# bib

id: dr-1417
author: Quatresooz, Pascale; Piérard-Franchimont, Claudine; Paquet, Philippe; Piérard, Gerald E.
title: Cutaneous papules in a patient with AIDS
date: 2010-01-18
pages: 2
extension: .pdf
mime: application/pdf
words: 1234
sentence: 81
flesch: 48
cache: cache/dr-1417.pdf
txt: txt/dr-1417.txt
summary:
  The present case illustrates the dermal clustering and the vascular spread of T. pallidum in a woman with acquired immu no deficiency syndrome. Discussion In the present case, skin immunohisto- chemistry shed some light on the diagnosis of syphilis in an AIDS patient and showed the dermal homing and the microvascular tropism of T. pallidum.


id: dr-2702
title: Epidemiologic and clinicopathologic aspects of Leprosy in Dakar; evaluation of 73 new cases
date: 2011-10-25
pages: 3
extension: .pdf
mime: application/pdf
words: 2189
sentence: 124
flesch: 60
cache: cache/dr-2702.pdf
txt: txt/dr-2702.txt
author:
  Niang, Suzanne Oumou; Diallo, Moussa; Ndiaye, Maodo; Diop, Assane; Diatta, Boubacar Ahy; Wadih, Mohamed; Kane, Assane; Dieng, Mame Thierno; Badiane, Charles Insa

summary:
  Senegal Abstract Hundreds of new leprosy cases are still diag- nosed in Dakar despite all the efforts in the struggle by the national program for elimina- tion of leprosy by the Institute of Applied Lep- rosy in Dakar. Age distribution of new leprosy cases.


id: dr-2476
author: Mehren, Christine R.; Gniadecki, Robert
title: Epidermolysis bullosa acquisita: current diagnosis and therapy
date: 2011-11-28
pages: 4
extension: .pdf
mime: application/pdf
words: 3525
sentence: 203
flesch: 49
cache: cache/dr-2476.pdf
txt: txt/dr-2476.txt
summary:
  Immunoelectron microscopy (IEM) docu- ments the localization of the immune deposits within the dermal-epidermal junction of the skin of EBA patients. The treatment of EBA patients with IVIG has shown encouraging results.


id: dr-1494
author: Mikkelsen, Carsten Sauer; Gelvan, Allan; Ibrahim, Ahmad; Ladefoged, Karin
date: 2010-01-14
pages: 2
extension: .pdf
mime: application/pdf
words: 2690
sentence: 198
flesch: 62
cache: cache/dr-1494.pdf
txt: txt/dr-1494.txt
title:
  A case of rheumatic fever with acute post-streptococcal glomerulonephritis and nephrotic syndrome caused by a cutaneous infection with beta-hemolytic streptococci

summary:
  Culture from the lesion of the right lower extremity was positive for group A No n- co mm er cia l lower extremity was positive for group A β No n- co mm er cia l β- The dynamic nature of group A streptococ- No n- co mm er cia l The dynamic nature of group


id: dr-2073
author: Holst, Anders Vedel; Danielsen, Patricia Louise; Romner, Bertil
title: A severe case of tetracycline-induced intracranial hypertension
date: 2011-01-31
pages: 1
extension: .pdf
mime: application/pdf
words: 839
sentence: 58
flesch: 52
cache: cache/dr-2073.pdf
txt: txt/dr-2073.txt
summary:
  A rare side effect of tetracycline treatment is intracranial hypertension also called pseudotu- mor cerebri (PTC). E-mail: patriciadanielsen@yahoo.dk Key words: tetracycline, intracranial hypertension.


id: dr-1062
author: Park, Gyeong-hun; Han, Seung-seog; Chang, Sung-eun; Choi, Jee-ho
title: Increase of integrin α6+p63+ cells after ultraviolet B irradiation in normal human keratinocytes
date: 2009-12-02
pages: 4
extension: .pdf
mime: application/pdf
words: 271
sentence: 32
flesch: 65
cache: cache/dr-1062.pdf
txt: txt/dr-1062.txt
summary:
  Human keratinocyte stem cells survive for months in sodium chloride and can be suc- cessfully transplanted. Epidermal stem cells.


id: dr-2399
title: Bullous mycosis fungoides associated with an extensive ulcer and a severe leukemoid reaction
date: 2011-12-02
pages: 3
extension: .pdf
mime: application/pdf
words: 3936
sentence: 206
flesch: 60
cache: cache/dr-2399.pdf
txt: txt/dr-2399.txt
author:
  Sato, Shuei; Okamoto, Osamu; Kawamoto, Michifumi; Oishi, Masaki; Yada, Naomi; Kohno, Kazuhiro; Yokoyama, Shigeo; Fujiwara, Sakuhei

summary:
  Lower inlet: Close-up view of the infiltrate (originalmagnification X400); d) bulla on the trunk; e) histological appearance of the bulla (orig- No n- co mm er cia l magnification X400); d) bulla on the trunk; e) histological appearance of the bulla (orig- No n- co mm er cia l ed patients dying within 1 year after the No n- co mm er cia l ed patients dying within 1 year after the Therefore, the forma- No n- co mm er cia l Therefore, the forma- tion of bulla during the course of MF indicates No n- co mm er cia l tion of bulla during the course of MF indicates a poor prognosis, and the extensive ulceration No n- co mm er cia l a poor prognosis, and the extensive ulceration seen in the current case may reflect a step No n- co mm er cia l seen in the current case may reflect a step Many causes of leukemoid reaction areNo n- co mm er cia l Many causes of leukemoid reaction are known, including infections, malignantNo n- co mm er cia l known, including infections, malignant inal magnification X40). Various causes of leukemoid reactions, such as infections, malignant tumors, etc., are known,1,2 and pseudomembranous colitis is a frequent cause of such infections.1,3


id: dr-1998
author: Nakahara, Takeshi; Moroi, Yoichi; Tashiro, Akari; Kiryu, Hiromaro; Furue, Masutaka
title: The interaction of inflammatory cells in granuloma faciale
date: 2010-11-15
pages: 2
extension: .pdf
mime: application/pdf
words: 1587
sentence: 85
flesch: 42
cache: cache/dr-1998.pdf
txt: txt/dr-1998.txt
summary:
  Immunohistochemical staining demonstrated mixed cellular infiltrates intermixed with CD1a+ dendritic cells, CD68+ histiocytes, and CD4+ and CD8+ T cells. Mixed cellular infiltrates intermixed with CD1a+ dendritic cells (DCs), CD68+ histiocytes, and CD4+ and CD8+ T cells were detected immunohistochemically.


id: dr-3329
author: Kumar, Shiva; Okade, Rajendra; Abdul Rahman, Yasmin
title: Unilateral Blaschkoid lichen planus in successive pregnancies
date: 2011-09-29
pages: 2
extension: .pdf
mime: application/pdf
words: 1489
sentence: 108
flesch: 61
cache: cache/dr-3329.pdf
txt: txt/dr-3329.txt
summary:
  A common disorder like lichen planus can very rarely present with pruritic lesions in atypical patterns such as unilateral distribution, painful eruptions and along Blaschko’s lines. Various triggering fac- tors varying from viral infections and vaccina- tions to trauma have been implicated in lichen planus.


id: dr-1270
author: Zhang, Xi-Bao; Zhang, San-Quan; Li, Chang-Xing; Huang, Zhen-Ming; Luo, Yu-Wu
title: Acitretin systemic and retinoic acid 0.1% cream suppression of basal cell carcinoma
date: 2010-03-16
pages: 3
extension: .pdf
mime: application/pdf
words: 2517
sentence: 147
flesch: 63
cache: cache/dr-1270.pdf
txt: txt/dr-1270.txt
summary:
  Skin biopsy revealed infiltration of lym- phocytes around the vessels in dermis and no focal of tumor cells was seen (Figure 3D). (D) Skin biop- sy revealed infiltration of lymphocytes around the vessels indermis, and no focal of tumor cell being seen (×40).


id: dr-3013
author: Kumar, Piyush; Gosai, Anubhav; Mondal, Ashim Kumar; Lal, Niharika Ranjan; Gharami, Ramesh Chandra
title: Granulosis rubra nasi: a rare condition treated successfully with topical tacrolimus
date: 2012-02-22
pages: 3
extension: .pdf
mime: application/pdf
words: 1828
sentence: 125
flesch: 57
cache: cache/dr-3013.pdf
txt: txt/dr-3013.txt
summary:
  In next 1-2 years, she developed small erythematous lesions, which expressed clear and sometimes, hemorrhagic fluid on excoriation, on the central face. Discussion GRN is an inflammatory condition involving eccrine sweat glands of nose, cheeks and


id: dr-1949
author: Bouchard, Susan Michele; Mohr, Melinda; Pariser, Robert
title: Taxane-induced morphea in a patient with CREST syndrome
date: 2010-07-20
pages: 2
extension: .pdf
mime: application/pdf
words: 1493
sentence: 82
flesch: 46
cache: cache/dr-1949.pdf
txt: txt/dr-1949.txt
summary:
  Alternatively, limited cutaneous SSc is limited to acral cutaneous involvement of the hands, face, feet, and forearms with occasional late visceral (predominately pulmonary) involvement.1 CREST syndrome represents a form of lSSc and is manifested by calcinosis cutis, Raynaud’s phenomenon, esophageal dys- motility, sclerodactyly, and telangiectasias.2 The development of cutaneous sclerosis is typically preceded by tissue inflammation, endothelial cell activation, and edema.3 Histopathological changes include dermal thickening with immense collagen accumula- tion and resulting epidermal atrophy, flattening of rete pegs, and obliteration of hair follicles and sebaceous and sweat glands.2 Inflammatory cells commonly aggregate at the dermal-adi- pose junction, particularly in early lesions.4 Cytokines produced by these inflammatory cells (transforming growth factor-b,2 tumor necrosis factor-a (TNF-a),5,6 interferon gamma (IFN-g),6 and interleukin-6 (IL-6)7) are all present at high levels in the serum of patients with sclero- derma, and are thought to play a central role in the pathogenesis of the disease.8 Several studies have demonstrated an increased incidence of breast and lung cancers in patients with pre-existing SSc. Arthritis Rheum 1977;20:975-84. 5. Sharpe RJ, Margolis RJ, Askari M, et al. Induction of dermal and subcutaneous inflammation by recombinant cachectin tumor necrosis factor (TNF-alpha) in the mouse.


