id	sid	eid	entity	type
dti-1416	1	1	4.0	CARDINAL
dti-1416	2	1	https://doi.org/10.1177/1177392819886875	DATE
dti-1416	2	2	13	CARDINAL
dti-1416	2	3	2019	CARDINAL
dti-1416	2	4	10.1177/1177392819886875	CARDINAL
dti-1416	3	1	pgx.	ORG
dti-1416	4	1	pgx	ORG
dti-1416	6	1	the us food and drug administration	ORG
dti-1416	6	2	fda	ORG
dti-1416	7	1	pgx references	ORG
dti-1416	9	1	1990	DATE
dti-1416	10	1	hgp	ORG
dti-1416	11	1	the united states	GPE
dti-1416	11	2	the united kingdom	GPE
dti-1416	11	3	france	GPE
dti-1416	11	4	germany	GPE
dti-1416	11	5	japan	GPE
dti-1416	11	6	china	GPE
dti-1416	13	1	2.91 billion	CARDINAL
dti-1416	13	2	years	DATE
dti-1416	13	3	april of 2003	DATE
dti-1416	15	1	hgp	ORG
dti-1416	17	1	pgx risk	ORG
dti-1416	18	1	pgx	ORG
dti-1416	20	1	one	CARDINAL
dti-1416	20	2	one or hundreds	CARDINAL
dti-1416	21	1	approximately 250 000 to 1 million	QUANTITY
dti-1416	22	1	kathleen b	PERSON
dti-1416	23	1	1school	CARDINAL
dti-1416	23	2	university of california	ORG
dti-1416	23	3	san francisco	GPE
dti-1416	23	4	san francisco	GPE
dti-1416	23	5	2center	CARDINAL
dti-1416	23	6	stanford university school of medicine	ORG
dti-1416	23	7	stanford	ORG
dti-1416	23	8	usa.	GPE
dti-1416	24	1	23	CARDINAL
dti-1416	25	1	pgx	ORG
dti-1416	26	1	pgx associations	ORG
dti-1416	28	1	pharmacogenomics	NORP
dti-1416	28	2	september 25, 2019	DATE
dti-1416	29	1	october 7, 2019	DATE
dti-1416	32	1	kathleen b orrico	ORG
dti-1416	32	2	university of california san francisco	ORG
dti-1416	32	3	1430	CARDINAL
dti-1416	32	4	menlo park	GPE
dti-1416	32	5	94025	DATE
dti-1416	32	6	886875	DATE
dti-1416	32	7	mailto:kathleen.orrico@ucsf.edu mailto:orricok@comcast.net 2	PRODUCT
dti-1416	37	1	1	CARDINAL
dti-1416	39	1	1	CARDINAL
dti-1416	40	1	5	CARDINAL
dti-1416	41	1	2	CARDINAL
dti-1416	41	2	4	CARDINAL
dti-1416	41	3	2	CARDINAL
dti-1416	42	1	0s	CARDINAL
dti-1416	42	2	1s	CARDINAL
dti-1416	42	3	4	CARDINAL
dti-1416	43	1	4	CARDINAL
dti-1416	43	2	1	CARDINAL
dti-1416	43	3	1	CARDINAL
dti-1416	44	1	2	CARDINAL
dti-1416	44	2	gc	ORG
dti-1416	44	3	3	CARDINAL
dti-1416	45	1	1	CARDINAL
dti-1416	48	1	1	CARDINAL
dti-1416	48	2	over 6 feet	QUANTITY
dti-1416	53	1	50 000 000 to 300 000 000	QUANTITY
dti-1416	53	2	hundreds to thousands	CARDINAL
dti-1416	53	3	1	CARDINAL
dti-1416	53	4	2100	CARDINAL
dti-1416	53	5	60	CARDINAL
dti-1416	54	1	2	CARDINAL
dti-1416	55	1	1	CARDINAL
dti-1416	56	1	2	CARDINAL
dti-1416	59	1	orrico 3	PERSON
dti-1416	59	2	2	CARDINAL
dti-1416	60	1	46	CARDINAL
dti-1416	60	2	23	CARDINAL
dti-1416	60	3	1	CARDINAL
