id	sid	tid	token	lemma	pos
dpc-5921	1	1	dermatology	dermatology	NOUN
dpc-5921	1	2	:	:	PUNCT
dpc-5921	1	3	practical	practical	ADJ
dpc-5921	1	4	and	and	CCONJ
dpc-5921	1	5	conceptual	conceptual	ADJ
dpc-5921	1	6	review	review	NOUN
dpc-5921	1	7	|	|	ADV
dpc-5921	1	8	dermatol	dermatol	ADJ
dpc-5921	1	9	pract	pract	NOUN
dpc-5921	1	10	concept	concept	NOUN
dpc-5921	1	11	.	.	PUNCT
dpc-5921	2	1	2025;15(3):5921	2025;15(3):5921	NUM
dpc-5921	2	2	1	1	NUM
dpc-5921	2	3	real	real	ADJ
dpc-5921	2	4	-	-	PUNCT
dpc-5921	2	5	world	world	NOUN
dpc-5921	2	6	efficacy	efficacy	NOUN
dpc-5921	2	7	of	of	ADP
dpc-5921	2	8	tirbanibulin	tirbanibulin	PROPN
dpc-5921	2	9	in	in	ADP
dpc-5921	2	10	actinic	actinic	ADJ
dpc-5921	2	11	keratosis	keratosis	NOUN
dpc-5921	2	12	treatment	treatment	NOUN
dpc-5921	2	13	:	:	PUNCT
dpc-5921	2	14	expert	expert	ADJ
dpc-5921	2	15	consensus	consensus	NOUN
dpc-5921	2	16	and	and	CCONJ
dpc-5921	2	17	clinical	clinical	ADJ
dpc-5921	2	18	insights	insight	NOUN
dpc-5921	2	19	marco	marco	PROPN
dpc-5921	2	20	ardigò1,2	ardigò1,2	PROPN
dpc-5921	2	21	,	,	PUNCT
dpc-5921	2	22	giuseppe	giuseppe	PROPN
dpc-5921	2	23	argenziano3	argenziano3	PROPN
dpc-5921	2	24	,	,	PUNCT
dpc-5921	2	25	elena	elena	PROPN
dpc-5921	2	26	campione4	campione4	PROPN
dpc-5921	2	27	,	,	PUNCT
dpc-5921	2	28	stefania	stefania	PROPN
dpc-5921	2	29	guida5	guida5	PROPN
dpc-5921	2	30	,	,	PUNCT
dpc-5921	2	31	caterina	caterina	PROPN
dpc-5921	2	32	longo6,7	longo6,7	PROPN
dpc-5921	2	33	,	,	PUNCT
dpc-5921	2	34	giuseppe	giuseppe	PROPN
dpc-5921	2	35	micali8	micali8	PROPN
dpc-5921	2	36	,	,	PUNCT
dpc-5921	2	37	gianluca	gianluca	PROPN
dpc-5921	2	38	nazzaro9,10	nazzaro9,10	PROPN
dpc-5921	2	39	,	,	PUNCT
dpc-5921	2	40	ketty	ketty	PROPN
dpc-5921	2	41	peris11,12	peris11,12	PROPN
dpc-5921	2	42	,	,	PUNCT
dpc-5921	2	43	federico	federico	PROPN
dpc-5921	2	44	venturi13,14	venturi13,14	ADV
dpc-5921	2	45	,	,	PUNCT
dpc-5921	2	46	alessia	alessia	PROPN
dpc-5921	2	47	villani15	villani15	VERB
dpc-5921	2	48	,	,	PUNCT
dpc-5921	2	49	iris	iris	NOUN
dpc-5921	2	50	zalaudek16	zalaudek16	NOUN
dpc-5921	2	51	1	1	NUM
dpc-5921	2	52	dermatology	dermatology	NOUN
dpc-5921	2	53	unit	unit	NOUN
dpc-5921	2	54	,	,	PUNCT
dpc-5921	2	55	irccs	ircc	VERB
dpc-5921	2	56	humanitas	humanitas	NOUN
dpc-5921	2	57	research	research	NOUN
dpc-5921	2	58	hospital	hospital	NOUN
dpc-5921	2	59	,	,	PUNCT
dpc-5921	2	60	rozzano	rozzano	PROPN
dpc-5921	2	61	,	,	PUNCT
dpc-5921	2	62	italy	italy	PROPN
dpc-5921	2	63	2	2	NUM
dpc-5921	2	64	department	department	NOUN
dpc-5921	2	65	of	of	ADP
dpc-5921	2	66	biomedical	biomedical	ADJ
dpc-5921	2	67	sciences	sciences	PROPN
dpc-5921	2	68	,	,	PUNCT
dpc-5921	2	69	humanitas	humanita	NOUN
dpc-5921	2	70	university	university	NOUN
dpc-5921	2	71	,	,	PUNCT
dpc-5921	2	72	pieve	pieve	PROPN
dpc-5921	2	73	emanuele	emanuele	PROPN
dpc-5921	2	74	,	,	PUNCT
dpc-5921	2	75	milano	milano	PROPN
dpc-5921	2	76	,	,	PUNCT
dpc-5921	2	77	italy	italy	PROPN
dpc-5921	2	78	3	3	NUM
dpc-5921	2	79	dermatology	dermatology	NOUN
dpc-5921	2	80	unit	unit	NOUN
dpc-5921	2	81	,	,	PUNCT
dpc-5921	2	82	university	university	PROPN
dpc-5921	2	83	of	of	ADP
dpc-5921	2	84	campania	campania	PROPN
dpc-5921	2	85	,	,	PUNCT
dpc-5921	2	86	naples	naples	PROPN
dpc-5921	2	87	,	,	PUNCT
dpc-5921	2	88	italy	italy	PROPN
dpc-5921	2	89	4	4	NUM
dpc-5921	2	90	dermatology	dermatology	NOUN
dpc-5921	2	91	unit	unit	NOUN
dpc-5921	2	92	,	,	PUNCT
dpc-5921	2	93	department	department	NOUN
dpc-5921	2	94	of	of	ADP
dpc-5921	2	95	systems	system	NOUN
dpc-5921	2	96	medicine	medicine	NOUN
dpc-5921	2	97	,	,	PUNCT
dpc-5921	2	98	university	university	NOUN
dpc-5921	2	99	of	of	ADP
dpc-5921	2	100	rome	rome	PROPN
dpc-5921	2	101	tor	tor	PROPN
dpc-5921	2	102	vergata	vergata	PROPN
dpc-5921	2	103	,	,	PUNCT
dpc-5921	2	104	rome	rome	PROPN
dpc-5921	2	105	,	,	PUNCT
dpc-5921	2	106	italy	italy	PROPN
dpc-5921	2	107	5	5	NUM
dpc-5921	2	108	dermatology	dermatology	NOUN
dpc-5921	2	109	clinic	clinic	NOUN
dpc-5921	2	110	,	,	PUNCT
dpc-5921	2	111	irccs	ircc	VERB
dpc-5921	2	112	san	san	PROPN
dpc-5921	2	113	raffaele	raffaele	PROPN
dpc-5921	2	114	hospital	hospital	PROPN
dpc-5921	2	115	,	,	PUNCT
dpc-5921	2	116	milan	milan	PROPN
dpc-5921	2	117	,	,	PUNCT
dpc-5921	2	118	italy	italy	PROPN
dpc-5921	2	119	6	6	NUM
dpc-5921	2	120	skin	skin	NOUN
dpc-5921	2	121	cancer	cancer	NOUN
dpc-5921	2	122	center	center	NOUN
dpc-5921	2	123	,	,	PUNCT
dpc-5921	2	124	azienda	azienda	PROPN
dpc-5921	2	125	unità	unità	PROPN
dpc-5921	2	126	sanitaria	sanitaria	PROPN
dpc-5921	2	127	locale	locale	PROPN
dpc-5921	2	128	,	,	PUNCT
dpc-5921	2	129	irccs	irccs	PROPN
dpc-5921	2	130	reggio	reggio	PROPN
dpc-5921	2	131	emilia	emilia	PROPN
dpc-5921	2	132	,	,	PUNCT
dpc-5921	2	133	reggio	reggio	PROPN
dpc-5921	2	134	emilia	emilia	PROPN
dpc-5921	2	135	,	,	PUNCT
dpc-5921	2	136	italy	italy	PROPN
dpc-5921	2	137	7	7	NUM
dpc-5921	2	138	dermatology	dermatology	NOUN
dpc-5921	2	139	department	department	NOUN
dpc-5921	2	140	,	,	PUNCT
dpc-5921	2	141	university	university	NOUN
dpc-5921	2	142	of	of	ADP
dpc-5921	2	143	modena	modena	PROPN
dpc-5921	2	144	and	and	CCONJ
dpc-5921	2	145	reggio	reggio	PROPN
dpc-5921	2	146	emilia	emilia	PROPN
dpc-5921	2	147	,	,	PUNCT
dpc-5921	2	148	italy	italy	PROPN
dpc-5921	2	149	8	8	NUM
dpc-5921	2	150	dermatology	dermatology	NOUN
dpc-5921	2	151	clinic	clinic	NOUN
dpc-5921	2	152	,	,	PUNCT
dpc-5921	2	153	university	university	PROPN
dpc-5921	2	154	of	of	ADP
dpc-5921	2	155	catania	catania	PROPN
dpc-5921	2	156	,	,	PUNCT
dpc-5921	2	157	catania	catania	PROPN
dpc-5921	2	158	,	,	PUNCT
dpc-5921	2	159	italy	italy	PROPN
dpc-5921	2	160	9	9	NUM
dpc-5921	2	161	dermatology	dermatology	NOUN
dpc-5921	2	162	unit	unit	NOUN
dpc-5921	2	163	,	,	PUNCT
dpc-5921	2	164	fondazione	fondazione	PROPN
dpc-5921	2	165	irccs	irccs	NOUN
dpc-5921	2	166	ca	can	AUX
dpc-5921	2	167	’	'	PUNCT
dpc-5921	2	168	granda	granda	PROPN
dpc-5921	2	169	ospedale	ospedale	PROPN
dpc-5921	2	170	maggiore	maggiore	PROPN
dpc-5921	2	171	policlinico	policlinico	PROPN
dpc-5921	2	172	,	,	PUNCT
dpc-5921	2	173	milan	milan	PROPN
dpc-5921	2	174	,	,	PUNCT
dpc-5921	2	175	italy	italy	PROPN
dpc-5921	2	176	10	10	NUM
dpc-5921	2	177	department	department	PROPN
dpc-5921	2	178	of	of	ADP
dpc-5921	2	179	physiopathology	physiopathology	NOUN
dpc-5921	2	180	and	and	CCONJ
dpc-5921	2	181	transplantation	transplantation	NOUN
dpc-5921	2	182	,	,	PUNCT
dpc-5921	2	183	university	university	PROPN
dpc-5921	2	184	of	of	ADP
dpc-5921	2	185	milan	milan	PROPN
dpc-5921	2	186	,	,	PUNCT
dpc-5921	2	187	italy	italy	PROPN
dpc-5921	2	188	11	11	NUM
dpc-5921	2	189	dermatology	dermatology	NOUN
dpc-5921	2	190	,	,	PUNCT
dpc-5921	2	191	department	department	NOUN
dpc-5921	2	192	of	of	ADP
dpc-5921	2	193	medical	medical	ADJ
dpc-5921	2	194	science	science	NOUN
dpc-5921	2	195	and	and	CCONJ
dpc-5921	2	196	surgery	surgery	NOUN
dpc-5921	2	197	,	,	PUNCT
dpc-5921	2	198	fondazione	fondazione	PROPN
dpc-5921	2	199	policlinico	policlinico	PROPN
dpc-5921	2	200	universitario	universitario	PROPN
dpc-5921	2	201	a.	a.	PROPN
dpc-5921	2	202	gemelli	gemelli	PROPN
dpc-5921	2	203	irccs	irccs	PROPN
dpc-5921	2	204	,	,	PUNCT
dpc-5921	2	205	rome	rome	PROPN
dpc-5921	2	206	,	,	PUNCT
dpc-5921	2	207	italy	italy	PROPN
dpc-5921	2	208	12	12	NUM
dpc-5921	2	209	department	department	NOUN
dpc-5921	2	210	of	of	ADP
dpc-5921	2	211	dermatology	dermatology	NOUN
dpc-5921	2	212	,	,	PUNCT
dpc-5921	2	213	catholic	catholic	PROPN
dpc-5921	2	214	university	university	PROPN
dpc-5921	2	215	of	of	ADP
dpc-5921	2	216	the	the	DET
dpc-5921	2	217	sacred	sacred	ADJ
dpc-5921	2	218	heart	heart	NOUN
dpc-5921	2	219	,	,	PUNCT
dpc-5921	2	220	rome	rome	PROPN
dpc-5921	2	221	,	,	PUNCT
dpc-5921	2	222	italy	italy	PROPN
dpc-5921	2	223	13	13	NUM
dpc-5921	2	224	oncologic	oncologic	PROPN
dpc-5921	2	225	dermatology	dermatology	NOUN
dpc-5921	2	226	unit	unit	NOUN
dpc-5921	2	227	,	,	PUNCT
dpc-5921	2	228	irccs	irccs	PROPN
dpc-5921	2	229	azienda	azienda	PROPN
dpc-5921	2	230	ospedaliero	ospedaliero	PROPN
dpc-5921	2	231	-	-	PUNCT
dpc-5921	2	232	universitaria	universitaria	PROPN
dpc-5921	2	233	di	di	PROPN
dpc-5921	2	234	bologna	bologna	PROPN
dpc-5921	2	235	,	,	PUNCT
dpc-5921	2	236	bologna	bologna	PROPN
dpc-5921	2	237	,	,	PUNCT
dpc-5921	2	238	italy	italy	PROPN
dpc-5921	2	239	14	14	NUM
dpc-5921	2	240	department	department	PROPN
dpc-5921	2	241	of	of	ADP
dpc-5921	2	242	medical	medical	ADJ
dpc-5921	2	243	and	and	CCONJ
dpc-5921	2	244	surgical	surgical	ADJ
dpc-5921	2	245	sciences	science	NOUN
dpc-5921	2	246	,	,	PUNCT
dpc-5921	2	247	alma	alma	NOUN
dpc-5921	2	248	mater	mater	PROPN
dpc-5921	2	249	studiorum	studiorum	PROPN
dpc-5921	2	250	university	university	PROPN
dpc-5921	2	251	of	of	ADP
dpc-5921	2	252	bologna	bologna	PROPN
dpc-5921	2	253	,	,	PUNCT
dpc-5921	2	254	bologna	bologna	PROPN
dpc-5921	2	255	,	,	PUNCT
dpc-5921	2	256	italy	italy	PROPN
dpc-5921	2	257	15	15	NUM
dpc-5921	2	258	dermatology	dermatology	NOUN
dpc-5921	2	259	section	section	NOUN
dpc-5921	2	260	,	,	PUNCT
dpc-5921	2	261	department	department	NOUN
dpc-5921	2	262	of	of	ADP
dpc-5921	2	263	clinical	clinical	ADJ
dpc-5921	2	264	medicine	medicine	NOUN
dpc-5921	2	265	and	and	CCONJ
dpc-5921	2	266	surgery	surgery	NOUN
dpc-5921	2	267	,	,	PUNCT
dpc-5921	2	268	federico	federico	PROPN
dpc-5921	2	269	ii	ii	PROPN
dpc-5921	2	270	university	university	PROPN
dpc-5921	2	271	of	of	ADP
dpc-5921	2	272	naples	naples	PROPN
dpc-5921	2	273	,	,	PUNCT
dpc-5921	2	274	naples	naples	PROPN
dpc-5921	2	275	,	,	PUNCT
dpc-5921	2	276	italy	italy	PROPN
dpc-5921	2	277	16	16	NUM
dpc-5921	2	278	department	department	PROPN
dpc-5921	2	279	of	of	ADP
dpc-5921	2	280	dermatology	dermatology	NOUN
dpc-5921	2	281	and	and	CCONJ
dpc-5921	2	282	venereology	venereology	NOUN
dpc-5921	2	283	,	,	PUNCT
dpc-5921	2	284	university	university	NOUN
dpc-5921	2	285	of	of	ADP
dpc-5921	2	286	trieste	trieste	PROPN
dpc-5921	2	287	,	,	PUNCT
dpc-5921	2	288	trieste	trieste	PROPN
dpc-5921	2	289	,	,	PUNCT
dpc-5921	2	290	italy	italy	PROPN
dpc-5921	2	291	key	key	ADJ
dpc-5921	2	292	words	word	NOUN
dpc-5921	2	293	:	:	PUNCT
dpc-5921	2	294	actinic	actinic	ADJ
dpc-5921	2	295	keratosis	keratosis	NOUN
dpc-5921	2	296	,	,	PUNCT
dpc-5921	2	297	tirbanibulin	tirbanibulin	PROPN
dpc-5921	2	298	,	,	PUNCT
dpc-5921	2	299	topical	topical	ADJ
dpc-5921	2	300	treatment	treatment	NOUN
dpc-5921	2	301	,	,	PUNCT
dpc-5921	2	302	expert	expert	ADJ
dpc-5921	2	303	opinion	opinion	NOUN
dpc-5921	2	304	key	key	ADJ
dpc-5921	2	305	message	message	NOUN
dpc-5921	2	306	:	:	PUNCT
dpc-5921	2	307	tirbanibulin	tirbanibulin	PROPN
dpc-5921	2	308	use	use	NOUN
dpc-5921	2	309	in	in	ADP
dpc-5921	2	310	the	the	DET
dpc-5921	2	311	treatment	treatment	NOUN
dpc-5921	2	312	of	of	ADP
dpc-5921	2	313	actinic	actinic	ADJ
dpc-5921	2	314	keratosis	keratosis	NOUN
dpc-5921	2	315	is	be	AUX
dpc-5921	2	316	expanding	expand	VERB
dpc-5921	2	317	owing	owe	VERB
dpc-5921	2	318	to	to	ADP
dpc-5921	2	319	its	its	PRON
dpc-5921	2	320	proven	prove	VERB
dpc-5921	2	321	efficacy	efficacy	NOUN
dpc-5921	2	322	,	,	PUNCT
dpc-5921	2	323	tolerability	tolerability	NOUN
dpc-5921	2	324	,	,	PUNCT
dpc-5921	2	325	and	and	CCONJ
dpc-5921	2	326	short	short	ADJ
dpc-5921	2	327	treatment	treatment	NOUN
dpc-5921	2	328	regimen	regiman	NOUN
dpc-5921	2	329	.	.	PUNCT
dpc-5921	3	1	this	this	DET
dpc-5921	3	2	expert	expert	ADJ
dpc-5921	3	3	consensus	consensus	NOUN
dpc-5921	3	4	provides	provide	VERB
dpc-5921	3	5	guidance	guidance	NOUN
dpc-5921	3	6	on	on	ADP
dpc-5921	3	7	optimal	optimal	ADJ
dpc-5921	3	8	use	use	NOUN
dpc-5921	3	9	of	of	ADP
dpc-5921	3	10	tirbanibulin	tirbanibulin	PROPN
dpc-5921	3	11	in	in	ADP
dpc-5921	3	12	real	real	ADJ
dpc-5921	3	13	-	-	PUNCT
dpc-5921	3	14	life	life	NOUN
dpc-5921	3	15	clinical	clinical	ADJ
dpc-5921	3	16	practice	practice	NOUN
dpc-5921	3	17	.	.	PUNCT
dpc-5921	4	1	citation	citation	NOUN
dpc-5921	4	2	:	:	PUNCT
dpc-5921	4	3	ardigò	ardigò	NOUN
dpc-5921	4	4	m	m	PROPN
dpc-5921	4	5	,	,	PUNCT
dpc-5921	4	6	argenziano	argenziano	ADJ
dpc-5921	4	7	g	g	NOUN
dpc-5921	4	8	,	,	PUNCT
dpc-5921	4	9	campione	campione	PROPN
dpc-5921	4	10	e	e	NOUN
dpc-5921	4	11	,	,	PUNCT
dpc-5921	4	12	et	et	PROPN
dpc-5921	4	13	al	al	PROPN
dpc-5921	4	14	.	.	PUNCT
dpc-5921	5	1	optimal	optimal	ADJ
dpc-5921	5	2	use	use	NOUN
dpc-5921	5	3	of	of	ADP
dpc-5921	5	4	tirbanibulin	tirbanibulin	PROPN
dpc-5921	5	5	in	in	ADP
dpc-5921	5	6	the	the	DET
dpc-5921	5	7	real	real	ADJ
dpc-5921	5	8	-	-	PUNCT
dpc-5921	5	9	life	life	NOUN
dpc-5921	5	10	treatment	treatment	NOUN
dpc-5921	5	11	of	of	ADP
dpc-5921	5	12	actinic	actinic	ADJ
dpc-5921	5	13	keratosis	keratosis	NOUN
dpc-5921	5	14	:	:	PUNCT
dpc-5921	5	15	expert	expert	ADJ
dpc-5921	5	16	consensus	consensus	NOUN
dpc-5921	5	17	.	.	PUNCT
dpc-5921	6	1	dermatol	dermatol	NOUN
dpc-5921	6	2	pract	pract	PROPN
dpc-5921	6	3	concept	concept	NOUN
dpc-5921	6	4	.	.	PUNCT
dpc-5921	7	1	2025;15(3):5921	2025;15(3):5921	X
dpc-5921	7	2	.	.	PUNCT
dpc-5921	7	3	doi	doi	PROPN
dpc-5921	7	4	:	:	PUNCT
dpc-5921	7	5	https://doi.org/10.5826/dpc.1503a5921	https://doi.org/10.5826/dpc.1503a5921	PROPN
dpc-5921	7	6	accepted	accept	VERB
dpc-5921	7	7	:	:	PUNCT
dpc-5921	7	8	may	may	AUX
dpc-5921	7	9	19	19	NUM
dpc-5921	7	10	,	,	PUNCT
dpc-5921	7	11	2025	2025	NUM
dpc-5921	7	12	;	;	PUNCT
dpc-5921	7	13	published	publish	VERB
dpc-5921	7	14	:	:	PUNCT
dpc-5921	8	1	july	july	PROPN
dpc-5921	8	2	2025	2025	NUM
dpc-5921	8	3	copyright	copyright	NOUN
dpc-5921	8	4	:	:	PUNCT
dpc-5921	8	5	©	©	PROPN
dpc-5921	8	6	2025	2025	NUM
dpc-5921	8	7	ardigò	ardigò	NOUN
dpc-5921	8	8	et	et	PROPN
dpc-5921	8	9	al	al	PROPN
dpc-5921	8	10	.	.	PUNCT
dpc-5921	9	1	this	this	PRON
dpc-5921	9	2	is	be	AUX
dpc-5921	9	3	an	an	DET
dpc-5921	9	4	open	open	ADJ
dpc-5921	9	5	-	-	PUNCT
dpc-5921	9	6	access	access	NOUN
dpc-5921	9	7	article	article	NOUN
dpc-5921	9	8	distributed	distribute	VERB
dpc-5921	9	9	under	under	ADP
dpc-5921	9	10	the	the	DET
dpc-5921	9	11	terms	term	NOUN
dpc-5921	9	12	of	of	ADP
dpc-5921	9	13	the	the	DET
dpc-5921	9	14	creative	creative	ADJ
dpc-5921	9	15	commons	common	NOUN
dpc-5921	9	16	attributionnoncommercial	attributionnoncommercial	ADJ
dpc-5921	9	17	license	license	NOUN
dpc-5921	9	18	(	(	PUNCT
dpc-5921	9	19	by	by	ADP
dpc-5921	9	20	-	-	PUNCT
dpc-5921	9	21	nc-4.0	nc-4.0	NOUN
dpc-5921	9	22	)	)	PUNCT
dpc-5921	9	23	,	,	PUNCT
dpc-5921	9	24	https://creativecommons.org/licenses/by-nc/4.0/	https://creativecommons.org/licenses/by-nc/4.0/	PROPN
dpc-5921	9	25	,	,	PUNCT
dpc-5921	9	26	which	which	PRON
dpc-5921	9	27	permits	permit	VERB
dpc-5921	9	28	unrestricted	unrestricted	ADJ
dpc-5921	9	29	noncommercial	noncommercial	ADJ
dpc-5921	9	30	use	use	NOUN
dpc-5921	9	31	,	,	PUNCT
dpc-5921	9	32	distribution	distribution	NOUN
dpc-5921	9	33	,	,	PUNCT
dpc-5921	9	34	and	and	CCONJ
dpc-5921	9	35	reproduction	reproduction	NOUN
dpc-5921	9	36	in	in	ADP
dpc-5921	9	37	any	any	DET
dpc-5921	9	38	medium	medium	NOUN
dpc-5921	9	39	,	,	PUNCT
dpc-5921	9	40	provided	provide	VERB
dpc-5921	9	41	the	the	DET
dpc-5921	9	42	original	original	ADJ
dpc-5921	9	43	authors	author	NOUN
dpc-5921	9	44	and	and	CCONJ
dpc-5921	9	45	source	source	NOUN
dpc-5921	9	46	are	be	AUX
dpc-5921	9	47	credited	credit	VERB
dpc-5921	9	48	.	.	PUNCT
dpc-5921	10	1	funding	funding	NOUN
dpc-5921	10	2	:	:	PUNCT
dpc-5921	10	3	this	this	DET
dpc-5921	10	4	article	article	NOUN
dpc-5921	10	5	was	be	AUX
dpc-5921	10	6	sponsored	sponsor	VERB
dpc-5921	10	7	by	by	ADP
dpc-5921	10	8	almirall	almirall	ADJ
dpc-5921	10	9	s.p.a	s.p.a	PROPN
dpc-5921	10	10	.	.	PUNCT
dpc-5921	10	11	assistance	assistance	NOUN
dpc-5921	10	12	with	with	ADP
dpc-5921	10	13	coordination	coordination	NOUN
dpc-5921	10	14	of	of	ADP
dpc-5921	10	15	the	the	DET
dpc-5921	10	16	consensus	consensus	NOUN
dpc-5921	10	17	process	process	NOUN
dpc-5921	10	18	and	and	CCONJ
dpc-5921	10	19	medical	medical	ADJ
dpc-5921	10	20	writing	writing	NOUN
dpc-5921	10	21	was	be	AUX
dpc-5921	10	22	provided	provide	VERB
dpc-5921	10	23	by	by	ADP
dpc-5921	10	24	editamed	editamed	ADJ
dpc-5921	10	25	and	and	CCONJ
dpc-5921	10	26	funded	fund	VERB
dpc-5921	10	27	by	by	ADP
dpc-5921	10	28	almirall	almirall	ADJ
dpc-5921	10	29	s.p.a	s.p.a	PROPN
dpc-5921	10	30	.	.	PUNCT
dpc-5921	11	1	competing	compete	VERB
dpc-5921	11	2	interests	interest	NOUN
dpc-5921	11	3	:	:	PUNCT
dpc-5921	11	4	ma	ma	PROPN
dpc-5921	11	5	reports	report	VERB
dpc-5921	11	6	speaker	speaker	NOUN
dpc-5921	11	7	fees	fee	NOUN
dpc-5921	11	8	from	from	ADP
dpc-5921	11	9	almirall	almirall	ADJ
dpc-5921	11	10	,	,	PUNCT
dpc-5921	11	11	la	la	DET
dpc-5921	11	12	roche	roche	X
dpc-5921	11	13	-	-	PUNCT
dpc-5921	11	14	posay	posay	PROPN
dpc-5921	11	15	,	,	PUNCT
dpc-5921	11	16	and	and	CCONJ
dpc-5921	11	17	cantabria	cantabria	PROPN
dpc-5921	11	18	and	and	CCONJ
dpc-5921	11	19	advisory	advisory	ADJ
dpc-5921	11	20	boards	board	NOUN
dpc-5921	11	21	for	for	ADP
dpc-5921	11	22	almirall	almirall	NOUN
dpc-5921	11	23	.	.	PUNCT
dpc-5921	12	1	ec	ec	PROPN
dpc-5921	12	2	reports	report	VERB
dpc-5921	12	3	speaker	speaker	NOUN
dpc-5921	12	4	fees	fee	NOUN
dpc-5921	12	5	from	from	ADP
dpc-5921	12	6	almirall	almirall	ADJ
dpc-5921	12	7	,	,	PUNCT
dpc-5921	12	8	amgen	amgen	PROPN
dpc-5921	12	9	,	,	PUNCT
dpc-5921	12	10	bms	bms	PROPN
dpc-5921	12	11	,	,	PUNCT
dpc-5921	12	12	and	and	CCONJ
dpc-5921	12	13	ucb	ucb	NOUN
dpc-5921	12	14	and	and	CCONJ
dpc-5921	12	15	advisory	advisory	ADJ
dpc-5921	12	16	boards	board	NOUN
dpc-5921	12	17	for	for	ADP
dpc-5921	12	18	almirall	almirall	ADJ
dpc-5921	12	19	,	,	PUNCT
dpc-5921	12	20	amgen	amgen	PROPN
dpc-5921	12	21	,	,	PUNCT
dpc-5921	12	22	bms	bms	PROPN
dpc-5921	12	23	,	,	PUNCT
dpc-5921	12	24	cantabria	cantabria	PROPN
dpc-5921	12	25	,	,	PUNCT
dpc-5921	12	26	and	and	CCONJ
dpc-5921	12	27	ucb	ucb	PROPN
dpc-5921	13	1	.	.	PUNCT
dpc-5921	13	2	cl	cl	NOUN
dpc-5921	13	3	reports	report	NOUN
dpc-5921	13	4	speaker	speaker	NOUN
dpc-5921	13	5	fees	fee	NOUN
dpc-5921	13	6	from	from	ADP
dpc-5921	13	7	almirall	almirall	ADJ
dpc-5921	13	8	hermal	hermal	ADJ
dpc-5921	13	9	and	and	CCONJ
dpc-5921	13	10	advisory	advisory	ADJ
dpc-5921	13	11	boards	board	NOUN
dpc-5921	13	12	for	for	ADP
dpc-5921	13	13	regeneron	regeneron	NOUN
dpc-5921	13	14	.	.	PUNCT
dpc-5921	14	1	gn	gn	PROPN
dpc-5921	14	2	reports	report	VERB
dpc-5921	14	3	speaker	speaker	NOUN
dpc-5921	14	4	fees	fee	NOUN
dpc-5921	14	5	from	from	ADP
dpc-5921	14	6	giuliani	giuliani	PROPN
dpc-5921	14	7	,	,	PUNCT
dpc-5921	14	8	ideka	ideka	NOUN
dpc-5921	14	9	,	,	PUNCT
dpc-5921	14	10	and	and	CCONJ
dpc-5921	14	11	novartis	novartis	NOUN
dpc-5921	14	12	and	and	CCONJ
dpc-5921	14	13	advisory	advisory	ADJ
dpc-5921	14	14	boards	board	NOUN
dpc-5921	14	15	for	for	ADP
dpc-5921	14	16	almirall	almirall	ADJ
dpc-5921	14	17	,	,	PUNCT
dpc-5921	14	18	l’oreal	l’oreal	ADJ
dpc-5921	14	19	,	,	PUNCT
dpc-5921	14	20	and	and	CCONJ
dpc-5921	14	21	novartis	novartis	PROPN
dpc-5921	14	22	.	.	PUNCT
dpc-5921	15	1	kp	kp	PROPN
dpc-5921	15	2	reports	report	VERB
dpc-5921	15	3	grants	grant	NOUN
dpc-5921	15	4	from	from	ADP
dpc-5921	15	5	abbvie	abbvie	PROPN
dpc-5921	15	6	,	,	PUNCT
dpc-5921	15	7	almirall	almirall	ADJ
dpc-5921	15	8	,	,	PUNCT
dpc-5921	15	9	lilly	lilly	PROPN
dpc-5921	15	10	,	,	PUNCT
dpc-5921	15	11	novartis	novartis	NOUN
dpc-5921	15	12	,	,	PUNCT
dpc-5921	15	13	and	and	CCONJ
dpc-5921	15	14	sanofi	sanofi	NOUN
dpc-5921	15	15	,	,	PUNCT
dpc-5921	15	16	consulting	consult	VERB
dpc-5921	15	17	fees	fee	NOUN
dpc-5921	15	18	from	from	ADP
dpc-5921	15	19	galderma	galderma	PROPN
dpc-5921	15	20	,	,	PUNCT
dpc-5921	15	21	leo	leo	PROPN
dpc-5921	15	22	pharma	pharma	PROPN
dpc-5921	15	23	,	,	PUNCT
dpc-5921	15	24	lilly	lilly	PROPN
dpc-5921	15	25	,	,	PUNCT
dpc-5921	15	26	and	and	CCONJ
dpc-5921	15	27	sanofi	sanofi	NOUN
dpc-5921	15	28	,	,	PUNCT
dpc-5921	15	29	and	and	CCONJ
dpc-5921	15	30	participation	participation	NOUN
dpc-5921	15	31	in	in	ADP
dpc-5921	15	32	advisory	advisory	ADJ
dpc-5921	15	33	boards	board	NOUN
dpc-5921	15	34	for	for	ADP
dpc-5921	15	35	abbvie	abbvie	PROPN
dpc-5921	15	36	,	,	PUNCT
dpc-5921	15	37	almirall	almirall	ADJ
dpc-5921	15	38	,	,	PUNCT
dpc-5921	15	39	biogen	biogen	PROPN
dpc-5921	15	40	,	,	PUNCT
dpc-5921	15	41	galderma	galderma	PROPN
dpc-5921	15	42	,	,	PUNCT
dpc-5921	15	43	leo	leo	PROPN
dpc-5921	15	44	pharma	pharma	PROPN
dpc-5921	15	45	,	,	PUNCT
dpc-5921	15	46	lilly	lilly	PROPN
dpc-5921	15	47	,	,	PUNCT
dpc-5921	15	48	msd	msd	PROPN
dpc-5921	15	49	,	,	PUNCT
dpc-5921	15	50	pierre	pierre	PROPN
dpc-5921	15	51	fabre	fabre	PROPN
dpc-5921	15	52	,	,	PUNCT
dpc-5921	15	53	regeneron	regeneron	PROPN
dpc-5921	15	54	,	,	PUNCT
dpc-5921	15	55	sun	sun	PROPN
dpc-5921	15	56	pharma	pharma	PROPN
dpc-5921	15	57	,	,	PUNCT
dpc-5921	15	58	janssen	janssen	PROPN
dpc-5921	15	59	,	,	PUNCT
dpc-5921	15	60	and	and	CCONJ
dpc-5921	15	61	sanofi	sanofi	PROPN
dpc-5921	15	62	.	.	PUNCT
dpc-5921	16	1	av	av	PROPN
dpc-5921	16	2	reports	report	VERB
dpc-5921	16	3	speaker	speaker	NOUN
dpc-5921	16	4	fees	fee	NOUN
dpc-5921	16	5	from	from	ADP
dpc-5921	16	6	almirall	almirall	ADJ
dpc-5921	16	7	.	.	PUNCT
dpc-5921	17	1	iz	iz	ADP
dpc-5921	17	2	reports	report	VERB
dpc-5921	17	3	speaker	speaker	NOUN
dpc-5921	17	4	fees	fee	NOUN
dpc-5921	17	5	from	from	ADP
dpc-5921	17	6	almirall	almirall	ADJ
dpc-5921	17	7	hermal	hermal	PROPN
dpc-5921	17	8	,	,	PUNCT
dpc-5921	17	9	sanofi	sanofi	PROPN
dpc-5921	17	10	,	,	PUNCT
dpc-5921	17	11	la	la	X
dpc-5921	17	12	roche	roche	X
dpc-5921	17	13	-	-	PUNCT
dpc-5921	17	14	posay	posay	PROPN
dpc-5921	17	15	,	,	PUNCT
dpc-5921	17	16	bioderma	bioderma	NOUN
dpc-5921	17	17	,	,	PUNCT
dpc-5921	17	18	canova	canova	PROPN
dpc-5921	17	19	,	,	PUNCT
dpc-5921	17	20	msd	msd	PROPN
dpc-5921	17	21	,	,	PUNCT
dpc-5921	17	22	sanofi	sanofi	PROPN
dpc-5921	17	23	genzyme	genzyme	PROPN
dpc-5921	17	24	,	,	PUNCT
dpc-5921	17	25	and	and	CCONJ
dpc-5921	17	26	fotofinder	fotofinder	NOUN
dpc-5921	17	27	and	and	CCONJ
dpc-5921	17	28	advisory	advisory	ADJ
dpc-5921	17	29	boards	board	NOUN
dpc-5921	17	30	for	for	ADP
dpc-5921	17	31	philogen	philogen	NOUN
dpc-5921	17	32	and	and	CCONJ
dpc-5921	17	33	regeneron	regeneron	PROPN
dpc-5921	17	34	.	.	PUNCT
dpc-5921	18	1	sg	sg	PROPN
dpc-5921	18	2	reports	report	VERB
dpc-5921	18	3	speaker	speaker	NOUN
dpc-5921	18	4	fees	fee	NOUN
dpc-5921	18	5	from	from	ADP
dpc-5921	18	6	l’oreal	l’oreal	ADJ
dpc-5921	18	7	and	and	CCONJ
dpc-5921	18	8	almirall	almirall	ADJ
dpc-5921	18	9	and	and	CCONJ
dpc-5921	18	10	consultation	consultation	NOUN
dpc-5921	18	11	fees	fee	NOUN
dpc-5921	18	12	from	from	ADP
dpc-5921	18	13	istituto	istituto	PROPN
dpc-5921	18	14	ganassini	ganassini	PROPN
dpc-5921	18	15	,	,	PUNCT
dpc-5921	18	16	merz	merz	PROPN
dpc-5921	18	17	aesthetics	aesthetics	PROPN
dpc-5921	18	18	.	.	PUNCT
dpc-5921	19	1	ga	ga	PROPN
dpc-5921	19	2	,	,	PUNCT
dpc-5921	19	3	gm	gm	PROPN
dpc-5921	19	4	,	,	PUNCT
dpc-5921	19	5	and	and	CCONJ
dpc-5921	19	6	fv	fv	PROPN
dpc-5921	19	7	report	report	VERB
dpc-5921	19	8	no	no	DET
dpc-5921	19	9	conflicts	conflict	NOUN
dpc-5921	19	10	of	of	ADP
dpc-5921	19	11	interest	interest	NOUN
dpc-5921	19	12	.	.	PUNCT
dpc-5921	20	1	authorship	authorship	NOUN
dpc-5921	20	2	:	:	PUNCT
dpc-5921	20	3	all	all	DET
dpc-5921	20	4	authors	author	NOUN
dpc-5921	20	5	have	have	AUX
dpc-5921	20	6	contributed	contribute	VERB
dpc-5921	20	7	significantly	significantly	ADV
dpc-5921	20	8	to	to	ADP
dpc-5921	20	9	this	this	DET
dpc-5921	20	10	publication	publication	NOUN
dpc-5921	20	11	.	.	PUNCT
dpc-5921	21	1	corresponding	correspond	VERB
dpc-5921	21	2	author	author	NOUN
dpc-5921	21	3	:	:	PUNCT
dpc-5921	21	4	marco	marco	PROPN
dpc-5921	21	5	ardigò	ardigò	PROPN
dpc-5921	21	6	,	,	PUNCT
dpc-5921	21	7	md	md	PROPN
dpc-5921	21	8	,	,	PUNCT
dpc-5921	21	9	department	department	PROPN
dpc-5921	21	10	of	of	ADP
dpc-5921	21	11	biomedical	biomedical	ADJ
dpc-5921	21	12	sciences	sciences	PROPN
dpc-5921	21	13	,	,	PUNCT
dpc-5921	21	14	humanitas	humanita	NOUN
dpc-5921	21	15	university	university	NOUN
dpc-5921	21	16	,	,	PUNCT
dpc-5921	21	17	pieve	pieve	PROPN
dpc-5921	21	18	emanuele	emanuele	PROPN
dpc-5921	21	19	(	(	PUNCT
dpc-5921	21	20	mi	mi	PROPN
dpc-5921	21	21	)	)	PUNCT
dpc-5921	21	22	,	,	PUNCT
dpc-5921	21	23	italy	italy	PROPN
dpc-5921	21	24	.	.	PUNCT
dpc-5921	22	1	e	e	X
dpc-5921	22	2	-	-	NOUN
dpc-5921	22	3	mail	mail	NOUN
dpc-5921	22	4	:	:	PUNCT
dpc-5921	22	5	marco.ardigo@hunimed.eu	marco.ardigo@hunimed.eu	PROPN
dpc-5921	22	6	2	2	NUM
dpc-5921	22	7	review	review	NOUN
dpc-5921	22	8	|	|	ADV
dpc-5921	22	9	dermatol	dermatol	ADJ
dpc-5921	22	10	pract	pract	NOUN
dpc-5921	22	11	concept	concept	NOUN
dpc-5921	22	12	.	.	PUNCT
dpc-5921	23	1	2025;15(3):5921	2025;15(3):5921	NUM
dpc-5921	23	2	introduction	introduction	NOUN
dpc-5921	23	3	actinic	actinic	ADJ
dpc-5921	23	4	keratosis	keratosis	NOUN
dpc-5921	23	5	(	(	PUNCT
dpc-5921	23	6	ak	ak	PROPN
dpc-5921	23	7	)	)	PUNCT
dpc-5921	23	8	is	be	AUX
dpc-5921	23	9	a	a	DET
dpc-5921	23	10	chronic	chronic	ADJ
dpc-5921	23	11	skin	skin	NOUN
dpc-5921	23	12	disease	disease	NOUN
dpc-5921	23	13	characterized	characterize	VERB
dpc-5921	23	14	by	by	ADP
dpc-5921	23	15	the	the	DET
dpc-5921	23	16	abnormal	abnormal	ADJ
dpc-5921	23	17	proliferation	proliferation	NOUN
dpc-5921	23	18	of	of	ADP
dpc-5921	23	19	epidermal	epidermal	ADJ
dpc-5921	23	20	keratinocytes	keratinocyte	NOUN
dpc-5921	23	21	that	that	PRON
dpc-5921	23	22	typically	typically	ADV
dpc-5921	23	23	presents	present	VERB
dpc-5921	23	24	as	as	ADP
dpc-5921	23	25	scaly	scaly	NOUN
dpc-5921	23	26	erythematous	erythematous	ADJ
dpc-5921	23	27	papules	papule	NOUN
dpc-5921	23	28	or	or	CCONJ
dpc-5921	23	29	hyperkeratotic	hyperkeratotic	ADJ
dpc-5921	23	30	plaques	plaque	NOUN
dpc-5921	23	31	in	in	ADP
dpc-5921	23	32	chronically	chronically	ADV
dpc-5921	23	33	sun	sun	NOUN
dpc-5921	23	34	-	-	PUNCT
dpc-5921	23	35	exposed	expose	VERB
dpc-5921	23	36	areas	area	NOUN
dpc-5921	23	37	[	[	X
dpc-5921	23	38	1,2	1,2	NUM
dpc-5921	23	39	]	]	PUNCT
dpc-5921	23	40	.	.	PUNCT
dpc-5921	24	1	ak	ak	PROPN
dpc-5921	24	2	lesions	lesion	NOUN
dpc-5921	24	3	are	be	AUX
dpc-5921	24	4	considered	consider	VERB
dpc-5921	24	5	either	either	CCONJ
dpc-5921	24	6	a	a	DET
dpc-5921	24	7	precursor	precursor	NOUN
dpc-5921	24	8	or	or	CCONJ
dpc-5921	24	9	an	an	DET
dpc-5921	24	10	initial	initial	ADJ
dpc-5921	24	11	and	and	CCONJ
dpc-5921	24	12	superficial	superficial	ADJ
dpc-5921	24	13	form	form	NOUN
dpc-5921	24	14	of	of	ADP
dpc-5921	24	15	cutaneous	cutaneous	ADJ
dpc-5921	24	16	squamous	squamous	ADJ
dpc-5921	24	17	cell	cell	NOUN
dpc-5921	24	18	carcinoma	carcinoma	NOUN
dpc-5921	24	19	(	(	PUNCT
dpc-5921	24	20	cscc	cscc	ADJ
dpc-5921	24	21	)	)	PUNCT
dpc-5921	24	22	,	,	PUNCT
dpc-5921	24	23	although	although	SCONJ
dpc-5921	24	24	low	low	ADJ
dpc-5921	24	25	rates	rate	NOUN
dpc-5921	24	26	of	of	ADP
dpc-5921	24	27	progression	progression	NOUN
dpc-5921	24	28	to	to	PART
dpc-5921	24	29	invasive	invasive	ADJ
dpc-5921	24	30	cscc	cscc	NOUN
dpc-5921	24	31	have	have	AUX
dpc-5921	24	32	been	be	AUX
dpc-5921	24	33	reported	report	VERB
dpc-5921	24	34	,	,	PUNCT
dpc-5921	24	35	ranging	range	VERB
dpc-5921	24	36	from	from	ADP
dpc-5921	24	37	0	0	NUM
dpc-5921	24	38	%	%	NOUN
dpc-5921	24	39	to	to	PART
dpc-5921	24	40	0.075	0.075	NUM
dpc-5921	24	41	%	%	NOUN
dpc-5921	24	42	per	per	ADP
dpc-5921	24	43	lesion	lesion	NOUN
dpc-5921	24	44	-	-	PUNCT
dpc-5921	24	45	year	year	NOUN
dpc-5921	24	46	[	[	X
dpc-5921	24	47	1,3	1,3	NUM
dpc-5921	24	48	]	]	PUNCT
dpc-5921	24	49	.	.	PUNCT
dpc-5921	25	1	mutations	mutation	NOUN
dpc-5921	25	2	in	in	ADP
dpc-5921	25	3	oncogenic	oncogenic	ADJ
dpc-5921	25	4	and	and	CCONJ
dpc-5921	25	5	tumor	tumor	NOUN
dpc-5921	25	6	suppressing	suppress	VERB
dpc-5921	25	7	genes	gene	NOUN
dpc-5921	25	8	(	(	PUNCT
dpc-5921	25	9	e.g.	e.g.	ADV
dpc-5921	25	10	,	,	PUNCT
dpc-5921	25	11	p53	p53	NOUN
dpc-5921	25	12	,	,	PUNCT
dpc-5921	25	13	cdkn2a	cdkn2a	PROPN
dpc-5921	25	14	and	and	CCONJ
dpc-5921	25	15	pten	pten	VERB
dpc-5921	25	16	)	)	PUNCT
dpc-5921	25	17	induced	induce	VERB
dpc-5921	25	18	by	by	ADP
dpc-5921	25	19	cumulative	cumulative	ADJ
dpc-5921	25	20	ultraviolet	ultraviolet	PROPN
dpc-5921	25	21	b	b	PROPN
dpc-5921	25	22	(	(	PUNCT
dpc-5921	25	23	uvb	uvb	ADJ
dpc-5921	25	24	)	)	PUNCT
dpc-5921	25	25	radiation	radiation	NOUN
dpc-5921	25	26	are	be	AUX
dpc-5921	25	27	believed	believe	VERB
dpc-5921	25	28	to	to	PART
dpc-5921	25	29	be	be	AUX
dpc-5921	25	30	the	the	DET
dpc-5921	25	31	main	main	ADJ
dpc-5921	25	32	factor	factor	NOUN
dpc-5921	25	33	in	in	ADP
dpc-5921	25	34	the	the	DET
dpc-5921	25	35	pathogenesis	pathogenesis	NOUN
dpc-5921	25	36	of	of	ADP
dpc-5921	25	37	both	both	CCONJ
dpc-5921	25	38	ak	ak	PROPN
dpc-5921	25	39	and	and	CCONJ
dpc-5921	25	40	cscc	cscc	VERB
dpc-5921	26	1	[	[	X
dpc-5921	26	2	1	1	NUM
dpc-5921	26	3	]	]	PUNCT
dpc-5921	26	4	.	.	PUNCT
dpc-5921	27	1	important	important	ADJ
dpc-5921	27	2	risk	risk	NOUN
dpc-5921	27	3	factors	factor	NOUN
dpc-5921	27	4	for	for	ADP
dpc-5921	27	5	the	the	DET
dpc-5921	27	6	development	development	NOUN
dpc-5921	27	7	of	of	ADP
dpc-5921	27	8	ak	ak	PROPN
dpc-5921	27	9	include	include	VERB
dpc-5921	27	10	male	male	ADJ
dpc-5921	27	11	sex	sex	NOUN
dpc-5921	27	12	,	,	PUNCT
dpc-5921	27	13	age	age	NOUN
dpc-5921	27	14	>	>	NOUN
dpc-5921	27	15	45	45	NUM
dpc-5921	27	16	years	year	NOUN
dpc-5921	27	17	,	,	PUNCT
dpc-5921	27	18	light	light	PROPN
dpc-5921	27	19	fitzpatrick	fitzpatrick	PROPN
dpc-5921	27	20	phototypes	phototype	NOUN
dpc-5921	27	21	,	,	PUNCT
dpc-5921	27	22	and	and	CCONJ
dpc-5921	27	23	the	the	DET
dpc-5921	27	24	use	use	NOUN
dpc-5921	27	25	of	of	ADP
dpc-5921	27	26	photosensitizing	photosensitize	VERB
dpc-5921	27	27	drugs	drug	NOUN
dpc-5921	27	28	[	[	X
dpc-5921	27	29	1,4	1,4	NUM
dpc-5921	27	30	]	]	PUNCT
dpc-5921	27	31	.	.	PUNCT
dpc-5921	28	1	the	the	DET
dpc-5921	28	2	concept	concept	NOUN
dpc-5921	28	3	of	of	ADP
dpc-5921	28	4	field	field	NOUN
dpc-5921	28	5	cancerization	cancerization	NOUN
dpc-5921	28	6	(	(	PUNCT
dpc-5921	28	7	fc	fc	PROPN
dpc-5921	28	8	)	)	PUNCT
dpc-5921	28	9	,	,	PUNCT
dpc-5921	28	10	generally	generally	ADV
dpc-5921	28	11	referred	refer	VERB
dpc-5921	28	12	to	to	ADP
dpc-5921	28	13	as	as	ADP
dpc-5921	28	14	an	an	DET
dpc-5921	28	15	area	area	NOUN
dpc-5921	28	16	of	of	ADP
dpc-5921	28	17	subclinical	subclinical	ADJ
dpc-5921	28	18	changes	change	NOUN
dpc-5921	28	19	surrounding	surround	VERB
dpc-5921	28	20	ak	ak	PROPN
dpc-5921	28	21	lesions	lesion	NOUN
dpc-5921	28	22	that	that	PRON
dpc-5921	28	23	displays	display	VERB
dpc-5921	28	24	genetic	genetic	ADJ
dpc-5921	28	25	changes	change	NOUN
dpc-5921	28	26	similar	similar	ADJ
dpc-5921	28	27	to	to	ADP
dpc-5921	28	28	those	those	PRON
dpc-5921	28	29	found	find	VERB
dpc-5921	28	30	in	in	ADP
dpc-5921	28	31	ak	ak	PROPN
dpc-5921	28	32	,	,	PUNCT
dpc-5921	28	33	has	have	VERB
dpc-5921	28	34	diagnostic	diagnostic	ADJ
dpc-5921	28	35	and	and	CCONJ
dpc-5921	28	36	prognostic	prognostic	ADJ
dpc-5921	28	37	implications	implication	NOUN
dpc-5921	28	38	and	and	CCONJ
dpc-5921	28	39	is	be	AUX
dpc-5921	28	40	an	an	DET
dpc-5921	28	41	important	important	ADJ
dpc-5921	28	42	aspect	aspect	NOUN
dpc-5921	28	43	in	in	ADP
dpc-5921	28	44	the	the	DET
dpc-5921	28	45	management	management	NOUN
dpc-5921	28	46	of	of	ADP
dpc-5921	28	47	ak	ak	PROPN
dpc-5921	29	1	[	[	X
dpc-5921	29	2	1,3,5	1,3,5	NUM
dpc-5921	29	3	]	]	X
dpc-5921	29	4	.	.	PUNCT
dpc-5921	30	1	a	a	DET
dpc-5921	30	2	vast	vast	ADJ
dpc-5921	30	3	array	array	NOUN
dpc-5921	30	4	of	of	ADP
dpc-5921	30	5	treatments	treatment	NOUN
dpc-5921	30	6	for	for	ADP
dpc-5921	30	7	ak	ak	PROPN
dpc-5921	30	8	,	,	PUNCT
dpc-5921	30	9	either	either	CCONJ
dpc-5921	30	10	lesionor	lesionor	NOUN
dpc-5921	30	11	field	field	NOUN
dpc-5921	30	12	-	-	PUNCT
dpc-5921	30	13	directed	direct	VERB
dpc-5921	30	14	,	,	PUNCT
dpc-5921	30	15	is	be	AUX
dpc-5921	30	16	currently	currently	ADV
dpc-5921	30	17	available	available	ADJ
dpc-5921	30	18	,	,	PUNCT
dpc-5921	30	19	including	include	VERB
dpc-5921	30	20	topical	topical	ADJ
dpc-5921	30	21	drugs	drug	NOUN
dpc-5921	30	22	,	,	PUNCT
dpc-5921	30	23	surgical	surgical	ADJ
dpc-5921	30	24	procedures	procedure	NOUN
dpc-5921	30	25	,	,	PUNCT
dpc-5921	30	26	cryotherapy	cryotherapy	NOUN
dpc-5921	30	27	,	,	PUNCT
dpc-5921	30	28	laser	laser	NOUN
dpc-5921	30	29	ablation	ablation	NOUN
dpc-5921	30	30	,	,	PUNCT
dpc-5921	30	31	and	and	CCONJ
dpc-5921	30	32	photodynamic	photodynamic	ADJ
dpc-5921	30	33	therapy	therapy	NOUN
dpc-5921	30	34	.	.	PUNCT
dpc-5921	31	1	however	however	ADV
dpc-5921	31	2	,	,	PUNCT
dpc-5921	31	3	many	many	ADJ
dpc-5921	31	4	therapies	therapy	NOUN
dpc-5921	31	5	are	be	AUX
dpc-5921	31	6	associated	associate	VERB
dpc-5921	31	7	with	with	ADP
dpc-5921	31	8	important	important	ADJ
dpc-5921	31	9	local	local	ADJ
dpc-5921	31	10	or	or	CCONJ
dpc-5921	31	11	systemic	systemic	ADJ
dpc-5921	31	12	adverse	adverse	ADJ
dpc-5921	31	13	reactions	reaction	NOUN
dpc-5921	31	14	,	,	PUNCT
dpc-5921	31	15	and	and	CCONJ
dpc-5921	31	16	they	they	PRON
dpc-5921	31	17	often	often	ADV
dpc-5921	31	18	require	require	VERB
dpc-5921	31	19	a	a	DET
dpc-5921	31	20	long	long	ADJ
dpc-5921	31	21	duration	duration	NOUN
dpc-5921	31	22	of	of	ADP
dpc-5921	31	23	treatment	treatment	NOUN
dpc-5921	31	24	,	,	PUNCT
dpc-5921	31	25	resulting	result	VERB
dpc-5921	31	26	in	in	ADP
dpc-5921	31	27	poor	poor	ADJ
dpc-5921	31	28	patient	patient	ADJ
dpc-5921	31	29	adherence	adherence	NOUN
dpc-5921	31	30	and	and	CCONJ
dpc-5921	31	31	suboptimal	suboptimal	ADJ
dpc-5921	31	32	outcomes	outcome	NOUN
dpc-5921	32	1	[	[	X
dpc-5921	32	2	1,4	1,4	NUM
dpc-5921	32	3	]	]	PUNCT
dpc-5921	32	4	.	.	PUNCT
dpc-5921	33	1	the	the	DET
dpc-5921	33	2	recently	recently	ADV
dpc-5921	33	3	introduced	introduce	VERB
dpc-5921	33	4	tirbanibulin	tirbanibulin	PROPN
dpc-5921	33	5	ointment	ointment	NOUN
dpc-5921	33	6	,	,	PUNCT
dpc-5921	33	7	a	a	DET
dpc-5921	33	8	promising	promising	ADJ
dpc-5921	33	9	topical	topical	ADJ
dpc-5921	33	10	treatment	treatment	NOUN
dpc-5921	33	11	option	option	NOUN
dpc-5921	33	12	that	that	PRON
dpc-5921	33	13	targets	target	VERB
dpc-5921	33	14	both	both	DET
dpc-5921	33	15	ak	ak	PROPN
dpc-5921	33	16	lesions	lesion	NOUN
dpc-5921	33	17	and	and	CCONJ
dpc-5921	33	18	surrounding	surround	VERB
dpc-5921	33	19	fc	fc	PROPN
dpc-5921	33	20	,	,	PUNCT
dpc-5921	33	21	has	have	AUX
dpc-5921	33	22	rapidly	rapidly	ADV
dpc-5921	33	23	gained	gain	VERB
dpc-5921	33	24	favor	favor	NOUN
dpc-5921	33	25	among	among	ADP
dpc-5921	33	26	dermatologists	dermatologist	NOUN
dpc-5921	33	27	mainly	mainly	ADV
dpc-5921	33	28	due	due	ADP
dpc-5921	33	29	to	to	ADP
dpc-5921	33	30	its	its	PRON
dpc-5921	33	31	good	good	ADJ
dpc-5921	33	32	tolerability	tolerability	NOUN
dpc-5921	33	33	and	and	CCONJ
dpc-5921	33	34	ease	ease	NOUN
dpc-5921	33	35	of	of	ADP
dpc-5921	33	36	use	use	NOUN
dpc-5921	33	37	,	,	PUNCT
dpc-5921	33	38	with	with	ADP
dpc-5921	33	39	a	a	DET
dpc-5921	33	40	short	short	ADJ
dpc-5921	33	41	-	-	PUNCT
dpc-5921	33	42	term	term	NOUN
dpc-5921	33	43	course	course	NOUN
dpc-5921	33	44	of	of	ADP
dpc-5921	33	45	therapy	therapy	NOUN
dpc-5921	33	46	(	(	PUNCT
dpc-5921	33	47	once	once	ADV
dpc-5921	33	48	daily	daily	ADJ
dpc-5921	33	49	application	application	NOUN
dpc-5921	33	50	for	for	ADP
dpc-5921	33	51	five	five	NUM
dpc-5921	33	52	days	day	NOUN
dpc-5921	33	53	)	)	PUNCT
dpc-5921	34	1	[	[	X
dpc-5921	34	2	1,3,6,7	1,3,6,7	NUM
dpc-5921	34	3	]	]	X
dpc-5921	34	4	.	.	PUNCT
dpc-5921	35	1	a	a	DET
dpc-5921	35	2	first	first	ADJ
dpc-5921	35	3	-	-	PUNCT
dpc-5921	35	4	in	in	ADP
dpc-5921	35	5	-	-	PUNCT
