id	sid	tid	token	lemma	pos
dti-1313	1	1	satoh	satoh	NOUN
dti-1313	1	2	et	et	NOUN
dti-1313	1	3	al.indd	al.indd	X
dti-1313	1	4	review	review	VERB
dti-1313	1	5	correspondence	correspondence	NOUN
dti-1313	1	6	:	:	PUNCT
dti-1313	1	7	dr	dr	PROPN
dti-1313	1	8	.	.	PROPN
dti-1313	1	9	hiroyasu	hiroyasu	PROPN
dti-1313	1	10	satoh	satoh	PROPN
dti-1313	1	11	,	,	PUNCT
dti-1313	1	12	department	department	NOUN
dti-1313	1	13	of	of	ADP
dti-1313	1	14	pharmacology	pharmacology	NOUN
dti-1313	1	15	,	,	PUNCT
dti-1313	1	16	nara	nara	PROPN
dti-1313	1	17	medical	medical	PROPN
dti-1313	1	18	university	university	PROPN
dti-1313	1	19	,	,	PUNCT
dti-1313	1	20	kashihara	kashihara	PROPN
dti-1313	1	21	,	,	PUNCT
dti-1313	1	22	nara	nara	PROPN
dti-1313	1	23	634	634	NUM
dti-1313	1	24	-	-	SYM
dti-1313	1	25	8521	8521	NUM
dti-1313	1	26	,	,	PUNCT
dti-1313	1	27	japan	japan	PROPN
dti-1313	1	28	.	.	PUNCT
dti-1313	2	1	tel	tel	ADP
dti-1313	2	2	:	:	PUNCT
dti-1313	2	3	+81	+81	NUM
dti-1313	2	4	-	-	PUNCT
dti-1313	2	5	744	744	NUM
dti-1313	2	6	-	-	SYM
dti-1313	2	7	29	29	NUM
dti-1313	2	8	-	-	SYM
dti-1313	2	9	8831	8831	NUM
dti-1313	2	10	;	;	PUNCT
dti-1313	2	11	fax	fax	NOUN
dti-1313	2	12	:	:	PUNCT
dti-1313	2	13	+81	+81	ADJ
dti-1313	2	14	-	-	PUNCT
dti-1313	2	15	744	744	NUM
dti-1313	2	16	-	-	SYM
dti-1313	2	17	29	29	NUM
dti-1313	2	18	-	-	SYM
dti-1313	2	19	0510	0510	NUM
dti-1313	2	20	;	;	PUNCT
dti-1313	2	21	email	email	NOUN
dti-1313	2	22	:	:	PUNCT
dti-1313	2	23	hysat@naramed-u.ac.jp	hysat@naramed-u.ac.jp	SCONJ
dti-1313	2	24	please	please	INTJ
dti-1313	2	25	note	note	VERB
dti-1313	2	26	that	that	SCONJ
dti-1313	2	27	this	this	DET
dti-1313	2	28	article	article	NOUN
dti-1313	2	29	may	may	AUX
dti-1313	2	30	not	not	PART
dti-1313	2	31	be	be	AUX
dti-1313	2	32	used	use	VERB
dti-1313	2	33	for	for	ADP
dti-1313	2	34	commercial	commercial	ADJ
dti-1313	2	35	purposes	purpose	NOUN
dti-1313	2	36	.	.	PUNCT
dti-1313	3	1	for	for	ADP
dti-1313	3	2	further	further	ADJ
dti-1313	3	3	information	information	NOUN
dti-1313	3	4	please	please	INTJ
dti-1313	3	5	refer	refer	VERB
dti-1313	3	6	to	to	ADP
dti-1313	3	7	the	the	DET
dti-1313	3	8	copyright	copyright	NOUN
dti-1313	3	9	statement	statement	NOUN
dti-1313	3	10	at	at	ADP
dti-1313	3	11	http://www.la-press.com/copyright.htm	http://www.la-press.com/copyright.htm	PROPN
dti-1313	3	12	cardiovascular	cardiovascular	ADJ
dti-1313	3	13	pharmacology	pharmacology	NOUN
dti-1313	3	14	of	of	ADP
dti-1313	3	15	sinomenine	sinomenine	NOUN
dti-1313	3	16	:	:	PUNCT
dti-1313	3	17	the	the	DET
dti-1313	3	18	mechanical	mechanical	ADJ
dti-1313	3	19	and	and	CCONJ
dti-1313	3	20	electropharmacological	electropharmacological	ADJ
dti-1313	3	21	actions	action	NOUN
dti-1313	3	22	seiichiro	seiichiro	VERB
dti-1313	3	23	nishida	nishida	ADJ
dti-1313	3	24	and	and	CCONJ
dti-1313	3	25	hiroyasu	hiroyasu	PROPN
dti-1313	3	26	satoh	satoh	NOUN
dti-1313	3	27	department	department	NOUN
dti-1313	3	28	of	of	ADP
dti-1313	3	29	pharmacology	pharmacology	NOUN
dti-1313	3	30	,	,	PUNCT
dti-1313	3	31	division	division	NOUN
dti-1313	3	32	of	of	ADP
dti-1313	3	33	traditional	traditional	ADJ
dti-1313	3	34	medicine	medicine	NOUN
dti-1313	3	35	,	,	PUNCT
dti-1313	3	36	nara	nara	PROPN
dti-1313	3	37	medical	medical	PROPN
dti-1313	3	38	university	university	PROPN
dti-1313	3	39	,	,	PUNCT
dti-1313	3	40	kashihara	kashihara	PROPN
dti-1313	3	41	,	,	PUNCT
dti-1313	3	42	nara	nara	PROPN
dti-1313	3	43	634	634	NUM
dti-1313	3	44	-	-	SYM
dti-1313	3	45	8521	8521	NUM
dti-1313	3	46	,	,	PUNCT
dti-1313	3	47	japan	japan	PROPN
dti-1313	3	48	abstract	abstract	PROPN
dti-1313	3	49	:	:	PUNCT
dti-1313	3	50	sinomenine	sinomenine	NOUN
dti-1313	3	51	is	be	AUX
dti-1313	3	52	one	one	NUM
dti-1313	3	53	of	of	ADP
dti-1313	3	54	the	the	DET
dti-1313	3	55	alkaloids	alkaloid	NOUN
dti-1313	3	56	extracted	extract	VERB
dti-1313	3	57	from	from	ADP
dti-1313	3	58	chinese	chinese	ADJ
dti-1313	3	59	medical	medical	ADJ
dti-1313	3	60	plant	plant	NOUN
dti-1313	3	61	,	,	PUNCT
dti-1313	3	62	sinomenium	sinomenium	NOUN
dti-1313	3	63	acutum	acutum	PROPN
dti-1313	3	64	rehder	rehder	PROPN
dti-1313	3	65	et	et	PROPN
dti-1313	3	66	wilson	wilson	PROPN
dti-1313	3	67	.	.	PUNCT
dti-1313	4	1	sinomenine	sinomenine	PROPN
dti-1313	4	2	has	have	AUX
dti-1313	4	3	been	be	AUX
dti-1313	4	4	used	use	VERB
dti-1313	4	5	for	for	ADP
dti-1313	4	6	rheumatoid	rheumatoid	VERB
dti-1313	4	7	arthritis	arthritis	NOUN
dti-1313	4	8	as	as	ADP
dti-1313	4	9	an	an	DET
dti-1313	4	10	anti	anti	ADJ
dti-1313	4	11	-	-	ADJ
dti-1313	4	12	infl	infl	ADJ
dti-1313	4	13	ammatory	ammatory	NOUN
dti-1313	4	14	and	and	CCONJ
dti-1313	4	15	immunomodulative	immunomodulative	ADJ
dti-1313	4	16	drugs	drug	NOUN
dti-1313	4	17	.	.	PUNCT
dti-1313	5	1	we	we	PRON
dti-1313	5	2	have	have	AUX
dti-1313	5	3	so	so	ADV
dti-1313	5	4	far	far	ADV
dti-1313	5	5	been	be	AUX
dti-1313	5	6	investigated	investigate	VERB
dti-1313	5	7	the	the	DET
dti-1313	5	8	cardiovascular	cardiovascular	ADJ
dti-1313	5	9	pharmacological	pharmacological	ADJ
dti-1313	5	10	actions	action	NOUN
dti-1313	5	11	of	of	ADP
dti-1313	5	12	sinomenine	sinomenine	NOUN
dti-1313	5	13	.	.	PUNCT
dti-1313	6	1	sinomenine	sinomenine	PROPN
dti-1313	6	2	dilated	dilated	ADJ
dti-1313	6	3	ne	ne	NOUN
dti-1313	6	4	(	(	PUNCT
dti-1313	6	5	5	5	NUM
dti-1313	6	6	µm)-	µm)-	PROPN
dti-1313	6	7	,	,	PUNCT
dti-1313	6	8	kcl	kcl	X
dti-1313	6	9	(	(	PUNCT
dti-1313	6	10	60	60	NUM
dti-1313	6	11	mm)and	mm)and	NOUN
dti-1313	6	12	pdb	pdb	PROPN
dti-1313	6	13	(	(	PUNCT
dti-1313	6	14	300	300	NUM
dti-1313	6	15	nm)-induced	nm)-induced	ADJ
dti-1313	6	16	vasoconstrictions	vasoconstriction	NOUN
dti-1313	6	17	.	.	PUNCT
dti-1313	7	1	the	the	DET
dti-1313	7	2	pretreatment	pretreatment	NOUN
dti-1313	7	3	with	with	ADP
dti-1313	7	4	nicardipine	nicardipine	PROPN
dti-1313	7	5	(	(	PUNCT
dti-1313	7	6	0.1	0.1	NUM
dti-1313	7	7	µm	µm	NOUN
dti-1313	7	8	)	)	PUNCT
dti-1313	7	9	,	,	PUNCT
dti-1313	7	10	staurosporine	staurosporine	NOUN
dti-1313	7	11	(	(	PUNCT
dti-1313	7	12	30	30	NUM
dti-1313	7	13	nm	nm	NOUN
dti-1313	7	14	)	)	PUNCT
dti-1313	7	15	,	,	PUNCT
dti-1313	7	16	l	l	PROPN
dti-1313	7	17	-	-	NOUN
dti-1313	7	18	nmma	nmma	PROPN
dti-1313	7	19	(	(	PUNCT
dti-1313	7	20	100	100	NUM
dti-1313	7	21	µm	µm	NOUN
dti-1313	7	22	)	)	PUNCT
dti-1313	7	23	,	,	PUNCT
dti-1313	7	24	indomethacin	indomethacin	X
dti-1313	7	25	(	(	PUNCT
dti-1313	7	26	10	10	NUM
dti-1313	7	27	µm	µm	NOUN
dti-1313	7	28	)	)	PUNCT
dti-1313	7	29	or	or	CCONJ
dti-1313	7	30	propranolol	propranolol	NOUN
dti-1313	7	31	signifi	signifi	NOUN
dti-1313	7	32	cantly	cantly	ADV
dti-1313	7	33	attenuated	attenuate	VERB
dti-1313	7	34	the	the	DET
dti-1313	7	35	sinomenine	sinomenine	NOUN
dti-1313	7	36	-	-	PUNCT
dti-1313	7	37	induced	induce	VERB
dti-1313	7	38	vasorelaxation	vasorelaxation	NOUN
dti-1313	7	39	.	.	PUNCT
dti-1313	8	1	therefore	therefore	ADV
dti-1313	8	2	,	,	PUNCT
dti-1313	8	3	these	these	DET
dti-1313	8	4	results	result	NOUN
dti-1313	8	5	indicate	indicate	VERB
dti-1313	8	6	that	that	DET
dti-1313	8	7	sinomenine	sinomenine	NOUN
dti-1313	8	8	causes	cause	VERB
dti-1313	8	9	the	the	DET
dti-1313	8	10	vasorelaxation	vasorelaxation	NOUN
dti-1313	8	11	by	by	ADP
dti-1313	8	12	the	the	DET
dti-1313	8	13	involvement	involvement	NOUN
dti-1313	8	14	with	with	ADP
dti-1313	8	15	the	the	DET
dti-1313	8	16	inhibitions	inhibition	NOUN
dti-1313	8	17	of	of	ADP
dti-1313	8	18	ca2	ca2	PROPN
dti-1313	8	19	+	+	PROPN
dti-1313	8	20	current	current	ADJ
dti-1313	8	21	(	(	PUNCT
dti-1313	8	22	ica	ica	PROPN
dti-1313	8	23	)	)	PUNCT
dti-1313	8	24	and	and	CCONJ
dti-1313	8	25	pk	pk	PROPN
dti-1313	8	26	-	-	PUNCT
dti-1313	8	27	c	c	NOUN
dti-1313	8	28	,	,	PUNCT
dti-1313	8	29	β	β	X
dti-1313	8	30	-	-	PUNCT
dti-1313	8	31	adrenoceptor	adrenoceptor	NOUN
dti-1313	8	32	stimulation	stimulation	NOUN
dti-1313	8	33	,	,	PUNCT
dti-1313	8	34	and	and	CCONJ
dti-1313	8	35	the	the	DET
dti-1313	8	36	activation	activation	NOUN
dti-1313	8	37	of	of	ADP
dti-1313	8	38	no	no	PRON
dti-1313	8	39	and	and	CCONJ
dti-1313	8	40	pgi2	pgi2	PROPN
dti-1313	8	41	syntheses	synthesis	NOUN
dti-1313	8	42	in	in	ADP
dti-1313	8	43	endothelium	endothelium	NOUN
dti-1313	8	44	.	.	PUNCT
dti-1313	9	1	on	on	ADP
dti-1313	9	2	the	the	DET
dti-1313	9	3	other	other	ADJ
dti-1313	9	4	hand	hand	NOUN
dti-1313	9	5	,	,	PUNCT
dti-1313	9	6	in	in	ADP
dti-1313	9	7	the	the	DET
dti-1313	9	8	ventricular	ventricular	ADJ
dti-1313	9	9	cardiomyocytes	cardiomyocyte	NOUN
dti-1313	9	10	of	of	ADP
dti-1313	9	11	guinea	guinea	NOUN
dti-1313	9	12	pig	pig	NOUN
dti-1313	9	13	,	,	PUNCT
dti-1313	9	14	sinomenine	sinomenine	NOUN
dti-1313	9	15	inhibits	inhibit	VERB
dti-1313	9	16	ica	ica	PROPN
dti-1313	9	17	and	and	CCONJ
dti-1313	9	18	simultaneously	simultaneously	ADV
dti-1313	9	19	decreases	decrease	VERB
dti-1313	9	20	the	the	DET
dti-1313	9	21	delayed	delay	VERB
dti-1313	9	22	rectifi	rectifi	NOUN
dti-1313	9	23	er	er	INTJ
dti-1313	9	24	k+	k+	PROPN
dti-1313	9	25	current	current	ADJ
dti-1313	9	26	(	(	PUNCT
dti-1313	9	27	ik	ik	PROPN
dti-1313	9	28	)	)	PUNCT
dti-1313	9	29	,	,	PUNCT
dti-1313	9	30	resulting	result	VERB
dti-1313	9	31	in	in	ADP
dti-1313	9	32	the	the	DET
dti-1313	9	33	prolongation	prolongation	NOUN
dti-1313	9	34	of	of	ADP
dti-1313	9	35	action	action	NOUN
dti-1313	9	36	potential	potential	ADJ
dti-1313	9	37	duration	duration	NOUN
dti-1313	9	38	.	.	PUNCT
dti-1313	10	1	sinomenine	sinomenine	NOUN
dti-1313	10	2	also	also	ADV
dti-1313	10	3	suppresses	suppress	VERB
dti-1313	10	4	the	the	DET
dti-1313	10	5	dysrhysmias	dysrhysmia	NOUN
dti-1313	10	6	induced	induce	VERB
dti-1313	10	7	by	by	ADP
dti-1313	10	8	triggered	trigger	VERB
dti-1313	10	9	activities	activity	NOUN
dti-1313	10	10	under	under	ADP
dti-1313	10	11	the	the	DET
dti-1313	10	12	ca2	ca2	PROPN
dti-1313	10	13	+	+	PROPN
dti-1313	10	14	overload	overload	NOUN
dti-1313	10	15	condition	condition	NOUN
dti-1313	10	16	.	.	PUNCT
dti-1313	11	1	therefore	therefore	ADV
dti-1313	11	2	,	,	PUNCT
dti-1313	11	3	sinomenine	sinomenine	NOUN
dti-1313	11	4	may	may	AUX
dti-1313	11	5	be	be	AUX
dti-1313	11	6	expected	expect	VERB
dti-1313	11	7	as	as	ADP
dti-1313	11	8	one	one	NUM
dti-1313	11	9	of	of	ADP
dti-1313	11	10	effective	effective	ADJ
dti-1313	11	11	therapeutic	therapeutic	ADJ
dti-1313	11	12	drugs	drug	NOUN
dti-1313	11	13	for	for	ADP
dti-1313	11	14	heart	heart	NOUN
dti-1313	11	15	failure	failure	NOUN
dti-1313	11	16	and	and	CCONJ
dti-1313	11	17	dysrhythmias	dysrhythmia	NOUN
dti-1313	11	18	,	,	PUNCT
dti-1313	11	19	and	and	CCONJ
dti-1313	11	20	may	may	AUX
dti-1313	11	21	maintain	maintain	VERB
dti-1313	11	22	the	the	DET
dti-1313	11	23	cardiovascular	cardiovascular	ADJ
dti-1313	11	24	functions	function	NOUN
dti-1313	11	25	due	due	ADP
dti-1313	11	26	to	to	ADP
dti-1313	11	27	modulation	modulation	NOUN
dti-1313	11	28	of	of	ADP
dti-1313	11	29	cardiac	cardiac	ADJ
dti-1313	11	30	ionic	ionic	ADJ
dti-1313	11	31	channels	channel	NOUN
dti-1313	11	32	and	and	CCONJ
dti-1313	11	33	blood	blood	NOUN
dti-1313	11	34	vessels	vessel	NOUN
dti-1313	11	35	.	.	PUNCT
dti-1313	12	1	keywords	keyword	NOUN
dti-1313	12	2	:	:	PUNCT
dti-1313	12	3	sinomenine	sinomenine	NOUN
dti-1313	12	4	,	,	PUNCT
dti-1313	12	5	vasodilation	vasodilation	NOUN
dti-1313	12	6	,	,	PUNCT
dti-1313	12	7	cardioprotective	cardioprotective	ADJ
dti-1313	12	8	action	action	NOUN
dti-1313	12	9	,	,	PUNCT
dti-1313	12	10	ca2	ca2	PROPN
dti-1313	12	11	+	+	PROPN
dti-1313	12	12	channel	channel	NOUN
dti-1313	12	13	,	,	PUNCT
dti-1313	12	14	aorta	aorta	NOUN
dti-1313	12	15	,	,	PUNCT
dti-1313	12	16	cardiomyocytes	cardiomyocytes	ADJ
dti-1313	12	17	introduction	introduction	NOUN
dti-1313	12	18	sinomenine	sinomenine	NOUN
dti-1313	12	19	(	(	PUNCT
dti-1313	12	20	7	7	NUM
dti-1313	12	21	,	,	PUNCT
dti-1313	12	22	8	8	NUM
dti-1313	12	23	-	-	PUNCT
dti-1313	12	24	didehydro-4	didehydro-4	NOUN
dti-1313	12	25	-	-	PUNCT
dti-1313	12	26	hydroxy-3	hydroxy-3	ADJ
dti-1313	12	27	,	,	PUNCT
dti-1313	12	28	7	7	NUM
dti-1313	12	29	-	-	PUNCT
dti-1313	12	30	dimethoxy-17	dimethoxy-17	ADV
dti-1313	12	31	-	-	PUNCT
dti-1313	12	32	methyl-9α,13α,14α	methyl-9α,13α,14α	NOUN
dti-1313	12	33	-	-	PUNCT
dti-1313	12	34	morphinan-6	morphinan-6	NUM
dti-1313	12	35	-	-	PUNCT
dti-1313	12	36	one	one	NUM
dti-1313	12	37	)	)	PUNCT
dti-1313	12	38	is	be	AUX
dti-1313	12	39	one	one	NUM
dti-1313	12	40	of	of	ADP
dti-1313	12	41	the	the	DET
dti-1313	12	42	alkaloids	alkaloid	NOUN
dti-1313	12	43	extracted	extract	VERB
dti-1313	12	44	from	from	ADP
dti-1313	12	45	chinese	chinese	ADJ
dti-1313	12	46	herbs	herb	NOUN
dti-1313	12	47	,	,	PUNCT
dti-1313	12	48	sinomenium	sinomenium	NOUN
dti-1313	12	49	acutum	acutum	PROPN
dti-1313	12	50	rehder	rehder	PROPN
dti-1313	12	51	et	et	PROPN
dti-1313	12	52	wilson	wilson	PROPN
dti-1313	12	53	(	(	PUNCT
dti-1313	12	54	li	li	PROPN
dti-1313	12	55	et	et	PROPN
dti-1313	12	56	al	al	PROPN
dti-1313	12	57	.	.	PROPN
dti-1313	12	58	2004	2004	NUM
dti-1313	12	59	)	)	PUNCT
dti-1313	12	60	or	or	CCONJ
dti-1313	12	61	sinomenium	sinomenium	PROPN
dti-1313	12	62	acutum	acutum	PROPN
dti-1313	12	63	var	var	PROPN
dti-1313	12	64	.	.	PUNCT
dti-1313	13	1	cinereum	cinereum	NOUN
dti-1313	13	2	(	(	PUNCT
dti-1313	13	3	zhao	zhao	PROPN
dti-1313	13	4	et	et	PROPN
dti-1313	13	5	al	al	PROPN
dti-1313	13	6	.	.	PROPN
dti-1313	13	7	2005	2005	NUM
dti-1313	13	8	)	)	PUNCT
dti-1313	13	9	.	.	PUNCT
dti-1313	14	1	in	in	ADP
dti-1313	14	2	chinese	chinese	ADJ
dti-1313	14	3	traditional	traditional	ADJ
dti-1313	14	4	medicine	medicine	NOUN
dti-1313	14	5	,	,	PUNCT
dti-1313	14	6	sinomenine	sinomenine	NOUN
dti-1313	14	7	acutum	acutum	NOUN
dti-1313	14	8	,	,	PUNCT
dti-1313	14	9	a	a	DET
dti-1313	14	10	vine	vine	NOUN
dti-1313	14	11	plant	plant	NOUN
dti-1313	14	12	,	,	PUNCT
dti-1313	14	13	has	have	AUX
dti-1313	14	14	been	be	AUX
dti-1313	14	15	used	use	VERB
dti-1313	14	16	for	for	ADP
dti-1313	14	17	rheumatic	rheumatic	ADJ
dti-1313	14	18	diseases	disease	NOUN
dti-1313	14	19	for	for	ADP
dti-1313	14	20	thousands	thousand	NOUN
dti-1313	14	21	years	year	NOUN
dti-1313	14	22	(	(	PUNCT
dti-1313	14	23	yamasaki	yamasaki	NOUN
dti-1313	14	24	,	,	PUNCT
dti-1313	14	25	1976	1976	NUM
dti-1313	14	26	;	;	PUNCT
dti-1313	14	27	liu	liu	PROPN
dti-1313	14	28	et	et	PROPN
dti-1313	14	29	al	al	PROPN
dti-1313	14	30	.	.	PROPN
dti-1313	14	31	1996	1996	NUM
dti-1313	14	32	)	)	PUNCT
dti-1313	14	33	.	.	PUNCT
dti-1313	15	1	its	its	PRON
dti-1313	15	2	main	main	ADJ
dti-1313	15	3	constituent	constituent	NOUN
dti-1313	15	4	of	of	ADP
dti-1313	15	5	sinomenine	sinomenine	NOUN
dti-1313	15	6	acutum	acutum	NOUN
dti-1313	15	7	is	be	AUX
dti-1313	15	8	sinomenine	sinomenine	NOUN
dti-1313	15	9	,	,	PUNCT
dti-1313	15	10	which	which	PRON
dti-1313	15	11	has	have	AUX
dti-1313	15	12	also	also	ADV
dti-1313	15	13	used	use	VERB
dti-1313	15	14	for	for	ADP
dti-1313	15	15	clinical	clinical	ADJ
dti-1313	15	16	treatment	treatment	NOUN
dti-1313	15	17	of	of	ADP
dti-1313	15	18	rheumatoid	rheumatoid	NOUN
dti-1313	15	19	arthritis	arthritis	NOUN
dti-1313	15	20	(	(	PUNCT
dti-1313	15	21	ra	ra	PROPN
dti-1313	15	22	)	)	PUNCT
dti-1313	15	23	,	,	PUNCT
dti-1313	15	24	due	due	ADP
dti-1313	15	25	to	to	ADP
dti-1313	15	26	the	the	DET
dti-1313	15	27	anti	anti	ADJ
dti-1313	15	28	-	-	ADJ
dti-1313	15	29	infl	infl	ADJ
dti-1313	15	30	ammatory	ammatory	NOUN
dti-1313	15	31	and	and	CCONJ
dti-1313	15	32	immunomodulative	immunomodulative	ADJ
dti-1313	15	33	actions	action	NOUN
dti-1313	15	34	(	(	PUNCT
dti-1313	15	35	yamasaki	yamasaki	NOUN
dti-1313	15	36	,	,	PUNCT
dti-1313	15	37	1976	1976	NUM
dti-1313	15	38	;	;	PUNCT
dti-1313	15	39	liu	liu	PROPN
dti-1313	15	40	et	et	PROPN
dti-1313	15	41	al	al	PROPN
dti-1313	15	42	.	.	PROPN
dti-1313	15	43	1996	1996	NUM
dti-1313	15	44	)	)	PUNCT
dti-1313	15	45	.	.	PUNCT
dti-1313	16	1	we	we	PRON
dti-1313	16	2	have	have	AUX
dti-1313	16	3	already	already	ADV
dti-1313	16	4	investigated	investigate	VERB
dti-1313	16	5	the	the	DET
dti-1313	16	6	cardiovascular	cardiovascular	ADJ
dti-1313	16	7	pharmacological	pharmacological	ADJ
dti-1313	16	8	actions	action	NOUN
dti-1313	16	9	of	of	ADP
dti-1313	16	10	sinomenine	sinomenine	NOUN
dti-1313	16	11	.	.	PUNCT
dti-1313	17	1	mokuboito	mokuboito	PROPN
dti-1313	17	2	(	(	PUNCT
dti-1313	17	3	mu	mu	NOUN
dti-1313	17	4	-	-	PUNCT
dti-1313	17	5	fang	fang	NOUN
dti-1313	17	6	-	-	PUNCT
dti-1313	17	7	yi	yi	NOUN
dti-1313	17	8	-	-	PUNCT
dti-1313	17	9	tang	tang	NOUN
dti-1313	17	10	)	)	PUNCT
dti-1313	17	11	,	,	PUNCT
dti-1313	17	12	a	a	DET
dti-1313	17	13	kind	kind	NOUN
dti-1313	17	14	of	of	ADP
dti-1313	17	15	kampo	kampo	NOUN
dti-1313	17	16	formulation	formulation	NOUN
dti-1313	17	17	containing	contain	VERB
dti-1313	17	18	sinomenium	sinomenium	NOUN
dti-1313	17	19	acutum	acutum	NOUN
dti-1313	17	20	,	,	PUNCT
dti-1313	17	21	has	have	AUX
dti-1313	17	22	been	be	AUX
dti-1313	17	23	used	use	VERB
dti-1313	17	24	for	for	ADP
dti-1313	17	25	heart	heart	NOUN
dti-1313	17	26	failure	failure	NOUN
dti-1313	17	27	(	(	PUNCT
dti-1313	17	28	inaki	inaki	NOUN
dti-1313	17	29	et	et	PROPN
dti-1313	17	30	al	al	PROPN
dti-1313	17	31	.	.	PROPN
dti-1313	17	32	2005	2005	NUM
dti-1313	17	33	)	)	PUNCT
dti-1313	17	34	,	,	PUNCT
dti-1313	17	35	which	which	PRON
dti-1313	17	36	improves	improve	VERB
dti-1313	17	37	heart	heart	NOUN
dti-1313	17	38	failure	failure	NOUN
dti-1313	17	39	symptom	symptom	NOUN
dti-1313	17	40	and	and	CCONJ
dti-1313	17	41	reduces	reduce	VERB
dti-1313	17	42	new	new	PROPN
dti-1313	17	43	york	york	PROPN
dti-1313	17	44	heart	heart	PROPN
dti-1313	17	45	association	association	PROPN
dti-1313	17	46	(	(	PUNCT
dti-1313	17	47	nyha	nyha	PROPN
dti-1313	17	48	)	)	PUNCT
dti-1313	17	49	class	class	NOUN
dti-1313	17	50	and	and	CCONJ
dti-1313	17	51	plasma	plasma	NOUN
dti-1313	17	52	brain	brain	NOUN
dti-1313	17	53	natriuretic	natriuretic	ADJ
dti-1313	17	54	peptide	peptide	NOUN
dti-1313	17	55	(	(	PUNCT
dti-1313	17	56	bnp	bnp	PROPN
dti-1313	17	57	)	)	PUNCT
dti-1313	17	58	concentration	concentration	NOUN
dti-1313	17	59	(	(	PUNCT
dti-1313	17	60	yakubo	yakubo	VERB
dti-1313	17	61	et	et	PROPN
dti-1313	17	62	al	al	PROPN
dti-1313	17	63	.	.	PROPN
dti-1313	17	64	2002	2002	NUM
dti-1313	17	65	)	)	PUNCT
dti-1313	17	66	.	.	PUNCT
dti-1313	18	1	mokuboito	mokuboito	PROPN
dti-1313	18	2	consists	consist	NOUN
dti-1313	18	3	of	of	ADP
dti-1313	18	4	sinomeni	sinomeni	NOUN
dti-1313	18	5	caulis	cauli	NOUN
dti-1313	18	6	et	et	NOUN
dti-1313	18	7	rhizoma	rhizoma	NOUN
dti-1313	18	8	(	(	PUNCT
dti-1313	18	9	rhizome	rhizome	NOUN
dti-1313	18	10	of	of	ADP
dti-1313	18	11	sinomenium	sinomenium	PROPN
dti-1313	18	12	acutum	acutum	PROPN
dti-1313	18	13	rehder	rehder	PROPN
dti-1313	18	14	et	et	PROPN
dti-1313	18	15	wilson	wilson	PROPN
dti-1313	18	16	)	)	PUNCT
dti-1313	18	17	,	,	PUNCT
dti-1313	18	18	cinnamomi	cinnamomi	VERB
dti-1313	18	19	cortex	cortex	NOUN
dti-1313	18	20	(	(	PUNCT
dti-1313	18	21	bark	bark	NOUN
dti-1313	18	22	of	of	ADP
dti-1313	18	23	cinnamomum	cinnamomum	PROPN
dti-1313	18	24	cassia	cassia	NOUN
dti-1313	18	25	blume	blume	PROPN
dti-1313	18	26	)	)	PUNCT
dti-1313	18	27	,	,	PUNCT
dti-1313	18	28	ginseng	ginseng	PROPN
dti-1313	18	29	radix	radix	NOUN
dti-1313	18	30	(	(	PUNCT
dti-1313	18	31	roots	root	NOUN
dti-1313	18	32	of	of	ADP
dti-1313	18	33	panax	panax	PROPN
dti-1313	18	34	ginseng	ginseng	PROPN
dti-1313	18	35	c.	c.	PROPN
dti-1313	18	36	a.	a.	PROPN
dti-1313	18	37	meyer	meyer	PROPN
dti-1313	18	38	)	)	PUNCT
dti-1313	18	39	and	and	CCONJ
dti-1313	18	40	gypsum	gypsum	NOUN
dti-1313	18	41	fibrosum	fibrosum	NOUN
dti-1313	18	42	.	.	PUNCT
dti-1313	19	1	in	in	ADP
dti-1313	19	2	our	our	PRON
dti-1313	19	3	recent	recent	ADJ
dti-1313	19	4	reports	report	NOUN
dti-1313	19	5	(	(	PUNCT
dti-1313	19	6	satoh	satoh	NOUN
dti-1313	19	7	,	,	PUNCT
dti-1313	19	8	2005	2005	NUM
dti-1313	19	9	;	;	PUNCT
dti-1313	19	10	nishida	nishida	NOUN
dti-1313	19	11	and	and	CCONJ
dti-1313	19	12	satoh	satoh	NOUN
dti-1313	19	13	,	,	PUNCT
dti-1313	19	14	2006	2006	NUM
dti-1313	19	15	;	;	PUNCT
dti-1313	19	16	2007	2007	NUM
dti-1313	19	17	)	)	PUNCT
dti-1313	19	18	,	,	PUNCT
dti-1313	19	19	mokuboito	mokuboito	PROPN
dti-1313	19	20	,	,	PUNCT
dti-1313	19	21	sinomenium	sinomenium	ADJ
dti-1313	19	22	acutum	acutum	NOUN
dti-1313	19	23	and	and	CCONJ
dti-1313	19	24	sinomenine	sinomenine	NOUN
dti-1313	19	25	might	might	AUX
dti-1313	19	26	improve	improve	VERB
dti-1313	19	27	chronic	chronic	ADJ
dti-1313	19	28	heart	heart	NOUN
dti-1313	19	29	failure	failure	NOUN
dti-1313	19	30	,	,	PUNCT
dti-1313	19	31	resulting	result	VERB
dti-1313	19	32	from	from	ADP
dti-1313	19	33	the	the	DET
dti-1313	19	34	modulation	modulation	NOUN
dti-1313	19	35	of	of	ADP
dti-1313	19	36	cardiac	cardiac	ADJ
dti-1313	19	37	and	and	CCONJ
dti-1313	19	38	vascular	vascular	ADJ
dti-1313	19	39	systems	system	NOUN
dti-1313	19	40	.	.	PUNCT
dti-1313	20	1	mokuboito	mokuboito	PROPN
dti-1313	20	2	can	can	AUX
dti-1313	20	3	exert	exert	VERB
dti-1313	20	4	the	the	DET
dti-1313	20	5	vasodilating	vasodilate	VERB
dti-1313	20	6	and	and	CCONJ
dti-1313	20	7	cardioprotective	cardioprotective	ADJ
dti-1313	20	8	actions	action	NOUN
dti-1313	20	9	(	(	PUNCT
dti-1313	20	10	satoh	satoh	NOUN
dti-1313	20	11	,	,	PUNCT
dti-1313	20	12	2005	2005	NUM
dti-1313	20	13	)	)	PUNCT
dti-1313	20	14	,	,	PUNCT
dti-1313	20	15	as	as	SCONJ
dti-1313	20	16	discussed	discuss	VERB
dti-1313	20	17	in	in	ADP
dti-1313	20	18	the	the	DET
dti-1313	20	19	following	follow	VERB
dti-1313	20	20	parts	part	NOUN
dti-1313	20	21	.	.	PUNCT
dti-1313	21	1	in	in	ADP
dti-1313	21	2	general	general	ADJ
dti-1313	21	3	,	,	PUNCT
dti-1313	21	4	the	the	DET
dti-1313	21	5	basic	basic	ADJ
dti-1313	21	6	treatments	treatment	NOUN
dti-1313	21	7	of	of	ADP
dti-1313	21	8	heart	heart	NOUN
dti-1313	21	9	failure	failure	NOUN
dti-1313	21	10	consist	consist	NOUN
dti-1313	21	11	of	of	ADP
dti-1313	21	12	(	(	PUNCT
dti-1313	21	13	1	1	X
dti-1313	21	14	)	)	PUNCT
dti-1313	21	15	reducing	reduce	VERB
