id	sid	tid	token	lemma	pos
dti-1329	1	1	tsen	tsen	PROPN
dti-1329	1	2	et	et	PROPN
dti-1329	1	3	al.indd	al.indd	X
dti-1329	1	4	drug	drug	NOUN
dti-1329	1	5	target	target	NOUN
dti-1329	1	6	insights	insight	NOUN
dti-1329	1	7	2008:3	2008:3	NUM
dti-1329	1	8	31–36	31–36	NUM
dti-1329	1	9	31	31	NUM
dti-1329	1	10	rapid	rapid	ADJ
dti-1329	1	11	communication	communication	NOUN
dti-1329	1	12	correspondence	correspondence	NOUN
dti-1329	1	13	:	:	PUNCT
dti-1329	1	14	shaw	shaw	PROPN
dti-1329	1	15	-	-	PUNCT
dti-1329	1	16	wei	wei	PROPN
dti-1329	1	17	d.	d.	PROPN
dti-1329	1	18	tsen	tsen	PROPN
dti-1329	1	19	,	,	PUNCT
dti-1329	1	20	department	department	NOUN
dti-1329	1	21	of	of	ADP
dti-1329	1	22	pathology	pathology	PROPN
dti-1329	1	23	,	,	PUNCT
dti-1329	1	24	johns	johns	PROPN
dti-1329	1	25	hopkins	hopkins	PROPN
dti-1329	1	26	medical	medical	ADJ
dti-1329	1	27	institutions	institution	NOUN
dti-1329	1	28	,	,	PUNCT
dti-1329	1	29	baltimore	baltimore	PROPN
dti-1329	1	30	,	,	PUNCT
dti-1329	1	31	md	md	PROPN
dti-1329	1	32	,	,	PUNCT
dti-1329	1	33	u.s.a	u.s.a	PROPN
dti-1329	1	34	.	.	PROPN
dti-1329	1	35	,	,	PUNCT
dti-1329	1	36	email	email	NOUN
dti-1329	1	37	:	:	PUNCT
dti-1329	2	1	tsen@jhu.edu	tsen@jhu.edu	PROPN
dti-1329	2	2	.	.	PUNCT
dti-1329	3	1	copyright	copyright	NOUN
dti-1329	3	2	in	in	ADP
dti-1329	3	3	this	this	DET
dti-1329	3	4	article	article	NOUN
dti-1329	3	5	,	,	PUNCT
dti-1329	3	6	its	its	PRON
dti-1329	3	7	metadata	metadata	NOUN
dti-1329	3	8	,	,	PUNCT
dti-1329	3	9	and	and	CCONJ
dti-1329	3	10	any	any	DET
dti-1329	3	11	supplementary	supplementary	ADJ
dti-1329	3	12	data	datum	NOUN
dti-1329	3	13	is	be	AUX
dti-1329	3	14	held	hold	VERB
dti-1329	3	15	by	by	ADP
dti-1329	3	16	its	its	PRON
dti-1329	3	17	author	author	NOUN
dti-1329	3	18	or	or	CCONJ
dti-1329	3	19	authors	author	NOUN
dti-1329	3	20	.	.	PUNCT
dti-1329	4	1	it	it	PRON
dti-1329	4	2	is	be	AUX
dti-1329	4	3	published	publish	VERB
dti-1329	4	4	under	under	ADP
dti-1329	4	5	the	the	DET
dti-1329	4	6	creative	creative	ADJ
dti-1329	4	7	commons	common	NOUN
dti-1329	4	8	attribution	attribution	NOUN
dti-1329	4	9	by	by	ADP
dti-1329	4	10	licence	licence	NOUN
dti-1329	4	11	.	.	PUNCT
dti-1329	5	1	for	for	SCONJ
dti-1329	5	2	further	further	ADJ
dti-1329	5	3	information	information	NOUN
dti-1329	5	4	go	go	VERB
dti-1329	5	5	to	to	ADP
dti-1329	5	6	:	:	PUNCT
dti-1329	5	7	http://creativecommons.org/licenses/by/3.0/.	http://creativecommons.org/licenses/by/3.0/.	VERB
dti-1329	5	8	evidence	evidence	NOUN
dti-1329	5	9	of	of	ADP
dti-1329	5	10	a	a	DET
dti-1329	5	11	novel	novel	ADJ
dti-1329	5	12	gene	gene	NOUN
dti-1329	5	13	from	from	ADP
dti-1329	5	14	aeromonas	aeromonas	PROPN
dti-1329	5	15	hydrophila	hydrophila	PROPN
dti-1329	5	16	encoding	encode	VERB
dti-1329	5	17	a	a	DET
dti-1329	5	18	putative	putative	ADJ
dti-1329	5	19	siderophore	siderophore	NOUN
dti-1329	5	20	receptor	receptor	NOUN
dti-1329	5	21	involved	involve	VERB
dti-1329	5	22	in	in	ADP
dti-1329	5	23	bacterial	bacterial	ADJ
dti-1329	5	24	growth	growth	NOUN
dti-1329	5	25	and	and	CCONJ
dti-1329	5	26	survival	survival	PROPN
dti-1329	5	27	shaw	shaw	PROPN
dti-1329	5	28	-	-	PUNCT
dti-1329	5	29	wei	wei	PROPN
dti-1329	5	30	d.	d.	PROPN
dti-1329	5	31	tsen	tsen	PROPN
dti-1329	5	32	department	department	PROPN
dti-1329	5	33	of	of	ADP
dti-1329	5	34	pathology	pathology	PROPN
dti-1329	5	35	,	,	PUNCT
dti-1329	5	36	johns	johns	PROPN
dti-1329	5	37	hopkins	hopkins	PROPN
dti-1329	5	38	medical	medical	ADJ
dti-1329	5	39	institutions	institution	NOUN
dti-1329	5	40	,	,	PUNCT
dti-1329	5	41	baltimore	baltimore	PROPN
dti-1329	5	42	,	,	PUNCT
dti-1329	5	43	md	md	PROPN
dti-1329	5	44	u.s.a	u.s.a	PROPN
dti-1329	5	45	.	.	PUNCT
dti-1329	6	1	abstract	abstract	PROPN
dti-1329	6	2	:	:	PUNCT
dti-1329	6	3	the	the	DET
dti-1329	6	4	pathogenic	pathogenic	ADJ
dti-1329	6	5	bacterium	bacterium	NOUN
dti-1329	6	6	aeromonas	aeromonas	PROPN
dti-1329	6	7	hydrophila	hydrophila	PROPN
dti-1329	6	8	has	have	AUX
dti-1329	6	9	been	be	AUX
dti-1329	6	10	shown	show	VERB
dti-1329	6	11	to	to	PART
dti-1329	6	12	exclusively	exclusively	ADV
dti-1329	6	13	utilize	utilize	VERB
dti-1329	6	14	a	a	DET
dti-1329	6	15	ligand	ligand	ADJ
dti-1329	6	16	exchange	exchange	NOUN
dti-1329	6	17	mechanism	mechanism	NOUN
dti-1329	6	18	for	for	ADP
dti-1329	6	19	siderophore	siderophore	ADV
dti-1329	6	20	-	-	PUNCT
dti-1329	6	21	mediated	mediate	VERB
dti-1329	6	22	iron	iron	NOUN
dti-1329	6	23	uptake	uptake	NOUN
dti-1329	6	24	,	,	PUNCT
dti-1329	6	25	with	with	ADP
dti-1329	6	26	a	a	DET
dti-1329	6	27	single	single	ADJ
dti-1329	6	28	nonspecifi	nonspecifi	NOUN
dti-1329	6	29	c	c	NOUN
dti-1329	6	30	siderophore	siderophore	ADV
dti-1329	6	31	receptor	receptor	NOUN
dti-1329	6	32	facilitating	facilitate	VERB
dti-1329	6	33	iron	iron	NOUN
dti-1329	6	34	exchange	exchange	NOUN
dti-1329	6	35	.	.	PUNCT
dti-1329	7	1	however	however	ADV
dti-1329	7	2	,	,	PUNCT
dti-1329	7	3	the	the	DET
dti-1329	7	4	genes	gene	NOUN
dti-1329	7	5	involved	involve	VERB
dti-1329	7	6	in	in	ADP
dti-1329	7	7	this	this	DET
dti-1329	7	8	process	process	NOUN
dti-1329	7	9	,	,	PUNCT
dti-1329	7	10	including	include	VERB
dti-1329	7	11	the	the	DET
dti-1329	7	12	gene	gene	NOUN
dti-1329	7	13	encoding	encode	VERB
dti-1329	7	14	the	the	DET
dti-1329	7	15	nonspecifi	nonspecifi	NOUN
dti-1329	7	16	c	c	PROPN
dti-1329	7	17	receptor	receptor	NOUN
dti-1329	7	18	,	,	PUNCT
dti-1329	7	19	are	be	AUX
dti-1329	7	20	unknown	unknown	ADJ
dti-1329	7	21	.	.	PUNCT
dti-1329	8	1	here	here	ADV
dti-1329	8	2	we	we	PRON
dti-1329	8	3	identify	identify	VERB
dti-1329	8	4	and	and	CCONJ
dti-1329	8	5	characterize	characterize	VERB
dti-1329	8	6	a	a	DET
dti-1329	8	7	novel	novel	ADJ
dti-1329	8	8	gene	gene	NOUN
dti-1329	8	9	,	,	PUNCT
dti-1329	8	10	nsr1	nsr1	PROPN
dti-1329	8	11	,	,	PUNCT
dti-1329	8	12	from	from	ADP
dti-1329	8	13	a.	a.	NOUN
dti-1329	8	14	hydrophila	hydrophila	NOUN
dti-1329	8	15	that	that	PRON
dti-1329	8	16	encodes	encode	VERB
dti-1329	8	17	a	a	DET
dti-1329	8	18	putative	putative	ADJ
dti-1329	8	19	protein	protein	NOUN
dti-1329	8	20	with	with	ADP
dti-1329	8	21	high	high	ADJ
dti-1329	8	22	homology	homology	NOUN
dti-1329	8	23	and	and	CCONJ
dti-1329	8	24	signifi	signifi	NOUN
dti-1329	8	25	ca	can	AUX
dti-1329	8	26	nt	not	PART
dti-1329	8	27	predicted	predict	VERB
dti-1329	8	28	structural	structural	ADJ
dti-1329	8	29	similarities	similarity	NOUN
dti-1329	8	30	to	to	ADP
dti-1329	8	31	the	the	DET
dti-1329	8	32	fhua	fhua	NOUN
dti-1329	8	33	protein	protein	NOUN
dti-1329	8	34	and	and	CCONJ
dti-1329	8	35	other	other	ADJ
dti-1329	8	36	known	know	VERB
dti-1329	8	37	ferric	ferric	ADJ
dti-1329	8	38	-	-	PUNCT
dti-1329	8	39	siderophore	siderophore	NOUN
dti-1329	8	40	receptors	receptor	NOUN
dti-1329	8	41	.	.	PUNCT
dti-1329	9	1	this	this	DET
dti-1329	9	2	protein	protein	NOUN
dti-1329	9	3	appears	appear	VERB
dti-1329	9	4	to	to	PART
dti-1329	9	5	localize	localize	VERB
dti-1329	9	6	on	on	ADP
dti-1329	9	7	the	the	DET
dti-1329	9	8	cell	cell	NOUN
dti-1329	9	9	membrane	membrane	NOUN
dti-1329	9	10	and	and	CCONJ
dti-1329	9	11	is	be	AUX
dti-1329	9	12	likely	likely	ADJ
dti-1329	9	13	to	to	PART
dti-1329	9	14	be	be	AUX
dti-1329	9	15	the	the	DET
dti-1329	9	16	receptor	receptor	NOUN
dti-1329	9	17	involved	involve	VERB
dti-1329	9	18	in	in	ADP
dti-1329	9	19	the	the	DET
dti-1329	9	20	ligand	ligand	NOUN
dti-1329	9	21	exchange	exchange	NOUN
dti-1329	9	22	siderophore	siderophore	ADV
dti-1329	9	23	-	-	PUNCT
dti-1329	9	24	mediated	mediate	VERB
dti-1329	9	25	iron	iron	NOUN
dti-1329	9	26	uptake	uptake	ADJ
dti-1329	9	27	mechanism	mechanism	NOUN
dti-1329	9	28	of	of	ADP
dti-1329	9	29	a.	a.	NOUN
dti-1329	9	30	hydrophila	hydrophila	PROPN
dti-1329	9	31	.	.	PUNCT
dti-1329	10	1	it	it	PRON
dti-1329	10	2	is	be	AUX
dti-1329	10	3	expected	expect	VERB
dti-1329	10	4	that	that	SCONJ
dti-1329	10	5	this	this	DET
dti-1329	10	6	information	information	NOUN
dti-1329	10	7	may	may	AUX
dti-1329	10	8	lead	lead	VERB
dti-1329	10	9	to	to	ADP
dti-1329	10	10	the	the	DET
dti-1329	10	11	development	development	NOUN
dti-1329	10	12	of	of	ADP
dti-1329	10	13	new	new	ADJ
dti-1329	10	14	antibiotics	antibiotic	NOUN
dti-1329	10	15	targeting	target	VERB
dti-1329	10	16	either	either	CCONJ
dti-1329	10	17	nsr1	nsr1	PROPN
dti-1329	10	18	or	or	CCONJ
dti-1329	10	19	its	its	PRON
dti-1329	10	20	gene	gene	NOUN
dti-1329	10	21	product	product	NOUN
dti-1329	10	22	for	for	ADP
dti-1329	10	23	use	use	NOUN
dti-1329	10	24	in	in	ADP
dti-1329	10	25	controlling	control	VERB
dti-1329	10	26	a.	a.	NOUN
dti-1329	10	27	hydrophila	hydrophila	PROPN
dti-1329	10	28	infection	infection	NOUN
dti-1329	10	29	.	.	PUNCT
dti-1329	11	1	keywords	keyword	NOUN
dti-1329	11	2	:	:	PUNCT
dti-1329	11	3	ferric	ferric	ADJ
dti-1329	11	4	iron	iron	NOUN
dti-1329	11	5	,	,	PUNCT
dti-1329	11	6	iron	iron	NOUN
dti-1329	11	7	uptake	uptake	NOUN
dti-1329	11	8	,	,	PUNCT
dti-1329	11	9	bacterial	bacterial	ADJ
dti-1329	11	10	virulence	virulence	NOUN
dti-1329	11	11	,	,	PUNCT
dti-1329	11	12	pathogenicity	pathogenicity	NOUN
dti-1329	11	13	,	,	PUNCT
dti-1329	11	14	infection	infection	NOUN
dti-1329	11	15	introduction	introduction	NOUN
dti-1329	11	16	iron	iron	NOUN
dti-1329	11	17	is	be	AUX
dti-1329	11	18	necessary	necessary	ADJ
dti-1329	11	19	for	for	ADP
dti-1329	11	20	many	many	ADJ
dti-1329	11	21	of	of	ADP
dti-1329	11	22	the	the	DET
dti-1329	11	23	critical	critical	ADJ
dti-1329	11	24	biochemical	biochemical	ADJ
dti-1329	11	25	processes	process	NOUN
dti-1329	11	26	in	in	ADP
dti-1329	11	27	bacterial	bacterial	ADJ
dti-1329	11	28	growth	growth	NOUN
dti-1329	11	29	and	and	CCONJ
dti-1329	11	30	metabolism	metabolism	NOUN
dti-1329	11	31	.	.	PUNCT
dti-1329	12	1	although	although	SCONJ
dti-1329	12	2	iron	iron	NOUN
dti-1329	12	3	is	be	AUX
dti-1329	12	4	a	a	DET
dti-1329	12	5	relatively	relatively	ADV
dti-1329	12	6	abundant	abundant	ADJ
dti-1329	12	7	element	element	NOUN
dti-1329	12	8	,	,	PUNCT
dti-1329	12	9	its	its	PRON
dti-1329	12	10	bioavailability	bioavailability	NOUN
dti-1329	12	11	is	be	AUX
dti-1329	12	12	severely	severely	ADV
dti-1329	12	13	limited	limit	VERB
dti-1329	12	14	due	due	ADP
dti-1329	12	15	to	to	ADP
dti-1329	12	16	its	its	PRON
dti-1329	12	17	low	low	ADJ
dti-1329	12	18	solubility	solubility	NOUN
dti-1329	12	19	(	(	PUNCT
dti-1329	12	20	apostol	apostol	PROPN
dti-1329	12	21	et	et	PROPN
dti-1329	12	22	al	al	PROPN
dti-1329	12	23	.	.	PROPN
dti-1329	12	24	2005	2005	NUM
dti-1329	12	25	)	)	PUNCT
dti-1329	12	26	.	.	PUNCT
dti-1329	13	1	to	to	PART
dti-1329	13	2	overcome	overcome	VERB
dti-1329	13	3	this	this	DET
dti-1329	13	4	problem	problem	NOUN
dti-1329	13	5	,	,	PUNCT
dti-1329	13	6	bacteria	bacteria	NOUN
dti-1329	13	7	secrete	secrete	VERB
dti-1329	13	8	low	low	ADJ
dti-1329	13	9	molecular	molecular	ADJ
dti-1329	13	10	weight	weight	NOUN
dti-1329	13	11	fe(iii)chelating	fe(iii)chelating	NOUN
dti-1329	13	12	compounds	compound	NOUN
dti-1329	13	13	known	know	VERB
dti-1329	13	14	as	as	ADP
dti-1329	13	15	siderophores	siderophore	NOUN
dti-1329	13	16	to	to	PART
dti-1329	13	17	assist	assist	VERB
dti-1329	13	18	in	in	ADP
dti-1329	13	19	iron	iron	NOUN
dti-1329	13	20	acquisition	acquisition	NOUN
dti-1329	13	21	.	.	PUNCT
dti-1329	14	1	these	these	DET
dti-1329	14	2	siderophores	siderophore	NOUN
dti-1329	14	3	form	form	VERB
dti-1329	14	4	complexes	complex	NOUN
dti-1329	14	5	with	with	ADP
dti-1329	14	6	extracellular	extracellular	ADJ
dti-1329	14	7	iron	iron	NOUN
dti-1329	14	8	and	and	CCONJ
dti-1329	14	9	are	be	AUX
dti-1329	14	10	generally	generally	ADV
dti-1329	14	11	transported	transport	VERB
dti-1329	14	12	into	into	ADP
dti-1329	14	13	the	the	DET
dti-1329	14	14	bacterial	bacterial	ADJ
dti-1329	14	15	periplasm	periplasm	NOUN
dti-1329	14	16	via	via	ADP
dti-1329	14	17	membrane	membrane	NOUN
dti-1329	14	18	transport	transport	NOUN
dti-1329	14	19	proteins	protein	NOUN
dti-1329	14	20	(	(	PUNCT
dti-1329	14	21	stintzi	stintzi	VERB
dti-1329	14	22	et	et	PROPN
dti-1329	14	23	al	al	PROPN
dti-1329	14	24	.	.	PROPN
dti-1329	14	25	2000	2000	NUM
dti-1329	14	26	)	)	PUNCT
dti-1329	14	27	.	.	PUNCT
dti-1329	15	1	the	the	DET
dti-1329	15	2	ability	ability	NOUN
dti-1329	15	3	of	of	ADP
dti-1329	15	4	bacteria	bacteria	NOUN
dti-1329	15	5	to	to	PART
dti-1329	15	6	scavenge	scavenge	VERB
dti-1329	15	7	iron	iron	NOUN
dti-1329	15	8	sources	source	NOUN
dti-1329	15	9	from	from	ADP
dti-1329	15	10	the	the	DET
dti-1329	15	11	environment	environment	NOUN
dti-1329	15	12	has	have	AUX
dti-1329	15	13	been	be	AUX
dti-1329	15	14	shown	show	VERB
dti-1329	15	15	to	to	PART
dti-1329	15	16	be	be	AUX
dti-1329	15	17	a	a	DET
dti-1329	15	18	signifi	signifi	NOUN
dti-1329	15	19	ca	can	AUX
dti-1329	15	20	nt	not	PART
dti-1329	15	21	factor	factor	VERB
dti-1329	15	22	in	in	ADP
dti-1329	15	23	bacterial	bacterial	ADJ
dti-1329	15	24	survival	survival	NOUN
dti-1329	15	25	,	,	PUNCT
dti-1329	15	26	as	as	ADV
dti-1329	15	27	well	well	ADV
dti-1329	15	28	as	as	ADP
dti-1329	15	29	in	in	ADP
dti-1329	15	30	bacterial	bacterial	ADJ
dti-1329	15	31	pathogenicity	pathogenicity	NOUN
dti-1329	15	32	(	(	PUNCT
dti-1329	15	33	payne	payne	PROPN
dti-1329	15	34	and	and	CCONJ
dti-1329	15	35	finkelstein	finkelstein	PROPN
dti-1329	15	36	,	,	PUNCT
dti-1329	15	37	1978	1978	NUM
dti-1329	15	38	)	)	PUNCT
dti-1329	15	39	.	.	PUNCT
dti-1329	16	1	therefore	therefore	ADV
dti-1329	16	2	,	,	PUNCT
dti-1329	16	3	siderophore	siderophore	ADV
dti-1329	16	4	-	-	PUNCT
dti-1329	16	5	mediated	mediate	VERB
dti-1329	16	6	iron	iron	NOUN
dti-1329	16	7	acquisition	acquisition	NOUN
dti-1329	16	8	systems	system	NOUN
dti-1329	16	9	play	play	VERB
dti-1329	16	10	a	a	DET
dti-1329	16	11	central	central	ADJ
dti-1329	16	12	role	role	NOUN
dti-1329	16	13	in	in	ADP
dti-1329	16	14	the	the	DET
dti-1329	16	15	progression	progression	NOUN
dti-1329	16	16	of	of	ADP
dti-1329	16	17	bacterial	bacterial	ADJ
dti-1329	16	18	infection	infection	NOUN
dti-1329	16	19	(	(	PUNCT
dti-1329	16	20	stintzi	stintzi	VERB
dti-1329	16	21	et	et	PROPN
dti-1329	16	22	al	al	PROPN
dti-1329	16	23	.	.	PROPN
dti-1329	16	24	2000	2000	NUM
dti-1329	16	25	;	;	PUNCT
dti-1329	16	26	wooldridge	wooldridge	PROPN
dti-1329	16	27	and	and	CCONJ
dti-1329	16	28	williams	williams	PROPN
dti-1329	16	29	,	,	PUNCT
dti-1329	16	30	1993	1993	NUM
dti-1329	16	31	)	)	PUNCT
dti-1329	16	32	.	.	PUNCT
dti-1329	17	1	recently	recently	ADV
dti-1329	17	2	,	,	PUNCT
dti-1329	17	3	members	member	NOUN
dti-1329	17	4	of	of	ADP
dti-1329	17	5	the	the	DET
dti-1329	17	6	genus	genus	NOUN
dti-1329	17	7	aeromonas	aeromona	NOUN
dti-1329	17	8	have	have	AUX
dti-1329	17	9	drawn	draw	VERB
dti-1329	17	10	increased	increase	VERB
dti-1329	17	11	interest	interest	NOUN
dti-1329	17	12	as	as	ADP
dti-1329	17	13	human	human	ADJ
dti-1329	17	14	pathogens	pathogen	NOUN
dti-1329	17	15	(	(	PUNCT
dti-1329	17	16	janda	janda	PROPN
dti-1329	17	17	and	and	CCONJ
dti-1329	17	18	abbott	abbott	PROPN
dti-1329	17	19	,	,	PUNCT
dti-1329	17	20	1998	1998	NUM
dti-1329	17	21	)	)	PUNCT
