



































Sidorov1 – DNADJ


DNA Decipher Journal | May 2012 | Vol. 2 | Issue 2 | pp. 177-205 
Sidorov, L., & Chen, K., Biophysical Mechanisms of Genetic Regulation: Is There a Link to Mind-Body Healing? 

 

 
ISSN: 2159-046X DNA Decipher Journal 

Published by QuantumDream, Inc. 
www.dnadecipher.com 

 

177 

Article 

Biophysical Mechanisms of Genetic Regulation:  

Is There a Link to Mind-Body Healing? 
 

Lian Sidorov
*
 & Kevin Chen 

 

 ABSTRACT 

Over the past several decades, pioneering biophysics work has shown that living tissues interact 

with electric and magnetic fields in unexpected and dramatic ways. From initial anecdotal 

accounts of enhanced healing under electromagnetic stimulation, research in this field has 

progressed to a sophisticated arsenal of investigative tools and theoretical models which include 

polarized light microscopy to study the liquid crystal properties of living cells and laser-

excitation of DNA to induce hybridization through non-molecular information transfer. In almost 

all cases, the results point to a set of remarkable properties of living tissues, and in particular of 

genetic material: the emerging picture is that of biosystems as sources and domains of coherent 

electromagnetic fields, which account for practically instantaneous inter-cellular communication 

and a highly efficient mechanism of energy utilization, and which seem to reflect very closely 

the developmental and patho-physiological state of the organism. In addition, a wide spectrum of 

genetic mechanisms now appears to be under the influence of surrounding electromagnetic 

fields.  

At the same time, an impressive number of studies in the areas of parapsychology and mind-

body medicine converge to show that conscious intent can affect practically every single type of 

genetic program, as well as many physiological parameters [1]. These studies also show that 

such effects can be produced from great distances, and that occasionally they are accompanied 

by unusual energy signatures. Is there a correlation between the effects of electromagnetic fields 

and those of mental intent on genetic regulation and living tissues? This paper will discuss the 

major experimental evidence and proposed mechanisms of these interactions, as well as the 

principal obstacles lying in the way of a viable, comprehensive theory. At the same time, we will 

attempt to formulate several preliminary hypotheses based on this evidence and to sketch some 

possible directions for future research in this field. 

Key Words: genetic control architecture, EMFs, coherence, liquid crystals, interference grids, 

photon polarization, psycho-physiological remodeling, nonlocal communication, topological 

geometrodynamics. 

 
 

 

                                                 
*
 Correspondence: Lian Sidorov, DDS.  http://emergentmind.org E-Mail: liansidorov@gmail.com  

 
Note: This paper is based on a presentation made at the First International Conference on the Science of Whole Person Healing, 
March 28-30, 2003, Washington DC, and was originally published in Journal of Nonlocality & Remote Mental Interactions, Vol. 
4, Issue 1, April 2006. 

http://emergentmind.org/
mailto:liansidorov@gmail.com


DNA Decipher Journal | May 2012 | Vol. 2 | Issue 2 | pp. 177-205 
Sidorov, L., & Chen, K., Biophysical Mechanisms of Genetic Regulation: Is There a Link to Mind-Body Healing? 

 

 
ISSN: 2159-046X DNA Decipher Journal 

Published by QuantumDream, Inc. 
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178 

INTRODUCTION 
 

The history of mind-body medicine in the modern era has been one of continuous struggle 

against both the derisive attitudes of a scientific mainstream firmly embedded into a reductionist, 

materialistic mind frame and the conceptual difficulties of studying something as elusive as the 

contents of consciousness.  While gradual correlations with general factors such as stress have 

lead to the acceptance of psychoneuroimmunology as a legitimate field of study, there is very 

little material in the medical literature about other, more specific effects that mental intent might 

have on the body. 

 

This unfortunate state of affairs, we hope, is about to change. Over the past decade, thousands of 

studies have been conducted all over the world, looking at the interactions between conscious 

intent and living systems - from biomolecules and single celled organisms to human beings - and 

describing statistically significant effects in very concrete, histological and physiological terms. 

These studies, reported in the scientific parapsychology literature as well as in some physics and 

biomedical publications, are part of a rapidly growing body of "human potential science" 

projects - frontier programs funded by governments such as Japan and China to look at 

exceptional human abilities and harness their implications.  Similar studies have also been 

carried out in the US, Russia, Germany and other Western countries, unfortunately under less 

supportive conditions which are generally reflected by their more conservative protocols. A large 

proportion of this material is now available in abstract format through English-language 

publications such as D. Benor's "Spiritual Healing: Scientific Evidence of a Healing Revolution" 

(Vision Publications, 2001 Edition) and the Qigong Institute's Database CD-ROM, updated 

yearly. 

 

In another paper [1], we have reviewed the main classes of studies described in this literature, 

with a focus on genetic functions - showing how practically every major genetic program (from 

DNA replication and cell division rates to gene-specific transcription, translation and 

mutagenesis, to cell differentiation and apoptosis) can be modulated by intent under 

experimental conditions. In this follow-up article, we would like to take the discussion one step 

further and begin to look at a possible mechanism that might account for these startling 

experimental findings. 

 

The present model of genetic control, based on chemical messengers, transcription factors, 

molecular feedback loops, enzyme conformation, promoter regions and other forms of cis-/trans 

modulatory regulation is restricted to describing these all-important programs at a primarily 

intra-cellular level which fails to fully account for the astounding degree of synchronization 

between the billions of cells comprising the human body. It has been shown that on average four 

to eight different transcription factors service each gene's regulatory module and that many 

hundreds to thousands of genes must be coherently expressed in order to create any given tissue 

or multicellular structure [2 - p. 9]. Thus higher-level aspects of growth and development, as well 

as pathological and healing processes, such as the differential spatio-temporal expression of 

DNA in specialized cells and the emergence/loss of complex architecture during embryogenesis 

or malignant growth, are still a matter of heated debate and speculation [3,77]. How does the 

DNA material in each cell respond to its variable environmental circumstances in a way which 



DNA Decipher Journal | May 2012 | Vol. 2 | Issue 2 | pp. 177-205 
Sidorov, L., & Chen, K., Biophysical Mechanisms of Genetic Regulation: Is There a Link to Mind-Body Healing? 

 

 
ISSN: 2159-046X DNA Decipher Journal 

Published by QuantumDream, Inc. 
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179 

reflects the cell's lineage, internal clock and also the activities of thousands of cells in its 

immediate vicinity? Are chemical messengers sufficient to account for the speed and accuracy of 

this large-scale orchestration, or are there higher levels of genetic control architecture yet to be 

discovered?  We believe that sufficient evidence has already accumulated to support the 

existence of such nonlocal, non-molecular controls. We also believe, along with a growing 

number of biophysical research scientists, that the key to the most effective preventive and 

therapeutic health interventions lies in the understanding of genetic regulation at the top levels of 

the control hierarchy - that is, in the way cells communicate with each other, their environment 

and, possibly, with the poorly-understood physical correlates of mental intent. 

 

We have therefore divided this article into several parts: in the first section we will try to 

challenge the strict biomolecular approach to medicine by presenting a number of studies which 

clearly demonstrate that electromagnetic fields play a major role in genetic expression; the 

second part will briefly review the main characteristics of mind-matter interactions with respect 

to living systems; finally the discussion will attempt to draw parallels between the biophysical 

and consciousness-mediated mechanisms and point to theoretical models that  might account for 

the effects of intent on targeted biological structures in a nonlocal framework.  