dti-1313	21	16	workload	workload	NOUN
dti-1313	21	17	of	of	ADP
dti-1313	21	18	heart	heart	NOUN
dti-1313	21	19	,	,	PUNCT
dti-1313	21	20	(	(	PUNCT
dti-1313	21	21	2	2	X
dti-1313	21	22	)	)	PUNCT
dti-1313	21	23	protection	protection	NOUN
dti-1313	21	24	of	of	ADP
dti-1313	21	25	cardiomyocytes	cardiomyocyte	NOUN
dti-1313	21	26	and	and	CCONJ
dti-1313	21	27	(	(	PUNCT
dti-1313	21	28	3	3	X
dti-1313	21	29	)	)	PUNCT
dti-1313	21	30	restriction	restriction	NOUN
dti-1313	21	31	and	and	CCONJ
dti-1313	21	32	control	control	NOUN
dti-1313	21	33	of	of	ADP
dti-1313	21	34	waters	water	NOUN
dti-1313	21	35	and	and	CCONJ
dti-1313	21	36	sodium	sodium	NOUN
dti-1313	21	37	.	.	PUNCT
dti-1313	22	1	in	in	ADP
dti-1313	22	2	order	order	NOUN
dti-1313	22	3	to	to	PART
dti-1313	22	4	reduce	reduce	VERB
dti-1313	22	5	both	both	DET
dti-1313	22	6	preand	preand	NOUN
dti-1313	22	7	after	after	ADP
dti-1313	22	8	-	-	PUNCT
dti-1313	22	9	loads	load	NOUN
dti-1313	22	10	,	,	PUNCT
dti-1313	22	11	the	the	DET
dti-1313	22	12	dilations	dilation	NOUN
dti-1313	22	13	of	of	ADP
dti-1313	22	14	arterioles	arteriole	NOUN
dti-1313	22	15	and	and	CCONJ
dti-1313	22	16	veins	vein	NOUN
dti-1313	22	17	are	be	AUX
dti-1313	22	18	strongly	strongly	ADV
dti-1313	22	19	required	require	VERB
dti-1313	22	20	in	in	ADP
dti-1313	22	21	the	the	DET
dti-1313	22	22	case	case	NOUN
dti-1313	22	23	of	of	ADP
dti-1313	22	24	elevated	elevated	ADJ
dti-1313	22	25	fi	fi	NOUN
dti-1313	22	26	lling	lling	ADJ
dti-1313	22	27	pressures	pressure	NOUN
dti-1313	22	28	and	and	CCONJ
dti-1313	22	29	reduced	reduce	VERB
dti-1313	22	30	cardiac	cardiac	ADJ
dti-1313	22	31	output	output	NOUN
dti-1313	22	32	.	.	PUNCT
dti-1313	23	1	as	as	ADP
dti-1313	23	2	a	a	DET
dti-1313	23	3	cardiovascular	cardiovascular	ADJ
dti-1313	23	4	protective	protective	ADJ
dti-1313	23	5	drug	drug	NOUN
dti-1313	23	6	,	,	PUNCT
dti-1313	23	7	sinomenine	sinomenine	NOUN
dti-1313	23	8	might	might	AUX
dti-1313	23	9	contribute	contribute	VERB
dti-1313	23	10	to	to	ADP
dti-1313	23	11	clinical	clinical	ADJ
dti-1313	23	12	treatments	treatment	NOUN
dti-1313	23	13	via	via	ADP
dti-1313	23	14	modulation	modulation	NOUN
dti-1313	23	15	of	of	ADP
dti-1313	23	16	the	the	DET
dti-1313	23	17	ionic	ionic	ADJ
dti-1313	23	18	currents	current	NOUN
dti-1313	23	19	of	of	ADP
dti-1313	23	20	cardiac	cardiac	ADJ
dti-1313	23	21	cells	cell	NOUN
dti-1313	23	22	,	,	PUNCT
dti-1313	23	23	and	and	CCONJ
dti-1313	23	24	control	control	NOUN
dti-1313	23	25	of	of	ADP
dti-1313	23	26	the	the	DET
dti-1313	23	27	tension	tension	NOUN
dti-1313	23	28	of	of	ADP
dti-1313	23	29	blood	blood	NOUN
dti-1313	23	30	vessels	vessel	NOUN
dti-1313	23	31	.	.	PUNCT
dti-1313	24	1	satoh	satoh	NOUN
dti-1313	24	2	et	et	NOUN
dti-1313	24	3	al.indd	al.indd	X
dti-1313	24	4	1	1	NUM
dti-1313	24	5	5/14/2007	5/14/2007	NUM
dti-1313	24	6	8:58:41	8:58:41	NUM
dti-1313	24	7	pm	pm	NOUN
dti-1313	24	8	97drug	97drug	NUM
dti-1313	24	9	target	target	NOUN
dti-1313	24	10	insights	insight	NOUN
dti-1313	24	11	2007	2007	NUM
dti-1313	24	12	:	:	PUNCT
dti-1313	24	13	2	2	NUM
dti-1313	24	14	97–104	97–104	NUM
dti-1313	24	15	nishida	nishida	NOUN
dti-1313	24	16	and	and	CCONJ
dti-1313	24	17	satoh	satoh	NOUN
dti-1313	24	18	drug	drug	NOUN
dti-1313	24	19	target	target	NOUN
dti-1313	24	20	insights	insight	NOUN
dti-1313	24	21	2007	2007	NUM
dti-1313	24	22	:	:	PUNCT
dti-1313	24	23	2	2	NUM
dti-1313	24	24	in	in	ADP
dti-1313	24	25	this	this	DET
dti-1313	24	26	review	review	NOUN
dti-1313	24	27	,	,	PUNCT
dti-1313	24	28	the	the	DET
dti-1313	24	29	cardiovascular	cardiovascular	ADJ
dti-1313	24	30	pharmacological	pharmacological	ADJ
dti-1313	24	31	actions	action	NOUN
dti-1313	24	32	of	of	ADP
dti-1313	24	33	sinomenine	sinomenine	NOUN
dti-1313	24	34	are	be	AUX
dti-1313	24	35	mainly	mainly	ADV
dti-1313	24	36	shown	show	VERB
dti-1313	24	37	and	and	CCONJ
dti-1313	24	38	discussed	discuss	VERB
dti-1313	24	39	.	.	PUNCT
dti-1313	25	1	source	source	NOUN
dti-1313	25	2	of	of	ADP
dti-1313	25	3	sinomenine	sinomenine	NOUN
dti-1313	25	4	sinomenine	sinomenine	NOUN
dti-1313	25	5	is	be	AUX
dti-1313	25	6	derived	derive	VERB
dti-1313	25	7	from	from	ADP
dti-1313	25	8	natural	natural	ADJ
dti-1313	25	9	plant	plant	NOUN
dti-1313	25	10	such	such	ADJ
dti-1313	25	11	as	as	ADP
dti-1313	25	12	sinomenium	sinomenium	ADJ
dti-1313	25	13	acutum	acutum	NOUN
dti-1313	25	14	(	(	PUNCT
dti-1313	25	15	li	li	PROPN
dti-1313	25	16	et	et	PROPN
dti-1313	25	17	al	al	PROPN
dti-1313	25	18	.	.	PROPN
dti-1313	25	19	2004	2004	NUM
dti-1313	25	20	)	)	PUNCT
dti-1313	25	21	and	and	CCONJ
dti-1313	25	22	sinomenium	sinomenium	PROPN
dti-1313	25	23	acutum	acutum	PROPN
dti-1313	25	24	var	var	PROPN
dti-1313	25	25	.	.	PUNCT
dti-1313	26	1	cinereum	cinereum	NOUN
dti-1313	26	2	(	(	PUNCT
dti-1313	26	3	zhao	zhao	PROPN
dti-1313	26	4	et	et	PROPN
dti-1313	26	5	al	al	PROPN
dti-1313	26	6	.	.	PROPN
dti-1313	26	7	2005	2005	NUM
dti-1313	26	8	)	)	PUNCT
dti-1313	26	9	.	.	PUNCT
dti-1313	27	1	sinomenium	sinomenium	NOUN
dti-1313	27	2	acutum	acutum	PROPN
dti-1313	27	3	and	and	CCONJ
dti-1313	27	4	sinomenium	sinomenium	PROPN
dti-1313	27	5	acutum	acutum	PROPN
dti-1313	27	6	var	var	PROPN
dti-1313	27	7	.	.	PUNCT
dti-1313	28	1	cinereum	cinereum	NOUN
dti-1313	28	2	are	be	AUX
dti-1313	28	3	widely	widely	ADV
dti-1313	28	4	in	in	ADP
dti-1313	28	5	a	a	DET
dti-1313	28	6	lot	lot	NOUN
dti-1313	28	7	of	of	ADP
dti-1313	28	8	regions	region	NOUN
dti-1313	28	9	of	of	ADP
dti-1313	28	10	china	china	PROPN
dti-1313	28	11	.	.	PUNCT
dti-1313	29	1	caulis	caulis	PROPN
dti-1313	29	2	sinomeni	sinomeni	NOUN
dti-1313	29	3	is	be	AUX
dti-1313	29	4	the	the	DET
dti-1313	29	5	dried	dry	VERB
dti-1313	29	6	plant	plant	NOUN
dti-1313	29	7	stems	stem	VERB
dti-1313	29	8	of	of	ADP
dti-1313	29	9	sinomenium	sinomenium	NOUN
dti-1313	29	10	acutum	acutum	NOUN
dti-1313	29	11	and	and	CCONJ
dti-1313	29	12	sinomenium	sinomenium	PROPN
dti-1313	29	13	acutum	acutum	PROPN
dti-1313	29	14	var	var	PROPN
dti-1313	29	15	.	.	PUNCT
dti-1313	30	1	cinereum	cinereum	NOUN
dti-1313	30	2	.	.	PUNCT
dti-1313	31	1	there	there	PRON
dti-1313	31	2	is	be	VERB
dti-1313	31	3	less	less	ADJ
dti-1313	31	4	or	or	CCONJ
dti-1313	31	5	no	no	PRON
dti-1313	31	6	difference	difference	NOUN
dti-1313	31	7	in	in	ADP
dti-1313	31	8	sinomenine	sinomenine	NOUN
dti-1313	31	9	content	content	NOUN
dti-1313	31	10	of	of	ADP
dti-1313	31	11	caulis	cauli	NOUN
dti-1313	31	12	sinomeni	sinomeni	ADJ
dti-1313	31	13	between	between	ADP
dti-1313	31	14	the	the	DET
dti-1313	31	15	species	specie	NOUN
dti-1313	31	16	and	and	CCONJ
dti-1313	31	17	the	the	DET
dti-1313	31	18	varieties	variety	NOUN
dti-1313	31	19	of	of	ADP
dti-1313	31	20	growing	grow	VERB
dti-1313	31	21	regions	region	NOUN
dti-1313	31	22	.	.	PUNCT
dti-1313	32	1	the	the	DET
dti-1313	32	2	variation	variation	NOUN
dti-1313	32	3	is	be	AUX
dti-1313	32	4	found	find	VERB
dti-1313	32	5	among	among	ADP
dti-1313	32	6	the	the	DET
dti-1313	32	7	samples	sample	NOUN
dti-1313	32	8	collected	collect	VERB
dti-1313	32	9	from	from	ADP
dti-1313	32	10	different	different	ADJ
dti-1313	32	11	parts	part	NOUN
dti-1313	32	12	of	of	ADP
dti-1313	32	13	plant	plant	NOUN
dti-1313	32	14	.	.	PUNCT
dti-1313	33	1	the	the	DET
dti-1313	33	2	content	content	NOUN
dti-1313	33	3	of	of	ADP
dti-1313	33	4	sinomenine	sinomenine	NOUN
dti-1313	33	5	is	be	AUX
dti-1313	33	6	dependent	dependent	ADJ
dti-1313	33	7	on	on	ADP
dti-1313	33	8	the	the	DET
dti-1313	33	9	size	size	NOUN
dti-1313	33	10	(	(	PUNCT
dti-1313	33	11	diameter	diameter	NOUN
dti-1313	33	12	)	)	PUNCT
dti-1313	33	13	of	of	ADP
dti-1313	33	14	stem	stem	NOUN
dti-1313	33	15	.	.	PUNCT
dti-1313	34	1	the	the	DET
dti-1313	34	2	sinomenine	sinomenine	NOUN
dti-1313	34	3	content	content	NOUN
dti-1313	34	4	in	in	ADP
dti-1313	34	5	sinomenine	sinomenine	NOUN
dti-1313	34	6	acutum	acutum	NOUN
dti-1313	34	7	is	be	AUX
dti-1313	34	8	1.63	1.63	NUM
dti-1313	34	9	±	±	NUM
dti-1313	34	10	0.64	0.64	NUM
dti-1313	34	11	(	(	PUNCT
dti-1313	34	12	%	%	INTJ
dti-1313	34	13	,	,	PUNCT
dti-1313	34	14	w	w	PROPN
dti-1313	34	15	/	/	SYM
dti-1313	34	16	w	w	NOUN
dti-1313	34	17	)	)	PUNCT
dti-1313	34	18	in	in	ADP
dti-1313	34	19	large	large	ADJ
dti-1313	34	20	(	(	PUNCT
dti-1313	34	21	>	>	SYM
dti-1313	34	22	3	3	NUM
dti-1313	34	23	cm	cm	NOUN
dti-1313	34	24	)	)	PUNCT
dti-1313	34	25	stem	stem	NOUN
dti-1313	34	26	,	,	PUNCT
dti-1313	34	27	0.96	0.96	NUM
dti-1313	34	28	±	±	NUM
dti-1313	34	29	0.45	0.45	NUM
dti-1313	34	30	(	(	PUNCT
dti-1313	34	31	%	%	INTJ
dti-1313	34	32	,	,	PUNCT
dti-1313	34	33	w	w	PROPN
dti-1313	34	34	/	/	SYM
dti-1313	34	35	w	w	NOUN
dti-1313	34	36	)	)	PUNCT
dti-1313	34	37	in	in	ADP
dti-1313	34	38	1–3	1–3	NUM
dti-1313	34	39	cm	cm	NOUN
dti-1313	34	40	stem	stem	NOUN
dti-1313	34	41	,	,	PUNCT
dti-1313	34	42	and	and	CCONJ
dti-1313	34	43	0.49	0.49	NUM
dti-1313	34	44	±	±	NUM
dti-1313	34	45	0.16	0.16	NUM
dti-1313	35	1	(	(	PUNCT
dti-1313	35	2	%	%	INTJ
dti-1313	35	3	,	,	PUNCT
dti-1313	35	4	w	w	PROPN
dti-1313	35	5	/	/	SYM
dti-1313	35	6	w	w	NOUN
dti-1313	35	7	)	)	PUNCT
dti-1313	35	8	in	in	ADP
dti-1313	35	9	<	<	X
dti-1313	35	10	1	1	NUM
dti-1313	35	11	cm	cm	NOUN
dti-1313	35	12	stem	stem	NOUN
dti-1313	35	13	(	(	PUNCT
dti-1313	35	14	zhao	zhao	PROPN
dti-1313	35	15	et	et	PROPN
dti-1313	35	16	al	al	PROPN
dti-1313	35	17	.	.	PROPN
dti-1313	35	18	2005	2005	NUM
dti-1313	35	19	)	)	PUNCT
dti-1313	35	20	.	.	PUNCT
dti-1313	36	1	pharmacokinetics	pharmacokinetic	NOUN
dti-1313	36	2	of	of	ADP
dti-1313	36	3	sinomenine	sinomenine	NOUN
dti-1313	36	4	the	the	DET
dti-1313	36	5	pharmacokinetics	pharmacokinetic	NOUN
dti-1313	36	6	and	and	CCONJ
dti-1313	36	7	tissue	tissue	NOUN
dti-1313	36	8	distribution	distribution	NOUN
dti-1313	36	9	of	of	ADP
dti-1313	36	10	sinomenine	sinomenine	NOUN
dti-1313	36	11	have	have	AUX
dti-1313	36	12	been	be	AUX
dti-1313	36	13	studied	study	VERB
dti-1313	36	14	in	in	ADP
dti-1313	36	15	rats	rat	NOUN
dti-1313	36	16	(	(	PUNCT
dti-1313	36	17	liu	liu	PROPN
dti-1313	36	18	et	et	PROPN
dti-1313	36	19	al	al	PROPN
dti-1313	36	20	.	.	PROPN
dti-1313	36	21	2005	2005	NUM
dti-1313	36	22	)	)	PUNCT
dti-1313	36	23	.	.	PUNCT
dti-1313	37	1	sinomenine	sinomenine	NOUN
dti-1313	37	2	achieves	achieve	VERB
dti-1313	37	3	high	high	ADJ
dti-1313	37	4	bioavilability	bioavilability	NOUN
dti-1313	37	5	(	(	PUNCT
dti-1313	37	6	about	about	ADP
dti-1313	37	7	80	80	NUM
dti-1313	37	8	%	%	NOUN
dti-1313	37	9	)	)	PUNCT
dti-1313	37	10	by	by	ADP
dti-1313	37	11	oral	oral	ADJ
dti-1313	37	12	administration	administration	NOUN
dti-1313	37	13	of	of	ADP
dti-1313	37	14	90	90	NUM
dti-1313	37	15	mg	mg	PROPN
dti-1313	37	16	/	/	SYM
dti-1313	37	17	kg	kg	PROPN
dti-1313	37	18	.	.	PUNCT
dti-1313	38	1	at	at	ADP
dti-1313	38	2	45min	45min	NOUN
dti-1313	38	3	later	later	ADV
dti-1313	38	4	,	,	PUNCT
dti-1313	38	5	sinomenine	sinomenine	NOUN
dti-1313	38	6	is	be	AUX
dti-1313	38	7	found	find	VERB
dti-1313	38	8	widely	widely	ADV
dti-1313	38	9	in	in	ADP
dti-1313	38	10	internal	internal	ADJ
dti-1313	38	11	organs	organ	NOUN
dti-1313	38	12	such	such	ADJ
dti-1313	38	13	as	as	ADP
dti-1313	38	14	kidney	kidney	NOUN
dti-1313	38	15	,	,	PUNCT
dti-1313	38	16	liver	liver	NOUN
dti-1313	38	17	,	,	PUNCT
dti-1313	38	18	lung	lung	NOUN
dti-1313	38	19	,	,	PUNCT
dti-1313	38	20	spleen	spleen	NOUN
dti-1313	38	21	,	,	PUNCT
dti-1313	38	22	heart	heart	NOUN
dti-1313	38	23	,	,	PUNCT
dti-1313	38	24	brain	brain	NOUN
dti-1313	38	25	and	and	CCONJ
dti-1313	38	26	testis	testis	PROPN
dti-1313	38	27	.	.	PUNCT
dti-1313	39	1	sinomenine	sinomenine	NOUN
dti-1313	39	2	is	be	AUX
dti-1313	39	3	metabolized	metabolize	VERB
dti-1313	39	4	and	and	CCONJ
dti-1313	39	5	eliminated	eliminate	VERB
dti-1313	39	6	by	by	ADP
dti-1313	39	7	kidney	kidney	NOUN
dti-1313	39	8	and	and	CCONJ
dti-1313	39	9	liver	liver	NOUN
dti-1313	39	10	.	.	PUNCT
dti-1313	40	1	tmax	tmax	ADV
dti-1313	40	2	is	be	AUX
dti-1313	40	3	39.5	39.5	NUM
dti-1313	40	4	±	±	NUM
dti-1313	40	5	8.49	8.49	NUM
dti-1313	40	6	min	min	NOUN
dti-1313	40	7	,	,	PUNCT
dti-1313	40	8	cmax	cmax	NOUN
dti-1313	40	9	is	be	AUX
dti-1313	40	10	13.89	13.89	NUM
dti-1313	40	11	±	±	NUM
dti-1313	40	12	4.29	4.29	NUM
dti-1313	40	13	µg	µg	NOUN
dti-1313	40	14	/	/	SYM
dti-1313	40	15	ml	ml	NOUN
dti-1313	40	16	,	,	PUNCT
dti-1313	40	17	t1/2a	t1/2a	NOUN
dti-1313	40	18	phase	phase	NOUN
dti-1313	40	19	is	be	AUX
dti-1313	40	20	61.28	61.28	NUM
dti-1313	40	21	±	±	NUM
dti-1313	40	22	53.62	53.62	NUM
dti-1313	40	23	min	min	NOUN
dti-1313	40	24	,	,	PUNCT
dti-1313	40	25	auc0	auc0	PROPN
dti-1313	40	26	-	-	PUNCT
dti-1313	40	27	t	t	PROPN
dti-1313	40	28	is	be	AUX
dti-1313	40	29	2331.53	2331.53	NUM
dti-1313	40	30	±	±	NUM
dti-1313	40	31	1172.77	1172.77	NUM
dti-1313	40	32	µg	µg	NOUN
dti-1313	40	33	-	-	PUNCT
dti-1313	40	34	min	min	NOUN
dti-1313	40	35	/	/	SYM
dti-1313	40	36	ml	ml	NOUN
dti-1313	40	37	,	,	PUNCT
dti-1313	40	38	and	and	CCONJ
dti-1313	40	39	cl	cl	NOUN
dti-1313	40	40	is	be	AUX
dti-1313	40	41	42.95	42.95	NUM
dti-1313	40	42	±	±	NUM
dti-1313	40	43	14.4	14.4	NUM
dti-1313	40	44	ml	ml	NOUN
dti-1313	40	45	/	/	SYM
dti-1313	40	46	min	min	NOUN
dti-1313	40	47	per	per	ADP
dti-1313	40	48	kg	kg	X
dti-1313	40	49	.	.	PUNCT
dti-1313	41	1	in	in	ADP
dti-1313	41	2	clinical	clinical	ADJ
dti-1313	41	3	studies	study	NOUN
dti-1313	41	4	,	,	PUNCT
dti-1313	41	5	oral	oral	ADJ
dti-1313	41	6	administration	administration	NOUN
dti-1313	41	7	of	of	ADP
dti-1313	41	8	80	80	NUM
dti-1313	41	9	mg	mg	PROPN
dti-1313	41	10	sinomenine	sinomenine	NOUN
dti-1313	41	11	is	be	AUX
dti-1313	41	12	performed	perform	VERB
dti-1313	41	13	for	for	ADP
dti-1313	41	14	healthy	healthy	ADJ
dti-1313	41	15	volunteers	volunteer	NOUN
dti-1313	41	16	(	(	PUNCT
dti-1313	41	17	yan	yan	PROPN
dti-1313	41	18	et	et	PROPN
dti-1313	41	19	al	al	PROPN
dti-1313	41	20	.	.	PROPN
dti-1313	41	21	1997	1997	NUM
dti-1313	41	22	)	)	PUNCT
dti-1313	41	23	.	.	PUNCT
dti-1313	42	1	in	in	ADP
dti-1313	42	2	the	the	DET
dti-1313	42	3	pharmacokinetic	pharmacokinetic	ADJ
dti-1313	42	4	parameters	parameter	NOUN
dti-1313	42	5	,	,	PUNCT
dti-1313	42	6	t1/2α	t1/2α	PROPN
dti-1313	42	7	is	be	AUX
dti-1313	42	8	1.04	1.04	NUM
dti-1313	42	9	±	±	NUM
dti-1313	42	10	0.491h	0.491h	NOUN
dti-1313	42	11	,	,	PUNCT
dti-1313	42	12	t1/2β	t1/2β	PROPN
dti-1313	42	13	is	be	AUX
dti-1313	42	14	9.397	9.397	NUM
dti-1313	42	15	±	±	NUM
dti-1313	42	16	2.425h	2.425h	NUM
dti-1313	42	17	,	,	PUNCT
dti-1313	42	18	tmax	tmax	ADV
dti-1313	42	19	is	be	AUX
dti-1313	42	20	1.04	1.04	NUM
dti-1313	42	21	±	±	NUM
dti-1313	42	22	0.274h	0.274h	NOUN
dti-1313	42	23	,	,	PUNCT
dti-1313	42	24	cmax	cmax	NOUN
dti-1313	42	25	is	be	AUX
dti-1313	42	26	246.6	246.6	NUM
dti-1313	42	27	±	±	NUM
dti-1313	42	28	71.165	71.165	NUM
dti-1313	42	29	ng	ng	PROPN
dti-1313	42	30	/	/	SYM
dti-1313	42	31	ml	ml	PROPN
dti-1313	42	32	.	.	PUNCT
dti-1313	43	1	furthermore	furthermore	ADV
dti-1313	43	2	,	,	PUNCT
dti-1313	43	3	auc	auc	PRON
dti-1313	43	4	is	be	AUX
dti-1313	43	5	2651.158	2651.158	NUM
dti-1313	43	6	±	±	NUM
dti-1313	43	7	1039.050	1039.050	PROPN
dti-1313	43	8	ng.h	ng.h	NOUN
dti-1313	43	9	/	/	SYM
dti-1313	43	10	ml	ml	NOUN
dti-1313	43	11	,	,	PUNCT
dti-1313	43	12	and	and	CCONJ
dti-1313	43	13	cl	cl	NOUN
dti-1313	43	14	is	be	AUX
dti-1313	43	15	0.033	0.033	NUM
dti-1313	43	16	±	±	NUM
dti-1313	43	17	0.010	0.010	NUM
dti-1313	43	18	ng	ng	PROPN
dti-1313	43	19	/	/	SYM
dti-1313	43	20	ml	ml	NOUN
dti-1313	43	21	.	.	PUNCT
dti-1313	44	1	vascular	vascular	ADJ
dti-1313	44	2	pharmacology	pharmacology	NOUN
dti-1313	44	3	male	male	NOUN
dti-1313	44	4	wistar	wistar	PROPN
dti-1313	44	5	rats	rat	NOUN
dti-1313	44	6	(	(	PUNCT
dti-1313	44	7	5–10	5–10	ADJ
dti-1313	44	8	week	week	NOUN
dti-1313	44	9	-	-	PUNCT
dti-1313	44	10	old	old	ADJ
dti-1313	44	11	)	)	PUNCT
dti-1313	44	12	were	be	AUX
dti-1313	44	13	anesthetized	anesthetize	VERB
dti-1313	44	14	with	with	ADP
dti-1313	44	15	ether	ether	NOUN
dti-1313	44	16	,	,	PUNCT
dti-1313	44	17	and	and	CCONJ
dti-1313	44	18	euthanized	euthanize	VERB
dti-1313	44	19	by	by	ADP
dti-1313	44	20	exsanguination	exsanguination	NOUN
dti-1313	44	21	.	.	PUNCT
dti-1313	45	1	the	the	DET
dti-1313	45	2	thoracic	thoracic	NOUN
dti-1313	45	3	aorta	aorta	NOUN
dti-1313	45	4	was	be	AUX
dti-1313	45	5	quickly	quickly	ADV
dti-1313	45	6	removed	remove	VERB
dti-1313	45	7	,	,	PUNCT
dti-1313	45	8	and	and	CCONJ
dti-1313	45	9	then	then	ADV
dti-1313	45	10	the	the	DET
dti-1313	45	11	isolated	isolated	ADJ
dti-1313	45	12	aorta	aorta	NOUN
dti-1313	45	13	was	be	AUX
dti-1313	45	14	cut	cut	VERB
dti-1313	45	15	into	into	ADP
dti-1313	45	16	rings	ring	NOUN
dti-1313	45	17	of	of	ADP
dti-1313	45	18	3	3	NUM
dti-1313	45	19	-	-	PUNCT
dti-1313	45	20	mm	mm	NOUN
dti-1313	45	21	in	in	ADP
dti-1313	45	22	length	length	NOUN
dti-1313	45	23	.	.	PUNCT
dti-1313	46	1	all	all	DET
dti-1313	46	2	rings	ring	NOUN
dti-1313	46	3	were	be	AUX
dti-1313	46	4	stretched	stretch	VERB
dti-1313	46	5	to	to	PART
dti-1313	46	6	generate	generate	VERB
dti-1313	46	7	a	a	DET
dti-1313	46	8	resting	rest	VERB
dti-1313	46	9	tension	tension	NOUN
dti-1313	46	10	of	of	ADP
dti-1313	46	11	1.2	1.2	NUM
dti-1313	46	12	g	g	NOUN
dti-1313	46	13	in	in	ADP
dti-1313	46	14	krebs	krebs	NOUN
dti-1313	46	15	solution	solution	NOUN
dti-1313	46	16	.	.	PUNCT
dti-1313	47	1	after	after	ADP
dti-1313	47	2	40	40	NUM
dti-1313	47	3	min	min	NOUN
dti-1313	47	4	of	of	ADP
dti-1313	47	5	resting	resting	NOUN
dti-1313	47	6	,	,	PUNCT
dti-1313	47	7	norepinephrine	norepinephrine	NOUN
dti-1313	47	8	(	(	PUNCT
dti-1313	47	9	ne	ne	NOUN
dti-1313	47	10	)	)	PUNCT
dti-1313	47	11	(	(	PUNCT
dti-1313	47	12	5	5	NUM
dti-1313	47	13	µm	µm	NOUN
dti-1313	47	14	)	)	PUNCT
dti-1313	47	15	was	be	AUX
dti-1313	47	16	added	add	VERB
dti-1313	47	17	to	to	ADP
dti-1313	47	18	the	the	DET
dti-1313	47	19	tissue	tissue	NOUN
dti-1313	47	20	bath	bath	NOUN
dti-1313	47	21	.	.	PUNCT
dti-1313	48	1	after	after	SCONJ
dti-1313	48	2	the	the	DET
dti-1313	48	3	contractile	contractile	ADJ
dti-1313	48	4	response	response	NOUN
dti-1313	48	5	became	become	VERB
dti-1313	48	6	steady	steady	ADJ
dti-1313	48	7	,	,	PUNCT
dti-1313	48	8	the	the	DET
dti-1313	48	9	drugs	drug	NOUN
dti-1313	48	10	were	be	AUX
dti-1313	48	11	cumulatively	cumulatively	ADV
dti-1313	48	12	administrated	administrate	VERB
dti-1313	48	13	into	into	ADP
dti-1313	48	14	the	the	DET
dti-1313	48	15	bath	bath	NOUN
dti-1313	48	16	solution	solution	NOUN
dti-1313	48	17	.	.	PUNCT
dti-1313	49	1	the	the	DET
dti-1313	49	2	similar	similar	ADJ
dti-1313	49	3	methods	method	NOUN
dti-1313	49	4	are	be	AUX
dti-1313	49	5	described	describe	VERB
dti-1313	49	6	in	in	ADP
dti-1313	49	7	our	our	PRON
dti-1313	49	8	previous	previous	ADJ
dti-1313	49	9	reports	report	NOUN
dti-1313	49	10	(	(	PUNCT
dti-1313	49	11	nishida	nishida	NOUN
dti-1313	49	12	and	and	CCONJ
dti-1313	49	13	satoh	satoh	NOUN
dti-1313	49	14	,	,	PUNCT
dti-1313	49	15	2003	2003	NUM
dti-1313	49	16	;	;	PUNCT
dti-1313	49	17	2006	2006	NUM
dti-1313	49	18	)	)	PUNCT
dti-1313	49	19	.	.	PUNCT
dti-1313	50	1	the	the	DET
dti-1313	50	2	aorta	aorta	NOUN
dti-1313	50	3	ring	ring	NOUN
dti-1313	50	4	strip	strip	PROPN
dti-1313	50	5	of	of	ADP
dti-1313	50	6	rat	rat	NOUN
dti-1313	50	7	had	have	VERB
dti-1313	50	8	a	a	DET
dti-1313	50	9	strong	strong	ADJ
dti-1313	50	10	contraction	contraction	NOUN
dti-1313	50	11	after	after	ADP
dti-1313	50	12	an	an	DET
dti-1313	50	13	initial	initial	ADJ
dti-1313	50	14	application	application	NOUN
dti-1313	50	15	of	of	ADP
dti-1313	50	16	5	5	NUM
dti-1313	50	17	µm	µm	SYM
dti-1313	50	18	ne	ne	PROPN
dti-1313	50	19	.	.	PROPN
dti-1313	50	20	sinomenine	sinomenine	NOUN
dti-1313	50	21	(	(	PUNCT
dti-1313	50	22	0.1	0.1	NUM
dti-1313	50	23	to	to	PART
dti-1313	50	24	100	100	NUM
dti-1313	50	25	µm	µm	NOUN
dti-1313	50	26	)	)	PUNCT
dti-1313	50	27	applications	application	NOUN
dti-1313	50	28	potently	potently	ADV
dti-1313	50	29	relaxed	relax	VERB
dti-1313	50	30	the	the	DET
dti-1313	50	31	contraction	contraction	NOUN
dti-1313	50	32	induced	induce	VERB
dti-1313	50	33	by	by	ADP
dti-1313	50	34	ne	ne	PROPN
dti-1313	50	35	in	in	ADP
dti-1313	50	36	a	a	DET
dti-1313	50	37	concentration	concentration	NOUN
dti-1313	50	38	-	-	PUNCT
dti-1313	50	39	dependent	dependent	ADJ
dti-1313	50	40	manner	manner	NOUN
dti-1313	50	41	(	(	PUNCT
dti-1313	50	42	nishida	nishida	NOUN
dti-1313	50	43	and	and	CCONJ
dti-1313	50	44	satoh	satoh	NOUN
dti-1313	50	45	,	,	PUNCT
dti-1313	50	46	2006	2006	NUM
dti-1313	50	47	)	)	PUNCT
dti-1313	50	48	.	.	PUNCT
dti-1313	51	1	the	the	DET
dti-1313	51	2	relaxation	relaxation	NOUN
dti-1313	51	3	was	be	AUX
dti-1313	51	4	produced	produce	VERB
dti-1313	51	5	at	at	ADP
dti-1313	51	6	the	the	DET
dti-1313	51	7	concentrations	concentration	NOUN
dti-1313	51	8	of	of	ADP
dti-1313	51	9	over	over	ADP
dti-1313	51	10	0.3	0.3	NUM
dti-1313	51	11	µm	µm	NOUN
dti-1313	51	12	sinomenine	sinomenine	NOUN
dti-1313	51	13	,	,	PUNCT
dti-1313	51	14	and	and	CCONJ
dti-1313	51	15	at	at	ADP
dti-1313	51	16	100	100	NUM
dti-1313	51	17	µm	µm	NUM
dti-1313	51	18	decreased	decrease	VERB
dti-1313	51	19	the	the	DET
dti-1313	51	20	contractions	contraction	NOUN
dti-1313	51	21	by	by	ADP
dti-1313	51	22	68.8	68.8	NUM
dti-1313	51	23	±	±	NUM
dti-1313	51	24	5.1	5.1	NUM
dti-1313	51	25	%	%	NOUN
dti-1313	51	26	(	(	PUNCT
dti-1313	51	27	n	n	NOUN
dti-1313	51	28	=	=	SYM
dti-1313	51	29	6	6	NUM
dti-1313	51	30	,	,	PUNCT
dti-1313	51	31	p	p	X
dti-1313	51	32	<	<	X
dti-1313	51	33	0.001	0.001	NUM
dti-1313	51	34	)	)	PUNCT
dti-1313	51	35	.	.	PUNCT
dti-1313	52	1	pdb	pdb	PROPN
dti-1313	52	2	(	(	PUNCT
dti-1313	52	3	300	300	NUM
dti-1313	52	4	nm	nm	NOUN
dti-1313	52	5	)	)	PUNCT
dti-1313	52	6	and	and	CCONJ
dti-1313	52	7	kcl	kcl	PROPN
dti-1313	52	8	(	(	PUNCT
dti-1313	52	9	60	60	NUM
dti-1313	52	10	mm	mm	NOUN
dti-1313	52	11	)	)	PUNCT
dti-1313	52	12	also	also	ADV
dti-1313	52	13	caused	cause	VERB
dti-1313	52	14	strong	strong	ADJ
dti-1313	52	15	contractions	contraction	NOUN
dti-1313	52	16	.	.	PUNCT
