id	sid	tid	token	lemma	pos
dti-1334	1	1	nemunaitis	nemunaitis	PROPN
dti-1334	1	2	et	et	PROPN
dti-1334	1	3	al.indd	al.indd	X
dti-1334	1	4	drug	drug	NOUN
dti-1334	1	5	target	target	NOUN
dti-1334	1	6	insights	insight	NOUN
dti-1334	1	7	2008:3	2008:3	NUM
dti-1334	1	8	55–66	55–66	NUM
dti-1334	1	9	55	55	NUM
dti-1334	1	10	review	review	NOUN
dti-1334	1	11	correspondence	correspondence	NOUN
dti-1334	1	12	:	:	PUNCT
dti-1334	1	13	john	john	PROPN
dti-1334	1	14	j.	j.	PROPN
dti-1334	1	15	nemunaitis	nemunaitis	PROPN
dti-1334	1	16	,	,	PUNCT
dti-1334	1	17	m.d	m.d	PROPN
dti-1334	1	18	.	.	PROPN
dti-1334	1	19	,	,	PUNCT
dti-1334	1	20	1700	1700	NUM
dti-1334	1	21	pacifi	pacifi	NOUN
dti-1334	1	22	c	c	PROPN
dti-1334	1	23	avenue	avenue	PROPN
dti-1334	1	24	,	,	PUNCT
dti-1334	1	25	suite	suite	NOUN
dti-1334	1	26	1100	1100	NUM
dti-1334	1	27	,	,	PUNCT
dti-1334	1	28	dallas	dallas	PROPN
dti-1334	1	29	,	,	PUNCT
dti-1334	1	30	tx	tx	PROPN
dti-1334	1	31	75201	75201	NUM
dti-1334	1	32	.	.	PUNCT
dti-1334	2	1	tel	tel	ADP
dti-1334	2	2	:	:	PUNCT
dti-1334	2	3	214	214	NUM
dti-1334	2	4	-	-	SYM
dti-1334	2	5	658	658	NUM
dti-1334	2	6	-	-	NUM
dti-1334	2	7	1965	1965	NUM
dti-1334	2	8	;	;	PUNCT
dti-1334	2	9	fax	fax	NOUN
dti-1334	2	10	:	:	PUNCT
dti-1334	2	11	214	214	NUM
dti-1334	2	12	-	-	SYM
dti-1334	2	13	658	658	NUM
dti-1334	2	14	-	-	SYM
dti-1334	2	15	1992	1992	NUM
dti-1334	2	16	;	;	PUNCT
dti-1334	2	17	email	email	NOUN
dti-1334	2	18	:	:	PUNCT
dti-1334	3	1	jnemunaitis@marycrowley.org	jnemunaitis@marycrowley.org	PROPN
dti-1334	3	2	copyright	copyright	NOUN
dti-1334	3	3	in	in	ADP
dti-1334	3	4	this	this	DET
dti-1334	3	5	article	article	NOUN
dti-1334	3	6	,	,	PUNCT
dti-1334	3	7	its	its	PRON
dti-1334	3	8	metadata	metadata	NOUN
dti-1334	3	9	,	,	PUNCT
dti-1334	3	10	and	and	CCONJ
dti-1334	3	11	any	any	DET
dti-1334	3	12	supplementary	supplementary	ADJ
dti-1334	3	13	data	datum	NOUN
dti-1334	3	14	is	be	AUX
dti-1334	3	15	held	hold	VERB
dti-1334	3	16	by	by	ADP
dti-1334	3	17	its	its	PRON
dti-1334	3	18	author	author	NOUN
dti-1334	3	19	or	or	CCONJ
dti-1334	3	20	authors	author	NOUN
dti-1334	3	21	.	.	PUNCT
dti-1334	4	1	it	it	PRON
dti-1334	4	2	is	be	AUX
dti-1334	4	3	published	publish	VERB
dti-1334	4	4	under	under	ADP
dti-1334	4	5	the	the	DET
dti-1334	4	6	creative	creative	ADJ
dti-1334	4	7	commons	common	NOUN
dti-1334	4	8	attribution	attribution	NOUN
dti-1334	4	9	by	by	ADP
dti-1334	4	10	licence	licence	NOUN
dti-1334	4	11	.	.	PUNCT
dti-1334	5	1	for	for	SCONJ
dti-1334	5	2	further	further	ADJ
dti-1334	5	3	information	information	NOUN
dti-1334	5	4	go	go	VERB
dti-1334	5	5	to	to	ADP
dti-1334	5	6	:	:	PUNCT
dti-1334	5	7	http://creativecommons.org/licenses/by/3.0/.	http://creativecommons.org/licenses/by/3.0/.	NOUN
dti-1334	5	8	use	use	NOUN
dti-1334	5	9	of	of	ADP
dti-1334	5	10	proteomics	proteomic	NOUN
dti-1334	5	11	analysis	analysis	NOUN
dti-1334	5	12	for	for	ADP
dti-1334	5	13	molecular	molecular	ADJ
dti-1334	5	14	precision	precision	NOUN
dti-1334	5	15	approaches	approach	NOUN
dti-1334	5	16	in	in	ADP
dti-1334	5	17	cancer	cancer	NOUN
dti-1334	5	18	therapy	therapy	NOUN
dti-1334	5	19	yuqiao	yuqiao	PROPN
dti-1334	5	20	shen1	shen1	PROPN
dti-1334	5	21	,	,	PUNCT
dti-1334	5	22	neil	neil	PROPN
dti-1334	5	23	n.	n.	PROPN
dti-1334	5	24	senzer1,2	senzer1,2	PROPN
dti-1334	5	25	and	and	CCONJ
dti-1334	5	26	john	john	PROPN
dti-1334	5	27	j.	j.	PROPN
dti-1334	6	1	nemunaitis2	nemunaitis2	PROPN
dti-1334	7	1	1lead	1lead	NUM
dti-1334	7	2	therapeutics	therapeutic	NOUN
dti-1334	7	3	,	,	PUNCT
dti-1334	7	4	inc	inc	PROPN
dti-1334	7	5	.	.	PROPN
dti-1334	7	6	,	,	PUNCT
dti-1334	7	7	san	san	PROPN
dti-1334	7	8	bruno	bruno	PROPN
dti-1334	7	9	,	,	PUNCT
dti-1334	7	10	ca	ca	NOUN
dti-1334	7	11	.	.	PUNCT
dti-1334	8	1	2mary	2mary	ADJ
dti-1334	8	2	crowley	crowley	NOUN
dti-1334	8	3	cancer	cancer	NOUN
dti-1334	8	4	research	research	NOUN
dti-1334	8	5	centers	center	NOUN
dti-1334	8	6	,	,	PUNCT
dti-1334	8	7	dallas	dallas	PROPN
dti-1334	8	8	,	,	PUNCT
dti-1334	8	9	tx	tx	PROPN
dti-1334	8	10	.	.	PUNCT
dti-1334	9	1	abstract	abstract	PROPN
dti-1334	9	2	:	:	PUNCT
dti-1334	9	3	the	the	DET
dti-1334	9	4	rapidly	rapidly	ADV
dti-1334	9	5	expanding	expand	VERB
dti-1334	9	6	data	datum	NOUN
dti-1334	9	7	sets	set	NOUN
dti-1334	9	8	derived	derive	VERB
dti-1334	9	9	from	from	ADP
dti-1334	9	10	genomic	genomic	NOUN
dti-1334	9	11	and	and	CCONJ
dti-1334	9	12	transcriptomic	transcriptomic	ADJ
dti-1334	9	13	analyses	analysis	NOUN
dti-1334	9	14	have	have	AUX
dti-1334	9	15	allowed	allow	VERB
dti-1334	9	16	greater	great	ADJ
dti-1334	9	17	understanding	understanding	NOUN
dti-1334	9	18	of	of	ADP
dti-1334	9	19	structural	structural	ADJ
dti-1334	9	20	and	and	CCONJ
dti-1334	9	21	functional	functional	ADJ
dti-1334	9	22	network	network	NOUN
dti-1334	9	23	patterns	pattern	NOUN
dti-1334	9	24	within	within	ADP
dti-1334	9	25	the	the	DET
dti-1334	9	26	genome	genome	NOUN
dti-1334	9	27	resulting	result	VERB
dti-1334	9	28	in	in	ADP
dti-1334	9	29	a	a	DET
dti-1334	9	30	realignment	realignment	NOUN
dti-1334	9	31	of	of	ADP
dti-1334	9	32	thinking	thinking	NOUN
dti-1334	9	33	within	within	ADP
dti-1334	9	34	a	a	DET
dti-1334	9	35	systems	system	NOUN
dti-1334	9	36	biologic	biologic	NOUN
dti-1334	9	37	framework	framework	NOUN
dti-1334	9	38	of	of	ADP
dti-1334	9	39	cancer	cancer	NOUN
dti-1334	9	40	.	.	PUNCT
dti-1334	10	1	however	however	ADV
dti-1334	10	2	,	,	PUNCT
dti-1334	10	3	insofar	insofar	ADV
dti-1334	10	4	as	as	ADV
dti-1334	10	5	spatially	spatially	ADV
dti-1334	10	6	and	and	CCONJ
dti-1334	10	7	temporally	temporally	ADV
dti-1334	10	8	dynamic	dynamic	ADJ
dti-1334	10	9	differential	differential	NOUN
dti-1334	10	10	gene	gene	NOUN
dti-1334	10	11	expression	expression	NOUN
dti-1334	10	12	at	at	ADP
dti-1334	10	13	the	the	DET
dti-1334	10	14	protein	protein	NOUN
dti-1334	10	15	level	level	NOUN
dti-1334	10	16	is	be	AUX
dti-1334	10	17	the	the	DET
dti-1334	10	18	mediate	mediate	ADJ
dti-1334	10	19	effector	effector	NOUN
dti-1334	10	20	of	of	ADP
dti-1334	10	21	cellular	cellular	ADJ
dti-1334	10	22	behavior	behavior	NOUN
dti-1334	10	23	and	and	CCONJ
dti-1334	10	24	,	,	PUNCT
dti-1334	10	25	in	in	ADP
dti-1334	10	26	view	view	NOUN
dti-1334	10	27	of	of	ADP
dti-1334	10	28	extensive	extensive	ADJ
dti-1334	10	29	post	post	ADJ
dti-1334	10	30	translational	translational	ADJ
dti-1334	10	31	modifi	modifi	NOUN
dti-1334	10	32	cation	cation	NOUN
dti-1334	10	33	(	(	PUNCT
dti-1334	10	34	ptm	ptm	PROPN
dti-1334	10	35	)	)	PUNCT
dti-1334	10	36	,	,	PUNCT
dti-1334	10	37	the	the	DET
dti-1334	10	38	need	need	NOUN
dti-1334	10	39	for	for	ADP
dti-1334	10	40	sensitive	sensitive	ADJ
dti-1334	10	41	,	,	PUNCT
dti-1334	10	42	quantitative	quantitative	ADJ
dti-1334	10	43	,	,	PUNCT
dti-1334	10	44	and	and	CCONJ
dti-1334	10	45	high	high	ADJ
dti-1334	10	46	throughput	throughput	NOUN
dti-1334	10	47	proteomic	proteomic	ADJ
dti-1334	10	48	analytic	analytic	ADJ
dti-1334	10	49	techniques	technique	NOUN
dti-1334	10	50	has	have	AUX
dti-1334	10	51	emerged	emerge	VERB
dti-1334	10	52	.	.	PUNCT
dti-1334	11	1	to	to	PART
dti-1334	11	2	circumvent	circumvent	VERB
dti-1334	11	3	the	the	DET
dti-1334	11	4	problems	problem	NOUN
dti-1334	11	5	of	of	ADP
dti-1334	11	6	tissue	tissue	NOUN
dti-1334	11	7	sample	sample	NOUN
dti-1334	11	8	heterogeneity	heterogeneity	NOUN
dti-1334	11	9	,	,	PUNCT
dti-1334	11	10	laser	laser	NOUN
dti-1334	11	11	capture	capture	NOUN
dti-1334	11	12	microdissection	microdissection	NOUN
dti-1334	11	13	(	(	PUNCT
dti-1334	11	14	lcm	lcm	NOUN
dti-1334	11	15	)	)	PUNCT
dti-1334	11	16	allows	allow	VERB
dti-1334	11	17	for	for	ADP
dti-1334	11	18	the	the	DET
dti-1334	11	19	acquisition	acquisition	NOUN
dti-1334	11	20	of	of	ADP
dti-1334	11	21	homogeneous	homogeneous	ADJ
dti-1334	11	22	cell	cell	NOUN
dti-1334	11	23	populations	population	NOUN
dti-1334	11	24	.	.	PUNCT
dti-1334	12	1	using	use	VERB
dti-1334	12	2	different	different	ADJ
dti-1334	12	3	fl	fl	PRON
dti-1334	12	4	uorescent	uorescent	ADJ
dti-1334	12	5	dyes	dye	NOUN
dti-1334	12	6	to	to	PART
dti-1334	12	7	label	label	NOUN
dti-1334	12	8	protein	protein	NOUN
dti-1334	12	9	samples	sample	NOUN
dti-1334	12	10	prior	prior	ADV
dti-1334	12	11	to	to	ADP
dti-1334	12	12	gel	gel	NOUN
dti-1334	12	13	electrophoresis	electrophoresis	NOUN
dti-1334	12	14	,	,	PUNCT
dti-1334	12	15	2	2	NUM
dti-1334	12	16	-	-	SYM
dti-1334	12	17	d	d	PROPN
dti-1334	12	18	dige	dige	NOUN
dti-1334	12	19	(	(	PUNCT
dti-1334	12	20	twodimensional	twodimensional	ADJ
dti-1334	12	21	differential	differential	NOUN
dti-1334	12	22	in	in	ADP
dti-1334	12	23	-	-	PUNCT
dti-1334	12	24	gel	gel	NOUN
dti-1334	12	25	electrophoresis	electrophoresis	NOUN
dti-1334	12	26	)	)	PUNCT
dti-1334	12	27	can	can	AUX
dti-1334	12	28	,	,	PUNCT
dti-1334	12	29	with	with	ADP
dti-1334	12	30	reasonable	reasonable	ADJ
dti-1334	12	31	sensitivity	sensitivity	NOUN
dti-1334	12	32	,	,	PUNCT
dti-1334	12	33	process	process	NOUN
dti-1334	12	34	three	three	NUM
dti-1334	12	35	protein	protein	NOUN
dti-1334	12	36	samples	sample	NOUN
dti-1334	12	37	on	on	ADP
dti-1334	12	38	the	the	DET
dti-1334	12	39	same	same	ADJ
dti-1334	12	40	gel	gel	NOUN
dti-1334	12	41	allowing	allow	VERB
dti-1334	12	42	for	for	ADP
dti-1334	12	43	intragel	intragel	NOUN
dti-1334	12	44	relative	relative	ADJ
dti-1334	12	45	quantifi	quantifi	ADJ
dti-1334	12	46	cation	cation	NOUN
dti-1334	12	47	.	.	PUNCT
dti-1334	13	1	mudpit	mudpit	NOUN
dti-1334	13	2	(	(	PUNCT
dti-1334	13	3	multidimensional	multidimensional	ADJ
dti-1334	13	4	protein	protein	NOUN
dti-1334	13	5	identifi	identifi	PROPN
dti-1334	13	6	cation	cation	NOUN
dti-1334	13	7	technology	technology	NOUN
dti-1334	13	8	)	)	PUNCT
dti-1334	13	9	is	be	AUX
dti-1334	13	10	a	a	DET
dti-1334	13	11	non	non	ADJ
dti-1334	13	12	-	-	ADJ
dti-1334	13	13	gel	gel	ADJ
dti-1334	13	14	approach	approach	NOUN
dti-1334	13	15	exploiting	exploit	VERB
dti-1334	13	16	the	the	DET
dti-1334	13	17	unique	unique	ADJ
dti-1334	13	18	physical	physical	ADJ
dti-1334	13	19	properties	property	NOUN
dti-1334	13	20	of	of	ADP
dti-1334	13	21	charge	charge	NOUN
dti-1334	13	22	and	and	CCONJ
dti-1334	13	23	hydrophobicity	hydrophobicity	NOUN
dti-1334	13	24	which	which	PRON
dti-1334	13	25	allows	allow	VERB
dti-1334	13	26	the	the	DET
dti-1334	13	27	separation	separation	NOUN
dti-1334	13	28	of	of	ADP
dti-1334	13	29	peptide	peptide	ADJ
dti-1334	13	30	mixtures	mixture	NOUN
dti-1334	13	31	as	as	ADV
dti-1334	13	32	well	well	ADV
dti-1334	13	33	as	as	ADP
dti-1334	13	34	direct	direct	ADJ
dti-1334	13	35	ms	ms	NOUN
dti-1334	13	36	(	(	PUNCT
dti-1334	13	37	mass	mass	NOUN
dti-1334	13	38	spectrometry	spectrometry	NOUN
dti-1334	13	39	)	)	PUNCT
dti-1334	13	40	and	and	CCONJ
dti-1334	13	41	database	database	NOUN
dti-1334	13	42	searching	searching	NOUN
dti-1334	13	43	.	.	PUNCT
dti-1334	14	1	the	the	DET
dti-1334	14	2	introduction	introduction	NOUN
dti-1334	14	3	of	of	ADP
dti-1334	14	4	itraq	itraq	PROPN
dti-1334	14	5	(	(	PUNCT
dti-1334	14	6	isobaric	isobaric	ADJ
dti-1334	14	7	tags	tag	NOUN
dti-1334	14	8	for	for	ADP
dti-1334	14	9	relative	relative	ADJ
dti-1334	14	10	and	and	CCONJ
dti-1334	14	11	absolute	absolute	ADJ
dti-1334	14	12	quantifi	quantifi	ADJ
dti-1334	14	13	cation	cation	NOUN
dti-1334	14	14	)	)	PUNCT
dti-1334	14	15	achieves	achieve	VERB
dti-1334	14	16	labeling	labeling	NOUN
dti-1334	14	17	of	of	ADP
dti-1334	14	18	all	all	DET
dti-1334	14	19	peptides	peptide	NOUN
dti-1334	14	20	by	by	ADP
dti-1334	14	21	employing	employ	VERB
dti-1334	14	22	an	an	DET
dti-1334	14	23	8	8	NUM
dti-1334	14	24	-	-	PUNCT
dti-1334	14	25	plex	plex	NOUN
dti-1334	14	26	set	set	NOUN
dti-1334	14	27	of	of	ADP
dti-1334	14	28	amine	amine	ADJ
dti-1334	14	29	reactive	reactive	ADJ
dti-1334	14	30	tags	tag	NOUN
dti-1334	14	31	to	to	PART
dti-1334	14	32	derivatize	derivatize	VERB
dti-1334	14	33	peptides	peptide	NOUN
dti-1334	14	34	at	at	ADP
dti-1334	14	35	the	the	DET
dti-1334	14	36	n	n	CCONJ
dti-1334	14	37	-	-	PUNCT
dti-1334	14	38	terminus	terminus	NOUN
dti-1334	14	39	and	and	CCONJ
dti-1334	14	40	lysine	lysine	NOUN
dti-1334	14	41	side	side	NOUN
dti-1334	14	42	chains	chain	NOUN
dti-1334	14	43	allowing	allow	VERB
dti-1334	14	44	for	for	ADP
dti-1334	14	45	absolute	absolute	ADJ
dti-1334	14	46	quantifi	quantifi	ADJ
dti-1334	14	47	cation	cation	NOUN
dti-1334	14	48	and	and	CCONJ
dti-1334	14	49	assessment	assessment	NOUN
dti-1334	14	50	of	of	ADP
dti-1334	14	51	ptm	ptm	PROPN
dti-1334	14	52	.	.	PUNCT
dti-1334	15	1	these	these	PRON
dti-1334	15	2	and	and	CCONJ
dti-1334	15	3	other	other	ADJ
dti-1334	15	4	new	new	ADJ
dti-1334	15	5	laboratory	laboratory	NOUN
dti-1334	15	6	technologies	technology	NOUN
dti-1334	15	7	,	,	PUNCT
dti-1334	15	8	along	along	ADP
dti-1334	15	9	with	with	ADP
dti-1334	15	10	improved	improved	ADJ
dti-1334	15	11	bioinformatics	bioinformatics	NOUN
dti-1334	15	12	tools	tool	NOUN
dti-1334	15	13	,	,	PUNCT
dti-1334	15	14	have	have	AUX
dti-1334	15	15	started	start	VERB
dti-1334	15	16	to	to	PART
dti-1334	15	17	make	make	VERB
dti-1334	15	18	signifi	signifi	NOUN
dti-1334	16	1	ca	can	AUX
dti-1334	16	2	nt	not	PART
dti-1334	16	3	contributions	contribution	NOUN
dti-1334	16	4	in	in	ADP
dti-1334	16	5	cancer	cancer	NOUN
dti-1334	16	6	diagnostics	diagnostic	NOUN
dti-1334	16	7	and	and	CCONJ
dti-1334	16	8	treatments	treatment	NOUN
dti-1334	16	9	.	.	PUNCT
dti-1334	17	1	keywords	keyword	NOUN
dti-1334	17	2	:	:	PUNCT
dti-1334	17	3	proteomics	proteomic	NOUN
dti-1334	17	4	,	,	PUNCT
dti-1334	17	5	molecular	molecular	ADJ
dti-1334	17	6	profi	profi	PROPN
dti-1334	17	7	ling	ling	PROPN
dti-1334	17	8	,	,	PUNCT
dti-1334	17	9	targeted	target	VERB
dti-1334	17	10	cancer	cancer	NOUN
dti-1334	17	11	therapy	therapy	NOUN
dti-1334	17	12	introduction	introduction	NOUN
dti-1334	17	13	for	for	ADP
dti-1334	17	14	70	70	NUM
dti-1334	17	15	years	year	NOUN
dti-1334	17	16	the	the	DET
dti-1334	17	17	oncology	oncology	NOUN
dti-1334	17	18	community	community	NOUN
dti-1334	17	19	has	have	AUX
dti-1334	17	20	been	be	AUX
dti-1334	17	21	exploring	explore	VERB
dti-1334	17	22	therapeutic	therapeutic	ADJ
dti-1334	17	23	opportunities	opportunity	NOUN
dti-1334	17	24	involving	involve	VERB
dti-1334	17	25	cytotoxic	cytotoxic	ADJ
dti-1334	17	26	based	base	VERB
dti-1334	17	27	therapy	therapy	NOUN
dti-1334	17	28	for	for	ADP
dti-1334	17	29	cancer	cancer	NOUN
dti-1334	17	30	control	control	NOUN
dti-1334	17	31	.	.	PUNCT
dti-1334	18	1	unfortunately	unfortunately	ADV
dti-1334	18	2	,	,	PUNCT
dti-1334	18	3	principles	principle	NOUN
dti-1334	18	4	derived	derive	VERB
dti-1334	18	5	from	from	ADP
dti-1334	18	6	the	the	DET
dti-1334	18	7	application	application	NOUN
dti-1334	18	8	of	of	ADP
dti-1334	18	9	cytotoxic	cytotoxic	ADJ
dti-1334	18	10	based	base	VERB
dti-1334	18	11	therapies	therapy	NOUN
dti-1334	18	12	now	now	ADV
dti-1334	18	13	provide	provide	VERB
dti-1334	18	14	diminishing	diminishing	NOUN
dti-1334	18	15	return	return	NOUN
dti-1334	18	16	with	with	ADP
dti-1334	18	17	respect	respect	NOUN
dti-1334	18	18	to	to	ADP
dti-1334	18	19	patient	patient	ADJ
dti-1334	18	20	benefi	benefi	NOUN
dti-1334	18	21	t.	t.	PROPN
dti-1334	18	22	recent	recent	ADJ
dti-1334	18	23	developments	development	NOUN
dti-1334	18	24	in	in	ADP
dti-1334	18	25	genetics	genetic	NOUN
dti-1334	18	26	,	,	PUNCT
dti-1334	18	27	molecular	molecular	ADJ
dti-1334	18	28	biology	biology	NOUN
dti-1334	18	29	,	,	PUNCT
dti-1334	18	30	and	and	CCONJ
dti-1334	18	31	molecular	molecular	ADJ
dti-1334	18	32	pharmacology	pharmacology	NOUN
dti-1334	18	33	promise	promise	NOUN
dti-1334	18	34	to	to	PART
dti-1334	18	35	dramatically	dramatically	ADV
dti-1334	18	36	alter	alter	VERB
dti-1334	18	37	strategies	strategy	NOUN
dti-1334	18	38	of	of	ADP
dti-1334	18	39	cancer	cancer	NOUN
dti-1334	18	40	management	management	NOUN
dti-1334	18	41	.	.	PUNCT
dti-1334	19	1	our	our	PRON
dti-1334	19	2	ability	ability	NOUN
dti-1334	19	3	to	to	PART
dti-1334	19	4	differentially	differentially	ADV
dti-1334	19	5	characterize	characterize	VERB
dti-1334	19	6	the	the	DET
dti-1334	19	7	neoplastic	neoplastic	ADJ
dti-1334	19	8	process	process	NOUN
dti-1334	19	9	in	in	ADP
dti-1334	19	10	malignant	malignant	ADJ
dti-1334	19	11	cells	cell	NOUN
dti-1334	19	12	on	on	ADP
dti-1334	19	13	the	the	DET
dti-1334	19	14	bases	basis	NOUN
dti-1334	19	15	of	of	ADP
dti-1334	19	16	receptor	receptor	NOUN
dti-1334	19	17	overexpression	overexpression	NOUN
dti-1334	19	18	,	,	PUNCT
dti-1334	19	19	signaling	signal	VERB
dti-1334	19	20	process	process	NOUN
dti-1334	19	21	modulation	modulation	NOUN
dti-1334	19	22	,	,	PUNCT
dti-1334	19	23	and	and	CCONJ
dti-1334	19	24	genetic	genetic	ADJ
dti-1334	19	25	and	and	CCONJ
dti-1334	19	26	epigenetic	epigenetic	ADJ
dti-1334	19	27	aberrations	aberration	NOUN
dti-1334	19	28	is	be	AUX
dti-1334	19	29	now	now	ADV
dti-1334	19	30	enabling	enable	VERB
dti-1334	19	31	us	we	PRON
dti-1334	19	32	to	to	PART
dti-1334	19	33	realistically	realistically	ADV
dti-1334	19	34	entertain	entertain	VERB
dti-1334	19	35	the	the	DET
dti-1334	19	36	concept	concept	NOUN
dti-1334	19	37	of	of	ADP
dti-1334	19	38	specifi	specifi	PROPN
dti-1334	19	39	cally	cally	ADV
dti-1334	19	40	matching	match	VERB
dti-1334	19	41	the	the	DET
dti-1334	19	42	“	"	PUNCT
dti-1334	19	43	right	right	ADJ
dti-1334	19	44	patient	patient	NOUN
dti-1334	19	45	with	with	ADP
dti-1334	19	46	the	the	DET
dti-1334	19	47	right	right	ADJ
dti-1334	19	48	therapeutic	therapeutic	ADJ
dti-1334	19	49	”	"	PUNCT
dti-1334	19	50	.	.	PUNCT
dti-1334	20	1	molecular	molecular	ADJ
dti-1334	20	2	characterization	characterization	NOUN
dti-1334	20	3	of	of	ADP
dti-1334	20	4	relatively	relatively	ADV
dti-1334	20	5	sensitive	sensitive	ADJ
dti-1334	20	6	and	and	CCONJ
dti-1334	20	7	differentially	differentially	ADV
dti-1334	20	8	specifi	specifi	PROPN
dti-1334	20	9	c	c	PROPN
dti-1334	20	10	cancer	cancer	NOUN
dti-1334	20	11	structural	structural	ADJ
dti-1334	20	12	and	and	CCONJ
dti-1334	20	13	process	process	NOUN
dti-1334	20	14	components	component	NOUN
dti-1334	20	15	has	have	AUX
dti-1334	20	16	resulted	result	VERB
dti-1334	20	17	in	in	ADP
dti-1334	20	18	a	a	DET
dti-1334	20	19	new	new	ADJ
dti-1334	20	20	wave	wave	NOUN
dti-1334	20	21	of	of	ADP
dti-1334	20	22	“	"	PUNCT
dti-1334	20	23	targeted	targeted	ADJ
dti-1334	20	24	”	"	PUNCT
dti-1334	20	25	therapies	therapy	NOUN
dti-1334	20	26	.	.	PUNCT
dti-1334	21	1	in	in	ADP
dti-1334	21	2	a	a	DET
dti-1334	21	3	scale	scale	NOUN
dti-1334	21	4	-	-	PUNCT
dti-1334	21	5	free	free	ADJ
dti-1334	21	6	,	,	PUNCT
dti-1334	21	7	hierarchical	hierarchical	ADJ
dti-1334	21	8	,	,	PUNCT
dti-1334	21	9	modular	modular	ADJ
dti-1334	21	10	system	system	NOUN
dti-1334	21	11	such	such	ADJ
dti-1334	21	12	as	as	ADP
dti-1334	21	13	cancer	cancer	NOUN
dti-1334	21	14	,	,	PUNCT
dti-1334	21	15	redundancy	redundancy	NOUN
dti-1334	21	16	enables	enable	VERB
dti-1334	21	17	most	most	ADJ
dti-1334	21	18	neoplastic	neoplastic	ADJ
dti-1334	21	19	cells	cell	NOUN
dti-1334	21	20	to	to	PART
dti-1334	21	21	bypass	bypass	VERB
dti-1334	21	22	or	or	CCONJ
dti-1334	21	23	buffer	buffer	VERB
dti-1334	21	24	the	the	DET
dti-1334	21	25	effect	effect	NOUN
dti-1334	21	26	of	of	ADP
dti-1334	21	27	any	any	DET
dti-1334	21	28	single	single	ADJ
dti-1334	21	29	gene	gene	NOUN
dti-1334	21	30	/	/	SYM
dti-1334	21	31	target	target	NOUN
dti-1334	21	32	modifi	modifi	NOUN
dti-1334	21	33	cation	cation	NOUN
dti-1334	21	34	,	,	PUNCT
dti-1334	21	35	thereby	thereby	ADV
dti-1334	21	36	minimizing	minimize	VERB
dti-1334	21	37	targeted	target	VERB
dti-1334	21	38	therapeutic	therapeutic	ADJ
dti-1334	21	39	effectiveness	effectiveness	NOUN
dti-1334	21	40	and	and	CCONJ
dti-1334	21	41	the	the	DET
dti-1334	21	42	capacity	capacity	NOUN
dti-1334	21	43	for	for	ADP
dti-1334	21	44	long	long	ADJ
dti-1334	21	45	term	term	NOUN
dti-1334	21	46	durable	durable	ADJ
dti-1334	21	47	response	response	NOUN
dti-1334	21	48	(	(	PUNCT
dti-1334	21	49	carlson	carlson	PROPN
dti-1334	21	50	and	and	CCONJ
dti-1334	21	51	doyle	doyle	PROPN
dti-1334	21	52	,	,	PUNCT
dti-1334	21	53	2002	2002	NUM
dti-1334	21	54	;	;	PUNCT
dti-1334	21	55	ciliberti	ciliberti	PROPN
dti-1334	21	56	et	et	PROPN
dti-1334	21	57	al	al	PROPN
dti-1334	21	58	.	.	PROPN
dti-1334	21	59	2007	2007	NUM
dti-1334	21	60	)	)	PUNCT
dti-1334	21	61	.	.	PUNCT
dti-1334	22	1	however	however	ADV
dti-1334	22	2	,	,	PUNCT
dti-1334	22	3	systems	system	NOUN
dti-1334	22	4	biology	biology	NOUN
dti-1334	22	5	analysis	analysis	NOUN
dti-1334	22	6	suggests	suggest	VERB
dti-1334	22	7	that	that	SCONJ
dti-1334	22	8	coordinated	coordinate	VERB
dti-1334	22	9	and	and	CCONJ
dti-1334	22	10	integrated	integrate	VERB
dti-1334	22	11	targeted	target	VERB
dti-1334	22	12	(	(	PUNCT
dti-1334	22	13	rather	rather	ADV
dti-1334	22	14	than	than	ADP
dti-1334	22	15	‘	'	PUNCT
dti-1334	22	16	random	random	ADJ
dti-1334	22	17	’	'	PUNCT
dti-1334	22	18	)	)	PUNCT
dti-1334	22	19	network	network	NOUN
dti-1334	22	20	disruptions	disruption	NOUN
dti-1334	22	21	can	can	AUX
dti-1334	22	22	expose	expose	VERB
dti-1334	22	23	an	an	DET
dti-1334	22	24	“	"	PUNCT
dti-1334	22	25	attack	attack	NOUN
dti-1334	22	26	vulnerability	vulnerability	NOUN
dti-1334	22	27	”	"	PUNCT
dti-1334	22	28	(	(	PUNCT
dti-1334	22	29	carlson	carlson	NOUN
dti-1334	22	30	and	and	CCONJ
dti-1334	22	31	doyle	doyle	PROPN
dti-1334	22	32	,	,	PUNCT
dti-1334	22	33	2002	2002	NUM
dti-1334	22	34	;	;	PUNCT
dti-1334	22	35	hartwell	hartwell	PROPN
dti-1334	22	36	et	et	PROPN
dti-1334	22	37	al	al	PROPN
dti-1334	22	38	.	.	PROPN
dti-1334	22	39	1997	1997	NUM
dti-1334	22	40	)	)	PUNCT
dti-1334	22	41	.	.	PUNCT
dti-1334	23	1	as	as	ADP
dti-1334	23	2	such	such	ADJ
dti-1334	23	3	,	,	PUNCT
dti-1334	23	4	the	the	DET
dti-1334	23	5	disordered	disordered	ADJ
dti-1334	23	6	system	system	NOUN
dti-1334	23	7	circuitry	circuitry	NOUN
dti-1334	23	8	can	can	AUX
dti-1334	23	9	become	become	VERB
dti-1334	23	10	,	,	PUNCT
dti-1334	23	11	almost	almost	ADV
dti-1334	23	12	paradoxically	paradoxically	ADV
dti-1334	23	13	,	,	PUNCT
dti-1334	23	14	more	more	ADV
dti-1334	23	15	highly	highly	ADV
dti-1334	23	16	dependent	dependent	ADJ
dti-1334	23	17	on	on	ADP
dti-1334	23	18	a	a	DET
dti-1334	23	19	specifi	specifi	PROPN
dti-1334	23	20	c	c	PROPN
dti-1334	23	21	rewired	rewire	VERB
dti-1334	23	22	pathway	pathway	NOUN
dti-1334	23	23	(	(	PUNCT
dti-1334	23	24	i.e.	i.e.	X
dti-1334	23	25	pathway	pathway	NOUN
dti-1334	23	26	addiction	addiction	NOUN
dti-1334	23	27	)	)	PUNCT
dti-1334	23	28	.	.	PUNCT
dti-1334	24	1	in	in	ADP
dti-1334	24	2	other	other	ADJ
dti-1334	24	3	words	word	NOUN
dti-1334	24	4	,	,	PUNCT
dti-1334	24	5	the	the	DET
dti-1334	24	6	disruption	disruption	NOUN
dti-1334	24	7	of	of	ADP
dti-1334	24	8	pathways	pathway	NOUN
dti-1334	24	9	that	that	PRON
dti-1334	24	10	produce	produce	VERB
dti-1334	24	11	robustness	robustness	NOUN
dti-1334	24	12	to	to	ADP
dti-1334	24	13	certain	certain	ADJ
dti-1334	24	14	insults	insult	NOUN
dti-1334	24	15	are	be	AUX
dti-1334	24	16	often	often	ADV
dti-1334	24	17	associated	associate	VERB
dti-1334	24	18	with	with	ADP
dti-1334	24	19	enhanced	enhanced	ADJ
dti-1334	24	20	fragility	fragility	NOUN
dti-1334	24	21	to	to	ADP
dti-1334	24	22	other	other	ADJ
dti-1334	24	23	perturbations	perturbation	NOUN
dti-1334	24	24	thereby	thereby	ADV
dti-1334	24	25	exposing	expose	VERB
dti-1334	24	26	an	an	DET
dti-1334	24	27	“	"	PUNCT
dti-1334	24	28	achilles	achille	NOUN
dti-1334	24	29	’	'	PUNCT
dti-1334	24	30	heel	heel	NOUN
dti-1334	24	31	”	"	PUNCT
dti-1334	24	32	of	of	ADP
dti-1334	24	33	cancer	cancer	NOUN
dti-1334	24	34	.	.	PUNCT
dti-1334	25	1	in	in	ADP
dti-1334	25	2	such	such	DET
dti-1334	25	3	an	an	DET
dti-1334	25	4	approach	approach	NOUN
dti-1334	25	5	,	,	PUNCT
dti-1334	25	6	the	the	DET
dti-1334	25	7	most	most	ADV
dti-1334	25	8	intriguing	intriguing	ADJ
dti-1334	25	9	targets	target	NOUN
dti-1334	25	10	derived	derive	VERB
dti-1334	25	11	from	from	ADP
dti-1334	25	12	a	a	DET
dti-1334	25	13	patient	patient	NOUN
dti-1334	25	14	’s	’s	PART
dti-1334	25	15	differential	differential	ADJ
dti-1334	25	16	genomic	genomic	ADJ
dti-1334	25	17	-	-	PUNCT
dti-1334	25	18	proteomic	proteomic	NOUN
dti-1334	25	19	profi	profi	PROPN
dti-1334	25	20	le	le	PROPN
dti-1334	25	21	,	,	PUNCT
dti-1334	25	22	which	which	PRON
dti-1334	25	23	we	we	PRON
dti-1334	25	24	are	be	AUX
dti-1334	25	25	studying	study	VERB
dti-1334	25	26	,	,	PUNCT
dti-1334	25	27	would	would	AUX
dti-1334	25	28	involve	involve	VERB
dti-1334	25	29	highly	highly	ADV
dti-1334	25	30	interconnected	interconnected	ADJ
dti-1334	25	31	“	"	PUNCT
dti-1334	25	32	hub	hub	NOUN
dti-1334	25	33	”	"	PUNCT
dti-1334	25	34	genes	gene	NOUN
dti-1334	25	35	which	which	PRON
dti-1334	25	36	control	control	VERB
dti-1334	25	37	cancer	cancer	NOUN
dti-1334	25	38	cell	cell	NOUN
dti-1334	25	39	competitive	competitive	ADJ
dti-1334	25	40	survival	survival	NOUN
dti-1334	25	41	,	,	PUNCT
dti-1334	25	42	metastagenicity	metastagenicity	NOUN
dti-1334	25	43	and/or	and/or	CCONJ
dti-1334	25	44	cancer	cancer	NOUN
dti-1334	25	45	stem	stem	NOUN
dti-1334	25	46	-	-	PUNCT
dti-1334	25	47	cell	cell	NOUN
dti-1334	25	48	renewal	renewal	NOUN
dti-1334	25	49	(	(	PUNCT
dti-1334	25	50	albert	albert	PROPN
dti-1334	25	51	et	et	PROPN
dti-1334	25	52	al	al	PROPN
dti-1334	25	53	.	.	PROPN
dti-1334	25	54	2000	2000	NUM
dti-1334	25	55	;	;	PUNCT
dti-1334	25	56	jeong	jeong	PROPN
dti-1334	25	57	et	et	PROPN
dti-1334	25	58	al	al	PROPN
dti-1334	25	59	.	.	PROPN
dti-1334	25	60	2001	2001	NUM
dti-1334	25	61	)	)	PUNCT
dti-1334	25	62	.	.	PUNCT
dti-1334	26	1	we	we	PRON
dti-1334	26	2	and	and	CCONJ
dti-1334	26	3	others	other	NOUN
dti-1334	26	4	have	have	AUX
dti-1334	26	5	previously	previously	ADV
dti-1334	26	6	demonstrated	demonstrate	VERB
dti-1334	26	7	that	that	SCONJ
dti-1334	26	8	semi	semi	ADJ
dti-1334	26	9	-	-	ADJ
dti-1334	26	10	quantitative	quantitative	ADJ
dti-1334	26	11	proteomic	proteomic	NOUN
dti-1334	26	12	(	(	PUNCT
dti-1334	26	13	feldman	feldman	PROPN
dti-1334	26	14	et	et	PROPN
dti-1334	26	15	al	al	PROPN
dti-1334	26	16	.	.	PROPN
dti-1334	26	17	2004	2004	NUM
dti-1334	26	18	;	;	PUNCT
dti-1334	26	19	nemunaitis	nemunaitis	PROPN
dti-1334	26	20	et	et	PROPN
dti-1334	26	21	al	al	PROPN
dti-1334	26	22	.	.	PROPN
dti-1334	26	23	2007	2007	NUM
dti-1334	26	24	;	;	PUNCT
dti-1334	26	25	petricoin	petricoin	PROPN
dti-1334	26	26	et	et	PROPN
dti-1334	26	27	al	al	PROPN
dti-1334	26	28	.	.	PROPN
dti-1334	26	29	2004	2004	NUM
dti-1334	26	30	;	;	PUNCT
dti-1334	26	31	zhou	zhou	PROPN
dti-1334	26	32	et	et	PROPN
dti-1334	26	33	al	al	PROPN
dti-1334	26	34	.	.	PROPN
dti-1334	26	35	2002	2002	NUM
dti-1334	26	36	)	)	PUNCT
dti-1334	26	37	profi	profi	PROPN
dti-1334	26	38	ling	ling	PROPN
dti-1334	26	39	derived	derive	VERB
dti-1334	26	40	by	by	ADP
dti-1334	26	41	comparing	compare	VERB
dti-1334	26	42	malignant	malignant	ADJ
dti-1334	26	43	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN
dti-1334	26	44	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN
dti-1334	26	45	56	56	NUM
dti-1334	26	46	shen	shen	NOUN
dti-1334	26	47	et	et	PROPN
dti-1334	26	48	al	al	PROPN
dti-1334	26	49	drug	drug	PROPN
dti-1334	26	50	target	target	NOUN
dti-1334	26	51	insights	insight	NOUN
dti-1334	26	52	2008:3	2008:3	NUM
dti-1334	26	53	and	and	CCONJ
dti-1334	26	54	non	non	ADJ
dti-1334	26	55	-	-	ADJ
dti-1334	26	56	malignant	malignant	ADJ
dti-1334	26	57	tissue	tissue	NOUN
dti-1334	26	58	from	from	ADP
dti-1334	26	59	patients	patient	NOUN
dti-1334	26	60	with	with	ADP
dti-1334	26	61	progressive	progressive	ADJ
dti-1334	26	62	cancer	cancer	NOUN
dti-1334	26	63	can	can	AUX
dti-1334	26	64	be	be	AUX
dti-1334	26	65	analyzed	analyze	VERB
dti-1334	26	66	in	in	ADP
dti-1334	26	67	the	the	DET
dti-1334	26	68	context	context	NOUN
dti-1334	26	69	of	of	ADP
dti-1334	26	70	global	global	ADJ
dti-1334	26	71	protein	protein	NOUN
dti-1334	26	72	interaction	interaction	NOUN
dti-1334	26	73	networks	network	NOUN
dti-1334	26	74	in	in	ADP
dti-1334	26	75	order	order	NOUN
dti-1334	26	76	to	to	PART
dti-1334	26	77	generate	generate	VERB
dti-1334	26	78	a	a	DET
dti-1334	26	79	prioritized	prioritize	VERB
dti-1334	26	80	list	list	NOUN
dti-1334	26	81	of	of	ADP
dti-1334	26	82	potential	potential	ADJ
dti-1334	26	83	protein	protein	NOUN
dti-1334	26	84	and	and	CCONJ
dti-1334	26	85	gene	gene	NOUN
dti-1334	26	86	targets	target	NOUN
dti-1334	26	87	.	.	PUNCT
dti-1334	27	1	compared	compare	VERB
dti-1334	27	2	to	to	ADP
dti-1334	27	3	cdna	cdna	PROPN
dti-1334	27	4	microarray	microarray	PROPN
dti-1334	27	5	studies	study	NOUN
dti-1334	27	6	,	,	PUNCT
dti-1334	27	7	analysis	analysis	NOUN
dti-1334	27	8	of	of	ADP
dti-1334	27	9	differential	differential	ADJ
dti-1334	27	10	gene	gene	NOUN
dti-1334	27	11	expression	expression	NOUN
dti-1334	27	12	at	at	ADP
dti-1334	27	13	the	the	DET
dti-1334	27	14	protein	protein	NOUN
dti-1334	27	15	level	level	NOUN
dti-1334	27	16	presents	present	VERB
dti-1334	27	17	unique	unique	ADJ
dti-1334	27	18	advantages	advantage	NOUN
dti-1334	27	19	as	as	SCONJ
dti-1334	27	20	proteins	protein	NOUN
dti-1334	27	21	are	be	AUX
dti-1334	27	22	the	the	DET
dti-1334	27	23	mediate	mediate	NOUN
dti-1334	27	24	,	,	PUNCT
dti-1334	27	25	if	if	SCONJ
dti-1334	27	26	not	not	PART
dti-1334	27	27	direct	direct	ADJ
dti-1334	27	28	,	,	PUNCT
dti-1334	27	29	effectors	effector	NOUN
dti-1334	27	30	of	of	ADP
dti-1334	27	31	cellular	cellular	ADJ
dti-1334	27	32	behavior	behavior	NOUN
dti-1334	27	33	.	.	PUNCT
dti-1334	28	1	furthermore	furthermore	ADV
dti-1334	28	2	,	,	PUNCT
dti-1334	28	3	the	the	DET
dti-1334	28	4	products	product	NOUN
dti-1334	28	5	of	of	ADP
dti-1334	28	6	posttranslational	posttranslational	ADJ
dti-1334	28	7	modifi	modifi	NOUN
dti-1334	28	8	cations	cation	NOUN
dti-1334	28	9	and	and	CCONJ
dti-1334	28	10	differential	differential	ADJ
dti-1334	28	11	rna	rna	NOUN
dti-1334	28	12	splicing	splicing	NOUN
dti-1334	28	13	,	,	PUNCT
dti-1334	28	14	as	as	ADV
dti-1334	28	15	well	well	ADV
dti-1334	28	16	as	as	ADP
dti-1334	28	17	samples	sample	NOUN
dti-1334	28	18	with	with	ADP
dti-1334	28	19	limited	limited	ADJ
dti-1334	28	20	nucleic	nucleic	ADJ
dti-1334	28	21	acids	acid	NOUN
dti-1334	28	22	(	(	PUNCT
dti-1334	28	23	e.g.	e.g.	ADV
dti-1334	28	24	serum	serum	NOUN
dti-1334	28	25	)	)	PUNCT
dti-1334	28	26	are	be	AUX
dti-1334	28	27	most	most	ADV
dti-1334	28	28	effectively	effectively	ADV
dti-1334	28	29	analyzed	analyze	VERB
dti-1334	28	30	using	use	VERB
dti-1334	28	31	proteomics	proteomic	NOUN
dti-1334	28	32	approaches	approach	NOUN
dti-1334	28	33	.	.	PUNCT
dti-1334	29	1	thus	thus	ADV
dti-1334	29	2	far	far	ADV
dti-1334	29	3	,	,	PUNCT
dti-1334	29	4	proteomics	proteomic	NOUN
dti-1334	29	5	analyses	analysis	NOUN
dti-1334	29	6	have	have	AUX
dti-1334	29	7	been	be	AUX
dti-1334	29	8	used	use	VERB
dti-1334	29	9	to	to	PART
dti-1334	29	10	probe	probe	VERB
dti-1334	29	11	the	the	DET
dti-1334	29	12	cellular	cellular	ADJ
dti-1334	29	13	and	and	CCONJ
dti-1334	29	14	molecular	molecular	ADJ
dti-1334	29	15	mechanisms	mechanism	NOUN
dti-1334	29	16	of	of	ADP
dti-1334	29	17	transformation	transformation	NOUN
dti-1334	29	18	(	(	PUNCT
dti-1334	29	19	young	young	ADJ
dti-1334	29	20	et	et	PROPN
dti-1334	29	21	al	al	PROPN
dti-1334	29	22	.	.	PROPN
dti-1334	29	23	2005	2005	NUM
dti-1334	29	24	)	)	PUNCT
dti-1334	29	25	,	,	PUNCT
dti-1334	29	26	search	search	NOUN
dti-1334	29	27	for	for	ADP
dti-1334	29	28	determination	determination	NOUN
dti-1334	29	29	of	of	ADP
dti-1334	29	30	potential	potential	ADJ
dti-1334	29	31	tumor	tumor	NOUN
dti-1334	29	32	biomarkers	biomarker	NOUN
dti-1334	29	33	(	(	PUNCT
dti-1334	29	34	zhou	zhou	PROPN
dti-1334	29	35	et	et	PROPN
dti-1334	29	36	al	al	PROPN
dti-1334	29	37	.	.	PROPN
dti-1334	29	38	2002	2002	NUM
dti-1334	29	39	)	)	PUNCT
dti-1334	29	40	,	,	PUNCT
dti-1334	29	41	screen	screen	NOUN
dti-1334	29	42	and	and	CCONJ
dti-1334	29	43	allow	allow	VERB
dti-1334	29	44	early	early	ADJ
dti-1334	29	45	detection	detection	NOUN
dti-1334	29	46	of	of	ADP
dti-1334	29	47	cancer	cancer	NOUN
dti-1334	29	48	(	(	PUNCT
dti-1334	29	49	feldman	feldman	PROPN
dti-1334	29	50	et	et	PROPN
dti-1334	29	51	al	al	PROPN
dti-1334	29	52	.	.	PROPN
dti-1334	29	53	2004	2004	NUM
dti-1334	29	54	;	;	PUNCT
dti-1334	29	55	petricoin	petricoin	PROPN
dti-1334	29	56	et	et	PROPN
dti-1334	29	57	al	al	PROPN
dti-1334	29	58	.	.	PROPN
dti-1334	29	59	2004	2004	NUM
dti-1334	29	60	)	)	PUNCT
dti-1334	29	61	,	,	PUNCT
dti-1334	29	62	prognosticate	prognosticate	VERB
dti-1334	29	63	,	,	PUNCT
dti-1334	29	64	predict	predict	VERB
dti-1334	29	65	response	response	NOUN
dti-1334	29	66	and	and	CCONJ
dti-1334	29	67	support	support	VERB
dti-1334	29	68	therapeutic	therapeutic	ADJ
dti-1334	29	69	management	management	NOUN
dti-1334	29	70	of	of	ADP
dti-1334	29	71	cancer	cancer	NOUN
dti-1334	29	72	(	(	PUNCT
dti-1334	29	73	nagata	nagata	PROPN
dti-1334	29	74	et	et	PROPN
dti-1334	29	75	al	al	PROPN
dti-1334	29	76	.	.	PROPN
dti-1334	29	77	2004	2004	NUM
dti-1334	29	78	;	;	PUNCT
dti-1334	29	79	volpi	volpi	PROPN
dti-1334	29	80	et	et	PROPN
dti-1334	29	81	al	al	PROPN
dti-1334	29	82	.	.	PROPN
dti-1334	29	83	2003	2003	NUM
dti-1334	29	84	)	)	PUNCT
dti-1334	29	85	.	.	PUNCT
dti-1334	30	1	it	it	PRON
dti-1334	30	2	is	be	AUX
dti-1334	30	3	hoped	hope	VERB
dti-1334	30	4	that	that	SCONJ
dti-1334	30	5	one	one	NUM
dti-1334	30	6	day	day	NOUN
dti-1334	30	7	the	the	DET
dti-1334	30	8	knowledge	knowledge	NOUN
dti-1334	30	9	of	of	ADP
dti-1334	30	10	proteomic	proteomic	ADJ
dti-1334	30	11	signals	signal	NOUN
dti-1334	30	12	within	within	ADP
dti-1334	30	13	individual	individual	ADJ
dti-1334	30	14	cancer	cancer	NOUN
dti-1334	30	15	specimens	specimen	NOUN
dti-1334	30	16	prior	prior	ADV
dti-1334	30	17	to	to	ADP
dti-1334	30	18	treatment	treatment	NOUN
dti-1334	30	19	will	will	AUX
dti-1334	30	20	provide	provide	VERB
dti-1334	30	21	a	a	DET
dti-1334	30	22	more	more	ADV
dti-1334	30	23	optimal	optimal	ADJ
dti-1334	30	24	match	match	NOUN
dti-1334	30	25	between	between	ADP
dti-1334	30	26	the	the	DET
dti-1334	30	27	patient	patient	NOUN
dti-1334	30	28	and	and	CCONJ
dti-1334	30	29	a	a	DET
dti-1334	30	30	molecular	molecular	ADJ
dti-1334	30	31	based	base	VERB
dti-1334	30	32	targeted	target	VERB
dti-1334	30	33	therapy	therapy	NOUN
dti-1334	30	34	opportunity	opportunity	NOUN
dti-1334	30	35	,	,	PUNCT
dti-1334	30	36	thereby	thereby	ADV
dti-1334	30	37	enhancing	enhance	VERB
dti-1334	30	38	clinical	clinical	ADJ
dti-1334	30	39	response	response	NOUN
dti-1334	30	40	predictability	predictability	NOUN
dti-1334	30	41	for	for	ADP
dti-1334	30	42	the	the	DET
dti-1334	30	43	clinical	clinical	ADJ
dti-1334	30	44	treatment	treatment	NOUN
dti-1334	30	45	team	team	NOUN
dti-1334	30	46	and	and	CCONJ
dti-1334	30	47	the	the	DET
dti-1334	30	48	patient	patient	NOUN
dti-1334	30	49	.	.	PUNCT
dti-1334	31	1	proteomics	proteomic	NOUN
dti-1334	31	2	technologies	technology	NOUN
dti-1334	31	3	while	while	SCONJ
dti-1334	31	4	many	many	ADJ
dti-1334	31	5	proteomics	proteomic	NOUN
dti-1334	31	6	strategies	strategy	NOUN
dti-1334	31	7	have	have	AUX
dti-1334	31	8	been	be	AUX
dti-1334	31	9	designed	design	VERB
dti-1334	31	10	and	and	CCONJ
dti-1334	31	11	tested	test	VERB
dti-1334	31	12	,	,	PUNCT
dti-1334	31	13	only	only	ADV
dti-1334	31	14	a	a	DET
dti-1334	31	15	handful	handful	NOUN
dti-1334	31	16	have	have	AUX
dti-1334	31	17	been	be	AUX
dti-1334	31	18	widely	widely	ADV
dti-1334	31	19	used	use	VERB
dti-1334	31	20	.	.	PUNCT
dti-1334	32	1	these	these	DET
dti-1334	32	2	technologies	technology	NOUN
dti-1334	32	3	along	along	ADP
dti-1334	32	4	with	with	ADP
dti-1334	32	5	their	their	PRON
dti-1334	32	6	advantages	advantage	NOUN
dti-1334	32	7	and	and	CCONJ
dti-1334	32	8	disadvantages	disadvantage	NOUN
dti-1334	32	9	are	be	AUX
dti-1334	32	10	discussed	discuss	VERB
dti-1334	32	11	below	below	ADV
dti-1334	32	12	.	.	PUNCT
dti-1334	33	1	polyacrylamide	polyacrylamide	NOUN
dti-1334	33	2	gel	gel	PROPN
dti-1334	33	3	electrophoresis	electrophoresis	NOUN
dti-1334	33	4	(	(	PUNCT
dti-1334	33	5	page	page	NOUN
dti-1334	33	6	)	)	PUNCT
dti-1334	33	7	polyacrylamide	polyacrylamide	NOUN
dti-1334	33	8	gel	gel	NOUN
dti-1334	33	9	electrophoresis	electrophoresis	NOUN
dti-1334	33	10	(	(	PUNCT
dti-1334	33	11	page	page	NOUN
dti-1334	33	12	)	)	PUNCT
dti-1334	33	13	is	be	AUX
dti-1334	33	14	one	one	NUM
dti-1334	33	15	of	of	ADP
dti-1334	33	16	the	the	DET
dti-1334	33	17	most	most	ADV
dti-1334	33	18	widely	widely	ADV
dti-1334	33	19	used	use	VERB
dti-1334	33	20	techniques	technique	NOUN
dti-1334	33	21	for	for	ADP
dti-1334	33	22	separation	separation	NOUN
dti-1334	33	23	of	of	ADP
dti-1334	33	24	complex	complex	ADJ
dti-1334	33	25	protein	protein	NOUN
dti-1334	33	26	mixtures	mixture	NOUN
dti-1334	33	27	(	(	PUNCT
dti-1334	33	28	somiari	somiari	PROPN
dti-1334	33	29	et	et	PROPN
dti-1334	33	30	al	al	PROPN
dti-1334	33	31	.	.	PROPN
dti-1334	33	32	2005	2005	NUM
dti-1334	33	33	)	)	PUNCT
dti-1334	33	34	.	.	PUNCT
dti-1334	34	1	upon	upon	SCONJ
dti-1334	34	2	completion	completion	NOUN
dti-1334	34	3	of	of	ADP
dti-1334	34	4	page	page	NOUN
dti-1334	34	5	,	,	PUNCT
dti-1334	34	6	the	the	DET
dti-1334	34	7	proteins	protein	NOUN
dti-1334	34	8	of	of	ADP
dti-1334	34	9	interest	interest	NOUN
dti-1334	34	10	are	be	AUX
dti-1334	34	11	excised	excise	VERB
dti-1334	34	12	from	from	ADP
dti-1334	34	13	the	the	DET
dti-1334	34	14	gel	gel	NOUN
dti-1334	34	15	and	and	CCONJ
dti-1334	34	16	their	their	PRON
dti-1334	34	17	identities	identity	NOUN
dti-1334	34	18	are	be	AUX
dti-1334	34	19	determined	determine	VERB
dti-1334	34	20	by	by	ADP
dti-1334	34	21	mass	mass	ADJ
dti-1334	34	22	spectrometry	spectrometry	NOUN
dti-1334	34	23	.	.	PUNCT
dti-1334	35	1	there	there	PRON
dti-1334	35	2	are	be	VERB
dti-1334	35	3	mainly	mainly	ADV
dti-1334	35	4	two	two	NUM
dti-1334	35	5	versions	version	NOUN
dti-1334	35	6	of	of	ADP
dti-1334	35	7	page	page	NOUN
dti-1334	35	8	:	:	PUNCT
dti-1334	35	9	one	one	NUM
dti-1334	35	10	-	-	PUNCT
dti-1334	35	11	dimensional	dimensional	ADJ
dti-1334	35	12	gel	gel	NOUN
dti-1334	35	13	electrophoresis	electrophoresis	NOUN
dti-1334	35	14	(	(	PUNCT
dti-1334	35	15	1	1	NUM
dti-1334	35	16	-	-	PUNCT
dti-1334	35	17	d	d	NOUN
dti-1334	35	18	page	page	NOUN
dti-1334	35	19	or	or	CCONJ
dti-1334	35	20	sds	sds	NOUN
dti-1334	35	21	-	-	PUNCT
dti-1334	35	22	page	page	NOUN
dti-1334	35	23	)	)	PUNCT
dti-1334	35	24	and	and	CCONJ
dti-1334	35	25	twodimensional	twodimensional	ADJ
dti-1334	35	26	gel	gel	NOUN
dti-1334	35	27	electrophoresis	electrophoresis	NOUN
dti-1334	35	28	(	(	PUNCT
dti-1334	35	29	2	2	NUM
dti-1334	35	30	-	-	PUNCT
dti-1334	35	31	d	d	NOUN
dti-1334	35	32	page	page	NOUN
dti-1334	35	33	)	)	PUNCT
dti-1334	35	34	.	.	PUNCT
dti-1334	36	1	in	in	ADP
dti-1334	36	2	1	1	NUM
dti-1334	36	3	-	-	PUNCT
dti-1334	36	4	d	d	NOUN
dti-1334	36	5	page	page	NOUN
dti-1334	36	6	,	,	PUNCT
dti-1334	36	7	the	the	DET
dti-1334	36	8	protein	protein	NOUN
dti-1334	36	9	samples	sample	NOUN
dti-1334	36	10	are	be	AUX
dti-1334	36	11	dissolved	dissolve	VERB
dti-1334	36	12	in	in	ADP
dti-1334	36	13	a	a	DET
dti-1334	36	14	loading	loading	NOUN
dti-1334	36	15	buffer	buffer	NOUN
dti-1334	36	16	that	that	PRON
dti-1334	36	17	usually	usually	ADV
dti-1334	36	18	contains	contain	VERB
dti-1334	36	19	a	a	DET
dti-1334	36	20	reducing	reduce	VERB
dti-1334	36	21	agent	agent	NOUN
dti-1334	36	22	(	(	PUNCT
dti-1334	36	23	for	for	ADP
dti-1334	36	24	example	example	NOUN
dti-1334	36	25	,	,	PUNCT
dti-1334	36	26	dithiothreitol	dithiothreitol	PROPN
dti-1334	36	27	)	)	PUNCT
dti-1334	36	28	and	and	CCONJ
dti-1334	36	29	a	a	DET
dti-1334	36	30	denaturing	denature	VERB
dti-1334	36	31	agent	agent	NOUN
dti-1334	36	32	[	[	X
dti-1334	36	33	for	for	ADP
dti-1334	36	34	example	example	NOUN
dti-1334	36	35	,	,	PUNCT
dti-1334	36	36	sodium	sodium	NOUN
dti-1334	36	37	dodecyl	dodecyl	PROPN
dti-1334	36	38	sulphate	sulphate	NOUN
dti-1334	36	39	(	(	PUNCT
dti-1334	36	40	sds	sds	PROPN
dti-1334	36	41	)	)	PUNCT
dti-1334	36	42	]	]	PUNCT
dti-1334	36	43	.	.	PUNCT
dti-1334	37	1	separation	separation	NOUN
dti-1334	37	2	is	be	AUX
dti-1334	37	3	primarily	primarily	ADV
dti-1334	37	4	based	base	VERB
dti-1334	37	5	on	on	ADP
dti-1334	37	6	the	the	DET
dti-1334	37	7	molecular	molecular	ADJ
dti-1334	37	8	weight	weight	NOUN
dti-1334	37	9	of	of	ADP
dti-1334	37	10	the	the	DET
dti-1334	37	11	proteins	protein	NOUN
dti-1334	37	12	in	in	ADP
dti-1334	37	13	the	the	DET
dti-1334	37	14	samples	sample	NOUN
dti-1334	37	15	.	.	PUNCT
dti-1334	38	1	after	after	ADP
dti-1334	38	2	electrophoresis	electrophoresis	NOUN
dti-1334	38	3	,	,	PUNCT
dti-1334	38	4	proteins	protein	NOUN
dti-1334	38	5	are	be	AUX
dti-1334	38	6	visualized	visualize	VERB
dti-1334	38	7	either	either	CCONJ
dti-1334	38	8	by	by	ADP
dti-1334	38	9	using	use	VERB
dti-1334	38	10	antibody	antibody	NOUN
dti-1334	38	11	-	-	PUNCT
dti-1334	38	12	detection	detection	NOUN
dti-1334	38	13	techniques	technique	NOUN
dti-1334	38	14	or	or	CCONJ
dti-1334	38	15	by	by	ADP
dti-1334	38	16	staining	stain	VERB
dti-1334	38	17	the	the	DET
dti-1334	38	18	gel	gel	NOUN
dti-1334	38	19	with	with	ADP
dti-1334	38	20	coomassie	coomassie	ADJ
dti-1334	38	21	brilliant	brilliant	ADJ
dti-1334	38	22	blue	blue	ADJ
dti-1334	38	23	dye	dye	NOUN
dti-1334	38	24	,	,	PUNCT
dti-1334	38	25	silver	silver	NOUN
dti-1334	38	26	stain	stain	NOUN
dti-1334	38	27	or	or	CCONJ
dti-1334	38	28	a	a	DET
dti-1334	38	29	fl	fl	NUM
dti-1334	38	30	uorescent	uorescent	ADJ
dti-1334	38	31	dye	dye	NOUN
dti-1334	38	32	.	.	PUNCT
dti-1334	39	1	the	the	DET
dti-1334	39	2	degree	degree	NOUN
dti-1334	39	3	of	of	ADP
dti-1334	39	4	protein	protein	NOUN
dti-1334	39	5	separation	separation	NOUN
dti-1334	39	6	(	(	PUNCT
dti-1334	39	7	resolution	resolution	NOUN
dti-1334	39	8	)	)	PUNCT
dti-1334	39	9	is	be	AUX
dti-1334	39	10	rather	rather	ADV
dti-1334	39	11	low	low	ADJ
dti-1334	39	12	.	.	PUNCT
dti-1334	40	1	a	a	DET
dti-1334	40	2	single	single	ADJ
dti-1334	40	3	protein	protein	NOUN
dti-1334	40	4	band	band	NOUN
dti-1334	40	5	may	may	AUX
dti-1334	40	6	contain	contain	VERB
dti-1334	40	7	several	several	ADJ
dti-1334	40	8	hundred	hundred	NUM
dti-1334	40	9	proteins	protein	NOUN
dti-1334	40	10	.	.	PUNCT
dti-1334	41	1	thus	thus	ADV
dti-1334	41	2	,	,	PUNCT
dti-1334	41	3	1	1	NUM
dti-1334	41	4	-	-	SYM
dti-1334	41	5	d	d	NOUN
dti-1334	41	6	page	page	NOUN
dti-1334	41	7	is	be	AUX
dti-1334	41	8	of	of	ADP
dti-1334	41	9	little	little	ADJ
dti-1334	41	10	utility	utility	NOUN
dti-1334	41	11	in	in	ADP
dti-1334	41	12	proteomic	proteomic	ADJ
dti-1334	41	13	analysis	analysis	NOUN
dti-1334	41	14	of	of	ADP
dti-1334	41	15	complex	complex	ADJ
dti-1334	41	16	protein	protein	NOUN
dti-1334	41	17	samples	sample	NOUN
dti-1334	41	18	.	.	PUNCT
dti-1334	42	1	for	for	ADP
dti-1334	42	2	many	many	ADJ
dti-1334	42	3	years	year	NOUN
dti-1334	42	4	,	,	PUNCT
dti-1334	42	5	2	2	NUM
dti-1334	42	6	-	-	SYM
dti-1334	42	7	d	d	NOUN
dti-1334	42	8	page	page	NOUN
dti-1334	42	9	has	have	AUX
dti-1334	42	10	been	be	AUX
dti-1334	42	11	the	the	DET
dti-1334	42	12	“	"	PUNCT
dti-1334	42	13	benchmark	benchmark	NOUN
dti-1334	42	14	”	"	PUNCT
dti-1334	42	15	for	for	ADP
dti-1334	42	16	large	large	ADJ
dti-1334	42	17	-	-	PUNCT
dti-1334	42	18	scale	scale	NOUN
dti-1334	42	19	separation	separation	NOUN
dti-1334	42	20	of	of	ADP
dti-1334	42	21	complex	complex	ADJ
dti-1334	42	22	protein	protein	NOUN
dti-1334	42	23	mixtures	mixture	NOUN
dti-1334	42	24	.	.	PUNCT
dti-1334	43	1	it	it	PRON
dti-1334	43	2	separates	separate	VERB
dti-1334	43	3	proteins	protein	NOUN
dti-1334	43	4	by	by	ADP
dti-1334	43	5	the	the	DET
dti-1334	43	6	sequential	sequential	ADJ
dti-1334	43	7	orthogonal	orthogonal	ADJ
dti-1334	43	8	use	use	NOUN
dti-1334	43	9	of	of	ADP
dti-1334	43	10	two	two	NUM
dti-1334	43	11	different	different	ADJ
dti-1334	43	12	electrophoretic	electrophoretic	ADJ
dti-1334	43	13	techniques	technique	NOUN
dti-1334	43	14	based	base	VERB
dti-1334	43	15	on	on	ADP
dti-1334	43	16	two	two	NUM
dti-1334	43	17	different	different	ADJ
dti-1334	43	18	properties	property	NOUN
dti-1334	43	19	of	of	ADP
dti-1334	43	20	the	the	DET
dti-1334	43	21	proteins	protein	NOUN
dti-1334	43	22	.	.	PUNCT
dti-1334	44	1	proteins	protein	NOUN
dti-1334	44	2	are	be	AUX
dti-1334	44	3	fi	fi	NOUN
dti-1334	44	4	rst	rst	PROPN
dti-1334	44	5	separated	separate	VERB
dti-1334	44	6	by	by	ADP
dti-1334	44	7	iso	iso	NOUN
dti-1334	44	8	-	-	PUNCT
dti-1334	44	9	electric	electric	ADJ
dti-1334	44	10	focusing	focus	VERB
dti-1334	44	11	(	(	PUNCT
dti-1334	44	12	ief	ief	NOUN
dti-1334	44	13	)	)	PUNCT
dti-1334	44	14	based	base	VERB
dti-1334	44	15	on	on	ADP
dti-1334	44	16	their	their	PRON
dti-1334	44	17	isoelectric	isoelectric	ADJ
dti-1334	44	18	point	point	NOUN
dti-1334	44	19	.	.	PUNCT
dti-1334	45	1	subsequently	subsequently	ADV
dti-1334	45	2	,	,	PUNCT
dti-1334	45	3	the	the	DET
dti-1334	45	4	proteins	protein	NOUN
dti-1334	45	5	are	be	AUX
dti-1334	45	6	separated	separate	VERB
dti-1334	45	7	in	in	ADP
dti-1334	45	8	the	the	DET
dti-1334	45	9	presence	presence	NOUN
dti-1334	45	10	of	of	ADP
dti-1334	45	11	sds	sds	PROPN
dti-1334	45	12	according	accord	VERB
dti-1334	45	13	to	to	ADP
dti-1334	45	14	their	their	PRON
dti-1334	45	15	molecular	molecular	ADJ
dti-1334	45	16	weights	weight	NOUN
dti-1334	45	17	.	.	PUNCT
dti-1334	46	1	protein	protein	NOUN
dti-1334	46	2	detection	detection	NOUN
dti-1334	46	3	after	after	SCONJ
dti-1334	46	4	2d	2d	NOUN
dti-1334	46	5	-	-	PUNCT
dti-1334	46	6	page	page	NOUN
dti-1334	46	7	utilizes	utilize	VERB
dti-1334	46	8	either	either	CCONJ
dti-1334	46	9	antibody	antibody	NOUN
dti-1334	46	10	-	-	PUNCT
dti-1334	46	11	detection	detection	NOUN
dti-1334	46	12	techniques	technique	NOUN
dti-1334	46	13	or	or	CCONJ
dti-1334	46	14	gel	gel	NOUN
dti-1334	46	15	staining	stain	VERB
dti-1334	46	16	techniques	technique	NOUN
dti-1334	46	17	as	as	SCONJ
dti-1334	46	18	described	describe	VERB
dti-1334	46	19	for	for	ADP
dti-1334	46	20	1	1	NUM
dti-1334	46	21	-	-	PUNCT
dti-1334	46	22	d	d	NOUN
dti-1334	46	23	page	page	NOUN
dti-1334	46	24	.	.	PUNCT
dti-1334	47	1	the	the	DET
dti-1334	47	2	proteins	protein	NOUN
dti-1334	47	3	on	on	ADP
dti-1334	47	4	the	the	DET
dti-1334	47	5	gel	gel	NOUN
dti-1334	47	6	are	be	AUX
dti-1334	47	7	detected	detect	VERB
dti-1334	47	8	as	as	ADP
dti-1334	47	9	distinct	distinct	ADJ
dti-1334	47	10	spots	spot	NOUN
dti-1334	47	11	which	which	PRON
dti-1334	47	12	can	can	AUX
dti-1334	47	13	be	be	AUX
dti-1334	47	14	identifi	identifi	PROPN
dti-1334	47	15	ed	ed	NOUN
dti-1334	47	16	by	by	ADP
dti-1334	47	17	mass	mass	ADJ
dti-1334	47	18	spectrometry	spectrometry	NOUN
dti-1334	47	19	.	.	PUNCT
dti-1334	48	1	a	a	DET
dti-1334	48	2	few	few	ADJ
dti-1334	48	3	hundred	hundred	NUM
dti-1334	48	4	to	to	ADP
dti-1334	48	5	a	a	DET
dti-1334	48	6	few	few	ADJ
dti-1334	48	7	thousand	thousand	NUM
dti-1334	48	8	spots	spot	NOUN
dti-1334	48	9	can	can	AUX
dti-1334	48	10	be	be	AUX
dti-1334	48	11	detected	detect	VERB
dti-1334	48	12	on	on	ADP
dti-1334	48	13	a	a	DET
dti-1334	48	14	2	2	NUM
dti-1334	48	15	-	-	PUNCT
dti-1334	48	16	d	d	NOUN
dti-1334	48	17	gel	gel	NOUN
dti-1334	48	18	based	base	VERB
dti-1334	48	19	on	on	ADP
dti-1334	48	20	the	the	DET
dti-1334	48	21	specifi	specifi	PROPN
dti-1334	48	22	cs	cs	PROPN
dti-1334	48	23	of	of	ADP
dti-1334	48	24	the	the	DET
dti-1334	48	25	gel	gel	NOUN
dti-1334	48	26	size	size	NOUN
dti-1334	48	27	and	and	CCONJ
dti-1334	48	28	electrophoresis	electrophoresis	NOUN
dti-1334	48	29	conditions	condition	NOUN
dti-1334	48	30	.	.	PUNCT
dti-1334	49	1	2d	2d	NOUN
dti-1334	49	2	-	-	PUNCT
dti-1334	49	3	page	page	NOUN
dti-1334	49	4	was	be	AUX
dti-1334	49	5	fi	fi	NOUN
dti-1334	49	6	rst	rst	PROPN
dti-1334	49	7	developed	develop	VERB
dti-1334	49	8	by	by	ADP
dti-1334	49	9	o’farrell	o’farrell	PROPN
dti-1334	49	10	(	(	PUNCT
dti-1334	49	11	1975	1975	NUM
dti-1334	49	12	)	)	PUNCT
dti-1334	49	13	but	but	CCONJ
dti-1334	49	14	has	have	AUX
dti-1334	49	15	subsequently	subsequently	ADV
dti-1334	49	16	undergone	undergo	VERB
dti-1334	49	17	several	several	ADJ
dti-1334	49	18	modifications	modification	NOUN
dti-1334	49	19	designed	design	VERB
dti-1334	49	20	to	to	PART
dti-1334	49	21	improve	improve	VERB
dti-1334	49	22	its	its	PRON
dti-1334	49	23	resolution	resolution	NOUN
dti-1334	49	24	,	,	PUNCT
dti-1334	49	25	reliability	reliability	NOUN
dti-1334	49	26	and	and	CCONJ
dti-1334	49	27	sensitivity	sensitivity	NOUN
dti-1334	49	28	[	[	X
dti-1334	49	29	for	for	ADP
dti-1334	49	30	example	example	NOUN
dti-1334	49	31	,	,	PUNCT
dti-1334	49	32	see	see	VERB
dti-1334	49	33	yan	yan	PROPN
dti-1334	49	34	et	et	PROPN
dti-1334	49	35	al	al	PROPN
dti-1334	49	36	.	.	PUNCT
dti-1334	50	1	(	(	PUNCT
dti-1334	50	2	yan	yan	PROPN
dti-1334	50	3	et	et	PROPN
dti-1334	50	4	al	al	PROPN
dti-1334	50	5	.	.	PROPN
dti-1334	50	6	1999	1999	NUM
dti-1334	50	7	)	)	PUNCT
dti-1334	50	8	]	]	PUNCT
dti-1334	50	9	.	.	PUNCT
dti-1334	51	1	integrated	integrate	VERB
dti-1334	51	2	imaging	imaging	NOUN
dti-1334	51	3	and	and	CCONJ
dti-1334	51	4	bioinformatics	bioinformatics	NOUN
dti-1334	51	5	tools	tool	NOUN
dti-1334	51	6	are	be	AUX
dti-1334	51	7	now	now	ADV
dti-1334	51	8	available	available	ADJ
dti-1334	51	9	for	for	ADP
dti-1334	51	10	proteomic	proteomic	ADJ
dti-1334	51	11	characterization	characterization	NOUN
dti-1334	51	12	of	of	ADP
dti-1334	51	13	biological	biological	ADJ
dti-1334	51	14	specimens	specimen	NOUN
dti-1334	51	15	.	.	PUNCT
dti-1334	52	1	the	the	DET
dti-1334	52	2	recently	recently	ADV
dti-1334	52	3	introduced	introduce	VERB
dti-1334	52	4	modifi	modifi	NOUN
dti-1334	52	5	cation	cation	NOUN
dti-1334	52	6	of	of	ADP
dti-1334	52	7	2	2	NUM
dti-1334	52	8	-	-	PUNCT
dti-1334	52	9	d	d	NOUN
dti-1334	52	10	page	page	NOUN
dti-1334	52	11	,	,	PUNCT
dti-1334	52	12	termed	term	VERB
dti-1334	52	13	two	two	NUM
dti-1334	52	14	-	-	PUNCT
dti-1334	52	15	dimensional	dimensional	ADJ
dti-1334	52	16	differential	differential	NOUN
dti-1334	52	17	in	in	ADP
dti-1334	52	18	-	-	PUNCT
dti-1334	52	19	gel	gel	NOUN
dti-1334	52	20	electrophoresis	electrophoresis	NOUN
dti-1334	52	21	(	(	PUNCT
dti-1334	52	22	2	2	NUM
dti-1334	52	23	-	-	PUNCT
dti-1334	52	24	d	d	NOUN
dti-1334	52	25	dige	dige	NOUN
dti-1334	52	26	)	)	PUNCT
dti-1334	52	27	,	,	PUNCT
dti-1334	52	28	has	have	AUX
dti-1334	52	29	significantly	significantly	ADV
dti-1334	52	30	improved	improve	VERB
dti-1334	52	31	the	the	DET
dti-1334	52	32	speed	speed	NOUN
dti-1334	52	33	,	,	PUNCT
dti-1334	52	34	reproducibility	reproducibility	NOUN
dti-1334	52	35	and	and	CCONJ
dti-1334	52	36	sensitivity	sensitivity	NOUN
dti-1334	52	37	of	of	ADP
dti-1334	52	38	2	2	NUM
dti-1334	52	39	-	-	PUNCT
dti-1334	52	40	d	d	NOUN
dti-1334	52	41	page	page	NOUN
dti-1334	52	42	based	base	VERB
dti-1334	52	43	proteomics	proteomic	NOUN
dti-1334	52	44	(	(	PUNCT
dti-1334	52	45	friedman	friedman	PROPN
dti-1334	52	46	,	,	PUNCT
dti-1334	52	47	2007	2007	NUM
dti-1334	52	48	;	;	PUNCT
dti-1334	52	49	friedman	friedman	PROPN
dti-1334	52	50	et	et	PROPN
dti-1334	52	51	al	al	PROPN
dti-1334	52	52	.	.	PROPN
dti-1334	52	53	2004	2004	NUM
dti-1334	52	54	;	;	PUNCT
dti-1334	52	55	somiari	somiari	PROPN
dti-1334	52	56	et	et	PROPN
dti-1334	52	57	al	al	PROPN
dti-1334	52	58	.	.	PROPN
dti-1334	52	59	2003	2003	NUM
dti-1334	52	60	;	;	PUNCT
dti-1334	52	61	wu	wu	PROPN
dti-1334	52	62	et	et	PROPN
dti-1334	52	63	al	al	PROPN
dti-1334	52	64	.	.	PROPN
dti-1334	52	65	2006	2006	NUM
dti-1334	52	66	;	;	PUNCT
dti-1334	52	67	wu	wu	PROPN
dti-1334	52	68	,	,	PUNCT
dti-1334	52	69	2006	2006	NUM
dti-1334	52	70	)	)	PUNCT
dti-1334	52	71	.	.	PUNCT
dti-1334	53	1	using	use	VERB
dti-1334	53	2	different	different	ADJ
dti-1334	53	3	fl	fl	PRON
dti-1334	53	4	uorescent	uorescent	ADJ
dti-1334	53	5	dyes	dye	NOUN
dti-1334	53	6	to	to	PART
dti-1334	53	7	label	label	NOUN
dti-1334	53	8	protein	protein	NOUN
dti-1334	53	9	samples	sample	NOUN
dti-1334	53	10	prior	prior	ADV
dti-1334	53	11	to	to	ADP
dti-1334	53	12	gel	gel	NOUN
dti-1334	53	13	electrophoresis	electrophoresis	NOUN
dti-1334	53	14	,	,	PUNCT
dti-1334	53	15	the	the	DET
dti-1334	53	16	dige	dige	NOUN
dti-1334	53	17	technique	technique	NOUN
dti-1334	53	18	allows	allow	VERB
dti-1334	53	19	multiple	multiple	ADJ
dti-1334	53	20	samples	sample	NOUN
dti-1334	53	21	to	to	PART
dti-1334	53	22	be	be	AUX
dti-1334	53	23	co	co	VERB
dti-1334	53	24	-	-	VERB
dti-1334	53	25	separated	separate	VERB
dti-1334	53	26	and	and	CCONJ
dti-1334	53	27	visualized	visualize	VERB
dti-1334	53	28	on	on	ADP
dti-1334	53	29	one	one	NUM
dti-1334	53	30	2	2	NUM
dti-1334	53	31	-	-	PUNCT
dti-1334	53	32	d	d	NOUN
dti-1334	53	33	gel	gel	NOUN
dti-1334	53	34	(	(	PUNCT