dti-1329	17	22	.	.	PUNCT
dti-1329	18	1	in	in	ADP
dti-1329	18	2	particular	particular	ADJ
dti-1329	18	3	,	,	PUNCT
dti-1329	18	4	the	the	DET
dti-1329	18	5	bacterium	bacterium	NOUN
dti-1329	18	6	aeromonas	aeromonas	PROPN
dti-1329	18	7	hydrophila	hydrophila	PROPN
dti-1329	18	8	has	have	AUX
dti-1329	18	9	been	be	AUX
dti-1329	18	10	reported	report	VERB
dti-1329	18	11	to	to	PART
dti-1329	18	12	cause	cause	VERB
dti-1329	18	13	a	a	DET
dti-1329	18	14	multitude	multitude	NOUN
dti-1329	18	15	of	of	ADP
dti-1329	18	16	human	human	ADJ
dti-1329	18	17	diseases	disease	NOUN
dti-1329	18	18	,	,	PUNCT
dti-1329	18	19	including	include	VERB
dti-1329	18	20	wound	wound	NOUN
dti-1329	18	21	infections	infection	NOUN
dti-1329	18	22	,	,	PUNCT
dti-1329	18	23	septicemia	septicemia	NOUN
dti-1329	18	24	,	,	PUNCT
dti-1329	18	25	and	and	CCONJ
dti-1329	18	26	diarrhea	diarrhea	NOUN
dti-1329	18	27	(	(	PUNCT
dti-1329	18	28	agger	agger	NOUN
dti-1329	18	29	et	et	PROPN
dti-1329	18	30	al	al	PROPN
dti-1329	18	31	.	.	PROPN
dti-1329	18	32	1985	1985	NUM
dti-1329	18	33	)	)	PUNCT
dti-1329	18	34	.	.	PUNCT
dti-1329	19	1	iron	iron	NOUN
dti-1329	19	2	transport	transport	NOUN
dti-1329	19	3	in	in	ADP
dti-1329	19	4	a.	a.	NOUN
dti-1329	19	5	hydrophila	hydrophila	PROPN
dti-1329	19	6	has	have	AUX
dti-1329	19	7	been	be	AUX
dti-1329	19	8	shown	show	VERB
dti-1329	19	9	to	to	PART
dti-1329	19	10	occur	occur	VERB
dti-1329	19	11	via	via	ADP
dti-1329	19	12	a	a	DET
dti-1329	19	13	single	single	ADJ
dti-1329	19	14	membrane	membrane	NOUN
dti-1329	19	15	-	-	PUNCT
dti-1329	19	16	bound	bind	VERB
dti-1329	19	17	siderophore	siderophore	ADJ
dti-1329	19	18	receptor	receptor	NOUN
dti-1329	19	19	that	that	PRON
dti-1329	19	20	is	be	AUX
dti-1329	19	21	able	able	ADJ
dti-1329	19	22	to	to	PART
dti-1329	19	23	recognize	recognize	VERB
dti-1329	19	24	a	a	DET
dti-1329	19	25	broad	broad	ADJ
dti-1329	19	26	range	range	NOUN
dti-1329	19	27	of	of	ADP
dti-1329	19	28	siderophores	siderophore	NOUN
dti-1329	19	29	,	,	PUNCT
dti-1329	19	30	utilizing	utilize	VERB
dti-1329	19	31	a	a	DET
dti-1329	19	32	ligand	ligand	ADJ
dti-1329	19	33	exchange	exchange	NOUN
dti-1329	19	34	uptake	uptake	ADJ
dti-1329	19	35	mechanism	mechanism	NOUN
dti-1329	19	36	(	(	PUNCT
dti-1329	19	37	stintzi	stintzi	VERB
dti-1329	19	38	et	et	PROPN
dti-1329	19	39	al	al	PROPN
dti-1329	19	40	.	.	PROPN
dti-1329	19	41	2000	2000	NUM
dti-1329	19	42	)	)	PUNCT
dti-1329	19	43	.	.	PUNCT
dti-1329	20	1	however	however	ADV
dti-1329	20	2	,	,	PUNCT
dti-1329	20	3	the	the	DET
dti-1329	20	4	genes	gene	NOUN
dti-1329	20	5	involved	involve	VERB
dti-1329	20	6	in	in	ADP
dti-1329	20	7	this	this	DET
dti-1329	20	8	iron	iron	NOUN
dti-1329	20	9	uptake	uptake	ADJ
dti-1329	20	10	mechanism	mechanism	NOUN
dti-1329	20	11	have	have	AUX
dti-1329	20	12	not	not	PART
dti-1329	20	13	been	be	AUX
dti-1329	20	14	reported	report	VERB
dti-1329	20	15	or	or	CCONJ
dti-1329	20	16	characterized	characterize	VERB
dti-1329	20	17	to	to	ADP
dti-1329	20	18	date	date	NOUN
dti-1329	20	19	.	.	PUNCT
dti-1329	21	1	in	in	ADP
dti-1329	21	2	the	the	DET
dti-1329	21	3	current	current	ADJ
dti-1329	21	4	paper	paper	NOUN
dti-1329	21	5	we	we	PRON
dti-1329	21	6	identify	identify	VERB
dti-1329	21	7	and	and	CCONJ
dti-1329	21	8	characterize	characterize	VERB
dti-1329	21	9	a	a	DET
dti-1329	21	10	novel	novel	ADJ
dti-1329	21	11	gene	gene	NOUN
dti-1329	21	12	from	from	ADP
dti-1329	21	13	a.	a.	PROPN
dti-1329	21	14	hydrophila	hydrophila	PROPN
dti-1329	21	15	,	,	PUNCT
dti-1329	21	16	nsr1	nsr1	PROPN
dti-1329	21	17	,	,	PUNCT
dti-1329	21	18	encoding	encode	VERB
dti-1329	21	19	a	a	DET
dti-1329	21	20	putative	putative	ADJ
dti-1329	21	21	membrane	membrane	NOUN
dti-1329	21	22	receptor	receptor	NOUN
dti-1329	21	23	protein	protein	NOUN
dti-1329	21	24	likely	likely	ADV
dti-1329	21	25	involved	involve	VERB
dti-1329	21	26	in	in	ADP
dti-1329	21	27	siderophore	siderophore	ADV
dti-1329	21	28	-	-	PUNCT
dti-1329	21	29	mediated	mediate	VERB
dti-1329	21	30	iron	iron	NOUN
dti-1329	21	31	uptake	uptake	NOUN
dti-1329	21	32	.	.	PUNCT
dti-1329	22	1	the	the	DET
dti-1329	22	2	gene	gene	NOUN
dti-1329	22	3	product	product	NOUN
dti-1329	22	4	exhibits	exhibit	VERB
dti-1329	22	5	a	a	DET
dti-1329	22	6	high	high	ADJ
dti-1329	22	7	degree	degree	NOUN
dti-1329	22	8	of	of	ADP
dti-1329	22	9	homology	homology	NOUN
dti-1329	22	10	to	to	ADP
dti-1329	22	11	the	the	DET
dti-1329	22	12	fhua	fhua	NOUN
dti-1329	22	13	protein	protein	NOUN
dti-1329	22	14	,	,	PUNCT
dti-1329	22	15	which	which	PRON
dti-1329	22	16	encodes	encode	VERB
dti-1329	22	17	an	an	DET
dti-1329	22	18	outer	outer	ADJ
dti-1329	22	19	membraneassociated	membraneassociate	VERB
dti-1329	22	20	ferric	ferric	ADJ
dti-1329	22	21	-	-	PUNCT
dti-1329	22	22	siderophore	siderophore	NOUN
dti-1329	22	23	receptor	receptor	NOUN
dti-1329	22	24	in	in	ADP
dti-1329	22	25	many	many	ADJ
dti-1329	22	26	bacteria	bacteria	NOUN
dti-1329	22	27	(	(	PUNCT
dti-1329	22	28	coulton	coulton	PROPN
dti-1329	22	29	et	et	PROPN
dti-1329	22	30	al	al	PROPN
dti-1329	22	31	.	.	PROPN
dti-1329	22	32	1986	1986	NUM
dti-1329	22	33	)	)	PUNCT
dti-1329	22	34	.	.	PUNCT
dti-1329	23	1	further	further	ADJ
dti-1329	23	2	investigation	investigation	NOUN
dti-1329	23	3	into	into	ADP
dti-1329	23	4	the	the	DET
dti-1329	23	5	structure	structure	NOUN
dti-1329	23	6	and	and	CCONJ
dti-1329	23	7	function	function	NOUN
dti-1329	23	8	of	of	ADP
dti-1329	23	9	the	the	DET
dti-1329	23	10	protein	protein	NOUN
dti-1329	23	11	product	product	NOUN
dti-1329	23	12	of	of	ADP
dti-1329	23	13	nsr1	nsr1	PROPN
dti-1329	23	14	may	may	AUX
dti-1329	23	15	elucidate	elucidate	VERB
dti-1329	23	16	the	the	DET
dti-1329	23	17	iron	iron	NOUN
dti-1329	23	18	acquisition	acquisition	NOUN
dti-1329	23	19	mechanism	mechanism	NOUN
dti-1329	23	20	of	of	ADP
dti-1329	23	21	a.	a.	NOUN
dti-1329	23	22	hydrophila	hydrophila	PROPN
dti-1329	23	23	and	and	CCONJ
dti-1329	23	24	may	may	AUX
dti-1329	23	25	provide	provide	VERB
dti-1329	23	26	insight	insight	NOUN
dti-1329	23	27	into	into	ADP
dti-1329	23	28	the	the	DET
dti-1329	23	29	pathogenesis	pathogenesis	NOUN
dti-1329	23	30	of	of	ADP
dti-1329	23	31	a.	a.	NOUN
dti-1329	23	32	hydrophila	hydrophila	PROPN
dti-1329	23	33	infection	infection	NOUN
dti-1329	23	34	in	in	ADP
dti-1329	23	35	humans	human	NOUN
dti-1329	23	36	.	.	PUNCT
dti-1329	24	1	materials	material	NOUN
dti-1329	24	2	and	and	CCONJ
dti-1329	24	3	methods	method	NOUN
dti-1329	24	4	data	datum	NOUN
dti-1329	24	5	mining	mine	VERB
dti-1329	24	6	the	the	DET
dti-1329	24	7	tigr	tigr	ADJ
dti-1329	24	8	database	database	NOUN
dti-1329	24	9	(	(	PUNCT
dti-1329	24	10	www.tigr.org	www.tigr.org	X
dti-1329	24	11	)	)	PUNCT
dti-1329	24	12	was	be	AUX
dti-1329	24	13	mined	mine	VERB
dti-1329	24	14	for	for	ADP
dti-1329	24	15	genomic	genomic	ADJ
dti-1329	24	16	data	datum	NOUN
dti-1329	24	17	,	,	PUNCT
dti-1329	24	18	and	and	CCONJ
dti-1329	24	19	the	the	DET
dti-1329	24	20	novel	novel	ADJ
dti-1329	24	21	gene	gene	NOUN
dti-1329	24	22	sequence	sequence	NOUN
dti-1329	24	23	was	be	AUX
dti-1329	24	24	derived	derive	VERB
dti-1329	24	25	from	from	ADP
dti-1329	24	26	the	the	DET
dti-1329	24	27	unfi	unfi	ADJ
dti-1329	24	28	nished	nishe	VERB
dti-1329	24	29	genome	genome	NOUN
dti-1329	24	30	of	of	ADP
dti-1329	24	31	a.	a.	NOUN
dti-1329	24	32	hydrophila	hydrophila	PROPN
dti-1329	24	33	,	,	PUNCT
dti-1329	24	34	contig	contig	PROPN
dti-1329	24	35	.	.	PROPN
dti-1329	25	1	1047085923793	1047085923793	NUM
dti-1329	25	2	(	(	PUNCT
dti-1329	25	3	5'-ggccttctgt	5'-ggccttctgt	NUM
dti-1329	25	4	…	…	SYM
dti-1329	25	5	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN
dti-1329	25	6	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN
dti-1329	25	7	32	32	NUM
dti-1329	25	8	tsen	tsen	ADJ
dti-1329	25	9	drug	drug	NOUN
dti-1329	25	10	target	target	NOUN
dti-1329	25	11	insights	insight	NOUN
dti-1329	25	12	2008:3	2008:3	NUM
dti-1329	25	13	gttgcgagc-3	gttgcgagc-3	NOUN
dti-1329	25	14	'	'	PUNCT
dti-1329	25	15	)	)	PUNCT
dti-1329	25	16	,	,	PUNCT
dti-1329	25	17	by	by	ADP
dti-1329	25	18	selection	selection	NOUN
dti-1329	25	19	of	of	ADP
dti-1329	25	20	the	the	DET
dti-1329	25	21	sequence	sequence	NOUN
dti-1329	25	22	encoding	encode	VERB
dti-1329	25	23	the	the	DET
dti-1329	25	24	longest	long	ADV
dti-1329	25	25	observed	observe	VERB
dti-1329	25	26	translated	translate	VERB
dti-1329	25	27	open	open	ADJ
dti-1329	25	28	reading	reading	NOUN
dti-1329	25	29	frame	frame	NOUN
dti-1329	25	30	within	within	ADP
dti-1329	25	31	the	the	DET
dti-1329	25	32	contig	contig	NOUN
dti-1329	25	33	(	(	PUNCT
dti-1329	25	34	sixframe	sixframe	PROPN
dti-1329	25	35	program	program	NOUN
dti-1329	25	36	,	,	PUNCT
dti-1329	25	37	biology	biology	NOUN
dti-1329	25	38	workbench	workbench	NOUN
dti-1329	25	39	,	,	PUNCT
dti-1329	25	40	san	san	PROPN
dti-1329	25	41	diego	diego	PROPN
dti-1329	25	42	,	,	PUNCT
dti-1329	25	43	ca	ca	PROPN
dti-1329	25	44	,	,	PUNCT
dti-1329	25	45	http://workbench.sdsc.edu	http://workbench.sdsc.edu	PROPN
dti-1329	25	46	)	)	PUNCT
dti-1329	25	47	.	.	PUNCT
dti-1329	26	1	this	this	PRON
dti-1329	26	2	yielded	yield	VERB
dti-1329	26	3	a	a	DET
dti-1329	26	4	2106	2106	NUM
dti-1329	26	5	-	-	PUNCT
dti-1329	26	6	bp	bp	PROPN
dti-1329	26	7	dna	dna	PROPN
dti-1329	26	8	sequence	sequence	NOUN
dti-1329	26	9	encoding	encode	VERB
dti-1329	26	10	the	the	DET
dti-1329	26	11	putative	putative	ADJ
dti-1329	26	12	protein	protein	NOUN
dti-1329	26	13	(	(	PUNCT
dti-1329	26	14	fig	fig	NOUN
dti-1329	26	15	.	.	PUNCT
dti-1329	26	16	1	1	NUM
dti-1329	26	17	)	)	PUNCT
dti-1329	26	18	.	.	PUNCT
dti-1329	27	1	sequence	sequence	NOUN
dti-1329	27	2	/	/	SYM
dti-1329	27	3	product	product	NOUN
dti-1329	27	4	analysis	analysis	NOUN
dti-1329	27	5	database	database	NOUN
dti-1329	27	6	comparisons	comparison	NOUN
dti-1329	27	7	to	to	ADP
dti-1329	27	8	known	know	VERB
dti-1329	27	9	nucleotide	nucleotide	NOUN
dti-1329	27	10	sequences	sequence	NOUN
dti-1329	27	11	and	and	CCONJ
dti-1329	27	12	proteins	protein	NOUN
dti-1329	27	13	were	be	AUX
dti-1329	27	14	made	make	VERB
dti-1329	27	15	by	by	ADP
dti-1329	27	16	using	use	VERB
dti-1329	27	17	the	the	DET
dti-1329	27	18	rapid	rapid	ADJ
dti-1329	27	19	sequence	sequence	NOUN
dti-1329	27	20	database	database	NOUN
dti-1329	27	21	query	query	NOUN
dti-1329	27	22	programs	program	NOUN
dti-1329	27	23	blastp	blastp	VERB
dti-1329	27	24	,	,	PUNCT
dti-1329	27	25	blastn	blastn	NOUN
dti-1329	27	26	,	,	PUNCT
dti-1329	27	27	and	and	CCONJ
dti-1329	27	28	tblastn	tblastn	PROPN
dti-1329	27	29	(	(	PUNCT
dti-1329	27	30	genbank	genbank	NOUN
dti-1329	27	31	,	,	PUNCT
dti-1329	27	32	national	national	ADJ
dti-1329	27	33	center	center	NOUN
dti-1329	27	34	for	for	ADP
dti-1329	27	35	biotechnology	biotechnology	NOUN
dti-1329	27	36	information	information	NOUN
dti-1329	27	37	,	,	PUNCT
dti-1329	27	38	bethesda	bethesda	PROPN
dti-1329	27	39	,	,	PUNCT
dti-1329	27	40	md	md	PROPN
dti-1329	27	41	,	,	PUNCT
dti-1329	27	42	http://www.ncbi.nlm.nih.gov/blast	http://www.ncbi.nlm.nih.gov/blast	ADJ
dti-1329	27	43	)	)	PUNCT
dti-1329	27	44	.	.	PUNCT
dti-1329	28	1	protein	protein	NOUN
dti-1329	28	2	crystal	crystal	NOUN
dti-1329	28	3	structure	structure	NOUN
dti-1329	28	4	prediction	prediction	NOUN
dti-1329	28	5	and	and	CCONJ
dti-1329	28	6	hydropathy	hydropathy	ADJ
dti-1329	28	7	plots	plot	NOUN
dti-1329	28	8	were	be	AUX
dti-1329	28	9	carried	carry	VERB
dti-1329	28	10	out	out	ADP
dti-1329	28	11	using	use	VERB
dti-1329	28	12	publicly	publicly	ADV
dti-1329	28	13	available	available	ADJ
dti-1329	28	14	online	online	ADJ
dti-1329	28	15	programs	program	NOUN
dti-1329	28	16	including	include	VERB
dti-1329	28	17	the	the	DET
dti-1329	28	18	3d	3d	NUM
dti-1329	28	19	-	-	PUNCT
dti-1329	28	20	jigsaw	jigsaw	NOUN
dti-1329	28	21	protein	protein	NOUN
dti-1329	28	22	comparative	comparative	ADJ
dti-1329	28	23	modeling	modeling	NOUN
dti-1329	28	24	server	server	NOUN
dti-1329	28	25	(	(	PUNCT
dti-1329	28	26	http://www.bmm	http://www.bmm	PROPN
dti-1329	28	27	.	.	PUNCT
dti-1329	28	28	icnet.uk/servers/3djigsaw	icnet.uk/servers/3djigsaw	NOUN
dti-1329	28	29	)	)	PUNCT
dti-1329	28	30	,	,	PUNCT
dti-1329	28	31	the	the	DET
dti-1329	28	32	expasy	expasy	ADJ
dti-1329	28	33	proteomics	proteomic	NOUN
dti-1329	28	34	server	server	NOUN
dti-1329	28	35	(	(	PUNCT
dti-1329	28	36	www.expasy.org	www.expasy.org	NUM
dti-1329	28	37	)	)	PUNCT
dti-1329	28	38	,	,	PUNCT
dti-1329	28	39	and	and	CCONJ
dti-1329	28	40	biology	biology	NOUN
dti-1329	28	41	workbench	workbench	NOUN
dti-1329	28	42	.	.	PUNCT
dti-1329	29	1	results	result	NOUN
dti-1329	29	2	and	and	CCONJ
dti-1329	29	3	discussion	discussion	NOUN
dti-1329	29	4	dna	dna	NOUN
dti-1329	29	5	sequence	sequence	NOUN
dti-1329	29	6	analysis	analysis	NOUN
dti-1329	29	7	of	of	ADP
dti-1329	29	8	nsr1	nsr1	PROPN
dti-1329	29	9	the	the	DET
dti-1329	29	10	nucleotide	nucleotide	ADJ
dti-1329	29	11	sequence	sequence	NOUN
dti-1329	29	12	of	of	ADP
dti-1329	29	13	nsr1	nsr1	PROPN
dti-1329	29	14	was	be	AUX
dti-1329	29	15	compared	compare	VERB
dti-1329	29	16	to	to	ADP
dti-1329	29	17	known	know	VERB
dti-1329	29	18	dna	dna	NOUN
dti-1329	29	19	sequences	sequence	NOUN
dti-1329	29	20	in	in	ADP
dti-1329	29	21	the	the	DET
dti-1329	29	22	genbank	genbank	PROPN
dti-1329	29	23	database	database	NOUN
dti-1329	29	24	with	with	ADP
dti-1329	29	25	blastn	blastn	NOUN
dti-1329	29	26	(	(	PUNCT
dti-1329	29	27	genbank	genbank	PROPN
dti-1329	29	28	,	,	PUNCT
dti-1329	29	29	ncbi	ncbi	PROPN
dti-1329	29	30	)	)	PUNCT
dti-1329	29	31	and	and	CCONJ
dti-1329	29	32	no	no	DET
dti-1329	29	33	signifi	signifi	NOUN
dti-1329	29	34	ca	can	AUX
dti-1329	29	35	nt	not	PART
dti-1329	29	36	similarities	similarity	NOUN
dti-1329	29	37	were	be	AUX
dti-1329	29	38	found	find	VERB
dti-1329	29	39	.	.	PUNCT
dti-1329	30	1	this	this	PRON
dti-1329	30	2	is	be	AUX
dti-1329	30	3	not	not	PART
dti-1329	30	4	surprising	surprising	ADJ
dti-1329	30	5	,	,	PUNCT
dti-1329	30	6	given	give	VERB
dti-1329	30	7	the	the	DET
dti-1329	30	8	generally	generally	ADV
dti-1329	30	9	high	high	ADJ
dti-1329	30	10	mutation	mutation	NOUN
dti-1329	30	11	rate	rate	NOUN
dti-1329	30	12	in	in	ADP
dti-1329	30	13	bacteria	bacteria	NOUN
dti-1329	30	14	and	and	CCONJ
dti-1329	30	15	the	the	DET
dti-1329	30	16	evolutionary	evolutionary	ADJ
dti-1329	30	17	time	time	NOUN
dti-1329	30	18	span	span	NOUN
dti-1329	30	19	of	of	ADP
dti-1329	30	20	iron	iron	NOUN
dti-1329	30	21	uptake	uptake	ADJ
dti-1329	30	22	mechanisms	mechanism	NOUN
dti-1329	30	23	which	which	PRON
dti-1329	30	24	were	be	AUX
dti-1329	30	25	crucial	crucial	ADJ
dti-1329	30	26	for	for	ADP
dti-1329	30	27	survival	survival	NOUN
dti-1329	30	28	in	in	ADP
dti-1329	30	29	the	the	DET
dti-1329	30	30	earliest	early	ADJ
dti-1329	30	31	known	know	VERB
dti-1329	30	32	organisms	organism	NOUN
dti-1329	30	33	.	.	PUNCT
dti-1329	31	1	the	the	DET
dti-1329	31	2	nucleotide	nucleotide	ADJ
dti-1329	31	3	sequence	sequence	NOUN
dti-1329	31	4	of	of	ADP
dti-1329	31	5	nsr1	nsr1	PROPN
dti-1329	31	6	contains	contain	VERB
