id sid tid token lemma pos dpc-5888 1 1 dermatology dermatology NOUN dpc-5888 1 2 : : PUNCT dpc-5888 1 3 practical practical ADJ dpc-5888 1 4 and and CCONJ dpc-5888 1 5 conceptual conceptual ADJ dpc-5888 1 6 image image NOUN dpc-5888 1 7 letter letter NOUN dpc-5888 2 1 | | ADV dpc-5888 2 2 dermatol dermatol ADJ dpc-5888 2 3 pract pract NOUN dpc-5888 2 4 concept concept NOUN dpc-5888 2 5 . . PUNCT dpc-5888 3 1 2025;15(4):5888 2025;15(4):5888 NUM dpc-5888 3 2 1 1 NUM dpc-5888 3 3 hutchinson hutchinson PROPN dpc-5888 3 4 ’s ’s PART dpc-5888 3 5 sign sign NOUN dpc-5888 3 6 without without ADP dpc-5888 3 7 melanonychia melanonychia PROPN dpc-5888 3 8 : : PUNCT dpc-5888 3 9 a a DET dpc-5888 3 10 key key NOUN dpc-5888 3 11 for for ADP dpc-5888 3 12 the the DET dpc-5888 3 13 diagnosis diagnosis NOUN dpc-5888 3 14 of of ADP dpc-5888 3 15 invasive invasive ADJ dpc-5888 3 16 melanoma melanoma NOUN dpc-5888 3 17 of of ADP dpc-5888 3 18 the the DET dpc-5888 3 19 nail nail NOUN dpc-5888 3 20 matrix matrix NOUN dpc-5888 3 21 alejandra alejandra PROPN dpc-5888 3 22 jaramillo jaramillo PROPN dpc-5888 3 23 - - PUNCT dpc-5888 3 24 arboleda1,2 arboleda1,2 PROPN dpc-5888 3 25 , , PUNCT dpc-5888 3 26 maría maría PROPN dpc-5888 3 27 fernanda fernanda PROPN dpc-5888 3 28 torres torres PROPN dpc-5888 3 29 - - PUNCT dpc-5888 3 30 calderón1,3 calderón1,3 PROPN dpc-5888 3 31 , , PUNCT dpc-5888 3 32 francesco francesco PROPN dpc-5888 3 33 piscazzi1,4,5 piscazzi1,4,5 VERB dpc-5888 3 34 , , PUNCT dpc-5888 3 35 maria maria PROPN dpc-5888 3 36 paz paz PROPN dpc-5888 3 37 micieli micieli PROPN dpc-5888 3 38 galeazzi1,6 galeazzi1,6 PROPN dpc-5888 3 39 , , PUNCT dpc-5888 3 40 llucia llucia PROPN dpc-5888 3 41 alos1 alos1 PROPN dpc-5888 3 42 , , PUNCT dpc-5888 3 43 susana susana PROPN dpc-5888 3 44 puig puig PROPN dpc-5888 3 45 sardà1,7 sardà1,7 PROPN dpc-5888 3 46 1 1 NUM dpc-5888 3 47 hospital hospital NOUN dpc-5888 3 48 clínic clínic PROPN dpc-5888 3 49 de de PROPN dpc-5888 3 50 barcelona barcelona PROPN dpc-5888 3 51 , , PUNCT dpc-5888 3 52 universitat universitat PROPN dpc-5888 3 53 de de PROPN dpc-5888 3 54 barcelona barcelona PROPN dpc-5888 3 55 , , PUNCT dpc-5888 3 56 institut institut PROPN dpc-5888 3 57 d’investigacions d’investigacions PROPN dpc-5888 3 58 biomediques biomedique VERB dpc-5888 3 59 august august PROPN dpc-5888 3 60 pi pi NOUN dpc-5888 4 1 i i PRON dpc-5888 4 2 sunyer sunyer NOUN dpc-5888 4 3 ( ( PUNCT dpc-5888 4 4 idibaps idibap NOUN dpc-5888 4 5 ) ) PUNCT dpc-5888 4 6 , , PUNCT dpc-5888 4 7 barcelona barcelona PROPN dpc-5888 4 8 , , PUNCT dpc-5888 4 9 spain spain PROPN dpc-5888 4 10 2 2 NUM dpc-5888 4 11 department department NOUN dpc-5888 4 12 of of ADP dpc-5888 4 13 dermatology dermatology NOUN dpc-5888 4 14 , , PUNCT dpc-5888 4 15 el el PROPN dpc-5888 4 16 bosque bosque PROPN dpc-5888 4 17 university university PROPN dpc-5888 4 18 simon simon PROPN dpc-5888 4 19 bolivar bolivar PROPN dpc-5888 4 20 hospital hospital PROPN dpc-5888 4 21 , , PUNCT dpc-5888 4 22 bogotá bogotá NOUN dpc-5888 4 23 , , PUNCT dpc-5888 4 24 colombia colombia PROPN dpc-5888 4 25 3 3 NUM dpc-5888 4 26 department department NOUN dpc-5888 4 27 of of ADP dpc-5888 4 28 dermatology dermatology NOUN dpc-5888 4 29 , , PUNCT dpc-5888 4 30 instituto instituto PROPN dpc-5888 4 31 dermatológico dermatológico PROPN dpc-5888 4 32 de de PROPN dpc-5888 4 33 jalisco jalisco PROPN dpc-5888 4 34 “ " PUNCT dpc-5888 4 35 dr dr PROPN dpc-5888 4 36 . . PROPN dpc-5888 4 37 josé josé PROPN dpc-5888 4 38 barba barba PROPN dpc-5888 4 39 rubio rubio PROPN dpc-5888 4 40 ” " PUNCT dpc-5888 4 41 , , PUNCT dpc-5888 4 42 jalisco jalisco PROPN dpc-5888 4 43 , , PUNCT dpc-5888 4 44 mexico mexico PROPN dpc-5888 4 45 4 4 NUM dpc-5888 4 46 dermatology dermatology NOUN dpc-5888 4 47 unit unit NOUN dpc-5888 4 48 , , PUNCT dpc-5888 4 49 irccs ircc VERB dpc-5888 4 50 humanitas