id	sid	tid	token	lemma	pos
dti-1297	1	1	untitled	untitled	ADJ
dti-1297	1	2	drug	drug	NOUN
dti-1297	1	3	target	target	NOUN
dti-1297	1	4	insights	insight	NOUN
dti-1297	1	5	2006	2006	NUM
dti-1297	1	6	:	:	PUNCT
dti-1297	1	7	1	1	NUM
dti-1297	1	8	1–4	1–4	NUM
dti-1297	1	9	1	1	NUM
dti-1297	1	10	review	review	NOUN
dti-1297	1	11	correspondence	correspondence	NOUN
dti-1297	1	12	:	:	PUNCT
dti-1297	1	13	11	11	NUM
dti-1297	1	14	jalan	jalan	PROPN
dti-1297	1	15	tan	tan	PROPN
dti-1297	1	16	tock	tock	PROPN
dti-1297	1	17	seng	seng	PROPN
dti-1297	1	18	,	,	PUNCT
dti-1297	1	19	singapore	singapore	PROPN
dti-1297	1	20	308433	308433	NUM
dti-1297	1	21	.	.	PUNCT
dti-1297	2	1	tel	tel	ADP
dti-1297	2	2	:	:	PUNCT
dti-1297	2	3	(	(	PUNCT
dti-1297	2	4	65	65	NUM
dti-1297	2	5	)	)	PUNCT
dti-1297	2	6	6357	6357	NUM
dti-1297	2	7	-	-	SYM
dti-1297	2	8	7533	7533	NUM
dti-1297	2	9	;	;	PUNCT
dti-1297	2	10	fax	fax	NOUN
dti-1297	2	11	:	:	PUNCT
dti-1297	2	12	(	(	PUNCT
dti-1297	2	13	65	65	NUM
dti-1297	2	14	)	)	PUNCT
dti-1297	2	15	6256	6256	NUM
dti-1297	2	16	-	-	SYM
dti-1297	2	17	9178	9178	NUM
dti-1297	2	18	;	;	PUNCT
dti-1297	2	19	email	email	NOUN
dti-1297	2	20	:	:	PUNCT
dti-1297	2	21	obgpjt@nus.edu.sg	obgpjt@nus.edu.sg	ADV
dti-1297	2	22	please	please	INTJ
dti-1297	2	23	note	note	VERB
dti-1297	2	24	that	that	SCONJ
dti-1297	2	25	this	this	DET
dti-1297	2	26	article	article	NOUN
dti-1297	2	27	may	may	AUX
dti-1297	2	28	not	not	PART
dti-1297	2	29	be	be	AUX
dti-1297	2	30	used	use	VERB
dti-1297	2	31	for	for	ADP
dti-1297	2	32	commercial	commercial	ADJ
dti-1297	2	33	purposes	purpose	NOUN
dti-1297	2	34	.	.	PUNCT
dti-1297	3	1	for	for	ADP
dti-1297	3	2	further	further	ADJ
dti-1297	3	3	information	information	NOUN
dti-1297	3	4	please	please	INTJ
dti-1297	3	5	refer	refer	VERB
dti-1297	3	6	to	to	ADP
dti-1297	3	7	the	the	DET
dti-1297	3	8	copyright	copyright	NOUN
dti-1297	3	9	statement	statement	NOUN
dti-1297	3	10	at	at	ADP
dti-1297	3	11	http://www.la-press.com/copyright.htm	http://www.la-press.com/copyright.htm	PROPN
dti-1297	3	12	neurogenesis	neurogenesis	NOUN
dti-1297	3	13	and	and	CCONJ
dti-1297	3	14	alzheimer	alzheimer	PROPN
dti-1297	3	15	’s	’s	PART
dti-1297	3	16	disease	disease	NOUN
dti-1297	3	17	philippe	philippe	PROPN
dti-1297	3	18	taupin1,2,3	taupin1,2,3	PROPN
dti-1297	3	19	1national	1national	NUM
dti-1297	3	20	neuroscience	neuroscience	NOUN
dti-1297	3	21	institute	institute	NOUN
dti-1297	3	22	,	,	PUNCT
dti-1297	3	23	singapore	singapore	PROPN
dti-1297	3	24	.	.	PUNCT
dti-1297	4	1	2national	2national	NUM
dti-1297	4	2	university	university	PROPN
dti-1297	4	3	of	of	ADP
dti-1297	4	4	singapore	singapore	PROPN
dti-1297	4	5	.	.	PUNCT
dti-1297	5	1	3nanyang	3nanyang	NUM
dti-1297	5	2	technological	technological	ADJ
dti-1297	5	3	university	university	NOUN
dti-1297	5	4	,	,	PUNCT
dti-1297	5	5	singapore	singapore	PROPN
dti-1297	5	6	.	.	PUNCT
dti-1297	6	1	abstract	abstract	ADJ
dti-1297	6	2	:	:	PUNCT
dti-1297	6	3	alzheimer	alzheimer	PROPN
dti-1297	6	4	’s	’s	PART
dti-1297	6	5	disease	disease	NOUN
dti-1297	6	6	(	(	PUNCT
dti-1297	6	7	ad	ad	NOUN
dti-1297	6	8	)	)	PUNCT
dti-1297	6	9	is	be	AUX
dti-1297	6	10	a	a	DET
dti-1297	6	11	neurodegenerative	neurodegenerative	ADJ
dti-1297	6	12	disease	disease	NOUN
dti-1297	6	13	,	,	PUNCT
dti-1297	6	14	characterized	characterize	VERB
dti-1297	6	15	in	in	ADP
dti-1297	6	16	the	the	DET
dti-1297	6	17	brain	brain	NOUN
dti-1297	6	18	by	by	ADP
dti-1297	6	19	amyloid	amyloid	NOUN
dti-1297	6	20	plaque	plaque	NOUN
dti-1297	6	21	deposits	deposit	NOUN
dti-1297	6	22	and	and	CCONJ
dti-1297	6	23	neurofi	neurofi	ADV
dti-1297	6	24	brillary	brillary	ADJ
dti-1297	6	25	tangles	tangle	NOUN
dti-1297	6	26	.	.	PUNCT
dti-1297	7	1	it	it	PRON
dti-1297	7	2	is	be	AUX
dti-1297	7	3	the	the	DET
dti-1297	7	4	most	most	ADV
dti-1297	7	5	common	common	ADJ
dti-1297	7	6	form	form	NOUN
dti-1297	7	7	of	of	ADP
dti-1297	7	8	dementia	dementia	NOUN
dti-1297	7	9	among	among	ADP
dti-1297	7	10	older	old	ADJ
dti-1297	7	11	people	people	NOUN
dti-1297	7	12	.	.	PUNCT
dti-1297	8	1	there	there	PRON
dti-1297	8	2	is	be	VERB
dti-1297	8	3	at	at	ADP
dti-1297	8	4	present	present	ADJ
dti-1297	8	5	no	no	DET
dti-1297	8	6	cure	cure	NOUN
dti-1297	8	7	for	for	ADP
dti-1297	8	8	ad	ad	NOUN
dti-1297	8	9	,	,	PUNCT
dti-1297	8	10	and	and	CCONJ
dti-1297	8	11	current	current	ADJ
dti-1297	8	12	treatments	treatment	NOUN
dti-1297	8	13	consist	consist	VERB
dti-1297	8	14	mainly	mainly	ADV
dti-1297	8	15	in	in	ADP
dti-1297	8	16	drug	drug	NOUN
dti-1297	8	17	therapy	therapy	NOUN
dti-1297	8	18	.	.	PUNCT
dti-1297	9	1	potential	potential	ADJ
dti-1297	9	2	therapies	therapy	NOUN
dti-1297	9	3	for	for	ADP
dti-1297	9	4	ad	ad	NOUN
dti-1297	9	5	involve	involve	VERB
dti-1297	9	6	gene	gene	NOUN
dti-1297	9	7	and	and	CCONJ
dti-1297	9	8	cellular	cellular	ADJ
dti-1297	9	9	therapy	therapy	NOUN
dti-1297	9	10	.	.	PUNCT
dti-1297	10	1	the	the	DET
dti-1297	10	2	recent	recent	ADJ
dti-1297	10	3	confi	confi	ADJ
dti-1297	10	4	rmation	rmation	NOUN
dti-1297	10	5	that	that	SCONJ
dti-1297	10	6	neurogenesis	neurogenesis	NOUN
dti-1297	10	7	occurs	occur	VERB
dti-1297	10	8	in	in	ADP
dti-1297	10	9	the	the	DET
dti-1297	10	10	adult	adult	NOUN
dti-1297	10	11	brain	brain	NOUN
dti-1297	10	12	and	and	CCONJ
dti-1297	10	13	neural	neural	ADJ
dti-1297	10	14	stem	stem	NOUN
dti-1297	10	15	cells	cell	NOUN
dti-1297	10	16	(	(	PUNCT
dti-1297	10	17	nscs	nscs	PROPN
dti-1297	10	18	)	)	PUNCT
dti-1297	10	19	reside	reside	VERB
dti-1297	10	20	in	in	ADP
dti-1297	10	21	the	the	DET
dti-1297	10	22	adult	adult	NOUN
dti-1297	10	23	central	central	ADJ
dti-1297	10	24	nervous	nervous	ADJ
dti-1297	10	25	system	system	NOUN
dti-1297	10	26	(	(	PUNCT
dti-1297	10	27	cns	cns	NOUN
dti-1297	10	28	)	)	PUNCT
dti-1297	10	29	provide	provide	VERB
dti-1297	10	30	new	new	ADJ
dti-1297	10	31	opportunities	opportunity	NOUN
dti-1297	10	32	for	for	ADP
dti-1297	10	33	cellular	cellular	ADJ
dti-1297	10	34	therapy	therapy	NOUN
dti-1297	10	35	in	in	ADP
dti-1297	10	36	the	the	DET
dti-1297	10	37	cns	cns	NOUN
dti-1297	10	38	,	,	PUNCT
dti-1297	10	39	particularly	particularly	ADV
dti-1297	10	40	for	for	ADP
dti-1297	10	41	ad	ad	NOUN
dti-1297	10	42	,	,	PUNCT
dti-1297	10	43	and	and	CCONJ
dti-1297	10	44	to	to	PART
dti-1297	10	45	better	well	ADV
dti-1297	10	46	understand	understand	VERB
dti-1297	10	47	brain	brain	NOUN
dti-1297	10	48	physiopathology	physiopathology	NOUN
dti-1297	10	49	.	.	PUNCT
dti-1297	11	1	hence	hence	ADV
dti-1297	11	2	,	,	PUNCT
dti-1297	11	3	researchers	researcher	NOUN
dti-1297	11	4	have	have	AUX
dti-1297	11	5	aimed	aim	VERB
dti-1297	11	6	at	at	ADP
dti-1297	11	7	characterizing	characterize	VERB
dti-1297	11	8	neurogenesis	neurogenesis	NOUN
dti-1297	11	9	in	in	ADP
dti-1297	11	10	patients	patient	NOUN
dti-1297	11	11	with	with	ADP
dti-1297	11	12	ad	ad	NOUN
dti-1297	11	13	.	.	PUNCT
dti-1297	12	1	studies	study	NOUN
dti-1297	12	2	show	show	VERB
dti-1297	12	3	that	that	SCONJ
dti-1297	12	4	neurogenesis	neurogenesis	NOUN
dti-1297	12	5	is	be	AUX
dti-1297	12	6	increased	increase	VERB
dti-1297	12	7	in	in	ADP
dti-1297	12	8	these	these	DET
dti-1297	12	9	patients	patient	NOUN
dti-1297	12	10	,	,	PUNCT
dti-1297	12	11	and	and	CCONJ
dti-1297	12	12	in	in	ADP
dti-1297	12	13	animal	animal	NOUN
dti-1297	12	14	models	model	NOUN
dti-1297	12	15	of	of	ADP
dti-1297	12	16	ad	ad	NOUN
dti-1297	12	17	.	.	PUNCT
dti-1297	13	1	the	the	DET
dti-1297	13	2	effect	effect	NOUN
dti-1297	13	3	of	of	ADP
dti-1297	13	4	drugs	drug	NOUN
dti-1297	13	5	used	use	VERB
dti-1297	13	6	to	to	PART
dti-1297	13	7	treat	treat	VERB
dti-1297	13	8	ad	ad	NOUN
dti-1297	13	9	on	on	ADP
dti-1297	13	10	neurogenesis	neurogenesis	NOUN
dti-1297	13	11	is	be	AUX
dti-1297	13	12	currently	currently	ADV
dti-1297	13	13	being	be	AUX
dti-1297	13	14	investigated	investigate	VERB
dti-1297	13	15	,	,	PUNCT
dti-1297	13	16	to	to	PART
dti-1297	13	17	identify	identify	VERB
dti-1297	13	18	whether	whether	SCONJ
dti-1297	13	19	neurogenesis	neurogenesis	NOUN
dti-1297	13	20	contributes	contribute	VERB
dti-1297	13	21	to	to	ADP
dti-1297	13	22	their	their	PRON
dti-1297	13	23	therapeutic	therapeutic	ADJ
dti-1297	13	24	activities	activity	NOUN
dti-1297	13	25	.	.	PUNCT
dti-1297	14	1	keywords	keyword	NOUN
dti-1297	14	2	:	:	PUNCT
dti-1297	14	3	neural	neural	ADJ
dti-1297	14	4	stem	stem	NOUN
dti-1297	14	5	cells	cell	NOUN
dti-1297	14	6	,	,	PUNCT
dti-1297	14	7	hippocampus	hippocampus	NOUN
dti-1297	14	8	,	,	PUNCT
dti-1297	14	9	learning	learning	NOUN
dti-1297	14	10	and	and	CCONJ
dti-1297	14	11	memory	memory	NOUN
dti-1297	14	12	,	,	PUNCT
dti-1297	14	13	acetylcholinesterase	acetylcholinesterase	NOUN
dti-1297	14	14	inhibitors	inhibitor	NOUN
dti-1297	14	15	,	,	PUNCT
dti-1297	14	16	n	n	CCONJ
dti-1297	14	17	-	-	PUNCT
dti-1297	14	18	methyl	methyl	NOUN
dti-1297	14	19	-	-	PUNCT
dti-1297	14	20	d	d	NOUN
dti-1297	14	21	-	-	PUNCT
dti-1297	14	22	aspartateglutamate	aspartateglutamate	NOUN
dti-1297	14	23	receptor	receptor	NOUN
dti-1297	14	24	antagonist	antagonist	NOUN
dti-1297	14	25	,	,	PUNCT
dti-1297	14	26	cellular	cellular	ADJ
dti-1297	14	27	therapy	therapy	NOUN
dti-1297	14	28	.	.	PUNCT
dti-1297	15	1	introduction	introduction	NOUN
dti-1297	15	2	the	the	DET
dti-1297	15	3	recent	recent	ADJ
dti-1297	15	4	confi	confi	ADJ
dti-1297	15	5	rmation	rmation	NOUN
dti-1297	15	6	that	that	SCONJ
dti-1297	15	7	neurogenesis	neurogenesis	NOUN
dti-1297	15	8	occurs	occur	VERB
dti-1297	15	9	in	in	ADP
dti-1297	15	10	the	the	DET
dti-1297	15	11	adult	adult	NOUN
dti-1297	15	12	brain	brain	NOUN
dti-1297	15	13	and	and	CCONJ
dti-1297	15	14	nscs	nscs	PROPN
dti-1297	15	15	reside	reside	VERB
dti-1297	15	16	in	in	ADP
dti-1297	15	17	the	the	DET
dti-1297	15	18	adult	adult	NOUN
dti-1297	15	19	cns	cns	NOUN
dti-1297	15	20	in	in	ADP
dti-1297	15	21	various	various	ADJ
dti-1297	15	22	species	specie	NOUN
dti-1297	15	23	including	include	VERB
dti-1297	15	24	humans	human	NOUN
dti-1297	15	25	,	,	PUNCT
dti-1297	15	26	is	be	AUX
dti-1297	15	27	as	as	ADV
dti-1297	15	28	important	important	ADJ
dti-1297	15	29	for	for	ADP
dti-1297	15	30	cellular	cellular	ADJ
dti-1297	15	31	therapy	therapy	NOUN
dti-1297	15	32	in	in	ADP
dti-1297	15	33	the	the	DET
dti-1297	15	34	cns	cns	NOUN
dti-1297	15	35	,	,	PUNCT
dti-1297	15	36	particularly	particularly	ADV
dti-1297	15	37	for	for	ADP
dti-1297	15	38	neurodegenerative	neurodegenerative	ADJ
dti-1297	15	39	diseases	disease	NOUN
dti-1297	15	40	like	like	ADP
dti-1297	15	41	ad	ad	NOUN
dti-1297	15	42	,	,	PUNCT
dti-1297	15	43	as	as	ADP
dti-1297	15	44	for	for	ADP
dti-1297	15	45	our	our	PRON
dti-1297	15	46	understanding	understanding	NOUN
dti-1297	15	47	of	of	ADP
dti-1297	15	48	developmental	developmental	ADJ
dti-1297	15	49	biology	biology	NOUN
dti-1297	15	50	(	(	PUNCT
dti-1297	15	51	gage	gage	NOUN
dti-1297	15	52	,	,	PUNCT
dti-1297	15	53	2000	2000	NUM
dti-1297	15	54	;	;	PUNCT
dti-1297	15	55	taupin	taupin	NOUN
dti-1297	15	56	and	and	CCONJ
dti-1297	15	57	gage	gage	NOUN
dti-1297	15	58	,	,	PUNCT
dti-1297	15	59	2002	2002	NUM
dti-1297	15	60	)	)	PUNCT
dti-1297	15	61	.	.	PUNCT
dti-1297	16	1	environmental	environmental	ADJ
dti-1297	16	2	enrichment	enrichment	NOUN
dti-1297	16	3	,	,	PUNCT
dti-1297	16	4	drugs	drug	NOUN
dti-1297	16	5	,	,	PUNCT
dti-1297	16	6	trophic	trophic	ADJ
dti-1297	16	7	factors	factor	NOUN
dti-1297	16	8	,	,	PUNCT
dti-1297	16	9	neurotransmitters	neurotransmitter	NOUN
dti-1297	16	10	,	,	PUNCT
dti-1297	16	11	and	and	CCONJ
dti-1297	16	12	a	a	DET
dti-1297	16	13	broad	broad	ADJ
dti-1297	16	14	range	range	NOUN
dti-1297	16	15	of	of	ADP
dti-1297	16	16	physiopathological	physiopathological	ADJ
dti-1297	16	17	conditions	condition	NOUN
dti-1297	16	18	,	,	PUNCT
dti-1297	16	19	including	include	VERB
dti-1297	16	20	ad	ad	NOUN
dti-1297	16	21	,	,	PUNCT
dti-1297	16	22	modulate	modulate	VERB
dti-1297	16	23	adult	adult	NOUN
dti-1297	16	24	neurogenesis	neurogenesis	NOUN
dti-1297	16	25	(	(	PUNCT
dti-1297	16	26	taupin	taupin	NOUN
dti-1297	16	27	,	,	PUNCT
dti-1297	16	28	2005	2005	NUM
dti-1297	16	29	)	)	PUNCT
dti-1297	16	30	.	.	PUNCT
dti-1297	17	1	recently	recently	ADV
dti-1297	17	2	,	,	PUNCT
dti-1297	17	3	using	use	VERB
dti-1297	17	4	a	a	DET
dti-1297	17	5	combination	combination	NOUN
dti-1297	17	6	of	of	ADP
dti-1297	17	7	mouse	mouse	NOUN
dti-1297	17	8	models	model	NOUN
dti-1297	17	9	and	and	CCONJ
dti-1297	17	10	x	x	NOUN
dti-1297	17	11	-	-	NOUN
dti-1297	17	12	irradiation	irradiation	NOUN
dti-1297	17	13	,	,	PUNCT
dti-1297	17	14	to	to	PART
dti-1297	17	15	inhibit	inhibit	VERB
dti-1297	17	16	neurogenesis	neurogenesis	NOUN
dti-1297	17	17	,	,	PUNCT
dti-1297	17	18	it	it	PRON
dti-1297	17	19	was	be	AUX
dti-1297	17	20	reported	report	VERB
dti-1297	17	21	that	that	SCONJ
dti-1297	17	22	antidepressants	antidepressant	NOUN
dti-1297	17	23	,	,	PUNCT
dti-1297	17	24	like	like	ADP
dti-1297	17	25	fl	fl	PRON
dti-1297	17	26	uoxetine	uoxetine	ADJ
dti-1297	17	27	,	,	PUNCT
dti-1297	17	28	increase	increase	VERB
dti-1297	17	29	hippocampal	hippocampal	ADJ
dti-1297	17	30	neurogenesis	neurogenesis	NOUN
dti-1297	17	31	,	,	PUNCT
dti-1297	17	32	which	which	PRON
dti-1297	17	33	contribute	contribute	VERB
dti-1297	17	34	to	to	ADP
dti-1297	17	35	their	their	PRON
dti-1297	17	36	behavioral	behavioral	ADJ
dti-1297	17	37	effects	effect	NOUN
dti-1297	17	38	(	(	PUNCT
dti-1297	17	39	santarelli	santarelli	PROPN
dti-1297	17	40	et	et	PROPN
dti-1297	17	41	al	al	PROPN
dti-1297	17	42	.	.	PROPN
dti-1297	17	43	2003	2003	NUM
dti-1297	17	44	)	)	PUNCT
dti-1297	17	45	.	.	PUNCT
dti-1297	18	1	researchers	researcher	NOUN
dti-1297	18	2	have	have	AUX
dti-1297	18	3	aimed	aim	VERB
dti-1297	18	4	to	to	PART
dti-1297	18	5	investigate	investigate	VERB
dti-1297	18	6	whether	whether	SCONJ
dti-1297	18	7	neurogenesis	neurogenesis	NOUN