dti-1334	53	35	unlu	unlu	NOUN
dti-1334	53	36	et	et	PROPN
dti-1334	53	37	al	al	PROPN
dti-1334	53	38	.	.	PROPN
dti-1334	53	39	1997	1997	NUM
dti-1334	53	40	)	)	PUNCT
dti-1334	53	41	.	.	PUNCT
dti-1334	54	1	up	up	ADP
dti-1334	54	2	to	to	PART
dti-1334	54	3	three	three	NUM
dti-1334	54	4	protein	protein	NOUN
dti-1334	54	5	extracts	extract	NOUN
dti-1334	54	6	,	,	PUNCT
dti-1334	54	7	for	for	ADP
dti-1334	54	8	example	example	NOUN
dti-1334	54	9	one	one	NUM
dti-1334	54	10	control	control	NOUN
dti-1334	54	11	and	and	CCONJ
dti-1334	54	12	two	two	NUM
dti-1334	54	13	treated	treat	VERB
dti-1334	54	14	,	,	PUNCT
dti-1334	54	15	are	be	AUX
dti-1334	54	16	labeled	label	VERB
dti-1334	54	17	covalently	covalently	ADV
dti-1334	54	18	with	with	ADP
dti-1334	54	19	different	different	ADJ
dti-1334	54	20	fl	fl	PRON
dti-1334	54	21	uorescent	uorescent	ADJ
dti-1334	54	22	dyes	dye	NOUN
dti-1334	54	23	(	(	PUNCT
dti-1334	54	24	cy2	cy2	PROPN
dti-1334	54	25	,	,	PUNCT
dti-1334	54	26	cy3	cy3	NOUN
dti-1334	54	27	and/or	and/or	CCONJ
dti-1334	54	28	cy5	cy5	NOUN
dti-1334	54	29	)	)	PUNCT
dti-1334	54	30	,	,	PUNCT
dti-1334	54	31	then	then	ADV
dti-1334	54	32	combined	combine	VERB
dti-1334	54	33	and	and	CCONJ
dti-1334	54	34	separated	separate	VERB
dti-1334	54	35	by	by	ADP
dti-1334	54	36	2	2	NUM
dti-1334	54	37	-	-	PUNCT
dti-1334	54	38	d	d	NOUN
dti-1334	54	39	page	page	NOUN
dti-1334	54	40	.	.	PUNCT
dti-1334	55	1	up	up	ADP
dti-1334	55	2	to	to	PART
dti-1334	55	3	three	three	NUM
dti-1334	55	4	coincident	coincident	ADJ
dti-1334	55	5	images	image	NOUN
dti-1334	55	6	of	of	ADP
dti-1334	55	7	the	the	DET
dti-1334	55	8	gel	gel	NOUN
dti-1334	55	9	are	be	AUX
dti-1334	55	10	captured	capture	VERB
dti-1334	55	11	—	—	PUNCT
dti-1334	55	12	using	use	VERB
dti-1334	55	13	the	the	DET
dti-1334	55	14	cy2	cy2	ADJ
dti-1334	55	15	,	,	PUNCT
dti-1334	55	16	57	57	NUM
dti-1334	55	17	proteomics	proteomic	NOUN
dti-1334	55	18	in	in	ADP
dti-1334	55	19	personalized	personalized	ADJ
dti-1334	55	20	cancer	cancer	NOUN
dti-1334	55	21	therapy	therapy	NOUN
dti-1334	55	22	drug	drug	NOUN
dti-1334	55	23	target	target	NOUN
dti-1334	55	24	insights	insight	NOUN
dti-1334	55	25	2008:3	2008:3	NUM
dti-1334	55	26	cy3	cy3	NOUN
dti-1334	55	27	and/or	and/or	CCONJ
dti-1334	55	28	cy5	cy5	NOUN
dti-1334	55	29	excitation	excitation	NOUN
dti-1334	55	30	wavelengths	wavelength	NOUN
dti-1334	55	31	.	.	PUNCT
dti-1334	56	1	the	the	DET
dti-1334	56	2	images	image	NOUN
dti-1334	56	3	are	be	AUX
dti-1334	56	4	then	then	ADV
dti-1334	56	5	merged	merge	VERB
dti-1334	56	6	,	,	PUNCT
dti-1334	56	7	and	and	CCONJ
dti-1334	56	8	differences	difference	NOUN
dti-1334	56	9	between	between	ADP
dti-1334	56	10	them	they	PRON
dti-1334	56	11	can	can	AUX
dti-1334	56	12	be	be	AUX
dti-1334	56	13	determined	determine	VERB
dti-1334	56	14	using	use	VERB
dti-1334	56	15	image	image	NOUN
dti-1334	56	16	analysis	analysis	NOUN
dti-1334	56	17	software	software	NOUN
dti-1334	56	18	.	.	PUNCT
dti-1334	57	1	2	2	NUM
dti-1334	57	2	-	-	SYM
dti-1334	57	3	d	d	NOUN
dti-1334	57	4	dige	dige	NOUN
dti-1334	57	5	effectively	effectively	ADV
dti-1334	57	6	eliminates	eliminate	VERB
dti-1334	57	7	gel	gel	NOUN
dti-1334	57	8	-	-	PUNCT
dti-1334	57	9	togel	togel	NOUN
dti-1334	57	10	variability	variability	NOUN
dti-1334	57	11	that	that	PRON
dti-1334	57	12	is	be	AUX
dti-1334	57	13	associated	associate	VERB
dti-1334	57	14	with	with	ADP
dti-1334	57	15	standard	standard	ADJ
dti-1334	57	16	2	2	NUM
dti-1334	57	17	-	-	PUNCT
dti-1334	57	18	d	d	NOUN
dti-1334	57	19	page	page	NOUN
dti-1334	57	20	and	and	CCONJ
dti-1334	57	21	improves	improve	VERB
dti-1334	57	22	the	the	DET
dti-1334	57	23	accuracy	accuracy	NOUN
dti-1334	57	24	of	of	ADP
dti-1334	57	25	quantitative	quantitative	ADJ
dti-1334	57	26	protein	protein	NOUN
dti-1334	57	27	profi	profi	PROPN
dti-1334	57	28	ling	ling	PROPN
dti-1334	57	29	(	(	PUNCT
dti-1334	57	30	friedman	friedman	PROPN
dti-1334	57	31	,	,	PUNCT
dti-1334	57	32	2007	2007	NUM
dti-1334	57	33	)	)	PUNCT
dti-1334	57	34	.	.	PUNCT
dti-1334	58	1	this	this	DET
dti-1334	58	2	technology	technology	NOUN
dti-1334	58	3	has	have	AUX
dti-1334	58	4	been	be	AUX
dti-1334	58	5	used	use	VERB
dti-1334	58	6	for	for	ADP
dti-1334	58	7	protein	protein	NOUN
dti-1334	58	8	profi	profi	NOUN
dti-1334	58	9	ling	ling	PROPN
dti-1334	58	10	in	in	ADP
dti-1334	58	11	numerous	numerous	ADJ
dti-1334	58	12	organisms	organism	NOUN
dti-1334	58	13	including	include	VERB
dti-1334	58	14	bacteria	bacteria	NOUN
dti-1334	58	15	(	(	PUNCT
dti-1334	58	16	rathsam	rathsam	NOUN
dti-1334	58	17	et	et	PROPN
dti-1334	58	18	al	al	PROPN
dti-1334	58	19	.	.	PROPN
dti-1334	58	20	2005	2005	NUM
dti-1334	58	21	)	)	PUNCT
dti-1334	58	22	,	,	PUNCT
dti-1334	58	23	yeast	yeast	NOUN
dti-1334	58	24	(	(	PUNCT
dti-1334	58	25	hu	hu	PROPN
dti-1334	58	26	et	et	PROPN
dti-1334	58	27	al	al	PROPN
dti-1334	58	28	.	.	PROPN
dti-1334	58	29	2003	2003	NUM
dti-1334	58	30	)	)	PUNCT
dti-1334	58	31	,	,	PUNCT
dti-1334	58	32	plants	plant	NOUN
dti-1334	58	33	(	(	PUNCT
dti-1334	58	34	bohler	bohler	NOUN
dti-1334	58	35	et	et	PROPN
dti-1334	58	36	al	al	PROPN
dti-1334	58	37	.	.	PROPN
dti-1334	58	38	2007	2007	NUM
dti-1334	58	39	;	;	PUNCT
dti-1334	58	40	keeler	keeler	PROPN
dti-1334	58	41	et	et	PROPN
dti-1334	58	42	al	al	PROPN
dti-1334	58	43	.	.	PROPN
dti-1334	58	44	2007	2007	NUM
dti-1334	58	45	)	)	PUNCT
dti-1334	58	46	,	,	PUNCT
dti-1334	58	47	animals	animal	NOUN
dti-1334	58	48	(	(	PUNCT
dti-1334	58	49	henkel	henkel	PROPN
dti-1334	58	50	et	et	PROPN
dti-1334	58	51	al	al	PROPN
dti-1334	58	52	.	.	PROPN
dti-1334	58	53	2006	2006	NUM
dti-1334	58	54	;	;	PUNCT
dti-1334	58	55	kisby	kisby	VERB
dti-1334	58	56	et	et	PROPN
dti-1334	58	57	al	al	PROPN
dti-1334	58	58	.	.	PROPN
dti-1334	58	59	2006	2006	NUM
dti-1334	58	60	)	)	PUNCT
dti-1334	58	61	,	,	PUNCT
dti-1334	58	62	and	and	CCONJ
dti-1334	58	63	human	human	NOUN
dti-1334	58	64	(	(	PUNCT
dti-1334	58	65	jin	jin	PROPN
dti-1334	58	66	et	et	PROPN
dti-1334	58	67	al	al	PROPN
dti-1334	58	68	.	.	PROPN
dti-1334	58	69	2007	2007	NUM
dti-1334	58	70	;	;	PUNCT
dti-1334	58	71	reynolds	reynolds	PROPN
dti-1334	58	72	et	et	PROPN
dti-1334	58	73	al	al	PROPN
dti-1334	58	74	.	.	PROPN
dti-1334	58	75	2007	2007	NUM
dti-1334	58	76	)	)	PUNCT
dti-1334	58	77	.	.	PUNCT
dti-1334	59	1	it	it	PRON
dti-1334	59	2	is	be	AUX
dti-1334	59	3	also	also	ADV
dti-1334	59	4	used	use	VERB
dti-1334	59	5	for	for	ADP
dti-1334	59	6	analysis	analysis	NOUN
dti-1334	59	7	of	of	ADP
dti-1334	59	8	phosphoproteins	phosphoprotein	NOUN
dti-1334	59	9	(	(	PUNCT
dti-1334	59	10	stasyk	stasyk	VERB
dti-1334	59	11	et	et	PROPN
dti-1334	59	12	al	al	PROPN
dti-1334	59	13	.	.	PROPN
dti-1334	59	14	2005	2005	NUM
dti-1334	59	15	)	)	PUNCT
dti-1334	59	16	and	and	CCONJ
dti-1334	59	17	protein	protein	NOUN
dti-1334	59	18	-	-	PUNCT
dti-1334	59	19	protein	protein	NOUN
dti-1334	59	20	interaction	interaction	NOUN
dti-1334	59	21	(	(	PUNCT
dti-1334	59	22	lyakhovich	lyakhovich	ADV
dti-1334	59	23	et	et	PROPN
dti-1334	59	24	al	al	PROPN
dti-1334	59	25	.	.	PROPN
dti-1334	59	26	2007	2007	NUM
dti-1334	59	27	)	)	PUNCT
dti-1334	59	28	.	.	PUNCT
dti-1334	60	1	the	the	DET
dti-1334	60	2	dyes	dye	NOUN
dti-1334	60	3	are	be	AUX
dti-1334	60	4	purported	purport	VERB
dti-1334	60	5	to	to	PART
dti-1334	60	6	have	have	VERB
dti-1334	60	7	a	a	DET
dti-1334	60	8	linear	linear	ADJ
dti-1334	60	9	response	response	NOUN
dti-1334	60	10	to	to	ADP
dti-1334	60	11	variation	variation	NOUN
dti-1334	60	12	in	in	ADP
dti-1334	60	13	protein	protein	NOUN
dti-1334	60	14	concentration	concentration	NOUN
dti-1334	60	15	over	over	ADP
dti-1334	60	16	five	five	NUM
dti-1334	60	17	orders	order	NOUN
dti-1334	60	18	of	of	ADP
dti-1334	60	19	magnitude	magnitude	NOUN
dti-1334	60	20	,	,	PUNCT
dti-1334	60	21	offer	offer	VERB
dti-1334	60	22	sub	sub	ADJ
dti-1334	60	23	-	-	ADJ
dti-1334	60	24	nanogram	nanogram	ADJ
dti-1334	60	25	sensitivity	sensitivity	NOUN
dti-1334	60	26	,	,	PUNCT
dti-1334	60	27	and	and	CCONJ
dti-1334	60	28	are	be	AUX
dti-1334	60	29	compatible	compatible	ADJ
dti-1334	60	30	with	with	ADP
dti-1334	60	31	ms	ms	ADJ
dti-1334	60	32	analysis	analysis	NOUN
dti-1334	60	33	.	.	PUNCT
dti-1334	61	1	main	main	ADJ
dti-1334	61	2	disadvantages	disadvantage	NOUN
dti-1334	61	3	to	to	ADP
dti-1334	61	4	this	this	DET
dti-1334	61	5	technology	technology	NOUN
dti-1334	61	6	include	include	VERB
dti-1334	61	7	:	:	PUNCT
dti-1334	61	8	1	1	X
dti-1334	61	9	)	)	PUNCT
dti-1334	61	10	the	the	DET
dti-1334	61	11	high	high	ADJ
dti-1334	61	12	cost	cost	NOUN
dti-1334	61	13	involved	involve	VERB
dti-1334	61	14	in	in	ADP
dti-1334	61	15	acquiring	acquire	VERB
dti-1334	61	16	equipment	equipment	NOUN
dti-1334	61	17	as	as	ADV
dti-1334	61	18	well	well	ADV
dti-1334	61	19	as	as	ADP
dti-1334	61	20	expendable	expendable	ADJ
dti-1334	61	21	supplies	supply	NOUN
dti-1334	61	22	,	,	PUNCT
dti-1334	61	23	such	such	ADJ
dti-1334	61	24	as	as	ADP
dti-1334	61	25	the	the	DET
dti-1334	61	26	fl	fl	PROPN
dti-1334	61	27	uorescent	uorescent	ADJ
dti-1334	61	28	dyes	dye	NOUN
dti-1334	61	29	;	;	PUNCT
dti-1334	61	30	2	2	X
dti-1334	61	31	)	)	PUNCT
dti-1334	61	32	the	the	DET
dti-1334	61	33	labor	labor	NOUN
dti-1334	61	34	-	-	PUNCT
dti-1334	61	35	intensive	intensive	ADJ
dti-1334	61	36	nature	nature	NOUN
dti-1334	61	37	of	of	ADP
dti-1334	61	38	the	the	DET
dti-1334	61	39	method	method	NOUN
dti-1334	61	40	,	,	PUNCT
dti-1334	61	41	which	which	PRON
dti-1334	61	42	limits	limit	VERB
dti-1334	61	43	its	its	PRON
dti-1334	61	44	usefulness	usefulness	NOUN
dti-1334	61	45	as	as	ADP
dti-1334	61	46	a	a	DET
dti-1334	61	47	highthroughput	highthroughput	ADJ
dti-1334	61	48	analytical	analytical	ADJ
dti-1334	61	49	method	method	NOUN
dti-1334	61	50	;	;	PUNCT
dti-1334	61	51	3	3	X
dti-1334	61	52	)	)	PUNCT
dti-1334	61	53	proteins	protein	NOUN
dti-1334	61	54	that	that	PRON
dti-1334	61	55	are	be	AUX
dti-1334	61	56	very	very	ADV
dti-1334	61	57	acidic	acidic	ADJ
dti-1334	61	58	(	(	PUNCT
dti-1334	61	59	ph	ph	X
dti-1334	61	60	�	�	PROPN
dti-1334	61	61	4	4	NUM
dti-1334	61	62	)	)	PUNCT
dti-1334	61	63	or	or	CCONJ
dti-1334	61	64	very	very	ADV
dti-1334	61	65	basic	basic	ADJ
dti-1334	61	66	(	(	PUNCT
dti-1334	61	67	ph	ph	X
dti-1334	61	68	�	�	PROPN
dti-1334	61	69	9	9	NUM
dti-1334	61	70	)	)	PUNCT
dti-1334	61	71	,	,	PUNCT
dti-1334	61	72	have	have	AUX
dti-1334	61	73	high	high	ADJ
dti-1334	61	74	(	(	PUNCT
dti-1334	61	75	�	�	PROPN
dti-1334	61	76	150	150	NUM
dti-1334	61	77	kda	kda	NOUN
dti-1334	61	78	)	)	PUNCT
dti-1334	61	79	or	or	CCONJ
dti-1334	61	80	low	low	ADJ
dti-1334	61	81	molecular	molecular	ADJ
dti-1334	61	82	weight	weight	NOUN
dti-1334	61	83	(	(	PUNCT
dti-1334	61	84	�	�	NOUN
dti-1334	61	85	15	15	NUM
dti-1334	61	86	kda	kda	NOUN
dti-1334	61	87	)	)	PUNCT
dti-1334	61	88	and	and	CCONJ
dti-1334	61	89	proteins	protein	NOUN
dti-1334	61	90	that	that	PRON
dti-1334	61	91	are	be	AUX
dti-1334	61	92	very	very	ADV
dti-1334	61	93	hydrophobic	hydrophobic	ADJ
dti-1334	61	94	are	be	AUX
dti-1334	61	95	diffi	diffi	ADJ
dti-1334	61	96	cult	cult	NOUN
dti-1334	61	97	to	to	PART
dti-1334	61	98	analyze	analyze	VERB
dti-1334	61	99	using	use	VERB
dti-1334	61	100	2	2	NUM
dti-1334	61	101	-	-	PUNCT
dti-1334	61	102	d	d	NOUN
dti-1334	61	103	dige	dige	NOUN
dti-1334	61	104	;	;	PUNCT
dti-1334	61	105	and	and	CCONJ
dti-1334	61	106	4	4	X
dti-1334	61	107	)	)	PUNCT
dti-1334	61	108	its	its	PRON
dti-1334	61	109	detection	detection	NOUN
dti-1334	61	110	sensitivity	sensitivity	NOUN
dti-1334	61	111	dictates	dictate	VERB
dti-1334	61	112	that	that	SCONJ
dti-1334	61	113	many	many	ADJ
dti-1334	61	114	low	low	ADJ
dti-1334	61	115	abundance	abundance	NOUN
dti-1334	61	116	proteins	protein	NOUN
dti-1334	61	117	(	(	PUNCT
dti-1334	61	118	such	such	ADJ
dti-1334	61	119	as	as	ADP
dti-1334	61	120	transcription	transcription	NOUN
dti-1334	61	121	factors	factor	NOUN
dti-1334	61	122	,	,	PUNCT
dti-1334	61	123	many	many	ADJ
dti-1334	61	124	serum	serum	NOUN
dti-1334	61	125	biomarkers	biomarker	NOUN
dti-1334	61	126	)	)	PUNCT
dti-1334	61	127	are	be	AUX
dti-1334	61	128	hard	hard	ADJ
dti-1334	61	129	to	to	PART
dti-1334	61	130	detect	detect	VERB
dti-1334	61	131	with	with	ADP
dti-1334	61	132	this	this	DET
dti-1334	61	133	method	method	NOUN
dti-1334	61	134	.	.	PUNCT
dti-1334	62	1	moreover	moreover	ADV
dti-1334	62	2	,	,	PUNCT
dti-1334	62	3	both	both	DET
dti-1334	62	4	microheterogeneity	microheterogeneity	NOUN
dti-1334	62	5	due	due	ADP
dti-1334	62	6	to	to	PART
dti-1334	62	7	post	post	VERB
dti-1334	62	8	translational	translational	ADJ
dti-1334	62	9	modifi	modifi	NOUN
dti-1334	62	10	cations	cation	NOUN
dti-1334	62	11	(	(	PUNCT
dti-1334	62	12	i.e.	i.e.	X
dti-1334	62	13	one	one	NUM
dti-1334	62	14	protein	protein	NOUN
dti-1334	62	15	producing	produce	VERB
dti-1334	62	16	multiple	multiple	ADJ
dti-1334	62	17	spots	spot	NOUN
dti-1334	62	18	)	)	PUNCT
dti-1334	62	19	and	and	CCONJ
dti-1334	62	20	comigration	comigration	NOUN
dti-1334	62	21	(	(	PUNCT
dti-1334	62	22	one	one	NUM
dti-1334	62	23	spot	spot	NOUN
dti-1334	62	24	containing	contain	VERB
dti-1334	62	25	two	two	NUM
dti-1334	62	26	or	or	CCONJ
dti-1334	62	27	more	more	ADJ
dti-1334	62	28	proteins	protein	NOUN
dti-1334	62	29	)	)	PUNCT
dti-1334	62	30	have	have	AUX
dti-1334	62	31	been	be	AUX
dti-1334	62	32	observed	observe	VERB
dti-1334	62	33	.	.	PUNCT
dti-1334	63	1	two	two	NUM
dti-1334	63	2	approaches	approach	NOUN
dti-1334	63	3	of	of	ADP
dti-1334	63	4	dige	dige	NOUN
dti-1334	63	5	,	,	PUNCT
dti-1334	63	6	termed	term	VERB
dti-1334	63	7	“	"	PUNCT
dti-1334	63	8	minimal	minimal	ADJ
dti-1334	63	9	”	"	PUNCT
dti-1334	63	10	and	and	CCONJ
dti-1334	63	11	“	"	PUNCT
dti-1334	63	12	saturation	saturation	NOUN
dti-1334	63	13	”	"	PUNCT
dti-1334	63	14	labeling	labeling	NOUN
dti-1334	63	15	procedures	procedure	NOUN
dti-1334	63	16	,	,	PUNCT
dti-1334	63	17	have	have	AUX
dti-1334	63	18	been	be	AUX
dti-1334	63	19	described	describe	VERB
dti-1334	63	20	.	.	PUNCT
dti-1334	64	1	the	the	DET
dti-1334	64	2	minimal	minimal	ADJ
dti-1334	64	3	labeling	labeling	NOUN
dti-1334	64	4	procedure	procedure	NOUN
dti-1334	64	5	(	(	PUNCT
dti-1334	64	6	lilley	lilley	PROPN
dti-1334	64	7	and	and	CCONJ
dti-1334	64	8	friedman	friedman	PROPN
dti-1334	64	9	,	,	PUNCT
dti-1334	64	10	2004	2004	NUM
dti-1334	64	11	;	;	PUNCT
dti-1334	64	12	tannu	tannu	NOUN
dti-1334	64	13	and	and	CCONJ
dti-1334	64	14	hemby	hemby	NOUN
dti-1334	64	15	,	,	PUNCT
dti-1334	64	16	2006b	2006b	NUM
dti-1334	64	17	)	)	PUNCT
dti-1334	64	18	is	be	AUX
dti-1334	64	19	more	more	ADV
dti-1334	64	20	widely	widely	ADV
dti-1334	64	21	used	use	VERB
dti-1334	64	22	.	.	PUNCT
dti-1334	65	1	in	in	ADP
dti-1334	65	2	this	this	DET
dti-1334	65	3	procedure	procedure	NOUN
dti-1334	65	4	,	,	PUNCT
dti-1334	65	5	the	the	DET
dti-1334	65	6	cydyes	cydye	NOUN
dti-1334	65	7	are	be	AUX
dti-1334	65	8	covalently	covalently	ADV
dti-1334	65	9	attached	attach	VERB
dti-1334	65	10	to	to	ADP
dti-1334	65	11	the	the	DET
dti-1334	65	12	lysine	lysine	NOUN
dti-1334	65	13	residue	residue	NOUN
dti-1334	65	14	side	side	NOUN
dti-1334	65	15	chain	chain	NOUN
dti-1334	65	16	.	.	PUNCT
dti-1334	66	1	the	the	DET
dti-1334	66	2	protein	protein	NOUN
dti-1334	66	3	-	-	PUNCT
dti-1334	66	4	to	to	ADP
dti-1334	66	5	-	-	PUNCT
dti-1334	66	6	dye	dye	NOUN
dti-1334	66	7	ratio	ratio	NOUN
dti-1334	66	8	is	be	AUX
dti-1334	66	9	deliberately	deliberately	ADV
dti-1334	66	10	kept	keep	VERB
dti-1334	66	11	high	high	ADJ
dti-1334	66	12	:	:	PUNCT
dti-1334	66	13	only	only	ADV
dti-1334	66	14	2%–5	2%–5	NUM
dti-1334	66	15	%	%	NOUN
dti-1334	66	16	of	of	ADP
dti-1334	66	17	the	the	DET
dti-1334	66	18	protein	protein	NOUN
dti-1334	66	19	molecules	molecule	NOUN
dti-1334	66	20	are	be	AUX
dti-1334	66	21	labeled	label	VERB
dti-1334	66	22	(	(	PUNCT
dti-1334	66	23	thus	thus	ADV
dti-1334	66	24	“	"	PUNCT
dti-1334	66	25	minimal	minimal	ADJ
dti-1334	66	26	labeling	labeling	NOUN
dti-1334	66	27	”	"	PUNCT
dti-1334	66	28	)	)	PUNCT
dti-1334	66	29	,	,	PUNCT
dti-1334	66	30	so	so	SCONJ
dti-1334	66	31	that	that	SCONJ
dti-1334	66	32	only	only	ADV
dti-1334	66	33	the	the	DET
dti-1334	66	34	proteins	protein	NOUN
dti-1334	66	35	containing	contain	VERB
dti-1334	66	36	a	a	DET
dti-1334	66	37	single	single	ADJ
dti-1334	66	38	dye	dye	NOUN
dti-1334	66	39	molecule	molecule	NOUN
dti-1334	66	40	are	be	AUX
dti-1334	66	41	visualized	visualize	VERB
dti-1334	66	42	on	on	ADP
dti-1334	66	43	the	the	DET
dti-1334	66	44	gel	gel	NOUN
dti-1334	66	45	.	.	PUNCT
dti-1334	67	1	saturation	saturation	NOUN
dti-1334	67	2	labeling	labeling	NOUN
dti-1334	67	3	procedure	procedure	NOUN
dti-1334	67	4	(	(	PUNCT
dti-1334	67	5	kondo	kondo	NOUN
dti-1334	67	6	and	and	CCONJ
dti-1334	67	7	hirohashi	hirohashi	PROPN
dti-1334	67	8	,	,	PUNCT
dti-1334	67	9	2006	2006	NUM
dti-1334	67	10	;	;	PUNCT
dti-1334	67	11	sitek	sitek	PROPN
dti-1334	67	12	et	et	PROPN
dti-1334	67	13	al	al	PROPN
dti-1334	67	14	.	.	PROPN
dti-1334	67	15	2006	2006	NUM
dti-1334	67	16	)	)	PUNCT
dti-1334	67	17	attaches	attach	VERB
dti-1334	67	18	dye	dye	NOUN
dti-1334	67	19	molecules	molecule	NOUN
dti-1334	67	20	to	to	ADP
dti-1334	67	21	cysteine	cysteine	NOUN
dti-1334	67	22	residues	residue	NOUN
dti-1334	67	23	,	,	PUNCT
dti-1334	67	24	and	and	CCONJ
dti-1334	67	25	all	all	DET
dti-1334	67	26	available	available	ADJ
dti-1334	67	27	cysteine	cysteine	NOUN
dti-1334	67	28	residues	residue	NOUN
dti-1334	67	29	are	be	AUX
dti-1334	67	30	labeled	label	VERB
dti-1334	67	31	(	(	PUNCT
dti-1334	67	32	“	"	PUNCT
dti-1334	67	33	saturation	saturation	NOUN
dti-1334	67	34	labeling	labeling	NOUN
dti-1334	67	35	”	"	PUNCT
dti-1334	67	36	)	)	PUNCT
dti-1334	67	37	,	,	PUNCT
dti-1334	67	38	thereby	thereby	ADV
dti-1334	67	39	increasing	increase	VERB
dti-1334	67	40	the	the	DET
dti-1334	67	41	fl	fl	NUM
dti-1334	67	42	uorescent	uorescent	ADJ
dti-1334	67	43	signal	signal	NOUN
dti-1334	67	44	and	and	CCONJ
dti-1334	67	45	protein	protein	NOUN
dti-1334	67	46	detection	detection	NOUN
dti-1334	67	47	sensitivity	sensitivity	NOUN
dti-1334	67	48	.	.	PUNCT
dti-1334	68	1	the	the	DET
dti-1334	68	2	saturation	saturation	NOUN
dti-1334	68	3	labeling	labeling	NOUN
dti-1334	68	4	procedure	procedure	NOUN
dti-1334	68	5	is	be	AUX
dti-1334	68	6	used	use	VERB
dti-1334	68	7	specifi	specifi	PROPN
dti-1334	68	8	cally	cally	ADV
dti-1334	68	9	for	for	ADP
dti-1334	68	10	the	the	DET
dti-1334	68	11	analyses	analysis	NOUN
dti-1334	68	12	of	of	ADP
dti-1334	68	13	scarce	scarce	ADJ
dti-1334	68	14	protein	protein	NOUN
dti-1334	68	15	samples	sample	NOUN
dti-1334	68	16	,	,	PUNCT
dti-1334	68	17	for	for	ADP
dti-1334	68	18	example	example	NOUN
dti-1334	68	19	,	,	PUNCT
dti-1334	68	20	samples	sample	NOUN
dti-1334	68	21	obtained	obtain	VERB
dti-1334	68	22	by	by	ADP
dti-1334	68	23	laser	laser	NOUN
dti-1334	68	24	capture	capture	NOUN
dti-1334	68	25	microdissection	microdissection	NOUN
dti-1334	68	26	(	(	PUNCT
dti-1334	68	27	kondo	kondo	PROPN
dti-1334	68	28	and	and	CCONJ
dti-1334	68	29	hirohashi	hirohashi	PROPN
dti-1334	68	30	,	,	PUNCT
dti-1334	68	31	2006	2006	NUM
dti-1334	68	32	;	;	PUNCT
dti-1334	68	33	sitek	sitek	PROPN
dti-1334	68	34	et	et	PROPN
dti-1334	68	35	al	al	PROPN
dti-1334	68	36	.	.	PROPN
dti-1334	68	37	2006	2006	NUM
dti-1334	68	38	)	)	PUNCT
dti-1334	68	39	.	.	PUNCT
dti-1334	69	1	however	however	ADV
dti-1334	69	2	,	,	PUNCT
dti-1334	69	3	saturation	saturation	NOUN
dti-1334	69	4	labelling	labelling	NOUN
dti-1334	69	5	has	have	VERB
dti-1334	69	6	also	also	ADV
dti-1334	69	7	several	several	ADJ
dti-1334	69	8	drawbacks	drawback	NOUN
dti-1334	69	9	:	:	PUNCT
dti-1334	69	10	(	(	PUNCT
dti-1334	69	11	i	i	NOUN
dti-1334	69	12	)	)	PUNCT
dti-1334	69	13	the	the	DET
dti-1334	69	14	2	2	NUM
dti-1334	69	15	-	-	PUNCT
dti-1334	69	16	d	d	NOUN
dti-1334	69	17	spot	spot	NOUN
dti-1334	69	18	pattern	pattern	NOUN
dti-1334	69	19	is	be	AUX
dti-1334	69	20	signifi	signifi	NOUN
dti-1334	69	21	cantly	cantly	ADV
dti-1334	69	22	altered	alter	VERB
dti-1334	69	23	compared	compare	VERB
dti-1334	69	24	to	to	ADP
dti-1334	69	25	that	that	PRON
dti-1334	69	26	of	of	ADP
dti-1334	69	27	unlabelled	unlabelled	ADJ
dti-1334	69	28	or	or	CCONJ
dti-1334	69	29	minimal	minimal	ADJ
dti-1334	69	30	-	-	PUNCT
dti-1334	69	31	labeled	label	VERB
dti-1334	69	32	proteins	protein	NOUN
dti-1334	69	33	;	;	PUNCT
dti-1334	69	34	(	(	PUNCT
dti-1334	69	35	ii	ii	NOUN
dti-1334	69	36	)	)	PUNCT
dti-1334	69	37	the	the	DET
dti-1334	69	38	labeling	labeling	NOUN
dti-1334	69	39	reaction	reaction	NOUN
dti-1334	69	40	must	must	AUX
dti-1334	69	41	be	be	AUX
dti-1334	69	42	optimized	optimize	VERB
dti-1334	69	43	for	for	SCONJ
dti-1334	69	44	each	each	DET
dti-1334	69	45	sample	sample	NOUN
dti-1334	69	46	to	to	PART
dti-1334	69	47	produce	produce	VERB
dti-1334	69	48	a	a	DET
dti-1334	69	49	uniform	uniform	ADJ
dti-1334	69	50	labeling	labeling	NOUN
dti-1334	69	51	of	of	ADP
dti-1334	69	52	proteins	protein	NOUN
dti-1334	69	53	,	,	PUNCT
dti-1334	69	54	which	which	PRON
dti-1334	69	55	is	be	AUX
dti-1334	69	56	a	a	DET
dti-1334	69	57	timeconsuming	timeconsuming	ADJ
dti-1334	69	58	and	and	CCONJ
dti-1334	69	59	laborious	laborious	ADJ
dti-1334	69	60	procedure	procedure	NOUN
dti-1334	69	61	;	;	PUNCT
dti-1334	69	62	(	(	PUNCT
dti-1334	69	63	iii	iii	X
dti-1334	69	64	)	)	PUNCT
dti-1334	69	65	proteins	protein	NOUN
dti-1334	69	66	may	may	AUX
dti-1334	69	67	precipitate	precipitate	VERB
dti-1334	69	68	during	during	ADP
dti-1334	69	69	the	the	DET
dti-1334	69	70	labeling	labeling	NOUN
dti-1334	69	71	reaction	reaction	NOUN
dti-1334	69	72	due	due	ADP
dti-1334	69	73	to	to	ADP
dti-1334	69	74	the	the	DET
dti-1334	69	75	introduction	introduction	NOUN
dti-1334	69	76	of	of	ADP
dti-1334	69	77	the	the	DET
dti-1334	69	78	hydrophobic	hydrophobic	ADJ
dti-1334	69	79	dye	dye	NOUN
dti-1334	69	80	molecule	molecule	NOUN
dti-1334	69	81	;	;	PUNCT
dti-1334	69	82	and	and	CCONJ
dti-1334	69	83	(	(	PUNCT
dti-1334	69	84	iv	iv	X
dti-1334	69	85	)	)	PUNCT
dti-1334	69	86	currently	currently	ADV
dti-1334	69	87	only	only	ADV
dti-1334	69	88	two	two	NUM
dti-1334	69	89	different	different	ADJ
dti-1334	69	90	saturation	saturation	NOUN
dti-1334	69	91	labeling	labeling	NOUN
dti-1334	69	92	dyes	dye	NOUN
dti-1334	69	93	are	be	AUX
dti-1334	69	94	available	available	ADJ
dti-1334	69	95	,	,	PUNCT
dti-1334	69	96	which	which	PRON
dti-1334	69	97	excludes	exclude	VERB
dti-1334	69	98	the	the	DET
dti-1334	69	99	use	use	NOUN
dti-1334	69	100	of	of	ADP
dti-1334	69	101	an	an	DET
dti-1334	69	102	internal	internal	ADJ
dti-1334	69	103	standard	standard	NOUN
dti-1334	69	104	(	(	PUNCT
dti-1334	69	105	shaw	shaw	PROPN
dti-1334	69	106	et	et	PROPN
dti-1334	69	107	al	al	PROPN
dti-1334	69	108	.	.	PROPN
dti-1334	69	109	2003	2003	NUM
dti-1334	69	110	)	)	PUNCT
dti-1334	69	111	.	.	PUNCT
dti-1334	70	1	multidimensional	multidimensional	ADJ
dti-1334	70	2	protein	protein	NOUN
dti-1334	70	3	identifi	identifi	PROPN
dti-1334	70	4	cation	cation	NOUN
dti-1334	70	5	technology	technology	NOUN
dti-1334	70	6	(	(	PUNCT
dti-1334	70	7	mudpit	mudpit	NOUN
dti-1334	70	8	)	)	PUNCT
dti-1334	70	9	mudpit	mudpit	NOUN
dti-1334	70	10	(	(	PUNCT
dti-1334	70	11	multidimensional	multidimensional	ADJ
dti-1334	70	12	protein	protein	NOUN
dti-1334	70	13	identifi	identifi	PROPN
dti-1334	70	14	cation	cation	NOUN
dti-1334	70	15	technology	technology	NOUN
dti-1334	70	16	)	)	PUNCT
dti-1334	70	17	is	be	AUX
dti-1334	70	18	a	a	DET
dti-1334	70	19	non	non	ADJ
dti-1334	70	20	-	-	ADJ
dti-1334	70	21	gel	gel	ADJ
dti-1334	70	22	approach	approach	NOUN
dti-1334	70	23	to	to	ADP
dti-1334	70	24	the	the	DET
dti-1334	70	25	identifi	identifi	PROPN
dti-1334	70	26	cation	cation	NOUN
dti-1334	70	27	of	of	ADP
dti-1334	70	28	proteins	protein	NOUN
dti-1334	70	29	from	from	ADP
dti-1334	70	30	complex	complex	ADJ
dti-1334	70	31	mixtures	mixture	NOUN
dti-1334	70	32	(	(	PUNCT
dti-1334	70	33	kislinger	kislinger	PROPN
dti-1334	70	34	et	et	PROPN
dti-1334	70	35	al	al	PROPN
dti-1334	70	36	.	.	PROPN
dti-1334	70	37	2005	2005	NUM
dti-1334	70	38	)	)	PUNCT
dti-1334	70	39	.	.	PUNCT
dti-1334	71	1	it	it	PRON
dti-1334	71	2	offsets	offset	VERB
dti-1334	71	3	many	many	ADJ
dti-1334	71	4	of	of	ADP
dti-1334	71	5	the	the	DET
dti-1334	71	6	disadvantages	disadvantage	NOUN
dti-1334	71	7	associated	associate	VERB
dti-1334	71	8	with	with	ADP
dti-1334	71	9	two	two	NUM
dti-1334	71	10	-	-	PUNCT
dti-1334	71	11	dimensional	dimensional	ADJ
dti-1334	71	12	gel	gel	NOUN
dti-1334	71	13	electrophoresis	electrophoresis	NOUN
dti-1334	71	14	.	.	PUNCT
dti-1334	72	1	mudpit	mudpit	PROPN
dti-1334	72	2	uses	use	VERB
dti-1334	72	3	two	two	NUM
dti-1334	72	4	liquid	liquid	ADJ
dti-1334	72	5	chromatography	chromatography	NOUN
dti-1334	72	6	steps	step	NOUN
dti-1334	72	7	interfaced	interface	VERB
dti-1334	72	8	back	back	ADP
dti-1334	72	9	-	-	PUNCT
dti-1334	72	10	to	to	ADP
dti-1334	72	11	-	-	PUNCT
dti-1334	72	12	back	back	NOUN
dti-1334	72	13	in	in	ADP
dti-1334	72	14	a	a	DET
dti-1334	72	15	fused	fuse	VERB
dti-1334	72	16	silica	silica	NOUN
dti-1334	72	17	capillary	capillary	ADJ
dti-1334	72	18	to	to	PART
dti-1334	72	19	permit	permit	VERB
dti-1334	72	20	two	two	NUM
dti-1334	72	21	-	-	PUNCT
dti-1334	72	22	dimensional	dimensional	ADJ
dti-1334	72	23	high	high	ADJ
dti-1334	72	24	performance	performance	NOUN
dti-1334	72	25	liquid	liquid	NOUN
dti-1334	72	26	chromatography	chromatography	NOUN
dti-1334	72	27	(	(	PUNCT
dti-1334	72	28	breci	breci	NOUN
dti-1334	72	29	and	and	CCONJ
dti-1334	72	30	haynes	hayne	NOUN
dti-1334	72	31	,	,	PUNCT
dti-1334	72	32	2007	2007	NUM
dti-1334	72	33	)	)	PUNCT
dti-1334	72	34	.	.	PUNCT
dti-1334	73	1	typically	typically	ADV
dti-1334	73	2	,	,	PUNCT
dti-1334	73	3	the	the	DET
dti-1334	73	4	fi	fi	NOUN
dti-1334	73	5	rst	rst	NOUN
dti-1334	73	6	column	column	NOUN
dti-1334	73	7	containing	contain	VERB
dti-1334	73	8	a	a	DET
dti-1334	73	9	strong	strong	ADJ
dti-1334	73	10	cation	cation	NOUN
dti-1334	73	11	exchange	exchange	NOUN
dti-1334	73	12	(	(	PUNCT
dti-1334	73	13	scx	scx	NOUN
dti-1334	73	14	)	)	PUNCT
dti-1334	73	15	material	material	NOUN
dti-1334	73	16	is	be	AUX
dti-1334	73	17	coupled	couple	VERB
dti-1334	73	18	to	to	ADP
dti-1334	73	19	the	the	DET
dti-1334	73	20	second	second	ADJ
dti-1334	73	21	column	column	NOUN
dti-1334	73	22	containing	contain	VERB
dti-1334	73	23	reversed	reverse	VERB
dti-1334	73	24	phase	phase	NOUN
dti-1334	73	25	(	(	PUNCT
dti-1334	73	26	rp	rp	NOUN
dti-1334	73	27	)	)	PUNCT
dti-1334	73	28	materials	material	NOUN
dti-1334	73	29	,	,	PUNCT
dti-1334	73	30	which	which	PRON
dti-1334	73	31	is	be	AUX
dti-1334	73	32	in	in	ADP
dti-1334	73	33	turn	turn	NOUN
dti-1334	73	34	connected	connect	VERB
dti-1334	73	35	to	to	ADP
dti-1334	73	36	a	a	DET
dti-1334	73	37	tandem	tandem	NOUN
dti-1334	73	38	mass	mass	NOUN
dti-1334	73	39	spectrometer	spectrometer	NOUN
dti-1334	73	40	(	(	PUNCT
dti-1334	73	41	ms	ms	PROPN
dti-1334	73	42	)	)	PUNCT
dti-1334	73	43	(	(	PUNCT
dti-1334	73	44	fig	fig	NOUN
dti-1334	73	45	.	.	PUNCT
dti-1334	73	46	1	1	NUM
dti-1334	73	47	)	)	PUNCT
dti-1334	73	48	.	.	PUNCT
dti-1334	74	1	by	by	ADP
dti-1334	74	2	exploiting	exploit	VERB
dti-1334	74	3	a	a	DET
dti-1334	74	4	peptide	peptide	NOUN
dti-1334	74	5	’s	’s	PART
dti-1334	74	6	unique	unique	ADJ
dti-1334	74	7	physical	physical	ADJ
dti-1334	74	8	properties	property	NOUN
dti-1334	74	9	of	of	ADP
dti-1334	74	10	charge	charge	NOUN
dti-1334	74	11	and	and	CCONJ
dti-1334	74	12	hydrophobicity	hydrophobicity	NOUN
dti-1334	74	13	,	,	PUNCT
dti-1334	74	14	complex	complex	ADJ
dti-1334	74	15	mixtures	mixture	NOUN
dti-1334	74	16	can	can	AUX
dti-1334	74	17	be	be	AUX
dti-1334	74	18	separated	separate	VERB
dti-1334	74	19	prior	prior	ADV
dti-1334	74	20	to	to	ADP
dti-1334	74	21	sequencing	sequence	VERB
dti-1334	74	22	by	by	ADP
dti-1334	74	23	mass	mass	ADJ
dti-1334	74	24	spectrometry	spectrometry	NOUN
dti-1334	74	25	.	.	PUNCT
dti-1334	75	1	a	a	DET
dti-1334	75	2	complex	complex	ADJ
dti-1334	75	3	peptide	peptide	NOUN
dti-1334	75	4	mixture	mixture	NOUN
dti-1334	75	5	generated	generate	VERB
dti-1334	75	6	from	from	ADP
dti-1334	75	7	protein	protein	NOUN
dti-1334	75	8	lysates	lysate	NOUN
dti-1334	75	9	is	be	AUX
dti-1334	75	10	loaded	load	VERB
dti-1334	75	11	onto	onto	ADP
dti-1334	75	12	the	the	DET
dti-1334	75	13	biphasic	biphasic	ADJ
dti-1334	75	14	columns	column	NOUN
dti-1334	75	15	(	(	PUNCT
dti-1334	75	16	florens	floren	NOUN
dti-1334	75	17	and	and	CCONJ
dti-1334	75	18	washburn	washburn	NOUN
dti-1334	75	19	,	,	PUNCT
dti-1334	75	20	2006	2006	NUM
dti-1334	75	21	)	)	PUNCT
dti-1334	75	22	.	.	PUNCT
dti-1334	76	1	sample	sample	NOUN
dti-1334	76	2	preparation	preparation	NOUN
dti-1334	76	3	is	be	AUX
dti-1334	76	4	relatively	relatively	ADV
dti-1334	76	5	straightforward	straightforward	ADJ
dti-1334	76	6	,	,	PUNCT
dti-1334	76	7	the	the	DET
dti-1334	76	8	samples	sample	NOUN
dti-1334	76	9	are	be	AUX
dti-1334	76	10	denatured	denature	VERB
dti-1334	76	11	,	,	PUNCT
dti-1334	76	12	the	the	DET
dti-1334	76	13	cysteines	cysteine	NOUN
dti-1334	76	14	reduced	reduce	VERB
dti-1334	76	15	and	and	CCONJ
dti-1334	76	16	alkylated	alkylate	VERB
dti-1334	76	17	and	and	CCONJ
dti-1334	76	18	the	the	DET
dti-1334	76	19	proteins	protein	NOUN
dti-1334	76	20	digested	digest	VERB
dti-1334	76	21	with	with	ADP
dti-1334	76	22	a	a	DET
dti-1334	76	23	protease	protease	NOUN
dti-1334	76	24	such	such	ADJ
dti-1334	76	25	as	as	ADP
dti-1334	76	26	trypsin	trypsin	NOUN
dti-1334	76	27	.	.	PUNCT
dti-1334	77	1	charged	charge	VERB
dti-1334	77	2	peptides	peptide	NOUN
dti-1334	77	3	bind	bind	VERB
dti-1334	77	4	to	to	ADP
dti-1334	77	5	the	the	DET
dti-1334	77	6	scx	scx	NOUN
dti-1334	77	7	column	column	NOUN
dti-1334	77	8	,	,	PUNCT
dti-1334	77	9	whereas	whereas	SCONJ
dti-1334	77	10	any	any	DET
dti-1334	77	11	uncharged	uncharged	ADJ
dti-1334	77	12	peptides	peptide	NOUN
dti-1334	77	13	pass	pass	VERB
dti-1334	77	14	through	through	ADP
dti-1334	77	15	and	and	CCONJ
dti-1334	77	16	bind	bind	VERB
dti-1334	77	17	to	to	ADP
dti-1334	77	18	a	a	DET
dti-1334	77	19	reverse	reverse	ADJ
dti-1334	77	20	phase	phase	NOUN
dti-1334	77	21	trap	trap	NOUN
dti-1334	77	22	column	column	NOUN
dti-1334	77	23	.	.	PUNCT
dti-1334	78	1	chromatography	chromatography	NOUN
dti-1334	78	2	proceeds	proceed	NOUN
dti-1334	78	3	in	in	ADP
dti-1334	78	4	steps	step	NOUN
dti-1334	78	5	with	with	ADP
dti-1334	78	6	increasing	increase	VERB
dti-1334	78	7	salt	salt	NOUN
dti-1334	78	8	concentration	concentration	NOUN
dti-1334	78	9	to	to	PART
dti-1334	78	10	release	release	VERB
dti-1334	78	11	proteins	protein	NOUN
dti-1334	78	12	from	from	ADP
dti-1334	78	13	the	the	DET
dti-1334	78	14	scx	scx	NOUN
dti-1334	78	15	resin	resin	NOUN
dti-1334	78	16	in	in	ADP
dti-1334	78	17	steps	step	NOUN
dti-1334	78	18	unto	unto	ADP
dti-1334	78	19	the	the	DET
dti-1334	78	20	rp	rp	NOUN
dti-1334	78	21	resin	resin	NOUN
dti-1334	78	22	.	.	PUNCT
dti-1334	79	1	a	a	DET
dti-1334	79	2	reversed	reverse	VERB
dti-1334	79	3	phase	phase	NOUN
dti-1334	79	4	gradient	gradient	NOUN
dti-1334	79	5	with	with	ADP
dti-1334	79	6	increasing	increase	VERB
dti-1334	79	7	hydrophobicity	hydrophobicity	NOUN
dti-1334	79	8	is	be	AUX
dti-1334	79	9	then	then	ADV
dti-1334	79	10	slowly	slowly	ADV
dti-1334	79	11	introduced	introduce	VERB
dti-1334	79	12	58	58	NUM
dti-1334	79	13	shen	shen	NOUN
dti-1334	79	14	et	et	PROPN
dti-1334	79	15	al	al	PROPN
dti-1334	79	16	drug	drug	PROPN
dti-1334	79	17	target	target	NOUN
dti-1334	79	18	insights	insight	NOUN
dti-1334	79	19	2008:3	2008:3	NUM
dti-1334	79	20	to	to	PART
dti-1334	79	21	progressively	progressively	ADV
dti-1334	79	22	elute	elute	VERB
dti-1334	79	23	peptides	peptide	NOUN
dti-1334	79	24	from	from	ADP
dti-1334	79	25	the	the	DET
dti-1334	79	26	rp	rp	NOUN
dti-1334	79	27	resin	resin	NOUN
dti-1334	79	28	into	into	ADP
dti-1334	79	29	the	the	DET
dti-1334	79	30	mass	mass	NOUN
dti-1334	79	31	spectrometer	spectrometer	NOUN
dti-1334	79	32	.	.	PUNCT
dti-1334	80	1	peptide	peptide	NOUN
dti-1334	80	2	fragmentation	fragmentation	NOUN
dti-1334	80	3	data	datum	NOUN
dti-1334	80	4	is	be	AUX
dti-1334	80	5	then	then	ADV
dti-1334	80	6	obtained	obtain	VERB
dti-1334	80	7	to	to	PART
dti-1334	80	8	identify	identify	VERB
dti-1334	80	9	the	the	DET
dti-1334	80	10	peptides	peptide	NOUN
dti-1334	80	11	and	and	CCONJ
dti-1334	80	12	hence	hence	ADV
dti-1334	80	13	the	the	DET
dti-1334	80	14	proteins	protein	NOUN
dti-1334	80	15	from	from	ADP
dti-1334	80	16	which	which	PRON
dti-1334	80	17	they	they	PRON
dti-1334	80	18	are	be	AUX
dti-1334	80	19	derived	derive	VERB
dti-1334	80	20	.	.	PUNCT
dti-1334	81	1	in	in	ADP
dti-1334	81	2	the	the	DET
dti-1334	81	3	next	next	ADJ
dti-1334	81	4	step	step	NOUN
dti-1334	81	5	,	,	PUNCT
dti-1334	81	6	a	a	DET
dti-1334	81	7	buffer	buffer	NOUN
dti-1334	81	8	with	with	ADP
dti-1334	81	9	increased	increase	VERB
dti-1334	81	10	salt	salt	NOUN
dti-1334	81	11	concentration	concentration	NOUN
dti-1334	81	12	is	be	AUX
dti-1334	81	13	injected	inject	VERB
dti-1334	81	14	onto	onto	ADP
dti-1334	81	15	the	the	DET
dti-1334	81	16	scx	scx	NOUN
dti-1334	81	17	column	column	NOUN
dti-1334	81	18	,	,	PUNCT
dti-1334	81	19	displacing	displace	VERB
dti-1334	81	20	further	further	ADJ
dti-1334	81	21	peptides	peptide	NOUN
dti-1334	81	22	from	from	ADP
dti-1334	81	23	it	it	PRON
dti-1334	81	24	onto	onto	ADP
dti-1334	81	25	the	the	DET
dti-1334	81	26	rp	rp	NOUN
dti-1334	81	27	trap	trap	NOUN
dti-1334	81	28	column	column	NOUN
dti-1334	81	29	.	.	PUNCT
dti-1334	82	1	salt	salt	NOUN
dti-1334	82	2	is	be	AUX
dti-1334	82	3	removed	remove	VERB
dti-1334	82	4	by	by	ADP
dti-1334	82	5	washing	wash	VERB
dti-1334	82	6	the	the	DET
dti-1334	82	7	column	column	NOUN
dti-1334	82	8	and	and	CCONJ
dti-1334	82	9	again	again	ADV
dti-1334	82	10	an	an	DET
dti-1334	82	11	analytical	analytical	ADJ
dti-1334	82	12	rp	rp	NOUN
dti-1334	82	13	separation	separation	NOUN
dti-1334	82	14	is	be	AUX
dti-1334	82	15	performed	perform	VERB
dti-1334	82	16	and	and	CCONJ
dti-1334	82	17	the	the	DET
dti-1334	82	18	eluting	eluting	NOUN
dti-1334	82	19	peptides	peptide	NOUN
dti-1334	82	20	analyzed	analyze	VERB
dti-1334	82	21	by	by	ADP
dti-1334	82	22	mass	mass	ADJ
dti-1334	82	23	spectrometry	spectrometry	NOUN
dti-1334	82	24	.	.	PUNCT
dti-1334	83	1	incremental	incremental	ADJ
dti-1334	83	2	increases	increase	NOUN
dti-1334	83	3	of	of	ADP
dti-1334	83	4	salt	salt	NOUN
dti-1334	83	5	are	be	AUX
dti-1334	83	6	used	use	VERB
dti-1334	83	7	(	(	PUNCT
dti-1334	83	8	salt	salt	NOUN
dti-1334	83	9	step	step	NOUN
dti-1334	83	10	gradient	gradient	NOUN
dti-1334	83	11	from	from	ADP
dti-1334	83	12	around	around	ADV
dti-1334	83	13	0–200	0–200	NUM
dti-1334	83	14	mm	mm	NOUN
dti-1334	83	15	)	)	PUNCT
dti-1334	83	16	.	.	PUNCT
dti-1334	84	1	the	the	DET
dti-1334	84	2	end	end	NOUN
dti-1334	84	3	result	result	NOUN
dti-1334	84	4	is	be	AUX
dti-1334	84	5	multiple	multiple	ADJ
dti-1334	84	6	protein	protein	NOUN
dti-1334	84	7	identifi	identifi	NOUN
dti-1334	84	8	cations	cation	NOUN
dti-1334	84	9	from	from	ADP
dti-1334	84	10	each	each	DET
dti-1334	84	11	salt	salt	NOUN
dti-1334	84	12	step	step	NOUN
dti-1334	84	13	(	(	PUNCT
dti-1334	84	14	wu	wu	PROPN
dti-1334	84	15	and	and	CCONJ
dti-1334	84	16	maccoss	maccoss	NOUN
dti-1334	84	17	,	,	PUNCT
dti-1334	84	18	2002	2002	NUM
dti-1334	84	19	)	)	PUNCT
dti-1334	84	20	.	.	PUNCT
dti-1334	85	1	the	the	DET
dti-1334	85	2	biphasic	biphasic	ADJ
dti-1334	85	3	column	column	NOUN
dti-1334	85	4	which	which	PRON
dti-1334	85	5	is	be	AUX
dti-1334	85	6	placed	place	VERB
dti-1334	85	7	in	in	ADP
dti-1334	85	8	-	-	PUNCT
dti-1334	85	9	line	line	NOUN
dti-1334	85	10	with	with	ADP
dti-1334	85	11	the	the	DET
dti-1334	85	12	hplc	hplc	NOUN
dti-1334	85	13	system	system	NOUN
dti-1334	85	14	acts	act	VERB
dti-1334	85	15	as	as	ADP
dti-1334	85	16	an	an	DET
dti-1334	85	17	ion	ion	NOUN
dti-1334	85	18	source	source	NOUN
dti-1334	85	19	for	for	ADP
dti-1334	85	20	tandem	tandem	PROPN
dti-1334	85	21	ms	ms	PROPN
dti-1334	85	22	.	.	PROPN
dti-1334	86	1	this	this	DET
dti-1334	86	2	design	design	NOUN
dti-1334	86	3	reduces	reduce	VERB
dti-1334	86	4	dead	dead	ADJ
dti-1334	86	5	volumes	volume	NOUN
dti-1334	86	6	and	and	CCONJ
dti-1334	86	7	band	band	NOUN
dti-1334	86	8	broadening	broaden	VERB
dti-1334	86	9	,	,	PUNCT
dti-1334	86	10	thereby	thereby	ADV
dti-1334	86	11	maximizing	maximize	VERB
dti-1334	86	12	resolution	resolution	NOUN
dti-1334	86	13	and	and	CCONJ
dti-1334	86	14	sensitivity	sensitivity	NOUN
dti-1334	86	15	.	.	PUNCT
dti-1334	87	1	isotope	isotope	NOUN
dti-1334	87	2	coded	code	VERB
dti-1334	87	3	affi	affi	PROPN
dti-1334	87	4	nity	nity	NOUN
dti-1334	87	5	tags	tag	NOUN
dti-1334	87	6	(	(	PUNCT
dti-1334	87	7	icat	icat	NOUN
dti-1334	87	8	)	)	PUNCT
dti-1334	87	9	chemical	chemical	NOUN
dti-1334	87	10	tagging	tagging	NOUN
dti-1334	87	11	(	(	PUNCT
dti-1334	87	12	usually	usually	ADV
dti-1334	87	13	stable	stable	ADJ
dti-1334	87	14	isotope	isotope	NOUN
dti-1334	87	15	labeling	labeling	NOUN
dti-1334	87	16	)	)	PUNCT
dti-1334	87	17	of	of	ADP
dti-1334	87	18	proteins	protein	NOUN
dti-1334	87	19	/	/	SYM
dti-1334	87	20	peptides	peptide	NOUN
dti-1334	87	21	allows	allow	VERB
dti-1334	87	22	for	for	ADP
dti-1334	87	23	relative	relative	ADJ
dti-1334	87	24	quantifi	quantifi	ADJ
dti-1334	87	25	cation	cation	NOUN
dti-1334	87	26	of	of	ADP
dti-1334	87	27	protein	protein	NOUN
dti-1334	87	28	samples	sample	NOUN
dti-1334	87	29	by	by	ADP
dti-1334	87	30	liquid	liquid	ADJ
dti-1334	87	31	chromatography	chromatography	NOUN
dti-1334	87	32	/	/	SYM
dti-1334	87	33	mass	mass	NOUN
dti-1334	87	34	spectrometry	spectrometry	NOUN
dti-1334	87	35	(	(	PUNCT
dti-1334	87	36	lc	lc	PROPN
dti-1334	87	37	-	-	PUNCT
dti-1334	87	38	ms	ms	NOUN
dti-1334	87	39	)	)	PUNCT
dti-1334	87	40	analyses	analysis	NOUN
dti-1334	87	41	.	.	PUNCT
dti-1334	88	1	the	the	DET
dti-1334	88	2	prototypical	prototypical	ADJ
dti-1334	88	3	stable	stable	ADJ
dti-1334	88	4	-	-	PUNCT
dti-1334	88	5	isotope	isotope	NOUN
dti-1334	88	6	labeling	labeling	NOUN
dti-1334	88	7	for	for	ADP
dti-1334	88	8	quantitative	quantitative	ADJ
dti-1334	88	9	proteomics	proteomic	NOUN
dti-1334	88	10	was	be	AUX
dti-1334	88	11	isotope	isotope	NOUN
dti-1334	88	12	-	-	PUNCT
dti-1334	88	13	coded	code	VERB
dti-1334	88	14	affi	affi	PROPN
dti-1334	88	15	nity	nity	NOUN
dti-1334	88	16	tags	tag	NOUN
dti-1334	88	17	(	(	PUNCT
dti-1334	88	18	icat	icat	NOUN
dti-1334	88	19	)	)	PUNCT
dti-1334	88	20	technology	technology	NOUN
dti-1334	88	21	.	.	PUNCT
dti-1334	89	1	developed	develop	VERB
dti-1334	89	2	in	in	ADP
dti-1334	89	3	the	the	DET
dti-1334	89	4	laboratory	laboratory	NOUN
dti-1334	89	5	of	of	ADP
dti-1334	89	6	dr	dr	PROPN
dti-1334	89	7	.	.	PROPN
dti-1334	89	8	reudi	reudi	PROPN
dti-1334	89	9	aebersold	aebersold	PROPN
dti-1334	89	10	,	,	PUNCT
dti-1334	89	11	this	this	DET
dti-1334	89	12	technology	technology	NOUN
dti-1334	89	13	simultaneously	simultaneously	ADV
dti-1334	89	14	quantifi	quantifi	ADJ
dti-1334	89	15	es	es	NOUN
dti-1334	89	16	and	and	CCONJ
dti-1334	89	17	identifi	identifi	NOUN
dti-1334	89	18	es	es	ADP
dti-1334	89	19	protein	protein	NOUN
dti-1334	89	20	differences	difference	NOUN
dti-1334	89	21	in	in	ADP
dti-1334	89	22	paired	pair	VERB
dti-1334	89	23	samples	sample	NOUN
dti-1334	89	24	(	(	PUNCT
dti-1334	89	25	gygi	gygi	NOUN
dti-1334	89	26	et	et	PROPN
dti-1334	89	27	al	al	PROPN
dti-1334	89	28	.	.	PROPN
dti-1334	89	29	1999	1999	NUM
dti-1334	89	30	)	)	PUNCT
dti-1334	89	31	.	.	PUNCT
dti-1334	90	1	essentially	essentially	ADV
dti-1334	90	2	,	,	PUNCT
dti-1334	90	3	proteins	protein	NOUN
dti-1334	90	4	from	from	ADP
dti-1334	90	5	the	the	DET
dti-1334	90	6	two	two	NUM
dti-1334	90	7	states	state	NOUN
dti-1334	90	8	to	to	PART
dti-1334	90	9	be	be	AUX
dti-1334	90	10	compared	compare	VERB
dti-1334	90	11	are	be	AUX
dti-1334	90	12	labeled	label	VERB
dti-1334	90	13	at	at	ADP
dti-1334	90	14	cysteine	cysteine	NOUN
dti-1334	90	15	residues	residue	NOUN
dti-1334	90	16	with	with	ADP
dti-1334	90	17	light	light	NOUN
dti-1334	90	18	and	and	CCONJ
dti-1334	90	19	heavy	heavy	ADJ
dti-1334	90	20	tags	tag	NOUN
dti-1334	90	21	,	,	PUNCT
dti-1334	90	22	respectively	respectively	ADV
dti-1334	90	23	.	.	PUNCT
dti-1334	91	1	like	like	ADP
dti-1334	91	2	the	the	DET
dti-1334	91	3	cyanine	cyanine	NOUN
dti-1334	91	4	dyes	dye	NOUN
dti-1334	91	5	used	use	VERB
dti-1334	91	6	in	in	ADP
dti-1334	91	7	2	2	NUM
dti-1334	91	8	-	-	PUNCT
dti-1334	91	9	d	d	NOUN
dti-1334	91	10	dige	dige	NOUN
dti-1334	91	11	,	,	PUNCT
dti-1334	91	12	the	the	DET
dti-1334	91	13	isotopic	isotopic	ADJ
dti-1334	91	14	tags	tag	NOUN
dti-1334	91	15	are	be	AUX
dti-1334	91	16	similar	similar	ADJ
dti-1334	91	17	in	in	ADP
dti-1334	91	18	structure	structure	NOUN
dti-1334	91	19	and	and	CCONJ
dti-1334	91	20	chemical	chemical	NOUN
dti-1334	91	21	properties	property	NOUN
dti-1334	91	22	,	,	PUNCT
dti-1334	91	23	but	but	CCONJ
dti-1334	91	24	are	be	AUX
dti-1334	91	25	different	different	ADJ
dti-1334	91	26	in	in	ADP
dti-1334	91	27	mass	mass	PROPN
dti-1334	91	28	.	.	PUNCT
dti-1334	92	1	the	the	DET
dti-1334	92	2	icat	icat	NOUN
dti-1334	92	3	reagents	reagent	NOUN
dti-1334	92	4	consist	consist	VERB
dti-1334	92	5	of	of	ADP
dti-1334	92	6	three	three	NUM
dti-1334	92	7	functional	functional	ADJ
dti-1334	92	8	elements	element	NOUN
dti-1334	92	9	:	:	PUNCT
dti-1334	92	10	a	a	DET
dti-1334	92	11	cleavable	cleavable	ADJ
dti-1334	92	12	biotin	biotin	NOUN
dti-1334	92	13	group	group	NOUN
dti-1334	92	14	,	,	PUNCT
dti-1334	92	15	an	an	DET
dti-1334	92	16	isotopic	isotopic	ADJ
dti-1334	92	17	tag	tag	NOUN
dti-1334	92	18	that	that	PRON
dti-1334	92	19	occurs	occur	VERB
dti-1334	92	20	in	in	ADP
dti-1334	92	21	a	a	DET
dti-1334	92	22	“	"	PUNCT
dti-1334	92	23	heavy	heavy	ADJ
dti-1334	92	24	”	"	PUNCT
dti-1334	92	25	or	or	CCONJ
dti-1334	92	26	“	"	PUNCT
dti-1334	92	27	light	light	ADJ
dti-1334	92	28	”	"	PUNCT
dti-1334	92	29	state	state	NOUN
dti-1334	92	30	,	,	PUNCT
dti-1334	92	31	and	and	CCONJ
dti-1334	92	32	a	a	DET
dti-1334	92	33	cysteine	cysteine	ADJ
dti-1334	92	34	-	-	PUNCT
dti-1334	92	35	reactive	reactive	ADJ
dti-1334	92	36	group	group	NOUN
dti-1334	92	37	.	.	PUNCT
dti-1334	93	1	two	two	NUM
dti-1334	93	2	proteins	protein	NOUN
dti-1334	93	3	samples	sample	NOUN
dti-1334	93	4	are	be	AUX
dti-1334	93	5	separately	separately	ADV
dti-1334	93	6	labeled	label	VERB
dti-1334	93	7	using	use	VERB
dti-1334	93	8	the	the	DET
dti-1334	93	9	heavy	heavy	ADJ
dti-1334	93	10	(	(	PUNCT
dti-1334	93	11	deuterated	deuterate	VERB
dti-1334	93	12	or	or	CCONJ
dti-1334	93	13	13c	13c	NOUN
dti-1334	93	14	)	)	PUNCT
dti-1334	93	15	icat	icat	NOUN
dti-1334	93	16	reagent	reagent	NOUN
dti-1334	93	17	for	for	ADP
dti-1334	93	18	one	one	NUM
dti-1334	93	19	protein	protein	NOUN
dti-1334	93	20	sample	sample	NOUN
dti-1334	93	21	and	and	CCONJ
dti-1334	93	22	the	the	DET
dti-1334	93	23	light	light	NOUN
dti-1334	93	24	(	(	PUNCT
dti-1334	93	25	non	non	ADJ
dti-1334	93	26	-	-	ADJ
dti-1334	93	27	deuterated	deuterated	ADJ
dti-1334	93	28	or	or	CCONJ
dti-1334	93	29	12c	12c	NUM
dti-1334	93	30	)	)	PUNCT
dti-1334	93	31	icat	icat	NOUN
dti-1334	93	32	reagent	reagent	ADJ
dti-1334	93	33	for	for	ADP
dti-1334	93	34	the	the	DET
dti-1334	93	35	other	other	ADJ
dti-1334	93	36	(	(	PUNCT
dti-1334	93	37	han	han	PROPN
dti-1334	93	38	et	et	PROPN
dti-1334	93	39	al	al	PROPN
dti-1334	93	40	.	.	PROPN
dti-1334	93	41	2001	2001	NUM
dti-1334	93	42	)	)	PUNCT
dti-1334	93	43	.	.	PUNCT
dti-1334	94	1	the	the	DET
dti-1334	94	2	two	two	NUM
dti-1334	94	3	labeled	label	VERB
dti-1334	94	4	mixtures	mixture	NOUN
dti-1334	94	5	are	be	AUX
dti-1334	94	6	then	then	ADV
dti-1334	94	7	combined	combine	VERB
dti-1334	94	8	,	,	PUNCT
dti-1334	94	9	proteolytically	proteolytically	ADV
dti-1334	94	10	digested	digest	VERB
dti-1334	94	11	and	and	CCONJ
dti-1334	94	12	run	run	VERB
dti-1334	94	13	on	on	ADP
dti-1334	94	14	an	an	DET
dti-1334	94	15	avidin	avidin	NOUN
dti-1334	94	16	column	column	NOUN
dti-1334	94	17	to	to	PART
dti-1334	94	18	pull	pull	VERB
dti-1334	94	19	out	out	ADV
dti-1334	94	20	only	only	ADV
dti-1334	94	21	the	the	DET
dti-1334	94	22	labeled	label	VERB
dti-1334	94	23	peptides	peptide	NOUN
dti-1334	94	24	via	via	ADP
dti-1334	94	25	the	the	DET
dti-1334	94	26	biotin	biotin	NOUN
dti-1334	94	27	tag	tag	NOUN
dti-1334	94	28	.	.	PUNCT
dti-1334	95	1	this	this	PRON
dti-1334	95	2	reduces	reduce	VERB
dti-1334	95	3	the	the	DET
dti-1334	95	4	complexity	complexity	NOUN
dti-1334	95	5	of	of	ADP
dti-1334	95	6	the	the	DET
dti-1334	95	7	sample	sample	NOUN
dti-1334	95	8	prior	prior	ADV
dti-1334	95	9	to	to	ADP
dti-1334	95	10	analysis	analysis	NOUN
dti-1334	95	11	by	by	ADP
dti-1334	95	12	nano	nano	NOUN
dti-1334	95	13	-	-	PUNCT
dti-1334	95	14	scale	scale	NOUN
dti-1334	95	15	lc	lc	PROPN
dti-1334	95	16	-	-	PUNCT
dti-1334	95	17	ms	ms	PROPN
dti-1334	95	18	/	/	SYM
dti-1334	95	19	ms	ms	PROPN
dti-1334	95	20	(	(	PUNCT
dti-1334	95	21	shiio	shiio	NOUN
dti-1334	95	22	and	and	CCONJ
dti-1334	95	23	aebersold	aebersold	NOUN
dti-1334	95	24	,	,	PUNCT
dti-1334	95	25	2006	2006	NUM
dti-1334	95	26	)	)	PUNCT
dti-1334	95	27	.	.	PUNCT
dti-1334	96	1	peaks	peak	NOUN
dti-1334	96	2	corresponding	correspond	VERB
dti-1334	96	3	to	to	ADP
dti-1334	96	4	the	the	DET
dti-1334	96	5	same	same	ADJ
dti-1334	96	6	peptide	peptide	NOUN
dti-1334	96	7	are	be	AUX
dti-1334	96	8	identifi	identifi	NOUN
dti-1334	96	9	ed	ed	NOUN
dti-1334	96	10	as	as	ADP
dti-1334	96	11	doublets	doublet	NOUN
dti-1334	96	12	in	in	ADP
dti-1334	96	13	mass	mass	ADJ
dti-1334	96	14	spectra	spectra	NOUN
dti-1334	96	15	due	due	ADP
dti-1334	96	16	to	to	ADP
dti-1334	96	17	the	the	DET
dti-1334	96	18	mass	mass	ADJ
dti-1334	96	19	difference	difference	NOUN
dti-1334	96	20	between	between	ADP
dti-1334	96	21	light	light	NOUN
dti-1334	96	22	and	and	CCONJ
dti-1334	96	23	heavy	heavy	ADJ
dti-1334	96	24	isotopes	isotope	NOUN
dti-1334	96	25	.	.	PUNCT
dti-1334	97	1	the	the	DET
dti-1334	97	2	peak	peak	NOUN
dti-1334	97	3	intensities	intensity	NOUN
dti-1334	97	4	of	of	ADP
dti-1334	97	5	the	the	DET
dti-1334	97	6	peptides	peptide	NOUN
dti-1334	97	7	correlate	correlate	VERB
dti-1334	97	8	directly	directly	ADV
dti-1334	97	9	with	with	ADP
dti-1334	97	10	the	the	DET
dti-1334	97	11	relative	relative	ADJ
dti-1334	97	12	abundance	abundance	NOUN
dti-1334	97	13	of	of	ADP
dti-1334	97	14	the	the	DET
dti-1334	97	15	proteins	protein	NOUN
dti-1334	97	16	in	in	ADP
dti-1334	97	17	the	the	DET
dti-1334	97	18	two	two	NUM
dti-1334	97	19	states	state	NOUN
dti-1334	97	20	.	.	PUNCT
dti-1334	98	1	selected	select	VERB
dti-1334	98	2	peptides	peptide	NOUN
dti-1334	98	3	(	(	PUNCT
dti-1334	98	4	usually	usually	ADV
dti-1334	98	5	those	those	PRON
dti-1334	98	6	that	that	PRON
dti-1334	98	7	show	show	VERB
dti-1334	98	8	a	a	DET
dti-1334	98	9	signifi	signifi	NOUN
dti-1334	98	10	ca	can	AUX
dti-1334	98	11	nt	not	PART
dti-1334	98	12	difference	difference	VERB
dti-1334	98	13	in	in	ADP
dti-1334	98	14	abundance	abundance	NOUN
dti-1334	98	15	between	between	ADP
dti-1334	98	16	the	the	DET
dti-1334	98	17	two	two	NUM
dti-1334	98	18	samples	sample	NOUN
dti-1334	98	19	)	)	PUNCT
dti-1334	98	20	will	will	AUX
dti-1334	98	21	be	be	AUX
dti-1334	98	22	subjected	subject	VERB
dti-1334	98	23	to	to	ADP
dti-1334	98	24	ms	ms	PROPN
dti-1334	98	25	/	/	SYM
dti-1334	98	26	ms	ms	NOUN
dti-1334	98	27	analysis	analysis	NOUN
dti-1334	98	28	to	to	PART
dti-1334	98	29	reveal	reveal	VERB
dti-1334	98	30	the	the	DET
dti-1334	98	31	amino	amino	NOUN
dti-1334	98	32	acid	acid	NOUN
dti-1334	98	33	sequence	sequence	NOUN
dti-1334	98	34	and	and	CCONJ
dti-1334	98	35	thus	thus	ADV
dti-1334	98	36	the	the	DET
dti-1334	98	37	protein	protein	NOUN
dti-1334	98	38	identity	identity	NOUN
dti-1334	98	39	(	(	PUNCT
dti-1334	98	40	tannu	tannu	NOUN
dti-1334	98	41	and	and	CCONJ
dti-1334	98	42	hemby	hemby	NOUN
dti-1334	98	43	,	,	PUNCT
dti-1334	98	44	2006a	2006a	NUM
dti-1334	98	45	;	;	PUNCT
dti-1334	98	46	turecek	turecek	NUM
dti-1334	98	47	,	,	PUNCT
dti-1334	98	48	2002	2002	NUM
dti-1334	98	49	)	)	PUNCT
dti-1334	98	50	.	.	PUNCT
dti-1334	99	1	icat	icat	NOUN
dti-1334	99	2	is	be	AUX
dti-1334	99	3	a	a	DET
dti-1334	99	4	powerful	powerful	ADJ
dti-1334	99	5	protein	protein	NOUN
dti-1334	99	6	profi	profi	PROPN
dti-1334	99	7	ling	ling	PROPN
dti-1334	99	8	technology	technology	NOUN
dti-1334	99	9	that	that	PRON
dti-1334	99	10	al	al	PROPN
dti-1334	99	11	lows	low	VERB
dti-1334	99	12	simultaneous	simultaneous	ADJ
dti-1334	99	13	detect	detect	NOUN
dti-1334	99	14	ion	ion	NOUN
dti-1334	99	15	and	and	CCONJ
dti-1334	99	16	figure	figure	NOUN
dti-1334	99	17	1	1	NUM
dti-1334	99	18	.	.	PUNCT
dti-1334	100	1	summary	summary	NOUN
dti-1334	100	2	of	of	ADP
dti-1334	100	3	steps	step	NOUN
dti-1334	100	4	utilized	utilize	VERB
dti-1334	100	5	by	by	ADP
dti-1334	100	6	multidimensional	multidimensional	ADJ
dti-1334	100	7	protein	protein	NOUN
dti-1334	100	8	identifi	identifi	PROPN
dti-1334	100	9	cation	cation	NOUN
dti-1334	100	10	technology	technology	NOUN
dti-1334	100	11	(	(	PUNCT
dti-1334	100	12	mudpit	mudpit	NOUN
dti-1334	100	13	)	)	PUNCT
dti-1334	100	14	.	.	PUNCT
dti-1334	101	1	scx	scx	NOUN
dti-1334	101	2	=	=	PUNCT
dti-1334	101	3	strong	strong	ADJ
dti-1334	101	4	cation	cation	NOUN
dti-1334	101	5	exchange	exchange	NOUN
dti-1334	101	6	;	;	PUNCT
dti-1334	101	7	rp	rp	NOUN
dti-1334	101	8	=	=	NUM
dti-1334	101	9	reversed	reverse	VERB
dti-1334	101	10	phase	phase	NOUN
dti-1334	101	11	.	.	PUNCT
dti-1334	102	1	59	59	NUM
dti-1334	102	2	proteomics	proteomic	NOUN
dti-1334	102	3	in	in	ADP
dti-1334	102	4	personalized	personalized	ADJ
dti-1334	102	5	cancer	cancer	NOUN
dti-1334	102	6	therapy	therapy	NOUN
dti-1334	102	7	drug	drug	NOUN
dti-1334	102	8	target	target	NOUN
dti-1334	102	9	insights	insight	VERB
dti-1334	102	10	2008:3	2008:3	NUM
dti-1334	102	11	quantification	quantification	NOUN
dti-1334	102	12	of	of	ADP
dti-1334	102	13	protein	protein	NOUN
dti-1334	102	14	differences	difference	NOUN
dti-1334	102	15	between	between	ADP
dti-1334	102	16	biological	biological	ADJ
dti-1334	102	17	samples	sample	NOUN
dti-1334	102	18	as	as	ADV
dti-1334	102	19	well	well	ADV
dti-1334	102	20	as	as	ADP
dti-1334	102	21	identifi	identifi	PROPN
dti-1334	102	22	cation	cation	NOUN
dti-1334	102	23	of	of	ADP
dti-1334	102	24	the	the	DET
dti-1334	102	25	proteins	protein	NOUN
dti-1334	102	26	.	.	PUNCT
dti-1334	103	1	icat	icat	NOUN
dti-1334	103	2	has	have	VERB
dti-1334	103	3	the	the	DET
dti-1334	103	4	power	power	NOUN
dti-1334	103	5	to	to	PART
dti-1334	103	6	quantitatively	quantitatively	ADV
dti-1334	103	7	identify	identify	VERB
dti-1334	103	8	proteins	protein	NOUN
dti-1334	103	9	including	include	VERB
dti-1334	103	10	acidic	acidic	ADJ
dti-1334	103	11	and	and	CCONJ
dti-1334	103	12	basic	basic	ADJ
dti-1334	103	13	proteins	protein	NOUN
dti-1334	103	14	,	,	PUNCT
dti-1334	103	15	membrane	membrane	NOUN
dti-1334	103	16	proteins	protein	NOUN
dti-1334	103	17	,	,	PUNCT
dti-1334	103	18	low	low	ADJ
dti-1334	103	19	copy	copy	NOUN
dti-1334	103	20	number	number	NOUN
dti-1334	103	21	proteins	protein	NOUN
dti-1334	103	22	,	,	PUNCT
dti-1334	103	23	and	and	CCONJ
dti-1334	103	24	high	high	ADJ
dti-1334	103	25	molecular	molecular	ADJ
dti-1334	103	26	weight	weight	NOUN
dti-1334	103	27	proteins	protein	NOUN
dti-1334	103	28	(	(	PUNCT
dti-1334	103	29	griffi	griffi	NOUN
dti-1334	103	30	n	n	VERB
dti-1334	103	31	et	et	PROPN
dti-1334	103	32	al	al	PROPN
dti-1334	103	33	.	.	PROPN
dti-1334	103	34	2003	2003	NUM
dti-1334	103	35	;	;	PUNCT
dti-1334	103	36	smolka	smolka	VERB
dti-1334	103	37	et	et	PROPN
dti-1334	103	38	al	al	PROPN
dti-1334	103	39	.	.	PROPN
dti-1334	103	40	2001	2001	NUM
dti-1334	103	41	)	)	PUNCT
dti-1334	103	42	.	.	PUNCT
dti-1334	104	1	the	the	DET
dti-1334	104	2	weaknesses	weakness	NOUN
dti-1334	104	3	of	of	ADP
dti-1334	104	4	icat	icat	NOUN
dti-1334	104	5	include	include	VERB
dti-1334	104	6	(	(	PUNCT
dti-1334	104	7	ciordia	ciordia	PROPN
dti-1334	104	8	et	et	PROPN
dti-1334	104	9	al	al	PROPN
dti-1334	104	10	.	.	PROPN
dti-1334	104	11	2006	2006	NUM
dti-1334	104	12	;	;	PUNCT
dti-1334	104	13	tannu	tannu	NOUN
dti-1334	104	14	and	and	CCONJ
dti-1334	104	15	hemby	hemby	NOUN
dti-1334	104	16	,	,	PUNCT
dti-1334	104	17	2006a	2006a	NUM
dti-1334	104	18	):	):	PUNCT
dti-1334	104	19	1	1	NUM
dti-1334	104	20	)	)	PUNCT
dti-1334	104	21	proteins	protein	NOUN
dti-1334	104	22	that	that	PRON
dti-1334	104	23	do	do	AUX
dti-1334	104	24	not	not	PART
dti-1334	104	25	contain	contain	VERB
dti-1334	104	26	cysteine	cysteine	ADJ
dti-1334	104	27	,	,	PUNCT
dti-1334	104	28	or	or	CCONJ
dti-1334	104	29	proteins	protein	NOUN
dti-1334	104	30	that	that	PRON
dti-1334	104	31	do	do	AUX
dti-1334	104	32	not	not	PART