dti-1313	53	1	sinomenine	sinomenine	NOUN
dti-1313	53	2	dilated	dilate	VERB
dti-1313	53	3	both	both	CCONJ
dti-1313	53	4	pdband	pdband	NOUN
dti-1313	53	5	kcl	kcl	NOUN
dti-1313	53	6	-	-	PUNCT
dti-1313	53	7	induced	induce	VERB
dti-1313	53	8	contractions	contraction	NOUN
dti-1313	53	9	in	in	ADP
dti-1313	53	10	a	a	DET
dti-1313	53	11	concentration	concentration	NOUN
dti-1313	53	12	-	-	PUNCT
dti-1313	53	13	dependent	dependent	ADJ
dti-1313	53	14	manner	manner	NOUN
dti-1313	53	15	;	;	PUNCT
dti-1313	53	16	at	at	ADP
dti-1313	53	17	100	100	NUM
dti-1313	53	18	µm	µm	ADP
dti-1313	53	19	by	by	ADP
dti-1313	53	20	49.9	49.9	NUM
dti-1313	53	21	±	±	NUM
dti-1313	53	22	9.8	9.8	NUM
dti-1313	53	23	%	%	NOUN
dti-1313	53	24	(	(	PUNCT
dti-1313	53	25	n	n	NOUN
dti-1313	53	26	=	=	SYM
dti-1313	53	27	6	6	NUM
dti-1313	53	28	,	,	PUNCT
dti-1313	53	29	p	p	X
dti-1313	53	30	<	<	X
dti-1313	53	31	0.001	0.001	NUM
dti-1313	53	32	)	)	PUNCT
dti-1313	53	33	and	and	CCONJ
dti-1313	53	34	86.9	86.9	NUM
dti-1313	53	35	±	±	NUM
dti-1313	53	36	8.5	8.5	NUM
dti-1313	53	37	%	%	NOUN
dti-1313	53	38	(	(	PUNCT
dti-1313	53	39	n	n	NOUN
dti-1313	53	40	=	=	SYM
dti-1313	53	41	6	6	NUM
dti-1313	53	42	,	,	PUNCT
dti-1313	53	43	p	p	X
dti-1313	53	44	<	<	X
dti-1313	53	45	0.001	0.001	NUM
dti-1313	53	46	)	)	PUNCT
dti-1313	53	47	,	,	PUNCT
dti-1313	53	48	respectively	respectively	ADV
dti-1313	53	49	(	(	PUNCT
dti-1313	53	50	fig	fig	NOUN
dti-1313	53	51	.	.	NOUN
dti-1313	53	52	1	1	NUM
dti-1313	53	53	)	)	PUNCT
dti-1313	53	54	.	.	PUNCT
dti-1313	54	1	furthermore	furthermore	ADV
dti-1313	54	2	,	,	PUNCT
dti-1313	54	3	the	the	DET
dti-1313	54	4	relaxation	relaxation	NOUN
dti-1313	54	5	of	of	ADP
dti-1313	54	6	sinomenine	sinomenine	NOUN
dti-1313	54	7	(	(	PUNCT
dti-1313	54	8	0.1	0.1	NUM
dti-1313	54	9	to	to	PART
dti-1313	54	10	100	100	NUM
dti-1313	54	11	µm	µm	NOUN
dti-1313	54	12	)	)	PUNCT
dti-1313	54	13	was	be	AUX
dti-1313	54	14	attenuated	attenuate	VERB
dti-1313	54	15	signifi	signifi	NOUN
dti-1313	54	16	cantly	cantly	ADV
dti-1313	54	17	by	by	ADP
dti-1313	54	18	the	the	DET
dti-1313	54	19	pretreatment	pretreatment	NOUN
dti-1313	54	20	with	with	ADP
dti-1313	54	21	nicardipine	nicardipine	PROPN
dti-1313	54	22	(	(	PUNCT
dti-1313	54	23	fig	fig	NOUN
dti-1313	54	24	.	.	PUNCT
dti-1313	55	1	2	2	NUM
dti-1313	55	2	)	)	PUNCT
dti-1313	55	3	.	.	PUNCT
dti-1313	56	1	at	at	ADP
dti-1313	56	2	100	100	NUM
dti-1313	56	3	µm	µm	ADP
dti-1313	56	4	the	the	DET
dti-1313	56	5	relaxation	relaxation	NOUN
dti-1313	56	6	decreased	decrease	VERB
dti-1313	56	7	from	from	ADP
dti-1313	56	8	68.8	68.8	NUM
dti-1313	56	9	±	±	NUM
dti-1313	56	10	5.1	5.1	NUM
dti-1313	56	11	%	%	NOUN
dti-1313	56	12	(	(	PUNCT
dti-1313	56	13	n	n	NOUN
dti-1313	56	14	=	=	SYM
dti-1313	56	15	6	6	NUM
dti-1313	56	16	)	)	PUNCT
dti-1313	56	17	to	to	ADP
dti-1313	56	18	35.5	35.5	NUM
dti-1313	56	19	±	±	NUM
dti-1313	56	20	6.9	6.9	NUM
dti-1313	56	21	%	%	NOUN
dti-1313	56	22	(	(	PUNCT
dti-1313	56	23	n	n	NOUN
dti-1313	56	24	=	=	SYM
dti-1313	56	25	5	5	NUM
dti-1313	56	26	,	,	PUNCT
dti-1313	56	27	p	p	X
dti-1313	56	28	<	<	X
dti-1313	56	29	0.001	0.001	NUM
dti-1313	56	30	)	)	PUNCT
dti-1313	56	31	.	.	PUNCT
dti-1313	57	1	since	since	SCONJ
dti-1313	57	2	pk	pk	NOUN
dti-1313	57	3	-	-	NOUN
dti-1313	57	4	c	c	NOUN
dti-1313	57	5	inhibition	inhibition	NOUN
dti-1313	57	6	may	may	AUX
dti-1313	57	7	be	be	AUX
dti-1313	57	8	related	relate	VERB
dti-1313	57	9	to	to	ADP
dti-1313	57	10	sinomenine	sinomenine	NOUN
dti-1313	57	11	-	-	PUNCT
dti-1313	57	12	induced	induce	VERB
dti-1313	57	13	vasorelaxation	vasorelaxation	NOUN
dti-1313	57	14	,	,	PUNCT
dti-1313	57	15	the	the	DET
dti-1313	57	16	pretreatment	pretreatment	NOUN
dti-1313	57	17	with	with	ADP
dti-1313	57	18	staurosporine	staurosporine	NOUN
dti-1313	57	19	(	(	PUNCT
dti-1313	57	20	30	30	NUM
dti-1313	57	21	nm	nm	NOUN
dti-1313	57	22	)	)	PUNCT
dti-1313	57	23	for	for	ADP
dti-1313	57	24	30	30	NUM
dti-1313	57	25	min	min	NOUN
dti-1313	57	26	was	be	AUX
dti-1313	57	27	carried	carry	VERB
dti-1313	57	28	out	out	ADP
dti-1313	57	29	(	(	PUNCT
dti-1313	57	30	satoh	satoh	NOUN
dti-1313	57	31	,	,	PUNCT
dti-1313	57	32	1996	1996	NUM
dti-1313	57	33	;	;	PUNCT
dti-1313	57	34	nishida	nishida	NOUN
dti-1313	57	35	and	and	CCONJ
dti-1313	57	36	satoh	satoh	NOUN
dti-1313	57	37	,	,	PUNCT
dti-1313	57	38	2004	2004	NUM
dti-1313	57	39	)	)	PUNCT
dti-1313	57	40	.	.	PUNCT
dti-1313	58	1	staurosporine	staurosporine	PROPN
dti-1313	58	2	attenuated	attenuate	VERB
dti-1313	58	3	the	the	DET
dti-1313	58	4	sinomenine	sinomenine	NOUN
dti-1313	58	5	-	-	PUNCT
dti-1313	58	6	induced	induce	VERB
dti-1313	58	7	vasorelaxation	vasorelaxation	NOUN
dti-1313	58	8	;	;	PUNCT
dti-1313	58	9	at	at	ADP
dti-1313	58	10	100	100	NUM
dti-1313	58	11	µm	µm	NOUN
dti-1313	58	12	from	from	ADP
dti-1313	58	13	68.8	68.8	NUM
dti-1313	58	14	±	±	NUM
dti-1313	58	15	5.1	5.1	NUM
dti-1313	58	16	%	%	NOUN
dti-1313	58	17	(	(	PUNCT
dti-1313	58	18	n	n	NOUN
dti-1313	58	19	=	=	SYM
dti-1313	58	20	6	6	NUM
dti-1313	58	21	)	)	PUNCT
dti-1313	58	22	to	to	ADP
dti-1313	58	23	49.5	49.5	NUM
dti-1313	58	24	±	±	NUM
dti-1313	58	25	7.7	7.7	NUM
dti-1313	58	26	%	%	NOUN
dti-1313	58	27	(	(	PUNCT
dti-1313	58	28	n	n	NOUN
dti-1313	58	29	=	=	SYM
dti-1313	58	30	5	5	NUM
dti-1313	58	31	,	,	PUNCT
dti-1313	58	32	p	p	X
dti-1313	58	33	<	<	X
dti-1313	58	34	0.001	0.001	NUM
dti-1313	58	35	)	)	PUNCT
dti-1313	58	36	(	(	PUNCT
dti-1313	58	37	fig	fig	NOUN
dti-1313	58	38	.	.	PUNCT
dti-1313	59	1	2	2	NUM
dti-1313	59	2	)	)	PUNCT
dti-1313	59	3	.	.	PUNCT
dti-1313	60	1	in	in	ADP
dti-1313	60	2	addition	addition	NOUN
dti-1313	60	3	,	,	PUNCT
dti-1313	60	4	propranolol	propranolol	PROPN
dti-1313	60	5	(	(	PUNCT
dti-1313	60	6	0.3	0.3	NUM
dti-1313	60	7	µm	µm	NOUN
dti-1313	60	8	)	)	PUNCT
dti-1313	60	9	also	also	ADV
dti-1313	60	10	signifi	signifi	VERB
dti-1313	60	11	cantly	cantly	ADV
dti-1313	60	12	attenuated	attenuate	VERB
dti-1313	60	13	the	the	DET
dti-1313	60	14	sinomenineinduced	sinomenineinduced	ADJ
dti-1313	60	15	relaxation	relaxation	NOUN
dti-1313	60	16	.	.	PUNCT
dti-1313	61	1	the	the	DET
dti-1313	61	2	vasorelaxation	vasorelaxation	NOUN
dti-1313	61	3	at	at	ADP
dti-1313	61	4	100	100	NUM
dti-1313	61	5	µm	µm	NOUN
dti-1313	61	6	sinomenine	sinomenine	NOUN
dti-1313	61	7	was	be	AUX
dti-1313	61	8	attenuated	attenuate	VERB
dti-1313	61	9	to	to	ADP
dti-1313	61	10	45.2	45.2	NUM
dti-1313	61	11	±	±	NUM
dti-1313	61	12	4.2	4.2	NUM
dti-1313	61	13	%	%	NOUN
dti-1313	61	14	(	(	PUNCT
dti-1313	61	15	n	n	NOUN
dti-1313	61	16	=	=	SYM
dti-1313	61	17	5	5	NUM
dti-1313	61	18	,	,	PUNCT
dti-1313	61	19	p	p	X
dti-1313	61	20	<	<	X
dti-1313	61	21	0.01	0.01	NUM
dti-1313	61	22	)	)	PUNCT
dti-1313	61	23	.	.	PUNCT
dti-1313	62	1	therefore	therefore	ADV
dti-1313	62	2	,	,	PUNCT
dti-1313	62	3	the	the	DET
dti-1313	62	4	modulation	modulation	NOUN
dti-1313	62	5	of	of	ADP
dti-1313	62	6	both	both	PRON
dti-1313	62	7	ca2	ca2	PROPN
dti-1313	62	8	+	+	PROPN
dti-1313	62	9	channel	channel	NOUN
dti-1313	62	10	and	and	CCONJ
dti-1313	62	11	pk	pk	NOUN
dti-1313	62	12	-	-	NOUN
dti-1313	62	13	c	c	NOUN
dti-1313	62	14	is	be	AUX
dti-1313	62	15	largely	largely	ADV
dti-1313	62	16	contributed	contribute	VERB
dti-1313	62	17	to	to	ADP
dti-1313	62	18	sinomenineinduced	sinomenineinduced	ADJ
dti-1313	62	19	actions	action	NOUN
dti-1313	62	20	,	,	PUNCT
dti-1313	62	21	and	and	CCONJ
dti-1313	62	22	sinomenine	sinomenine	NOUN
dti-1313	62	23	also	also	ADV
dti-1313	62	24	vasodilates	vasodilate	VERB
dti-1313	62	25	mediated	mediate	VERB
dti-1313	62	26	through	through	ADP
dti-1313	62	27	β	β	ADJ
dti-1313	62	28	-	-	PUNCT
dti-1313	62	29	adrenoceptor	adrenoceptor	NOUN
dti-1313	62	30	stimulation	stimulation	NOUN
dti-1313	62	31	of	of	ADP
dti-1313	62	32	aortic	aortic	ADJ
dti-1313	62	33	smooth	smooth	ADJ
dti-1313	62	34	muscle	muscle	NOUN
dti-1313	62	35	cells	cell	NOUN
dti-1313	62	36	.	.	PUNCT
dti-1313	63	1	for	for	ADP
dti-1313	63	2	involvement	involvement	NOUN
dti-1313	63	3	with	with	ADP
dti-1313	63	4	endothelium	endothelium	NOUN
dti-1313	63	5	-	-	PUNCT
dti-1313	63	6	dependent	dependent	ADJ
dti-1313	63	7	relaxation	relaxation	NOUN
dti-1313	63	8	via	via	ADP
dti-1313	63	9	no	no	DET
dti-1313	63	10	activation	activation	NOUN
dti-1313	63	11	,	,	PUNCT
dti-1313	63	12	a	a	DET
dti-1313	63	13	pretreatment	pretreatment	NOUN
dti-1313	63	14	with	with	ADP
dti-1313	63	15	100	100	NUM
dti-1313	63	16	µm	µm	ADP
dti-1313	63	17	l	l	NOUN
dti-1313	63	18	-	-	PROPN
dti-1313	63	19	nmma	nmma	PROPN
dti-1313	63	20	(	(	PUNCT
dti-1313	63	21	a	a	DET
dti-1313	63	22	non	non	ADJ
dti-1313	63	23	-	-	ADJ
dti-1313	63	24	selective	selective	ADJ
dti-1313	63	25	no	no	DET
dti-1313	63	26	synthesis	synthesis	NOUN
dti-1313	63	27	inhibitor	inhibitor	NOUN
dti-1313	63	28	)	)	PUNCT
dti-1313	63	29	was	be	AUX
dti-1313	63	30	carried	carry	VERB
dti-1313	63	31	out	out	ADP
dti-1313	63	32	(	(	PUNCT
dti-1313	63	33	nishida	nishida	NOUN
dti-1313	63	34	and	and	CCONJ
dti-1313	63	35	satoh	satoh	NOUN
dti-1313	63	36	,	,	PUNCT
dti-1313	63	37	2003	2003	NUM
dti-1313	63	38	;	;	PUNCT
dti-1313	63	39	2007	2007	NUM
dti-1313	63	40	)	)	PUNCT
dti-1313	63	41	.	.	PUNCT
dti-1313	64	1	under	under	ADP
dti-1313	64	2	the	the	DET
dti-1313	64	3	conditions	condition	NOUN
dti-1313	64	4	,	,	PUNCT
dti-1313	64	5	the	the	DET
dti-1313	64	6	vasorelaxation	vasorelaxation	NOUN
dti-1313	64	7	induced	induce	VERB
dti-1313	64	8	by	by	ADP
dti-1313	64	9	sinomenine	sinomenine	NOUN
dti-1313	64	10	was	be	AUX
dti-1313	64	11	attenuated	attenuate	VERB
dti-1313	64	12	from	from	ADP
dti-1313	64	13	68.8	68.8	NUM
dti-1313	64	14	±	±	NUM
dti-1313	64	15	5.1	5.1	NUM
dti-1313	64	16	%	%	NOUN
dti-1313	64	17	(	(	PUNCT
dti-1313	64	18	n	n	NOUN
dti-1313	64	19	=	=	SYM
dti-1313	64	20	6	6	NUM
dti-1313	64	21	)	)	PUNCT
dti-1313	64	22	to	to	ADP
dti-1313	64	23	25.3	25.3	NUM
dti-1313	64	24	±	±	NUM
dti-1313	64	25	2.3	2.3	NUM
dti-1313	64	26	%	%	NOUN
dti-1313	64	27	(	(	PUNCT
dti-1313	64	28	n	n	NOUN
dti-1313	64	29	=	=	SYM
dti-1313	64	30	5	5	NUM
dti-1313	64	31	,	,	PUNCT
dti-1313	64	32	p	p	X
dti-1313	64	33	<	<	X
dti-1313	64	34	0.01	0.01	NUM
dti-1313	64	35	)	)	PUNCT
dti-1313	64	36	(	(	PUNCT
dti-1313	64	37	fig	fig	NOUN
dti-1313	64	38	.	.	PUNCT
dti-1313	65	1	2	2	NUM
dti-1313	65	2	)	)	PUNCT
dti-1313	65	3	.	.	PUNCT
dti-1313	66	1	the	the	DET
dti-1313	66	2	attenuation	attenuation	NOUN
dti-1313	66	3	was	be	AUX
dti-1313	66	4	supported	support	VERB
dti-1313	66	5	by	by	ADP
dti-1313	66	6	the	the	DET
dti-1313	66	7	results	result	NOUN
dti-1313	66	8	using	use	VERB
dti-1313	66	9	the	the	DET
dti-1313	66	10	aorta	aorta	NOUN
dti-1313	66	11	with	with	ADP
dti-1313	66	12	removal	removal	NOUN
dti-1313	66	13	of	of	ADP
dti-1313	66	14	endothelium	endothelium	NOUN
dti-1313	66	15	;	;	PUNCT
dti-1313	66	16	at	at	ADP
dti-1313	66	17	100	100	NUM
dti-1313	66	18	µm	µm	NOUN
dti-1313	66	19	sinomenine	sinomenine	NOUN
dti-1313	66	20	by	by	ADP
dti-1313	66	21	53.7	53.7	NUM
dti-1313	66	22	±	±	NUM
dti-1313	66	23	1.8	1.8	NUM
dti-1313	66	24	%	%	NOUN
dti-1313	66	25	(	(	PUNCT
dti-1313	66	26	n	n	NOUN
dti-1313	66	27	=	=	SYM
dti-1313	66	28	5	5	NUM
dti-1313	66	29	,	,	PUNCT
dti-1313	66	30	p	p	X
dti-1313	66	31	<	<	X
dti-1313	66	32	0.01	0.01	NUM
dti-1313	66	33	)	)	PUNCT
dti-1313	66	34	.	.	PUNCT
dti-1313	67	1	indomethacin	indomethacin	PROPN
dti-1313	67	2	(	(	PUNCT
dti-1313	67	3	10	10	NUM
dti-1313	67	4	µm	µm	NOUN
dti-1313	67	5	)	)	PUNCT
dti-1313	67	6	,	,	PUNCT
dti-1313	67	7	as	as	ADP
dti-1313	67	8	an	an	DET
dti-1313	67	9	satoh	satoh	NOUN
dti-1313	67	10	et	et	NOUN
dti-1313	67	11	al.indd	al.indd	X
dti-1313	67	12	2	2	NUM
dti-1313	67	13	5/14/2007	5/14/2007	NUM
dti-1313	67	14	8:59:09	8:59:09	NUM
dti-1313	67	15	pm	pm	NOUN
dti-1313	67	16	98	98	NUM
dti-1313	67	17	cardiovascular	cardiovascular	ADJ
dti-1313	67	18	pharmacology	pharmacology	NOUN
dti-1313	67	19	of	of	ADP
dti-1313	67	20	sinomenine	sinomenine	NOUN
dti-1313	67	21	drug	drug	NOUN
dti-1313	67	22	target	target	NOUN
dti-1313	67	23	insights	insight	NOUN
dti-1313	67	24	2007	2007	NUM
dti-1313	67	25	:	:	SYM
dti-1313	67	26	2	2	NUM
dti-1313	67	27	inhibitor	inhibitor	NOUN
dti-1313	67	28	of	of	ADP
dti-1313	67	29	prostanoid	prostanoid	NOUN
dti-1313	67	30	production	production	NOUN
dti-1313	67	31	,	,	PUNCT
dti-1313	67	32	also	also	ADV
dti-1313	67	33	strongly	strongly	ADV
dti-1313	67	34	reduced	reduce	VERB
dti-1313	67	35	the	the	DET
dti-1313	67	36	vasorelaxation	vasorelaxation	NOUN
dti-1313	67	37	induced	induce	VERB
dti-1313	67	38	by	by	ADP
dti-1313	67	39	100	100	NUM
dti-1313	67	40	µm	µm	NOUN
dti-1313	67	41	sinomenine	sinomenine	NOUN
dti-1313	67	42	to	to	ADP
dti-1313	67	43	37.1	37.1	NUM
dti-1313	67	44	±	±	NUM
dti-1313	67	45	9.3	9.3	NUM
dti-1313	67	46	%	%	NOUN
dti-1313	67	47	(	(	PUNCT
dti-1313	67	48	n	n	NOUN
dti-1313	67	49	=	=	SYM
dti-1313	67	50	5	5	NUM
dti-1313	67	51	,	,	PUNCT
dti-1313	67	52	p	p	X
dti-1313	67	53	<	<	X
dti-1313	67	54	0.001	0.001	NUM
dti-1313	67	55	)	)	PUNCT
dti-1313	67	56	.	.	PUNCT
dti-1313	68	1	thus	thus	ADV
dti-1313	68	2	,	,	PUNCT
dti-1313	68	3	both	both	DET
dti-1313	68	4	l	l	NOUN
dti-1313	68	5	-	-	NOUN
dti-1313	68	6	nmma	nmma	PROPN
dti-1313	68	7	and	and	CCONJ
dti-1313	68	8	indomethacin	indomethacin	PROPN
dti-1313	68	9	affected	affect	VERB
dti-1313	68	10	the	the	DET
dti-1313	68	11	sinomenine	sinomenine	NOUN
dti-1313	68	12	-	-	PUNCT
dti-1313	68	13	induced	induce	VERB
dti-1313	68	14	relaxation	relaxation	NOUN
dti-1313	68	15	significantly	significantly	ADV
dti-1313	68	16	.	.	PUNCT
dti-1313	69	1	therefore	therefore	ADV
dti-1313	69	2	,	,	PUNCT
dti-1313	69	3	sinomenine	sinomenine	NOUN
dti-1313	69	4	possesses	possess	VERB
dti-1313	69	5	the	the	DET
dti-1313	69	6	pharmacological	pharmacological	ADJ
dti-1313	69	7	characteristics	characteristic	NOUN
dti-1313	69	8	for	for	ADP
dti-1313	69	9	modulation	modulation	NOUN
dti-1313	69	10	of	of	ADP
dti-1313	69	11	no	no	DET
dti-1313	69	12	synthesis	synthesis	NOUN
dti-1313	69	13	and	and	CCONJ
dti-1313	69	14	pg	pg	NOUN
dti-1313	69	15	production	production	NOUN
dti-1313	69	16	,	,	PUNCT
dti-1313	69	17	as	as	ADV
dti-1313	69	18	well	well	ADV
dti-1313	69	19	as	as	ADP
dti-1313	69	20	the	the	DET
dti-1313	69	21	inhibitions	inhibition	NOUN
dti-1313	69	22	of	of	ADP
dti-1313	69	23	ca2	ca2	PROPN
dti-1313	69	24	+	+	PROPN
dti-1313	69	25	channel	channel	NOUN
dti-1313	69	26	and	and	CCONJ
dti-1313	69	27	pk	pk	NOUN
dti-1313	69	28	-	-	NOUN
dti-1313	69	29	c	c	NOUN
dti-1313	69	30	and	and	CCONJ
dti-1313	69	31	the	the	DET
dti-1313	69	32	stimulation	stimulation	NOUN
dti-1313	69	33	of	of	ADP
dti-1313	69	34	β	β	NOUN
dti-1313	69	35	-	-	NOUN
dti-1313	69	36	adrenoceptor	adrenoceptor	NOUN
dti-1313	69	37	.	.	PUNCT
dti-1313	70	1	the	the	DET
dti-1313	70	2	possible	possible	ADJ
dti-1313	70	3	mechanisms	mechanism	NOUN
dti-1313	70	4	for	for	ADP
dti-1313	70	5	the	the	DET
dti-1313	70	6	vasodilating	vasodilate	VERB
dti-1313	70	7	actions	action	NOUN
dti-1313	70	8	of	of	ADP
dti-1313	70	9	sinomenine	sinomenine	NOUN
dti-1313	70	10	are	be	AUX
dti-1313	70	11	summarized	summarize	VERB
dti-1313	70	12	in	in	ADP
dti-1313	70	13	fig	fig	NOUN
dti-1313	70	14	.	.	PUNCT
dti-1313	71	1	3	3	X
dti-1313	71	2	.	.	X
dti-1313	71	3	cardiac	cardiac	ADJ
dti-1313	71	4	electropharmacology	electropharmacology	NOUN
dti-1313	71	5	cardiac	cardiac	ADJ
dti-1313	71	6	cells	cell	NOUN
dti-1313	71	7	were	be	AUX
dti-1313	71	8	taken	take	VERB
dti-1313	71	9	from	from	ADP
dti-1313	71	10	the	the	DET
dti-1313	71	11	ventricle	ventricle	NOUN
dti-1313	71	12	muscles	muscle	NOUN
dti-1313	71	13	of	of	ADP
dti-1313	71	14	guinea	guinea	NOUN
dti-1313	71	15	pig	pig	NOUN
dti-1313	71	16	hearts	heart	NOUN
dti-1313	71	17	,	,	PUNCT
dti-1313	71	18	using	use	VERB
dti-1313	71	19	methods	method	NOUN
dti-1313	71	20	similar	similar	ADJ
dti-1313	71	21	to	to	ADP
dti-1313	71	22	those	those	PRON
dti-1313	71	23	described	describe	VERB
dti-1313	71	24	previously	previously	ADV
dti-1313	71	25	(	(	PUNCT
dti-1313	71	26	satoh	satoh	NOUN
dti-1313	71	27	,	,	PUNCT
dti-1313	71	28	2003	2003	NUM
dti-1313	71	29	,	,	PUNCT
dti-1313	71	30	2005	2005	NUM
dti-1313	71	31	)	)	PUNCT
dti-1313	71	32	.	.	PUNCT
dti-1313	72	1	currentclamp	currentclamp	PROPN
dti-1313	72	2	and	and	CCONJ
dti-1313	72	3	whole	whole	ADJ
dti-1313	72	4	-	-	PUNCT
dti-1313	72	5	cell	cell	NOUN
dti-1313	72	6	voltage	voltage	NOUN
dti-1313	72	7	-	-	PUNCT
dti-1313	72	8	clamp	clamp	NOUN
dti-1313	72	9	were	be	AUX
dti-1313	72	10	performed	perform	VERB
dti-1313	72	11	using	use	VERB
dti-1313	72	12	an	an	DET
dti-1313	72	13	axopatch	axopatch	ADJ
dti-1313	72	14	patch	patch	ADJ
dti-1313	72	15	-	-	PUNCT
dti-1313	72	16	clamp	clamp	NOUN
dti-1313	72	17	amplifi	amplifi	NOUN
dti-1313	72	18	er	er	INTJ
dti-1313	72	19	(	(	PUNCT
dti-1313	72	20	axon	axon	NOUN
dti-1313	72	21	instruments	instrument	NOUN
dti-1313	72	22	,	,	PUNCT
dti-1313	72	23	burlingame	burlingame	PROPN
dti-1313	72	24	,	,	PUNCT
dti-1313	72	25	c.a	c.a	PROPN
dti-1313	72	26	,	,	PUNCT
dti-1313	72	27	u.s.a	u.s.a	NOUN
dti-1313	72	28	.	.	PUNCT
dti-1313	72	29	)	)	PUNCT
dti-1313	72	30	and	and	CCONJ
dti-1313	72	31	standard	standard	ADJ
dti-1313	72	32	techniques	technique	NOUN
dti-1313	72	33	.	.	PUNCT
dti-1313	73	1	current	current	ADJ
dti-1313	73	2	-	-	PUNCT
dti-1313	73	3	clamp	clamp	NOUN
dti-1313	73	4	experiments	experiment	NOUN
dti-1313	73	5	were	be	AUX
dti-1313	73	6	carried	carry	VERB
dti-1313	73	7	out	out	ADP
dti-1313	73	8	to	to	PART
dti-1313	73	9	examine	examine	VERB
dti-1313	73	10	the	the	DET
dti-1313	73	11	modulation	modulation	NOUN
dti-1313	73	12	of	of	ADP
dti-1313	73	13	the	the	DET
dti-1313	73	14	action	action	NOUN
dti-1313	73	15	potential	potential	ADJ
dti-1313	73	16	confi	confi	ADJ
dti-1313	73	17	guration	guration	NOUN
dti-1313	73	18	in	in	ADP
dti-1313	73	19	guinea	guinea	NOUN
dti-1313	73	20	pig	pig	NOUN
dti-1313	73	21	ventricular	ventricular	ADJ
dti-1313	73	22	muscles	muscle	NOUN
dti-1313	73	23	(	(	PUNCT
dti-1313	73	24	fig	fig	NOUN
dti-1313	73	25	.	.	PUNCT
dti-1313	74	1	4a	4a	NOUN
dti-1313	74	2	)	)	PUNCT
dti-1313	74	3	(	(	PUNCT
dti-1313	74	4	satoh	satoh	NOUN
dti-1313	74	5	,	,	PUNCT
dti-1313	74	6	2005	2005	NUM
dti-1313	74	7	)	)	PUNCT
dti-1313	74	8	.	.	PUNCT
dti-1313	75	1	sinomenine	sinomenine	NOUN
dti-1313	75	2	at	at	ADP
dti-1313	75	3	300	300	NUM
dti-1313	75	4	µm	µm	ADP
dti-1313	75	5	and	and	CCONJ
dti-1313	75	6	1	1	NUM
dti-1313	75	7	mm	mm	NOUN
dti-1313	75	8	increased	increase	VERB
dti-1313	75	9	the	the	DET
dti-1313	75	10	75	75	NUM
dti-1313	75	11	%	%	NOUN
dti-1313	75	12	repolarization	repolarization	NOUN
dti-1313	75	13	of	of	ADP
dti-1313	75	14	action	action	NOUN
dti-1313	75	15	potential	potential	ADJ
dti-1313	75	16	duration	duration	NOUN
dti-1313	75	17	(	(	PUNCT
dti-1313	75	18	apd75	apd75	PROPN
dti-1313	75	19	)	)	PUNCT
dti-1313	75	20	by	by	ADP
dti-1313	75	21	24.9	24.9	NUM
dti-1313	75	22	±	±	NUM
dti-1313	75	23	3.5	3.5	NUM
dti-1313	75	24	%	%	NOUN
dti-1313	75	25	(	(	PUNCT
dti-1313	75	26	n	n	NOUN
dti-1313	75	27	=	=	SYM
dti-1313	75	28	6	6	NUM
dti-1313	75	29	,	,	PUNCT
dti-1313	75	30	p	p	X
dti-1313	75	31	<	<	X
dti-1313	75	32	0.05	0.05	NUM
dti-1313	75	33	)	)	PUNCT
dti-1313	75	34	and	and	CCONJ
dti-1313	75	35	by	by	ADP
dti-1313	75	36	43.7	43.7	NUM
dti-1313	75	37	±	±	NUM
dti-1313	75	38	3.3	3.3	NUM
dti-1313	75	39	%	%	NOUN
dti-1313	75	40	(	(	PUNCT
dti-1313	75	41	n	n	NOUN
dti-1313	75	42	=	=	SYM
dti-1313	75	43	6	6	NUM
dti-1313	75	44	,	,	PUNCT
dti-1313	75	45	p	p	X
dti-1313	75	46	<	<	X
dti-1313	75	47	0.001	0.001	NUM
dti-1313	75	48	)	)	PUNCT
dti-1313	75	49	,	,	PUNCT
dti-1313	75	50	respectively	respectively	ADV
dti-1313	75	51	.	.	PUNCT
dti-1313	76	1	sinomenine	sinomenine	NOUN
dti-1313	76	2	at	at	ADP
dti-1313	76	3	1	1	NUM
dti-1313	76	4	mm	mm	NOUN
dti-1313	76	5	decreased	decrease	VERB
dti-1313	76	6	the	the	DET
dti-1313	76	7	amplitude	amplitude	NOUN
dti-1313	76	8	(	(	PUNCT
dti-1313	76	9	apa	apa	PROPN
dti-1313	76	10	)	)	PUNCT
dti-1313	76	11	,	,	PUNCT
dti-1313	76	12	but	but	CCONJ
dti-1313	76	13	not	not	PART
dti-1313	76	14	signifi	signifi	NOUN
dti-1313	76	15	cantly	cantly	ADV
dti-1313	76	16	(	(	PUNCT
dti-1313	76	17	0.9	0.9	NUM
dti-1313	76	18	±	±	NUM
dti-1313	76	19	2.1	2.1	NUM
dti-1313	76	20	%	%	NOUN
dti-1313	76	21	,	,	PUNCT
dti-1313	76	22	n	n	NOUN
dti-1313	76	23	=	=	SYM
dti-1313	76	24	5	5	NUM
dti-1313	76	25	)	)	PUNCT
dti-1313	76	26	.	.	PUNCT
dti-1313	77	1	the	the	DET
dti-1313	77	2	resting	rest	VERB
dti-1313	77	3	potential	potential	NOUN
dti-1313	77	4	was	be	AUX
dti-1313	77	5	not	not	PART
dti-1313	77	6	affected	affect	VERB
dti-1313	77	7	.	.	PUNCT
dti-1313	78	1	the	the	DET
dti-1313	78	2	modulation	modulation	NOUN
dti-1313	78	3	of	of	ADP
dti-1313	78	4	l	l	NOUN
dti-1313	78	5	-	-	PUNCT
dti-1313	78	6	type	type	NOUN
dti-1313	78	7	ca2	ca2	PROPN
dti-1313	78	8	+	+	PROPN
dti-1313	78	9	current	current	ADJ
dti-1313	78	10	(	(	PUNCT
dti-1313	78	11	ica	ica	PROPN
dti-1313	78	12	)	)	PUNCT
dti-1313	78	13	was	be	AUX
dti-1313	78	14	investigated	investigate	VERB
dti-1313	78	15	.	.	PUNCT
dti-1313	79	1	test	test	NOUN
dti-1313	79	2	pulses	pulse	NOUN
dti-1313	79	3	were	be	AUX
dti-1313	79	4	applied	apply	VERB
dti-1313	79	5	to	to	ADP
dti-1313	79	6	0	0	NUM
dti-1313	79	7	mv	mv	PROPN
dti-1313	79	8	from	from	ADP
dti-1313	79	9	a	a	DET
dti-1313	79	10	holding	hold	VERB
dti-1313	79	11	potential	potential	NOUN
dti-1313	79	12	of	of	ADP
dti-1313	79	13	–	–	PUNCT
dti-1313	79	14	30	30	NUM
dti-1313	79	15	mv	mv	NOUN
dti-1313	79	16	.	.	PUNCT
dti-1313	80	1	the	the	DET
dti-1313	80	2	average	average	ADJ
dti-1313	80	3	capacitance	capacitance	NOUN
dti-1313	80	4	was	be	AUX
dti-1313	80	5	84.1	84.1	NUM
dti-1313	80	6	±	±	NUM
dti-1313	80	7	2.4	2.4	NUM
dti-1313	80	8	pf	pf	NOUN
dti-1313	80	9	(	(	PUNCT
dti-1313	80	10	n	n	NOUN
dti-1313	80	11	=	=	NUM
dti-1313	80	12	23	23	NUM
dti-1313	80	13	)	)	PUNCT
dti-1313	80	14	.	.	PUNCT
dti-1313	81	1	at	at	ADP
dti-1313	81	2	1	1	NUM
dti-1313	81	3	mm	mm	NOUN
dti-1313	81	4	sinomenine	sinomenine	NOUN
