id	sid	tid	token	lemma	pos
dti-1333	1	1	brown	brown	PROPN
dti-1333	1	2	et	et	PROPN
dti-1333	1	3	al.indd	al.indd	X
dti-1333	1	4	drug	drug	NOUN
dti-1333	1	5	target	target	NOUN
dti-1333	1	6	insights	insight	NOUN
dti-1333	1	7	2008:3	2008:3	NUM
dti-1333	1	8	45–54	45–54	NUM
dti-1333	1	9	45	45	NUM
dti-1333	1	10	review	review	NOUN
dti-1333	1	11	correspondence	correspondence	NOUN
dti-1333	1	12	:	:	PUNCT
dti-1333	1	13	william	william	PROPN
dti-1333	1	14	m.	m.	PROPN
dti-1333	1	15	brown	brown	PROPN
dti-1333	1	16	,	,	PUNCT
dti-1333	1	17	ph.d	ph.d	PROPN
dti-1333	1	18	.	.	PROPN
dti-1333	1	19	,	,	PUNCT
dti-1333	1	20	j.d	j.d	PROPN
dti-1333	1	21	.	.	PROPN
dti-1333	1	22	,	,	PUNCT
dti-1333	1	23	resverlogix	resverlogix	PROPN
dti-1333	1	24	corp	corp	PROPN
dti-1333	1	25	.	.	PROPN
dti-1333	1	26	,	,	PUNCT
dti-1333	1	27	202	202	NUM
dti-1333	1	28	,	,	PUNCT
dti-1333	1	29	279	279	NUM
dti-1333	1	30	midpark	midpark	NOUN
dti-1333	1	31	way	way	NOUN
dti-1333	1	32	se	se	X
dti-1333	1	33	,	,	PUNCT
dti-1333	1	34	calgary	calgary	PROPN
dti-1333	1	35	,	,	PUNCT
dti-1333	1	36	ab	ab	PROPN
dti-1333	1	37	t2x	t2x	NOUN
dti-1333	1	38	1m2	1m2	NUM
dti-1333	1	39	,	,	PUNCT
dti-1333	1	40	canada	canada	PROPN
dti-1333	1	41	.	.	PUNCT
dti-1333	2	1	tel	tel	ADP
dti-1333	2	2	:	:	PUNCT
dti-1333	2	3	403	403	NUM
dti-1333	2	4	-	-	SYM
dti-1333	2	5	254	254	NUM
dti-1333	2	6	-	-	PUNCT
dti-1333	2	7	9252	9252	NUM
dti-1333	2	8	;	;	PUNCT
dti-1333	2	9	fax	fax	NOUN
dti-1333	2	10	:	:	PUNCT
dti-1333	2	11	403	403	NUM
dti-1333	2	12	-	-	SYM
dti-1333	2	13	256	256	NUM
dti-1333	2	14	-	-	PUNCT
dti-1333	2	15	8495	8495	NUM
dti-1333	2	16	;	;	PUNCT
dti-1333	2	17	email	email	NOUN
dti-1333	2	18	:	:	PUNCT
dti-1333	2	19	william@resverlogix.com	william@resverlogix.com	X
dti-1333	3	1	copyright	copyright	NOUN
dti-1333	3	2	in	in	ADP
dti-1333	3	3	this	this	DET
dti-1333	3	4	article	article	NOUN
dti-1333	3	5	,	,	PUNCT
dti-1333	3	6	its	its	PRON
dti-1333	3	7	metadata	metadata	NOUN
dti-1333	3	8	,	,	PUNCT
dti-1333	3	9	and	and	CCONJ
dti-1333	3	10	any	any	DET
dti-1333	3	11	supplementary	supplementary	ADJ
dti-1333	3	12	data	datum	NOUN
dti-1333	3	13	is	be	AUX
dti-1333	3	14	held	hold	VERB
dti-1333	3	15	by	by	ADP
dti-1333	3	16	its	its	PRON
dti-1333	3	17	author	author	NOUN
dti-1333	3	18	or	or	CCONJ
dti-1333	3	19	authors	author	NOUN
dti-1333	3	20	.	.	PUNCT
dti-1333	4	1	it	it	PRON
dti-1333	4	2	is	be	AUX
dti-1333	4	3	published	publish	VERB
dti-1333	4	4	under	under	ADP
dti-1333	4	5	the	the	DET
dti-1333	4	6	creative	creative	ADJ
dti-1333	4	7	commons	common	NOUN
dti-1333	4	8	attribution	attribution	NOUN
dti-1333	4	9	by	by	ADP
dti-1333	4	10	licence	licence	NOUN
dti-1333	4	11	.	.	PUNCT
dti-1333	5	1	for	for	SCONJ
dti-1333	5	2	further	further	ADJ
dti-1333	5	3	information	information	NOUN
dti-1333	5	4	go	go	VERB
dti-1333	5	5	to	to	ADP
dti-1333	5	6	:	:	PUNCT
dti-1333	5	7	http://creativecommons.org/licenses/by/3.0/.	http://creativecommons.org/licenses/by/3.0/.	VERB
dti-1333	5	8	therapies	therapy	NOUN
dti-1333	5	9	to	to	PART
dti-1333	5	10	increase	increase	VERB
dti-1333	5	11	apoa	apoa	NOUN
dti-1333	5	12	-	-	PUNCT
dti-1333	5	13	i	i	PROPN
dti-1333	5	14	and	and	CCONJ
dti-1333	5	15	hdl	hdl	PROPN
dti-1333	5	16	-	-	PUNCT
dti-1333	5	17	cholesterol	cholesterol	NOUN
dti-1333	5	18	levels	level	NOUN
dti-1333	5	19	william	william	PROPN
dti-1333	5	20	m.	m.	PROPN
dti-1333	5	21	brown	brown	PROPN
dti-1333	5	22	and	and	CCONJ
dti-1333	5	23	fabrizio	fabrizio	PROPN
dti-1333	5	24	s.	s.	PROPN
dti-1333	5	25	chiacchia	chiacchia	PROPN
dti-1333	5	26	resverlogix	resverlogix	PROPN
dti-1333	5	27	corp	corp	PROPN
dti-1333	5	28	.	.	PROPN
dti-1333	5	29	,	,	PUNCT
dti-1333	5	30	202	202	NUM
dti-1333	5	31	,	,	PUNCT
dti-1333	5	32	279	279	NUM
dti-1333	5	33	midpark	midpark	NOUN
dti-1333	5	34	way	way	NOUN
dti-1333	5	35	se	se	X
dti-1333	5	36	,	,	PUNCT
dti-1333	5	37	calgary	calgary	PROPN
dti-1333	5	38	,	,	PUNCT
dti-1333	5	39	ab	ab	PROPN
dti-1333	5	40	t2x	t2x	NOUN
dti-1333	5	41	1m2	1m2	NUM
dti-1333	5	42	,	,	PUNCT
dti-1333	5	43	canada	canada	PROPN
dti-1333	5	44	.	.	PUNCT
dti-1333	6	1	abstract	abstract	ADJ
dti-1333	6	2	:	:	PUNCT
dti-1333	6	3	cholesterol	cholesterol	NOUN
dti-1333	6	4	is	be	AUX
dti-1333	6	5	transported	transport	VERB
dti-1333	6	6	around	around	ADP
dti-1333	6	7	the	the	DET
dti-1333	6	8	body	body	NOUN
dti-1333	6	9	in	in	ADP
dti-1333	6	10	the	the	DET
dti-1333	6	11	form	form	NOUN
dti-1333	6	12	of	of	ADP
dti-1333	6	13	lipoprotein	lipoprotein	ADJ
dti-1333	6	14	(	(	PUNCT
dti-1333	6	15	lipid	lipid	NOUN
dti-1333	6	16	/	/	SYM
dti-1333	6	17	protein	protein	NOUN
dti-1333	6	18	)	)	PUNCT
dti-1333	6	19	complexes	complex	NOUN
dti-1333	6	20	,	,	PUNCT
dti-1333	6	21	because	because	SCONJ
dti-1333	6	22	it	it	PRON
dti-1333	6	23	is	be	AUX
dti-1333	6	24	almost	almost	ADV
dti-1333	6	25	insoluble	insoluble	ADJ
dti-1333	6	26	in	in	ADP
dti-1333	6	27	water	water	NOUN
dti-1333	6	28	.	.	PUNCT
dti-1333	7	1	high	high	ADJ
dti-1333	7	2	-	-	PUNCT
dti-1333	7	3	density	density	NOUN
dti-1333	7	4	lipoprotein	lipoprotein	ADJ
dti-1333	7	5	(	(	PUNCT
dti-1333	7	6	hdl	hdl	NOUN
dti-1333	7	7	)	)	PUNCT
dti-1333	7	8	particles	particle	NOUN
dti-1333	7	9	transport	transport	VERB
dti-1333	7	10	cholesterol	cholesterol	NOUN
dti-1333	7	11	from	from	ADP
dti-1333	7	12	tissues	tissue	NOUN
dti-1333	7	13	back	back	ADV
dti-1333	7	14	to	to	ADP
dti-1333	7	15	the	the	DET
dti-1333	7	16	liver	liver	NOUN
dti-1333	7	17	for	for	ADP
dti-1333	7	18	excretion	excretion	NOUN
dti-1333	7	19	.	.	PUNCT
dti-1333	8	1	epidemiological	epidemiological	ADJ
dti-1333	8	2	studies	study	NOUN
dti-1333	8	3	have	have	AUX
dti-1333	8	4	shown	show	VERB
dti-1333	8	5	an	an	DET
dti-1333	8	6	inverse	inverse	NOUN
dti-1333	8	7	relationship	relationship	NOUN
dti-1333	8	8	between	between	ADP
dti-1333	8	9	blood	blood	NOUN
dti-1333	8	10	levels	level	NOUN
dti-1333	8	11	of	of	ADP
dti-1333	8	12	hdl	hdl	NOUN
dti-1333	8	13	-	-	PUNCT
dti-1333	8	14	cholesterol	cholesterol	NOUN
dti-1333	8	15	(	(	PUNCT
dti-1333	8	16	hdl	hdl	NOUN
dti-1333	8	17	-	-	PUNCT
dti-1333	8	18	c	c	NOUN
dti-1333	8	19	)	)	PUNCT
dti-1333	8	20	and	and	CCONJ
dti-1333	8	21	the	the	DET
dti-1333	8	22	incidence	incidence	NOUN
dti-1333	8	23	of	of	ADP
dti-1333	8	24	clinically	clinically	ADV
dti-1333	8	25	signifi	signifi	NOUN
dti-1333	8	26	ca	can	AUX
dti-1333	8	27	nt	not	PART
dti-1333	8	28	atherosclerosis	atherosclerosis	VERB
dti-1333	8	29	.	.	PUNCT
dti-1333	9	1	the	the	DET
dti-1333	9	2	benefi	benefi	PROPN
dti-1333	9	3	cial	cial	ADJ
dti-1333	9	4	effects	effect	NOUN
dti-1333	9	5	of	of	ADP
dti-1333	9	6	hdl	hdl	NOUN
dti-1333	9	7	in	in	ADP
dti-1333	9	8	altering	alter	VERB
dti-1333	9	9	atherosclerotic	atherosclerotic	ADJ
dti-1333	9	10	disease	disease	NOUN
dti-1333	9	11	are	be	AUX
dti-1333	9	12	believed	believe	VERB
dti-1333	9	13	to	to	PART
dti-1333	9	14	involve	involve	VERB
dti-1333	9	15	elevated	elevated	ADJ
dti-1333	9	16	levels	level	NOUN
dti-1333	9	17	of	of	ADP
dti-1333	9	18	hdl	hdl	NOUN
dti-1333	9	19	enhancing	enhance	VERB
dti-1333	9	20	the	the	DET
dti-1333	9	21	effl	effl	NOUN
dti-1333	9	22	ux	ux	PROPN
dti-1333	9	23	of	of	ADP
dti-1333	9	24	cholesterol	cholesterol	NOUN
dti-1333	9	25	from	from	ADP
dti-1333	9	26	arterial	arterial	ADJ
dti-1333	9	27	walls	wall	NOUN
dti-1333	9	28	,	,	PUNCT
dti-1333	9	29	increasing	increase	VERB
dti-1333	9	30	transport	transport	NOUN
dti-1333	9	31	of	of	ADP
dti-1333	9	32	cholesterol	cholesterol	NOUN
dti-1333	9	33	from	from	ADP
dti-1333	9	34	arteries	artery	NOUN
dti-1333	9	35	to	to	ADP
dti-1333	9	36	the	the	DET
dti-1333	9	37	liver	liver	NOUN
dti-1333	9	38	for	for	ADP
dti-1333	9	39	excretion	excretion	NOUN
dti-1333	9	40	.	.	PUNCT
dti-1333	10	1	this	this	DET
dti-1333	10	2	reverse	reverse	ADJ
dti-1333	10	3	cholesterol	cholesterol	NOUN
dti-1333	10	4	transport	transport	NOUN
dti-1333	10	5	(	(	PUNCT
dti-1333	10	6	rct	rct	PROPN
dti-1333	10	7	)	)	PUNCT
dti-1333	10	8	pathway	pathway	NOUN
dti-1333	10	9	is	be	AUX
dti-1333	10	10	used	use	VERB
dti-1333	10	11	to	to	PART
dti-1333	10	12	explain	explain	VERB
dti-1333	10	13	both	both	DET
dti-1333	10	14	hdl	hdl	PROPN
dti-1333	10	15	’s	’s	PART
dti-1333	10	16	role	role	NOUN
dti-1333	10	17	in	in	ADP
dti-1333	10	18	lipid	lipid	ADJ
dti-1333	10	19	metabolism	metabolism	NOUN
dti-1333	10	20	and	and	CCONJ
dti-1333	10	21	the	the	DET
dti-1333	10	22	inverse	inverse	NOUN
dti-1333	10	23	association	association	NOUN
dti-1333	10	24	between	between	ADP
dti-1333	10	25	hdl	hdl	PROPN
dti-1333	10	26	-	-	PUNCT
dti-1333	10	27	c	c	PROPN
dti-1333	10	28	plasma	plasma	NOUN
dti-1333	10	29	concentration	concentration	NOUN
dti-1333	10	30	and	and	CCONJ
dti-1333	10	31	the	the	DET
dti-1333	10	32	risk	risk	NOUN
dti-1333	10	33	of	of	ADP
dti-1333	10	34	cardiovascular	cardiovascular	ADJ
dti-1333	10	35	disease	disease	NOUN
dti-1333	10	36	.	.	PUNCT
dti-1333	11	1	based	base	VERB
dti-1333	11	2	on	on	ADP
dti-1333	11	3	the	the	DET
dti-1333	11	4	rct	rct	PROPN
dti-1333	11	5	model	model	NOUN
dti-1333	11	6	,	,	PUNCT
dti-1333	11	7	apoa	apoa	PROPN
dti-1333	11	8	-	-	PUNCT
dti-1333	11	9	i	i	PRON
dti-1333	11	10	is	be	AUX
dti-1333	11	11	an	an	DET
dti-1333	11	12	attractive	attractive	ADJ
dti-1333	11	13	target	target	NOUN
dti-1333	11	14	for	for	ADP
dti-1333	11	15	therapeutic	therapeutic	ADJ
dti-1333	11	16	intervention	intervention	NOUN
dti-1333	11	17	.	.	PUNCT
dti-1333	12	1	experimental	experimental	ADJ
dti-1333	12	2	manipulations	manipulation	NOUN
dti-1333	12	3	to	to	PART
dti-1333	12	4	increase	increase	VERB
dti-1333	12	5	production	production	NOUN
dti-1333	12	6	of	of	ADP
dti-1333	12	7	apoa	apoa	NOUN
dti-1333	12	8	-	-	PUNCT
dti-1333	12	9	i	i	PRON
dti-1333	12	10	have	have	AUX
dti-1333	12	11	been	be	AUX
dti-1333	12	12	associated	associate	VERB
dti-1333	12	13	with	with	ADP
dti-1333	12	14	reduced	reduced	ADJ
dti-1333	12	15	atherogenicity	atherogenicity	NOUN
dti-1333	12	16	.	.	PUNCT
dti-1333	13	1	there	there	PRON
dti-1333	13	2	is	be	VERB
dti-1333	13	3	a	a	DET
dti-1333	13	4	continuing	continue	VERB
dti-1333	13	5	need	need	NOUN
dti-1333	13	6	for	for	ADP
dti-1333	13	7	novel	novel	ADJ
dti-1333	13	8	therapies	therapy	NOUN
dti-1333	13	9	that	that	PRON
dti-1333	13	10	increase	increase	VERB
dti-1333	13	11	the	the	DET
dti-1333	13	12	biosynthesis	biosynthesis	NOUN
dti-1333	13	13	of	of	ADP
dti-1333	13	14	hdl	hdl	NOUN
dti-1333	13	15	,	,	PUNCT
dti-1333	13	16	to	to	PART
dti-1333	13	17	inhibit	inhibit	VERB
dti-1333	13	18	the	the	DET
dti-1333	13	19	progression	progression	NOUN
dti-1333	13	20	of	of	ADP
dti-1333	13	21	and	and	CCONJ
dti-1333	13	22	even	even	ADV
dti-1333	13	23	bring	bring	VERB
dti-1333	13	24	about	about	ADP
dti-1333	13	25	regression	regression	NOUN
dti-1333	13	26	of	of	ADP
dti-1333	13	27	atherosclerosis	atherosclerosis	NOUN
dti-1333	13	28	.	.	PUNCT
dti-1333	14	1	small	small	ADJ
dti-1333	14	2	molecule	molecule	NOUN
dti-1333	14	3	compounds	compound	NOUN
dti-1333	14	4	that	that	PRON
dti-1333	14	5	increase	increase	VERB
dti-1333	14	6	the	the	DET
dti-1333	14	7	production	production	NOUN
dti-1333	14	8	of	of	ADP
dti-1333	14	9	endogenous	endogenous	ADJ
dti-1333	14	10	apoa	apoa	NOUN
dti-1333	14	11	-	-	PUNCT
dti-1333	14	12	i	i	PRON
dti-1333	14	13	would	would	AUX
dti-1333	14	14	be	be	AUX
dti-1333	14	15	attractive	attractive	ADJ
dti-1333	14	16	therapeutic	therapeutic	ADJ
dti-1333	14	17	agents	agent	NOUN
dti-1333	14	18	for	for	ADP
dti-1333	14	19	treating	treat	VERB
dti-1333	14	20	dyslipidemias	dyslipidemia	NOUN
dti-1333	14	21	.	.	PUNCT
dti-1333	15	1	keywords	keyword	NOUN
dti-1333	15	2	:	:	PUNCT
dti-1333	15	3	cholesterol	cholesterol	NOUN
dti-1333	15	4	,	,	PUNCT
dti-1333	15	5	apolipoprotein	apolipoprotein	VERB
dti-1333	15	6	a	a	PRON
dti-1333	15	7	-	-	PUNCT
dti-1333	15	8	i	i	NOUN
dti-1333	15	9	(	(	PUNCT
dti-1333	15	10	apoa	apoa	PROPN
dti-1333	15	11	-	-	PUNCT
dti-1333	15	12	i	i	PROPN
dti-1333	15	13	)	)	PUNCT
dti-1333	15	14	,	,	PUNCT
dti-1333	15	15	high	high	ADJ
dti-1333	15	16	-	-	PUNCT
dti-1333	15	17	density	density	NOUN
dti-1333	15	18	lipoprotein	lipoprotein	ADJ
dti-1333	15	19	(	(	PUNCT
dti-1333	15	20	hdl	hdl	NOUN
dti-1333	15	21	)	)	PUNCT
dti-1333	15	22	,	,	PUNCT
dti-1333	15	23	transcription	transcription	NOUN
dti-1333	15	24	,	,	PUNCT
dti-1333	15	25	reverse	reverse	VERB
dti-1333	15	26	cholesterol	cholesterol	NOUN
dti-1333	15	27	transport	transport	NOUN
dti-1333	15	28	(	(	PUNCT
dti-1333	15	29	rct	rct	PROPN
dti-1333	15	30	)	)	PUNCT
dti-1333	15	31	,	,	PUNCT
dti-1333	15	32	atherosclerosis	atherosclerosis	NOUN
dti-1333	15	33	,	,	PUNCT
dti-1333	15	34	dyslipidemia	dyslipidemia	NOUN
dti-1333	15	35	introduction	introduction	NOUN
dti-1333	15	36	because	because	SCONJ
dti-1333	15	37	cholesterol	cholesterol	NOUN
dti-1333	15	38	is	be	AUX
dti-1333	15	39	almost	almost	ADV
dti-1333	15	40	insoluble	insoluble	ADJ
dti-1333	15	41	in	in	ADP
dti-1333	15	42	water	water	NOUN
dti-1333	15	43	,	,	PUNCT
dti-1333	15	44	it	it	PRON
dti-1333	15	45	is	be	AUX
dti-1333	15	46	transported	transport	VERB
dti-1333	15	47	around	around	ADP
dti-1333	15	48	the	the	DET
dti-1333	15	49	body	body	NOUN
dti-1333	15	50	in	in	ADP
dti-1333	15	51	the	the	DET
dti-1333	15	52	form	form	NOUN
dti-1333	15	53	of	of	ADP
dti-1333	15	54	lipoprotein	lipoprotein	ADJ
dti-1333	15	55	(	(	PUNCT
dti-1333	15	56	lipid	lipid	NOUN
dti-1333	15	57	/	/	SYM
dti-1333	15	58	protein	protein	NOUN
dti-1333	15	59	)	)	PUNCT
dti-1333	15	60	complexes	complex	NOUN
dti-1333	15	61	.	.	PUNCT
dti-1333	16	1	the	the	DET
dti-1333	16	2	liver	liver	NOUN
dti-1333	16	3	produces	produce	VERB
dti-1333	16	4	very	very	ADV
dti-1333	16	5	low	low	ADJ
dti-1333	16	6	density	density	NOUN
dti-1333	16	7	lipoproteins	lipoprotein	NOUN
dti-1333	16	8	(	(	PUNCT
dti-1333	16	9	vldl	vldl	NOUN
dti-1333	16	10	)	)	PUNCT
dti-1333	16	11	and	and	CCONJ
dti-1333	16	12	secretes	secrete	VERB
dti-1333	16	13	them	they	PRON
dti-1333	16	14	into	into	ADP
dti-1333	16	15	plasma	plasma	NOUN
dti-1333	16	16	,	,	PUNCT
dti-1333	16	17	where	where	SCONJ
dti-1333	16	18	they	they	PRON
dti-1333	16	19	are	be	AUX
dti-1333	16	20	converted	convert	VERB
dti-1333	16	21	to	to	ADP
dti-1333	16	22	low	low	ADJ
dti-1333	16	23	-	-	PUNCT
dti-1333	16	24	density	density	NOUN
dti-1333	16	25	lipoprotein	lipoprotein	ADJ
dti-1333	16	26	(	(	PUNCT
dti-1333	16	27	ldl	ldl	NOUN
dti-1333	16	28	)	)	PUNCT
dti-1333	16	29	particles	particle	NOUN
dti-1333	16	30	and	and	CCONJ
dti-1333	16	31	non	non	ADJ
dti-1333	16	32	-	-	ADJ
dti-1333	16	33	esterifi	esterifi	ADJ
dti-1333	16	34	ed	ed	NOUN
dti-1333	16	35	fatty	fatty	NOUN
dti-1333	16	36	acids	acid	NOUN
dti-1333	16	37	(	(	PUNCT
dti-1333	16	38	schaefer	schaefer	PROPN
dti-1333	16	39	et	et	PROPN
dti-1333	16	40	al	al	PROPN
dti-1333	16	41	.	.	PROPN
dti-1333	16	42	1978	1978	NUM
dti-1333	16	43	)	)	PUNCT
dti-1333	16	44	.	.	PUNCT
dti-1333	17	1	high	high	ADJ
dti-1333	17	2	-	-	PUNCT
dti-1333	17	3	density	density	NOUN
dti-1333	17	4	lipoprotein	lipoprotein	ADJ
dti-1333	17	5	(	(	PUNCT
dti-1333	17	6	hdl	hdl	NOUN
dti-1333	17	7	)	)	PUNCT
dti-1333	17	8	particles	particle	NOUN
dti-1333	17	9	transport	transport	VERB
dti-1333	17	10	cholesterol	cholesterol	NOUN
dti-1333	17	11	from	from	ADP
dti-1333	17	12	tissues	tissue	NOUN
dti-1333	17	13	back	back	ADV
dti-1333	17	14	to	to	ADP
dti-1333	17	15	the	the	DET
dti-1333	17	16	liver	liver	NOUN
dti-1333	17	17	for	for	ADP
dti-1333	17	18	excretion	excretion	NOUN
dti-1333	17	19	,	,	PUNCT
dti-1333	17	20	as	as	ADP
dti-1333	17	21	fecal	fecal	ADJ
dti-1333	17	22	sterols	sterol	NOUN
dti-1333	17	23	and	and	CCONJ
dti-1333	17	24	bile	bile	NOUN
dti-1333	17	25	acids	acid	NOUN
dti-1333	17	26	.	.	PUNCT
dti-1333	18	1	hdl	hdl	PROPN
dti-1333	18	2	exists	exist	VERB
dti-1333	18	3	primarily	primarily	ADV
dti-1333	18	4	in	in	ADP
dti-1333	18	5	two	two	NUM
dti-1333	18	6	forms	form	NOUN
dti-1333	18	7	,	,	PUNCT
dti-1333	18	8	one	one	NUM
dti-1333	18	9	containing	contain	VERB
dti-1333	18	10	apolipoprotein	apolipoprotein	ADJ
dti-1333	18	11	a	a	PRON
dti-1333	18	12	-	-	PUNCT
dti-1333	18	13	i	i	NOUN
dti-1333	18	14	(	(	PUNCT
dti-1333	18	15	apoa	apoa	NOUN
dti-1333	18	16	-	-	PUNCT
dti-1333	18	17	i	i	PROPN
dti-1333	18	18	)	)	PUNCT
dti-1333	18	19	and	and	CCONJ
dti-1333	18	20	apolipoprotein	apolipoprotein	VERB
dti-1333	18	21	a	a	DET
dti-1333	18	22	-	-	PUNCT
dti-1333	18	23	ii	ii	NOUN
dti-1333	18	24	(	(	PUNCT
dti-1333	18	25	apoa	apoa	PROPN
dti-1333	18	26	-	-	PUNCT
dti-1333	18	27	ii	ii	PROPN
dti-1333	18	28	)	)	PUNCT
dti-1333	18	29	,	,	PUNCT
dti-1333	18	30	and	and	CCONJ
dti-1333	18	31	one	one	NUM
dti-1333	18	32	containing	contain	VERB
dti-1333	18	33	apoa	apoa	NOUN
dti-1333	18	34	-	-	PUNCT
dti-1333	18	35	i	i	PRON
dti-1333	18	36	alone	alone	ADV
dti-1333	18	37	(	(	PUNCT
dti-1333	18	38	schultz	schultz	PROPN
dti-1333	18	39	et	et	PROPN
dti-1333	18	40	al	al	PROPN
dti-1333	18	41	.	.	PROPN
dti-1333	18	42	1993	1993	NUM
dti-1333	18	43	)	)	PUNCT
dti-1333	18	44	.	.	PUNCT
dti-1333	19	1	the	the	DET
dti-1333	19	2	cardioprotective	cardioprotective	ADJ
dti-1333	19	3	effect	effect	NOUN
dti-1333	19	4	is	be	AUX
dti-1333	19	5	largely	largely	ADV
dti-1333	19	6	due	due	ADJ
dti-1333	19	7	to	to	ADP
dti-1333	19	8	apoa	apoa	NOUN
dti-1333	19	9	-	-	PUNCT
dti-1333	19	10	i.	i.	NOUN
dti-1333	20	1	in	in	ADP
dti-1333	20	2	addition	addition	NOUN
dti-1333	20	3	to	to	ADP
dti-1333	20	4	their	their	PRON
dti-1333	20	5	role	role	NOUN
dti-1333	20	6	in	in	ADP
dti-1333	20	7	rct	rct	PROPN
dti-1333	20	8	,	,	PUNCT
dti-1333	20	9	hdl	hdl	PROPN
dti-1333	20	10	particles	particle	NOUN
dti-1333	20	11	have	have	VERB
dti-1333	20	12	anti	anti	ADJ
dti-1333	20	13	-	-	ADJ
dti-1333	20	14	infl	infl	ADJ
dti-1333	20	15	ammatory	ammatory	NOUN
dti-1333	20	16	,	,	PUNCT
dti-1333	20	17	anti	anti	ADJ
dti-1333	20	18	-	-	ADJ
dti-1333	20	19	oxidative	oxidative	ADJ
dti-1333	20	20	,	,	PUNCT
dti-1333	20	21	anti	anti	ADJ
dti-1333	20	22	-	-	ADJ
dti-1333	20	23	apoptotic	apoptotic	ADJ
dti-1333	20	24	,	,	PUNCT
dti-1333	20	25	anti	anti	ADJ
dti-1333	20	26	-	-	ADJ
dti-1333	20	27	thrombotic	thrombotic	ADJ
dti-1333	20	28	,	,	PUNCT
dti-1333	20	29	vasodilatory	vasodilatory	NOUN
dti-1333	20	30	,	,	PUNCT
dti-1333	20	31	and	and	CCONJ
dti-1333	20	32	antiinfective	antiinfective	ADJ
dti-1333	20	33	properties	property	NOUN
dti-1333	20	34	.	.	PUNCT
dti-1333	21	1	the	the	DET
dti-1333	21	2	lipid	lipid	NOUN
dti-1333	21	3	hypothesis	hypothesis	NOUN
dti-1333	21	4	,	,	PUNCT
dti-1333	21	5	proposed	propose	VERB
dti-1333	21	6	more	more	ADJ
dti-1333	21	7	than	than	ADP
dti-1333	21	8	a	a	DET
dti-1333	21	9	century	century	NOUN
dti-1333	21	10	ago	ago	ADV
dti-1333	21	11	,	,	PUNCT
dti-1333	21	12	is	be	AUX
dti-1333	21	13	based	base	VERB
dti-1333	21	14	on	on	ADP
dti-1333	21	15	the	the	DET
dti-1333	21	16	idea	idea	NOUN
dti-1333	21	17	that	that	PRON
dti-1333	21	18	dyslipidemia	dyslipidemia	NOUN
dti-1333	21	19	is	be	AUX
dti-1333	21	20	central	central	ADJ
dti-1333	21	21	to	to	ADP
dti-1333	21	22	atherosclerosis	atherosclerosis	NOUN
dti-1333	21	23	(	(	PUNCT
dti-1333	21	24	steinberg	steinberg	PROPN
dti-1333	21	25	2004	2004	NUM
dti-1333	21	26	,	,	PUNCT
dti-1333	21	27	2005a	2005a	NUM
dti-1333	21	28	,	,	PUNCT
dti-1333	21	29	2005b	2005b	NUM
dti-1333	21	30	,	,	PUNCT
dti-1333	21	31	2006a	2006a	NUM
dti-1333	21	32	,	,	PUNCT
dti-1333	21	33	2006b	2006b	NUM
dti-1333	21	34	)	)	PUNCT
dti-1333	21	35	.	.	PUNCT
dti-1333	22	1	the	the	DET
dti-1333	22	2	validity	validity	NOUN
dti-1333	22	3	of	of	ADP
dti-1333	22	4	the	the	DET
dti-1333	22	5	hypothesis	hypothesis	NOUN
dti-1333	22	6	was	be	AUX
dti-1333	22	7	ultimately	ultimately	ADV
dti-1333	22	8	established	establish	VERB
dti-1333	22	9	by	by	ADP
dti-1333	22	10	major	major	ADJ
dti-1333	22	11	epidemiological	epidemiological	ADJ
dti-1333	22	12	studies	study	NOUN
dti-1333	22	13	,	,	PUNCT
dti-1333	22	14	such	such	ADJ
dti-1333	22	15	as	as	ADP
dti-1333	22	16	the	the	DET
dti-1333	22	17	“	"	PUNCT
dti-1333	22	18	seven	seven	NUM
dti-1333	22	19	countries	country	NOUN
dti-1333	22	20	study	study	VERB
dti-1333	22	21	,	,	PUNCT
dti-1333	22	22	”	"	PUNCT
dti-1333	22	23	which	which	PRON
dti-1333	22	24	,	,	PUNCT
dti-1333	22	25	with	with	ADP
dti-1333	22	26	a	a	DET
dti-1333	22	27	25	25	NUM
dti-1333	22	28	-	-	PUNCT
dti-1333	22	29	year	year	NOUN
dti-1333	22	30	follow	follow	NOUN
dti-1333	22	31	-	-	PUNCT
dti-1333	22	32	up	up	NOUN
dti-1333	22	33	,	,	PUNCT
dti-1333	22	34	found	find	VERB
dti-1333	22	35	that	that	SCONJ
dti-1333	22	36	across	across	ADP
dti-1333	22	37	cultures	culture	NOUN
dti-1333	22	38	,	,	PUNCT
dti-1333	22	39	cholesterol	cholesterol	NOUN
dti-1333	22	40	levels	level	NOUN
dti-1333	22	41	were	be	AUX
dti-1333	22	42	linearly	linearly	ADV
dti-1333	22	43	related	relate	VERB
dti-1333	22	44	to	to	ADP
dti-1333	22	45	coronary	coronary	ADJ
dti-1333	22	46	heart	heart	NOUN
dti-1333	22	47	disease	disease	NOUN
dti-1333	22	48	mortality	mortality	NOUN
dti-1333	22	49	(	(	PUNCT
dti-1333	22	50	verschuren	verschuren	NOUN
dti-1333	22	51	et	et	PROPN
dti-1333	22	52	al	al	PROPN
dti-1333	22	53	.	.	PROPN
dti-1333	22	54	1995	1995	NUM
dti-1333	22	55	)	)	PUNCT
dti-1333	22	56	.	.	PUNCT
dti-1333	23	1	other	other	ADJ
dti-1333	23	2	epidemiological	epidemiological	ADJ
dti-1333	23	3	studies	study	NOUN
dti-1333	23	4	,	,	PUNCT
dti-1333	23	5	including	include	VERB
dti-1333	23	6	the	the	DET
dti-1333	23	7	framingham	framingham	PROPN
dti-1333	23	8	(	(	PUNCT
dti-1333	23	9	gordon	gordon	PROPN
dti-1333	23	10	et	et	PROPN
dti-1333	23	11	al	al	PROPN
dti-1333	23	12	.	.	PROPN
dti-1333	23	13	1977	1977	NUM
dti-1333	23	14	)	)	PUNCT
dti-1333	23	15	and	and	CCONJ
dti-1333	23	16	procam	procam	NOUN
dti-1333	23	17	(	(	PUNCT
dti-1333	23	18	assmann	assmann	PROPN
dti-1333	23	19	et	et	PROPN
dti-1333	23	20	al	al	PROPN
dti-1333	23	21	.	.	PROPN
dti-1333	23	22	1982	1982	NUM
dti-1333	23	23	)	)	PUNCT
dti-1333	23	24	studies	study	NOUN
dti-1333	23	25	,	,	PUNCT
dti-1333	23	26	have	have	AUX
dti-1333	23	27	shown	show	VERB
dti-1333	23	28	an	an	DET
dti-1333	23	29	inverse	inverse	NOUN
dti-1333	23	30	relationship	relationship	NOUN
dti-1333	23	31	between	between	ADP
dti-1333	23	32	blood	blood	NOUN
dti-1333	23	33	levels	level	NOUN
dti-1333	23	34	of	of	ADP
dti-1333	23	35	hdl	hdl	PROPN
dti-1333	23	36	-	-	PUNCT
dti-1333	23	37	c	c	PROPN
dti-1333	23	38	and	and	CCONJ
dti-1333	23	39	the	the	DET
dti-1333	23	40	incidence	incidence	NOUN
dti-1333	23	41	of	of	ADP
dti-1333	23	42	clinically	clinically	ADV
dti-1333	23	43	signifi	signifi	NOUN
dti-1333	23	44	ca	can	AUX
dti-1333	23	45	nt	not	PART
dti-1333	23	46	atherosclerosis	atherosclerosis	NOUN
dti-1333	23	47	(	(	PUNCT
dti-1333	23	48	boden	boden	PROPN
dti-1333	23	49	,	,	PUNCT
dti-1333	23	50	2000	2000	NUM
dti-1333	23	51	)	)	PUNCT
dti-1333	23	52	.	.	PUNCT
dti-1333	24	1	this	this	DET
dti-1333	24	2	inverse	inverse	NOUN
dti-1333	24	3	association	association	NOUN
dti-1333	24	4	between	between	ADP
dti-1333	24	5	hdl	hdl	PROPN
dti-1333	24	6	-	-	PUNCT
dti-1333	24	7	c	c	NOUN
dti-1333	24	8	concentrations	concentration	NOUN
dti-1333	24	9	and	and	CCONJ
dti-1333	24	10	cardiovascular	cardiovascular	ADJ
dti-1333	24	11	risk	risk	NOUN
dti-1333	24	12	is	be	AUX
dti-1333	24	13	apparently	apparently	ADV
dti-1333	24	14	continuous	continuous	ADJ
dti-1333	24	15	;	;	PUNCT
dti-1333	24	16	there	there	PRON
dti-1333	24	17	seems	seem	VERB
dti-1333	24	18	to	to	PART
dti-1333	24	19	be	be	AUX
dti-1333	24	20	no	no	DET
dti-1333	24	21	threshold	threshold	NOUN
dti-1333	24	22	value	value	NOUN
dti-1333	24	23	.	.	PUNCT
dti-1333	25	1	in	in	ADP
dti-1333	25	2	fact	fact	NOUN
dti-1333	25	3	,	,	PUNCT
dti-1333	25	4	each	each	DET
dti-1333	25	5	1	1	NUM
dti-1333	25	6	mg	mg	PROPN
dti-1333	25	7	/	/	SYM
dti-1333	25	8	dl	dl	PROPN
dti-1333	25	9	increment	increment	NOUN
dti-1333	25	10	in	in	ADP
dti-1333	25	11	serum	serum	NOUN
dti-1333	25	12	hdl	hdl	PROPN
dti-1333	25	13	-	-	PUNCT
dti-1333	25	14	c	c	PROPN
dti-1333	25	15	is	be	AUX
dti-1333	25	16	associated	associate	VERB
dti-1333	25	17	with	with	ADP
dti-1333	25	18	a	a	DET
dti-1333	25	19	2%–3	2%–3	NUM
dti-1333	25	20	%	%	NOUN
dti-1333	25	21	decrement	decrement	NOUN
dti-1333	25	22	in	in	ADP
dti-1333	25	23	cardiovascular	cardiovascular	ADJ
dti-1333	25	24	risk	risk	NOUN
dti-1333	25	25	,	,	PUNCT
dti-1333	25	26	while	while	SCONJ
dti-1333	25	27	a	a	DET
dti-1333	25	28	1	1	NUM
dti-1333	25	29	%	%	NOUN
dti-1333	25	30	reduction	reduction	NOUN
dti-1333	25	31	in	in	ADP
dti-1333	25	32	ldl	ldl	NOUN
dti-1333	25	33	-	-	PUNCT
dti-1333	25	34	c	c	PROPN
dti-1333	25	35	decreased	decrease	VERB
dti-1333	25	36	the	the	DET
dti-1333	25	37	risk	risk	NOUN
dti-1333	25	38	of	of	ADP
dti-1333	25	39	coronary	coronary	ADJ
dti-1333	25	40	heart	heart	NOUN
dti-1333	25	41	disease	disease	NOUN
dti-1333	25	42	(	(	PUNCT
dti-1333	25	43	chd	chd	NOUN
dti-1333	25	44	)	)	PUNCT
dti-1333	25	45	by	by	ADP
dti-1333	25	46	1%–2	1%–2	NUM
dti-1333	25	47	%	%	NOUN
dti-1333	25	48	(	(	PUNCT
dti-1333	25	49	boden	boden	PROPN
dti-1333	25	50	,	,	PUNCT
dti-1333	25	51	2000	2000	NUM
dti-1333	25	52	)	)	PUNCT
dti-1333	25	53	.	.	PUNCT
dti-1333	26	1	the	the	DET
dti-1333	26	2	veterans	veterans	PROPN
dti-1333	26	3	affairs	affairs	PROPN
dti-1333	26	4	hdl	hdl	PROPN
dti-1333	26	5	-	-	PUNCT
dti-1333	26	6	c	c	PROPN
dti-1333	26	7	intervention	intervention	NOUN
dti-1333	26	8	trial	trial	NOUN
dti-1333	26	9	(	(	PUNCT
dti-1333	26	10	va	va	NOUN
dti-1333	26	11	-	-	PUNCT
dti-1333	26	12	hit	hit	NOUN
dti-1333	26	13	)	)	PUNCT
dti-1333	26	14	examined	examine	VERB
dti-1333	26	15	the	the	DET
dti-1333	26	16	benefi	benefi	PROPN
dti-1333	26	17	t	t	PROPN
dti-1333	26	18	of	of	ADP
dti-1333	26	19	secondary	secondary	ADJ
dti-1333	26	20	prevention	prevention	NOUN
dti-1333	26	21	in	in	ADP
dti-1333	26	22	patients	patient	NOUN
dti-1333	26	23	with	with	ADP
dti-1333	26	24	low	low	ADJ
dti-1333	26	25	hdl	hdl	PROPN
dti-1333	26	26	-	-	PUNCT
dti-1333	26	27	c	c	NOUN
dti-1333	26	28	levels	level	NOUN
dti-1333	26	29	and	and	CCONJ
dti-1333	26	30	a	a	DET
dti-1333	26	31	history	history	NOUN
dti-1333	26	32	of	of	ADP
dti-1333	26	33	coronary	coronary	ADJ
dti-1333	26	34	artery	artery	NOUN
dti-1333	26	35	disease	disease	NOUN
dti-1333	26	36	(	(	PUNCT
dti-1333	26	37	cad	cad	NOUN
dti-1333	26	38	)	)	PUNCT
dti-1333	26	39	.	.	PUNCT
dti-1333	27	1	in	in	ADP
dti-1333	27	2	patients	patient	NOUN
dti-1333	27	3	with	with	ADP
dti-1333	27	4	existing	exist	VERB
dti-1333	27	5	cad	cad	NOUN
dti-1333	27	6	,	,	PUNCT
dti-1333	27	7	the	the	DET
dti-1333	27	8	only	only	ADJ
dti-1333	27	9	lipid	lipid	NOUN
dti-1333	27	10	abnormality	abnormality	NOUN
dti-1333	27	11	was	be	AUX
dti-1333	27	12	a	a	DET
dti-1333	27	13	low	low	ADJ
dti-1333	27	14	hdl	hdl	NOUN
dti-1333	27	15	-	-	PUNCT
dti-1333	27	16	c	c	NOUN
dti-1333	27	17	level	level	NOUN
dti-1333	27	18	.	.	PUNCT
dti-1333	28	1	in	in	ADP
dti-1333	28	2	the	the	DET
dti-1333	28	3	2,531	2,531	NUM
dti-1333	28	4	men	man	NOUN
dti-1333	28	5	involved	involve	VERB
dti-1333	28	6	,	,	PUNCT
dti-1333	28	7	the	the	DET
dti-1333	28	8	average	average	ADJ
dti-1333	28	9	baseline	baseline	NOUN
dti-1333	28	10	hdl	hdl	PROPN
dti-1333	28	11	was	be	AUX
dti-1333	28	12	32	32	NUM
dti-1333	28	13	mg	mg	PROPN
dti-1333	28	14	/	/	SYM
dti-1333	28	15	dl	dl	PROPN
dti-1333	28	16	,	,	PUNCT
dti-1333	28	17	ldl	ldl	PROPN
dti-1333	28	18	was	be	AUX
dti-1333	28	19	111	111	NUM
dti-1333	28	20	mg	mg	PROPN
dti-1333	28	21	/	/	SYM
dti-1333	28	22	dl	dl	PROPN
dti-1333	28	23	,	,	PUNCT
dti-1333	28	24	and	and	CCONJ
dti-1333	28	25	triglycerides	triglyceride	NOUN
dti-1333	28	26	(	(	PUNCT
dti-1333	28	27	tgs	tgs	NOUN
dti-1333	28	28	)	)	PUNCT
dti-1333	28	29	were	be	AUX
dti-1333	29	1	160	160	NUM
dti-1333	29	2	mg	mg	PROPN
dti-1333	29	3	/	/	SYM
dti-1333	29	4	dl	dl	PROPN
dti-1333	29	5	.	.	PUNCT
dti-1333	29	6	patients	patient	NOUN
dti-1333	29	7	received	receive	VERB
dti-1333	29	8	gemfi	gemfi	ADP
dti-1333	29	9	brozil	brozil	PROPN
dti-1333	29	10	(	(	PUNCT
dti-1333	29	11	1200	1200	NUM
dti-1333	29	12	mg	mg	PROPN
dti-1333	29	13	/	/	SYM
dti-1333	29	14	d	d	NOUN
dti-1333	29	15	)	)	PUNCT
dti-1333	29	16	or	or	CCONJ
dti-1333	29	17	placebo	placebo	NOUN
dti-1333	29	18	and	and	CCONJ
dti-1333	29	19	were	be	AUX
dti-1333	29	20	followed	follow	VERB
dti-1333	29	21	for	for	ADP
dti-1333	29	22	5	5	NUM
dti-1333	29	23	years	year	NOUN
dti-1333	29	24	;	;	PUNCT
dti-1333	29	25	in	in	ADP
dti-1333	29	26	those	those	PRON
dti-1333	29	27	receiving	receive	VERB
dti-1333	29	28	gemfi	gemfi	NOUN
dti-1333	29	29	brozil	brozil	NOUN
dti-1333	29	30	,	,	PUNCT
dti-1333	29	31	hdl	hdl	PROPN
dti-1333	29	32	increased	increase	VERB
dti-1333	29	33	by	by	ADP
dti-1333	29	34	6	6	NUM
dti-1333	29	35	%	%	NOUN
dti-1333	29	36	and	and	CCONJ
dti-1333	29	37	triglycerides	triglyceride	NOUN
dti-1333	29	38	decreased	decrease	VERB
dti-1333	29	39	by	by	ADP
dti-1333	29	40	31	31	NUM
dti-1333	29	41	%	%	NOUN
dti-1333	29	42	,	,	PUNCT
dti-1333	29	43	with	with	SCONJ
dti-1333	29	44	no	no	DET
dti-1333	29	45	signifi	signifi	NOUN
dti-1333	29	46	ca	can	AUX
dti-1333	29	47	nt	not	PART
dti-1333	29	48	change	change	VERB
dti-1333	29	49	in	in	ADP
dti-1333	29	50	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN
dti-1333	29	51	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN
dti-1333	29	52	46	46	NUM
dti-1333	29	53	brown	brown	ADJ
dti-1333	29	54	and	and	CCONJ
dti-1333	29	55	chiacchia	chiacchia	PROPN
dti-1333	29	56	drug	drug	NOUN
dti-1333	29	57	target	target	NOUN
dti-1333	29	58	insights	insight	NOUN
dti-1333	29	59	2008:3	2008:3	NUM
dti-1333	29	60	ldl	ldl	NOUN
dti-1333	29	61	-	-	PUNCT
dti-1333	29	62	c	c	NOUN
dti-1333	29	63	,	,	PUNCT
dti-1333	29	64	versus	versus	ADP
dti-1333	29	65	the	the	DET
dti-1333	29	66	placebo	placebo	NOUN
dti-1333	29	67	.	.	PUNCT
dti-1333	30	1	coronary	coronary	ADJ
dti-1333	30	2	events	event	NOUN
dti-1333	30	3	were	be	AUX
dti-1333	30	4	reduced	reduce	VERB
dti-1333	30	5	by	by	ADP
dti-1333	30	6	22	22	NUM
dti-1333	30	7	%	%	NOUN
dti-1333	30	8	in	in	ADP
dti-1333	30	9	the	the	DET
dti-1333	30	10	gemfi	gemfi	NOUN
dti-1333	30	11	brozil	brozil	PROPN
dti-1333	30	12	group	group	NOUN
dti-1333	30	13	(	(	PUNCT
dti-1333	30	14	robins	robin	NOUN
dti-1333	30	15	et	et	PROPN
dti-1333	30	16	al	al	PROPN
dti-1333	30	17	.	.	PROPN
dti-1333	30	18	2001	2001	NUM
dti-1333	30	19	)	)	PUNCT
dti-1333	30	20	.	.	PUNCT
dti-1333	31	1	the	the	DET
dti-1333	31	2	air	air	NOUN
dti-1333	31	3	force	force	PROPN
dti-1333	31	4	/	/	SYM
dti-1333	31	5	texas	texas	PROPN
dti-1333	31	6	coronary	coronary	ADJ
dti-1333	31	7	atherosclerosis	atherosclerosis	NOUN
dti-1333	31	8	prevention	prevention	NOUN
dti-1333	31	9	study	study	NOUN
dti-1333	31	10	demonstrated	demonstrate	VERB
dti-1333	31	11	an	an	DET
dti-1333	31	12	association	association	NOUN
dti-1333	31	13	between	between	ADP
dti-1333	31	14	hdl	hdl	PROPN
dti-1333	31	15	-	-	PUNCT
dti-1333	31	16	c	c	PROPN
dti-1333	31	17	levels	level	NOUN
dti-1333	31	18	and	and	CCONJ
dti-1333	31	19	primary	primary	ADJ
dti-1333	31	20	prevention	prevention	NOUN
dti-1333	31	21	of	of	ADP
dti-1333	31	22	cad	cad	PROPN
dti-1333	31	23	.	.	PUNCT
dti-1333	32	1	participants	participant	NOUN
dti-1333	32	2	(	(	PUNCT
dti-1333	32	3	men	man	NOUN
dti-1333	32	4	aged	age	VERB
dti-1333	32	5	45–73	45–73	NUM
dti-1333	32	6	and	and	CCONJ
dti-1333	32	7	postmenopausal	postmenopausal	ADJ
dti-1333	32	8	women	woman	NOUN
dti-1333	32	9	aged	age	VERB
dti-1333	32	10	55–73	55–73	NUM
dti-1333	32	11	)	)	PUNCT
dti-1333	32	12	had	have	VERB
dti-1333	32	13	normal	normal	ADJ
dti-1333	32	14	levels	level	NOUN
dti-1333	32	15	of	of	ADP
dti-1333	32	16	total	total	ADJ
dti-1333	32	17	and	and	CCONJ
dti-1333	32	18	ldl	ldl	NOUN
dti-1333	32	19	-	-	PUNCT
dti-1333	32	20	c	c	NOUN
dti-1333	32	21	,	,	PUNCT
dti-1333	32	22	but	but	CCONJ
dti-1333	32	23	low	low	ADJ
dti-1333	32	24	hdl	hdl	PROPN
dti-1333	32	25	-	-	PUNCT
dti-1333	32	26	c	c	NOUN
dti-1333	32	27	;	;	PUNCT
dti-1333	32	28	they	they	PRON
dti-1333	32	29	received	receive	VERB
dti-1333	32	30	lovastatin	lovastatin	NOUN
dti-1333	32	31	(	(	PUNCT
dti-1333	32	32	20–40	20–40	NUM
dti-1333	32	33	mg	mg	PROPN
dti-1333	32	34	daily	daily	ADV
dti-1333	32	35	)	)	PUNCT
dti-1333	32	36	or	or	CCONJ
dti-1333	32	37	placebo	placebo	NOUN
dti-1333	32	38	.	.	PUNCT
dti-1333	33	1	lovastatin	lovastatin	PROPN
dti-1333	33	2	increased	increase	VERB
dti-1333	33	3	hdl	hdl	NOUN
dti-1333	33	4	by	by	ADP
dti-1333	33	5	6	6	NUM
dti-1333	33	6	%	%	NOUN
dti-1333	33	7	,	,	PUNCT
dti-1333	33	8	reduced	reduce	VERB
dti-1333	33	9	ldl	ldl	NOUN
dti-1333	33	10	by	by	ADP
dti-1333	33	11	25	25	NUM
dti-1333	33	12	%	%	NOUN
dti-1333	33	13	,	,	PUNCT
dti-1333	33	14	and	and	CCONJ
dti-1333	33	15	reduced	reduce	VERB
dti-1333	33	16	cardiac	cardiac	ADJ
dti-1333	33	17	events	event	NOUN
dti-1333	33	18	by	by	ADP
dti-1333	33	19	37	37	NUM
dti-1333	33	20	%	%	NOUN
dti-1333	33	21	,	,	PUNCT
dti-1333	33	22	versus	versus	ADP
dti-1333	33	23	placebo	placebo	NOUN
dti-1333	33	24	(	(	PUNCT
dti-1333	33	25	downs	down	NOUN
dti-1333	33	26	et	et	PROPN
dti-1333	33	27	al	al	PROPN
dti-1333	33	28	.	.	PROPN
dti-1333	33	29	1998	1998	NUM
dti-1333	33	30	)	)	PUNCT
dti-1333	33	31	.	.	PUNCT
dti-1333	34	1	the	the	DET
dti-1333	34	2	swedish	swedish	ADJ
dti-1333	34	3	prospective	prospective	ADJ
dti-1333	34	4	population	population	NOUN
dti-1333	34	5	study	study	NOUN
dti-1333	34	6	,	,	PUNCT
dti-1333	34	7	amoris	amoris	PROPN
dti-1333	34	8	,	,	PUNCT
dti-1333	34	9	followed	follow	VERB
dti-1333	34	10	175,000	175,000	NUM
dti-1333	34	11	men	man	NOUN
dti-1333	34	12	and	and	CCONJ
dti-1333	34	13	women	woman	NOUN
dti-1333	34	14	for	for	ADP
dti-1333	34	15	6	6	NUM
dti-1333	34	16	years	year	NOUN
dti-1333	34	17	and	and	CCONJ
dti-1333	34	18	demonstrated	demonstrate	VERB
dti-1333	34	19	apoa	apoa	NOUN
dti-1333	34	20	-	-	PUNCT
dti-1333	34	21	i	i	PRON
dti-1333	34	22	to	to	PART
dti-1333	34	23	be	be	AUX
dti-1333	34	24	the	the	DET
dti-1333	34	25	most	most	ADV
dti-1333	34	26	potent	potent	ADJ
dti-1333	34	27	protective	protective	ADJ
dti-1333	34	28	factor	factor	NOUN
dti-1333	34	29	against	against	ADP
dti-1333	34	30	fatal	fatal	ADJ
dti-1333	34	31	myocardial	myocardial	ADJ
dti-1333	34	32	infarction	infarction	NOUN
dti-1333	34	33	(	(	PUNCT
dti-1333	34	34	walldius	walldius	NOUN
dti-1333	34	35	et	et	PROPN
dti-1333	34	36	al	al	PROPN
dti-1333	34	37	.	.	PROPN
dti-1333	34	38	2001	2001	NUM
dti-1333	34	39	)	)	PUNCT
dti-1333	34	40	.	.	PUNCT
dti-1333	35	1	the	the	DET
dti-1333	35	2	interheart	interheart	NOUN
dti-1333	35	3	study	study	NOUN
dti-1333	35	4	,	,	PUNCT
dti-1333	35	5	an	an	DET
dti-1333	35	6	international	international	ADJ
dti-1333	35	7	case	case	NOUN
dti-1333	35	8	control	control	NOUN
dti-1333	35	9	study	study	NOUN
dti-1333	35	10	comparing	compare	VERB
dti-1333	35	11	myocardial	myocardial	ADJ
dti-1333	35	12	infarction	infarction	NOUN
dti-1333	35	13	survivors	survivor	NOUN
dti-1333	35	14	with	with	ADP
dti-1333	35	15	ageand	ageand	NOUN
dti-1333	35	16	gender	gender	NOUN
dti-1333	35	17	-	-	PUNCT
dti-1333	35	18	matched	match	VERB
dti-1333	35	19	controls	control	NOUN
dti-1333	35	20	,	,	PUNCT
dti-1333	35	21	showed	show	VERB
dti-1333	35	22	the	the	DET
dti-1333	35	23	apoa	apoa	NOUN
dti-1333	35	24	-	-	PUNCT
dti-1333	35	25	i	i	PROPN
dti-1333	35	26	/	/	SYM
dti-1333	35	27	apob	apob	ADJ
dti-1333	35	28	ratio	ratio	NOUN
dti-1333	35	29	to	to	PART
dti-1333	35	30	be	be	AUX
dti-1333	35	31	the	the	DET
dti-1333	35	32	strongest	strong	ADJ
dti-1333	35	33	modifi	modifi	NOUN
dti-1333	35	34	able	able	ADJ
dti-1333	35	35	protective	protective	ADJ
dti-1333	35	36	factor	factor	NOUN
dti-1333	35	37	(	(	PUNCT
dti-1333	35	38	yusuf	yusuf	PROPN
dti-1333	35	39	et	et	PROPN
dti-1333	35	40	al	al	PROPN
dti-1333	35	41	.	.	PROPN
dti-1333	35	42	2004	2004	NUM
dti-1333	35	43	)	)	PUNCT
dti-1333	35	44	.	.	PUNCT
dti-1333	36	1	reverse	reverse	VERB
dti-1333	36	2	cholesterol	cholesterol	NOUN
dti-1333	36	3	transport	transport	NOUN
dti-1333	36	4	(	(	PUNCT
dti-1333	36	5	rct	rct	PROPN
dti-1333	36	6	)	)	PUNCT
dti-1333	36	7	while	while	SCONJ
dti-1333	36	8	the	the	DET
dti-1333	36	9	mechanisms	mechanism	NOUN
dti-1333	36	10	of	of	ADP
dti-1333	36	11	the	the	DET
dti-1333	36	12	benefi	benefi	PROPN
dti-1333	36	13	cial	cial	ADJ
dti-1333	36	14	effects	effect	NOUN
dti-1333	36	15	of	of	ADP
dti-1333	36	16	hdl	hdl	NOUN
dti-1333	36	17	in	in	ADP
dti-1333	36	18	altering	alter	VERB
dti-1333	36	19	atherosclerotic	atherosclerotic	ADJ
dti-1333	36	20	disease	disease	NOUN
dti-1333	36	21	are	be	AUX
dti-1333	36	22	not	not	PART
dti-1333	36	23	completely	completely	ADV
dti-1333	36	24	understood	understand	VERB
dti-1333	36	25	,	,	PUNCT
dti-1333	36	26	it	it	PRON
dti-1333	36	27	is	be	AUX
dti-1333	36	28	believed	believe	VERB
dti-1333	36	29	that	that	SCONJ
dti-1333	36	30	elevated	elevated	ADJ
dti-1333	36	31	levels	level	NOUN
dti-1333	36	32	of	of	ADP
dti-1333	36	33	hdl	hdl	PROPN
dti-1333	36	34	enhance	enhance	VERB
dti-1333	36	35	the	the	DET
dti-1333	36	36	efflux	efflux	NOUN
dti-1333	36	37	of	of	ADP
dti-1333	36	38	cholesterol	cholesterol	NOUN
dti-1333	36	39	from	from	ADP
dti-1333	36	40	arterial	arterial	ADJ
dti-1333	36	41	walls	wall	NOUN
dti-1333	36	42	,	,	PUNCT
dti-1333	36	43	increasing	increase	VERB
dti-1333	36	44	transport	transport	NOUN
dti-1333	36	45	of	of	ADP
dti-1333	36	46	cholesterol	cholesterol	NOUN
dti-1333	36	47	from	from	ADP
dti-1333	36	48	arteries	artery	NOUN
dti-1333	36	49	to	to	ADP
dti-1333	36	50	the	the	DET
dti-1333	36	51	liver	liver	NOUN
dti-1333	36	52	for	for	ADP
dti-1333	36	53	excretion	excretion	NOUN
dti-1333	36	54	.	.	PUNCT
dti-1333	37	1	increased	increase	VERB
dti-1333	37	2	apoa	apoa	NOUN
dti-1333	37	3	-	-	PUNCT
dti-1333	37	4	i	i	PRON
dti-1333	37	5	increases	increase	VERB
dti-1333	37	6	paraoxonase	paraoxonase	NOUN
dti-1333	37	7	activity	activity	NOUN
dti-1333	37	8	,	,	PUNCT
dti-1333	37	9	and	and	CCONJ
dti-1333	37	10	enhances	enhance	VERB
dti-1333	37	11	anticoagulant	anticoagulant	NOUN
dti-1333	37	12	and	and	CCONJ
dti-1333	37	13	anti	anti	ADJ
dti-1333	37	14	-	-	ADJ
dti-1333	37	15	infl	infl	ADJ
dti-1333	37	16	ammatory	ammatory	NOUN
dti-1333	37	17	activities	activity	NOUN
dti-1333	37	18	.	.	PUNCT
dti-1333	38	1	hdl	hdl	PROPN
dti-1333	38	2	also	also	ADV
dti-1333	38	3	promotes	promote	VERB
dti-1333	38	4	fi	fi	NOUN
dti-1333	38	5	brinolysis	brinolysis	NOUN
dti-1333	38	6	.	.	PUNCT
dti-1333	39	1	additionally	additionally	ADV
dti-1333	39	2	,	,	PUNCT
dti-1333	39	3	hdl	hdl	PROPN
dti-1333	39	4	particles	particle	NOUN
dti-1333	39	5	protect	protect	VERB
dti-1333	39	6	against	against	ADP
dti-1333	39	7	ldl	ldl	NOUN
dti-1333	39	8	oxidation	oxidation	NOUN
dti-1333	39	9	,	,	PUNCT
dti-1333	39	10	a	a	DET
dti-1333	39	11	key	key	ADJ
dti-1333	39	12	step	step	NOUN
dti-1333	39	13	in	in	ADP
dti-1333	39	14	promoting	promote	VERB
dti-1333	39	15	cholesterol	cholesterol	NOUN
dti-1333	39	16	uptake	uptake	NOUN
dti-1333	39	17	by	by	ADP
dti-1333	39	18	arterial	arterial	ADJ
dti-1333	39	19	macrophages	macrophage	NOUN
dti-1333	39	20	.	.	PUNCT
dti-1333	40	1	the	the	DET
dti-1333	40	2	major	major	ADJ
dti-1333	40	3	steps	step	NOUN
dti-1333	40	4	in	in	ADP
dti-1333	40	5	the	the	DET
dti-1333	40	6	reverse	reverse	ADJ
dti-1333	40	7	cholesterol	cholesterol	NOUN