dti-1334	104	33	contain	contain	VERB
dti-1334	104	34	cysteine	cysteine	NOUN
dti-1334	104	35	residues	residue	NOUN
dti-1334	104	36	on	on	ADP
dti-1334	104	37	tractable	tractable	ADJ
dti-1334	104	38	peptides	peptide	NOUN
dti-1334	104	39	upon	upon	SCONJ
dti-1334	104	40	proteolytic	proteolytic	ADJ
dti-1334	104	41	digestion	digestion	NOUN
dti-1334	104	42	,	,	PUNCT
dti-1334	104	43	will	will	AUX
dti-1334	104	44	not	not	PART
dti-1334	104	45	be	be	AUX
dti-1334	104	46	detected	detect	VERB
dti-1334	104	47	due	due	ADP
dti-1334	104	48	to	to	ADP
dti-1334	104	49	the	the	DET
dti-1334	104	50	nature	nature	NOUN
dti-1334	104	51	of	of	ADP
dti-1334	104	52	the	the	DET
dti-1334	104	53	labeling	labeling	NOUN
dti-1334	104	54	procedure	procedure	NOUN
dti-1334	104	55	(	(	PUNCT
dti-1334	104	56	moseley	moseley	NOUN
dti-1334	104	57	,	,	PUNCT
dti-1334	104	58	2001	2001	NUM
dti-1334	104	59	)	)	PUNCT
dti-1334	104	60	.	.	PUNCT
dti-1334	105	1	2	2	X
dti-1334	105	2	)	)	PUNCT
dti-1334	105	3	high	high	ADJ
dti-1334	105	4	sample	sample	NOUN
dti-1334	105	5	complexity	complexity	NOUN
dti-1334	105	6	and	and	CCONJ
dti-1334	105	7	the	the	DET
dti-1334	105	8	data	data	NOUN
dti-1334	105	9	-	-	PUNCT
dti-1334	105	10	acquisition	acquisition	NOUN
dti-1334	105	11	rate	rate	NOUN
dti-1334	105	12	of	of	ADP
dti-1334	105	13	the	the	DET
dti-1334	105	14	mass	mass	NOUN
dti-1334	105	15	spectrometer	spectrometer	NOUN
dti-1334	105	16	used	use	VERB
dti-1334	105	17	may	may	AUX
dti-1334	105	18	limit	limit	VERB
dti-1334	105	19	coverage	coverage	NOUN
dti-1334	105	20	of	of	ADP
dti-1334	105	21	differentially	differentially	ADV
dti-1334	105	22	expressed	express	VERB
dti-1334	105	23	proteins	protein	NOUN
dti-1334	105	24	(	(	PUNCT
dti-1334	105	25	moseley	moseley	NOUN
dti-1334	105	26	,	,	PUNCT
dti-1334	105	27	2001	2001	NUM
dti-1334	105	28	)	)	PUNCT
dti-1334	105	29	.	.	PUNCT
dti-1334	106	1	3	3	X
dti-1334	106	2	)	)	PUNCT
dti-1334	106	3	the	the	DET
dti-1334	106	4	number	number	NOUN
dti-1334	106	5	of	of	ADP
dti-1334	106	6	proteins	protein	NOUN
dti-1334	106	7	that	that	PRON
dti-1334	106	8	can	can	AUX
dti-1334	106	9	be	be	AUX
dti-1334	106	10	identifi	identifi	PROPN
dti-1334	106	11	ed	ed	NOUN
dti-1334	106	12	in	in	ADP
dti-1334	106	13	an	an	DET
dti-1334	106	14	icat	icat	NOUN
dti-1334	106	15	experiment	experiment	NOUN
dti-1334	106	16	(	(	PUNCT
dti-1334	106	17	resolution	resolution	NOUN
dti-1334	106	18	)	)	PUNCT
dti-1334	106	19	is	be	AUX
dti-1334	106	20	far	far	ADV
dti-1334	106	21	smaller	small	ADJ
dti-1334	106	22	than	than	ADP
dti-1334	106	23	what	what	PRON
dti-1334	106	24	is	be	AUX
dti-1334	106	25	typically	typically	ADV
dti-1334	106	26	achieved	achieve	VERB
dti-1334	106	27	with	with	ADP
dti-1334	106	28	2	2	NUM
dti-1334	106	29	-	-	PUNCT
dti-1334	106	30	d	d	NOUN
dti-1334	106	31	page	page	NOUN
dti-1334	106	32	technology	technology	NOUN
dti-1334	106	33	(	(	PUNCT
dti-1334	106	34	somiari	somiari	PROPN
dti-1334	106	35	et	et	PROPN
dti-1334	106	36	al	al	PROPN
dti-1334	106	37	.	.	PROPN
dti-1334	106	38	2005	2005	NUM
dti-1334	106	39	)	)	PUNCT
dti-1334	106	40	,	,	PUNCT
dti-1334	106	41	although	although	SCONJ
dti-1334	106	42	this	this	PRON
dti-1334	106	43	has	have	AUX
dti-1334	106	44	been	be	AUX
dti-1334	106	45	partially	partially	ADV
dti-1334	106	46	improved	improve	VERB
dti-1334	106	47	with	with	ADP
dti-1334	106	48	technological	technological	ADJ
dti-1334	106	49	developments	development	NOUN
dti-1334	106	50	and	and	CCONJ
dti-1334	106	51	introduction	introduction	NOUN
dti-1334	106	52	of	of	ADP
dti-1334	106	53	more	more	ADJ
dti-1334	106	54	powerful	powerful	ADJ
dti-1334	106	55	softwares	software	NOUN
dti-1334	106	56	(	(	PUNCT
dti-1334	106	57	bouyssie	bouyssie	NOUN
dti-1334	106	58	et	et	PROPN
dti-1334	106	59	al	al	PROPN
dti-1334	106	60	.	.	PROPN
dti-1334	106	61	2007	2007	NUM
dti-1334	106	62	)	)	PUNCT
dti-1334	106	63	.	.	PUNCT
dti-1334	107	1	4	4	X
dti-1334	107	2	)	)	PUNCT
dti-1334	107	3	the	the	DET
dti-1334	107	4	cysteine	cysteine	NOUN
dti-1334	107	5	-	-	PUNCT
dti-1334	107	6	based	base	VERB
dti-1334	107	7	icat	icat	NOUN
dti-1334	107	8	tags	tag	NOUN
dti-1334	107	9	will	will	AUX
dti-1334	107	10	generally	generally	ADV
dti-1334	107	11	not	not	PART
dti-1334	107	12	yield	yield	VERB
dti-1334	107	13	information	information	NOUN
dti-1334	107	14	on	on	ADP
dti-1334	107	15	changes	change	NOUN
dti-1334	107	16	in	in	ADP
dti-1334	107	17	the	the	DET
dti-1334	107	18	proteome	proteome	NOUN
dti-1334	107	19	based	base	VERB
dti-1334	107	20	on	on	ADP
dti-1334	107	21	post	post	ADJ
dti-1334	107	22	-	-	ADJ
dti-1334	107	23	translational	translational	ADJ
dti-1334	107	24	modifi	modifi	NOUN
dti-1334	107	25	cations	cation	NOUN
dti-1334	107	26	.	.	PUNCT
dti-1334	108	1	5	5	X
dti-1334	108	2	)	)	PUNCT
dti-1334	108	3	avidin	avidin	NOUN
dti-1334	108	4	columns	column	NOUN
dti-1334	108	5	used	use	VERB
dti-1334	108	6	to	to	PART
dti-1334	108	7	concentrate	concentrate	VERB
dti-1334	108	8	labeled	label	VERB
dti-1334	108	9	peptides	peptide	NOUN
dti-1334	108	10	may	may	AUX
dti-1334	108	11	further	far	ADV
dti-1334	108	12	complicate	complicate	VERB
dti-1334	108	13	the	the	DET
dti-1334	108	14	analysis	analysis	NOUN
dti-1334	108	15	due	due	ADJ
dti-1334	108	16	to	to	ADP
dti-1334	108	17	non	non	ADJ
dti-1334	108	18	-	-	ADJ
dti-1334	108	19	specifi	specifi	ADJ
dti-1334	108	20	c	c	PROPN
dti-1334	108	21	binding	bind	VERB
dti-1334	108	22	and/or	and/or	CCONJ
dti-1334	108	23	irreversible	irreversible	ADJ
dti-1334	108	24	binding	binding	NOUN
dti-1334	108	25	of	of	ADP
dti-1334	108	26	the	the	DET
dti-1334	108	27	peptides	peptide	NOUN
dti-1334	108	28	(	(	PUNCT
dti-1334	108	29	moseley	moseley	NOUN
dti-1334	108	30	,	,	PUNCT
dti-1334	108	31	2001	2001	NUM
dti-1334	108	32	)	)	PUNCT
dti-1334	108	33	.	.	PUNCT
dti-1334	109	1	stable	stable	ADJ
dti-1334	109	2	isotope	isotope	NOUN
dti-1334	109	3	labeling	labeling	NOUN
dti-1334	109	4	with	with	ADP
dti-1334	109	5	amino	amino	ADJ
dti-1334	109	6	acids	acid	NOUN
dti-1334	109	7	in	in	ADP
dti-1334	109	8	cell	cell	NOUN
dti-1334	109	9	culture	culture	NOUN
dti-1334	109	10	(	(	PUNCT
dti-1334	109	11	silac	silac	PROPN
dti-1334	109	12	)	)	PUNCT
dti-1334	109	13	is	be	AUX
dti-1334	109	14	a	a	DET
dti-1334	109	15	somewhat	somewhat	ADV
dti-1334	109	16	similar	similar	ADJ
dti-1334	109	17	approach	approach	NOUN
dti-1334	109	18	which	which	PRON
dti-1334	109	19	is	be	AUX
dti-1334	109	20	used	use	VERB
dti-1334	109	21	for	for	ADP
dti-1334	109	22	incorporation	incorporation	NOUN
dti-1334	109	23	of	of	ADP
dti-1334	109	24	a	a	DET
dti-1334	109	25	label	label	NOUN
dti-1334	109	26	into	into	ADP
dti-1334	109	27	proteins	protein	NOUN
dti-1334	109	28	for	for	ADP
dti-1334	109	29	mass	mass	ADJ
dti-1334	109	30	spectrometry	spectrometry	NOUN
dti-1334	109	31	(	(	PUNCT
dti-1334	109	32	ms)-based	ms)-base	VERB
dti-1334	109	33	quantitative	quantitative	ADJ
dti-1334	109	34	proteomics	proteomic	NOUN
dti-1334	109	35	(	(	PUNCT
dti-1334	109	36	liang	liang	PROPN
dti-1334	109	37	et	et	PROPN
dti-1334	109	38	al	al	PROPN
dti-1334	109	39	.	.	PROPN
dti-1334	109	40	2006	2006	NUM
dti-1334	109	41	)	)	PUNCT
dti-1334	109	42	.	.	PUNCT
dti-1334	110	1	silac	silac	PROPN
dti-1334	110	2	relies	rely	VERB
dti-1334	110	3	on	on	ADP
dti-1334	110	4	metabolic	metabolic	NOUN
dti-1334	110	5	incorporation	incorporation	NOUN
dti-1334	110	6	of	of	ADP
dti-1334	110	7	a	a	DET
dti-1334	110	8	given	give	VERB
dti-1334	110	9	‘	'	PUNCT
dti-1334	110	10	light	light	ADJ
dti-1334	110	11	’	'	PUNCT
dti-1334	110	12	or	or	CCONJ
dti-1334	110	13	‘	'	PUNCT
dti-1334	110	14	heavy	heavy	ADJ
dti-1334	110	15	’	'	PUNCT
dti-1334	110	16	form	form	NOUN
dti-1334	110	17	of	of	ADP
dti-1334	110	18	the	the	DET
dti-1334	110	19	amino	amino	NOUN
dti-1334	110	20	acid	acid	NOUN
dti-1334	110	21	into	into	ADP
dti-1334	110	22	the	the	DET
dti-1334	110	23	proteins	protein	NOUN
dti-1334	110	24	.	.	PUNCT
dti-1334	111	1	thus	thus	ADV
dti-1334	111	2	in	in	ADP
dti-1334	111	3	an	an	DET
dti-1334	111	4	experiment	experiment	NOUN
dti-1334	111	5	,	,	PUNCT
dti-1334	111	6	two	two	NUM
dti-1334	111	7	cell	cell	NOUN
dti-1334	111	8	populations	population	NOUN
dti-1334	111	9	are	be	AUX
dti-1334	111	10	grown	grow	VERB
dti-1334	111	11	in	in	ADP
dti-1334	111	12	culture	culture	NOUN
dti-1334	111	13	media	medium	NOUN
dti-1334	111	14	that	that	PRON
dti-1334	111	15	are	be	AUX
dti-1334	111	16	identical	identical	ADJ
dti-1334	111	17	except	except	SCONJ
dti-1334	111	18	that	that	SCONJ
dti-1334	111	19	one	one	NUM
dti-1334	111	20	of	of	ADP
dti-1334	111	21	them	they	PRON
dti-1334	111	22	contains	contain	VERB
dti-1334	111	23	a	a	DET
dti-1334	111	24	‘	'	PUNCT
dti-1334	111	25	light	light	ADJ
dti-1334	111	26	’	'	PUNCT
dti-1334	111	27	and	and	CCONJ
dti-1334	111	28	the	the	DET
dti-1334	111	29	other	other	ADJ
dti-1334	111	30	a	a	DET
dti-1334	111	31	‘	'	PUNCT
dti-1334	111	32	heavy	heavy	ADJ
dti-1334	111	33	’	'	PUNCT
dti-1334	111	34	form	form	NOUN
dti-1334	111	35	of	of	ADP
dti-1334	111	36	a	a	DET
dti-1334	111	37	particular	particular	ADJ
dti-1334	111	38	amino	amino	NOUN
dti-1334	111	39	acid	acid	NOUN
dti-1334	111	40	(	(	PUNCT
dti-1334	111	41	e.g.	e.g.	ADV
dti-1334	111	42	12c	12c	NOUN
dti-1334	111	43	and	and	CCONJ
dti-1334	111	44	13c	13c	NOUN
dti-1334	111	45	labeled	label	VERB
dti-1334	111	46	l	l	NOUN
dti-1334	111	47	-	-	NOUN
dti-1334	111	48	lysine	lysine	NOUN
dti-1334	111	49	,	,	PUNCT
dti-1334	111	50	respectively	respectively	ADV
dti-1334	111	51	)	)	PUNCT
dti-1334	111	52	.	.	PUNCT
dti-1334	112	1	it	it	PRON
dti-1334	112	2	is	be	AUX
dti-1334	112	3	becoming	become	VERB
dti-1334	112	4	one	one	NUM
dti-1334	112	5	of	of	ADP
dti-1334	112	6	the	the	DET
dti-1334	112	7	highly	highly	ADV
dti-1334	112	8	effective	effective	ADJ
dti-1334	112	9	techniques	technique	NOUN
dti-1334	112	10	in	in	ADP
dti-1334	112	11	cell	cell	NOUN
dti-1334	112	12	biology	biology	NOUN
dti-1334	112	13	.	.	PUNCT
dti-1334	113	1	however	however	ADV
dti-1334	113	2	,	,	PUNCT
dti-1334	113	3	because	because	SCONJ
dti-1334	113	4	metabolic	metabolic	NOUN
dti-1334	113	5	labeling	labeling	NOUN
dti-1334	113	6	is	be	AUX
dti-1334	113	7	required	require	VERB
dti-1334	113	8	,	,	PUNCT
dti-1334	113	9	this	this	DET
dti-1334	113	10	technique	technique	NOUN
dti-1334	113	11	is	be	AUX
dti-1334	113	12	unlikely	unlikely	ADJ
dti-1334	113	13	to	to	PART
dti-1334	113	14	be	be	AUX
dti-1334	113	15	used	use	VERB
dti-1334	113	16	for	for	ADP
dti-1334	113	17	proteomic	proteomic	ADJ
dti-1334	113	18	analyses	analysis	NOUN
dti-1334	113	19	in	in	ADP
dti-1334	113	20	cancer	cancer	NOUN
dti-1334	113	21	patients	patient	NOUN
dti-1334	113	22	.	.	PUNCT
dti-1334	114	1	isobaric	isobaric	ADJ
dti-1334	114	2	tags	tag	NOUN
dti-1334	114	3	for	for	ADP
dti-1334	114	4	relative	relative	ADJ
dti-1334	114	5	and	and	CCONJ
dti-1334	114	6	absolute	absolute	ADJ
dti-1334	114	7	quantitation	quantitation	NOUN
dti-1334	114	8	(	(	PUNCT
dti-1334	114	9	itraq	itraq	PROPN
dti-1334	114	10	)	)	PUNCT
dti-1334	114	11	recently	recently	ADV
dti-1334	114	12	a	a	DET
dti-1334	114	13	new	new	ADJ
dti-1334	114	14	quantitative	quantitative	ADJ
dti-1334	114	15	method	method	NOUN
dti-1334	114	16	,	,	PUNCT
dti-1334	114	17	isobaric	isobaric	ADJ
dti-1334	114	18	tags	tag	NOUN
dti-1334	114	19	for	for	ADP
dti-1334	114	20	relative	relative	ADJ
dti-1334	114	21	and	and	CCONJ
dti-1334	114	22	absolute	absolute	ADJ
dti-1334	114	23	quantitation	quantitation	NOUN
dti-1334	114	24	(	(	PUNCT
dti-1334	114	25	itraq	itraq	PROPN
dti-1334	114	26	)	)	PUNCT
dti-1334	114	27	,	,	PUNCT
dti-1334	114	28	was	be	AUX
dti-1334	114	29	developed	develop	VERB
dti-1334	114	30	(	(	PUNCT
dti-1334	114	31	chen	chen	PROPN
dti-1334	114	32	et	et	PROPN
dti-1334	114	33	al	al	PROPN
dti-1334	114	34	.	.	PROPN
dti-1334	114	35	2007	2007	NUM
dti-1334	114	36	;	;	PUNCT
dti-1334	114	37	overall	overall	ADJ
dti-1334	114	38	and	and	CCONJ
dti-1334	114	39	dean	dean	ADJ
dti-1334	114	40	,	,	PUNCT
dti-1334	114	41	2006	2006	NUM
dti-1334	114	42	;	;	PUNCT
dti-1334	114	43	ross	ross	PROPN
dti-1334	114	44	et	et	PROPN
dti-1334	114	45	al	al	PROPN
dti-1334	114	46	.	.	PROPN
dti-1334	114	47	2004	2004	NUM
dti-1334	114	48	)	)	PUNCT
dti-1334	114	49	.	.	PUNCT
dti-1334	115	1	this	this	DET
dti-1334	115	2	technology	technology	NOUN
dti-1334	115	3	employs	employ	VERB
dti-1334	115	4	amine	amine	ADJ
dti-1334	115	5	-	-	PUNCT
dti-1334	115	6	reactive	reactive	ADJ
dti-1334	115	7	isobaric	isobaric	ADJ
dti-1334	115	8	tags	tag	NOUN
dti-1334	115	9	to	to	PART
dti-1334	115	10	label	label	NOUN
dti-1334	115	11	peptides	peptide	NOUN
dti-1334	115	12	at	at	ADP
dti-1334	115	13	the	the	DET
dti-1334	115	14	n	n	CCONJ
dti-1334	115	15	-	-	PUNCT
dti-1334	115	16	terminus	terminus	NOUN
dti-1334	115	17	and	and	CCONJ
dti-1334	115	18	the	the	DET
dti-1334	115	19	lysine	lysine	NOUN
dti-1334	115	20	side	side	NOUN
dti-1334	115	21	chains	chain	NOUN
dti-1334	115	22	,	,	PUNCT
dti-1334	115	23	thereby	thereby	ADV
dti-1334	115	24	labeling	label	VERB
dti-1334	115	25	all	all	DET
dti-1334	115	26	peptides	peptide	NOUN
dti-1334	115	27	in	in	ADP
dti-1334	115	28	a	a	DET
dti-1334	115	29	digest	digest	ADJ
dti-1334	115	30	mixture	mixture	NOUN
dti-1334	115	31	.	.	PUNCT
dti-1334	116	1	currently	currently	ADV
dti-1334	116	2	,	,	PUNCT
dti-1334	116	3	eight	eight	NUM
dti-1334	116	4	isobaric	isobaric	ADJ
dti-1334	116	5	tags	tag	NOUN
dti-1334	116	6	are	be	AUX
dti-1334	116	7	available	available	ADJ
dti-1334	116	8	,	,	PUNCT
dti-1334	116	9	allowing	allow	VERB
dti-1334	116	10	for	for	ADP
dti-1334	116	11	the	the	DET
dti-1334	116	12	labeling	labeling	NOUN
dti-1334	116	13	and	and	CCONJ
dti-1334	116	14	simultaneous	simultaneous	ADJ
dti-1334	116	15	comparison	comparison	NOUN
dti-1334	116	16	of	of	ADP
dti-1334	116	17	8	8	NUM
dti-1334	116	18	protein	protein	NOUN
dti-1334	116	19	samples	sample	NOUN
dti-1334	116	20	by	by	ADP
dti-1334	116	21	mass	mass	ADJ
dti-1334	116	22	spectrometry	spectrometry	NOUN
dti-1334	116	23	.	.	PUNCT
dti-1334	117	1	the	the	DET
dti-1334	117	2	itraq	itraq	ADV
dti-1334	117	3	-	-	PUNCT
dti-1334	117	4	based	base	VERB
dti-1334	117	5	protocol	protocol	NOUN
dti-1334	117	6	contains	contain	VERB
dti-1334	117	7	four	four	NUM
dti-1334	117	8	steps	step	NOUN
dti-1334	117	9	(	(	PUNCT
dti-1334	117	10	aggarwal	aggarwal	NOUN
dti-1334	117	11	et	et	NOUN
dti-1334	117	12	al	al	PROPN
dti-1334	117	13	.	.	PROPN
dti-1334	117	14	2006	2006	NUM
dti-1334	117	15	;	;	PUNCT
dti-1334	117	16	zieske	zieske	PROPN
dti-1334	117	17	,	,	PUNCT
dti-1334	117	18	2006	2006	NUM
dti-1334	117	19	)	)	PUNCT
dti-1334	117	20	,	,	PUNCT
dti-1334	117	21	as	as	SCONJ
dti-1334	117	22	shown	show	VERB
dti-1334	117	23	in	in	ADP
dti-1334	117	24	figure	figure	NOUN
dti-1334	117	25	1	1	NUM
dti-1334	117	26	.	.	PUNCT
dti-1334	118	1	first	first	ADV
dti-1334	118	2	,	,	PUNCT
dti-1334	118	3	protein	protein	NOUN
dti-1334	118	4	extracts	extract	NOUN
dti-1334	118	5	are	be	AUX
dti-1334	118	6	prepared	prepare	VERB
dti-1334	118	7	from	from	ADP
dti-1334	118	8	each	each	DET
dti-1334	118	9	sample	sample	NOUN
dti-1334	118	10	to	to	PART
dti-1334	118	11	be	be	AUX
dti-1334	118	12	analyzed	analyze	VERB
dti-1334	118	13	.	.	PUNCT
dti-1334	119	1	second	second	ADJ
dti-1334	119	2	,	,	PUNCT
dti-1334	119	3	proteins	protein	NOUN
dti-1334	119	4	are	be	AUX
dti-1334	119	5	separately	separately	ADV
dti-1334	119	6	digested	digest	VERB
dti-1334	119	7	into	into	ADP
dti-1334	119	8	polypeptides	polypeptide	NOUN
dti-1334	119	9	.	.	PUNCT
dti-1334	120	1	third	third	ADV
dti-1334	120	2	,	,	PUNCT
dti-1334	120	3	each	each	DET
dti-1334	120	4	set	set	NOUN
dti-1334	120	5	of	of	ADP
dti-1334	120	6	the	the	DET
dti-1334	120	7	polypeptides	polypeptide	NOUN
dti-1334	120	8	are	be	AUX
dti-1334	120	9	labeled	label	VERB
dti-1334	120	10	with	with	ADP
dti-1334	120	11	itraq	itraq	ADJ
dti-1334	120	12	reagent	reagent	NOUN
dti-1334	120	13	individually	individually	ADV
dti-1334	120	14	.	.	PUNCT
dti-1334	121	1	finally	finally	ADV
dti-1334	121	2	,	,	PUNCT
dti-1334	121	3	labeled	label	VERB
dti-1334	121	4	peptide	peptide	NOUN
dti-1334	121	5	samples	sample	NOUN
dti-1334	121	6	are	be	AUX
dti-1334	121	7	mixed	mixed	ADJ
dti-1334	121	8	and	and	CCONJ
dti-1334	121	9	the	the	DET
dti-1334	121	10	mixture	mixture	NOUN
dti-1334	121	11	is	be	AUX
dti-1334	121	12	analyzed	analyze	VERB
dti-1334	121	13	by	by	ADP
dti-1334	121	14	tandem	tandem	PROPN
dti-1334	121	15	mass	mass	PROPN
dti-1334	121	16	spectrometry	spectrometry	NOUN
dti-1334	121	17	(	(	PUNCT
dti-1334	121	18	ms	ms	PROPN
dti-1334	121	19	/	/	SYM
dti-1334	121	20	ms	ms	NOUN
dti-1334	121	21	)	)	PUNCT
dti-1334	121	22	to	to	PART
dti-1334	121	23	obtain	obtain	VERB
dti-1334	121	24	an	an	DET
dti-1334	121	25	ms	ms	PROPN
dti-1334	121	26	/	/	SYM
dti-1334	121	27	ms	ms	PROPN
dti-1334	121	28	spectrum	spectrum	NOUN
dti-1334	121	29	.	.	PUNCT
dti-1334	122	1	due	due	ADP
dti-1334	122	2	to	to	ADP
dti-1334	122	3	the	the	DET
dti-1334	122	4	large	large	ADJ
dti-1334	122	5	number	number	NOUN
dti-1334	122	6	of	of	ADP
dti-1334	122	7	peptides	peptide	NOUN
dti-1334	122	8	produced	produce	VERB
dti-1334	122	9	,	,	PUNCT
dti-1334	122	10	chromatographic	chromatographic	ADJ
dti-1334	122	11	methods	method	NOUN
dti-1334	122	12	are	be	AUX
dti-1334	122	13	often	often	ADV
dti-1334	122	14	used	use	VERB
dti-1334	122	15	individually	individually	ADV
dti-1334	122	16	or	or	CCONJ
dti-1334	122	17	in	in	ADP
dti-1334	122	18	combination	combination	NOUN
dti-1334	122	19	to	to	PART
dti-1334	122	20	fractionate	fractionate	VERB
dti-1334	122	21	the	the	DET
dti-1334	122	22	peptide	peptide	NOUN
dti-1334	122	23	mixture	mixture	NOUN
dti-1334	122	24	prior	prior	ADV
dti-1334	122	25	to	to	ADP
dti-1334	122	26	lc	lc	NOUN
dti-1334	122	27	-	-	PUNCT
dti-1334	122	28	maldi	maldi	NOUN
dti-1334	122	29	tof	tof	PROPN
dti-1334	122	30	/	/	SYM
dti-1334	122	31	tof	tof	PRON
dti-1334	122	32	or	or	CCONJ
dti-1334	122	33	lc	lc	NOUN
dti-1334	122	34	-	-	PUNCT
dti-1334	122	35	esi	esi	PROPN
dti-1334	122	36	tof	tof	PROPN
dti-1334	122	37	/	/	SYM
dti-1334	122	38	tof	tof	PROPN
dti-1334	122	39	.	.	PUNCT
dti-1334	123	1	each	each	PRON
dti-1334	123	2	of	of	ADP
dti-1334	123	3	the	the	DET
dti-1334	123	4	four	four	NUM
dti-1334	123	5	isobaric	isobaric	ADJ
dti-1334	123	6	reagents	reagent	NOUN
dti-1334	123	7	has	have	VERB
dti-1334	123	8	a	a	DET
dti-1334	123	9	mass	mass	NOUN
dti-1334	123	10	of	of	ADP
dti-1334	123	11	145	145	NUM
dti-1334	123	12	daltons	dalton	NOUN
dti-1334	123	13	,	,	PUNCT
dti-1334	123	14	and	and	CCONJ
dti-1334	123	15	consists	consist	VERB
dti-1334	123	16	of	of	ADP
dti-1334	123	17	three	three	NUM
dti-1334	123	18	groups	group	NOUN
dti-1334	123	19	:	:	PUNCT
dti-1334	123	20	reporter	reporter	NOUN
dti-1334	123	21	,	,	PUNCT
dti-1334	123	22	balance	balance	NOUN
dti-1334	123	23	,	,	PUNCT
dti-1334	123	24	and	and	CCONJ
dti-1334	123	25	reactive	reactive	ADJ
dti-1334	123	26	groups	group	NOUN
dti-1334	123	27	(	(	PUNCT
dti-1334	123	28	ross	ross	PROPN
dti-1334	123	29	et	et	PROPN
dti-1334	123	30	al	al	PROPN
dti-1334	123	31	.	.	PROPN
dti-1334	123	32	2004	2004	NUM
dti-1334	123	33	)	)	PUNCT
dti-1334	123	34	.	.	PUNCT
dti-1334	124	1	the	the	DET
dti-1334	124	2	reporter	reporter	NOUN
dti-1334	124	3	groups	group	NOUN
dti-1334	124	4	have	have	VERB
dti-1334	124	5	molecular	molecular	ADJ
dti-1334	124	6	weights	weight	NOUN
dti-1334	124	7	of	of	ADP
dti-1334	124	8	114	114	NUM
dti-1334	124	9	,	,	PUNCT
dti-1334	124	10	115	115	NUM
dti-1334	124	11	,	,	PUNCT
dti-1334	124	12	116	116	NUM
dti-1334	124	13	,	,	PUNCT
dti-1334	124	14	and	and	CCONJ
dti-1334	124	15	117	117	NUM
dti-1334	124	16	daltons	dalton	NOUN
dti-1334	124	17	,	,	PUNCT
dti-1334	124	18	respectively	respectively	ADV
dti-1334	124	19	.	.	PUNCT
dti-1334	125	1	the	the	DET
dti-1334	125	2	carbonyl	carbonyl	NOUN
dti-1334	125	3	balance	balance	NOUN
dti-1334	125	4	groups	group	NOUN
dti-1334	125	5	ensure	ensure	VERB
dti-1334	125	6	that	that	SCONJ
dti-1334	125	7	all	all	DET
dti-1334	125	8	the	the	DET
dti-1334	125	9	itraqlabeled	itraqlabele	VERB
dti-1334	125	10	peptides	peptide	NOUN
dti-1334	125	11	have	have	VERB
dti-1334	125	12	the	the	DET
dti-1334	125	13	same	same	ADJ
dti-1334	125	14	mass	mass	NOUN
dti-1334	125	15	.	.	PUNCT
dti-1334	126	1	the	the	DET
dti-1334	126	2	reactive	reactive	ADJ
dti-1334	126	3	groups	group	NOUN
dti-1334	126	4	are	be	AUX
dti-1334	126	5	attached	attach	VERB
dti-1334	126	6	to	to	ADP
dti-1334	126	7	the	the	DET
dti-1334	126	8	n	n	CCONJ
dti-1334	126	9	-	-	PUNCT
dti-1334	126	10	terminal	terminal	NOUN
dti-1334	126	11	and	and	CCONJ
dti-1334	126	12	the	the	DET
dti-1334	126	13	lysine	lysine	NOUN
dti-1334	126	14	residues	residue	NOUN
dti-1334	126	15	of	of	ADP
dti-1334	126	16	sample	sample	NOUN
dti-1334	126	17	proteins	protein	NOUN
dti-1334	126	18	.	.	PUNCT
dti-1334	127	1	in	in	ADP
dti-1334	127	2	single	single	ADJ
dti-1334	127	3	ms	ms	PROPN
dti-1334	127	4	,	,	PUNCT
dti-1334	127	5	peptides	peptide	NOUN
dti-1334	127	6	labeled	label	VERB
dti-1334	127	7	with	with	ADP
dti-1334	127	8	any	any	PRON
dti-1334	127	9	of	of	ADP
dti-1334	127	10	the	the	DET
dti-1334	127	11	isotopic	isotopic	ADJ
dti-1334	127	12	tags	tag	NOUN
dti-1334	127	13	are	be	AUX
dti-1334	127	14	indistinguishable	indistinguishable	ADJ
dti-1334	127	15	(	(	PUNCT
dti-1334	127	16	isobaric	isobaric	NOUN
dti-1334	127	17	)	)	PUNCT
dti-1334	127	18	.	.	PUNCT
dti-1334	128	1	upon	upon	SCONJ
dti-1334	128	2	fragmentation	fragmentation	NOUN
dti-1334	128	3	in	in	ADP
dti-1334	128	4	ms/	ms/	PROPN
dti-1334	128	5	ms	ms	NOUN
dti-1334	128	6	,	,	PUNCT
dti-1334	128	7	however	however	ADV
dti-1334	128	8	,	,	PUNCT
dti-1334	128	9	the	the	DET
dti-1334	128	10	reporter	reporter	NOUN
dti-1334	128	11	groups	group	NOUN
dti-1334	128	12	of	of	ADP
dti-1334	128	13	the	the	DET
dti-1334	128	14	itraq	itraq	ADJ
dti-1334	128	15	reagents	reagent	NOUN
dti-1334	128	16	will	will	AUX
dti-1334	128	17	split	split	VERB
dti-1334	128	18	from	from	ADP
dti-1334	128	19	the	the	DET
dti-1334	128	20	peptide	peptide	NOUN
dti-1334	128	21	and	and	CCONJ
dti-1334	128	22	form	form	VERB
dti-1334	128	23	small	small	ADJ
dti-1334	128	24	fragments	fragment	NOUN
dti-1334	128	25	with	with	ADP
dti-1334	128	26	mass	mass	ADJ
dti-1334	128	27	/	/	SYM
dti-1334	128	28	charges	charge	NOUN
dti-1334	128	29	(	(	PUNCT
dti-1334	128	30	m	m	NOUN
dti-1334	128	31	/	/	SYM
dti-1334	128	32	z	z	NOUN
dti-1334	128	33	)	)	PUNCT
dti-1334	128	34	of	of	ADP
dti-1334	128	35	either	either	DET
dti-1334	128	36	114	114	NUM
dti-1334	128	37	,	,	PUNCT
dti-1334	128	38	115	115	NUM
dti-1334	128	39	,	,	PUNCT
dti-1334	128	40	116	116	NUM
dti-1334	128	41	,	,	PUNCT
dti-1334	128	42	and	and	CCONJ
dti-1334	128	43	117	117	NUM
dti-1334	128	44	(	(	PUNCT
dti-1334	128	45	4	4	NUM
dti-1334	128	46	-	-	PUNCT
dti-1334	128	47	plex	plex	NOUN
dti-1334	128	48	)	)	PUNCT
dti-1334	128	49	or	or	CCONJ
dti-1334	128	50	113	113	NUM
dti-1334	128	51	,	,	PUNCT
dti-1334	128	52	114	114	NUM
dti-1334	128	53	,	,	PUNCT
dti-1334	128	54	115	115	NUM
dti-1334	128	55	,	,	PUNCT
dti-1334	128	56	116	116	NUM
dti-1334	128	57	,	,	PUNCT
dti-1334	128	58	117	117	NUM
dti-1334	128	59	,	,	PUNCT
dti-1334	128	60	118	118	NUM
dti-1334	128	61	,	,	PUNCT
dti-1334	128	62	119	119	NUM
dti-1334	128	63	,	,	PUNCT
dti-1334	128	64	and	and	CCONJ
dti-1334	128	65	121	121	NUM
dti-1334	128	66	(	(	PUNCT
dti-1334	128	67	8	8	NUM
dti-1334	128	68	-	-	PUNCT
dti-1334	128	69	plex	plex	NOUN
dti-1334	128	70	)	)	PUNCT
dti-1334	128	71	,	,	PUNCT
dti-1334	128	72	respectively	respectively	ADV
dti-1334	128	73	.	.	PUNCT
dti-1334	129	1	intensity	intensity	NOUN
dti-1334	129	2	of	of	ADP
dti-1334	129	3	each	each	PRON
dti-1334	129	4	of	of	ADP
dti-1334	129	5	these	these	DET
dti-1334	129	6	peaks	peak	NOUN
dti-1334	129	7	represents	represent	VERB
dti-1334	129	8	quantity	quantity	NOUN
dti-1334	129	9	of	of	ADP
dti-1334	129	10	small	small	ADJ
dti-1334	129	11	reporter	reporter	NOUN
dti-1334	129	12	group	group	NOUN
dti-1334	129	13	fragment	fragment	NOUN
dti-1334	129	14	and	and	CCONJ
dti-1334	129	15	thus	thus	ADV
dti-1334	129	16	represents	represent	VERB
dti-1334	129	17	the	the	DET
dti-1334	129	18	quantity	quantity	NOUN
dti-1334	129	19	of	of	ADP
dti-1334	129	20	a	a	DET
dti-1334	129	21	peptide	peptide	NOUN
dti-1334	129	22	.	.	PUNCT
dti-1334	130	1	ms	ms	PROPN
dti-1334	130	2	/	/	SYM
dti-1334	130	3	ms	ms	PROPN
dti-1334	130	4	analysis	analysis	NOUN
dti-1334	130	5	will	will	AUX
dti-1334	130	6	also	also	ADV
dti-1334	130	7	generate	generate	VERB
dti-1334	130	8	peaks	peak	NOUN
dti-1334	130	9	from	from	ADP
dti-1334	130	10	polypeptides	polypeptide	NOUN
dti-1334	130	11	which	which	PRON
dti-1334	130	12	allow	allow	VERB
dti-1334	130	13	the	the	DET
dti-1334	130	14	identifi	identifi	PROPN
dti-1334	130	15	cation	cation	NOUN
dti-1334	130	16	of	of	ADP
dti-1334	130	17	peptide	peptide	ADJ
dti-1334	130	18	sequences	sequence	NOUN
dti-1334	130	19	and	and	CCONJ
dti-1334	130	20	therefore	therefore	ADV
dti-1334	130	21	protein	protein	NOUN
dti-1334	130	22	sequences	sequence	NOUN
dti-1334	130	23	.	.	PUNCT
dti-1334	131	1	the	the	DET
dti-1334	131	2	advantages	advantage	NOUN
dti-1334	131	3	of	of	ADP
dti-1334	131	4	itraq	itraq	ADJ
dti-1334	131	5	include	include	NOUN
dti-1334	131	6	:	:	PUNCT
dti-1334	131	7	1	1	X
dti-1334	131	8	)	)	PUNCT
dti-1334	131	9	all	all	DET
dti-1334	131	10	tryptic	tryptic	ADJ
dti-1334	131	11	peptides	peptide	NOUN
dti-1334	131	12	are	be	AUX
dti-1334	131	13	labeled	label	VERB
dti-1334	131	14	resulting	result	VERB
dti-1334	131	15	in	in	ADP
dti-1334	131	16	increased	increase	VERB
dti-1334	131	17	confi	confi	NOUN
dti-1334	131	18	dence	dence	NOUN
dti-1334	131	19	and	and	CCONJ
dti-1334	131	20	higher	high	ADJ
dti-1334	131	21	quality	quality	NOUN
dti-1334	131	22	data	datum	NOUN
dti-1334	131	23	;	;	PUNCT
dti-1334	131	24	2	2	X
dti-1334	131	25	)	)	PUNCT
dti-1334	131	26	up	up	ADP
dti-1334	131	27	to	to	PART
dti-1334	131	28	8	8	NUM
dti-1334	131	29	labels	label	NOUN
dti-1334	131	30	can	can	AUX
dti-1334	131	31	be	be	AUX
dti-1334	131	32	used	use	VERB
dti-1334	131	33	for	for	ADP
dti-1334	131	34	multiplexing	multiplexe	VERB
dti-1334	131	35	experiments	experiment	NOUN
dti-1334	131	36	;	;	PUNCT
dti-1334	131	37	3	3	X
dti-1334	131	38	)	)	PUNCT
dti-1334	131	39	improved	improve	VERB
dti-1334	131	40	ms	ms	PROPN
dti-1334	131	41	/	/	SYM
dti-1334	131	42	ms	ms	PROPN
dti-1334	131	43	fragmentation	fragmentation	NOUN
dti-1334	131	44	results	result	NOUN
dti-1334	131	45	in	in	ADP
dti-1334	131	46	more	more	ADJ
dti-1334	131	47	confi	confi	ADJ
dti-1334	131	48	dent	dent	NOUN
dti-1334	131	49	peptide	peptide	NOUN
dti-1334	131	50	or	or	CCONJ
dti-1334	131	51	protein	protein	NOUN
dti-1334	131	52	identifi	identifi	NOUN
dti-1334	131	53	cations	cation	NOUN
dti-1334	131	54	;	;	PUNCT
dti-1334	131	55	and	and	CCONJ
dti-1334	131	56	4	4	X
dti-1334	131	57	)	)	PUNCT
dti-1334	131	58	post	post	VERB
dti-1334	131	59	translational	translational	ADJ
dti-1334	131	60	modifi	modifi	NOUN
dti-1334	131	61	cations	cation	NOUN
dti-1334	131	62	,	,	PUNCT
dti-1334	131	63	such	such	ADJ
dti-1334	131	64	as	as	ADP
dti-1334	131	65	phosphorylation	phosphorylation	NOUN
dti-1334	131	66	,	,	PUNCT
dti-1334	131	67	can	can	AUX
dti-1334	131	68	be	be	AUX
dti-1334	131	69	analyzed	analyze	VERB
dti-1334	131	70	(	(	PUNCT
dti-1334	131	71	gafken	gafken	VERB
dti-1334	131	72	and	and	CCONJ
dti-1334	131	73	lampe	lampe	NOUN
dti-1334	131	74	,	,	PUNCT
dti-1334	131	75	2006	2006	NUM
dti-1334	131	76	)	)	PUNCT
dti-1334	131	77	.	.	PUNCT
dti-1334	132	1	the	the	DET
dti-1334	132	2	key	key	ADJ
dti-1334	132	3	60	60	NUM
dti-1334	132	4	shen	shen	NOUN
dti-1334	132	5	et	et	PROPN
dti-1334	132	6	al	al	PROPN
dti-1334	132	7	drug	drug	PROPN
dti-1334	132	8	target	target	NOUN
dti-1334	132	9	insights	insight	NOUN
dti-1334	132	10	2008:3	2008:3	NUM
dti-1334	132	11	disadvantages	disadvantage	NOUN
dti-1334	132	12	of	of	ADP
dti-1334	132	13	itraq	itraq	ADJ
dti-1334	132	14	include	include	NOUN
dti-1334	132	15	:	:	PUNCT
dti-1334	132	16	1	1	X
dti-1334	132	17	)	)	PUNCT
dti-1334	132	18	more	more	ADJ
dti-1334	132	19	mass	mass	ADJ
dti-1334	132	20	spectrometry	spectrometry	NOUN
dti-1334	132	21	time	time	NOUN
dti-1334	132	22	is	be	AUX
dti-1334	132	23	required	require	VERB
dti-1334	132	24	because	because	SCONJ
dti-1334	132	25	of	of	ADP
dti-1334	132	26	the	the	DET
dti-1334	132	27	increased	increase	VERB
dti-1334	132	28	number	number	NOUN
dti-1334	132	29	of	of	ADP
dti-1334	132	30	peptides	peptide	NOUN
dti-1334	132	31	;	;	PUNCT
dti-1334	132	32	and	and	CCONJ
dti-1334	132	33	2	2	X
dti-1334	132	34	)	)	PUNCT
dti-1334	132	35	samples	sample	NOUN
dti-1334	132	36	must	must	AUX
dti-1334	132	37	be	be	AUX
dti-1334	132	38	prepared	prepare	VERB
dti-1334	132	39	according	accord	VERB
dti-1334	132	40	to	to	ADP
dti-1334	132	41	very	very	ADV
dti-1334	132	42	strict	strict	ADJ
dti-1334	132	43	guidelines	guideline	NOUN
dti-1334	132	44	(	(	PUNCT
dti-1334	132	45	aggarwal	aggarwal	NOUN
dti-1334	132	46	et	et	NOUN
dti-1334	132	47	al	al	PROPN
dti-1334	132	48	.	.	PROPN
dti-1334	132	49	2006	2006	NUM
dti-1334	132	50	)	)	PUNCT
dti-1334	132	51	.	.	PUNCT
dti-1334	133	1	surface	surface	NOUN
dti-1334	133	2	enhanced	enhance	VERB
dti-1334	133	3	laser	laser	NOUN
dti-1334	133	4	desorption	desorption	NOUN
dti-1334	133	5	ionization	ionization	NOUN
dti-1334	133	6	-	-	PUNCT
dti-1334	133	7	time	time	NOUN
dti-1334	133	8	of	of	ADP
dti-1334	133	9	fl	fl	NUM
dti-1334	133	10	ight	ight	ADJ
dti-1334	133	11	(	(	PUNCT
dti-1334	133	12	seldi	seldi	PROPN
dti-1334	133	13	-	-	PUNCT
dti-1334	133	14	tof	tof	PROPN
dti-1334	133	15	)	)	PUNCT
dti-1334	133	16	surface	surface	NOUN
dti-1334	133	17	enhanced	enhance	VERB
dti-1334	133	18	laser	laser	NOUN
dti-1334	133	19	desorption	desorption	NOUN
dti-1334	133	20	ionization	ionization	NOUN
dti-1334	133	21	-	-	PUNCT
dti-1334	133	22	time	time	NOUN
dti-1334	133	23	of	of	ADP
dti-1334	133	24	fl	fl	NUM
dti-1334	133	25	ight	ight	ADJ
dti-1334	133	26	(	(	PUNCT
dti-1334	133	27	seldi	seldi	PROPN
dti-1334	133	28	-	-	PUNCT
dti-1334	133	29	tof	tof	PROPN
dti-1334	133	30	)	)	PUNCT
dti-1334	133	31	is	be	AUX
dti-1334	133	32	a	a	DET
dti-1334	133	33	relatively	relatively	ADV
dti-1334	133	34	novel	novel	ADJ
dti-1334	133	35	and	and	CCONJ
dti-1334	133	36	straightforward	straightforward	ADJ
dti-1334	133	37	proteomic	proteomic	ADJ
dti-1334	133	38	technology	technology	NOUN
dti-1334	133	39	that	that	PRON
dti-1334	133	40	can	can	AUX
dti-1334	133	41	be	be	AUX
dti-1334	133	42	used	use	VERB
dti-1334	133	43	for	for	ADP
dti-1334	133	44	quantitative	quantitative	ADJ
dti-1334	133	45	analysis	analysis	NOUN
dti-1334	133	46	of	of	ADP
dti-1334	133	47	protein	protein	NOUN
dti-1334	133	48	mixtures	mixture	NOUN
dti-1334	133	49	after	after	ADP
dti-1334	133	50	selectively	selectively	ADV
dti-1334	133	51	capturing	capture	VERB
dti-1334	133	52	proteins	protein	NOUN
dti-1334	133	53	with	with	ADP
dti-1334	133	54	unique	unique	ADJ
dti-1334	133	55	attributes	attribute	NOUN
dti-1334	133	56	on	on	ADP
dti-1334	133	57	activated	activated	ADJ
dti-1334	133	58	surfaces	surface	NOUN
dti-1334	133	59	(	(	PUNCT
dti-1334	133	60	maurya	maurya	PROPN
dti-1334	133	61	et	et	PROPN
dti-1334	133	62	al	al	PROPN
dti-1334	133	63	.	.	PROPN
dti-1334	133	64	2007	2007	NUM
dti-1334	133	65	;	;	PUNCT
dti-1334	133	66	poon	poon	NOUN
dti-1334	133	67	,	,	PUNCT
dti-1334	133	68	2007	2007	NUM
dti-1334	133	69	)	)	PUNCT
dti-1334	133	70	.	.	PUNCT
dti-1334	134	1	this	this	DET
dti-1334	134	2	technique	technique	NOUN
dti-1334	134	3	utilizes	utilize	VERB
dti-1334	134	4	stainless	stainless	ADJ
dti-1334	134	5	steel	steel	NOUN
dti-1334	134	6	or	or	CCONJ
dti-1334	134	7	aluminum	aluminum	NOUN
dti-1334	134	8	-	-	PUNCT
dti-1334	134	9	based	base	VERB
dti-1334	134	10	supports	support	NOUN
dti-1334	134	11	,	,	PUNCT
dti-1334	134	12	or	or	CCONJ
dti-1334	134	13	chips	chip	NOUN
dti-1334	134	14	,	,	PUNCT
dti-1334	134	15	engineered	engineer	VERB
dti-1334	134	16	with	with	ADP
dti-1334	134	17	binding	bind	VERB
dti-1334	134	18	features	feature	NOUN
dti-1334	134	19	that	that	PRON
dti-1334	134	20	have	have	VERB
dti-1334	134	21	either	either	CCONJ
dti-1334	134	22	chemical	chemical	NOUN
dti-1334	134	23	(	(	PUNCT
dti-1334	134	24	hydrophilic	hydrophilic	ADJ
dti-1334	134	25	,	,	PUNCT
dti-1334	134	26	hydrophobic	hydrophobic	NOUN
dti-1334	134	27	,	,	PUNCT
dti-1334	134	28	pre	pre	ADJ
dti-1334	134	29	-	-	VERB
dti-1334	134	30	activated	activated	ADJ
dti-1334	134	31	,	,	PUNCT
dti-1334	134	32	normal	normal	ADJ
dti-1334	134	33	-	-	PUNCT
dti-1334	134	34	phase	phase	NOUN
dti-1334	134	35	,	,	PUNCT
dti-1334	134	36	immobilized	immobilized	ADJ
dti-1334	134	37	metal	metal	NOUN
dti-1334	134	38	affi	affi	PROPN
dti-1334	134	39	nity	nity	NOUN
dti-1334	134	40	,	,	PUNCT
dti-1334	134	41	and	and	CCONJ
dti-1334	134	42	cationic	cationic	ADJ
dti-1334	134	43	or	or	CCONJ
dti-1334	134	44	anionic	anionic	ADJ
dti-1334	134	45	)	)	PUNCT
dti-1334	134	46	or	or	CCONJ
dti-1334	134	47	biological	biological	ADJ
dti-1334	134	48	(	(	PUNCT
dti-1334	134	49	antibody	antibody	NOUN
dti-1334	134	50	,	,	PUNCT
dti-1334	134	51	antigen	antigen	ADJ
dti-1334	134	52	binding	bind	VERB
dti-1334	134	53	fragments	fragment	NOUN
dti-1334	134	54	(	(	PUNCT
dti-1334	134	55	e.g.	e.g.	ADV
dti-1334	134	56	scfv	scfv	PROPN
dti-1334	134	57	)	)	PUNCT
dti-1334	134	58	,	,	PUNCT
dti-1334	134	59	dna	dna	NOUN
dti-1334	134	60	,	,	PUNCT
dti-1334	134	61	enzyme	enzyme	NOUN
dti-1334	134	62	,	,	PUNCT
dti-1334	134	63	or	or	CCONJ
dti-1334	134	64	receptor	receptor	NOUN
dti-1334	134	65	)	)	PUNCT
dti-1334	134	66	bait	bait	NOUN
dti-1334	134	67	surfaces	surface	NOUN
dti-1334	134	68	(	(	PUNCT
dti-1334	134	69	roelofsen	roelofsen	VERB
dti-1334	134	70	et	et	PROPN
dti-1334	134	71	al	al	PROPN
dti-1334	134	72	.	.	PROPN
dti-1334	134	73	2007	2007	NUM
dti-1334	134	74	;	;	PUNCT
dti-1334	134	75	szalowska	szalowska	NOUN
dti-1334	134	76	et	et	PROPN
dti-1334	134	77	al	al	PROPN
dti-1334	134	78	.	.	PROPN
dti-1334	134	79	2007	2007	NUM
dti-1334	134	80	)	)	PUNCT
dti-1334	134	81	.	.	PUNCT
dti-1334	135	1	solubilized	solubilize	VERB
dti-1334	135	2	tissue	tissue	NOUN
dti-1334	135	3	protein	protein	NOUN
dti-1334	135	4	samples	sample	NOUN
dti-1334	135	5	or	or	CCONJ
dti-1334	135	6	body	body	NOUN
dti-1334	135	7	fl	fl	PROPN
dti-1334	135	8	uids	uid	NOUN
dti-1334	135	9	are	be	AUX
dti-1334	135	10	directly	directly	ADV
dti-1334	135	11	applied	apply	VERB
dti-1334	135	12	to	to	ADP
dti-1334	135	13	the	the	DET
dti-1334	135	14	chips	chip	NOUN
dti-1334	135	15	,	,	PUNCT
dti-1334	135	16	where	where	SCONJ
dti-1334	135	17	proteins	protein	NOUN
dti-1334	135	18	can	can	AUX
dti-1334	135	19	bind	bind	VERB
dti-1334	135	20	to	to	ADP
dti-1334	135	21	different	different	ADJ
dti-1334	135	22	chromatographic	chromatographic	ADJ
dti-1334	135	23	surfaces	surface	NOUN
dti-1334	135	24	to	to	PART
dti-1334	135	25	retain	retain	VERB
dti-1334	135	26	proteins	protein	NOUN
dti-1334	135	27	with	with	ADP
dti-1334	135	28	specifi	specifi	PROPN
dti-1334	135	29	c	c	PROPN
dti-1334	135	30	features	feature	NOUN
dti-1334	135	31	.	.	PUNCT
dti-1334	136	1	after	after	ADP
dti-1334	136	2	removing	remove	VERB
dti-1334	136	3	unbound	unbound	ADJ
dti-1334	136	4	proteins	protein	NOUN
dti-1334	136	5	through	through	ADP
dti-1334	136	6	serial	serial	ADJ
dti-1334	136	7	washes	wash	NOUN
dti-1334	136	8	,	,	PUNCT
dti-1334	136	9	the	the	DET
dti-1334	136	10	bound	bind	VERB
dti-1334	136	11	proteins	protein	NOUN
dti-1334	136	12	are	be	AUX
dti-1334	136	13	subjected	subject	VERB
dti-1334	136	14	to	to	ADP
dti-1334	136	15	analysis	analysis	NOUN
dti-1334	136	16	by	by	ADP
dti-1334	136	17	laser	laser	NOUN
dti-1334	136	18	desorption	desorption	NOUN
dti-1334	136	19	ionizationtime	ionizationtime	NOUN
dti-1334	136	20	of	of	ADP
dti-1334	136	21	flight	flight	NOUN
dti-1334	136	22	mass	mass	NOUN
dti-1334	136	23	spectrometry	spectrometry	NOUN
dti-1334	136	24	.	.	PUNCT
dti-1334	137	1	masses	masse	NOUN
dti-1334	137	2	of	of	ADP
dti-1334	137	3	proteins	protein	NOUN
dti-1334	137	4	ranging	range	VERB
dti-1334	137	5	from	from	ADP
dti-1334	137	6	small	small	ADJ
dti-1334	137	7	peptides	peptide	NOUN
dti-1334	137	8	of	of	ADP
dti-1334	137	9	less	less	ADJ
dti-1334	137	10	than	than	ADP
dti-1334	137	11	1	1	NUM
dti-1334	137	12	kda	kda	NOUN
dti-1334	137	13	up	up	ADP
dti-1334	137	14	to	to	ADP
dti-1334	137	15	proteins	protein	NOUN
dti-1334	137	16	of	of	ADP
dti-1334	137	17	greater	great	ADJ
dti-1334	137	18	than	than	ADP
dti-1334	137	19	300	300	NUM
dti-1334	137	20	kda	kda	NOUN
dti-1334	137	21	are	be	AUX
dti-1334	137	22	calculated	calculate	VERB
dti-1334	137	23	based	base	VERB
dti-1334	137	24	on	on	ADP
dti-1334	137	25	time	time	NOUN
dti-1334	137	26	-	-	PUNCT
dti-1334	137	27	of	of	ADP
dti-1334	137	28	-	-	PUNCT
dti-1334	137	29	fl	fl	NOUN
dti-1334	137	30	ight	ight	NOUN
dti-1334	137	31	.	.	PUNCT
dti-1334	138	1	as	as	SCONJ
dti-1334	138	2	mixtures	mixture	NOUN
dti-1334	138	3	of	of	ADP
dti-1334	138	4	proteins	protein	NOUN
dti-1334	138	5	will	will	AUX
dti-1334	138	6	be	be	AUX
dti-1334	138	7	analyzed	analyze	VERB
dti-1334	138	8	within	within	ADP
dti-1334	138	9	different	different	ADJ
dti-1334	138	10	samples	sample	NOUN
dti-1334	138	11	,	,	PUNCT
dti-1334	138	12	a	a	DET
dti-1334	138	13	unique	unique	ADJ
dti-1334	138	14	sample	sample	NOUN
dti-1334	138	15	fi	fi	NOUN
dti-1334	138	16	ngerprint	ngerprint	NOUN
dti-1334	138	17	or	or	CCONJ
dti-1334	138	18	signature	signature	NOUN
dti-1334	138	19	will	will	AUX
dti-1334	138	20	result	result	VERB
dti-1334	138	21	for	for	SCONJ
dti-1334	138	22	each	each	DET
dti-1334	138	23	sample	sample	NOUN
dti-1334	138	24	tested	test	VERB
dti-1334	138	25	.	.	PUNCT
dti-1334	139	1	consequently	consequently	ADV
dti-1334	139	2	,	,	PUNCT
dti-1334	139	3	patterns	pattern	NOUN
dti-1334	139	4	of	of	ADP
dti-1334	139	5	masses	masse	NOUN
dti-1334	139	6	rather	rather	ADV
dti-1334	139	7	than	than	ADP
dti-1334	139	8	actual	actual	ADJ
dti-1334	139	9	protein	protein	NOUN
dti-1334	139	10	identifi	identifi	NOUN
dti-1334	139	11	cations	cation	NOUN
dti-1334	139	12	are	be	AUX
dti-1334	139	13	produced	produce	VERB
dti-1334	139	14	by	by	ADP
dti-1334	139	15	seldi	seldi	PROPN
dti-1334	139	16	analysis	analysis	NOUN
dti-1334	139	17	.	.	PUNCT
dti-1334	140	1	this	this	PRON
dti-1334	140	2	allows	allow	VERB
dti-1334	140	3	for	for	ADP
dti-1334	140	4	comparison	comparison	NOUN
dti-1334	140	5	of	of	ADP
dti-1334	140	6	spectra	spectra	NOUN
dti-1334	140	7	of	of	ADP
dti-1334	140	8	a	a	DET
dti-1334	140	9	large	large	ADJ
dti-1334	140	10	number	number	NOUN
dti-1334	140	11	of	of	ADP
dti-1334	140	12	samples	sample	NOUN
dti-1334	140	13	within	within	ADP
dti-1334	140	14	an	an	DET
dti-1334	140	15	abbreviated	abbreviate	VERB
dti-1334	140	16	time	time	NOUN
dti-1334	140	17	frame	frame	NOUN
dti-1334	140	18	and	and	CCONJ
dti-1334	140	19	acquisition	acquisition	NOUN
dti-1334	140	20	of	of	ADP
dti-1334	140	21	differentially	differentially	ADV
dti-1334	140	22	expressed	express	VERB
dti-1334	140	23	proteomic	proteomic	ADJ
dti-1334	140	24	patterns	pattern	NOUN
dti-1334	140	25	.	.	PUNCT
dti-1334	141	1	seldi	seldi	PROPN
dti-1334	141	2	-	-	PUNCT
dti-1334	141	3	tof	tof	PROPN
dti-1334	141	4	is	be	AUX
dti-1334	141	5	a	a	DET
dti-1334	141	6	potentially	potentially	ADV
dti-1334	141	7	powerful	powerful	ADJ
dti-1334	141	8	clinical	clinical	ADJ
dti-1334	141	9	proteomics	proteomic	NOUN
dti-1334	141	10	tool	tool	NOUN
dti-1334	141	11	for	for	ADP
dti-1334	141	12	identifi	identifi	PROPN
dti-1334	141	13	cation	cation	NOUN
dti-1334	141	14	of	of	ADP
dti-1334	141	15	patients	patient	NOUN
dti-1334	141	16	at	at	ADP
dti-1334	141	17	risk	risk	NOUN
dti-1334	141	18	for	for	ADP
dti-1334	141	19	development	development	NOUN
dti-1334	141	20	of	of	ADP
dti-1334	141	21	cancer	cancer	NOUN
dti-1334	141	22	based	base	VERB
dti-1334	141	23	on	on	ADP
dti-1334	141	24	the	the	DET
dti-1334	141	25	direct	direct	ADJ
dti-1334	141	26	analysis	analysis	NOUN
dti-1334	141	27	of	of	ADP
dti-1334	141	28	body	body	NOUN
dti-1334	141	29	fl	fl	PROPN
dti-1334	141	30	uids	uid	NOUN
dti-1334	141	31	like	like	ADP
dti-1334	141	32	serum	serum	NOUN
dti-1334	141	33	,	,	PUNCT
dti-1334	141	34	plasma	plasma	NOUN
dti-1334	141	35	,	,	PUNCT
dti-1334	141	36	ductal	ductal	ADJ
dti-1334	141	37	lavage	lavage	NOUN
dti-1334	141	38	,	,	PUNCT
dti-1334	141	39	cerebro	cerebro	NOUN
dti-1334	141	40	spinal	spinal	NOUN
dti-1334	141	41	fl	fl	X
dti-1334	141	42	uid	uid	ADJ
dti-1334	141	43	and	and	CCONJ
dti-1334	141	44	urine	urine	NOUN
dti-1334	141	45	(	(	PUNCT
dti-1334	141	46	maurya	maurya	PROPN
dti-1334	141	47	et	et	PROPN
dti-1334	141	48	al	al	PROPN
dti-1334	141	49	.	.	PROPN
dti-1334	141	50	2007	2007	NUM
dti-1334	141	51	;	;	PUNCT
dti-1334	141	52	poon	poon	NOUN
dti-1334	141	53	,	,	PUNCT
dti-1334	141	54	2007	2007	NUM
dti-1334	141	55	;	;	PUNCT
dti-1334	141	56	zhang	zhang	PROPN
dti-1334	141	57	et	et	PROPN
dti-1334	141	58	al	al	PROPN
dti-1334	141	59	.	.	PROPN
dti-1334	141	60	2006	2006	NUM
dti-1334	141	61	)	)	PUNCT
dti-1334	141	62	.	.	PUNCT
dti-1334	142	1	a	a	DET
dti-1334	142	2	high	high	ADJ
dti-1334	142	3	profile	profile	NOUN
dti-1334	142	4	and	and	CCONJ
dti-1334	142	5	well	well	ADV
dti-1334	142	6	publicized	publicize	VERB
dti-1334	142	7	ovarian	ovarian	ADJ
dti-1334	142	8	cancer	cancer	NOUN
dti-1334	142	9	study	study	NOUN
dti-1334	142	10	utilized	utilize	VERB
dti-1334	142	11	seldi	seldi	PROPN
dti-1334	142	12	-	-	PUNCT
dti-1334	142	13	tof	tof	PROPN
dti-1334	142	14	to	to	PART
dti-1334	142	15	identify	identify	VERB
dti-1334	142	16	protein	protein	NOUN
dti-1334	142	17	peaks	peak	NOUN
dti-1334	142	18	in	in	ADP
dti-1334	142	19	serum	serum	NOUN
dti-1334	142	20	that	that	PRON
dti-1334	142	21	distinguished	distinguish	VERB
dti-1334	142	22	patients	patient	NOUN
dti-1334	142	23	with	with	ADP
dti-1334	142	24	ovarian	ovarian	ADJ
dti-1334	142	25	cancer	cancer	NOUN
dti-1334	142	26	from	from	ADP
dti-1334	142	27	those	those	PRON
dti-1334	142	28	without	without	ADP
dti-1334	142	29	ovarian	ovarian	ADJ
dti-1334	142	30	cancer	cancer	NOUN
dti-1334	142	31	(	(	PUNCT
dti-1334	142	32	petricoin	petricoin	INTJ
dti-1334	142	33	et	et	PROPN
dti-1334	142	34	al	al	PROPN
dti-1334	142	35	.	.	PROPN
dti-1334	142	36	2002	2002	NUM
dti-1334	142	37	)	)	PUNCT
dti-1334	142	38	.	.	PUNCT
dti-1334	143	1	while	while	SCONJ
dti-1334	143	2	the	the	DET
dti-1334	143	3	study	study	NOUN
dti-1334	143	4	design	design	NOUN
dti-1334	143	5	,	,	PUNCT
dti-1334	143	6	sensitivity	sensitivity	NOUN
dti-1334	143	7	and	and	CCONJ
dti-1334	143	8	specifi	specifi	PROPN
dti-1334	143	9	city	city	PROPN
dti-1334	143	10	reported	report	VERB
dti-1334	143	11	have	have	AUX
dti-1334	143	12	generated	generate	VERB
dti-1334	143	13	counter	counter	ADJ
dti-1334	143	14	comments	comment	NOUN
dti-1334	143	15	,	,	PUNCT
dti-1334	143	16	the	the	DET
dti-1334	143	17	seldi	seldi	PROPN
dti-1334	143	18	-	-	PUNCT
dti-1334	143	19	tof	tof	PROPN
dti-1334	143	20	is	be	AUX
dti-1334	143	21	an	an	DET
dti-1334	143	22	emerging	emerge	VERB
dti-1334	143	23	and	and	CCONJ
dti-1334	143	24	potentially	potentially	ADV
dti-1334	143	25	powerful	powerful	ADJ
dti-1334	143	26	proteomic	proteomic	ADJ
dti-1334	143	27	tool	tool	NOUN
dti-1334	143	28	that	that	PRON
dti-1334	143	29	has	have	AUX
dti-1334	143	30	attributes	attribute	NOUN
dti-1334	143	31	,	,	PUNCT
dti-1334	143	32	e.g.	e.g.	ADV
dti-1334	143	33	cost	cost	NOUN
dti-1334	143	34	and	and	CCONJ
dti-1334	143	35	ease	ease	NOUN
dti-1334	143	36	of	of	ADP
dti-1334	143	37	use	use	NOUN
dti-1334	143	38	,	,	PUNCT
dti-1334	143	39	that	that	PRON
dti-1334	143	40	are	be	AUX
dti-1334	143	41	lacking	lack	VERB
dti-1334	143	42	in	in	ADP
dti-1334	143	43	other	other	ADJ
dti-1334	143	44	proteomics	proteomic	NOUN
dti-1334	143	45	technologies	technology	NOUN
dti-1334	143	46	.	.	PUNCT
dti-1334	144	1	protein	protein	NOUN
dti-1334	144	2	array	array	VERB
dti-1334	144	3	protein	protein	NOUN
dti-1334	144	4	arrays	array	NOUN
dti-1334	144	5	are	be	AUX
dti-1334	144	6	solid	solid	ADJ
dti-1334	144	7	-	-	PUNCT
dti-1334	144	8	phase	phase	NOUN
dti-1334	144	9	ligand	ligand	NOUN
dti-1334	144	10	binding	bind	VERB
dti-1334	144	11	assay	assay	NOUN
dti-1334	144	12	systems	system	NOUN
dti-1334	144	13	comprising	comprising	NOUN
dti-1334	144	14	of	of	ADP
dti-1334	144	15	immobilized	immobilized	ADJ
dti-1334	144	16	biological	biological	ADJ
dti-1334	144	17	molecules	molecule	NOUN
dti-1334	144	18	on	on	ADP
dti-1334	144	19	solid	solid	ADJ
dti-1334	144	20	surfaces	surface	NOUN
dti-1334	144	21	which	which	PRON
dti-1334	144	22	include	include	VERB
dti-1334	144	23	glass	glass	NOUN
dti-1334	144	24	,	,	PUNCT
dti-1334	144	25	membranes	membrane	NOUN
dti-1334	144	26	,	,	PUNCT
dti-1334	144	27	microtiter	microtiter	ADJ
dti-1334	144	28	wells	well	NOUN
dti-1334	144	29	,	,	PUNCT
dti-1334	144	30	mass	mass	ADJ
dti-1334	144	31	spectrometer	spectrometer	NOUN
dti-1334	144	32	plates	plate	NOUN
dti-1334	144	33	,	,	PUNCT
dti-1334	144	34	and	and	CCONJ
dti-1334	144	35	beads	bead	NOUN
dti-1334	144	36	or	or	CCONJ
dti-1334	144	37	other	other	ADJ
dti-1334	144	38	particles	particle	NOUN
dti-1334	144	39	(	(	PUNCT
dti-1334	144	40	clarke	clarke	PROPN
dti-1334	144	41	and	and	CCONJ
dti-1334	144	42	chan	chan	PROPN
dti-1334	144	43	,	,	PUNCT
dti-1334	144	44	2005	2005	NUM
dti-1334	144	45	;	;	PUNCT
dti-1334	144	46	lueking	lueke	VERB
dti-1334	144	47	et	et	PROPN
dti-1334	144	48	al	al	PROPN
dti-1334	144	49	.	.	PROPN
dti-1334	144	50	2005	2005	NUM
dti-1334	144	51	)	)	PUNCT
dti-1334	144	52	.	.	PUNCT
dti-1334	145	1	the	the	DET
dti-1334	145	2	assays	assay	NOUN
dti-1334	145	3	are	be	AUX
dti-1334	145	4	highly	highly	ADV
dti-1334	145	5	parallel	parallel	ADJ
dti-1334	145	6	(	(	PUNCT
dti-1334	145	7	multiplexed	multiplexed	ADJ
dti-1334	145	8	)	)	PUNCT
dti-1334	145	9	and	and	CCONJ
dti-1334	145	10	often	often	ADV
dti-1334	145	11	miniaturized	miniaturize	VERB
dti-1334	145	12	(	(	PUNCT
dti-1334	145	13	microarrays	microarray	NOUN
dti-1334	145	14	,	,	PUNCT
dti-1334	145	15	protein	protein	NOUN
dti-1334	145	16	chips	chip	NOUN
dti-1334	145	17	)	)	PUNCT
dti-1334	145	18	.	.	PUNCT
dti-1334	146	1	biological	biological	ADJ
dti-1334	146	2	molecules	molecule	NOUN
dti-1334	146	3	such	such	ADJ
dti-1334	146	4	as	as	ADP
dti-1334	146	5	antibodies	antibody	NOUN
dti-1334	146	6	,	,	PUNCT
dti-1334	146	7	proteins	protein	NOUN
dti-1334	146	8	,	,	PUNCT
dti-1334	146	9	protein	protein	NOUN
dti-1334	146	10	fragments	fragment	NOUN
dti-1334	146	11	,	,	PUNCT
dti-1334	146	12	peptides	peptide	NOUN
dti-1334	146	13	,	,	PUNCT
dti-1334	146	14	aptamers	aptamer	NOUN
dti-1334	146	15	or	or	CCONJ
dti-1334	146	16	carbohydrate	carbohydrate	NOUN
dti-1334	146	17	are	be	AUX
dti-1334	146	18	affi	affi	VERB
dti-1334	146	19	xed	xed	PROPN
dti-1334	146	20	in	in	ADP
dti-1334	146	21	a	a	DET
dti-1334	146	22	grid	grid	NOUN
dti-1334	146	23	-	-	PUNCT
dti-1334	146	24	like	like	ADJ
dti-1334	146	25	pattern	pattern	NOUN
dti-1334	146	26	on	on	ADP
dti-1334	146	27	small	small	ADJ
dti-1334	146	28	surfaces	surface	NOUN
dti-1334	146	29	thus	thus	ADV
dti-1334	146	30	forming	form	VERB
dti-1334	146	31	a	a	DET
dti-1334	146	32	microscopic	microscopic	ADJ
dti-1334	146	33	array	array	NOUN
dti-1334	146	34	(	(	PUNCT
dti-1334	146	35	collett	collett	PROPN
dti-1334	146	36	et	et	PROPN
dti-1334	146	37	al	al	PROPN
dti-1334	146	38	.	.	PROPN
dti-1334	146	39	2005	2005	NUM
dti-1334	146	40	;	;	PUNCT
dti-1334	146	41	reid	reid	PROPN
dti-1334	146	42	et	et	PROPN
dti-1334	146	43	al	al	PROPN
dti-1334	146	44	.	.	PROPN
dti-1334	146	45	2007	2007	NUM
dti-1334	146	46	)	)	PUNCT
dti-1334	146	47	.	.	PUNCT
dti-1334	147	1	thus	thus	ADV
dti-1334	147	2	,	,	PUNCT
dti-1334	147	3	protein	protein	NOUN
dti-1334	147	4	arrays	array	NOUN
dti-1334	147	5	represent	represent	VERB
dti-1334	147	6	a	a	DET
dti-1334	147	7	proteomic	proteomic	ADJ
dti-1334	147	8	tool	tool	NOUN
dti-1334	147	9	that	that	PRON
dti-1334	147	10	closely	closely	ADV
dti-1334	147	11	emulates	emulate	VERB
dti-1334	147	12	the	the	DET
dti-1334	147	13	dna	dna	PROPN
dti-1334	147	14	microarray	microarray	PROPN
dti-1334	147	15	technology	technology	NOUN
dti-1334	147	16	.	.	PUNCT
dti-1334	148	1	protein	protein	NOUN
dti-1334	148	2	arrays	array	NOUN
dti-1334	148	3	are	be	AUX
dti-1334	148	4	used	use	VERB
dti-1334	148	5	to	to	PART
dti-1334	148	6	perform	perform	VERB
dti-1334	148	7	protein	protein	NOUN
dti-1334	148	8	expression	expression	NOUN
dti-1334	148	9	profi	profi	PROPN
dti-1334	148	10	ling	ling	PROPN
dti-1334	148	11	,	,	PUNCT
dti-1334	148	12	to	to	PART
dti-1334	148	13	analyze	analyze	VERB
dti-1334	148	14	protein	protein	NOUN
dti-1334	148	15	-	-	PUNCT
dti-1334	148	16	protein	protein	NOUN
dti-1334	148	17	interactions	interaction	NOUN
dti-1334	148	18	,	,	PUNCT
dti-1334	148	19	to	to	PART
dti-1334	148	20	determine	determine	VERB
dti-1334	148	21	the	the	DET
dti-1334	148	22	substrates	substrate	NOUN
dti-1334	148	23	of	of	ADP
dti-1334	148	24	protein	protein	NOUN
dti-1334	148	25	kinases	kinase	NOUN
dti-1334	148	26	,	,	PUNCT
dti-1334	148	27	to	to	PART
dti-1334	148	28	identify	identify	VERB
dti-1334	148	29	the	the	DET
dti-1334	148	30	targets	target	NOUN
dti-1334	148	31	of	of	ADP
dti-1334	148	32	biologically	biologically	ADV
dti-1334	148	33	active	active	ADJ
dti-1334	148	34	small	small	ADJ
dti-1334	148	35	molecules	molecule	NOUN
dti-1334	148	36	,	,	PUNCT
dti-1334	148	37	or	or	CCONJ
dti-1334	148	38	to	to	PART
dti-1334	148	39	detect	detect	VERB
dti-1334	148	40	new	new	ADJ
dti-1334	148	41	disease	disease	NOUN
dti-1334	148	42	biomarkers	biomarker	NOUN
dti-1334	148	43	(	(	PUNCT
dti-1334	148	44	uttamchandani	uttamchandani	PROPN
dti-1334	148	45	et	et	PROPN
dti-1334	148	46	al	al	PROPN
dti-1334	148	47	.	.	PROPN
dti-1334	148	48	2006	2006	NUM
dti-1334	148	49	)	)	PUNCT
dti-1334	148	50	.	.	PUNCT
dti-1334	149	1	one	one	NUM
dti-1334	149	2	of	of	ADP
dti-1334	149	3	the	the	DET
dti-1334	149	4	chief	chief	ADJ
dti-1334	149	5	formats	format	NOUN
dti-1334	149	6	of	of	ADP
dti-1334	149	7	protein	protein	NOUN
dti-1334	149	8	array	array	NOUN
dti-1334	149	9	is	be	AUX
dti-1334	149	10	the	the	DET
dti-1334	149	11	capture	capture	NOUN
dti-1334	149	12	array	array	NOUN
dti-1334	149	13	,	,	PUNCT
dti-1334	149	14	in	in	ADP
dti-1334	149	15	which	which	PRON
dti-1334	149	16	ligand	ligand	NOUN
dti-1334	149	17	-	-	PUNCT
dti-1334	149	18	binding	bind	VERB
dti-1334	149	19	reagents	reagent	NOUN
dti-1334	149	20	,	,	PUNCT
dti-1334	149	21	which	which	PRON
dti-1334	149	22	are	be	AUX
dti-1334	149	23	usually	usually	ADV
dti-1334	149	24	antibodies	antibody	NOUN
dti-1334	149	25	but	but	CCONJ
dti-1334	149	26	may	may	AUX
dti-1334	149	27	also	also	ADV
dti-1334	149	28	be	be	AUX
dti-1334	149	29	alternative	alternative	ADJ
dti-1334	149	30	protein	protein	NOUN
dti-1334	149	31	scaffolds	scaffold	NOUN
dti-1334	149	32	,	,	PUNCT
dti-1334	149	33	peptides	peptide	NOUN
dti-1334	149	34	or	or	CCONJ
dti-1334	149	35	nucleic	nucleic	ADJ
dti-1334	149	36	acid	acid	NOUN
dti-1334	149	37	aptamers	aptamer	NOUN
dti-1334	149	38	,	,	PUNCT
dti-1334	149	39	are	be	AUX
dti-1334	149	40	used	use	VERB
dti-1334	149	41	to	to	PART
dti-1334	149	42	capture	capture	VERB
dti-1334	149	43	target	target	NOUN
dti-1334	149	44	molecules	molecule	NOUN
dti-1334	149	45	in	in	ADP
dti-1334	149	46	mixtures	mixture	NOUN
dti-1334	149	47	such	such	ADJ
dti-1334	149	48	as	as	ADP
dti-1334	149	49	plasma	plasma	NOUN
dti-1334	149	50	or	or	CCONJ
dti-1334	149	51	tissue	tissue	NOUN
dti-1334	149	52	extracts	extract	NOUN
dti-1334	149	53	.	.	PUNCT
dti-1334	150	1	protein	protein	NOUN
dti-1334	150	2	arrays	array	VERB
dti-1334	150	3	using	use	VERB
dti-1334	150	4	antibodies	antibody	NOUN
dti-1334	150	5	as	as	SCONJ
dti-1334	150	6	the	the	DET
dti-1334	150	7	capture	capture	NOUN
dti-1334	150	8	moieties	moiety	NOUN
dti-1334	150	9	are	be	AUX
dti-1334	150	10	called	call	VERB
dti-1334	150	11	antibody	antibody	NOUN
dti-1334	150	12	arrays	array	NOUN
dti-1334	150	13	(	(	PUNCT
dti-1334	150	14	kopf	kopf	NOUN
dti-1334	150	15	and	and	CCONJ
dti-1334	150	16	zharhary	zharhary	ADJ
dti-1334	150	17	,	,	PUNCT
dti-1334	150	18	2007	2007	NUM
dti-1334	150	19	)	)	PUNCT
dti-1334	150	20	,	,	PUNCT
dti-1334	150	21	which	which	PRON
dti-1334	150	22	fall	fall	VERB
dti-1334	150	23	into	into	ADP
dti-1334	150	24	one	one	NUM
dti-1334	150	25	of	of	ADP
dti-1334	150	26	two	two	NUM
dti-1334	150	27	subtypes	subtype	NOUN
dti-1334	150	28	:	:	PUNCT
dti-1334	150	29	those	those	PRON
dti-1334	150	30	using	use	VERB
dti-1334	150	31	matched	match	VERB
dti-1334	150	32	antibody	antibody	NOUN
dti-1334	150	33	pairs	pair	NOUN