dti-1313	81	5	inhibited	inhibit	VERB
dti-1313	81	6	the	the	DET
dti-1313	81	7	ica	ica	PROPN
dti-1313	81	8	at	at	ADP
dti-1313	81	9	0	0	NUM
dti-1313	81	10	mv	mv	X
dti-1313	81	11	by	by	ADP
dti-1313	81	12	18.2	18.2	NUM
dti-1313	81	13	±	±	NUM
dti-1313	81	14	2.1	2.1	NUM
dti-1313	81	15	%	%	NOUN
dti-1313	81	16	(	(	PUNCT
dti-1313	81	17	n	n	NOUN
dti-1313	81	18	=	=	SYM
dti-1313	81	19	6	6	NUM
dti-1313	81	20	,	,	PUNCT
dti-1313	81	21	p	p	X
dti-1313	81	22	<	<	X
dti-1313	81	23	0.05	0.05	NUM
dti-1313	81	24	)	)	PUNCT
dti-1313	81	25	.	.	PUNCT
dti-1313	82	1	at	at	ADP
dti-1313	82	2	1	1	NUM
dti-1313	82	3	mm	mm	NOUN
dti-1313	82	4	,	,	PUNCT
dti-1313	82	5	the	the	DET
dti-1313	82	6	delayed	delay	VERB
dti-1313	82	7	rectifi	rectifi	NOUN
dti-1313	82	8	er	er	INTJ
dti-1313	82	9	k+	k+	NOUN
dti-1313	82	10	currents	current	NOUN
dti-1313	82	11	(	(	PUNCT
dti-1313	82	12	ik	ik	PROPN
dti-1313	82	13	)	)	PUNCT
dti-1313	82	14	at	at	ADP
dti-1313	82	15	60	60	NUM
dti-1313	82	16	mv	mv	PROPN
dti-1313	82	17	was	be	AUX
dti-1313	82	18	inhibited	inhibit	VERB
dti-1313	82	19	by	by	ADP
dti-1313	82	20	16.2	16.2	NUM
dti-1313	82	21	±	±	NUM
dti-1313	82	22	2.6	2.6	NUM
dti-1313	82	23	%	%	NOUN
dti-1313	82	24	(	(	PUNCT
dti-1313	82	25	n	n	NOUN
dti-1313	82	26	=	=	SYM
dti-1313	82	27	6	6	NUM
dti-1313	82	28	,	,	PUNCT
dti-1313	82	29	p	p	X
dti-1313	82	30	<	<	X
dti-1313	82	31	0.05	0.05	NUM
dti-1313	82	32	)	)	PUNCT
dti-1313	82	33	(	(	PUNCT
dti-1313	82	34	fig	fig	NOUN
dti-1313	82	35	.	.	PUNCT
dti-1313	83	1	4b	4b	PROPN
dti-1313	83	2	)	)	PUNCT
dti-1313	83	3	,	,	PUNCT
dti-1313	83	4	and	and	CCONJ
dti-1313	83	5	the	the	DET
dti-1313	83	6	inwardly	inwardly	ADV
dti-1313	83	7	rectifying	rectify	VERB
dti-1313	83	8	k+	k+	NOUN
dti-1313	83	9	current	current	ADJ
dti-1313	83	10	(	(	PUNCT
dti-1313	83	11	ik1	ik1	ADV
dti-1313	83	12	)	)	PUNCT
dti-1313	83	13	at	at	ADP
dti-1313	83	14	-120	-120	PROPN
dti-1313	83	15	mv	mv	X
dti-1313	83	16	by	by	ADP
dti-1313	83	17	47.2	47.2	NUM
dti-1313	83	18	±	±	NUM
dti-1313	83	19	3.8	3.8	NUM
dti-1313	83	20	%	%	NOUN
dti-1313	83	21	(	(	PUNCT
dti-1313	83	22	n	n	NOUN
dti-1313	83	23	=	=	SYM
dti-1313	83	24	6	6	NUM
dti-1313	83	25	,	,	PUNCT
dti-1313	83	26	p	p	X
dti-1313	83	27	<	<	X
dti-1313	83	28	0.01	0.01	NUM
dti-1313	83	29	)	)	PUNCT
dti-1313	83	30	.	.	PUNCT
dti-1313	84	1	s	s	PART
dti-1313	84	2	inomenine	inomenine	NOUN
dti-1313	84	3	0	0	NUM
dti-1313	84	4	10	10	NUM
dti-1313	84	5	20	20	NUM
dti-1313	84	6	30	30	NUM
dti-1313	84	7	40	40	NUM
dti-1313	84	8	50	50	NUM
dti-1313	84	9	60	60	NUM
dti-1313	84	10	70	70	NUM
dti-1313	84	11	80	80	NUM
dti-1313	84	12	90	90	NUM
dti-1313	84	13	100	100	NUM
dti-1313	84	14	0.1	0.1	NUM
dti-1313	84	15	0.3	0.3	NUM
dti-1313	84	16	1	1	NUM
dti-1313	84	17	3	3	NUM
dti-1313	84	18	10	10	NUM
dti-1313	84	19	30	30	NUM
dti-1313	84	20	100	100	NUM
dti-1313	84	21	r	r	NOUN
dti-1313	84	22	el	el	NOUN
dti-1313	84	23	ax	ax	NOUN
dti-1313	84	24	at	at	ADP
dti-1313	84	25	io	io	PROPN
dti-1313	84	26	nn	nn	PROPN
dti-1313	84	27	(	(	PUNCT
dti-1313	84	28	%	%	NOUN
dti-1313	84	29	)	)	PUNCT
dti-1313	84	30	ne	ne	PROPN
dti-1313	85	1	p	p	NOUN
dti-1313	85	2	db	db	PROPN
dti-1313	85	3	kc	kc	NOUN
dti-1313	85	4	μm	μm	NUM
dti-1313	85	5	figure	figure	NOUN
dti-1313	85	6	1	1	NUM
dti-1313	85	7	.	.	PUNCT
dti-1313	85	8	concentration	concentration	NOUN
dti-1313	85	9	-	-	PUNCT
dti-1313	85	10	dependent	dependent	ADJ
dti-1313	85	11	relaxation	relaxation	NOUN
dti-1313	85	12	of	of	ADP
dti-1313	85	13	sinomenine	sinomenine	NOUN
dti-1313	85	14	on	on	ADP
dti-1313	85	15	ne-	ne-	PROPN
dti-1313	85	16	,	,	PUNCT
dti-1313	85	17	pdband	pdband	PROPN
dti-1313	85	18	kcl	kcl	NOUN
dti-1313	85	19	-	-	PUNCT
dti-1313	85	20	induced	induce	VERB
dti-1313	85	21	vasorelaxations	vasorelaxation	NOUN
dti-1313	85	22	.	.	PUNCT
dti-1313	86	1	symbols	symbol	NOUN
dti-1313	86	2	used	use	VERB
dti-1313	86	3	are	be	AUX
dti-1313	86	4	sinomenine	sinomenine	NOUN
dti-1313	86	5	in	in	ADP
dti-1313	86	6	pretreatments	pretreatment	NOUN
dti-1313	86	7	with	with	ADP
dti-1313	86	8	ne	ne	PROPN
dti-1313	86	9	(	(	PUNCT
dti-1313	86	10	open	open	ADJ
dti-1313	86	11	circles	circle	NOUN
dti-1313	86	12	,	,	PUNCT
dti-1313	86	13	n	n	NOUN
dti-1313	86	14	=	=	SYM
dti-1313	86	15	6	6	NUM
dti-1313	86	16	)	)	PUNCT
dti-1313	86	17	,	,	PUNCT
dti-1313	86	18	pdb	pdb	PROPN
dti-1313	86	19	(	(	PUNCT
dti-1313	86	20	triangles	triangle	NOUN
dti-1313	86	21	,	,	PUNCT
dti-1313	86	22	n	n	NOUN
dti-1313	86	23	=	=	SYM
dti-1313	86	24	6	6	NUM
dti-1313	86	25	)	)	PUNCT
dti-1313	86	26	and	and	CCONJ
dti-1313	86	27	kcl	kcl	PROPN
dti-1313	86	28	(	(	PUNCT
dti-1313	86	29	squares	square	NOUN
dti-1313	86	30	,	,	PUNCT
dti-1313	86	31	n	n	NOUN
dti-1313	86	32	=	=	PROPN
dti-1313	86	33	6	6	NUM
dti-1313	86	34	)	)	PUNCT
dti-1313	86	35	.	.	PUNCT
dti-1313	87	1	values	value	NOUN
dti-1313	87	2	(	(	PUNCT
dti-1313	87	3	%	%	INTJ
dti-1313	87	4	)	)	PUNCT
dti-1313	87	5	represent	represent	VERB
dti-1313	87	6	mean	mean	PROPN
dti-1313	87	7	±	±	NUM
dti-1313	87	8	s.e.m	s.e.m	NOUN
dti-1313	87	9	.	.	PUNCT
dti-1313	88	1	*	*	PUNCT
dti-1313	88	2	:	:	PUNCT
dti-1313	88	3	p	p	X
dti-1313	88	4	<	<	X
dti-1313	88	5	0.05	0.05	NUM
dti-1313	88	6	,	,	PUNCT
dti-1313	88	7	*	*	PUNCT
dti-1313	88	8	*	*	PUNCT
dti-1313	88	9	:	:	PUNCT
dti-1313	88	10	p	p	X
dti-1313	88	11	<	<	X
dti-1313	88	12	0.01	0.01	NUM
dti-1313	88	13	,	,	PUNCT
dti-1313	88	14	*	*	PUNCT
dti-1313	88	15	*	*	PUNCT
dti-1313	88	16	*	*	PUNCT
dti-1313	88	17	:	:	PUNCT
dti-1313	88	18	p	p	X
dti-1313	88	19	<	<	X
dti-1313	88	20	0.001	0.001	NUM
dti-1313	88	21	,	,	PUNCT
dti-1313	88	22	with	with	ADP
dti-1313	88	23	respect	respect	NOUN
dti-1313	88	24	to	to	ADP
dti-1313	88	25	control	control	NOUN
dti-1313	88	26	value	value	NOUN
dti-1313	88	27	.	.	PUNCT
dti-1313	89	1	satoh	satoh	NOUN
dti-1313	89	2	et	et	NOUN
dti-1313	89	3	al.indd	al.indd	X
dti-1313	89	4	3	3	NUM
dti-1313	89	5	5/14/2007	5/14/2007	NUM
dti-1313	89	6	8:59:10	8:59:10	PROPN
dti-1313	89	7	pm	pm	NOUN
dti-1313	89	8	99	99	NUM
dti-1313	89	9	nishida	nishida	ADJ
dti-1313	89	10	and	and	CCONJ
dti-1313	89	11	satoh	satoh	NOUN
dti-1313	89	12	drug	drug	NOUN
dti-1313	89	13	target	target	NOUN
dti-1313	89	14	insights	insight	NOUN
dti-1313	89	15	2007	2007	NUM
dti-1313	89	16	:	:	SYM
dti-1313	89	17	2	2	NUM
dti-1313	89	18	in	in	ADP
dti-1313	89	19	multicellular	multicellular	ADJ
dti-1313	89	20	preparations	preparation	NOUN
dti-1313	90	1	,	,	PUNCT
dti-1313	90	2	the	the	DET
dti-1313	90	3	modulation	modulation	NOUN
dti-1313	90	4	of	of	ADP
dti-1313	90	5	action	action	NOUN
dti-1313	90	6	potential	potential	ADJ
dti-1313	90	7	confi	confi	NOUN
dti-1313	90	8	guration	guration	NOUN
dti-1313	90	9	by	by	ADP
dti-1313	90	10	sinomenine	sinomenine	NOUN
dti-1313	90	11	was	be	AUX
dti-1313	90	12	also	also	ADV
dti-1313	90	13	examined	examine	VERB
dti-1313	90	14	(	(	PUNCT
dti-1313	90	15	satoh	satoh	NOUN
dti-1313	90	16	,	,	PUNCT
dti-1313	90	17	2005	2005	NUM
dti-1313	90	18	)	)	PUNCT
dti-1313	90	19	.	.	PUNCT
dti-1313	91	1	the	the	DET
dti-1313	91	2	preparations	preparation	NOUN
dti-1313	91	3	were	be	AUX
dti-1313	91	4	stimulated	stimulate	VERB
dti-1313	91	5	at	at	ADP
dti-1313	91	6	1	1	NUM
dti-1313	91	7	hz	hz	NOUN
dti-1313	91	8	.	.	PROPN
dti-1313	91	9	sinomenine	sinomenine	NOUN
dti-1313	91	10	(	(	PUNCT
dti-1313	91	11	100	100	NUM
dti-1313	91	12	µm	µm	NOUN
dti-1313	91	13	to	to	ADP
dti-1313	91	14	1	1	NUM
dti-1313	91	15	mm	mm	NOUN
dti-1313	91	16	)	)	PUNCT
dti-1313	91	17	had	have	VERB
dti-1313	91	18	inhibitory	inhibitory	ADJ
dti-1313	91	19	effects	effect	NOUN
dti-1313	91	20	on	on	ADP
dti-1313	91	21	the	the	DET
dti-1313	91	22	action	action	NOUN
dti-1313	91	23	potentials	potential	VERB
dti-1313	91	24	,	,	PUNCT
dti-1313	91	25	and	and	CCONJ
dti-1313	91	26	tended	tend	VERB
dti-1313	91	27	to	to	PART
dti-1313	91	28	increase	increase	VERB
dti-1313	91	29	the	the	DET
dti-1313	91	30	action	action	NOUN
dti-1313	91	31	potential	potential	ADJ
dti-1313	91	32	durations	duration	NOUN
dti-1313	91	33	(	(	PUNCT
dti-1313	91	34	apd	apd	PROPN
dti-1313	91	35	)	)	PUNCT
dti-1313	91	36	;	;	PUNCT
dti-1313	91	37	at	at	ADP
dti-1313	91	38	1	1	NUM
dti-1313	91	39	mm	mm	NOUN
dti-1313	91	40	,	,	PUNCT
dti-1313	91	41	by	by	ADP
dti-1313	91	42	4.1±	4.1±	NUM
dti-1313	91	43	1.6	1.6	NUM
dti-1313	91	44	%	%	NOUN
dti-1313	91	45	(	(	PUNCT
dti-1313	91	46	n	n	NOUN
dti-1313	91	47	=	=	SYM
dti-1313	91	48	6	6	NUM
dti-1313	91	49	)	)	PUNCT
dti-1313	91	50	in	in	ADP
dti-1313	91	51	apd50	apd50	ADJ
dti-1313	91	52	and	and	CCONJ
dti-1313	91	53	by	by	ADP
dti-1313	91	54	4.5	4.5	NUM
dti-1313	91	55	±	±	NUM
dti-1313	91	56	1.4	1.4	NUM
dti-1313	91	57	%	%	NOUN
dti-1313	91	58	(	(	PUNCT
dti-1313	91	59	n	n	NOUN
dti-1313	91	60	=	=	SYM
dti-1313	91	61	6	6	NUM
dti-1313	91	62	)	)	PUNCT
dti-1313	91	63	in	in	ADP
dti-1313	91	64	apd90	apd90	PROPN
dti-1313	91	65	(	(	PUNCT
dti-1313	91	66	but	but	CCONJ
dti-1313	91	67	not	not	PART
dti-1313	91	68	signifi	signifi	VERB
dti-1313	91	69	cantly	cantly	ADV
dti-1313	91	70	)	)	PUNCT
dti-1313	91	71	.	.	PUNCT
dti-1313	92	1	the	the	DET
dti-1313	92	2	maximum	maximum	ADJ
dti-1313	92	3	rate	rate	NOUN
dti-1313	92	4	of	of	ADP
dti-1313	92	5	depolarization	depolarization	NOUN
dti-1313	92	6	(	(	PUNCT
dti-1313	92	7	vmax	vmax	PROPN
dti-1313	92	8	)	)	PUNCT
dti-1313	92	9	was	be	AUX
dti-1313	92	10	also	also	ADV
dti-1313	92	11	inhibited	inhibit	VERB
dti-1313	92	12	by	by	ADP
dti-1313	92	13	20.0	20.0	NUM
dti-1313	92	14	±	±	NUM
dti-1313	92	15	2.4	2.4	NUM
dti-1313	92	16	%	%	NOUN
dti-1313	92	17	(	(	PUNCT
dti-1313	92	18	n	n	NOUN
dti-1313	92	19	=	=	SYM
dti-1313	92	20	6	6	NUM
dti-1313	92	21	,	,	PUNCT
dti-1313	92	22	p	p	X
dti-1313	92	23	<	<	X
dti-1313	92	24	0.05	0.05	NUM
dti-1313	92	25	)	)	PUNCT
dti-1313	92	26	at	at	ADP
dti-1313	92	27	300	300	NUM
dti-1313	92	28	µm	µm	NOUN
dti-1313	92	29	and	and	CCONJ
dti-1313	92	30	by	by	ADP
dti-1313	92	31	32.1	32.1	NUM
dti-1313	92	32	±	±	NUM
dti-1313	92	33	3.3	3.3	NUM
dti-1313	92	34	%	%	NOUN
dti-1313	92	35	(	(	PUNCT
dti-1313	92	36	n	n	NOUN
dti-1313	92	37	=	=	SYM
dti-1313	92	38	6	6	NUM
dti-1313	92	39	,	,	PUNCT
dti-1313	92	40	p	p	X
dti-1313	92	41	<	<	X
dti-1313	92	42	0.05	0.05	NUM
dti-1313	92	43	)	)	PUNCT
dti-1313	92	44	at	at	ADP
dti-1313	92	45	1	1	NUM
dti-1313	92	46	mm	mm	NOUN
dti-1313	92	47	of	of	ADP
dti-1313	92	48	sinomenine	sinomenine	NOUN
dti-1313	92	49	.	.	PUNCT
dti-1313	93	1	in	in	ADP
dti-1313	93	2	high	high	ADJ
dti-1313	93	3	extracellular	extracellular	ADJ
dti-1313	93	4	ca2	ca2	PROPN
dti-1313	93	5	+	+	X
dti-1313	93	6	(	(	PUNCT
dti-1313	93	7	[	[	X
dti-1313	93	8	ca2+]o	ca2+]o	NOUN
dti-1313	93	9	)	)	PUNCT
dti-1313	93	10	solution	solution	NOUN
dti-1313	93	11	(	(	PUNCT
dti-1313	93	12	5.4	5.4	NUM
dti-1313	93	13	mm	mm	NOUN
dti-1313	93	14	)	)	PUNCT
dti-1313	93	15	to	to	PART
dti-1313	93	16	cause	cause	VERB
dti-1313	93	17	cellular	cellular	ADJ
dti-1313	93	18	ca2	ca2	PROPN
dti-1313	93	19	+	+	PROPN
dti-1313	93	20	overload	overload	NOUN
dti-1313	93	21	,	,	PUNCT
dti-1313	93	22	abnormal	abnormal	ADJ
dti-1313	93	23	action	action	NOUN
dti-1313	93	24	potentials	potential	NOUN
dti-1313	93	25	occurred	occur	VERB
dti-1313	93	26	irregularly	irregularly	ADV
dti-1313	93	27	,	,	PUNCT
dti-1313	93	28	in	in	ADP
dti-1313	93	29	spite	spite	NOUN
dti-1313	93	30	of	of	ADP
dti-1313	93	31	constant	constant	ADJ
dti-1313	93	32	stimulation	stimulation	NOUN
dti-1313	93	33	(	(	PUNCT
dti-1313	93	34	1	1	NUM
dti-1313	93	35	hz	hz	NOUN
dti-1313	93	36	)	)	PUNCT
dti-1313	93	37	(	(	PUNCT
dti-1313	93	38	satoh	satoh	NOUN
dti-1313	93	39	,	,	PUNCT
dti-1313	93	40	2005	2005	NUM
dti-1313	93	41	)	)	PUNCT
dti-1313	93	42	.	.	PUNCT
dti-1313	94	1	application	application	NOUN
dti-1313	94	2	of	of	ADP
dti-1313	94	3	300	300	NUM
dti-1313	94	4	µm	µm	NOUN
dti-1313	94	5	sinomenine	sinomenine	NOUN
dti-1313	94	6	suppressed	suppress	VERB
dti-1313	94	7	and	and	CCONJ
dti-1313	94	8	abolished	abolish	VERB
dti-1313	94	9	the	the	DET
dti-1313	94	10	abnormal	abnormal	ADJ
dti-1313	94	11	action	action	NOUN
dti-1313	94	12	potentials	potential	VERB
dti-1313	94	13	(	(	PUNCT
dti-1313	94	14	dysrhythmias	dysrhythmias	PROPN
dti-1313	94	15	)	)	PUNCT
dti-1313	94	16	(	(	PUNCT
dti-1313	94	17	fig	fig	NOUN
dti-1313	94	18	.	.	PUNCT
dti-1313	94	19	5	5	NUM
dti-1313	94	20	)	)	PUNCT
dti-1313	94	21	.	.	PUNCT
dti-1313	95	1	the	the	DET
dti-1313	95	2	changes	change	NOUN
dti-1313	95	3	in	in	ADP
dti-1313	95	4	the	the	DET
dti-1313	95	5	action	action	NOUN
dti-1313	95	6	potential	potential	ADJ
dti-1313	95	7	confi	confi	NOUN
dti-1313	95	8	gurations	guration	NOUN
dti-1313	95	9	and	and	CCONJ
dti-1313	95	10	the	the	DET
dti-1313	95	11	modulation	modulation	NOUN
dti-1313	95	12	of	of	ADP
dti-1313	95	13	the	the	DET
dti-1313	95	14	ionic	ionic	ADJ
dti-1313	95	15	channel	channel	NOUN
dti-1313	95	16	currents	current	NOUN
dti-1313	95	17	on	on	ADP
dti-1313	95	18	the	the	DET
dti-1313	95	19	membrane	membrane	NOUN
dti-1313	95	20	of	of	ADP
dti-1313	95	21	cardiomyocyte	cardiomyocyte	NOUN
dti-1313	95	22	by	by	ADP
dti-1313	95	23	sinomenine	sinomenine	NOUN
dti-1313	95	24	are	be	AUX
dti-1313	95	25	summarized	summarize	VERB
dti-1313	95	26	in	in	ADP
dti-1313	95	27	fig	fig	NOUN
dti-1313	95	28	.	.	PUNCT
dti-1313	96	1	6	6	NUM
dti-1313	96	2	.	.	X
dti-1313	96	3	immunomodulative	immunomodulative	ADJ
dti-1313	96	4	action	action	NOUN
dti-1313	96	5	sinomenium	sinomenium	PROPN
dti-1313	96	6	acutum	acutum	PROPN
dti-1313	96	7	has	have	AUX
dti-1313	96	8	been	be	AUX
dti-1313	96	9	used	use	VERB
dti-1313	96	10	for	for	ADP
dti-1313	96	11	treatment	treatment	NOUN
dti-1313	96	12	for	for	ADP
dti-1313	96	13	various	various	ADJ
dti-1313	96	14	rheumatic	rheumatic	ADJ
dti-1313	96	15	diseases	disease	NOUN
dti-1313	96	16	as	as	ADP
dti-1313	96	17	a	a	DET
dti-1313	96	18	chinese	chinese	ADJ
dti-1313	96	19	traditional	traditional	ADJ
dti-1313	96	20	medicine	medicine	NOUN
dti-1313	96	21	(	(	PUNCT
dti-1313	96	22	yamasaki	yamasaki	NOUN
dti-1313	96	23	,	,	PUNCT
dti-1313	96	24	1976	1976	NUM
dti-1313	96	25	;	;	PUNCT
dti-1313	96	26	liu	liu	PROPN
dti-1313	96	27	et	et	PROPN
dti-1313	96	28	al	al	PROPN
dti-1313	96	29	.	.	PROPN
dti-1313	96	30	1996	1996	NUM
dti-1313	96	31	)	)	PUNCT
dti-1313	96	32	.	.	PUNCT
dti-1313	97	1	in	in	ADP
dti-1313	97	2	basic	basic	ADJ
dti-1313	97	3	pharmacological	pharmacological	ADJ
dti-1313	97	4	studies	study	NOUN
dti-1313	97	5	of	of	ADP
dti-1313	97	6	sinomenium	sinomenium	PROPN
dti-1313	97	7	acutum	acutum	PROPN
dti-1313	97	8	,	,	PUNCT
dti-1313	97	9	the	the	DET
dti-1313	97	10	inhibitory	inhibitory	ADJ
dti-1313	97	11	actions	action	NOUN
dti-1313	97	12	on	on	ADP
dti-1313	97	13	some	some	DET
dti-1313	97	14	enzymes	enzyme	NOUN
dti-1313	97	15	relating	relate	VERB
dti-1313	97	16	to	to	ADP
dti-1313	97	17	infl	infl	PROPN
dti-1313	97	18	ammation	ammation	NOUN
dti-1313	97	19	have	have	AUX
dti-1313	97	20	been	be	AUX
dti-1313	97	21	shown	show	VERB
dti-1313	97	22	(	(	PUNCT
dti-1313	97	23	li	li	PROPN
dti-1313	97	24	et	et	PROPN
dti-1313	97	25	al	al	PROPN
dti-1313	97	26	.	.	PROPN
dti-1313	97	27	2003	2003	NUM
dti-1313	97	28	)	)	PUNCT
dti-1313	97	29	.	.	PUNCT
dti-1313	98	1	one	one	NUM
dti-1313	98	2	of	of	ADP
dti-1313	98	3	most	most	ADV
dti-1313	98	4	famous	famous	ADJ
dti-1313	98	5	pharmacological	pharmacological	ADJ
dti-1313	98	6	actions	action	NOUN
dti-1313	98	7	of	of	ADP
dti-1313	98	8	sinomenine	sinomenine	NOUN
dti-1313	98	9	is	be	AUX
dti-1313	98	10	an	an	DET
dti-1313	98	11	immunomodulative	immunomodulative	ADJ
dti-1313	98	12	effect	effect	NOUN
dti-1313	98	13	.	.	PUNCT
dti-1313	99	1	sinomenine	sinomenine	NOUN
dti-1313	99	2	is	be	AUX
dti-1313	99	3	also	also	ADV
dti-1313	99	4	clinically	clinically	ADV
dti-1313	99	5	used	use	VERB
dti-1313	99	6	for	for	ADP
dti-1313	99	7	ra	ra	PROPN
dti-1313	99	8	treatment	treatment	NOUN
dti-1313	99	9	(	(	PUNCT
dti-1313	99	10	yamasaki	yamasaki	NOUN
dti-1313	99	11	,	,	PUNCT
dti-1313	99	12	1976	1976	NUM
dti-1313	99	13	;	;	PUNCT
dti-1313	99	14	liu	liu	PROPN
dti-1313	99	15	et	et	PROPN
dti-1313	99	16	al	al	PROPN
dti-1313	99	17	.	.	PROPN
dti-1313	99	18	1996	1996	NUM
dti-1313	99	19	)	)	PUNCT
dti-1313	99	20	.	.	PUNCT
dti-1313	100	1	a	a	DET
dti-1313	100	2	lot	lot	NOUN
dti-1313	100	3	of	of	ADP
dti-1313	100	4	reports	report	NOUN
dti-1313	100	5	concerning	concern	VERB
dti-1313	100	6	about	about	ADP
dti-1313	100	7	not	not	PART
dti-1313	100	8	only	only	ADV
dti-1313	100	9	an	an	DET
dti-1313	100	10	anti	anti	ADJ
dti-1313	100	11	-	-	ADJ
dti-1313	100	12	rheumatic	rheumatic	ADJ
dti-1313	100	13	effect	effect	NOUN
dti-1313	100	14	,	,	PUNCT
dti-1313	100	15	but	but	CCONJ
dti-1313	100	16	also	also	ADV
dti-1313	100	17	anti	anti	ADJ
dti-1313	100	18	-	-	ADJ
dti-1313	100	19	inflammatory	inflammatory	ADJ
dti-1313	100	20	and	and	CCONJ
dti-1313	100	21	immunomodulative	immunomodulative	ADJ
dti-1313	100	22	effects	effect	NOUN
dti-1313	100	23	have	have	AUX
dti-1313	100	24	already	already	ADV
dti-1313	100	25	been	be	AUX
dti-1313	100	26	shown	show	VERB
dti-1313	100	27	.	.	PUNCT
dti-1313	101	1	as	as	ADP
dti-1313	101	2	anti	anti	ADJ
dti-1313	101	3	-	-	ADJ
dti-1313	101	4	rheumatic	rheumatic	ADJ
dti-1313	101	5	direct	direct	ADJ
dti-1313	101	6	effects	effect	NOUN
dti-1313	101	7	,	,	PUNCT
dti-1313	101	8	it	it	PRON
dti-1313	101	9	has	have	AUX
dti-1313	101	10	been	be	AUX
dti-1313	101	11	reported	report	VERB
dti-1313	101	12	that	that	SCONJ
dti-1313	101	13	sinomenine	sinomenine	NOUN
dti-1313	101	14	reduces	reduce	VERB
dti-1313	101	15	infl	infl	PROPN
dti-1313	101	16	ammatory	ammatory	NOUN
dti-1313	101	17	parameters	parameter	NOUN
dti-1313	101	18	and	and	CCONJ
dti-1313	101	19	attenuates	attenuate	VERB
dti-1313	101	20	proliferation	proliferation	NOUN
dti-1313	101	21	of	of	ADP
dti-1313	101	22	figure	figure	NOUN
dti-1313	101	23	2	2	NUM
dti-1313	101	24	.	.	X
dti-1313	101	25	modulation	modulation	NOUN
dti-1313	101	26	by	by	ADP
dti-1313	101	27	several	several	ADJ
dti-1313	101	28	inhibitors	inhibitor	NOUN
dti-1313	101	29	of	of	ADP
dti-1313	101	30	the	the	DET
dti-1313	101	31	relaxation	relaxation	NOUN
dti-1313	101	32	induced	induce	VERB
dti-1313	101	33	by	by	ADP
dti-1313	101	34	sinomenine	sinomenine	NOUN
dti-1313	101	35	.	.	PUNCT
dti-1313	102	1	symbols	symbol	NOUN
dti-1313	102	2	used	use	VERB
dti-1313	102	3	are	be	AUX
dti-1313	102	4	in	in	ADP
dti-1313	102	5	the	the	DET
dti-1313	102	6	absence	absence	NOUN
dti-1313	102	7	(	(	PUNCT
dti-1313	102	8	open	open	ADJ
dti-1313	102	9	circles	circle	NOUN
dti-1313	102	10	,	,	PUNCT
dti-1313	102	11	n	n	NOUN
dti-1313	102	12	=	=	SYM
dti-1313	102	13	6	6	NUM
dti-1313	102	14	)	)	PUNCT
dti-1313	102	15	,	,	PUNCT
dti-1313	102	16	in	in	ADP
dti-1313	102	17	the	the	DET
dti-1313	102	18	presence	presence	NOUN
dti-1313	102	19	of	of	ADP
dti-1313	102	20	100	100	NUM
dti-1313	102	21	µm	µm	ADP
dti-1313	102	22	l	l	NOUN
dti-1313	102	23	-	-	PROPN
dti-1313	102	24	nmma	nmma	PROPN
dti-1313	102	25	(	(	PUNCT
dti-1313	102	26	open	open	ADJ
dti-1313	102	27	triangles	triangle	NOUN
dti-1313	102	28	,	,	PUNCT
dti-1313	102	29	n	n	NOUN
dti-1313	102	30	=	=	SYM
dti-1313	102	31	5	5	NUM
dti-1313	102	32	)	)	PUNCT
dti-1313	102	33	,	,	PUNCT
dti-1313	102	34	10	10	NUM
dti-1313	102	35	µm	µm	ADP
dti-1313	102	36	indomethacin	indomethacin	X
dti-1313	102	37	(	(	PUNCT
dti-1313	102	38	open	open	ADJ
dti-1313	102	39	squares	square	NOUN
dti-1313	102	40	,	,	PUNCT
dti-1313	102	41	n	n	NOUN
dti-1313	102	42	=	=	SYM
dti-1313	102	43	5	5	NUM
dti-1313	102	44	)	)	PUNCT
dti-1313	102	45	,	,	PUNCT
dti-1313	102	46	0.1	0.1	NUM
dti-1313	102	47	µm	µm	ADP
dti-1313	102	48	nicardipine	nicardipine	NOUN
dti-1313	102	49	(	(	PUNCT
dti-1313	102	50	closed	closed	ADJ
dti-1313	102	51	circles	circle	NOUN
dti-1313	102	52	,	,	PUNCT
dti-1313	102	53	n	n	NOUN
dti-1313	102	54	=	=	SYM
dti-1313	102	55	5	5	NUM
dti-1313	102	56	)	)	PUNCT
dti-1313	102	57	,	,	PUNCT
dti-1313	102	58	0.3	0.3	NUM
dti-1313	102	59	µm	µm	X
dti-1313	102	60	propranolol	propranolol	PROPN
dti-1313	102	61	(	(	PUNCT
dti-1313	102	62	closed	close	VERB
dti-1313	102	63	triangles	triangle	NOUN
dti-1313	102	64	,	,	PUNCT
dti-1313	102	65	n	n	NOUN
dti-1313	102	66	=	=	SYM
dti-1313	102	67	5	5	NUM
dti-1313	102	68	)	)	PUNCT
dti-1313	102	69	,	,	PUNCT
dti-1313	102	70	and	and	CCONJ
dti-1313	102	71	30	30	NUM
dti-1313	102	72	nm	nm	NOUN
dti-1313	102	73	staurosporine	staurosporine	NOUN
dti-1313	102	74	(	(	PUNCT
dti-1313	102	75	closed	closed	ADJ
dti-1313	102	76	squares	square	NOUN
dti-1313	102	77	,	,	PUNCT
dti-1313	102	78	n	n	NOUN
dti-1313	102	79	=	=	SYM
dti-1313	102	80	5	5	NUM
dti-1313	102	81	)	)	PUNCT
dti-1313	102	82	.	.	PUNCT
dti-1313	103	1	values	value	NOUN
dti-1313	103	2	(	(	PUNCT
dti-1313	103	3	%	%	INTJ
dti-1313	103	4	)	)	PUNCT
dti-1313	103	5	represent	represent	VERB
dti-1313	103	6	mean	mean	PROPN
dti-1313	103	7	±	±	NUM
dti-1313	103	8	s.e.m	s.e.m	NOUN
dti-1313	103	9	.	.	PUNCT
dti-1313	104	1	*	*	PUNCT
dti-1313	104	2	:	:	PUNCT
dti-1313	104	3	p	p	X
dti-1313	104	4	<	<	X
dti-1313	104	5	0.05	0.05	NUM
dti-1313	104	6	,	,	PUNCT
dti-1313	104	7	*	*	PUNCT
dti-1313	104	8	*	*	PUNCT
dti-1313	104	9	:	:	PUNCT
dti-1313	104	10	p	p	X
dti-1313	104	11	<	<	X
dti-1313	104	12	0.01	0.01	NUM
dti-1313	104	13	,	,	PUNCT
dti-1313	104	14	*	*	PUNCT
dti-1313	104	15	*	*	PUNCT
dti-1313	104	16	*	*	PUNCT
dti-1313	104	17	:	:	PUNCT
dti-1313	104	18	p	p	X
dti-1313	104	19	<	<	X
dti-1313	104	20	0.001	0.001	NUM
dti-1313	104	21	,	,	PUNCT
dti-1313	104	22	with	with	ADP
dti-1313	104	23	respect	respect	NOUN
dti-1313	104	24	to	to	ADP
dti-1313	104	25	control	control	NOUN
dti-1313	104	26	value	value	NOUN
dti-1313	104	27	.	.	PUNCT
dti-1313	105	1	satoh	satoh	NOUN
dti-1313	105	2	et	et	NOUN
dti-1313	105	3	al.indd	al.indd	X
dti-1313	105	4	4	4	NUM
dti-1313	105	5	5/14/2007	5/14/2007	NUM
dti-1313	105	6	8:59:10	8:59:10	PROPN
dti-1313	105	7	pm	pm	NOUN
dti-1313	105	8	100	100	NUM
dti-1313	105	9	cardiovascular	cardiovascular	ADJ
dti-1313	105	10	pharmacology	pharmacology	NOUN
