id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
dti-1352	Gumuslu, Esen; Mutlu, Oguz; Sunnetci, Deniz; Ulak, Guner; Celikyurt, Ipek K.; Cine, Naci; Akar, Furuzan; Savlı, Hakan; Erden, Faruk	The Antidepressant Agomelatine Improves Memory Deterioration and Upregulates CREB and BDNF Gene Expression Levels in Unpredictable Chronic Mild Stress (UCMS)-Exposed Mice	2014	11	.pdf	application/pdf	8348	484	56	The results of our study revealed that chronic agomelatine increased BDNF expression in the hippocampus, and our findings are consistent with those of recent studies.57,60 These findings provide new information regarding the molecular mechanisms that contribute to the chronic effects of the new antidepressant agomelatine on brain function. Quantitative RT-PCR revealed that CREB and BDNF gene expression levels were downregulated in UCMS-exposed mice, and these alterations were reversed by chronic agomelatine or melatonin treatment.	cache/dti-1352.pdf	txt/dti-1352.txt