dti-1416	60	4	1	CARDINAL
dti-1416	60	5	22	CARDINAL
dti-1416	60	6	1	CARDINAL
dti-1416	60	7	22	CARDINAL
dti-1416	66	1	3 proteins.7	TIME
dti-1416	70	1	a few hundred to over 2 million	CARDINAL
dti-1416	74	1	hugo	EVENT
dti-1416	77	1	66	CARDINAL
dti-1416	77	2	pgx	ORG
dti-1416	77	3	pharmgkb).10	GPE
dti-1416	78	1	2	CARDINAL
dti-1416	78	2	1	CARDINAL
dti-1416	79	1	1	CARDINAL
dti-1416	79	2	2	CARDINAL
dti-1416	81	1	2	CARDINAL
dti-1416	86	1	pgx	ORG
dti-1416	87	1	over 99.9%	PERCENT
dti-1416	88	1	less than 0.1%	PERCENT
dti-1416	90	1	asterisk	ORG
dti-1416	90	2	number 1	CARDINAL
dti-1416	90	3	1	CARDINAL
dti-1416	91	1	more than 1	CARDINAL
dti-1416	91	2	1	CARDINAL
dti-1416	94	1	snp	ORG
dti-1416	94	2	1	CARDINAL
dti-1416	96	1	snp	ORG
dti-1416	97	1	4	CARDINAL
dti-1416	97	2	cyp2c19	CARDINAL
dti-1416	97	3	2a	CARDINAL
dti-1416	97	4	2a	CARDINAL
dti-1416	97	5	681	CARDINAL
dti-1416	97	6	681g	CARDINAL
dti-1416	98	1	1	CARDINAL
dti-1416	98	2	2	CARDINAL
dti-1416	98	3	2a	CARDINAL
dti-1416	99	1	fda	ORG
dti-1416	99	2	pms	ORG
dti-1416	100	1	cnv	PERSON
dti-1416	100	2	greater than 2	CARDINAL
dti-1416	101	1	2	CARDINAL
dti-1416	103	1	cnv	ORG
dti-1416	103	2	less than 2	CARDINAL
dti-1416	104	1	one	CARDINAL
dti-1416	108	1	pgx	ORG
dti-1416	109	1	asterisk	ORG
dti-1416	111	1	fda	ORG
dti-1416	114	1	2	CARDINAL
dti-1416	116	1	approximately 25%	PERCENT
dti-1416	117	1	22	CARDINAL
dti-1416	118	1	4	CARDINAL
dti-1416	119	1	one	CARDINAL
dti-1416	120	1	one	CARDINAL
dti-1416	120	2	12.6%	PERCENT
dti-1416	120	3	30 000	CARDINAL
dti-1416	120	4	0	CARDINAL
dti-1416	120	5	1	CARDINAL
dti-1416	120	6	3	CARDINAL
dti-1416	120	7	5% to 10%	PERCENT
dti-1416	120	8	200	CARDINAL
dti-1416	121	1	1	CARDINAL
dti-1416	121	2	4	CARDINAL
dti-1416	123	1	1	CARDINAL
dti-1416	124	1	more than 2	CARDINAL
dti-1416	125	1	1	CARDINAL
dti-1416	125	2	2	CARDINAL
dti-1416	126	1	orrico 5	ORG
dti-1416	127	1	pms	ORG
dti-1416	127	2	2	CARDINAL
dti-1416	128	1	pms	ORG
dti-1416	130	1	1/*17	CARDINAL
dti-1416	130	2	at least 1	CARDINAL
dti-1416	131	1	2	CARDINAL
dti-1416	131	2	1	CARDINAL
dti-1416	131	3	1	CARDINAL
dti-1416	131	4	9/*41 or *	CARDINAL
dti-1416	133	1	first	ORDINAL
dti-1416	134	1	pgx resource	ORG
dti-1416	134	2	stanford university	ORG
dti-1416	135	1	pgx knowledge	ORG
dti-1416	136	1	the united states	GPE
dti-1416	136	2	canada	GPE
dti-1416	136	3	japan	GPE
dti-1416	136	4	netherlands	GPE
dti-1416	139	1	pgx clinical practice	ORG
dti-1416	139	2	first	ORDINAL
dti-1416	141	1	ums	PERSON
dti-1416	141	2	pms	ORG
dti-1416	142	1	ems	ORG
dti-1416	142	2	cpic	GPE