dti-1297	18	8	may	may	AUX
dti-1297	18	9	contribute	contribute	VERB
dti-1297	18	10	to	to	ADP
dti-1297	18	11	the	the	DET
dti-1297	18	12	therapeutic	therapeutic	ADJ
dti-1297	18	13	effects	effect	NOUN
dti-1297	18	14	of	of	ADP
dti-1297	18	15	drugs	drug	NOUN
dti-1297	18	16	used	use	VERB
dti-1297	18	17	to	to	PART
dti-1297	18	18	treat	treat	VERB
dti-1297	18	19	other	other	ADJ
dti-1297	18	20	neurological	neurological	ADJ
dti-1297	18	21	diseases	disease	NOUN
dti-1297	18	22	and	and	CCONJ
dti-1297	18	23	disorders	disorder	NOUN
dti-1297	18	24	,	,	PUNCT
dti-1297	18	25	particularly	particularly	ADV
dti-1297	18	26	ad	ad	NOUN
dti-1297	18	27	(	(	PUNCT
dti-1297	18	28	jin	jin	NOUN
dti-1297	18	29	et	et	PROPN
dti-1297	18	30	al	al	PROPN
dti-1297	18	31	.	.	PROPN
dti-1297	18	32	2006	2006	NUM
dti-1297	18	33	)	)	PUNCT
dti-1297	18	34	.	.	PUNCT
dti-1297	19	1	alzheimer	alzheimer	PROPN
dti-1297	19	2	’s	’s	PART
dti-1297	19	3	disease	disease	NOUN
dti-1297	19	4	is	be	AUX
dti-1297	19	5	associated	associate	VERB
dti-1297	19	6	with	with	ADP
dti-1297	19	7	the	the	DET
dti-1297	19	8	loss	loss	NOUN
dti-1297	19	9	of	of	ADP
dti-1297	19	10	nerve	nerve	NOUN
dti-1297	19	11	cells	cell	NOUN
dti-1297	19	12	in	in	ADP
dti-1297	19	13	areas	area	NOUN
dti-1297	19	14	of	of	ADP
dti-1297	19	15	the	the	DET
dti-1297	19	16	brain	brain	NOUN
dti-1297	19	17	that	that	PRON
dti-1297	19	18	are	be	AUX
dti-1297	19	19	vital	vital	ADJ
dti-1297	19	20	to	to	ADP
dti-1297	19	21	memory	memory	NOUN
dti-1297	19	22	and	and	CCONJ
dti-1297	19	23	other	other	ADJ
dti-1297	19	24	mental	mental	ADJ
dti-1297	19	25	abilities	ability	NOUN
dti-1297	19	26	,	,	PUNCT
dti-1297	19	27	like	like	ADP
dti-1297	19	28	the	the	DET
dti-1297	19	29	hippocampus	hippocampus	NOUN
dti-1297	19	30	(	(	PUNCT
dti-1297	19	31	hardy	hardy	ADJ
dti-1297	19	32	and	and	CCONJ
dti-1297	19	33	selkoe	selkoe	ADJ
dti-1297	19	34	,	,	PUNCT
dti-1297	19	35	2002	2002	NUM
dti-1297	19	36	;	;	PUNCT
dti-1297	19	37	st	st	PROPN
dti-1297	19	38	george	george	PROPN
dti-1297	19	39	-	-	PUNCT
dti-1297	19	40	hyslop	hyslop	PROPN
dti-1297	19	41	and	and	CCONJ
dti-1297	19	42	petit	petit	NOUN
dti-1297	19	43	,	,	PUNCT
dti-1297	19	44	2005	2005	NUM
dti-1297	19	45	)	)	PUNCT
dti-1297	19	46	.	.	PUNCT
dti-1297	20	1	hence	hence	ADV
dti-1297	20	2	,	,	PUNCT
dti-1297	20	3	cognitive	cognitive	ADJ
dti-1297	20	4	impairments	impairment	NOUN
dti-1297	20	5	that	that	PRON
dti-1297	20	6	worsen	worsen	VERB
dti-1297	20	7	overtime	overtime	NOUN
dti-1297	20	8	are	be	AUX
dti-1297	20	9	major	major	ADJ
dti-1297	20	10	disabilities	disability	NOUN
dti-1297	20	11	of	of	ADP
dti-1297	20	12	ad	ad	NOUN
dti-1297	20	13	.	.	PUNCT
dti-1297	21	1	two	two	NUM
dti-1297	21	2	classes	class	NOUN
dti-1297	21	3	of	of	ADP
dti-1297	21	4	drugs	drug	NOUN
dti-1297	21	5	are	be	AUX
dti-1297	21	6	currently	currently	ADV
dti-1297	21	7	used	use	VERB
dti-1297	21	8	to	to	PART
dti-1297	21	9	treat	treat	VERB
dti-1297	21	10	patients	patient	NOUN
dti-1297	21	11	with	with	ADP
dti-1297	21	12	ad	ad	NOUN
dti-1297	21	13	:	:	PUNCT
dti-1297	21	14	acetylcholinesterase	acetylcholinesterase	NOUN
dti-1297	21	15	(	(	PUNCT
dti-1297	21	16	ache	ache	ADV
dti-1297	21	17	)	)	PUNCT
dti-1297	21	18	inhibitors	inhibitor	NOUN
dti-1297	21	19	,	,	PUNCT
dti-1297	21	20	like	like	ADP
dti-1297	21	21	tacrine	tacrine	NOUN
dti-1297	21	22	,	,	PUNCT
dti-1297	21	23	donepezil	donepezil	NOUN
dti-1297	21	24	,	,	PUNCT
dti-1297	21	25	galantamine	galantamine	NOUN
dti-1297	21	26	and	and	CCONJ
dti-1297	21	27	rivastigmine	rivastigmine	NOUN
dti-1297	21	28	,	,	PUNCT
dti-1297	21	29	and	and	CCONJ
dti-1297	21	30	an	an	DET
dti-1297	21	31	n	n	CCONJ
dti-1297	21	32	-	-	PUNCT
dti-1297	21	33	methyl	methyl	NOUN
dti-1297	21	34	-	-	PUNCT
dti-1297	21	35	d	d	NOUN
dti-1297	21	36	-	-	NOUN
dti-1297	21	37	aspartate	aspartate	NOUN
dti-1297	21	38	(	(	PUNCT
dti-1297	21	39	nmda)-glutamate	nmda)-glutamate	NOUN
dti-1297	21	40	receptor	receptor	NOUN
dti-1297	21	41	antagonist	antagonist	NOUN
dti-1297	21	42	,	,	PUNCT
dti-1297	21	43	like	like	ADP
dti-1297	21	44	memantine	memantine	NOUN
dti-1297	21	45	(	(	PUNCT
dti-1297	21	46	arrieta	arrieta	PROPN
dti-1297	21	47	et	et	PROPN
dti-1297	21	48	al	al	PROPN
dti-1297	21	49	.	.	PROPN
dti-1297	21	50	1998	1998	NUM
dti-1297	21	51	;	;	PUNCT
dti-1297	21	52	scarpini	scarpini	VERB
dti-1297	21	53	et	et	PROPN
dti-1297	21	54	al	al	PROPN
dti-1297	21	55	.	.	PROPN
dti-1297	21	56	2003	2003	NUM
dti-1297	21	57	;	;	PUNCT
dti-1297	21	58	wilkinson	wilkinson	PROPN
dti-1297	21	59	et	et	PROPN
dti-1297	21	60	al	al	PROPN
dti-1297	21	61	.	.	PROPN
dti-1297	21	62	2004	2004	NUM
dti-1297	21	63	;	;	PUNCT
dti-1297	21	64	mcshane	mcshane	PROPN
dti-1297	21	65	et	et	PROPN
dti-1297	21	66	al	al	PROPN
dti-1297	21	67	.	.	PROPN
dti-1297	21	68	2006	2006	NUM
dti-1297	21	69	)	)	PUNCT
dti-1297	21	70	.	.	PUNCT
dti-1297	22	1	these	these	DET
dti-1297	22	2	drugs	drug	NOUN
dti-1297	22	3	produce	produce	VERB
dti-1297	22	4	improvements	improvement	NOUN
dti-1297	22	5	in	in	ADP
dti-1297	22	6	cognitive	cognitive	ADJ
dti-1297	22	7	and	and	CCONJ
dti-1297	22	8	behavioral	behavioral	ADJ
dti-1297	22	9	symptoms	symptom	NOUN
dti-1297	22	10	,	,	PUNCT
dti-1297	22	11	but	but	CCONJ
dti-1297	22	12	their	their	PRON
dti-1297	22	13	role	role	NOUN
dti-1297	22	14	in	in	ADP
dti-1297	22	15	the	the	DET
dti-1297	22	16	pathogenesis	pathogenesis	NOUN
dti-1297	22	17	of	of	ADP
dti-1297	22	18	ad	ad	NOUN
dti-1297	22	19	is	be	AUX
dti-1297	22	20	unknown	unknown	ADJ
dti-1297	22	21	.	.	PUNCT
dti-1297	23	1	ache	ache	PROPN
dti-1297	23	2	inhibitors	inhibitor	NOUN
dti-1297	23	3	are	be	AUX
dti-1297	23	4	thought	think	VERB
dti-1297	23	5	to	to	PART
dti-1297	23	6	improve	improve	VERB
dti-1297	23	7	cognitive	cognitive	ADJ
dti-1297	23	8	functions	function	NOUN
dti-1297	23	9	by	by	ADP
dti-1297	23	10	enhancing	enhance	VERB
dti-1297	23	11	cholinergic	cholinergic	ADJ
dti-1297	23	12	neurotransmission	neurotransmission	NOUN
dti-1297	23	13	in	in	ADP
dti-1297	23	14	affected	affect	VERB
dti-1297	23	15	brain	brain	NOUN
dti-1297	23	16	regions	region	NOUN
dti-1297	23	17	of	of	ADP
dti-1297	23	18	ad	ad	NOUN
dti-1297	23	19	.	.	PUNCT
dti-1297	24	1	neurogenesis	neurogenesis	NOUN
dti-1297	24	2	in	in	ADP
dti-1297	24	3	alzheimer	alzheimer	PROPN
dti-1297	24	4	’s	’s	PART
dti-1297	24	5	disease	disease	NOUN
dti-1297	24	6	jin	jin	PROPN
dti-1297	24	7	et	et	PROPN
dti-1297	24	8	al	al	PROPN
dti-1297	24	9	.	.	PROPN
dti-1297	25	1	(	(	PUNCT
dti-1297	25	2	2004	2004	NUM
dti-1297	25	3	)	)	PUNCT
dti-1297	25	4	studied	study	VERB
dti-1297	25	5	neurogenesis	neurogenesis	NOUN
dti-1297	25	6	from	from	ADP
dti-1297	25	7	autopsies	autopsy	NOUN
dti-1297	25	8	of	of	ADP
dti-1297	25	9	ad	ad	NOUN
dti-1297	25	10	brain	brain	NOUN
dti-1297	25	11	patients	patient	NOUN
dti-1297	25	12	.	.	PUNCT
dti-1297	26	1	the	the	DET
dti-1297	26	2	expression	expression	NOUN
dti-1297	26	3	of	of	ADP
dti-1297	26	4	markers	marker	NOUN
dti-1297	26	5	for	for	ADP
dti-1297	26	6	immature	immature	ADJ
dti-1297	26	7	neuronal	neuronal	ADJ
dti-1297	26	8	cells	cell	NOUN
dti-1297	26	9	,	,	PUNCT
dti-1297	26	10	doublecortin	doublecortin	PROPN
dti-1297	26	11	,	,	PUNCT
dti-1297	26	12	polysialylated	polysialylate	VERB
dti-1297	26	13	nerve	nerve	NOUN
dti-1297	26	14	cell	cell	NOUN
dti-1297	26	15	adhesion	adhesion	NOUN
dti-1297	26	16	molecule	molecule	NOUN
dti-1297	26	17	and	and	CCONJ
dti-1297	26	18	neurogenic	neurogenic	ADJ
dti-1297	26	19	differentiation	differentiation	NOUN
dti-1297	26	20	factor	factor	NOUN
dti-1297	26	21	,	,	PUNCT
dti-1297	26	22	increase	increase	NOUN
dti-1297	26	23	in	in	ADP
dti-1297	26	24	the	the	DET
dti-1297	26	25	subgranular	subgranular	ADJ
dti-1297	26	26	zone	zone	NOUN
dti-1297	26	27	(	(	PUNCT
dti-1297	26	28	sgz	sgz	PROPN
dti-1297	26	29	)	)	PUNCT
dti-1297	26	30	,	,	PUNCT
dti-1297	26	31	granular	granular	ADJ
dti-1297	26	32	layer	layer	NOUN
dti-1297	26	33	of	of	ADP
dti-1297	26	34	the	the	DET
dti-1297	26	35	dentate	dentate	ADJ
dti-1297	26	36	gyrus	gyrus	NOUN
dti-1297	26	37	(	(	PUNCT
dti-1297	26	38	dg	dg	NOUN
dti-1297	26	39	)	)	PUNCT
dti-1297	26	40	,	,	PUNCT
dti-1297	26	41	and	and	CCONJ
dti-1297	26	42	ca1	ca1	PROPN
dti-1297	26	43	region	region	NOUN
dti-1297	26	44	of	of	ADP
dti-1297	26	45	hippocampal	hippocampal	PROPN
dti-1297	26	46	ammon	ammon	PROPN
dti-1297	26	47	’s	’s	PART
dti-1297	26	48	horn	horn	NOUN
dti-1297	26	49	(	(	PUNCT
dti-1297	26	50	jin	jin	NOUN
dti-1297	26	51	et	et	PROPN
dti-1297	26	52	al	al	PROPN
dti-1297	26	53	.	.	PROPN
dti-1297	26	54	2004a	2004a	NUM
dti-1297	26	55	)	)	PUNCT
dti-1297	26	56	.	.	PUNCT
dti-1297	27	1	the	the	DET
dti-1297	27	2	sgz	sgz	PROPN
dti-1297	27	3	is	be	AUX
dti-1297	27	4	a	a	DET
dti-1297	27	5	layer	layer	NOUN
dti-1297	27	6	beneath	beneath	ADP
dti-1297	27	7	the	the	DET
dti-1297	27	8	granular	granular	ADJ
dti-1297	27	9	layer	layer	NOUN
dti-1297	27	10	.	.	PUNCT
dti-1297	28	1	newly	newly	ADV
dti-1297	28	2	generated	generate	VERB
dti-1297	28	3	neuronal	neuronal	ADJ
dti-1297	28	4	cells	cell	NOUN
dti-1297	28	5	in	in	ADP
dti-1297	28	6	the	the	DET
dti-1297	28	7	sgz	sgz	PROPN
dti-1297	28	8	migrate	migrate	NOUN
dti-1297	28	9	to	to	ADP
dti-1297	28	10	the	the	DET
dti-1297	28	11	granular	granular	ADJ
dti-1297	28	12	layer	layer	NOUN
dti-1297	28	13	where	where	SCONJ
dti-1297	28	14	they	they	PRON
dti-1297	28	15	differentiate	differentiate	VERB
dti-1297	28	16	into	into	ADP
dti-1297	28	17	neuronal	neuronal	ADJ
dti-1297	28	18	cells	cell	NOUN
dti-1297	28	19	of	of	ADP
dti-1297	28	20	the	the	DET
dti-1297	28	21	dg	dg	NOUN
dti-1297	28	22	(	(	PUNCT
dti-1297	28	23	taupin	taupin	NOUN
dti-1297	28	24	and	and	CCONJ
dti-1297	28	25	gage	gage	NOUN
dti-1297	28	26	,	,	PUNCT
dti-1297	28	27	2002	2002	NUM
dti-1297	28	28	)	)	PUNCT
dti-1297	28	29	.	.	PUNCT
dti-1297	29	1	studies	study	NOUN
dti-1297	29	2	also	also	ADV
dti-1297	29	3	show	show	VERB
dti-1297	29	4	that	that	SCONJ
dti-1297	29	5	neurogenesis	neurogenesis	NOUN
dti-1297	29	6	is	be	AUX
dti-1297	29	7	modulated	modulate	VERB
dti-1297	29	8	in	in	ADP
dti-1297	29	9	animal	animal	NOUN
dti-1297	29	10	models	model	NOUN
dti-1297	29	11	of	of	ADP
dti-1297	29	12	ad	ad	NOUN
dti-1297	29	13	.	.	PUNCT
dti-1297	30	1	animal	animal	NOUN
dti-1297	30	2	models	model	NOUN
dti-1297	30	3	have	have	AUX
dti-1297	30	4	been	be	AUX
dti-1297	30	5	devised	devise	VERB
dti-1297	30	6	to	to	PART
dti-1297	30	7	study	study	VERB
dti-1297	30	8	genes	gene	NOUN
dti-1297	30	9	involved	involve	VERB
dti-1297	30	10	in	in	ADP
dti-1297	30	11	ad	ad	NOUN
dti-1297	30	12	,	,	PUNCT
dti-1297	30	13	like	like	ADP
dti-1297	30	14	presenilin	presenilin	PROPN
dti-1297	30	15	1	1	NUM
dti-1297	30	16	(	(	PUNCT
dti-1297	30	17	psen1	psen1	ADJ
dti-1297	30	18	)	)	PUNCT
dti-1297	30	19	and	and	CCONJ
dti-1297	30	20	amyloid	amyloid	NOUN
dti-1297	30	21	-	-	PUNCT
dti-1297	30	22	beta	beta	NOUN
dti-1297	30	23	protein	protein	NOUN
dti-1297	30	24	precursor	precursor	NOUN
dti-1297	30	25	(	(	PUNCT
dti-1297	30	26	app	app	PROPN
dti-1297	30	27	)	)	PUNCT
dti-1297	30	28	(	(	PUNCT
dti-1297	30	29	german	german	NOUN
dti-1297	30	30	and	and	CCONJ
dti-1297	30	31	eisch	eisch	ADJ
dti-1297	30	32	,	,	PUNCT
dti-1297	30	33	2004	2004	NUM
dti-1297	30	34	)	)	PUNCT
dti-1297	30	35	.	.	PUNCT
dti-1297	31	1	drug	drug	NOUN
dti-1297	31	2	target	target	NOUN
dti-1297	31	3	insights	insight	NOUN
dti-1297	31	4	2006	2006	NUM
dti-1297	31	5	:	:	PUNCT
dti-1297	31	6	12	12	NUM
dti-1297	31	7	philippe	philippe	PROPN
dti-1297	31	8	taupin	taupin	PROPN
dti-1297	31	9	psen1	psen1	PROPN
dti-1297	31	10	and	and	CCONJ
dti-1297	31	11	app	app	NOUN
dti-1297	31	12	are	be	AUX
dti-1297	31	13	associated	associate	VERB
dti-1297	31	14	with	with	ADP
dti-1297	31	15	most	most	ADJ
dti-1297	31	16	cases	case	NOUN
dti-1297	31	17	of	of	ADP
dti-1297	31	18	early	early	ADJ
dti-1297	31	19	-	-	PUNCT
dti-1297	31	20	onset	onset	NOUN
dti-1297	31	21	ad	ad	NOUN
dti-1297	31	22	,	,	PUNCT
dti-1297	31	23	a	a	DET
dti-1297	31	24	rare	rare	ADJ
dti-1297	31	25	hereditary	hereditary	ADJ
dti-1297	31	26	form	form	NOUN
dti-1297	31	27	of	of	ADP
dti-1297	31	28	dementia	dementia	NOUN
dti-1297	31	29	(	(	PUNCT
dti-1297	31	30	st	st	PROPN
dti-1297	31	31	george	george	PROPN
dti-1297	31	32	-	-	PUNCT
dti-1297	31	33	hyslop	hyslop	PROPN
dti-1297	31	34	and	and	CCONJ
dti-1297	31	35	petit	petit	NOUN
dti-1297	31	36	,	,	PUNCT
dti-1297	31	37	2005	2005	NUM
dti-1297	31	38	)	)	PUNCT
dti-1297	31	39	.	.	PUNCT
dti-1297	32	1	neurogenesis	neurogenesis	NOUN
dti-1297	32	2	is	be	AUX
dti-1297	32	3	positively	positively	ADV
dti-1297	32	4	regulated	regulate	VERB
dti-1297	32	5	in	in	ADP
dti-1297	32	6	the	the	DET
dti-1297	32	7	dg	dg	NOUN
dti-1297	32	8	of	of	ADP
dti-1297	32	9	transgenic	transgenic	NOUN
dti-1297	32	10	mice	mouse	NOUN
dti-1297	32	11	that	that	PRON
dti-1297	32	12	express	express	VERB
dti-1297	32	13	the	the	DET
dti-1297	32	14	swedish	swedish	ADJ
dti-1297	32	15	and	and	CCONJ
dti-1297	32	16	indiana	indiana	PROPN
dti-1297	32	17	app	app	PROPN
dti-1297	32	18	mutations	mutation	NOUN
dti-1297	32	19	,	,	PUNCT
dti-1297	32	20	a	a	DET
dti-1297	32	21	mutant	mutant	ADJ
dti-1297	32	22	form	form	NOUN
dti-1297	32	23	of	of	ADP
dti-1297	32	24	human	human	ADJ
dti-1297	32	25	app	app	NOUN
dti-1297	32	26	(	(	PUNCT
dti-1297	32	27	jin	jin	PROPN
dti-1297	32	28	et	et	PROPN
dti-1297	32	29	al	al	PROPN
dti-1297	32	30	.	.	PROPN
dti-1297	32	31	2004b	2004b	NUM
dti-1297	32	32	)	)	PUNCT
dti-1297	32	33	,	,	PUNCT
dti-1297	32	34	and	and	CCONJ
dti-1297	32	35	negatively	negatively	ADV
dti-1297	32	36	regulated	regulate	VERB
dti-1297	32	37	in	in	ADP
dti-1297	32	38	the	the	DET
dti-1297	32	39	dg	dg	NOUN
dti-1297	32	40	and	and	CCONJ
dti-1297	32	41	subventricular	subventricular	PROPN
dti-1297	32	42	zone	zone	NOUN
dti-1297	32	43	(	(	PUNCT
dti-1297	32	44	svz	svz	PROPN
dti-1297	32	45	)	)	PUNCT