 

  

 

I. THE EFFECTS OF WEAK EM FIELDS ON GENETIC PROGRAMS 
 

A. CELL DIFFERENTIATION IN ADULT, EMBYONIC AND MALIGNANT STATES 

The work of Rose and Becker (1940s-1970s) 

  

Observing that three major characteristics of malignant cells (cell simplicity, mitotic speed and 

metabolic priority) were also typical of embryonic growth and regeneration, in 1948 Meryl Rose 

conducted a landmark experiment designed to test whether the physiological environment of 

regeneration could take over the controls of tumor cells. After transplanting pieces of frog kidney 

tumor to the limbs of salamanders and watching them grow, he amputated the leg just below or, 

in some cases, right through the tumor mass. As opposed to controls, where the tumor 

metastasized and ended up killing the host, these specimens demonstrated a remarkable 

phenomenon: the tumor cells dedifferentiated more fully as the blastema formed, then 

redifferentiated along with the blastema - thus proving that "the regeneration's guidance system 

could control cancer, too" [4 - p. 217].  Furthermore, replicating experiments conducted in 1962-

1963 by F. Seilern-Aspang and K. Kratochwil at the Austrian Cancer Institute showed that, in 

cases where the primary tumor was in the tail, amputation of the tail below that level (i.e. leaving 

the primary tumor intact) resulted in total disappearance of both the primary mass and all its 

distant metastases as the tail regenerated [4 - p. 220] - thus complete healing of two 

aetiologically-distinct injuries. Although this result was obtained only when  the amputation was 

close to the site of the primary tumor, it demonstrated beyond doubt that the key to such 

"spontaneous remission" was a shift in the tumor's immediate environment - most probably the 

electrical currents in the neuroepidermal junction, which Becker would later prove were the 

initiators of regeneration. 

 



DNA Decipher Journal | May 2012 | Vol. 2 | Issue 2 | pp. 177-205 
Sidorov, L., & Chen, K., Biophysical Mechanisms of Genetic Regulation: Is There a Link to Mind-Body Healing? 

 

 
ISSN: 2159-046X DNA Decipher Journal 

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180 

In 1961, Becker and his team found that applying a very weak current (in the order of a billionth 

of an ampere) to a culture of nucleated frog red blood cells induced complete dedifferentiation in 

the cells, which reactivated their nuclei, lost all hemoglobin and became primitive 

(unspecialized) in the space of four hours [4 - p. 143].   

 

These changes, which were later found in the RBCs of fish and other reptiles, suggested a 

reactivation of the DNA - for once the staining characteristics of the nucleus shifted, the process 

continued even if the current was interrupted. All the changes involved paralleled those found in 

the salamander limb blastemas, demonstrating that the process of regeneration was initiated by 

an endogenous "current of injury". Applying this knowledge to wound healing in mammals, in 

1971 Beckers's team stimulated the bone marrow of rats' amputated forelegs with a 1 

nanoampere current and managed to obtain partial regeneration of the limb, including new, well 

organized bone, cartilage, muscle, blood and nerve tissue: at least ten types of cells had 

differentiated from the blastema, and some specimens even demonstrated the rudiments of finger 

cartilage. [4 - p. 153]  

 

What is the nature of this endogenous current which preoccupied Becker for over three decades? 

Far from being restricted to areas of injury, as originally believed, Becker showed in a series of 

ingenious experiments that the entire body of a living organism was permeated by a weak DC 

current, which furthermore appeared to reverse its polarity as the organism's state of 

consciousness changed from awake to deep sedation/anaesthesia.  By demonstrating the Hall 

effect in the leg of a salamander as it regained consciousness [4 - p. 101], Becker showed that 

this DC potential was a semiconductor current - in other words, that the carriers were electrons in 

a semiconducting lattice.  But to admit the existence of a semiconductor current permeating and 

regulating the brain-body continuum, one must be ready to look for an appropriate substrate. 

Semiconduction requires an ordered molecular structure, such as crystals, in which electrons can 

exist in a delocalized fashion and flow coherently across large distances with minimal dissipation 

of energy - a very different model from the type of conduction associated with neurons. In the 

wet, warm, perpetually-fluctuating environment which is the living organism, what could 

possibly constitute a proper matrix for this type of phenomenon? 

 

 

B.  INTERACTIONS BETWEEN EMFs AND DNA 

EVIDENCE FROM BIOELECTROMAGNETICS LABS (1990s-2003) 

 

Before addressing the nature of semiconduction in living tissues, let us review a few more 

interesting studies which look at the effects of electromagnetic fields on DNA regulation. 

 

In a 2002 study, Tofani et al.. found a statistically significant inhibition of tumor growth (40%) 

and increase in survival time (31%) when mice bearing a subcutaneous human colon 

adenocarcinoma (WiDr) were exposed to 70min/day 5.5mT magnetic fields with 50 Hz 

modulation for 4 weeks; a decrease in tumor cell mitotic index and proliferative activity and 

increase in apoptosis were also observed - with no adverse or abnormal effects [5] 

 



DNA Decipher Journal | May 2012 | Vol. 2 | Issue 2 | pp. 177-205 
Sidorov, L., & Chen, K., Biophysical Mechanisms of Genetic Regulation: Is There a Link to Mind-Body Healing? 

 

 
ISSN: 2159-046X DNA Decipher Journal 

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181 

In a similar study reported by Simko et al.. [6], extremely-low frequency EMFs (0.1-1mT, 50Hz) 

applied continuously for 48-72 hrs resulted in increased micronucleus formation and apoptosis in 

transformed cell lines (human squamous cell carcinoma SCL II), but no adverse effects in 

normal, non-transformed cells. Cell death induction consistent with apoptosis was also reported 

in two transformed cell lines (WiDr human colon adenocarcinoma and MCF-7 human breast 

adenocarcinoma) that were exposed to 1mT magnetic fields modulated by 50Hz ELFs). Cells 

with daily exposure of 70 min. for 4 weeks showed significant tumor growth inhibition (up to 

50%) by the end of treatment. No toxic morphological changes were observed in renewing, 

slowly proliferating or static normal cells. [7]   

 

Zhou et al. [9] have shown that a 72 hr exposure of HL60 cells to 50Hz, 0.1-0.8 mT magnetic 

fields resulted in an increased transcription level for tumor necrosis factor receptor p75 and 

interleukin Il-6Ralpha mRNA expression.  

 

Zhao [10] examined the promotion of DNA synthesis in PDL fibroblasts under exposure to 

0.14T magnetic field for 10, 40, 60, 120 min/day x 1week, comparing these to similar treatments 

every other day. Remarkably, he found that the cellular DNA contents increased proportionally 

with exposure time in the daily-treated samples, while no significant changes were found if the 

treatments occurred on alternate days. He concluded that the magnetic field had a cumulative, 

threshold-dependent and time-delayed effect on DNA synthesis. 

 

Eichwald & Walleczek [11] found that ELF (extremely low frequency) EMFs controlled calcium 

uptake regulation in T lymphocytes:  a bi-phasic response (stimulation / inhibition) was 

identified depending on the degree of cellular activation. The authors also noted that this, in turn, 

may affect other cellular processes that are Ca dependent – i.e. DNA synthesis. 