id: dr-2726
author: Tukenmez Demirci, Gulsen; Altunay, Ilknur Kivanc; Sarikaya, Sezgi; Sakiz, Damlanur
date: 2011-11-25
pages: 2
extension: .pdf
mime: application/pdf
words: 1635
sentence: 103
flesch: 55
cache: cache/dr-2726.pdf
txt: txt/dr-2726.txt
title:
  Lupus erythematosus and lichen planus overlap syndrome: a case report with a rapid response to topical corticosteroid therapy

summary:
  Histopathology of the biopsy speci- men from his back which showed thinning of the epidermis, basal layer vacuolar degenera- tion, perifollicular chronic inflammatory infil- trates and deposition of mucin in the dermis was consistent with subacute cutaneous LE. Furthermore, in a study conducted by De Jong et al., with the immunohistochem- ical examination of the markers for extracellu- lar matrix proteins, it was asserted that LE/LP overlap syndrome can be considered as LP-like LE rather than as a distinct disease.7 The lesions on the back in our patient were more consistent with LE clinically and histopatho- logically,while those on his hands were consis- tent with LP clinically and histopathologically.


id: dr-1779
author: Biskup, Edyta; Manfé, Valentina; Kamstrup, Maria; Gniadecki, Robert
title: Growth dynamics and cyclin expression in cutaneous T-cell lymphoma cell lines
date: 2010-05-06
pages: 2
extension: .pdf
mime: application/pdf
words: 1589
sentence: 85
flesch: 61
cache: cache/dr-1779.pdf
txt: txt/dr-1779.txt
summary:
  DR [Dermatology Reports 2010; 2:e8] [page 21] Growth dynamics and cyclin expression in cutaneous T-cell lymphoma cell lines Edyta Biskup,1 Valentina Manfé,1 Maria R. Kamstrup,1 Robert Gniadecki1,2 1Department of Dermatology, Bispebjerg Hospital, Copenhagen; 2Faculty of Health Sciences, University of Copenhagen, Denmark Abstract We have investigated cell growth dynamics and cyclins B1 and E expression in cell lines derived from mycosis fungoides (MyLa), Sézary syndrome (SeAx), and CD30+ lympho- proliferative diseases (Mac1, Mac2a, JK).


id: dr-2900
author: Watkins, Casey E.; Bokor, Winston B.; Leicht, Stuart; Youngberg, George; Krishnaswamy, Guha
title: Telangiectasia Macularis Eruptiva Perstans: more than skin deep
date: 2011-07-29
pages: 8
extension: .pdf
mime: application/pdf
words: 7255
sentence: 458
flesch: 50
cache: cache/dr-2900.pdf
txt: txt/dr-2900.txt
summary:
  Neurologic symptoms and diagnosis in adults with mast cell disease. Development of additional morbidities, such as reactions to bee stings, systemic ana- phylaxis, osteoporosis or bleeding secondary to heparin release from mast cells, may occur and may complicate the diagnosis, unless suspect- ed.4-8 On occasion, the disease may evolve into a hematological malignancy, making early diagnosis, classification and monitoring an essential aspect of disease management.9 This review will discuss the diagnosis, pathology, pathogenesis and mast cell biology as well as the management of TMEP, compli- cated by systemic mastocytosis.


id: dr-2659
date: 2011-07-11
pages: 2
extension: .pdf
mime: application/pdf
words: 1245
sentence: 73
flesch: 39
cache: cache/dr-2659.pdf
txt: txt/dr-2659.txt
author:
  Balato, Anna; Raimondo, Annunziata; Cantelli, Mariateresa; Siano, Maria; Lembo, Serena; Scalvenzi, Massimiliano; Balato, Nicola

title:
  The important role of interdisciplinary collaboration in the management of a melanocytic skin lesion

summary:
  +39.081.7462457 - Fax +39.081.7462442. E-mail: serenalembo@yahoo.it Key words: melanocytic skin lesion, dermoscopy, histopathology, regression, interdisciplinary col- laboration. The knowledge of a dermoscopic pattern which might be pre- dictive of a histopathological difficulty for the analysis of melanocytic skin lesions should be an alert to a meticulous clinical, dermoscopical and histopathological correlation.8


id: dr-2065
author: Raaby, Line; Otkjær, Kristian; Salvskov-Iversen, Maria Luise; Johansen, Claus; Iversen, Lars
date: 2010-10-14
pages: 6
extension: .pdf
mime: application/pdf
words: 5461
sentence: 280
flesch: 56
cache: cache/dr-2065.pdf
txt: txt/dr-2065.txt
title:
  A characterization of the expression of 14-3-3 isoforms in psoriasis, basal cell carcinoma, atopic dermatitis and contact dermatitis

summary:
  Protein expression of TNF-alpha in psori- atic skin is regulated at a posttranscrip- tional level by MAPK-activated protein kinase 2. It is intriguing to speculate that an increased activity of MK2 combined with ele- vated protein expression of 14-3-3τ inhibits the destabilising effect of TTP on TNF-α mRNA thereby promoting TNF-α protein expression, but further studies are needed to clarify this.


id: dr-1966
author: Secher, Lisa Linnea Søholm; Vind-Kezunovic, Dina; Zachariae, Claus Otto Carl
title: Side-effects to the use of laptop computers: erythema ab igne
date: 2010-08-31
pages: 1
extension: .pdf
mime: application/pdf
words: 806
sentence: 51
flesch: 67
cache: cache/dr-1966.pdf
txt: txt/dr-1966.txt
summary:
  We report a case with erythema ab igne on the thigh of a 17-year-old girl, induced by use of laptop computers four to five hours daily for nine months. [page 27] Side-effects to the use of laptop computers: erythema ab igne Lisa Linnea Søholm Secher, Dina Vind-Kezunovic, Claus Otto Carl Zachariae Department of Dermatology, Copenhagen University Hospital Gentofte,


id: dr-2579
author: Sachdeva, Silonie
title: Ulcerated cutaneous epithelioid hemangioendothelioma in an 8-month old infant
date: 2011-10-19
pages: 2
extension: .pdf
mime: application/pdf
words: 1206
sentence: 77
flesch: 54
cache: cache/dr-2579.pdf
txt: txt/dr-2579.txt
summary:
  On the basis of these findings, diagnosis of ulcerated cutaneous epithelioid hemangioendothelioma was made. Besides these endothelial markers, it is advised that analysis of Factor VIIIrAg and alpha smooth-muscle actin which are also important immunohistochemical markers for cutaneous EHE should be done wherever the facility is available.


id: dr-3018
author: Kluger, Nicolas; Mahé, Antoine; Guillot, Bernard
title: Eruptive keloids after chickenpox
date: 2011-07-27
pages: 2
extension: .pdf
mime: application/pdf
words: 898
sentence: 54
flesch: 53
cache: cache/dr-3018.pdf
txt: txt/dr-3018.txt
summary:
  Herein we report a dramatic case in a 4-year-old black girl and dis- cuss the issues related to the management of hypertrophic scars and keloids in this peculiar situation. Hypertrophic scars and keloids--a review of their pathophysiology, risk factors, and therapeutic management.


id: dr-3012
author: Topal, Firdevs; Senel, Engin; Akbulut, Sabiye; Topal, Fatih; Dolek, Yasemin
date: 2011-09-15
pages: 2
extension: .pdf
mime: application/pdf
words: 856
sentence: 54
flesch: 49
cache: cache/dr-3012.pdf
txt: txt/dr-3012.txt
title:
  A new combination of multiple autoimmune syndrome? Coexistence of vitiligo, autoimmune thyroid disease and ulcerative colitis

summary:
  The pathogenesis of multiple autoimmune syndrome is not known yet and environmental triggers and genetic susceptibility have been suggested to be in- volved. +90.376.2131098. E-mail: enginsenel@enginsenel.com Key words: multiple autoimmune syndrome, autoimmunity, vitiligo, ulcerative colitis, autoim- mune thyroiditis.


id: dr-2854
author: Dyring-Andersen, Beatrice; Skov, Lone; Jensen, Peter
title: Chronic lymphoedema caused by recurrent infections in a patient with allergic hand eczema
date: 2011-07-11
pages: 1
extension: .pdf
mime: application/pdf
words: 935
sentence: 54
flesch: 49
cache: cache/dr-2854.pdf
txt: txt/dr-2854.txt
summary:
  The problem of chronic lymphoedema follow- ing allergic contact dermatitis has been infre- quently reported.1-5 Case Report We report a case of a 47-year-old woman with severe allergic contact dermatitis compli- cated by chronic lymphoedema. Unusual complica- tion of allergic contact dermatitis of the hands -- recurrent lymphangitis and per- sistent lymphoedema.


id: dr-2272
author: Al Aboud, Khalid Mohammad
title: Becker nevus on the neck with ear involvement
date: 2011-02-28
pages: 1
extension: .pdf
mime: application/pdf
words: 508
sentence: 38
flesch: 70
cache: cache/dr-2272.pdf
txt: txt/dr-2272.txt
summary:
  Al Aboud K, Al Hawsawi K. Becker nevus on the hand. E-mail: amoa65@hotmail.com Key words: Becker nevus, head, skin.


id: dr-2762
author: George, Leni; Agrawal, Nisha; Hogan, Peter
title: Focal dermal hypoplasia in a male
date: 2011-07-01
pages: 2
extension: .pdf
mime: application/pdf
words: 904
sentence: 57
flesch: 57
cache: cache/dr-2762.pdf
txt: txt/dr-2762.txt
summary:
  PORCN gene mutations and the protean nature of focal dermal hypoplasia. Key words: focal dermal hypoplasia, mosaicism, postzygotic mutation. Received for publication: 12 June 2011.


id: dr-1692
author: Wojdylo, Malgorzata Sokolowska; Trzeciak, Magdalena; Roszkiewicz, Jadwiga
title: 2-chlorodeoxyadenosine treatment for cutaneous T-cell lymphoma
date: 2010-09-02
pages: 4
extension: .pdf
mime: application/pdf
words: 1209
sentence: 63
flesch: 62
cache: cache/dr-1692.pdf
txt: txt/dr-1692.txt
summary:
  Partial No response (%) of patients remission remission (%) Bouwhius et al., 2002, USA3 6 13 50 37 Kuzel et al., 1996, USA12 21 14 14 72 Saven et al., 1992, Canada25 16 20 27 47 Rummel et al., 1998, Germany20 66 38 ND ND Kay et al., 1992, Canada9 40 20 22.5 57.5 Kong et al., 1997, USA11 24 12 12 76 O’Brien et al., 1994, USA23 22 18 23 59 Dept. of Dermatology, Poland 6 33 50 17 (present report) ND, no data. Immediate *The time of side effects’ appearance: immediate, hours; early, days, weeks; distant, weeks, months; late, months, years.