dti-1297	32	46	of	of	ADP
dti-1297	32	47	knock	knock	NOUN
dti-1297	32	48	-	-	PUNCT
dti-1297	32	49	out	out	ADP
dti-1297	32	50	mice	mouse	NOUN
dti-1297	32	51	for	for	ADP
dti-1297	32	52	psen1	psen1	NOUN
dti-1297	32	53	and	and	CCONJ
dti-1297	32	54	app	app	PROPN
dti-1297	32	55	(	(	PUNCT
dti-1297	32	56	feng	feng	PROPN
dti-1297	32	57	et	et	PROPN
dti-1297	32	58	al	al	PROPN
dti-1297	32	59	.	.	PROPN
dti-1297	32	60	2001	2001	NUM
dti-1297	32	61	;	;	PUNCT
dti-1297	32	62	wen	wen	PROPN
dti-1297	32	63	et	et	PROPN
dti-1297	32	64	al	al	PROPN
dti-1297	32	65	.	.	PROPN
dti-1297	32	66	2002	2002	NUM
dti-1297	32	67	)	)	PUNCT
dti-1297	32	68	.	.	PUNCT
dti-1297	33	1	the	the	DET
dti-1297	33	2	dg	dg	PROPN
dti-1297	33	3	and	and	CCONJ
dti-1297	33	4	svz	svz	PROPN
dti-1297	33	5	are	be	AUX
dti-1297	33	6	the	the	DET
dti-1297	33	7	two	two	NUM
dti-1297	33	8	main	main	ADJ
dti-1297	33	9	regions	region	NOUN
dti-1297	33	10	of	of	ADP
dti-1297	33	11	the	the	DET
dti-1297	33	12	cns	cns	NOUN
dti-1297	33	13	where	where	SCONJ
dti-1297	33	14	neurogenesis	neurogenesis	NOUN
dti-1297	33	15	occurs	occur	VERB
dti-1297	33	16	in	in	ADP
dti-1297	33	17	the	the	DET
dti-1297	33	18	adult	adult	NOUN
dti-1297	33	19	(	(	PUNCT
dti-1297	33	20	taupin	taupin	NOUN
dti-1297	33	21	and	and	CCONJ
dti-1297	33	22	gage	gage	NOUN
dti-1297	33	23	,	,	PUNCT
dti-1297	33	24	2002	2002	NUM
dti-1297	33	25	)	)	PUNCT
dti-1297	33	26	.	.	PUNCT
dti-1297	34	1	these	these	DET
dti-1297	34	2	animal	animal	NOUN
dti-1297	34	3	studies	study	NOUN
dti-1297	34	4	were	be	AUX
dti-1297	34	5	performed	perform	VERB
dti-1297	34	6	using	use	VERB
dti-1297	34	7	bromodeoxyurine	bromodeoxyurine	NOUN
dti-1297	34	8	(	(	PUNCT
dti-1297	34	9	brdu	brdu	NOUN
dti-1297	34	10	)	)	PUNCT
dti-1297	34	11	labeling	labeling	NOUN
dti-1297	34	12	,	,	PUNCT
dti-1297	34	13	a	a	DET
dti-1297	34	14	thymidine	thymidine	ADJ
dti-1297	34	15	analog	analog	NOUN
dti-1297	34	16	that	that	PRON
dti-1297	34	17	incorporates	incorporate	VERB
dti-1297	34	18	into	into	ADP
dti-1297	34	19	the	the	DET
dti-1297	34	20	dna	dna	NOUN
dti-1297	34	21	of	of	ADP
dti-1297	34	22	dividing	divide	VERB
dti-1297	34	23	cells	cell	NOUN
dti-1297	34	24	during	during	ADP
dti-1297	34	25	the	the	DET
dti-1297	34	26	s	s	NOUN
dti-1297	34	27	-	-	NOUN
dti-1297	34	28	phase	phase	NOUN
dti-1297	34	29	of	of	ADP
dti-1297	34	30	the	the	DET
dti-1297	34	31	cell	cell	NOUN
dti-1297	34	32	cycle	cycle	NOUN
dti-1297	34	33	,	,	PUNCT
dti-1297	34	34	and	and	CCONJ
dti-1297	34	35	is	be	AUX
dti-1297	34	36	used	use	VERB
dti-1297	34	37	for	for	ADP
dti-1297	34	38	birthdating	birthdate	VERB
dti-1297	34	39	cells	cell	NOUN
dti-1297	34	40	and	and	CCONJ
dti-1297	34	41	monitoring	monitor	VERB
dti-1297	34	42	cell	cell	NOUN
dti-1297	34	43	proliferation	proliferation	NOUN
dti-1297	34	44	(	(	PUNCT
dti-1297	34	45	miller	miller	NOUN
dti-1297	34	46	and	and	CCONJ
dti-1297	34	47	nowakowski	nowakowski	ADJ
dti-1297	34	48	,	,	PUNCT
dti-1297	34	49	1988	1988	NUM
dti-1297	34	50	;	;	PUNCT
dti-1297	34	51	taupin	taupin	NOUN
dti-1297	34	52	and	and	CCONJ
dti-1297	34	53	gage	gage	NOUN
dti-1297	34	54	,	,	PUNCT
dti-1297	34	55	2002	2002	NUM
dti-1297	34	56	)	)	PUNCT
dti-1297	34	57	.	.	PUNCT
dti-1297	35	1	the	the	DET
dti-1297	35	2	discrepancies	discrepancy	NOUN
dti-1297	35	3	between	between	ADP
dti-1297	35	4	the	the	DET
dti-1297	35	5	studies	study	NOUN
dti-1297	35	6	could	could	AUX
dti-1297	35	7	be	be	AUX
dti-1297	35	8	explained	explain	VERB
dti-1297	35	9	by	by	ADP
dti-1297	35	10	the	the	DET
dti-1297	35	11	limitation	limitation	NOUN
dti-1297	35	12	of	of	ADP
dti-1297	35	13	the	the	DET
dti-1297	35	14	transgenic	transgenic	NOUN
dti-1297	35	15	animal	animal	NOUN
dti-1297	35	16	models	model	NOUN
dti-1297	35	17	as	as	ADP
dti-1297	35	18	representative	representative	NOUN
dti-1297	35	19	of	of	ADP
dti-1297	35	20	complex	complex	ADJ
dti-1297	35	21	diseases	disease	NOUN
dti-1297	35	22	,	,	PUNCT
dti-1297	35	23	and	and	CCONJ
dti-1297	35	24	to	to	PART
dti-1297	35	25	study	study	VERB
dti-1297	35	26	adult	adult	NOUN
dti-1297	35	27	phenotypes	phenotype	NOUN
dti-1297	35	28	,	,	PUNCT
dti-1297	35	29	like	like	ADP
dti-1297	35	30	adult	adult	NOUN
dti-1297	35	31	neurogenesis	neurogenesis	NOUN
dti-1297	35	32	(	(	PUNCT
dti-1297	35	33	dodart	dodart	NOUN
dti-1297	35	34	et	et	PROPN
dti-1297	35	35	al	al	PROPN
dti-1297	35	36	.	.	PROPN
dti-1297	35	37	2002	2002	NUM
dti-1297	35	38	)	)	PUNCT
dti-1297	35	39	.	.	PUNCT
dti-1297	36	1	particularly	particularly	ADV
dti-1297	36	2	,	,	PUNCT
dti-1297	36	3	mutant	mutant	ADJ
dti-1297	36	4	or	or	CCONJ
dti-1297	36	5	defi	defi	NOUN
dti-1297	36	6	cient	cient	NOUN
dti-1297	36	7	mice	mouse	NOUN
dti-1297	36	8	for	for	ADP
dti-1297	36	9	single	single	ADJ
dti-1297	36	10	genes	gene	NOUN
dti-1297	36	11	,	,	PUNCT
dti-1297	36	12	like	like	ADP
dti-1297	36	13	psen1	psen1	NOUN
dti-1297	36	14	and	and	CCONJ
dti-1297	36	15	app	app	PROPN
dti-1297	36	16	,	,	PUNCT
dti-1297	36	17	may	may	AUX
dti-1297	36	18	not	not	PART
dti-1297	36	19	fully	fully	ADV
dti-1297	36	20	reproduce	reproduce	VERB
dti-1297	36	21	the	the	DET
dti-1297	36	22	features	feature	NOUN
dti-1297	36	23	of	of	ADP
dti-1297	36	24	ad	ad	NOUN
dti-1297	36	25	,	,	PUNCT
dti-1297	36	26	associated	associate	VERB
dti-1297	36	27	with	with	ADP
dti-1297	36	28	loss	loss	NOUN
dti-1297	36	29	of	of	ADP
dti-1297	36	30	multiple	multiple	ADJ
dti-1297	36	31	cell	cell	NOUN
dti-1297	36	32	types	type	NOUN
dti-1297	36	33	.	.	PUNCT
dti-1297	37	1	four	four	NUM
dti-1297	37	2	to	to	PART
dti-1297	37	3	10	10	NUM
dti-1297	37	4	%	%	NOUN
dti-1297	37	5	of	of	ADP
dti-1297	37	6	nerve	nerve	NOUN
dti-1297	37	7	cells	cell	NOUN
dti-1297	37	8	in	in	ADP
dti-1297	37	9	regions	region	NOUN
dti-1297	37	10	in	in	ADP
dti-1297	37	11	which	which	PRON
dti-1297	37	12	degeneration	degeneration	NOUN
dti-1297	37	13	occurs	occur	VERB
dti-1297	37	14	in	in	ADP
dti-1297	37	15	ad	ad	NOUN
dti-1297	37	16	,	,	PUNCT
dti-1297	37	17	like	like	ADP
dti-1297	37	18	the	the	DET
dti-1297	37	19	hippocampus	hippocampus	NOUN
dti-1297	37	20	,	,	PUNCT
dti-1297	37	21	are	be	AUX
dti-1297	37	22	tetraploids	tetraploid	NOUN
dti-1297	37	23	(	(	PUNCT
dti-1297	37	24	yang	yang	PROPN
dti-1297	37	25	et	et	PROPN
dti-1297	37	26	al	al	PROPN
dti-1297	37	27	.	.	PROPN
dti-1297	37	28	2001	2001	NUM
dti-1297	37	29	)	)	PUNCT
dti-1297	37	30	.	.	PUNCT
dti-1297	38	1	nerve	nerve	NOUN
dti-1297	38	2	cells	cell	NOUN
dti-1297	38	3	may	may	AUX
dti-1297	38	4	have	have	AUX
dti-1297	38	5	entered	enter	VERB
dti-1297	38	6	the	the	DET
dti-1297	38	7	cell	cell	NOUN
dti-1297	38	8	cycle	cycle	NOUN
dti-1297	38	9	and	and	CCONJ
dti-1297	38	10	underwent	undergo	VERB
dti-1297	38	11	dna	dna	NOUN
dti-1297	38	12	replication	replication	NOUN
dti-1297	38	13	,	,	PUNCT
dti-1297	38	14	but	but	CCONJ
dti-1297	38	15	did	do	AUX
dti-1297	38	16	not	not	PART
dti-1297	38	17	complete	complete	VERB
dti-1297	38	18	the	the	DET
dti-1297	38	19	cell	cell	NOUN
dti-1297	38	20	cycle	cycle	NOUN
dti-1297	38	21	.	.	PUNCT
dti-1297	39	1	it	it	PRON
dti-1297	39	2	is	be	AUX
dti-1297	39	3	proposed	propose	VERB
dti-1297	39	4	that	that	SCONJ
dti-1297	39	5	cell	cell	NOUN
dti-1297	39	6	cycle	cycle	NOUN
dti-1297	39	7	re	re	NOUN
dti-1297	39	8	-	-	NOUN
dti-1297	39	9	entry	entry	NOUN
dti-1297	39	10	and	and	CCONJ
dti-1297	39	11	dna	dna	NOUN
dti-1297	39	12	duplication	duplication	NOUN
dti-1297	39	13	precedes	precede	VERB
dti-1297	39	14	neuronal	neuronal	ADJ
dti-1297	39	15	death	death	NOUN
dti-1297	39	16	in	in	ADP
dti-1297	39	17	degenerating	degenerate	VERB
dti-1297	39	18	regions	region	NOUN
dti-1297	39	19	of	of	ADP
dti-1297	39	20	the	the	DET
dti-1297	39	21	cns	cns	PROPN
dti-1297	39	22	(	(	PUNCT
dti-1297	39	23	herrup	herrup	NOUN
dti-1297	39	24	et	et	PROPN
dti-1297	39	25	al	al	PROPN
dti-1297	39	26	.	.	PROPN
dti-1297	39	27	2004	2004	NUM
dti-1297	39	28	)	)	PUNCT
dti-1297	39	29	.	.	PUNCT
dti-1297	40	1	as	as	SCONJ
dti-1297	40	2	brdu	brdu	NOUN
dti-1297	40	3	incorporates	incorporate	VERB
dti-1297	40	4	dna	dna	NOUN
dti-1297	40	5	of	of	ADP
dti-1297	40	6	dividing	divide	VERB
dti-1297	40	7	cells	cell	NOUN
dti-1297	40	8	during	during	ADP
dti-1297	40	9	the	the	DET
dti-1297	40	10	sphase	sphase	NOUN
dti-1297	40	11	of	of	ADP
dti-1297	40	12	the	the	DET
dti-1297	40	13	cell	cell	NOUN
dti-1297	40	14	cycle	cycle	NOUN
dti-1297	40	15	,	,	PUNCT
dti-1297	40	16	brdu	brdu	NOUN
dti-1297	40	17	labeling	labeling	NOUN
dti-1297	40	18	will	will	AUX
dti-1297	40	19	not	not	PART
dti-1297	40	20	allow	allow	VERB
dti-1297	40	21	to	to	PART
dti-1297	40	22	discriminate	discriminate	VERB
dti-1297	40	23	cell	cell	NOUN
dti-1297	40	24	proliferation	proliferation	NOUN
dti-1297	40	25	versus	versus	ADP
dti-1297	40	26	cell	cell	NOUN
dti-1297	40	27	cycle	cycle	NOUN
dti-1297	40	28	re	re	NOUN
dti-1297	40	29	-	-	NOUN
dti-1297	40	30	entry	entry	NOUN
dti-1297	40	31	and	and	CCONJ
dti-1297	40	32	dna	dna	NOUN
dti-1297	40	33	duplication	duplication	NOUN
dti-1297	40	34	without	without	ADP
dti-1297	40	35	cell	cell	NOUN
dti-1297	40	36	division	division	NOUN
dti-1297	40	37	.	.	PUNCT
dti-1297	41	1	the	the	DET
dti-1297	41	2	existence	existence	NOUN
dti-1297	41	3	of	of	ADP
dti-1297	41	4	aneuploid	aneuploid	PROPN
dti-1297	41	5	cells	cell	NOUN
dti-1297	41	6	may	may	AUX
dti-1297	41	7	account	account	VERB
dti-1297	41	8	for	for	ADP
dti-1297	41	9	some	some	PRON
dti-1297	41	10	of	of	ADP
dti-1297	41	11	the	the	DET
dti-1297	41	12	newly	newly	ADV
dti-1297	41	13	generated	generate	VERB
dti-1297	41	14	neuronal	neuronal	ADJ
dti-1297	41	15	cells	cell	NOUN
dti-1297	41	16	observed	observe	VERB
dti-1297	41	17	using	use	VERB
dti-1297	41	18	brdu	brdu	NOUN
dti-1297	41	19	-	-	PUNCT
dti-1297	41	20	labeling	labeling	NOUN
dti-1297	41	21	in	in	ADP
dti-1297	41	22	experimental	experimental	ADJ
dti-1297	41	23	models	model	NOUN
dti-1297	41	24	of	of	ADP
dti-1297	41	25	ad	ad	NOUN
dti-1297	41	26	.	.	PUNCT
dti-1297	42	1	therefore	therefore	ADV
dti-1297	42	2	,	,	PUNCT
dti-1297	42	3	though	though	SCONJ
dti-1297	42	4	reports	report	NOUN
dti-1297	42	5	suggest	suggest	VERB
dti-1297	42	6	that	that	SCONJ
dti-1297	42	7	neurogenesis	neurogenesis	NOUN
dti-1297	42	8	is	be	AUX
dti-1297	42	9	enhanced	enhance	VERB
dti-1297	42	10	in	in	ADP
dti-1297	42	11	ad	ad	NOUN
dti-1297	42	12	.	.	PUNCT
dti-1297	43	1	this	this	PRON
dti-1297	43	2	remains	remain	VERB
dti-1297	43	3	to	to	PART
dti-1297	43	4	be	be	AUX
dti-1297	43	5	further	far	ADV
dti-1297	43	6	confi	confi	VERB
dti-1297	43	7	rmed	rme	VERB
dti-1297	43	8	in	in	ADP
dti-1297	43	9	the	the	DET
dti-1297	43	10	light	light	NOUN
dti-1297	43	11	of	of	ADP
dti-1297	43	12	recent	recent	ADJ
dti-1297	43	13	data	datum	NOUN
dti-1297	43	14	showing	show	VERB
dti-1297	43	15	the	the	DET
dti-1297	43	16	existence	existence	NOUN
dti-1297	43	17	of	of	ADP
dti-1297	43	18	tetraploid	tetraploid	ADJ
dti-1297	43	19	cells	cell	NOUN
dti-1297	43	20	in	in	ADP
dti-1297	43	21	regions	region	NOUN
dti-1297	43	22	in	in	ADP
dti-1297	43	23	which	which	PRON
dti-1297	43	24	degeneration	degeneration	NOUN
dti-1297	43	25	occurs	occur	VERB
dti-1297	43	26	in	in	ADP
dti-1297	43	27	ad	ad	NOUN
dti-1297	43	28	.	.	PUNCT
dti-1297	44	1	effect	effect	NOUN
dti-1297	44	2	of	of	ADP
dti-1297	44	3	drugs	drug	NOUN
dti-1297	44	4	used	use	VERB
dti-1297	44	5	to	to	PART
dti-1297	44	6	treat	treat	VERB
dti-1297	44	7	ad	ad	NOUN
dti-1297	44	8	on	on	ADP
dti-1297	44	9	neurogenesis	neurogenesis	NOUN
dti-1297	44	10	researchers	researcher	NOUN
dti-1297	44	11	have	have	AUX
dti-1297	44	12	aimed	aim	VERB
dti-1297	44	13	to	to	PART
dti-1297	44	14	identify	identify	VERB
dti-1297	44	15	the	the	DET
dti-1297	44	16	effect	effect	NOUN
dti-1297	44	17	of	of	ADP
dti-1297	44	18	drugs	drug	NOUN
dti-1297	44	19	used	use	VERB
dti-1297	44	20	to	to	PART
dti-1297	44	21	treat	treat	VERB
dti-1297	44	22	ad	ad	NOUN
dti-1297	44	23	on	on	ADP
dti-1297	44	24	neurogenesis	neurogenesis	NOUN
dti-1297	44	25	.	.	PUNCT
dti-1297	45	1	the	the	DET
dti-1297	45	2	effects	effect	NOUN
dti-1297	45	3	of	of	ADP
dti-1297	45	4	tacrine	tacrine	NOUN
dti-1297	45	5	,	,	PUNCT
dti-1297	45	6	galantamine	galantamine	NOUN
dti-1297	45	7	and	and	CCONJ
dti-1297	45	8	memantine	memantine	NOUN
dti-1297	45	9	on	on	ADP
dti-1297	45	10	neurogenesis	neurogenesis	NOUN
dti-1297	45	11	were	be	AUX
dti-1297	45	12	assessed	assess	VERB
dti-1297	45	13	in	in	ADP
dti-1297	45	14	adult	adult	NOUN
dti-1297	45	15	mice	mouse	NOUN
dti-1297	45	16	,	,	PUNCT
dti-1297	45	17	using	use	VERB
dti-1297	45	18	the	the	DET
dti-1297	45	19	brdu	brdu	NOUN
dti-1297	45	20	-	-	PUNCT
dti-1297	45	21	labeling	labeling	NOUN
dti-1297	45	22	paradigm	paradigm	NOUN
dti-1297	45	23	(	(	PUNCT
dti-1297	45	24	jin	jin	NOUN
dti-1297	45	25	et	et	PROPN
dti-1297	45	26	al	al	PROPN
dti-1297	45	27	.	.	PROPN
dti-1297	45	28	2006	2006	NUM
dti-1297	45	29	)	)	PUNCT
dti-1297	45	30	.	.	PUNCT
dti-1297	46	1	the	the	DET
dti-1297	46	2	three	three	NUM
dti-1297	46	3	drugs	drug	NOUN
dti-1297	46	4	increase	increase	VERB
dti-1297	46	5	neurogenesis	neurogenesis	NOUN
dti-1297	46	6	in	in	ADP
dti-1297	46	7	the	the	DET
dti-1297	46	8	dg	dg	NOUN
dti-1297	46	9	and	and	CCONJ
dti-1297	46	10	svz	svz	VERB
dti-1297	46	11	by	by	ADP
dti-1297	46	12	26–45	26–45	NUM
dti-1297	46	13	%	%	NOUN
dti-1297	46	14	,	,	PUNCT
dti-1297	46	15	except	except	SCONJ
dti-1297	46	16	tacrine	tacrine	NOUN
dti-1297	46	17	that	that	PRON
dti-1297	46	18	does	do	AUX
dti-1297	46	19	not	not	PART
dti-1297	46	20	alter	alter	VERB
dti-1297	46	21	brdu	brdu	NOUN
dti-1297	46	22	labeling	labeling	NOUN
dti-1297	46	23	in	in	ADP
dti-1297	46	24	the	the	DET
dti-1297	46	25	dg	dg	NOUN
dti-1297	46	26	.	.	PUNCT
dti-1297	47	1	these	these	DET
dti-1297	47	2	results	result	NOUN
dti-1297	47	3	show	show	VERB
dti-1297	47	4	that	that	SCONJ
dti-1297	47	5	drugs	drug	NOUN
dti-1297	47	6	used	use	VERB