dti-1334	150	34	for	for	ADP
dti-1334	150	35	sandwich	sandwich	NOUN
dti-1334	150	36	-	-	PUNCT
dti-1334	150	37	type	type	NOUN
dti-1334	150	38	assays	assay	NOUN
dti-1334	150	39	(	(	PUNCT
dti-1334	150	40	forward	forward	ADJ
dti-1334	150	41	phase	phase	NOUN
dti-1334	150	42	arrays	array	VERB
dti-1334	150	43	)	)	PUNCT
dti-1334	150	44	and	and	CCONJ
dti-1334	150	45	those	those	PRON
dti-1334	150	46	utilizing	utilize	VERB
dti-1334	150	47	single	single	ADJ
dti-1334	150	48	antibodies	antibody	NOUN
dti-1334	150	49	and	and	CCONJ
dti-1334	150	50	a	a	DET
dti-1334	150	51	sample	sample	NOUN
dti-1334	150	52	labeling	labeling	NOUN
dti-1334	150	53	methodology	methodology	NOUN
dti-1334	150	54	(	(	PUNCT
dti-1334	150	55	reverse	reverse	ADJ
dti-1334	150	56	phase	phase	NOUN
dti-1334	150	57	arrays	array	VERB
dti-1334	150	58	)	)	PUNCT
dti-1334	150	59	.	.	PUNCT
dti-1334	151	1	the	the	DET
dti-1334	151	2	former	former	ADJ
dti-1334	151	3	platform	platform	NOUN
dti-1334	151	4	requires	require	VERB
dti-1334	151	5	the	the	DET
dti-1334	151	6	use	use	NOUN
dti-1334	151	7	of	of	ADP
dti-1334	151	8	a	a	DET
dti-1334	151	9	“	"	PUNCT
dti-1334	151	10	detector	detector	NOUN
dti-1334	151	11	”	"	PUNCT
dti-1334	151	12	antibody	antibody	NOUN
dti-1334	151	13	with	with	ADP
dti-1334	151	14	is	be	AUX
dti-1334	151	15	either	either	CCONJ
dti-1334	151	16	modifi	modifi	NOUN
dti-1334	151	17	ed	ed	NOUN
dti-1334	151	18	with	with	ADP
dti-1334	151	19	a	a	DET
dti-1334	151	20	directly	directly	ADV
dti-1334	151	21	detectable	detectable	ADJ
dti-1334	151	22	label	label	NOUN
dti-1334	151	23	(	(	PUNCT
dti-1334	151	24	enzyme	enzyme	NOUN
dti-1334	151	25	,	,	PUNCT
dti-1334	151	26	fluorescent	fluorescent	ADJ
dti-1334	151	27	molecule	molecule	NOUN
dti-1334	151	28	,	,	PUNCT
dti-1334	151	29	isotope	isotope	NOUN
dti-1334	151	30	,	,	PUNCT
dti-1334	151	31	etc	etc	X
dti-1334	151	32	.	.	X
dti-1334	151	33	)	)	PUNCT
dti-1334	151	34	,	,	PUNCT
dti-1334	151	35	or	or	CCONJ
dti-1334	151	36	it	it	PRON
dti-1334	151	37	is	be	AUX
dti-1334	151	38	biotinylated	biotinylate	VERB
dti-1334	151	39	for	for	ADP
dti-1334	151	40	detection	detection	NOUN
dti-1334	151	41	after	after	ADP
dti-1334	151	42	subsequent	subsequent	ADJ
dti-1334	151	43	probing	probe	VERB
dti-1334	151	44	with	with	ADP
dti-1334	151	45	labeled	label	VERB
dti-1334	151	46	streptavidin	streptavidin	NOUN
dti-1334	151	47	.	.	PUNCT
dti-1334	152	1	this	this	DET
dti-1334	152	2	platform	platform	NOUN
dti-1334	152	3	essentially	essentially	ADV
dti-1334	152	4	resembles	resemble	VERB
dti-1334	152	5	elisa	elisa	NOUN
dti-1334	152	6	.	.	PUNCT
dti-1334	153	1	the	the	DET
dti-1334	153	2	latter	latter	ADJ
dti-1334	153	3	requires	require	VERB
dti-1334	153	4	that	that	SCONJ
dti-1334	153	5	protein	protein	NOUN
dti-1334	153	6	samples	sample	NOUN
dti-1334	153	7	be	be	AUX
dti-1334	153	8	labeled	label	VERB
dti-1334	153	9	beforehand	beforehand	ADV
dti-1334	153	10	(	(	PUNCT
dti-1334	153	11	e.g.	e.g.	ADV
dti-1334	153	12	with	with	ADP
dti-1334	153	13	fl	fl	PROPN
dti-1334	153	14	uorescent	uorescent	ADJ
dti-1334	153	15	molecule	molecule	NOUN
dti-1334	153	16	,	,	PUNCT
dti-1334	153	17	isotope	isotope	NOUN
dti-1334	153	18	,	,	PUNCT
dti-1334	153	19	or	or	CCONJ
dti-1334	153	20	biotin	biotin	NOUN
dti-1334	153	21	)	)	PUNCT
dti-1334	153	22	,	,	PUNCT
dti-1334	153	23	thus	thus	ADV
dti-1334	153	24	obviating	obviate	VERB
dti-1334	153	25	use	use	NOUN
dti-1334	153	26	of	of	ADP
dti-1334	153	27	a	a	DET
dti-1334	153	28	detector	detector	NOUN
dti-1334	153	29	antibody	antibody	NOUN
dti-1334	153	30	.	.	PUNCT
dti-1334	154	1	antibody	antibody	NOUN
dti-1334	154	2	array	array	NOUN
dti-1334	154	3	technology	technology	NOUN
dti-1334	154	4	is	be	AUX
dti-1334	154	5	attracting	attract	VERB
dti-1334	154	6	61	61	NUM
dti-1334	154	7	proteomics	proteomic	NOUN
dti-1334	154	8	in	in	ADP
dti-1334	154	9	personalized	personalized	ADJ
dti-1334	154	10	cancer	cancer	NOUN
dti-1334	154	11	therapy	therapy	NOUN
dti-1334	154	12	drug	drug	NOUN
dti-1334	154	13	target	target	NOUN
dti-1334	154	14	insights	insight	NOUN
dti-1334	154	15	2008:3	2008:3	NUM
dti-1334	154	16	a	a	DET
dti-1334	154	17	lot	lot	NOUN
dti-1334	154	18	of	of	ADP
dti-1334	154	19	attention	attention	NOUN
dti-1334	154	20	because	because	SCONJ
dti-1334	154	21	of	of	ADP
dti-1334	154	22	the	the	DET
dti-1334	154	23	potential	potential	NOUN
dti-1334	154	24	of	of	ADP
dti-1334	154	25	analyzing	analyze	VERB
dti-1334	154	26	the	the	DET
dti-1334	154	27	levels	level	NOUN
dti-1334	154	28	of	of	ADP
dti-1334	154	29	hundreds	hundred	NOUN
dti-1334	154	30	of	of	ADP
dti-1334	154	31	proteins	protein	NOUN
dti-1334	154	32	within	within	ADP
dti-1334	154	33	a	a	DET
dti-1334	154	34	pathway	pathway	NOUN
dti-1334	154	35	of	of	ADP
dti-1334	154	36	interest	interest	NOUN
dti-1334	154	37	(	(	PUNCT
dti-1334	154	38	borrebaeck	borrebaeck	NOUN
dti-1334	154	39	,	,	PUNCT
dti-1334	154	40	2006	2006	NUM
dti-1334	154	41	)	)	PUNCT
dti-1334	154	42	.	.	PUNCT
dti-1334	155	1	when	when	SCONJ
dti-1334	155	2	other	other	ADJ
dti-1334	155	3	ligand	ligand	NOUN
dti-1334	155	4	-	-	PUNCT
dti-1334	155	5	binding	bind	VERB
dti-1334	155	6	molecules	molecule	NOUN
dti-1334	155	7	are	be	AUX
dti-1334	155	8	used	use	VERB
dti-1334	155	9	,	,	PUNCT
dti-1334	155	10	the	the	DET
dti-1334	155	11	capture	capture	NOUN
dti-1334	155	12	arrays	array	VERB
dti-1334	155	13	can	can	AUX
dti-1334	155	14	be	be	AUX
dti-1334	155	15	used	use	VERB
dti-1334	155	16	to	to	PART
dti-1334	155	17	study	study	VERB
dti-1334	155	18	functional	functional	ADJ
dti-1334	155	19	proteomics	proteomic	NOUN
dti-1334	155	20	such	such	ADJ
dti-1334	155	21	as	as	ADP
dti-1334	155	22	protein	protein	NOUN
dti-1334	155	23	-	-	PUNCT
dti-1334	155	24	protein	protein	NOUN
dti-1334	155	25	,	,	PUNCT
dti-1334	155	26	protein	protein	NOUN
dti-1334	155	27	-	-	PUNCT
dti-1334	155	28	dna	dna	NOUN
dti-1334	155	29	,	,	PUNCT
dti-1334	155	30	protein	protein	NOUN
dti-1334	155	31	-	-	PUNCT
dti-1334	155	32	drug	drug	NOUN
dti-1334	155	33	,	,	PUNCT
dti-1334	155	34	receptor	receptor	NOUN
dti-1334	155	35	-	-	PUNCT
dti-1334	155	36	ligand	ligand	NOUN
dti-1334	155	37	,	,	PUNCT
dti-1334	155	38	enzyme	enzyme	NOUN
dti-1334	155	39	-	-	PUNCT
dti-1334	155	40	substrate	substrate	NOUN
dti-1334	155	41	interactions	interaction	NOUN
dti-1334	155	42	,	,	PUNCT
dti-1334	155	43	etc	etc	X
dti-1334	155	44	.	.	X
dti-1334	156	1	(	(	PUNCT
dti-1334	156	2	cho	cho	NOUN
dti-1334	156	3	and	and	CCONJ
dti-1334	156	4	cheng	cheng	PROPN
dti-1334	156	5	,	,	PUNCT
dti-1334	156	6	2007	2007	NUM
dti-1334	156	7	)	)	PUNCT
dti-1334	156	8	.	.	PUNCT
dti-1334	157	1	they	they	PRON
dti-1334	157	2	may	may	AUX
dti-1334	157	3	also	also	ADV
dti-1334	157	4	be	be	AUX
dti-1334	157	5	used	use	VERB
dti-1334	157	6	to	to	PART
dti-1334	157	7	correlate	correlate	VERB
dti-1334	157	8	the	the	DET
dti-1334	157	9	polymorphic	polymorphic	ADJ
dti-1334	157	10	changes	change	NOUN
dti-1334	157	11	resulting	result	VERB
dti-1334	157	12	from	from	ADP
dti-1334	157	13	snps	snps	PROPN
dti-1334	157	14	with	with	ADP
dti-1334	157	15	protein	protein	NOUN
dti-1334	157	16	function	function	NOUN
dti-1334	157	17	.	.	PUNCT
dti-1334	158	1	the	the	DET
dti-1334	158	2	capture	capture	NOUN
dti-1334	158	3	reagents	reagent	VERB
dti-1334	158	4	themselves	themselves	PRON
dti-1334	158	5	will	will	AUX
dti-1334	158	6	need	need	VERB
dti-1334	158	7	to	to	PART
dti-1334	158	8	be	be	AUX
dti-1334	158	9	selected	select	VERB
dti-1334	158	10	and	and	CCONJ
dti-1334	158	11	screened	screen	VERB
dti-1334	158	12	against	against	ADP
dti-1334	158	13	many	many	ADJ
dti-1334	158	14	proteins	protein	NOUN
dti-1334	158	15	,	,	PUNCT
dti-1334	158	16	which	which	PRON
dti-1334	158	17	can	can	AUX
dti-1334	158	18	also	also	ADV
dti-1334	158	19	be	be	AUX
dti-1334	158	20	done	do	VERB
dti-1334	158	21	in	in	ADP
dti-1334	158	22	a	a	DET
dti-1334	158	23	multiplex	multiplex	PROPN
dti-1334	158	24	array	array	NOUN
dti-1334	158	25	format	format	NOUN
dti-1334	158	26	against	against	ADP
dti-1334	158	27	multiple	multiple	ADJ
dti-1334	158	28	protein	protein	NOUN
dti-1334	158	29	targets	target	NOUN
dti-1334	158	30	.	.	PUNCT
dti-1334	159	1	another	another	DET
dti-1334	159	2	protein	protein	NOUN
dti-1334	159	3	array	array	NOUN
dti-1334	159	4	platform	platform	NOUN
dti-1334	159	5	,	,	PUNCT
dti-1334	159	6	known	know	VERB
dti-1334	159	7	as	as	ADP
dti-1334	159	8	profusion	profusion	NOUN
dti-1334	159	9	™	™	PROPN
dti-1334	159	10	(	(	PUNCT
dti-1334	159	11	phylos	phylos	PROPN
dti-1334	159	12	,	,	PUNCT
dti-1334	159	13	inc	inc	PROPN
dti-1334	159	14	.	.	PROPN
dti-1334	159	15	,	,	PUNCT
dti-1334	159	16	lexington	lexington	PROPN
dti-1334	159	17	,	,	PUNCT
dti-1334	159	18	ma	ma	PROPN
dti-1334	159	19	)	)	PUNCT
dti-1334	159	20	arrays	array	VERB
dti-1334	159	21	,	,	PUNCT
dti-1334	159	22	utilizes	utilize	VERB
dti-1334	159	23	surface	surface	NOUN
dti-1334	159	24	-	-	PUNCT
dti-1334	159	25	bound	bind	VERB
dti-1334	159	26	dna	dna	NOUN
dti-1334	159	27	probes	probe	NOUN
dti-1334	159	28	that	that	PRON
dti-1334	159	29	hybridize	hybridize	VERB
dti-1334	159	30	to	to	ADP
dti-1334	159	31	a	a	DET
dti-1334	159	32	protein	protein	NOUN
dti-1334	159	33	via	via	ADP
dti-1334	159	34	its	its	PRON
dti-1334	159	35	encoding	encoding	NOUN
dti-1334	159	36	mrna	mrna	PROPN
dti-1334	159	37	.	.	PUNCT
dti-1334	160	1	taken	take	VERB
dti-1334	160	2	together	together	ADV
dti-1334	160	3	,	,	PUNCT
dti-1334	160	4	these	these	DET
dti-1334	160	5	protein	protein	NOUN
dti-1334	160	6	array	array	NOUN
dti-1334	160	7	technologies	technology	NOUN
dti-1334	160	8	offer	offer	VERB
dti-1334	160	9	advantages	advantage	NOUN
dti-1334	160	10	include	include	VERB
dti-1334	160	11	being	be	AUX
dti-1334	160	12	rapid	rapid	ADJ
dti-1334	160	13	and	and	CCONJ
dti-1334	160	14	automatable	automatable	ADJ
dti-1334	160	15	,	,	PUNCT
dti-1334	160	16	capable	capable	ADJ
dti-1334	160	17	of	of	ADP
dti-1334	160	18	high	high	ADJ
dti-1334	160	19	sensitivity	sensitivity	NOUN
dti-1334	160	20	,	,	PUNCT
dti-1334	160	21	economical	economical	ADJ
dti-1334	160	22	on	on	ADP
dti-1334	160	23	reagents	reagent	NOUN
dti-1334	160	24	,	,	PUNCT
dti-1334	160	25	and	and	CCONJ
dti-1334	160	26	giving	give	VERB
dti-1334	160	27	an	an	DET
dti-1334	160	28	abundance	abundance	NOUN
dti-1334	160	29	of	of	ADP
dti-1334	160	30	data	datum	NOUN
dti-1334	160	31	for	for	ADP
dti-1334	160	32	a	a	DET
dti-1334	160	33	single	single	ADJ
dti-1334	160	34	experiment	experiment	NOUN
dti-1334	160	35	(	(	PUNCT
dti-1334	160	36	becker	becker	PROPN
dti-1334	160	37	et	et	PROPN
dti-1334	160	38	al	al	PROPN
dti-1334	160	39	.	.	PROPN
dti-1334	160	40	2006	2006	NUM
dti-1334	160	41	;	;	PUNCT
dti-1334	160	42	hall	hall	NOUN
dti-1334	160	43	et	et	PROPN
dti-1334	160	44	al	al	PROPN
dti-1334	160	45	.	.	PROPN
dti-1334	160	46	2007	2007	NUM
dti-1334	160	47	)	)	PUNCT
dti-1334	160	48	.	.	PUNCT
dti-1334	161	1	however	however	ADV
dti-1334	161	2	,	,	PUNCT
dti-1334	161	3	the	the	DET
dti-1334	161	4	potential	potential	NOUN
dti-1334	161	5	of	of	ADP
dti-1334	161	6	antibody	antibody	NOUN
dti-1334	161	7	arrays	array	VERB
dti-1334	161	8	is	be	AUX
dti-1334	161	9	currently	currently	ADV
dti-1334	161	10	limited	limit	VERB
dti-1334	161	11	by	by	ADP
dti-1334	161	12	the	the	DET
dti-1334	161	13	high	high	ADJ
dti-1334	161	14	cost	cost	NOUN
dti-1334	161	15	of	of	ADP
dti-1334	161	16	producing	produce	VERB
dti-1334	161	17	antibodies	antibody	NOUN
dti-1334	161	18	and	and	CCONJ
dti-1334	161	19	the	the	DET
dti-1334	161	20	availability	availability	NOUN
dti-1334	161	21	of	of	ADP
dti-1334	161	22	antibodies	antibody	NOUN
dti-1334	161	23	that	that	PRON
dti-1334	161	24	have	have	VERB
dti-1334	161	25	both	both	CCONJ
dti-1334	161	26	high	high	ADJ
dti-1334	161	27	specifi	specifi	PROPN
dti-1334	161	28	city	city	PROPN
dti-1334	161	29	(	(	PUNCT
dti-1334	161	30	to	to	PART
dti-1334	161	31	eliminate	eliminate	VERB
dti-1334	161	32	cross	cross	ADJ
dti-1334	161	33	reactions	reaction	NOUN
dti-1334	161	34	with	with	ADP
dti-1334	161	35	non	non	ADJ
dti-1334	161	36	-	-	ADJ
dti-1334	161	37	specifi	specifi	ADJ
dti-1334	161	38	c	c	NOUN
dti-1334	161	39	proteins	protein	NOUN
dti-1334	161	40	within	within	ADP
dti-1334	161	41	the	the	DET
dti-1334	161	42	sample	sample	NOUN
dti-1334	161	43	)	)	PUNCT
dti-1334	161	44	and	and	CCONJ
dti-1334	161	45	high	high	ADJ
dti-1334	161	46	affi	affi	PROPN
dti-1334	161	47	nity	nity	NOUN
dti-1334	161	48	for	for	ADP
dti-1334	161	49	the	the	DET
dti-1334	161	50	target	target	NOUN
dti-1334	161	51	of	of	ADP
dti-1334	161	52	interest	interest	NOUN
dti-1334	161	53	(	(	PUNCT
dti-1334	161	54	to	to	PART
dti-1334	161	55	allow	allow	VERB
dti-1334	161	56	detection	detection	NOUN
dti-1334	161	57	of	of	ADP
dti-1334	161	58	small	small	ADJ
dti-1334	161	59	quantities	quantity	NOUN
dti-1334	161	60	within	within	ADP
dti-1334	161	61	a	a	DET
dti-1334	161	62	sample	sample	NOUN
dti-1334	161	63	)	)	PUNCT
dti-1334	161	64	.	.	PUNCT
dti-1334	162	1	additionally	additionally	ADV
dti-1334	162	2	,	,	PUNCT
dti-1334	162	3	the	the	DET
dti-1334	162	4	diffi	diffi	PROPN
dti-1334	162	5	culty	culty	NOUN
dti-1334	162	6	associated	associate	VERB
dti-1334	162	7	with	with	ADP
dti-1334	162	8	preserving	preserve	VERB
dti-1334	162	9	proteins	protein	NOUN
dti-1334	162	10	in	in	ADP
dti-1334	162	11	their	their	PRON
dti-1334	162	12	biologically	biologically	ADV
dti-1334	162	13	active	active	ADJ
dti-1334	162	14	conformation	conformation	NOUN
dti-1334	162	15	before	before	ADP
dti-1334	162	16	analysis	analysis	NOUN
dti-1334	162	17	with	with	ADP
dti-1334	162	18	protein	protein	NOUN
dti-1334	162	19	arrays	array	VERB
dti-1334	162	20	further	further	ADJ
dti-1334	162	21	limits	limit	VERB
dti-1334	162	22	the	the	DET
dti-1334	162	23	application	application	NOUN
dti-1334	162	24	of	of	ADP
dti-1334	162	25	this	this	DET
dti-1334	162	26	technology	technology	NOUN
dti-1334	162	27	as	as	ADP
dti-1334	162	28	a	a	DET
dti-1334	162	29	routine	routine	ADJ
dti-1334	162	30	proteomic	proteomic	ADJ
dti-1334	162	31	strategy	strategy	NOUN
dti-1334	162	32	.	.	PUNCT
dti-1334	163	1	given	give	VERB
dti-1334	163	2	the	the	DET
dti-1334	163	3	amount	amount	NOUN
dti-1334	163	4	of	of	ADP
dti-1334	163	5	information	information	NOUN
dti-1334	163	6	generated	generate	VERB
dti-1334	163	7	from	from	ADP
dti-1334	163	8	one	one	NUM
dti-1334	163	9	experiment	experiment	NOUN
dti-1334	163	10	,	,	PUNCT
dti-1334	163	11	significant	significant	ADJ
dti-1334	163	12	input	input	NOUN
dti-1334	163	13	of	of	ADP
dti-1334	163	14	bioinformatics	bioinformatics	NOUN
dti-1334	163	15	support	support	NOUN
dti-1334	163	16	is	be	AUX
dti-1334	163	17	important	important	ADJ
dti-1334	163	18	;	;	PUNCT
dti-1334	163	19	the	the	DET
dti-1334	163	20	data	datum	NOUN
dti-1334	163	21	handling	handle	VERB
dti-1334	163	22	demands	demand	VERB
dti-1334	163	23	sophisticated	sophisticated	ADJ
dti-1334	163	24	software	software	NOUN
dti-1334	163	25	and	and	CCONJ
dti-1334	163	26	data	datum	NOUN
dti-1334	163	27	comparison	comparison	NOUN
dti-1334	163	28	analysis	analysis	NOUN
dti-1334	163	29	.	.	PUNCT
dti-1334	164	1	fortunately	fortunately	ADV
dti-1334	164	2	some	some	PRON
dti-1334	164	3	of	of	ADP
dti-1334	164	4	the	the	DET
dti-1334	164	5	software	software	NOUN
dti-1334	164	6	can	can	AUX
dti-1334	164	7	be	be	AUX
dti-1334	164	8	adapted	adapt	VERB
dti-1334	164	9	from	from	ADP
dti-1334	164	10	that	that	PRON
dti-1334	164	11	used	use	VERB
dti-1334	164	12	for	for	ADP
dti-1334	164	13	dna	dna	PROPN
dti-1334	164	14	arrays	array	VERB
dti-1334	164	15	,	,	PUNCT
dti-1334	164	16	as	as	SCONJ
dti-1334	164	17	can	can	AUX
dti-1334	164	18	much	much	ADJ
dti-1334	164	19	of	of	ADP
dti-1334	164	20	the	the	DET
dti-1334	164	21	hardware	hardware	NOUN
dti-1334	164	22	and	and	CCONJ
dti-1334	164	23	detection	detection	NOUN
dti-1334	164	24	systems	system	NOUN
dti-1334	164	25	.	.	PUNCT
dti-1334	165	1	laser	laser	NOUN
dti-1334	165	2	capture	capture	NOUN
dti-1334	165	3	microdissection	microdissection	NOUN
dti-1334	165	4	(	(	PUNCT
dti-1334	165	5	lcm	lcm	NOUN
dti-1334	165	6	)	)	PUNCT
dti-1334	165	7	the	the	DET
dti-1334	165	8	power	power	NOUN
dti-1334	165	9	of	of	ADP
dti-1334	165	10	proteomic	proteomic	ADJ
dti-1334	165	11	analytical	analytical	ADJ
dti-1334	165	12	techniques	technique	NOUN
dti-1334	165	13	relies	rely	VERB
dti-1334	165	14	heavily	heavily	ADV
dti-1334	165	15	on	on	ADP
dti-1334	165	16	the	the	DET
dti-1334	165	17	preparation	preparation	NOUN
dti-1334	165	18	of	of	ADP
dti-1334	165	19	homogeneous	homogeneous	ADJ
dti-1334	165	20	cell	cell	NOUN
dti-1334	165	21	populations	population	NOUN
dti-1334	165	22	.	.	PUNCT
dti-1334	166	1	tumors	tumor	NOUN
dti-1334	166	2	are	be	AUX
dti-1334	166	3	heterogeneous	heterogeneous	ADJ
dti-1334	166	4	microenvironments	microenvironment	NOUN
dti-1334	166	5	comprised	comprise	VERB
dti-1334	166	6	of	of	ADP
dti-1334	166	7	stroma	stroma	ADJ
dti-1334	166	8	,	,	PUNCT
dti-1334	166	9	normal	normal	ADJ
dti-1334	166	10	cells	cell	NOUN
dti-1334	166	11	,	,	PUNCT
dti-1334	166	12	and	and	CCONJ
dti-1334	166	13	cancer	cancer	NOUN
dti-1334	166	14	cells	cell	NOUN
dti-1334	166	15	at	at	ADP
dti-1334	166	16	various	various	ADJ
dti-1334	166	17	stages	stage	NOUN
dti-1334	166	18	of	of	ADP
dti-1334	166	19	differentiation	differentiation	NOUN
dti-1334	166	20	.	.	PUNCT
dti-1334	167	1	identifi	identifi	PROPN
dti-1334	167	2	cation	cation	NOUN
dti-1334	167	3	of	of	ADP
dti-1334	167	4	protein	protein	NOUN
dti-1334	167	5	level	level	NOUN
dti-1334	167	6	changes	change	NOUN
dti-1334	167	7	specifi	specifi	X
dti-1334	167	8	c	c	PROPN
dti-1334	167	9	to	to	ADP
dti-1334	167	10	cancer	cancer	NOUN
dti-1334	167	11	cells	cell	NOUN
dti-1334	167	12	is	be	AUX
dti-1334	167	13	hampered	hamper	VERB
dti-1334	167	14	by	by	ADP
dti-1334	167	15	the	the	DET
dti-1334	167	16	composite	composite	ADJ
dti-1334	167	17	interspersed	intersperse	VERB
dti-1334	167	18	cell	cell	NOUN
dti-1334	167	19	subpopulations	subpopulation	NOUN
dti-1334	167	20	in	in	ADP
dti-1334	167	21	acquired	acquire	VERB
dti-1334	167	22	tissue	tissue	NOUN
dti-1334	167	23	specimens	specimen	NOUN
dti-1334	167	24	.	.	PUNCT
dti-1334	168	1	in	in	ADP
dti-1334	168	2	order	order	NOUN
dti-1334	168	3	to	to	PART
dti-1334	168	4	overcome	overcome	VERB
dti-1334	168	5	this	this	DET
dti-1334	168	6	diffi	diffi	PROPN
dti-1334	168	7	culty	culty	PROPN
dti-1334	168	8	,	,	PUNCT
dti-1334	168	9	michael	michael	PROPN
dti-1334	168	10	emmert	emmert	PROPN
dti-1334	168	11	-	-	PUNCT
dti-1334	168	12	buck	buck	NOUN
dti-1334	168	13	and	and	CCONJ
dti-1334	168	14	colleagues	colleague	NOUN
dti-1334	168	15	(	(	PUNCT
dti-1334	168	16	emmert	emmert	NOUN
dti-1334	168	17	-	-	PUNCT
dti-1334	168	18	buck	buck	NOUN
dti-1334	168	19	et	et	PROPN
dti-1334	168	20	al	al	PROPN
dti-1334	168	21	.	.	PROPN
dti-1334	168	22	1996	1996	NUM
dti-1334	168	23	;	;	PUNCT
dti-1334	168	24	emmertbuck	emmertbuck	VERB
dti-1334	168	25	et	et	PROPN
dti-1334	168	26	al	al	PROPN
dti-1334	168	27	.	.	PROPN
dti-1334	168	28	1994	1994	NUM
dti-1334	168	29	)	)	PUNCT
dti-1334	168	30	at	at	ADP
dti-1334	168	31	the	the	DET
dti-1334	168	32	national	national	PROPN
dti-1334	168	33	institutes	institutes	PROPN
dti-1334	168	34	of	of	ADP
dti-1334	168	35	health	health	PROPN
dti-1334	168	36	(	(	PUNCT
dti-1334	168	37	nih	nih	PROPN
dti-1334	168	38	)	)	PUNCT
dti-1334	168	39	developed	develop	VERB
dti-1334	168	40	lcm	lcm	NOUN
dti-1334	168	41	and	and	CCONJ
dti-1334	168	42	demonstrated	demonstrate	VERB
dti-1334	168	43	its	its	PRON
dti-1334	168	44	usefulness	usefulness	NOUN
dti-1334	168	45	for	for	ADP
dti-1334	168	46	studying	study	VERB
dti-1334	168	47	various	various	ADJ
dti-1334	168	48	tissue	tissue	NOUN
dti-1334	168	49	types	type	NOUN
dti-1334	168	50	at	at	ADP
dti-1334	168	51	the	the	DET
dti-1334	168	52	dna	dna	PROPN
dti-1334	168	53	,	,	PUNCT
dti-1334	168	54	mrna	mrna	PROPN
dti-1334	168	55	,	,	PUNCT
dti-1334	168	56	and	and	CCONJ
dti-1334	168	57	protein	protein	NOUN
dti-1334	168	58	levels	level	NOUN
dti-1334	168	59	.	.	PUNCT
dti-1334	169	1	lcm	lcm	NOUN
dti-1334	169	2	technology	technology	NOUN
dti-1334	169	3	allows	allow	VERB
dti-1334	169	4	researchers	researcher	NOUN
dti-1334	169	5	to	to	PART
dti-1334	169	6	isolate	isolate	VERB
dti-1334	169	7	distinct	distinct	ADJ
dti-1334	169	8	cell	cell	NOUN
dti-1334	169	9	subpopulations	subpopulation	NOUN
dti-1334	169	10	from	from	ADP
dti-1334	169	11	stained	stain	VERB
dti-1334	169	12	tumor	tumor	NOUN
dti-1334	169	13	sections	section	NOUN
dti-1334	169	14	.	.	PUNCT
dti-1334	170	1	tissue	tissue	NOUN
dti-1334	170	2	sections	section	NOUN
dti-1334	170	3	are	be	AUX
dti-1334	170	4	mounted	mount	VERB
dti-1334	170	5	on	on	ADP
dti-1334	170	6	standard	standard	ADJ
dti-1334	170	7	glass	glass	NOUN
dti-1334	170	8	slides	slide	NOUN
dti-1334	170	9	.	.	PUNCT
dti-1334	171	1	a	a	DET
dti-1334	171	2	transparent	transparent	ADJ
dti-1334	171	3	,	,	PUNCT
dti-1334	171	4	100	100	NUM
dti-1334	171	5	-	-	PUNCT
dti-1334	171	6	mm	mm	NOUN
dti-1334	171	7	-	-	PUNCT
dti-1334	171	8	thick	thick	ADJ
dti-1334	171	9	,	,	PUNCT
dti-1334	171	10	ethylene	ethylene	NOUN
dti-1334	171	11	—	—	PUNCT
dti-1334	171	12	vinyl	vinyl	NOUN
dti-1334	171	13	acetate	acetate	NOUN
dti-1334	171	14	fi	fi	NOUN
dti-1334	171	15	lm	lm	INTJ
dti-1334	171	16	is	be	AUX
dti-1334	171	17	then	then	ADV
dti-1334	171	18	placed	place	VERB
dti-1334	171	19	over	over	ADP
dti-1334	171	20	the	the	DET
dti-1334	171	21	dry	dry	ADJ
dti-1334	171	22	section	section	NOUN
dti-1334	171	23	(	(	PUNCT
dti-1334	171	24	bonner	bonner	PROPN
dti-1334	171	25	et	et	PROPN
dti-1334	171	26	al	al	PROPN
dti-1334	171	27	.	.	PROPN
dti-1334	171	28	1997	1997	NUM
dti-1334	171	29	)	)	PUNCT
dti-1334	171	30	.	.	PUNCT
dti-1334	172	1	during	during	ADP
dti-1334	172	2	lcm	lcm	NOUN
dti-1334	172	3	,	,	PUNCT
dti-1334	172	4	cells	cell	NOUN
dti-1334	172	5	are	be	AUX
dti-1334	172	6	isolated	isolate	VERB
dti-1334	172	7	using	use	VERB
dti-1334	172	8	an	an	DET
dti-1334	172	9	inverted	inverted	ADJ
dti-1334	172	10	microscope	microscope	NOUN
dti-1334	172	11	fi	fi	NOUN
dti-1334	172	12	tted	tte	VERB
dti-1334	172	13	with	with	ADP
dti-1334	172	14	a	a	DET
dti-1334	172	15	low	low	ADJ
dti-1334	172	16	-	-	PUNCT
dti-1334	172	17	power	power	NOUN
dti-1334	172	18	near	near	ADP
dti-1334	172	19	-	-	PUNCT
dti-1334	172	20	infrared	infrared	ADJ
dti-1334	172	21	laser	laser	NOUN
dti-1334	172	22	.	.	PUNCT
dti-1334	173	1	the	the	DET
dti-1334	173	2	laser	laser	NOUN
dti-1334	173	3	provides	provide	VERB
dti-1334	173	4	enough	enough	ADJ
dti-1334	173	5	energy	energy	NOUN
dti-1334	173	6	to	to	PART
dti-1334	173	7	transiently	transiently	ADV
dti-1334	173	8	melt	melt	VERB
dti-1334	173	9	this	this	DET
dti-1334	173	10	thermoplastic	thermoplastic	ADJ
dti-1334	173	11	fi	fi	NOUN
dti-1334	173	12	lm	lm	INTJ
dti-1334	173	13	(	(	PUNCT
dti-1334	173	14	momentarily	momentarily	ADV
dti-1334	173	15	heats	heat	VERB
dti-1334	173	16	to	to	ADP
dti-1334	173	17	90	90	NUM
dti-1334	173	18	oc	oc	NOUN
dti-1334	173	19	)	)	PUNCT
dti-1334	173	20	in	in	ADP
dti-1334	173	21	a	a	DET
dti-1334	173	22	precise	precise	ADJ
dti-1334	173	23	location	location	NOUN
dti-1334	173	24	,	,	PUNCT
dti-1334	173	25	binding	bind	VERB
dti-1334	173	26	it	it	PRON
dti-1334	173	27	to	to	ADP
dti-1334	173	28	the	the	DET
dti-1334	173	29	underlying	underlie	VERB
dti-1334	173	30	cells	cell	NOUN
dti-1334	173	31	in	in	ADP
dti-1334	173	32	that	that	DET
dti-1334	173	33	location	location	NOUN
dti-1334	173	34	.	.	PUNCT
dti-1334	174	1	to	to	PART
dti-1334	174	2	improve	improve	VERB
dti-1334	174	3	the	the	DET
dti-1334	174	4	convenience	convenience	NOUN
dti-1334	174	5	of	of	ADP
dti-1334	174	6	the	the	DET
dti-1334	174	7	technique	technique	NOUN
dti-1334	174	8	,	,	PUNCT
dti-1334	174	9	the	the	DET
dti-1334	174	10	transfer	transfer	NOUN
dti-1334	174	11	fi	fi	NOUN
dti-1334	174	12	lm	lm	INTJ
dti-1334	174	13	is	be	AUX
dti-1334	174	14	usually	usually	ADV
dti-1334	174	15	mounted	mount	VERB
dti-1334	174	16	on	on	ADP
dti-1334	174	17	a	a	DET
dti-1334	174	18	transparent	transparent	ADJ
dti-1334	174	19	cap	cap	NOUN
dti-1334	174	20	.	.	PUNCT
dti-1334	175	1	after	after	SCONJ
dti-1334	175	2	the	the	DET
dti-1334	175	3	appropriate	appropriate	ADJ
dti-1334	175	4	cells	cell	NOUN
dti-1334	175	5	have	have	AUX
dti-1334	175	6	been	be	AUX
dti-1334	175	7	selected	select	VERB
dti-1334	175	8	,	,	PUNCT
dti-1334	175	9	the	the	DET
dti-1334	175	10	film	film	NOUN
dti-1334	175	11	and	and	CCONJ
dti-1334	175	12	adherent	adherent	NOUN
dti-1334	175	13	cells	cell	NOUN
dti-1334	175	14	are	be	AUX
dti-1334	175	15	removed	remove	VERB
dti-1334	175	16	,	,	PUNCT
dti-1334	175	17	and	and	CCONJ
dti-1334	175	18	the	the	DET
dti-1334	175	19	unselected	unselected	ADJ
dti-1334	175	20	tissue	tissue	NOUN
dti-1334	175	21	remains	remain	VERB
dti-1334	175	22	in	in	ADP
dti-1334	175	23	contact	contact	NOUN
dti-1334	175	24	with	with	ADP
dti-1334	175	25	the	the	DET
dti-1334	175	26	glass	glass	NOUN
dti-1334	175	27	slide	slide	NOUN
dti-1334	175	28	.	.	PUNCT
dti-1334	176	1	the	the	DET
dti-1334	176	2	laser	laser	NOUN
dti-1334	176	3	diameter	diameter	NOUN
dti-1334	176	4	can	can	AUX
dti-1334	176	5	be	be	AUX
dti-1334	176	6	adjusted	adjust	VERB
dti-1334	176	7	from	from	ADP
dti-1334	176	8	7.5	7.5	NUM
dti-1334	176	9	to	to	PART
dti-1334	176	10	30	30	NUM
dti-1334	176	11	µm	µm	NOUN
dti-1334	176	12	so	so	SCONJ
dti-1334	176	13	that	that	SCONJ
dti-1334	176	14	individual	individual	ADJ
dti-1334	176	15	cells	cell	NOUN
dti-1334	176	16	or	or	CCONJ
dti-1334	176	17	a	a	DET
dti-1334	176	18	cluster	cluster	NOUN
dti-1334	176	19	of	of	ADP
dti-1334	176	20	cells	cell	NOUN
dti-1334	176	21	can	can	AUX
dti-1334	176	22	be	be	AUX
dti-1334	176	23	selected	select	VERB
dti-1334	176	24	.	.	PUNCT
dti-1334	177	1	the	the	DET
dti-1334	177	2	fi	fi	NOUN
dti-1334	177	3	lm	lm	X
dti-1334	177	4	holding	hold	VERB
dti-1334	177	5	the	the	DET
dti-1334	177	6	captured	capture	VERB
dti-1334	177	7	cells	cell	NOUN
dti-1334	177	8	is	be	AUX
dti-1334	177	9	then	then	ADV
dti-1334	177	10	transferred	transfer	VERB
dti-1334	177	11	to	to	ADP
dti-1334	177	12	a	a	DET
dti-1334	177	13	tube	tube	NOUN
dti-1334	177	14	,	,	PUNCT
dti-1334	177	15	where	where	SCONJ
dti-1334	177	16	an	an	DET
dti-1334	177	17	extraction	extraction	NOUN
dti-1334	177	18	buffer	buffer	NOUN
dti-1334	177	19	is	be	AUX
dti-1334	177	20	used	use	VERB
dti-1334	177	21	to	to	PART
dti-1334	177	22	remove	remove	VERB
dti-1334	177	23	the	the	DET
dti-1334	177	24	cells	cell	NOUN
dti-1334	177	25	for	for	ADP
dti-1334	177	26	further	further	ADJ
dti-1334	177	27	molecular	molecular	ADJ
dti-1334	177	28	analysis	analysis	NOUN
dti-1334	177	29	.	.	PUNCT
dti-1334	178	1	up	up	ADP
dti-1334	178	2	to	to	PART
dti-1334	178	3	3000	3000	NUM
dti-1334	178	4	transfers	transfer	NOUN
dti-1334	178	5	can	can	AUX
dti-1334	178	6	be	be	AUX
dti-1334	178	7	performed	perform	VERB
dti-1334	178	8	on	on	ADP
dti-1334	178	9	one	one	NUM
dti-1334	178	10	fi	fi	NOUN
dti-1334	178	11	lm	lm	INTJ
dti-1334	178	12	.	.	PUNCT
dti-1334	179	1	therefore	therefore	ADV
dti-1334	179	2	,	,	PUNCT
dti-1334	179	3	up	up	ADP
dti-1334	179	4	to	to	PART
dti-1334	179	5	3,000–5,000	3,000–5,000	NUM
dti-1334	179	6	cells	cell	NOUN
dti-1334	179	7	can	can	AUX
dti-1334	179	8	be	be	AUX
dti-1334	179	9	isolated	isolate	VERB
dti-1334	179	10	from	from	ADP
dti-1334	179	11	a	a	DET
dti-1334	179	12	single	single	ADJ
dti-1334	179	13	slide	slide	NOUN
dti-1334	179	14	in	in	ADP
dti-1334	179	15	this	this	DET
dti-1334	179	16	fashion	fashion	NOUN
dti-1334	179	17	(	(	PUNCT
dti-1334	179	18	simone	simone	NOUN
dti-1334	179	19	et	et	PROPN
dti-1334	179	20	al	al	PROPN
dti-1334	179	21	.	.	PROPN
dti-1334	179	22	1998	1998	NUM
dti-1334	179	23	)	)	PUNCT
dti-1334	179	24	.	.	PUNCT
dti-1334	180	1	because	because	SCONJ
dti-1334	180	2	the	the	DET
dti-1334	180	3	plastic	plastic	ADJ
dti-1334	180	4	fi	fi	NOUN
dti-1334	180	5	lm	lm	INTJ
dti-1334	180	6	absorbs	absorb	VERB
dti-1334	180	7	most	most	ADJ
dti-1334	180	8	of	of	ADP
dti-1334	180	9	the	the	DET
dti-1334	180	10	thermal	thermal	ADJ
dti-1334	180	11	energy	energy	NOUN
dti-1334	180	12	and	and	CCONJ
dti-1334	180	13	the	the	DET
dti-1334	180	14	pulse	pulse	NOUN
dti-1334	180	15	lasts	last	VERB
dti-1334	180	16	for	for	ADP
dti-1334	180	17	only	only	ADV
dti-1334	180	18	a	a	DET
dti-1334	180	19	fraction	fraction	NOUN
dti-1334	180	20	of	of	ADP
dti-1334	180	21	a	a	DET
dti-1334	180	22	second	second	ADJ
dti-1334	180	23	,	,	PUNCT
dti-1334	180	24	biological	biological	ADJ
dti-1334	180	25	macromolecules	macromolecule	NOUN
dti-1334	180	26	are	be	AUX
dti-1334	180	27	not	not	PART
dti-1334	180	28	damaged	damage	VERB
dti-1334	180	29	(	(	PUNCT
dti-1334	180	30	bonner	bonner	PROPN
dti-1334	180	31	et	et	PROPN
dti-1334	180	32	al	al	PROPN
dti-1334	180	33	.	.	PROPN
dti-1334	180	34	1997	1997	NUM
dti-1334	180	35	;	;	PUNCT
dti-1334	180	36	emmert	emmert	NOUN
dti-1334	180	37	-	-	PUNCT
dti-1334	180	38	buck	buck	PROPN
dti-1334	180	39	et	et	PROPN
dti-1334	180	40	al	al	PROPN
dti-1334	180	41	.	.	PROPN
dti-1334	180	42	1996	1996	NUM
dti-1334	180	43	)	)	PUNCT
dti-1334	180	44	.	.	PUNCT
dti-1334	181	1	lcm	lcm	NOUN
dti-1334	181	2	is	be	AUX
dti-1334	181	3	compatible	compatible	ADJ
dti-1334	181	4	with	with	ADP
dti-1334	181	5	many	many	ADJ
dti-1334	181	6	common	common	ADJ
dti-1334	181	7	methods	method	NOUN
dti-1334	181	8	for	for	ADP
dti-1334	181	9	the	the	DET
dti-1334	181	10	preparation	preparation	NOUN
dti-1334	181	11	of	of	ADP
dti-1334	181	12	tissue	tissue	NOUN
dti-1334	181	13	sections	section	NOUN
dti-1334	181	14	.	.	PUNCT
dti-1334	182	1	tissues	tissue	NOUN
dti-1334	182	2	are	be	AUX
dti-1334	182	3	typically	typically	ADV
dti-1334	182	4	fi	fi	NOUN
dti-1334	183	1	xed	xe	VERB
dti-1334	184	1	by	by	ADP
dti-1334	184	2	alcohol	alcohol	NOUN
dti-1334	184	3	-	-	PUNCT
dti-1334	184	4	based	base	VERB
dti-1334	184	5	precipitation	precipitation	NOUN
dti-1334	184	6	techniques	technique	NOUN
dti-1334	185	1	.	.	PUNCT
dti-1334	186	1	although	although	SCONJ
dti-1334	186	2	aldehyde	aldehyde	NOUN
dti-1334	186	3	-	-	PUNCT
dti-1334	186	4	based	base	VERB
dti-1334	186	5	fi	fi	NOUN
dti-1334	186	6	xation	xation	NOUN
dti-1334	186	7	may	may	AUX
dti-1334	186	8	also	also	ADV
dti-1334	186	9	be	be	AUX
dti-1334	186	10	used	use	VERB
dti-1334	186	11	,	,	PUNCT
dti-1334	186	12	covalent	covalent	NOUN
dti-1334	186	13	cross	cross	NOUN
dti-1334	186	14	-	-	ADJ
dti-1334	186	15	linking	linking	NOUN
dti-1334	186	16	of	of	ADP
dti-1334	186	17	macromolecules	macromolecule	NOUN
dti-1334	186	18	can	can	AUX
dti-1334	186	19	potentially	potentially	ADV
dti-1334	186	20	interfere	interfere	VERB
dti-1334	186	21	with	with	ADP
dti-1334	186	22	subsequent	subsequent	ADJ
dti-1334	186	23	analysis	analysis	NOUN
dti-1334	186	24	of	of	ADP
dti-1334	186	25	proteins	protein	NOUN
dti-1334	186	26	.	.	PUNCT
dti-1334	187	1	tissue	tissue	NOUN
dti-1334	187	2	sections	section	NOUN
dti-1334	187	3	are	be	AUX
dti-1334	187	4	stained	stain	VERB
dti-1334	187	5	prior	prior	ADV
dti-1334	187	6	to	to	ADP
dti-1334	187	7	lcm	lcm	NOUN
dti-1334	187	8	procedures	procedure	NOUN
dti-1334	187	9	by	by	ADP
dti-1334	187	10	standard	standard	ADJ
dti-1334	187	11	methods	method	NOUN
dti-1334	187	12	such	such	ADJ
dti-1334	187	13	as	as	ADP
dti-1334	187	14	hematoxylin	hematoxylin	NOUN
dti-1334	187	15	and	and	CCONJ
dti-1334	187	16	eosin	eosin	NOUN
dti-1334	187	17	,	,	PUNCT
dti-1334	187	18	methylene	methylene	NOUN
dti-1334	187	19	green	green	ADJ
dti-1334	187	20	nuclear	nuclear	ADJ
dti-1334	187	21	stain	stain	NOUN
dti-1334	187	22	,	,	PUNCT
dti-1334	187	23	fl	fl	PRON
dti-1334	187	24	uorescence	uorescence	NOUN
dti-1334	187	25	in	in	ADP
dti-1334	187	26	situ	situ	ADJ
dti-1334	187	27	hybridization	hybridization	NOUN
dti-1334	187	28	,	,	PUNCT
dti-1334	187	29	or	or	CCONJ
dti-1334	187	30	immunohistochemistry	immunohistochemistry	NOUN
dti-1334	187	31	for	for	ADP
dti-1334	187	32	identifi	identifi	PROPN
dti-1334	187	33	cation	cation	NOUN
dti-1334	187	34	of	of	ADP
dti-1334	187	35	tissue	tissue	NOUN
dti-1334	187	36	morphology	morphology	NOUN
dti-1334	187	37	and	and	CCONJ
dti-1334	187	38	cell	cell	NOUN
dti-1334	187	39	populations	population	NOUN
dti-1334	187	40	of	of	ADP
dti-1334	187	41	interest	interest	NOUN
dti-1334	187	42	.	.	PUNCT
dti-1334	188	1	capture	capture	NOUN
dti-1334	188	2	of	of	ADP
dti-1334	188	3	approximately	approximately	ADV
dti-1334	188	4	50,000	50,000	NUM
dti-1334	188	5	cells	cell	NOUN
dti-1334	188	6	is	be	AUX
dti-1334	188	7	suffi	suffi	NOUN
dti-1334	188	8	cient	cient	NOUN
dti-1334	188	9	for	for	ADP
dti-1334	188	10	2	2	NUM
dti-1334	188	11	-	-	PUNCT
dti-1334	188	12	d	d	NOUN
dti-1334	188	13	page	page	NOUN
dti-1334	188	14	separation	separation	NOUN
dti-1334	188	15	and	and	CCONJ
dti-1334	188	16	visualization	visualization	NOUN
dti-1334	188	17	of	of	ADP
dti-1334	188	18	several	several	ADJ
dti-1334	188	19	hundred	hundred	NUM
dti-1334	188	20	distinct	distinct	ADJ
dti-1334	188	21	spots	spot	NOUN
dti-1334	188	22	using	use	VERB
dti-1334	188	23	silver	silver	NOUN
dti-1334	188	24	or	or	CCONJ
dti-1334	188	25	fl	fl	NUM
dti-1334	188	26	uorescent	uorescent	ADJ
dti-1334	188	27	stains	stain	NOUN
dti-1334	188	28	.	.	PUNCT
dti-1334	189	1	image	image	NOUN
dti-1334	189	2	analysis	analysis	NOUN
dti-1334	189	3	can	can	AUX
dti-1334	189	4	then	then	ADV
dti-1334	189	5	be	be	AUX
dti-1334	189	6	used	use	VERB
dti-1334	189	7	to	to	PART
dti-1334	189	8	identify	identify	VERB
dti-1334	189	9	differentially	differentially	ADV
dti-1334	189	10	expressed	express	VERB
dti-1334	189	11	proteins	protein	NOUN
dti-1334	189	12	.	.	PUNCT
dti-1334	190	1	62	62	NUM
dti-1334	190	2	shen	shen	NOUN
dti-1334	190	3	et	et	PROPN
dti-1334	190	4	al	al	PROPN
dti-1334	190	5	drug	drug	PROPN
dti-1334	190	6	target	target	NOUN
dti-1334	190	7	insights	insight	NOUN
dti-1334	190	8	2008:3	2008:3	NUM
dti-1334	190	9	the	the	DET
dti-1334	190	10	major	major	ADJ
dti-1334	190	11	challenge	challenge	NOUN
dti-1334	190	12	in	in	ADP
dti-1334	190	13	using	use	VERB
dti-1334	190	14	lcm	lcm	NOUN
dti-1334	190	15	for	for	ADP
dti-1334	190	16	proteomic	proteomic	ADJ
dti-1334	190	17	studies	study	NOUN
dti-1334	190	18	is	be	AUX
dti-1334	190	19	the	the	DET
dti-1334	190	20	limited	limited	ADJ
dti-1334	190	21	amounts	amount	NOUN
dti-1334	190	22	of	of	ADP
dti-1334	190	23	material	material	NOUN
dti-1334	190	24	collected	collect	VERB
dti-1334	190	25	.	.	PUNCT
dti-1334	191	1	for	for	ADP
dti-1334	191	2	most	most	ADJ
dti-1334	191	3	proteomic	proteomic	ADJ
dti-1334	191	4	applications	application	NOUN
dti-1334	191	5	,	,	PUNCT
dti-1334	191	6	it	it	PRON
dti-1334	191	7	is	be	AUX
dti-1334	191	8	necessary	necessary	ADJ
dti-1334	191	9	to	to	PART
dti-1334	191	10	procure	procure	VERB
dti-1334	191	11	dozens	dozen	NOUN
dti-1334	191	12	of	of	ADP
dti-1334	191	13	slides	slide	NOUN
dti-1334	191	14	to	to	PART
dti-1334	191	15	get	get	VERB
dti-1334	191	16	enough	enough	ADJ
dti-1334	191	17	material	material	NOUN
dti-1334	191	18	for	for	ADP
dti-1334	191	19	a	a	DET
dti-1334	191	20	single	single	ADJ
dti-1334	191	21	experiment	experiment	NOUN
dti-1334	191	22	.	.	PUNCT
dti-1334	192	1	although	although	SCONJ
dti-1334	192	2	this	this	DET
dti-1334	192	3	technique	technique	NOUN
dti-1334	192	4	is	be	AUX
dti-1334	192	5	faster	fast	ADJ
dti-1334	192	6	compthan	compthan	PROPN
dti-1334	192	7	the	the	DET
dti-1334	192	8	previously	previously	ADV
dti-1334	192	9	usedmicrodissection	usedmicrodissection	ADJ
dti-1334	192	10	methods	method	NOUN
dti-1334	192	11	,	,	PUNCT
dti-1334	192	12	isolation	isolation	NOUN
dti-1334	192	13	of	of	ADP
dti-1334	192	14	large	large	ADJ
dti-1334	192	15	numbers	number	NOUN
dti-1334	192	16	of	of	ADP
dti-1334	192	17	cells	cell	NOUN
dti-1334	192	18	from	from	ADP
dti-1334	192	19	many	many	ADJ
dti-1334	192	20	sections	section	NOUN
dti-1334	192	21	can	can	AUX
dti-1334	192	22	require	require	VERB
dti-1334	192	23	considerable	considerable	ADJ
dti-1334	192	24	time	time	NOUN
dti-1334	192	25	(	(	PUNCT
dti-1334	192	26	vogel	vogel	NOUN
dti-1334	192	27	et	et	PROPN
dti-1334	192	28	al	al	PROPN
dti-1334	192	29	.	.	PROPN
dti-1334	192	30	2007	2007	NUM
dti-1334	192	31	;	;	PUNCT
dti-1334	192	32	von	von	PROPN
dti-1334	192	33	eggeling	eggele	VERB
dti-1334	192	34	et	et	PROPN
dti-1334	192	35	al	al	PROPN
dti-1334	192	36	.	.	PROPN
dti-1334	192	37	2007	2007	NUM
dti-1334	192	38	)	)	PUNCT
dti-1334	192	39	.	.	PUNCT
dti-1334	193	1	this	this	DET
dti-1334	193	2	shortcoming	shortcoming	NOUN
dti-1334	193	3	also	also	ADV
dti-1334	193	4	signifi	signifi	VERB
dti-1334	193	5	cantly	cantly	ADV
dti-1334	193	6	limits	limit	VERB
dti-1334	193	7	one	one	NOUN
dti-1334	193	8	’s	’s	PART
dti-1334	193	9	ability	ability	NOUN
dti-1334	193	10	to	to	PART
dti-1334	193	11	detect	detect	VERB
dti-1334	193	12	and	and	CCONJ
dti-1334	193	13	quantify	quantify	ADJ
dti-1334	193	14	proteins	protein	NOUN
dti-1334	193	15	that	that	PRON
dti-1334	193	16	are	be	AUX
dti-1334	193	17	present	present	ADJ
dti-1334	193	18	at	at	ADP
dti-1334	193	19	low	low	ADJ
dti-1334	193	20	levels	level	NOUN
dti-1334	193	21	,	,	PUNCT
dti-1334	193	22	such	such	ADJ
dti-1334	193	23	as	as	ADP
dti-1334	193	24	transcription	transcription	NOUN
dti-1334	193	25	factors	factor	NOUN
dti-1334	193	26	,	,	PUNCT
dti-1334	193	27	signal	signal	ADJ
dti-1334	193	28	transduction	transduction	NOUN
dti-1334	193	29	molecules	molecule	NOUN
dti-1334	193	30	,	,	PUNCT
dti-1334	193	31	hormones	hormone	NOUN
dti-1334	193	32	,	,	PUNCT
dti-1334	193	33	etc	etc	X
dti-1334	193	34	.	.	X
dti-1334	193	35	,	,	PUNCT
dti-1334	193	36	even	even	ADV
dti-1334	193	37	when	when	SCONJ
dti-1334	193	38	highly	highly	ADV
dti-1334	193	39	sensitive	sensitive	ADJ
dti-1334	193	40	protein	protein	NOUN
dti-1334	193	41	analysis	analysis	NOUN
dti-1334	193	42	systems	system	NOUN
dti-1334	193	43	are	be	AUX
dti-1334	193	44	used	use	VERB
dti-1334	193	45	.	.	PUNCT
dti-1334	194	1	thus	thus	ADV
dti-1334	194	2	far	far	ADV
dti-1334	194	3	,	,	PUNCT
dti-1334	194	4	lcm	lcm	NOUN
dti-1334	194	5	has	have	AUX
dti-1334	194	6	been	be	AUX
dti-1334	194	7	used	use	VERB
dti-1334	194	8	more	more	ADV
dti-1334	194	9	successfully	successfully	ADV
dti-1334	194	10	with	with	ADP
dti-1334	194	11	nucleic	nucleic	ADJ
dti-1334	194	12	acids	acid	NOUN
dti-1334	194	13	(	(	PUNCT
dti-1334	194	14	dna	dna	NOUN
dti-1334	194	15	or	or	CCONJ
dti-1334	194	16	rna	rna	PROPN
dti-1334	194	17	)	)	PUNCT
dti-1334	194	18	,	,	PUNCT
dti-1334	194	19	for	for	ADP
dti-1334	194	20	which	which	PRON
dti-1334	194	21	amplifi	amplifi	NOUN
dti-1334	194	22	cation	cation	NOUN
dti-1334	194	23	methods	method	NOUN
dti-1334	194	24	are	be	AUX
dti-1334	194	25	available	available	ADJ
dti-1334	194	26	.	.	PUNCT
dti-1334	195	1	another	another	DET
dti-1334	195	2	disadvantage	disadvantage	NOUN
dti-1334	195	3	is	be	AUX
dti-1334	195	4	that	that	PRON
dti-1334	195	5	cover	cover	NOUN
dti-1334	195	6	slips	slip	NOUN
dti-1334	195	7	and	and	CCONJ
dti-1334	195	8	mounting	mount	VERB
dti-1334	195	9	solutions	solution	NOUN
dti-1334	195	10	are	be	AUX
dti-1334	195	11	not	not	PART
dti-1334	195	12	compatible	compatible	ADJ
dti-1334	195	13	with	with	ADP
dti-1334	195	14	lcm	lcm	NOUN
dti-1334	195	15	and	and	CCONJ
dti-1334	195	16	,	,	PUNCT
dti-1334	195	17	as	as	ADP
dti-1334	195	18	with	with	ADP
dti-1334	195	19	other	other	ADJ
dti-1334	195	20	microdissection	microdissection	NOUN
dti-1334	195	21	techniques	technique	NOUN
dti-1334	195	22	,	,	PUNCT
dti-1334	195	23	visualization	visualization	NOUN
dti-1334	195	24	of	of	ADP
dti-1334	195	25	samples	sample	NOUN
dti-1334	195	26	can	can	AUX
dti-1334	195	27	be	be	AUX
dti-1334	195	28	diffi	diffi	ADJ
dti-1334	195	29	cult	cult	NOUN
dti-1334	195	30	(	(	PUNCT
dti-1334	195	31	maitra	maitra	PROPN
dti-1334	195	32	et	et	PROPN
dti-1334	195	33	al	al	PROPN
dti-1334	195	34	.	.	PROPN
dti-1334	195	35	2001	2001	NUM
dti-1334	195	36	)	)	PUNCT
dti-1334	195	37	.	.	PUNCT
dti-1334	196	1	the	the	DET
dti-1334	196	2	newer	new	ADJ
dti-1334	196	3	versions	version	NOUN
dti-1334	196	4	of	of	ADP
dti-1334	196	5	the	the	DET
dti-1334	196	6	lcm	lcm	NOUN
dti-1334	196	7	have	have	VERB
dti-1334	196	8	a	a	DET
dti-1334	196	9	built	build	VERB
dti-1334	196	10	-	-	PUNCT
dti-1334	196	11	in	in	ADP
dti-1334	196	12	optical	optical	ADJ
dti-1334	196	13	system	system	NOUN
dti-1334	196	14	allowing	allow	VERB
dti-1334	196	15	the	the	DET
dti-1334	196	16	operator	operator	NOUN
dti-1334	196	17	to	to	PART
dti-1334	196	18	confi	confi	VERB
dti-1334	196	19	rm	rm	PROPN
dti-1334	196	20	the	the	DET
dti-1334	196	21	histology	histology	NOUN
dti-1334	196	22	of	of	ADP
dti-1334	196	23	the	the	DET
dti-1334	196	24	area	area	NOUN
dti-1334	196	25	to	to	PART
dti-1334	196	26	be	be	AUX
dti-1334	196	27	microdissected	microdissecte	VERB
dti-1334	196	28	without	without	ADP
dti-1334	196	29	transferring	transfer	VERB
dti-1334	196	30	the	the	DET
dti-1334	196	31	slide	slide	NOUN
dti-1334	196	32	.	.	PUNCT
dti-1334	197	1	for	for	ADP
dti-1334	197	2	an	an	DET
dti-1334	197	3	experienced	experienced	ADJ
dti-1334	197	4	histopathologist	histopathologist	NOUN
dti-1334	197	5	,	,	PUNCT
dti-1334	197	6	this	this	DET
dti-1334	197	7	suboptimal	suboptimal	ADJ
dti-1334	197	8	visualization	visualization	NOUN
dti-1334	197	9	should	should	AUX
dti-1334	197	10	not	not	PART
dti-1334	197	11	be	be	AUX
dti-1334	197	12	a	a	DET
dti-1334	197	13	problem	problem	NOUN
dti-1334	197	14	.	.	PUNCT
dti-1334	198	1	another	another	DET
dti-1334	198	2	limitation	limitation	NOUN
dti-1334	198	3	of	of	ADP
dti-1334	198	4	lcm	lcm	NOUN
dti-1334	198	5	is	be	AUX
dti-1334	198	6	that	that	SCONJ
dti-1334	198	7	it	it	PRON
dti-1334	198	8	is	be	AUX
dti-1334	198	9	not	not	PART
dti-1334	198	10	compatible	compatible	ADJ
dti-1334	198	11	with	with	ADP
dti-1334	198	12	live	live	ADJ
dti-1334	198	13	-	-	PUNCT
dti-1334	198	14	cell	cell	NOUN
dti-1334	198	15	analysis	analysis	NOUN
dti-1334	198	16	,	,	PUNCT
dti-1334	198	17	but	but	CCONJ
dti-1334	198	18	for	for	ADP
dti-1334	198	19	these	these	DET
dti-1334	198	20	applications	application	NOUN
dti-1334	198	21	fl	fl	INTJ
dti-1334	198	22	ow	ow	INTJ
dti-1334	198	23	cytometry	cytometry	PROPN
dti-1334	198	24	have	have	AUX
dti-1334	198	25	been	be	AUX
dti-1334	198	26	used	use	VERB
dti-1334	198	27	routinely	routinely	ADV
dti-1334	198	28	.	.	PUNCT
dti-1334	199	1	bioinformatic	bioinformatic	ADJ
dti-1334	199	2	analysis	analysis	NOUN
dti-1334	199	3	of	of	ADP
dti-1334	199	4	proteomics	proteomic	NOUN
dti-1334	199	5	data	datum	NOUN
dti-1334	199	6	technological	technological	ADJ
dti-1334	199	7	advances	advance	NOUN
dti-1334	199	8	highlighted	highlight	VERB
dti-1334	199	9	above	above	ADV
dti-1334	199	10	have	have	AUX
dti-1334	199	11	created	create	VERB
dti-1334	199	12	a	a	DET
dti-1334	199	13	bottleneck	bottleneck	NOUN
dti-1334	199	14	at	at	ADP
dti-1334	199	15	the	the	DET
dti-1334	199	16	level	level	NOUN
dti-1334	199	17	of	of	ADP
dti-1334	199	18	data	datum	NOUN
dti-1334	199	19	analysis	analysis	NOUN
dti-1334	199	20	and	and	CCONJ
dti-1334	199	21	resulted	result	VERB
dti-1334	199	22	in	in	ADP
dti-1334	199	23	an	an	DET
dti-1334	199	24	accumulation	accumulation	NOUN
dti-1334	199	25	of	of	ADP
dti-1334	199	26	experimental	experimental	ADJ
dti-1334	199	27	data	datum	NOUN
dti-1334	199	28	at	at	ADP
dti-1334	199	29	a	a	DET
dti-1334	199	30	rate	rate	NOUN
dti-1334	199	31	far	far	ADV
dti-1334	199	32	exceeding	exceed	VERB
dti-1334	199	33	the	the	DET
dti-1334	199	34	current	current	ADJ
dti-1334	199	35	ability	ability	NOUN
dti-1334	199	36	to	to	PART
dti-1334	199	37	assimilate	assimilate	VERB
dti-1334	199	38	that	that	DET
dti-1334	199	39	data	datum	NOUN
dti-1334	199	40	.	.	PUNCT
dti-1334	200	1	transforming	transform	VERB
dti-1334	200	2	the	the	DET
dti-1334	200	3	rapidly	rapidly	ADV
dti-1334	200	4	proliferating	proliferate	VERB
dti-1334	200	5	quantities	quantity	NOUN
dti-1334	200	6	of	of	ADP
dti-1334	200	7	experimental	experimental	ADJ
dti-1334	200	8	data	datum	NOUN
dti-1334	200	9	into	into	ADP
dti-1334	200	10	a	a	DET
dti-1334	200	11	usable	usable	ADJ
dti-1334	200	12	form	form	NOUN
dti-1334	200	13	in	in	ADP
dti-1334	200	14	order	order	NOUN
dti-1334	200	15	to	to	PART
dti-1334	200	16	facilitate	facilitate	VERB
dti-1334	200	17	data	datum	NOUN
dti-1334	200	18	analysis	analysis	NOUN
dti-1334	200	19	is	be	AUX
dti-1334	200	20	a	a	DET
dti-1334	200	21	challenging	challenging	ADJ
dti-1334	200	22	task	task	NOUN
dti-1334	200	23	(	(	PUNCT
dti-1334	200	24	meunier	meunier	NOUN
dti-1334	200	25	et	et	PROPN
dti-1334	200	26	al	al	PROPN
dti-1334	200	27	.	.	PROPN
dti-1334	200	28	2007	2007	NUM
dti-1334	200	29	)	)	PUNCT
dti-1334	200	30	.	.	PUNCT
dti-1334	201	1	although	although	SCONJ
dti-1334	201	2	interpretation	interpretation	NOUN
dti-1334	201	3	of	of	ADP
dti-1334	201	4	experimental	experimental	ADJ
dti-1334	201	5	datasets	dataset	NOUN
dti-1334	201	6	in	in	ADP
dti-1334	201	7	an	an	DET
dti-1334	201	8	interactive	interactive	ADJ
dti-1334	201	9	and	and	CCONJ
dti-1334	201	10	intuitive	intuitive	ADJ
dti-1334	201	11	way	way	NOUN
dti-1334	201	12	will	will	AUX
dti-1334	201	13	remain	remain	VERB
dti-1334	201	14	a	a	DET
dti-1334	201	15	big	big	ADJ
dti-1334	201	16	challenge	challenge	NOUN
dti-1334	201	17	in	in	ADP
dti-1334	201	18	the	the	DET
dti-1334	201	19	foreseeable	foreseeable	ADJ
dti-1334	201	20	future	future	NOUN
dti-1334	201	21	,	,	PUNCT
dti-1334	201	22	numerous	numerous	ADJ
dti-1334	201	23	specialized	specialized	ADJ
dti-1334	201	24	databases	database	NOUN
dti-1334	201	25	and	and	CCONJ
dti-1334	201	26	graphical	graphical	ADJ
dti-1334	201	27	tools	tool	NOUN
dti-1334	201	28	are	be	AUX
dti-1334	201	29	beginning	begin	VERB
dti-1334	201	30	to	to	PART
dti-1334	201	31	make	make	VERB
dti-1334	201	32	signifi	signifi	NOUN
dti-1334	201	33	ca	can	AUX
dti-1334	201	34	nt	not	PART
dti-1334	201	35	contributions	contribution	NOUN
dti-1334	201	36	toward	toward	ADP
dti-1334	201	37	dissecting	dissect	VERB
dti-1334	201	38	protein	protein	NOUN
dti-1334	201	39	complex	complex	ADJ
dti-1334	201	40	structures	structure	NOUN
dti-1334	201	41	,	,	PUNCT
dti-1334	201	42	generating	generate	VERB
dti-1334	201	43	functional	functional	ADJ
dti-1334	201	44	data	datum	NOUN
dti-1334	201	45	organization	organization	NOUN
dti-1334	201	46	and	and	CCONJ
dti-1334	201	47	revealing	reveal	VERB
dti-1334	201	48	hierarchical	hierarchical	ADJ
dti-1334	201	49	relationships	relationship	NOUN
dti-1334	201	50	(	(	PUNCT
dti-1334	201	51	ashburner	ashburner	NOUN
dti-1334	201	52	et	et	PROPN
dti-1334	201	53	al	al	PROPN
dti-1334	201	54	.	.	PROPN
dti-1334	201	55	2000	2000	NUM
dti-1334	201	56	;	;	PUNCT
dti-1334	201	57	bader	bader	PROPN
dti-1334	201	58	et	et	PROPN
dti-1334	201	59	al	al	PROPN
dti-1334	201	60	.	.	PROPN
dti-1334	201	61	2001	2001	NUM
dti-1334	201	62	;	;	PUNCT
dti-1334	201	63	bohannon	bohannon	PROPN
dti-1334	201	64	,	,	PUNCT
dti-1334	201	65	2002	2002	NUM
dti-1334	201	66	;	;	PUNCT
dti-1334	201	67	demir	demir	PROPN
dti-1334	201	68	et	et	PROPN
dti-1334	201	69	al	al	PROPN
dti-1334	201	70	.	.	PROPN
dti-1334	201	71	2002	2002	NUM
dti-1334	201	72	;	;	PUNCT
dti-1334	201	73	duan	duan	PROPN
dti-1334	201	74	et	et	PROPN
dti-1334	201	75	al	al	PROPN
dti-1334	201	76	.	.	PROPN
dti-1334	201	77	2002	2002	NUM
dti-1334	201	78	;	;	PUNCT
dti-1334	201	79	karp	karp	PROPN
dti-1334	201	80	,	,	PUNCT
dti-1334	201	81	1998	1998	NUM
dti-1334	201	82	;	;	PUNCT
dti-1334	201	83	karp	karp	PROPN
dti-1334	201	84	,	,	PUNCT
dti-1334	201	85	2001	2001	NUM
dti-1334	201	86	;	;	PUNCT
dti-1334	201	87	ruths	ruth	NOUN
dti-1334	201	88	et	et	PROPN
dti-1334	201	89	al	al	PROPN
dti-1334	201	90	.	.	PROPN
dti-1334	201	91	2000	2000	NUM
dti-1334	201	92	;	;	PUNCT
dti-1334	201	93	salamonsen	salamonsen	VERB
dti-1334	201	94	et	et	PROPN
dti-1334	201	95	al	al	PROPN
dti-1334	201	96	.	.	PROPN
dti-1334	201	97	1999	1999	NUM
dti-1334	201	98	;	;	PUNCT
dti-1334	201	99	sirava	sirava	NOUN
dti-1334	201	100	et	et	PROPN
dti-1334	201	101	al	al	PROPN
dti-1334	201	102	.	.	PROPN
dti-1334	201	103	2002	2002	NUM
dti-1334	201	104	)	)	PUNCT
dti-1334	201	105	.	.	PUNCT
dti-1334	202	1	a	a	DET
dti-1334	202	2	detailed	detailed	ADJ
dti-1334	202	3	discussion	discussion	NOUN
dti-1334	202	4	of	of	ADP
dti-1334	202	5	these	these	DET
dti-1334	202	6	bioinformatics	bioinformatics	NOUN
dti-1334	202	7	tools	tool	NOUN
dti-1334	202	8	are	be	AUX
dti-1334	202	9	outside	outside	ADP
dti-1334	202	10	the	the	DET
dti-1334	202	11	scope	scope	NOUN
dti-1334	202	12	of	of	ADP
dti-1334	202	13	this	this	DET
dti-1334	202	14	review	review	NOUN
dti-1334	202	15	,	,	PUNCT
dti-1334	202	16	but	but	CCONJ
dti-1334	202	17	a	a	DET
dti-1334	202	18	number	number	NOUN
dti-1334	202	19	of	of	ADP
dti-1334	202	20	excellent	excellent	ADJ
dti-1334	202	21	reviews	review	NOUN
dti-1334	202	22	are	be	AUX
dti-1334	202	23	available	available	ADJ
dti-1334	202	24	to	to	ADP
dti-1334	202	25	interested	interested	ADJ
dti-1334	202	26	readers	reader	NOUN
dti-1334	202	27	(	(	PUNCT
dti-1334	202	28	cannataro	cannataro	NOUN
dti-1334	202	29	,	,	PUNCT
dti-1334	202	30	2008	2008	NUM
dti-1334	202	31	;	;	PUNCT
dti-1334	202	32	deutsch	deutsch	NOUN
dti-1334	202	33	et	et	PROPN
dti-1334	202	34	al	al	PROPN
dti-1334	202	35	.	.	PROPN
dti-1334	202	36	2008	2008	NUM
dti-1334	202	37	;	;	PUNCT
dti-1334	202	38	ferre	ferre	PROPN
dti-1334	202	39	,	,	PUNCT
dti-1334	202	40	2005	2005	NUM
dti-1334	202	41	;	;	PUNCT
dti-1334	202	42	palagi	palagi	PROPN
dti-1334	202	43	et	et	PROPN
dti-1334	202	44	al	al	PROPN
dti-1334	202	45	.	.	PROPN
dti-1334	202	46	2006	2006	NUM
dti-1334	202	47	)	)	PUNCT
dti-1334	202	48	.	.	PUNCT
dti-1334	203	1	discussion	discussion	NOUN
dti-1334	203	2	proteins	protein	NOUN
dti-1334	203	3	are	be	AUX
dti-1334	203	4	the	the	DET
dti-1334	203	5	direct	direct	ADJ
dti-1334	203	6	effectors	effector	NOUN
dti-1334	203	7	of	of	ADP
dti-1334	203	8	cellular	cellular	ADJ
dti-1334	203	9	behavior	behavior	NOUN
dti-1334	203	10	rather	rather	ADV
dti-1334	203	11	than	than	ADP
dti-1334	203	12	their	their	PRON
dti-1334	203	13	dna	dna	NOUN
dti-1334	203	14	and	and	CCONJ
dti-1334	203	15	mrna	mrna	PROPN
dti-1334	203	16	templates	template	NOUN
dti-1334	203	17	.	.	PUNCT
dti-1334	204	1	characterization	characterization	NOUN
dti-1334	204	2	of	of	ADP
dti-1334	204	3	protein	protein	NOUN
dti-1334	204	4	expression	expression	NOUN
dti-1334	204	5	provides	provide	VERB
dti-1334	204	6	the	the	DET
dti-1334	204	7	most	most	ADV
dti-1334	204	8	immediate	immediate	ADJ
dti-1334	204	9	assessment	assessment	NOUN
dti-1334	204	10	of	of	ADP
dti-1334	204	11	cellular	cellular	ADJ
dti-1334	204	12	functional	functional	ADJ
dti-1334	204	13	capacity	capacity	NOUN
dti-1334	204	14	.	.	PUNCT
dti-1334	205	1	the	the	DET
dti-1334	205	2	use	use	NOUN
dti-1334	205	3	of	of	ADP
dti-1334	205	4	laser	laser	NOUN
dti-1334	205	5	capture	capture	NOUN
dti-1334	205	6	microdissection	microdissection	NOUN
dti-1334	205	7	(	(	PUNCT
dti-1334	205	8	lcm	lcm	NOUN
dti-1334	205	9	)	)	PUNCT
dti-1334	205	10	to	to	PART
dti-1334	205	11	maximize	maximize	VERB
dti-1334	205	12	the	the	DET
dti-1334	205	13	concentration	concentration	NOUN
dti-1334	205	14	of	of	ADP
dti-1334	205	15	cell	cell	NOUN
dti-1334	205	16	populations	population	NOUN
dti-1334	205	17	of	of	ADP
dti-1334	205	18	interest	interest	NOUN
dti-1334	205	19	within	within	ADP
dti-1334	205	20	the	the	DET
dti-1334	205	21	context	context	NOUN
dti-1334	205	22	of	of	ADP
dti-1334	205	23	their	their	PRON
dti-1334	205	24	microenvironment	microenvironment	NOUN
dti-1334	205	25	so	so	SCONJ
dti-1334	205	26	as	as	SCONJ
dti-1334	205	27	to	to	PART
dti-1334	205	28	optimize	optimize	VERB
dti-1334	205	29	protein	protein	NOUN
dti-1334	205	30	signal	signal	NOUN
dti-1334	205	31	detection	detection	NOUN
dti-1334	205	32	is	be	AUX
dti-1334	205	33	critical	critical	ADJ
dti-1334	205	34	for	for	ADP
dti-1334	205	35	quantitative	quantitative	ADJ
dti-1334	205	36	and	and	CCONJ
dti-1334	205	37	comparative	comparative	ADJ
dti-1334	205	38	analysis	analysis	NOUN
dti-1334	205	39	to	to	ADP
dti-1334	205	40	non	non	PRON
dti-1334	205	41	malignant	malignant	ADJ
dti-1334	205	42	expression	expression	NOUN
dti-1334	205	43	patterns	pattern	NOUN
dti-1334	205	44	.	.	PUNCT
dti-1334	206	1	use	use	NOUN
dti-1334	206	2	of	of	ADP
dti-1334	206	3	isobaric	isobaric	ADJ
dti-1334	206	4	tags	tag	NOUN
dti-1334	206	5	for	for	ADP
dti-1334	206	6	relative	relative	ADJ
dti-1334	206	7	and	and	CCONJ
dti-1334	206	8	absolute	absolute	ADJ
dti-1334	206	9	quantifi	quantifi	ADJ
dti-1334	206	10	cation	cation	NOUN