dti-1329	31	7	a	a	DET
dti-1329	31	8	high	high	ADJ
dti-1329	31	9	gc	gc	PROPN
dti-1329	31	10	content	content	NOUN
dti-1329	31	11	(	(	PUNCT
dti-1329	31	12	61.8	61.8	NUM
dti-1329	31	13	%	%	NOUN
dti-1329	31	14	)	)	PUNCT
dti-1329	31	15	characteristic	characteristic	NOUN
dti-1329	31	16	of	of	ADP
dti-1329	31	17	gene	gene	NOUN
dti-1329	31	18	-	-	PUNCT
dti-1329	31	19	containing	contain	VERB
dti-1329	31	20	genomic	genomic	ADJ
dti-1329	31	21	regions	region	NOUN
dti-1329	31	22	(	(	PUNCT
dti-1329	31	23	nastats	nastat	NOUN
dti-1329	31	24	,	,	PUNCT
dti-1329	31	25	biology	biology	NOUN
dti-1329	31	26	workbench	workbench	NOUN
dti-1329	31	27	)	)	PUNCT
dti-1329	31	28	.	.	PUNCT
dti-1329	32	1	characterization	characterization	NOUN
dti-1329	32	2	of	of	ADP
dti-1329	32	3	the	the	DET
dti-1329	32	4	nsr1	nsr1	PROPN
dti-1329	32	5	gene	gene	NOUN
dti-1329	32	6	product	product	NOUN
dti-1329	32	7	the	the	DET
dti-1329	32	8	dna	dna	PROPN
dti-1329	32	9	sequence	sequence	NOUN
dti-1329	32	10	of	of	ADP
dti-1329	32	11	nsr1	nsr1	PROPN
dti-1329	32	12	was	be	AUX
dti-1329	32	13	translated	translate	VERB
dti-1329	32	14	and	and	CCONJ
dti-1329	32	15	found	find	VERB
dti-1329	32	16	to	to	PART
dti-1329	32	17	contain	contain	VERB
dti-1329	32	18	an	an	DET
dti-1329	32	19	open	open	ADJ
dti-1329	32	20	reading	reading	NOUN
dti-1329	32	21	frame	frame	NOUN
dti-1329	32	22	of	of	ADP
dti-1329	32	23	702	702	NUM
dti-1329	32	24	amino	amino	ADJ
dti-1329	32	25	acids	acid	NOUN
dti-1329	32	26	encoding	encode	VERB
dti-1329	32	27	the	the	DET
dti-1329	32	28	putative	putative	ADJ
dti-1329	32	29	protein	protein	NOUN
dti-1329	32	30	(	(	PUNCT
dti-1329	32	31	sixframe	sixframe	PROPN
dti-1329	32	32	program	program	NOUN
dti-1329	32	33	,	,	PUNCT
dti-1329	32	34	biology	biology	NOUN
dti-1329	32	35	workbench	workbench	NOUN
dti-1329	32	36	)	)	PUNCT
dti-1329	32	37	.	.	PUNCT
dti-1329	33	1	the	the	DET
dti-1329	33	2	molecular	molecular	ADJ
dti-1329	33	3	mass	mass	NOUN
dti-1329	33	4	of	of	ADP
dti-1329	33	5	the	the	DET
dti-1329	33	6	resulting	result	VERB
dti-1329	33	7	protein	protein	NOUN
dti-1329	33	8	was	be	AUX
dti-1329	33	9	predicted	predict	VERB
dti-1329	33	10	to	to	PART
dti-1329	33	11	be	be	AUX
dti-1329	33	12	∼77.4	∼77.4	NUM
dti-1329	33	13	kda	kda	NOUN
dti-1329	33	14	(	(	PUNCT
dti-1329	33	15	expasy	expasy	ADJ
dti-1329	33	16	,	,	PUNCT
dti-1329	33	17	swiss	swiss	PROPN
dti-1329	33	18	institute	institute	PROPN
dti-1329	33	19	of	of	ADP
dti-1329	33	20	bioinformatics	bioinformatics	PROPN
dti-1329	33	21	,	,	PUNCT
dti-1329	33	22	canada	canada	PROPN
dti-1329	33	23	)	)	PUNCT
dti-1329	33	24	.	.	PUNCT
dti-1329	34	1	a	a	DET
dti-1329	34	2	kyte	kyte	PROPN
dti-1329	34	3	-	-	PUNCT
dti-1329	34	4	doolittle	doolittle	NOUN
dti-1329	34	5	hydropathy	hydropathy	ADJ
dti-1329	34	6	plot	plot	NOUN
dti-1329	34	7	indicates	indicate	VERB
dti-1329	34	8	the	the	DET
dti-1329	34	9	presence	presence	NOUN
dti-1329	34	10	of	of	ADP
dti-1329	34	11	numerous	numerous	ADJ
dti-1329	34	12	potential	potential	ADJ
dti-1329	34	13	membranespanning	membranespanne	VERB
dti-1329	34	14	regions	region	NOUN
dti-1329	34	15	in	in	ADP
dti-1329	34	16	the	the	DET
dti-1329	34	17	predicted	predict	VERB
dti-1329	34	18	polypeptide	polypeptide	NOUN
dti-1329	34	19	,	,	PUNCT
dti-1329	34	20	suggesting	suggest	VERB
dti-1329	34	21	that	that	SCONJ
dti-1329	34	22	the	the	DET
dti-1329	34	23	putative	putative	ADJ
dti-1329	34	24	protein	protein	NOUN
dti-1329	34	25	may	may	AUX
dti-1329	34	26	be	be	AUX
dti-1329	34	27	localized	localize	VERB
dti-1329	34	28	on	on	ADP
dti-1329	34	29	the	the	DET
dti-1329	34	30	cell	cell	NOUN
dti-1329	34	31	membrane	membrane	NOUN
dti-1329	34	32	(	(	PUNCT
dti-1329	34	33	kyte	kyte	PROPN
dti-1329	34	34	and	and	CCONJ
dti-1329	34	35	doolittle	doolittle	PROPN
dti-1329	34	36	,	,	PUNCT
dti-1329	34	37	1982	1982	NUM
dti-1329	34	38	)	)	PUNCT
dti-1329	34	39	(	(	PUNCT
dti-1329	34	40	fig	fig	NOUN
dti-1329	34	41	.	.	PUNCT
dti-1329	35	1	2	2	NUM
dti-1329	35	2	)	)	PUNCT
dti-1329	35	3	.	.	PUNCT
dti-1329	36	1	this	this	PRON
dti-1329	36	2	is	be	AUX
dti-1329	36	3	supported	support	VERB
dti-1329	36	4	by	by	ADP
dti-1329	36	5	the	the	DET
dti-1329	36	6	high	high	ADJ
dti-1329	36	7	percentage	percentage	NOUN
dti-1329	36	8	of	of	ADP
dti-1329	36	9	hydrophobic	hydrophobic	NOUN
dti-1329	36	10	residues	residue	NOUN
dti-1329	36	11	(	(	PUNCT
dti-1329	36	12	%	%	INTJ
dti-1329	36	13	lvifm	lvifm	NOUN
dti-1329	36	14	=	=	SYM
dti-1329	36	15	23.8	23.8	NUM
dti-1329	36	16	%	%	NOUN
dti-1329	36	17	)	)	PUNCT
dti-1329	36	18	present	present	ADJ
dti-1329	36	19	in	in	ADP
dti-1329	36	20	the	the	DET
dti-1329	36	21	sequence	sequence	NOUN
dti-1329	36	22	(	(	PUNCT
dti-1329	36	23	saps	sap	NOUN
dti-1329	36	24	program	program	NOUN
dti-1329	36	25	,	,	PUNCT
dti-1329	36	26	biology	biology	NOUN
dti-1329	36	27	workbench	workbench	NOUN
dti-1329	36	28	)	)	PUNCT
dti-1329	36	29	.	.	PUNCT
dti-1329	37	1	individual	individual	ADJ
dti-1329	37	2	amino	amino	NOUN
dti-1329	37	3	acid	acid	NOUN
dti-1329	37	4	composition	composition	NOUN
dti-1329	37	5	of	of	ADP
dti-1329	37	6	the	the	DET
dti-1329	37	7	polypeptide	polypeptide	NOUN
dti-1329	37	8	includes	include	VERB
dti-1329	37	9	a	a	DET
dti-1329	37	10	high	high	ADJ
dti-1329	37	11	percentage	percentage	NOUN
dti-1329	37	12	of	of	ADP
dti-1329	37	13	glycine	glycine	NOUN
dti-1329	37	14	(	(	PUNCT
dti-1329	37	15	9.5	9.5	NUM
dti-1329	37	16	%	%	NOUN
dti-1329	37	17	)	)	PUNCT
dti-1329	37	18	and	and	CCONJ
dti-1329	37	19	leucine	leucine	NOUN
dti-1329	37	20	(	(	PUNCT
dti-1329	37	21	9.6	9.6	NUM
dti-1329	37	22	%	%	NOUN
dti-1329	37	23	)	)	PUNCT
dti-1329	37	24	residues	residue	NOUN
dti-1329	37	25	(	(	PUNCT
dti-1329	37	26	aastats	aastat	NOUN
dti-1329	37	27	program	program	NOUN
dti-1329	37	28	,	,	PUNCT
dti-1329	37	29	biology	biology	NOUN
dti-1329	37	30	workbench	workbench	NOUN
dti-1329	37	31	)	)	PUNCT
dti-1329	37	32	,	,	PUNCT
dti-1329	37	33	and	and	CCONJ
dti-1329	37	34	further	further	ADJ
dti-1329	37	35	analysis	analysis	NOUN
dti-1329	37	36	of	of	ADP
dti-1329	37	37	the	the	DET
dti-1329	37	38	polypeptide	polypeptide	ADJ
dti-1329	37	39	revealed	reveal	VERB
dti-1329	37	40	alternating	alternate	VERB
dti-1329	37	41	glycine	glycine	NOUN
dti-1329	37	42	-	-	PUNCT
dti-1329	37	43	rich	rich	ADJ
dti-1329	37	44	and	and	CCONJ
dti-1329	37	45	leucine	leucine	NOUN
dti-1329	37	46	-	-	PUNCT
dti-1329	37	47	rich	rich	ADJ
dti-1329	37	48	regions	region	NOUN
dti-1329	37	49	.	.	PUNCT
dti-1329	38	1	this	this	DET
dti-1329	38	2	observed	observe	VERB
dti-1329	38	3	pattern	pattern	NOUN
dti-1329	38	4	of	of	ADP
dti-1329	38	5	alternating	alternate	VERB
dti-1329	38	6	hydrophilic	hydrophilic	ADJ
dti-1329	38	7	and	and	CCONJ
dti-1329	38	8	hydrophobic	hydrophobic	NOUN
dti-1329	38	9	regions	region	NOUN
dti-1329	38	10	is	be	AUX
dti-1329	38	11	also	also	ADV
dti-1329	38	12	seen	see	VERB
dti-1329	38	13	in	in	ADP
dti-1329	38	14	other	other	ADJ
dti-1329	38	15	bacterial	bacterial	ADJ
dti-1329	38	16	ferric	ferric	ADJ
dti-1329	38	17	-	-	PUNCT
dti-1329	38	18	siderophore	siderophore	NOUN
dti-1329	38	19	receptors	receptor	NOUN
dti-1329	38	20	(	(	PUNCT
dti-1329	38	21	newton	newton	PROPN
dti-1329	38	22	et	et	PROPN
dti-1329	38	23	al	al	PROPN
dti-1329	38	24	.	.	PROPN
dti-1329	38	25	1997	1997	NUM
dti-1329	38	26	)	)	PUNCT
dti-1329	38	27	;	;	PUNCT
dti-1329	38	28	hydrophilic	hydrophilic	ADJ
dti-1329	38	29	regions	region	NOUN
dti-1329	38	30	constitute	constitute	VERB
dti-1329	38	31	surface	surface	NOUN
dti-1329	38	32	loops	loop	NOUN
dti-1329	38	33	and	and	CCONJ
dti-1329	38	34	may	may	AUX
dti-1329	38	35	facilitate	facilitate	VERB
dti-1329	38	36	siderophore	siderophore	ADV
dti-1329	38	37	binding	bind	VERB
dti-1329	38	38	in	in	ADP
dti-1329	38	39	the	the	DET
dti-1329	38	40	extracellular	extracellular	ADJ
dti-1329	38	41	compartment	compartment	NOUN
dti-1329	38	42	,	,	PUNCT
dti-1329	38	43	while	while	SCONJ
dti-1329	38	44	hydrophobic	hydrophobic	ADJ
dti-1329	38	45	regions	region	NOUN
dti-1329	38	46	anchor	anchor	VERB
dti-1329	38	47	the	the	DET
dti-1329	38	48	protein	protein	NOUN
dti-1329	38	49	to	to	ADP
dti-1329	38	50	the	the	DET
dti-1329	38	51	cell	cell	NOUN
dti-1329	38	52	membrane	membrane	NOUN
dti-1329	38	53	.	.	PUNCT
dti-1329	39	1	the	the	DET
dti-1329	39	2	protein	protein	NOUN
dti-1329	39	3	is	be	AUX
dti-1329	39	4	predicted	predict	VERB
dti-1329	39	5	to	to	PART
dti-1329	39	6	be	be	AUX
dti-1329	39	7	slightly	slightly	ADV
dti-1329	39	8	negatively	negatively	ADV
dti-1329	39	9	charged	charge	VERB
dti-1329	39	10	in	in	ADP
dti-1329	39	11	general	general	ADJ
dti-1329	39	12	(	(	PUNCT
dti-1329	39	13	%	%	INTJ
dti-1329	39	14	kr	kr	PROPN
dti-1329	39	15	—	—	PUNCT
dti-1329	39	16	ed	ed	NOUN
dti-1329	39	17	=	=	PUNCT
dti-1329	39	18	−3.4	−3.4	NOUN
dti-1329	39	19	%	%	NOUN
dti-1329	39	20	)	)	PUNCT
dti-1329	39	21	;	;	PUNCT
dti-1329	39	22	however	however	ADV
dti-1329	39	23	,	,	PUNCT
dti-1329	39	24	no	no	DET
dti-1329	39	25	charge	charge	NOUN
dti-1329	39	26	clusters	cluster	NOUN
dti-1329	39	27	were	be	AUX
dti-1329	39	28	predicted	predict	VERB
dti-1329	39	29	(	(	PUNCT
dti-1329	39	30	saps	sap	NOUN
dti-1329	39	31	program	program	NOUN
dti-1329	39	32	,	,	PUNCT
dti-1329	39	33	biology	biology	NOUN
dti-1329	39	34	workbench	workbench	NOUN
dti-1329	39	35	)	)	PUNCT
dti-1329	39	36	.	.	PUNCT
dti-1329	40	1	protein	protein	NOUN
dti-1329	40	2	pi	pi	NOUN
dti-1329	40	3	was	be	AUX
dti-1329	40	4	estimated	estimate	VERB
dti-1329	40	5	to	to	PART
dti-1329	40	6	be	be	AUX
dti-1329	40	7	∼4.94	∼4.94	VERB
dti-1329	40	8	,	,	PUNCT
dti-1329	40	9	in	in	ADP
dti-1329	40	10	agreement	agreement	NOUN
dti-1329	40	11	with	with	ADP
dti-1329	40	12	the	the	DET
dti-1329	40	13	environment	environment	NOUN
dti-1329	40	14	necessary	necessary	ADJ
dti-1329	40	15	for	for	ADP
dti-1329	40	16	the	the	DET
dti-1329	40	17	acidifi	acidifi	PROPN
dti-1329	40	18	cation	cation	NOUN
dti-1329	40	19	process	process	NOUN
dti-1329	40	20	and	and	CCONJ
dti-1329	40	21	removal	removal	NOUN
dti-1329	40	22	of	of	ADP
dti-1329	40	23	iron	iron	NOUN
dti-1329	40	24	within	within	ADP
dti-1329	40	25	the	the	DET
dti-1329	40	26	barrel	barrel	NOUN
dti-1329	40	27	of	of	ADP
dti-1329	40	28	the	the	DET
dti-1329	40	29	receptor	receptor	NOUN
dti-1329	40	30	in	in	ADP
dti-1329	40	31	a	a	DET
dti-1329	40	32	ligand	ligand	ADJ
dti-1329	40	33	exchange	exchange	NOUN
dti-1329	40	34	iron	iron	NOUN
dti-1329	40	35	uptake	uptake	ADJ
dti-1329	40	36	mechanism	mechanism	NOUN
dti-1329	40	37	(	(	PUNCT
dti-1329	40	38	stintzi	stintzi	VERB
dti-1329	40	39	et	et	PROPN
dti-1329	40	40	al	al	PROPN
dti-1329	40	41	.	.	PROPN
dti-1329	40	42	2000	2000	NUM
dti-1329	40	43	)	)	PUNCT
dti-1329	40	44	.	.	PUNCT
dti-1329	41	1	the	the	DET
dti-1329	41	2	homology	homology	NOUN
dti-1329	41	3	of	of	ADP
dti-1329	41	4	the	the	DET
dti-1329	41	5	putative	putative	ADJ
dti-1329	41	6	protein	protein	NOUN
dti-1329	41	7	to	to	ADP
dti-1329	41	8	currently	currently	ADV
dti-1329	41	9	known	know	VERB
dti-1329	41	10	proteins	protein	NOUN
dti-1329	41	11	was	be	AUX
dti-1329	41	12	characterized	characterize	VERB
dti-1329	41	13	with	with	ADP
dti-1329	41	14	blastp	blastp	PROPN
dti-1329	41	15	(	(	PUNCT
dti-1329	41	16	genbank	genbank	PROPN
dti-1329	41	17	,	,	PUNCT
dti-1329	41	18	ncbi	ncbi	PROPN
dti-1329	41	19	)	)	PUNCT
dti-1329	41	20	.	.	PUNCT
dti-1329	42	1	the	the	DET
dti-1329	42	2	fhua	fhua	NOUN
dti-1329	42	3	protein	protein	NOUN
dti-1329	42	4	and	and	CCONJ
dti-1329	42	5	similar	similar	ADJ
dti-1329	42	6	iron	iron	NOUN
dti-1329	42	7	uptake	uptake	ADJ
dti-1329	42	8	proteins	protein	NOUN
dti-1329	42	9	from	from	ADP
dti-1329	42	10	various	various	ADJ
dti-1329	42	11	bacteria	bacteria	NOUN
dti-1329	42	12	were	be	AUX
dti-1329	42	13	obtained	obtain	VERB
dti-1329	42	14	and	and	CCONJ
dti-1329	42	15	aligned	align	VERB
dti-1329	42	16	using	use	VERB
dti-1329	42	17	the	the	DET
dti-1329	42	18	algorithm	algorithm	NOUN
dti-1329	42	19	of	of	ADP
dti-1329	42	20	thompson	thompson	PROPN
dti-1329	42	21	et	et	PROPN
dti-1329	42	22	al	al	PROPN
dti-1329	42	23	.	.	PUNCT
dti-1329	43	1	(	(	PUNCT
dti-1329	43	2	thompson	thompson	PROPN
dti-1329	43	3	et	et	PROPN
dti-1329	43	4	al	al	PROPN
dti-1329	43	5	.	.	PROPN
dti-1329	43	6	1994	1994	NUM
dti-1329	43	7	)	)	PUNCT
dti-1329	43	8	(	(	PUNCT
dti-1329	43	9	clustalw	clustalw	PROPN
dti-1329	43	10	program	program	NOUN
dti-1329	43	11	,	,	PUNCT
dti-1329	43	12	biology	biology	NOUN
dti-1329	43	13	workbench	workbench	NOUN
dti-1329	43	14	)	)	PUNCT
dti-1329	43	15	.	.	PUNCT
dti-1329	44	1	in	in	ADP
dti-1329	44	2	the	the	DET
dti-1329	44	3	multiple	multiple	ADJ
dti-1329	44	4	sequence	sequence	NOUN
dti-1329	44	5	alignment	alignment	NOUN
dti-1329	44	6	(	(	PUNCT
dti-1329	44	7	fig	fig	NOUN
dti-1329	44	8	.	.	PUNCT
dti-1329	45	1	3	3	NUM
dti-1329	45	2	)	)	PUNCT
dti-1329	45	3	,	,	PUNCT
dti-1329	45	4	the	the	DET
dti-1329	45	5	conserved	conserve	VERB
dti-1329	45	6	residues	residue	NOUN
dti-1329	45	7	are	be	AUX
dti-1329	45	8	distributed	distribute	VERB
dti-1329	45	9	along	along	ADP
dti-1329	45	10	the	the	DET
dti-1329	45	11	entire	entire	ADJ
dti-1329	45	12	length	length	NOUN
dti-1329	45	13	of	of	ADP
dti-1329	45	14	the	the	DET
dti-1329	45	15	polypeptide	polypeptide	NOUN
dti-1329	45	16	,	,	PUNCT
dti-1329	45	17	suggesting	suggest	VERB
dti-1329	45	18	a	a	DET
dti-1329	45	19	strong	strong	ADJ
dti-1329	45	20	evolutionary	evolutionary	ADJ
dti-1329	45	21	pressure	pressure	NOUN
dti-1329	45	22	to	to	PART
dti-1329	45	23	preserve	preserve	VERB
dti-1329	45	24	amino	amino	ADJ
dti-1329	45	25	acids	acid	NOUN
dti-1329	45	26	at	at	ADP
dti-1329	45	27	specifi	specifi	PROPN
dti-1329	45	28	c	c	PROPN
dti-1329	45	29	positions	position	NOUN
dti-1329	45	30	for	for	ADP
dti-1329	45	31	structural	structural	ADJ
dti-1329	45	32	and/or	and/or	CCONJ
dti-1329	45	33	functional	functional	ADJ
dti-1329	45	34	reasons	reason	NOUN
dti-1329	45	35	.	.	PUNCT
dti-1329	46	1	ferric	ferric	ADJ
dti-1329	46	2	-	-	PUNCT
dti-1329	46	3	siderophore	siderophore	NOUN
dti-1329	46	4	receptors	receptor	NOUN
dti-1329	46	5	in	in	ADP
dti-1329	46	6	general	general	ADJ
dti-1329	46	7	are	be	AUX
dti-1329	46	8	characterized	characterize	VERB
dti-1329	46	9	by	by	ADP
dti-1329	46	10	evolutionarily	evolutionarily	ADV
dti-1329	46	11	conserved	conserve	VERB
dti-1329	46	12	surface	surface	NOUN
dti-1329	46	13	loops	loop	NOUN
dti-1329	46	14	and	and	CCONJ
dti-1329	46	15	anti	anti	ADJ
dti-1329	46	16	-	-	ADJ
dti-1329	46	17	parallel	parallel	ADJ
dti-1329	46	18	β	β	NOUN
dti-1329	46	19	-	-	NOUN
dti-1329	46	20	barrels	barrel	NOUN
dti-1329	46	21	;	;	PUNCT
dti-1329	46	22	the	the	DET
dti-1329	46	23	former	former	ADJ
dti-1329	46	24	is	be	AUX
dti-1329	46	25	required	require	VERB
dti-1329	46	26	for	for	ADP
dti-1329	46	27	interaction	interaction	NOUN
dti-1329	46	28	with	with	ADP
dti-1329	46	29	iron	iron	NOUN
dti-1329	46	30	-	-	PUNCT
dti-1329	46	31	loaded	load	VERB
dti-1329	46	32	siderophores	siderophore	NOUN
dti-1329	46	33	in	in	ADP
dti-1329	46	34	the	the	DET