dti-1297	47	7	to	to	PART
dti-1297	47	8	treat	treat	VERB
dti-1297	47	9	ad	ad	NOUN
dti-1297	47	10	increase	increase	NOUN
dti-1297	47	11	neurogenesis	neurogenesis	NOUN
dti-1297	47	12	in	in	ADP
dti-1297	47	13	the	the	DET
dti-1297	47	14	adult	adult	NOUN
dti-1297	47	15	brain	brain	NOUN
dti-1297	47	16	,	,	PUNCT
dti-1297	47	17	which	which	PRON
dti-1297	47	18	may	may	AUX
dti-1297	47	19	contribute	contribute	VERB
dti-1297	47	20	to	to	ADP
dti-1297	47	21	their	their	PRON
dti-1297	47	22	therapeutic	therapeutic	ADJ
dti-1297	47	23	effects	effect	NOUN
dti-1297	47	24	(	(	PUNCT
dti-1297	47	25	jin	jin	NOUN
dti-1297	47	26	et	et	PROPN
dti-1297	47	27	al	al	PROPN
dti-1297	47	28	.	.	PROPN
dti-1297	47	29	2006	2006	NUM
dti-1297	47	30	)	)	PUNCT
dti-1297	47	31	.	.	PUNCT
dti-1297	48	1	neurogenesis	neurogenesis	NOUN
dti-1297	48	2	is	be	AUX
dti-1297	48	3	enhanced	enhance	VERB
dti-1297	48	4	in	in	ADP
dti-1297	48	5	ad	ad	NOUN
dti-1297	48	6	(	(	PUNCT
dti-1297	48	7	jin	jin	NOUN
dti-1297	48	8	et	et	PROPN
dti-1297	48	9	al	al	PROPN
dti-1297	48	10	.	.	PROPN
dti-1297	48	11	2004	2004	NUM
dti-1297	48	12	)	)	PUNCT
dti-1297	48	13	,	,	PUNCT
dti-1297	48	14	and	and	CCONJ
dti-1297	48	15	drugs	drug	NOUN
dti-1297	48	16	used	use	VERB
dti-1297	48	17	to	to	PART
dti-1297	48	18	treat	treat	VERB
dti-1297	48	19	ad	ad	NOUN
dti-1297	48	20	also	also	ADV
dti-1297	48	21	increase	increase	VERB
dti-1297	48	22	neurogenesis	neurogenesis	NOUN
dti-1297	48	23	.	.	PUNCT
dti-1297	49	1	the	the	DET
dti-1297	49	2	function	function	NOUN
dti-1297	49	3	of	of	ADP
dti-1297	49	4	increased	increase	VERB
dti-1297	49	5	neurogenesis	neurogenesis	NOUN
dti-1297	49	6	in	in	ADP
dti-1297	49	7	ad	ad	NOUN
dti-1297	49	8	brain	brain	NOUN
dti-1297	49	9	,	,	PUNCT
dti-1297	49	10	and	and	CCONJ
dti-1297	49	11	by	by	ADP
dti-1297	49	12	drugs	drug	NOUN
dti-1297	49	13	used	use	VERB
dti-1297	49	14	to	to	PART
dti-1297	49	15	treat	treat	VERB
dti-1297	49	16	ad	ad	NOUN
dti-1297	49	17	remain	remain	VERB
dti-1297	49	18	to	to	PART
dti-1297	49	19	be	be	AUX
dti-1297	49	20	elucidated	elucidate	VERB
dti-1297	49	21	.	.	PUNCT
dti-1297	50	1	some	some	DET
dti-1297	50	2	speculations	speculation	NOUN
dti-1297	50	3	can	can	AUX
dti-1297	50	4	be	be	AUX
dti-1297	50	5	raised	raise	VERB
dti-1297	50	6	.	.	PUNCT
dti-1297	51	1	the	the	DET
dti-1297	51	2	increase	increase	NOUN
dti-1297	51	3	neurogenesis	neurogenesis	NOUN
dti-1297	51	4	in	in	ADP
dti-1297	51	5	ad	ad	NOUN
dti-1297	51	6	may	may	AUX
dti-1297	51	7	represent	represent	VERB
dti-1297	51	8	a	a	DET
dti-1297	51	9	regenerative	regenerative	ADJ
dti-1297	51	10	attempt	attempt	NOUN
dti-1297	51	11	by	by	ADP
dti-1297	51	12	the	the	DET
dti-1297	51	13	cns	cns	NOUN
dti-1297	51	14	,	,	PUNCT
dti-1297	51	15	to	to	PART
dti-1297	51	16	compensate	compensate	VERB
dti-1297	51	17	for	for	ADP
dti-1297	51	18	the	the	DET
dti-1297	51	19	loss	loss	NOUN
dti-1297	51	20	of	of	ADP
dti-1297	51	21	nerve	nerve	NOUN
dti-1297	51	22	cells	cell	NOUN
dti-1297	51	23	.	.	PUNCT
dti-1297	52	1	it	it	PRON
dti-1297	52	2	may	may	AUX
dti-1297	52	3	also	also	ADV
dti-1297	52	4	represent	represent	VERB
dti-1297	52	5	a	a	DET
dti-1297	52	6	compensatory	compensatory	ADJ
dti-1297	52	7	process	process	NOUN
dti-1297	52	8	to	to	PART
dti-1297	52	9	increase	increase	VERB
dti-1297	52	10	cns	cns	NOUN
dti-1297	52	11	plasticity	plasticity	NOUN
dti-1297	52	12	in	in	ADP
dti-1297	52	13	the	the	DET
dti-1297	52	14	diseased	diseased	ADJ
dti-1297	52	15	brain	brain	NOUN
dti-1297	52	16	(	(	PUNCT
dti-1297	52	17	taupin	taupin	NOUN
dti-1297	52	18	,	,	PUNCT
dti-1297	52	19	2006	2006	NUM
dti-1297	52	20	)	)	PUNCT
dti-1297	52	21	.	.	PUNCT
dti-1297	53	1	one	one	PRON
dti-1297	53	2	can	can	AUX
dti-1297	53	3	speculate	speculate	VERB
dti-1297	53	4	that	that	SCONJ
dti-1297	53	5	drugs	drug	NOUN
dti-1297	53	6	used	use	VERB
dti-1297	53	7	to	to	PART
dti-1297	53	8	treat	treat	VERB
dti-1297	53	9	ad	ad	NOUN
dti-1297	53	10	would	would	AUX
dti-1297	53	11	then	then	ADV
dti-1297	53	12	attempt	attempt	VERB
dti-1297	53	13	to	to	PART
dti-1297	53	14	amplify	amplify	VERB
dti-1297	53	15	such	such	ADJ
dti-1297	53	16	processes	process	NOUN
dti-1297	53	17	.	.	PUNCT
dti-1297	54	1	the	the	DET
dti-1297	54	2	mechanism	mechanism	NOUN
dti-1297	54	3	of	of	ADP
dti-1297	54	4	action	action	NOUN
dti-1297	54	5	of	of	ADP
dti-1297	54	6	these	these	DET
dti-1297	54	7	drugs	drug	NOUN
dti-1297	54	8	on	on	ADP
dti-1297	54	9	neurogenesis	neurogenesis	NOUN
dti-1297	54	10	remains	remain	VERB
dti-1297	54	11	to	to	PART
dti-1297	54	12	be	be	AUX
dti-1297	54	13	elucidated	elucidate	VERB
dti-1297	54	14	,	,	PUNCT
dti-1297	54	15	as	as	ADV
dti-1297	54	16	well	well	ADV
dti-1297	54	17	.	.	PUNCT
dti-1297	55	1	lesion	lesion	NOUN
dti-1297	55	2	of	of	ADP
dti-1297	55	3	the	the	DET
dti-1297	55	4	cholinergic	cholinergic	ADJ
dti-1297	55	5	forebrain	forebrain	NOUN
dti-1297	55	6	impairs	impair	VERB
dti-1297	55	7	hippocampal	hippocampal	ADJ
dti-1297	55	8	neurogenesis	neurogenesis	NOUN
dti-1297	55	9	in	in	ADP
dti-1297	55	10	adult	adult	NOUN
dti-1297	55	11	rats	rat	NOUN
dti-1297	55	12	and	and	CCONJ
dti-1297	55	13	muscarinic	muscarinic	ADJ
dti-1297	55	14	receptors	receptor	NOUN
dti-1297	55	15	have	have	AUX
dti-1297	55	16	been	be	AUX
dti-1297	55	17	identifi	identifi	PROPN
dti-1297	55	18	ed	ed	NOUN
dti-1297	55	19	on	on	ADP
dti-1297	55	20	newly	newly	ADV
dti-1297	55	21	generated	generate	VERB
dti-1297	55	22	neuronal	neuronal	ADJ
dti-1297	55	23	cells	cell	NOUN
dti-1297	55	24	in	in	ADP
dti-1297	55	25	the	the	DET
dti-1297	55	26	sgz	sgz	PROPN
dti-1297	55	27	and	and	CCONJ
dti-1297	55	28	svz	svz	PROPN
dti-1297	55	29	.	.	PUNCT
dti-1297	56	1	this	this	PRON
dti-1297	56	2	suggests	suggest	VERB
dti-1297	56	3	that	that	SCONJ
dti-1297	56	4	the	the	DET
dti-1297	56	5	cholinergic	cholinergic	ADJ
dti-1297	56	6	pathway	pathway	NOUN
dti-1297	56	7	promotes	promote	VERB
dti-1297	56	8	neurogenesis	neurogenesis	NOUN
dti-1297	56	9	(	(	PUNCT
dti-1297	56	10	cooper	cooper	NOUN
dti-1297	56	11	-	-	PUNCT
dti-1297	56	12	kuhn	kuhn	PROPN
dti-1297	56	13	et	et	PROPN
dti-1297	56	14	al	al	PROPN
dti-1297	56	15	.	.	PROPN
dti-1297	56	16	2004	2004	NUM
dti-1297	56	17	;	;	PUNCT
dti-1297	56	18	mohapel	mohapel	NOUN
dti-1297	56	19	et	et	PROPN
dti-1297	56	20	al	al	PROPN
dti-1297	56	21	.	.	PROPN
dti-1297	56	22	2005	2005	NUM
dti-1297	56	23	)	)	PUNCT
dti-1297	56	24	.	.	PUNCT
dti-1297	57	1	since	since	SCONJ
dti-1297	57	2	ache	ache	NOUN
dti-1297	57	3	inhibitors	inhibitor	NOUN
dti-1297	57	4	are	be	AUX
dti-1297	57	5	thought	think	VERB
dti-1297	57	6	to	to	PART
dti-1297	57	7	improve	improve	VERB
dti-1297	57	8	cognitive	cognitive	ADJ
dti-1297	57	9	function	function	NOUN
dti-1297	57	10	by	by	ADP
dti-1297	57	11	enhancing	enhance	VERB
dti-1297	57	12	cholinergic	cholinergic	ADJ
dti-1297	57	13	neurotransmission	neurotransmission	NOUN
dti-1297	57	14	in	in	ADP
dti-1297	57	15	affected	affect	VERB
dti-1297	57	16	brain	brain	NOUN
dti-1297	57	17	regions	region	NOUN
dti-1297	57	18	of	of	ADP
dti-1297	57	19	ad	ad	NOUN
dti-1297	57	20	and	and	CCONJ
dti-1297	57	21	,	,	PUNCT
dti-1297	57	22	tacrine	tacrine	NOUN
dti-1297	57	23	,	,	PUNCT
dti-1297	57	24	galantamine	galantamine	NOUN
dti-1297	57	25	may	may	AUX
dti-1297	57	26	promote	promote	VERB
dti-1297	57	27	neurogenesis	neurogenesis	NOUN
dti-1297	57	28	through	through	ADP
dti-1297	57	29	a	a	DET
dti-1297	57	30	similar	similar	ADJ
dti-1297	57	31	mechanism	mechanism	NOUN
dti-1297	57	32	.	.	PUNCT
dti-1297	58	1	the	the	DET
dti-1297	58	2	reason	reason	NOUN
dti-1297	58	3	why	why	SCONJ
dti-1297	58	4	tacrine	tacrine	NOUN
dti-1297	58	5	that	that	PRON
dti-1297	58	6	do	do	AUX
dti-1297	58	7	not	not	PART
dti-1297	58	8	alter	alter	VERB
dti-1297	58	9	brdu	brdu	NOUN
dti-1297	58	10	labeling	labeling	NOUN
dti-1297	58	11	in	in	ADP
dti-1297	58	12	the	the	DET
dti-1297	58	13	dg	dg	NOUN
dti-1297	58	14	remains	remain	VERB
dti-1297	58	15	to	to	PART
dti-1297	58	16	be	be	AUX
dti-1297	58	17	further	far	ADV
dti-1297	58	18	investigated	investigate	VERB
dti-1297	58	19	.	.	PUNCT
dti-1297	59	1	nmda	nmda	ADJ
dti-1297	59	2	receptor	receptor	NOUN
dti-1297	59	3	antagonists	antagonist	NOUN
dti-1297	59	4	on	on	ADP
dti-1297	59	5	the	the	DET
dti-1297	59	6	one	one	NUM
dti-1297	59	7	hand	hand	NOUN
dti-1297	59	8	promote	promote	VERB
dti-1297	59	9	neurodegeneration	neurodegeneration	NOUN
dti-1297	59	10	(	(	PUNCT
dti-1297	59	11	ikonomidou	ikonomidou	NOUN
dti-1297	59	12	et	et	PROPN
dti-1297	59	13	al	al	PROPN
dti-1297	59	14	.	.	PROPN
dti-1297	59	15	1999	1999	NUM
dti-1297	59	16	)	)	PUNCT
dti-1297	59	17	.	.	PUNCT
dti-1297	60	1	on	on	ADP
dti-1297	60	2	the	the	DET
dti-1297	60	3	other	other	ADJ
dti-1297	60	4	hand	hand	NOUN
dti-1297	60	5	,	,	PUNCT
dti-1297	60	6	they	they	PRON
dti-1297	60	7	promote	promote	VERB
dti-1297	60	8	neurogenesis	neurogenesis	NOUN
dti-1297	60	9	in	in	ADP
dti-1297	60	10	the	the	DET
dti-1297	60	11	adult	adult	NOUN
dti-1297	60	12	brain	brain	NOUN
dti-1297	60	13	(	(	PUNCT
dti-1297	60	14	cameron	cameron	PROPN
dti-1297	60	15	et	et	PROPN
dti-1297	60	16	al	al	PROPN
dti-1297	60	17	.	.	PROPN
dti-1297	60	18	1995	1995	NUM
dti-1297	60	19	,	,	PUNCT
dti-1297	60	20	1998	1998	NUM
dti-1297	60	21	;	;	PUNCT
dti-1297	60	22	gould	gould	PROPN
dti-1297	60	23	et	et	PROPN
dti-1297	60	24	al	al	PROPN
dti-1297	60	25	.	.	PROPN
dti-1297	60	26	1997	1997	NUM
dti-1297	60	27	;	;	PUNCT
dti-1297	60	28	nacher	nacher	ADV
dti-1297	60	29	et	et	PROPN
dti-1297	60	30	al	al	PROPN
dti-1297	60	31	.	.	PROPN
dti-1297	60	32	2001	2001	NUM
dti-1297	60	33	,	,	PUNCT
dti-1297	60	34	2003	2003	NUM
dti-1297	60	35	)	)	PUNCT
dti-1297	60	36	.	.	PUNCT
dti-1297	61	1	therefore	therefore	ADV
dti-1297	61	2	,	,	PUNCT
dti-1297	61	3	the	the	DET
dti-1297	61	4	therapeutic	therapeutic	ADJ
dti-1297	61	5	effect	effect	NOUN
dti-1297	61	6	of	of	ADP
dti-1297	61	7	memantine	memantine	NOUN
dti-1297	61	8	,	,	PUNCT
dti-1297	61	9	an	an	DET
dti-1297	61	10	nmda	nmda	ADJ
dti-1297	61	11	-	-	PUNCT
dti-1297	61	12	glutamate	glutamate	ADJ
dti-1297	61	13	receptor	receptor	NOUN
dti-1297	61	14	antagonist	antagonist	NOUN
dti-1297	61	15	,	,	PUNCT
dti-1297	61	16	in	in	ADP
dti-1297	61	17	ad	ad	NOUN
dti-1297	61	18	may	may	AUX
dti-1297	61	19	also	also	ADV
dti-1297	61	20	be	be	AUX
dti-1297	61	21	mediated	mediate	VERB
dti-1297	61	22	through	through	ADP
dti-1297	61	23	stimulation	stimulation	NOUN
dti-1297	61	24	of	of	ADP
dti-1297	61	25	neurogenesis	neurogenesis	NOUN
dti-1297	61	26	.	.	PUNCT
dti-1297	62	1	these	these	DET
dti-1297	62	2	hypotheses	hypothesis	NOUN
dti-1297	62	3	and	and	CCONJ
dti-1297	62	4	the	the	DET
dti-1297	62	5	mechanisms	mechanism	NOUN
dti-1297	62	6	of	of	ADP
dti-1297	62	7	action	action	NOUN
dti-1297	62	8	of	of	ADP
dti-1297	62	9	drugs	drug	NOUN
dti-1297	62	10	used	use	VERB
dti-1297	62	11	for	for	ADP
dti-1297	62	12	the	the	DET
dti-1297	62	13	treatment	treatment	NOUN
dti-1297	62	14	of	of	ADP
dti-1297	62	15	ad	ad	NOUN
dti-1297	62	16	remain	remain	VERB
dti-1297	62	17	to	to	PART
dti-1297	62	18	be	be	AUX
dti-1297	62	19	confi	confi	ADJ
dti-1297	62	20	rmed	rme	VERB
dti-1297	62	21	,	,	PUNCT
dti-1297	62	22	and	and	CCONJ
dti-1297	62	23	investigated	investigate	VERB
dti-1297	62	24	.	.	PUNCT
dti-1297	63	1	stem	stem	NOUN
dti-1297	63	2	cell	cell	NOUN
dti-1297	63	3	therapy	therapy	NOUN
dti-1297	63	4	for	for	ADP
dti-1297	63	5	the	the	DET
dti-1297	63	6	treatment	treatment	NOUN
dti-1297	63	7	of	of	ADP
dti-1297	63	8	ad	ad	NOUN
dti-1297	63	9	because	because	SCONJ
dti-1297	63	10	ad	ad	NOUN
dti-1297	63	11	is	be	AUX
dti-1297	63	12	associated	associate	VERB
dti-1297	63	13	with	with	ADP
dti-1297	63	14	the	the	DET
dti-1297	63	15	loss	loss	NOUN
dti-1297	63	16	of	of	ADP
dti-1297	63	17	nerve	nerve	NOUN
dti-1297	63	18	cells	cell	NOUN
dti-1297	63	19	,	,	PUNCT
dti-1297	63	20	cellular	cellular	ADJ
dti-1297	63	21	therapy	therapy	NOUN
dti-1297	63	22	is	be	AUX
dti-1297	63	23	considered	consider	VERB
dti-1297	63	24	for	for	ADP
dti-1297	63	25	the	the	DET
dti-1297	63	26	drug	drug	NOUN
dti-1297	63	27	target	target	NOUN
dti-1297	63	28	insights	insight	NOUN
dti-1297	63	29	2006	2006	NUM
dti-1297	63	30	:	:	PUNCT
dti-1297	63	31	1	1	NUM
dti-1297	63	32	3	3	NUM
dti-1297	63	33	neurogenesis	neurogenesis	NOUN
dti-1297	63	34	and	and	CCONJ
dti-1297	63	35	ad	ad	NOUN
dti-1297	63	36	treatment	treatment	NOUN
dti-1297	63	37	of	of	ADP
dti-1297	63	38	this	this	DET
dti-1297	63	39	disease	disease	NOUN
dti-1297	63	40	.	.	PUNCT
dti-1297	64	1	with	with	ADP
dti-1297	64	2	the	the	DET
dti-1297	64	3	recent	recent	ADJ
dti-1297	64	4	evidence	evidence	NOUN
dti-1297	64	5	that	that	SCONJ
dti-1297	64	6	neurogenesis	neurogenesis	NOUN
dti-1297	64	7	occurs	occur	VERB
dti-1297	64	8	in	in	ADP
dti-1297	64	9	the	the	DET
dti-1297	64	10	adult	adult	NOUN
dti-1297	64	11	brain	brain	NOUN
dti-1297	64	12	and	and	CCONJ
dti-1297	64	13	nscs	nscs	PROPN
dti-1297	64	14	reside	reside	VERB
dti-1297	64	15	in	in	ADP
dti-1297	64	16	the	the	DET
dti-1297	64	17	adult	adult	NOUN
dti-1297	64	18	cns	cns	NOUN
dti-1297	64	19	,	,	PUNCT
dti-1297	64	20	new	new	ADJ
dti-1297	64	21	strategies	strategy	NOUN
dti-1297	64	22	for	for	ADP
dti-1297	64	23	the	the	DET
dti-1297	64	24	treatment	treatment	NOUN
dti-1297	64	25	of	of	ADP
dti-1297	64	26	neurodegenerative	neurodegenerative	ADJ
dti-1297	64	27	diseases	disease	NOUN
dti-1297	64	28	,	,	PUNCT
dti-1297	64	29	and	and	CCONJ
dti-1297	64	30	particularly	particularly	ADV
dti-1297	64	31	ad	ad	NOUN
dti-1297	64	32	,	,	PUNCT
dti-1297	64	33	are	be	AUX
dti-1297	64	34	being	be	AUX
dti-1297	64	35	considered	consider	VERB
dti-1297	64	36	and	and	CCONJ
dti-1297	64	37	are	be	AUX
dti-1297	64	38	promising	promise	VERB
dti-1297	64	39	:	:	PUNCT
dti-1297	64	40	the	the	DET
dti-1297	64	41	transplantation	transplantation	NOUN
dti-1297	64	42	of	of	ADP
dti-1297	64	43	adult	adult	NOUN