dti-1416	142	3	fda	ORG
dti-1416	142	4	less than 18 years old	DATE
dti-1416	143	1	the royal dutch association	ORG
dti-1416	144	1	ums	PERSON
dti-1416	144	2	pms	ORG
dti-1416	145	1	canadian	NORP
dti-1416	146	1	one	CARDINAL
dti-1416	146	2	pgx information	ORG
dti-1416	147	1	approximately 15%	PERCENT
dti-1416	148	1	hla gene	PERSON
dti-1416	148	2	6	CARDINAL
dti-1416	149	1	1	CARDINAL
dti-1416	150	1	3	CARDINAL
dti-1416	150	2	4	CARDINAL
dti-1416	150	3	5	CARDINAL
dti-1416	150	4	6	CARDINAL
dti-1416	150	5	7	CARDINAL
dti-1416	150	6	8	CARDINAL
dti-1416	150	7	11	CARDINAL
dti-1416	150	8	12	CARDINAL
dti-1416	150	9	13	CARDINAL
dti-1416	150	10	15	CARDINAL
dti-1416	150	11	18	CARDINAL
dti-1416	150	12	19	CARDINAL
dti-1416	150	13	20	CARDINAL
dti-1416	150	14	21	CARDINAL
dti-1416	150	15	31	CARDINAL
dti-1416	150	16	36	CARDINAL
dti-1416	150	17	38	CARDINAL
dti-1416	150	18	40	CARDINAL
dti-1416	150	19	42	CARDINAL
dti-1416	150	20	44	CARDINAL
dti-1416	150	21	47	CARDINAL
dti-1416	150	22	51	CARDINAL
dti-1416	150	23	56	CARDINAL
dti-1416	150	24	57	CARDINAL
dti-1416	150	25	60	CARDINAL
dti-1416	150	26	62	CARDINAL
dti-1416	150	27	68	CARDINAL
dti-1416	150	28	69	CARDINAL
dti-1416	150	29	92	CARDINAL
dti-1416	150	30	96	CARDINAL
dti-1416	150	31	99	CARDINAL
dti-1416	150	32	100	CARDINAL
dti-1416	150	33	101	CARDINAL
dti-1416	150	34	114	CARDINAL
dti-1416	150	35	9	CARDINAL
dti-1416	150	36	10	CARDINAL
dti-1416	150	37	14	CARDINAL
dti-1416	150	38	17	CARDINAL
dti-1416	150	39	29	CARDINAL
dti-1416	150	40	41	CARDINAL
dti-1416	150	41	49	CARDINAL
dti-1416	150	42	50	CARDINAL
dti-1416	150	43	54	CARDINAL
dti-1416	150	44	55	CARDINAL
dti-1416	150	45	59	CARDINAL
dti-1416	150	46	72	CARDINAL
dti-1416	150	47	84	CARDINAL
dti-1416	150	48	1	CARDINAL
dti-1416	150	49	2	CARDINAL
dti-1416	150	50	27	CARDINAL
dti-1416	150	51	33	CARDINAL
dti-1416	150	52	34	CARDINAL
dti-1416	150	53	35	CARDINAL
dti-1416	150	54	39	CARDINAL
dti-1416	150	55	45	CARDINAL
dti-1416	150	56	46	CARDINAL
dti-1416	150	57	48	CARDINAL
dti-1416	150	58	53	CARDINAL
dti-1416	150	59	1	CARDINAL
dti-1416	150	60	35	CARDINAL
dti-1416	150	61	2	CARDINAL
dti-1416	150	62	22	CARDINAL
dti-1416	150	63	23	CARDINAL
dti-1416	150	64	24	CARDINAL
dti-1416	150	65	25	CARDINAL
dti-1416	150	66	26	CARDINAL
dti-1416	150	67	28	CARDINAL
dti-1416	150	68	30	CARDINAL
dti-1416	150	69	37	CARDINAL
dti-1416	150	70	43	CARDINAL
dti-1416	150	71	52	CARDINAL
dti-1416	150	72	58	CARDINAL
dti-1416	150	73	61	CARDINAL
dti-1416	150	74	63	CARDINAL
dti-1416	150	75	64	CARDINAL
dti-1416	150	76	65	CARDINAL