dti-1313	105	11	of	of	ADP
dti-1313	105	12	sinomenine	sinomenine	NOUN
dti-1313	105	13	drug	drug	NOUN
dti-1313	105	14	target	target	NOUN
dti-1313	105	15	insights	insight	NOUN
dti-1313	105	16	2007	2007	NUM
dti-1313	105	17	:	:	PUNCT
dti-1313	105	18	2	2	NUM
dti-1313	105	19	synovial	synovial	ADJ
dti-1313	105	20	fibroblasts	fibroblast	NOUN
dti-1313	105	21	in	in	ADP
dti-1313	105	22	rat	rat	NOUN
dti-1313	105	23	adjuvant	adjuvant	ADJ
dti-1313	105	24	arthritis	arthritis	NOUN
dti-1313	105	25	models	model	NOUN
dti-1313	105	26	(	(	PUNCT
dti-1313	105	27	liu	liu	PROPN
dti-1313	105	28	et	et	PROPN
dti-1313	105	29	al	al	PROPN
dti-1313	105	30	.	.	PROPN
dti-1313	105	31	1996	1996	NUM
dti-1313	105	32	)	)	PUNCT
dti-1313	105	33	.	.	PUNCT
dti-1313	106	1	the	the	DET
dti-1313	106	2	anti	anti	ADJ
dti-1313	106	3	-	-	ADJ
dti-1313	106	4	infl	infl	ADJ
dti-1313	106	5	ammatory	ammatory	NOUN
dti-1313	106	6	and	and	CCONJ
dti-1313	106	7	immunomodulative	immunomodulative	ADJ
dti-1313	106	8	actions	action	NOUN
dti-1313	106	9	of	of	ADP
dti-1313	106	10	sinomenine	sinomenine	NOUN
dti-1313	106	11	are	be	AUX
dti-1313	106	12	responsible	responsible	ADJ
dti-1313	106	13	for	for	ADP
dti-1313	106	14	various	various	ADJ
dti-1313	106	15	mechanisms	mechanism	NOUN
dti-1313	106	16	via	via	ADP
dti-1313	106	17	complex	complex	ADJ
dti-1313	106	18	modulation	modulation	NOUN
dti-1313	106	19	of	of	ADP
dti-1313	106	20	leukocytes	leukocyte	NOUN
dti-1313	106	21	and	and	CCONJ
dti-1313	106	22	cytokine	cytokine	ADJ
dti-1313	106	23	.	.	PUNCT
dti-1313	107	1	sinomenine	sinomenine	NOUN
dti-1313	107	2	reduces	reduce	VERB
dti-1313	107	3	the	the	DET
dti-1313	107	4	production	production	NOUN
dti-1313	107	5	of	of	ADP
dti-1313	107	6	prostagrandin	prostagrandin	NOUN
dti-1313	107	7	(	(	PUNCT
dti-1313	107	8	pg	pg	NOUN
dti-1313	107	9	)	)	PUNCT
dti-1313	107	10	e2	e2	PROPN
dti-1313	107	11	and	and	CCONJ
dti-1313	107	12	no	no	ADV
dti-1313	107	13	from	from	ADP
dti-1313	107	14	macrophage	macrophage	NOUN
dti-1313	107	15	(	(	PUNCT
dti-1313	107	16	liu	liu	PROPN
dti-1313	107	17	et	et	PROPN
dti-1313	107	18	al	al	PROPN
dti-1313	107	19	.	.	PROPN
dti-1313	107	20	1994a	1994a	NUM
dti-1313	107	21	)	)	PUNCT
dti-1313	107	22	.	.	PUNCT
dti-1313	108	1	also	also	ADV
dti-1313	108	2	,	,	PUNCT
dti-1313	108	3	sinomenine	sinomenine	NOUN
dti-1313	108	4	possesses	possess	VERB
dti-1313	108	5	anti	anti	ADJ
dti-1313	108	6	-	-	ADJ
dti-1313	108	7	proliferative	proliferative	ADJ
dti-1313	108	8	effects	effect	NOUN
dti-1313	108	9	on	on	ADP
dti-1313	108	10	lymphocytes	lymphocyte	NOUN
dti-1313	108	11	(	(	PUNCT
dti-1313	108	12	liu	liu	PROPN
dti-1313	108	13	et	et	PROPN
dti-1313	108	14	al	al	PROPN
dti-1313	108	15	.	.	PROPN
dti-1313	108	16	1994b	1994b	NUM
dti-1313	108	17	)	)	PUNCT
dti-1313	108	18	,	,	PUNCT
dti-1313	108	19	contributing	contribute	VERB
dti-1313	108	20	to	to	ADP
dti-1313	108	21	anti	anti	ADJ
dti-1313	108	22	-	-	ADJ
dti-1313	108	23	infl	infl	ADJ
dti-1313	108	24	ammatory	ammatory	NOUN
dti-1313	108	25	and	and	CCONJ
dti-1313	108	26	anti	anti	ADJ
dti-1313	108	27	-	-	ADJ
dti-1313	108	28	rheumatic	rheumatic	ADJ
dti-1313	108	29	effects	effect	NOUN
dti-1313	108	30	.	.	PUNCT
dti-1313	109	1	in	in	ADP
dti-1313	109	2	addition	addition	NOUN
dti-1313	109	3	,	,	PUNCT
dti-1313	109	4	sinomenine	sinomenine	NOUN
dti-1313	109	5	depressed	depressed	ADJ
dti-1313	109	6	mrna	mrna	NOUN
dti-1313	109	7	expression	expression	NOUN
dti-1313	109	8	of	of	ADP
dti-1313	109	9	tumor	tumor	NOUN
dti-1313	109	10	necrosis	necrosis	NOUN
dti-1313	109	11	factor	factor	NOUN
dti-1313	109	12	(	(	PUNCT
dti-1313	109	13	tnf)-α	tnf)-α	NOUN
dti-1313	109	14	and	and	CCONJ
dti-1313	109	15	interleukin	interleukin	NOUN
dti-1313	109	16	(	(	PUNCT
dti-1313	109	17	il)-β	il)-β	X
dti-1313	109	18	of	of	ADP
dti-1313	109	19	peritoneal	peritoneal	ADJ
dti-1313	109	20	macrophages	macrophage	NOUN
dti-1313	109	21	(	(	PUNCT
dti-1313	109	22	wang	wang	PROPN
dti-1313	109	23	et	et	PROPN
dti-1313	109	24	al	al	PROPN
dti-1313	109	25	.	.	PROPN
dti-1313	109	26	2005	2005	NUM
dti-1313	109	27	)	)	PUNCT
dti-1313	109	28	.	.	PUNCT
dti-1313	110	1	therefore	therefore	ADV
dti-1313	110	2	,	,	PUNCT
dti-1313	110	3	sinomenine	sinomenine	NOUN
dti-1313	110	4	may	may	AUX
dti-1313	110	5	act	act	VERB
dti-1313	110	6	as	as	ADP
dti-1313	110	7	an	an	DET
dti-1313	110	8	anti	anti	ADJ
dti-1313	110	9	-	-	ADJ
dti-1313	110	10	rheumatic	rheumatic	ADJ
dti-1313	110	11	drug	drug	NOUN
dti-1313	110	12	through	through	ADP
dti-1313	110	13	the	the	DET
dti-1313	110	14	anti	anti	ADJ
dti-1313	110	15	-	-	ADJ
dti-1313	110	16	infl	infl	ADJ
dti-1313	110	17	ammatory	ammatory	NOUN
dti-1313	110	18	effects	effect	NOUN
dti-1313	110	19	on	on	ADP
dti-1313	110	20	lymphocytes	lymphocyte	NOUN
dti-1313	110	21	and	and	CCONJ
dti-1313	110	22	cytokine	cytokine	ADJ
dti-1313	110	23	.	.	PUNCT
dti-1313	111	1	sinomenine	sinomenine	PROPN
dti-1313	111	2	inhibited	inhibit	VERB
dti-1313	111	3	bfgf	bfgf	ADV
dti-1313	111	4	-	-	PUNCT
dti-1313	111	5	induced	induce	VERB
dti-1313	111	6	angiogenesis	angiogenesis	NOUN
dti-1313	111	7	in	in	ADP
dti-1313	111	8	vitro	vitro	X
dti-1313	111	9	and	and	CCONJ
dti-1313	111	10	in	in	ADP
dti-1313	111	11	vivo	vivo	NOUN
dti-1313	111	12	(	(	PUNCT
dti-1313	111	13	kok	kok	PROPN
dti-1313	111	14	et	et	PROPN
dti-1313	111	15	al	al	PROPN
dti-1313	111	16	.	.	PROPN
dti-1313	111	17	2005	2005	NUM
dti-1313	111	18	)	)	PUNCT
dti-1313	111	19	.	.	PUNCT
dti-1313	112	1	sinomenine	sinomenine	PROPN
dti-1313	112	2	also	also	ADV
dti-1313	112	3	attenuates	attenuate	VERB
dti-1313	112	4	transmigration	transmigration	NOUN
dti-1313	112	5	of	of	ADP
dti-1313	112	6	granulocyte	granulocyte	NOUN
dti-1313	112	7	.	.	PUNCT
dti-1313	113	1	the	the	DET
dti-1313	113	2	inhibition	inhibition	NOUN
dti-1313	113	3	of	of	ADP
dti-1313	113	4	leukocytes	leukocyte	NOUN
dti-1313	113	5	migration	migration	NOUN
dti-1313	113	6	across	across	ADP
dti-1313	113	7	the	the	DET
dti-1313	113	8	vessel	vessel	NOUN
dti-1313	113	9	wall	wall	NOUN
dti-1313	113	10	and	and	CCONJ
dti-1313	113	11	anti	anti	ADJ
dti-1313	113	12	-	-	ADJ
dti-1313	113	13	angiogeneic	angiogeneic	ADJ
dti-1313	113	14	effect	effect	NOUN
dti-1313	113	15	of	of	ADP
dti-1313	113	16	sinomenine	sinomenine	NOUN
dti-1313	113	17	may	may	AUX
dti-1313	113	18	also	also	ADV
dti-1313	113	19	contribute	contribute	VERB
dti-1313	113	20	to	to	ADP
dti-1313	113	21	therapeutic	therapeutic	ADJ
dti-1313	113	22	effects	effect	NOUN
dti-1313	113	23	for	for	ADP
dti-1313	113	24	ra	ra	PROPN
dti-1313	113	25	.	.	PUNCT
dti-1313	114	1	immunomodulative	immunomodulative	PROPN
dti-1313	114	2	actions	action	NOUN
dti-1313	114	3	have	have	AUX
dti-1313	114	4	been	be	AUX
dti-1313	114	5	studied	study	VERB
dti-1313	114	6	as	as	ADP
dti-1313	114	7	the	the	DET
dti-1313	114	8	other	other	ADJ
dti-1313	114	9	aspect	aspect	NOUN
dti-1313	114	10	of	of	ADP
dti-1313	114	11	sinomenine	sinomenine	NOUN
dti-1313	114	12	concerning	concern	VERB
dti-1313	114	13	about	about	ADP
dti-1313	114	14	the	the	DET
dti-1313	114	15	cardiac	cardiac	ADJ
dti-1313	114	16	transplantation	transplantation	NOUN
dti-1313	114	17	model	model	NOUN
dti-1313	114	18	.	.	PUNCT
dti-1313	115	1	it	it	PRON
dti-1313	115	2	has	have	AUX
dti-1313	115	3	been	be	AUX
dti-1313	115	4	reported	report	VERB
dti-1313	115	5	that	that	SCONJ
dti-1313	115	6	acute	acute	ADJ
dti-1313	115	7	and	and	CCONJ
dti-1313	115	8	chronic	chronic	ADJ
dti-1313	115	9	cardiac	cardiac	ADJ
dti-1313	115	10	allograft	allograft	NOUN
dti-1313	115	11	ejections	ejection	NOUN
dti-1313	115	12	are	be	AUX
dti-1313	115	13	blocked	block	VERB
dti-1313	115	14	by	by	ADP
dti-1313	115	15	the	the	DET
dti-1313	115	16	immunomodulatory	immunomodulatory	ADJ
dti-1313	115	17	effects	effect	NOUN
dti-1313	115	18	of	of	ADP
dti-1313	115	19	sinomenine	sinomenine	NOUN
dti-1313	115	20	(	(	PUNCT
dti-1313	115	21	mark	mark	NOUN
dti-1313	115	22	et	et	PROPN
dti-1313	115	23	al	al	PROPN
dti-1313	115	24	.	.	PROPN
dti-1313	115	25	2003	2003	NUM
dti-1313	115	26	)	)	PUNCT
dti-1313	115	27	.	.	PUNCT
dti-1313	116	1	conclusion	conclusion	NOUN
dti-1313	116	2	endothelium	endothelium	NOUN
dti-1313	116	3	-	-	PUNCT
dti-1313	116	4	dependent	dependent	ADJ
dti-1313	116	5	and	and	CCONJ
dti-1313	116	6	-independent	-independent	ADJ
dti-1313	116	7	relaxations	relaxation	NOUN
dti-1313	116	8	we	we	PRON
dti-1313	116	9	have	have	AUX
dti-1313	116	10	been	be	AUX
dti-1313	116	11	demonstrated	demonstrate	VERB
dti-1313	116	12	that	that	SCONJ
dti-1313	116	13	sinomenine	sinomenine	NOUN
dti-1313	116	14	possesses	possess	VERB
dti-1313	116	15	strong	strong	ADJ
dti-1313	116	16	vasodilating	vasodilate	VERB
dti-1313	116	17	actions	action	NOUN
dti-1313	116	18	by	by	ADP
dti-1313	116	19	multiple	multiple	ADJ
dti-1313	116	20	mechanisms	mechanism	NOUN
dti-1313	116	21	(	(	PUNCT
dti-1313	116	22	nishida	nishida	NOUN
dti-1313	116	23	and	and	CCONJ
dti-1313	116	24	satoh	satoh	NOUN
dti-1313	116	25	,	,	PUNCT
dti-1313	116	26	2006	2006	NUM
dti-1313	116	27	)	)	PUNCT
dti-1313	116	28	.	.	PUNCT
dti-1313	117	1	the	the	DET
dti-1313	117	2	summarized	summarize	VERB
dti-1313	117	3	mechanisms	mechanism	NOUN
dti-1313	117	4	of	of	ADP
dti-1313	117	5	sinomenine	sinomenine	NOUN
dti-1313	117	6	-	-	PUNCT
dti-1313	117	7	induced	induce	VERB
dti-1313	117	8	vasorelaxation	vasorelaxation	NOUN
dti-1313	117	9	are	be	AUX
dti-1313	117	10	shown	show	VERB
dti-1313	117	11	in	in	ADP
dti-1313	117	12	fig	fig	NOUN
dti-1313	117	13	.	.	PUNCT
dti-1313	118	1	3	3	X
dti-1313	118	2	.	.	NOUN
dti-1313	118	3	sinomenine	sinomenine	NOUN
dti-1313	118	4	possesses	possess	VERB
dti-1313	118	5	endothelium	endothelium	NOUN
dti-1313	118	6	-	-	PUNCT
dti-1313	118	7	dependent	dependent	ADJ
dti-1313	118	8	vasorelaxation	vasorelaxation	NOUN
dti-1313	118	9	via	via	ADP
dti-1313	118	10	no	no	DET
dti-1313	118	11	and	and	CCONJ
dti-1313	118	12	pgi2	pgi2	PROPN
dti-1313	118	13	releasing	release	VERB
dti-1313	118	14	from	from	ADP
dti-1313	118	15	endothelium	endothelium	NOUN
dti-1313	118	16	.	.	PUNCT
dti-1313	119	1	nos	no	NOUN
dti-1313	119	2	activation	activation	NOUN
dti-1313	119	3	and	and	CCONJ
dti-1313	119	4	pgi2	pgi2	PROPN
dti-1313	119	5	release	release	NOUN
dti-1313	119	6	are	be	AUX
dti-1313	119	7	elicited	elicit	VERB
dti-1313	119	8	by	by	ADP
dti-1313	119	9	an	an	DET
dti-1313	119	10	increase	increase	NOUN
dti-1313	119	11	in	in	ADP
dti-1313	119	12	the	the	DET
dti-1313	119	13	intracellular	intracellular	ADJ
dti-1313	119	14	ca2	ca2	PROPN
dti-1313	119	15	+	+	NOUN
dti-1313	119	16	concentration	concentration	NOUN
dti-1313	119	17	(	(	PUNCT
dti-1313	119	18	[	[	X
dti-1313	119	19	ca2+]i	ca2+]i	NOUN
dti-1313	119	20	)	)	PUNCT
dti-1313	119	21	in	in	ADP
dti-1313	119	22	endothelium	endothelium	NOUN
dti-1313	119	23	cells	cell	NOUN
dti-1313	119	24	(	(	PUNCT
dti-1313	119	25	busse	busse	PROPN
dti-1313	119	26	et	et	PROPN
dti-1313	119	27	al	al	PROPN
dti-1313	119	28	.	.	PROPN
dti-1313	119	29	1998	1998	NUM
dti-1313	119	30	;	;	PUNCT
dti-1313	119	31	quignard	quignard	PROPN
dti-1313	119	32	et	et	PROPN
dti-1313	119	33	al	al	PROPN
dti-1313	119	34	.	.	PROPN
dti-1313	119	35	1999	1999	NUM
dti-1313	119	36	)	)	PUNCT
dti-1313	119	37	.	.	PUNCT
dti-1313	120	1	the	the	DET
dti-1313	120	2	mechanisms	mechanism	NOUN
dti-1313	120	3	for	for	ADP
dti-1313	120	4	the	the	DET
dti-1313	120	5	endothelium	endothelium	NOUN
dti-1313	120	6	-	-	PUNCT
dti-1313	120	7	dependent	dependent	ADJ
dti-1313	120	8	relaxations	relaxation	NOUN
dti-1313	120	9	are	be	AUX
dti-1313	120	10	not	not	PART
dti-1313	120	11	yet	yet	ADV
dti-1313	120	12	unclear	unclear	ADJ
dti-1313	120	13	.	.	PUNCT
dti-1313	121	1	however	however	ADV
dti-1313	121	2	,	,	PUNCT
dti-1313	121	3	sinomenine	sinomenine	NOUN
dti-1313	121	4	might	might	AUX
dti-1313	121	5	increase	increase	VERB
dti-1313	121	6	[	[	X
dti-1313	121	7	ca2+]i	ca2+]i	NOUN
dti-1313	121	8	in	in	ADP
dti-1313	121	9	endothelium	endothelium	NOUN
dti-1313	121	10	cells	cell	NOUN
dti-1313	121	11	and	and	CCONJ
dti-1313	121	12	then	then	ADV
dti-1313	121	13	,	,	PUNCT
dti-1313	121	14	activates	activate	VERB
dti-1313	121	15	figure	figure	NOUN
dti-1313	121	16	3	3	NUM
dti-1313	121	17	.	.	PUNCT
dti-1313	122	1	summary	summary	NOUN
dti-1313	122	2	of	of	ADP
dti-1313	122	3	the	the	DET
dti-1313	122	4	multiple	multiple	ADJ
dti-1313	122	5	mechanisms	mechanism	NOUN
dti-1313	122	6	induced	induce	VERB
dti-1313	122	7	by	by	ADP
dti-1313	122	8	sinomenine	sinomenine	NOUN
dti-1313	122	9	.	.	PUNCT
dti-1313	123	1	sinomenine	sinomenine	NOUN
dti-1313	123	2	produces	produce	VERB
dti-1313	123	3	the	the	DET
dti-1313	123	4	vasorelaxation	vasorelaxation	NOUN
dti-1313	123	5	via	via	ADP
dti-1313	123	6	no	no	DET
dti-1313	123	7	and	and	CCONJ
dti-1313	123	8	pgi2	pgi2	PROPN
dti-1313	123	9	releasings	releasing	NOUN
dti-1313	123	10	from	from	ADP
dti-1313	123	11	endothelium	endothelium	NOUN
dti-1313	123	12	.	.	PUNCT
dti-1313	124	1	also	also	ADV
dti-1313	124	2	,	,	PUNCT
dti-1313	124	3	sinomenine	sinomenine	NOUN
dti-1313	124	4	causes	cause	VERB
dti-1313	124	5	the	the	DET
dti-1313	124	6	vasorelaxation	vasorelaxation	NOUN
dti-1313	124	7	via	via	ADP
dti-1313	124	8	modulation	modulation	NOUN
dti-1313	124	9	of	of	ADP
dti-1313	124	10	ca2	ca2	PROPN
dti-1313	124	11	+	+	NOUN
dti-1313	124	12	channels	channel	NOUN
dti-1313	124	13	and	and	CCONJ
dti-1313	124	14	pk	pk	NOUN
dti-1313	124	15	-	-	PUNCT
dti-1313	124	16	c	c	NOUN
dti-1313	124	17	activity	activity	NOUN
dti-1313	124	18	in	in	ADP
dti-1313	124	19	smooth	smooth	ADJ
dti-1313	124	20	muscle	muscle	NOUN
dti-1313	124	21	cells	cell	NOUN
dti-1313	124	22	.	.	PUNCT
dti-1313	125	1	in	in	ADP
dti-1313	125	2	addition	addition	NOUN
dti-1313	125	3	,	,	PUNCT
dti-1313	125	4	β	β	X
dti-1313	125	5	-	-	PUNCT
dti-1313	125	6	adrenoceptor	adrenoceptor	NOUN
dti-1313	125	7	stimulation	stimulation	NOUN
dti-1313	125	8	is	be	AUX
dti-1313	125	9	caused	cause	VERB
dti-1313	125	10	.	.	PUNCT
dti-1313	126	1	nos	nos	X
dti-1313	126	2	:	:	PUNCT
dti-1313	126	3	nitric	nitric	ADJ
dti-1313	126	4	oxide	oxide	NOUN
dti-1313	126	5	synthetase	synthetase	NOUN
dti-1313	126	6	,	,	PUNCT
dti-1313	126	7	pk	pk	NOUN
dti-1313	126	8	-	-	ADJ
dti-1313	126	9	c	c	NOUN
dti-1313	126	10	:	:	PUNCT
dti-1313	126	11	protein	protein	NOUN
dti-1313	126	12	kinase	kinase	PROPN
dti-1313	126	13	c	c	X
dti-1313	126	14	,	,	PUNCT
dti-1313	126	15	pgi2	pgi2	PROPN
dti-1313	126	16	:	:	PUNCT
dti-1313	126	17	prostaglandin	prostaglandin	NOUN
dti-1313	126	18	i2	i2	PROPN
dti-1313	126	19	.	.	PUNCT
dti-1313	127	1	satoh	satoh	PROPN
dti-1313	127	2	et	et	PROPN
dti-1313	127	3	al.indd	al.indd	X
dti-1313	127	4	5	5	NUM
dti-1313	127	5	5/14/2007	5/14/2007	NUM
dti-1313	127	6	8:59:10	8:59:10	PROPN
dti-1313	127	7	pm	pm	NOUN
dti-1313	127	8	101	101	NUM
dti-1313	127	9	nishida	nishida	ADJ
dti-1313	127	10	and	and	CCONJ
dti-1313	127	11	satoh	satoh	NOUN
dti-1313	127	12	drug	drug	NOUN
dti-1313	127	13	target	target	NOUN
dti-1313	127	14	insights	insight	NOUN
dti-1313	127	15	2007	2007	NUM
dti-1313	127	16	:	:	PUNCT
dti-1313	127	17	2	2	NUM
dti-1313	127	18	nos	nos	NOUN
dti-1313	127	19	activity	activity	NOUN
dti-1313	127	20	and	and	CCONJ
dti-1313	127	21	pgi2	pgi2	PROPN
dti-1313	127	22	releasing	releasing	NOUN
dti-1313	127	23	,	,	PUNCT
dti-1313	127	24	as	as	SCONJ
dti-1313	127	25	reported	report	VERB
dti-1313	127	26	previously	previously	ADV
dti-1313	127	27	(	(	PUNCT
dti-1313	127	28	nishida	nishida	ADJ
dti-1313	127	29	and	and	CCONJ
dti-1313	127	30	satoh	satoh	NOUN
dti-1313	127	31	,	,	PUNCT
dti-1313	127	32	2003	2003	NUM
dti-1313	127	33	)	)	PUNCT
dti-1313	127	34	.	.	PUNCT
dti-1313	128	1	sinomenine	sinomenine	NOUN
dti-1313	128	2	causes	cause	VERB
dti-1313	128	3	the	the	DET
dti-1313	128	4	vasorelaxation	vasorelaxation	NOUN
dti-1313	128	5	via	via	ADP
dti-1313	128	6	modulation	modulation	NOUN
dti-1313	128	7	of	of	ADP
dti-1313	128	8	ca2	ca2	PROPN
dti-1313	128	9	+	+	NOUN
dti-1313	128	10	channels	channel	NOUN
dti-1313	128	11	and	and	CCONJ
dti-1313	128	12	pk	pk	NOUN
dti-1313	128	13	-	-	PUNCT
dti-1313	128	14	c	c	NOUN
dti-1313	128	15	activity	activity	NOUN
dti-1313	128	16	in	in	ADP
dti-1313	128	17	vascular	vascular	ADJ
dti-1313	128	18	smooth	smooth	ADJ
dti-1313	128	19	muscle	muscle	NOUN
dti-1313	128	20	cells	cell	NOUN
dti-1313	128	21	.	.	PUNCT
dti-1313	129	1	in	in	ADP
dti-1313	129	2	vascular	vascular	ADJ
dti-1313	129	3	muscle	muscle	NOUN
dti-1313	129	4	cells	cell	NOUN
dti-1313	129	5	,	,	PUNCT
dti-1313	129	6	the	the	DET
dti-1313	129	7	contraction	contraction	NOUN
dti-1313	129	8	systems	system	NOUN
dti-1313	129	9	and	and	CCONJ
dti-1313	129	10	the	the	DET
dti-1313	129	11	ion	ion	NOUN
dti-1313	129	12	channels	channel	NOUN
dti-1313	129	13	are	be	AUX
dti-1313	129	14	regulated	regulate	VERB
dti-1313	129	15	through	through	ADP
dti-1313	129	16	the	the	DET
dti-1313	129	17	intracellular	intracellular	ADJ
dti-1313	129	18	signal	signal	NOUN
dti-1313	129	19	conditions	condition	NOUN
dti-1313	129	20	(	(	PUNCT
dti-1313	129	21	satoh	satoh	NOUN
dti-1313	129	22	and	and	CCONJ
dti-1313	129	23	sperelakis	sperelakis	PROPN
dti-1313	129	24	,	,	PUNCT
dti-1313	129	25	1991	1991	NUM
dti-1313	129	26	,	,	PUNCT
dti-1313	129	27	1995	1995	NUM
dti-1313	129	28	;	;	PUNCT
dti-1313	129	29	satoh	satoh	NOUN
dti-1313	129	30	,	,	PUNCT
dti-1313	129	31	1996	1996	NUM
dti-1313	129	32	)	)	PUNCT
dti-1313	129	33	.	.	PUNCT
dti-1313	130	1	therefore	therefore	ADV
dti-1313	130	2	,	,	PUNCT
dti-1313	130	3	sinomenine	sinomenine	NOUN
dti-1313	130	4	might	might	AUX
dti-1313	130	5	modulate	modulate	VERB
dti-1313	130	6	the	the	DET
dti-1313	130	7	contraction	contraction	NOUN
dti-1313	130	8	systems	system	NOUN
dti-1313	130	9	,	,	PUNCT
dti-1313	130	10	ca2	ca2	PROPN
dti-1313	130	11	+	+	PROPN
dti-1313	130	12	and	and	CCONJ
dti-1313	130	13	na+	na+	NOUN
dti-1313	130	14	channels	channel	NOUN
dti-1313	130	15	,	,	PUNCT
dti-1313	130	16	delayed	delay	VERB
dti-1313	130	17	rectifi	rectifi	NOUN
dti-1313	130	18	er	er	INTJ
dti-1313	130	19	k+	k+	NOUN
dti-1313	130	20	channels	channel	NOUN
dti-1313	130	21	,	,	PUNCT
dti-1313	130	22	and	and	CCONJ
dti-1313	130	23	ca2	ca2	PROPN
dti-1313	130	24	+	+	PROPN
dti-1313	130	25	-activated	-activated	ADJ
dti-1313	130	26	k+	k+	NOUN
dti-1313	130	27	(	(	PUNCT
dti-1313	130	28	kca	kca	PROPN
dti-1313	130	29	)	)	PUNCT
dti-1313	130	30	channel	channel	PROPN
dti-1313	130	31	,	,	PUNCT
dti-1313	130	32	accompanied	accompany	VERB
dti-1313	130	33	with	with	ADP
dti-1313	130	34	the	the	DET
dti-1313	130	35	activation	activation	NOUN
dti-1313	130	36	of	of	ADP
dti-1313	130	37	pk	pk	NOUN
dti-1313	130	38	-	-	NOUN
dti-1313	130	39	c	c	NOUN
dti-1313	130	40	(	(	PUNCT
dti-1313	130	41	nishida	nishida	NOUN
dti-1313	130	42	and	and	CCONJ
dti-1313	130	43	satoh	satoh	NOUN
dti-1313	130	44	,	,	PUNCT
dti-1313	130	45	2007	2007	NUM
dti-1313	130	46	)	)	PUNCT
dti-1313	130	47	.	.	PUNCT
dti-1313	131	1	also	also	ADV
dti-1313	131	2	,	,	PUNCT
dti-1313	131	3	sinomenine	sinomenine	NOUN
dti-1313	131	4	possesses	possesse	NOUN
dti-1313	131	5	β	β	NOUN
dti-1313	131	6	-	-	PUNCT
dti-1313	131	7	adrenoceptor	adrenoceptor	NOUN
dti-1313	131	8	stimulating	stimulate	VERB
dti-1313	131	9	action	action	NOUN
dti-1313	131	10	to	to	PART
dti-1313	131	11	inhibit	inhibit	VERB
dti-1313	131	12	the	the	DET
dti-1313	131	13	aortic	aortic	ADJ
dti-1313	131	14	constriction	constriction	NOUN
dti-1313	131	15	.	.	PUNCT
dti-1313	132	1	clinically	clinically	ADV
dti-1313	132	2	possibility	possibility	NOUN
dti-1313	132	3	of	of	ADP
dti-1313	132	4	cardiovascular	cardiovascular	ADJ
dti-1313	132	5	pharmacological	pharmacological	ADJ
dti-1313	132	6	effects	effect	NOUN
dti-1313	132	7	sinomenine	sinomenine	NOUN
dti-1313	132	8	is	be	AUX
dti-1313	132	9	included	include	VERB
dti-1313	132	10	in	in	ADP
dti-1313	132	11	sinomenine	sinomenine	NOUN
dti-1313	132	12	acutum	acutum	NOUN
dti-1313	132	13	of	of	ADP
dti-1313	132	14	mokuboito	mokuboito	PROPN
dti-1313	132	15	.	.	PUNCT
dti-1313	133	1	mokuboito	mokuboito	PROPN
dti-1313	133	2	is	be	AUX
dti-1313	133	3	traditionally	traditionally	ADV
dti-1313	133	4	used	use	VERB
dti-1313	133	5	for	for	ADP
dti-1313	133	6	dyspnea	dyspnea	NOUN
dti-1313	133	7	and	and	CCONJ
dti-1313	133	8	edema	edema	PROPN
dti-1313	133	9	(	(	PUNCT
dti-1313	133	10	shuji	shuji	PROPN
dti-1313	133	11	et	et	PROPN
dti-1313	133	12	al	al	PROPN
dti-1313	133	13	.	.	PROPN
dti-1313	133	14	2002	2002	NUM
dti-1313	133	15	)	)	PUNCT
dti-1313	133	16	.	.	PUNCT
dti-1313	134	1	therefore	therefore	ADV
dti-1313	134	2	,	,	PUNCT
dti-1313	134	3	sinomenine	sinomenine	NOUN
dti-1313	134	4	may	may	AUX
dti-1313	134	5	be	be	AUX
dti-1313	134	6	expected	expect	VERB
dti-1313	134	7	as	as	ADP
dti-1313	134	8	one	one	NUM
dti-1313	134	9	of	of	ADP
dti-1313	134	10	the	the	DET
dti-1313	134	11	therapeutic	therapeutic	ADJ
dti-1313	134	12	agents	agent	NOUN
dti-1313	134	13	for	for	ADP
dti-1313	134	14	heart	heart	NOUN
dti-1313	134	15	failure	failure	NOUN
dti-1313	134	16	.	.	PUNCT
dti-1313	135	1	most	most	ADV
dti-1313	135	2	recently	recently	ADV
dti-1313	135	3	,	,	PUNCT
dti-1313	135	4	satoh	satoh	NOUN
dti-1313	135	5	(	(	PUNCT
dti-1313	135	6	2005	2005	NUM
dti-1313	135	7	)	)	PUNCT
dti-1313	135	8	has	have	AUX
dti-1313	135	9	demonstrated	demonstrate	VERB
dti-1313	135	10	that	that	DET
dti-1313	135	11	sinomenine	sinomenine	NOUN
dti-1313	135	12	effectively	effectively	ADV
dti-1313	135	13	modulates	modulate	VERB
dti-1313	135	14	cardiac	cardiac	ADJ
dti-1313	135	15	ionic	ionic	ADJ
dti-1313	135	16	channels	channel	NOUN
dti-1313	135	17	.	.	PUNCT
dti-1313	136	1	sinomenine	sinomenine	NOUN
dti-1313	136	2	inhibits	inhibit	VERB
dti-1313	136	3	ica	ica	PROPN
dti-1313	136	4	,	,	PUNCT
dti-1313	136	5	and	and	CCONJ
dti-1313	136	6	simultaneously	simultaneously	ADV
dti-1313	136	7	produces	produce	VERB
dti-1313	136	8	the	the	DET
dti-1313	136	9	ik	ik	PROPN
dti-1313	136	10	decerease	decerease	PROPN
dti-1313	136	11	in	in	ADP