dti-1297	64	44	-	-	PUNCT
dti-1297	64	45	derived	derive	VERB
dti-1297	64	46	neural	neural	ADJ
dti-1297	64	47	progenitor	progenitor	NOUN
dti-1297	64	48	and	and	CCONJ
dti-1297	64	49	stem	stem	NOUN
dti-1297	64	50	cells	cell	NOUN
dti-1297	64	51	,	,	PUNCT
dti-1297	64	52	and	and	CCONJ
dti-1297	64	53	the	the	DET
dti-1297	64	54	stimulation	stimulation	NOUN
dti-1297	64	55	of	of	ADP
dti-1297	64	56	endogenous	endogenous	ADJ
dti-1297	64	57	neural	neural	ADJ
dti-1297	64	58	progenitor	progenitor	NOUN
dti-1297	64	59	cells	cell	NOUN
dti-1297	64	60	.	.	PUNCT
dti-1297	65	1	experimental	experimental	ADJ
dti-1297	65	2	studies	study	NOUN
dti-1297	65	3	reveal	reveal	VERB
dti-1297	65	4	that	that	SCONJ
dti-1297	65	5	adult	adult	NOUN
dti-1297	65	6	derived	derive	VERB
dti-1297	65	7	-	-	PUNCT
dti-1297	65	8	neural	neural	ADJ
dti-1297	65	9	progenitor	progenitor	NOUN
dti-1297	65	10	and	and	CCONJ
dti-1297	65	11	stem	stem	NOUN
dti-1297	65	12	cells	cell	NOUN
dti-1297	65	13	engraft	engraft	VERB
dti-1297	65	14	the	the	DET
dti-1297	65	15	host	host	NOUN
dti-1297	65	16	tissues	tissue	NOUN
dti-1297	65	17	(	(	PUNCT
dti-1297	65	18	gage	gage	NOUN
dti-1297	65	19	et	et	PROPN
dti-1297	65	20	al	al	PROPN
dti-1297	65	21	.	.	PROPN
dti-1297	65	22	1995	1995	NUM
dti-1297	65	23	;	;	PUNCT
dti-1297	65	24	shihabuddin	shihabuddin	NOUN
dti-1297	65	25	et	et	PROPN
dti-1297	65	26	al	al	PROPN
dti-1297	65	27	.	.	PROPN
dti-1297	65	28	2000	2000	NUM
dti-1297	65	29	)	)	PUNCT
dti-1297	65	30	,	,	PUNCT
dti-1297	65	31	and	and	CCONJ
dti-1297	65	32	promote	promote	VERB
dti-1297	65	33	functional	functional	ADJ
dti-1297	65	34	recovery	recovery	NOUN
dti-1297	65	35	in	in	ADP
dti-1297	65	36	animal	animal	NOUN
dti-1297	65	37	models	model	NOUN
dti-1297	65	38	of	of	ADP
dti-1297	65	39	neurodegenerative	neurodegenerative	ADJ
dti-1297	65	40	diseases	disease	NOUN
dti-1297	65	41	,	,	PUNCT
dti-1297	65	42	like	like	ADP
dti-1297	65	43	multiple	multiple	ADJ
dti-1297	65	44	sclerosis	sclerosis	NOUN
dti-1297	65	45	(	(	PUNCT
dti-1297	65	46	pluchino	pluchino	PROPN
dti-1297	65	47	et	et	PROPN
dti-1297	65	48	al	al	PROPN
dti-1297	65	49	.	.	PROPN
dti-1297	65	50	2003	2003	NUM
dti-1297	65	51	)	)	PUNCT
dti-1297	65	52	.	.	PUNCT
dti-1297	66	1	in	in	ADP
dti-1297	66	2	ad	ad	NOUN
dti-1297	66	3	,	,	PUNCT
dti-1297	66	4	like	like	ADP
dti-1297	66	5	multiple	multiple	ADJ
dti-1297	66	6	sclerosis	sclerosis	NOUN
dti-1297	66	7	,	,	PUNCT
dti-1297	66	8	the	the	DET
dti-1297	66	9	degeneration	degeneration	NOUN
dti-1297	66	10	is	be	AUX
dti-1297	66	11	widespread	widespread	ADJ
dti-1297	66	12	,	,	PUNCT
dti-1297	66	13	therefore	therefore	ADV
dti-1297	66	14	direct	direct	ADJ
dti-1297	66	15	transplantation	transplantation	NOUN
dti-1297	66	16	of	of	ADP
dti-1297	66	17	neural	neural	ADJ
dti-1297	66	18	progenitor	progenitor	NOUN
dti-1297	66	19	and	and	CCONJ
dti-1297	66	20	stem	stem	NOUN
dti-1297	66	21	cells	cell	NOUN
dti-1297	66	22	in	in	ADP
dti-1297	66	23	the	the	DET
dti-1297	66	24	brain	brain	NOUN
dti-1297	66	25	may	may	AUX
dti-1297	66	26	not	not	PART
dti-1297	66	27	offer	offer	VERB
dti-1297	66	28	an	an	DET
dti-1297	66	29	optimum	optimum	ADJ
dti-1297	66	30	strategy	strategy	NOUN
dti-1297	66	31	for	for	ADP
dti-1297	66	32	treating	treat	VERB
dti-1297	66	33	these	these	DET
dti-1297	66	34	diseases	disease	NOUN
dti-1297	66	35	.	.	PUNCT
dti-1297	67	1	neural	neural	ADJ
dti-1297	67	2	progenitor	progenitor	NOUN
dti-1297	67	3	and	and	CCONJ
dti-1297	67	4	stem	stem	NOUN
dti-1297	67	5	cell	cell	NOUN
dti-1297	67	6	migrate	migrate	NOUN
dti-1297	67	7	to	to	ADP
dti-1297	67	8	diseased	diseased	ADJ
dti-1297	67	9	and	and	CCONJ
dti-1297	67	10	injured	injure	VERB
dti-1297	67	11	sites	site	NOUN
dti-1297	67	12	in	in	ADP
dti-1297	67	13	the	the	DET
dti-1297	67	14	brain	brain	NOUN
dti-1297	67	15	,	,	PUNCT
dti-1297	67	16	when	when	SCONJ
dti-1297	67	17	administered	administer	VERB
dti-1297	67	18	by	by	ADP
dti-1297	67	19	systemic	systemic	ADJ
dti-1297	67	20	injection	injection	NOUN
dti-1297	67	21	(	(	PUNCT
dti-1297	67	22	macklis	macklis	PROPN
dti-1297	67	23	et	et	PROPN
dti-1297	67	24	al	al	PROPN
dti-1297	67	25	.	.	PROPN
dti-1297	67	26	1993	1993	NUM
dti-1297	67	27	;	;	PUNCT
dti-1297	67	28	pluchino	pluchino	PROPN
dti-1297	67	29	et	et	PROPN
dti-1297	67	30	al	al	PROPN
dti-1297	67	31	.	.	PROPN
dti-1297	67	32	2003	2003	NUM
dti-1297	67	33	;	;	PUNCT
dti-1297	67	34	fujiwara	fujiwara	PROPN
dti-1297	67	35	et	et	PROPN
dti-1297	67	36	al	al	PROPN
dti-1297	67	37	.	.	PROPN
dti-1297	67	38	2004	2004	NUM
dti-1297	67	39	)	)	PUNCT
dti-1297	67	40	.	.	PUNCT
dti-1297	68	1	such	such	ADJ
dti-1297	68	2	ways	way	NOUN
dti-1297	68	3	of	of	ADP
dti-1297	68	4	delivering	deliver	VERB
dti-1297	68	5	neural	neural	ADJ
dti-1297	68	6	progenitor	progenitor	NOUN
dti-1297	68	7	and	and	CCONJ
dti-1297	68	8	stem	stem	NOUN
dti-1297	68	9	cells	cell	NOUN
dti-1297	68	10	,	,	PUNCT
dti-1297	68	11	that	that	PRON
dti-1297	68	12	are	be	AUX
dti-1297	68	13	also	also	ADV
dti-1297	68	14	noninvasive	noninvasive	ADJ
dti-1297	68	15	,	,	PUNCT
dti-1297	68	16	may	may	AUX
dti-1297	68	17	prove	prove	VERB
dti-1297	68	18	to	to	PART
dti-1297	68	19	be	be	AUX
dti-1297	68	20	valuable	valuable	ADJ
dti-1297	68	21	for	for	ADP
dti-1297	68	22	the	the	DET
dti-1297	68	23	treatment	treatment	NOUN
dti-1297	68	24	of	of	ADP
dti-1297	68	25	ad	ad	NOUN
dti-1297	68	26	.	.	PUNCT
dti-1297	69	1	neurogenesis	neurogenesis	NOUN
dti-1297	69	2	is	be	AUX
dti-1297	69	3	enhanced	enhance	VERB
dti-1297	69	4	in	in	ADP
dti-1297	69	5	the	the	DET
dti-1297	69	6	diseased	diseased	ADJ
dti-1297	69	7	brain	brain	NOUN
dti-1297	69	8	,	,	PUNCT
dti-1297	69	9	particularly	particularly	ADV
dti-1297	69	10	in	in	ADP
dti-1297	69	11	ad	ad	NOUN
dti-1297	69	12	(	(	PUNCT
dti-1297	69	13	jin	jin	NOUN
dti-1297	69	14	et	et	PROPN
dti-1297	69	15	al	al	PROPN
dti-1297	69	16	.	.	PROPN
dti-1297	69	17	2004a	2004a	NUM
dti-1297	69	18	)	)	PUNCT
dti-1297	69	19	.	.	PUNCT
dti-1297	70	1	this	this	PRON
dti-1297	70	2	suggests	suggest	VERB
dti-1297	70	3	that	that	SCONJ
dti-1297	70	4	the	the	DET
dti-1297	70	5	brain	brain	NOUN
dti-1297	70	6	has	have	VERB
dti-1297	70	7	the	the	DET
dti-1297	70	8	potential	potential	NOUN
dti-1297	70	9	to	to	ADP
dti-1297	70	10	self	self	NOUN
dti-1297	70	11	-	-	PUNCT
dti-1297	70	12	repair	repair	NOUN
dti-1297	70	13	,	,	PUNCT
dti-1297	70	14	and	and	CCONJ
dti-1297	70	15	that	that	SCONJ
dti-1297	70	16	endogenous	endogenous	ADJ
dti-1297	70	17	progenitor	progenitor	NOUN
dti-1297	70	18	cells	cell	NOUN
dti-1297	70	19	may	may	AUX
dti-1297	70	20	be	be	AUX
dti-1297	70	21	recruited	recruit	VERB
dti-1297	70	22	to	to	PART
dti-1297	70	23	replace	replace	VERB
dti-1297	70	24	degenerated	degenerated	ADJ
dti-1297	70	25	nerve	nerve	NOUN
dti-1297	70	26	cells	cell	NOUN
dti-1297	70	27	and	and	CCONJ
dti-1297	70	28	promote	promote	VERB
dti-1297	70	29	functional	functional	ADJ
dti-1297	70	30	recovery	recovery	NOUN
dti-1297	70	31	.	.	PUNCT
dti-1297	71	1	future	future	ADJ
dti-1297	71	2	studies	study	NOUN
dti-1297	71	3	will	will	AUX
dti-1297	71	4	aim	aim	VERB
dti-1297	71	5	at	at	ADP
dti-1297	71	6	identifying	identify	VERB
dti-1297	71	7	factors	factor	NOUN
dti-1297	71	8	that	that	PRON
dti-1297	71	9	promote	promote	VERB
dti-1297	71	10	neurogeneis	neurogeneis	NOUN
dti-1297	71	11	in	in	ADP
dti-1297	71	12	ad	ad	NOUN
dti-1297	71	13	,	,	PUNCT
dti-1297	71	14	as	as	ADP
dti-1297	71	15	candidates	candidate	NOUN
dti-1297	71	16	for	for	ADP
dti-1297	71	17	cellular	cellular	ADJ
dti-1297	71	18	therapy	therapy	NOUN
dti-1297	71	19	.	.	PUNCT
dti-1297	72	1	conclusion	conclusion	NOUN
dti-1297	72	2	neurogenesis	neurogenesis	NOUN
dti-1297	72	3	is	be	AUX
dti-1297	72	4	enhanced	enhance	VERB
dti-1297	72	5	in	in	ADP
dti-1297	72	6	ad	ad	NOUN
dti-1297	72	7	,	,	PUNCT
dti-1297	72	8	and	and	CCONJ
dti-1297	72	9	drugs	drug	NOUN
dti-1297	72	10	used	use	VERB
dti-1297	72	11	to	to	PART
dti-1297	72	12	treat	treat	VERB
dti-1297	72	13	ad	ad	NOUN
dti-1297	72	14	,	,	PUNCT
dti-1297	72	15	though	though	SCONJ
dti-1297	72	16	acting	act	VERB
dti-1297	72	17	through	through	ADP
dti-1297	72	18	different	different	ADJ
dti-1297	72	19	mechanisms	mechanism	NOUN
dti-1297	72	20	of	of	ADP
dti-1297	72	21	action	action	NOUN
dti-1297	72	22	,	,	PUNCT
dti-1297	72	23	increase	increase	NOUN
dti-1297	72	24	neurogenesis	neurogenesis	NOUN
dti-1297	72	25	.	.	PUNCT
dti-1297	73	1	this	this	PRON
dti-1297	73	2	may	may	AUX
dti-1297	73	3	contribute	contribute	VERB
dti-1297	73	4	to	to	ADP
dti-1297	73	5	their	their	PRON
dti-1297	73	6	therapeutic	therapeutic	ADJ
dti-1297	73	7	effects	effect	NOUN
dti-1297	73	8	.	.	PUNCT
dti-1297	74	1	santarelli	santarelli	PROPN
dti-1297	74	2	et	et	PROPN
dti-1297	74	3	al	al	PROPN
dti-1297	74	4	.	.	PROPN
dti-1297	75	1	(	(	PUNCT
dti-1297	75	2	2003	2003	NUM
dti-1297	75	3	)	)	PUNCT
dti-1297	75	4	reported	report	VERB
dti-1297	75	5	using	use	VERB
dti-1297	75	6	a	a	DET
dti-1297	75	7	combination	combination	NOUN
dti-1297	75	8	of	of	ADP
dti-1297	75	9	mouse	mouse	NOUN
dti-1297	75	10	models	model	NOUN
dti-1297	75	11	and	and	CCONJ
dti-1297	75	12	x	x	NOUN
dti-1297	75	13	-	-	NOUN
dti-1297	75	14	irradiation	irradiation	NOUN
dti-1297	75	15	-to	-to	INTJ
dti-1297	75	16	inhibit	inhibit	VERB
dti-1297	75	17	neurogenesis-	neurogenesis-	NOUN
dti-1297	75	18	,	,	PUNCT
dti-1297	75	19	that	that	PRON
dti-1297	75	20	antidepressants	antidepressant	VERB
dti-1297	75	21	,	,	PUNCT
dti-1297	75	22	like	like	ADP
dti-1297	75	23	fluoxetine	fluoxetine	NOUN
dti-1297	75	24	,	,	PUNCT
dti-1297	75	25	increase	increase	VERB
dti-1297	75	26	hippocampal	hippocampal	ADJ
dti-1297	75	27	neurogenesis	neurogenesis	NOUN
dti-1297	75	28	,	,	PUNCT
dti-1297	75	29	which	which	PRON
dti-1297	75	30	contribute	contribute	VERB
dti-1297	75	31	to	to	ADP
dti-1297	75	32	their	their	PRON
dti-1297	75	33	behavioral	behavioral	ADJ
dti-1297	75	34	activities	activity	NOUN
dti-1297	75	35	.	.	PUNCT
dti-1297	76	1	meshi	meshi	PROPN
dti-1297	76	2	et	et	PROPN
dti-1297	76	3	al	al	PROPN
dti-1297	76	4	.	.	PROPN
dti-1297	76	5	(	(	PUNCT
dti-1297	76	6	2006	2006	NUM
dti-1297	76	7	)	)	PUNCT
dti-1297	76	8	,	,	PUNCT
dti-1297	76	9	using	use	VERB
dti-1297	76	10	the	the	DET
dti-1297	76	11	same	same	ADJ
dti-1297	76	12	approaches	approach	NOUN
dti-1297	76	13	,	,	PUNCT
dti-1297	76	14	reported	report	VERB
dti-1297	76	15	that	that	SCONJ
dti-1297	76	16	neurogenesis	neurogenesis	NOUN
dti-1297	76	17	does	do	AUX
dti-1297	76	18	not	not	PART
dti-1297	76	19	mediate	mediate	VERB
dti-1297	76	20	the	the	DET
dti-1297	76	21	behavioral	behavioral	ADJ
dti-1297	76	22	effects	effect	NOUN
dti-1297	76	23	of	of	ADP
dti-1297	76	24	environmental	environmental	ADJ
dti-1297	76	25	enrichment	enrichment	NOUN
dti-1297	76	26	(	(	PUNCT
dti-1297	76	27	meshi	meshi	PROPN
dti-1297	76	28	et	et	PROPN
dti-1297	76	29	al	al	PROPN
dti-1297	76	30	.	.	PROPN
dti-1297	76	31	2006	2006	NUM
dti-1297	76	32	)	)	PUNCT
dti-1297	76	33	.	.	PUNCT
dti-1297	77	1	inhibition	inhibition	NOUN
dti-1297	77	2	of	of	ADP
dti-1297	77	3	neurogenesis	neurogenesis	NOUN
dti-1297	77	4	is	be	AUX
dti-1297	77	5	therefore	therefore	ADV
dti-1297	77	6	key	key	ADJ
dti-1297	77	7	to	to	PART
dti-1297	77	8	determine	determine	VERB
dti-1297	77	9	causal	causal	ADJ
dti-1297	77	10	relationship	relationship	NOUN
dti-1297	77	11	between	between	ADP
dti-1297	77	12	neurogenesis	neurogenesis	NOUN
dti-1297	77	13	and	and	CCONJ
dti-1297	77	14	a	a	DET
dti-1297	77	15	physiological	physiological	ADJ
dti-1297	77	16	or	or	CCONJ
dti-1297	77	17	pathological	pathological	ADJ
dti-1297	77	18	function	function	NOUN
dti-1297	77	19	.	.	PUNCT
dti-1297	78	1	therefore	therefore	ADV
dti-1297	78	2	,	,	PUNCT
dti-1297	78	3	it	it	PRON
dti-1297	78	4	remains	remain	VERB
dti-1297	78	5	to	to	PART
dti-1297	78	6	evaluate	evaluate	VERB
dti-1297	78	7	the	the	DET
dti-1297	78	8	consequence	consequence	NOUN
dti-1297	78	9	of	of	ADP
dti-1297	78	10	inhibiting	inhibit	VERB
dti-1297	78	11	neurogenesis	neurogenesis	NOUN
dti-1297	78	12	on	on	ADP
dti-1297	78	13	the	the	DET
dti-1297	78	14	effect	effect	NOUN
dti-1297	78	15	of	of	ADP
dti-1297	78	16	drugs	drug	NOUN
dti-1297	78	17	used	use	VERB
dti-1297	78	18	for	for	ADP
dti-1297	78	19	the	the	DET
dti-1297	78	20	treatment	treatment	NOUN
dti-1297	78	21	of	of	ADP
dti-1297	78	22	ad	ad	NOUN
dti-1297	78	23	,	,	PUNCT
dti-1297	78	24	to	to	PART
dti-1297	78	25	establish	establish	VERB
dti-1297	78	26	a	a	DET
dti-1297	78	27	causal	causal	ADJ
dti-1297	78	28	relationship	relationship	NOUN
dti-1297	78	29	between	between	ADP
dti-1297	78	30	their	their	PRON
dti-1297	78	31	therapeutic	therapeutic	ADJ
dti-1297	78	32	effects	effect	NOUN
dti-1297	78	33	and	and	CCONJ
dti-1297	78	34	the	the	DET
dti-1297	78	35	stimulation	stimulation	NOUN
dti-1297	78	36	of	of	ADP
dti-1297	78	37	neurogenesis	neurogenesis	NOUN
dti-1297	78	38	.	.	PUNCT
dti-1297	79	1	nonetheless	nonetheless	ADV
dti-1297	79	2	,	,	PUNCT
dti-1297	79	3	the	the	DET
dti-1297	79	4	evidence	evidence	NOUN
dti-1297	79	5	that	that	PRON
dti-1297	79	6	drugs	drug	NOUN
dti-1297	79	7	used	use	VERB
dti-1297	79	8	to	to	PART
dti-1297	79	9	treat	treat	VERB
dti-1297	79	10	ad	ad	NOUN
dti-1297	79	11	positively	positively	ADV
dti-1297	79	12	regulate	regulate	VERB
dti-1297	79	13	neurogenesis	neurogenesis	NOUN
dti-1297	79	14	may	may	AUX
dti-1297	79	15	lead	lead	VERB
dti-1297	79	16	to	to	ADP
dti-1297	79	17	new	new	ADJ
dti-1297	79	18	drugs	drug	NOUN
dti-1297	79	19	design	design	NOUN
dti-1297	79	20	,	,	PUNCT
dti-1297	79	21	and	and	CCONJ
dti-1297	79	22	new	new	ADJ
dti-1297	79	23	strategies	strategy	NOUN
dti-1297	79	24	to	to	PART
dti-1297	79	25	treat	treat	VERB
dti-1297	79	26	ad	ad	NOUN
dti-1297	79	27	.	.	PUNCT
dti-1297	80	1	to	to	ADP
dti-1297	80	2	this	this	DET
dti-1297	80	3	aim	aim	NOUN
dti-1297	80	4	,	,	PUNCT
