id	sid	tid	token	lemma	pos
dti-1338	1	1	drug	drug	NOUN
dti-1338	1	2	target	target	NOUN
dti-1338	1	3	insights	insight	NOUN
dti-1338	1	4	2011:5	2011:5	NUM
dti-1338	1	5	1–9	1–9	NUM
dti-1338	1	6	doi	doi	NOUN
dti-1338	1	7	:	:	PUNCT
dti-1338	1	8	10.4137	10.4137	NUM
dti-1338	1	9	/	/	SYM
dti-1338	1	10	dti.s6534	dti.s6534	NOUN
dti-1338	1	11	this	this	DET
dti-1338	1	12	article	article	NOUN
dti-1338	1	13	is	be	AUX
dti-1338	1	14	available	available	ADJ
dti-1338	1	15	from	from	ADP
dti-1338	1	16	http://www.la-press.com	http://www.la-press.com	X
dti-1338	1	17	.	.	PUNCT
dti-1338	2	1	©	©	ADP
dti-1338	2	2	the	the	DET
dti-1338	2	3	author(s	author(s	PROPN
dti-1338	2	4	)	)	PUNCT
dti-1338	2	5	,	,	PUNCT
dti-1338	2	6	publisher	publisher	NOUN
dti-1338	2	7	and	and	CCONJ
dti-1338	2	8	licensee	licensee	PROPN
dti-1338	2	9	libertas	libertas	PROPN
dti-1338	2	10	academica	academica	PROPN
dti-1338	2	11	ltd	ltd	PROPN
dti-1338	2	12	.	.	PUNCT
dti-1338	3	1	this	this	PRON
dti-1338	3	2	is	be	AUX
dti-1338	3	3	an	an	DET
dti-1338	3	4	open	open	ADJ
dti-1338	3	5	access	access	NOUN
dti-1338	3	6	article	article	NOUN
dti-1338	3	7	.	.	PUNCT
dti-1338	4	1	unrestricted	unrestricted	ADJ
dti-1338	4	2	non	non	ADJ
dti-1338	4	3	-	-	ADJ
dti-1338	4	4	commercial	commercial	ADJ
dti-1338	4	5	use	use	NOUN
dti-1338	4	6	is	be	AUX
dti-1338	4	7	permitted	permit	VERB
dti-1338	4	8	provided	provide	VERB
dti-1338	4	9	the	the	DET
dti-1338	4	10	original	original	ADJ
dti-1338	4	11	work	work	NOUN
dti-1338	4	12	is	be	AUX
dti-1338	4	13	properly	properly	ADV
dti-1338	4	14	cited	cite	VERB
dti-1338	4	15	.	.	PUNCT
dti-1338	5	1	open	open	ADJ
dti-1338	5	2	access	access	NOUN
dti-1338	5	3	full	full	ADJ
dti-1338	5	4	open	open	ADJ
dti-1338	5	5	access	access	NOUN
dti-1338	5	6	to	to	ADP
dti-1338	5	7	this	this	PRON
dti-1338	5	8	and	and	CCONJ
dti-1338	5	9	thousands	thousand	NOUN
dti-1338	5	10	of	of	ADP
dti-1338	5	11	other	other	ADJ
dti-1338	5	12	papers	paper	NOUN
dti-1338	5	13	at	at	ADP
dti-1338	5	14	http://www.la-press.com	http://www.la-press.com	X
dti-1338	5	15	.	.	PUNCT
dti-1338	6	1	drug	drug	NOUN
dti-1338	6	2	target	target	NOUN
dti-1338	6	3	insights	insight	NOUN
dti-1338	6	4	o	o	NOUN
dti-1338	6	5	r	r	NOUN
dti-1338	7	1	i	i	PRON
dti-1338	7	2	g	g	VERB
dti-1338	8	1	i	i	PRON
dti-1338	8	2	n	n	CCONJ
dti-1338	8	3	a	a	DET
dti-1338	8	4	l	l	NOUN
dti-1338	8	5	r	r	NOUN
dti-1338	8	6	e	e	NOUN
dti-1338	8	7	s	s	X
dti-1338	8	8	e	e	X
dti-1338	8	9	a	a	DET
dti-1338	8	10	r	r	NOUN
dti-1338	8	11	c	c	NOUN
dti-1338	8	12	h	h	NOUN
dti-1338	8	13	drug	drug	NOUN
dti-1338	8	14	target	target	NOUN
dti-1338	8	15	insights	insight	NOUN
dti-1338	8	16	2011:5	2011:5	NUM
dti-1338	8	17	1	1	NUM
dti-1338	8	18	the	the	DET
dti-1338	8	19	effect	effect	NOUN
dti-1338	8	20	of	of	ADP
dti-1338	8	21	valproic	valproic	ADJ
dti-1338	8	22	acid	acid	NOUN
dti-1338	8	23	on	on	ADP
dti-1338	8	24	mesenchymal	mesenchymal	ADJ
dti-1338	8	25	pluripotent	pluripotent	NOUN
dti-1338	8	26	cell	cell	NOUN
dti-1338	8	27	proliferation	proliferation	NOUN
dti-1338	8	28	and	and	CCONJ
dti-1338	8	29	differentiation	differentiation	NOUN
dti-1338	8	30	in	in	ADP
dti-1338	8	31	extracellular	extracellular	ADJ
dti-1338	8	32	matrices	matrix	NOUN
dti-1338	8	33	yuji	yuji	PROPN
dti-1338	8	34	hatakeyama1	hatakeyama1	PROPN
dti-1338	8	35	,	,	PUNCT
dti-1338	8	36	junko	junko	PROPN
dti-1338	8	37	hatakeyama1	hatakeyama1	PROPN
dti-1338	8	38	,	,	PUNCT
dti-1338	8	39	atsushi	atsushi	PROPN
dti-1338	8	40	takahashi2	takahashi2	PROPN
dti-1338	8	41	,	,	PUNCT
dti-1338	8	42	kyoko	kyoko	PROPN
dti-1338	8	43	oka1	oka1	PROPN
dti-1338	8	44	,	,	PUNCT
dti-1338	8	45	eichi	eichi	PROPN
dti-1338	8	46	tsuruga1	tsuruga1	PROPN
dti-1338	8	47	,	,	PUNCT
dti-1338	8	48	tetsuichiro	tetsuichiro	NOUN
dti-1338	8	49	inai1	inai1	NOUN
dti-1338	9	1	and	and	CCONJ
dti-1338	9	2	yoshihiko	yoshihiko	NOUN
dti-1338	9	3	sawa1	sawa1	NOUN
dti-1338	9	4	1department	1department	NUM
dti-1338	9	5	of	of	ADP
dti-1338	9	6	morphological	morphological	ADJ
dti-1338	9	7	biology	biology	NOUN
dti-1338	9	8	,	,	PUNCT
dti-1338	9	9	fukuoka	fukuoka	VERB
dti-1338	9	10	dental	dental	ADJ
dti-1338	9	11	college	college	NOUN