dpc-5921	35	6	class	class	NOUN
dpc-5921	35	7	microtubule	microtubule	NOUN
dpc-5921	35	8	inhibitor	inhibitor	NOUN
dpc-5921	35	9	,	,	PUNCT
dpc-5921	35	10	tirbanibulin	tirbanibulin	PROPN
dpc-5921	35	11	targets	target	VERB
dpc-5921	35	12	tubulin	tubulin	NOUN
dpc-5921	35	13	polymerization	polymerization	NOUN
dpc-5921	35	14	and	and	CCONJ
dpc-5921	35	15	src	src	NOUN
dpc-5921	35	16	tyrosine	tyrosine	PROPN
dpc-5921	35	17	kinase	kinase	PROPN
dpc-5921	35	18	signaling	signal	VERB
dpc-5921	35	19	,	,	PUNCT
dpc-5921	35	20	two	two	NUM
dpc-5921	35	21	pathways	pathway	NOUN
dpc-5921	35	22	that	that	PRON
dpc-5921	35	23	are	be	AUX
dpc-5921	35	24	upregulated	upregulate	VERB
dpc-5921	35	25	in	in	ADP
dpc-5921	35	26	ak	ak	PROPN
dpc-5921	35	27	and	and	CCONJ
dpc-5921	35	28	cscc	cscc	VERB
dpc-5921	36	1	[	[	X
dpc-5921	36	2	6,7	6,7	NUM
dpc-5921	36	3	]	]	PUNCT
dpc-5921	36	4	.	.	PUNCT
dpc-5921	37	1	tirbanibulin	tirbanibulin	PROPN
dpc-5921	37	2	has	have	AUX
dpc-5921	37	3	demonstrated	demonstrate	VERB
dpc-5921	37	4	efficacy	efficacy	NOUN
dpc-5921	37	5	in	in	ADP
dpc-5921	37	6	clearing	clear	VERB
dpc-5921	37	7	ak	ak	PROPN
dpc-5921	37	8	lesions	lesion	NOUN
dpc-5921	37	9	,	,	PUNCT
dpc-5921	37	10	with	with	ADP
dpc-5921	37	11	a	a	DET
dpc-5921	37	12	good	good	ADJ
dpc-5921	37	13	tolerability	tolerability	NOUN
dpc-5921	37	14	profile	profile	NOUN
dpc-5921	37	15	,	,	PUNCT
dpc-5921	37	16	in	in	ADP
dpc-5921	37	17	large	large	ADJ
dpc-5921	37	18	randomized	randomized	ADJ
dpc-5921	37	19	clinical	clinical	ADJ
dpc-5921	37	20	trials	trial	NOUN
dpc-5921	37	21	as	as	ADV
dpc-5921	37	22	well	well	ADV
dpc-5921	37	23	as	as	ADP
dpc-5921	37	24	in	in	ADP
dpc-5921	37	25	real	real	ADJ
dpc-5921	37	26	-	-	PUNCT
dpc-5921	37	27	world	world	NOUN
dpc-5921	37	28	studies	study	NOUN
dpc-5921	37	29	and	and	CCONJ
dpc-5921	37	30	is	be	AUX
dpc-5921	37	31	listed	list	VERB
dpc-5921	37	32	among	among	ADP
dpc-5921	37	33	recommended	recommend	VERB
dpc-5921	37	34	options	option	NOUN
dpc-5921	37	35	for	for	ADP
dpc-5921	37	36	the	the	DET
dpc-5921	37	37	treatment	treatment	NOUN
dpc-5921	37	38	of	of	ADP
dpc-5921	37	39	ak	ak	PROPN
dpc-5921	37	40	in	in	ADP
dpc-5921	37	41	all	all	DET
dpc-5921	37	42	major	major	ADJ
dpc-5921	37	43	international	international	ADJ
dpc-5921	37	44	guidelines	guideline	NOUN
dpc-5921	37	45	[	[	X
dpc-5921	37	46	1,7	1,7	NUM
dpc-5921	37	47	-	-	SYM
dpc-5921	37	48	11	11	NUM
dpc-5921	37	49	]	]	PUNCT
dpc-5921	37	50	.	.	PUNCT
dpc-5921	38	1	given	give	VERB
dpc-5921	38	2	the	the	DET
dpc-5921	38	3	chronic	chronic	NOUN
dpc-5921	38	4	,	,	PUNCT
dpc-5921	38	5	relapsing	relapse	VERB
dpc-5921	38	6	nature	nature	NOUN
dpc-5921	38	7	of	of	ADP
dpc-5921	38	8	ak	ak	PROPN
dpc-5921	38	9	,	,	PUNCT
dpc-5921	38	10	the	the	DET
dpc-5921	38	11	growing	grow	VERB
dpc-5921	38	12	body	body	NOUN
dpc-5921	38	13	of	of	ADP
dpc-5921	38	14	knowledge	knowledge	NOUN
dpc-5921	38	15	about	about	ADP
dpc-5921	38	16	its	its	PRON
dpc-5921	38	17	pathophysiology	pathophysiology	NOUN
dpc-5921	38	18	,	,	PUNCT
dpc-5921	38	19	and	and	CCONJ
dpc-5921	38	20	the	the	DET
dpc-5921	38	21	increasing	increase	VERB
dpc-5921	38	22	availability	availability	NOUN
dpc-5921	38	23	of	of	ADP
dpc-5921	38	24	treatment	treatment	NOUN
dpc-5921	38	25	options	option	NOUN
dpc-5921	38	26	,	,	PUNCT
dpc-5921	38	27	clinicians	clinician	NOUN
dpc-5921	38	28	face	face	VERB
dpc-5921	38	29	many	many	ADJ
dpc-5921	38	30	challenges	challenge	NOUN
dpc-5921	38	31	in	in	ADP
dpc-5921	38	32	the	the	DET
dpc-5921	38	33	long	long	ADJ
dpc-5921	38	34	-	-	PUNCT
dpc-5921	38	35	term	term	NOUN
dpc-5921	38	36	management	management	NOUN
dpc-5921	38	37	of	of	ADP
dpc-5921	38	38	this	this	DET
dpc-5921	38	39	disease	disease	NOUN
dpc-5921	38	40	.	.	PUNCT
dpc-5921	39	1	the	the	DET
dpc-5921	39	2	aim	aim	NOUN
dpc-5921	39	3	of	of	ADP
dpc-5921	39	4	this	this	DET
dpc-5921	39	5	consensus	consensus	NOUN
dpc-5921	39	6	document	document	NOUN
dpc-5921	39	7	was	be	AUX
dpc-5921	39	8	to	to	PART
dpc-5921	39	9	deliver	deliver	VERB
dpc-5921	39	10	real	real	ADJ
dpc-5921	39	11	-	-	PUNCT
dpc-5921	39	12	world	world	NOUN
dpc-5921	39	13	guidance	guidance	NOUN
dpc-5921	39	14	on	on	ADP
dpc-5921	39	15	the	the	DET
dpc-5921	39	16	optimal	optimal	ADJ
dpc-5921	39	17	use	use	NOUN
dpc-5921	39	18	of	of	ADP
dpc-5921	39	19	tirbanibulin	tirbanibulin	PROPN
dpc-5921	39	20	in	in	ADP
dpc-5921	39	21	the	the	DET
dpc-5921	39	22	treatment	treatment	NOUN
dpc-5921	39	23	of	of	ADP
dpc-5921	39	24	ak	ak	PROPN
dpc-5921	39	25	throughout	throughout	ADP
dpc-5921	39	26	the	the	DET
dpc-5921	39	27	patient	patient	ADJ
dpc-5921	39	28	journey	journey	NOUN
dpc-5921	39	29	.	.	PUNCT
dpc-5921	40	1	methods	method	NOUN
dpc-5921	40	2	eleven	eleven	NUM
dpc-5921	40	3	dermatologists	dermatologist	NOUN
dpc-5921	40	4	with	with	ADP
dpc-5921	40	5	extensive	extensive	ADJ
dpc-5921	40	6	clinical	clinical	ADJ
dpc-5921	40	7	experience	experience	NOUN
dpc-5921	40	8	in	in	ADP
dpc-5921	40	9	the	the	DET
dpc-5921	40	10	treatment	treatment	NOUN
dpc-5921	40	11	of	of	ADP
dpc-5921	40	12	ak	ak	PROPN
dpc-5921	40	13	convened	convene	VERB
dpc-5921	40	14	to	to	PART
dpc-5921	40	15	discuss	discuss	VERB
dpc-5921	40	16	best	good	ADJ
dpc-5921	40	17	-	-	PUNCT
dpc-5921	40	18	practice	practice	NOUN
dpc-5921	40	19	patient	patient	NOUN
dpc-5921	40	20	management	management	NOUN
dpc-5921	40	21	and	and	CCONJ
dpc-5921	40	22	optimal	optimal	ADJ
dpc-5921	40	23	use	use	NOUN
dpc-5921	40	24	of	of	ADP
dpc-5921	40	25	tirbanibulin	tirbanibulin	PROPN
dpc-5921	40	26	based	base	VERB
dpc-5921	40	27	on	on	ADP
dpc-5921	40	28	the	the	DET
dpc-5921	40	29	presentation	presentation	NOUN
dpc-5921	40	30	of	of	ADP
dpc-5921	40	31	exemplary	exemplary	ADJ
dpc-5921	40	32	clinical	clinical	ADJ
dpc-5921	40	33	cases	case	NOUN
dpc-5921	40	34	and	and	CCONJ
dpc-5921	40	35	the	the	DET
dpc-5921	40	36	review	review	NOUN
dpc-5921	40	37	of	of	ADP
dpc-5921	40	38	relevant	relevant	ADJ
dpc-5921	40	39	literature	literature	NOUN
dpc-5921	40	40	data	data	PROPN
dpc-5921	40	41	.	.	PUNCT
dpc-5921	41	1	the	the	DET
dpc-5921	41	2	panel	panel	NOUN
dpc-5921	41	3	then	then	ADV
dpc-5921	41	4	developed	develop	VERB
dpc-5921	41	5	expert	expert	ADJ
dpc-5921	41	6	recommendations	recommendation	NOUN
dpc-5921	41	7	in	in	ADP
dpc-5921	41	8	the	the	DET
dpc-5921	41	9	form	form	NOUN
dpc-5921	41	10	of	of	ADP
dpc-5921	41	11	statements	statement	NOUN
dpc-5921	41	12	,	,	PUNCT
dpc-5921	41	13	subsequently	subsequently	ADV
dpc-5921	41	14	voted	vote	VERB
dpc-5921	41	15	on	on	ADP
dpc-5921	41	16	,	,	PUNCT
dpc-5921	41	17	related	relate	VERB
dpc-5921	41	18	to	to	ADP
dpc-5921	41	19	two	two	NUM
dpc-5921	41	20	areas	area	NOUN
dpc-5921	41	21	:	:	PUNCT
dpc-5921	41	22	1	1	X
dpc-5921	41	23	)	)	PUNCT
dpc-5921	41	24	clinical	clinical	ADJ
dpc-5921	41	25	assessment	assessment	NOUN
dpc-5921	41	26	of	of	ADP
dpc-5921	41	27	patients	patient	NOUN
dpc-5921	41	28	and	and	CCONJ
dpc-5921	41	29	real	real	ADJ
dpc-5921	41	30	-	-	PUNCT
dpc-5921	41	31	life	life	NOUN
dpc-5921	41	32	diagnostic	diagnostic	ADJ
dpc-5921	41	33	procedures	procedure	NOUN
dpc-5921	41	34	;	;	PUNCT
dpc-5921	41	35	2	2	X
dpc-5921	41	36	)	)	PUNCT
dpc-5921	41	37	key	key	ADJ
dpc-5921	41	38	aspects	aspect	NOUN
dpc-5921	41	39	of	of	ADP
dpc-5921	41	40	tirbanibulin	tirbanibulin	PROPN
dpc-5921	41	41	therapy	therapy	NOUN
dpc-5921	41	42	,	,	PUNCT
dpc-5921	41	43	including	include	VERB
dpc-5921	41	44	patient	patient	ADJ
dpc-5921	41	45	selection	selection	NOUN
dpc-5921	41	46	,	,	PUNCT
dpc-5921	41	47	treatment	treatment	NOUN
dpc-5921	41	48	modalities	modality	NOUN
dpc-5921	41	49	,	,	PUNCT
dpc-5921	41	50	and	and	CCONJ
dpc-5921	41	51	patient	patient	ADJ
dpc-5921	41	52	education	education	NOUN
dpc-5921	41	53	.	.	PUNCT
dpc-5921	42	1	only	only	ADV
dpc-5921	42	2	statements	statement	NOUN
dpc-5921	42	3	with	with	ADP
dpc-5921	42	4	a	a	DET
dpc-5921	42	5	consensus	consensus	NOUN
dpc-5921	42	6	of	of	ADP
dpc-5921	42	7	100	100	NUM
dpc-5921	42	8	%	%	NOUN
dpc-5921	42	9	were	be	AUX
dpc-5921	42	10	included	include	VERB
dpc-5921	42	11	.	.	PUNCT
dpc-5921	43	1	introduction	introduction	NOUN
dpc-5921	43	2	:	:	PUNCT
dpc-5921	43	3	tirbanibulin	tirbanibulin	PROPN
dpc-5921	43	4	,	,	PUNCT
dpc-5921	43	5	a	a	DET
dpc-5921	43	6	topical	topical	ADJ
dpc-5921	43	7	treatment	treatment	NOUN
dpc-5921	43	8	for	for	ADP
dpc-5921	43	9	actinic	actinic	ADJ
dpc-5921	43	10	keratosis	keratosis	NOUN
dpc-5921	43	11	(	(	PUNCT
dpc-5921	43	12	ak	ak	PROPN
dpc-5921	43	13	)	)	PUNCT
dpc-5921	43	14	with	with	ADP
dpc-5921	43	15	a	a	DET
dpc-5921	43	16	novel	novel	ADJ
dpc-5921	43	17	antiproliferative	antiproliferative	NOUN
dpc-5921	43	18	mechanism	mechanism	NOUN
dpc-5921	43	19	of	of	ADP
dpc-5921	43	20	action	action	NOUN
dpc-5921	43	21	,	,	PUNCT
dpc-5921	43	22	has	have	AUX
dpc-5921	43	23	demonstrated	demonstrate	VERB
dpc-5921	43	24	efficacy	efficacy	NOUN
dpc-5921	43	25	and	and	CCONJ
dpc-5921	43	26	a	a	DET
dpc-5921	43	27	favorable	favorable	ADJ
dpc-5921	43	28	tolerability	tolerability	NOUN
dpc-5921	43	29	profile	profile	NOUN
dpc-5921	43	30	in	in	ADP
dpc-5921	43	31	clinical	clinical	ADJ
dpc-5921	43	32	trials	trial	NOUN
dpc-5921	43	33	and	and	CCONJ
dpc-5921	43	34	real	real	ADJ
dpc-5921	43	35	-	-	PUNCT
dpc-5921	43	36	life	life	NOUN
dpc-5921	43	37	studies	study	NOUN
dpc-5921	43	38	.	.	PUNCT
dpc-5921	44	1	an	an	DET
dpc-5921	44	2	insight	insight	NOUN
dpc-5921	44	3	into	into	ADP
dpc-5921	44	4	best	good	ADJ
dpc-5921	44	5	-	-	PUNCT
dpc-5921	44	6	practice	practice	NOUN
dpc-5921	44	7	use	use	NOUN
dpc-5921	44	8	of	of	ADP
dpc-5921	44	9	tirbanibulin	tirbanibulin	PROPN
dpc-5921	44	10	in	in	ADP
dpc-5921	44	11	different	different	ADJ
dpc-5921	44	12	clinical	clinical	ADJ
dpc-5921	44	13	presentations	presentation	NOUN
dpc-5921	44	14	of	of	ADP
dpc-5921	44	15	ak	ak	PROPN
dpc-5921	44	16	would	would	AUX
dpc-5921	44	17	be	be	AUX
dpc-5921	44	18	useful	useful	ADJ
dpc-5921	44	19	.	.	PUNCT
dpc-5921	45	1	objectives	objective	NOUN
dpc-5921	45	2	:	:	PUNCT
dpc-5921	45	3	the	the	DET
dpc-5921	45	4	aim	aim	NOUN
dpc-5921	45	5	of	of	ADP
dpc-5921	45	6	this	this	DET
dpc-5921	45	7	article	article	NOUN
dpc-5921	45	8	was	be	AUX
dpc-5921	45	9	to	to	PART
dpc-5921	45	10	deliver	deliver	VERB
dpc-5921	45	11	advice	advice	NOUN
dpc-5921	45	12	,	,	PUNCT
dpc-5921	45	13	via	via	ADP
dpc-5921	45	14	expert	expert	ADJ
dpc-5921	45	15	consensus	consensus	NOUN
dpc-5921	45	16	,	,	PUNCT
dpc-5921	45	17	on	on	ADP
dpc-5921	45	18	the	the	DET
dpc-5921	45	19	optimal	optimal	ADJ
dpc-5921	45	20	use	use	NOUN
dpc-5921	45	21	of	of	ADP
dpc-5921	45	22	tirbanibulin	tirbanibulin	PROPN
dpc-5921	45	23	in	in	ADP
dpc-5921	45	24	the	the	DET
dpc-5921	45	25	real	real	ADJ
dpc-5921	45	26	-	-	PUNCT
dpc-5921	45	27	life	life	NOUN
dpc-5921	45	28	management	management	NOUN
dpc-5921	45	29	of	of	ADP
dpc-5921	45	30	ak	ak	PROPN
dpc-5921	45	31	.	.	PROPN
dpc-5921	45	32	methods	method	NOUN
dpc-5921	45	33	:	:	PUNCT
dpc-5921	45	34	a	a	DET
dpc-5921	45	35	panel	panel	NOUN
dpc-5921	45	36	of	of	ADP
dpc-5921	45	37	11	11	NUM
dpc-5921	45	38	dermatologists	dermatologist	NOUN
dpc-5921	45	39	with	with	ADP
dpc-5921	45	40	expertise	expertise	NOUN
dpc-5921	45	41	in	in	ADP
dpc-5921	45	42	the	the	DET
dpc-5921	45	43	treatment	treatment	NOUN
dpc-5921	45	44	of	of	ADP
dpc-5921	45	45	ak	ak	PROPN
dpc-5921	45	46	convened	convene	VERB
dpc-5921	45	47	to	to	PART
dpc-5921	45	48	develop	develop	VERB
dpc-5921	45	49	consensus	consensus	NOUN
dpc-5921	45	50	statements	statement	NOUN
dpc-5921	45	51	about	about	ADP
dpc-5921	45	52	key	key	ADJ
dpc-5921	45	53	aspects	aspect	NOUN
dpc-5921	45	54	of	of	ADP
dpc-5921	45	55	tirbanibulin	tirbanibulin	PROPN
dpc-5921	45	56	treatment	treatment	NOUN
dpc-5921	45	57	in	in	ADP
dpc-5921	45	58	ak	ak	PROPN
dpc-5921	45	59	patients	patient	NOUN
dpc-5921	45	60	based	base	VERB
dpc-5921	45	61	on	on	ADP
dpc-5921	45	62	selected	select	VERB
dpc-5921	45	63	literature	literature	NOUN
dpc-5921	45	64	data	datum	NOUN
dpc-5921	45	65	and	and	CCONJ
dpc-5921	45	66	on	on	ADP
dpc-5921	45	67	their	their	PRON
dpc-5921	45	68	own	own	ADJ
dpc-5921	45	69	clinical	clinical	ADJ
dpc-5921	45	70	experience	experience	NOUN
dpc-5921	45	71	.	.	PUNCT
dpc-5921	46	1	results	result	NOUN
dpc-5921	46	2	:	:	PUNCT
dpc-5921	46	3	two	two	NUM
dpc-5921	46	4	areas	area	NOUN
dpc-5921	46	5	were	be	AUX
dpc-5921	46	6	examined	examine	VERB
dpc-5921	46	7	and	and	CCONJ
dpc-5921	46	8	discussed	discuss	VERB
dpc-5921	46	9	:	:	PUNCT
dpc-5921	46	10	clinical	clinical	ADJ
dpc-5921	46	11	assessment	assessment	NOUN
dpc-5921	46	12	/	/	SYM
dpc-5921	46	13	diagnostic	diagnostic	ADJ
dpc-5921	46	14	procedures	procedure	NOUN
dpc-5921	46	15	and	and	CCONJ
dpc-5921	46	16	key	key	ADJ
dpc-5921	46	17	aspects	aspect	NOUN
dpc-5921	46	18	of	of	ADP
dpc-5921	46	19	tirbanibulin	tirbanibulin	PROPN
dpc-5921	46	20	therapy	therapy	NOUN
dpc-5921	46	21	.	.	PUNCT
dpc-5921	47	1	a	a	DET
dpc-5921	47	2	total	total	NOUN
dpc-5921	47	3	of	of	ADP
dpc-5921	47	4	19	19	NUM
dpc-5921	47	5	statements	statement	NOUN
dpc-5921	47	6	concerning	concern	VERB
dpc-5921	47	7	clinical	clinical	ADJ
dpc-5921	47	8	evaluation	evaluation	NOUN
dpc-5921	47	9	of	of	ADP
dpc-5921	47	10	ak	ak	PROPN
dpc-5921	47	11	patients	patient	NOUN
dpc-5921	47	12	,	,	PUNCT
dpc-5921	47	13	routine	routine	ADJ
dpc-5921	47	14	and	and	CCONJ
dpc-5921	47	15	advanced	advanced	ADJ
dpc-5921	47	16	diagnostic	diagnostic	ADJ
dpc-5921	47	17	instruments	instrument	NOUN
dpc-5921	47	18	,	,	PUNCT
dpc-5921	47	19	patient	patient	ADJ
dpc-5921	47	20	selection	selection	NOUN
dpc-5921	47	21	,	,	PUNCT
dpc-5921	47	22	treatment	treatment	NOUN
dpc-5921	47	23	modalities	modality	NOUN
dpc-5921	47	24	,	,	PUNCT
dpc-5921	47	25	and	and	CCONJ
dpc-5921	47	26	key	key	ADJ
dpc-5921	47	27	messages	message	NOUN
dpc-5921	47	28	for	for	ADP
dpc-5921	47	29	patient	patient	ADJ
dpc-5921	47	30	communication	communication	NOUN
dpc-5921	47	31	were	be	AUX
dpc-5921	47	32	drafted	draft	VERB
dpc-5921	47	33	and	and	CCONJ
dpc-5921	47	34	voted	vote	VERB
dpc-5921	47	35	on	on	ADP
dpc-5921	47	36	.	.	PUNCT
dpc-5921	48	1	conclusion	conclusion	NOUN
dpc-5921	48	2	:	:	PUNCT
dpc-5921	48	3	tirbanibulin	tirbanibulin	PROPN
dpc-5921	48	4	should	should	AUX
dpc-5921	48	5	be	be	AUX
dpc-5921	48	6	considered	consider	VERB
dpc-5921	48	7	as	as	ADP
dpc-5921	48	8	a	a	DET
dpc-5921	48	9	first	first	ADJ
dpc-5921	48	10	-	-	PUNCT
dpc-5921	48	11	line	line	NOUN
dpc-5921	48	12	option	option	NOUN
dpc-5921	48	13	for	for	ADP
dpc-5921	48	14	most	most	ADJ
dpc-5921	48	15	patients	patient	NOUN
dpc-5921	48	16	with	with	ADP
dpc-5921	48	17	ak	ak	PROPN
dpc-5921	48	18	owing	owe	VERB
dpc-5921	48	19	to	to	ADP
dpc-5921	48	20	its	its	PRON
dpc-5921	48	21	proven	prove	VERB
dpc-5921	48	22	efficacy	efficacy	NOUN
dpc-5921	48	23	,	,	PUNCT
dpc-5921	48	24	good	good	ADJ
dpc-5921	48	25	local	local	ADJ
dpc-5921	48	26	and	and	CCONJ
dpc-5921	48	27	systemic	systemic	ADJ
dpc-5921	48	28	tolerability	tolerability	NOUN
dpc-5921	48	29	,	,	PUNCT
dpc-5921	48	30	and	and	CCONJ
dpc-5921	48	31	a	a	DET
dpc-5921	48	32	short	short	ADJ
dpc-5921	48	33	treatment	treatment	NOUN
dpc-5921	48	34	regimen	regiman	NOUN
dpc-5921	48	35	of	of	ADP
dpc-5921	48	36	five	five	NUM
dpc-5921	48	37	days	day	NOUN
dpc-5921	48	38	.	.	PUNCT
dpc-5921	49	1	all	all	DET
dpc-5921	49	2	these	these	DET
dpc-5921	49	3	factors	factor	NOUN
dpc-5921	49	4	encourage	encourage	VERB
dpc-5921	49	5	patient	patient	ADJ
dpc-5921	49	6	acceptability	acceptability	NOUN
dpc-5921	49	7	and	and	CCONJ
dpc-5921	49	8	treatment	treatment	NOUN
dpc-5921	49	9	compliance	compliance	NOUN
dpc-5921	49	10	.	.	PUNCT
dpc-5921	50	1	the	the	DET
dpc-5921	50	2	favorable	favorable	ADJ
dpc-5921	50	3	safety	safety	NOUN
dpc-5921	50	4	profile	profile	NOUN
dpc-5921	50	5	and	and	CCONJ
dpc-5921	50	6	tolerability	tolerability	NOUN
dpc-5921	50	7	of	of	ADP
dpc-5921	50	8	tirbanibulin	tirbanibulin	PROPN
dpc-5921	50	9	also	also	ADV
dpc-5921	50	10	enable	enable	VERB
dpc-5921	50	11	flexible	flexible	ADJ
dpc-5921	50	12	therapeutic	therapeutic	ADJ
dpc-5921	50	13	schedules	schedule	NOUN
dpc-5921	50	14	,	,	PUNCT
dpc-5921	50	15	including	include	VERB
dpc-5921	50	16	repeated	repeat	VERB
dpc-5921	50	17	treatment	treatment	NOUN
dpc-5921	50	18	cycles	cycle	NOUN
dpc-5921	50	19	,	,	PUNCT
dpc-5921	50	20	if	if	SCONJ
dpc-5921	50	21	needed	need	VERB
dpc-5921	50	22	.	.	PUNCT
dpc-5921	51	1	abstract	abstract	ADJ
dpc-5921	51	2	review	review	NOUN
dpc-5921	51	3	|	|	ADV
dpc-5921	51	4	dermatol	dermatol	ADJ
dpc-5921	51	5	pract	pract	NOUN
dpc-5921	51	6	concept	concept	NOUN
dpc-5921	51	7	.	.	PUNCT
dpc-5921	52	1	2025;15(3):5921	2025;15(3):5921	NUM
dpc-5921	52	2	3	3	NUM
dpc-5921	52	3	clinical	clinical	ADJ
dpc-5921	52	4	assessment	assessment	NOUN
dpc-5921	52	5	and	and	CCONJ
dpc-5921	52	6	diagnostic	diagnostic	ADJ
dpc-5921	52	7	procedures	procedure	NOUN
dpc-5921	52	8	initial	initial	ADJ
dpc-5921	52	9	patient	patient	ADJ
dpc-5921	52	10	evaluation	evaluation	NOUN
dpc-5921	52	11	ak	ak	PROPN
dpc-5921	52	12	can	can	AUX
dpc-5921	52	13	have	have	AUX
dpc-5921	52	14	multiform	multiform	NOUN
dpc-5921	52	15	clinical	clinical	ADJ
dpc-5921	52	16	presentations	presentation	NOUN
dpc-5921	52	17	(	(	PUNCT
dpc-5921	52	18	including	include	VERB
dpc-5921	52	19	distinct	distinct	ADJ
dpc-5921	52	20	clinical	clinical	ADJ
dpc-5921	52	21	variants	variant	NOUN
dpc-5921	52	22	such	such	ADJ
dpc-5921	52	23	as	as	ADP
dpc-5921	52	24	pigmented	pigment	VERB
dpc-5921	52	25	,	,	PUNCT
dpc-5921	52	26	bowenoid	bowenoid	X
dpc-5921	52	27	,	,	PUNCT
dpc-5921	52	28	or	or	CCONJ
dpc-5921	52	29	lichenoid	lichenoid	PROPN
dpc-5921	52	30	ak	ak	PROPN
dpc-5921	52	31	)	)	PUNCT
dpc-5921	52	32	,	,	PUNCT
dpc-5921	52	33	with	with	ADP
dpc-5921	52	34	lesions	lesion	NOUN
dpc-5921	52	35	of	of	ADP
dpc-5921	52	36	variable	variable	ADJ
dpc-5921	52	37	thickness	thickness	NOUN
dpc-5921	52	38	and	and	CCONJ
dpc-5921	52	39	size	size	NOUN
dpc-5921	52	40	[	[	X
dpc-5921	52	41	1,12	1,12	NUM
dpc-5921	52	42	-	-	SYM
dpc-5921	52	43	14	14	NUM
dpc-5921	52	44	]	]	PUNCT
dpc-5921	52	45	.	.	PUNCT
dpc-5921	53	1	hyperkeratotic	hyperkeratotic	ADJ
dpc-5921	53	2	lesions	lesion	NOUN
dpc-5921	53	3	are	be	AUX
dpc-5921	53	4	best	well	ADV
dpc-5921	53	5	examined	examine	VERB
dpc-5921	53	6	after	after	ADP
dpc-5921	53	7	applying	apply	VERB
dpc-5921	53	8	an	an	DET
dpc-5921	53	9	ointment	ointment	NOUN
dpc-5921	53	10	containing	contain	VERB
dpc-5921	53	11	keratolytic	keratolytic	ADJ
dpc-5921	53	12	agents	agent	NOUN
dpc-5921	53	13	,	,	PUNCT
dpc-5921	53	14	since	since	SCONJ
dpc-5921	53	15	the	the	DET
dpc-5921	53	16	thick	thick	ADJ
dpc-5921	53	17	layer	layer	NOUN
dpc-5921	53	18	of	of	ADP
dpc-5921	53	19	scaly	scaly	NOUN
dpc-5921	53	20	tissue	tissue	NOUN
dpc-5921	53	21	may	may	AUX
dpc-5921	53	22	mask	mask	VERB
dpc-5921	53	23	the	the	DET
dpc-5921	53	24	real	real	ADJ
dpc-5921	53	25	aspect	aspect	NOUN
dpc-5921	53	26	of	of	ADP
dpc-5921	53	27	the	the	DET
dpc-5921	53	28	lesion	lesion	NOUN
dpc-5921	53	29	.	.	PUNCT
dpc-5921	54	1	ak	ak	PROPN
dpc-5921	54	2	lesions	lesion	NOUN
dpc-5921	54	3	are	be	AUX
dpc-5921	54	4	most	most	ADV
dpc-5921	54	5	visible	visible	ADJ
dpc-5921	54	6	on	on	ADP
dpc-5921	54	7	the	the	DET
dpc-5921	54	8	face	face	NOUN
dpc-5921	54	9	and	and	CCONJ
dpc-5921	54	10	scalp	scalp	NOUN
dpc-5921	54	11	but	but	CCONJ
dpc-5921	54	12	can	can	AUX
dpc-5921	54	13	also	also	ADV
dpc-5921	54	14	be	be	AUX
dpc-5921	54	15	found	find	VERB
dpc-5921	54	16	on	on	ADP
dpc-5921	54	17	the	the	DET
dpc-5921	54	18	limbs	limb	NOUN
dpc-5921	54	19	and	and	CCONJ
dpc-5921	54	20	trunk	trunk	NOUN
dpc-5921	54	21	.	.	PUNCT
dpc-5921	55	1	ak	ak	PROPN
dpc-5921	55	2	lesions	lesion	NOUN
dpc-5921	55	3	located	locate	VERB
dpc-5921	55	4	on	on	ADP
dpc-5921	55	5	the	the	DET
dpc-5921	55	6	lower	low	ADJ
dpc-5921	55	7	lip	lip	NOUN
dpc-5921	55	8	or	or	CCONJ
dpc-5921	55	9	ears	ear	NOUN
dpc-5921	55	10	are	be	AUX
dpc-5921	55	11	considered	consider	VERB
dpc-5921	55	12	high	high	ADJ
dpc-5921	55	13	-	-	PUNCT
dpc-5921	55	14	risk	risk	NOUN
dpc-5921	55	15	lesions	lesion	NOUN
dpc-5921	55	16	that	that	PRON
dpc-5921	55	17	are	be	AUX
dpc-5921	55	18	often	often	ADV
dpc-5921	55	19	resistant	resistant	ADJ
dpc-5921	55	20	to	to	ADP
dpc-5921	55	21	treatment	treatment	NOUN
dpc-5921	55	22	[	[	X
dpc-5921	55	23	1,9	1,9	NUM
dpc-5921	55	24	]	]	PUNCT
dpc-5921	55	25	.	.	PUNCT
dpc-5921	56	1	in	in	ADP
dpc-5921	56	2	addition	addition	NOUN
dpc-5921	56	3	to	to	ADP
dpc-5921	56	4	assessing	assess	VERB
dpc-5921	56	5	the	the	DET
dpc-5921	56	6	number	number	NOUN
dpc-5921	56	7	,	,	PUNCT
dpc-5921	56	8	aspect	aspect	NOUN
dpc-5921	56	9	,	,	PUNCT
dpc-5921	56	10	and	and	CCONJ
dpc-5921	56	11	location	location	NOUN
dpc-5921	56	12	of	of	ADP
dpc-5921	56	13	the	the	DET
dpc-5921	56	14	lesions	lesion	NOUN
dpc-5921	56	15	,	,	PUNCT
dpc-5921	56	16	it	it	PRON
dpc-5921	56	17	is	be	AUX
dpc-5921	56	18	important	important	ADJ
dpc-5921	56	19	to	to	PART
dpc-5921	56	20	accurately	accurately	ADV
dpc-5921	56	21	evaluate	evaluate	VERB
dpc-5921	56	22	the	the	DET
dpc-5921	56	23	photodamaged	photodamage	VERB
dpc-5921	56	24	skin	skin	NOUN
dpc-5921	56	25	surrounding	surround	VERB
dpc-5921	56	26	the	the	DET
dpc-5921	56	27	lesions	lesion	NOUN
dpc-5921	56	28	,	,	PUNCT
dpc-5921	56	29	since	since	SCONJ
dpc-5921	56	30	severe	severe	ADJ
dpc-5921	56	31	fc	fc	PROPN
dpc-5921	56	32	identifies	identify	VERB
dpc-5921	56	33	a	a	DET
dpc-5921	56	34	patient	patient	ADJ
dpc-5921	56	35	population	population	NOUN
dpc-5921	56	36	at	at	ADP
dpc-5921	56	37	high	high	ADJ
dpc-5921	56	38	risk	risk	NOUN
dpc-5921	56	39	for	for	ADP
dpc-5921	56	40	recurrence	recurrence	NOUN
dpc-5921	56	41	of	of	ADP
dpc-5921	56	42	ak	ak	PROPN
dpc-5921	56	43	and	and	CCONJ
dpc-5921	56	44	the	the	DET
dpc-5921	56	45	development	development	NOUN
dpc-5921	56	46	of	of	ADP
dpc-5921	56	47	multiple	multiple	ADJ
dpc-5921	56	48	csccs	csccs	NOUN
dpc-5921	56	49	that	that	PRON
dpc-5921	56	50	requires	require	VERB
dpc-5921	56	51	a	a	DET
dpc-5921	56	52	prompt	prompt	ADJ
dpc-5921	56	53	and	and	CCONJ
dpc-5921	56	54	aggressive	aggressive	ADJ
dpc-5921	56	55	therapeutic	therapeutic	ADJ
dpc-5921	56	56	approach	approach	NOUN
dpc-5921	56	57	[	[	X
dpc-5921	56	58	4,15,16	4,15,16	NUM
dpc-5921	56	59	]	]	PUNCT
dpc-5921	56	60	.	.	PUNCT
dpc-5921	57	1	there	there	PRON
dpc-5921	57	2	is	be	VERB
dpc-5921	57	3	evidence	evidence	NOUN
dpc-5921	57	4	from	from	ADP
dpc-5921	57	5	the	the	DET
dpc-5921	57	6	literature	literature	NOUN
dpc-5921	57	7	that	that	PRON
dpc-5921	57	8	several	several	ADJ
dpc-5921	57	9	uvb	uvb	ADJ
dpc-5921	57	10	-	-	PUNCT
dpc-5921	57	11	induced	induced	ADJ
dpc-5921	57	12	mutations	mutation	NOUN
dpc-5921	57	13	and	and	CCONJ
dpc-5921	57	14	gene	gene	NOUN
dpc-5921	57	15	expression	expression	NOUN
dpc-5921	57	16	alterations	alteration	NOUN
dpc-5921	57	17	that	that	PRON
dpc-5921	57	18	are	be	AUX
dpc-5921	57	19	frequently	frequently	ADV
dpc-5921	57	20	observed	observe	VERB
dpc-5921	57	21	in	in	ADP
dpc-5921	57	22	photodamaged	photodamage	VERB
dpc-5921	57	23	skin	skin	NOUN
dpc-5921	57	24	(	(	PUNCT
dpc-5921	57	25	e.g.	e.g.	ADV
dpc-5921	57	26	,	,	PUNCT
dpc-5921	57	27	deregulation	deregulation	NOUN
dpc-5921	57	28	of	of	ADP
dpc-5921	57	29	tumor	tumor	NOUN
dpc-5921	57	30	suppressor	suppressor	NOUN
dpc-5921	57	31	genes	gene	NOUN
dpc-5921	57	32	p53	p53	NOUN
dpc-5921	57	33	,	,	PUNCT
dpc-5921	57	34	cdkn2a	cdkn2a	PROPN
dpc-5921	57	35	and	and	CCONJ
dpc-5921	57	36	pten	pten	VERB
dpc-5921	57	37	,	,	PUNCT
dpc-5921	57	38	disruption	disruption	NOUN
dpc-5921	57	39	of	of	ADP
dpc-5921	57	40	the	the	DET
dpc-5921	57	41	raf-1	raf-1	ADJ
dpc-5921	57	42	/	/	SYM
dpc-5921	57	43	mer	mer	PROPN
dpc-5921	57	44	/	/	SYM
dpc-5921	57	45	erk	erk	PROPN
dpc-5921	57	46	cell	cell	NOUN
dpc-5921	57	47	survival	survival	NOUN
dpc-5921	57	48	pathway	pathway	NOUN
dpc-5921	57	49	)	)	PUNCT
dpc-5921	57	50	become	become	VERB
dpc-5921	57	51	increasingly	increasingly	ADV
dpc-5921	57	52	more	more	ADV
dpc-5921	57	53	severe	severe	ADJ
dpc-5921	57	54	in	in	ADP
dpc-5921	57	55	ak	ak	PROPN
dpc-5921	57	56	and	and	CCONJ
dpc-5921	57	57	scc	scc	PROPN
dpc-5921	57	58	,	,	PUNCT
dpc-5921	57	59	suggesting	suggest	VERB
dpc-5921	57	60	that	that	SCONJ
dpc-5921	57	61	photodamaged	photodamage	VERB
dpc-5921	57	62	skin	skin	NOUN
dpc-5921	57	63	,	,	PUNCT
dpc-5921	57	64	ak	ak	PROPN
dpc-5921	57	65	,	,	PUNCT
dpc-5921	57	66	and	and	CCONJ
dpc-5921	57	67	scc	scc	NOUN
dpc-5921	57	68	may	may	AUX
dpc-5921	57	69	be	be	AUX
dpc-5921	57	70	part	part	NOUN
dpc-5921	57	71	of	of	ADP
dpc-5921	57	72	a	a	DET
dpc-5921	57	73	disease	disease	NOUN
dpc-5921	57	74	continuum	continuum	ADJ
dpc-5921	57	75	that	that	PRON
dpc-5921	57	76	is	be	AUX
dpc-5921	57	77	manifested	manifest	VERB
dpc-5921	57	78	as	as	ADP
dpc-5921	57	79	fc	fc	PROPN
dpc-5921	57	80	[	[	X
dpc-5921	57	81	17,18	17,18	X
dpc-5921	57	82	]	]	PUNCT
dpc-5921	57	83	.	.	PUNCT
dpc-5921	58	1	despite	despite	SCONJ
dpc-5921	58	2	the	the	DET
dpc-5921	58	3	lack	lack	NOUN
dpc-5921	58	4	of	of	ADP
dpc-5921	58	5	a	a	DET
dpc-5921	58	6	clear	clear	ADJ
dpc-5921	58	7	and	and	CCONJ
dpc-5921	58	8	consistent	consistent	ADJ
dpc-5921	58	9	definition	definition	NOUN
dpc-5921	58	10	of	of	ADP
dpc-5921	58	11	fc	fc	PROPN
dpc-5921	58	12	,	,	PUNCT
dpc-5921	58	13	an	an	DET
dpc-5921	58	14	expert	expert	NOUN
dpc-5921	58	15	consensus	consensus	NOUN
dpc-5921	58	16	based	base	VERB
dpc-5921	58	17	on	on	ADP
dpc-5921	58	18	an	an	DET
dpc-5921	58	19	extensive	extensive	ADJ
dpc-5921	58	20	review	review	NOUN
dpc-5921	58	21	proposed	propose	VERB
dpc-5921	58	22	a	a	DET
dpc-5921	58	23	clinical	clinical	ADJ
dpc-5921	58	24	definition	definition	NOUN
dpc-5921	58	25	of	of	ADP
dpc-5921	58	26	fc	fc	PROPN
dpc-5921	58	27	as	as	ADP
dpc-5921	58	28	“	"	PUNCT
dpc-5921	58	29	the	the	DET
dpc-5921	58	30	anatomical	anatomical	ADJ
dpc-5921	58	31	area	area	NOUN
dpc-5921	58	32	with	with	ADP
dpc-5921	58	33	or	or	CCONJ
dpc-5921	58	34	adjacent	adjacent	ADJ
dpc-5921	58	35	to	to	ADP
dpc-5921	58	36	ak	ak	PROPN
dpc-5921	58	37	and	and	CCONJ
dpc-5921	58	38	visibly	visibly	ADV
dpc-5921	58	39	sun	sun	NOUN
dpc-5921	58	40	-	-	PUNCT
dpc-5921	58	41	damaged	damage	VERB
dpc-5921	58	42	skin	skin	NOUN
dpc-5921	58	43	identified	identify	VERB
dpc-5921	58	44	by	by	ADP
dpc-5921	58	45	at	at	ADV
dpc-5921	58	46	least	least	ADV
dpc-5921	58	47	two	two	NUM
dpc-5921	58	48	of	of	ADP
dpc-5921	58	49	the	the	DET
dpc-5921	58	50	following	follow	VERB
dpc-5921	58	51	signs	sign	NOUN
dpc-5921	58	52	:	:	PUNCT
dpc-5921	58	53	telangiectasia	telangiectasia	NOUN
dpc-5921	58	54	,	,	PUNCT
dpc-5921	58	55	atrophy	atrophy	NOUN
dpc-5921	58	56	,	,	PUNCT
dpc-5921	58	57	pigmentation	pigmentation	NOUN
dpc-5921	58	58	disorders	disorder	NOUN
dpc-5921	58	59	and	and	CCONJ
dpc-5921	58	60	sand	sand	NOUN
dpc-5921	58	61	paper	paper	NOUN
dpc-5921	58	62	-	-	PUNCT
dpc-5921	58	63	like	like	ADJ
dpc-5921	58	64	texture	texture	NOUN
dpc-5921	58	65	”	"	PUNCT
dpc-5921	59	1	[	[	X
dpc-5921	59	2	17	17	NUM
dpc-5921	59	3	]	]	PUNCT
dpc-5921	59	4	.	.	PUNCT
dpc-5921	60	1	even	even	ADV
dpc-5921	60	2	without	without	ADP
dpc-5921	60	3	diagnostic	diagnostic	ADJ
dpc-5921	60	4	instruments	instrument	NOUN
dpc-5921	60	5	,	,	PUNCT
dpc-5921	60	6	therefore	therefore	ADV
dpc-5921	60	7	,	,	PUNCT
dpc-5921	60	8	perilesional	perilesional	ADJ
dpc-5921	60	9	skin	skin	NOUN
dpc-5921	60	10	should	should	AUX
dpc-5921	60	11	be	be	AUX
dpc-5921	60	12	assessed	assess	VERB
dpc-5921	60	13	for	for	ADP
dpc-5921	60	14	visible	visible	ADJ
dpc-5921	60	15	signs	sign	NOUN
dpc-5921	60	16	of	of	ADP
dpc-5921	60	17	inflammation	inflammation	NOUN
dpc-5921	60	18	and	and	CCONJ
dpc-5921	60	19	uv	uv	NOUN
dpc-5921	60	20	damage	damage	NOUN
dpc-5921	60	21	.	.	PUNCT
dpc-5921	61	1	the	the	DET
dpc-5921	61	2	initial	initial	ADJ
dpc-5921	61	3	clinical	clinical	ADJ
dpc-5921	61	4	evaluation	evaluation	NOUN
dpc-5921	61	5	should	should	AUX
dpc-5921	61	6	also	also	ADV
dpc-5921	61	7	always	always	ADV
dpc-5921	61	8	consider	consider	VERB
dpc-5921	61	9	patient	patient	NOUN
dpc-5921	61	10	-	-	PUNCT
dpc-5921	61	11	specific	specific	ADJ
dpc-5921	61	12	factors	factor	NOUN
dpc-5921	61	13	such	such	ADJ
dpc-5921	61	14	as	as	ADP
dpc-5921	61	15	demographics	demographic	NOUN
dpc-5921	61	16	,	,	PUNCT
dpc-5921	61	17	fitzpatrick	fitzpatrick	PROPN
dpc-5921	61	18	type	type	PROPN
dpc-5921	61	19	,	,	PUNCT
dpc-5921	61	20	comorbidities	comorbiditie	NOUN
dpc-5921	61	21	,	,	PUNCT
dpc-5921	61	22	current	current	ADJ
dpc-5921	61	23	medications	medication	NOUN
dpc-5921	61	24	,	,	PUNCT
dpc-5921	61	25	past	past	ADP
dpc-5921	61	26	clinical	clinical	ADJ
dpc-5921	61	27	history	history	NOUN
dpc-5921	61	28	(	(	PUNCT
dpc-5921	61	29	especially	especially	ADV
dpc-5921	61	30	regarding	regard	VERB
dpc-5921	61	31	skin	skin	NOUN
dpc-5921	61	32	cancer	cancer	NOUN
dpc-5921	61	33	)	)	PUNCT
dpc-5921	61	34	,	,	PUNCT
dpc-5921	61	35	previous	previous	ADJ
dpc-5921	61	36	ak	ak	PROPN
dpc-5921	61	37	treatments	treatment	NOUN
dpc-5921	61	38	,	,	PUNCT
dpc-5921	61	39	and	and	CCONJ
dpc-5921	61	40	sun	sun	NOUN
dpc-5921	61	41	-	-	PUNCT
dpc-5921	61	42	protection	protection	NOUN
dpc-5921	61	43	behavior	behavior	NOUN
dpc-5921	61	44	.	.	PUNCT
dpc-5921	62	1	particular	particular	ADJ
dpc-5921	62	2	attention	attention	NOUN
dpc-5921	62	3	should	should	AUX
dpc-5921	62	4	be	be	AUX
dpc-5921	62	5	paid	pay	VERB
dpc-5921	62	6	to	to	ADP
dpc-5921	62	7	immunosuppression	immunosuppression	NOUN
dpc-5921	62	8	,	,	PUNCT
dpc-5921	62	9	as	as	ADP
dpc-5921	62	10	immunocompromised	immunocompromise	VERB
dpc-5921	62	11	patients	patient	NOUN
dpc-5921	62	12	,	,	PUNCT
dpc-5921	62	13	mainly	mainly	ADV
dpc-5921	62	14	organ	organ	NOUN
dpc-5921	62	15	transplant	transplant	NOUN
dpc-5921	62	16	recipients	recipient	NOUN
dpc-5921	62	17	,	,	PUNCT
dpc-5921	62	18	have	have	VERB
dpc-5921	62	19	a	a	DET
dpc-5921	62	20	greatly	greatly	ADV
dpc-5921	62	21	increased	increase	VERB
dpc-5921	62	22	risk	risk	NOUN
dpc-5921	62	23	of	of	ADP
dpc-5921	62	24	developing	develop	VERB
dpc-5921	62	25	more	more	ADV
dpc-5921	62	26	severe	severe	ADJ
dpc-5921	62	27	ak	ak	PROPN
dpc-5921	62	28	and	and	CCONJ
dpc-5921	62	29	scc	scc	PROPN
dpc-5921	62	30	,	,	PUNCT
dpc-5921	62	31	with	with	ADP
dpc-5921	62	32	worse	bad	ADJ
dpc-5921	62	33	treatment	treatment	NOUN
dpc-5921	62	34	outcomes	outcome	NOUN
dpc-5921	62	35	compared	compare	VERB
dpc-5921	62	36	to	to	ADP
dpc-5921	62	37	immunocompetent	immunocompetent	ADJ
dpc-5921	62	38	ak	ak	PROPN
dpc-5921	62	39	patients	patient	NOUN
dpc-5921	62	40	.	.	PUNCT
dpc-5921	63	1	in	in	ADP
dpc-5921	63	2	fact	fact	NOUN
dpc-5921	63	3	,	,	PUNCT
dpc-5921	63	4	immunocompromised	immunocompromise	VERB
dpc-5921	63	5	patients	patient	NOUN
dpc-5921	63	6	represent	represent	VERB
dpc-5921	63	7	a	a	DET
dpc-5921	63	8	distinct	distinct	ADJ
dpc-5921	63	9	population	population	NOUN
dpc-5921	63	10	requiring	require	VERB
dpc-5921	63	11	a	a	DET
dpc-5921	63	12	dedicated	dedicated	ADJ
dpc-5921	63	13	treatment	treatment	NOUN
dpc-5921	63	14	algorithm	algorithm	NOUN
dpc-5921	63	15	[	[	X
dpc-5921	63	16	1,19	1,19	X
dpc-5921	63	17	]	]	PUNCT
dpc-5921	63	18	.	.	PUNCT
dpc-5921	64	1	the	the	DET
dpc-5921	64	2	complexity	complexity	NOUN
dpc-5921	64	3	of	of	ADP
dpc-5921	64	4	ak	ak	PROPN
dpc-5921	64	5	features	feature	NOUN
dpc-5921	64	6	can	can	AUX
dpc-5921	64	7	not	not	PART
dpc-5921	64	8	be	be	AUX
dpc-5921	64	9	captured	capture	VERB
dpc-5921	64	10	by	by	ADP
dpc-5921	64	11	rigid	rigid	ADJ
dpc-5921	64	12	classification	classification	NOUN
dpc-5921	64	13	systems	system	NOUN
dpc-5921	64	14	.	.	PUNCT
dpc-5921	65	1	in	in	ADP
dpc-5921	65	2	the	the	DET
dpc-5921	65	3	olsen	olsen	NOUN
dpc-5921	65	4	clinical	clinical	ADJ
dpc-5921	65	5	classification	classification	NOUN
dpc-5921	65	6	scale	scale	NOUN
dpc-5921	65	7	,	,	PUNCT
dpc-5921	65	8	one	one	NUM
dpc-5921	65	9	of	of	ADP
dpc-5921	65	10	the	the	DET
dpc-5921	65	11	most	most	ADV
dpc-5921	65	12	commonly	commonly	ADV
dpc-5921	65	13	used	use	VERB
dpc-5921	65	14	parameters	parameter	NOUN
dpc-5921	65	15	for	for	ADP
dpc-5921	65	16	assessing	assess	VERB
dpc-5921	65	17	ak	ak	PROPN
dpc-5921	65	18	severity	severity	NOUN
dpc-5921	65	19	,	,	PUNCT
dpc-5921	65	20	single	single	ADJ
dpc-5921	65	21	lesions	lesion	NOUN
dpc-5921	65	22	are	be	AUX
dpc-5921	65	23	graded	grade	VERB
dpc-5921	65	24	based	base	VERB
dpc-5921	65	25	on	on	ADP
dpc-5921	65	26	their	their	PRON
dpc-5921	65	27	thickness	thickness	NOUN
dpc-5921	66	1	[	[	X
dpc-5921	66	2	20	20	NUM
dpc-5921	66	3	]	]	PUNCT
dpc-5921	66	4	.	.	PUNCT
dpc-5921	67	1	the	the	DET
dpc-5921	67	2	olsen	olsen	NOUN
dpc-5921	67	3	scale	scale	NOUN
dpc-5921	67	4	has	have	AUX
dpc-5921	67	5	been	be	AUX
dpc-5921	67	6	used	use	VERB
dpc-5921	67	7	in	in	ADP
dpc-5921	67	8	most	most	ADJ
dpc-5921	67	9	clinical	clinical	ADJ
dpc-5921	67	10	trials	trial	NOUN
dpc-5921	67	11	of	of	ADP
dpc-5921	67	12	ak	ak	PROPN
dpc-5921	67	13	treatments	treatment	NOUN
dpc-5921	67	14	and	and	CCONJ
dpc-5921	67	15	is	be	AUX
dpc-5921	67	16	a	a	DET
dpc-5921	67	17	valuable	valuable	ADJ
dpc-5921	67	18	tool	tool	NOUN
dpc-5921	67	19	for	for	ADP
dpc-5921	67	20	the	the	DET
dpc-5921	67	21	assessment	assessment	NOUN
dpc-5921	67	22	of	of	ADP
dpc-5921	67	23	individual	individual	ADJ
dpc-5921	67	24	lesions	lesion	NOUN
dpc-5921	67	25	,	,	PUNCT
dpc-5921	67	26	but	but	CCONJ
dpc-5921	67	27	it	it	PRON
dpc-5921	67	28	does	do	AUX
dpc-5921	67	29	not	not	PART
dpc-5921	67	30	consider	consider	VERB
dpc-5921	67	31	the	the	DET
dpc-5921	67	32	severity	severity	NOUN
dpc-5921	67	33	of	of	ADP
dpc-5921	67	34	fc	fc	PROPN
dpc-5921	67	35	.	.	PUNCT
dpc-5921	68	1	for	for	ADP
dpc-5921	68	2	a	a	DET
dpc-5921	68	3	more	more	ADV
dpc-5921	68	4	complete	complete	ADJ
dpc-5921	68	5	assessment	assessment	NOUN
dpc-5921	68	6	of	of	ADP
dpc-5921	68	7	ak	ak	PROPN
dpc-5921	68	8	severity	severity	NOUN
dpc-5921	68	9	that	that	PRON
dpc-5921	68	10	includes	include	VERB
dpc-5921	68	11	fc	fc	PROPN
dpc-5921	68	12	,	,	PUNCT
dpc-5921	68	13	the	the	DET
dpc-5921	68	14	actinic	actinic	ADJ
dpc-5921	68	15	keratosis	keratosis	NOUN
dpc-5921	68	16	field	field	NOUN
dpc-5921	68	17	assessment	assessment	NOUN
dpc-5921	68	18	scale	scale	NOUN
dpc-5921	68	19	(	(	PUNCT
dpc-5921	68	20	ak	ak	NOUN
dpc-5921	68	21	-	-	PUNCT
dpc-5921	68	22	fas	fas	NOUN
dpc-5921	68	23	)	)	PUNCT
dpc-5921	68	24	is	be	AUX
dpc-5921	68	25	preferable	preferable	ADJ
dpc-5921	68	26	[	[	X
dpc-5921	68	27	15	15	NUM
dpc-5921	68	28	]	]	PUNCT
dpc-5921	68	29	.	.	PUNCT
dpc-5921	69	1	this	this	DET
dpc-5921	69	2	validated	validate	VERB
dpc-5921	69	3	tool	tool	NOUN
dpc-5921	69	4	,	,	PUNCT
dpc-5921	69	5	a	a	DET
dpc-5921	69	6	4	4	NUM
dpc-5921	69	7	-	-	PUNCT
dpc-5921	69	8	grade	grade	NOUN
dpc-5921	69	9	scale	scale	NOUN
dpc-5921	69	10	which	which	PRON
dpc-5921	69	11	evaluates	evaluate	VERB
dpc-5921	69	12	ak	ak	PROPN
dpc-5921	69	13	area	area	PROPN
dpc-5921	69	14	,	,	PUNCT
dpc-5921	69	15	hyperkeratosis	hyperkeratosis	NOUN
dpc-5921	69	16	,	,	PUNCT
dpc-5921	69	17	and	and	CCONJ
dpc-5921	69	18	sun	sun	NOUN
dpc-5921	69	19	damage	damage	NOUN
dpc-5921	69	20	,	,	PUNCT
dpc-5921	69	21	provides	provide	VERB
dpc-5921	69	22	objective	objective	ADJ
dpc-5921	69	23	and	and	CCONJ
dpc-5921	69	24	clinically	clinically	ADV
dpc-5921	69	25	relevant	relevant	ADJ
dpc-5921	69	26	information	information	NOUN
dpc-5921	69	27	and	and	CCONJ
dpc-5921	69	28	is	be	AUX
dpc-5921	69	29	easy	easy	ADJ
dpc-5921	69	30	to	to	PART
dpc-5921	69	31	use	use	VERB
dpc-5921	69	32	in	in	ADP
dpc-5921	69	33	routine	routine	ADJ
