id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
dti-1338	Hatakeyama, Yuji; Hatakeyama, Junko; Takahashi, Atsushi; Oka, Kyoko; Tsuruga, Eichi; Inai, Tetsuichiro; Sawa, Yoshihiko	The Effect of Valproic Acid on Mesenchymal Pluripotent Cell Proliferation and Differentiation in Extracellular Matrices	2011	9	.pdf	application/pdf	5458	248	52	Previous studies have reported that VPA effects osteogenesis in vivo and in vitro, yet it remains unclear whether VPA promotes cell differentiation of osteoblasts derived from mesenchymal cells. Keywords: mesenchymal cells, valproic acid, cell proliferation http:/dx.doi.org/10.4137/DTI.S6534 http://www.la-press.com http://www.la-press.com http://www.la-press.com/drug-target-insights-journal-j23 http://www.la-press.com mailto:yuji_hatakey@hotmail.com hatakeyama et al 2 Drug Target Insights 2011:5 Introduction Valproic acid (2-n-propylpentanoic acid, VPA) is an effective and widely used antiepileptic and anticon- vulsant drug, and recent studies have reported that VPA influences osteogenesis in vivo and in vitro.1–4 It has been reported that VPA has no effect on osteo- genesis identified with calcification nodule forma- tion by a preosteoblast cell line derived from mouse calvaria, MC3T3-E1 cells.5	cache/dti-1338.pdf	txt/dti-1338.txt