dti-1313	136	12	cardiomyocytes	cardiomyocyte	NOUN
dti-1313	136	13	which	which	PRON
dti-1313	136	14	results	result	VERB
dti-1313	136	15	in	in	ADP
dti-1313	136	16	the	the	DET
dti-1313	136	17	apd	apd	PROPN
dti-1313	136	18	prolongation	prolongation	PROPN
dti-1313	136	19	.	.	PUNCT
dti-1313	137	1	modulation	modulation	NOUN
dti-1313	137	2	of	of	ADP
dti-1313	137	3	ca2	ca2	PROPN
dti-1313	137	4	+	+	PROPN
dti-1313	137	5	channel	channel	NOUN
dti-1313	137	6	induced	induce	VERB
dti-1313	137	7	by	by	ADP
dti-1313	137	8	sinomenine	sinomenine	NOUN
dti-1313	137	9	is	be	AUX
dti-1313	137	10	similarly	similarly	ADV
dti-1313	137	11	exerted	exert	VERB
dti-1313	137	12	in	in	ADP
dti-1313	137	13	vascular	vascular	ADJ
dti-1313	137	14	smooth	smooth	ADJ
dti-1313	137	15	muscle	muscle	NOUN
dti-1313	137	16	cells	cell	NOUN
dti-1313	137	17	.	.	PUNCT
dti-1313	138	1	in	in	ADP
dti-1313	138	2	addition	addition	NOUN
dti-1313	138	3	,	,	PUNCT
dti-1313	138	4	sinomenine	sinomenine	NOUN
dti-1313	138	5	possesses	possess	VERB
dti-1313	138	6	the	the	DET
dti-1313	138	7	regulatory	regulatory	ADJ
dti-1313	138	8	actions	action	NOUN
dti-1313	138	9	for	for	ADP
dti-1313	138	10	dysrhythmias	dysrhythmia	NOUN
dti-1313	138	11	under	under	ADP
dti-1313	138	12	ca2	ca2	PROPN
dti-1313	138	13	+	+	PROPN
dti-1313	138	14	overload	overload	NOUN
dti-1313	138	15	conditions	condition	NOUN
dti-1313	138	16	.	.	PUNCT
dti-1313	139	1	it	it	PRON
dti-1313	139	2	has	have	AUX
dti-1313	139	3	been	be	AUX
dti-1313	139	4	well	well	ADV
dti-1313	139	5	known	know	VERB
dti-1313	139	6	that	that	SCONJ
dti-1313	139	7	under	under	ADP
dti-1313	139	8	the	the	DET
dti-1313	139	9	ischemia	ischemia	NOUN
dti-1313	139	10	and	and	CCONJ
dti-1313	139	11	heart	heart	NOUN
dti-1313	139	12	failure	failure	NOUN
dti-1313	139	13	,	,	PUNCT
dti-1313	139	14	the	the	DET
dti-1313	139	15	cellular	cellular	ADJ
dti-1313	139	16	ca2	ca2	PROPN
dti-1313	139	17	+	+	PROPN
dti-1313	139	18	overload	overload	NOUN
dti-1313	139	19	of	of	ADP
dti-1313	139	20	heart	heart	NOUN
dti-1313	139	21	muscles	muscle	NOUN
dti-1313	139	22	elicits	elicit	VERB
dti-1313	139	23	some	some	DET
dti-1313	139	24	arrhythmias	arrhythmia	NOUN
dti-1313	139	25	and	and	CCONJ
dti-1313	139	26	dysfunctions	dysfunction	NOUN
dti-1313	139	27	(	(	PUNCT
dti-1313	139	28	satoh	satoh	NOUN
dti-1313	139	29	,	,	PUNCT
dti-1313	139	30	2001	2001	NUM
dti-1313	139	31	;	;	PUNCT
dti-1313	139	32	2003	2003	NUM
dti-1313	139	33	)	)	PUNCT
dti-1313	139	34	.	.	PUNCT
dti-1313	140	1	the	the	DET
dti-1313	140	2	regulation	regulation	NOUN
dti-1313	140	3	of	of	ADP
dti-1313	140	4	ca2	ca2	PROPN
dti-1313	140	5	+	+	PROPN
dti-1313	140	6	infl	infl	PROPN
dti-1313	140	7	ux	ux	PROPN
dti-1313	140	8	may	may	AUX
dti-1313	140	9	modulate	modulate	VERB
dti-1313	140	10	ca2	ca2	PROPN
dti-1313	140	11	+	+	PROPN
dti-1313	140	12	overload	overload	NOUN
dti-1313	140	13	in	in	ADP
dti-1313	140	14	cardiomyocytes	cardiomyocyte	NOUN
dti-1313	140	15	and	and	CCONJ
dti-1313	140	16	produces	produce	VERB
dti-1313	140	17	protective	protective	ADJ
dti-1313	140	18	actions	action	NOUN
dti-1313	140	19	for	for	ADP
dti-1313	140	20	ca2	ca2	PROPN
dti-1313	140	21	+	+	PROPN
dti-1313	140	22	-overloaded	-overloaded	ADJ
dti-1313	140	23	myocardial	myocardial	ADJ
dti-1313	140	24	cells	cell	NOUN
dti-1313	140	25	(	(	PUNCT
dti-1313	140	26	satoh	satoh	NOUN
dti-1313	140	27	and	and	CCONJ
dti-1313	140	28	spererakis	spereraki	NOUN
dti-1313	140	29	,	,	PUNCT
dti-1313	140	30	1998	1998	NUM
dti-1313	140	31	)	)	PUNCT
dti-1313	140	32	.	.	PUNCT
dti-1313	141	1	therefore	therefore	ADV
dti-1313	141	2	,	,	PUNCT
dti-1313	141	3	sinomenine	sinomenine	NOUN
dti-1313	141	4	might	might	AUX
dti-1313	141	5	restrain	restrain	VERB
dti-1313	141	6	the	the	DET
dti-1313	141	7	cell	cell	NOUN
dti-1313	141	8	damages	damage	NOUN
dti-1313	141	9	of	of	ADP
dti-1313	141	10	heart	heart	NOUN
dti-1313	141	11	muscles	muscle	NOUN
dti-1313	141	12	via	via	ADP
dti-1313	141	13	modulation	modulation	NOUN
dti-1313	141	14	of	of	ADP
dti-1313	141	15	[	[	X
dti-1313	141	16	ca2+]i	ca2+]i	NOUN
dti-1313	141	17	,	,	PUNCT
dti-1313	141	18	and	and	CCONJ
dti-1313	141	19	as	as	ADP
dti-1313	141	20	a	a	DET
dti-1313	141	21	result	result	NOUN
dti-1313	141	22	,	,	PUNCT
dti-1313	141	23	exert	exert	VERB
dti-1313	141	24	a	a	DET
dti-1313	141	25	cardioprotective	cardioprotective	ADJ
dti-1313	141	26	action	action	NOUN
dti-1313	141	27	.	.	PUNCT
dti-1313	142	1	cardiopotective	cardiopotective	ADJ
dti-1313	142	2	action	action	NOUN
dti-1313	142	3	of	of	ADP
dti-1313	142	4	sinomenine	sinomenine	NOUN
dti-1313	142	5	on	on	ADP
dti-1313	142	6	rat	rat	NOUN
dti-1313	142	7	acute	acute	ADJ
dti-1313	142	8	myocardial	myocardial	ADJ
dti-1313	142	9	ischemia	ischemia	NOUN
dti-1313	142	10	has	have	AUX
dti-1313	142	11	also	also	ADV
dti-1313	142	12	been	be	AUX
dti-1313	142	13	demonstrated	demonstrate	VERB
dti-1313	142	14	.	.	PUNCT
dti-1313	143	1	reperfusion	reperfusion	NOUN
dti-1313	143	2	injury	injury	NOUN
dti-1313	143	3	is	be	AUX
dti-1313	143	4	induced	induce	VERB
dti-1313	143	5	by	by	ADP
dti-1313	143	6	ligating	ligate	VERB
dti-1313	143	7	the	the	DET
dti-1313	143	8	rat	rat	NOUN
dti-1313	143	9	left	leave	VERB
dti-1313	143	10	coronary	coronary	ADJ
dti-1313	143	11	artery	artery	NOUN
dti-1313	143	12	for	for	ADP
dti-1313	143	13	15	15	NUM
dti-1313	143	14	min	min	NOUN
dti-1313	143	15	and	and	CCONJ
dti-1313	143	16	reopening	reopening	NOUN
dti-1313	143	17	.	.	PUNCT
dti-1313	144	1	sinomenine	sinomenine	NOUN
dti-1313	144	2	can	can	AUX
dti-1313	144	3	inhibit	inhibit	VERB
dti-1313	144	4	the	the	DET
dti-1313	144	5	incidence	incidence	NOUN
dti-1313	144	6	of	of	ADP
dti-1313	144	7	b	b	NOUN
dti-1313	144	8	a	a	DET
dti-1313	144	9	figure	figure	NOUN
dti-1313	144	10	4	4	NUM
dti-1313	144	11	.	.	PUNCT
dti-1313	144	12	modulation	modulation	NOUN
dti-1313	144	13	by	by	ADP
dti-1313	144	14	sinomenine	sinomenine	NOUN
dti-1313	144	15	on	on	ADP
dti-1313	144	16	the	the	DET
dti-1313	144	17	action	action	NOUN
dti-1313	144	18	potentials	potential	VERB
dti-1313	144	19	in	in	ADP
dti-1313	144	20	guinea	guinea	NOUN
dti-1313	144	21	pig	pig	NOUN
dti-1313	144	22	ventricular	ventricular	ADJ
dti-1313	144	23	cardiomyocytes	cardiomyocyte	NOUN
dti-1313	144	24	.	.	PUNCT
dti-1313	145	1	a	a	DET
dti-1313	145	2	:	:	PUNCT
dti-1313	145	3	concentration	concentration	NOUN
dti-1313	145	4	-	-	PUNCT
dti-1313	145	5	dependent	dependent	ADJ
dti-1313	145	6	changes	change	NOUN
dti-1313	145	7	in	in	ADP
dti-1313	145	8	the	the	DET
dti-1313	145	9	action	action	NOUN
dti-1313	145	10	potential	potential	ADJ
dti-1313	145	11	confi	confi	NOUN
dti-1313	145	12	guration	guration	NOUN
dti-1313	145	13	by	by	ADP
dti-1313	145	14	sinomenine	sinomenine	NOUN
dti-1313	145	15	.	.	PUNCT
dti-1313	146	1	short	short	ADJ
dti-1313	146	2	lines	line	NOUN
dti-1313	146	3	at	at	ADP
dti-1313	146	4	the	the	DET
dti-1313	146	5	left	left	NOUN
dti-1313	146	6	of	of	ADP
dti-1313	146	7	action	action	NOUN
dti-1313	146	8	potential	potential	ADJ
dti-1313	146	9	recordings	recording	NOUN
dti-1313	146	10	represent	represent	VERB
dti-1313	146	11	zero	zero	NUM
dti-1313	146	12	mv	mv	NOUN
dti-1313	146	13	level	level	NOUN
dti-1313	146	14	.	.	PUNCT
dti-1313	147	1	b	b	X
dti-1313	147	2	:	:	PUNCT
dti-1313	147	3	the	the	DET
dti-1313	147	4	percentage	percentage	NOUN
dti-1313	147	5	inhibitions	inhibition	NOUN
dti-1313	147	6	by	by	ADP
dti-1313	147	7	sinomenine	sinomenine	NOUN
dti-1313	147	8	of	of	ADP
dti-1313	147	9	cardiac	cardiac	ADJ
dti-1313	147	10	ionic	ionic	ADJ
dti-1313	147	11	currents	current	NOUN
dti-1313	147	12	.	.	PUNCT
dti-1313	148	1	vertical	vertical	ADJ
dti-1313	148	2	bars	bar	NOUN
dti-1313	148	3	represent	represent	VERB
dti-1313	148	4	mean	mean	PROPN
dti-1313	148	5	±	±	NUM
dti-1313	148	6	sem	sem	PROPN
dti-1313	148	7	.	.	PUNCT
dti-1313	149	1	figure	figure	NOUN
dti-1313	149	2	5	5	NUM
dti-1313	149	3	.	.	PUNCT
dti-1313	150	1	antiarrhythmic	antiarrhythmic	ADJ
dti-1313	150	2	actions	action	NOUN
dti-1313	150	3	of	of	ADP
dti-1313	150	4	sinomenine	sinomenine	NOUN
dti-1313	150	5	in	in	ADP
dti-1313	150	6	guinea	guinea	NOUN
dti-1313	150	7	pig	pig	NOUN
dti-1313	150	8	papillary	papillary	ADJ
dti-1313	150	9	muscles	muscle	NOUN
dti-1313	150	10	.	.	PUNCT
dti-1313	151	1	sinomenine	sinomenine	PROPN
dti-1313	151	2	abolishes	abolish	VERB
dti-1313	151	3	the	the	DET
dti-1313	151	4	abnormal	abnormal	ADJ
dti-1313	151	5	action	action	NOUN
dti-1313	151	6	potentials	potential	VERB
dti-1313	151	7	in	in	ADP
dti-1313	151	8	high	high	ADJ
dti-1313	151	9	ca2	ca2	PROPN
dti-1313	151	10	+	+	PROPN
dti-1313	151	11	concentration	concentration	NOUN
dti-1313	151	12	(	(	PUNCT
dti-1313	151	13	5.4	5.4	NUM
dti-1313	151	14	mm	mm	NOUN
dti-1313	151	15	)	)	PUNCT
dti-1313	151	16	.	.	PUNCT
dti-1313	152	1	dots	dot	NOUN
dti-1313	152	2	above	above	ADP
dti-1313	152	3	the	the	DET
dti-1313	152	4	action	action	NOUN
dti-1313	152	5	potential	potential	ADJ
dti-1313	152	6	recordings	recording	NOUN
dti-1313	152	7	are	be	AUX
dti-1313	152	8	represented	represent	VERB
dti-1313	152	9	the	the	DET
dti-1313	152	10	regular	regular	ADJ
dti-1313	152	11	rhythms	rhythm	NOUN
dti-1313	152	12	induced	induce	VERB
dti-1313	152	13	by	by	ADP
dti-1313	152	14	1	1	NUM
dti-1313	152	15	hz	hz	VERB
dti-1313	152	16	stimulation	stimulation	NOUN
dti-1313	152	17	.	.	PUNCT
dti-1313	153	1	the	the	DET
dti-1313	153	2	horizontal	horizontal	ADJ
dti-1313	153	3	line	line	NOUN
dti-1313	153	4	indicates	indicate	VERB
dti-1313	153	5	zero	zero	NUM
dti-1313	153	6	mv	mv	NOUN
dti-1313	153	7	.	.	PUNCT
dti-1313	154	1	satoh	satoh	PROPN
dti-1313	154	2	et	et	PROPN
dti-1313	154	3	al.indd	al.indd	X
dti-1313	154	4	6	6	NUM
dti-1313	154	5	5/14/2007	5/14/2007	NUM
dti-1313	154	6	8:59:10	8:59:10	PROPN
dti-1313	154	7	pm	pm	NOUN
dti-1313	154	8	102	102	NUM
dti-1313	154	9	cardiovascular	cardiovascular	ADJ
dti-1313	154	10	pharmacology	pharmacology	NOUN
dti-1313	154	11	of	of	ADP
dti-1313	154	12	sinomenine	sinomenine	NOUN
dti-1313	154	13	drug	drug	NOUN
dti-1313	154	14	target	target	NOUN
dti-1313	154	15	insights	insight	NOUN
dti-1313	154	16	2007	2007	NUM
dti-1313	154	17	:	:	SYM
dti-1313	154	18	2	2	NUM
dti-1313	154	19	arrhythmias	arrhythmia	NOUN
dti-1313	154	20	and	and	CCONJ
dti-1313	154	21	reduce	reduce	VERB
dti-1313	154	22	intracellular	intracellular	ADJ
dti-1313	154	23	ca2	ca2	NOUN
dti-1313	154	24	+	+	NOUN
dti-1313	154	25	concentration	concentration	NOUN
dti-1313	154	26	(	(	PUNCT
dti-1313	154	27	xie	xie	PROPN
dti-1313	154	28	et	et	PROPN
dti-1313	154	29	al	al	PROPN
dti-1313	154	30	.	.	PROPN
dti-1313	154	31	1993	1993	NUM
dti-1313	154	32	)	)	PUNCT
dti-1313	154	33	,	,	PUNCT
dti-1313	154	34	well	well	ADV
dti-1313	154	35	consistent	consistent	ADJ
dti-1313	154	36	with	with	ADP
dti-1313	154	37	our	our	PRON
dti-1313	154	38	results	result	NOUN
dti-1313	154	39	.	.	PUNCT
dti-1313	155	1	sinomenine	sinomenine	NOUN
dti-1313	155	2	has	have	VERB
dti-1313	155	3	multiple	multiple	ADJ
dti-1313	155	4	vasodilating	vasodilate	VERB
dti-1313	155	5	mechanisms	mechanism	NOUN
dti-1313	155	6	.	.	PUNCT
dti-1313	156	1	the	the	DET
dti-1313	156	2	vasodilating	vasodilate	VERB
dti-1313	156	3	agent	agent	NOUN
dti-1313	156	4	is	be	AUX
dti-1313	156	5	one	one	NUM
dti-1313	156	6	of	of	ADP
dti-1313	156	7	the	the	DET
dti-1313	156	8	great	great	ADJ
dti-1313	156	9	useful	useful	ADJ
dti-1313	156	10	tools	tool	NOUN
dti-1313	156	11	for	for	ADP
dti-1313	156	12	heart	heart	NOUN
dti-1313	156	13	failure	failure	NOUN
dti-1313	156	14	and	and	CCONJ
dti-1313	156	15	regulates	regulate	VERB
dti-1313	156	16	preand	preand	NOUN
dti-1313	156	17	afterloads	afterload	NOUN
dti-1313	156	18	of	of	ADP
dti-1313	156	19	cardiovascular	cardiovascular	ADJ
dti-1313	156	20	systems	system	NOUN
dti-1313	156	21	.	.	PUNCT
dti-1313	157	1	therefore	therefore	ADV
dti-1313	157	2	,	,	PUNCT
dti-1313	157	3	sinomenine	sinomenine	NOUN
dti-1313	157	4	-	-	PUNCT
dti-1313	157	5	induced	induce	VERB
dti-1313	157	6	vasodilating	vasodilate	VERB
dti-1313	157	7	actions	action	NOUN
dti-1313	157	8	may	may	AUX
dti-1313	157	9	improve	improve	VERB
dti-1313	157	10	cardiac	cardiac	ADJ
dti-1313	157	11	functions	function	NOUN
dti-1313	157	12	via	via	ADP
dti-1313	157	13	the	the	DET
dti-1313	157	14	regulation	regulation	NOUN
dti-1313	157	15	of	of	ADP
dti-1313	157	16	both	both	DET
dti-1313	157	17	preand	preand	NOUN
dti-1313	157	18	after	after	ADP
dti-1313	157	19	-	-	PUNCT
dti-1313	157	20	loads	load	NOUN
dti-1313	157	21	under	under	ADP
dti-1313	157	22	heart	heart	NOUN
dti-1313	157	23	failure	failure	NOUN
dti-1313	157	24	.	.	PUNCT
dti-1313	158	1	in	in	ADP
dti-1313	158	2	summary	summary	NOUN
dti-1313	158	3	,	,	PUNCT
dti-1313	158	4	sinomenine	sinomenine	NOUN
dti-1313	158	5	caused	cause	VERB
dti-1313	158	6	a	a	DET
dti-1313	158	7	concentrationdependent	concentrationdependent	NOUN
dti-1313	158	8	vasorelaxation	vasorelaxation	NOUN
dti-1313	158	9	on	on	ADP
dti-1313	158	10	ne-	ne-	PROPN
dti-1313	158	11	,	,	PUNCT
dti-1313	158	12	kcland	kcland	PROPN
dti-1313	158	13	pdb	pdb	PROPN
dti-1313	158	14	-	-	ADJ
dti-1313	158	15	induced	induce	VERB
dti-1313	158	16	contractions	contraction	NOUN
dti-1313	158	17	,	,	PUNCT
dti-1313	158	18	and	and	CCONJ
dti-1313	158	19	sinomenineinduced	sinomenineinduced	ADJ
dti-1313	158	20	vasorelaxation	vasorelaxation	NOUN
dti-1313	158	21	is	be	AUX
dti-1313	158	22	attenuated	attenuate	VERB
dti-1313	158	23	by	by	ADP
dti-1313	158	24	the	the	DET
dti-1313	158	25	pretreatments	pretreatment	NOUN
dti-1313	158	26	with	with	ADP
dti-1313	158	27	l	l	PROPN
dti-1313	158	28	-	-	NOUN
dti-1313	158	29	nmma	nmma	PROPN
dti-1313	158	30	,	,	PUNCT
dti-1313	158	31	indomethacin	indomethacin	PROPN
dti-1313	158	32	,	,	PUNCT
dti-1313	158	33	staurosporine	staurosporine	NOUN
dti-1313	158	34	,	,	PUNCT
dti-1313	158	35	nicardipine	nicardipine	NOUN
dti-1313	158	36	and	and	CCONJ
dti-1313	158	37	propranolol	propranolol	NOUN
dti-1313	158	38	.	.	PUNCT
dti-1313	159	1	in	in	ADP
dti-1313	159	2	electropharmacological	electropharmacological	ADJ
dti-1313	159	3	mechanisms	mechanism	NOUN
dti-1313	159	4	,	,	PUNCT
dti-1313	159	5	sinomenine	sinomenine	NOUN
dti-1313	159	6	inhibits	inhibit	VERB
dti-1313	159	7	the	the	DET
dti-1313	159	8	ica	ica	PROPN
dti-1313	159	9	and	and	CCONJ
dti-1313	159	10	the	the	DET
dti-1313	159	11	ik	ik	PROPN
dti-1313	159	12	in	in	ADP
dti-1313	159	13	cardiomyocytes	cardiomyocyte	NOUN
dti-1313	159	14	which	which	PRON
dti-1313	159	15	results	result	VERB
dti-1313	159	16	in	in	ADP
dti-1313	159	17	the	the	DET
dti-1313	159	18	apd	apd	PROPN
dti-1313	159	19	prolongation	prolongation	NOUN
dti-1313	159	20	.	.	PUNCT
dti-1313	160	1	in	in	ADP
dti-1313	160	2	addition	addition	NOUN
dti-1313	160	3	,	,	PUNCT
dti-1313	160	4	sinomenine	sinomenine	NOUN
dti-1313	160	5	depressed	depress	VERB
dti-1313	160	6	the	the	DET
dti-1313	160	7	dysrhysmias	dysrhysmia	NOUN
dti-1313	160	8	induced	induce	VERB
dti-1313	160	9	by	by	ADP
dti-1313	160	10	triggered	trigger	VERB
dti-1313	160	11	activities	activity	NOUN
dti-1313	160	12	under	under	ADP
dti-1313	160	13	the	the	DET
dti-1313	160	14	ca2	ca2	PROPN
dti-1313	160	15	+	+	PROPN
dti-1313	160	16	overload	overload	NOUN
dti-1313	160	17	.	.	PUNCT
dti-1313	161	1	finally	finally	ADV
dti-1313	161	2	,	,	PUNCT
dti-1313	161	3	sinomenine	sinomenine	NOUN
dti-1313	161	4	also	also	ADV
dti-1313	161	5	possesses	possess	VERB
dti-1313	161	6	the	the	DET
dti-1313	161	7	antiinfl	antiinfl	NOUN
dti-1313	161	8	ammatory	ammatory	NOUN
dti-1313	161	9	and	and	CCONJ
dti-1313	161	10	immunomodulative	immunomodulative	ADJ
dti-1313	161	11	actions	action	NOUN
dti-1313	161	12	.	.	PUNCT
dti-1313	162	1	in	in	ADP
dti-1313	162	2	future	future	NOUN
dti-1313	162	3	,	,	PUNCT
dti-1313	162	4	therefore	therefore	ADV
dti-1313	162	5	,	,	PUNCT
dti-1313	162	6	sinomenine	sinomenine	NOUN
dti-1313	162	7	as	as	SCONJ
dti-1313	162	8	a	a	DET
dti-1313	162	9	cardioprotective	cardioprotective	ADJ
dti-1313	162	10	drug	drug	NOUN
dti-1313	162	11	may	may	AUX
dti-1313	162	12	be	be	AUX
dti-1313	162	13	expected	expect	VERB
dti-1313	162	14	to	to	ADP
dti-1313	162	15	the	the	DET
dti-1313	162	16	respectable	respectable	ADJ
dti-1313	162	17	effectiveness	effectiveness	NOUN
dti-1313	162	18	for	for	ADP
dti-1313	162	19	heart	heart	NOUN
dti-1313	162	20	failure	failure	NOUN
dti-1313	162	21	,	,	PUNCT
dti-1313	162	22	mediated	mediate	VERB
dti-1313	162	23	through	through	ADP
dti-1313	162	24	the	the	DET
dti-1313	162	25	modulation	modulation	NOUN
dti-1313	162	26	of	of	ADP
dti-1313	162	27	cardiac	cardiac	ADJ
dti-1313	162	28	ion	ion	NOUN
dti-1313	162	29	channels	channel	NOUN
dti-1313	162	30	(	(	PUNCT
dti-1313	162	31	including	include	VERB
dti-1313	162	32	the	the	DET
dti-1313	162	33	regulation	regulation	NOUN
dti-1313	162	34	for	for	ADP
dti-1313	162	35	dysrhythmias	dysrhythmia	NOUN
dti-1313	162	36	)	)	PUNCT
dti-1313	162	37	and	and	CCONJ
dti-1313	162	38	blood	blood	NOUN
dti-1313	162	39	vessels	vessel	NOUN
dti-1313	162	40	.	.	PUNCT
dti-1313	163	1	further	further	ADJ
dti-1313	163	2	experiments	experiment	NOUN
dti-1313	163	3	need	need	VERB
dti-1313	163	4	to	to	PART
dti-1313	163	5	elucidate	elucidate	VERB
dti-1313	163	6	more	more	ADV
dti-1313	163	7	in	in	ADP
dti-1313	163	8	detail	detail	NOUN
dti-1313	163	9	mechanisms	mechanism	NOUN
dti-1313	163	10	of	of	ADP
dti-1313	163	11	sinomenine	sinomenine	NOUN
dti-1313	163	12	.	.	PUNCT
dti-1313	164	1	acknowledgements	acknowledgement	NOUN
dti-1313	164	2	the	the	DET
dti-1313	164	3	authors	author	NOUN
dti-1313	164	4	wish	wish	VERB
dti-1313	164	5	to	to	PART
dti-1313	164	6	express	express	VERB
dti-1313	164	7	thanks	thank	NOUN
dti-1313	164	8	for	for	ADP
dti-1313	164	9	the	the	DET
dti-1313	164	10	supply	supply	NOUN
dti-1313	164	11	of	of	ADP
dti-1313	164	12	mokuboito	mokuboito	PROPN
dti-1313	164	13	and	and	CCONJ
dti-1313	164	14	sinomenium	sinomenium	ADJ
dti-1313	164	15	acutum	acutum	NOUN
dti-1313	164	16	extracts	extract	NOUN
dti-1313	164	17	(	(	PUNCT
dti-1313	164	18	tsumura	tsumura	PROPN
dti-1313	164	19	co.	co.	PROPN
dti-1313	164	20	)	)	PUNCT
dti-1313	164	21	.	.	PUNCT
dti-1313	165	1	this	this	DET
dti-1313	165	2	work	work	NOUN
dti-1313	165	3	was	be	AUX
dti-1313	165	4	in	in	ADP
dti-1313	165	5	part	part	NOUN
dti-1313	165	6	supported	support	VERB
dti-1313	165	7	by	by	ADP
dti-1313	165	8	the	the	DET
dti-1313	165	9	research	research	NOUN
dti-1313	165	10	fund	fund	NOUN
dti-1313	165	11	of	of	ADP
dti-1313	165	12	japan	japan	PROPN
dti-1313	165	13	kampo	kampo	PROPN
dti-1313	165	14	medicine	medicine	PROPN
dti-1313	165	15	manufactures	manufacture	VERB
dti-1313	165	16	association	association	PROPN
dti-1313	165	17	.	.	PUNCT
dti-1313	166	1	references	reference	NOUN
dti-1313	166	2	busse	busse	PROPN
dti-1313	166	3	,	,	PUNCT
dti-1313	166	4	r.	r.	PROPN
dti-1313	166	5	,	,	PUNCT
dti-1313	166	6	fichter	fichter	NOUN
dti-1313	166	7	,	,	PUNCT
dti-1313	166	8	h.	h.	PROPN
dti-1313	166	9	,	,	PUNCT
dti-1313	166	10	luckhoff	luckhoff	ADJ
dti-1313	166	11	,	,	PUNCT
dti-1313	166	12	a.	a.	PROPN
dti-1313	166	13	et	et	PROPN
dti-1313	166	14	al	al	PROPN
dti-1313	166	15	.	.	PROPN
dti-1313	166	16	1998	1998	NUM
dti-1313	166	17	.	.	PUNCT
dti-1313	167	1	hyperpolarizaion	hyperpolarizaion	NOUN
dti-1313	167	2	and	and	CCONJ
dti-1313	167	3	increased	increase	VERB
dti-1313	167	4	free	free	ADJ
dti-1313	167	5	calcium	calcium	NOUN
dti-1313	167	6	in	in	ADP
dti-1313	167	7	acethylcholine	acethylcholine	ADV
dti-1313	167	8	-	-	PUNCT
dti-1313	167	9	stimulated	stimulated	ADJ
dti-1313	167	10	endothelium	endothelium	NOUN
dti-1313	167	11	cells	cell	NOUN
dti-1313	167	12	.	.	PUNCT
dti-1313	168	1	am	be	AUX
dti-1313	168	2	.	.	PUNCT
dti-1313	169	1	j.	j.	PROPN
dti-1313	169	2	physiol	physiol	PROPN
dti-1313	169	3	.	.	PUNCT
dti-1313	169	4	,	,	PUNCT
dti-1313	169	5	255	255	NUM
dti-1313	169	6	:	:	PUNCT
dti-1313	169	7	h965–9	h965–9	PROPN
dti-1313	169	8	.	.	PUNCT
dti-1313	170	1	inaki	inaki	NOUN
dti-1313	170	2	,	,	PUNCT
dti-1313	170	3	k.	k.	PROPN
dti-1313	170	4	2005	2005	NUM
dti-1313	170	5	.	.	PUNCT
dti-1313	171	1	diseases	disease	NOUN
dti-1313	171	2	and	and	CCONJ
dti-1313	171	3	kampo	kampo	NOUN
dti-1313	171	4	.	.	PUNCT
dti-1313	172	1	in	in	ADP
dti-1313	172	2	sato	sato	PROPN
dti-1313	172	3	,	,	PUNCT
dti-1313	172	4	y.	y.	PROPN
dti-1313	172	5	,	,	PUNCT
dti-1313	172	6	hanawa	hanawa	PROPN
dti-1313	172	7	,	,	PUNCT
dti-1313	172	8	t.	t.	PROPN
dti-1313	172	9	,	,	PUNCT
dti-1313	172	10	arai	arai	PROPN
dti-1313	172	11	,	,	PUNCT
dti-1313	172	12	m.	m.	NOUN
dti-1313	172	13	,	,	PUNCT
dti-1313	172	14	cyong	cyong	PROPN
dti-1313	172	15	,	,	PUNCT
dti-1313	172	16	j.	j.	PROPN
dti-1313	172	17	,	,	PUNCT
dti-1313	172	18	fukuzawa	fukuzawa	NOUN
dti-1313	172	19	,	,	PUNCT
dti-1313	172	20	m.	m.	NOUN
dti-1313	172	21	,	,	PUNCT
dti-1313	172	22	mitani	mitani	PROPN
dti-1313	172	23	,	,	PUNCT
dti-1313	172	24	k.	k.	PROPN
dti-1313	172	25	,	,	PUNCT
dti-1313	172	26	ogihara	ogihara	PROPN
dti-1313	172	27	,	,	PUNCT
dti-1313	172	28	y.	y.	PROPN
dti-1313	172	29	,	,	PUNCT
dti-1313	172	30	sakiyama	sakiyama	PROPN
dti-1313	172	31	,	,	PUNCT
dti-1313	172	32	t.	t.	PROPN
dti-1313	172	33	,	,	PUNCT
dti-1313	172	34	shimada	shimada	PROPN
dti-1313	172	35	,	,	PUNCT
dti-1313	172	36	y.	y.	PROPN
dti-1313	172	37	,	,	PUNCT
dti-1313	172	38	toriizuka	toriizuka	PROPN
dti-1313	172	39	,	,	PUNCT
dti-1313	172	40	k.	k.	PROPN
dti-1313	172	41	,	,	PUNCT
dti-1313	172	42	ymamada	ymamada	PROPN
dti-1313	172	43	,	,	PUNCT
dti-1313	172	44	t.	t.	PROPN
dti-1313	172	45	ed	ed	PROPN
dti-1313	172	46	.	.	PUNCT
dti-1313	173	1	introduction	introduction	NOUN
dti-1313	173	2	to	to	PART
dti-1313	173	3	kampo	kampo	PROPN
dti-1313	173	4	.	.	PUNCT
dti-1313	174	1	elsevier	elsevier	PROPN
dti-1313	174	2	japan	japan	PROPN
dti-1313	174	3	.	.	PUNCT
dti-1313	175	1	p125	p125	PROPN
dti-1313	175	2	.	.	PUNCT
dti-1313	176	1	kok	kok	PROPN
dti-1313	176	2	,	,	PUNCT