dpc-5921	69	34	practice	practice	NOUN
dpc-5921	69	35	.	.	PUNCT
dpc-5921	70	1	instrumental	instrumental	ADJ
dpc-5921	70	2	diagnostic	diagnostic	ADJ
dpc-5921	70	3	techniques	technique	NOUN
dpc-5921	70	4	and	and	CCONJ
dpc-5921	70	5	histopathology	histopathology	NOUN
dpc-5921	70	6	dermatoscopy	dermatoscopy	NOUN
dpc-5921	70	7	is	be	AUX
dpc-5921	70	8	an	an	DET
dpc-5921	70	9	easy	easy	ADJ
dpc-5921	70	10	-	-	PUNCT
dpc-5921	70	11	to	to	ADP
dpc-5921	70	12	-	-	PUNCT
dpc-5921	70	13	use	use	VERB
dpc-5921	70	14	,	,	PUNCT
dpc-5921	70	15	readily	readily	ADV
dpc-5921	70	16	available	available	ADJ
dpc-5921	70	17	,	,	PUNCT
dpc-5921	70	18	non	non	X
dpc-5921	70	19	invasive	invasive	ADJ
dpc-5921	70	20	technique	technique	NOUN
dpc-5921	70	21	that	that	PRON
dpc-5921	70	22	should	should	AUX
dpc-5921	70	23	always	always	ADV
dpc-5921	70	24	be	be	AUX
dpc-5921	70	25	part	part	NOUN
dpc-5921	70	26	of	of	ADP
dpc-5921	70	27	the	the	DET
dpc-5921	70	28	clinical	clinical	ADJ
dpc-5921	70	29	assessment	assessment	NOUN
dpc-5921	70	30	of	of	ADP
dpc-5921	70	31	ak	ak	PROPN
dpc-5921	70	32	.	.	PROPN
dpc-5921	70	33	dermatoscopy	dermatoscopy	NOUN
dpc-5921	70	34	enables	enable	VERB
dpc-5921	70	35	clinicians	clinician	NOUN
dpc-5921	70	36	to	to	PART
dpc-5921	70	37	visualize	visualize	VERB
dpc-5921	70	38	typical	typical	ADJ
dpc-5921	70	39	clinical	clinical	ADJ
dpc-5921	70	40	aspects	aspect	NOUN
dpc-5921	70	41	of	of	ADP
dpc-5921	70	42	ak	ak	PROPN
dpc-5921	70	43	(	(	PUNCT
dpc-5921	70	44	e.g.	e.g.	ADV
dpc-5921	70	45	,	,	PUNCT
dpc-5921	70	46	erythematous	erythematous	ADJ
dpc-5921	70	47	pseudonetwork	pseudonetwork	NOUN
dpc-5921	70	48	,	,	PUNCT
dpc-5921	70	49	‘	'	PUNCT
dpc-5921	70	50	strawberry	strawberry	NOUN
dpc-5921	70	51	pattern	pattern	NOUN
dpc-5921	70	52	’	'	PUNCT
dpc-5921	70	53	,	,	PUNCT
dpc-5921	70	54	large	large	ADJ
dpc-5921	70	55	white	white	ADJ
dpc-5921	70	56	follicles	follicle	NOUN
dpc-5921	70	57	,	,	PUNCT
dpc-5921	70	58	and	and	CCONJ
dpc-5921	70	59	yellow	yellow	ADJ
dpc-5921	70	60	or	or	CCONJ
dpc-5921	70	61	whitish	whitish	ADJ
dpc-5921	70	62	scales	scale	NOUN
dpc-5921	70	63	)	)	PUNCT
dpc-5921	70	64	,	,	PUNCT
dpc-5921	70	65	and	and	CCONJ
dpc-5921	70	66	thus	thus	ADV
dpc-5921	70	67	it	it	PRON
dpc-5921	70	68	helps	help	VERB
dpc-5921	70	69	in	in	ADP
dpc-5921	70	70	the	the	DET
dpc-5921	70	71	differential	differential	ADJ
dpc-5921	70	72	diagnosis	diagnosis	NOUN
dpc-5921	70	73	of	of	ADP
dpc-5921	70	74	ak	ak	PROPN
dpc-5921	70	75	and	and	CCONJ
dpc-5921	70	76	superficial	superficial	ADJ
dpc-5921	70	77	basal	basal	NOUN
dpc-5921	70	78	cell	cell	NOUN
dpc-5921	70	79	carcinoma	carcinoma	NOUN
dpc-5921	70	80	,	,	PUNCT
dpc-5921	70	81	lentigo	lentigo	ADJ
dpc-5921	70	82	melanoma	melanoma	NOUN
dpc-5921	70	83	,	,	PUNCT
dpc-5921	70	84	irritated	irritated	ADJ
dpc-5921	70	85	seborrheic	seborrheic	ADJ
dpc-5921	70	86	keratosis	keratosis	NOUN
dpc-5921	70	87	,	,	PUNCT
dpc-5921	70	88	or	or	CCONJ
dpc-5921	70	89	other	other	ADJ
dpc-5921	70	90	inflammatory	inflammatory	ADJ
dpc-5921	70	91	skin	skin	NOUN
dpc-5921	70	92	diseases	disease	NOUN
dpc-5921	70	93	[	[	X
dpc-5921	70	94	1,14,21	1,14,21	NUM
dpc-5921	70	95	]	]	PUNCT
dpc-5921	70	96	.	.	PUNCT
dpc-5921	71	1	dermatoscopy	dermatoscopy	VERB
dpc-5921	71	2	also	also	ADV
dpc-5921	71	3	plays	play	VERB
dpc-5921	71	4	an	an	DET
dpc-5921	71	5	important	important	ADJ
dpc-5921	71	6	role	role	NOUN
dpc-5921	71	7	in	in	ADP
dpc-5921	71	8	monitoring	monitor	VERB
dpc-5921	71	9	treatment	treatment	NOUN
dpc-5921	71	10	response	response	NOUN
dpc-5921	71	11	and	and	CCONJ
dpc-5921	71	12	identifying	identify	VERB
dpc-5921	71	13	early	early	ADJ
dpc-5921	71	14	signs	sign	NOUN
dpc-5921	71	15	of	of	ADP
dpc-5921	71	16	invasive	invasive	ADJ
dpc-5921	71	17	scc	scc	NOUN
dpc-5921	71	18	such	such	DET
dpc-5921	71	19	the	the	DET
dpc-5921	71	20	presence	presence	NOUN
dpc-5921	71	21	of	of	ADP
dpc-5921	71	22	peripheral	peripheral	ADJ
dpc-5921	71	23	radial	radial	ADJ
dpc-5921	71	24	lines	line	NOUN
dpc-5921	71	25	or	or	CCONJ
dpc-5921	71	26	vessels	vessel	NOUN
dpc-5921	71	27	in	in	ADP
dpc-5921	71	28	the	the	DET
dpc-5921	71	29	context	context	NOUN
dpc-5921	71	30	of	of	ADP
dpc-5921	71	31	typical	typical	ADJ
dpc-5921	71	32	ak	ak	PROPN
dpc-5921	71	33	signs	sign	NOUN
dpc-5921	71	34	[	[	X
dpc-5921	71	35	14,21	14,21	NUM
dpc-5921	71	36	]	]	PUNCT
dpc-5921	71	37	.	.	PUNCT
dpc-5921	72	1	histopathological	histopathological	ADJ
dpc-5921	72	2	examination	examination	NOUN
dpc-5921	72	3	of	of	ADP
dpc-5921	72	4	biopsy	biopsy	NOUN
dpc-5921	72	5	specimens	specimen	NOUN
dpc-5921	72	6	should	should	AUX
dpc-5921	72	7	be	be	AUX
dpc-5921	72	8	carried	carry	VERB
dpc-5921	72	9	out	out	ADP
dpc-5921	72	10	when	when	SCONJ
dpc-5921	72	11	atypical	atypical	ADJ
dpc-5921	72	12	lesions	lesion	NOUN
dpc-5921	72	13	are	be	AUX
dpc-5921	72	14	present	present	ADJ
dpc-5921	72	15	,	,	PUNCT
dpc-5921	72	16	especially	especially	ADV
dpc-5921	72	17	if	if	SCONJ
dpc-5921	72	18	they	they	PRON
dpc-5921	72	19	show	show	VERB
dpc-5921	72	20	features	feature	NOUN
dpc-5921	72	21	that	that	PRON
dpc-5921	72	22	may	may	AUX
dpc-5921	72	23	suggest	suggest	VERB
dpc-5921	72	24	a	a	DET
dpc-5921	72	25	diagnosis	diagnosis	NOUN
dpc-5921	72	26	of	of	ADP
dpc-5921	72	27	cscc	cscc	ADJ
dpc-5921	72	28	or	or	CCONJ
dpc-5921	72	29	other	other	ADJ
dpc-5921	72	30	types	type	NOUN
dpc-5921	72	31	of	of	ADP
dpc-5921	72	32	skin	skin	NOUN
dpc-5921	72	33	cancer	cancer	NOUN
dpc-5921	72	34	[	[	X
dpc-5921	72	35	1	1	NUM
dpc-5921	72	36	]	]	PUNCT
dpc-5921	72	37	.	.	PUNCT
dpc-5921	73	1	although	although	SCONJ
dpc-5921	73	2	more	more	ADV
dpc-5921	73	3	advanced	advanced	ADJ
dpc-5921	73	4	imaging	imaging	NOUN
dpc-5921	73	5	techniques	technique	NOUN
dpc-5921	73	6	,	,	PUNCT
dpc-5921	73	7	such	such	ADJ
dpc-5921	73	8	as	as	ADP
dpc-5921	73	9	reflectance	reflectance	NOUN
dpc-5921	73	10	confocal	confocal	ADJ
dpc-5921	73	11	microscopy	microscopy	NOUN
dpc-5921	73	12	(	(	PUNCT
dpc-5921	73	13	rcm	rcm	PROPN
dpc-5921	73	14	)	)	PUNCT
dpc-5921	73	15	,	,	PUNCT
dpc-5921	73	16	optical	optical	ADJ
dpc-5921	73	17	coherence	coherence	NOUN
dpc-5921	73	18	tomography	tomography	NOUN
dpc-5921	73	19	(	(	PUNCT
dpc-5921	73	20	oct	oct	PROPN
dpc-5921	73	21	)	)	PUNCT
dpc-5921	73	22	,	,	PUNCT
dpc-5921	73	23	and	and	CCONJ
dpc-5921	73	24	line	line	NOUN
dpc-5921	73	25	-	-	PUNCT
dpc-5921	73	26	field	field	NOUN
dpc-5921	73	27	confocal	confocal	ADJ
dpc-5921	73	28	oct	oct	PROPN
dpc-5921	73	29	(	(	PUNCT
dpc-5921	73	30	lc	lc	PROPN
dpc-5921	73	31	-	-	PUNCT
dpc-5921	73	32	oct	oct	NOUN
dpc-5921	73	33	)	)	PUNCT
dpc-5921	73	34	,	,	PUNCT
dpc-5921	73	35	are	be	AUX
dpc-5921	73	36	not	not	PART
dpc-5921	73	37	part	part	NOUN
dpc-5921	73	38	of	of	ADP
dpc-5921	73	39	the	the	DET
dpc-5921	73	40	routine	routine	ADJ
dpc-5921	73	41	clinical	clinical	ADJ
dpc-5921	73	42	assessment	assessment	NOUN
dpc-5921	73	43	,	,	PUNCT
dpc-5921	73	44	when	when	SCONJ
dpc-5921	73	45	available	available	ADJ
dpc-5921	73	46	,	,	PUNCT
dpc-5921	73	47	they	they	PRON
dpc-5921	73	48	can	can	AUX
dpc-5921	73	49	provide	provide	VERB
dpc-5921	73	50	useful	useful	ADJ
dpc-5921	73	51	information	information	NOUN
dpc-5921	73	52	in	in	ADP
dpc-5921	73	53	specific	specific	ADJ
dpc-5921	73	54	cases	case	NOUN
dpc-5921	73	55	.	.	PUNCT
dpc-5921	74	1	overall	overall	ADV
dpc-5921	74	2	,	,	PUNCT
dpc-5921	74	3	these	these	DET
dpc-5921	74	4	non	non	ADJ
dpc-5921	74	5	-	-	ADJ
dpc-5921	74	6	invasive	invasive	ADJ
dpc-5921	74	7	techniques	technique	NOUN
dpc-5921	74	8	help	help	AUX
dpc-5921	74	9	increase	increase	VERB
dpc-5921	74	10	diagnostic	diagnostic	ADJ
dpc-5921	74	11	accuracy	accuracy	NOUN
dpc-5921	74	12	and	and	CCONJ
dpc-5921	74	13	provide	provide	VERB
dpc-5921	74	14	additional	additional	ADJ
dpc-5921	74	15	information	information	NOUN
dpc-5921	74	16	on	on	ADP
dpc-5921	74	17	the	the	DET
dpc-5921	74	18	microenvironment	microenvironment	NOUN
dpc-5921	74	19	of	of	ADP
dpc-5921	74	20	ak	ak	PROPN
dpc-5921	74	21	lesions	lesion	NOUN
dpc-5921	74	22	,	,	PUNCT
dpc-5921	74	23	enabling	enable	VERB
dpc-5921	74	24	detection	detection	NOUN
dpc-5921	74	25	of	of	ADP
dpc-5921	74	26	subclinical	subclinical	ADJ
dpc-5921	74	27	changes	change	NOUN
dpc-5921	74	28	[	[	X
dpc-5921	74	29	1,14,22,23	1,14,22,23	NUM
dpc-5921	74	30	]	]	PUNCT
dpc-5921	74	31	.	.	PUNCT
dpc-5921	75	1	they	they	PRON
dpc-5921	75	2	also	also	ADV
dpc-5921	75	3	play	play	VERB
dpc-5921	75	4	an	an	DET
dpc-5921	75	5	important	important	ADJ
dpc-5921	75	6	role	role	NOUN
dpc-5921	75	7	in	in	ADP
dpc-5921	75	8	monitoring	monitor	VERB
dpc-5921	75	9	treatment	treatment	NOUN
dpc-5921	75	10	response	response	NOUN
dpc-5921	75	11	,	,	PUNCT
dpc-5921	75	12	thus	thus	ADV
dpc-5921	75	13	optimizing	optimize	VERB
dpc-5921	75	14	patient	patient	ADJ
dpc-5921	75	15	management	management	NOUN
dpc-5921	75	16	[	[	X
dpc-5921	75	17	1,14,24,25	1,14,24,25	NUM
dpc-5921	75	18	]	]	X
dpc-5921	75	19	(	(	PUNCT
dpc-5921	75	20	figure	figure	NOUN
dpc-5921	75	21	1	1	NUM
dpc-5921	75	22	)	)	PUNCT
dpc-5921	75	23	.	.	PUNCT
dpc-5921	76	1	expert	expert	ADJ
dpc-5921	76	2	consensus	consensus	NOUN
dpc-5921	76	3	statements	statement	NOUN
dpc-5921	76	4	with	with	ADP
dpc-5921	76	5	recommendations	recommendation	NOUN
dpc-5921	76	6	on	on	ADP
dpc-5921	76	7	clinical	clinical	ADJ
dpc-5921	76	8	assessment	assessment	NOUN
dpc-5921	76	9	and	and	CCONJ
dpc-5921	76	10	diagnosis	diagnosis	NOUN
dpc-5921	76	11	of	of	ADP
dpc-5921	76	12	ak	ak	PROPN
dpc-5921	76	13	are	be	AUX
dpc-5921	76	14	reported	report	VERB
dpc-5921	76	15	in	in	ADP
dpc-5921	76	16	table	table	NOUN
dpc-5921	76	17	1(a	1(a	NUM
dpc-5921	76	18	)	)	PUNCT
dpc-5921	76	19	.	.	PUNCT
dpc-5921	77	1	treatment	treatment	NOUN
dpc-5921	77	2	of	of	ADP
dpc-5921	77	3	ak	ak	PROPN
dpc-5921	77	4	with	with	ADP
dpc-5921	77	5	tirbanibulin	tirbanibulin	PROPN
dpc-5921	77	6	ak	ak	PROPN
dpc-5921	77	7	is	be	AUX
dpc-5921	77	8	a	a	DET
dpc-5921	77	9	chronic	chronic	ADJ
dpc-5921	77	10	disease	disease	NOUN
dpc-5921	77	11	that	that	PRON
dpc-5921	77	12	requires	require	VERB
dpc-5921	77	13	regular	regular	ADJ
dpc-5921	77	14	surveillance	surveillance	NOUN
dpc-5921	77	15	and	and	CCONJ
dpc-5921	77	16	long	long	ADJ
dpc-5921	77	17	-	-	PUNCT
dpc-5921	77	18	term	term	NOUN
dpc-5921	77	19	,	,	PUNCT
dpc-5921	77	20	personalized	personalized	ADJ
dpc-5921	77	21	management	management	NOUN
dpc-5921	77	22	based	base	VERB
dpc-5921	77	23	on	on	ADP
dpc-5921	77	24	prevention	prevention	NOUN
dpc-5921	77	25	(	(	PUNCT
dpc-5921	77	26	i.e.	i.e.	X
dpc-5921	77	27	,	,	PUNCT
dpc-5921	77	28	photoprotection	photoprotection	NOUN
dpc-5921	77	29	)	)	PUNCT
dpc-5921	77	30	and	and	CCONJ
dpc-5921	77	31	therapy	therapy	NOUN
dpc-5921	77	32	of	of	ADP
dpc-5921	77	33	both	both	CCONJ
dpc-5921	77	34	visible	visible	ADJ
dpc-5921	77	35	lesions	lesion	NOUN
dpc-5921	77	36	and	and	CCONJ
dpc-5921	77	37	fc	fc	NOUN
dpc-5921	77	38	;	;	PUNCT
dpc-5921	77	39	compliance	compliance	NOUN
dpc-5921	77	40	is	be	AUX
dpc-5921	77	41	crucial	crucial	ADJ
dpc-5921	77	42	to	to	ADP
dpc-5921	77	43	treatment	treatment	NOUN
dpc-5921	77	44	success	success	NOUN
dpc-5921	77	45	.	.	PUNCT
dpc-5921	78	1	in	in	ADP
dpc-5921	78	2	the	the	DET
dpc-5921	78	3	natural	natural	ADJ
dpc-5921	78	4	history	history	NOUN
dpc-5921	78	5	of	of	ADP
dpc-5921	78	6	the	the	DET
dpc-5921	78	7	disease	disease	NOUN
dpc-5921	78	8	,	,	PUNCT
dpc-5921	78	9	the	the	DET
dpc-5921	78	10	evolution	evolution	NOUN
dpc-5921	78	11	of	of	ADP
dpc-5921	78	12	ak	ak	PROPN
dpc-5921	78	13	lesions	lesion	NOUN
dpc-5921	78	14	(	(	PUNCT
dpc-5921	78	15	e.g.	e.g.	ADV
dpc-5921	78	16	,	,	PUNCT
dpc-5921	78	17	persistence	persistence	NOUN
dpc-5921	78	18	,	,	PUNCT
dpc-5921	78	19	resolution	resolution	NOUN
dpc-5921	78	20	,	,	PUNCT
dpc-5921	78	21	or	or	CCONJ
dpc-5921	78	22	progression	progression	NOUN
dpc-5921	78	23	to	to	PART
dpc-5921	78	24	cscc	cscc	VERB
dpc-5921	78	25	)	)	PUNCT
dpc-5921	78	26	is	be	AUX
dpc-5921	78	27	unpredictable	unpredictable	ADJ
dpc-5921	78	28	,	,	PUNCT
dpc-5921	78	29	and	and	CCONJ
dpc-5921	78	30	disease	disease	NOUN
dpc-5921	78	31	recurrence	recurrence	NOUN
dpc-5921	78	32	is	be	AUX
dpc-5921	78	33	the	the	DET
dpc-5921	78	34	norm	norm	NOUN
dpc-5921	78	35	owing	owe	VERB
dpc-5921	78	36	to	to	ADP
dpc-5921	78	37	the	the	DET
dpc-5921	78	38	continuous	continuous	ADJ
dpc-5921	78	39	presence	presence	NOUN
dpc-5921	78	40	of	of	ADP
dpc-5921	78	41	mutagenic	mutagenic	ADJ
dpc-5921	78	42	disease	disease	NOUN
dpc-5921	78	43	drivers	driver	NOUN
dpc-5921	78	44	induced	induce	VERB
dpc-5921	78	45	by	by	ADP
dpc-5921	78	46	uv	uv	NOUN
dpc-5921	78	47	radiation	radiation	NOUN
dpc-5921	79	1	[	[	X
dpc-5921	79	2	2,4,13,26	2,4,13,26	NOUN
dpc-5921	79	3	]	]	PUNCT
dpc-5921	79	4	.	.	PUNCT
dpc-5921	80	1	the	the	DET
dpc-5921	80	2	main	main	ADJ
dpc-5921	80	3	objective	objective	NOUN
dpc-5921	80	4	of	of	ADP
dpc-5921	80	5	ak	ak	PROPN
dpc-5921	80	6	therapy	therapy	NOUN
dpc-5921	80	7	4	4	NUM
dpc-5921	80	8	review	review	NOUN
dpc-5921	80	9	|	|	ADV
dpc-5921	80	10	dermatol	dermatol	ADJ
dpc-5921	80	11	pract	pract	NOUN
dpc-5921	80	12	concept	concept	NOUN
dpc-5921	80	13	.	.	PUNCT
dpc-5921	81	1	2025;15(3):5921	2025;15(3):5921	NUM
dpc-5921	81	2	a	a	DET
dpc-5921	81	3	topical	topical	ADJ
dpc-5921	81	4	ointment	ointment	NOUN
dpc-5921	81	5	approved	approve	VERB
dpc-5921	81	6	in	in	ADP
dpc-5921	81	7	the	the	DET
dpc-5921	81	8	us	us	PROPN
dpc-5921	81	9	(	(	PUNCT
dpc-5921	81	10	2020	2020	NUM
dpc-5921	81	11	)	)	PUNCT
dpc-5921	81	12	and	and	CCONJ
dpc-5921	81	13	europe	europe	PROPN
dpc-5921	81	14	(	(	PUNCT
dpc-5921	81	15	2021	2021	NUM
dpc-5921	81	16	)	)	PUNCT
dpc-5921	81	17	for	for	ADP
dpc-5921	81	18	the	the	DET
dpc-5921	81	19	treatment	treatment	NOUN
dpc-5921	81	20	of	of	ADP
dpc-5921	81	21	ak	ak	PROPN
dpc-5921	81	22	on	on	ADP
dpc-5921	81	23	the	the	DET
dpc-5921	81	24	face	face	NOUN
dpc-5921	81	25	or	or	CCONJ
dpc-5921	81	26	scalp	scalp	NOUN
dpc-5921	81	27	,	,	PUNCT
dpc-5921	81	28	has	have	AUX
dpc-5921	81	29	demonstrated	demonstrate	VERB
dpc-5921	81	30	significant	significant	ADJ
dpc-5921	81	31	clinical	clinical	ADJ
dpc-5921	81	32	potential	potential	NOUN
dpc-5921	81	33	owing	owe	VERB
dpc-5921	81	34	to	to	ADP
dpc-5921	81	35	its	its	PRON
dpc-5921	81	36	efficacy	efficacy	NOUN
dpc-5921	81	37	and	and	CCONJ
dpc-5921	81	38	good	good	ADJ
dpc-5921	81	39	tolerability	tolerability	NOUN
dpc-5921	81	40	,	,	PUNCT
dpc-5921	81	41	supported	support	VERB
dpc-5921	81	42	by	by	ADP
dpc-5921	81	43	a	a	DET
dpc-5921	81	44	novel	novel	ADJ
dpc-5921	81	45	mechanism	mechanism	NOUN
dpc-5921	81	46	of	of	ADP
dpc-5921	81	47	action	action	NOUN
dpc-5921	81	48	,	,	PUNCT
dpc-5921	81	49	as	as	ADV
dpc-5921	81	50	well	well	ADV
dpc-5921	81	51	as	as	ADP
dpc-5921	81	52	to	to	ADP
dpc-5921	81	53	its	its	PRON
dpc-5921	81	54	short	short	ADJ
dpc-5921	81	55	treatment	treatment	NOUN
dpc-5921	81	56	course	course	NOUN
dpc-5921	81	57	[	[	X
dpc-5921	81	58	1,3,6	1,3,6	NUM
dpc-5921	81	59	]	]	PUNCT
dpc-5921	81	60	.	.	PUNCT
dpc-5921	82	1	evidence	evidence	NOUN
dpc-5921	82	2	of	of	ADP
dpc-5921	82	3	tirbanibulin	tirbanibulin	PROPN
dpc-5921	82	4	efficacy	efficacy	NOUN
dpc-5921	82	5	and	and	CCONJ
dpc-5921	82	6	tolerability	tolerability	NOUN
dpc-5921	82	7	from	from	ADP
dpc-5921	82	8	clinical	clinical	ADJ
dpc-5921	82	9	studies	study	NOUN
dpc-5921	82	10	in	in	ADP
dpc-5921	82	11	the	the	DET
dpc-5921	82	12	phase	phase	NOUN
dpc-5921	82	13	iii	iii	NOUN
dpc-5921	82	14	registration	registration	NOUN
dpc-5921	82	15	trials	trial	NOUN
dpc-5921	82	16	(	(	PUNCT
dpc-5921	82	17	two	two	NUM
dpc-5921	82	18	identical	identical	ADJ
dpc-5921	82	19	multicenter	multicenter	NOUN
dpc-5921	82	20	randomized	randomize	VERB
dpc-5921	82	21	double	double	ADJ
dpc-5921	82	22	-	-	PUNCT
dpc-5921	82	23	blind	blind	ADJ
dpc-5921	82	24	placebo	placebo	NOUN
dpc-5921	82	25	-	-	PUNCT
dpc-5921	82	26	controlled	control	VERB
dpc-5921	82	27	clinical	clinical	ADJ
dpc-5921	82	28	studies	study	NOUN
dpc-5921	82	29	enrolling	enrol	VERB
dpc-5921	82	30	a	a	DET
dpc-5921	82	31	total	total	NOUN
dpc-5921	82	32	of	of	ADP
dpc-5921	82	33	702	702	NUM
dpc-5921	82	34	patients	patient	NOUN
dpc-5921	82	35	with	with	ADP
dpc-5921	82	36	ak	ak	PROPN
dpc-5921	82	37	on	on	ADP
dpc-5921	82	38	the	the	DET
dpc-5921	82	39	face	face	NOUN
dpc-5921	82	40	or	or	CCONJ
dpc-5921	82	41	scalp	scalp	NOUN
dpc-5921	82	42	)	)	PUNCT
dpc-5921	82	43	,	,	PUNCT
dpc-5921	82	44	the	the	DET
dpc-5921	82	45	percentage	percentage	NOUN
dpc-5921	82	46	of	of	ADP
dpc-5921	82	47	patients	patient	NOUN
dpc-5921	82	48	with	with	ADP
dpc-5921	82	49	complete	complete	ADJ
dpc-5921	82	50	clearance	clearance	NOUN
dpc-5921	82	51	(	(	PUNCT
dpc-5921	82	52	100	100	NUM
dpc-5921	82	53	%	%	NOUN
dpc-5921	82	54	reduction	reduction	NOUN
dpc-5921	82	55	in	in	ADP
dpc-5921	82	56	the	the	DET
dpc-5921	82	57	number	number	NOUN
dpc-5921	82	58	of	of	ADP
dpc-5921	82	59	lesions	lesion	NOUN
dpc-5921	82	60	,	,	PUNCT
dpc-5921	82	61	as	as	SCONJ
dpc-5921	82	62	assessed	assess	VERB
dpc-5921	82	63	at	at	ADP
dpc-5921	82	64	day	day	NOUN
dpc-5921	82	65	57	57	NUM
dpc-5921	82	66	after	after	ADP
dpc-5921	82	67	completion	completion	NOUN
dpc-5921	82	68	of	of	ADP
dpc-5921	82	69	a	a	DET
dpc-5921	82	70	5	5	NUM
dpc-5921	82	71	-	-	PUNCT
dpc-5921	82	72	day	day	NOUN
dpc-5921	82	73	regimen	regimen	NOUN
dpc-5921	82	74	)	)	PUNCT
dpc-5921	82	75	was	be	AUX
dpc-5921	82	76	significantly	significantly	ADV
dpc-5921	82	77	higher	high	ADJ
dpc-5921	82	78	for	for	ADP
dpc-5921	82	79	patients	patient	NOUN
dpc-5921	82	80	treated	treat	VERB
dpc-5921	82	81	with	with	ADP
dpc-5921	82	82	tirbanibulin	tirbanibulin	PROPN
dpc-5921	82	83	than	than	ADP
dpc-5921	82	84	for	for	ADP
dpc-5921	82	85	those	those	PRON
dpc-5921	82	86	who	who	PRON
dpc-5921	82	87	received	receive	VERB
dpc-5921	82	88	control	control	NOUN
dpc-5921	82	89	ointment	ointment	NOUN
dpc-5921	82	90	(	(	PUNCT
dpc-5921	82	91	44	44	NUM
dpc-5921	82	92	%	%	NOUN
dpc-5921	82	93	and	and	CCONJ
dpc-5921	82	94	54	54	NUM
dpc-5921	82	95	%	%	NOUN
dpc-5921	82	96	in	in	ADP
dpc-5921	82	97	trial	trial	NOUN
dpc-5921	82	98	1	1	NUM
dpc-5921	82	99	and	and	CCONJ
dpc-5921	82	100	2	2	NUM
dpc-5921	82	101	,	,	PUNCT
dpc-5921	82	102	respectively	respectively	ADV
dpc-5921	82	103	,	,	PUNCT
dpc-5921	82	104	vs	vs	ADP
dpc-5921	82	105	5	5	NUM
dpc-5921	82	106	%	%	NOUN
dpc-5921	82	107	and	and	CCONJ
dpc-5921	82	108	13	13	NUM
dpc-5921	82	109	%	%	NOUN
dpc-5921	82	110	,	,	PUNCT
dpc-5921	82	111	p<0.001	p<0.001	VERB
dpc-5921	82	112	for	for	ADP
dpc-5921	82	113	both	both	DET
dpc-5921	82	114	trails	trail	NOUN
dpc-5921	82	115	)	)	PUNCT
dpc-5921	82	116	,	,	PUNCT
dpc-5921	82	117	while	while	SCONJ
dpc-5921	82	118	the	the	DET
dpc-5921	82	119	percentages	percentage	NOUN
dpc-5921	82	120	of	of	ADP
dpc-5921	82	121	patients	patient	NOUN
dpc-5921	82	122	with	with	ADP
dpc-5921	82	123	partial	partial	ADJ
dpc-5921	82	124	clearance	clearance	NOUN
dpc-5921	82	125	(	(	PUNCT
dpc-5921	82	126	≥75	≥75	NOUN
dpc-5921	82	127	%	%	NOUN
dpc-5921	82	128	reduction	reduction	NOUN
dpc-5921	82	129	in	in	ADP
dpc-5921	82	130	the	the	DET
dpc-5921	82	131	number	number	NOUN
dpc-5921	82	132	of	of	ADP
dpc-5921	82	133	lesions	lesion	NOUN
dpc-5921	82	134	)	)	PUNCT
dpc-5921	82	135	were	be	AUX
dpc-5921	82	136	68	68	NUM
dpc-5921	82	137	%	%	NOUN
dpc-5921	82	138	and	and	CCONJ
dpc-5921	82	139	76	76	NUM
dpc-5921	82	140	%	%	NOUN
dpc-5921	82	141	vs	vs	ADP
dpc-5921	82	142	16	16	NUM
dpc-5921	82	143	%	%	NOUN
dpc-5921	82	144	and	and	CCONJ
dpc-5921	82	145	20	20	NUM
dpc-5921	82	146	%	%	NOUN
dpc-5921	82	147	,	,	PUNCT
dpc-5921	82	148	respectively	respectively	ADV
dpc-5921	82	149	;	;	PUNCT
dpc-5921	82	150	p<0.001	p<0.001	X
dpc-5921	82	151	)	)	PUNCT
dpc-5921	83	1	[	[	X
dpc-5921	83	2	8	8	NUM
dpc-5921	83	3	]	]	PUNCT
dpc-5921	83	4	.	.	PUNCT
dpc-5921	84	1	at	at	ADP
dpc-5921	84	2	1	1	NUM
dpc-5921	84	3	-	-	PUNCT
dpc-5921	84	4	year	year	NOUN
dpc-5921	84	5	follow	follow	NOUN
dpc-5921	84	6	-	-	PUNCT
dpc-5921	84	7	up	up	NOUN
dpc-5921	84	8	,	,	PUNCT
dpc-5921	84	9	the	the	DET
dpc-5921	84	10	estimated	estimate	VERB
dpc-5921	84	11	percentage	percentage	NOUN
dpc-5921	84	12	of	of	ADP
dpc-5921	84	13	tirbanibulin	tirbanibulin	PROPN
dpc-5921	84	14	recipients	recipient	NOUN
dpc-5921	84	15	with	with	ADP
dpc-5921	84	16	recurrent	recurrent	ADJ
dpc-5921	84	17	lesions	lesion	NOUN
dpc-5921	84	18	,	,	PUNCT
dpc-5921	84	19	among	among	ADP
dpc-5921	84	20	those	those	PRON
dpc-5921	84	21	who	who	PRON
dpc-5921	84	22	had	have	AUX
dpc-5921	84	23	experienced	experience	VERB
dpc-5921	84	24	complete	complete	ADJ
dpc-5921	84	25	clearance	clearance	NOUN
dpc-5921	84	26	,	,	PUNCT
dpc-5921	84	27	was	be	AUX
dpc-5921	84	28	47	47	NUM
dpc-5921	84	29	%	%	NOUN
dpc-5921	84	30	.	.	PUNCT
dpc-5921	85	1	tirbanibulin	tirbanibulin	PROPN
dpc-5921	85	2	was	be	AUX
dpc-5921	85	3	well	well	ADV
dpc-5921	85	4	tolerated	tolerate	VERB
dpc-5921	85	5	.	.	PUNCT
dpc-5921	86	1	local	local	ADJ
dpc-5921	86	2	reactions	reaction	NOUN
dpc-5921	86	3	,	,	PUNCT
dpc-5921	86	4	including	include	VERB
dpc-5921	86	5	erythema	erythema	ADV
dpc-5921	86	6	,	,	PUNCT
dpc-5921	86	7	flaking/	flaking/	NUM
dpc-5921	86	8	scaling	scaling	NOUN
dpc-5921	86	9	,	,	PUNCT
dpc-5921	86	10	pruritus	pruritus	NOUN
dpc-5921	86	11	,	,	PUNCT
dpc-5921	86	12	and	and	CCONJ
dpc-5921	86	13	pain	pain	NOUN
dpc-5921	86	14	at	at	ADP
dpc-5921	86	15	the	the	DET
dpc-5921	86	16	application	application	NOUN
dpc-5921	86	17	site	site	NOUN
dpc-5921	86	18	,	,	PUNCT
dpc-5921	86	19	were	be	AUX
dpc-5921	86	20	mostly	mostly	ADV
dpc-5921	86	21	graded	grade	VERB
dpc-5921	86	22	as	as	ADV
dpc-5921	86	23	mild	mild	ADJ
dpc-5921	86	24	or	or	CCONJ
dpc-5921	86	25	moderate	moderate	ADJ
dpc-5921	86	26	and	and	CCONJ
dpc-5921	86	27	resolved	resolve	VERB
dpc-5921	86	28	spontaneously	spontaneously	ADV
dpc-5921	86	29	.	.	PUNCT
dpc-5921	87	1	unlike	unlike	ADP
dpc-5921	87	2	with	with	ADP
dpc-5921	87	3	most	most	ADJ
dpc-5921	87	4	topical	topical	ADJ
dpc-5921	87	5	therapies	therapy	NOUN
dpc-5921	87	6	,	,	PUNCT
dpc-5921	87	7	severe	severe	ADJ
dpc-5921	87	8	local	local	ADJ
dpc-5921	87	9	reactions	reaction	NOUN
dpc-5921	87	10	(	(	PUNCT
dpc-5921	87	11	e.g.	e.g.	ADV
dpc-5921	87	12	,	,	PUNCT
dpc-5921	87	13	  	  	SPACE
dpc-5921	87	14	vesicles	vesicle	NOUN
dpc-5921	87	15	/pustules	/pustule	NOUN
dpc-5921	87	16	,	,	PUNCT
dpc-5921	87	17	erosion	erosion	NOUN
dpc-5921	87	18	/	/	SYM
dpc-5921	87	19	ulceration	ulceration	NOUN
dpc-5921	87	20	)	)	PUNCT
dpc-5921	87	21	were	be	AUX
dpc-5921	87	22	infrequent	infrequent	ADJ
dpc-5921	87	23	.	.	PUNCT
dpc-5921	88	1	as	as	SCONJ
dpc-5921	88	2	expected	expect	VERB
dpc-5921	88	3	from	from	ADP
dpc-5921	88	4	the	the	DET
dpc-5921	88	5	negligible	negligible	ADJ
dpc-5921	88	6	absorption	absorption	NOUN
dpc-5921	88	7	rate	rate	NOUN
dpc-5921	88	8	of	of	ADP
dpc-5921	88	9	tirbanibulin	tirbanibulin	PROPN
dpc-5921	88	10	,	,	PUNCT
dpc-5921	88	11	systemic	systemic	ADJ
dpc-5921	88	12	adverse	adverse	ADJ
dpc-5921	88	13	is	be	AUX
dpc-5921	88	14	still	still	ADV
dpc-5921	88	15	a	a	DET
dpc-5921	88	16	matter	matter	NOUN
dpc-5921	88	17	of	of	ADP
dpc-5921	88	18	debate	debate	NOUN
dpc-5921	88	19	.	.	PUNCT
dpc-5921	89	1	although	although	SCONJ
dpc-5921	89	2	prevention	prevention	NOUN
dpc-5921	89	3	of	of	ADP
dpc-5921	89	4	progression	progression	NOUN
dpc-5921	89	5	to	to	PART
dpc-5921	89	6	invasive	invasive	ADJ
dpc-5921	89	7	cscc	cscc	NOUN
dpc-5921	89	8	is	be	AUX
dpc-5921	89	9	still	still	ADV
dpc-5921	89	10	generally	generally	ADV
dpc-5921	89	11	considered	consider	VERB
dpc-5921	89	12	the	the	DET
dpc-5921	89	13	key	key	ADJ
dpc-5921	89	14	reason	reason	NOUN
dpc-5921	89	15	for	for	ADP
dpc-5921	89	16	treatment	treatment	NOUN
dpc-5921	89	17	,	,	PUNCT
dpc-5921	89	18	there	there	PRON
dpc-5921	89	19	is	be	VERB
dpc-5921	89	20	no	no	DET
dpc-5921	89	21	actual	actual	ADJ
dpc-5921	89	22	evidence	evidence	NOUN
dpc-5921	89	23	that	that	SCONJ
dpc-5921	89	24	treating	treat	VERB
dpc-5921	89	25	of	of	ADP
dpc-5921	89	26	ak	ak	PROPN
dpc-5921	89	27	and	and	CCONJ
dpc-5921	89	28	fc	fc	PROPN
dpc-5921	89	29	decreases	decrease	VERB
dpc-5921	89	30	the	the	DET
dpc-5921	89	31	risk	risk	NOUN
dpc-5921	89	32	of	of	ADP
dpc-5921	89	33	developing	develop	VERB
dpc-5921	89	34	cscc	cscc	NOUN
dpc-5921	89	35	in	in	ADP
dpc-5921	89	36	immunocompetent	immunocompetent	ADJ
dpc-5921	89	37	patients	patient	NOUN
dpc-5921	89	38	without	without	ADP
dpc-5921	89	39	a	a	DET
dpc-5921	89	40	previous	previous	ADJ
dpc-5921	89	41	skin	skin	NOUN
dpc-5921	89	42	cancer	cancer	NOUN
dpc-5921	89	43	history	history	NOUN
dpc-5921	89	44	[	[	X
dpc-5921	89	45	13,27	13,27	NUM
dpc-5921	89	46	]	]	PUNCT
dpc-5921	89	47	.	.	PUNCT
dpc-5921	90	1	few	few	ADJ
dpc-5921	90	2	studies	study	NOUN
dpc-5921	90	3	have	have	AUX
dpc-5921	90	4	specifically	specifically	ADV
dpc-5921	90	5	investigated	investigate	VERB
dpc-5921	90	6	the	the	DET
dpc-5921	90	7	incidence	incidence	NOUN
dpc-5921	90	8	of	of	ADP
dpc-5921	90	9	cscc	cscc	ADJ
dpc-5921	90	10	over	over	ADP
dpc-5921	90	11	time	time	NOUN
dpc-5921	90	12	in	in	ADP
dpc-5921	90	13	patients	patient	NOUN
dpc-5921	90	14	treated	treat	VERB
dpc-5921	90	15	for	for	ADP
dpc-5921	90	16	ak	ak	PROPN
dpc-5921	90	17	.	.	PROPN
dpc-5921	91	1	a	a	DET
dpc-5921	91	2	secondary	secondary	ADJ
dpc-5921	91	3	analysis	analysis	NOUN
dpc-5921	91	4	of	of	ADP
dpc-5921	91	5	a	a	DET
dpc-5921	91	6	randomized	randomized	ADJ
dpc-5921	91	7	clinical	clinical	ADJ
dpc-5921	91	8	trial	trial	NOUN
dpc-5921	91	9	found	find	VERB
dpc-5921	91	10	that	that	SCONJ
dpc-5921	91	11	the	the	DET
dpc-5921	91	12	4	4	NUM
dpc-5921	91	13	-	-	PUNCT
dpc-5921	91	14	year	year	NOUN
dpc-5921	91	15	risk	risk	NOUN
dpc-5921	91	16	of	of	ADP
dpc-5921	91	17	developing	develop	VERB
dpc-5921	91	18	cscc	cscc	NOUN
dpc-5921	91	19	in	in	ADP
dpc-5921	91	20	a	a	DET
dpc-5921	91	21	previously	previously	ADV
dpc-5921	91	22	treated	treat	VERB
dpc-5921	91	23	ak	ak	PROPN
dpc-5921	91	24	area	area	NOUN
dpc-5921	91	25	was	be	AUX
dpc-5921	91	26	3.7	3.7	NUM
dpc-5921	91	27	%	%	NOUN
dpc-5921	91	28	,	,	PUNCT
dpc-5921	91	29	increasing	increase	VERB
dpc-5921	91	30	to	to	ADP
dpc-5921	91	31	20.9	20.9	NUM
dpc-5921	91	32	%	%	NOUN
dpc-5921	91	33	in	in	ADP
dpc-5921	91	34	patients	patient	NOUN
dpc-5921	91	35	with	with	ADP
dpc-5921	91	36	olsen	olsen	NOUN
dpc-5921	91	37	grade	grade	PROPN
dpc-5921	91	38	iii	iii	NUM
dpc-5921	91	39	lesions	lesion	NOUN
dpc-5921	91	40	and	and	CCONJ
dpc-5921	91	41	to	to	ADP
dpc-5921	91	42	33.5	33.5	NUM
dpc-5921	91	43	%	%	NOUN
dpc-5921	91	44	in	in	ADP
dpc-5921	91	45	those	those	PRON
dpc-5921	91	46	with	with	ADP
dpc-5921	91	47	severe	severe	ADJ
dpc-5921	91	48	ak	ak	PROPN
dpc-5921	91	49	needing	need	VERB
dpc-5921	91	50	retreatment	retreatment	NOUN
dpc-5921	91	51	,	,	PUNCT
dpc-5921	91	52	while	while	SCONJ
dpc-5921	91	53	a	a	DET
dpc-5921	91	54	retrospective	retrospective	ADJ
dpc-5921	91	55	cohort	cohort	NOUN
dpc-5921	91	56	study	study	NOUN
dpc-5921	91	57	that	that	PRON
dpc-5921	91	58	followed	follow	VERB
dpc-5921	91	59	5700	5700	NUM
dpc-5921	91	60	patients	patient	NOUN
dpc-5921	91	61	for	for	ADP
dpc-5921	91	62	five	five	NUM
dpc-5921	91	63	years	year	NOUN
dpc-5921	91	64	after	after	ADP
dpc-5921	91	65	treatment	treatment	NOUN
dpc-5921	91	66	with	with	ADP
dpc-5921	91	67	5	5	NUM
dpc-5921	91	68	-	-	PUNCT
dpc-5921	91	69	fluorouracil	fluorouracil	NOUN
dpc-5921	91	70	or	or	CCONJ
dpc-5921	91	71	imiquimod	imiquimod	PROPN
dpc-5921	91	72	found	find	VERB
dpc-5921	91	73	no	no	DET
dpc-5921	91	74	significant	significant	ADJ
dpc-5921	91	75	difference	difference	NOUN
dpc-5921	91	76	between	between	ADP
dpc-5921	91	77	the	the	DET
dpc-5921	91	78	two	two	NUM
dpc-5921	91	79	treatments	treatment	NOUN
dpc-5921	91	80	in	in	ADP
dpc-5921	91	81	the	the	DET
dpc-5921	91	82	2or	2or	ADJ
dpc-5921	91	83	5	5	NUM
dpc-5921	91	84	-	-	PUNCT
dpc-5921	91	85	year	year	NOUN
dpc-5921	91	86	cumulative	cumulative	ADJ
dpc-5921	91	87	risk	risk	NOUN
dpc-5921	91	88	for	for	ADP
dpc-5921	91	89	a	a	DET
dpc-5921	91	90	subsequent	subsequent	ADJ
dpc-5921	91	91	keratinocyte	keratinocyte	NOUN
dpc-5921	91	92	carcinoma	carcinoma	NOUN
dpc-5921	92	1	[	[	X
dpc-5921	92	2	28,29	28,29	NUM
dpc-5921	92	3	]	]	X
dpc-5921	92	4	.	.	PUNCT
dpc-5921	93	1	however	however	ADV
dpc-5921	93	2	,	,	PUNCT
dpc-5921	93	3	since	since	SCONJ
dpc-5921	93	4	these	these	DET
dpc-5921	93	5	studies	study	NOUN
dpc-5921	93	6	did	do	AUX
dpc-5921	93	7	not	not	PART
dpc-5921	93	8	include	include	VERB
dpc-5921	93	9	a	a	DET
dpc-5921	93	10	control	control	NOUN
dpc-5921	93	11	arm	arm	NOUN
dpc-5921	93	12	of	of	ADP
dpc-5921	93	13	untreated	untreated	ADJ
dpc-5921	93	14	patients	patient	NOUN
dpc-5921	93	15	,	,	PUNCT
dpc-5921	93	16	the	the	DET
dpc-5921	93	17	impact	impact	NOUN
dpc-5921	93	18	of	of	ADP
dpc-5921	93	19	ak	ak	PROPN
dpc-5921	93	20	treatment	treatment	NOUN
dpc-5921	93	21	per	per	X
dpc-5921	93	22	se	se	X
dpc-5921	93	23	on	on	ADP
dpc-5921	93	24	the	the	DET
dpc-5921	93	25	risk	risk	NOUN
dpc-5921	93	26	of	of	ADP
dpc-5921	93	27	developing	develop	VERB
dpc-5921	93	28	cscc	cscc	ADJ
dpc-5921	93	29	remains	remain	VERB
dpc-5921	93	30	unclear	unclear	ADJ
dpc-5921	93	31	.	.	PUNCT
dpc-5921	94	1	aside	aside	ADV
dpc-5921	94	2	from	from	ADP
dpc-5921	94	3	the	the	DET
dpc-5921	94	4	potential	potential	ADJ
dpc-5921	94	5	reduction	reduction	NOUN
dpc-5921	94	6	in	in	ADP
dpc-5921	94	7	the	the	DET
dpc-5921	94	8	risk	risk	NOUN
dpc-5921	94	9	of	of	ADP
dpc-5921	94	10	progression	progression	NOUN
dpc-5921	94	11	,	,	PUNCT
dpc-5921	94	12	the	the	DET
dpc-5921	94	13	treatment	treatment	NOUN
dpc-5921	94	14	goals	goal	NOUN
dpc-5921	94	15	of	of	ADP
dpc-5921	94	16	ak	ak	PROPN
dpc-5921	94	17	therapy	therapy	NOUN
dpc-5921	94	18	are	be	AUX
dpc-5921	94	19	sustained	sustain	VERB
dpc-5921	94	20	total	total	ADJ
dpc-5921	94	21	or	or	CCONJ
dpc-5921	94	22	partial	partial	ADJ
dpc-5921	94	23	clearance	clearance	NOUN
dpc-5921	94	24	of	of	ADP
dpc-5921	94	25	visible	visible	ADJ
dpc-5921	94	26	lesions	lesion	NOUN
dpc-5921	94	27	and	and	CCONJ
dpc-5921	94	28	improvement	improvement	NOUN
dpc-5921	94	29	in	in	ADP
dpc-5921	94	30	fc	fc	PROPN
dpc-5921	94	31	.	.	PUNCT
dpc-5921	94	32	field	field	PROPN
dpc-5921	94	33	directed	direct	VERB
dpc-5921	94	34	therapies	therapy	NOUN
dpc-5921	94	35	are	be	AUX
dpc-5921	94	36	currently	currently	ADV
dpc-5921	94	37	the	the	DET
dpc-5921	94	38	preferred	preferred	ADJ
dpc-5921	94	39	option	option	NOUN
dpc-5921	94	40	for	for	ADP
dpc-5921	94	41	most	most	ADJ
dpc-5921	94	42	clinical	clinical	ADJ
dpc-5921	94	43	cases	case	NOUN
dpc-5921	94	44	of	of	ADP
dpc-5921	94	45	ak	ak	PROPN
dpc-5921	94	46	since	since	ADV
dpc-5921	94	47	,	,	PUNCT
dpc-5921	94	48	unlike	unlike	ADP
dpc-5921	94	49	lesion	lesion	NOUN
dpc-5921	94	50	-	-	PUNCT
dpc-5921	94	51	directed	direct	VERB
dpc-5921	94	52	treatments	treatment	NOUN
dpc-5921	94	53	,	,	PUNCT
dpc-5921	94	54	they	they	PRON
dpc-5921	94	55	can	can	AUX
dpc-5921	94	56	target	target	VERB
dpc-5921	94	57	the	the	DET
dpc-5921	94	58	subclinical	subclinical	ADJ
dpc-5921	94	59	changes	change	NOUN
dpc-5921	94	60	underlying	underlie	VERB
dpc-5921	94	61	fc	fc	PROPN
dpc-5921	94	62	.	.	PUNCT
dpc-5921	95	1	however	however	ADV
dpc-5921	95	2	,	,	PUNCT
dpc-5921	95	3	many	many	ADJ
dpc-5921	95	4	field	field	NOUN
dpc-5921	95	5	therapies	therapy	NOUN
dpc-5921	95	6	with	with	ADP
dpc-5921	95	7	proven	prove	VERB
dpc-5921	95	8	efficacy	efficacy	NOUN
dpc-5921	95	9	(	(	PUNCT
dpc-5921	95	10	e.g.	e.g.	ADV
dpc-5921	95	11	,	,	PUNCT
dpc-5921	95	12	photodynamic	photodynamic	ADJ
dpc-5921	95	13	therapy	therapy	NOUN
dpc-5921	95	14	or	or	CCONJ
dpc-5921	95	15	5	5	NUM
dpc-5921	95	16	-	-	PUNCT
dpc-5921	95	17	fluorouracil	fluorouracil	NOUN
dpc-5921	95	18	)	)	PUNCT
dpc-5921	95	19	are	be	AUX
dpc-5921	95	20	associated	associate	VERB
dpc-5921	95	21	with	with	ADP
dpc-5921	95	22	adverse	adverse	ADJ
dpc-5921	95	23	events	event	NOUN
dpc-5921	95	24	such	such	ADJ
dpc-5921	95	25	as	as	ADP
dpc-5921	95	26	intense	intense	ADJ
dpc-5921	95	27	local	local	ADJ
dpc-5921	95	28	reactions	reaction	NOUN
dpc-5921	95	29	or	or	CCONJ
dpc-5921	95	30	pain	pain	NOUN
dpc-5921	95	31	,	,	PUNCT
dpc-5921	95	32	which	which	PRON
dpc-5921	95	33	restrict	restrict	VERB
dpc-5921	95	34	their	their	PRON
dpc-5921	95	35	use	use	NOUN
dpc-5921	95	36	and	and	CCONJ
dpc-5921	95	37	impact	impact	NOUN
dpc-5921	95	38	adherence	adherence	NOUN
dpc-5921	95	39	[	[	X
dpc-5921	95	40	1,3	1,3	NUM
dpc-5921	95	41	-	-	SYM
dpc-5921	95	42	5	5	NUM
dpc-5921	95	43	]	]	PUNCT
dpc-5921	95	44	.	.	PUNCT
dpc-5921	96	1	tirbanibulin	tirbanibulin	PROPN
dpc-5921	96	2	,	,	PUNCT
dpc-5921	96	3	figure	figure	VERB
dpc-5921	96	4	1	1	NUM
dpc-5921	96	5	.	.	PUNCT
dpc-5921	97	1	reflectance	reflectance	NOUN
dpc-5921	97	2	confocal	confocal	ADJ
dpc-5921	97	3	microscopy	microscopy	NOUN
dpc-5921	97	4	image	image	NOUN
dpc-5921	97	5	of	of	ADP
dpc-5921	97	6	a	a	DET
dpc-5921	97	7	small	small	ADJ
dpc-5921	97	8	area	area	NOUN
dpc-5921	97	9	of	of	ADP
dpc-5921	97	10	field	field	NOUN
dpc-5921	97	11	cancerization	cancerization	NOUN
dpc-5921	97	12	on	on	ADP
dpc-5921	97	13	the	the	DET
dpc-5921	97	14	right	right	ADJ
dpc-5921	97	15	temporal	temporal	ADJ
dpc-5921	97	16	area	area	NOUN
dpc-5921	97	17	of	of	ADP
dpc-5921	97	18	a	a	DET
dpc-5921	97	19	63	63	NUM
dpc-5921	97	20	-	-	PUNCT
dpc-5921	97	21	year	year	NOUN
dpc-5921	97	22	-	-	PUNCT
dpc-5921	97	23	old	old	ADJ
dpc-5921	97	24	male	male	NOUN
dpc-5921	97	25	with	with	ADP
dpc-5921	97	26	multiple	multiple	ADJ
dpc-5921	97	27	ak	ak	PROPN
dpc-5921	97	28	lesions	lesion	NOUN
dpc-5921	97	29	on	on	ADP
dpc-5921	97	30	the	the	DET
dpc-5921	97	31	face	face	NOUN
dpc-5921	97	32	and	and	CCONJ
dpc-5921	97	33	scalp	scalp	NOUN
dpc-5921	97	34	and	and	CCONJ
dpc-5921	97	35	a	a	DET
dpc-5921	97	36	history	history	NOUN
dpc-5921	97	37	of	of	ADP
dpc-5921	97	38	chronic	chronic	ADJ
dpc-5921	97	39	myelofibrosis	myelofibrosis	NOUN
dpc-5921	97	40	and	and	CCONJ
dpc-5921	97	41	resected	resect	VERB
dpc-5921	97	42	melanomas	melanoma	NOUN
dpc-5921	97	43	:	:	PUNCT
dpc-5921	97	44	(	(	PUNCT
dpc-5921	97	45	a	a	X
dpc-5921	97	46	)	)	PUNCT
dpc-5921	97	47	before	before	ADP
dpc-5921	97	48	treatment	treatment	NOUN
dpc-5921	97	49	,	,	PUNCT
dpc-5921	97	50	showing	show	VERB
dpc-5921	97	51	atypical	atypical	ADJ
dpc-5921	97	52	honeycomb	honeycomb	NOUN
dpc-5921	97	53	pattern	pattern	NOUN
dpc-5921	97	54	together	together	ADV
dpc-5921	97	55	with	with	ADP
dpc-5921	97	56	small	small	ADJ
dpc-5921	97	57	bright	bright	ADJ
dpc-5921	97	58	round	round	ADJ
dpc-5921	97	59	inflammatory	inflammatory	ADJ
dpc-5921	97	60	cells	cell	NOUN
dpc-5921	97	61	;	;	PUNCT
dpc-5921	97	62	(	(	PUNCT
dpc-5921	97	63	b	b	X
dpc-5921	97	64	)	)	PUNCT
dpc-5921	97	65	at	at	ADP
dpc-5921	97	66	29	29	NUM
dpc-5921	97	67	days	day	NOUN
dpc-5921	97	68	after	after	ADP
dpc-5921	97	69	starting	start	VERB
dpc-5921	97	70	treatment	treatment	NOUN
dpc-5921	97	71	with	with	ADP
dpc-5921	97	72	tirbanibulin	tirbanibulin	PROPN
dpc-5921	97	73	1	1	NUM
dpc-5921	97	74	%	%	NOUN
dpc-5921	97	75	ointment	ointment	NOUN
dpc-5921	97	76	,	,	PUNCT
dpc-5921	97	77	showing	show	VERB
dpc-5921	97	78	partial	partial	ADJ
dpc-5921	97	79	restoration	restoration	NOUN
dpc-5921	97	80	of	of	ADP
dpc-5921	97	81	the	the	DET
dpc-5921	97	82	typical	typical	ADJ
dpc-5921	97	83	honeycomb	honeycomb	NOUN
dpc-5921	97	84	pattern	pattern	NOUN
dpc-5921	97	85	with	with	ADP
dpc-5921	97	86	no	no	DET
dpc-5921	97	87	atypical	atypical	ADJ
dpc-5921	97	88	features	feature	NOUN
dpc-5921	97	89	.	.	PUNCT