dti-1297	80	5	unraveling	unravel	VERB
dti-1297	80	6	the	the	DET
dti-1297	80	7	cellular	cellular	ADJ
dti-1297	80	8	and	and	CCONJ
dti-1297	80	9	molecular	molecular	ADJ
dti-1297	80	10	mechanisms	mechanism	NOUN
dti-1297	80	11	of	of	ADP
dti-1297	80	12	action	action	NOUN
dti-1297	80	13	of	of	ADP
dti-1297	80	14	drugs	drug	NOUN
dti-1297	80	15	to	to	PART
dti-1297	80	16	treat	treat	VERB
dti-1297	80	17	ad	ad	NOUN
dti-1297	80	18	,	,	PUNCT
dti-1297	80	19	on	on	ADP
dti-1297	80	20	neurogenesis	neurogenesis	NOUN
dti-1297	80	21	,	,	PUNCT
dti-1297	80	22	will	will	AUX
dti-1297	80	23	be	be	AUX
dti-1297	80	24	a	a	DET
dti-1297	80	25	key	key	ADJ
dti-1297	80	26	factor	factor	NOUN
dti-1297	80	27	.	.	PUNCT
dti-1297	81	1	acknowledgments	acknowledgment	NOUN
dti-1297	81	2	p.t	p.t	PROPN
dti-1297	81	3	.	.	PROPN
dti-1297	81	4	is	be	AUX
dti-1297	81	5	supported	support	VERB
dti-1297	81	6	by	by	ADP
dti-1297	81	7	grants	grant	NOUN
dti-1297	81	8	from	from	ADP
dti-1297	81	9	the	the	DET
dti-1297	81	10	nmrc	nmrc	NOUN
dti-1297	81	11	,	,	PUNCT
dti-1297	81	12	bmrc	bmrc	NOUN
dti-1297	81	13	,	,	PUNCT
dti-1297	81	14	and	and	CCONJ
dti-1297	81	15	the	the	DET
dti-1297	81	16	juvenile	juvenile	ADJ
dti-1297	81	17	diabetes	diabetes	NOUN
dti-1297	81	18	research	research	NOUN
dti-1297	81	19	foundation	foundation	PROPN
dti-1297	81	20	.	.	PUNCT
dti-1297	82	1	references	reference	NOUN
dti-1297	82	2	arrieta	arrieta	PROPN
dti-1297	82	3	,	,	PUNCT
dti-1297	82	4	j.l	j.l	PROPN
dti-1297	82	5	.	.	PROPN
dti-1297	82	6	and	and	CCONJ
dti-1297	82	7	artalejo	artalejo	PROPN
dti-1297	82	8	,	,	PUNCT
dti-1297	82	9	f.r	f.r	PROPN
dti-1297	82	10	.	.	NOUN
dti-1297	82	11	1998	1998	NUM
dti-1297	82	12	.	.	PUNCT
dti-1297	83	1	methodology	methodology	NOUN
dti-1297	83	2	,	,	PUNCT
dti-1297	83	3	results	result	NOUN
dti-1297	83	4	and	and	CCONJ
dti-1297	83	5	quality	quality	NOUN
dti-1297	83	6	of	of	ADP
dti-1297	83	7	clinical	clinical	ADJ
dti-1297	83	8	trials	trial	NOUN
dti-1297	83	9	of	of	ADP
dti-1297	83	10	tacrine	tacrine	NOUN
dti-1297	83	11	in	in	ADP
dti-1297	83	12	the	the	DET
dti-1297	83	13	treatment	treatment	NOUN
dti-1297	83	14	of	of	ADP
dti-1297	83	15	alzheimer	alzheimer	PROPN
dti-1297	83	16	’s	’s	PART
dti-1297	83	17	disease	disease	NOUN
dti-1297	83	18	:	:	PUNCT
dti-1297	83	19	a	a	DET
dti-1297	83	20	systematic	systematic	ADJ
dti-1297	83	21	review	review	NOUN
dti-1297	83	22	of	of	ADP
dti-1297	83	23	the	the	DET
dti-1297	83	24	literature	literature	NOUN
dti-1297	83	25	.	.	PUNCT
dti-1297	84	1	age	age	NOUN
dti-1297	84	2	ageing	ageing	NOUN
dti-1297	84	3	,	,	PUNCT
dti-1297	84	4	27:161–79	27:161–79	PROPN
dti-1297	84	5	.	.	PUNCT
dti-1297	85	1	cameron	cameron	PROPN
dti-1297	85	2	,	,	PUNCT
dti-1297	85	3	h.a	h.a	PROPN
dti-1297	85	4	.	.	PROPN
dti-1297	85	5	,	,	PUNCT
dti-1297	85	6	mcewen	mcewen	PROPN
dti-1297	85	7	,	,	PUNCT
dti-1297	85	8	b.s	b.s	PROPN
dti-1297	85	9	.	.	PROPN
dti-1297	85	10	and	and	CCONJ
dti-1297	85	11	gould	gould	PROPN
dti-1297	85	12	,	,	PUNCT
dti-1297	85	13	e.	e.	PROPN
dti-1297	85	14	1995	1995	NUM
dti-1297	85	15	.	.	PUNCT
dti-1297	86	1	regulation	regulation	NOUN
dti-1297	86	2	of	of	ADP
dti-1297	86	3	adult	adult	NOUN
dti-1297	86	4	neurogenesis	neurogenesis	NOUN
dti-1297	86	5	by	by	ADP
dti-1297	86	6	excitatory	excitatory	ADJ
dti-1297	86	7	input	input	NOUN
dti-1297	86	8	and	and	CCONJ
dti-1297	86	9	nmda	nmda	ADJ
dti-1297	86	10	receptor	receptor	NOUN
dti-1297	86	11	activation	activation	NOUN
dti-1297	86	12	in	in	ADP
dti-1297	86	13	the	the	DET
dti-1297	86	14	dentate	dentate	ADJ
dti-1297	86	15	gyrus	gyrus	NOUN
dti-1297	86	16	.	.	PUNCT
dti-1297	87	1	j.	j.	PROPN
dti-1297	87	2	neurosci	neurosci	PROPN
dti-1297	87	3	.	.	PROPN
dti-1297	87	4	,	,	PUNCT
dti-1297	87	5	15:4687–92	15:4687–92	PROPN
dti-1297	87	6	.	.	PUNCT
dti-1297	88	1	cameron	cameron	PROPN
dti-1297	88	2	.	.	PUNCT
dti-1297	89	1	h.a	h.a	PROPN
dti-1297	89	2	.	.	PROPN
dti-1297	89	3	,	,	PUNCT
dti-1297	89	4	tanapat	tanapat	PROPN
dti-1297	89	5	,	,	PUNCT
dti-1297	89	6	p.	p.	NOUN
dti-1297	89	7	and	and	CCONJ
dti-1297	89	8	gould	gould	PROPN
dti-1297	89	9	,	,	PUNCT
dti-1297	89	10	e.	e.	PROPN
dti-1297	89	11	1998	1998	NUM
dti-1297	89	12	.	.	PUNCT
dti-1297	90	1	adrenal	adrenal	ADJ
dti-1297	90	2	steroids	steroid	NOUN
dti-1297	90	3	and	and	CCONJ
dti-1297	90	4	nmethyl	nmethyl	PROPN
dti-1297	90	5	-	-	PUNCT
dti-1297	90	6	d	d	NOUN
dti-1297	90	7	-	-	PUNCT
dti-1297	90	8	aspartate	aspartate	ADJ
dti-1297	90	9	receptor	receptor	NOUN
dti-1297	90	10	activation	activation	NOUN
dti-1297	90	11	regulate	regulate	VERB
dti-1297	90	12	neurogenesis	neurogenesis	NOUN
dti-1297	90	13	in	in	ADP
dti-1297	90	14	the	the	DET
dti-1297	90	15	dentate	dentate	ADJ
dti-1297	90	16	gyrus	gyrus	NOUN
dti-1297	90	17	of	of	ADP
dti-1297	90	18	adult	adult	NOUN
dti-1297	90	19	rats	rat	NOUN
dti-1297	90	20	through	through	ADP
dti-1297	90	21	a	a	DET
dti-1297	90	22	common	common	ADJ
dti-1297	90	23	pathway	pathway	NOUN
dti-1297	90	24	.	.	PUNCT
dti-1297	91	1	neurosci	neurosci	PROPN
dti-1297	91	2	.	.	PUNCT
dti-1297	91	3	,	,	PUNCT
dti-1297	91	4	82:349–54	82:349–54	NUM
dti-1297	91	5	.	.	PUNCT
dti-1297	92	1	cooper	cooper	PROPN
dti-1297	92	2	-	-	PUNCT
dti-1297	92	3	kuhn	kuhn	PROPN
dti-1297	92	4	,	,	PUNCT
dti-1297	92	5	c.m	c.m	PROPN
dti-1297	92	6	.	.	PROPN
dti-1297	92	7	,	,	PUNCT
dti-1297	92	8	winkler	winkler	PROPN
dti-1297	92	9	,	,	PUNCT
dti-1297	92	10	j.	j.	PROPN
dti-1297	92	11	and	and	CCONJ
dti-1297	92	12	kuhn	kuhn	PROPN
dti-1297	92	13	,	,	PUNCT
dti-1297	92	14	h.g	h.g	PROPN
dti-1297	92	15	.	.	PROPN
dti-1297	92	16	2004	2004	NUM
dti-1297	92	17	.	.	PUNCT
dti-1297	93	1	decreased	decrease	VERB
dti-1297	93	2	neurogenesis	neurogenesis	NOUN
dti-1297	93	3	after	after	ADP
dti-1297	93	4	cholinergic	cholinergic	ADJ
dti-1297	93	5	forebrain	forebrain	NOUN
dti-1297	93	6	lesion	lesion	NOUN
dti-1297	93	7	in	in	ADP
dti-1297	93	8	the	the	DET
dti-1297	93	9	adult	adult	NOUN
dti-1297	93	10	rat	rat	NOUN
dti-1297	93	11	.	.	PROPN
dti-1297	93	12	j.	j.	PROPN
dti-1297	93	13	neurosci	neurosci	PROPN
dti-1297	93	14	.	.	PUNCT
dti-1297	94	1	res	re	NOUN
dti-1297	94	2	.	.	PROPN
dti-1297	94	3	,	,	PUNCT
dti-1297	94	4	77:155–65	77:155–65	PROPN
dti-1297	94	5	.	.	PUNCT
dti-1297	95	1	dodart	dodart	PROPN
dti-1297	95	2	,	,	PUNCT
dti-1297	95	3	j.c	j.c	PROPN
dti-1297	95	4	.	.	PROPN
dti-1297	95	5	,	,	PUNCT
dti-1297	95	6	mathis	mathis	PROPN
dti-1297	95	7	,	,	PUNCT
dti-1297	95	8	c.	c.	PROPN
dti-1297	95	9	and	and	CCONJ
dti-1297	95	10	bales	bale	NOUN
dti-1297	95	11	,	,	PUNCT
dti-1297	95	12	k.r	k.r	PROPN
dti-1297	95	13	.	.	PROPN
dti-1297	95	14	et	et	PROPN
dti-1297	95	15	al	al	PROPN
dti-1297	95	16	.	.	PROPN
dti-1297	95	17	2002	2002	NUM
dti-1297	95	18	.	.	PUNCT
dti-1297	96	1	does	do	AUX
dti-1297	96	2	my	my	PRON
dti-1297	96	3	mouse	mouse	PROPN
dti-1297	96	4	have	have	VERB
dti-1297	96	5	alzheimer	alzheimer	PROPN
dti-1297	96	6	’s	’s	PART
dti-1297	96	7	disease	disease	NOUN
dti-1297	96	8	?	?	PUNCT
dti-1297	97	1	genes	gene	NOUN
dti-1297	97	2	brain	brain	NOUN
dti-1297	97	3	behav	behav	NOUN
dti-1297	97	4	.	.	PUNCT
dti-1297	97	5	,	,	PUNCT
dti-1297	98	1	1:142–55	1:142–55	X
dti-1297	98	2	.	.	PUNCT
dti-1297	99	1	feng	feng	PROPN
dti-1297	99	2	,	,	PUNCT
dti-1297	99	3	r.	r.	PROPN
dti-1297	99	4	,	,	PUNCT
dti-1297	99	5	rampon	rampon	PROPN
dti-1297	99	6	,	,	PUNCT
dti-1297	99	7	c.	c.	PROPN
dti-1297	99	8	and	and	CCONJ
dti-1297	99	9	tang	tang	PROPN
dti-1297	99	10	,	,	PUNCT
dti-1297	99	11	y.p	y.p	PROPN
dti-1297	99	12	.	.	PROPN
dti-1297	99	13	et	et	PROPN
dti-1297	99	14	al	al	PROPN
dti-1297	99	15	.	.	PROPN
dti-1297	99	16	2001	2001	NUM
dti-1297	99	17	.	.	PUNCT
dti-1297	100	1	defi	defi	PROPN
dti-1297	100	2	cient	cient	PROPN
dti-1297	100	3	neurogenesis	neurogenesis	NOUN
dti-1297	100	4	in	in	ADP
dti-1297	100	5	forebrain	forebrain	NOUN
dti-1297	100	6	-	-	PUNCT
dti-1297	100	7	specifi	specifi	NOUN
dti-1297	100	8	c	c	PROPN
dti-1297	100	9	presenilin-1	presenilin-1	NUM
dti-1297	100	10	knockout	knockout	NOUN
dti-1297	100	11	mice	mouse	NOUN
dti-1297	100	12	is	be	AUX
dti-1297	100	13	associated	associate	VERB
dti-1297	100	14	with	with	ADP
dti-1297	100	15	reduced	reduced	ADJ
dti-1297	100	16	clearance	clearance	NOUN
dti-1297	100	17	of	of	ADP
dti-1297	100	18	hippocampal	hippocampal	ADJ
dti-1297	100	19	memory	memory	NOUN
dti-1297	100	20	traces	trace	NOUN
dti-1297	100	21	.	.	PUNCT
dti-1297	101	1	neuron	neuron	PROPN
dti-1297	101	2	,	,	PUNCT
dti-1297	101	3	32:911–26	32:911–26	NOUN
dti-1297	101	4	.	.	PUNCT
dti-1297	102	1	erratum	erratum	PROPN
dti-1297	102	2	in	in	ADP
dti-1297	102	3	:	:	PUNCT
dti-1297	102	4	2002	2002	NUM
dti-1297	102	5	.	.	PUNCT
dti-1297	103	1	neuron	neuron	PROPN
dti-1297	103	2	,	,	PUNCT
dti-1297	103	3	33:313	33:313	NUM
dti-1297	103	4	.	.	PUNCT
dti-1297	104	1	fujiwara	fujiwara	PROPN
dti-1297	104	2	,	,	PUNCT
dti-1297	104	3	y.	y.	PROPN
dti-1297	104	4	,	,	PUNCT
dti-1297	104	5	tanaka	tanaka	PROPN
dti-1297	104	6	,	,	PUNCT
dti-1297	104	7	n.	n.	PROPN
dti-1297	104	8	and	and	CCONJ
dti-1297	104	9	ishida	ishida	PROPN
dti-1297	104	10	,	,	PUNCT
dti-1297	104	11	o.	o.	PROPN
dti-1297	104	12	et	et	PROPN
dti-1297	104	13	al	al	PROPN
dti-1297	104	14	.	.	PROPN
dti-1297	104	15	2004	2004	NUM
dti-1297	104	16	.	.	PUNCT
dti-1297	105	1	intravenously	intravenously	ADV
dti-1297	105	2	injected	inject	VERB
dti-1297	105	3	neural	neural	ADJ
dti-1297	105	4	progenitor	progenitor	NOUN
dti-1297	105	5	cells	cell	NOUN
dti-1297	105	6	of	of	ADP
dti-1297	105	7	transgenic	transgenic	NOUN
dti-1297	105	8	rats	rat	NOUN
dti-1297	105	9	can	can	AUX
dti-1297	105	10	migrate	migrate	VERB
dti-1297	105	11	to	to	ADP
dti-1297	105	12	the	the	DET
dti-1297	105	13	injured	injure	VERB
dti-1297	105	14	spinal	spinal	NOUN
dti-1297	105	15	cord	cord	NOUN
dti-1297	105	16	and	and	CCONJ
dti-1297	105	17	differentiate	differentiate	VERB
dti-1297	105	18	into	into	ADP
dti-1297	105	19	neurons	neuron	NOUN
dti-1297	105	20	,	,	PUNCT
dti-1297	105	21	astrocytes	astrocyte	NOUN
dti-1297	105	22	and	and	CCONJ
dti-1297	105	23	oligodendrocytes	oligodendrocyte	NOUN
dti-1297	105	24	.	.	PUNCT
dti-1297	106	1	neurosci	neurosci	PROPN
dti-1297	106	2	.	.	PUNCT
dti-1297	107	1	lett	lett	PROPN
dti-1297	107	2	.	.	PROPN
dti-1297	107	3	,	,	PUNCT
dti-1297	108	1	366:287–91	366:287–91	NUM
dti-1297	108	2	.	.	PUNCT
dti-1297	108	3	gage	gage	PROPN
dti-1297	108	4	,	,	PUNCT
dti-1297	108	5	f.h	f.h	PROPN
dti-1297	108	6	.	.	PROPN
dti-1297	108	7	,	,	PUNCT
dti-1297	108	8	coates	coates	PROPN
dti-1297	108	9	,	,	PUNCT
dti-1297	108	10	p.w	p.w	PROPN
dti-1297	108	11	.	.	PROPN
dti-1297	108	12	and	and	CCONJ
dti-1297	108	13	palmer	palmer	PROPN
dti-1297	108	14	,	,	PUNCT
dti-1297	108	15	t.d	t.d	PROPN
dti-1297	108	16	.	.	PROPN
dti-1297	108	17	et	et	PROPN
dti-1297	108	18	al	al	PROPN
dti-1297	108	19	.	.	PROPN
dti-1297	108	20	1995	1995	NUM
dti-1297	108	21	.	.	PUNCT
dti-1297	109	1	survival	survival	NOUN
dti-1297	109	2	and	and	CCONJ
dti-1297	109	3	differentiation	differentiation	NOUN
dti-1297	109	4	of	of	ADP
dti-1297	109	5	adult	adult	NOUN
dti-1297	109	6	neuronal	neuronal	ADJ
dti-1297	109	7	progenitor	progenitor	NOUN
dti-1297	109	8	cells	cell	NOUN
dti-1297	109	9	transplanted	transplant	VERB
dti-1297	109	10	to	to	ADP
dti-1297	109	11	the	the	DET
dti-1297	109	12	adult	adult	NOUN
dti-1297	109	13	brain	brain	NOUN
dti-1297	109	14	.	.	PUNCT
dti-1297	110	1	proc	proc	PROPN
dti-1297	110	2	.	.	PUNCT
dti-1297	111	1	natl	natl	PROPN
dti-1297	111	2	.	.	PUNCT
dti-1297	112	1	acad	acad	PROPN
dti-1297	112	2	.	.	PUNCT
dti-1297	113	1	sci	sci	PROPN
dti-1297	113	2	.	.	PROPN
dti-1297	113	3	,	,	PUNCT
dti-1297	113	4	u.s.a	u.s.a	PROPN
dti-1297	113	5	.	.	PROPN
dti-1297	113	6	,	,	PUNCT
dti-1297	113	7	92:11879–83	92:11879–83	X
dti-1297	113	8	.	.	PUNCT
dti-1297	114	1	gage	gage	PROPN
dti-1297	114	2	,	,	PUNCT
dti-1297	114	3	f.h	f.h	PROPN
dti-1297	114	4	.	.	PROPN
dti-1297	114	5	2000	2000	NUM
dti-1297	114	6	.	.	PUNCT
dti-1297	115	1	mammalian	mammalian	ADJ
dti-1297	115	2	neural	neural	ADJ
dti-1297	115	3	stem	stem	NOUN
dti-1297	115	4	cells	cell	NOUN
dti-1297	115	5	.	.	PUNCT
dti-1297	116	1	science	science	NOUN
dti-1297	116	2	,	,	PUNCT
dti-1297	116	3	287:1433–8	287:1433–8	NUM
dti-1297	116	4	.	.	PUNCT
dti-1297	117	1	german	german	PROPN
dti-1297	117	2	,	,	PUNCT
dti-1297	117	3	d.c	d.c	PROPN
dti-1297	117	4	.	.	PROPN
dti-1297	118	1	and	and	CCONJ
dti-1297	118	2	eisch	eisch	PROPN
dti-1297	118	3	,	,	PUNCT
dti-1297	118	4	a.j	a.j	PROPN
dti-1297	118	5	.	.	PROPN
dti-1297	118	6	2004	2004	NUM
dti-1297	118	7	.	.	PUNCT
dti-1297	119	1	mouse	mouse	NOUN
dti-1297	119	2	models	model	NOUN
dti-1297	119	3	of	of	ADP
dti-1297	119	4	alzheimer	alzheimer	PROPN
dti-1297	119	5	’s	’s	PART
dti-1297	119	6	disease	disease	NOUN
dti-1297	119	7	:	:	PUNCT
dti-1297	119	8	insight	insight	NOUN
dti-1297	119	9	into	into	ADP
dti-1297	119	10	treatment	treatment	NOUN
dti-1297	119	11	.	.	PUNCT
dti-1297	120	1	rev	rev	PROPN
dti-1297	120	2	.	.	PROPN
dti-1297	120	3	neurosci	neurosci	PROPN
dti-1297	120	4	.	.	PUNCT
dti-1297	120	5	,	,	PUNCT
dti-1297	120	6	15:353–69	15:353–69	PROPN
dti-1297	120	7	.	.	PUNCT
dti-1297	121	1	gould	gould	PROPN
dti-1297	121	2	,	,	PUNCT
dti-1297	121	3	e.	e.	PROPN
dti-1297	121	4	,	,	PUNCT
dti-1297	121	5	mcewen	mcewen	PROPN
dti-1297	121	6	,	,	PUNCT
dti-1297	121	7	b.s	b.s	PROPN
dti-1297	121	8	.	.	PROPN
dti-1297	121	9	and	and	CCONJ
dti-1297	121	10	tanapat	tanapat	PROPN
dti-1297	121	11	,	,	PUNCT
dti-1297	121	12	p.	p.	NOUN
dti-1297	121	13	et	et	NOUN
dti-1297	122	1	al	al	PROPN
dti-1297	122	2	.	.	PROPN
dti-1297	122	3	1997	1997	NUM
dti-1297	122	4	.	.	PUNCT
dti-1297	123	1	neurogenesis	neurogenesis	NOUN
dti-1297	123	2	in	in	ADP
dti-1297	123	3	the	the	DET
dti-1297	123	4	dentate	dentate	ADJ
dti-1297	123	5	gyrus	gyrus	NOUN
dti-1297	123	6	of	of	ADP
dti-1297	123	7	the	the	DET
