc-4976	86	14	-	-	ADJ
dpc-4976	86	15	naive	naive	ADJ
dpc-4976	86	16	and	and	CCONJ
dpc-4976	86	17	biopsy	biopsy	NOUN
dpc-4976	86	18	patients	patient	NOUN
dpc-4976	86	19	revealed	reveal	VERB
dpc-4976	86	20	no	no	DET
dpc-4976	86	21	significant	significant	ADJ
dpc-4976	86	22	differences	difference	NOUN
dpc-4976	86	23	between	between	ADP
dpc-4976	86	24	the	the	DET
dpc-4976	86	25	two	two	NUM
dpc-4976	86	26	groups	group	NOUN
dpc-4976	86	27	,	,	PUNCT
dpc-4976	86	28	although	although	SCONJ
dpc-4976	86	29	differences	difference	NOUN
dpc-4976	86	30	across	across	ADP
dpc-4976	86	31	timepoints	timepoint	NOUN
dpc-4976	86	32	were	be	AUX
dpc-4976	86	33	observed	observe	VERB
dpc-4976	86	34	.	.	PUNCT
dpc-4976	87	1	anova	anova	PROPN
dpc-4976	87	2	for	for	ADP
dpc-4976	87	3	repeated	repeat	VERB
dpc-4976	87	4	measures	measure	NOUN
dpc-4976	87	5	and	and	CCONJ
dpc-4976	87	6	ancova	ancova	NOUN
dpc-4976	87	7	analyses	analysis	NOUN
dpc-4976	87	8	were	be	AUX
dpc-4976	87	9	conducted	conduct	VERB
dpc-4976	87	10	.	.	PUNCT
dpc-4976	88	1	using	use	VERB
dpc-4976	88	2	the	the	DET
dpc-4976	88	3	baseline	baseline	ADJ
dpc-4976	88	4	pasi	pasi	NOUN
dpc-4976	88	5	score	score	NOUN
dpc-4976	88	6	as	as	ADP
dpc-4976	88	7	a	a	DET
dpc-4976	88	8	covariate	covariate	NOUN
dpc-4976	88	9	,	,	PUNCT
dpc-4976	88	10	the	the	DET
dpc-4976	88	11	p	p	NOUN
dpc-4976	88	12	-	-	PUNCT
dpc-4976	88	13	value	value	NOUN
dpc-4976	88	14	at	at	ADP
dpc-4976	88	15	week	week	NOUN
dpc-4976	88	16	4	4	NUM
dpc-4976	88	17	was	be	AUX
dpc-4976	88	18	less	less	ADJ
dpc-4976	88	19	than	than	ADP
dpc-4976	88	20	0.0001	0.0001	NUM
dpc-4976	88	21	,	,	PUNCT
dpc-4976	88	22	indicating	indicate	VERB
dpc-4976	88	23	a	a	DET
dpc-4976	88	24	significant	significant	ADJ
dpc-4976	88	25	difference	difference	NOUN
dpc-4976	88	26	from	from	ADP
dpc-4976	88	27	baseline	baseline	NOUN
dpc-4976	88	28	.	.	PUNCT
dpc-4976	89	1	at	at	ADP
dpc-4976	89	2	week	week	NOUN
dpc-4976	89	3	16	16	NUM
dpc-4976	89	4	,	,	PUNCT
dpc-4976	89	5	the	the	DET
dpc-4976	89	6	original	original	ADJ
dpc-4976	89	7	article	article	NOUN
dpc-4976	89	8	|	|	ADV
dpc-4976	89	9	dermatol	dermatol	ADJ
dpc-4976	89	10	pract	pract	NOUN
dpc-4976	89	11	concept	concept	NOUN
dpc-4976	89	12	.	.	PUNCT
dpc-4976	90	1	2025;15(1):4976	2025;15(1):4976	NUM
dpc-4976	90	2	5	5	NUM
dpc-4976	90	3	16	16	NUM
dpc-4976	90	4	,	,	PUNCT
dpc-4976	90	5	24	24	NUM
dpc-4976	90	6	,	,	PUNCT
dpc-4976	90	7	and	and	CCONJ
dpc-4976	90	8	54	54	NUM
dpc-4976	90	9	.	.	PUNCT
dpc-4976	91	1	these	these	DET
dpc-4976	91	2	changes	change	NOUN
dpc-4976	91	3	were	be	AUX
dpc-4976	91	4	also	also	ADV
dpc-4976	91	5	statistically	statistically	ADV
dpc-4976	91	6	significant	significant	ADJ
dpc-4976	91	7	at	at	ADP
dpc-4976	91	8	each	each	DET
dpc-4976	91	9	timepoint	timepoint	NOUN
dpc-4976	91	10	(	(	PUNCT
dpc-4976	91	11	p	p	NOUN
dpc-4976	91	12	-	-	PUNCT
dpc-4976	91	13	values	value	NOUN
dpc-4976	91	14	less	less	ADJ
dpc-4976	91	15	than	than	ADP
dpc-4976	91	16	0.0001	0.0001	NUM
dpc-4976	91	17	)	)	PUNCT
dpc-4976	91	18	(	(	PUNCT
dpc-4976	91	19	figure	figure	NOUN
dpc-4976	91	20	6	6	NUM
dpc-4976	91	21	)	)	PUNCT
dpc-4976	91	22	.	.	PUNCT
dpc-4976	92	1	for	for	ADP
dpc-4976	92	2	the	the	DET
dpc-4976	92	3	lower	low	ADJ
dpc-4976	92	4	limbs	limb	NOUN
dpc-4976	92	5	,	,	PUNCT
dpc-4976	92	6	mean	mean	ADJ
dpc-4976	92	7	pasi	pasi	NOUN
dpc-4976	92	8	subscores	subscore	NOUN
dpc-4976	92	9	were	be	AUX
dpc-4976	92	10	8.61	8.61	NUM
dpc-4976	92	11	at	at	ADP
dpc-4976	92	12	baseline	baseline	PROPN
dpc-4976	92	13	(	(	PUNCT
dpc-4976	92	14	n=104	n=104	PROPN
dpc-4976	92	15	)	)	PUNCT
dpc-4976	92	16	,	,	PUNCT
dpc-4976	92	17	decreasing	decrease	VERB
dpc-4976	92	18	to	to	ADP
dpc-4976	92	19	1.34	1.34	NUM
dpc-4976	92	20	at	at	ADP
dpc-4976	92	21	week	week	NOUN
dpc-4976	92	22	4	4	NUM
dpc-4976	92	23	(	(	PUNCT
dpc-4976	92	24	n=100	n=100	NUM
dpc-4976	92	25	)	)	PUNCT
dpc-4976	92	26	,	,	PUNCT
dpc-4976	92	27	0.21	0.21	NUM
dpc-4976	92	28	at	at	ADP
dpc-4976	92	29	week	week	NOUN
dpc-4976	92	30	16	16	NUM
dpc-4976	92	31	(	(	PUNCT
dpc-4976	92	32	n=92	n=92	PROPN
dpc-4976	92	33	)	)	PUNCT
dpc-4976	92	34	,	,	PUNCT
dpc-4976	92	35	0.03	0.03	NUM
dpc-4976	92	36	at	at	ADP
dpc-4976	92	37	week	week	NOUN
dpc-4976	92	38	24	24	NUM
dpc-4976	92	39	(	(	PUNCT
dpc-4976	92	40	n=69	n=69	X
dpc-4976	92	41	)	)	PUNCT
dpc-4976	92	42	,	,	PUNCT
dpc-4976	92	43	and	and	CCONJ
dpc-4976	92	44	slightly	slightly	ADV
dpc-4976	92	45	increasing	increase	VERB
dpc-4976	92	46	to	to	ADP
dpc-4976	92	47	0.12	0.12	NUM
dpc-4976	92	48	at	at	ADP
dpc-4976	92	49	week	week	NOUN
dpc-4976	92	50	54	54	NUM
dpc-4976	92	51	(	(	PUNCT
dpc-4976	92	52	n=26	n=26	PROPN
dpc-4976	92	53	)	)	PUNCT
dpc-4976	92	54	.	.	PUNCT
dpc-4976	93	1	pasi	pasi	NOUN
dpc-4976	93	2	100	100	NUM
dpc-4976	93	3	achievement	achievement	NOUN
dpc-4976	93	4	rates	rate	NOUN
dpc-4976	93	5	for	for	ADP
dpc-4976	93	6	the	the	DET
dpc-4976	93	7	lower	low	ADJ
dpc-4976	93	8	limbs	limb	NOUN
dpc-4976	93	9	were	be	AUX
dpc-4976	93	10	53	53	NUM
dpc-4976	93	11	%	%	NOUN
dpc-4976	93	12	at	at	ADP
dpc-4976	93	13	week	week	NOUN
dpc-4976	93	14	4	4	NUM
dpc-4976	93	15	,	,	PUNCT
dpc-4976	93	16	94	94	NUM
dpc-4976	93	17	%	%	NOUN
dpc-4976	93	18	at	at	ADP
dpc-4976	93	19	week	week	NOUN
dpc-4976	93	20	16	16	NUM
dpc-4976	93	21	,	,	PUNCT
dpc-4976	93	22	91	91	NUM
dpc-4976	93	23	%	%	NOUN
dpc-4976	93	24	at	at	ADP
dpc-4976	93	25	week	week	NOUN
dpc-4976	93	26	24	24	NUM
dpc-4976	93	27	,	,	PUNCT
dpc-4976	93	28	and	and	CCONJ
dpc-4976	93	29	92	92	NUM
dpc-4976	93	30	%	%	NOUN
dpc-4976	93	31	at	at	ADP
dpc-4976	93	32	week	week	NOUN
dpc-4976	93	33	54	54	NUM
dpc-4976	93	34	.	.	PUNCT
dpc-4976	94	1	these	these	DET
dpc-4976	94	2	changes	change	NOUN
dpc-4976	94	3	were	be	AUX
dpc-4976	94	4	statistically	statistically	ADV
dpc-4976	94	5	significant	significant	ADJ
dpc-4976	94	6	at	at	ADP
dpc-4976	94	7	each	each	DET
dpc-4976	94	8	timepoint	timepoint	NOUN
dpc-4976	94	9	(	(	PUNCT
dpc-4976	94	10	p	p	NOUN
dpc-4976	94	11	-	-	PUNCT
dpc-4976	94	12	values	value	NOUN
dpc-4976	94	13	less	less	ADJ
dpc-4976	94	14	than	than	ADP
dpc-4976	94	15	0.0001	0.0001	NUM
dpc-4976	94	16	)	)	PUNCT
dpc-4976	94	17	(	(	PUNCT
dpc-4976	94	18	figure	figure	NOUN
dpc-4976	94	19	7	7	NUM
dpc-4976	94	20	)	)	PUNCT
dpc-4976	94	21	.	.	PUNCT
dpc-4976	95	1	quality	quality	NOUN
dpc-4976	95	2	of	of	ADP
dpc-4976	95	3	life	life	NOUN
dpc-4976	95	4	for	for	ADP
dpc-4976	95	5	all	all	DET
dpc-4976	95	6	enrolled	enrol	VERB
dpc-4976	95	7	patients	patient	NOUN
dpc-4976	95	8	,	,	PUNCT
dpc-4976	95	9	the	the	DET
dpc-4976	95	10	mean	mean	ADJ
dpc-4976	95	11	dlqi	dlqi	ADJ
dpc-4976	95	12	score	score	NOUN
dpc-4976	95	13	at	at	ADP
dpc-4976	95	14	baseline	baseline	PROPN
dpc-4976	95	15	was	be	AUX
dpc-4976	95	16	13.57	13.57	NUM
dpc-4976	95	17	(	(	PUNCT
dpc-4976	95	18	n=96	n=96	PROPN
dpc-4976	95	19	)	)	PUNCT
dpc-4976	95	20	,	,	PUNCT
dpc-4976	95	21	which	which	PRON
dpc-4976	95	22	significantly	significantly	ADV
dpc-4976	95	23	decreased	decrease	VERB
dpc-4976	95	24	to	to	ADP
dpc-4976	95	25	0.86	0.86	NUM
dpc-4976	95	26	at	at	ADP
dpc-4976	95	27	week	week	NOUN
dpc-4976	95	28	16	16	NUM
dpc-4976	95	29	(	(	PUNCT
dpc-4976	95	30	n=87	n=87	PROPN
dpc-4976	95	31	)	)	PUNCT
dpc-4976	95	32	(	(	PUNCT
dpc-4976	95	33	figure	figure	NOUN
dpc-4976	95	34	s3	s3	PROPN
dpc-4976	95	35	)	)	PUNCT
dpc-4976	95	36	.	.	PUNCT
dpc-4976	96	1	discussion	discussion	NOUN
dpc-4976	96	2	psoriasis	psoriasis	NOUN
dpc-4976	96	3	is	be	AUX
dpc-4976	96	4	a	a	DET
dpc-4976	96	5	chronic	chronic	NOUN
dpc-4976	96	6	,	,	PUNCT
dpc-4976	96	7	immune	immune	NOUN
dpc-4976	96	8	-	-	PUNCT
dpc-4976	96	9	mediated	mediate	VERB
dpc-4976	96	10	inflammatory	inflammatory	ADJ
dpc-4976	96	11	skin	skin	NOUN
dpc-4976	96	12	disease	disease	NOUN
dpc-4976	96	13	affecting	affect	VERB
dpc-4976	96	14	around	around	ADP
dpc-4976	96	15	2	2	NUM
dpc-4976	96	16	%	%	NOUN
dpc-4976	96	17	of	of	ADP
dpc-4976	96	18	people	people	NOUN
dpc-4976	96	19	in	in	ADP
dpc-4976	96	20	europe	europe	PROPN
dpc-4976	96	21	and	and	CCONJ
dpc-4976	96	22	north	north	PROPN
dpc-4976	96	23	america	america	PROPN
dpc-4976	97	1	[	[	X
dpc-4976	97	2	8	8	NUM
dpc-4976	97	3	]	]	PUNCT
dpc-4976	97	4	.	.	PUNCT
dpc-4976	98	1	stress	stress	NOUN
dpc-4976	98	2	significantly	significantly	ADV
dpc-4976	98	3	contributes	contribute	VERB
dpc-4976	98	4	to	to	ADP
dpc-4976	98	5	its	its	PRON
dpc-4976	98	6	onset	onset	NOUN
dpc-4976	98	7	and	and	CCONJ
dpc-4976	98	8	exacerbation	exacerbation	NOUN
dpc-4976	98	9	,	,	PUNCT
dpc-4976	98	10	highlighting	highlight	VERB
dpc-4976	98	11	the	the	DET
dpc-4976	98	12	importance	importance	NOUN
dpc-4976	98	13	of	of	ADP
dpc-4976	98	14	addressing	address	VERB
dpc-4976	98	15	both	both	CCONJ
dpc-4976	98	16	the	the	DET
dpc-4976	98	17	clinical	clinical	ADJ
dpc-4976	98	18	and	and	CCONJ
dpc-4976	98	19	psychosocial	psychosocial	ADJ
dpc-4976	98	20	aspects	aspect	NOUN
dpc-4976	98	21	of	of	ADP
dpc-4976	98	22	the	the	DET
dpc-4976	98	23	condition	condition	NOUN
dpc-4976	98	24	[	[	X
dpc-4976	98	25	9	9	NUM
dpc-4976	98	26	]	]	PUNCT
dpc-4976	98	27	.	.	PUNCT
dpc-4976	99	1	effective	effective	ADJ
dpc-4976	99	2	management	management	NOUN
dpc-4976	99	3	is	be	AUX
dpc-4976	99	4	essential	essential	ADJ
dpc-4976	99	5	,	,	PUNCT
dpc-4976	99	6	especially	especially	ADV
dpc-4976	99	7	with	with	ADP
dpc-4976	99	8	advancements	advancement	NOUN
dpc-4976	99	9	in	in	ADP
dpc-4976	99	10	treatment	treatment	NOUN
dpc-4976	99	11	options	option	NOUN
dpc-4976	99	12	like	like	ADP
dpc-4976	99	13	biologics	biologic	NOUN
dpc-4976	99	14	that	that	PRON
dpc-4976	99	15	target	target	VERB
dpc-4976	99	16	specific	specific	ADJ
dpc-4976	99	17	cytokines	cytokine	NOUN
dpc-4976	99	18	,	,	PUNCT
dpc-4976	99	19	which	which	PRON
dpc-4976	99	20	have	have	AUX
dpc-4976	99	21	improved	improve	VERB
dpc-4976	99	22	psoriasis	psoriasis	NOUN
dpc-4976	99	23	management	management	NOUN
dpc-4976	99	24	over	over	ADP
dpc-4976	99	25	the	the	DET
dpc-4976	99	26	past	past	ADJ
dpc-4976	99	27	decade	decade	NOUN
dpc-4976	99	28	[	[	X
dpc-4976	99	29	10	10	NUM
dpc-4976	99	30	]	]	PUNCT
dpc-4976	99	31	.	.	PUNCT
dpc-4976	100	1	bimekizumab	bimekizumab	PROPN
dpc-4976	100	2	is	be	AUX
dpc-4976	100	3	one	one	NUM
dpc-4976	100	4	such	such	ADJ
dpc-4976	100	5	promising	promising	ADJ
dpc-4976	100	6	treatment	treatment	NOUN
dpc-4976	100	7	for	for	ADP
dpc-4976	100	8	moderate	moderate	ADJ
dpc-4976	100	9	-	-	PUNCT
dpc-4976	100	10	to	to	ADP
dpc-4976	100	11	-	-	PUNCT
dpc-4976	100	12	severe	severe	ADJ
dpc-4976	100	13	psoriasis	psoriasis	NOUN
dpc-4976	100	14	,	,	PUNCT
dpc-4976	100	15	offering	offer	VERB
dpc-4976	100	16	high	high	ADJ
dpc-4976	100	17	efficacy	efficacy	NOUN
dpc-4976	100	18	and	and	CCONJ
dpc-4976	100	19	safety	safety	NOUN
dpc-4976	100	20	[	[	X
dpc-4976	100	21	7,11–13	7,11–13	X
dpc-4976	100	22	]	]	X
dpc-4976	100	23	,	,	PUNCT
dpc-4976	100	24	though	though	SCONJ
dpc-4976	100	25	real	real	ADJ
dpc-4976	100	26	-	-	PUNCT
dpc-4976	100	27	world	world	NOUN
dpc-4976	100	28	evidence	evidence	NOUN
dpc-4976	100	29	is	be	AUX
dpc-4976	100	30	still	still	ADV
dpc-4976	100	31	limited	limit	VERB
dpc-4976	100	32	[	[	PUNCT
dpc-4976	100	33	7	7	NUM
dpc-4976	100	34	]	]	PUNCT
dpc-4976	100	35	.	.	PUNCT
dpc-4976	101	1	p	p	X
dpc-4976	101	2	-	-	PUNCT
dpc-4976	101	3	value	value	NOUN
dpc-4976	101	4	was	be	AUX
dpc-4976	101	5	0.0012	0.0012	NUM
dpc-4976	101	6	,	,	PUNCT
dpc-4976	101	7	also	also	ADV
dpc-4976	101	8	indicating	indicate	VERB
dpc-4976	101	9	significance	significance	NOUN
dpc-4976	101	10	.	.	PUNCT
dpc-4976	102	1	however	however	ADV
dpc-4976	102	2	,	,	PUNCT
dpc-4976	102	3	at	at	ADP
dpc-4976	102	4	week	week	NOUN
dpc-4976	102	5	24	24	NUM
dpc-4976	102	6	,	,	PUNCT
dpc-4976	102	7	the	the	DET
dpc-4976	102	8	p	p	NOUN
dpc-4976	102	9	-	-	PUNCT
dpc-4976	102	10	value	value	NOUN
dpc-4976	102	11	was	be	AUX
dpc-4976	102	12	0.1590	0.1590	NUM
dpc-4976	102	13	,	,	PUNCT
dpc-4976	102	14	showing	show	VERB
dpc-4976	102	15	no	no	DET
dpc-4976	102	16	significant	significant	ADJ
dpc-4976	102	17	change	change	NOUN
dpc-4976	102	18	,	,	PUNCT
dpc-4976	102	19	while	while	SCONJ
dpc-4976	102	20	at	at	ADP
dpc-4976	102	21	week	week	NOUN
dpc-4976	102	22	54	54	NUM
dpc-4976	102	23	,	,	PUNCT
dpc-4976	102	24	the	the	DET
dpc-4976	102	25	p	p	NOUN
dpc-4976	102	26	-	-	PUNCT
dpc-4976	102	27	value	value	NOUN
dpc-4976	102	28	was	be	AUX
dpc-4976	102	29	0.0041	0.0041	NUM
dpc-4976	102	30	,	,	PUNCT
dpc-4976	102	31	indicating	indicate	VERB
dpc-4976	102	32	a	a	DET
dpc-4976	102	33	significant	significant	ADJ
dpc-4976	102	34	difference	difference	NOUN
dpc-4976	102	35	from	from	ADP
dpc-4976	102	36	baseline	baseline	NOUN
dpc-4976	102	37	.	.	PUNCT
dpc-4976	103	1	when	when	SCONJ
dpc-4976	103	2	comparing	compare	VERB
dpc-4976	103	3	bio	bio	ADJ
dpc-4976	103	4	-	-	ADJ
dpc-4976	103	5	naive	naive	ADJ
dpc-4976	103	6	and	and	CCONJ
dpc-4976	103	7	bio	bio	ADJ
dpc-4976	103	8	-	-	ADJ
dpc-4976	103	9	experienced	experienced	ADJ
dpc-4976	103	10	patients	patient	NOUN
dpc-4976	103	11	,	,	PUNCT
dpc-4976	103	12	the	the	DET
dpc-4976	103	13	p	p	NOUN
dpc-4976	103	14	-	-	PUNCT
dpc-4976	103	15	values	value	NOUN
dpc-4976	103	16	were	be	AUX
dpc-4976	103	17	as	as	SCONJ
dpc-4976	103	18	follows	follow	VERB
dpc-4976	103	19	:	:	PUNCT
dpc-4976	103	20	0.4230	0.4230	NUM
dpc-4976	103	21	at	at	ADP
dpc-4976	103	22	week	week	NOUN
dpc-4976	103	23	4	4	NUM
dpc-4976	103	24	,	,	PUNCT
dpc-4976	103	25	0.1285	0.1285	NUM
dpc-4976	103	26	at	at	ADP
dpc-4976	103	27	week	week	NOUN
dpc-4976	103	28	16	16	NUM
dpc-4976	103	29	,	,	PUNCT
dpc-4976	103	30	0.5384	0.5384	NUM
dpc-4976	103	31	at	at	ADP
dpc-4976	103	32	week	week	NOUN
dpc-4976	103	33	24	24	NUM
dpc-4976	103	34	,	,	PUNCT
dpc-4976	103	35	and	and	CCONJ
dpc-4976	103	36	0.2781	0.2781	NUM
dpc-4976	103	37	at	at	ADP
dpc-4976	103	38	week	week	NOUN
dpc-4976	103	39	54	54	NUM
dpc-4976	103	40	,	,	PUNCT
dpc-4976	103	41	indicating	indicate	VERB
dpc-4976	103	42	no	no	DET
dpc-4976	103	43	significant	significant	ADJ
dpc-4976	103	44	differences	difference	NOUN
dpc-4976	103	45	between	between	ADP
dpc-4976	103	46	the	the	DET
dpc-4976	103	47	groups	group	NOUN
dpc-4976	103	48	at	at	ADP
dpc-4976	103	49	any	any	DET
dpc-4976	103	50	timepoint	timepoint	NOUN
dpc-4976	103	51	.	.	PUNCT
dpc-4976	104	1	pasi	pasi	NOUN
dpc-4976	104	2	subscores	subscore	NOUN
dpc-4976	104	3	according	accord	VERB
dpc-4976	104	4	to	to	ADP
dpc-4976	104	5	different	different	ADJ
dpc-4976	104	6	body	body	NOUN
dpc-4976	104	7	areas	area	NOUN
dpc-4976	104	8	:	:	PUNCT
dpc-4976	104	9	for	for	ADP
dpc-4976	104	10	all	all	DET
dpc-4976	104	11	enrolled	enrol	VERB
dpc-4976	104	12	patients	patient	NOUN
dpc-4976	104	13	,	,	PUNCT
dpc-4976	104	14	the	the	DET
dpc-4976	104	15	mean	mean	ADJ
dpc-4976	104	16	pasi	pasi	NOUN
dpc-4976	104	17	subscores	subscore	NOUN
dpc-4976	104	18	for	for	ADP
dpc-4976	104	19	the	the	DET
dpc-4976	104	20	head	head	NOUN
dpc-4976	104	21	were	be	AUX
dpc-4976	104	22	3.24	3.24	NUM
dpc-4976	104	23	at	at	ADP
dpc-4976	104	24	baseline	baseline	PROPN
dpc-4976	104	25	(	(	PUNCT
dpc-4976	104	26	n=49	n=49	NUM
dpc-4976	104	27	)	)	PUNCT
dpc-4976	104	28	,	,	PUNCT
dpc-4976	104	29	decreasing	decrease	VERB
dpc-4976	104	30	to	to	ADP
dpc-4976	104	31	0.51	0.51	NUM
dpc-4976	104	32	at	at	ADP
dpc-4976	104	33	week	week	NOUN
dpc-4976	104	34	4	4	NUM
dpc-4976	104	35	(	(	PUNCT
dpc-4976	104	36	n=49	n=49	NUM
dpc-4976	104	37	)	)	PUNCT
dpc-4976	104	38	,	,	PUNCT
dpc-4976	104	39	0.19	0.19	NUM
dpc-4976	104	40	at	at	ADP
dpc-4976	104	41	week	week	NOUN
dpc-4976	104	42	16	16	NUM
dpc-4976	104	43	(	(	PUNCT
dpc-4976	104	44	n=48	n=48	NOUN
dpc-4976	104	45	)	)	PUNCT
dpc-4976	104	46	,	,	PUNCT
dpc-4976	104	47	0.21	0.21	NUM
dpc-4976	104	48	at	at	ADP
dpc-4976	104	49	week	week	NOUN
dpc-4976	104	50	24	24	NUM
dpc-4976	104	51	(	(	PUNCT
dpc-4976	104	52	n=42	n=42	NOUN
dpc-4976	104	53	)	)	PUNCT
dpc-4976	104	54	,	,	PUNCT