humanitas NOUN dpc-5888 4 51 research research NOUN dpc-5888 4 52 hospital hospital NOUN dpc-5888 4 53 , , PUNCT dpc-5888 4 54 rozzano rozzano PROPN dpc-5888 4 55 , , PUNCT dpc-5888 4 56 milano milano PROPN dpc-5888 4 57 , , PUNCT dpc-5888 4 58 italy italy PROPN dpc-5888 4 59 5 5 NUM dpc-5888 4 60 department department PROPN dpc-5888 4 61 of of ADP dpc-5888 4 62 biomedical biomedical ADJ dpc-5888 4 63 sciences sciences PROPN dpc-5888 4 64 , , PUNCT dpc-5888 4 65 humanitas humanita NOUN dpc-5888 4 66 university university NOUN dpc-5888 4 67 , , PUNCT dpc-5888 4 68 pieve pieve PROPN dpc-5888 4 69 emanuele emanuele PROPN dpc-5888 4 70 , , PUNCT dpc-5888 4 71 milano milano PROPN dpc-5888 4 72 , , PUNCT dpc-5888 4 73 italy italy PROPN dpc-5888 4 74 6 6 NUM dpc-5888 4 75 dermatology dermatology NOUN dpc-5888 4 76 service service NOUN dpc-5888 4 77 , , PUNCT dpc-5888 4 78 italian italian ADJ dpc-5888 4 79 hospital hospital NOUN dpc-5888 4 80 of of ADP dpc-5888 4 81 buenos buenos PROPN dpc-5888 4 82 aires aires PROPN dpc-5888 4 83 , , PUNCT dpc-5888 4 84 autonomous autonomous ADJ dpc-5888 4 85 city city NOUN dpc-5888 4 86 of of ADP dpc-5888 4 87 buenos buenos PROPN dpc-5888 4 88 aires aires PROPN dpc-5888 4 89 , , PUNCT dpc-5888 4 90 argentina argentina PROPN dpc-5888 4 91 7 7 NUM dpc-5888 4 92 centro centro X dpc-5888 4 93 de de PROPN dpc-5888 4 94 investigación investigación PROPN dpc-5888 4 95 biomèdica biomèdica PROPN dpc-5888 4 96 en en PROPN dpc-5888 4 97 red red PROPN dpc-5888 4 98 de de PROPN dpc-5888 4 99 enfermedades enfermedades PROPN dpc-5888 4 100 raras raras NOUN dpc-5888 4 101 ( ( PUNCT dpc-5888 4 102 ciberer ciberer NOUN dpc-5888 4 103 ) ) PUNCT dpc-5888 4 104 , , PUNCT dpc-5888 4 105 instituto instituto PROPN dpc-5888 4 106 de de PROPN dpc-5888 4 107 salud salud PROPN dpc-5888 4 108 carlos carlos PROPN dpc-5888 4 109 iii iii PROPN dpc-5888 4 110 , , PUNCT dpc-5888 4 111 barcelona barcelona PROPN dpc-5888 4 112 , , PUNCT dpc-5888 4 113 spain spain PROPN dpc-5888 4 114 key key ADJ dpc-5888 4 115 words word NOUN dpc-5888 4 116 : : PUNCT dpc-5888 4 117 hutchinson hutchinson PROPN dpc-5888 4 118 sign sign PROPN dpc-5888 4 119 , , PUNCT dpc-5888 4 120 nail nail NOUN dpc-5888 4 121 matrix matrix NOUN dpc-5888 4 122 melanoma melanoma NOUN dpc-5888 4 123 , , PUNCT dpc-5888 4 124 dermoscopy dermoscopy NOUN dpc-5888 4 125 , , PUNCT dpc-5888 4 126 confocal confocal ADJ dpc-5888 4 127 microscopy microscopy NOUN dpc-5888 4 128 citation citation NOUN dpc-5888 4 129 : : PUNCT dpc-5888 4 130 jaramillo jaramillo NOUN dpc-5888 4 131 - - PUNCT dpc-5888 4 132 arboleda arboleda NOUN dpc-5888 4 133 a a PRON dpc-5888 4 134 , , PUNCT dpc-5888 4 135 torres torre NOUN dpc-5888 4 136 - - PUNCT dpc-5888 4 137 calderón calderón NOUN dpc-5888 4 138 mf mf NOUN dpc-5888 4 139 , , PUNCT dpc-5888 4 140 piscazzi piscazzi NOUN dpc-5888 4 141 f f NOUN dpc-5888 4 142 , , PUNCT dpc-5888 4 143 micieli micieli PROPN dpc-5888 4 144 galeazzi galeazzi PROPN dpc-5888 4 145 mp mp PROPN dpc-5888 4 146 , , PUNCT dpc-5888 4 147 alos alos PROPN dpc-5888 4 148 l l PROPN dpc-5888 4 149 , , PUNCT dpc-5888 4 150 puig puig PROPN dpc-5888 4 151 s. s. PROPN dpc-5888 4 152 hutchinson hutchinson PROPN dpc-5888 4 153 ’s ’s PART dpc-5888 4 154 sign sign NOUN dpc-5888 4 155 without without ADP dpc-5888 4 156 melanonychia melanonychia PROPN dpc-5888 4 157 : : PUNCT dpc-5888 4 158 a a DET dpc-5888 4 159 key key NOUN dpc-5888 4 160 for for ADP dpc-5888 4 161 the the DET dpc-5888 4 162 diagnosis diagnosis NOUN dpc-5888 4 163 of of ADP dpc-5888 4 164 invasive invasive ADJ dpc-5888 4 165 melanoma melanoma NOUN dpc-5888 4 166 of of ADP dpc-5888 4 167 the the DET dpc-5888 4 168 nail nail NOUN dpc-5888 4 169 matrix matrix NOUN dpc-5888 4 170 . . PUNCT dpc-5888 5 1 dermatol dermatol NOUN dpc-5888 5 2 pract pract PROPN dpc-5888 5 3 concept concept NOUN dpc-5888 5 4 . . PUNCT