dti-1297	123	8	adult	adult	NOUN
dti-1297	123	9	tree	tree	NOUN
dti-1297	123	10	shrew	shrew	NOUN
dti-1297	123	11	is	be	AUX
dti-1297	123	12	regulated	regulate	VERB
dti-1297	123	13	by	by	ADP
dti-1297	123	14	psychosocial	psychosocial	ADJ
dti-1297	123	15	stress	stress	NOUN
dti-1297	123	16	and	and	CCONJ
dti-1297	123	17	nmda	nmda	ADJ
dti-1297	123	18	receptor	receptor	NOUN
dti-1297	123	19	activation	activation	NOUN
dti-1297	123	20	.	.	PUNCT
dti-1297	124	1	j.	j.	PROPN
dti-1297	124	2	neurosci	neurosci	PROPN
dti-1297	124	3	.	.	PROPN
dti-1297	124	4	,	,	PUNCT
dti-1297	124	5	17:2492–8	17:2492–8	X
dti-1297	124	6	.	.	PUNCT
dti-1297	125	1	hardy	hardy	ADJ
dti-1297	125	2	,	,	PUNCT
dti-1297	125	3	j.	j.	PROPN
dti-1297	125	4	and	and	CCONJ
dti-1297	125	5	selkoe	selkoe	PROPN
dti-1297	125	6	,	,	PUNCT
dti-1297	125	7	d.j	d.j	PROPN
dti-1297	125	8	.	.	PROPN
dti-1297	125	9	2002	2002	NUM
dti-1297	125	10	.	.	PUNCT
dti-1297	126	1	the	the	DET
dti-1297	126	2	amyloid	amyloid	NOUN
dti-1297	126	3	hypothesis	hypothesis	NOUN
dti-1297	126	4	of	of	ADP
dti-1297	126	5	alzheimer	alzheimer	PROPN
dti-1297	126	6	’s	’s	PART
dti-1297	126	7	disease	disease	NOUN
dti-1297	126	8	:	:	PUNCT
dti-1297	126	9	progress	progress	NOUN
dti-1297	126	10	and	and	CCONJ
dti-1297	126	11	problems	problem	NOUN
dti-1297	126	12	on	on	ADP
dti-1297	126	13	the	the	DET
dti-1297	126	14	road	road	NOUN
dti-1297	126	15	to	to	ADP
dti-1297	126	16	therapeutics	therapeutic	NOUN
dti-1297	126	17	.	.	PUNCT
dti-1297	127	1	science	science	NOUN
dti-1297	127	2	,	,	PUNCT
dti-1297	127	3	297:353–6	297:353–6	NUM
dti-1297	127	4	.	.	PUNCT
dti-1297	127	5	erratum	erratum	PROPN
dti-1297	127	6	in	in	ADP
dti-1297	127	7	:	:	PUNCT
dti-1297	127	8	2002	2002	NUM
dti-1297	127	9	.	.	PUNCT
dti-1297	128	1	science	science	NOUN
dti-1297	128	2	,	,	PUNCT
dti-1297	128	3	297:2209	297:2209	PROPN
dti-1297	128	4	.	.	PUNCT
dti-1297	128	5	herrup	herrup	NOUN
dti-1297	128	6	,	,	PUNCT
dti-1297	128	7	k.	k.	PROPN
dti-1297	128	8	,	,	PUNCT
dti-1297	128	9	neve	neve	PROPN
dti-1297	128	10	,	,	PUNCT
dti-1297	128	11	r.	r.	PROPN
dti-1297	128	12	and	and	CCONJ
dti-1297	128	13	ackerman	ackerman	PROPN
dti-1297	128	14	,	,	PUNCT
dti-1297	128	15	s.l	s.l	PROPN
dti-1297	128	16	.	.	PROPN
dti-1297	128	17	et	et	PROPN
dti-1297	128	18	al	al	PROPN
dti-1297	128	19	.	.	PROPN
dti-1297	128	20	2004	2004	NUM
dti-1297	128	21	.	.	PUNCT
dti-1297	129	1	divide	divide	VERB
dti-1297	129	2	and	and	CCONJ
dti-1297	129	3	die	die	VERB
dti-1297	129	4	:	:	PUNCT
dti-1297	129	5	cell	cell	NOUN
dti-1297	129	6	cycle	cycle	NOUN
dti-1297	129	7	events	event	NOUN
dti-1297	129	8	as	as	ADP
dti-1297	129	9	triggers	trigger	NOUN
dti-1297	129	10	of	of	ADP
dti-1297	129	11	nerve	nerve	NOUN
dti-1297	129	12	cell	cell	NOUN
dti-1297	129	13	death	death	NOUN
dti-1297	129	14	.	.	PUNCT
dti-1297	130	1	j.	j.	PROPN
dti-1297	130	2	neurosci	neurosci	PROPN
dti-1297	130	3	.	.	PROPN
dti-1297	130	4	,	,	PUNCT
dti-1297	130	5	24:9232–9	24:9232–9	NUM
dti-1297	130	6	.	.	NUM
dti-1297	130	7	ikonomidou	ikonomidou	PROPN
dti-1297	130	8	,	,	PUNCT
dti-1297	130	9	c.	c.	PROPN
dti-1297	130	10	,	,	PUNCT
dti-1297	130	11	bosch	bosch	PROPN
dti-1297	130	12	,	,	PUNCT
dti-1297	130	13	f.	f.	PROPN
dti-1297	130	14	and	and	CCONJ
dti-1297	130	15	miksa	miksa	PROPN
dti-1297	130	16	,	,	PUNCT
dti-1297	130	17	m.	m.	NOUN
dti-1297	130	18	et	et	PROPN
dti-1297	130	19	al	al	PROPN
dti-1297	130	20	.	.	PROPN
dti-1297	130	21	1999	1999	NUM
dti-1297	130	22	.	.	PUNCT
dti-1297	131	1	blockade	blockade	NOUN
dti-1297	131	2	of	of	ADP
dti-1297	131	3	nmda	nmda	ADJ
dti-1297	131	4	receptors	receptor	NOUN
dti-1297	131	5	and	and	CCONJ
dti-1297	131	6	apoptotic	apoptotic	ADJ
dti-1297	131	7	neurodegeneration	neurodegeneration	NOUN
dti-1297	131	8	in	in	ADP
dti-1297	131	9	the	the	DET
dti-1297	131	10	developing	develop	VERB
dti-1297	131	11	brain	brain	NOUN
dti-1297	131	12	.	.	PUNCT
dti-1297	132	1	science	science	NOUN
dti-1297	132	2	,	,	PUNCT
dti-1297	132	3	283:70–4	283:70–4	NUM
dti-1297	132	4	.	.	PUNCT
dti-1297	133	1	jin	jin	PROPN
dti-1297	133	2	,	,	PUNCT
dti-1297	133	3	k.	k.	PROPN
dti-1297	133	4	,	,	PUNCT
dti-1297	133	5	peel	peel	NOUN
dti-1297	133	6	,	,	PUNCT
dti-1297	133	7	a.l	a.l	PROPN
dti-1297	133	8	.	.	PROPN
dti-1297	133	9	and	and	CCONJ
dti-1297	133	10	mao	mao	PROPN
dti-1297	133	11	,	,	PUNCT
dti-1297	133	12	x.o	x.o	PROPN
dti-1297	133	13	.	.	PROPN
dti-1297	133	14	et	et	PROPN
dti-1297	133	15	al	al	PROPN
dti-1297	133	16	.	.	PROPN
dti-1297	133	17	2004a	2004a	NUM
dti-1297	133	18	.	.	PUNCT
dti-1297	134	1	increased	increase	VERB
dti-1297	134	2	hippocampal	hippocampal	ADJ
dti-1297	134	3	neurogenesis	neurogenesis	NOUN
dti-1297	134	4	in	in	ADP
dti-1297	134	5	alzheimer	alzheimer	PROPN
dti-1297	134	6	’s	’s	PART
dti-1297	134	7	disease	disease	NOUN
dti-1297	134	8	.	.	PUNCT
dti-1297	135	1	proc	proc	PROPN
dti-1297	135	2	.	.	PUNCT
dti-1297	136	1	natl	natl	PROPN
dti-1297	136	2	.	.	PUNCT
dti-1297	137	1	acad	acad	PROPN
dti-1297	137	2	.	.	PUNCT
dti-1297	138	1	sci	sci	PROPN
dti-1297	138	2	.	.	PROPN
dti-1297	138	3	,	,	PUNCT
dti-1297	138	4	u.s.a	u.s.a	PROPN
dti-1297	138	5	.	.	PROPN
dti-1297	138	6	,	,	PUNCT
dti-1297	138	7	101:343–7	101:343–7	NUM
dti-1297	138	8	.	.	PUNCT
dti-1297	139	1	jin	jin	PROPN
dti-1297	139	2	,	,	PUNCT
dti-1297	139	3	k.	k.	PROPN
dti-1297	139	4	,	,	PUNCT
dti-1297	139	5	galvan	galvan	PROPN
dti-1297	139	6	,	,	PUNCT
dti-1297	139	7	v.	v.	PROPN
dti-1297	139	8	and	and	CCONJ
dti-1297	139	9	xie	xie	PROPN
dti-1297	139	10	,	,	PUNCT
dti-1297	139	11	l.	l.	PROPN
dti-1297	139	12	et	et	PROPN
dti-1297	139	13	al	al	PROPN
dti-1297	139	14	.	.	PROPN
dti-1297	139	15	2004b	2004b	PROPN
dti-1297	139	16	.	.	PUNCT
dti-1297	140	1	enhanced	enhance	VERB
dti-1297	140	2	neurogenesis	neurogenesis	NOUN
dti-1297	140	3	in	in	ADP
dti-1297	140	4	alzheimer	alzheimer	PROPN
dti-1297	140	5	’s	’s	PART
dti-1297	140	6	disease	disease	NOUN
dti-1297	140	7	transgenic	transgenic	NOUN
dti-1297	140	8	(	(	PUNCT
dti-1297	140	9	pdgf	pdgf	NOUN
dti-1297	140	10	-	-	PUNCT
dti-1297	140	11	appsw	appsw	NOUN
dti-1297	140	12	,	,	PUNCT
dti-1297	140	13	ind	ind	ADJ
dti-1297	140	14	)	)	PUNCT
dti-1297	140	15	mice	mouse	NOUN
dti-1297	140	16	.	.	PUNCT
dti-1297	141	1	proc	proc	NOUN
dti-1297	141	2	.	.	PUNCT
dti-1297	142	1	natl	natl	PROPN
dti-1297	142	2	.	.	PUNCT
dti-1297	143	1	acad	acad	PROPN
dti-1297	143	2	.	.	PUNCT
dti-1297	144	1	sci	sci	PROPN
dti-1297	144	2	.	.	PROPN
dti-1297	144	3	,	,	PUNCT
dti-1297	144	4	u.s.a	u.s.a	PROPN
dti-1297	144	5	.	.	PROPN
dti-1297	144	6	,	,	PUNCT
dti-1297	144	7	101:13363–7	101:13363–7	NUM
dti-1297	144	8	.	.	PUNCT
dti-1297	144	9	drug	drug	NOUN
dti-1297	144	10	target	target	NOUN
dti-1297	144	11	insights	insight	NOUN
dti-1297	144	12	2006	2006	NUM
dti-1297	144	13	:	:	PUNCT
dti-1297	144	14	14	14	NUM
dti-1297	144	15	philippe	philippe	PROPN
dti-1297	144	16	taupin	taupin	PROPN
dti-1297	144	17	jin	jin	PROPN
dti-1297	144	18	,	,	PUNCT
dti-1297	144	19	k.	k.	PROPN
dti-1297	144	20	,	,	PUNCT
dti-1297	144	21	xie	xie	PROPN
dti-1297	144	22	,	,	PUNCT
dti-1297	144	23	l.	l.	PROPN
dti-1297	144	24	and	and	CCONJ
dti-1297	144	25	mao	mao	PROPN
dti-1297	144	26	,	,	PUNCT
dti-1297	144	27	x.o	x.o	PROPN
dti-1297	144	28	.	.	PROPN
dti-1297	144	29	et	et	PROPN
dti-1297	144	30	al	al	PROPN
dti-1297	144	31	.	.	PROPN
dti-1297	144	32	2006	2006	NUM
dti-1297	144	33	.	.	PUNCT
dti-1297	145	1	alzheimer	alzheimer	PROPN
dti-1297	145	2	’s	’s	PART
dti-1297	145	3	disease	disease	NOUN
dti-1297	145	4	drugs	drug	NOUN
dti-1297	145	5	promote	promote	VERB
dti-1297	145	6	neurogenesis	neurogenesis	NOUN
dti-1297	145	7	.	.	PUNCT
dti-1297	146	1	brain	brain	NOUN
dti-1297	146	2	res	re	NOUN
dti-1297	146	3	.	.	PUNCT
dti-1297	146	4	,	,	PUNCT
dti-1297	147	1	1085:183–8	1085:183–8	X
dti-1297	147	2	.	.	PUNCT
dti-1297	148	1	macklis	macklis	PROPN
dti-1297	148	2	,	,	PUNCT
dti-1297	148	3	j.d	j.d	PROPN
dti-1297	148	4	.	.	PROPN
dti-1297	148	5	1993	1993	NUM
dti-1297	148	6	.	.	PUNCT
dti-1297	149	1	transplanted	transplant	VERB
dti-1297	149	2	neocortical	neocortical	ADJ
dti-1297	149	3	neurons	neuron	NOUN
dti-1297	149	4	migrate	migrate	VERB
dti-1297	149	5	selectively	selectively	ADV
dti-1297	149	6	into	into	ADP
dti-1297	149	7	regions	region	NOUN
dti-1297	149	8	of	of	ADP
dti-1297	149	9	neuronal	neuronal	ADJ
dti-1297	149	10	degeneration	degeneration	NOUN
dti-1297	149	11	produced	produce	VERB
dti-1297	149	12	by	by	ADP
dti-1297	149	13	chromophoretargeted	chromophoretargete	VERB
dti-1297	149	14	laser	laser	NOUN
dti-1297	149	15	photolysis	photolysis	NOUN
dti-1297	149	16	.	.	PUNCT
dti-1297	150	1	j.	j.	PROPN
dti-1297	150	2	neurosci	neurosci	PROPN
dti-1297	150	3	.	.	PROPN
dti-1297	150	4	,	,	PUNCT
dti-1297	150	5	13:3848–63	13:3848–63	NUM
dti-1297	150	6	.	.	PUNCT
dti-1297	151	1	meshi	meshi	PROPN
dti-1297	151	2	,	,	PUNCT
dti-1297	151	3	d.	d.	PROPN
dti-1297	151	4	,	,	PUNCT
dti-1297	151	5	drew	draw	VERB
dti-1297	151	6	,	,	PUNCT
dti-1297	151	7	m.r	m.r	PROPN
dti-1297	151	8	.	.	PROPN
dti-1297	151	9	and	and	CCONJ
dti-1297	151	10	saxe	saxe	PROPN
dti-1297	151	11	,	,	PUNCT
dti-1297	151	12	m.	m.	NOUN
dti-1297	151	13	et	et	PROPN
dti-1297	151	14	al	al	PROPN
dti-1297	151	15	.	.	PROPN
dti-1297	151	16	2006	2006	NUM
dti-1297	151	17	.	.	PUNCT
dti-1297	152	1	hippocampal	hippocampal	ADJ
dti-1297	152	2	neurogenesis	neurogenesis	NOUN
dti-1297	152	3	is	be	AUX
dti-1297	152	4	not	not	PART
dti-1297	152	5	required	require	VERB
dti-1297	152	6	for	for	ADP
dti-1297	152	7	behavioral	behavioral	ADJ
dti-1297	152	8	effects	effect	NOUN
dti-1297	152	9	of	of	ADP
dti-1297	152	10	environmental	environmental	ADJ
dti-1297	152	11	enrichment	enrichment	NOUN
dti-1297	152	12	.	.	PUNCT
dti-1297	153	1	nat	nat	PROPN
dti-1297	153	2	.	.	PUNCT
dti-1297	154	1	neurosci	neurosci	PROPN
dti-1297	154	2	.	.	PUNCT
dti-1297	154	3	,	,	PUNCT
dti-1297	155	1	9:729–31	9:729–31	PROPN
dti-1297	155	2	.	.	PUNCT
dti-1297	155	3	mcshane	mcshane	PROPN
dti-1297	155	4	,	,	PUNCT
dti-1297	155	5	r.	r.	PROPN
dti-1297	155	6	,	,	PUNCT
dti-1297	155	7	areosa	areosa	NOUN
dti-1297	155	8	sastre	sastre	NOUN
dti-1297	155	9	,	,	PUNCT
dti-1297	155	10	a.	a.	NOUN
dti-1297	155	11	and	and	CCONJ
dti-1297	155	12	minakaran	minakaran	VERB
dti-1297	155	13	,	,	PUNCT
dti-1297	155	14	n.	n.	PROPN
dti-1297	155	15	2006	2006	NUM
dti-1297	155	16	.	.	PUNCT
dti-1297	156	1	memantine	memantine	VERB
dti-1297	156	2	for	for	ADP
dti-1297	156	3	dementia	dementia	NOUN
dti-1297	156	4	.	.	PUNCT
dti-1297	157	1	cochrane	cochrane	NOUN
dti-1297	157	2	database	database	PROPN
dti-1297	157	3	syst	syst	PROPN
dti-1297	157	4	.	.	PUNCT
dti-1297	158	1	rev	rev	PROPN
dti-1297	158	2	.	.	PROPN
dti-1297	158	3	,	,	PUNCT
dti-1297	158	4	2	2	NUM
dti-1297	158	5	:	:	PUNCT
dti-1297	158	6	cd003154	cd003154	NOUN
dti-1297	158	7	.	.	PUNCT
dti-1297	159	1	miller	miller	PROPN
dti-1297	159	2	,	,	PUNCT
dti-1297	159	3	m.w	m.w	PROPN
dti-1297	159	4	.	.	PROPN
dti-1297	159	5	,	,	PUNCT
dti-1297	159	6	nowakowski	nowakowski	PROPN
dti-1297	159	7	,	,	PUNCT
dti-1297	159	8	r.s	r.s	PROPN
dti-1297	159	9	.	.	PROPN
dti-1297	159	10	1988	1988	NUM
dti-1297	159	11	.	.	PUNCT
dti-1297	160	1	use	use	NOUN
dti-1297	160	2	of	of	ADP
dti-1297	160	3	bromodeoxyuridine	bromodeoxyuridine	NOUN
dti-1297	160	4	-	-	PUNCT
dti-1297	160	5	immunohistochemistry	immunohistochemistry	NOUN
dti-1297	160	6	to	to	PART
dti-1297	160	7	examine	examine	VERB
dti-1297	160	8	the	the	DET
dti-1297	160	9	proliferation	proliferation	NOUN
dti-1297	160	10	,	,	PUNCT
dti-1297	160	11	migration	migration	NOUN
dti-1297	160	12	and	and	CCONJ
dti-1297	160	13	time	time	NOUN
dti-1297	160	14	of	of	ADP
dti-1297	160	15	origin	origin	NOUN
dti-1297	160	16	of	of	ADP
dti-1297	160	17	cells	cell	NOUN
dti-1297	160	18	in	in	ADP
dti-1297	160	19	the	the	DET
dti-1297	160	20	central	central	ADJ
dti-1297	160	21	nervous	nervous	ADJ
dti-1297	160	22	system	system	NOUN
dti-1297	160	23	.	.	PUNCT
dti-1297	161	1	brain	brain	NOUN
dti-1297	161	2	res	re	NOUN
dti-1297	161	3	.	.	PUNCT
dti-1297	161	4	,	,	PUNCT
dti-1297	161	5	457:44–52	457:44–52	X
dti-1297	161	6	.	.	PUNCT
dti-1297	161	7	mohapel	mohapel	PROPN
dti-1297	161	8	,	,	PUNCT
dti-1297	161	9	p.	p.	NOUN
dti-1297	161	10	,	,	PUNCT
dti-1297	161	11	leanza	leanza	NOUN
dti-1297	161	12	,	,	PUNCT
dti-1297	161	13	g.	g.	PROPN
dti-1297	161	14	and	and	CCONJ
dti-1297	161	15	kokaia	kokaia	PROPN
dti-1297	161	16	,	,	PUNCT
dti-1297	161	17	m.	m.	NOUN
dti-1297	161	18	et	et	PROPN
dti-1297	161	19	al	al	PROPN
dti-1297	161	20	.	.	PROPN
dti-1297	161	21	2005	2005	NUM
dti-1297	161	22	.	.	PUNCT
dti-1297	162	1	forebrain	forebrain	NOUN
dti-1297	162	2	acetylcholine	acetylcholine	NOUN
dti-1297	162	3	regulates	regulate	VERB
dti-1297	162	4	adult	adult	NOUN
dti-1297	162	5	hippocampal	hippocampal	ADJ
dti-1297	162	6	neurogenesis	neurogenesis	NOUN
dti-1297	162	7	and	and	CCONJ
dti-1297	162	8	learning	learning	NOUN
dti-1297	162	9	.	.	PUNCT
dti-1297	163	1	neurobiol	neurobiol	NOUN
dti-1297	163	2	.	.	PUNCT
dti-1297	164	1	aging	aging	NOUN
dti-1297	164	2	,	,	PUNCT
dti-1297	164	3	26:939–46	26:939–46	PROPN
dti-1297	164	4	.	.	PUNCT
dti-1297	165	1	nacher	nacher	PROPN
dti-1297	165	2	,	,	PUNCT
dti-1297	165	3	j.	j.	PROPN
dti-1297	165	4	,	,	PUNCT
dti-1297	165	5	rosell	rosell	PROPN
dti-1297	165	6	,	,	PUNCT
dti-1297	165	7	d.r	d.r	PROPN
dti-1297	165	8	.	.	PROPN
dti-1297	165	9	and	and	CCONJ
dti-1297	165	10	alonso	alonso	PROPN
dti-1297	165	11	-	-	PUNCT
dti-1297	165	12	llosa	llosa	PROPN
dti-1297	165	13	,	,	PUNCT
dti-1297	165	14	g.	g.	PROPN
dti-1297	165	15	et	et	PROPN
dti-1297	166	1	al	al	PROPN
dti-1297	166	2	.	.	PROPN
dti-1297	166	3	2001	2001	NUM
dti-1297	166	4	.	.	PUNCT
dti-1297	167	1	nmda	nmda	ADJ
dti-1297	167	2	receptor	receptor	NOUN
dti-1297	167	3	antagonist	antagonist	NOUN
dti-1297	167	4	treatment	treatment	NOUN
dti-1297	167	5	induces	induce	VERB