dti-1416	150	77	70	CARDINAL
dti-1416	150	78	71	CARDINAL
dti-1416	150	79	73	CARDINAL
dti-1416	150	80	74	CARDINAL
dti-1416	150	81	75	CARDINAL
dti-1416	150	82	81	CARDINAL
dti-1416	150	83	82	CARDINAL
dti-1416	150	84	83	CARDINAL
dti-1416	150	85	85	CARDINAL
dti-1416	150	86	86	CARDINAL
dti-1416	150	87	87	CARDINAL
dti-1416	150	88	88	CARDINAL
dti-1416	150	89	89	CARDINAL
dti-1416	150	90	90	CARDINAL
dti-1416	150	91	91	CARDINAL
dti-1416	150	92	93	CARDINAL
dti-1416	150	93	94	CARDINAL
dti-1416	150	94	95	CARDINAL
dti-1416	151	1	97	CARDINAL
dti-1416	152	1	98	CARDINAL
dti-1416	153	1	102	CARDINAL
dti-1416	154	1	103	CARDINAL
dti-1416	154	2	104	CARDINAL
dti-1416	155	1	105	CARDINAL
dti-1416	155	2	106	CARDINAL
dti-1416	155	3	107	CARDINAL
dti-1416	155	4	108	CARDINAL
dti-1416	155	5	109	CARDINAL
dti-1416	155	6	110	CARDINAL
dti-1416	155	7	111	CARDINAL
dti-1416	155	8	112	CARDINAL
dti-1416	155	9	113	CARDINAL
dti-1416	155	10	6	CARDINAL
dti-1416	156	1	stevens-johnson	PERSON
dti-1416	156	2	ten	CARDINAL
dti-1416	156	3	failure.27 stevens-johnson	FAC
dti-1416	156	4	ten	CARDINAL
dti-1416	157	1	10%	PERCENT
dti-1416	157	2	50%	PERCENT
dti-1416	157	3	ten	CARDINAL
dti-1416	158	1	1	CARDINAL
dti-1416	159	1	fda	ORG
dti-1416	160	1	han chinese	NORP
dti-1416	160	2	thai	NORP
dti-1416	160	3	malaysian	NORP
dti-1416	160	4	indonesian	NORP
dti-1416	160	5	filipino	LANGUAGE
dti-1416	160	6	south indian	NORP
dti-1416	160	7	as much as 10	CARDINAL
dti-1416	160	8	caucasian	NORP
dti-1416	161	1	fda	ORG
dti-1416	161	2	testing.28	GPE
dti-1416	161	3	fda	ORG
dti-1416	161	4	mpe	ORG
dti-1416	162	1	hla-a and	PERSON
dti-1416	162	2	hla-a*1301	PERSON
dti-1416	162	3	fda	ORG
dti-1416	165	1	hgp	ORG
dti-1416	165	2	$500 million	MONEY
dti-1416	165	3	10 years	DATE
dti-1416	165	4	first	ORDINAL
dti-1416	165	5	2018	DATE
dti-1416	165	6	2 to 8 weeks	DATE
dti-1416	165	7	less than $1000	MONEY
dti-1416	166	1	a matter of days	DATE
dti-1416	166	2	a few hundred dollars	MONEY
dti-1416	167	1	1977	DATE
dti-1416	167	2	frederick sanger	PERSON
dti-1416	167	3	1	CARDINAL
dti-1416	167	4	millions	CARDINAL
dti-1416	168	1	one	CARDINAL
dti-1416	169	1	today	DATE
dti-1416	169	2	millions	CARDINAL
dti-1416	169	3	consumers.32	PERSON
dti-1416	173	1	pgx testing	ORG
dti-1416	173	2	1	CARDINAL
dti-1416	173	3	50	CARDINAL
dti-1416	175	1	pgx test	ORG
dti-1416	182	1	pgx subcommittees	ORG
dti-1416	184	1	pgx driven drug	ORG
dti-1416	185	1	orrico 7	PERSON
dti-1416	188	1	1	CARDINAL
dti-1416	190	1	bethesda	GPE
dti-1416	190	2	md	GPE
dti-1416	191	1	july 16, 2019	DATE