dti-1338	9	12	,	,	PUNCT
dti-1338	9	13	2	2	NUM
dti-1338	9	14	-	-	SYM
dti-1338	9	15	15	15	NUM
dti-1338	9	16	-	-	SYM
dti-1338	9	17	1	1	NUM
dti-1338	9	18	tamura	tamura	ADJ
dti-1338	9	19	,	,	PUNCT
dti-1338	9	20	sawara	sawara	NOUN
dti-1338	9	21	-	-	PUNCT
dti-1338	9	22	ku	ku	NOUN
dti-1338	9	23	,	,	PUNCT
dti-1338	9	24	fukuoka	fukuoka	VERB
dti-1338	9	25	814	814	NUM
dti-1338	9	26	-	-	SYM
dti-1338	9	27	0193	0193	NUM
dti-1338	9	28	,	,	PUNCT
dti-1338	9	29	japan	japan	PROPN
dti-1338	9	30	.	.	PUNCT
dti-1338	10	1	2division	2division	NUM
dti-1338	10	2	of	of	ADP
dti-1338	10	3	disabled	disabled	ADJ
dti-1338	10	4	dentistry	dentistry	NOUN
dti-1338	10	5	,	,	PUNCT
dti-1338	10	6	tohoku	tohoku	PROPN
dti-1338	10	7	university	university	NOUN
dti-1338	10	8	,	,	PUNCT
dti-1338	10	9	graduate	graduate	NOUN
dti-1338	10	10	school	school	NOUN
dti-1338	10	11	of	of	ADP
dti-1338	10	12	dentistry	dentistry	NOUN
dti-1338	10	13	,	,	PUNCT
dti-1338	10	14	4	4	NUM
dti-1338	10	15	-	-	SYM
dti-1338	10	16	1	1	NUM
dti-1338	10	17	,	,	PUNCT
dti-1338	10	18	seiryo	seiryo	NOUN
dti-1338	10	19	-	-	PUNCT
dti-1338	10	20	machi	machi	NOUN
dti-1338	10	21	,	,	PUNCT
dti-1338	10	22	aoba	aoba	PROPN
dti-1338	10	23	-	-	PUNCT
dti-1338	10	24	ku	ku	PROPN
dti-1338	10	25	,	,	PUNCT
dti-1338	10	26	sendai	sendai	PROPN
dti-1338	10	27	980	980	NUM
dti-1338	10	28	-	-	PUNCT
dti-1338	10	29	8575	8575	NUM
dti-1338	10	30	,	,	PUNCT
dti-1338	10	31	japan	japan	PROPN
dti-1338	10	32	.	.	PUNCT
dti-1338	11	1	corresponding	correspond	VERB
dti-1338	11	2	author	author	NOUN
dti-1338	11	3	email	email	NOUN
dti-1338	11	4	:	:	PUNCT
dti-1338	11	5	yuji_hatakey@hotmail.com	yuji_hatakey@hotmail.com	X
dti-1338	11	6	abstract	abstract	NOUN
dti-1338	11	7	:	:	PUNCT
dti-1338	11	8	valproic	valproic	ADJ
dti-1338	11	9	acid	acid	NOUN
dti-1338	11	10	(	(	PUNCT
dti-1338	11	11	2	2	NUM
dti-1338	11	12	-	-	PUNCT
dti-1338	11	13	n	n	CCONJ
dti-1338	11	14	-	-	PUNCT
dti-1338	11	15	propylpentanoic	propylpentanoic	VERB
dti-1338	11	16	acid	acid	NOUN
dti-1338	11	17	,	,	PUNCT
dti-1338	11	18	vpa	vpa	PROPN
dti-1338	11	19	)	)	PUNCT
dti-1338	11	20	is	be	AUX
dti-1338	11	21	a	a	DET
dti-1338	11	22	widely	widely	ADV
dti-1338	11	23	used	use	VERB
dti-1338	11	24	antiepileptic	antiepileptic	ADJ
dti-1338	11	25	and	and	CCONJ
dti-1338	11	26	anticonvulsant	anticonvulsant	ADJ
dti-1338	11	27	drug	drug	NOUN
dti-1338	11	28	.	.	PUNCT
dti-1338	12	1	previous	previous	ADJ
dti-1338	12	2	studies	study	NOUN
dti-1338	12	3	have	have	AUX
dti-1338	12	4	reported	report	VERB
dti-1338	12	5	that	that	SCONJ
dti-1338	12	6	vpa	vpa	PROPN
dti-1338	12	7	effects	effect	NOUN
dti-1338	12	8	osteogenesis	osteogenesis	VERB
dti-1338	12	9	in	in	ADP
dti-1338	12	10	vivo	vivo	NOUN
dti-1338	12	11	and	and	CCONJ
dti-1338	12	12	in	in	ADP
dti-1338	12	13	vitro	vitro	X
dti-1338	12	14	,	,	PUNCT
dti-1338	12	15	yet	yet	CCONJ
dti-1338	12	16	it	it	PRON
dti-1338	12	17	remains	remain	VERB
dti-1338	12	18	unclear	unclear	ADJ
dti-1338	12	19	whether	whether	SCONJ
dti-1338	12	20	vpa	vpa	PROPN
dti-1338	12	21	promotes	promote	VERB
dti-1338	12	22	cell	cell	NOUN
dti-1338	12	23	differentiation	differentiation	NOUN
dti-1338	12	24	of	of	ADP
dti-1338	12	25	osteoblasts	osteoblast	NOUN
dti-1338	12	26	derived	derive	VERB
dti-1338	12	27	from	from	ADP
dti-1338	12	28	mesenchymal	mesenchymal	ADJ
dti-1338	12	29	cells	cell	NOUN
dti-1338	12	30	.	.	PUNCT
dti-1338	13	1	the	the	DET
dti-1338	13	2	purpose	purpose	NOUN
dti-1338	13	3	of	of	ADP
dti-1338	13	4	this	this	DET
dti-1338	13	5	study	study	NOUN
dti-1338	13	6	was	be	AUX
dti-1338	13	7	to	to	PART
dti-1338	13	8	clarify	clarify	VERB
dti-1338	13	9	the	the	DET
dti-1338	13	10	effect	effect	NOUN
dti-1338	13	11	of	of	ADP
dti-1338	13	12	vpa	vpa	PROPN
dti-1338	13	13	on	on	ADP
dti-1338	13	14	undifferentiated	undifferentiated	ADJ
dti-1338	13	15	pluripotent	pluripotent	ADJ
dti-1338	13	16	mesenchymal	mesenchymal	NOUN
dti-1338	13	17	cell	cell	NOUN
dti-1338	13	18	proliferation	proliferation	NOUN
dti-1338	13	19	and	and	CCONJ
dti-1338	13	20	differentiation	differentiation	NOUN
dti-1338	13	21	into	into	ADP
dti-1338	13	22	osteoblasts	osteoblast	NOUN
dti-1338	13	23	while	while	SCONJ