 

Sontag & Dertinger [12] reported that human promyelocytes (HL-60) exposed for 5 minutes to 

an amplitude-modulated, 4000 kHz interferential current (25, 250 and 2500 microA/cm^2) 

showed windows of significant stimulation and depression in intracellular cAMP within the 

range of frequencies studied (0-125 Hz). 

 

In a study by Kubinyi et al.., t-RNA synthetase activity isolated from the brain and liver of mice 

exposed to microwave radiation (2.45 GHz) during gestation showed a decrease after continuous 

wave exposure, and an increase in activity after amplitude-modulated irradiation [13]. 

 

It is interesting to note that many of these studies specifically report finding no adverse effects on 

normal cells exposed to the same EM fields. 

 

Finally, Blank and Soo [14] reviewed evidence that EM fields interact with the activity of the 

cell membrane enzymes Na,K-ATPase and cytochrome oxidase in a frequency-dependent 

manner - but argued that, in addition, large electron flows known to exist within the stacked base 

pairs of DNA could interact directly with EM currents and lead to gene activation [15]. One 

finding that supports this contention is that DNA transcription in cell-free solutions can be 

activated by electromagnetic fields [16]. 

 



DNA Decipher Journal | May 2012 | Vol. 2 | Issue 2 | pp. 177-205 
Sidorov, L., & Chen, K., Biophysical Mechanisms of Genetic Regulation: Is There a Link to Mind-Body Healing? 

 

 
ISSN: 2159-046X DNA Decipher Journal 

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182 

C. ENDOGENOUS COHERENT FIELDS: BIOSYSTEMS AS DYNAMIC HOLOGRAMS 

EVIDENCE FROM THE INTERNATIONAL INSTITUTE OF BIOPHYSICS (1970s-2003) 

 

All living systems emit light spontaneously:  these ultra-weak emissions range from a few up to 

several hundred photons per second per square centimeter of surface area. The distribution 

spectrum ranges from infra-red to ultra-violet and is nearly flat, which indicates that the energy  

is emitted from a wide range of excited molecules and stored in a delocalized manner within the 

system. Based on the characteristics of these emissions, Popp and others [17, 18] have shown 

that the source of the biophotons is a coherent photon field within the organism. The dominating 

role of source and sink for the biophoton field is the DNA molecule [17, 24] (in fact the 

mammalian red blood cells, which do not have active chromatine, are the only cells which do not 

emit biophotons).  

 

Photon fluxes play a remarkable number of biological roles as either carriers of information (in 

enzyme activation, phototropism, photomorphogenesis, phototaxis, regulation of gene 

expression, vision) or as a driving energy for biological processes [21]. Furthermore, it is known 

that both the intensity and the spectrum of the biophoton emission  are strongly correlated with 

the physiological and developmental state of the organism: for example, [22, 23, 25] report  

significantly higher levels of photon emission from surgically removed tumors compared to 

normal tissues, a non-linear correlation between BPE and growth rate, and further correlations 

between the ultra-weak light from the fingertips of patients and their age and certain 

physiopathological states.  These findings offer ample support to the thesis that biophotons are 

intimately related to the regulation of critical biological functions.    

 

Noting correlations between optical properties of molecules and their carcinogenic activity, Popp 

has suggested that cancer induction is related to the loss of coherence of a photon field in the 

living tissues, originating from excited states of DNA [26, 27]. Growth regulation is based on the 

death rate of cells, with sudden cell death and mitosis having to balance each other perfectly. 

With 10^7 cells dying every second in the human body, this information has to travel a distance 

of at least 10^-3 cm in 10^-7 seconds, which is much faster than the velocity of messenger 

molecules, approaching the velocity of sound. If it is assumed that the message is holistic and 

"communicated" to the entire body, then the scale becomes 1 meter, and the speed of 

transmission reaches electromagnetic values. Thus cancer can be seen as an imbalance between 

cell growth and death due to a deterioration of intercellular and full-body communication 

systems [17] - and indeed, research has shown [25] that the characteristics of biophoton emission 

curves are different for normal versus tumor tissues. 

 

The spatio-temporal coherence of biophoton fields means that complex electromagnetic (EM) 

interference patterns are created throughout the organism: the more coherent the light, the 

sharper the interference patterns. It has been suggested by Popp, Gariaev and others  that these 

patterns may be the basis of morphogenesis and structural/biochemical regulation of the 

organism throughout its life - an EM blueprint guiding the development, repair and even social 

behavior of  organisms. The phase information within and between cells is hypothesized to act as 

a biological control parameter regulating the growth and differentiation of cells, with 

constructive interference domains intra-cellularly and destructive interference in the extra-



DNA Decipher Journal | May 2012 | Vol. 2 | Issue 2 | pp. 177-205 
Sidorov, L., & Chen, K., Biophysical Mechanisms of Genetic Regulation: Is There a Link to Mind-Body Healing? 

 

 
ISSN: 2159-046X DNA Decipher Journal 

Published by QuantumDream, Inc. 
www.dnadecipher.com 

 

183 

cellular matrix [24].  Experimental evidence such as the phantom leaf effect [28], the delayed 

luminescence function of tumor cells and the distribution of Daphnia larvae [29, 30, 18] certainly 

seem to support this hypothesis. 

 

One of the most remarkable findings to shed some light on the possible mechanism of biophoton 

control comes from Ho's laboratory: in 1993, she and Lawrence discovered that, under polarized 

light microscopy, the extraordinary level of molecular coherence makes organisms appear 

crystalline. This dynamic coherence is a continuum that extends from intracellular molecules to 

the cytoplasm, extracellular matrix and the connective tissues throughout the organism [18]. The 

lipids in cellular membranes, the cytoskeletal and muscle proteins, collagen and other connective 

tissue macromolecules, as well as the DNA in chromosomes - all these essential and ubiquitous 

molecules of living systems are liquid crystals [31, 32]. Consequently, the organism may be seen 

as a solid state possessing many of the physical characteristics of these highly interesting 

materials. 

 

Liquid crystals (LCs) are mesophases - states of matter between the solid and liquid phase. While 

they possesss long range orientational order, they are highly mobile and responsive, undergoing 

orientation changes (phase transitions) when exposed to a wide variety of stimuli, including 

electromagnetic fields, temperature and pressure changes, hydration, pH, concentrations of 

inorganic ions and other psysico-chemical parameters [31, 32]. LC can convert information 

about minute changes in pressure, temperature and light into electrical currents (they are 

piezoelectric, pyroelectric and photoelectric). Finally, they are permanently modified (sensitized) 

by the passage of electrical currents so as to facilitate the future passage of such currents [4 -p. 

257). 

 

Considering these arguments, Mae-Wan Ho suggests that the LC matrix may act as a quantum 

holographic medium which records interference patterns between local events and the global 

body field - an idea which finds full agreement with Gariaev's experimental work [33]. 

  

 

 

D. EVIDENCE FROM THE RUSSIAN ACADEMY OF SCIENCES 

GARIAEV's DNA-wave BIOCOMPUTER (1990s-2003) 

 

Since the early '90s, Peter Gariaev's team has been developing a new theoretical and 

experimental approach to the study of genetic material encoding and expression. In a pioneering 

series of papers [28, 34, 35, 36, 37, 38], he and his colleagues challenge the limits of the genetic 

code triplet model and propose instead a dual, substantive/wave basis for the encoding and 

expression of genetic material. The wave-like, non-local aspect of genetic regulation is recorded 

at the polarization level of DNA-associated photons, and the genome is seen as a quasi-hologram 

of light and radio waves which creates the background necessary for the appropriate expression 

of genetic material. 