dti-1329	46	35	extracellular	extracellular	ADJ
dti-1329	46	36	compartment	compartment	NOUN
dti-1329	46	37	,	,	PUNCT
dti-1329	46	38	and	and	CCONJ
dti-1329	46	39	the	the	DET
dti-1329	46	40	latter	latter	ADJ
dti-1329	46	41	constitutes	constitute	VERB
dti-1329	46	42	the	the	DET
dti-1329	46	43	iron	iron	NOUN
dti-1329	46	44	removal	removal	NOUN
dti-1329	46	45	acidifi	acidifi	PROPN
dti-1329	46	46	cation	cation	NOUN
dti-1329	46	47	site	site	NOUN
dti-1329	46	48	within	within	ADP
dti-1329	46	49	the	the	DET
dti-1329	46	50	receptor	receptor	NOUN
dti-1329	46	51	(	(	PUNCT
dti-1329	46	52	stintzi	stintzi	VERB
dti-1329	46	53	et	et	PROPN
dti-1329	46	54	al	al	PROPN
dti-1329	46	55	.	.	PROPN
dti-1329	46	56	2000	2000	NUM
dti-1329	46	57	;	;	PUNCT
dti-1329	47	1	newton	newton	PROPN
dti-1329	47	2	et	et	PROPN
dti-1329	47	3	al	al	PROPN
dti-1329	47	4	.	.	PROPN
dti-1329	47	5	1997	1997	NUM
dti-1329	47	6	)	)	PUNCT
dti-1329	47	7	.	.	PUNCT
dti-1329	48	1	the	the	DET
dti-1329	48	2	predicted	predict	VERB
dti-1329	48	3	crystal	crystal	NOUN
dti-1329	48	4	structure	structure	NOUN
dti-1329	48	5	of	of	ADP
dti-1329	48	6	the	the	DET
dti-1329	48	7	putative	putative	ADJ
dti-1329	48	8	protein	protein	NOUN
dti-1329	48	9	(	(	PUNCT
dti-1329	48	10	fig	fig	NOUN
dti-1329	48	11	.	.	PUNCT
dti-1329	48	12	4	4	NUM
dti-1329	48	13	)	)	PUNCT
dti-1329	48	14	was	be	AUX
dti-1329	48	15	modeled	model	VERB
dti-1329	48	16	using	use	VERB
dti-1329	48	17	the	the	DET
dti-1329	48	18	3djigsaw	3djigsaw	NUM
dti-1329	48	19	protein	protein	NOUN
dti-1329	48	20	comparative	comparative	ADJ
dti-1329	48	21	modeling	modeling	NOUN
dti-1329	48	22	server	server	NOUN
dti-1329	48	23	(	(	PUNCT
dti-1329	48	24	bates	bate	NOUN
dti-1329	48	25	et	et	PROPN
dti-1329	48	26	al	al	PROPN
dti-1329	48	27	.	.	PROPN
dti-1329	48	28	2001	2001	NUM
dti-1329	48	29	;	;	PUNCT
dti-1329	48	30	bates	bate	NOUN
dti-1329	48	31	and	and	CCONJ
dti-1329	48	32	sternberg	sternberg	PROPN
dti-1329	48	33	,	,	PUNCT
dti-1329	48	34	1999	1999	NUM
dti-1329	48	35	;	;	PUNCT
dti-1329	48	36	contrerasmoreira	contrerasmoreira	NOUN
dti-1329	48	37	and	and	CCONJ
dti-1329	48	38	bates	bate	NOUN
dti-1329	48	39	,	,	PUNCT
dti-1329	48	40	2002	2002	NUM
dti-1329	48	41	)	)	PUNCT
dti-1329	48	42	and	and	CCONJ
dti-1329	48	43	contains	contain	VERB
dti-1329	48	44	an	an	DET
dti-1329	48	45	33	33	NUM
dti-1329	48	46	evidence	evidence	NOUN
dti-1329	48	47	of	of	ADP
dti-1329	48	48	a	a	DET
dti-1329	48	49	novel	novel	ADJ
dti-1329	48	50	gene	gene	NOUN
dti-1329	48	51	from	from	ADP
dti-1329	48	52	aeromonas	aeromonas	PROPN
dti-1329	48	53	hydrophila	hydrophila	PROPN
dti-1329	48	54	drug	drug	NOUN
dti-1329	48	55	target	target	NOUN
dti-1329	48	56	insights	insight	NOUN
dti-1329	48	57	2008:3	2008:3	NUM
dti-1329	48	58	figure	figure	NOUN
dti-1329	48	59	1	1	NUM
dti-1329	48	60	.	.	PUNCT
dti-1329	48	61	dna	dna	PROPN
dti-1329	48	62	sequence	sequence	NOUN
dti-1329	48	63	of	of	ADP
dti-1329	48	64	nsr1	nsr1	PROPN
dti-1329	48	65	and	and	CCONJ
dti-1329	48	66	its	its	PRON
dti-1329	48	67	translated	translate	VERB
dti-1329	48	68	amino	amino	NOUN
dti-1329	48	69	acid	acid	NOUN
dti-1329	48	70	sequence	sequence	NOUN
dti-1329	48	71	.	.	PUNCT
dti-1329	49	1	only	only	ADV
dti-1329	49	2	those	those	DET
dti-1329	49	3	nucleotides	nucleotide	NOUN
dti-1329	49	4	encoding	encode	VERB
dti-1329	49	5	the	the	DET
dti-1329	49	6	predicted	predict	VERB
dti-1329	49	7	polypeptide	polypeptide	NOUN
dti-1329	49	8	are	be	AUX
dti-1329	49	9	numbered	number	VERB
dti-1329	49	10	.	.	PUNCT
dti-1329	50	1	34	34	NUM
dti-1329	50	2	tsen	tsen	ADJ
dti-1329	50	3	drug	drug	NOUN
dti-1329	50	4	target	target	NOUN
dti-1329	50	5	insights	insight	NOUN
dti-1329	50	6	2008:3	2008:3	NUM
dti-1329	50	7	anti	anti	ADJ
dti-1329	50	8	-	-	ADJ
dti-1329	50	9	parallel	parallel	ADJ
dti-1329	50	10	β	β	NOUN
dti-1329	50	11	-	-	NOUN
dti-1329	50	12	barrel	barrel	NOUN
dti-1329	50	13	and	and	CCONJ
dti-1329	50	14	a	a	DET
dti-1329	50	15	globular	globular	ADJ
dti-1329	50	16	domain	domain	NOUN
dti-1329	50	17	that	that	PRON
dti-1329	50	18	forms	form	VERB
dti-1329	50	19	surface	surface	NOUN
dti-1329	50	20	loops	loop	NOUN
dti-1329	50	21	and	and	CCONJ
dti-1329	50	22	folds	fold	NOUN
dti-1329	50	23	down	down	ADP
dti-1329	50	24	into	into	ADP
dti-1329	50	25	the	the	DET
dti-1329	50	26	β	β	NOUN
dti-1329	50	27	-	-	PUNCT
dti-1329	50	28	barrel	barrel	NOUN
dti-1329	50	29	—	—	PUNCT
dti-1329	50	30	two	two	NUM
dti-1329	50	31	features	feature	NOUN
dti-1329	50	32	thought	think	VERB
dti-1329	50	33	to	to	PART
dti-1329	50	34	be	be	AUX
dti-1329	50	35	common	common	ADJ
dti-1329	50	36	to	to	ADP
dti-1329	50	37	all	all	DET
dti-1329	50	38	ferric	ferric	ADJ
dti-1329	50	39	-	-	PUNCT
dti-1329	50	40	siderophore	siderophore	NOUN
dti-1329	50	41	receptors	receptor	NOUN
dti-1329	50	42	(	(	PUNCT
dti-1329	50	43	stintzi	stintzi	VERB
dti-1329	50	44	et	et	PROPN
dti-1329	50	45	al	al	PROPN
dti-1329	50	46	.	.	PROPN
dti-1329	50	47	2000	2000	NUM
dti-1329	50	48	)	)	PUNCT
dti-1329	50	49	.	.	PUNCT
dti-1329	51	1	the	the	DET
dti-1329	51	2	interior	interior	NOUN
dti-1329	51	3	of	of	ADP
dti-1329	51	4	the	the	DET
dti-1329	51	5	β	β	NOUN
dti-1329	51	6	-	-	NOUN
dti-1329	51	7	barrel	barrel	NOUN
dti-1329	51	8	represents	represent	VERB
dti-1329	51	9	the	the	DET
dti-1329	51	10	site	site	NOUN
dti-1329	51	11	where	where	SCONJ
dti-1329	51	12	iron	iron	NOUN
dti-1329	51	13	is	be	AUX
dti-1329	51	14	removed	remove	VERB
dti-1329	51	15	from	from	ADP
dti-1329	51	16	iron	iron	NOUN
dti-1329	51	17	-	-	PUNCT
dti-1329	51	18	loaded	load	VERB
dti-1329	51	19	siderophores	siderophore	NOUN
dti-1329	51	20	,	,	PUNCT
dti-1329	51	21	and	and	CCONJ
dti-1329	51	22	the	the	DET
dti-1329	51	23	n	n	CCONJ
dti-1329	51	24	-	-	PUNCT
dti-1329	51	25	terminal	terminal	ADJ
dti-1329	51	26	domain	domain	NOUN
dti-1329	51	27	predominantly	predominantly	ADV
dti-1329	51	28	consists	consist	VERB
dti-1329	51	29	of	of	ADP
dti-1329	51	30	surface	surface	NOUN
dti-1329	51	31	loops	loop	NOUN
dti-1329	51	32	that	that	PRON
dti-1329	51	33	appear	appear	VERB
dti-1329	51	34	to	to	PART
dti-1329	51	35	be	be	AUX
dti-1329	51	36	hydrophilic	hydrophilic	ADJ
dti-1329	51	37	in	in	ADP
dti-1329	51	38	nature	nature	NOUN
dti-1329	51	39	and	and	CCONJ
dti-1329	51	40	that	that	PRON
dti-1329	51	41	may	may	AUX
dti-1329	51	42	facilitate	facilitate	VERB
dti-1329	51	43	binding	bind	VERB
dti-1329	51	44	of	of	ADP
dti-1329	51	45	hydrophilic	hydrophilic	ADJ
dti-1329	51	46	ferric	ferric	ADJ
dti-1329	51	47	-	-	PUNCT
dti-1329	51	48	siderophores	siderophore	NOUN
dti-1329	51	49	to	to	ADP
dti-1329	51	50	the	the	DET
dti-1329	51	51	receptor	receptor	NOUN
dti-1329	51	52	.	.	PUNCT
dti-1329	52	1	a.	a.	NOUN
dti-1329	52	2	hydrophila	hydrophila	PROPN
dti-1329	52	3	has	have	AUX
dti-1329	52	4	been	be	AUX
dti-1329	52	5	shown	show	VERB
dti-1329	52	6	to	to	PART
dti-1329	52	7	acquire	acquire	VERB
dti-1329	52	8	iron	iron	NOUN
dti-1329	52	9	via	via	ADP
dti-1329	52	10	a	a	DET
dti-1329	52	11	ligand	ligand	ADJ
dti-1329	52	12	exchange	exchange	NOUN
dti-1329	52	13	model	model	NOUN
dti-1329	52	14	(	(	PUNCT
dti-1329	52	15	stintzi	stintzi	VERB
dti-1329	52	16	et	et	PROPN
dti-1329	52	17	al	al	PROPN
dti-1329	52	18	.	.	PROPN
dti-1329	52	19	2000	2000	NUM
dti-1329	52	20	)	)	PUNCT
dti-1329	52	21	,	,	PUNCT
dti-1329	52	22	in	in	ADP
dti-1329	52	23	which	which	PRON
dti-1329	52	24	a	a	DET
dti-1329	52	25	siderophore	siderophore	NOUN
dti-1329	52	26	is	be	AUX
dti-1329	52	27	initially	initially	ADV
dti-1329	52	28	bound	bind	VERB
dti-1329	52	29	to	to	ADP
dti-1329	52	30	the	the	DET
dti-1329	52	31	receptor	receptor	NOUN
dti-1329	52	32	as	as	ADP
dti-1329	52	33	a	a	DET
dti-1329	52	34	siderophore	siderophore	ADJ
dti-1329	52	35	-	-	PUNCT
dti-1329	52	36	receptor	receptor	NOUN
dti-1329	52	37	complex	complex	NOUN
dti-1329	52	38	.	.	PUNCT
dti-1329	53	1	when	when	SCONJ
dti-1329	53	2	a	a	DET
dti-1329	53	3	second	second	ADJ
dti-1329	53	4	,	,	PUNCT
dti-1329	53	5	iron	iron	NOUN
dti-1329	53	6	-	-	PUNCT
dti-1329	53	7	loaded	load	VERB
dti-1329	53	8	siderophore	siderophore	NOUN
dti-1329	53	9	is	be	AUX
dti-1329	53	10	in	in	ADP
dti-1329	53	11	close	close	ADJ
dti-1329	53	12	proximity	proximity	NOUN
dti-1329	53	13	of	of	ADP
dti-1329	53	14	the	the	DET
dti-1329	53	15	receptor	receptor	NOUN
dti-1329	53	16	,	,	PUNCT
dti-1329	53	17	iron	iron	NOUN
dti-1329	53	18	is	be	AUX
dti-1329	53	19	likely	likely	ADV
dti-1329	53	20	removed	remove	VERB
dti-1329	53	21	from	from	ADP
dti-1329	53	22	the	the	DET
dti-1329	53	23	second	second	ADJ
dti-1329	53	24	siderophore	siderophore	NOUN
dti-1329	53	25	via	via	ADP
dti-1329	53	26	a	a	DET
dti-1329	53	27	ph	ph	ADJ
dti-1329	53	28	gradient	gradient	NOUN
dti-1329	53	29	within	within	ADP
dti-1329	53	30	the	the	DET
dti-1329	53	31	barrel	barrel	NOUN
dti-1329	53	32	of	of	ADP
dti-1329	53	33	the	the	DET
dti-1329	53	34	receptor	receptor	NOUN
dti-1329	53	35	(	(	PUNCT
dti-1329	53	36	stintzi	stintzi	VERB
dti-1329	53	37	et	et	PROPN
dti-1329	53	38	al	al	PROPN
dti-1329	53	39	.	.	PROPN
dti-1329	53	40	2000	2000	NUM
dti-1329	53	41	)	)	PUNCT
dti-1329	53	42	.	.	PUNCT
dti-1329	54	1	this	this	PRON
dti-1329	54	2	results	result	VERB
dti-1329	54	3	in	in	ADP
dti-1329	54	4	a	a	DET
dti-1329	54	5	protonation	protonation	NOUN
dti-1329	54	6	/	/	SYM
dti-1329	54	7	deprotonation	deprotonation	NOUN
dti-1329	54	8	reaction	reaction	NOUN
dti-1329	54	9	,	,	PUNCT
dti-1329	54	10	and	and	CCONJ
dti-1329	54	11	the	the	DET
dti-1329	54	12	iron	iron	NOUN
dti-1329	54	13	is	be	AUX
dti-1329	54	14	donated	donate	VERB
dti-1329	54	15	to	to	ADP
dti-1329	54	16	the	the	DET
dti-1329	54	17	initial	initial	ADJ
dti-1329	54	18	siderophore	siderophore	NOUN
dti-1329	54	19	which	which	PRON
dti-1329	54	20	translocates	translocate	VERB
dti-1329	54	21	from	from	ADP
dti-1329	54	22	the	the	DET
dti-1329	54	23	membrane	membrane	NOUN
dti-1329	54	24	to	to	ADP
dti-1329	54	25	the	the	DET
dti-1329	54	26	periplasmic	periplasmic	ADJ
dti-1329	54	27	space	space	NOUN
dti-1329	54	28	.	.	PUNCT
dti-1329	55	1	the	the	DET
dti-1329	55	2	second	second	ADJ
dti-1329	55	3	siderophore	siderophore	ADV
dti-1329	55	4	then	then	ADV
dti-1329	55	5	binds	bind	VERB
dti-1329	55	6	to	to	ADP
dti-1329	55	7	the	the	DET
dti-1329	55	8	receptor	receptor	NOUN
dti-1329	55	9	,	,	PUNCT
dti-1329	55	10	replacing	replace	VERB
dti-1329	55	11	the	the	DET
dti-1329	55	12	initial	initial	ADJ
dti-1329	55	13	siderophore	siderophore	NOUN
dti-1329	55	14	.	.	PUNCT
dti-1329	56	1	in	in	ADP
dti-1329	56	2	the	the	DET
dti-1329	56	3	predicted	predict	VERB
dti-1329	56	4	structure	structure	NOUN
dti-1329	56	5	of	of	ADP
dti-1329	56	6	the	the	DET
dti-1329	56	7	nsr1	nsr1	PROPN
dti-1329	56	8	gene	gene	NOUN
dti-1329	56	9	product	product	NOUN
dti-1329	56	10	,	,	PUNCT
dti-1329	56	11	the	the	DET
dti-1329	56	12	interior	interior	NOUN
dti-1329	56	13	of	of	ADP
dti-1329	56	14	the	the	DET
dti-1329	56	15	protein	protein	NOUN
dti-1329	56	16	is	be	AUX
dti-1329	56	17	enclosed	enclose	VERB
dti-1329	56	18	by	by	ADP
dti-1329	56	19	β	β	NOUN
dti-1329	56	20	-	-	NOUN
dti-1329	56	21	sheets	sheet	NOUN
dti-1329	56	22	and	and	CCONJ
dti-1329	56	23	is	be	AUX
dti-1329	56	24	likely	likely	ADJ
dti-1329	56	25	to	to	PART
dti-1329	56	26	be	be	AUX
dti-1329	56	27	a	a	DET
dti-1329	56	28	suitable	suitable	ADJ
dti-1329	56	29	environment	environment	NOUN
dti-1329	56	30	for	for	ADP
dti-1329	56	31	local	local	ADJ
dti-1329	56	32	acidifi	acidifi	NOUN
dti-1329	56	33	cation	cation	NOUN
dti-1329	56	34	.	.	PUNCT
dti-1329	57	1	the	the	DET
dti-1329	57	2	hydrophilic	hydrophilic	ADJ
dti-1329	57	3	regions	region	NOUN
dti-1329	57	4	probably	probably	ADV
dti-1329	57	5	extend	extend	VERB
dti-1329	57	6	into	into	ADP
dti-1329	57	7	the	the	DET
dti-1329	57	8	extracellular	extracellular	ADJ
dti-1329	57	9	space	space	NOUN
dti-1329	57	10	to	to	PART
dti-1329	57	11	interact	interact	VERB
dti-1329	57	12	with	with	ADP
dti-1329	57	13	ferric	ferric	ADJ
dti-1329	57	14	-	-	PUNCT
dti-1329	57	15	siderophores	siderophore	NOUN
dti-1329	57	16	,	,	PUNCT
dti-1329	57	17	as	as	SCONJ
dti-1329	57	18	is	be	AUX
dti-1329	57	19	seen	see	VERB
dti-1329	57	20	with	with	ADP
dti-1329	57	21	many	many	ADJ
dti-1329	57	22	bacterial	bacterial	ADJ
dti-1329	57	23	siderophore	siderophore	ADV
dti-1329	57	24	uptake	uptake	ADJ
dti-1329	57	25	proteins	protein	NOUN
dti-1329	57	26	such	such	ADJ
dti-1329	57	27	as	as	ADP
dti-1329	57	28	fepa	fepa	NOUN
dti-1329	57	29	,	,	PUNCT
dti-1329	57	30	the	the	DET
dti-1329	57	31	enterobactin	enterobactin	NOUN
dti-1329	57	32	receptor	receptor	NOUN
dti-1329	57	33	expressed	express	VERB
dti-1329	57	34	by	by	ADP
dti-1329	57	35	e.	e.	PROPN
dti-1329	57	36	coli	coli	PROPN
dti-1329	57	37	(	(	PUNCT
dti-1329	57	38	newton	newton	PROPN
dti-1329	57	39	et	et	PROPN
dti-1329	57	40	al	al	PROPN
dti-1329	57	41	.	.	PROPN
dti-1329	57	42	1997	1997	NUM
dti-1329	57	43	)	)	PUNCT
dti-1329	57	44	.	.	PUNCT
dti-1329	58	1	bacteria	bacteria	NOUN
dti-1329	58	2	frequently	frequently	ADV
dti-1329	58	3	possess	possess	VERB
dti-1329	58	4	feedback	feedback	NOUN
dti-1329	58	5	systems	system	NOUN
dti-1329	58	6	that	that	PRON
dti-1329	58	7	upregulate	upregulate	VERB
dti-1329	58	8	or	or	CCONJ
dti-1329	58	9	downregulate	downregulate	VERB
dti-1329	58	10	the	the	DET
dti-1329	58	11	expression	expression	NOUN
dti-1329	58	12	of	of	ADP
dti-1329	58	13	certain	certain	ADJ
dti-1329	58	14	iron	iron	NOUN
dti-1329	58	15	uptake	uptake	ADJ
dti-1329	58	16	proteins	protein	NOUN
dti-1329	58	17	,	,	PUNCT
dti-1329	58	18	including	include	VERB
dti-1329	58	19	the	the	DET
dti-1329	58	20	energy	energy	NOUN
dti-1329	58	21	transducing	transduce	VERB
dti-1329	58	22	protein	protein	NOUN
dti-1329	58	23	tonb	tonb	NOUN
dti-1329	58	24	,	,	PUNCT
dti-1329	58	25	in	in	ADP
dti-1329	58	26	response	response	NOUN
dti-1329	58	27	to	to	ADP
dti-1329	58	28	environmental	environmental	ADJ
dti-1329	58	29	iron	iron	NOUN
dti-1329	58	30	levels	level	NOUN
dti-1329	58	31	(	(	PUNCT
dti-1329	58	32	beddek	beddek	NOUN
dti-1329	58	33	et	et	PROPN
dti-1329	58	34	al	al	PROPN
dti-1329	58	35	.	.	PROPN
dti-1329	58	36	2004	2004	NUM
dti-1329	58	37	)	)	PUNCT
dti-1329	58	38	.	.	PUNCT
dti-1329	59	1	however	however	ADV
dti-1329	59	2	,	,	PUNCT
dti-1329	59	3	expression	expression	NOUN
dti-1329	59	4	of	of	ADP
dti-1329	59	5	the	the	DET
dti-1329	59	6	fhua	fhua	NOUN
dti-1329	59	7	gene	gene	NOUN
dti-1329	59	8	has	have	AUX
dti-1329	59	9	been	be	AUX
dti-1329	59	10	shown	show	VERB
dti-1329	59	11	to	to	PART
dti-1329	59	12	be	be	AUX
dti-1329	59	13	unaffected	unaffected	ADJ
dti-1329	59	14	by	by	ADP
dti-1329	59	15	iron	iron	NOUN
dti-1329	59	16	conditions	condition	NOUN
dti-1329	59	17	(	(	PUNCT
dti-1329	59	18	mikael	mikael	PROPN
dti-1329	59	19	et	et	PROPN
dti-1329	59	20	al	al	PROPN
dti-1329	59	21	.	.	PROPN
dti-1329	59	22	2003	2003	NUM
dti-1329	59	23	)	)	PUNCT
dti-1329	59	24	.	.	PUNCT
dti-1329	60	1	based	base	VERB
dti-1329	60	2	upon	upon	SCONJ
dti-1329	60	3	the	the	DET
dti-1329	60	4	similarities	similarity	NOUN
dti-1329	60	5	between	between	ADP