dpc-5921	98	1	(	(	PUNCT
dpc-5921	98	2	courtesy	courtesy	NOUN
dpc-5921	98	3	of	of	ADP
dpc-5921	98	4	dr	dr	PROPN
dpc-5921	98	5	.	.	PROPN
dpc-5921	98	6	f.	f.	PROPN
dpc-5921	98	7	venturi	venturi	PROPN
dpc-5921	98	8	)	)	PUNCT
dpc-5921	98	9	review	review	NOUN
dpc-5921	98	10	|	|	ADV
dpc-5921	98	11	dermatol	dermatol	ADJ
dpc-5921	98	12	pract	pract	NOUN
dpc-5921	98	13	concept	concept	NOUN
dpc-5921	98	14	.	.	PUNCT
dpc-5921	99	1	2025;15(3):5921	2025;15(3):5921	NUM
dpc-5921	99	2	5	5	NUM
dpc-5921	99	3	table	table	NOUN
dpc-5921	99	4	1	1	NUM
dpc-5921	99	5	.	.	PUNCT
dpc-5921	100	1	expert	expert	ADJ
dpc-5921	100	2	consensus	consensus	NOUN
dpc-5921	100	3	statements	statement	NOUN
dpc-5921	100	4	on	on	ADP
dpc-5921	100	5	optimal	optimal	ADJ
dpc-5921	100	6	use	use	NOUN
dpc-5921	100	7	of	of	ADP
dpc-5921	100	8	tirbanibulin	tirbanibulin	PROPN
dpc-5921	100	9	in	in	ADP
dpc-5921	100	10	the	the	DET
dpc-5921	100	11	treatment	treatment	NOUN
dpc-5921	100	12	of	of	ADP
dpc-5921	100	13	actinic	actinic	ADJ
dpc-5921	100	14	keratosis	keratosis	NOUN
dpc-5921	100	15	.	.	PUNCT
dpc-5921	101	1	a	a	X
dpc-5921	101	2	)	)	PUNCT
dpc-5921	101	3	clinical	clinical	ADJ
dpc-5921	101	4	assessment/	assessment/	NUM
dpc-5921	101	5	diagnostic	diagnostic	ADJ
dpc-5921	101	6	procedures	procedure	NOUN
dpc-5921	102	1	•	•	NOUN
dpc-5921	102	2	assessment	assessment	NOUN
dpc-5921	102	3	of	of	ADP
dpc-5921	102	4	patient	patient	ADJ
dpc-5921	102	5	characteristics	characteristic	NOUN
dpc-5921	102	6	(	(	PUNCT
dpc-5921	102	7	e.g.	e.g.	ADV
dpc-5921	102	8	,	,	PUNCT
dpc-5921	102	9	fitzpatrick	fitzpatrick	PROPN
dpc-5921	102	10	skin	skin	PROPN
dpc-5921	102	11	type	type	NOUN
dpc-5921	102	12	,	,	PUNCT
dpc-5921	102	13	comorbidities	comorbiditie	NOUN
dpc-5921	102	14	,	,	PUNCT
dpc-5921	102	15	previous	previous	ADJ
dpc-5921	102	16	therapies	therapy	NOUN
dpc-5921	102	17	,	,	PUNCT
dpc-5921	102	18	risk	risk	NOUN
dpc-5921	102	19	factors	factor	NOUN
dpc-5921	102	20	for	for	ADP
dpc-5921	102	21	ak	ak	NOUN
dpc-5921	102	22	,	,	PUNCT
dpc-5921	102	23	immunosuppression	immunosuppression	NOUN
dpc-5921	102	24	,	,	PUNCT
dpc-5921	102	25	history	history	NOUN
dpc-5921	102	26	of	of	ADP
dpc-5921	102	27	nmsc	nmsc	NOUN
dpc-5921	102	28	)	)	PUNCT
dpc-5921	102	29	should	should	AUX
dpc-5921	102	30	always	always	ADV
dpc-5921	102	31	be	be	AUX
dpc-5921	102	32	part	part	NOUN
dpc-5921	102	33	of	of	ADP
dpc-5921	102	34	the	the	DET
dpc-5921	102	35	clinical	clinical	ADJ
dpc-5921	102	36	examination	examination	NOUN
dpc-5921	102	37	•	•	SCONJ
dpc-5921	102	38	the	the	DET
dpc-5921	102	39	olsen	olsen	NOUN
dpc-5921	102	40	severity	severity	NOUN
dpc-5921	102	41	classification	classification	NOUN
dpc-5921	102	42	system	system	NOUN
dpc-5921	102	43	can	can	AUX
dpc-5921	102	44	be	be	AUX
dpc-5921	102	45	useful	useful	ADJ
dpc-5921	102	46	for	for	ADP
dpc-5921	102	47	evaluating	evaluate	VERB
dpc-5921	102	48	single	single	ADJ
dpc-5921	102	49	lesions	lesion	NOUN
dpc-5921	102	50	,	,	PUNCT
dpc-5921	102	51	but	but	CCONJ
dpc-5921	102	52	fc	fc	PROPN
dpc-5921	102	53	should	should	AUX
dpc-5921	102	54	also	also	ADV
dpc-5921	102	55	be	be	AUX
dpc-5921	102	56	assessed	assess	VERB
dpc-5921	102	57	,	,	PUNCT
dpc-5921	102	58	preferably	preferably	ADV
dpc-5921	102	59	by	by	ADP
dpc-5921	102	60	using	use	VERB
dpc-5921	102	61	the	the	DET
dpc-5921	102	62	actinic	actinic	ADJ
dpc-5921	102	63	keratosis	keratosis	NOUN
dpc-5921	102	64	field	field	NOUN
dpc-5921	102	65	assessment	assessment	NOUN
dpc-5921	102	66	scale	scale	NOUN
dpc-5921	102	67	(	(	PUNCT
dpc-5921	102	68	ak	ak	NOUN
dpc-5921	102	69	-	-	PUNCT
dpc-5921	102	70	fas	fas	NOUN
dpc-5921	102	71	)	)	PUNCT
dpc-5921	102	72	•	•	NOUN
dpc-5921	102	73	both	both	CCONJ
dpc-5921	102	74	ak	ak	PROPN
dpc-5921	102	75	lesions	lesion	NOUN
dpc-5921	102	76	and	and	CCONJ
dpc-5921	102	77	the	the	DET
dpc-5921	102	78	surrounding	surround	VERB
dpc-5921	102	79	skin	skin	NOUN
dpc-5921	102	80	should	should	AUX
dpc-5921	102	81	be	be	AUX
dpc-5921	102	82	carefully	carefully	ADV
dpc-5921	102	83	examined	examine	VERB
dpc-5921	102	84	•	•	NOUN
dpc-5921	102	85	the	the	DET
dpc-5921	102	86	use	use	NOUN
dpc-5921	102	87	of	of	ADP
dpc-5921	102	88	a	a	DET
dpc-5921	102	89	keratolytic	keratolytic	ADJ
dpc-5921	102	90	ointment	ointment	NOUN
dpc-5921	102	91	allows	allow	VERB
dpc-5921	102	92	a	a	DET
dpc-5921	102	93	better	well	ADJ
dpc-5921	102	94	evaluation	evaluation	NOUN
dpc-5921	102	95	of	of	ADP
dpc-5921	102	96	hyperkeratotic	hyperkeratotic	ADJ
dpc-5921	102	97	lesions	lesion	NOUN
dpc-5921	102	98	by	by	ADP
dpc-5921	102	99	reducing	reduce	VERB
dpc-5921	102	100	the	the	DET
dpc-5921	102	101	masking	masking	NOUN
dpc-5921	102	102	effect	effect	NOUN
dpc-5921	102	103	of	of	ADP
dpc-5921	102	104	the	the	DET
dpc-5921	102	105	scaly	scaly	NOUN
dpc-5921	102	106	tissue	tissue	NOUN
dpc-5921	102	107	•	•	NUM
dpc-5921	102	108	dermatoscopy	dermatoscopy	NOUN
dpc-5921	102	109	should	should	AUX
dpc-5921	102	110	always	always	ADV
dpc-5921	102	111	be	be	AUX
dpc-5921	102	112	carried	carry	VERB
dpc-5921	102	113	out	out	ADP
dpc-5921	102	114	,	,	PUNCT
dpc-5921	102	115	both	both	CCONJ
dpc-5921	102	116	at	at	ADP
dpc-5921	102	117	baseline	baseline	NOUN
dpc-5921	102	118	for	for	ADP
dpc-5921	102	119	diagnosis	diagnosis	NOUN
dpc-5921	102	120	and	and	CCONJ
dpc-5921	102	121	for	for	ADP
dpc-5921	102	122	monitoring	monitor	VERB
dpc-5921	102	123	treatment	treatment	NOUN
dpc-5921	102	124	response	response	NOUN
dpc-5921	102	125	•	•	ADP
dpc-5921	102	126	advanced	advanced	ADJ
dpc-5921	102	127	instrumental	instrumental	ADJ
dpc-5921	102	128	techniques	technique	NOUN
dpc-5921	102	129	(	(	PUNCT
dpc-5921	102	130	e.g.	e.g.	ADV
dpc-5921	102	131	rcm	rcm	PROPN
dpc-5921	102	132	,	,	PUNCT
dpc-5921	102	133	oct	oct	PROPN
dpc-5921	102	134	,	,	PUNCT
dpc-5921	102	135	lc	lc	PROPN
dpc-5921	102	136	-	-	PUNCT
dpc-5921	102	137	oct	oct	NOUN
dpc-5921	102	138	)	)	PUNCT
dpc-5921	102	139	or	or	CCONJ
dpc-5921	102	140	histopathological	histopathological	ADJ
dpc-5921	102	141	examination	examination	NOUN
dpc-5921	102	142	are	be	AUX
dpc-5921	102	143	not	not	PART
dpc-5921	102	144	routinely	routinely	ADV
dpc-5921	102	145	necessary	necessary	ADJ
dpc-5921	102	146	,	,	PUNCT
dpc-5921	102	147	but	but	CCONJ
dpc-5921	102	148	may	may	AUX
dpc-5921	102	149	be	be	AUX
dpc-5921	102	150	useful	useful	ADJ
dpc-5921	102	151	in	in	ADP
dpc-5921	102	152	specific	specific	ADJ
dpc-5921	102	153	cases	case	NOUN
dpc-5921	102	154	b	b	NOUN
dpc-5921	102	155	)	)	PUNCT
dpc-5921	102	156	treatment	treatment	NOUN
dpc-5921	102	157	•	•	NOUN
dpc-5921	102	158	due	due	ADP
dpc-5921	102	159	to	to	ADP
dpc-5921	102	160	the	the	DET
dpc-5921	102	161	chronic	chronic	ADJ
dpc-5921	102	162	nature	nature	NOUN
dpc-5921	102	163	of	of	ADP
dpc-5921	102	164	ak	ak	PROPN
dpc-5921	102	165	,	,	PUNCT
dpc-5921	102	166	repeated	repeat	VERB
dpc-5921	102	167	treatment	treatment	NOUN
dpc-5921	102	168	over	over	ADP
dpc-5921	102	169	time	time	NOUN
dpc-5921	102	170	is	be	AUX
dpc-5921	102	171	part	part	NOUN
dpc-5921	102	172	of	of	ADP
dpc-5921	102	173	the	the	DET
dpc-5921	102	174	long	long	ADJ
dpc-5921	102	175	-	-	PUNCT
dpc-5921	102	176	term	term	NOUN
dpc-5921	102	177	management	management	NOUN
dpc-5921	102	178	of	of	ADP
dpc-5921	102	179	ak	ak	PROPN
dpc-5921	102	180	•	•	NOUN
dpc-5921	102	181	compliance	compliance	NOUN
dpc-5921	102	182	is	be	AUX
dpc-5921	102	183	crucial	crucial	ADJ
dpc-5921	102	184	to	to	ADP
dpc-5921	102	185	treatment	treatment	NOUN
dpc-5921	102	186	success	success	NOUN
dpc-5921	102	187	•	•	ADP
dpc-5921	102	188	it	it	PRON
dpc-5921	102	189	is	be	AUX
dpc-5921	102	190	still	still	ADV
dpc-5921	102	191	a	a	DET
dpc-5921	102	192	matter	matter	NOUN
dpc-5921	102	193	of	of	ADP
dpc-5921	102	194	debate	debate	NOUN
dpc-5921	102	195	whether	whether	SCONJ
dpc-5921	102	196	treatment	treatment	NOUN
dpc-5921	102	197	of	of	ADP
dpc-5921	102	198	both	both	DET
dpc-5921	102	199	ak	ak	PROPN
dpc-5921	102	200	lesions	lesion	NOUN
dpc-5921	102	201	and	and	CCONJ
dpc-5921	102	202	fc	fc	PROPN
dpc-5921	102	203	can	can	AUX
dpc-5921	102	204	prevent	prevent	VERB
dpc-5921	102	205	progression	progression	NOUN
dpc-5921	102	206	to	to	ADP
dpc-5921	102	207	scc	scc	PROPN
dpc-5921	102	208	•	•	ADP
dpc-5921	102	209	tirbanibulin	tirbanibulin	PROPN
dpc-5921	102	210	can	can	AUX
dpc-5921	102	211	be	be	AUX
dpc-5921	102	212	considered	consider	VERB
dpc-5921	102	213	as	as	ADP
dpc-5921	102	214	a	a	DET
dpc-5921	102	215	first	first	ADJ
dpc-5921	102	216	-	-	PUNCT
dpc-5921	102	217	line	line	NOUN
dpc-5921	102	218	treatment	treatment	NOUN
dpc-5921	102	219	for	for	ADP
dpc-5921	102	220	most	most	ADJ
dpc-5921	102	221	patients	patient	NOUN
dpc-5921	102	222	(	(	PUNCT
dpc-5921	102	223	both	both	CCONJ
dpc-5921	102	224	treatmentnaïve	treatmentnaïve	NOUN
dpc-5921	102	225	and	and	CCONJ
dpc-5921	102	226	previously	previously	ADV
dpc-5921	102	227	treated	treat	VERB
dpc-5921	102	228	)	)	PUNCT
dpc-5921	102	229	because	because	SCONJ
dpc-5921	102	230	of	of	ADP
dpc-5921	102	231	its	its	PRON
dpc-5921	102	232	efficacy	efficacy	NOUN
dpc-5921	102	233	,	,	PUNCT
dpc-5921	102	234	short	short	ADJ
dpc-5921	102	235	regimen	regiman	NOUN
dpc-5921	102	236	,	,	PUNCT
dpc-5921	102	237	and	and	CCONJ
dpc-5921	102	238	favorable	favorable	ADJ
dpc-5921	102	239	tolerability	tolerability	NOUN
dpc-5921	102	240	profile	profile	NOUN
dpc-5921	102	241	•	•	ADP
dpc-5921	102	242	the	the	DET
dpc-5921	102	243	area	area	NOUN
dpc-5921	102	244	of	of	ADP
dpc-5921	102	245	skin	skin	NOUN
dpc-5921	102	246	to	to	PART
dpc-5921	102	247	be	be	AUX
dpc-5921	102	248	covered	cover	VERB
dpc-5921	102	249	by	by	ADP
dpc-5921	102	250	tirbanibulin	tirbanibulin	DET
dpc-5921	102	251	1	1	NUM
dpc-5921	102	252	%	%	NOUN
dpc-5921	102	253	ointment	ointment	NOUN
dpc-5921	102	254	depends	depend	VERB
dpc-5921	102	255	on	on	ADP
dpc-5921	102	256	the	the	DET
dpc-5921	102	257	distribution	distribution	NOUN
dpc-5921	102	258	of	of	ADP
dpc-5921	102	259	ak	ak	PROPN
dpc-5921	102	260	lesions	lesion	NOUN
dpc-5921	102	261	and	and	CCONJ
dpc-5921	102	262	fc	fc	X
dpc-5921	102	263	•	•	NUM
dpc-5921	102	264	the	the	DET
dpc-5921	102	265	area	area	NOUN
dpc-5921	102	266	of	of	ADP
dpc-5921	102	267	application	application	NOUN
dpc-5921	102	268	of	of	ADP
dpc-5921	102	269	tirbanibulin	tirbanibulin	PROPN
dpc-5921	102	270	is	be	AUX
dpc-5921	102	271	limited	limit	VERB
dpc-5921	102	272	to	to	ADP
dpc-5921	102	273	25	25	NUM
dpc-5921	102	274	cm2	cm2	NOUN
dpc-5921	102	275	for	for	ADP
dpc-5921	102	276	each	each	DET
dpc-5921	102	277	anatomical	anatomical	ADJ
dpc-5921	102	278	area	area	NOUN
dpc-5921	102	279	(	(	PUNCT
dpc-5921	102	280	scalp	scalp	NOUN
dpc-5921	102	281	,	,	PUNCT
dpc-5921	102	282	forehead	forehead	NOUN
dpc-5921	102	283	,	,	PUNCT
dpc-5921	102	284	left	leave	VERB
dpc-5921	102	285	/	/	SYM
dpc-5921	102	286	right	right	ADJ
dpc-5921	102	287	cheek	cheek	NOUN
dpc-5921	102	288	with	with	ADP
dpc-5921	102	289	ear	ear	NOUN
dpc-5921	102	290	,	,	PUNCT
dpc-5921	102	291	nose	nose	NOUN
dpc-5921	102	292	,	,	PUNCT
dpc-5921	102	293	and	and	CCONJ
dpc-5921	102	294	chin	chin	NOUN
dpc-5921	102	295	)	)	PUNCT
dpc-5921	102	296	•	•	ADV
dpc-5921	102	297	more	more	ADJ
dpc-5921	102	298	than	than	ADP
dpc-5921	102	299	25	25	NUM
dpc-5921	102	300	cm2	cm2	NOUN
dpc-5921	102	301	can	can	AUX
dpc-5921	102	302	be	be	AUX
dpc-5921	102	303	treated	treat	VERB
dpc-5921	102	304	by	by	ADP
dpc-5921	102	305	one	one	NUM
dpc-5921	102	306	sachet	sachet	NOUN
dpc-5921	102	307	of	of	ADP
dpc-5921	102	308	tirbanibulin	tirbanibulin	PROPN
dpc-5921	102	309	1	1	NUM
dpc-5921	102	310	%	%	NOUN
dpc-5921	102	311	ointment	ointment	NOUN
dpc-5921	102	312	•	•	NOUN
dpc-5921	102	313	when	when	SCONJ
dpc-5921	102	314	treating	treat	VERB
dpc-5921	102	315	large	large	ADJ
dpc-5921	102	316	fields	field	NOUN
dpc-5921	102	317	(	(	PUNCT
dpc-5921	102	318	>	>	X
dpc-5921	102	319	25	25	NUM
dpc-5921	102	320	cm2	cm2	NOUN
dpc-5921	102	321	)	)	PUNCT
dpc-5921	102	322	,	,	PUNCT
dpc-5921	102	323	sequential	sequential	ADJ
dpc-5921	102	324	or	or	CCONJ
dpc-5921	102	325	simultaneous	simultaneous	ADJ
dpc-5921	102	326	schedules	schedule	NOUN
dpc-5921	102	327	can	can	AUX
dpc-5921	102	328	be	be	AUX
dpc-5921	102	329	considered	consider	VERB
dpc-5921	102	330	•	•	SCONJ
dpc-5921	102	331	the	the	DET
dpc-5921	102	332	standard	standard	ADJ
dpc-5921	102	333	tirbanibulin	tirbanibulin	PROPN
dpc-5921	102	334	treatment	treatment	NOUN
dpc-5921	102	335	period	period	NOUN
dpc-5921	102	336	is	be	AUX
dpc-5921	102	337	five	five	NUM
dpc-5921	102	338	days	day	NOUN
dpc-5921	102	339	.	.	PUNCT
dpc-5921	103	1	up	up	ADP
dpc-5921	103	2	to	to	PART
dpc-5921	103	3	four	four	NUM
dpc-5921	103	4	consecutive	consecutive	ADJ
dpc-5921	103	5	treatment	treatment	NOUN
dpc-5921	103	6	cycles	cycle	NOUN
dpc-5921	103	7	1–2	1–2	NUM
dpc-5921	103	8	months	month	NOUN
dpc-5921	103	9	apart	apart	ADV
dpc-5921	103	10	can	can	AUX
dpc-5921	103	11	be	be	AUX
dpc-5921	103	12	planned	plan	VERB
dpc-5921	103	13	if	if	SCONJ
dpc-5921	103	14	needed	need	VERB
dpc-5921	103	15	•	•	NOUN
dpc-5921	103	16	multiple	multiple	ADJ
dpc-5921	103	17	treatment	treatment	NOUN
dpc-5921	103	18	cycles	cycle	NOUN
dpc-5921	103	19	can	can	AUX
dpc-5921	103	20	be	be	AUX
dpc-5921	103	21	performed	perform	VERB
dpc-5921	103	22	in	in	ADP
dpc-5921	103	23	immunocompromised	immunocompromise	VERB
dpc-5921	103	24	patients	patient	NOUN
dpc-5921	103	25	,	,	PUNCT
dpc-5921	103	26	those	those	PRON
dpc-5921	103	27	with	with	ADP
dpc-5921	103	28	a	a	DET
dpc-5921	103	29	history	history	NOUN
dpc-5921	103	30	of	of	ADP
dpc-5921	103	31	skin	skin	NOUN
dpc-5921	103	32	cancer	cancer	NOUN
dpc-5921	103	33	,	,	PUNCT
dpc-5921	103	34	or	or	CCONJ
dpc-5921	103	35	advanced	advanced	ADJ
dpc-5921	103	36	photodamage	photodamage	NOUN
dpc-5921	103	37	•	•	NUM
dpc-5921	103	38	patients	patient	NOUN
dpc-5921	103	39	should	should	AUX
dpc-5921	103	40	be	be	AUX
dpc-5921	103	41	informed	inform	VERB
dpc-5921	103	42	about	about	ADP
dpc-5921	103	43	the	the	DET
dpc-5921	103	44	chronic	chronic	ADJ
dpc-5921	103	45	nature	nature	NOUN
dpc-5921	103	46	of	of	ADP
dpc-5921	103	47	ak	ak	PROPN
dpc-5921	103	48	and	and	CCONJ
dpc-5921	103	49	the	the	DET
dpc-5921	103	50	need	need	NOUN
dpc-5921	103	51	for	for	ADP
dpc-5921	103	52	repeated	repeat	VERB
dpc-5921	103	53	treatments	treatment	NOUN
dpc-5921	103	54	over	over	ADP
dpc-5921	103	55	time	time	NOUN
dpc-5921	103	56	•	•	ADP
dpc-5921	103	57	although	although	SCONJ
dpc-5921	103	58	tirbanibulin	tirbanibulin	ADV
dpc-5921	103	59	-	-	PUNCT
dpc-5921	103	60	related	relate	VERB
dpc-5921	103	61	local	local	ADJ
dpc-5921	103	62	reactions	reaction	NOUN
dpc-5921	103	63	are	be	AUX
dpc-5921	103	64	usually	usually	ADV
dpc-5921	103	65	mild	mild	ADJ
dpc-5921	103	66	and	and	CCONJ
dpc-5921	103	67	transient	transient	ADJ
dpc-5921	103	68	,	,	PUNCT
dpc-5921	103	69	severe	severe	ADJ
dpc-5921	103	70	reactions	reaction	NOUN
dpc-5921	103	71	may	may	AUX
dpc-5921	103	72	occur	occur	VERB
dpc-5921	103	73	,	,	PUNCT
dpc-5921	103	74	and	and	CCONJ
dpc-5921	103	75	patients	patient	NOUN
dpc-5921	103	76	should	should	AUX
dpc-5921	103	77	be	be	AUX
dpc-5921	103	78	reassured	reassure	VERB
dpc-5921	103	79	•	•	ADP
dpc-5921	103	80	patients	patient	NOUN
dpc-5921	103	81	should	should	AUX
dpc-5921	103	82	be	be	AUX
dpc-5921	103	83	given	give	VERB
dpc-5921	103	84	detailed	detailed	ADJ
dpc-5921	103	85	instructions	instruction	NOUN
dpc-5921	103	86	about	about	ADP
dpc-5921	103	87	tirbanibulin	tirbanibulin	PROPN
dpc-5921	103	88	application	application	NOUN
dpc-5921	103	89	at	at	ADP
dpc-5921	103	90	home	home	PROPN
dpc-5921	103	91	ak	ak	PROPN
dpc-5921	103	92	:	:	PUNCT
dpc-5921	103	93	actinic	actinic	ADJ
dpc-5921	103	94	keratosis	keratosis	NOUN
dpc-5921	103	95	;	;	PUNCT
dpc-5921	103	96	fc	fc	X
dpc-5921	103	97	:	:	PUNCT
dpc-5921	103	98	field	field	NOUN
dpc-5921	103	99	cancerization	cancerization	NOUN
dpc-5921	103	100	;	;	PUNCT
dpc-5921	103	101	lc	lc	PROPN
dpc-5921	103	102	-	-	PUNCT
dpc-5921	103	103	oct	oct	NOUN
dpc-5921	103	104	:	:	PUNCT
dpc-5921	103	105	line	line	NOUN
dpc-5921	103	106	-	-	PUNCT
dpc-5921	103	107	field	field	NOUN
dpc-5921	103	108	confocal	confocal	ADJ
dpc-5921	103	109	optical	optical	ADJ
dpc-5921	103	110	coherence	coherence	NOUN
dpc-5921	103	111	tomography	tomography	NOUN
dpc-5921	103	112	;	;	PUNCT
dpc-5921	103	113	nmsc	nmsc	NOUN
dpc-5921	103	114	:	:	PUNCT
dpc-5921	103	115	non	non	ADJ
dpc-5921	103	116	-	-	ADJ
dpc-5921	103	117	melanoma	melanoma	ADJ
dpc-5921	103	118	skin	skin	NOUN
dpc-5921	103	119	cancer	cancer	NOUN
dpc-5921	103	120	;	;	PUNCT
dpc-5921	103	121	oct	oct	NOUN
dpc-5921	103	122	:	:	PUNCT
dpc-5921	103	123	optical	optical	ADJ
dpc-5921	103	124	coherence	coherence	NOUN
dpc-5921	103	125	tomography	tomography	NOUN
dpc-5921	103	126	;	;	PUNCT
dpc-5921	103	127	rcm	rcm	PROPN
dpc-5921	103	128	:	:	PUNCT
dpc-5921	103	129	reflectance	reflectance	NOUN
dpc-5921	103	130	confocal	confocal	ADJ
dpc-5921	103	131	microscopy	microscopy	NOUN
dpc-5921	103	132	;	;	PUNCT
dpc-5921	103	133	scc	scc	NOUN
dpc-5921	103	134	:	:	PUNCT
dpc-5921	103	135	squamous	squamous	ADJ
dpc-5921	103	136	cell	cell	NOUN
dpc-5921	103	137	carcinoma	carcinoma	NOUN
dpc-5921	103	138	.	.	PUNCT
dpc-5921	104	1	events	event	NOUN
dpc-5921	104	2	were	be	AUX
dpc-5921	104	3	uncommon	uncommon	ADJ
dpc-5921	104	4	.	.	PUNCT
dpc-5921	105	1	notably	notably	ADV
dpc-5921	105	2	,	,	PUNCT
dpc-5921	105	3	none	none	NOUN
dpc-5921	105	4	of	of	ADP
dpc-5921	105	5	the	the	DET
dpc-5921	105	6	patients	patient	NOUN
dpc-5921	105	7	discontinued	discontinue	VERB
dpc-5921	105	8	treatment	treatment	NOUN
dpc-5921	105	9	for	for	ADP
dpc-5921	105	10	tirbanibulin	tirbanibulin	ADV
dpc-5921	105	11	-	-	PUNCT
dpc-5921	105	12	related	relate	VERB
dpc-5921	105	13	adverse	adverse	ADJ
dpc-5921	105	14	events	event	NOUN
dpc-5921	105	15	[	[	X
dpc-5921	105	16	8	8	NUM
dpc-5921	105	17	]	]	PUNCT
dpc-5921	105	18	.	.	PUNCT
dpc-5921	106	1	post	post	ADJ
dpc-5921	106	2	-	-	ADJ
dpc-5921	106	3	hoc	hoc	ADJ
dpc-5921	106	4	analyses	analysis	NOUN
dpc-5921	106	5	of	of	ADP
dpc-5921	106	6	these	these	DET
dpc-5921	106	7	phase	phase	NOUN
dpc-5921	106	8	3	3	NUM
dpc-5921	106	9	trials	trial	NOUN
dpc-5921	106	10	suggested	suggest	VERB
dpc-5921	106	11	that	that	SCONJ
dpc-5921	106	12	comorbidities	comorbiditie	NOUN
dpc-5921	106	13	and	and	CCONJ
dpc-5921	106	14	concomitant	concomitant	ADJ
dpc-5921	106	15	treatments	treatment	NOUN
dpc-5921	106	16	(	(	PUNCT
dpc-5921	106	17	which	which	PRON
dpc-5921	106	18	were	be	AUX
dpc-5921	106	19	common	common	ADJ
dpc-5921	106	20	in	in	ADP
dpc-5921	106	21	the	the	DET
dpc-5921	106	22	elderly	elderly	ADJ
dpc-5921	106	23	population	population	NOUN
dpc-5921	106	24	enrolled	enrol	VERB
dpc-5921	106	25	in	in	ADP
dpc-5921	106	26	the	the	DET
dpc-5921	106	27	studies	study	NOUN
dpc-5921	106	28	)	)	PUNCT
dpc-5921	106	29	do	do	AUX
dpc-5921	106	30	not	not	PART
dpc-5921	106	31	affect	affect	VERB
dpc-5921	106	32	the	the	DET
dpc-5921	106	33	efficacy	efficacy	NOUN
dpc-5921	106	34	and	and	CCONJ
dpc-5921	106	35	tolerability	tolerability	NOUN
dpc-5921	106	36	of	of	ADP
dpc-5921	106	37	tirbanibulin	tirbanibulin	PROPN
dpc-5921	106	38	.	.	PUNCT
dpc-5921	107	1	also	also	ADV
dpc-5921	107	2	,	,	PUNCT
dpc-5921	107	3	no	no	DET
dpc-5921	107	4	correlation	correlation	NOUN
dpc-5921	107	5	was	be	AUX
dpc-5921	107	6	found	find	VERB
dpc-5921	107	7	between	between	ADP
dpc-5921	107	8	the	the	DET
dpc-5921	107	9	number	number	NOUN
dpc-5921	107	10	of	of	ADP
dpc-5921	107	11	ak	ak	PROPN
dpc-5921	107	12	lesions	lesion	NOUN
dpc-5921	107	13	at	at	ADP
dpc-5921	107	14	baseline	baseline	NOUN
dpc-5921	107	15	and	and	CCONJ
dpc-5921	107	16	the	the	DET
dpc-5921	107	17	severity	severity	NOUN
dpc-5921	107	18	of	of	ADP
dpc-5921	107	19	local	local	ADJ
dpc-5921	107	20	reactions	reaction	NOUN
dpc-5921	107	21	in	in	ADP
dpc-5921	107	22	tirbanibulin	tirbanibulin	ADV
dpc-5921	107	23	-	-	PUNCT
dpc-5921	107	24	treated	treat	VERB
dpc-5921	107	25	patients	patient	NOUN
dpc-5921	107	26	[	[	X
dpc-5921	107	27	30	30	NUM
dpc-5921	107	28	]	]	PUNCT
dpc-5921	107	29	.	.	PUNCT
dpc-5921	108	1	the	the	DET
dpc-5921	108	2	efficacy	efficacy	NOUN
dpc-5921	108	3	and	and	CCONJ
dpc-5921	108	4	favorable	favorable	ADJ
dpc-5921	108	5	tolerability	tolerability	NOUN
dpc-5921	108	6	profile	profile	NOUN
dpc-5921	108	7	of	of	ADP
dpc-5921	108	8	tirbanibulin	tirbanibulin	PROPN
dpc-5921	108	9	as	as	ADV
dpc-5921	108	10	well	well	ADV
dpc-5921	108	11	as	as	ADP
dpc-5921	108	12	the	the	DET
dpc-5921	108	13	high	high	ADJ
dpc-5921	108	14	rates	rate	NOUN
dpc-5921	108	15	of	of	ADP
dpc-5921	108	16	treatment	treatment	NOUN
dpc-5921	108	17	compliance	compliance	NOUN
dpc-5921	108	18	have	have	AUX
dpc-5921	108	19	been	be	AUX
dpc-5921	108	20	confirmed	confirm	VERB
dpc-5921	108	21	in	in	ADP
dpc-5921	108	22	several	several	ADJ
dpc-5921	108	23	real	real	ADJ
dpc-5921	108	24	-	-	PUNCT
dpc-5921	108	25	life	life	NOUN
dpc-5921	108	26	studies	study	NOUN
dpc-5921	108	27	,	,	PUNCT
dpc-5921	108	28	including	include	VERB
dpc-5921	108	29	case	case	NOUN
dpc-5921	108	30	series	series	NOUN
dpc-5921	108	31	and	and	CCONJ
dpc-5921	108	32	prospective	prospective	ADJ
dpc-5921	108	33	or	or	CCONJ
dpc-5921	108	34	retrospective	retrospective	ADJ
dpc-5921	108	35	observational	observational	ADJ
dpc-5921	108	36	studies	study	NOUN
dpc-5921	108	37	[	[	X
dpc-5921	108	38	9	9	NUM
dpc-5921	108	39	-	-	SYM
dpc-5921	108	40	11,30,31	11,30,31	NUM
dpc-5921	108	41	]	]	PUNCT
dpc-5921	108	42	.	.	PUNCT
dpc-5921	109	1	despite	despite	SCONJ
dpc-5921	109	2	their	their	PRON
dpc-5921	109	3	limitations	limitation	NOUN
dpc-5921	109	4	(	(	PUNCT
dpc-5921	109	5	e.g.	e.g.	ADV
dpc-5921	109	6	,	,	PUNCT
dpc-5921	109	7	lack	lack	NOUN
dpc-5921	109	8	of	of	ADP
dpc-5921	109	9	a	a	DET
dpc-5921	109	10	control	control	NOUN
dpc-5921	109	11	group	group	NOUN
dpc-5921	109	12	,	,	PUNCT
dpc-5921	109	13	small	small	ADJ
dpc-5921	109	14	number	number	NOUN
dpc-5921	109	15	of	of	ADP
dpc-5921	109	16	cases	case	NOUN
dpc-5921	109	17	in	in	ADP
dpc-5921	109	18	some	some	DET
dpc-5921	109	19	reports	report	NOUN
dpc-5921	109	20	)	)	PUNCT
dpc-5921	109	21	,	,	PUNCT
dpc-5921	109	22	the	the	DET
dpc-5921	109	23	findings	finding	NOUN
dpc-5921	109	24	of	of	ADP
dpc-5921	109	25	real	real	ADJ
dpc-5921	109	26	-	-	PUNCT
dpc-5921	109	27	life	life	NOUN
dpc-5921	109	28	studies	study	NOUN
dpc-5921	109	29	offer	offer	VERB
dpc-5921	109	30	an	an	DET
dpc-5921	109	31	insight	insight	NOUN
dpc-5921	109	32	into	into	ADP
dpc-5921	109	33	the	the	DET
dpc-5921	109	34	effects	effect	NOUN
dpc-5921	109	35	of	of	ADP
dpc-5921	109	36	tirbanibulin	tirbanibulin	PROPN
dpc-5921	109	37	in	in	ADP
dpc-5921	109	38	a	a	DET
dpc-5921	109	39	much	much	ADV
dpc-5921	109	40	wider	wide	ADJ
dpc-5921	109	41	spectrum	spectrum	NOUN
dpc-5921	109	42	of	of	ADP
dpc-5921	109	43	patients	patient	NOUN
dpc-5921	109	44	and	and	CCONJ
dpc-5921	109	45	clinical	clinical	ADJ
dpc-5921	109	46	presentations	presentation	NOUN
dpc-5921	109	47	compared	compare	VERB
dpc-5921	109	48	with	with	ADP
dpc-5921	109	49	the	the	DET
dpc-5921	109	50	populations	population	NOUN
dpc-5921	109	51	enrolled	enrol	VERB
dpc-5921	109	52	in	in	ADP
dpc-5921	109	53	randomized	randomized	ADJ
dpc-5921	109	54	clinical	clinical	ADJ
dpc-5921	109	55	trials	trial	NOUN
dpc-5921	109	56	.	.	PUNCT
dpc-5921	110	1	although	although	SCONJ
dpc-5921	110	2	the	the	DET
dpc-5921	110	3	european	european	ADJ
dpc-5921	110	4	indication	indication	NOUN
dpc-5921	110	5	of	of	ADP
dpc-5921	110	6	tirbanibulin	tirbanibulin	PROPN
dpc-5921	110	7	is	be	AUX
dpc-5921	110	8	for	for	ADP
dpc-5921	110	9	treatment	treatment	NOUN
dpc-5921	110	10	of	of	ADP
dpc-5921	110	11	non	non	ADJ
dpc-5921	110	12	-	-	ADJ
dpc-5921	110	13	hyperkeratotic	hyperkeratotic	ADJ
dpc-5921	110	14	,	,	PUNCT
dpc-5921	110	15	non	non	ADJ
dpc-5921	110	16	-	-	ADJ
dpc-5921	110	17	hypertrophic	hypertrophic	ADJ
dpc-5921	110	18	ak	ak	PROPN
dpc-5921	110	19	(	(	PUNCT
dpc-5921	110	20	olsen	olsen	NOUN
dpc-5921	110	21	grade	grade	PROPN
dpc-5921	110	22	i	i	PROPN
dpc-5921	110	23	)	)	PUNCT
dpc-5921	110	24	of	of	ADP
dpc-5921	110	25	the	the	DET
dpc-5921	110	26	face	face	NOUN
dpc-5921	110	27	or	or	CCONJ
dpc-5921	110	28	scalp	scalp	NOUN
dpc-5921	110	29	,	,	PUNCT
dpc-5921	110	30	its	its	PRON
dpc-5921	110	31	use	use	NOUN
dpc-5921	110	32	has	have	AUX
dpc-5921	110	33	been	be	AUX
dpc-5921	110	34	successfully	successfully	ADV
dpc-5921	110	35	extended	extend	VERB
dpc-5921	110	36	to	to	ADP
dpc-5921	110	37	a	a	DET
dpc-5921	110	38	range	range	NOUN
dpc-5921	110	39	of	of	ADP
dpc-5921	110	40	clinical	clinical	ADJ
dpc-5921	110	41	conditions	condition	NOUN
dpc-5921	110	42	,	,	PUNCT
dpc-5921	110	43	including	include	VERB
dpc-5921	110	44	ak	ak	PROPN
dpc-5921	110	45	patients	patient	NOUN
dpc-5921	110	46	with	with	ADP
dpc-5921	110	47	olsen	olsen	PROPN
dpc-5921	110	48	grade	grade	PROPN
dpc-5921	110	49	ii	ii	PROPN
dpc-5921	110	50	or	or	CCONJ
dpc-5921	110	51	iii	iii	NUM
dpc-5921	110	52	lesions	lesion	NOUN
dpc-5921	110	53	,	,	PUNCT
dpc-5921	110	54	ak	ak	PROPN
dpc-5921	110	55	lesions	lesion	NOUN
dpc-5921	110	56	located	locate	VERB
dpc-5921	110	57	on	on	ADP
dpc-5921	110	58	the	the	DET
dpc-5921	110	59	trunk	trunk	NOUN
dpc-5921	110	60	or	or	CCONJ
dpc-5921	110	61	limbs	limb	NOUN
dpc-5921	110	62	,	,	PUNCT
dpc-5921	110	63	or	or	CCONJ
dpc-5921	110	64	ak	ak	PROPN
dpc-5921	110	65	in	in	ADP
dpc-5921	110	66	organ	organ	NOUN
dpc-5921	110	67	transplant	transplant	NOUN
dpc-5921	110	68	recipients	recipient	NOUN
dpc-5921	110	69	[	[	X
dpc-5921	110	70	9,30,31	9,30,31	NUM
dpc-5921	110	71	]	]	X
dpc-5921	110	72	.	.	PUNCT
dpc-5921	111	1	high	high	ADJ
dpc-5921	111	2	rates	rate	NOUN
dpc-5921	111	3	of	of	ADP
dpc-5921	111	4	patient	patient	ADJ
dpc-5921	111	5	satisfaction	satisfaction	NOUN
dpc-5921	111	6	with	with	ADP
dpc-5921	111	7	tirbanibulin	tirbanibulin	PROPN
dpc-5921	111	8	(	(	PUNCT
dpc-5921	111	9	as	as	SCONJ
dpc-5921	111	10	assessed	assess	VERB
dpc-5921	111	11	by	by	ADP
dpc-5921	111	12	the	the	DET
dpc-5921	111	13	treatment	treatment	NOUN
dpc-5921	111	14	satisfaction	satisfaction	NOUN
dpc-5921	111	15	questionnaire	questionnaire	NOUN
dpc-5921	111	16	for	for	ADP
dpc-5921	111	17	medication	medication	NOUN
dpc-5921	111	18	)	)	PUNCT
dpc-5921	111	19	have	have	AUX
dpc-5921	111	20	also	also	ADV
dpc-5921	111	21	been	be	AUX
dpc-5921	111	22	reported	report	VERB
dpc-5921	111	23	,	,	PUNCT
dpc-5921	111	24	especially	especially	ADV
dpc-5921	111	25	in	in	ADP
dpc-5921	111	26	domains	domain	NOUN
dpc-5921	111	27	related	relate	VERB
dpc-5921	111	28	to	to	ADP
dpc-5921	111	29	treatment	treatment	NOUN
dpc-5921	111	30	tolerability	tolerability	NOUN
dpc-5921	111	31	and	and	CCONJ
dpc-5921	111	32	convenience	convenience	NOUN
dpc-5921	111	33	[	[	X
dpc-5921	111	34	10	10	NUM
dpc-5921	111	35	]	]	PUNCT
dpc-5921	111	36	.	.	PUNCT
dpc-5921	112	1	6	6	NUM
dpc-5921	112	2	review	review	NOUN
dpc-5921	112	3	|	|	ADV
dpc-5921	112	4	dermatol	dermatol	ADJ
dpc-5921	112	5	pract	pract	NOUN
dpc-5921	112	6	concept	concept	NOUN
dpc-5921	112	7	.	.	PUNCT
dpc-5921	113	1	2025;15(3):5921	2025;15(3):5921	NUM
dpc-5921	113	2	skin	skin	NOUN
dpc-5921	113	3	reactions	reaction	NOUN
dpc-5921	113	4	,	,	PUNCT
dpc-5921	113	5	and	and	CCONJ
dpc-5921	113	6	patient	patient	ADJ
dpc-5921	113	7	confusion	confusion	NOUN
dpc-5921	113	8	regarding	regard	VERB
dpc-5921	113	9	treatment	treatment	NOUN
dpc-5921	113	10	regimens	regimen	NOUN
dpc-5921	113	11	[	[	X
dpc-5921	113	12	37	37	NUM
dpc-5921	113	13	]	]	PUNCT
dpc-5921	113	14	.	.	PUNCT
dpc-5921	114	1	consistently	consistently	ADV
dpc-5921	114	2	with	with	ADP
dpc-5921	114	3	the	the	DET
dpc-5921	114	4	data	datum	NOUN
dpc-5921	114	5	reported	report	VERB
dpc-5921	114	6	in	in	ADP
dpc-5921	114	7	clinical	clinical	ADJ
dpc-5921	114	8	trials	trial	NOUN
dpc-5921	114	9	and	and	CCONJ
dpc-5921	114	10	real	real	ADJ
dpc-5921	114	11	-	-	PUNCT
dpc-5921	114	12	life	life	NOUN
dpc-5921	114	13	studies	study	NOUN
dpc-5921	114	14	,	,	PUNCT
dpc-5921	114	15	this	this	DET
dpc-5921	114	16	expert	expert	ADJ
dpc-5921	114	17	panel	panel	NOUN
dpc-5921	114	18	suggests	suggest	VERB
dpc-5921	114	19	that	that	SCONJ
dpc-5921	114	20	tirbanibulin	tirbanibulin	PROPN
dpc-5921	114	21	should	should	AUX
dpc-5921	114	22	be	be	AUX
dpc-5921	114	23	considered	consider	VERB
dpc-5921	114	24	as	as	ADP
dpc-5921	114	25	a	a	DET
dpc-5921	114	26	first	first	ADJ
dpc-5921	114	27	-	-	PUNCT
dpc-5921	114	28	line	line	NOUN
dpc-5921	114	29	treatment	treatment	NOUN
dpc-5921	114	30	for	for	ADP
dpc-5921	114	31	most	most	ADJ
dpc-5921	114	32	ak	ak	PROPN
dpc-5921	114	33	patients	patient	NOUN
dpc-5921	114	34	,	,	PUNCT
dpc-5921	114	35	both	both	CCONJ
dpc-5921	114	36	naïve	naïve	ADJ
dpc-5921	114	37	and	and	CCONJ
dpc-5921	114	38	previously	previously	ADV
dpc-5921	114	39	treated	treat	VERB
dpc-5921	114	40	,	,	PUNCT
dpc-5921	114	41	because	because	SCONJ
dpc-5921	114	42	of	of	ADP
dpc-5921	114	43	its	its	PRON
dpc-5921	114	44	efficacy	efficacy	NOUN
dpc-5921	114	45	,	,	PUNCT
dpc-5921	114	46	short	short	ADJ
dpc-5921	114	47	treatment	treatment	NOUN
dpc-5921	114	48	regimen	regiman	NOUN
dpc-5921	114	49	,	,	PUNCT
dpc-5921	114	50	and	and	CCONJ
dpc-5921	114	51	favorable	favorable	ADJ
dpc-5921	114	52	tolerability	tolerability	NOUN
dpc-5921	114	53	profile	profile	NOUN
dpc-5921	114	54	.	.	PUNCT
dpc-5921	115	1	as	as	SCONJ
dpc-5921	115	2	widely	widely	ADV
dpc-5921	115	3	acknowledged	acknowledge	VERB
dpc-5921	115	4	,	,	PUNCT
dpc-5921	115	5	appropriate	appropriate	ADJ
dpc-5921	115	6	management	management	NOUN
dpc-5921	115	7	of	of	ADP
dpc-5921	115	8	ak	ak	PROPN
dpc-5921	115	9	should	should	AUX
dpc-5921	115	10	consider	consider	VERB
dpc-5921	115	11	patient	patient	ADJ
dpc-5921	115	12	preferences	preference	NOUN
dpc-5921	115	13	,	,	PUNCT
dpc-5921	115	14	clinical	clinical	ADJ
dpc-5921	115	15	presentation	presentation	NOUN
dpc-5921	115	16	(	(	PUNCT
dpc-5921	115	17	including	include	VERB
dpc-5921	115	18	localization	localization	NOUN
dpc-5921	115	19	,	,	PUNCT
dpc-5921	115	20	extension	extension	NOUN
dpc-5921	115	21	and	and	CCONJ
dpc-5921	115	22	severity	severity	NOUN
dpc-5921	115	23	of	of	ADP
dpc-5921	115	24	lesions	lesion	NOUN
dpc-5921	115	25	and	and	CCONJ
dpc-5921	115	26	fc	fc	INTJ
dpc-5921	115	27	,	,	PUNCT
dpc-5921	115	28	duration	duration	NOUN
dpc-5921	115	29	and	and	CCONJ
dpc-5921	115	30	severity	severity	NOUN
dpc-5921	115	31	of	of	ADP
dpc-5921	115	32	symptoms	symptom	NOUN
dpc-5921	115	33	)	)	PUNCT
dpc-5921	115	34	and	and	CCONJ
dpc-5921	115	35	patient	patient	ADJ
dpc-5921	115	36	characteristics	characteristic	NOUN
dpc-5921	115	37	(	(	PUNCT
dpc-5921	115	38	e.g.	e.g.	ADV
dpc-5921	115	39	,	,	PUNCT
dpc-5921	115	40	general	general	ADJ
dpc-5921	115	41	health	health	NOUN
dpc-5921	115	42	,	,	PUNCT
dpc-5921	115	43	comorbidities	comorbiditie	NOUN
dpc-5921	115	44	,	,	PUNCT
dpc-5921	115	45	risk	risk	NOUN
dpc-5921	115	46	factors	factor	NOUN
dpc-5921	115	47	for	for	ADP
dpc-5921	115	48	skin	skin	NOUN
dpc-5921	115	49	cancer	cancer	NOUN
dpc-5921	115	50	)	)	PUNCT
dpc-5921	116	1	[	[	X
dpc-5921	116	2	4,12,27	4,12,27	NUM
dpc-5921	116	3	]	]	PUNCT
dpc-5921	116	4	.	.	PUNCT
dpc-5921	117	1	in	in	ADP
dpc-5921	117	2	the	the	DET
dpc-5921	117	3	expert	expert	NOUN
dpc-5921	117	4	panel	panel	NOUN
dpc-5921	117	5	’s	’s	PART
dpc-5921	117	6	experience	experience	NOUN
dpc-5921	117	7	,	,	PUNCT
dpc-5921	117	8	tirbanibulin	tirbanibulin	PROPN
dpc-5921	117	9	has	have	AUX
dpc-5921	117	10	been	be	AUX
dpc-5921	117	11	successfully	successfully	ADV
dpc-5921	117	12	used	use	VERB
dpc-5921	117	13	in	in	ADP
dpc-5921	117	14	a	a	DET
dpc-5921	117	15	wide	wide	ADJ
dpc-5921	117	16	range	range	NOUN
dpc-5921	117	17	of	of	ADP
dpc-5921	117	18	clinical	clinical	ADJ
dpc-5921	117	19	scenarios	scenario	NOUN
dpc-5921	117	20	,	,	PUNCT
dpc-5921	117	21	including	include	VERB
dpc-5921	117	22	isolated	isolated	ADJ
dpc-5921	117	23	or	or	CCONJ
dpc-5921	117	24	multiple	multiple	ADJ
dpc-5921	117	25	ak	ak	PROPN
dpc-5921	117	26	lesions	lesion	NOUN
dpc-5921	117	27	of	of	ADP
dpc-5921	117	28	varying	vary	VERB
dpc-5921	117	29	severity	severity	NOUN
dpc-5921	117	30	(	(	PUNCT
dpc-5921	117	31	olsen	olsen	NOUN
dpc-5921	117	32	grade	grade	NOUN
dpc-5921	117	33	i	i	PROPN
dpc-5921	117	34	and	and	CCONJ
dpc-5921	117	35	ii	ii	NOUN
dpc-5921	117	36	)	)	PUNCT
dpc-5921	117	37	located	locate	VERB
dpc-5921	117	38	in	in	ADP
dpc-5921	117	39	different	different	ADJ
dpc-5921	117	40	areas	area	NOUN
dpc-5921	117	41	of	of	ADP
dpc-5921	117	42	the	the	DET
dpc-5921	117	43	face	face	NOUN
dpc-5921	117	44	and	and	CCONJ
dpc-5921	117	45	scalp	scalp	NOUN
dpc-5921	117	46	,	,	PUNCT
dpc-5921	117	47	extensive	extensive	ADJ
dpc-5921	117	48	fc	fc	NOUN
dpc-5921	117	49	,	,	PUNCT
dpc-5921	117	50	patients	patient	NOUN
dpc-5921	117	51	who	who	PRON
dpc-5921	117	52	had	have	AUX
dpc-5921	117	53	received	receive	VERB
dpc-5921	117	54	multiple	multiple	ADJ
dpc-5921	117	55	ak	ak	PROPN
dpc-5921	117	56	therapies	therapy	NOUN
dpc-5921	117	57	,	,	PUNCT
dpc-5921	117	58	and	and	CCONJ
dpc-5921	117	59	those	those	PRON
dpc-5921	117	60	with	with	ADP
dpc-5921	117	61	a	a	DET
dpc-5921	117	62	history	history	NOUN
dpc-5921	117	63	of	of	ADP
dpc-5921	117	64	chronic	chronic	ADJ
dpc-5921	117	65	sun	sun	NOUN
dpc-5921	117	66	damage	damage	NOUN
dpc-5921	117	67	.	.	PUNCT
dpc-5921	118	1	in	in	ADP
dpc-5921	118	2	particular	particular	ADJ
dpc-5921	118	3	,	,	PUNCT
dpc-5921	118	4	tirbanibulin	tirbanibulin	PRON
dpc-5921	118	5	therapy	therapy	NOUN
dpc-5921	118	6	has	have	AUX
dpc-5921	118	7	been	be	AUX
dpc-5921	118	8	selected	select	VERB
dpc-5921	118	9	as	as	ADP
dpc-5921	118	10	the	the	DET
dpc-5921	118	11	treatment	treatment	NOUN
dpc-5921	118	12	of	of	ADP
dpc-5921	118	13	choice	choice	NOUN
dpc-5921	118	14	in	in	ADP
dpc-5921	118	15	subjects	subject	NOUN
dpc-5921	118	16	with	with	ADP
dpc-5921	118	17	comorbidities	comorbiditie	NOUN
dpc-5921	118	18	and	and	CCONJ
dpc-5921	118	19	those	those	PRON
dpc-5921	118	20	with	with	ADP
dpc-5921	118	21	a	a	DET
dpc-5921	118	22	history	history	NOUN
dpc-5921	118	23	of	of	ADP
dpc-5921	118	24	skin	skin	NOUN
dpc-5921	118	25	cancer	cancer	NOUN
dpc-5921	118	26	owing	owe	VERB
dpc-5921	118	27	to	to	ADP
dpc-5921	118	28	its	its	PRON
dpc-5921	118	29	tolerability	tolerability	NOUN
dpc-5921	118	30	and	and	CCONJ
dpc-5921	118	31	lack	lack	NOUN
dpc-5921	118	32	of	of	ADP
dpc-5921	118	33	systemic	systemic	ADJ
dpc-5921	118	34	adverse	adverse	ADJ
dpc-5921	118	35	events	event	NOUN
dpc-5921	118	36	.	.	PUNCT
dpc-5921	119	1	the	the	DET
dpc-5921	119	2	efficacy	efficacy	NOUN
dpc-5921	119	3	of	of	ADP
dpc-5921	119	4	tirbanibulin	tirbanibulin	PROPN
dpc-5921	119	5	appears	appear	VERB
dpc-5921	119	6	to	to	PART
dpc-5921	119	7	be	be	AUX
dpc-5921	119	8	maintained	maintain	VERB
dpc-5921	119	9	in	in	ADP
dpc-5921	119	10	difficult	difficult	ADJ
dpc-5921	119	11	-	-	PUNCT
dpc-5921	119	12	to	to	ADP
dpc-5921	119	13	-	-	PUNCT
dpc-5921	119	14	treat	treat	NOUN
dpc-5921	119	15	sites	site	NOUN
dpc-5921	119	16	,	,	PUNCT
dpc-5921	119	17	including	include	VERB
dpc-5921	119	18	ears	ear	NOUN
dpc-5921	119	19	,	,	PUNCT
dpc-5921	119	20	lips	lip	NOUN
dpc-5921	119	21	,	,	PUNCT
dpc-5921	119	22	and	and	CCONJ
dpc-5921	119	23	limbs	limb	NOUN
dpc-5921	119	24	,	,	PUNCT
dpc-5921	119	25	and	and	CCONJ
dpc-5921	119	26	in	in	ADP
dpc-5921	119	27	areas	area	NOUN
dpc-5921	119	28	with	with	ADP
dpc-5921	119	29	adnexa	adnexa	ADJ