 

Some of the experimental evidence cited in support of this new model is listed below: 

 



DNA Decipher Journal | May 2012 | Vol. 2 | Issue 2 | pp. 177-205 
Sidorov, L., & Chen, K., Biophysical Mechanisms of Genetic Regulation: Is There a Link to Mind-Body Healing? 

 

 
ISSN: 2159-046X DNA Decipher Journal 

Published by QuantumDream, Inc. 
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184 

1.  The existence of homonymous-synonymous ambiguities of genetic texts; 

 

2.  The virus-like strain specificity of prions in the absence of nucleic acid material;  

 

3. The role of introns: statistical analysis using the Zipf-Mandelbrot law reveals that DNA non-

coding sequences, which account for 95-98% of the genome, have more in common with natural 

languages and demonstrate more long-distance correlations than coding sequences; this, 

according to the authors, is a strong indication that non-coding areas are the basis for one or 

more biological languages and represent "a strategic informational content of chromosomes"; 

 

4. The ability of DNA and chromatin in vitro to be pumped  as a laser-active medium for 

subsequent laser light generation; 

 

5. Dzang Kangeng's experiments: successful wave transmission of genetic information from 

donor biosystem to an accepting one via split laser beams fed repeatedly through the optically-

active donor biosystem, then delivered to the receiving biosystem in early developmental stages. 

Mixed characteristics of these non-molecular hybrids (seeds and chicks) were transferred to the  

next generation without need for further irradiation. (Although Kangeng provides no theoretical 

interpretation of the operational device, the authors' previous work with laser mirrors closely 

parallels his protocol, leading them to conclude that the polarized laser beam split into 

orthogonal waves which, by repeated passing through the optically active donor DNA and 

multiple interference with itself, lead to the phenomenon of photon field localization and 

information recording); 

 

6. The authors' similar experiments with polarization-laser-radio-wave (PLRW) spectroscopy, 

whereby they used orthogonally polarized EM beams to repair the genetic information of old 

radioactively-damaged seeds from the Chernobyl area (1987). 

 

The authors argue that the genome emits light and radio-waves whose delocalized interference 

patterns create calibration fields (blueprints) for a system's space-time organization. This 

holographic-type information is being constantly and simultaneously read in billions of cells, 

accounting for the quick coordinated response typical of living systems. Gariaev and his team 

suggest that the genome operates like a "complex multi-wave laser with adjustable frequencies", 

able to produce light and radio waves which regulate the biosystem's space and time 

organization. This complex background is the basis for the correct expression of genetic material 

(peptide codes) during embryogenesis and adult life, accounting for the elusive self-regulation 

and specificity of DNA function in various tissues and under various conditions. Various solitons 

(optical, acoustic, conformational, rotable-oscillating, etc) excited in polynucleotide areas, and 

transmitted over large distances significantly exceeding the hydrogen-bond length, "become the 

apparatus for continual (non-local) reading of context RNA sequences on a whole". 

 

On the basis of this model, the authors suggest that the activation of oncogenes and xenobiotic 

HIV sequences is dependent on genome holographic processes and therefore that future research 

in these high-profile areas should focus on the factors modulating such EM field characteristics 

(such as external artificial modified fields) in addition to local, molecular biology approaches. 



DNA Decipher Journal | May 2012 | Vol. 2 | Issue 2 | pp. 177-205 
Sidorov, L., & Chen, K., Biophysical Mechanisms of Genetic Regulation: Is There a Link to Mind-Body Healing? 

 

 
ISSN: 2159-046X DNA Decipher Journal 

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185 

Given that the expression (onset) of oncogenes and retroviruses such as HIV is known to vary 

widely among individuals and be largely context-specific, the authors suggest that external 

artificial modified fields may, in the future, help us modulate this apparent cellular context 

(environment) and thus keep such noxious genetic material dormant for indefinite periods of 

time. Another interesting suggestion made by Gariaev is that phenomena such as cellular 

apoptosis might be connected with an abnormal compression of photons by cell nuclei, which are 

accumulated to a maximal value and then destroy the nuclei. 

 

Since apoptosis has been frequently demonstrated in healer-treated cancer cultures, and unusual 

electromagnetic signals are also commonly observed during spiritual healing sessions, we would 

like at this point to re-direct our attention and discuss some of the major experimental evidence 

and current conclusions with respect to this phenomenon. 

 

 

  

II. THE EFFECTS OF HEALERS' INTENT ON LIVING TISSUES 
 

In an earlier paper [1] we have described a series of experiments which demonstrate that human 

intentionality can produce a statistically significant effect on the following genetic programs: 

 

 

1. Cell division, reflecting DNA synthesis and mitotic rates 

 

2. Transcription rates and DNA conformation 

 

3. Gene specific translation rates 

 

4. Cell differentiation 

 

5. Mutagenesis 

 

6. Apoptosis, or programmed cell death. 

 

Furthermore, conscious intent has been shown capable (at statistically significant levels) of 

producing the following structural and physiological effects: 

 

1. Conformational changes in cell membrane, chromatin, proteins [1, 78] 

 

2. Distant influence on a target's EEG, heart rate, galvanic skin response, finger blood volume, 

blood pressure, as well as fish orientation and algae motility [40, 41, 42 - p. 336] 

 

These controlled, randomized and typically (but not always) blind studies have been extensively 

discussed in our previous paper – however we shall briefly summarize these results in order to 

highlight certain parallels with the effect of weak EMFs on living tissues, as described earlier. 

 



DNA Decipher Journal | May 2012 | Vol. 2 | Issue 2 | pp. 177-205 
Sidorov, L., & Chen, K., Biophysical Mechanisms of Genetic Regulation: Is There a Link to Mind-Body Healing? 

 

 
ISSN: 2159-046X DNA Decipher Journal 

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186 

  

Accelerating or Decelerating the Growth of Biological Subjects 

 

This is one of the most commonly documented effects of conscious intent on living organisms in 

both the Eastern and Western literature. The studies  reported under this category include the 

acceleration of seed germination and plant growth rate [79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89];  

a  directional increase/decrease in the growth rate of  in-vitro cancer cell cultures like human 

nasopharyngeal carcinoma cell line (CNE-2), human breast cancer cell lines, lung cancer cells 

(SPC-A1), liver cancer cell line (BEL-7402), erythroleukemia (K562), promyelocytic leukemia, 

CNE-2, SGC-7901 gastric adenocarcinoma, spleen cells of mice and  lung tumor cell line (LA-

795), etc. [90, 91, 92, 93, 94, 1]; bi-directional effects on the growth of bacterial cultures such as 

E-coli [95,96] and Salmonella typhimurium [97]; and inhibition of in-vivo tumor growth in mice 

[94, 98, 99]. 

 

The typical in-vitro study involved randomly dividing laboratory-prepared cancer cells or other 

cultures into groups with at least one group being treated with intention or external bio-energy 

(like external qi), plus one or two control groups.  Sometimes, one group was treated by a sham 

healer (person without training in bioenergy healing).  