dti-1329	60	6	the	the	DET
dti-1329	60	7	protein	protein	NOUN
dti-1329	60	8	products	product	NOUN
dti-1329	60	9	of	of	ADP
dti-1329	60	10	nsr1	nsr1	PROPN
dti-1329	60	11	and	and	CCONJ
dti-1329	60	12	fhua	fhua	PROPN
dti-1329	60	13	,	,	PUNCT
dti-1329	60	14	it	it	PRON
dti-1329	60	15	is	be	AUX
dti-1329	60	16	possible	possible	ADJ
dti-1329	60	17	that	that	SCONJ
dti-1329	60	18	expression	expression	NOUN
dti-1329	60	19	of	of	ADP
dti-1329	60	20	nsr1	nsr1	PROPN
dti-1329	60	21	may	may	AUX
dti-1329	60	22	also	also	ADV
dti-1329	60	23	be	be	AUX
dti-1329	60	24	unaffected	unaffected	ADJ
dti-1329	60	25	in	in	ADP
dti-1329	60	26	the	the	DET
dti-1329	60	27	presence	presence	NOUN
dti-1329	60	28	or	or	CCONJ
dti-1329	60	29	absence	absence	NOUN
dti-1329	60	30	of	of	ADP
dti-1329	60	31	iron	iron	NOUN
dti-1329	60	32	.	.	PUNCT
dti-1329	61	1	in	in	ADP
dti-1329	61	2	a.	a.	NOUN
dti-1329	61	3	hydrophila	hydrophila	PROPN
dti-1329	61	4	,	,	PUNCT
dti-1329	61	5	and	and	CCONJ
dti-1329	61	6	in	in	ADP
dti-1329	61	7	other	other	ADJ
dti-1329	61	8	bacteria	bacteria	NOUN
dti-1329	61	9	,	,	PUNCT
dti-1329	61	10	iron	iron	NOUN
dti-1329	61	11	-	-	PUNCT
dti-1329	61	12	dependent	dependent	ADJ
dti-1329	61	13	regulation	regulation	NOUN
dti-1329	61	14	of	of	ADP
dti-1329	61	15	iron	iron	NOUN
dti-1329	61	16	uptake	uptake	NOUN
dti-1329	61	17	occurs	occur	VERB
dti-1329	61	18	at	at	ADP
dti-1329	61	19	the	the	DET
dti-1329	61	20	level	level	NOUN
dti-1329	61	21	of	of	ADP
dti-1329	61	22	siderophore	siderophore	ADJ
dti-1329	61	23	biosynthesis	biosynthesis	NOUN
dti-1329	61	24	rather	rather	ADV
dti-1329	61	25	than	than	ADP
dti-1329	61	26	at	at	ADP
dti-1329	61	27	the	the	DET
dti-1329	61	28	level	level	NOUN
dti-1329	61	29	of	of	ADP
dti-1329	61	30	siderophore	siderophore	ADJ
dti-1329	61	31	receptor	receptor	NOUN
dti-1329	61	32	production	production	NOUN
dti-1329	61	33	(	(	PUNCT
dti-1329	61	34	stintzi	stintzi	VERB
dti-1329	61	35	et	et	PROPN
dti-1329	61	36	al	al	PROPN
dti-1329	61	37	.	.	PROPN
dti-1329	61	38	2000	2000	NUM
dti-1329	61	39	;	;	PUNCT
dti-1329	61	40	venturi	venturi	PROPN
dti-1329	61	41	et	et	PROPN
dti-1329	61	42	al	al	PROPN
dti-1329	61	43	.	.	PROPN
dti-1329	61	44	1995	1995	NUM
dti-1329	61	45	)	)	PUNCT
dti-1329	61	46	.	.	PUNCT
dti-1329	62	1	therefore	therefore	ADV
dti-1329	62	2	it	it	PRON
dti-1329	62	3	appears	appear	VERB
dti-1329	62	4	to	to	PART
dti-1329	62	5	be	be	AUX
dti-1329	62	6	advantageous	advantageous	ADJ
dti-1329	62	7	for	for	SCONJ
dti-1329	62	8	a.	a.	NOUN
dti-1329	62	9	hydrophila	hydrophila	PROPN
dti-1329	62	10	to	to	PART
dti-1329	62	11	express	express	VERB
dti-1329	62	12	nsr1	nsr1	PROPN
dti-1329	62	13	constitutively	constitutively	ADV
dti-1329	62	14	to	to	PART
dti-1329	62	15	maintain	maintain	VERB
dti-1329	62	16	a	a	DET
dti-1329	62	17	constant	constant	ADJ
dti-1329	62	18	means	mean	NOUN
dti-1329	62	19	of	of	ADP
dti-1329	62	20	iron	iron	NOUN
dti-1329	62	21	acquisition	acquisition	NOUN
dti-1329	62	22	.	.	PUNCT
dti-1329	63	1	further	further	ADJ
dti-1329	63	2	studies	study	NOUN
dti-1329	63	3	are	be	AUX
dti-1329	63	4	warranted	warrant	VERB
dti-1329	63	5	to	to	PART
dti-1329	63	6	clarify	clarify	VERB
dti-1329	63	7	the	the	DET
dti-1329	63	8	irondependent	irondependent	NOUN
dti-1329	63	9	(	(	PUNCT
dti-1329	63	10	and	and	CCONJ
dti-1329	63	11	potentially	potentially	ADV
dti-1329	63	12	iron	iron	NOUN
dti-1329	63	13	-	-	PUNCT
dti-1329	63	14	independent	independent	ADJ
dti-1329	63	15	)	)	PUNCT
dti-1329	63	16	mechanisms	mechanism	NOUN
dti-1329	63	17	by	by	ADP
dti-1329	63	18	which	which	PRON
dti-1329	63	19	nsr1	nsr1	PROPN
dti-1329	63	20	is	be	AUX
dti-1329	63	21	regulated	regulate	VERB
dti-1329	63	22	.	.	PUNCT
dti-1329	64	1	the	the	DET
dti-1329	64	2	presence	presence	NOUN
dti-1329	64	3	of	of	ADP
dti-1329	64	4	a	a	DET
dti-1329	64	5	unique	unique	ADJ
dti-1329	64	6	nsr1	nsr1	NOUN
dti-1329	64	7	-	-	PUNCT
dti-1329	64	8	driven	drive	VERB
dti-1329	64	9	siderophore	siderophore	ADJ
dti-1329	64	10	system	system	NOUN
dti-1329	64	11	has	have	VERB
dti-1329	64	12	implications	implication	NOUN
dti-1329	64	13	for	for	ADP
dti-1329	64	14	the	the	DET
dti-1329	64	15	development	development	NOUN
dti-1329	64	16	of	of	ADP
dti-1329	64	17	drugs	drug	NOUN
dti-1329	64	18	to	to	PART
dti-1329	64	19	control	control	VERB
dti-1329	64	20	a.	a.	PROPN
dti-1329	64	21	hydrophila	hydrophila	PROPN
dti-1329	64	22	.	.	PUNCT
dti-1329	65	1	since	since	SCONJ
dti-1329	65	2	the	the	DET
dti-1329	65	3	utilization	utilization	NOUN
dti-1329	65	4	of	of	ADP
dti-1329	65	5	specifi	specifi	PROPN
dti-1329	65	6	c	c	PROPN
dti-1329	65	7	siderophore	siderophore	PROPN
dti-1329	65	8	systems	system	NOUN
dti-1329	65	9	are	be	AUX
dti-1329	65	10	often	often	ADV
dti-1329	65	11	confi	confi	ADJ
dti-1329	65	12	ned	ned	ADJ
dti-1329	65	13	to	to	ADP
dti-1329	65	14	certain	certain	ADJ
dti-1329	65	15	bacteria	bacteria	NOUN
dti-1329	65	16	,	,	PUNCT
dti-1329	65	17	and	and	CCONJ
dti-1329	65	18	because	because	SCONJ
dti-1329	65	19	siderophores	siderophore	NOUN
dti-1329	65	20	often	often	ADV
dti-1329	65	21	play	play	VERB
dti-1329	65	22	a	a	DET
dti-1329	65	23	critical	critical	ADJ
dti-1329	65	24	role	role	NOUN
dti-1329	65	25	in	in	ADP
dti-1329	65	26	bacterial	bacterial	ADJ
dti-1329	65	27	growth	growth	NOUN
dti-1329	65	28	,	,	PUNCT
dti-1329	65	29	survival	survival	NOUN
dti-1329	65	30	and	and	CCONJ
dti-1329	65	31	virulence	virulence	NOUN
dti-1329	65	32	,	,	PUNCT
dti-1329	65	33	targeting	target	VERB
dti-1329	65	34	siderophore	siderophore	ADV
dti-1329	65	35	-	-	PUNCT
dti-1329	65	36	mediated	mediate	VERB
dti-1329	65	37	iron	iron	NOUN
dti-1329	65	38	uptake	uptake	NOUN
dti-1329	65	39	is	be	AUX
dti-1329	65	40	an	an	DET
dti-1329	65	41	attractive	attractive	ADJ
dti-1329	65	42	approach	approach	NOUN
dti-1329	65	43	to	to	ADP
dti-1329	65	44	antibacterial	antibacterial	ADJ
dti-1329	65	45	drug	drug	NOUN
dti-1329	65	46	development	development	NOUN
dti-1329	65	47	.	.	PUNCT
dti-1329	66	1	siderophore	siderophore	ADJ
dti-1329	66	2	-	-	PUNCT
dti-1329	66	3	antibiotic	antibiotic	ADJ
dti-1329	66	4	conjugates	conjugate	NOUN
dti-1329	66	5	,	,	PUNCT
dti-1329	66	6	called	call	VERB
dti-1329	66	7	sideromycins	sideromycin	NOUN
dti-1329	66	8	,	,	PUNCT
dti-1329	66	9	have	have	AUX
dti-1329	66	10	been	be	AUX
dti-1329	66	11	shown	show	VERB
dti-1329	66	12	to	to	PART
dti-1329	66	13	be	be	AUX
dti-1329	66	14	highly	highly	ADV
dti-1329	66	15	effective	effective	ADJ
dti-1329	66	16	at	at	ADP
dti-1329	66	17	entering	enter	VERB
dti-1329	66	18	bacteria	bacteria	NOUN
dti-1329	66	19	by	by	ADP
dti-1329	66	20	exploiting	exploit	VERB
dti-1329	66	21	natural	natural	ADJ
dti-1329	66	22	figure	figure	NOUN
dti-1329	66	23	2	2	NUM
dti-1329	66	24	.	.	PUNCT
dti-1329	66	25	hydropathy	hydropathy	ADJ
dti-1329	66	26	plot	plot	NOUN
dti-1329	66	27	of	of	ADP
dti-1329	66	28	the	the	DET
dti-1329	66	29	predicted	predict	VERB
dti-1329	66	30	polypeptide	polypeptide	NOUN
dti-1329	66	31	of	of	ADP
dti-1329	66	32	nsr1	nsr1	PROPN
dti-1329	66	33	,	,	PUNCT
dti-1329	66	34	obtained	obtain	VERB
dti-1329	66	35	using	use	VERB
dti-1329	66	36	the	the	DET
dti-1329	66	37	kyte	kyte	PROPN
dti-1329	66	38	-	-	PUNCT
dti-1329	66	39	doolittle	doolittle	NOUN
dti-1329	66	40	algorithm	algorithm	NOUN
dti-1329	66	41	and	and	CCONJ
dti-1329	66	42	hydropathy	hydropathy	ADJ
dti-1329	66	43	values	value	NOUN
dti-1329	66	44	(	(	PUNCT
dti-1329	66	45	kyte	kyte	PROPN
dti-1329	66	46	and	and	CCONJ
dti-1329	66	47	doolittle	doolittle	PROPN
dti-1329	66	48	,	,	PUNCT
dti-1329	66	49	1982	1982	NUM
dti-1329	66	50	)	)	PUNCT
dti-1329	66	51	.	.	PUNCT
dti-1329	67	1	alternating	alternate	VERB
dti-1329	67	2	regions	region	NOUN
dti-1329	67	3	of	of	ADP
dti-1329	67	4	hydrophilicity	hydrophilicity	NOUN
dti-1329	67	5	and	and	CCONJ
dti-1329	67	6	hydrophobicity	hydrophobicity	NOUN
dti-1329	67	7	are	be	AUX
dti-1329	67	8	observed	observe	VERB
dti-1329	67	9	.	.	PUNCT
dti-1329	68	1	35	35	NUM
dti-1329	68	2	evidence	evidence	NOUN
dti-1329	68	3	of	of	ADP
dti-1329	68	4	a	a	DET
dti-1329	68	5	novel	novel	ADJ
dti-1329	68	6	gene	gene	NOUN
dti-1329	68	7	from	from	ADP
dti-1329	68	8	aeromonas	aeromonas	PROPN
dti-1329	68	9	hydrophila	hydrophila	PROPN
dti-1329	68	10	drug	drug	NOUN
dti-1329	68	11	target	target	NOUN
dti-1329	68	12	insights	insight	NOUN
dti-1329	68	13	2008:3	2008:3	NUM
dti-1329	68	14	siderophore	siderophore	ADV
dti-1329	68	15	uptake	uptake	ADJ
dti-1329	68	16	mechanisms	mechanism	NOUN
dti-1329	68	17	to	to	PART
dti-1329	68	18	traverse	traverse	VERB
dti-1329	68	19	bacterial	bacterial	ADJ
dti-1329	68	20	cell	cell	NOUN
dti-1329	68	21	membranes	membrane	NOUN
dti-1329	68	22	(	(	PUNCT
dti-1329	68	23	for	for	ADP
dti-1329	68	24	a	a	DET
dti-1329	68	25	review	review	NOUN
dti-1329	68	26	,	,	PUNCT
dti-1329	68	27	see	see	VERB
dti-1329	68	28	miethke	miethke	ADJ
dti-1329	68	29	and	and	CCONJ
dti-1329	68	30	marahiel	marahiel	ADJ
dti-1329	68	31	,	,	PUNCT
dti-1329	68	32	2007	2007	NUM
dti-1329	68	33	)	)	PUNCT
dti-1329	68	34	.	.	PUNCT
dti-1329	69	1	this	this	PRON
dti-1329	69	2	could	could	AUX
dti-1329	69	3	provide	provide	VERB
dti-1329	69	4	a	a	DET
dti-1329	69	5	method	method	NOUN
dti-1329	69	6	for	for	ADP
dti-1329	69	7	specifi	specifi	PROPN
dti-1329	69	8	c	c	PROPN
dti-1329	69	9	and	and	CCONJ
dti-1329	69	10	effi	effi	PROPN
dti-1329	69	11	cient	cient	PROPN
dti-1329	69	12	drug	drug	NOUN
dti-1329	69	13	targeting	target	VERB
dti-1329	69	14	to	to	ADP
dti-1329	69	15	a.	a.	NOUN
dti-1329	69	16	hydrophila	hydrophila	PROPN
dti-1329	69	17	.	.	PUNCT
dti-1329	70	1	on	on	ADP
dti-1329	70	2	the	the	DET
dti-1329	70	3	other	other	ADJ
dti-1329	70	4	hand	hand	NOUN
dti-1329	70	5	,	,	PUNCT
dti-1329	70	6	drugs	drug	NOUN
dti-1329	70	7	that	that	PRON
dti-1329	70	8	inhibit	inhibit	VERB
dti-1329	70	9	expression	expression	NOUN
dti-1329	70	10	of	of	ADP
dti-1329	70	11	nsr1	nsr1	PROPN
dti-1329	70	12	or	or	CCONJ
dti-1329	70	13	interfere	interfere	VERB
dti-1329	70	14	with	with	ADP
dti-1329	70	15	siderophore	siderophore	ADJ
dti-1329	70	16	pathways	pathway	NOUN
dti-1329	70	17	involving	involve	VERB
dti-1329	70	18	nsr1	nsr1	PROPN
dti-1329	70	19	could	could	AUX
dti-1329	70	20	conceivably	conceivably	ADV
dti-1329	70	21	suppress	suppress	VERB
dti-1329	70	22	bacterial	bacterial	ADJ
dti-1329	70	23	multiplication	multiplication	NOUN
dti-1329	70	24	by	by	ADP
dti-1329	70	25	blocking	block	VERB
dti-1329	70	26	iron	iron	NOUN
dti-1329	70	27	metabolism	metabolism	NOUN
dti-1329	70	28	.	.	PUNCT
dti-1329	71	1	these	these	PRON
dti-1329	71	2	and	and	CCONJ
dti-1329	71	3	other	other	ADJ
dti-1329	71	4	strategies	strategy	NOUN
dti-1329	71	5	may	may	AUX
dti-1329	71	6	provide	provide	VERB
dti-1329	71	7	a	a	DET
dti-1329	71	8	basis	basis	NOUN
dti-1329	71	9	for	for	ADP
dti-1329	71	10	therapeutic	therapeutic	ADJ
dti-1329	71	11	intervention	intervention	NOUN
dti-1329	71	12	for	for	ADP
dti-1329	71	13	the	the	DET
dti-1329	71	14	control	control	NOUN
dti-1329	71	15	of	of	ADP
dti-1329	71	16	a.	a.	PROPN
dti-1329	71	17	hydrophila	hydrophila	PROPN
dti-1329	71	18	infection	infection	NOUN
dti-1329	71	19	.	.	PUNCT
dti-1329	72	1	conclusions	conclusion	NOUN
dti-1329	72	2	the	the	DET
dti-1329	72	3	iron	iron	NOUN
dti-1329	72	4	uptake	uptake	ADJ
dti-1329	72	5	strategy	strategy	NOUN
dti-1329	72	6	of	of	ADP
dti-1329	72	7	a.	a.	NOUN
dti-1329	72	8	hydrophila	hydrophila	PROPN
dti-1329	72	9	has	have	AUX
dti-1329	72	10	previously	previously	ADV
dti-1329	72	11	been	be	AUX
dti-1329	72	12	described	describe	VERB
dti-1329	72	13	as	as	ADP
dti-1329	72	14	a	a	DET
dti-1329	72	15	ligand	ligand	ADJ
dti-1329	72	16	exchange	exchange	NOUN
dti-1329	72	17	mechanism	mechanism	NOUN
dti-1329	72	18	utilizing	utilize	VERB
dti-1329	72	19	a	a	DET
dti-1329	72	20	single	single	ADJ
dti-1329	72	21	nonspecific	nonspecific	ADJ
dti-1329	72	22	siderophore	siderophore	NOUN
dti-1329	72	23	receptor	receptor	NOUN
dti-1329	72	24	(	(	PUNCT
dti-1329	72	25	stintzi	stintzi	VERB
dti-1329	72	26	et	et	PROPN
dti-1329	72	27	al	al	PROPN
dti-1329	72	28	.	.	PROPN
dti-1329	72	29	2000	2000	NUM
dti-1329	72	30	)	)	PUNCT
dti-1329	72	31	.	.	PUNCT
dti-1329	73	1	here	here	ADV
dti-1329	73	2	we	we	PRON
dti-1329	73	3	report	report	VERB
dti-1329	73	4	the	the	DET
dti-1329	73	5	identifi	identifi	PROPN
dti-1329	73	6	cation	cation	NOUN
dti-1329	73	7	of	of	ADP
dti-1329	73	8	a	a	DET
dti-1329	73	9	novel	novel	ADJ
dti-1329	73	10	gene	gene	NOUN
dti-1329	73	11	from	from	ADP
dti-1329	73	12	a.	a.	NOUN
dti-1329	73	13	hydrophila	hydrophila	PROPN
dti-1329	73	14	potentially	potentially	ADV
dti-1329	73	15	encoding	encode	VERB
dti-1329	73	16	the	the	DET
dti-1329	73	17	abovementioned	abovementione	VERB
dti-1329	73	18	ligand	ligand	NOUN
dti-1329	73	19	exchange	exchange	NOUN
dti-1329	73	20	siderophore	siderophore	ADV
dti-1329	73	21	receptor	receptor	NOUN
dti-1329	73	22	.	.	PUNCT
dti-1329	74	1	the	the	DET
dti-1329	74	2	putative	putative	ADJ
dti-1329	74	3	protein	protein	NOUN
dti-1329	74	4	product	product	NOUN
dti-1329	74	5	of	of	ADP
dti-1329	74	6	nsr1	nsr1	PROPN
dti-1329	74	7	bears	bear	VERB
dti-1329	74	8	high	high	ADJ
dti-1329	74	9	amino	amino	NOUN
dti-1329	74	10	acid	acid	NOUN
dti-1329	74	11	sequence	sequence	NOUN
dti-1329	74	12	identity	identity	NOUN
dti-1329	74	13	and	and	CCONJ
dti-1329	74	14	similarity	similarity	NOUN
dti-1329	74	15	to	to	ADP
dti-1329	74	16	several	several	ADJ
dti-1329	74	17	known	know	VERB
dti-1329	74	18	siderophore	siderophore	ADJ
dti-1329	74	19	receptors	receptor	NOUN
dti-1329	74	20	.	.	PUNCT
dti-1329	75	1	in	in	ADP
dti-1329	75	2	addition	addition	NOUN
dti-1329	75	3	,	,	PUNCT
dti-1329	75	4	the	the	DET
dti-1329	75	5	predicted	predict	VERB
dti-1329	75	6	secondary	secondary	ADJ
dti-1329	75	7	structure	structure	NOUN
dti-1329	75	8	of	of	ADP
dti-1329	75	9	the	the	DET
dti-1329	75	10	protein	protein	NOUN
dti-1329	75	11	features	feature	VERB
dti-1329	75	12	two	two	NUM
dti-1329	75	13	distinct	distinct	ADJ
dti-1329	75	14	functional	functional	ADJ
dti-1329	75	15	domains	domain	NOUN
dti-1329	75	16	that	that	PRON
dti-1329	75	17	are	be	AUX
dti-1329	75	18	thought	think	VERB
dti-1329	75	19	to	to	PART
dti-1329	75	20	be	be	AUX
dti-1329	75	21	common	common	ADJ
dti-1329	75	22	to	to	ADP
dti-1329	75	23	all	all	DET
dti-1329	75	24	ferric	ferric	ADJ
dti-1329	75	25	-	-	PUNCT
dti-1329	75	26	siderophore	siderophore	NOUN
dti-1329	75	27	receptors	receptor	NOUN
dti-1329	75	28	(	(	PUNCT
dti-1329	75	29	stintzi	stintzi	VERB
dti-1329	75	30	et	et	PROPN
dti-1329	75	31	al	al	PROPN
dti-1329	75	32	.	.	PROPN
dti-1329	75	33	2000	2000	NUM
dti-1329	75	34	)	)	PUNCT
dti-1329	75	35	.	.	PUNCT
dti-1329	76	1	thus	thus	ADV
dti-1329	76	2	nsr1	nsr1	PROPN
dti-1329	76	3	likely	likely	ADV
dti-1329	76	4	encodes	encode	VERB
dti-1329	76	5	a	a	DET
dti-1329	76	6	receptor	receptor	NOUN
dti-1329	76	7	protein	protein	NOUN
dti-1329	76	8	involved	involve	VERB
dti-1329	76	9	in	in	ADP
dti-1329	76	10	siderophoremediated	siderophoremediate	VERB
dti-1329	76	11	iron	iron	NOUN