dti-1333	40	8	transport	transport	NOUN
dti-1333	40	9	(	(	PUNCT
dti-1333	40	10	rct	rct	PROPN
dti-1333	40	11	)	)	PUNCT
dti-1333	40	12	pathway	pathway	NOUN
dti-1333	40	13	are	be	AUX
dti-1333	40	14	the	the	DET
dti-1333	40	15	active	active	ADJ
dti-1333	40	16	effl	effl	NOUN
dti-1333	40	17	ux	ux	PROPN
dti-1333	40	18	of	of	ADP
dti-1333	40	19	cholesterol	cholesterol	NOUN
dti-1333	40	20	and	and	CCONJ
dti-1333	40	21	phospholipids	phospholipid	NOUN
dti-1333	40	22	from	from	ADP
dti-1333	40	23	cells	cell	NOUN
dti-1333	40	24	by	by	ADP
dti-1333	40	25	atp	atp	NOUN
dti-1333	40	26	-	-	PUNCT
dti-1333	40	27	binding	bind	VERB
dti-1333	40	28	cassette	cassette	NOUN
dti-1333	40	29	transporter	transporter	NOUN
dti-1333	40	30	a1	a1	NOUN
dti-1333	40	31	(	(	PUNCT
dti-1333	40	32	abca1	abca1	NOUN
dti-1333	40	33	)	)	PUNCT
dti-1333	40	34	,	,	PUNCT
dti-1333	40	35	the	the	DET
dti-1333	40	36	binding	binding	NOUN
dti-1333	40	37	of	of	ADP
dti-1333	40	38	cholesterol	cholesterol	NOUN
dti-1333	40	39	to	to	ADP
dti-1333	40	40	apolipoproteins	apolipoprotein	NOUN
dti-1333	40	41	,	,	PUNCT
dti-1333	40	42	forming	form	VERB
dti-1333	40	43	pre	pre	NOUN
dti-1333	40	44	-	-	ADJ
dti-1333	40	45	β	β	X
dti-1333	40	46	hdl	hdl	PROPN
dti-1333	40	47	,	,	PUNCT
dti-1333	40	48	the	the	DET
dti-1333	40	49	esterifi	esterifi	NOUN
dti-1333	40	50	cation	cation	NOUN
dti-1333	40	51	of	of	ADP
dti-1333	40	52	hdl	hdl	PROPN
dti-1333	40	53	-	-	PUNCT
dti-1333	40	54	bound	bind	VERB
dti-1333	40	55	cholesterol	cholesterol	NOUN
dti-1333	40	56	by	by	ADP
dti-1333	40	57	lecithin	lecithin	NOUN
dti-1333	40	58	cholesterol	cholesterol	NOUN
dti-1333	40	59	acyl	acyl	NOUN
dti-1333	40	60	transferase	transferase	NOUN
dti-1333	40	61	(	(	PUNCT
dti-1333	40	62	lcat	lcat	ADJ
dti-1333	40	63	;	;	PUNCT
dti-1333	40	64	the	the	DET
dti-1333	40	65	resulting	result	VERB
dti-1333	40	66	cholesteryl	cholesteryl	NOUN
dti-1333	40	67	esters	ester	NOUN
dti-1333	40	68	(	(	PUNCT
dti-1333	40	69	ces	ce	NOUN
dti-1333	40	70	)	)	PUNCT
dti-1333	40	71	are	be	AUX
dti-1333	40	72	the	the	DET
dti-1333	40	73	core	core	ADJ
dti-1333	40	74	lipids	lipid	NOUN
dti-1333	40	75	of	of	ADP
dti-1333	40	76	hdl	hdl	PROPN
dti-1333	40	77	)	)	PUNCT
dti-1333	40	78	,	,	PUNCT
dti-1333	40	79	cetp	cetp	NOUN
dti-1333	40	80	-	-	PUNCT
dti-1333	40	81	mediated	mediate	VERB
dti-1333	40	82	exchange	exchange	NOUN
dti-1333	40	83	of	of	ADP
dti-1333	40	84	ces	ce	NOUN
dti-1333	40	85	and	and	CCONJ
dti-1333	40	86	tgs	tgs	PROPN
dti-1333	40	87	between	between	ADP
dti-1333	40	88	hdl	hdl	PROPN
dti-1333	40	89	and	and	CCONJ
dti-1333	40	90	apo	apo	PROPN
dti-1333	40	91	b	b	X
dti-1333	40	92	-	-	PUNCT
dti-1333	40	93	containing	contain	VERB
dti-1333	40	94	particles	particle	NOUN
dti-1333	40	95	,	,	PUNCT
dti-1333	40	96	and	and	CCONJ
dti-1333	40	97	hepatic	hepatic	ADJ
dti-1333	40	98	lipase	lipase	NOUN
dti-1333	40	99	(	(	PUNCT
dti-1333	40	100	hl)-mediated	hl)-mediate	VERB
dti-1333	40	101	uptake	uptake	NOUN
dti-1333	40	102	of	of	ADP
dti-1333	40	103	cholesterol	cholesterol	NOUN
dti-1333	40	104	and	and	CCONJ
dti-1333	40	105	tgs	tgs	PROPN
dti-1333	40	106	by	by	ADP
dti-1333	40	107	the	the	DET
dti-1333	40	108	liver	liver	NOUN
dti-1333	40	109	(	(	PUNCT
dti-1333	40	110	von	von	PROPN
dti-1333	40	111	eckardstein	eckardstein	NOUN
dti-1333	40	112	and	and	CCONJ
dti-1333	40	113	assmann	assmann	PROPN
dti-1333	40	114	,	,	PUNCT
dti-1333	40	115	1998	1998	NUM
dti-1333	40	116	;	;	PUNCT
dti-1333	40	117	see	see	VERB
dti-1333	40	118	fig	fig	NOUN
dti-1333	40	119	.	.	PUNCT
dti-1333	41	1	1	1	NUM
dti-1333	41	2	)	)	PUNCT
dti-1333	41	3	.	.	PUNCT
dti-1333	42	1	this	this	DET
dti-1333	42	2	rct	rct	PROPN
dti-1333	42	3	model	model	NOUN
dti-1333	42	4	is	be	AUX
dti-1333	42	5	used	use	VERB
dti-1333	42	6	to	to	PART
dti-1333	42	7	explain	explain	VERB
dti-1333	42	8	both	both	DET
dti-1333	42	9	hdl	hdl	PROPN
dti-1333	42	10	’s	’s	PART
dti-1333	42	11	role	role	NOUN
dti-1333	42	12	in	in	ADP
dti-1333	42	13	lipid	lipid	ADJ
dti-1333	42	14	metabolism	metabolism	NOUN
dti-1333	42	15	and	and	CCONJ
dti-1333	42	16	the	the	DET
dti-1333	42	17	inverse	inverse	NOUN
dti-1333	42	18	association	association	NOUN
dti-1333	42	19	between	between	ADP
dti-1333	42	20	hdl	hdl	PROPN
dti-1333	42	21	-	-	PUNCT
dti-1333	42	22	c	c	PROPN
dti-1333	42	23	plasma	plasma	NOUN
dti-1333	42	24	concentrations	concentration	NOUN
dti-1333	42	25	and	and	CCONJ
dti-1333	42	26	cardiovascular	cardiovascular	ADJ
dti-1333	42	27	disease	disease	NOUN
dti-1333	42	28	risk	risk	NOUN
dti-1333	42	29	.	.	PUNCT
dti-1333	43	1	the	the	DET
dti-1333	43	2	effects	effect	NOUN
dti-1333	43	3	of	of	ADP
dti-1333	43	4	mutations	mutation	NOUN
dti-1333	43	5	in	in	ADP
dti-1333	43	6	the	the	DET
dti-1333	43	7	various	various	ADJ
dti-1333	43	8	proteins	protein	NOUN
dti-1333	43	9	and	and	CCONJ
dti-1333	43	10	enzymes	enzyme	NOUN
dti-1333	43	11	of	of	ADP
dti-1333	43	12	the	the	DET
dti-1333	43	13	rct	rct	PROPN
dti-1333	43	14	pathway	pathway	NOUN
dti-1333	43	15	have	have	AUX
dti-1333	43	16	helped	help	VERB
dti-1333	43	17	in	in	ADP
dti-1333	43	18	our	our	PRON
dti-1333	43	19	understanding	understanding	NOUN
dti-1333	43	20	of	of	ADP
dti-1333	43	21	cholesterol	cholesterol	NOUN
dti-1333	43	22	metabolism	metabolism	NOUN
dti-1333	43	23	.	.	PUNCT
dti-1333	44	1	based	base	VERB
dti-1333	44	2	on	on	ADP
dti-1333	44	3	the	the	DET
dti-1333	44	4	rct	rct	PROPN
dti-1333	44	5	model	model	NOUN
dti-1333	44	6	,	,	PUNCT
dti-1333	44	7	apoa	apoa	PROPN
dti-1333	44	8	-	-	PUNCT
dti-1333	44	9	i	i	PRON
dti-1333	44	10	is	be	AUX
dti-1333	44	11	an	an	DET
dti-1333	44	12	attractive	attractive	ADJ
dti-1333	44	13	target	target	NOUN
dti-1333	44	14	for	for	ADP
dti-1333	44	15	therapeutic	therapeutic	ADJ
dti-1333	44	16	intervention	intervention	NOUN
dti-1333	44	17	.	.	PUNCT
dti-1333	45	1	experimental	experimental	ADJ
dti-1333	45	2	manipulations	manipulation	NOUN
dti-1333	45	3	that	that	PRON
dti-1333	45	4	increase	increase	VERB
dti-1333	45	5	production	production	NOUN
dti-1333	45	6	of	of	ADP
dti-1333	45	7	apoa	apoa	NOUN
dti-1333	45	8	-	-	PUNCT
dti-1333	45	9	i	i	PRON
dti-1333	45	10	have	have	AUX
dti-1333	45	11	been	be	AUX
dti-1333	45	12	associated	associate	VERB
dti-1333	45	13	with	with	ADP
dti-1333	45	14	reduced	reduced	ADJ
dti-1333	45	15	atherogenicity	atherogenicity	NOUN
dti-1333	45	16	.	.	PUNCT
dti-1333	46	1	human	human	ADJ
dti-1333	46	2	apoa	apoa	PROPN
dti-1333	46	3	-	-	PUNCT
dti-1333	46	4	i	i	PRON
dti-1333	46	5	is	be	AUX
dti-1333	46	6	protective	protective	ADJ
dti-1333	46	7	in	in	ADP
dti-1333	46	8	transgenic	transgenic	NOUN
dti-1333	46	9	animal	animal	NOUN
dti-1333	46	10	models	model	NOUN
dti-1333	46	11	(	(	PUNCT
dti-1333	46	12	shah	shah	PROPN
dti-1333	46	13	et	et	PROPN
dti-1333	46	14	al	al	PROPN
dti-1333	46	15	.	.	PROPN
dti-1333	46	16	1998	1998	NUM
dti-1333	46	17	;	;	PUNCT
dti-1333	46	18	rubin	rubin	PROPN
dti-1333	46	19	et	et	PROPN
dti-1333	46	20	al	al	PROPN
dti-1333	46	21	.	.	PROPN
dti-1333	46	22	1991	1991	NUM
dti-1333	46	23	)	)	PUNCT
dti-1333	46	24	,	,	PUNCT
dti-1333	46	25	and	and	CCONJ
dti-1333	46	26	infusion	infusion	NOUN
dti-1333	46	27	of	of	ADP
dti-1333	46	28	apoa	apoa	NOUN
dti-1333	46	29	-	-	PUNCT
dti-1333	46	30	imilano	imilano	PROPN
dti-1333	46	31	prevents	prevent	VERB
dti-1333	46	32	atherosclerotic	atherosclerotic	ADJ
dti-1333	46	33	lesions	lesion	NOUN
dti-1333	46	34	and	and	CCONJ
dti-1333	46	35	leads	lead	VERB
dti-1333	46	36	to	to	ADP
dti-1333	46	37	regression	regression	NOUN
dti-1333	46	38	of	of	ADP
dti-1333	46	39	atherosclerotic	atherosclerotic	ADJ
dti-1333	46	40	plaques	plaque	NOUN
dti-1333	46	41	in	in	ADP
dti-1333	46	42	human	human	ADJ
dti-1333	46	43	patients	patient	NOUN
dti-1333	46	44	(	(	PUNCT
dti-1333	46	45	below	below	ADV
dti-1333	46	46	)	)	PUNCT
dti-1333	46	47	.	.	PUNCT
dti-1333	47	1	small	small	ADJ
dti-1333	47	2	-	-	PUNCT
dti-1333	47	3	molecule	molecule	NOUN
dti-1333	47	4	compounds	compound	NOUN
dti-1333	47	5	that	that	PRON
dti-1333	47	6	increase	increase	VERB
dti-1333	47	7	the	the	DET
dti-1333	47	8	production	production	NOUN
dti-1333	47	9	of	of	ADP
dti-1333	47	10	endogenous	endogenous	ADJ
dti-1333	47	11	apoa	apoa	NOUN
dti-1333	47	12	-	-	PUNCT
dti-1333	47	13	i	i	PRON
dti-1333	47	14	would	would	AUX
dti-1333	47	15	be	be	AUX
dti-1333	47	16	attractive	attractive	ADJ
dti-1333	47	17	therapeutic	therapeutic	ADJ
dti-1333	47	18	agents	agent	NOUN
dti-1333	47	19	for	for	ADP
dti-1333	47	20	treating	treat	VERB
dti-1333	47	21	dyslipidemias	dyslipidemia	NOUN
dti-1333	47	22	.	.	PUNCT
dti-1333	48	1	familial	familial	ADJ
dti-1333	48	2	hdl	hdl	NOUN
dti-1333	48	3	abnormalities	abnormality	NOUN
dti-1333	48	4	as	as	ADP
dti-1333	48	5	familial	familial	ADJ
dti-1333	48	6	hdl	hdl	PROPN
dti-1333	48	7	-	-	PUNCT
dti-1333	48	8	c	c	PROPN
dti-1333	48	9	defi	defi	NOUN
dti-1333	48	10	ciency	ciency	NOUN
dti-1333	48	11	is	be	AUX
dti-1333	48	12	often	often	ADV
dti-1333	48	13	associated	associate	VERB
dti-1333	48	14	with	with	ADP
dti-1333	48	15	family	family	NOUN
dti-1333	48	16	histories	history	NOUN
dti-1333	48	17	of	of	ADP
dti-1333	48	18	premature	premature	PROPN
dti-1333	48	19	cad	cad	NOUN
dti-1333	48	20	,	,	PUNCT
dti-1333	48	21	much	much	ADJ
dti-1333	48	22	effort	effort	NOUN
dti-1333	48	23	has	have	AUX
dti-1333	48	24	been	be	AUX
dti-1333	48	25	directed	direct	VERB
dti-1333	48	26	to	to	ADP
dti-1333	48	27	understanding	understand	VERB
dti-1333	48	28	the	the	DET
dti-1333	48	29	molecular	molecular	ADJ
dti-1333	48	30	defect(s	defect(s	NOUN
dti-1333	48	31	)	)	PUNCT
dti-1333	49	1	involved	involve	VERB
dti-1333	49	2	(	(	PUNCT
dti-1333	49	3	hovingh	hovingh	ADV
dti-1333	49	4	et	et	PROPN
dti-1333	49	5	al	al	PROPN
dti-1333	49	6	.	.	PROPN
dti-1333	49	7	2005	2005	NUM
dti-1333	49	8	;	;	PUNCT
dti-1333	49	9	von	von	PROPN
dti-1333	49	10	eckardstein	eckardstein	PROPN
dti-1333	49	11	and	and	CCONJ
dti-1333	49	12	assmann	assmann	PROPN
dti-1333	49	13	,	,	PUNCT
dti-1333	49	14	1998	1998	NUM
dti-1333	49	15	;	;	PUNCT
dti-1333	49	16	calabresi	calabresi	NOUN
dti-1333	49	17	and	and	CCONJ
dti-1333	49	18	franceschini	franceschini	NOUN
dti-1333	49	19	,	,	PUNCT
dti-1333	49	20	1997	1997	NUM
dti-1333	49	21	)	)	PUNCT
dti-1333	49	22	.	.	PUNCT
dti-1333	50	1	increased	increase	VERB
dti-1333	50	2	hdl	hdl	PROPN
dti-1333	50	3	-	-	PUNCT
dti-1333	50	4	c	c	NOUN
dti-1333	50	5	concentrations	concentration	NOUN
dti-1333	50	6	are	be	AUX
dti-1333	50	7	generally	generally	ADV
dti-1333	50	8	accepted	accept	VERB
dti-1333	50	9	to	to	PART
dti-1333	50	10	be	be	AUX
dti-1333	50	11	protective	protective	ADJ
dti-1333	50	12	against	against	ADP
dti-1333	50	13	the	the	DET
dti-1333	50	14	development	development	NOUN
dti-1333	50	15	of	of	ADP
dti-1333	50	16	atherosclerosis	atherosclerosis	NOUN
dti-1333	50	17	and	and	CCONJ
dti-1333	50	18	cad	cad	NOUN
dti-1333	50	19	,	,	PUNCT
dti-1333	50	20	but	but	CCONJ
dti-1333	50	21	studies	study	NOUN
dti-1333	50	22	have	have	AUX
dti-1333	50	23	suggested	suggest	VERB
dti-1333	50	24	that	that	SCONJ
dti-1333	50	25	the	the	DET
dti-1333	50	26	underlying	underlie	VERB
dti-1333	50	27	cause	cause	NOUN
dti-1333	50	28	of	of	ADP
dti-1333	50	29	the	the	DET
dti-1333	50	30	increased	increase	VERB
dti-1333	50	31	hdl	hdl	PROPN
dti-1333	50	32	-	-	PUNCT
dti-1333	50	33	c	c	PROPN
dti-1333	50	34	may	may	AUX
dti-1333	50	35	be	be	AUX
dti-1333	50	36	important	important	ADJ
dti-1333	50	37	in	in	ADP
dti-1333	50	38	whether	whether	SCONJ
dti-1333	50	39	it	it	PRON
dti-1333	50	40	is	be	AUX
dti-1333	50	41	protective	protective	ADJ
dti-1333	50	42	.	.	PUNCT
dti-1333	51	1	the	the	DET
dti-1333	51	2	familial	familial	ADJ
dti-1333	51	3	hypoalphalipoproteinemias	hypoalphalipoproteinemia	NOUN
dti-1333	51	4	are	be	AUX
dti-1333	51	5	rare	rare	ADJ
dti-1333	51	6	lipoprotein	lipoprotein	ADJ
dti-1333	51	7	disorders	disorder	NOUN
dti-1333	51	8	characterized	characterize	VERB
dti-1333	51	9	by	by	ADP
dti-1333	51	10	low	low	ADJ
dti-1333	51	11	levels	level	NOUN
dti-1333	51	12	of	of	ADP
dti-1333	51	13	plasma	plasma	NOUN
dti-1333	51	14	hdl	hdl	PROPN
dti-1333	51	15	.	.	PUNCT
dti-1333	52	1	however	however	ADV
dti-1333	52	2	,	,	PUNCT
dti-1333	52	3	despite	despite	SCONJ
dti-1333	52	4	markedly	markedly	ADV
dti-1333	52	5	reduced	reduce	VERB
dti-1333	52	6	hdl	hdl	PROPN
dti-1333	52	7	levels	level	NOUN
dti-1333	52	8	,	,	PUNCT
dti-1333	52	9	several	several	ADJ
dti-1333	52	10	of	of	ADP
dti-1333	52	11	these	these	DET
dti-1333	52	12	conditions	condition	NOUN
dti-1333	52	13	,	,	PUNCT
dti-1333	52	14	including	include	VERB
dti-1333	52	15	tangier	tangy	ADJ
dti-1333	52	16	disease	disease	NOUN
dti-1333	52	17	,	,	PUNCT
dti-1333	52	18	fi	fi	NOUN
dti-1333	52	19	sh	sh	PROPN
dti-1333	52	20	eye	eye	NOUN
dti-1333	52	21	disease	disease	NOUN
dti-1333	52	22	,	,	PUNCT
dti-1333	52	23	and	and	CCONJ
dti-1333	52	24	lcat	lcat	ADJ
dti-1333	52	25	defi	defi	NOUN
dti-1333	52	26	ciency	ciency	NOUN
dti-1333	52	27	,	,	PUNCT
dti-1333	52	28	are	be	AUX
dti-1333	52	29	not	not	PART
dti-1333	52	30	associated	associate	VERB
dti-1333	52	31	with	with	ADP
dti-1333	52	32	premature	premature	ADJ
dti-1333	52	33	atherosclerosis	atherosclerosis	NOUN
dti-1333	52	34	.	.	PUNCT
dti-1333	53	1	however	however	ADV
dti-1333	53	2	,	,	PUNCT
dti-1333	53	3	some	some	DET
dti-1333	53	4	mutations	mutation	NOUN
dti-1333	53	5	in	in	ADP
dti-1333	53	6	lcat	lcat	ADJ
dti-1333	53	7	are	be	AUX
dti-1333	53	8	known	know	VERB
dti-1333	53	9	that	that	PRON
dti-1333	53	10	do	do	AUX
dti-1333	53	11	result	result	VERB
dti-1333	53	12	in	in	ADP
dti-1333	53	13	increased	increase	VERB
dti-1333	53	14	cad	cad	PROPN
dti-1333	53	15	(	(	PUNCT
dti-1333	53	16	vega	vega	PROPN
dti-1333	53	17	and	and	CCONJ
dti-1333	53	18	grundy	grundy	PROPN
dti-1333	53	19	,	,	PUNCT
dti-1333	53	20	1996	1996	NUM
dti-1333	53	21	;	;	PUNCT
dti-1333	53	22	frohlich	frohlich	PROPN
dti-1333	53	23	et	et	PROPN
dti-1333	53	24	al	al	PROPN
dti-1333	53	25	.	.	PROPN
dti-1333	53	26	1990	1990	NUM
dti-1333	53	27	)	)	PUNCT
dti-1333	53	28	.	.	PUNCT
dti-1333	54	1	mutations	mutation	NOUN
dti-1333	54	2	leading	lead	VERB
dti-1333	54	3	to	to	ADP
dti-1333	54	4	reduced	reduce	VERB
dti-1333	54	5	cetp	cetp	NOUN
dti-1333	54	6	activity	activity	NOUN
dti-1333	54	7	result	result	NOUN
dti-1333	54	8	in	in	ADP
dti-1333	54	9	less	less	ADJ
dti-1333	54	10	ce	ce	VERB
dti-1333	54	11	being	be	AUX
dti-1333	54	12	directed	direct	VERB
dti-1333	54	13	into	into	ADP
dti-1333	54	14	apo	apo	PROPN
dti-1333	54	15	-	-	PUNCT
dti-1333	54	16	b	b	NOUN
dti-1333	54	17	-	-	PUNCT
dti-1333	54	18	containing	contain	VERB
dti-1333	54	19	particles	particle	NOUN
dti-1333	54	20	(	(	PUNCT
dti-1333	54	21	vldl	vldl	NOUN
dti-1333	54	22	and	and	CCONJ
dti-1333	54	23	ldl	ldl	NOUN
dti-1333	54	24	)	)	PUNCT
dti-1333	54	25	and	and	CCONJ
dti-1333	54	26	more	more	ADJ
dti-1333	54	27	remaining	remain	VERB
dti-1333	54	28	in	in	ADP
dti-1333	54	29	hdl	hdl	PROPN
dti-1333	54	30	,	,	PUNCT
dti-1333	54	31	resulting	result	VERB
dti-1333	54	32	in	in	ADP
dti-1333	54	33	increased	increase	VERB
dti-1333	54	34	hdl	hdl	PROPN
dti-1333	54	35	-	-	PUNCT
dti-1333	54	36	c	c	NOUN
dti-1333	54	37	concentrations	concentration	NOUN
dti-1333	54	38	.	.	PUNCT
dti-1333	55	1	mutations	mutation	NOUN
dti-1333	55	2	leading	lead	VERB
dti-1333	55	3	to	to	ADP
dti-1333	55	4	reduced	reduce	VERB
dti-1333	55	5	hepatic	hepatic	ADJ
dti-1333	55	6	lipase	lipase	NOUN
dti-1333	55	7	(	(	PUNCT
dti-1333	55	8	hl	hl	NOUN
dti-1333	55	9	)	)	PUNCT
dti-1333	55	10	activity	activity	NOUN
dti-1333	55	11	are	be	AUX
dti-1333	55	12	rare	rare	ADJ
dti-1333	55	13	and	and	CCONJ
dti-1333	55	14	are	be	AUX
dti-1333	55	15	associated	associate	VERB
dti-1333	55	16	with	with	ADP
dti-1333	55	17	increased	increase	VERB
dti-1333	55	18	hdl	hdl	PROPN
dti-1333	55	19	-	-	PUNCT
dti-1333	55	20	c	c	NOUN
dti-1333	55	21	concentrations	concentration	NOUN
dti-1333	55	22	and	and	CCONJ
dti-1333	55	23	cad	cad	PROPN
dti-1333	55	24	.	.	PUNCT
dti-1333	55	25	tangier	tangy	ADJ
dti-1333	55	26	disease	disease	NOUN
dti-1333	55	27	(	(	PUNCT
dti-1333	55	28	td	td	NOUN
dti-1333	55	29	)	)	PUNCT
dti-1333	55	30	the	the	DET
dti-1333	55	31	atp	atp	NOUN
dti-1333	55	32	-	-	PUNCT
dti-1333	55	33	binding	bind	VERB
dti-1333	55	34	cassette	cassette	NOUN
dti-1333	55	35	transporter	transporter	NOUN
dti-1333	55	36	a1	a1	NOUN
dti-1333	55	37	(	(	PUNCT
dti-1333	55	38	abca1	abca1	NOUN
dti-1333	55	39	)	)	PUNCT
dti-1333	55	40	protein	protein	NOUN
dti-1333	55	41	regulates	regulate	VERB
dti-1333	55	42	the	the	DET
dti-1333	55	43	effl	effl	PROPN
dti-1333	55	44	ux	ux	PROPN
dti-1333	55	45	of	of	ADP
dti-1333	55	46	cholesterol	cholesterol	NOUN
dti-1333	55	47	and	and	CCONJ
dti-1333	55	48	phospholipids	phospholipid	NOUN
dti-1333	55	49	from	from	ADP
dti-1333	55	50	the	the	DET
dti-1333	55	51	cell	cell	NOUN
dti-1333	55	52	to	to	PART
dti-1333	55	53	apolipoprotein	apolipoprotein	VERB
dti-1333	55	54	acceptors	acceptor	NOUN
dti-1333	55	55	,	,	PUNCT
dti-1333	55	56	47	47	NUM
dti-1333	55	57	therapies	therapy	NOUN
dti-1333	55	58	to	to	PART
dti-1333	55	59	increase	increase	VERB
dti-1333	55	60	apoa-1	apoa-1	NUM
dti-1333	55	61	and	and	CCONJ
dti-1333	55	62	hdl	hdl	PROPN
dti-1333	55	63	-	-	PUNCT
dti-1333	55	64	cholesterol	cholesterol	NOUN
dti-1333	55	65	levels	level	NOUN
dti-1333	55	66	drug	drug	NOUN
dti-1333	55	67	target	target	NOUN
dti-1333	55	68	insights	insight	NOUN
dti-1333	55	69	2008:3	2008:3	NUM
dti-1333	55	70	the	the	DET
dti-1333	55	71	rate	rate	NOUN
dti-1333	55	72	-	-	PUNCT
dti-1333	55	73	limiting	limit	VERB
dti-1333	55	74	step	step	NOUN
dti-1333	55	75	in	in	ADP
dti-1333	55	76	the	the	DET
dti-1333	55	77	removal	removal	NOUN
dti-1333	55	78	of	of	ADP
dti-1333	55	79	cellular	cellular	ADJ
dti-1333	55	80	cholesterol	cholesterol	NOUN
dti-1333	55	81	.	.	PUNCT
dti-1333	56	1	tangier	tangy	ADJ
dti-1333	56	2	disease	disease	NOUN
dti-1333	56	3	is	be	AUX
dti-1333	56	4	characterized	characterize	VERB
dti-1333	56	5	by	by	ADP
dti-1333	56	6	mutations	mutation	NOUN
dti-1333	56	7	in	in	ADP
dti-1333	56	8	the	the	DET
dti-1333	56	9	abca1	abca1	NOUN
dti-1333	56	10	gene	gene	NOUN
dti-1333	56	11	,	,	PUNCT
dti-1333	56	12	resulting	result	VERB
dti-1333	56	13	in	in	ADP
dti-1333	56	14	a	a	DET
dti-1333	56	15	defective	defective	ADJ
dti-1333	56	16	abca1	abca1	NOUN
dti-1333	56	17	protein	protein	NOUN
dti-1333	56	18	and	and	CCONJ
dti-1333	56	19	accumulation	accumulation	NOUN
dti-1333	56	20	of	of	ADP
dti-1333	56	21	cellular	cellular	ADJ
dti-1333	56	22	cholesterol	cholesterol	NOUN
dti-1333	56	23	,	,	PUNCT
dti-1333	56	24	reduced	reduce	VERB
dti-1333	56	25	plasma	plasma	NOUN
dti-1333	56	26	hdl	hdl	PROPN
dti-1333	56	27	-	-	PUNCT
dti-1333	56	28	c	c	PROPN
dti-1333	56	29	,	,	PUNCT
dti-1333	56	30	and	and	CCONJ
dti-1333	56	31	increased	increase	VERB
dti-1333	56	32	risk	risk	NOUN
dti-1333	56	33	for	for	ADP
dti-1333	56	34	cad	cad	NOUN
dti-1333	56	35	;	;	PUNCT
dti-1333	56	36	over	over	ADP
dti-1333	56	37	100	100	NUM
dti-1333	56	38	abca1	abca1	NOUN
dti-1333	56	39	coding	code	VERB
dti-1333	56	40	variants	variant	NOUN
dti-1333	56	41	are	be	AUX
dti-1333	56	42	known	know	VERB
dti-1333	56	43	(	(	PUNCT
dti-1333	56	44	wang	wang	PROPN
dti-1333	56	45	et	et	PROPN
dti-1333	56	46	al	al	PROPN
dti-1333	56	47	.	.	PROPN
dti-1333	56	48	2000	2000	NUM
dti-1333	56	49	;	;	PUNCT
dti-1333	56	50	oram	oram	PROPN
dti-1333	56	51	,	,	PUNCT
dti-1333	56	52	2000	2000	NUM
dti-1333	56	53	,	,	PUNCT
dti-1333	56	54	2001	2001	NUM
dti-1333	56	55	;	;	PUNCT
dti-1333	56	56	brunham	brunham	PROPN
dti-1333	56	57	et	et	PROPN
dti-1333	56	58	al	al	PROPN
dti-1333	56	59	.	.	PROPN
dti-1333	56	60	2006	2006	NUM
dti-1333	56	61	;	;	PUNCT
dti-1333	56	62	kolovou	kolovou	PROPN
dti-1333	56	63	et	et	PROPN
dti-1333	56	64	al	al	PROPN
dti-1333	56	65	.	.	PROPN
dti-1333	56	66	2006	2006	NUM
dti-1333	56	67	;	;	PUNCT
dti-1333	56	68	tall	tall	ADJ
dti-1333	56	69	and	and	CCONJ
dti-1333	56	70	wang	wang	PROPN
dti-1333	56	71	,	,	PUNCT
dti-1333	56	72	2000	2000	NUM
dti-1333	56	73	)	)	PUNCT
dti-1333	56	74	.	.	PUNCT
dti-1333	57	1	the	the	DET
dti-1333	57	2	plasma	plasma	NOUN
dti-1333	57	3	of	of	ADP
dti-1333	57	4	td	td	NOUN
dti-1333	57	5	patients	patient	NOUN
dti-1333	57	6	has	have	VERB
dti-1333	57	7	essentially	essentially	ADV
dti-1333	57	8	no	no	DET
dti-1333	57	9	apoa	apoa	NOUN
dti-1333	57	10	-	-	PUNCT
dti-1333	57	11	i	i	PRON
dti-1333	57	12	-	-	PUNCT
dti-1333	57	13	containing	contain	VERB
dti-1333	57	14	lipoprotein	lipoprotein	NOUN
dti-1333	57	15	(	(	PUNCT
dti-1333	57	16	α	α	NOUN
dti-1333	57	17	-	-	PUNCT
dti-1333	57	18	lpa	lpa	NOUN
dti-1333	57	19	-	-	PUNCT
dti-1333	57	20	i	i	PROPN
dti-1333	57	21	)	)	PUNCT
dti-1333	57	22	,	,	PUNCT
dti-1333	57	23	which	which	PRON
dti-1333	57	24	in	in	ADP
dti-1333	57	25	normolipidemic	normolipidemic	ADJ
dti-1333	57	26	plasma	plasma	NOUN
dti-1333	57	27	is	be	AUX
dti-1333	57	28	the	the	DET
dti-1333	57	29	majority	majority	NOUN
dti-1333	57	30	of	of	ADP
dti-1333	57	31	hdl	hdl	PROPN
dti-1333	57	32	.	.	PUNCT
dti-1333	57	33	residual	residual	ADJ
dti-1333	57	34	amounts	amount	NOUN
dti-1333	57	35	of	of	ADP
dti-1333	57	36	apoa	apoa	NOUN
dti-1333	57	37	-	-	PUNCT
dti-1333	57	38	i	i	PRON
dti-1333	57	39	in	in	ADP
dti-1333	57	40	td	td	NOUN
dti-1333	57	41	plasma	plasma	NOUN
dti-1333	57	42	have	have	VERB
dti-1333	57	43	electrophoretic	electrophoretic	ADJ
dti-1333	57	44	preβ1	preβ1	NOUN
dti-1333	57	45	-	-	PUNCT
dti-1333	57	46	lpa	lpa	NOUN
dti-1333	57	47	-	-	PUNCT
dti-1333	57	48	i	i	NOUN
dti-1333	57	49	mobility	mobility	NOUN
dti-1333	57	50	.	.	PUNCT
dti-1333	58	1	cetp	cetp	PROPN
dti-1333	58	2	defi	defi	PROPN
dti-1333	58	3	ciency	ciency	PROPN
dti-1333	58	4	cetp	cetp	PROPN
dti-1333	58	5	defi	defi	PROPN
dti-1333	58	6	ciency	ciency	NOUN
dti-1333	58	7	causes	cause	VERB
dti-1333	58	8	hyperalphalipoproteinemia	hyperalphalipoproteinemia	NOUN
dti-1333	58	9	,	,	PUNCT
dti-1333	58	10	that	that	ADV
dti-1333	58	11	is	is	ADV
dti-1333	58	12	,	,	PUNCT
dti-1333	58	13	marked	mark	VERB
dti-1333	58	14	elevation	elevation	NOUN
dti-1333	58	15	of	of	ADP
dti-1333	58	16	plasma	plasma	NOUN
dti-1333	58	17	hdl	hdl	PROPN
dti-1333	58	18	-	-	PUNCT
dti-1333	58	19	c	c	PROPN
dti-1333	58	20	(	(	PUNCT
dti-1333	58	21	e.g.	e.g.	ADV
dti-1333	58	22	nagano	nagano	PROPN
dti-1333	58	23	et	et	PROPN
dti-1333	58	24	al	al	PROPN
dti-1333	58	25	.	.	PROPN
dti-1333	58	26	2004	2004	NUM
dti-1333	58	27	;	;	PUNCT
dti-1333	58	28	yamashita	yamashita	PROPN
dti-1333	58	29	et	et	PROPN
dti-1333	58	30	al	al	PROPN
dti-1333	58	31	.	.	PROPN
dti-1333	58	32	2000	2000	NUM
dti-1333	58	33	)	)	PUNCT
dti-1333	58	34	.	.	PUNCT
dti-1333	59	1	while	while	SCONJ
dti-1333	59	2	the	the	DET
dti-1333	59	3	extent	extent	NOUN
dti-1333	59	4	to	to	PART
dti-1333	59	5	which	which	PRON
dti-1333	59	6	cetp	cetp	NOUN
dti-1333	59	7	defi	defi	NOUN
dti-1333	59	8	ciency	ciency	NOUN
dti-1333	59	9	is	be	AUX
dti-1333	59	10	actually	actually	ADV
dti-1333	59	11	associated	associate	VERB
dti-1333	59	12	with	with	ADP
dti-1333	59	13	protection	protection	NOUN
dti-1333	59	14	against	against	ADP
dti-1333	59	15	cad	cad	PROPN
dti-1333	59	16	is	be	AUX
dti-1333	59	17	unclear	unclear	ADJ
dti-1333	59	18	,	,	PUNCT
dti-1333	59	19	it	it	PRON
dti-1333	59	20	gave	give	VERB
dti-1333	59	21	rise	rise	NOUN
dti-1333	59	22	to	to	ADP
dti-1333	59	23	the	the	DET
dti-1333	59	24	idea	idea	NOUN
dti-1333	59	25	of	of	ADP
dti-1333	59	26	inhibiting	inhibit	VERB
dti-1333	59	27	cetp	cetp	NOUN
dti-1333	59	28	as	as	ADP
dti-1333	59	29	a	a	DET
dti-1333	59	30	therapeutic	therapeutic	ADJ
dti-1333	59	31	strategy	strategy	NOUN
dti-1333	59	32	(	(	PUNCT
dti-1333	59	33	shah	shah	NOUN
dti-1333	59	34	,	,	PUNCT
dti-1333	59	35	2007a	2007a	NUM
dti-1333	59	36	;	;	PUNCT
dti-1333	59	37	van	van	PROPN
dti-1333	59	38	der	der	PROPN
dti-1333	59	39	steeg	steeg	PROPN
dti-1333	59	40	et	et	PROPN
dti-1333	59	41	al	al	PROPN
dti-1333	59	42	.	.	PROPN
dti-1333	59	43	2005	2005	NUM
dti-1333	59	44	;	;	PUNCT
dti-1333	59	45	forrester	forrester	PROPN
dti-1333	59	46	et	et	PROPN
dti-1333	59	47	al	al	PROPN
dti-1333	59	48	.	.	PROPN
dti-1333	59	49	2005	2005	NUM
dti-1333	59	50	;	;	PUNCT
dti-1333	59	51	doggrell	doggrell	NOUN
dti-1333	59	52	,	,	PUNCT
dti-1333	59	53	2004	2004	NUM
dti-1333	59	54	;	;	PUNCT
dti-1333	59	55	barter	barter	NOUN
dti-1333	59	56	and	and	CCONJ
dti-1333	59	57	kastelein	kastelein	ADV
dti-1333	59	58	,	,	PUNCT
dti-1333	59	59	2006	2006	NUM
dti-1333	59	60	;	;	PUNCT
dti-1333	59	61	barter	barter	NOUN
dti-1333	59	62	et	et	PROPN
dti-1333	59	63	al	al	PROPN
dti-1333	59	64	.	.	PROPN
dti-1333	59	65	2003	2003	NUM
dti-1333	59	66	)	)	PUNCT
dti-1333	59	67	.	.	PUNCT
dti-1333	60	1	lecithin	lecithin	NOUN
dti-1333	60	2	:	:	PUNCT
dti-1333	60	3	cholesterol	cholesterol	NOUN
dti-1333	60	4	acyltransferase	acyltransferase	PROPN
dti-1333	60	5	(	(	PUNCT
dti-1333	60	6	lcat	lcat	ADJ
dti-1333	60	7	)	)	PUNCT
dti-1333	60	8	defi	defi	NOUN
dti-1333	60	9	ciency	ciency	NOUN
dti-1333	60	10	and	and	CCONJ
dti-1333	60	11	fi	fi	NOUN
dti-1333	61	1	sh	sh	PROPN
dti-1333	61	2	eye	eye	NOUN
dti-1333	61	3	disease	disease	NOUN
dti-1333	61	4	lcat	lcat	ADJ
dti-1333	61	5	esterifi	esterifi	NOUN
dti-1333	61	6	es	es	ADP
dti-1333	61	7	free	free	ADJ
dti-1333	61	8	cholesterol	cholesterol	NOUN
dti-1333	61	9	in	in	ADP
dti-1333	61	10	plasma	plasma	NOUN
dti-1333	61	11	and	and	CCONJ
dti-1333	61	12	is	be	AUX
dti-1333	61	13	important	important	ADJ
dti-1333	61	14	in	in	ADP
dti-1333	61	15	the	the	DET
dti-1333	61	16	maturation	maturation	NOUN
dti-1333	61	17	of	of	ADP
dti-1333	61	18	preβ	preβ	NOUN
dti-1333	61	19	-	-	PUNCT
dti-1333	61	20	hdl	hdl	NOUN
dti-1333	61	21	(	(	PUNCT
dti-1333	61	22	lipid	lipid	NOUN
dti-1333	61	23	-	-	PUNCT
dti-1333	61	24	poor	poor	ADJ
dti-1333	61	25	hdl	hdl	NOUN
dti-1333	61	26	)	)	PUNCT
dti-1333	61	27	into	into	ADP
dti-1333	61	28	α	α	NOUN
dti-1333	61	29	-	-	PUNCT
dti-1333	61	30	migrating	migrating	ADJ
dti-1333	61	31	hdl	hdl	NOUN
dti-1333	61	32	(	(	PUNCT
dti-1333	61	33	spherical	spherical	ADJ
dti-1333	61	34	hdl	hdl	PROPN
dti-1333	61	35	)	)	PUNCT
dti-1333	61	36	.	.	PUNCT
dti-1333	62	1	primary	primary	ADJ
dti-1333	62	2	(	(	PUNCT
dti-1333	62	3	familial	familial	ADJ
dti-1333	62	4	)	)	PUNCT
dti-1333	62	5	lcat	lcat	ADJ
dti-1333	62	6	defi	defi	NOUN
dti-1333	62	7	ciency	ciency	NOUN
dti-1333	62	8	(	(	PUNCT
dti-1333	62	9	fld	fld	NOUN
dti-1333	62	10	)	)	PUNCT
dti-1333	62	11	is	be	AUX
dti-1333	62	12	a	a	DET
dti-1333	62	13	genetic	genetic	ADJ
dti-1333	62	14	disease	disease	NOUN
dti-1333	62	15	associated	associate	VERB
dti-1333	62	16	with	with	ADP
dti-1333	62	17	corneal	corneal	ADJ
dti-1333	62	18	opacity	opacity	NOUN
dti-1333	62	19	,	,	PUNCT
dti-1333	62	20	anemia	anemia	NOUN
dti-1333	62	21	,	,	PUNCT
dti-1333	62	22	and	and	CCONJ
dti-1333	62	23	proteinuria	proteinuria	NOUN
dti-1333	62	24	with	with	ADP
dti-1333	62	25	renal	renal	ADJ
dti-1333	62	26	failure	failure	NOUN
dti-1333	62	27	.	.	PUNCT
dti-1333	63	1	it	it	PRON
dti-1333	63	2	is	be	AUX
dti-1333	63	3	caused	cause	VERB
dti-1333	63	4	by	by	ADP
dti-1333	63	5	the	the	DET
dti-1333	63	6	complete	complete	ADJ
dti-1333	63	7	or	or	CCONJ
dti-1333	63	8	near	near	ADP
dti-1333	63	9	absence	absence	NOUN
dti-1333	63	10	of	of	ADP
dti-1333	63	11	lcat	lcat	ADJ
dti-1333	63	12	activity	activity	NOUN
dti-1333	63	13	.	.	PUNCT
dti-1333	64	1	fish	fish	NOUN
dti-1333	64	2	eye	eye	NOUN
dti-1333	64	3	disease	disease	NOUN
dti-1333	64	4	(	(	PUNCT
dti-1333	64	5	fed	fed	PROPN
dti-1333	64	6	)	)	PUNCT
dti-1333	64	7	is	be	AUX
dti-1333	64	8	a	a	DET
dti-1333	64	9	related	relate	VERB
dti-1333	64	10	,	,	PUNCT
dti-1333	64	11	milder	mild	ADJ
dti-1333	64	12	condition	condition	NOUN
dti-1333	64	13	in	in	ADP
dti-1333	64	14	which	which	PRON
dti-1333	64	15	there	there	PRON
dti-1333	64	16	is	be	VERB
dti-1333	64	17	some	some	DET
dti-1333	64	18	residual	residual	ADJ
dti-1333	64	19	lcat	lcat	ADJ
dti-1333	64	20	activity	activity	NOUN
dti-1333	64	21	.	.	PUNCT
dti-1333	65	1	characteristic	characteristic	ADJ
dti-1333	65	2	features	feature	NOUN
dti-1333	65	3	of	of	ADP
dti-1333	65	4	fed	fed	PROPN
dti-1333	65	5	include	include	VERB
dti-1333	65	6	corneal	corneal	ADJ
dti-1333	65	7	opacities	opacity	NOUN
dti-1333	65	8	,	,	PUNCT
dti-1333	65	9	hdl	hdl	PROPN
dti-1333	65	10	-	-	PUNCT
dti-1333	65	11	c	c	PROPN
dti-1333	65	12	below	below	ADP
dti-1333	65	13	10	10	NUM
dti-1333	65	14	mg	mg	PROPN
dti-1333	65	15	/	/	SYM
dti-1333	65	16	dl	dl	PROPN
dti-1333	65	17	,	,	PUNCT
dti-1333	65	18	normal	normal	ADJ
dti-1333	65	19	plasma	plasma	NOUN
dti-1333	65	20	cholesteryl	cholesteryl	PROPN
dti-1333	65	21	esters	ester	NOUN
dti-1333	65	22	,	,	PUNCT
dti-1333	65	23	and	and	CCONJ
dti-1333	65	24	elevated	elevate	VERB
dti-1333	65	25	triglyceride	triglyceride	ADJ
dti-1333	65	26	levels	level	NOUN
dti-1333	65	27	.	.	PUNCT
dti-1333	66	1	in	in	ADP
dti-1333	66	2	fed	fed	PROPN
dti-1333	66	3	,	,	PUNCT
dti-1333	66	4	hypoalphalipoproteinemia	hypoalphalipoproteinemia	NOUN
dti-1333	66	5	is	be	AUX
dti-1333	66	6	caused	cause	VERB
dti-1333	66	7	by	by	ADP
dti-1333	66	8	marked	mark	VERB
dti-1333	66	9	hypercatabolism	hypercatabolism	NOUN
dti-1333	66	10	of	of	ADP
dti-1333	66	11	apoa	apoa	NOUN
dti-1333	66	12	-	-	PUNCT
dti-1333	66	13	i	i	PROPN
dti-1333	66	14	and	and	CCONJ
dti-1333	66	15	apoa	apoa	PROPN
dti-1333	66	16	-	-	PUNCT
dti-1333	66	17	il	il	PROPN
dti-1333	66	18	.	.	PROPN
dti-1333	66	19	apoa	apoa	PROPN
dti-1333	66	20	-	-	PUNCT
dti-1333	66	21	imilano	imilano	PROPN
dti-1333	66	22	and	and	CCONJ
dti-1333	66	23	apoa	apoa	NOUN
dti-1333	66	24	-	-	PUNCT
dti-1333	66	25	iparis	iparis	NOUN
dti-1333	66	26	apoa	apoa	NOUN
dti-1333	66	27	-	-	PUNCT
dti-1333	66	28	imilano	imilano	PROPN
dti-1333	66	29	and	and	CCONJ
dti-1333	66	30	apoa	apoa	NOUN
dti-1333	66	31	-	-	PUNCT
dti-1333	66	32	iparis	iparis	NOUN
dti-1333	66	33	are	be	AUX
dti-1333	66	34	naturally	naturally	ADV
dti-1333	66	35	occurring	occur	VERB
dti-1333	66	36	variants	variant	NOUN
dti-1333	66	37	of	of	ADP
dti-1333	66	38	apoa	apoa	PROPN
dti-1333	66	39	-	-	PUNCT
dti-1333	66	40	i	i	PRON
dti-1333	66	41	associated	associate	VERB
dti-1333	66	42	with	with	ADP
dti-1333	66	43	low	low	ADJ
dti-1333	66	44	rates	rate	NOUN
dti-1333	66	45	of	of	ADP
dti-1333	66	46	vascular	vascular	ADJ
dti-1333	66	47	disease	disease	NOUN
dti-1333	66	48	and	and	CCONJ
dti-1333	66	49	longevity	longevity	NOUN
dti-1333	66	50	in	in	ADP
dti-1333	66	51	their	their	PRON
dti-1333	66	52	carriers	carrier	NOUN
dti-1333	66	53	.	.	PUNCT
dti-1333	67	1	carriers	carrier	NOUN
dti-1333	67	2	of	of	ADP
dti-1333	67	3	apoa	apoa	NOUN
dti-1333	67	4	-	-	PUNCT
dti-1333	67	5	imilano	imilano	PROPN
dti-1333	67	6	have	have	AUX
dti-1333	67	7	reduced	reduce	VERB
dti-1333	67	8	levels	level	NOUN
dti-1333	67	9	of	of	ADP
dti-1333	67	10	ldl	ldl	NOUN
dti-1333	67	11	-	-	PUNCT
dti-1333	67	12	c	c	PROPN
dti-1333	67	13	and	and	CCONJ
dti-1333	67	14	very	very	ADV
dti-1333	67	15	low	low	ADJ
dti-1333	67	16	levels	level	NOUN
dti-1333	67	17	of	of	ADP
dti-1333	67	18	hdl	hdl	PROPN
dti-1333	67	19	.	.	PROPN
dti-1333	67	20	apoa	apoa	PROPN
dti-1333	67	21	-	-	PUNCT
dti-1333	67	22	imilano	imilano	PROPN
dti-1333	67	23	is	be	AUX
dti-1333	67	24	characterized	characterize	VERB
dti-1333	67	25	by	by	ADP
dti-1333	67	26	a	a	DET
dti-1333	67	27	cysteine	cysteine	NOUN
dti-1333	67	28	-	-	PUNCT
dti-1333	67	29	for	for	ADP
dti-1333	67	30	-	-	PUNCT
dti-1333	67	31	arginine	arginine	NOUN
dti-1333	67	32	substitution	substitution	NOUN
dti-1333	67	33	at	at	ADP
dti-1333	67	34	low	low	ADJ
dti-1333	67	35	-	-	PUNCT
dti-1333	67	36	density	density	NOUN
dti-1333	67	37	lipoprotein	lipoprotein	ADJ
dti-1333	67	38	high	high	ADJ
dti-1333	67	39	-	-	PUNCT
dti-1333	67	40	density	density	NOUN
dti-1333	67	41	lipoprotein	lipoprotein	ADJ
dti-1333	67	42	artery	artery	NOUN
dti-1333	67	43	ldl	ldl	NOUN
dti-1333	67	44	deposits	deposit	VERB
dti-1333	67	45	cholesterol	cholesterol	NOUN
dti-1333	67	46	hdl	hdl	PROPN
dti-1333	67	47	removes	remove	VERB
dti-1333	67	48	cholesterol	cholesterol	NOUN
dti-1333	67	49	cholesterol	cholesterol	NOUN
dti-1333	67	50	deposit	deposit	NOUN
dti-1333	67	51	ldl	ldl	NOUN
dti-1333	67	52	depositing	deposit	VERB
dti-1333	67	53	cholesterol	cholesterol	NOUN
dti-1333	67	54	in	in	ADP
dti-1333	67	55	arteries	artery	NOUN
dti-1333	67	56	increasing	increase	VERB
dti-1333	67	57	risk	risk	NOUN
dti-1333	67	58	of	of	ADP
dti-1333	67	59	atherosclerosis	atherosclerosis	NOUN
dti-1333	67	60	hdl	hdl	NOUN
dti-1333	67	61	removes	remove	VERB
dti-1333	67	62	cholesterol	cholesterol	NOUN
dti-1333	67	63	from	from	ADP
dti-1333	67	64	arteries	artery	NOUN
dti-1333	67	65	atherosclerosis	atherosclerosis	NOUN
dti-1333	67	66	protection	protection	NOUN
dti-1333	67	67	and	and	CCONJ
dti-1333	67	68	regression	regression	NOUN
dti-1333	67	69	liver	liver	NOUN
dti-1333	67	70	discoidal	discoidal	ADJ
dti-1333	67	71	hdl	hdl	PROPN
dti-1333	67	72	mature	mature	PROPN
dti-1333	67	73	hdl	hdl	PROPN
dti-1333	67	74	apoaapoa	apoaapoa	PROPN
dti-1333	67	75	--	--	PUNCT
dti-1333	67	76	ii	ii	NOUN
dti-1333	67	77	cholesterol	cholesterol	NOUN
dti-1333	67	78	elimination	elimination	NOUN
dti-1333	67	79	and	and	CCONJ
dti-1333	67	80	clearance	clearance	NOUN
dti-1333	67	81	figure	figure	NOUN
dti-1333	67	82	1	1	NUM
dti-1333	67	83	.	.	NUM
dti-1333	67	84	48	48	NUM
dti-1333	67	85	brown	brown	ADJ
dti-1333	67	86	and	and	CCONJ
dti-1333	67	87	chiacchia	chiacchia	PROPN
dti-1333	67	88	drug	drug	NOUN
dti-1333	67	89	target	target	NOUN
dti-1333	67	90	insights	insight	NOUN
dti-1333	67	91	2008:3	2008:3	NUM
dti-1333	67	92	position	position	NOUN
dti-1333	67	93	173	173	NUM
dti-1333	67	94	(	(	PUNCT
dti-1333	67	95	r173c	r173c	NOUN
dti-1333	67	96	)	)	PUNCT
dti-1333	67	97	of	of	ADP
dti-1333	67	98	the	the	DET
dti-1333	67	99	protein	protein	NOUN
dti-1333	67	100	sequence	sequence	NOUN
dti-1333	67	101	(	(	PUNCT
dti-1333	67	102	perez	perez	PROPN
dti-1333	67	103	-	-	PUNCT
dti-1333	67	104	mendez	mendez	PROPN
dti-1333	67	105	et	et	PROPN
dti-1333	67	106	al	al	PROPN
dti-1333	67	107	.	.	PROPN
dti-1333	67	108	2000	2000	NUM
dti-1333	67	109	;	;	PUNCT
dti-1333	67	110	klon	klon	PROPN
dti-1333	67	111	et	et	PROPN
dti-1333	67	112	al	al	PROPN
dti-1333	67	113	.	.	PROPN
dti-1333	67	114	2000	2000	NUM
dti-1333	67	115	)	)	PUNCT
dti-1333	67	116	.	.	PUNCT
dti-1333	68	1	despite	despite	SCONJ
dti-1333	68	2	this	this	DET
dti-1333	68	3	apparently	apparently	ADV
dti-1333	68	4	pro	pro	ADJ
dti-1333	68	5	-	-	ADJ
dti-1333	68	6	atherogenic	atherogenic	ADJ
dti-1333	68	7	profi	profi	NOUN
dti-1333	68	8	le	le	X
dti-1333	68	9	,	,	PUNCT
dti-1333	68	10	apoa	apoa	NOUN
dti-1333	68	11	-	-	PUNCT
dti-1333	68	12	imilano	imilano	NOUN
dti-1333	68	13	carriers	carrier	NOUN
dti-1333	68	14	appear	appear	VERB
dti-1333	68	15	to	to	PART
dti-1333	68	16	be	be	AUX
dti-1333	68	17	at	at	ADP
dti-1333	68	18	reduced	reduce	VERB
dti-1333	68	19	risk	risk	NOUN
dti-1333	68	20	for	for	ADP
dti-1333	68	21	cardiovascular	cardiovascular	ADJ
dti-1333	68	22	disease	disease	NOUN
dti-1333	68	23	.	.	PUNCT
dti-1333	69	1	in	in	ADP
dti-1333	69	2	a	a	DET
dti-1333	69	3	pilot	pilot	NOUN
dti-1333	69	4	clinical	clinical	ADJ
dti-1333	69	5	study	study	NOUN
dti-1333	69	6	,	,	PUNCT
dti-1333	69	7	a	a	DET
dti-1333	69	8	complex	complex	NOUN
dti-1333	69	9	of	of	ADP
dti-1333	69	10	recombinant	recombinant	ADJ
dti-1333	69	11	apoa	apoa	NOUN
dti-1333	69	12	-	-	PUNCT
dti-1333	69	13	im	im	NOUN
dti-1333	70	1	i	i	PRON
dti-1333	70	2	l	l	PROPN
dti-1333	70	3	a	a	NOUN
dti-1333	70	4	n	n	NOUN
dti-1333	70	5	o	o	NOUN
dti-1333	70	6	and	and	CCONJ
dti-1333	70	7	1	1	NUM
dti-1333	70	8	-	-	PUNCT
dti-1333	70	9	palmitoyl-2	palmitoyl-2	VERB
dti-1333	70	10	-	-	PUNCT
dti-1333	70	11	oleoyl	oleoyl	ADJ
dti-1333	70	12	phosphatidylcholine	phosphatidylcholine	NOUN
dti-1333	70	13	(	(	PUNCT
dti-1333	70	14	etc-216	etc-216	VERB
dti-1333	70	15	)	)	PUNCT
dti-1333	70	16	showed	show	VERB
dti-1333	70	17	a	a	DET
dti-1333	70	18	signifi	signifi	NOUN
dti-1333	70	19	ca	can	AUX
dti-1333	70	20	nt	not	PART
dti-1333	70	21	reduction	reduction	VERB
dti-1333	70	22	in	in	ADP
dti-1333	70	23	coronary	coronary	ADJ
dti-1333	70	24	plaque	plaque	NOUN
dti-1333	70	25	burden	burden	NOUN
dti-1333	70	26	after	after	ADP
dti-1333	70	27	5	5	NUM
dti-1333	70	28	weekly	weekly	ADJ
dti-1333	70	29	treatments	treatment	NOUN
dti-1333	70	30	,	,	PUNCT
dti-1333	70	31	as	as	SCONJ
dti-1333	70	32	assessed	assess	VERB
dti-1333	70	33	by	by	ADP
dti-1333	70	34	intravascular	intravascular	ADJ
dti-1333	70	35	ultrasound	ultrasound	NOUN
dti-1333	70	36	in	in	ADP
dti-1333	70	37	patients	patient	NOUN
dti-1333	70	38	with	with	ADP
dti-1333	70	39	acute	acute	ADJ
dti-1333	70	40	coronary	coronary	ADJ
dti-1333	70	41	syndrome	syndrome	NOUN
dti-1333	70	42	(	(	PUNCT
dti-1333	70	43	nissen	nissen	PROPN
dti-1333	70	44	et	et	PROPN
dti-1333	70	45	al	al	PROPN
dti-1333	70	46	.	.	PROPN
dti-1333	70	47	2003	2003	NUM
dti-1333	70	48	)	)	PUNCT
dti-1333	70	49	.	.	PUNCT
dti-1333	71	1	apoa	apoa	NOUN
dti-1333	71	2	-	-	PUNCT
dti-1333	71	3	iparis	iparis	PROPN
dti-1333	71	4	is	be	AUX
dti-1333	71	5	similarly	similarly	ADV
dti-1333	71	6	characterized	characterize	VERB
dti-1333	71	7	by	by	ADP
dti-1333	71	8	a	a	DET
dti-1333	71	9	cysteinefor	cysteinefor	ADJ
dti-1333	71	10	-	-	PUNCT
dti-1333	71	11	arginine	arginine	NOUN
dti-1333	71	12	substitution	substitution	NOUN
dti-1333	71	13	,	,	PUNCT
dti-1333	71	14	at	at	ADP
dti-1333	71	15	position	position	NOUN
dti-1333	71	16	151	151	NUM
dti-1333	71	17	(	(	PUNCT
dti-1333	71	18	r151c	r151c	PROPN
dti-1333	71	19	)	)	PUNCT
dti-1333	71	20	.	.	PUNCT
dti-1333	72	1	these	these	DET
dti-1333	72	2	cysteine	cysteine	NOUN
dti-1333	72	3	-	-	PUNCT
dti-1333	72	4	for	for	ADP
dti-1333	72	5	-	-	PUNCT
dti-1333	72	6	arginine	arginine	NOUN
dti-1333	72	7	substitutions	substitution	NOUN
dti-1333	72	8	allow	allow	VERB
dti-1333	72	9	disulfi	disulfi	PROPN
dti-1333	72	10	de	de	ADJ
dti-1333	72	11	-	-	ADJ
dti-1333	72	12	linked	link	VERB
dti-1333	72	13	dimers	dimer	NOUN
dti-1333	72	14	to	to	PART
dti-1333	72	15	form	form	VERB
dti-1333	72	16	.	.	PUNCT
dti-1333	73	1	the	the	DET
dti-1333	73	2	mutations	mutation	NOUN
dti-1333	73	3	appear	appear	VERB
dti-1333	73	4	to	to	PART
dti-1333	73	5	make	make	VERB
dti-1333	73	6	the	the	DET
dti-1333	73	7	apoa	apoa	NOUN
dti-1333	73	8	-	-	PUNCT
dti-1333	73	9	imilano	imilano	PROPN
dti-1333	73	10	and	and	CCONJ
dti-1333	73	11	apoa	apoa	NOUN
dti-1333	73	12	-	-	PUNCT
dti-1333	73	13	iparis	iparis	NOUN
dti-1333	73	14	proteins	protein	NOUN
dti-1333	73	15	functionally	functionally	ADV
dti-1333	73	16	more	more	ADV
dti-1333	73	17	effective	effective	ADJ
dti-1333	73	18	than	than	ADP
dti-1333	73	19	normal	normal	ADJ
dti-1333	73	20	apoa	apoa	NOUN
dti-1333	73	21	-	-	PUNCT
dti-1333	73	22	i.	i.	NOUN
dti-1333	73	23	in	in	ADP
dti-1333	73	24	a	a	DET
dti-1333	73	25	rabbit	rabbit	NOUN
dti-1333	73	26	model	model	NOUN
dti-1333	73	27	,	,	PUNCT
dti-1333	73	28	hdl	hdl	PROPN
dti-1333	73	29	formulations	formulation	NOUN
dti-1333	73	30	of	of	ADP
dti-1333	73	31	recombinant	recombinant	ADJ
dti-1333	73	32	apoa	apoa	NOUN
dti-1333	73	33	-	-	PUNCT
dti-1333	73	34	imilano	imilano	NOUN
dti-1333	73	35	-	-	PUNCT