dti-1334	206	11	and	and	CCONJ
dti-1334	206	12	liquid	liquid	ADJ
dti-1334	206	13	chromatography	chromatography	NOUN
dti-1334	206	14	may	may	AUX
dti-1334	206	15	provide	provide	VERB
dti-1334	206	16	the	the	DET
dti-1334	206	17	broadest	broad	ADJ
dti-1334	206	18	quantitative	quantitative	ADJ
dti-1334	206	19	protein	protein	NOUN
dti-1334	206	20	analysis	analysis	NOUN
dti-1334	206	21	achievable	achievable	ADJ
dti-1334	206	22	for	for	ADP
dti-1334	206	23	unknown	unknown	ADJ
dti-1334	206	24	protein	protein	NOUN
dti-1334	206	25	comparison	comparison	NOUN
dti-1334	206	26	with	with	ADP
dti-1334	206	27	today	today	NOUN
dti-1334	206	28	’s	’s	PART
dti-1334	206	29	technology	technology	NOUN
dti-1334	206	30	.	.	PUNCT
dti-1334	207	1	proteins	protein	NOUN
dti-1334	207	2	assemble	assemble	VERB
dti-1334	207	3	themselves	themselves	PRON
dti-1334	207	4	into	into	ADP
dti-1334	207	5	networks	network	NOUN
dti-1334	207	6	through	through	ADP
dti-1334	207	7	a	a	DET
dti-1334	207	8	variety	variety	NOUN
dti-1334	207	9	of	of	ADP
dti-1334	207	10	protein	protein	NOUN
dti-1334	207	11	-	-	PUNCT
dti-1334	207	12	protein	protein	NOUN
dti-1334	207	13	interactions	interaction	NOUN
dti-1334	207	14	(	(	PUNCT
dti-1334	207	15	jensen	jensen	PROPN
dti-1334	207	16	,	,	PUNCT
dti-1334	207	17	2006	2006	NUM
dti-1334	207	18	)	)	PUNCT
dti-1334	207	19	.	.	PUNCT
dti-1334	208	1	the	the	DET
dti-1334	208	2	resolution	resolution	NOUN
dti-1334	208	3	of	of	ADP
dti-1334	208	4	these	these	DET
dti-1334	208	5	coupling	coupling	NOUN
dti-1334	208	6	events	event	NOUN
dti-1334	208	7	and	and	CCONJ
dti-1334	208	8	in	in	ADP
dti-1334	208	9	silico	silico	NOUN
dti-1334	208	10	prediction	prediction	NOUN
dti-1334	208	11	of	of	ADP
dti-1334	208	12	outcome	outcome	NOUN
dti-1334	208	13	from	from	ADP
dti-1334	208	14	the	the	DET
dti-1334	208	15	disruption	disruption	NOUN
dti-1334	208	16	of	of	ADP
dti-1334	208	17	these	these	DET
dti-1334	208	18	events	event	NOUN
dti-1334	208	19	are	be	AUX
dti-1334	208	20	likely	likely	ADJ
dti-1334	208	21	to	to	PART
dti-1334	208	22	provide	provide	VERB
dti-1334	208	23	the	the	DET
dti-1334	208	24	functional	functional	ADJ
dti-1334	208	25	basis	basis	NOUN
dti-1334	208	26	for	for	ADP
dti-1334	208	27	defi	defi	NOUN
dti-1334	208	28	ning	ning	NOUN
dti-1334	208	29	novel	novel	NOUN
dti-1334	208	30	and	and	CCONJ
dti-1334	208	31	,	,	PUNCT
dti-1334	208	32	potentially	potentially	ADV
dti-1334	208	33	,	,	PUNCT
dti-1334	208	34	effective	effective	ADJ
dti-1334	208	35	targets	target	NOUN
dti-1334	208	36	for	for	ADP
dti-1334	208	37	drug	drug	NOUN
dti-1334	208	38	therapy	therapy	NOUN
dti-1334	208	39	(	(	PUNCT
dti-1334	208	40	aksenov	aksenov	PROPN
dti-1334	208	41	et	et	PROPN
dti-1334	208	42	al	al	PROPN
dti-1334	208	43	.	.	PROPN
dti-1334	208	44	2005	2005	NUM
dti-1334	208	45	;	;	PUNCT
dti-1334	208	46	christopher	christopher	PROPN
dti-1334	208	47	et	et	PROPN
dti-1334	208	48	al	al	PROPN
dti-1334	208	49	.	.	PROPN
dti-1334	208	50	2004	2004	NUM
dti-1334	208	51	;	;	PUNCT
dti-1334	208	52	pearl	pearl	NOUN
dti-1334	208	53	,	,	PUNCT
dti-1334	208	54	2000	2000	NUM
dti-1334	208	55	;	;	PUNCT
dti-1334	208	56	senzer	senzer	NOUN
dti-1334	208	57	et	et	PROPN
dti-1334	208	58	al	al	PROPN
dti-1334	208	59	.	.	PROPN
dti-1334	208	60	2005	2005	NUM
dti-1334	208	61	)	)	PUNCT
dti-1334	208	62	.	.	PUNCT
dti-1334	209	1	pathogenic	pathogenic	ADJ
dti-1334	209	2	gene	gene	NOUN
dti-1334	209	3	mutations	mutation	NOUN
dti-1334	209	4	,	,	PUNCT
dti-1334	209	5	gene	gene	NOUN
dti-1334	209	6	loss	loss	NOUN
dti-1334	209	7	,	,	PUNCT
dti-1334	209	8	and	and	CCONJ
dti-1334	209	9	gene	gene	NOUN
dti-1334	209	10	duplication	duplication	NOUN
dti-1334	209	11	or	or	CCONJ
dti-1334	209	12	amplifi	amplifi	NOUN
dti-1334	209	13	cation	cation	NOUN
dti-1334	209	14	as	as	ADV
dti-1334	209	15	well	well	ADV
dti-1334	209	16	as	as	ADP
dti-1334	209	17	epigenetic	epigenetic	ADJ
dti-1334	209	18	modifi	modifi	NOUN
dti-1334	209	19	cations	cation	NOUN
dti-1334	209	20	can	can	AUX
dti-1334	209	21	result	result	VERB
dti-1334	209	22	in	in	ADP
dti-1334	209	23	defective	defective	ADJ
dti-1334	209	24	,	,	PUNCT
dti-1334	209	25	absent	absent	ADJ
dti-1334	209	26	or	or	CCONJ
dti-1334	209	27	overexpressed	overexpressed	ADJ
dti-1334	209	28	proteins	protein	NOUN
dti-1334	209	29	.	.	PUNCT
dti-1334	210	1	these	these	DET
dti-1334	210	2	proteins	protein	NOUN
dti-1334	210	3	realign	realign	VERB
dti-1334	210	4	within	within	ADP
dti-1334	210	5	the	the	DET
dti-1334	210	6	cellular	cellular	ADJ
dti-1334	210	7	protein	protein	NOUN
dti-1334	210	8	network	network	NOUN
dti-1334	210	9	in	in	ADP
dti-1334	210	10	a	a	DET
dti-1334	210	11	“	"	PUNCT
dti-1334	210	12	degenerative	degenerative	ADJ
dti-1334	210	13	”	"	PUNCT
dti-1334	210	14	pattern	pattern	NOUN
dti-1334	210	15	resulting	result	VERB
dti-1334	210	16	in	in	ADP
dti-1334	210	17	an	an	DET
dti-1334	210	18	oncopathologic	oncopathologic	ADJ
dti-1334	210	19	hostile	hostile	ADJ
dti-1334	210	20	takeover	takeover	NOUN
dti-1334	210	21	(	(	PUNCT
dti-1334	210	22	ajani	ajani	NOUN
dti-1334	210	23	and	and	CCONJ
dti-1334	210	24	allgood	allgood	NOUN
dti-1334	210	25	,	,	PUNCT
dti-1334	210	26	2005	2005	NUM
dti-1334	210	27	)	)	PUNCT
dti-1334	210	28	.	.	PUNCT
dti-1334	211	1	the	the	DET
dti-1334	211	2	culling	culling	NOUN
dti-1334	211	3	of	of	ADP
dti-1334	211	4	these	these	DET
dti-1334	211	5	unique	unique	ADJ
dti-1334	211	6	tumor	tumor	NOUN
dti-1334	211	7	proteomic	proteomic	NOUN
dti-1334	211	8	patterns	pattern	NOUN
dti-1334	211	9	provides	provide	VERB
dti-1334	211	10	the	the	DET
dti-1334	211	11	basis	basis	NOUN
dti-1334	211	12	for	for	ADP
dti-1334	211	13	a	a	DET
dti-1334	211	14	systematic	systematic	ADJ
dti-1334	211	15	approach	approach	NOUN
dti-1334	211	16	to	to	ADP
dti-1334	211	17	the	the	DET
dti-1334	211	18	development	development	NOUN
dti-1334	211	19	of	of	ADP
dti-1334	211	20	personalized	personalized	ADJ
dti-1334	211	21	cancer	cancer	NOUN
dti-1334	211	22	therapeutics	therapeutic	NOUN
dti-1334	211	23	,	,	PUNCT
dti-1334	211	24	especially	especially	ADV
dti-1334	211	25	when	when	SCONJ
dti-1334	211	26	coupled	couple	VERB
dti-1334	211	27	with	with	ADP
dti-1334	211	28	functional	functional	ADJ
dti-1334	211	29	analysis	analysis	NOUN
dti-1334	211	30	of	of	ADP
dti-1334	211	31	individual	individual	ADJ
dti-1334	211	32	candidate	candidate	NOUN
dti-1334	211	33	gene	gene	NOUN
dti-1334	211	34	/	/	SYM
dti-1334	211	35	protein	protein	NOUN
dti-1334	211	36	couplets	couplet	NOUN
dti-1334	211	37	.	.	PUNCT
dti-1334	212	1	correlation	correlation	NOUN
dti-1334	212	2	of	of	ADP
dti-1334	212	3	gene	gene	NOUN
dti-1334	212	4	expression	expression	NOUN
dti-1334	212	5	patterns	pattern	NOUN
dti-1334	212	6	(	(	PUNCT
dti-1334	212	7	protein	protein	NOUN
dti-1334	212	8	mediated	mediate	VERB
dti-1334	212	9	activity	activity	NOUN
dti-1334	212	10	)	)	PUNCT
dti-1334	212	11	with	with	ADP
dti-1334	212	12	disease	disease	NOUN
dti-1334	212	13	outcome	outcome	NOUN
dti-1334	212	14	(	(	PUNCT
dti-1334	212	15	survival	survival	NOUN
dti-1334	212	16	)	)	PUNCT
dti-1334	212	17	has	have	AUX
dti-1334	212	18	been	be	AUX
dti-1334	212	19	demonstrated	demonstrate	VERB
dti-1334	212	20	in	in	ADP
dti-1334	212	21	a	a	DET
dti-1334	212	22	variety	variety	NOUN
dti-1334	212	23	of	of	ADP
dti-1334	212	24	cancers	cancer	NOUN
dti-1334	212	25	(	(	PUNCT
dti-1334	212	26	bhattacharjee	bhattacharjee	PROPN
dti-1334	212	27	et	et	PROPN
dti-1334	212	28	al	al	PROPN
dti-1334	212	29	.	.	PROPN
dti-1334	212	30	2001	2001	NUM
dti-1334	212	31	;	;	PUNCT
dti-1334	212	32	garber	garber	PROPN
dti-1334	212	33	et	et	PROPN
dti-1334	212	34	al	al	PROPN
dti-1334	212	35	.	.	PROPN
dti-1334	212	36	2001	2001	NUM
dti-1334	212	37	;	;	PUNCT
dti-1334	212	38	perou	perou	PROPN
dti-1334	212	39	et	et	PROPN
dti-1334	212	40	al	al	PROPN
dti-1334	212	41	.	.	PROPN
dti-1334	212	42	2000	2000	NUM
dti-1334	212	43	;	;	PUNCT
dti-1334	212	44	rosenwald	rosenwald	NOUN
dti-1334	212	45	et	et	PROPN
dti-1334	212	46	al	al	PROPN
dti-1334	212	47	.	.	PROPN
dti-1334	212	48	2002	2002	NUM
dti-1334	212	49	;	;	PUNCT
dti-1334	212	50	rosenwald	rosenwald	NOUN
dti-1334	212	51	et	et	PROPN
dti-1334	212	52	al	al	PROPN
dti-1334	212	53	.	.	PROPN
dti-1334	212	54	2003	2003	NUM
dti-1334	212	55	;	;	PUNCT
dti-1334	212	56	shipp	shipp	VERB
dti-1334	212	57	et	et	PROPN
dti-1334	212	58	al	al	PROPN
dti-1334	212	59	.	.	PROPN
dti-1334	212	60	2002	2002	NUM
dti-1334	212	61	)	)	PUNCT
dti-1334	212	62	.	.	PUNCT
dti-1334	213	1	however	however	ADV
dti-1334	213	2	,	,	PUNCT
dti-1334	213	3	gene	gene	NOUN
dti-1334	213	4	transcript	transcript	NOUN
dti-1334	213	5	levels	level	NOUN
dti-1334	213	6	often	often	ADV
dti-1334	213	7	show	show	VERB
dti-1334	213	8	poor	poor	ADJ
dti-1334	213	9	correlation	correlation	NOUN
dti-1334	213	10	with	with	ADP
dti-1334	213	11	protein	protein	NOUN
dti-1334	213	12	levels	level	NOUN
dti-1334	213	13	and	and	CCONJ
dti-1334	213	14	they	they	PRON
dti-1334	213	15	can	can	AUX
dti-1334	213	16	not	not	PART
dti-1334	213	17	predict	predict	VERB
dti-1334	213	18	post	post	ADJ
dti-1334	213	19	translational	translational	ADJ
dti-1334	213	20	modifi	modifi	NOUN
dti-1334	213	21	cations	cation	NOUN
dti-1334	213	22	.	.	PUNCT
dti-1334	214	1	63	63	NUM
dti-1334	214	2	proteomics	proteomic	NOUN
dti-1334	214	3	in	in	ADP
dti-1334	214	4	personalized	personalized	ADJ
dti-1334	214	5	cancer	cancer	NOUN
dti-1334	214	6	therapy	therapy	NOUN
dti-1334	214	7	drug	drug	NOUN
dti-1334	214	8	target	target	NOUN
dti-1334	214	9	insights	insight	NOUN
dti-1334	214	10	2008:3	2008:3	NUM
dti-1334	214	11	by	by	ADP
dti-1334	214	12	using	use	VERB
dti-1334	214	13	the	the	DET
dti-1334	214	14	following	follow	VERB
dti-1334	214	15	criteria	criterion	NOUN
dti-1334	214	16	:	:	PUNCT
dti-1334	214	17	(	(	PUNCT
dti-1334	214	18	1	1	X
dti-1334	214	19	)	)	PUNCT
dti-1334	214	20	differential	differential	ADJ
dti-1334	214	21	expression	expression	NOUN
dti-1334	214	22	,	,	PUNCT
dti-1334	214	23	(	(	PUNCT
dti-1334	214	24	2	2	X
dti-1334	214	25	)	)	PUNCT
dti-1334	214	26	linkage	linkage	NOUN
dti-1334	214	27	to	to	ADP
dti-1334	214	28	essential	essential	ADJ
dti-1334	214	29	oncogenic	oncogenic	ADJ
dti-1334	214	30	processes	process	NOUN
dti-1334	214	31	,	,	PUNCT
dti-1334	214	32	(	(	PUNCT
dti-1334	214	33	3	3	X
dti-1334	214	34	)	)	PUNCT
dti-1334	214	35	high	high	ADJ
dti-1334	214	36	connectivity	connectivity	NOUN
dti-1334	214	37	,	,	PUNCT
dti-1334	214	38	and	and	CCONJ
dti-1334	214	39	(	(	PUNCT
dti-1334	214	40	4	4	X
dti-1334	214	41	)	)	PUNCT
dti-1334	214	42	high	high	ADJ
dti-1334	214	43	bottleneck	bottleneck	NOUN
dti-1334	214	44	centrality	centrality	NOUN
dti-1334	214	45	,	,	PUNCT
dti-1334	214	46	it	it	PRON
dti-1334	214	47	is	be	AUX
dti-1334	214	48	feasible	feasible	ADJ
dti-1334	214	49	to	to	PART
dti-1334	214	50	reduce	reduce	VERB
dti-1334	214	51	a	a	DET
dti-1334	214	52	fi	fi	NOUN
dti-1334	214	53	nite	nite	ADJ
dti-1334	214	54	number	number	NOUN
dti-1334	214	55	of	of	ADP
dti-1334	214	56	overexpressed	overexpressed	ADJ
dti-1334	214	57	proteins	protein	NOUN
dti-1334	214	58	in	in	ADP
dti-1334	214	59	malignant	malignant	ADJ
dti-1334	214	60	tissue	tissue	NOUN
dti-1334	214	61	into	into	ADP
dti-1334	214	62	a	a	DET
dti-1334	214	63	smaller	small	ADJ
dti-1334	214	64	subset	subset	NOUN
dti-1334	214	65	of	of	ADP
dti-1334	214	66	candidate	candidate	NOUN
dti-1334	214	67	targets	target	NOUN
dti-1334	214	68	,	,	PUNCT
dti-1334	214	69	against	against	ADP
dti-1334	214	70	which	which	PRON
dti-1334	214	71	potentially	potentially	ADV
dti-1334	214	72	therapeutic	therapeutic	ADJ
dti-1334	214	73	sirna	sirna	PROPN
dti-1334	214	74	or	or	CCONJ
dti-1334	214	75	shrna	shrna	NOUN
dti-1334	214	76	agents	agent	NOUN
dti-1334	214	77	can	can	AUX
dti-1334	214	78	be	be	AUX
dti-1334	214	79	constructed	construct	VERB
dti-1334	214	80	(	(	PUNCT
dti-1334	214	81	nemunaitis	nemunaitis	NOUN
dti-1334	214	82	et	et	PROPN
dti-1334	214	83	al	al	PROPN
dti-1334	214	84	.	.	PROPN
dti-1334	214	85	2007	2007	NUM
dti-1334	214	86	)	)	PUNCT
dti-1334	214	87	.	.	PUNCT
dti-1334	215	1	these	these	DET
dti-1334	215	2	products	product	NOUN
dti-1334	215	3	can	can	AUX
dti-1334	215	4	then	then	ADV
dti-1334	215	5	be	be	AUX
dti-1334	215	6	used	use	VERB
dti-1334	215	7	to	to	PART
dti-1334	215	8	enable	enable	VERB
dti-1334	215	9	a	a	DET
dti-1334	215	10	systematic	systematic	ADJ
dti-1334	215	11	loss	loss	NOUN
dti-1334	215	12	-	-	PUNCT
dti-1334	215	13	of	of	ADP
dti-1334	215	14	-	-	PUNCT
dti-1334	215	15	function	function	NOUN
dti-1334	215	16	analysis	analysis	NOUN
dti-1334	215	17	,	,	PUNCT
dti-1334	215	18	in	in	ADP
dti-1334	215	19	order	order	NOUN
dti-1334	215	20	to	to	PART
dti-1334	215	21	validate	validate	VERB
dti-1334	215	22	an	an	DET
dti-1334	215	23	integrated	integrate	VERB
dti-1334	215	24	and	and	CCONJ
dti-1334	215	25	coordinated	coordinated	ADJ
dti-1334	215	26	complex	complex	NOUN
dti-1334	215	27	of	of	ADP
dti-1334	215	28	biologically	biologically	ADV
dti-1334	215	29	relevant	relevant	ADJ
dti-1334	215	30	“	"	PUNCT
dti-1334	215	31	gene	gene	NOUN
dti-1334	215	32	targets	target	NOUN
dti-1334	215	33	”	"	PUNCT
dti-1334	215	34	for	for	ADP
dti-1334	215	35	trial	trial	NOUN
dti-1334	215	36	investigation	investigation	NOUN
dti-1334	215	37	.	.	PUNCT
dti-1334	216	1	it	it	PRON
dti-1334	216	2	is	be	AUX
dti-1334	216	3	envisioned	envision	VERB
dti-1334	216	4	that	that	SCONJ
dti-1334	216	5	future	future	PROPN
dti-1334	216	6	rnai	rnai	PROPN
dti-1334	216	7	based	base	VERB
dti-1334	216	8	gene	gene	NOUN
dti-1334	216	9	therapy	therapy	NOUN
dti-1334	216	10	(	(	PUNCT
dti-1334	216	11	one	one	NUM
dti-1334	216	12	possible	possible	ADJ
dti-1334	216	13	approach	approach	NOUN
dti-1334	216	14	)	)	PUNCT
dti-1334	216	15	for	for	ADP
dti-1334	216	16	cancer	cancer	NOUN
dti-1334	216	17	can	can	AUX
dti-1334	216	18	be	be	AUX
dti-1334	216	19	prescribed	prescribe	VERB
dti-1334	216	20	based	base	VERB
dti-1334	216	21	on	on	ADP
dti-1334	216	22	the	the	DET
dti-1334	216	23	integrated	integrate	VERB
dti-1334	216	24	mrna	mrna	PROPN
dti-1334	216	25	-	-	PUNCT
dti-1334	216	26	proteomic	proteomic	ADJ
dti-1334	216	27	co	co	NOUN
dti-1334	216	28	-	-	NOUN
dti-1334	216	29	expression	expression	ADJ
dti-1334	216	30	profi	profi	NOUN
dti-1334	216	31	le	le	PROPN
dti-1334	216	32	of	of	ADP
dti-1334	216	33	each	each	DET
dti-1334	216	34	individual	individual	NOUN
dti-1334	216	35	’s	’s	PART
dti-1334	216	36	tumor	tumor	NOUN
dti-1334	216	37	.	.	PUNCT
dti-1334	217	1	there	there	PRON
dti-1334	217	2	are	be	VERB
dti-1334	217	3	available	available	ADJ
dti-1334	217	4	data	datum	NOUN
dti-1334	217	5	allowing	allow	VERB
dti-1334	217	6	preliminary	preliminary	ADJ
dti-1334	217	7	assessment	assessment	NOUN
dti-1334	217	8	of	of	ADP
dti-1334	217	9	the	the	DET
dti-1334	217	10	potential	potential	ADJ
dti-1334	217	11	comparative	comparative	ADJ
dti-1334	217	12	therapeutic	therapeutic	ADJ
dti-1334	217	13	benefi	benefi	NOUN
dti-1334	217	14	ts	ts	ADP
dti-1334	217	15	of	of	ADP
dti-1334	217	16	sirna	sirna	PROPN
dti-1334	217	17	versus	versus	ADP
dti-1334	217	18	shrna	shrna	PROPN
dti-1334	217	19	as	as	ADP
dti-1334	217	20	rnai	rnai	NOUN
dti-1334	217	21	effectors	effector	NOUN
dti-1334	217	22	.	.	PUNCT
dti-1334	218	1	synthetic	synthetic	PROPN
dti-1334	218	2	sirna	sirna	PROPN
dti-1334	218	3	can	can	AUX
dti-1334	218	4	be	be	AUX
dti-1334	218	5	delivered	deliver	VERB
dti-1334	218	6	to	to	ADP
dti-1334	218	7	the	the	DET
dti-1334	218	8	cytosol	cytosol	NOUN
dti-1334	218	9	for	for	ADP
dti-1334	218	10	direct	direct	ADJ
dti-1334	218	11	incorporation	incorporation	NOUN
dti-1334	218	12	into	into	ADP
dti-1334	218	13	the	the	DET
dti-1334	218	14	rnainduced	rnainduced	ADJ
dti-1334	218	15	silencing	silence	VERB
dti-1334	218	16	complex	complex	ADJ
dti-1334	218	17	(	(	PUNCT
dti-1334	218	18	risc	risc	PROPN
dti-1334	218	19	)	)	PUNCT
dti-1334	218	20	,	,	PUNCT
dti-1334	218	21	whereas	whereas	SCONJ
dti-1334	218	22	shrna	shrna	NOUN
dti-1334	218	23	requires	require	VERB
dti-1334	218	24	dicer	dicer	NOUN
dti-1334	218	25	processing	processing	NOUN
dti-1334	218	26	or	or	CCONJ
dti-1334	218	27	,	,	PUNCT
dti-1334	218	28	if	if	SCONJ
dti-1334	218	29	delivered	deliver	VERB
dti-1334	218	30	in	in	ADP
dti-1334	218	31	a	a	DET
dti-1334	218	32	plasmid	plasmid	ADJ
dti-1334	218	33	,	,	PUNCT
dti-1334	218	34	nuclear	nuclear	ADJ
dti-1334	218	35	penetration	penetration	NOUN
dti-1334	218	36	and	and	CCONJ
dti-1334	218	37	translational	translational	ADJ
dti-1334	218	38	processing	processing	NOUN
dti-1334	218	39	to	to	PART
dti-1334	218	40	produce	produce	VERB
dti-1334	218	41	the	the	DET
dti-1334	218	42	hairpin	hairpin	NOUN
dti-1334	218	43	shrna	shrna	NOUN
dti-1334	218	44	for	for	ADP
dti-1334	218	45	dicer	dicer	NOUN
dti-1334	218	46	.	.	PUNCT
dti-1334	219	1	conversely	conversely	ADV
dti-1334	219	2	,	,	PUNCT
dti-1334	219	3	dicer	dicer	NOUN
dti-1334	219	4	processing	processing	NOUN
dti-1334	219	5	may	may	AUX
dti-1334	219	6	result	result	VERB
dti-1334	219	7	in	in	ADP
dti-1334	219	8	a	a	DET
dti-1334	219	9	more	more	ADV
dti-1334	219	10	potent	potent	ADJ
dti-1334	219	11	rnai	rnai	NOUN
dti-1334	219	12	effector	effector	NOUN
dti-1334	219	13	(	(	PUNCT
dti-1334	219	14	siolas	siolas	PROPN
dti-1334	219	15	et	et	PROPN
dti-1334	219	16	al	al	PROPN
dti-1334	219	17	.	.	PROPN
dti-1334	219	18	2005	2005	NUM
dti-1334	219	19	)	)	PUNCT
dti-1334	219	20	.	.	PUNCT
dti-1334	220	1	furthermore	furthermore	ADV
dti-1334	220	2	,	,	PUNCT
dti-1334	220	3	by	by	ADP
dti-1334	220	4	using	use	VERB
dti-1334	220	5	mir-30	mir-30	NUM
dti-1334	220	6	based	base	VERB
dti-1334	220	7	shrna	shrna	NOUN
dti-1334	220	8	,	,	PUNCT
dti-1334	220	9	pol	pol	PROPN
dti-1334	220	10	ii	ii	PROPN
dti-1334	220	11	promoters	promoter	NOUN
dti-1334	220	12	(	(	PUNCT
dti-1334	220	13	rather	rather	ADV
dti-1334	220	14	than	than	ADP
dti-1334	220	15	pol	pol	PROPN
dti-1334	220	16	iii	iii	PROPN
dti-1334	220	17	)	)	PUNCT
dti-1334	220	18	can	can	AUX
dti-1334	220	19	be	be	AUX
dti-1334	220	20	used	use	VERB
dti-1334	220	21	to	to	PART
dti-1334	220	22	drive	drive	VERB
dti-1334	220	23	shrna	shrna	ADJ
dti-1334	220	24	-	-	PUNCT
dti-1334	220	25	mir	mir	NOUN
dti-1334	220	26	expression	expression	NOUN
dti-1334	220	27	,	,	PUNCT
dti-1334	220	28	allow	allow	VERB
dti-1334	220	29	for	for	ADP
dti-1334	220	30	greater	great	ADJ
dti-1334	220	31	regulation	regulation	NOUN
dti-1334	220	32	and	and	CCONJ
dti-1334	220	33	,	,	PUNCT
dti-1334	220	34	perhaps	perhaps	ADV
dti-1334	220	35	,	,	PUNCT
dti-1334	220	36	minimize	minimize	VERB
dti-1334	220	37	the	the	DET
dti-1334	220	38	potential	potential	ADJ
dti-1334	220	39	risk	risk	NOUN
dti-1334	220	40	of	of	ADP
dti-1334	220	41	exportin-5	exportin-5	NUM
dti-1334	220	42	saturation	saturation	NOUN
dti-1334	220	43	(	(	PUNCT
dti-1334	220	44	dickins	dickin	NOUN
dti-1334	220	45	et	et	PROPN
dti-1334	220	46	al	al	PROPN
dti-1334	220	47	.	.	PROPN
dti-1334	220	48	2005	2005	NUM
dti-1334	220	49	)	)	PUNCT
dti-1334	220	50	.	.	PUNCT
dti-1334	221	1	obversely	obversely	ADV
dti-1334	221	2	,	,	PUNCT
dti-1334	221	3	sirna	sirna	PROPN
dti-1334	221	4	can	can	AUX
dti-1334	221	5	not	not	PART
dti-1334	221	6	be	be	AUX
dti-1334	221	7	amplifi	amplifi	NOUN
dti-1334	221	8	ed	ed	NOUN
dti-1334	221	9	intracellularly	intracellularly	ADV
dti-1334	221	10	as	as	SCONJ
dti-1334	221	11	can	can	AUX
dti-1334	221	12	plasmid	plasmid	NOUN
dti-1334	221	13	-	-	PUNCT
dti-1334	221	14	expressed	express	VERB
dti-1334	221	15	shrna	shrna	NOUN
dti-1334	221	16	.	.	PUNCT
dti-1334	222	1	preliminary	preliminary	ADJ
dti-1334	222	2	comparisons	comparison	NOUN
dti-1334	222	3	between	between	ADP
dti-1334	222	4	sirna	sirna	PROPN
dti-1334	222	5	and	and	CCONJ
dti-1334	222	6	shrna	shrna	PROPN
dti-1334	222	7	(	(	PUNCT
dti-1334	222	8	two	two	NUM
dti-1334	222	9	methods	method	NOUN
dti-1334	222	10	of	of	ADP
dti-1334	222	11	controlling	control	VERB
dti-1334	222	12	rna	rna	NOUN
dti-1334	222	13	expression	expression	NOUN
dti-1334	222	14	and	and	CCONJ
dti-1334	222	15	target	target	VERB
dti-1334	222	16	protein	protein	NOUN
dti-1334	222	17	expression	expression	NOUN
dti-1334	222	18	)	)	PUNCT
dti-1334	222	19	indicate	indicate	VERB
dti-1334	222	20	that	that	DET
dti-1334	222	21	shrna	shrna	ADJ
dti-1334	222	22	induced	induced	ADJ
dti-1334	222	23	knockdown	knockdown	NOUN
dti-1334	222	24	is	be	AUX
dti-1334	222	25	more	more	ADV
dti-1334	222	26	durable	durable	ADJ
dti-1334	222	27	and	and	CCONJ
dti-1334	222	28	effi	effi	PROPN
dti-1334	222	29	cient	cient	PROPN
dti-1334	222	30	than	than	ADP
dti-1334	222	31	sirna	sirna	PROPN
dti-1334	222	32	(	(	PUNCT
dti-1334	222	33	lage	lage	PROPN
dti-1334	222	34	,	,	PUNCT
dti-1334	222	35	2005	2005	NUM
dti-1334	222	36	;	;	PUNCT
dti-1334	222	37	mcanuff	mcanuff	NOUN
dti-1334	222	38	et	et	PROPN
dti-1334	222	39	al	al	PROPN
dti-1334	222	40	.	.	PROPN
dti-1334	222	41	2007	2007	NUM
dti-1334	222	42	;	;	PUNCT
dti-1334	222	43	stein	stein	PROPN
dti-1334	222	44	,	,	PUNCT
dti-1334	222	45	2006	2006	NUM
dti-1334	222	46	;	;	PUNCT
dti-1334	222	47	vlassov	vlassov	PROPN
dti-1334	222	48	et	et	PROPN
dti-1334	222	49	al	al	PROPN
dti-1334	222	50	.	.	PROPN
dti-1334	222	51	2007	2007	NUM
dti-1334	222	52	)	)	PUNCT
dti-1334	222	53	and	and	CCONJ
dti-1334	222	54	,	,	PUNCT
dti-1334	222	55	furthermore	furthermore	ADV
dti-1334	222	56	,	,	PUNCT
dti-1334	222	57	amenable	amenable	ADJ
dti-1334	222	58	to	to	ADP
dti-1334	222	59	second	second	ADJ
dti-1334	222	60	and	and	CCONJ
dti-1334	222	61	third	third	ADJ
dti-1334	222	62	layers	layer	NOUN
dti-1334	222	63	of	of	ADP
dti-1334	222	64	tumor	tumor	PROPN
dti-1334	222	65	specifi	specifi	PROPN
dti-1334	222	66	city	city	PROPN
dti-1334	222	67	via	via	ADP
dti-1334	222	68	tumor	tumor	NOUN
dti-1334	222	69	-	-	PUNCT
dti-1334	222	70	targeted	target	VERB
dti-1334	222	71	vector	vector	NOUN
dti-1334	222	72	delivery	delivery	NOUN
dti-1334	222	73	and	and	CCONJ
dti-1334	222	74	tumor	tumor	NOUN
dti-1334	222	75	specifi	specifi	PROPN
dti-1334	222	76	c	c	PROPN
dti-1334	222	77	promoter	promoter	NOUN
dti-1334	222	78	control	control	NOUN
dti-1334	222	79	thereby	thereby	ADV
dti-1334	222	80	minimizing	minimize	VERB
dti-1334	222	81	non	non	ADJ
dti-1334	222	82	malignant	malignant	ADJ
dti-1334	222	83	cell	cell	NOUN
dti-1334	222	84	uptake	uptake	ADJ
dti-1334	222	85	and	and	CCONJ
dti-1334	222	86	limiting	limit	VERB
dti-1334	222	87	potential	potential	ADJ
dti-1334	222	88	toxic	toxic	ADJ
dti-1334	222	89	effects	effect	NOUN
dti-1334	222	90	to	to	ADP
dti-1334	222	91	non	non	ADJ
dti-1334	222	92	target	target	NOUN
dti-1334	222	93	agents	agent	NOUN
dti-1334	222	94	(	(	PUNCT
dti-1334	222	95	dickins	dickin	NOUN
dti-1334	222	96	et	et	PROPN
dti-1334	222	97	al	al	PROPN
dti-1334	222	98	.	.	PROPN
dti-1334	222	99	2005	2005	NUM
dti-1334	222	100	;	;	PUNCT
dti-1334	222	101	gossen	gossen	NOUN
dti-1334	222	102	and	and	CCONJ
dti-1334	222	103	bujard	bujard	PROPN
dti-1334	222	104	,	,	PUNCT
dti-1334	222	105	1992	1992	NUM
dti-1334	222	106	;	;	PUNCT
dti-1334	222	107	grimm	grimm	NOUN
dti-1334	222	108	and	and	CCONJ
dti-1334	222	109	kay	kay	PROPN
dti-1334	222	110	,	,	PUNCT
dti-1334	222	111	2006	2006	NUM
dti-1334	222	112	;	;	PUNCT
dti-1334	222	113	gu	gu	NOUN
dti-1334	222	114	and	and	CCONJ
dti-1334	222	115	fang	fang	X
dti-1334	222	116	,	,	PUNCT
dti-1334	222	117	2003	2003	NUM
dti-1334	222	118	;	;	PUNCT
dti-1334	222	119	gupta	gupta	PROPN
dti-1334	222	120	et	et	PROPN
dti-1334	222	121	al	al	PROPN
dti-1334	222	122	.	.	PROPN
dti-1334	222	123	2004	2004	NUM
dti-1334	222	124	;	;	PUNCT
dti-1334	222	125	yu	yu	PROPN
dti-1334	222	126	et	et	PROPN
dti-1334	222	127	al	al	PROPN
dti-1334	222	128	.	.	PROPN
dti-1334	222	129	2002	2002	NUM
dti-1334	222	130	)	)	PUNCT
dti-1334	222	131	.	.	PUNCT
dti-1334	223	1	comparing	compare	VERB
dti-1334	223	2	patient	patient	NOUN
dti-1334	223	3	-	-	PUNCT
dti-1334	223	4	specifi	specifi	NOUN
dti-1334	223	5	c	c	PROPN
dti-1334	223	6	molecular	molecular	ADJ
dti-1334	223	7	profi	profi	NOUN
dti-1334	223	8	les	le	NOUN
dti-1334	223	9	with	with	ADP
dti-1334	223	10	known	know	VERB
dti-1334	223	11	and	and	CCONJ
dti-1334	223	12	developing	develop	VERB
dti-1334	223	13	human	human	ADJ
dti-1334	223	14	tissue	tissue	NOUN
dti-1334	223	15	-	-	PUNCT
dti-1334	223	16	based	base	VERB
dti-1334	223	17	pathways	pathway	NOUN
dti-1334	223	18	and	and	CCONJ
dti-1334	223	19	with	with	ADP
dti-1334	223	20	networks	network	NOUN
dti-1334	223	21	derived	derive	VERB
dti-1334	223	22	from	from	ADP
dti-1334	223	23	protein	protein	NOUN
dti-1334	223	24	interaction	interaction	NOUN
dti-1334	223	25	databases	database	NOUN
dti-1334	223	26	provides	provide	VERB
dti-1334	223	27	a	a	DET
dti-1334	223	28	means	mean	NOUN
dti-1334	223	29	for	for	ADP
dti-1334	223	30	identifying	identify	VERB
dti-1334	223	31	biologically	biologically	ADV
dti-1334	223	32	relevent	relevent	ADJ
dti-1334	223	33	oncodependent	oncodependent	ADJ
dti-1334	223	34	target	target	NOUN
dti-1334	223	35	clusters	cluster	NOUN
dti-1334	223	36	—	—	PUNCT
dti-1334	223	37	in	in	ADP
dti-1334	223	38	other	other	ADJ
dti-1334	223	39	words	word	NOUN
dti-1334	223	40	,	,	PUNCT
dti-1334	223	41	“	"	PUNCT
dti-1334	223	42	matching	match	VERB
dti-1334	223	43	up	up	ADP
dti-1334	223	44	the	the	DET
dti-1334	223	45	right	right	ADJ
dti-1334	223	46	patient	patient	NOUN
dti-1334	223	47	with	with	ADP
dti-1334	223	48	the	the	DET
dti-1334	223	49	right	right	ADJ
dti-1334	223	50	therapeutic	therapeutic	ADJ
dti-1334	223	51	”	"	PUNCT
dti-1334	223	52	.	.	PUNCT
dti-1334	224	1	references	reference	NOUN
dti-1334	224	2	aggarwal	aggarwal	PROPN
dti-1334	224	3	,	,	PUNCT
dti-1334	224	4	k.	k.	PROPN
dti-1334	224	5	,	,	PUNCT
dti-1334	224	6	choe	choe	PROPN
dti-1334	224	7	,	,	PUNCT
dti-1334	224	8	l.h	l.h	PROPN
dti-1334	224	9	.	.	PROPN
dti-1334	224	10	and	and	CCONJ
dti-1334	224	11	lee	lee	PROPN
dti-1334	224	12	,	,	PUNCT
dti-1334	224	13	k.h	k.h	PROPN
dti-1334	224	14	.	.	PROPN
dti-1334	224	15	2006	2006	NUM
dti-1334	224	16	.	.	PUNCT
dti-1334	225	1	shotgun	shotgun	NOUN
dti-1334	225	2	proteomics	proteomic	NOUN
dti-1334	225	3	using	use	VERB
dti-1334	225	4	the	the	DET
dti-1334	225	5	itraq	itraq	PROPN
dti-1334	225	6	.	.	PUNCT
dti-1334	226	1	isobaric	isobaric	ADJ
dti-1334	226	2	tags	tag	NOUN
dti-1334	226	3	.	.	PUNCT
dti-1334	227	1	brief	brief	ADJ
dti-1334	227	2	funct	funct	ADJ
dti-1334	227	3	genomic	genomic	NOUN
dti-1334	227	4	proteomic	proteomic	NOUN
dti-1334	227	5	,	,	PUNCT
dti-1334	227	6	5:112–20	5:112–20	PROPN
dti-1334	227	7	.	.	PUNCT
dti-1334	228	1	ajani	ajani	PROPN
dti-1334	228	2	,	,	PUNCT
dti-1334	228	3	j.	j.	PROPN
dti-1334	228	4	and	and	CCONJ
dti-1334	228	5	allgood	allgood	PROPN
dti-1334	228	6	,	,	PUNCT
dti-1334	228	7	v.	v.	ADP
dti-1334	228	8	2005	2005	NUM
dti-1334	228	9	.	.	PUNCT
dti-1334	229	1	molecular	molecular	ADJ
dti-1334	229	2	mechanisms	mechanism	NOUN
dti-1334	229	3	in	in	ADP
dti-1334	229	4	cancer	cancer	NOUN
dti-1334	229	5	:	:	PUNCT
dti-1334	229	6	what	what	PRON
dti-1334	229	7	should	should	AUX
dti-1334	229	8	clinicians	clinician	NOUN
dti-1334	229	9	know	know	VERB
dti-1334	229	10	?	?	PUNCT
dti-1334	230	1	semin	semin	PROPN
dti-1334	230	2	.	.	PUNCT
dti-1334	231	1	oncol	oncol	PROPN
dti-1334	231	2	.	.	PUNCT
dti-1334	231	3	,	,	PUNCT
dti-1334	231	4	32:2–4	32:2–4	NOUN
dti-1334	231	5	.	.	PUNCT
dti-1334	232	1	aksenov	aksenov	PROPN
dti-1334	232	2	,	,	PUNCT
dti-1334	232	3	s.v	s.v	PROPN
dti-1334	232	4	.	.	PROPN
dti-1334	232	5	,	,	PUNCT
dti-1334	232	6	church	church	PROPN
dti-1334	232	7	,	,	PUNCT
dti-1334	232	8	b.	b.	PROPN
dti-1334	232	9	,	,	PUNCT
dti-1334	232	10	dhiman	dhiman	NOUN
dti-1334	232	11	,	,	PUNCT
dti-1334	232	12	a.	a.	NOUN
dti-1334	232	13	,	,	PUNCT
dti-1334	232	14	georgieva	georgieva	PROPN
dti-1334	232	15	,	,	PUNCT
dti-1334	232	16	a.	a.	NOUN
dti-1334	232	17	,	,	PUNCT
dti-1334	232	18	sarangapani	sarangapani	PROPN
dti-1334	232	19	,	,	PUNCT
dti-1334	232	20	r.	r.	PROPN
dti-1334	232	21	,	,	PUNCT
dti-1334	232	22	helmlinger	helmlinger	PROPN
dti-1334	232	23	,	,	PUNCT
dti-1334	232	24	g.	g.	PROPN
dti-1334	232	25	and	and	CCONJ
dti-1334	232	26	khalil	khalil	PROPN
dti-1334	232	27	,	,	PUNCT
dti-1334	232	28	i.g	i.g	PROPN
dti-1334	232	29	.	.	PROPN
dti-1334	232	30	2005	2005	NUM
dti-1334	232	31	.	.	PUNCT
dti-1334	233	1	an	an	DET
dti-1334	233	2	integrated	integrated	ADJ
dti-1334	233	3	approach	approach	NOUN
dti-1334	233	4	for	for	ADP
dti-1334	233	5	inference	inference	NOUN
dti-1334	233	6	and	and	CCONJ
dti-1334	233	7	mechanistic	mechanistic	ADJ
dti-1334	233	8	modeling	modeling	NOUN
dti-1334	233	9	for	for	ADP
dti-1334	233	10	advancing	advance	VERB
dti-1334	233	11	drug	drug	NOUN
dti-1334	233	12	development	development	NOUN
dti-1334	233	13	.	.	PUNCT
dti-1334	234	1	febs	febs	PROPN
dti-1334	234	2	lett	lett	PROPN
dti-1334	234	3	,	,	PUNCT
dti-1334	234	4	579:1878–83	579:1878–83	PROPN
dti-1334	234	5	.	.	PUNCT
dti-1334	234	6	albert	albert	PROPN
dti-1334	234	7	,	,	PUNCT
dti-1334	234	8	r.	r.	PROPN
dti-1334	234	9	,	,	PUNCT
dti-1334	234	10	jeong	jeong	PROPN
dti-1334	234	11	,	,	PUNCT
dti-1334	234	12	h.	h.	PROPN
dti-1334	234	13	and	and	CCONJ
dti-1334	234	14	barabasi	barabasi	PROPN
dti-1334	234	15	,	,	PUNCT
dti-1334	234	16	a.l	a.l	PROPN
dti-1334	234	17	.	.	PROPN
dti-1334	234	18	2000	2000	NUM
dti-1334	234	19	.	.	PUNCT
dti-1334	235	1	error	error	NOUN
dti-1334	235	2	and	and	CCONJ
dti-1334	235	3	attack	attack	NOUN
dti-1334	235	4	tolerance	tolerance	NOUN
dti-1334	235	5	of	of	ADP
dti-1334	235	6	complex	complex	ADJ
dti-1334	235	7	networks	network	NOUN
dti-1334	235	8	.	.	PUNCT
dti-1334	236	1	nature	nature	NOUN
dti-1334	236	2	,	,	PUNCT
dti-1334	236	3	406:378–82	406:378–82	PROPN
dti-1334	236	4	.	.	PUNCT
dti-1334	237	1	ashburner	ashburner	NOUN
dti-1334	237	2	,	,	PUNCT
dti-1334	237	3	m.	m.	NOUN
dti-1334	237	4	,	,	PUNCT
dti-1334	237	5	ball	ball	NOUN
dti-1334	237	6	,	,	PUNCT
dti-1334	237	7	c.a	c.a	PROPN
dti-1334	237	8	.	.	PROPN
dti-1334	237	9	,	,	PUNCT
dti-1334	237	10	blake	blake	PROPN
dti-1334	237	11	,	,	PUNCT
dti-1334	237	12	j.a	j.a	PROPN
dti-1334	237	13	.	.	PROPN
dti-1334	237	14	,	,	PUNCT
dti-1334	237	15	botstein	botstein	PROPN
dti-1334	237	16	,	,	PUNCT
dti-1334	237	17	d.	d.	PROPN
dti-1334	237	18	,	,	PUNCT
dti-1334	237	19	butler	butler	PROPN
dti-1334	237	20	,	,	PUNCT
dti-1334	237	21	h.	h.	PROPN
dti-1334	237	22	,	,	PUNCT
dti-1334	237	23	cherry	cherry	NOUN
dti-1334	237	24	,	,	PUNCT
dti-1334	237	25	j.m	j.m	PROPN
dti-1334	237	26	.	.	PROPN
dti-1334	237	27	,	,	PUNCT
dti-1334	237	28	davis	davis	PROPN
dti-1334	237	29	,	,	PUNCT
dti-1334	237	30	a.p	a.p	PROPN
dti-1334	237	31	.	.	PROPN
dti-1334	237	32	,	,	PUNCT
dti-1334	237	33	dolinski	dolinski	PROPN
dti-1334	237	34	,	,	PUNCT
dti-1334	237	35	k.	k.	PROPN
dti-1334	237	36	,	,	PUNCT
dti-1334	237	37	dwight	dwight	PROPN
dti-1334	237	38	,	,	PUNCT
dti-1334	237	39	s.s	s.s	PROPN
dti-1334	237	40	.	.	PROPN
dti-1334	237	41	,	,	PUNCT
dti-1334	237	42	eppig	eppig	PROPN
dti-1334	237	43	,	,	PUNCT
dti-1334	237	44	j.t	j.t	PROPN
dti-1334	237	45	.	.	PROPN
dti-1334	237	46	,	,	PUNCT
dti-1334	237	47	harris	harris	PROPN
dti-1334	237	48	,	,	PUNCT
dti-1334	237	49	m.a	m.a	PROPN
dti-1334	237	50	.	.	PROPN
dti-1334	237	51	,	,	PUNCT
dti-1334	237	52	hill	hill	PROPN
dti-1334	237	53	,	,	PUNCT
dti-1334	237	54	d.p	d.p	PROPN
dti-1334	237	55	.	.	PROPN
dti-1334	237	56	,	,	PUNCT
dti-1334	237	57	issel	issel	NOUN
dti-1334	237	58	-	-	PUNCT
dti-1334	237	59	tarver	tarver	PROPN
dti-1334	237	60	,	,	PUNCT
dti-1334	237	61	l.	l.	PROPN
dti-1334	237	62	,	,	PUNCT
dti-1334	237	63	kasarskis	kasarskis	PROPN
dti-1334	237	64	,	,	PUNCT
dti-1334	237	65	a.	a.	PROPN
dti-1334	237	66	,	,	PUNCT
dti-1334	237	67	lewis	lewis	PROPN
dti-1334	237	68	,	,	PUNCT
dti-1334	237	69	s.	s.	PROPN
dti-1334	237	70	,	,	PUNCT
dti-1334	237	71	matese	matese	NOUN
dti-1334	237	72	,	,	PUNCT
dti-1334	237	73	j.c	j.c	PROPN
dti-1334	237	74	.	.	PROPN
dti-1334	237	75	,	,	PUNCT
dti-1334	237	76	richardson	richardson	PROPN
dti-1334	237	77	,	,	PUNCT
dti-1334	237	78	j.e	j.e	PROPN
dti-1334	237	79	.	.	PROPN
dti-1334	237	80	,	,	PUNCT
dti-1334	237	81	ringwald	ringwald	PROPN
dti-1334	237	82	,	,	PUNCT
dti-1334	237	83	m.	m.	NOUN
dti-1334	237	84	,	,	PUNCT
dti-1334	237	85	rubin	rubin	PROPN
dti-1334	237	86	,	,	PUNCT
dti-1334	237	87	g.m	g.m	PROPN
dti-1334	237	88	.	.	PROPN
dti-1334	237	89	and	and	CCONJ
dti-1334	237	90	sherlock	sherlock	PROPN
dti-1334	237	91	,	,	PUNCT
dti-1334	237	92	g.	g.	PROPN
dti-1334	237	93	2000	2000	NUM
dti-1334	237	94	.	.	PUNCT
dti-1334	238	1	gene	gene	NOUN
dti-1334	238	2	ontology	ontology	NOUN
dti-1334	238	3	:	:	PUNCT
dti-1334	238	4	tool	tool	NOUN
dti-1334	238	5	for	for	ADP
dti-1334	238	6	the	the	DET
dti-1334	238	7	unifi	unifi	NOUN
dti-1334	238	8	cation	cation	NOUN
dti-1334	238	9	of	of	ADP
dti-1334	238	10	biology	biology	NOUN
dti-1334	238	11	.	.	PUNCT
dti-1334	239	1	the	the	DET
dti-1334	239	2	gene	gene	NOUN
dti-1334	239	3	ontology	ontology	NOUN
dti-1334	239	4	consortium	consortium	NOUN
dti-1334	239	5	.	.	PUNCT
dti-1334	240	1	nat	nat	PROPN
dti-1334	240	2	.	.	PUNCT
dti-1334	241	1	genet	genet	PROPN
dti-1334	241	2	.	.	PUNCT
dti-1334	241	3	,	,	PUNCT
dti-1334	241	4	25:25–9	25:25–9	NOUN
dti-1334	241	5	.	.	PUNCT
dti-1334	242	1	bader	bader	PROPN
dti-1334	242	2	,	,	PUNCT
dti-1334	242	3	g.d	g.d	PROPN
dti-1334	242	4	.	.	PROPN
dti-1334	242	5	,	,	PUNCT
dti-1334	242	6	donaldson	donaldson	PROPN
dti-1334	242	7	,	,	PUNCT
dti-1334	242	8	i.	i.	PROPN
dti-1334	242	9	,	,	PUNCT
dti-1334	242	10	wolting	wolting	NOUN
dti-1334	242	11	,	,	PUNCT
dti-1334	242	12	c.	c.	PROPN
dti-1334	242	13	,	,	PUNCT
dti-1334	242	14	ouellette	ouellette	PROPN
dti-1334	242	15	,	,	PUNCT
dti-1334	242	16	b.f	b.f	PROPN
dti-1334	242	17	.	.	PROPN
dti-1334	242	18	,	,	PUNCT
dti-1334	242	19	pawson	pawson	PROPN
dti-1334	242	20	,	,	PUNCT
dti-1334	242	21	t.	t.	PROPN
dti-1334	242	22	and	and	CCONJ
dti-1334	242	23	hogue	hogue	PROPN
dti-1334	242	24	,	,	PUNCT
dti-1334	242	25	c.w	c.w	PROPN
dti-1334	242	26	.	.	PROPN
dti-1334	242	27	2001	2001	NUM
dti-1334	242	28	.	.	PUNCT
dti-1334	243	1	bind	bind	VERB
dti-1334	243	2	—	—	PUNCT
dti-1334	243	3	the	the	DET
dti-1334	243	4	biomolecular	biomolecular	ADJ
dti-1334	243	5	interaction	interaction	NOUN
dti-1334	243	6	network	network	NOUN
dti-1334	243	7	database	database	NOUN
dti-1334	243	8	.	.	PUNCT
dti-1334	244	1	nucleic	nucleic	ADJ
dti-1334	244	2	acids	acid	NOUN
dti-1334	244	3	res	re	NOUN
dti-1334	244	4	.	.	PROPN
dti-1334	244	5	,	,	PUNCT
dti-1334	244	6	29:242–5	29:242–5	NUM
dti-1334	244	7	.	.	PUNCT
dti-1334	245	1	becker	becker	PROPN
dti-1334	245	2	,	,	PUNCT
dti-1334	245	3	k.f	k.f	PROPN
dti-1334	245	4	.	.	PROPN
dti-1334	245	5	,	,	PUNCT
dti-1334	245	6	metzger	metzger	PROPN
dti-1334	245	7	,	,	PUNCT
dti-1334	245	8	v.	v.	PROPN
dti-1334	245	9	,	,	PUNCT
dti-1334	245	10	hipp	hipp	PROPN
dti-1334	245	11	,	,	PUNCT
dti-1334	245	12	s.	s.	PROPN
dti-1334	245	13	and	and	CCONJ
dti-1334	245	14	hofl	hofl	ADJ
dti-1334	245	15	er	er	INTJ
dti-1334	245	16	,	,	PUNCT
dti-1334	245	17	h.	h.	PROPN
dti-1334	245	18	2006	2006	NUM
dti-1334	245	19	.	.	PUNCT
dti-1334	246	1	clinical	clinical	ADJ
dti-1334	246	2	proteomics	proteomic	NOUN
dti-1334	246	3	:	:	PUNCT
dti-1334	246	4	new	new	ADJ
dti-1334	246	5	trends	trend	NOUN
dti-1334	246	6	for	for	ADP
dti-1334	246	7	protein	protein	NOUN
dti-1334	246	8	microarrays	microarray	NOUN
dti-1334	246	9	.	.	PUNCT
dti-1334	247	1	curr	curr	AUX
dti-1334	247	2	.	.	PUNCT
dti-1334	247	3	med	med	PROPN
dti-1334	247	4	.	.	PROPN
dti-1334	247	5	chem	chem	PROPN
dti-1334	247	6	.	.	PUNCT
dti-1334	247	7	,	,	PUNCT
dti-1334	248	1	13:1831–7	13:1831–7	X
dti-1334	248	2	.	.	PUNCT
dti-1334	248	3	bhattacharjee	bhattacharjee	PROPN
dti-1334	248	4	,	,	PUNCT
dti-1334	248	5	a.	a.	PROPN
dti-1334	248	6	,	,	PUNCT
dti-1334	248	7	richards	richards	PROPN
dti-1334	248	8	,	,	PUNCT
dti-1334	248	9	w.g	w.g	PROPN
dti-1334	248	10	.	.	PROPN
dti-1334	248	11	,	,	PUNCT
dti-1334	248	12	staunton	staunton	PROPN
dti-1334	248	13	,	,	PUNCT
dti-1334	248	14	j.	j.	PROPN
dti-1334	248	15	,	,	PUNCT
dti-1334	248	16	li	li	PROPN
dti-1334	248	17	,	,	PUNCT
dti-1334	248	18	c.	c.	PROPN
dti-1334	248	19	,	,	PUNCT
dti-1334	248	20	monti	monti	PROPN
dti-1334	248	21	,	,	PUNCT
dti-1334	248	22	s.	s.	PROPN
dti-1334	248	23	,	,	PUNCT
dti-1334	248	24	vasa	vasa	NOUN
dti-1334	248	25	,	,	PUNCT
dti-1334	248	26	p.	p.	NOUN
dti-1334	248	27	,	,	PUNCT
dti-1334	248	28	ladd	ladd	PROPN
dti-1334	248	29	,	,	PUNCT
dti-1334	248	30	c.	c.	NOUN
dti-1334	248	31	,	,	PUNCT
dti-1334	248	32	beheshti	beheshti	PROPN
dti-1334	248	33	,	,	PUNCT
dti-1334	248	34	j.	j.	PROPN
dti-1334	248	35	,	,	PUNCT
dti-1334	248	36	bueno	bueno	PROPN
dti-1334	248	37	,	,	PUNCT
dti-1334	248	38	r.	r.	PROPN
dti-1334	248	39	,	,	PUNCT
dti-1334	248	40	gillette	gillette	PROPN
dti-1334	248	41	,	,	PUNCT
dti-1334	248	42	m.	m.	NOUN
dti-1334	248	43	,	,	PUNCT
dti-1334	248	44	loda	loda	PROPN
dti-1334	248	45	,	,	PUNCT
dti-1334	248	46	m.	m.	NOUN
dti-1334	248	47	,	,	PUNCT
dti-1334	248	48	weber	weber	PROPN
dti-1334	248	49	,	,	PUNCT
dti-1334	248	50	g.	g.	PROPN
dti-1334	248	51	,	,	PUNCT
dti-1334	248	52	mark	mark	PROPN
dti-1334	248	53	,	,	PUNCT
dti-1334	248	54	e.j	e.j	PROPN
dti-1334	248	55	.	.	PROPN
dti-1334	248	56	,	,	PUNCT
dti-1334	248	57	lander	lander	PROPN
dti-1334	248	58	,	,	PUNCT
dti-1334	248	59	e.s	e.s	PROPN
dti-1334	248	60	.	.	PROPN
dti-1334	248	61	,	,	PUNCT
dti-1334	248	62	wong	wong	PROPN
dti-1334	248	63	,	,	PUNCT
dti-1334	248	64	w.	w.	PROPN
dti-1334	248	65	,	,	PUNCT
dti-1334	248	66	johnson	johnson	PROPN
dti-1334	248	67	,	,	PUNCT
dti-1334	248	68	b.e	b.e	PROPN
dti-1334	248	69	.	.	PROPN
dti-1334	248	70	,	,	PUNCT
dti-1334	248	71	golub	golub	PROPN
dti-1334	248	72	,	,	PUNCT
dti-1334	248	73	t.r	t.r	PROPN
dti-1334	248	74	.	.	PROPN
dti-1334	248	75	,	,	PUNCT
dti-1334	248	76	sugarbaker	sugarbaker	PROPN
dti-1334	248	77	,	,	PUNCT
dti-1334	248	78	d.j	d.j	PROPN
dti-1334	248	79	.	.	PROPN
dti-1334	248	80	and	and	CCONJ
dti-1334	248	81	meyerson	meyerson	PROPN
dti-1334	248	82	,	,	PUNCT
dti-1334	248	83	m.	m.	NOUN
dti-1334	248	84	2001	2001	NUM
dti-1334	248	85	.	.	PUNCT
dti-1334	249	1	classifi	classifi	PROPN
dti-1334	249	2	cation	cation	NOUN
dti-1334	249	3	of	of	ADP
dti-1334	249	4	human	human	ADJ
dti-1334	249	5	lung	lung	NOUN
dti-1334	249	6	carcinomas	carcinoma	NOUN
dti-1334	249	7	by	by	ADP
dti-1334	249	8	mrna	mrna	PROPN
dti-1334	249	9	expression	expression	NOUN
dti-1334	249	10	profi	profi	PROPN
dti-1334	249	11	ling	ling	PROPN
dti-1334	249	12	reveals	reveal	VERB
dti-1334	249	13	distinct	distinct	ADJ
dti-1334	249	14	adenocarcinoma	adenocarcinoma	NOUN
dti-1334	249	15	subclasses	subclass	NOUN
dti-1334	249	16	.	.	PUNCT
dti-1334	250	1	proc	proc	NOUN
dti-1334	250	2	.	.	PUNCT
dti-1334	251	1	natl	natl	PROPN
dti-1334	251	2	.	.	PUNCT
dti-1334	252	1	acad	acad	PROPN
dti-1334	252	2	.	.	PUNCT
dti-1334	253	1	sci	sci	PROPN
dti-1334	253	2	.	.	PUNCT
dti-1334	253	3	u.s.a	u.s.a	PROPN
dti-1334	253	4	.	.	PROPN
dti-1334	253	5	,	,	PUNCT
dti-1334	253	6	98:13790–5	98:13790–5	NUM
dti-1334	253	7	.	.	PUNCT
dti-1334	254	1	bohannon	bohannon	PROPN
dti-1334	254	2	,	,	PUNCT
dti-1334	254	3	j.	j.	PROPN
dti-1334	254	4	2002	2002	NUM
dti-1334	254	5	.	.	PUNCT
dti-1334	255	1	bioinformatics	bioinformatic	NOUN
dti-1334	255	2	.	.	PUNCT
dti-1334	256	1	the	the	DET
dti-1334	256	2	human	human	ADJ
dti-1334	256	3	genome	genome	NOUN
dti-1334	256	4	in	in	ADP
dti-1334	256	5	3d	3d	NUM
dti-1334	256	6	,	,	PUNCT
dti-1334	256	7	at	at	ADP
dti-1334	256	8	your	your	PRON
dti-1334	256	9	fi	fi	NOUN
dti-1334	256	10	ngertips	ngertip	NOUN
dti-1334	256	11	.	.	PUNCT
dti-1334	257	1	science	science	NOUN
dti-1334	257	2	,	,	PUNCT
dti-1334	257	3	298:737	298:737	NUM
dti-1334	257	4	.	.	PUNCT
dti-1334	257	5	bohler	bohler	NOUN
dti-1334	257	6	,	,	PUNCT
dti-1334	257	7	s.	s.	PROPN
dti-1334	257	8	,	,	PUNCT
dti-1334	257	9	bagard	bagard	NOUN
dti-1334	257	10	,	,	PUNCT
dti-1334	257	11	m.	m.	NOUN
dti-1334	257	12	,	,	PUNCT
dti-1334	257	13	oufi	oufi	ADJ
dti-1334	257	14	r	r	NOUN
dti-1334	257	15	,	,	PUNCT
dti-1334	257	16	m.	m.	NOUN
dti-1334	257	17	,	,	PUNCT
dti-1334	257	18	planchon	planchon	PROPN
dti-1334	257	19	,	,	PUNCT
dti-1334	257	20	s.	s.	PROPN
dti-1334	257	21	,	,	PUNCT
dti-1334	257	22	hoffmann	hoffmann	PROPN
dti-1334	257	23	,	,	PUNCT
dti-1334	257	24	l.	l.	PROPN
dti-1334	257	25	,	,	PUNCT
dti-1334	257	26	jolivet	jolivet	NOUN
dti-1334	257	27	,	,	PUNCT
dti-1334	257	28	y.	y.	PROPN
dti-1334	257	29	,	,	PUNCT
dti-1334	257	30	hausman	hausman	PROPN
dti-1334	257	31	,	,	PUNCT
dti-1334	257	32	j.f	j.f	PROPN
dti-1334	257	33	.	.	PROPN
dti-1334	257	34	,	,	PUNCT
dti-1334	257	35	dizengremel	dizengremel	NOUN
dti-1334	257	36	,	,	PUNCT
dti-1334	257	37	p.	p.	NOUN
dti-1334	257	38	and	and	CCONJ
dti-1334	257	39	renaut	renaut	PROPN
dti-1334	257	40	,	,	PUNCT
dti-1334	257	41	j.	j.	PROPN
dti-1334	257	42	2007	2007	NUM
dti-1334	257	43	.	.	PUNCT
dti-1334	258	1	a	a	DET
dti-1334	258	2	dige	dige	NOUN
dti-1334	258	3	analysis	analysis	NOUN
dti-1334	258	4	of	of	ADP
dti-1334	258	5	developing	develop	VERB
dti-1334	258	6	poplar	poplar	ADJ
dti-1334	258	7	leaves	leave	NOUN
dti-1334	258	8	subjected	subject	VERB
dti-1334	258	9	to	to	ADP
dti-1334	258	10	ozone	ozone	NOUN
dti-1334	258	11	reveals	reveal	VERB
dti-1334	258	12	major	major	ADJ
dti-1334	258	13	changes	change	NOUN
dti-1334	258	14	in	in	ADP
dti-1334	258	15	carbon	carbon	NOUN
dti-1334	258	16	metabolism	metabolism	NOUN
dti-1334	258	17	.	.	PUNCT
dti-1334	259	1	proteomics	proteomic	NOUN
dti-1334	259	2	,	,	PUNCT
dti-1334	259	3	7:1584–99	7:1584–99	PROPN
dti-1334	259	4	.	.	PUNCT
dti-1334	260	1	bonner	bonner	PROPN
dti-1334	260	2	,	,	PUNCT
dti-1334	260	3	r.f	r.f	PROPN
dti-1334	260	4	.	.	PROPN
dti-1334	260	5	,	,	PUNCT
dti-1334	260	6	emmert	emmert	NOUN
dti-1334	260	7	-	-	PUNCT
dti-1334	260	8	buck	buck	NOUN
dti-1334	260	9	,	,	PUNCT
dti-1334	260	10	m.	m.	NOUN
dti-1334	260	11	,	,	PUNCT
dti-1334	260	12	cole	cole	PROPN
dti-1334	260	13	,	,	PUNCT
dti-1334	260	14	k.	k.	PROPN
dti-1334	260	15	,	,	PUNCT
dti-1334	260	16	pohida	pohida	PROPN
dti-1334	260	17	,	,	PUNCT
dti-1334	260	18	t.	t.	PROPN
dti-1334	260	19	,	,	PUNCT
dti-1334	260	20	chuaqui	chuaqui	PROPN
dti-1334	260	21	,	,	PUNCT
dti-1334	260	22	r.	r.	PROPN
dti-1334	260	23	,	,	PUNCT
dti-1334	260	24	goldstein	goldstein	PROPN
dti-1334	260	25	,	,	PUNCT
dti-1334	260	26	s.	s.	PROPN
dti-1334	260	27	and	and	CCONJ
dti-1334	260	28	liotta	liotta	PROPN
dti-1334	260	29	,	,	PUNCT
dti-1334	260	30	l.a	l.a	PROPN
dti-1334	260	31	.	.	PROPN
dti-1334	260	32	1997	1997	NUM
dti-1334	260	33	.	.	PUNCT
dti-1334	261	1	laser	laser	NOUN
dti-1334	261	2	capture	capture	NOUN
dti-1334	261	3	microdissection	microdissection	NOUN
dti-1334	261	4	:	:	PUNCT
dti-1334	261	5	molecular	molecular	ADJ
dti-1334	261	6	analysis	analysis	NOUN
dti-1334	261	7	of	of	ADP
dti-1334	261	8	tissue	tissue	NOUN
dti-1334	261	9	.	.	PUNCT
dti-1334	262	1	science	science	NOUN
dti-1334	262	2	,	,	PUNCT
dti-1334	262	3	278:1481,1483	278:1481,1483	NUM
dti-1334	262	4	.	.	PROPN
dti-1334	262	5	borrebaeck	borrebaeck	PROPN
dti-1334	262	6	,	,	PUNCT
dti-1334	262	7	c.a	c.a	PROPN
dti-1334	262	8	.	.	PROPN
dti-1334	262	9	2006	2006	NUM
dti-1334	262	10	.	.	PUNCT
dti-1334	263	1	antibody	antibody	NOUN
dti-1334	263	2	microarray	microarray	NOUN
dti-1334	263	3	-	-	PUNCT
dti-1334	263	4	based	base	VERB
dti-1334	263	5	oncoproteomics	oncoproteomic	NOUN
dti-1334	263	6	.	.	PUNCT
dti-1334	264	1	expert	expert	NOUN
dti-1334	264	2	opin	opin	NOUN
dti-1334	264	3	.	.	PUNCT
dti-1334	265	1	biol	biol	PROPN
dti-1334	265	2	.	.	PUNCT
dti-1334	266	1	ther	ther	PROPN
dti-1334	266	2	.	.	PUNCT
dti-1334	266	3	,	,	PUNCT
dti-1334	266	4	6:833–8	6:833–8	X
dti-1334	266	5	.	.	PUNCT
dti-1334	267	1	bouyssie	bouyssie	PROPN
dti-1334	267	2	,	,	PUNCT
dti-1334	267	3	d.	d.	PROPN
dti-1334	267	4	,	,	PUNCT
dti-1334	267	5	gonzalez	gonzalez	PROPN
dti-1334	267	6	de	de	PROPN
dti-1334	267	7	peredo	peredo	PROPN
dti-1334	267	8	,	,	PUNCT
dti-1334	267	9	a.	a.	NOUN
dti-1334	267	10	,	,	PUNCT
dti-1334	267	11	mouton	mouton	PROPN
dti-1334	267	12	,	,	PUNCT
dti-1334	267	13	e.	e.	PROPN
dti-1334	267	14	,	,	PUNCT
dti-1334	267	15	albigot	albigot	PROPN
dti-1334	267	16	,	,	PUNCT
dti-1334	267	17	r.	r.	PROPN
dti-1334	267	18	,	,	PUNCT
dti-1334	267	19	roussel	roussel	PROPN
dti-1334	267	20	,	,	PUNCT
dti-1334	267	21	l.	l.	PROPN
dti-1334	267	22	,	,	PUNCT
dti-1334	267	23	ortega	ortega	PROPN
dti-1334	267	24	,	,	PUNCT
dti-1334	267	25	n.	n.	NOUN
dti-1334	267	26	,	,	PUNCT
dti-1334	267	27	cayrol	cayrol	NOUN
dti-1334	267	28	,	,	PUNCT
dti-1334	267	29	c.	c.	NOUN
dti-1334	267	30	,	,	PUNCT
dti-1334	267	31	burlet	burlet	NOUN
dti-1334	267	32	-	-	PUNCT
dti-1334	267	33	schiltz	schiltz	NOUN
dti-1334	267	34	,	,	PUNCT
dti-1334	267	35	o.	o.	PROPN
dti-1334	267	36	,	,	PUNCT
dti-1334	267	37	girard	girard	PROPN
dti-1334	267	38	,	,	PUNCT
dti-1334	267	39	j.p	j.p	PROPN
dti-1334	267	40	.	.	PROPN
dti-1334	267	41	and	and	CCONJ
dti-1334	267	42	monsarrat	monsarrat	PROPN
dti-1334	267	43	,	,	PUNCT
dti-1334	267	44	b.	b.	PROPN
dti-1334	267	45	2007	2007	NUM
dti-1334	267	46	.	.	PUNCT
dti-1334	268	1	mfpaq	mfpaq	NOUN
dti-1334	268	2	,	,	PUNCT
dti-1334	268	3	a	a	DET
dti-1334	268	4	new	new	ADJ
dti-1334	268	5	software	software	NOUN
dti-1334	268	6	to	to	PART
dti-1334	268	7	parse	parse	VERB
dti-1334	268	8	,	,	PUNCT
dti-1334	268	9	validate	validate	VERB
dti-1334	268	10	,	,	PUNCT
dti-1334	268	11	and	and	CCONJ
dti-1334	268	12	quantify	quantify	VERB
dti-1334	268	13	proteomic	proteomic	ADJ
dti-1334	268	14	data	datum	NOUN
dti-1334	268	15	generated	generate	VERB
dti-1334	268	16	by	by	ADP
dti-1334	268	17	icat	icat	NOUN
dti-1334	268	18	and	and	CCONJ
dti-1334	268	19	silac	silac	PROPN
dti-1334	268	20	mass	mass	PROPN
dti-1334	268	21	spectrometric	spectrometric	ADJ
dti-1334	268	22	analyses	analysis	NOUN
dti-1334	268	23	:	:	PUNCT
dti-1334	268	24	application	application	NOUN
dti-1334	268	25	to	to	ADP
dti-1334	268	26	the	the	DET
dti-1334	268	27	proteomic	proteomic	ADJ
dti-1334	268	28	study	study	NOUN
dti-1334	268	29	of	of	ADP
dti-1334	268	30	membrane	membrane	NOUN
dti-1334	268	31	proteins	protein	NOUN
dti-1334	268	32	from	from	ADP
dti-1334	268	33	primary	primary	ADJ
dti-1334	268	34	human	human	ADJ
dti-1334	268	35	endothelial	endothelial	NOUN
dti-1334	268	36	cells	cell	NOUN
dti-1334	268	37	.	.	PUNCT
dti-1334	269	1	mol	mol	PROPN
dti-1334	269	2	.	.	PROPN
dti-1334	269	3	cell	cell	NOUN
dti-1334	269	4	.	.	PUNCT
dti-1334	270	1	proteomics	proteomic	NOUN
dti-1334	270	2	.	.	PUNCT
dti-1334	271	1	breci	breci	NOUN
dti-1334	271	2	,	,	PUNCT
dti-1334	271	3	l.	l.	PROPN
dti-1334	271	4	and	and	CCONJ
dti-1334	271	5	haynes	haynes	PROPN
dti-1334	271	6	,	,	PUNCT
dti-1334	271	7	p.a	p.a	PROPN
dti-1334	271	8	.	.	PROPN
dti-1334	271	9	2007	2007	NUM
dti-1334	271	10	.	.	PUNCT
dti-1334	272	1	two	two	NUM
dti-1334	272	2	-	-	PUNCT
dti-1334	272	3	dimensional	dimensional	ADJ
dti-1334	272	4	nanofl	nanofl	NOUN
dti-1334	272	5	ow	ow	INTJ
dti-1334	272	6	liquid	liquid	ADJ
dti-1334	272	7	chromatography	chromatography	NOUN
dti-1334	272	8	-	-	PUNCT
dti-1334	272	9	tandem	tandem	NOUN
dti-1334	272	10	mass	mass	ADJ
dti-1334	272	11	spectrometry	spectrometry	NOUN
dti-1334	272	12	of	of	ADP
dti-1334	272	13	proteins	protein	NOUN
dti-1334	272	14	extracted	extract	VERB
dti-1334	272	15	from	from	ADP
dti-1334	272	16	rice	rice	NOUN
dti-1334	272	17	leaves	leave	NOUN
dti-1334	272	18	and	and	CCONJ
dti-1334	272	19	roots	root	NOUN
dti-1334	272	20	.	.	PUNCT
dti-1334	273	1	methods	method	NOUN
dti-1334	273	2	mol	mol	PROPN
dti-1334	273	3	.	.	PUNCT
dti-1334	274	1	biol	biol	PROPN
dti-1334	274	2	.	.	PUNCT
dti-1334	275	1	,	,	PUNCT
dti-1334	276	1	355:249–66	355:249–66	NUM
dti-1334	276	2	.	.	PUNCT
dti-1334	276	3	cannataro	cannataro	NOUN
dti-1334	276	4	,	,	PUNCT
dti-1334	276	5	m.	m.	NOUN
dti-1334	276	6	2008	2008	NUM
dti-1334	276	7	.	.	PUNCT
dti-1334	277	1	computational	computational	ADJ
dti-1334	277	2	proteomics	proteomic	NOUN
dti-1334	277	3	:	:	PUNCT
dti-1334	277	4	management	management	NOUN
dti-1334	277	5	and	and	CCONJ
dti-1334	277	6	analysis	analysis	NOUN
dti-1334	277	7	of	of	ADP
dti-1334	277	8	proteomics	proteomic	NOUN
dti-1334	277	9	data	datum	NOUN
dti-1334	277	10	.	.	PUNCT
dti-1334	278	1	brief	brief	ADJ
dti-1334	278	2	bioinform	bioinform	NOUN
dti-1334	278	3	.	.	PUNCT
dti-1334	279	1	carlson	carlson	PROPN
dti-1334	279	2	,	,	PUNCT
dti-1334	279	3	j.m	j.m	PROPN
dti-1334	279	4	.	.	PROPN
dti-1334	279	5	and	and	CCONJ
dti-1334	279	6	doyle	doyle	PROPN
dti-1334	279	7	,	,	PUNCT
dti-1334	279	8	j.	j.	PROPN
dti-1334	279	9	2002	2002	NUM
dti-1334	279	10	.	.	PUNCT
dti-1334	280	1	complexity	complexity	NOUN
dti-1334	280	2	and	and	CCONJ
dti-1334	280	3	robustness	robustness	NOUN
dti-1334	280	4	.	.	PUNCT
dti-1334	281	1	proc	proc	NOUN
dti-1334	281	2	.	.	PUNCT
dti-1334	282	1	natl	natl	PROPN
dti-1334	282	2	.	.	PUNCT
dti-1334	283	1	acad	acad	PROPN
dti-1334	283	2	.	.	PUNCT
dti-1334	284	1	sci	sci	PROPN
dti-1334	284	2	.	.	PUNCT
dti-1334	284	3	u.s.a	u.s.a	PROPN
dti-1334	284	4	.	.	PROPN
dti-1334	284	5	,	,	PUNCT
dti-1334	284	6	99(suppl	99(suppl	NUM
dti-1334	284	7	1):2538–45	1):2538–45	NUM
dti-1334	284	8	.	.	PUNCT
dti-1334	285	1	chen	chen	PROPN
dti-1334	285	2	,	,	PUNCT
dti-1334	285	3	x.	x.	PROPN
dti-1334	285	4	,	,	PUNCT
dti-1334	285	5	sun	sun	PROPN
dti-1334	285	6	,	,	PUNCT
dti-1334	285	7	l.	l.	PROPN
dti-1334	285	8	,	,	PUNCT
dti-1334	285	9	yu	yu	PROPN
dti-1334	285	10	,	,	PUNCT
dti-1334	285	11	y.	y.	PROPN
dti-1334	285	12	,	,	PUNCT
dti-1334	285	13	xue	xue	PROPN
dti-1334	285	14	,	,	PUNCT
dti-1334	285	15	y.	y.	PROPN
dti-1334	285	16	and	and	CCONJ
dti-1334	285	17	yang	yang	PROPN
dti-1334	285	18	,	,	PUNCT
dti-1334	285	19	p.	p.	NOUN
dti-1334	285	20	2007	2007	NUM
dti-1334	285	21	.	.	PUNCT
dti-1334	286	1	amino	amino	NOUN
dti-1334	286	2	acid	acid	NOUN
dti-1334	286	3	-	-	PUNCT
dti-1334	286	4	coded	code	VERB
dti-1334	286	5	tagging	tagging	NOUN
dti-1334	286	6	approaches	approach	NOUN
dti-1334	286	7	in	in	ADP
dti-1334	286	8	quantitative	quantitative	ADJ
dti-1334	286	9	proteomics	proteomic	NOUN
dti-1334	286	10	.	.	PUNCT
dti-1334	287	1	expert	expert	PROPN
dti-1334	287	2	rev	rev	PROPN
dti-1334	287	3	.	.	PROPN
dti-1334	287	4	proteomics	proteomic	NOUN
dti-1334	287	5	,	,	PUNCT
dti-1334	287	6	4:25–37	4:25–37	NOUN
dti-1334	287	7	.	.	PUNCT
dti-1334	288	1	cho	cho	PROPN
dti-1334	288	2	,	,	PUNCT
dti-1334	288	3	w.c	w.c	PROPN
dti-1334	288	4	.	.	PROPN
dti-1334	288	5	and	and	CCONJ
dti-1334	288	6	cheng	cheng	PROPN
dti-1334	288	7	,	,	PUNCT
dti-1334	288	8	c.h	c.h	PROPN
dti-1334	288	9	.	.	PROPN
dti-1334	288	10	2007	2007	NUM
dti-1334	288	11	.	.	PUNCT
dti-1334	289	1	oncoproteomics	oncoproteomic	NOUN
dti-1334	289	2	:	:	PUNCT
dti-1334	289	3	current	current	ADJ
dti-1334	289	4	trends	trend	NOUN
dti-1334	289	5	and	and	CCONJ
dti-1334	289	6	future	future	ADJ
dti-1334	289	7	perspectives	perspective	NOUN
dti-1334	289	8	.	.	PUNCT
dti-1334	290	1	expert	expert	NOUN
dti-1334	290	2	rev	rev	PROPN
dti-1334	290	3	.	.	PROPN
dti-1334	290	4	proteomics	proteomic	NOUN
dti-1334	290	5	,	,	PUNCT
dti-1334	291	1	4:401–10	4:401–10	PROPN
dti-1334	291	2	.	.	PUNCT
dti-1334	291	3	christopher	christopher	PROPN
dti-1334	291	4	,	,	PUNCT
dti-1334	291	5	r.	r.	PROPN
dti-1334	291	6	,	,	PUNCT
dti-1334	291	7	dhiman	dhiman	NOUN
dti-1334	291	8	,	,	PUNCT
dti-1334	291	9	a.	a.	NOUN
dti-1334	291	10	,	,	PUNCT
dti-1334	291	11	fox	fox	PROPN
dti-1334	291	12	,	,	PUNCT
dti-1334	291	13	j.	j.	PROPN
dti-1334	291	14	,	,	PUNCT
dti-1334	291	15	gendelman	gendelman	PROPN
dti-1334	291	16	,	,	PUNCT
dti-1334	291	17	r.	r.	PROPN
dti-1334	291	18	,	,	PUNCT
dti-1334	291	19	haberitcher	haberitcher	NOUN
dti-1334	291	20	,	,	PUNCT
dti-1334	291	21	t.	t.	PROPN
dti-1334	291	22	,	,	PUNCT
dti-1334	291	23	kagle	kagle	PROPN
dti-1334	291	24	,	,	PUNCT
dti-1334	291	25	d.	d.	PROPN
dti-1334	291	26	,	,	PUNCT
dti-1334	291	27	spizz	spizz	ADJ
dti-1334	291	28	,	,	PUNCT
dti-1334	291	29	g.	g.	PROPN
dti-1334	291	30	,	,	PUNCT
dti-1334	291	31	khalil	khalil	PROPN
dti-1334	291	32	,	,	PUNCT
dti-1334	291	33	i.g	i.g	PROPN
dti-1334	291	34	.	.	PROPN
dti-1334	291	35	and	and	CCONJ
dti-1334	291	36	hill	hill	PROPN
dti-1334	291	37	,	,	PUNCT
dti-1334	291	38	c.	c.	PROPN
dti-1334	291	39	2004	2004	NUM
dti-1334	291	40	.	.	PUNCT
dti-1334	292	1	data	data	NOUN
dti-1334	292	2	-	-	PUNCT
dti-1334	292	3	driven	drive	VERB
dti-1334	292	4	computer	computer	NOUN
dti-1334	292	5	simulation	simulation	NOUN
dti-1334	292	6	of	of	ADP
dti-1334	292	7	human	human	ADJ
dti-1334	292	8	cancer	cancer	NOUN
dti-1334	292	9	cell	cell	NOUN
dti-1334	292	10	.	.	PUNCT
dti-1334	293	1	ann	ann	PROPN
dti-1334	293	2	.	.	PUNCT