id: dr-1469
author: Zhang, Xi-Bao; Li, Chang-Xing; He, Yu-Qing; Zhang, San-Quan; Cai, Yan-Xia
title: Proteus syndrome: a case report and a case study review in China
date: 2010-02-10
pages: 3
extension: .pdf
mime: application/pdf
words: 2584
sentence: 130
flesch: 69
cache: cache/dr-1469.pdf
txt: txt/dr-1469.txt
summary:
  Visceral anomalies such as spleno - megaly, asymmetric megalencephaly, white- matter abnormalities, and nephromegaly as well as masses other than fatty, muscular, and vascular malformations are less common.10 The diagnosis of PS was based on published criteria.4 The current situation of investiga- tion on Proteus syndrome in China All 8 patients reported11-18 in China had at least 2 different skin abnormalities and had other abnormalities, including lipomas, telang- iectatic nevi or other vascular lesions, plantar cerebriform connective tissue nevi, or linear lesions of an epidermal nevus. No n- co mm er cia l u se on ly [Dermatology Reports 2010; 2:e3] [page 7] patients with PS has been confirmed by the identification of a de novo PTEN mutation in a patient with classical PS conforming to the cri- teria described by Biesecker et al.4 Manifestations of Proteus syndrome PS is a rare and sporadic disorder that caus- es postnatal overgrowth of multiple tissues in a mosaic pattern.5


id: dr-1353
author: Raiko, Laura; Leinonen, Pekka; Hägg, Päivi; Peltonen, Juha; Oikarinen, Aarne; Peltonen, Sirkku
title: Tight junctions in Hailey-Hailey and Darier’s diseases
date: 2009-11-13
pages: 5
extension: .pdf
mime: application/pdf
words: 4273
sentence: 207
flesch: 52
cache: cache/dr-1353.pdf
txt: txt/dr-1353.txt
summary:
  The co-localization of TJ proteins with β-catenin, desmoplakin, and E-cadherin in acantholytic cells was studied in more detail in the HHD lesions (Figure 3). Acantholytic cells in Hailey-Hailey disease (HHD) lesions, double immunola- beled for TJ proteins and adherens junction or desmosomal components.


id: dr-1243
author: Gånemo, Agneta
title: Quality of life in Swedish children with congenital ichthyosis
date: 2010-05-18
pages: 3
extension: .pdf
mime: application/pdf
words: 2431
sentence: 126
flesch: 60
cache: cache/dr-1243.pdf
txt: txt/dr-1243.txt
summary:
  The aim of the present study was to investigate QoL in Swedish children with different forms of congenital ichthyosis and also the impact of the children’s disease on the QoL of their fam- ilies. Little is known about the quality of life in children with congenital ichthyosis and the impact of the disease on their family.


id: dr-2434
author: Ibler, Kristina; Jemec, Gregor B.E.
title: Cumulative life damage in dermatology
date: 2011-04-12
pages: 3
extension: .pdf
mime: application/pdf
words: 2663
sentence: 134
flesch: 54
cache: cache/dr-2434.pdf
txt: txt/dr-2434.txt
summary:
  Stigma as well as socialisation are therefore important factors when assess- ing the impact of skin disease on patients. In addition to these psychosocial consequences of skin disease, dermatological conditions fre- quently have symptoms that are difficult to control adequately influencing the resources of the patients negatively.


id: dr-2722
author: Marcus, Eva; Demmler, Diana; Rudolph, Andreas; Fischer, Matthias
title: Bacterial colonization of psoriasis plaques. Is it relevant?
date: 2011-08-05
pages: 2
extension: .pdf
mime: application/pdf
words: 1052
sentence: 66
flesch: 46
cache: cache/dr-2722.pdf
txt: txt/dr-2722.txt
summary:
  Bacterial colonization of psoriasis plaques could be relevant in individ- ual cases. Additional investigations are needed to bet- ter estimate the clinical relevance of coloniza- tion and potential breaches of the innate immune system in psoriasis patients.


id: dr-3332
author: Teixeira, Vera; Vieira, Ricardo; Figueiredo, Américo
title: Tegafur-induced acral hyperpigmentation
date: 2011-09-30
pages: 1
extension: .pdf
mime: application/pdf
words: 663
sentence: 42
flesch: 50
cache: cache/dr-3332.pdf
txt: txt/dr-3332.txt
summary:
  Jucglà A, Sais G, Navarro M, et al. Palmo- plantar keratoderma secondary to chronic acral erythema due to tegafur. DR [page 68] [Dermatology Reports 2011; 3:e30] Tegafur-induced acral hyperpigmentation Vera Teixeira, Ricardo Vieira, Américo Figueiredo Department of Dermatology, Coimbra University Hospital, Portugal Abstract Tegafur is a prodrug of 5-fluorouracil (5-FU) with a similar spectrum of antitumor activity.


id: dr-3351
title: Ellagic acid inhibits melanoma growth in vitro
date: 2011-12-12
pages: 4
extension: .pdf
mime: application/pdf
words: 3292
sentence: 170
flesch: 56
cache: cache/dr-3351.pdf
txt: txt/dr-3351.txt
author:
  Jensen, James Daniel; Dunn, Jeffrey H.; Luo, Yuchun; Liu, Weimin; Fujita, Mayumi; Dellavalle, Robert P.

summary:
  In addition, ellagic acid promoted G1 cell cycle arrest, increased levels of apoptosis and decreased synthesis of IL-1β and IL-8 in melanoma cells. Ellagic acid also decreased NF-κβ activity, suggesting at least one poten- tial mechanism by which ellagic acid may exert its effects in melanoma cells.


id: dr-3528
author: Smit, Jesper; Poulsen, Jakob Lykke; Sølling, Jakob; Mikkelsen, Carsten Sauer
title: Wegener´s granulomatosis in a young patient preceded by localized cutaneous manifestations
date: 2011-10-27
pages: 2
extension: .pdf
mime: application/pdf
words: 1635
sentence: 69
flesch: 41
cache: cache/dr-3528.pdf
txt: txt/dr-3528.txt
summary:
  As in our case, the clinical course of WG is characterized by an initial or localized phase which may affect any organ followed by a gen- eralized or systemic phase in approximately 80% of cases.1,3 However, in most patients spe- cific cutaneous findings develop concurrently or after the onset of systemic involvement and affect the head or extremities,5 but in our case they were confined to the truncus and preced- ed systemic symptoms and signs, which has only seldomly been described.6 In WG specific cutaneous lesions are seen in approximately 15% of cases,5,6 and are usually associated with renal disease and muscu- loskeletal affection, but this was not noted in our patient. Discussion Our patient initially presented with a local- ized rash on the truncus, but his condition was insidiously complicated by malaise, fever and progression of the cutaneous lesions, and ulti- mately a diagnosis of systemic WG was estab- lished.


id: dr-3831
author: Wollina, Uwe; Schreiber, Andreas; Merla, Knut; Haroske, Gunter
date: 2011-12-13
pages: 5
extension: .pdf
mime: application/pdf
words: 4075
sentence: 244
flesch: 56
cache: cache/dr-3831.pdf
txt: txt/dr-3831.txt
title:
  Combined cetuximab and volumetric modulated arc-radiotherapy in advanced recurrent squamous cell carcinoma of the scalp

summary:
  Case reports of cutaneous Squamous cell carcinoma treated with cetuximab. Schmitt J, Seidler A, Diepgen TL, Bauer A. Occupational ultraviolet light exposure increases the risk for the development of cutaneous squamous cell carcinoma: a systematic review and meta-analysis.


id: dr-3953
author: Jensen, Lisbeth; Stensgaard, Anette; Andersen, Klaus Ejner
title: Psoralen plus ultraviolet A (PUVA) soaks and UVB TL01 treatment for chronic hand dermatoses
date: 2012-02-07
pages: 6
extension: .pdf
mime: application/pdf
words: 5573
sentence: 303
flesch: 65
cache: cache/dr-3953.pdf
txt: txt/dr-3953.txt
summary:
  A study by Lerbaek et al. found that 68% (96/142) still suffer from hand eczema at a follow up study 8 years later.7 Other studies show if the patient has got one contact allergy, his risk of getting more contact allergies, a more severe hand eczema and a worse progno- sis is increased.8,9 Agner et al. found that patients allergic to Compositae and rubber chemicals had the most severe hand eczema, and patients allergic to Compositae, cobolt or paraphenylendiamine (PPD) had the lowest quality of life.9 This suggested that patients allergic to Compositae had the worst hand eczema and their life quality is severely affect- ed. Further, a sub- group of patients suffering from multiple con- tact allergies and Compositae allergy was inter- viewed to explore how their quality of life was influenced by the allergies and hand eczema in order to optimize the service provided by health professionals (Table 1).


id: dr-4313
author: Arvesen, Kristian Bakke; Mikkelsen, Carsten Sauer; Steiniche, Torben; Stausbøl-Grøn, Birgitte
title: Dermatofibrosarcoma protuberans diagnosed by a single biopsy
date: 2012-07-26
pages: 2
extension: .pdf
mime: application/pdf
words: 1052
sentence: 68
flesch: 58
cache: cache/dr-4313.pdf
txt: txt/dr-4313.txt
summary:
  The mortality is high with metastasis, the majority of patients die within the 2 first years.1 Without metastasis and with total sur- gical tumor resection, the prognosis is good with 5 year survival rate of 93-100%.1-4 The recurrence rate is up to 50-75%, most of them within 3 years.1-3 The treatment for DFSP is tumor resection with pathologically negative margins. Adjuvant radiotherapy is not commonly pre- ferred, because of reported cases with growth of aggressive fibrosarcomas in areas with DFSP that were treated with radiation therapy.1 References 1.


id: dr-4976
title: Late reaction to ustekinumab infusion
date: 2013-09-09
pages: 2
extension: .pdf
mime: application/pdf
words: 1444
sentence: 74
flesch: 53
cache: cache/dr-4976.pdf
txt: txt/dr-4976.txt
author:
  Morais, Marina Resener; Meneghello, Luana Pizarro; de Oliveira, Carina Flores; Carvalho, André Vicente Esteves

summary:
  Typically, psoriasis patients will usually cycle through therapies and sometimes will require indefinite treatment.1 In the psoriasis pathophysiology, IL-12 acti- vates CD4 T cells and natural killer cells that induce the production of type 1 cytokines (TNF interferon alpha), while IL-23 stimulates the proliferation and increases the half-life of T cells, which produce IL-17. Baert F, Noman M, Vermeire S, et al. Influence of immunogenicity on the long- term efficacy of infliximab in Crohn’s dis- ease.