dpc-4976	104	55	and	and	CCONJ
dpc-4976	104	56	0.13	0.13	NUM
dpc-4976	104	57	at	at	ADP
dpc-4976	104	58	week	week	NOUN
dpc-4976	104	59	54	54	NUM
dpc-4976	104	60	(	(	PUNCT
dpc-4976	104	61	n=24	n=24	PROPN
dpc-4976	104	62	)	)	PUNCT
dpc-4976	104	63	.	.	PUNCT
dpc-4976	105	1	the	the	DET
dpc-4976	105	2	percentage	percentage	NOUN
dpc-4976	105	3	of	of	ADP
dpc-4976	105	4	patients	patient	NOUN
dpc-4976	105	5	achieving	achieve	VERB
dpc-4976	105	6	pasi	pasi	NOUN
dpc-4976	105	7	100	100	NUM
dpc-4976	105	8	(	(	PUNCT
dpc-4976	105	9	complete	complete	ADJ
dpc-4976	105	10	skin	skin	NOUN
dpc-4976	105	11	clearance	clearance	NOUN
dpc-4976	105	12	)	)	PUNCT
dpc-4976	105	13	for	for	ADP
dpc-4976	105	14	the	the	DET
dpc-4976	105	15	head	head	NOUN
dpc-4976	105	16	improved	improve	VERB
dpc-4976	105	17	over	over	ADP
dpc-4976	105	18	time	time	NOUN
dpc-4976	105	19	:	:	PUNCT
dpc-4976	105	20	67	67	NUM
dpc-4976	105	21	%	%	NOUN
dpc-4976	105	22	at	at	ADP
dpc-4976	105	23	week	week	NOUN
dpc-4976	105	24	4	4	NUM
dpc-4976	105	25	,	,	PUNCT
dpc-4976	105	26	85	85	NUM
dpc-4976	105	27	%	%	NOUN
dpc-4976	105	28	at	at	ADP
dpc-4976	105	29	week	week	NOUN
dpc-4976	105	30	16	16	NUM
dpc-4976	105	31	,	,	PUNCT
dpc-4976	105	32	86	86	NUM
dpc-4976	105	33	%	%	NOUN
dpc-4976	105	34	at	at	ADP
dpc-4976	105	35	week	week	NOUN
dpc-4976	105	36	24	24	NUM
dpc-4976	105	37	,	,	PUNCT
dpc-4976	105	38	and	and	CCONJ
dpc-4976	105	39	85	85	NUM
dpc-4976	105	40	%	%	NOUN
dpc-4976	105	41	at	at	ADP
dpc-4976	105	42	week	week	NOUN
dpc-4976	105	43	54	54	NUM
dpc-4976	105	44	(	(	PUNCT
dpc-4976	105	45	figure	figure	NOUN
dpc-4976	105	46	4	4	NUM
dpc-4976	105	47	)	)	PUNCT
dpc-4976	105	48	.	.	PUNCT
dpc-4976	106	1	for	for	ADP
dpc-4976	106	2	the	the	DET
dpc-4976	106	3	upper	upper	ADJ
dpc-4976	106	4	limbs	limb	NOUN
dpc-4976	106	5	,	,	PUNCT
dpc-4976	106	6	mean	mean	ADJ
dpc-4976	106	7	pasi	pasi	NOUN
dpc-4976	106	8	subscores	subscore	NOUN
dpc-4976	106	9	were	be	AUX
dpc-4976	106	10	8.49	8.49	NUM
dpc-4976	106	11	at	at	ADP
dpc-4976	106	12	baseline	baseline	PROPN
dpc-4976	106	13	(	(	PUNCT
dpc-4976	106	14	n=109	n=109	NUM
dpc-4976	106	15	)	)	PUNCT
dpc-4976	106	16	,	,	PUNCT
dpc-4976	106	17	decreasing	decrease	VERB
dpc-4976	106	18	to	to	ADP
dpc-4976	106	19	1.25	1.25	NUM
dpc-4976	106	20	at	at	ADP
dpc-4976	106	21	week	week	NOUN
dpc-4976	106	22	4	4	NUM
dpc-4976	106	23	(	(	PUNCT
dpc-4976	106	24	n=106	n=106	NOUN
dpc-4976	106	25	)	)	PUNCT
dpc-4976	106	26	,	,	PUNCT
dpc-4976	106	27	0.25	0.25	NUM
dpc-4976	106	28	at	at	ADP
dpc-4976	106	29	week	week	NOUN
dpc-4976	106	30	16	16	NUM
dpc-4976	106	31	(	(	PUNCT
dpc-4976	106	32	n=99	n=99	ADJ
dpc-4976	106	33	)	)	PUNCT
dpc-4976	106	34	,	,	PUNCT
dpc-4976	106	35	0.09	0.09	NUM
dpc-4976	106	36	at	at	ADP
dpc-4976	106	37	week	week	NOUN
dpc-4976	106	38	24	24	NUM
dpc-4976	106	39	(	(	PUNCT
dpc-4976	106	40	n=75	n=75	PROPN
dpc-4976	106	41	)	)	PUNCT
dpc-4976	106	42	,	,	PUNCT
dpc-4976	106	43	and	and	CCONJ
dpc-4976	106	44	0	0	NUM
dpc-4976	106	45	at	at	ADP
dpc-4976	106	46	week	week	NOUN
dpc-4976	106	47	54	54	NUM
dpc-4976	106	48	(	(	PUNCT
dpc-4976	106	49	n=28	n=28	NOUN
dpc-4976	106	50	)	)	PUNCT
dpc-4976	106	51	.	.	PUNCT
dpc-4976	107	1	the	the	DET
dpc-4976	107	2	percentage	percentage	NOUN
dpc-4976	107	3	of	of	ADP
dpc-4976	107	4	patients	patient	NOUN
dpc-4976	107	5	achieving	achieve	VERB
dpc-4976	107	6	pasi	pasi	NOUN
dpc-4976	107	7	100	100	NUM
dpc-4976	107	8	for	for	ADP
dpc-4976	107	9	the	the	DET
dpc-4976	107	10	upper	upper	ADJ
dpc-4976	107	11	limbs	limb	NOUN
dpc-4976	107	12	steadily	steadily	ADV
dpc-4976	107	13	increased	increase	VERB
dpc-4976	107	14	:	:	PUNCT
dpc-4976	107	15	53	53	NUM
dpc-4976	107	16	%	%	NOUN
dpc-4976	107	17	at	at	ADP
dpc-4976	107	18	week	week	NOUN
dpc-4976	107	19	4	4	NUM
dpc-4976	107	20	,	,	PUNCT
dpc-4976	107	21	90	90	NUM
dpc-4976	107	22	%	%	NOUN
dpc-4976	107	23	at	at	ADP
dpc-4976	107	24	week	week	NOUN
dpc-4976	107	25	16	16	NUM
dpc-4976	107	26	,	,	PUNCT
dpc-4976	107	27	90	90	NUM
dpc-4976	107	28	%	%	NOUN
dpc-4976	107	29	at	at	ADP
dpc-4976	107	30	week	week	NOUN
dpc-4976	107	31	24	24	NUM
dpc-4976	107	32	,	,	PUNCT
dpc-4976	107	33	and	and	CCONJ
dpc-4976	107	34	97	97	NUM
dpc-4976	107	35	%	%	NOUN
dpc-4976	107	36	at	at	ADP
dpc-4976	107	37	week	week	NOUN
dpc-4976	107	38	54	54	NUM
dpc-4976	107	39	.	.	PUNCT
dpc-4976	108	1	these	these	DET
dpc-4976	108	2	changes	change	NOUN
dpc-4976	108	3	were	be	AUX
dpc-4976	108	4	statistically	statistically	ADV
dpc-4976	108	5	significant	significant	ADJ
dpc-4976	108	6	at	at	ADP
dpc-4976	108	7	all	all	DET
dpc-4976	108	8	timepoints	timepoint	NOUN
dpc-4976	108	9	,	,	PUNCT
dpc-4976	108	10	with	with	ADP
dpc-4976	108	11	p	p	NOUN
dpc-4976	108	12	-	-	PUNCT
dpc-4976	108	13	values	value	NOUN
dpc-4976	108	14	less	less	ADJ
dpc-4976	108	15	than	than	ADP
dpc-4976	108	16	0.0001	0.0001	NUM
dpc-4976	108	17	(	(	PUNCT
dpc-4976	108	18	figure	figure	NOUN
dpc-4976	108	19	5	5	NUM
dpc-4976	108	20	)	)	PUNCT
dpc-4976	108	21	.	.	PUNCT
dpc-4976	109	1	for	for	ADP
dpc-4976	109	2	the	the	DET
dpc-4976	109	3	trunk	trunk	NOUN
dpc-4976	109	4	,	,	PUNCT
dpc-4976	109	5	mean	mean	ADJ
dpc-4976	109	6	pasi	pasi	NOUN
dpc-4976	109	7	subscores	subscore	NOUN
dpc-4976	109	8	were	be	AUX
dpc-4976	109	9	8.35	8.35	NUM
dpc-4976	109	10	at	at	ADP
dpc-4976	109	11	baseline	baseline	PROPN
dpc-4976	109	12	(	(	PUNCT
dpc-4976	109	13	n=110	n=110	PROPN
dpc-4976	109	14	)	)	PUNCT
dpc-4976	109	15	,	,	PUNCT
dpc-4976	109	16	decreasing	decrease	VERB
dpc-4976	109	17	to	to	ADP
dpc-4976	109	18	1.32	1.32	NUM
dpc-4976	109	19	at	at	ADP
dpc-4976	109	20	week	week	NOUN
dpc-4976	109	21	4	4	NUM
dpc-4976	109	22	(	(	PUNCT
dpc-4976	109	23	n=108	n=108	PROPN
dpc-4976	109	24	)	)	PUNCT
dpc-4976	109	25	,	,	PUNCT
dpc-4976	109	26	0.22	0.22	NUM
dpc-4976	109	27	at	at	ADP
dpc-4976	109	28	week	week	NOUN
dpc-4976	109	29	16	16	NUM
dpc-4976	109	30	(	(	PUNCT
dpc-4976	109	31	n=101	n=101	PROPN
dpc-4976	109	32	)	)	PUNCT
dpc-4976	109	33	,	,	PUNCT
dpc-4976	109	34	and	and	CCONJ
dpc-4976	109	35	0.03	0.03	NUM
dpc-4976	109	36	at	at	ADP
dpc-4976	109	37	both	both	DET
dpc-4976	109	38	weeks	week	NOUN
dpc-4976	109	39	24	24	NUM
dpc-4976	109	40	(	(	PUNCT
dpc-4976	109	41	n=77	n=77	PROPN
dpc-4976	109	42	)	)	PUNCT
dpc-4976	109	43	and	and	CCONJ
dpc-4976	109	44	54	54	NUM
dpc-4976	109	45	(	(	PUNCT
dpc-4976	109	46	n=32	n=32	PROPN
dpc-4976	109	47	)	)	PUNCT
dpc-4976	109	48	.	.	PUNCT
dpc-4976	110	1	the	the	DET
dpc-4976	110	2	percentage	percentage	NOUN
dpc-4976	110	3	of	of	ADP
dpc-4976	110	4	patients	patient	NOUN
dpc-4976	110	5	achieving	achieve	VERB
dpc-4976	110	6	pasi	pasi	NOUN
dpc-4976	110	7	100	100	NUM
dpc-4976	110	8	for	for	ADP
dpc-4976	110	9	the	the	DET
dpc-4976	110	10	trunk	trunk	NOUN
dpc-4976	110	11	increased	increase	VERB
dpc-4976	110	12	from	from	ADP
dpc-4976	110	13	52	52	NUM
dpc-4976	110	14	%	%	NOUN
dpc-4976	110	15	at	at	ADP
dpc-4976	110	16	week	week	NOUN
dpc-4976	110	17	4	4	NUM
dpc-4976	110	18	to	to	PART
dpc-4976	110	19	94	94	NUM
dpc-4976	110	20	%	%	NOUN
dpc-4976	110	21	at	at	ADP
dpc-4976	110	22	weeks	week	NOUN
dpc-4976	110	23	figure	figure	NOUN
dpc-4976	110	24	3	3	NUM
dpc-4976	110	25	.	.	NOUN
dpc-4976	110	26	percentage	percentage	NOUN
dpc-4976	110	27	of	of	ADP
dpc-4976	110	28	patients	patient	NOUN
dpc-4976	110	29	with	with	ADP
dpc-4976	110	30	pasi	pasi	NOUN
dpc-4976	110	31	subscore	subscore	ADV
dpc-4976	110	32	of	of	ADP
dpc-4976	110	33	0	0	NUM
dpc-4976	110	34	over	over	ADP
dpc-4976	110	35	time	time	NOUN
dpc-4976	110	36	.	.	PUNCT
dpc-4976	111	1	patients	patient	NOUN
dpc-4976	111	2	achieving	achieve	VERB
dpc-4976	111	3	a	a	DET
dpc-4976	111	4	pasi	pasi	NOUN
dpc-4976	111	5	subscore	subscore	ADV
dpc-4976	111	6	of	of	ADP
dpc-4976	111	7	0	0	NUM
dpc-4976	111	8	(	(	PUNCT
dpc-4976	111	9	indicating	indicate	VERB
dpc-4976	111	10	no	no	DET
dpc-4976	111	11	psoriasis	psoriasis	NOUN
dpc-4976	111	12	)	)	PUNCT
dpc-4976	111	13	in	in	ADP
dpc-4976	111	14	different	different	ADJ
dpc-4976	111	15	body	body	NOUN
dpc-4976	111	16	areas	area	NOUN
dpc-4976	111	17	(	(	PUNCT
dpc-4976	111	18	head	head	NOUN
dpc-4976	111	19	,	,	PUNCT
dpc-4976	111	20	upper	upper	ADJ
dpc-4976	111	21	limb	limb	NOUN
dpc-4976	111	22	,	,	PUNCT
dpc-4976	111	23	trunk	trunk	NOUN
dpc-4976	111	24	,	,	PUNCT
dpc-4976	111	25	lower	low	ADJ
dpc-4976	111	26	limb	limb	NOUN
dpc-4976	111	27	)	)	PUNCT
dpc-4976	111	28	over	over	ADP
dpc-4976	111	29	time	time	NOUN
dpc-4976	111	30	for	for	ADP
dpc-4976	111	31	all	all	DET
dpc-4976	111	32	enrolled	enrol	VERB
dpc-4976	111	33	patients	patient	NOUN
dpc-4976	111	34	.	.	PUNCT
dpc-4976	112	1	the	the	DET
dpc-4976	112	2	percentages	percentage	NOUN
dpc-4976	112	3	were	be	AUX
dpc-4976	112	4	recorded	record	VERB
dpc-4976	112	5	at	at	ADP
dpc-4976	112	6	week	week	NOUN
dpc-4976	112	7	4	4	NUM
dpc-4976	112	8	(	(	PUNCT
dpc-4976	112	9	w4	w4	NOUN
dpc-4976	112	10	)	)	PUNCT
dpc-4976	112	11	,	,	PUNCT
dpc-4976	112	12	week	week	NOUN
dpc-4976	112	13	16	16	NUM
dpc-4976	112	14	(	(	PUNCT
dpc-4976	112	15	w16	w16	NOUN
dpc-4976	112	16	)	)	PUNCT
dpc-4976	112	17	,	,	PUNCT
dpc-4976	112	18	week	week	NOUN
dpc-4976	112	19	24	24	NUM
dpc-4976	112	20	(	(	PUNCT
dpc-4976	112	21	w24	w24	PROPN
dpc-4976	112	22	)	)	PUNCT
dpc-4976	112	23	,	,	PUNCT
dpc-4976	112	24	and	and	CCONJ
dpc-4976	112	25	week	week	NOUN
dpc-4976	112	26	52	52	NUM
dpc-4976	112	27	(	(	PUNCT
dpc-4976	112	28	w52	w52	NOUN
dpc-4976	112	29	)	)	PUNCT
dpc-4976	112	30	.	.	PUNCT
dpc-4976	113	1	6	6	NUM
dpc-4976	113	2	original	original	ADJ
dpc-4976	113	3	article	article	NOUN
dpc-4976	113	4	|	|	ADV
dpc-4976	113	5	dermatol	dermatol	ADJ
dpc-4976	113	6	pract	pract	NOUN
dpc-4976	113	7	concept	concept	NOUN
dpc-4976	113	8	.	.	PUNCT
dpc-4976	114	1	2025;15(1):4976	2025;15(1):4976	PROPN
dpc-4976	114	2	pasi	pasi	NOUN
dpc-4976	114	3	75	75	NUM
dpc-4976	114	4	,	,	PUNCT
dpc-4976	114	5	further	far	ADV
dpc-4976	114	6	highlighting	highlight	VERB
dpc-4976	114	7	bimekizumab	bimekizumab	NOUN
dpc-4976	114	8	’s	’s	PART
dpc-4976	114	9	robust	robust	ADJ
dpc-4976	114	10	efficacy	efficacy	NOUN
dpc-4976	114	11	in	in	ADP
dpc-4976	114	12	a	a	DET
dpc-4976	114	13	real	real	ADJ
dpc-4976	114	14	-	-	PUNCT
dpc-4976	114	15	world	world	NOUN
dpc-4976	114	16	setting	setting	NOUN
dpc-4976	114	17	[	[	X
dpc-4976	114	18	7	7	NUM
dpc-4976	114	19	]	]	PUNCT
dpc-4976	114	20	.	.	PUNCT
dpc-4976	115	1	recently	recently	ADV
dpc-4976	115	2	,	,	PUNCT
dpc-4976	115	3	a	a	DET
dpc-4976	115	4	real	real	ADJ
dpc-4976	115	5	-	-	PUNCT
dpc-4976	115	6	world	world	NOUN
dpc-4976	115	7	,	,	PUNCT
dpc-4976	115	8	multicenter	multicenter	NOUN
dpc-4976	115	9	retrospective	retrospective	ADJ
dpc-4976	115	10	study	study	NOUN
dpc-4976	115	11	conducted	conduct	VERB
dpc-4976	115	12	by	by	ADP
dpc-4976	115	13	orsini	orsini	PROPN
dpc-4976	115	14	et	et	PROPN
dpc-4976	115	15	al	al	PROPN
dpc-4976	115	16	.	.	PROPN
dpc-4976	115	17	evaluated	evaluate	VERB
dpc-4976	115	18	the	the	DET
dpc-4976	115	19	efficacy	efficacy	NOUN
dpc-4976	115	20	and	and	CCONJ
dpc-4976	115	21	safety	safety	NOUN
dpc-4976	115	22	of	of	ADP
dpc-4976	115	23	bimekizumab	bimekizumab	NOUN
dpc-4976	115	24	in	in	ADP
dpc-4976	115	25	98	98	NUM
dpc-4976	115	26	elderly	elderly	ADJ
dpc-4976	115	27	patients	patient	NOUN
dpc-4976	115	28	(	(	PUNCT
dpc-4976	115	29	≥65	≥65	NUM
dpc-4976	115	30	years	year	NOUN
dpc-4976	115	31	)	)	PUNCT
dpc-4976	115	32	with	with	ADP
dpc-4976	115	33	moderate	moderate	ADJ
dpc-4976	115	34	-	-	PUNCT
dpc-4976	115	35	to	to	ADP
dpc-4976	115	36	-	-	PUNCT
dpc-4976	115	37	severe	severe	ADJ
dpc-4976	115	38	plaque	plaque	NOUN
dpc-4976	115	39	psoriasis	psoriasis	NOUN
dpc-4976	115	40	treated	treat	VERB
dpc-4976	115	41	across	across	ADP
dpc-4976	115	42	33	33	NUM
dpc-4976	115	43	italian	italian	ADJ
dpc-4976	115	44	dermatology	dermatology	NOUN
dpc-4976	115	45	clinics	clinic	NOUN
dpc-4976	115	46	.	.	PUNCT
dpc-4976	116	1	over	over	ADP
dpc-4976	116	2	36	36	NUM
dpc-4976	116	3	weeks	week	NOUN
dpc-4976	116	4	,	,	PUNCT
dpc-4976	116	5	bimekizumab	bimekizumab	X
dpc-4976	116	6	significantly	significantly	ADV
dpc-4976	116	7	reduced	reduce	VERB
dpc-4976	116	8	mean	mean	PROPN
dpc-4976	116	9	pasi	pasi	NOUN
dpc-4976	116	10	scores	score	NOUN
dpc-4976	116	11	,	,	PUNCT
dpc-4976	116	12	from	from	ADP
dpc-4976	116	13	16.6	16.6	NUM
dpc-4976	116	14	±	±	NUM
dpc-4976	116	15	9.4	9.4	NUM
dpc-4976	116	16	at	at	ADP
dpc-4976	116	17	baseline	baseline	NOUN
dpc-4976	116	18	to	to	ADP
dpc-4976	116	19	4.3	4.3	NUM
dpc-4976	116	20	±	±	NUM
dpc-4976	116	21	5.2	5.2	NUM
dpc-4976	116	22	at	at	ADP
dpc-4976	116	23	week	week	NOUN
dpc-4976	116	24	4	4	NUM
dpc-4976	116	25	and	and	CCONJ
dpc-4976	116	26	1.1	1.1	NUM
dpc-4976	116	27	±	±	NUM
dpc-4976	116	28	1.7	1.7	NUM
dpc-4976	116	29	at	at	ADP
dpc-4976	116	30	weeks	week	NOUN
dpc-4976	116	31	16	16	NUM
dpc-4976	116	32	and	and	CCONJ
dpc-4976	116	33	36	36	NUM
dpc-4976	116	34	(	(	PUNCT
dpc-4976	116	35	p	p	X
dpc-4976	116	36	<	<	X
dpc-4976	116	37	0.001	0.001	NUM
dpc-4976	116	38	)	)	PUNCT
dpc-4976	116	39	.	.	PUNCT
dpc-4976	117	1	by	by	ADP
dpc-4976	117	2	week	week	NOUN
dpc-4976	117	3	16	16	NUM
dpc-4976	117	4	,	,	PUNCT
dpc-4976	117	5	87.8	87.8	NUM
dpc-4976	117	6	%	%	NOUN
dpc-4976	117	7	,	,	PUNCT
dpc-4976	117	8	72.4	72.4	NUM
dpc-4976	117	9	%	%	NOUN
dpc-4976	117	10	,	,	PUNCT
dpc-4976	117	11	and	and	CCONJ
dpc-4976	117	12	53.1	53.1	NUM
dpc-4976	117	13	%	%	NOUN
dpc-4976	117	14	of	of	ADP
dpc-4976	117	15	patients	patient	NOUN
dpc-4976	117	16	achieved	achieve	VERB
dpc-4976	117	17	pasi	pasi	NOUN
dpc-4976	117	18	75	75	NUM
dpc-4976	117	19	,	,	PUNCT
dpc-4976	117	20	pasi	pasi	NOUN
dpc-4976	117	21	90	90	NUM
dpc-4976	117	22	,	,	PUNCT
dpc-4976	117	23	and	and	CCONJ
dpc-4976	117	24	pasi	pasi	NOUN
dpc-4976	117	25	100	100	NUM
dpc-4976	117	26	,	,	PUNCT
dpc-4976	117	27	respectively	respectively	ADV
dpc-4976	117	28	,	,	PUNCT
dpc-4976	117	29	with	with	ADP
dpc-4976	117	30	sustained	sustained	ADJ
dpc-4976	117	31	results	result	NOUN
dpc-4976	117	32	through	through	ADP
dpc-4976	117	33	week	week	NOUN
dpc-4976	117	34	36	36	NUM
dpc-4976	117	35	.	.	PUNCT
dpc-4976	118	1	clearance	clearance	NOUN
dpc-4976	118	2	of	of	ADP
dpc-4976	118	3	difficult	difficult	ADJ
dpc-4976	118	4	-	-	PUNCT
dpc-4976	118	5	to	to	ADP
dpc-4976	118	6	-	-	PUNCT
dpc-4976	118	7	treat	treat	NOUN
dpc-4976	118	8	areas	area	NOUN
dpc-4976	118	9	,	,	PUNCT
dpc-4976	118	10	including	include	VERB
dpc-4976	118	11	scalp	scalp	NOUN
dpc-4976	118	12	,	,	PUNCT
dpc-4976	118	13	genital	genital	ADJ
dpc-4976	118	14	,	,	PUNCT
dpc-4976	118	15	palmoplantar	palmoplantar	NOUN
dpc-4976	118	16	,	,	PUNCT
dpc-4976	118	17	and	and	CCONJ
dpc-4976	118	18	nail	nail	NOUN
dpc-4976	118	19	psoriasis	psoriasis	NOUN
dpc-4976	118	20	,	,	PUNCT
dpc-4976	118	21	was	be	AUX
dpc-4976	118	22	high	high	ADJ
dpc-4976	118	23	,	,	PUNCT
dpc-4976	118	24	with	with	ADP
dpc-4976	118	25	99	99	NUM
dpc-4976	118	26	%	%	NOUN
dpc-4976	118	27	achieving	achieve	VERB
dpc-4976	118	28	genital	genital	ADJ
dpc-4976	118	29	clearance	clearance	NOUN
dpc-4976	118	30	by	by	ADP
dpc-4976	118	31	week	week	NOUN
dpc-4976	118	32	36	36	NUM
dpc-4976	118	33	.	.	PUNCT
dpc-4976	119	1	the	the	DET
dpc-4976	119	2	treatment	treatment	NOUN
dpc-4976	119	3	was	be	AUX
dpc-4976	119	4	well	well	ADV
dpc-4976	119	5	tolerated	tolerate	VERB
dpc-4976	119	6	,	,	PUNCT
dpc-4976	119	7	with	with	ADP
dpc-4976	119	8	only	only	ADJ
dpc-4976	119	9	mild	mild	ADJ
dpc-4976	119	10	adverse	adverse	ADJ
dpc-4976	119	11	events	event	NOUN
dpc-4976	119	12	(	(	PUNCT
dpc-4976	119	13	5.1	5.1	NUM
dpc-4976	119	14	%	%	NOUN
dpc-4976	119	15	)	)	PUNCT
dpc-4976	119	16	,	,	PUNCT
dpc-4976	119	17	including	include	VERB
dpc-4976	119	18	eczema	eczema	NOUN
dpc-4976	119	19	and	and	CCONJ
dpc-4976	119	20	oral	oral	ADJ
dpc-4976	119	21	candidiasis	candidiasis	NOUN
dpc-4976	119	22	,	,	PUNCT
dpc-4976	119	23	managed	manage	VERB
dpc-4976	119	24	without	without	ADP
dpc-4976	119	25	discontinuation	discontinuation	NOUN