dti-1334	293	3	n.	n.	PROPN
dti-1334	293	4	y.	y.	PROPN
dti-1334	293	5	acad	acad	PROPN
dti-1334	293	6	.	.	PUNCT
dti-1334	294	1	sci	sci	PROPN
dti-1334	294	2	.	.	PROPN
dti-1334	294	3	,	,	PUNCT
dti-1334	294	4	1020:132–53	1020:132–53	NUM
dti-1334	294	5	.	.	PUNCT
dti-1334	295	1	64	64	NUM
dti-1334	295	2	shen	shen	NOUN
dti-1334	295	3	et	et	PROPN
dti-1334	295	4	al	al	PROPN
dti-1334	295	5	drug	drug	PROPN
dti-1334	295	6	target	target	NOUN
dti-1334	295	7	insights	insight	NOUN
dti-1334	295	8	2008:3	2008:3	NUM
dti-1334	295	9	ciordia	ciordia	NOUN
dti-1334	295	10	,	,	PUNCT
dti-1334	295	11	s.	s.	PROPN
dti-1334	295	12	,	,	PUNCT
dti-1334	295	13	de	de	PROPN
dti-1334	295	14	los	los	PROPN
dti-1334	295	15	rios	rios	PROPN
dti-1334	295	16	,	,	PUNCT
dti-1334	295	17	v.	v.	CCONJ
dti-1334	295	18	and	and	CCONJ
dti-1334	295	19	albar	albar	PROPN
dti-1334	295	20	,	,	PUNCT
dti-1334	295	21	j.p	j.p	PROPN
dti-1334	295	22	.	.	PROPN
dti-1334	295	23	2006	2006	NUM
dti-1334	295	24	.	.	PUNCT
dti-1334	296	1	contributions	contribution	NOUN
dti-1334	296	2	of	of	ADP
dti-1334	296	3	advanced	advanced	ADJ
dti-1334	296	4	proteomics	proteomic	NOUN
dti-1334	296	5	technologies	technology	NOUN
dti-1334	296	6	to	to	ADP
dti-1334	296	7	cancer	cancer	NOUN
dti-1334	296	8	diagnosis	diagnosis	NOUN
dti-1334	296	9	.	.	PUNCT
dti-1334	297	1	clin	clin	PROPN
dti-1334	297	2	.	.	PUNCT
dti-1334	298	1	transl	transl	PROPN
dti-1334	298	2	.	.	PUNCT
dti-1334	299	1	oncol	oncol	PROPN
dti-1334	299	2	.	.	PUNCT
dti-1334	299	3	,	,	PUNCT
dti-1334	300	1	8:566–80	8:566–80	PROPN
dti-1334	300	2	.	.	PUNCT
dti-1334	301	1	clarke	clarke	PROPN
dti-1334	301	2	,	,	PUNCT
dti-1334	301	3	w.	w.	PROPN
dti-1334	301	4	and	and	CCONJ
dti-1334	301	5	chan	chan	PROPN
dti-1334	301	6	,	,	PUNCT
dti-1334	301	7	d.w	d.w	PROPN
dti-1334	301	8	.	.	PROPN
dti-1334	301	9	2005	2005	NUM
dti-1334	301	10	.	.	PUNCT
dti-1334	302	1	proteinchips	proteinchip	NOUN
dti-1334	302	2	:	:	PUNCT
dti-1334	302	3	the	the	DET
dti-1334	302	4	essential	essential	ADJ
dti-1334	302	5	tools	tool	NOUN
dti-1334	302	6	for	for	ADP
dti-1334	302	7	proteomic	proteomic	ADJ
dti-1334	302	8	biomarker	biomarker	NOUN
dti-1334	302	9	discovery	discovery	NOUN
dti-1334	302	10	and	and	CCONJ
dti-1334	302	11	future	future	ADJ
dti-1334	302	12	clinical	clinical	ADJ
dti-1334	302	13	diagnostics	diagnostic	NOUN
dti-1334	302	14	.	.	PUNCT
dti-1334	303	1	clin	clin	PROPN
dti-1334	303	2	.	.	PUNCT
dti-1334	304	1	chem	chem	PROPN
dti-1334	304	2	.	.	PUNCT
dti-1334	305	1	lab	lab	PROPN
dti-1334	305	2	med	med	PROPN
dti-1334	305	3	.	.	PROPN
dti-1334	305	4	,	,	PUNCT
dti-1334	305	5	43:1279–80	43:1279–80	PROPN
dti-1334	305	6	.	.	PUNCT
dti-1334	306	1	collett	collett	PROPN
dti-1334	306	2	,	,	PUNCT
dti-1334	306	3	j.r	j.r	PROPN
dti-1334	306	4	.	.	PROPN
dti-1334	306	5	,	,	PUNCT
dti-1334	306	6	cho	cho	PROPN
dti-1334	306	7	,	,	PUNCT
dti-1334	306	8	e.j	e.j	PROPN
dti-1334	306	9	.	.	PROPN
dti-1334	306	10	and	and	CCONJ
dti-1334	306	11	ellington	ellington	PROPN
dti-1334	306	12	,	,	PUNCT
dti-1334	306	13	a.d	a.d	PROPN
dti-1334	306	14	.	.	PROPN
dti-1334	306	15	2005	2005	NUM
dti-1334	306	16	.	.	PUNCT
dti-1334	307	1	production	production	NOUN
dti-1334	307	2	and	and	CCONJ
dti-1334	307	3	processing	processing	NOUN
dti-1334	307	4	of	of	ADP
dti-1334	307	5	aptamer	aptamer	PROPN
dti-1334	307	6	microarrays	microarray	NOUN
dti-1334	307	7	.	.	PUNCT
dti-1334	308	1	methods	method	NOUN
dti-1334	308	2	,	,	PUNCT
dti-1334	308	3	37:4–15	37:4–15	PROPN
dti-1334	308	4	.	.	PUNCT
dti-1334	309	1	demir	demir	PROPN
dti-1334	309	2	,	,	PUNCT
dti-1334	309	3	e.	e.	PROPN
dti-1334	309	4	,	,	PUNCT
dti-1334	309	5	babur	babur	PROPN
dti-1334	309	6	,	,	PUNCT
dti-1334	309	7	o.	o.	PROPN
dti-1334	309	8	,	,	PUNCT
dti-1334	309	9	dogrusoz	dogrusoz	PROPN
dti-1334	309	10	,	,	PUNCT
dti-1334	309	11	u.	u.	NOUN
dti-1334	309	12	,	,	PUNCT
dti-1334	309	13	gursoy	gursoy	ADJ
dti-1334	309	14	,	,	PUNCT
dti-1334	309	15	a.	a.	NOUN
dti-1334	309	16	,	,	PUNCT
dti-1334	309	17	nisanci	nisanci	PROPN
dti-1334	309	18	,	,	PUNCT
dti-1334	309	19	g.	g.	PROPN
dti-1334	309	20	,	,	PUNCT
dti-1334	309	21	cetin	cetin	NOUN
dti-1334	309	22	-	-	PUNCT
dti-1334	309	23	atalay	atalay	NOUN
dti-1334	309	24	,	,	PUNCT
dti-1334	309	25	r.	r.	PROPN
dti-1334	309	26	and	and	CCONJ
dti-1334	309	27	ozturk	ozturk	PROPN
dti-1334	309	28	,	,	PUNCT
dti-1334	309	29	m.	m.	NOUN
dti-1334	309	30	2002	2002	NUM
dti-1334	309	31	.	.	PUNCT
dti-1334	310	1	patika	patika	NOUN
dti-1334	310	2	:	:	PUNCT
dti-1334	310	3	an	an	DET
dti-1334	310	4	integrated	integrate	VERB
dti-1334	310	5	visual	visual	ADJ
dti-1334	310	6	environment	environment	NOUN
dti-1334	310	7	for	for	ADP
dti-1334	310	8	collaborative	collaborative	ADJ
dti-1334	310	9	construction	construction	NOUN
dti-1334	310	10	and	and	CCONJ
dti-1334	310	11	analysis	analysis	NOUN
dti-1334	310	12	of	of	ADP
dti-1334	310	13	cellular	cellular	ADJ
dti-1334	310	14	pathways	pathway	NOUN
dti-1334	310	15	.	.	PUNCT
dti-1334	311	1	bioinformatics	bioinformatic	NOUN
dti-1334	311	2	,	,	PUNCT
dti-1334	311	3	18:996–1003	18:996–1003	NUM
dti-1334	311	4	.	.	NOUN
dti-1334	311	5	deutsch	deutsch	PROPN
dti-1334	311	6	,	,	PUNCT
dti-1334	311	7	e.w	e.w	PROPN
dti-1334	311	8	.	.	PROPN
dti-1334	311	9	,	,	PUNCT
dti-1334	311	10	lam	lam	PROPN
dti-1334	311	11	,	,	PUNCT
dti-1334	311	12	h.	h.	PROPN
dti-1334	311	13	and	and	CCONJ
dti-1334	311	14	aebersold	aebersold	PROPN
dti-1334	311	15	,	,	PUNCT
dti-1334	311	16	r.	r.	PROPN
dti-1334	311	17	2008	2008	NUM
dti-1334	311	18	.	.	PUNCT
dti-1334	312	1	data	datum	NOUN
dti-1334	312	2	analysis	analysis	NOUN
dti-1334	312	3	and	and	CCONJ
dti-1334	312	4	bioinformatics	bioinformatics	NOUN
dti-1334	312	5	tools	tool	NOUN
dti-1334	312	6	for	for	ADP
dti-1334	312	7	tandem	tandem	PROPN
dti-1334	312	8	mass	mass	ADJ
dti-1334	312	9	spectrometry	spectrometry	NOUN
dti-1334	312	10	in	in	ADP
dti-1334	312	11	proteomics	proteomic	NOUN
dti-1334	312	12	.	.	PUNCT
dti-1334	313	1	physiol	physiol	PROPN
dti-1334	313	2	.	.	PUNCT
dti-1334	314	1	genomics	genomic	NOUN
dti-1334	314	2	.	.	PUNCT
dti-1334	315	1	dickins	dickin	NOUN
dti-1334	315	2	,	,	PUNCT
dti-1334	315	3	r.a	r.a	PROPN
dti-1334	315	4	.	.	PROPN
dti-1334	315	5	,	,	PUNCT
dti-1334	315	6	hemann	hemann	PROPN
dti-1334	315	7	,	,	PUNCT
dti-1334	315	8	m.t	m.t	PROPN
dti-1334	315	9	.	.	PROPN
dti-1334	315	10	,	,	PUNCT
dti-1334	315	11	zilfou	zilfou	PROPN
dti-1334	315	12	,	,	PUNCT
dti-1334	315	13	j.t	j.t	PROPN
dti-1334	315	14	.	.	PROPN
dti-1334	315	15	,	,	PUNCT
dti-1334	315	16	simpson	simpson	PROPN
dti-1334	315	17	,	,	PUNCT
dti-1334	315	18	d.r	d.r	PROPN
dti-1334	315	19	.	.	PROPN
dti-1334	315	20	,	,	PUNCT
dti-1334	315	21	ibarra	ibarra	PROPN
dti-1334	315	22	,	,	PUNCT
dti-1334	315	23	i.	i.	PROPN
dti-1334	315	24	,	,	PUNCT
dti-1334	315	25	hannon	hannon	PROPN
dti-1334	315	26	,	,	PUNCT
dti-1334	315	27	g.j	g.j	PROPN
dti-1334	315	28	.	.	PROPN
dti-1334	315	29	and	and	CCONJ
dti-1334	315	30	lowe	lowe	PROPN
dti-1334	315	31	,	,	PUNCT
dti-1334	315	32	s.w	s.w	PROPN
dti-1334	315	33	.	.	PROPN
dti-1334	315	34	2005	2005	NUM
dti-1334	315	35	.	.	PUNCT
dti-1334	316	1	probing	probe	VERB
dti-1334	316	2	tumor	tumor	NOUN
dti-1334	316	3	phenotypes	phenotype	NOUN
dti-1334	316	4	using	use	VERB
dti-1334	316	5	stable	stable	ADJ
dti-1334	316	6	and	and	CCONJ
dti-1334	316	7	regulated	regulated	ADJ
dti-1334	316	8	synthetic	synthetic	ADJ
dti-1334	316	9	microrna	microrna	PROPN
dti-1334	316	10	precursors	precursor	NOUN
dti-1334	316	11	.	.	PUNCT
dti-1334	317	1	nat	nat	PROPN
dti-1334	317	2	.	.	PUNCT
dti-1334	318	1	genet	genet	PROPN
dti-1334	318	2	.	.	PUNCT
dti-1334	318	3	,	,	PUNCT
dti-1334	319	1	37:1289–95	37:1289–95	NUM
dti-1334	319	2	.	.	PUNCT
dti-1334	320	1	duan	duan	PROPN
dti-1334	320	2	,	,	PUNCT
dti-1334	320	3	x.j	x.j	PROPN
dti-1334	320	4	.	.	PROPN
dti-1334	320	5	,	,	PUNCT
dti-1334	320	6	xenarios	xenarios	PROPN
dti-1334	320	7	,	,	PUNCT
dti-1334	320	8	i.	i.	NOUN
dti-1334	320	9	and	and	CCONJ
dti-1334	320	10	eisenberg	eisenberg	PROPN
dti-1334	320	11	,	,	PUNCT
dti-1334	320	12	d.	d.	PROPN
dti-1334	320	13	2002	2002	NUM
dti-1334	320	14	.	.	PUNCT
dti-1334	321	1	describing	describe	VERB
dti-1334	321	2	biological	biological	ADJ
dti-1334	321	3	protein	protein	NOUN
dti-1334	321	4	interactions	interaction	NOUN
dti-1334	321	5	in	in	ADP
dti-1334	321	6	terms	term	NOUN
dti-1334	321	7	of	of	ADP
dti-1334	321	8	protein	protein	NOUN
dti-1334	321	9	states	state	NOUN
dti-1334	321	10	and	and	CCONJ
dti-1334	321	11	state	state	NOUN
dti-1334	321	12	transitions	transition	NOUN
dti-1334	321	13	:	:	PUNCT
dti-1334	321	14	the	the	DET
dti-1334	321	15	livedip	livedip	ADJ
dti-1334	321	16	database	database	NOUN
dti-1334	321	17	.	.	PUNCT
dti-1334	321	18	mol	mol	PROPN
dti-1334	321	19	.	.	PROPN
dti-1334	321	20	cell	cell	NOUN
dti-1334	321	21	.	.	PUNCT
dti-1334	322	1	proteomics	proteomic	NOUN
dti-1334	322	2	,	,	PUNCT
dti-1334	322	3	1:104–16	1:104–16	NUM
dti-1334	322	4	.	.	PUNCT
dti-1334	322	5	emmert	emmert	NOUN
dti-1334	322	6	-	-	PUNCT
dti-1334	322	7	buck	buck	NOUN
dti-1334	322	8	,	,	PUNCT
dti-1334	322	9	m.r	m.r	PROPN
dti-1334	322	10	.	.	PROPN
dti-1334	322	11	,	,	PUNCT
dti-1334	322	12	bonner	bonner	PROPN
dti-1334	322	13	,	,	PUNCT
dti-1334	322	14	r.f	r.f	PROPN
dti-1334	322	15	.	.	PROPN
dti-1334	322	16	,	,	PUNCT
dti-1334	322	17	smith	smith	PROPN
dti-1334	322	18	,	,	PUNCT
dti-1334	322	19	p.d	p.d	PROPN
dti-1334	322	20	.	.	PROPN
dti-1334	322	21	,	,	PUNCT
dti-1334	322	22	chuaqui	chuaqui	PROPN
dti-1334	322	23	,	,	PUNCT
dti-1334	322	24	r.f	r.f	PROPN
dti-1334	322	25	.	.	PROPN
dti-1334	322	26	,	,	PUNCT
dti-1334	322	27	zhuang	zhuang	PROPN
dti-1334	322	28	,	,	PUNCT
dti-1334	322	29	z.	z.	PROPN
dti-1334	322	30	,	,	PUNCT
dti-1334	322	31	goldstein	goldstein	PROPN
dti-1334	322	32	,	,	PUNCT
dti-1334	322	33	s.r	s.r	PROPN
dti-1334	322	34	.	.	PROPN
dti-1334	322	35	,	,	PUNCT
dti-1334	322	36	weiss	weiss	PROPN
dti-1334	322	37	,	,	PUNCT
dti-1334	322	38	r.a	r.a	PROPN
dti-1334	322	39	.	.	PROPN
dti-1334	322	40	and	and	CCONJ
dti-1334	322	41	liotta	liotta	PROPN
dti-1334	322	42	,	,	PUNCT
dti-1334	322	43	l.a	l.a	PROPN
dti-1334	322	44	.	.	PROPN
dti-1334	322	45	1996	1996	NUM
dti-1334	322	46	.	.	PUNCT
dti-1334	323	1	laser	laser	NOUN
dti-1334	323	2	capture	capture	NOUN
dti-1334	323	3	microdissection	microdissection	NOUN
dti-1334	323	4	.	.	PUNCT
dti-1334	324	1	science	science	NOUN
dti-1334	324	2	,	,	PUNCT
dti-1334	324	3	274:998–1001	274:998–1001	NUM
dti-1334	324	4	.	.	PUNCT
dti-1334	324	5	emmert	emmert	NOUN
dti-1334	324	6	-	-	PUNCT
dti-1334	324	7	buck	buck	NOUN
dti-1334	324	8	,	,	PUNCT
dti-1334	324	9	m.r	m.r	PROPN
dti-1334	324	10	.	.	PROPN
dti-1334	324	11	,	,	PUNCT
dti-1334	324	12	roth	roth	PROPN
dti-1334	324	13	,	,	PUNCT
dti-1334	324	14	m.j	m.j	PROPN
dti-1334	324	15	.	.	PROPN
dti-1334	324	16	,	,	PUNCT
dti-1334	324	17	zhuang	zhuang	PROPN
dti-1334	324	18	,	,	PUNCT
dti-1334	324	19	z.	z.	PROPN
dti-1334	324	20	,	,	PUNCT
dti-1334	324	21	campo	campo	PROPN
dti-1334	324	22	,	,	PUNCT
dti-1334	324	23	e.	e.	PROPN
dti-1334	324	24	,	,	PUNCT
dti-1334	324	25	rozhin	rozhin	PROPN
dti-1334	324	26	,	,	PUNCT
dti-1334	324	27	j.	j.	PROPN
dti-1334	324	28	,	,	PUNCT
dti-1334	324	29	sloane	sloane	PROPN
dti-1334	324	30	,	,	PUNCT
dti-1334	324	31	b.f	b.f	PROPN
dti-1334	324	32	.	.	PROPN
dti-1334	324	33	,	,	PUNCT
dti-1334	324	34	liotta	liotta	PROPN
dti-1334	324	35	,	,	PUNCT
dti-1334	324	36	l.a	l.a	PROPN
dti-1334	324	37	.	.	PROPN
dti-1334	324	38	and	and	CCONJ
dti-1334	324	39	stetler	stetler	NOUN
dti-1334	324	40	-	-	PUNCT
dti-1334	324	41	stevenson	stevenson	PROPN
dti-1334	324	42	,	,	PUNCT
dti-1334	324	43	w.g	w.g	PROPN
dti-1334	324	44	.	.	PROPN
dti-1334	324	45	1994	1994	NUM
dti-1334	324	46	.	.	PUNCT
dti-1334	325	1	increased	increase	VERB
dti-1334	325	2	gelatinase	gelatinase	PROPN
dti-1334	325	3	a	a	DET
dti-1334	325	4	(	(	PUNCT
dti-1334	325	5	mmp-2	mmp-2	NUM
dti-1334	325	6	)	)	PUNCT
dti-1334	325	7	and	and	CCONJ
dti-1334	325	8	cathepsin	cathepsin	PROPN
dti-1334	325	9	b.	b.	PROPN
dti-1334	325	10	activity	activity	NOUN
dti-1334	325	11	in	in	ADP
dti-1334	325	12	invasive	invasive	ADJ
dti-1334	325	13	tumor	tumor	NOUN
dti-1334	325	14	regions	region	NOUN
dti-1334	325	15	of	of	ADP
dti-1334	325	16	human	human	ADJ
dti-1334	325	17	colon	colon	NOUN
dti-1334	325	18	cancer	cancer	NOUN
dti-1334	325	19	samples	sample	NOUN
dti-1334	325	20	.	.	PUNCT
dti-1334	326	1	am	be	AUX
dti-1334	326	2	.	.	PUNCT
dti-1334	327	1	j.	j.	PROPN
dti-1334	327	2	pathol	pathol	PROPN
dti-1334	327	3	.	.	PROPN
dti-1334	327	4	,	,	PUNCT
dti-1334	327	5	145:1285–90	145:1285–90	NUM
dti-1334	327	6	.	.	PUNCT
dti-1334	328	1	feldman	feldman	PROPN
dti-1334	328	2	,	,	PUNCT
dti-1334	328	3	a.l	a.l	PROPN
dti-1334	328	4	.	.	PROPN
dti-1334	328	5	,	,	PUNCT
dti-1334	328	6	espina	espina	PROPN
dti-1334	328	7	,	,	PUNCT
dti-1334	328	8	v.	v.	ADV
dti-1334	328	9	,	,	PUNCT
dti-1334	328	10	petricoin	petricoin	PROPN
dti-1334	328	11	,	,	PUNCT
dti-1334	328	12	e.f	e.f	PROPN
dti-1334	328	13	.	.	PROPN
dti-1334	328	14	,	,	PUNCT
dti-1334	328	15	liotta	liotta	PROPN
dti-1334	328	16	,	,	PUNCT
dti-1334	328	17	l.a	l.a	PROPN
dti-1334	328	18	.	.	PROPN
dti-1334	328	19	and	and	CCONJ
dti-1334	328	20	rosenblatt	rosenblatt	PROPN
dti-1334	328	21	,	,	PUNCT
dti-1334	328	22	k.p	k.p	PROPN
dti-1334	328	23	.	.	PROPN
dti-1334	328	24	2004	2004	NUM
dti-1334	328	25	.	.	PUNCT
dti-1334	329	1	use	use	NOUN
dti-1334	329	2	of	of	ADP
dti-1334	329	3	proteomic	proteomic	ADJ
dti-1334	329	4	patterns	pattern	NOUN
dti-1334	329	5	to	to	PART
dti-1334	329	6	screen	screen	VERB
dti-1334	329	7	for	for	ADP
dti-1334	329	8	gastrointestinal	gastrointestinal	ADJ
dti-1334	329	9	malignancies	malignancy	NOUN
dti-1334	329	10	.	.	PUNCT
dti-1334	330	1	surgery	surgery	NOUN
dti-1334	330	2	,	,	PUNCT
dti-1334	330	3	135:243–7	135:243–7	NUM
dti-1334	330	4	.	.	PUNCT
dti-1334	330	5	ferre	ferre	PROPN
dti-1334	330	6	,	,	PUNCT
dti-1334	330	7	f.	f.	PROPN
dti-1334	330	8	2005	2005	NUM
dti-1334	330	9	.	.	PUNCT
dti-1334	331	1	integrated	integrate	VERB
dti-1334	331	2	bioinformatics	bioinformatics	NOUN
dti-1334	331	3	software	software	NOUN
dti-1334	331	4	at	at	ADP
dti-1334	331	5	ncbi	ncbi	NOUN
dti-1334	331	6	,	,	PUNCT
dti-1334	331	7	encyclopedia	encyclopedia	NOUN
dti-1334	331	8	of	of	ADP
dti-1334	331	9	genetics	genetic	NOUN
dti-1334	331	10	,	,	PUNCT
dti-1334	331	11	genomics	genomics	NOUN
dti-1334	331	12	,	,	PUNCT
dti-1334	331	13	proteomics	proteomic	NOUN
dti-1334	331	14	and	and	CCONJ
dti-1334	331	15	bioinformatics	bioinformatics	NOUN
dti-1334	331	16	.	.	PUNCT
dti-1334	332	1	part	part	NOUN
dti-1334	332	2	4	4	NUM
dti-1334	332	3	—	—	PUNCT
dti-1334	332	4	bioinformatics	bioinformatics	NOUN
dti-1334	332	5	.	.	PUNCT
dti-1334	333	1	john	john	PROPN
dti-1334	333	2	wiley	wiley	PROPN
dti-1334	333	3	and	and	CCONJ
dti-1334	333	4	sons	son	NOUN
dti-1334	333	5	,	,	PUNCT
dti-1334	333	6	ltd	ltd	PROPN
dti-1334	333	7	.	.	PROPN
dti-1334	333	8	florens	floren	NOUN
dti-1334	333	9	,	,	PUNCT
dti-1334	333	10	l.	l.	NOUN
dti-1334	333	11	and	and	CCONJ
dti-1334	333	12	washburn	washburn	PROPN
dti-1334	333	13	,	,	PUNCT
dti-1334	333	14	m.p	m.p	PROPN
dti-1334	333	15	.	.	PROPN
dti-1334	333	16	2006	2006	NUM
dti-1334	333	17	.	.	PUNCT
dti-1334	334	1	proteomic	proteomic	ADJ
dti-1334	334	2	analysis	analysis	NOUN
dti-1334	334	3	by	by	ADP
dti-1334	334	4	multidimensional	multidimensional	ADJ
dti-1334	334	5	protein	protein	NOUN
dti-1334	334	6	identifi	identifi	PROPN
dti-1334	334	7	cation	cation	NOUN
dti-1334	334	8	technology	technology	NOUN
dti-1334	334	9	.	.	PUNCT
dti-1334	335	1	methods	method	NOUN
dti-1334	335	2	mol	mol	PROPN
dti-1334	335	3	.	.	PUNCT
dti-1334	336	1	biol	biol	PROPN
dti-1334	336	2	.	.	PUNCT
dti-1334	336	3	,	,	PUNCT
dti-1334	337	1	328:159–75	328:159–75	NUM
dti-1334	337	2	.	.	PUNCT
dti-1334	338	1	friedman	friedman	PROPN
dti-1334	338	2	,	,	PUNCT
dti-1334	338	3	d.b	d.b	PROPN
dti-1334	338	4	.	.	PROPN
dti-1334	338	5	2007	2007	NUM
dti-1334	338	6	.	.	PUNCT
dti-1334	339	1	quantitative	quantitative	ADJ
dti-1334	339	2	proteomics	proteomic	NOUN
dti-1334	339	3	for	for	ADP
dti-1334	339	4	two	two	NUM
dti-1334	339	5	-	-	PUNCT
dti-1334	339	6	dimensional	dimensional	ADJ
dti-1334	339	7	gels	gel	NOUN
dti-1334	339	8	using	use	VERB
dti-1334	339	9	difference	difference	NOUN
dti-1334	339	10	gel	gel	NOUN
dti-1334	339	11	electrophoresis	electrophoresis	NOUN
dti-1334	339	12	.	.	PUNCT
dti-1334	340	1	methods	method	NOUN
dti-1334	340	2	mol	mol	PROPN
dti-1334	340	3	.	.	PUNCT
dti-1334	341	1	biol	biol	PROPN
dti-1334	341	2	.	.	PUNCT
dti-1334	341	3	,	,	PUNCT
dti-1334	342	1	367:219–39	367:219–39	PROPN
dti-1334	342	2	.	.	PUNCT
dti-1334	343	1	friedman	friedman	PROPN
dti-1334	343	2	,	,	PUNCT
dti-1334	343	3	d.b	d.b	PROPN
dti-1334	343	4	.	.	PROPN
dti-1334	343	5	,	,	PUNCT
dti-1334	343	6	hill	hill	PROPN
dti-1334	343	7	,	,	PUNCT
dti-1334	343	8	s.	s.	PROPN
dti-1334	343	9	,	,	PUNCT
dti-1334	343	10	keller	keller	PROPN
dti-1334	343	11	,	,	PUNCT
dti-1334	343	12	j.w	j.w	PROPN
dti-1334	343	13	.	.	PROPN
dti-1334	343	14	,	,	PUNCT
dti-1334	343	15	merchant	merchant	NOUN
dti-1334	343	16	,	,	PUNCT
dti-1334	343	17	n.b	n.b	PROPN
dti-1334	343	18	.	.	PROPN
dti-1334	343	19	,	,	PUNCT
dti-1334	343	20	levy	levy	NOUN
dti-1334	343	21	,	,	PUNCT
dti-1334	343	22	s.e	s.e	PROPN
dti-1334	343	23	.	.	PROPN
dti-1334	343	24	,	,	PUNCT
dti-1334	343	25	coffey	coffey	PROPN
dti-1334	343	26	,	,	PUNCT
dti-1334	343	27	r.j	r.j	PROPN
dti-1334	343	28	.	.	PROPN
dti-1334	343	29	and	and	CCONJ
dti-1334	343	30	caprioli	caprioli	PROPN
dti-1334	343	31	,	,	PUNCT
dti-1334	343	32	r.m	r.m	PROPN
dti-1334	343	33	.	.	PROPN
dti-1334	343	34	2004	2004	NUM
dti-1334	343	35	.	.	PUNCT
dti-1334	344	1	proteome	proteome	ADJ
dti-1334	344	2	analysis	analysis	NOUN
dti-1334	344	3	of	of	ADP
dti-1334	344	4	human	human	ADJ
dti-1334	344	5	colon	colon	NOUN
dti-1334	344	6	cancer	cancer	NOUN
dti-1334	344	7	by	by	ADP
dti-1334	344	8	two	two	NUM
dti-1334	344	9	-	-	PUNCT
dti-1334	344	10	dimensional	dimensional	ADJ
dti-1334	344	11	difference	difference	NOUN
dti-1334	344	12	gel	gel	NOUN
dti-1334	344	13	electrophoresis	electrophoresis	NOUN
dti-1334	344	14	and	and	CCONJ
dti-1334	344	15	mass	mass	ADJ
dti-1334	344	16	spectrometry	spectrometry	NOUN
dti-1334	344	17	.	.	PUNCT
dti-1334	345	1	proteomics	proteomic	NOUN
dti-1334	345	2	,	,	PUNCT
dti-1334	345	3	4:793–811	4:793–811	PRON
dti-1334	345	4	.	.	PUNCT
dti-1334	346	1	gafken	gafken	VERB
dti-1334	346	2	,	,	PUNCT
dti-1334	346	3	p.r	p.r	PROPN
dti-1334	346	4	.	.	PROPN
dti-1334	346	5	and	and	CCONJ
dti-1334	346	6	lampe	lampe	PROPN
dti-1334	346	7	,	,	PUNCT
dti-1334	346	8	p.d	p.d	PROPN
dti-1334	346	9	.	.	PROPN
dti-1334	346	10	2006	2006	NUM
dti-1334	346	11	.	.	PUNCT
dti-1334	347	1	methodologies	methodology	NOUN
dti-1334	347	2	for	for	ADP
dti-1334	347	3	characterizing	characterize	VERB
dti-1334	347	4	phosphoproteins	phosphoprotein	NOUN
dti-1334	347	5	by	by	ADP
dti-1334	347	6	mass	mass	ADJ
dti-1334	347	7	spectrometry	spectrometry	NOUN
dti-1334	347	8	.	.	PUNCT
dti-1334	348	1	cell	cell	NOUN
dti-1334	348	2	.	.	PUNCT
dti-1334	349	1	commun	commun	PROPN
dti-1334	349	2	.	.	PUNCT
dti-1334	350	1	adhes	adhe	NOUN
dti-1334	350	2	,	,	PUNCT
dti-1334	350	3	13:249–62	13:249–62	NUM
dti-1334	350	4	.	.	PUNCT
dti-1334	351	1	garber	garber	PROPN
dti-1334	351	2	,	,	PUNCT
dti-1334	351	3	m.e	m.e	PROPN
dti-1334	351	4	.	.	PROPN
dti-1334	351	5	,	,	PUNCT
dti-1334	351	6	troyanskaya	troyanskaya	PROPN
dti-1334	351	7	,	,	PUNCT
dti-1334	351	8	o.g	o.g	PROPN
dti-1334	351	9	.	.	PROPN
dti-1334	351	10	,	,	PUNCT
dti-1334	351	11	schluens	schluens	PROPN
dti-1334	351	12	,	,	PUNCT
dti-1334	351	13	k.	k.	PROPN
dti-1334	351	14	,	,	PUNCT
dti-1334	351	15	petersen	petersen	PROPN
dti-1334	351	16	,	,	PUNCT
dti-1334	351	17	s.	s.	PROPN
dti-1334	351	18	,	,	PUNCT
dti-1334	351	19	thaesler	thaesler	PROPN
dti-1334	351	20	,	,	PUNCT
dti-1334	351	21	z.	z.	PROPN
dti-1334	351	22	,	,	PUNCT
dti-1334	351	23	pacyna	pacyna	NOUN
dti-1334	351	24	-	-	PUNCT
dti-1334	351	25	gengelbach	gengelbach	NOUN
dti-1334	351	26	,	,	PUNCT
dti-1334	351	27	m.	m.	NOUN
dti-1334	351	28	,	,	PUNCT
dti-1334	351	29	van	van	PROPN
dti-1334	351	30	de	de	PROPN
dti-1334	351	31	rijn	rijn	PROPN
dti-1334	351	32	,	,	PUNCT
dti-1334	351	33	m.	m.	NOUN
dti-1334	351	34	,	,	PUNCT
dti-1334	351	35	rosen	rosen	PROPN
dti-1334	351	36	,	,	PUNCT
dti-1334	351	37	g.d	g.d	PROPN
dti-1334	351	38	.	.	PROPN
dti-1334	351	39	,	,	PUNCT
dti-1334	351	40	perou	perou	NOUN
dti-1334	351	41	,	,	PUNCT
dti-1334	351	42	c.m	c.m	PROPN
dti-1334	351	43	.	.	PROPN
dti-1334	351	44	,	,	PUNCT
dti-1334	351	45	whyte	whyte	PROPN
dti-1334	351	46	,	,	PUNCT
dti-1334	351	47	r.i	r.i	PROPN
dti-1334	351	48	.	.	PROPN
dti-1334	351	49	,	,	PUNCT
dti-1334	351	50	altman	altman	PROPN
dti-1334	351	51	,	,	PUNCT
dti-1334	351	52	r.b	r.b	PROPN
dti-1334	351	53	.	.	PROPN
dti-1334	351	54	,	,	PUNCT
dti-1334	351	55	brown	brown	PROPN
dti-1334	351	56	,	,	PUNCT
dti-1334	351	57	p.o	p.o	PROPN
dti-1334	351	58	.	.	PROPN
dti-1334	351	59	,	,	PUNCT
dti-1334	351	60	botstein	botstein	PROPN
dti-1334	351	61	,	,	PUNCT
dti-1334	351	62	d.	d.	PROPN
dti-1334	351	63	and	and	CCONJ
dti-1334	351	64	petersen	petersen	PROPN
dti-1334	351	65	,	,	PUNCT
dti-1334	351	66	i.	i.	PROPN
dti-1334	351	67	2001	2001	NUM
dti-1334	351	68	.	.	PUNCT
dti-1334	352	1	diversity	diversity	NOUN
dti-1334	352	2	of	of	ADP
dti-1334	352	3	gene	gene	NOUN
dti-1334	352	4	expression	expression	NOUN
dti-1334	352	5	in	in	ADP
dti-1334	352	6	adenocarcinoma	adenocarcinoma	NOUN
dti-1334	352	7	of	of	ADP
dti-1334	352	8	the	the	DET
dti-1334	352	9	lung	lung	PROPN
dti-1334	352	10	.	.	PUNCT
dti-1334	353	1	proc	proc	PROPN
dti-1334	353	2	.	.	PUNCT
dti-1334	354	1	natl	natl	PROPN
dti-1334	354	2	.	.	PUNCT
dti-1334	355	1	acad	acad	PROPN
dti-1334	355	2	.	.	PUNCT
dti-1334	356	1	sci	sci	PROPN
dti-1334	356	2	.	.	PUNCT
dti-1334	356	3	u.s.a	u.s.a	PROPN
dti-1334	356	4	.	.	PROPN
dti-1334	356	5	,	,	PUNCT
dti-1334	356	6	98:13784–9	98:13784–9	X
dti-1334	356	7	.	.	PUNCT
dti-1334	357	1	gossen	gossen	PROPN
dti-1334	357	2	,	,	PUNCT
dti-1334	357	3	m.	m.	NOUN
dti-1334	357	4	and	and	CCONJ
dti-1334	357	5	bujard	bujard	PROPN
dti-1334	357	6	,	,	PUNCT
dti-1334	357	7	h.	h.	PROPN
dti-1334	357	8	1992	1992	NUM
dti-1334	357	9	.	.	PUNCT
dti-1334	358	1	tight	tight	ADJ
dti-1334	358	2	control	control	NOUN
dti-1334	358	3	of	of	ADP
dti-1334	358	4	gene	gene	NOUN
dti-1334	358	5	expression	expression	NOUN
dti-1334	358	6	in	in	ADP
dti-1334	358	7	mammalian	mammalian	ADJ
dti-1334	358	8	cells	cell	NOUN
dti-1334	358	9	by	by	ADP
dti-1334	358	10	tetracycline	tetracycline	NOUN
dti-1334	358	11	-	-	PUNCT
dti-1334	358	12	responsive	responsive	ADJ
dti-1334	358	13	promoters	promoter	NOUN
dti-1334	358	14	.	.	PUNCT
dti-1334	359	1	proc	proc	PROPN
dti-1334	359	2	.	.	PUNCT
dti-1334	360	1	natl	natl	PROPN
dti-1334	360	2	.	.	PUNCT
dti-1334	361	1	acad	acad	PROPN
dti-1334	361	2	.	.	PUNCT
dti-1334	362	1	sci	sci	PROPN
dti-1334	362	2	.	.	PUNCT
dti-1334	362	3	u.s.a	u.s.a	PROPN
dti-1334	362	4	.	.	PROPN
dti-1334	362	5	,	,	PUNCT
dti-1334	362	6	89:5547–51	89:5547–51	X
dti-1334	362	7	.	.	PUNCT
dti-1334	363	1	griffi	griffi	NOUN
dti-1334	363	2	n	n	CCONJ
dti-1334	363	3	,	,	PUNCT
dti-1334	363	4	t.j	t.j	PROPN
dti-1334	363	5	.	.	PROPN
dti-1334	363	6	,	,	PUNCT
dti-1334	363	7	lock	lock	PROPN
dti-1334	363	8	,	,	PUNCT
dti-1334	363	9	c.m	c.m	PROPN
dti-1334	363	10	.	.	PROPN
dti-1334	363	11	,	,	PUNCT
dti-1334	363	12	li	li	PROPN
dti-1334	363	13	,	,	PUNCT
dti-1334	363	14	x.j	x.j	PROPN
dti-1334	363	15	.	.	PROPN
dti-1334	363	16	,	,	PUNCT
dti-1334	363	17	patel	patel	PROPN
dti-1334	363	18	,	,	PUNCT
dti-1334	363	19	a.	a.	PROPN
dti-1334	363	20	,	,	PUNCT
dti-1334	363	21	chervetsova	chervetsova	PROPN
dti-1334	363	22	,	,	PUNCT
dti-1334	363	23	i.	i.	PROPN
dti-1334	363	24	,	,	PUNCT
dti-1334	363	25	lee	lee	PROPN
dti-1334	363	26	,	,	PUNCT
dti-1334	363	27	h.	h.	PROPN
dti-1334	363	28	,	,	PUNCT
dti-1334	363	29	wright	wright	PROPN
dti-1334	363	30	,	,	PUNCT
dti-1334	363	31	m.e	m.e	PROPN
dti-1334	363	32	.	.	PROPN
dti-1334	363	33	,	,	PUNCT
dti-1334	363	34	ranish	ranish	PROPN
dti-1334	363	35	,	,	PUNCT
dti-1334	363	36	j.a	j.a	PROPN
dti-1334	363	37	.	.	PROPN
dti-1334	363	38	,	,	PUNCT
dti-1334	363	39	chen	chen	PROPN
dti-1334	363	40	,	,	PUNCT
dti-1334	363	41	s.s	s.s	PROPN
dti-1334	363	42	.	.	PROPN
dti-1334	363	43	and	and	CCONJ
dti-1334	363	44	aebersold	aebersold	PROPN
dti-1334	363	45	,	,	PUNCT
dti-1334	363	46	r.	r.	PROPN
dti-1334	363	47	2003	2003	NUM
dti-1334	363	48	.	.	PUNCT
dti-1334	364	1	abundance	abundance	NOUN
dti-1334	364	2	ratio	ratio	NOUN
dti-1334	364	3	-	-	PUNCT
dti-1334	364	4	dependent	dependent	ADJ
dti-1334	364	5	proteomic	proteomic	ADJ
dti-1334	364	6	analysis	analysis	NOUN
dti-1334	364	7	by	by	ADP
dti-1334	364	8	mass	mass	ADJ
dti-1334	364	9	spectrometry	spectrometry	NOUN
dti-1334	364	10	.	.	PUNCT
dti-1334	365	1	anal	anal	PROPN
dti-1334	365	2	.	.	PUNCT
dti-1334	365	3	chem	chem	PROPN
dti-1334	365	4	.	.	PUNCT
dti-1334	366	1	,	,	PUNCT
dti-1334	367	1	75:867–74	75:867–74	PROPN
dti-1334	367	2	.	.	PUNCT
dti-1334	368	1	grimm	grimm	PROPN
dti-1334	368	2	,	,	PUNCT
dti-1334	368	3	d.	d.	PROPN
dti-1334	368	4	and	and	CCONJ
dti-1334	368	5	kay	kay	PROPN
dti-1334	368	6	,	,	PUNCT
dti-1334	368	7	m.a	m.a	PROPN
dti-1334	368	8	.	.	PROPN
dti-1334	368	9	2006	2006	NUM
dti-1334	368	10	.	.	PUNCT
dti-1334	369	1	therapeutic	therapeutic	ADJ
dti-1334	369	2	short	short	ADJ
dti-1334	369	3	hairpin	hairpin	NOUN
dti-1334	369	4	rna	rna	NOUN
dti-1334	369	5	expression	expression	NOUN
dti-1334	369	6	in	in	ADP
dti-1334	369	7	the	the	DET
dti-1334	369	8	liver	liver	NOUN
dti-1334	369	9	:	:	PUNCT
dti-1334	369	10	viral	viral	ADJ
dti-1334	369	11	targets	target	NOUN
dti-1334	369	12	and	and	CCONJ
dti-1334	369	13	vectors	vector	NOUN
dti-1334	369	14	.	.	PUNCT
dti-1334	370	1	gene	gene	NOUN
dti-1334	370	2	ther	ther	ADV
dti-1334	370	3	.	.	PUNCT
dti-1334	370	4	,	,	PUNCT
dti-1334	370	5	13:563–75	13:563–75	PROPN
dti-1334	370	6	.	.	PUNCT
dti-1334	371	1	gu	gu	PROPN
dti-1334	371	2	,	,	PUNCT
dti-1334	371	3	j.	j.	PROPN
dti-1334	371	4	and	and	CCONJ
dti-1334	371	5	fang	fang	PROPN
dti-1334	371	6	,	,	PUNCT
dti-1334	371	7	b.	b.	PROPN
dti-1334	371	8	2003	2003	NUM
dti-1334	371	9	.	.	PUNCT
dti-1334	372	1	telomerase	telomerase	NOUN
dti-1334	372	2	promoter	promoter	NOUN
dti-1334	372	3	-	-	PUNCT
dti-1334	372	4	driven	drive	VERB
dti-1334	372	5	cancer	cancer	NOUN
dti-1334	372	6	gene	gene	NOUN
dti-1334	372	7	therapy	therapy	NOUN
dti-1334	372	8	.	.	PUNCT
dti-1334	373	1	cancer	cancer	NOUN
dti-1334	373	2	biol	biol	PROPN
dti-1334	373	3	.	.	PUNCT
dti-1334	374	1	ther	ther	ADV
dti-1334	374	2	.	.	PUNCT
dti-1334	374	3	,	,	PUNCT
dti-1334	374	4	2	2	NUM
dti-1334	374	5	:	:	PUNCT
dti-1334	374	6	s64–70	s64–70	PROPN
dti-1334	374	7	.	.	PUNCT
dti-1334	375	1	gupta	gupta	PROPN
dti-1334	375	2	,	,	PUNCT
dti-1334	375	3	s.	s.	PROPN
dti-1334	375	4	,	,	PUNCT
dti-1334	375	5	schoer	schoer	PROPN
dti-1334	375	6	,	,	PUNCT
dti-1334	375	7	r.a	r.a	PROPN
dti-1334	375	8	.	.	PROPN
dti-1334	375	9	,	,	PUNCT
dti-1334	375	10	egan	egan	PROPN
dti-1334	375	11	,	,	PUNCT
dti-1334	375	12	j.e	j.e	PROPN
dti-1334	375	13	.	.	PROPN
dti-1334	375	14	,	,	PUNCT
dti-1334	375	15	hannon	hannon	PROPN
dti-1334	375	16	,	,	PUNCT
dti-1334	375	17	g.j	g.j	PROPN
dti-1334	375	18	.	.	PROPN
dti-1334	375	19	and	and	CCONJ
dti-1334	375	20	mittal	mittal	PROPN
dti-1334	375	21	,	,	PUNCT
dti-1334	375	22	v.	v.	ADP
dti-1334	375	23	2004	2004	NUM
dti-1334	375	24	.	.	PUNCT
dti-1334	376	1	inducible	inducible	ADJ
dti-1334	376	2	,	,	PUNCT
dti-1334	376	3	reversible	reversible	ADJ
dti-1334	376	4	,	,	PUNCT
dti-1334	376	5	and	and	CCONJ
dti-1334	376	6	stable	stable	ADJ
dti-1334	376	7	rna	rna	NOUN
dti-1334	376	8	interference	interference	NOUN
dti-1334	376	9	in	in	ADP
dti-1334	376	10	mammalian	mammalian	ADJ
dti-1334	376	11	cells	cell	NOUN
dti-1334	376	12	.	.	PUNCT
dti-1334	377	1	proc	proc	NOUN
dti-1334	377	2	.	.	PUNCT
dti-1334	378	1	natl	natl	PROPN
dti-1334	378	2	.	.	PUNCT
dti-1334	379	1	acad	acad	PROPN
dti-1334	379	2	.	.	PUNCT
dti-1334	380	1	sci	sci	PROPN
dti-1334	380	2	.	.	PUNCT
dti-1334	380	3	u.s.a	u.s.a	PROPN
dti-1334	380	4	.	.	PROPN
dti-1334	380	5	,	,	PUNCT
dti-1334	381	1	101:1927–32	101:1927–32	X
dti-1334	381	2	.	.	PUNCT
dti-1334	382	1	gygi	gygi	PROPN
dti-1334	382	2	,	,	PUNCT
dti-1334	382	3	s.p	s.p	PROPN
dti-1334	382	4	.	.	PROPN
dti-1334	382	5	,	,	PUNCT
dti-1334	382	6	rist	rist	PROPN
dti-1334	382	7	,	,	PUNCT
dti-1334	382	8	b.	b.	PROPN
dti-1334	382	9	,	,	PUNCT
dti-1334	382	10	gerber	gerber	PROPN
dti-1334	382	11	,	,	PUNCT
dti-1334	382	12	s.a	s.a	PROPN
dti-1334	382	13	.	.	PROPN
dti-1334	382	14	,	,	PUNCT
dti-1334	382	15	turecek	turecek	PROPN
dti-1334	382	16	,	,	PUNCT
dti-1334	382	17	f.	f.	PROPN
dti-1334	382	18	,	,	PUNCT
dti-1334	382	19	gelb	gelb	PROPN
dti-1334	382	20	,	,	PUNCT
dti-1334	382	21	m.h	m.h	PROPN
dti-1334	382	22	.	.	PROPN
dti-1334	382	23	and	and	CCONJ
dti-1334	382	24	aebersold	aebersold	PROPN
dti-1334	382	25	,	,	PUNCT
dti-1334	382	26	r.	r.	PROPN
dti-1334	382	27	1999	1999	NUM
dti-1334	382	28	.	.	PUNCT
dti-1334	383	1	quantitative	quantitative	ADJ
dti-1334	383	2	analysis	analysis	NOUN
dti-1334	383	3	of	of	ADP
dti-1334	383	4	complex	complex	ADJ
dti-1334	383	5	protein	protein	NOUN
dti-1334	383	6	mixtures	mixture	NOUN
dti-1334	383	7	using	use	VERB
dti-1334	383	8	isotope	isotope	NOUN
dti-1334	383	9	-	-	PUNCT
dti-1334	383	10	coded	code	VERB
dti-1334	383	11	affi	affi	PROPN
dti-1334	383	12	nity	nity	NOUN
dti-1334	383	13	tags	tag	NOUN
dti-1334	383	14	.	.	PUNCT
dti-1334	384	1	nat	nat	NOUN
dti-1334	384	2	.	.	PUNCT
dti-1334	385	1	biotechnol	biotechnol	PROPN
dti-1334	385	2	.	.	PUNCT
dti-1334	385	3	,	,	PUNCT
dti-1334	385	4	17:994–9	17:994–9	X
dti-1334	385	5	.	.	PUNCT
dti-1334	385	6	hall	hall	PROPN
dti-1334	385	7	,	,	PUNCT
dti-1334	385	8	d.a	d.a	PROPN
dti-1334	385	9	.	.	PROPN
dti-1334	385	10	,	,	PUNCT
dti-1334	385	11	ptacek	ptacek	PROPN
dti-1334	385	12	,	,	PUNCT
dti-1334	385	13	j.	j.	PROPN
dti-1334	385	14	and	and	CCONJ
dti-1334	385	15	snyder	snyder	PROPN
dti-1334	385	16	,	,	PUNCT
dti-1334	385	17	m.	m.	NOUN
dti-1334	385	18	2007	2007	NUM
dti-1334	385	19	.	.	PUNCT
dti-1334	386	1	protein	protein	NOUN
dti-1334	386	2	microarray	microarray	PROPN
dti-1334	386	3	technology	technology	NOUN
dti-1334	386	4	.	.	PUNCT
dti-1334	387	1	mech	mech	NOUN
dti-1334	387	2	.	.	PUNCT
dti-1334	388	1	ageing	age	VERB
dti-1334	388	2	dev	dev	PROPN
dti-1334	388	3	.	.	PROPN
dti-1334	388	4	,	,	PUNCT
dti-1334	389	1	128:161–7	128:161–7	NUM
dti-1334	389	2	.	.	PUNCT
dti-1334	389	3	han	han	PROPN
dti-1334	389	4	,	,	PUNCT
dti-1334	389	5	d.k	d.k	PROPN
dti-1334	389	6	.	.	PROPN
dti-1334	389	7	,	,	PUNCT
dti-1334	389	8	eng	eng	PROPN
dti-1334	389	9	,	,	PUNCT
dti-1334	389	10	j.	j.	PROPN
dti-1334	389	11	,	,	PUNCT
dti-1334	389	12	zhou	zhou	PROPN
dti-1334	389	13	,	,	PUNCT
dti-1334	389	14	h.	h.	PROPN
dti-1334	389	15	and	and	CCONJ
dti-1334	389	16	aebersold	aebersold	PROPN
dti-1334	389	17	,	,	PUNCT
dti-1334	389	18	r.	r.	PROPN
dti-1334	389	19	2001	2001	NUM
dti-1334	389	20	.	.	PUNCT
dti-1334	390	1	quantitative	quantitative	ADJ
dti-1334	390	2	profi	profi	PROPN
dti-1334	390	3	ling	ling	PROPN
dti-1334	390	4	of	of	ADP
dti-1334	390	5	differentiation	differentiation	NOUN
dti-1334	390	6	-	-	PUNCT
dti-1334	390	7	induced	induce	VERB
dti-1334	390	8	microsomal	microsomal	ADJ
dti-1334	390	9	proteins	protein	NOUN
dti-1334	390	10	using	use	VERB
dti-1334	390	11	isotope	isotope	NOUN
dti-1334	390	12	-	-	PUNCT
dti-1334	390	13	coded	code	VERB
dti-1334	390	14	affi	affi	ADJ
dti-1334	390	15	nity	nity	NOUN
dti-1334	390	16	tags	tag	NOUN
dti-1334	390	17	and	and	CCONJ
dti-1334	390	18	mass	mass	ADJ
dti-1334	390	19	spectrometry	spectrometry	NOUN
dti-1334	390	20	.	.	PUNCT
dti-1334	391	1	nat	nat	PROPN
dti-1334	391	2	.	.	PUNCT
dti-1334	392	1	biotechnol	biotechnol	PROPN
dti-1334	392	2	.	.	PROPN
dti-1334	392	3	,	,	PUNCT
dti-1334	392	4	19:946–51	19:946–51	PROPN
dti-1334	392	5	.	.	PUNCT
dti-1334	393	1	hartwell	hartwell	PROPN
dti-1334	393	2	,	,	PUNCT
dti-1334	393	3	l.h	l.h	PROPN
dti-1334	393	4	.	.	PROPN
dti-1334	393	5	,	,	PUNCT
dti-1334	393	6	szankasi	szankasi	PROPN
dti-1334	393	7	,	,	PUNCT
dti-1334	393	8	p.	p.	PROPN
dti-1334	393	9	,	,	PUNCT
dti-1334	393	10	roberts	roberts	PROPN
dti-1334	393	11	,	,	PUNCT
dti-1334	393	12	c.j	c.j	PROPN
dti-1334	393	13	.	.	PROPN
dti-1334	393	14	,	,	PUNCT
dti-1334	393	15	murray	murray	PROPN
dti-1334	393	16	,	,	PUNCT
dti-1334	393	17	a.w	a.w	PROPN
dti-1334	393	18	.	.	PROPN
dti-1334	393	19	and	and	CCONJ
dti-1334	393	20	friend	friend	NOUN
dti-1334	393	21	,	,	PUNCT
dti-1334	393	22	s.h	s.h	PROPN
dti-1334	393	23	.	.	PROPN
dti-1334	393	24	1997	1997	NUM
dti-1334	393	25	.	.	PUNCT
dti-1334	394	1	integrating	integrate	VERB
dti-1334	394	2	genetic	genetic	ADJ
dti-1334	394	3	approaches	approach	NOUN
dti-1334	394	4	into	into	ADP
dti-1334	394	5	the	the	DET
dti-1334	394	6	discovery	discovery	NOUN
dti-1334	394	7	of	of	ADP
dti-1334	394	8	anticancer	anticancer	NOUN
dti-1334	394	9	drugs	drug	NOUN
dti-1334	394	10	.	.	PUNCT
dti-1334	395	1	science	science	NOUN
dti-1334	395	2	,	,	PUNCT
dti-1334	395	3	278:1064–8	278:1064–8	NUM
dti-1334	395	4	.	.	PUNCT
dti-1334	396	1	henkel	henkel	PROPN
dti-1334	396	2	,	,	PUNCT
dti-1334	396	3	c.	c.	PROPN
dti-1334	396	4	,	,	PUNCT
dti-1334	396	5	roderfeld	roderfeld	NOUN
dti-1334	396	6	,	,	PUNCT
dti-1334	396	7	m.	m.	NOUN
dti-1334	396	8	,	,	PUNCT
dti-1334	396	9	weiskirchen	weiskirchen	PROPN
dti-1334	396	10	,	,	PUNCT
dti-1334	396	11	r.	r.	PROPN
dti-1334	396	12	,	,	PUNCT
dti-1334	396	13	berres	berre	NOUN
dti-1334	396	14	,	,	PUNCT
dti-1334	396	15	m.l	m.l	PROPN
dti-1334	396	16	.	.	PROPN
dti-1334	396	17	,	,	PUNCT
dti-1334	396	18	hillebrandt	hillebrandt	PROPN
dti-1334	396	19	,	,	PUNCT
dti-1334	396	20	s.	s.	PROPN
dti-1334	396	21	,	,	PUNCT
dti-1334	396	22	lammert	lammert	PROPN
dti-1334	396	23	,	,	PUNCT
dti-1334	396	24	f.	f.	PROPN
dti-1334	396	25	,	,	PUNCT
dti-1334	396	26	meyer	meyer	PROPN
dti-1334	396	27	,	,	PUNCT
dti-1334	396	28	h.e	h.e	PROPN
dti-1334	396	29	.	.	PROPN
dti-1334	396	30	,	,	PUNCT
dti-1334	396	31	stuhler	stuhler	PROPN
dti-1334	396	32	,	,	PUNCT
dti-1334	396	33	k.	k.	PROPN
dti-1334	396	34	,	,	PUNCT
dti-1334	396	35	graf	graf	PROPN
dti-1334	396	36	,	,	PUNCT
dti-1334	396	37	j.	j.	PROPN
dti-1334	396	38	and	and	CCONJ
dti-1334	396	39	roeb	roeb	PROPN
dti-1334	396	40	,	,	PUNCT
dti-1334	396	41	e.	e.	PROPN
dti-1334	396	42	2006	2006	NUM
dti-1334	396	43	.	.	PUNCT
dti-1334	397	1	changes	change	NOUN
dti-1334	397	2	of	of	ADP
dti-1334	397	3	the	the	DET
dti-1334	397	4	hepatic	hepatic	ADJ
dti-1334	397	5	proteome	proteome	NOUN
dti-1334	397	6	in	in	ADP
dti-1334	397	7	murine	murine	ADJ
dti-1334	397	8	models	model	NOUN
dti-1334	397	9	for	for	ADP
dti-1334	397	10	toxically	toxically	ADV
dti-1334	397	11	induced	induce	VERB
dti-1334	397	12	fi	fi	NOUN
dti-1334	397	13	brogenesis	brogenesis	NOUN
dti-1334	397	14	and	and	CCONJ
dti-1334	397	15	sclerosing	sclerose	VERB
dti-1334	397	16	cholangitis	cholangitis	NOUN
dti-1334	397	17	.	.	PUNCT
dti-1334	398	1	proteomics	proteomic	NOUN
dti-1334	398	2	,	,	PUNCT
dti-1334	398	3	6:6538–48	6:6538–48	NOUN
dti-1334	398	4	.	.	PUNCT
dti-1334	399	1	hu	hu	PROPN
dti-1334	399	2	,	,	PUNCT
dti-1334	399	3	y.	y.	PROPN
dti-1334	399	4	,	,	PUNCT
dti-1334	399	5	wang	wang	PROPN
dti-1334	399	6	,	,	PUNCT
dti-1334	399	7	g.	g.	PROPN
dti-1334	399	8	,	,	PUNCT
dti-1334	399	9	chen	chen	PROPN
dti-1334	399	10	,	,	PUNCT
dti-1334	399	11	g.y	g.y	PROPN
dti-1334	399	12	.	.	PROPN
dti-1334	399	13	,	,	PUNCT
dti-1334	399	14	fu	fu	PROPN
dti-1334	399	15	,	,	PUNCT
dti-1334	399	16	x.	x.	NOUN
dti-1334	399	17	and	and	CCONJ
dti-1334	399	18	yao	yao	PROPN
dti-1334	399	19	,	,	PUNCT
dti-1334	399	20	s.q	s.q	PROPN
dti-1334	399	21	.	.	PROPN
dti-1334	399	22	2003	2003	NUM
dti-1334	399	23	.	.	PUNCT
dti-1334	400	1	proteome	proteome	ADJ
dti-1334	400	2	analysis	analysis	NOUN
dti-1334	400	3	of	of	ADP
dti-1334	400	4	saccharomyces	saccharomyce	NOUN
dti-1334	400	5	cerevisiae	cerevisiae	NOUN
dti-1334	400	6	under	under	ADP
dti-1334	400	7	metal	metal	NOUN
dti-1334	400	8	stress	stress	NOUN
dti-1334	400	9	by	by	ADP
dti-1334	400	10	two	two	NUM
dti-1334	400	11	-	-	PUNCT
dti-1334	400	12	dimensional	dimensional	ADJ
dti-1334	400	13	differential	differential	ADJ
dti-1334	400	14	gel	gel	NOUN
dti-1334	400	15	electrophoresis	electrophoresis	NOUN
dti-1334	400	16	.	.	PUNCT
dti-1334	401	1	electrophoresis	electrophoresis	NOUN
dti-1334	401	2	,	,	PUNCT
dti-1334	401	3	24:1458–70	24:1458–70	NUM
dti-1334	401	4	.	.	PUNCT
dti-1334	402	1	jensen	jensen	PROPN
dti-1334	402	2	,	,	PUNCT
dti-1334	402	3	o.n	o.n	PROPN
dti-1334	402	4	.	.	PROPN
dti-1334	402	5	2006	2006	NUM
dti-1334	402	6	.	.	PUNCT
dti-1334	403	1	interpreting	interpret	VERB
dti-1334	403	2	the	the	DET
dti-1334	403	3	protein	protein	NOUN
dti-1334	403	4	language	language	NOUN
dti-1334	403	5	using	use	VERB
dti-1334	403	6	proteomics	proteomic	NOUN
dti-1334	403	7	.	.	PUNCT
dti-1334	404	1	nat	nat	PROPN
dti-1334	404	2	.	.	PUNCT
dti-1334	405	1	rev	rev	PROPN
dti-1334	405	2	.	.	PROPN
dti-1334	405	3	mol	mol	PROPN
dti-1334	405	4	.	.	PROPN
dti-1334	406	1	cell	cell	NOUN
dti-1334	406	2	.	.	PUNCT
dti-1334	407	1	biol	biol	PROPN
dti-1334	407	2	.	.	PUNCT
dti-1334	407	3	,	,	PUNCT
dti-1334	408	1	7:391–403	7:391–403	PROPN
dti-1334	408	2	.	.	PUNCT
dti-1334	409	1	jeong	jeong	PROPN
dti-1334	409	2	,	,	PUNCT
dti-1334	409	3	h.	h.	PROPN
dti-1334	409	4	,	,	PUNCT
dti-1334	409	5	mason	mason	PROPN
dti-1334	409	6	,	,	PUNCT
dti-1334	409	7	s.p	s.p	PROPN
dti-1334	409	8	.	.	PROPN
dti-1334	409	9	,	,	PUNCT
dti-1334	409	10	barabasi	barabasi	PROPN
dti-1334	409	11	,	,	PUNCT
dti-1334	409	12	a.l	a.l	PROPN
dti-1334	409	13	.	.	PROPN
dti-1334	410	1	and	and	CCONJ
dti-1334	410	2	oltvai	oltvai	ADV
dti-1334	410	3	,	,	PUNCT
dti-1334	410	4	z.n	z.n	PROPN
dti-1334	410	5	.	.	PROPN
dti-1334	410	6	2001	2001	NUM
dti-1334	410	7	.	.	PUNCT
dti-1334	411	1	lethality	lethality	NOUN
dti-1334	411	2	and	and	CCONJ
dti-1334	411	3	centrality	centrality	NOUN
dti-1334	411	4	in	in	ADP
dti-1334	411	5	protein	protein	NOUN
dti-1334	411	6	networks	network	NOUN
dti-1334	411	7	.	.	PUNCT
dti-1334	412	1	nature	nature	NOUN
dti-1334	412	2	,	,	PUNCT
dti-1334	412	3	411:41–2	411:41–2	NUM
dti-1334	412	4	.	.	PUNCT
dti-1334	413	1	jin	jin	NOUN
dti-1334	413	2	,	,	PUNCT
dti-1334	413	3	t.	t.	PROPN
dti-1334	413	4	,	,	PUNCT
dti-1334	413	5	hu	hu	PROPN
dti-1334	413	6	,	,	PUNCT
dti-1334	413	7	l.s	l.s	PROPN
dti-1334	413	8	.	.	PROPN
dti-1334	413	9	,	,	PUNCT
dti-1334	413	10	chang	chang	PROPN
dti-1334	413	11	,	,	PUNCT
dti-1334	413	12	m.	m.	NOUN
dti-1334	413	13	,	,	PUNCT
dti-1334	413	14	wu	wu	PROPN
dti-1334	413	15	,	,	PUNCT
dti-1334	413	16	j.	j.	PROPN
dti-1334	413	17	,	,	PUNCT
dti-1334	413	18	winblad	winblad	PROPN
dti-1334	413	19	,	,	PUNCT
dti-1334	413	20	b.	b.	PROPN
dti-1334	413	21	and	and	CCONJ
dti-1334	413	22	zhu	zhu	PROPN
dti-1334	413	23	,	,	PUNCT
dti-1334	413	24	j.	j.	PROPN
dti-1334	413	25	2007	2007	NUM
dti-1334	413	26	.	.	PUNCT
dti-1334	414	1	proteomic	proteomic	ADJ
dti-1334	414	2	identifi	identifi	PROPN
dti-1334	414	3	cation	cation	NOUN
dti-1334	414	4	of	of	ADP
dti-1334	414	5	potential	potential	ADJ
dti-1334	414	6	protein	protein	NOUN
dti-1334	414	7	markers	marker	NOUN
dti-1334	414	8	in	in	ADP
dti-1334	414	9	cerebrospinal	cerebrospinal	ADJ
dti-1334	414	10	fl	fl	NOUN
dti-1334	414	11	uid	uid	PROPN
dti-1334	414	12	of	of	ADP
dti-1334	414	13	gbs	gbs	PROPN
dti-1334	414	14	patients	patient	NOUN
dti-1334	414	15	.	.	PUNCT
dti-1334	415	1	eur	eur	PROPN
dti-1334	415	2	.	.	PUNCT
dti-1334	416	1	j.	j.	PROPN
dti-1334	416	2	neurol	neurol	PROPN
dti-1334	416	3	.	.	PUNCT
dti-1334	416	4	,	,	PUNCT
dti-1334	416	5	14:563–8	14:563–8	NUM
dti-1334	416	6	.	.	PUNCT
dti-1334	417	1	karp	karp	PROPN
dti-1334	417	2	,	,	PUNCT
dti-1334	417	3	p.d	p.d	PROPN
dti-1334	417	4	.	.	PROPN
dti-1334	417	5	1998	1998	NUM
dti-1334	417	6	.	.	PUNCT
dti-1334	418	1	metabolic	metabolic	NOUN
dti-1334	418	2	databases	database	NOUN
dti-1334	418	3	.	.	PUNCT
dti-1334	419	1	trends	trend	NOUN
dti-1334	419	2	biochem	biochem	PROPN
dti-1334	419	3	.	.	PUNCT
dti-1334	420	1	sci	sci	PROPN
dti-1334	420	2	.	.	PROPN
dti-1334	420	3	,	,	PUNCT
dti-1334	420	4	23:114–6	23:114–6	NUM
dti-1334	420	5	.	.	PUNCT
dti-1334	421	1	karp	karp	PROPN
dti-1334	421	2	,	,	PUNCT
dti-1334	421	3	p.d	p.d	PROPN
dti-1334	421	4	.	.	PROPN
dti-1334	421	5	2001	2001	NUM
dti-1334	421	6	.	.	PUNCT
dti-1334	422	1	pathway	pathway	NOUN
dti-1334	422	2	databases	database	NOUN
dti-1334	422	3	:	:	PUNCT
dti-1334	422	4	a	a	DET
dti-1334	422	5	case	case	NOUN
dti-1334	422	6	study	study	NOUN
dti-1334	422	7	in	in	ADP
dti-1334	422	8	computational	computational	ADJ
dti-1334	422	9	symbolic	symbolic	ADJ
dti-1334	422	10	theories	theory	NOUN
dti-1334	422	11	.	.	PUNCT
dti-1334	423	1	science	science	NOUN
dti-1334	423	2	,	,	PUNCT
dti-1334	423	3	293:2040–4	293:2040–4	NUM
dti-1334	423	4	.	.	PUNCT
dti-1334	424	1	keeler	keeler	PROPN
dti-1334	424	2	,	,	PUNCT
dti-1334	424	3	m.	m.	NOUN
dti-1334	424	4	,	,	PUNCT
dti-1334	424	5	letarte	letarte	PROPN
dti-1334	424	6	,	,	PUNCT
dti-1334	424	7	j.	j.	PROPN
dti-1334	424	8	,	,	PUNCT
dti-1334	424	9	hattrup	hattrup	PROPN
dti-1334	424	10	,	,	PUNCT
dti-1334	424	11	e.	e.	PROPN
dti-1334	424	12	,	,	PUNCT
dti-1334	424	13	hickman	hickman	PROPN
dti-1334	424	14	,	,	PUNCT
dti-1334	424	15	f.	f.	PROPN
dti-1334	424	16	and	and	CCONJ
dti-1334	424	17	haynes	haynes	PROPN
dti-1334	424	18	,	,	PUNCT
dti-1334	424	19	p.a	p.a	PROPN
dti-1334	424	20	.	.	PROPN
dti-1334	424	21	2007	2007	NUM
dti-1334	424	22	.	.	PUNCT
dti-1334	425	1	twodimensional	twodimensional	ADJ
dti-1334	425	2	differential	differential	NOUN
dti-1334	425	3	in	in	ADP
dti-1334	425	4	-	-	PUNCT
dti-1334	425	5	gel	gel	NOUN
dti-1334	425	6	electrophoresis	electrophoresis	NOUN
dti-1334	425	7	(	(	PUNCT
dti-1334	425	8	dige	dige	NOUN
dti-1334	425	9	)	)	PUNCT
dti-1334	425	10	of	of	ADP
dti-1334	425	11	leaf	leaf	NOUN
dti-1334	425	12	and	and	CCONJ
dti-1334	425	13	roots	root	NOUN
dti-1334	425	14	of	of	ADP
dti-1334	425	15	lycopersicon	lycopersicon	PROPN
dti-1334	425	16	esculentum	esculentum	PROPN
dti-1334	425	17	.	.	PUNCT
dti-1334	426	1	methods	methods	PROPN
dti-1334	426	2	mol	mol	PROPN
dti-1334	426	3	.	.	PUNCT
dti-1334	427	1	biol	biol	PROPN
dti-1334	427	2	.	.	PUNCT
dti-1334	427	3	,	,	PUNCT
dti-1334	428	1	355:157–74	355:157–74	NUM
dti-1334	428	2	.	.	PUNCT
dti-1334	429	1	kisby	kisby	PROPN
dti-1334	429	2	,	,	PUNCT
dti-1334	429	3	g.e	g.e	PROPN
dti-1334	429	4	.	.	PROPN
dti-1334	429	5	,	,	PUNCT
dti-1334	429	6	standley	standley	PROPN
dti-1334	429	7	,	,	PUNCT
dti-1334	429	8	m.	m.	NOUN
dti-1334	429	9	,	,	PUNCT
dti-1334	429	10	park	park	NOUN
dti-1334	429	11	,	,	PUNCT
dti-1334	429	12	t.	t.	PROPN
dti-1334	429	13	,	,	PUNCT
dti-1334	429	14	olivas	olivas	PROPN
dti-1334	429	15	,	,	PUNCT
dti-1334	429	16	a.	a.	PROPN
dti-1334	429	17	,	,	PUNCT
dti-1334	429	18	fei	fei	PROPN
dti-1334	429	19	,	,	PUNCT
dti-1334	429	20	s.	s.	PROPN
dti-1334	429	21	,	,	PUNCT
dti-1334	429	22	jacob	jacob	PROPN
dti-1334	429	23	,	,	PUNCT
dti-1334	429	24	t.	t.	PROPN
dti-1334	429	25	,	,	PUNCT
dti-1334	429	26	reddy	reddy	PROPN
dti-1334	429	27	,	,	PUNCT
dti-1334	429	28	a.	a.	PROPN
dti-1334	429	29	,	,	PUNCT
dti-1334	429	30	lu	lu	PROPN
dti-1334	429	31	,	,	PUNCT
dti-1334	429	32	x.	x.	NOUN
dti-1334	429	33	,	,	PUNCT
dti-1334	429	34	pattee	pattee	NOUN
dti-1334	429	35	,	,	PUNCT
dti-1334	429	36	p.	p.	NOUN
dti-1334	429	37	and	and	CCONJ
dti-1334	429	38	nagalla	nagalla	PROPN
dti-1334	429	39	,	,	PUNCT
dti-1334	429	40	s.r	s.r	PROPN
dti-1334	429	41	.	.	PROPN
dti-1334	429	42	2006	2006	NUM
dti-1334	429	43	.	.	PUNCT
dti-1334	430	1	proteomic	proteomic	ADJ
dti-1334	430	2	analysis	analysis	NOUN
dti-1334	430	3	of	of	ADP
dti-1334	430	4	the	the	DET
dti-1334	430	5	genotoxicant	genotoxicant	ADJ
dti-1334	430	6	methylazoxymethanol	methylazoxymethanol	NOUN
dti-1334	430	7	(	(	PUNCT
dti-1334	430	8	mam)-induced	mam)-induce	VERB
dti-1334	430	9	changes	change	NOUN
dti-1334	430	10	in	in	ADP
dti-1334	430	11	the	the	DET
dti-1334	430	12	developing	develop	VERB
dti-1334	430	13	cerebellum	cerebellum	NOUN
dti-1334	430	14	.	.	PUNCT
dti-1334	431	1	j.	j.	PROPN
dti-1334	431	2	proteome	proteome	PROPN
dti-1334	431	3	res	res	PROPN
dti-1334	431	4	.	.	PROPN
dti-1334	431	5	,	,	PUNCT
dti-1334	431	6	5:2656–65	5:2656–65	NUM
dti-1334	431	7	.	.	PUNCT
dti-1334	432	1	kislinger	kislinger	NOUN
dti-1334	432	2	,	,	PUNCT
dti-1334	432	3	t.	t.	PROPN
dti-1334	432	4	,	,	PUNCT
dti-1334	432	5	gramolini	gramolini	NOUN
dti-1334	432	6	,	,	PUNCT
dti-1334	432	7	a.o	a.o	PROPN
dti-1334	432	8	.	.	PROPN
dti-1334	432	9	,	,	PUNCT
dti-1334	432	10	maclennan	maclennan	PROPN
dti-1334	432	11	,	,	PUNCT
dti-1334	432	12	d.h	d.h	PROPN
dti-1334	432	13	.	.	PROPN
dti-1334	432	14	and	and	CCONJ
dti-1334	432	15	emili	emili	NOUN
dti-1334	432	16	,	,	PUNCT
dti-1334	432	17	a.	a.	NOUN
dti-1334	432	18	2005	2005	NUM
dti-1334	432	19	.	.	PUNCT
dti-1334	433	1	multidimensional	multidimensional	ADJ
dti-1334	433	2	protein	protein	NOUN
dti-1334	433	3	identifi	identifi	PROPN
dti-1334	433	4	cation	cation	NOUN
dti-1334	433	5	technology	technology	NOUN
dti-1334	433	6	(	(	PUNCT
dti-1334	433	7	mudpit	mudpit	NOUN
dti-1334	433	8	):	):	PUNCT
dti-1334	433	9	technical	technical	ADJ
dti-1334	433	10	overview	overview	NOUN
dti-1334	433	11	of	of	ADP
dti-1334	433	12	a	a	DET
dti-1334	433	13	profi	profi	ADJ
dti-1334	433	14	ling	ling	PROPN
dti-1334	433	15	method	method	NOUN
dti-1334	433	16	optimized	optimize	VERB
dti-1334	433	17	for	for	ADP
dti-1334	433	18	the	the	DET
dti-1334	433	19	comprehensive	comprehensive	ADJ
dti-1334	433	20	proteomic	proteomic	ADJ
dti-1334	433	21	investigation	investigation	NOUN
dti-1334	433	22	of	of	ADP
dti-1334	433	23	normal	normal	ADJ
dti-1334	433	24	and	and	CCONJ
dti-1334	433	25	diseased	diseased	ADJ
dti-1334	433	26	heart	heart	NOUN
dti-1334	433	27	tissue	tissue	NOUN
dti-1334	433	28	.	.	PUNCT
dti-1334	434	1	j.	j.	PROPN
dti-1334	434	2	am	am	PROPN
dti-1334	434	3	.	.	PUNCT
dti-1334	435	1	soc	soc	PROPN
dti-1334	435	2	.	.	PUNCT
dti-1334	436	1	mass	mass	PROPN
dti-1334	436	2	spectrom	spectrom	PROPN
dti-1334	436	3	,	,	PUNCT
dti-1334	436	4	16:1207–20	16:1207–20	NUM
dti-1334	436	5	.	.	PUNCT
dti-1334	437	1	kondo	kondo	PROPN
dti-1334	437	2	,	,	PUNCT
dti-1334	437	3	t.	t.	PROPN
dti-1334	437	4	and	and	CCONJ
dti-1334	437	5	hirohashi	hirohashi	PROPN
dti-1334	437	6	,	,	PUNCT
dti-1334	437	7	s.	s.	PROPN
dti-1334	437	8	2006	2006	NUM
dti-1334	437	9	.	.	PUNCT
dti-1334	438	1	application	application	NOUN
dti-1334	438	2	of	of	ADP
dti-1334	438	3	highly	highly	ADV
dti-1334	438	4	sensitive	sensitive	ADJ
dti-1334	438	5	fl	fl	PRON
dti-1334	438	6	uorescent	uorescent	ADJ
dti-1334	438	7	dyes	dye	NOUN
dti-1334	438	8	(	(	PUNCT
dti-1334	438	9	cydye	cydye	NOUN
dti-1334	438	10	dige	dige	NOUN
dti-1334	438	11	fluor	fluor	NOUN
dti-1334	438	12	saturation	saturation	NOUN
dti-1334	438	13	dyes	dye	NOUN
dti-1334	438	14	)	)	PUNCT
dti-1334	438	15	to	to	PART
dti-1334	438	16	laser	laser	VERB
dti-1334	438	17	microdissection	microdissection	NOUN
dti-1334	438	18	and	and	CCONJ
dti-1334	438	19	two	two	NUM
dti-1334	438	20	-	-	PUNCT
dti-1334	438	21	dimensional	dimensional	ADJ
dti-1334	438	22	difference	difference	NOUN
dti-1334	438	23	gel	gel	NOUN
dti-1334	438	24	electrophoresis	electrophoresis	NOUN
dti-1334	438	25	(	(	PUNCT
dti-1334	438	26	2d	2d	NOUN
dti-1334	438	27	-	-	PUNCT
dti-1334	438	28	dige	dige	NOUN
dti-1334	438	29	)	)	PUNCT
dti-1334	438	30	for	for	ADP
dti-1334	438	31	cancer	cancer	NOUN
dti-1334	438	32	proteomics	proteomic	NOUN
dti-1334	438	33	.	.	PUNCT
dti-1334	439	1	nat	nat	PROPN
dti-1334	439	2	.	.	PUNCT
dti-1334	440	1	protoc	protoc	VERB
dti-1334	440	2	.	.	PUNCT
dti-1334	441	1	,	,	PUNCT
dti-1334	441	2	1:2940–56	1:2940–56	NUM
dti-1334	441	3	.	.	PUNCT
dti-1334	442	1	kopf	kopf	PROPN
dti-1334	442	2	,	,	PUNCT
dti-1334	442	3	e.	e.	PROPN
dti-1334	442	4	and	and	CCONJ
dti-1334	442	5	zharhary	zharhary	PROPN
dti-1334	442	6	,	,	PUNCT
dti-1334	442	7	d.	d.	PROPN
dti-1334	442	8	2007	2007	NUM
dti-1334	442	9	.	.	PUNCT
dti-1334	443	1	antibody	antibody	NOUN
dti-1334	443	2	arrays	array	VERB
dti-1334	443	3	-	-	PUNCT
dti-1334	443	4	an	an	DET
dti-1334	443	5	emerging	emerge	VERB
dti-1334	443	6	tool	tool	NOUN
dti-1334	443	7	in	in	ADP
dti-1334	443	8	cancer	cancer	NOUN
dti-1334	443	9	proteomics	proteomic	NOUN
dti-1334	443	10	.	.	PUNCT
dti-1334	444	1	int	int	NOUN
dti-1334	444	2	.	.	PUNCT
dti-1334	445	1	j.	j.	PROPN
dti-1334	445	2	biochem	biochem	PROPN
dti-1334	445	3	.	.	PUNCT
dti-1334	446	1	cell	cell	NOUN
dti-1334	446	2	.	.	PUNCT
dti-1334	447	1	biol	biol	PROPN
dti-1334	447	2	.	.	PUNCT
dti-1334	447	3	,	,	PUNCT
dti-1334	447	4	39:1305–17	39:1305–17	NUM
dti-1334	447	5	.	.	PUNCT
dti-1334	448	1	lage	lage	PROPN
dti-1334	448	2	,	,	PUNCT
dti-1334	448	3	h.	h.	PROPN
dti-1334	448	4	2005	2005	NUM
dti-1334	448	5	.	.	PUNCT
dti-1334	449	1	potential	potential	ADJ
dti-1334	449	2	applications	application	NOUN
dti-1334	449	3	of	of	ADP
dti-1334	449	4	rna	rna	NOUN
dti-1334	449	5	interference	interference	NOUN
dti-1334	449	6	technology	technology	NOUN
dti-1334	449	7	in	in	ADP
dti-1334	449	8	the	the	DET
dti-1334	449	9	treatment	treatment	NOUN
dti-1334	449	10	of	of	ADP
dti-1334	449	11	cancer	cancer	NOUN
dti-1334	449	12	.	.	PUNCT
dti-1334	450	1	future	future	ADJ
dti-1334	450	2	oncol	oncol	PROPN
dti-1334	450	3	.	.	PUNCT
dti-1334	450	4	,	,	PUNCT
dti-1334	451	1	1:103–13	1:103–13	PROPN
dti-1334	451	2	.	.	PUNCT
dti-1334	452	1	liang	liang	PROPN
dti-1334	452	2	,	,	PUNCT
dti-1334	452	3	x.	x.	PROPN
dti-1334	452	4	,	,	PUNCT
dti-1334	452	5	hajivandi	hajivandi	NOUN
dti-1334	452	6	,	,	PUNCT
dti-1334	452	7	m.	m.	NOUN
dti-1334	452	8	,	,	PUNCT
dti-1334	452	9	veach	veach	NOUN
dti-1334	452	10	,	,	PUNCT
dti-1334	452	11	d.	d.	PROPN
dti-1334	452	12	,	,	PUNCT
dti-1334	452	13	wisniewski	wisniewski	PROPN
dti-1334	452	14	,	,	PUNCT
dti-1334	452	15	d.	d.	PROPN
dti-1334	452	16	,	,	PUNCT
dti-1334	452	17	clarkson	clarkson	PROPN
dti-1334	452	18	,	,	PUNCT
dti-1334	452	19	b.	b.	PROPN
dti-1334	452	20	,	,	PUNCT
dti-1334	452	21	resh	resh	PROPN
dti-1334	452	22	,	,	PUNCT
dti-1334	452	23	m.d	m.d	PROPN
dti-1334	452	24	.	.	PROPN
dti-1334	452	25	and	and	CCONJ
dti-1334	452	26	pope	pope	PROPN
dti-1334	452	27	,	,	PUNCT
dti-1334	452	28	r.m	r.m	PROPN
dti-1334	452	29	.	.	PROPN
dti-1334	452	30	2006	2006	NUM
dti-1334	452	31	.	.	PUNCT
dti-1334	453	1	quantifi	quantifi	ADJ
dti-1334	453	2	cation	cation	NOUN
dti-1334	453	3	of	of	ADP
dti-1334	453	4	change	change	NOUN
dti-1334	453	5	in	in	ADP
dti-1334	453	6	phosphorylation	phosphorylation	NOUN
dti-1334	453	7	of	of	ADP
dti-1334	453	8	bcr	bcr	PROPN
dti-1334	453	9	-	-	PROPN
dti-1334	453	10	abl	abl	PROPN
dti-1334	453	11	kinase	kinase	NOUN
dti-1334	453	12	and	and	CCONJ
dti-1334	453	13	its	its	PRON
dti-1334	453	14	substrates	substrate	NOUN
dti-1334	453	15	in	in	ADP
dti-1334	453	16	response	response	NOUN
dti-1334	453	17	to	to	ADP
dti-1334	453	18	imatinib	imatinib	NOUN
dti-1334	453	19	treatment	treatment	NOUN
dti-1334	453	20	in	in	ADP
dti-1334	453	21	human	human	ADJ
dti-1334	453	22	chronic	chronic	ADJ
dti-1334	453	23	myelogenous	myelogenous	ADJ
dti-1334	453	24	leukemia	leukemia	NOUN
dti-1334	453	25	cells	cell	NOUN
dti-1334	453	26	.	.	PUNCT
dti-1334	454	1	proteomics	proteomic	NOUN
dti-1334	454	2	,	,	PUNCT
dti-1334	454	3	6:4554–64	6:4554–64	PROPN
dti-1334	454	4	.	.	PUNCT
dti-1334	455	1	lilley	lilley	PROPN
dti-1334	455	2	,	,	PUNCT
dti-1334	455	3	k.s	k.s	PROPN
dti-1334	455	4	.	.	PROPN
dti-1334	455	5	and	and	CCONJ
dti-1334	455	6	friedman	friedman	PROPN
dti-1334	455	7	,	,	PUNCT
dti-1334	455	8	d.b	d.b	PROPN
dti-1334	455	9	.	.	PROPN
dti-1334	455	10	2004	2004	NUM
dti-1334	455	11	.	.	PUNCT
dti-1334	456	1	all	all	PRON
dti-1334	456	2	about	about	ADP
dti-1334	456	3	dige	dige	NOUN
dti-1334	456	4	:	:	PUNCT
dti-1334	456	5	quantifi	quantifi	ADJ
dti-1334	456	6	cation	cation	NOUN
dti-1334	456	7	technology	technology	NOUN
dti-1334	456	8	for	for	ADP
dti-1334	456	9	differential	differential	ADJ
dti-1334	456	10	-	-	PUNCT
dti-1334	456	11	display	display	NOUN
dti-1334	456	12	2d	2d	NOUN
dti-1334	456	13	-	-	PUNCT
dti-1334	456	14	gel	gel	NOUN
dti-1334	456	15	proteomics	proteomic	NOUN
dti-1334	456	16	.	.	PUNCT
dti-1334	457	1	expert	expert	PROPN
dti-1334	457	2	rev	rev	PROPN
dti-1334	457	3	.	.	PROPN
dti-1334	457	4	proteomics	proteomic	NOUN
dti-1334	457	5	,	,	PUNCT
dti-1334	457	6	1:401–9	1:401–9	NUM
dti-1334	457	7	.	.	PUNCT
dti-1334	458	1	lueking	lueking	NOUN