dti-1338	13	24	analyzing	analyze	VERB
dti-1338	13	25	the	the	DET
dti-1338	13	26	impact	impact	NOUN
dti-1338	13	27	of	of	ADP
dti-1338	13	28	the	the	DET
dti-1338	13	29	absence	absence	NOUN
dti-1338	13	30	or	or	CCONJ
dti-1338	13	31	presence	presence	NOUN
dti-1338	13	32	of	of	ADP
dti-1338	13	33	extracellular	extracellular	ADJ
dti-1338	13	34	matrices	matrix	NOUN
dti-1338	13	35	(	(	PUNCT
dti-1338	13	36	ecms	ecms	NOUN
dti-1338	13	37	)	)	PUNCT
dti-1338	13	38	.	.	PUNCT
dti-1338	14	1	mouse	mouse	NOUN
dti-1338	14	2	mesenchymal	mesenchymal	ADJ
dti-1338	14	3	cells	cell	NOUN
dti-1338	14	4	were	be	AUX
dti-1338	14	5	cultured	cultured	ADJ
dti-1338	14	6	on	on	ADP
dti-1338	14	7	non	non	ADJ
dti-1338	14	8	-	-	ADJ
dti-1338	14	9	coated	coated	ADJ
dti-1338	14	10	plastic	plastic	NOUN
dti-1338	14	11	,	,	PUNCT
dti-1338	14	12	type	type	NOUN
dti-1338	14	13	i	i	PRON
dti-1338	14	14	collagen	collagen	NOUN
dti-1338	14	15	-	-	PUNCT
dti-1338	14	16	coated	coated	ADJ
dti-1338	14	17	,	,	PUNCT
dti-1338	14	18	and	and	CCONJ
dti-1338	14	19	fibronectin	fibronectin	NOUN
dti-1338	14	20	-	-	PUNCT
dti-1338	14	21	coated	coat	VERB
dti-1338	14	22	plates	plate	NOUN
dti-1338	14	23	in	in	ADP
dti-1338	14	24	the	the	DET
dti-1338	14	25	absence	absence	NOUN
dti-1338	14	26	or	or	CCONJ
dti-1338	14	27	presence	presence	NOUN
dti-1338	14	28	of	of	ADP
dti-1338	14	29	vpa	vpa	PROPN
dti-1338	14	30	.	.	PUNCT
dti-1338	15	1	a	a	DET
dti-1338	15	2	cell	cell	NOUN
dti-1338	15	3	proliferation	proliferation	NOUN
dti-1338	15	4	assay	assay	NOUN
dti-1338	15	5	was	be	AUX
dti-1338	15	6	performed	perform	VERB
dti-1338	15	7	in	in	ADP
dti-1338	15	8	which	which	PRON
dti-1338	15	9	modified	modify	VERB
dti-1338	15	10	formazan	formazan	ADJ
dti-1338	15	11	dye	dye	NOUN
dti-1338	15	12	content	content	NOUN
dti-1338	15	13	was	be	AUX
dti-1338	15	14	analyzed	analyze	VERB
dti-1338	15	15	and	and	CCONJ
dti-1338	15	16	proliferation	proliferation	NOUN
dti-1338	15	17	nuclear	nuclear	ADJ
dti-1338	15	18	antigen	antigen	NOUN
dti-1338	15	19	(	(	PUNCT
dti-1338	15	20	pcna)-positive	pcna)-positive	ADJ
dti-1338	15	21	cells	cell	NOUN
dti-1338	15	22	were	be	AUX
dti-1338	15	23	counted	count	VERB
dti-1338	15	24	at	at	ADP
dti-1338	15	25	various	various	ADJ
dti-1338	15	26	concentrations	concentration	NOUN
dti-1338	15	27	of	of	ADP
dti-1338	15	28	vpa	vpa	PROPN
dti-1338	15	29	.	.	PUNCT
dti-1338	16	1	a	a	DET
dti-1338	16	2	high	high	ADJ
dti-1338	16	3	concentration	concentration	NOUN
dti-1338	16	4	of	of	ADP
dti-1338	16	5	vpa	vpa	PROPN
dti-1338	16	6	did	do	AUX
dti-1338	16	7	not	not	PART
dti-1338	16	8	clearly	clearly	ADV
dti-1338	16	9	alter	alter	VERB
dti-1338	16	10	cell	cell	NOUN
dti-1338	16	11	morphology	morphology	NOUN
dti-1338	16	12	,	,	PUNCT
dti-1338	16	13	but	but	CCONJ
dti-1338	16	14	large	large	ADJ
dti-1338	16	15	numbers	number	NOUN
dti-1338	16	16	of	of	ADP
dti-1338	16	17	stress	stress	NOUN
dti-1338	16	18	fibers	fiber	NOUN
dti-1338	16	19	were	be	AUX
dti-1338	16	20	observed	observe	VERB
dti-1338	16	21	in	in	ADP
dti-1338	16	22	these	these	DET
dti-1338	16	23	cells	cell	NOUN
dti-1338	16	24	and	and	CCONJ
dti-1338	16	25	the	the	DET
dti-1338	16	26	cell	cell	NOUN
dti-1338	16	27	proliferation	proliferation	NOUN
dti-1338	16	28	ratio	ratio	NOUN
dti-1338	16	29	was	be	AUX
dti-1338	16	30	decreased	decrease	VERB
dti-1338	16	31	with	with	ADP
dti-1338	16	32	positive	positive	ADJ
dti-1338	16	33	pcna	pcna	NOUN
dti-1338	16	34	counts	count	NOUN
dti-1338	16	35	.	.	PUNCT
dti-1338	17	1	in	in	ADP
dti-1338	17	2	the	the	DET
dti-1338	17	3	presence	presence	NOUN
dti-1338	17	4	of	of	ADP
dti-1338	17	5	matrices	matrix	NOUN
dti-1338	17	6	,	,	PUNCT
dti-1338	17	7	the	the	DET
dti-1338	17	8	cell	cell	NOUN
dti-1338	17	9	proliferation	proliferation	NOUN
dti-1338	17	10	ratio	ratio	NOUN
dti-1338	17	11	decreased	decrease	VERB
dti-1338	17	12	at	at	ADP
dti-1338	17	13	low	low	ADJ
dti-1338	17	14	vpa	vpa	PROPN
dti-1338	17	15	concentrations	concentration	NOUN
dti-1338	17	16	compared	compare	VERB
dti-1338	17	17	with	with	ADP
dti-1338	17	18	the	the	DET
dti-1338	17	19	ratio	ratio	NOUN
dti-1338	17	20	obtained	obtain	VERB
dti-1338	17	21	in	in	ADP