dti-1329	76	12	transport	transport	NOUN
dti-1329	76	13	.	.	PUNCT
dti-1329	77	1	as	as	SCONJ
dti-1329	77	2	a.	a.	NOUN
dti-1329	77	3	hydrophila	hydrophila	PROPN
dti-1329	77	4	has	have	AUX
dti-1329	77	5	been	be	AUX
dti-1329	77	6	shown	show	VERB
dti-1329	77	7	to	to	PART
dti-1329	77	8	exclusively	exclusively	ADV
dti-1329	77	9	utilize	utilize	VERB
dti-1329	77	10	a	a	DET
dti-1329	77	11	single	single	ADJ
dti-1329	77	12	ferricsiderophore	ferricsiderophore	ADJ
dti-1329	77	13	receptor	receptor	NOUN
dti-1329	77	14	for	for	ADP
dti-1329	77	15	iron	iron	NOUN
dti-1329	77	16	transport	transport	NOUN
dti-1329	77	17	,	,	PUNCT
dti-1329	77	18	the	the	DET
dti-1329	77	19	gene	gene	NOUN
dti-1329	77	20	product	product	NOUN
dti-1329	77	21	of	of	ADP
dti-1329	77	22	nsr1	nsr1	PROPN
dti-1329	77	23	is	be	AUX
dti-1329	77	24	an	an	DET
dti-1329	77	25	excellent	excellent	ADJ
dti-1329	77	26	candidate	candidate	NOUN
dti-1329	77	27	for	for	ADP
dti-1329	77	28	the	the	DET
dti-1329	77	29	receptor	receptor	NOUN
dti-1329	77	30	.	.	PUNCT
dti-1329	78	1	further	further	ADJ
dti-1329	78	2	investigation	investigation	NOUN
dti-1329	78	3	and	and	CCONJ
dti-1329	78	4	molecular	molecular	ADJ
dti-1329	78	5	characterization	characterization	NOUN
dti-1329	78	6	of	of	ADP
dti-1329	78	7	the	the	DET
dti-1329	78	8	protein	protein	NOUN
dti-1329	78	9	product	product	NOUN
dti-1329	78	10	of	of	ADP
dti-1329	78	11	nsr1	nsr1	PROPN
dti-1329	78	12	may	may	AUX
dti-1329	78	13	figure	figure	VERB
dti-1329	78	14	3	3	NUM
dti-1329	78	15	.	.	PUNCT
dti-1329	78	16	amino	amino	NOUN
dti-1329	78	17	acid	acid	NOUN
dti-1329	78	18	sequence	sequence	NOUN
dti-1329	78	19	alignment	alignment	NOUN
dti-1329	78	20	of	of	ADP
dti-1329	78	21	the	the	DET
dti-1329	78	22	putative	putative	ADJ
dti-1329	78	23	a.	a.	NOUN
dti-1329	78	24	hydrophila	hydrophila	NOUN
dti-1329	79	1	siderophore	siderophore	ADV
dti-1329	79	2	receptor	receptor	NOUN
dti-1329	79	3	(	(	PUNCT
dti-1329	79	4	here	here	ADV
dti-1329	79	5	denoted	denote	VERB
dti-1329	79	6	ahyd	ahyd	NOUN
dti-1329	79	7	)	)	PUNCT
dti-1329	79	8	with	with	ADP
dti-1329	79	9	known	know	VERB
dti-1329	79	10	ferric	ferric	ADJ
dti-1329	79	11	-	-	PUNCT
dti-1329	79	12	siderophore	siderophore	NOUN
dti-1329	79	13	receptors	receptor	NOUN
dti-1329	79	14	from	from	ADP
dti-1329	79	15	various	various	ADJ
dti-1329	79	16	bacteria	bacteria	NOUN
dti-1329	79	17	:	:	PUNCT
dti-1329	79	18	vpar	vpar	NOUN
dti-1329	79	19	,	,	PUNCT
dti-1329	79	20	vibrio	vibrio	ADJ
dti-1329	79	21	parahaemolyticus	parahaemolyticus	NOUN
dti-1329	79	22	ferrichrome	ferrichrome	VERB
dti-1329	79	23	receptor	receptor	NOUN
dti-1329	79	24	fhua	fhua	NOUN
dti-1329	79	25	(	(	PUNCT
dti-1329	79	26	genbank	genbank	PROPN
dti-1329	79	27	bad06905	bad06905	PROPN
dti-1329	79	28	)	)	PUNCT
dti-1329	79	29	;	;	PUNCT
dti-1329	79	30	csal	csal	NOUN
dti-1329	79	31	,	,	PUNCT
dti-1329	79	32	chromohalobacter	chromohalobacter	NOUN
dti-1329	79	33	salexigens	salexigen	NOUN
dti-1329	79	34	tonb	tonb	ADJ
dti-1329	79	35	-	-	PUNCT
dti-1329	79	36	dependent	dependent	ADJ
dti-1329	79	37	siderophore	siderophore	ADJ
dti-1329	79	38	receptor	receptor	NOUN
dti-1329	79	39	(	(	PUNCT
dti-1329	79	40	genbank	genbank	PROPN
dti-1329	79	41	yp_573101	yp_573101	PROPN
dti-1329	79	42	)	)	PUNCT
dti-1329	79	43	;	;	PUNCT
dti-1329	79	44	and	and	CCONJ
dti-1329	79	45	aple	aple	NOUN
dti-1329	79	46	,	,	PUNCT
dti-1329	79	47	actinobacillus	actinobacillus	ADJ
dti-1329	79	48	pleuropneumoniae	pleuropneumoniae	ADJ
dti-1329	79	49	ferric	ferric	ADJ
dti-1329	79	50	hydroxamate	hydroxamate	NOUN
dti-1329	79	51	receptor	receptor	NOUN
dti-1329	79	52	fhua	fhua	NOUN
dti-1329	79	53	(	(	PUNCT
dti-1329	79	54	genbank	genbank	PROPN
dti-1329	79	55	dq249800	dq249800	PROPN
dti-1329	79	56	)	)	PUNCT
dti-1329	79	57	.	.	PUNCT
dti-1329	80	1	single	single	ADJ
dti-1329	80	2	fully	fully	ADV
dti-1329	80	3	conserved	conserve	VERB
dti-1329	80	4	residues	residue	NOUN
dti-1329	80	5	(	(	PUNCT
dti-1329	80	6	*	*	PUNCT
dti-1329	80	7	)	)	PUNCT
dti-1329	80	8	are	be	AUX
dti-1329	80	9	highlighted	highlight	VERB
dti-1329	80	10	,	,	PUNCT
dti-1329	80	11	and	and	CCONJ
dti-1329	80	12	strong	strong	ADJ
dti-1329	80	13	conserved	conserved	ADJ
dti-1329	80	14	groups	group	NOUN
dti-1329	80	15	(	(	PUNCT
dti-1329	80	16	:)	:)	INTJ
dti-1329	80	17	and	and	CCONJ
dti-1329	80	18	weak	weak	ADJ
dti-1329	80	19	conserved	conserved	ADJ
dti-1329	80	20	groups	group	NOUN
dti-1329	80	21	(	(	PUNCT
dti-1329	80	22	.	.	PUNCT
dti-1329	80	23	)	)	PUNCT
dti-1329	80	24	are	be	AUX
dti-1329	80	25	indicated	indicate	VERB
dti-1329	80	26	.	.	PUNCT
dti-1329	81	1	36	36	NUM
dti-1329	81	2	tsen	tsen	ADJ
dti-1329	81	3	drug	drug	NOUN
dti-1329	81	4	target	target	NOUN
dti-1329	81	5	insights	insight	NOUN
dti-1329	81	6	2008:3	2008:3	NUM
dti-1329	81	7	contribute	contribute	VERB
dti-1329	81	8	to	to	ADP
dti-1329	81	9	the	the	DET
dti-1329	81	10	elucidation	elucidation	NOUN
dti-1329	81	11	of	of	ADP
dti-1329	81	12	the	the	DET
dti-1329	81	13	iron	iron	NOUN
dti-1329	81	14	uptake	uptake	ADJ
dti-1329	81	15	mechanism	mechanism	NOUN
dti-1329	81	16	of	of	ADP
dti-1329	81	17	a.	a.	NOUN
dti-1329	81	18	hydrophila	hydrophila	PROPN
dti-1329	81	19	and	and	CCONJ
dti-1329	81	20	may	may	AUX
dti-1329	81	21	lead	lead	VERB
dti-1329	81	22	to	to	ADP
dti-1329	81	23	the	the	DET
dti-1329	81	24	development	development	NOUN
dti-1329	81	25	of	of	ADP
dti-1329	81	26	new	new	ADJ
dti-1329	81	27	antibiotics	antibiotic	NOUN
dti-1329	81	28	targeting	target	VERB
dti-1329	81	29	either	either	CCONJ
dti-1329	81	30	nsr1	nsr1	PROPN
dti-1329	81	31	or	or	CCONJ
dti-1329	81	32	its	its	PRON
dti-1329	81	33	product	product	NOUN
dti-1329	81	34	for	for	ADP
dti-1329	81	35	use	use	NOUN
dti-1329	81	36	in	in	ADP
dti-1329	81	37	controlling	control	VERB
dti-1329	81	38	a.	a.	NOUN
dti-1329	81	39	hydrophila	hydrophila	PROPN
dti-1329	81	40	infection	infection	NOUN
dti-1329	81	41	.	.	PUNCT
dti-1329	82	1	acknowledgements	acknowledgement	NOUN
dti-1329	82	2	the	the	DET
dti-1329	82	3	author	author	NOUN
dti-1329	82	4	would	would	AUX
dti-1329	82	5	like	like	VERB
dti-1329	82	6	to	to	PART
dti-1329	82	7	thank	thank	VERB
dti-1329	82	8	nicholas	nicholas	PROPN
dti-1329	82	9	fitzkee	fitzkee	PROPN
dti-1329	82	10	for	for	ADP
dti-1329	82	11	his	his	PRON
dti-1329	82	12	important	important	ADJ
dti-1329	82	13	contributions	contribution	NOUN
dti-1329	82	14	to	to	ADP
dti-1329	82	15	the	the	DET
dti-1329	82	16	implementation	implementation	NOUN
dti-1329	82	17	of	of	ADP
dti-1329	82	18	the	the	DET
dti-1329	82	19	computer	computer	NOUN
dti-1329	82	20	programs	program	NOUN
dti-1329	82	21	used	use	VERB
dti-1329	82	22	in	in	ADP
dti-1329	82	23	this	this	DET
dti-1329	82	24	study	study	NOUN
dti-1329	82	25	and	and	CCONJ
dti-1329	82	26	for	for	ADP
dti-1329	82	27	his	his	PRON
dti-1329	82	28	helpful	helpful	ADJ
dti-1329	82	29	and	and	CCONJ
dti-1329	82	30	informative	informative	ADJ
dti-1329	82	31	discussions	discussion	NOUN
dti-1329	82	32	.	.	PUNCT
dti-1329	83	1	references	reference	NOUN
dti-1329	83	2	agger	agger	PROPN
dti-1329	83	3	,	,	PUNCT
dti-1329	83	4	w.a	w.a	PROPN
dti-1329	83	5	.	.	PROPN
dti-1329	83	6	,	,	PUNCT
dti-1329	83	7	mccormick	mccormick	PROPN
dti-1329	83	8	,	,	PUNCT
dti-1329	83	9	j.d	j.d	PROPN
dti-1329	83	10	.	.	PROPN
dti-1329	83	11	and	and	CCONJ
dti-1329	83	12	gurwith	gurwith	PROPN
dti-1329	83	13	,	,	PUNCT
dti-1329	83	14	m.j	m.j	PROPN
dti-1329	83	15	.	.	PROPN
dti-1329	83	16	1985	1985	NUM
dti-1329	83	17	.	.	PUNCT
dti-1329	84	1	clinical	clinical	ADJ
dti-1329	84	2	and	and	CCONJ
dti-1329	84	3	microbiological	microbiological	ADJ
dti-1329	84	4	features	feature	NOUN
dti-1329	84	5	of	of	ADP
dti-1329	84	6	aeromonas	aeromonas	PROPN
dti-1329	84	7	hydrophila	hydrophila	PROPN
dti-1329	84	8	-	-	PUNCT
dti-1329	84	9	associated	associate	VERB
dti-1329	84	10	diarrhea	diarrhea	NOUN
dti-1329	84	11	.	.	PUNCT
dti-1329	85	1	j.	j.	PROPN
dti-1329	85	2	clin	clin	PROPN
dti-1329	85	3	.	.	PUNCT
dti-1329	86	1	microbiol	microbiol	PROPN
dti-1329	86	2	.	.	PUNCT
dti-1329	86	3	,	,	PUNCT
dti-1329	87	1	21:909–13	21:909–13	PROPN
dti-1329	87	2	.	.	PROPN
dti-1329	87	3	apostol	apostol	PROPN
dti-1329	87	4	,	,	PUNCT
dti-1329	87	5	m.	m.	NOUN
dti-1329	87	6	,	,	PUNCT
dti-1329	87	7	baret	baret	PROPN
dti-1329	87	8	,	,	PUNCT
dti-1329	87	9	p.	p.	PROPN
dti-1329	87	10	,	,	PUNCT
dti-1329	87	11	serratrice	serratrice	PROPN
dti-1329	87	12	,	,	PUNCT
dti-1329	87	13	g.	g.	PROPN
dti-1329	87	14	,	,	PUNCT
dti-1329	87	15	desbrières	desbrière	NOUN
dti-1329	87	16	,	,	PUNCT
dti-1329	87	17	j.	j.	PROPN
dti-1329	87	18	,	,	PUNCT
dti-1329	87	19	putaux	putaux	PROPN
dti-1329	87	20	,	,	PUNCT
dti-1329	87	21	j.l	j.l	PROPN
dti-1329	87	22	.	.	PROPN
dti-1329	87	23	,	,	PUNCT
dti-1329	87	24	stèbè	stèbè	VERB
dti-1329	87	25	,	,	PUNCT
dti-1329	87	26	m.j	m.j	PROPN
dti-1329	87	27	.	.	PROPN
dti-1329	87	28	,	,	PUNCT
dti-1329	87	29	expert	expert	PROPN
dti-1329	87	30	,	,	PUNCT
dti-1329	87	31	d.	d.	PROPN
dti-1329	87	32	and	and	CCONJ
dti-1329	87	33	pierre	pierre	PROPN
dti-1329	87	34	,	,	PUNCT
dti-1329	87	35	j.l	j.l	PROPN
dti-1329	87	36	.	.	PROPN
dti-1329	87	37	2005	2005	NUM
dti-1329	87	38	.	.	PUNCT
dti-1329	88	1	self	self	NOUN
dti-1329	88	2	-	-	PUNCT
dti-1329	88	3	assembly	assembly	NOUN
dti-1329	88	4	of	of	ADP
dti-1329	88	5	an	an	DET
dti-1329	88	6	amphiphilic	amphiphilic	ADJ
dti-1329	88	7	iron(iii	iron(iii	NOUN
dti-1329	88	8	)	)	PUNCT
dti-1329	88	9	chelator	chelator	NOUN
dti-1329	88	10	:	:	PUNCT
dti-1329	88	11	mimicking	mimic	VERB
dti-1329	88	12	iron	iron	NOUN
dti-1329	88	13	acquisition	acquisition	NOUN
dti-1329	88	14	in	in	ADP
dti-1329	88	15	marine	marine	ADJ
dti-1329	88	16	bacteria	bacteria	NOUN
dti-1329	88	17	.	.	PUNCT
dti-1329	89	1	angew	angew	PROPN
dti-1329	89	2	.	.	PUNCT
dti-1329	90	1	chem	chem	PROPN
dti-1329	90	2	.	.	PUNCT
dti-1329	90	3	,	,	PUNCT
dti-1329	91	1	117:2636–8	117:2636–8	PROPN
dti-1329	91	2	.	.	PUNCT
dti-1329	91	3	bates	bates	PROPN
dti-1329	91	4	,	,	PUNCT
dti-1329	91	5	p.a	p.a	PROPN
dti-1329	91	6	.	.	PROPN
dti-1329	91	7	,	,	PUNCT
dti-1329	91	8	kelley	kelley	PROPN
dti-1329	91	9	,	,	PUNCT
dti-1329	91	10	l.a	l.a	PROPN
dti-1329	91	11	.	.	PROPN
dti-1329	91	12	,	,	PUNCT
dti-1329	91	13	maccallum	maccallum	PROPN
dti-1329	91	14	,	,	PUNCT
dti-1329	91	15	r.m	r.m	PROPN
dti-1329	91	16	.	.	PROPN
dti-1329	91	17	and	and	CCONJ
dti-1329	91	18	sternberg	sternberg	PROPN
dti-1329	91	19	,	,	PUNCT
dti-1329	91	20	m.j.e	m.j.e	PROPN
dti-1329	91	21	.	.	PUNCT
dti-1329	91	22	2001	2001	NUM
dti-1329	91	23	.	.	PUNCT
dti-1329	92	1	enhancement	enhancement	NOUN
dti-1329	92	2	of	of	ADP
dti-1329	92	3	protein	protein	NOUN
dti-1329	92	4	modeling	modeling	NOUN
dti-1329	92	5	by	by	ADP
dti-1329	92	6	human	human	ADJ
dti-1329	92	7	intervention	intervention	NOUN
dti-1329	92	8	in	in	ADP
dti-1329	92	9	applying	apply	VERB
dti-1329	92	10	the	the	DET
dti-1329	92	11	automatic	automatic	ADJ
dti-1329	92	12	programs	program	NOUN
dti-1329	92	13	3d	3d	NOUN
dti-1329	92	14	-	-	PUNCT
dti-1329	92	15	jigsaw	jigsaw	NOUN
dti-1329	92	16	and	and	CCONJ
dti-1329	92	17	3dpssm	3dpssm	NUM
dti-1329	92	18	.	.	PUNCT
dti-1329	92	19	proteins	protein	NOUN
dti-1329	92	20	:	:	PUNCT
dti-1329	92	21	structure	structure	NOUN
dti-1329	92	22	,	,	PUNCT
dti-1329	92	23	function	function	NOUN
dti-1329	92	24	and	and	CCONJ
dti-1329	92	25	genetics	genetic	NOUN
dti-1329	92	26	,	,	PUNCT
dti-1329	92	27	(	(	PUNCT
dti-1329	92	28	suppl	suppl	ADJ
dti-1329	92	29	5):39–46	5):39–46	NUM
dti-1329	92	30	.	.	PUNCT
dti-1329	93	1	bates	bate	NOUN
dti-1329	93	2	,	,	PUNCT
dti-1329	93	3	p.a	p.a	PROPN
dti-1329	93	4	.	.	PROPN
dti-1329	93	5	and	and	CCONJ
dti-1329	93	6	sternberg	sternberg	PROPN
dti-1329	93	7	,	,	PUNCT
dti-1329	93	8	m.j.e	m.j.e	PROPN
dti-1329	93	9	.	.	PUNCT
dti-1329	93	10	1999	1999	NUM
dti-1329	93	11	.	.	PUNCT
dti-1329	94	1	model	model	NOUN
dti-1329	94	2	building	building	NOUN
dti-1329	94	3	by	by	ADP
dti-1329	94	4	comparison	comparison	NOUN
dti-1329	94	5	at	at	ADP
dti-1329	94	6	casp3	casp3	NOUN
dti-1329	94	7	:	:	PUNCT
dti-1329	94	8	using	use	VERB
dti-1329	94	9	expert	expert	ADJ
dti-1329	94	10	knowledge	knowledge	NOUN
dti-1329	94	11	and	and	CCONJ
dti-1329	94	12	computer	computer	NOUN
dti-1329	94	13	automation	automation	NOUN
dti-1329	94	14	.	.	PUNCT
dti-1329	95	1	proteins	protein	NOUN
dti-1329	95	2	:	:	PUNCT
dti-1329	95	3	structure	structure	NOUN
dti-1329	95	4	,	,	PUNCT
dti-1329	95	5	function	function	NOUN
dti-1329	95	6	and	and	CCONJ
dti-1329	95	7	genetics	genetic	NOUN
dti-1329	95	8	,	,	PUNCT
dti-1329	95	9	(	(	PUNCT
dti-1329	95	10	suppl	suppl	ADJ
dti-1329	95	11	3):47–54	3):47–54	PROPN
dti-1329	95	12	.	.	PUNCT
dti-1329	96	1	beddek	beddek	PROPN
dti-1329	96	2	,	,	PUNCT
dti-1329	96	3	a.j	a.j	PROPN
dti-1329	96	4	.	.	PROPN
dti-1329	96	5	,	,	PUNCT
dti-1329	96	6	sheehan	sheehan	PROPN
dti-1329	96	7	,	,	PUNCT
dti-1329	96	8	b.j	b.j	PROPN
dti-1329	96	9	.	.	PROPN
dti-1329	96	10	,	,	PUNCT
dti-1329	96	11	bossé	bossé	NOUN
dti-1329	96	12	,	,	PUNCT
dti-1329	96	13	j.t	j.t	PROPN
dti-1329	96	14	.	.	PROPN
dti-1329	96	15	,	,	PUNCT
dti-1329	96	16	rycroft	rycroft	PROPN
dti-1329	96	17	,	,	PUNCT
dti-1329	96	18	a.n	a.n	PROPN
dti-1329	96	19	.	.	PROPN
dti-1329	96	20	,	,	PUNCT
dti-1329	96	21	kroll	kroll	PROPN
dti-1329	96	22	,	,	PUNCT
dti-1329	96	23	j.s	j.s	PROPN
dti-1329	96	24	.	.	PROPN
dti-1329	96	25	and	and	CCONJ
dti-1329	96	26	langford	langford	PROPN
dti-1329	96	27	,	,	PUNCT
dti-1329	96	28	p.r	p.r	PROPN
dti-1329	96	29	.	.	PROPN
dti-1329	96	30	2004	2004	NUM
dti-1329	96	31	.	.	PUNCT
dti-1329	97	1	two	two	NUM
dti-1329	97	2	tonb	tonb	ADJ
dti-1329	97	3	systems	system	NOUN
dti-1329	97	4	in	in	ADP
dti-1329	97	5	actinobacillus	actinobacillus	ADJ
dti-1329	97	6	pleuropneumoniae	pleuropneumoniae	NOUN
dti-1329	97	7	:	:	PUNCT
dti-1329	97	8	their	their	PRON
dti-1329	97	9	roles	role	NOUN
dti-1329	97	10	in	in	ADP
dti-1329	97	11	iron	iron	NOUN
dti-1329	97	12	acquisition	acquisition	NOUN
dti-1329	97	13	and	and	CCONJ
dti-1329	97	14	virulence	virulence	NOUN
dti-1329	97	15	.	.	PUNCT
dti-1329	98	1	infect	infect	VERB
dti-1329	98	2	.	.	PUNCT
dti-1329	99	1	immun	immun	PROPN
dti-1329	99	2	.	.	PROPN
dti-1329	99	3	,	,	PUNCT
dti-1329	99	4	72:701–8	72:701–8	NUM
dti-1329	99	5	.	.	PUNCT
dti-1329	99	6	contreras	contreras	PROPN
dti-1329	99	7	-	-	PUNCT
dti-1329	99	8	moreira	moreira	PROPN
dti-1329	99	9	,	,	PUNCT
dti-1329	99	10	b.	b.	PROPN
dti-1329	99	11	and	and	CCONJ
dti-1329	99	12	bates	bates	PROPN
dti-1329	99	13	,	,	PUNCT
dti-1329	99	14	p.a	p.a	PROPN
dti-1329	99	15	.	.	PROPN
dti-1329	99	16	2002	2002	NUM
dti-1329	99	17	.	.	PUNCT
dti-1329	100	1	domain	domain	NOUN
dti-1329	100	2	fi	fi	NOUN
dti-1329	100	3	shing	shing	PROPN
dti-1329	100	4	:	:	PUNCT
dti-1329	100	5	a	a	DET
dti-1329	100	6	fi	fi	NOUN
dti-1329	100	7	rst	rst	ADJ
dti-1329	100	8	step	step	NOUN
dti-1329	100	9	in	in	ADP
dti-1329	100	10	protein	protein	NOUN
dti-1329	100	11	comparative	comparative	ADJ
dti-1329	100	12	modeling	modeling	NOUN
dti-1329	100	13	.	.	PUNCT
dti-1329	101	1	bioinformatics	bioinformatic	NOUN