dti-1333	73	36	phospholipid	phospholipid	NOUN
dti-1333	73	37	complexes	complex	NOUN
dti-1333	73	38	brought	bring	VERB
dti-1333	73	39	about	about	ADP
dti-1333	73	40	rapid	rapid	ADJ
dti-1333	73	41	regression	regression	NOUN
dti-1333	73	42	of	of	ADP
dti-1333	73	43	a	a	DET
dti-1333	73	44	focal	focal	ADJ
dti-1333	73	45	carotid	carotid	NOUN
dti-1333	73	46	atheroma	atheroma	NOUN
dti-1333	73	47	and	and	CCONJ
dti-1333	73	48	protection	protection	NOUN
dti-1333	73	49	from	from	ADP
dti-1333	73	50	myocardial	myocardial	ADJ
dti-1333	73	51	infarction	infarction	NOUN
dti-1333	73	52	(	(	PUNCT
dti-1333	73	53	nicholls	nicholl	NOUN
dti-1333	73	54	et	et	PROPN
dti-1333	73	55	al	al	PROPN
dti-1333	73	56	.	.	PROPN
dti-1333	73	57	2005	2005	NUM
dti-1333	73	58	)	)	PUNCT
dti-1333	73	59	.	.	PUNCT
dti-1333	74	1	hdl	hdl	PROPN
dti-1333	74	2	infusion	infusion	PROPN
dti-1333	74	3	several	several	ADJ
dti-1333	74	4	infusion	infusion	NOUN
dti-1333	74	5	studies	study	NOUN
dti-1333	74	6	with	with	ADP
dti-1333	74	7	nascent	nascent	ADJ
dti-1333	74	8	hdl	hdl	NOUN
dti-1333	74	9	particles	particle	NOUN
dti-1333	74	10	(	(	PUNCT
dti-1333	74	11	apoa	apoa	NOUN
dti-1333	74	12	-	-	PUNCT
dti-1333	74	13	i	i	PROPN
dti-1333	74	14	/	/	SYM
dti-1333	74	15	phospholipid	phospholipid	NOUN
dti-1333	74	16	complexes	complex	NOUN
dti-1333	74	17	)	)	PUNCT
dti-1333	74	18	have	have	AUX
dti-1333	74	19	demonstrated	demonstrate	VERB
dti-1333	74	20	the	the	DET
dti-1333	74	21	prevention	prevention	NOUN
dti-1333	74	22	and	and	CCONJ
dti-1333	74	23	regression	regression	NOUN
dti-1333	74	24	of	of	ADP
dti-1333	74	25	atherosclerosis	atherosclerosis	NOUN
dti-1333	74	26	(	(	PUNCT
dti-1333	74	27	shah	shah	NOUN
dti-1333	74	28	,	,	PUNCT
dti-1333	74	29	2007b	2007b	NUM
dti-1333	74	30	)	)	PUNCT
dti-1333	74	31	.	.	PUNCT
dti-1333	75	1	in	in	ADP
dti-1333	75	2	cholesterol	cholesterol	NOUN
dti-1333	75	3	-	-	PUNCT
dti-1333	75	4	fed	feed	VERB
dti-1333	75	5	rabbits	rabbit	NOUN
dti-1333	75	6	,	,	PUNCT
dti-1333	75	7	the	the	DET
dti-1333	75	8	effects	effect	NOUN
dti-1333	75	9	of	of	ADP
dti-1333	75	10	short	short	ADJ
dti-1333	75	11	-	-	PUNCT
dti-1333	75	12	term	term	NOUN
dti-1333	75	13	administration	administration	NOUN
dti-1333	75	14	of	of	ADP
dti-1333	75	15	hdl	hdl	PROPN
dti-1333	75	16	and	and	CCONJ
dti-1333	75	17	a	a	DET
dti-1333	75	18	statin	statin	NOUN
dti-1333	75	19	on	on	ADP
dti-1333	75	20	atherosclerosis	atherosclerosis	NOUN
dti-1333	75	21	were	be	AUX
dti-1333	75	22	compared	compare	VERB
dti-1333	75	23	.	.	PUNCT
dti-1333	76	1	aortic	aortic	ADJ
dti-1333	76	2	atherosclerosis	atherosclerosis	NOUN
dti-1333	76	3	was	be	AUX
dti-1333	76	4	established	establish	VERB
dti-1333	76	5	over	over	ADP
dti-1333	76	6	17	17	NUM
dti-1333	76	7	weeks	week	NOUN
dti-1333	76	8	in	in	ADP
dti-1333	76	9	rabbits	rabbit	NOUN
dti-1333	76	10	by	by	ADP
dti-1333	76	11	balloon	balloon	NOUN
dti-1333	76	12	denudation	denudation	NOUN
dti-1333	76	13	and	and	CCONJ
dti-1333	76	14	cholesterol	cholesterol	NOUN
dti-1333	76	15	feeding	feeding	NOUN
dti-1333	76	16	.	.	PUNCT
dti-1333	77	1	animals	animal	NOUN
dti-1333	77	2	then	then	ADV
dti-1333	77	3	received	receive	VERB
dti-1333	77	4	oral	oral	ADJ
dti-1333	77	5	atorvastatin	atorvastatin	NOUN
dti-1333	77	6	(	(	PUNCT
dti-1333	77	7	5	5	NUM
dti-1333	77	8	mg	mg	PROPN
dti-1333	77	9	/	/	SYM
dti-1333	77	10	kg	kg	PROPN
dti-1333	77	11	for	for	ADP
dti-1333	77	12	5	5	NUM
dti-1333	77	13	days	day	NOUN
dti-1333	77	14	)	)	PUNCT
dti-1333	77	15	or	or	CCONJ
dti-1333	77	16	two	two	NUM
dti-1333	77	17	infusions	infusion	NOUN
dti-1333	77	18	of	of	ADP
dti-1333	77	19	hdl	hdl	PROPN
dti-1333	77	20	particles	particle	NOUN
dti-1333	77	21	(	(	PUNCT
dti-1333	77	22	8	8	NUM
dti-1333	77	23	mg	mg	NUM
dti-1333	77	24	/	/	SYM
dti-1333	77	25	kg	kg	PROPN
dti-1333	77	26	apoa	apoa	PROPN
dti-1333	77	27	-	-	PUNCT
dti-1333	77	28	i	i	PROPN
dti-1333	77	29	)	)	PUNCT
dti-1333	77	30	2	2	NUM
dti-1333	77	31	days	day	NOUN
dti-1333	77	32	apart	apart	ADV
dti-1333	77	33	.	.	PUNCT
dti-1333	78	1	lesion	lesion	NOUN
dti-1333	78	2	size	size	NOUN
dti-1333	78	3	and	and	CCONJ
dti-1333	78	4	composition	composition	NOUN
dti-1333	78	5	were	be	AUX
dti-1333	78	6	then	then	ADV
dti-1333	78	7	assessed	assess	VERB
dti-1333	78	8	.	.	PUNCT
dti-1333	79	1	hdl	hdl	PROPN
dti-1333	79	2	,	,	PUNCT
dti-1333	79	3	but	but	CCONJ
dti-1333	79	4	not	not	PART
dti-1333	79	5	atorvastatin	atorvastatin	NOUN
dti-1333	79	6	,	,	PUNCT
dti-1333	79	7	reduced	reduce	VERB
dti-1333	79	8	lesion	lesion	NOUN
dti-1333	79	9	size	size	NOUN
dti-1333	79	10	by	by	ADP
dti-1333	79	11	36	36	NUM
dti-1333	79	12	%	%	NOUN
dti-1333	79	13	(	(	PUNCT
dti-1333	79	14	nicholls	nicholl	NOUN
dti-1333	79	15	et	et	PROPN
dti-1333	79	16	al	al	PROPN
dti-1333	79	17	.	.	PROPN
dti-1333	79	18	2005	2005	NUM
dti-1333	79	19	)	)	PUNCT
dti-1333	79	20	.	.	PUNCT
dti-1333	80	1	in	in	ADP
dti-1333	80	2	patients	patient	NOUN
dti-1333	80	3	with	with	ADP
dti-1333	80	4	heterozygous	heterozygous	ADJ
dti-1333	80	5	familial	familial	ADJ
dti-1333	80	6	hypercholesterolemia	hypercholesterolemia	NOUN
dti-1333	80	7	,	,	PUNCT
dti-1333	80	8	a	a	DET
dti-1333	80	9	single	single	ADJ
dti-1333	80	10	infusion	infusion	NOUN
dti-1333	80	11	with	with	ADP
dti-1333	80	12	recombinant	recombinant	ADJ
dti-1333	80	13	proapoa	proapoa	NOUN
dti-1333	80	14	-	-	PUNCT
dti-1333	80	15	i	i	PRON
dti-1333	80	16	particles	particle	NOUN
dti-1333	80	17	(	(	PUNCT
dti-1333	80	18	precursor	precursor	NOUN
dti-1333	80	19	of	of	ADP
dti-1333	80	20	apoa	apoa	PROPN
dti-1333	80	21	-	-	PUNCT
dti-1333	80	22	i	i	PROPN
dti-1333	80	23	)	)	PUNCT
dti-1333	80	24	resulted	result	VERB
dti-1333	80	25	in	in	ADP
dti-1333	80	26	a	a	DET
dti-1333	80	27	34	34	NUM
dti-1333	80	28	%	%	NOUN
dti-1333	80	29	sustained	sustain	VERB
dti-1333	80	30	10	10	NUM
dti-1333	80	31	-	-	PUNCT
dti-1333	80	32	day	day	NOUN
dti-1333	80	33	increase	increase	NOUN
dti-1333	80	34	in	in	ADP
dti-1333	80	35	cholesterol	cholesterol	NOUN
dti-1333	80	36	excretion	excretion	NOUN
dti-1333	80	37	,	,	PUNCT
dti-1333	80	38	with	with	ADP
dti-1333	80	39	a	a	DET
dti-1333	80	40	net	net	ADJ
dti-1333	80	41	removal	removal	NOUN
dti-1333	80	42	of	of	ADP
dti-1333	80	43	5%–7	5%–7	NUM
dti-1333	80	44	%	%	NOUN
dti-1333	80	45	of	of	ADP
dti-1333	80	46	total	total	ADJ
dti-1333	80	47	body	body	NOUN
dti-1333	80	48	cholesterol	cholesterol	NOUN
dti-1333	80	49	.	.	PUNCT
dti-1333	81	1	fecal	fecal	ADJ
dti-1333	81	2	sterol	sterol	NOUN
dti-1333	81	3	excretion	excretion	NOUN
dti-1333	81	4	was	be	AUX
dti-1333	81	5	measured	measure	VERB
dti-1333	81	6	for	for	ADP
dti-1333	81	7	9	9	NUM
dti-1333	81	8	days	day	NOUN
dti-1333	81	9	before	before	ADV
dti-1333	81	10	and	and	CCONJ
dti-1333	81	11	9	9	NUM
dti-1333	81	12	days	day	NOUN
dti-1333	81	13	after	after	ADP
dti-1333	81	14	an	an	DET
dti-1333	81	15	intravenous	intravenous	ADJ
dti-1333	81	16	infusion	infusion	NOUN
dti-1333	81	17	of	of	ADP
dti-1333	81	18	the	the	DET
dti-1333	81	19	proapoa	proapoa	NOUN
dti-1333	81	20	-	-	PUNCT
dti-1333	81	21	i	i	PRON
dti-1333	81	22	liposome	liposome	VERB
dti-1333	81	23	complexes	complex	NOUN
dti-1333	81	24	.	.	PUNCT
dti-1333	82	1	plasma	plasma	NOUN
dti-1333	82	2	apoa	apoa	PROPN
dti-1333	82	3	-	-	PUNCT
dti-1333	82	4	i	i	PROPN
dti-1333	82	5	and	and	CCONJ
dti-1333	82	6	hdl	hdl	PROPN
dti-1333	82	7	-	-	PUNCT
dti-1333	82	8	c	c	PROPN
dti-1333	82	9	levels	level	NOUN
dti-1333	82	10	increased	increase	VERB
dti-1333	82	11	transiently	transiently	ADV
dti-1333	82	12	during	during	ADP
dti-1333	82	13	the	the	DET
dti-1333	82	14	fi	fi	NOUN
dti-1333	82	15	rst	rst	PROPN
dti-1333	82	16	24	24	NUM
dti-1333	82	17	h.	h.	PROPN
dti-1333	82	18	fecal	fecal	ADJ
dti-1333	82	19	excretion	excretion	NOUN
dti-1333	82	20	of	of	ADP
dti-1333	82	21	cholesterol	cholesterol	NOUN
dti-1333	82	22	(	(	PUNCT
dti-1333	82	23	neutral	neutral	ADJ
dti-1333	82	24	sterols	sterol	NOUN
dti-1333	82	25	and	and	CCONJ
dti-1333	82	26	bile	bile	NOUN
dti-1333	82	27	acids	acid	NOUN
dti-1333	82	28	)	)	PUNCT
dti-1333	82	29	increased	increase	VERB
dti-1333	82	30	in	in	ADP
dti-1333	82	31	all	all	DET
dti-1333	82	32	subjects	subject	NOUN
dti-1333	82	33	.	.	PUNCT
dti-1333	83	1	control	control	NOUN
dti-1333	83	2	infusions	infusion	NOUN
dti-1333	83	3	with	with	ADP
dti-1333	83	4	only	only	ADJ
dti-1333	83	5	liposomes	liposome	NOUN
dti-1333	83	6	in	in	ADP
dti-1333	83	7	two	two	NUM
dti-1333	83	8	of	of	ADP
dti-1333	83	9	the	the	DET
dti-1333	83	10	patients	patient	NOUN
dti-1333	83	11	did	do	AUX
dti-1333	83	12	not	not	PART
dti-1333	83	13	affect	affect	VERB
dti-1333	83	14	cholesterol	cholesterol	NOUN
dti-1333	83	15	excretion	excretion	NOUN
dti-1333	83	16	(	(	PUNCT
dti-1333	83	17	eriksson	eriksson	PROPN
dti-1333	83	18	et	et	PROPN
dti-1333	83	19	al	al	PROPN
dti-1333	83	20	.	.	PROPN
dti-1333	83	21	1999	1999	NUM
dti-1333	83	22	)	)	PUNCT
dti-1333	83	23	.	.	PUNCT
dti-1333	84	1	in	in	ADP
dti-1333	84	2	patients	patient	NOUN
dti-1333	84	3	with	with	ADP
dti-1333	84	4	acute	acute	ADJ
dti-1333	84	5	coronary	coronary	ADJ
dti-1333	84	6	syndrome	syndrome	NOUN
dti-1333	84	7	,	,	PUNCT
dti-1333	84	8	fi	fi	NOUN
dti-1333	84	9	ve	ve	NOUN
dti-1333	84	10	weekly	weekly	ADJ
dti-1333	84	11	infusions	infusion	NOUN
dti-1333	84	12	of	of	ADP
dti-1333	84	13	apoa	apoa	NOUN
dti-1333	84	14	-	-	PUNCT
dti-1333	84	15	imilano	imilano	PROPN
dti-1333	84	16	resulted	result	VERB
dti-1333	84	17	in	in	ADP
dti-1333	84	18	signifi	signifi	NOUN
dti-1333	84	19	ca	can	AUX
dti-1333	84	20	nt	not	PART
dti-1333	84	21	regression	regression	VERB
dti-1333	84	22	of	of	ADP
dti-1333	84	23	coronary	coronary	ADJ
dti-1333	84	24	atherosclerosis	atherosclerosis	NOUN
dti-1333	84	25	(	(	PUNCT
dti-1333	84	26	nissen	nissen	PROPN
dti-1333	84	27	et	et	PROPN
dti-1333	84	28	al	al	PROPN
dti-1333	84	29	.	.	PROPN
dti-1333	84	30	2003	2003	NUM
dti-1333	84	31	)	)	PUNCT
dti-1333	84	32	.	.	PUNCT
dti-1333	85	1	this	this	DET
dti-1333	85	2	study	study	NOUN
dti-1333	85	3	evaluated	evaluate	VERB
dti-1333	85	4	the	the	DET
dti-1333	85	5	effect	effect	NOUN
dti-1333	85	6	of	of	ADP
dti-1333	85	7	intravenous	intravenous	ADJ
dti-1333	85	8	recombinant	recombinant	ADJ
dti-1333	85	9	apoa	apoa	NOUN
dti-1333	85	10	-	-	PUNCT
dti-1333	85	11	imilano	imilano	NOUN
dti-1333	85	12	-	-	PUNCT
dti-1333	85	13	phospholipid	phospholipid	NOUN
dti-1333	85	14	complexes	complex	NOUN
dti-1333	85	15	(	(	PUNCT
dti-1333	85	16	etc-216	etc-216	VERB
dti-1333	85	17	)	)	PUNCT
dti-1333	85	18	on	on	ADP
dti-1333	85	19	atheroma	atheroma	NOUN
dti-1333	85	20	burden	burden	NOUN
dti-1333	85	21	in	in	ADP
dti-1333	85	22	patients	patient	NOUN
dti-1333	85	23	with	with	ADP
dti-1333	85	24	acute	acute	ADJ
dti-1333	85	25	coronary	coronary	ADJ
dti-1333	85	26	syndromes	syndrome	NOUN
dti-1333	85	27	(	(	PUNCT
dti-1333	85	28	n	n	NOUN
dti-1333	85	29	=	=	SYM
dti-1333	85	30	47	47	NUM
dti-1333	85	31	)	)	PUNCT
dti-1333	85	32	.	.	PUNCT
dti-1333	86	1	the	the	DET
dti-1333	86	2	recombinant	recombinant	ADJ
dti-1333	86	3	apoa	apoa	NOUN
dti-1333	86	4	-	-	PUNCT
dti-1333	86	5	imilano	imilano	NOUN
dti-1333	86	6	-	-	PUNCT
dti-1333	86	7	phospholipid	phospholipid	NOUN
dti-1333	86	8	complex	complex	NOUN
dti-1333	86	9	was	be	AUX
dti-1333	86	10	administered	administer	VERB
dti-1333	86	11	intravenously	intravenously	ADV
dti-1333	86	12	,	,	PUNCT
dti-1333	86	13	fi	fi	NOUN
dti-1333	86	14	ve	ve	NOUN
dti-1333	86	15	doses	dose	NOUN
dti-1333	86	16	at	at	ADP
dti-1333	86	17	weekly	weekly	ADJ
dti-1333	86	18	intervals	interval	NOUN
dti-1333	86	19	,	,	PUNCT
dti-1333	86	20	and	and	CCONJ
dti-1333	86	21	produced	produce	VERB
dti-1333	86	22	signifi	signifi	NOUN
dti-1333	86	23	ca	can	AUX
dti-1333	86	24	nt	not	PART
dti-1333	86	25	regression	regression	VERB
dti-1333	86	26	of	of	ADP
dti-1333	86	27	coronary	coronary	ADJ
dti-1333	86	28	atherosclerosis	atherosclerosis	NOUN
dti-1333	86	29	,	,	PUNCT
dti-1333	86	30	as	as	SCONJ
dti-1333	86	31	assessed	assess	VERB
dti-1333	86	32	by	by	ADP
dti-1333	86	33	intravascular	intravascular	ADJ
dti-1333	86	34	ultrasound	ultrasound	NOUN
dti-1333	86	35	(	(	PUNCT
dti-1333	86	36	ivus	ivus	NOUN
dti-1333	86	37	)	)	PUNCT
dti-1333	86	38	.	.	PUNCT
dti-1333	87	1	remodeling	remodeling	NOUN
dti-1333	87	2	of	of	ADP
dti-1333	87	3	the	the	DET
dti-1333	87	4	arterial	arterial	ADJ
dti-1333	87	5	wall	wall	NOUN
dti-1333	87	6	was	be	AUX
dti-1333	87	7	shown	show	VERB
dti-1333	87	8	to	to	PART
dti-1333	87	9	be	be	AUX
dti-1333	87	10	a	a	DET
dti-1333	87	11	focal	focal	ADJ
dti-1333	87	12	and	and	CCONJ
dti-1333	87	13	heterogeneous	heterogeneous	ADJ
dti-1333	87	14	process	process	NOUN
dti-1333	87	15	.	.	PUNCT
dti-1333	88	1	after	after	ADP
dti-1333	88	2	infusion	infusion	NOUN
dti-1333	88	3	of	of	ADP
dti-1333	88	4	etc-216	etc-216	NOUN
dti-1333	88	5	,	,	PUNCT
dti-1333	88	6	there	there	PRON
dti-1333	88	7	was	be	VERB
dti-1333	88	8	regression	regression	NOUN
dti-1333	88	9	of	of	ADP
dti-1333	88	10	coronary	coronary	ADJ
dti-1333	88	11	atherosclerosis	atherosclerosis	NOUN
dti-1333	88	12	,	,	PUNCT
dti-1333	88	13	accompanied	accompany	VERB
dti-1333	88	14	by	by	ADP
dti-1333	88	15	reverse	reverse	ADJ
dti-1333	88	16	remodeling	remodeling	NOUN
dti-1333	88	17	of	of	ADP
dti-1333	88	18	the	the	DET
dti-1333	88	19	external	external	ADJ
dti-1333	88	20	elastic	elastic	ADJ
dti-1333	88	21	membrane	membrane	NOUN
dti-1333	88	22	,	,	PUNCT
dti-1333	88	23	with	with	ADP
dti-1333	88	24	no	no	DET
dti-1333	88	25	change	change	NOUN
dti-1333	88	26	in	in	ADP
dti-1333	88	27	luminal	luminal	ADJ
dti-1333	88	28	dimensions	dimension	NOUN
dti-1333	88	29	.	.	PUNCT
dti-1333	89	1	an	an	DET
dti-1333	89	2	average	average	ADJ
dti-1333	89	3	11	11	NUM
dti-1333	89	4	%	%	NOUN
dti-1333	89	5	reduction	reduction	NOUN
dti-1333	89	6	in	in	ADP
dti-1333	89	7	atheroma	atheroma	NOUN
dti-1333	89	8	volume	volume	NOUN
dti-1333	89	9	resulted	result	VERB
dti-1333	89	10	in	in	ADP
dti-1333	89	11	the	the	DET
dti-1333	89	12	coronary	coronary	ADJ
dti-1333	89	13	segment	segment	NOUN
dti-1333	89	14	containing	contain	VERB
dti-1333	89	15	the	the	DET
dti-1333	89	16	greatest	great	ADJ
dti-1333	89	17	atherosclerotic	atherosclerotic	ADJ
dti-1333	89	18	plaque	plaque	NOUN
dti-1333	89	19	(	(	PUNCT
dti-1333	89	20	nicholls	nicholl	NOUN
dti-1333	89	21	et	et	PROPN
dti-1333	89	22	al	al	PROPN
dti-1333	89	23	.	.	PROPN
dti-1333	89	24	2006	2006	NUM
dti-1333	89	25	)	)	PUNCT
dti-1333	89	26	.	.	PUNCT
dti-1333	90	1	in	in	ADP
dti-1333	90	2	another	another	DET
dti-1333	90	3	study	study	NOUN
dti-1333	90	4	,	,	PUNCT
dti-1333	90	5	the	the	DET
dti-1333	90	6	effects	effect	NOUN
dti-1333	90	7	of	of	ADP
dti-1333	90	8	reconstituted	reconstitute	VERB
dti-1333	90	9	hdl	hdl	NOUN
dti-1333	90	10	on	on	ADP
dti-1333	90	11	plaque	plaque	NOUN
dti-1333	90	12	burden	burden	NOUN
dti-1333	90	13	,	,	PUNCT
dti-1333	90	14	as	as	SCONJ
dti-1333	90	15	assessed	assess	VERB
dti-1333	90	16	by	by	ADP
dti-1333	90	17	ivus	ivu	NOUN
dti-1333	90	18	,	,	PUNCT
dti-1333	90	19	were	be	AUX
dti-1333	90	20	examined	examine	VERB
dti-1333	90	21	.	.	PUNCT
dti-1333	91	1	sixty	sixty	NUM
dti-1333	91	2	patients	patient	NOUN
dti-1333	91	3	received	receive	VERB
dti-1333	91	4	4	4	NUM
dti-1333	91	5	weekly	weekly	ADJ
dti-1333	91	6	infusions	infusion	NOUN
dti-1333	91	7	of	of	ADP
dti-1333	91	8	placebo	placebo	NOUN
dti-1333	91	9	(	(	PUNCT
dti-1333	91	10	saline	saline	NOUN
dti-1333	91	11	)	)	PUNCT
dti-1333	91	12	,	,	PUNCT
dti-1333	91	13	111	111	NUM
dti-1333	91	14	received	receive	VERB
dti-1333	91	15	40	40	NUM
dti-1333	91	16	mg	mg	NOUN
dti-1333	91	17	/	/	SYM
dti-1333	91	18	kg	kg	NOUN
dti-1333	91	19	of	of	ADP
dti-1333	91	20	reconstituted	reconstitute	VERB
dti-1333	91	21	hdl	hdl	PROPN
dti-1333	91	22	(	(	PUNCT
dti-1333	91	23	csl-111	csl-111	PROPN
dti-1333	91	24	)	)	PUNCT
dti-1333	91	25	,	,	PUNCT
dti-1333	91	26	and	and	CCONJ
dti-1333	91	27	12	12	NUM
dti-1333	91	28	received	receive	VERB
dti-1333	91	29	csl-111	csl-111	NOUN
dti-1333	91	30	at	at	ADP
dti-1333	91	31	80	80	NUM
dti-1333	91	32	mg	mg	PROPN
dti-1333	91	33	/	/	SYM
dti-1333	91	34	kg	kg	PROPN
dti-1333	91	35	.	.	PUNCT
dti-1333	92	1	changes	change	NOUN
dti-1333	92	2	in	in	ADP
dti-1333	92	3	atheroma	atheroma	NOUN
dti-1333	92	4	volume	volume	NOUN
dti-1333	92	5	were	be	AUX
dti-1333	92	6	assessed	assess	VERB
dti-1333	92	7	.	.	PUNCT
dti-1333	93	1	the	the	DET
dti-1333	93	2	percentage	percentage	NOUN
dti-1333	93	3	change	change	NOUN
dti-1333	93	4	in	in	ADP
dti-1333	93	5	atheroma	atheroma	NOUN
dti-1333	93	6	volume	volume	NOUN
dti-1333	93	7	was	be	AUX
dti-1333	93	8	−3.4	−3.4	NOUN
dti-1333	93	9	%	%	NOUN
dti-1333	93	10	with	with	ADP
dti-1333	93	11	csl-111	csl-111	NOUN
dti-1333	93	12	and	and	CCONJ
dti-1333	93	13	−1.6	−1.6	NOUN
dti-1333	93	14	%	%	NOUN
dti-1333	93	15	for	for	ADP
dti-1333	93	16	placebo	placebo	NOUN
dti-1333	93	17	.	.	PUNCT
dti-1333	94	1	administration	administration	NOUN
dti-1333	94	2	of	of	ADP
dti-1333	94	3	the	the	DET
dti-1333	94	4	lower	low	ADJ
dti-1333	94	5	dose	dose	NOUN
dti-1333	94	6	was	be	AUX
dti-1333	94	7	associated	associate	VERB
dti-1333	94	8	with	with	ADP
dti-1333	94	9	mild	mild	ADJ
dti-1333	94	10	,	,	PUNCT
dti-1333	94	11	self	self	NOUN
dti-1333	94	12	-	-	PUNCT
dti-1333	94	13	limiting	limit	VERB
dti-1333	94	14	transaminase	transaminase	NOUN
dti-1333	94	15	elevation	elevation	NOUN
dti-1333	94	16	,	,	PUNCT
dti-1333	94	17	but	but	CCONJ
dti-1333	94	18	was	be	AUX
dti-1333	94	19	well	well	ADV
dti-1333	94	20	tolerated	tolerate	VERB
dti-1333	94	21	.	.	PUNCT
dti-1333	95	1	short	short	ADJ
dti-1333	95	2	-	-	PUNCT
dti-1333	95	3	term	term	NOUN
dti-1333	95	4	infusion	infusion	NOUN
dti-1333	95	5	of	of	ADP
dti-1333	95	6	reconstituted	reconstitute	VERB
dti-1333	95	7	hdl	hdl	PROPN
dti-1333	95	8	resulted	result	VERB
dti-1333	95	9	in	in	ADP
dti-1333	95	10	no	no	DET
dti-1333	95	11	signifi	signifi	NOUN
dti-1333	95	12	ca	can	AUX
dti-1333	95	13	nt	not	PART
dti-1333	95	14	reduction	reduction	VERB
dti-1333	95	15	in	in	ADP
dti-1333	95	16	percentage	percentage	NOUN
dti-1333	95	17	change	change	NOUN
dti-1333	95	18	in	in	ADP
dti-1333	95	19	atheroma	atheroma	NOUN
dti-1333	95	20	volume	volume	NOUN
dti-1333	95	21	or	or	CCONJ
dti-1333	95	22	nominal	nominal	ADJ
dti-1333	95	23	change	change	NOUN
dti-1333	95	24	in	in	ADP
dti-1333	95	25	plaque	plaque	NOUN
dti-1333	95	26	volume	volume	NOUN
dti-1333	95	27	compared	compare	VERB
dti-1333	95	28	with	with	ADP
dti-1333	95	29	placebo	placebo	NOUN
dti-1333	95	30	,	,	PUNCT
dti-1333	95	31	but	but	CCONJ
dti-1333	95	32	did	do	AUX
dti-1333	95	33	result	result	VERB
dti-1333	95	34	in	in	ADP
dti-1333	95	35	statistically	statistically	ADV
dti-1333	95	36	signifi	signifi	NOUN
dti-1333	95	37	ca	can	AUX
dti-1333	95	38	nt	not	PART
dti-1333	95	39	improvement	improvement	VERB
dti-1333	95	40	in	in	ADP
dti-1333	95	41	the	the	DET
dti-1333	95	42	plaque	plaque	NOUN
dti-1333	95	43	characterization	characterization	NOUN
dti-1333	95	44	index	index	NOUN
dti-1333	95	45	and	and	CCONJ
dti-1333	95	46	coronary	coronary	ADJ
dti-1333	95	47	score	score	NOUN
dti-1333	95	48	on	on	ADP
dti-1333	95	49	quantitative	quantitative	ADJ
dti-1333	95	50	coronary	coronary	ADJ
dti-1333	95	51	angiography	angiography	NOUN
dti-1333	95	52	(	(	PUNCT
dti-1333	95	53	tardif	tardif	PROPN
dti-1333	95	54	et	et	PROPN
dti-1333	95	55	al	al	PROPN
dti-1333	95	56	.	.	PROPN
dti-1333	95	57	2007b	2007b	NUM
dti-1333	95	58	)	)	PUNCT
dti-1333	95	59	.	.	PUNCT
dti-1333	96	1	another	another	DET
dti-1333	96	2	line	line	NOUN
dti-1333	96	3	of	of	ADP
dti-1333	96	4	research	research	NOUN
dti-1333	96	5	is	be	AUX
dti-1333	96	6	the	the	DET
dti-1333	96	7	use	use	NOUN
dti-1333	96	8	of	of	ADP
dti-1333	96	9	peptides	peptide	NOUN
dti-1333	96	10	that	that	PRON
dti-1333	96	11	mimic	mimic	VERB
dti-1333	96	12	apoa	apoa	NOUN
dti-1333	96	13	-	-	PUNCT
dti-1333	96	14	i.	i.	PROPN
dti-1333	96	15	apoa	apoa	PROPN
dti-1333	96	16	-	-	PUNCT
dti-1333	96	17	i	i	PRON
dti-1333	96	18	is	be	AUX
dti-1333	96	19	a	a	DET
dti-1333	96	20	large	large	ADJ
dti-1333	96	21	protein	protein	NOUN
dti-1333	96	22	,	,	PUNCT
dti-1333	96	23	comprising	comprise	VERB
dti-1333	96	24	243	243	NUM
dti-1333	96	25	amino	amino	ADJ
dti-1333	96	26	acids	acid	NOUN
dti-1333	96	27	,	,	PUNCT
dti-1333	96	28	making	make	VERB
dti-1333	96	29	its	its	PRON
dti-1333	96	30	recombinant	recombinant	ADJ
dti-1333	96	31	preparation	preparation	NOUN
dti-1333	96	32	diffi	diffi	NOUN
dti-1333	96	33	cult	cult	NOUN
dti-1333	96	34	and	and	CCONJ
dti-1333	96	35	expensive	expensive	ADJ
dti-1333	96	36	.	.	PUNCT
dti-1333	97	1	additionally	additionally	ADV
dti-1333	97	2	,	,	PUNCT
dti-1333	97	3	intravenous	intravenous	ADJ
dti-1333	97	4	administration	administration	NOUN
dti-1333	97	5	is	be	AUX
dti-1333	97	6	necessary	necessary	ADJ
dti-1333	97	7	,	,	PUNCT
dti-1333	97	8	which	which	PRON
dti-1333	97	9	is	be	AUX
dti-1333	97	10	inconvenient	inconvenient	ADJ
dti-1333	97	11	.	.	PUNCT
dti-1333	98	1	efforts	effort	NOUN
dti-1333	98	2	have	have	AUX
dti-1333	98	3	been	be	AUX
dti-1333	98	4	made	make	VERB
dti-1333	98	5	at	at	ADP
dti-1333	98	6	fi	fi	NOUN
dti-1333	98	7	nding	nde	VERB
dti-1333	98	8	peptide	peptide	NOUN
dti-1333	98	9	mimetics	mimetic	NOUN
dti-1333	98	10	that	that	PRON
dti-1333	98	11	produce	produce	VERB
dti-1333	98	12	similar	similar	ADJ
dti-1333	98	13	results	result	NOUN
dti-1333	98	14	to	to	ADP
dti-1333	98	15	apoa	apoa	NOUN
dti-1333	98	16	-	-	PUNCT
dti-1333	98	17	i	i	PROPN
dti-1333	98	18	,	,	PUNCT
dti-1333	98	19	but	but	CCONJ
dti-1333	98	20	that	that	PRON
dti-1333	98	21	would	would	AUX
dti-1333	98	22	be	be	AUX
dti-1333	98	23	easier	easy	ADJ
dti-1333	98	24	to	to	PART
dti-1333	98	25	manufacture	manufacture	VERB
dti-1333	98	26	and	and	CCONJ
dti-1333	98	27	administer	administer	NOUN
dti-1333	98	28	(	(	PUNCT
dti-1333	98	29	pal	pal	NOUN
dti-1333	98	30	and	and	CCONJ
dti-1333	98	31	pillarisetti	pillarisetti	NOUN
dti-1333	98	32	,	,	PUNCT
dti-1333	98	33	2007	2007	NUM
dti-1333	98	34	)	)	PUNCT
dti-1333	98	35	.	.	PUNCT
dti-1333	99	1	methods	method	NOUN
dti-1333	99	2	to	to	PART
dti-1333	99	3	increase	increase	VERB
dti-1333	99	4	hdl	hdl	PROPN
dti-1333	99	5	there	there	PRON
dti-1333	99	6	is	be	VERB
dti-1333	99	7	a	a	DET
dti-1333	99	8	continuing	continue	VERB
dti-1333	99	9	need	need	NOUN
dti-1333	99	10	for	for	ADP
dti-1333	99	11	novel	novel	ADJ
dti-1333	99	12	therapies	therapy	NOUN
dti-1333	99	13	that	that	PRON
dti-1333	99	14	increase	increase	VERB
dti-1333	99	15	the	the	DET
dti-1333	99	16	biosynthesis	biosynthesis	NOUN
dti-1333	99	17	of	of	ADP
dti-1333	99	18	hdl	hdl	NOUN
dti-1333	99	19	,	,	PUNCT
dti-1333	99	20	to	to	PART
dti-1333	99	21	inhibit	inhibit	VERB
dti-1333	99	22	the	the	DET
dti-1333	99	23	49	49	NUM
dti-1333	99	24	therapies	therapy	NOUN
dti-1333	99	25	to	to	PART
dti-1333	99	26	increase	increase	VERB
dti-1333	99	27	apoa-1	apoa-1	NUM
dti-1333	99	28	and	and	CCONJ
dti-1333	99	29	hdl	hdl	PROPN
dti-1333	99	30	-	-	PUNCT
dti-1333	99	31	cholesterol	cholesterol	NOUN
dti-1333	99	32	levels	level	NOUN
dti-1333	99	33	drug	drug	NOUN
dti-1333	99	34	target	target	NOUN
dti-1333	99	35	insights	insight	VERB
dti-1333	99	36	2008:3	2008:3	NUM
dti-1333	99	37	progression	progression	NOUN
dti-1333	99	38	of	of	ADP
dti-1333	99	39	and	and	CCONJ
dti-1333	99	40	even	even	ADV
dti-1333	99	41	bring	bring	VERB
dti-1333	99	42	about	about	ADP
dti-1333	99	43	regression	regression	NOUN
dti-1333	99	44	of	of	ADP
dti-1333	99	45	atherosclerosis	atherosclerosis	NOUN
dti-1333	99	46	.	.	PUNCT
dti-1333	100	1	the	the	DET
dti-1333	100	2	development	development	NOUN
dti-1333	100	3	of	of	ADP
dti-1333	100	4	a	a	DET
dti-1333	100	5	small	small	ADJ
dti-1333	100	6	molecule	molecule	NOUN
dti-1333	100	7	drug	drug	NOUN
dti-1333	100	8	that	that	PRON
dti-1333	100	9	increases	increase	VERB
dti-1333	100	10	endogenous	endogenous	ADJ
dti-1333	100	11	apoa	apoa	NOUN
dti-1333	100	12	-	-	PUNCT
dti-1333	100	13	i	i	PRON
dti-1333	100	14	could	could	AUX
dti-1333	100	15	provide	provide	VERB
dti-1333	100	16	a	a	DET
dti-1333	100	17	breakthrough	breakthrough	NOUN
dti-1333	100	18	therapy	therapy	NOUN
dti-1333	100	19	for	for	ADP
dti-1333	100	20	treating	treat	VERB
dti-1333	100	21	cardiovascular	cardiovascular	ADJ
dti-1333	100	22	disease	disease	NOUN
dti-1333	100	23	,	,	PUNCT
dti-1333	100	24	either	either	CCONJ
dti-1333	100	25	as	as	ADP
dti-1333	100	26	a	a	DET
dti-1333	100	27	stand	stand	VERB
dti-1333	100	28	-	-	PUNCT
dti-1333	100	29	alone	alone	ADJ
dti-1333	100	30	treatment	treatment	NOUN
dti-1333	100	31	or	or	CCONJ
dti-1333	100	32	in	in	ADP
dti-1333	100	33	combination	combination	NOUN
dti-1333	100	34	.	.	PUNCT
dti-1333	101	1	the	the	DET
dti-1333	101	2	parallels	parallel	NOUN
dti-1333	101	3	with	with	ADP
dti-1333	101	4	apoa	apoa	NOUN
dti-1333	101	5	-	-	PUNCT
dti-1333	101	6	i	i	PROPN
dti-1333	101	7	infusion	infusion	NOUN
dti-1333	101	8	therapy	therapy	NOUN
dti-1333	101	9	are	be	AUX
dti-1333	101	10	clear	clear	ADJ
dti-1333	101	11	;	;	PUNCT
dti-1333	101	12	while	while	SCONJ
dti-1333	101	13	infusion	infusion	NOUN
dti-1333	101	14	therapies	therapy	NOUN
dti-1333	101	15	may	may	AUX
dti-1333	101	16	be	be	AUX
dti-1333	101	17	appropriate	appropriate	ADJ
dti-1333	101	18	for	for	ADP
dti-1333	101	19	short	short	ADJ
dti-1333	101	20	-	-	PUNCT
dti-1333	101	21	term	term	NOUN
dti-1333	101	22	treatment	treatment	NOUN
dti-1333	101	23	,	,	PUNCT
dti-1333	101	24	a	a	DET
dti-1333	101	25	small	small	ADJ
dti-1333	101	26	molecule	molecule	NOUN
dti-1333	101	27	approach	approach	NOUN
dti-1333	101	28	could	could	AUX
dti-1333	101	29	provide	provide	VERB
dti-1333	101	30	a	a	DET
dti-1333	101	31	long	long	ADJ
dti-1333	101	32	-	-	PUNCT
dti-1333	101	33	term	term	NOUN
dti-1333	101	34	increase	increase	NOUN
dti-1333	101	35	in	in	ADP
dti-1333	101	36	apoa	apoa	NOUN
dti-1333	101	37	-	-	PUNCT
dti-1333	101	38	i	i	PROPN
dti-1333	101	39	,	,	PUNCT
dti-1333	101	40	by	by	ADP
dti-1333	101	41	chronic	chronic	ADJ
dti-1333	101	42	treatment	treatment	NOUN
dti-1333	101	43	.	.	PUNCT
dti-1333	102	1	targeting	target	VERB
dti-1333	102	2	the	the	DET
dti-1333	102	3	patient	patient	NOUN
dti-1333	102	4	’s	’s	PART
dti-1333	102	5	liver	liver	NOUN
dti-1333	102	6	and	and	CCONJ
dti-1333	102	7	small	small	ADJ
dti-1333	102	8	intestine	intestine	NOUN
dti-1333	102	9	to	to	PART
dti-1333	102	10	increase	increase	VERB
dti-1333	102	11	the	the	DET
dti-1333	102	12	transcription	transcription	NOUN
dti-1333	102	13	,	,	PUNCT
dti-1333	102	14	synthesis	synthesis	NOUN
dti-1333	102	15	,	,	PUNCT
dti-1333	102	16	and	and	CCONJ
dti-1333	102	17	secretion	secretion	NOUN
dti-1333	102	18	of	of	ADP
dti-1333	102	19	apoa	apoa	NOUN
dti-1333	102	20	-	-	PUNCT
dti-1333	102	21	i	i	PRON
dti-1333	102	22	is	be	AUX
dti-1333	102	23	generally	generally	ADV
dti-1333	102	24	considered	consider	VERB
dti-1333	102	25	to	to	PART
dti-1333	102	26	be	be	AUX
dti-1333	102	27	a	a	DET
dti-1333	102	28	promising	promising	ADJ
dti-1333	102	29	approach	approach	NOUN
dti-1333	102	30	to	to	ADP
dti-1333	102	31	raising	raise	VERB
dti-1333	102	32	hdl	hdl	PROPN
dti-1333	102	33	-	-	PUNCT
dti-1333	102	34	c	c	PROPN
dti-1333	102	35	levels	level	NOUN
dti-1333	102	36	(	(	PUNCT
dti-1333	102	37	rader	rader	NOUN
dti-1333	102	38	,	,	PUNCT
dti-1333	102	39	2006	2006	NUM
dti-1333	102	40	,	,	PUNCT
dti-1333	102	41	2007a	2007a	NUM
dti-1333	102	42	,	,	PUNCT
dti-1333	102	43	2007b	2007b	NUM
dti-1333	102	44	;	;	PUNCT
dti-1333	102	45	toth	toth	PROPN
dti-1333	102	46	,	,	PUNCT
dti-1333	102	47	2007	2007	NUM
dti-1333	102	48	;	;	PUNCT
dti-1333	102	49	nicholls	nicholls	PROPN
dti-1333	102	50	and	and	CCONJ
dti-1333	102	51	nissen	nissen	PROPN
dti-1333	102	52	,	,	PUNCT
dti-1333	102	53	2007	2007	NUM
dti-1333	102	54	;	;	PUNCT
dti-1333	102	55	but	but	CCONJ
dti-1333	102	56	see	see	VERB
dti-1333	102	57	singh	singh	PROPN
dti-1333	102	58	et	et	PROPN
dti-1333	102	59	al	al	PROPN
dti-1333	102	60	.	.	PROPN
dti-1333	102	61	2007	2007	NUM
dti-1333	102	62	)	)	PUNCT
dti-1333	102	63	.	.	PUNCT
dti-1333	103	1	much	much	ADJ
dti-1333	103	2	is	be	AUX
dti-1333	103	3	now	now	ADV
dti-1333	103	4	known	know	VERB
dti-1333	103	5	about	about	ADP
dti-1333	103	6	the	the	DET
dti-1333	103	7	regulatory	regulatory	ADJ
dti-1333	103	8	sequences	sequence	NOUN
dti-1333	103	9	and	and	CCONJ
dti-1333	103	10	transcription	transcription	NOUN
dti-1333	103	11	factors	factor	NOUN
dti-1333	103	12	in	in	ADP
dti-1333	103	13	the	the	DET
dti-1333	103	14	liver	liver	NOUN
dti-1333	103	15	and	and	CCONJ
dti-1333	103	16	small	small	ADJ
dti-1333	103	17	intestine	intestine	NOUN
dti-1333	103	18	that	that	PRON
dti-1333	103	19	control	control	NOUN
dti-1333	103	20	apoa	apoa	PROPN
dti-1333	103	21	-	-	PUNCT
dti-1333	103	22	i	i	PRON
dti-1333	103	23	transcription	transcription	NOUN
dti-1333	103	24	.	.	PUNCT
dti-1333	104	1	the	the	DET
dti-1333	104	2	human	human	ADJ
dti-1333	104	3	gene	gene	NOUN
dti-1333	104	4	encoding	encoding	NOUN
dti-1333	104	5	apoa	apoa	NOUN
dti-1333	104	6	-	-	PUNCT
dti-1333	104	7	i	i	PRON
dti-1333	104	8	resides	reside	VERB
dti-1333	104	9	in	in	ADP
dti-1333	104	10	an	an	DET
dti-1333	104	11	apoa	apoa	NOUN
dti-1333	104	12	-	-	PUNCT
dti-1333	104	13	i	i	NOUN
dti-1333	104	14	-	-	PUNCT
dti-1333	104	15	ciii	ciii	NOUN
dti-1333	104	16	-	-	PUNCT
dti-1333	104	17	aiv	aiv	NOUN
dti-1333	104	18	gene	gene	NOUN
dti-1333	104	19	cluster	cluster	NOUN
dti-1333	104	20	,	,	PUNCT
dti-1333	104	21	located	locate	VERB
dti-1333	104	22	at	at	ADP
dti-1333	104	23	chromosome	chromosome	NOUN
dti-1333	104	24	11q23	11q23	NOUN
dti-1333	104	25	-	-	NOUN
dti-1333	104	26	q24	q24	NOUN
dti-1333	104	27	(	(	PUNCT
dti-1333	104	28	lai	lai	PROPN
dti-1333	104	29	et	et	PROPN
dti-1333	104	30	al	al	PROPN
dti-1333	104	31	.	.	PROPN
dti-1333	104	32	2005	2005	NUM
dti-1333	104	33	)	)	PUNCT
dti-1333	104	34	.	.	PUNCT
dti-1333	105	1	the	the	DET
dti-1333	105	2	proximal	proximal	ADJ
dti-1333	105	3	apoa	apoa	NOUN
dti-1333	105	4	-	-	PUNCT
dti-1333	105	5	i	i	PROPN
dti-1333	105	6	promoter	promoter	NOUN
dti-1333	105	7	and	and	CCONJ
dti-1333	105	8	enhancer	enhancer	NOUN
dti-1333	105	9	contains	contain	VERB
dti-1333	105	10	multiple	multiple	ADJ
dti-1333	105	11	cis	cis	NOUN
dti-1333	105	12	-	-	PUNCT
dti-1333	105	13	acting	act	VERB
dti-1333	105	14	regulatory	regulatory	ADJ
dti-1333	105	15	elements	element	NOUN
dti-1333	105	16	to	to	PART
dti-1333	105	17	which	which	PRON
dti-1333	105	18	various	various	ADJ
dti-1333	105	19	hepatocyte	hepatocyte	NOUN
dti-1333	105	20	-	-	PUNCT
dti-1333	105	21	specifi	specifi	PROPN
dti-1333	105	22	c	c	PROPN
dti-1333	105	23	and	and	CCONJ
dti-1333	105	24	ubiquitous	ubiquitous	ADJ
dti-1333	105	25	transcription	transcription	NOUN
dti-1333	105	26	factors	factor	NOUN
dti-1333	105	27	bind	bind	VERB
dti-1333	105	28	to	to	PART
dti-1333	105	29	regulate	regulate	VERB
dti-1333	105	30	liver	liver	NOUN
dti-1333	105	31	-	-	PUNCT
dti-1333	105	32	specifi	specifi	NOUN
dti-1333	105	33	c	c	PROPN
dti-1333	105	34	transcription	transcription	NOUN
dti-1333	105	35	,	,	PUNCT
dti-1333	105	36	while	while	SCONJ
dti-1333	105	37	expression	expression	NOUN
dti-1333	105	38	in	in	ADP
dti-1333	105	39	intestinal	intestinal	ADJ
dti-1333	105	40	cells	cell	NOUN
dti-1333	105	41	requires	require	VERB
dti-1333	105	42	the	the	DET
dti-1333	105	43	apociii	apociii	ADJ
dti-1333	105	44	promoter	promoter	NOUN
dti-1333	105	45	region	region	NOUN
dti-1333	105	46	(	(	PUNCT
dti-1333	105	47	walsh	walsh	PROPN
dti-1333	105	48	et	et	PROPN
dti-1333	105	49	al	al	PROPN
dti-1333	105	50	.	.	PROPN
dti-1333	105	51	1993	1993	NUM
dti-1333	105	52	;	;	PUNCT
dti-1333	105	53	zannis	zannis	X
dti-1333	105	54	et	et	PROPN
dti-1333	105	55	al	al	PROPN
dti-1333	105	56	.	.	PROPN
dti-1333	105	57	2001	2001	NUM
dti-1333	105	58	)	)	PUNCT
dti-1333	105	59	.	.	PUNCT
dti-1333	106	1	despite	despite	SCONJ
dti-1333	106	2	strong	strong	ADJ
dti-1333	106	3	evidence	evidence	NOUN
dti-1333	106	4	connecting	connect	VERB
dti-1333	106	5	hdl	hdl	NOUN
dti-1333	106	6	to	to	ADP
dti-1333	106	7	cardiovascular	cardiovascular	ADJ
dti-1333	106	8	disease	disease	NOUN
dti-1333	106	9	,	,	PUNCT
dti-1333	106	10	there	there	PRON
dti-1333	106	11	are	be	VERB
dti-1333	106	12	currently	currently	ADV
dti-1333	106	13	no	no	DET
dti-1333	106	14	potent	potent	ADJ
dti-1333	106	15	hdl	hdl	PROPN
dti-1333	106	16	elevators	elevator	NOUN
dti-1333	106	17	available	available	ADJ
dti-1333	106	18	.	.	PUNCT
dti-1333	107	1	existing	exist	VERB
dti-1333	107	2	methods	method	NOUN
dti-1333	107	3	of	of	ADP
dti-1333	107	4	increasing	increase	VERB
dti-1333	107	5	hdl	hdl	PROPN
dti-1333	107	6	-	-	PUNCT
dti-1333	107	7	c	c	PROPN
dti-1333	107	8	include	include	VERB
dti-1333	107	9	life	life	NOUN
dti-1333	107	10	style	style	NOUN
dti-1333	107	11	changes	change	NOUN
dti-1333	107	12	,	,	PUNCT
dti-1333	107	13	niacin	niacin	NOUN
dti-1333	107	14	,	,	PUNCT
dti-1333	107	15	fi	fi	NOUN
dti-1333	107	16	brates	brate	NOUN
dti-1333	107	17	,	,	PUNCT
dti-1333	107	18	estrogen	estrogen	NOUN
dti-1333	107	19	,	,	PUNCT
dti-1333	107	20	and	and	CCONJ
dti-1333	107	21	to	to	ADP
dti-1333	107	22	some	some	DET
dti-1333	107	23	degree	degree	NOUN
dti-1333	107	24	,	,	PUNCT
dti-1333	107	25	the	the	DET
dti-1333	107	26	statins	statin	NOUN
dti-1333	107	27	.	.	PUNCT
dti-1333	108	1	life	life	NOUN
dti-1333	108	2	style	style	PROPN
dti-1333	108	3	modifi	modifi	NOUN
dti-1333	108	4	cation	cation	NOUN
dti-1333	108	5	can	can	AUX
dti-1333	108	6	increase	increase	VERB
dti-1333	108	7	serum	serum	NOUN
dti-1333	108	8	levels	level	NOUN
dti-1333	108	9	by	by	ADP
dti-1333	108	10	5%–15	5%–15	NUM
dti-1333	108	11	%	%	NOUN
dti-1333	108	12	,	,	PUNCT
dti-1333	108	13	while	while	SCONJ
dti-1333	108	14	niacin	niacin	NOUN
dti-1333	108	15	,	,	PUNCT
dti-1333	108	16	the	the	DET
dti-1333	108	17	drug	drug	NOUN
dti-1333	108	18	most	most	ADV
dti-1333	108	19	widely	widely	ADV
dti-1333	108	20	used	use	VERB
dti-1333	108	21	to	to	PART
dti-1333	108	22	increase	increase	VERB
dti-1333	108	23	hdl	hdl	X
dti-1333	108	24	-	-	PUNCT
dti-1333	108	25	c	c	PROPN
dti-1333	108	26	,	,	PUNCT
dti-1333	108	27	can	can	AUX
dti-1333	108	28	increase	increase	VERB
dti-1333	108	29	it	it	PRON
dti-1333	108	30	by	by	ADP
dti-1333	108	31	25%–35	25%–35	NUM
dti-1333	108	32	%	%	NOUN
dti-1333	108	33	at	at	ADP
dti-1333	108	34	the	the	DET
dti-1333	108	35	highest	high	ADJ
dti-1333	108	36	doses	dose	NOUN
dti-1333	108	37	,	,	PUNCT
dti-1333	108	38	fi	fi	NOUN
dti-1333	108	39	brates	brate	NOUN
dti-1333	108	40	increase	increase	VERB
dti-1333	108	41	hdl	hdl	NOUN
dti-1333	108	42	-	-	PUNCT
dti-1333	108	43	c	c	PROPN
dti-1333	108	44	by	by	ADP
dti-1333	108	45	10%–25	10%–25	NUM
dti-1333	108	46	%	%	NOUN
dti-1333	108	47	,	,	PUNCT
dti-1333	108	48	and	and	CCONJ
dti-1333	108	49	statins	statin	NOUN
dti-1333	108	50	by	by	ADP
dti-1333	108	51	5%–15	5%–15	NUM
dti-1333	108	52	%	%	NOUN
dti-1333	108	53	at	at	ADP
dti-1333	108	54	moderate	moderate	ADJ
dti-1333	108	55	doses	dose	NOUN
dti-1333	108	56	.	.	PUNCT
dti-1333	109	1	life	life	NOUN
dti-1333	109	2	style	style	NOUN
dti-1333	109	3	modifi	modifi	NOUN
dti-1333	109	4	cation	cation	NOUN
dti-1333	109	5	much	much	ADJ
dti-1333	109	6	research	research	NOUN
dti-1333	109	7	suggests	suggest	VERB
dti-1333	109	8	that	that	SCONJ
dti-1333	109	9	the	the	DET
dti-1333	109	10	first	first	ADJ
dti-1333	109	11	step	step	NOUN
dti-1333	109	12	in	in	ADP
dti-1333	109	13	increasing	increase	VERB
dti-1333	109	14	hdl	hdl	PROPN
dti-1333	109	15	-	-	PUNCT
dti-1333	109	16	c	c	PROPN
dti-1333	109	17	levels	level	NOUN
dti-1333	109	18	should	should	AUX
dti-1333	109	19	be	be	AUX
dti-1333	109	20	life	life	NOUN
dti-1333	109	21	style	style	NOUN
dti-1333	109	22	modifi	modifi	NOUN
dti-1333	109	23	cation	cation	NOUN
dti-1333	109	24	.	.	PUNCT
dti-1333	110	1	regular	regular	ADJ
dti-1333	110	2	aerobic	aerobic	ADJ
dti-1333	110	3	exercise	exercise	NOUN
dti-1333	110	4	,	,	PUNCT
dti-1333	110	5	loss	loss	NOUN
dti-1333	110	6	of	of	ADP
dti-1333	110	7	excess	excess	ADJ
dti-1333	110	8	weight	weight	NOUN
dti-1333	110	9	(	(	PUNCT
dti-1333	110	10	fat	fat	NOUN
dti-1333	110	11	)	)	PUNCT
dti-1333	110	12	,	,	PUNCT
dti-1333	110	13	cessation	cessation	NOUN
dti-1333	110	14	of	of	ADP
dti-1333	110	15	cigarette	cigarette	NOUN
dti-1333	110	16	smoking	smoking	NOUN
dti-1333	110	17	,	,	PUNCT
dti-1333	110	18	and	and	CCONJ
dti-1333	110	19	changes	change	NOUN
dti-1333	110	20	in	in	ADP
dti-1333	110	21	diet	diet	NOUN
dti-1333	110	22	can	can	AUX
dti-1333	110	23	all	all	PRON
dti-1333	110	24	increase	increase	VERB
dti-1333	110	25	hdl	hdl	PROPN
dti-1333	110	26	-	-	PUNCT
dti-1333	110	27	c	c	PROPN
dti-1333	110	28	levels	level	NOUN
dti-1333	110	29	(	(	PUNCT
dti-1333	110	30	ashen	ashen	ADJ
dti-1333	110	31	and	and	CCONJ
dti-1333	110	32	blumenthal	blumenthal	PROPN
dti-1333	110	33	,	,	PUNCT
dti-1333	110	34	2005	2005	NUM
dti-1333	110	35	;	;	PUNCT
dti-1333	110	36	kodama	kodama	PROPN
dti-1333	110	37	et	et	PROPN
dti-1333	110	38	al	al	PROPN
dti-1333	110	39	.	.	PROPN
dti-1333	110	40	2007	2007	NUM
dti-1333	110	41	;	;	PUNCT
dti-1333	110	42	mooradian	mooradian	PROPN
dti-1333	110	43	et	et	PROPN
dti-1333	110	44	al	al	PROPN
dti-1333	110	45	.	.	PROPN
dti-1333	110	46	2006	2006	NUM
dti-1333	110	47	;	;	PUNCT
dti-1333	110	48	dullens	dullen	VERB
dti-1333	110	49	et	et	PROPN
dti-1333	110	50	al	al	PROPN
dti-1333	110	51	.	.	PROPN
dti-1333	110	52	2007	2007	NUM
dti-1333	110	53	)	)	PUNCT
dti-1333	110	54	.	.	PUNCT
dti-1333	111	1	dietary	dietary	ADJ
dti-1333	111	2	soy	soy	NOUN
dti-1333	111	3	protein	protein	NOUN
dti-1333	111	4	,	,	PUNCT
dti-1333	111	5	soluble	soluble	ADJ
dti-1333	111	6	fi	fi	NOUN
dti-1333	111	7	ber	ber	NOUN
dti-1333	111	8	,	,	PUNCT
dti-1333	111	9	and	and	CCONJ
dti-1333	111	10	plant	plant	VERB
dti-1333	111	11	sterol/	sterol/	ADJ
dti-1333	111	12	ester	ester	NOUN
dti-1333	111	13	-	-	PUNCT
dti-1333	111	14	containing	contain	VERB
dti-1333	111	15	margarines	margarine	NOUN
dti-1333	111	16	have	have	AUX
dti-1333	111	17	all	all	PRON
dti-1333	111	18	been	be	AUX
dti-1333	111	19	shown	show	VERB
dti-1333	111	20	to	to	PART
dti-1333	111	21	favorably	favorably	ADV
dti-1333	111	22	increase	increase	VERB
dti-1333	111	23	the	the	DET
dti-1333	111	24	ldl	ldl	NOUN
dti-1333	111	25	:	:	PUNCT
dti-1333	111	26	hdl	hdl	PROPN
dti-1333	111	27	ratio	ratio	PROPN
dti-1333	111	28	(	(	PUNCT
dti-1333	111	29	hermansen	hermansen	VERB
dti-1333	111	30	et	et	PROPN
dti-1333	111	31	al	al	PROPN
dti-1333	111	32	.	.	PROPN
dti-1333	111	33	2003	2003	NUM
dti-1333	111	34	)	)	PUNCT
dti-1333	111	35	.	.	PUNCT
dti-1333	112	1	diets	diet	NOUN
dti-1333	112	2	rich	rich	ADJ
dti-1333	112	3	in	in	ADP
dti-1333	112	4	wholegrain	wholegrain	NOUN
dti-1333	112	5	foods	food	NOUN
dti-1333	112	6	tend	tend	VERB
dti-1333	112	7	to	to	PART
dti-1333	112	8	increase	increase	VERB
dti-1333	112	9	serum	serum	NOUN
dti-1333	112	10	hdl	hdl	PROPN
dti-1333	112	11	-	-	PUNCT
dti-1333	112	12	c	c	NOUN
dti-1333	112	13	levels	level	NOUN
dti-1333	112	14	,	,	PUNCT
dti-1333	112	15	while	while	SCONJ
dti-1333	112	16	decreasing	decrease	VERB
dti-1333	112	17	serum	serum	NOUN
dti-1333	112	18	ldl	ldl	NOUN
dti-1333	112	19	-	-	PUNCT
dti-1333	112	20	c	c	NOUN
dti-1333	112	21	,	,	PUNCT