dpc-4976	119	26	[	[	X
dpc-4976	119	27	16	16	NUM
dpc-4976	119	28	]	]	PUNCT
dpc-4976	119	29	.	.	PUNCT
dpc-4976	120	1	moreover	moreover	ADV
dpc-4976	120	2	,	,	PUNCT
dpc-4976	120	3	the	the	DET
dpc-4976	120	4	data	data	NOUN
dpc-4976	120	5	’s	’s	PART
dpc-4976	120	6	consistency	consistency	NOUN
dpc-4976	120	7	across	across	ADP
dpc-4976	120	8	different	different	ADJ
dpc-4976	120	9	follow	follow	NOUN
dpc-4976	120	10	-	-	PUNCT
dpc-4976	120	11	up	up	ADP
dpc-4976	120	12	periods	period	NOUN
dpc-4976	120	13	reinforces	reinforce	VERB
dpc-4976	120	14	the	the	DET
dpc-4976	120	15	reliability	reliability	NOUN
dpc-4976	120	16	of	of	ADP
dpc-4976	120	17	bimekizumab	bimekizumab	NOUN
dpc-4976	120	18	a	a	DET
dpc-4976	120	19	real	real	ADJ
dpc-4976	120	20	-	-	PUNCT
dpc-4976	120	21	world	world	NOUN
dpc-4976	120	22	study	study	NOUN
dpc-4976	120	23	by	by	ADP
dpc-4976	120	24	gargiulo	gargiulo	NOUN
dpc-4976	120	25	et	et	PROPN
dpc-4976	120	26	al	al	PROPN
dpc-4976	120	27	.	.	PROPN
dpc-4976	120	28	included	include	VERB
dpc-4976	120	29	237	237	NUM
dpc-4976	120	30	patients	patient	NOUN
dpc-4976	120	31	to	to	PART
dpc-4976	120	32	assess	assess	VERB
dpc-4976	120	33	bimekizumab	bimekizumab	PROPN
dpc-4976	120	34	’s	’s	PART
dpc-4976	120	35	efficacy	efficacy	NOUN
dpc-4976	120	36	and	and	CCONJ
dpc-4976	120	37	safety	safety	NOUN
dpc-4976	120	38	over	over	ADP
dpc-4976	120	39	16	16	NUM
dpc-4976	120	40	weeks	week	NOUN
dpc-4976	120	41	.	.	PUNCT
dpc-4976	121	1	at	at	ADP
dpc-4976	121	2	16	16	NUM
dpc-4976	121	3	weeks	week	NOUN
dpc-4976	121	4	,	,	PUNCT
dpc-4976	121	5	75.4	75.4	NUM
dpc-4976	121	6	%	%	NOUN
dpc-4976	121	7	of	of	ADP
dpc-4976	121	8	patients	patient	NOUN
dpc-4976	121	9	achieved	achieve	VERB
dpc-4976	121	10	complete	complete	ADJ
dpc-4976	121	11	skin	skin	NOUN
dpc-4976	121	12	clearance	clearance	NOUN
dpc-4976	121	13	(	(	PUNCT
dpc-4976	121	14	pasi	pasi	NOUN
dpc-4976	121	15	100	100	NUM
dpc-4976	121	16	)	)	PUNCT
dpc-4976	121	17	,	,	PUNCT
dpc-4976	121	18	89.5	89.5	NUM
dpc-4976	121	19	%	%	NOUN
dpc-4976	121	20	achieved	achieve	VERB
dpc-4976	121	21	pasi	pasi	NOUN
dpc-4976	121	22	90	90	NUM
dpc-4976	121	23	,	,	PUNCT
dpc-4976	121	24	and	and	CCONJ
dpc-4976	121	25	94.7	94.7	NUM
dpc-4976	121	26	%	%	NOUN
dpc-4976	121	27	had	have	VERB
dpc-4976	121	28	a	a	DET
dpc-4976	121	29	pasi	pasi	NOUN
dpc-4976	121	30	score	score	NOUN
dpc-4976	121	31	of	of	ADP
dpc-4976	121	32	≤2	≤2	NOUN
dpc-4976	121	33	[	[	X
dpc-4976	121	34	7	7	NUM
dpc-4976	121	35	]	]	PUNCT
dpc-4976	121	36	.	.	PUNCT
dpc-4976	122	1	our	our	PRON
dpc-4976	122	2	cohort	cohort	NOUN
dpc-4976	122	3	of	of	ADP
dpc-4976	122	4	132	132	NUM
dpc-4976	122	5	patients	patient	NOUN
dpc-4976	122	6	showed	show	VERB
dpc-4976	122	7	a	a	DET
dpc-4976	122	8	similar	similar	ADJ
dpc-4976	122	9	reduction	reduction	NOUN
dpc-4976	122	10	in	in	ADP
dpc-4976	122	11	disease	disease	NOUN
dpc-4976	122	12	severity	severity	NOUN
dpc-4976	122	13	.	.	PUNCT
dpc-4976	123	1	the	the	DET
dpc-4976	123	2	mean	mean	ADJ
dpc-4976	123	3	pasi	pasi	PROPN
dpc-4976	123	4	score	score	NOUN
dpc-4976	123	5	decreased	decrease	VERB
dpc-4976	123	6	from	from	ADP
dpc-4976	123	7	14.41	14.41	NUM
dpc-4976	123	8	at	at	ADP
dpc-4976	123	9	baseline	baseline	NOUN
dpc-4976	123	10	to	to	ADP
dpc-4976	123	11	2.31	2.31	NUM
dpc-4976	123	12	at	at	ADP
dpc-4976	123	13	week	week	NOUN
dpc-4976	123	14	4	4	NUM
dpc-4976	123	15	,	,	PUNCT
dpc-4976	123	16	0.41	0.41	NUM
dpc-4976	123	17	at	at	ADP
dpc-4976	123	18	week	week	NOUN
dpc-4976	123	19	16	16	NUM
dpc-4976	123	20	,	,	PUNCT
dpc-4976	123	21	0.24	0.24	NUM
dpc-4976	123	22	at	at	ADP
dpc-4976	123	23	week	week	NOUN
dpc-4976	123	24	24	24	NUM
dpc-4976	123	25	,	,	PUNCT
dpc-4976	123	26	and	and	CCONJ
dpc-4976	123	27	0.18	0.18	NUM
dpc-4976	123	28	at	at	ADP
dpc-4976	123	29	week	week	NOUN
dpc-4976	123	30	52	52	NUM
dpc-4976	123	31	.	.	PUNCT
dpc-4976	124	1	a	a	DET
dpc-4976	124	2	subgroup	subgroup	NOUN
dpc-4976	124	3	of	of	ADP
dpc-4976	124	4	94	94	NUM
dpc-4976	124	5	patients	patient	NOUN
dpc-4976	124	6	followed	follow	VERB
dpc-4976	124	7	for	for	ADP
dpc-4976	124	8	24	24	NUM
dpc-4976	124	9	weeks	week	NOUN
dpc-4976	124	10	showed	show	VERB
dpc-4976	124	11	a	a	DET
dpc-4976	124	12	baseline	baseline	NOUN
dpc-4976	124	13	mean	mean	ADJ
dpc-4976	124	14	pasi	pasi	NOUN
dpc-4976	124	15	of	of	ADP
dpc-4976	124	16	14.76	14.76	NUM
dpc-4976	124	17	,	,	PUNCT
dpc-4976	124	18	decreasing	decrease	VERB
dpc-4976	124	19	to	to	ADP
dpc-4976	124	20	2.24	2.24	NUM
dpc-4976	124	21	at	at	ADP
dpc-4976	124	22	week	week	NOUN
dpc-4976	124	23	4	4	NUM
dpc-4976	124	24	,	,	PUNCT
dpc-4976	124	25	0.43	0.43	NUM
dpc-4976	124	26	at	at	ADP
dpc-4976	124	27	week	week	NOUN
dpc-4976	124	28	16	16	NUM
dpc-4976	124	29	,	,	PUNCT
dpc-4976	124	30	and	and	CCONJ
dpc-4976	124	31	0.24	0.24	NUM
dpc-4976	124	32	at	at	ADP
dpc-4976	124	33	week	week	NOUN
dpc-4976	124	34	24	24	NUM
dpc-4976	124	35	.	.	PUNCT
dpc-4976	125	1	these	these	DET
dpc-4976	125	2	results	result	NOUN
dpc-4976	125	3	underscore	underscore	VERB
dpc-4976	125	4	bimekizumab	bimekizumab	NOUN
dpc-4976	125	5	’s	’s	PART
dpc-4976	125	6	efficacy	efficacy	NOUN
dpc-4976	125	7	in	in	ADP
dpc-4976	125	8	reducing	reduce	VERB
dpc-4976	125	9	psoriasis	psoriasis	NOUN
dpc-4976	125	10	severity	severity	NOUN
dpc-4976	125	11	across	across	ADP
dpc-4976	125	12	different	different	ADJ
dpc-4976	125	13	cohorts	cohort	NOUN
dpc-4976	125	14	and	and	CCONJ
dpc-4976	125	15	timepoints	timepoint	NOUN
dpc-4976	125	16	,	,	PUNCT
dpc-4976	125	17	improving	improve	VERB
dpc-4976	125	18	patient	patient	ADJ
dpc-4976	125	19	quality	quality	NOUN
dpc-4976	125	20	of	of	ADP
dpc-4976	125	21	life	life	NOUN
dpc-4976	125	22	.	.	PUNCT
dpc-4976	126	1	these	these	DET
dpc-4976	126	2	findings	finding	NOUN
dpc-4976	126	3	are	be	AUX
dpc-4976	126	4	consistent	consistent	ADJ
dpc-4976	126	5	with	with	ADP
dpc-4976	126	6	prior	prior	ADJ
dpc-4976	126	7	studies	study	NOUN
dpc-4976	126	8	showing	show	VERB
dpc-4976	126	9	that	that	SCONJ
dpc-4976	126	10	rapid	rapid	ADJ
dpc-4976	126	11	and	and	CCONJ
dpc-4976	126	12	sustained	sustained	ADJ
dpc-4976	126	13	reductions	reduction	NOUN
dpc-4976	126	14	in	in	ADP
dpc-4976	126	15	pasi	pasi	NOUN
dpc-4976	126	16	scores	score	NOUN
dpc-4976	126	17	are	be	AUX
dpc-4976	126	18	indicative	indicative	ADJ
dpc-4976	126	19	of	of	ADP
dpc-4976	126	20	effective	effective	ADJ
dpc-4976	126	21	psoriasis	psoriasis	NOUN
dpc-4976	126	22	management	management	NOUN
dpc-4976	127	1	[	[	X
dpc-4976	127	2	14,15	14,15	NUM
dpc-4976	127	3	]	]	PUNCT
dpc-4976	127	4	.	.	PUNCT
dpc-4976	128	1	moreover	moreover	ADV
dpc-4976	128	2	,	,	PUNCT
dpc-4976	128	3	a	a	DET
dpc-4976	128	4	multicenter	multicenter	ADJ
dpc-4976	128	5	study	study	NOUN
dpc-4976	128	6	by	by	ADP
dpc-4976	128	7	gargiulo	gargiulo	NOUN
dpc-4976	128	8	et	et	PROPN
dpc-4976	128	9	al	al	PROPN
dpc-4976	128	10	.	.	PROPN
dpc-4976	128	11	demonstrated	demonstrate	VERB
dpc-4976	128	12	that	that	SCONJ
dpc-4976	128	13	75.4	75.4	NUM
dpc-4976	128	14	%	%	NOUN
dpc-4976	128	15	of	of	ADP
dpc-4976	128	16	patients	patient	NOUN
dpc-4976	128	17	achieved	achieve	VERB
dpc-4976	128	18	pasi	pasi	NOUN
dpc-4976	128	19	100	100	NUM
dpc-4976	128	20	by	by	ADP
dpc-4976	128	21	week	week	NOUN
dpc-4976	128	22	16	16	NUM
dpc-4976	128	23	,	,	PUNCT
dpc-4976	128	24	with	with	ADP
dpc-4976	128	25	89.5	89.5	NUM
dpc-4976	128	26	%	%	NOUN
dpc-4976	128	27	reaching	reach	VERB
dpc-4976	128	28	pasi	pasi	NOUN
dpc-4976	128	29	90	90	NUM
dpc-4976	128	30	and	and	CCONJ
dpc-4976	128	31	94.7	94.7	NUM
dpc-4976	128	32	%	%	NOUN
dpc-4976	128	33	achieving	achieve	VERB
dpc-4976	128	34	figure	figure	NOUN
dpc-4976	128	35	4	4	NUM
dpc-4976	128	36	.	.	PUNCT
dpc-4976	129	1	(	(	PUNCT
dpc-4976	129	2	a	a	X
dpc-4976	129	3	)	)	PUNCT
dpc-4976	129	4	mean	mean	PROPN
dpc-4976	129	5	pasi	pasi	NOUN
dpc-4976	129	6	head	head	NOUN
dpc-4976	129	7	subscore	subscore	ADV
dpc-4976	129	8	over	over	ADP
dpc-4976	129	9	time	time	NOUN
dpc-4976	129	10	.	.	PUNCT
dpc-4976	130	1	mean	mean	VERB
dpc-4976	130	2	pasi	pasi	NOUN
dpc-4976	130	3	subscore	subscore	ADV
dpc-4976	130	4	for	for	ADP
dpc-4976	130	5	the	the	DET
dpc-4976	130	6	head	head	NOUN
dpc-4976	130	7	region	region	NOUN
dpc-4976	130	8	over	over	ADP
dpc-4976	130	9	time	time	NOUN
dpc-4976	130	10	for	for	ADP
dpc-4976	130	11	all	all	DET
dpc-4976	130	12	enrolled	enrol	VERB
dpc-4976	130	13	patients	patient	NOUN
dpc-4976	130	14	.	.	PUNCT
dpc-4976	131	1	the	the	DET
dpc-4976	131	2	pasi	pasi	NOUN
dpc-4976	131	3	subscores	subscore	NOUN
dpc-4976	131	4	were	be	AUX
dpc-4976	131	5	recorded	record	VERB
dpc-4976	131	6	at	at	ADP
dpc-4976	131	7	baseline	baseline	NOUN
dpc-4976	131	8	,	,	PUNCT
dpc-4976	131	9	week	week	NOUN
dpc-4976	131	10	4	4	NUM
dpc-4976	131	11	(	(	PUNCT
dpc-4976	131	12	w4	w4	NOUN
dpc-4976	131	13	)	)	PUNCT
dpc-4976	131	14	,	,	PUNCT
dpc-4976	131	15	week	week	NOUN
dpc-4976	131	16	16	16	NUM
dpc-4976	131	17	(	(	PUNCT
dpc-4976	131	18	w16	w16	NOUN
dpc-4976	131	19	)	)	PUNCT
dpc-4976	131	20	,	,	PUNCT
dpc-4976	131	21	week	week	NOUN
dpc-4976	131	22	24	24	NUM
dpc-4976	131	23	(	(	PUNCT
dpc-4976	131	24	w24	w24	PROPN
dpc-4976	131	25	)	)	PUNCT
dpc-4976	131	26	,	,	PUNCT
dpc-4976	131	27	and	and	CCONJ
dpc-4976	131	28	week	week	NOUN
dpc-4976	131	29	52	52	NUM
dpc-4976	131	30	(	(	PUNCT
dpc-4976	131	31	w52	w52	NOUN
dpc-4976	131	32	)	)	PUNCT
dpc-4976	131	33	.	.	PUNCT
dpc-4976	132	1	(	(	PUNCT
dpc-4976	132	2	b	b	X
dpc-4976	132	3	)	)	PUNCT
dpc-4976	132	4	percentage	percentage	NOUN
dpc-4976	132	5	of	of	ADP
dpc-4976	132	6	patients	patient	NOUN
dpc-4976	132	7	achieving	achieve	VERB
dpc-4976	132	8	pasi	pasi	NOUN
dpc-4976	132	9	100	100	NUM
dpc-4976	132	10	subscore	subscore	ADJ
dpc-4976	132	11	for	for	ADP
dpc-4976	132	12	the	the	DET
dpc-4976	132	13	head	head	NOUN
dpc-4976	132	14	region	region	NOUN
dpc-4976	132	15	over	over	ADP
dpc-4976	132	16	time	time	NOUN
dpc-4976	132	17	.	.	PUNCT
dpc-4976	133	1	patients	patient	NOUN
dpc-4976	133	2	achieving	achieve	VERB
dpc-4976	133	3	a	a	DET
dpc-4976	133	4	pasi	pasi	NOUN
dpc-4976	133	5	100	100	NUM
dpc-4976	133	6	subscore	subscore	ADJ
dpc-4976	133	7	(	(	PUNCT
dpc-4976	133	8	complete	complete	ADJ
dpc-4976	133	9	clearance	clearance	NOUN
dpc-4976	133	10	of	of	ADP
dpc-4976	133	11	psoriasis	psoriasis	NOUN
dpc-4976	133	12	)	)	PUNCT
dpc-4976	133	13	for	for	ADP
dpc-4976	133	14	the	the	DET
dpc-4976	133	15	head	head	NOUN
dpc-4976	133	16	region	region	NOUN
dpc-4976	133	17	over	over	ADP
dpc-4976	133	18	time	time	NOUN
dpc-4976	133	19	for	for	ADP
dpc-4976	133	20	all	all	DET
dpc-4976	133	21	enrolled	enrol	VERB
dpc-4976	133	22	patients	patient	NOUN
dpc-4976	133	23	.	.	PUNCT
dpc-4976	134	1	the	the	DET
dpc-4976	134	2	percentages	percentage	NOUN
dpc-4976	134	3	are	be	AUX
dpc-4976	134	4	recorded	record	VERB
dpc-4976	134	5	at	at	ADP
dpc-4976	134	6	w4	w4	NOUN
dpc-4976	134	7	,	,	PUNCT
dpc-4976	134	8	w16	w16	PROPN
dpc-4976	134	9	,	,	PUNCT
dpc-4976	134	10	w24	w24	PROPN
dpc-4976	134	11	,	,	PUNCT
dpc-4976	134	12	and	and	CCONJ
dpc-4976	134	13	w52	w52	NOUN
dpc-4976	134	14	.	.	PUNCT
dpc-4976	135	1	original	original	ADJ
dpc-4976	135	2	article	article	NOUN
dpc-4976	135	3	|	|	ADV
dpc-4976	135	4	dermatol	dermatol	ADJ
dpc-4976	135	5	pract	pract	NOUN
dpc-4976	135	6	concept	concept	NOUN
dpc-4976	135	7	.	.	PUNCT
dpc-4976	136	1	2025;15(1):4976	2025;15(1):4976	NUM
dpc-4976	136	2	7	7	NUM
dpc-4976	136	3	figure	figure	NOUN
dpc-4976	136	4	5	5	NUM
dpc-4976	136	5	.	.	PUNCT
dpc-4976	137	1	(	(	PUNCT
dpc-4976	137	2	a	a	X
dpc-4976	137	3	)	)	PUNCT
dpc-4976	137	4	mean	mean	ADJ
dpc-4976	137	5	pasi	pasi	NOUN
dpc-4976	137	6	subscore	subscore	ADV
dpc-4976	137	7	for	for	ADP
dpc-4976	137	8	upper	upper	ADJ
dpc-4976	137	9	limb	limb	NOUN
dpc-4976	137	10	over	over	ADP
dpc-4976	137	11	time	time	NOUN
dpc-4976	137	12	for	for	ADP
dpc-4976	137	13	all	all	DET
dpc-4976	137	14	enrolled	enrol	VERB
dpc-4976	137	15	patients	patient	NOUN
dpc-4976	137	16	.	.	PUNCT
dpc-4976	138	1	the	the	DET
dpc-4976	138	2	scores	score	NOUN
dpc-4976	138	3	were	be	AUX
dpc-4976	138	4	recorded	record	VERB
dpc-4976	138	5	at	at	ADP
dpc-4976	138	6	baseline	baseline	NOUN
dpc-4976	138	7	,	,	PUNCT
dpc-4976	138	8	week	week	NOUN
dpc-4976	138	9	4	4	NUM
dpc-4976	138	10	(	(	PUNCT
dpc-4976	138	11	w4	w4	NOUN
dpc-4976	138	12	)	)	PUNCT
dpc-4976	138	13	,	,	PUNCT
dpc-4976	138	14	week	week	NOUN
dpc-4976	138	15	16	16	NUM
dpc-4976	138	16	(	(	PUNCT
dpc-4976	138	17	w16	w16	NOUN
dpc-4976	138	18	)	)	PUNCT
dpc-4976	138	19	,	,	PUNCT
dpc-4976	138	20	week	week	NOUN
dpc-4976	138	21	24	24	NUM
dpc-4976	138	22	(	(	PUNCT
dpc-4976	138	23	w24	w24	PROPN
dpc-4976	138	24	)	)	PUNCT
dpc-4976	138	25	,	,	PUNCT
dpc-4976	138	26	and	and	CCONJ
dpc-4976	138	27	week	week	NOUN
dpc-4976	138	28	52	52	NUM
dpc-4976	138	29	(	(	PUNCT
dpc-4976	138	30	w52	w52	NOUN
dpc-4976	138	31	)	)	PUNCT
dpc-4976	138	32	.	.	PUNCT
dpc-4976	139	1	(	(	PUNCT
dpc-4976	139	2	b	b	X
dpc-4976	139	3	)	)	PUNCT
dpc-4976	139	4	percentage	percentage	NOUN
dpc-4976	139	5	of	of	ADP
dpc-4976	139	6	patients	patient	NOUN
dpc-4976	139	7	achieving	achieve	VERB
dpc-4976	139	8	pasi	pasi	NOUN
dpc-4976	139	9	100	100	NUM
dpc-4976	139	10	subscore	subscore	ADV
dpc-4976	139	11	for	for	ADP
dpc-4976	139	12	upper	upper	ADJ
dpc-4976	139	13	limb	limb	NOUN
dpc-4976	139	14	over	over	ADP
dpc-4976	139	15	time	time	NOUN
dpc-4976	139	16	.	.	PUNCT
dpc-4976	140	1	patients	patient	NOUN
dpc-4976	140	2	achieving	achieve	VERB
dpc-4976	140	3	a	a	DET
dpc-4976	140	4	pasi	pasi	NOUN
dpc-4976	140	5	100	100	NUM
dpc-4976	140	6	subscore	subscore	ADJ
dpc-4976	140	7	(	(	PUNCT
dpc-4976	140	8	complete	complete	ADJ
dpc-4976	140	9	clearance	clearance	NOUN
dpc-4976	140	10	of	of	ADP
dpc-4976	140	11	psoriasis	psoriasis	NOUN
dpc-4976	140	12	)	)	PUNCT
dpc-4976	140	13	for	for	ADP
dpc-4976	140	14	the	the	DET
dpc-4976	140	15	upper	upper	ADJ
dpc-4976	140	16	limb	limb	NOUN
dpc-4976	140	17	over	over	ADP
dpc-4976	140	18	time	time	NOUN
dpc-4976	140	19	.	.	PUNCT
dpc-4976	141	1	the	the	DET
dpc-4976	141	2	percentages	percentage	NOUN
dpc-4976	141	3	were	be	AUX
dpc-4976	141	4	recorded	record	VERB
dpc-4976	141	5	at	at	ADP
dpc-4976	141	6	w4	w4	NOUN
dpc-4976	141	7	,	,	PUNCT
dpc-4976	141	8	w16	w16	PROPN
dpc-4976	141	9	,	,	PUNCT
dpc-4976	141	10	w24	w24	PROPN
dpc-4976	141	11	,	,	PUNCT
dpc-4976	141	12	and	and	CCONJ
dpc-4976	141	13	w52	w52	NOUN
dpc-4976	141	14	.	.	PUNCT
dpc-4976	142	1	as	as	ADP
dpc-4976	142	2	a	a	DET
dpc-4976	142	3	therapeutic	therapeutic	ADJ
dpc-4976	142	4	agent	agent	NOUN
dpc-4976	142	5	.	.	PUNCT
dpc-4976	143	1	the	the	DET
dpc-4976	143	2	continued	continue	VERB
dpc-4976	143	3	improvement	improvement	NOUN
dpc-4976	143	4	observed	observe	VERB
dpc-4976	143	5	up	up	ADP
dpc-4976	143	6	to	to	ADP
dpc-4976	143	7	week	week	NOUN
dpc-4976	143	8	52	52	NUM
dpc-4976	143	9	in	in	ADP
dpc-4976	143	10	a	a	DET
dpc-4976	143	11	subset	subset	NOUN
dpc-4976	143	12	of	of	ADP
dpc-4976	143	13	patients	patient	NOUN
dpc-4976	143	14	suggests	suggest	VERB
dpc-4976	143	15	that	that	SCONJ
dpc-4976	143	16	bimekizumab	bimekizumab	CCONJ
dpc-4976	143	17	not	not	PART
dpc-4976	143	18	only	only	ADV
dpc-4976	143	19	provides	provide	VERB
dpc-4976	143	20	immediate	immediate	ADJ
dpc-4976	143	21	benefits	benefit	NOUN
dpc-4976	143	22	but	but	CCONJ
dpc-4976	143	23	also	also	ADV
dpc-4976	143	24	maintains	maintain	VERB
dpc-4976	143	25	its	its	PRON
dpc-4976	143	26	efficacy	efficacy	NOUN
dpc-4976	143	27	over	over	ADP
dpc-4976	143	28	longer	long	ADJ
dpc-4976	143	29	treatment	treatment	NOUN
dpc-4976	143	30	durations	duration	NOUN
dpc-4976	143	31	.	.	PUNCT
dpc-4976	144	1	this	this	DET
dpc-4976	144	2	study	study	NOUN
dpc-4976	144	3	shows	show	VERB
dpc-4976	144	4	significant	significant	ADJ
dpc-4976	144	5	enhancements	enhancement	NOUN
dpc-4976	144	6	in	in	ADP
dpc-4976	144	7	pasi	pasi	NOUN
dpc-4976	144	8	scores	score	NOUN
dpc-4976	144	9	across	across	ADP