dpc-5888 6 1 2025;15(4):5888 2025;15(4):5888 NUM dpc-5888 6 2 . . PUNCT dpc-5888 6 3 doi doi PROPN dpc-5888 6 4 : : PUNCT dpc-5888 6 5 https://doi.org/10.5826/dpc.1504a5888 https://doi.org/10.5826/dpc.1504a5888 X dpc-5888 6 6 accepted accept VERB dpc-5888 6 7 : : PUNCT dpc-5888 6 8 april april PROPN dpc-5888 6 9 17 17 NUM dpc-5888 6 10 , , PUNCT dpc-5888 6 11 2025 2025 NUM dpc-5888 6 12 ; ; PUNCT dpc-5888 6 13 published publish VERB dpc-5888 6 14 : : PUNCT dpc-5888 7 1 october october PROPN dpc-5888 7 2 2025 2025 NUM dpc-5888 7 3 copyright copyright NOUN dpc-5888 7 4 : : PUNCT dpc-5888 7 5 © © PROPN dpc-5888 7 6 2025 2025 NUM dpc-5888 7 7 jaramillo jaramillo NOUN dpc-5888 7 8 - - PUNCT dpc-5888 7 9 arboleda arboleda NOUN dpc-5888 7 10 et et PROPN dpc-5888 7 11 al al PROPN dpc-5888 7 12 . . PUNCT dpc-5888 8 1 this this PRON dpc-5888 8 2 is be AUX dpc-5888 8 3 an an DET dpc-5888 8 4 open open ADJ dpc-5888 8 5 - - PUNCT dpc-5888 8 6 access access NOUN dpc-5888 8 7 article article NOUN dpc-5888 8 8 distributed distribute VERB dpc-5888 8 9 under under ADP dpc-5888 8 10 the the DET dpc-5888 8 11 terms term NOUN dpc-5888 8 12 of of ADP dpc-5888 8 13 the the DET dpc-5888 8 14 creative creative ADJ dpc-5888 8 15 commons common NOUN dpc-5888 8 16 attribution attribution NOUN dpc-5888 8 17 - - PUNCT dpc-5888 8 18 noncommercial noncommercial ADJ dpc-5888 8 19 license license NOUN dpc-5888 8 20 ( ( PUNCT dpc-5888 8 21 by by ADP dpc-5888 8 22 - - PUNCT dpc-5888 8 23 nc-4.0 nc-4.0 NOUN dpc-5888 8 24 ) ) PUNCT dpc-5888 8 25 , , PUNCT dpc-5888 8 26 https://creativecommons.org/licenses/by-nc/4.0/ https://creativecommons.org/licenses/by-nc/4.0/ PROPN dpc-5888 8 27 , , PUNCT dpc-5888 8 28 which which PRON dpc-5888 8 29 permits permit VERB dpc-5888 8 30 unrestricted unrestricted ADJ dpc-5888 8 31 noncommercial noncommercial ADJ dpc-5888 8 32 use use NOUN dpc-5888 8 33 , , PUNCT dpc-5888 8 34 distribution distribution NOUN dpc-5888 8 35 , , PUNCT dpc-5888 8 36 and and CCONJ dpc-5888 8 37 reproduction reproduction NOUN dpc-5888 8 38 in in ADP dpc-5888 8 39 any any DET dpc-5888 8 40 medium medium NOUN dpc-5888 8 41 , , PUNCT dpc-5888 8 42 provided provide VERB dpc-5888 8 43 the the DET dpc-5888 8 44 original original ADJ dpc-5888 8 45 authors author NOUN dpc-5888 8 46 and and CCONJ dpc-5888 8 47 source source NOUN dpc-5888 8 48 are be AUX dpc-5888 8 49 credited credit VERB dpc-5888 8 50 . . PUNCT dpc-5888 9 1 funding funding NOUN dpc-5888 9 2 : : PUNCT dpc-5888 9 3 none none NOUN dpc-5888 9 4 . . PUNCT dpc-5888 10 1 competing compete VERB dpc-5888 10 2 interests interest NOUN dpc-5888 10 3 : : PUNCT dpc-5888 10 4 none none NOUN dpc-5888 10 5 . . PUNCT dpc-5888 11 1 authorship authorship NOUN dpc-5888 11 2 : : PUNCT dpc-5888 11 3 all all DET dpc-5888 11 4 authors author NOUN dpc-5888 11 5 have have AUX dpc-5888 11 6 contributed contribute VERB dpc-5888 11 7 significantly significantly ADV dpc-5888 11 8 to to ADP dpc-5888 11 9 this this DET dpc-5888 11 10 publication publication NOUN dpc-5888 11 11 . . PUNCT dpc-5888 12 1 corresponding correspond VERB dpc-5888 12 2 author author NOUN dpc-5888 12 3 : : PUNCT dpc-5888 12 4 susana susana PROPN dpc-5888 12 5 puig puig PROPN dpc-5888 12 6 , , PUNCT dpc-5888 12 7 hospital hospital NOUN dpc-5888 12 8 clínic clínic PROPN dpc-5888 12 9 de de PROPN dpc-5888 12 10 barcelona barcelona PROPN dpc-5888 12 11 , , PUNCT dpc-5888 12 12 universitat universitat PROPN dpc-5888 12 13 de de PROPN dpc-5888 12 14 barcelona barcelona PROPN dpc-5888 12 15 , , PUNCT dpc-5888 12 16 institut institut PROPN dpc-5888 12 17 d’investigacions d’investigacions PROPN dpc-5888 12 18 biomediques biomedique VERB dpc-5888 12 19 august august PROPN dpc-5888 12 20 pi pi NOUN dpc-5888 13 1 i i PRON dpc-5888 13 2 sunyer sunyer NOUN dpc-5888 13 3 ( ( PUNCT dpc-5888 13 4 idibaps idibap NOUN dpc-5888 13 5 ) ) PUNCT dpc-5888 