dti-1333	112	22	triacylglycerol	triacylglycerol	NOUN
dti-1333	112	23	levels	level	NOUN
dti-1333	112	24	,	,	PUNCT
dti-1333	112	25	and	and	CCONJ
dti-1333	112	26	blood	blood	NOUN
dti-1333	112	27	pressure	pressure	NOUN
dti-1333	112	28	(	(	PUNCT
dti-1333	112	29	anderson	anderson	PROPN
dti-1333	112	30	,	,	PUNCT
dti-1333	112	31	2003	2003	NUM
dti-1333	112	32	)	)	PUNCT
dti-1333	112	33	.	.	PUNCT
dti-1333	113	1	the	the	DET
dti-1333	113	2	effects	effect	NOUN
dti-1333	113	3	of	of	ADP
dti-1333	113	4	soy	soy	NOUN
dti-1333	113	5	isofl	isofl	NOUN
dti-1333	113	6	avones	avone	NOUN
dti-1333	113	7	are	be	AUX
dti-1333	113	8	somewhat	somewhat	ADV
dti-1333	113	9	controversial	controversial	ADJ
dti-1333	113	10	(	(	PUNCT
dti-1333	113	11	see	see	INTJ
dti-1333	113	12	dullens	dullen	NOUN
dti-1333	113	13	et	et	PROPN
dti-1333	113	14	al	al	PROPN
dti-1333	113	15	.	.	PROPN
dti-1333	113	16	2007	2007	NUM
dti-1333	113	17	)	)	PUNCT
dti-1333	113	18	.	.	PUNCT
dti-1333	114	1	polyphenols	polyphenol	NOUN
dti-1333	114	2	have	have	AUX
dti-1333	114	3	become	become	VERB
dti-1333	114	4	a	a	DET
dti-1333	114	5	focus	focus	NOUN
dti-1333	114	6	of	of	ADP
dti-1333	114	7	research	research	NOUN
dti-1333	114	8	for	for	ADP
dti-1333	114	9	their	their	PRON
dti-1333	114	10	role	role	NOUN
dti-1333	114	11	in	in	ADP
dti-1333	114	12	the	the	DET
dti-1333	114	13	prevention	prevention	NOUN
dti-1333	114	14	of	of	ADP
dti-1333	114	15	cardiovascular	cardiovascular	ADJ
dti-1333	114	16	disease	disease	NOUN
dti-1333	114	17	and	and	CCONJ
dti-1333	114	18	ability	ability	NOUN
dti-1333	114	19	to	to	PART
dti-1333	114	20	raise	raise	VERB
dti-1333	114	21	hdl	hdl	PROPN
dti-1333	114	22	-	-	PUNCT
dti-1333	114	23	c.	c.	NOUN
dti-1333	114	24	polyphenols	polyphenol	NOUN
dti-1333	114	25	are	be	AUX
dti-1333	114	26	common	common	ADJ
dti-1333	114	27	components	component	NOUN
dti-1333	114	28	of	of	ADP
dti-1333	114	29	the	the	DET
dti-1333	114	30	human	human	ADJ
dti-1333	114	31	diet	diet	NOUN
dti-1333	114	32	,	,	PUNCT
dti-1333	114	33	present	present	ADJ
dti-1333	114	34	in	in	ADP
dti-1333	114	35	many	many	ADJ
dti-1333	114	36	foods	food	NOUN
dti-1333	114	37	and	and	CCONJ
dti-1333	114	38	beverages	beverage	NOUN
dti-1333	114	39	of	of	ADP
dti-1333	114	40	plant	plant	NOUN
dti-1333	114	41	origin	origin	NOUN
dti-1333	114	42	,	,	PUNCT
dti-1333	114	43	including	include	VERB
dti-1333	114	44	tea	tea	NOUN
dti-1333	114	45	,	,	PUNCT
dti-1333	114	46	wine	wine	NOUN
dti-1333	114	47	,	,	PUNCT
dti-1333	114	48	cocoa	cocoa	NOUN
dti-1333	114	49	,	,	PUNCT
dti-1333	114	50	and	and	CCONJ
dti-1333	114	51	soy	soy	NOUN
dti-1333	114	52	.	.	PROPN
dti-1333	114	53	epidemiological	epidemiological	ADJ
dti-1333	114	54	studies	study	NOUN
dti-1333	114	55	have	have	AUX
dti-1333	114	56	repeatedly	repeatedly	ADV
dti-1333	114	57	shown	show	VERB
dti-1333	114	58	an	an	DET
dti-1333	114	59	inverse	inverse	NOUN
dti-1333	114	60	association	association	NOUN
dti-1333	114	61	between	between	ADP
dti-1333	114	62	the	the	DET
dti-1333	114	63	risk	risk	NOUN
dti-1333	114	64	of	of	ADP
dti-1333	114	65	myocardial	myocardial	ADJ
dti-1333	114	66	infarction	infarction	NOUN
dti-1333	114	67	and	and	CCONJ
dti-1333	114	68	the	the	DET
dti-1333	114	69	consumption	consumption	NOUN
dti-1333	114	70	of	of	ADP
dti-1333	114	71	tea	tea	NOUN
dti-1333	114	72	or	or	CCONJ
dti-1333	114	73	wine	wine	NOUN
dti-1333	114	74	and	and	CCONJ
dti-1333	114	75	intake	intake	NOUN
dti-1333	114	76	levels	level	NOUN
dti-1333	114	77	of	of	ADP
dti-1333	114	78	some	some	DET
dti-1333	114	79	particular	particular	ADJ
dti-1333	114	80	fl	fl	NOUN
dti-1333	114	81	avonoids	avonoid	NOUN
dti-1333	114	82	,	,	PUNCT
dti-1333	114	83	but	but	CCONJ
dti-1333	114	84	no	no	DET
dti-1333	114	85	clear	clear	ADJ
dti-1333	114	86	association	association	NOUN
dti-1333	114	87	has	have	AUX
dti-1333	114	88	been	be	AUX
dti-1333	114	89	found	find	VERB
dti-1333	114	90	in	in	ADP
dti-1333	114	91	clinical	clinical	ADJ
dti-1333	114	92	studies	study	NOUN
dti-1333	114	93	with	with	ADP
dti-1333	114	94	primary	primary	ADJ
dti-1333	114	95	clinical	clinical	ADJ
dti-1333	114	96	endpoints	endpoint	NOUN
dti-1333	114	97	(	(	PUNCT
dti-1333	114	98	scalbert	scalbert	PROPN
dti-1333	114	99	et	et	PROPN
dti-1333	114	100	al	al	PROPN
dti-1333	114	101	.	.	PROPN
dti-1333	114	102	2005	2005	NUM
dti-1333	114	103	;	;	PUNCT
dti-1333	114	104	manach	manach	ADV
dti-1333	114	105	et	et	PROPN
dti-1333	114	106	al	al	PROPN
dti-1333	114	107	.	.	PROPN
dti-1333	114	108	2005	2005	NUM
dti-1333	114	109	)	)	PUNCT
dti-1333	114	110	.	.	PUNCT
dti-1333	115	1	in	in	ADP
dti-1333	115	2	fact	fact	NOUN
dti-1333	115	3	,	,	PUNCT
dti-1333	115	4	in	in	ADP
dti-1333	115	5	twelve	twelve	NUM
dti-1333	115	6	intervention	intervention	NOUN
dti-1333	115	7	studies	study	NOUN
dti-1333	115	8	with	with	ADP
dti-1333	115	9	differing	differ	VERB
dti-1333	115	10	polyphenol	polyphenol	NOUN
dti-1333	115	11	sources	source	NOUN
dti-1333	115	12	,	,	PUNCT
dti-1333	115	13	six	six	NUM
dti-1333	115	14	showed	show	VERB
dti-1333	115	15	no	no	DET
dti-1333	115	16	effect	effect	NOUN
dti-1333	115	17	on	on	ADP
dti-1333	115	18	lipid	lipid	ADJ
dti-1333	115	19	parameters	parameter	NOUN
dti-1333	115	20	and	and	CCONJ
dti-1333	115	21	six	six	NUM
dti-1333	115	22	showed	show	VERB
dti-1333	115	23	an	an	DET
dti-1333	115	24	improvement	improvement	NOUN
dti-1333	115	25	(	(	PUNCT
dti-1333	115	26	manach	manach	NOUN
dti-1333	115	27	et	et	PROPN
dti-1333	115	28	al	al	PROPN
dti-1333	115	29	.	.	PROPN
dti-1333	115	30	2005	2005	NUM
dti-1333	115	31	)	)	PUNCT
dti-1333	115	32	.	.	PUNCT
dti-1333	116	1	such	such	ADJ
dti-1333	116	2	inconclusive	inconclusive	ADJ
dti-1333	116	3	data	datum	NOUN
dti-1333	116	4	has	have	AUX
dti-1333	116	5	clouded	cloud	VERB
dti-1333	116	6	the	the	DET
dti-1333	116	7	use	use	NOUN
dti-1333	116	8	of	of	ADP
dti-1333	116	9	polyphenols	polyphenol	NOUN
dti-1333	116	10	(	(	PUNCT
dti-1333	116	11	zern	zern	NOUN
dti-1333	116	12	and	and	CCONJ
dti-1333	116	13	fernandez	fernandez	PROPN
dti-1333	116	14	,	,	PUNCT
dti-1333	116	15	2005	2005	NUM
dti-1333	116	16	)	)	PUNCT
dti-1333	116	17	.	.	PUNCT
dti-1333	117	1	moderate	moderate	ADJ
dti-1333	117	2	consumption	consumption	NOUN
dti-1333	117	3	of	of	ADP
dti-1333	117	4	red	red	ADJ
dti-1333	117	5	wine	wine	NOUN
dti-1333	117	6	(	(	PUNCT
dti-1333	117	7	one	one	NUM
dti-1333	117	8	or	or	CCONJ
dti-1333	117	9	two	two	NUM
dti-1333	117	10	drinks	drink	NOUN
dti-1333	117	11	per	per	ADP
dti-1333	117	12	day	day	NOUN
dti-1333	117	13	)	)	PUNCT
dti-1333	117	14	has	have	AUX
dti-1333	117	15	consistently	consistently	ADV
dti-1333	117	16	been	be	AUX
dti-1333	117	17	associated	associate	VERB
dti-1333	117	18	with	with	ADP
dti-1333	117	19	a	a	DET
dti-1333	117	20	reduced	reduced	ADJ
dti-1333	117	21	risk	risk	NOUN
dti-1333	117	22	of	of	ADP
dti-1333	117	23	cardiovascular	cardiovascular	ADJ
dti-1333	117	24	diseases	disease	NOUN
dti-1333	117	25	.	.	PUNCT
dti-1333	118	1	this	this	DET
dti-1333	118	2	phenomenon	phenomenon	NOUN
dti-1333	118	3	has	have	AUX
dti-1333	118	4	been	be	AUX
dti-1333	118	5	used	use	VERB
dti-1333	118	6	to	to	PART
dti-1333	118	7	explain	explain	VERB
dti-1333	118	8	the	the	DET
dti-1333	118	9	so	so	ADV
dti-1333	118	10	-	-	PUNCT
dti-1333	118	11	called	call	VERB
dti-1333	118	12	“	"	PUNCT
dti-1333	118	13	french	french	ADJ
dti-1333	118	14	paradox	paradox	NOUN
dti-1333	118	15	,	,	PUNCT
dti-1333	118	16	”	"	PUNCT
dti-1333	118	17	the	the	DET
dti-1333	118	18	relatively	relatively	ADV
dti-1333	118	19	low	low	ADJ
dti-1333	118	20	rate	rate	NOUN
dti-1333	118	21	of	of	ADP
dti-1333	118	22	vascular	vascular	ADJ
dti-1333	118	23	disease	disease	NOUN
dti-1333	118	24	in	in	ADP
dti-1333	118	25	the	the	DET
dti-1333	118	26	french	french	ADJ
dti-1333	118	27	population	population	NOUN
dti-1333	118	28	,	,	PUNCT
dti-1333	118	29	despite	despite	SCONJ
dti-1333	118	30	a	a	DET
dti-1333	118	31	high	high	ADJ
dti-1333	118	32	level	level	NOUN
dti-1333	118	33	of	of	ADP
dti-1333	118	34	saturated	saturate	VERB
dti-1333	118	35	fats	fat	NOUN
dti-1333	118	36	in	in	ADP
dti-1333	118	37	their	their	PRON
dti-1333	118	38	diet	diet	NOUN
dti-1333	118	39	(	(	PUNCT
dti-1333	118	40	poussier	poussier	X
dti-1333	118	41	et	et	PROPN
dti-1333	118	42	al	al	PROPN
dti-1333	118	43	.	.	PROPN
dti-1333	118	44	2005	2005	NUM
dti-1333	118	45	;	;	PUNCT
dti-1333	118	46	zern	zern	NOUN
dti-1333	118	47	and	and	CCONJ
dti-1333	118	48	fernandez	fernandez	PROPN
dti-1333	118	49	,	,	PUNCT
dti-1333	118	50	2005	2005	NUM
dti-1333	118	51	;	;	PUNCT
dti-1333	118	52	renaud	renaud	NOUN
dti-1333	118	53	and	and	CCONJ
dti-1333	118	54	de	de	X
dti-1333	118	55	lorgeil	lorgeil	PROPN
dti-1333	118	56	,	,	PUNCT
dti-1333	118	57	1992	1992	NUM
dti-1333	118	58	;	;	PUNCT
dti-1333	118	59	burr	burr	NOUN
dti-1333	118	60	,	,	PUNCT
dti-1333	118	61	1995	1995	NUM
dti-1333	118	62	;	;	PUNCT
dti-1333	118	63	schäfer	schäfer	NOUN
dti-1333	118	64	et	et	PROPN
dti-1333	118	65	al	al	PROPN
dti-1333	118	66	.	.	PROPN
dti-1333	118	67	2007	2007	NUM
dti-1333	118	68	)	)	PUNCT
dti-1333	118	69	.	.	PUNCT
dti-1333	119	1	the	the	DET
dti-1333	119	2	polyphenol	polyphenol	NOUN
dti-1333	119	3	resveratrol	resveratrol	NOUN
dti-1333	119	4	(	(	PUNCT
dti-1333	119	5	trans-3,5,4'trihydroxystilbene	trans-3,5,4'trihydroxystilbene	ADJ
dti-1333	119	6	)	)	PUNCT
dti-1333	119	7	,	,	PUNCT
dti-1333	119	8	a	a	DET
dti-1333	119	9	stilbenoid	stilbenoid	ADJ
dti-1333	119	10	antioxidant	antioxidant	NOUN
dti-1333	119	11	found	find	VERB
dti-1333	119	12	in	in	ADP
dti-1333	119	13	the	the	DET
dti-1333	119	14	skin	skin	NOUN
dti-1333	119	15	of	of	ADP
dti-1333	119	16	red	red	ADJ
dti-1333	119	17	grapes	grape	NOUN
dti-1333	119	18	,	,	PUNCT
dti-1333	119	19	wine	wine	NOUN
dti-1333	119	20	,	,	PUNCT
dti-1333	119	21	peanuts	peanut	NOUN
dti-1333	119	22	,	,	PUNCT
dti-1333	119	23	and	and	CCONJ
dti-1333	119	24	some	some	DET
dti-1333	119	25	berries	berry	NOUN
dti-1333	119	26	,	,	PUNCT
dti-1333	119	27	has	have	AUX
dti-1333	119	28	been	be	AUX
dti-1333	119	29	shown	show	VERB
dti-1333	119	30	to	to	PART
dti-1333	119	31	exhibit	exhibit	VERB
dti-1333	119	32	alcoholindependent	alcoholindependent	VERB
dti-1333	119	33	cardioprotective	cardioprotective	ADJ
dti-1333	119	34	properties	property	NOUN
dti-1333	119	35	(	(	PUNCT
dti-1333	119	36	wang	wang	PROPN
dti-1333	119	37	et	et	PROPN
dti-1333	119	38	al	al	PROPN
dti-1333	119	39	.	.	PROPN
dti-1333	119	40	2005	2005	NUM
dti-1333	119	41	)	)	PUNCT
dti-1333	119	42	.	.	PUNCT
dti-1333	120	1	thus	thus	ADV
dti-1333	120	2	,	,	PUNCT
dti-1333	120	3	mild	mild	ADJ
dti-1333	120	4	-	-	PUNCT
dti-1333	120	5	to	to	ADP
dti-1333	120	6	-	-	PUNCT
dti-1333	120	7	moderate	moderate	ADJ
dti-1333	120	8	alcohol	alcohol	NOUN
dti-1333	120	9	consumption	consumption	NOUN
dti-1333	120	10	appears	appear	VERB
dti-1333	120	11	to	to	PART
dti-1333	120	12	be	be	AUX
dti-1333	120	13	reasonable	reasonable	ADJ
dti-1333	120	14	for	for	ADP
dti-1333	120	15	many	many	ADJ
dti-1333	120	16	people	people	NOUN
dti-1333	120	17	;	;	PUNCT
dti-1333	120	18	however	however	ADV
dti-1333	120	19	,	,	PUNCT
dti-1333	120	20	the	the	DET
dti-1333	120	21	potential	potential	ADJ
dti-1333	120	22	risks	risk	NOUN
dti-1333	120	23	associated	associate	VERB
dti-1333	120	24	with	with	ADP
dti-1333	120	25	hepatic	hepatic	ADJ
dti-1333	120	26	dysfunction	dysfunction	NOUN
dti-1333	120	27	and	and	CCONJ
dti-1333	120	28	addiction	addiction	NOUN
dti-1333	120	29	may	may	AUX
dti-1333	120	30	outweigh	outweigh	VERB
dti-1333	120	31	the	the	DET
dti-1333	120	32	benefi	benefi	PROPN
dti-1333	120	33	ts	ts	PROPN
dti-1333	120	34	.	.	PUNCT
dti-1333	120	35	improvement	improvement	NOUN
dti-1333	120	36	in	in	ADP
dti-1333	120	37	hdl	hdl	PROPN
dti-1333	120	38	-	-	PUNCT
dti-1333	120	39	c	c	PROPN
dti-1333	120	40	with	with	ADP
dti-1333	120	41	life	life	NOUN
dti-1333	120	42	style	style	NOUN
dti-1333	120	43	changes	change	NOUN
dti-1333	120	44	may	may	AUX
dti-1333	120	45	often	often	ADV
dti-1333	120	46	be	be	AUX
dti-1333	120	47	suffi	suffi	NOUN
dti-1333	120	48	cient	cient	NOUN
dti-1333	120	49	;	;	PUNCT
dti-1333	120	50	however	however	ADV
dti-1333	120	51	,	,	PUNCT
dti-1333	120	52	the	the	DET
dti-1333	120	53	interaction	interaction	NOUN
dti-1333	120	54	between	between	ADP
dti-1333	120	55	genes	gene	NOUN
dti-1333	120	56	and	and	CCONJ
dti-1333	120	57	the	the	DET
dti-1333	120	58	environment	environment	NOUN
dti-1333	120	59	may	may	AUX
dti-1333	120	60	infl	infl	PROPN
dti-1333	120	61	uence	uence	NOUN
dti-1333	120	62	the	the	DET
dti-1333	120	63	magnitude	magnitude	NOUN
dti-1333	120	64	of	of	ADP
dti-1333	120	65	any	any	DET
dti-1333	120	66	improvement	improvement	NOUN
dti-1333	120	67	.	.	PUNCT
dti-1333	121	1	thus	thus	ADV
dti-1333	121	2	,	,	PUNCT
dti-1333	121	3	when	when	SCONJ
dti-1333	121	4	life	life	NOUN
dti-1333	121	5	style	style	NOUN
dti-1333	121	6	modifi	modifi	NOUN
dti-1333	121	7	cations	cation	NOUN
dti-1333	121	8	are	be	AUX
dti-1333	121	9	insuffi	insuffi	ADJ
dti-1333	121	10	cient	cient	NOUN
dti-1333	121	11	,	,	PUNCT
dti-1333	121	12	medications	medication	NOUN
dti-1333	121	13	are	be	AUX
dti-1333	121	14	used	use	VERB
dti-1333	121	15	.	.	PUNCT
dti-1333	122	1	approaches	approach	NOUN
dti-1333	122	2	to	to	PART
dti-1333	122	3	raise	raise	VERB
dti-1333	122	4	anti	anti	ADJ
dti-1333	122	5	-	-	ADJ
dti-1333	122	6	atherogenic	atherogenic	ADJ
dti-1333	122	7	hdl	hdl	NOUN
dti-1333	122	8	-	-	PUNCT
dti-1333	122	9	c	c	PROPN
dti-1333	122	10	have	have	AUX
dti-1333	122	11	attracted	attract	VERB
dti-1333	122	12	much	much	ADJ
dti-1333	122	13	attention	attention	NOUN
dti-1333	122	14	,	,	PUNCT
dti-1333	122	15	because	because	SCONJ
dti-1333	122	16	of	of	ADP
dti-1333	122	17	expanding	expand	VERB
dti-1333	122	18	50	50	NUM
dti-1333	122	19	brown	brown	ADJ
dti-1333	122	20	and	and	CCONJ
dti-1333	122	21	chiacchia	chiacchia	NOUN
dti-1333	122	22	drug	drug	NOUN
dti-1333	122	23	target	target	NOUN
dti-1333	122	24	insights	insight	NOUN
dti-1333	122	25	2008:3	2008:3	NUM
dti-1333	122	26	disease	disease	NOUN
dti-1333	122	27	populations	population	NOUN
dti-1333	122	28	with	with	ADP
dti-1333	122	29	low	low	ADJ
dti-1333	122	30	levels	level	NOUN
dti-1333	122	31	of	of	ADP
dti-1333	122	32	hdl	hdl	PROPN
dti-1333	122	33	-	-	PUNCT
dti-1333	122	34	c	c	PROPN
dti-1333	122	35	or	or	CCONJ
dti-1333	122	36	high	high	ADJ
dti-1333	122	37	cholesterol	cholesterol	NOUN
dti-1333	122	38	,	,	PUNCT
dti-1333	122	39	such	such	ADJ
dti-1333	122	40	as	as	ADP
dti-1333	122	41	patients	patient	NOUN
dti-1333	122	42	with	with	ADP
dti-1333	122	43	type	type	NOUN
dti-1333	122	44	2	2	NUM
dti-1333	122	45	diabetes	diabetes	NOUN
dti-1333	122	46	,	,	PUNCT
dti-1333	122	47	metabolic	metabolic	NOUN
dti-1333	122	48	syndrome	syndrome	NOUN
dti-1333	122	49	,	,	PUNCT
dti-1333	122	50	dyslipidemia	dyslipidemia	NOUN
dti-1333	122	51	,	,	PUNCT
dti-1333	122	52	and	and	CCONJ
dti-1333	122	53	menopause	menopause	NOUN
dti-1333	122	54	.	.	PUNCT
dti-1333	123	1	to	to	ADP
dti-1333	123	2	date	date	NOUN
dti-1333	123	3	,	,	PUNCT
dti-1333	123	4	several	several	ADJ
dti-1333	123	5	medications	medication	NOUN
dti-1333	123	6	that	that	PRON
dti-1333	123	7	have	have	AUX
dti-1333	123	8	been	be	AUX
dti-1333	123	9	approved	approve	VERB
dti-1333	123	10	that	that	PRON
dti-1333	123	11	increase	increase	NOUN
dti-1333	123	12	hdl	hdl	PROPN
dti-1333	123	13	-	-	PUNCT
dti-1333	123	14	c	c	PROPN
dti-1333	123	15	and	and	CCONJ
dti-1333	123	16	new	new	ADJ
dti-1333	123	17	approaches	approach	NOUN
dti-1333	123	18	are	be	AUX
dti-1333	123	19	being	be	AUX
dti-1333	123	20	sought	seek	VERB
dti-1333	123	21	.	.	PUNCT
dti-1333	124	1	niacin	niacin	PROPN
dti-1333	124	2	niacin	niacin	PROPN
dti-1333	124	3	is	be	AUX
dti-1333	124	4	the	the	DET
dti-1333	124	5	most	most	ADV
dti-1333	124	6	effective	effective	ADJ
dti-1333	124	7	drug	drug	NOUN
dti-1333	124	8	currently	currently	ADV
dti-1333	124	9	available	available	ADJ
dti-1333	124	10	to	to	PART
dti-1333	124	11	raise	raise	VERB
dti-1333	124	12	hdl	hdl	PROPN
dti-1333	124	13	-	-	PUNCT
dti-1333	124	14	c	c	NOUN
dti-1333	124	15	levels	level	NOUN
dti-1333	124	16	.	.	PUNCT
dti-1333	125	1	at	at	ADP
dti-1333	125	2	higher	high	ADJ
dti-1333	125	3	pharmacological	pharmacological	ADJ
dti-1333	125	4	doses	dose	NOUN
dti-1333	125	5	,	,	PUNCT
dti-1333	125	6	niacin	niacin	NOUN
dti-1333	125	7	can	can	AUX
dti-1333	125	8	reduce	reduce	VERB
dti-1333	125	9	ldl	ldl	NOUN
dti-1333	125	10	-	-	PUNCT
dti-1333	125	11	c	c	NOUN
dti-1333	125	12	,	,	PUNCT
dti-1333	125	13	triglycerides	triglyceride	NOUN
dti-1333	125	14	,	,	PUNCT
dti-1333	125	15	and	and	CCONJ
dti-1333	125	16	apob	apob	ADV
dti-1333	125	17	,	,	PUNCT
dti-1333	125	18	while	while	SCONJ
dti-1333	125	19	increasing	increase	VERB
dti-1333	125	20	hdl	hdl	PROPN
dti-1333	125	21	-	-	PUNCT
dti-1333	125	22	c	c	PROPN
dti-1333	125	23	and	and	CCONJ
dti-1333	125	24	apoa	apoa	PROPN
dti-1333	125	25	-	-	PUNCT
dti-1333	125	26	i	i	PROPN
dti-1333	125	27	(	(	PUNCT
dti-1333	125	28	chapman	chapman	PROPN
dti-1333	125	29	,	,	PUNCT
dti-1333	125	30	2005	2005	NUM
dti-1333	125	31	)	)	PUNCT
dti-1333	125	32	.	.	PUNCT
dti-1333	126	1	these	these	DET
dti-1333	126	2	benefi	benefi	PROPN
dti-1333	126	3	cial	cial	ADJ
dti-1333	126	4	lipoprotein	lipoprotein	ADJ
dti-1333	126	5	changes	change	NOUN
dti-1333	126	6	have	have	AUX
dti-1333	126	7	been	be	AUX
dti-1333	126	8	shown	show	VERB
dti-1333	126	9	to	to	PART
dti-1333	126	10	translate	translate	VERB
dti-1333	126	11	into	into	ADP
dti-1333	126	12	clinical	clinical	ADJ
dti-1333	126	13	benefi	benefi	PROPN
dti-1333	126	14	ts	ts	PROPN
dti-1333	126	15	,	,	PUNCT
dti-1333	126	16	decreasing	decrease	VERB
dti-1333	126	17	morbidity	morbidity	NOUN
dti-1333	126	18	and	and	CCONJ
dti-1333	126	19	mortality	mortality	NOUN
dti-1333	126	20	from	from	ADP
dti-1333	126	21	cardiovascular	cardiovascular	ADJ
dti-1333	126	22	causes	cause	NOUN
dti-1333	126	23	(	(	PUNCT
dti-1333	126	24	mccormack	mccormack	PROPN
dti-1333	126	25	and	and	CCONJ
dti-1333	126	26	keating	keating	PROPN
dti-1333	126	27	,	,	PUNCT
dti-1333	126	28	2005	2005	NUM
dti-1333	126	29	)	)	PUNCT
dti-1333	126	30	.	.	PUNCT
dti-1333	127	1	nicotinic	nicotinic	ADJ
dti-1333	127	2	acid	acid	NOUN
dti-1333	127	3	,	,	PUNCT
dti-1333	127	4	as	as	ADP
dti-1333	127	5	vitamin	vitamin	NOUN
dti-1333	127	6	b3	b3	NOUN
dti-1333	127	7	,	,	PUNCT
dti-1333	127	8	is	be	AUX
dti-1333	127	9	available	available	ADJ
dti-1333	127	10	without	without	ADP
dti-1333	127	11	prescription	prescription	NOUN
dti-1333	127	12	;	;	PUNCT
dti-1333	127	13	however	however	ADV
dti-1333	127	14	,	,	PUNCT
dti-1333	127	15	side	side	ADJ
dti-1333	127	16	effects	effect	NOUN
dti-1333	127	17	tend	tend	VERB
dti-1333	127	18	to	to	PART
dti-1333	127	19	be	be	AUX
dti-1333	127	20	frequent	frequent	ADJ
dti-1333	127	21	when	when	SCONJ
dti-1333	127	22	taken	take	VERB
dti-1333	127	23	under	under	ADP
dti-1333	127	24	suboptimal	suboptimal	ADJ
dti-1333	127	25	conditions	condition	NOUN
dti-1333	127	26	.	.	PUNCT
dti-1333	128	1	extendedor	extendedor	PROPN
dti-1333	128	2	prolonged	prolong	VERB
dti-1333	128	3	-	-	PUNCT
dti-1333	128	4	release	release	NOUN
dti-1333	128	5	niacin	niacin	NOUN
dti-1333	128	6	(	(	PUNCT
dti-1333	128	7	niaspan	niaspan	PROPN
dti-1333	128	8	)	)	PUNCT
dti-1333	128	9	,	,	PUNCT
dti-1333	128	10	marketed	market	VERB
dti-1333	128	11	by	by	ADP
dti-1333	128	12	kos	kos	PROPN
dti-1333	128	13	pharmaceuticals	pharmaceutical	NOUN
dti-1333	128	14	,	,	PUNCT
dti-1333	128	15	decreases	decrease	VERB
dti-1333	128	16	fl	fl	PRON
dti-1333	128	17	ushing	ushing	NOUN
dti-1333	128	18	,	,	PUNCT
dti-1333	128	19	niacin	niacin	PROPN
dti-1333	128	20	’s	’s	PART
dti-1333	128	21	most	most	ADV
dti-1333	128	22	common	common	ADJ
dti-1333	128	23	side	side	NOUN
dti-1333	128	24	effect	effect	NOUN
dti-1333	128	25	and	and	CCONJ
dti-1333	128	26	increased	increase	VERB
dti-1333	128	27	hdl	hdl	PROPN
dti-1333	128	28	-	-	PUNCT
dti-1333	128	29	c	c	PROPN
dti-1333	128	30	by	by	ADP
dti-1333	128	31	~25	~25	NUM
dti-1333	128	32	%	%	NOUN
dti-1333	128	33	from	from	ADP
dti-1333	128	34	baseline	baseline	NOUN
dti-1333	128	35	at	at	ADP
dti-1333	128	36	200	200	NUM
dti-1333	128	37	mg	mg	NOUN
dti-1333	128	38	/	/	SYM
dti-1333	128	39	kg	kg	PROPN
dti-1333	128	40	in	in	ADP
dti-1333	128	41	clinical	clinical	ADJ
dti-1333	128	42	studies	study	NOUN
dti-1333	128	43	(	(	PUNCT
dti-1333	128	44	pal	pal	NOUN
dti-1333	128	45	and	and	CCONJ
dti-1333	128	46	pillarisetti	pillarisetti	NOUN
dti-1333	128	47	,	,	PUNCT
dti-1333	128	48	2007	2007	NUM
dti-1333	128	49	;	;	PUNCT
dti-1333	128	50	mccormack	mccormack	PROPN
dti-1333	128	51	and	and	CCONJ
dti-1333	128	52	keating	keating	PROPN
dti-1333	128	53	,	,	PUNCT
dti-1333	128	54	2005	2005	NUM
dti-1333	128	55	;	;	PUNCT
dti-1333	128	56	birjmohun	birjmohun	PROPN
dti-1333	128	57	et	et	PROPN
dti-1333	128	58	al	al	PROPN
dti-1333	128	59	.	.	PROPN
dti-1333	128	60	2004	2004	NUM
dti-1333	128	61	)	)	PUNCT
dti-1333	128	62	.	.	PUNCT
dti-1333	129	1	with	with	ADP
dti-1333	129	2	the	the	DET
dti-1333	129	3	discovery	discovery	NOUN
dti-1333	129	4	of	of	ADP
dti-1333	129	5	the	the	DET
dti-1333	129	6	niacin	niacin	NOUN
dti-1333	129	7	receptor	receptor	NOUN
dti-1333	129	8	(	(	PUNCT
dti-1333	129	9	hm74a	hm74a	INTJ
dti-1333	129	10	,	,	PUNCT
dti-1333	129	11	puma	puma	PROPN
dti-1333	129	12	-	-	PUNCT
dti-1333	129	13	g	g	NOUN
dti-1333	129	14	)	)	PUNCT
dti-1333	129	15	,	,	PUNCT
dti-1333	129	16	several	several	ADJ
dti-1333	129	17	drug	drug	NOUN
dti-1333	129	18	companies	company	NOUN
dti-1333	129	19	are	be	AUX
dti-1333	129	20	working	work	VERB
dti-1333	129	21	on	on	ADP
dti-1333	129	22	developing	develop	VERB
dti-1333	129	23	novel	novel	ADJ
dti-1333	129	24	agonists	agonist	NOUN
dti-1333	129	25	(	(	PUNCT
dti-1333	129	26	pal	pal	NOUN
dti-1333	129	27	and	and	CCONJ
dti-1333	129	28	pillarisetti	pillarisetti	NOUN
dti-1333	129	29	,	,	PUNCT
dti-1333	129	30	2007	2007	NUM
dti-1333	129	31	)	)	PUNCT
dti-1333	129	32	.	.	PUNCT
dti-1333	130	1	fibrates	fibrate	NOUN
dti-1333	130	2	and	and	CCONJ
dti-1333	130	3	ppar	ppar	NOUN
dti-1333	130	4	agonists	agonist	VERB
dti-1333	130	5	the	the	DET
dti-1333	130	6	peroxisome	peroxisome	PROPN
dti-1333	130	7	proliferator	proliferator	NOUN
dti-1333	130	8	activated	activate	VERB
dti-1333	130	9	receptor	receptor	NOUN
dti-1333	130	10	(	(	PUNCT
dti-1333	130	11	ppar	ppar	NOUN
dti-1333	130	12	)	)	PUNCT
dti-1333	130	13	nuclear	nuclear	ADJ
dti-1333	130	14	receptors	receptor	NOUN
dti-1333	130	15	are	be	AUX
dti-1333	130	16	believed	believe	VERB
dti-1333	130	17	to	to	PART
dti-1333	130	18	mediate	mediate	VERB
dti-1333	130	19	the	the	DET
dti-1333	130	20	activity	activity	NOUN
dti-1333	130	21	of	of	ADP
dti-1333	130	22	the	the	DET
dti-1333	130	23	fi	fi	NOUN
dti-1333	130	24	brates	brate	NOUN
dti-1333	130	25	(	(	PUNCT
dti-1333	130	26	fenofi	fenofi	PROPN
dti-1333	130	27	brate	brate	PROPN
dti-1333	130	28	activates	activate	VERB
dti-1333	130	29	pparα	pparα	NOUN
dti-1333	130	30	)	)	PUNCT
dti-1333	130	31	(	(	PUNCT
dti-1333	130	32	pal	pal	NOUN
dti-1333	130	33	and	and	CCONJ
dti-1333	130	34	pillarisetti	pillarisetti	NOUN
dti-1333	130	35	,	,	PUNCT
dti-1333	130	36	2007	2007	NUM
dti-1333	130	37	;	;	PUNCT
dti-1333	130	38	fruchart	fruchart	NOUN
dti-1333	130	39	and	and	CCONJ
dti-1333	130	40	duriez	duriez	NOUN
dti-1333	130	41	,	,	PUNCT
dti-1333	130	42	2006	2006	NUM
dti-1333	130	43	)	)	PUNCT
dti-1333	130	44	.	.	PUNCT
dti-1333	131	1	the	the	DET
dti-1333	131	2	fi	fi	NOUN
dti-1333	131	3	brate	brate	PROPN
dti-1333	131	4	class	class	NOUN
dti-1333	131	5	of	of	ADP
dti-1333	131	6	drugs	drug	NOUN
dti-1333	131	7	has	have	AUX
dti-1333	131	8	been	be	AUX
dti-1333	131	9	broadly	broadly	ADV
dti-1333	131	10	used	use	VERB
dti-1333	131	11	in	in	ADP
dti-1333	131	12	the	the	DET
dti-1333	131	13	clinical	clinical	ADJ
dti-1333	131	14	treatment	treatment	NOUN
dti-1333	131	15	of	of	ADP
dti-1333	131	16	dyslipidemia	dyslipidemia	NOUN
dti-1333	131	17	(	(	PUNCT
dti-1333	131	18	pal	pal	NOUN
dti-1333	131	19	and	and	CCONJ
dti-1333	131	20	pillarisetti	pillarisetti	NOUN
dti-1333	131	21	,	,	PUNCT
dti-1333	131	22	2007	2007	NUM
dti-1333	131	23	)	)	PUNCT
dti-1333	131	24	.	.	PUNCT
dti-1333	132	1	the	the	DET
dti-1333	132	2	fibrates	fibrate	NOUN
dti-1333	132	3	typically	typically	ADV
dti-1333	132	4	raise	raise	VERB
dti-1333	132	5	hdl	hdl	PROPN
dti-1333	132	6	levels	level	NOUN
dti-1333	132	7	by	by	ADP
dti-1333	132	8	10%–15	10%–15	NUM
dti-1333	132	9	%	%	NOUN
dti-1333	132	10	and	and	CCONJ
dti-1333	132	11	can	can	AUX
dti-1333	132	12	also	also	ADV
dti-1333	132	13	lower	lower	VERB
dti-1333	132	14	triglyceride	triglyceride	ADP
dti-1333	132	15	levels	level	NOUN
dti-1333	132	16	by	by	ADP
dti-1333	132	17	up	up	ADP
dti-1333	132	18	to	to	PART
dti-1333	132	19	60	60	NUM
dti-1333	132	20	%	%	NOUN
dti-1333	132	21	,	,	PUNCT
dti-1333	132	22	though	though	SCONJ
dti-1333	132	23	they	they	PRON
dti-1333	132	24	have	have	VERB
dti-1333	132	25	little	little	ADJ
dti-1333	132	26	effect	effect	NOUN
dti-1333	132	27	on	on	ADP
dti-1333	132	28	ldl	ldl	NOUN
dti-1333	132	29	levels	level	NOUN
dti-1333	132	30	.	.	PUNCT
dti-1333	133	1	in	in	ADP
dti-1333	133	2	subjects	subject	NOUN
dti-1333	133	3	with	with	ADP
dti-1333	133	4	low	low	ADJ
dti-1333	133	5	hdl	hdl	PROPN
dti-1333	133	6	-	-	PUNCT
dti-1333	133	7	c	c	PROPN
dti-1333	133	8	,	,	PUNCT
dti-1333	133	9	gemfibrozil	gemfibrozil	PROPN
dti-1333	133	10	administration	administration	NOUN
dti-1333	133	11	resulted	result	VERB
dti-1333	133	12	in	in	ADP
dti-1333	133	13	a	a	DET
dti-1333	133	14	6	6	NUM
dti-1333	133	15	%	%	NOUN
dti-1333	133	16	increase	increase	NOUN
dti-1333	133	17	in	in	ADP
dti-1333	133	18	hdl	hdl	PROPN
dti-1333	133	19	-	-	PUNCT
dti-1333	133	20	c	c	NOUN
dti-1333	133	21	levels	level	NOUN
dti-1333	133	22	and	and	CCONJ
dti-1333	133	23	a	a	DET
dti-1333	133	24	22	22	NUM
dti-1333	133	25	%	%	NOUN
dti-1333	133	26	decrease	decrease	NOUN
dti-1333	133	27	in	in	ADP
dti-1333	133	28	chd	chd	NOUN
dti-1333	133	29	risk	risk	NOUN
dti-1333	133	30	(	(	PUNCT
dti-1333	133	31	rubins	rubin	NOUN
dti-1333	133	32	et	et	NOUN
dti-1333	133	33	al	al	PROPN
dti-1333	133	34	.	.	PROPN
dti-1333	133	35	1999	1999	NUM
dti-1333	133	36	)	)	PUNCT
dti-1333	133	37	.	.	PUNCT
dti-1333	134	1	the	the	DET
dti-1333	134	2	observed	observe	VERB
dti-1333	134	3	hdl	hdl	PROPN
dti-1333	134	4	-	-	PUNCT
dti-1333	134	5	c	c	PROPN
dti-1333	134	6	elevation	elevation	NOUN
dti-1333	134	7	is	be	AUX
dti-1333	134	8	the	the	DET
dti-1333	134	9	result	result	NOUN
dti-1333	134	10	of	of	ADP
dti-1333	134	11	transcriptional	transcriptional	ADJ
dti-1333	134	12	induction	induction	NOUN
dti-1333	134	13	of	of	ADP
dti-1333	134	14	apoa	apoa	PROPN
dti-1333	134	15	-	-	PUNCT
dti-1333	134	16	i	i	NOUN
dti-1333	134	17	gene	gene	NOUN
dti-1333	134	18	expression	expression	NOUN
dti-1333	134	19	,	,	PUNCT
dti-1333	134	20	mediated	mediate	VERB
dti-1333	134	21	by	by	ADP
dti-1333	134	22	the	the	DET
dti-1333	134	23	interaction	interaction	NOUN
dti-1333	134	24	of	of	ADP
dti-1333	134	25	pparα	pparα	NOUN
dti-1333	134	26	with	with	ADP
dti-1333	134	27	a	a	DET
dti-1333	134	28	functional	functional	ADJ
dti-1333	134	29	ppre	ppre	NOUN
dti-1333	134	30	,	,	PUNCT
dti-1333	134	31	localized	localize	VERB
dti-1333	134	32	in	in	ADP
dti-1333	134	33	the	the	DET
dti-1333	134	34	a	a	DET
dti-1333	134	35	site	site	NOUN
dti-1333	134	36	of	of	ADP
dti-1333	134	37	the	the	DET
dti-1333	134	38	apoa	apoa	NOUN
dti-1333	134	39	-	-	PUNCT
dti-1333	134	40	i	i	PROPN
dti-1333	134	41	promoter	promoter	NOUN
dti-1333	134	42	(	(	PUNCT
dti-1333	134	43	vu	vu	NOUN
dti-1333	134	44	-	-	NOUN
dti-1333	134	45	dac	dac	NOUN
dti-1333	134	46	et	et	PROPN
dti-1333	134	47	al	al	PROPN
dti-1333	134	48	.	.	PROPN
dti-1333	134	49	1994	1994	NUM
dti-1333	134	50	)	)	PUNCT
dti-1333	134	51	.	.	PUNCT
dti-1333	135	1	pparα	pparα	PROPN
dti-1333	135	2	regulates	regulate	VERB
dti-1333	135	3	other	other	ADJ
dti-1333	135	4	genes	gene	NOUN
dti-1333	135	5	involved	involve	VERB
dti-1333	135	6	in	in	ADP
dti-1333	135	7	lipid	lipid	ADJ
dti-1333	135	8	metabolism	metabolism	NOUN
dti-1333	135	9	,	,	PUNCT
dti-1333	135	10	hemostasis	hemostasis	NOUN
dti-1333	135	11	,	,	PUNCT
dti-1333	135	12	and	and	CCONJ
dti-1333	135	13	infl	infl	PROPN
dti-1333	135	14	ammation	ammation	PROPN
dti-1333	135	15	,	,	PUNCT
dti-1333	135	16	in	in	ADP
dti-1333	135	17	response	response	NOUN
dti-1333	135	18	to	to	AUX
dti-1333	135	19	fatty	fatty	VERB
dti-1333	135	20	acids	acid	NOUN
dti-1333	135	21	and	and	CCONJ
dti-1333	135	22	fi	fi	NOUN
dti-1333	135	23	brates	brate	NOUN
dti-1333	135	24	,	,	PUNCT
dti-1333	135	25	making	make	VERB
dti-1333	135	26	it	it	PRON
dti-1333	135	27	a	a	DET
dti-1333	135	28	candidate	candidate	NOUN
dti-1333	135	29	gene	gene	NOUN
dti-1333	135	30	for	for	ADP
dti-1333	135	31	risk	risk	NOUN
dti-1333	135	32	of	of	ADP
dti-1333	135	33	dyslipidemia	dyslipidemia	NOUN
dti-1333	135	34	,	,	PUNCT
dti-1333	135	35	atherosclerosis	atherosclerosis	NOUN
dti-1333	135	36	,	,	PUNCT
dti-1333	135	37	and	and	CCONJ
dti-1333	135	38	coronary	coronary	ADJ
dti-1333	135	39	artery	artery	NOUN
dti-1333	135	40	disease	disease	NOUN
dti-1333	135	41	(	(	PUNCT
dti-1333	135	42	pal	pal	NOUN
dti-1333	135	43	and	and	CCONJ
dti-1333	135	44	pillarisetti	pillarisetti	NOUN
dti-1333	135	45	,	,	PUNCT
dti-1333	135	46	2007	2007	NUM
dti-1333	135	47	)	)	PUNCT
dti-1333	135	48	.	.	PUNCT
dti-1333	136	1	unfortunately	unfortunately	ADV
dti-1333	136	2	,	,	PUNCT
dti-1333	136	3	the	the	DET
dti-1333	136	4	development	development	NOUN
dti-1333	136	5	of	of	ADP
dti-1333	136	6	effective	effective	ADJ
dti-1333	136	7	medications	medication	NOUN
dti-1333	136	8	in	in	ADP
dti-1333	136	9	this	this	DET
dti-1333	136	10	drug	drug	NOUN
dti-1333	136	11	class	class	NOUN
dti-1333	136	12	has	have	AUX
dti-1333	136	13	been	be	AUX
dti-1333	136	14	hampered	hamper	VERB
dti-1333	136	15	by	by	ADP
dti-1333	136	16	safety	safety	NOUN
dti-1333	136	17	concerns	concern	NOUN
dti-1333	136	18	and	and	CCONJ
dti-1333	136	19	increased	increase	VERB
dti-1333	136	20	atherogenic	atherogenic	ADJ
dti-1333	136	21	lipids	lipid	NOUN
dti-1333	136	22	(	(	PUNCT
dti-1333	136	23	nissen	nissen	PROPN
dti-1333	136	24	et	et	PROPN
dti-1333	136	25	al	al	PROPN
dti-1333	136	26	.	.	PROPN
dti-1333	136	27	2007a	2007a	NUM
dti-1333	136	28	)	)	PUNCT
dti-1333	136	29	.	.	PUNCT
dti-1333	137	1	for	for	ADP
dti-1333	137	2	example	example	NOUN
dti-1333	137	3	,	,	PUNCT
dti-1333	137	4	phase	phase	NOUN
dti-1333	137	5	ii	ii	PROPN
dti-1333	137	6	results	result	NOUN
dti-1333	137	7	on	on	ADP
dti-1333	137	8	eli	eli	PROPN
dti-1333	137	9	lilly	lilly	PROPN
dti-1333	137	10	’s	’s	PART
dti-1333	137	11	pparα	pparα	NOUN
dti-1333	137	12	agonist	agonist	NOUN
dti-1333	137	13	,	,	PUNCT
dti-1333	137	14	ly518674	ly518674	PROPN
dti-1333	137	15	demonstrated	demonstrate	VERB
dti-1333	137	16	a	a	DET
dti-1333	137	17	dose	dose	NOUN
dti-1333	137	18	-	-	PUNCT
dti-1333	137	19	related	relate	VERB
dti-1333	137	20	increase	increase	NOUN
dti-1333	137	21	in	in	ADP
dti-1333	137	22	ldl	ldl	NOUN
dti-1333	137	23	-	-	PUNCT
dti-1333	137	24	c	c	PROPN
dti-1333	137	25	that	that	PRON
dti-1333	137	26	appeared	appear	VERB
dti-1333	137	27	to	to	PART
dti-1333	137	28	correlate	correlate	VERB
dti-1333	137	29	with	with	ADP
dti-1333	137	30	baseline	baseline	ADJ
dti-1333	137	31	triglycerides	triglyceride	NOUN
dti-1333	137	32	(	(	PUNCT
dti-1333	137	33	nissen	nissen	PROPN
dti-1333	137	34	et	et	PROPN
dti-1333	137	35	al	al	PROPN
dti-1333	137	36	.	.	PROPN
dti-1333	137	37	2007a	2007a	NUM
dti-1333	137	38	)	)	PUNCT
dti-1333	137	39	.	.	PUNCT
dti-1333	138	1	statins	statins	PROPN
dti-1333	138	2	statins	statins	PROPN
dti-1333	138	3	are	be	AUX
dti-1333	138	4	the	the	DET
dti-1333	138	5	most	most	ADV
dti-1333	138	6	effective	effective	ADJ
dti-1333	138	7	pharmacological	pharmacological	ADJ
dti-1333	138	8	means	mean	NOUN
dti-1333	138	9	of	of	ADP
dti-1333	138	10	lowering	lower	VERB
dti-1333	138	11	ldl	ldl	NOUN
dti-1333	138	12	-	-	PUNCT
dti-1333	138	13	c.	c.	NOUN
dti-1333	138	14	they	they	PRON
dti-1333	138	15	inhibit	inhibit	VERB
dti-1333	138	16	3	3	NUM
dti-1333	138	17	-	-	PUNCT
dti-1333	138	18	hydroxy3	hydroxy3	NOUN
dti-1333	138	19	-	-	PUNCT
dti-1333	138	20	methylglutaryl	methylglutaryl	NOUN
dti-1333	138	21	coenzyme	coenzyme	PROPN
dti-1333	138	22	a	a	PRON
dti-1333	138	23	(	(	PUNCT
dti-1333	138	24	hmg	hmg	NOUN
dti-1333	138	25	-	-	PUNCT
dti-1333	138	26	coa	coa	NOUN
dti-1333	138	27	)	)	PUNCT
dti-1333	138	28	reductase	reductase	NOUN
dti-1333	138	29	,	,	PUNCT
dti-1333	138	30	the	the	DET
dti-1333	138	31	enzyme	enzyme	NOUN
dti-1333	138	32	that	that	PRON
dti-1333	138	33	catalyzes	catalyze	VERB
dti-1333	138	34	the	the	DET
dti-1333	138	35	ratelimiting	ratelimite	VERB
dti-1333	138	36	step	step	NOUN
dti-1333	138	37	in	in	ADP
dti-1333	138	38	cholesterol	cholesterol	NOUN
dti-1333	138	39	synthesis	synthesis	NOUN
dti-1333	138	40	(	(	PUNCT
dti-1333	138	41	slater	slater	NOUN
dti-1333	138	42	and	and	CCONJ
dti-1333	138	43	macdonald	macdonald	PROPN
dti-1333	138	44	,	,	PUNCT
dti-1333	138	45	1988	1988	NUM
dti-1333	138	46	)	)	PUNCT
dti-1333	138	47	.	.	PUNCT
dti-1333	139	1	by	by	ADP
dti-1333	139	2	inhibiting	inhibit	VERB
dti-1333	139	3	cholesterol	cholesterol	NOUN
dti-1333	139	4	synthesis	synthesis	NOUN
dti-1333	139	5	in	in	ADP
dti-1333	139	6	the	the	DET
dti-1333	139	7	liver	liver	NOUN
dti-1333	139	8	,	,	PUNCT
dti-1333	139	9	statins	statin	NOUN
dti-1333	139	10	activate	activate	VERB
dti-1333	139	11	hepatocyte	hepatocyte	NOUN
dti-1333	139	12	ldl	ldl	NOUN
dti-1333	139	13	receptors	receptor	NOUN
dti-1333	139	14	and	and	CCONJ
dti-1333	139	15	produce	produce	VERB
dti-1333	139	16	signifi	signifi	NOUN
dti-1333	139	17	ca	can	AUX
dti-1333	139	18	nt	not	PART
dti-1333	139	19	reductions	reduction	NOUN
dti-1333	139	20	in	in	ADP
dti-1333	139	21	circulating	circulate	VERB
dti-1333	139	22	ldl	ldl	NOUN
dti-1333	139	23	-	-	PUNCT
dti-1333	139	24	c	c	PROPN
dti-1333	139	25	(	(	PUNCT
dti-1333	139	26	slater	slater	NOUN
dti-1333	139	27	and	and	CCONJ
dti-1333	139	28	macdonald	macdonald	PROPN
dti-1333	139	29	,	,	PUNCT
dti-1333	139	30	1988	1988	NUM
dti-1333	139	31	)	)	PUNCT
dti-1333	139	32	.	.	PUNCT
dti-1333	140	1	statins	statin	NOUN
dti-1333	140	2	have	have	AUX
dti-1333	140	3	been	be	AUX
dti-1333	140	4	shown	show	VERB
dti-1333	140	5	in	in	ADP
dti-1333	140	6	many	many	ADJ
dti-1333	140	7	large	large	ADJ
dti-1333	140	8	,	,	PUNCT
dti-1333	140	9	randomized	randomize	VERB
dti-1333	140	10	clinical	clinical	ADJ
dti-1333	140	11	trials	trial	NOUN
dti-1333	140	12	to	to	PART
dti-1333	140	13	reduce	reduce	VERB
dti-1333	140	14	ldl	ldl	NOUN
dti-1333	140	15	-	-	PUNCT
dti-1333	140	16	c	c	NOUN
dti-1333	140	17	,	,	PUNCT
dti-1333	140	18	thereby	thereby	ADV
dti-1333	140	19	reducing	reduce	VERB
dti-1333	140	20	the	the	DET
dti-1333	140	21	risk	risk	NOUN
dti-1333	140	22	of	of	ADP
dti-1333	140	23	cardiovascular	cardiovascular	ADJ
dti-1333	140	24	events	event	NOUN
dti-1333	140	25	and	and	CCONJ
dti-1333	140	26	decreasing	decrease	VERB
dti-1333	140	27	mortality	mortality	NOUN
dti-1333	140	28	(	(	PUNCT
dti-1333	140	29	nicholls	nicholl	NOUN
dti-1333	140	30	et	et	PROPN
dti-1333	140	31	al	al	PROPN
dti-1333	140	32	.	.	PROPN
dti-1333	140	33	2007	2007	NUM
dti-1333	140	34	)	)	PUNCT
dti-1333	140	35	.	.	PUNCT
dti-1333	141	1	statins	statin	NOUN
dti-1333	141	2	also	also	ADV
dti-1333	141	3	increase	increase	VERB
dti-1333	141	4	levels	level	NOUN
dti-1333	141	5	of	of	ADP
dti-1333	141	6	hdl	hdl	PROPN
dti-1333	141	7	-	-	PUNCT
dti-1333	141	8	c	c	PROPN
dti-1333	141	9	and	and	CCONJ
dti-1333	141	10	apoa	apoa	PROPN
dti-1333	141	11	-	-	PUNCT
dti-1333	141	12	i.	i.	PROPN
dti-1333	141	13	in	in	ADP
dti-1333	141	14	human	human	ADJ
dti-1333	141	15	hepg2	hepg2	NOUN
dti-1333	141	16	cells	cell	NOUN
dti-1333	141	17	and	and	CCONJ
dti-1333	141	18	hamster	hamster	PROPN
dti-1333	141	19	primary	primary	ADJ
dti-1333	141	20	hepatocytes	hepatocyte	NOUN
dti-1333	141	21	,	,	PUNCT
dti-1333	141	22	statin	statin	ADJ
dti-1333	141	23	treatment	treatment	NOUN
dti-1333	141	24	increased	increase	VERB
dti-1333	141	25	apoa	apoa	NOUN
dti-1333	141	26	-	-	PUNCT
dti-1333	141	27	i	i	PROPN
dti-1333	141	28	levels	level	NOUN
dti-1333	141	29	(	(	PUNCT
dti-1333	141	30	bonn	bonn	PROPN
dti-1333	141	31	et	et	PROPN
dti-1333	141	32	al	al	PROPN
dti-1333	141	33	.	.	PROPN
dti-1333	141	34	2002	2002	NUM
dti-1333	141	35	)	)	PUNCT
dti-1333	141	36	.	.	PUNCT
dti-1333	142	1	furthermore	furthermore	ADV
dti-1333	142	2	,	,	PUNCT
dti-1333	142	3	the	the	DET
dti-1333	142	4	statin	statin	ADJ
dti-1333	142	5	response	response	NOUN
dti-1333	142	6	element	element	NOUN
dti-1333	142	7	has	have	AUX
dti-1333	142	8	been	be	AUX
dti-1333	142	9	shown	show	VERB
dti-1333	142	10	to	to	PART
dti-1333	142	11	coincide	coincide	VERB
dti-1333	142	12	with	with	ADP
dti-1333	142	13	the	the	DET
dti-1333	142	14	pparα	pparα	NOUN
dti-1333	142	15	response	response	NOUN
dti-1333	142	16	element	element	NOUN
dti-1333	142	17	,	,	PUNCT
dti-1333	142	18	known	know	VERB
dti-1333	142	19	to	to	PART
dti-1333	142	20	confer	confer	VERB
dti-1333	142	21	fi	fi	NOUN
dti-1333	142	22	brate	brate	PROPN
dti-1333	142	23	responsiveness	responsiveness	NOUN
dti-1333	142	24	in	in	ADP
dti-1333	142	25	the	the	DET
dti-1333	142	26	apoa	apoa	NOUN
dti-1333	142	27	-	-	PUNCT
dti-1333	142	28	i	i	PRON
dti-1333	142	29	gene	gene	NOUN
dti-1333	142	30	(	(	PUNCT
dti-1333	142	31	maejima	maejima	PROPN
dti-1333	142	32	et	et	PROPN
dti-1333	142	33	al	al	PROPN
dti-1333	142	34	.	.	PROPN
dti-1333	142	35	2004	2004	NUM
dti-1333	142	36	)	)	PUNCT
dti-1333	142	37	.	.	PUNCT
dti-1333	143	1	statin	statin	PROPN
dti-1333	143	2	therapy	therapy	NOUN
dti-1333	143	3	is	be	AUX
dti-1333	143	4	associated	associate	VERB
dti-1333	143	5	with	with	ADP
dti-1333	143	6	regression	regression	NOUN
dti-1333	143	7	of	of	ADP
dti-1333	143	8	coronary	coronary	ADJ
dti-1333	143	9	atherosclerosis	atherosclerosis	NOUN
dti-1333	143	10	,	,	PUNCT
dti-1333	143	11	when	when	SCONJ
dti-1333	143	12	ldl	ldl	NOUN
dti-1333	143	13	-	-	PUNCT
dti-1333	143	14	c	c	PROPN
dti-1333	143	15	is	be	AUX
dti-1333	143	16	substantially	substantially	ADV
dti-1333	143	17	reduced	reduce	VERB
dti-1333	143	18	and	and	CCONJ
dti-1333	143	19	hdl	hdl	PROPN
dti-1333	143	20	-	-	PUNCT
dti-1333	143	21	c	c	PROPN
dti-1333	143	22	is	be	AUX
dti-1333	143	23	increased	increase	VERB
dti-1333	143	24	(	(	PUNCT
dti-1333	143	25	nicholls	nicholl	NOUN
dti-1333	143	26	et	et	PROPN
dti-1333	143	27	al	al	PROPN
dti-1333	143	28	.	.	PROPN
dti-1333	143	29	2007	2007	NUM
dti-1333	143	30	)	)	PUNCT
dti-1333	143	31	.	.	PUNCT
dti-1333	144	1	novel	novel	ADJ
dti-1333	144	2	drug	drug	NOUN
dti-1333	144	3	classes	class	NOUN
dti-1333	144	4	under	under	ADP
dti-1333	144	5	investigation	investigation	NOUN
dti-1333	144	6	hormone	hormone	NOUN
dti-1333	144	7	replacement	replacement	NOUN
dti-1333	144	8	therapy	therapy	NOUN
dti-1333	144	9	menopause	menopause	NOUN
dti-1333	144	10	is	be	AUX
dti-1333	144	11	a	a	DET
dti-1333	144	12	pro	pro	ADJ
dti-1333	144	13	-	-	ADJ
dti-1333	144	14	atherogenic	atherogenic	ADJ