dpc-4976	144	10	different	different	ADJ
dpc-4976	144	11	body	body	NOUN
dpc-4976	144	12	parts	part	NOUN
dpc-4976	144	13	in	in	ADP
dpc-4976	144	14	patients	patient	NOUN
dpc-4976	144	15	who	who	PRON
dpc-4976	144	16	received	receive	VERB
dpc-4976	144	17	bimekizumab	bimekizumab	ADV
dpc-4976	144	18	.	.	PUNCT
dpc-4976	145	1	baseline	baseline	PROPN
dpc-4976	145	2	pasi	pasi	PROPN
dpc-4976	145	3	scores	score	NOUN
dpc-4976	145	4	for	for	ADP
dpc-4976	145	5	specific	specific	ADJ
dpc-4976	145	6	body	body	NOUN
dpc-4976	145	7	sites	site	NOUN
dpc-4976	145	8	were	be	AUX
dpc-4976	145	9	3.24	3.24	NUM
dpc-4976	145	10	for	for	ADP
dpc-4976	145	11	the	the	DET
dpc-4976	145	12	head	head	NOUN
dpc-4976	145	13	,	,	PUNCT
dpc-4976	145	14	8.49	8.49	NUM
dpc-4976	145	15	for	for	ADP
dpc-4976	145	16	upper	upper	ADJ
dpc-4976	145	17	limbs	limb	NOUN
dpc-4976	145	18	,	,	PUNCT
dpc-4976	145	19	8.35	8.35	NUM
dpc-4976	145	20	for	for	ADP
dpc-4976	145	21	the	the	DET
dpc-4976	145	22	trunk	trunk	NOUN
dpc-4976	145	23	,	,	PUNCT
dpc-4976	145	24	and	and	CCONJ
dpc-4976	145	25	8.61	8.61	NUM
dpc-4976	145	26	for	for	ADP
dpc-4976	145	27	lower	low	ADJ
dpc-4976	145	28	limbs	limb	NOUN
dpc-4976	145	29	,	,	PUNCT
dpc-4976	145	30	which	which	PRON
dpc-4976	145	31	dropped	drop	VERB
dpc-4976	145	32	significantly	significantly	ADV
dpc-4976	145	33	by	by	ADP
dpc-4976	145	34	week	week	NOUN
dpc-4976	145	35	24	24	NUM
dpc-4976	145	36	.	.	PUNCT
dpc-4976	146	1	by	by	ADP
dpc-4976	146	2	week	week	NOUN
dpc-4976	146	3	54	54	NUM
dpc-4976	146	4	,	,	PUNCT
dpc-4976	146	5	the	the	DET
dpc-4976	146	6	scores	score	NOUN
dpc-4976	146	7	further	far	ADV
dpc-4976	146	8	decreased	decrease	VERB
dpc-4976	146	9	.	.	PUNCT
dpc-4976	147	1	these	these	DET
dpc-4976	147	2	findings	finding	NOUN
dpc-4976	147	3	align	align	VERB
dpc-4976	147	4	well	well	ADV
dpc-4976	147	5	with	with	ADP
dpc-4976	147	6	other	other	ADJ
dpc-4976	147	7	real	real	ADJ
dpc-4976	147	8	-	-	PUNCT
dpc-4976	147	9	world	world	NOUN
dpc-4976	147	10	studies	study	NOUN
dpc-4976	147	11	evaluating	evaluate	VERB
dpc-4976	147	12	the	the	DET
dpc-4976	147	13	effectiveness	effectiveness	NOUN
dpc-4976	147	14	of	of	ADP
dpc-4976	147	15	bimekizumab	bimekizumab	PROPN
dpc-4976	147	16	.	.	PUNCT
dpc-4976	148	1	hagino	hagino	PROPN
dpc-4976	148	2	et	et	PROPN
dpc-4976	148	3	al	al	PROPN
dpc-4976	148	4	.	.	PROPN
dpc-4976	148	5	reported	report	VERB
dpc-4976	148	6	significant	significant	ADJ
dpc-4976	148	7	improvements	improvement	NOUN
dpc-4976	148	8	in	in	ADP
dpc-4976	148	9	pasi	pasi	NOUN
dpc-4976	148	10	scores	score	NOUN
dpc-4976	148	11	in	in	ADP
dpc-4976	148	12	a	a	DET
dpc-4976	148	13	cohort	cohort	NOUN
dpc-4976	148	14	of	of	ADP
dpc-4976	148	15	36	36	NUM
dpc-4976	148	16	japanese	japanese	ADJ
dpc-4976	148	17	patients	patient	NOUN
dpc-4976	148	18	,	,	PUNCT
dpc-4976	148	19	with	with	ADP
dpc-4976	148	20	median	median	ADJ
dpc-4976	148	21	pasi	pasi	NOUN
dpc-4976	148	22	reductions	reduction	NOUN
dpc-4976	148	23	of	of	ADP
dpc-4976	148	24	79.8	79.8	NUM
dpc-4976	148	25	%	%	NOUN
dpc-4976	148	26	at	at	ADP
dpc-4976	148	27	week	week	NOUN
dpc-4976	148	28	4	4	NUM
dpc-4976	148	29	and	and	CCONJ
dpc-4976	148	30	96.4	96.4	NUM
dpc-4976	148	31	%	%	NOUN
dpc-4976	148	32	achieving	achieve	VERB
dpc-4976	148	33	pasi	pasi	NOUN
dpc-4976	148	34	≤2	≤2	VERB
dpc-4976	148	35	by	by	ADP
dpc-4976	148	36	week	week	NOUN
dpc-4976	148	37	16	16	NUM
dpc-4976	149	1	[	[	X
dpc-4976	149	2	16	16	NUM
dpc-4976	149	3	]	]	PUNCT
dpc-4976	149	4	.	.	PUNCT
dpc-4976	150	1	the	the	DET
dpc-4976	150	2	pasi	pasi	PROPN
dpc-4976	150	3	assessment	assessment	NOUN
dpc-4976	150	4	on	on	ADP
dpc-4976	150	5	the	the	DET
dpc-4976	150	6	trunk	trunk	NOUN
dpc-4976	150	7	and	and	CCONJ
dpc-4976	150	8	upper	upper	ADJ
dpc-4976	150	9	and/or	and/or	CCONJ
dpc-4976	150	10	lower	low	ADJ
dpc-4976	150	11	extremities	extremity	NOUN
dpc-4976	150	12	promptly	promptly	ADV
dpc-4976	150	13	and	and	CCONJ
dpc-4976	150	14	significantly	significantly	ADV
dpc-4976	150	15	decreased	decrease	VERB
dpc-4976	150	16	at	at	ADP
dpc-4976	150	17	week	week	NOUN
dpc-4976	150	18	4	4	NUM
dpc-4976	150	19	by	by	ADP
dpc-4976	150	20	a	a	DET
dpc-4976	150	21	median	median	ADJ
dpc-4976	150	22	86.7	86.7	NUM
dpc-4976	150	23	%	%	NOUN
dpc-4976	150	24	,	,	PUNCT
dpc-4976	150	25	80.0	80.0	NUM
dpc-4976	150	26	%	%	NOUN
dpc-4976	150	27	,	,	PUNCT
dpc-4976	150	28	or	or	CCONJ
dpc-4976	150	29	66.7	66.7	NUM
dpc-4976	150	30	%	%	NOUN
dpc-4976	150	31	from	from	ADP
dpc-4976	150	32	baseline	baseline	NOUN
dpc-4976	150	33	,	,	PUNCT
dpc-4976	150	34	respectively	respectively	ADV
dpc-4976	150	35	,	,	PUNCT
dpc-4976	150	36	and	and	CCONJ
dpc-4976	150	37	then	then	ADV
dpc-4976	150	38	stabilized	stabilize	VERB
dpc-4976	150	39	.	.	PUNCT
dpc-4976	151	1	the	the	DET
dpc-4976	151	2	pasi	pasi	NOUN
dpc-4976	151	3	on	on	ADP
dpc-4976	151	4	the	the	DET
dpc-4976	151	5	scalp	scalp	NOUN
dpc-4976	151	6	and	and	CCONJ
dpc-4976	151	7	neck	neck	NOUN
dpc-4976	151	8	seemed	seem	VERB
dpc-4976	151	9	to	to	PART
dpc-4976	151	10	diminish	diminish	VERB
dpc-4976	151	11	at	at	ADP
dpc-4976	151	12	the	the	DET
dpc-4976	151	13	end	end	NOUN
dpc-4976	151	14	of	of	ADP
dpc-4976	151	15	the	the	DET
dpc-4976	151	16	fourth	fourth	ADJ
dpc-4976	151	17	week	week	NOUN
dpc-4976	151	18	by	by	ADP
dpc-4976	151	19	a	a	DET
dpc-4976	151	20	median	median	ADJ
dpc-4976	151	21	73.2	73.2	NUM
dpc-4976	151	22	%	%	NOUN
dpc-4976	151	23	from	from	ADP
dpc-4976	151	24	the	the	DET
dpc-4976	151	25	initial	initial	ADJ
dpc-4976	151	26	level	level	NOUN
dpc-4976	151	27	.	.	PUNCT
dpc-4976	152	1	these	these	DET
dpc-4976	152	2	results	result	NOUN
dpc-4976	152	3	further	far	ADV
dpc-4976	152	4	support	support	VERB
dpc-4976	152	5	the	the	DET
dpc-4976	152	6	effectiveness	effectiveness	NOUN
dpc-4976	152	7	of	of	ADP
dpc-4976	152	8	bimekizumab	bimekizumab	NOUN
dpc-4976	152	9	across	across	ADP
dpc-4976	152	10	different	different	ADJ
dpc-4976	152	11	patient	patient	ADJ
dpc-4976	152	12	populations	population	NOUN
dpc-4976	152	13	and	and	CCONJ
dpc-4976	152	14	geographical	geographical	ADJ
dpc-4976	152	15	regions	region	NOUN
dpc-4976	152	16	[	[	X
dpc-4976	152	17	17	17	NUM
dpc-4976	152	18	]	]	PUNCT
dpc-4976	152	19	.	.	PUNCT
dpc-4976	153	1	moreover	moreover	ADV
dpc-4976	153	2	,	,	PUNCT
dpc-4976	153	3	orsini	orsini	PROPN
dpc-4976	153	4	et	et	PROPN
dpc-4976	153	5	al	al	PROPN
dpc-4976	153	6	.	.	PROPN
dpc-4976	153	7	reported	report	VERB
dpc-4976	153	8	comparable	comparable	ADJ
dpc-4976	153	9	findings	finding	NOUN
dpc-4976	153	10	in	in	ADP
dpc-4976	153	11	their	their	PRON
dpc-4976	153	12	study	study	NOUN
dpc-4976	153	13	focused	focus	VERB
dpc-4976	153	14	on	on	ADP
dpc-4976	153	15	genital	genital	ADJ
dpc-4976	153	16	psoriasis	psoriasis	NOUN
dpc-4976	153	17	.	.	PUNCT
dpc-4976	154	1	their	their	PRON
dpc-4976	154	2	16	16	NUM
dpc-4976	154	3	-	-	PUNCT
dpc-4976	154	4	week	week	NOUN
dpc-4976	154	5	multicenter	multicenter	NOUN
dpc-4976	154	6	real	real	ADJ
dpc-4976	154	7	-	-	PUNCT
dpc-4976	154	8	world	world	NOUN
dpc-4976	154	9	study	study	NOUN
dpc-4976	154	10	found	find	VERB
dpc-4976	154	11	that	that	SCONJ
dpc-4976	154	12	98.4	98.4	NUM
dpc-4976	154	13	%	%	NOUN
dpc-4976	154	14	of	of	ADP
dpc-4976	154	15	patients	patient	NOUN
dpc-4976	154	16	achieved	achieve	VERB
dpc-4976	154	17	a	a	DET
dpc-4976	154	18	clear	clear	ADJ
dpc-4976	154	19	spga	spga	NOUN
dpc-4976	154	20	-	-	PUNCT
dpc-4976	154	21	g	g	NOUN
dpc-4976	154	22	score	score	NOUN
dpc-4976	154	23	,	,	PUNCT
dpc-4976	154	24	with	with	ADP
dpc-4976	154	25	significant	significant	ADJ
dpc-4976	154	26	improvements	improvement	NOUN
dpc-4976	154	27	in	in	ADP
dpc-4976	154	28	pasi	pasi	NOUN
dpc-4976	154	29	scores	score	NOUN
dpc-4976	154	30	and	and	CCONJ
dpc-4976	154	31	dermatology	dermatology	NOUN
dpc-4976	154	32	life	life	NOUN
dpc-4976	154	33	quality	quality	NOUN
dpc-4976	154	34	index	index	NOUN
dpc-4976	154	35	(	(	PUNCT
dpc-4976	154	36	dlqi	dlqi	ADJ
dpc-4976	154	37	)	)	PUNCT
dpc-4976	154	38	scores	score	NOUN
dpc-4976	154	39	,	,	PUNCT
dpc-4976	154	40	reinforcing	reinforce	VERB
dpc-4976	154	41	the	the	DET
dpc-4976	154	42	treatment	treatment	NOUN
dpc-4976	154	43	’s	’s	PART
dpc-4976	154	44	effectiveness	effectiveness	NOUN
dpc-4976	154	45	in	in	ADP
dpc-4976	154	46	challenging	challenge	VERB
dpc-4976	154	47	-	-	PUNCT
dpc-4976	154	48	to	to	ADP
dpc-4976	154	49	-	-	PUNCT
dpc-4976	154	50	treat	treat	NOUN
dpc-4976	154	51	areas	area	NOUN
dpc-4976	154	52	[	[	X
dpc-4976	154	53	18	18	NUM
dpc-4976	154	54	]	]	PUNCT
dpc-4976	154	55	.	.	PUNCT
dpc-4976	155	1	this	this	DET
dpc-4976	155	2	study	study	NOUN
dpc-4976	155	3	shows	show	VERB
dpc-4976	155	4	significant	significant	ADJ
dpc-4976	155	5	improvements	improvement	NOUN
dpc-4976	155	6	in	in	ADP
dpc-4976	155	7	pasi	pasi	NOUN
dpc-4976	155	8	subscores	subscore	NOUN
dpc-4976	155	9	across	across	ADP
dpc-4976	155	10	different	different	ADJ
dpc-4976	155	11	body	body	NOUN
dpc-4976	155	12	areas	area	NOUN
dpc-4976	155	13	with	with	ADP
dpc-4976	155	14	bimekizumab	bimekizumab	NOUN
dpc-4976	155	15	treatment	treatment	NOUN
dpc-4976	155	16	.	.	PUNCT
dpc-4976	156	1	detailed	detailed	ADJ
dpc-4976	156	2	outcomes	outcome	NOUN
dpc-4976	156	3	indicate	indicate	VERB
dpc-4976	156	4	bimekizumab	bimekizumab	NOUN
dpc-4976	156	5	effectiveness	effectiveness	NOUN
dpc-4976	156	6	in	in	ADP
dpc-4976	156	7	attaining	attain	VERB
dpc-4976	156	8	and	and	CCONJ
dpc-4976	156	9	sustaining	sustain	VERB
dpc-4976	156	10	skin	skin	NOUN
dpc-4976	156	11	clearance	clearance	NOUN
dpc-4976	156	12	.	.	PUNCT
dpc-4976	157	1	mean	mean	VERB
dpc-4976	157	2	pasi	pasi	NOUN
dpc-4976	157	3	subscores	subscore	NOUN
dpc-4976	157	4	for	for	ADP
dpc-4976	157	5	the	the	DET
dpc-4976	157	6	head	head	NOUN
dpc-4976	157	7	area	area	NOUN
dpc-4976	157	8	reduced	reduce	VERB
dpc-4976	157	9	from	from	ADP
dpc-4976	157	10	3.24	3.24	NUM
dpc-4976	157	11	at	at	ADP
dpc-4976	157	12	baseline	baseline	NOUN
dpc-4976	157	13	to	to	ADP
dpc-4976	157	14	0.13	0.13	NUM
dpc-4976	157	15	at	at	ADP
dpc-4976	157	16	week	week	NOUN
dpc-4976	157	17	54	54	NUM
dpc-4976	157	18	,	,	PUNCT
dpc-4976	157	19	with	with	ADP
dpc-4976	157	20	increasing	increase	VERB
dpc-4976	157	21	percentage	percentage	NOUN
dpc-4976	157	22	of	of	ADP
dpc-4976	157	23	patients	patient	NOUN
dpc-4976	157	24	achieving	achieve	VERB
dpc-4976	157	25	pasi	pasi	NOUN
dpc-4976	157	26	100	100	NUM
dpc-4976	157	27	over	over	ADP
dpc-4976	157	28	time	time	NOUN
dpc-4976	157	29	.	.	PUNCT
dpc-4976	158	1	patients	patient	NOUN
dpc-4976	158	2	with	with	ADP
dpc-4976	158	3	24	24	NUM
dpc-4976	158	4	-	-	PUNCT
dpc-4976	158	5	week	week	NOUN
dpc-4976	158	6	follow	follow	NOUN
dpc-4976	158	7	-	-	PUNCT
dpc-4976	158	8	up	up	NOUN
dpc-4976	158	9	showed	show	VERB
dpc-4976	158	10	a	a	DET
dpc-4976	158	11	decrease	decrease	NOUN
dpc-4976	158	12	in	in	ADP
dpc-4976	158	13	mean	mean	ADJ
dpc-4976	158	14	pasi	pasi	NOUN
dpc-4976	158	15	subscores	subscore	NOUN
dpc-4976	158	16	for	for	ADP
dpc-4976	158	17	the	the	DET
dpc-4976	158	18	head	head	NOUN
dpc-4976	158	19	and	and	CCONJ
dpc-4976	158	20	improved	improve	VERB
dpc-4976	158	21	percentage	percentage	NOUN
dpc-4976	158	22	of	of	ADP
dpc-4976	158	23	achieving	achieve	VERB
dpc-4976	158	24	pasi	pasi	NOUN
dpc-4976	158	25	100	100	NUM
dpc-4976	158	26	.	.	PUNCT
dpc-4976	159	1	a	a	DET
dpc-4976	159	2	shorter	short	ADJ
dpc-4976	159	3	time	time	NOUN
dpc-4976	159	4	from	from	ADP
dpc-4976	159	5	diagnosis	diagnosis	NOUN
dpc-4976	159	6	to	to	ADP
dpc-4976	159	7	bimekizumab	bimekizumab	NOUN
dpc-4976	159	8	treatment	treatment	NOUN
dpc-4976	159	9	initiation	initiation	NOUN
dpc-4976	159	10	and	and	CCONJ
dpc-4976	159	11	older	old	ADJ
dpc-4976	159	12	age	age	NOUN
dpc-4976	159	13	were	be	AUX
dpc-4976	159	14	linked	link	VERB
dpc-4976	159	15	to	to	ADP
dpc-4976	159	16	higher	high	ADJ
dpc-4976	159	17	chances	chance	NOUN
dpc-4976	159	18	of	of	ADP
dpc-4976	159	19	complete	complete	ADJ
dpc-4976	159	20	response	response	NOUN
dpc-4976	159	21	in	in	ADP
dpc-4976	159	22	head	head	NOUN
dpc-4976	159	23	pasi	pasi	NOUN
dpc-4976	159	24	subscore	subscore	ADV
dpc-4976	159	25	by	by	ADP
dpc-4976	159	26	week	week	NOUN
dpc-4976	159	27	16	16	NUM
dpc-4976	159	28	.	.	PUNCT
dpc-4976	160	1	the	the	DET
dpc-4976	160	2	mean	mean	ADJ
dpc-4976	160	3	pasi	pasi	NOUN
dpc-4976	160	4	subscores	subscore	NOUN
dpc-4976	160	5	for	for	ADP
dpc-4976	160	6	upper	upper	ADJ
dpc-4976	160	7	limbs	limb	NOUN
dpc-4976	160	8	decreased	decrease	VERB
dpc-4976	160	9	over	over	ADP
dpc-4976	160	10	time	time	NOUN
dpc-4976	160	11	,	,	PUNCT
dpc-4976	160	12	with	with	ADP
dpc-4976	160	13	the	the	DET
dpc-4976	160	14	percentage	percentage	NOUN
dpc-4976	160	15	of	of	ADP
dpc-4976	160	16	patients	patient	NOUN
dpc-4976	160	17	achieving	achieve	VERB
dpc-4976	160	18	pasi	pasi	NOUN
dpc-4976	160	19	8	8	NUM
dpc-4976	160	20	original	original	ADJ
dpc-4976	160	21	article	article	NOUN
dpc-4976	160	22	|	|	ADV
dpc-4976	160	23	dermatol	dermatol	ADJ
dpc-4976	160	24	pract	pract	NOUN
dpc-4976	160	25	concept	concept	NOUN
dpc-4976	160	26	.	.	PUNCT
dpc-4976	161	1	2025;15(1):4976	2025;15(1):4976	NUM
dpc-4976	161	2	figure	figure	NOUN
dpc-4976	161	3	6	6	NUM
dpc-4976	161	4	.	.	PUNCT
dpc-4976	162	1	(	(	PUNCT
dpc-4976	162	2	a	a	X
dpc-4976	162	3	)	)	PUNCT
dpc-4976	162	4	mean	mean	ADJ
dpc-4976	162	5	pasi	pasi	NOUN
dpc-4976	162	6	subscore	subscore	ADJ
dpc-4976	162	7	for	for	ADP
dpc-4976	162	8	trunk	trunk	NOUN
dpc-4976	162	9	over	over	ADP
dpc-4976	162	10	time	time	NOUN
dpc-4976	162	11	for	for	ADP
dpc-4976	162	12	all	all	DET
dpc-4976	162	13	enrolled	enrol	VERB
dpc-4976	162	14	patients	patient	NOUN
dpc-4976	162	15	.	.	PUNCT
dpc-4976	163	1	the	the	DET
dpc-4976	163	2	scores	score	NOUN
dpc-4976	163	3	were	be	AUX
dpc-4976	163	4	recorded	record	VERB
dpc-4976	163	5	at	at	ADP
dpc-4976	163	6	baseline	baseline	NOUN
dpc-4976	163	7	,	,	PUNCT
dpc-4976	163	8	week	week	NOUN
dpc-4976	163	9	4	4	NUM
dpc-4976	163	10	(	(	PUNCT
dpc-4976	163	11	w4	w4	NOUN
dpc-4976	163	12	)	)	PUNCT
dpc-4976	163	13	,	,	PUNCT
dpc-4976	163	14	week	week	NOUN
dpc-4976	163	15	16	16	NUM
dpc-4976	163	16	(	(	PUNCT
dpc-4976	163	17	w16	w16	NOUN
dpc-4976	163	18	)	)	PUNCT
dpc-4976	163	19	,	,	PUNCT
dpc-4976	163	20	week	week	NOUN
dpc-4976	163	21	24	24	NUM
dpc-4976	163	22	(	(	PUNCT
dpc-4976	163	23	w24	w24	PROPN
dpc-4976	163	24	)	)	PUNCT
dpc-4976	163	25	,	,	PUNCT
dpc-4976	163	26	and	and	CCONJ
dpc-4976	163	27	week	week	NOUN
dpc-4976	163	28	52	52	NUM
dpc-4976	163	29	(	(	PUNCT
dpc-4976	163	30	w52	w52	NOUN
dpc-4976	163	31	)	)	PUNCT
dpc-4976	163	32	.	.	PUNCT
dpc-4976	164	1	(	(	PUNCT
dpc-4976	164	2	b	b	X
dpc-4976	164	3	)	)	PUNCT
dpc-4976	164	4	percentage	percentage	NOUN
dpc-4976	164	5	of	of	ADP
dpc-4976	164	6	patients	patient	NOUN
dpc-4976	164	7	achieving	achieve	VERB
dpc-4976	164	8	pasi	pasi	NOUN
dpc-4976	164	9	100	100	NUM
dpc-4976	164	10	subscore	subscore	ADJ
dpc-4976	164	11	for	for	ADP
dpc-4976	164	12	trunk	trunk	NOUN
dpc-4976	164	13	over	over	ADP
dpc-4976	164	14	time	time	NOUN
dpc-4976	164	15	.	.	PUNCT
dpc-4976	165	1	patients	patient	NOUN
dpc-4976	165	2	achieving	achieve	VERB
dpc-4976	165	3	a	a	DET
dpc-4976	165	4	pasi	pasi	NOUN
dpc-4976	165	5	100	100	NUM
dpc-4976	165	6	subscore	subscore	ADJ
dpc-4976	165	7	(	(	PUNCT
dpc-4976	165	8	complete	complete	ADJ
dpc-4976	165	9	clearance	clearance	NOUN
dpc-4976	165	10	of	of	ADP
dpc-4976	165	11	psoriasis	psoriasis	NOUN
dpc-4976	165	12	)	)	PUNCT
dpc-4976	165	13	for	for	ADP
dpc-4976	165	14	the	the	DET
dpc-4976	165	15	trunk	trunk	NOUN
dpc-4976	165	16	region	region	NOUN
dpc-4976	165	17	over	over	ADP
dpc-4976	165	18	time	time	NOUN
dpc-4976	165	19	.	.	PUNCT
dpc-4976	166	1	the	the	DET
dpc-4976	166	2	percentages	percentage	NOUN
dpc-4976	166	3	were	be	AUX
dpc-4976	166	4	recorded	record	VERB
dpc-4976	166	5	at	at	ADP
dpc-4976	166	6	w4	w4	NOUN
dpc-4976	166	7	,	,	PUNCT
dpc-4976	166	8	w16	w16	PROPN