dpc-5921	119	30	or	or	CCONJ
dpc-5921	119	31	pigmented	pigmented	ADJ
dpc-5921	119	32	lesions	lesion	NOUN
dpc-5921	119	33	.	.	PUNCT
dpc-5921	120	1	examples	example	NOUN
dpc-5921	120	2	of	of	ADP
dpc-5921	120	3	tirbanibulin	tirbanibulin	ADV
dpc-5921	120	4	-	-	PUNCT
dpc-5921	120	5	treated	treat	VERB
dpc-5921	120	6	clinical	clinical	ADJ
dpc-5921	120	7	cases	case	NOUN
dpc-5921	120	8	with	with	ADP
dpc-5921	120	9	various	various	ADJ
dpc-5921	120	10	ak	ak	PROPN
dpc-5921	120	11	presentations	presentation	NOUN
dpc-5921	120	12	are	be	AUX
dpc-5921	120	13	illustrated	illustrate	VERB
dpc-5921	120	14	in	in	ADP
dpc-5921	120	15	figures	figure	NOUN
dpc-5921	120	16	2–5	2–5	PROPN
dpc-5921	120	17	.	.	PUNCT
dpc-5921	121	1	even	even	ADV
dpc-5921	121	2	in	in	ADP
dpc-5921	121	3	cases	case	NOUN
dpc-5921	121	4	where	where	SCONJ
dpc-5921	121	5	total	total	ADJ
dpc-5921	121	6	clearance	clearance	NOUN
dpc-5921	121	7	of	of	ADP
dpc-5921	121	8	ak	ak	PROPN
dpc-5921	121	9	lesions	lesion	NOUN
dpc-5921	121	10	was	be	AUX
dpc-5921	121	11	not	not	PART
dpc-5921	121	12	achieved	achieve	VERB
dpc-5921	121	13	,	,	PUNCT
dpc-5921	121	14	a	a	DET
dpc-5921	121	15	substantial	substantial	ADJ
dpc-5921	121	16	clinical	clinical	ADJ
dpc-5921	121	17	improvement	improvement	NOUN
dpc-5921	121	18	in	in	ADP
dpc-5921	121	19	both	both	DET
dpc-5921	121	20	lesions	lesion	NOUN
dpc-5921	121	21	and	and	CCONJ
dpc-5921	121	22	fc	fc	PROPN
dpc-5921	121	23	was	be	AUX
dpc-5921	121	24	observed	observe	VERB
dpc-5921	121	25	.	.	PUNCT
dpc-5921	122	1	according	accord	VERB
dpc-5921	122	2	to	to	ADP
dpc-5921	122	3	the	the	DET
dpc-5921	122	4	authors	author	NOUN
dpc-5921	122	5	’	’	PART
dpc-5921	122	6	clinical	clinical	ADJ
dpc-5921	122	7	experience	experience	NOUN
dpc-5921	122	8	,	,	PUNCT
dpc-5921	122	9	tirbanibulin	tirbanibulin	PROPN
dpc-5921	122	10	therapy	therapy	NOUN
dpc-5921	122	11	is	be	AUX
dpc-5921	122	12	readily	readily	ADV
dpc-5921	122	13	accepted	accept	VERB
dpc-5921	122	14	by	by	ADP
dpc-5921	122	15	patients	patient	NOUN
dpc-5921	122	16	,	,	PUNCT
dpc-5921	122	17	with	with	ADP
dpc-5921	122	18	a	a	DET
dpc-5921	122	19	high	high	ADJ
dpc-5921	122	20	degree	degree	NOUN
dpc-5921	122	21	of	of	ADP
dpc-5921	122	22	satisfaction	satisfaction	NOUN
dpc-5921	122	23	and	and	CCONJ
dpc-5921	122	24	treatment	treatment	NOUN
dpc-5921	122	25	compliance	compliance	NOUN
dpc-5921	122	26	.	.	PUNCT
dpc-5921	123	1	local	local	ADJ
dpc-5921	123	2	reactions	reaction	NOUN
dpc-5921	123	3	(	(	PUNCT
dpc-5921	123	4	mostly	mostly	ADV
dpc-5921	123	5	erythema	erythema	ADJ
dpc-5921	123	6	and	and	CCONJ
dpc-5921	123	7	flaking	flake	VERB
dpc-5921	123	8	/	/	SYM
dpc-5921	123	9	scaling	scaling	NOUN
dpc-5921	123	10	)	)	PUNCT
dpc-5921	123	11	are	be	AUX
dpc-5921	123	12	generally	generally	ADV
dpc-5921	123	13	mild	mild	ADJ
dpc-5921	123	14	,	,	PUNCT
dpc-5921	123	15	peak	peak	NOUN
dpc-5921	123	16	at	at	ADP
dpc-5921	123	17	approximately	approximately	ADV
dpc-5921	123	18	day	day	NOUN
dpc-5921	123	19	8	8	NUM
dpc-5921	123	20	after	after	ADP
dpc-5921	123	21	treatment	treatment	NOUN
dpc-5921	123	22	initiation	initiation	NOUN
dpc-5921	123	23	(	(	PUNCT
dpc-5921	123	24	consistently	consistently	ADV
dpc-5921	123	25	with	with	ADP
dpc-5921	123	26	clinical	clinical	ADJ
dpc-5921	123	27	study	study	NOUN
dpc-5921	123	28	reports	report	NOUN
dpc-5921	123	29	)	)	PUNCT
dpc-5921	123	30	,	,	PUNCT
dpc-5921	123	31	and	and	CCONJ
dpc-5921	123	32	resolve	resolve	VERB
dpc-5921	123	33	spontaneously	spontaneously	ADV
dpc-5921	123	34	over	over	ADP
dpc-5921	123	35	an	an	DET
dpc-5921	123	36	average	average	NOUN
dpc-5921	123	37	of	of	ADP
dpc-5921	123	38	10	10	NUM
dpc-5921	123	39	days	day	NOUN
dpc-5921	123	40	,	,	PUNCT
dpc-5921	123	41	without	without	ADP
dpc-5921	123	42	sequelae	sequelae	PROPN
dpc-5921	123	43	.	.	PUNCT
dpc-5921	124	1	some	some	DET
dpc-5921	124	2	patients	patient	NOUN
dpc-5921	124	3	experience	experience	VERB
dpc-5921	124	4	a	a	DET
dpc-5921	124	5	burning	burning	NOUN
dpc-5921	124	6	or	or	CCONJ
dpc-5921	124	7	itching	itching	NOUN
dpc-5921	124	8	sensation	sensation	NOUN
dpc-5921	124	9	at	at	ADP
dpc-5921	124	10	the	the	DET
dpc-5921	124	11	application	application	NOUN
dpc-5921	124	12	site	site	NOUN
dpc-5921	124	13	.	.	PUNCT
dpc-5921	125	1	the	the	DET
dpc-5921	125	2	intensity	intensity	NOUN
dpc-5921	125	3	of	of	ADP
dpc-5921	125	4	local	local	ADJ
dpc-5921	125	5	reactions	reaction	NOUN
dpc-5921	125	6	seems	seem	VERB
dpc-5921	125	7	to	to	PART
dpc-5921	125	8	be	be	AUX
dpc-5921	125	9	correlated	correlate	VERB
dpc-5921	125	10	to	to	ADP
dpc-5921	125	11	the	the	DET
dpc-5921	125	12	extent	extent	NOUN
dpc-5921	125	13	of	of	ADP
dpc-5921	125	14	inflammation	inflammation	NOUN
dpc-5921	125	15	and	and	CCONJ
dpc-5921	125	16	photodamage	photodamage	NOUN
dpc-5921	125	17	in	in	ADP
dpc-5921	125	18	the	the	DET
dpc-5921	125	19	treated	treat	VERB
dpc-5921	125	20	field	field	NOUN
dpc-5921	125	21	(	(	PUNCT
dpc-5921	125	22	figure	figure	NOUN
dpc-5921	125	23	3	3	NUM
dpc-5921	125	24	)	)	PUNCT
dpc-5921	125	25	.	.	PUNCT
dpc-5921	126	1	however	however	ADV
dpc-5921	126	2	,	,	PUNCT
dpc-5921	126	3	severe	severe	ADJ
dpc-5921	126	4	local	local	ADJ
dpc-5921	126	5	reactions	reaction	NOUN
dpc-5921	126	6	such	such	ADJ
dpc-5921	126	7	as	as	ADP
dpc-5921	126	8	swelling	swell	VERB
dpc-5921	126	9	or	or	CCONJ
dpc-5921	126	10	erosion	erosion	NOUN
dpc-5921	126	11	/	/	SYM
dpc-5921	126	12	ulceration	ulceration	NOUN
dpc-5921	126	13	are	be	AUX
dpc-5921	126	14	rarely	rarely	ADV
dpc-5921	126	15	observed	observe	VERB
dpc-5921	126	16	.	.	PUNCT
dpc-5921	127	1	in	in	ADP
dpc-5921	127	2	addition	addition	NOUN
dpc-5921	127	3	to	to	ADP
dpc-5921	127	4	clearing	clear	VERB
dpc-5921	127	5	or	or	CCONJ
dpc-5921	127	6	reducing	reduce	VERB
dpc-5921	127	7	ak	ak	PROPN
dpc-5921	127	8	signs	sign	NOUN
dpc-5921	127	9	,	,	PUNCT
dpc-5921	127	10	tirbanibulin	tirbanibulin	DET
dpc-5921	127	11	treatment	treatment	NOUN
dpc-5921	127	12	was	be	AUX
dpc-5921	127	13	also	also	ADV
dpc-5921	127	14	found	find	VERB
dpc-5921	127	15	to	to	PART
dpc-5921	127	16	be	be	AUX
dpc-5921	127	17	associated	associate	VERB
dpc-5921	127	18	with	with	ADP
dpc-5921	127	19	cosmetic	cosmetic	ADJ
dpc-5921	127	20	benefits	benefit	NOUN
dpc-5921	127	21	,	,	PUNCT
dpc-5921	127	22	such	such	ADJ
dpc-5921	127	23	as	as	ADP
dpc-5921	127	24	improvement	improvement	NOUN
dpc-5921	127	25	in	in	ADP
dpc-5921	127	26	skin	skin	NOUN
dpc-5921	127	27	quality	quality	NOUN
dpc-5921	127	28	and	and	CCONJ
dpc-5921	127	29	texture	texture	NOUN
dpc-5921	127	30	and	and	CCONJ
dpc-5921	127	31	a	a	DET
dpc-5921	127	32	more	more	ADV
dpc-5921	127	33	uniform	uniform	ADJ
dpc-5921	127	34	complexion	complexion	NOUN
dpc-5921	127	35	(	(	PUNCT
dpc-5921	127	36	figures	figure	NOUN
dpc-5921	127	37	4	4	NUM
dpc-5921	127	38	and	and	CCONJ
dpc-5921	127	39	5	5	NUM
dpc-5921	127	40	)	)	PUNCT
dpc-5921	127	41	.	.	PUNCT
dpc-5921	128	1	these	these	DET
dpc-5921	128	2	emerging	emerge	VERB
dpc-5921	128	3	potential	potential	ADJ
dpc-5921	128	4	effects	effect	NOUN
dpc-5921	128	5	of	of	ADP
dpc-5921	128	6	tirbanibulin	tirbanibulin	PROPN
dpc-5921	128	7	in	in	ADP
dpc-5921	128	8	targeting	target	VERB
dpc-5921	128	9	signs	sign	NOUN
dpc-5921	128	10	of	of	ADP
dpc-5921	128	11	skin	skin	NOUN
dpc-5921	128	12	aging	aging	NOUN
dpc-5921	128	13	,	,	PUNCT
dpc-5921	128	14	especially	especially	ADV
dpc-5921	128	15	hyperpigmentation	hyperpigmentation	NOUN
dpc-5921	128	16	,	,	PUNCT
dpc-5921	128	17	have	have	AUX
dpc-5921	128	18	been	be	AUX
dpc-5921	128	19	investigated	investigate	VERB
dpc-5921	128	20	in	in	ADP
dpc-5921	128	21	recent	recent	ADJ
dpc-5921	128	22	preliminary	preliminary	ADJ
dpc-5921	128	23	studies	study	NOUN
dpc-5921	128	24	[	[	X
dpc-5921	128	25	38,39	38,39	NOUN
dpc-5921	128	26	]	]	X
dpc-5921	128	27	.	.	PUNCT
dpc-5921	129	1	in	in	ADP
dpc-5921	129	2	particular	particular	ADJ
dpc-5921	129	3	,	,	PUNCT
dpc-5921	129	4	tirbanibulin	tirbanibulin	PROPN
dpc-5921	129	5	,	,	PUNCT
dpc-5921	129	6	unlike	unlike	ADP
dpc-5921	129	7	other	other	ADJ
dpc-5921	129	8	ak	ak	PROPN
dpc-5921	129	9	therapies	therapy	NOUN
dpc-5921	129	10	,	,	PUNCT
dpc-5921	129	11	appears	appear	VERB
dpc-5921	129	12	to	to	PART
dpc-5921	129	13	exert	exert	VERB
dpc-5921	129	14	a	a	DET
dpc-5921	129	15	skin	skin	NOUN
dpc-5921	129	16	-	-	PUNCT
dpc-5921	129	17	lightening	lighten	VERB
dpc-5921	129	18	effect	effect	NOUN
dpc-5921	129	19	on	on	ADP
dpc-5921	129	20	solar	solar	ADJ
dpc-5921	129	21	lentigines	lentigo	NOUN
dpc-5921	129	22	,	,	PUNCT
dpc-5921	129	23	hyperpigmented	hyperpigmented	ADJ
dpc-5921	129	24	areas	area	NOUN
dpc-5921	129	25	that	that	PRON
dpc-5921	129	26	are	be	AUX
dpc-5921	129	27	frequently	frequently	ADV
dpc-5921	129	28	observed	observe	VERB
dpc-5921	129	29	in	in	ADP
dpc-5921	129	30	the	the	DET
dpc-5921	129	31	context	context	NOUN
dpc-5921	129	32	of	of	ADP
dpc-5921	129	33	ak	ak	PROPN
dpc-5921	129	34	and	and	CCONJ
dpc-5921	129	35	fc	fc	VERB
dpc-5921	130	1	[	[	X
dpc-5921	130	2	39	39	NUM
dpc-5921	130	3	]	]	PUNCT
dpc-5921	130	4	.	.	PUNCT
dpc-5921	131	1	although	although	SCONJ
dpc-5921	131	2	the	the	DET
dpc-5921	131	3	mechanisms	mechanism	NOUN
dpc-5921	131	4	of	of	ADP
dpc-5921	131	5	action	action	NOUN
dpc-5921	131	6	underlying	underlie	VERB
dpc-5921	131	7	these	these	DET
dpc-5921	131	8	effects	effect	NOUN
dpc-5921	131	9	need	need	VERB
dpc-5921	131	10	to	to	PART
dpc-5921	131	11	be	be	AUX
dpc-5921	131	12	further	far	ADV
dpc-5921	131	13	elucidated	elucidate	VERB
dpc-5921	131	14	,	,	PUNCT
dpc-5921	131	15	the	the	DET
dpc-5921	131	16	potential	potential	NOUN
dpc-5921	131	17	the	the	DET
dpc-5921	131	18	efficacy	efficacy	NOUN
dpc-5921	131	19	and	and	CCONJ
dpc-5921	131	20	favorable	favorable	ADJ
dpc-5921	131	21	tolerability	tolerability	NOUN
dpc-5921	131	22	profile	profile	NOUN
dpc-5921	131	23	of	of	ADP
dpc-5921	131	24	tirbanibulin	tirbanibulin	PROPN
dpc-5921	131	25	are	be	AUX
dpc-5921	131	26	believed	believe	VERB
dpc-5921	131	27	to	to	PART
dpc-5921	131	28	be	be	AUX
dpc-5921	131	29	related	relate	VERB
dpc-5921	131	30	to	to	ADP
dpc-5921	131	31	the	the	DET
dpc-5921	131	32	novel	novel	ADJ
dpc-5921	131	33	mechanism	mechanism	NOUN
dpc-5921	131	34	of	of	ADP
dpc-5921	131	35	action	action	NOUN
dpc-5921	131	36	of	of	ADP
dpc-5921	131	37	this	this	DET
dpc-5921	131	38	molecule	molecule	NOUN
dpc-5921	131	39	.	.	PUNCT
dpc-5921	132	1	preclinical	preclinical	ADJ
dpc-5921	132	2	studies	study	NOUN
dpc-5921	132	3	show	show	VERB
dpc-5921	132	4	that	that	SCONJ
dpc-5921	132	5	tirbanibulin	tirbanibulin	PROPN
dpc-5921	132	6	,	,	PUNCT
dpc-5921	132	7	a	a	DET
dpc-5921	132	8	potent	potent	ADJ
dpc-5921	132	9	antiproliferative	antiproliferative	ADJ
dpc-5921	132	10	agent	agent	NOUN
dpc-5921	132	11	,	,	PUNCT
dpc-5921	132	12	induces	induce	VERB
dpc-5921	132	13	cell	cell	NOUN
dpc-5921	132	14	cycle	cycle	NOUN
dpc-5921	132	15	arrest	arrest	NOUN
dpc-5921	132	16	at	at	ADP
dpc-5921	132	17	g2	g2	PROPN
dpc-5921	132	18	/	/	SYM
dpc-5921	132	19	m	m	PROPN
dpc-5921	132	20	phase	phase	NOUN
dpc-5921	132	21	and	and	CCONJ
dpc-5921	132	22	triggers	trigger	NOUN
dpc-5921	132	23	programmed	program	VERB
dpc-5921	132	24	cell	cell	NOUN
dpc-5921	132	25	death	death	NOUN
dpc-5921	132	26	of	of	ADP
dpc-5921	132	27	keratinocytes	keratinocyte	NOUN
dpc-5921	132	28	(	(	PUNCT
dpc-5921	132	29	via	via	ADP
dpc-5921	132	30	activation	activation	NOUN
dpc-5921	132	31	of	of	ADP
dpc-5921	132	32	intrinsic	intrinsic	ADJ
dpc-5921	132	33	and	and	CCONJ
dpc-5921	132	34	extrinsic	extrinsic	ADJ
dpc-5921	132	35	apoptotic	apoptotic	ADJ
dpc-5921	132	36	pathways	pathway	NOUN
dpc-5921	132	37	)	)	PUNCT
dpc-5921	132	38	by	by	ADP
dpc-5921	132	39	reversibly	reversibly	ADV
dpc-5921	132	40	binding	bind	VERB
dpc-5921	132	41	to	to	ADP
dpc-5921	132	42	tubulin	tubulin	NOUN
dpc-5921	132	43	,	,	PUNCT
dpc-5921	132	44	thus	thus	ADV
dpc-5921	132	45	inhibiting	inhibit	VERB
dpc-5921	132	46	tubulin	tubulin	NOUN
dpc-5921	132	47	polymerization	polymerization	NOUN
dpc-5921	132	48	,	,	PUNCT
dpc-5921	132	49	and	and	CCONJ
dpc-5921	132	50	by	by	ADP
dpc-5921	132	51	disrupting	disrupt	VERB
dpc-5921	132	52	src	src	NOUN
dpc-5921	132	53	intracellular	intracellular	ADJ
dpc-5921	132	54	trafficking	trafficking	NOUN
dpc-5921	132	55	and	and	CCONJ
dpc-5921	132	56	src	src	NOUN
dpc-5921	132	57	-	-	PUNCT
dpc-5921	132	58	mediated	mediate	VERB
dpc-5921	132	59	signaling	signaling	NOUN
dpc-5921	132	60	.	.	PUNCT
dpc-5921	133	1	another	another	DET
dpc-5921	133	2	possible	possible	ADJ
dpc-5921	133	3	antiproliferative	antiproliferative	ADJ
dpc-5921	133	4	mechanism	mechanism	NOUN
dpc-5921	133	5	is	be	AUX
dpc-5921	133	6	the	the	DET
dpc-5921	133	7	induction	induction	NOUN
dpc-5921	133	8	of	of	ADP
dpc-5921	133	9	tumor	tumor	NOUN
dpc-5921	133	10	suppressor	suppressor	NOUN
dpc-5921	133	11	p53	p53	NOUN
dpc-5921	133	12	expression	expression	NOUN
dpc-5921	133	13	.	.	PUNCT
dpc-5921	134	1	tirbanibulin	tirbanibulin	PROPN
dpc-5921	134	2	antiproliferative	antiproliferative	ADJ
dpc-5921	134	3	effects	effect	NOUN
dpc-5921	134	4	have	have	AUX
dpc-5921	134	5	been	be	AUX
dpc-5921	134	6	demonstrated	demonstrate	VERB
dpc-5921	134	7	in	in	ADP
dpc-5921	134	8	several	several	ADJ
dpc-5921	134	9	tumor	tumor	NOUN
dpc-5921	134	10	cell	cell	NOUN
dpc-5921	134	11	lines	line	NOUN
dpc-5921	134	12	,	,	PUNCT
dpc-5921	134	13	including	include	VERB
dpc-5921	134	14	scc	scc	NOUN
dpc-5921	134	15	,	,	PUNCT
dpc-5921	134	16	suggesting	suggest	VERB
dpc-5921	134	17	that	that	SCONJ
dpc-5921	134	18	keratinocytes	keratinocyte	NOUN
dpc-5921	134	19	with	with	ADP
dpc-5921	134	20	an	an	DET
dpc-5921	134	21	aberrant	aberrant	ADJ
dpc-5921	134	22	cell	cell	NOUN
dpc-5921	134	23	growth	growth	NOUN
dpc-5921	134	24	rate	rate	NOUN
dpc-5921	134	25	may	may	AUX
dpc-5921	134	26	be	be	AUX
dpc-5921	134	27	selectively	selectively	ADV
dpc-5921	134	28	targeted	target	VERB
dpc-5921	134	29	by	by	ADP
dpc-5921	134	30	tirbanibulin	tirbanibulin	PROPN
dpc-5921	135	1	[	[	X
dpc-5921	135	2	32,33	32,33	NUM
dpc-5921	135	3	]	]	PUNCT
dpc-5921	135	4	.	.	PUNCT
dpc-5921	136	1	as	as	ADP
dpc-5921	136	2	for	for	ADP
dpc-5921	136	3	the	the	DET
dpc-5921	136	4	mechanisms	mechanism	NOUN
dpc-5921	136	5	accounting	account	VERB
dpc-5921	136	6	for	for	ADP
dpc-5921	136	7	tolerability	tolerability	NOUN
dpc-5921	136	8	,	,	PUNCT
dpc-5921	136	9	tirbanibulin	tirbanibulin	PROPN
dpc-5921	136	10	displayed	display	VERB
dpc-5921	136	11	an	an	DET
dpc-5921	136	12	apoptotic	apoptotic	ADJ
dpc-5921	136	13	effect	effect	NOUN
dpc-5921	136	14	without	without	ADP
dpc-5921	136	15	inducing	induce	VERB
dpc-5921	136	16	overt	overt	ADJ
dpc-5921	136	17	toxicity	toxicity	NOUN
dpc-5921	136	18	in	in	ADP
dpc-5921	136	19	vitro	vitro	X
dpc-5921	136	20	owing	owe	VERB
dpc-5921	136	21	to	to	ADP
dpc-5921	136	22	its	its	PRON
dpc-5921	136	23	fully	fully	ADV
dpc-5921	136	24	reversible	reversible	ADJ
dpc-5921	136	25	binding	binding	NOUN
dpc-5921	136	26	to	to	ADP
dpc-5921	136	27	tubulin	tubulin	NOUN
dpc-5921	136	28	[	[	X
dpc-5921	136	29	34	34	NUM
dpc-5921	136	30	]	]	PUNCT
dpc-5921	136	31	.	.	PUNCT
dpc-5921	137	1	the	the	DET
dpc-5921	137	2	induction	induction	NOUN
dpc-5921	137	3	of	of	ADP
dpc-5921	137	4	apoptosis	apoptosis	NOUN
dpc-5921	137	5	has	have	AUX
dpc-5921	137	6	also	also	ADV
dpc-5921	137	7	been	be	AUX
dpc-5921	137	8	demonstrated	demonstrate	VERB
dpc-5921	137	9	in	in	ADP
dpc-5921	137	10	a	a	DET
dpc-5921	137	11	study	study	NOUN
dpc-5921	137	12	using	use	VERB
dpc-5921	137	13	line	line	NOUN
dpc-5921	137	14	-	-	PUNCT
dpc-5921	137	15	field	field	NOUN
dpc-5921	137	16	confocal	confocal	ADJ
dpc-5921	137	17	optical	optical	ADJ
dpc-5921	137	18	coherence	coherence	NOUN
dpc-5921	137	19	tomography	tomography	NOUN
dpc-5921	137	20	and	and	CCONJ
dpc-5921	137	21	confirmed	confirm	VERB
dpc-5921	137	22	by	by	ADP
dpc-5921	137	23	histopathology	histopathology	NOUN
dpc-5921	137	24	[	[	X
dpc-5921	137	25	35	35	NUM
dpc-5921	137	26	]	]	PUNCT
dpc-5921	137	27	.	.	PUNCT
dpc-5921	138	1	the	the	DET
dpc-5921	138	2	severe	severe	ADJ
dpc-5921	138	3	adverse	adverse	ADJ
dpc-5921	138	4	local	local	ADJ
dpc-5921	138	5	reactions	reaction	NOUN
dpc-5921	138	6	caused	cause	VERB
dpc-5921	138	7	by	by	ADP
dpc-5921	138	8	many	many	ADJ
dpc-5921	138	9	ak	ak	PROPN
dpc-5921	138	10	treatments	treatment	NOUN
dpc-5921	138	11	are	be	AUX
dpc-5921	138	12	known	know	VERB
dpc-5921	138	13	to	to	PART
dpc-5921	138	14	be	be	AUX
dpc-5921	138	15	triggered	trigger	VERB
dpc-5921	138	16	by	by	ADP
dpc-5921	138	17	the	the	DET
dpc-5921	138	18	release	release	NOUN
dpc-5921	138	19	of	of	ADP
dpc-5921	138	20	pro	pro	ADJ
dpc-5921	138	21	-	-	ADJ
dpc-5921	138	22	inflammatory	inflammatory	ADJ
dpc-5921	138	23	cytokines	cytokine	NOUN
dpc-5921	138	24	such	such	ADJ
dpc-5921	138	25	as	as	ADP
dpc-5921	138	26	tumor	tumor	NOUN
dpc-5921	138	27	necrosis	necrosis	NOUN
dpc-5921	138	28	factor	factor	NOUN
dpc-5921	138	29	-	-	PUNCT
dpc-5921	138	30	α	α	X
dpc-5921	138	31	(	(	PUNCT
dpc-5921	138	32	tnf	tnf	PROPN
dpc-5921	138	33	-	-	PUNCT
dpc-5921	138	34	α	α	NOUN
dpc-5921	138	35	)	)	PUNCT
dpc-5921	138	36	and	and	CCONJ
dpc-5921	138	37	interleukin-8	interleukin-8	NUM
dpc-5921	138	38	(	(	PUNCT
dpc-5921	138	39	il-8	il-8	NOUN
dpc-5921	138	40	)	)	PUNCT
dpc-5921	138	41	.	.	PUNCT
dpc-5921	139	1	notably	notably	ADV
dpc-5921	139	2	,	,	PUNCT
dpc-5921	139	3	proinflammatory	proinflammatory	ADJ
dpc-5921	139	4	response	response	NOUN
dpc-5921	139	5	assays	assay	NOUN
dpc-5921	139	6	show	show	VERB
dpc-5921	139	7	that	that	SCONJ
dpc-5921	139	8	tirbanibulin	tirbanibulin	PROPN
dpc-5921	139	9	induces	induce	VERB
dpc-5921	139	10	only	only	ADV
dpc-5921	139	11	a	a	DET
dpc-5921	139	12	small	small	ADJ
dpc-5921	139	13	increase	increase	NOUN
dpc-5921	139	14	in	in	ADP
dpc-5921	139	15	il-8	il-8	NOUN
dpc-5921	139	16	,	,	PUNCT
dpc-5921	139	17	unlike	unlike	ADP
dpc-5921	139	18	the	the	DET
dpc-5921	139	19	significant	significant	ADJ
dpc-5921	139	20	increase	increase	NOUN
dpc-5921	139	21	in	in	ADP
dpc-5921	139	22	both	both	PRON
dpc-5921	139	23	tnf	tnf	PROPN
dpc-5921	139	24	-	-	PUNCT
dpc-5921	139	25	α	α	PROPN
dpc-5921	139	26	and	and	CCONJ
dpc-5921	139	27	il-8	il-8	NOUN
dpc-5921	139	28	caused	cause	VERB
dpc-5921	139	29	by	by	ADP
dpc-5921	139	30	5	5	NUM
dpc-5921	139	31	-	-	PUNCT
dpc-5921	139	32	fluorouracil	fluorouracil	NOUN
dpc-5921	139	33	[	[	X
dpc-5921	139	34	32	32	NUM
dpc-5921	139	35	]	]	PUNCT
dpc-5921	139	36	.	.	PUNCT
dpc-5921	140	1	these	these	DET
dpc-5921	140	2	data	datum	NOUN
dpc-5921	140	3	suggest	suggest	VERB
dpc-5921	140	4	a	a	DET
dpc-5921	140	5	milder	mild	ADJ
dpc-5921	140	6	pro	pro	ADJ
dpc-5921	140	7	-	-	ADJ
dpc-5921	140	8	inflammatory	inflammatory	ADJ
dpc-5921	140	9	effect	effect	NOUN
dpc-5921	140	10	of	of	ADP
dpc-5921	140	11	this	this	DET
dpc-5921	140	12	molecule	molecule	NOUN
dpc-5921	140	13	compared	compare	VERB
dpc-5921	140	14	with	with	ADP
dpc-5921	140	15	5	5	NUM
dpc-5921	140	16	-	-	PUNCT
dpc-5921	140	17	fluorouracil	fluorouracil	NOUN
dpc-5921	140	18	,	,	PUNCT
dpc-5921	140	19	which	which	PRON
dpc-5921	140	20	could	could	AUX
dpc-5921	140	21	explain	explain	VERB
dpc-5921	140	22	the	the	DET
dpc-5921	140	23	favorable	favorable	ADJ
dpc-5921	140	24	tolerability	tolerability	NOUN
dpc-5921	140	25	and	and	CCONJ
dpc-5921	140	26	safety	safety	NOUN
dpc-5921	140	27	profile	profile	NOUN
dpc-5921	140	28	observed	observe	VERB
dpc-5921	140	29	in	in	ADP
dpc-5921	140	30	tirbanibulin	tirbanibulin	ADV
dpc-5921	140	31	-	-	PUNCT
dpc-5921	140	32	treated	treat	VERB
dpc-5921	140	33	patients	patient	NOUN
dpc-5921	140	34	.	.	PUNCT
dpc-5921	141	1	patient	patient	ADJ
dpc-5921	141	2	selection	selection	NOUN
dpc-5921	141	3	and	and	CCONJ
dpc-5921	141	4	clinical	clinical	ADJ
dpc-5921	141	5	scenarios	scenario	NOUN
dpc-5921	141	6	as	as	SCONJ
dpc-5921	141	7	demonstrated	demonstrate	VERB
dpc-5921	141	8	in	in	ADP
dpc-5921	141	9	clinical	clinical	ADJ
dpc-5921	141	10	trials	trial	NOUN
dpc-5921	141	11	and	and	CCONJ
dpc-5921	141	12	real	real	ADJ
dpc-5921	141	13	-	-	PUNCT
dpc-5921	141	14	life	life	NOUN
dpc-5921	141	15	studies	study	NOUN
dpc-5921	141	16	,	,	PUNCT
dpc-5921	141	17	tirbanibulin	tirbanibulin	PROPN
dpc-5921	141	18	is	be	AUX
dpc-5921	141	19	effective	effective	ADJ
dpc-5921	141	20	in	in	ADP
dpc-5921	141	21	achieving	achieve	VERB
dpc-5921	141	22	high	high	ADJ
dpc-5921	141	23	clearance	clearance	NOUN
dpc-5921	141	24	rates	rate	NOUN
dpc-5921	141	25	of	of	ADP
dpc-5921	141	26	ak	ak	PROPN
dpc-5921	141	27	lesions	lesion	NOUN
dpc-5921	141	28	,	,	PUNCT
dpc-5921	141	29	with	with	ADP
dpc-5921	141	30	fewer	few	ADJ
dpc-5921	141	31	severe	severe	ADJ
dpc-5921	141	32	local	local	ADJ
dpc-5921	141	33	skin	skin	NOUN
dpc-5921	141	34	reactions	reaction	NOUN
dpc-5921	141	35	compared	compare	VERB
dpc-5921	141	36	with	with	ADP
dpc-5921	141	37	other	other	ADJ
dpc-5921	141	38	commonly	commonly	ADV
dpc-5921	141	39	used	use	VERB
dpc-5921	141	40	topical	topical	ADJ
dpc-5921	141	41	treatments	treatment	NOUN
dpc-5921	141	42	for	for	ADP
dpc-5921	141	43	ak	ak	PROPN
dpc-5921	141	44	.	.	PROPN
dpc-5921	141	45	importantly	importantly	ADV
dpc-5921	141	46	,	,	PUNCT
dpc-5921	141	47	tirbanibulin	tirbanibulin	PROPN
dpc-5921	141	48	’s	’s	PART
dpc-5921	141	49	mechanism	mechanism	NOUN
dpc-5921	141	50	of	of	ADP
dpc-5921	141	51	action	action	NOUN
dpc-5921	141	52	targets	target	NOUN
dpc-5921	141	53	oncogenic	oncogenic	ADJ
dpc-5921	141	54	pathways	pathway	NOUN
dpc-5921	141	55	that	that	PRON
dpc-5921	141	56	are	be	AUX
dpc-5921	141	57	believed	believe	VERB
dpc-5921	141	58	to	to	PART
dpc-5921	141	59	be	be	AUX
dpc-5921	141	60	key	key	ADJ
dpc-5921	141	61	factors	factor	NOUN
dpc-5921	141	62	in	in	ADP
dpc-5921	141	63	the	the	DET
dpc-5921	141	64	progression	progression	NOUN
dpc-5921	141	65	from	from	ADP
dpc-5921	141	66	ak	ak	PROPN
dpc-5921	141	67	to	to	ADP
dpc-5921	141	68	scc	scc	PROPN
dpc-5921	141	69	.	.	PUNCT
dpc-5921	142	1	the	the	DET
dpc-5921	142	2	short	short	ADJ
dpc-5921	142	3	duration	duration	NOUN
dpc-5921	142	4	of	of	ADP
dpc-5921	142	5	treatment	treatment	NOUN
dpc-5921	142	6	is	be	AUX
dpc-5921	142	7	another	another	DET
dpc-5921	142	8	aspect	aspect	NOUN
dpc-5921	142	9	of	of	ADP
dpc-5921	142	10	tirbanibulin	tirbanibulin	PROPN
dpc-5921	142	11	therapy	therapy	NOUN
dpc-5921	142	12	which	which	PRON
dpc-5921	142	13	is	be	AUX
dpc-5921	142	14	relevant	relevant	ADJ
dpc-5921	142	15	to	to	ADP
dpc-5921	142	16	real	real	ADJ
dpc-5921	142	17	-	-	PUNCT
dpc-5921	142	18	life	life	NOUN
dpc-5921	142	19	practice	practice	NOUN
dpc-5921	142	20	since	since	SCONJ
dpc-5921	142	21	,	,	PUNCT
dpc-5921	142	22	together	together	ADV
dpc-5921	142	23	with	with	ADP
dpc-5921	142	24	its	its	PRON
dpc-5921	142	25	favorable	favorable	ADJ
dpc-5921	142	26	tolerability	tolerability	NOUN
dpc-5921	142	27	profile	profile	NOUN
dpc-5921	142	28	,	,	PUNCT
dpc-5921	142	29	it	it	PRON
dpc-5921	142	30	facilitates	facilitate	VERB
dpc-5921	142	31	patient	patient	ADJ
dpc-5921	142	32	compliance	compliance	NOUN
dpc-5921	142	33	,	,	PUNCT
dpc-5921	142	34	thus	thus	ADV
dpc-5921	142	35	enhancing	enhance	VERB
dpc-5921	142	36	the	the	DET
dpc-5921	142	37	chance	chance	NOUN
dpc-5921	142	38	of	of	ADP
dpc-5921	142	39	a	a	DET
dpc-5921	142	40	successful	successful	ADJ
dpc-5921	142	41	outcome	outcome	NOUN
dpc-5921	142	42	.	.	PUNCT
dpc-5921	143	1	acceptance	acceptance	NOUN
dpc-5921	143	2	of	of	ADP
dpc-5921	143	3	therapy	therapy	NOUN
dpc-5921	143	4	and	and	CCONJ
dpc-5921	143	5	treatment	treatment	NOUN
dpc-5921	143	6	adherence	adherence	NOUN
dpc-5921	143	7	are	be	AUX
dpc-5921	143	8	important	important	ADJ
dpc-5921	143	9	considerations	consideration	NOUN
dpc-5921	143	10	in	in	ADP
dpc-5921	143	11	real	real	ADJ
dpc-5921	143	12	-	-	PUNCT
dpc-5921	143	13	world	world	NOUN
dpc-5921	143	14	practice	practice	NOUN
dpc-5921	143	15	and	and	CCONJ
dpc-5921	143	16	are	be	AUX
dpc-5921	143	17	often	often	ADV
dpc-5921	143	18	underestimated	underestimate	VERB
dpc-5921	143	19	when	when	SCONJ
dpc-5921	143	20	selecting	select	VERB
dpc-5921	143	21	ak	ak	PROPN
dpc-5921	143	22	therapies	therapy	NOUN
dpc-5921	143	23	based	base	VERB
dpc-5921	143	24	on	on	ADP
dpc-5921	143	25	evidence	evidence	NOUN
dpc-5921	143	26	derived	derive	VERB
dpc-5921	143	27	solely	solely	ADV
dpc-5921	143	28	from	from	ADP
dpc-5921	143	29	clinical	clinical	ADJ
dpc-5921	143	30	trials	trial	NOUN
dpc-5921	143	31	[	[	X
dpc-5921	143	32	36	36	NUM
dpc-5921	143	33	]	]	PUNCT
dpc-5921	143	34	.	.	PUNCT
dpc-5921	144	1	in	in	ADP
dpc-5921	144	2	a	a	DET
dpc-5921	144	3	systematic	systematic	ADJ
dpc-5921	144	4	review	review	NOUN
dpc-5921	144	5	investigating	investigate	VERB
dpc-5921	144	6	adherence	adherence	NOUN
dpc-5921	144	7	and	and	CCONJ
dpc-5921	144	8	persistence	persistence	NOUN
dpc-5921	144	9	associated	associate	VERB
dpc-5921	144	10	with	with	ADP
dpc-5921	144	11	topical	topical	ADJ
dpc-5921	144	12	ak	ak	PROPN
dpc-5921	144	13	therapies	therapy	NOUN
dpc-5921	144	14	,	,	PUNCT
dpc-5921	144	15	combined	combined	ADJ
dpc-5921	144	16	non	non	ADJ
dpc-5921	144	17	-	-	NOUN
dpc-5921	144	18	adherence	adherence	ADJ
dpc-5921	144	19	and	and	CCONJ
dpc-5921	144	20	non	non	ADJ
dpc-5921	144	21	-	-	ADJ
dpc-5921	144	22	persistence	persistence	ADJ
dpc-5921	144	23	rates	rate	NOUN
dpc-5921	144	24	were	be	AUX
dpc-5921	144	25	found	find	VERB
dpc-5921	144	26	to	to	PART
dpc-5921	144	27	be	be	AUX
dpc-5921	144	28	as	as	ADV
dpc-5921	144	29	high	high	ADJ
dpc-5921	144	30	as	as	ADP
dpc-5921	144	31	88	88	NUM
dpc-5921	144	32	%	%	NOUN
dpc-5921	144	33	,	,	PUNCT
dpc-5921	144	34	and	and	CCONJ
dpc-5921	144	35	key	key	ADJ
dpc-5921	144	36	contributing	contributing	NOUN
dpc-5921	144	37	factors	factor	NOUN
dpc-5921	144	38	were	be	AUX
dpc-5921	144	39	identified	identify	VERB
dpc-5921	144	40	as	as	ADP
dpc-5921	144	41	duration	duration	NOUN
dpc-5921	144	42	of	of	ADP
dpc-5921	144	43	treatment	treatment	NOUN
dpc-5921	144	44	,	,	PUNCT
dpc-5921	144	45	severity	severity	NOUN
dpc-5921	144	46	and	and	CCONJ
dpc-5921	144	47	persistence	persistence	NOUN
dpc-5921	144	48	of	of	ADP
dpc-5921	144	49	local	local	ADJ
dpc-5921	144	50	review	review	NOUN
dpc-5921	144	51	|	|	ADV
dpc-5921	144	52	dermatol	dermatol	ADJ
dpc-5921	144	53	pract	pract	NOUN
dpc-5921	144	54	concept	concept	NOUN
dpc-5921	144	55	.	.	PUNCT
dpc-5921	145	1	2025;15(3):5921	2025;15(3):5921	NUM
dpc-5921	145	2	7	7	NUM
dpc-5921	145	3	figure	figure	NOUN
dpc-5921	145	4	2	2	NUM
dpc-5921	145	5	.	.	NUM
dpc-5921	145	6	images	image	NOUN
dpc-5921	145	7	of	of	ADP
dpc-5921	145	8	ak	ak	PROPN
dpc-5921	145	9	lesions	lesion	NOUN
dpc-5921	145	10	(	(	PUNCT
dpc-5921	145	11	olsen	olsen	NOUN
dpc-5921	145	12	grade	grade	NOUN
dpc-5921	145	13	i	i	PROPN
dpc-5921	145	14	-	-	PUNCT
dpc-5921	145	15	ii	ii	NOUN
dpc-5921	145	16	)	)	PUNCT
dpc-5921	145	17	in	in	ADP
dpc-5921	145	18	two	two	NUM
dpc-5921	145	19	small	small	ADJ
dpc-5921	145	20	fields	field	NOUN
dpc-5921	145	21	of	of	ADP
dpc-5921	145	22	cancerization	cancerization	NOUN
dpc-5921	145	23	on	on	ADP
dpc-5921	145	24	the	the	DET
dpc-5921	145	25	scalp	scalp	NOUN
dpc-5921	145	26	of	of	ADP
dpc-5921	145	27	a	a	DET
dpc-5921	145	28	75	75	NUM
dpc-5921	145	29	-	-	PUNCT
dpc-5921	145	30	year	year	NOUN
dpc-5921	145	31	-	-	PUNCT
dpc-5921	145	32	old	old	ADJ
dpc-5921	145	33	male	male	NOUN
dpc-5921	145	34	with	with	ADP
dpc-5921	145	35	a	a	DET
dpc-5921	145	36	long	long	ADV
dpc-5921	145	37	-	-	PUNCT
dpc-5921	145	38	standing	stand	VERB
dpc-5921	145	39	history	history	NOUN
dpc-5921	145	40	(	(	PUNCT
dpc-5921	145	41	>	>	SYM
dpc-5921	145	42	5	5	NUM
dpc-5921	145	43	years	year	NOUN
dpc-5921	145	44	)	)	PUNCT
dpc-5921	145	45	of	of	ADP
dpc-5921	145	46	ak	ak	PROPN
dpc-5921	145	47	on	on	ADP
dpc-5921	145	48	the	the	DET
dpc-5921	145	49	scalp	scalp	NOUN
dpc-5921	145	50	,	,	PUNCT
dpc-5921	145	51	previously	previously	ADV
dpc-5921	145	52	treated	treat	VERB
dpc-5921	145	53	with	with	ADP
dpc-5921	145	54	cryotherapy	cryotherapy	NOUN
dpc-5921	145	55	,	,	PUNCT
dpc-5921	145	56	topical	topical	ADJ
dpc-5921	145	57	diclofenac	diclofenac	NOUN
dpc-5921	145	58	gel	gel	NOUN
dpc-5921	145	59	,	,	PUNCT
dpc-5921	145	60	and	and	CCONJ
dpc-5921	145	61	daylight	daylight	VERB
dpc-5921	145	62	photodynamic	photodynamic	ADJ
dpc-5921	145	63	therapy	therapy	NOUN
dpc-5921	145	64	:	:	PUNCT
dpc-5921	145	65	(	(	PUNCT
dpc-5921	145	66	a	a	X
dpc-5921	145	67	)	)	PUNCT
dpc-5921	145	68	before	before	ADP
dpc-5921	145	69	tirbanibulin	tirbanibulin	PROPN
dpc-5921	145	70	treatment	treatment	NOUN
dpc-5921	145	71	;	;	PUNCT
dpc-5921	145	72	(	(	PUNCT
dpc-5921	145	73	b	b	X
dpc-5921	145	74	)	)	PUNCT
dpc-5921	145	75	at	at	ADP
dpc-5921	145	76	the	the	DET
dpc-5921	145	77	2	2	NUM
dpc-5921	145	78	-	-	PUNCT
dpc-5921	145	79	month	month	NOUN
dpc-5921	145	80	follow	follow	NOUN
dpc-5921	145	81	-	-	PUNCT
dpc-5921	145	82	up	up	NOUN
dpc-5921	145	83	after	after	ADP
dpc-5921	145	84	treatment	treatment	NOUN
dpc-5921	145	85	with	with	ADP
dpc-5921	145	86	tirbanibulin	tirbanibulin	PROPN
dpc-5921	145	87	1	1	NUM
dpc-5921	145	88	%	%	NOUN
dpc-5921	145	89	ointment	ointment	NOUN
dpc-5921	145	90	,	,	PUNCT
dpc-5921	145	91	showing	show	VERB
dpc-5921	145	92	complete	complete	ADJ
dpc-5921	145	93	clearance	clearance	NOUN
dpc-5921	145	94	of	of	ADP
dpc-5921	145	95	occipital	occipital	ADJ
dpc-5921	145	96	area	area	NOUN
dpc-5921	145	97	and	and	CCONJ
dpc-5921	145	98	residual	residual	ADJ
dpc-5921	145	99	ak	ak	PROPN
dpc-5921	145	100	lesions	lesion	NOUN
dpc-5921	145	101	(	(	PUNCT
dpc-5921	145	102	olsen	olsen	NOUN
dpc-5921	145	103	grade	grade	NOUN
dpc-5921	145	104	i	i	PROPN
dpc-5921	145	105	)	)	PUNCT
dpc-5921	145	106	in	in	ADP
dpc-5921	145	107	the	the	DET
dpc-5921	145	108	parietal	parietal	ADJ
dpc-5921	145	109	field	field	NOUN
dpc-5921	145	110	.	.	PUNCT
dpc-5921	146	1	the	the	DET
dpc-5921	146	2	total	total	ADJ
dpc-5921	146	3	area	area	NOUN
dpc-5921	146	4	covered	cover	VERB
dpc-5921	146	5	by	by	ADP
dpc-5921	146	6	tirbanibulin	tirbanibulin	PROPN
dpc-5921	146	7	measured	measure	VERB
dpc-5921	146	8	26	26	NUM
dpc-5921	146	9	cm2	cm2	NOUN
dpc-5921	146	10	(	(	PUNCT
dpc-5921	146	11	2x3	2x3	NUM
dpc-5921	146	12	cm=6	cm=6	NUM
dpc-5921	146	13	cm2	cm2	PROPN
dpc-5921	146	14	for	for	ADP
dpc-5921	146	15	the	the	DET
dpc-5921	146	16	occipital	occipital	ADJ
dpc-5921	146	17	area	area	NOUN
dpc-5921	146	18	and	and	CCONJ
dpc-5921	146	19	4x5	4x5	NUM
dpc-5921	146	20	cm=20	cm=20	NOUN
dpc-5921	146	21	cm2	cm2	PROPN
dpc-5921	146	22	for	for	ADP
dpc-5921	146	23	the	the	DET
dpc-5921	146	24	parietal	parietal	ADJ
dpc-5921	146	25	area	area	NOUN
dpc-5921	146	26	)	)	PUNCT
dpc-5921	146	27	.	.	PUNCT
dpc-5921	147	1	(	(	PUNCT
dpc-5921	147	2	courtesy	courtesy	NOUN
dpc-5921	147	3	of	of	ADP
dpc-5921	147	4	dr	dr	PROPN
dpc-5921	147	5	.	.	PROPN
dpc-5921	147	6	g.	g.	PROPN
dpc-5921	147	7	nazzaro	nazzaro	PROPN
dpc-5921	147	8	)	)	PUNCT
dpc-5921	147	9	figure	figure	NOUN
dpc-5921	147	10	3	3	NUM
dpc-5921	147	11	.	.	NOUN
dpc-5921	147	12	images	image	NOUN
dpc-5921	147	13	of	of	ADP
dpc-5921	147	14	ak	ak	PROPN
dpc-5921	147	15	lesions	lesion	NOUN
dpc-5921	147	16	(	(	PUNCT
dpc-5921	147	17	olsen	olsen	NOUN
dpc-5921	147	18	grade	grade	NOUN
dpc-5921	147	19	i	i	PROPN
dpc-5921	147	20	-	-	PUNCT
dpc-5921	147	21	ii	ii	NOUN
dpc-5921	147	22	)	)	PUNCT
dpc-5921	147	23	in	in	ADP
dpc-5921	147	24	a	a	DET
dpc-5921	147	25	large	large	ADJ
dpc-5921	147	26	field	field	NOUN
dpc-5921	147	27	of	of	ADP
dpc-5921	147	28	cancerization	cancerization	NOUN
dpc-5921	147	29	on	on	ADP
dpc-5921	147	30	the	the	DET
dpc-5921	147	31	left	left	ADJ
dpc-5921	147	32	cheek	cheek	NOUN
dpc-5921	147	33	of	of	ADP
dpc-5921	147	34	a	a	DET
dpc-5921	147	35	76	76	NUM
dpc-5921	147	36	-	-	PUNCT
dpc-5921	147	37	year	year	NOUN
dpc-5921	147	38	-	-	PUNCT
dpc-5921	147	39	old	old	ADJ
dpc-5921	147	40	male	male	NOUN
dpc-5921	147	41	with	with	ADP
dpc-5921	147	42	a	a	DET
dpc-5921	147	43	history	history	NOUN
dpc-5921	147	44	of	of	ADP
dpc-5921	147	45	basal	basal	ADJ
dpc-5921	147	46	cell	cell	NOUN
dpc-5921	147	47	carcinomas	carcinoma	NOUN
dpc-5921	147	48	on	on	ADP
dpc-5921	147	49	the	the	DET
dpc-5921	147	50	trunk	trunk	NOUN
dpc-5921	147	51	and	and	CCONJ
dpc-5921	147	52	limbs	limb	NOUN
dpc-5921	147	53	and	and	CCONJ
dpc-5921	147	54	with	with	ADP
dpc-5921	147	55	ak	ak	PROPN
dpc-5921	147	56	of	of	ADP
dpc-5921	147	57	the	the	DET
dpc-5921	147	58	face	face	NOUN
dpc-5921	147	59	and	and	CCONJ
dpc-5921	147	60	scalp	scalp	NOUN
dpc-5921	147	61	(	(	PUNCT
dpc-5921	147	62	previously	previously	ADV
dpc-5921	147	63	treated	treat	VERB
dpc-5921	147	64	with	with	ADP
dpc-5921	147	65	physical	physical	ADJ
dpc-5921	147	66	therapies	therapy	NOUN
dpc-5921	147	67	and	and	CCONJ
dpc-5921	147	68	topical	topical	ADJ
dpc-5921	147	69	drugs	drug	NOUN
dpc-5921	147	70	,	,	PUNCT
dpc-5921	147	71	with	with	ADP
dpc-5921	147	72	partial	partial	ADJ
dpc-5921	147	73	results	result	NOUN
dpc-5921	147	74	):	):	PUNCT
dpc-5921	147	75	(	(	PUNCT
dpc-5921	147	76	a	a	X
dpc-5921	147	77	)	)	PUNCT
dpc-5921	147	78	before	before	ADP
dpc-5921	147	79	tirbanibulin	tirbanibulin	PROPN
dpc-5921	147	80	treatment	treatment	NOUN
dpc-5921	147	81	;	;	PUNCT
dpc-5921	147	82	(	(	PUNCT
dpc-5921	147	83	b	b	X
dpc-5921	147	84	)	)	PUNCT
dpc-5921	147	85	at	at	ADP
dpc-5921	147	86	10	10	NUM
dpc-5921	147	87	days	day	NOUN
dpc-5921	147	88	after	after	ADP
dpc-5921	147	89	the	the	DET
dpc-5921	147	90	end	end	NOUN
dpc-5921	147	91	of	of	ADP
dpc-5921	147	92	treatment	treatment	NOUN
dpc-5921	147	93	with	with	ADP
dpc-5921	147	94	tirbanibulin	tirbanibulin	PROPN
dpc-5921	147	95	1	1	NUM
dpc-5921	147	96	%	%	NOUN
dpc-5921	147	97	ointment	ointment	NOUN
dpc-5921	147	98	,	,	PUNCT
dpc-5921	147	99	showing	show	VERB
dpc-5921	147	100	erythema	erythema	ADV
dpc-5921	147	101	and	and	CCONJ
dpc-5921	147	102	scaling	scaling	NOUN
dpc-5921	147	103	/	/	SYM
dpc-5921	147	104	flaking	flake	VERB
dpc-5921	147	105	(	(	PUNCT
dpc-5921	147	106	the	the	DET
dpc-5921	147	107	patient	patient	NOUN
dpc-5921	147	108	reported	report	VERB
dpc-5921	147	109	a	a	DET
dpc-5921	147	110	burning	burn	VERB
dpc-5921	147	111	sensation	sensation	NOUN
dpc-5921	147	112	in	in	ADP
dpc-5921	147	113	the	the	DET
dpc-5921	147	114	application	application	NOUN
dpc-5921	147	115	area	area	NOUN
dpc-5921	147	116	,	,	PUNCT
dpc-5921	147	117	but	but	CCONJ
dpc-5921	147	118	no	no	DET
dpc-5921	147	119	intervention	intervention	NOUN
dpc-5921	147	120	was	be	AUX
dpc-5921	147	121	required	require	VERB
dpc-5921	147	122	)	)	PUNCT
dpc-5921	147	123	;	;	PUNCT
dpc-5921	147	124	(	(	PUNCT
dpc-5921	147	125	c	c	X
dpc-5921	147	126	)	)	PUNCT
dpc-5921	147	127	at	at	ADP
dpc-5921	147	128	60	60	NUM
dpc-5921	147	129	days	day	NOUN
dpc-5921	147	130	after	after	ADP
dpc-5921	147	131	the	the	DET
dpc-5921	147	132	end	end	NOUN
dpc-5921	147	133	of	of	ADP
dpc-5921	147	134	treatment	treatment	NOUN
dpc-5921	147	135	,	,	PUNCT
dpc-5921	147	136	showing	show	VERB
dpc-5921	147	137	complete	complete	ADJ
dpc-5921	147	138	clearance	clearance	NOUN
dpc-5921	147	139	of	of	ADP
dpc-5921	147	140	the	the	DET
dpc-5921	147	141	ak	ak	PROPN
dpc-5921	147	142	lesions	lesion	NOUN
dpc-5921	147	143	(	(	PUNCT
dpc-5921	147	144	both	both	DET
dpc-5921	147	145	olsen	olsen	NOUN
dpc-5921	147	146	grade	grade	NOUN
dpc-5921	147	147	i	i	PROPN
dpc-5921	147	148	and	and	CCONJ
dpc-5921	147	149	ii	ii	NOUN
dpc-5921	147	150	)	)	PUNCT
dpc-5921	147	151	and	and	CCONJ
dpc-5921	147	152	resolution	resolution	NOUN
dpc-5921	147	153	of	of	ADP
dpc-5921	147	154	the	the	DET
dpc-5921	147	155	local	local	ADJ