dti-1333	144	15	state	state	NOUN
dti-1333	144	16	,	,	PUNCT
dti-1333	144	17	associated	associate	VERB
dti-1333	144	18	with	with	ADP
dti-1333	144	19	a	a	DET
dti-1333	144	20	signifi	signifi	NOUN
dti-1333	144	21	ca	can	AUX
dti-1333	144	22	nt	not	PART
dti-1333	144	23	increase	increase	VERB
dti-1333	144	24	in	in	ADP
dti-1333	144	25	the	the	DET
dti-1333	144	26	incidence	incidence	NOUN
dti-1333	144	27	of	of	ADP
dti-1333	144	28	coronary	coronary	ADJ
dti-1333	144	29	artery	artery	NOUN
dti-1333	144	30	disease	disease	NOUN
dti-1333	144	31	(	(	PUNCT
dti-1333	144	32	schnatz	schnatz	NOUN
dti-1333	144	33	and	and	CCONJ
dti-1333	144	34	schnatz	schnatz	PROPN
dti-1333	144	35	,	,	PUNCT
dti-1333	144	36	2006	2006	NUM
dti-1333	144	37	)	)	PUNCT
dti-1333	144	38	.	.	PUNCT
dti-1333	145	1	estrogen	estrogen	NOUN
dti-1333	145	2	replacement	replacement	NOUN
dti-1333	145	3	therapies	therapy	NOUN
dti-1333	145	4	,	,	PUNCT
dti-1333	145	5	such	such	ADJ
dti-1333	145	6	as	as	ADP
dti-1333	145	7	conjugated	conjugate	VERB
dti-1333	145	8	equine	equine	NOUN
dti-1333	145	9	estrogen	estrogen	NOUN
dti-1333	145	10	(	(	PUNCT
dti-1333	145	11	cee	cee	PROPN
dti-1333	145	12	,	,	PUNCT
dti-1333	145	13	premarin	premarin	PROPN
dti-1333	145	14	)	)	PUNCT
dti-1333	145	15	,	,	PUNCT
dti-1333	145	16	reduce	reduce	VERB
dti-1333	145	17	the	the	DET
dti-1333	145	18	risk	risk	NOUN
dti-1333	145	19	of	of	ADP
dti-1333	145	20	cad	cad	PROPN
dti-1333	145	21	in	in	ADP
dti-1333	145	22	postmenopausal	postmenopausal	ADJ
dti-1333	145	23	women	woman	NOUN
dti-1333	145	24	(	(	PUNCT
dti-1333	145	25	lamon	lamon	NOUN
dti-1333	145	26	-	-	PUNCT
dti-1333	145	27	fava	fava	NOUN
dti-1333	145	28	et	et	PROPN
dti-1333	145	29	al	al	PROPN
dti-1333	145	30	.	.	PROPN
dti-1333	145	31	2006	2006	NUM
dti-1333	145	32	)	)	PUNCT
dti-1333	145	33	.	.	PUNCT
dti-1333	146	1	hormone	hormone	NOUN
dti-1333	146	2	replacement	replacement	NOUN
dti-1333	146	3	therapy	therapy	NOUN
dti-1333	146	4	(	(	PUNCT
dti-1333	146	5	hrt	hrt	PROPN
dti-1333	146	6	)	)	PUNCT
dti-1333	146	7	is	be	AUX
dti-1333	146	8	associated	associate	VERB
dti-1333	146	9	with	with	ADP
dti-1333	146	10	increased	increase	VERB
dti-1333	146	11	apoa	apoa	NOUN
dti-1333	146	12	-	-	PUNCT
dti-1333	146	13	i	i	PROPN
dti-1333	146	14	and	and	CCONJ
dti-1333	146	15	hdl	hdl	PROPN
dti-1333	146	16	and	and	CCONJ
dti-1333	146	17	51	51	NUM
dti-1333	146	18	therapies	therapy	NOUN
dti-1333	146	19	to	to	PART
dti-1333	146	20	increase	increase	VERB
dti-1333	146	21	apoa-1	apoa-1	NUM
dti-1333	146	22	and	and	CCONJ
dti-1333	146	23	hdl	hdl	PROPN
dti-1333	146	24	-	-	PUNCT
dti-1333	146	25	cholesterol	cholesterol	NOUN
dti-1333	146	26	levels	level	NOUN
dti-1333	146	27	drug	drug	NOUN
dti-1333	146	28	target	target	NOUN
dti-1333	146	29	insights	insight	NOUN
dti-1333	146	30	2008:3	2008:3	NUM
dti-1333	146	31	decreased	decrease	VERB
dti-1333	146	32	ldl	ldl	NOUN
dti-1333	146	33	and	and	CCONJ
dti-1333	146	34	total	total	ADJ
dti-1333	146	35	cholesterol	cholesterol	NOUN
dti-1333	146	36	levels	level	NOUN
dti-1333	146	37	.	.	PUNCT
dti-1333	147	1	apoa	apoa	PROPN
dti-1333	147	2	-	-	PUNCT
dti-1333	147	3	i	i	PROPN
dti-1333	147	4	levels	level	NOUN
dti-1333	147	5	were	be	AUX
dti-1333	147	6	increased	increase	VERB
dti-1333	147	7	most	most	ADV
dti-1333	147	8	by	by	ADP
dti-1333	147	9	use	use	NOUN
dti-1333	147	10	of	of	ADP
dti-1333	147	11	estrogen	estrogen	NOUN
dti-1333	147	12	alone	alone	ADV
dti-1333	147	13	(	(	PUNCT
dti-1333	147	14	lamon	lamon	NOUN
dti-1333	147	15	-	-	PUNCT
dti-1333	147	16	fava	fava	NOUN
dti-1333	147	17	et	et	PROPN
dti-1333	147	18	al	al	PROPN
dti-1333	147	19	.	.	PROPN
dti-1333	147	20	2006	2006	NUM
dti-1333	147	21	)	)	PUNCT
dti-1333	147	22	.	.	PUNCT
dti-1333	148	1	rimonabant	rimonabant	PROPN
dti-1333	148	2	rimonabant	rimonabant	PROPN
dti-1333	148	3	,	,	PUNCT
dti-1333	148	4	a	a	DET
dti-1333	148	5	cannabinoid-1	cannabinoid-1	NUM
dti-1333	148	6	receptor	receptor	NOUN
dti-1333	148	7	blocker	blocker	NOUN
dti-1333	148	8	,	,	PUNCT
dti-1333	148	9	is	be	AUX
dti-1333	148	10	being	be	AUX
dti-1333	148	11	investigated	investigate	VERB
dti-1333	148	12	for	for	ADP
dti-1333	148	13	use	use	NOUN
dti-1333	148	14	in	in	ADP
dti-1333	148	15	reducing	reduce	VERB
dti-1333	148	16	body	body	NOUN
dti-1333	148	17	weight	weight	NOUN
dti-1333	148	18	and	and	CCONJ
dti-1333	148	19	improving	improve	VERB
dti-1333	148	20	cardiometabolic	cardiometabolic	ADJ
dti-1333	148	21	risk	risk	NOUN
dti-1333	148	22	factors	factor	NOUN
dti-1333	148	23	in	in	ADP
dti-1333	148	24	overweight	overweight	ADJ
dti-1333	148	25	or	or	CCONJ
dti-1333	148	26	obese	obese	ADJ
dti-1333	148	27	patients	patient	NOUN
dti-1333	148	28	(	(	PUNCT
dti-1333	148	29	forrester	forrester	PROPN
dti-1333	148	30	and	and	CCONJ
dti-1333	148	31	shah	shah	NOUN
dti-1333	148	32	,	,	PUNCT
dti-1333	148	33	2006	2006	NUM
dti-1333	148	34	)	)	PUNCT
dti-1333	148	35	.	.	PUNCT
dti-1333	149	1	in	in	ADP
dti-1333	149	2	one	one	NUM
dti-1333	149	3	randomized	randomize	VERB
dti-1333	149	4	,	,	PUNCT
dti-1333	149	5	controlled	control	VERB
dti-1333	149	6	trial	trial	NOUN
dti-1333	149	7	,	,	PUNCT
dti-1333	149	8	the	the	DET
dti-1333	149	9	mean	mean	ADJ
dti-1333	149	10	weight	weight	NOUN
dti-1333	149	11	loss	loss	NOUN
dti-1333	149	12	was	be	AUX
dti-1333	149	13	19	19	NUM
dti-1333	149	14	pounds	pound	NOUN
dti-1333	149	15	at	at	ADP
dti-1333	149	16	2	2	NUM
dti-1333	149	17	years	year	NOUN
dti-1333	149	18	.	.	PUNCT
dti-1333	150	1	in	in	ADP
dti-1333	150	2	the	the	DET
dti-1333	150	3	high	high	ADJ
dti-1333	150	4	-	-	PUNCT
dti-1333	150	5	dose	dose	NOUN
dti-1333	150	6	group	group	NOUN
dti-1333	150	7	,	,	PUNCT
dti-1333	150	8	39	39	NUM
dti-1333	150	9	%	%	NOUN
dti-1333	150	10	lost	lose	VERB
dti-1333	150	11	10	10	NUM
dti-1333	150	12	%	%	NOUN
dti-1333	150	13	of	of	ADP
dti-1333	150	14	their	their	PRON
dti-1333	150	15	initial	initial	ADJ
dti-1333	150	16	body	body	NOUN
dti-1333	150	17	weight	weight	NOUN
dti-1333	150	18	,	,	PUNCT
dti-1333	150	19	compared	compare	VERB
dti-1333	150	20	with	with	ADP
dti-1333	150	21	15	15	NUM
dti-1333	150	22	%	%	NOUN
dti-1333	150	23	in	in	ADP
dti-1333	150	24	the	the	DET
dti-1333	150	25	low	low	ADV
dti-1333	150	26	-	-	PUNCT
dti-1333	150	27	dose	dose	NOUN
dti-1333	150	28	cohort	cohort	NOUN
dti-1333	150	29	and	and	CCONJ
dti-1333	150	30	12	12	NUM
dti-1333	150	31	%	%	NOUN
dti-1333	150	32	of	of	ADP
dti-1333	150	33	those	those	PRON
dti-1333	150	34	receiving	receive	VERB
dti-1333	150	35	a	a	DET
dti-1333	150	36	placebo	placebo	NOUN
dti-1333	150	37	.	.	PUNCT
dti-1333	151	1	the	the	DET
dti-1333	151	2	number	number	NOUN
dti-1333	151	3	of	of	ADP
dti-1333	151	4	patients	patient	NOUN
dti-1333	151	5	with	with	ADP
dti-1333	151	6	metabolic	metabolic	NOUN
dti-1333	151	7	syndrome	syndrome	NOUN
dti-1333	151	8	at	at	ADP
dti-1333	151	9	baseline	baseline	PROPN
dti-1333	151	10	was	be	AUX
dti-1333	151	11	reduced	reduce	VERB
dti-1333	151	12	by	by	ADP
dti-1333	151	13	about	about	ADV
dti-1333	151	14	50	50	NUM
dti-1333	151	15	%	%	NOUN
dti-1333	151	16	with	with	ADP
dti-1333	151	17	rimonabant	rimonabant	ADJ
dti-1333	151	18	20	20	NUM
dti-1333	151	19	mg	mg	NOUN
dti-1333	151	20	.	.	PUNCT
dti-1333	152	1	concomitant	concomitant	ADJ
dti-1333	152	2	with	with	ADP
dti-1333	152	3	the	the	DET
dti-1333	152	4	weight	weight	NOUN
dti-1333	152	5	loss	loss	NOUN
dti-1333	152	6	,	,	PUNCT
dti-1333	152	7	the	the	DET
dti-1333	152	8	patients	patient	NOUN
dti-1333	152	9	exhibited	exhibit	VERB
dti-1333	152	10	an	an	DET
dti-1333	152	11	11	11	NUM
dti-1333	152	12	%	%	NOUN
dti-1333	152	13	decrease	decrease	NOUN
dti-1333	152	14	in	in	ADP
dti-1333	152	15	triglyceride	triglyceride	ADV
dti-1333	152	16	and	and	CCONJ
dti-1333	152	17	a	a	DET
dti-1333	152	18	27	27	NUM
dti-1333	152	19	%	%	NOUN
dti-1333	152	20	increase	increase	NOUN
dti-1333	152	21	in	in	ADP
dti-1333	152	22	hdl	hdl	PROPN
dti-1333	152	23	cholesterol	cholesterol	PROPN
dti-1333	152	24	(	(	PUNCT
dti-1333	152	25	forrester	forrester	PROPN
dti-1333	152	26	and	and	CCONJ
dti-1333	152	27	shah	shah	NOUN
dti-1333	152	28	,	,	PUNCT
dti-1333	152	29	2006	2006	NUM
dti-1333	152	30	)	)	PUNCT
dti-1333	152	31	.	.	PUNCT
dti-1333	153	1	this	this	DET
dti-1333	153	2	drug	drug	NOUN
dti-1333	153	3	is	be	AUX
dti-1333	153	4	currently	currently	ADV
dti-1333	153	5	approved	approve	VERB
dti-1333	153	6	in	in	ADP
dti-1333	153	7	many	many	ADJ
dti-1333	153	8	markets	market	NOUN
dti-1333	153	9	under	under	ADP
dti-1333	153	10	the	the	DET
dti-1333	153	11	brand	brand	NOUN
dti-1333	153	12	name	name	NOUN
dti-1333	153	13	acomplia	acomplia	NOUN
dti-1333	153	14	.	.	PUNCT
dti-1333	154	1	in	in	ADP
dti-1333	154	2	june	june	PROPN
dti-1333	154	3	2007	2007	NUM
dti-1333	154	4	,	,	PUNCT
dti-1333	154	5	the	the	DET
dti-1333	154	6	u.s	u.s	PROPN
dti-1333	154	7	.	.	PROPN
dti-1333	154	8	fda	fda	PROPN
dti-1333	154	9	’s	’s	PART
dti-1333	154	10	endocrinologic	endocrinologic	ADJ
dti-1333	154	11	and	and	CCONJ
dti-1333	154	12	metabolic	metabolic	NOUN
dti-1333	154	13	drugs	drug	NOUN
dti-1333	154	14	advisory	advisory	PROPN
dti-1333	154	15	committee	committee	NOUN
dti-1333	154	16	did	do	AUX
dti-1333	154	17	not	not	PART
dti-1333	154	18	recommend	recommend	VERB
dti-1333	154	19	approval	approval	NOUN
dti-1333	154	20	of	of	ADP
dti-1333	154	21	rimonabant	rimonabant	NOUN
dti-1333	154	22	for	for	ADP
dti-1333	154	23	weight	weight	NOUN
dti-1333	154	24	management	management	NOUN
dti-1333	154	25	.	.	PUNCT
dti-1333	155	1	cetp	cetp	NOUN
dti-1333	155	2	inhibitors	inhibitor	NOUN
dti-1333	155	3	cholesterol	cholesterol	NOUN
dti-1333	155	4	ester	ester	NOUN
dti-1333	155	5	transfer	transfer	NOUN
dti-1333	155	6	protein	protein	NOUN
dti-1333	155	7	(	(	PUNCT
dti-1333	155	8	cetp	cetp	PROPN
dti-1333	155	9	)	)	PUNCT
dti-1333	155	10	is	be	AUX
dti-1333	155	11	a	a	DET
dti-1333	155	12	glycoprotein	glycoprotein	NOUN
dti-1333	155	13	that	that	PRON
dti-1333	155	14	facilitates	facilitate	VERB
dti-1333	155	15	the	the	DET
dti-1333	155	16	transfer	transfer	NOUN
dti-1333	155	17	of	of	ADP
dti-1333	155	18	cholesteryl	cholesteryl	NOUN
dti-1333	155	19	esters	ester	NOUN
dti-1333	155	20	from	from	ADP
dti-1333	155	21	hdl	hdl	PROPN
dti-1333	155	22	-	-	PUNCT
dti-1333	155	23	c	c	NOUN
dti-1333	155	24	to	to	ADP
dti-1333	155	25	apo	apo	PROPN
dti-1333	155	26	b	b	X
dti-1333	155	27	-	-	PUNCT
dti-1333	155	28	containing	contain	VERB
dti-1333	155	29	lipoproteins	lipoprotein	NOUN
dti-1333	155	30	in	in	ADP
dti-1333	155	31	exchange	exchange	NOUN
dti-1333	155	32	for	for	ADP
dti-1333	155	33	triglycerides	triglyceride	NOUN
dti-1333	155	34	(	(	PUNCT
dti-1333	155	35	pal	pal	NOUN
dti-1333	155	36	and	and	CCONJ
dti-1333	155	37	pillarisetti	pillarisetti	NOUN
dti-1333	155	38	,	,	PUNCT
dti-1333	155	39	2007	2007	NUM
dti-1333	155	40	)	)	PUNCT
dti-1333	155	41	.	.	PUNCT
dti-1333	156	1	subjects	subject	NOUN
dti-1333	156	2	with	with	ADP
dti-1333	156	3	cetp	cetp	PROPN
dti-1333	156	4	defi	defi	PROPN
dti-1333	156	5	ciencies	ciencie	NOUN
dti-1333	156	6	,	,	PUNCT
dti-1333	156	7	because	because	SCONJ
dti-1333	156	8	of	of	ADP
dti-1333	156	9	cetp	cetp	NOUN
dti-1333	156	10	gene	gene	NOUN
dti-1333	156	11	defects	defect	NOUN
dti-1333	156	12	,	,	PUNCT
dti-1333	156	13	have	have	VERB
dti-1333	156	14	elevated	elevate	VERB
dti-1333	156	15	plasma	plasma	NOUN
dti-1333	156	16	levels	level	NOUN
dti-1333	156	17	of	of	ADP
dti-1333	156	18	hdl	hdl	PROPN
dti-1333	156	19	-	-	PUNCT
dti-1333	156	20	c	c	PROPN
dti-1333	156	21	and	and	CCONJ
dti-1333	156	22	apoa	apoa	PROPN
dti-1333	156	23	-	-	PUNCT
dti-1333	156	24	i.	i.	PROPN
dti-1333	156	25	however	however	ADV
dti-1333	156	26	the	the	DET
dti-1333	156	27	possibly	possibly	ADV
dti-1333	156	28	anti	anti	ADJ
dti-1333	156	29	-	-	ADJ
dti-1333	156	30	atherogenic	atherogenic	ADJ
dti-1333	156	31	role	role	NOUN
dti-1333	156	32	of	of	ADP
dti-1333	156	33	cetp	cetp	NOUN
dti-1333	156	34	is	be	AUX
dti-1333	156	35	complex	complex	ADJ
dti-1333	156	36	because	because	SCONJ
dti-1333	156	37	,	,	PUNCT
dti-1333	156	38	despite	despite	SCONJ
dti-1333	156	39	raising	raise	VERB
dti-1333	156	40	hdl	hdl	PROPN
dti-1333	156	41	-	-	PUNCT
dti-1333	156	42	c	c	NOUN
dti-1333	156	43	levels	level	NOUN
dti-1333	156	44	,	,	PUNCT
dti-1333	156	45	it	it	PRON
dti-1333	156	46	also	also	ADV
dti-1333	156	47	slows	slow	VERB
dti-1333	156	48	the	the	DET
dti-1333	156	49	metabolism	metabolism	NOUN
dti-1333	156	50	of	of	ADP
dti-1333	156	51	hdl	hdl	PROPN
dti-1333	156	52	-	-	PUNCT
dti-1333	156	53	c	c	PROPN
dti-1333	156	54	(	(	PUNCT
dti-1333	156	55	rader	rader	PROPN
dti-1333	156	56	,	,	PUNCT
dti-1333	156	57	2006	2006	NUM
dti-1333	156	58	,	,	PUNCT
dti-1333	156	59	2007a	2007a	NUM
dti-1333	156	60	)	)	PUNCT
dti-1333	156	61	.	.	PUNCT
dti-1333	157	1	to	to	ADP
dti-1333	157	2	date	date	NOUN
dti-1333	157	3	,	,	PUNCT
dti-1333	157	4	two	two	NUM
dti-1333	157	5	cetp	cetp	NOUN
dti-1333	157	6	inhibitors	inhibitor	NOUN
dti-1333	157	7	,	,	PUNCT
dti-1333	157	8	jtt-705	jtt-705	NOUN
dti-1333	157	9	and	and	CCONJ
dti-1333	157	10	torcetrapib	torcetrapib	ADV
dti-1333	157	11	,	,	PUNCT
dti-1333	157	12	have	have	AUX
dti-1333	157	13	been	be	AUX
dti-1333	157	14	evaluated	evaluate	VERB
dti-1333	157	15	clinically	clinically	ADV
dti-1333	157	16	and	and	CCONJ
dti-1333	157	17	have	have	AUX
dti-1333	157	18	shown	show	VERB
dti-1333	157	19	effi	effi	PROPN
dti-1333	157	20	cacy	cacy	NOUN
dti-1333	157	21	,	,	PUNCT
dti-1333	157	22	in	in	SCONJ
dti-1333	157	23	that	that	SCONJ
dti-1333	157	24	they	they	PRON
dti-1333	157	25	do	do	AUX
dti-1333	157	26	increase	increase	VERB
dti-1333	157	27	hdl	hdl	PROPN
dti-1333	157	28	-	-	PUNCT
dti-1333	157	29	c	c	PROPN
dti-1333	157	30	(	(	PUNCT
dti-1333	157	31	rader	rader	PROPN
dti-1333	157	32	,	,	PUNCT
dti-1333	157	33	2006	2006	NUM
dti-1333	157	34	,	,	PUNCT
dti-1333	157	35	2007a	2007a	NUM
dti-1333	157	36	;	;	PUNCT
dti-1333	157	37	barter	barter	NOUN
dti-1333	157	38	et	et	PROPN
dti-1333	157	39	al	al	PROPN
dti-1333	157	40	.	.	PROPN
dti-1333	157	41	2007	2007	NUM
dti-1333	157	42	)	)	PUNCT
dti-1333	157	43	.	.	PUNCT
dti-1333	158	1	in	in	ADP
dti-1333	158	2	early	early	ADJ
dti-1333	158	3	clinical	clinical	ADJ
dti-1333	158	4	studies	study	NOUN
dti-1333	158	5	,	,	PUNCT
dti-1333	158	6	torcetrapib	torcetrapib	ADV
dti-1333	158	7	showed	show	VERB
dti-1333	158	8	a	a	DET
dti-1333	158	9	pronounced	pronounced	ADJ
dti-1333	158	10	effect	effect	NOUN
dti-1333	158	11	on	on	ADP
dti-1333	158	12	plasma	plasma	NOUN
dti-1333	158	13	lipoproteins	lipoprotein	NOUN
dti-1333	158	14	in	in	ADP
dti-1333	158	15	patients	patient	NOUN
dti-1333	158	16	with	with	ADP
dti-1333	158	17	low	low	ADJ
dti-1333	158	18	hdl	hdl	PROPN
dti-1333	158	19	-	-	PUNCT
dti-1333	158	20	c	c	NOUN
dti-1333	158	21	levels	level	NOUN
dti-1333	158	22	,	,	PUNCT
dti-1333	158	23	and	and	CCONJ
dti-1333	158	24	reduced	reduce	VERB
dti-1333	158	25	the	the	DET
dti-1333	158	26	levels	level	NOUN
dti-1333	158	27	of	of	ADP
dti-1333	158	28	ldl	ldl	NOUN
dti-1333	158	29	-	-	PUNCT
dti-1333	158	30	c	c	NOUN
dti-1333	158	31	and	and	CCONJ
dti-1333	158	32	apolipoprotein	apolipoprotein	ADJ
dti-1333	158	33	b	b	PROPN
dti-1333	158	34	,	,	PUNCT
dti-1333	158	35	both	both	PRON
dti-1333	158	36	as	as	ADP
dti-1333	158	37	a	a	DET
dti-1333	158	38	monotherapy	monotherapy	NOUN
dti-1333	158	39	and	and	CCONJ
dti-1333	158	40	in	in	ADP
dti-1333	158	41	combination	combination	NOUN
dti-1333	158	42	with	with	ADP
dti-1333	158	43	atorvastatin	atorvastatin	NOUN
dti-1333	158	44	(	(	PUNCT
dti-1333	158	45	rader	rader	PROPN
dti-1333	158	46	,	,	PUNCT
dti-1333	158	47	2006	2006	NUM
dti-1333	158	48	,	,	PUNCT
dti-1333	158	49	2007a	2007a	NUM
dti-1333	158	50	)	)	PUNCT
dti-1333	158	51	.	.	PUNCT
dti-1333	159	1	after	after	ADP
dti-1333	159	2	the	the	DET
dti-1333	159	3	phase	phase	NOUN
dti-1333	159	4	ii	ii	PROPN
dti-1333	159	5	dose	dose	NOUN
dti-1333	159	6	-	-	PUNCT
dti-1333	159	7	ranging	range	VERB
dti-1333	159	8	trials	trial	NOUN
dti-1333	159	9	,	,	PUNCT
dti-1333	159	10	torcetrapib	torcetrapib	ADV
dti-1333	159	11	,	,	PUNCT
dti-1333	159	12	despite	despite	SCONJ
dti-1333	159	13	being	be	AUX
dti-1333	159	14	associated	associate	VERB
dti-1333	159	15	with	with	ADP
dti-1333	159	16	a	a	DET
dti-1333	159	17	substantial	substantial	ADJ
dti-1333	159	18	increase	increase	NOUN
dti-1333	159	19	in	in	ADP
dti-1333	159	20	hdl	hdl	PROPN
dti-1333	159	21	-	-	PUNCT
dti-1333	159	22	c	c	PROPN
dti-1333	159	23	and	and	CCONJ
dti-1333	159	24	decrease	decrease	NOUN
dti-1333	159	25	in	in	ADP
dti-1333	159	26	ldl	ldl	NOUN
dti-1333	159	27	cholesterol	cholesterol	NOUN
dti-1333	159	28	,	,	PUNCT
dti-1333	159	29	was	be	AUX
dti-1333	159	30	also	also	ADV
dti-1333	159	31	associated	associate	VERB
dti-1333	159	32	with	with	ADP
dti-1333	159	33	an	an	DET
dti-1333	159	34	increase	increase	NOUN
dti-1333	159	35	in	in	ADP
dti-1333	159	36	blood	blood	NOUN
dti-1333	159	37	pressure	pressure	NOUN
dti-1333	159	38	,	,	PUNCT
dti-1333	159	39	and	and	CCONJ
dti-1333	159	40	no	no	DET
dti-1333	159	41	decrease	decrease	NOUN
dti-1333	159	42	in	in	ADP
dti-1333	159	43	the	the	DET
dti-1333	159	44	progression	progression	NOUN
dti-1333	159	45	of	of	ADP
dti-1333	159	46	coronary	coronary	ADJ
dti-1333	159	47	atherosclerosis	atherosclerosis	NOUN
dti-1333	159	48	(	(	PUNCT
dti-1333	159	49	nissen	nissen	PROPN
dti-1333	159	50	et	et	PROPN
dti-1333	159	51	al	al	PROPN
dti-1333	159	52	.	.	PROPN
dti-1333	159	53	2007b	2007b	NUM
dti-1333	159	54	)	)	PUNCT
dti-1333	159	55	.	.	PUNCT
dti-1333	160	1	the	the	DET
dti-1333	160	2	lack	lack	NOUN
dti-1333	160	3	of	of	ADP
dti-1333	160	4	effi	effi	PROPN
dti-1333	160	5	cacy	cacy	NOUN
dti-1333	160	6	may	may	AUX
dti-1333	160	7	be	be	AUX
dti-1333	160	8	related	relate	VERB
dti-1333	160	9	to	to	ADP
dti-1333	160	10	the	the	DET
dti-1333	160	11	mechanism	mechanism	NOUN
dti-1333	160	12	of	of	ADP
dti-1333	160	13	action	action	NOUN
dti-1333	160	14	of	of	ADP
dti-1333	160	15	this	this	DET
dti-1333	160	16	drug	drug	NOUN
dti-1333	160	17	class	class	NOUN
dti-1333	160	18	or	or	CCONJ
dti-1333	160	19	to	to	ADP
dti-1333	160	20	molecule	molecule	NOUN
dti-1333	160	21	-	-	PUNCT
dti-1333	160	22	specifi	specifi	PROPN
dti-1333	160	23	c	c	PROPN
dti-1333	160	24	adverse	adverse	ADJ
dti-1333	160	25	effects	effect	NOUN
dti-1333	160	26	(	(	PUNCT
dti-1333	160	27	rader	rader	NOUN
dti-1333	160	28	,	,	PUNCT
dti-1333	160	29	2007b	2007b	NUM
dti-1333	160	30	;	;	PUNCT
dti-1333	160	31	barter	barter	NOUN
dti-1333	160	32	et	et	PROPN
dti-1333	160	33	al	al	PROPN
dti-1333	160	34	.	.	PROPN
dti-1333	160	35	2007	2007	NUM
dti-1333	160	36	)	)	PUNCT
dti-1333	160	37	.	.	PUNCT
dti-1333	161	1	after	after	ADP
dti-1333	161	2	demonstrating	demonstrate	VERB
dti-1333	161	3	effi	effi	PROPN
dti-1333	161	4	cacy	cacy	NOUN
dti-1333	161	5	in	in	ADP
dti-1333	161	6	phase	phase	NOUN
dti-1333	161	7	ii	ii	PROPN
dti-1333	161	8	,	,	PUNCT
dti-1333	161	9	no	no	DET
dti-1333	161	10	additional	additional	ADJ
dti-1333	161	11	data	datum	NOUN
dti-1333	161	12	has	have	AUX
dti-1333	161	13	yet	yet	ADV
dti-1333	161	14	been	be	AUX
dti-1333	161	15	published	publish	VERB
dti-1333	161	16	on	on	ADP
dti-1333	161	17	jtt-705	jtt-705	NOUN
dti-1333	161	18	.	.	PUNCT
dti-1333	162	1	agi-1067	agi-1067	PROPN
dti-1333	162	2	infl	infl	PROPN
dti-1333	162	3	ammation	ammation	PROPN
dti-1333	162	4	has	have	VERB
dti-1333	162	5	a	a	DET
dti-1333	162	6	fundamental	fundamental	ADJ
dti-1333	162	7	role	role	NOUN
dti-1333	162	8	in	in	ADP
dti-1333	162	9	mediating	mediate	VERB
dti-1333	162	10	all	all	DET
dti-1333	162	11	stages	stage	NOUN
dti-1333	162	12	of	of	ADP
dti-1333	162	13	atherosclerotic	atherosclerotic	ADJ
dti-1333	162	14	disease	disease	NOUN
dti-1333	162	15	.	.	PUNCT
dti-1333	163	1	agi-1067	agi-1067	PROPN
dti-1333	163	2	(	(	PUNCT
dti-1333	163	3	probucol	probucol	PROPN
dti-1333	163	4	monosuccinate	monosuccinate	PROPN
dti-1333	163	5	,	,	PUNCT
dti-1333	163	6	succinobucol	succinobucol	NOUN
dti-1333	163	7	)	)	PUNCT
dti-1333	163	8	is	be	AUX
dti-1333	163	9	being	be	AUX
dti-1333	163	10	assessed	assess	VERB
dti-1333	163	11	for	for	ADP
dti-1333	163	12	the	the	DET
dti-1333	163	13	treatment	treatment	NOUN
dti-1333	163	14	of	of	ADP
dti-1333	163	15	restenosis	restenosis	NOUN
dti-1333	163	16	and	and	CCONJ
dti-1333	163	17	possibly	possibly	ADV
dti-1333	163	18	atherosclerosis	atherosclerosis	NOUN
dti-1333	163	19	.	.	PUNCT
dti-1333	164	1	the	the	DET
dti-1333	164	2	pharmacological	pharmacological	ADJ
dti-1333	164	3	activities	activity	NOUN
dti-1333	164	4	of	of	ADP
dti-1333	164	5	agi-1067	agi-1067	NOUN
dti-1333	164	6	are	be	AUX
dti-1333	164	7	the	the	DET
dti-1333	164	8	ability	ability	NOUN
dti-1333	164	9	to	to	PART
dti-1333	164	10	block	block	VERB
dti-1333	164	11	the	the	DET
dti-1333	164	12	expression	expression	NOUN
dti-1333	164	13	of	of	ADP
dti-1333	164	14	oxidation	oxidation	NOUN
dti-1333	164	15	-	-	PUNCT
dti-1333	164	16	sensitive	sensitive	ADJ
dti-1333	164	17	infl	infl	PROPN
dti-1333	164	18	ammatory	ammatory	NOUN
dti-1333	164	19	genes	gene	NOUN
dti-1333	164	20	,	,	PUNCT
dti-1333	164	21	including	include	VERB
dti-1333	164	22	genes	gene	NOUN
dti-1333	164	23	that	that	PRON
dti-1333	164	24	encode	encode	VERB
dti-1333	164	25	vascular	vascular	ADJ
dti-1333	164	26	cell	cell	NOUN
dti-1333	164	27	adhesion	adhesion	NOUN
dti-1333	164	28	molecule-1	molecule-1	PROPN
dti-1333	164	29	and	and	CCONJ
dti-1333	164	30	monocyte	monocyte	ADJ
dti-1333	164	31	chemotactic	chemotactic	ADJ
dti-1333	164	32	protein-1	protein-1	PROPN
dti-1333	164	33	.	.	PUNCT
dti-1333	165	1	in	in	ADP
dti-1333	165	2	a	a	DET
dti-1333	165	3	placebo	placebo	NOUN
dti-1333	165	4	-	-	PUNCT
dti-1333	165	5	controlled	control	VERB
dti-1333	165	6	,	,	PUNCT
dti-1333	165	7	randomized	randomized	ADJ
dti-1333	165	8	study	study	NOUN
dti-1333	165	9	of	of	ADP
dti-1333	165	10	the	the	DET
dti-1333	165	11	effects	effect	NOUN
dti-1333	165	12	of	of	ADP
dti-1333	165	13	agi-1067	agi-1067	NOUN
dti-1333	165	14	on	on	ADP
dti-1333	165	15	coronary	coronary	ADJ
dti-1333	165	16	atherosclerosis	atherosclerosis	NOUN
dti-1333	165	17	,	,	PUNCT
dti-1333	165	18	some	some	DET
dti-1333	165	19	regression	regression	NOUN
dti-1333	165	20	was	be	AUX
dti-1333	165	21	observed	observe	VERB
dti-1333	165	22	in	in	ADP
dti-1333	165	23	patients	patient	NOUN
dti-1333	165	24	treated	treat	VERB
dti-1333	165	25	with	with	ADP
dti-1333	165	26	agi-1067	agi-1067	NOUN
dti-1333	165	27	,	,	PUNCT
dti-1333	165	28	but	but	CCONJ
dti-1333	165	29	it	it	PRON
dti-1333	165	30	was	be	AUX
dti-1333	165	31	not	not	PART
dti-1333	165	32	signifi	signifi	VERB
dti-1333	165	33	cantly	cantly	ADV
dti-1333	165	34	different	different	ADJ
dti-1333	165	35	from	from	ADP
dti-1333	165	36	placebo	placebo	NOUN
dti-1333	165	37	.	.	PUNCT
dti-1333	166	1	moreover	moreover	ADV
dti-1333	166	2	,	,	PUNCT
dti-1333	166	3	hdl	hdl	PROPN
dti-1333	166	4	-	-	PUNCT
dti-1333	166	5	c	c	PROPN
dti-1333	166	6	was	be	AUX
dti-1333	166	7	reduced	reduce	VERB
dti-1333	166	8	by	by	ADP
dti-1333	166	9	14	14	NUM
dti-1333	166	10	%	%	NOUN
dti-1333	166	11	with	with	ADP
dti-1333	166	12	agi-1067	agi-1067	NOUN
dti-1333	166	13	treatment	treatment	NOUN
dti-1333	166	14	and	and	CCONJ
dti-1333	166	15	1	1	NUM
dti-1333	166	16	%	%	NOUN
dti-1333	166	17	with	with	ADP
dti-1333	166	18	placebo	placebo	NOUN
dti-1333	166	19	(	(	PUNCT
dti-1333	166	20	tardif	tardif	PROPN
dti-1333	166	21	et	et	PROPN
dti-1333	166	22	al	al	PROPN
dti-1333	166	23	.	.	PROPN
dti-1333	166	24	2007a	2007a	NUM
dti-1333	166	25	)	)	PUNCT
dti-1333	166	26	.	.	PUNCT
dti-1333	167	1	phospholipids	phospholipid	NOUN
dti-1333	167	2	phosphatidylinositol	phosphatidylinositol	NOUN
dti-1333	167	3	can	can	AUX
dti-1333	167	4	stimulate	stimulate	VERB
dti-1333	167	5	reverse	reverse	ADJ
dti-1333	167	6	cholesterol	cholesterol	NOUN
dti-1333	167	7	transport	transport	NOUN
dti-1333	167	8	by	by	ADP
dti-1333	167	9	enhancing	enhance	VERB
dti-1333	167	10	the	the	DET
dti-1333	167	11	fl	fl	NOUN
dti-1333	167	12	ux	ux	PROPN
dti-1333	167	13	of	of	ADP
dti-1333	167	14	cholesterol	cholesterol	NOUN
dti-1333	167	15	into	into	ADP
dti-1333	167	16	hdl	hdl	PROPN
dti-1333	167	17	and	and	CCONJ
dti-1333	167	18	by	by	ADP
dti-1333	167	19	promoting	promote	VERB
dti-1333	167	20	the	the	DET
dti-1333	167	21	transport	transport	NOUN
dti-1333	167	22	of	of	ADP
dti-1333	167	23	hdl	hdl	PROPN
dti-1333	167	24	-	-	PUNCT
dti-1333	167	25	c	c	PROPN
dti-1333	167	26	to	to	ADP
dti-1333	167	27	the	the	DET
dti-1333	167	28	liver	liver	NOUN
dti-1333	167	29	and	and	CCONJ
dti-1333	167	30	bile	bile	NOUN
dti-1333	167	31	.	.	PUNCT
dti-1333	168	1	currently	currently	ADV
dti-1333	168	2	,	,	PUNCT
dti-1333	168	3	phosphatidylinositol	phosphatidylinositol	NOUN
dti-1333	168	4	(	(	PUNCT
dti-1333	168	5	pi	pi	NOUN
dti-1333	168	6	)	)	PUNCT
dti-1333	168	7	is	be	AUX
dti-1333	168	8	being	be	AUX
dti-1333	168	9	evaluated	evaluate	VERB
dti-1333	168	10	in	in	ADP
dti-1333	168	11	human	human	ADJ
dti-1333	168	12	subjects	subject	NOUN
dti-1333	168	13	.	.	PUNCT
dti-1333	169	1	at	at	ADP
dti-1333	169	2	doses	dose	NOUN
dti-1333	169	3	as	as	ADV
dti-1333	169	4	high	high	ADJ
dti-1333	169	5	as	as	ADP
dti-1333	169	6	5.6	5.6	NUM
dti-1333	169	7	g	g	NOUN
dti-1333	169	8	/	/	SYM
dti-1333	169	9	day	day	NOUN
dti-1333	169	10	,	,	PUNCT
dti-1333	169	11	pi	pi	NOUN
dti-1333	169	12	demonstrated	demonstrate	VERB
dti-1333	169	13	increases	increase	NOUN
dti-1333	169	14	of	of	ADP
dti-1333	169	15	hdl	hdl	NOUN
dti-1333	169	16	-	-	PUNCT
dti-1333	169	17	c	c	PROPN
dti-1333	169	18	of	of	ADP
dti-1333	169	19	18	18	NUM
dti-1333	169	20	%	%	NOUN
dti-1333	169	21	over	over	ADP
dti-1333	169	22	a	a	DET
dti-1333	169	23	2	2	NUM
dti-1333	169	24	-	-	PUNCT
dti-1333	169	25	week	week	NOUN
dti-1333	169	26	period	period	NOUN
dti-1333	169	27	,	,	PUNCT
dti-1333	169	28	and	and	CCONJ
dti-1333	169	29	a	a	DET
dti-1333	169	30	decrease	decrease	NOUN
dti-1333	169	31	in	in	ADP
dti-1333	169	32	triglycerides	triglyceride	NOUN
dti-1333	169	33	by	by	ADP
dti-1333	169	34	36	36	NUM
dti-1333	169	35	%	%	NOUN
dti-1333	169	36	in	in	ADP
dti-1333	169	37	fed	fed	PROPN
dti-1333	169	38	subjects	subject	NOUN
dti-1333	169	39	.	.	PUNCT
dti-1333	170	1	this	this	DET
dti-1333	170	2	product	product	NOUN
dti-1333	170	3	is	be	AUX
dti-1333	170	4	in	in	ADP
dti-1333	170	5	clinical	clinical	ADJ
dti-1333	170	6	development	development	NOUN
dti-1333	170	7	(	(	PUNCT
dti-1333	170	8	burgess	burgess	NOUN
dti-1333	170	9	et	et	PROPN
dti-1333	170	10	al	al	PROPN
dti-1333	170	11	.	.	PROPN
dti-1333	170	12	2005	2005	NUM
dti-1333	170	13	)	)	PUNCT
dti-1333	170	14	.	.	PUNCT
dti-1333	171	1	csl-111	csl-111	PROPN
dti-1333	171	2	is	be	AUX
dti-1333	171	3	a	a	DET
dti-1333	171	4	reconstituted	reconstitute	VERB
dti-1333	171	5	hdl	hdl	NOUN
dti-1333	171	6	,	,	PUNCT
dti-1333	171	7	consisting	consist	VERB
dti-1333	171	8	of	of	ADP
dti-1333	171	9	apoa	apoa	NOUN
dti-1333	171	10	-	-	PUNCT
dti-1333	171	11	i	i	PROPN
dti-1333	171	12	from	from	ADP
dti-1333	171	13	human	human	ADJ
dti-1333	171	14	plasma	plasma	NOUN
dti-1333	171	15	combined	combine	VERB
dti-1333	171	16	with	with	ADP
dti-1333	171	17	soybean	soybean	NOUN
dti-1333	171	18	phosphatidylcholine	phosphatidylcholine	NOUN
dti-1333	171	19	,	,	PUNCT
dti-1333	171	20	that	that	PRON
dti-1333	171	21	resembles	resemble	VERB
dti-1333	171	22	native	native	ADJ
dti-1333	171	23	hdl	hdl	PROPN
dti-1333	172	1	(	(	PUNCT
dti-1333	172	2	tardiff	tardiff	NOUN
dti-1333	172	3	et	et	PROPN
dti-1333	172	4	al	al	PROPN
dti-1333	172	5	.	.	PROPN
dti-1333	172	6	2007b	2007b	NUM
dti-1333	172	7	)	)	PUNCT
dti-1333	172	8	.	.	PUNCT
dti-1333	173	1	in	in	ADP
dti-1333	173	2	a	a	DET
dti-1333	173	3	183	183	NUM
dti-1333	173	4	-	-	PUNCT
dti-1333	173	5	patient	patient	NOUN
dti-1333	173	6	phase	phase	NOUN
dti-1333	173	7	ii	ii	NOUN
dti-1333	173	8	clinical	clinical	ADJ
dti-1333	173	9	trial	trial	NOUN
dti-1333	173	10	,	,	PUNCT
dti-1333	173	11	there	there	PRON
dti-1333	173	12	was	be	VERB
dti-1333	173	13	no	no	DET
dti-1333	173	14	signifi	signifi	NOUN
dti-1333	173	15	ca	can	AUX
dti-1333	173	16	nt	not	PART
dti-1333	173	17	reduction	reduction	VERB
dti-1333	173	18	in	in	ADP
dti-1333	173	19	atheroma	atheroma	NOUN
dti-1333	173	20	or	or	CCONJ
dti-1333	173	21	plaque	plaque	NOUN
dti-1333	173	22	volume	volume	NOUN
dti-1333	173	23	,	,	PUNCT
dti-1333	173	24	compared	compare	VERB
dti-1333	173	25	with	with	ADP
dti-1333	173	26	the	the	DET
dti-1333	173	27	placebo	placebo	NOUN
dti-1333	173	28	,	,	PUNCT
dti-1333	173	29	but	but	CCONJ
dti-1333	173	30	there	there	PRON
dti-1333	173	31	was	be	VERB
dti-1333	173	32	a	a	DET
dti-1333	173	33	statistically	statistically	ADV
dti-1333	173	34	signifi	signifi	NOUN
dti-1333	173	35	ca	can	AUX
dti-1333	173	36	nt	not	PART
dti-1333	173	37	improvement	improvement	VERB
dti-1333	173	38	in	in	ADP
dti-1333	173	39	the	the	DET
dti-1333	173	40	plaque	plaque	NOUN
dti-1333	173	41	characterization	characterization	NOUN
dti-1333	173	42	index	index	NOUN
dti-1333	173	43	and	and	CCONJ
dti-1333	173	44	coronary	coronary	ADJ
dti-1333	173	45	score	score	NOUN
dti-1333	173	46	on	on	ADP
dti-1333	173	47	quantitative	quantitative	ADJ
dti-1333	173	48	coronary	coronary	ADJ
dti-1333	173	49	angiography	angiography	NOUN
dti-1333	173	50	(	(	PUNCT
dti-1333	173	51	tardiff	tardiff	NOUN
dti-1333	173	52	et	et	PROPN
dti-1333	173	53	al	al	PROPN
dti-1333	173	54	.	.	PROPN
dti-1333	173	55	2007b	2007b	NUM
dti-1333	173	56	)	)	PUNCT
dti-1333	173	57	.	.	PUNCT
dti-1333	174	1	conclusions	conclusion	NOUN
dti-1333	174	2	the	the	DET
dti-1333	174	3	lipid	lipid	ADJ
dti-1333	174	4	hypothesis	hypothesis	NOUN
dti-1333	174	5	,	,	PUNCT
dti-1333	174	6	now	now	ADV
dti-1333	174	7	more	more	ADJ
dti-1333	174	8	than	than	ADP
dti-1333	174	9	100	100	NUM
dti-1333	174	10	years	year	NOUN
dti-1333	174	11	old	old	ADJ
dti-1333	174	12	,	,	PUNCT
dti-1333	174	13	is	be	AUX
dti-1333	174	14	based	base	VERB
dti-1333	174	15	on	on	ADP
dti-1333	174	16	the	the	DET
dti-1333	174	17	idea	idea	NOUN
dti-1333	174	18	that	that	PRON
dti-1333	174	19	dyslipidemia	dyslipidemia	NOUN
dti-1333	174	20	is	be	AUX
dti-1333	174	21	central	central	ADJ
dti-1333	174	22	to	to	ADP
dti-1333	174	23	52	52	NUM
dti-1333	174	24	brown	brown	ADJ
dti-1333	174	25	and	and	CCONJ
dti-1333	174	26	chiacchia	chiacchia	PROPN
dti-1333	174	27	drug	drug	NOUN
dti-1333	174	28	target	target	NOUN
dti-1333	174	29	insights	insight	NOUN
dti-1333	174	30	2008:3	2008:3	NUM
dti-1333	174	31	atherosclerosis	atherosclerosis	NOUN
dti-1333	174	32	.	.	PUNCT
dti-1333	175	1	its	its	PRON
dti-1333	175	2	validity	validity	NOUN
dti-1333	175	3	was	be	AUX
dti-1333	175	4	ultimately	ultimately	ADV
dti-1333	175	5	demonstrated	demonstrate	VERB
dti-1333	175	6	by	by	ADP
dti-1333	175	7	major	major	ADJ
dti-1333	175	8	epidemiological	epidemiological	ADJ
dti-1333	175	9	studies	study	NOUN
dti-1333	175	10	,	,	PUNCT
dti-1333	175	11	demonstrating	demonstrate	VERB
dti-1333	175	12	that	that	SCONJ
dti-1333	175	13	cholesterol	cholesterol	NOUN
dti-1333	175	14	levels	level	NOUN
dti-1333	175	15	were	be	AUX
dti-1333	175	16	linearly	linearly	ADV
dti-1333	175	17	related	relate	VERB
dti-1333	175	18	to	to	ADP
dti-1333	175	19	coronary	coronary	ADJ
dti-1333	175	20	heart	heart	NOUN
dti-1333	175	21	disease	disease	NOUN
dti-1333	175	22	mortality	mortality	NOUN
dti-1333	175	23	.	.	PUNCT
dti-1333	176	1	further	further	ADJ
dti-1333	176	2	epidemiological	epidemiological	ADJ
dti-1333	176	3	studies	study	NOUN
dti-1333	176	4	showed	show	VERB
dti-1333	176	5	an	an	DET
dti-1333	176	6	inverse	inverse	NOUN
dti-1333	176	7	relationship	relationship	NOUN
dti-1333	176	8	between	between	ADP
dti-1333	176	9	blood	blood	NOUN
dti-1333	176	10	levels	level	NOUN
dti-1333	176	11	of	of	ADP
dti-1333	176	12	hdl	hdl	PROPN
dti-1333	176	13	-	-	PUNCT
dti-1333	176	14	c	c	PROPN
dti-1333	176	15	and	and	CCONJ
dti-1333	176	16	the	the	DET
dti-1333	176	17	incidence	incidence	NOUN
dti-1333	176	18	of	of	ADP
dti-1333	176	19	clinically	clinically	ADV
dti-1333	176	20	signifi	signifi	NOUN
dti-1333	176	21	ca	can	AUX
dti-1333	176	22	nt	not	PART
dti-1333	176	23	atherosclerosis	atherosclerosis	VERB
dti-1333	176	24	;	;	PUNCT
dti-1333	176	25	it	it	PRON
dti-1333	176	26	appears	appear	VERB
dti-1333	176	27	that	that	SCONJ
dti-1333	176	28	each	each	DET
dti-1333	176	29	1	1	NUM
dti-1333	176	30	mg	mg	PROPN
dti-1333	176	31	/	/	SYM
dti-1333	176	32	dl	dl	PROPN
dti-1333	176	33	increment	increment	NOUN
dti-1333	176	34	in	in	ADP
dti-1333	176	35	serum	serum	NOUN
dti-1333	176	36	hdl	hdl	PROPN
dti-1333	176	37	-	-	PUNCT
dti-1333	176	38	c	c	PROPN
dti-1333	176	39	is	be	AUX
dti-1333	176	40	associated	associate	VERB
dti-1333	176	41	with	with	ADP
dti-1333	176	42	a	a	DET
dti-1333	176	43	2%–3	2%–3	NUM
dti-1333	176	44	%	%	NOUN
dti-1333	176	45	decrement	decrement	NOUN
dti-1333	176	46	in	in	ADP
dti-1333	176	47	cardiovascular	cardiovascular	ADJ
dti-1333	176	48	risk	risk	NOUN
dti-1333	176	49	(	(	PUNCT
dti-1333	176	50	boden	boden	PROPN
dti-1333	176	51	,	,	PUNCT
dti-1333	176	52	2000	2000	NUM
dti-1333	176	53	)	)	PUNCT
dti-1333	176	54	.	.	PUNCT
dti-1333	177	1	while	while	SCONJ
dti-1333	177	2	our	our	PRON
dti-1333	177	3	understanding	understanding	NOUN
dti-1333	177	4	of	of	ADP
dti-1333	177	5	the	the	DET
dti-1333	177	6	mechanism(s	mechanism(s	NOUN
dti-1333	177	7	)	)	PUNCT
dti-1333	177	8	by	by	ADP
dti-1333	177	9	which	which	PRON
dti-1333	177	10	hdl	hdl	PROPN
dti-1333	177	11	alters	alter	VERB
dti-1333	177	12	atherosclerotic	atherosclerotic	ADJ
dti-1333	177	13	disease	disease	NOUN
dti-1333	177	14	remain(s	remain(s	PROPN
dti-1333	177	15	)	)	PUNCT
dti-1333	177	16	incomplete	incomplete	ADJ
dti-1333	177	17	,	,	PUNCT
dti-1333	177	18	it	it	PRON
dti-1333	177	19	is	be	AUX
dti-1333	177	20	believed	believe	VERB
dti-1333	177	21	that	that	SCONJ
dti-1333	177	22	elevated	elevated	ADJ
dti-1333	177	23	levels	level	NOUN
dti-1333	177	24	of	of	ADP
dti-1333	177	25	hdl	hdl	PROPN
dti-1333	177	26	increase	increase	VERB
dti-1333	177	27	the	the	DET
dti-1333	177	28	transport	transport	NOUN
dti-1333	177	29	of	of	ADP
dti-1333	177	30	cholesterol	cholesterol	NOUN
dti-1333	177	31	from	from	ADP
dti-1333	177	32	arteries	artery	NOUN
dti-1333	177	33	and	and	CCONJ
dti-1333	177	34	tissues	tissue	NOUN
dti-1333	177	35	to	to	ADP
dti-1333	177	36	the	the	DET
dti-1333	177	37	liver	liver	NOUN
dti-1333	177	38	for	for	ADP
dti-1333	177	39	excretion	excretion	NOUN
dti-1333	177	40	.	.	PUNCT
dti-1333	178	1	based	base	VERB
dti-1333	178	2	on	on	ADP
dti-1333	178	3	the	the	DET
dti-1333	178	4	rct	rct	PROPN
dti-1333	178	5	model	model	NOUN
dti-1333	178	6	(	(	PUNCT
dti-1333	178	7	fig	fig	NOUN
dti-1333	178	8	.	.	NOUN
dti-1333	178	9	1	1	NUM
dti-1333	178	10	)	)	PUNCT
dti-1333	178	11	,	,	PUNCT
dti-1333	178	12	apoa	apoa	NOUN
dti-1333	178	13	-	-	PUNCT
dti-1333	178	14	i	i	PRON
dti-1333	178	15	is	be	AUX
dti-1333	178	16	an	an	DET
dti-1333	178	17	attractive	attractive	ADJ
dti-1333	178	18	target	target	NOUN
dti-1333	178	19	for	for	ADP
dti-1333	178	20	therapeutic	therapeutic	ADJ
dti-1333	178	21	intervention	intervention	NOUN
dti-1333	178	22	.	.	PUNCT
dti-1333	179	1	experimental	experimental	ADJ
dti-1333	179	2	manipulations	manipulation	NOUN
dti-1333	179	3	to	to	PART
dti-1333	179	4	increase	increase	VERB
dti-1333	179	5	apoa	apoa	NOUN
dti-1333	179	6	-	-	PUNCT
dti-1333	179	7	i	i	PRON
dti-1333	179	8	have	have	AUX
dti-1333	179	9	been	be	AUX
dti-1333	179	10	shown	show	VERB
dti-1333	179	11	to	to	PART
dti-1333	179	12	reduce	reduce	VERB
dti-1333	179	13	atherogenicity	atherogenicity	NOUN
dti-1333	179	14	.	.	PUNCT
dti-1333	180	1	human	human	ADJ
dti-1333	180	2	apoa	apoa	PROPN
dti-1333	180	3	-	-	PUNCT
dti-1333	180	4	i	i	PRON
dti-1333	180	5	is	be	AUX
dti-1333	180	6	protective	protective	ADJ
dti-1333	180	7	in	in	ADP
dti-1333	180	8	transgenic	transgenic	NOUN
dti-1333	180	9	animal	animal	NOUN
dti-1333	180	10	models	model	NOUN
dti-1333	180	11	(	(	PUNCT
dti-1333	180	12	shah	shah	PROPN
dti-1333	180	13	et	et	PROPN
dti-1333	180	14	al	al	PROPN
dti-1333	180	15	.	.	PROPN
dti-1333	180	16	1998	1998	NUM
dti-1333	180	17	;	;	PUNCT
dti-1333	180	18	rubin	rubin	PROPN
dti-1333	180	19	et	et	PROPN
dti-1333	180	20	al	al	PROPN
dti-1333	180	21	.	.	PROPN
dti-1333	180	22	1991	1991	NUM
dti-1333	180	23	)	)	PUNCT
dti-1333	180	24	and	and	CCONJ
dti-1333	180	25	infusion	infusion	NOUN
dti-1333	180	26	of	of	ADP
dti-1333	180	27	apoa	apoa	NOUN
dti-1333	180	28	-	-	PUNCT
dti-1333	180	29	imilano	imilano	PROPN
dti-1333	180	30	prevents	prevent	VERB
dti-1333	180	31	atherosclerotic	atherosclerotic	ADJ
dti-1333	180	32	lesions	lesion	NOUN
dti-1333	180	33	and	and	CCONJ
dti-1333	180	34	leads	lead	VERB
dti-1333	180	35	to	to	ADP
dti-1333	180	36	regression	regression	NOUN
dti-1333	180	37	of	of	ADP
dti-1333	180	38	atherosclerotic	atherosclerotic	ADJ
dti-1333	180	39	plaques	plaque	NOUN
dti-1333	180	40	in	in	ADP
dti-1333	180	41	human	human	ADJ
dti-1333	180	42	patients	patient	NOUN
dti-1333	180	43	.	.	PUNCT
dti-1333	181	1	there	there	PRON
dti-1333	181	2	is	be	VERB
dti-1333	181	3	an	an	DET
dti-1333	181	4	ongoing	ongoing	ADJ
dti-1333	181	5	need	need	NOUN
dti-1333	181	6	for	for	SCONJ
dti-1333	181	7	novel	novel	ADJ
dti-1333	181	8	therapies	therapy	NOUN
dti-1333	181	9	to	to	PART
dti-1333	181	10	increase	increase	VERB
dti-1333	181	11	the	the	DET
dti-1333	181	12	biosynthesis	biosynthesis	NOUN
dti-1333	181	13	of	of	ADP
dti-1333	181	14	hdl	hdl	NOUN
dti-1333	181	15	,	,	PUNCT
dti-1333	181	16	to	to	PART
dti-1333	181	17	inhibit	inhibit	VERB
dti-1333	181	18	the	the	DET
dti-1333	181	19	progression	progression	NOUN
dti-1333	181	20	of	of	ADP
dti-1333	181	21	and	and	CCONJ
dti-1333	181	22	even	even	ADV
dti-1333	181	23	bring	bring	VERB
dti-1333	181	24	about	about	ADP
dti-1333	181	25	regression	regression	NOUN
dti-1333	181	26	of	of	ADP
dti-1333	181	27	atherosclerosis	atherosclerosis	NOUN
dti-1333	181	28	.	.	PUNCT
dti-1333	182	1	the	the	DET
dti-1333	182	2	development	development	NOUN
dti-1333	182	3	of	of	ADP
dti-1333	182	4	a	a	DET
dti-1333	182	5	small	small	ADJ
dti-1333	182	6	molecule	molecule	NOUN
dti-1333	182	7	drug	drug	NOUN
dti-1333	182	8	that	that	PRON
dti-1333	182	9	increased	increase	VERB
dti-1333	182	10	endogenous	endogenous	ADJ
dti-1333	182	11	apoa	apoa	NOUN
dti-1333	182	12	-	-	PUNCT
dti-1333	182	13	i	i	PRON
dti-1333	182	14	would	would	AUX
dti-1333	182	15	be	be	AUX
dti-1333	182	16	a	a	DET
dti-1333	182	17	major	major	ADJ
dti-1333	182	18	advance	advance	NOUN
dti-1333	182	19	in	in	ADP
dti-1333	182	20	treating	treat	VERB
dti-1333	182	21	lipid	lipid	NOUN
dti-1333	182	22	-	-	PUNCT
dti-1333	182	23	related	relate	VERB
dti-1333	182	24	cardiovascular	cardiovascular	ADJ
dti-1333	182	25	disease	disease	NOUN
dti-1333	182	26	.	.	PUNCT
dti-1333	183	1	targeting	target	VERB
dti-1333	183	2	the	the	DET
dti-1333	183	3	patient	patient	NOUN
dti-1333	183	4	’s	’s	PART
dti-1333	183	5	liver	liver	NOUN
dti-1333	183	6	and	and	CCONJ
dti-1333	183	7	small	small	ADJ
dti-1333	183	8	intestine	intestine	NOUN
dti-1333	183	9	to	to	PART
dti-1333	183	10	increase	increase	VERB
dti-1333	183	11	the	the	DET
dti-1333	183	12	transcription	transcription	NOUN