 

In vivo-models most commonly used mice inoculated with cancerous cells, which were then 

randomly divided into various groups with one group being treated by external qi or other 

spiritual healing method for a set period of time. The control group could be either non-treatment 

or sham treatment.  Then tumor size and the survival time were measured as the outcomes. 

 

Related to this type of study are experiments in which human intent was applied to revitalize 

fully denatured seeds and accelerate sprouting, producing measurable plants within minutes. One 

particularly gifted subject, Ms. Chulin Sun, has worked with dozens of scientists world-wide and 

been involved in hundreds of successful replications of this phenomenon over the past 16 years. 

Some of these studies involve revitalization of fried peas or cooked peanuts [100, 101, 102] 

while others report a statistically significant acceleration in the sprouting of peas [103], wheat 

[104], corn, watermelon seed, bean, flower seed and peanuts [101, 105]. 

  

 

Transcription/Translation and Differential Gene Expression 

 

Chien et al. [106] looked at the bi-directional effects of external qi on FS-4 human fibroblasts 

and found that "facilitating" qi produced a 1.8% increase in cell growth rate in 24 hrs, 10-15% 

increase in DNA synthesis and 3-5% increase in cell protein synthesis in a 2 hr period. With 

"inhibiting" qi, cell growth decreased by 6% in 24 hours, while DNA and protein synthesis 

decreased respectively by 20-23%, 35-48%.  

 

Zhang et al. [107] studied the effect of emitted qi on the nucleic acids of chick red blood cells 

and found a two-fold increase in DNA and 12-fold increase in RNA content. 

 



DNA Decipher Journal | May 2012 | Vol. 2 | Issue 2 | pp. 177-205 
Sidorov, L., & Chen, K., Biophysical Mechanisms of Genetic Regulation: Is There a Link to Mind-Body Healing? 

 

 
ISSN: 2159-046X DNA Decipher Journal 

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Related results include the ability of emitted qi to increase NK cell and K cell activities [108] 

and to enhance the number of active osteoclasts and the quality and quantity of both fibrous and 

bony callus tissue in laboratory rabbits [109]. 

 

These studies suggest that conscious intent may act by increasing the rate of cell-specific 

transcription/translation responsible for specialized functions, as well as possibly stimulating cell 

differentiation and/or recruitment. 

 

 

Structural Changes Caused by Intent or Mental Power 

 

D. Y. Chu of Peking University tested more than 20 qigong healers in controlled studies to 

explore the effects of EQT on the conformation of bio-molecules [110].  In her study, a circular 

dichroism (CD) spectrum was used to monitor the conformation of various bio-molecules, such 

as poly-glutamic acid, poly-lysine, metallothionein, and some RNAs.  After more than a hundred 

trials were repeated with different healers and controls, she found that the CD spectra of bio-

molecular samples were changed significantly after exposure to EQT in comparison with both 

controls and the baseline.  In general, the changes of the CD characteristic elliptisity were over 1-

10 x 103 dgr×cm2×dmol-1, and the maximum was 93.9 x 104 dgr×cm2×dmol-1. The change of 

elliptisity could be positive or negative depending on the intent of the qigong healer.  These 

findings were successfully replicated when she visited the US in 2000 [111]. 

 

Rein and McCraty [112] reported a 250% change in DNA conformation, directly correlating with 

the intent of a healer from a distance. The directional winding/unwinding of DNA under specific 

intent has been repeatedly demonstrated by Rein and his team over a number of years and 

experimental set-ups, with some samples showing more denaturation than could be obtained via 

normal heating or mechanical means [113]. Similar changes in the conformation of DNA and 

RNA samples have been found under the effect of conscious intent (external qi) by Lu Zuyin 

[114] and Sun et al. [115] as indicated by changes in the samples' ultraviolet absorption curve.     

 

In addition, statistically significant effects on erythrocyte cell membranes were documented by 

Braud et al. [116, 117] and Sun et al. [118]. These include the ability of healers and/or ordinary 

persons to decrease the rate of RBC hemolysis; to increased fluidity of the erythrocytic 

membrane; and to suppress activity of Na+, K+ of RBC membrane. 

 

Changes in cell colony architecture were also documented by Chen X. et al [119] and by Chen 

[120,121], correlating with a change in the types of glycoproteins expressed on the cell 

membrane surface - so this effect may also be a result of alterations in the specific genes 

expressed under the effect of external qi. 

 

 

Intent-Induced Mutation 

 

Nash [122] randomly assigned 60 ordinary subjects (not known to be psychically gifted) into 

three groups: one group mentally promoted mutation of lac-negative strains of e-coli to lac-



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positive strains in three test tubes, one group mentally inhibited mutation in three test tubes, and 

the rest 20 subjects worked as control.  All tube conditions were carefully blinded to the lab 

technicians.  He found that the mutation ratio of lac-positive to total bacteria was greater in the 

promoted tubes than that in the inhibited tubes (p < .005); and less in the inhibited tubes than in 

the control (p < .02). 

 

There are many more studies in this area that we will not discuss in detail here. For example, Liu 

et al [123] applied EQT as mutagenesis for micromonospora echinospord, and found that EQ has 

the ability to kill micro-organisms and change strains properties.  Pei et al [124] reported that 

mutation of E-coli C311 occurred after exposure to EQT.  Shan et al [125] also used the intent of 

the qigong healer as mutagenesis to select various antibiotic-producing strains in the 

pharmaceutical production, and had some success.  Bai et al. [103] reported that the seeds 

mentally induced to germinate rapidly were apparently genetically altered with significant 

differences in DNA extraction and Polymerase chain reaction.  

  

 

Morphological Alterations and Cell Differentiation  

 

Electron microscopy studies of malignant tissue extracted from laboratory animals treated with 

external qi have repeatedly shown clear histological signs of apoptosis and/or reversal of cancer 

features, when compared to controls. For example, in their study of  the inhibitory effect of EQT 

on human hepatocarcinoma in mice, Chen et al [126] found morphological alterations including 

nuclear condensation, nuclear fragmentation, decreased ratio of nucleus and cytoplasm,  swollen 

mitochondria with poorly organized mitochondrial cristae (some vacuolated) and many apoptotic 

bodies in the extracellular space. Shao et al. [127] looked at qigong-treated mice with implanted 

S180 sarcoma  and reported  that the averaged diameters of cells and nuclei, the ratio of nucleus 

to cytoplasm and the number of tumor cells division phase and Ag-NOR counts in nuclei in the 

sarcoma of EQT treated mice were all much less than those in the controls (p < 0.001). They also 

found that in the EQT treated mice a great number of sarcoma cells showed atrophy, 

degeneration, and pyknosis or karyolysis, while some membrane structures such as mitochondria 

appeared to be injured.  Finally, Li et al. [128] studied the effects of emitted qi on G422 

neurogliomas implanted in mice, finding that mitotic rates were reduced and the differentiation 

of the glioma cells tended to be reversed and the activity of NK and K cells was increased 

significantly compared to the tumor control.   

 

These several hundred studies, conducted over the past 3 decades by a large number of university 

and independent laboratories in countries like the US, England, China, Japan, Russia, Germany 

and others, represent a pioneering body of work whose importance cannot be overstated. 