dpc-5921	147	156	adverse	adverse	ADJ
dpc-5921	147	157	reactions	reaction	NOUN
dpc-5921	147	158	.	.	PUNCT
dpc-5921	148	1	(	(	PUNCT
dpc-5921	148	2	courtesy	courtesy	NOUN
dpc-5921	148	3	of	of	ADP
dpc-5921	148	4	dr	dr	PROPN
dpc-5921	148	5	.	.	PROPN
dpc-5921	148	6	a.	a.	PROPN
dpc-5921	148	7	villani	villani	PROPN
dpc-5921	148	8	)	)	PUNCT
dpc-5921	148	9	benefit	benefit	NOUN
dpc-5921	148	10	of	of	ADP
dpc-5921	148	11	cosmetic	cosmetic	ADJ
dpc-5921	148	12	improvement	improvement	NOUN
dpc-5921	148	13	induced	induce	VERB
dpc-5921	148	14	by	by	ADP
dpc-5921	148	15	tirbanibulin	tirbanibulin	PROPN
dpc-5921	148	16	therapy	therapy	NOUN
dpc-5921	148	17	should	should	AUX
dpc-5921	148	18	be	be	AUX
dpc-5921	148	19	mentioned	mention	VERB
dpc-5921	148	20	to	to	ADP
dpc-5921	148	21	patients	patient	NOUN
dpc-5921	148	22	,	,	PUNCT
dpc-5921	148	23	as	as	SCONJ
dpc-5921	148	24	it	it	PRON
dpc-5921	148	25	may	may	AUX
dpc-5921	148	26	represent	represent	VERB
dpc-5921	148	27	an	an	DET
dpc-5921	148	28	additional	additional	ADJ
dpc-5921	148	29	motivation	motivation	NOUN
dpc-5921	148	30	for	for	ADP
dpc-5921	148	31	treatment	treatment	NOUN
dpc-5921	148	32	,	,	PUNCT
dpc-5921	148	33	further	far	ADV
dpc-5921	148	34	enhancing	enhance	VERB
dpc-5921	148	35	compliance	compliance	NOUN
dpc-5921	148	36	.	.	PUNCT
dpc-5921	149	1	treatment	treatment	NOUN
dpc-5921	149	2	modalities	modality	NOUN
dpc-5921	149	3	and	and	CCONJ
dpc-5921	149	4	patient	patient	ADJ
dpc-5921	149	5	education	education	NOUN
dpc-5921	149	6	the	the	DET
dpc-5921	149	7	area	area	NOUN
dpc-5921	149	8	of	of	ADP
dpc-5921	149	9	skin	skin	NOUN
dpc-5921	149	10	to	to	PART
dpc-5921	149	11	be	be	AUX
dpc-5921	149	12	treated	treat	VERB
dpc-5921	149	13	with	with	ADP
dpc-5921	149	14	tirbanibulin	tirbanibulin	PROPN
dpc-5921	149	15	ointment	ointment	NOUN
dpc-5921	149	16	depends	depend	VERB
dpc-5921	149	17	on	on	ADP
dpc-5921	149	18	the	the	DET
dpc-5921	149	19	distribution	distribution	NOUN
dpc-5921	149	20	of	of	ADP
dpc-5921	149	21	ak	ak	PROPN
dpc-5921	149	22	lesions	lesion	NOUN
dpc-5921	149	23	and	and	CCONJ
dpc-5921	149	24	fc	fc	X
dpc-5921	149	25	on	on	ADP
dpc-5921	149	26	the	the	DET
dpc-5921	149	27	face	face	NOUN
dpc-5921	149	28	and	and	CCONJ
dpc-5921	149	29	scalp	scalp	NOUN
dpc-5921	149	30	.	.	PUNCT
dpc-5921	150	1	in	in	ADP
dpc-5921	150	2	line	line	NOUN
dpc-5921	150	3	with	with	ADP
dpc-5921	150	4	current	current	ADJ
dpc-5921	150	5	indications	indication	NOUN
dpc-5921	150	6	,	,	PUNCT
dpc-5921	150	7	a	a	DET
dpc-5921	150	8	thin	thin	ADJ
dpc-5921	150	9	layer	layer	NOUN
dpc-5921	150	10	of	of	ADP
dpc-5921	150	11	tirbanibulin	tirbanibulin	DET
dpc-5921	150	12	1	1	NUM
dpc-5921	150	13	%	%	NOUN
dpc-5921	150	14	ointment	ointment	NOUN
dpc-5921	150	15	should	should	AUX
dpc-5921	150	16	be	be	AUX
dpc-5921	150	17	applied	apply	VERB
dpc-5921	150	18	to	to	PART
dpc-5921	150	19	cover	cover	VERB
dpc-5921	150	20	a	a	DET
dpc-5921	150	21	25	25	NUM
dpc-5921	150	22	cm2	cm2	NOUN
dpc-5921	150	23	treatment	treatment	NOUN
dpc-5921	150	24	field	field	NOUN
dpc-5921	150	25	in	in	ADP
dpc-5921	150	26	each	each	DET
dpc-5921	150	27	of	of	ADP
dpc-5921	150	28	four	four	NUM
dpc-5921	150	29	anatomical	anatomical	ADJ
dpc-5921	150	30	areas	area	NOUN
dpc-5921	150	31	(	(	PUNCT
dpc-5921	150	32	scalp	scalp	NOUN
dpc-5921	150	33	,	,	PUNCT
dpc-5921	150	34	forehead	forehead	NOUN
dpc-5921	150	35	,	,	PUNCT
dpc-5921	150	36	left	leave	VERB
dpc-5921	150	37	/	/	SYM
dpc-5921	150	38	right	right	ADJ
dpc-5921	150	39	cheek	cheek	NOUN
dpc-5921	150	40	with	with	ADP
dpc-5921	150	41	ear	ear	NOUN
dpc-5921	150	42	,	,	PUNCT
dpc-5921	150	43	nose	nose	NOUN
dpc-5921	150	44	,	,	PUNCT
dpc-5921	150	45	and	and	CCONJ
dpc-5921	150	46	chin	chin	NOUN
dpc-5921	150	47	)	)	PUNCT
dpc-5921	150	48	.	.	PUNCT
dpc-5921	151	1	when	when	SCONJ
dpc-5921	151	2	treatment	treatment	NOUN
dpc-5921	151	3	fields	field	NOUN
dpc-5921	151	4	are	be	AUX
dpc-5921	151	5	not	not	PART
dpc-5921	151	6	in	in	ADP
dpc-5921	151	7	close	close	ADJ
dpc-5921	151	8	proximity	proximity	NOUN
dpc-5921	151	9	,	,	PUNCT
dpc-5921	151	10	the	the	DET
dpc-5921	151	11	total	total	ADJ
dpc-5921	151	12	area	area	NOUN
dpc-5921	151	13	to	to	PART
dpc-5921	151	14	be	be	AUX
dpc-5921	151	15	covered	cover	VERB
dpc-5921	151	16	by	by	ADP
dpc-5921	151	17	tirbanibulin	tirbanibulin	PROPN
dpc-5921	151	18	can	can	AUX
dpc-5921	151	19	be	be	AUX
dpc-5921	151	20	divided	divide	VERB
dpc-5921	151	21	into	into	ADP
dpc-5921	151	22	smaller	small	ADJ
dpc-5921	151	23	sections	section	NOUN
dpc-5921	151	24	,	,	PUNCT
dpc-5921	151	25	as	as	SCONJ
dpc-5921	151	26	shown	show	VERB
dpc-5921	151	27	in	in	ADP
dpc-5921	151	28	figure	figure	NOUN
dpc-5921	151	29	2	2	NUM
dpc-5921	151	30	.	.	PUNCT
dpc-5921	151	31	addressing	address	VERB
dpc-5921	151	32	the	the	DET
dpc-5921	151	33	needs	need	NOUN
dpc-5921	151	34	of	of	ADP
dpc-5921	151	35	patients	patient	NOUN
dpc-5921	151	36	with	with	ADP
dpc-5921	151	37	large	large	ADJ
dpc-5921	151	38	ak	ak	PROPN
dpc-5921	151	39	fields	field	NOUN
dpc-5921	151	40	to	to	PART
dpc-5921	151	41	be	be	AUX
dpc-5921	151	42	treated	treat	VERB
dpc-5921	151	43	,	,	PUNCT
dpc-5921	151	44	recent	recent	ADJ
dpc-5921	151	45	studies	study	NOUN
dpc-5921	151	46	have	have	AUX
dpc-5921	151	47	evaluated	evaluate	VERB
dpc-5921	151	48	8	8	NUM
dpc-5921	151	49	review	review	NOUN
dpc-5921	151	50	|	|	ADV
dpc-5921	151	51	dermatol	dermatol	ADJ
dpc-5921	151	52	pract	pract	NOUN
dpc-5921	151	53	concept	concept	NOUN
dpc-5921	151	54	.	.	PUNCT
dpc-5921	152	1	2025;15(3):5921	2025;15(3):5921	NUM
dpc-5921	152	2	figure	figure	VERB
dpc-5921	152	3	4	4	NUM
dpc-5921	152	4	.	.	NOUN
dpc-5921	152	5	images	image	NOUN
dpc-5921	152	6	of	of	ADP
dpc-5921	152	7	multiple	multiple	ADJ
dpc-5921	152	8	ak	ak	PROPN
dpc-5921	152	9	lesions	lesion	NOUN
dpc-5921	152	10	(	(	PUNCT
dpc-5921	152	11	olsen	olsen	NOUN
dpc-5921	152	12	grade	grade	NOUN
dpc-5921	152	13	i	i	PROPN
dpc-5921	152	14	-	-	PUNCT
dpc-5921	152	15	ii	ii	NOUN
dpc-5921	152	16	)	)	PUNCT
dpc-5921	152	17	,	,	PUNCT
dpc-5921	152	18	field	field	NOUN
dpc-5921	152	19	of	of	ADP
dpc-5921	152	20	cancerization	cancerization	NOUN
dpc-5921	152	21	,	,	PUNCT
dpc-5921	152	22	and	and	CCONJ
dpc-5921	152	23	actinic	actinic	ADJ
dpc-5921	152	24	cheilitis	cheilitis	NOUN
dpc-5921	152	25	on	on	ADP
dpc-5921	152	26	the	the	DET
dpc-5921	152	27	face	face	NOUN
dpc-5921	152	28	of	of	ADP
dpc-5921	152	29	a	a	DET
dpc-5921	152	30	70	70	NUM
dpc-5921	152	31	-	-	PUNCT
dpc-5921	152	32	year	year	NOUN
dpc-5921	152	33	-	-	PUNCT
dpc-5921	152	34	old	old	ADJ
dpc-5921	152	35	treatment	treatment	NOUN
dpc-5921	152	36	-	-	PUNCT
dpc-5921	152	37	naïve	naïve	ADJ
dpc-5921	152	38	woman	woman	NOUN
dpc-5921	152	39	:	:	PUNCT
dpc-5921	152	40	a	a	X
dpc-5921	152	41	)	)	PUNCT
dpc-5921	152	42	before	before	ADP
dpc-5921	152	43	treatment	treatment	NOUN
dpc-5921	152	44	,	,	PUNCT
dpc-5921	152	45	in	in	ADP
dpc-5921	152	46	the	the	DET
dpc-5921	152	47	foreground	foreground	NOUN
dpc-5921	152	48	square	square	NOUN
dpc-5921	152	49	close	close	NOUN
dpc-5921	152	50	-	-	PUNCT
dpc-5921	152	51	up	up	NOUN
dpc-5921	152	52	;	;	PUNCT
dpc-5921	152	53	b	b	X
dpc-5921	152	54	)	)	PUNCT
dpc-5921	152	55	at	at	ADP
dpc-5921	152	56	four	four	NUM
dpc-5921	152	57	months	month	NOUN
dpc-5921	152	58	after	after	ADP
dpc-5921	152	59	completion	completion	NOUN
dpc-5921	152	60	of	of	ADP
dpc-5921	152	61	4	4	NUM
dpc-5921	152	62	cycles	cycle	NOUN
dpc-5921	152	63	of	of	ADP
dpc-5921	152	64	tirbanibulin	tirbanibulin	DET
dpc-5921	152	65	1	1	NUM
dpc-5921	152	66	%	%	NOUN
dpc-5921	152	67	ointment	ointment	NOUN
dpc-5921	152	68	(	(	PUNCT
dpc-5921	152	69	standard	standard	ADJ
dpc-5921	152	70	treatment	treatment	NOUN
dpc-5921	152	71	of	of	ADP
dpc-5921	152	72	five	five	NUM
dpc-5921	152	73	days	day	NOUN
dpc-5921	152	74	per	per	ADP
dpc-5921	152	75	cycle	cycle	NOUN
dpc-5921	152	76	)	)	PUNCT
dpc-5921	152	77	,	,	PUNCT
dpc-5921	152	78	showing	show	VERB
dpc-5921	152	79	efficacy	efficacy	NOUN
dpc-5921	152	80	on	on	ADP
dpc-5921	152	81	ak	ak	PROPN
dpc-5921	152	82	lesions	lesion	NOUN
dpc-5921	152	83	,	,	PUNCT
dpc-5921	152	84	fc	fc	X
dpc-5921	152	85	,	,	PUNCT
dpc-5921	152	86	and	and	CCONJ
dpc-5921	152	87	actinic	actinic	ADJ
dpc-5921	152	88	cheilitis	cheilitis	NOUN
dpc-5921	152	89	(	(	PUNCT
dpc-5921	152	90	with	with	ADP
dpc-5921	152	91	a	a	DET
dpc-5921	152	92	close	close	NOUN
dpc-5921	152	93	-	-	PUNCT
dpc-5921	152	94	up	up	NOUN
dpc-5921	152	95	in	in	ADP
dpc-5921	152	96	the	the	DET
dpc-5921	152	97	foreground	foreground	NOUN
dpc-5921	152	98	square	square	PROPN
dpc-5921	152	99	)	)	PUNCT
dpc-5921	152	100	as	as	ADV
dpc-5921	152	101	well	well	ADV
dpc-5921	152	102	as	as	ADP
dpc-5921	152	103	improvement	improvement	NOUN
dpc-5921	152	104	in	in	ADP
dpc-5921	152	105	skin	skin	NOUN
dpc-5921	152	106	quality	quality	NOUN
dpc-5921	152	107	,	,	PUNCT
dpc-5921	152	108	with	with	ADP
dpc-5921	152	109	reduction	reduction	NOUN
dpc-5921	152	110	in	in	ADP
dpc-5921	152	111	dyspigmentation	dyspigmentation	NOUN
dpc-5921	152	112	and	and	CCONJ
dpc-5921	152	113	a	a	DET
dpc-5921	152	114	more	more	ADV
dpc-5921	152	115	uniform	uniform	ADJ
dpc-5921	152	116	complexion	complexion	NOUN
dpc-5921	152	117	.	.	PUNCT
dpc-5921	153	1	a	a	DET
dpc-5921	153	2	sequential	sequential	ADJ
dpc-5921	153	3	treatment	treatment	NOUN
dpc-5921	153	4	scheduled	schedule	VERB
dpc-5921	153	5	was	be	AUX
dpc-5921	153	6	adopted	adopt	VERB
dpc-5921	153	7	,	,	PUNCT
dpc-5921	153	8	with	with	ADP
dpc-5921	153	9	four	four	NUM
dpc-5921	153	10	cycles	cycle	NOUN
dpc-5921	153	11	10	10	NUM
dpc-5921	153	12	to	to	PART
dpc-5921	153	13	30	30	NUM
dpc-5921	153	14	days	day	NOUN
dpc-5921	153	15	apart	apart	ADV
dpc-5921	153	16	,	,	PUNCT
dpc-5921	153	17	as	as	SCONJ
dpc-5921	153	18	follows	follow	VERB
dpc-5921	153	19	:	:	PUNCT
dpc-5921	153	20	cycle	cycle	NOUN
dpc-5921	153	21	1→right	1→right	NUM
dpc-5921	153	22	forehead	forehead	NOUN
dpc-5921	153	23	and	and	CCONJ
dpc-5921	153	24	nose	nose	NOUN
dpc-5921	153	25	,	,	PUNCT
dpc-5921	153	26	cycle	cycle	NOUN
dpc-5921	153	27	2→left	2→left	NUM
dpc-5921	153	28	forehead	forehead	NOUN
dpc-5921	153	29	and	and	CCONJ
dpc-5921	153	30	nose	nose	NOUN
dpc-5921	153	31	,	,	PUNCT
dpc-5921	153	32	cycle	cycle	NOUN
dpc-5921	153	33	3→right	3→right	NUM
dpc-5921	153	34	cheek	cheek	NOUN
dpc-5921	153	35	,	,	PUNCT
dpc-5921	153	36	cycle	cycle	NOUN
dpc-5921	153	37	4→left	4→left	NUM
dpc-5921	153	38	cheek	cheek	NOUN
dpc-5921	153	39	.	.	PUNCT
dpc-5921	154	1	(	(	PUNCT
dpc-5921	154	2	courtesy	courtesy	NOUN
dpc-5921	154	3	of	of	ADP
dpc-5921	154	4	dr	dr	PROPN
dpc-5921	154	5	.	.	PROPN
dpc-5921	154	6	s.	s.	PROPN
dpc-5921	154	7	guida	guida	PROPN
dpc-5921	154	8	)	)	PUNCT
dpc-5921	154	9	figure	figure	NOUN
dpc-5921	154	10	5	5	NUM
dpc-5921	154	11	.	.	PUNCT
dpc-5921	154	12	images	image	NOUN
dpc-5921	154	13	(	(	PUNCT
dpc-5921	154	14	with	with	ADP
dpc-5921	154	15	dermatoscopic	dermatoscopic	ADJ
dpc-5921	154	16	view	view	NOUN
dpc-5921	154	17	)	)	PUNCT
dpc-5921	154	18	of	of	ADP
dpc-5921	154	19	ak	ak	PROPN
dpc-5921	154	20	lesions	lesion	NOUN
dpc-5921	154	21	(	(	PUNCT
dpc-5921	154	22	olsen	olsen	NOUN
dpc-5921	154	23	grade	grade	NOUN
dpc-5921	154	24	i	i	PROPN
dpc-5921	154	25	-	-	PUNCT
dpc-5921	154	26	ii	ii	NOUN
dpc-5921	154	27	)	)	PUNCT
dpc-5921	154	28	in	in	ADP
dpc-5921	154	29	the	the	DET
dpc-5921	154	30	right	right	ADJ
dpc-5921	154	31	frontotemporal	frontotemporal	ADJ
dpc-5921	154	32	region	region	NOUN
dpc-5921	154	33	of	of	ADP
dpc-5921	154	34	an	an	DET
dpc-5921	154	35	83	83	NUM
dpc-5921	154	36	-	-	PUNCT
dpc-5921	154	37	year	year	NOUN
dpc-5921	154	38	-	-	PUNCT
dpc-5921	154	39	old	old	ADJ
dpc-5921	154	40	male	male	NOUN
dpc-5921	154	41	,	,	PUNCT
dpc-5921	154	42	fitzpatrick	fitzpatrick	PROPN
dpc-5921	154	43	skin	skin	PROPN
dpc-5921	154	44	type	type	NOUN
dpc-5921	155	1	i	i	PRON
dpc-5921	155	2	,	,	PUNCT
dpc-5921	155	3	with	with	ADP
dpc-5921	155	4	a	a	DET
dpc-5921	155	5	history	history	NOUN
dpc-5921	155	6	of	of	ADP
dpc-5921	155	7	chronic	chronic	ADJ
dpc-5921	155	8	sun	sun	NOUN
dpc-5921	155	9	exposure	exposure	NOUN
dpc-5921	155	10	and	and	CCONJ
dpc-5921	155	11	an	an	DET
dpc-5921	155	12	extensive	extensive	ADJ
dpc-5921	155	13	field	field	NOUN
dpc-5921	155	14	of	of	ADP
dpc-5921	155	15	cancerization	cancerization	NOUN
dpc-5921	155	16	involving	involve	VERB
dpc-5921	155	17	the	the	DET
dpc-5921	155	18	head	head	NOUN
dpc-5921	155	19	and	and	CCONJ
dpc-5921	155	20	neck	neck	NOUN
dpc-5921	155	21	which	which	PRON
dpc-5921	155	22	was	be	AUX
dpc-5921	155	23	treated	treat	VERB
dpc-5921	155	24	with	with	ADP
dpc-5921	155	25	cycles	cycle	NOUN
dpc-5921	155	26	of	of	ADP
dpc-5921	155	27	oral	oral	ADJ
dpc-5921	155	28	nicotinamide	nicotinamide	NOUN
dpc-5921	155	29	250	250	NUM
dpc-5921	155	30	mg	mg	NUM
dpc-5921	155	31	four	four	NUM
dpc-5921	155	32	times	time	NOUN
dpc-5921	155	33	daily	daily	ADV
dpc-5921	155	34	.	.	PUNCT
dpc-5921	156	1	ak	ak	PROPN
dpc-5921	156	2	lesions	lesion	NOUN
dpc-5921	156	3	had	have	AUX
dpc-5921	156	4	previously	previously	ADV
dpc-5921	156	5	been	be	AUX
dpc-5921	156	6	treated	treat	VERB
dpc-5921	156	7	with	with	ADP
dpc-5921	156	8	imiquimod	imiquimod	ADJ
dpc-5921	156	9	5	5	NUM
dpc-5921	156	10	%	%	NOUN
dpc-5921	156	11	and	and	CCONJ
dpc-5921	156	12	piroxicam	piroxicam	VERB
dpc-5921	156	13	and	and	CCONJ
dpc-5921	156	14	sun	sun	NOUN
dpc-5921	156	15	filters	filter	NOUN
dpc-5921	156	16	for	for	ADP
dpc-5921	156	17	local	local	ADJ
dpc-5921	156	18	use	use	NOUN
dpc-5921	156	19	.	.	PUNCT
dpc-5921	157	1	the	the	DET
dpc-5921	157	2	patient	patient	NOUN
dpc-5921	157	3	also	also	ADV
dpc-5921	157	4	had	have	VERB
dpc-5921	157	5	comorbid	comorbid	NOUN
dpc-5921	157	6	ischemic	ischemic	ADJ
dpc-5921	157	7	heart	heart	NOUN
dpc-5921	157	8	disease	disease	NOUN
dpc-5921	157	9	and	and	CCONJ
dpc-5921	157	10	depression	depression	NOUN
dpc-5921	157	11	(	(	PUNCT
dpc-5921	157	12	treated	treat	VERB
dpc-5921	157	13	with	with	ADP
dpc-5921	157	14	calcium	calcium	NOUN
dpc-5921	157	15	antagonists	antagonist	NOUN
dpc-5921	157	16	,	,	PUNCT
dpc-5921	157	17	clopidogrel	clopidogrel	NOUN
dpc-5921	157	18	,	,	PUNCT
dpc-5921	157	19	and	and	CCONJ
dpc-5921	157	20	sertraline	sertraline	NOUN
dpc-5921	157	21	)	)	PUNCT
dpc-5921	157	22	and	and	CCONJ
dpc-5921	157	23	had	have	AUX
dpc-5921	157	24	undergone	undergo	VERB
dpc-5921	157	25	surgery	surgery	NOUN
dpc-5921	157	26	for	for	ADP
dpc-5921	157	27	a	a	DET
dpc-5921	157	28	pigmented	pigment	VERB
dpc-5921	157	29	basal	basal	NOUN
dpc-5921	157	30	cell	cell	NOUN
dpc-5921	157	31	carcinoma	carcinoma	NOUN
dpc-5921	157	32	on	on	ADP
dpc-5921	157	33	the	the	DET
dpc-5921	157	34	forehead	forehead	NOUN
dpc-5921	157	35	.	.	PUNCT
dpc-5921	158	1	(	(	PUNCT
dpc-5921	158	2	a	a	X
dpc-5921	158	3	)	)	PUNCT
dpc-5921	158	4	before	before	ADP
dpc-5921	158	5	tirbanibulin	tirbanibulin	PROPN
dpc-5921	158	6	treatment	treatment	NOUN
dpc-5921	158	7	;	;	PUNCT
dpc-5921	158	8	(	(	PUNCT
dpc-5921	158	9	b	b	X
dpc-5921	158	10	)	)	PUNCT
dpc-5921	158	11	at	at	ADP
dpc-5921	158	12	12	12	NUM
dpc-5921	158	13	days	day	NOUN
dpc-5921	158	14	after	after	ADP
dpc-5921	158	15	starting	start	VERB
dpc-5921	158	16	treatment	treatment	NOUN
dpc-5921	158	17	with	with	ADP
dpc-5921	158	18	tirbanibulin	tirbanibulin	PROPN
dpc-5921	158	19	1	1	NUM
dpc-5921	158	20	%	%	NOUN
dpc-5921	158	21	ointment	ointment	NOUN
dpc-5921	158	22	,	,	PUNCT
dpc-5921	158	23	showing	show	VERB
dpc-5921	158	24	mild	mild	ADJ
dpc-5921	158	25	,	,	PUNCT
dpc-5921	158	26	well	well	ADV
dpc-5921	158	27	-	-	PUNCT
dpc-5921	158	28	tolerated	tolerate	VERB
dpc-5921	158	29	local	local	ADJ
dpc-5921	158	30	reactions	reaction	NOUN
dpc-5921	158	31	(	(	PUNCT
dpc-5921	158	32	erythema	erythema	ADV
dpc-5921	158	33	and	and	CCONJ
dpc-5921	158	34	flaking	flake	VERB
dpc-5921	158	35	)	)	PUNCT
dpc-5921	158	36	;	;	PUNCT
dpc-5921	158	37	(	(	PUNCT
dpc-5921	158	38	c	c	X
dpc-5921	158	39	)	)	PUNCT
dpc-5921	158	40	at	at	ADP
dpc-5921	158	41	58	58	NUM
dpc-5921	158	42	days	day	NOUN
dpc-5921	158	43	after	after	ADP
dpc-5921	158	44	treatment	treatment	NOUN
dpc-5921	158	45	,	,	PUNCT
dpc-5921	158	46	showing	show	VERB
dpc-5921	158	47	complete	complete	ADJ
dpc-5921	158	48	clearance	clearance	NOUN
dpc-5921	158	49	of	of	ADP
dpc-5921	158	50	the	the	DET
dpc-5921	158	51	ak	ak	PROPN
dpc-5921	158	52	lesion	lesion	NOUN
dpc-5921	158	53	.	.	PUNCT
dpc-5921	159	1	(	(	PUNCT
dpc-5921	159	2	courtesy	courtesy	NOUN
dpc-5921	159	3	of	of	ADP
dpc-5921	159	4	prof	prof	PROPN
dpc-5921	159	5	.	.	PUNCT
dpc-5921	160	1	e.	e.	PROPN
dpc-5921	160	2	campione	campione	PROPN
dpc-5921	160	3	)	)	PUNCT
dpc-5921	160	4	review	review	NOUN
dpc-5921	160	5	|	|	ADV
dpc-5921	160	6	dermatol	dermatol	ADJ
dpc-5921	160	7	pract	pract	NOUN
dpc-5921	160	8	concept	concept	NOUN
dpc-5921	160	9	.	.	PUNCT
dpc-5921	161	1	2025;15(3):5921	2025;15(3):5921	NUM
dpc-5921	161	2	9	9	NUM
dpc-5921	161	3	favorable	favorable	ADJ
dpc-5921	161	4	tolerability	tolerability	NOUN
dpc-5921	161	5	profile	profile	NOUN
dpc-5921	161	6	of	of	ADP
dpc-5921	161	7	this	this	DET
dpc-5921	161	8	topical	topical	ADJ
dpc-5921	161	9	drug	drug	NOUN
dpc-5921	161	10	.	.	PUNCT
dpc-5921	162	1	in	in	ADP
dpc-5921	162	2	clinical	clinical	ADJ
dpc-5921	162	3	studies	study	NOUN
dpc-5921	162	4	as	as	ADV
dpc-5921	162	5	well	well	ADV
dpc-5921	162	6	as	as	ADP
dpc-5921	162	7	in	in	ADP
dpc-5921	162	8	routine	routine	ADJ
dpc-5921	162	9	clinical	clinical	ADJ
dpc-5921	162	10	practice	practice	NOUN
dpc-5921	162	11	,	,	PUNCT
dpc-5921	162	12	tirbanibulin	tirbanibulin	PRON
dpc-5921	162	13	therapy	therapy	NOUN
dpc-5921	162	14	is	be	AUX
dpc-5921	162	15	associated	associate	VERB
dpc-5921	162	16	with	with	ADP
dpc-5921	162	17	high	high	ADJ
dpc-5921	162	18	rates	rate	NOUN
dpc-5921	162	19	of	of	ADP
dpc-5921	162	20	patient	patient	ADJ
dpc-5921	162	21	acceptability	acceptability	NOUN
dpc-5921	162	22	and	and	CCONJ
dpc-5921	162	23	treatment	treatment	NOUN
dpc-5921	162	24	compliance	compliance	NOUN
dpc-5921	162	25	,	,	PUNCT
dpc-5921	162	26	thus	thus	ADV
dpc-5921	162	27	increasing	increase	VERB
dpc-5921	162	28	the	the	DET
dpc-5921	162	29	chance	chance	NOUN
dpc-5921	162	30	of	of	ADP
dpc-5921	162	31	a	a	DET
dpc-5921	162	32	successful	successful	ADJ
dpc-5921	162	33	outcome	outcome	NOUN
dpc-5921	162	34	.	.	PUNCT
dpc-5921	163	1	references	reference	NOUN
dpc-5921	163	2	1	1	NUM
dpc-5921	163	3	.	.	PUNCT
dpc-5921	163	4	kandolf	kandolf	PROPN
dpc-5921	163	5	l	l	PROPN
dpc-5921	163	6	,	,	PUNCT
dpc-5921	163	7	peris	peris	PROPN
dpc-5921	163	8	k	k	PROPN
dpc-5921	163	9	,	,	PUNCT
dpc-5921	163	10	malvehy	malvehy	PROPN
dpc-5921	163	11	j	j	PROPN
dpc-5921	163	12	,	,	PUNCT
dpc-5921	163	13	et	et	PROPN
dpc-5921	163	14	al	al	PROPN
dpc-5921	163	15	.	.	PROPN
dpc-5921	163	16	european	european	PROPN
dpc-5921	163	17	association	association	PROPN
dpc-5921	163	18	of	of	ADP
dpc-5921	163	19	dermato	dermato	PROPN
dpc-5921	163	20	-	-	PUNCT
dpc-5921	163	21	oncology	oncology	NOUN
dpc-5921	163	22	,	,	PUNCT
dpc-5921	163	23	european	european	ADJ
dpc-5921	163	24	dermatology	dermatology	PROPN
dpc-5921	163	25	forum	forum	PROPN
dpc-5921	163	26	,	,	PUNCT
dpc-5921	163	27	european	european	PROPN
dpc-5921	163	28	academy	academy	PROPN
dpc-5921	163	29	of	of	ADP
dpc-5921	163	30	dermatology	dermatology	NOUN
dpc-5921	163	31	and	and	CCONJ
dpc-5921	163	32	venereology	venereology	NOUN
dpc-5921	163	33	and	and	CCONJ
dpc-5921	163	34	union	union	NOUN
dpc-5921	163	35	of	of	ADP
dpc-5921	163	36	medical	medical	ADJ
dpc-5921	163	37	specialists	specialist	NOUN
dpc-5921	163	38	(	(	PUNCT
dpc-5921	163	39	union	union	PROPN
dpc-5921	163	40	européenne	européenne	PROPN
dpc-5921	163	41	des	des	PROPN
dpc-5921	163	42	médecins	médecins	PROPN
dpc-5921	163	43	spécialistes	spécialiste	NOUN
dpc-5921	163	44	)	)	PUNCT
dpc-5921	163	45	.	.	PUNCT
dpc-5921	164	1	european	european	ADJ
dpc-5921	164	2	consensus	consensus	NOUN
dpc-5921	164	3	-	-	PUNCT
dpc-5921	164	4	based	base	VERB
dpc-5921	164	5	interdisciplinary	interdisciplinary	ADJ
dpc-5921	164	6	guideline	guideline	NOUN
dpc-5921	164	7	for	for	ADP
dpc-5921	164	8	diagnosis	diagnosis	NOUN
dpc-5921	164	9	,	,	PUNCT
dpc-5921	164	10	treatment	treatment	NOUN
dpc-5921	164	11	and	and	CCONJ
dpc-5921	164	12	prevention	prevention	NOUN
dpc-5921	164	13	of	of	ADP
dpc-5921	164	14	actinic	actinic	ADJ
dpc-5921	164	15	keratoses	keratose	NOUN
dpc-5921	164	16	,	,	PUNCT
dpc-5921	164	17	epithelial	epithelial	ADJ
dpc-5921	164	18	uv	uv	NOUN
dpc-5921	164	19	-	-	PUNCT
dpc-5921	164	20	induced	induce	VERB
dpc-5921	164	21	dysplasia	dysplasia	NOUN
dpc-5921	164	22	and	and	CCONJ
dpc-5921	164	23	field	field	NOUN
dpc-5921	164	24	cancerization	cancerization	NOUN
dpc-5921	164	25	on	on	ADP
dpc-5921	164	26	behalf	behalf	NOUN
dpc-5921	164	27	of	of	ADP
dpc-5921	164	28	european	european	PROPN
dpc-5921	164	29	association	association	PROPN
dpc-5921	164	30	of	of	ADP
dpc-5921	164	31	dermato	dermato	PROPN
dpc-5921	164	32	-	-	PUNCT
dpc-5921	164	33	oncology	oncology	NOUN
dpc-5921	164	34	,	,	PUNCT
dpc-5921	164	35	european	european	ADJ
dpc-5921	164	36	dermatology	dermatology	PROPN
dpc-5921	164	37	forum	forum	PROPN
dpc-5921	164	38	,	,	PUNCT
dpc-5921	164	39	european	european	PROPN
dpc-5921	164	40	academy	academy	PROPN
dpc-5921	164	41	of	of	ADP
dpc-5921	164	42	dermatology	dermatology	NOUN
dpc-5921	164	43	and	and	CCONJ
dpc-5921	164	44	venereology	venereology	NOUN
dpc-5921	164	45	and	and	CCONJ
dpc-5921	164	46	union	union	NOUN
dpc-5921	164	47	of	of	ADP
dpc-5921	164	48	medical	medical	ADJ
dpc-5921	164	49	specialists	specialist	NOUN
dpc-5921	164	50	(	(	PUNCT
dpc-5921	164	51	union	union	PROPN
dpc-5921	164	52	européenne	européenne	PROPN
dpc-5921	164	53	des	des	PROPN
dpc-5921	164	54	médecins	médecins	PROPN
dpc-5921	164	55	spécialistes	spécialiste	NOUN
dpc-5921	164	56	)	)	PUNCT
dpc-5921	164	57	.	.	PUNCT
dpc-5921	165	1	j	j	PROPN
dpc-5921	165	2	eur	eur	PROPN
dpc-5921	165	3	acad	acad	PROPN
dpc-5921	165	4	dermatol	dermatol	NOUN
dpc-5921	165	5	venereol	venereol	NOUN
dpc-5921	165	6	.	.	PUNCT
dpc-5921	166	1	2024;38(6	2024;38(6	NUM
dpc-5921	166	2	):	):	PUNCT
dpc-5921	166	3	1024	1024	NUM
dpc-5921	166	4	-	-	SYM
dpc-5921	166	5	1047	1047	NUM
dpc-5921	166	6	.	.	PUNCT
dpc-5921	167	1	doi	doi	NOUN
dpc-5921	167	2	:	:	PUNCT
dpc-5921	167	3	10.1111	10.1111	NUM
dpc-5921	167	4	/	/	SYM
dpc-5921	167	5	jdv.19897	jdv.19897	NUM
dpc-5921	167	6	.	.	PUNCT
dpc-5921	168	1	2	2	X
dpc-5921	168	2	.	.	X
dpc-5921	168	3	malvehy	malvehy	PROPN
dpc-5921	168	4	j	j	PROPN
dpc-5921	168	5	,	,	PUNCT
dpc-5921	168	6	stratigos	stratigos	PROPN
dpc-5921	168	7	aj	aj	PROPN
dpc-5921	168	8	,	,	PUNCT
dpc-5921	168	9	bagot	bagot	PROPN
dpc-5921	168	10	m	m	PROPN
dpc-5921	168	11	,	,	PUNCT
dpc-5921	168	12	stockfleth	stockfleth	PROPN
dpc-5921	168	13	e	e	PROPN
dpc-5921	168	14	,	,	PUNCT
dpc-5921	168	15	ezzedine	ezzedine	PROPN
dpc-5921	168	16	k	k	NOUN
dpc-5921	168	17	,	,	PUNCT
dpc-5921	168	18	delarue	delarue	ADJ
dpc-5921	168	19	a.	a.	NOUN
dpc-5921	168	20	actinic	actinic	ADJ
dpc-5921	168	21	keratosis	keratosis	NOUN
dpc-5921	168	22	:	:	PUNCT
dpc-5921	168	23	current	current	ADJ
dpc-5921	168	24	challenges	challenge	NOUN
dpc-5921	168	25	and	and	CCONJ
dpc-5921	168	26	unanswered	unanswered	ADJ
dpc-5921	168	27	questions	question	NOUN
dpc-5921	168	28	.	.	PUNCT
dpc-5921	169	1	j	j	PROPN
dpc-5921	169	2	eur	eur	PROPN
dpc-5921	169	3	acad	acad	PROPN
dpc-5921	169	4	dermatol	dermatol	NOUN
dpc-5921	169	5	venereol	venereol	NOUN
dpc-5921	169	6	.	.	PUNCT
dpc-5921	170	1	2024;38	2024;38	NUM
dpc-5921	170	2	suppl	suppl	ADJ
dpc-5921	170	3	5:3	5:3	NUM
dpc-5921	170	4	-	-	SYM
dpc-5921	170	5	11	11	NUM
dpc-5921	170	6	.	.	PUNCT
dpc-5921	171	1	doi	doi	NOUN
dpc-5921	171	2	:	:	PUNCT
dpc-5921	171	3	10.1111	10.1111	NUM
dpc-5921	171	4	/	/	SYM
dpc-5921	171	5	jdv.19559	jdv.19559	PROPN
dpc-5921	171	6	.	.	PUNCT
dpc-5921	172	1	pmid	pmid	NOUN
dpc-5921	172	2	:	:	PUNCT
dpc-5921	172	3	38923589	38923589	NUM
dpc-5921	172	4	.	.	PUNCT
dpc-5921	173	1	3	3	X
dpc-5921	173	2	.	.	X
dpc-5921	173	3	valenti	valenti	PROPN
dpc-5921	173	4	m	m	PROPN
dpc-5921	173	5	,	,	PUNCT
dpc-5921	173	6	bianco	bianco	PROPN
dpc-5921	173	7	m	m	PROPN
dpc-5921	173	8	,	,	PUNCT
dpc-5921	173	9	narcisi	narcisi	ADV
dpc-5921	173	10	a	a	PRON
dpc-5921	173	11	,	,	PUNCT
dpc-5921	173	12	costanzo	costanzo	PROPN
dpc-5921	173	13	a	a	PRON
dpc-5921	173	14	,	,	PUNCT
dpc-5921	173	15	borroni	borroni	NOUN
dpc-5921	173	16	r	r	NOUN
dpc-5921	173	17	,	,	PUNCT
dpc-5921	173	18	ardigò	ardigò	NOUN
dpc-5921	173	19	m.	m.	NOUN
dpc-5921	173	20	topical	topical	ADJ
dpc-5921	173	21	pharmacological	pharmacological	ADJ
dpc-5921	173	22	treatment	treatment	NOUN
dpc-5921	173	23	of	of	ADP
dpc-5921	173	24	actinic	actinic	ADJ
dpc-5921	173	25	keratoses	keratose	NOUN
dpc-5921	173	26	:	:	PUNCT
dpc-5921	173	27	focus	focus	VERB
dpc-5921	173	28	on	on	ADP
dpc-5921	173	29	tirbanibulin	tirbanibulin	PROPN
dpc-5921	173	30	1	1	NUM
dpc-5921	173	31	%	%	NOUN
dpc-5921	173	32	ointment	ointment	NOUN
dpc-5921	173	33	.	.	PUNCT
dpc-5921	174	1	dermatol	dermatol	NOUN
dpc-5921	174	2	pract	pract	PROPN
dpc-5921	174	3	concept	concept	NOUN
dpc-5921	174	4	.	.	PUNCT
dpc-5921	175	1	2024;14(3	2024;14(3	NUM
dpc-5921	175	2	s1	s1	NOUN
dpc-5921	175	3	)	)	PUNCT
dpc-5921	175	4	.	.	PUNCT
dpc-5921	176	1	doi	doi	NOUN
dpc-5921	176	2	:	:	PUNCT
dpc-5921	176	3	10.5826	10.5826	NUM
dpc-5921	176	4	/	/	SYM
dpc-5921	176	5	dpc.1403s1a145s	dpc.1403s1a145s	NOUN
dpc-5921	176	6	.	.	PUNCT
dpc-5921	177	1	pmid	pmid	NOUN
dpc-5921	177	2	:	:	PUNCT
dpc-5921	177	3	3913	3913	NUM
dpc-5921	177	4	3636	3636	NUM
dpc-5921	177	5	.	.	PUNCT
dpc-5921	178	1	4	4	X
dpc-5921	178	2	.	.	X
dpc-5921	178	3	arcuri	arcuri	PROPN
dpc-5921	178	4	d	d	PROPN
dpc-5921	178	5	,	,	PUNCT
dpc-5921	178	6	ramchatesingh	ramchatesingh	PROPN
dpc-5921	178	7	b	b	NOUN
dpc-5921	178	8	,	,	PUNCT
dpc-5921	178	9	lagacé	lagacé	NOUN
dpc-5921	178	10	f	f	PROPN
dpc-5921	178	11	,	,	PUNCT
dpc-5921	178	12	et	et	PROPN
dpc-5921	178	13	al	al	PROPN
dpc-5921	178	14	.	.	PROPN
dpc-5921	179	1	pharmacological	pharmacological	ADJ
dpc-5921	179	2	agents	agent	NOUN
dpc-5921	179	3	used	use	VERB
dpc-5921	179	4	in	in	ADP
dpc-5921	179	5	the	the	DET
dpc-5921	179	6	prevention	prevention	NOUN
dpc-5921	179	7	and	and	CCONJ
dpc-5921	179	8	treatment	treatment	NOUN
dpc-5921	179	9	of	of	ADP
dpc-5921	179	10	actinic	actinic	ADJ
dpc-5921	179	11	keratosis	keratosis	NOUN
dpc-5921	179	12	:	:	PUNCT
dpc-5921	179	13	a	a	DET
dpc-5921	179	14	review	review	NOUN
dpc-5921	179	15	.	.	PUNCT
dpc-5921	180	1	int	int	PROPN
dpc-5921	180	2	j	j	PROPN
dpc-5921	180	3	mol	mol	ADP
dpc-5921	180	4	sci	sci	PROPN
dpc-5921	180	5	.	.	PUNCT
dpc-5921	181	1	2023;24(5):4989	2023;24(5):4989	NUM
dpc-5921	181	2	.	.	PUNCT
dpc-5921	182	1	doi	doi	NOUN
dpc-5921	182	2	:	:	PUNCT
dpc-5921	182	3	10.3390	10.3390	NUM
dpc-5921	182	4	/ijms24054989	/ijms24054989	PUNCT
dpc-5921	182	5	.	.	PUNCT
dpc-5921	183	1	pmid	pmid	NOUN
dpc-5921	183	2	:	:	PUNCT
dpc-5921	183	3	36902419	36902419	NUM
dpc-5921	183	4	.	.	PUNCT
dpc-5921	184	1	5	5	X
dpc-5921	184	2	.	.	X
dpc-5921	184	3	aggarwal	aggarwal	NOUN
dpc-5921	184	4	i	i	PRON
dpc-5921	184	5	,	,	PUNCT
dpc-5921	184	6	puyana	puyana	PROPN
dpc-5921	184	7	c	c	PROPN
dpc-5921	184	8	,	,	PUNCT
dpc-5921	184	9	chandan	chandan	PROPN
dpc-5921	184	10	n	n	CCONJ
dpc-5921	184	11	,	,	PUNCT
dpc-5921	184	12	jetter	jetter	PROPN
dpc-5921	184	13	n	n	CCONJ
dpc-5921	184	14	,	,	PUNCT
dpc-5921	184	15	tsoukas	tsoukas	PROPN
dpc-5921	184	16	m.	m.	NOUN
dpc-5921	184	17	field	field	PROPN
dpc-5921	184	18	cancerization	cancerization	NOUN
dpc-5921	184	19	therapies	therapy	NOUN
dpc-5921	184	20	for	for	ADP
dpc-5921	184	21	the	the	DET
dpc-5921	184	22	management	management	NOUN
dpc-5921	184	23	of	of	ADP
dpc-5921	184	24	actinic	actinic	ADJ
dpc-5921	184	25	keratosis	keratosis	NOUN
dpc-5921	184	26	:	:	PUNCT
dpc-5921	184	27	an	an	DET
dpc-5921	184	28	updated	update	VERB
dpc-5921	184	29	review	review	NOUN
dpc-5921	184	30	.	.	PUNCT
dpc-5921	185	1	am	be	AUX
dpc-5921	185	2	j	j	PROPN
dpc-5921	185	3	clin	clin	PROPN
dpc-5921	185	4	dermatol	dermatol	NOUN
dpc-5921	185	5	.	.	PUNCT
dpc-5921	186	1	2024;25(3):391	2024;25(3):391	NUM
dpc-5921	186	2	-	-	PUNCT
dpc-5921	186	3	405	405	NUM
dpc-5921	186	4	.	.	PUNCT
dpc-5921	187	1	doi	doi	NOUN
dpc-5921	187	2	:	:	PUNCT
dpc-5921	187	3	10.1007	10.1007	NUM
dpc-5921	187	4	/	/	SYM
dpc-5921	187	5	s40257	s40257	NOUN
dpc-5921	187	6	-	-	PUNCT
dpc-5921	187	7	023	023	NUM
dpc-5921	187	8	-	-	PUNCT
dpc-5921	187	9	00839	00839	NUM
dpc-5921	187	10	-	-	PUNCT
dpc-5921	187	11	8	8	NUM
dpc-5921	187	12	.	.	PUNCT
dpc-5921	188	1	pmid	pmid	NOUN
dpc-5921	188	2	:	:	PUNCT
dpc-5921	188	3	38351246	38351246	NUM
dpc-5921	188	4	.	.	PUNCT
dpc-5921	189	1	6	6	NUM
dpc-5921	189	2	.	.	X
dpc-5921	189	3	dao	dao	AUX
dpc-5921	189	4	dd	dd	VERB
dpc-5921	189	5	,	,	PUNCT
dpc-5921	189	6	sahni	sahni	PROPN
dpc-5921	189	7	vn	vn	PROPN
dpc-5921	189	8	,	,	PUNCT
dpc-5921	189	9	sahni	sahni	PROPN
dpc-5921	189	10	dr	dr	PROPN
dpc-5921	189	11	,	,	PUNCT
dpc-5921	189	12	balogh	balogh	PROPN
dpc-5921	189	13	ea	ea	PROPN
dpc-5921	189	14	,	,	PUNCT
dpc-5921	189	15	grada	grada	PROPN
dpc-5921	189	16	a	a	PROPN
dpc-5921	189	17	,	,	PUNCT
dpc-5921	189	18	feldman	feldman	PROPN
dpc-5921	189	19	sr	sr	PROPN
dpc-5921	189	20	.	.	PUNCT
dpc-5921	190	1	1	1	NUM
dpc-5921	190	2	%	%	NOUN
dpc-5921	190	3	tirbanibulin	tirbanibulin	PROPN
dpc-5921	190	4	ointment	ointment	NOUN
dpc-5921	190	5	for	for	ADP
dpc-5921	190	6	the	the	DET
dpc-5921	190	7	treatment	treatment	NOUN
dpc-5921	190	8	of	of	ADP
dpc-5921	190	9	actinic	actinic	ADJ
dpc-5921	190	10	keratoses	keratose	NOUN
dpc-5921	190	11	.	.	PUNCT
dpc-5921	191	1	ann	ann	PROPN
dpc-5921	191	2	pharmacother	pharmacother	PROPN
dpc-5921	191	3	.	.	PUNCT
dpc-5921	192	1	2022;56(4):494	2022;56(4):494	NUM
dpc-5921	192	2	-	-	SYM
dpc-5921	192	3	500	500	NUM
dpc-5921	192	4	.	.	PUNCT
dpc-5921	193	1	doi	doi	NOUN
dpc-5921	193	2	:	:	PUNCT
dpc-5921	193	3	10.1177/10600280211031329	10.1177/10600280211031329	NUM
dpc-5921	193	4	.	.	PUNCT
dpc-5921	194	1	pmid	pmid	NOUN
dpc-5921	194	2	:	:	PUNCT
dpc-5921	194	3	34301153	34301153	NUM
dpc-5921	194	4	.	.	PUNCT
dpc-5921	195	1	7	7	X
dpc-5921	195	2	.	.	X
dpc-5921	195	3	eisen	eisen	PROPN
dpc-5921	195	4	db	db	PROPN
dpc-5921	195	5	,	,	PUNCT
dpc-5921	195	6	dellavalle	dellavalle	PROPN
dpc-5921	195	7	rp	rp	NOUN
dpc-5921	195	8	,	,	PUNCT
dpc-5921	195	9	frazer	frazer	NOUN
dpc-5921	195	10	-	-	PUNCT
dpc-5921	195	11	green	green	PROPN
dpc-5921	195	12	l	l	PROPN
dpc-5921	195	13	,	,	PUNCT
dpc-5921	195	14	schlesinger	schlesinger	PROPN
dpc-5921	195	15	te	te	PROPN
dpc-5921	195	16	,	,	PUNCT
dpc-5921	195	17	shive	shive	PROPN
dpc-5921	195	18	m	m	PROPN
dpc-5921	195	19	,	,	PUNCT
dpc-5921	195	20	wu	wu	PROPN
dpc-5921	195	21	pa	pa	PROPN
dpc-5921	195	22	.	.	PROPN
dpc-5921	195	23	focused	focus	VERB
dpc-5921	195	24	update	update	NOUN
dpc-5921	195	25	:	:	PUNCT
dpc-5921	195	26	guidelines	guideline	NOUN
dpc-5921	195	27	of	of	ADP
dpc-5921	195	28	care	care	NOUN
dpc-5921	195	29	for	for	ADP
dpc-5921	195	30	the	the	DET
dpc-5921	195	31	management	management	NOUN
dpc-5921	195	32	of	of	ADP
dpc-5921	195	33	actinic	actinic	ADJ
dpc-5921	195	34	keratosis	keratosis	NOUN
dpc-5921	195	35	.	.	PUNCT
dpc-5921	196	1	j	j	PROPN
dpc-5921	196	2	am	be	AUX
dpc-5921	196	3	acad	acad	ADJ
dpc-5921	196	4	dermatol	dermatol	NOUN
dpc-5921	196	5	.	.	PUNCT
dpc-5921	197	1	2022;87(2	2022;87(2	NUM
dpc-5921	197	2	):	):	PUNCT
dpc-5921	197	3	373	373	NUM
dpc-5921	197	4	-	-	SYM
dpc-5921	197	5	374.e5	374.e5	NUM
dpc-5921	197	6	.	.	PUNCT
dpc-5921	198	1	doi	doi	NOUN
dpc-5921	198	2	:	:	PUNCT
dpc-5921	198	3	10.1016	10.1016	NUM
dpc-5921	198	4	/	/	SYM
dpc-5921	198	5	j.jaad.2022.04.013	j.jaad.2022.04.013	PROPN
dpc-5921	198	6	.	.	PUNCT
dpc-5921	199	1	pmid	pmid	PROPN
dpc-5921	199	2	:	:	PUNCT
dpc-5921	199	3	35439607	35439607	NUM
dpc-5921	199	4	.	.	PUNCT
dpc-5921	200	1	8	8	X
dpc-5921	200	2	.	.	X
dpc-5921	200	3	blauvelt	blauvelt	VERB
dpc-5921	200	4	a	a	PRON
dpc-5921	200	5	,	,	PUNCT
dpc-5921	200	6	kempers	kemper	NOUN
dpc-5921	200	7	s	s	PROPN
dpc-5921	200	8	,	,	PUNCT
dpc-5921	200	9	lain	lain	PROPN
dpc-5921	200	10	e	e	NOUN
dpc-5921	200	11	,	,	PUNCT
dpc-5921	200	12	et	et	PROPN
dpc-5921	200	13	al	al	PROPN
dpc-5921	200	14	.	.	PROPN
dpc-5921	200	15	,	,	PUNCT
dpc-5921	200	16	phase	phase	NOUN
dpc-5921	200	17	3	3	NUM
dpc-5921	200	18	tirbanibulin	tirbanibulin	NOUN
dpc-5921	200	19	for	for	ADP
dpc-5921	200	20	actinic	actinic	ADJ
dpc-5921	200	21	keratosis	keratosis	NOUN
dpc-5921	200	22	group	group	NOUN
dpc-5921	200	23	.	.	PUNCT
dpc-5921	201	1	phase	phase	NOUN
dpc-5921	201	2	3	3	NUM
dpc-5921	201	3	trials	trial	NOUN
dpc-5921	201	4	of	of	ADP
dpc-5921	201	5	tirbanibulin	tirbanibulin	PROPN
dpc-5921	201	6	ointment	ointment	NOUN
dpc-5921	201	7	for	for	ADP
dpc-5921	201	8	actinic	actinic	ADJ
dpc-5921	201	9	keratosis	keratosis	NOUN
dpc-5921	201	10	.	.	PUNCT
dpc-5921	202	1	n	n	PROPN
dpc-5921	202	2	engl	engl	PROPN
dpc-5921	202	3	j	j	PROPN
dpc-5921	202	4	med	me	VERB
dpc-5921	202	5	.	.	PUNCT
dpc-5921	203	1	2021;384(6):512	2021;384(6):512	NUM
dpc-5921	203	2	-	-	SYM
dpc-5921	203	3	520	520	NUM
dpc-5921	203	4	.	.	PUNCT
dpc-5921	203	5	doi	doi	NOUN
dpc-5921	203	6	:	:	PUNCT
dpc-5921	203	7	10.1056	10.1056	NUM
dpc-5921	203	8	/	/	SYM
dpc-5921	203	9	nejmoa2024040	nejmoa2024040	NOUN
dpc-5921	203	10	.	.	PUNCT
dpc-5921	204	1	pmid	pmid	NOUN
dpc-5921	204	2	:	:	PUNCT
dpc-5921	204	3	33567191	33567191	NUM
dpc-5921	204	4	.	.	PUNCT
dpc-5921	205	1	9	9	X
dpc-5921	205	2	.	.	X
dpc-5921	205	3	nazzaro	nazzaro	NOUN
dpc-5921	205	4	g	g	NOUN
dpc-5921	205	5	,	,	PUNCT
dpc-5921	205	6	carugno	carugno	VERB
dpc-5921	205	7	a	a	DET
dpc-5921	205	8	,	,	PUNCT
dpc-5921	205	9	bortoluzzi	bortoluzzi	NOUN
dpc-5921	205	10	p	p	NOUN
dpc-5921	205	11	,	,	PUNCT
dpc-5921	205	12	et	et	PROPN
dpc-5921	205	13	al	al	PROPN
dpc-5921	205	14	.	.	PROPN
dpc-5921	205	15	efficacy	efficacy	NOUN
dpc-5921	205	16	and	and	CCONJ
dpc-5921	205	17	tolerability	tolerability	NOUN
dpc-5921	205	18	of	of	ADP
dpc-5921	205	19	tirbanibulin	tirbanibulin	DET
dpc-5921	205	20	1	1	NUM
dpc-5921	205	21	%	%	NOUN
dpc-5921	205	22	ointment	ointment	NOUN
dpc-5921	205	23	in	in	ADP
dpc-5921	205	24	the	the	DET
dpc-5921	205	25	treatment	treatment	NOUN
dpc-5921	205	26	of	of	ADP
dpc-5921	205	27	cancerization	cancerization	NOUN
dpc-5921	205	28	field	field	NOUN
dpc-5921	205	29	:	:	PUNCT
dpc-5921	205	30	a	a	DET
dpc-5921	205	31	real	real	ADJ
dpc-5921	205	32	-	-	PUNCT
dpc-5921	205	33	life	life	NOUN
dpc-5921	205	34	italian	italian	ADJ
dpc-5921	205	35	multicenter	multicenter	NOUN
dpc-5921	205	36	observational	observational	ADJ
dpc-5921	205	37	study	study	NOUN
dpc-5921	205	38	of	of	ADP
dpc-5921	205	39	250	250	NUM
dpc-5921	205	40	patients	patient	NOUN
dpc-5921	205	41	.	.	PUNCT
dpc-5921	206	1	int	int	NOUN
dpc-5921	206	2	j	j	PROPN
dpc-5921	206	3	dermatol	dermatol	NOUN
dpc-5921	206	4	.	.	PUNCT
dpc-5921	207	1	2024;63(11):1566	2024;63(11):1566	X
dpc-5921	207	2	-	-	SYM
dpc-5921	207	3	1574	1574	NUM
dpc-5921	207	4	.	.	PUNCT
dpc-5921	208	1	doi	doi	NOUN
dpc-5921	208	2	:	:	PUNCT
dpc-5921	208	3	10.1111	10.1111	NUM
dpc-5921	208	4	/	/	SYM
dpc-5921	208	5	ijd.17168	ijd.17168	PROPN
dpc-5921	208	6	.	.	PUNCT
dpc-5921	209	1	pmid	pmid	NOUN
dpc-5921	209	2	:	:	PUNCT
dpc-5921	209	3	38605473	38605473	NUM
dpc-5921	209	4	.	.	PUNCT
dpc-5921	210	1	10	10	NUM
dpc-5921	210	2	.	.	PUNCT
dpc-5921	211	1	campione	campione	PROPN
dpc-5921	211	2	e	e	PROPN
dpc-5921	211	3	,	,	PUNCT
dpc-5921	211	4	rivieccio	rivieccio	VERB
dpc-5921	211	5	a	a	PRON