dpc-4976	166	9	,	,	PUNCT
dpc-4976	166	10	w24	w24	PROPN
dpc-4976	166	11	,	,	PUNCT
dpc-4976	166	12	and	and	CCONJ
dpc-4976	166	13	w52	w52	NOUN
dpc-4976	166	14	.	.	PUNCT
dpc-4976	167	1	100	100	NUM
dpc-4976	167	2	increasing	increase	VERB
dpc-4976	167	3	.	.	PUNCT
dpc-4976	168	1	the	the	DET
dpc-4976	168	2	mean	mean	ADJ
dpc-4976	168	3	pasi	pasi	NOUN
dpc-4976	168	4	subscores	subscore	NOUN
dpc-4976	168	5	for	for	ADP
dpc-4976	168	6	patients	patient	NOUN
dpc-4976	168	7	with	with	ADP
dpc-4976	168	8	24	24	NUM
dpc-4976	168	9	-	-	PUNCT
dpc-4976	168	10	week	week	NOUN
dpc-4976	168	11	follow	follow	NOUN
dpc-4976	168	12	-	-	PUNCT
dpc-4976	168	13	up	up	NOUN
dpc-4976	168	14	also	also	ADV
dpc-4976	168	15	decreased	decrease	VERB
dpc-4976	168	16	,	,	PUNCT
dpc-4976	168	17	with	with	ADP
dpc-4976	168	18	an	an	DET
dpc-4976	168	19	increasing	increase	VERB
dpc-4976	168	20	percentage	percentage	NOUN
dpc-4976	168	21	of	of	ADP
dpc-4976	168	22	achieving	achieve	VERB
dpc-4976	168	23	pasi	pasi	NOUN
dpc-4976	168	24	100	100	NUM
dpc-4976	168	25	.	.	PUNCT
dpc-4976	169	1	these	these	DET
dpc-4976	169	2	changes	change	NOUN
dpc-4976	169	3	from	from	ADP
dpc-4976	169	4	baseline	baseline	NOUN
dpc-4976	169	5	were	be	AUX
dpc-4976	169	6	statistically	statistically	ADV
dpc-4976	169	7	significant	significant	ADJ
dpc-4976	169	8	.	.	PUNCT
dpc-4976	170	1	similarly	similarly	ADV
dpc-4976	170	2	,	,	PUNCT
dpc-4976	170	3	for	for	ADP
dpc-4976	170	4	trunk	trunk	NOUN
dpc-4976	170	5	area	area	NOUN
dpc-4976	170	6	,	,	PUNCT
dpc-4976	170	7	mean	mean	ADJ
dpc-4976	170	8	pasi	pasi	NOUN
dpc-4976	170	9	subscores	subscore	NOUN
dpc-4976	170	10	decreased	decrease	VERB
dpc-4976	170	11	,	,	PUNCT
dpc-4976	170	12	with	with	ADP
dpc-4976	170	13	an	an	DET
dpc-4976	170	14	increasing	increase	VERB
dpc-4976	170	15	percentage	percentage	NOUN
dpc-4976	170	16	of	of	ADP
dpc-4976	170	17	patients	patient	NOUN
dpc-4976	170	18	achieving	achieve	VERB
dpc-4976	170	19	pasi	pasi	NOUN
dpc-4976	170	20	100	100	NUM
dpc-4976	170	21	.	.	PUNCT
dpc-4976	171	1	patients	patient	NOUN
dpc-4976	171	2	with	with	ADP
dpc-4976	171	3	24	24	NUM
dpc-4976	171	4	-	-	PUNCT
dpc-4976	171	5	week	week	NOUN
dpc-4976	171	6	follow	follow	NOUN
dpc-4976	171	7	-	-	PUNCT
dpc-4976	171	8	up	up	NOUN
dpc-4976	171	9	showed	show	VERB
dpc-4976	171	10	similar	similar	ADJ
dpc-4976	171	11	trends	trend	NOUN
dpc-4976	171	12	in	in	ADP
dpc-4976	171	13	mean	mean	ADJ
dpc-4976	171	14	pasi	pasi	NOUN
dpc-4976	171	15	subscores	subscore	NOUN
dpc-4976	171	16	and	and	CCONJ
dpc-4976	171	17	achievement	achievement	NOUN
dpc-4976	171	18	of	of	ADP
dpc-4976	171	19	pasi	pasi	NOUN
dpc-4976	171	20	100	100	NUM
dpc-4976	171	21	.	.	PUNCT
dpc-4976	172	1	changes	change	NOUN
dpc-4976	172	2	from	from	ADP
dpc-4976	172	3	baseline	baseline	PROPN
dpc-4976	172	4	were	be	AUX
dpc-4976	172	5	statistically	statistically	ADV
dpc-4976	172	6	significant	significant	ADJ
dpc-4976	172	7	.	.	PUNCT
dpc-4976	173	1	the	the	DET
dpc-4976	173	2	mean	mean	ADJ
dpc-4976	173	3	pasi	pasi	NOUN
dpc-4976	173	4	subscores	subscore	NOUN
dpc-4976	173	5	for	for	ADP
dpc-4976	173	6	lower	low	ADJ
dpc-4976	173	7	limbs	limb	NOUN
dpc-4976	173	8	decreased	decrease	VERB
dpc-4976	173	9	significantly	significantly	ADV
dpc-4976	173	10	over	over	ADP
dpc-4976	173	11	time	time	NOUN
dpc-4976	173	12	in	in	ADP
dpc-4976	173	13	enrolled	enrol	VERB
dpc-4976	173	14	patients	patient	NOUN
dpc-4976	173	15	.	.	PUNCT
dpc-4976	174	1	patients	patient	NOUN
dpc-4976	174	2	achieved	achieve	VERB
dpc-4976	174	3	pasi	pasi	NOUN
dpc-4976	174	4	100	100	NUM
dpc-4976	174	5	at	at	ADP
dpc-4976	174	6	varying	vary	VERB
dpc-4976	174	7	rates	rate	NOUN
dpc-4976	174	8	throughout	throughout	ADP
dpc-4976	174	9	the	the	DET
dpc-4976	174	10	study	study	NOUN
dpc-4976	174	11	.	.	PUNCT
dpc-4976	175	1	for	for	ADP
dpc-4976	175	2	patients	patient	NOUN
dpc-4976	175	3	with	with	ADP
dpc-4976	175	4	a	a	DET
dpc-4976	175	5	24	24	NUM
dpc-4976	175	6	-	-	PUNCT
dpc-4976	175	7	week	week	NOUN
dpc-4976	175	8	follow	follow	NOUN
dpc-4976	175	9	-	-	PUNCT
dpc-4976	175	10	up	up	NOUN
dpc-4976	175	11	,	,	PUNCT
dpc-4976	175	12	pasi	pasi	NOUN
dpc-4976	175	13	subscores	subscore	NOUN
dpc-4976	175	14	decreased	decrease	VERB
dpc-4976	175	15	significantly	significantly	ADV
dpc-4976	175	16	as	as	ADV
dpc-4976	175	17	well	well	ADV
dpc-4976	175	18	.	.	PUNCT
dpc-4976	176	1	the	the	DET
dpc-4976	176	2	percentage	percentage	NOUN
dpc-4976	176	3	of	of	ADP
dpc-4976	176	4	these	these	DET
dpc-4976	176	5	patients	patient	NOUN
dpc-4976	176	6	achieving	achieve	VERB
dpc-4976	176	7	pasi	pasi	NOUN
dpc-4976	176	8	100	100	NUM
dpc-4976	176	9	also	also	ADV
dpc-4976	176	10	increased	increase	VERB
dpc-4976	176	11	over	over	ADP
dpc-4976	176	12	time	time	NOUN
dpc-4976	176	13	.	.	PUNCT
dpc-4976	177	1	statistical	statistical	ADJ
dpc-4976	177	2	analysis	analysis	NOUN
dpc-4976	177	3	showed	show	VERB
dpc-4976	177	4	significant	significant	ADJ
dpc-4976	177	5	changes	change	NOUN
dpc-4976	177	6	in	in	ADP
dpc-4976	177	7	pasi	pasi	NOUN
dpc-4976	177	8	subscores	subscore	NOUN
dpc-4976	177	9	from	from	ADP
dpc-4976	177	10	baseline	baseline	NOUN
dpc-4976	177	11	at	at	ADP
dpc-4976	177	12	each	each	DET
dpc-4976	177	13	timepoint	timepoint	NOUN
dpc-4976	177	14	.	.	PUNCT
dpc-4976	178	1	these	these	DET
dpc-4976	178	2	results	result	NOUN
dpc-4976	178	3	are	be	AUX
dpc-4976	178	4	consistent	consistent	ADJ
dpc-4976	178	5	with	with	ADP
dpc-4976	178	6	other	other	ADJ
dpc-4976	178	7	studies	study	NOUN
dpc-4976	178	8	on	on	ADP
dpc-4976	178	9	bimekizumab	bimekizumab	NOUN
dpc-4976	178	10	,	,	PUNCT
dpc-4976	178	11	such	such	ADJ
dpc-4976	178	12	as	as	ADP
dpc-4976	178	13	that	that	PRON
dpc-4976	178	14	by	by	ADP
dpc-4976	178	15	merola	merola	PROPN
dpc-4976	178	16	et	et	PROPN
dpc-4976	178	17	al	al	PROPN
dpc-4976	178	18	.	.	PROPN
dpc-4976	178	19	,	,	PUNCT
dpc-4976	178	20	which	which	PRON
dpc-4976	178	21	reported	report	VERB
dpc-4976	178	22	high	high	ADJ
dpc-4976	178	23	rates	rate	NOUN
dpc-4976	178	24	of	of	ADP
dpc-4976	178	25	complete	complete	ADJ
dpc-4976	178	26	clearance	clearance	NOUN
dpc-4976	178	27	in	in	ADP
dpc-4976	178	28	high	high	ADJ
dpc-4976	178	29	-	-	PUNCT
dpc-4976	178	30	impact	impact	NOUN
dpc-4976	178	31	areas	area	NOUN
dpc-4976	178	32	like	like	ADP
dpc-4976	178	33	the	the	DET
dpc-4976	178	34	scalp	scalp	NOUN
dpc-4976	178	35	,	,	PUNCT
dpc-4976	178	36	nails	nail	NOUN
dpc-4976	178	37	,	,	PUNCT
dpc-4976	178	38	and	and	CCONJ
dpc-4976	178	39	palms	palm	NOUN
dpc-4976	178	40	over	over	ADP
dpc-4976	178	41	two	two	NUM
dpc-4976	178	42	years	year	NOUN
dpc-4976	178	43	of	of	ADP
dpc-4976	178	44	treatment	treatment	NOUN
dpc-4976	178	45	.	.	PUNCT
dpc-4976	179	1	warren	warren	PROPN
dpc-4976	179	2	et	et	PROPN
dpc-4976	179	3	al	al	PROPN
dpc-4976	179	4	.	.	PROPN
dpc-4976	180	1	and	and	CCONJ
dpc-4976	180	2	strober	strober	ADV
dpc-4976	180	3	et	et	PROPN
dpc-4976	180	4	al	al	PROPN
dpc-4976	180	5	.	.	PROPN
dpc-4976	180	6	also	also	ADV
dpc-4976	180	7	highlighted	highlight	VERB
dpc-4976	180	8	the	the	DET
dpc-4976	180	9	long	long	ADJ
dpc-4976	180	10	-	-	PUNCT
dpc-4976	180	11	term	term	NOUN
dpc-4976	180	12	efficacy	efficacy	NOUN
dpc-4976	180	13	and	and	CCONJ
dpc-4976	180	14	sustained	sustain	VERB
dpc-4976	180	15	response	response	NOUN
dpc-4976	180	16	of	of	ADP
dpc-4976	180	17	bimekizumab	bimekizumab	NOUN
dpc-4976	180	18	,	,	PUNCT
dpc-4976	180	19	demonstrating	demonstrate	VERB
dpc-4976	180	20	that	that	SCONJ
dpc-4976	180	21	high	high	ADJ
dpc-4976	180	22	levels	level	NOUN
dpc-4976	180	23	of	of	ADP
dpc-4976	180	24	clinical	clinical	ADJ
dpc-4976	180	25	response	response	NOUN
dpc-4976	180	26	are	be	AUX
dpc-4976	180	27	maintained	maintain	VERB
dpc-4976	180	28	through	through	ADP
dpc-4976	180	29	three	three	NUM
dpc-4976	180	30	years	year	NOUN
dpc-4976	180	31	of	of	ADP
dpc-4976	180	32	treatment	treatment	NOUN
dpc-4976	180	33	[	[	X
dpc-4976	180	34	19–21	19–21	NUM
dpc-4976	180	35	]	]	PUNCT
dpc-4976	180	36	.	.	PUNCT
dpc-4976	181	1	the	the	DET
dpc-4976	181	2	study	study	NOUN
dpc-4976	181	3	showed	show	VERB
dpc-4976	181	4	that	that	SCONJ
dpc-4976	181	5	bimekizumab	bimekizumab	NOUN
dpc-4976	181	6	led	lead	VERB
dpc-4976	181	7	to	to	ADP
dpc-4976	181	8	significant	significant	ADJ
dpc-4976	181	9	improvements	improvement	NOUN
dpc-4976	181	10	in	in	ADP
dpc-4976	181	11	dlqi	dlqi	ADJ
dpc-4976	181	12	scores	score	NOUN
dpc-4976	181	13	for	for	ADP
dpc-4976	181	14	psoriasis	psoriasis	NOUN
dpc-4976	181	15	patients	patient	NOUN
dpc-4976	181	16	.	.	PUNCT
dpc-4976	182	1	the	the	DET
dpc-4976	182	2	mean	mean	ADJ
dpc-4976	182	3	dlqi	dlqi	PROPN
dpc-4976	182	4	score	score	NOUN
dpc-4976	182	5	decreased	decrease	VERB
dpc-4976	182	6	from	from	ADP
dpc-4976	182	7	13.57	13.57	NUM
dpc-4976	182	8	to	to	PART
dpc-4976	182	9	0.86	0.86	NUM
dpc-4976	182	10	by	by	ADP
dpc-4976	182	11	week	week	NOUN
dpc-4976	182	12	16	16	NUM
dpc-4976	182	13	for	for	ADP
dpc-4976	182	14	all	all	DET
dpc-4976	182	15	patients	patient	NOUN
dpc-4976	182	16	.	.	PUNCT
dpc-4976	183	1	in	in	ADP
dpc-4976	183	2	the	the	DET
dpc-4976	183	3	subgroup	subgroup	NOUN
dpc-4976	183	4	with	with	ADP
dpc-4976	183	5	a	a	DET
dpc-4976	183	6	24	24	NUM
dpc-4976	183	7	-	-	PUNCT
dpc-4976	183	8	week	week	NOUN
dpc-4976	183	9	follow	follow	NOUN
dpc-4976	183	10	-	-	PUNCT
dpc-4976	183	11	up	up	NOUN
dpc-4976	183	12	,	,	PUNCT
dpc-4976	183	13	the	the	DET
dpc-4976	183	14	mean	mean	ADJ
dpc-4976	183	15	dlqi	dlqi	ADJ
dpc-4976	183	16	score	score	NOUN
dpc-4976	183	17	decreased	decrease	VERB
dpc-4976	183	18	similarly	similarly	ADV
dpc-4976	183	19	.	.	PUNCT
dpc-4976	184	1	by	by	ADP
dpc-4976	184	2	week	week	NOUN
dpc-4976	184	3	16	16	NUM
dpc-4976	184	4	,	,	PUNCT
dpc-4976	184	5	74	74	NUM
dpc-4976	184	6	%	%	NOUN
dpc-4976	184	7	of	of	ADP
dpc-4976	184	8	these	these	DET
dpc-4976	184	9	patients	patient	NOUN
dpc-4976	184	10	achieved	achieve	VERB
dpc-4976	184	11	a	a	DET
dpc-4976	184	12	dlqi	dlqi	ADJ
dpc-4976	184	13	score	score	NOUN
dpc-4976	184	14	of	of	ADP
dpc-4976	184	15	0	0	NUM
dpc-4976	184	16	or	or	CCONJ
dpc-4976	184	17	1	1	NUM
dpc-4976	184	18	,	,	PUNCT
dpc-4976	184	19	indicating	indicate	VERB
dpc-4976	184	20	no	no	DET
dpc-4976	184	21	impact	impact	NOUN
dpc-4976	184	22	on	on	ADP
dpc-4976	184	23	their	their	PRON
dpc-4976	184	24	quality	quality	NOUN
dpc-4976	184	25	of	of	ADP
dpc-4976	184	26	life	life	NOUN
dpc-4976	184	27	;	;	PUNCT
dpc-4976	184	28	24	24	NUM
dpc-4976	184	29	%	%	NOUN
dpc-4976	184	30	did	do	AUX
dpc-4976	184	31	not	not	PART
dpc-4976	184	32	achieve	achieve	VERB
dpc-4976	184	33	this	this	DET
dpc-4976	184	34	score	score	NOUN
dpc-4976	184	35	,	,	PUNCT
dpc-4976	184	36	and	and	CCONJ
dpc-4976	184	37	2	2	NUM
dpc-4976	184	38	%	%	NOUN
dpc-4976	184	39	had	have	VERB
dpc-4976	184	40	missing	miss	VERB
dpc-4976	184	41	data	datum	NOUN
dpc-4976	184	42	.	.	PUNCT
dpc-4976	185	1	these	these	DET
dpc-4976	185	2	findings	finding	NOUN
dpc-4976	185	3	are	be	AUX
dpc-4976	185	4	consistent	consistent	ADJ
dpc-4976	185	5	with	with	ADP
dpc-4976	185	6	previous	previous	ADJ
dpc-4976	185	7	studies	study	NOUN
dpc-4976	185	8	evaluating	evaluate	VERB
dpc-4976	185	9	the	the	DET
dpc-4976	185	10	efficacy	efficacy	NOUN
dpc-4976	185	11	of	of	ADP
dpc-4976	185	12	bimekizumab	bimekizumab	NOUN
dpc-4976	185	13	in	in	ADP
dpc-4976	185	14	the	the	DET
dpc-4976	185	15	treatment	treatment	NOUN
dpc-4976	185	16	of	of	ADP
dpc-4976	185	17	moderate	moderate	ADJ
dpc-4976	185	18	-	-	PUNCT
dpc-4976	185	19	to	to	ADP
dpc-4976	185	20	-	-	PUNCT
dpc-4976	185	21	severe	severe	ADJ
dpc-4976	185	22	plaque	plaque	NOUN
dpc-4976	185	23	psoriasis	psoriasis	NOUN
dpc-4976	185	24	.	.	PUNCT
dpc-4976	186	1	strober	strober	ADV
dpc-4976	186	2	et	et	PROPN
dpc-4976	186	3	al	al	PROPN
dpc-4976	186	4	.	.	PROPN
dpc-4976	186	5	reported	report	VERB
dpc-4976	186	6	that	that	SCONJ
dpc-4976	186	7	among	among	ADP
dpc-4976	186	8	patients	patient	NOUN
dpc-4976	186	9	achieving	achieve	VERB
dpc-4976	186	10	a	a	DET
dpc-4976	186	11	pasi	pasi	NOUN
dpc-4976	186	12	100	100	NUM
dpc-4976	186	13	response	response	NOUN
dpc-4976	186	14	at	at	ADP
dpc-4976	186	15	week	week	NOUN
dpc-4976	186	16	16	16	NUM
dpc-4976	186	17	,	,	PUNCT
dpc-4976	186	18	76.3	76.3	NUM
dpc-4976	186	19	%	%	NOUN
dpc-4976	186	20	also	also	ADV
dpc-4976	186	21	achieved	achieve	VERB
dpc-4976	186	22	a	a	DET
dpc-4976	186	23	dlqi	dlqi	ADJ
dpc-4976	186	24	0/1	0/1	NUM
dpc-4976	186	25	response	response	NOUN
dpc-4976	186	26	,	,	PUNCT
dpc-4976	186	27	which	which	PRON
dpc-4976	186	28	increased	increase	VERB
dpc-4976	186	29	to	to	ADP
dpc-4976	186	30	89.0	89.0	NUM
dpc-4976	186	31	%	%	NOUN
dpc-4976	186	32	by	by	ADP
dpc-4976	186	33	the	the	DET
dpc-4976	186	34	end	end	NOUN
dpc-4976	186	35	of	of	ADP
dpc-4976	186	36	year	year	NOUN
dpc-4976	186	37	3	3	NUM
dpc-4976	186	38	of	of	ADP
dpc-4976	186	39	continuous	continuous	ADJ
dpc-4976	186	40	bimekizumab	bimekizumab	NOUN
dpc-4976	186	41	treatment	treatment	NOUN
dpc-4976	186	42	[	[	X
dpc-4976	186	43	21	21	NUM
dpc-4976	186	44	]	]	PUNCT
dpc-4976	186	45	.	.	PUNCT
dpc-4976	187	1	this	this	DET
dpc-4976	187	2	sustained	sustained	ADJ
dpc-4976	187	3	improvement	improvement	NOUN
dpc-4976	187	4	in	in	ADP
dpc-4976	187	5	quality	quality	NOUN
dpc-4976	187	6	of	of	ADP
dpc-4976	187	7	life	life	NOUN
dpc-4976	187	8	underscores	underscore	VERB
dpc-4976	187	9	the	the	DET
dpc-4976	187	10	long	long	ADJ
dpc-4976	187	11	-	-	PUNCT
dpc-4976	187	12	term	term	NOUN
dpc-4976	187	13	benefits	benefit	NOUN
dpc-4976	187	14	of	of	ADP
dpc-4976	187	15	bimekizumab	bimekizumab	NOUN
dpc-4976	187	16	beyond	beyond	ADP
dpc-4976	187	17	mere	mere	ADJ
dpc-4976	187	18	clinical	clinical	ADJ
dpc-4976	187	19	skin	skin	NOUN
dpc-4976	187	20	clearance	clearance	NOUN
dpc-4976	187	21	.	.	PUNCT
dpc-4976	188	1	comparative	comparative	ADJ
dpc-4976	188	2	studies	study	NOUN
dpc-4976	188	3	have	have	AUX
dpc-4976	188	4	shown	show	VERB
dpc-4976	188	5	that	that	SCONJ
dpc-4976	188	6	bimekizumab	bimekizumab	PROPN
dpc-4976	188	7	offers	offer	VERB
dpc-4976	188	8	superior	superior	ADJ
dpc-4976	188	9	efficacy	efficacy	NOUN
dpc-4976	188	10	over	over	ADP
dpc-4976	188	11	other	other	ADJ
dpc-4976	188	12	biologics	biologic	NOUN
dpc-4976	188	13	.	.	PUNCT
dpc-4976	189	1	in	in	ADP
dpc-4976	189	2	the	the	DET
dpc-4976	189	3	be	be	NOUN
dpc-4976	189	4	vivid	vivid	ADJ
dpc-4976	189	5	trial	trial	NOUN
dpc-4976	189	6	,	,	PUNCT
dpc-4976	189	7	bimekizumab	bimekizumab	PROPN
dpc-4976	189	8	demonstrated	demonstrate	VERB
dpc-4976	189	9	a	a	DET
dpc-4976	189	10	significantly	significantly	ADV
dpc-4976	189	11	higher	high	ADJ
dpc-4976	189	12	rate	rate	NOUN
dpc-4976	189	13	of	of	ADP
dpc-4976	189	14	pasi	pasi	NOUN
dpc-4976	189	15	90	90	NUM
dpc-4976	189	16	response	response	NOUN
dpc-4976	189	17	compared	compare	VERB
dpc-4976	189	18	to	to	ADP
dpc-4976	189	19	ustekinumab	ustekinumab	NOUN
dpc-4976	189	20	and	and	CCONJ
dpc-4976	189	21	placebo	placebo	NOUN
dpc-4976	189	22	at	at	ADP
dpc-4976	189	23	week	week	NOUN
dpc-4976	189	24	16	16	NUM
dpc-4976	189	25	,	,	PUNCT
dpc-4976	189	26	with	with	ADP
dpc-4976	189	27	corresponding	correspond	VERB
dpc-4976	189	28	improvements	improvement	NOUN
dpc-4976	189	29	in	in	ADP
dpc-4976	189	30	dlqi	dlqi	ADJ
dpc-4976	189	31	original	original	ADJ
dpc-4976	189	32	article	article	NOUN
dpc-4976	189	33	|	|	ADV
dpc-4976	189	34	dermatol	dermatol	ADJ
dpc-4976	189	35	pract	pract	NOUN
dpc-4976	189	36	concept	concept	NOUN
dpc-4976	189	37	.	.	PUNCT
dpc-4976	190	1	2025;15(1):4976	2025;15(1):4976	NUM
dpc-4976	190	2	9	9	NUM
dpc-4976	190	3	conclusion	conclusion	NOUN
dpc-4976	190	4	the	the	DET
dpc-4976	190	5	current	current	ADJ
dpc-4976	190	6	study	study	NOUN
dpc-4976	190	7	adds	add	VERB
dpc-4976	190	8	valuable	valuable	ADJ
dpc-4976	190	9	real	real	ADJ
dpc-4976	190	10	-	-	PUNCT
dpc-4976	190	11	world	world	NOUN
dpc-4976	190	12	evidence	evidence	NOUN