dti-1338	17	22	the	the	DET
dti-1338	17	23	absence	absence	NOUN
dti-1338	17	24	of	of	ADP
dti-1338	17	25	these	these	DET
dti-1338	17	26	ecms	ecms	NOUN
dti-1338	17	27	.	.	PUNCT
dti-1338	18	1	on	on	ADP
dti-1338	18	2	the	the	DET
dti-1338	18	3	other	other	ADJ
dti-1338	18	4	hand	hand	NOUN
dti-1338	18	5	,	,	PUNCT
dti-1338	18	6	vpa	vpa	PROPN
dti-1338	18	7	promoted	promote	VERB
dti-1338	18	8	osteoblastic	osteoblastic	ADJ
dti-1338	18	9	differentiation	differentiation	NOUN
dti-1338	18	10	in	in	ADP
dti-1338	18	11	the	the	DET
dti-1338	18	12	presence	presence	NOUN
dti-1338	18	13	of	of	ADP
dti-1338	18	14	type	type	NOUN
dti-1338	18	15	i	i	PRON
dti-1338	18	16	collagen	collagen	VERB
dti-1338	18	17	.	.	PUNCT
dti-1338	19	1	these	these	DET
dti-1338	19	2	findings	finding	NOUN
dti-1338	19	3	indicate	indicate	VERB
dti-1338	19	4	that	that	SCONJ
dti-1338	19	5	for	for	ADP
dti-1338	19	6	undifferentiated	undifferentiated	ADJ
dti-1338	19	7	mesenchymal	mesenchymal	NOUN
dti-1338	19	8	cells	cell	NOUN
dti-1338	19	9	,	,	PUNCT
dti-1338	19	10	vpa	vpa	PROPN
dti-1338	19	11	promotes	promote	VERB
dti-1338	19	12	a	a	DET
dti-1338	19	13	decrease	decrease	NOUN
dti-1338	19	14	in	in	ADP
dti-1338	19	15	the	the	DET
dti-1338	19	16	cell	cell	NOUN
dti-1338	19	17	proliferation	proliferation	NOUN
dti-1338	19	18	rate	rate	NOUN
dti-1338	19	19	in	in	ADP
dti-1338	19	20	the	the	DET
dti-1338	19	21	presence	presence	NOUN
dti-1338	19	22	of	of	ADP
dti-1338	19	23	ecms	ecms	NOUN
dti-1338	19	24	and	and	CCONJ
dti-1338	19	25	promotes	promote	VERB
dti-1338	19	26	osteoblastic	osteoblastic	ADJ
dti-1338	19	27	differentiation	differentiation	NOUN
dti-1338	19	28	,	,	PUNCT
dti-1338	19	29	both	both	PRON
dti-1338	19	30	of	of	ADP
dti-1338	19	31	which	which	PRON
dti-1338	19	32	could	could	AUX
dti-1338	19	33	provide	provide	VERB
dti-1338	19	34	insight	insight	NOUN
dti-1338	19	35	into	into	ADP
dti-1338	19	36	additional	additional	ADJ
dti-1338	19	37	mechanisms	mechanism	NOUN
dti-1338	19	38	of	of	ADP
dti-1338	19	39	osteoblastic	osteoblastic	ADJ
dti-1338	19	40	cell	cell	NOUN
dti-1338	19	41	differentiation	differentiation	NOUN
dti-1338	19	42	caused	cause	VERB
dti-1338	19	43	by	by	ADP
dti-1338	19	44	vpa	vpa	PROPN
dti-1338	19	45	.	.	PUNCT
dti-1338	20	1	keywords	keyword	NOUN
dti-1338	20	2	:	:	PUNCT
dti-1338	20	3	mesenchymal	mesenchymal	ADJ
dti-1338	20	4	cells	cell	NOUN
dti-1338	20	5	,	,	PUNCT
dti-1338	20	6	valproic	valproic	ADJ
dti-1338	20	7	acid	acid	NOUN
dti-1338	20	8	,	,	PUNCT
dti-1338	20	9	cell	cell	NOUN
dti-1338	20	10	proliferation	proliferation	NOUN
dti-1338	20	11	http:/dx.doi.org/10.4137	http:/dx.doi.org/10.4137	NUM
dti-1338	20	12	/	/	SYM
dti-1338	20	13	dti.s6534	dti.s6534	PROPN
dti-1338	20	14	http://www.la-press.com	http://www.la-press.com	X
dti-1338	20	15	http://www.la-press.com	http://www.la-press.com	X
dti-1338	20	16	http://www.la-press.com/drug-target-insights-journal-j23	http://www.la-press.com/drug-target-insights-journal-j23	PROPN
dti-1338	20	17	http://www.la-press.com	http://www.la-press.com	X
dti-1338	20	18	mailto:yuji_hatakey@hotmail.com	mailto:yuji_hatakey@hotmail.com	X
dti-1338	20	19	hatakeyama	hatakeyama	PROPN
dti-1338	20	20	et	et	PROPN
dti-1338	20	21	al	al	PROPN
dti-1338	20	22	2	2	NUM
dti-1338	20	23	drug	drug	NOUN
dti-1338	20	24	target	target	NOUN
dti-1338	20	25	insights	insight	NOUN
dti-1338	20	26	2011:5	2011:5	NUM
dti-1338	20	27	introduction	introduction	NOUN
dti-1338	20	28	valproic	valproic	ADJ
dti-1338	20	29	acid	acid	NOUN
dti-1338	20	30	(	(	PUNCT
dti-1338	20	31	2	2	NUM
dti-1338	20	32	-	-	PUNCT
dti-1338	20	33	n	n	CCONJ
dti-1338	20	34	-	-	PUNCT
dti-1338	20	35	propylpentanoic	propylpentanoic	VERB
dti-1338	20	36	acid	acid	NOUN
dti-1338	20	37	,	,	PUNCT
dti-1338	20	38	vpa	vpa	PROPN
dti-1338	20	39	)	)	PUNCT
dti-1338	20	40	is	be	AUX
dti-1338	20	41	an	an	DET
dti-1338	20	42	effective	effective	ADJ
dti-1338	20	43	and	and	CCONJ
dti-1338	20	44	widely	widely	ADV
dti-1338	20	45	used	use	VERB
dti-1338	20	46	antiepileptic	antiepileptic	ADJ
dti-1338	20	47	and	and	CCONJ
dti-1338	20	48	anticonvulsant	anticonvulsant	ADJ
dti-1338	20	49	drug	drug	NOUN
dti-1338	20	50	,	,	PUNCT