Although not all of them have been conducted under ideal methodological conditions of 

blindness and control, and the reporting style is far from consistent across the field (see [42] for 

an outstanding synopsis and analysis of experimental quality in these different categories), the 

overall evidence is much too compelling and significant to ignore. Replicating these studies 

under proper, uniform academic standards is of course a necessary first step. However, many of 

the results obtained by independent laboratories appear to reinforce each other, to a degree that 



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certain general observations about the effect of mental intent on biological targets can already be 

drawn. 

 

 

A. SPECIFICITY OF INTENT 

 

 The effect of intentionality appears to be directional and target specific. For example, 

Achterberg and Rider showed that training patients in cell-specific visualization of either T 

lymphocytes or neutrophils resulted in statistical increase in cell blood levels correlating with the 

type of imagery employed [43].  

 

Becker used hypnotized subjects to demonstrate that they could decrease or increase the DC 

potential of specific areas of the body depending on the suggestion given (a suggestion of 

numbness in the left  arm resulted in no response to a pinprick stimulus and a drop to zero in the 

DC potential, while the pinprick response/DC potential remained almost unchanged for the right 

arm; the change in voltage was "exactly the same as that seen in standard chemical nerve block" 

[45 - p 90-91]. 

 

Many of the studies described above also reflect such a directional effect (see, for example, 129, 

41, 113, 47). 

 

  

B.  ELECTROMAGNETIC WINDOWS OF HEALING AND INTENT 

 

Studies by Zimmerman and Beck show that healers' hand and brain frequencies measured during 

active "healing states" sweep a 0.3-30 Hz range, with most activity in the 7-8 Hz area. These 

frequencies, which show an uncanny consistency across a remarkable number of cultures and 

healing traditions, appear to closely overlap the electromagnetic specificity windows used in 

clinical and laboratory applications to enhance neural regeneration (2 Hz); bone growth (7 Hz); 

ligament healing (10 Hz) and capillary and fibroblast proliferation (15, 20 and 72 Hz) [48].     

 

Both local and distant mental interactions have been shown to produce unusual EM signatures. 

Magnetic signals up to 105nT were found by Wu et al. during Qi emission by qigong 

practitioners [49]. Unusually high static charges (up to 221 volts) from the bodies of healers and 

psi-gifted people were reported by Watkins, Hochenegg, Shallis and Green [42 p157].  

Nakamura measured an increase in biophoton emission intensity from the hands of practitioners 

in the qigong state [50].  Wallace found that human biophoton emissions could be increased by 

subjects at will and measured  up to 100 times stronger emissions from the hands of gifted 

subjects compared to controls [51]. High surges in the magnetic field surrounding healers, or 

significant effects on distant magnetic sensors, have been published by Ullman, Watkins, Puthoff 

and Targ, Zimmerman and  Ostrander and Schroeder,  Sergeyev,  (52; 42 p 168; 39].  

Photographic film exposure in association with healing or clairvoyance experiments has been 

demonstrated in independent studies by Watkins, Turner and Zhao Yong-Jie [42  p 157, 169].  

Radin reports that the background ionizing radiation could be decreased in accordance to task 

instructions (p<0.05), only to suddenly increase above control levels 20 seconds after the 



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treatment period [53]. In a series of experiments involving therapeutic touch practitioners and 

their subjects,  gamma radiation levels significantly decreased in 100% of the subjects and at 

every body site tested [54, 55]. 

 

Finally, we should also ask ourselves what such capabilities tell us about the healer's metabolic 

status.  We know, for example, that advanced practitioners of Qigong can enter a special state 

(Bigu) in which they can subsist for weeks, sometimes months, on only 2-300 calories per day, 

while carrying on with normal activities. [56, 57]  This "super-efficient state", as Prof. Roy has 

described it, has been shown to be metabolically different from that of normal fasting - which 

suggests that the body somehow switches over to a different way to process and conserve energy. 

Is there a link between Bigu and the energetic phenomena described above? 

  

  

C. DISTANT MENTAL INTERACTIONS WITH LIVING SYSTEMS (DMILS) 

 

DMILS include a wide range of variables, from physiological parameters like EEG and galvanic 

skin response [40, 58, 59, 60] to the denaturation of DNA in solution [42, 61] to affecting the 

morbidity and mortality rates of HIV/AIDS patients by remote prayer groups [62]. Typically in 

these experiments the sender is isolated from the experimental group by distances ranging from a 

few meters (an adjacent room) up to thousands of kilometers and the subjects are blind to the 

sending period, so that a comparison can be made with the "non-influence" windows.  

 

The statistical significance of these remote effects across dozens of independent studies is highly 

consistent despite the subjects' inability to consciously "guess" the sending window. Some 

studies have shown a lag time to onset of effect in the order of seconds [59,60], while in others, 

paradoxically, an anticipatory effect has been demonstrated [58] -  consistent with decades of 

parapsychological retro-pk evidence, but a clear challenge to our current concept of information 

flow and causality. 

 

Such evidence of space and time non-locality is probably the single greatest reason for which 

spiritual healing continues to encounter major resistance as a legitimate research subject from the 

scientific establishment. And yet at a physics theoretical level there is nothing that prohibits such 

effects from taking place: indeed, if there is one salient observation to be made on the basis of 

our foregoing discussion, it is that modern medicine seems to have almost entirely disassociated 

itself from the biophysical bases of life: current thinking appears to stop mysteriously at the 

biomolecular level, completely oblivious to the physics that lie beneath. Our challenge is to take 

this next step and place the current, biomolecular understanding of genetic regulation into a 

broader context - hoping that some of the answers which have eluded us so far, such as the onset 

criticality and reversal of malignant programs, will become more obvious at this level of the 

control hierarchy.  

 

  

 

 

 



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III. A NEW PERSPECTIVE ON THE GENETIC CODE 
 

 

A.   A HIERARCHY OF GENETIC REGULATORY MECHANISMS: 

 

Even a brief survey of the literature, such as we have undertaken, suggests that there are at least 

three main levels of control mechanisms dictating the unfolding of genetic programs: 

 

1. THE BIOCHEMICAL LEVEL: this includes, but is not limited to, the triplet genetic code and 

the newly discovered histone code; mechanisms such as the availability of cellular chemical 

messengers, molecular feedback loops and cis-/ trans-regulation work on this level, controlling to 

at least some degree the sequence of different genes' expression. 

 

2. THE BIOPHYSICAL LEVEL: this can further be divided into local and non-local effects. 

 

 2A.  LOCAL  control refers to the conformational effects of electromagnetic fields on 

chromatin, enzymes and cell membranes - which in turn affect the exposure of given genes and 

the rate of transcription/translation, plus possibly the rate of DNA synthesis and cell mitosis. 

 

 2B. NON-LOCAL effects include endogenous field coherence, electromagnetic 

interference grids, superconduction, photon localization phenomena and the possibility of non-

material, wave-based genetic hybridization and regeneration, as demonstrated by the experiments 

of Gariaev and Kangeng. 

 

3. THE CONSCIOUS LEVEL.  As we suggested before, it is difficult to tell at this point whether 

consciousness and mental intent act both locally and non-locally, although the existence of 

DMILS and anticipatory effects is a strong indication that we need to look beyond simple 

electromagnetic entrainment between healer and patient.  

 

Once we recognize that genetic programs are continuously modulated by all these different 

parameters, we need to ask ourselves a new set of questions. For example: 

 

1. What is the correct order of these elements in the hierarchy? 

 

2. How do level 1 and 2 mechanisms interface with conscious intent? (EM or other physical 

substrate?) 