dpc-4976	190	13	to	to	ADP
dpc-4976	190	14	the	the	DET
dpc-4976	190	15	growing	grow	VERB
dpc-4976	190	16	body	body	NOUN
dpc-4976	190	17	of	of	ADP
dpc-4976	190	18	literature	literature	NOUN
dpc-4976	190	19	supporting	support	VERB
dpc-4976	190	20	the	the	DET
dpc-4976	190	21	use	use	NOUN
dpc-4976	190	22	of	of	ADP
dpc-4976	190	23	bimekizumab	bimekizumab	NOUN
dpc-4976	190	24	in	in	ADP
dpc-4976	190	25	psoriasis	psoriasis	NOUN
dpc-4976	190	26	management	management	NOUN
dpc-4976	190	27	.	.	PUNCT
dpc-4976	191	1	these	these	DET
dpc-4976	191	2	results	result	NOUN
dpc-4976	191	3	offer	offer	VERB
dpc-4976	191	4	promising	promise	VERB
dpc-4976	191	5	implications	implication	NOUN
dpc-4976	191	6	for	for	ADP
dpc-4976	191	7	clinical	clinical	ADJ
dpc-4976	191	8	practice	practice	NOUN
dpc-4976	191	9	,	,	PUNCT
dpc-4976	191	10	suggesting	suggest	VERB
dpc-4976	191	11	that	that	SCONJ
dpc-4976	191	12	bimekizumab	bimekizumab	NOUN
dpc-4976	191	13	can	can	AUX
dpc-4976	191	14	significantly	significantly	ADV
dpc-4976	191	15	enhance	enhance	VERB
dpc-4976	191	16	the	the	DET
dpc-4976	191	17	quality	quality	NOUN
dpc-4976	191	18	of	of	ADP
dpc-4976	191	19	life	life	NOUN
dpc-4976	191	20	of	of	ADP
dpc-4976	191	21	patients	patient	NOUN
dpc-4976	191	22	with	with	ADP
dpc-4976	191	23	moderate	moderate	ADJ
dpc-4976	191	24	-	-	PUNCT
dpc-4976	191	25	to	to	ADP
dpc-4976	191	26	-	-	PUNCT
dpc-4976	191	27	severe	severe	ADJ
dpc-4976	191	28	psoriasis	psoriasis	NOUN
dpc-4976	191	29	by	by	ADP
dpc-4976	191	30	providing	provide	VERB
dpc-4976	191	31	rapid	rapid	ADJ
dpc-4976	191	32	and	and	CCONJ
dpc-4976	191	33	sustained	sustained	ADJ
dpc-4976	191	34	improvements	improvement	NOUN
dpc-4976	191	35	in	in	ADP
dpc-4976	191	36	skin	skin	NOUN
dpc-4976	191	37	clearance	clearance	NOUN
dpc-4976	191	38	and	and	CCONJ
dpc-4976	191	39	overall	overall	ADJ
dpc-4976	191	40	well	well	ADV
dpc-4976	191	41	-	-	PUNCT
dpc-4976	191	42	being	being	NOUN
dpc-4976	191	43	.	.	PUNCT
dpc-4976	192	1	author	author	NOUN
dpc-4976	192	2	’s	’s	PART
dpc-4976	192	3	contribution	contribution	NOUN
dpc-4976	192	4	:	:	PUNCT
dpc-4976	192	5	ad	ad	NOUN
dpc-4976	192	6	,	,	PUNCT
dpc-4976	192	7	gp	gp	NOUN
dpc-4976	192	8	,	,	PUNCT
dpc-4976	192	9	agr	agr	ADV
dpc-4976	192	10	,	,	PUNCT
dpc-4976	192	11	nb	nb	PROPN
dpc-4976	192	12	conceptualized	conceptualize	VERB
dpc-4976	192	13	the	the	DET
dpc-4976	192	14	work	work	NOUN
dpc-4976	192	15	,	,	PUNCT
dpc-4976	192	16	ad	ad	NOUN
dpc-4976	192	17	,	,	PUNCT
dpc-4976	192	18	gp	gp	NOUN
dpc-4976	192	19	,	,	PUNCT
dpc-4976	192	20	agr	agr	X
dpc-4976	192	21	,	,	PUNCT
dpc-4976	192	22	nb	nb	PROPN
dpc-4976	192	23	,	,	PUNCT
dpc-4976	192	24	drafted	draft	VERB
dpc-4976	192	25	the	the	DET
dpc-4976	192	26	work	work	NOUN
dpc-4976	192	27	,	,	PUNCT
dpc-4976	192	28	ad	ad	NOUN
dpc-4976	192	29	,	,	PUNCT
dpc-4976	192	30	gp	gp	NOUN
dpc-4976	192	31	,	,	PUNCT
dpc-4976	192	32	agr	agr	NOUN
dpc-4976	192	33	,	,	PUNCT
dpc-4976	192	34	nb	nb	INTJ
dpc-4976	192	35	,	,	PUNCT
dpc-4976	192	36	and	and	CCONJ
dpc-4976	192	37	all	all	DET
dpc-4976	192	38	authors	author	NOUN
dpc-4976	192	39	critically	critically	ADV
dpc-4976	192	40	revised	revise	VERB
dpc-4976	192	41	and	and	CCONJ
dpc-4976	192	42	approved	approve	VERB
dpc-4976	192	43	the	the	DET
dpc-4976	192	44	final	final	ADJ
dpc-4976	192	45	version	version	NOUN
dpc-4976	192	46	.	.	PUNCT
dpc-4976	193	1	references	reference	NOUN
dpc-4976	193	2	1	1	NUM
dpc-4976	193	3	.	.	PUNCT
dpc-4976	193	4	parisi	parisi	PROPN
dpc-4976	193	5	r	r	PROPN
dpc-4976	193	6	,	,	PUNCT
dpc-4976	193	7	iskandar	iskandar	PROPN
dpc-4976	193	8	iyk	iyk	PROPN
dpc-4976	193	9	,	,	PUNCT
dpc-4976	193	10	kontopantelis	kontopantelis	PROPN
dpc-4976	193	11	e	e	PROPN
dpc-4976	193	12	,	,	PUNCT
dpc-4976	193	13	augustin	augustin	PROPN
dpc-4976	193	14	m	m	PROPN
dpc-4976	193	15	,	,	PUNCT
dpc-4976	193	16	griffiths	griffiths	PROPN
dpc-4976	193	17	cem	cem	PROPN
dpc-4976	193	18	,	,	PUNCT
dpc-4976	193	19	ashcroft	ashcroft	PROPN
dpc-4976	193	20	dm	dm	PROPN
dpc-4976	193	21	.	.	PUNCT
dpc-4976	193	22	national	national	ADJ
dpc-4976	193	23	,	,	PUNCT
dpc-4976	193	24	regional	regional	ADJ
dpc-4976	193	25	,	,	PUNCT
dpc-4976	193	26	and	and	CCONJ
dpc-4976	193	27	worldwide	worldwide	ADJ
dpc-4976	193	28	epidemiology	epidemiology	NOUN
dpc-4976	193	29	of	of	ADP
dpc-4976	193	30	psoriasis	psoriasis	NOUN
dpc-4976	193	31	:	:	PUNCT
dpc-4976	193	32	systematic	systematic	ADJ
dpc-4976	193	33	analysis	analysis	NOUN
dpc-4976	193	34	and	and	CCONJ
dpc-4976	193	35	modelling	model	VERB
dpc-4976	193	36	study	study	NOUN
dpc-4976	193	37	.	.	PUNCT
dpc-4976	194	1	bmj	bmj	PROPN
dpc-4976	194	2	.	.	PUNCT
dpc-4976	195	1	2020;369	2020;369	NUM
dpc-4976	195	2	.	.	PUNCT
dpc-4976	196	1	doi	doi	NOUN
dpc-4976	196	2	:	:	PUNCT
dpc-4976	196	3	10.1136	10.1136	NUM
dpc-4976	196	4	/	/	SYM
dpc-4976	196	5	bmj.m1590	bmj.m1590	NUM
dpc-4976	196	6	.	.	PUNCT
dpc-4976	197	1	scores	score	NOUN
dpc-4976	197	2	[	[	X
dpc-4976	197	3	22	22	NUM
dpc-4976	197	4	]	]	PUNCT
dpc-4976	197	5	.	.	PUNCT
dpc-4976	198	1	similarly	similarly	ADV
dpc-4976	198	2	,	,	PUNCT
dpc-4976	198	3	ruggiero	ruggiero	PROPN
dpc-4976	198	4	et	et	PROPN
dpc-4976	198	5	al	al	PROPN
dpc-4976	198	6	.	.	PROPN
dpc-4976	198	7	reported	report	VERB
dpc-4976	198	8	that	that	SCONJ
dpc-4976	198	9	bimekizumab	bimekizumab	NOUN
dpc-4976	198	10	treatment	treatment	NOUN
dpc-4976	198	11	resulted	result	VERB
dpc-4976	198	12	in	in	ADP
dpc-4976	198	13	a	a	DET
dpc-4976	198	14	91	91	NUM
dpc-4976	198	15	%	%	NOUN
dpc-4976	198	16	pasi	pasi	NOUN
dpc-4976	198	17	90	90	NUM
dpc-4976	198	18	response	response	NOUN
dpc-4976	198	19	rate	rate	NOUN
dpc-4976	198	20	at	at	ADP
dpc-4976	198	21	week	week	NOUN
dpc-4976	198	22	16	16	NUM
dpc-4976	198	23	,	,	PUNCT
dpc-4976	198	24	with	with	ADP
dpc-4976	198	25	significant	significant	ADJ
dpc-4976	198	26	improvements	improvement	NOUN
dpc-4976	198	27	in	in	ADP
dpc-4976	198	28	dlqi	dlqi	ADJ
dpc-4976	198	29	scores	score	NOUN
dpc-4976	198	30	[	[	X
dpc-4976	198	31	13	13	NUM
dpc-4976	198	32	]	]	PUNCT
dpc-4976	198	33	.	.	PUNCT
dpc-4976	199	1	the	the	DET
dpc-4976	199	2	data	datum	NOUN
dpc-4976	199	3	from	from	ADP
dpc-4976	199	4	sharma	sharma	PROPN
dpc-4976	199	5	et	et	PROPN
dpc-4976	199	6	al	al	PROPN
dpc-4976	199	7	.	.	PROPN
dpc-4976	199	8	corroborate	corroborate	VERB
dpc-4976	199	9	these	these	DET
dpc-4976	199	10	findings	finding	NOUN
dpc-4976	199	11	,	,	PUNCT
dpc-4976	199	12	showing	show	VERB
dpc-4976	199	13	that	that	SCONJ
dpc-4976	199	14	patients	patient	NOUN
dpc-4976	199	15	treated	treat	VERB
dpc-4976	199	16	with	with	ADP
dpc-4976	199	17	bimekizumab	bimekizumab	NOUN
dpc-4976	199	18	experienced	experienced	ADJ
dpc-4976	199	19	substantial	substantial	ADJ
dpc-4976	199	20	improvements	improvement	NOUN
dpc-4976	199	21	in	in	ADP
dpc-4976	199	22	both	both	PRON
dpc-4976	199	23	pasi	pasi	NOUN
dpc-4976	199	24	scores	score	NOUN
dpc-4976	199	25	and	and	CCONJ
dpc-4976	199	26	quality	quality	NOUN
dpc-4976	199	27	of	of	ADP
dpc-4976	199	28	life	life	NOUN
dpc-4976	199	29	measures	measure	NOUN
dpc-4976	199	30	,	,	PUNCT
dpc-4976	199	31	which	which	PRON
dpc-4976	199	32	were	be	AUX
dpc-4976	199	33	sustained	sustain	VERB
dpc-4976	199	34	over	over	ADP
dpc-4976	199	35	long	long	ADJ
dpc-4976	199	36	-	-	PUNCT
dpc-4976	199	37	term	term	NOUN
dpc-4976	199	38	treatment	treatment	NOUN
dpc-4976	199	39	periods	period	NOUN
dpc-4976	199	40	[	[	X
dpc-4976	199	41	23	23	NUM
dpc-4976	199	42	]	]	PUNCT
dpc-4976	199	43	.	.	PUNCT
dpc-4976	200	1	limitations	limitation	NOUN
dpc-4976	200	2	while	while	SCONJ
dpc-4976	200	3	the	the	DET
dpc-4976	200	4	findings	finding	NOUN
dpc-4976	200	5	provide	provide	VERB
dpc-4976	200	6	compelling	compelling	ADJ
dpc-4976	200	7	evidence	evidence	NOUN
dpc-4976	200	8	of	of	ADP
dpc-4976	200	9	the	the	DET
dpc-4976	200	10	efficacy	efficacy	NOUN
dpc-4976	200	11	of	of	ADP
dpc-4976	200	12	bimekizumab	bimekizumab	NOUN
dpc-4976	200	13	in	in	ADP
dpc-4976	200	14	treating	treat	VERB
dpc-4976	200	15	moderate	moderate	ADJ
dpc-4976	200	16	-	-	PUNCT
dpc-4976	200	17	to	to	ADP
dpc-4976	200	18	-	-	PUNCT
dpc-4976	200	19	severe	severe	ADJ
dpc-4976	200	20	psoriasis	psoriasis	NOUN
dpc-4976	200	21	,	,	PUNCT
dpc-4976	200	22	there	there	PRON
dpc-4976	200	23	are	be	VERB
dpc-4976	200	24	some	some	DET
dpc-4976	200	25	limitations	limitation	NOUN
dpc-4976	200	26	related	relate	VERB
dpc-4976	200	27	to	to	ADP
dpc-4976	200	28	this	this	DET
dpc-4976	200	29	study	study	NOUN
dpc-4976	200	30	.	.	PUNCT
dpc-4976	201	1	the	the	DET
dpc-4976	201	2	limited	limited	ADJ
dpc-4976	201	3	sample	sample	NOUN
dpc-4976	201	4	size	size	NOUN
dpc-4976	201	5	and	and	CCONJ
dpc-4976	201	6	absence	absence	NOUN
dpc-4976	201	7	of	of	ADP
dpc-4976	201	8	a	a	DET
dpc-4976	201	9	control	control	NOUN
dpc-4976	201	10	group	group	NOUN
dpc-4976	201	11	restrict	restrict	VERB
dpc-4976	201	12	the	the	DET
dpc-4976	201	13	generalizability	generalizability	NOUN
dpc-4976	201	14	and	and	CCONJ
dpc-4976	201	15	causal	causal	ADJ
dpc-4976	201	16	inferences	inference	NOUN
dpc-4976	201	17	of	of	ADP
dpc-4976	201	18	the	the	DET
dpc-4976	201	19	results	result	NOUN
dpc-4976	201	20	.	.	PUNCT
dpc-4976	202	1	also	also	ADV
dpc-4976	202	2	,	,	PUNCT
dpc-4976	202	3	the	the	DET
dpc-4976	202	4	focus	focus	NOUN
dpc-4976	202	5	on	on	ADP
dpc-4976	202	6	one	one	NUM
dpc-4976	202	7	geographic	geographic	ADJ
dpc-4976	202	8	area	area	NOUN
dpc-4976	202	9	limits	limit	VERB
dpc-4976	202	10	applicability	applicability	NOUN
dpc-4976	202	11	to	to	ADP
dpc-4976	202	12	other	other	ADJ
dpc-4976	202	13	populations	population	NOUN
dpc-4976	202	14	.	.	PUNCT
dpc-4976	203	1	additionally	additionally	ADV
dpc-4976	203	2	,	,	PUNCT
dpc-4976	203	3	the	the	DET
dpc-4976	203	4	follow	follow	VERB
dpc-4976	203	5	-	-	PUNCT
dpc-4976	203	6	up	up	ADP
dpc-4976	203	7	duration	duration	NOUN
dpc-4976	203	8	,	,	PUNCT
dpc-4976	203	9	while	while	SCONJ
dpc-4976	203	10	informative	informative	ADJ
dpc-4976	203	11	,	,	PUNCT
dpc-4976	203	12	would	would	AUX
dpc-4976	203	13	benefit	benefit	VERB
dpc-4976	203	14	from	from	ADP
dpc-4976	203	15	extension	extension	NOUN
dpc-4976	203	16	to	to	PART
dpc-4976	203	17	better	well	ADV
dpc-4976	203	18	understand	understand	VERB
dpc-4976	203	19	the	the	DET
dpc-4976	203	20	long	long	ADJ
dpc-4976	203	21	-	-	PUNCT
dpc-4976	203	22	term	term	NOUN
dpc-4976	203	23	efficacy	efficacy	NOUN
dpc-4976	203	24	and	and	CCONJ
dpc-4976	203	25	safety	safety	NOUN
dpc-4976	203	26	of	of	ADP
dpc-4976	203	27	bimekizumab	bimekizumab	NOUN
dpc-4976	203	28	.	.	PUNCT
dpc-4976	204	1	future	future	ADJ
dpc-4976	204	2	research	research	NOUN
dpc-4976	204	3	will	will	AUX
dpc-4976	204	4	focus	focus	VERB
dpc-4976	204	5	on	on	ADP
dpc-4976	204	6	larger	large	ADJ
dpc-4976	204	7	cohorts	cohort	NOUN
dpc-4976	204	8	with	with	ADP
dpc-4976	204	9	different	different	ADJ
dpc-4976	204	10	characteristics	characteristic	NOUN
dpc-4976	204	11	and	and	CCONJ
dpc-4976	204	12	longer	long	ADV
dpc-4976	204	13	follow	follow	VERB
dpc-4976	204	14	-	-	PUNCT
dpc-4976	204	15	up	up	ADP
dpc-4976	204	16	periods	period	NOUN
dpc-4976	204	17	to	to	PART
dpc-4976	204	18	confirm	confirm	VERB
dpc-4976	204	19	these	these	DET
dpc-4976	204	20	findings	finding	NOUN
dpc-4976	204	21	and	and	CCONJ
dpc-4976	204	22	further	far	ADV
dpc-4976	204	23	elucidate	elucidate	VERB
dpc-4976	204	24	the	the	DET
dpc-4976	204	25	long	long	ADJ
dpc-4976	204	26	-	-	PUNCT
dpc-4976	204	27	term	term	NOUN
dpc-4976	204	28	benefits	benefit	NOUN
dpc-4976	204	29	associated	associate	VERB
dpc-4976	204	30	with	with	ADP
dpc-4976	204	31	bimekizumab	bimekizumab	PROPN
dpc-4976	204	32	.	.	PUNCT
dpc-4976	205	1	figure	figure	VERB
dpc-4976	205	2	7	7	NUM
dpc-4976	205	3	.	.	PUNCT
dpc-4976	206	1	(	(	PUNCT
dpc-4976	206	2	a	a	X
dpc-4976	206	3	)	)	PUNCT
dpc-4976	206	4	mean	mean	ADJ
dpc-4976	206	5	pasi	pasi	NOUN
dpc-4976	206	6	subscore	subscore	ADV
dpc-4976	206	7	for	for	ADP
dpc-4976	206	8	lower	low	ADJ
dpc-4976	206	9	limb	limb	NOUN
dpc-4976	206	10	over	over	ADP
dpc-4976	206	11	time	time	NOUN
dpc-4976	206	12	.	.	PUNCT
dpc-4976	207	1	pasi	pasi	NOUN
dpc-4976	207	2	subscore	subscore	ADV
dpc-4976	207	3	for	for	ADP
dpc-4976	207	4	the	the	DET
dpc-4976	207	5	lower	low	ADJ
dpc-4976	207	6	limb	limb	NOUN
dpc-4976	207	7	over	over	ADP
dpc-4976	207	8	time	time	NOUN
dpc-4976	207	9	for	for	ADP
dpc-4976	207	10	all	all	DET
dpc-4976	207	11	enrolled	enrol	VERB
dpc-4976	207	12	patients	patient	NOUN
dpc-4976	207	13	.	.	PUNCT
dpc-4976	208	1	the	the	DET
dpc-4976	208	2	scores	score	NOUN
dpc-4976	208	3	were	be	AUX
dpc-4976	208	4	recorded	record	VERB
dpc-4976	208	5	at	at	ADP
dpc-4976	208	6	baseline	baseline	NOUN
dpc-4976	208	7	,	,	PUNCT
dpc-4976	208	8	week	week	NOUN
dpc-4976	208	9	4	4	NUM
dpc-4976	208	10	(	(	PUNCT
dpc-4976	208	11	w4	w4	NOUN
dpc-4976	208	12	)	)	PUNCT
dpc-4976	208	13	,	,	PUNCT
dpc-4976	208	14	week	week	NOUN
dpc-4976	208	15	16	16	NUM
dpc-4976	208	16	(	(	PUNCT
dpc-4976	208	17	w16	w16	NOUN
dpc-4976	208	18	)	)	PUNCT
dpc-4976	208	19	,	,	PUNCT
dpc-4976	208	20	week	week	NOUN
dpc-4976	208	21	24	24	NUM
dpc-4976	208	22	(	(	PUNCT
dpc-4976	208	23	w24	w24	PROPN
dpc-4976	208	24	)	)	PUNCT
dpc-4976	208	25	,	,	PUNCT
dpc-4976	208	26	and	and	CCONJ
dpc-4976	208	27	week	week	NOUN
dpc-4976	208	28	52	52	NUM
dpc-4976	208	29	(	(	PUNCT
dpc-4976	208	30	w52	w52	NOUN
dpc-4976	208	31	)	)	PUNCT
dpc-4976	208	32	.	.	PUNCT
dpc-4976	209	1	(	(	PUNCT
dpc-4976	209	2	b	b	X
dpc-4976	209	3	)	)	PUNCT
dpc-4976	209	4	percentage	percentage	NOUN
dpc-4976	209	5	of	of	ADP
dpc-4976	209	6	patients	patient	NOUN
dpc-4976	209	7	achieving	achieve	VERB
dpc-4976	209	8	pasi	pasi	NOUN
dpc-4976	209	9	100	100	NUM
dpc-4976	209	10	subscore	subscore	ADV
dpc-4976	209	11	for	for	ADP
dpc-4976	209	12	lower	low	ADJ
dpc-4976	209	13	limb	limb	NOUN
dpc-4976	209	14	over	over	ADP
dpc-4976	209	15	time	time	NOUN
dpc-4976	209	16	.	.	PUNCT
dpc-4976	210	1	patients	patient	NOUN
dpc-4976	210	2	achieving	achieve	VERB
dpc-4976	210	3	a	a	DET
dpc-4976	210	4	pasi	pasi	NOUN
dpc-4976	210	5	100	100	NUM
dpc-4976	210	6	subscore	subscore	ADJ
dpc-4976	210	7	(	(	PUNCT
dpc-4976	210	8	complete	complete	ADJ
dpc-4976	210	9	clearance	clearance	NOUN
dpc-4976	210	10	of	of	ADP
dpc-4976	210	11	psoriasis	psoriasis	NOUN
dpc-4976	210	12	)	)	PUNCT
dpc-4976	210	13	for	for	ADP
dpc-4976	210	14	the	the	DET
dpc-4976	210	15	lower	low	ADJ
dpc-4976	210	16	limb	limb	NOUN
dpc-4976	210	17	over	over	ADP
dpc-4976	210	18	time	time	NOUN
dpc-4976	210	19	.	.	PUNCT
dpc-4976	211	1	the	the	DET
dpc-4976	211	2	percentages	percentage	NOUN
dpc-4976	211	3	were	be	AUX
dpc-4976	211	4	recorded	record	VERB
dpc-4976	211	5	at	at	ADP
dpc-4976	211	6	w4	w4	NOUN
dpc-4976	211	7	,	,	PUNCT
dpc-4976	211	8	w16	w16	PROPN
dpc-4976	211	9	,	,	PUNCT
dpc-4976	211	10	w24	w24	PROPN
dpc-4976	211	11	,	,	PUNCT
dpc-4976	211	12	and	and	CCONJ
dpc-4976	211	13	w52	w52	NOUN
dpc-4976	211	14	.	.	PUNCT
dpc-4976	212	1	10	10	NUM
dpc-4976	212	2	original	original	ADJ
dpc-4976	212	3	article	article	NOUN
dpc-4976	212	4	|	|	ADV
dpc-4976	212	5	dermatol	dermatol	ADJ
dpc-4976	212	6	pract	pract	NOUN
dpc-4976	212	7	concept	concept	NOUN
dpc-4976	212	8	.	.	PUNCT
dpc-4976	213	1	2025;15(1):4976	2025;15(1):4976	PROPN
dpc-4976	213	2	a	a	DET
dpc-4976	213	3	multicentre	multicentre	NOUN
dpc-4976	213	4	,	,	PUNCT
dpc-4976	213	5	double	double	ADJ
dpc-4976	213	6	-	-	PUNCT
dpc-4976	213	7	blind	blind	ADJ
dpc-4976	213	8	,	,	PUNCT
dpc-4976	213	9	placebo	placebo	NOUN
dpc-4976	213	10	-	-	PUNCT
dpc-4976	213	11	controlled	control	VERB
dpc-4976	213	12	,	,	PUNCT
dpc-4976	213	13	randomised	randomise	VERB
dpc-4976	213	14	withdrawal	withdrawal	NOUN
dpc-4976	213	15	phase	phase	NOUN
dpc-4976	213	16	3	3	NUM
dpc-4976	213	17	trial	trial	NOUN
dpc-4976	213	18	.	.	PUNCT
dpc-4976	214	1	lancet	lancet	PROPN
dpc-4976	214	2	.	.	PUNCT