dti-1329	101	2	,	,	PUNCT
dti-1329	101	3	18:1141–2	18:1141–2	NUM
dti-1329	101	4	.	.	PUNCT
dti-1329	102	1	coulton	coulton	PROPN
dti-1329	102	2	,	,	PUNCT
dti-1329	102	3	j.w	j.w	PROPN
dti-1329	102	4	.	.	PROPN
dti-1329	102	5	,	,	PUNCT
dti-1329	102	6	mason	mason	PROPN
dti-1329	102	7	,	,	PUNCT
dti-1329	102	8	p.	p.	PROPN
dti-1329	102	9	,	,	PUNCT
dti-1329	102	10	cameron	cameron	PROPN
dti-1329	102	11	,	,	PUNCT
dti-1329	102	12	d.r	d.r	PROPN
dti-1329	102	13	.	.	PROPN
dti-1329	102	14	,	,	PUNCT
dti-1329	102	15	carmel	carmel	PROPN
dti-1329	102	16	,	,	PUNCT
dti-1329	102	17	g.	g.	PROPN
dti-1329	102	18	,	,	PUNCT
dti-1329	102	19	jean	jean	PROPN
dti-1329	102	20	,	,	PUNCT
dti-1329	102	21	r.	r.	PROPN
dti-1329	102	22	and	and	CCONJ
dti-1329	102	23	rode	ride	VERB
dti-1329	102	24	,	,	PUNCT
dti-1329	102	25	h.n	h.n	PROPN
dti-1329	102	26	.	.	PROPN
dti-1329	102	27	1986	1986	NUM
dti-1329	102	28	.	.	PUNCT
dti-1329	103	1	protein	protein	NOUN
dti-1329	103	2	fusions	fusion	NOUN
dti-1329	103	3	of	of	ADP
dti-1329	103	4	β	β	NOUN
dti-1329	103	5	-	-	NOUN
dti-1329	103	6	galactosidase	galactosidase	NOUN
dti-1329	103	7	to	to	ADP
dti-1329	103	8	the	the	DET
dti-1329	103	9	ferrichrome	ferrichrome	NOUN
dti-1329	103	10	-	-	PUNCT
dti-1329	103	11	iron	iron	NOUN
dti-1329	103	12	receptor	receptor	NOUN
dti-1329	103	13	of	of	ADP
dti-1329	103	14	escherichia	escherichia	NOUN
dti-1329	103	15	coli	coli	NOUN
dti-1329	103	16	.	.	PUNCT
dti-1329	104	1	j.	j.	PROPN
dti-1329	104	2	bacteriol	bacteriol	PROPN
dti-1329	104	3	.	.	PUNCT
dti-1329	104	4	,	,	PUNCT
dti-1329	104	5	165:181–92	165:181–92	NUM
dti-1329	104	6	.	.	PUNCT
dti-1329	105	1	janda	janda	PROPN
dti-1329	105	2	,	,	PUNCT
dti-1329	105	3	j.m	j.m	PROPN
dti-1329	105	4	.	.	PROPN
dti-1329	105	5	and	and	CCONJ
dti-1329	105	6	abbott	abbott	PROPN
dti-1329	105	7	,	,	PUNCT
dti-1329	105	8	s.l	s.l	PROPN
dti-1329	105	9	.	.	PROPN
dti-1329	105	10	1998	1998	NUM
dti-1329	105	11	.	.	PUNCT
dti-1329	106	1	evolving	evolve	VERB
dti-1329	106	2	concepts	concept	NOUN
dti-1329	106	3	regarding	regard	VERB
dti-1329	106	4	the	the	DET
dti-1329	106	5	genus	genus	NOUN
dti-1329	106	6	aeromonas	aeromona	NOUN
dti-1329	106	7	:	:	PUNCT
dti-1329	106	8	an	an	DET
dti-1329	106	9	expanding	expand	VERB
dti-1329	106	10	panorama	panorama	NOUN
dti-1329	106	11	of	of	ADP
dti-1329	106	12	species	specie	NOUN
dti-1329	106	13	,	,	PUNCT
dti-1329	106	14	disease	disease	NOUN
dti-1329	106	15	presentations	presentation	NOUN
dti-1329	106	16	,	,	PUNCT
dti-1329	106	17	and	and	CCONJ
dti-1329	106	18	unanswered	unanswered	ADJ
dti-1329	106	19	questions	question	NOUN
dti-1329	106	20	.	.	PUNCT
dti-1329	107	1	clin	clin	PROPN
dti-1329	107	2	.	.	PUNCT
dti-1329	108	1	infect	infect	VERB
dti-1329	108	2	.	.	PUNCT
dti-1329	109	1	dis	dis	PROPN
dti-1329	109	2	.	.	PROPN
dti-1329	109	3	,	,	PUNCT
dti-1329	109	4	2:332–44	2:332–44	X
dti-1329	109	5	.	.	PUNCT
dti-1329	109	6	kyte	kyte	PROPN
dti-1329	109	7	,	,	PUNCT
dti-1329	109	8	j.	j.	PROPN
dti-1329	109	9	and	and	CCONJ
dti-1329	109	10	doolittle	doolittle	PROPN
dti-1329	109	11	,	,	PUNCT
dti-1329	109	12	r.f	r.f	PROPN
dti-1329	109	13	.	.	PROPN
dti-1329	109	14	1982	1982	NUM
dti-1329	109	15	.	.	PUNCT
dti-1329	110	1	a	a	DET
dti-1329	110	2	simple	simple	ADJ
dti-1329	110	3	method	method	NOUN
dti-1329	110	4	for	for	ADP
dti-1329	110	5	displaying	display	VERB
dti-1329	110	6	the	the	DET
dti-1329	110	7	hydropathic	hydropathic	ADJ
dti-1329	110	8	character	character	NOUN
dti-1329	110	9	of	of	ADP
dti-1329	110	10	a	a	DET
dti-1329	110	11	protein	protein	NOUN
dti-1329	110	12	.	.	PUNCT
dti-1329	111	1	j.	j.	PROPN
dti-1329	111	2	mol	mol	PROPN
dti-1329	111	3	.	.	PUNCT
dti-1329	112	1	biol	biol	PROPN
dti-1329	112	2	.	.	PUNCT
dti-1329	112	3	,	,	PUNCT
dti-1329	113	1	157:105–32	157:105–32	NUM
dti-1329	113	2	.	.	PUNCT
dti-1329	114	1	miethke	miethke	PROPN
dti-1329	114	2	,	,	PUNCT
dti-1329	114	3	m.	m.	NOUN
dti-1329	114	4	and	and	CCONJ
dti-1329	114	5	marahiel	marahiel	PROPN
dti-1329	114	6	,	,	PUNCT
dti-1329	114	7	m.a	m.a	PROPN
dti-1329	114	8	.	.	PROPN
dti-1329	114	9	2007	2007	NUM
dti-1329	114	10	.	.	PUNCT
dti-1329	115	1	siderophore	siderophore	ADV
dti-1329	115	2	-	-	PUNCT
dti-1329	115	3	based	base	VERB
dti-1329	115	4	iron	iron	NOUN
dti-1329	115	5	acquisition	acquisition	NOUN
dti-1329	115	6	and	and	CCONJ
dti-1329	115	7	pathogen	pathogen	NOUN
dti-1329	115	8	control	control	NOUN
dti-1329	115	9	.	.	PUNCT
dti-1329	116	1	microbiol	microbiol	PROPN
dti-1329	116	2	.	.	PUNCT
dti-1329	117	1	mol	mol	PROPN
dti-1329	117	2	.	.	PUNCT
dti-1329	118	1	biol	biol	PROPN
dti-1329	118	2	.	.	PUNCT
dti-1329	119	1	rev	rev	PROPN
dti-1329	119	2	.	.	PROPN
dti-1329	119	3	,	,	PUNCT
dti-1329	119	4	71:413–51	71:413–51	NUM
dti-1329	119	5	.	.	PUNCT
dti-1329	120	1	mikael	mikael	PROPN
dti-1329	120	2	,	,	PUNCT
dti-1329	120	3	l.g	l.g	PROPN
dti-1329	120	4	.	.	PROPN
dti-1329	120	5	,	,	PUNCT
dti-1329	120	6	srikumar	srikumar	PROPN
dti-1329	120	7	,	,	PUNCT
dti-1329	120	8	r.	r.	PROPN
dti-1329	120	9	,	,	PUNCT
dti-1329	120	10	coulton	coulton	PROPN
dti-1329	120	11	,	,	PUNCT
dti-1329	120	12	j.w	j.w	PROPN
dti-1329	120	13	.	.	PROPN
dti-1329	120	14	and	and	CCONJ
dti-1329	120	15	jacques	jacques	PROPN
dti-1329	120	16	,	,	PUNCT
dti-1329	120	17	m.	m.	NOUN
dti-1329	120	18	2003	2003	NUM
dti-1329	120	19	.	.	PUNCT
dti-1329	121	1	fhua	fhua	NOUN
dti-1329	121	2	of	of	ADP
dti-1329	121	3	actinobacillus	actinobacillus	ADJ
dti-1329	121	4	pleuropneumoniae	pleuropneumoniae	NOUN
dti-1329	121	5	encodes	encode	VERB
dti-1329	121	6	a	a	DET
dti-1329	121	7	ferrichrome	ferrichrome	NOUN
dti-1329	121	8	receptor	receptor	NOUN
dti-1329	121	9	but	but	CCONJ
dti-1329	121	10	is	be	AUX
dti-1329	121	11	not	not	PART
dti-1329	121	12	regulated	regulate	VERB
dti-1329	121	13	by	by	ADP
dti-1329	121	14	iron	iron	NOUN
dti-1329	121	15	.	.	PUNCT
dti-1329	122	1	infect	infect	VERB
dti-1329	122	2	.	.	PUNCT
dti-1329	123	1	immun	immun	PROPN
dti-1329	123	2	.	.	PROPN
dti-1329	123	3	,	,	PUNCT
dti-1329	123	4	71:2911–5	71:2911–5	NUM
dti-1329	123	5	.	.	PUNCT
dti-1329	124	1	newton	newton	PROPN
dti-1329	124	2	,	,	PUNCT
dti-1329	124	3	s.m.c	s.m.c	PROPN
dti-1329	124	4	.	.	PROPN
dti-1329	124	5	,	,	PUNCT
dti-1329	124	6	allen	allen	PROPN
dti-1329	124	7	,	,	PUNCT
dti-1329	124	8	j.s	j.s	PROPN
dti-1329	124	9	.	.	PROPN
dti-1329	124	10	,	,	PUNCT
dti-1329	124	11	cao	cao	PROPN
dti-1329	124	12	,	,	PUNCT
dti-1329	124	13	z.	z.	PROPN
dti-1329	124	14	,	,	PUNCT
dti-1329	124	15	qi	qi	PROPN
dti-1329	124	16	,	,	PUNCT
dti-1329	124	17	z.	z.	PROPN
dti-1329	124	18	,	,	PUNCT
dti-1329	124	19	jian	jian	PROPN
dti-1329	124	20	,	,	PUNCT
dti-1329	124	21	x.	x.	PROPN
dti-1329	124	22	,	,	PUNCT
dti-1329	124	23	sprencel	sprencel	PROPN
dti-1329	124	24	,	,	PUNCT
dti-1329	124	25	c.	c.	PROPN
dti-1329	124	26	,	,	PUNCT
dti-1329	124	27	igo	igo	PROPN
dti-1329	124	28	,	,	PUNCT
dti-1329	124	29	j.d	j.d	PROPN
dti-1329	124	30	.	.	PROPN
dti-1329	124	31	,	,	PUNCT
dti-1329	124	32	foster	foster	PROPN
dti-1329	124	33	,	,	PUNCT
dti-1329	124	34	s.b	s.b	PROPN
dti-1329	124	35	.	.	PROPN
dti-1329	124	36	,	,	PUNCT
dti-1329	124	37	payne	payne	PROPN
dti-1329	124	38	,	,	PUNCT
dti-1329	124	39	m.a	m.a	PROPN
dti-1329	124	40	.	.	PROPN
dti-1329	124	41	and	and	CCONJ
dti-1329	124	42	klebba	klebba	PROPN
dti-1329	124	43	,	,	PUNCT
dti-1329	124	44	p.e	p.e	PROPN
dti-1329	124	45	.	.	PROPN
dti-1329	124	46	1997	1997	NUM
dti-1329	124	47	.	.	PUNCT
dti-1329	125	1	double	double	ADJ
dti-1329	125	2	mutagenesis	mutagenesis	NOUN
dti-1329	125	3	of	of	ADP
dti-1329	125	4	a	a	DET
dti-1329	125	5	positive	positive	ADJ
dti-1329	125	6	charge	charge	NOUN
dti-1329	125	7	cluster	cluster	NOUN
dti-1329	125	8	in	in	ADP
dti-1329	125	9	the	the	DET
dti-1329	125	10	ligand	ligand	ADJ
dti-1329	125	11	binding	bind	VERB
dti-1329	125	12	site	site	NOUN
dti-1329	125	13	of	of	ADP
dti-1329	125	14	the	the	DET
dti-1329	125	15	ferric	ferric	ADJ
dti-1329	125	16	enterobactin	enterobactin	NOUN
dti-1329	125	17	receptor	receptor	NOUN
dti-1329	125	18	,	,	PUNCT
dti-1329	125	19	fepa	fepa	NOUN
dti-1329	125	20	.	.	PUNCT
dti-1329	126	1	proc	proc	PROPN
dti-1329	126	2	.	.	PUNCT
dti-1329	127	1	natl	natl	PROPN
dti-1329	127	2	.	.	PUNCT
dti-1329	128	1	acad	acad	PROPN
dti-1329	128	2	.	.	PUNCT
dti-1329	129	1	sci	sci	PROPN
dti-1329	129	2	.	.	PROPN
dti-1329	129	3	,	,	PUNCT
dti-1329	129	4	94:4560–5	94:4560–5	X
dti-1329	129	5	.	.	PUNCT
dti-1329	130	1	payne	payne	PROPN
dti-1329	130	2	,	,	PUNCT
dti-1329	130	3	s.m	s.m	PROPN
dti-1329	130	4	.	.	PROPN
dti-1329	130	5	and	and	CCONJ
dti-1329	130	6	finkelstein	finkelstein	PROPN
dti-1329	130	7	,	,	PUNCT
dti-1329	130	8	r.a	r.a	PROPN
dti-1329	130	9	.	.	PROPN
dti-1329	130	10	1978	1978	NUM
dti-1329	130	11	.	.	PUNCT
dti-1329	131	1	the	the	DET
dti-1329	131	2	critical	critical	ADJ
dti-1329	131	3	role	role	NOUN
dti-1329	131	4	of	of	ADP
dti-1329	131	5	iron	iron	NOUN
dti-1329	131	6	in	in	ADP
dti-1329	131	7	hostbacterial	hostbacterial	ADJ
dti-1329	131	8	interactions	interaction	NOUN
dti-1329	131	9	.	.	PUNCT
dti-1329	132	1	j.	j.	PROPN
dti-1329	132	2	clin	clin	PROPN
dti-1329	132	3	.	.	PUNCT
dti-1329	133	1	invest	invest	PROPN
dti-1329	133	2	.	.	PUNCT
dti-1329	134	1	,	,	PUNCT
dti-1329	134	2	61:1428–40	61:1428–40	NUM
dti-1329	134	3	.	.	PUNCT
dti-1329	134	4	stintzi	stintzi	PROPN
dti-1329	134	5	,	,	PUNCT
dti-1329	134	6	a.	a.	PROPN
dti-1329	134	7	,	,	PUNCT
dti-1329	134	8	barnes	barnes	PROPN
dti-1329	134	9	,	,	PUNCT
dti-1329	134	10	c.	c.	PROPN
dti-1329	134	11	,	,	PUNCT
dti-1329	134	12	xu	xu	PROPN
dti-1329	134	13	,	,	PUNCT
dti-1329	134	14	j.	j.	PROPN
dti-1329	134	15	and	and	CCONJ
dti-1329	134	16	raymond	raymond	PROPN
dti-1329	134	17	,	,	PUNCT
dti-1329	134	18	k.n	k.n	PROPN
dti-1329	134	19	.	.	PROPN
dti-1329	134	20	2000	2000	NUM
dti-1329	134	21	.	.	PUNCT
dti-1329	135	1	microbial	microbial	ADJ
dti-1329	135	2	iron	iron	NOUN
dti-1329	135	3	transport	transport	NOUN
dti-1329	135	4	via	via	ADP
dti-1329	135	5	a	a	DET
dti-1329	135	6	siderophore	siderophore	ADJ
dti-1329	135	7	shuttle	shuttle	NOUN
dti-1329	135	8	:	:	PUNCT
dti-1329	135	9	a	a	DET
dti-1329	135	10	membrane	membrane	NOUN
dti-1329	135	11	ion	ion	NOUN
dti-1329	135	12	transport	transport	NOUN
dti-1329	135	13	paradigm	paradigm	NOUN
dti-1329	135	14	.	.	PUNCT
dti-1329	136	1	proc	proc	NOUN
dti-1329	136	2	.	.	PUNCT
dti-1329	137	1	natl	natl	PROPN
dti-1329	137	2	.	.	PUNCT
dti-1329	138	1	acad	acad	PROPN
dti-1329	138	2	.	.	PUNCT
dti-1329	139	1	sci	sci	PROPN
dti-1329	139	2	.	.	PROPN
dti-1329	139	3	,	,	PUNCT
dti-1329	139	4	97:10691–6	97:10691–6	NUM
dti-1329	139	5	.	.	PUNCT
dti-1329	140	1	thompson	thompson	PROPN
dti-1329	140	2	,	,	PUNCT
dti-1329	140	3	j.d	j.d	PROPN
dti-1329	140	4	.	.	PROPN
dti-1329	140	5	,	,	PUNCT
dti-1329	140	6	higgins	higgins	PROPN
dti-1329	140	7	,	,	PUNCT
dti-1329	140	8	d.g	d.g	PROPN
dti-1329	140	9	.	.	PROPN
dti-1329	140	10	and	and	CCONJ
dti-1329	140	11	gibson	gibson	PROPN
dti-1329	140	12	,	,	PUNCT
dti-1329	140	13	t.j	t.j	PROPN
dti-1329	140	14	.	.	PROPN
dti-1329	140	15	1994	1994	NUM
dti-1329	140	16	.	.	PUNCT
dti-1329	141	1	clustal	clustal	PROPN
dti-1329	141	2	w	w	NOUN
dti-1329	141	3	:	:	PUNCT
dti-1329	141	4	improving	improve	VERB
dti-1329	141	5	the	the	DET
dti-1329	141	6	sensitivity	sensitivity	NOUN
dti-1329	141	7	of	of	ADP
dti-1329	141	8	progressive	progressive	ADJ
dti-1329	141	9	multiple	multiple	ADJ
dti-1329	141	10	sequence	sequence	NOUN
dti-1329	141	11	alignment	alignment	NOUN
dti-1329	141	12	through	through	ADP
dti-1329	141	13	sequence	sequence	NOUN
dti-1329	141	14	weighting	weighting	NOUN
dti-1329	141	15	,	,	PUNCT
dti-1329	141	16	position	position	NOUN
dti-1329	141	17	-	-	PUNCT
dti-1329	141	18	specifi	specifi	PROPN
dti-1329	141	19	c	c	PROPN
dti-1329	141	20	gap	gap	NOUN
dti-1329	141	21	penalties	penalty	NOUN
dti-1329	141	22	and	and	CCONJ
dti-1329	141	23	weight	weight	NOUN
dti-1329	141	24	matrix	matrix	NOUN
dti-1329	141	25	choice	choice	NOUN
dti-1329	141	26	.	.	PUNCT
dti-1329	142	1	nucleic	nucleic	ADJ
dti-1329	142	2	acids	acid	NOUN
dti-1329	142	3	res	re	NOUN
dti-1329	142	4	.	.	PROPN
dti-1329	142	5	,	,	PUNCT
dti-1329	142	6	22:4673–80	22:4673–80	NUM
dti-1329	142	7	.	.	PUNCT
dti-1329	143	1	venturi	venturi	PROPN
dti-1329	143	2	,	,	PUNCT
dti-1329	143	3	v.	v.	ADV
dti-1329	143	4	,	,	PUNCT
dti-1329	143	5	ottevanger	ottevanger	PROPN
dti-1329	143	6	,	,	PUNCT
dti-1329	143	7	c.	c.	NOUN
dti-1329	143	8	,	,	PUNCT
dti-1329	143	9	bracke	bracke	NOUN
dti-1329	143	10	,	,	PUNCT
dti-1329	143	11	m.	m.	NOUN
dti-1329	143	12	and	and	CCONJ
dti-1329	143	13	weisbeek	weisbeek	VERB
dti-1329	143	14	,	,	PUNCT
dti-1329	143	15	p.	p.	NOUN
dti-1329	143	16	1995	1995	NUM
dti-1329	143	17	.	.	PUNCT
dti-1329	144	1	iron	iron	NOUN
dti-1329	144	2	regulation	regulation	NOUN
dti-1329	144	3	of	of	ADP
dti-1329	144	4	siderophore	siderophore	ADJ
dti-1329	144	5	biosynthesis	biosynthesis	NOUN
dti-1329	144	6	and	and	CCONJ
dti-1329	144	7	transport	transport	NOUN
dti-1329	144	8	in	in	ADP
dti-1329	144	9	pseudomonas	pseudomona	NOUN
dti-1329	144	10	putida	putida	PROPN
dti-1329	144	11	wcs358	wcs358	NOUN
dti-1329	144	12	:	:	PUNCT
dti-1329	144	13	involvement	involvement	NOUN
dti-1329	144	14	of	of	ADP
dti-1329	144	15	a	a	DET
dti-1329	144	16	transcriptional	transcriptional	ADJ
dti-1329	144	17	activator	activator	NOUN
dti-1329	144	18	and	and	CCONJ
dti-1329	144	19	of	of	ADP
dti-1329	144	20	the	the	DET
dti-1329	144	21	fur	fur	NOUN
dti-1329	144	22	protein	protein	NOUN
dti-1329	144	23	.	.	PUNCT
dti-1329	145	1	mol	mol	PROPN
dti-1329	145	2	.	.	PROPN
dti-1329	145	3	microbiol	microbiol	PROPN
dti-1329	145	4	.	.	PUNCT
dti-1329	145	5	,	,	PUNCT
dti-1329	145	6	15:1081–93	15:1081–93	NUM
dti-1329	145	7	.	.	PUNCT
dti-1329	146	1	wooldridge	wooldridge	PROPN
dti-1329	146	2	,	,	PUNCT
dti-1329	146	3	k.g	k.g	PROPN
dti-1329	146	4	.	.	PROPN
dti-1329	146	5	and	and	CCONJ
dti-1329	146	6	williams	williams	PROPN
dti-1329	146	7	,	,	PUNCT
dti-1329	146	8	p.h	p.h	PROPN
dti-1329	146	9	.	.	PROPN
dti-1329	146	10	1993	1993	NUM
dti-1329	146	11	.	.	PUNCT
dti-1329	147	1	iron	iron	NOUN
dti-1329	147	2	uptake	uptake	ADJ
dti-1329	147	3	mechanisms	mechanism	NOUN
dti-1329	147	4	of	of	ADP
dti-1329	147	5	pathogenic	pathogenic	ADJ
dti-1329	147	6	bacteria	bacteria	NOUN
dti-1329	147	7	.	.	PUNCT
dti-1329	148	1	fems	fems	PROPN
dti-1329	148	2	microbiol	microbiol	PROPN
dti-1329	148	3	.	.	PUNCT
dti-1329	149	1	rev	rev	PROPN
dti-1329	149	2	.	.	PROPN
dti-1329	149	3	,	,	PUNCT
dti-1329	149	4	12:325	12:325	NUM
dti-1329	149	5	.	.	PUNCT
dti-1329	150	1	figure	figure	NOUN
dti-1329	150	2	4	4	NUM
dti-1329	150	3	.	.	PUNCT
dti-1329	150	4	predicted	predict	VERB
dti-1329	150	5	crystal	crystal	NOUN
dti-1329	150	6	structure	structure	NOUN
dti-1329	150	7	of	of	ADP
dti-1329	150	8	the	the	DET
dti-1329	150	9	gene	gene	NOUN
dti-1329	150	10	product	product	NOUN
dti-1329	150	11	of	of	ADP
dti-1329	150	12	nsr1	nsr1	PROPN
dti-1329	150	13	(	(	PUNCT
dti-1329	150	14	bates	bate	NOUN
dti-1329	150	15	et	et	PROPN
dti-1329	150	16	al	al	PROPN