13 6 , , PUNCT dpc-5888 13 7 carrer carrer PROPN dpc-5888 13 8 de de PROPN dpc-5888 13 9 villarroel villarroel PROPN dpc-5888 13 10 170 170 NUM dpc-5888 13 11 , , PUNCT dpc-5888 13 12 08036 08036 NUM dpc-5888 13 13 , , PUNCT dpc-5888 13 14 barcelona barcelona PROPN dpc-5888 13 15 , , PUNCT dpc-5888 13 16 spain spain PROPN dpc-5888 13 17 . . PUNCT dpc-5888 14 1 orcid orcid PROPN dpc-5888 15 1 i i PRON dpc-5888 15 2 d d NOUN dpc-5888 15 3 : : PUNCT dpc-5888 15 4 0000 0000 NUM dpc-5888 15 5 - - PUNCT dpc-5888 15 6 0003 0003 NUM dpc-5888 15 7 - - PUNCT dpc-5888 15 8 1337 1337 NUM dpc-5888 15 9 - - SYM dpc-5888 15 10 9745 9745 NUM dpc-5888 15 11 . . PUNCT dpc-5888 16 1 e e X dpc-5888 16 2 - - NOUN dpc-5888 16 3 mail mail NOUN dpc-5888 16 4 : : PUNCT dpc-5888 17 1 susipuig@gmail.com susipuig@gmail.com ADJ dpc-5888 17 2 ; ; PUNCT dpc-5888 17 3 spuig@clinic.cat spuig@clinic.cat NOUN dpc-5888 17 4 case case NOUN dpc-5888 17 5 presentation presentation NOUN dpc-5888 17 6 a a DET dpc-5888 17 7 70 70 NUM dpc-5888 17 8 - - PUNCT dpc-5888 17 9 year year NOUN dpc-5888 17 10 - - PUNCT dpc-5888 17 11 old old ADJ dpc-5888 17 12 male male NOUN dpc-5888 17 13 presented present VERB dpc-5888 17 14 with with ADP dpc-5888 17 15 a a DET dpc-5888 17 16 recently recently ADV dpc-5888 17 17 noticed notice VERB dpc-5888 17 18 pigmented pigmented ADJ dpc-5888 17 19 lesion lesion NOUN dpc-5888 17 20 on on ADP dpc-5888 17 21 the the DET dpc-5888 17 22 periungual periungual ADJ dpc-5888 17 23 region region NOUN dpc-5888 17 24 of of ADP dpc-5888 17 25 the the DET dpc-5888 17 26 fifth fifth ADJ dpc-5888 17 27 finger finger NOUN dpc-5888 17 28 of of ADP dpc-5888 17 29 his his PRON dpc-5888 17 30 right right ADJ dpc-5888 17 31 hand hand NOUN dpc-5888 17 32 . . PUNCT dpc-5888 18 1 clinical clinical ADJ dpc-5888 18 2 examination examination NOUN dpc-5888 18 3 revealed reveal VERB dpc-5888 18 4 a a DET dpc-5888 18 5 6 6 NUM dpc-5888 18 6 × × NOUN dpc-5888 18 7 4 4 NUM dpc-5888 18 8 mm mm NOUN dpc-5888 18 9 lesion lesion NOUN dpc-5888 18 10 on on ADP dpc-5888 18 11 the the DET dpc-5888 18 12 proximal proximal ADJ dpc-5888 18 13 and and CCONJ dpc-5888 18 14 lateral lateral ADJ dpc-5888 18 15 nailfolds nailfold NOUN dpc-5888 18 16 , , PUNCT dpc-5888 18 17 with with ADP dpc-5888 18 18 no no DET dpc-5888 18 19 melanonychia melanonychia NOUN dpc-5888 18 20 ( ( PUNCT dpc-5888 18 21 figure figure NOUN dpc-5888 18 22 1 1 NUM dpc-5888 18 23 ) ) PUNCT dpc-5888 18 24 . . PUNCT dpc-5888 19 1 dermoscopy dermoscopy NOUN dpc-5888 19 2 showed show VERB dpc-5888 19 3 irregular irregular ADJ dpc-5888 19 4 brown brown ADJ dpc-5888 19 5 pigmentation pigmentation NOUN dpc-5888 19 6 and and CCONJ dpc-5888 19 7 a a DET dpc-5888 19 8 parallel parallel ADJ dpc-5888 19 9 ridge ridge NOUN dpc-5888 19 10 pattern pattern NOUN dpc-5888 19 11 in in ADP dpc-5888 19 12 the the DET dpc-5888 19 13 volar volar ADJ dpc-5888 19 14 skin skin NOUN dpc-5888 19 15 . . PUNCT dpc-5888 20 1 reflectance reflectance NOUN dpc-5888 20 2 confocal confocal ADJ dpc-5888 20 3 microscopy microscopy NOUN dpc-5888 20 4 revealed reveal VERB dpc-5888 20 5 a a DET dpc-5888 20 6 regular regular ADJ dpc-5888 20 7 honeycomb honeycomb NOUN dpc-5888 20 8 pattern pattern NOUN dpc-5888 20 9 , , PUNCT dpc-5888 20 10 upper upper ADJ dpc-5888 20 11 epidermis epidermis NOUN dpc-5888 20 12 without without ADP dpc-5888 20 13 atypical atypical ADJ dpc-5888 20 14 cells cell NOUN dpc-5888 20 15 , , PUNCT dpc-5888 20 16 and and CCONJ dpc-5888 20 17 bright bright ADJ dpc-5888 20 18 melanocytes melanocyte NOUN dpc-5888 20 19 at at ADP dpc-5888 20 20 dermoepidermal dermoepidermal ADJ dpc-5888 20 21 junction junction NOUN dpc-5888 20 22 ( ( PUNCT dpc-5888 20 23 1–3 1–3 NOUN dpc-5888 20 24 per per ADP dpc-5888 20 25 dermal dermal ADJ dpc-5888 20 26 papilla papilla NOUN dpc-5888 20 27 ) ) PUNCT dpc-5888 20 28 . . PUNCT dpc-5888 