id: dr-5113
author: Audhya, Moutusi; Varughese, Jenny S.; Nakhwa, Yuti C.
title: Verrucous lichen planus: a rare presentation of a common condition
date: 2014-05-13
pages: 2
extension: .pdf
mime: application/pdf
words: 1168
sentence: 84
flesch: 54
cache: cache/dr-5113.pdf
txt: txt/dr-5113.txt
summary:
  It is associated with oxidative stress, certain medications and diseases, how- ever the underlying pathology is not exactly known.2 Lichen planus may be divided morphologi- cally into the following types: annular lichen planus, linear lichen planus, hypertrophic lichen planus, atrophic lichen planus, vesicu- lobullous lichen planus, ulcerative lichen planus, follicular lichen planus, actinic lichen planus and lichen planus pigmentosus.3 According to the site of involvement there is lichen planus of the palms and soles (palmo- plantar lichen planus), mucosal lichen planus, lichen planus of the nails, lichen planus of the scalp (leading to cicatricial alopecia), inverse lichen planus.3 Hypertrophic lichen planus/ver- rucosa is one of the relatively rare clinical vari- ants. Herein, we report a very unusual presentation of hypertrophic lichen planus.


id: dr-5282
author: Ruiz Beguerie, Julieta; Gonzalez, Silvina
title: Angina bullosa hemorrhagica: report of 11 cases
date: 2014-05-12
pages: 3
extension: .pdf
mime: application/pdf
words: 1788
sentence: 127
flesch: 58
cache: cache/dr-5282.pdf
txt: txt/dr-5282.txt
summary:
  Oral Surg Oral Med Oral Pathol 1987; 63:560-5. 7. +54.1230.448.2000 E-mail: jruiz@cas.austral.edu.ar Key words: angina bullosa haemorrhagica, bul- lous hemorrhagica, oral mucosa blisters.


id: dr-3036
title: Pseudolymphoma tattoo-induced
date: 2011-11-29
pages: 2
extension: .pdf
mime: application/pdf
words: 1178
sentence: 65
flesch: 48
cache: cache/dr-3036.pdf
txt: txt/dr-3036.txt
author:
  Pasolini, Giorgio; Ghidini, Patrizia; Arisi, Mariachiara; Pedretti, Alessandra; Ungari, Marco; Calzavara Pinton, Piergiacomo

summary:
  Patch tests with the Standard series recom- mended by the Italian Society of Occupational and Environmental Allergological Dermatology (SIDAPA) and with substances often present into tattoo dyes (ammonium chloride mercury, sulphate mercury (cinnabar), cadmium, cop- per, titanium, iron, chromium sulphate, chromium chloride, 2-[ethyl[4-[(4-nitro- phenyl)azo]phenyl]amino],4-(4-Nitrophen ylazo)aniline, Ethyl (2-mercaptobenzoato-S) mercury sodium salt, paraphenylendiamine ) showed a strong erythematous vesicular reac- tion (3+) to ammonium chloride mercury, cinnabar and Thimerosal after 48 hours. The patient was otherwise in good health and he had no personal or family history of allergic diseases or contact dermatitis.


id: dr-5498
author: Gowda, Kiran Krishne; Agarwal, Parimal; Bal, Amanjit
title: Mucinous eccrine carcinoma of the eyelid: re-emphasizing the need for awareness of rare lesions
date: 2014-09-02
pages: 2
extension: .pdf
mime: application/pdf
words: 1498
sentence: 88
flesch: 49
cache: cache/dr-5498.pdf
txt: txt/dr-5498.txt
summary:
  DR [page 12] [Dermatology Reports 2014; 6:5498] Mucinous eccrine carcinoma of the eyelid: re-emphasizing the need for awareness of rare lesions Kiran Krishne Gowda, Parimal Agarwal, Amanjit Bal Department of Histopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India Abstract We report here the case of a man presenting with mucinous eccrine carcinoma (MEC) involving eyelid. Surgery is the treatment of choice as mucinous eccrine carcinoma is resistant to radiotherapy and chemotherapy.


id: dr-5712
author: Chan, Wai Sze Agnes; Tee, Shang-Ian; Chandran, Nisha Su Yien; Pan, Jiun Yit
title: Two episodes of cutaneous non-tuberculous mycobacterial infection in a patient with psoriasis
date: 2015-06-15
pages: 3
extension: .pdf
mime: application/pdf
words: 2040
sentence: 111
flesch: 45
cache: cache/dr-5712.pdf
txt: txt/dr-5712.txt
summary:
  Interestingly, she then developed a second episode of cutaneous NTM infection with Mycobacterium haemophilum over the same body region, five years after stoppage of methotrexate. We further discuss the risk factors for cutaneous NTM infection, treatment, and highlight the need for diagnostic vigilance.


id: dr-3057
title: Cutaneous lesions as presentation form of mantle cell lymphoma
date: 2011-12-06
pages: 3
extension: .pdf
mime: application/pdf
words: 1762
sentence: 137
flesch: 62
cache: cache/dr-3057.pdf
txt: txt/dr-3057.txt
author:
  Merino de Paz, Nayra; Rodriguez-Martin, Marina; Contreras Ferrer, Patricia; Garcia-Hernandez, Sonia; Hernandez de Leon, Nieves; Martin-Herrera, Antonio; Noda-Cabrera, Antonio

summary:
  Skin manifestation of mantle cell lymphoma. Most of data adapted from Motegi S, Okada E, Nagai Y, Tamura A, Ishikawa O. Skin manifestation of mantle cell lymphoma.


id: dr-3782
date: 2011-12-01
pages: 3
extension: .pdf
mime: application/pdf
words: 1971
sentence: 114
flesch: 56
cache: cache/dr-3782.pdf
txt: txt/dr-3782.txt
author:
  Weiss, Glen J.; Tibes, Raoul; Blaydorn, Lisa; Jameson, Gayle; Downhour, Molly; White, Erica; Caro, Ivor; Von Hoff, Daniel D.

title:
  Long-term safety, tolerability, and efficacy of vismodegib in two patients with metastatic basal cell carcinoma and basal cell nevus syndrome

summary:
  It is also required to bring the hair folli- cle from the resting to the growth phase.4 Loss of heterozygosity and inactivation muta- tions in PTCH1 and SMO have been implicat- ed in the development of the majority of basal cell carcinomas (BCCs)5-7 and in patients with basal cell nevus syndrome (BCNS).7,8 Vismodegib (GDC-0449) is a synthetic small molecule inhibitor of SMO that blocks down- stream HHSP target genes; it has favorable pharmaceutical properties and greater poten- cy than cyclopamine.9,10 A phase I dose-find- ing, safety, and tolerability study of vismodeg- ib in patients with advanced BCC and solid tumors was conducted, demonstrating prima- rily mild to moderate side effects.6,7 Here we report on our experience of treating two patients with advanced BCC participating in the phase Molly Downhour,1 Erica White,1 Ivor Caro,2 Daniel D. Von Hoff1 1Virginia G. Piper Cancer Center at Scottsdale Healthcare, Scottsdale, AZ, 2Genentech, South San Francisco, CA, USA Abstract Tumor responses in advanced basal cell car- cinoma (BCC) have been observed in clinical trials with vismodegib, a SMO antagonist.


id: dr-3190
author: Caucanas, Marie; Müller, Gebhard; Vanhooteghem, Olivier
title: The appearance of angiolipomatosis after using laptop computer on the thighs: a relationship?
date: 2011-09-09
pages: 2
extension: .pdf
mime: application/pdf
words: 1046
sentence: 72
flesch: 56
cache: cache/dr-3190.pdf
txt: txt/dr-3190.txt
summary:
  Gohar A. Comment on the letter by Bach- meyer, Bensaid and Bégon on laptop computer as a modern cause of erythema ab igne. Laptop computer associated erythema ab igne.


id: dr-3878
author: Maio, Paula; Amaro, Cristina; Rodrigues, Ana; Milheiro, Adelaide; Cardoso, Jorge
title: Zosteriform metastases from colon carcinoma: an unusual pattern
date: 2012-12-18
pages: 2
extension: .pdf
mime: application/pdf
words: 1428
sentence: 93
flesch: 49
cache: cache/dr-3878.pdf
txt: txt/dr-3878.txt
summary:
  The mechanisms that might predispose cer- tain types of internal malignancies to give rise to cutaneous metastasis have rarely been dis- cussed in the literature. In recent years, chemokines and their receptors have been shown to mediate tumorigenesis and the metastasis spreading process.7 One proposal mechanism for cutaneous metastization is the expression of the chemokine receptor CCR10, which is involved in cutaneous metastasis of melanomas by mediating the survival, migration and growth of melanoma cells.


id: dr-3400
author: Ricci, Giampaolo; Bellini, Federica; Dondi, Arianna; Patrizi, Annalisa; Pession, Andrea
title: Atopic dermatitis in adolescence
date: 2011-12-19
pages: 3
extension: .pdf
mime: application/pdf
words: 3020
sentence: 147
flesch: 55
cache: cache/dr-3400.pdf
txt: txt/dr-3400.txt
summary:
  The sex gender also influences the preva- lence of AD: during the first 2 years of life AD more often affects males,6-8 but in the pubertal age and in adulthood the female sex has a higher prevalence;9 no significant differences are reported during the school age. Ziyab and colleagues10 performed a longitu- dinal study in order to evaluate a relationship between variations in AD prevalence, gender and allergic sensitization during the first 18 years of life.


id: dr-3337
author: Ortiz, Arisa E.; Zachary, Christopher B.
title: Laser therapy for Hailey-Hailey Disease: review of the literature and a case report
date: 2011-10-19
pages: 4
extension: .pdf
mime: application/pdf
words: 3854
sentence: 235
flesch: 59
cache: cache/dr-3337.pdf
txt: txt/dr-3337.txt
summary:
  After CO2 laser treatment, the patient remained free of disease in treated areas 8 months after therapy. Increased healing IU time with laser treatment compared to dermabrasion.