dti-1334	458	2	,	,	PUNCT
dti-1334	458	3	a.	a.	PROPN
dti-1334	458	4	,	,	PUNCT
dti-1334	458	5	cahill	cahill	PROPN
dti-1334	458	6	,	,	PUNCT
dti-1334	458	7	d.j	d.j	PROPN
dti-1334	458	8	.	.	PROPN
dti-1334	458	9	and	and	CCONJ
dti-1334	458	10	mullner	mullner	PROPN
dti-1334	458	11	,	,	PUNCT
dti-1334	458	12	s.	s.	PROPN
dti-1334	458	13	2005	2005	NUM
dti-1334	458	14	.	.	PUNCT
dti-1334	459	1	protein	protein	NOUN
dti-1334	459	2	biochips	biochip	NOUN
dti-1334	459	3	:	:	PUNCT
dti-1334	459	4	a	a	DET
dti-1334	459	5	new	new	ADJ
dti-1334	459	6	and	and	CCONJ
dti-1334	459	7	versatile	versatile	ADJ
dti-1334	459	8	platform	platform	NOUN
dti-1334	459	9	technology	technology	NOUN
dti-1334	459	10	for	for	ADP
dti-1334	459	11	molecular	molecular	ADJ
dti-1334	459	12	medicine	medicine	NOUN
dti-1334	459	13	.	.	PUNCT
dti-1334	460	1	drug	drug	NOUN
dti-1334	460	2	discov	discov	NOUN
dti-1334	460	3	.	.	PUNCT
dti-1334	461	1	today	today	NOUN
dti-1334	461	2	,	,	PUNCT
dti-1334	461	3	10:789–94	10:789–94	NUM
dti-1334	461	4	.	.	PUNCT
dti-1334	462	1	lyakhovich	lyakhovich	ADJ
dti-1334	462	2	,	,	PUNCT
dti-1334	462	3	a.	a.	NOUN
dti-1334	462	4	,	,	PUNCT
dti-1334	462	5	canals	canal	NOUN
dti-1334	462	6	,	,	PUNCT
dti-1334	462	7	f.	f.	PROPN
dti-1334	462	8	,	,	PUNCT
dti-1334	462	9	nosov	nosov	NOUN
dti-1334	462	10	,	,	PUNCT
dti-1334	462	11	m.	m.	NOUN
dti-1334	462	12	and	and	CCONJ
dti-1334	462	13	surralles	surralle	NOUN
dti-1334	462	14	,	,	PUNCT
dti-1334	462	15	j.	j.	PROPN
dti-1334	462	16	2007	2007	NUM
dti-1334	462	17	.	.	PUNCT
dti-1334	463	1	a	a	DET
dti-1334	463	2	dige	dige	NOUN
dti-1334	463	3	-	-	PUNCT
dti-1334	463	4	based	base	VERB
dti-1334	463	5	approach	approach	NOUN
dti-1334	463	6	to	to	PART
dti-1334	463	7	study	study	VERB
dti-1334	463	8	interacting	interacting	ADJ
dti-1334	463	9	proteins	protein	NOUN
dti-1334	463	10	.	.	PUNCT
dti-1334	464	1	j.	j.	PROPN
dti-1334	464	2	biochem	biochem	PROPN
dti-1334	464	3	.	.	PUNCT
dti-1334	465	1	biophys	biophy	NOUN
dti-1334	465	2	.	.	PUNCT
dti-1334	466	1	methods	method	NOUN
dti-1334	466	2	,	,	PUNCT
dti-1334	466	3	70:693–5	70:693–5	NUM
dti-1334	466	4	.	.	PUNCT
dti-1334	466	5	maitra	maitra	PROPN
dti-1334	466	6	,	,	PUNCT
dti-1334	466	7	a.	a.	NOUN
dti-1334	466	8	,	,	PUNCT
dti-1334	466	9	wistuba	wistuba	PROPN
dti-1334	466	10	,	,	PUNCT
dti-1334	466	11	i.i	i.i	PROPN
dti-1334	466	12	.	.	PROPN
dti-1334	466	13	and	and	CCONJ
dti-1334	466	14	gazdar	gazdar	PROPN
dti-1334	466	15	,	,	PUNCT
dti-1334	466	16	a.f	a.f	PROPN
dti-1334	466	17	.	.	PROPN
dti-1334	466	18	2001	2001	NUM
dti-1334	466	19	.	.	PUNCT
dti-1334	467	1	microdissection	microdissection	NOUN
dti-1334	467	2	and	and	CCONJ
dti-1334	467	3	the	the	DET
dti-1334	467	4	study	study	NOUN
dti-1334	467	5	of	of	ADP
dti-1334	467	6	cancer	cancer	NOUN
dti-1334	467	7	pathways	pathway	NOUN
dti-1334	467	8	.	.	PUNCT
dti-1334	468	1	curr	curr	AUX
dti-1334	468	2	.	.	PUNCT
dti-1334	468	3	mol	mol	PROPN
dti-1334	468	4	.	.	PROPN
dti-1334	468	5	med	med	PROPN
dti-1334	468	6	.	.	PROPN
dti-1334	468	7	,	,	PUNCT
dti-1334	469	1	1:153–62	1:153–62	NUM
dti-1334	469	2	.	.	PUNCT
dti-1334	469	3	maurya	maurya	PROPN
dti-1334	469	4	,	,	PUNCT
dti-1334	469	5	p.	p.	NOUN
dti-1334	469	6	,	,	PUNCT
dti-1334	469	7	meleady	meleady	NOUN
dti-1334	469	8	,	,	PUNCT
dti-1334	469	9	p.	p.	NOUN
dti-1334	469	10	,	,	PUNCT
dti-1334	469	11	dowling	dowle	VERB
dti-1334	469	12	,	,	PUNCT
dti-1334	469	13	p.	p.	NOUN
dti-1334	469	14	and	and	CCONJ
dti-1334	469	15	clynes	clyne	NOUN
dti-1334	469	16	,	,	PUNCT
dti-1334	469	17	m.	m.	NOUN
dti-1334	469	18	2007	2007	NUM
dti-1334	469	19	.	.	PUNCT
dti-1334	470	1	proteomic	proteomic	ADJ
dti-1334	470	2	approaches	approach	NOUN
dti-1334	470	3	for	for	ADP
dti-1334	470	4	serum	serum	NOUN
dti-1334	470	5	biomarker	biomarker	NOUN
dti-1334	470	6	discovery	discovery	NOUN
dti-1334	470	7	in	in	ADP
dti-1334	470	8	cancer	cancer	NOUN
dti-1334	470	9	.	.	PUNCT
dti-1334	471	1	anticancer	anticancer	NOUN
dti-1334	471	2	res	re	NOUN
dti-1334	471	3	.	.	PROPN
dti-1334	471	4	,	,	PUNCT
dti-1334	471	5	27:1247–55	27:1247–55	NUM
dti-1334	471	6	.	.	PUNCT
dti-1334	472	1	mcanuff	mcanuff	NOUN
dti-1334	472	2	,	,	PUNCT
dti-1334	472	3	m.a	m.a	PROPN
dti-1334	472	4	.	.	PROPN
dti-1334	472	5	,	,	PUNCT
dti-1334	472	6	rettig	rettig	PROPN
dti-1334	472	7	,	,	PUNCT
dti-1334	472	8	g.r	g.r	PROPN
dti-1334	472	9	.	.	PROPN
dti-1334	472	10	and	and	CCONJ
dti-1334	472	11	rice	rice	PROPN
dti-1334	472	12	,	,	PUNCT
dti-1334	472	13	k.g	k.g	PROPN
dti-1334	472	14	.	.	PROPN
dti-1334	472	15	2007	2007	NUM
dti-1334	472	16	.	.	PUNCT
dti-1334	473	1	potency	potency	NOUN
dti-1334	473	2	of	of	ADP
dti-1334	473	3	sirna	sirna	PROPN
dti-1334	473	4	versus	versus	ADP
dti-1334	473	5	shrna	shrna	NOUN
dti-1334	473	6	mediated	mediate	VERB
dti-1334	473	7	knockdown	knockdown	NOUN
dti-1334	473	8	in	in	ADP
dti-1334	473	9	vivo	vivo	NOUN
dti-1334	473	10	.	.	PUNCT
dti-1334	474	1	j.	j.	PROPN
dti-1334	474	2	pharm	pharm	PROPN
dti-1334	474	3	sci	sci	PROPN
dti-1334	474	4	.	.	PROPN
dti-1334	474	5	,	,	PUNCT
dti-1334	474	6	96:2922–30	96:2922–30	NUM
dti-1334	474	7	.	.	PUNCT
dti-1334	475	1	meunier	meunier	PROPN
dti-1334	475	2	,	,	PUNCT
dti-1334	475	3	b.	b.	PROPN
dti-1334	475	4	,	,	PUNCT
dti-1334	475	5	dumas	dumas	PROPN
dti-1334	475	6	,	,	PUNCT
dti-1334	475	7	e.	e.	PROPN
dti-1334	475	8	,	,	PUNCT
dti-1334	475	9	piec	piec	PROPN
dti-1334	475	10	,	,	PUNCT
dti-1334	475	11	i.	i.	PROPN
dti-1334	475	12	,	,	PUNCT
dti-1334	475	13	bechet	bechet	PROPN
dti-1334	475	14	,	,	PUNCT
dti-1334	475	15	d.	d.	PROPN
dti-1334	475	16	,	,	PUNCT
dti-1334	475	17	hebraud	hebraud	INTJ
dti-1334	475	18	,	,	PUNCT
dti-1334	475	19	m.	m.	NOUN
dti-1334	475	20	and	and	CCONJ
dti-1334	475	21	hocquette	hocquette	NOUN
dti-1334	475	22	,	,	PUNCT
dti-1334	475	23	j.f	j.f	PROPN
dti-1334	475	24	.	.	PROPN
dti-1334	475	25	2007	2007	NUM
dti-1334	475	26	.	.	PUNCT
dti-1334	476	1	assessment	assessment	NOUN
dti-1334	476	2	of	of	ADP
dti-1334	476	3	hierarchical	hierarchical	ADJ
dti-1334	476	4	clustering	clustering	ADJ
dti-1334	476	5	methodologies	methodology	NOUN
dti-1334	476	6	for	for	ADP
dti-1334	476	7	proteomic	proteomic	ADJ
dti-1334	476	8	data	datum	NOUN
dti-1334	476	9	mining	mining	NOUN
dti-1334	476	10	.	.	PUNCT
dti-1334	477	1	j.	j.	PROPN
dti-1334	477	2	proteome	proteome	PROPN
dti-1334	477	3	res	res	PROPN
dti-1334	477	4	.	.	PUNCT
dti-1334	477	5	,	,	PUNCT
dti-1334	478	1	6:358–66	6:358–66	NOUN
dti-1334	478	2	.	.	PROPN
dti-1334	478	3	65	65	NUM
dti-1334	478	4	proteomics	proteomic	NOUN
dti-1334	478	5	in	in	ADP
dti-1334	478	6	personalized	personalized	ADJ
dti-1334	478	7	cancer	cancer	NOUN
dti-1334	478	8	therapy	therapy	NOUN
dti-1334	478	9	drug	drug	NOUN
dti-1334	478	10	target	target	NOUN
dti-1334	478	11	insights	insight	VERB
dti-1334	478	12	2008:3	2008:3	NUM
dti-1334	478	13	moseley	moseley	NOUN
dti-1334	478	14	,	,	PUNCT
dti-1334	478	15	m.a	m.a	PROPN
dti-1334	478	16	.	.	PROPN
dti-1334	478	17	2001	2001	NUM
dti-1334	478	18	.	.	PUNCT
dti-1334	479	1	current	current	ADJ
dti-1334	479	2	trends	trend	NOUN
dti-1334	479	3	in	in	ADP
dti-1334	479	4	differential	differential	ADJ
dti-1334	479	5	expression	expression	NOUN
dti-1334	479	6	proteomics	proteomic	NOUN
dti-1334	479	7	:	:	PUNCT
dti-1334	479	8	isotopically	isotopically	ADV
dti-1334	479	9	coded	code	VERB
dti-1334	479	10	tags	tag	NOUN
dti-1334	479	11	.	.	PUNCT
dti-1334	480	1	trends	trend	NOUN
dti-1334	480	2	biotechnol	biotechnol	VERB
dti-1334	480	3	.	.	PUNCT
dti-1334	481	1	,	,	PUNCT
dti-1334	481	2	19	19	NUM
dti-1334	481	3	:	:	PUNCT
dti-1334	481	4	s10–6	s10–6	PROPN
dti-1334	481	5	.	.	PUNCT
dti-1334	482	1	nagata	nagata	PROPN
dti-1334	482	2	,	,	PUNCT
dti-1334	482	3	y.	y.	PROPN
dti-1334	482	4	,	,	PUNCT
dti-1334	482	5	lan	lan	PROPN
dti-1334	482	6	,	,	PUNCT
dti-1334	482	7	k.h	k.h	PROPN
dti-1334	482	8	.	.	PROPN
dti-1334	482	9	,	,	PUNCT
dti-1334	482	10	zhou	zhou	PROPN
dti-1334	482	11	,	,	PUNCT
dti-1334	482	12	x.	x.	PROPN
dti-1334	482	13	,	,	PUNCT
dti-1334	482	14	tan	tan	PROPN
dti-1334	482	15	,	,	PUNCT
dti-1334	482	16	m.	m.	NOUN
dti-1334	482	17	,	,	PUNCT
dti-1334	482	18	esteva	esteva	PROPN
dti-1334	482	19	,	,	PUNCT
dti-1334	482	20	f.j	f.j	PROPN
dti-1334	482	21	.	.	PROPN
dti-1334	482	22	,	,	PUNCT
dti-1334	482	23	sahin	sahin	PROPN
dti-1334	482	24	,	,	PUNCT
dti-1334	482	25	a.a	a.a	PROPN
dti-1334	482	26	.	.	PROPN
dti-1334	482	27	,	,	PUNCT
dti-1334	482	28	klos	klos	PROPN
dti-1334	482	29	,	,	PUNCT
dti-1334	482	30	k.s	k.s	PROPN
dti-1334	482	31	.	.	PROPN
dti-1334	482	32	,	,	PUNCT
dti-1334	482	33	li	li	PROPN
dti-1334	482	34	,	,	PUNCT
dti-1334	482	35	p.	p.	PROPN
dti-1334	482	36	,	,	PUNCT
dti-1334	482	37	monia	monia	PROPN
dti-1334	482	38	,	,	PUNCT
dti-1334	482	39	b.p	b.p	PROPN
dti-1334	482	40	.	.	PROPN
dti-1334	482	41	,	,	PUNCT
dti-1334	482	42	nguyen	nguyen	PROPN
dti-1334	482	43	,	,	PUNCT
dti-1334	482	44	n.t	n.t	PROPN
dti-1334	482	45	.	.	PROPN
dti-1334	482	46	,	,	PUNCT
dti-1334	482	47	hortobagyi	hortobagyi	PROPN
dti-1334	482	48	,	,	PUNCT
dti-1334	482	49	g.n	g.n	PROPN
dti-1334	482	50	.	.	PROPN
dti-1334	482	51	,	,	PUNCT
dti-1334	482	52	hung	hung	PROPN
dti-1334	482	53	,	,	PUNCT
dti-1334	482	54	m.c	m.c	PROPN
dti-1334	482	55	.	.	PROPN
dti-1334	482	56	and	and	CCONJ
dti-1334	482	57	yu	yu	PROPN
dti-1334	482	58	,	,	PUNCT
dti-1334	482	59	d.	d.	PROPN
dti-1334	482	60	2004	2004	NUM
dti-1334	482	61	.	.	PUNCT
dti-1334	483	1	pten	pten	VERB
dti-1334	483	2	.	.	PUNCT
dti-1334	484	1	activation	activation	NOUN
dti-1334	484	2	contributes	contribute	VERB
dti-1334	484	3	to	to	ADP
dti-1334	484	4	tumor	tumor	NOUN
dti-1334	484	5	inhibition	inhibition	NOUN
dti-1334	484	6	by	by	ADP
dti-1334	484	7	trastuzumab	trastuzumab	NOUN
dti-1334	484	8	,	,	PUNCT
dti-1334	484	9	and	and	CCONJ
dti-1334	484	10	loss	loss	NOUN
dti-1334	484	11	of	of	ADP
dti-1334	484	12	pten	pten	NOUN
dti-1334	484	13	.	.	PUNCT
dti-1334	485	1	predicts	predict	VERB
dti-1334	485	2	trastuzumab	trastuzumab	NOUN
dti-1334	485	3	resistance	resistance	NOUN
dti-1334	485	4	in	in	ADP
dti-1334	485	5	patients	patient	NOUN
dti-1334	485	6	.	.	PUNCT
dti-1334	486	1	cancer	cancer	NOUN
dti-1334	486	2	cell	cell	NOUN
dti-1334	486	3	.	.	PUNCT
dti-1334	487	1	,	,	PUNCT
dti-1334	487	2	6:117–27	6:117–27	NOUN
dti-1334	487	3	.	.	PUNCT
dti-1334	488	1	nemunaitis	nemunaitis	PROPN
dti-1334	488	2	,	,	PUNCT
dti-1334	488	3	j.	j.	PROPN
dti-1334	488	4	,	,	PUNCT
dti-1334	488	5	senzer	senzer	NOUN
dti-1334	488	6	,	,	PUNCT
dti-1334	488	7	n.	n.	PROPN
dti-1334	488	8	,	,	PUNCT
dti-1334	488	9	khalil	khalil	PROPN
dti-1334	488	10	,	,	PUNCT
dti-1334	488	11	i.	i.	PROPN
dti-1334	488	12	,	,	PUNCT
dti-1334	488	13	shen	shen	PROPN
dti-1334	488	14	,	,	PUNCT
dti-1334	488	15	y.	y.	PROPN
dti-1334	488	16	,	,	PUNCT
dti-1334	488	17	kumar	kumar	PROPN
dti-1334	488	18	,	,	PUNCT
dti-1334	488	19	p.	p.	PROPN
dti-1334	488	20	,	,	PUNCT
dti-1334	488	21	tong	tong	PROPN
dti-1334	488	22	,	,	PUNCT
dti-1334	488	23	a.	a.	PROPN
dti-1334	488	24	,	,	PUNCT
dti-1334	488	25	kuhn	kuhn	PROPN
dti-1334	488	26	,	,	PUNCT
dti-1334	488	27	j.	j.	PROPN
dti-1334	488	28	,	,	PUNCT
dti-1334	488	29	lamont	lamont	PROPN
dti-1334	488	30	,	,	PUNCT
dti-1334	488	31	j.	j.	PROPN
dti-1334	488	32	,	,	PUNCT
dti-1334	488	33	nemunaitis	nemunaitis	PROPN
dti-1334	488	34	,	,	PUNCT
dti-1334	488	35	m.	m.	NOUN
dti-1334	488	36	,	,	PUNCT
dti-1334	488	37	rao	rao	PROPN
dti-1334	488	38	,	,	PUNCT
dti-1334	488	39	d.	d.	PROPN
dti-1334	488	40	,	,	PUNCT
dti-1334	488	41	zhang	zhang	PROPN
dti-1334	488	42	,	,	PUNCT
dti-1334	488	43	y.a	y.a	PROPN
dti-1334	488	44	.	.	PROPN
dti-1334	488	45	,	,	PUNCT
dti-1334	488	46	zhou	zhou	PROPN
dti-1334	488	47	,	,	PUNCT
dti-1334	488	48	y.	y.	PROPN
dti-1334	488	49	,	,	PUNCT
dti-1334	488	50	vorhies	vorhie	NOUN
dti-1334	488	51	,	,	PUNCT
dti-1334	488	52	j.	j.	PROPN
dti-1334	488	53	,	,	PUNCT
dti-1334	488	54	maples	maple	NOUN
dti-1334	488	55	,	,	PUNCT
dti-1334	488	56	p.	p.	NOUN
dti-1334	488	57	,	,	PUNCT
dti-1334	488	58	hill	hill	PROPN
dti-1334	488	59	,	,	PUNCT
dti-1334	488	60	c.	c.	PROPN
dti-1334	488	61	and	and	CCONJ
dti-1334	488	62	shanahan	shanahan	PROPN
dti-1334	488	63	,	,	PUNCT
dti-1334	488	64	d.	d.	PROPN
dti-1334	488	65	2007	2007	NUM
dti-1334	488	66	.	.	PUNCT
dti-1334	489	1	proof	proof	NOUN
dti-1334	489	2	concept	concept	NOUN
dti-1334	489	3	for	for	ADP
dti-1334	489	4	clinical	clinical	ADJ
dti-1334	489	5	justifi	justifi	NOUN
dti-1334	489	6	cation	cation	NOUN
dti-1334	489	7	of	of	ADP
dti-1334	489	8	network	network	NOUN
dti-1334	489	9	mapping	mapping	NOUN
dti-1334	489	10	for	for	ADP
dti-1334	489	11	personalized	personalized	ADJ
dti-1334	489	12	cancer	cancer	NOUN
dti-1334	489	13	therapeutics	therapeutic	NOUN
dti-1334	489	14	.	.	PUNCT
dti-1334	490	1	cancer	cancer	NOUN
dti-1334	490	2	gene	gene	NOUN
dti-1334	490	3	ther	ther	ADV
dti-1334	490	4	.	.	PUNCT
dti-1334	491	1	,	,	PUNCT
dti-1334	491	2	14:686–95	14:686–95	NOUN
dti-1334	491	3	.	.	PUNCT
dti-1334	492	1	overall	overall	ADJ
dti-1334	492	2	,	,	PUNCT
dti-1334	492	3	c.m	c.m	PROPN
dti-1334	492	4	.	.	PROPN
dti-1334	492	5	and	and	CCONJ
dti-1334	492	6	dean	dean	PROPN
dti-1334	492	7	,	,	PUNCT
dti-1334	492	8	r.a	r.a	PROPN
dti-1334	492	9	.	.	PROPN
dti-1334	492	10	2006	2006	NUM
dti-1334	492	11	.	.	PUNCT
dti-1334	493	1	degradomics	degradomic	NOUN
dti-1334	493	2	:	:	PUNCT
dti-1334	493	3	systems	system	NOUN
dti-1334	493	4	biology	biology	NOUN
dti-1334	493	5	of	of	ADP
dti-1334	493	6	the	the	DET
dti-1334	493	7	protease	protease	NOUN
dti-1334	493	8	web	web	NOUN
dti-1334	493	9	.	.	PUNCT
dti-1334	493	10	pleiotropic	pleiotropic	ADJ
dti-1334	493	11	roles	role	NOUN
dti-1334	493	12	of	of	ADP
dti-1334	493	13	mmps	mmp	NOUN
dti-1334	493	14	in	in	ADP
dti-1334	493	15	cancer	cancer	NOUN
dti-1334	493	16	.	.	PUNCT
dti-1334	494	1	cancer	cancer	NOUN
dti-1334	494	2	metastasis	metastasis	NOUN
dti-1334	494	3	rev	rev	VERB
dti-1334	494	4	.	.	PROPN
dti-1334	494	5	,	,	PUNCT
dti-1334	494	6	25:69–75	25:69–75	NUM
dti-1334	494	7	.	.	PUNCT
dti-1334	495	1	palagi	palagi	PROPN
dti-1334	495	2	,	,	PUNCT
dti-1334	495	3	p.m.	p.m.	PROPN
dti-1334	495	4	,	,	PUNCT
dti-1334	495	5	hernandez	hernandez	PROPN
dti-1334	495	6	,	,	PUNCT
dti-1334	495	7	p.	p.	NOUN
dti-1334	495	8	,	,	PUNCT
dti-1334	495	9	walther	walther	NOUN
dti-1334	495	10	,	,	PUNCT
dti-1334	495	11	d.	d.	PROPN
dti-1334	495	12	and	and	CCONJ
dti-1334	495	13	appel	appel	PROPN
dti-1334	495	14	,	,	PUNCT
dti-1334	495	15	r.d	r.d	PROPN
dti-1334	495	16	.	.	PROPN
dti-1334	495	17	2006	2006	NUM
dti-1334	495	18	.	.	PUNCT
dti-1334	496	1	proteome	proteome	PROPN
dti-1334	496	2	informatics	informatics	PROPN
dti-1334	496	3	i	i	PRON
dti-1334	496	4	:	:	PUNCT
dti-1334	496	5	bioinformatics	bioinformatics	NOUN
dti-1334	496	6	tools	tool	NOUN
dti-1334	496	7	for	for	ADP
dti-1334	496	8	processing	process	VERB
dti-1334	496	9	experimental	experimental	ADJ
dti-1334	496	10	data	datum	NOUN
dti-1334	496	11	.	.	PUNCT
dti-1334	497	1	proteomics	proteomic	NOUN
dti-1334	497	2	,	,	PUNCT
dti-1334	497	3	6:5435–44	6:5435–44	NUM
dti-1334	497	4	.	.	PUNCT
dti-1334	498	1	pearl	pearl	PROPN
dti-1334	498	2	,	,	PUNCT
dti-1334	498	3	j.	j.	PROPN
dti-1334	498	4	2000	2000	NUM
dti-1334	498	5	.	.	PUNCT
dti-1334	499	1	causality	causality	NOUN
dti-1334	499	2	:	:	PUNCT
dti-1334	499	3	models	model	NOUN
dti-1334	499	4	,	,	PUNCT
dti-1334	499	5	reasoning	reasoning	NOUN
dti-1334	499	6	,	,	PUNCT
dti-1334	499	7	and	and	CCONJ
dti-1334	499	8	inference	inference	NOUN
dti-1334	499	9	.	.	PUNCT
dti-1334	500	1	new	new	PROPN
dti-1334	500	2	york	york	PROPN
dti-1334	500	3	,	,	PUNCT
dti-1334	500	4	cambridge	cambridge	PROPN
dti-1334	500	5	university	university	PROPN
dti-1334	500	6	press	press	NOUN
dti-1334	500	7	:	:	PUNCT
dti-1334	501	1	cambridge	cambridge	PROPN
dti-1334	501	2	,	,	PUNCT
dti-1334	501	3	u.k	u.k	PROPN
dti-1334	501	4	.	.	PROPN
dti-1334	501	5	perou	perou	PROPN
dti-1334	501	6	,	,	PUNCT
dti-1334	501	7	c.m	c.m	PROPN
dti-1334	501	8	.	.	PROPN
dti-1334	501	9	,	,	PUNCT
dti-1334	501	10	sorlie	sorlie	PROPN
dti-1334	501	11	,	,	PUNCT
dti-1334	501	12	t.	t.	PROPN
dti-1334	501	13	,	,	PUNCT
dti-1334	501	14	eisen	eisen	PROPN
dti-1334	501	15	,	,	PUNCT
dti-1334	501	16	m.b	m.b	PROPN
dti-1334	501	17	.	.	PROPN
dti-1334	501	18	,	,	PUNCT
dti-1334	501	19	van	van	PROPN
dti-1334	501	20	de	de	PROPN
dti-1334	501	21	rijn	rijn	PROPN
dti-1334	501	22	,	,	PUNCT
dti-1334	501	23	m.	m.	NOUN
dti-1334	501	24	,	,	PUNCT
dti-1334	501	25	jeffrey	jeffrey	PROPN
dti-1334	501	26	,	,	PUNCT
dti-1334	501	27	s.s	s.s	PROPN
dti-1334	501	28	.	.	PROPN
dti-1334	501	29	,	,	PUNCT
dti-1334	501	30	rees	rees	PROPN
dti-1334	501	31	,	,	PUNCT
dti-1334	501	32	c.a	c.a	PROPN
dti-1334	501	33	.	.	PROPN
dti-1334	501	34	,	,	PUNCT
dti-1334	501	35	pollack	pollack	PROPN
dti-1334	501	36	,	,	PUNCT
dti-1334	501	37	j.r	j.r	PROPN
dti-1334	501	38	.	.	PROPN
dti-1334	501	39	,	,	PUNCT
dti-1334	501	40	ross	ross	PROPN
dti-1334	501	41	,	,	PUNCT
dti-1334	501	42	d.t	d.t	PROPN
dti-1334	501	43	.	.	PROPN
dti-1334	501	44	,	,	PUNCT
dti-1334	501	45	johnsen	johnsen	PROPN
dti-1334	501	46	,	,	PUNCT
dti-1334	501	47	h.	h.	PROPN
dti-1334	501	48	,	,	PUNCT
dti-1334	501	49	akslen	akslen	PROPN
dti-1334	501	50	,	,	PUNCT
dti-1334	501	51	l.a	l.a	PROPN
dti-1334	501	52	.	.	PROPN
dti-1334	501	53	,	,	PUNCT
dti-1334	501	54	fluge	fluge	VERB
dti-1334	501	55	,	,	PUNCT
dti-1334	501	56	o.	o.	PROPN
dti-1334	501	57	,	,	PUNCT
dti-1334	501	58	pergamenschikov	pergamenschikov	PROPN
dti-1334	501	59	,	,	PUNCT
dti-1334	501	60	a.	a.	PROPN
dti-1334	501	61	,	,	PUNCT
dti-1334	501	62	williams	williams	PROPN
dti-1334	501	63	,	,	PUNCT
dti-1334	501	64	c.	c.	PROPN
dti-1334	501	65	,	,	PUNCT
dti-1334	501	66	zhu	zhu	PROPN
dti-1334	501	67	,	,	PUNCT
dti-1334	501	68	s.x	s.x	PROPN
dti-1334	501	69	.	.	PROPN
dti-1334	501	70	,	,	PUNCT
dti-1334	501	71	lonning	lonning	NOUN
dti-1334	501	72	,	,	PUNCT
dti-1334	501	73	p.e	p.e	PROPN
dti-1334	501	74	.	.	PROPN
dti-1334	501	75	,	,	PUNCT
dti-1334	501	76	borresen	borresen	PROPN
dti-1334	501	77	-	-	PUNCT
dti-1334	501	78	dale	dale	NOUN
dti-1334	501	79	,	,	PUNCT
dti-1334	501	80	a.l	a.l	PROPN
dti-1334	501	81	.	.	PROPN
dti-1334	501	82	,	,	PUNCT
dti-1334	501	83	brown	brown	PROPN
dti-1334	501	84	,	,	PUNCT
dti-1334	501	85	p.o	p.o	PROPN
dti-1334	501	86	.	.	PROPN
dti-1334	501	87	and	and	CCONJ
dti-1334	501	88	botstein	botstein	ADJ
dti-1334	501	89	,	,	PUNCT
dti-1334	501	90	d.	d.	PROPN
dti-1334	501	91	2000	2000	NUM
dti-1334	501	92	.	.	PUNCT
dti-1334	502	1	molecular	molecular	ADJ
dti-1334	502	2	portraits	portrait	NOUN
dti-1334	502	3	of	of	ADP
dti-1334	502	4	human	human	ADJ
dti-1334	502	5	breast	breast	NOUN
dti-1334	502	6	tumours	tumour	NOUN
dti-1334	502	7	.	.	PUNCT
dti-1334	503	1	nature	nature	NOUN
dti-1334	503	2	,	,	PUNCT
dti-1334	503	3	406:747–52	406:747–52	PROPN
dti-1334	503	4	.	.	PUNCT
dti-1334	503	5	petricoin	petricoin	PROPN
dti-1334	503	6	,	,	PUNCT
dti-1334	503	7	e.	e.	PROPN
dti-1334	503	8	,	,	PUNCT
dti-1334	503	9	wulfkuhle	wulfkuhle	PROPN
dti-1334	503	10	,	,	PUNCT
dti-1334	503	11	j.	j.	PROPN
dti-1334	503	12	,	,	PUNCT
dti-1334	503	13	espina	espina	PROPN
dti-1334	503	14	,	,	PUNCT
dti-1334	503	15	v.	v.	PROPN
dti-1334	503	16	and	and	CCONJ
dti-1334	503	17	liotta	liotta	PROPN
dti-1334	503	18	,	,	PUNCT
dti-1334	503	19	l.a	l.a	PROPN
dti-1334	503	20	.	.	PROPN
dti-1334	503	21	2004	2004	NUM
dti-1334	503	22	.	.	PUNCT
dti-1334	504	1	clinical	clinical	ADJ
dti-1334	504	2	proteomics	proteomic	NOUN
dti-1334	504	3	:	:	PUNCT
dti-1334	504	4	revolutionizing	revolutionize	VERB
dti-1334	504	5	disease	disease	NOUN
dti-1334	504	6	detection	detection	NOUN
dti-1334	504	7	and	and	CCONJ
dti-1334	504	8	patient	patient	ADJ
dti-1334	504	9	tailoring	tailoring	NOUN
dti-1334	504	10	therapy	therapy	NOUN
dti-1334	504	11	.	.	PUNCT
dti-1334	505	1	j.	j.	PROPN
dti-1334	505	2	proteome	proteome	PROPN
dti-1334	505	3	res	res	PROPN
dti-1334	505	4	.	.	PROPN
dti-1334	505	5	,	,	PUNCT
dti-1334	506	1	3:209–17	3:209–17	NUM
dti-1334	506	2	.	.	PUNCT
dti-1334	506	3	poon	poon	NOUN
dti-1334	506	4	,	,	PUNCT
dti-1334	506	5	t.c	t.c	PROPN
dti-1334	506	6	.	.	PROPN
dti-1334	506	7	2007	2007	NUM
dti-1334	506	8	.	.	PUNCT
dti-1334	507	1	opportunities	opportunity	NOUN
dti-1334	507	2	and	and	CCONJ
dti-1334	507	3	limitations	limitation	NOUN
dti-1334	507	4	of	of	ADP
dti-1334	507	5	seldi	seldi	PROPN
dti-1334	507	6	-	-	PUNCT
dti-1334	507	7	tof	tof	PROPN
dti-1334	507	8	-	-	PUNCT
dti-1334	507	9	ms	ms	NOUN
dti-1334	507	10	in	in	ADP
dti-1334	507	11	biomedical	biomedical	ADJ
dti-1334	507	12	research	research	NOUN
dti-1334	507	13	:	:	PUNCT
dti-1334	507	14	practical	practical	ADJ
dti-1334	507	15	advices	advice	NOUN
dti-1334	507	16	.	.	PUNCT
dti-1334	508	1	expert	expert	NOUN
dti-1334	508	2	rev	rev	PROPN
dti-1334	508	3	.	.	PROPN
dti-1334	508	4	proteomics	proteomic	NOUN
dti-1334	508	5	,	,	PUNCT
dti-1334	508	6	4:51–65	4:51–65	NUM
dti-1334	508	7	.	.	PUNCT
dti-1334	509	1	rathsam	rathsam	PROPN
dti-1334	509	2	,	,	PUNCT
dti-1334	509	3	c.	c.	PROPN
dti-1334	509	4	,	,	PUNCT
dti-1334	509	5	eaton	eaton	PROPN
dti-1334	509	6	,	,	PUNCT
dti-1334	509	7	r.e	r.e	PROPN
dti-1334	509	8	.	.	PROPN
dti-1334	509	9	,	,	PUNCT
dti-1334	509	10	simpson	simpson	PROPN
dti-1334	509	11	,	,	PUNCT
dti-1334	509	12	c.l	c.l	PROPN
dti-1334	509	13	.	.	PROPN
dti-1334	509	14	,	,	PUNCT
dti-1334	509	15	browne	browne	PROPN
dti-1334	509	16	,	,	PUNCT
dti-1334	509	17	g.v	g.v	PROPN
dti-1334	509	18	.	.	PROPN
dti-1334	509	19	,	,	PUNCT
dti-1334	509	20	valova	valova	PROPN
dti-1334	509	21	,	,	PUNCT
dti-1334	509	22	v.a	v.a	PROPN
dti-1334	509	23	.	.	PROPN
dti-1334	509	24	,	,	PUNCT
dti-1334	509	25	harty	harty	PROPN
dti-1334	509	26	,	,	PUNCT
dti-1334	509	27	d.w	d.w	PROPN
dti-1334	509	28	.	.	PROPN
dti-1334	509	29	and	and	CCONJ
dti-1334	509	30	jacques	jacques	PROPN
dti-1334	509	31	,	,	PUNCT
dti-1334	509	32	n.a	n.a	PROPN
dti-1334	509	33	.	.	PROPN
dti-1334	509	34	2005	2005	NUM
dti-1334	509	35	.	.	PUNCT
dti-1334	510	1	two	two	NUM
dti-1334	510	2	-	-	PUNCT
dti-1334	510	3	dimensional	dimensional	ADJ
dti-1334	510	4	fl	fl	NOUN
dti-1334	510	5	uorescence	uorescence	NOUN
dti-1334	510	6	difference	difference	NOUN
dti-1334	510	7	gel	gel	NOUN
dti-1334	510	8	electrophoretic	electrophoretic	NOUN
dti-1334	510	9	analysis	analysis	NOUN
dti-1334	510	10	of	of	ADP
dti-1334	510	11	streptococcus	streptococcus	NOUN
dti-1334	510	12	mutans	mutan	NOUN
dti-1334	510	13	biofi	biofi	NOUN
dti-1334	510	14	lms	lm	NOUN
dti-1334	510	15	.	.	PUNCT
dti-1334	511	1	j.	j.	PROPN
dti-1334	511	2	proteome	proteome	PROPN
dti-1334	511	3	res	res	PROPN
dti-1334	511	4	.	.	PROPN
dti-1334	511	5	,	,	PUNCT
dti-1334	511	6	4:2161–73	4:2161–73	PROPN
dti-1334	511	7	.	.	PUNCT
dti-1334	512	1	reid	reid	PROPN
dti-1334	512	2	,	,	PUNCT
dti-1334	512	3	j.d	j.d	PROPN
dti-1334	512	4	.	.	PROPN
dti-1334	512	5	,	,	PUNCT
dti-1334	512	6	parker	parker	PROPN
dti-1334	512	7	,	,	PUNCT
dti-1334	512	8	c.e	c.e	PROPN
dti-1334	512	9	.	.	PROPN
dti-1334	512	10	and	and	CCONJ
dti-1334	512	11	borchers	borcher	NOUN
dti-1334	512	12	,	,	PUNCT
dti-1334	512	13	c.h	c.h	PROPN
dti-1334	512	14	.	.	PROPN
dti-1334	512	15	2007	2007	NUM
dti-1334	512	16	.	.	PUNCT
dti-1334	513	1	protein	protein	NOUN
dti-1334	513	2	arrays	array	VERB
dti-1334	513	3	for	for	ADP
dti-1334	513	4	biomarker	biomarker	NOUN
dti-1334	513	5	discovery	discovery	NOUN
dti-1334	513	6	.	.	PUNCT
dti-1334	514	1	curr	curr	PROPN
dti-1334	514	2	.	.	PUNCT
dti-1334	515	1	opin	opin	NOUN
dti-1334	515	2	.	.	PUNCT
dti-1334	516	1	mol	mol	PROPN
dti-1334	516	2	.	.	PROPN
dti-1334	517	1	ther	ther	PROPN
dti-1334	517	2	.	.	PUNCT
dti-1334	517	3	,	,	PUNCT
dti-1334	518	1	9:216–21	9:216–21	PROPN
dti-1334	518	2	.	.	PUNCT
dti-1334	519	1	reynolds	reynolds	PROPN
dti-1334	519	2	,	,	PUNCT
dti-1334	519	3	j.l	j.l	PROPN
dti-1334	519	4	.	.	PROPN
dti-1334	519	5	,	,	PUNCT
dti-1334	519	6	mahajan	mahajan	PROPN
dti-1334	519	7	,	,	PUNCT
dti-1334	519	8	s.d	s.d	PROPN
dti-1334	519	9	.	.	PROPN
dti-1334	519	10	,	,	PUNCT
dti-1334	519	11	sykes	sykes	PROPN
dti-1334	519	12	,	,	PUNCT
dti-1334	519	13	d.e	d.e	PROPN
dti-1334	519	14	.	.	PROPN
dti-1334	519	15	,	,	PUNCT
dti-1334	519	16	schwartz	schwartz	PROPN
dti-1334	519	17	,	,	PUNCT
dti-1334	519	18	s.a	s.a	PROPN
dti-1334	519	19	.	.	PROPN
dti-1334	519	20	and	and	CCONJ
dti-1334	519	21	nair	nair	PROPN
dti-1334	519	22	,	,	PUNCT
dti-1334	519	23	m.p	m.p	PROPN
dti-1334	519	24	.	.	PROPN
dti-1334	519	25	2007	2007	NUM
dti-1334	519	26	.	.	PUNCT
dti-1334	520	1	proteomic	proteomic	ADJ
dti-1334	520	2	analyses	analysis	NOUN
dti-1334	520	3	of	of	ADP
dti-1334	520	4	methamphetamine	methamphetamine	NOUN
dti-1334	520	5	(	(	PUNCT
dti-1334	520	6	meth)-induced	meth)-induce	VERB
dti-1334	520	7	differential	differential	ADJ
dti-1334	520	8	protein	protein	NOUN
dti-1334	520	9	expression	expression	NOUN
dti-1334	520	10	by	by	ADP
dti-1334	520	11	immature	immature	ADJ
dti-1334	520	12	dendritic	dendritic	ADJ
dti-1334	520	13	cells	cell	NOUN
dti-1334	520	14	(	(	PUNCT
dti-1334	520	15	idc	idc	PROPN
dti-1334	520	16	)	)	PUNCT
dti-1334	520	17	.	.	PUNCT
dti-1334	521	1	biochim	biochim	PROPN
dti-1334	521	2	.	.	PUNCT
dti-1334	522	1	biophys	biophy	NOUN
dti-1334	522	2	.	.	PUNCT
dti-1334	523	1	acta	acta	PROPN
dti-1334	523	2	.	.	PROPN
dti-1334	523	3	,	,	PUNCT
dti-1334	523	4	1774:433–42	1774:433–42	NUM
dti-1334	523	5	.	.	PUNCT
dti-1334	523	6	roelofsen	roelofsen	VERB
dti-1334	523	7	,	,	PUNCT
dti-1334	523	8	h.	h.	PROPN
dti-1334	523	9	,	,	PUNCT
dti-1334	523	10	alvarez	alvarez	PROPN
dti-1334	523	11	-	-	PUNCT
dti-1334	523	12	llamas	llamas	PROPN
dti-1334	523	13	,	,	PUNCT
dti-1334	523	14	g.	g.	PROPN
dti-1334	523	15	,	,	PUNCT
dti-1334	523	16	schepers	scheper	NOUN
dti-1334	523	17	,	,	PUNCT
dti-1334	523	18	m.	m.	NOUN
dti-1334	523	19	,	,	PUNCT
dti-1334	523	20	landman	landman	NOUN
dti-1334	523	21	,	,	PUNCT
dti-1334	523	22	k.	k.	PROPN
dti-1334	523	23	and	and	CCONJ
dti-1334	523	24	vonk	vonk	PROPN
dti-1334	523	25	,	,	PUNCT
dti-1334	523	26	r.j	r.j	PROPN
dti-1334	523	27	.	.	PROPN
dti-1334	523	28	2007	2007	NUM
dti-1334	523	29	.	.	PUNCT
dti-1334	524	1	proteomics	proteomic	NOUN
dti-1334	524	2	profi	profi	PROPN
dti-1334	524	3	ling	ling	PROPN
dti-1334	524	4	of	of	ADP
dti-1334	524	5	urine	urine	NOUN
dti-1334	524	6	with	with	ADP
dti-1334	524	7	surface	surface	NOUN
dti-1334	524	8	enhanced	enhance	VERB
dti-1334	524	9	laser	laser	NOUN
dti-1334	524	10	desorption	desorption	NOUN
dti-1334	524	11	/	/	SYM
dti-1334	524	12	ionization	ionization	NOUN
dti-1334	524	13	time	time	NOUN
dti-1334	524	14	of	of	ADP
dti-1334	524	15	fl	fl	NUM
dti-1334	524	16	ight	ight	ADJ
dti-1334	524	17	mass	mass	ADJ
dti-1334	524	18	spectrometry	spectrometry	NOUN
dti-1334	524	19	.	.	PUNCT
dti-1334	525	1	proteome	proteome	PROPN
dti-1334	525	2	sci	sci	PROPN
dti-1334	525	3	.	.	PROPN
dti-1334	525	4	,	,	PUNCT
dti-1334	525	5	5:2	5:2	NUM
dti-1334	525	6	.	.	PUNCT
dti-1334	526	1	rosenwald	rosenwald	NOUN
dti-1334	526	2	,	,	PUNCT
dti-1334	526	3	a.	a.	PROPN
dti-1334	526	4	,	,	PUNCT
dti-1334	526	5	wright	wright	PROPN
dti-1334	526	6	,	,	PUNCT
dti-1334	526	7	g.	g.	PROPN
dti-1334	526	8	,	,	PUNCT
dti-1334	526	9	chan	chan	PROPN
dti-1334	526	10	,	,	PUNCT
dti-1334	526	11	w.c	w.c	PROPN
dti-1334	526	12	.	.	PROPN
dti-1334	526	13	,	,	PUNCT
dti-1334	526	14	connors	connor	NOUN
dti-1334	526	15	,	,	PUNCT
dti-1334	526	16	j.m	j.m	PROPN
dti-1334	526	17	.	.	PROPN
dti-1334	526	18	,	,	PUNCT
dti-1334	526	19	campo	campo	PROPN
dti-1334	526	20	,	,	PUNCT
dti-1334	526	21	e.	e.	PROPN
dti-1334	526	22	,	,	PUNCT
dti-1334	526	23	fisher	fisher	PROPN
dti-1334	526	24	,	,	PUNCT
dti-1334	526	25	r.i	r.i	PROPN
dti-1334	526	26	.	.	PROPN
dti-1334	526	27	,	,	PUNCT
dti-1334	526	28	gascoyne	gascoyne	PROPN
dti-1334	526	29	,	,	PUNCT
dti-1334	526	30	r.d	r.d	PROPN
dti-1334	526	31	.	.	PROPN
dti-1334	526	32	,	,	PUNCT
dti-1334	526	33	muller	muller	NOUN
dti-1334	526	34	-	-	PUNCT
dti-1334	526	35	hermelink	hermelink	PROPN
dti-1334	526	36	,	,	PUNCT
dti-1334	526	37	h.k	h.k	PROPN
dti-1334	526	38	.	.	PROPN
dti-1334	526	39	,	,	PUNCT
dti-1334	526	40	smeland	smeland	NOUN
dti-1334	526	41	,	,	PUNCT
dti-1334	526	42	e.b	e.b	PROPN
dti-1334	526	43	.	.	PROPN
dti-1334	526	44	,	,	PUNCT
dti-1334	527	1	giltnane	giltnane	PROPN
dti-1334	527	2	,	,	PUNCT
dti-1334	527	3	j.m	j.m	PROPN
dti-1334	527	4	.	.	PROPN
dti-1334	527	5	,	,	PUNCT
dti-1334	527	6	hurt	hurt	VERB
dti-1334	527	7	,	,	PUNCT
dti-1334	527	8	e.m	e.m	PROPN
dti-1334	527	9	.	.	PROPN
dti-1334	527	10	,	,	PUNCT
dti-1334	527	11	zhao	zhao	PROPN
dti-1334	527	12	,	,	PUNCT
dti-1334	527	13	h.	h.	PROPN
dti-1334	527	14	,	,	PUNCT
dti-1334	527	15	averett	averett	PROPN
dti-1334	527	16	,	,	PUNCT
dti-1334	527	17	l.	l.	PROPN
dti-1334	527	18	,	,	PUNCT
dti-1334	527	19	yang	yang	PROPN
dti-1334	527	20	,	,	PUNCT
dti-1334	527	21	l.	l.	PROPN
dti-1334	527	22	,	,	PUNCT
dti-1334	527	23	wilson	wilson	PROPN
dti-1334	527	24	,	,	PUNCT
dti-1334	527	25	w.h	w.h	PROPN
dti-1334	527	26	.	.	PROPN
dti-1334	527	27	,	,	PUNCT
dti-1334	527	28	jaffe	jaffe	PROPN
dti-1334	527	29	,	,	PUNCT
dti-1334	527	30	e.s	e.s	PROPN
dti-1334	527	31	.	.	PROPN
dti-1334	527	32	,	,	PUNCT
dti-1334	527	33	simon	simon	PROPN
dti-1334	527	34	,	,	PUNCT
dti-1334	527	35	r.	r.	PROPN
dti-1334	527	36	,	,	PUNCT
dti-1334	527	37	klausner	klausner	PROPN
dti-1334	527	38	,	,	PUNCT
dti-1334	527	39	r.d	r.d	PROPN
dti-1334	527	40	.	.	PROPN
dti-1334	527	41	,	,	PUNCT
dti-1334	527	42	powell	powell	PROPN
dti-1334	527	43	,	,	PUNCT
dti-1334	527	44	j.	j.	PROPN
dti-1334	527	45	,	,	PUNCT
dti-1334	527	46	duffey	duffey	PROPN
dti-1334	527	47	,	,	PUNCT
dti-1334	527	48	p.l	p.l	PROPN
dti-1334	527	49	.	.	PROPN
dti-1334	527	50	,	,	PUNCT
dti-1334	527	51	longo	longo	PROPN
dti-1334	527	52	,	,	PUNCT
dti-1334	527	53	d.l	d.l	PROPN
dti-1334	527	54	.	.	PROPN
dti-1334	527	55	,	,	PUNCT
dti-1334	527	56	greiner	greiner	PROPN
dti-1334	527	57	,	,	PUNCT
dti-1334	527	58	t.c	t.c	PROPN
dti-1334	527	59	.	.	PROPN
dti-1334	527	60	,	,	PUNCT
dti-1334	527	61	weisenburger	weisenburger	NOUN
dti-1334	527	62	,	,	PUNCT
dti-1334	527	63	d.d	d.d	PROPN
dti-1334	527	64	.	.	PROPN
dti-1334	527	65	,	,	PUNCT
dti-1334	527	66	sanger	sanger	PROPN
dti-1334	527	67	,	,	PUNCT
dti-1334	527	68	w.g	w.g	PROPN
dti-1334	527	69	.	.	PROPN
dti-1334	527	70	,	,	PUNCT
dti-1334	527	71	dave	dave	PROPN
dti-1334	527	72	,	,	PUNCT
dti-1334	527	73	b.j	b.j	PROPN
dti-1334	527	74	.	.	PROPN
dti-1334	527	75	,	,	PUNCT
dti-1334	527	76	lynch	lynch	PROPN
dti-1334	527	77	,	,	PUNCT
dti-1334	527	78	j.c	j.c	PROPN
dti-1334	527	79	.	.	PROPN
dti-1334	527	80	,	,	PUNCT
dti-1334	527	81	vose	vose	PROPN
dti-1334	527	82	,	,	PUNCT
dti-1334	527	83	j.	j.	PROPN
dti-1334	527	84	,	,	PUNCT
dti-1334	527	85	armitage	armitage	PROPN
dti-1334	527	86	,	,	PUNCT
dti-1334	527	87	j.o	j.o	PROPN
dti-1334	527	88	.	.	PROPN
dti-1334	527	89	,	,	PUNCT
dti-1334	527	90	montserrat	montserrat	PROPN
dti-1334	527	91	,	,	PUNCT
dti-1334	527	92	e.	e.	PROPN
dti-1334	527	93	,	,	PUNCT
dti-1334	527	94	lopez	lopez	PROPN
dti-1334	527	95	-	-	PUNCT
dti-1334	527	96	guillermo	guillermo	PROPN
dti-1334	527	97	,	,	PUNCT
dti-1334	527	98	a.	a.	PROPN
dti-1334	527	99	,	,	PUNCT
dti-1334	527	100	grogan	grogan	PROPN
dti-1334	527	101	,	,	PUNCT
dti-1334	527	102	t.m	t.m	PROPN
dti-1334	527	103	.	.	PROPN
dti-1334	527	104	,	,	PUNCT
dti-1334	527	105	miller	miller	PROPN
dti-1334	527	106	,	,	PUNCT
dti-1334	527	107	t.p	t.p	PROPN
dti-1334	527	108	.	.	PROPN
dti-1334	527	109	,	,	PUNCT
dti-1334	527	110	leblanc	leblanc	PROPN
dti-1334	527	111	,	,	PUNCT
dti-1334	527	112	m.	m.	NOUN
dti-1334	527	113	,	,	PUNCT
dti-1334	527	114	ott	ott	PROPN
dti-1334	527	115	,	,	PUNCT
dti-1334	527	116	g.	g.	PROPN
dti-1334	527	117	,	,	PUNCT
dti-1334	527	118	kvaloy	kvaloy	PROPN
dti-1334	527	119	,	,	PUNCT
dti-1334	527	120	s.	s.	PROPN
dti-1334	527	121	,	,	PUNCT
dti-1334	527	122	delabie	delabie	PROPN
dti-1334	527	123	,	,	PUNCT
dti-1334	527	124	j.	j.	PROPN
dti-1334	527	125	,	,	PUNCT
dti-1334	527	126	holte	holte	PROPN
dti-1334	527	127	,	,	PUNCT
dti-1334	527	128	h.	h.	PROPN
dti-1334	527	129	,	,	PUNCT
dti-1334	527	130	krajci	krajci	PROPN
dti-1334	527	131	,	,	PUNCT
dti-1334	527	132	p.	p.	NOUN
dti-1334	527	133	,	,	PUNCT
dti-1334	527	134	stokke	stokke	NOUN
dti-1334	527	135	,	,	PUNCT
dti-1334	527	136	t.	t.	NOUN
dti-1334	527	137	and	and	CCONJ
dti-1334	527	138	staudt	staudt	NOUN
dti-1334	527	139	,	,	PUNCT
dti-1334	527	140	l.m	l.m	PROPN
dti-1334	527	141	.	.	PROPN
dti-1334	527	142	2002	2002	NUM
dti-1334	527	143	.	.	PUNCT
dti-1334	528	1	the	the	DET
dti-1334	528	2	use	use	NOUN
dti-1334	528	3	of	of	ADP
dti-1334	528	4	molecular	molecular	ADJ
dti-1334	528	5	profi	profi	NOUN
dti-1334	528	6	ling	ling	PROPN
dti-1334	528	7	to	to	PART
dti-1334	528	8	predict	predict	VERB
dti-1334	528	9	survival	survival	NOUN
dti-1334	528	10	after	after	ADP
dti-1334	528	11	chemotherapy	chemotherapy	NOUN
dti-1334	528	12	for	for	ADP
dti-1334	528	13	diffuse	diffuse	ADJ
dti-1334	528	14	large	large	ADJ
dti-1334	528	15	-	-	PUNCT
dti-1334	528	16	b	b	NOUN
dti-1334	528	17	-	-	PUNCT
dti-1334	528	18	cell	cell	NOUN
dti-1334	528	19	lymphoma	lymphoma	NOUN
dti-1334	528	20	.	.	PUNCT
dti-1334	529	1	n.	n.	PROPN
dti-1334	529	2	engl	engl	PROPN
dti-1334	529	3	.	.	PUNCT
dti-1334	530	1	j.	j.	PROPN
dti-1334	530	2	med	med	PROPN
dti-1334	530	3	.	.	PROPN
dti-1334	530	4	,	,	PUNCT
dti-1334	530	5	346:1937–47	346:1937–47	X
dti-1334	530	6	.	.	PUNCT
dti-1334	530	7	rosenwald	rosenwald	NOUN
dti-1334	530	8	,	,	PUNCT
dti-1334	530	9	a.	a.	PROPN
dti-1334	530	10	,	,	PUNCT
dti-1334	530	11	wright	wright	PROPN
dti-1334	530	12	,	,	PUNCT
dti-1334	530	13	g.	g.	PROPN
dti-1334	530	14	,	,	PUNCT
dti-1334	530	15	wiestner	wiestner	NOUN
dti-1334	530	16	,	,	PUNCT
dti-1334	530	17	a.	a.	PROPN
dti-1334	530	18	,	,	PUNCT
dti-1334	530	19	chan	chan	PROPN
dti-1334	530	20	,	,	PUNCT
dti-1334	530	21	w.c	w.c	PROPN
dti-1334	530	22	.	.	PROPN
dti-1334	530	23	,	,	PUNCT
dti-1334	530	24	connors	connor	NOUN
dti-1334	530	25	,	,	PUNCT
dti-1334	530	26	j.m	j.m	PROPN
dti-1334	530	27	.	.	PROPN
dti-1334	530	28	,	,	PUNCT
dti-1334	530	29	campo	campo	PROPN
dti-1334	530	30	,	,	PUNCT
dti-1334	530	31	e.	e.	PROPN
dti-1334	530	32	,	,	PUNCT
dti-1334	530	33	gascoyne	gascoyne	PROPN
dti-1334	530	34	,	,	PUNCT
dti-1334	530	35	r.d	r.d	PROPN
dti-1334	530	36	.	.	PROPN
dti-1334	530	37	,	,	PUNCT
dti-1334	530	38	grogan	grogan	PROPN
dti-1334	530	39	,	,	PUNCT
dti-1334	530	40	t.m	t.m	PROPN
dti-1334	530	41	.	.	PROPN
dti-1334	530	42	,	,	PUNCT
dti-1334	530	43	muller	muller	NOUN
dti-1334	530	44	-	-	PUNCT
dti-1334	530	45	hermelink	hermelink	PROPN
dti-1334	530	46	,	,	PUNCT
dti-1334	530	47	h.k	h.k	PROPN
dti-1334	530	48	.	.	PROPN
dti-1334	530	49	,	,	PUNCT
dti-1334	530	50	smeland	smeland	NOUN
dti-1334	530	51	,	,	PUNCT
dti-1334	530	52	e.b	e.b	PROPN
dti-1334	530	53	.	.	PROPN
dti-1334	530	54	,	,	PUNCT
dti-1334	530	55	chiorazzi	chiorazzi	NOUN
dti-1334	530	56	,	,	PUNCT
dti-1334	530	57	m.	m.	NOUN
dti-1334	530	58	,	,	PUNCT
dti-1334	530	59	giltnane	giltnane	NOUN
dti-1334	530	60	,	,	PUNCT
dti-1334	530	61	j.m	j.m	PROPN
dti-1334	530	62	.	.	PROPN
dti-1334	530	63	,	,	PUNCT
dti-1334	530	64	hurt	hurt	VERB
dti-1334	530	65	,	,	PUNCT
dti-1334	530	66	e.m	e.m	PROPN
dti-1334	530	67	.	.	PROPN
dti-1334	530	68	,	,	PUNCT
dti-1334	530	69	zhao	zhao	PROPN
dti-1334	530	70	,	,	PUNCT
dti-1334	530	71	h.	h.	PROPN
dti-1334	530	72	,	,	PUNCT
dti-1334	530	73	averett	averett	PROPN
dti-1334	530	74	,	,	PUNCT
dti-1334	530	75	l.	l.	PROPN
dti-1334	530	76	,	,	PUNCT
dti-1334	530	77	henrickson	henrickson	PROPN
dti-1334	530	78	,	,	PUNCT
dti-1334	530	79	s.	s.	PROPN
dti-1334	530	80	,	,	PUNCT
dti-1334	530	81	yang	yang	PROPN
dti-1334	530	82	,	,	PUNCT
dti-1334	530	83	l.	l.	PROPN
dti-1334	530	84	,	,	PUNCT
dti-1334	530	85	powell	powell	PROPN
dti-1334	530	86	,	,	PUNCT
dti-1334	530	87	j.	j.	PROPN
dti-1334	530	88	,	,	PUNCT
dti-1334	530	89	wilson	wilson	PROPN
dti-1334	530	90	,	,	PUNCT
dti-1334	530	91	w.h	w.h	PROPN
dti-1334	530	92	.	.	PROPN
dti-1334	530	93	,	,	PUNCT
dti-1334	530	94	jaffe	jaffe	PROPN
dti-1334	530	95	,	,	PUNCT
dti-1334	530	96	e.s	e.s	PROPN
dti-1334	530	97	.	.	PROPN
dti-1334	530	98	,	,	PUNCT
dti-1334	530	99	simon	simon	PROPN
dti-1334	530	100	,	,	PUNCT
dti-1334	530	101	r.	r.	PROPN
dti-1334	530	102	,	,	PUNCT
dti-1334	530	103	klausner	klausner	PROPN
dti-1334	530	104	,	,	PUNCT
dti-1334	530	105	r.d	r.d	PROPN
dti-1334	530	106	.	.	PROPN
dti-1334	530	107	,	,	PUNCT
dti-1334	530	108	montserrat	montserrat	PROPN
dti-1334	530	109	,	,	PUNCT
dti-1334	530	110	e.	e.	PROPN
dti-1334	530	111	,	,	PUNCT
dti-1334	530	112	bosch	bosch	PROPN
dti-1334	530	113	,	,	PUNCT
dti-1334	530	114	f.	f.	PROPN
dti-1334	530	115	,	,	PUNCT
dti-1334	530	116	greiner	greiner	PROPN
dti-1334	530	117	,	,	PUNCT
dti-1334	530	118	t.c	t.c	PROPN
dti-1334	530	119	.	.	PROPN
dti-1334	530	120	,	,	PUNCT
dti-1334	530	121	weisenburger	weisenburger	NOUN
dti-1334	530	122	,	,	PUNCT
dti-1334	530	123	d.d	d.d	PROPN
dti-1334	530	124	.	.	PROPN
dti-1334	530	125	,	,	PUNCT
dti-1334	530	126	sanger	sanger	PROPN
dti-1334	530	127	,	,	PUNCT
dti-1334	530	128	w.g	w.g	PROPN
dti-1334	530	129	.	.	PROPN
dti-1334	530	130	,	,	PUNCT
dti-1334	530	131	dave	dave	PROPN
dti-1334	530	132	,	,	PUNCT
dti-1334	530	133	b.j	b.j	PROPN
dti-1334	530	134	.	.	PROPN
dti-1334	530	135	,	,	PUNCT
dti-1334	530	136	lynch	lynch	PROPN
dti-1334	530	137	,	,	PUNCT
dti-1334	530	138	j.c	j.c	PROPN
dti-1334	530	139	.	.	PROPN
dti-1334	530	140	,	,	PUNCT
dti-1334	530	141	vose	vose	PROPN
dti-1334	530	142	,	,	PUNCT
dti-1334	530	143	j.	j.	PROPN
dti-1334	530	144	,	,	PUNCT
dti-1334	530	145	armitage	armitage	PROPN
dti-1334	530	146	,	,	PUNCT
dti-1334	530	147	j.o	j.o	PROPN
dti-1334	530	148	.	.	PROPN
dti-1334	530	149	,	,	PUNCT
dti-1334	530	150	fisher	fisher	PROPN
dti-1334	530	151	,	,	PUNCT
dti-1334	530	152	r.i	r.i	PROPN
dti-1334	530	153	.	.	PROPN
dti-1334	530	154	,	,	PUNCT
dti-1334	530	155	miller	miller	PROPN
dti-1334	530	156	,	,	PUNCT
dti-1334	530	157	t.p	t.p	PROPN
dti-1334	530	158	.	.	PROPN
dti-1334	530	159	,	,	PUNCT
dti-1334	530	160	leblanc	leblanc	PROPN
dti-1334	530	161	,	,	PUNCT
dti-1334	530	162	m.	m.	NOUN
dti-1334	530	163	,	,	PUNCT
dti-1334	530	164	ott	ott	PROPN
dti-1334	530	165	,	,	PUNCT
dti-1334	530	166	g.	g.	PROPN
dti-1334	530	167	,	,	PUNCT
dti-1334	530	168	kvaloy	kvaloy	PROPN
dti-1334	530	169	,	,	PUNCT
dti-1334	530	170	s.	s.	PROPN
dti-1334	530	171	,	,	PUNCT
dti-1334	530	172	holte	holte	PROPN
dti-1334	530	173	,	,	PUNCT
dti-1334	530	174	h.	h.	PROPN
dti-1334	530	175	,	,	PUNCT
dti-1334	530	176	delabie	delabie	PROPN
dti-1334	530	177	,	,	PUNCT
dti-1334	530	178	j.	j.	PROPN
dti-1334	530	179	and	and	CCONJ
dti-1334	530	180	staudt	staudt	NOUN
dti-1334	530	181	,	,	PUNCT
dti-1334	530	182	l.m	l.m	PROPN
dti-1334	530	183	.	.	PROPN
dti-1334	530	184	2003	2003	NUM
dti-1334	530	185	.	.	PUNCT
dti-1334	531	1	the	the	DET
dti-1334	531	2	proliferation	proliferation	NOUN
dti-1334	531	3	gene	gene	NOUN
dti-1334	531	4	expression	expression	NOUN
dti-1334	531	5	signature	signature	NOUN
dti-1334	531	6	is	be	AUX
dti-1334	531	7	a	a	DET
dti-1334	531	8	quantitative	quantitative	ADJ
dti-1334	531	9	integrator	integrator	NOUN
dti-1334	531	10	of	of	ADP
dti-1334	531	11	oncogenic	oncogenic	ADJ
dti-1334	531	12	events	event	NOUN
dti-1334	531	13	that	that	PRON
dti-1334	531	14	predicts	predict	VERB
dti-1334	531	15	survival	survival	NOUN
dti-1334	531	16	in	in	ADP
dti-1334	531	17	mantle	mantle	ADJ
dti-1334	531	18	cell	cell	NOUN
dti-1334	531	19	lymphoma	lymphoma	NOUN
dti-1334	531	20	.	.	PUNCT
dti-1334	532	1	cancer	cancer	NOUN
dti-1334	532	2	cell	cell	NOUN
dti-1334	532	3	.	.	PUNCT
dti-1334	532	4	,	,	PUNCT
dti-1334	533	1	3:185–97	3:185–97	NUM
dti-1334	533	2	.	.	PUNCT
dti-1334	533	3	ross	ross	PROPN
dti-1334	533	4	,	,	PUNCT
dti-1334	533	5	p.l	p.l	PROPN
dti-1334	533	6	.	.	PROPN
dti-1334	533	7	,	,	PUNCT
dti-1334	533	8	huang	huang	PROPN
dti-1334	533	9	,	,	PUNCT
dti-1334	533	10	y.n	y.n	PROPN
dti-1334	533	11	.	.	PROPN
dti-1334	533	12	,	,	PUNCT
dti-1334	533	13	marchese	marchese	PROPN
dti-1334	533	14	,	,	PUNCT
dti-1334	533	15	j.n	j.n	PROPN
dti-1334	533	16	.	.	PROPN
dti-1334	533	17	,	,	PUNCT
dti-1334	533	18	williamson	williamson	PROPN
dti-1334	533	19	,	,	PUNCT
dti-1334	533	20	b.	b.	PROPN
dti-1334	533	21	,	,	PUNCT
dti-1334	533	22	parker	parker	PROPN
dti-1334	533	23	,	,	PUNCT
dti-1334	533	24	k.	k.	PROPN
dti-1334	533	25	,	,	PUNCT
dti-1334	533	26	hattan	hattan	PROPN
dti-1334	533	27	,	,	PUNCT
dti-1334	533	28	s.	s.	PROPN
dti-1334	533	29	,	,	PUNCT
dti-1334	533	30	khainovski	khainovski	PROPN
dti-1334	533	31	,	,	PUNCT
dti-1334	533	32	n.	n.	NOUN
dti-1334	533	33	,	,	PUNCT
dti-1334	533	34	pillai	pillai	PROPN
dti-1334	533	35	,	,	PUNCT
dti-1334	533	36	s.	s.	PROPN
dti-1334	533	37	,	,	PUNCT
dti-1334	533	38	dey	dey	PROPN
dti-1334	533	39	,	,	PUNCT
dti-1334	533	40	s.	s.	PROPN
dti-1334	533	41	,	,	PUNCT
dti-1334	533	42	daniels	daniels	PROPN
dti-1334	533	43	,	,	PUNCT
dti-1334	533	44	s.	s.	PROPN
dti-1334	533	45	,	,	PUNCT
dti-1334	533	46	purkayastha	purkayastha	NOUN
dti-1334	533	47	,	,	PUNCT
dti-1334	533	48	s.	s.	PROPN
dti-1334	533	49	,	,	PUNCT
dti-1334	533	50	juhasz	juhasz	PROPN
dti-1334	533	51	,	,	PUNCT
dti-1334	533	52	p.	p.	PROPN
dti-1334	533	53	,	,	PUNCT
dti-1334	533	54	martin	martin	PROPN
dti-1334	533	55	,	,	PUNCT
dti-1334	533	56	s.	s.	PROPN
dti-1334	533	57	,	,	PUNCT
dti-1334	533	58	bartlet	bartlet	PROPN
dti-1334	533	59	-	-	PUNCT
dti-1334	533	60	jones	jones	PROPN
dti-1334	533	61	,	,	PUNCT
dti-1334	533	62	m.	m.	NOUN
dti-1334	533	63	,	,	PUNCT
dti-1334	533	64	he	he	PRON
dti-1334	533	65	,	,	PUNCT
dti-1334	533	66	f.	f.	PROPN
dti-1334	533	67	,	,	PUNCT
dti-1334	533	68	jacobson	jacobson	PROPN
dti-1334	533	69	,	,	PUNCT
dti-1334	533	70	a.	a.	NOUN
dti-1334	533	71	and	and	CCONJ
dti-1334	533	72	pappin	pappin	PROPN
dti-1334	533	73	,	,	PUNCT
dti-1334	533	74	d.j	d.j	PROPN
dti-1334	533	75	.	.	PROPN
dti-1334	533	76	2004	2004	NUM
dti-1334	533	77	.	.	PUNCT
dti-1334	534	1	multiplexed	multiplexed	ADJ
dti-1334	534	2	protein	protein	NOUN
dti-1334	534	3	quantitation	quantitation	NOUN
dti-1334	534	4	in	in	ADP
dti-1334	534	5	saccharomyces	saccharomyce	NOUN
dti-1334	534	6	cerevisiae	cerevisiae	NOUN
dti-1334	534	7	using	use	VERB
dti-1334	534	8	amine	amine	ADJ
dti-1334	534	9	-	-	PUNCT
dti-1334	534	10	reactive	reactive	ADJ
dti-1334	534	11	isobaric	isobaric	ADJ
dti-1334	534	12	tagging	tagging	NOUN
dti-1334	534	13	reagents	reagent	NOUN
dti-1334	534	14	.	.	PUNCT
dti-1334	535	1	mol	mol	NOUN
dti-1334	535	2	.	.	PUNCT
dti-1334	535	3	cell	cell	NOUN
dti-1334	535	4	.	.	PUNCT
dti-1334	536	1	proteomics	proteomic	NOUN
dti-1334	536	2	,	,	PUNCT
dti-1334	536	3	3:1154–69	3:1154–69	NUM
dti-1334	536	4	.	.	PUNCT
dti-1334	537	1	ruths	ruth	NOUN
dti-1334	537	2	,	,	PUNCT
dti-1334	537	3	d.a	d.a	PROPN
dti-1334	537	4	.	.	PROPN
dti-1334	537	5	,	,	PUNCT
dti-1334	537	6	chen	chen	PROPN
dti-1334	537	7	,	,	PUNCT
dti-1334	537	8	e.s	e.s	PROPN
dti-1334	537	9	.	.	PROPN
dti-1334	537	10	and	and	CCONJ
dti-1334	537	11	ellis	ellis	PROPN
dti-1334	537	12	,	,	PUNCT
dti-1334	537	13	l.	l.	PROPN
dti-1334	537	14	2000	2000	NUM
dti-1334	537	15	.	.	PUNCT
dti-1334	538	1	arbor	arbor	PROPN
dti-1334	538	2	3d	3d	NOUN
dti-1334	538	3	:	:	PUNCT
dti-1334	538	4	an	an	DET
dti-1334	538	5	interactive	interactive	ADJ
dti-1334	538	6	environment	environment	NOUN
dti-1334	538	7	for	for	ADP
dti-1334	538	8	examining	examine	VERB
dti-1334	538	9	phylogenetic	phylogenetic	ADJ
dti-1334	538	10	and	and	CCONJ
dti-1334	538	11	taxonomic	taxonomic	ADJ
dti-1334	538	12	trees	tree	NOUN
dti-1334	538	13	in	in	ADP
dti-1334	538	14	multiple	multiple	ADJ
dti-1334	538	15	dimensions	dimension	NOUN
dti-1334	538	16	.	.	PUNCT
dti-1334	539	1	bioinformatics	bioinformatic	NOUN
dti-1334	539	2	,	,	PUNCT
dti-1334	539	3	16:1003–9	16:1003–9	NUM
dti-1334	539	4	.	.	PUNCT
dti-1334	540	1	salamonsen	salamonsen	PROPN
dti-1334	540	2	,	,	PUNCT
dti-1334	540	3	w.	w.	PROPN
dti-1334	540	4	,	,	PUNCT
dti-1334	540	5	mok	mok	PROPN
dti-1334	540	6	,	,	PUNCT
dti-1334	540	7	k.y	k.y	PROPN
dti-1334	540	8	.	.	PROPN
dti-1334	540	9	,	,	PUNCT
dti-1334	540	10	kolatkar	kolatkar	PROPN
dti-1334	540	11	,	,	PUNCT
dti-1334	540	12	p.	p.	NOUN
dti-1334	540	13	and	and	CCONJ
dti-1334	540	14	subbiah	subbiah	PROPN
dti-1334	540	15	,	,	PUNCT
dti-1334	540	16	s.	s.	PROPN
dti-1334	540	17	1999	1999	NUM
dti-1334	540	18	.	.	PUNCT
dti-1334	541	1	biojake	biojake	NOUN
dti-1334	541	2	:	:	PUNCT
dti-1334	541	3	a	a	DET
dti-1334	541	4	tool	tool	NOUN
dti-1334	541	5	for	for	ADP
dti-1334	541	6	the	the	DET
dti-1334	541	7	creation	creation	NOUN
dti-1334	541	8	,	,	PUNCT
dti-1334	541	9	visualization	visualization	NOUN
dti-1334	541	10	and	and	CCONJ
dti-1334	541	11	manipulation	manipulation	NOUN
dti-1334	541	12	of	of	ADP
dti-1334	541	13	metabolic	metabolic	NOUN
dti-1334	541	14	pathways	pathway	NOUN
dti-1334	541	15	.	.	PUNCT
dti-1334	542	1	pac	pac	PROPN
dti-1334	542	2	.	.	PROPN
dti-1334	542	3	symp	symp	PROPN
dti-1334	542	4	.	.	PUNCT
dti-1334	543	1	biocomput	biocomput	NOUN
dti-1334	543	2	.	.	PUNCT
dti-1334	543	3	,	,	PUNCT
dti-1334	544	1	392–400	392–400	NUM
dti-1334	544	2	.	.	PUNCT
dti-1334	545	1	senzer	senzer	NOUN
dti-1334	545	2	,	,	PUNCT
dti-1334	545	3	n.	n.	PROPN
dti-1334	545	4	,	,	PUNCT
dti-1334	545	5	shen	shen	PROPN
dti-1334	545	6	,	,	PUNCT
dti-1334	545	7	y.	y.	PROPN
dti-1334	545	8	,	,	PUNCT
dti-1334	545	9	hill	hill	PROPN
dti-1334	545	10	,	,	PUNCT
dti-1334	545	11	c.	c.	PROPN
dti-1334	545	12	and	and	CCONJ
dti-1334	545	13	nemunaitis	nemunaitis	PROPN
dti-1334	545	14	,	,	PUNCT
dti-1334	545	15	j.	j.	PROPN
dti-1334	545	16	2005	2005	NUM
dti-1334	545	17	.	.	PUNCT
dti-1334	546	1	individualised	individualised	ADJ
dti-1334	546	2	cancer	cancer	NOUN
dti-1334	546	3	therapeutics	therapeutic	NOUN
dti-1334	546	4	:	:	PUNCT
dti-1334	546	5	dream	dream	NOUN
dti-1334	546	6	or	or	CCONJ
dti-1334	546	7	reality	reality	NOUN
dti-1334	546	8	?	?	PUNCT
dti-1334	547	1	expert	expert	NOUN
dti-1334	547	2	opin	opin	NOUN
dti-1334	547	3	.	.	PUNCT
dti-1334	548	1	ther	ther	PROPN
dti-1334	548	2	.	.	PUNCT
dti-1334	549	1	targets	target	NOUN
dti-1334	549	2	,	,	PUNCT
dti-1334	549	3	9:1189–201	9:1189–201	NOUN
dti-1334	549	4	.	.	PUNCT
dti-1334	550	1	shaw	shaw	PROPN
dti-1334	550	2	,	,	PUNCT
dti-1334	550	3	j.	j.	PROPN
dti-1334	550	4	,	,	PUNCT
dti-1334	550	5	rowlinson	rowlinson	PROPN
dti-1334	550	6	,	,	PUNCT
dti-1334	550	7	r.	r.	PROPN
dti-1334	550	8	,	,	PUNCT
dti-1334	550	9	nickson	nickson	PROPN
dti-1334	550	10	,	,	PUNCT
dti-1334	550	11	j.	j.	PROPN
dti-1334	550	12	,	,	PUNCT
dti-1334	550	13	stone	stone	NOUN
dti-1334	550	14	,	,	PUNCT
dti-1334	550	15	t.	t.	NOUN
dti-1334	550	16	,	,	PUNCT
dti-1334	550	17	sweet	sweet	ADJ
dti-1334	550	18	,	,	PUNCT
dti-1334	550	19	a.	a.	NOUN
dti-1334	550	20	,	,	PUNCT
dti-1334	550	21	williams	williams	PROPN
dti-1334	550	22	,	,	PUNCT
dti-1334	550	23	k.	k.	PROPN
dti-1334	550	24	and	and	CCONJ
dti-1334	550	25	tonge	tonge	PROPN
dti-1334	550	26	,	,	PUNCT
dti-1334	550	27	r.	r.	PROPN
dti-1334	550	28	2003	2003	NUM
dti-1334	550	29	.	.	PUNCT
dti-1334	551	1	evaluation	evaluation	NOUN
dti-1334	551	2	of	of	ADP
dti-1334	551	3	saturation	saturation	NOUN
dti-1334	551	4	labelling	label	VERB
dti-1334	551	5	two	two	NUM
dti-1334	551	6	-	-	PUNCT
dti-1334	551	7	dimensional	dimensional	ADJ
dti-1334	551	8	difference	difference	NOUN
dti-1334	551	9	gel	gel	NOUN
dti-1334	551	10	electrophoresis	electrophoresis	NOUN
dti-1334	551	11	fl	fl	NUM
dti-1334	551	12	uorescent	uorescent	ADJ
dti-1334	551	13	dyes	dye	NOUN
dti-1334	551	14	.	.	PUNCT
dti-1334	552	1	proteomics	proteomic	NOUN
dti-1334	552	2	,	,	PUNCT
dti-1334	552	3	3:1181–95	3:1181–95	NUM
dti-1334	552	4	.	.	PUNCT
dti-1334	553	1	shiio	shiio	NOUN
dti-1334	553	2	,	,	PUNCT
dti-1334	553	3	y.	y.	PROPN
dti-1334	553	4	and	and	CCONJ
dti-1334	553	5	aebersold	aebersold	PROPN
dti-1334	553	6	,	,	PUNCT
dti-1334	553	7	r.	r.	PROPN
dti-1334	553	8	2006	2006	NUM
dti-1334	553	9	.	.	PUNCT
dti-1334	554	1	quantitative	quantitative	ADJ
dti-1334	554	2	proteome	proteome	ADJ
dti-1334	554	3	analysis	analysis	NOUN
dti-1334	554	4	using	use	VERB
dti-1334	554	5	isotope	isotope	NOUN
dti-1334	554	6	-	-	PUNCT
dti-1334	554	7	coded	code	VERB
dti-1334	554	8	affi	affi	ADJ
dti-1334	554	9	nity	nity	NOUN
dti-1334	554	10	tags	tag	NOUN
dti-1334	554	11	and	and	CCONJ
dti-1334	554	12	mass	mass	ADJ
dti-1334	554	13	spectrometry	spectrometry	NOUN
dti-1334	554	14	.	.	PUNCT
dti-1334	555	1	nat	nat	PROPN
dti-1334	555	2	.	.	PUNCT
dti-1334	556	1	protoc	protoc	VERB
dti-1334	556	2	.	.	PUNCT
dti-1334	556	3	,	,	PUNCT
dti-1334	557	1	1:139–45	1:139–45	NUM
dti-1334	557	2	.	.	PUNCT
dti-1334	557	3	shipp	shipp	NOUN
dti-1334	557	4	,	,	PUNCT
dti-1334	557	5	m.a	m.a	PROPN
dti-1334	557	6	.	.	PROPN
dti-1334	557	7	,	,	PUNCT
dti-1334	557	8	ross	ross	PROPN
dti-1334	557	9	,	,	PUNCT
dti-1334	557	10	k.n	k.n	PROPN
dti-1334	557	11	.	.	PROPN
dti-1334	557	12	,	,	PUNCT
dti-1334	557	13	tamayo	tamayo	PROPN
dti-1334	557	14	,	,	PUNCT
dti-1334	557	15	p.	p.	PROPN
dti-1334	557	16	,	,	PUNCT
dti-1334	557	17	weng	weng	PROPN
dti-1334	557	18	,	,	PUNCT
dti-1334	557	19	a.p	a.p	PROPN
dti-1334	557	20	.	.	PROPN
dti-1334	557	21	,	,	PUNCT
dti-1334	557	22	kutok	kutok	PROPN
dti-1334	557	23	,	,	PUNCT
dti-1334	557	24	j.l	j.l	PROPN
dti-1334	557	25	.	.	PROPN
dti-1334	557	26	,	,	PUNCT
dti-1334	557	27	aguiar	aguiar	PROPN
dti-1334	557	28	,	,	PUNCT
dti-1334	557	29	r.c	r.c	PROPN
dti-1334	557	30	.	.	PROPN
dti-1334	557	31	,	,	PUNCT
dti-1334	557	32	gaasenbeek	gaasenbeek	ADJ
dti-1334	557	33	,	,	PUNCT
dti-1334	557	34	m.	m.	NOUN
dti-1334	557	35	,	,	PUNCT
dti-1334	557	36	angelo	angelo	PROPN
dti-1334	557	37	,	,	PUNCT
dti-1334	557	38	m.	m.	NOUN
dti-1334	557	39	,	,	PUNCT
dti-1334	557	40	reich	reich	PROPN
dti-1334	557	41	,	,	PUNCT
dti-1334	557	42	m.	m.	NOUN
dti-1334	557	43	,	,	PUNCT
dti-1334	557	44	pinkus	pinku	NOUN
dti-1334	557	45	,	,	PUNCT
dti-1334	557	46	g.s	g.s	PROPN
dti-1334	557	47	.	.	PROPN
dti-1334	557	48	,	,	PUNCT
dti-1334	557	49	ray	ray	PROPN
dti-1334	557	50	,	,	PUNCT
dti-1334	557	51	t.s	t.s	PROPN
dti-1334	557	52	.	.	PROPN
dti-1334	557	53	,	,	PUNCT
dti-1334	557	54	koval	koval	PROPN
dti-1334	557	55	,	,	PUNCT
dti-1334	557	56	m.a	m.a	PROPN
dti-1334	557	57	.	.	PROPN
dti-1334	557	58	,	,	PUNCT
dti-1334	557	59	last	last	ADJ
dti-1334	557	60	,	,	PUNCT
dti-1334	557	61	k.w	k.w	PROPN
dti-1334	557	62	.	.	PROPN
dti-1334	557	63	,	,	PUNCT
dti-1334	557	64	norton	norton	PROPN
dti-1334	557	65	,	,	PUNCT
dti-1334	557	66	a.	a.	PROPN
dti-1334	557	67	,	,	PUNCT
dti-1334	557	68	lister	lister	PROPN
dti-1334	557	69	,	,	PUNCT
dti-1334	557	70	t.a	t.a	PROPN
dti-1334	557	71	.	.	PROPN
dti-1334	557	72	,	,	PUNCT
dti-1334	557	73	mesirov	mesirov	PROPN
dti-1334	557	74	,	,	PUNCT
dti-1334	557	75	j.	j.	PROPN
dti-1334	557	76	,	,	PUNCT
dti-1334	557	77	neuberg	neuberg	PROPN
dti-1334	557	78	,	,	PUNCT
dti-1334	557	79	d.s	d.s	PROPN
dti-1334	557	80	.	.	PROPN
dti-1334	557	81	,	,	PUNCT
dti-1334	557	82	lander	lander	PROPN
dti-1334	557	83	,	,	PUNCT
dti-1334	557	84	e.s	e.s	PROPN
dti-1334	557	85	.	.	PROPN
dti-1334	557	86	,	,	PUNCT
dti-1334	557	87	aster	aster	NOUN
dti-1334	557	88	,	,	PUNCT
dti-1334	557	89	j.c	j.c	PROPN
dti-1334	557	90	.	.	PROPN
dti-1334	557	91	and	and	CCONJ
dti-1334	557	92	golub	golub	PROPN
dti-1334	557	93	,	,	PUNCT
dti-1334	557	94	t.r	t.r	PROPN
dti-1334	557	95	.	.	PROPN
dti-1334	557	96	2002	2002	NUM
dti-1334	557	97	.	.	PUNCT
dti-1334	558	1	diffuse	diffuse	VERB
dti-1334	558	2	large	large	ADJ
dti-1334	558	3	b	b	NUM
dti-1334	558	4	-	-	PUNCT
dti-1334	558	5	cell	cell	NOUN
dti-1334	558	6	lymphoma	lymphoma	NOUN
dti-1334	558	7	outcome	outcome	NOUN
dti-1334	558	8	prediction	prediction	NOUN
dti-1334	558	9	by	by	ADP
dti-1334	558	10	gene	gene	NOUN
dti-1334	558	11	-	-	PUNCT
dti-1334	558	12	expression	expression	NOUN
dti-1334	558	13	profi	profi	NOUN
dti-1334	558	14	ling	ling	PROPN
dti-1334	558	15	and	and	CCONJ
dti-1334	558	16	supervised	supervise	VERB
dti-1334	558	17	machine	machine	NOUN
dti-1334	558	18	learning	learning	NOUN
dti-1334	558	19	.	.	PUNCT
dti-1334	559	1	nat	nat	PROPN
dti-1334	559	2	.	.	PUNCT
dti-1334	560	1	med	med	PROPN
dti-1334	560	2	.	.	PROPN
dti-1334	560	3	,	,	PUNCT
dti-1334	560	4	8:68–74	8:68–74	NUM
dti-1334	560	5	.	.	PUNCT
dti-1334	561	1	simone	simone	PROPN
dti-1334	561	2	,	,	PUNCT
dti-1334	561	3	n.l	n.l	PROPN
dti-1334	561	4	.	.	PROPN
dti-1334	561	5	,	,	PUNCT
dti-1334	561	6	bonner	bonner	PROPN
dti-1334	561	7	,	,	PUNCT
dti-1334	561	8	r.f	r.f	PROPN
dti-1334	561	9	.	.	PROPN
dti-1334	561	10	,	,	PUNCT
dti-1334	561	11	gillespie	gillespie	PROPN
dti-1334	561	12	,	,	PUNCT
dti-1334	561	13	j.w	j.w	PROPN
dti-1334	561	14	.	.	PROPN
dti-1334	561	15	,	,	PUNCT
dti-1334	561	16	emmert	emmert	NOUN