21 1 initial initial ADJ dpc-5888 21 2 punch punch NOUN dpc-5888 21 3 biopsy biopsy NOUN dpc-5888 21 4 demonstrated demonstrate VERB dpc-5888 21 5 melanocytic melanocytic ADJ dpc-5888 21 6 hyperplasia hyperplasia NOUN dpc-5888 21 7 with with ADP dpc-5888 21 8 mild mild ADJ dpc-5888 21 9 atypia atypia NOUN dpc-5888 21 10 . . PUNCT dpc-5888 22 1 to to PART dpc-5888 22 2 rule rule VERB dpc-5888 22 3 out out ADP dpc-5888 22 4 matrix matrix NOUN dpc-5888 22 5 melanoma melanoma NOUN dpc-5888 22 6 , , PUNCT dpc-5888 22 7 nail nail NOUN dpc-5888 22 8 matrix matrix NOUN dpc-5888 22 9 biopsy biopsy NOUN dpc-5888 22 10 showed show VERB dpc-5888 22 11 extensive extensive ADJ dpc-5888 22 12 melanocytic melanocytic ADJ dpc-5888 22 13 hyperplasia hyperplasia NOUN dpc-5888 22 14 with with ADP dpc-5888 22 15 prame prame NOUN dpc-5888 22 16 positivity positivity NOUN dpc-5888 22 17 . . PUNCT dpc-5888 23 1 complete complete ADJ dpc-5888 23 2 matricectomy matricectomy NOUN dpc-5888 23 3 revealed reveal VERB dpc-5888 23 4 acral acral ADJ dpc-5888 23 5 lentiginous lentiginous ADJ dpc-5888 23 6 melanoma melanoma NOUN dpc-5888 23 7 with with ADP dpc-5888 23 8 a a DET dpc-5888 23 9 breslow breslow ADJ dpc-5888 23 10 thickness thickness NOUN dpc-5888 23 11 of of ADP dpc-5888 23 12 0.2 0.2 NUM dpc-5888 23 13 mm mm NOUN dpc-5888 23 14 . . PUNCT dpc-5888 24 1 therapeutic therapeutic ADJ dpc-5888 24 2 margin margin NOUN dpc-5888 24 3 widening widen VERB dpc-5888 24 4 surgery surgery NOUN dpc-5888 24 5 showed show VERB dpc-5888 24 6 no no DET dpc-5888 24 7 residual residual ADJ dpc-5888 24 8 neoplasia neoplasia NOUN dpc-5888 24 9 , , PUNCT dpc-5888 24 10 confirmed confirm VERB dpc-5888 24 11 by by ADP dpc-5888 24 12 sox10 sox10 PROPN dpc-5888 24 13 immunohistochemistry immunohistochemistry NOUN dpc-5888 24 14 . . PUNCT dpc-5888 25 1 teaching teaching NOUN dpc-5888 25 2 point point NOUN dpc-5888 25 3 subungual subungual ADJ dpc-5888 25 4 melanoma melanoma NOUN dpc-5888 25 5 is be AUX dpc-5888 25 6 a a DET dpc-5888 25 7 rare rare ADJ dpc-5888 25 8 condition condition NOUN dpc-5888 25 9 , , PUNCT dpc-5888 25 10 accounting account VERB dpc-5888 25 11 for for ADP dpc-5888 25 12 only only ADV dpc-5888 25 13 0.7 0.7 NUM dpc-5888 25 14 % % NOUN dpc-5888 25 15 to to PART dpc-5888 25 16 3.5 3.5 NUM dpc-5888 25 17 % % NOUN dpc-5888 25 18 of of ADP dpc-5888 25 19 melanoma melanoma NOUN dpc-5888 25 20 cases case NOUN dpc-5888 25 21 [ [ X dpc-5888 25 22 1 1 NUM dpc-5888 25 23 ] ] PUNCT dpc-5888 25 24 . . PUNCT dpc-5888 26 1 subungual subungual ADJ dpc-5888 26 2 melanoma melanoma NOUN dpc-5888 26 3 often often ADV dpc-5888 26 4 presents present VERB dpc-5888 26 5 with with ADP dpc-5888 26 6 a a DET dpc-5888 26 7 pigmented pigmented ADJ dpc-5888 26 8 brown brown ADJ dpc-5888 26 9 or or CCONJ dpc-5888 26 10 black black ADJ dpc-5888 26 11 longitudinal longitudinal ADJ dpc-5888 26 12 2 2 NUM dpc-5888 26 13 image image NOUN dpc-5888 26 14 letter letter NOUN dpc-5888 26 15 | | ADV dpc-5888 26 16 dermatol dermatol ADJ dpc-5888 26 17 pract pract NOUN dpc-5888 26 18 concept concept NOUN dpc-5888 26 19 . . PUNCT dpc-5888 27 1 2025;15(4):5888 2025;15(4):5888 NUM dpc-5888 27 2 figure figure NOUN dpc-5888 27 3 1 1 NUM dpc-5888 27 4 . . PUNCT dpc-5888 27 5 clinical clinical ADJ dpc-5888 27 6 examination examination NOUN dpc-5888 27 7 revealed reveal VERB dpc-5888 27 8 a a DET dpc-5888 27 9 pigmented pigmented ADJ dpc-5888 27 10 lesion lesion NOUN dpc-5888 27 11 on on ADP dpc-5888 27 12 the the DET dpc-5888 27 13 lateral lateral ADJ dpc-5888 27 14 nailfold nailfold NOUN dpc-5888 27 15 of of ADP dpc-5888 27 16 the the DET dpc-5888 27 17 fifth fifth ADJ dpc-5888 27 18 finger finger NOUN dpc-5888 27 19 of of ADP dpc-5888 27 20 the the DET dpc-5888 27 21 right right ADJ dpc-5888 27 22 hand hand NOUN dpc-5888 27 23 , , PUNCT dpc-5888 27 24 extending extend VERB dpc-5888 