id: dr-3084
author: Kaptanoglu, Asli Feride; Yuksel, Ozlem; Ozyurt, Selcuk
title: Plantar pitted keratolysis: a study from non-risk groups
date: 2012-02-07
pages: 3
extension: .pdf
mime: application/pdf
words: 2427
sentence: 151
flesch: 54
cache: cache/dr-3084.pdf
txt: txt/dr-3084.txt
summary:
  Pitted keratolysis is reported to be more common among barefooted laborers/ farmers, sailors, soldiers and industrial work- ers wearing occluded wet shoes for prolonged periods.1 Ramsey reported pitted keratolysis as a common infection of active feet as sporting activity makes the feet hot and wet.10 Patients with a diagnosis other than pitted ker- atolysis were excluded from the study, but 4 of the patients who concomitantly had both tinea pedis and pitted keratolysis were included.


id: dr-4265
author: Pritzier, Ellen Cathrine; Mikkelsen, Carsten Sauer
title: Polymorphic eruption of pregnancy developing postpartum: 2 case reports
date: 2012-06-06
pages: 2
extension: .pdf
mime: application/pdf
words: 1507
sentence: 82
flesch: 52
cache: cache/dr-4265.pdf
txt: txt/dr-4265.txt
summary:
  DR [page 22] [Dermatology Reports 2012; 4:e7] Polymorphic eruption of pregnancy developing postpartum: 2 case reports Ellen Cathrine Pritzier, Carsten Sauer Mikkelsen Department of Dermato-venerology, Stavanger University Hospital, Stavanger, Norway Abstract Polymorphic eruption of pregnancy (PEP), also known as pruritic urticarial papules and plaques of pregnancy, is a common benign der- matosis of pregnancy mainly affecting primi- gravidae and multiple pregnancies. Introduction Polymorphic eruption of pregnancy (PEP), also known as pruritic urticarial papules and plaques of pregnancy (PUPPP) is a common benign dermatosis of pregnancy mainly affect- ing primigravidae and multiple pregnancies.


id: dr-3207
author: Issa, George; Blalock, Travis W.; Lesher, Jack L.
title: Patient with giant Becker’s nevus and epidermal nevus
date: 2011-09-12
pages: 2
extension: .pdf
mime: application/pdf
words: 973
sentence: 50
flesch: 53
cache: cache/dr-3207.pdf
txt: txt/dr-3207.txt
summary:
  This, along with the increased number of terminal hairs seen within many le- sions, and reports of acne vulgaris confined to Becker’s nevi, has raised the suspicion of an- drogenic stimulation as an underlying factor.1 Hypertrichosis is present in approximately one-half of cases and there is often an associ- ated smooth muscle hamartoma.1 Epidermal nevi are congenital hamartomas that arise from pluripotential germinative cells of the basal layer of the embryonic epidermis.3 They appear as patches, plaques, or nodules that may be bilateral and most commonly affect the face, trunk, and proximal extremities.4,5 An estimated one third of affected individuals have involvement of other organs, which is called epidermal nevus syndrome.5 This spo- radic neurocutaneous linkage of congenital ec- Dermatology Reports 2011; volume 3:e23 Correspondence: Travis W. Blalock, MD, Medical College of Georgia, Division of Dermatology, 1004 Chafee Ave., Augusta, GA 30904, USA. E-mail: tblalock@mcg.edu Key words: epidermal nevus, Becker's nevus, epi- dermal nevus syndrome.


id: dr-4918
author: Naccarato, Mark; Yoong, Deborah; Solomon, Robert; Ostrowski, Mario
date: 2013-07-29
pages: 2
extension: .pdf
mime: application/pdf
words: 1840
sentence: 88
flesch: 37
cache: cache/dr-4918.pdf
txt: txt/dr-4918.txt
title:
  Erythema annulare centrifugum-like eruption associated with pegylated interferon treatment for hepatitis C

summary:
  The term erythema annulare centrifugum (EAC) was first introduced by Darier in 1916 to describe an eruption of annular lesions that enlarged rapidly then disappeared in 1 to 2 weeks while new lesions continued to develop.6 EAC lesions usually present as ery- thematous macules or urticarial papules, which enlarge centrifugally and clear centrally, thereby creating an annular appearance.7 As the edges of lesions advance, they may become confluent with adjacent lesions developing arciform segments.7 Darier described the clas- sical histopathologic feature as a dense perivascular sleeve-like lymphocytic infiltrate throughout the thickness of the dermis.6 However since that time, the term EAC has grown to include similar presentations which have an entirely superficial histology lacking the classic sleeve-like arrangement.6 Lesions of superficial EAC, unlike the deep-type, often include scaling along with nonspecific histo- logic findings of mild spongiosis and peraker- atosis.6 Treatment with these two agents has been associated with numerous side effects, which frequently include dermatologic eruptions.


id: dr-5604
author: Vanderbeck, Kaitlin A.; Giroux, Lyne; Murugan, Nirosha J.; Karbowski, Lukasz M.
date: 2014-11-03
pages: 3
extension: .pdf
mime: application/pdf
words: 2175
sentence: 113
flesch: 54
cache: cache/dr-5604.pdf
txt: txt/dr-5604.txt
title:
  Combined therapeutic use of oral alitretinoin and narrowband ultraviolet-B therapy in the treatment of Hailey-Hailey disease

summary:
  Currently, a mono-therapy of oral alitretinoin has maintained remission of the disease for 14 weeks since the beginning of the initial combination alitretinoin and nar- rowband UVB treatment course. She also reported that HHD lesions have previously appeared on her arms, neck, back, abdomen, popliteal regions, and oral mucosa.


id: dr-5039
author: Simonsen, Anne Birgitte; Deleuran, Mette
date: 2014-05-12
pages: 2
extension: .pdf
mime: application/pdf
words: 1792
sentence: 111
flesch: 49
cache: cache/dr-5039.pdf
txt: txt/dr-5039.txt
title:
  Orofacial granulomatosis in children can be the initial manifestation of systemic disease: a presentation of two cases

summary:
  +45.784.50000 E-mail: anbsim@rm.dk Key words: orofacial granulomatosis, children, Chron's disease. Campbell H, Escudier M, Patel P, et al. Distinguishing orofacial granulomatosis from crohn’s disease: two separate disease entities?


id: dr-3161
author: Caucanas, Marie; Müller, Gebhard; Vanhooteghemv, Olivier
title: Vulvar basal cell carcinoma: report of a case involving the mucosa and review of the literature
date: 2011-12-15
pages: 2
extension: .pdf
mime: application/pdf
words: 1774
sentence: 120
flesch: 60
cache: cache/dr-3161.pdf
txt: txt/dr-3161.txt
summary:
  Basal cell carcinoma of the buccal mucosa. Basal cell carcinoma from mucosal surface of lower lip: report of case.


id: dr-3072
author: Loo, Hui Voon; Oon, Hazel H.
title: Flagellate dermatitis following consumption of shiitake mushroom
date: 2011-10-05
pages: 2
extension: .pdf
mime: application/pdf
words: 1722
sentence: 97
flesch: 44
cache: cache/dr-3072.pdf
txt: txt/dr-3072.txt
summary:
  Physical examination revealed extensive flagellate dermatitis on arms, trunk, legs, neck, forehead and some pinpoint pe- techiae on arms (Figure 1). However, in shiitake dermatitis, skin prick and patch tests were mostly negative except for a few cases re- port by Lipper.3 There was a suggestion of possi- bility of UVA photodermatosis by Hanada during which 47% of patients with shiitake dermatitis had reproducible skin lesions to UVA on pho- totesting but not with UVB.5 Histology findings are nonspecific.


id: dr-3229
author: Gurvits, Grigoriy E.; Nord, Jill A.
title: Eczema Herpeticum in Pregnancy
date: 2011-09-29
pages: 1
extension: .pdf
mime: application/pdf
words: 749
sentence: 43
flesch: 53
cache: cache/dr-3229.pdf
txt: txt/dr-3229.txt
summary:
  She was diagnosed with severe impetiginized EH with underlying severe AD. Unrecognized, it may be fatal and viremia in pregnancy may lead to fetal demise and mis- carriage.


id: dr-3203
author: Mola, Federica; Motolese, Alberico
title: Infliximab-induced intertriginous psoriasis in patient with Crohn's desease
date: 2011-10-03
pages: 2
extension: .pdf
mime: application/pdf
words: 1050
sentence: 51
flesch: 45
cache: cache/dr-3203.pdf
txt: txt/dr-3203.txt
summary:
  TNFα inhibitors have become established agents in the treatment of inflammatory dis- eases and have shown to be of great benefit in many inflammatory diseases (rheumatoid arthritis, ankylosing spondylitis, psoriasis or Crohn’s disease).1 Case Report We report a case of unexpected induction of Psoriasis due to the use of intravenous TNFα inhibitor. An expanding literature of experience with anti TNFα associated psoriasis is providing abundant information about this paradoxical effect.


id: dr-3224
author: Hamstra, Ashley; Messina, Michael; Torres, Abel
title: Benign lichenoid keratosis: an off-center fold case
date: 2011-10-19
pages: 2
extension: .pdf
mime: application/pdf
words: 1031
sentence: 62
flesch: 52
cache: cache/dr-3224.pdf
txt: txt/dr-3224.txt
summary:
  Further pathological review was sought from three dermatopathologists, who all interpreted the slides as benign lichenoid keratosis (Figures 1, 2, 3). E-mail: abelt@aol.com Key words: benign lichenoid keratosis, melano- ma, dermoscopy. Received for publication: 10 August 2011.


id: dr-5816
title: Severe scratcher-reaction: an unknown health hazard?
date: 2015-03-27
pages: 3
extension: .pdf
mime: application/pdf
words: 2084
sentence: 113
flesch: 55
cache: cache/dr-5816.pdf
txt: txt/dr-5816.txt
author:
  Mikkelsen, Carsten Sauer; Holmgren, Helene Ringe; Arvesen, Kristian Bakke; Jarjis, Reem Dina; Gunnarsson, Gudjon Leifur

summary:
  After patch-testing patients with tattoo reactions, the study indicates that the putative allergen(s) causing tattoo reactions are formed inside the dermis and external factors like sunlightproduce photochemical cleavage of tattoo pigments in vivo in the skin and may contribute to allergen formation. Tattoo reactions - an epidemic on the surge: a report of 3 cases.


id: dr-5888
author: Jepsen, Malene E.; Gniadecki, Robert
title: Treatment of primary cutaneous anaplastic large cell lymphoma with superficial X-rays
date: 2015-03-16
pages: 2
extension: .pdf
mime: application/pdf
words: 1308
sentence: 68
flesch: 57
cache: cache/dr-5888.pdf
txt: txt/dr-5888.txt
summary:
  E-mail: r.gniadecki@gmail.com Key words: radiotherapy, cutaneous lymphoma. This observation indicates that superficial, low dose X-ray therapy may provide a cost-effective alternative to the traditional 35-45 Gy schedules.