dti-1338	20	51	and	and	CCONJ
dti-1338	20	52	recent	recent	ADJ
dti-1338	20	53	studies	study	NOUN
dti-1338	20	54	have	have	AUX
dti-1338	20	55	reported	report	VERB
dti-1338	20	56	that	that	SCONJ
dti-1338	20	57	vpa	vpa	PROPN
dti-1338	20	58	influences	influence	VERB
dti-1338	20	59	osteogenesis	osteogenesis	NOUN
dti-1338	20	60	in	in	ADP
dti-1338	20	61	vivo	vivo	NOUN
dti-1338	20	62	and	and	CCONJ
dti-1338	20	63	in	in	ADP
dti-1338	20	64	vitro.1–4	vitro.1–4	NOUN
dti-1338	20	65	it	it	PRON
dti-1338	20	66	has	have	AUX
dti-1338	20	67	been	be	AUX
dti-1338	20	68	reported	report	VERB
dti-1338	20	69	that	that	SCONJ
dti-1338	20	70	vpa	vpa	PROPN
dti-1338	20	71	has	have	VERB
dti-1338	20	72	no	no	DET
dti-1338	20	73	effect	effect	NOUN
dti-1338	20	74	on	on	ADP
dti-1338	20	75	osteogenesis	osteogenesis	NOUN
dti-1338	20	76	identified	identify	VERB
dti-1338	20	77	with	with	ADP
dti-1338	20	78	calcification	calcification	NOUN
dti-1338	20	79	nodule	nodule	NOUN
dti-1338	20	80	formation	formation	NOUN
dti-1338	20	81	by	by	ADP
dti-1338	20	82	a	a	DET
dti-1338	20	83	preosteoblast	preosteoblast	NOUN
dti-1338	20	84	cell	cell	NOUN
dti-1338	20	85	line	line	NOUN
dti-1338	20	86	derived	derive	VERB
dti-1338	20	87	from	from	ADP
dti-1338	20	88	mouse	mouse	NOUN
dti-1338	20	89	calvaria	calvaria	NOUN
dti-1338	20	90	,	,	PUNCT
dti-1338	20	91	mc3t3	mc3t3	NOUN
dti-1338	20	92	-	-	PUNCT
dti-1338	20	93	e1	e1	PROPN
dti-1338	20	94	cells.5	cells.5	NOUN
dti-1338	20	95	on	on	ADP
dti-1338	20	96	the	the	DET
dti-1338	20	97	other	other	ADJ
dti-1338	20	98	hand	hand	NOUN
dti-1338	20	99	,	,	PUNCT
dti-1338	20	100	vpa	vpa	PROPN
dti-1338	20	101	promotes	promote	VERB
dti-1338	20	102	the	the	DET
dti-1338	20	103	cell	cell	NOUN
dti-1338	20	104	proliferation	proliferation	NOUN
dti-1338	20	105	of	of	ADP
dti-1338	20	106	a	a	DET
dti-1338	20	107	pre	pre	ADJ
dti-1338	20	108	-	-	ADJ
dti-1338	20	109	osteoblast	osteoblast	ADJ
dti-1338	20	110	cell	cell	NOUN
dti-1338	20	111	line	line	NOUN
dti-1338	20	112	and	and	CCONJ
dti-1338	20	113	the	the	DET
dti-1338	20	114	runx2	runx2	NOUN
dti-1338	20	115	gene	gene	NOUN
dti-1338	20	116	,	,	PUNCT
dti-1338	20	117	which	which	PRON
dti-1338	20	118	plays	play	VERB
dti-1338	20	119	a	a	DET
dti-1338	20	120	critical	critical	ADJ
dti-1338	20	121	role	role	NOUN
dti-1338	20	122	in	in	ADP
dti-1338	20	123	osteoblast	osteoblast	ADJ
dti-1338	20	124	differentiation	differentiation	NOUN
dti-1338	20	125	,	,	PUNCT
dti-1338	20	126	with	with	SCONJ
dti-1338	20	127	transcriptional	transcriptional	ADJ
dti-1338	20	128	activity	activity	NOUN
dti-1338	20	129	promoted	promote	VERB
dti-1338	20	130	in	in	ADP
dti-1338	20	131	mc3t3	mc3t3	PROPN
dti-1338	20	132	-	-	PUNCT
dti-1338	20	133	e1.4	e1.4	NOUN
dti-1338	20	134	these	these	DET
dti-1338	20	135	findings	finding	NOUN
dti-1338	20	136	indicate	indicate	VERB
dti-1338	20	137	that	that	SCONJ
dti-1338	20	138	skeletal	skeletal	ADJ
dti-1338	20	139	malformation	malformation	NOUN
dti-1338	20	140	caused	cause	VERB
dti-1338	20	141	by	by	ADP
dti-1338	20	142	vpa	vpa	PROPN
dti-1338	20	143	may	may	AUX
dti-1338	20	144	result	result	VERB
dti-1338	20	145	in	in	ADP
dti-1338	20	146	response	response	NOUN
dti-1338	20	147	to	to	ADP
dti-1338	20	148	cell	cell	NOUN
dti-1338	20	149	proliferation	proliferation	NOUN
dti-1338	20	150	and/or	and/or	CCONJ
dti-1338	20	151	cellular	cellular	ADJ
dti-1338	20	152	differentiation	differentiation	NOUN
dti-1338	20	153	of	of	ADP
dti-1338	20	154	preosteoblasts	preosteoblast	NOUN
dti-1338	20	155	,	,	PUNCT
dti-1338	20	156	and	and	CCONJ
dti-1338	20	157	may	may	AUX
dti-1338	20	158	not	not	PART
dti-1338	20	159	result	result	VERB
dti-1338	20	160	in	in	ADP
dti-1338	20	161	calcification	calcification	NOUN
dti-1338	20	162	by	by	ADP
dti-1338	20	163	mature	mature	ADJ
dti-1338	20	164	osteoblasts	osteoblast	NOUN
dti-1338	20	165	.	.	PUNCT
dti-1338	21	1	bone	bone	NOUN
dti-1338	21	2	is	be	AUX
dti-1338	21	3	composed	compose	VERB
dti-1338	21	4	of	of	ADP
dti-1338	21	5	not	not	PART
dti-1338	21	6	only	only	ADV
dti-1338	21	7	osteoblasts	osteoblast	NOUN
dti-1338	21	8	and	and	CCONJ
dti-1338	21	9	osteocytes	osteocyte	NOUN