27 25 to to ADP dpc-5888 27 26 the the DET dpc-5888 27 27 periungual periungual ADJ dpc-5888 27 28 skin skin NOUN dpc-5888 27 29 , , PUNCT dpc-5888 27 30 with with ADP dpc-5888 27 31 no no DET dpc-5888 27 32 evidence evidence NOUN dpc-5888 27 33 of of ADP dpc-5888 27 34 melanonychia melanonychia PROPN dpc-5888 27 35 ( ( PUNCT dpc-5888 27 36 a a NOUN dpc-5888 27 37 ) ) PUNCT dpc-5888 27 38 . . PUNCT dpc-5888 28 1 dermoscopy dermoscopy NOUN dpc-5888 28 2 showed show VERB dpc-5888 28 3 irregular irregular ADJ dpc-5888 28 4 , , PUNCT dpc-5888 28 5 asymmetrical asymmetrical ADJ dpc-5888 28 6 brown brown ADJ dpc-5888 28 7 pigmentation pigmentation NOUN dpc-5888 28 8 radiating radiate VERB dpc-5888 28 9 into into ADP dpc-5888 28 10 the the DET dpc-5888 28 11 lateral lateral ADJ dpc-5888 28 12 nailfold nailfold NOUN dpc-5888 28 13 , , PUNCT dpc-5888 28 14 consistent consistent ADJ dpc-5888 28 15 with with ADP dpc-5888 28 16 hutchinson hutchinson PROPN dpc-5888 28 17 ’s ’s PART dpc-5888 28 18 sign sign NOUN dpc-5888 28 19 ( ( PUNCT dpc-5888 28 20 b b NOUN dpc-5888 28 21 ) ) PUNCT dpc-5888 28 22 . . PUNCT dpc-5888 29 1 reflectance reflectance NOUN dpc-5888 29 2 confocal confocal ADJ dpc-5888 29 3 microscopy microscopy NOUN dpc-5888 29 4 of of ADP dpc-5888 29 5 the the DET dpc-5888 29 6 previously previously ADV dpc-5888 29 7 biopsied biopsie VERB dpc-5888 29 8 periungual periungual ADJ dpc-5888 29 9 skin skin NOUN dpc-5888 29 10 demonstrated demonstrate VERB dpc-5888 29 11 the the DET dpc-5888 29 12 honeycomb honeycomb NOUN dpc-5888 29 13 pattern pattern NOUN dpc-5888 29 14 of of ADP dpc-5888 29 15 the the DET dpc-5888 29 16 epidermis epidermis NOUN dpc-5888 29 17 , , PUNCT dpc-5888 29 18 with with ADP dpc-5888 29 19 the the DET dpc-5888 29 20 focal focal ADJ dpc-5888 29 21 presence presence NOUN dpc-5888 29 22 of of ADP dpc-5888 29 23 shiny shiny ADJ dpc-5888 29 24 - - PUNCT dpc-5888 29 25 white white ADJ dpc-5888 29 26 pagetoid pagetoid NOUN dpc-5888 29 27 dendritic dendritic ADJ dpc-5888 29 28 cells cell NOUN dpc-5888 29 29 ( ( PUNCT dpc-5888 29 30 c c NOUN dpc-5888 29 31 ) ) PUNCT dpc-5888 29 32 and and CCONJ dpc-5888 29 33 irregular irregular ADJ dpc-5888 29 34 clusters cluster NOUN dpc-5888 29 35 of of ADP dpc-5888 29 36 bright bright ADJ dpc-5888 29 37 atypical atypical ADJ dpc-5888 29 38 dendritic dendritic ADJ dpc-5888 29 39 cells cell NOUN dpc-5888 29 40 at at ADP dpc-5888 29 41 the the DET dpc-5888 29 42 dermoepidermal dermoepidermal ADJ dpc-5888 29 43 junction junction NOUN dpc-5888 29 44 ( ( PUNCT dpc-5888 29 45 d d NOUN dpc-5888 29 46 ) ) PUNCT dpc-5888 29 47 . . PUNCT dpc-5888 30 1 hematoxylin hematoxylin PROPN dpc-5888 30 2 and and CCONJ dpc-5888 30 3 eosin eosin NOUN dpc-5888 30 4 staining stain VERB dpc-5888 30 5 from from ADP dpc-5888 30 6 the the DET dpc-5888 30 7 biopsy biopsy NOUN dpc-5888 30 8 confirmed confirm VERB dpc-5888 30 9 a a DET dpc-5888 30 10 proliferation proliferation NOUN dpc-5888 30 11 of of ADP dpc-5888 30 12 atypical atypical ADJ dpc-5888 30 13 melanocytes melanocyte NOUN dpc-5888 30 14 along along ADP dpc-5888 30 15 the the DET dpc-5888 30 16 basal basal ADJ dpc-5888 30 17 layer layer NOUN dpc-5888 30 18 , , PUNCT dpc-5888 30 19 with with ADP dpc-5888 30 20 evidence evidence NOUN dpc-5888 30 21 of of ADP dpc-5888 30 22 pagetoid pagetoid NOUN dpc-5888 30 23 spread spread VERB dpc-5888 30 24 in in ADP dpc-5888 30 25 the the DET dpc-5888 30 26 epidermis epidermis NOUN dpc-5888 30 27 ( ( PUNCT dpc-5888 30 28 e e NOUN dpc-5888 30 29 ) ) PUNCT dpc-5888 30 30 . . PUNCT dpc-5888 31 1 immunohistochemical immunohistochemical ADJ dpc-5888 31 2 staining staining NOUN dpc-5888 31 3 revealed reveal VERB dpc-5888 31 4 sox10 sox10 NOUN dpc-5888 31 5 positivity positivity NOUN dpc-5888 31 6 in in ADP dpc-5888 31 7 the the DET dpc-5888 31 8 atypical atypical ADJ dpc-5888 31 9 melanocytic