id: dr-6099
author: Elbendary, Amira; El Tawdy, Amira; Zaki, Naglaa; Alfishawy, Mostafa; Rateb, Amr
title: Subclinical onychomycosis in patients with type II diabetes
date: 2015-12-17
pages: 2
extension: .pdf
mime: application/pdf
words: 1684
sentence: 83
flesch: 49
cache: cache/dr-6099.pdf
txt: txt/dr-6099.txt
summary:
  Larger population of type II diabetic patients is needed to be investigated in further studies in order to answer the question: do we need to recommend screening diabetics for subclinical onychomycosis using nail clipping as a diagnos- tic tool in their routine checkup? Scant data about subclinical onychomycosis were reported (Table 2) and might be a finding in a percent of type II diabetic patients espe- cially the uncontrolled ones which can be asso- ciated with tinea pedis and neuropathy.


id: dr-6386
date: 2016-06-15
pages: 2
extension: .pdf
mime: application/pdf
words: 1420
sentence: 87
flesch: 57
cache: cache/dr-6386.pdf
txt: txt/dr-6386.txt
author:
  Feily, Amir; Hosseinpoor, Masoomeh; Bakhti, Ali; Nekuyi, Mohamad; Sobhanian, Saeed; Fathinezhad, Zahra; Sahraei, Reza; Ramirez-Fort, Marigdalia K.

title:
  Digit-length ratios (2D:4D) as a phenotypic indicator of in utero androgen exposure is not prognostic for androgenic alopecia: a descriptive-analytic study of 1200 Iranian men

summary:
  Reza Sahraei,4 Marigdalia K. Ramirez-Fort5 1Department of Dermatology, Jahrom University of Medical Sciences, Jahrom, Iran; 2Hormozgan University of Medical Sciences, Bandarabas, Iran; 3Department of Community Health, Jahrom University of Medical Sciences, Jahrom, Iran; 4Department of Anesthesiology, Jahrom University of Medical Sciences, Jahrom Iran; 5Department of Dermatology, Tufts Medical Center, Boston, MA, USA Abstract The etiology of androgenic alopecia (AGA) involves several factors, including genetics, androgens, age and nutrition. There is a paucity of studies that sys- temically review the possible positive predic- tive value of 2D:4D in the development of AGA.


id: dr-6819
date: 2017-01-04
pages: 4
extension: .pdf
mime: application/pdf
words: 3030
sentence: 135
flesch: 44
cache: cache/dr-6819.pdf
txt: txt/dr-6819.txt
author:
  Gündüz, Özgür; Emeksiz, Mehmet Can; Atasoy, Pınar; Kıdır, Mehtap; Yalçın, Selim; Demirkan, Serkan

title:
  Signet-ring cells in the skin: a case of late-onset cutaneous metastasis of gastric carcinoma and a brief review of histological approach

summary:
  CK20: Epithelial marker (positive staining in colon, small intestine and stomach) EMA (Epithelial membrane antigen): Expressed frequently in adenocarcinomas and menengiomas ER (Estrogen Receptor): Immunohistochemical stain for estrogen receptor, relatively specific for breast cancer, nuclear staining(+) GCDFP- 15 (Gross cystic disease fluid protein-15, Prolactin-induced protein): can be stained immunohistochemically and is considered as a marker of benign and malignant apocrine metaplasia, usually positive in lobular carcinomas with signet ring cells MUC (Mucin): Mucins are a family of high molecular weight, glycosylated proteins produced by epithelial tissues. Cutaneous metastasis of gastric signet ring cell carci- noma masquerading as allergic contact dermatitis.


id: dr-6976
author: Jensen, Anders Bisgaard; Stausbøl-Grøn, Birgitte; Riber-Hansen, Rikke; d’Amore, Francesco
date: 2017-04-20
pages: 4
extension: .pdf
mime: application/pdf
words: 2882
sentence: 142
flesch: 48
cache: cache/dr-6976.pdf
txt: txt/dr-6976.txt
title:
  Ibrutinib-associated skin toxicity: a case of maculopapular rash in a 79-year old Caucasian male patient with relapsed Waldenstrom’s macroglobulinemia and review of the literature

summary:
  In 2015, Ibrutinib was also approved for use in pre-treated adult WM patients, or previously untreated WM patients not eligible for chemotherapy. Data on skin- based toxicity in WM patients are largely lacking, and as of now only a small amount of detailed clinical characteristics of rash in this group of patients have been described.


id: dr-7050
author: Sitek, Jan C.
title: Actinic prurigo in Scandinavian adolescent successfully treated with cyclosporine A
date: 2017-06-01
pages: 2
extension: .pdf
mime: application/pdf
words: 1109
sentence: 68
flesch: 46
cache: cache/dr-7050.pdf
txt: txt/dr-7050.txt
summary:
  Partial decrease in epidermal Langerhans cells in AP patients treated with cyclosporine A has been observed. Cyclosporine A is generally omitted as a therapy option for AP in publications on photodermatoses, including a recent review paper regarding photodermatoses in children.1 We advocate cyclosporine A as a suitable treatment alternative in AP patients demanding systemic intervention.


id: dr-7340
author: Uyanikoglu, Hacer; Aksoy, Mustafa
title: Quality of life in patients with melasma in Turkish women
date: 2017-10-11
pages: 4
extension: .pdf
mime: application/pdf
words: 2960
sentence: 178
flesch: 65
cache: cache/dr-7340.pdf
txt: txt/dr-7340.txt
summary:
  However, unnecessary tests and intensive medical care are not recommended for pregnant women with melasma, in order to avoid fur- ther stress for these patients and because of the transient character of gestational melas- ma.15 The hormonal link to melasma has not been clearly defined; some studies have noted the onset or worsening of disease with pregnancy or OC use.16,17 We observed OC use in 26.7% of our patients, which was consistent with previous studies that showed a prevalence of 8-29% with regard to OC use in melasma patients. Although we did not assess the relationship between OC use and the onset of melasma, we observed that OC use was not associated with melasma severity.


id: dr-7198
author: Moreira, Jorge; Gonçalves, Rita; Coelho, Pedro; Maio, Tiago
title: Eyelid dermatitis caused by allergic contact to acrylates in artificial nails
date: 2017-05-29
pages: 2
extension: .pdf
mime: application/pdf
words: 1430
sentence: 76
flesch: 51
cache: cache/dr-7198.pdf
txt: txt/dr-7198.txt
summary:
  The results were consistent with the diagnosis of allergic contact dermatitis to artificial nails containing acrylates. Classically, ACD caused by acrylates was considered primarily an occupational disease, affecting mainly dentists, prosthesis technicians, painters, and workers in the fiberglass and graphic printing industries.6 In the last few years, with the widespread use of artificial nails, an increasing number of cases of allergic contact dermatitis caused by acry- lates have been reported particularly in nail technicians, but also among artificial nail users.7-9 Exposure to acrylates in artificial nails may induce a wide variety of clinical mani- festations.


id: dr-7445
author: Fıçıcıoğlu, Sezin; Can, Nuray; Tutuğ, Busem
date: 2018-05-14
pages: 3
extension: .pdf
mime: application/pdf
words: 2075
sentence: 105
flesch: 43
cache: cache/dr-7445.pdf
txt: txt/dr-7445.txt
title:
  A case of chronic ulcer due to subcutaneous arteriolosclerosis in an obese patient mimicking pyoderma gangrenosum

summary:
  Martorell hypertensi- ve ischemic leg ulcer; iv) calciphylaxis with normal renal and parathyroid function (eut- rophication) all having the same clinical features as necrotizing livedo, skin infarcti- ons and ulcerations at typical locations. This subcutaneous ischemic arteriolosclerosis is a common pathophysio- logical feature also in Martorell hypertensi- ve ischemic leg ulcer, calciphylaxis in chro- nic renal insufficiency.


id: dr-7660
author: Fesler, Melissa C.; Middelveen, Marianne J.; Stricker, Raphael B.
title: Clinical evaluation of Morgellons disease in a cohort of North American patients
date: 2018-04-24
pages: 4
extension: .pdf
mime: application/pdf
words: 3210
sentence: 218
flesch: 57
cache: cache/dr-7660.pdf
txt: txt/dr-7660.txt
summary:
  Demographic and clinical features of MD patients were analyzed, and laboratory testing for tickborne coinfections and other infectious agents, was performed. Helicobacter pylori was detected in 12% of MD patients.


id: dr-7686
author: DaCunha, Matthew; Moore, Sarah; Kaplan, David
title: Cephalexin-induced acute generalized exanthematous pustulosis
date: 2018-10-01
pages: 2
extension: .pdf
mime: application/pdf
words: 1338
sentence: 76
flesch: 48
cache: cache/dr-7686.pdf
txt: txt/dr-7686.txt
summary:
  Discussion AGEP is a rare adverse reaction with only 3-5 cases per million per year.1-3 Though AGEP is rare, more than 90% of AGEP cases are drug-induced with the most common offenders being beta-lactam antibiotics.1-4 Cephalexin-induced AGEP, however, has only been reported in 3 case reports to our knowledge, making this case a probable 4th case supporting the connec- tion between cephalexin and AGEP.5 Cephalexin is an oral 1st-generation cephalosporin beta-lactam antibiotic that has been shown to have bactericidal activity via the inhibition penicillin-binding pro- teins.6 We report a patient exhibiting a rare adverse effect of cephalex- in: drug-induced Acute Generalized Exanthematous Pustulosis (AGEP).


id: dr-7116
author: Martella, Alessandro; Raichi, Mauro
title: Photoepilation and skin photorejuvenation: an update
date: 2017-06-13
pages: 5
extension: .pdf
mime: application/pdf
words: 4052
sentence: 168
flesch: 51
cache: cache/dr-7116.pdf
txt: txt/dr-7116.txt
summary:
  The range of cutaneous disorders amenable to IPL treatment continues to widen. Even with first-gener- ation IPL devices, improved texture and telangiectasias were reported 4 years after IPL treatment (median, 3 sessions) by, respectively, 83% and 82% of individuals with skin types I-IV; improvements in mot- tled pigmentation persisted in 79% of treat- ed subjects.20


id: dr-6891
author: Vashisht, Deepak; Singh, Jatinder; Baveja, Sukriti; Tiwari, Rohit; Bhatnagar, Anuj
title: Unilateral demodicidosis of face mimicking Hansens disease
date: 2016-12-20
pages: 2
extension: .pdf
mime: application/pdf
words: 1180
sentence: 81
flesch: 47
cache: cache/dr-6891.pdf
txt: txt/dr-6891.txt
summary:
  Section through skin biopsy showing multiple follicular infundibula showing Demodex mites (horizontal arrow). There was no local or systemic risk factor sug- gestive of Demodex infestation.