dpc-5921	211	6	,	,	PUNCT
dpc-5921	211	7	gaeta	gaeta	PROPN
dpc-5921	211	8	shumak	shumak	PROPN
dpc-5921	211	9	r	r	PROPN
dpc-5921	211	10	,	,	PUNCT
dpc-5921	211	11	et	et	PROPN
dpc-5921	211	12	al	al	PROPN
dpc-5921	211	13	.	.	PROPN
dpc-5921	212	1	preliminary	preliminary	ADJ
dpc-5921	212	2	evidence	evidence	NOUN
dpc-5921	212	3	of	of	ADP
dpc-5921	212	4	efficacy	efficacy	NOUN
dpc-5921	212	5	,	,	PUNCT
dpc-5921	212	6	safety	safety	NOUN
dpc-5921	212	7	,	,	PUNCT
dpc-5921	212	8	and	and	CCONJ
dpc-5921	212	9	treatment	treatment	NOUN
dpc-5921	212	10	satisfaction	satisfaction	NOUN
dpc-5921	212	11	with	with	ADP
dpc-5921	212	12	tirbanibulin	tirbanibulin	PROPN
dpc-5921	212	13	1	1	NUM
dpc-5921	212	14	%	%	NOUN
dpc-5921	212	15	ointment	ointment	NOUN
dpc-5921	212	16	:	:	PUNCT
dpc-5921	212	17	a	a	DET
dpc-5921	212	18	clinical	clinical	ADJ
dpc-5921	212	19	perspective	perspective	NOUN
dpc-5921	212	20	on	on	ADP
dpc-5921	212	21	actinic	actinic	ADJ
dpc-5921	212	22	keratoses	keratose	NOUN
dpc-5921	212	23	.	.	PUNCT
dpc-5921	213	1	pharmaceuticals	pharmaceutical	NOUN
dpc-5921	213	2	(	(	PUNCT
dpc-5921	213	3	basel	basel	PROPN
dpc-5921	213	4	)	)	PUNCT
dpc-5921	213	5	.	.	PUNCT
dpc-5921	214	1	2023;16(12):1686	2023;16(12):1686	X
dpc-5921	214	2	.	.	X
dpc-5921	214	3	doi	doi	NOUN
dpc-5921	214	4	:	:	PUNCT
dpc-5921	214	5	10.3390	10.3390	NUM
dpc-5921	214	6	/	/	SYM
dpc-5921	214	7	ph16121686	ph16121686	PROPN
dpc-5921	214	8	.	.	PUNCT
dpc-5921	215	1	pmid	pmid	NOUN
dpc-5921	215	2	:	:	PUNCT
dpc-5921	215	3	38139813	38139813	NUM
dpc-5921	215	4	.	.	PUNCT
dpc-5921	216	1	the	the	DET
dpc-5921	216	2	pharmacokinetics	pharmacokinetic	NOUN
dpc-5921	216	3	and	and	CCONJ
dpc-5921	216	4	tolerability	tolerability	NOUN
dpc-5921	216	5	of	of	ADP
dpc-5921	216	6	tirbanibulin	tirbanibulin	PROPN
dpc-5921	216	7	ointment	ointment	NOUN
dpc-5921	216	8	when	when	SCONJ
dpc-5921	216	9	applied	apply	VERB
dpc-5921	216	10	to	to	ADP
dpc-5921	216	11	fields	field	NOUN
dpc-5921	216	12	larger	large	ADJ
dpc-5921	216	13	than	than	ADP
dpc-5921	216	14	25	25	NUM
dpc-5921	216	15	cm2	cm2	NOUN
dpc-5921	216	16	,	,	PUNCT
dpc-5921	216	17	supporting	support	VERB
dpc-5921	216	18	its	its	PRON
dpc-5921	216	19	use	use	NOUN
dpc-5921	216	20	(	(	PUNCT
dpc-5921	216	21	as	as	SCONJ
dpc-5921	216	22	one	one	NUM
dpc-5921	216	23	350	350	NUM
dpc-5921	216	24	mg	mg	PROPN
dpc-5921	216	25	sachet	sachet	NOUN
dpc-5921	216	26	applied	apply	VERB
dpc-5921	216	27	daily	daily	ADV
dpc-5921	216	28	)	)	PUNCT
dpc-5921	216	29	in	in	ADP
dpc-5921	216	30	fields	field	NOUN
dpc-5921	216	31	measuring	measure	VERB
dpc-5921	216	32	up	up	ADP
dpc-5921	216	33	to	to	PART
dpc-5921	216	34	100	100	NUM
dpc-5921	216	35	cm2	cm2	PROPN
dpc-5921	216	36	[	[	X
dpc-5921	216	37	40,41	40,41	PROPN
dpc-5921	216	38	]	]	X
dpc-5921	216	39	.	.	PUNCT
dpc-5921	217	1	the	the	DET
dpc-5921	217	2	safety	safety	NOUN
dpc-5921	217	3	and	and	CCONJ
dpc-5921	217	4	tolerability	tolerability	NOUN
dpc-5921	217	5	profiles	profile	NOUN
dpc-5921	217	6	of	of	ADP
dpc-5921	217	7	tirbanibulin	tirbanibulin	PROPN
dpc-5921	217	8	when	when	SCONJ
dpc-5921	217	9	used	use	VERB
dpc-5921	217	10	at	at	ADP
dpc-5921	217	11	approximately	approximately	ADV
dpc-5921	217	12	100	100	NUM
dpc-5921	217	13	cm2	cm2	NOUN
dpc-5921	217	14	fields	field	NOUN
dpc-5921	217	15	were	be	AUX
dpc-5921	217	16	found	find	VERB
dpc-5921	217	17	to	to	PART
dpc-5921	217	18	be	be	AUX
dpc-5921	217	19	consistent	consistent	ADJ
dpc-5921	217	20	with	with	ADP
dpc-5921	217	21	those	those	PRON
dpc-5921	217	22	reported	report	VERB
dpc-5921	217	23	for	for	ADP
dpc-5921	217	24	smaller	small	ADJ
dpc-5921	217	25	fields	field	NOUN
dpc-5921	217	26	,	,	PUNCT
dpc-5921	217	27	and	and	CCONJ
dpc-5921	217	28	exploratory	exploratory	ADJ
dpc-5921	217	29	efficacy	efficacy	NOUN
dpc-5921	217	30	data	datum	NOUN
dpc-5921	217	31	also	also	ADV
dpc-5921	217	32	suggest	suggest	VERB
dpc-5921	217	33	similar	similar	ADJ
dpc-5921	217	34	benefits	benefit	NOUN
dpc-5921	217	35	to	to	ADP
dpc-5921	217	36	those	those	PRON
dpc-5921	217	37	observed	observe	VERB
dpc-5921	217	38	with	with	ADP
dpc-5921	217	39	the	the	DET
dpc-5921	217	40	application	application	NOUN
dpc-5921	217	41	of	of	ADP
dpc-5921	217	42	tirbanibulin	tirbanibulin	PROPN
dpc-5921	217	43	over	over	ADP
dpc-5921	217	44	a	a	DET
dpc-5921	217	45	more	more	ADV
dpc-5921	217	46	restricted	restricted	ADJ
dpc-5921	217	47	area	area	NOUN
dpc-5921	217	48	[	[	X
dpc-5921	217	49	41	41	NUM
dpc-5921	217	50	]	]	PUNCT
dpc-5921	217	51	.	.	PUNCT
dpc-5921	218	1	according	accord	VERB
dpc-5921	218	2	to	to	ADP
dpc-5921	218	3	this	this	DET
dpc-5921	218	4	expert	expert	ADJ
dpc-5921	218	5	panel	panel	NOUN
dpc-5921	218	6	’s	’s	PART
dpc-5921	218	7	experience	experience	NOUN
dpc-5921	218	8	,	,	PUNCT
dpc-5921	218	9	more	more	ADJ
dpc-5921	218	10	than	than	ADP
dpc-5921	218	11	25	25	NUM
dpc-5921	218	12	cm2	cm2	NOUN
dpc-5921	218	13	can	can	AUX
dpc-5921	218	14	be	be	AUX
dpc-5921	218	15	treated	treat	VERB
dpc-5921	218	16	by	by	ADP
dpc-5921	218	17	one	one	NUM
dpc-5921	218	18	sachet	sachet	NOUN
dpc-5921	218	19	of	of	ADP
dpc-5921	218	20	tirbanibulin	tirbanibulin	PROPN
dpc-5921	218	21	1	1	NUM
dpc-5921	218	22	%	%	NOUN
dpc-5921	218	23	ointment	ointment	NOUN
dpc-5921	218	24	.	.	PUNCT
dpc-5921	219	1	the	the	DET
dpc-5921	219	2	standard	standard	ADJ
dpc-5921	219	3	period	period	NOUN
dpc-5921	219	4	of	of	ADP
dpc-5921	219	5	treatment	treatment	NOUN
dpc-5921	219	6	with	with	ADP
dpc-5921	219	7	tirbanibulin	tirbanibulin	PROPN
dpc-5921	219	8	is	be	AUX
dpc-5921	219	9	five	five	NUM
dpc-5921	219	10	days	day	NOUN
dpc-5921	219	11	.	.	PUNCT
dpc-5921	220	1	however	however	ADV
dpc-5921	220	2	,	,	PUNCT
dpc-5921	220	3	owing	owe	VERB
dpc-5921	220	4	to	to	ADP
dpc-5921	220	5	the	the	DET
dpc-5921	220	6	favorable	favorable	ADJ
dpc-5921	220	7	tolerability	tolerability	NOUN
dpc-5921	220	8	profile	profile	NOUN
dpc-5921	220	9	of	of	ADP
dpc-5921	220	10	the	the	DET
dpc-5921	220	11	drug	drug	NOUN
dpc-5921	220	12	,	,	PUNCT
dpc-5921	220	13	various	various	ADJ
dpc-5921	220	14	protocols	protocol	NOUN
dpc-5921	220	15	are	be	AUX
dpc-5921	220	16	possible	possible	ADJ
dpc-5921	220	17	.	.	PUNCT
dpc-5921	221	1	forward	forward	ADJ
dpc-5921	221	2	planning	planning	NOUN
dpc-5921	221	3	of	of	ADP
dpc-5921	221	4	the	the	DET
dpc-5921	221	5	treatment	treatment	NOUN
dpc-5921	221	6	regimen	regiman	NOUN
dpc-5921	221	7	(	(	PUNCT
dpc-5921	221	8	including	include	VERB
dpc-5921	221	9	repeated	repeat	VERB
dpc-5921	221	10	treatment	treatment	NOUN
dpc-5921	221	11	of	of	ADP
dpc-5921	221	12	severely	severely	ADV
dpc-5921	221	13	affected	affect	VERB
dpc-5921	221	14	areas	area	NOUN
dpc-5921	221	15	)	)	PUNCT
dpc-5921	221	16	is	be	AUX
dpc-5921	221	17	always	always	ADV
dpc-5921	221	18	advisable	advisable	ADJ
dpc-5921	221	19	.	.	PUNCT
dpc-5921	222	1	when	when	SCONJ
dpc-5921	222	2	treating	treat	VERB
dpc-5921	222	3	large	large	ADJ
dpc-5921	222	4	fields	field	NOUN
dpc-5921	222	5	(	(	PUNCT
dpc-5921	222	6	>	>	X
dpc-5921	222	7	25	25	NUM
dpc-5921	222	8	cm2	cm2	NOUN
dpc-5921	222	9	)	)	PUNCT
dpc-5921	222	10	,	,	PUNCT
dpc-5921	222	11	sequential	sequential	ADJ
dpc-5921	222	12	or	or	CCONJ
dpc-5921	222	13	simultaneous	simultaneous	ADJ
dpc-5921	222	14	therapeutic	therapeutic	ADJ
dpc-5921	222	15	schedules	schedule	NOUN
dpc-5921	222	16	can	can	AUX
dpc-5921	222	17	be	be	AUX
dpc-5921	222	18	considered	consider	VERB
dpc-5921	222	19	.	.	PUNCT
dpc-5921	223	1	up	up	ADP
dpc-5921	223	2	to	to	PART
dpc-5921	223	3	four	four	NUM
dpc-5921	223	4	consecutive	consecutive	ADJ
dpc-5921	223	5	treatment	treatment	NOUN
dpc-5921	223	6	cycles	cycle	NOUN
dpc-5921	223	7	one	one	NUM
dpc-5921	223	8	to	to	ADP
dpc-5921	223	9	two	two	NUM
dpc-5921	223	10	months	month	NOUN
dpc-5921	223	11	apart	apart	ADV
dpc-5921	223	12	can	can	AUX
dpc-5921	223	13	be	be	AUX
dpc-5921	223	14	planned	plan	VERB
dpc-5921	223	15	if	if	SCONJ
dpc-5921	223	16	needed	need	VERB
dpc-5921	223	17	,	,	PUNCT
dpc-5921	223	18	based	base	VERB
dpc-5921	223	19	on	on	ADP
dpc-5921	223	20	disease	disease	NOUN
dpc-5921	223	21	and	and	CCONJ
dpc-5921	223	22	patient	patient	ADJ
dpc-5921	223	23	characteristics	characteristic	NOUN
dpc-5921	223	24	.	.	PUNCT
dpc-5921	224	1	multiple	multiple	ADJ
dpc-5921	224	2	treatment	treatment	NOUN
dpc-5921	224	3	cycles	cycle	NOUN
dpc-5921	224	4	can	can	AUX
dpc-5921	224	5	be	be	AUX
dpc-5921	224	6	performed	perform	VERB
dpc-5921	224	7	in	in	ADP
dpc-5921	224	8	immunocompromised	immunocompromise	VERB
dpc-5921	224	9	patients	patient	NOUN
dpc-5921	224	10	,	,	PUNCT
dpc-5921	224	11	those	those	PRON
dpc-5921	224	12	with	with	ADP
dpc-5921	224	13	a	a	DET
dpc-5921	224	14	history	history	NOUN
dpc-5921	224	15	of	of	ADP
dpc-5921	224	16	skin	skin	NOUN
dpc-5921	224	17	cancer	cancer	NOUN
dpc-5921	224	18	,	,	PUNCT
dpc-5921	224	19	and	and	CCONJ
dpc-5921	224	20	those	those	PRON
dpc-5921	224	21	with	with	ADP
dpc-5921	224	22	advanced	advanced	ADJ
dpc-5921	224	23	photodamage	photodamage	NOUN
dpc-5921	224	24	.	.	PUNCT
dpc-5921	225	1	good	good	ADJ
dpc-5921	225	2	communication	communication	NOUN
dpc-5921	225	3	with	with	ADP
dpc-5921	225	4	the	the	DET
dpc-5921	225	5	patient	patient	NOUN
dpc-5921	225	6	is	be	AUX
dpc-5921	225	7	essential	essential	ADJ
dpc-5921	225	8	in	in	ADP
dpc-5921	225	9	the	the	DET
dpc-5921	225	10	long	long	ADJ
dpc-5921	225	11	-	-	PUNCT
dpc-5921	225	12	term	term	NOUN
dpc-5921	225	13	management	management	NOUN
dpc-5921	225	14	of	of	ADP
dpc-5921	225	15	ak	ak	PROPN
dpc-5921	225	16	.	.	PROPN
dpc-5921	225	17	clinicians	clinician	NOUN
dpc-5921	225	18	should	should	AUX
dpc-5921	225	19	understand	understand	VERB
dpc-5921	225	20	the	the	DET
dpc-5921	225	21	patient	patient	NOUN
dpc-5921	225	22	’s	’s	PART
dpc-5921	225	23	priorities	priority	NOUN
dpc-5921	225	24	and	and	CCONJ
dpc-5921	225	25	concerns	concern	NOUN
dpc-5921	225	26	,	,	PUNCT
dpc-5921	225	27	setting	set	VERB
dpc-5921	225	28	realistic	realistic	ADJ
dpc-5921	225	29	treatment	treatment	NOUN
dpc-5921	225	30	expectations	expectation	NOUN
dpc-5921	226	1	[	[	X
dpc-5921	226	2	26	26	NUM
dpc-5921	226	3	]	]	PUNCT
dpc-5921	226	4	.	.	PUNCT
dpc-5921	227	1	patient	patient	NOUN
dpc-5921	227	2	should	should	AUX
dpc-5921	227	3	be	be	AUX
dpc-5921	227	4	informed	inform	VERB
dpc-5921	227	5	about	about	ADP
dpc-5921	227	6	the	the	DET
dpc-5921	227	7	chronic	chronic	ADJ
dpc-5921	227	8	nature	nature	NOUN
dpc-5921	227	9	of	of	ADP
dpc-5921	227	10	ak	ak	PROPN
dpc-5921	227	11	,	,	PUNCT
dpc-5921	227	12	the	the	DET
dpc-5921	227	13	unpredictable	unpredictable	ADJ
dpc-5921	227	14	evolution	evolution	NOUN
dpc-5921	227	15	of	of	ADP
dpc-5921	227	16	ak	ak	PROPN
dpc-5921	227	17	lesions	lesion	NOUN
dpc-5921	227	18	,	,	PUNCT
dpc-5921	227	19	and	and	CCONJ
dpc-5921	227	20	the	the	DET
dpc-5921	227	21	high	high	ADJ
dpc-5921	227	22	rates	rate	NOUN
dpc-5921	227	23	of	of	ADP
dpc-5921	227	24	recurrence	recurrence	NOUN
dpc-5921	227	25	,	,	PUNCT
dpc-5921	227	26	hence	hence	ADV
dpc-5921	227	27	the	the	DET
dpc-5921	227	28	need	need	NOUN
dpc-5921	227	29	for	for	ADP
dpc-5921	227	30	repeated	repeat	VERB
dpc-5921	227	31	treatment	treatment	NOUN
dpc-5921	227	32	courses	course	NOUN
dpc-5921	227	33	over	over	ADP
dpc-5921	227	34	time	time	NOUN
dpc-5921	227	35	.	.	PUNCT
dpc-5921	228	1	it	it	PRON
dpc-5921	228	2	is	be	AUX
dpc-5921	228	3	particularly	particularly	ADV
dpc-5921	228	4	important	important	ADJ
dpc-5921	228	5	to	to	PART
dpc-5921	228	6	inform	inform	VERB
dpc-5921	228	7	patients	patient	NOUN
dpc-5921	228	8	about	about	ADP
dpc-5921	228	9	the	the	DET
dpc-5921	228	10	occurrence	occurrence	NOUN
dpc-5921	228	11	and	and	CCONJ
dpc-5921	228	12	transient	transient	VERB
dpc-5921	228	13	nature	nature	NOUN
dpc-5921	228	14	of	of	ADP
dpc-5921	228	15	local	local	ADJ
dpc-5921	228	16	skin	skin	NOUN
dpc-5921	228	17	reactions	reaction	NOUN
dpc-5921	228	18	associated	associate	VERB
dpc-5921	228	19	with	with	ADP
dpc-5921	228	20	tirbanibulin	tirbanibulin	PROPN
dpc-5921	228	21	treatment	treatment	NOUN
dpc-5921	228	22	.	.	PUNCT
dpc-5921	229	1	although	although	SCONJ
dpc-5921	229	2	skin	skin	NOUN
dpc-5921	229	3	reactions	reaction	NOUN
dpc-5921	229	4	are	be	AUX
dpc-5921	229	5	usually	usually	ADV
dpc-5921	229	6	mild	mild	ADJ
dpc-5921	229	7	,	,	PUNCT
dpc-5921	229	8	severe	severe	ADJ
dpc-5921	229	9	local	local	ADJ
dpc-5921	229	10	adverse	adverse	ADJ
dpc-5921	229	11	events	event	NOUN
dpc-5921	229	12	may	may	AUX
dpc-5921	229	13	occur	occur	VERB
dpc-5921	229	14	,	,	PUNCT
dpc-5921	229	15	and	and	CCONJ
dpc-5921	229	16	patients	patient	NOUN
dpc-5921	229	17	need	need	VERB
dpc-5921	229	18	reassurance	reassurance	NOUN
dpc-5921	229	19	that	that	SCONJ
dpc-5921	229	20	these	these	PRON
dpc-5921	229	21	will	will	AUX
dpc-5921	229	22	eventually	eventually	ADV
dpc-5921	229	23	resolve	resolve	VERB
dpc-5921	229	24	without	without	ADP
dpc-5921	229	25	sequelae	sequelae	PROPN
dpc-5921	229	26	.	.	PUNCT
dpc-5921	230	1	correct	correct	ADJ
dpc-5921	230	2	treatment	treatment	NOUN
dpc-5921	230	3	modalities	modality	NOUN
dpc-5921	230	4	are	be	AUX
dpc-5921	230	5	another	another	DET
dpc-5921	230	6	important	important	ADJ
dpc-5921	230	7	aspect	aspect	NOUN
dpc-5921	230	8	of	of	ADP
dpc-5921	230	9	care	care	NOUN
dpc-5921	230	10	that	that	PRON
dpc-5921	230	11	can	can	AUX
dpc-5921	230	12	affect	affect	VERB
dpc-5921	230	13	the	the	DET
dpc-5921	230	14	outcome	outcome	NOUN
dpc-5921	230	15	of	of	ADP
dpc-5921	230	16	therapy	therapy	NOUN
dpc-5921	230	17	.	.	PUNCT
dpc-5921	231	1	patients	patient	NOUN
dpc-5921	231	2	should	should	AUX
dpc-5921	231	3	be	be	AUX
dpc-5921	231	4	given	give	VERB
dpc-5921	231	5	detailed	detailed	ADJ
dpc-5921	231	6	instructions	instruction	NOUN
dpc-5921	231	7	about	about	ADP
dpc-5921	231	8	tirbanibulin	tirbanibulin	PROPN
dpc-5921	231	9	application	application	NOUN
dpc-5921	231	10	at	at	ADP
dpc-5921	231	11	home	home	NOUN
dpc-5921	231	12	.	.	PUNCT
dpc-5921	232	1	expert	expert	ADJ
dpc-5921	232	2	consensus	consensus	NOUN
dpc-5921	232	3	statements	statement	NOUN
dpc-5921	232	4	with	with	ADP
dpc-5921	232	5	recommendations	recommendation	NOUN
dpc-5921	232	6	on	on	ADP
dpc-5921	232	7	tirbanibulin	tirbanibulin	PROPN
dpc-5921	232	8	treatment	treatment	NOUN
dpc-5921	232	9	are	be	AUX
dpc-5921	232	10	reported	report	VERB
dpc-5921	232	11	in	in	ADP
dpc-5921	232	12	table	table	NOUN
dpc-5921	232	13	1(b	1(b	NUM
dpc-5921	232	14	)	)	PUNCT
dpc-5921	232	15	.	.	PUNCT
dpc-5921	233	1	conclusion	conclusion	NOUN
dpc-5921	233	2	with	with	ADP
dpc-5921	233	3	its	its	PRON
dpc-5921	233	4	novel	novel	ADJ
dpc-5921	233	5	mechanism	mechanism	NOUN
dpc-5921	233	6	of	of	ADP
dpc-5921	233	7	action	action	NOUN
dpc-5921	233	8	,	,	PUNCT
dpc-5921	233	9	proven	prove	VERB
dpc-5921	233	10	efficacy	efficacy	NOUN
dpc-5921	233	11	,	,	PUNCT
dpc-5921	233	12	good	good	ADJ
dpc-5921	233	13	tolerability	tolerability	NOUN
dpc-5921	233	14	,	,	PUNCT
dpc-5921	233	15	and	and	CCONJ
dpc-5921	233	16	short	short	ADJ
dpc-5921	233	17	duration	duration	NOUN
dpc-5921	233	18	of	of	ADP
dpc-5921	233	19	therapy	therapy	NOUN
dpc-5921	233	20	,	,	PUNCT
dpc-5921	233	21	tirbanibulin	tirbanibulin	PROPN
dpc-5921	233	22	is	be	AUX
dpc-5921	233	23	an	an	DET
dpc-5921	233	24	important	important	ADJ
dpc-5921	233	25	treatment	treatment	NOUN
dpc-5921	233	26	for	for	ADP
dpc-5921	233	27	the	the	DET
dpc-5921	233	28	management	management	NOUN
dpc-5921	233	29	of	of	ADP
dpc-5921	233	30	ak	ak	PROPN
dpc-5921	233	31	and	and	CCONJ
dpc-5921	233	32	should	should	AUX
dpc-5921	233	33	be	be	AUX
dpc-5921	233	34	considered	consider	VERB
dpc-5921	233	35	as	as	ADP
dpc-5921	233	36	a	a	DET
dpc-5921	233	37	first	first	ADJ
dpc-5921	233	38	-	-	PUNCT
dpc-5921	233	39	line	line	NOUN
dpc-5921	233	40	option	option	NOUN
dpc-5921	233	41	for	for	ADP
dpc-5921	233	42	most	most	ADJ
dpc-5921	233	43	patients	patient	NOUN
dpc-5921	233	44	,	,	PUNCT
dpc-5921	233	45	including	include	VERB
dpc-5921	233	46	treatment	treatment	NOUN
dpc-5921	233	47	-	-	PUNCT
dpc-5921	233	48	naïve	naïve	ADJ
dpc-5921	233	49	and	and	CCONJ
dpc-5921	233	50	pre	pre	ADJ
dpc-5921	233	51	-	-	ADJ
dpc-5921	233	52	treated	treat	VERB
dpc-5921	233	53	subjects	subject	NOUN
dpc-5921	233	54	as	as	ADV
dpc-5921	233	55	well	well	ADV
dpc-5921	233	56	as	as	ADP
dpc-5921	233	57	those	those	PRON
dpc-5921	233	58	with	with	ADP
dpc-5921	233	59	difficult	difficult	ADJ
dpc-5921	233	60	-	-	PUNCT
dpc-5921	233	61	to	to	ADP
dpc-5921	233	62	-	-	PUNCT
dpc-5921	233	63	treat	treat	VERB
dpc-5921	233	64	lesions	lesion	NOUN
dpc-5921	233	65	,	,	PUNCT
dpc-5921	233	66	comorbid	comorbid	NOUN
dpc-5921	233	67	conditions	condition	NOUN
dpc-5921	233	68	,	,	PUNCT
dpc-5921	233	69	or	or	CCONJ
dpc-5921	233	70	a	a	DET
dpc-5921	233	71	history	history	NOUN
dpc-5921	233	72	of	of	ADP
dpc-5921	233	73	previous	previous	ADJ
dpc-5921	233	74	skin	skin	NOUN
dpc-5921	233	75	cancer	cancer	NOUN
dpc-5921	233	76	.	.	PUNCT
dpc-5921	234	1	flexible	flexible	ADJ
dpc-5921	234	2	therapeutic	therapeutic	ADJ
dpc-5921	234	3	protocols	protocol	NOUN
dpc-5921	234	4	with	with	ADP
dpc-5921	234	5	repeated	repeat	VERB
dpc-5921	234	6	treatment	treatment	NOUN
dpc-5921	234	7	cycles	cycle	NOUN
dpc-5921	234	8	are	be	AUX
dpc-5921	234	9	made	make	VERB
dpc-5921	234	10	possible	possible	ADJ
dpc-5921	234	11	by	by	ADP
dpc-5921	234	12	the	the	DET
dpc-5921	234	13	10	10	NUM
dpc-5921	234	14	review	review	NOUN
dpc-5921	234	15	|	|	ADV
dpc-5921	234	16	dermatol	dermatol	ADJ
dpc-5921	234	17	pract	pract	NOUN
dpc-5921	234	18	concept	concept	NOUN
dpc-5921	234	19	.	.	PUNCT
dpc-5921	235	1	2025;15(3):5921	2025;15(3):5921	NUM
dpc-5921	235	2	24	24	NUM
dpc-5921	235	3	.	.	PUNCT
dpc-5921	236	1	lacarrubba	lacarrubba	PROPN
dpc-5921	236	2	f	f	PROPN
dpc-5921	236	3	,	,	PUNCT
dpc-5921	236	4	verzì	verzì	NOUN
dpc-5921	236	5	ae	ae	PROPN
dpc-5921	236	6	,	,	PUNCT
dpc-5921	236	7	polita	polita	PROPN
dpc-5921	236	8	m	m	PROPN
dpc-5921	236	9	,	,	PUNCT
dpc-5921	236	10	aleo	aleo	ADV
dpc-5921	236	11	a	a	DET
dpc-5921	236	12	,	,	PUNCT
dpc-5921	236	13	micali	micali	PROPN
dpc-5921	236	14	g.	g.	PROPN
dpc-5921	236	15	line	line	NOUN
dpc-5921	236	16	-	-	PUNCT
dpc-5921	236	17	field	field	NOUN
dpc-5921	236	18	confocal	confocal	ADJ
dpc-5921	236	19	optical	optical	ADJ
dpc-5921	236	20	coherence	coherence	NOUN
dpc-5921	236	21	tomography	tomography	NOUN
dpc-5921	236	22	in	in	ADP
dpc-5921	236	23	the	the	DET
dpc-5921	236	24	treatment	treatment	NOUN
dpc-5921	236	25	monitoring	monitoring	NOUN
dpc-5921	236	26	of	of	ADP
dpc-5921	236	27	actinic	actinic	ADJ
dpc-5921	236	28	keratosis	keratosis	NOUN
dpc-5921	236	29	with	with	ADP
dpc-5921	236	30	tirbanibulin	tirbanibulin	PROPN
dpc-5921	236	31	:	:	PUNCT
dpc-5921	236	32	a	a	DET
dpc-5921	236	33	pilot	pilot	NOUN
dpc-5921	236	34	study	study	NOUN
dpc-5921	236	35	.	.	PUNCT
dpc-5921	237	1	j	j	PROPN
dpc-5921	237	2	eur	eur	PROPN
dpc-5921	237	3	acad	acad	PROPN
dpc-5921	237	4	dermatol	dermatol	NOUN
dpc-5921	237	5	venereol	venereol	NOUN
dpc-5921	237	6	.	.	PUNCT
dpc-5921	238	1	2023;37(9):e1131	2023;37(9):e1131	X
dpc-5921	238	2	-	-	PUNCT
dpc-5921	238	3	e1133	e1133	NOUN
dpc-5921	238	4	.	.	PUNCT
dpc-5921	239	1	doi	doi	NOUN
dpc-5921	239	2	:	:	PUNCT
dpc-5921	239	3	10.1111	10.1111	NUM
dpc-5921	239	4	/	/	SYM
dpc-5921	239	5	jdv.19147	jdv.19147	PROPN
dpc-5921	239	6	.	.	PUNCT
dpc-5921	240	1	pmid	pmid	NOUN
dpc-5921	240	2	:	:	PUNCT
dpc-5921	240	3	37102431	37102431	NUM
dpc-5921	240	4	.	.	PUNCT
dpc-5921	241	1	25	25	NUM
dpc-5921	241	2	.	.	PUNCT
dpc-5921	242	1	venturi	venturi	PROPN
dpc-5921	242	2	f	f	PROPN
dpc-5921	242	3	,	,	PUNCT
dpc-5921	242	4	veronesi	veronesi	NOUN
dpc-5921	242	5	g	g	PROPN
dpc-5921	242	6	,	,	PUNCT
dpc-5921	242	7	baraldi	baraldi	NOUN
dpc-5921	242	8	c	c	AUX
dpc-5921	242	9	,	,	PUNCT
dpc-5921	242	10	dika	dika	X
dpc-5921	242	11	e.	e.	PROPN
dpc-5921	242	12	reflectance	reflectance	PROPN
dpc-5921	242	13	confocal	confocal	ADJ
dpc-5921	242	14	microscopy	microscopy	NOUN
dpc-5921	242	15	as	as	ADP
dpc-5921	242	16	noninvasive	noninvasive	ADJ
dpc-5921	242	17	tool	tool	NOUN
dpc-5921	242	18	for	for	ADP
dpc-5921	242	19	monitoring	monitor	VERB
dpc-5921	242	20	tirbanibulin	tirbanibulin	PROPN
dpc-5921	242	21	efficacy	efficacy	NOUN
dpc-5921	242	22	in	in	ADP
dpc-5921	242	23	actinic	actinic	ADJ
dpc-5921	242	24	keratosis	keratosis	NOUN
dpc-5921	242	25	.	.	PUNCT
dpc-5921	243	1	photodiagnosis	photodiagnosis	NOUN
dpc-5921	243	2	photodyn	photodyn	NOUN
dpc-5921	243	3	ther	ther	ADV
dpc-5921	243	4	.	.	PUNCT
dpc-5921	244	1	2024;48:104235	2024;48:104235	X
dpc-5921	244	2	.	.	PUNCT
dpc-5921	244	3	doi	doi	NOUN
dpc-5921	244	4	:	:	PUNCT
dpc-5921	244	5	10.1016	10.1016	NUM
dpc-5921	244	6	/	/	SYM
dpc-5921	244	7	j.pdpdt.2024.104235	j.pdpdt.2024.104235	ADJ
dpc-5921	244	8	.	.	PUNCT
dpc-5921	245	1	pmid	pmid	NOUN
dpc-5921	245	2	:	:	PUNCT
dpc-5921	245	3	38851311	38851311	NUM
dpc-5921	245	4	.	.	PUNCT
dpc-5921	246	1	26	26	NUM
dpc-5921	246	2	.	.	PUNCT
dpc-5921	247	1	morton	morton	PROPN
dpc-5921	247	2	c	c	PROPN
dpc-5921	247	3	,	,	PUNCT
dpc-5921	247	4	baharlou	baharlou	PROPN
dpc-5921	247	5	s	s	PROPN
dpc-5921	247	6	,	,	PUNCT
dpc-5921	247	7	basset	basset	NOUN
dpc-5921	247	8	-	-	PUNCT
dpc-5921	247	9	seguin	seguin	NOUN
dpc-5921	247	10	n	n	CCONJ
dpc-5921	247	11	,	,	PUNCT
dpc-5921	247	12	et	et	PROPN
dpc-5921	247	13	al	al	PROPN
dpc-5921	247	14	.	.	PUNCT
dpc-5921	248	1	expert	expert	ADJ
dpc-5921	248	2	recommendations	recommendation	NOUN
dpc-5921	248	3	on	on	ADP
dpc-5921	248	4	facilitating	facilitate	VERB
dpc-5921	248	5	personalized	personalized	ADJ
dpc-5921	248	6	approaches	approach	NOUN
dpc-5921	248	7	to	to	AUX
dpc-5921	248	8	longterm	longterm	VERB
dpc-5921	248	9	management	management	NOUN
dpc-5921	248	10	of	of	ADP
dpc-5921	248	11	actinic	actinic	ADJ
dpc-5921	248	12	keratosis	keratosis	NOUN
dpc-5921	248	13	:	:	PUNCT
dpc-5921	248	14	the	the	DET
dpc-5921	248	15	personalizing	personalize	VERB
dpc-5921	248	16	actinic	actinic	ADJ
dpc-5921	248	17	keratosis	keratosis	NOUN
dpc-5921	248	18	treatment	treatment	NOUN
dpc-5921	248	19	(	(	PUNCT
dpc-5921	248	20	pakt	pakt	NOUN
dpc-5921	248	21	)	)	PUNCT
dpc-5921	248	22	project	project	NOUN
dpc-5921	248	23	.	.	PUNCT
dpc-5921	249	1	acta	acta	PROPN
dpc-5921	249	2	derm	derm	PROPN
dpc-5921	249	3	venereol	venereol	NOUN
dpc-5921	249	4	.	.	PUNCT
dpc-5921	250	1	2023;103	2023;103	NUM
dpc-5921	250	2	:	:	PUNCT
dpc-5921	250	3	adv6229	adv6229	NOUN
dpc-5921	250	4	.	.	PUNCT
dpc-5921	251	1	doi	doi	NOUN
dpc-5921	251	2	:	:	PUNCT
dpc-5921	251	3	10.2340	10.2340	NUM
dpc-5921	251	4	/	/	SYM
dpc-5921	251	5	actadv.v103.6229	actadv.v103.6229	NOUN
dpc-5921	251	6	.	.	PUNCT
dpc-5921	252	1	pmid	pmid	NOUN
dpc-5921	252	2	:	:	PUNCT
dpc-5921	252	3	37289027	37289027	NUM
dpc-5921	252	4	.	.	PUNCT
dpc-5921	253	1	27	27	NUM
dpc-5921	253	2	.	.	X
dpc-5921	253	3	de	de	PROPN
dpc-5921	253	4	berker	berker	PROPN
dpc-5921	253	5	d	d	PROPN
dpc-5921	253	6	,	,	PUNCT
dpc-5921	253	7	mcgregor	mcgregor	PROPN
dpc-5921	253	8	jm	jm	PROPN
dpc-5921	253	9	,	,	PUNCT
dpc-5921	253	10	mohd	mohd	PROPN
dpc-5921	253	11	mustapa	mustapa	PROPN
dpc-5921	253	12	mf	mf	PROPN
dpc-5921	253	13	,	,	PUNCT
dpc-5921	253	14	exton	exton	PROPN
dpc-5921	253	15	ls	ls	PROPN
dpc-5921	253	16	,	,	PUNCT
dpc-5921	253	17	hughes	hughes	PROPN
dpc-5921	253	18	br	br	PROPN
dpc-5921	253	19	.	.	PUNCT
dpc-5921	254	1	british	british	PROPN
dpc-5921	254	2	association	association	PROPN
dpc-5921	254	3	of	of	ADP
dpc-5921	254	4	dermatologists	dermatologist	NOUN
dpc-5921	254	5	’	'	PUNCT
dpc-5921	254	6	guidelines	guideline	NOUN
dpc-5921	254	7	for	for	ADP
dpc-5921	254	8	the	the	DET
dpc-5921	254	9	care	care	NOUN
dpc-5921	254	10	of	of	ADP
dpc-5921	254	11	patients	patient	NOUN
dpc-5921	254	12	with	with	ADP
dpc-5921	254	13	actinic	actinic	ADJ
dpc-5921	254	14	keratosis	keratosis	NOUN
dpc-5921	254	15	2017	2017	NUM
dpc-5921	254	16	.	.	PUNCT
dpc-5921	255	1	br	br	PROPN
dpc-5921	255	2	j	j	PROPN
dpc-5921	255	3	dermatol	dermatol	NOUN
dpc-5921	255	4	.	.	PUNCT
dpc-5921	256	1	2017;176(1):20	2017;176(1):20	NUM
dpc-5921	256	2	-	-	SYM
dpc-5921	256	3	43	43	NUM
dpc-5921	256	4	.	.	PUNCT
dpc-5921	257	1	doi	doi	NOUN
dpc-5921	257	2	:	:	PUNCT
dpc-5921	257	3	10.1111	10.1111	NUM
dpc-5921	257	4	/	/	SYM
dpc-5921	257	5	bjd.15107	bjd.15107	PROPN
dpc-5921	257	6	.	.	PUNCT
dpc-5921	258	1	pmid	pmid	NOUN
dpc-5921	258	2	:	:	PUNCT
dpc-5921	258	3	28098380	28098380	NUM
dpc-5921	258	4	.	.	PUNCT
dpc-5921	259	1	28	28	NUM
dpc-5921	259	2	.	.	X
dpc-5921	260	1	ahmady	ahmady	PROPN
dpc-5921	260	2	s	s	PROPN
dpc-5921	260	3	,	,	PUNCT
dpc-5921	260	4	jansen	jansen	PROPN
dpc-5921	260	5	mhe	mhe	PROPN
dpc-5921	260	6	,	,	PUNCT
dpc-5921	260	7	nelemans	nelemans	PROPN
dpc-5921	260	8	pj	pj	PROPN
dpc-5921	260	9	,	,	PUNCT
dpc-5921	260	10	et	et	PROPN
dpc-5921	260	11	al	al	PROPN
dpc-5921	260	12	.	.	PROPN
dpc-5921	261	1	risk	risk	NOUN
dpc-5921	261	2	of	of	ADP
dpc-5921	261	3	invasive	invasive	ADJ
dpc-5921	261	4	cutaneous	cutaneous	ADJ
dpc-5921	261	5	squamous	squamous	ADJ
dpc-5921	261	6	cell	cell	NOUN
dpc-5921	261	7	carcinoma	carcinoma	NOUN
dpc-5921	261	8	after	after	ADP
dpc-5921	261	9	different	different	ADJ
dpc-5921	261	10	treatments	treatment	NOUN
dpc-5921	261	11	for	for	ADP
dpc-5921	261	12	actinic	actinic	ADJ
dpc-5921	261	13	keratosis	keratosis	NOUN
dpc-5921	261	14	:	:	PUNCT
dpc-5921	261	15	a	a	DET
dpc-5921	261	16	secondary	secondary	ADJ
dpc-5921	261	17	analysis	analysis	NOUN
dpc-5921	261	18	of	of	ADP
dpc-5921	261	19	a	a	DET
dpc-5921	261	20	randomized	randomized	ADJ
dpc-5921	261	21	clinical	clinical	ADJ
dpc-5921	261	22	trial	trial	NOUN
dpc-5921	261	23	.	.	PUNCT
dpc-5921	262	1	jama	jama	PROPN
dpc-5921	262	2	dermatol	dermatol	NOUN
dpc-5921	262	3	.	.	PUNCT
dpc-5921	263	1	2022;158(6):634	2022;158(6):634	NUM
dpc-5921	263	2	-	-	NOUN
dpc-5921	263	3	640	640	NUM
dpc-5921	263	4	.	.	PUNCT
dpc-5921	264	1	doi	doi	NOUN
dpc-5921	264	2	:	:	PUNCT
dpc-5921	264	3	10.1001	10.1001	NUM
dpc-5921	264	4	/	/	SYM
dpc-5921	264	5	jamadermatol.2022.1034	jamadermatol.2022.1034	NOUN
dpc-5921	264	6	.	.	PUNCT
dpc-5921	265	1	pmid	pmid	NOUN
dpc-5921	265	2	:	:	PUNCT
dpc-5921	265	3	35475852	35475852	NUM
dpc-5921	265	4	.	.	PUNCT
dpc-5921	266	1	29	29	NUM
dpc-5921	266	2	.	.	PUNCT
dpc-5921	267	1	neugebauer	neugebauer	PROPN
dpc-5921	267	2	r	r	NOUN
dpc-5921	267	3	,	,	PUNCT
dpc-5921	267	4	su	su	PROPN
dpc-5921	267	5	ka	ka	PROPN
dpc-5921	267	6	,	,	PUNCT
dpc-5921	267	7	zhu	zhu	PROPN
dpc-5921	268	1	z	z	X
dpc-5921	268	2	,	,	PUNCT
dpc-5921	268	3	et	et	PROPN
dpc-5921	268	4	al	al	PROPN
dpc-5921	268	5	.	.	PROPN
dpc-5921	268	6	comparative	comparative	ADJ
dpc-5921	268	7	effectiveness	effectiveness	NOUN
dpc-5921	268	8	of	of	ADP
dpc-5921	268	9	treatment	treatment	NOUN
dpc-5921	268	10	of	of	ADP
dpc-5921	268	11	actinic	actinic	ADJ
dpc-5921	268	12	keratosis	keratosis	NOUN
dpc-5921	268	13	with	with	ADP
dpc-5921	268	14	topical	topical	ADJ
dpc-5921	268	15	fluorouracil	fluorouracil	NOUN
dpc-5921	268	16	and	and	CCONJ
dpc-5921	268	17	imiquimod	imiquimod	PROPN
dpc-5921	268	18	in	in	ADP
dpc-5921	268	19	the	the	DET
dpc-5921	268	20	prevention	prevention	NOUN
dpc-5921	268	21	of	of	ADP
dpc-5921	268	22	keratinocyte	keratinocyte	NOUN
dpc-5921	268	23	carcinoma	carcinoma	NOUN
dpc-5921	268	24	:	:	PUNCT
dpc-5921	268	25	a	a	DET
dpc-5921	268	26	  	  	SPACE
dpc-5921	268	27	cohort	cohort	NOUN
dpc-5921	268	28	study	study	NOUN
dpc-5921	268	29	.	.	PUNCT
dpc-5921	269	1	j	j	PROPN
dpc-5921	269	2	am	be	AUX
dpc-5921	269	3	acad	acad	ADJ
dpc-5921	269	4	dermatol	dermatol	NOUN
dpc-5921	269	5	.	.	PUNCT
dpc-5921	270	1	2019;80(4):998	2019;80(4):998	NUM
dpc-5921	270	2	-	-	PROPN
dpc-5921	270	3	1005	1005	NUM
dpc-5921	270	4	.	.	PUNCT
dpc-5921	271	1	doi	doi	NOUN
dpc-5921	271	2	:	:	PUNCT
dpc-5921	271	3	10.1016	10.1016	NUM
dpc-5921	271	4	/	/	SYM
dpc-5921	271	5	j.jaad.2018.11.024	j.jaad.2018.11.024	PROPN
dpc-5921	271	6	.	.	PUNCT
dpc-5921	272	1	pmid	pmid	NOUN
dpc-5921	272	2	:	:	PUNCT
dpc-5921	272	3	30458208	30458208	NUM
dpc-5921	272	4	.	.	PUNCT
dpc-5921	273	1	30	30	NUM
dpc-5921	273	2	.	.	PUNCT
dpc-5921	273	3	pellacani	pellacani	PROPN
dpc-5921	273	4	g	g	PROPN
dpc-5921	273	5	,	,	PUNCT
dpc-5921	273	6	schlesinger	schlesinger	PROPN
dpc-5921	273	7	t	t	PROPN
dpc-5921	273	8	,	,	PUNCT
dpc-5921	273	9	bhatia	bhatia	PROPN
dpc-5921	273	10	n	n	PRON
dpc-5921	273	11	,	,	PUNCT
dpc-5921	273	12	et	et	PROPN
dpc-5921	273	13	al	al	PROPN
dpc-5921	273	14	.	.	PROPN
dpc-5921	273	15	efficacy	efficacy	NOUN
dpc-5921	273	16	and	and	CCONJ
dpc-5921	273	17	safety	safety	NOUN
dpc-5921	273	18	of	of	ADP
dpc-5921	273	19	tirbanibulin	tirbanibulin	DET
dpc-5921	273	20	1	1	NUM
dpc-5921	273	21	%	%	NOUN
dpc-5921	273	22	ointment	ointment	NOUN
dpc-5921	273	23	in	in	ADP
dpc-5921	273	24	actinic	actinic	ADJ
dpc-5921	273	25	keratoses	keratose	NOUN
dpc-5921	273	26	:	:	PUNCT
dpc-5921	273	27	data	datum	NOUN
dpc-5921	273	28	from	from	ADP
dpc-5921	273	29	two	two	NUM
dpc-5921	273	30	phase	phase	NOUN
dpc-5921	273	31	-	-	PUNCT
dpc-5921	273	32	iii	iii	NOUN
dpc-5921	273	33	trials	trial	NOUN
dpc-5921	273	34	and	and	CCONJ
dpc-5921	273	35	the	the	DET
dpc-5921	273	36	real	real	ADJ
dpc-5921	273	37	-	-	PUNCT
dpc-5921	273	38	life	life	NOUN
dpc-5921	273	39	clinical	clinical	ADJ
dpc-5921	273	40	practice	practice	NOUN
dpc-5921	273	41	presented	present	VERB
dpc-5921	273	42	at	at	ADP
dpc-5921	273	43	the	the	DET
dpc-5921	273	44	european	european	PROPN
dpc-5921	273	45	academy	academy	PROPN
dpc-5921	273	46	of	of	ADP
dpc-5921	273	47	dermatology	dermatology	NOUN
dpc-5921	273	48	and	and	CCONJ
dpc-5921	273	49	venereology	venereology	NOUN
dpc-5921	273	50	congress	congress	PROPN
dpc-5921	273	51	2022	2022	NUM
dpc-5921	273	52	.	.	PUNCT
dpc-5921	274	1	j	j	PROPN
dpc-5921	274	2	eur	eur	PROPN
dpc-5921	274	3	acad	acad	PROPN
dpc-5921	274	4	dermatol	dermatol	NOUN
dpc-5921	274	5	venereol	venereol	NOUN
dpc-5921	274	6	.	.	PUNCT
dpc-5921	275	1	2024;38	2024;38	NUM
dpc-5921	275	2	suppl	suppl	NOUN
dpc-5921	275	3	1:3	1:3	NUM
dpc-5921	275	4	-	-	SYM
dpc-5921	275	5	15	15	NUM
dpc-5921	275	6	.	.	PUNCT
dpc-5921	275	7	doi	doi	NOUN
dpc-5921	275	8	:	:	PUNCT
dpc-5921	275	9	10.1111	10.1111	NUM
dpc-5921	275	10	/	/	SYM
dpc-5921	275	11	jdv.19636	jdv.19636	NOUN
dpc-5921	275	12	.	.	PUNCT
dpc-5921	276	1	pmid	pmid	NOUN
dpc-5921	276	2	:	:	PUNCT
dpc-5921	276	3	38116638	38116638	NUM
dpc-5921	276	4	.	.	PUNCT
dpc-5921	277	1	31	31	NUM
dpc-5921	277	2	.	.	PUNCT
dpc-5921	278	1	iglesias	iglesias	PROPN
dpc-5921	278	2	-	-	PUNCT
dpc-5921	278	3	puzas	puza	NOUN
dpc-5921	278	4	á	á	PROPN
dpc-5921	278	5	,	,	PUNCT
dpc-5921	278	6	conde	conde	PROPN
dpc-5921	278	7	-	-	PUNCT
dpc-5921	278	8	taboada	taboada	PROPN
dpc-5921	278	9	a	a	PROPN
dpc-5921	278	10	,	,	PUNCT
dpc-5921	278	11	campos	campos	PROPN
dpc-5921	278	12	-	-	PUNCT
dpc-5921	278	13	muñoz	muñoz	PROPN
dpc-5921	278	14	l	l	PROPN
dpc-5921	278	15	,	,	PUNCT
dpc-5921	278	16	sirgado	sirgado	NOUN
dpc-5921	278	17	-	-	PUNCT
dpc-5921	278	18	martínez	martínez	PROPN
dpc-5921	278	19	a	a	PROPN
dpc-5921	278	20	,	,	PUNCT
dpc-5921	278	21	lópez	lópez	NOUN
dpc-5921	278	22	-	-	PUNCT
dpc-5921	278	23	bran	bran	NOUN
dpc-5921	278	24	e.	e.	PROPN
dpc-5921	278	25	1	1	NUM
dpc-5921	278	26	%	%	NOUN
dpc-5921	278	27	tirbanibulin	tirbanibulin	PROPN
dpc-5921	278	28	ointment	ointment	NOUN
dpc-5921	278	29	for	for	ADP
dpc-5921	278	30	actinic	actinic	ADJ
dpc-5921	278	31	keratoses	keratose	NOUN
dpc-5921	278	32	on	on	ADP
dpc-5921	278	33	upper	upper	ADJ
dpc-5921	278	34	extremities	extremity	NOUN
dpc-5921	278	35	:	:	PUNCT
dpc-5921	278	36	a	a	DET
dpc-5921	278	37	retrospective	retrospective	ADJ
dpc-5921	278	38	case	case	NOUN
dpc-5921	278	39	review	review	NOUN
dpc-5921	278	40	study	study	NOUN
dpc-5921	278	41	.	.	PUNCT
dpc-5921	279	1	acta	acta	PROPN
dpc-5921	279	2	derm	derm	PROPN
dpc-5921	279	3	venereol	venereol	NOUN
dpc-5921	279	4	.	.	PUNCT
dpc-5921	280	1	2023;103	2023;103	NUM
dpc-5921	280	2	:	:	PUNCT
dpc-5921	280	3	adv15296	adv15296	NOUN
dpc-5921	280	4	.	.	PUNCT
dpc-5921	281	1	doi	doi	NOUN
dpc-5921	281	2	:	:	PUNCT
dpc-5921	281	3	10.2340	10.2340	NUM
dpc-5921	281	4	/	/	SYM
dpc-5921	281	5	actadv.v103.15296	actadv.v103.15296	NOUN
dpc-5921	281	6	.	.	PUNCT
dpc-5921	282	1	pmid	pmid	NOUN
dpc-5921	282	2	:	:	PUNCT
dpc-5921	282	3	37876333	37876333	NUM
dpc-5921	282	4	.	.	PUNCT
dpc-5921	283	1	32	32	NUM
dpc-5921	283	2	.	.	PUNCT
dpc-5921	284	1	schlesinger	schlesinger	PROPN
dpc-5921	284	2	t.	t.	PROPN
dpc-5921	284	3	commentary	commentary	PROPN
dpc-5921	284	4	:	:	PUNCT
dpc-5921	284	5	impact	impact	NOUN
dpc-5921	284	6	of	of	ADP
dpc-5921	284	7	prior	prior	ADJ
dpc-5921	284	8	treatment	treatment	NOUN
dpc-5921	284	9	in	in	ADP
dpc-5921	284	10	the	the	DET
dpc-5921	284	11	efficacy	efficacy	NOUN
dpc-5921	284	12	and	and	CCONJ
dpc-5921	284	13	tolerability	tolerability	NOUN
dpc-5921	284	14	of	of	ADP
dpc-5921	284	15	tirbanibulin	tirbanibulin	PROPN
dpc-5921	284	16	ointment	ointment	NOUN
dpc-5921	284	17	1	1	NUM
dpc-5921	284	18	%	%	NOUN
dpc-5921	284	19	for	for	ADP
dpc-5921	284	20	actinic	actinic	ADJ
dpc-5921	284	21	keratosis	keratosis	NOUN
dpc-5921	284	22	:	:	PUNCT
dpc-5921	284	23	pooled	pool	VERB
dpc-5921	284	24	results	result	NOUN
dpc-5921	284	25	from	from	ADP
dpc-5921	284	26	two	two	NUM
dpc-5921	284	27	phase	phase	NOUN
dpc-5921	284	28	iii	iii	NUM
dpc-5921	284	29	studies	study	NOUN
dpc-5921	284	30	.	.	PUNCT
dpc-5921	285	1	j	j	PROPN
dpc-5921	285	2	clin	clin	PROPN
dpc-5921	285	3	aesthet	aesthet	PROPN
dpc-5921	285	4	dermatol	dermatol	PROPN
dpc-5921	285	5	.	.	PUNCT
dpc-5921	286	1	2022;15(10	2022;15(10	NUM
dpc-5921	286	2	suppl	suppl	ADJ
dpc-5921	286	3	1):s11	1):s11	NUM
dpc-5921	286	4	-	-	PUNCT
dpc-5921	286	5	s12	s12	NOUN
dpc-5921	286	6	.	.	PUNCT
dpc-5921	287	1	pmid	pmid	NOUN
dpc-5921	287	2	:	:	PUNCT
dpc-5921	287	3	36408373	36408373	NUM
dpc-5921	287	4	.	.	PUNCT
dpc-5921	288	1	33	33	NUM
dpc-5921	288	2	.	.	PUNCT
dpc-5921	288	3	smolinski	smolinski	PROPN
dpc-5921	288	4	mp	mp	PROPN
dpc-5921	288	5	,	,	PUNCT
dpc-5921	288	6	bu	bu	PROPN
dpc-5921	288	7	y	y	PROPN
dpc-5921	288	8	,	,	PUNCT
dpc-5921	288	9	clements	clements	PROPN
dpc-5921	288	10	j	j	PROPN
dpc-5921	288	11	,	,	PUNCT
dpc-5921	288	12	et	et	PROPN
dpc-5921	288	13	al	al	PROPN
dpc-5921	288	14	.	.	PROPN
dpc-5921	288	15	discovery	discovery	PROPN
dpc-5921	288	16	of	of	ADP
dpc-5921	288	17	novel	novel	ADJ
dpc-5921	288	18	dual	dual	ADJ
dpc-5921	288	19	mechanism	mechanism	NOUN
dpc-5921	288	20	of	of	ADP
dpc-5921	288	21	action	action	NOUN
dpc-5921	288	22	src	src	NOUN
dpc-5921	288	23	signaling	signal	VERB
dpc-5921	288	24	and	and	CCONJ
dpc-5921	288	25	tubulin	tubulin	NOUN
dpc-5921	288	26	polymerization	polymerization	NOUN
dpc-5921	288	27	inhibitors	inhibitor	NOUN
dpc-5921	288	28	(	(	PUNCT
dpc-5921	288	29	kx2	kx2	PROPN
dpc-5921	288	30	-	-	X
dpc-5921	288	31	391	391	NUM
dpc-5921	288	32	and	and	CCONJ
dpc-5921	288	33	kx2	kx2	PROPN
dpc-5921	288	34	-	-	PUNCT
dpc-5921	288	35	361	361	NUM
dpc-5921	288	36	)	)	PUNCT
dpc-5921	288	37	.	.	PUNCT
dpc-5921	289	1	j	j	PROPN
dpc-5921	289	2	med	med	PROPN
dpc-5921	289	3	chem	chem	NOUN
dpc-5921	289	4	.	.	PUNCT
dpc-5921	290	1	2018;61(11):4704	2018;61(11):4704	NUM
dpc-5921	290	2	-	-	SYM
dpc-5921	290	3	4719	4719	NUM
dpc-5921	290	4	.	.	PUNCT
dpc-5921	291	1	doi	doi	NOUN
dpc-5921	291	2	:	:	PUNCT
dpc-5921	291	3	10.1021	10.1021	NUM
dpc-5921	291	4	/	/	SYM
dpc-5921	291	5	acs.jmedchem.8b00164	acs.jmedchem.8b00164	NOUN
dpc-5921	291	6	.	.	PUNCT
dpc-5921	292	1	pmid	pmid	NOUN
dpc-5921	292	2	:	:	PUNCT
dpc-5921	292	3	29617135	29617135	NUM
dpc-5921	292	4	.	.	PUNCT