 

3. How do coherent biophoton fields interact with environmental EMFs? 

 

4. How does conscious intent modulate endogenous EMFs? 

 

5. What is the power/frequency/polarization profile of biophoton emissions under different states 

of consciousness and how does it vary with various intentions or forms of visualization? 

 



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6. What is the basis of target specificity and bi-directional effects in controlled healing/pk 

studies? 

 

7. How is information transmitted non-locally? 

 

  

B. PRELIMINARY FRAMEWORK 

 

To begin addressing these questions, it is important to re-emphasize the biophysical perspective 

on living tissues emerging from the works cited above. According to this view, the coherence of 

endogenous EM fields and liquid crystal properties of biomolecules account for: 

 

 NONLOCAL COMMUNICATION THROUGHOUT THE ORGANISM/ 

TISSUE/POPULATION 

 

o -SYNCHRONIZED BEHAVIOR OF BILLIONS OF CELLS 

 

o EXQUISITE SENSITIVITY AND SPECIFICITY TO WEAK STIMULI 

 

o HIGHLY EFFICIENT ENERGY UTILIZATION 

 

 POSSIBLE BRAIN-BODY ELECTROMAGNETIC CONTINUUM AND TUNING 

REGULATORY MECHANISM FOR TISSUE-LEVEL INTERFERENCE EFFECTS 

 

    

C.  WORKING HYPOTHESES 

 

1. INTENT-DRIVEN CHROMATIN DECONDENSATION AS A FACTOR IN 

TRANSCRIPTION? 

 

It is generally accepted that the conformation of the chromatin fiber must change reversibly in 

processes that require the access of regulatory proteins and enzymes to the DNA template (such 

as in transcription, replication and repair). Van Holde and Zlatanova have suggested [63, 64] that 

one of the major conformational changes that occurs during DNA compaction is a collapse of the 

angle made between three consecutive nucleosomes (internucleosomal angle), probably mediated 

by electrostatic changes in histone interactions with linker DNA. 

 

Could such a change in angle be partly controlled by the electromagnetic hologram grid nodes 

postulated by Gariaev, Popp and others? If electrostatic interactions are responsible for 

chromatin folding/unfolding, it would be easy to see how changes in the frequency or 

polarization angle of DNA-associated biophotons could alter the locus of action of such pre-

transcriptional decondensation. The demonstrated ability of conscious intent to produce 

winding/unwinding of in-vitro chromatin and to directionally influence transcription becomes 

highly significant in this context.  One other supporting piece of evidence is the published 

experiments of Yan Xin [65] in which he repeatedly demonstrated the ability of external qi to 



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alter the polarization of targeted He-Ne laser beams from distances ranging between 7-2000 km. 

The change in polarization occurred within an hour of the external qi emission, as repeated sharp 

fluctuations averaging 6-7 degrees and 10-12% change in intensity of the normal beam, 

compared to baseline. No difference was recorded in the controls.  

 

  

 

2. MEDITATION AS PSYCHO-PHYSIOLOGICAL REMODELING 

 

 We propose that qigong and other meditative techniques work by progressively increasing the 

overall coherence ("qi flow"?) of the body's liquid crystal matrix via conscious mental driving, in 

a way not dissimilar to laser pumping or the gradual orientation of ferromagnetic particles in an 

EM field. Meditation frequencies could engage the thalamic silent periods (as Oschman has 

suggested) and possibly other frequency-window pacemakers, and thus drive the configurational 

states that the body naturally cycles through, to sensitize its LC matrix to particular frequencies. 

Moreover, the semiconductor nature of living tissues suggests that, with repeated passage of an 

EM current through them, their sensitivity to subsequent signals should increase - a property 

which, we believe, is critical to the understanding of long-term physiological changes seen in 

meditators [66, 67]. The maintenance of a mentally-driven, permanent tighter-than-average 

molecular coherence  would, in our model, lead  to a gradual increase in tissue liquid 

crystallinity, more efficient signal detection/transmission and hence greater perceptual 

sensitivity,  energy efficiency (Bigu) and ability to correct local EM "contextual errors". 

 

   

3. DO SPECIFIC INTENTS TRANSLATE INTO CHARACTERISTIC BRAIN-BODY WAVE 

FORMS? 

 

As we have seen earlier, Becker has shown that an organism's somatic DC field correlates in 

very specific ways with its state of consciousness:  using salamanders for test subjects, Becker 

found that under anesthesia, their peripheral voltages dropped to zero, and even reversed in very 

deep stages [4 p. 111].  Similar instances of reversal in body polarity are reported as occurring in 

human subjects monitored during deep trances induced in preparation for remote viewing.  In 

Spiritual Healing, Benor reports on a study by Rein and Laskow which found that  four different 

intentions by the same healer produced different body magnetic emissions which correlated with 

different biological effects on tumor cell cultures [42 p. 159].  

 

As we have seen earlier, the bi-directional effect of intent on living targets is also mirrored, 

remarkably, by the bi-phasic response of  tissues to specific EM frequency windows (section I-

B). 

 

Furthermore, it is highly interesting to note the close parallel between the genetic-level effects of 

healing intent as described in [1] and those of weak electromagnetic fields as discussed earlier in 

this paper (i.e. altered levels of mRNAs and proteins, increased enzyme activities, decrease in 

tumor growth and cell mitotic index, tumor cell alterations in shape and membrane discontinuity, 

increased apoptosis, accelerated differentiation - as well as seed revitalization and hybridization 



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with the Gariaev/Kangeng techniques). The fact that many of these bioelectromagnetic studies 

found no adverse EMF effects on normal cells also seems to parallel the regulatory influence of 

healing intent [42, 78]. 

 

Is there a link between effective mental healing intent, or the altered state of consciousness 

required to produce it, and these unusual EM emissions? Are characteristic frequencies/spectra 

required for particular healing effects?  And do these unusual EM signals play an active role in 

healing (perhaps by entrainment and frequency synchronization with the patient, as Oschman 

suggests) - or are they merely by-products of a deeper interpersonal communication mechanism 

we have yet to discover? 

 

Based on the evidence presented in this paper, we tend to agree with suggestions by Beck, 

Oschman and Becker that healers produce characteristic electromagnetic frequencies which can 

exert specific biological effects on their target. However, we would like to qualify this statement 

by adding the following observations: 

 

1. Frequency may not be the only parameter involved in modulating the EM signal. In view of 

Popp's and Gariaev's data, we have reason to believe that the phase and polarization of 

endogenous fields are also under the effect of conscious intent, which may be self-generated or 

transmitted non-locally by a healer. 

 

Thus the specificity of guided imagery may be the result of unique windows of frequency/ 

polarization   excited at the level of the cerebral cortex, then spreading globally along neural and 

perineural pathways. It is also possible that concentration on complex sensory modalities (i.e. the 

vividness of imagery) synchronizes larger areas of the cortex, resulting in a more powerful 

signal. Gariaev's contextual holographic paradigm further suggests that a pathologic EM 

environment may be less stable than that of healthy tissue, and thus more easily modified. 

Finally, we could also make an argument that stress, or other chronic emotional disturbances, 

represent a possible source of de-synchronization with partial loss of endogenous field 

coherence. 