dti-1416	192	1	august 6, 2019	DATE
dti-1416	193	1	2	CARDINAL
dti-1416	194	1	washington	GPE
dti-1416	194	2	dc	GPE
dti-1416	196	1	january 9, 2019	DATE
dti-1416	197	1	september 1, 2019	DATE
dti-1416	198	1	3	CARDINAL
dti-1416	198	2	venter jc	PERSON
dti-1416	198	3	adams md	PERSON
dti-1416	198	4	myers	GPE
dti-1416	201	1	2001;291:1304-1351	CARDINAL
dti-1416	202	1	4	CARDINAL
dti-1416	203	1	vancouver	GPE
dti-1416	203	2	bc	ORG
dti-1416	203	3	canada	GPE
dti-1416	203	4	human proteome organization	ORG
dti-1416	204	1	2016	DATE
dti-1416	205	1	september 1, 2019	DATE
dti-1416	206	1	5	CARDINAL
dti-1416	206	2	genetics home	ORG
dti-1416	208	1	bethesda	GPE
dti-1416	208	2	md	GPE
dti-1416	210	1	august 20, 2019	DATE
dti-1416	211	1	september 2, 2019	DATE
dti-1416	212	1	6	CARDINAL
dti-1416	215	1	november 12, 2018	DATE
dti-1416	216	1	september 2, 2019	DATE
dti-1416	217	1	7	CARDINAL
dti-1416	219	1	bethesda	GPE
dti-1416	219	2	md	GPE
dti-1416	220	1	august 20, 2019	DATE
dti-1416	221	1	september 2, 2019	DATE
dti-1416	222	1	8	CARDINAL
dti-1416	223	1	ma	PERSON
dti-1416	224	1	curr opin	PERSON
dti-1416	224	2	clin nutr metab care	ORG
dti-1416	225	1	2011;14:28-34	DATE
dti-1416	227	1	9	CARDINAL
dti-1416	229	1	bethesda	PERSON
dti-1416	229	2	md	GPE
dti-1416	231	1	august 20, 2019	DATE
dti-1416	232	1	september 2, 2019.	DATE
dti-1416	233	1	10	CARDINAL
dti-1416	234	1	whirl-carrillo	PERSON
dti-1416	234	2	hebert jm	PERSON
dti-1416	234	3	pharmacogenomics	NORP
dti-1416	235	1	clin pharmacol	ORG
dti-1416	236	1	2012;92(4):414-417	CARDINAL
dti-1416	239	1	washington	GPE
dti-1416	239	2	dc	GPE
dti-1416	241	1	march 26, 2019	DATE
dti-1416	242	1	september 2, 2019.	DATE
dti-1416	243	1	12	CARDINAL
dti-1416	244	1	johnson ja	PERSON
dti-1416	244	2	cavallari lh	PERSON
dti-1416	244	3	pharmacogenetics	PERSON
dti-1416	245	1	pharmacol rev	PERSON
dti-1416	246	1	2013;65(3):987-1009	DATE
dti-1416	247	1	13	CARDINAL
dti-1416	248	1	food and drug administration	ORG
dti-1416	251	1	september 3, 2019	DATE
dti-1416	252	1	september 5, 2019	DATE
dti-1416	253	1	14	DATE
dti-1416	254	1	hoskins jm	PERSON
dti-1416	254	2	mcleod hl	PERSON
dti-1416	256	1	2011;17:244-251	CARDINAL
dti-1416	257	1	doi:10.1016	GPE
dti-1416	257	2	15	CARDINAL
dti-1416	258	1	miller na	PERSON
dti-1416	258	2	whirl-carrillo m	PERSON
dti-1416	258	3	klein te	PERSON
dti-1416	260	1	clin pharmacol	ORG
dti-1416	261	1	2018;103(3):399	CARDINAL
dti-1416	262	1	16	CARDINAL
dti-1416	266	1	june 21, 2019	DATE
dti-1416	267	1	july 3, 2019	DATE
dti-1416	268	1	17	CARDINAL
dti-1416	269	1	zhou sf	PERSON