dti-1333	183	13	,	,	PUNCT
dti-1333	183	14	synthesis	synthesis	NOUN
dti-1333	183	15	,	,	PUNCT
dti-1333	183	16	and	and	CCONJ
dti-1333	183	17	secretion	secretion	NOUN
dti-1333	183	18	of	of	ADP
dti-1333	183	19	apoa	apoa	NOUN
dti-1333	183	20	-	-	PUNCT
dti-1333	183	21	i	i	PRON
dti-1333	183	22	is	be	AUX
dti-1333	183	23	generally	generally	ADV
dti-1333	183	24	considered	consider	VERB
dti-1333	183	25	a	a	DET
dti-1333	183	26	promising	promising	ADJ
dti-1333	183	27	approach	approach	NOUN
dti-1333	183	28	for	for	ADP
dti-1333	183	29	raising	raise	VERB
dti-1333	183	30	hdl	hdl	PROPN
dti-1333	183	31	-	-	PUNCT
dti-1333	183	32	c	c	NOUN
dti-1333	183	33	levels	level	NOUN
dti-1333	183	34	.	.	PUNCT
dti-1333	184	1	currently	currently	ADV
dti-1333	184	2	,	,	PUNCT
dti-1333	184	3	our	our	PRON
dti-1333	184	4	ability	ability	NOUN
dti-1333	184	5	to	to	PART
dti-1333	184	6	raise	raise	VERB
dti-1333	184	7	hdl	hdl	PROPN
dti-1333	184	8	is	be	AUX
dti-1333	184	9	limited	limited	ADJ
dti-1333	184	10	;	;	PUNCT
dti-1333	184	11	life	life	NOUN
dti-1333	184	12	style	style	NOUN
dti-1333	184	13	,	,	PUNCT
dti-1333	184	14	including	include	VERB
dti-1333	184	15	dietary	dietary	ADJ
dti-1333	184	16	,	,	PUNCT
dti-1333	184	17	changes	change	NOUN
dti-1333	184	18	,	,	PUNCT
dti-1333	184	19	niacin	niacin	NOUN
dti-1333	184	20	,	,	PUNCT
dti-1333	184	21	fi	fi	NOUN
dti-1333	184	22	brates	brate	NOUN
dti-1333	184	23	,	,	PUNCT
dti-1333	184	24	estrogen	estrogen	NOUN
dti-1333	184	25	,	,	PUNCT
dti-1333	184	26	and	and	CCONJ
dti-1333	184	27	to	to	ADP
dti-1333	184	28	some	some	DET
dti-1333	184	29	degree	degree	NOUN
dti-1333	184	30	,	,	PUNCT
dti-1333	184	31	the	the	DET
dti-1333	184	32	statins	statin	NOUN
dti-1333	184	33	do	do	AUX
dti-1333	184	34	raise	raise	VERB
dti-1333	184	35	hdl	hdl	PROPN
dti-1333	184	36	,	,	PUNCT
dti-1333	184	37	but	but	CCONJ
dti-1333	184	38	not	not	PART
dti-1333	184	39	very	very	ADV
dti-1333	184	40	potently	potently	ADV
dti-1333	184	41	.	.	PUNCT
dti-1333	185	1	several	several	ADJ
dti-1333	185	2	new	new	ADJ
dti-1333	185	3	drug	drug	NOUN
dti-1333	185	4	classes	class	NOUN
dti-1333	185	5	are	be	AUX
dti-1333	185	6	under	under	ADP
dti-1333	185	7	investigation	investigation	NOUN
dti-1333	185	8	in	in	ADP
dti-1333	185	9	this	this	DET
dti-1333	185	10	very	very	ADV
dti-1333	185	11	active	active	ADJ
dti-1333	185	12	fi	fi	NOUN
dti-1333	185	13	eld	eld	NOUN
dti-1333	185	14	.	.	PUNCT
dti-1333	186	1	references	reference	NOUN
dti-1333	186	2	anderson	anderson	PROPN
dti-1333	186	3	,	,	PUNCT
dti-1333	186	4	j.w	j.w	PROPN
dti-1333	186	5	.	.	PROPN
dti-1333	186	6	2003	2003	NUM
dti-1333	186	7	.	.	PUNCT
dti-1333	187	1	whole	whole	ADJ
dti-1333	187	2	grains	grain	NOUN
dti-1333	187	3	protect	protect	VERB
dti-1333	187	4	against	against	ADP
dti-1333	187	5	atherosclerotic	atherosclerotic	ADJ
dti-1333	187	6	cardiovascular	cardiovascular	ADJ
dti-1333	187	7	disease	disease	NOUN
dti-1333	187	8	.	.	PUNCT
dti-1333	188	1	proc	proc	NOUN
dti-1333	188	2	.	.	PUNCT
dti-1333	189	1	nutr	nutr	PROPN
dti-1333	189	2	.	.	PROPN
dti-1333	189	3	soc	soc	PROPN
dti-1333	189	4	.	.	PUNCT
dti-1333	189	5	,	,	PUNCT
dti-1333	189	6	62:135–42	62:135–42	NOUN
dti-1333	189	7	.	.	PUNCT
dti-1333	190	1	ashen	ashen	PROPN
dti-1333	190	2	,	,	PUNCT
dti-1333	190	3	m.d	m.d	PROPN
dti-1333	190	4	.	.	PROPN
dti-1333	190	5	and	and	CCONJ
dti-1333	190	6	blumenthal	blumenthal	PROPN
dti-1333	190	7	,	,	PUNCT
dti-1333	190	8	r.s	r.s	PROPN
dti-1333	190	9	.	.	PROPN
dti-1333	190	10	2005	2005	NUM
dti-1333	190	11	.	.	PUNCT
dti-1333	191	1	clinical	clinical	ADJ
dti-1333	191	2	practice	practice	NOUN
dti-1333	191	3	.	.	PUNCT
dti-1333	192	1	low	low	ADJ
dti-1333	192	2	hdl	hdl	PROPN
dti-1333	192	3	cholesterol	cholesterol	PROPN
dti-1333	192	4	levels	level	NOUN
dti-1333	192	5	.	.	PUNCT
dti-1333	193	1	n.	n.	PROPN
dti-1333	193	2	engl	engl	PROPN
dti-1333	193	3	.	.	PUNCT
dti-1333	194	1	j.	j.	PROPN
dti-1333	194	2	med	med	PROPN
dti-1333	194	3	.	.	PROPN
dti-1333	194	4	,	,	PUNCT
dti-1333	194	5	353:1252–60	353:1252–60	PROPN
dti-1333	194	6	.	.	PROPN
dti-1333	194	7	assmann	assmann	PROPN
dti-1333	194	8	,	,	PUNCT
dti-1333	194	9	g.	g.	PROPN
dti-1333	194	10	,	,	PUNCT
dti-1333	194	11	funke	funke	PROPN
dti-1333	194	12	,	,	PUNCT
dti-1333	194	13	h.	h.	PROPN
dti-1333	194	14	and	and	CCONJ
dti-1333	194	15	schriewer	schriew	ADJ
dti-1333	194	16	,	,	PUNCT
dti-1333	194	17	h.	h.	PROPN
dti-1333	194	18	1982	1982	NUM
dti-1333	194	19	.	.	PUNCT
dti-1333	195	1	the	the	DET
dti-1333	195	2	relationship	relationship	NOUN
dti-1333	195	3	of	of	ADP
dti-1333	195	4	hdl	hdl	NOUN
dti-1333	195	5	-	-	PUNCT
dti-1333	195	6	apolipoprotein	apolipoprotein	VERB
dti-1333	195	7	a	a	PRON
dti-1333	195	8	-	-	PUNCT
dti-1333	195	9	i	i	NOUN
dti-1333	195	10	and	and	CCONJ
dti-1333	195	11	hdl	hdl	PROPN
dti-1333	195	12	-	-	PUNCT
dti-1333	195	13	cholesterol	cholesterol	NOUN
dti-1333	195	14	to	to	PART
dti-1333	195	15	risk	risk	VERB
dti-1333	195	16	factors	factor	NOUN
dti-1333	195	17	of	of	ADP
dti-1333	195	18	coronary	coronary	ADJ
dti-1333	195	19	heart	heart	NOUN
dti-1333	195	20	disease	disease	NOUN
dti-1333	195	21	:	:	PUNCT
dti-1333	195	22	initial	initial	ADJ
dti-1333	195	23	results	result	NOUN
dti-1333	195	24	of	of	ADP
dti-1333	195	25	the	the	DET
dti-1333	195	26	prospective	prospective	ADJ
dti-1333	195	27	epidemiological	epidemiological	ADJ
dti-1333	195	28	study	study	NOUN
dti-1333	195	29	in	in	ADP
dti-1333	195	30	company	company	NOUN
dti-1333	195	31	employees	employee	NOUN
dti-1333	195	32	in	in	ADP
dti-1333	195	33	westfalia	westfalia	PROPN
dti-1333	195	34	.	.	PUNCT
dti-1333	196	1	j.	j.	PROPN
dti-1333	196	2	clin	clin	PROPN
dti-1333	196	3	.	.	PUNCT
dti-1333	197	1	chem	chem	PROPN
dti-1333	197	2	.	.	PUNCT
dti-1333	198	1	clin	clin	PROPN
dti-1333	198	2	.	.	PUNCT
dti-1333	199	1	biochem	biochem	PROPN
dti-1333	199	2	.	.	PUNCT
dti-1333	199	3	,	,	PUNCT
dti-1333	199	4	20:287–9	20:287–9	NUM
dti-1333	199	5	.	.	PUNCT
dti-1333	200	1	barter	barter	NOUN
dti-1333	200	2	,	,	PUNCT
dti-1333	200	3	p.j	p.j	PROPN
dti-1333	200	4	.	.	PROPN
dti-1333	200	5	,	,	PUNCT
dti-1333	200	6	brewer	brewer	PROPN
dti-1333	200	7	,	,	PUNCT
dti-1333	200	8	h.b	h.b	PROPN
dti-1333	200	9	.	.	PROPN
dti-1333	200	10	,	,	PUNCT
dti-1333	200	11	jr	jr	PROPN
dti-1333	200	12	,	,	PUNCT
dti-1333	200	13	chapman	chapman	PROPN
dti-1333	200	14	,	,	PUNCT
dti-1333	200	15	m.j	m.j	PROPN
dti-1333	200	16	.	.	PROPN
dti-1333	200	17	et	et	PROPN
dti-1333	200	18	al	al	PROPN
dti-1333	200	19	.	.	PROPN
dti-1333	200	20	2003	2003	NUM
dti-1333	200	21	.	.	PUNCT
dti-1333	201	1	cholesteryl	cholesteryl	NOUN
dti-1333	201	2	ester	ester	NOUN
dti-1333	201	3	transfer	transfer	NOUN
dti-1333	201	4	protein	protein	NOUN
dti-1333	201	5	:	:	PUNCT
dti-1333	201	6	a	a	DET
dti-1333	201	7	novel	novel	ADJ
dti-1333	201	8	target	target	NOUN
dti-1333	201	9	for	for	ADP
dti-1333	201	10	raising	raise	VERB
dti-1333	201	11	hdl	hdl	NOUN
dti-1333	201	12	and	and	CCONJ
dti-1333	201	13	inhibiting	inhibit	VERB
dti-1333	201	14	atherosclerosis	atherosclerosis	NOUN
dti-1333	201	15	.	.	PUNCT
dti-1333	202	1	arterioscler	arterioscler	NOUN
dti-1333	202	2	.	.	PUNCT
dti-1333	203	1	thromb	thromb	PROPN
dti-1333	203	2	.	.	PUNCT
dti-1333	204	1	vasc	vasc	PROPN
dti-1333	204	2	.	.	PUNCT
dti-1333	205	1	biol	biol	PROPN
dti-1333	205	2	.	.	PUNCT
dti-1333	205	3	,	,	PUNCT
dti-1333	206	1	23:160–7	23:160–7	X
dti-1333	206	2	.	.	PUNCT
dti-1333	207	1	barter	barter	NOUN
dti-1333	207	2	,	,	PUNCT
dti-1333	207	3	p.j	p.j	PROPN
dti-1333	207	4	.	.	PROPN
dti-1333	207	5	,	,	PUNCT
dti-1333	207	6	caulfi	caulfi	PROPN
dti-1333	207	7	eld	eld	PROPN
dti-1333	207	8	,	,	PUNCT
dti-1333	207	9	m.	m.	NOUN
dti-1333	207	10	,	,	PUNCT
dti-1333	207	11	eriksson	eriksson	PROPN
dti-1333	207	12	,	,	PUNCT
dti-1333	207	13	m.	m.	NOUN
dti-1333	207	14	et	et	PROPN
dti-1333	207	15	al	al	PROPN
dti-1333	207	16	.	.	PROPN
dti-1333	207	17	2007	2007	NUM
dti-1333	207	18	.	.	PUNCT
dti-1333	208	1	effects	effect	NOUN
dti-1333	208	2	of	of	ADP
dti-1333	208	3	torcetrapib	torcetrapib	ADJ
dti-1333	208	4	in	in	ADP
dti-1333	208	5	patients	patient	NOUN
dti-1333	208	6	at	at	ADP
dti-1333	208	7	high	high	ADJ
dti-1333	208	8	risk	risk	NOUN
dti-1333	208	9	for	for	ADP
dti-1333	208	10	coronary	coronary	ADJ
dti-1333	208	11	events	event	NOUN
dti-1333	208	12	.	.	PUNCT
dti-1333	209	1	new	new	ADJ
dti-1333	209	2	engl	engl	PROPN
dti-1333	209	3	.	.	PUNCT
dti-1333	210	1	j.	j.	PROPN
dti-1333	210	2	med	med	PROPN
dti-1333	210	3	.	.	PROPN
dti-1333	210	4	,	,	PUNCT
dti-1333	210	5	357:2109–22	357:2109–22	NUM
dti-1333	210	6	.	.	PUNCT
dti-1333	211	1	barter	barter	NOUN
dti-1333	211	2	,	,	PUNCT
dti-1333	211	3	p.j	p.j	PROPN
dti-1333	211	4	.	.	PROPN
dti-1333	211	5	and	and	CCONJ
dti-1333	211	6	kastelein	kastelein	PROPN
dti-1333	211	7	,	,	PUNCT
dti-1333	211	8	j.j	j.j	PROPN
dti-1333	211	9	.	.	PROPN
dti-1333	211	10	2006	2006	NUM
dti-1333	211	11	.	.	PUNCT
dti-1333	212	1	targeting	target	VERB
dti-1333	212	2	cholesteryl	cholesteryl	NOUN
dti-1333	212	3	ester	ester	NOUN
dti-1333	212	4	transfer	transfer	NOUN
dti-1333	212	5	protein	protein	NOUN
dti-1333	212	6	for	for	ADP
dti-1333	212	7	the	the	DET
dti-1333	212	8	prevention	prevention	NOUN
dti-1333	212	9	and	and	CCONJ
dti-1333	212	10	management	management	NOUN
dti-1333	212	11	of	of	ADP
dti-1333	212	12	cardiovascular	cardiovascular	ADJ
dti-1333	212	13	disease	disease	NOUN
dti-1333	212	14	.	.	PUNCT
dti-1333	213	1	j.	j.	PROPN
dti-1333	213	2	am	am	PROPN
dti-1333	213	3	.	.	PUNCT
dti-1333	214	1	coll	coll	PROPN
dti-1333	214	2	.	.	PUNCT
dti-1333	215	1	cardiol	cardiol	PROPN
dti-1333	215	2	.	.	PUNCT
dti-1333	215	3	,	,	PUNCT
dti-1333	215	4	47:492–9	47:492–9	NUM
dti-1333	215	5	.	.	PUNCT
dti-1333	215	6	birjmohun	birjmohun	PROPN
dti-1333	215	7	,	,	PUNCT
dti-1333	215	8	r.s	r.s	PROPN
dti-1333	215	9	.	.	PROPN
dti-1333	215	10	,	,	PUNCT
dti-1333	215	11	hutten	hutten	PROPN
dti-1333	215	12	,	,	PUNCT
dti-1333	215	13	b.a	b.a	PROPN
dti-1333	215	14	.	.	PROPN
dti-1333	215	15	,	,	PUNCT
dti-1333	215	16	kastelein	kastelein	PROPN
dti-1333	215	17	,	,	PUNCT
dti-1333	215	18	j.j	j.j	PROPN
dti-1333	215	19	.	.	PROPN
dti-1333	215	20	et	et	PROPN
dti-1333	215	21	al	al	PROPN
dti-1333	215	22	.	.	PROPN
dti-1333	215	23	2004	2004	NUM
dti-1333	215	24	.	.	PUNCT
dti-1333	216	1	increasing	increase	VERB
dti-1333	216	2	hdl	hdl	PROPN
dti-1333	216	3	cholesterol	cholesterol	NOUN
dti-1333	216	4	with	with	ADP
dti-1333	216	5	extended	extend	VERB
dti-1333	216	6	-	-	PUNCT
dti-1333	216	7	release	release	NOUN
dti-1333	216	8	nicotinic	nicotinic	ADJ
dti-1333	216	9	acid	acid	NOUN
dti-1333	216	10	:	:	PUNCT
dti-1333	216	11	from	from	ADP
dti-1333	216	12	promise	promise	NOUN
dti-1333	216	13	to	to	PART
dti-1333	216	14	practice	practice	VERB
dti-1333	216	15	.	.	PUNCT
dti-1333	217	1	neth	neth	PROPN
dti-1333	217	2	.	.	PUNCT
dti-1333	218	1	j.	j.	PROPN
dti-1333	218	2	med	med	PROPN
dti-1333	218	3	.	.	PROPN
dti-1333	218	4	,	,	PUNCT
dti-1333	218	5	62:229–34	62:229–34	NOUN
dti-1333	218	6	.	.	PUNCT
dti-1333	219	1	boden	boden	PROPN
dti-1333	219	2	,	,	PUNCT
dti-1333	219	3	w.e	w.e	PROPN
dti-1333	219	4	.	.	PROPN
dti-1333	219	5	2000	2000	NUM
dti-1333	219	6	.	.	PUNCT
dti-1333	220	1	high	high	ADJ
dti-1333	220	2	-	-	PUNCT
dti-1333	220	3	density	density	NOUN
dti-1333	220	4	lipoprotein	lipoprotein	ADJ
dti-1333	220	5	cholesterol	cholesterol	NOUN
dti-1333	220	6	as	as	ADP
dti-1333	220	7	an	an	DET
dti-1333	220	8	independent	independent	ADJ
dti-1333	220	9	risk	risk	NOUN
dti-1333	220	10	factor	factor	NOUN
dti-1333	220	11	in	in	ADP
dti-1333	220	12	cardiovascular	cardiovascular	ADJ
dti-1333	220	13	disease	disease	NOUN
dti-1333	220	14	:	:	PUNCT
dti-1333	220	15	assessing	assess	VERB
dti-1333	220	16	the	the	DET
dti-1333	220	17	data	datum	NOUN
dti-1333	220	18	from	from	ADP
dti-1333	220	19	framingham	framingham	PROPN
dti-1333	220	20	to	to	ADP
dti-1333	220	21	the	the	DET
dti-1333	220	22	veterans	veterans	PROPN
dti-1333	220	23	affairs	affair	VERB
dti-1333	220	24	high	high	ADJ
dti-1333	220	25	-	-	PUNCT
dti-1333	220	26	density	density	NOUN
dti-1333	220	27	lipoprotein	lipoprotein	ADJ
dti-1333	220	28	intervention	intervention	NOUN
dti-1333	220	29	trial	trial	NOUN
dti-1333	220	30	.	.	PUNCT
dti-1333	221	1	am	be	AUX
dti-1333	221	2	.	.	PUNCT
dti-1333	222	1	j.	j.	PROPN
dti-1333	222	2	cardiol	cardiol	PROPN
dti-1333	222	3	.	.	PUNCT
dti-1333	222	4	,	,	PUNCT
dti-1333	222	5	86:19l–22l	86:19l–22l	PROPN
dti-1333	222	6	.	.	PUNCT
dti-1333	222	7	bonn	bonn	PROPN
dti-1333	222	8	,	,	PUNCT
dti-1333	222	9	v.	v.	PROPN
dti-1333	222	10	,	,	PUNCT
dti-1333	222	11	cheung	cheung	PROPN
dti-1333	222	12	,	,	PUNCT
dti-1333	222	13	r.c	r.c	PROPN
dti-1333	222	14	.	.	PROPN
dti-1333	222	15	,	,	PUNCT
dti-1333	222	16	chen	chen	PROPN
dti-1333	222	17	,	,	PUNCT
dti-1333	222	18	b.	b.	PROPN
dti-1333	222	19	et	et	PROPN
dti-1333	222	20	al	al	PROPN
dti-1333	222	21	.	.	PROPN
dti-1333	222	22	2002	2002	NUM
dti-1333	222	23	.	.	PUNCT
dti-1333	223	1	simvastatin	simvastatin	PROPN
dti-1333	223	2	,	,	PUNCT
dti-1333	223	3	an	an	DET
dti-1333	223	4	hmg	hmg	NOUN
dti-1333	223	5	-	-	PUNCT
dti-1333	223	6	coa	coa	NOUN
dti-1333	223	7	reductase	reductase	NOUN
dti-1333	223	8	inhibitor	inhibitor	NOUN
dti-1333	223	9	,	,	PUNCT
dti-1333	223	10	induces	induce	VERB
dti-1333	223	11	the	the	DET
dti-1333	223	12	synthesis	synthesis	NOUN
dti-1333	223	13	and	and	CCONJ
dti-1333	223	14	secretion	secretion	NOUN
dti-1333	223	15	of	of	ADP
dti-1333	223	16	apolipoprotein	apolipoprotein	ADJ
dti-1333	223	17	ai	ai	VERB
dti-1333	223	18	in	in	ADP
dti-1333	223	19	hepg2	hepg2	NOUN
dti-1333	223	20	cells	cell	NOUN
dti-1333	223	21	and	and	CCONJ
dti-1333	223	22	primary	primary	ADJ
dti-1333	223	23	hamster	hamster	NOUN
dti-1333	223	24	hepatocytes	hepatocyte	VERB
dti-1333	223	25	.	.	PUNCT
dti-1333	224	1	atherosclerosis	atherosclerosis	NOUN
dti-1333	224	2	,	,	PUNCT
dti-1333	224	3	163:59–68	163:59–68	X
dti-1333	224	4	.	.	PUNCT
dti-1333	224	5	brunham	brunham	PROPN
dti-1333	224	6	,	,	PUNCT
dti-1333	224	7	l.r	l.r	PROPN
dti-1333	224	8	.	.	PROPN
dti-1333	224	9	,	,	PUNCT
dti-1333	224	10	singaraja	singaraja	PROPN
dti-1333	224	11	,	,	PUNCT
dti-1333	224	12	r.r	r.r	PROPN
dti-1333	224	13	.	.	PROPN
dti-1333	224	14	and	and	CCONJ
dti-1333	224	15	hayden	hayden	PROPN
dti-1333	224	16	,	,	PUNCT
dti-1333	224	17	m.r	m.r	PROPN
dti-1333	224	18	.	.	PROPN
dti-1333	224	19	2006	2006	NUM
dti-1333	224	20	.	.	PUNCT
dti-1333	225	1	variations	variation	NOUN
dti-1333	225	2	on	on	ADP
dti-1333	225	3	a	a	DET
dti-1333	225	4	gene	gene	NOUN
dti-1333	225	5	:	:	PUNCT
dti-1333	225	6	rare	rare	ADJ
dti-1333	225	7	and	and	CCONJ
dti-1333	225	8	common	common	ADJ
dti-1333	225	9	variants	variant	NOUN
dti-1333	225	10	in	in	ADP
dti-1333	225	11	abca1	abca1	NOUN
dti-1333	225	12	and	and	CCONJ
dti-1333	225	13	their	their	PRON
dti-1333	225	14	impact	impact	NOUN
dti-1333	225	15	on	on	ADP
dti-1333	225	16	hdl	hdl	PROPN
dti-1333	225	17	cholesterol	cholesterol	PROPN
dti-1333	225	18	levels	level	NOUN
dti-1333	225	19	and	and	CCONJ
dti-1333	225	20	atherosclerosis	atherosclerosis	NOUN
dti-1333	225	21	.	.	PUNCT
dti-1333	226	1	annu	annu	NOUN
dti-1333	226	2	.	.	PUNCT
dti-1333	226	3	rev	rev	PROPN
dti-1333	226	4	.	.	PROPN
dti-1333	226	5	nutr	nutr	PROPN
dti-1333	226	6	.	.	PROPN
dti-1333	226	7	,	,	PUNCT
dti-1333	226	8	26:105–29	26:105–29	NOUN
dti-1333	226	9	.	.	PUNCT
dti-1333	227	1	burgess	burgess	PROPN
dti-1333	227	2	,	,	PUNCT
dti-1333	227	3	j.w	j.w	PROPN
dti-1333	227	4	.	.	PROPN
dti-1333	227	5	,	,	PUNCT
dti-1333	227	6	neville	neville	PROPN
dti-1333	227	7	,	,	PUNCT
dti-1333	227	8	t.a	t.a	PROPN
dti-1333	227	9	.	.	PROPN
dti-1333	227	10	,	,	PUNCT
dti-1333	227	11	rouillard	rouillard	PROPN
dti-1333	227	12	,	,	PUNCT
dti-1333	227	13	p.	p.	NOUN
dti-1333	227	14	et	et	NOUN
dti-1333	228	1	al	al	PROPN
dti-1333	228	2	.	.	PROPN
dti-1333	228	3	2005	2005	NUM
dti-1333	228	4	.	.	PUNCT
dti-1333	229	1	phosphatidylinositol	phosphatidylinositol	NOUN
dti-1333	229	2	increases	increase	VERB
dti-1333	229	3	hdl	hdl	PROPN
dti-1333	229	4	-	-	PUNCT
dti-1333	229	5	c	c	PROPN
dti-1333	229	6	levels	level	NOUN
dti-1333	229	7	in	in	ADP
dti-1333	229	8	humans	human	NOUN
dti-1333	229	9	.	.	PUNCT
dti-1333	230	1	j.	j.	PROPN
dti-1333	230	2	lipid	lipid	PROPN
dti-1333	230	3	res	res	PROPN
dti-1333	230	4	.	.	PROPN
dti-1333	230	5	,	,	PUNCT
dti-1333	230	6	46:350–5	46:350–5	NUM
dti-1333	230	7	.	.	PUNCT
dti-1333	231	1	burr	burr	PROPN
dti-1333	231	2	,	,	PUNCT
dti-1333	231	3	m.l	m.l	PROPN
dti-1333	231	4	.	.	PROPN
dti-1333	231	5	1995	1995	NUM
dti-1333	231	6	.	.	PUNCT
dti-1333	232	1	explaining	explain	VERB
dti-1333	232	2	the	the	DET
dti-1333	232	3	french	french	ADJ
dti-1333	232	4	paradox	paradox	NOUN
dti-1333	232	5	.	.	PUNCT
dti-1333	233	1	j.	j.	PROPN
dti-1333	233	2	r.	r.	PROPN
dti-1333	233	3	soc	soc	PROPN
dti-1333	233	4	.	.	PUNCT
dti-1333	234	1	health	health	NOUN
dti-1333	234	2	,	,	PUNCT
dti-1333	234	3	115:217–9	115:217–9	NUM
dti-1333	234	4	.	.	PUNCT
dti-1333	235	1	calabresi	calabresi	PROPN
dti-1333	235	2	,	,	PUNCT
dti-1333	235	3	l.	l.	PROPN
dti-1333	235	4	and	and	CCONJ
dti-1333	235	5	franceschini	franceschini	PROPN
dti-1333	235	6	,	,	PUNCT
dti-1333	235	7	g.	g.	PROPN
dti-1333	235	8	1997	1997	NUM
dti-1333	235	9	.	.	PUNCT
dti-1333	236	1	high	high	ADJ
dti-1333	236	2	density	density	NOUN
dti-1333	236	3	lipoprotein	lipoprotein	ADJ
dti-1333	236	4	and	and	CCONJ
dti-1333	236	5	coronary	coronary	ADJ
dti-1333	236	6	heart	heart	NOUN
dti-1333	236	7	disease	disease	NOUN
dti-1333	236	8	:	:	PUNCT
dti-1333	236	9	insights	insight	NOUN
dti-1333	236	10	from	from	ADP
dti-1333	236	11	mutations	mutation	NOUN
dti-1333	236	12	leading	lead	VERB
dti-1333	236	13	to	to	ADP
dti-1333	236	14	low	low	ADJ
dti-1333	236	15	high	high	ADJ
dti-1333	236	16	density	density	NOUN
dti-1333	236	17	lipoprotein	lipoprotein	ADJ
dti-1333	236	18	.	.	PUNCT
dti-1333	237	1	curr	curr	PROPN
dti-1333	237	2	.	.	PUNCT
dti-1333	238	1	opin	opin	NOUN
dti-1333	238	2	.	.	PUNCT
dti-1333	239	1	lipidol	lipidol	PROPN
dti-1333	239	2	.	.	PUNCT
dti-1333	240	1	,	,	PUNCT
dti-1333	240	2	8:219–24	8:219–24	PROPN
dti-1333	240	3	.	.	PUNCT
dti-1333	241	1	chapman	chapman	PROPN
dti-1333	241	2	,	,	PUNCT
dti-1333	241	3	m.j	m.j	PROPN
dti-1333	241	4	.	.	PROPN
dti-1333	241	5	2005	2005	NUM
dti-1333	241	6	.	.	PUNCT
dti-1333	242	1	beyond	beyond	ADP
dti-1333	242	2	the	the	DET
dti-1333	242	3	statins	statin	NOUN
dti-1333	242	4	:	:	PUNCT
dti-1333	242	5	new	new	ADJ
dti-1333	242	6	therapeutic	therapeutic	ADJ
dti-1333	242	7	perspectives	perspective	NOUN
dti-1333	242	8	in	in	ADP
dti-1333	242	9	cardiovascular	cardiovascular	ADJ
dti-1333	242	10	disease	disease	NOUN
dti-1333	242	11	prevention	prevention	NOUN
dti-1333	242	12	.	.	PUNCT
dti-1333	243	1	cardiovasc	cardiovasc	PROPN
dti-1333	243	2	.	.	PUNCT
dti-1333	244	1	drugs	drug	NOUN
dti-1333	244	2	ther	ther	ADV
dti-1333	244	3	.	.	PUNCT
dti-1333	244	4	,	,	PUNCT
dti-1333	244	5	19:135–9	19:135–9	NUM
dti-1333	244	6	.	.	PUNCT
dti-1333	245	1	doggrell	doggrell	NOUN
dti-1333	245	2	,	,	PUNCT
dti-1333	245	3	s.a	s.a	PROPN
dti-1333	245	4	.	.	PROPN
dti-1333	245	5	2004	2004	NUM
dti-1333	245	6	.	.	PUNCT
dti-1333	246	1	raising	raise	VERB
dti-1333	246	2	high	high	ADJ
dti-1333	246	3	-	-	PUNCT
dti-1333	246	4	density	density	NOUN
dti-1333	246	5	lipoprotein	lipoprotein	ADJ
dti-1333	246	6	cholesterol	cholesterol	NOUN
dti-1333	246	7	with	with	ADP
dti-1333	246	8	inhibitors	inhibitor	NOUN
dti-1333	246	9	of	of	ADP
dti-1333	246	10	cholesteryl	cholesteryl	NOUN
dti-1333	246	11	ester	ester	NOUN
dti-1333	246	12	transfer	transfer	NOUN
dti-1333	246	13	protein	protein	NOUN
dti-1333	246	14	—	—	PUNCT
dti-1333	246	15	a	a	DET
dti-1333	246	16	new	new	ADJ
dti-1333	246	17	approach	approach	NOUN
dti-1333	246	18	to	to	ADP
dti-1333	246	19	coronary	coronary	ADJ
dti-1333	246	20	artery	artery	NOUN
dti-1333	246	21	disease	disease	NOUN
dti-1333	246	22	.	.	PUNCT
dti-1333	247	1	expert	expert	NOUN
dti-1333	247	2	opin	opin	NOUN
dti-1333	247	3	.	.	PUNCT
dti-1333	248	1	investig	investig	PROPN
dti-1333	248	2	.	.	PUNCT
dti-1333	249	1	drugs	drug	NOUN
dti-1333	249	2	,	,	PUNCT
dti-1333	249	3	13:1365–8	13:1365–8	NUM
dti-1333	249	4	.	.	PUNCT
dti-1333	250	1	downs	down	NOUN
dti-1333	250	2	,	,	PUNCT
dti-1333	250	3	j.r	j.r	PROPN
dti-1333	250	4	.	.	PROPN
dti-1333	250	5	,	,	PUNCT
dti-1333	250	6	clearfi	clearfi	PROPN
dti-1333	250	7	eld	eld	NOUN
dti-1333	250	8	,	,	PUNCT
dti-1333	250	9	m.	m.	NOUN
dti-1333	250	10	,	,	PUNCT
dti-1333	250	11	weis	weis	PROPN
dti-1333	250	12	,	,	PUNCT
dti-1333	250	13	s.	s.	PROPN
dti-1333	250	14	et	et	PROPN
dti-1333	250	15	al	al	PROPN
dti-1333	250	16	.	.	PROPN
dti-1333	250	17	1998	1998	NUM
dti-1333	250	18	.	.	PUNCT
dti-1333	251	1	primary	primary	ADJ
dti-1333	251	2	prevention	prevention	NOUN
dti-1333	251	3	of	of	ADP
dti-1333	251	4	acute	acute	ADJ
dti-1333	251	5	coronary	coronary	ADJ
dti-1333	251	6	events	event	NOUN
dti-1333	251	7	with	with	ADP
dti-1333	251	8	lovastatin	lovastatin	NOUN
dti-1333	251	9	in	in	ADP
dti-1333	251	10	men	man	NOUN
dti-1333	251	11	and	and	CCONJ
dti-1333	251	12	women	woman	NOUN
dti-1333	251	13	with	with	ADP
dti-1333	251	14	average	average	ADJ
dti-1333	251	15	cholesterol	cholesterol	NOUN
dti-1333	251	16	levels	level	NOUN
dti-1333	251	17	:	:	PUNCT
dti-1333	251	18	results	result	NOUN
dti-1333	251	19	of	of	ADP
dti-1333	251	20	afcaps	afcap	NOUN
dti-1333	251	21	/	/	SYM
dti-1333	251	22	texcaps	texcap	NOUN
dti-1333	251	23	.	.	PUNCT
dti-1333	252	1	air	air	PROPN
dti-1333	252	2	force	force	PROPN
dti-1333	252	3	/	/	SYM
dti-1333	252	4	texas	texas	PROPN
dti-1333	252	5	coronary	coronary	ADJ
dti-1333	252	6	atherosclerosis	atherosclerosis	NOUN
dti-1333	252	7	prevention	prevention	NOUN
dti-1333	252	8	study	study	NOUN
dti-1333	252	9	.	.	PUNCT
dti-1333	253	1	jama	jama	PROPN
dti-1333	253	2	,	,	PUNCT
dti-1333	253	3	279:1615–22	279:1615–22	PROPN
dti-1333	253	4	.	.	PUNCT
dti-1333	253	5	eriksson	eriksson	PROPN
dti-1333	253	6	,	,	PUNCT
dti-1333	253	7	m.	m.	NOUN
dti-1333	253	8	,	,	PUNCT
dti-1333	253	9	carlson	carlson	PROPN
dti-1333	253	10	,	,	PUNCT
dti-1333	253	11	l.a	l.a	PROPN
dti-1333	253	12	.	.	PROPN
dti-1333	253	13	,	,	PUNCT
dti-1333	253	14	miettinen	miettinen	PROPN
dti-1333	253	15	,	,	PUNCT
dti-1333	253	16	t.a	t.a	PROPN
dti-1333	253	17	.	.	PROPN
dti-1333	253	18	et	et	PROPN
dti-1333	253	19	al	al	PROPN
dti-1333	253	20	.	.	PROPN
dti-1333	253	21	1999	1999	NUM
dti-1333	253	22	.	.	PUNCT
dti-1333	254	1	stimulation	stimulation	NOUN
dti-1333	254	2	of	of	ADP
dti-1333	254	3	fecal	fecal	ADJ
dti-1333	254	4	steroid	steroid	NOUN
dti-1333	254	5	excretion	excretion	NOUN
dti-1333	254	6	after	after	ADP
dti-1333	254	7	infusion	infusion	NOUN
dti-1333	254	8	of	of	ADP
dti-1333	254	9	recombinant	recombinant	ADJ
dti-1333	254	10	proapolipoprotein	proapolipoprotein	NOUN
dti-1333	254	11	a	a	DET
dti-1333	254	12	-	-	PUNCT
dti-1333	254	13	i.	i.	NOUN
dti-1333	254	14	potential	potential	ADJ
dti-1333	254	15	reverse	reverse	ADJ
dti-1333	254	16	cholesterol	cholesterol	NOUN
dti-1333	254	17	transport	transport	NOUN
dti-1333	254	18	in	in	ADP
dti-1333	254	19	humans	human	NOUN
dti-1333	254	20	.	.	PUNCT
dti-1333	255	1	circulation	circulation	NOUN
dti-1333	255	2	,	,	PUNCT
dti-1333	255	3	100:594–8	100:594–8	NUM
dti-1333	255	4	.	.	PUNCT
dti-1333	255	5	frohlich	frohlich	PROPN
dti-1333	255	6	,	,	PUNCT
dti-1333	255	7	j.	j.	PROPN
dti-1333	255	8	,	,	PUNCT
dti-1333	255	9	westerlund	westerlund	PROPN
dti-1333	255	10	,	,	PUNCT
dti-1333	255	11	j.	j.	PROPN
dti-1333	255	12	,	,	PUNCT
dti-1333	255	13	sparks	spark	VERB
dti-1333	255	14	,	,	PUNCT
dti-1333	255	15	d.	d.	PROPN
dti-1333	255	16	et	et	PROPN
dti-1333	255	17	al	al	PROPN
dti-1333	255	18	.	.	PROPN
dti-1333	255	19	1990	1990	NUM
dti-1333	255	20	.	.	PUNCT
dti-1333	256	1	familial	familial	ADJ
dti-1333	256	2	hypoalphalipoproteinemias	hypoalphalipoproteinemia	NOUN
dti-1333	256	3	.	.	PUNCT
dti-1333	257	1	clin	clin	PROPN
dti-1333	257	2	.	.	PUNCT
dti-1333	258	1	invest	invest	PROPN
dti-1333	258	2	.	.	PUNCT
dti-1333	259	1	med	med	PROPN
dti-1333	259	2	.	.	PROPN
dti-1333	259	3	,	,	PUNCT
dti-1333	259	4	13:202–10	13:202–10	NUM
dti-1333	259	5	.	.	PUNCT
dti-1333	260	1	forrester	forrester	PROPN
dti-1333	260	2	,	,	PUNCT
dti-1333	260	3	j.s	j.s	PROPN
dti-1333	260	4	.	.	PROPN
dti-1333	260	5	,	,	PUNCT
dti-1333	260	6	makkar	makkar	PROPN
dti-1333	260	7	,	,	PUNCT
dti-1333	260	8	r.	r.	PROPN
dti-1333	260	9	and	and	CCONJ
dti-1333	260	10	shah	shah	PROPN
dti-1333	260	11	,	,	PUNCT
dti-1333	260	12	p.k	p.k	PROPN
dti-1333	260	13	.	.	PROPN
dti-1333	260	14	2005	2005	NUM
dti-1333	260	15	.	.	PUNCT
dti-1333	261	1	increasing	increase	VERB
dti-1333	261	2	high	high	ADJ
dti-1333	261	3	-	-	PUNCT
dti-1333	261	4	density	density	NOUN
dti-1333	261	5	lipoprotein	lipoprotein	ADJ
dti-1333	261	6	cholesterol	cholesterol	NOUN
dti-1333	261	7	in	in	ADP
dti-1333	261	8	dyslipidemia	dyslipidemia	NOUN
dti-1333	261	9	by	by	ADP
dti-1333	261	10	cholesteryl	cholesteryl	NOUN
dti-1333	261	11	ester	ester	NOUN
dti-1333	261	12	transfer	transfer	NOUN
dti-1333	261	13	protein	protein	NOUN
dti-1333	261	14	inhibition	inhibition	NOUN
dti-1333	261	15	:	:	PUNCT
dti-1333	261	16	an	an	DET
dti-1333	261	17	update	update	NOUN
dti-1333	261	18	for	for	ADP
dti-1333	261	19	clinicians	clinician	NOUN
dti-1333	261	20	.	.	PUNCT
dti-1333	262	1	circulation	circulation	NOUN
dti-1333	262	2	,	,	PUNCT
dti-1333	262	3	111:1847–54	111:1847–54	NUM
dti-1333	262	4	.	.	PUNCT
dti-1333	263	1	forrester	forrester	PROPN
dti-1333	263	2	,	,	PUNCT
dti-1333	263	3	j.s	j.s	PROPN
dti-1333	263	4	.	.	PROPN
dti-1333	263	5	and	and	CCONJ
dti-1333	263	6	shah	shah	PROPN
dti-1333	263	7	,	,	PUNCT
dti-1333	263	8	p.k	p.k	PROPN
dti-1333	263	9	.	.	PROPN
dti-1333	263	10	2006	2006	NUM
dti-1333	263	11	.	.	PUNCT
dti-1333	264	1	emerging	emerge	VERB
dti-1333	264	2	strategies	strategy	NOUN
dti-1333	264	3	for	for	ADP
dti-1333	264	4	increasing	increase	VERB
dti-1333	264	5	high	high	ADJ
dti-1333	264	6	-	-	PUNCT
dti-1333	264	7	density	density	NOUN
dti-1333	264	8	lipoprotein	lipoprotein	NOUN
dti-1333	264	9	.	.	PUNCT
dti-1333	265	1	am	be	AUX
dti-1333	265	2	.	.	PUNCT
dti-1333	266	1	j.	j.	PROPN
dti-1333	266	2	cardiol	cardiol	PROPN
dti-1333	266	3	.	.	PUNCT
dti-1333	266	4	,	,	PUNCT
dti-1333	266	5	98:1542–9	98:1542–9	X
dti-1333	266	6	.	.	PUNCT
dti-1333	266	7	fruchart	fruchart	PROPN
dti-1333	266	8	,	,	PUNCT
dti-1333	266	9	j.c	j.c	PROPN
dti-1333	266	10	.	.	PROPN
dti-1333	266	11	and	and	CCONJ
dti-1333	266	12	duriez	duriez	NOUN
dti-1333	266	13	,	,	PUNCT
dti-1333	266	14	p.	p.	NOUN
dti-1333	266	15	2006	2006	NUM
dti-1333	266	16	.	.	PUNCT
dti-1333	267	1	mode	mode	NOUN
dti-1333	267	2	of	of	ADP
dti-1333	267	3	action	action	NOUN
dti-1333	267	4	of	of	ADP
dti-1333	267	5	fi	fi	NOUN
dti-1333	267	6	brates	brate	NOUN
dti-1333	267	7	in	in	ADP
dti-1333	267	8	the	the	DET
dti-1333	267	9	regulation	regulation	NOUN
dti-1333	267	10	of	of	ADP
dti-1333	267	11	triglyceride	triglyceride	ADJ
dti-1333	267	12	and	and	CCONJ
dti-1333	267	13	hdl	hdl	NOUN
dti-1333	267	14	-	-	PUNCT
dti-1333	267	15	cholesterol	cholesterol	NOUN
dti-1333	267	16	metabolism	metabolism	NOUN
dti-1333	267	17	.	.	PUNCT
dti-1333	268	1	drugs	drug	NOUN
dti-1333	268	2	today	today	NOUN
dti-1333	268	3	,	,	PUNCT
dti-1333	268	4	42:39–64	42:39–64	PROPN
dti-1333	268	5	.	.	PUNCT
dti-1333	269	1	gordon	gordon	PROPN
dti-1333	269	2	,	,	PUNCT
dti-1333	269	3	t.	t.	PROPN
dti-1333	269	4	,	,	PUNCT
dti-1333	269	5	castelli	castelli	PROPN
dti-1333	269	6	,	,	PUNCT
dti-1333	269	7	w.p	w.p	PROPN
dti-1333	269	8	.	.	PROPN
dti-1333	269	9	,	,	PUNCT
dti-1333	269	10	hjortland	hjortland	PROPN
dti-1333	269	11	,	,	PUNCT
dti-1333	269	12	m.c	m.c	PROPN
dti-1333	269	13	.	.	PROPN
dti-1333	269	14	et	et	PROPN
dti-1333	269	15	al	al	PROPN
dti-1333	269	16	.	.	PROPN
dti-1333	269	17	1977	1977	NUM
dti-1333	269	18	.	.	PUNCT
dti-1333	270	1	high	high	ADJ
dti-1333	270	2	density	density	NOUN
dti-1333	270	3	lipoprotein	lipoprotein	ADJ
dti-1333	270	4	as	as	ADP
dti-1333	270	5	a	a	DET
dti-1333	270	6	protective	protective	ADJ
dti-1333	270	7	factor	factor	NOUN
dti-1333	270	8	against	against	ADP
dti-1333	270	9	coronary	coronary	ADJ
dti-1333	270	10	heart	heart	NOUN
dti-1333	270	11	disease	disease	NOUN
dti-1333	270	12	.	.	PUNCT
dti-1333	271	1	the	the	DET
dti-1333	271	2	framingham	framingham	PROPN
dti-1333	271	3	study	study	PROPN
dti-1333	271	4	.	.	PUNCT
dti-1333	272	1	am	be	AUX
dti-1333	272	2	.	.	PUNCT
dti-1333	273	1	j.	j.	PROPN
dti-1333	273	2	med	med	PROPN
dti-1333	273	3	.	.	PROPN
dti-1333	273	4	,	,	PUNCT
dti-1333	273	5	62:707–14	62:707–14	PROPN
dti-1333	273	6	.	.	PUNCT
dti-1333	274	1	hermansen	hermansen	PROPN
dti-1333	274	2	,	,	PUNCT
dti-1333	274	3	k.	k.	PROPN
dti-1333	274	4	,	,	PUNCT
dti-1333	274	5	dinesen	dinesen	PROPN
dti-1333	274	6	,	,	PUNCT
dti-1333	274	7	b.	b.	PROPN
dti-1333	274	8	,	,	PUNCT
dti-1333	274	9	hoie	hoie	NOUN
dti-1333	274	10	,	,	PUNCT
dti-1333	274	11	l.h	l.h	PROPN
dti-1333	274	12	.	.	PROPN
dti-1333	274	13	et	et	PROPN
dti-1333	274	14	al	al	PROPN
dti-1333	274	15	.	.	PROPN
dti-1333	274	16	2003	2003	NUM
dti-1333	274	17	.	.	PUNCT
dti-1333	275	1	effects	effect	NOUN
dti-1333	275	2	of	of	ADP
dti-1333	275	3	soy	soy	NOUN
dti-1333	275	4	and	and	CCONJ
dti-1333	275	5	other	other	ADJ
dti-1333	275	6	natural	natural	ADJ
dti-1333	275	7	products	product	NOUN
dti-1333	275	8	on	on	ADP
dti-1333	275	9	ldl	ldl	NOUN
dti-1333	275	10	:	:	PUNCT
dti-1333	275	11	hdl	hdl	PROPN
dti-1333	275	12	ratio	ratio	NOUN
dti-1333	275	13	and	and	CCONJ
dti-1333	275	14	other	other	ADJ
dti-1333	275	15	lipid	lipid	NOUN
dti-1333	275	16	parameters	parameter	NOUN
dti-1333	275	17	:	:	PUNCT
dti-1333	275	18	a	a	DET
dti-1333	275	19	literature	literature	NOUN
dti-1333	275	20	review	review	NOUN
dti-1333	275	21	.	.	PUNCT
dti-1333	276	1	adv	adv	INTJ
dti-1333	276	2	.	.	PUNCT
dti-1333	277	1	there	there	ADV
dti-1333	277	2	,	,	PUNCT
dti-1333	277	3	20:50–78	20:50–78	NUM
dti-1333	277	4	.	.	PUNCT
dti-1333	278	1	hovingh	hovingh	PROPN
dti-1333	278	2	,	,	PUNCT
dti-1333	278	3	g.k	g.k	PROPN
dti-1333	278	4	.	.	PROPN
dti-1333	278	5	,	,	PUNCT
dti-1333	278	6	de	de	X
dti-1333	278	7	groot	groot	PROPN
dti-1333	278	8	,	,	PUNCT
dti-1333	278	9	e.	e.	PROPN
dti-1333	278	10	,	,	PUNCT
dti-1333	278	11	van	van	PROPN
dti-1333	278	12	der	der	PROPN
dti-1333	278	13	steeg	steeg	PROPN
dti-1333	278	14	,	,	PUNCT
dti-1333	278	15	w.	w.	PROPN
dti-1333	278	16	et	et	PROPN
dti-1333	278	17	al	al	PROPN
dti-1333	278	18	.	.	PROPN
dti-1333	278	19	2005	2005	NUM
dti-1333	278	20	.	.	PUNCT
dti-1333	279	1	inherited	inherit	VERB
dti-1333	279	2	disorders	disorder	NOUN
dti-1333	279	3	of	of	ADP
dti-1333	279	4	hdl	hdl	PROPN
dti-1333	279	5	metabolism	metabolism	NOUN
dti-1333	279	6	and	and	CCONJ
dti-1333	279	7	atherosclerosis	atherosclerosis	NOUN
dti-1333	279	8	.	.	PUNCT
dti-1333	280	1	curr	curr	PROPN
dti-1333	280	2	.	.	PUNCT
dti-1333	281	1	opin	opin	NOUN
dti-1333	281	2	.	.	PUNCT
dti-1333	282	1	lipidol	lipidol	PROPN
dti-1333	282	2	.	.	PUNCT
dti-1333	283	1	,	,	PUNCT
dti-1333	283	2	16:139–45	16:139–45	PROPN
dti-1333	283	3	.	.	PUNCT
dti-1333	283	4	klon	klon	PROPN
dti-1333	283	5	,	,	PUNCT
dti-1333	283	6	a.e	a.e	PROPN
dti-1333	283	7	.	.	PROPN
dti-1333	283	8	,	,	PUNCT
dti-1333	283	9	jones	jones	PROPN
dti-1333	283	10	,	,	PUNCT
dti-1333	283	11	m.k	m.k	PROPN
dti-1333	283	12	.	.	PROPN
dti-1333	283	13	,	,	PUNCT
dti-1333	283	14	segrest	segrest	PROPN
dti-1333	283	15	,	,	PUNCT
dti-1333	283	16	j.p	j.p	PROPN
dti-1333	283	17	.	.	PROPN
dti-1333	283	18	et	et	PROPN
dti-1333	283	19	al	al	PROPN
dti-1333	283	20	.	.	PROPN
dti-1333	283	21	2000	2000	NUM
dti-1333	283	22	.	.	PUNCT
dti-1333	284	1	molecular	molecular	ADJ
dti-1333	284	2	belt	belt	NOUN
dti-1333	284	3	models	model	NOUN
dti-1333	284	4	for	for	ADP
dti-1333	284	5	the	the	DET
dti-1333	284	6	apolipoprotein	apolipoprotein	ADJ
dti-1333	284	7	a	a	PROPN
dti-1333	284	8	-	-	PUNCT
dti-1333	284	9	i	i	PRON
dti-1333	284	10	paris	paris	PROPN
dti-1333	284	11	and	and	CCONJ
dti-1333	284	12	milano	milano	PROPN
dti-1333	284	13	mutations	mutation	NOUN
dti-1333	284	14	.	.	PUNCT
dti-1333	285	1	biophys	biophy	NOUN
dti-1333	285	2	.	.	PUNCT
dti-1333	286	1	j.	j.	PROPN
dti-1333	286	2	,	,	PUNCT
dti-1333	286	3	79:1679–85	79:1679–85	NOUN
dti-1333	286	4	.	.	PUNCT
dti-1333	287	1	kodama	kodama	PROPN
dti-1333	287	2	,	,	PUNCT
dti-1333	287	3	s.	s.	PROPN
dti-1333	287	4	,	,	PUNCT
dti-1333	287	5	tanaka	tanaka	PROPN
dti-1333	287	6	,	,	PUNCT
dti-1333	287	7	s.	s.	PROPN
dti-1333	287	8	,	,	PUNCT
dti-1333	287	9	saito	saito	PROPN
dti-1333	287	10	,	,	PUNCT
dti-1333	287	11	k.	k.	PROPN
dti-1333	287	12	et	et	PROPN
dti-1333	287	13	al	al	PROPN
dti-1333	287	14	.	.	PROPN
dti-1333	287	15	2007	2007	NUM
dti-1333	287	16	.	.	PUNCT
dti-1333	288	1	effect	effect	NOUN
dti-1333	288	2	of	of	ADP
dti-1333	288	3	aerobic	aerobic	ADJ
dti-1333	288	4	exercise	exercise	NOUN
dti-1333	288	5	training	training	NOUN
dti-1333	288	6	on	on	ADP
dti-1333	288	7	serum	serum	NOUN
dti-1333	288	8	levels	level	NOUN
dti-1333	288	9	of	of	ADP
dti-1333	288	10	high	high	ADJ
dti-1333	288	11	-	-	PUNCT
dti-1333	288	12	density	density	NOUN
dti-1333	288	13	lipoprotein	lipoprotein	ADJ
dti-1333	288	14	cholesterol	cholesterol	NOUN
dti-1333	288	15	:	:	PUNCT
dti-1333	288	16	a	a	DET
dti-1333	288	17	meta	meta	ADJ
dti-1333	288	18	-	-	PUNCT
dti-1333	288	19	analysis	analysis	NOUN
dti-1333	288	20	.	.	PUNCT
dti-1333	289	1	arch	arch	NOUN
dti-1333	289	2	.	.	PUNCT
dti-1333	290	1	intern	intern	NOUN
dti-1333	290	2	.	.	PUNCT
dti-1333	291	1	med	med	PROPN
dti-1333	291	2	.	.	PROPN
dti-1333	291	3	,	,	PUNCT
dti-1333	291	4	167:999–1008	167:999–1008	NOUN
dti-1333	291	5	.	.	PUNCT
dti-1333	292	1	53	53	NUM
dti-1333	292	2	therapies	therapy	NOUN
dti-1333	292	3	to	to	PART
dti-1333	292	4	increase	increase	VERB
dti-1333	292	5	apoa-1	apoa-1	NUM
dti-1333	292	6	and	and	CCONJ
dti-1333	292	7	hdl	hdl	PROPN
dti-1333	292	8	-	-	PUNCT
dti-1333	292	9	cholesterol	cholesterol	NOUN
dti-1333	292	10	levels	level	NOUN
dti-1333	292	11	drug	drug	NOUN
dti-1333	292	12	target	target	NOUN
dti-1333	292	13	insights	insight	NOUN
dti-1333	292	14	2008:3	2008:3	NUM
dti-1333	292	15	kolovou	kolovou	PROPN
dti-1333	292	16	,	,	PUNCT
dti-1333	292	17	g.d	g.d	PROPN
dti-1333	292	18	.	.	PROPN
dti-1333	292	19	,	,	PUNCT
dti-1333	292	20	mikhailidis	mikhailidis	PROPN
dti-1333	292	21	,	,	PUNCT
dti-1333	292	22	d.p	d.p	PROPN
dti-1333	292	23	.	.	PROPN
dti-1333	292	24	,	,	PUNCT
dti-1333	292	25	anagnostopoulou	anagnostopoulou	PROPN
dti-1333	292	26	,	,	PUNCT
dti-1333	292	27	k.k	k.k	PROPN
dti-1333	292	28	.	.	PROPN
dti-1333	292	29	et	et	PROPN
dti-1333	292	30	al	al	PROPN
dti-1333	292	31	.	.	PROPN
dti-1333	292	32	2006	2006	NUM
dti-1333	292	33	.	.	PUNCT
dti-1333	293	1	tangier	tangy	ADJ
dti-1333	293	2	disease	disease	NOUN
dti-1333	293	3	four	four	NUM
dti-1333	293	4	decades	decade	NOUN
dti-1333	293	5	of	of	ADP
dti-1333	293	6	research	research	NOUN
dti-1333	293	7	:	:	PUNCT
dti-1333	293	8	a	a	DET
dti-1333	293	9	refl	refl	ADJ
dti-1333	293	10	ection	ection	NOUN
dti-1333	293	11	of	of	ADP
dti-1333	293	12	the	the	DET
dti-1333	293	13	importance	importance	NOUN
dti-1333	293	14	of	of	ADP
dti-1333	293	15	hdl	hdl	PROPN
dti-1333	293	16	.	.	PUNCT
dti-1333	294	1	curr	curr	AUX
dti-1333	294	2	.	.	PUNCT
dti-1333	294	3	med	med	PROPN
dti-1333	294	4	.	.	PROPN
dti-1333	294	5	chem	chem	PROPN
dti-1333	294	6	.	.	PUNCT
dti-1333	294	7	,	,	PUNCT
dti-1333	295	1	13:771–82	13:771–82	PROPN
dti-1333	295	2	.	.	PUNCT
dti-1333	296	1	lai	lai	PROPN
dti-1333	296	2	,	,	PUNCT
dti-1333	296	3	c.q	c.q	PROPN
dti-1333	296	4	.	.	PROPN
dti-1333	296	5	,	,	PUNCT
dti-1333	296	6	parnell	parnell	PROPN
dti-1333	296	7	,	,	PUNCT
dti-1333	296	8	l.d	l.d	PROPN
dti-1333	296	9	.	.	PROPN
dti-1333	296	10	and	and	CCONJ
dti-1333	296	11	ordovas	ordovas	PROPN
dti-1333	296	12	,	,	PUNCT
dti-1333	296	13	j.m	j.m	PROPN
dti-1333	296	14	.	.	PROPN
dti-1333	296	15	2005	2005	NUM
dti-1333	296	16	.	.	PUNCT
dti-1333	297	1	the	the	DET
dti-1333	297	2	apoa1	apoa1	PROPN
dti-1333	297	3	/	/	SYM
dti-1333	297	4	c3	c3	PROPN
dti-1333	297	5	/	/	SYM
dti-1333	297	6	a4	a4	PROPN
dti-1333	297	7	/	/	SYM
dti-1333	297	8	a5	a5	NOUN
dti-1333	297	9	gene	gene	NOUN
dti-1333	297	10	cluster	cluster	NOUN
dti-1333	297	11	,	,	PUNCT
dti-1333	297	12	lipid	lipid	NOUN
dti-1333	297	13	metabolism	metabolism	NOUN
dti-1333	297	14	and	and	CCONJ
dti-1333	297	15	cardiovascular	cardiovascular	ADJ
dti-1333	297	16	disease	disease	NOUN
dti-1333	297	17	risk	risk	NOUN
dti-1333	297	18	.	.	PUNCT
dti-1333	298	1	curr	curr	PROPN
dti-1333	298	2	.	.	PUNCT
dti-1333	299	1	opin	opin	NOUN
dti-1333	299	2	.	.	PUNCT
dti-1333	300	1	lipidol	lipidol	PROPN
dti-1333	300	2	.	.	PUNCT
dti-1333	300	3	,	,	PUNCT
dti-1333	300	4	16:153–66	16:153–66	PROPN
dti-1333	300	5	.	.	PUNCT
dti-1333	301	1	lamon	lamon	PROPN
dti-1333	301	2	-	-	PUNCT
dti-1333	301	3	fava	fava	PROPN
dti-1333	301	4	,	,	PUNCT
dti-1333	301	5	s.	s.	PROPN
dti-1333	301	6	,	,	PUNCT
dti-1333	301	7	postfai	postfai	NOUN
dti-1333	301	8	,	,	PUNCT
dti-1333	301	9	b.	b.	PROPN
dti-1333	301	10	,	,	PUNCT
dti-1333	301	11	diffenderfer	diffenderfer	NOUN
dti-1333	301	12	,	,	PUNCT
dti-1333	301	13	m.	m.	NOUN
dti-1333	301	14	et	et	PROPN
dti-1333	301	15	al	al	PROPN
dti-1333	301	16	.	.	PROPN
dti-1333	301	17	2006	2006	NUM
dti-1333	301	18	.	.	PUNCT
dti-1333	302	1	role	role	NOUN
dti-1333	302	2	of	of	ADP
dti-1333	302	3	the	the	DET
dti-1333	302	4	estrogen	estrogen	NOUN
dti-1333	302	5	and	and	CCONJ
dti-1333	302	6	progestin	progestin	NOUN
dti-1333	302	7	in	in	ADP
dti-1333	302	8	hormonal	hormonal	ADJ
dti-1333	302	9	replacement	replacement	NOUN
dti-1333	302	10	therapy	therapy	NOUN
dti-1333	302	11	on	on	ADP
dti-1333	302	12	apolipoprotein	apolipoprotein	ADJ
dti-1333	302	13	a	a	PRON
dti-1333	302	14	-	-	PUNCT
dti-1333	302	15	i	i	PRON
dti-1333	302	16	kinetics	kinetic	NOUN
dti-1333	302	17	in	in	ADP
dti-1333	302	18	postmenopausal	postmenopausal	ADJ
dti-1333	302	19	women	woman	NOUN
dti-1333	302	20	.	.	PUNCT
dti-1333	303	1	arterioscler	arterioscler	PROPN
dti-1333	303	2	.	.	PUNCT
dti-1333	304	1	thromb	thromb	PROPN
dti-1333	304	2	.	.	PUNCT
dti-1333	305	1	vasc	vasc	PROPN
dti-1333	305	2	.	.	PUNCT
dti-1333	306	1	biol	biol	PROPN
dti-1333	306	2	.	.	PUNCT
dti-1333	306	3	,	,	PUNCT
dti-1333	306	4	26:385–91	26:385–91	PROPN
dti-1333	306	5	.	.	PUNCT
dti-1333	307	1	mccormack	mccormack	PROPN
dti-1333	307	2	,	,	PUNCT
dti-1333	307	3	p.l	p.l	PROPN
dti-1333	307	4	.	.	PROPN
dti-1333	307	5	and	and	CCONJ
dti-1333	307	6	keating	keating	PROPN
dti-1333	307	7	,	,	PUNCT
dti-1333	307	8	g.m	g.m	PROPN
dti-1333	307	9	.	.	PROPN
dti-1333	307	10	2005	2005	NUM
dti-1333	307	11	.	.	PUNCT
dti-1333	308	1	prolonged	prolong	VERB
dti-1333	308	2	-	-	PUNCT
dti-1333	308	3	release	release	NOUN
dti-1333	308	4	nicotinic	nicotinic	ADJ
dti-1333	308	5	acid	acid	NOUN
dti-1333	308	6	:	:	PUNCT
dti-1333	308	7	a	a	DET
dti-1333	308	8	review	review	NOUN
dti-1333	308	9	of	of	ADP
dti-1333	308	10	its	its	PRON
dti-1333	308	11	use	use	NOUN
dti-1333	308	12	in	in	ADP
dti-1333	308	13	the	the	DET
dti-1333	308	14	treatment	treatment	NOUN