id: dr-7853
author: Zhang, Yingzhe; Nakamura, Tomoyuki; Furukawa, Fukumi; Muragaki, Yasuteru
date: 2019-01-23
pages: 4
extension: .pdf
mime: application/pdf
words: 3209
sentence: 159
flesch: 57
cache: cache/dr-7853.pdf
txt: txt/dr-7853.txt
title:
  Trps1-deficient transplanted skin gave rise to a substantial amount of hair: Trps1 is unnecessary for hair development

summary:
  We introduce mouse hair follicles as a fascinating model to study the functions of Trps1 in mouse hair growth and pathology. Tel.: 073.447.2300 - Fax: 073.447.2300. E-mail: ymuragak@wakayama-med.ac.jp Key words: Hair follicle; Trps1; Hair develop- ment; Hair shaft.


id: dr-5880
author: Jones, Christopher David; Guiot, Luke; Samy, Mike; Gorman, Mark; Tehrani, Hamid
title: The use of chemotherapeutics for the treatment of keloid scars
date: 2015-05-21
pages: 5
extension: .pdf
mime: application/pdf
words: 5564
sentence: 223
flesch: 45
cache: cache/dr-5880.pdf
txt: txt/dr-5880.txt
summary:
  Many factors such as wound tension, skin pigmentation, genetic predisposition, immunoregulation and skin injury have been implicated in the etiology of keloidogenesis.3,8,9 Research into epithelial-mesenchymal interac- tions between keloid keratinocytes and fibrob- lasts has suggested that the overproduction of numerous growth factors and cytokines, such as transforming growth factor beta (TGF-β), platelet-derived growth factor, vascular endothelial growth factor (VEGF), insulin-like growth factor (IGF), interleukin 1 and 6 (IL-1 and IL-6), interferon beta (INF-β) and tumor necrosis factor alpha (TNF-α) are involved in keloid pathology.4,5,10 In addition, it has also been proposed that abnormalities in the apop- tosis pathway may also be linked to keloid gen- esis; in normal wound healing, apoptosis mediates a reduction in cellularity between granulation tissue and normal scarring.9 Mutations in key apoptosis regulator genes, such as p53, bcl-2 and fas, have been demon- strated in keloid fibroblasts, which resulted in lower rates of apoptosis compared to normal controls.3,9,11 On histopathological examina- tion, keloid scars are composed of thick bun- dles of closely packed type I, III, IV and V colla- gen and dilated vessels, both of which are arranged in a haphazardous manner.9,12 In addition to excessive collagen production, keloid fibroblasts also synthesize more elastin, fibronectin and proteoglycan and show abnor- mal responses to cytokine stimulation com- pared to normal fibroblasts.3,4 With little known regarding the exact patho- physiological events underlying this condition, the management of a keloid scar is clinically challenging. In addition, it also has an inhibitory effect on TGF-β induced expression of the type I collagen gene.16 Consequently, several studies have investigat- ed the potential application of intralesional 5- FU, either as an adjunct to conventional thera- py or as an alternative to it, in preventing keloid development and promoting keloid scar resolution.23,24 Following positive evidence regarding 5- FU’s safety and efficacy in preventing scar for- mation after trabeculectomy surgery, Fitzpatrick began to investigate its use in hypertrophic and keloid scar therapy.


id: dr-6063
author: Baghestani, Shahram; Zare, Shahram; Seddigh, Seyed Hamzeh
title: Severity of depression and anxiety in patients with alopecia areata in Bandar Abbas, Iran
date: 2015-12-22
pages: 3
extension: .pdf
mime: application/pdf
words: 2631
sentence: 153
flesch: 61
cache: cache/dr-6063.pdf
txt: txt/dr-6063.txt
summary:
  Kose O, Sayar K, Ebrinc S. Psychometric assessment of alopecia areata patients before and after dermatological treatment. Our study revealed a high prevalence of anxiety and depression in AA patients.


id: dr-6246
date: 2015-12-17
pages: 5
extension: .pdf
mime: application/pdf
words: 4585
sentence: 231
flesch: 50
cache: cache/dr-6246.pdf
txt: txt/dr-6246.txt
author:
  Rottboell, Louise; de Foenss, Sarah; Thomsen, Kenneth; Christiansen, Helle; Andersen, Stine M.; Dam, Thomas N.; Rosada, Cecilia; Stenderup, Karin

title:
  Exploring valrubicin’s effect on Propionibacterium acnes-induced skin inflammation in vitro and in vivo

summary:
  Similar numbers of P. acnes were injected, however different P. acnes strains were employed. This study aims to investigate valrubicin’s possible use in acne treatment by testing valrubicin’s antibacterial effects against P. acnes and P. acnes-induced skin inflammation in vitro and in vivo.


id: dr-3284
author: Maio, Paula; Carvalho, Rodrigo; Amaro, Cristina; Santos, Raquel; Cardoso, Jorge
date: 2012-05-28
pages: 2
extension: .pdf
mime: application/pdf
words: 1183
sentence: 69
flesch: 49
cache: cache/dr-3284.pdf
txt: txt/dr-3284.txt
title:
  Allergic contact dermatitis from sculptured acrylic nails: special presentation with an airborne pattern

summary:
  In particular, we tested three female patients with allergic contact dermatitis from sculptured acrylic nails. DR [page 20] [Dermatology Reports 2012; 4:e6] Allergic contact dermatitis from sculptured acrylic nails: special presentation with an airborne pattern Paula Maio, Rodrigo Carvalho, Cristina Amaro, Raquel Santos, Jorge Cardoso Contact Dermatitis Unit, Dermatology and Venereology Department, Curry Cabral Hospital, Lisbon, Portugal Abstract Methylmethacrylate was first reported in 1941 as a cause of contact dermatitis.


id: dr-7965
date: 2019-05-09
pages: 5
extension: .pdf
mime: application/pdf
words: 3484
sentence: 192
flesch: 47
cache: cache/dr-7965.pdf
txt: txt/dr-7965.txt
author:
  Dehpouri, Tannaz; Rahmatpour Rokni, Ghasem; Ahangar Narenjbon, Nematollah; Goldust, Mohamad; Yamauchi, Paul S.; Wollina, Uwe; Lotti, Torello; Kircik, Leon; Di Lernia, Vito Giuseppe; Sonthalia, Sidharth; Vojvodic, Aleksandra; Szepietowski, Jacek; Bahadoran, Philippe; Errichetti, Enzo; Cantisani, Carmen; Atzori, Laura; Rezaee, Elham; Kutlubay, Zekayi; Engin, Burhan; Nisticò, Steven; Damiani, Giovanni; Conic, Rosalynn R.Z.; Goren, Andy; Čabrijan, Leo; Tchernev, Georgi

title:
  Evaluation of the glycemic effect of methotrexate in psoriatic arthritis patients with metabolic syndrome: A pilot study

summary:
  However, in a retrospective cohort study, Wu et al. showed that PsO, PsA, and RA patients under treatment with TNF inhibitors associated with MTX dis- played no significant differences in terms of the HbA1c level.35 Solomon et al. reported that there is a non-significantly lower risk of incident diabetes mellitus within patients suffering from PsA, PsO, or RA who were treated with methotrexate without tumor necrosis factor inhibitors or hydroxychloro- quine. ©Copyright T. Dehpouri et al., 2019 Licensee PAGEPress, Italy Dermatology Reports 2019; 11:7965 doi:10.4081/dr.2019.7965


id: dr-5804
author: Ky, Christa; Swasdibutra, Brian; Khademi, Shaadi; Desai, Sheetal; Laquer, Vivian; Grando, Sergei A.
date: 2015-03-16
pages: 4
extension: .pdf
mime: application/pdf
words: 4076
sentence: 190
flesch: 56
cache: cache/dr-5804.pdf
txt: txt/dr-5804.txt
title:
  Efficacy of intravenous immunoglobulin monotherapy in patients with cutaneous lupus erythematosus: results of proof-of-concept study

summary:
  In our patients, the relapse rate was much lower, compared to that reported in the literature for CLE patients. For comparison, in other clinical trials the relapse rate was reported at the range of 70-80%.27-29 Conclusions We can conclude that: i) IVIg monotherapy clearly alleviated symptoms in patients with different clinical forms of CLE resistant to standard treatments, which should justify a multi-center clinical trial on a larger number of patients to ultimately establish the efficacy of IVIg in each clinical form of CLE; ii) three monthly cycles of 2 g/kg/month of IVIg were sufficient to achieve a stable remission, but the symptoms may return, indicating the need for a more extended duration IVIg monothera- py of CLE, by analogy with other mucocuta- neous autoimmune diseases; iii) CLASI-A and Skindex-29 appeared to be the most sensitive objective and subjective, respectively, instru- ments for analysis of clinical efficacy of IVIg in patients with CLE, and, therefore, should be employed for assessment of treatment efficacy in future clinical trials of IVIg in CLE; iv) treat- ment with IVIG dramatically decreases the fre- quency and severity of relapses, compared to some previously tested therapies CLE patients.


id: dr-7399
author: Sriphojanart, Tueboon; Khunkhet, Saranya; Suchonwanit, Poonkiat
date: 2017-11-30
pages: 4
extension: .pdf
mime: application/pdf
words: 3802
sentence: 223
flesch: 53
cache: cache/dr-7399.pdf
txt: txt/dr-7399.txt
title:
  A retrospective comparative study of the efficacy and safety of two regimens of diphenylcyclopropenone in the treatment of recalcitrant alopecia areata

summary:
  The present study reveals the effectiveness and safety of the new treatment protocol, which shortens the duration of DPCP treatment and could represent an alternative regimen. Its mechanism of action is not fully understood, but antigenic competition from induction of contact dermatitis on the scalp is believed to be a possible mechanism.9 For almost 10 years, we have been per- forming DPCP treatment regularly in patients with AA who do not respond to other treatments within the first 6 months.