dti-1313	176	3	t.w	t.w	PROPN
dti-1313	176	4	.	.	PROPN
dti-1313	176	5	,	,	PUNCT
dti-1313	176	6	yue	yue	PROPN
dti-1313	176	7	,	,	PUNCT
dti-1313	176	8	p.y	p.y	PROPN
dti-1313	176	9	.	.	PROPN
dti-1313	176	10	,	,	PUNCT
dti-1313	176	11	mak	mak	PROPN
dti-1313	176	12	,	,	PUNCT
dti-1313	176	13	n.k	n.k	PROPN
dti-1313	176	14	.	.	PROPN
dti-1313	176	15	et	et	PROPN
dti-1313	176	16	al	al	PROPN
dti-1313	176	17	.	.	PROPN
dti-1313	176	18	2005	2005	NUM
dti-1313	176	19	.	.	PUNCT
dti-1313	177	1	the	the	DET
dti-1313	177	2	anti	anti	ADJ
dti-1313	177	3	-	-	ADJ
dti-1313	177	4	angiogenic	angiogenic	ADJ
dti-1313	177	5	effect	effect	NOUN
dti-1313	177	6	of	of	ADP
dti-1313	177	7	sinomenine	sinomenine	NOUN
dti-1313	177	8	.	.	PUNCT
dti-1313	178	1	angiogenesis	angiogenesis	NOUN
dti-1313	178	2	,	,	PUNCT
dti-1313	178	3	8(1):3–12	8(1):3–12	NUM
dti-1313	178	4	.	.	PUNCT
dti-1313	179	1	kubota	kubota	PROPN
dti-1313	179	2	,	,	PUNCT
dti-1313	179	3	y.	y.	PROPN
dti-1313	179	4	,	,	PUNCT
dti-1313	179	5	tanaka	tanaka	PROPN
dti-1313	179	6	,	,	PUNCT
dti-1313	179	7	t.	t.	PROPN
dti-1313	179	8	and	and	CCONJ
dti-1313	179	9	umegaki	umegaki	ADJ
dti-1313	179	10	,	,	PUNCT
dti-1313	179	11	k.	k.	PROPN
dti-1313	179	12	2001	2001	NUM
dti-1313	179	13	.	.	PUNCT
dti-1313	180	1	ginkgo	ginkgo	NOUN
dti-1313	180	2	biloba	biloba	NOUN
dti-1313	180	3	extract	extract	NOUN
dti-1313	180	4	-	-	PUNCT
dti-1313	180	5	induced	induce	VERB
dti-1313	180	6	relaxation	relaxation	NOUN
dti-1313	180	7	of	of	ADP
dti-1313	180	8	rat	rat	NOUN
dti-1313	180	9	aorta	aorta	NOUN
dti-1313	180	10	is	be	AUX
dti-1313	180	11	associated	associate	VERB
dti-1313	180	12	with	with	ADP
dti-1313	180	13	increase	increase	NOUN
dti-1313	180	14	in	in	ADP
dti-1313	180	15	endothelial	endothelial	ADJ
dti-1313	180	16	intracellular	intracellular	ADJ
dti-1313	180	17	calcium	calcium	NOUN
dti-1313	180	18	level	level	NOUN
dti-1313	180	19	.	.	PUNCT
dti-1313	181	1	life	life	NOUN
dti-1313	181	2	sci	sci	PROPN
dti-1313	181	3	.	.	PROPN
dti-1313	181	4	,	,	PUNCT
dti-1313	181	5	69:2327–36	69:2327–36	NUM
dti-1313	181	6	.	.	PUNCT
dti-1313	182	1	li	li	PROPN
dti-1313	182	2	,	,	PUNCT
dti-1313	182	3	r.w	r.w	PROPN
dti-1313	182	4	.	.	PROPN
dti-1313	182	5	,	,	PUNCT
dti-1313	182	6	david	david	PROPN
dti-1313	182	7	,	,	PUNCT
dti-1313	182	8	lin	lin	PROPN
dti-1313	182	9	,	,	PUNCT
dti-1313	182	10	g.	g.	PROPN
dti-1313	182	11	,	,	PUNCT
dti-1313	182	12	myers	myers	PROPN
dti-1313	182	13	,	,	PUNCT
dti-1313	182	14	s.p	s.p	PROPN
dti-1313	182	15	.	.	PROPN
dti-1313	182	16	et	et	PROPN
dti-1313	182	17	al	al	PROPN
dti-1313	182	18	.	.	PROPN
dti-1313	182	19	2003	2003	NUM
dti-1313	182	20	.	.	PUNCT
dti-1313	183	1	anti	anti	ADJ
dti-1313	183	2	-	-	ADJ
dti-1313	183	3	inflammatory	inflammatory	ADJ
dti-1313	183	4	activity	activity	NOUN
dti-1313	183	5	of	of	ADP
dti-1313	183	6	chinese	chinese	ADJ
dti-1313	183	7	medical	medical	ADJ
dti-1313	183	8	vine	vine	NOUN
dti-1313	183	9	plants	plant	NOUN
dti-1313	183	10	.	.	PUNCT
dti-1313	184	1	j.	j.	PROPN
dti-1313	184	2	ethnopharmacol	ethnopharmacol	PROPN
dti-1313	184	3	.	.	PUNCT
dti-1313	185	1	85(1):61–7	85(1):61–7	NUM
dti-1313	185	2	.	.	PUNCT
dti-1313	186	1	li	li	PROPN
dti-1313	186	2	,	,	PUNCT
dti-1313	186	3	y.	y.	PROPN
dti-1313	186	4	,	,	PUNCT
dti-1313	186	5	cui	cui	PROPN
dti-1313	186	6	,	,	PUNCT
dti-1313	186	7	s.	s.	PROPN
dti-1313	186	8	,	,	PUNCT
dti-1313	186	9	cheng	cheng	PROPN
dti-1313	186	10	,	,	PUNCT
dti-1313	186	11	y.	y.	PROPN
dti-1313	186	12	et	et	PROPN
dti-1313	186	13	al	al	PROPN
dti-1313	186	14	.	.	PROPN
dti-1313	186	15	2004	2004	NUM
dti-1313	186	16	.	.	PUNCT
dti-1313	187	1	application	application	NOUN
dti-1313	187	2	of	of	ADP
dti-1313	187	3	nonaqueous	nonaqueous	ADJ
dti-1313	187	4	capillary	capillary	ADJ
dti-1313	187	5	electrophoresis	electrophoresis	NOUN
dti-1313	187	6	for	for	ADP
dti-1313	187	7	quantitative	quantitative	ADJ
dti-1313	187	8	analysis	analysis	NOUN
dti-1313	187	9	of	of	ADP
dti-1313	187	10	quinolizidine	quinolizidine	ADJ
dti-1313	187	11	alkaloids	alkaloid	NOUN
dti-1313	187	12	in	in	ADP
dti-1313	187	13	chinese	chinese	ADJ
dti-1313	187	14	herbs	herb	NOUN
dti-1313	187	15	.	.	PUNCT
dti-1313	188	1	anal	anal	PROPN
dti-1313	188	2	.	.	PUNCT
dti-1313	189	1	chim	chim	PROPN
dti-1313	189	2	.	.	PUNCT
dti-1313	190	1	acta	acta	PROPN
dti-1313	190	2	.	.	PROPN
dti-1313	190	3	,	,	PUNCT
dti-1313	191	1	508:17–22	508:17–22	X
dti-1313	191	2	.	.	PUNCT
dti-1313	191	3	liu	liu	PROPN
dti-1313	191	4	,	,	PUNCT
dti-1313	191	5	l.	l.	PROPN
dti-1313	191	6	,	,	PUNCT
dti-1313	191	7	riese	riese	PROPN
dti-1313	191	8	,	,	PUNCT
dti-1313	191	9	j.	j.	PROPN
dti-1313	191	10	,	,	PUNCT
dti-1313	191	11	resch	resch	PROPN
dti-1313	191	12	,	,	PUNCT
dti-1313	191	13	k.	k.	PROPN
dti-1313	191	14	et	et	PROPN
dti-1313	191	15	al	al	PROPN
dti-1313	191	16	.	.	PROPN
dti-1313	191	17	1994	1994	NUM
dti-1313	191	18	(	(	PUNCT
dti-1313	191	19	a	a	NOUN
dti-1313	191	20	)	)	PUNCT
dti-1313	191	21	.	.	PUNCT
dti-1313	192	1	impairment	impairment	NOUN
dti-1313	192	2	of	of	ADP
dti-1313	192	3	macropharge	macropharge	NOUN
dti-1313	192	4	eicosanoids	eicosanoid	NOUN
dti-1313	192	5	and	and	CCONJ
dti-1313	192	6	nitric	nitric	ADJ
dti-1313	192	7	oxide	oxide	NOUN
dti-1313	192	8	production	production	NOUN
dti-1313	192	9	by	by	ADP
dti-1313	192	10	alkaloid	alkaloid	PROPN
dti-1313	192	11	from	from	ADP
dti-1313	192	12	sinomenium	sinomenium	PROPN
dti-1313	192	13	acutum	acutum	PROPN
dti-1313	192	14	.	.	PUNCT
dti-1313	193	1	arzneimittelforschung	arzneimittelforschung	PROPN
dti-1313	193	2	,	,	PUNCT
dti-1313	193	3	44:1223–26	44:1223–26	NUM
dti-1313	193	4	.	.	PUNCT
dti-1313	194	1	liu	liu	PROPN
dti-1313	194	2	,	,	PUNCT
dti-1313	194	3	l.	l.	PROPN
dti-1313	194	4	,	,	PUNCT
dti-1313	194	5	resch	resch	PROPN
dti-1313	194	6	,	,	PUNCT
dti-1313	194	7	k.	k.	PROPN
dti-1313	194	8	,	,	PUNCT
dti-1313	194	9	and	and	CCONJ
dti-1313	194	10	kaever	kaever	NOUN
dti-1313	194	11	,	,	PUNCT
dti-1313	194	12	v.	v.	PROPN
dti-1313	194	13	1994	1994	NUM
dti-1313	194	14	(	(	PUNCT
dti-1313	194	15	b	b	NOUN
dti-1313	194	16	)	)	PUNCT
dti-1313	194	17	.	.	PUNCT
dti-1313	195	1	inhibition	inhibition	NOUN
dti-1313	195	2	of	of	ADP
dti-1313	195	3	lymphocyte	lymphocyte	ADJ
dti-1313	195	4	proliferation	proliferation	NOUN
dti-1313	195	5	by	by	ADP
dti-1313	195	6	the	the	DET
dti-1313	195	7	anti	anti	ADJ
dti-1313	195	8	-	-	ADJ
dti-1313	195	9	arthritc	arthritc	ADJ
dti-1313	195	10	drug	drug	NOUN
dti-1313	195	11	of	of	ADP
dti-1313	195	12	sinomenine	sinomenine	NOUN
dti-1313	195	13	.	.	PUNCT
dti-1313	196	1	int	int	NOUN
dti-1313	196	2	.	.	PUNCT
dti-1313	197	1	j.	j.	PROPN
dti-1313	197	2	immunopharmacol	immunopharmacol	PROPN
dti-1313	197	3	.	.	PROPN
dti-1313	197	4	,	,	PUNCT
dti-1313	197	5	16(8):685–91	16(8):685–91	NUM
dti-1313	197	6	.	.	PUNCT
dti-1313	198	1	liu	liu	PROPN
dti-1313	198	2	,	,	PUNCT
dti-1313	198	3	l.	l.	PROPN
dti-1313	198	4	,	,	PUNCT
dti-1313	198	5	buchner	buchner	PROPN
dti-1313	198	6	,	,	PUNCT
dti-1313	198	7	e.	e.	PROPN
dti-1313	198	8	,	,	PUNCT
dti-1313	198	9	beitze	beitze	PROPN
dti-1313	198	10	,	,	PUNCT
dti-1313	198	11	d.	d.	PROPN
dti-1313	198	12	et	et	PROPN
dti-1313	198	13	al	al	PROPN
dti-1313	198	14	.	.	PROPN
dti-1313	198	15	1996	1996	NUM
dti-1313	198	16	.	.	PUNCT
dti-1313	199	1	amelioration	amelioration	NOUN
dti-1313	199	2	of	of	ADP
dti-1313	199	3	rat	rat	NOUN
dti-1313	199	4	experimental	experimental	ADJ
dti-1313	199	5	arthritides	arthritide	NOUN
dti-1313	199	6	by	by	ADP
dti-1313	199	7	treatment	treatment	NOUN
dti-1313	199	8	with	with	ADP
dti-1313	199	9	the	the	DET
dti-1313	199	10	alkaloid	alkaloid	PROPN
dti-1313	199	11	sinomenine	sinomenine	NOUN
dti-1313	199	12	.	.	PUNCT
dti-1313	200	1	int	int	NOUN
dti-1313	200	2	.	.	PUNCT
dti-1313	201	1	j.	j.	PROPN
dti-1313	201	2	immunopharmacol	immunopharmacol	PROPN
dti-1313	201	3	.	.	PROPN
dti-1313	201	4	,	,	PUNCT
dti-1313	201	5	18(10):529–43	18(10):529–43	PROPN
dti-1313	202	1	.	.	PUNCT
dti-1313	202	2	liu	liu	PROPN
dti-1313	202	3	,	,	PUNCT
dti-1313	202	4	z.q	z.q	PROPN
dti-1313	202	5	.	.	PROPN
dti-1313	202	6	,	,	PUNCT
dti-1313	202	7	chan	chan	PROPN
dti-1313	202	8	,	,	PUNCT
dti-1313	202	9	k.	k.	PROPN
dti-1313	202	10	,	,	PUNCT
dti-1313	202	11	zhou	zhou	PROPN
dti-1313	202	12	,	,	PUNCT
dti-1313	202	13	h.	h.	PROPN
dti-1313	202	14	et	et	PROPN
dti-1313	202	15	al	al	PROPN
dti-1313	202	16	.	.	PROPN
dti-1313	202	17	2005	2005	NUM
dti-1313	202	18	.	.	PUNCT
dti-1313	203	1	the	the	DET
dti-1313	203	2	pharmacokinetics	pharmacokinetic	NOUN
dti-1313	203	3	and	and	CCONJ
dti-1313	203	4	tissues	tissue	NOUN
dti-1313	203	5	distribution	distribution	NOUN
dti-1313	203	6	of	of	ADP
dti-1313	203	7	sinomenine	sinomenine	NOUN
dti-1313	203	8	in	in	ADP
dti-1313	203	9	rats	rat	NOUN
dti-1313	203	10	and	and	CCONJ
dti-1313	203	11	its	its	PRON
dti-1313	203	12	protein	protein	NOUN
dti-1313	203	13	binding	bind	VERB
dti-1313	203	14	ability	ability	NOUN
dti-1313	203	15	in	in	ADP
dti-1313	203	16	vitro	vitro	X
dti-1313	203	17	.	.	PUNCT
dti-1313	204	1	life	life	PROPN
dti-1313	204	2	sci	sci	PROPN
dti-1313	204	3	.	.	PROPN
dti-1313	204	4	,	,	PUNCT
dti-1313	205	1	77(25):3197–209	77(25):3197–209	X
dti-1313	205	2	.	.	PUNCT
dti-1313	206	1	lopez	lopez	NOUN
dti-1313	206	2	-	-	PUNCT
dti-1313	206	3	jaramillo	jaramillo	PROPN
dti-1313	206	4	,	,	PUNCT
dti-1313	206	5	p.	p.	PROPN
dti-1313	206	6	,	,	PUNCT
dti-1313	206	7	gonzalez	gonzalez	PROPN
dti-1313	206	8	,	,	PUNCT
dti-1313	206	9	m.c	m.c	PROPN
dti-1313	206	10	.	.	PROPN
dti-1313	206	11	,	,	PUNCT
dti-1313	206	12	palmer	palmer	PROPN
dti-1313	206	13	,	,	PUNCT
dti-1313	206	14	r.m	r.m	PROPN
dti-1313	206	15	.	.	PROPN
dti-1313	206	16	et	et	PROPN
dti-1313	206	17	al	al	PROPN
dti-1313	206	18	.	.	PROPN
dti-1313	206	19	1990	1990	NUM
dti-1313	206	20	.	.	PUNCT
dti-1313	207	1	the	the	DET
dti-1313	207	2	crucial	crucial	ADJ
dti-1313	207	3	role	role	NOUN
dti-1313	207	4	of	of	ADP
dti-1313	207	5	physiological	physiological	ADJ
dti-1313	207	6	ca2	ca2	PROPN
dti-1313	207	7	+	+	PROPN
dti-1313	207	8	concentrations	concentration	NOUN
dti-1313	207	9	in	in	ADP
dti-1313	207	10	the	the	DET
dti-1313	207	11	production	production	NOUN
dti-1313	207	12	of	of	ADP
dti-1313	207	13	endothelial	endothelial	ADJ
dti-1313	207	14	nitric	nitric	ADJ
dti-1313	207	15	oxide	oxide	NOUN
dti-1313	207	16	and	and	CCONJ
dti-1313	207	17	the	the	DET
dti-1313	207	18	control	control	NOUN
dti-1313	207	19	of	of	ADP
dti-1313	207	20	vascular	vascular	ADJ
dti-1313	207	21	tone	tone	NOUN
dti-1313	207	22	.	.	PUNCT
dti-1313	208	1	br	br	PROPN
dti-1313	208	2	.	.	PUNCT
dti-1313	209	1	j.	j.	PROPN
dti-1313	209	2	pharmacol	pharmacol	PROPN
dti-1313	209	3	.	.	PROPN
dti-1313	209	4	,	,	PUNCT
dti-1313	209	5	101(2):489–93	101(2):489–93	NUM
dti-1313	209	6	.	.	PUNCT
dti-1313	210	1	mark	mark	PROPN
dti-1313	210	2	,	,	PUNCT
dti-1313	210	3	w.	w.	PROPN
dti-1313	210	4	,	,	PUNCT
dti-1313	210	5	schneeberger	schneeberger	NOUN
dti-1313	210	6	,	,	PUNCT
dti-1313	210	7	s.	s.	PROPN
dti-1313	210	8	,	,	PUNCT
dti-1313	210	9	seiler	seiler	PROPN
dti-1313	210	10	,	,	PUNCT
dti-1313	210	11	r.	r.	PROPN
dti-1313	210	12	et	et	PROPN
dti-1313	210	13	al	al	PROPN
dti-1313	210	14	.	.	PROPN
dti-1313	210	15	2003	2003	NUM
dti-1313	210	16	.	.	PUNCT
dti-1313	211	1	sinomenine	sinomenine	NOUN
dti-1313	211	2	blocks	block	NOUN
dti-1313	211	3	tissue	tissue	NOUN
dti-1313	211	4	remodeling	remodeling	NOUN
dti-1313	211	5	in	in	ADP
dti-1313	211	6	a	a	DET
dti-1313	211	7	rat	rat	NOUN
dti-1313	211	8	model	model	NOUN
dti-1313	211	9	of	of	ADP
dti-1313	211	10	chronic	chronic	ADJ
dti-1313	211	11	cardiac	cardiac	ADJ
dti-1313	211	12	allograft	allograft	NOUN
dti-1313	211	13	rejection	rejection	NOUN
dti-1313	211	14	.	.	PUNCT
dti-1313	212	1	transplantation	transplantation	NOUN
dti-1313	212	2	,	,	PUNCT
dti-1313	212	3	15:940–5	15:940–5	NUM
dti-1313	212	4	.	.	PUNCT
dti-1313	213	1	nishida	nishida	PROPN
dti-1313	213	2	,	,	PUNCT
dti-1313	213	3	s.	s.	PROPN
dti-1313	213	4	,	,	PUNCT
dti-1313	213	5	and	and	CCONJ
dti-1313	213	6	satoh	satoh	NOUN
dti-1313	213	7	,	,	PUNCT
dti-1313	213	8	h.	h.	PROPN
dti-1313	213	9	2003	2003	NUM
dti-1313	213	10	.	.	PUNCT
dti-1313	214	1	mechanisms	mechanism	NOUN
dti-1313	214	2	for	for	ADP
dti-1313	214	3	the	the	DET
dti-1313	214	4	vasodilations	vasodilation	NOUN
dti-1313	214	5	induced	induce	VERB
dti-1313	214	6	by	by	ADP
dti-1313	214	7	ginkgo	ginkgo	NOUN
dti-1313	214	8	biloba	biloba	NOUN
dti-1313	214	9	extract	extract	NOUN
dti-1313	214	10	and	and	CCONJ
dti-1313	214	11	its	its	PRON
dti-1313	214	12	main	main	ADJ
dti-1313	214	13	constituent	constituent	NOUN
dti-1313	214	14	,	,	PUNCT
dti-1313	214	15	bilobalide	bilobalide	ADV
dti-1313	214	16	,	,	PUNCT
dti-1313	214	17	in	in	ADP
dti-1313	214	18	rat	rat	NOUN
dti-1313	214	19	aorta	aorta	NOUN
dti-1313	214	20	.	.	PUNCT
dti-1313	215	1	life	life	PROPN
dti-1313	215	2	sci	sci	PROPN
dti-1313	215	3	.	.	PROPN
dti-1313	215	4	,	,	PUNCT
dti-1313	215	5	72:2659–67	72:2659–67	NUM
dti-1313	215	6	.	.	PUNCT
dti-1313	216	1	nishida	nishida	PROPN
dti-1313	216	2	,	,	PUNCT
dti-1313	216	3	s.	s.	PROPN
dti-1313	216	4	,	,	PUNCT
dti-1313	216	5	and	and	CCONJ
dti-1313	216	6	satoh	satoh	NOUN
dti-1313	216	7	,	,	PUNCT
dti-1313	216	8	h.	h.	PROPN
dti-1313	216	9	2004	2004	NUM
dti-1313	216	10	.	.	PUNCT
dti-1313	217	1	comparative	comparative	ADJ
dti-1313	217	2	vasodilating	vasodilate	VERB
dti-1313	217	3	actions	action	NOUN
dti-1313	217	4	among	among	ADP
dti-1313	217	5	terpenoids	terpenoid	NOUN
dti-1313	217	6	and	and	CCONJ
dti-1313	217	7	fl	fl	PROPN
dti-1313	217	8	avonoids	avonoid	NOUN
dti-1313	217	9	contained	contain	VERB
dti-1313	217	10	in	in	ADP
dti-1313	217	11	ginkgo	ginkgo	NOUN
dti-1313	217	12	biloba	biloba	NOUN
dti-1313	217	13	extract	extract	NOUN
dti-1313	217	14	.	.	PUNCT
dti-1313	218	1	clinica	clinica	PROPN
dti-1313	218	2	chimica	chimica	PROPN
dti-1313	218	3	acta	acta	PROPN
dti-1313	218	4	.	.	PROPN
dti-1313	218	5	,	,	PUNCT
dti-1313	218	6	339:129–33	339:129–33	NUM
dti-1313	218	7	.	.	PUNCT
dti-1313	219	1	nishida	nishida	PROPN
dti-1313	219	2	,	,	PUNCT
dti-1313	219	3	s.	s.	PROPN
dti-1313	219	4	,	,	PUNCT
dti-1313	219	5	and	and	CCONJ
dti-1313	219	6	satoh	satoh	NOUN
dti-1313	219	7	,	,	PUNCT
dti-1313	219	8	h.	h.	PROPN
dti-1313	219	9	2006	2006	NUM
dti-1313	219	10	.	.	PUNCT
dti-1313	220	1	in	in	ADP
dti-1313	220	2	vitro	vitro	X
dti-1313	220	3	pharmacological	pharmacological	ADJ
dti-1313	220	4	actions	action	NOUN
dti-1313	220	5	of	of	ADP
dti-1313	220	6	sinomenine	sinomenine	NOUN
dti-1313	220	7	on	on	ADP
dti-1313	220	8	the	the	DET
dti-1313	220	9	smooth	smooth	ADJ
dti-1313	220	10	muscle	muscle	NOUN
dti-1313	220	11	and	and	CCONJ
dti-1313	220	12	endothelial	endothelial	NOUN
dti-1313	220	13	cell	cell	NOUN
dti-1313	220	14	activity	activity	NOUN
dti-1313	220	15	in	in	ADP
dti-1313	220	16	rat	rat	NOUN
dti-1313	220	17	aorta	aorta	NOUN
dti-1313	220	18	.	.	PUNCT
dti-1313	221	1	life	life	PROPN
dti-1313	221	2	sci	sci	PROPN
dti-1313	221	3	.	.	PROPN
dti-1313	221	4	,	,	PUNCT
dti-1313	221	5	79:1203–06	79:1203–06	NUM
dti-1313	221	6	.	.	PUNCT
dti-1313	222	1	nishida	nishida	PROPN
dti-1313	222	2	,	,	PUNCT
dti-1313	222	3	s.	s.	PROPN
dti-1313	222	4	,	,	PUNCT
dti-1313	222	5	and	and	CCONJ
dti-1313	222	6	satoh	satoh	NOUN
dti-1313	222	7	,	,	PUNCT
dti-1313	222	8	h.	h.	PROPN
dti-1313	222	9	2007	2007	NUM
dti-1313	222	10	.	.	PUNCT
dti-1313	223	1	vascular	vascular	ADJ
dti-1313	223	2	pharmacology	pharmacology	NOUN
dti-1313	223	3	of	of	ADP
dti-1313	223	4	mokuboito	mokuboito	NOUN
dti-1313	223	5	(	(	PUNCT
dti-1313	223	6	mu	mu	NOUN
dti-1313	223	7	-	-	PUNCT
dti-1313	223	8	fang	fang	NOUN
dti-1313	223	9	-	-	PUNCT
dti-1313	223	10	yi	yi	NOUN
dti-1313	223	11	-	-	PUNCT
dti-1313	223	12	tang	tang	NOUN
dti-1313	223	13	)	)	PUNCT
dti-1313	223	14	and	and	CCONJ
dti-1313	223	15	its	its	PRON
dti-1313	223	16	constituents	constituent	NOUN
dti-1313	223	17	on	on	ADP
dti-1313	223	18	the	the	DET
dti-1313	223	19	smooth	smooth	ADJ
dti-1313	223	20	muscle	muscle	NOUN
dti-1313	223	21	and	and	CCONJ
dti-1313	223	22	the	the	DET
dti-1313	223	23	endothelium	endothelium	NOUN
dti-1313	223	24	in	in	ADP
dti-1313	223	25	rat	rat	NOUN
dti-1313	223	26	aorta	aorta	NOUN
dti-1313	223	27	.	.	PUNCT
dti-1313	224	1	ecam	ecam	NOUN
dti-1313	224	2	(	(	PUNCT
dti-1313	224	3	in	in	ADP
dti-1313	224	4	press	press	NOUN
dti-1313	224	5	)	)	PUNCT
dti-1313	224	6	.	.	PUNCT
dti-1313	225	1	quignard	quignard	PROPN
dti-1313	225	2	,	,	PUNCT
dti-1313	225	3	j.f	j.f	PROPN
dti-1313	225	4	.	.	PROPN
dti-1313	225	5	,	,	PUNCT
dti-1313	225	6	feleton	feleton	PROPN
dti-1313	225	7	,	,	PUNCT
dti-1313	225	8	m.	m.	NOUN
dti-1313	225	9	,	,	PUNCT
dti-1313	225	10	thollon	thollon	ADV
dti-1313	225	11	,	,	PUNCT
dti-1313	225	12	c.	c.	PROPN
dti-1313	225	13	et	et	PROPN
dti-1313	225	14	al	al	PROPN
dti-1313	225	15	.	.	PROPN
dti-1313	225	16	1999	1999	NUM
dti-1313	225	17	.	.	PUNCT
dti-1313	226	1	pottasium	pottasium	NOUN
dti-1313	226	2	ions	ion	NOUN
dti-1313	226	3	and	and	CCONJ
dti-1313	226	4	endothelium	endothelium	NOUN
dti-1313	226	5	-	-	PUNCT
dti-1313	226	6	derived	derive	VERB
dti-1313	226	7	hyperpolarizing	hyperpolarizing	NOUN
dti-1313	226	8	factor	factor	NOUN
dti-1313	226	9	in	in	ADP
dti-1313	226	10	guinea	guinea	NOUN
dti-1313	226	11	-	-	PUNCT
dti-1313	226	12	pig	pig	NOUN
dti-1313	226	13	carotid	carotid	NOUN
dti-1313	226	14	and	and	CCONJ
dti-1313	226	15	porcine	porcine	VERB
dti-1313	226	16	coronary	coronary	ADJ
dti-1313	226	17	arteries	artery	NOUN
dti-1313	226	18	.	.	PUNCT
dti-1313	227	1	br	br	X
dti-1313	227	2	.	.	PUNCT
dti-1313	228	1	j.	j.	PROPN
dti-1313	228	2	pharmacol	pharmacol	PROPN
dti-1313	228	3	.	.	PROPN
dti-1313	228	4	,	,	PUNCT
dti-1313	228	5	127:27–37	127:27–37	X
dti-1313	228	6	.	.	PUNCT
dti-1313	229	1	figure	figure	NOUN
dti-1313	229	2	6	6	NUM
dti-1313	229	3	.	.	PUNCT
dti-1313	230	1	shame	shame	NOUN
dti-1313	230	2	for	for	ADP
dti-1313	230	3	the	the	DET
dti-1313	230	4	changes	change	NOUN
dti-1313	230	5	in	in	ADP
dti-1313	230	6	cardiac	cardiac	ADJ
dti-1313	230	7	ionic	ionic	ADJ
dti-1313	230	8	channels	channel	NOUN
dti-1313	230	9	induced	induce	VERB
dti-1313	230	10	by	by	ADP
dti-1313	230	11	sinomenine	sinomenine	NOUN
dti-1313	230	12	.	.	PUNCT
dti-1313	231	1	superimposed	superimpose	VERB
dti-1313	231	2	action	action	NOUN
dti-1313	231	3	potentials	potential	NOUN
dti-1313	231	4	are	be	AUX
dti-1313	231	5	in	in	ADP
dti-1313	231	6	control	control	NOUN
dti-1313	231	7	(	(	PUNCT
dti-1313	231	8	solid	solid	ADJ
dti-1313	231	9	line	line	NOUN
dti-1313	231	10	)	)	PUNCT
dti-1313	231	11	and	and	CCONJ
dti-1313	231	12	in	in	ADP
dti-1313	231	13	sinomenine	sinomenine	NOUN
dti-1313	231	14	(	(	PUNCT
dti-1313	231	15	dash	dash	NOUN
dti-1313	231	16	line	line	NOUN
dti-1313	231	17	)	)	PUNCT
dti-1313	231	18	.	.	PUNCT
dti-1313	232	1	ina	ina	PROPN
dti-1313	232	2	:	:	PUNCT
dti-1313	232	3	the	the	DET
dti-1313	232	4	na+	na+	NOUN
dti-1313	232	5	channel	channel	PROPN
dti-1313	232	6	,	,	PUNCT
dti-1313	232	7	ica	ica	PROPN
dti-1313	232	8	:	:	PUNCT
dti-1313	232	9	the	the	DET
dti-1313	232	10	ca2	ca2	PROPN
dti-1313	232	11	+	+	PROPN
dti-1313	232	12	channel	channel	PROPN
dti-1313	232	13	,	,	PUNCT
dti-1313	232	14	ik	ik	PROPN
dti-1313	232	15	:	:	PUNCT
dti-1313	232	16	the	the	DET
dti-1313	232	17	delayed	delay	VERB
dti-1313	232	18	rectifi	rectifi	NOUN
dti-1313	232	19	er	er	INTJ
dti-1313	232	20	k+channel	k+channel	PROPN
dti-1313	232	21	,	,	PUNCT
dti-1313	232	22	ik1	ik1	ADV
dti-1313	232	23	:	:	PUNCT
dti-1313	232	24	the	the	DET
dti-1313	232	25	inwardly	inwardly	ADV
dti-1313	232	26	rectifying	rectifying	NOUN
dti-1313	232	27	k+channel	k+channel	PROPN
dti-1313	232	28	.	.	PUNCT
dti-1313	233	1	satoh	satoh	PROPN
dti-1313	233	2	et	et	PROPN
dti-1313	233	3	al.indd	al.indd	X
dti-1313	233	4	7	7	NUM
dti-1313	233	5	5/14/2007	5/14/2007	NUM
dti-1313	233	6	8:59:10	8:59:10	PROPN
dti-1313	233	7	pm	pm	NOUN
dti-1313	233	8	103	103	NUM
dti-1313	233	9	nishida	nishida	NOUN
dti-1313	233	10	and	and	CCONJ
dti-1313	233	11	satoh	satoh	NOUN
dti-1313	233	12	drug	drug	NOUN
dti-1313	233	13	target	target	NOUN
dti-1313	233	14	insights	insight	NOUN
dti-1313	233	15	2007	2007	NUM
dti-1313	233	16	:	:	SYM
dti-1313	233	17	2	2	NUM
dti-1313	233	18	satoh	satoh	NOUN
dti-1313	233	19	,	,	PUNCT
dti-1313	233	20	h.	h.	PROPN
dti-1313	233	21	1996	1996	NUM
dti-1313	233	22	.	.	PUNCT
dti-1313	234	1	modulation	modulation	NOUN
dti-1313	234	2	of	of	ADP
dti-1313	234	3	ca2	ca2	PROPN
dti-1313	234	4	+	+	PROPN
dti-1313	234	5	-activated	-activated	ADJ
dti-1313	234	6	k+	k+	NOUN
dti-1313	234	7	current	current	ADJ
dti-1313	234	8	by	by	ADP
dti-1313	234	9	isoprenaline	isoprenaline	NOUN
dti-1313	234	10	,	,	PUNCT
dti-1313	234	11	carbachol	carbachol	NOUN
dti-1313	234	12	,	,	PUNCT
dti-1313	234	13	and	and	CCONJ
dti-1313	234	14	phorbol	phorbol	NOUN
dti-1313	234	15	ester	ester	NOUN
dti-1313	234	16	in	in	ADP
dti-1313	234	17	cultured	cultured	ADJ
dti-1313	234	18	(	(	PUNCT
dti-1313	234	19	and	and	CCONJ
dti-1313	234	20	fresh	fresh	ADJ
dti-1313	234	21	)	)	PUNCT
dti-1313	234	22	rat	rat	NOUN
dti-1313	234	23	aortic	aortic	ADJ
dti-1313	234	24	vascular	vascular	ADJ
dti-1313	234	25	smooth	smooth	ADJ
dti-1313	234	26	muscle	muscle	NOUN
dti-1313	234	27	cells	cell	NOUN
dti-1313	234	28	.	.	PUNCT
dti-1313	235	1	gen	gen	PROPN
dti-1313	235	2	.	.	PROPN
dti-1313	235	3	pharmacol	pharmacol	PROPN
dti-1313	235	4	.	.	PROPN
dti-1313	235	5	,	,	PUNCT
dti-1313	235	6	27:319–24	27:319–24	PROPN
dti-1313	235	7	.	.	PUNCT
dti-1313	236	1	satoh	satoh	PROPN
dti-1313	236	2	,	,	PUNCT
dti-1313	236	3	h.	h.	PROPN
dti-1313	236	4	2001	2001	NUM
dti-1313	236	5	.	.	PUNCT
dti-1313	237	1	[	[	X
dti-1313	237	2	ca2+]idependent	ca2+]idependent	ADJ
dti-1313	237	3	actions	action	NOUN
dti-1313	237	4	of	of	ADP
dti-1313	237	5	taurine	taurine	NOUN
dti-1313	237	6	in	in	ADP
dti-1313	237	7	spontaneously	spontaneously	ADV
dti-1313	237	8	beating	beat	VERB
dti-1313	237	9	rabbit	rabbit	NOUN