dpc-5921	293	1	34	34	NUM
dpc-5921	293	2	.	.	PUNCT
dpc-5921	294	1	niu	niu	PROPN
dpc-5921	294	2	l	l	PROPN
dpc-5921	294	3	,	,	PUNCT
dpc-5921	294	4	yang	yang	PROPN
dpc-5921	294	5	j	j	PROPN
dpc-5921	294	6	,	,	PUNCT
dpc-5921	294	7	yan	yan	PROPN
dpc-5921	294	8	w	w	PROPN
dpc-5921	294	9	,	,	PUNCT
dpc-5921	294	10	et	et	PROPN
dpc-5921	294	11	al	al	PROPN
dpc-5921	294	12	.	.	PUNCT
dpc-5921	295	1	reversible	reversible	ADJ
dpc-5921	295	2	binding	binding	NOUN
dpc-5921	295	3	of	of	ADP
dpc-5921	295	4	the	the	DET
dpc-5921	295	5	anticancer	anticancer	NOUN
dpc-5921	295	6	drug	drug	NOUN
dpc-5921	295	7	kxo1	kxo1	PROPN
dpc-5921	295	8	(	(	PUNCT
dpc-5921	295	9	tirbanibulin	tirbanibulin	PROPN
dpc-5921	295	10	)	)	PUNCT
dpc-5921	295	11	to	to	ADP
dpc-5921	295	12	the	the	DET
dpc-5921	295	13	colchicine	colchicine	NOUN
dpc-5921	295	14	-	-	PUNCT
dpc-5921	295	15	binding	bind	VERB
dpc-5921	295	16	site	site	NOUN
dpc-5921	295	17	of	of	ADP
dpc-5921	295	18	β	β	NOUN
dpc-5921	295	19	-	-	PUNCT
dpc-5921	295	20	tubulin	tubulin	NOUN
dpc-5921	295	21	explains	explain	VERB
dpc-5921	295	22	kxo1	kxo1	PROPN
dpc-5921	295	23	’s	’s	PART
dpc-5921	295	24	low	low	ADJ
dpc-5921	295	25	clinical	clinical	ADJ
dpc-5921	295	26	toxicity	toxicity	NOUN
dpc-5921	295	27	.	.	PUNCT
dpc-5921	296	1	j	j	PROPN
dpc-5921	296	2	biol	biol	PROPN
dpc-5921	296	3	chem	chem	NOUN
dpc-5921	296	4	.	.	PUNCT
dpc-5921	297	1	2019;294(48):18099	2019;294(48):18099	NUM
dpc-5921	297	2	-	-	SYM
dpc-5921	297	3	18108	18108	NUM
dpc-5921	297	4	.	.	PUNCT
dpc-5921	298	1	doi	doi	NOUN
dpc-5921	298	2	:	:	PUNCT
dpc-5921	298	3	10.1074	10.1074	NUM
dpc-5921	298	4	/	/	SYM
dpc-5921	298	5	jbc.ra119.010732	jbc.ra119.010732	NOUN
dpc-5921	298	6	.	.	PUNCT
dpc-5921	299	1	pmid	pmid	NOUN
dpc-5921	299	2	:	:	PUNCT
dpc-5921	299	3	31628188	31628188	NUM
dpc-5921	299	4	.	.	PUNCT
dpc-5921	300	1	35	35	NUM
dpc-5921	300	2	.	.	PUNCT
dpc-5921	301	1	lacarrubba	lacarrubba	PROPN
dpc-5921	301	2	f	f	PROPN
dpc-5921	301	3	,	,	PUNCT
dpc-5921	301	4	verzì	verzì	NOUN
dpc-5921	301	5	ae	ae	PROPN
dpc-5921	301	6	,	,	PUNCT
dpc-5921	301	7	broggi	broggi	VERB
dpc-5921	301	8	g	g	NOUN
dpc-5921	301	9	,	,	PUNCT
dpc-5921	301	10	micali	micali	PROPN
dpc-5921	301	11	g.	g.	PROPN
dpc-5921	301	12	line	line	NOUN
dpc-5921	301	13	-	-	PUNCT
dpc-5921	301	14	field	field	NOUN
dpc-5921	301	15	confocal	confocal	ADJ
dpc-5921	301	16	optical	optical	ADJ
dpc-5921	301	17	coherence	coherence	NOUN
dpc-5921	301	18	tomography	tomography	NOUN
dpc-5921	301	19	shows	show	NOUN
dpc-5921	301	20	in	in	ADP
dpc-5921	301	21	vivo	vivo	ADJ
dpc-5921	301	22	apoptosis	apoptosis	NOUN
dpc-5921	301	23	during	during	ADP
dpc-5921	301	24	a	a	DET
dpc-5921	301	25	novel	novel	ADJ
dpc-5921	301	26	treatment	treatment	NOUN
dpc-5921	301	27	for	for	ADP
dpc-5921	301	28	actinic	actinic	ADJ
dpc-5921	301	29	keratosis	keratosis	NOUN
dpc-5921	301	30	:	:	PUNCT
dpc-5921	301	31	a	a	DET
dpc-5921	301	32	histopathologic	histopathologic	NOUN
dpc-5921	301	33	controlled	control	VERB
dpc-5921	301	34	study	study	NOUN
dpc-5921	301	35	.	.	PUNCT
dpc-5921	302	1	j	j	PROPN
dpc-5921	302	2	eur	eur	PROPN
dpc-5921	302	3	acad	acad	PROPN
dpc-5921	302	4	dermatol	dermatol	NOUN
dpc-5921	302	5	venereol	venereol	NOUN
dpc-5921	302	6	.	.	PUNCT
dpc-5921	303	1	2025;39(1):e60	2025;39(1):e60	X
dpc-5921	303	2	-	-	PUNCT
dpc-5921	303	3	e62	e62	NOUN
dpc-5921	303	4	.	.	PUNCT
dpc-5921	304	1	doi	doi	NOUN
dpc-5921	304	2	:	:	PUNCT
dpc-5921	304	3	10.1111	10.1111	NUM
dpc-5921	304	4	/	/	SYM
dpc-5921	304	5	jdv.20106	jdv.20106	NOUN
dpc-5921	304	6	.	.	PUNCT
dpc-5921	305	1	pmid	pmid	NOUN
dpc-5921	305	2	:	:	PUNCT
dpc-5921	305	3	38752705	38752705	NUM
dpc-5921	305	4	.	.	PUNCT
dpc-5921	306	1	11	11	NUM
dpc-5921	306	2	.	.	X
dpc-5921	306	3	kirchberger	kirchberger	PROPN
dpc-5921	306	4	mc	mc	PROPN
dpc-5921	306	5	,	,	PUNCT
dpc-5921	306	6	gfesser	gfesser	PROPN
dpc-5921	306	7	m	m	PROPN
dpc-5921	306	8	,	,	PUNCT
dpc-5921	306	9	erdmann	erdmann	PROPN
dpc-5921	306	10	m	m	PROPN
dpc-5921	306	11	,	,	PUNCT
dpc-5921	306	12	schliep	schliep	PROPN
dpc-5921	306	13	s	s	NOUN
dpc-5921	306	14	,	,	PUNCT
dpc-5921	306	15	berking	berke	VERB
dpc-5921	306	16	c	c	NOUN
dpc-5921	306	17	,	,	PUNCT
dpc-5921	306	18	heppt	heppt	ADJ
dpc-5921	306	19	mv	mv	PROPN
dpc-5921	306	20	.	.	PROPN
dpc-5921	307	1	tirbanibulin	tirbanibulin	PROPN
dpc-5921	307	2	1	1	NUM
dpc-5921	307	3	%	%	NOUN
dpc-5921	307	4	ointment	ointment	NOUN
dpc-5921	307	5	significantly	significantly	ADV
dpc-5921	307	6	reduces	reduce	VERB
dpc-5921	307	7	the	the	DET
dpc-5921	307	8	actinic	actinic	ADJ
dpc-5921	307	9	keratosis	keratosis	NOUN
dpc-5921	307	10	area	area	NOUN
dpc-5921	307	11	and	and	CCONJ
dpc-5921	307	12	severity	severity	NOUN
dpc-5921	307	13	index	index	NOUN
dpc-5921	307	14	in	in	ADP
dpc-5921	307	15	patients	patient	NOUN
dpc-5921	307	16	with	with	ADP
dpc-5921	307	17	actinic	actinic	ADJ
dpc-5921	307	18	keratosis	keratosis	NOUN
dpc-5921	307	19	:	:	PUNCT
dpc-5921	307	20	results	result	NOUN
dpc-5921	307	21	from	from	ADP
dpc-5921	307	22	a	a	DET
dpc-5921	307	23	real	real	ADJ
dpc-5921	307	24	-	-	PUNCT
dpc-5921	307	25	world	world	NOUN
dpc-5921	307	26	study	study	NOUN
dpc-5921	307	27	.	.	PUNCT
dpc-5921	308	1	j	j	PROPN
dpc-5921	308	2	clin	clin	PROPN
dpc-5921	308	3	med	med	PROPN
dpc-5921	308	4	.	.	PUNCT
dpc-5921	309	1	2023;12(14):4837	2023;12(14):4837	X
dpc-5921	309	2	.	.	PUNCT
dpc-5921	310	1	doi	doi	NOUN
dpc-5921	310	2	:	:	PUNCT
dpc-5921	310	3	10.3390	10.3390	NUM
dpc-5921	310	4	/	/	SYM
dpc-5921	310	5	jcm12144837	jcm12144837	NOUN
dpc-5921	310	6	.	.	PUNCT
dpc-5921	311	1	pmid	pmid	NOUN
dpc-5921	311	2	:	:	PUNCT
dpc-5921	311	3	37510952	37510952	NUM
dpc-5921	311	4	.	.	PUNCT
dpc-5921	312	1	12	12	NUM
dpc-5921	312	2	.	.	PUNCT
dpc-5921	313	1	eisen	eisen	PROPN
dpc-5921	313	2	db	db	PROPN
dpc-5921	313	3	,	,	PUNCT
dpc-5921	313	4	asgari	asgari	PROPN
dpc-5921	313	5	mm	mm	PROPN
dpc-5921	313	6	,	,	PUNCT
dpc-5921	313	7	bennett	bennett	PROPN
dpc-5921	313	8	dd	dd	PROPN
dpc-5921	313	9	,	,	PUNCT
dpc-5921	313	10	et	et	PROPN
dpc-5921	313	11	al	al	PROPN
dpc-5921	313	12	.	.	PUNCT
dpc-5921	313	13	guidelines	guideline	NOUN
dpc-5921	313	14	of	of	ADP
dpc-5921	313	15	care	care	NOUN
dpc-5921	313	16	for	for	ADP
dpc-5921	313	17	the	the	DET
dpc-5921	313	18	management	management	NOUN
dpc-5921	313	19	of	of	ADP
dpc-5921	313	20	actinic	actinic	ADJ
dpc-5921	313	21	keratosis	keratosis	NOUN
dpc-5921	313	22	.	.	PUNCT
dpc-5921	314	1	j	j	PROPN
dpc-5921	314	2	am	be	AUX
dpc-5921	314	3	acad	acad	ADJ
dpc-5921	314	4	dermatol	dermatol	NOUN
dpc-5921	314	5	.	.	PUNCT
dpc-5921	315	1	2021;85(4):e209	2021;85(4):e209	NOUN
dpc-5921	315	2	-	-	PUNCT
dpc-5921	315	3	e233	e233	PROPN
dpc-5921	315	4	.	.	PUNCT
dpc-5921	315	5	doi	doi	NOUN
dpc-5921	315	6	:	:	PUNCT
dpc-5921	315	7	10.1016	10.1016	NUM
dpc-5921	315	8	/	/	SYM
dpc-5921	315	9	j.jaad.2021.02.082	j.jaad.2021.02.082	PROPN
dpc-5921	315	10	.	.	PUNCT
dpc-5921	316	1	pmid	pmid	PROPN
dpc-5921	316	2	:	:	PUNCT
dpc-5921	316	3	33820677	33820677	NUM
dpc-5921	316	4	.	.	PUNCT
dpc-5921	317	1	13	13	NUM
dpc-5921	317	2	.	.	X
dpc-5921	317	3	sinclair	sinclair	PROPN
dpc-5921	317	4	r	r	PROPN
dpc-5921	317	5	,	,	PUNCT
dpc-5921	317	6	baker	baker	PROPN
dpc-5921	317	7	c	c	PROPN
dpc-5921	317	8	,	,	PUNCT
dpc-5921	317	9	spelman	spelman	PROPN
dpc-5921	317	10	l	l	PROPN
dpc-5921	317	11	,	,	PUNCT
dpc-5921	317	12	supranowicz	supranowicz	PROPN
dpc-5921	317	13	m	m	PROPN
dpc-5921	317	14	,	,	PUNCT
dpc-5921	317	15	macmahon	macmahon	PROPN
dpc-5921	317	16	b.	b.	PROPN
dpc-5921	318	1	a	a	DET
dpc-5921	318	2	review	review	NOUN
dpc-5921	318	3	of	of	ADP
dpc-5921	318	4	actinic	actinic	ADJ
dpc-5921	318	5	keratosis	keratosis	NOUN
dpc-5921	318	6	,	,	PUNCT
dpc-5921	318	7	skin	skin	NOUN
dpc-5921	318	8	field	field	NOUN
dpc-5921	318	9	cancerisation	cancerisation	NOUN
dpc-5921	318	10	and	and	CCONJ
dpc-5921	318	11	the	the	DET
dpc-5921	318	12	efficacy	efficacy	NOUN
dpc-5921	318	13	of	of	ADP
dpc-5921	318	14	topical	topical	ADJ
dpc-5921	318	15	therapies	therapy	NOUN
dpc-5921	318	16	.	.	PUNCT
dpc-5921	319	1	australas	australas	PROPN
dpc-5921	319	2	j	j	PROPN
dpc-5921	319	3	dermatol	dermatol	NOUN
dpc-5921	319	4	.	.	PUNCT
dpc-5921	320	1	2021;62(2	2021;62(2	NUM
dpc-5921	320	2	):	):	PUNCT
dpc-5921	320	3	119	119	NUM
dpc-5921	320	4	-	-	SYM
dpc-5921	320	5	123	123	NUM
dpc-5921	320	6	.	.	PUNCT
dpc-5921	321	1	doi	doi	NOUN
dpc-5921	321	2	:	:	PUNCT
dpc-5921	321	3	10.1111	10.1111	NUM
dpc-5921	321	4	/	/	SYM
dpc-5921	321	5	ajd.13447	ajd.13447	PROPN
dpc-5921	321	6	.	.	PUNCT
dpc-5921	322	1	pmid	pmid	NOUN
dpc-5921	322	2	:	:	PUNCT
dpc-5921	322	3	32840870	32840870	NUM
dpc-5921	322	4	.	.	PUNCT
dpc-5921	323	1	14	14	NUM
dpc-5921	323	2	.	.	PUNCT
dpc-5921	324	1	conforti	conforti	PROPN
dpc-5921	324	2	c	c	PROPN
dpc-5921	324	3	,	,	PUNCT
dpc-5921	324	4	ambrosio	ambrosio	PROPN
dpc-5921	324	5	l	l	PROPN
dpc-5921	324	6	,	,	PUNCT
dpc-5921	324	7	retrosi	retrosi	NOUN
dpc-5921	324	8	c	c	NOUN
dpc-5921	324	9	,	,	PUNCT
dpc-5921	324	10	et	et	PROPN
dpc-5921	324	11	al	al	PROPN
dpc-5921	324	12	.	.	PROPN
dpc-5921	325	1	clinical	clinical	ADJ
dpc-5921	325	2	and	and	CCONJ
dpc-5921	325	3	dermoscopic	dermoscopic	ADJ
dpc-5921	325	4	diagnosis	diagnosis	NOUN
dpc-5921	325	5	of	of	ADP
dpc-5921	325	6	actinic	actinic	ADJ
dpc-5921	325	7	keratosis	keratosis	NOUN
dpc-5921	325	8	.	.	PUNCT
dpc-5921	326	1	dermatol	dermatol	NOUN
dpc-5921	326	2	pract	pract	PROPN
dpc-5921	326	3	concept	concept	NOUN
dpc-5921	326	4	.	.	PUNCT
dpc-5921	327	1	2024;14(3	2024;14(3	NUM
dpc-5921	327	2	s1):e2024147s	s1):e2024147s	PROPN
dpc-5921	327	3	.	.	PUNCT
dpc-5921	328	1	doi	doi	NOUN
dpc-5921	328	2	:	:	PUNCT
dpc-5921	328	3	10.5826	10.5826	NUM
dpc-5921	328	4	/	/	SYM
dpc-5921	328	5	dpc.1403s1a147s	dpc.1403s1a147s	PROPN
dpc-5921	328	6	.	.	PUNCT
dpc-5921	329	1	pmid	pmid	NOUN
dpc-5921	329	2	:	:	PUNCT
dpc-5921	329	3	39133638	39133638	NUM
dpc-5921	329	4	.	.	PUNCT
dpc-5921	330	1	15	15	NUM
dpc-5921	330	2	.	.	PUNCT
dpc-5921	330	3	dréno	dréno	PROPN
dpc-5921	330	4	b	b	PROPN
dpc-5921	330	5	,	,	PUNCT
dpc-5921	330	6	cerio	cerio	PROPN
dpc-5921	330	7	r	r	PROPN
dpc-5921	330	8	,	,	PUNCT
dpc-5921	330	9	dirschka	dirschka	PROPN
dpc-5921	330	10	t	t	PROPN
dpc-5921	330	11	,	,	PUNCT
dpc-5921	330	12	et	et	PROPN
dpc-5921	330	13	al	al	PROPN
dpc-5921	330	14	.	.	PUNCT
dpc-5921	331	1	a	a	DET
dpc-5921	331	2	novel	novel	ADJ
dpc-5921	331	3	actinic	actinic	ADJ
dpc-5921	331	4	keratosis	keratosis	NOUN
dpc-5921	331	5	field	field	NOUN
dpc-5921	331	6	assessment	assessment	NOUN
dpc-5921	331	7	scale	scale	NOUN
dpc-5921	331	8	for	for	ADP
dpc-5921	331	9	gradingactinic	gradingactinic	ADJ
dpc-5921	331	10	keratosis	keratosis	NOUN
dpc-5921	331	11	disease	disease	NOUN
dpc-5921	331	12	severity	severity	NOUN
dpc-5921	331	13	.	.	PUNCT
dpc-5921	332	1	acta	acta	PROPN
dpc-5921	332	2	derm	derm	PROPN
dpc-5921	332	3	venereol	venereol	NOUN
dpc-5921	332	4	.	.	PUNCT
dpc-5921	333	1	2017;97(9):1108	2017;97(9):1108	NUM
dpc-5921	333	2	-	-	SYM
dpc-5921	333	3	1113	1113	NUM
dpc-5921	333	4	.	.	PUNCT
dpc-5921	334	1	doi	doi	NOUN
dpc-5921	334	2	:	:	PUNCT
dpc-5921	334	3	10.2340/00015555	10.2340/00015555	NUM
dpc-5921	334	4	-	-	SYM
dpc-5921	334	5	2710	2710	NUM
dpc-5921	334	6	.	.	PUNCT
dpc-5921	335	1	pmid	pmid	NOUN
dpc-5921	335	2	:	:	PUNCT
dpc-5921	335	3	28536731	28536731	NUM
dpc-5921	335	4	.	.	PUNCT
dpc-5921	336	1	16	16	NUM
dpc-5921	336	2	.	.	PUNCT
dpc-5921	337	1	willenbrink	willenbrink	PROPN
dpc-5921	337	2	tj	tj	PROPN
dpc-5921	337	3	,	,	PUNCT
dpc-5921	337	4	ruiz	ruiz	NOUN
dpc-5921	337	5	es	es	PROPN
dpc-5921	337	6	,	,	PUNCT
dpc-5921	337	7	cornejo	cornejo	PROPN
dpc-5921	337	8	cm	cm	PROPN
dpc-5921	337	9	,	,	PUNCT
dpc-5921	337	10	schmults	schmults	PROPN
dpc-5921	337	11	cd	cd	PROPN
dpc-5921	337	12	,	,	PUNCT
dpc-5921	337	13	arron	arron	PROPN
dpc-5921	337	14	st	st	PROPN
dpc-5921	337	15	,	,	PUNCT
dpc-5921	337	16	jambusaria	jambusaria	PROPN
dpc-5921	337	17	-	-	PUNCT
dpc-5921	337	18	pahlajani	pahlajani	ADJ
dpc-5921	337	19	a.	a.	NOUN
dpc-5921	337	20	field	field	NOUN
dpc-5921	337	21	cancerization	cancerization	NOUN
dpc-5921	337	22	:	:	PUNCT
dpc-5921	338	1	definition	definition	NOUN
dpc-5921	338	2	,	,	PUNCT
dpc-5921	338	3	epidemiology	epidemiology	NOUN
dpc-5921	338	4	,	,	PUNCT
dpc-5921	338	5	risk	risk	NOUN
dpc-5921	338	6	factors	factor	NOUN
dpc-5921	338	7	,	,	PUNCT
dpc-5921	338	8	and	and	CCONJ
dpc-5921	338	9	outcomes	outcome	NOUN
dpc-5921	338	10	.	.	PUNCT
dpc-5921	339	1	j	j	PROPN
dpc-5921	339	2	am	be	AUX
dpc-5921	339	3	acad	acad	ADJ
dpc-5921	339	4	dermatol	dermatol	NOUN
dpc-5921	339	5	.	.	PUNCT
dpc-5921	340	1	2020;83(3):709	2020;83(3):709	NUM
dpc-5921	340	2	-	-	PUNCT
dpc-5921	340	3	717	717	PROPN
dpc-5921	340	4	.	.	PUNCT
dpc-5921	341	1	doi	doi	NOUN
dpc-5921	341	2	:	:	PUNCT
dpc-5921	341	3	10.1016	10.1016	NUM
dpc-5921	341	4	/	/	SYM
dpc-5921	341	5	j.jaad.2020.03.126	j.jaad.2020.03.126	PROPN
dpc-5921	341	6	.	.	PUNCT
dpc-5921	342	1	pmid	pmid	NOUN
dpc-5921	342	2	:	:	PUNCT
dpc-5921	342	3	32387665	32387665	NUM
dpc-5921	342	4	.	.	PUNCT
dpc-5921	343	1	17	17	NUM
dpc-5921	343	2	.	.	PUNCT
dpc-5921	344	1	figueras	figueras	PROPN
dpc-5921	344	2	nart	nart	PROPN
dpc-5921	344	3	i	i	PRON
dpc-5921	344	4	,	,	PUNCT
dpc-5921	344	5	cerio	cerio	PROPN
dpc-5921	344	6	r	r	PROPN
dpc-5921	344	7	,	,	PUNCT
dpc-5921	344	8	dirschka	dirschka	PROPN
dpc-5921	344	9	t	t	PROPN
dpc-5921	344	10	,	,	PUNCT
dpc-5921	344	11	et	et	PROPN
dpc-5921	344	12	al	al	PROPN
dpc-5921	344	13	.	.	PROPN
dpc-5921	344	14	,	,	PUNCT
dpc-5921	344	15	progressing	progress	VERB
dpc-5921	344	16	evidence	evidence	NOUN
dpc-5921	344	17	in	in	ADP
dpc-5921	344	18	ak	ak	PROPN
dpc-5921	344	19	(	(	PUNCT
dpc-5921	344	20	peak	peak	NOUN
dpc-5921	344	21	)	)	PUNCT
dpc-5921	344	22	working	working	NOUN
dpc-5921	344	23	group	group	NOUN
dpc-5921	344	24	.	.	PUNCT
dpc-5921	345	1	defining	define	VERB
dpc-5921	345	2	the	the	DET
dpc-5921	345	3	actinic	actinic	ADJ
dpc-5921	345	4	keratosis	keratosis	NOUN
dpc-5921	345	5	field	field	NOUN
dpc-5921	345	6	:	:	PUNCT
dpc-5921	345	7	a	a	DET
dpc-5921	345	8	literature	literature	NOUN
dpc-5921	345	9	review	review	NOUN
dpc-5921	345	10	and	and	CCONJ
dpc-5921	345	11	discussion	discussion	NOUN
dpc-5921	345	12	.	.	PUNCT
dpc-5921	346	1	j	j	PROPN
dpc-5921	346	2	eur	eur	PROPN
dpc-5921	346	3	acad	acad	PROPN
dpc-5921	346	4	dermatol	dermatol	NOUN
dpc-5921	346	5	venereol	venereol	NOUN
dpc-5921	346	6	.	.	PUNCT
dpc-5921	347	1	2018;32(4):544	2018;32(4):544	NUM
dpc-5921	347	2	-	-	SYM
dpc-5921	347	3	563	563	NUM
dpc-5921	347	4	.	.	PUNCT
dpc-5921	348	1	doi	doi	NOUN
dpc-5921	348	2	:	:	PUNCT
dpc-5921	348	3	10.1111	10.1111	NUM
dpc-5921	348	4	/	/	SYM
dpc-5921	348	5	jdv.14652	jdv.14652	PROPN
dpc-5921	348	6	.	.	PUNCT
dpc-5921	349	1	pmid	pmid	NOUN
dpc-5921	349	2	:	:	PUNCT
dpc-5921	349	3	29055153	29055153	NUM
dpc-5921	349	4	.	.	PUNCT
dpc-5921	350	1	18	18	NUM
dpc-5921	350	2	.	.	X
dpc-5921	350	3	tan	tan	PROPN
dpc-5921	350	4	jm	jm	PROPN
dpc-5921	350	5	,	,	PUNCT
dpc-5921	350	6	lambie	lambie	PROPN
dpc-5921	350	7	d	d	PROPN
dpc-5921	350	8	,	,	PUNCT
dpc-5921	350	9	sinnya	sinnya	PROPN
dpc-5921	350	10	s	s	PROPN
dpc-5921	350	11	,	,	PUNCT
dpc-5921	350	12	et	et	PROPN
dpc-5921	350	13	al	al	PROPN
dpc-5921	350	14	.	.	PROPN
dpc-5921	350	15	histopathology	histopathology	NOUN
dpc-5921	350	16	and	and	CCONJ
dpc-5921	350	17	reflectance	reflectance	NOUN
dpc-5921	350	18	confocal	confocal	ADJ
dpc-5921	350	19	microscopy	microscopy	NOUN
dpc-5921	350	20	features	feature	NOUN
dpc-5921	350	21	of	of	ADP
dpc-5921	350	22	photodamaged	photodamage	VERB
dpc-5921	350	23	skin	skin	NOUN
dpc-5921	350	24	and	and	CCONJ
dpc-5921	350	25	actinic	actinic	ADJ
dpc-5921	350	26	keratosis	keratosis	NOUN
dpc-5921	350	27	.	.	PUNCT
dpc-5921	351	1	j	j	PROPN
dpc-5921	351	2	eur	eur	PROPN
dpc-5921	351	3	acad	acad	PROPN
dpc-5921	351	4	dermatol	dermatol	NOUN
dpc-5921	351	5	venereol	venereol	NOUN
dpc-5921	351	6	.	.	PUNCT
dpc-5921	352	1	2016;30(11	2016;30(11	NUM
dpc-5921	352	2	):	):	PUNCT
dpc-5921	352	3	1901	1901	NUM
dpc-5921	352	4	-	-	SYM
dpc-5921	352	5	1911	1911	NUM
dpc-5921	352	6	.	.	PUNCT
dpc-5921	353	1	doi	doi	NOUN
dpc-5921	353	2	:	:	PUNCT
dpc-5921	353	3	10.1111	10.1111	NUM
dpc-5921	353	4	/	/	SYM
dpc-5921	353	5	jdv.13699	jdv.13699	NOUN
dpc-5921	353	6	.	.	PUNCT
dpc-5921	354	1	pmid	pmid	NOUN
dpc-5921	354	2	:	:	PUNCT
dpc-5921	354	3	27298142	27298142	NUM
dpc-5921	354	4	.	.	PUNCT
dpc-5921	355	1	19	19	NUM
dpc-5921	355	2	.	.	PUNCT
dpc-5921	355	3	szeimies	szeimies	PROPN
dpc-5921	355	4	rm	rm	PROPN
dpc-5921	355	5	,	,	PUNCT
dpc-5921	355	6	ulrich	ulrich	PROPN
dpc-5921	355	7	c	c	PROPN
dpc-5921	355	8	,	,	PUNCT
dpc-5921	355	9	ferrándiz	ferrándiz	NOUN
dpc-5921	355	10	-	-	PUNCT
dpc-5921	355	11	pulido	pulido	NOUN
dpc-5921	355	12	c	c	NOUN
dpc-5921	355	13	,	,	PUNCT
dpc-5921	355	14	et	et	PROPN
dpc-5921	355	15	al	al	PROPN
dpc-5921	355	16	.	.	PUNCT
dpc-5921	356	1	the	the	DET
dpc-5921	356	2	“	"	PUNCT
dpc-5921	356	3	personalising	personalise	VERB
dpc-5921	356	4	actinic	actinic	ADJ
dpc-5921	356	5	keratosis	keratosis	NOUN
dpc-5921	356	6	treatment	treatment	NOUN
dpc-5921	356	7	for	for	ADP
dpc-5921	356	8	immunocompromised	immunocompromise	VERB
dpc-5921	356	9	patients	patient	NOUN
dpc-5921	356	10	”	"	PUNCT
dpc-5921	356	11	(	(	PUNCT
dpc-5921	356	12	im	im	NOUN
dpc-5921	356	13	-	-	PUNCT
dpc-5921	356	14	pakt	pakt	NOUN
dpc-5921	356	15	)	)	PUNCT
dpc-5921	356	16	project	project	NOUN
dpc-5921	356	17	:	:	PUNCT
dpc-5921	356	18	an	an	DET
dpc-5921	356	19	expert	expert	ADJ
dpc-5921	356	20	panel	panel	NOUN
dpc-5921	356	21	opinion	opinion	NOUN
dpc-5921	356	22	.	.	PUNCT
dpc-5921	357	1	dermatol	dermatol	NOUN
dpc-5921	357	2	ther	ther	ADV
dpc-5921	357	3	(	(	PUNCT
dpc-5921	357	4	heidelb	heidelb	NOUN
dpc-5921	357	5	)	)	PUNCT
dpc-5921	357	6	.	.	PUNCT
dpc-5921	358	1	2024;14(7):1739	2024;14(7):1739	NUM
dpc-5921	358	2	-	-	SYM
dpc-5921	358	3	1753	1753	NUM
dpc-5921	358	4	.	.	PUNCT
dpc-5921	359	1	doi	doi	NOUN
dpc-5921	359	2	:	:	PUNCT
dpc-5921	359	3	10.1007	10.1007	NUM
dpc-5921	359	4	/	/	SYM
dpc-5921	359	5	s13555	s13555	PROPN
dpc-5921	359	6	-024	-024	PROPN
dpc-5921	359	7	-	-	PUNCT
dpc-5921	359	8	01215	01215	NUM
dpc-5921	359	9	-	-	PUNCT
dpc-5921	359	10	y.	y.	NOUN
dpc-5921	359	11	pmid	pmid	PROPN
dpc-5921	359	12	:	:	PUNCT
dpc-5921	359	13	38902589	38902589	NUM
dpc-5921	359	14	.	.	PUNCT
dpc-5921	360	1	20	20	NUM
dpc-5921	360	2	.	.	PUNCT
dpc-5921	361	1	olsen	olsen	PROPN
dpc-5921	361	2	ea	ea	PROPN
dpc-5921	361	3	,	,	PUNCT
dpc-5921	361	4	abernethy	abernethy	ADJ
dpc-5921	361	5	ml	ml	NOUN
dpc-5921	361	6	,	,	PUNCT
dpc-5921	361	7	kulp	kulp	NOUN
dpc-5921	361	8	-	-	PUNCT
dpc-5921	361	9	shorten	shorten	NOUN
dpc-5921	361	10	c	c	NOUN
dpc-5921	361	11	,	,	PUNCT
dpc-5921	361	12	et	et	PROPN
dpc-5921	361	13	al	al	PROPN
dpc-5921	361	14	.	.	PUNCT
dpc-5921	362	1	a	a	DET
dpc-5921	362	2	double	double	ADJ
dpc-5921	362	3	-	-	PUNCT
dpc-5921	362	4	blind	blind	ADJ
dpc-5921	362	5	,	,	PUNCT
dpc-5921	362	6	vehicle	vehicle	NOUN
dpc-5921	362	7	-	-	PUNCT
dpc-5921	362	8	controlled	control	VERB
dpc-5921	362	9	study	study	NOUN
dpc-5921	362	10	evaluating	evaluate	VERB
dpc-5921	362	11	masoprocol	masoprocol	ADJ
dpc-5921	362	12	cream	cream	NOUN
dpc-5921	362	13	in	in	ADP
dpc-5921	362	14	the	the	DET
dpc-5921	362	15	treatment	treatment	NOUN
dpc-5921	362	16	of	of	ADP
dpc-5921	362	17	actinic	actinic	ADJ
dpc-5921	362	18	keratoses	keratose	NOUN
dpc-5921	362	19	on	on	ADP
dpc-5921	362	20	the	the	DET
dpc-5921	362	21	head	head	NOUN
dpc-5921	362	22	and	and	CCONJ
dpc-5921	362	23	neck	neck	NOUN
dpc-5921	362	24	.	.	PUNCT
dpc-5921	363	1	j	j	PROPN
dpc-5921	363	2	am	be	AUX
dpc-5921	363	3	acad	acad	ADJ
dpc-5921	363	4	dermatol	dermatol	NOUN
dpc-5921	363	5	.	.	PUNCT
dpc-5921	364	1	1991;24(5	1991;24(5	NUM
dpc-5921	364	2	pt	pt	PROPN
dpc-5921	364	3	1):738	1):738	PROPN
dpc-5921	364	4	-	-	SYM
dpc-5921	364	5	43	43	NUM
dpc-5921	364	6	.	.	PUNCT
dpc-5921	365	1	doi	doi	NOUN
dpc-5921	365	2	:	:	PUNCT
dpc-5921	365	3	10.1016/01909622(91)70113	10.1016/01909622(91)70113	NUM
dpc-5921	365	4	-	-	PUNCT
dpc-5921	365	5	g.	g.	NOUN
dpc-5921	365	6	pmid	pmid	PROPN
dpc-5921	365	7	:	:	PUNCT
dpc-5921	365	8	1869646	1869646	NUM
dpc-5921	365	9	.	.	PUNCT
dpc-5921	366	1	21	21	NUM
dpc-5921	366	2	.	.	X
dpc-5921	367	1	zalaudek	zalaudek	PROPN
dpc-5921	367	2	i	i	PRON
dpc-5921	367	3	,	,	PUNCT
dpc-5921	367	4	giacomel	giacomel	PROPN
dpc-5921	367	5	j	j	PROPN
dpc-5921	367	6	,	,	PUNCT
dpc-5921	367	7	schmid	schmid	PROPN
dpc-5921	367	8	k	k	PROPN
dpc-5921	367	9	,	,	PUNCT
dpc-5921	367	10	et	et	PROPN
dpc-5921	367	11	al	al	PROPN
dpc-5921	367	12	.	.	PROPN
dpc-5921	367	13	dermatoscopy	dermatoscopy	NOUN
dpc-5921	367	14	of	of	ADP
dpc-5921	367	15	facial	facial	ADJ
dpc-5921	367	16	actinic	actinic	ADJ
dpc-5921	367	17	keratosis	keratosis	NOUN
dpc-5921	367	18	,	,	PUNCT
dpc-5921	367	19	intraepidermal	intraepidermal	ADJ
dpc-5921	367	20	carcinoma	carcinoma	NOUN
dpc-5921	367	21	,	,	PUNCT
dpc-5921	367	22	and	and	CCONJ
dpc-5921	367	23	invasive	invasive	ADJ
dpc-5921	367	24	squamous	squamous	ADJ
dpc-5921	367	25	cell	cell	NOUN
dpc-5921	367	26	carcinoma	carcinoma	NOUN
dpc-5921	367	27	:	:	PUNCT
dpc-5921	367	28	a	a	DET
dpc-5921	367	29	progression	progression	NOUN
dpc-5921	367	30	model	model	NOUN
dpc-5921	367	31	.	.	PUNCT
dpc-5921	368	1	j	j	PROPN
dpc-5921	368	2	am	be	AUX
dpc-5921	368	3	acad	acad	ADJ
dpc-5921	368	4	dermatol	dermatol	NOUN
dpc-5921	368	5	.	.	PUNCT
dpc-5921	369	1	2012;66(4):589	2012;66(4):589	NUM
dpc-5921	369	2	-	-	PUNCT
dpc-5921	369	3	97	97	NUM
dpc-5921	369	4	.	.	PUNCT
dpc-5921	370	1	doi	doi	NOUN
dpc-5921	370	2	:	:	PUNCT
dpc-5921	370	3	10.1016	10.1016	NUM
dpc-5921	370	4	/	/	SYM
dpc-5921	370	5	j.jaad.2011.02.011	j.jaad.2011.02.011	PROPN
dpc-5921	370	6	.	.	PUNCT
dpc-5921	371	1	pmid	pmid	NOUN
dpc-5921	371	2	:	:	PUNCT
dpc-5921	371	3	21839538	21839538	NUM
dpc-5921	371	4	.	.	PUNCT
dpc-5921	372	1	22	22	NUM
dpc-5921	372	2	.	.	PUNCT
dpc-5921	373	1	cinotti	cinotti	PROPN
dpc-5921	373	2	e	e	NOUN
dpc-5921	373	3	,	,	PUNCT
dpc-5921	373	4	tognetti	tognetti	PROPN
dpc-5921	373	5	l	l	PROPN
dpc-5921	373	6	,	,	PUNCT
dpc-5921	373	7	cartocci	cartocci	VERB
dpc-5921	373	8	a	a	PRON
dpc-5921	373	9	,	,	PUNCT
dpc-5921	373	10	et	et	PROPN
dpc-5921	373	11	al	al	PROPN
dpc-5921	373	12	.	.	PROPN
dpc-5921	373	13	line	line	NOUN
dpc-5921	373	14	-	-	PUNCT
dpc-5921	373	15	field	field	NOUN
dpc-5921	373	16	confocal	confocal	ADJ
dpc-5921	373	17	optical	optical	ADJ
dpc-5921	373	18	coherence	coherence	NOUN
dpc-5921	373	19	tomography	tomography	NOUN
dpc-5921	373	20	for	for	ADP
dpc-5921	373	21	actinic	actinic	ADJ
dpc-5921	373	22	keratosis	keratosis	NOUN
dpc-5921	373	23	and	and	CCONJ
dpc-5921	373	24	squamous	squamous	ADJ
dpc-5921	373	25	cell	cell	NOUN
dpc-5921	373	26	carcinoma	carcinoma	NOUN
dpc-5921	373	27	:	:	PUNCT
dpc-5921	373	28	a	a	DET
dpc-5921	373	29	descriptive	descriptive	ADJ
dpc-5921	373	30	study	study	NOUN
dpc-5921	373	31	.	.	PUNCT
dpc-5921	374	1	clin	clin	PROPN
dpc-5921	374	2	exp	exp	NOUN
dpc-5921	374	3	dermatol	dermatol	NOUN
dpc-5921	374	4	.	.	PUNCT
dpc-5921	375	1	2021;46(8):1530	2021;46(8):1530	PROPN
dpc-5921	375	2	-	-	PUNCT
dpc-5921	375	3	1541	1541	NUM
dpc-5921	375	4	.	.	PUNCT
dpc-5921	376	1	doi:10.1111	doi:10.1111	NOUN
dpc-5921	376	2	/	/	SYM
dpc-5921	376	3	ced.14801pmid	ced.14801pmid	NOUN
dpc-5921	376	4	:	:	PUNCT
dpc-5921	376	5	34115900	34115900	NUM
dpc-5921	376	6	.	.	PUNCT
dpc-5921	377	1	23	23	NUM
dpc-5921	377	2	.	.	PUNCT
dpc-5921	378	1	ruini	ruini	PROPN
dpc-5921	378	2	c	c	PROPN
dpc-5921	378	3	,	,	PUNCT
dpc-5921	378	4	schuh	schuh	PROPN
dpc-5921	378	5	s	s	PROPN
dpc-5921	378	6	,	,	PUNCT
dpc-5921	378	7	gust	gust	PROPN
dpc-5921	378	8	c	c	NOUN
dpc-5921	378	9	,	,	PUNCT
dpc-5921	378	10	et	et	PROPN
dpc-5921	378	11	al	al	PROPN
dpc-5921	378	12	.	.	PROPN
dpc-5921	379	1	in	in	ADP
dpc-5921	379	2	-	-	PUNCT
dpc-5921	379	3	vivo	vivo	ADJ
dpc-5921	379	4	lc	lc	PROPN
dpc-5921	379	5	-	-	PUNCT
dpc-5921	379	6	oct	oct	NOUN
dpc-5921	379	7	evaluation	evaluation	NOUN
dpc-5921	379	8	of	of	ADP
dpc-5921	379	9	the	the	DET
dpc-5921	379	10	downward	downward	ADJ
dpc-5921	379	11	proliferation	proliferation	NOUN
dpc-5921	379	12	pattern	pattern	NOUN
dpc-5921	379	13	of	of	ADP
dpc-5921	379	14	keratinocytes	keratinocyte	NOUN
dpc-5921	379	15	in	in	ADP
dpc-5921	379	16	actinic	actinic	ADJ
dpc-5921	379	17	keratosis	keratosis	NOUN
dpc-5921	379	18	in	in	ADP
dpc-5921	379	19	comparison	comparison	NOUN
dpc-5921	379	20	with	with	ADP
dpc-5921	379	21	histology	histology	NOUN
dpc-5921	379	22	:	:	PUNCT
dpc-5921	379	23	first	first	ADJ
dpc-5921	379	24	impressions	impression	NOUN
dpc-5921	379	25	from	from	ADP
dpc-5921	379	26	a	a	DET
dpc-5921	379	27	pilot	pilot	NOUN
dpc-5921	379	28	study	study	NOUN
dpc-5921	379	29	.	.	PUNCT
dpc-5921	380	1	cancers	cancer	NOUN
dpc-5921	380	2	(	(	PUNCT
dpc-5921	380	3	basel	basel	PROPN
dpc-5921	380	4	)	)	PUNCT
dpc-5921	380	5	.	.	PUNCT
dpc-5921	381	1	2021;13(12):2856	2021;13(12):2856	X
dpc-5921	381	2	.	.	PUNCT
dpc-5921	382	1	doi	doi	NOUN
dpc-5921	382	2	:	:	PUNCT
dpc-5921	382	3	10.3390	10.3390	NUM
dpc-5921	382	4	/cancers13122856	/cancers13122856	PUNCT
dpc-5921	382	5	.	.	PUNCT
dpc-5921	383	1	pmid	pmid	NOUN
dpc-5921	383	2	:	:	PUNCT
dpc-5921	383	3	34201052	34201052	NUM
dpc-5921	383	4	.	.	PUNCT
dpc-5921	384	1	review	review	VERB
dpc-5921	384	2	|	|	ADV
dpc-5921	384	3	dermatol	dermatol	ADJ
dpc-5921	384	4	pract	pract	NOUN
dpc-5921	384	5	concept	concept	NOUN
dpc-5921	384	6	.	.	PUNCT
dpc-5921	385	1	2025;15(3):5921	2025;15(3):5921	NUM
dpc-5921	385	2	11	11	NUM
dpc-5921	385	3	ther	ther	ADV
dpc-5921	385	4	(	(	PUNCT
dpc-5921	385	5	heidelb	heidelb	NOUN
dpc-5921	385	6	)	)	PUNCT
dpc-5921	385	7	.	.	PUNCT
dpc-5921	386	1	2025;15(1):95	2025;15(1):95	X
dpc-5921	386	2	-	-	SYM
dpc-5921	386	3	110	110	NUM
dpc-5921	386	4	.	.	PUNCT
dpc-5921	387	1	doi	doi	NOUN
dpc-5921	387	2	:	:	PUNCT
dpc-5921	387	3	10.1007	10.1007	NUM
dpc-5921	387	4	/	/	SYM
dpc-5921	387	5	s13555	s13555	PROPN
dpc-5921	387	6	-	-	PUNCT
dpc-5921	387	7	02401310	02401310	NUM
dpc-5921	387	8	-	-	SYM
dpc-5921	387	9	0	0	NUM
dpc-5921	387	10	.	.	PUNCT
dpc-5921	388	1	pmid	pmid	NOUN
dpc-5921	388	2	:	:	PUNCT
dpc-5921	388	3	39614963	39614963	NUM
dpc-5921	388	4	.	.	PUNCT
dpc-5921	389	1	40	40	NUM
dpc-5921	389	2	.	.	PUNCT
dpc-5921	390	1	dubois	dubois	PROPN
dpc-5921	390	2	j	j	PROPN
dpc-5921	390	3	,	,	PUNCT
dpc-5921	390	4	jones	jones	PROPN
dpc-5921	390	5	tm	tm	PROPN
dpc-5921	390	6	,	,	PUNCT
dpc-5921	390	7	lee	lee	PROPN
dpc-5921	390	8	ms	ms	PROPN
dpc-5921	390	9	,	,	PUNCT
dpc-5921	390	10	et	et	PROPN
dpc-5921	390	11	al	al	PROPN
dpc-5921	390	12	.	.	PUNCT
dpc-5921	390	13	pharmacokinetics	pharmacokinetic	NOUN
dpc-5921	390	14	,	,	PUNCT
dpc-5921	390	15	safety	safety	NOUN
dpc-5921	390	16	,	,	PUNCT
dpc-5921	390	17	and	and	CCONJ
dpc-5921	390	18	tolerability	tolerability	NOUN
dpc-5921	390	19	of	of	ADP
dpc-5921	390	20	a	a	DET
dpc-5921	390	21	single	single	ADJ
dpc-5921	390	22	5	5	NUM
dpc-5921	390	23	-	-	PUNCT
dpc-5921	390	24	day	day	NOUN
dpc-5921	390	25	treatment	treatment	NOUN
dpc-5921	390	26	of	of	ADP
dpc-5921	390	27	tirbanibulin	tirbanibulin	PROPN
dpc-5921	390	28	ointment	ointment	NOUN
dpc-5921	390	29	1	1	NUM
dpc-5921	390	30	%	%	NOUN
dpc-5921	390	31	in	in	ADP
dpc-5921	390	32	100	100	NUM
dpc-5921	390	33	 	 	SPACE
dpc-5921	390	34	cm2	cm2	NOUN
dpc-5921	390	35	:	:	PUNCT
dpc-5921	390	36	a	a	DET
dpc-5921	390	37	phase	phase	NOUN
dpc-5921	390	38	1	1	NUM
dpc-5921	390	39	maximal	maximal	ADJ
dpc-5921	390	40	-	-	PUNCT
dpc-5921	390	41	use	use	NOUN
dpc-5921	390	42	trial	trial	NOUN
dpc-5921	390	43	in	in	ADP
dpc-5921	390	44	patients	patient	NOUN
dpc-5921	390	45	with	with	ADP
dpc-5921	390	46	actinic	actinic	ADJ
dpc-5921	390	47	keratosis	keratosis	NOUN
dpc-5921	390	48	.	.	PUNCT
dpc-5921	391	1	clin	clin	PROPN
dpc-5921	391	2	pharmacol	pharmacol	PROPN
dpc-5921	391	3	drug	drug	PROPN
dpc-5921	391	4	dev	dev	PROPN
dpc-5921	391	5	.	.	PUNCT
dpc-5921	392	1	2024;13(2	2024;13(2	NUM
dpc-5921	392	2	):	):	PUNCT
dpc-5921	392	3	208	208	NUM
dpc-5921	392	4	-	-	SYM
dpc-5921	392	5	218	218	NUM
dpc-5921	392	6	.	.	PUNCT
dpc-5921	393	1	doi	doi	NOUN
dpc-5921	393	2	:	:	PUNCT
dpc-5921	393	3	10.1002	10.1002	NUM
dpc-5921	393	4	/	/	SYM
dpc-5921	393	5	cpdd.1368	cpdd.1368	PROPN
dpc-5921	393	6	.	.	PROPN
dpc-5921	393	7	pmid	pmid	PROPN
dpc-5921	393	8	:	:	PUNCT
dpc-5921	393	9	38185925	38185925	NUM
dpc-5921	393	10	.	.	PUNCT
dpc-5921	394	1	41	41	NUM
dpc-5921	394	2	.	.	PUNCT
dpc-5921	395	1	bhatia	bhatia	PROPN
dpc-5921	395	2	n	n	CCONJ
dpc-5921	395	3	,	,	PUNCT
dpc-5921	395	4	lain	lain	PROPN
dpc-5921	395	5	e	e	NOUN
dpc-5921	395	6	,	,	PUNCT
dpc-5921	395	7	jarell	jarell	ADV
dpc-5921	395	8	a	a	X
dpc-5921	395	9	,	,	PUNCT
dpc-5921	395	10	et	et	PROPN
dpc-5921	395	11	al	al	PROPN
dpc-5921	395	12	.	.	PROPN
dpc-5921	395	13	safety	safety	NOUN
dpc-5921	395	14	and	and	CCONJ
dpc-5921	395	15	tolerability	tolerability	NOUN
dpc-5921	395	16	of	of	ADP
dpc-5921	395	17	tirbanibulin	tirbanibulin	PROPN
dpc-5921	395	18	ointment	ointment	NOUN
dpc-5921	395	19	1	1	NUM
dpc-5921	395	20	%	%	NOUN
dpc-5921	395	21	treatment	treatment	NOUN
dpc-5921	395	22	on	on	ADP
dpc-5921	395	23	100	100	NUM
dpc-5921	395	24	  	  	SPACE
dpc-5921	395	25	cm2	cm2	PROPN
dpc-5921	395	26	of	of	ADP
dpc-5921	395	27	the	the	DET
dpc-5921	395	28	face	face	NOUN
dpc-5921	395	29	or	or	CCONJ
dpc-5921	395	30	scalp	scalp	NOUN
dpc-5921	395	31	in	in	ADP
dpc-5921	395	32	patients	patient	NOUN
dpc-5921	395	33	with	with	ADP
dpc-5921	395	34	actinic	actinic	ADJ
dpc-5921	395	35	keratosis	keratosis	NOUN
dpc-5921	395	36	:	:	PUNCT
dpc-5921	395	37	a	a	DET
dpc-5921	395	38	phase	phase	NOUN
dpc-5921	395	39	3	3	NUM
dpc-5921	395	40	study	study	NOUN
dpc-5921	395	41	.	.	PUNCT
dpc-5921	396	1	jaad	jaad	NOUN
dpc-5921	396	2	int	int	PROPN
dpc-5921	396	3	.	.	PUNCT
dpc-5921	397	1	2024;17:6	2024;17:6	NUM
dpc-5921	397	2	-	-	SYM
dpc-5921	397	3	14	14	NUM
dpc-5921	397	4	.	.	PUNCT
dpc-5921	398	1	doi	doi	NOUN
dpc-5921	398	2	:	:	PUNCT
dpc-5921	398	3	10.1016	10.1016	NUM
dpc-5921	398	4	/	/	SYM
dpc-5921	398	5	j.jdin.2024.07.001	j.jdin.2024.07.001	PROPN
dpc-5921	398	6	.	.	PUNCT
dpc-5921	399	1	pmid	pmid	NOUN
dpc-5921	399	2	:	:	PUNCT
dpc-5921	399	3	39268198	39268198	NUM
dpc-5921	399	4	.	.	PUNCT
dpc-5921	400	1	36	36	NUM
dpc-5921	400	2	.	.	PUNCT
dpc-5921	401	1	pariser	pariser	PROPN
dpc-5921	401	2	dm	dm	PROPN
dpc-5921	401	3	.	.	PUNCT
dpc-5921	401	4	approaches	approach	NOUN
dpc-5921	401	5	to	to	ADP
dpc-5921	401	6	field	field	NOUN
dpc-5921	401	7	therapy	therapy	NOUN
dpc-5921	401	8	for	for	ADP
dpc-5921	401	9	actinic	actinic	ADJ
dpc-5921	401	10	keratoses	keratose	NOUN
dpc-5921	401	11	:	:	PUNCT
dpc-5921	401	12	relating	relate	VERB
dpc-5921	401	13	clinical	clinical	ADJ
dpc-5921	401	14	trial	trial	NOUN
dpc-5921	401	15	results	result	NOUN
dpc-5921	401	16	to	to	ADP
dpc-5921	401	17	real	real	ADJ
dpc-5921	401	18	-	-	PUNCT
dpc-5921	401	19	world	world	NOUN
dpc-5921	401	20	practice	practice	NOUN
dpc-5921	401	21	-	-	PUNCT
dpc-5921	401	22	a	a	DET
dpc-5921	401	23	commentary	commentary	NOUN
dpc-5921	401	24	.	.	PUNCT
dpc-5921	402	1	j	j	PROPN
dpc-5921	402	2	clin	clin	PROPN
dpc-5921	402	3	aesthet	aesthet	PROPN
dpc-5921	402	4	dermatol	dermatol	PROPN
dpc-5921	402	5	.	.	PUNCT
dpc-5921	403	1	2022;15(4):40	2022;15(4):40	NUM
dpc-5921	403	2	-	-	SYM
dpc-5921	403	3	43	43	NUM
dpc-5921	403	4	.	.	PUNCT
dpc-5921	404	1	pmid	pmid	NOUN
dpc-5921	404	2	:	:	PUNCT
dpc-5921	404	3	35465033	35465033	NUM
dpc-5921	404	4	37	37	NUM
dpc-5921	404	5	.	.	PUNCT
dpc-5921	405	1	foley	foley	PROPN
dpc-5921	405	2	p	p	X
dpc-5921	405	3	,	,	PUNCT
dpc-5921	405	4	stockfleth	stockfleth	PROPN
dpc-5921	405	5	e	e	PROPN
dpc-5921	405	6	,	,	PUNCT
dpc-5921	405	7	peris	peris	PROPN
dpc-5921	405	8	k	k	PROPN
dpc-5921	405	9	,	,	PUNCT
dpc-5921	405	10	et	et	PROPN
dpc-5921	405	11	al	al	PROPN
dpc-5921	405	12	.	.	PROPN
dpc-5921	405	13	adherence	adherence	NOUN
dpc-5921	405	14	to	to	ADP
dpc-5921	405	15	topical	topical	ADJ
dpc-5921	405	16	therapies	therapy	NOUN
dpc-5921	405	17	in	in	ADP
dpc-5921	405	18	actinic	actinic	ADJ
dpc-5921	405	19	keratosis	keratosis	NOUN
dpc-5921	405	20	:	:	PUNCT
dpc-5921	405	21	a	a	DET
dpc-5921	405	22	literature	literature	NOUN
dpc-5921	405	23	review	review	NOUN
dpc-5921	405	24	.	.	PUNCT
dpc-5921	406	1	j	j	PROPN
dpc-5921	406	2	dermatolog	dermatolog	PROPN
dpc-5921	406	3	treat	treat	NOUN
dpc-5921	406	4	.	.	PUNCT
dpc-5921	407	1	2016;27(6):538	2016;27(6):538	NUM
dpc-5921	407	2	-	-	SYM
dpc-5921	407	3	545	545	NUM
dpc-5921	407	4	.	.	PUNCT
dpc-5921	408	1	doi	doi	NOUN
dpc-5921	408	2	:	:	PUNCT
dpc-5921	408	3	10.1080/09546634.2016.1178372	10.1080/09546634.2016.1178372	NUM
dpc-5921	408	4	.	.	PUNCT
dpc-5921	409	1	pmid	pmid	NOUN
dpc-5921	409	2	:	:	PUNCT
dpc-5921	409	3	27161045	27161045	NUM
dpc-5921	409	4	.	.	PUNCT
dpc-5921	410	1	38	38	NUM
dpc-5921	410	2	.	.	PUNCT
dpc-5921	411	1	li	li	PROPN
dpc-5921	411	2	pomi	pomi	PROPN
dpc-5921	411	3	f	f	PROPN
dpc-5921	411	4	,	,	PUNCT
dpc-5921	411	5	peterle	peterle	PROPN
dpc-5921	411	6	l	l	NOUN
dpc-5921	411	7	,	,	PUNCT
dpc-5921	411	8	d’aloja	d’aloja	PROPN
dpc-5921	411	9	a	a	X
dpc-5921	411	10	,	,	PUNCT
dpc-5921	411	11	di	di	X
dpc-5921	411	12	tano	tano	PROPN
dpc-5921	411	13	a	a	PROPN
dpc-5921	411	14	,	,	PUNCT
dpc-5921	411	15	vaccaro	vaccaro	PROPN
dpc-5921	411	16	m	m	PROPN
dpc-5921	411	17	,	,	PUNCT
dpc-5921	411	18	borgia	borgia	PROPN
dpc-5921	411	19	f.	f.	PROPN
dpc-5921	411	20	anti	anti	ADJ
dpc-5921	411	21	-	-	ADJ
dpc-5921	411	22	aging	aging	ADJ
dpc-5921	411	23	effects	effect	NOUN
dpc-5921	411	24	of	of	ADP
dpc-5921	411	25	tirbanibulin	tirbanibulin	PRON
dpc-5921	411	26	1	1	NUM
dpc-5921	411	27	%	%	NOUN
dpc-5921	411	28	ointment	ointment	NOUN
dpc-5921	411	29	:	:	PUNCT
dpc-5921	411	30	a	a	DET
dpc-5921	411	31	real	real	ADJ
dpc-5921	411	32	-	-	PUNCT
dpc-5921	411	33	life	life	NOUN
dpc-5921	411	34	experience	experience	NOUN
dpc-5921	411	35	.	.	PUNCT
dpc-5921	412	1	dermatol	dermatol	NOUN
dpc-5921	412	2	ther	ther	ADV
dpc-5921	412	3	(	(	PUNCT
dpc-5921	412	4	heidelb	heidelb	NOUN
dpc-5921	412	5	)	)	PUNCT
dpc-5921	412	6	.	.	PUNCT
dpc-5921	413	1	2024;14(6):1683	2024;14(6):1683	PROPN
dpc-5921	413	2	-	-	PUNCT
dpc-5921	413	3	1696	1696	NUM
dpc-5921	413	4	.	.	PUNCT
dpc-5921	414	1	doi	doi	NOUN
dpc-5921	414	2	:	:	PUNCT
dpc-5921	414	3	10.1007	10.1007	NUM
dpc-5921	414	4	/	/	SYM
dpc-5921	414	5	s13555	s13555	PROPN
dpc-5921	414	6	-	-	PUNCT
dpc-5921	414	7	024	024	NUM
dpc-5921	414	8	-	-	PUNCT
dpc-5921	414	9	01178	01178	NUM
dpc-5921	414	10	-	-	PUNCT
dpc-5921	414	11	0	0	NUM
dpc-5921	414	12	.	.	PUNCT
dpc-5921	415	1	pmid	pmid	NOUN
dpc-5921	415	2	:	:	PUNCT
dpc-5921	415	3	38740726	38740726	NUM
dpc-5921	415	4	.	.	PUNCT
dpc-5921	416	1	39	39	NUM
dpc-5921	416	2	.	.	PUNCT
dpc-5921	417	1	li	li	PROPN
dpc-5921	417	2	pomi	pomi	PROPN
dpc-5921	417	3	f	f	PROPN
dpc-5921	417	4	,	,	PUNCT
dpc-5921	417	5	d’aloja	d’aloja	VERB
dpc-5921	417	6	a	a	PRON
dpc-5921	417	7	,	,	PUNCT
dpc-5921	417	8	rottura	rottura	NOUN
dpc-5921	417	9	m	m	PROPN
dpc-5921	417	10	,	,	PUNCT
dpc-5921	417	11	vaccaro	vaccaro	PROPN
dpc-5921	417	12	m	m	PROPN
dpc-5921	417	13	,	,	PUNCT
dpc-5921	417	14	borgia	borgia	PROPN
dpc-5921	417	15	f.	f.	PROPN
dpc-5921	417	16	the	the	DET
dpc-5921	417	17	skin	skin	NOUN
dpc-5921	417	18	-	-	PUNCT
dpc-5921	417	19	lightening	lighten	VERB
dpc-5921	417	20	power	power	NOUN
dpc-5921	417	21	of	of	ADP
dpc-5921	417	22	tirbanibulin	tirbanibulin	DET
dpc-5921	417	23	1	1	NUM
dpc-5921	417	24	%	%	NOUN
dpc-5921	417	25	ointment	ointment	NOUN
dpc-5921	417	26	.	.	PUNCT
dpc-5921	418	1	dermatol	dermatol	NOUN