dti-1333	308	15	of	of	ADP
dti-1333	308	16	dyslipidaemia	dyslipidaemia	NOUN
dti-1333	308	17	.	.	PUNCT
dti-1333	309	1	drugs	drug	NOUN
dti-1333	309	2	,	,	PUNCT
dti-1333	309	3	65:2719–40	65:2719–40	NUM
dti-1333	309	4	.	.	PUNCT
dti-1333	310	1	maejima	maejima	PROPN
dti-1333	310	2	,	,	PUNCT
dti-1333	310	3	t.	t.	PROPN
dti-1333	310	4	,	,	PUNCT
dti-1333	310	5	yamazaki	yamazaki	PROPN
dti-1333	310	6	,	,	PUNCT
dti-1333	310	7	h.	h.	PROPN
dti-1333	310	8	,	,	PUNCT
dti-1333	310	9	aoki	aoki	PROPN
dti-1333	310	10	,	,	PUNCT
dti-1333	310	11	t.	t.	PROPN
dti-1333	310	12	et	et	PROPN
dti-1333	310	13	al	al	PROPN
dti-1333	310	14	.	.	PROPN
dti-1333	310	15	2004	2004	NUM
dti-1333	310	16	.	.	PUNCT
dti-1333	311	1	effect	effect	NOUN
dti-1333	311	2	of	of	ADP
dti-1333	311	3	pitavastatin	pitavastatin	NOUN
dti-1333	311	4	on	on	ADP
dti-1333	311	5	apolipoprotein	apolipoprotein	ADJ
dti-1333	311	6	a	a	DET
dti-1333	311	7	-	-	PUNCT
dti-1333	311	8	i	i	PRON
dti-1333	311	9	production	production	NOUN
dti-1333	311	10	in	in	ADP
dti-1333	311	11	hepg2	hepg2	NOUN
dti-1333	311	12	cells	cell	NOUN
dti-1333	311	13	.	.	PUNCT
dti-1333	312	1	biochem	biochem	PROPN
dti-1333	312	2	.	.	PUNCT
dti-1333	313	1	biophys	biophy	NOUN
dti-1333	313	2	.	.	PUNCT
dti-1333	314	1	res	re	NOUN
dti-1333	314	2	.	.	PUNCT
dti-1333	315	1	commun	commun	PROPN
dti-1333	315	2	.	.	PROPN
dti-1333	316	1	,	,	PUNCT
dti-1333	316	2	324:835–9	324:835–9	NUM
dti-1333	316	3	.	.	PUNCT
dti-1333	317	1	manach	manach	ADV
dti-1333	317	2	,	,	PUNCT
dti-1333	317	3	c.	c.	PROPN
dti-1333	317	4	,	,	PUNCT
dti-1333	317	5	mazur	mazur	PROPN
dti-1333	317	6	,	,	PUNCT
dti-1333	317	7	a.	a.	NOUN
dti-1333	317	8	and	and	CCONJ
dti-1333	317	9	scalbert	scalbert	NOUN
dti-1333	317	10	,	,	PUNCT
dti-1333	317	11	a.	a.	NOUN
dti-1333	317	12	2005	2005	NUM
dti-1333	317	13	.	.	PUNCT
dti-1333	318	1	polyphenols	polyphenol	NOUN
dti-1333	318	2	and	and	CCONJ
dti-1333	318	3	prevention	prevention	NOUN
dti-1333	318	4	of	of	ADP
dti-1333	318	5	cardiovascular	cardiovascular	ADJ
dti-1333	318	6	diseases	disease	NOUN
dti-1333	318	7	.	.	PUNCT
dti-1333	319	1	curr	curr	PROPN
dti-1333	319	2	.	.	PUNCT
dti-1333	320	1	opin	opin	NOUN
dti-1333	320	2	.	.	PUNCT
dti-1333	321	1	lipidol	lipidol	PROPN
dti-1333	321	2	.	.	PUNCT
dti-1333	322	1	,	,	PUNCT
dti-1333	322	2	16:77–84	16:77–84	PROPN
dti-1333	322	3	.	.	PUNCT
dti-1333	323	1	mooradian	mooradian	PROPN
dti-1333	323	2	,	,	PUNCT
dti-1333	323	3	a.d	a.d	PROPN
dti-1333	323	4	.	.	PROPN
dti-1333	323	5	,	,	PUNCT
dti-1333	323	6	haas	haas	PROPN
dti-1333	323	7	,	,	PUNCT
dti-1333	323	8	m.j	m.j	PROPN
dti-1333	323	9	.	.	PROPN
dti-1333	323	10	and	and	CCONJ
dti-1333	323	11	wong	wong	PROPN
dti-1333	323	12	,	,	PUNCT
dti-1333	323	13	n.c	n.c	PROPN
dti-1333	323	14	.	.	PROPN
dti-1333	323	15	2006	2006	NUM
dti-1333	323	16	.	.	PUNCT
dti-1333	324	1	the	the	DET
dti-1333	324	2	effect	effect	NOUN
dti-1333	324	3	of	of	ADP
dti-1333	324	4	select	select	ADJ
dti-1333	324	5	nutrients	nutrient	NOUN
dti-1333	324	6	on	on	ADP
dti-1333	324	7	serum	serum	NOUN
dti-1333	324	8	high	high	ADJ
dti-1333	324	9	-	-	PUNCT
dti-1333	324	10	density	density	NOUN
dti-1333	324	11	lipoprotein	lipoprotein	ADJ
dti-1333	324	12	cholesterol	cholesterol	NOUN
dti-1333	324	13	and	and	CCONJ
dti-1333	324	14	apolipoprotein	apolipoprotein	VERB
dti-1333	324	15	a	a	DET
dti-1333	324	16	-	-	PUNCT
dti-1333	324	17	i	i	NOUN
dti-1333	324	18	levels	level	NOUN
dti-1333	324	19	.	.	PUNCT
dti-1333	325	1	endocr	endocr	PROPN
dti-1333	325	2	.	.	PUNCT
dti-1333	326	1	rev	rev	PROPN
dti-1333	326	2	.	.	PROPN
dti-1333	326	3	,	,	PUNCT
dti-1333	326	4	27:2–16	27:2–16	PROPN
dti-1333	326	5	.	.	PUNCT
dti-1333	327	1	nagano	nagano	PROPN
dti-1333	327	2	,	,	PUNCT
dti-1333	327	3	m.	m.	NOUN
dti-1333	327	4	,	,	PUNCT
dti-1333	327	5	yamashita	yamashita	PROPN
dti-1333	327	6	,	,	PUNCT
dti-1333	327	7	s.	s.	PROPN
dti-1333	327	8	,	,	PUNCT
dti-1333	327	9	hirano	hirano	PROPN
dti-1333	327	10	,	,	PUNCT
dti-1333	327	11	k.	k.	PROPN
dti-1333	327	12	et	et	PROPN
dti-1333	327	13	al	al	PROPN
dti-1333	327	14	.	.	PROPN
dti-1333	327	15	2004	2004	NUM
dti-1333	327	16	.	.	PUNCT
dti-1333	328	1	molecular	molecular	ADJ
dti-1333	328	2	mechanisms	mechanism	NOUN
dti-1333	328	3	of	of	ADP
dti-1333	328	4	cholesteryl	cholesteryl	NOUN
dti-1333	328	5	ester	ester	NOUN
dti-1333	328	6	transfer	transfer	NOUN
dti-1333	328	7	protein	protein	NOUN
dti-1333	328	8	defi	defi	NOUN
dti-1333	328	9	ciency	ciency	NOUN
dti-1333	328	10	in	in	ADP
dti-1333	328	11	the	the	DET
dti-1333	328	12	japanese	japanese	PROPN
dti-1333	328	13	.	.	PUNCT
dti-1333	329	1	j.	j.	PROPN
dti-1333	329	2	atheroscler	atheroscler	PROPN
dti-1333	329	3	.	.	PUNCT
dti-1333	330	1	thromb	thromb	PROPN
dti-1333	330	2	.	.	PUNCT
dti-1333	330	3	,	,	PUNCT
dti-1333	330	4	11:110–21	11:110–21	PROPN
dti-1333	330	5	.	.	PUNCT
dti-1333	331	1	nicholls	nicholls	PROPN
dti-1333	331	2	,	,	PUNCT
dti-1333	331	3	s.j	s.j	PROPN
dti-1333	331	4	.	.	PROPN
dti-1333	331	5	and	and	CCONJ
dti-1333	331	6	nissen	nissen	PROPN
dti-1333	331	7	,	,	PUNCT
dti-1333	331	8	s.e	s.e	PROPN
dti-1333	331	9	.	.	PROPN
dti-1333	331	10	2007	2007	NUM
dti-1333	331	11	.	.	PUNCT
dti-1333	332	1	new	new	ADJ
dti-1333	332	2	targets	target	NOUN
dti-1333	332	3	of	of	ADP
dti-1333	332	4	high	high	ADJ
dti-1333	332	5	-	-	PUNCT
dti-1333	332	6	density	density	NOUN
dti-1333	332	7	lipoprotein	lipoprotein	ADJ
dti-1333	332	8	therapy	therapy	NOUN
dti-1333	332	9	.	.	PUNCT
dti-1333	333	1	curr	curr	PROPN
dti-1333	333	2	.	.	PUNCT
dti-1333	334	1	opin	opin	NOUN
dti-1333	334	2	.	.	PUNCT
dti-1333	335	1	lipidol	lipidol	PROPN
dti-1333	335	2	.	.	PUNCT
dti-1333	336	1	,	,	PUNCT
dti-1333	337	1	18:421–6	18:421–6	NUM
dti-1333	337	2	.	.	PUNCT
dti-1333	338	1	nicholls	nicholls	PROPN
dti-1333	338	2	,	,	PUNCT
dti-1333	338	3	s.j	s.j	PROPN
dti-1333	338	4	.	.	PROPN
dti-1333	338	5	,	,	PUNCT
dti-1333	338	6	cutri	cutri	PROPN
dti-1333	338	7	,	,	PUNCT
dti-1333	338	8	b.	b.	PROPN
dti-1333	338	9	,	,	PUNCT
dti-1333	338	10	worthley	worthley	PROPN
dti-1333	338	11	,	,	PUNCT
dti-1333	338	12	s.g	s.g	PROPN
dti-1333	338	13	.	.	PROPN
dti-1333	338	14	et	et	PROPN
dti-1333	338	15	al	al	PROPN
dti-1333	338	16	.	.	PROPN
dti-1333	338	17	2005	2005	NUM
dti-1333	338	18	.	.	PUNCT
dti-1333	339	1	impact	impact	NOUN
dti-1333	339	2	of	of	ADP
dti-1333	339	3	short	short	ADJ
dti-1333	339	4	-	-	PUNCT
dti-1333	339	5	term	term	NOUN
dti-1333	339	6	administration	administration	NOUN
dti-1333	339	7	of	of	ADP
dti-1333	339	8	high	high	ADJ
dti-1333	339	9	-	-	PUNCT
dti-1333	339	10	density	density	NOUN
dti-1333	339	11	lipoproteins	lipoprotein	NOUN
dti-1333	339	12	and	and	CCONJ
dti-1333	339	13	atorvastatin	atorvastatin	NOUN
dti-1333	339	14	on	on	ADP
dti-1333	339	15	atherosclerosis	atherosclerosis	NOUN
dti-1333	339	16	in	in	ADP
dti-1333	339	17	rabbits	rabbit	NOUN
dti-1333	339	18	.	.	PUNCT
dti-1333	340	1	arterioscler	arterioscler	NOUN
dti-1333	340	2	.	.	PUNCT
dti-1333	341	1	thromb	thromb	PROPN
dti-1333	341	2	.	.	PUNCT
dti-1333	342	1	vasc	vasc	PROPN
dti-1333	342	2	.	.	PUNCT
dti-1333	343	1	biol	biol	PROPN
dti-1333	343	2	.	.	PUNCT
dti-1333	343	3	,	,	PUNCT
dti-1333	343	4	25:2416–21	25:2416–21	NUM
dti-1333	343	5	.	.	PUNCT
dti-1333	343	6	nicholls	nicholls	PROPN
dti-1333	343	7	,	,	PUNCT
dti-1333	343	8	s.j	s.j	PROPN
dti-1333	343	9	.	.	PROPN
dti-1333	343	10	,	,	PUNCT
dti-1333	343	11	tuzcu	tuzcu	PROPN
dti-1333	343	12	,	,	PUNCT
dti-1333	343	13	e.m	e.m	PROPN
dti-1333	343	14	.	.	PROPN
dti-1333	343	15	,	,	PUNCT
dti-1333	343	16	sipahi	sipahi	PROPN
dti-1333	343	17	,	,	PUNCT
dti-1333	343	18	i.	i.	PROPN
dti-1333	343	19	et	et	PROPN
dti-1333	343	20	al	al	PROPN
dti-1333	343	21	.	.	PROPN
dti-1333	343	22	2006	2006	NUM
dti-1333	343	23	.	.	PUNCT
dti-1333	344	1	relationship	relationship	NOUN
dti-1333	344	2	between	between	ADP
dti-1333	344	3	atheroma	atheroma	NOUN
dti-1333	344	4	regression	regression	NOUN
dti-1333	344	5	and	and	CCONJ
dti-1333	344	6	change	change	NOUN
dti-1333	344	7	in	in	ADP
dti-1333	344	8	lumen	luman	NOUN
dti-1333	344	9	size	size	NOUN
dti-1333	344	10	after	after	ADP
dti-1333	344	11	infusion	infusion	NOUN
dti-1333	344	12	of	of	ADP
dti-1333	344	13	apolipoprotein	apolipoprotein	ADJ
dti-1333	344	14	a	a	PROPN
dti-1333	344	15	-	-	PUNCT
dti-1333	344	16	i	i	PRON
dti-1333	344	17	milano	milano	PROPN
dti-1333	344	18	.	.	PUNCT
dti-1333	345	1	j.	j.	PROPN
dti-1333	345	2	am	am	PROPN
dti-1333	345	3	.	.	PUNCT
dti-1333	346	1	coll	coll	PROPN
dti-1333	346	2	.	.	PUNCT
dti-1333	347	1	cardiol	cardiol	PROPN
dti-1333	347	2	.	.	PUNCT
dti-1333	347	3	,	,	PUNCT
dti-1333	348	1	47:992–7	47:992–7	NUM
dti-1333	348	2	.	.	PUNCT
dti-1333	349	1	nicholls	nicholls	PROPN
dti-1333	349	2	,	,	PUNCT
dti-1333	349	3	s.j	s.j	PROPN
dti-1333	349	4	.	.	PROPN
dti-1333	349	5	,	,	PUNCT
dti-1333	349	6	tuzcu	tuzcu	PROPN
dti-1333	349	7	,	,	PUNCT
dti-1333	349	8	e.m	e.m	PROPN
dti-1333	349	9	.	.	PROPN
dti-1333	349	10	,	,	PUNCT
dti-1333	349	11	sipahi	sipahi	PROPN
dti-1333	349	12	,	,	PUNCT
dti-1333	349	13	i.	i.	PROPN
dti-1333	349	14	et	et	PROPN
dti-1333	349	15	al	al	PROPN
dti-1333	349	16	.	.	PROPN
dti-1333	349	17	2007	2007	NUM
dti-1333	349	18	.	.	PUNCT
dti-1333	350	1	statins	statin	NOUN
dti-1333	350	2	,	,	PUNCT
dti-1333	350	3	high	high	ADJ
dti-1333	350	4	-	-	PUNCT
dti-1333	350	5	density	density	NOUN
dti-1333	350	6	lipoprotein	lipoprotein	ADJ
dti-1333	350	7	cholesterol	cholesterol	NOUN
dti-1333	350	8	,	,	PUNCT
dti-1333	350	9	and	and	CCONJ
dti-1333	350	10	regression	regression	NOUN
dti-1333	350	11	of	of	ADP
dti-1333	350	12	coronary	coronary	ADJ
dti-1333	350	13	atherosclerosis	atherosclerosis	NOUN
dti-1333	350	14	.	.	PUNCT
dti-1333	351	1	jama	jama	NOUN
dti-1333	351	2	,	,	PUNCT
dti-1333	351	3	297:499–508	297:499–508	NUM
dti-1333	351	4	.	.	PUNCT
dti-1333	352	1	nissen	nissen	PROPN
dti-1333	352	2	,	,	PUNCT
dti-1333	352	3	s.e	s.e	PROPN
dti-1333	352	4	.	.	PROPN
dti-1333	352	5	,	,	PUNCT
dti-1333	352	6	nicholls	nicholls	PROPN
dti-1333	352	7	,	,	PUNCT
dti-1333	352	8	s.j	s.j	PROPN
dti-1333	352	9	.	.	PROPN
dti-1333	352	10	,	,	PUNCT
dti-1333	352	11	wolski	wolski	PROPN
dti-1333	352	12	,	,	PUNCT
dti-1333	352	13	k.	k.	PROPN
dti-1333	352	14	et	et	PROPN
dti-1333	352	15	al	al	PROPN
dti-1333	352	16	.	.	PROPN
dti-1333	352	17	2007a	2007a	NOUN
dti-1333	352	18	.	.	PUNCT
dti-1333	353	1	effects	effect	NOUN
dti-1333	353	2	of	of	ADP
dti-1333	353	3	a	a	DET
dti-1333	353	4	potent	potent	ADJ
dti-1333	353	5	and	and	CCONJ
dti-1333	353	6	selective	selective	ADJ
dti-1333	353	7	ppar	ppar	NOUN
dti-1333	353	8	-	-	PUNCT
dti-1333	353	9	alpha	alpha	NOUN
dti-1333	353	10	agonist	agonist	NOUN
dti-1333	353	11	in	in	ADP
dti-1333	353	12	patients	patient	NOUN
dti-1333	353	13	with	with	ADP
dti-1333	353	14	atherogenic	atherogenic	ADJ
dti-1333	353	15	dyslipidemia	dyslipidemia	NOUN
dti-1333	353	16	or	or	CCONJ
dti-1333	353	17	hypercholesterolemia	hypercholesterolemia	NOUN
dti-1333	353	18	:	:	PUNCT
dti-1333	353	19	two	two	NUM
dti-1333	353	20	randomized	randomize	VERB
dti-1333	353	21	controlled	control	VERB
dti-1333	353	22	trials	trial	NOUN
dti-1333	353	23	.	.	PUNCT
dti-1333	354	1	jama	jama	PROPN
dti-1333	354	2	,	,	PUNCT
dti-1333	354	3	297:1362–73	297:1362–73	PROPN
dti-1333	354	4	.	.	PUNCT
dti-1333	354	5	nissen	nissen	PROPN
dti-1333	354	6	,	,	PUNCT
dti-1333	354	7	s.e	s.e	PROPN
dti-1333	354	8	.	.	PROPN
dti-1333	354	9	,	,	PUNCT
dti-1333	354	10	tardif	tardif	PROPN
dti-1333	354	11	,	,	PUNCT
dti-1333	354	12	j.c	j.c	PROPN
dti-1333	354	13	.	.	PROPN
dti-1333	354	14	,	,	PUNCT
dti-1333	354	15	nicholls	nicholls	PROPN
dti-1333	354	16	,	,	PUNCT
dti-1333	354	17	s.j	s.j	PROPN
dti-1333	354	18	.	.	PROPN
dti-1333	354	19	et	et	PROPN
dti-1333	354	20	al	al	PROPN
dti-1333	354	21	.	.	PROPN
dti-1333	354	22	2007b	2007b	NUM
dti-1333	354	23	.	.	PUNCT
dti-1333	355	1	effect	effect	NOUN
dti-1333	355	2	of	of	ADP
dti-1333	355	3	torcetrapib	torcetrapib	ADJ
dti-1333	355	4	on	on	ADP
dti-1333	355	5	the	the	DET
dti-1333	355	6	progression	progression	NOUN
dti-1333	355	7	of	of	ADP
dti-1333	355	8	coronary	coronary	ADJ
dti-1333	355	9	atherosclerosis	atherosclerosis	NOUN
dti-1333	355	10	.	.	PUNCT
dti-1333	356	1	n.	n.	PROPN
dti-1333	356	2	engl	engl	PROPN
dti-1333	356	3	.	.	PUNCT
dti-1333	357	1	j.	j.	PROPN
dti-1333	357	2	med	med	PROPN
dti-1333	357	3	.	.	PROPN
dti-1333	357	4	,	,	PUNCT
dti-1333	357	5	356:1304–16	356:1304–16	PROPN
dti-1333	357	6	.	.	PUNCT
dti-1333	358	1	nissen	nissen	PROPN
dti-1333	358	2	,	,	PUNCT
dti-1333	358	3	s.e	s.e	PROPN
dti-1333	358	4	.	.	PROPN
dti-1333	358	5	,	,	PUNCT
dti-1333	358	6	tsunoda	tsunoda	PROPN
dti-1333	358	7	,	,	PUNCT
dti-1333	358	8	t.	t.	PROPN
dti-1333	358	9	,	,	PUNCT
dti-1333	358	10	tuzcu	tuzcu	PROPN
dti-1333	358	11	,	,	PUNCT
dti-1333	358	12	e.m	e.m	PROPN
dti-1333	358	13	.	.	PROPN
dti-1333	358	14	et	et	PROPN
dti-1333	358	15	al	al	PROPN
dti-1333	358	16	.	.	PROPN
dti-1333	358	17	2003	2003	NUM
dti-1333	358	18	.	.	PUNCT
dti-1333	359	1	effect	effect	NOUN
dti-1333	359	2	of	of	ADP
dti-1333	359	3	recombinant	recombinant	ADJ
dti-1333	359	4	apoa	apoa	NOUN
dti-1333	359	5	-	-	PUNCT
dti-1333	359	6	i	i	PRON
dti-1333	359	7	milano	milano	PROPN
dti-1333	359	8	on	on	ADP
dti-1333	359	9	coronary	coronary	ADJ
dti-1333	359	10	atherosclerosis	atherosclerosis	NOUN
dti-1333	359	11	in	in	ADP
dti-1333	359	12	patients	patient	NOUN
dti-1333	359	13	with	with	ADP
dti-1333	359	14	acute	acute	ADJ
dti-1333	359	15	coronary	coronary	ADJ
dti-1333	359	16	syndromes	syndrome	NOUN
dti-1333	359	17	:	:	PUNCT
dti-1333	359	18	a	a	DET
dti-1333	359	19	randomized	randomized	ADJ
dti-1333	359	20	controlled	control	VERB
dti-1333	359	21	trial	trial	NOUN
dti-1333	359	22	.	.	PUNCT
dti-1333	360	1	jama	jama	PROPN
dti-1333	360	2	,	,	PUNCT
dti-1333	360	3	290:2292–300	290:2292–300	NUM
dti-1333	360	4	.	.	PUNCT
dti-1333	361	1	oram	oram	PROPN
dti-1333	361	2	,	,	PUNCT
dti-1333	361	3	j.f	j.f	PROPN
dti-1333	361	4	.	.	PROPN
dti-1333	361	5	2000	2000	NUM
dti-1333	361	6	.	.	PUNCT
dti-1333	362	1	tangier	tangy	ADJ
dti-1333	362	2	disease	disease	NOUN
dti-1333	362	3	and	and	CCONJ
dti-1333	362	4	abca1	abca1	NOUN
dti-1333	362	5	.	.	PUNCT
dti-1333	363	1	biochim	biochim	PROPN
dti-1333	363	2	.	.	PUNCT
dti-1333	364	1	biophys	biophy	NOUN
dti-1333	364	2	.	.	PUNCT
dti-1333	365	1	acta	acta	PROPN
dti-1333	365	2	.	.	PROPN
dti-1333	365	3	,	,	PUNCT
dti-1333	365	4	1529:321–30	1529:321–30	NUM
dti-1333	365	5	.	.	PUNCT
dti-1333	366	1	oram	oram	PROPN
dti-1333	366	2	,	,	PUNCT
dti-1333	366	3	j.f	j.f	PROPN
dti-1333	366	4	.	.	PROPN
dti-1333	366	5	2001	2001	NUM
dti-1333	366	6	.	.	PUNCT
dti-1333	367	1	novel	novel	ADJ
dti-1333	367	2	approaches	approach	NOUN
dti-1333	367	3	to	to	ADP
dti-1333	367	4	treating	treat	VERB
dti-1333	367	5	cardiovascular	cardiovascular	ADJ
dti-1333	367	6	disease	disease	NOUN
dti-1333	367	7	:	:	PUNCT
dti-1333	367	8	lessons	lesson	NOUN
dti-1333	367	9	from	from	ADP
dti-1333	367	10	tangier	tangy	ADJ
dti-1333	367	11	disease	disease	NOUN
dti-1333	367	12	.	.	PUNCT
dti-1333	368	1	expert	expert	NOUN
dti-1333	368	2	opin	opin	NOUN
dti-1333	368	3	.	.	PUNCT
dti-1333	369	1	investig	investig	PROPN
dti-1333	369	2	.	.	PUNCT
dti-1333	370	1	drugs	drug	NOUN
dti-1333	370	2	,	,	PUNCT
dti-1333	370	3	10:427–38	10:427–38	PROPN
dti-1333	370	4	.	.	PUNCT
dti-1333	371	1	pal	pal	NOUN
dti-1333	371	2	,	,	PUNCT
dti-1333	371	3	m.	m.	NOUN
dti-1333	371	4	and	and	CCONJ
dti-1333	371	5	pillarisetti	pillarisetti	NOUN
dti-1333	371	6	,	,	PUNCT
dti-1333	371	7	s.	s.	PROPN
dti-1333	371	8	2007	2007	NUM
dti-1333	371	9	.	.	PUNCT
dti-1333	372	1	hdl	hdl	PROPN
dti-1333	372	2	elevators	elevator	NOUN
dti-1333	372	3	and	and	CCONJ
dti-1333	372	4	mimetics	mimetic	NOUN
dti-1333	372	5	-	-	PUNCT
dti-1333	372	6	emerging	emerge	VERB
dti-1333	372	7	therapies	therapy	NOUN
dti-1333	372	8	for	for	ADP
dti-1333	372	9	atherosclerosis	atherosclerosis	NOUN
dti-1333	372	10	.	.	PUNCT
dti-1333	373	1	cardiovasc	cardiovasc	PROPN
dti-1333	373	2	.	.	PROPN
dti-1333	373	3	hematol	hematol	NOUN
dti-1333	373	4	.	.	PUNCT
dti-1333	374	1	agents	agent	NOUN
dti-1333	374	2	med	me	VERB
dti-1333	374	3	.	.	PUNCT
dti-1333	374	4	chem	chem	PROPN
dti-1333	374	5	.	.	PUNCT
dti-1333	374	6	,	,	PUNCT
dti-1333	374	7	5:55–66	5:55–66	NUM
dti-1333	374	8	.	.	PUNCT
dti-1333	375	1	perez	perez	PROPN
dti-1333	375	2	-	-	PUNCT
dti-1333	375	3	mendez	mendez	PROPN
dti-1333	375	4	,	,	PUNCT
dti-1333	375	5	o.	o.	PROPN
dti-1333	375	6	,	,	PUNCT
dti-1333	375	7	bruckert	bruckert	PROPN
dti-1333	375	8	,	,	PUNCT
dti-1333	375	9	e.	e.	PROPN
dti-1333	375	10	,	,	PUNCT
dti-1333	375	11	franceschini	franceschini	PROPN
dti-1333	375	12	,	,	PUNCT
dti-1333	375	13	g.	g.	PROPN
dti-1333	375	14	et	et	PROPN
dti-1333	375	15	al	al	PROPN
dti-1333	375	16	.	.	PROPN
dti-1333	375	17	2000	2000	NUM
dti-1333	375	18	.	.	PUNCT
dti-1333	376	1	metabolism	metabolism	NOUN
dti-1333	376	2	of	of	ADP
dti-1333	376	3	apolipoproteins	apolipoprotein	NOUN
dti-1333	376	4	ai	ai	VERB
dti-1333	376	5	and	and	CCONJ
dti-1333	376	6	aii	aii	NOUN
dti-1333	376	7	in	in	ADP
dti-1333	376	8	subjects	subject	NOUN
dti-1333	376	9	carrying	carry	VERB
dti-1333	376	10	similar	similar	ADJ
dti-1333	376	11	apoai	apoai	ADJ
dti-1333	376	12	mutations	mutation	NOUN
dti-1333	376	13	,	,	PUNCT
dti-1333	376	14	apoai	apoai	VERB
dti-1333	376	15	milano	milano	PROPN
dti-1333	376	16	and	and	CCONJ
dti-1333	376	17	apoai	apoai	PROPN
dti-1333	376	18	paris	paris	PROPN
dti-1333	376	19	.	.	PUNCT
dti-1333	377	1	atherosclerosis	atherosclerosis	NOUN
dti-1333	377	2	,	,	PUNCT
dti-1333	377	3	148:317–25	148:317–25	NUM
dti-1333	377	4	.	.	PUNCT
dti-1333	377	5	poussier	poussier	PROPN
dti-1333	377	6	,	,	PUNCT
dti-1333	377	7	b.	b.	PROPN
dti-1333	377	8	,	,	PUNCT
dti-1333	377	9	cordova	cordova	PROPN
dti-1333	377	10	,	,	PUNCT
dti-1333	377	11	a.c	a.c	PROPN
dti-1333	377	12	.	.	PROPN
dti-1333	377	13	,	,	PUNCT
dti-1333	377	14	becquemin	becquemin	PROPN
dti-1333	377	15	,	,	PUNCT
dti-1333	377	16	j.p	j.p	PROPN
dti-1333	377	17	.	.	PROPN
dti-1333	377	18	et	et	PROPN
dti-1333	377	19	al	al	PROPN
dti-1333	377	20	.	.	PROPN
dti-1333	377	21	2005	2005	NUM
dti-1333	377	22	.	.	PUNCT
dti-1333	378	1	resveratrol	resveratrol	NOUN
dti-1333	378	2	inhibits	inhibit	VERB
dti-1333	378	3	vascular	vascular	ADJ
dti-1333	378	4	smooth	smooth	ADJ
dti-1333	378	5	muscle	muscle	NOUN
dti-1333	378	6	cell	cell	NOUN
dti-1333	378	7	proliferation	proliferation	NOUN
dti-1333	378	8	and	and	CCONJ
dti-1333	378	9	induces	induce	NOUN
dti-1333	378	10	apoptosis	apoptosis	NOUN
dti-1333	378	11	.	.	PUNCT
dti-1333	379	1	j.	j.	PROPN
dti-1333	379	2	vasc	vasc	PROPN
dti-1333	379	3	.	.	PROPN
dti-1333	379	4	surg	surg	PROPN
dti-1333	379	5	.	.	PUNCT
dti-1333	379	6	,	,	PUNCT
dti-1333	380	1	42:1190–7	42:1190–7	X
dti-1333	380	2	.	.	PUNCT
dti-1333	381	1	rader	rader	PROPN
dti-1333	381	2	,	,	PUNCT
dti-1333	381	3	d.j	d.j	PROPN
dti-1333	381	4	.	.	PROPN
dti-1333	381	5	2006	2006	NUM
dti-1333	381	6	.	.	PUNCT
dti-1333	382	1	molecular	molecular	ADJ
dti-1333	382	2	regulation	regulation	NOUN
dti-1333	382	3	of	of	ADP
dti-1333	382	4	hdl	hdl	PROPN
dti-1333	382	5	metabolism	metabolism	NOUN
dti-1333	382	6	and	and	CCONJ
dti-1333	382	7	function	function	NOUN
dti-1333	382	8	:	:	PUNCT
dti-1333	382	9	implications	implication	NOUN
dti-1333	382	10	for	for	ADP
dti-1333	382	11	novel	novel	ADJ
dti-1333	382	12	therapies	therapy	NOUN
dti-1333	382	13	.	.	PUNCT
dti-1333	383	1	j.	j.	PROPN
dti-1333	383	2	clin	clin	PROPN
dti-1333	383	3	.	.	PUNCT
dti-1333	384	1	invest	invest	PROPN
dti-1333	384	2	.	.	PUNCT
dti-1333	384	3	,	,	PUNCT
dti-1333	384	4	116:3090–100	116:3090–100	NUM
dti-1333	384	5	.	.	PUNCT
dti-1333	385	1	rader	rader	PROPN
dti-1333	385	2	,	,	PUNCT
dti-1333	385	3	d.j	d.j	PROPN
dti-1333	385	4	.	.	PROPN
dti-1333	385	5	2007a	2007a	NUM
dti-1333	385	6	.	.	PUNCT
dti-1333	386	1	mechanisms	mechanism	NOUN
dti-1333	386	2	of	of	ADP
dti-1333	386	3	disease	disease	NOUN
dti-1333	386	4	:	:	PUNCT
dti-1333	386	5	hdl	hdl	PROPN
dti-1333	386	6	metabolism	metabolism	NOUN
dti-1333	386	7	as	as	ADP
dti-1333	386	8	a	a	DET
dti-1333	386	9	target	target	NOUN
dti-1333	386	10	for	for	ADP
dti-1333	386	11	novel	novel	ADJ
dti-1333	386	12	therapies	therapy	NOUN
dti-1333	386	13	.	.	PUNCT
dti-1333	387	1	nat	nat	PROPN
dti-1333	387	2	.	.	PUNCT
dti-1333	388	1	clin	clin	PROPN
dti-1333	388	2	.	.	PUNCT
dti-1333	389	1	pract	pract	PROPN
dti-1333	389	2	.	.	PUNCT
dti-1333	390	1	cardiovasc	cardiovasc	PROPN
dti-1333	390	2	.	.	PROPN
dti-1333	390	3	med	med	PROPN
dti-1333	390	4	.	.	PROPN
dti-1333	390	5	,	,	PUNCT
dti-1333	391	1	4:102–9	4:102–9	PROPN
dti-1333	391	2	.	.	PROPN
dti-1333	391	3	rader	rader	PROPN
dti-1333	391	4	,	,	PUNCT
dti-1333	391	5	d.j	d.j	PROPN
dti-1333	391	6	.	.	PROPN
dti-1333	391	7	2007b	2007b	NUM
dti-1333	391	8	.	.	PUNCT
dti-1333	392	1	illuminating	illuminate	VERB
dti-1333	392	2	hdl	hdl	PROPN
dti-1333	392	3	—	—	PUNCT
dti-1333	392	4	is	be	AUX
dti-1333	392	5	it	it	PRON
dti-1333	392	6	still	still	ADV
dti-1333	392	7	a	a	DET
dti-1333	392	8	viable	viable	ADJ
dti-1333	392	9	therapeutic	therapeutic	ADJ
dti-1333	392	10	target	target	NOUN
dti-1333	392	11	?	?	PUNCT
dti-1333	393	1	new	new	ADJ
dti-1333	393	2	engl	engl	PROPN
dti-1333	393	3	.	.	PUNCT
dti-1333	394	1	j.	j.	PROPN
dti-1333	394	2	med	med	PROPN
dti-1333	394	3	.	.	PROPN
dti-1333	394	4	,	,	PUNCT
dti-1333	395	1	357:2180–83	357:2180–83	PROPN
dti-1333	395	2	.	.	PUNCT
dti-1333	395	3	renaud	renaud	PROPN
dti-1333	395	4	,	,	PUNCT
dti-1333	395	5	s.	s.	PROPN
dti-1333	395	6	and	and	CCONJ
dti-1333	395	7	de	de	PROPN
dti-1333	395	8	lorgeril	lorgeril	PROPN
dti-1333	395	9	,	,	PUNCT
dti-1333	395	10	m.	m.	NOUN
dti-1333	395	11	1992	1992	NUM
dti-1333	395	12	.	.	PUNCT
dti-1333	396	1	wine	wine	NOUN
dti-1333	396	2	,	,	PUNCT
dti-1333	396	3	alcohol	alcohol	NOUN
dti-1333	396	4	,	,	PUNCT
dti-1333	396	5	platelets	platelet	NOUN
dti-1333	396	6	,	,	PUNCT
dti-1333	396	7	and	and	CCONJ
dti-1333	396	8	the	the	DET
dti-1333	396	9	french	french	ADJ
dti-1333	396	10	paradox	paradox	NOUN
dti-1333	396	11	for	for	ADP
dti-1333	396	12	coronary	coronary	ADJ
dti-1333	396	13	heart	heart	NOUN
dti-1333	396	14	disease	disease	NOUN
dti-1333	396	15	.	.	PUNCT
dti-1333	397	1	lancet	lancet	PROPN
dti-1333	397	2	,	,	PUNCT
dti-1333	397	3	339:1523–6	339:1523–6	NUM
dti-1333	397	4	.	.	PUNCT
dti-1333	398	1	robins	robin	NOUN
dti-1333	398	2	,	,	PUNCT
dti-1333	398	3	s.j	s.j	PROPN
dti-1333	398	4	.	.	PROPN
dti-1333	398	5	,	,	PUNCT
dti-1333	398	6	collins	collins	PROPN
dti-1333	398	7	,	,	PUNCT
dti-1333	398	8	d.	d.	PROPN
dti-1333	398	9	,	,	PUNCT
dti-1333	398	10	wittes	wittes	PROPN
dti-1333	398	11	,	,	PUNCT
dti-1333	398	12	j.t	j.t	PROPN
dti-1333	398	13	.	.	PROPN
dti-1333	398	14	et	et	PROPN
dti-1333	398	15	al	al	PROPN
dti-1333	398	16	.	.	PROPN
dti-1333	398	17	2001	2001	NUM
dti-1333	398	18	.	.	PUNCT
dti-1333	399	1	veterans	veteran	NOUN
dti-1333	399	2	affairs	affair	VERB
dti-1333	399	3	highdensity	highdensity	NOUN
dti-1333	399	4	lipoprotein	lipoprotein	ADJ
dti-1333	399	5	intervention	intervention	NOUN
dti-1333	399	6	trial	trial	NOUN
dti-1333	399	7	.	.	PUNCT
dti-1333	400	1	relation	relation	NOUN
dti-1333	400	2	of	of	ADP
dti-1333	400	3	gemfi	gemfi	PROPN
dti-1333	400	4	brozil	brozil	NOUN
dti-1333	400	5	treatment	treatment	NOUN
dti-1333	400	6	and	and	CCONJ
dti-1333	400	7	lipid	lipid	NOUN
dti-1333	400	8	levels	level	NOUN
dti-1333	400	9	with	with	ADP
dti-1333	400	10	major	major	ADJ
dti-1333	400	11	coronary	coronary	ADJ
dti-1333	400	12	events	event	NOUN
dti-1333	400	13	:	:	PUNCT
dti-1333	400	14	va	va	NOUN
dti-1333	400	15	-	-	PUNCT
dti-1333	400	16	hit	hit	NOUN
dti-1333	400	17	:	:	PUNCT
dti-1333	400	18	a	a	DET
dti-1333	400	19	randomized	randomized	ADJ
dti-1333	400	20	controlled	control	VERB
dti-1333	400	21	trial	trial	NOUN
dti-1333	400	22	.	.	PUNCT
dti-1333	401	1	jama	jama	PROPN
dti-1333	401	2	,	,	PUNCT
dti-1333	401	3	285:1585–91	285:1585–91	NUM
dti-1333	401	4	.	.	PUNCT
dti-1333	402	1	rubin	rubin	PROPN
dti-1333	402	2	,	,	PUNCT
dti-1333	402	3	e.m	e.m	PROPN
dti-1333	402	4	.	.	PROPN
dti-1333	402	5	,	,	PUNCT
dti-1333	402	6	krauss	krauss	PROPN
dti-1333	402	7	,	,	PUNCT
dti-1333	402	8	r.m	r.m	PROPN
dti-1333	402	9	.	.	PROPN
dti-1333	402	10	,	,	PUNCT
dti-1333	402	11	spangler	spangler	PROPN
dti-1333	402	12	,	,	PUNCT
dti-1333	402	13	e.a	e.a	PROPN
dti-1333	402	14	.	.	PROPN
dti-1333	402	15	et	et	PROPN
dti-1333	402	16	al	al	PROPN
dti-1333	402	17	.	.	PROPN
dti-1333	402	18	1991	1991	NUM
dti-1333	402	19	.	.	PUNCT
dti-1333	403	1	inhibition	inhibition	NOUN
dti-1333	403	2	of	of	ADP
dti-1333	403	3	early	early	ADJ
dti-1333	403	4	atherogenesis	atherogenesis	NOUN
dti-1333	403	5	in	in	ADP
dti-1333	403	6	transgenic	transgenic	NOUN
dti-1333	403	7	mice	mouse	NOUN
dti-1333	403	8	by	by	ADP
dti-1333	403	9	human	human	ADJ
dti-1333	403	10	apolipoprotein	apolipoprotein	ADJ
dti-1333	403	11	ai	ai	PROPN
dti-1333	403	12	.	.	PUNCT
dti-1333	404	1	nature	nature	NOUN
dti-1333	404	2	,	,	PUNCT
dti-1333	404	3	353:265–7	353:265–7	NUM
dti-1333	404	4	.	.	PUNCT
dti-1333	405	1	rubins	rubin	NOUN
dti-1333	405	2	,	,	PUNCT
dti-1333	405	3	h.b	h.b	PROPN
dti-1333	405	4	.	.	PROPN
dti-1333	405	5	,	,	PUNCT
dti-1333	405	6	robins	robins	PROPN
dti-1333	405	7	,	,	PUNCT
dti-1333	405	8	s.j	s.j	PROPN
dti-1333	405	9	.	.	PROPN
dti-1333	405	10	,	,	PUNCT
dti-1333	405	11	collins	collins	PROPN
dti-1333	405	12	,	,	PUNCT
dti-1333	405	13	d.	d.	PROPN
dti-1333	405	14	et	et	PROPN
dti-1333	405	15	al	al	PROPN
dti-1333	405	16	.	.	PROPN
dti-1333	405	17	1999	1999	NUM
dti-1333	405	18	.	.	PUNCT
dti-1333	406	1	gemfi	gemfi	PROPN
dti-1333	406	2	brozil	brozil	VERB
dti-1333	406	3	for	for	ADP
dti-1333	406	4	the	the	DET
dti-1333	406	5	secondary	secondary	ADJ
dti-1333	406	6	prevention	prevention	NOUN
dti-1333	406	7	of	of	ADP
dti-1333	406	8	coronary	coronary	ADJ
dti-1333	406	9	heart	heart	NOUN
dti-1333	406	10	disease	disease	NOUN
dti-1333	406	11	in	in	ADP
dti-1333	406	12	men	man	NOUN
dti-1333	406	13	with	with	ADP
dti-1333	406	14	low	low	ADJ
dti-1333	406	15	levels	level	NOUN
dti-1333	406	16	of	of	ADP
dti-1333	406	17	high	high	ADJ
dti-1333	406	18	-	-	PUNCT
dti-1333	406	19	density	density	NOUN
dti-1333	406	20	lipoprotein	lipoprotein	ADJ
dti-1333	406	21	cholesterol	cholesterol	NOUN
dti-1333	406	22	.	.	PUNCT
dti-1333	407	1	veterans	veteran	NOUN
dti-1333	407	2	affairs	affair	VERB
dti-1333	407	3	highdensity	highdensity	NOUN
dti-1333	407	4	lipoprotein	lipoprotein	ADJ
dti-1333	407	5	cholesterol	cholesterol	NOUN
dti-1333	407	6	intervention	intervention	NOUN
dti-1333	407	7	trial	trial	NOUN
dti-1333	407	8	study	study	NOUN
dti-1333	407	9	group	group	NOUN
dti-1333	407	10	.	.	PUNCT
dti-1333	408	1	n.	n.	PROPN
dti-1333	408	2	engl	engl	PROPN
dti-1333	408	3	.	.	PUNCT
dti-1333	409	1	j.	j.	PROPN
dti-1333	409	2	med	med	PROPN
dti-1333	409	3	.	.	PROPN
dti-1333	409	4	,	,	PUNCT
dti-1333	409	5	341:410–8	341:410–8	NUM
dti-1333	409	6	.	.	PUNCT
dti-1333	410	1	scalbert	scalbert	PROPN
dti-1333	410	2	,	,	PUNCT
dti-1333	410	3	a.	a.	NOUN
dti-1333	410	4	,	,	PUNCT
dti-1333	410	5	manach	manach	ADV
dti-1333	410	6	,	,	PUNCT
dti-1333	410	7	c.	c.	PROPN
dti-1333	410	8	,	,	PUNCT
dti-1333	410	9	morand	morand	NOUN
dti-1333	410	10	,	,	PUNCT
dti-1333	410	11	c.	c.	PROPN
dti-1333	410	12	et	et	PROPN
dti-1333	410	13	al	al	PROPN
dti-1333	410	14	.	.	PROPN
dti-1333	410	15	2005	2005	NUM
dti-1333	410	16	.	.	PUNCT
dti-1333	411	1	dietary	dietary	ADJ
dti-1333	411	2	polyphenols	polyphenol	NOUN
dti-1333	411	3	and	and	CCONJ
dti-1333	411	4	the	the	DET
dti-1333	411	5	prevention	prevention	NOUN
dti-1333	411	6	of	of	ADP
dti-1333	411	7	diseases	disease	NOUN
dti-1333	411	8	.	.	PUNCT
dti-1333	412	1	crit	crit	PROPN
dti-1333	412	2	.	.	PUNCT
dti-1333	413	1	rev	rev	PROPN
dti-1333	413	2	.	.	PROPN
dti-1333	413	3	food	food	PROPN
dti-1333	413	4	sci	sci	PROPN
dti-1333	413	5	.	.	PUNCT
dti-1333	413	6	nutr	nutr	PROPN
dti-1333	413	7	.	.	PROPN
dti-1333	413	8	,	,	PUNCT
dti-1333	413	9	45:287–306	45:287–306	PROPN
dti-1333	413	10	.	.	PUNCT
dti-1333	414	1	schaefer	schaefer	PROPN
dti-1333	414	2	,	,	PUNCT
dti-1333	414	3	e.j	e.j	PROPN
dti-1333	414	4	.	.	PROPN
dti-1333	414	5	,	,	PUNCT
dti-1333	414	6	eisenberg	eisenberg	PROPN
dti-1333	414	7	,	,	PUNCT
dti-1333	414	8	s.	s.	PROPN
dti-1333	414	9	and	and	CCONJ
dti-1333	414	10	levy	levy	PROPN
dti-1333	414	11	,	,	PUNCT
dti-1333	414	12	r.i	r.i	PROPN
dti-1333	414	13	.	.	PROPN
dti-1333	414	14	1978	1978	NUM
dti-1333	414	15	.	.	PUNCT
dti-1333	415	1	lipoprotein	lipoprotein	ADJ
dti-1333	415	2	apoprotein	apoprotein	VERB
dti-1333	415	3	metabolism	metabolism	NOUN
dti-1333	415	4	.	.	PUNCT
dti-1333	416	1	j.	j.	PROPN
dti-1333	416	2	lipid	lipid	PROPN
dti-1333	416	3	res	res	PROPN
dti-1333	416	4	.	.	PROPN
dti-1333	416	5	,	,	PUNCT
dti-1333	416	6	19:667–87	19:667–87	NOUN
dti-1333	416	7	.	.	PUNCT
dti-1333	417	1	schäfer	schäfer	PROPN
dti-1333	417	2	,	,	PUNCT
dti-1333	417	3	c.	c.	PROPN
dti-1333	417	4	,	,	PUNCT
dti-1333	417	5	parlesak	parlesak	PROPN
dti-1333	417	6	,	,	PUNCT
dti-1333	417	7	a.	a.	NOUN
dti-1333	417	8	,	,	PUNCT
dti-1333	417	9	eckoldt	eckoldt	PROPN
dti-1333	417	10	,	,	PUNCT
dti-1333	417	11	j.	j.	PROPN
dti-1333	417	12	et	et	PROPN
dti-1333	417	13	al	al	PROPN
dti-1333	417	14	.	.	PROPN
dti-1333	417	15	2007	2007	NUM
dti-1333	417	16	.	.	PUNCT
dti-1333	418	1	beyond	beyond	ADP
dti-1333	418	2	hdl	hdl	NOUN
dti-1333	418	3	-	-	PUNCT
dti-1333	418	4	cholesterol	cholesterol	NOUN
dti-1333	418	5	increase	increase	NOUN
dti-1333	418	6	:	:	PUNCT
dti-1333	418	7	phospholipid	phospholipid	NOUN
dti-1333	418	8	enrichment	enrichment	NOUN
dti-1333	418	9	and	and	CCONJ
dti-1333	418	10	shift	shift	NOUN
dti-1333	418	11	from	from	ADP
dti-1333	418	12	hdl3	hdl3	NOUN
dti-1333	418	13	to	to	ADP
dti-1333	418	14	hdl2	hdl2	PROPN
dti-1333	418	15	in	in	ADP
dti-1333	418	16	alcohol	alcohol	NOUN
dti-1333	418	17	consumers	consumer	NOUN
dti-1333	418	18	.	.	PUNCT
dti-1333	419	1	j.	j.	PROPN
dti-1333	419	2	lipid	lipid	PROPN
dti-1333	419	3	res	res	PROPN
dti-1333	419	4	.	.	PROPN
dti-1333	419	5	,	,	PUNCT
dti-1333	419	6	48:1550–8	48:1550–8	NUM
dti-1333	419	7	.	.	PUNCT
dti-1333	420	1	schnatz	schnatz	PROPN
dti-1333	420	2	,	,	PUNCT
dti-1333	420	3	p.f	p.f	PROPN
dti-1333	420	4	.	.	PROPN
dti-1333	420	5	and	and	CCONJ
dti-1333	420	6	schnatz	schnatz	PROPN
dti-1333	420	7	,	,	PUNCT
dti-1333	420	8	j.d	j.d	PROPN
dti-1333	420	9	.	.	PROPN
dti-1333	420	10	2006	2006	NUM
dti-1333	420	11	.	.	PUNCT
dti-1333	421	1	dyslipidemia	dyslipidemia	VERB
dti-1333	421	2	in	in	ADP
dti-1333	421	3	menopause	menopause	NOUN
dti-1333	421	4	:	:	PUNCT
dti-1333	421	5	mechanisms	mechanism	NOUN
dti-1333	421	6	and	and	CCONJ
dti-1333	421	7	management	management	NOUN
dti-1333	421	8	.	.	PUNCT
dti-1333	422	1	obstet	obstet	PROPN
dti-1333	422	2	.	.	PUNCT
dti-1333	423	1	gynecol	gynecol	PROPN
dti-1333	423	2	.	.	PUNCT
dti-1333	424	1	surv	surv	PROPN
dti-1333	424	2	.	.	PUNCT
dti-1333	424	3	,	,	PUNCT
dti-1333	424	4	61:608–13	61:608–13	NOUN
dti-1333	424	5	.	.	PUNCT
dti-1333	425	1	schultz	schultz	PROPN
dti-1333	425	2	,	,	PUNCT
dti-1333	425	3	j.r	j.r	PROPN
dti-1333	425	4	.	.	PROPN
dti-1333	425	5	,	,	PUNCT
dti-1333	425	6	verstuyft	verstuyft	NOUN
dti-1333	425	7	,	,	PUNCT
dti-1333	425	8	j.g	j.g	PROPN
dti-1333	425	9	.	.	PROPN
dti-1333	425	10	,	,	PUNCT
dti-1333	425	11	gong	gong	PROPN
dti-1333	425	12	,	,	PUNCT
dti-1333	425	13	e.l	e.l	PROPN
dti-1333	425	14	.	.	PROPN
dti-1333	425	15	et	et	PROPN
dti-1333	425	16	al	al	PROPN
dti-1333	425	17	.	.	PROPN
dti-1333	425	18	1993	1993	NUM
dti-1333	425	19	.	.	PUNCT
dti-1333	426	1	protein	protein	NOUN
dti-1333	426	2	composition	composition	NOUN
dti-1333	426	3	determines	determine	VERB
dti-1333	426	4	the	the	DET
dti-1333	426	5	anti	anti	ADJ
dti-1333	426	6	-	-	ADJ
dti-1333	426	7	atherogenic	atherogenic	ADJ
dti-1333	426	8	properties	property	NOUN
dti-1333	426	9	of	of	ADP
dti-1333	426	10	hdl	hdl	NOUN
dti-1333	426	11	in	in	ADP
dti-1333	426	12	transgenic	transgenic	NOUN
dti-1333	426	13	mice	mouse	NOUN
dti-1333	426	14	.	.	PUNCT
dti-1333	427	1	nature	nature	NOUN
dti-1333	427	2	,	,	PUNCT
dti-1333	427	3	365:762–4	365:762–4	NUM
dti-1333	427	4	.	.	PUNCT
dti-1333	428	1	shah	shah	PROPN
dti-1333	428	2	,	,	PUNCT
dti-1333	428	3	p.k	p.k	PROPN
dti-1333	428	4	.	.	PROPN
dti-1333	428	5	2007a	2007a	NOUN
dti-1333	428	6	.	.	PUNCT
dti-1333	429	1	inhibition	inhibition	NOUN
dti-1333	429	2	of	of	ADP
dti-1333	429	3	cetp	cetp	NOUN
dti-1333	429	4	as	as	ADP
dti-1333	429	5	a	a	DET
dti-1333	429	6	novel	novel	ADJ
dti-1333	429	7	therapeutic	therapeutic	ADJ
dti-1333	429	8	strategy	strategy	NOUN
dti-1333	429	9	for	for	ADP
dti-1333	429	10	reducing	reduce	VERB
dti-1333	429	11	the	the	DET
dti-1333	429	12	risk	risk	NOUN
dti-1333	429	13	of	of	ADP
dti-1333	429	14	atherosclerotic	atherosclerotic	ADJ
dti-1333	429	15	disease	disease	NOUN
dti-1333	429	16	.	.	PUNCT
dti-1333	430	1	eur	eur	ADJ
dti-1333	430	2	.	.	PUNCT
dti-1333	431	1	heart	heart	PROPN
dti-1333	431	2	j.	j.	PROPN
dti-1333	431	3	,	,	PUNCT
dti-1333	431	4	28:5–12	28:5–12	PROPN
dti-1333	431	5	.	.	PUNCT
dti-1333	432	1	shah	shah	PROPN
dti-1333	432	2	,	,	PUNCT
dti-1333	432	3	p.k	p.k	PROPN
dti-1333	432	4	.	.	PROPN
dti-1333	432	5	2007b	2007b	NUM
dti-1333	432	6	.	.	PUNCT
dti-1333	433	1	apolipoprotein	apolipoprotein	VERB
dti-1333	433	2	a	a	DET
dti-1333	433	3	-	-	PUNCT
dti-1333	433	4	i	i	NOUN
dti-1333	433	5	/	/	SYM
dti-1333	433	6	hdl	hdl	PROPN
dti-1333	433	7	infusion	infusion	NOUN
dti-1333	433	8	therapy	therapy	NOUN
dti-1333	433	9	for	for	ADP
dti-1333	433	10	plaque	plaque	NOUN
dti-1333	433	11	stabilization	stabilization	NOUN
dti-1333	433	12	-	-	PUNCT
dti-1333	433	13	regression	regression	NOUN
dti-1333	433	14	:	:	PUNCT
dti-1333	433	15	a	a	DET
dti-1333	433	16	novel	novel	ADJ
dti-1333	433	17	therapeutic	therapeutic	ADJ
dti-1333	433	18	approach	approach	NOUN
dti-1333	433	19	.	.	PUNCT
dti-1333	434	1	curr	curr	PROPN
dti-1333	434	2	.	.	PUNCT
dti-1333	435	1	pharm	pharm	PROPN
dti-1333	435	2	.	.	PUNCT
dti-1333	436	1	des	des	PROPN
dti-1333	436	2	.	.	PROPN
dti-1333	436	3	,	,	PUNCT
dti-1333	436	4	13:1031–8	13:1031–8	NUM
dti-1333	436	5	.	.	PUNCT
dti-1333	437	1	shah	shah	PROPN
dti-1333	437	2	,	,	PUNCT
dti-1333	437	3	p.k	p.k	PROPN
dti-1333	437	4	.	.	PROPN
dti-1333	437	5	,	,	PUNCT
dti-1333	437	6	nilsson	nilsson	PROPN
dti-1333	437	7	,	,	PUNCT
dti-1333	437	8	j.	j.	PROPN
dti-1333	437	9	,	,	PUNCT
dti-1333	437	10	kaul	kaul	PROPN
dti-1333	437	11	,	,	PUNCT
dti-1333	437	12	s.	s.	PROPN
dti-1333	437	13	et	et	PROPN
dti-1333	437	14	al	al	PROPN
dti-1333	437	15	.	.	PROPN
dti-1333	437	16	1998	1998	NUM
dti-1333	437	17	.	.	PUNCT
dti-1333	438	1	effects	effect	NOUN
dti-1333	438	2	of	of	ADP
dti-1333	438	3	recombinant	recombinant	NOUN
dti-1333	438	4	apolipoprotein	apolipoprotein	ADJ
dti-1333	438	5	a	a	DET
dti-1333	438	6	-	-	PUNCT
dti-1333	438	7	i(milano	i(milano	NOUN
dti-1333	438	8	)	)	PUNCT
dti-1333	438	9	on	on	ADP
dti-1333	438	10	aortic	aortic	ADJ
dti-1333	438	11	atherosclerosis	atherosclerosis	NOUN
dti-1333	438	12	in	in	ADP
dti-1333	438	13	apolipoprotein	apolipoprotein	ADJ
dti-1333	438	14	e	e	NOUN
dti-1333	438	15	-	-	NOUN
dti-1333	438	16	defi	defi	ADJ
dti-1333	438	17	cient	cient	NOUN
dti-1333	438	18	mice	mouse	NOUN
dti-1333	438	19	.	.	PUNCT
dti-1333	439	1	circulation	circulation	NOUN
dti-1333	439	2	,	,	PUNCT
dti-1333	439	3	97:780–5	97:780–5	NUM
dti-1333	439	4	.	.	PUNCT
dti-1333	440	1	singh	singh	PROPN
dti-1333	440	2	,	,	PUNCT
dti-1333	440	3	i.m	i.m	PROPN
dti-1333	440	4	.	.	PROPN
dti-1333	440	5	,	,	PUNCT
dti-1333	440	6	shishehbor	shishehbor	PROPN
dti-1333	440	7	,	,	PUNCT
dti-1333	440	8	m.h	m.h	PROPN
dti-1333	440	9	.	.	PROPN
dti-1333	440	10	and	and	CCONJ
dti-1333	440	11	ansell	ansell	PROPN
dti-1333	440	12	,	,	PUNCT
dti-1333	440	13	b.j	b.j	PROPN
dti-1333	440	14	.	.	PROPN
dti-1333	440	15	2007	2007	NUM
dti-1333	440	16	.	.	PUNCT
dti-1333	441	1	high	high	ADJ
dti-1333	441	2	-	-	PUNCT
dti-1333	441	3	density	density	NOUN
dti-1333	441	4	lipoprotein	lipoprotein	NOUN
dti-1333	441	5	as	as	ADP
dti-1333	441	6	a	a	DET
dti-1333	441	7	therapeutic	therapeutic	ADJ
dti-1333	441	8	target	target	NOUN
dti-1333	441	9	:	:	PUNCT
dti-1333	441	10	a	a	DET
dti-1333	441	11	systematic	systematic	ADJ
dti-1333	441	12	review	review	NOUN
dti-1333	441	13	.	.	PUNCT
dti-1333	442	1	jama	jama	PROPN
dti-1333	442	2	,	,	PUNCT
dti-1333	442	3	298:786–98	298:786–98	NUM
dti-1333	442	4	.	.	PUNCT
dti-1333	443	1	slater	slater	PROPN
dti-1333	443	2	,	,	PUNCT
dti-1333	443	3	e.e	e.e	PROPN
dti-1333	443	4	.	.	PROPN
dti-1333	443	5	and	and	CCONJ
dti-1333	443	6	macdonald	macdonald	PROPN
dti-1333	443	7	,	,	PUNCT
dti-1333	443	8	j.s	j.s	PROPN
dti-1333	443	9	.	.	PROPN
dti-1333	443	10	1988	1988	NUM
dti-1333	443	11	.	.	PUNCT
dti-1333	444	1	mechanism	mechanism	NOUN
dti-1333	444	2	of	of	ADP
dti-1333	444	3	action	action	NOUN
dti-1333	444	4	and	and	CCONJ
dti-1333	444	5	biological	biological	ADJ
dti-1333	444	6	profi	profi	NOUN
dti-1333	444	7	le	le	PROPN
dti-1333	444	8	of	of	ADP
dti-1333	444	9	hmg	hmg	PROPN
dti-1333	444	10	coa	coa	NOUN
dti-1333	444	11	reductase	reductase	NOUN
dti-1333	444	12	inhibitors	inhibitor	NOUN
dti-1333	444	13	.	.	PUNCT
dti-1333	445	1	a	a	DET
dti-1333	445	2	new	new	ADJ
dti-1333	445	3	therapeutic	therapeutic	ADJ
dti-1333	445	4	alternative	alternative	NOUN
dti-1333	445	5	.	.	PUNCT
dti-1333	446	1	drugs	drug	NOUN
dti-1333	446	2	,	,	PUNCT
dti-1333	446	3	36(suppl	36(suppl	NUM
dti-1333	446	4	3):72–82	3):72–82	NUM
dti-1333	446	5	.	.	PUNCT
dti-1333	447	1	steinberg	steinberg	PROPN
dti-1333	447	2	,	,	PUNCT
dti-1333	447	3	d.	d.	PROPN
dti-1333	447	4	2004	2004	NUM
dti-1333	447	5	.	.	PUNCT
dti-1333	448	1	thematic	thematic	ADJ
dti-1333	448	2	review	review	NOUN
dti-1333	448	3	series	series	NOUN
dti-1333	448	4	:	:	PUNCT
dti-1333	448	5	the	the	DET
dti-1333	448	6	pathogenesis	pathogenesis	NOUN
dti-1333	448	7	of	of	ADP
dti-1333	448	8	atherosclerosis	atherosclerosis	NOUN
dti-1333	448	9	.	.	PUNCT
dti-1333	449	1	an	an	DET
dti-1333	449	2	interpretive	interpretive	ADJ
dti-1333	449	3	history	history	NOUN
dti-1333	449	4	of	of	ADP
dti-1333	449	5	the	the	DET
dti-1333	449	6	cholesterol	cholesterol	NOUN
dti-1333	449	7	controversy	controversy	NOUN
dti-1333	449	8	:	:	PUNCT
dti-1333	449	9	part	part	PROPN
dti-1333	449	10	i.	i.	PROPN
dti-1333	449	11	j.	j.	PROPN
dti-1333	449	12	lipid	lipid	PROPN
dti-1333	449	13	res	res	PROPN
dti-1333	449	14	.	.	PROPN
dti-1333	449	15	,	,	PUNCT
dti-1333	449	16	45:1583–93	45:1583–93	NUM
dti-1333	449	17	.	.	PUNCT
dti-1333	450	1	steinberg	steinberg	PROPN
dti-1333	450	2	,	,	PUNCT
dti-1333	450	3	d.	d.	PROPN
dti-1333	450	4	2005a	2005a	NUM
dti-1333	450	5	.	.	PUNCT
dti-1333	451	1	thematic	thematic	ADJ
dti-1333	451	2	review	review	NOUN
dti-1333	451	3	series	series	NOUN
dti-1333	451	4	:	:	PUNCT
dti-1333	451	5	the	the	DET
dti-1333	451	6	pathogenesis	pathogenesis	NOUN
dti-1333	451	7	of	of	ADP
dti-1333	451	8	atherosclerosis	atherosclerosis	NOUN
dti-1333	451	9	.	.	PUNCT
dti-1333	452	1	an	an	DET
dti-1333	452	2	interpretive	interpretive	ADJ
dti-1333	452	3	history	history	NOUN
dti-1333	452	4	of	of	ADP
dti-1333	452	5	the	the	DET
dti-1333	452	6	cholesterol	cholesterol	NOUN