dti-1338	21	10	but	but	CCONJ
dti-1338	21	11	also	also	ADV
dti-1338	21	12	chondrocytes	chondrocyte	NOUN
dti-1338	21	13	and	and	CCONJ
dti-1338	21	14	adipocytes	adipocyte	NOUN
dti-1338	21	15	,	,	PUNCT
dti-1338	21	16	which	which	PRON
dti-1338	21	17	are	be	AUX
dti-1338	21	18	organized	organize	VERB
dti-1338	21	19	and	and	CCONJ
dti-1338	21	20	integrated	integrate	VERB
dti-1338	21	21	so	so	ADV
dti-1338	21	22	as	as	SCONJ
dti-1338	21	23	to	to	PART
dti-1338	21	24	maintain	maintain	VERB
dti-1338	21	25	bone	bone	NOUN
dti-1338	21	26	homeostasis	homeostasis	NOUN
dti-1338	21	27	.	.	PUNCT
dti-1338	22	1	these	these	DET
dti-1338	22	2	various	various	ADJ
dti-1338	22	3	types	type	NOUN
dti-1338	22	4	of	of	ADP
dti-1338	22	5	cells	cell	NOUN
dti-1338	22	6	are	be	AUX
dti-1338	22	7	all	all	PRON
dti-1338	22	8	derived	derive	VERB
dti-1338	22	9	from	from	ADP
dti-1338	22	10	mesenchymal	mesenchymal	ADJ
dti-1338	22	11	stem	stem	NOUN
dti-1338	22	12	cells	cell	NOUN
dti-1338	22	13	.	.	PUNCT
dti-1338	23	1	mouse	mouse	NOUN
dti-1338	23	2	embryonic	embryonic	ADJ
dti-1338	23	3	mesenchymal	mesenchymal	ADJ
dti-1338	23	4	cells	cell	NOUN
dti-1338	23	5	c3h10t1/2	c3h10t1/2	PRON
dti-1338	23	6	are	be	AUX
dti-1338	23	7	pluripotent	pluripotent	ADJ
dti-1338	23	8	cells	cell	NOUN
dti-1338	23	9	which	which	PRON
dti-1338	23	10	can	can	AUX
dti-1338	23	11	be	be	AUX
dti-1338	23	12	differentiated	differentiate	VERB
dti-1338	23	13	into	into	ADP
dti-1338	23	14	osteoblasts	osteoblast	NOUN
dti-1338	23	15	,	,	PUNCT
dti-1338	23	16	chondrocytes	chondrocyte	NOUN
dti-1338	23	17	,	,	PUNCT
dti-1338	23	18	adipocytes	adipocyte	NOUN
dti-1338	23	19	,	,	PUNCT
dti-1338	23	20	and	and	CCONJ
dti-1338	23	21	myoblasts	myoblast	NOUN
dti-1338	23	22	in	in	ADP
dti-1338	23	23	vitro.6–8	vitro.6–8	PROPN
dti-1338	23	24	this	this	DET
dti-1338	23	25	cell	cell	NOUN
dti-1338	23	26	line	line	NOUN
dti-1338	23	27	is	be	AUX
dti-1338	23	28	widely	widely	ADV
dti-1338	23	29	used	use	VERB
dti-1338	23	30	as	as	ADP
dti-1338	23	31	a	a	DET
dti-1338	23	32	model	model	NOUN
dti-1338	23	33	of	of	ADP
dti-1338	23	34	mesenchymal	mesenchymal	ADJ
dti-1338	23	35	cell	cell	NOUN
dti-1338	23	36	differentiation	differentiation	NOUN
dti-1338	23	37	as	as	SCONJ
dti-1338	23	38	it	it	PRON
dti-1338	23	39	represents	represent	VERB
dti-1338	23	40	a	a	DET
dti-1338	23	41	homogeneous	homogeneous	ADJ
dti-1338	23	42	population	population	NOUN
dti-1338	23	43	of	of	ADP
dti-1338	23	44	pluripotent	pluripotent	ADJ
dti-1338	23	45	cells	cell	NOUN
dti-1338	23	46	that	that	PRON
dti-1338	23	47	do	do	AUX
dti-1338	23	48	not	not	PART
dti-1338	23	49	spontaneously	spontaneously	ADV
dti-1338	23	50	differentiate	differentiate	VERB
dti-1338	23	51	under	under	ADP
dti-1338	23	52	normal	normal	ADJ
dti-1338	23	53	culture	culture	NOUN
dti-1338	23	54	conditions	condition	NOUN
dti-1338	23	55	.	.	PUNCT
dti-1338	24	1	extracellular	extracellular	ADJ
dti-1338	24	2	matrices	matrix	NOUN
dti-1338	24	3	(	(	PUNCT
dti-1338	24	4	ecms	ecms	NOUN
dti-1338	24	5	)	)	PUNCT
dti-1338	24	6	,	,	PUNCT
dti-1338	24	7	a	a	DET
dti-1338	24	8	complex	complex	ADJ
dti-1338	24	9	mixture	mixture	NOUN
dti-1338	24	10	of	of	ADP
dti-1338	24	11	matrix	matrix	NOUN
dti-1338	24	12	molecules	molecule	NOUN
dti-1338	24	13	,	,	PUNCT
dti-1338	24	14	including	include	VERB
dti-1338	24	15	collagen	collagen	NOUN
dti-1338	24	16	and	and	CCONJ
dti-1338	24	17	fibronectin	fibronectin	NOUN
dti-1338	24	18	,	,	PUNCT
dti-1338	24	19	provide	provide	VERB
dti-1338	24	20	scaffolds	scaffold	NOUN
dti-1338	24	21	for	for	ADP
dti-1338	24	22	cellular	cellular	ADJ
dti-1338	24	23	support	support	NOUN
dti-1338	24	24	that	that	PRON
dti-1338	24	25	are	be	AUX
dti-1338	24	26	present	present	ADJ
dti-1338	24	27	in	in	ADP
dti-1338	24	28	all	all	DET
dti-1338	24	29	tissues	tissue	NOUN
dti-1338	24	30	,	,	PUNCT
dti-1338	24	31	organs	organ	NOUN
dti-1338	24	32	,	,	PUNCT
dti-1338	24	33	and	and	CCONJ
dti-1338	24	34	cell	cell	NOUN
dti-1338	24	35	-	-	PUNCT
dti-1338	24	36	matrix	matrix	NOUN
dti-1338	24	37	adhesion	adhesion	NOUN
dti-1338	24	38	signals	signal	NOUN
dti-1338	24	39	,	,	PUNCT
dti-1338	24	40	and	and	CCONJ