 

2. Another point that cannot be overemphasized is that the presence of electromagnetic 

signatures associated with intent does not necessarily imply an EM transmission mechanism (i.e. 

via proximal frequency, entrainment or coupling to the Schumann resonance, as previously 

discussed by Oschman, Becker and Sidorov) - but simply that these ubiquitous EM signals may 

be produced as a secondary, local effect of the primary interaction. While EM coupling cannot 

be excluded in some situations, we need to realize that the nonlocal characteristics of mental 

healing (target specificity, distance and time independence) require more than a classical 

communication framework (see below). 

 

 

4.  DISTANT INFORMATION TRANSFER 

 

One of the most remarkable features of distant mental interactions with living and inert systems 

is that they affect only the target samples, leaving other (control) samples which are within the 



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same radius, statistically unchanged [49]. This strongly suggests that we are dealing with some 

form of entanglement between healer and target, rather than a classical, isotropic field-mediated 

process.  However, it has been repeatedly pointed out by Dossey, Walach, Pitkanen and others 

that in such cases the definition and exact mechanism of quantum entanglement would have to 

be expanded to account  for the insertion/extraction of intelligent information and for the 

notorious problem of decoherence in complex quantum systems. 

 

One comprehensive model that happens to contain such an extended concept of entanglement 

(together with numerous testable predictions which are supported by Gariaev's spectra and the 

presence of EM signatures at the target) is Pitkanen's Topological Geometrodynamics - an 8-

dimensional cosmology which is the product of 4-D Minkowskian space-time and the 

SU(3)/U(2) projective space of two complex dimensions [68, 69, 70, 71]. The geometrization of 

all basic interactions in TGD means that classical fields and matter form a pseudo-Feynman 

diagram in which the lines representing matter are replaced by spacetime sheets and virtual 

bosons are replaced by topological light rays ("massless extremals", MEs). MEs generate 

geometrical supracurrents which serve as a source of coherent photons and act as geometrical 

correlates of entanglement between distant material space/time sheets (the vertices of the pseudo-

Feynman diagram). One of the predictions of TGD is that focused mental intent produces 

topological field quanta - form-specific MEs which act as non-dissipative entanglement bridges 

between sender and target and which create characteristic ionic and electromagnetic signatures at 

both ends by their interaction with local magnetic flux tubes. 

 

Thus the solution proposed by Pitkanen appears to elegantly connect all the major observations 

we have discussed in our paper up to this point: a distant healer's conscious intent can be seen as 

generating form-specific geometrical currents which "propagate" non-dissipatively across 

arbitrarily large distances and which interact with the intended target by producing characteristic, 

coherent photon signatures. In turn these photons interact with the organism's endogenous 

electromagnetic field to modulate specific frequency or polarization parameters as described by 

Popp and Gariaev, thus altering interference patterns, regulating inter-cellular communication 

and the contextual environment of DNA/RNA expression inside cells. 

 

Of course, at this point it is difficult to fill in all the details, or indeed feel confident of the 

absolute validity of such a model. On the other hand, TGD opens experimental possibilities that 

have generally not been available with other theories of nonlocal healing. In [70] we have made 

a number of proposals regarding the types of tests that could be conducted as a preliminary 

verification of TGD predictions. Together with additional replications of the Gariaev 

experiments and of the major histo-molecular healing studies reviewed in this paper, we believe 

these ideas are well-worth pursuing as part of a future research program in complementary and 

alternative medicine. As opposed to previous mind-body research proposals, all these suggested 

protocols are remarkably concrete, objective, quantifiable and compatible with our need to 

construct a consistent physical theory. Since only innovative experimentation will be able to 

select the most promising theoretical models, and since in the absence of such models we cannot 

begin to incorporate this valuable body of evidence into our overall therapeutic strategy, we feel 

it is imperative that the NIH and other potential sponsors treat these proposals with the attention 

they deserve.  



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CONCLUSIONS 
 

Where do we go from here? The first step, of course, should be a well-coordinated experimental 

program replicating the major classes of mental interactions described in these two papers. 

Protocols could be set up to study the biophysical basis of differential response in normal and 

abnormal cell populations (target specificity/normalization); to compare the effect size, 

replicability, side effects and long-term response for biophysical and mind-body therapeutic 

approaches in specific pathological models; to study the ability of normal human populations to 

learn and effectively implement such mental techniques (clinical studies); and to investigate the 

interactions between external EM fields and endogenous currents with respect to genetic 

regulation. Finally, given the common challenge that nonlocal communication presents to 

researchers in physics, parapsychology and mind-body medicine, we strongly advocate the 

establishment of interdisciplinary teams to collaborate on innovative new protocols capable of 

extracting meaningful conclusions about this fundamental aspect of reality. 

 

From an applications point of view, we should start identifying the most effective meditation 

protocols for specific effects - i.e. enhancement of immune function, expression of specific 

genes, and suppression of pathogens or reversal of malignant cell behavior/induction of 

apoptosis. It is also important to start designing and standardizing teaching programs, perhaps 

through the use of biofeedback methods to evaluate the effectiveness of teachers' and students' 

meditation on specific biological parameters. Understanding the interactions between mind-body 

interventions and conventional treatment modalities (such as the demonstrated increase in drug 

uptake and reduction in chemotherapy side effects with concurrent qigong practice) is another 

long-term goal, which should allow us to eventually integrate such multi-modality therapies for 

optimal results with minimal iatrogenic trauma to the organism. 

 

Finally, we would like to take a step back and end this presentation with a philosophical 

observation. For more than a century, the common assumption in parapsychology research has 

been that the brain is the primary detection organ for subconscious/ anomalous cognition. 

However, in spite of this experimental focus, there is a remarkable lack of evidence supporting 

this contention - in fact we now know that certain peripheral responses to anomalous stimuli, 

such as the galvanic skin response, are highly consistent in the absence of any conscious 

awareness of these stimuli. Is the brain the only conceivable transducer of nonlocal information? 

 

Indeed, the literature shows that psi function manifests across the full taxonomic continuum, 

from humans to animals [41, 58, 73, 74, 77] to plants and individual cells [72, 42]. Since such 

consistent features are generally attributed to a very successful adaptive mechanism, and 

Pitkanen's TGD predicts a fractal hierarchy of biological emitters/receivers for nonlocal 

communication, could it be that the exquisite sensitivity of genetic material (DNA, RNA, 

protein) to mental intent may in fact reflect a deep evolutionary principle?  For these first forms 

of life, devoid of what we would call a sensory system, chemical and electromagnetic 

interactions with the environment would have been one, albeit purely random, type of 

"orientation" response. However, the complex behavior of organisms starting from the very 

bottom of the taxonomic tree (see virus and prion dynamics, DNA repair and transcription, etc) 

strongly suggest that behavioral adaptations were set in place, which clearly reflect a directional, 



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self-serving interaction with the environment and that we are at a loss to explain on purely 

biomolecular grounds. Could the survival instinct of primitive organisms qualify as 

consciousness - suggesting that the genetic material in our bodies might in fact be the oldest and 

primary "antenna" for nonlocal communication?  While this may at first look like a rhetorical 

question, the sobering realization that we are still in the dark about the higher-level programs 

regulating the spatial and temporal expression of DNA [2,3,77], together with the evidence 

presented in this paper, suggest a positive answer. And if conscious intent has the ability to shape 

our organism's response to environmental challenges by acting all the way down to DNA, RNA 

and protein levels, then it is indeed the most versatile and potent therapeutic intervention we 

could ever conceive. 

 

 

 

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