dpc-4976	215	1	2021;397(10273):475–486	2021;397(10273):475–486	NUM
dpc-4976	215	2	.	.	PUNCT
dpc-4976	215	3	doi	doi	NOUN
dpc-4976	215	4	:	:	PUNCT
dpc-4976	215	5	10.1016	10.1016	NUM
dpc-4976	215	6	/	/	SYM
dpc-4976	215	7	s0140	s0140	PROPN
dpc-4976	215	8	-	-	PUNCT
dpc-4976	215	9	6736(21)00126	6736(21)00126	NUM
dpc-4976	215	10	-	-	PUNCT
dpc-4976	215	11	4	4	NUM
dpc-4976	215	12	.	.	NOUN
dpc-4976	215	13	15	15	NUM
dpc-4976	215	14	.	.	PUNCT
dpc-4976	216	1	reich	reich	PROPN
dpc-4976	216	2	k	k	PROPN
dpc-4976	216	3	,	,	PUNCT
dpc-4976	216	4	papp	papp	PROPN
dpc-4976	216	5	ka	ka	PROPN
dpc-4976	216	6	,	,	PUNCT
dpc-4976	216	7	blauvelt	blauvelt	VERB
dpc-4976	216	8	a	a	PRON
dpc-4976	216	9	,	,	PUNCT
dpc-4976	216	10	et	et	PROPN
dpc-4976	216	11	al	al	PROPN
dpc-4976	216	12	.	.	PROPN
dpc-4976	216	13	bimekizumab	bimekizumab	PROPN
dpc-4976	216	14	versus	versus	ADP
dpc-4976	216	15	ustekinumab	ustekinumab	NOUN
dpc-4976	216	16	for	for	ADP
dpc-4976	216	17	the	the	DET
dpc-4976	216	18	treatment	treatment	NOUN
dpc-4976	216	19	of	of	ADP
dpc-4976	216	20	moderate	moderate	ADJ
dpc-4976	216	21	to	to	ADP
dpc-4976	216	22	severe	severe	ADJ
dpc-4976	216	23	plaque	plaque	NOUN
dpc-4976	216	24	psoriasis	psoriasis	NOUN
dpc-4976	216	25	(	(	PUNCT
dpc-4976	216	26	be	be	AUX
dpc-4976	216	27	vivid	vivid	ADJ
dpc-4976	216	28	):	):	PUNCT
dpc-4976	216	29	efficacy	efficacy	NOUN
dpc-4976	216	30	and	and	CCONJ
dpc-4976	216	31	safety	safety	NOUN
dpc-4976	216	32	from	from	ADP
dpc-4976	216	33	a	a	DET
dpc-4976	216	34	52	52	NUM
dpc-4976	216	35	-	-	PUNCT
dpc-4976	216	36	week	week	NOUN
dpc-4976	216	37	,	,	PUNCT
dpc-4976	216	38	multicentre	multicentre	NOUN
dpc-4976	216	39	,	,	PUNCT
dpc-4976	216	40	double	double	ADJ
dpc-4976	216	41	-	-	PUNCT
dpc-4976	216	42	blind	blind	ADJ
dpc-4976	216	43	,	,	PUNCT
dpc-4976	216	44	active	active	ADJ
dpc-4976	216	45	comparator	comparator	NOUN
dpc-4976	216	46	and	and	CCONJ
dpc-4976	216	47	placebo	placebo	NOUN
dpc-4976	216	48	controlled	control	VERB
dpc-4976	216	49	phase	phase	NOUN
dpc-4976	216	50	3	3	NUM
dpc-4976	216	51	trial	trial	NOUN
dpc-4976	216	52	.	.	PUNCT
dpc-4976	217	1	lancet	lancet	NOUN
dpc-4976	217	2	.	.	PUNCT
dpc-4976	218	1	2021;397(10273):487–498	2021;397(10273):487–498	X
dpc-4976	218	2	.	.	PUNCT
dpc-4976	219	1	doi	doi	NOUN
dpc-4976	219	2	:	:	PUNCT
dpc-4976	219	3	10.1016	10.1016	NUM
dpc-4976	219	4	/	/	SYM
dpc-4976	219	5	s0140	s0140	PROPN
dpc-4976	219	6	6736(21)00125	6736(21)00125	NUM
dpc-4976	219	7	-	-	SYM
dpc-4976	219	8	2	2	NUM
dpc-4976	219	9	.	.	NOUN
dpc-4976	219	10	16	16	NUM
dpc-4976	219	11	.	.	PUNCT
dpc-4976	220	1	orsini	orsini	PROPN
dpc-4976	220	2	d	d	PROPN
dpc-4976	220	3	,	,	PUNCT
dpc-4976	220	4	megna	megna	PROPN
dpc-4976	220	5	m	m	PROPN
dpc-4976	220	6	,	,	PUNCT
dpc-4976	220	7	assorgi	assorgi	PROPN
dpc-4976	220	8	c	c	NOUN
dpc-4976	220	9	,	,	PUNCT
dpc-4976	220	10	et	et	PROPN
dpc-4976	220	11	al	al	PROPN
dpc-4976	220	12	.	.	PROPN
dpc-4976	220	13	efficacy	efficacy	NOUN
dpc-4976	220	14	and	and	CCONJ
dpc-4976	220	15	safety	safety	NOUN
dpc-4976	220	16	of	of	ADP
dpc-4976	220	17	bimekizumab	bimekizumab	NOUN
dpc-4976	220	18	in	in	ADP
dpc-4976	220	19	elderly	elderly	ADJ
dpc-4976	220	20	patients	patient	NOUN
dpc-4976	220	21	:	:	PUNCT
dpc-4976	220	22	real	real	ADJ
dpc-4976	220	23	-	-	PUNCT
dpc-4976	220	24	world	world	NOUN
dpc-4976	220	25	multicenter	multicenter	NOUN
dpc-4976	220	26	retrospective	retrospective	ADJ
dpc-4976	220	27	study	study	NOUN
dpc-4976	220	28	—	—	PUNCT
dpc-4976	220	29	il	il	PROPN
dpc-4976	220	30	pso	pso	NOUN
dpc-4976	220	31	(	(	PUNCT
dpc-4976	220	32	italian	italian	ADJ
dpc-4976	220	33	landscape	landscape	NOUN
dpc-4976	220	34	psoriasis	psoriasis	NOUN
dpc-4976	220	35	)	)	PUNCT
dpc-4976	220	36	.	.	PUNCT
dpc-4976	221	1	j	j	PROPN
dpc-4976	221	2	dermatolog	dermatolog	PROPN
dpc-4976	221	3	treat	treat	NOUN
dpc-4976	221	4	.	.	PUNCT
dpc-4976	222	1	2024;35(1	2024;35(1	NUM
dpc-4976	222	2	)	)	PUNCT
dpc-4976	222	3	.	.	PUNCT
dpc-4976	223	1	doi	doi	NOUN
dpc-4976	223	2	:	:	PUNCT
dpc-4976	223	3	10.1080/09546634.2024	10.1080/09546634.2024	NUM
dpc-4976	223	4	.	.	NOUN
dpc-4976	223	5	2393376	2393376	NUM
dpc-4976	223	6	.	.	PUNCT
dpc-4976	224	1	17	17	NUM
dpc-4976	224	2	.	.	PUNCT
dpc-4976	225	1	hagino	hagino	PROPN
dpc-4976	225	2	t	t	PROPN
dpc-4976	225	3	,	,	PUNCT
dpc-4976	225	4	saeki	saeki	PROPN
dpc-4976	225	5	h	h	PROPN
dpc-4976	225	6	,	,	PUNCT
dpc-4976	225	7	fujimoto	fujimoto	PROPN
dpc-4976	225	8	e	e	PROPN
dpc-4976	225	9	,	,	PUNCT
dpc-4976	225	10	kanda	kanda	PROPN
dpc-4976	225	11	n.	n.	PROPN
dpc-4976	225	12	real	real	ADJ
dpc-4976	225	13	-	-	PUNCT
dpc-4976	225	14	world	world	NOUN
dpc-4976	225	15	effectiveness	effectiveness	NOUN
dpc-4976	225	16	and	and	CCONJ
dpc-4976	225	17	safety	safety	NOUN
dpc-4976	225	18	of	of	ADP
dpc-4976	225	19	bimekizumab	bimekizumab	NOUN
dpc-4976	225	20	in	in	ADP
dpc-4976	225	21	japanese	japanese	ADJ
dpc-4976	225	22	patients	patient	NOUN
dpc-4976	225	23	with	with	ADP
dpc-4976	225	24	psoriasis	psoriasis	NOUN
dpc-4976	225	25	:	:	PUNCT
dpc-4976	225	26	a	a	DET
dpc-4976	225	27	single	single	ADJ
dpc-4976	225	28	-	-	PUNCT
dpc-4976	225	29	center	center	NOUN
dpc-4976	225	30	retrospective	retrospective	ADJ
dpc-4976	225	31	study	study	NOUN
dpc-4976	225	32	.	.	PUNCT
dpc-4976	226	1	j	j	PROPN
dpc-4976	226	2	dermatol	dermatol	NOUN
dpc-4976	226	3	.	.	PUNCT
dpc-4976	227	1	published	publish	VERB
dpc-4976	227	2	online	online	ADV
dpc-4976	227	3	may	may	PROPN
dpc-4976	227	4	1	1	NUM
dpc-4976	227	5	,	,	PUNCT
dpc-4976	227	6	2024	2024	NUM
dpc-4976	227	7	.	.	PUNCT
dpc-4976	228	1	doi	doi	NOUN
dpc-4976	228	2	:	:	PUNCT
dpc-4976	228	3	10.1111/1346	10.1111/1346	NUM
dpc-4976	228	4	-	-	NUM
dpc-4976	228	5	8138.17186	8138.17186	ADJ
dpc-4976	228	6	.	.	PUNCT
dpc-4976	229	1	18	18	NUM
dpc-4976	229	2	.	.	PUNCT
dpc-4976	229	3	warren	warren	PROPN
dpc-4976	229	4	rb	rb	PROPN
dpc-4976	229	5	,	,	PUNCT
dpc-4976	229	6	blauvelt	blauvelt	VERB
dpc-4976	229	7	a	a	DET
dpc-4976	229	8	,	,	PUNCT
dpc-4976	229	9	bagel	bagel	NOUN
dpc-4976	229	10	j	j	PROPN
dpc-4976	229	11	,	,	PUNCT
dpc-4976	229	12	et	et	PROPN
dpc-4976	229	13	al	al	PROPN
dpc-4976	229	14	.	.	PROPN
dpc-4976	229	15	bimekizumab	bimekizumab	PROPN
dpc-4976	229	16	versus	versus	ADP
dpc-4976	229	17	adalimumab	adalimumab	NOUN
dpc-4976	229	18	in	in	ADP
dpc-4976	229	19	plaque	plaque	NOUN
dpc-4976	229	20	psoriasis	psoriasis	NOUN
dpc-4976	229	21	.	.	PUNCT
dpc-4976	230	1	n	n	PROPN
dpc-4976	230	2	engl	engl	PROPN
dpc-4976	230	3	j	j	PROPN
dpc-4976	230	4	med	med	PROPN
dpc-4976	230	5	.	.	PUNCT
dpc-4976	231	1	2021;385(2	2021;385(2	NUM
dpc-4976	231	2	):	):	PUNCT
dpc-4976	231	3	130–141	130–141	NUM
dpc-4976	231	4	.	.	PUNCT
dpc-4976	232	1	doi	doi	NOUN
dpc-4976	232	2	:	:	PUNCT
dpc-4976	232	3	10.1056	10.1056	NUM
dpc-4976	232	4	/	/	SYM
dpc-4976	232	5	nejmoa2103520	nejmoa2103520	PROPN
dpc-4976	232	6	.	.	PROPN
dpc-4976	233	1	19	19	NUM
dpc-4976	233	2	.	.	PUNCT
dpc-4976	233	3	reich	reich	PROPN
dpc-4976	233	4	k	k	PROPN
dpc-4976	233	5	,	,	PUNCT
dpc-4976	233	6	warren	warren	PROPN
dpc-4976	233	7	rb	rb	PROPN
dpc-4976	233	8	,	,	PUNCT
dpc-4976	233	9	lebwohl	lebwohl	NOUN
dpc-4976	233	10	m	m	PROPN
dpc-4976	233	11	,	,	PUNCT
dpc-4976	233	12	et	et	PROPN
dpc-4976	233	13	al	al	PROPN
dpc-4976	233	14	.	.	PROPN
dpc-4976	233	15	bimekizumab	bimekizumab	PROPN
dpc-4976	233	16	versus	versus	ADP
dpc-4976	233	17	secukinumab	secukinumab	NOUN
dpc-4976	233	18	in	in	ADP
dpc-4976	233	19	plaque	plaque	NOUN
dpc-4976	233	20	psoriasis	psoriasis	NOUN
dpc-4976	233	21	.	.	PUNCT
dpc-4976	234	1	n	n	PROPN
dpc-4976	234	2	engl	engl	PROPN
dpc-4976	234	3	j	j	PROPN
dpc-4976	234	4	med	med	PROPN
dpc-4976	234	5	.	.	PUNCT
dpc-4976	235	1	2021;385(2	2021;385(2	NUM
dpc-4976	235	2	):	):	PUNCT
dpc-4976	236	1	142–152	142–152	NUM
dpc-4976	236	2	.	.	PUNCT
dpc-4976	237	1	doi	doi	NOUN
dpc-4976	237	2	:	:	PUNCT
dpc-4976	237	3	10.1056	10.1056	NUM
dpc-4976	237	4	/	/	SYM
dpc-4976	237	5	nejmoa2102388	nejmoa2102388	PROPN
dpc-4976	237	6	.	.	PROPN
dpc-4976	238	1	20	20	NUM
dpc-4976	238	2	.	.	PUNCT
dpc-4976	239	1	gordon	gordon	PROPN
dpc-4976	239	2	kb	kb	PROPN
dpc-4976	239	3	,	,	PUNCT
dpc-4976	239	4	strober	strober	ADV
dpc-4976	239	5	b	b	NUM
dpc-4976	239	6	,	,	PUNCT
dpc-4976	239	7	lebwohl	lebwohl	NOUN
dpc-4976	239	8	m	m	PROPN
dpc-4976	239	9	,	,	PUNCT
dpc-4976	239	10	et	et	PROPN
dpc-4976	239	11	al	al	PROPN
dpc-4976	239	12	.	.	PROPN
dpc-4976	239	13	efficacy	efficacy	NOUN
dpc-4976	239	14	and	and	CCONJ
dpc-4976	239	15	safety	safety	NOUN
dpc-4976	239	16	of	of	ADP
dpc-4976	239	17	bimekizumab	bimekizumab	NOUN
dpc-4976	239	18	in	in	ADP
dpc-4976	239	19	patients	patient	NOUN
dpc-4976	239	20	with	with	ADP
dpc-4976	239	21	moderate	moderate	ADJ
dpc-4976	239	22	-	-	PUNCT
dpc-4976	239	23	to	to	ADP
dpc-4976	239	24	-	-	PUNCT
dpc-4976	239	25	severe	severe	ADJ
dpc-4976	239	26	plaque	plaque	NOUN
dpc-4976	239	27	psoriasis	psoriasis	NOUN
dpc-4976	239	28	for	for	ADP
dpc-4976	239	29	up	up	ADP
dpc-4976	239	30	to	to	PART
dpc-4976	239	31	2	2	NUM
dpc-4976	239	32	years	year	NOUN
dpc-4976	239	33	:	:	PUNCT
dpc-4976	239	34	results	result	NOUN
dpc-4976	239	35	from	from	ADP
dpc-4976	239	36	the	the	DET
dpc-4976	239	37	be	be	AUX
dpc-4976	239	38	bright	bright	ADJ
dpc-4976	239	39	long	long	ADJ
dpc-4976	239	40	-	-	PUNCT
dpc-4976	239	41	term	term	NOUN
dpc-4976	239	42	extension	extension	NOUN
dpc-4976	239	43	study	study	NOUN
dpc-4976	239	44	.	.	PUNCT
dpc-4976	240	1	br	br	PROPN
dpc-4976	240	2	j	j	PROPN
dpc-4976	240	3	dermatol	dermatol	NOUN
dpc-4976	240	4	.	.	PUNCT
dpc-4976	241	1	2023;188(1):44–53	2023;188(1):44–53	X
dpc-4976	241	2	.	.	PUNCT
dpc-4976	242	1	doi	doi	NOUN
dpc-4976	242	2	:	:	PUNCT
dpc-4976	242	3	10.1111	10.1111	NUM
dpc-4976	242	4	/bjd.21892	/bjd.21892	NOUN
dpc-4976	242	5	.	.	PUNCT
dpc-4976	243	1	21	21	NUM
dpc-4976	243	2	.	.	PUNCT
dpc-4976	243	3	reich	reich	PROPN
dpc-4976	243	4	k	k	PROPN
dpc-4976	243	5	,	,	PUNCT
dpc-4976	243	6	gooderham	gooderham	PROPN
dpc-4976	243	7	m	m	PROPN
dpc-4976	243	8	,	,	PUNCT
dpc-4976	243	9	thaçi	thaçi	PROPN
dpc-4976	243	10	d	d	PROPN
dpc-4976	243	11	,	,	PUNCT
dpc-4976	243	12	et	et	PROPN
dpc-4976	243	13	al	al	PROPN
dpc-4976	243	14	.	.	PROPN
dpc-4976	243	15	efficacy	efficacy	NOUN
dpc-4976	243	16	and	and	CCONJ
dpc-4976	243	17	safety	safety	NOUN
dpc-4976	243	18	of	of	ADP
dpc-4976	243	19	bimekizumab	bimekizumab	NOUN
dpc-4976	243	20	in	in	ADP
dpc-4976	243	21	patients	patient	NOUN
dpc-4976	243	22	with	with	ADP
dpc-4976	243	23	moderate	moderate	ADJ
dpc-4976	243	24	-	-	PUNCT
dpc-4976	243	25	to	to	ADP
dpc-4976	243	26	-	-	PUNCT
dpc-4976	243	27	severe	severe	ADJ
dpc-4976	243	28	plaque	plaque	NOUN
dpc-4976	243	29	psoriasis	psoriasis	NOUN
dpc-4976	243	30	for	for	ADP
dpc-4976	243	31	up	up	ADP
dpc-4976	243	32	to	to	PART
dpc-4976	243	33	2	2	NUM
dpc-4976	243	34	years	year	NOUN
dpc-4976	243	35	:	:	PUNCT
dpc-4976	243	36	results	result	NOUN
dpc-4976	243	37	from	from	ADP
dpc-4976	243	38	the	the	DET
dpc-4976	243	39	be	be	AUX
dpc-4976	243	40	radiant	radiant	ADJ
dpc-4976	243	41	long	long	ADJ
dpc-4976	243	42	-	-	PUNCT
dpc-4976	243	43	term	term	NOUN
dpc-4976	243	44	extension	extension	NOUN
dpc-4976	243	45	study	study	NOUN
dpc-4976	243	46	.	.	PUNCT
dpc-4976	244	1	br	br	PROPN
dpc-4976	244	2	j	j	PROPN
dpc-4976	244	3	dermatol	dermatol	NOUN
dpc-4976	244	4	.	.	PUNCT
dpc-4976	245	1	2023;188(1):54–63	2023;188(1):54–63	NUM
dpc-4976	245	2	.	.	PUNCT
dpc-4976	246	1	doi	doi	NOUN
dpc-4976	246	2	:	:	PUNCT
dpc-4976	246	3	10.1111	10.1111	NUM
dpc-4976	246	4	/bjd.21893	/bjd.21893	NOUN
dpc-4976	246	5	.	.	PUNCT
dpc-4976	247	1	22	22	NUM
dpc-4976	247	2	.	.	PUNCT
dpc-4976	248	1	griffiths	griffiths	PROPN
dpc-4976	248	2	cem	cem	PROPN
dpc-4976	248	3	,	,	PUNCT
dpc-4976	248	4	strober	strober	ADV
dpc-4976	248	5	b	b	NUM
dpc-4976	248	6	,	,	PUNCT
dpc-4976	248	7	lebwohl	lebwohl	NOUN
dpc-4976	248	8	m	m	PROPN
dpc-4976	248	9	,	,	PUNCT
dpc-4976	248	10	et	et	PROPN
dpc-4976	248	11	al	al	PROPN
dpc-4976	248	12	.	.	PROPN
dpc-4976	248	13	efficacy	efficacy	NOUN
dpc-4976	248	14	and	and	CCONJ
dpc-4976	248	15	safety	safety	NOUN
dpc-4976	248	16	of	of	ADP
dpc-4976	248	17	bimekizumab	bimekizumab	NOUN
dpc-4976	248	18	in	in	ADP
dpc-4976	248	19	patients	patient	NOUN
dpc-4976	248	20	with	with	ADP
dpc-4976	248	21	moderate	moderate	ADJ
dpc-4976	248	22	-	-	PUNCT
dpc-4976	248	23	to	to	ADP
dpc-4976	248	24	-	-	PUNCT
dpc-4976	248	25	severe	severe	ADJ
dpc-4976	248	26	plaque	plaque	NOUN
dpc-4976	248	27	psoriasis	psoriasis	NOUN
dpc-4976	248	28	for	for	ADP
dpc-4976	248	29	up	up	ADP
dpc-4976	248	30	to	to	PART
dpc-4976	248	31	2	2	NUM
dpc-4976	248	32	years	year	NOUN
dpc-4976	248	33	:	:	PUNCT
dpc-4976	248	34	results	result	NOUN
dpc-4976	248	35	from	from	ADP
dpc-4976	248	36	the	the	DET
dpc-4976	248	37	be	be	AUX
dpc-4976	248	38	sure	sure	ADJ
dpc-4976	248	39	longterm	longterm	NOUN
dpc-4976	248	40	extension	extension	NOUN
dpc-4976	248	41	study	study	NOUN
dpc-4976	248	42	.	.	PUNCT
dpc-4976	249	1	br	br	PROPN
dpc-4976	249	2	j	j	PROPN
dpc-4976	249	3	dermatol	dermatol	NOUN
dpc-4976	249	4	.	.	PUNCT
dpc-4976	250	1	2023;188(1):64–73	2023;188(1):64–73	X
dpc-4976	250	2	.	.	PUNCT
dpc-4976	251	1	doi	doi	NOUN
dpc-4976	251	2	:	:	PUNCT
dpc-4976	251	3	10.1111	10.1111	NUM
dpc-4976	251	4	/	/	SYM
dpc-4976	251	5	bjd.21894	bjd.21894	NOUN
dpc-4976	251	6	.	.	PROPN
dpc-4976	251	7	23	23	NUM
dpc-4976	251	8	.	.	PUNCT
dpc-4976	252	1	merola	merola	PROPN
dpc-4976	252	2	jf	jf	PROPN
dpc-4976	252	3	,	,	PUNCT
dpc-4976	252	4	landewé	landewé	NOUN
dpc-4976	252	5	r	r	PROPN
dpc-4976	252	6	,	,	PUNCT
dpc-4976	252	7	mcinnes	mcinne	NOUN
dpc-4976	252	8	ib	ib	PROPN
dpc-4976	252	9	,	,	PUNCT
dpc-4976	252	10	et	et	PROPN
dpc-4976	252	11	al	al	PROPN
dpc-4976	252	12	.	.	PROPN
dpc-4976	252	13	bimekizumab	bimekizumab	PROPN
dpc-4976	252	14	in	in	ADP
dpc-4976	252	15	patients	patient	NOUN
dpc-4976	252	16	with	with	ADP
dpc-4976	252	17	active	active	ADJ
dpc-4976	252	18	psoriatic	psoriatic	ADJ
dpc-4976	252	19	arthritis	arthritis	NOUN
dpc-4976	252	20	and	and	CCONJ
dpc-4976	252	21	previous	previous	ADJ
dpc-4976	252	22	inadequate	inadequate	ADJ
dpc-4976	252	23	response	response	NOUN
dpc-4976	252	24	or	or	CCONJ
dpc-4976	252	25	intolerance	intolerance	NOUN
dpc-4976	252	26	to	to	ADP
dpc-4976	252	27	tumour	tumour	NOUN
dpc-4976	252	28	necrosis	necrosis	NOUN
dpc-4976	252	29	factor	factor	NOUN
dpc-4976	252	30	-	-	PUNCT
dpc-4976	252	31	α	α	NOUN
dpc-4976	252	32	inhibitors	inhibitor	NOUN
dpc-4976	252	33	:	:	PUNCT
dpc-4976	252	34	a	a	DET
dpc-4976	252	35	randomised	randomised	ADJ
dpc-4976	252	36	,	,	PUNCT
dpc-4976	252	37	double	double	ADJ
dpc-4976	252	38	-	-	PUNCT
dpc-4976	252	39	blind	blind	ADJ
dpc-4976	252	40	,	,	PUNCT
dpc-4976	252	41	placebo	placebo	NOUN
dpc-4976	252	42	-	-	PUNCT
dpc-4976	252	43	controlled	control	VERB
dpc-4976	252	44	,	,	PUNCT
dpc-4976	252	45	phase	phase	NOUN
dpc-4976	252	46	3	3	NUM
dpc-4976	252	47	trial	trial	NOUN
dpc-4976	252	48	(	(	PUNCT
dpc-4976	252	49	be	be	AUX
dpc-4976	252	50	complete	complete	ADJ
dpc-4976	252	51	)	)	PUNCT
dpc-4976	252	52	.	.	PUNCT
dpc-4976	252	53	  	  	SPACE
dpc-4976	252	54	lancet	lancet	VERB
dpc-4976	252	55	.	.	PUNCT
dpc-4976	253	1	2023;401(10370):38	2023;401(10370):38	NUM
dpc-4976	253	2	-	-	SYM
dpc-4976	253	3	48	48	NUM
dpc-4976	253	4	.	.	PUNCT
dpc-4976	254	1	doi:10.1016	doi:10.1016	PROPN
dpc-4976	255	1	/s0140	/s0140	PROPN
dpc-4976	255	2	-	-	PUNCT
dpc-4976	255	3	6736(22)02303	6736(22)02303	NUM
dpc-4976	255	4	-	-	SYM
dpc-4976	255	5	0	0	NUM
dpc-4976	255	6	2	2	NUM
dpc-4976	255	7	.	.	PUNCT
dpc-4976	255	8	damiani	damiani	PROPN
dpc-4976	255	9	g	g	PROPN
dpc-4976	255	10	,	,	PUNCT
dpc-4976	255	11	bragazzi	bragazzi	PROPN
dpc-4976	255	12	nl	nl	PROPN
dpc-4976	255	13	,	,	PUNCT
dpc-4976	255	14	karimkhani	karimkhani	PROPN
dpc-4976	255	15	aksut	aksut	PROPN
dpc-4976	255	16	c	c	PROPN
dpc-4976	255	17	,	,	PUNCT
dpc-4976	255	18	et	et	PROPN
dpc-4976	255	19	al	al	PROPN