dti-1338	24	41	regulate	regulate	VERB
dti-1338	24	42	biological	biological	ADJ
dti-1338	24	43	processes	process	NOUN
dti-1338	24	44	such	such	ADJ
dti-1338	24	45	as	as	ADP
dti-1338	24	46	cell	cell	NOUN
dti-1338	24	47	survival	survival	NOUN
dti-1338	24	48	and	and	CCONJ
dti-1338	24	49	proliferation.9	proliferation.9	PROPN
dti-1338	24	50	both	both	DET
dti-1338	24	51	type	type	NOUN
dti-1338	24	52	i	i	PRON
dti-1338	24	53	collagen	collagen	NOUN
dti-1338	24	54	and	and	CCONJ
dti-1338	24	55	fibronectin	fibronectin	NOUN
dti-1338	24	56	play	play	VERB
dti-1338	24	57	a	a	DET
dti-1338	24	58	critical	critical	ADJ
dti-1338	24	59	role	role	NOUN
dti-1338	24	60	in	in	ADP
dti-1338	24	61	osteogenic	osteogenic	ADJ
dti-1338	24	62	cell	cell	NOUN
dti-1338	24	63	proliferation	proliferation	NOUN
dti-1338	24	64	and	and	CCONJ
dti-1338	24	65	cell	cell	NOUN
dti-1338	24	66	differentiation	differentiation	NOUN
dti-1338	24	67	both	both	CCONJ
dti-1338	24	68	in	in	ADP
dti-1338	24	69	vivo	vivo	NOUN
dti-1338	24	70	and	and	CCONJ
dti-1338	24	71	in	in	ADP
dti-1338	24	72	vitro;10–13	vitro;10–13	NOUN
dti-1338	24	73	however	however	ADV
dti-1338	24	74	,	,	PUNCT
dti-1338	24	75	it	it	PRON
dti-1338	24	76	remains	remain	VERB
dti-1338	24	77	unclear	unclear	ADJ
dti-1338	24	78	what	what	PRON
dti-1338	24	79	the	the	DET
dti-1338	24	80	effect	effect	NOUN
dti-1338	24	81	of	of	ADP
dti-1338	24	82	vpa	vpa	PROPN
dti-1338	24	83	is	be	AUX
dti-1338	24	84	on	on	ADP
dti-1338	24	85	undifferentiated	undifferentiated	ADJ
dti-1338	24	86	mesenchymal	mesenchymal	NOUN
dti-1338	24	87	cell	cell	NOUN
dti-1338	24	88	proliferation	proliferation	NOUN
dti-1338	24	89	and	and	CCONJ
dti-1338	24	90	cell	cell	NOUN
dti-1338	24	91	differentiation	differentiation	NOUN
dti-1338	24	92	in	in	ADP
dti-1338	24	93	the	the	DET
dti-1338	24	94	presence	presence	NOUN
dti-1338	24	95	of	of	ADP
dti-1338	24	96	ecms	ecms	NOUN
dti-1338	24	97	,	,	PUNCT
dti-1338	24	98	especially	especially	ADV
dti-1338	24	99	to	to	ADP
dti-1338	24	100	fibronectin	fibronectin	NOUN
dti-1338	24	101	and	and	CCONJ
dti-1338	24	102	type	type	NOUN
dti-1338	24	103	i	i	PRON
dti-1338	24	104	collagen	collagen	VERB
dti-1338	24	105	.	.	PUNCT
dti-1338	25	1	the	the	DET
dti-1338	25	2	aim	aim	NOUN
dti-1338	25	3	of	of	ADP
dti-1338	25	4	this	this	DET
dti-1338	25	5	study	study	NOUN
dti-1338	25	6	is	be	AUX
dti-1338	25	7	to	to	PART
dti-1338	25	8	investigate	investigate	VERB
dti-1338	25	9	the	the	DET
dti-1338	25	10	effect	effect	NOUN
dti-1338	25	11	of	of	ADP
dti-1338	25	12	vpa	vpa	PROPN
dti-1338	25	13	on	on	ADP
dti-1338	25	14	the	the	DET
dti-1338	25	15	cell	cell	NOUN
dti-1338	25	16	differentiation	differentiation	NOUN
dti-1338	25	17	and	and	CCONJ
dti-1338	25	18	proliferation	proliferation	NOUN
dti-1338	25	19	of	of	ADP
dti-1338	25	20	mesenchymal	mesenchymal	NOUN
dti-1338	25	21	cells	cell	NOUN
dti-1338	25	22	which	which	PRON
dti-1338	25	23	can	can	AUX
dti-1338	25	24	differentiate	differentiate	VERB
dti-1338	25	25	into	into	ADP
dti-1338	25	26	cells	cell	NOUN
dti-1338	25	27	composed	compose	VERB
dti-1338	25	28	of	of	ADP
dti-1338	25	29	mesenchymal	mesenchymal	ADJ
dti-1338	25	30	tissues	tissue	NOUN
dti-1338	25	31	,	,	PUNCT
dti-1338	25	32	including	include	VERB
dti-1338	25	33	those	those	PRON
dti-1338	25	34	found	find	VERB
dti-1338	25	35	in	in	ADP
dti-1338	25	36	bone	bone	NOUN
dti-1338	25	37	.	.	PUNCT
dti-1338	26	1	we	we	PRON
dti-1338	26	2	observed	observe	VERB
dti-1338	26	3	a	a	DET
dti-1338	26	4	normal	normal	ADJ
dti-1338	26	5	mesenchymal	mesenchymal	NOUN
dti-1338	26	6	cell	cell	NOUN
dti-1338	26	7	shape	shape	NOUN
dti-1338	26	8	but	but	CCONJ
dti-1338	26	9	large	large	ADJ
dti-1338	26	10	number	number	NOUN
dti-1338	26	11	of	of	ADP
dti-1338	26	12	stress	stress	ADJ
dti-1338	26	13	fibers	fiber	NOUN
dti-1338	26	14	in	in	ADP
dti-1338	26	15	cells	cell	NOUN
dti-1338	26	16	in	in	ADP
dti-1338	26	17	the	the	DET
dti-1338	26	18	presence	presence	NOUN
dti-1338	26	19	of	of	ADP
dti-1338	26	20	a	a	DET
dti-1338	26	21	high	high	ADJ
dti-1338	26	22	concentration	concentration	NOUN
dti-1338	26	23	of	of	ADP
dti-1338	26	24	vpa	vpa	PROPN
dti-1338	26	25	,	,	PUNCT
dti-1338	26	26	and	and	CCONJ