melanocytic ADJ dpc-5888 31 10 proliferation proliferation NOUN dpc-5888 31 11 , , PUNCT dpc-5888 31 12 further far ADV dpc-5888 31 13 supporting support VERB dpc-5888 31 14 the the DET dpc-5888 31 15 diagnosis diagnosis NOUN dpc-5888 31 16 of of ADP dpc-5888 31 17 acral acral ADJ dpc-5888 31 18 lentiginous lentiginous ADJ dpc-5888 31 19 melanoma melanoma NOUN dpc-5888 31 20 ( ( PUNCT dpc-5888 31 21 f f NOUN dpc-5888 31 22 ) ) PUNCT dpc-5888 31 23 . . PUNCT dpc-5888 32 1 band band PROPN dpc-5888 32 2 , , PUNCT dpc-5888 32 3 with with ADP dpc-5888 32 4 irregularly irregularly ADV dpc-5888 32 5 pigmented pigment VERB dpc-5888 32 6 lines line NOUN dpc-5888 32 7 involving involve VERB dpc-5888 32 8 2/3 2/3 NUM dpc-5888 32 9 of of ADP dpc-5888 32 10 the the DET dpc-5888 32 11 nail nail NOUN dpc-5888 32 12 plate plate NOUN dpc-5888 32 13 or or CCONJ dpc-5888 32 14 the the DET dpc-5888 32 15 nailfolds nailfold NOUN dpc-5888 32 16 with with ADP dpc-5888 32 17 periungual periungual ADJ dpc-5888 32 18 pigmentation pigmentation NOUN dpc-5888 32 19 called call VERB dpc-5888 32 20 hutchinson hutchinson PROPN dpc-5888 32 21 ’s ’s PART dpc-5888 32 22 sign sign NOUN dpc-5888 32 23 [ [ X dpc-5888 32 24 2 2 NUM dpc-5888 32 25 ] ] PUNCT dpc-5888 32 26 . . PUNCT dpc-5888 33 1 however however ADV dpc-5888 33 2 , , PUNCT dpc-5888 33 3 this this DET dpc-5888 33 4 case case NOUN dpc-5888 33 5 highlights highlight VERB dpc-5888 33 6 hutchinson hutchinson PROPN dpc-5888 33 7 ’s ’s PART dpc-5888 33 8 sign sign PROPN dpc-5888 33 9 pigmentation pigmentation NOUN dpc-5888 33 10 of of ADP dpc-5888 33 11 the the DET dpc-5888 33 12 periungual periungual ADJ dpc-5888 33 13 skin skin NOUN dpc-5888 33 14 without without ADP dpc-5888 33 15 nail nail NOUN dpc-5888 33 16 plate plate NOUN dpc-5888 33 17 pigmentation pigmentation NOUN dpc-5888 33 18 as as ADP dpc-5888 33 19 an an DET dpc-5888 33 20 early early ADJ dpc-5888 33 21 indicator indicator NOUN dpc-5888 33 22 of of ADP dpc-5888 33 23 invasive invasive ADJ dpc-5888 33 24 ungual ungual ADJ dpc-5888 33 25 melanoma melanoma NOUN dpc-5888 33 26 , , PUNCT dpc-5888 33 27 but but CCONJ dpc-5888 33 28 biopsy biopsy NOUN dpc-5888 33 29 should should AUX dpc-5888 33 30 be be AUX dpc-5888 33 31 performed perform VERB dpc-5888 33 32 in in ADP dpc-5888 33 33 the the DET dpc-5888 33 34 nail nail NOUN dpc-5888 33 35 matrix matrix NOUN dpc-5888 33 36 , , PUNCT dpc-5888 33 37 origin origin NOUN dpc-5888 33 38 of of ADP dpc-5888 33 39 the the DET dpc-5888 33 40 tumor tumor NOUN dpc-5888 33 41 . . PUNCT dpc-5888 34 1 this this DET dpc-5888 34 2 uncommon uncommon ADJ dpc-5888 34 3 presentation presentation NOUN dpc-5888 34 4 could could AUX dpc-5888 34 5 lead lead VERB dpc-5888 34 6 to to ADP dpc-5888 34 7 diagnostic diagnostic ADJ dpc-5888 34 8 delays delay NOUN dpc-5888 34 9 , , PUNCT dpc-5888 34 10 further far ADV dpc-5888 34 11 worsening worsen VERB dpc-5888 34 12 the the DET dpc-5888 34 13 prognosis prognosis NOUN dpc-5888 34 14 . . PUNCT dpc-5888 35 1 clinical clinical ADJ dpc-5888 35 2 suspicion suspicion NOUN dpc-5888 35 3 is be AUX dpc-5888 35 4 critical critical ADJ dpc-5888 35 5 , , PUNCT dpc-5888 35 6 even even ADV dpc-5888 35 7 in in ADP dpc-5888 35 8 the the DET dpc-5888 35 9 absence absence NOUN dpc-5888 35 10 of of ADP dpc-5888 35 11 melanonychia melanonychia NOUN dpc-5888 35 12 , , PUNCT dpc-5888 35 13 particularly particularly ADV dpc-5888 35 14 in in ADP dpc-5888 35 15 patients patient NOUN dpc-5888 35 16 over over ADP dpc-5888 35 17 50 50 NUM dpc-5888 35 18 years year NOUN dpc-5888 35 19 of of ADP dpc-5888 35 20 age age NOUN dpc-5888 35 21 . . PUNCT dpc-5888 36 1 early early ADJ dpc-5888 36 2 biopsy biopsy NOUN dpc-5888 36 3 of of ADP dpc-5888 36 4 the the DET dpc-5888 36 5 nail nail NOUN dpc-5888 36 6 matrix matrix NOUN dpc-5888 36 7 is be AUX dpc-5888 36 8 essential essential ADJ dpc-5888 