dpc-4976	255	20	.	.	PUNCT
dpc-4976	256	1	the	the	DET
dpc-4976	256	2	global	global	ADJ
dpc-4976	256	3	,	,	PUNCT
dpc-4976	256	4	regional	regional	ADJ
dpc-4976	256	5	,	,	PUNCT
dpc-4976	256	6	and	and	CCONJ
dpc-4976	256	7	national	national	ADJ
dpc-4976	256	8	burden	burden	NOUN
dpc-4976	256	9	of	of	ADP
dpc-4976	256	10	psoriasis	psoriasis	NOUN
dpc-4976	256	11	:	:	PUNCT
dpc-4976	256	12	results	result	NOUN
dpc-4976	256	13	and	and	CCONJ
dpc-4976	256	14	insights	insight	NOUN
dpc-4976	256	15	from	from	ADP
dpc-4976	256	16	the	the	DET
dpc-4976	256	17	global	global	ADJ
dpc-4976	256	18	burden	burden	NOUN
dpc-4976	256	19	of	of	ADP
dpc-4976	256	20	disease	disease	NOUN
dpc-4976	256	21	2019	2019	NUM
dpc-4976	256	22	study	study	NOUN
dpc-4976	256	23	.	.	PUNCT
dpc-4976	257	1	front	front	ADJ
dpc-4976	257	2	med	med	PROPN
dpc-4976	257	3	(	(	PUNCT
dpc-4976	257	4	lausanne	lausanne	PROPN
dpc-4976	257	5	)	)	PUNCT
dpc-4976	257	6	.	.	PUNCT
dpc-4976	258	1	2021;8	2021;8	NUM
dpc-4976	258	2	.	.	PUNCT
dpc-4976	259	1	doi	doi	NOUN
dpc-4976	259	2	:	:	PUNCT
dpc-4976	259	3	10.3389	10.3389	NUM
dpc-4976	259	4	/	/	SYM
dpc-4976	259	5	fmed.2021.743180	fmed.2021.743180	NOUN
dpc-4976	259	6	.	.	PUNCT
dpc-4976	260	1	3	3	X
dpc-4976	260	2	.	.	X
dpc-4976	260	3	dattola	dattola	PROPN
dpc-4976	260	4	a	a	PRON
dpc-4976	260	5	,	,	PUNCT
dpc-4976	260	6	del	del	PROPN
dpc-4976	260	7	duca	duca	PROPN
dpc-4976	260	8	e	e	PROPN
dpc-4976	260	9	,	,	PUNCT
dpc-4976	260	10	saraceno	saraceno	PROPN
dpc-4976	260	11	r	r	PROPN
dpc-4976	260	12	,	,	PUNCT
dpc-4976	260	13	gramiccia	gramiccia	PROPN
dpc-4976	260	14	t	t	PROPN
dpc-4976	260	15	,	,	PUNCT
dpc-4976	260	16	bianchi	bianchi	PROPN
dpc-4976	260	17	l.	l.	PROPN
dpc-4976	260	18	safety	safety	PROPN
dpc-4976	260	19	evaluation	evaluation	NOUN
dpc-4976	260	20	of	of	ADP
dpc-4976	260	21	apremilast	apremilast	NOUN
dpc-4976	260	22	for	for	ADP
dpc-4976	260	23	the	the	DET
dpc-4976	260	24	treatment	treatment	NOUN
dpc-4976	260	25	of	of	ADP
dpc-4976	260	26	psoriasis	psoriasis	NOUN
dpc-4976	260	27	.	.	PUNCT
dpc-4976	261	1	expert	expert	NOUN
dpc-4976	261	2	opin	opin	NOUN
dpc-4976	261	3	drug	drug	NOUN
dpc-4976	261	4	saf	saf	PROPN
dpc-4976	261	5	.	.	PROPN
dpc-4976	261	6	2017;16(3):381–385	2017;16(3):381–385	NUM
dpc-4976	261	7	.	.	PUNCT
dpc-4976	262	1	doi	doi	NOUN
dpc-4976	262	2	:	:	PUNCT
dpc-4976	262	3	10.1080/14740	10.1080/14740	NUM
dpc-4976	262	4	338.2017.1288714	338.2017.1288714	NOUN
dpc-4976	262	5	.	.	PUNCT
dpc-4976	263	1	4	4	NUM
dpc-4976	263	2	.	.	X
dpc-4976	263	3	bu	bu	PROPN
dpc-4976	263	4	j	j	PROPN
dpc-4976	263	5	,	,	PUNCT
dpc-4976	263	6	ding	de	VERB
dpc-4976	263	7	r	r	NOUN
dpc-4976	263	8	,	,	PUNCT
dpc-4976	263	9	zhou	zhou	PROPN
dpc-4976	263	10	l	l	PROPN
dpc-4976	263	11	,	,	PUNCT
dpc-4976	263	12	chen	chen	PROPN
dpc-4976	263	13	x	x	PROPN
dpc-4976	263	14	,	,	PUNCT
dpc-4976	263	15	shen	shen	PROPN
dpc-4976	263	16	e.	e.	PROPN
dpc-4976	263	17	epidemiology	epidemiology	PROPN
dpc-4976	263	18	of	of	ADP
dpc-4976	263	19	psoriasis	psoriasis	NOUN
dpc-4976	263	20	and	and	CCONJ
dpc-4976	263	21	comorbid	comorbid	NOUN
dpc-4976	263	22	diseases	disease	NOUN
dpc-4976	263	23	:	:	PUNCT
dpc-4976	263	24	a	a	DET
dpc-4976	263	25	narrative	narrative	NOUN
dpc-4976	263	26	review	review	NOUN
dpc-4976	263	27	.	.	PUNCT
dpc-4976	264	1	front	front	ADJ
dpc-4976	264	2	immunol	immunol	NOUN
dpc-4976	264	3	.	.	PUNCT
dpc-4976	265	1	2022;13	2022;13	NUM
dpc-4976	265	2	.	.	PUNCT
dpc-4976	265	3	doi	doi	NOUN
dpc-4976	265	4	:	:	PUNCT
dpc-4976	265	5	10.3389	10.3389	NUM
dpc-4976	265	6	/	/	SYM
dpc-4976	265	7	fimmu.2022.880201	fimmu.2022.880201	NOUN
dpc-4976	265	8	.	.	PUNCT
dpc-4976	266	1	5	5	NUM
dpc-4976	266	2	.	.	X
dpc-4976	266	3	brembilla	brembilla	PROPN
dpc-4976	266	4	nc	nc	PROPN
dpc-4976	266	5	,	,	PUNCT
dpc-4976	266	6	senra	senra	NOUN
dpc-4976	266	7	l	l	NOUN
dpc-4976	266	8	,	,	PUNCT
dpc-4976	266	9	boehncke	boehncke	NOUN
dpc-4976	266	10	wh	wh	PROPN
dpc-4976	266	11	.	.	PUNCT
dpc-4976	267	1	the	the	DET
dpc-4976	267	2	il-17	il-17	NUM
dpc-4976	267	3	family	family	NOUN
dpc-4976	267	4	of	of	ADP
dpc-4976	267	5	cytokines	cytokine	NOUN
dpc-4976	267	6	in	in	ADP
dpc-4976	267	7	psoriasis	psoriasis	NOUN
dpc-4976	267	8	:	:	PUNCT
dpc-4976	267	9	il-17a	il-17a	PROPN
dpc-4976	267	10	and	and	CCONJ
dpc-4976	267	11	beyond	beyond	ADP
dpc-4976	267	12	.	.	PUNCT
dpc-4976	268	1	front	front	ADJ
dpc-4976	268	2	immunol	immunol	NOUN
dpc-4976	268	3	.	.	PUNCT
dpc-4976	269	1	2018;9	2018;9	NUM
dpc-4976	269	2	.	.	PUNCT
dpc-4976	270	1	doi	doi	NOUN
dpc-4976	270	2	:	:	PUNCT
dpc-4976	271	1	10.3389	10.3389	NUM
dpc-4976	271	2	/	/	SYM
dpc-4976	271	3	fimmu.2018.01682	fimmu.2018.01682	ADJ
dpc-4976	271	4	.	.	PUNCT
dpc-4976	272	1	6	6	X
dpc-4976	272	2	.	.	X
dpc-4976	272	3	bunte	bunte	PROPN
dpc-4976	272	4	k	k	PROPN
dpc-4976	272	5	,	,	PUNCT
dpc-4976	272	6	beikler	beikler	ADJ
dpc-4976	272	7	t.	t.	NOUN
dpc-4976	272	8	th17	th17	PROPN
dpc-4976	272	9	cells	cell	NOUN
dpc-4976	272	10	and	and	CCONJ
dpc-4976	272	11	the	the	DET
dpc-4976	272	12	il-23	il-23	NOUN
dpc-4976	272	13	/	/	SYM
dpc-4976	272	14	il-17	il-17	NUM
dpc-4976	272	15	axis	axis	NOUN
dpc-4976	272	16	in	in	ADP
dpc-4976	272	17	the	the	DET
dpc-4976	272	18	pathogenesis	pathogenesis	NOUN
dpc-4976	272	19	of	of	ADP
dpc-4976	272	20	periodontitis	periodontitis	NOUN
dpc-4976	272	21	and	and	CCONJ
dpc-4976	272	22	immune	immune	NOUN
dpc-4976	272	23	-	-	PUNCT
dpc-4976	272	24	mediated	mediate	VERB
dpc-4976	272	25	inflammatory	inflammatory	ADJ
dpc-4976	272	26	diseases	disease	NOUN
dpc-4976	272	27	.	.	PUNCT
dpc-4976	273	1	int	int	PROPN
dpc-4976	273	2	j	j	PROPN
dpc-4976	273	3	mol	mol	ADP
dpc-4976	273	4	sci	sci	PROPN
dpc-4976	273	5	.	.	PUNCT
dpc-4976	273	6	2019;20(14	2019;20(14	NUM
dpc-4976	273	7	)	)	PUNCT
dpc-4976	273	8	.	.	PUNCT
dpc-4976	274	1	doi	doi	NOUN
dpc-4976	274	2	:	:	PUNCT
dpc-4976	274	3	10.3390	10.3390	NUM
dpc-4976	274	4	/	/	SYM
dpc-4976	274	5	ijms	ijm	VERB
dpc-4976	274	6	20143394	20143394	NUM
dpc-4976	274	7	.	.	PUNCT
dpc-4976	275	1	7	7	X
dpc-4976	275	2	.	.	X
dpc-4976	275	3	gargiulo	gargiulo	PROPN
dpc-4976	275	4	l	l	PROPN
dpc-4976	275	5	,	,	PUNCT
dpc-4976	275	6	narcisi	narcisi	ADV
dpc-4976	275	7	a	a	DET
dpc-4976	275	8	,	,	PUNCT
dpc-4976	275	9	ibba	ibba	ADJ
dpc-4976	275	10	l	l	NOUN
dpc-4976	275	11	,	,	PUNCT
dpc-4976	275	12	et	et	PROPN
dpc-4976	275	13	al	al	PROPN
dpc-4976	275	14	.	.	PROPN
dpc-4976	275	15	effectiveness	effectiveness	NOUN
dpc-4976	275	16	and	and	CCONJ
dpc-4976	275	17	safety	safety	NOUN
dpc-4976	275	18	of	of	ADP
dpc-4976	275	19	bimekizumab	bimekizumab	NOUN
dpc-4976	275	20	for	for	ADP
dpc-4976	275	21	the	the	DET
dpc-4976	275	22	treatment	treatment	NOUN
dpc-4976	275	23	of	of	ADP
dpc-4976	275	24	plaque	plaque	NOUN
dpc-4976	275	25	psoriasis	psoriasis	NOUN
dpc-4976	275	26	:	:	PUNCT
dpc-4976	275	27	a	a	DET
dpc-4976	275	28	real	real	ADJ
dpc-4976	275	29	-	-	PUNCT
dpc-4976	275	30	life	life	NOUN
dpc-4976	275	31	multicenter	multicenter	NOUN
dpc-4976	275	32	study	study	NOUN
dpc-4976	275	33	—	—	PUNCT
dpc-4976	275	34	il	il	PROPN
dpc-4976	275	35	pso	pso	NOUN
dpc-4976	275	36	(	(	PUNCT
dpc-4976	275	37	italian	italian	ADJ
dpc-4976	275	38	landscape	landscape	NOUN
dpc-4976	275	39	psoriasis	psoriasis	NOUN
dpc-4976	275	40	)	)	PUNCT
dpc-4976	275	41	.	.	PUNCT
dpc-4976	276	1	front	front	PROPN
dpc-4976	276	2	med	med	PROPN
dpc-4976	276	3	(	(	PUNCT
dpc-4976	276	4	lausanne	lausanne	PROPN
dpc-4976	276	5	)	)	PUNCT
dpc-4976	276	6	.	.	PUNCT
dpc-4976	277	1	2023;10	2023;10	NOUN
dpc-4976	277	2	.	.	PUNCT
dpc-4976	278	1	doi	doi	NOUN
dpc-4976	278	2	:	:	PUNCT
dpc-4976	278	3	10.3389	10.3389	NUM
dpc-4976	278	4	/	/	SYM
dpc-4976	278	5	fmed.2023.1243843	fmed.2023.1243843	NOUN
dpc-4976	278	6	.	.	NOUN
dpc-4976	278	7	8	8	NUM
dpc-4976	278	8	.	.	PUNCT
dpc-4976	279	1	warzyszak	warzyszak	PROPN
dpc-4976	279	2	p	p	NOUN
dpc-4976	279	3	,	,	PUNCT
dpc-4976	279	4	małek	małek	ADJ
dpc-4976	279	5	r	r	PROPN
dpc-4976	279	6	,	,	PUNCT
dpc-4976	279	7	milezek	milezek	PROPN
dpc-4976	279	8	m	m	PROPN
dpc-4976	279	9	,	,	PUNCT
dpc-4976	279	10	et	et	PROPN
dpc-4976	279	11	al	al	PROPN
dpc-4976	279	12	.	.	PUNCT
dpc-4976	280	1	psoriasis	psoriasis	VERB
dpc-4976	280	2	a	a	DET
dpc-4976	280	3	review	review	NOUN
dpc-4976	280	4	of	of	ADP
dpc-4976	280	5	recent	recent	ADJ
dpc-4976	280	6	progress	progress	NOUN
dpc-4976	280	7	,	,	PUNCT
dpc-4976	280	8	characteristics	characteristic	NOUN
dpc-4976	280	9	,	,	PUNCT
dpc-4976	280	10	diagnostic	diagnostic	ADJ
dpc-4976	280	11	management	management	NOUN
dpc-4976	280	12	.	.	PUNCT
dpc-4976	281	1	j	j	PROPN
dpc-4976	281	2	educ	educ	PROPN
dpc-4976	281	3	health	health	PROPN
dpc-4976	281	4	sport	sport	NOUN
dpc-4976	281	5	.	.	PUNCT
dpc-4976	282	1	2022;13(2):149–155	2022;13(2):149–155	X
dpc-4976	282	2	.	.	PUNCT
dpc-4976	282	3	doi	doi	NOUN
dpc-4976	282	4	:	:	PUNCT
dpc-4976	282	5	10.12775	10.12775	NUM
dpc-4976	282	6	/	/	SYM
dpc-4976	282	7	jehs	jehs	NOUN
dpc-4976	282	8	.2023.13.02.021	.2023.13.02.021	PUNCT
dpc-4976	282	9	.	.	PUNCT
dpc-4976	283	1	9	9	X
dpc-4976	283	2	.	.	X
dpc-4976	283	3	bhatt	bhatt	PROPN
dpc-4976	283	4	tj	tj	PROPN
dpc-4976	283	5	,	,	PUNCT
dpc-4976	283	6	sanghavi	sanghavi	VERB
dpc-4976	283	7	ur	ur	PROPN
dpc-4976	283	8	,	,	PUNCT
dpc-4976	283	9	zaveri	zaveri	PROPN
dpc-4976	283	10	zh	zh	PROPN
dpc-4976	283	11	.	.	PUNCT
dpc-4976	284	1	psoriasis	psoriasis	NOUN
dpc-4976	284	2	:	:	PUNCT
dpc-4976	284	3	a	a	DET
dpc-4976	284	4	peer	peer	NOUN
dpc-4976	284	5	review	review	NOUN
dpc-4976	284	6	article	article	NOUN
dpc-4976	284	7	.	.	PUNCT
dpc-4976	285	1	[	[	X
dpc-4976	285	2	www.ijfmr.com](https://www.ijfmr.com	www.ijfmr.com](https://www.ijfmr.com	X
dpc-4976	285	3	)	)	PUNCT
dpc-4976	285	4	.	.	PUNCT
dpc-4976	286	1	10	10	NUM
dpc-4976	286	2	.	.	PUNCT
dpc-4976	286	3	dasari	dasari	PROPN
dpc-4976	286	4	s	s	PROPN
dpc-4976	286	5	,	,	PUNCT
dpc-4976	286	6	choudhary	choudhary	PROPN
dpc-4976	286	7	a	a	X
dpc-4976	286	8	,	,	PUNCT
dpc-4976	286	9	madke	madke	ADJ
dpc-4976	286	10	b.	b.	NOUN
dpc-4976	286	11	psoriasis	psoriasis	NOUN
dpc-4976	286	12	:	:	PUNCT
dpc-4976	286	13	a	a	DET
dpc-4976	286	14	primer	primer	NOUN
dpc-4976	286	15	for	for	ADP
dpc-4976	286	16	general	general	ADJ
dpc-4976	286	17	physicians	physician	NOUN
dpc-4976	286	18	.	.	PUNCT
dpc-4976	287	1	cureus	cureus	NOUN
dpc-4976	287	2	.	.	PUNCT
dpc-4976	288	1	published	publish	VERB
dpc-4976	288	2	online	online	ADJ
dpc-4976	288	3	april	april	PROPN
dpc-4976	288	4	24	24	NUM
dpc-4976	288	5	,	,	PUNCT
dpc-4976	288	6	2023	2023	NUM
dpc-4976	288	7	.	.	PUNCT
dpc-4976	289	1	doi	doi	NOUN
dpc-4976	289	2	:	:	PUNCT
dpc-4976	289	3	10.7759	10.7759	NUM
dpc-4976	289	4	/cureus.38037	/cureus.38037	SYM
dpc-4976	289	5	.	.	PUNCT
dpc-4976	290	1	11	11	NUM
dpc-4976	290	2	.	.	X
dpc-4976	290	3	camiña	camiña	PROPN
dpc-4976	290	4	-	-	PUNCT
dpc-4976	290	5	conforto	conforto	PROPN
dpc-4976	290	6	g	g	PROPN
dpc-4976	290	7	,	,	PUNCT
dpc-4976	290	8	mateu	mateu	NOUN
dpc-4976	290	9	-	-	PUNCT
dpc-4976	290	10	arrom	arrom	NOUN
dpc-4976	290	11	l	l	NOUN
dpc-4976	290	12	,	,	PUNCT
dpc-4976	290	13	lópez	lópez	PROPN
dpc-4976	290	14	-	-	PUNCT
dpc-4976	290	15	ferrer	ferrer	PROPN
dpc-4976	290	16	a	a	PROPN
dpc-4976	290	17	,	,	PUNCT
dpc-4976	290	18	puig	puig	PROPN
dpc-4976	290	19	l.	l.	PROPN
dpc-4976	290	20	bimekizumab	bimekizumab	PROPN
dpc-4976	290	21	in	in	ADP
dpc-4976	290	22	the	the	DET
dpc-4976	290	23	treatment	treatment	NOUN
dpc-4976	290	24	of	of	ADP
dpc-4976	290	25	plaque	plaque	NOUN
dpc-4976	290	26	psoriasis	psoriasis	NOUN
dpc-4976	290	27	:	:	PUNCT
dpc-4976	290	28	focus	focus	VERB
dpc-4976	290	29	on	on	ADP
dpc-4976	290	30	patient	patient	ADJ
dpc-4976	290	31	selection	selection	NOUN
dpc-4976	290	32	and	and	CCONJ
dpc-4976	290	33	perspectives	perspective	NOUN
dpc-4976	290	34	.	.	PUNCT
dpc-4976	291	1	patient	patient	ADJ
dpc-4976	291	2	prefer	prefer	NOUN
dpc-4976	291	3	adherence	adherence	NOUN
dpc-4976	291	4	.	.	PUNCT
dpc-4976	292	1	2023;17:1541–1549	2023;17:1541–1549	NOUN
dpc-4976	292	2	.	.	PUNCT
dpc-4976	292	3	doi	doi	NOUN
dpc-4976	292	4	:	:	PUNCT
dpc-4976	292	5	10.2147	10.2147	NUM
dpc-4976	292	6	/	/	SYM
dpc-4976	292	7	ppa.s350760	ppa.s350760	NOUN
dpc-4976	292	8	.	.	PUNCT
dpc-4976	293	1	12	12	NUM
dpc-4976	293	2	.	.	PUNCT
dpc-4976	294	1	mahmoud	mahmoud	PROPN
dpc-4976	294	2	am	am	PROPN
dpc-4976	294	3	.	.	PUNCT
dpc-4976	295	1	meta	meta	ADJ
dpc-4976	295	2	-	-	PUNCT
dpc-4976	295	3	analysis	analysis	NOUN
dpc-4976	295	4	and	and	CCONJ
dpc-4976	295	5	grade	grade	NOUN
dpc-4976	295	6	assessment	assessment	NOUN
dpc-4976	295	7	of	of	ADP
dpc-4976	295	8	randomized	randomized	ADJ
dpc-4976	295	9	controlled	control	VERB
dpc-4976	295	10	trials	trial	NOUN
dpc-4976	295	11	on	on	ADP
dpc-4976	295	12	the	the	DET
dpc-4976	295	13	efficacy	efficacy	NOUN
dpc-4976	295	14	and	and	CCONJ
dpc-4976	295	15	safety	safety	NOUN
dpc-4976	295	16	of	of	ADP
dpc-4976	295	17	bimekizumab	bimekizumab	NOUN
dpc-4976	295	18	in	in	ADP
dpc-4976	295	19	psoriatic	psoriatic	ADJ
dpc-4976	295	20	arthritis	arthritis	NOUN
dpc-4976	295	21	patients	patient	NOUN
dpc-4976	295	22	.	.	PUNCT
dpc-4976	296	1	curr	curr	PROPN
dpc-4976	296	2	med	med	PROPN
dpc-4976	296	3	res	re	NOUN
dpc-4976	296	4	opin	opin	NOUN
dpc-4976	296	5	.	.	PUNCT
dpc-4976	297	1	2023;39(7	2023;39(7	NUM
dpc-4976	297	2	):	):	PUNCT
dpc-4976	297	3	1031–1043	1031–1043	NUM
dpc-4976	297	4	.	.	PUNCT
dpc-4976	298	1	doi	doi	NOUN
dpc-4976	298	2	:	:	PUNCT
dpc-4976	298	3	10.1080/03007995.2023.2228613	10.1080/03007995.2023.2228613	NUM
dpc-4976	298	4	.	.	X
dpc-4976	298	5	13	13	NUM
dpc-4976	298	6	.	.	X
dpc-4976	299	1	ruggiero	ruggiero	PROPN
dpc-4976	299	2	a	a	DET
dpc-4976	299	3	,	,	PUNCT
dpc-4976	299	4	potestio	potestio	NOUN
dpc-4976	299	5	l	l	NOUN
dpc-4976	299	6	,	,	PUNCT
dpc-4976	299	7	martora	martora	PROPN
dpc-4976	299	8	f	f	X
dpc-4976	299	9	,	,	PUNCT
dpc-4976	299	10	villani	villani	PROPN
dpc-4976	299	11	a	a	PROPN
dpc-4976	299	12	,	,	PUNCT
dpc-4976	299	13	comune	comune	PROPN
dpc-4976	299	14	r	r	NOUN
dpc-4976	299	15	,	,	PUNCT
dpc-4976	299	16	megna	megna	PROPN
dpc-4976	299	17	m.	m.	PROPN
dpc-4976	299	18	bimekizumab	bimekizumab	PROPN
dpc-4976	299	19	treatment	treatment	NOUN
dpc-4976	299	20	in	in	ADP
dpc-4976	299	21	patients	patient	NOUN
dpc-4976	299	22	with	with	ADP
dpc-4976	299	23	moderate	moderate	ADJ
dpc-4976	299	24	to	to	ADP
dpc-4976	299	25	severe	severe	ADJ
dpc-4976	299	26	plaque	plaque	NOUN
dpc-4976	299	27	psoriasis	psoriasis	NOUN
dpc-4976	299	28	:	:	PUNCT
dpc-4976	299	29	a	a	DET
dpc-4976	299	30	drug	drug	NOUN
dpc-4976	299	31	safety	safety	NOUN
dpc-4976	299	32	evaluation	evaluation	NOUN
dpc-4976	299	33	.	.	PUNCT
dpc-4976	300	1	expert	expert	NOUN
dpc-4976	300	2	opin	opin	NOUN
dpc-4976	300	3	drug	drug	NOUN
dpc-4976	300	4	saf	saf	PROPN
dpc-4976	300	5	.	.	PROPN
dpc-4976	300	6	2023;22(5):355–362	2023;22(5):355–362	NUM
dpc-4976	300	7	.	.	PUNCT
dpc-4976	301	1	doi	doi	NOUN
dpc-4976	301	2	:	:	PUNCT
dpc-4976	301	3	10.1080/14740338.2023.2218086	10.1080/14740338.2023.2218086	NUM
dpc-4976	301	4	.	.	PUNCT
dpc-4976	302	1	14	14	NUM
dpc-4976	302	2	.	.	PUNCT
dpc-4976	303	1	gordon	gordon	PROPN
dpc-4976	303	2	kb	kb	PROPN
dpc-4976	303	3	,	,	PUNCT
dpc-4976	303	4	foley	foley	PROPN
dpc-4976	303	5	p	p	PROPN
dpc-4976	303	6	,	,	PUNCT
dpc-4976	303	7	krueger	krueger	PROPN
dpc-4976	303	8	jg	jg	PROPN
dpc-4976	303	9	,	,	PUNCT
dpc-4976	303	10	et	et	PROPN
dpc-4976	303	11	al	al	PROPN
dpc-4976	303	12	.	.	PROPN
dpc-4976	303	13	bimekizumab	bimekizumab	PROPN
dpc-4976	303	14	efficacy	efficacy	PROPN
dpc-4976	303	15	and	and	CCONJ
dpc-4976	303	16	safety	safety	NOUN
dpc-4976	303	17	in	in	ADP
dpc-4976	303	18	moderate	moderate	ADJ
dpc-4976	303	19	to	to	ADP
dpc-4976	303	20	severe	severe	ADJ
dpc-4976	303	21	plaque	plaque	NOUN
dpc-4976	303	22	psoriasis	psoriasis	NOUN
dpc-4976	303	23	(	(	PUNCT
dpc-4976	303	24	be	be	AUX
dpc-4976	303	25	ready	ready	ADJ
dpc-4976	303	26	):	):	PUNCT