dti-1297	167	6	a	a	DET
dti-1297	167	7	long	long	ADV
dti-1297	167	8	-	-	PUNCT
dti-1297	167	9	lasting	last	VERB
dti-1297	167	10	increase	increase	NOUN
dti-1297	167	11	in	in	ADP
dti-1297	167	12	the	the	DET
dti-1297	167	13	number	number	NOUN
dti-1297	167	14	of	of	ADP
dti-1297	167	15	proliferating	proliferate	VERB
dti-1297	167	16	cells	cell	NOUN
dti-1297	167	17	,	,	PUNCT
dti-1297	167	18	psa	psa	NOUN
dti-1297	167	19	-	-	PUNCT
dti-1297	167	20	ncam	ncam	NOUN
dti-1297	167	21	-	-	PUNCT
dti-1297	167	22	immunoreactive	immunoreactive	ADJ
dti-1297	167	23	granule	granule	NOUN
dti-1297	167	24	neurons	neuron	NOUN
dti-1297	167	25	and	and	CCONJ
dti-1297	167	26	radial	radial	ADJ
dti-1297	167	27	glia	glia	NOUN
dti-1297	167	28	in	in	ADP
dti-1297	167	29	the	the	DET
dti-1297	167	30	adult	adult	NOUN
dti-1297	167	31	rat	rat	NOUN
dti-1297	167	32	dentate	dentate	NOUN
dti-1297	167	33	gyrus	gyru	NOUN
dti-1297	167	34	.	.	PUNCT
dti-1297	168	1	eur	eur	PROPN
dti-1297	168	2	.	.	PUNCT
dti-1297	169	1	j.	j.	PROPN
dti-1297	169	2	neurosci	neurosci	PROPN
dti-1297	169	3	.	.	PROPN
dti-1297	169	4	,	,	PUNCT
dti-1297	169	5	13:512–20	13:512–20	PROPN
dti-1297	169	6	.	.	PUNCT
dti-1297	170	1	nacher	nacher	PROPN
dti-1297	170	2	,	,	PUNCT
dti-1297	170	3	j.	j.	PROPN
dti-1297	170	4	,	,	PUNCT
dti-1297	170	5	alonso	alonso	PROPN
dti-1297	170	6	-	-	PUNCT
dti-1297	170	7	llosa	llosa	PROPN
dti-1297	170	8	,	,	PUNCT
dti-1297	170	9	g.	g.	PROPN
dti-1297	170	10	and	and	CCONJ
dti-1297	170	11	rosell	rosell	VERB
dti-1297	170	12	,	,	PUNCT
dti-1297	170	13	d.r	d.r	PROPN
dti-1297	170	14	.	.	PROPN
dti-1297	170	15	et	et	PROPN
dti-1297	170	16	al	al	PROPN
dti-1297	170	17	.	.	PROPN
dti-1297	170	18	2003	2003	NUM
dti-1297	170	19	.	.	PUNCT
dti-1297	171	1	nmda	nmda	ADJ
dti-1297	171	2	receptor	receptor	NOUN
dti-1297	171	3	antagonist	antagonist	NOUN
dti-1297	171	4	treatment	treatment	NOUN
dti-1297	171	5	increases	increase	VERB
dti-1297	171	6	the	the	DET
dti-1297	171	7	production	production	NOUN
dti-1297	171	8	of	of	ADP
dti-1297	171	9	new	new	ADJ
dti-1297	171	10	neurons	neuron	NOUN
dti-1297	171	11	in	in	ADP
dti-1297	171	12	the	the	DET
dti-1297	171	13	aged	aged	ADJ
dti-1297	171	14	rat	rat	NOUN
dti-1297	171	15	hippocampus	hippocampus	NOUN
dti-1297	171	16	.	.	PUNCT
dti-1297	172	1	neurobiol	neurobiol	NOUN
dti-1297	172	2	.	.	PUNCT
dti-1297	173	1	aging	aging	NOUN
dti-1297	173	2	,	,	PUNCT
dti-1297	173	3	24:273–84	24:273–84	NOUN
dti-1297	173	4	.	.	PUNCT
dti-1297	174	1	pluchino	pluchino	PROPN
dti-1297	174	2	,	,	PUNCT
dti-1297	174	3	s.	s.	PROPN
dti-1297	174	4	,	,	PUNCT
dti-1297	174	5	quattrini	quattrini	PROPN
dti-1297	174	6	,	,	PUNCT
dti-1297	174	7	a.	a.	NOUN
dti-1297	174	8	and	and	CCONJ
dti-1297	174	9	brambilla	brambilla	NOUN
dti-1297	174	10	,	,	PUNCT
dti-1297	174	11	e.	e.	PROPN
dti-1297	174	12	et	et	PROPN
dti-1297	174	13	al	al	PROPN
dti-1297	174	14	.	.	PROPN
dti-1297	174	15	2003	2003	NUM
dti-1297	174	16	.	.	PUNCT
dti-1297	175	1	injection	injection	NOUN
dti-1297	175	2	of	of	ADP
dti-1297	175	3	adult	adult	NOUN
dti-1297	175	4	neurospheres	neurosphere	NOUN
dti-1297	175	5	induces	induce	VERB
dti-1297	175	6	recovery	recovery	NOUN
dti-1297	175	7	in	in	ADP
dti-1297	175	8	a	a	DET
dti-1297	175	9	chronic	chronic	ADJ
dti-1297	175	10	model	model	NOUN
dti-1297	175	11	of	of	ADP
dti-1297	175	12	multiple	multiple	ADJ
dti-1297	175	13	sclerosis	sclerosis	NOUN
dti-1297	175	14	.	.	PUNCT
dti-1297	176	1	nature	nature	NOUN
dti-1297	176	2	,	,	PUNCT
dti-1297	176	3	422:688–94	422:688–94	PROPN
dti-1297	176	4	.	.	PUNCT
dti-1297	176	5	santarelli	santarelli	PROPN
dti-1297	176	6	,	,	PUNCT
dti-1297	176	7	l.	l.	PROPN
dti-1297	176	8	,	,	PUNCT
dti-1297	176	9	saxe	saxe	NOUN
dti-1297	176	10	,	,	PUNCT
dti-1297	176	11	m.	m.	NOUN
dti-1297	176	12	and	and	CCONJ
dti-1297	176	13	gross	gross	NOUN
dti-1297	176	14	,	,	PUNCT
dti-1297	176	15	c.	c.	PROPN
dti-1297	176	16	et	et	PROPN
dti-1297	176	17	al	al	PROPN
dti-1297	176	18	.	.	PROPN
dti-1297	176	19	2003	2003	NUM
dti-1297	176	20	.	.	PUNCT
dti-1297	177	1	requirement	requirement	NOUN
dti-1297	177	2	of	of	ADP
dti-1297	177	3	hippocampal	hippocampal	ADJ
dti-1297	177	4	neurogenesis	neurogenesis	NOUN
dti-1297	177	5	for	for	ADP
dti-1297	177	6	the	the	DET
dti-1297	177	7	behavioral	behavioral	ADJ
dti-1297	177	8	effects	effect	NOUN
dti-1297	177	9	of	of	ADP
dti-1297	177	10	antidepressants	antidepressant	NOUN
dti-1297	177	11	.	.	PUNCT
dti-1297	178	1	science	science	NOUN
dti-1297	178	2	,	,	PUNCT
dti-1297	178	3	301:805–9	301:805–9	NUM
dti-1297	178	4	.	.	PUNCT
dti-1297	178	5	scarpini	scarpini	PROPN
dti-1297	178	6	,	,	PUNCT
dti-1297	178	7	e.	e.	PROPN
dti-1297	178	8	,	,	PUNCT
dti-1297	178	9	scheltens	schelten	VERB
dti-1297	178	10	,	,	PUNCT
dti-1297	178	11	p.	p.	NOUN
dti-1297	178	12	and	and	CCONJ
dti-1297	178	13	feldman	feldman	PROPN
dti-1297	178	14	,	,	PUNCT
dti-1297	178	15	h.	h.	PROPN
dti-1297	178	16	2003	2003	NUM
dti-1297	178	17	.	.	PUNCT
dti-1297	179	1	treatment	treatment	NOUN
dti-1297	179	2	of	of	ADP
dti-1297	179	3	alzheimer	alzheimer	PROPN
dti-1297	179	4	’s	’s	PART
dti-1297	179	5	disease	disease	NOUN
dti-1297	179	6	:	:	PUNCT
dti-1297	179	7	current	current	ADJ
dti-1297	179	8	status	status	NOUN
dti-1297	179	9	and	and	CCONJ
dti-1297	179	10	new	new	ADJ
dti-1297	179	11	perspectives	perspective	NOUN
dti-1297	179	12	.	.	PUNCT
dti-1297	180	1	lancet	lancet	VERB
dti-1297	180	2	.	.	PUNCT
dti-1297	181	1	neurol	neurol	NOUN
dti-1297	181	2	.	.	PUNCT
dti-1297	181	3	,	,	PUNCT
dti-1297	181	4	2:539–47	2:539–47	X
dti-1297	181	5	.	.	X
dti-1297	181	6	shihabuddin	shihabuddin	ADJ
dti-1297	181	7	,	,	PUNCT
dti-1297	181	8	l.s	l.s	PROPN
dti-1297	181	9	.	.	PROPN
dti-1297	181	10	,	,	PUNCT
dti-1297	181	11	horner	horner	PROPN
dti-1297	181	12	,	,	PUNCT
dti-1297	181	13	p.j	p.j	PROPN
dti-1297	181	14	.	.	PROPN
dti-1297	181	15	and	and	CCONJ
dti-1297	181	16	ray	ray	PROPN
dti-1297	181	17	,	,	PUNCT
dti-1297	181	18	j.	j.	PROPN
dti-1297	181	19	et	et	PROPN
dti-1297	181	20	al	al	PROPN
dti-1297	181	21	.	.	PROPN
dti-1297	181	22	2000	2000	NUM
dti-1297	181	23	.	.	PUNCT
dti-1297	182	1	adult	adult	NOUN
dti-1297	182	2	spinal	spinal	NOUN
dti-1297	182	3	cord	cord	NOUN
dti-1297	182	4	stem	stem	NOUN
dti-1297	182	5	cells	cell	NOUN
dti-1297	182	6	generate	generate	VERB
dti-1297	182	7	neurons	neuron	NOUN
dti-1297	182	8	after	after	ADP
dti-1297	182	9	transplantation	transplantation	NOUN
dti-1297	182	10	in	in	ADP
dti-1297	182	11	the	the	DET
dti-1297	182	12	adult	adult	NOUN
dti-1297	182	13	dentate	dentate	NOUN
dti-1297	182	14	gyrus	gyrus	NOUN
dti-1297	182	15	.	.	PUNCT
dti-1297	183	1	j.	j.	PROPN
dti-1297	183	2	neurosci	neurosci	PROPN
dti-1297	183	3	.	.	PROPN
dti-1297	183	4	,	,	PUNCT
dti-1297	183	5	20:8727–35	20:8727–35	NUM
dti-1297	183	6	.	.	PUNCT
dti-1297	183	7	st	st	PROPN
dti-1297	183	8	.	.	PROPN
dti-1297	183	9	george	george	PROPN
dti-1297	183	10	-	-	PUNCT
dti-1297	183	11	hyslop	hyslop	PROPN
dti-1297	183	12	,	,	PUNCT
dti-1297	183	13	p.h	p.h	PROPN
dti-1297	183	14	.	.	PROPN
dti-1297	183	15	and	and	CCONJ
dti-1297	183	16	petit	petit	NOUN
dti-1297	183	17	,	,	PUNCT
dti-1297	183	18	a.	a.	NOUN
dti-1297	183	19	2005	2005	NUM
dti-1297	183	20	.	.	PUNCT
dti-1297	184	1	molecular	molecular	ADJ
dti-1297	184	2	biology	biology	NOUN
dti-1297	184	3	and	and	CCONJ
dti-1297	184	4	genetics	genetic	NOUN
dti-1297	184	5	of	of	ADP
dti-1297	184	6	alzheimer	alzheimer	PROPN
dti-1297	184	7	’s	’s	PART
dti-1297	184	8	disease	disease	NOUN
dti-1297	184	9	.	.	PUNCT
dti-1297	185	1	c.r	c.r	PROPN
dti-1297	185	2	.	.	PROPN
dti-1297	185	3	biol	biol	PROPN
dti-1297	185	4	.	.	PUNCT
dti-1297	185	5	,	,	PUNCT
dti-1297	186	1	328:119–30	328:119–30	NUM
dti-1297	186	2	.	.	PUNCT
dti-1297	187	1	taupin	taupin	NOUN
dti-1297	187	2	,	,	PUNCT
dti-1297	187	3	p.	p.	NOUN
dti-1297	187	4	and	and	CCONJ
dti-1297	187	5	gage	gage	NOUN
dti-1297	187	6	,	,	PUNCT
dti-1297	187	7	f.h	f.h	PROPN
dti-1297	187	8	.	.	PROPN
dti-1297	187	9	2002	2002	NUM
dti-1297	187	10	.	.	PUNCT
dti-1297	188	1	adult	adult	NOUN
dti-1297	188	2	neurogenesis	neurogenesis	NOUN
dti-1297	188	3	and	and	CCONJ
dti-1297	188	4	neural	neural	ADJ
dti-1297	188	5	stem	stem	NOUN
dti-1297	188	6	cells	cell	NOUN
dti-1297	188	7	of	of	ADP
dti-1297	188	8	the	the	DET
dti-1297	188	9	central	central	ADJ
dti-1297	188	10	nervous	nervous	ADJ
dti-1297	188	11	system	system	NOUN
dti-1297	188	12	in	in	ADP
dti-1297	188	13	mammals	mammal	NOUN
dti-1297	188	14	.	.	PUNCT
dti-1297	189	1	j.	j.	PROPN
dti-1297	189	2	neurosci	neurosci	PROPN
dti-1297	189	3	.	.	PUNCT
dti-1297	190	1	res	re	NOUN
dti-1297	190	2	.	.	PROPN
dti-1297	190	3	,	,	PUNCT
dti-1297	190	4	69:745–9	69:745–9	NUM
dti-1297	190	5	.	.	PUNCT
dti-1297	191	1	taupin	taupin	NOUN
dti-1297	191	2	,	,	PUNCT
dti-1297	191	3	p.	p.	NOUN
dti-1297	191	4	2005	2005	NUM
dti-1297	191	5	.	.	PUNCT
dti-1297	192	1	consideration	consideration	NOUN
dti-1297	192	2	of	of	ADP
dti-1297	192	3	adult	adult	NOUN
dti-1297	192	4	neurogenesis	neurogenesis	NOUN
dti-1297	192	5	from	from	ADP
dti-1297	192	6	basic	basic	ADJ
dti-1297	192	7	science	science	NOUN
dti-1297	192	8	to	to	ADP
dti-1297	192	9	therapy	therapy	NOUN
dti-1297	192	10	.	.	PUNCT
dti-1297	193	1	med	med	PROPN
dti-1297	193	2	.	.	PUNCT
dti-1297	194	1	sci	sci	PROPN
dti-1297	194	2	.	.	PUNCT
dti-1297	194	3	monit	monit	PROPN
dti-1297	194	4	.	.	PUNCT
dti-1297	194	5	,	,	PUNCT
dti-1297	194	6	11	11	NUM
dti-1297	194	7	:	:	PUNCT
dti-1297	194	8	le16–17	le16–17	NUM
dti-1297	194	9	.	.	PUNCT
dti-1297	195	1	taupin	taupin	NOUN
dti-1297	195	2	,	,	PUNCT
dti-1297	195	3	p.	p.	NOUN
dti-1297	195	4	2006	2006	NUM
dti-1297	195	5	.	.	PUNCT
dti-1297	196	1	adult	adult	NOUN
dti-1297	196	2	neurogenesis	neurogenesis	NOUN
dti-1297	196	3	and	and	CCONJ
dti-1297	196	4	neuroplasticity	neuroplasticity	NOUN
dti-1297	196	5	.	.	PUNCT
dti-1297	197	1	restor	restor	NOUN
dti-1297	197	2	.	.	PUNCT
dti-1297	198	1	neurol	neurol	PROPN
dti-1297	198	2	.	.	PUNCT
dti-1297	199	1	neurosci	neurosci	PROPN
dti-1297	199	2	.	.	PUNCT
dti-1297	199	3	,	,	PUNCT
dti-1297	200	1	24:9–15	24:9–15	X
dti-1297	200	2	.	.	PUNCT
dti-1297	201	1	wen	wen	PROPN
dti-1297	201	2	,	,	PUNCT
dti-1297	201	3	p.h	p.h	PROPN
dti-1297	201	4	.	.	PROPN
dti-1297	201	5	,	,	PUNCT
dti-1297	201	6	shao	shao	PROPN
dti-1297	201	7	,	,	PUNCT
dti-1297	201	8	x.	x.	NOUN
dti-1297	201	9	and	and	CCONJ
dti-1297	201	10	shao	shao	PROPN
dti-1297	201	11	,	,	PUNCT
dti-1297	201	12	z.	z.	PROPN
dti-1297	201	13	et	et	PROPN
dti-1297	201	14	al	al	PROPN
dti-1297	201	15	.	.	PROPN
dti-1297	201	16	2002	2002	NUM
dti-1297	201	17	.	.	PUNCT
dti-1297	202	1	overexpression	overexpression	NOUN
dti-1297	202	2	of	of	ADP
dti-1297	202	3	wild	wild	ADJ
dti-1297	202	4	type	type	NOUN
dti-1297	202	5	but	but	CCONJ
dti-1297	202	6	not	not	PART
dti-1297	202	7	an	an	DET
dti-1297	202	8	fad	fad	NOUN
dti-1297	202	9	mutant	mutant	NOUN
dti-1297	202	10	presenilin-1	presenilin-1	NUM
dti-1297	202	11	promotes	promote	VERB
dti-1297	202	12	neurogenesis	neurogenesis	NOUN
dti-1297	202	13	in	in	ADP
dti-1297	202	14	the	the	DET
dti-1297	202	15	hippocampus	hippocampus	NOUN
dti-1297	202	16	of	of	ADP
dti-1297	202	17	adult	adult	NOUN
dti-1297	202	18	mice	mouse	NOUN
dti-1297	202	19	.	.	PUNCT
dti-1297	203	1	neurobiol	neurobiol	NOUN
dti-1297	203	2	.	.	PUNCT
dti-1297	204	1	dis	dis	PROPN
dti-1297	204	2	.	.	PROPN
dti-1297	204	3	,	,	PUNCT
dti-1297	205	1	10:8–19	10:8–19	NUM
dti-1297	205	2	.	.	PUNCT
dti-1297	206	1	wilkinson	wilkinson	PROPN
dti-1297	206	2	,	,	PUNCT
dti-1297	206	3	d.g	d.g	PROPN
dti-1297	206	4	.	.	PROPN
dti-1297	206	5	,	,	PUNCT
dti-1297	206	6	francis	francis	PROPN
dti-1297	206	7	,	,	PUNCT
dti-1297	206	8	p.t	p.t	PROPN
dti-1297	206	9	.	.	PROPN
dti-1297	206	10	and	and	CCONJ
dti-1297	206	11	schwam	schwam	ADJ
dti-1297	206	12	,	,	PUNCT
dti-1297	206	13	e.	e.	PROPN
dti-1297	206	14	et	et	PROPN
dti-1297	206	15	al	al	PROPN
dti-1297	206	16	.	.	PROPN
dti-1297	206	17	2004	2004	NUM
dti-1297	206	18	.	.	PUNCT
dti-1297	207	1	cholinesterase	cholinesterase	NOUN
dti-1297	207	2	inhibitors	inhibitor	NOUN
dti-1297	207	3	used	use	VERB
dti-1297	207	4	in	in	ADP
dti-1297	207	5	the	the	DET
dti-1297	207	6	treatment	treatment	NOUN
dti-1297	207	7	of	of	ADP
dti-1297	207	8	alzheimer	alzheimer	PROPN
dti-1297	207	9	’s	’s	PART
dti-1297	207	10	disease	disease	NOUN
dti-1297	207	11	:	:	PUNCT
dti-1297	207	12	the	the	DET
dti-1297	207	13	relationship	relationship	NOUN
dti-1297	207	14	between	between	ADP
dti-1297	207	15	pharmacological	pharmacological	ADJ
dti-1297	207	16	effects	effect	NOUN
dti-1297	207	17	and	and	CCONJ
dti-1297	207	18	clinical	clinical	ADJ
dti-1297	207	19	effi	effi	PROPN
dti-1297	207	20	cacy	cacy	NOUN
dti-1297	207	21	.	.	PUNCT
dti-1297	208	1	drugs	drug	NOUN
dti-1297	208	2	aging	aging	NOUN
dti-1297	208	3	,	,	PUNCT
dti-1297	208	4	21:453–78	21:453–78	NUM
dti-1297	208	5	.	.	PUNCT
dti-1297	209	1	yang	yang	PROPN
dti-1297	209	2	,	,	PUNCT
dti-1297	209	3	y.	y.	PROPN
dti-1297	209	4	,	,	PUNCT
dti-1297	209	5	geldmacher	geldmacher	PROPN
dti-1297	209	6	,	,	PUNCT
dti-1297	209	7	d.s	d.s	PROPN
dti-1297	209	8	.	.	PROPN
dti-1297	209	9	and	and	CCONJ
dti-1297	209	10	herrup	herrup	NOUN
dti-1297	209	11	,	,	PUNCT
dti-1297	209	12	k.	k.	PROPN
dti-1297	209	13	2001	2001	NUM
dti-1297	209	14	.	.	PUNCT
dti-1297	210	1	dna	dna	PROPN
dti-1297	210	2	replication	replication	NOUN
dti-1297	210	3	precedes	precede	VERB
dti-1297	210	4	neuronal	neuronal	ADJ
dti-1297	210	5	cell	cell	NOUN
dti-1297	210	6	death	death	NOUN
dti-1297	210	7	in	in	ADP
dti-1297	210	8	alzheimer	alzheimer	PROPN
dti-1297	210	9	’s	’s	PART
dti-1297	210	10	disease	disease	NOUN
dti-1297	210	11	.	.	PUNCT
dti-1297	211	1	j.	j.	PROPN
dti-1297	211	2	neurosci	neurosci	PROPN
dti-1297	211	3	.	.	PROPN
dti-1297	211	4	,	,	PUNCT
dti-1297	211	5	21:2661–8	21:2661–8	NUM
dti-1297	211	6	.	.	PUNCT