36 9 to to ADP dpc-5888 36 10 accurate accurate ADJ dpc-5888 36 11 diagnosis diagnosis NOUN dpc-5888 36 12 and and CCONJ dpc-5888 36 13 timely timely ADJ dpc-5888 36 14 treatment treatment NOUN dpc-5888 36 15 . . PUNCT dpc-5888 37 1 dermatologists dermatologist NOUN dpc-5888 37 2 should should AUX dpc-5888 37 3 maintain maintain VERB dpc-5888 37 4 a a DET dpc-5888 37 5 high high ADJ dpc-5888 37 6 index index NOUN dpc-5888 37 7 of of ADP dpc-5888 37 8 suspicion suspicion NOUN dpc-5888 37 9 for for ADP dpc-5888 37 10 any any DET dpc-5888 37 11 periungual periungual ADJ dpc-5888 37 12 pigmentation pigmentation NOUN dpc-5888 37 13 , , PUNCT dpc-5888 37 14 considering consider VERB dpc-5888 37 15 melanoma melanoma NOUN dpc-5888 37 16 in in ADP dpc-5888 37 17 the the DET dpc-5888 37 18 differential differential ADJ dpc-5888 37 19 diagnosis diagnosis NOUN dpc-5888 37 20 [ [ X dpc-5888 37 21 2 2 NUM dpc-5888 37 22 ] ] PUNCT dpc-5888 37 23 . . PUNCT dpc-5888 38 1 references reference NOUN dpc-5888 38 2 1 1 NUM dpc-5888 38 3 . . PUNCT dpc-5888 39 1 levit levit PROPN dpc-5888 39 2 ek ek PROPN dpc-5888 39 3 , , PUNCT dpc-5888 39 4 kagen kagen PROPN dpc-5888 39 5 mh mh PROPN dpc-5888 39 6 , , PUNCT dpc-5888 39 7 scher scher PROPN dpc-5888 39 8 rk rk PROPN dpc-5888 39 9 , , PUNCT dpc-5888 39 10 grossman grossman PROPN dpc-5888 39 11 m m PROPN dpc-5888 39 12 , , PUNCT dpc-5888 39 13 altman altman PROPN dpc-5888 39 14 e. e. PROPN dpc-5888 40 1 the the DET dpc-5888 40 2 abc abc PROPN dpc-5888 40 3 rule rule VERB dpc-5888 40 4 for for ADP dpc-5888 40 5 clinical clinical ADJ dpc-5888 40 6 detection detection NOUN dpc-5888 40 7 of of ADP dpc-5888 40 8 subungual subungual ADJ dpc-5888 40 9 melanoma melanoma NOUN dpc-5888 40 10 . . PUNCT dpc-5888 40 11     SPACE dpc-5888 41 1 j j PROPN dpc-5888 41 2 am be AUX dpc-5888 41 3 acad acad ADJ dpc-5888 41 4 dermatol dermatol NOUN dpc-5888 41 5 . . PUNCT dpc-5888 42 1 2000;42(2 2000;42(2 NUM dpc-5888 42 2 pt pt NOUN dpc-5888 42 3 1):269 1):269 NUM dpc-5888 42 4 - - SYM dpc-5888 42 5 274 274 NUM dpc-5888 42 6 . . PUNCT dpc-5888 42 7 doi:10.1016 doi:10.1016 PROPN dpc-5888 42 8 / / SYM dpc-5888 42 9 s0190 s0190 ADJ dpc-5888 42 10 -9622(00)90137 -9622(00)90137 ADV dpc-5888 42 11 - - PUNCT dpc-5888 42 12 3 3 NUM dpc-5888 42 13 . . PUNCT dpc-5888 42 14 pmid pmid NOUN dpc-5888 42 15 : : PUNCT dpc-5888 42 16 10642684 10642684 NUM dpc-5888 42 17 2 2 NUM dpc-5888 42 18 . . PUNCT dpc-5888 42 19 benati benati PROPN dpc-5888 42 20 e e PROPN dpc-5888 42 21 , , PUNCT dpc-5888 42 22 ribero ribero PROPN dpc-5888 42 23 s s PROPN dpc-5888 42 24 , , PUNCT dpc-5888 42 25 longo longo PROPN dpc-5888 42 26 c c NOUN dpc-5888 42 27 , , PUNCT dpc-5888 42 28 et et PROPN dpc-5888 42 29 al al PROPN dpc-5888 42 30 . . PROPN dpc-5888 42 31 clinical clinical ADJ dpc-5888 42 32 and and CCONJ dpc-5888 42 33 dermoscopic dermoscopic ADJ dpc-5888 42 34 clues clue NOUN dpc-5888 42 35 to to PART dpc-5888 42 36 differentiate differentiate VERB dpc-5888 42 37 pigmented pigmented ADJ dpc-5888 42 38 nail nail NOUN dpc-5888 42 39 bands band NOUN dpc-5888 42 40 : : PUNCT dpc-5888 42 41 an an DET dpc-5888 42 42 international international ADJ dpc-5888 42 43 dermoscopy dermoscopy NOUN dpc-5888 42 44 society society NOUN dpc-5888 42 45 study study NOUN dpc-5888 42 46 . . PUNCT dpc-5888 42 47     SPACE dpc-5888 43 1 j j PROPN dpc-5888 43 2 eur eur PROPN dpc-5888 43 3 acad acad PROPN dpc-5888 43 4 dermatol dermatol NOUN dpc-5888 43 5 venereol venereol NOUN dpc-5888 43 6 . . PUNCT dpc-5888 44 1 2017;31(4):732 2017;31(4):732 NUM dpc-5888 44 2 - - SYM dpc-5888 44 3 736 736 NUM dpc-5888 44 4 . . PUNCT dpc-5888 45 1 doi:10.1111 doi:10.1111 NOUN dpc-5888 45 2 / / SYM dpc-5888 45 3 jdv.13991 jdv.13991 PROPN dpc-5888 45 4 . . PUNCT dpc-5888 46 1 pmid pmid NOUN dpc-5888 46 2 : : PUNCT dpc-5888 46 3 27696528 27696528 NUM dpc-5888 46 4 . . PUNCT