dti-1333	452	7	controversy	controversy	NOUN
dti-1333	452	8	:	:	PUNCT
dti-1333	452	9	part	part	PROPN
dti-1333	452	10	ii	ii	PROPN
dti-1333	452	11	:	:	PUNCT
dti-1333	452	12	the	the	DET
dti-1333	452	13	early	early	ADJ
dti-1333	452	14	evidence	evidence	NOUN
dti-1333	452	15	linking	link	VERB
dti-1333	452	16	hypercholesterolemia	hypercholesterolemia	NOUN
dti-1333	452	17	to	to	ADP
dti-1333	452	18	coronary	coronary	ADJ
dti-1333	452	19	disease	disease	NOUN
dti-1333	452	20	in	in	ADP
dti-1333	452	21	humans	human	NOUN
dti-1333	452	22	.	.	PUNCT
dti-1333	453	1	j.	j.	PROPN
dti-1333	453	2	lipid	lipid	PROPN
dti-1333	453	3	res	res	PROPN
dti-1333	453	4	.	.	PROPN
dti-1333	453	5	,	,	PUNCT
dti-1333	453	6	46:179–90	46:179–90	PROPN
dti-1333	453	7	.	.	PUNCT
dti-1333	454	1	steinberg	steinberg	PROPN
dti-1333	454	2	,	,	PUNCT
dti-1333	454	3	d.	d.	PROPN
dti-1333	454	4	2005b	2005b	NUM
dti-1333	454	5	.	.	PUNCT
dti-1333	455	1	thematic	thematic	ADJ
dti-1333	455	2	review	review	NOUN
dti-1333	455	3	series	series	NOUN
dti-1333	455	4	:	:	PUNCT
dti-1333	455	5	the	the	DET
dti-1333	455	6	pathogenesis	pathogenesis	NOUN
dti-1333	455	7	of	of	ADP
dti-1333	455	8	atherosclerosis	atherosclerosis	NOUN
dti-1333	455	9	:	:	PUNCT
dti-1333	455	10	an	an	DET
dti-1333	455	11	interpretive	interpretive	ADJ
dti-1333	455	12	history	history	NOUN
dti-1333	455	13	of	of	ADP
dti-1333	455	14	the	the	DET
dti-1333	455	15	cholesterol	cholesterol	NOUN
dti-1333	455	16	controversy	controversy	NOUN
dti-1333	455	17	,	,	PUNCT
dti-1333	455	18	part	part	NOUN
dti-1333	455	19	iii	iii	NOUN
dti-1333	455	20	:	:	PUNCT
dti-1333	455	21	mechanistically	mechanistically	ADV
dti-1333	455	22	defi	defi	VERB
dti-1333	455	23	ning	ne	VERB
dti-1333	455	24	the	the	DET
dti-1333	455	25	role	role	NOUN
dti-1333	455	26	of	of	ADP
dti-1333	455	27	hyperlipidemia	hyperlipidemia	NOUN
dti-1333	455	28	.	.	PUNCT
dti-1333	456	1	j.	j.	PROPN
dti-1333	456	2	lipid	lipid	PROPN
dti-1333	456	3	res	res	PROPN
dti-1333	456	4	.	.	PROPN
dti-1333	456	5	,	,	PUNCT
dti-1333	456	6	46:2037–51	46:2037–51	NUM
dti-1333	456	7	.	.	PUNCT
dti-1333	457	1	steinberg	steinberg	PROPN
dti-1333	457	2	,	,	PUNCT
dti-1333	457	3	d.	d.	PROPN
dti-1333	457	4	2006a	2006a	NUM
dti-1333	457	5	.	.	PUNCT
dti-1333	458	1	the	the	DET
dti-1333	458	2	pathogenesis	pathogenesis	NOUN
dti-1333	458	3	of	of	ADP
dti-1333	458	4	atherosclerosis	atherosclerosis	NOUN
dti-1333	458	5	.	.	PUNCT
dti-1333	459	1	an	an	DET
dti-1333	459	2	interpretive	interpretive	ADJ
dti-1333	459	3	history	history	NOUN
dti-1333	459	4	of	of	ADP
dti-1333	459	5	the	the	DET
dti-1333	459	6	cholesterol	cholesterol	NOUN
dti-1333	459	7	controversy	controversy	NOUN
dti-1333	459	8	,	,	PUNCT
dti-1333	459	9	part	part	NOUN
dti-1333	459	10	iv	iv	ADP
dti-1333	459	11	:	:	PUNCT
dti-1333	459	12	the	the	DET
dti-1333	459	13	1984	1984	NUM
dti-1333	459	14	coronary	coronary	ADJ
dti-1333	459	15	primary	primary	ADJ
dti-1333	459	16	prevention	prevention	NOUN
dti-1333	459	17	trial	trial	NOUN
dti-1333	459	18	ends	end	VERB
dti-1333	459	19	it	it	PRON
dti-1333	459	20	—	—	PUNCT
dti-1333	459	21	almost	almost	ADV
dti-1333	459	22	.	.	PUNCT
dti-1333	460	1	j.	j.	PROPN
dti-1333	460	2	lipid	lipid	PROPN
dti-1333	460	3	res	res	PROPN
dti-1333	460	4	.	.	PROPN
dti-1333	460	5	,	,	PUNCT
dti-1333	460	6	47:1–14	47:1–14	X
dti-1333	460	7	.	.	PUNCT
dti-1333	461	1	steinberg	steinberg	PROPN
dti-1333	461	2	,	,	PUNCT
dti-1333	461	3	d.	d.	PROPN
dti-1333	461	4	2006b	2006b	NUM
dti-1333	461	5	.	.	PUNCT
dti-1333	462	1	thematic	thematic	ADJ
dti-1333	462	2	review	review	NOUN
dti-1333	462	3	series	series	NOUN
dti-1333	462	4	:	:	PUNCT
dti-1333	462	5	the	the	DET
dti-1333	462	6	pathogenesis	pathogenesis	NOUN
dti-1333	462	7	of	of	ADP
dti-1333	462	8	atherosclerosis	atherosclerosis	NOUN
dti-1333	462	9	.	.	PUNCT
dti-1333	463	1	an	an	DET
dti-1333	463	2	interpretive	interpretive	ADJ
dti-1333	463	3	history	history	NOUN
dti-1333	463	4	of	of	ADP
dti-1333	463	5	the	the	DET
dti-1333	463	6	cholesterol	cholesterol	NOUN
dti-1333	463	7	controversy	controversy	NOUN
dti-1333	463	8	,	,	PUNCT
dti-1333	463	9	part	part	NOUN
dti-1333	463	10	v	v	NOUN
dti-1333	463	11	:	:	PUNCT
dti-1333	463	12	the	the	DET
dti-1333	463	13	discovery	discovery	NOUN
dti-1333	463	14	of	of	ADP
dti-1333	463	15	the	the	DET
dti-1333	463	16	statins	statin	NOUN
dti-1333	463	17	and	and	CCONJ
dti-1333	463	18	the	the	DET
dti-1333	463	19	end	end	NOUN
dti-1333	463	20	of	of	ADP
dti-1333	463	21	the	the	DET
dti-1333	463	22	controversy	controversy	NOUN
dti-1333	463	23	.	.	PUNCT
dti-1333	464	1	j.	j.	PROPN
dti-1333	464	2	lipid	lipid	PROPN
dti-1333	464	3	res	res	PROPN
dti-1333	464	4	.	.	PROPN
dti-1333	464	5	,	,	PUNCT
dti-1333	464	6	47:1339–51	47:1339–51	X
dti-1333	464	7	.	.	PUNCT
dti-1333	465	1	tall	tall	ADJ
dti-1333	465	2	,	,	PUNCT
dti-1333	465	3	a.r	a.r	PROPN
dti-1333	465	4	.	.	PROPN
dti-1333	465	5	and	and	CCONJ
dti-1333	465	6	wang	wang	PROPN
dti-1333	465	7	,	,	PUNCT
dti-1333	465	8	n.	n.	PROPN
dti-1333	465	9	2000	2000	NUM
dti-1333	465	10	.	.	PUNCT
dti-1333	466	1	tangier	tangy	ADJ
dti-1333	466	2	disease	disease	NOUN
dti-1333	466	3	as	as	ADP
dti-1333	466	4	a	a	DET
dti-1333	466	5	test	test	NOUN
dti-1333	466	6	of	of	ADP
dti-1333	466	7	the	the	DET
dti-1333	466	8	reverse	reverse	ADJ
dti-1333	466	9	cholesterol	cholesterol	NOUN
dti-1333	466	10	transport	transport	NOUN
dti-1333	466	11	hypothesis	hypothesis	NOUN
dti-1333	466	12	.	.	PUNCT
dti-1333	467	1	j.	j.	PROPN
dti-1333	467	2	clin	clin	PROPN
dti-1333	467	3	.	.	PUNCT
dti-1333	468	1	invest	invest	PROPN
dti-1333	468	2	.	.	PUNCT
dti-1333	469	1	,	,	PUNCT
dti-1333	469	2	106:1205–7	106:1205–7	X
dti-1333	469	3	.	.	PUNCT
dti-1333	470	1	tardif	tardif	PROPN
dti-1333	470	2	,	,	PUNCT
dti-1333	470	3	j.c	j.c	PROPN
dti-1333	470	4	.	.	PROPN
dti-1333	470	5	,	,	PUNCT
dti-1333	470	6	grégoire	grégoire	PROPN
dti-1333	470	7	,	,	PUNCT
dti-1333	470	8	j.	j.	PROPN
dti-1333	470	9	,	,	PUNCT
dti-1333	470	10	l’allier	l’allier	PROPN
dti-1333	470	11	,	,	PUNCT
dti-1333	470	12	p.l	p.l	PROPN
dti-1333	470	13	.	.	PROPN
dti-1333	470	14	et	et	PROPN
dti-1333	470	15	al	al	PROPN
dti-1333	470	16	.	.	PROPN
dti-1333	470	17	2007a	2007a	NOUN
dti-1333	470	18	.	.	PUNCT
dti-1333	471	1	effects	effect	NOUN
dti-1333	471	2	of	of	ADP
dti-1333	471	3	the	the	DET
dti-1333	471	4	antioxidant	antioxidant	ADJ
dti-1333	471	5	succinobucol	succinobucol	NOUN
dti-1333	471	6	(	(	PUNCT
dti-1333	471	7	agi-1067	agi-1067	NOUN
dti-1333	471	8	)	)	PUNCT
dti-1333	471	9	on	on	ADP
dti-1333	471	10	human	human	ADJ
dti-1333	471	11	atherosclerosis	atherosclerosis	NOUN
dti-1333	471	12	in	in	ADP
dti-1333	471	13	a	a	DET
dti-1333	471	14	randomized	randomized	ADJ
dti-1333	471	15	clinical	clinical	ADJ
dti-1333	471	16	trial	trial	NOUN
dti-1333	471	17	.	.	PUNCT
dti-1333	472	1	atherosclerosis	atherosclerosis	NOUN
dti-1333	472	2	,	,	PUNCT
dti-1333	472	3	in	in	ADP
dti-1333	472	4	press	press	NOUN
dti-1333	472	5	.	.	PUNCT
dti-1333	473	1	tardif	tardif	PROPN
dti-1333	473	2	,	,	PUNCT
dti-1333	473	3	j.c	j.c	PROPN
dti-1333	473	4	.	.	PROPN
dti-1333	473	5	,	,	PUNCT
dti-1333	473	6	grégoire	grégoire	PROPN
dti-1333	473	7	,	,	PUNCT
dti-1333	473	8	j.	j.	PROPN
dti-1333	473	9	,	,	PUNCT
dti-1333	473	10	l’allier	l’allier	PROPN
dti-1333	473	11	,	,	PUNCT
dti-1333	473	12	p.l	p.l	PROPN
dti-1333	473	13	.	.	PROPN
dti-1333	473	14	et	et	PROPN
dti-1333	473	15	al	al	PROPN
dti-1333	473	16	.	.	PROPN
dti-1333	473	17	2007b	2007b	NUM
dti-1333	473	18	.	.	PUNCT
dti-1333	474	1	effect	effect	NOUN
dti-1333	474	2	of	of	ADP
dti-1333	474	3	rhdl	rhdl	NOUN
dti-1333	474	4	on	on	ADP
dti-1333	474	5	atherosclerosis	atherosclerosis	NOUN
dti-1333	474	6	-	-	PUNCT
dti-1333	474	7	safety	safety	NOUN
dti-1333	474	8	and	and	CCONJ
dti-1333	474	9	effi	effi	PROPN
dti-1333	474	10	cacy	cacy	PROPN
dti-1333	474	11	(	(	PUNCT
dti-1333	474	12	erase	erase	NOUN
dti-1333	474	13	)	)	PUNCT
dti-1333	474	14	investigators	investigator	NOUN
dti-1333	474	15	.	.	PUNCT
dti-1333	475	1	effects	effect	NOUN
dti-1333	475	2	of	of	ADP
dti-1333	475	3	reconstituted	reconstitute	VERB
dti-1333	475	4	high	high	ADJ
dti-1333	475	5	-	-	PUNCT
dti-1333	475	6	density	density	NOUN
dti-1333	475	7	lipoprotein	lipoprotein	ADJ
dti-1333	475	8	infusions	infusion	NOUN
dti-1333	475	9	on	on	ADP
dti-1333	475	10	coronary	coronary	ADJ
dti-1333	475	11	atherosclerosis	atherosclerosis	NOUN
dti-1333	475	12	:	:	PUNCT
dti-1333	475	13	a	a	DET
dti-1333	475	14	randomized	randomized	ADJ
dti-1333	475	15	controlled	control	VERB
dti-1333	475	16	trial	trial	NOUN
dti-1333	475	17	.	.	PUNCT
dti-1333	476	1	jama	jama	PROPN
dti-1333	476	2	,	,	PUNCT
dti-1333	476	3	297:1675–82	297:1675–82	PROPN
dti-1333	476	4	.	.	PROPN
dti-1333	476	5	54	54	NUM
dti-1333	476	6	brown	brown	ADJ
dti-1333	476	7	and	and	CCONJ
dti-1333	476	8	chiacchia	chiacchia	PROPN
dti-1333	476	9	drug	drug	NOUN
dti-1333	476	10	target	target	NOUN
dti-1333	476	11	insights	insight	NOUN
dti-1333	476	12	2008:3	2008:3	NUM
dti-1333	476	13	toth	toth	PROPN
dti-1333	476	14	,	,	PUNCT
dti-1333	476	15	p.p	p.p	PROPN
dti-1333	476	16	.	.	PROPN
dti-1333	476	17	2007	2007	NUM
dti-1333	476	18	.	.	PUNCT
dti-1333	477	1	reducing	reduce	VERB
dti-1333	477	2	cardiovascular	cardiovascular	ADJ
dti-1333	477	3	risk	risk	NOUN
dti-1333	477	4	by	by	ADP
dti-1333	477	5	targeting	target	VERB
dti-1333	477	6	high	high	ADJ
dti-1333	477	7	-	-	PUNCT
dti-1333	477	8	density	density	NOUN
dti-1333	477	9	lipoprotein	lipoprotein	ADJ
dti-1333	477	10	cholesterol	cholesterol	NOUN
dti-1333	477	11	.	.	PUNCT
dti-1333	478	1	curr	curr	PROPN
dti-1333	478	2	.	.	PUNCT
dti-1333	478	3	atheroscler	atheroscler	PROPN
dti-1333	478	4	.	.	PUNCT
dti-1333	479	1	rep	rep	PROPN
dti-1333	479	2	.	.	PROPN
dti-1333	479	3	,	,	PUNCT
dti-1333	479	4	9:81–8	9:81–8	NUM
dti-1333	479	5	.	.	PUNCT
dti-1333	480	1	van	van	PROPN
dti-1333	480	2	der	der	PROPN
dti-1333	480	3	steeg	steeg	PROPN
dti-1333	480	4	,	,	PUNCT
dti-1333	480	5	w.a	w.a	PROPN
dti-1333	480	6	.	.	PROPN
dti-1333	480	7	,	,	PUNCT
dti-1333	480	8	el	el	PROPN
dti-1333	480	9	-	-	PUNCT
dti-1333	480	10	harchaoui	harchaoui	PROPN
dti-1333	480	11	,	,	PUNCT
dti-1333	480	12	k.	k.	PROPN
dti-1333	480	13	,	,	PUNCT
dti-1333	480	14	kuivenhoven	kuivenhoven	PROPN
dti-1333	480	15	,	,	PUNCT
dti-1333	480	16	j.a	j.a	PROPN
dti-1333	480	17	.	.	PROPN
dti-1333	480	18	et	et	PROPN
dti-1333	480	19	al	al	PROPN
dti-1333	480	20	.	.	PROPN
dti-1333	480	21	2005	2005	NUM
dti-1333	480	22	.	.	PUNCT
dti-1333	481	1	increasing	increase	VERB
dti-1333	481	2	high	high	ADJ
dti-1333	481	3	-	-	PUNCT
dti-1333	481	4	density	density	NOUN
dti-1333	481	5	lipoprotein	lipoprotein	ADJ
dti-1333	481	6	cholesterol	cholesterol	NOUN
dti-1333	481	7	through	through	ADP
dti-1333	481	8	cholesteryl	cholesteryl	NOUN
dti-1333	481	9	ester	ester	NOUN
dti-1333	481	10	transfer	transfer	NOUN
dti-1333	481	11	protein	protein	NOUN
dti-1333	481	12	inhibition	inhibition	NOUN
dti-1333	481	13	:	:	PUNCT
dti-1333	481	14	a	a	DET
dti-1333	481	15	next	next	ADJ
dti-1333	481	16	step	step	NOUN
dti-1333	481	17	in	in	ADP
dti-1333	481	18	the	the	DET
dti-1333	481	19	fi	fi	NOUN
dti-1333	481	20	ght	ght	X
dti-1333	481	21	against	against	ADP
dti-1333	481	22	cardiovascular	cardiovascular	ADJ
dti-1333	481	23	disease	disease	NOUN
dti-1333	481	24	?	?	PUNCT
dti-1333	482	1	curr	curr	PROPN
dti-1333	482	2	.	.	PUNCT
dti-1333	482	3	drug	drug	NOUN
dti-1333	482	4	targets	target	NOUN
dti-1333	482	5	cardiovasc	cardiovasc	PROPN
dti-1333	482	6	.	.	PUNCT
dti-1333	483	1	haematol	haematol	PROPN
dti-1333	483	2	.	.	PUNCT
dti-1333	484	1	disord	disord	PROPN
dti-1333	484	2	.	.	PUNCT
dti-1333	484	3	,	,	PUNCT
dti-1333	485	1	5:481–8	5:481–8	X
dti-1333	485	2	.	.	PUNCT
dti-1333	486	1	vega	vega	PROPN
dti-1333	486	2	,	,	PUNCT
dti-1333	486	3	g.l	g.l	PROPN
dti-1333	486	4	.	.	PROPN
dti-1333	486	5	and	and	CCONJ
dti-1333	486	6	grundy	grundy	PROPN
dti-1333	486	7	,	,	PUNCT
dti-1333	486	8	s.m	s.m	PROPN
dti-1333	486	9	.	.	PROPN
dti-1333	486	10	1996	1996	NUM
dti-1333	486	11	.	.	PUNCT
dti-1333	487	1	hypoalphalipoproteinemia	hypoalphalipoproteinemia	NOUN
dti-1333	487	2	(	(	PUNCT
dti-1333	487	3	low	low	ADJ
dti-1333	487	4	high	high	ADJ
dti-1333	487	5	density	density	NOUN
dti-1333	487	6	lipoprotein	lipoprotein	ADJ
dti-1333	487	7	)	)	PUNCT
dti-1333	487	8	as	as	ADP
dti-1333	487	9	a	a	DET
dti-1333	487	10	risk	risk	NOUN
dti-1333	487	11	factor	factor	NOUN
dti-1333	487	12	for	for	ADP
dti-1333	487	13	coronary	coronary	ADJ
dti-1333	487	14	heart	heart	NOUN
dti-1333	487	15	disease	disease	NOUN
dti-1333	487	16	.	.	PUNCT
dti-1333	488	1	curr	curr	PROPN
dti-1333	488	2	.	.	PUNCT
dti-1333	489	1	opin	opin	NOUN
dti-1333	489	2	.	.	PUNCT
dti-1333	490	1	lipidol	lipidol	PROPN
dti-1333	490	2	.	.	PUNCT
dti-1333	491	1	,	,	PUNCT
dti-1333	491	2	7:209–16	7:209–16	PROPN
dti-1333	491	3	.	.	PUNCT
dti-1333	492	1	verschuren	verschuren	PROPN
dti-1333	492	2	,	,	PUNCT
dti-1333	492	3	w.m	w.m	PROPN
dti-1333	492	4	.	.	PROPN
dti-1333	492	5	,	,	PUNCT
dti-1333	492	6	jacobs	jacobs	PROPN
dti-1333	492	7	,	,	PUNCT
dti-1333	492	8	d.r	d.r	PROPN
dti-1333	492	9	.	.	PROPN
dti-1333	492	10	,	,	PUNCT
dti-1333	492	11	bloemberg	bloemberg	PROPN
dti-1333	492	12	,	,	PUNCT
dti-1333	492	13	b.p	b.p	PROPN
dti-1333	492	14	.	.	PROPN
dti-1333	492	15	et	et	PROPN
dti-1333	492	16	al	al	PROPN
dti-1333	492	17	.	.	PROPN
dti-1333	492	18	1995	1995	NUM
dti-1333	492	19	.	.	PUNCT
dti-1333	493	1	serum	serum	NOUN
dti-1333	493	2	total	total	ADJ
dti-1333	493	3	cholesterol	cholesterol	NOUN
dti-1333	493	4	and	and	CCONJ
dti-1333	493	5	long	long	ADJ
dti-1333	493	6	-	-	PUNCT
dti-1333	493	7	term	term	NOUN
dti-1333	493	8	coronary	coronary	ADJ
dti-1333	493	9	heart	heart	NOUN
dti-1333	493	10	disease	disease	NOUN
dti-1333	493	11	mortality	mortality	NOUN
dti-1333	493	12	in	in	ADP
dti-1333	493	13	different	different	ADJ
dti-1333	493	14	cultures	culture	NOUN
dti-1333	493	15	.	.	PUNCT
dti-1333	494	1	twenty	twenty	NUM
dti-1333	494	2	-	-	PUNCT
dti-1333	494	3	fi	fi	NOUN
dti-1333	494	4	ve	ve	NOUN
dti-1333	494	5	-	-	PUNCT
dti-1333	494	6	year	year	NOUN
dti-1333	494	7	follow	follow	NOUN
dti-1333	494	8	-	-	PUNCT
dti-1333	494	9	up	up	NOUN
dti-1333	494	10	of	of	ADP
dti-1333	494	11	the	the	DET
dti-1333	494	12	seven	seven	NUM
dti-1333	494	13	countries	country	NOUN
dti-1333	494	14	study	study	NOUN
dti-1333	494	15	.	.	PUNCT
dti-1333	495	1	jama	jama	PROPN
dti-1333	495	2	,	,	PUNCT
dti-1333	495	3	274:131–6	274:131–6	NUM
dti-1333	495	4	.	.	PUNCT
dti-1333	496	1	von	von	PROPN
dti-1333	496	2	eckardstein	eckardstein	PROPN
dti-1333	496	3	,	,	PUNCT
dti-1333	496	4	a.	a.	NOUN
dti-1333	496	5	and	and	CCONJ
dti-1333	496	6	assmann	assmann	PROPN
dti-1333	496	7	,	,	PUNCT
dti-1333	496	8	g.	g.	PROPN
dti-1333	496	9	1998	1998	NUM
dti-1333	496	10	.	.	PUNCT
dti-1333	497	1	high	high	ADJ
dti-1333	497	2	density	density	NOUN
dti-1333	497	3	lipoproteins	lipoprotein	NOUN
dti-1333	497	4	and	and	CCONJ
dti-1333	497	5	reverse	reverse	VERB
dti-1333	497	6	cholesterol	cholesterol	NOUN
dti-1333	497	7	transport	transport	NOUN
dti-1333	497	8	:	:	PUNCT
dti-1333	497	9	lessons	lesson	NOUN
dti-1333	497	10	from	from	ADP
dti-1333	497	11	mutations	mutation	NOUN
dti-1333	497	12	.	.	PUNCT
dti-1333	498	1	atherosclerosis	atherosclerosis	NOUN
dti-1333	498	2	,	,	PUNCT
dti-1333	498	3	137(suppl):s7–11	137(suppl):s7–11	NUM
dti-1333	498	4	.	.	PUNCT
dti-1333	499	1	vu	vu	PROPN
dti-1333	499	2	-	-	PUNCT
dti-1333	499	3	dac	dac	PROPN
dti-1333	499	4	,	,	PUNCT
dti-1333	499	5	n.	n.	NOUN
dti-1333	499	6	,	,	PUNCT
dti-1333	499	7	schoonjans	schoonjan	NOUN
dti-1333	499	8	,	,	PUNCT
dti-1333	499	9	k.	k.	PROPN
dti-1333	499	10	,	,	PUNCT
dti-1333	499	11	laine	laine	PROPN
dti-1333	499	12	,	,	PUNCT
dti-1333	499	13	b.	b.	PROPN
dti-1333	499	14	et	et	PROPN
dti-1333	499	15	al	al	PROPN
dti-1333	499	16	.	.	PROPN
dti-1333	499	17	1994	1994	NUM
dti-1333	499	18	.	.	PUNCT
dti-1333	500	1	negative	negative	ADJ
dti-1333	500	2	regulation	regulation	NOUN
dti-1333	500	3	of	of	ADP
dti-1333	500	4	the	the	DET
dti-1333	500	5	human	human	NOUN
dti-1333	500	6	apolipoprotein	apolipoprotein	VERB
dti-1333	500	7	a	a	PROPN
dti-1333	500	8	-	-	PUNCT
dti-1333	500	9	i	i	NOUN
dti-1333	500	10	promoter	promoter	NOUN
dti-1333	500	11	by	by	ADP
dti-1333	500	12	fi	fi	NOUN
dti-1333	500	13	brates	brate	NOUN
dti-1333	500	14	can	can	AUX
dti-1333	500	15	be	be	AUX
dti-1333	500	16	attenuated	attenuate	VERB
dti-1333	500	17	by	by	ADP
dti-1333	500	18	the	the	DET
dti-1333	500	19	interaction	interaction	NOUN
dti-1333	500	20	of	of	ADP
dti-1333	500	21	the	the	DET
dti-1333	500	22	peroxisome	peroxisome	PROPN
dti-1333	500	23	proliferator	proliferator	NOUN
dti-1333	500	24	-	-	PUNCT
dti-1333	500	25	activated	activate	VERB
dti-1333	500	26	receptor	receptor	NOUN
dti-1333	500	27	with	with	ADP
dti-1333	500	28	its	its	PRON
dti-1333	500	29	response	response	NOUN
dti-1333	500	30	element	element	NOUN
dti-1333	500	31	.	.	PUNCT
dti-1333	501	1	j.	j.	PROPN
dti-1333	501	2	biol	biol	PROPN
dti-1333	501	3	.	.	PUNCT
dti-1333	502	1	chem	chem	PROPN
dti-1333	502	2	.	.	PUNCT
dti-1333	502	3	,	,	PUNCT
dti-1333	502	4	269:31012–8	269:31012–8	X
dti-1333	502	5	.	.	PUNCT
dti-1333	503	1	walldius	walldius	PROPN
dti-1333	503	2	,	,	PUNCT
dti-1333	503	3	g.	g.	PROPN
dti-1333	503	4	,	,	PUNCT
dti-1333	503	5	jungner	jungner	PROPN
dti-1333	503	6	,	,	PUNCT
dti-1333	503	7	i.	i.	PROPN
dti-1333	503	8	,	,	PUNCT
dti-1333	503	9	holme	holme	PROPN
dti-1333	503	10	,	,	PUNCT
dti-1333	503	11	i.	i.	PROPN
dti-1333	503	12	et	et	PROPN
dti-1333	503	13	al	al	PROPN
dti-1333	503	14	.	.	PROPN
dti-1333	503	15	2001	2001	NUM
dti-1333	503	16	.	.	PUNCT
dti-1333	504	1	high	high	PROPN
dti-1333	504	2	apolipoprotein	apolipoprotein	PROPN
dti-1333	504	3	b.	b.	PROPN
dti-1333	504	4	,	,	PUNCT
dti-1333	504	5	low	low	ADJ
dti-1333	504	6	apolipoprotein	apolipoprotein	VERB
dti-1333	504	7	a	a	PROPN
dti-1333	504	8	-	-	PUNCT
dti-1333	504	9	i	i	NOUN
dti-1333	504	10	,	,	PUNCT
dti-1333	504	11	and	and	CCONJ
dti-1333	504	12	improvement	improvement	NOUN
dti-1333	504	13	in	in	ADP
dti-1333	504	14	the	the	DET
dti-1333	504	15	prediction	prediction	NOUN
dti-1333	504	16	of	of	ADP
dti-1333	504	17	fatal	fatal	ADJ
dti-1333	504	18	myocardial	myocardial	ADJ
dti-1333	504	19	infarction	infarction	NOUN
dti-1333	504	20	(	(	PUNCT
dti-1333	504	21	amoris	amoris	PROPN
dti-1333	504	22	study	study	NOUN
dti-1333	504	23	):	):	PUNCT
dti-1333	504	24	a	a	DET
dti-1333	504	25	prospective	prospective	ADJ
dti-1333	504	26	study	study	NOUN
dti-1333	504	27	.	.	PUNCT
dti-1333	505	1	lancet	lancet	NOUN
dti-1333	505	2	,	,	PUNCT
dti-1333	505	3	358:2026–33	358:2026–33	PROPN
dti-1333	505	4	.	.	PUNCT
dti-1333	506	1	walsh	walsh	PROPN
dti-1333	506	2	,	,	PUNCT
dti-1333	506	3	a.	a.	PROPN
dti-1333	506	4	,	,	PUNCT
dti-1333	506	5	azrolan	azrolan	ADJ
dti-1333	506	6	,	,	PUNCT
dti-1333	506	7	n.	n.	PROPN
dti-1333	506	8	,	,	PUNCT
dti-1333	506	9	wang	wang	PROPN
dti-1333	506	10	,	,	PUNCT
dti-1333	506	11	k.	k.	PROPN
dti-1333	506	12	et	et	PROPN
dti-1333	506	13	al	al	PROPN
dti-1333	506	14	.	.	PROPN
dti-1333	506	15	1993	1993	NUM
dti-1333	506	16	.	.	PUNCT
dti-1333	507	1	intestinal	intestinal	ADJ
dti-1333	507	2	expression	expression	NOUN
dti-1333	507	3	of	of	ADP
dti-1333	507	4	the	the	DET
dti-1333	507	5	human	human	ADJ
dti-1333	507	6	apoa	apoa	PROPN
dti-1333	507	7	-	-	PUNCT
dti-1333	507	8	i	i	PRON
dti-1333	507	9	gene	gene	NOUN
dti-1333	507	10	in	in	ADP
dti-1333	507	11	transgenic	transgenic	NOUN
dti-1333	507	12	mice	mouse	NOUN
dti-1333	507	13	is	be	AUX
dti-1333	507	14	controlled	control	VERB
dti-1333	507	15	by	by	ADP
dti-1333	507	16	a	a	DET
dti-1333	507	17	dna	dna	PROPN
dti-1333	507	18	region	region	NOUN
dti-1333	507	19	3	3	NUM
dti-1333	507	20	’	'	PUNCT
dti-1333	507	21	to	to	ADP
dti-1333	507	22	the	the	DET
dti-1333	507	23	gene	gene	NOUN
dti-1333	507	24	in	in	ADP
dti-1333	507	25	the	the	DET
dti-1333	507	26	promoter	promoter	NOUN
dti-1333	507	27	of	of	ADP
dti-1333	507	28	the	the	DET
dti-1333	507	29	adjacent	adjacent	ADJ
dti-1333	507	30	convergently	convergently	ADV
dti-1333	507	31	transcribed	transcribe	VERB
dti-1333	507	32	apoc	apoc	PROPN
dti-1333	507	33	-	-	PUNCT
dti-1333	507	34	iii	iii	NUM
dti-1333	507	35	gene	gene	NOUN
dti-1333	507	36	.	.	PUNCT
dti-1333	508	1	j.	j.	PROPN
dti-1333	508	2	lipid	lipid	PROPN
dti-1333	508	3	res	res	PROPN
dti-1333	508	4	.	.	PROPN
dti-1333	508	5	,	,	PUNCT
dti-1333	508	6	34:617–23	34:617–23	NOUN
dti-1333	508	7	.	.	PUNCT
dti-1333	509	1	wang	wang	PROPN
dti-1333	509	2	,	,	PUNCT
dti-1333	509	3	j.	j.	PROPN
dti-1333	509	4	,	,	PUNCT
dti-1333	509	5	burnett	burnett	PROPN
dti-1333	509	6	,	,	PUNCT
dti-1333	509	7	j.r	j.r	PROPN
dti-1333	509	8	.	.	PROPN
dti-1333	509	9	,	,	PUNCT
dti-1333	509	10	near	near	ADV
dti-1333	509	11	,	,	PUNCT
dti-1333	509	12	s.	s.	PROPN
dti-1333	509	13	et	et	PROPN
dti-1333	509	14	al	al	PROPN
dti-1333	509	15	.	.	PROPN
dti-1333	509	16	2000	2000	NUM
dti-1333	509	17	.	.	PUNCT
dti-1333	510	1	common	common	ADJ
dti-1333	510	2	and	and	CCONJ
dti-1333	510	3	rare	rare	ADJ
dti-1333	510	4	abca1	abca1	NOUN
dti-1333	510	5	variants	variant	NOUN
dti-1333	510	6	affecting	affect	VERB
dti-1333	510	7	plasma	plasma	NOUN
dti-1333	510	8	hdl	hdl	PROPN
dti-1333	510	9	cholesterol	cholesterol	PROPN
dti-1333	510	10	.	.	PUNCT
dti-1333	511	1	arterioscler	arterioscler	PROPN
dti-1333	511	2	.	.	PUNCT
dti-1333	512	1	thromb	thromb	PROPN
dti-1333	512	2	.	.	PUNCT
dti-1333	513	1	vasc	vasc	PROPN
dti-1333	513	2	.	.	PUNCT
dti-1333	514	1	biol	biol	PROPN
dti-1333	514	2	.	.	PUNCT
dti-1333	514	3	,	,	PUNCT
dti-1333	514	4	20:1983–9	20:1983–9	NUM
dti-1333	514	5	.	.	PUNCT
dti-1333	515	1	wang	wang	PROPN
dti-1333	515	2	,	,	PUNCT
dti-1333	515	3	z.	z.	PROPN
dti-1333	515	4	,	,	PUNCT
dti-1333	515	5	zou	zou	PROPN
dti-1333	515	6	,	,	PUNCT
dti-1333	515	7	j.	j.	PROPN
dti-1333	515	8	,	,	PUNCT
dti-1333	515	9	cao	cao	PROPN
dti-1333	515	10	,	,	PUNCT
dti-1333	515	11	k.	k.	PROPN
dti-1333	515	12	et	et	PROPN
dti-1333	515	13	al	al	PROPN
dti-1333	515	14	.	.	PROPN
dti-1333	515	15	2005	2005	NUM
dti-1333	515	16	.	.	PUNCT
dti-1333	515	17	dealcoholized	dealcoholize	VERB
dti-1333	515	18	red	red	ADJ
dti-1333	515	19	wine	wine	NOUN
dti-1333	515	20	containing	contain	VERB
dti-1333	515	21	known	know	VERB
dti-1333	515	22	amounts	amount	NOUN
dti-1333	515	23	of	of	ADP
dti-1333	515	24	resveratrol	resveratrol	NOUN
dti-1333	515	25	suppresses	suppress	VERB
dti-1333	515	26	atherosclerosis	atherosclerosis	NOUN
dti-1333	515	27	in	in	ADP
dti-1333	515	28	hypercholesterolemic	hypercholesterolemic	ADJ
dti-1333	515	29	rabbits	rabbit	NOUN
dti-1333	515	30	without	without	ADP
dti-1333	515	31	affecting	affect	VERB
dti-1333	515	32	plasma	plasma	NOUN
dti-1333	515	33	lipid	lipid	NOUN
dti-1333	515	34	levels	level	NOUN
dti-1333	515	35	.	.	PUNCT
dti-1333	516	1	int	int	NOUN
dti-1333	516	2	.	.	PUNCT
dti-1333	517	1	j.	j.	PROPN
dti-1333	517	2	mol	mol	PROPN
dti-1333	517	3	.	.	PROPN
dti-1333	517	4	med	med	PROPN
dti-1333	517	5	.	.	PROPN
dti-1333	517	6	,	,	PUNCT
dti-1333	517	7	16:533–40	16:533–40	PROPN
dti-1333	517	8	.	.	PUNCT
dti-1333	518	1	yamashita	yamashita	PROPN
dti-1333	518	2	,	,	PUNCT
dti-1333	518	3	s.	s.	PROPN
dti-1333	518	4	,	,	PUNCT
dti-1333	518	5	maruyama	maruyama	PROPN
dti-1333	518	6	,	,	PUNCT
dti-1333	518	7	t.	t.	PROPN
dti-1333	518	8	,	,	PUNCT
dti-1333	518	9	hirano	hirano	PROPN
dti-1333	518	10	,	,	PUNCT
dti-1333	518	11	k.	k.	PROPN
dti-1333	518	12	et	et	PROPN
dti-1333	518	13	al	al	PROPN
dti-1333	518	14	.	.	PROPN
dti-1333	518	15	2000	2000	NUM
dti-1333	518	16	.	.	PUNCT
dti-1333	519	1	molecular	molecular	ADJ
dti-1333	519	2	mechanisms	mechanism	NOUN
dti-1333	519	3	,	,	PUNCT
dti-1333	519	4	lipoprotein	lipoprotein	ADJ
dti-1333	519	5	abnormalities	abnormality	NOUN
dti-1333	519	6	and	and	CCONJ
dti-1333	519	7	atherogenicity	atherogenicity	NOUN
dti-1333	519	8	of	of	ADP
dti-1333	519	9	hyperalphalipoproteinemia	hyperalphalipoproteinemia	NOUN
dti-1333	519	10	.	.	PUNCT
dti-1333	520	1	atherosclerosis	atherosclerosis	NOUN
dti-1333	520	2	,	,	PUNCT
dti-1333	520	3	152:271–85	152:271–85	NUM
dti-1333	520	4	.	.	PUNCT
dti-1333	521	1	yusuf	yusuf	PROPN
dti-1333	521	2	,	,	PUNCT
dti-1333	521	3	s.	s.	PROPN
dti-1333	521	4	,	,	PUNCT
dti-1333	521	5	hawken	hawken	PROPN
dti-1333	521	6	,	,	PUNCT
dti-1333	521	7	s.	s.	PROPN
dti-1333	521	8	,	,	PUNCT
dti-1333	521	9	ounpuu	ounpuu	PROPN
dti-1333	521	10	,	,	PUNCT
dti-1333	521	11	s.	s.	PROPN
dti-1333	521	12	et	et	PROPN
dti-1333	521	13	al	al	PROPN
dti-1333	521	14	.	.	PROPN
dti-1333	521	15	2004	2004	NUM
dti-1333	521	16	.	.	PUNCT
dti-1333	522	1	effect	effect	NOUN
dti-1333	522	2	of	of	ADP
dti-1333	522	3	potentially	potentially	ADV
dti-1333	522	4	modifi	modifi	ADJ
dti-1333	522	5	able	able	ADJ
dti-1333	522	6	risk	risk	NOUN
dti-1333	522	7	factors	factor	NOUN
dti-1333	522	8	associated	associate	VERB
dti-1333	522	9	with	with	ADP
dti-1333	522	10	myocardial	myocardial	ADJ
dti-1333	522	11	infarction	infarction	NOUN
dti-1333	522	12	in	in	ADP
dti-1333	522	13	52	52	NUM
dti-1333	522	14	countries	country	NOUN
dti-1333	522	15	(	(	PUNCT
dti-1333	522	16	the	the	DET
dti-1333	522	17	interheart	interheart	NOUN
dti-1333	522	18	study	study	NOUN
dti-1333	522	19	):	):	PUNCT
dti-1333	522	20	case	case	NOUN
dti-1333	522	21	-	-	PUNCT
dti-1333	522	22	control	control	NOUN
dti-1333	522	23	study	study	NOUN
dti-1333	522	24	.	.	PUNCT
dti-1333	523	1	lancet	lancet	PROPN
dti-1333	523	2	,	,	PUNCT
dti-1333	523	3	364:937–52	364:937–52	NUM
dti-1333	523	4	.	.	PUNCT
dti-1333	524	1	zannis	zannis	PROPN
dti-1333	524	2	,	,	PUNCT
dti-1333	524	3	v.i	v.i	PROPN
dti-1333	524	4	.	.	PROPN
dti-1333	524	5	,	,	PUNCT
dti-1333	524	6	kan	kan	PROPN
dti-1333	524	7	,	,	PUNCT
dti-1333	524	8	h.y	h.y	PROPN
dti-1333	524	9	.	.	PROPN
dti-1333	524	10	,	,	PUNCT
dti-1333	524	11	kritis	kritis	PROPN
dti-1333	524	12	,	,	PUNCT
dti-1333	524	13	a.	a.	NOUN
dti-1333	524	14	et	et	PROPN
dti-1333	524	15	al	al	PROPN
dti-1333	524	16	.	.	PROPN
dti-1333	524	17	2001	2001	NUM
dti-1333	524	18	.	.	PUNCT
dti-1333	525	1	transcriptional	transcriptional	ADJ
dti-1333	525	2	regulatory	regulatory	ADJ
dti-1333	525	3	mechanisms	mechanism	NOUN
dti-1333	525	4	of	of	ADP
dti-1333	525	5	the	the	DET
dti-1333	525	6	human	human	ADJ
dti-1333	525	7	apolipoprotein	apolipoprotein	ADJ
dti-1333	525	8	genes	gene	NOUN
dti-1333	525	9	in	in	ADP
dti-1333	525	10	vitro	vitro	X
dti-1333	525	11	and	and	CCONJ
dti-1333	525	12	in	in	ADP
dti-1333	525	13	vivo	vivo	NOUN
dti-1333	525	14	.	.	PUNCT
dti-1333	526	1	curr	curr	PROPN
dti-1333	526	2	.	.	PUNCT
dti-1333	527	1	opin	opin	NOUN
dti-1333	527	2	.	.	PUNCT
dti-1333	528	1	lipidol	lipidol	PROPN
dti-1333	528	2	.	.	PUNCT
dti-1333	528	3	,	,	PUNCT
dti-1333	528	4	12:181–207	12:181–207	NUM
dti-1333	528	5	.	.	PUNCT
dti-1333	529	1	zern	zern	PROPN
dti-1333	529	2	,	,	PUNCT
dti-1333	529	3	t.l	t.l	PROPN
dti-1333	529	4	.	.	PROPN
dti-1333	529	5	and	and	CCONJ
dti-1333	529	6	fernandez	fernandez	PROPN
dti-1333	529	7	,	,	PUNCT
dti-1333	529	8	m.l	m.l	PROPN
dti-1333	529	9	.	.	PROPN
dti-1333	529	10	2005	2005	NUM
dti-1333	529	11	.	.	PUNCT
dti-1333	530	1	cardioprotective	cardioprotective	ADJ
dti-1333	530	2	effects	effect	NOUN
dti-1333	530	3	of	of	ADP
dti-1333	530	4	dietary	dietary	ADJ
dti-1333	530	5	polyphenols	polyphenol	NOUN
dti-1333	530	6	.	.	PUNCT
dti-1333	531	1	j.	j.	PROPN
dti-1333	531	2	nutr	nutr	PROPN
dti-1333	531	3	.	.	PROPN
dti-1333	531	4	,	,	PUNCT
dti-1333	531	5	135:2291–4	135:2291–4	NUM
dti-1333	531	6	.	.	PUNCT
dti-1333	532	1	<	<	X
dti-1333	532	2	<	<	X
dti-1333	532	3	/ascii85encodepages	/ascii85encodepage	NOUN
dti-1333	532	4	false	false	ADJ
dti-1333	532	5	/allowtransparency	/allowtransparency	NOUN
dti-1333	532	6	false	false	ADJ
dti-1333	532	7	/autopositionepsfiles	/autopositionepsfile	NOUN
dti-1333	532	8	true	true	ADJ
dti-1333	532	9	/autorotatepages	/autorotatepage	NOUN
dti-1333	532	10	/none	/none	PUNCT
dti-1333	532	11	/binding	/binding	PUNCT
dti-1333	532	12	/left	/left	ADJ
dti-1333	533	1	/calgrayprofile	/calgrayprofile	VERB
dti-1333	533	2	(	(	PUNCT
dti-1333	533	3	dot	dot	NOUN
dti-1333	533	4	gain	gain	NOUN
dti-1333	533	5	20	20	NUM
dti-1333	533	6	%	%	NOUN
dti-1333	533	7	)	)	PUNCT
dti-1333	533	8	/calrgbprofile	/calrgbprofile	PUNCT
dti-1333	534	1	(	(	PUNCT
dti-1333	534	2	srgb	srgb	PROPN
dti-1333	534	3	iec61966	iec61966	NOUN
dti-1333	534	4	-	-	PUNCT
dti-1333	534	5	2.1	2.1	NUM
dti-1333	534	6	)	)	PUNCT
dti-1333	534	7	/calcmykprofile	/calcmykprofile	PUNCT
dti-1333	535	1	(	(	PUNCT
dti-1333	535	2	u.s	u.s	PROPN
dti-1333	535	3	.	.	PROPN
dti-1333	535	4	web	web	NOUN
dti-1333	535	5	coated	coat	VERB
dti-1333	535	6	\050swop\051	\050swop\051	ADJ
dti-1333	535	7	v2	v2	NOUN
dti-1333	535	8	)	)	PUNCT
dti-1333	535	9	/srgbprofile	/srgbprofile	PUNCT
dti-1333	535	10	(	(	PUNCT
dti-1333	535	11	srgb	srgb	PROPN
dti-1333	535	12	iec61966	iec61966	NOUN
dti-1333	535	13	-	-	PUNCT
dti-1333	535	14	2.1	2.1	NUM
dti-1333	535	15	)	)	PUNCT
dti-1333	535	16	/cannotembedfontpolicy	/cannotembedfontpolicy	PUNCT
dti-1333	536	1	/error	/error	INTJ
dti-1333	536	2	/compatibilitylevel	/compatibilitylevel	NOUN
dti-1333	537	1	1.4	1.4	NUM
dti-1333	537	2	/compressobjects	/compressobject	NOUN
dti-1333	537	3	/tags	/tag	VERB
dti-1333	537	4	/compresspages	/compresspage	NOUN
dti-1333	537	5	true	true	ADJ
dti-1333	537	6	/convertimagestoindexed	/convertimagestoindexed	ADJ
dti-1333	537	7	true	true	ADJ
dti-1333	537	8	/passthroughjpegimages	/passthroughjpegimage	NOUN
dti-1333	537	9	true	true	ADJ
dti-1333	537	10	/createjdffile	/createjdffile	ADJ
dti-1333	537	11	false	false	ADJ
dti-1333	537	12	/createjobticket	/createjobticket	NOUN
dti-1333	537	13	false	false	ADJ
dti-1333	537	14	/defaultrenderingintent	/defaultrenderingintent	NOUN
dti-1333	537	15	/default	/default	PUNCT
dti-1333	537	16	/detectblends	/detectblend	NOUN
dti-1333	537	17	true	true	ADJ
dti-1333	537	18	/colorconversionstrategy	/colorconversionstrategy	NOUN
dti-1333	537	19	/leavecolorunchanged	/leavecolorunchange	VERB
dti-1333	537	20	/dothumbnails	/dothumbnail	VERB
dti-1333	537	21	false	false	ADJ
dti-1333	537	22	/embedallfonts	/embedallfont	NOUN
dti-1333	537	23	true	true	ADJ
dti-1333	537	24	/embedjoboptions	/embedjoboption	NOUN
dti-1333	537	25	true	true	ADJ
dti-1333	537	26	/dscreportinglevel	/dscreportinglevel	NOUN
dti-1333	537	27	0	0	NUM
dti-1333	537	28	/emitdscwarnings	/emitdscwarning	NOUN
dti-1333	537	29	false	false	ADJ
dti-1333	537	30	/endpage	/endpage	NOUN
dti-1333	537	31	-1	-1	NOUN
dti-1333	537	32	/imagememory	/imagememory	NUM
dti-1333	538	1	1048576	1048576	NUM
dti-1333	538	2	/lockdistillerparams	/lockdistillerparams	NOUN
dti-1333	538	3	false	false	ADJ
dti-1333	538	4	/maxsubsetpct	/maxsubsetpct	ADJ
dti-1333	538	5	100	100	NUM
dti-1333	538	6	/optimize	/optimize	NOUN
dti-1333	538	7	true	true	ADJ
dti-1333	538	8	/opm	/opm	NOUN
dti-1333	538	9	1	1	NUM
dti-1333	538	10	/parsedsccomments	/parsedsccomment	NOUN
dti-1333	538	11	true	true	ADJ
dti-1333	538	12	/parsedsccommentsfordocinfo	/parsedsccommentsfordocinfo	VERB
dti-1333	538	13	true	true	ADJ
dti-1333	538	14	/preservecopypage	/preservecopypage	NOUN
dti-1333	538	15	true	true	ADJ
dti-1333	538	16	/preserveepsinfo	/preserveepsinfo	NOUN
dti-1333	538	17	true	true	ADJ
dti-1333	538	18	/preservehalftoneinfo	/preservehalftoneinfo	PUNCT
dti-1333	538	19	false	false	ADJ
dti-1333	538	20	/preserveopicomments	/preserveopicomment	NOUN
dti-1333	538	21	false	false	ADJ
dti-1333	538	22	/preserveoverprintsettings	/preserveoverprintsetting	NOUN
dti-1333	538	23	true	true	ADJ
dti-1333	538	24	/startpage	/startpage	NOUN
dti-1333	538	25	1	1	NUM
dti-1333	538	26	/subsetfonts	/subsetfont	NOUN
dti-1333	538	27	true	true	ADJ
dti-1333	538	28	/transferfunctioninfo	/transferfunctioninfo	PUNCT
dti-1333	538	29	/apply	/apply	PUNCT
dti-1333	538	30	/ucrandbginfo	/ucrandbginfo	PUNCT
dti-1333	539	1	/preserve	/preserve	NOUN
dti-1333	539	2	/useprologue	/useprologue	NOUN
dti-1333	539	3	false	false	ADJ
dti-1333	539	4	/colorsettingsfile	/colorsettingsfile	NOUN
dti-1333	539	5	(	(	PUNCT
dti-1333	539	6	)	)	PUNCT
dti-1333	539	7	/alwaysembed	/alwaysembe	VERB
dti-1333	539	8	[	[	PUNCT
dti-1333	539	9	true	true	ADJ
dti-1333	539	10	]	]	PUNCT
dti-1333	539	11	/neverembed	/neverembed	PUNCT
dti-1333	540	1	[	[	PUNCT
dti-1333	540	2	true	true	ADJ
dti-1333	540	3	]	]	PUNCT
dti-1333	540	4	/antialiascolorimages	/antialiascolorimages	X
dti-1333	540	5	false	false	ADJ
dti-1333	540	6	/downsamplecolorimages	/downsamplecolorimage	NOUN
dti-1333	540	7	true	true	ADJ
dti-1333	540	8	/colorimagedownsampletype	/colorimagedownsampletype	PUNCT
dti-1333	540	9	/bicubic	/bicubic	NOUN
dti-1333	540	10	/colorimageresolution	/colorimageresolution	NOUN
dti-1333	540	11	300	300	NUM
dti-1333	540	12	/colorimagedepth	/colorimagedepth	PRON
dti-1333	541	1	-1	-1	INTJ
dti-1333	541	2	/colorimagedownsamplethreshold	/colorimagedownsamplethreshold	PUNCT
dti-1333	541	3	1.50000	1.50000	NUM
dti-1333	541	4	/encodecolorimages	/encodecolorimage	NOUN
dti-1333	541	5	true	true	ADJ
dti-1333	541	6	/colorimagefilter	/colorimagefilter	PUNCT
dti-1333	541	7	/dctencode	/dctencode	PUNCT
dti-1333	541	8	/autofiltercolorimages	/autofiltercolorimage	NOUN
dti-1333	541	9	true	true	ADJ
dti-1333	541	10	/colorimageautofilterstrategy	/colorimageautofilterstrategy	PUNCT
dti-1333	541	11	/jpeg	/jpeg	PUNCT
dti-1333	541	12	/coloracsimagedict	/coloracsimagedict	PUNCT
dti-1333	542	1	<	<	X
dti-1333	542	2	<	<	X
dti-1333	542	3	/qfactor	/qfactor	NOUN
dti-1333	542	4	0.15	0.15	NUM
dti-1333	542	5	/hsamples	/hsample	NOUN
dti-1333	543	1	[	[	X
dti-1333	543	2	1	1	NUM
dti-1333	543	3	1	1	NUM
dti-1333	543	4	1	1	NUM
dti-1333	543	5	1	1	NUM
dti-1333	543	6	]	]	PUNCT
dti-1333	543	7	/vsamples	/vsample	NOUN
dti-1333	544	1	[	[	X
dti-1333	544	2	1	1	NUM
dti-1333	544	3	1	1	NUM
dti-1333	544	4	1	1	NUM
dti-1333	544	5	1	1	NUM
dti-1333	544	6	]	]	PUNCT
dti-1333	544	7	>	>	PUNCT
dti-1333	544	8	>	>	X
dti-1333	544	9	/colorimagedict	/colorimagedict	PUNCT
dti-1333	545	1	<	<	X
dti-1333	545	2	<	<	X
dti-1333	545	3	/qfactor	/qfactor	NOUN
dti-1333	545	4	0.15	0.15	NUM
dti-1333	545	5	/hsamples	/hsample	NOUN
dti-1333	546	1	[	[	X
dti-1333	546	2	1	1	NUM
dti-1333	546	3	1	1	NUM
dti-1333	546	4	1	1	NUM
dti-1333	546	5	1	1	NUM
dti-1333	546	6	]	]	PUNCT
dti-1333	546	7	/vsamples	/vsample	NOUN
dti-1333	547	1	[	[	X
dti-1333	547	2	1	1	NUM
dti-1333	547	3	1	1	NUM
dti-1333	547	4	1	1	NUM
dti-1333	547	5	1	1	NUM
dti-1333	547	6	]	]	PUNCT
dti-1333	547	7	>	>	PUNCT
dti-1333	547	8	>	>	X
dti-1333	547	9	/jpeg2000coloracsimagedict	/jpeg2000coloracsimagedict	PUNCT
dti-1333	548	1	<	<	X
dti-1333	548	2	<	<	X
dti-1333	548	3	/tilewidth	/tilewidth	PUNCT
dti-1333	548	4	256	256	NUM
dti-1333	548	5	/tileheight	/tileheight	NUM
dti-1333	548	6	256	256	NUM
dti-1333	548	7	/quality	/quality	NOUN
dti-1333	548	8	30	30	NUM
dti-1333	548	9	>	>	PUNCT
dti-1333	548	10	>	>	X
dti-1333	548	11	/jpeg2000colorimagedict	/jpeg2000colorimagedict	PUNCT
dti-1333	548	12	<	<	X
dti-1333	548	13	<	<	X
dti-1333	548	14	/tilewidth	/tilewidth	PUNCT
dti-1333	548	15	256	256	NUM
dti-1333	548	16	/tileheight	/tileheight	NUM
dti-1333	548	17	256	256	NUM
dti-1333	548	18	/quality	/quality	NOUN
dti-1333	548	19	30	30	NUM
dti-1333	548	20	>	>	PUNCT
dti-1333	548	21	>	>	X
dti-1333	548	22	/antialiasgrayimages	/antialiasgrayimages	X
dti-1333	548	23	false	false	ADJ
dti-1333	548	24	/downsamplegrayimages	/downsamplegrayimage	NOUN
dti-1333	549	1	true	true	ADJ
dti-1333	549	2	/grayimagedownsampletype	/grayimagedownsampletype	NOUN
dti-1333	549	3	/bicubic	/bicubic	NOUN
dti-1333	549	4	/grayimageresolution	/grayimageresolution	NOUN
dti-1333	549	5	300	300	NUM
dti-1333	549	6	/grayimagedepth	/grayimagedepth	PUNCT
dti-1333	549	7	-1	-1	PUNCT
dti-1333	549	8	/grayimagedownsamplethreshold	/grayimagedownsamplethreshold	PRON
dti-1333	550	1	1.50000	1.50000	NUM
dti-1333	550	2	/encodegrayimages	/encodegrayimage	NOUN
dti-1333	550	3	true	true	ADJ
dti-1333	550	4	/grayimagefilter	/grayimagefilter	NOUN
dti-1333	550	5	/dctencode	/dctencode	PUNCT
dti-1333	551	1	/autofiltergrayimages	/autofiltergrayimages	VERB
dti-1333	551	2	true	true	ADJ
dti-1333	551	3	/grayimageautofilterstrategy	/grayimageautofilterstrategy	INTJ
dti-1333	551	4	/jpeg	/jpeg	PUNCT
dti-1333	551	5	/grayacsimagedict	/grayacsimagedict	PUNCT
dti-1333	552	1	<	<	X
dti-1333	552	2	<	<	X
dti-1333	552	3	/qfactor	/qfactor	NOUN
dti-1333	552	4	0.15	0.15	NUM
dti-1333	552	5	/hsamples	/hsample	NOUN
dti-1333	553	1	[	[	X
dti-1333	553	2	1	1	NUM
dti-1333	553	3	1	1	NUM
dti-1333	553	4	1	1	NUM
dti-1333	553	5	1	1	NUM
dti-1333	553	6	]	]	PUNCT
dti-1333	553	7	/vsamples	/vsample	NOUN
dti-1333	554	1	[	[	X
dti-1333	554	2	1	1	NUM
dti-1333	554	3	1	1	NUM
dti-1333	554	4	1	1	NUM
dti-1333	554	5	1	1	NUM
dti-1333	554	6	]	]	PUNCT
dti-1333	554	7	>	>	PUNCT
dti-1333	554	8	>	>	X
dti-1333	554	9	/grayimagedict	/grayimagedict	PUNCT
dti-1333	555	1	<	<	X
dti-1333	555	2	<	<	X
dti-1333	555	3	/qfactor	/qfactor	NOUN
dti-1333	555	4	0.15	0.15	NUM
dti-1333	555	5	/hsamples	/hsample	NOUN
dti-1333	556	1	[	[	X
dti-1333	556	2	1	1	NUM
dti-1333	556	3	1	1	NUM
dti-1333	556	4	1	1	NUM
dti-1333	556	5	1	1	NUM
dti-1333	556	6	]	]	PUNCT
dti-1333	556	7	/vsamples	/vsample	NOUN
dti-1333	557	1	[	[	X
dti-1333	557	2	1	1	NUM
dti-1333	557	3	1	1	NUM
dti-1333	557	4	1	1	NUM
dti-1333	557	5	1	1	NUM
dti-1333	557	6	]	]	PUNCT
dti-1333	557	7	>	>	X
dti-1333	557	8	>	>	X
dti-1333	557	9	/jpeg2000grayacsimagedict	/jpeg2000grayacsimagedict	PUNCT
dti-1333	558	1	<	<	X
dti-1333	558	2	<	<	X
dti-1333	558	3	/tilewidth	/tilewidth	PUNCT
dti-1333	558	4	256	256	NUM
dti-1333	558	5	/tileheight	/tileheight	NUM
dti-1333	558	6	256	256	NUM
dti-1333	558	7	/quality	/quality	NOUN
dti-1333	558	8	30	30	NUM
dti-1333	558	9	>	>	PUNCT
dti-1333	558	10	>	>	X
dti-1333	558	11	/jpeg2000grayimagedict	/jpeg2000grayimagedict	PUNCT
dti-1333	558	12	<	<	X
dti-1333	558	13	<	<	X
dti-1333	558	14	/tilewidth	/tilewidth	PUNCT
dti-1333	558	15	256	256	NUM
dti-1333	558	16	/tileheight	/tileheight	NUM
dti-1333	558	17	256	256	NUM
dti-1333	558	18	/quality	/quality	NOUN
dti-1333	558	19	30	30	NUM
dti-1333	558	20	>	>	PUNCT
dti-1333	558	21	>	>	X
dti-1333	558	22	/antialiasmonoimages	/antialiasmonoimage	NOUN
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dti-1333	571	4	/ita	/ita	PUNCT
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dti-1333	572	7	>	>	X
dti-1333	572	8	/sve	/sve	NOUN
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dti-1333	573	3	>	>	X
dti-1333	573	4	/enu	/enu	PROPN
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dti-1333	573	7	>	>	X
dti-1333	573	8	>	>	X
dti-1333	573	9	>	>	X
dti-1333	573	10	>	>	X
dti-1333	573	11	>	>	X
dti-1333	573	12	setdistillerparams	setdistillerparam	NOUN
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dti-1333	574	3	/hwresolution	/hwresolution	NOUN
dti-1333	575	1	[	[	X
dti-1333	575	2	2400	2400	NUM
dti-1333	575	3	2400	2400	NUM
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dti-1333	575	5	/pagesize	/pagesize	X
dti-1333	576	1	[	[	X
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dti-1333	576	6	>	>	X
dti-1333	576	7	setpagedevice	setpagedevice	PROPN