dti-1334	561	17	-	-	PUNCT
dti-1334	561	18	buck	buck	NOUN
dti-1334	561	19	,	,	PUNCT
dti-1334	561	20	m.r	m.r	PROPN
dti-1334	561	21	.	.	PROPN
dti-1334	561	22	and	and	CCONJ
dti-1334	561	23	liotta	liotta	PROPN
dti-1334	561	24	,	,	PUNCT
dti-1334	561	25	l.a	l.a	PROPN
dti-1334	561	26	.	.	PROPN
dti-1334	561	27	1998	1998	NUM
dti-1334	561	28	.	.	PUNCT
dti-1334	562	1	laser	laser	NOUN
dti-1334	562	2	-	-	PUNCT
dti-1334	562	3	capture	capture	NOUN
dti-1334	562	4	microdissection	microdissection	NOUN
dti-1334	562	5	:	:	PUNCT
dti-1334	562	6	opening	open	VERB
dti-1334	562	7	the	the	DET
dti-1334	562	8	microscopic	microscopic	ADJ
dti-1334	562	9	frontier	frontier	NOUN
dti-1334	562	10	to	to	ADP
dti-1334	562	11	molecular	molecular	ADJ
dti-1334	562	12	analysis	analysis	NOUN
dti-1334	562	13	.	.	PUNCT
dti-1334	563	1	trends	trend	NOUN
dti-1334	563	2	genet	genet	PROPN
dti-1334	563	3	.	.	PUNCT
dti-1334	563	4	,	,	PUNCT
dti-1334	563	5	14:272–6	14:272–6	NUM
dti-1334	563	6	.	.	PUNCT
dti-1334	563	7	siolas	siolas	PROPN
dti-1334	563	8	,	,	PUNCT
dti-1334	563	9	d.	d.	PROPN
dti-1334	563	10	,	,	PUNCT
dti-1334	563	11	lerner	lerner	PROPN
dti-1334	563	12	,	,	PUNCT
dti-1334	563	13	c.	c.	PROPN
dti-1334	563	14	,	,	PUNCT
dti-1334	563	15	burchard	burchard	PROPN
dti-1334	563	16	,	,	PUNCT
dti-1334	563	17	j.	j.	PROPN
dti-1334	563	18	,	,	PUNCT
dti-1334	563	19	ge	ge	PROPN
dti-1334	563	20	,	,	PUNCT
dti-1334	563	21	w.	w.	PROPN
dti-1334	563	22	,	,	PUNCT
dti-1334	563	23	linsley	linsley	PROPN
dti-1334	563	24	,	,	PUNCT
dti-1334	563	25	p.s	p.s	PROPN
dti-1334	563	26	.	.	PROPN
dti-1334	563	27	,	,	PUNCT
dti-1334	563	28	paddison	paddison	PROPN
dti-1334	563	29	,	,	PUNCT
dti-1334	563	30	p.j	p.j	PROPN
dti-1334	563	31	.	.	PROPN
dti-1334	563	32	,	,	PUNCT
dti-1334	563	33	hannon	hannon	PROPN
dti-1334	563	34	,	,	PUNCT
dti-1334	563	35	g.j	g.j	PROPN
dti-1334	563	36	.	.	PROPN
dti-1334	563	37	and	and	CCONJ
dti-1334	563	38	cleary	cleary	PROPN
dti-1334	563	39	,	,	PUNCT
dti-1334	563	40	m.a	m.a	PROPN
dti-1334	563	41	.	.	PROPN
dti-1334	563	42	2005	2005	NUM
dti-1334	563	43	.	.	PUNCT
dti-1334	564	1	synthetic	synthetic	NOUN
dti-1334	564	2	shrnas	shrna	NOUN
dti-1334	564	3	as	as	ADP
dti-1334	564	4	potent	potent	ADJ
dti-1334	564	5	rnai	rnai	PROPN
dti-1334	564	6	triggers	trigger	NOUN
dti-1334	564	7	.	.	PUNCT
dti-1334	565	1	nat	nat	NOUN
dti-1334	565	2	.	.	PUNCT
dti-1334	566	1	biotechnol	biotechnol	PROPN
dti-1334	566	2	.	.	PUNCT
dti-1334	566	3	,	,	PUNCT
dti-1334	566	4	23:227–31	23:227–31	PROPN
dti-1334	566	5	.	.	PUNCT
dti-1334	566	6	sirava	sirava	NOUN
dti-1334	566	7	,	,	PUNCT
dti-1334	566	8	m.	m.	NOUN
dti-1334	566	9	,	,	PUNCT
dti-1334	566	10	schafer	schafer	PROPN
dti-1334	566	11	,	,	PUNCT
dti-1334	566	12	t.	t.	PROPN
dti-1334	566	13	,	,	PUNCT
dti-1334	566	14	eiglsperger	eiglsperger	ADV
dti-1334	566	15	,	,	PUNCT
dti-1334	566	16	m.	m.	NOUN
dti-1334	566	17	,	,	PUNCT
dti-1334	566	18	kaufmann	kaufmann	PROPN
dti-1334	566	19	,	,	PUNCT
dti-1334	566	20	m.	m.	NOUN
dti-1334	566	21	,	,	PUNCT
dti-1334	566	22	kohlbacher	kohlbacher	NOUN
dti-1334	566	23	,	,	PUNCT
dti-1334	566	24	o.	o.	PROPN
dti-1334	566	25	,	,	PUNCT
dti-1334	566	26	bornberg	bornberg	PROPN
dti-1334	566	27	-	-	PUNCT
dti-1334	566	28	bauer	bauer	PROPN
dti-1334	566	29	,	,	PUNCT
dti-1334	566	30	e.	e.	PROPN
dti-1334	566	31	and	and	CCONJ
dti-1334	566	32	lenhof	lenhof	NOUN
dti-1334	566	33	,	,	PUNCT
dti-1334	566	34	h.p	h.p	PROPN
dti-1334	566	35	.	.	PROPN
dti-1334	566	36	2002	2002	NUM
dti-1334	566	37	.	.	PUNCT
dti-1334	567	1	biominer	biominer	NOUN
dti-1334	567	2	—	—	PUNCT
dti-1334	567	3	modeling	modeling	NOUN
dti-1334	567	4	,	,	PUNCT
dti-1334	567	5	analyzing	analyzing	NOUN
dti-1334	567	6	,	,	PUNCT
dti-1334	567	7	and	and	CCONJ
dti-1334	567	8	visualizing	visualize	VERB
dti-1334	567	9	biochemical	biochemical	ADJ
dti-1334	567	10	pathways	pathway	NOUN
dti-1334	567	11	and	and	CCONJ
dti-1334	567	12	networks	network	NOUN
dti-1334	567	13	.	.	PUNCT
dti-1334	568	1	bioinformatics	bioinformatic	NOUN
dti-1334	568	2	,	,	PUNCT
dti-1334	568	3	18(suppl	18(suppl	NUM
dti-1334	568	4	2):s219–30	2):s219–30	NUM
dti-1334	568	5	.	.	PUNCT
dti-1334	568	6	sitek	sitek	PROPN
dti-1334	568	7	,	,	PUNCT
dti-1334	568	8	b.	b.	PROPN
dti-1334	568	9	,	,	PUNCT
dti-1334	568	10	potthoff	potthoff	PROPN
dti-1334	568	11	,	,	PUNCT
dti-1334	568	12	s.	s.	PROPN
dti-1334	568	13	,	,	PUNCT
dti-1334	568	14	schulenborg	schulenborg	ADJ
dti-1334	568	15	,	,	PUNCT
dti-1334	568	16	t.	t.	PROPN
dti-1334	568	17	,	,	PUNCT
dti-1334	568	18	stegbauer	stegbauer	PROPN
dti-1334	568	19	,	,	PUNCT
dti-1334	568	20	j.	j.	PROPN
dti-1334	568	21	,	,	PUNCT
dti-1334	568	22	vinke	vinke	ADJ
dti-1334	568	23	,	,	PUNCT
dti-1334	568	24	t.	t.	NOUN
dti-1334	568	25	,	,	PUNCT
dti-1334	568	26	rump	rump	NOUN
dti-1334	568	27	,	,	PUNCT
dti-1334	568	28	l.c	l.c	PROPN
dti-1334	568	29	.	.	PROPN
dti-1334	568	30	,	,	PUNCT
dti-1334	568	31	meyer	meyer	PROPN
dti-1334	568	32	,	,	PUNCT
dti-1334	568	33	h.e	h.e	PROPN
dti-1334	568	34	.	.	PROPN
dti-1334	568	35	,	,	PUNCT
dti-1334	568	36	vonend	vonend	NOUN
dti-1334	568	37	,	,	PUNCT
dti-1334	568	38	o.	o.	NOUN
dti-1334	568	39	and	and	CCONJ
dti-1334	568	40	stuhler	stuhler	NOUN
dti-1334	568	41	,	,	PUNCT
dti-1334	568	42	k.	k.	PROPN
dti-1334	568	43	2006	2006	NUM
dti-1334	568	44	.	.	PUNCT
dti-1334	569	1	novel	novel	ADJ
dti-1334	569	2	approaches	approach	NOUN
dti-1334	569	3	to	to	PART
dti-1334	569	4	analyse	analyse	VERB
dti-1334	569	5	glomerular	glomerular	ADJ
dti-1334	569	6	proteins	protein	NOUN
dti-1334	569	7	from	from	ADP
dti-1334	569	8	smallest	small	ADJ
dti-1334	569	9	scale	scale	NOUN
dti-1334	569	10	murine	murine	ADJ
dti-1334	569	11	and	and	CCONJ
dti-1334	569	12	human	human	ADJ
dti-1334	569	13	samples	sample	NOUN
dti-1334	569	14	using	use	VERB
dti-1334	569	15	dige	dige	NOUN
dti-1334	569	16	saturation	saturation	NOUN
dti-1334	569	17	labelling	labelling	NOUN
dti-1334	569	18	.	.	PUNCT
dti-1334	570	1	proteomics	proteomic	NOUN
dti-1334	570	2	,	,	PUNCT
dti-1334	570	3	6:4337–45	6:4337–45	NOUN
dti-1334	570	4	.	.	PUNCT
dti-1334	571	1	smolka	smolka	PROPN
dti-1334	571	2	,	,	PUNCT
dti-1334	571	3	m.b	m.b	PROPN
dti-1334	571	4	.	.	PROPN
dti-1334	571	5	,	,	PUNCT
dti-1334	571	6	zhou	zhou	PROPN
dti-1334	571	7	,	,	PUNCT
dti-1334	571	8	h.	h.	PROPN
dti-1334	571	9	,	,	PUNCT
dti-1334	571	10	purkayastha	purkayastha	NOUN
dti-1334	571	11	,	,	PUNCT
dti-1334	571	12	s.	s.	PROPN
dti-1334	571	13	and	and	CCONJ
dti-1334	571	14	aebersold	aebersold	PROPN
dti-1334	571	15	,	,	PUNCT
dti-1334	571	16	r.	r.	PROPN
dti-1334	571	17	2001	2001	NUM
dti-1334	571	18	.	.	PUNCT
dti-1334	572	1	optimization	optimization	NOUN
dti-1334	572	2	of	of	ADP
dti-1334	572	3	the	the	DET
dti-1334	572	4	isotope	isotope	NOUN
dti-1334	572	5	-	-	PUNCT
dti-1334	572	6	coded	code	VERB
dti-1334	572	7	affi	affi	PROPN
dti-1334	572	8	nity	nity	NOUN
dti-1334	572	9	tag	tag	NOUN
dti-1334	572	10	-	-	PUNCT
dti-1334	572	11	labeling	labeling	NOUN
dti-1334	572	12	procedure	procedure	NOUN
dti-1334	572	13	for	for	ADP
dti-1334	572	14	quantitative	quantitative	ADJ
dti-1334	572	15	proteome	proteome	ADJ
dti-1334	572	16	analysis	analysis	NOUN
dti-1334	572	17	.	.	PUNCT
dti-1334	573	1	anal	anal	PROPN
dti-1334	573	2	.	.	PUNCT
dti-1334	573	3	biochem	biochem	PROPN
dti-1334	573	4	.	.	PUNCT
dti-1334	573	5	,	,	PUNCT
dti-1334	574	1	297:25–31	297:25–31	X
dti-1334	574	2	.	.	PUNCT
dti-1334	574	3	somiari	somiari	PROPN
dti-1334	574	4	,	,	PUNCT
dti-1334	574	5	r.i	r.i	PROPN
dti-1334	574	6	.	.	PROPN
dti-1334	574	7	,	,	PUNCT
dti-1334	574	8	somiari	somiari	PROPN
dti-1334	574	9	,	,	PUNCT
dti-1334	574	10	s.	s.	PROPN
dti-1334	574	11	,	,	PUNCT
dti-1334	574	12	russell	russell	PROPN
dti-1334	574	13	,	,	PUNCT
dti-1334	574	14	s.	s.	PROPN
dti-1334	574	15	and	and	CCONJ
dti-1334	574	16	shriver	shriver	PROPN
dti-1334	574	17	,	,	PUNCT
dti-1334	574	18	c.d	c.d	PROPN
dti-1334	574	19	.	.	PROPN
dti-1334	574	20	2005	2005	NUM
dti-1334	574	21	.	.	PUNCT
dti-1334	575	1	proteomics	proteomic	NOUN
dti-1334	575	2	of	of	ADP
dti-1334	575	3	breast	breast	NOUN
dti-1334	575	4	carcinoma	carcinoma	NOUN
dti-1334	575	5	.	.	PUNCT
dti-1334	576	1	j.	j.	PROPN
dti-1334	576	2	chromatogr	chromatogr	PROPN
dti-1334	576	3	b.	b.	PROPN
dti-1334	576	4	analyt	analyt	PROPN
dti-1334	576	5	technol	technol	PROPN
dti-1334	576	6	biomed	biome	VERB
dti-1334	576	7	life	life	NOUN
dti-1334	576	8	sci	sci	PROPN
dti-1334	576	9	.	.	PROPN
dti-1334	576	10	,	,	PUNCT
dti-1334	576	11	815:215–25	815:215–25	NUM
dti-1334	576	12	.	.	PUNCT
dti-1334	577	1	somiari	somiari	PROPN
dti-1334	577	2	,	,	PUNCT
dti-1334	577	3	r.i	r.i	PROPN
dti-1334	577	4	.	.	PROPN
dti-1334	577	5	,	,	PUNCT
dti-1334	577	6	sullivan	sullivan	PROPN
dti-1334	577	7	,	,	PUNCT
dti-1334	577	8	a.	a.	PROPN
dti-1334	577	9	,	,	PUNCT
dti-1334	577	10	russell	russell	PROPN
dti-1334	577	11	,	,	PUNCT
dti-1334	577	12	s.	s.	PROPN
dti-1334	577	13	,	,	PUNCT
dti-1334	577	14	somiari	somiari	PROPN
dti-1334	577	15	,	,	PUNCT
dti-1334	577	16	s.	s.	PROPN
dti-1334	577	17	,	,	PUNCT
dti-1334	577	18	hu	hu	PROPN
dti-1334	577	19	,	,	PUNCT
dti-1334	577	20	h.	h.	PROPN
dti-1334	577	21	,	,	PUNCT
dti-1334	577	22	jordan	jordan	PROPN
dti-1334	577	23	,	,	PUNCT
dti-1334	577	24	r.	r.	PROPN
dti-1334	577	25	,	,	PUNCT
dti-1334	577	26	george	george	PROPN
dti-1334	577	27	,	,	PUNCT
dti-1334	577	28	a.	a.	PROPN
dti-1334	577	29	,	,	PUNCT
dti-1334	577	30	katenhusen	katenhusen	PROPN
dti-1334	577	31	,	,	PUNCT
dti-1334	577	32	r.	r.	PROPN
dti-1334	577	33	,	,	PUNCT
dti-1334	577	34	buchowiecka	buchowiecka	PROPN
dti-1334	577	35	,	,	PUNCT
dti-1334	577	36	a.	a.	NOUN
dti-1334	577	37	,	,	PUNCT
dti-1334	577	38	arciero	arciero	NOUN
dti-1334	577	39	,	,	PUNCT
dti-1334	577	40	c.	c.	PROPN
dti-1334	577	41	,	,	PUNCT
dti-1334	577	42	brzeski	brzeski	PROPN
dti-1334	577	43	,	,	PUNCT
dti-1334	577	44	h.	h.	PROPN
dti-1334	577	45	,	,	PUNCT
dti-1334	577	46	hooke	hooke	PROPN
dti-1334	577	47	,	,	PUNCT
dti-1334	577	48	j.	j.	PROPN
dti-1334	577	49	and	and	CCONJ
dti-1334	577	50	shriver	shriver	PROPN
dti-1334	577	51	,	,	PUNCT
dti-1334	577	52	c.	c.	PROPN
dti-1334	577	53	2003	2003	NUM
dti-1334	577	54	.	.	PUNCT
dti-1334	578	1	high	high	ADJ
dti-1334	578	2	-	-	PUNCT
dti-1334	578	3	throughput	throughput	NOUN
dti-1334	578	4	proteomic	proteomic	ADJ
dti-1334	578	5	analysis	analysis	NOUN
dti-1334	578	6	of	of	ADP
dti-1334	578	7	human	human	ADJ
dti-1334	578	8	infi	infi	PROPN
dti-1334	578	9	ltrating	ltrate	VERB
dti-1334	578	10	ductal	ductal	ADJ
dti-1334	578	11	carcinoma	carcinoma	NOUN
dti-1334	578	12	of	of	ADP
dti-1334	578	13	the	the	DET
dti-1334	578	14	breast	breast	NOUN
dti-1334	578	15	.	.	PUNCT
dti-1334	579	1	proteomics	proteomic	NOUN
dti-1334	579	2	,	,	PUNCT
dti-1334	579	3	3:1863–73	3:1863–73	PROPN
dti-1334	579	4	.	.	PUNCT
dti-1334	580	1	stasyk	stasyk	PROPN
dti-1334	580	2	,	,	PUNCT
dti-1334	580	3	t.	t.	PROPN
dti-1334	580	4	,	,	PUNCT
dti-1334	580	5	morandell	morandell	NOUN
dti-1334	580	6	,	,	PUNCT
dti-1334	580	7	s.	s.	PROPN
dti-1334	580	8	,	,	PUNCT
dti-1334	580	9	bakry	bakry	PROPN
dti-1334	580	10	,	,	PUNCT
dti-1334	580	11	r.	r.	PROPN
dti-1334	580	12	,	,	PUNCT
dti-1334	580	13	feuerstein	feuerstein	NOUN
dti-1334	580	14	,	,	PUNCT
dti-1334	580	15	i.	i.	PROPN
dti-1334	580	16	,	,	PUNCT
dti-1334	580	17	huck	huck	PROPN
dti-1334	580	18	,	,	PUNCT
dti-1334	580	19	c.w	c.w	PROPN
dti-1334	580	20	.	.	PROPN
dti-1334	580	21	,	,	PUNCT
dti-1334	580	22	stecher	stecher	PROPN
dti-1334	580	23	,	,	PUNCT
dti-1334	580	24	g.	g.	PROPN
dti-1334	580	25	,	,	PUNCT
dti-1334	580	26	bonn	bonn	PROPN
dti-1334	580	27	,	,	PUNCT
dti-1334	580	28	g.k	g.k	PROPN
dti-1334	580	29	.	.	PROPN
dti-1334	580	30	and	and	CCONJ
dti-1334	580	31	huber	huber	PROPN
dti-1334	580	32	,	,	PUNCT
dti-1334	580	33	l.a	l.a	PROPN
dti-1334	580	34	.	.	PROPN
dti-1334	580	35	2005	2005	NUM
dti-1334	580	36	.	.	PUNCT
dti-1334	581	1	quantitative	quantitative	ADJ
dti-1334	581	2	detection	detection	NOUN
dti-1334	581	3	of	of	ADP
dti-1334	581	4	phosphoproteins	phosphoprotein	NOUN
dti-1334	581	5	by	by	ADP
dti-1334	581	6	combination	combination	NOUN
dti-1334	581	7	of	of	ADP
dti-1334	581	8	two	two	NUM
dti-1334	581	9	-	-	PUNCT
dti-1334	581	10	dimensional	dimensional	ADJ
dti-1334	581	11	difference	difference	NOUN
dti-1334	581	12	gel	gel	NOUN
dti-1334	581	13	electrophoresis	electrophoresis	NOUN
dti-1334	581	14	and	and	CCONJ
dti-1334	581	15	phosphospecifi	phosphospecifi	NOUN
dti-1334	581	16	c	c	PROPN
dti-1334	581	17	fl	fl	NUM
dti-1334	581	18	uorescent	uorescent	ADJ
dti-1334	581	19	staining	stain	VERB
dti-1334	581	20	.	.	PUNCT
dti-1334	582	1	electrophoresis	electrophoresis	NOUN
dti-1334	582	2	,	,	PUNCT
dti-1334	582	3	26:2850–4	26:2850–4	NUM
dti-1334	582	4	.	.	PUNCT
dti-1334	583	1	stein	stein	PROPN
dti-1334	583	2	,	,	PUNCT
dti-1334	583	3	u.	u.	PROPN
dti-1334	583	4	,	,	PUNCT
dti-1334	583	5	stege	stege	PROPN
dti-1334	583	6	,	,	PUNCT
dti-1334	583	7	alexandra	alexandra	PROPN
dti-1334	583	8	.	.	PROPN
dti-1334	583	9	,	,	PUNCT
dti-1334	583	10	walther	walther	NOUN
dti-1334	583	11	,	,	PUNCT
dti-1334	583	12	wolfgang	wolfgang	PROPN
dti-1334	583	13	.	.	PROPN
dti-1334	583	14	,	,	PUNCT
dti-1334	583	15	lage	lage	PROPN
dti-1334	583	16	,	,	PUNCT
dti-1334	583	17	hermann	hermann	PROPN
dti-1334	583	18	.	.	PROPN
dti-1334	583	19	2006	2006	NUM
dti-1334	583	20	.	.	PUNCT
dti-1334	584	1	complete	complete	ADJ
dti-1334	584	2	in	in	ADP
dti-1334	584	3	vivo	vivo	ADJ
dti-1334	584	4	reversal	reversal	NOUN
dti-1334	584	5	of	of	ADP
dti-1334	584	6	the	the	DET
dti-1334	584	7	multidrug	multidrug	NOUN
dti-1334	584	8	resistance	resistance	NOUN
dti-1334	584	9	(	(	PUNCT
dti-1334	584	10	mdr	mdr	NOUN
dti-1334	584	11	)	)	PUNCT
dti-1334	584	12	phenotype	phenotype	NOUN
dti-1334	584	13	in	in	ADP
dti-1334	584	14	a	a	DET
dti-1334	584	15	breast	breast	NOUN
dti-1334	584	16	cancer	cancer	NOUN
dti-1334	584	17	model	model	NOUN
dti-1334	584	18	by	by	ADP
dti-1334	584	19	jet	jet	NOUN
dti-1334	584	20	-	-	PUNCT
dti-1334	584	21	injection	injection	NOUN
dti-1334	584	22	of	of	ADP
dti-1334	584	23	anti	anti	ADJ
dti-1334	584	24	-	-	ADJ
dti-1334	584	25	mdr1	mdr1	ADJ
dti-1334	584	26	short	short	ADJ
dti-1334	584	27	hairpin	hairpin	NOUN
dti-1334	584	28	rna	rna	NOUN
dti-1334	584	29	-	-	PUNCT
dti-1334	584	30	encoding	encode	VERB
dti-1334	584	31	plasmid	plasmid	ADJ
dti-1334	584	32	dna	dna	NOUN
dti-1334	584	33	.	.	PUNCT
dti-1334	585	1	molecular	molecular	ADJ
dti-1334	585	2	therapy	therapy	NOUN
dti-1334	585	3	,	,	PUNCT
dti-1334	585	4	in	in	ADP
dti-1334	585	5	press	press	NOUN
dti-1334	585	6	.	.	PUNCT
dti-1334	586	1	szalowska	szalowska	PROPN
dti-1334	586	2	,	,	PUNCT
dti-1334	586	3	e.	e.	PROPN
dti-1334	586	4	,	,	PUNCT
dti-1334	586	5	hijum	hijum	PROPN
dti-1334	586	6	,	,	PUNCT
dti-1334	586	7	s.a	s.a	PROPN
dti-1334	586	8	.	.	PROPN
dti-1334	586	9	,	,	PUNCT
dti-1334	586	10	roelofsen	roelofsen	VERB
dti-1334	586	11	,	,	PUNCT
dti-1334	586	12	h.	h.	PROPN
dti-1334	586	13	,	,	PUNCT
dti-1334	586	14	hoek	hoek	PROPN
dti-1334	586	15	,	,	PUNCT
dti-1334	586	16	a.	a.	PROPN
dti-1334	586	17	,	,	PUNCT
dti-1334	586	18	vonk	vonk	PROPN
dti-1334	586	19	,	,	PUNCT
dti-1334	586	20	r.j	r.j	PROPN
dti-1334	586	21	.	.	PROPN
dti-1334	586	22	and	and	CCONJ
dti-1334	586	23	meerman	meerman	PROPN
dti-1334	586	24	,	,	PUNCT
dti-1334	586	25	g.j	g.j	PROPN
dti-1334	586	26	.	.	PROPN
dti-1334	586	27	2007	2007	NUM
dti-1334	586	28	.	.	PUNCT
dti-1334	587	1	fractional	fractional	ADJ
dti-1334	587	2	factorial	factorial	ADJ
dti-1334	587	3	design	design	NOUN
dti-1334	587	4	for	for	ADP
dti-1334	587	5	optimization	optimization	NOUN
dti-1334	587	6	of	of	ADP
dti-1334	587	7	the	the	DET
dti-1334	587	8	seldi	seldi	PROPN
dti-1334	587	9	protocol	protocol	NOUN
dti-1334	587	10	for	for	ADP
dti-1334	587	11	human	human	ADJ
dti-1334	587	12	adipose	adipose	ADJ
dti-1334	587	13	tissue	tissue	NOUN
dti-1334	587	14	culture	culture	NOUN
dti-1334	587	15	media	medium	NOUN
dti-1334	587	16	.	.	PUNCT
dti-1334	588	1	biotechnol	biotechnol	PROPN
dti-1334	588	2	.	.	PUNCT
dti-1334	589	1	prog	prog	PROPN
dti-1334	589	2	.	.	PROPN
dti-1334	590	1	,	,	PUNCT
dti-1334	590	2	23:217–24	23:217–24	PROPN
dti-1334	590	3	.	.	PUNCT
dti-1334	591	1	tannu	tannu	PROPN
dti-1334	591	2	,	,	PUNCT
dti-1334	591	3	n.s	n.s	PROPN
dti-1334	591	4	.	.	PROPN
dti-1334	591	5	and	and	CCONJ
dti-1334	591	6	hemby	hemby	PROPN
dti-1334	591	7	,	,	PUNCT
dti-1334	591	8	s.e	s.e	PROPN
dti-1334	591	9	.	.	PROPN
dti-1334	591	10	2006a	2006a	NOUN
dti-1334	591	11	.	.	PUNCT
dti-1334	592	1	methods	method	NOUN
dti-1334	592	2	for	for	ADP
dti-1334	592	3	proteomics	proteomic	NOUN
dti-1334	592	4	in	in	ADP
dti-1334	592	5	neuroscience	neuroscience	NOUN
dti-1334	592	6	.	.	PUNCT
dti-1334	593	1	prog	prog	NOUN
dti-1334	593	2	.	.	PUNCT
dti-1334	594	1	brain	brain	NOUN
dti-1334	594	2	res	re	NOUN
dti-1334	594	3	.	.	PUNCT
dti-1334	594	4	,	,	PUNCT
dti-1334	595	1	158:41–82	158:41–82	X
dti-1334	595	2	.	.	PROPN
dti-1334	595	3	66	66	NUM
dti-1334	596	1	shen	shen	NOUN
dti-1334	596	2	et	et	PROPN
dti-1334	596	3	al	al	PROPN
dti-1334	596	4	drug	drug	PROPN
dti-1334	596	5	target	target	NOUN
dti-1334	596	6	insights	insight	NOUN
dti-1334	596	7	2008:3	2008:3	NUM
dti-1334	596	8	tannu	tannu	NOUN
dti-1334	596	9	,	,	PUNCT
dti-1334	596	10	n.s	n.s	PROPN
dti-1334	596	11	.	.	PROPN
dti-1334	596	12	and	and	CCONJ
dti-1334	596	13	hemby	hemby	PROPN
dti-1334	596	14	,	,	PUNCT
dti-1334	596	15	s.e	s.e	PROPN
dti-1334	596	16	.	.	PROPN
dti-1334	596	17	2006b	2006b	NUM
dti-1334	596	18	.	.	PUNCT
dti-1334	597	1	two	two	NUM
dti-1334	597	2	-	-	PUNCT
dti-1334	597	3	dimensional	dimensional	ADJ
dti-1334	597	4	fluorescence	fluorescence	NOUN
dti-1334	597	5	difference	difference	NOUN
dti-1334	597	6	gel	gel	NOUN
dti-1334	597	7	electrophoresis	electrophoresis	NOUN
dti-1334	597	8	for	for	ADP
dti-1334	597	9	comparative	comparative	ADJ
dti-1334	597	10	proteomics	proteomic	NOUN
dti-1334	597	11	profi	profi	PROPN
dti-1334	597	12	ling	ling	PROPN
dti-1334	597	13	.	.	PUNCT
dti-1334	598	1	nat	nat	PROPN
dti-1334	598	2	.	.	PUNCT
dti-1334	599	1	protoc	protoc	VERB
dti-1334	599	2	.	.	PUNCT
dti-1334	600	1	,	,	PUNCT
dti-1334	601	1	1:1732–42	1:1732–42	NUM
dti-1334	601	2	.	.	PUNCT
dti-1334	602	1	turecek	turecek	PROPN
dti-1334	602	2	,	,	PUNCT
dti-1334	602	3	f.	f.	PROPN
dti-1334	602	4	2002	2002	NUM
dti-1334	602	5	.	.	PUNCT
dti-1334	603	1	mass	mass	ADJ
dti-1334	603	2	spectrometry	spectrometry	NOUN
dti-1334	603	3	in	in	ADP
dti-1334	603	4	coupling	couple	VERB
dti-1334	603	5	with	with	ADP
dti-1334	603	6	affi	affi	PROPN
dti-1334	603	7	nity	nity	NOUN
dti-1334	603	8	capture	capture	NOUN
dti-1334	603	9	-	-	PUNCT
dti-1334	603	10	release	release	NOUN
dti-1334	603	11	and	and	CCONJ
dti-1334	603	12	isotope	isotope	NOUN
dti-1334	603	13	-	-	PUNCT
dti-1334	603	14	coded	code	VERB
dti-1334	603	15	affi	affi	ADJ
dti-1334	603	16	nity	nity	NOUN
dti-1334	603	17	tags	tag	NOUN
dti-1334	603	18	for	for	ADP
dti-1334	603	19	quantitative	quantitative	ADJ
dti-1334	603	20	protein	protein	NOUN
dti-1334	603	21	analysis	analysis	NOUN
dti-1334	603	22	.	.	PUNCT
dti-1334	604	1	j.	j.	PROPN
dti-1334	604	2	mass	mass	PROPN
dti-1334	604	3	spectrom	spectrom	PROPN
dti-1334	604	4	.	.	PUNCT
dti-1334	604	5	,	,	PUNCT
dti-1334	605	1	37:1–14	37:1–14	X
dti-1334	605	2	.	.	PUNCT
dti-1334	606	1	unlu	unlu	ADJ
dti-1334	606	2	,	,	PUNCT
dti-1334	606	3	m.	m.	NOUN
dti-1334	606	4	,	,	PUNCT
dti-1334	606	5	morgan	morgan	PROPN
dti-1334	606	6	,	,	PUNCT
dti-1334	606	7	m.e	m.e	PROPN
dti-1334	606	8	.	.	PROPN
dti-1334	606	9	and	and	CCONJ
dti-1334	606	10	minden	minden	PROPN
dti-1334	606	11	,	,	PUNCT
dti-1334	606	12	j.s	j.s	PROPN
dti-1334	606	13	.	.	PROPN
dti-1334	606	14	1997	1997	NUM
dti-1334	606	15	.	.	PUNCT
dti-1334	607	1	difference	difference	NOUN
dti-1334	607	2	gel	gel	NOUN
dti-1334	607	3	electrophoresis	electrophoresis	NOUN
dti-1334	607	4	:	:	PUNCT
dti-1334	607	5	a	a	DET
dti-1334	607	6	single	single	ADJ
dti-1334	607	7	gel	gel	NOUN
dti-1334	607	8	method	method	NOUN
dti-1334	607	9	for	for	ADP
dti-1334	607	10	detecting	detect	VERB
dti-1334	607	11	changes	change	NOUN
dti-1334	607	12	in	in	ADP
dti-1334	607	13	protein	protein	NOUN
dti-1334	607	14	extracts	extract	NOUN
dti-1334	607	15	.	.	PUNCT
dti-1334	608	1	electrophoresis	electrophoresis	NOUN
dti-1334	608	2	,	,	PUNCT
dti-1334	608	3	18:2071–7	18:2071–7	NUM
dti-1334	608	4	.	.	PUNCT
dti-1334	609	1	uttamchandani	uttamchandani	NOUN
dti-1334	609	2	,	,	PUNCT
dti-1334	609	3	m.	m.	NOUN
dti-1334	609	4	,	,	PUNCT
dti-1334	609	5	wang	wang	PROPN
dti-1334	609	6	,	,	PUNCT
dti-1334	609	7	j.	j.	PROPN
dti-1334	609	8	and	and	CCONJ
dti-1334	609	9	yao	yao	PROPN
dti-1334	609	10	,	,	PUNCT
dti-1334	609	11	s.q	s.q	PROPN
dti-1334	609	12	.	.	PROPN
dti-1334	609	13	2006	2006	NUM
dti-1334	609	14	.	.	PUNCT
dti-1334	610	1	protein	protein	NOUN
dti-1334	610	2	and	and	CCONJ
dti-1334	610	3	small	small	ADJ
dti-1334	610	4	molecule	molecule	NOUN
dti-1334	610	5	microarrays	microarray	NOUN
dti-1334	610	6	:	:	PUNCT
dti-1334	610	7	powerful	powerful	ADJ
dti-1334	610	8	tools	tool	NOUN
dti-1334	610	9	for	for	ADP
dti-1334	610	10	high	high	ADJ
dti-1334	610	11	-	-	PUNCT
dti-1334	610	12	throughput	throughput	NOUN
dti-1334	610	13	proteomics	proteomic	NOUN
dti-1334	610	14	.	.	PUNCT
dti-1334	611	1	mol	mol	PROPN
dti-1334	611	2	.	.	PUNCT
dti-1334	612	1	biosyst	biosyst	PROPN
dti-1334	612	2	.	.	PUNCT
dti-1334	612	3	,	,	PUNCT
dti-1334	613	1	2:58–68	2:58–68	PROPN
dti-1334	613	2	.	.	PUNCT
dti-1334	613	3	vlassov	vlassov	PROPN
dti-1334	613	4	,	,	PUNCT
dti-1334	613	5	a.v	a.v	PROPN
dti-1334	613	6	.	.	PROPN
dti-1334	613	7	,	,	PUNCT
dti-1334	613	8	korba	korba	PROPN
dti-1334	613	9	,	,	PUNCT
dti-1334	613	10	b.	b.	PROPN
dti-1334	613	11	,	,	PUNCT
dti-1334	613	12	farrar	farrar	PROPN
dti-1334	613	13	,	,	PUNCT
dti-1334	613	14	k.	k.	PROPN
dti-1334	613	15	,	,	PUNCT
dti-1334	613	16	mukerjee	mukerjee	PROPN
dti-1334	613	17	,	,	PUNCT
dti-1334	613	18	s.	s.	PROPN
dti-1334	613	19	,	,	PUNCT
dti-1334	613	20	seyhan	seyhan	PROPN
dti-1334	613	21	,	,	PUNCT
dti-1334	613	22	a.a	a.a	PROPN
dti-1334	613	23	.	.	PROPN
dti-1334	613	24	,	,	PUNCT
dti-1334	613	25	ilves	ilve	NOUN
dti-1334	613	26	,	,	PUNCT
dti-1334	613	27	h.	h.	PROPN
dti-1334	613	28	,	,	PUNCT
dti-1334	613	29	kaspar	kaspar	PROPN
dti-1334	613	30	,	,	PUNCT
dti-1334	613	31	r.l	r.l	PROPN
dti-1334	613	32	.	.	PROPN
dti-1334	613	33	,	,	PUNCT
dti-1334	613	34	leake	leake	PROPN
dti-1334	613	35	,	,	PUNCT
dti-1334	613	36	d.	d.	PROPN
dti-1334	613	37	,	,	PUNCT
dti-1334	613	38	kazakov	kazakov	PROPN
dti-1334	613	39	,	,	PUNCT
dti-1334	613	40	s.a	s.a	PROPN
dti-1334	613	41	.	.	PROPN
dti-1334	613	42	and	and	CCONJ
dti-1334	613	43	johnston	johnston	PROPN
dti-1334	613	44	,	,	PUNCT
dti-1334	613	45	b.h	b.h	PROPN
dti-1334	613	46	.	.	PROPN
dti-1334	613	47	2007	2007	NUM
dti-1334	613	48	.	.	PUNCT
dti-1334	614	1	shrnas	shrna	VERB
dti-1334	614	2	targeting	target	VERB
dti-1334	614	3	hepatitis	hepatitis	NOUN
dti-1334	614	4	c	c	NOUN
dti-1334	614	5	:	:	PUNCT
dti-1334	614	6	effects	effect	NOUN
dti-1334	614	7	of	of	ADP
dti-1334	614	8	sequence	sequence	NOUN
dti-1334	614	9	and	and	CCONJ
dti-1334	614	10	structural	structural	ADJ
dti-1334	614	11	features	feature	NOUN
dti-1334	614	12	,	,	PUNCT
dti-1334	614	13	and	and	CCONJ
dti-1334	614	14	comparision	comparision	NOUN
dti-1334	614	15	with	with	ADP
dti-1334	614	16	sirna	sirna	PROPN
dti-1334	614	17	.	.	PUNCT
dti-1334	615	1	oligonucleotides	oligonucleotide	NOUN
dti-1334	615	2	,	,	PUNCT
dti-1334	615	3	17:223–36	17:223–36	NUM
dti-1334	615	4	.	.	PUNCT
dti-1334	616	1	vogel	vogel	PROPN
dti-1334	616	2	,	,	PUNCT
dti-1334	616	3	a.	a.	PROPN
dti-1334	616	4	,	,	PUNCT
dti-1334	616	5	horneffer	horneffer	VERB
dti-1334	616	6	,	,	PUNCT
dti-1334	616	7	v.	v.	PROPN
dti-1334	616	8	,	,	PUNCT
dti-1334	616	9	lorenz	lorenz	PROPN
dti-1334	616	10	,	,	PUNCT
dti-1334	616	11	k.	k.	PROPN
dti-1334	616	12	,	,	PUNCT
dti-1334	616	13	linz	linz	PROPN
dti-1334	616	14	,	,	PUNCT
dti-1334	616	15	n.	n.	NOUN
dti-1334	616	16	,	,	PUNCT
dti-1334	616	17	huttmann	huttmann	PROPN
dti-1334	616	18	,	,	PUNCT
dti-1334	616	19	g.	g.	PROPN
dti-1334	616	20	and	and	CCONJ
dti-1334	616	21	gebert	gebert	PROPN
dti-1334	616	22	,	,	PUNCT
dti-1334	616	23	a.	a.	NOUN
dti-1334	616	24	2007	2007	NUM
dti-1334	616	25	.	.	PUNCT
dti-1334	617	1	principles	principle	NOUN
dti-1334	617	2	of	of	ADP
dti-1334	617	3	laser	laser	NOUN
dti-1334	617	4	microdissection	microdissection	NOUN
dti-1334	617	5	and	and	CCONJ
dti-1334	617	6	catapulting	catapulting	NOUN
dti-1334	617	7	of	of	ADP
dti-1334	617	8	histologic	histologic	ADJ
dti-1334	617	9	specimens	specimen	NOUN
dti-1334	617	10	and	and	CCONJ
dti-1334	617	11	live	live	ADJ
dti-1334	617	12	cells	cell	NOUN
dti-1334	617	13	.	.	PUNCT
dti-1334	618	1	methods	method	NOUN
dti-1334	618	2	cell	cell	NOUN
dti-1334	618	3	.	.	PUNCT
dti-1334	619	1	biol	biol	PROPN
dti-1334	619	2	.	.	PUNCT
dti-1334	619	3	,	,	PUNCT
dti-1334	619	4	82:153–205	82:153–205	NUM
dti-1334	619	5	.	.	PUNCT
dti-1334	620	1	volpi	volpi	PROPN
dti-1334	620	2	,	,	PUNCT
dti-1334	620	3	a.	a.	PROPN
dti-1334	620	4	,	,	PUNCT
dti-1334	620	5	nanni	nanni	PROPN
dti-1334	620	6	,	,	PUNCT
dti-1334	620	7	o.	o.	PROPN
dti-1334	620	8	,	,	PUNCT
dti-1334	620	9	de	de	PROPN
dti-1334	620	10	paola	paola	PROPN
dti-1334	620	11	,	,	PUNCT
dti-1334	620	12	f.	f.	PROPN
dti-1334	620	13	,	,	PUNCT
dti-1334	620	14	granato	granato	PROPN
dti-1334	620	15	,	,	PUNCT
dti-1334	620	16	a.m.	a.m.	ADV
dti-1334	620	17	,	,	PUNCT
dti-1334	620	18	mangia	mangia	PROPN
dti-1334	620	19	,	,	PUNCT
dti-1334	620	20	a.	a.	NOUN
dti-1334	620	21	,	,	PUNCT
dti-1334	620	22	monti	monti	PROPN
dti-1334	620	23	,	,	PUNCT
dti-1334	620	24	f.	f.	PROPN
dti-1334	620	25	,	,	PUNCT
dti-1334	620	26	schittulli	schittulli	PROPN
dti-1334	620	27	,	,	PUNCT
dti-1334	620	28	f.	f.	PROPN
dti-1334	620	29	,	,	PUNCT
dti-1334	620	30	de	de	PROPN
dti-1334	620	31	lena	lena	PROPN
dti-1334	620	32	,	,	PUNCT
dti-1334	620	33	m.	m.	NOUN
dti-1334	620	34	,	,	PUNCT
dti-1334	620	35	scarpi	scarpi	NOUN
dti-1334	620	36	,	,	PUNCT
dti-1334	620	37	e.	e.	PROPN
dti-1334	620	38	,	,	PUNCT
dti-1334	620	39	rosetti	rosetti	ADJ
dti-1334	620	40	,	,	PUNCT
dti-1334	620	41	p.	p.	PROPN
dti-1334	620	42	,	,	PUNCT
dti-1334	620	43	monti	monti	PROPN
dti-1334	620	44	,	,	PUNCT
dti-1334	620	45	m.	m.	NOUN
dti-1334	620	46	,	,	PUNCT
dti-1334	620	47	gianni	gianni	PROPN
dti-1334	620	48	,	,	PUNCT
dti-1334	620	49	l.	l.	PROPN
dti-1334	620	50	,	,	PUNCT
dti-1334	620	51	amadori	amadori	PROPN
dti-1334	620	52	,	,	PUNCT
dti-1334	620	53	d.	d.	PROPN
dti-1334	620	54	and	and	CCONJ
dti-1334	620	55	paradiso	paradiso	PROPN
dti-1334	620	56	,	,	PUNCT
dti-1334	620	57	a.	a.	NOUN
dti-1334	620	58	2003	2003	NUM
dti-1334	620	59	.	.	PUNCT
dti-1334	621	1	j.	j.	PROPN
dti-1334	621	2	clin	clin	PROPN
dti-1334	621	3	.	.	PUNCT
dti-1334	622	1	oncol	oncol	PROPN
dti-1334	622	2	.	.	PUNCT
dti-1334	622	3	,	,	PUNCT
dti-1334	622	4	21:2708–12	21:2708–12	PROPN
dti-1334	622	5	.	.	PUNCT
dti-1334	623	1	von	von	PROPN
dti-1334	623	2	eggeling	eggeling	PROPN
dti-1334	623	3	,	,	PUNCT
dti-1334	623	4	f.	f.	PROPN
dti-1334	623	5	,	,	PUNCT
dti-1334	623	6	melle	melle	PROPN
dti-1334	623	7	,	,	PUNCT
dti-1334	623	8	c.	c.	PROPN
dti-1334	623	9	and	and	CCONJ
dti-1334	623	10	ernst	ernst	PROPN
dti-1334	623	11	,	,	PUNCT
dti-1334	623	12	g.	g.	PROPN
dti-1334	623	13	2007	2007	NUM
dti-1334	623	14	.	.	PUNCT
dti-1334	624	1	microdissecting	microdissecte	VERB
dti-1334	624	2	the	the	DET
dti-1334	624	3	proteome	proteome	NOUN
dti-1334	624	4	.	.	PUNCT
dti-1334	625	1	proteomics	proteomic	NOUN
dti-1334	625	2	,	,	PUNCT
dti-1334	625	3	7:2729–37	7:2729–37	NOUN
dti-1334	625	4	.	.	PUNCT
dti-1334	626	1	wu	wu	PROPN
dti-1334	626	2	,	,	PUNCT
dti-1334	626	3	c.c	c.c	PROPN
dti-1334	626	4	.	.	PROPN
dti-1334	626	5	and	and	CCONJ
dti-1334	626	6	maccoss	maccoss	PROPN
dti-1334	626	7	,	,	PUNCT
dti-1334	626	8	m.j	m.j	PROPN
dti-1334	626	9	.	.	PROPN
dti-1334	626	10	2002	2002	NUM
dti-1334	626	11	.	.	PUNCT
dti-1334	627	1	shotgun	shotgun	NOUN
dti-1334	627	2	proteomics	proteomic	NOUN
dti-1334	627	3	:	:	PUNCT
dti-1334	627	4	tools	tool	NOUN
dti-1334	627	5	for	for	ADP
dti-1334	627	6	the	the	DET
dti-1334	627	7	analysis	analysis	NOUN
dti-1334	627	8	of	of	ADP
dti-1334	627	9	complex	complex	ADJ
dti-1334	627	10	biological	biological	ADJ
dti-1334	627	11	systems	system	NOUN
dti-1334	627	12	.	.	PUNCT
dti-1334	628	1	curr	curr	PROPN
dti-1334	628	2	.	.	PUNCT
dti-1334	629	1	opin	opin	NOUN
dti-1334	629	2	.	.	PUNCT
dti-1334	630	1	mol	mol	PROPN
dti-1334	630	2	.	.	PROPN
dti-1334	631	1	ther	ther	PROPN
dti-1334	631	2	.	.	PUNCT
dti-1334	631	3	,	,	PUNCT
dti-1334	632	1	4:242–50	4:242–50	NOUN
dti-1334	632	2	.	.	PUNCT
dti-1334	632	3	wu	wu	PROPN
dti-1334	632	4	,	,	PUNCT
dti-1334	632	5	h.	h.	PROPN
dti-1334	632	6	,	,	PUNCT
dti-1334	632	7	pan	pan	PROPN
dti-1334	632	8	,	,	PUNCT
dti-1334	632	9	c.l	c.l	PROPN
dti-1334	632	10	.	.	PROPN
dti-1334	632	11	,	,	PUNCT
dti-1334	632	12	yao	yao	PROPN
dti-1334	632	13	,	,	PUNCT
dti-1334	632	14	y.c	y.c	PROPN
dti-1334	632	15	.	.	PROPN
dti-1334	632	16	,	,	PUNCT
dti-1334	632	17	chang	chang	PROPN
dti-1334	632	18	,	,	PUNCT
dti-1334	632	19	s.s	s.s	PROPN
dti-1334	632	20	.	.	PROPN
dti-1334	632	21	,	,	PUNCT
dti-1334	632	22	li	li	PROPN
dti-1334	632	23	,	,	PUNCT
dti-1334	632	24	s.l	s.l	PROPN
dti-1334	632	25	.	.	PROPN
dti-1334	632	26	and	and	CCONJ
dti-1334	632	27	wu	wu	PROPN
dti-1334	632	28	,	,	PUNCT
dti-1334	632	29	t.f	t.f	PROPN
dti-1334	632	30	.	.	PROPN
dti-1334	632	31	2006	2006	NUM
dti-1334	632	32	.	.	PUNCT
dti-1334	633	1	proteomic	proteomic	ADJ
dti-1334	633	2	analysis	analysis	NOUN
dti-1334	633	3	of	of	ADP
dti-1334	633	4	the	the	DET
dti-1334	633	5	effect	effect	NOUN
dti-1334	633	6	of	of	ADP
dti-1334	633	7	antrodia	antrodia	PROPN
dti-1334	633	8	camphorata	camphorata	PROPN
dti-1334	633	9	extract	extract	NOUN
dti-1334	633	10	on	on	ADP
dti-1334	633	11	human	human	ADJ
dti-1334	633	12	lung	lung	NOUN
dti-1334	633	13	cancer	cancer	NOUN
dti-1334	633	14	a549	a549	PROPN
dti-1334	633	15	cell	cell	NOUN
dti-1334	633	16	.	.	PUNCT
dti-1334	634	1	proteomics	proteomic	NOUN
dti-1334	634	2	,	,	PUNCT
dti-1334	634	3	6:826–35	6:826–35	NUM
dti-1334	634	4	.	.	PUNCT
dti-1334	634	5	wu	wu	PROPN
dti-1334	634	6	,	,	PUNCT
dti-1334	634	7	t.l	t.l	PROPN
dti-1334	634	8	.	.	PROPN
dti-1334	634	9	2006	2006	NUM
dti-1334	634	10	.	.	PUNCT
dti-1334	635	1	two	two	NUM
dti-1334	635	2	-	-	PUNCT
dti-1334	635	3	dimensional	dimensional	ADJ
dti-1334	635	4	difference	difference	NOUN
dti-1334	635	5	gel	gel	NOUN
dti-1334	635	6	electrophoresis	electrophoresis	NOUN
dti-1334	635	7	.	.	PUNCT
dti-1334	636	1	methods	method	NOUN
dti-1334	636	2	mol	mol	PROPN
dti-1334	636	3	.	.	PUNCT
dti-1334	637	1	biol	biol	PROPN
dti-1334	637	2	.	.	PUNCT
dti-1334	637	3	,	,	PUNCT
dti-1334	637	4	328:71–95	328:71–95	X
dti-1334	637	5	.	.	PUNCT
dti-1334	637	6	yan	yan	PROPN
dti-1334	637	7	,	,	PUNCT
dti-1334	637	8	j.x	j.x	PROPN
dti-1334	637	9	.	.	PROPN
dti-1334	637	10	,	,	PUNCT
dti-1334	637	11	sanchez	sanchez	PROPN
dti-1334	637	12	,	,	PUNCT
dti-1334	637	13	j.c	j.c	PROPN
dti-1334	637	14	.	.	PROPN
dti-1334	637	15	,	,	PUNCT
dti-1334	637	16	rouge	rouge	PROPN
dti-1334	637	17	,	,	PUNCT
dti-1334	637	18	v.	v.	PROPN
dti-1334	637	19	,	,	PUNCT
dti-1334	637	20	williams	williams	PROPN
dti-1334	637	21	,	,	PUNCT
dti-1334	637	22	k.l	k.l	PROPN
dti-1334	637	23	.	.	PROPN
dti-1334	637	24	and	and	CCONJ
dti-1334	637	25	hochstrasser	hochstrasser	PROPN
dti-1334	637	26	,	,	PUNCT
dti-1334	637	27	d.f	d.f	PROPN
dti-1334	637	28	.	.	PROPN
dti-1334	637	29	1999	1999	NUM
dti-1334	637	30	.	.	PUNCT
dti-1334	638	1	modifi	modifi	PROPN
dti-1334	638	2	ed	ed	PROPN
dti-1334	638	3	immobilized	immobilize	VERB
dti-1334	638	4	ph	ph	PROPN
dti-1334	638	5	gradient	gradient	NOUN
dti-1334	638	6	gel	gel	PROPN
dti-1334	638	7	strip	strip	NOUN
dti-1334	638	8	equilibration	equilibration	NOUN
dti-1334	638	9	procedure	procedure	NOUN
dti-1334	638	10	in	in	ADP
dti-1334	638	11	swiss-2dpage	swiss-2dpage	PROPN
dti-1334	638	12	protocols	protocol	NOUN
dti-1334	638	13	.	.	PUNCT
dti-1334	639	1	electrophoresis	electrophoresis	NOUN
dti-1334	639	2	,	,	PUNCT
dti-1334	639	3	20:723–6	20:723–6	NUM
dti-1334	639	4	.	.	PUNCT
dti-1334	640	1	young	young	ADJ
dti-1334	640	2	,	,	PUNCT
dti-1334	640	3	t.	t.	PROPN
dti-1334	640	4	,	,	PUNCT
dti-1334	640	5	mei	mei	PROPN
dti-1334	640	6	,	,	PUNCT
dti-1334	640	7	f.	f.	PROPN
dti-1334	640	8	,	,	PUNCT
dti-1334	640	9	liu	liu	PROPN
dti-1334	640	10	,	,	PUNCT
dti-1334	640	11	j.	j.	PROPN
dti-1334	640	12	,	,	PUNCT
dti-1334	640	13	bast	bast	NOUN
dti-1334	640	14	,	,	PUNCT
dti-1334	640	15	r.c	r.c	PROPN
dti-1334	640	16	.	.	PROPN
dti-1334	640	17	,	,	PUNCT
dti-1334	640	18	kurosky	kurosky	PROPN
dti-1334	640	19	,	,	PUNCT
dti-1334	640	20	a.	a.	PROPN
dti-1334	640	21	and	and	CCONJ
dti-1334	640	22	cheng	cheng	PROPN
dti-1334	640	23	,	,	PUNCT
dti-1334	640	24	x.	x.	NOUN
dti-1334	640	25	2005	2005	NUM
dti-1334	640	26	.	.	PUNCT
dti-1334	641	1	proteomics	proteomic	NOUN
dti-1334	641	2	analysis	analysis	NOUN
dti-1334	641	3	of	of	ADP
dti-1334	641	4	h	h	NOUN
dti-1334	641	5	-	-	PUNCT
dti-1334	641	6	ras	ra	VERB
dti-1334	641	7	-	-	PUNCT
dti-1334	641	8	mediated	mediate	VERB
dti-1334	641	9	oncogenic	oncogenic	ADJ
dti-1334	641	10	transformation	transformation	NOUN
dti-1334	641	11	in	in	ADP
dti-1334	641	12	a	a	DET
dti-1334	641	13	genetically	genetically	ADV
dti-1334	641	14	defi	defi	NOUN
dti-1334	641	15	ned	ned	PROPN
dti-1334	641	16	human	human	ADJ
dti-1334	641	17	ovarian	ovarian	ADJ
dti-1334	641	18	cancer	cancer	NOUN
dti-1334	641	19	model	model	NOUN
dti-1334	641	20	.	.	PUNCT
dti-1334	642	1	oncogene	oncogene	NOUN
dti-1334	642	2	,	,	PUNCT
dti-1334	642	3	24:6174–84	24:6174–84	NUM
dti-1334	642	4	.	.	PUNCT
dti-1334	643	1	yu	yu	PROPN
dti-1334	643	2	,	,	PUNCT
dti-1334	643	3	j.y	j.y	PROPN
dti-1334	643	4	.	.	PROPN
dti-1334	643	5	,	,	PUNCT
dti-1334	643	6	deruiter	deruiter	PROPN
dti-1334	643	7	,	,	PUNCT
dti-1334	643	8	s.l	s.l	PROPN
dti-1334	643	9	.	.	PROPN
dti-1334	643	10	and	and	CCONJ
dti-1334	643	11	turner	turner	PROPN
dti-1334	643	12	,	,	PUNCT
dti-1334	643	13	d.l	d.l	PROPN
dti-1334	643	14	.	.	PROPN
dti-1334	643	15	2002	2002	NUM
dti-1334	643	16	.	.	PUNCT
dti-1334	644	1	rna	rna	NOUN
dti-1334	644	2	interference	interference	NOUN
dti-1334	644	3	by	by	ADP
dti-1334	644	4	expression	expression	NOUN
dti-1334	644	5	of	of	ADP
dti-1334	644	6	short	short	ADV
dti-1334	644	7	-	-	PUNCT
dti-1334	644	8	interfering	interfere	VERB
dti-1334	644	9	rnas	rna	NOUN
dti-1334	644	10	and	and	CCONJ
dti-1334	644	11	hairpin	hairpin	VERB
dti-1334	644	12	rnas	rna	NOUN
dti-1334	644	13	in	in	ADP
dti-1334	644	14	mammalian	mammalian	ADJ
dti-1334	644	15	cells	cell	NOUN
dti-1334	644	16	.	.	PUNCT
dti-1334	645	1	proc	proc	NOUN
dti-1334	645	2	.	.	PUNCT
dti-1334	646	1	natl	natl	PROPN
dti-1334	646	2	.	.	PUNCT
dti-1334	647	1	acad	acad	PROPN
dti-1334	647	2	.	.	PUNCT
dti-1334	648	1	sci	sci	PROPN
dti-1334	648	2	.	.	PUNCT
dti-1334	648	3	u.s.a	u.s.a	PROPN
dti-1334	648	4	.	.	PROPN
dti-1334	648	5	,	,	PUNCT
dti-1334	648	6	99:6047–52	99:6047–52	NUM
dti-1334	648	7	.	.	PUNCT
dti-1334	649	1	zhang	zhang	PROPN
dti-1334	649	2	,	,	PUNCT
dti-1334	649	3	h.	h.	PROPN
dti-1334	649	4	,	,	PUNCT
dti-1334	649	5	kong	kong	PROPN
dti-1334	649	6	,	,	PUNCT
dti-1334	649	7	b.	b.	PROPN
dti-1334	649	8	,	,	PUNCT
dti-1334	649	9	qu	qu	PROPN
dti-1334	649	10	,	,	PUNCT
dti-1334	649	11	x.	x.	PROPN
dti-1334	649	12	,	,	PUNCT
dti-1334	649	13	jia	jia	PROPN
dti-1334	649	14	,	,	PUNCT
dti-1334	649	15	l.	l.	PROPN
dti-1334	649	16	,	,	PUNCT
dti-1334	649	17	deng	deng	PROPN
dti-1334	649	18	,	,	PUNCT
dti-1334	649	19	b.	b.	PROPN
dti-1334	649	20	and	and	CCONJ
dti-1334	649	21	yang	yang	PROPN
dti-1334	649	22	,	,	PUNCT
dti-1334	649	23	q.	q.	PROPN
dti-1334	649	24	2006	2006	NUM
dti-1334	649	25	.	.	PUNCT
dti-1334	650	1	biomarker	biomarker	NOUN
dti-1334	650	2	discovery	discovery	NOUN
dti-1334	650	3	for	for	ADP
dti-1334	650	4	ovarian	ovarian	ADJ
dti-1334	650	5	cancer	cancer	NOUN
dti-1334	650	6	using	use	VERB
dti-1334	650	7	seldi	seldi	PROPN
dti-1334	650	8	-	-	PUNCT
dti-1334	650	9	tof	tof	PROPN
dti-1334	650	10	-	-	PUNCT
dti-1334	650	11	ms	ms	PROPN
dti-1334	650	12	.	.	PROPN
dti-1334	650	13	gynecol	gynecol	PROPN
dti-1334	650	14	.	.	PUNCT
dti-1334	651	1	oncol	oncol	PROPN
dti-1334	651	2	.	.	PUNCT
dti-1334	651	3	,	,	PUNCT
dti-1334	651	4	102:61–6	102:61–6	NUM
dti-1334	651	5	.	.	X
dti-1334	652	1	zhou	zhou	PROPN
dti-1334	652	2	,	,	PUNCT
dti-1334	652	3	g.	g.	PROPN
dti-1334	652	4	,	,	PUNCT
dti-1334	652	5	li	li	PROPN
dti-1334	652	6	,	,	PUNCT
dti-1334	652	7	h.	h.	PROPN
dti-1334	652	8	,	,	PUNCT
dti-1334	652	9	decamp	decamp	PROPN
dti-1334	652	10	,	,	PUNCT
dti-1334	652	11	d.	d.	PROPN
dti-1334	652	12	,	,	PUNCT
dti-1334	652	13	chen	chen	PROPN
dti-1334	652	14	,	,	PUNCT
dti-1334	652	15	s.	s.	PROPN
dti-1334	652	16	,	,	PUNCT
dti-1334	652	17	shu	shu	PROPN
dti-1334	652	18	,	,	PUNCT
dti-1334	652	19	h.	h.	PROPN
dti-1334	652	20	,	,	PUNCT
dti-1334	652	21	gong	gong	PROPN
dti-1334	652	22	,	,	PUNCT
dti-1334	652	23	y.	y.	PROPN
dti-1334	652	24	,	,	PUNCT
dti-1334	652	25	flaig	flaig	PROPN
dti-1334	652	26	,	,	PUNCT
dti-1334	652	27	m.	m.	NOUN
dti-1334	652	28	,	,	PUNCT
dti-1334	652	29	gillespie	gillespie	PROPN
dti-1334	652	30	,	,	PUNCT
dti-1334	652	31	j.w	j.w	PROPN
dti-1334	652	32	.	.	PROPN
dti-1334	652	33	,	,	PUNCT
dti-1334	652	34	hu	hu	PROPN
dti-1334	652	35	,	,	PUNCT
dti-1334	652	36	n.	n.	PROPN
dti-1334	652	37	,	,	PUNCT
dti-1334	652	38	taylor	taylor	PROPN
dti-1334	652	39	,	,	PUNCT
dti-1334	652	40	p.r	p.r	PROPN
dti-1334	652	41	.	.	PROPN
dti-1334	652	42	,	,	PUNCT
dti-1334	652	43	emmert	emmert	NOUN
dti-1334	652	44	-	-	PUNCT
dti-1334	652	45	buck	buck	NOUN
dti-1334	652	46	,	,	PUNCT
dti-1334	652	47	m.r	m.r	PROPN
dti-1334	652	48	.	.	PROPN
dti-1334	652	49	,	,	PUNCT
dti-1334	652	50	liotta	liotta	PROPN
dti-1334	652	51	,	,	PUNCT
dti-1334	652	52	l.a	l.a	PROPN
dti-1334	652	53	.	.	PROPN
dti-1334	652	54	,	,	PUNCT
dti-1334	652	55	petricoin	petricoin	PROPN
dti-1334	652	56	,	,	PUNCT
dti-1334	652	57	e.f	e.f	PROPN
dti-1334	652	58	.	.	PROPN
dti-1334	652	59	and	and	CCONJ
dti-1334	652	60	zhao	zhao	PROPN
dti-1334	652	61	,	,	PUNCT
dti-1334	652	62	y.	y.	PROPN
dti-1334	652	63	2002	2002	NUM
dti-1334	652	64	.	.	PUNCT
dti-1334	653	1	2d	2d	NOUN
dti-1334	653	2	differential	differential	VERB
dti-1334	653	3	in	in	ADP
dti-1334	653	4	-	-	PUNCT
dti-1334	653	5	gel	gel	NOUN
dti-1334	653	6	electrophoresis	electrophoresis	NOUN
dti-1334	653	7	for	for	ADP
dti-1334	653	8	the	the	DET
dti-1334	653	9	identifi	identifi	PROPN
dti-1334	653	10	cation	cation	NOUN
dti-1334	653	11	of	of	ADP
dti-1334	653	12	esophageal	esophageal	ADJ
dti-1334	653	13	scans	scan	NOUN
dti-1334	653	14	cell	cell	NOUN
dti-1334	653	15	cancer	cancer	NOUN
dti-1334	653	16	-	-	PUNCT
dti-1334	653	17	specifi	specifi	PROPN
dti-1334	653	18	c	c	PROPN
dti-1334	653	19	protein	protein	NOUN
dti-1334	653	20	markers	marker	NOUN
dti-1334	653	21	.	.	PUNCT
dti-1334	654	1	mol	mol	PROPN
dti-1334	654	2	.	.	PROPN
dti-1334	654	3	cell	cell	NOUN
dti-1334	654	4	.	.	PUNCT
dti-1334	655	1	proteomics	proteomic	NOUN
dti-1334	655	2	,	,	PUNCT
dti-1334	655	3	1:117–24	1:117–24	PROPN
dti-1334	655	4	.	.	PUNCT
dti-1334	656	1	zieske	zieske	PROPN
dti-1334	656	2	,	,	PUNCT
dti-1334	656	3	l.r	l.r	PROPN
dti-1334	656	4	.	.	PROPN
dti-1334	656	5	2006	2006	NUM
dti-1334	656	6	.	.	PUNCT
dti-1334	657	1	a	a	DET
dti-1334	657	2	perspective	perspective	NOUN
dti-1334	657	3	on	on	ADP
dti-1334	657	4	the	the	DET
dti-1334	657	5	use	use	NOUN
dti-1334	657	6	of	of	ADP
dti-1334	657	7	itraq	itraq	PROPN
dti-1334	657	8	.	.	PUNCT
dti-1334	658	1	reagent	reagent	ADJ
dti-1334	658	2	technology	technology	NOUN
dti-1334	658	3	for	for	ADP
dti-1334	658	4	protein	protein	NOUN
dti-1334	658	5	complex	complex	ADJ
dti-1334	658	6	and	and	CCONJ
dti-1334	658	7	profi	profi	PROPN
dti-1334	658	8	ling	ling	PROPN
dti-1334	658	9	studies	study	NOUN
dti-1334	658	10	.	.	PUNCT
dti-1334	659	1	j.	j.	PROPN
dti-1334	659	2	exp	exp	PROPN
dti-1334	659	3	.	.	PUNCT
dti-1334	659	4	bot	bot	PROPN
dti-1334	659	5	.	.	PUNCT
dti-1334	659	6	,	,	PUNCT
dti-1334	659	7	57:1501–8	57:1501–8	NUM
dti-1334	659	8	.	.	PUNCT
dti-1334	660	1	<	<	X
dti-1334	660	2	<	<	X
dti-1334	660	3	/ascii85encodepages	/ascii85encodepage	NOUN
dti-1334	660	4	false	false	ADJ
dti-1334	660	5	/allowtransparency	/allowtransparency	NOUN
dti-1334	660	6	false	false	ADJ
dti-1334	660	7	/autopositionepsfiles	/autopositionepsfile	NOUN
dti-1334	660	8	true	true	ADJ
dti-1334	660	9	/autorotatepages	/autorotatepage	NOUN
dti-1334	660	10	/none	/none	PUNCT
dti-1334	660	11	/binding	/binding	PUNCT
dti-1334	660	12	/left	/left	ADJ
dti-1334	661	1	/calgrayprofile	/calgrayprofile	VERB
dti-1334	661	2	(	(	PUNCT
dti-1334	661	3	dot	dot	NOUN
dti-1334	661	4	gain	gain	NOUN
dti-1334	661	5	20	20	NUM
dti-1334	661	6	%	%	NOUN
dti-1334	661	7	)	)	PUNCT
dti-1334	661	8	/calrgbprofile	/calrgbprofile	PUNCT
dti-1334	662	1	(	(	PUNCT
dti-1334	662	2	srgb	srgb	PROPN
dti-1334	662	3	iec61966	iec61966	NOUN
dti-1334	662	4	-	-	PUNCT
dti-1334	662	5	2.1	2.1	NUM
dti-1334	662	6	)	)	PUNCT
dti-1334	662	7	/calcmykprofile	/calcmykprofile	PUNCT
dti-1334	663	1	(	(	PUNCT
dti-1334	663	2	u.s	u.s	PROPN
dti-1334	663	3	.	.	PROPN
dti-1334	663	4	web	web	NOUN
dti-1334	663	5	coated	coat	VERB
dti-1334	663	6	\050swop\051	\050swop\051	ADJ
dti-1334	663	7	v2	v2	NOUN
dti-1334	663	8	)	)	PUNCT
dti-1334	663	9	/srgbprofile	/srgbprofile	PUNCT
dti-1334	663	10	(	(	PUNCT
dti-1334	663	11	srgb	srgb	PROPN
dti-1334	663	12	iec61966	iec61966	NOUN
dti-1334	663	13	-	-	PUNCT
dti-1334	663	14	2.1	2.1	NUM
dti-1334	663	15	)	)	PUNCT
dti-1334	663	16	/cannotembedfontpolicy	/cannotembedfontpolicy	PUNCT
dti-1334	664	1	/error	/error	INTJ
dti-1334	664	2	/compatibilitylevel	/compatibilitylevel	NOUN
dti-1334	665	1	1.4	1.4	NUM
dti-1334	665	2	/compressobjects	/compressobject	NOUN
dti-1334	665	3	/tags	/tag	VERB
dti-1334	665	4	/compresspages	/compresspage	NOUN
dti-1334	665	5	true	true	ADJ
dti-1334	665	6	/convertimagestoindexed	/convertimagestoindexed	ADJ
dti-1334	665	7	true	true	ADJ
dti-1334	665	8	/passthroughjpegimages	/passthroughjpegimage	NOUN
dti-1334	665	9	true	true	ADJ
dti-1334	665	10	/createjdffile	/createjdffile	ADJ
dti-1334	665	11	false	false	ADJ
dti-1334	665	12	/createjobticket	/createjobticket	NOUN
dti-1334	665	13	false	false	ADJ
dti-1334	665	14	/defaultrenderingintent	/defaultrenderingintent	NOUN
dti-1334	665	15	/default	/default	PUNCT
dti-1334	665	16	/detectblends	/detectblend	NOUN
dti-1334	665	17	true	true	ADJ
dti-1334	665	18	/colorconversionstrategy	/colorconversionstrategy	NOUN
dti-1334	665	19	/leavecolorunchanged	/leavecolorunchange	VERB
dti-1334	665	20	/dothumbnails	/dothumbnail	VERB
dti-1334	665	21	false	false	ADJ
dti-1334	665	22	/embedallfonts	/embedallfont	NOUN
dti-1334	665	23	true	true	ADJ
dti-1334	665	24	/embedjoboptions	/embedjoboption	NOUN
dti-1334	665	25	true	true	ADJ
dti-1334	665	26	/dscreportinglevel	/dscreportinglevel	NOUN
dti-1334	665	27	0	0	NUM
dti-1334	665	28	/emitdscwarnings	/emitdscwarning	NOUN
dti-1334	665	29	false	false	ADJ
dti-1334	665	30	/endpage	/endpage	NOUN
dti-1334	665	31	-1	-1	NOUN
dti-1334	665	32	/imagememory	/imagememory	NUM
dti-1334	666	1	1048576	1048576	NUM
dti-1334	666	2	/lockdistillerparams	/lockdistillerparams	NOUN
dti-1334	666	3	false	false	ADJ
dti-1334	666	4	/maxsubsetpct	/maxsubsetpct	ADJ
dti-1334	666	5	100	100	NUM
dti-1334	666	6	/optimize	/optimize	NOUN
dti-1334	666	7	true	true	ADJ
dti-1334	666	8	/opm	/opm	NOUN
dti-1334	666	9	1	1	NUM
dti-1334	666	10	/parsedsccomments	/parsedsccomment	NOUN
dti-1334	666	11	true	true	ADJ
dti-1334	666	12	/parsedsccommentsfordocinfo	/parsedsccommentsfordocinfo	VERB
dti-1334	666	13	true	true	ADJ
dti-1334	666	14	/preservecopypage	/preservecopypage	NOUN
dti-1334	666	15	true	true	ADJ
dti-1334	666	16	/preserveepsinfo	/preserveepsinfo	NOUN
dti-1334	666	17	true	true	ADJ
dti-1334	666	18	/preservehalftoneinfo	/preservehalftoneinfo	PUNCT
dti-1334	666	19	false	false	ADJ
dti-1334	666	20	/preserveopicomments	/preserveopicomment	NOUN
dti-1334	666	21	false	false	ADJ
dti-1334	666	22	/preserveoverprintsettings	/preserveoverprintsetting	NOUN
dti-1334	666	23	true	true	ADJ
dti-1334	666	24	/startpage	/startpage	NOUN
dti-1334	666	25	1	1	NUM
dti-1334	666	26	/subsetfonts	/subsetfont	NOUN
dti-1334	666	27	true	true	ADJ
dti-1334	666	28	/transferfunctioninfo	/transferfunctioninfo	PUNCT
dti-1334	666	29	/apply	/apply	PUNCT
dti-1334	666	30	/ucrandbginfo	/ucrandbginfo	PUNCT
dti-1334	667	1	/preserve	/preserve	NOUN
dti-1334	667	2	/useprologue	/useprologue	NOUN
dti-1334	667	3	false	false	ADJ
dti-1334	667	4	/colorsettingsfile	/colorsettingsfile	NOUN
dti-1334	667	5	(	(	PUNCT
dti-1334	667	6	)	)	PUNCT
dti-1334	667	7	/alwaysembed	/alwaysembe	VERB
dti-1334	667	8	[	[	PUNCT
dti-1334	667	9	true	true	ADJ
dti-1334	667	10	]	]	PUNCT
dti-1334	667	11	/neverembed	/neverembed	PUNCT
dti-1334	668	1	[	[	PUNCT
dti-1334	668	2	true	true	ADJ
dti-1334	668	3	]	]	PUNCT
dti-1334	668	4	/antialiascolorimages	/antialiascolorimages	X
dti-1334	668	5	false	false	ADJ
dti-1334	668	6	/downsamplecolorimages	/downsamplecolorimage	NOUN
dti-1334	668	7	true	true	ADJ
dti-1334	668	8	/colorimagedownsampletype	/colorimagedownsampletype	PUNCT
dti-1334	668	9	/bicubic	/bicubic	NOUN
dti-1334	668	10	/colorimageresolution	/colorimageresolution	NOUN
dti-1334	668	11	300	300	NUM
dti-1334	668	12	/colorimagedepth	/colorimagedepth	PRON
dti-1334	669	1	-1	-1	INTJ
dti-1334	669	2	/colorimagedownsamplethreshold	/colorimagedownsamplethreshold	PUNCT
dti-1334	669	3	1.50000	1.50000	NUM
dti-1334	669	4	/encodecolorimages	/encodecolorimage	NOUN
dti-1334	669	5	true	true	ADJ
dti-1334	669	6	/colorimagefilter	/colorimagefilter	PUNCT
dti-1334	669	7	/dctencode	/dctencode	PUNCT
dti-1334	669	8	/autofiltercolorimages	/autofiltercolorimage	NOUN
dti-1334	669	9	true	true	ADJ
dti-1334	669	10	/colorimageautofilterstrategy	/colorimageautofilterstrategy	PUNCT
dti-1334	669	11	/jpeg	/jpeg	PUNCT
dti-1334	669	12	/coloracsimagedict	/coloracsimagedict	PUNCT
dti-1334	670	1	<	<	X
dti-1334	670	2	<	<	X
dti-1334	670	3	/qfactor	/qfactor	NOUN
dti-1334	670	4	0.15	0.15	NUM
dti-1334	670	5	/hsamples	/hsample	NOUN
dti-1334	671	1	[	[	X
dti-1334	671	2	1	1	NUM
dti-1334	671	3	1	1	NUM
dti-1334	671	4	1	1	NUM
dti-1334	671	5	1	1	NUM
dti-1334	671	6	]	]	PUNCT
dti-1334	671	7	/vsamples	/vsample	NOUN
dti-1334	672	1	[	[	X
dti-1334	672	2	1	1	NUM
dti-1334	672	3	1	1	NUM
dti-1334	672	4	1	1	NUM
dti-1334	672	5	1	1	NUM
dti-1334	672	6	]	]	PUNCT
dti-1334	672	7	>	>	PUNCT
dti-1334	672	8	>	>	X
dti-1334	672	9	/colorimagedict	/colorimagedict	PUNCT
dti-1334	673	1	<	<	X
dti-1334	673	2	<	<	X
dti-1334	673	3	/qfactor	/qfactor	NOUN
dti-1334	673	4	0.15	0.15	NUM
dti-1334	673	5	/hsamples	/hsample	NOUN
dti-1334	674	1	[	[	X
dti-1334	674	2	1	1	NUM
dti-1334	674	3	1	1	NUM
dti-1334	674	4	1	1	NUM
dti-1334	674	5	1	1	NUM
dti-1334	674	6	]	]	PUNCT
dti-1334	674	7	/vsamples	/vsample	NOUN
dti-1334	675	1	[	[	X
dti-1334	675	2	1	1	NUM
dti-1334	675	3	1	1	NUM
dti-1334	675	4	1	1	NUM
dti-1334	675	5	1	1	NUM
dti-1334	675	6	]	]	PUNCT
dti-1334	675	7	>	>	PUNCT
dti-1334	675	8	>	>	X
dti-1334	675	9	/jpeg2000coloracsimagedict	/jpeg2000coloracsimagedict	PUNCT
dti-1334	676	1	<	<	X
dti-1334	676	2	<	<	X
dti-1334	676	3	/tilewidth	/tilewidth	PUNCT
dti-1334	676	4	256	256	NUM
dti-1334	676	5	/tileheight	/tileheight	NUM
dti-1334	676	6	256	256	NUM
dti-1334	676	7	/quality	/quality	NOUN
dti-1334	676	8	30	30	NUM
dti-1334	676	9	>	>	PUNCT
dti-1334	676	10	>	>	X
dti-1334	676	11	/jpeg2000colorimagedict	/jpeg2000colorimagedict	PUNCT
dti-1334	676	12	<	<	X
dti-1334	676	13	<	<	X
dti-1334	676	14	/tilewidth	/tilewidth	PUNCT
dti-1334	676	15	256	256	NUM
dti-1334	676	16	/tileheight	/tileheight	NUM
dti-1334	676	17	256	256	NUM
dti-1334	676	18	/quality	/quality	NOUN
dti-1334	676	19	30	30	NUM
dti-1334	676	20	>	>	PUNCT
dti-1334	676	21	>	>	X
dti-1334	676	22	/antialiasgrayimages	/antialiasgrayimages	X
dti-1334	676	23	false	false	ADJ
dti-1334	676	24	/downsamplegrayimages	/downsamplegrayimage	NOUN
dti-1334	677	1	true	true	ADJ
dti-1334	677	2	/grayimagedownsampletype	/grayimagedownsampletype	NOUN
dti-1334	677	3	/bicubic	/bicubic	NOUN
dti-1334	677	4	/grayimageresolution	/grayimageresolution	NOUN
dti-1334	677	5	300	300	NUM
dti-1334	677	6	/grayimagedepth	/grayimagedepth	PUNCT
dti-1334	677	7	-1	-1	PUNCT
dti-1334	677	8	/grayimagedownsamplethreshold	/grayimagedownsamplethreshold	PRON
dti-1334	678	1	1.50000	1.50000	NUM
dti-1334	678	2	/encodegrayimages	/encodegrayimage	NOUN
dti-1334	678	3	true	true	ADJ
dti-1334	678	4	/grayimagefilter	/grayimagefilter	NOUN
dti-1334	678	5	/dctencode	/dctencode	PUNCT
dti-1334	679	1	/autofiltergrayimages	/autofiltergrayimages	VERB
dti-1334	679	2	true	true	ADJ
dti-1334	679	3	/grayimageautofilterstrategy	/grayimageautofilterstrategy	INTJ
dti-1334	679	4	/jpeg	/jpeg	PUNCT
dti-1334	679	5	/grayacsimagedict	/grayacsimagedict	PUNCT
dti-1334	680	1	<	<	X
dti-1334	680	2	<	<	X
dti-1334	680	3	/qfactor	/qfactor	NOUN
dti-1334	680	4	0.15	0.15	NUM
dti-1334	680	5	/hsamples	/hsample	NOUN
dti-1334	681	1	[	[	X
dti-1334	681	2	1	1	NUM
dti-1334	681	3	1	1	NUM
dti-1334	681	4	1	1	NUM
dti-1334	681	5	1	1	NUM
dti-1334	681	6	]	]	PUNCT
dti-1334	681	7	/vsamples	/vsample	NOUN
dti-1334	682	1	[	[	X
dti-1334	682	2	1	1	NUM
dti-1334	682	3	1	1	NUM
dti-1334	682	4	1	1	NUM
dti-1334	682	5	1	1	NUM
dti-1334	682	6	]	]	PUNCT
dti-1334	682	7	>	>	PUNCT
dti-1334	682	8	>	>	X
dti-1334	682	9	/grayimagedict	/grayimagedict	PUNCT
dti-1334	683	1	<	<	X
dti-1334	683	2	<	<	X
dti-1334	683	3	/qfactor	/qfactor	NOUN
dti-1334	683	4	0.15	0.15	NUM
dti-1334	683	5	/hsamples	/hsample	NOUN
dti-1334	684	1	[	[	X
dti-1334	684	2	1	1	NUM
dti-1334	684	3	1	1	NUM
dti-1334	684	4	1	1	NUM
dti-1334	684	5	1	1	NUM
dti-1334	684	6	]	]	PUNCT
dti-1334	684	7	/vsamples	/vsample	NOUN
dti-1334	685	1	[	[	X
dti-1334	685	2	1	1	NUM
dti-1334	685	3	1	1	NUM
dti-1334	685	4	1	1	NUM
dti-1334	685	5	1	1	NUM
dti-1334	685	6	]	]	PUNCT
dti-1334	685	7	>	>	X
dti-1334	685	8	>	>	X
dti-1334	685	9	/jpeg2000grayacsimagedict	/jpeg2000grayacsimagedict	PUNCT
dti-1334	686	1	<	<	X
dti-1334	686	2	<	<	X
dti-1334	686	3	/tilewidth	/tilewidth	PUNCT
dti-1334	686	4	256	256	NUM
dti-1334	686	5	/tileheight	/tileheight	NUM
dti-1334	686	6	256	256	NUM
dti-1334	686	7	/quality	/quality	NOUN
dti-1334	686	8	30	30	NUM
dti-1334	686	9	>	>	PUNCT
dti-1334	686	10	>	>	X
dti-1334	686	11	/jpeg2000grayimagedict	/jpeg2000grayimagedict	PUNCT
dti-1334	686	12	<	<	X
dti-1334	686	13	<	<	X
dti-1334	686	14	/tilewidth	/tilewidth	PUNCT
dti-1334	686	15	256	256	NUM
dti-1334	686	16	/tileheight	/tileheight	NUM
dti-1334	686	17	256	256	NUM
dti-1334	686	18	/quality	/quality	NOUN
dti-1334	686	19	30	30	NUM
dti-1334	686	20	>	>	PUNCT
dti-1334	686	21	>	>	X
dti-1334	686	22	/antialiasmonoimages	/antialiasmonoimage	NOUN
dti-1334	686	23	false	false	ADJ
dti-1334	686	24	/downsamplemonoimages	/downsamplemonoimage	NOUN
dti-1334	686	25	true	true	ADJ
dti-1334	686	26	/monoimagedownsampletype	/monoimagedownsampletype	PUNCT
dti-1334	686	27	/bicubic	/bicubic	NOUN
dti-1334	686	28	/monoimageresolution	/monoimageresolution	NOUN
dti-1334	686	29	1200	1200	NUM
dti-1334	686	30	/monoimagedepth	/monoimagedepth	PRON
dti-1334	686	31	-1	-1	PUNCT
dti-1334	686	32	/monoimagedownsamplethreshold	/monoimagedownsamplethreshold	PUNCT
dti-1334	686	33	1.50000	1.50000	NUM
dti-1334	686	34	/encodemonoimages	/encodemonoimage	NOUN
dti-1334	686	35	true	true	ADJ
dti-1334	686	36	/monoimagefilter	/monoimagefilter	ADP
dti-1334	686	37	/ccittfaxencode	/ccittfaxencode	INTJ
dti-1334	686	38	/monoimagedict	/monoimagedict	PUNCT
dti-1334	687	1	<	<	X
dti-1334	687	2	<	<	X
dti-1334	687	3	/k	/k	PUNCT
dti-1334	687	4	-1	-1	INTJ
dti-1334	687	5	>	>	PUNCT
dti-1334	687	6	>	>	X
dti-1334	687	7	/allowpsxobjects	/allowpsxobject	NOUN
dti-1334	688	1	false	false	ADJ
dti-1334	688	2	/pdfx1acheck	/pdfx1acheck	X
dti-1334	688	3	false	false	ADJ
dti-1334	688	4	/pdfx3check	/pdfx3check	PUNCT
dti-1334	688	5	false	false	ADJ
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dti-1334	700	8	/sve	/sve	NOUN
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dti-1334	701	4	/enu	/enu	PROPN
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dti-1334	701	11	>	>	X
dti-1334	701	12	setdistillerparams	setdistillerparam	NOUN
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dti-1334	702	3	/hwresolution	/hwresolution	NOUN
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dti-1334	704	6	>	>	X
dti-1334	704	7	setpagedevice	setpagedevice	PROPN