dti-1416	269	2	i. clin	PERSON
dti-1416	270	1	2009;48:689-723	CARDINAL
dti-1416	271	1	18	CARDINAL
dti-1416	272	1	dean l. codeine	PERSON
dti-1416	274	1	march 16, 2017	DATE
dti-1416	275	1	september 4, 2019.	DATE
dti-1416	276	1	19	CARDINAL
dti-1416	276	2	beoris m	PERSON
dti-1416	276	3	amos wilson j	PERSON
dti-1416	276	4	garces ja	PERSON
dti-1416	276	5	lukowiak aa	PERSON
dti-1416	277	1	us	GPE
dti-1416	279	1	2016;26(2):96-99	CARDINAL
dti-1416	280	1	20	CARDINAL
dti-1416	282	1	fda	ORG
dti-1416	283	1	med lett	PRODUCT
dti-1416	284	1	2017;59(1521):86-88	CARDINAL
dti-1416	285	1	21	CARDINAL
dti-1416	290	1	august 28, 2019	DATE
dti-1416	291	1	september 4, 2019	DATE
dti-1416	292	1	22	CARDINAL
dti-1416	296	1	september 4, 2019	DATE
dti-1416	297	1	23	CARDINAL
dti-1416	300	1	https://www.pharmgkb.org/guidelines	ORG
dti-1416	300	2	september 4, 2019	DATE
dti-1416	301	1	24	CARDINAL
dti-1416	301	2	lee a.	PERSON
dti-1416	303	1	london	GPE
dti-1416	303	2	england	GPE
dti-1416	303	3	2006:7	CARDINAL
dti-1416	304	1	25	CARDINAL
dti-1416	304	2	negrini s	PERSON
dti-1416	304	3	l. hla-associated	PERSON
dti-1416	306	1	2017;18:1441-1457	CARDINAL
dti-1416	308	1	26	CARDINAL
dti-1416	311	1	https://cpicpgx.org/guidelines/.	ORG
dti-1416	311	2	july 11, 2019	DATE
dti-1416	312	1	september 5, 2019	DATE
dti-1416	313	1	27	CARDINAL
dti-1416	313	2	negrini s	PERSON
dti-1416	313	3	becquemont l. pharmacogenetics	PERSON
dti-1416	314	1	therapie	PERSON
dti-1416	315	1	2017;72:231-243	CARDINAL
dti-1416	316	1	28	CARDINAL
dti-1416	320	1	september 3, 2019	DATE
dti-1416	321	1	september 5, 2019.	DATE
dti-1416	322	1	29	CARDINAL
dti-1416	323	1	pharmacogenomics	NORP
dti-1416	324	1	hla-a	PERSON
dti-1416	324	2	hla-b.	PERSON
dti-1416	326	1	march 20, 2019	DATE
dti-1416	327	1	september 4, 2019	DATE
dti-1416	328	1	30	CARDINAL
dti-1416	329	1	national human genome research institute	ORG
dti-1416	332	1	july 10, 2019	DATE
dti-1416	333	1	september 5, 2019.	DATE
dti-1416	335	1	reuter ja	PERSON
dti-1416	335	2	spacek	PERSON
dti-1416	335	3	snyder mp	PERSON
dti-1416	337	1	2015;58:586-597	CARDINAL
dti-1416	338	1	32	CARDINAL
dti-1416	341	1	bethesda	GPE
dti-1416	341	2	md	GPE
dti-1416	343	1	september 3, 2019	DATE
dti-1416	344	1	september 4, 2019	DATE
dti-1416	345	1	https://www.genome.gov/human-genome-project	NORP
dti-1416	346	1	https://www.fda.gov/drugs/science-research-drugs/table-pharmacogenomic-biomarkers-drug-labeling https://www.fda.gov/drugs/science-research-drugs/table-pharmacogenomic-biomarkers-drug-labeling	TIME