dti-1313	237	10	sino	sino	ADJ
dti-1313	237	11	-	-	PUNCT
dti-1313	237	12	atrial	atrial	ADJ
dti-1313	237	13	nodal	nodal	NOUN
dti-1313	237	14	cells	cell	NOUN
dti-1313	237	15	.	.	PUNCT
dti-1313	238	1	eur	eur	PROPN
dti-1313	238	2	.	.	PUNCT
dti-1313	239	1	j.	j.	PROPN
dti-1313	239	2	pharmacol	pharmacol	PROPN
dti-1313	239	3	.	.	PROPN
dti-1313	239	4	,	,	PUNCT
dti-1313	239	5	424:19–25	424:19–25	X
dti-1313	239	6	.	.	PUNCT
dti-1313	239	7	satoh	satoh	NOUN
dti-1313	239	8	,	,	PUNCT
dti-1313	239	9	h.	h.	PROPN
dti-1313	239	10	2003	2003	NUM
dti-1313	239	11	.	.	PUNCT
dti-1313	240	1	effects	effect	NOUN
dti-1313	240	2	of	of	ADP
dti-1313	240	3	ginkgo	ginkgo	NOUN
dti-1313	240	4	biloba	biloba	NOUN
dti-1313	240	5	extract	extract	NOUN
dti-1313	240	6	and	and	CCONJ
dti-1313	240	7	bilobalide	bilobalide	ADV
dti-1313	240	8	,	,	PUNCT
dti-1313	240	9	a	a	DET
dti-1313	240	10	main	main	ADJ
dti-1313	240	11	constituent	constituent	NOUN
dti-1313	240	12	,	,	PUNCT
dti-1313	240	13	on	on	ADP
dti-1313	240	14	the	the	DET
dti-1313	240	15	ionic	ionic	ADJ
dti-1313	240	16	currents	current	NOUN
dti-1313	240	17	in	in	ADP
dti-1313	240	18	guinea	guinea	NOUN
dti-1313	240	19	pig	pig	NOUN
dti-1313	240	20	ventricular	ventricular	ADJ
dti-1313	240	21	cardiomyocytes	cardiomyocyte	NOUN
dti-1313	240	22	.	.	PUNCT
dti-1313	241	1	arzneimittelforschung	arzneimittelforschung	ADJ
dti-1313	241	2	,	,	PUNCT
dti-1313	241	3	53:407–13	53:407–13	NUM
dti-1313	241	4	.	.	PUNCT
dti-1313	241	5	satoh	satoh	NOUN
dti-1313	241	6	,	,	PUNCT
dti-1313	241	7	h.	h.	PROPN
dti-1313	241	8	2005	2005	NUM
dti-1313	241	9	.	.	PUNCT
dti-1313	242	1	electropharmacology	electropharmacology	NOUN
dti-1313	242	2	of	of	ADP
dti-1313	242	3	sinomeni	sinomeni	NOUN
dti-1313	242	4	caulis	cauli	NOUN
dti-1313	242	5	et	et	NOUN
dti-1313	242	6	rhizome	rhizome	NOUN
dti-1313	242	7	and	and	CCONJ
dti-1313	242	8	its	its	PRON
dti-1313	242	9	constituents	constituent	NOUN
dti-1313	242	10	in	in	ADP
dti-1313	242	11	cardiomyocytes	cardiomyocyte	NOUN
dti-1313	242	12	.	.	PUNCT
dti-1313	243	1	am	be	AUX
dti-1313	243	2	.	.	PUNCT
dti-1313	244	1	j.	j.	PROPN
dti-1313	244	2	chin	chin	PROPN
dti-1313	244	3	.	.	PUNCT
dti-1313	244	4	med	med	PROPN
dti-1313	244	5	.	.	PROPN
dti-1313	244	6	,	,	PUNCT
dti-1313	244	7	33:967–79	33:967–79	ADV
dti-1313	244	8	.	.	PUNCT
dti-1313	245	1	satoh	satoh	NOUN
dti-1313	245	2	,	,	PUNCT
dti-1313	245	3	h.	h.	PROPN
dti-1313	245	4	,	,	PUNCT
dti-1313	245	5	and	and	CCONJ
dti-1313	245	6	sperelakis	sperelakis	PROPN
dti-1313	245	7	,	,	PUNCT
dti-1313	245	8	n.	n.	PROPN
dti-1313	245	9	1991	1991	NUM
dti-1313	245	10	.	.	PUNCT
dti-1313	246	1	calcium	calcium	NOUN
dti-1313	246	2	and	and	CCONJ
dti-1313	246	3	potassium	potassium	NOUN
dti-1313	246	4	currents	current	NOUN
dti-1313	246	5	in	in	ADP
dti-1313	246	6	cultured	cultured	ADJ
dti-1313	246	7	rat	rat	NOUN
dti-1313	246	8	aortic	aortic	ADJ
dti-1313	246	9	vascular	vascular	ADJ
dti-1313	246	10	smooth	smooth	ADJ
dti-1313	246	11	muscle	muscle	NOUN
dti-1313	246	12	cell	cell	NOUN
dti-1313	246	13	lines	line	NOUN
dti-1313	246	14	.	.	PUNCT
dti-1313	247	1	in	in	ADP
dti-1313	247	2	sperelakis	sperelakis	PROPN
dti-1313	247	3	n	n	PROPN
dti-1313	247	4	ed	ed	NOUN
dti-1313	247	5	.	.	PUNCT
dti-1313	247	6	ion	ion	NOUN
dti-1313	247	7	channels	channel	NOUN
dti-1313	247	8	of	of	ADP
dti-1313	247	9	vascular	vascular	ADJ
dti-1313	247	10	smooth	smooth	ADJ
dti-1313	247	11	muscle	muscle	NOUN
dti-1313	247	12	cells	cell	NOUN
dti-1313	247	13	and	and	CCONJ
dti-1313	247	14	endothelial	endothelial	ADJ
dti-1313	247	15	cells	cell	NOUN
dti-1313	247	16	.	.	PUNCT
dti-1313	248	1	academic	academic	ADJ
dti-1313	248	2	press	press	NOUN
dti-1313	248	3	,	,	PUNCT
dti-1313	248	4	new	new	PROPN
dti-1313	248	5	york	york	PROPN
dti-1313	248	6	:	:	PUNCT
dti-1313	248	7	p55–63	p55–63	NOUN
dti-1313	248	8	.	.	PUNCT
dti-1313	248	9	satoh	satoh	PROPN
dti-1313	248	10	,	,	PUNCT
dti-1313	248	11	h.	h.	PROPN
dti-1313	248	12	and	and	CCONJ
dti-1313	248	13	sperelakis	sperelakis	PROPN
dti-1313	248	14	,	,	PUNCT
dti-1313	248	15	n.	n.	NOUN
dti-1313	248	16	1995	1995	NUM
dti-1313	248	17	.	.	PUNCT
dti-1313	249	1	modulation	modulation	NOUN
dti-1313	249	2	of	of	ADP
dti-1313	249	3	l	l	NOUN
dti-1313	249	4	-	-	PUNCT
dti-1313	249	5	type	type	NOUN
dti-1313	249	6	ca2	ca2	PROPN
dti-1313	249	7	+	+	NOUN
dti-1313	249	8	current	current	ADJ
dti-1313	249	9	by	by	ADP
dti-1313	249	10	isoprenaline	isoprenaline	NOUN
dti-1313	249	11	,	,	PUNCT
dti-1313	249	12	carbachol	carbachol	NOUN
dti-1313	249	13	and	and	CCONJ
dti-1313	249	14	phorbol	phorbol	NOUN
dti-1313	249	15	ester	ester	NOUN
dti-1313	249	16	in	in	ADP
dti-1313	249	17	cultured	cultured	ADJ
dti-1313	249	18	rat	rat	NOUN
dti-1313	249	19	aortic	aortic	ADJ
dti-1313	249	20	vascular	vascular	ADJ
dti-1313	249	21	smooth	smooth	ADJ
dti-1313	249	22	muscle	muscle	NOUN
dti-1313	249	23	(	(	PUNCT
dti-1313	249	24	a7r5	a7r5	NOUN
dti-1313	249	25	)	)	PUNCT
dti-1313	249	26	cells	cell	NOUN
dti-1313	249	27	.	.	PUNCT
dti-1313	250	1	gen	gen	PROPN
dti-1313	250	2	.	.	PROPN
dti-1313	250	3	pharmacol	pharmacol	PROPN
dti-1313	250	4	.	.	PROPN
dti-1313	250	5	,	,	PUNCT
dti-1313	250	6	26	26	NUM
dti-1313	250	7	:	:	PUNCT
dti-1313	250	8	369–79	369–79	NUM
dti-1313	250	9	.	.	PUNCT
dti-1313	251	1	satoh	satoh	NOUN
dti-1313	251	2	,	,	PUNCT
dti-1313	251	3	h.	h.	PROPN
dti-1313	251	4	and	and	CCONJ
dti-1313	251	5	sperelakis	sperelakis	PROPN
dti-1313	251	6	,	,	PUNCT
dti-1313	251	7	n.	n.	PROPN
dti-1313	251	8	1998	1998	NUM
dti-1313	251	9	.	.	PUNCT
dti-1313	252	1	review	review	NOUN
dti-1313	252	2	of	of	ADP
dti-1313	252	3	some	some	DET
dti-1313	252	4	actions	action	NOUN
dti-1313	252	5	of	of	ADP
dti-1313	252	6	taurine	taurine	NOUN
dti-1313	252	7	on	on	ADP
dti-1313	252	8	ion	ion	NOUN
dti-1313	252	9	channels	channel	NOUN
dti-1313	252	10	of	of	ADP
dti-1313	252	11	cardiac	cardiac	ADJ
dti-1313	252	12	muscle	muscle	NOUN
dti-1313	252	13	cells	cell	NOUN
dti-1313	252	14	and	and	CCONJ
dti-1313	252	15	others	other	NOUN
dti-1313	252	16	.	.	PUNCT
dti-1313	253	1	gen	gen	PROPN
dti-1313	253	2	.	.	PROPN
dti-1313	253	3	pharmacol	pharmacol	PROPN
dti-1313	253	4	.	.	PROPN
dti-1313	253	5	,	,	PUNCT
dti-1313	253	6	30:451–63	30:451–63	PROPN
dti-1313	253	7	.	.	PUNCT
dti-1313	254	1	shuji	shuji	PROPN
dti-1313	254	2	,	,	PUNCT
dti-1313	254	3	y.	y.	PROPN
dti-1313	254	4	,	,	PUNCT
dti-1313	254	5	kinoshita	kinoshita	PROPN
dti-1313	254	6	,	,	PUNCT
dti-1313	254	7	y.	y.	PROPN
dti-1313	254	8	,	,	PUNCT
dti-1313	254	9	arakawa	arakawa	PROPN
dti-1313	254	10	,	,	PUNCT
dti-1313	254	11	y.	y.	PROPN
dti-1313	254	12	et	et	PROPN
dti-1313	254	13	al	al	PROPN
dti-1313	254	14	.	.	PROPN
dti-1313	254	15	2002	2002	NUM
dti-1313	254	16	.	.	PUNCT
dti-1313	255	1	clinical	clinical	ADJ
dti-1313	255	2	evaluation	evaluation	NOUN
dti-1313	255	3	of	of	ADP
dti-1313	255	4	moku	moku	NOUN
dti-1313	255	5	-	-	PUNCT
dti-1313	255	6	boi	boi	NOUN
dti-1313	255	7	-	-	PUNCT
dti-1313	255	8	to(mu	to(mu	NOUN
dti-1313	255	9	-	-	PUNCT
dti-1313	255	10	fang	fang	NOUN
dti-1313	255	11	-	-	PUNCT
dti-1313	255	12	yi	yi	NOUN
dti-1313	255	13	-	-	PUNCT
dti-1313	255	14	tang	tang	NOUN
dti-1313	255	15	):	):	PUNCT
dti-1313	255	16	a	a	DET
dti-1313	255	17	japanese	japanese	ADJ
dti-1313	255	18	and	and	CCONJ
dti-1313	255	19	chinese	chinese	ADJ
dti-1313	255	20	traditional	traditional	ADJ
dti-1313	255	21	medicine	medicine	NOUN
dti-1313	255	22	for	for	ADP
dti-1313	255	23	heart	heart	NOUN
dti-1313	255	24	failure	failure	NOUN
dti-1313	255	25	.	.	PUNCT
dti-1313	256	1	j.	j.	PROPN
dti-1313	256	2	trad	trad	PROPN
dti-1313	256	3	.	.	PUNCT
dti-1313	257	1	med	med	PROPN
dti-1313	257	2	.	.	PROPN
dti-1313	257	3	,	,	PUNCT
dti-1313	257	4	19:159–63	19:159–63	NUM
dti-1313	257	5	.	.	PUNCT
dti-1313	258	1	wang	wang	PROPN
dti-1313	258	2	,	,	PUNCT
dti-1313	258	3	y.	y.	PROPN
dti-1313	258	4	,	,	PUNCT
dti-1313	258	5	fang	fang	PROPN
dti-1313	258	6	,	,	PUNCT
dti-1313	258	7	y.	y.	PROPN
dti-1313	258	8	,	,	PUNCT
dti-1313	258	9	huang	huang	PROPN
dti-1313	258	10	,	,	PUNCT
dti-1313	258	11	w.	w.	PROPN
dti-1313	258	12	et	et	PROPN
dti-1313	258	13	al	al	PROPN
dti-1313	258	14	.	.	PROPN
dti-1313	258	15	2005	2005	NUM
dti-1313	258	16	.	.	PUNCT
dti-1313	259	1	effect	effect	NOUN
dti-1313	259	2	of	of	ADP
dti-1313	259	3	sinomenine	sinomenine	NOUN
dti-1313	259	4	on	on	ADP
dti-1313	259	5	cytokine	cytokine	ADJ
dti-1313	259	6	expression	expression	NOUN
dti-1313	259	7	of	of	ADP
dti-1313	259	8	macrophages	macrophage	NOUN
dti-1313	259	9	and	and	CCONJ
dti-1313	259	10	synoviocytes	synoviocyte	NOUN
dti-1313	259	11	in	in	ADP
dti-1313	259	12	adjuvant	adjuvant	ADJ
dti-1313	259	13	arthritis	arthritis	NOUN
dti-1313	259	14	rats	rat	NOUN
dti-1313	259	15	.	.	PUNCT
dti-1313	260	1	j.	j.	PROPN
dti-1313	260	2	ethopharmacol	ethopharmacol	PROPN
dti-1313	260	3	.	.	PROPN
dti-1313	260	4	,	,	PUNCT
dti-1313	260	5	98:37–43	98:37–43	NUM
dti-1313	260	6	.	.	PUNCT
dti-1313	260	7	yamasaki	yamasaki	PROPN
dti-1313	260	8	,	,	PUNCT
dti-1313	260	9	h.	h.	PROPN
dti-1313	260	10	1976	1976	NUM
dti-1313	260	11	.	.	PUNCT
dti-1313	261	1	pharmacology	pharmacology	NOUN
dti-1313	261	2	of	of	ADP
dti-1313	261	3	sinomenine	sinomenine	NOUN
dti-1313	261	4	,	,	PUNCT
dti-1313	261	5	an	an	DET
dti-1313	261	6	anti	anti	ADJ
dti-1313	261	7	-	-	ADJ
dti-1313	261	8	rheumatic	rheumatic	ADJ
dti-1313	261	9	alkaloids	alkaloid	NOUN
dti-1313	261	10	from	from	ADP
dti-1313	261	11	sinomenine	sinomenine	PROPN
dti-1313	261	12	acutum	acutum	PROPN
dti-1313	261	13	.	.	PUNCT
dti-1313	262	1	acta	acta	PROPN
dti-1313	262	2	med	med	PROPN
dti-1313	262	3	okayama	okayama	PROPN
dti-1313	262	4	,	,	PUNCT
dti-1313	262	5	30:1–20	30:1–20	NUM
dti-1313	262	6	.	.	PUNCT
dti-1313	263	1	xie	xie	PROPN
dti-1313	263	2	,	,	PUNCT
dti-1313	263	3	s.x	s.x	PROPN
dti-1313	263	4	.	.	PROPN
dti-1313	263	5	,	,	PUNCT
dti-1313	263	6	and	and	CCONJ
dti-1313	263	7	jin	jin	NOUN
dti-1313	263	8	,	,	PUNCT
dti-1313	263	9	q.q	q.q	PROPN
dti-1313	263	10	.	.	PROPN
dti-1313	263	11	1993	1993	NUM
dti-1313	263	12	.	.	PUNCT
dti-1313	264	1	prevention	prevention	NOUN
dti-1313	264	2	of	of	ADP
dti-1313	264	3	sinomenine	sinomenine	NOUN
dti-1313	264	4	on	on	ADP
dti-1313	264	5	isolated	isolated	ADJ
dti-1313	264	6	rat	rat	NOUN
dti-1313	264	7	myocardial	myocardial	ADJ
dti-1313	264	8	reperfusion	reperfusion	NOUN
dti-1313	264	9	injury	injury	NOUN
dti-1313	264	10	.	.	PUNCT
dti-1313	265	1	zhongguo	zhongguo	PROPN
dti-1313	265	2	yao	yao	PROPN
dti-1313	265	3	li	li	PROPN
dti-1313	265	4	xue	xue	PROPN
dti-1313	265	5	bao	bao	PROPN
dti-1313	265	6	,	,	PUNCT
dti-1313	265	7	suppl	suppl	PROPN
dti-1313	265	8	:	:	PUNCT
dti-1313	265	9	s12–5	s12–5	PROPN
dti-1313	265	10	.	.	PUNCT
dti-1313	265	11	yan	yan	PROPN
dti-1313	265	12	,	,	PUNCT
dti-1313	265	13	x.h	x.h	PROPN
dti-1313	265	14	.	.	PROPN
dti-1313	265	15	,	,	PUNCT
dti-1313	265	16	li	li	PROPN
dti-1313	265	17	,	,	PUNCT
dti-1313	265	18	h.d	h.d	PROPN
dti-1313	265	19	.	.	PROPN
dti-1313	265	20	,	,	PUNCT
dti-1313	265	21	peng	peng	PROPN
dti-1313	265	22	,	,	PUNCT
dti-1313	265	23	w.x	w.x	PROPN
dti-1313	265	24	.	.	PROPN
dti-1313	265	25	et	et	PROPN
dti-1313	265	26	al	al	PROPN
dti-1313	265	27	.	.	PROPN
dti-1313	265	28	1997	1997	NUM
dti-1313	265	29	.	.	PUNCT
dti-1313	266	1	determination	determination	NOUN
dti-1313	266	2	of	of	ADP
dti-1313	266	3	sinomenine	sinomenine	NOUN
dti-1313	266	4	hcl	hcl	PROPN
dti-1313	266	5	in	in	ADP
dti-1313	266	6	serum	serum	NOUN
dti-1313	266	7	and	and	CCONJ
dti-1313	266	8	urine	urine	NOUN
dti-1313	266	9	by	by	ADP
dti-1313	266	10	hplc	hplc	NOUN
dti-1313	266	11	and	and	CCONJ
dti-1313	266	12	its	its	PRON
dti-1313	266	13	pharmacokinetics	pharmacokinetic	NOUN
dti-1313	266	14	in	in	ADP
dti-1313	266	15	normal	normal	ADJ
dti-1313	266	16	volunteers	volunteer	NOUN
dti-1313	266	17	.	.	PUNCT
dti-1313	267	1	yao	yao	PROPN
dti-1313	267	2	xue	xue	PROPN
dti-1313	267	3	xue	xue	PROPN
dti-1313	267	4	bao	bao	PROPN
dti-1313	267	5	,	,	PUNCT
dti-1313	267	6	32(8):620–4	32(8):620–4	NUM
dti-1313	267	7	.	.	PUNCT
dti-1313	268	1	zhao	zhao	PROPN
dti-1313	268	2	,	,	PUNCT
dti-1313	268	3	z.z	z.z	PROPN
dti-1313	268	4	.	.	PROPN
dti-1313	268	5	,	,	PUNCT
dti-1313	268	6	liang	liang	PROPN
dti-1313	268	7	,	,	PUNCT
dti-1313	268	8	z.t	z.t	PROPN
dti-1313	268	9	.	.	PROPN
dti-1313	268	10	,	,	PUNCT
dti-1313	268	11	zhou	zhou	PROPN
dti-1313	268	12	,	,	PUNCT
dti-1313	268	13	h.	h.	PROPN
dti-1313	268	14	et	et	PROPN
dti-1313	268	15	al	al	PROPN
dti-1313	268	16	.	.	PROPN
dti-1313	268	17	2005	2005	NUM
dti-1313	268	18	.	.	PUNCT
dti-1313	269	1	quantifi	quantifi	ADJ
dti-1313	269	2	cation	cation	NOUN
dti-1313	269	3	of	of	ADP
dti-1313	269	4	sinomenine	sinomenine	NOUN
dti-1313	269	5	in	in	ADP
dti-1313	269	6	caulis	caulis	ADJ
dti-1313	269	7	sinomenii	sinomenii	NOUN
dti-1313	269	8	collected	collect	VERB
dti-1313	269	9	from	from	ADP
dti-1313	269	10	different	different	ADJ
dti-1313	269	11	growing	grow	VERB
dti-1313	269	12	regions	region	NOUN
dti-1313	269	13	and	and	CCONJ
dti-1313	269	14	wholesale	wholesale	ADJ
dti-1313	269	15	herbal	herbal	ADJ
dti-1313	269	16	markets	market	NOUN
dti-1313	269	17	by	by	ADP
dti-1313	269	18	a	a	DET
dti-1313	269	19	modifi	modifi	NOUN
dti-1313	269	20	ed	ed	PROPN
dti-1313	269	21	hplc	hplc	NOUN
dti-1313	269	22	method	method	NOUN
dti-1313	269	23	.	.	PUNCT
dti-1313	270	1	biol	biol	PROPN
dti-1313	270	2	.	.	PUNCT
dti-1313	271	1	pharm	pharm	PROPN
dti-1313	271	2	.	.	PUNCT
dti-1313	272	1	bull	bull	PROPN
dti-1313	272	2	.	.	PUNCT
dti-1313	272	3	,	,	PUNCT
dti-1313	273	1	28(1):105–9	28(1):105–9	X
dti-1313	273	2	.	.	PUNCT
dti-1313	274	1	satoh	satoh	NOUN
dti-1313	274	2	et	et	NOUN
dti-1313	274	3	al.indd	al.indd	X
dti-1313	274	4	8	8	NUM
dti-1313	274	5	5/14/2007	5/14/2007	NUM
dti-1313	274	6	8:59:11	8:59:11	NUM
dti-1313	274	7	pm	pm	NOUN
dti-1313	274	8	104	104	NUM
dti-1313	274	9	<	<	X
dti-1313	274	10	<	<	X
dti-1313	274	11	/ascii85encodepages	/ascii85encodepage	NOUN
dti-1313	274	12	false	false	ADJ
dti-1313	274	13	/allowtransparency	/allowtransparency	NOUN
dti-1313	274	14	false	false	ADJ
dti-1313	274	15	/autopositionepsfiles	/autopositionepsfile	NOUN
dti-1313	274	16	true	true	ADJ
dti-1313	274	17	/autorotatepages	/autorotatepage	NOUN
dti-1313	274	18	/none	/none	PUNCT
dti-1313	274	19	/binding	/binding	PUNCT
dti-1313	275	1	/left	/left	ADJ
dti-1313	276	1	/calgrayprofile	/calgrayprofile	VERB
dti-1313	276	2	(	(	PUNCT
dti-1313	276	3	dot	dot	NOUN
dti-1313	276	4	gain	gain	NOUN
dti-1313	276	5	20	20	NUM
dti-1313	276	6	%	%	NOUN
dti-1313	276	7	)	)	PUNCT
dti-1313	276	8	/calrgbprofile	/calrgbprofile	PUNCT
dti-1313	277	1	(	(	PUNCT
dti-1313	277	2	srgb	srgb	PROPN
dti-1313	277	3	iec61966	iec61966	NOUN
dti-1313	277	4	-	-	PUNCT
dti-1313	277	5	2.1	2.1	NUM
dti-1313	277	6	)	)	PUNCT
dti-1313	277	7	/calcmykprofile	/calcmykprofile	PUNCT
dti-1313	278	1	(	(	PUNCT
dti-1313	278	2	u.s	u.s	PROPN
dti-1313	278	3	.	.	PROPN
dti-1313	278	4	web	web	NOUN
dti-1313	278	5	coated	coat	VERB
dti-1313	278	6	\050swop\051	\050swop\051	ADJ
dti-1313	278	7	v2	v2	NOUN
dti-1313	278	8	)	)	PUNCT
dti-1313	278	9	/srgbprofile	/srgbprofile	PUNCT
dti-1313	278	10	(	(	PUNCT
dti-1313	278	11	srgb	srgb	PROPN
dti-1313	278	12	iec61966	iec61966	NOUN
dti-1313	278	13	-	-	PUNCT
dti-1313	278	14	2.1	2.1	NUM
dti-1313	278	15	)	)	PUNCT
dti-1313	278	16	/cannotembedfontpolicy	/cannotembedfontpolicy	PUNCT
dti-1313	279	1	/error	/error	INTJ
dti-1313	279	2	/compatibilitylevel	/compatibilitylevel	NOUN
dti-1313	280	1	1.4	1.4	NUM
dti-1313	280	2	/compressobjects	/compressobject	NOUN
dti-1313	280	3	/tags	/tag	VERB
dti-1313	280	4	/compresspages	/compresspage	NOUN
dti-1313	280	5	true	true	ADJ
dti-1313	280	6	/convertimagestoindexed	/convertimagestoindexed	ADJ
dti-1313	280	7	true	true	ADJ
dti-1313	280	8	/passthroughjpegimages	/passthroughjpegimage	NOUN
dti-1313	280	9	true	true	ADJ
dti-1313	280	10	/createjdffile	/createjdffile	ADJ
dti-1313	280	11	false	false	ADJ
dti-1313	280	12	/createjobticket	/createjobticket	NOUN
dti-1313	280	13	false	false	ADJ
dti-1313	280	14	/defaultrenderingintent	/defaultrenderingintent	NOUN
dti-1313	280	15	/default	/default	PUNCT
dti-1313	280	16	/detectblends	/detectblend	NOUN
dti-1313	280	17	true	true	ADJ
dti-1313	280	18	/colorconversionstrategy	/colorconversionstrategy	NOUN
dti-1313	280	19	/leavecolorunchanged	/leavecolorunchange	VERB
dti-1313	280	20	/dothumbnails	/dothumbnail	VERB
dti-1313	280	21	false	false	ADJ
dti-1313	280	22	/embedallfonts	/embedallfont	NOUN
dti-1313	280	23	true	true	ADJ
dti-1313	280	24	/embedjoboptions	/embedjoboption	NOUN
dti-1313	280	25	true	true	ADJ
dti-1313	280	26	/dscreportinglevel	/dscreportinglevel	NOUN
dti-1313	280	27	0	0	NUM
dti-1313	280	28	/emitdscwarnings	/emitdscwarning	NOUN
dti-1313	280	29	false	false	ADJ
dti-1313	280	30	/endpage	/endpage	NOUN
dti-1313	280	31	-1	-1	NOUN
dti-1313	280	32	/imagememory	/imagememory	NUM
dti-1313	281	1	1048576	1048576	NUM
dti-1313	281	2	/lockdistillerparams	/lockdistillerparams	NOUN
dti-1313	281	3	false	false	ADJ
dti-1313	281	4	/maxsubsetpct	/maxsubsetpct	ADJ
dti-1313	281	5	100	100	NUM
dti-1313	281	6	/optimize	/optimize	NOUN
dti-1313	281	7	true	true	ADJ
dti-1313	281	8	/opm	/opm	NOUN
dti-1313	281	9	1	1	NUM
dti-1313	281	10	/parsedsccomments	/parsedsccomment	NOUN
dti-1313	281	11	true	true	ADJ
dti-1313	281	12	/parsedsccommentsfordocinfo	/parsedsccommentsfordocinfo	VERB
dti-1313	281	13	true	true	ADJ
dti-1313	281	14	/preservecopypage	/preservecopypage	NOUN
dti-1313	281	15	true	true	ADJ
dti-1313	281	16	/preserveepsinfo	/preserveepsinfo	NOUN
dti-1313	281	17	true	true	ADJ
dti-1313	281	18	/preservehalftoneinfo	/preservehalftoneinfo	PUNCT
dti-1313	281	19	false	false	ADJ
dti-1313	281	20	/preserveopicomments	/preserveopicomment	NOUN
dti-1313	281	21	false	false	ADJ
dti-1313	281	22	/preserveoverprintsettings	/preserveoverprintsetting	NOUN
dti-1313	281	23	true	true	ADJ
dti-1313	281	24	/startpage	/startpage	NOUN
dti-1313	281	25	1	1	NUM
dti-1313	281	26	/subsetfonts	/subsetfont	NOUN
dti-1313	281	27	true	true	ADJ
dti-1313	281	28	/transferfunctioninfo	/transferfunctioninfo	PUNCT
dti-1313	281	29	/apply	/apply	PUNCT
dti-1313	281	30	/ucrandbginfo	/ucrandbginfo	PUNCT
dti-1313	282	1	/preserve	/preserve	NOUN
dti-1313	282	2	/useprologue	/useprologue	NOUN
dti-1313	282	3	false	false	ADJ
dti-1313	282	4	/colorsettingsfile	/colorsettingsfile	NOUN
dti-1313	282	5	(	(	PUNCT
dti-1313	282	6	)	)	PUNCT
dti-1313	282	7	/alwaysembed	/alwaysembe	VERB
dti-1313	282	8	[	[	PUNCT
dti-1313	282	9	true	true	ADJ
dti-1313	282	10	]	]	PUNCT
dti-1313	282	11	/neverembed	/neverembed	PUNCT
dti-1313	283	1	[	[	PUNCT
dti-1313	283	2	true	true	ADJ
dti-1313	283	3	]	]	PUNCT
dti-1313	283	4	/antialiascolorimages	/antialiascolorimages	X
dti-1313	283	5	false	false	ADJ
dti-1313	283	6	/downsamplecolorimages	/downsamplecolorimage	NOUN
dti-1313	283	7	true	true	ADJ
dti-1313	283	8	/colorimagedownsampletype	/colorimagedownsampletype	PUNCT
dti-1313	283	9	/bicubic	/bicubic	NOUN
dti-1313	283	10	/colorimageresolution	/colorimageresolution	NOUN
dti-1313	283	11	300	300	NUM
dti-1313	283	12	/colorimagedepth	/colorimagedepth	PRON
dti-1313	284	1	-1	-1	INTJ
dti-1313	284	2	/colorimagedownsamplethreshold	/colorimagedownsamplethreshold	PUNCT
dti-1313	284	3	1.50000	1.50000	NUM
dti-1313	284	4	/encodecolorimages	/encodecolorimage	NOUN
dti-1313	284	5	true	true	ADJ
dti-1313	284	6	/colorimagefilter	/colorimagefilter	PUNCT
dti-1313	284	7	/dctencode	/dctencode	PUNCT
dti-1313	284	8	/autofiltercolorimages	/autofiltercolorimage	NOUN
dti-1313	284	9	true	true	ADJ
dti-1313	284	10	/colorimageautofilterstrategy	/colorimageautofilterstrategy	PUNCT
dti-1313	284	11	/jpeg	/jpeg	PUNCT
dti-1313	284	12	/coloracsimagedict	/coloracsimagedict	PUNCT
dti-1313	285	1	<	<	X
dti-1313	285	2	<	<	X
dti-1313	285	3	/qfactor	/qfactor	NOUN
dti-1313	285	4	0.15	0.15	NUM
dti-1313	285	5	/hsamples	/hsample	NOUN
dti-1313	286	1	[	[	X
dti-1313	286	2	1	1	NUM
dti-1313	286	3	1	1	NUM
dti-1313	286	4	1	1	NUM
dti-1313	286	5	1	1	NUM
dti-1313	286	6	]	]	PUNCT
dti-1313	286	7	/vsamples	/vsample	NOUN
dti-1313	287	1	[	[	X
dti-1313	287	2	1	1	NUM
dti-1313	287	3	1	1	NUM
dti-1313	287	4	1	1	NUM
dti-1313	287	5	1	1	NUM
dti-1313	287	6	]	]	PUNCT
dti-1313	287	7	>	>	PUNCT
dti-1313	287	8	>	>	X
dti-1313	287	9	/colorimagedict	/colorimagedict	PUNCT
dti-1313	288	1	<	<	X
dti-1313	288	2	<	<	X
dti-1313	288	3	/qfactor	/qfactor	NOUN
dti-1313	288	4	0.15	0.15	NUM
dti-1313	288	5	/hsamples	/hsample	NOUN
dti-1313	289	1	[	[	X
dti-1313	289	2	1	1	NUM
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dti-1313	316	3	>	>	X
dti-1313	316	4	/nld	/nld	PUNCT
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dti-1313	317	3	>	>	X
dti-1313	317	4	/esp	/esp	PUNCT
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dti-1313	318	3	>	>	X
dti-1313	318	4	/suo	/suo	PUNCT
dti-1313	319	1	<	<	X
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dti-1313	319	3	>	>	X
dti-1313	319	4	/ita	/ita	PUNCT
dti-1313	320	1	<	<	X
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dti-1313	320	3	>	>	X
dti-1313	320	4	/nor	/nor	X
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dti-1313	320	7	>	>	X
dti-1313	320	8	/sve	/sve	NOUN
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dti-1313	321	3	>	>	X
dti-1313	321	4	>	>	X
dti-1313	321	5	>	>	X
dti-1313	321	6	>	>	X
dti-1313	321	7	>	>	X
dti-1313	321	8	setdistillerparams	setdistillerparam	NOUN
dti-1313	322	1	<	<	X
dti-1313	322	2	<	<	X
dti-1313	322	3	/hwresolution	/hwresolution	NOUN
dti-1313	323	1	[	[	X
dti-1313	323	2	2400	2400	NUM
dti-1313	323	3	2400	2400	NUM
dti-1313	323	4	]	]	PUNCT
dti-1313	323	5	/pagesize	/pagesize	X
dti-1313	324	1	[	[	X
dti-1313	324	2	612.000	612.000	NUM
dti-1313	324	3	792.000	792.000	NUM
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dti-1313	324	5	>	>	PUNCT
dti-1313	324	6	>	>	X
dti-1313	324	7	setpagedevice	setpagedevice	PROPN