id: dr-7044
author: Seifi, Bahar; Jalali, Sheida; Heidari, Mohammad
title: Assessment effect of breast milk on diaper dermatitis
date: 2017-03-13
pages: 4
extension: .pdf
mime: application/pdf
words: 3334
sentence: 180
flesch: 59
cache: cache/dr-7044.pdf
txt: txt/dr-7044.txt
summary:
  This study was a clinical trial of 30 infants between 0-12 months of age that were suffering from diaper dermatitis and referred to the Health Centers in Tehran, Iran. Because of positive effects of breast milk on healing of diaper dermatitis, it is proposed that educational programs in health centers should be considered by health officials, and the managers would play a key role in increasing knowledge behavior changes in mothers.


id: dr-6599
author: Arcilla, John; Joe, Daniel; Kim, Johnathan; Kim, Yohanan; Truong, VuAnh N.; Jaipaul, Navin
title: Erythrodermic psoriasis treated with apremilast
date: 2016-09-19
pages: 3
extension: .pdf
mime: application/pdf
words: 1573
sentence: 83
flesch: 44
cache: cache/dr-6599.pdf
txt: txt/dr-6599.txt
summary:
  Most ran- domized clinical trials on psoriasis treatments have excluded less common variants such as the erythrodermic and pustular subtypes.4 In light of this, first-line agents that have been used with variable efficacy include cyclosporine, infliximab, acitretin, and methotrexate.5 Etanercept and combination therapies are second-line alternatives.5 Recently, biologics including ustekinumab and golimumab have also been used with reported efficacy in the treatment of erythrodermic pso- riasis.6,7 Systemic corticosteroids and ultravio- let light therapy are not recommended due to risks of disease exacerbation and photosensi- tivity.5 Choice of therapy should be based on disease severity and patient comorbidities. Introduction We report a case of a 79 year old man with erythrodermic psoriasis successfully treated during the initial response phase with the novel oral small-molecule phosphodiesterase-4 inhibitor apremilast.


id: dr-7597
author: Wiraguna, Anak Agung Gde Putra; Pangkahila, Wimpie; Astawa, I. Nyoman Mantik
title: Antioxidant properties of topical Caulerpa sp. extract on UVB-induced photoaging in mice
date: 2018-10-01
pages: 6
extension: .pdf
mime: application/pdf
words: 3850
sentence: 200
flesch: 53
cache: cache/dr-7597.pdf
txt: txt/dr-7597.txt
summary:
  Polyphenols in seaweed are reported as potent inhibitors of NF-kB and AP-1 activi- ties, which lead to nhibition of MMP-1 expression.20 Our results are corroborated by Hantke et al.’s study, which found a compound containing a combination of vitamin C, E, and polyphenols decrease MMP-1 expression by 40%.21 Our results show no difference between the effects of topical 0.2% and 0.4% Caulerpa sp. extract and topical 0.2% astaxanthin. Profile of collagen expression in Wistar mice dermal tissueThe naive control group did not receive any treatment; the vehicle control received UV irradiation and gel with no active ingredients; Group 2 received UV radiation and 0.02% astaxanthin gel; Group 3 received UV radiation and 0.2% Caulerpa sp. extract gel; Group 4 received UV radiation and 0.4% Caulerpa sp. extract gel.


id: dr-8012
date: 2019-03-29
pages: 3
extension: .pdf
mime: application/pdf
words: 2588
sentence: 156
flesch: 57
cache: cache/dr-8012.pdf
txt: txt/dr-8012.txt
author:
  Mawardi, Prasetyadi; Kalim, Handono; Kalim, Kusworini Handono; Fitri, Loeki Enggar; Mintarjo, Karyono; Mudigdo, Ambar; Oyong, Oyong; Wasita, Brian

title:
  The role of protein-53 amyloid in determining the aggressiveness of basal cell carcinoma regulated by interleukin-6, myeloid cell leukemia-1 and basic fibroblast growth factor

summary:
  Based on the biological aspect BCC, this study has found aggressive BCC (A BCC) is more dominant than nonaggressive BCC (NA BCC) with 65.8% and 34.2 % respec- tively. There was a significant difference in the expression of p53 (p = 0.04), amyloid deposits (p = 0.015), P53 amyloid deposits (p = 0.038), IL-6 (p = 0.040), MCL-1 (p = 0.032), bFGF (p = 0.044) in A BCC com- pared with NA BCC.


id: dr-7749
author: Adalsteinsson, Jonas A.; Pan, Michael; Kaushik, Shivani; Ungar, Jonathan
title: Foscarnet-induced genital lesions: An overview with a case report
date: 2018-06-20
pages: 2
extension: .pdf
mime: application/pdf
words: 1615
sentence: 116
flesch: 57
cache: cache/dr-7749.pdf
txt: txt/dr-7749.txt
summary:
  The fewer cases reported in women can be explained by the fact that between 1990- 1996, foscarnet was mainly used in AIDS affected homosexual males.14-17 Most cases of ulceration have been reported to occur early on in treatment, when high dose regi- mens are used.2 Our patient is an exception given the sudden onset of the ulcers three weeks after initiation of foscarnet therapy. On day 22 of foscarnet treatment, pati- ent complained of painful lesions on his penis (Figure 1).


id: dr-9613
date: 2022-12-29
pages: 19
extension: .pdf
mime: application/pdf
words: 8483
sentence: 384
flesch: 46
cache: cache/dr-9613.pdf
txt: txt/dr-9613.txt
author:
  Burlando, Martina; Campione, Elena; Cuccia, Aldo; Malara, Giovanna; Naldi, Luigi; Prignano, Francesca; Zichichi, Leonardo

title:
  Real-world use of dimehtyl fumarate in patients with plaque psoriasis: a Delphi-based expert consensus

summary:
  In patients with pre-existing clinically relevant infections, the physician should decide whether to initiate DMF therapy once the infection has resolved.5 In patients who develop an infection during DMF treatment, suspension of treatment should be considered and the risk–benefit ratio should be reassessed before re-initiation of therapy.5 DMF is not contraindicated in women of childbearing potential who are using adequate contraception. DMF treatment allows for dosage flexibility and dosage individualization based on patient characteristics and clinical response 9.


id: dr-9625
author: Maalouly, Michele; Saade, Serena; Kurban, Mazen
title: Autoinflammatory diseases: what’s behind them and what’s new. A review
date: 2022-12-29
pages: 21
extension: .pdf
mime: application/pdf
words: 6139
sentence: 419
flesch: 42
cache: cache/dr-9625.pdf
txt: txt/dr-9625.txt
summary:
  Corresponding Author: Michele Maalouly M.D. E-mail address: mm347@aub.edu.lb Phone number: 009613003431 Fax number: 009611745320 Key words: Autoinflammatory diseases, molecular dysregulation, signalosomes. Notably, autoinflammatory diseases are due to hyperactivation of the innate immune system, while autoimmune diseases result from abnormalities of the adaptive immune system.1 Inflammation is a physiological adaptive response to infection and tissue injury.


id: dr-7675
author: Kubanov, Alexey; Gallyamova, Yuliya; Kravchenko, Anzhela
title: Clinical picture, diagnosis and treatment of rosacea, complicated by Demodex mites
date: 2019-03-28
pages: 7
extension: .pdf
mime: application/pdf
words: 6395
sentence: 277
flesch: 49
cache: cache/dr-7675.pdf
txt: txt/dr-7675.txt
summary:
  E-mail: yulya.gallyamova.69@mail.ru Key words: Dermatology life quality index; Demodex mites; Demodex folliculorum; Demodex folliculorum brevis. Our results coin- cide with the results of a study by Moravvej et al., where it was proved that mites play a role in the development of rosacea, stimu- late the formation of an inflammatory pro- cess, which subsequently leads to tissue damage and the formation of telangiec- tasias.18 The data obtained in determining the species belonging to Demodex mites show that Demodex folliculorum is more often detected in the analyses than Demodex bre- vis and Demodex brevis is detected more often than the combined cases are recorded.


id: dr-7916
author: Al-Refu, Khitam
date: 2018-12-21
pages: 7
extension: .pdf
mime: application/pdf
words: 6509
sentence: 329
flesch: 62
cache: cache/dr-7916.pdf
txt: txt/dr-7916.txt
title:
  Dermoscopy is a new diagnostic tool in diagnosis of common hypopigmented macular disease: A descriptive study

summary:
  DR [Dermatology Reports 2019; 11:7916] [page 1] Dermoscopy is a new diagnostic tool in diagnosis of common hypopigmented macular disease: A descriptive study Khitam Al-Refu Faculty of Medicine, Mutah University, Jordan Abstract One of the most frequent complaints in dermatology clinics is the eruption of hypopigmented patchy skin lesions. A pattern of depigmen- tation with residual reservoirs of perifollic- ular pigment have been noted, and this was signifying focally active or regimenting vitiligo.15 This residual perifollicular pig- mentation had been observed in (91.9%) of patients with progressing vitiligo and (62.9%) of those with stable vitiligo,16 and this can be considered as characteristic for vitiligo lesions as it was absent in the non- vitiligo depigmented skin.16


id: dr-8006
date: 2019-06-20
pages: 3
extension: .pdf
mime: application/pdf
words: 2609
sentence: 135
flesch: 52
cache: cache/dr-8006.pdf
txt: txt/dr-8006.txt
author:
  Suwarsa, Oki; Dharmadji, Hartati Purbo; Sutedja, Endang; Herlina, Lengga; Sori, Putri Reno; Hindritiani, Reti; Dwiyana, Reiva Farah; Gunawan, Hendra

title:
  Skin tissue expression and serum level of thymic stromal lymphopoietin in patients with psoriasis vulgaris

summary:
  This study concluded that TSLP levels in the serum of psoriasis vulgaris patients are higher than controls. In this study, we report the skin tissue expressions on lesion- al and non-lesional skin and serum level of TSLP of psoriasis vulgaris patients.


id: dr-9473
author: Sadeghzadeh-Bazargan, Afsaneh; Goodarzi, Azadeh
date: 2023-05-23
extension: .pdf
mime: text/html
words: 16
sentence: 1
flesch: 90
summary: 429 Too Many Requests You have sent too many requests in a given amount of time.
cache: cache/dr-9473.pdf
txt: txt/dr-9473.txt
title:
  Mucocutaneous presentations of consultant critical and non-critical cases of admitted COVID-19 patients, outpatients, and vaccine-associated dermatoses: a clinical atlas and a large original study of two general COVID-19 centers from Iran


# ent

id: dr-3953
sid: 276
eid: 1
type: PRODUCT
entity:
  http://www.photonet.scot.nhs.uk/ documents%20on%20professionals%20pa ge/photonet%20treatment%20protocols%