dti-1329	150	17	.	.	PROPN
dti-1329	150	18	2001	2001	NUM
dti-1329	150	19	;	;	PUNCT
dti-1329	150	20	bates	bate	NOUN
dti-1329	150	21	and	and	CCONJ
dti-1329	150	22	sternberg	sternberg	PROPN
dti-1329	150	23	,	,	PUNCT
dti-1329	150	24	1999	1999	NUM
dti-1329	150	25	;	;	PUNCT
dti-1329	150	26	contreras	contreras	PROPN
dti-1329	150	27	-	-	PUNCT
dti-1329	150	28	moreira	moreira	PROPN
dti-1329	150	29	and	and	CCONJ
dti-1329	150	30	bates	bate	NOUN
dti-1329	150	31	,	,	PUNCT
dti-1329	150	32	2002	2002	NUM
dti-1329	150	33	)	)	PUNCT
dti-1329	151	1	(	(	PUNCT
dti-1329	151	2	3d	3d	NUM
dti-1329	151	3	-	-	PUNCT
dti-1329	151	4	jigsaw	jigsaw	NOUN
dti-1329	151	5	protein	protein	NOUN
dti-1329	151	6	comparative	comparative	ADJ
dti-1329	151	7	modeling	modeling	NOUN
dti-1329	151	8	server	server	NOUN
dti-1329	151	9	,	,	PUNCT
dti-1329	151	10	uk	uk	PROPN
dti-1329	151	11	)	)	PUNCT
dti-1329	151	12	.	.	PUNCT
dti-1329	152	1	the	the	DET
dti-1329	152	2	structure	structure	NOUN
dti-1329	152	3	bears	bear	VERB
dti-1329	152	4	striking	strike	VERB
dti-1329	152	5	similarity	similarity	NOUN
dti-1329	152	6	to	to	ADP
dti-1329	152	7	all	all	DET
dti-1329	152	8	other	other	ADJ
dti-1329	152	9	currently	currently	ADV
dti-1329	152	10	known	know	VERB
dti-1329	152	11	ferric	ferric	ADJ
dti-1329	152	12	siderophore	siderophore	NOUN
dti-1329	152	13	receptors	receptor	NOUN
dti-1329	152	14	.	.	PUNCT
dti-1329	153	1	the	the	DET
dti-1329	153	2	putative	putative	ADJ
dti-1329	153	3	protein	protein	NOUN
dti-1329	153	4	is	be	AUX
dti-1329	153	5	comprised	comprise	VERB
dti-1329	153	6	of	of	ADP
dti-1329	153	7	an	an	DET
dti-1329	153	8	antiparallel	antiparallel	ADJ
dti-1329	153	9	β	β	NOUN
dti-1329	153	10	-	-	PUNCT
dti-1329	153	11	barrel	barrel	NOUN
dti-1329	153	12	enclosing	enclose	VERB
dti-1329	153	13	the	the	DET
dti-1329	153	14	iron	iron	NOUN
dti-1329	153	15	removal	removal	NOUN
dti-1329	153	16	site	site	NOUN
dti-1329	153	17	within	within	ADP
dti-1329	153	18	the	the	DET
dti-1329	153	19	receptor	receptor	NOUN
dti-1329	153	20	,	,	PUNCT
dti-1329	153	21	as	as	ADV
dti-1329	153	22	well	well	ADV
dti-1329	153	23	as	as	ADP
dti-1329	153	24	an	an	DET
dti-1329	153	25	n	n	CCONJ
dti-1329	153	26	-	-	PUNCT
dti-1329	153	27	terminal	terminal	ADJ
dti-1329	153	28	globular	globular	ADJ
dti-1329	153	29	domain	domain	NOUN
dti-1329	153	30	that	that	PRON
dti-1329	153	31	forms	form	VERB
dti-1329	153	32	surface	surface	NOUN
dti-1329	153	33	loops	loop	NOUN
dti-1329	153	34	and	and	CCONJ
dti-1329	153	35	folds	fold	NOUN
dti-1329	153	36	down	down	ADP
dti-1329	153	37	into	into	ADP
dti-1329	153	38	the	the	DET
dti-1329	153	39	interior	interior	NOUN
dti-1329	153	40	of	of	ADP
dti-1329	153	41	the	the	DET
dti-1329	153	42	β	β	NOUN
dti-1329	153	43	-	-	NOUN
dti-1329	153	44	barrel	barrel	NOUN
dti-1329	153	45	.	.	PUNCT
dti-1329	154	1	protein	protein	NOUN
dti-1329	154	2	is	be	AUX
dti-1329	154	3	colored	color	VERB
dti-1329	154	4	by	by	ADP
dti-1329	154	5	secondary	secondary	ADJ
dti-1329	154	6	structure	structure	NOUN
dti-1329	154	7	(	(	PUNCT
dti-1329	154	8	red	red	ADJ
dti-1329	154	9	helices	helix	NOUN
dti-1329	154	10	,	,	PUNCT
dti-1329	154	11	yellow	yellow	ADJ
dti-1329	154	12	sheets	sheet	NOUN
dti-1329	154	13	,	,	PUNCT
dti-1329	154	14	green	green	ADJ
dti-1329	154	15	loops	loop	NOUN
dti-1329	154	16	)	)	PUNCT
dti-1329	154	17	.	.	PUNCT
dti-1329	155	1	<	<	X
dti-1329	155	2	<	<	X
dti-1329	155	3	/ascii85encodepages	/ascii85encodepage	NOUN
dti-1329	155	4	false	false	ADJ
dti-1329	155	5	/allowtransparency	/allowtransparency	NOUN
dti-1329	155	6	false	false	ADJ
dti-1329	155	7	/autopositionepsfiles	/autopositionepsfile	NOUN
dti-1329	155	8	true	true	ADJ
dti-1329	155	9	/autorotatepages	/autorotatepage	NOUN
dti-1329	155	10	/none	/none	PUNCT
dti-1329	155	11	/binding	/binding	PUNCT
dti-1329	155	12	/left	/left	ADJ
dti-1329	156	1	/calgrayprofile	/calgrayprofile	VERB
dti-1329	156	2	(	(	PUNCT
dti-1329	156	3	dot	dot	NOUN
dti-1329	156	4	gain	gain	NOUN
dti-1329	156	5	20	20	NUM
dti-1329	156	6	%	%	NOUN
dti-1329	156	7	)	)	PUNCT
dti-1329	156	8	/calrgbprofile	/calrgbprofile	PUNCT
dti-1329	157	1	(	(	PUNCT
dti-1329	157	2	srgb	srgb	PROPN
dti-1329	157	3	iec61966	iec61966	NOUN
dti-1329	157	4	-	-	PUNCT
dti-1329	157	5	2.1	2.1	NUM
dti-1329	157	6	)	)	PUNCT
dti-1329	157	7	/calcmykprofile	/calcmykprofile	PUNCT
dti-1329	158	1	(	(	PUNCT
dti-1329	158	2	u.s	u.s	PROPN
dti-1329	158	3	.	.	PROPN
dti-1329	158	4	web	web	NOUN
dti-1329	158	5	coated	coat	VERB
dti-1329	158	6	\050swop\051	\050swop\051	ADJ
dti-1329	158	7	v2	v2	NOUN
dti-1329	158	8	)	)	PUNCT
dti-1329	158	9	/srgbprofile	/srgbprofile	PUNCT
dti-1329	158	10	(	(	PUNCT
dti-1329	158	11	srgb	srgb	PROPN
dti-1329	158	12	iec61966	iec61966	NOUN
dti-1329	158	13	-	-	PUNCT
dti-1329	158	14	2.1	2.1	NUM
dti-1329	158	15	)	)	PUNCT
dti-1329	158	16	/cannotembedfontpolicy	/cannotembedfontpolicy	PUNCT
dti-1329	159	1	/error	/error	INTJ
dti-1329	159	2	/compatibilitylevel	/compatibilitylevel	NOUN
dti-1329	160	1	1.4	1.4	NUM
dti-1329	160	2	/compressobjects	/compressobject	NOUN
dti-1329	160	3	/tags	/tag	VERB
dti-1329	160	4	/compresspages	/compresspage	NOUN
dti-1329	160	5	true	true	ADJ
dti-1329	160	6	/convertimagestoindexed	/convertimagestoindexed	ADJ
dti-1329	160	7	true	true	ADJ
dti-1329	160	8	/passthroughjpegimages	/passthroughjpegimage	NOUN
dti-1329	160	9	true	true	ADJ
dti-1329	160	10	/createjdffile	/createjdffile	ADJ
dti-1329	160	11	false	false	ADJ
dti-1329	160	12	/createjobticket	/createjobticket	NOUN
dti-1329	160	13	false	false	ADJ
dti-1329	160	14	/defaultrenderingintent	/defaultrenderingintent	NOUN
dti-1329	160	15	/default	/default	PUNCT
dti-1329	160	16	/detectblends	/detectblend	NOUN
dti-1329	160	17	true	true	ADJ
dti-1329	160	18	/colorconversionstrategy	/colorconversionstrategy	NOUN
dti-1329	160	19	/leavecolorunchanged	/leavecolorunchange	VERB
dti-1329	160	20	/dothumbnails	/dothumbnail	VERB
dti-1329	160	21	false	false	ADJ
dti-1329	160	22	/embedallfonts	/embedallfont	NOUN
dti-1329	160	23	true	true	ADJ
dti-1329	160	24	/embedjoboptions	/embedjoboption	NOUN
dti-1329	160	25	true	true	ADJ
dti-1329	160	26	/dscreportinglevel	/dscreportinglevel	NOUN
dti-1329	160	27	0	0	NUM
dti-1329	160	28	/emitdscwarnings	/emitdscwarning	NOUN
dti-1329	160	29	false	false	ADJ
dti-1329	160	30	/endpage	/endpage	NOUN
dti-1329	160	31	-1	-1	NOUN
dti-1329	160	32	/imagememory	/imagememory	NUM
dti-1329	161	1	1048576	1048576	NUM
dti-1329	161	2	/lockdistillerparams	/lockdistillerparams	NOUN
dti-1329	161	3	false	false	ADJ
dti-1329	161	4	/maxsubsetpct	/maxsubsetpct	ADJ
dti-1329	161	5	100	100	NUM
dti-1329	161	6	/optimize	/optimize	NOUN
dti-1329	161	7	true	true	ADJ
dti-1329	161	8	/opm	/opm	NOUN
dti-1329	161	9	1	1	NUM
dti-1329	161	10	/parsedsccomments	/parsedsccomment	NOUN
dti-1329	161	11	true	true	ADJ
dti-1329	161	12	/parsedsccommentsfordocinfo	/parsedsccommentsfordocinfo	VERB
dti-1329	161	13	true	true	ADJ
dti-1329	161	14	/preservecopypage	/preservecopypage	NOUN
dti-1329	161	15	true	true	ADJ
dti-1329	161	16	/preserveepsinfo	/preserveepsinfo	NOUN
dti-1329	161	17	true	true	ADJ
dti-1329	161	18	/preservehalftoneinfo	/preservehalftoneinfo	PUNCT
dti-1329	161	19	false	false	ADJ
dti-1329	161	20	/preserveopicomments	/preserveopicomment	NOUN
dti-1329	161	21	false	false	ADJ
dti-1329	161	22	/preserveoverprintsettings	/preserveoverprintsetting	NOUN
dti-1329	161	23	true	true	ADJ
dti-1329	161	24	/startpage	/startpage	NOUN
dti-1329	161	25	1	1	NUM
dti-1329	161	26	/subsetfonts	/subsetfont	NOUN
dti-1329	161	27	true	true	ADJ
dti-1329	161	28	/transferfunctioninfo	/transferfunctioninfo	PUNCT
dti-1329	161	29	/apply	/apply	PUNCT
dti-1329	161	30	/ucrandbginfo	/ucrandbginfo	PUNCT
dti-1329	162	1	/preserve	/preserve	NOUN
dti-1329	162	2	/useprologue	/useprologue	NOUN
dti-1329	162	3	false	false	ADJ
dti-1329	162	4	/colorsettingsfile	/colorsettingsfile	NOUN
dti-1329	162	5	(	(	PUNCT
dti-1329	162	6	)	)	PUNCT
dti-1329	162	7	/alwaysembed	/alwaysembe	VERB
dti-1329	162	8	[	[	PUNCT
dti-1329	162	9	true	true	ADJ
dti-1329	162	10	]	]	PUNCT
dti-1329	162	11	/neverembed	/neverembed	PUNCT
dti-1329	163	1	[	[	PUNCT
dti-1329	163	2	true	true	ADJ
dti-1329	163	3	]	]	PUNCT
dti-1329	163	4	/antialiascolorimages	/antialiascolorimages	X
dti-1329	163	5	false	false	ADJ
dti-1329	163	6	/downsamplecolorimages	/downsamplecolorimage	NOUN
dti-1329	163	7	true	true	ADJ
dti-1329	163	8	/colorimagedownsampletype	/colorimagedownsampletype	PUNCT
dti-1329	163	9	/bicubic	/bicubic	NOUN
dti-1329	163	10	/colorimageresolution	/colorimageresolution	NOUN
dti-1329	163	11	300	300	NUM
dti-1329	163	12	/colorimagedepth	/colorimagedepth	PRON
dti-1329	164	1	-1	-1	INTJ
dti-1329	164	2	/colorimagedownsamplethreshold	/colorimagedownsamplethreshold	PUNCT
dti-1329	164	3	1.50000	1.50000	NUM
dti-1329	164	4	/encodecolorimages	/encodecolorimage	NOUN
dti-1329	164	5	true	true	ADJ
dti-1329	164	6	/colorimagefilter	/colorimagefilter	PUNCT
dti-1329	164	7	/dctencode	/dctencode	PUNCT
dti-1329	164	8	/autofiltercolorimages	/autofiltercolorimage	NOUN
dti-1329	164	9	true	true	ADJ
dti-1329	164	10	/colorimageautofilterstrategy	/colorimageautofilterstrategy	PUNCT
dti-1329	164	11	/jpeg	/jpeg	PUNCT
dti-1329	164	12	/coloracsimagedict	/coloracsimagedict	PUNCT
dti-1329	165	1	<	<	X
dti-1329	165	2	<	<	X
dti-1329	165	3	/qfactor	/qfactor	NOUN
dti-1329	165	4	0.15	0.15	NUM
dti-1329	165	5	/hsamples	/hsample	NOUN
dti-1329	166	1	[	[	X
dti-1329	166	2	1	1	NUM
dti-1329	166	3	1	1	NUM
dti-1329	166	4	1	1	NUM
dti-1329	166	5	1	1	NUM
dti-1329	166	6	]	]	PUNCT
dti-1329	166	7	/vsamples	/vsample	NOUN
dti-1329	167	1	[	[	X
dti-1329	167	2	1	1	NUM
dti-1329	167	3	1	1	NUM
dti-1329	167	4	1	1	NUM
dti-1329	167	5	1	1	NUM
dti-1329	167	6	]	]	PUNCT
dti-1329	167	7	>	>	PUNCT
dti-1329	167	8	>	>	X
dti-1329	167	9	/colorimagedict	/colorimagedict	PUNCT
dti-1329	168	1	<	<	X
dti-1329	168	2	<	<	X
dti-1329	168	3	/qfactor	/qfactor	NOUN
dti-1329	168	4	0.15	0.15	NUM
dti-1329	168	5	/hsamples	/hsample	NOUN
dti-1329	169	1	[	[	X
dti-1329	169	2	1	1	NUM
dti-1329	169	3	1	1	NUM
dti-1329	169	4	1	1	NUM
dti-1329	169	5	1	1	NUM
dti-1329	169	6	]	]	PUNCT
dti-1329	169	7	/vsamples	/vsample	NOUN
dti-1329	170	1	[	[	X
dti-1329	170	2	1	1	NUM
dti-1329	170	3	1	1	NUM
dti-1329	170	4	1	1	NUM
dti-1329	170	5	1	1	NUM
dti-1329	170	6	]	]	PUNCT
dti-1329	170	7	>	>	PUNCT
dti-1329	170	8	>	>	X
dti-1329	170	9	/jpeg2000coloracsimagedict	/jpeg2000coloracsimagedict	PUNCT
dti-1329	171	1	<	<	X
dti-1329	171	2	<	<	X
dti-1329	171	3	/tilewidth	/tilewidth	PUNCT
dti-1329	171	4	256	256	NUM
dti-1329	171	5	/tileheight	/tileheight	NUM
dti-1329	171	6	256	256	NUM
dti-1329	171	7	/quality	/quality	NOUN
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dti-1329	171	9	>	>	PUNCT
dti-1329	171	10	>	>	X
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dti-1329	171	12	<	<	X
dti-1329	171	13	<	<	X
dti-1329	171	14	/tilewidth	/tilewidth	PUNCT
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dti-1329	171	18	/quality	/quality	NOUN
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dti-1329	171	20	>	>	PUNCT
dti-1329	171	21	>	>	X
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dti-1329	171	23	false	false	ADJ
dti-1329	171	24	/downsamplegrayimages	/downsamplegrayimage	NOUN
dti-1329	172	1	true	true	ADJ
dti-1329	172	2	/grayimagedownsampletype	/grayimagedownsampletype	NOUN
dti-1329	172	3	/bicubic	/bicubic	NOUN
dti-1329	172	4	/grayimageresolution	/grayimageresolution	NOUN
dti-1329	172	5	300	300	NUM
dti-1329	172	6	/grayimagedepth	/grayimagedepth	PUNCT
dti-1329	172	7	-1	-1	PUNCT
dti-1329	172	8	/grayimagedownsamplethreshold	/grayimagedownsamplethreshold	PRON
dti-1329	173	1	1.50000	1.50000	NUM
dti-1329	173	2	/encodegrayimages	/encodegrayimage	NOUN
dti-1329	173	3	true	true	ADJ
dti-1329	173	4	/grayimagefilter	/grayimagefilter	NOUN
dti-1329	173	5	/dctencode	/dctencode	PUNCT
dti-1329	174	1	/autofiltergrayimages	/autofiltergrayimages	VERB
dti-1329	174	2	true	true	ADJ
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dti-1329	174	4	/jpeg	/jpeg	PUNCT
dti-1329	174	5	/grayacsimagedict	/grayacsimagedict	PUNCT
dti-1329	175	1	<	<	X
dti-1329	175	2	<	<	X
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dti-1329	176	1	[	[	X
dti-1329	176	2	1	1	NUM
dti-1329	176	3	1	1	NUM
dti-1329	176	4	1	1	NUM
dti-1329	176	5	1	1	NUM
dti-1329	176	6	]	]	PUNCT
dti-1329	176	7	/vsamples	/vsample	NOUN
dti-1329	177	1	[	[	X
dti-1329	177	2	1	1	NUM
dti-1329	177	3	1	1	NUM
dti-1329	177	4	1	1	NUM
dti-1329	177	5	1	1	NUM
dti-1329	177	6	]	]	PUNCT
dti-1329	177	7	>	>	PUNCT
dti-1329	177	8	>	>	X
dti-1329	177	9	/grayimagedict	/grayimagedict	PUNCT
dti-1329	178	1	<	<	X
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dti-1329	178	4	0.15	0.15	NUM
dti-1329	178	5	/hsamples	/hsample	NOUN
dti-1329	179	1	[	[	X
dti-1329	179	2	1	1	NUM
dti-1329	179	3	1	1	NUM
dti-1329	179	4	1	1	NUM
dti-1329	179	5	1	1	NUM
dti-1329	179	6	]	]	PUNCT
dti-1329	179	7	/vsamples	/vsample	NOUN
dti-1329	180	1	[	[	X
dti-1329	180	2	1	1	NUM
dti-1329	180	3	1	1	NUM
dti-1329	180	4	1	1	NUM
dti-1329	180	5	1	1	NUM
dti-1329	180	6	]	]	PUNCT
dti-1329	180	7	>	>	X
dti-1329	180	8	>	>	X
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dti-1329	181	1	<	<	X
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dti-1329	181	5	/tileheight	/tileheight	NUM
dti-1329	181	6	256	256	NUM
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dti-1329	181	9	>	>	PUNCT
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dti-1329	183	4	/pdfx3check	/pdfx3check	PUNCT
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dti-1329	183	7	false	false	ADJ
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dti-1329	185	4	(	(	PUNCT
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dti-1329	185	8	http://www.color.org	http://www.color.org	PROPN
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dti-1329	186	7	/fra	/fra	PUNCT
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dti-1329	187	3	>	>	X
dti-1329	187	4	/deu	/deu	PUNCT
dti-1329	188	1	<	<	X
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dti-1329	188	3	>	>	X
dti-1329	188	4	/ptb	/ptb	PROPN
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dti-1329	190	2	>	>	X
dti-1329	190	3	/dan	/dan	PUNCT
dti-1329	191	1	<	<	X
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dti-1329	191	3	>	>	X
dti-1329	191	4	/nld	/nld	PUNCT
dti-1329	192	1	<	<	X
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dti-1329	192	3	>	>	X
dti-1329	192	4	/esp	/esp	PUNCT
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dti-1329	193	3	>	>	X
dti-1329	193	4	/suo	/suo	PUNCT
dti-1329	194	1	<	<	X
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dti-1329	194	3	>	>	X
dti-1329	194	4	/ita	/ita	PUNCT
dti-1329	195	1	<	<	X
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dti-1329	195	3	>	>	X
dti-1329	195	4	/nor	/nor	X
dti-1329	195	5	<	<	X
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dti-1329	195	7	>	>	X
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