dti-1338	26	27	these	these	DET
dti-1338	26	28	mesenchymal	mesenchymal	ADJ
dti-1338	26	29	cells	cell	NOUN
dti-1338	26	30	were	be	AUX
dti-1338	26	31	also	also	ADV
dti-1338	26	32	able	able	ADJ
dti-1338	26	33	to	to	PART
dti-1338	26	34	proliferate	proliferate	VERB
dti-1338	26	35	on	on	ADP
dti-1338	26	36	a	a	DET
dti-1338	26	37	non	non	ADJ
dti-1338	26	38	-	-	ADJ
dti-1338	26	39	coated	coated	ADJ
dti-1338	26	40	plastic	plastic	NOUN
dti-1338	26	41	plate	plate	NOUN
dti-1338	26	42	.	.	PUNCT
dti-1338	27	1	however	however	ADV
dti-1338	27	2	,	,	PUNCT
dti-1338	27	3	mesenchymal	mesenchymal	ADJ
dti-1338	27	4	cell	cell	NOUN
dti-1338	27	5	proliferation	proliferation	NOUN
dti-1338	27	6	was	be	AUX
dti-1338	27	7	inhibited	inhibit	VERB
dti-1338	27	8	when	when	SCONJ
dti-1338	27	9	cells	cell	NOUN
dti-1338	27	10	were	be	AUX
dti-1338	27	11	cultured	cultured	ADJ
dti-1338	27	12	on	on	ADP
dti-1338	27	13	ecm	ecm	NOUN
dti-1338	27	14	-	-	PUNCT
dti-1338	27	15	coated	coat	VERB
dti-1338	27	16	plates	plate	NOUN
dti-1338	27	17	,	,	PUNCT
dti-1338	27	18	even	even	ADV
dti-1338	27	19	in	in	ADP
dti-1338	27	20	low	low	ADJ
dti-1338	27	21	concentrations	concentration	NOUN
dti-1338	27	22	of	of	ADP
dti-1338	27	23	vpa	vpa	PROPN
dti-1338	27	24	,	,	PUNCT
dti-1338	27	25	and	and	CCONJ
dti-1338	27	26	vpa	vpa	PROPN
dti-1338	27	27	promoted	promote	VERB
dti-1338	27	28	the	the	DET
dti-1338	27	29	expression	expression	NOUN
dti-1338	27	30	of	of	ADP
dti-1338	27	31	osteoblastic	osteoblastic	ADJ
dti-1338	27	32	cell	cell	NOUN
dti-1338	27	33	marker	marker	NOUN
dti-1338	27	34	genes	gene	NOUN
dti-1338	27	35	.	.	PUNCT
dti-1338	28	1	in	in	ADP
dti-1338	28	2	an	an	DET
dti-1338	28	3	osteogenesis	osteogenesis	NOUN
dti-1338	28	4	-	-	PUNCT
dti-1338	28	5	inductive	inductive	ADJ
dti-1338	28	6	medium	medium	NOUN
dti-1338	28	7	,	,	PUNCT
dti-1338	28	8	vpa	vpa	PROPN
dti-1338	28	9	promoted	promote	VERB
dti-1338	28	10	osteogenesis	osteogenesis	NOUN
dti-1338	28	11	on	on	ADP
dti-1338	28	12	both	both	DET
dti-1338	28	13	noncoated	noncoate	VERB
dti-1338	28	14	plastic	plastic	NOUN
dti-1338	28	15	and	and	CCONJ
dti-1338	28	16	collagen	collagen	NOUN
dti-1338	28	17	-	-	PUNCT
dti-1338	28	18	coated	coat	VERB
dti-1338	28	19	plates	plate	NOUN
dti-1338	28	20	.	.	PUNCT
dti-1338	29	1	these	these	DET
dti-1338	29	2	observations	observation	NOUN
dti-1338	29	3	may	may	AUX
dti-1338	29	4	reflect	reflect	VERB
dti-1338	29	5	the	the	DET
dti-1338	29	6	in	in	ADP
dti-1338	29	7	vivo	vivo	ADJ
dti-1338	29	8	cell	cell	NOUN
dti-1338	29	9	conditions	condition	NOUN
dti-1338	29	10	and	and	CCONJ
dti-1338	29	11	provide	provide	VERB
dti-1338	29	12	further	further	ADJ
dti-1338	29	13	insight	insight	NOUN
dti-1338	29	14	into	into	ADP
dti-1338	29	15	the	the	DET
dti-1338	29	16	osteoblastic	osteoblastic	ADJ
dti-1338	29	17	cell	cell	NOUN
dti-1338	29	18	differentiation	differentiation	NOUN
dti-1338	29	19	mechanism	mechanism	NOUN
dti-1338	29	20	caused	cause	VERB
dti-1338	29	21	by	by	ADP
dti-1338	29	22	vpa	vpa	PROPN
dti-1338	29	23	.	.	PUNCT
dti-1338	30	1	materials	material	NOUN
dti-1338	30	2	and	and	CCONJ
dti-1338	30	3	methods	method	NOUN
dti-1338	30	4	cell	cell	NOUN
dti-1338	30	5	culture	culture	NOUN
dti-1338	30	6	a	a	DET
dti-1338	30	7	mouse	mouse	NOUN
dti-1338	30	8	embryonic	embryonic	ADJ
dti-1338	30	9	mesenchymal	mesenchymal	ADJ
dti-1338	30	10	cell	cell	NOUN
dti-1338	30	11	line	line	NOUN
dti-1338	30	12	,	,	PUNCT
dti-1338	30	13	c3h10t1/2	c3h10t1/2	PROPN
dti-1338	30	14	clone	clone	NOUN
dti-1338	30	15	8	8	NUM
dti-1338	30	16	cells	cell	NOUN
dti-1338	30	17	,	,	PUNCT
dti-1338	30	18	was	be	AUX
dti-1338	30	19	obtained	obtain	VERB
dti-1338	30	20	from	from	ADP
dti-1338	30	21	riken	riken	VERB
dti-1338	30	22	bioresource	bioresource	PROPN
dti-1338	30	23	center	center	PROPN
dti-1338	30	24	cell	cell	NOUN
dti-1338	30	25	bank	bank	NOUN
dti-1338	30	26	(	(	PUNCT
dti-1338	30	27	tsukuba	tsukuba	PROPN
dti-1338	30	28	,	,	PUNCT
dti-1338	30	29	japan	japan	PROPN
dti-1338	30	30	)	)	PUNCT
dti-1338	30	31	.	.	PUNCT
dti-1338	31	1	cells	cell	NOUN
dti-1338	31	2	were	be	AUX
dti-1338	31	3	cultured	cultured	ADJ
dti-1338	31	4	in	in	ADP
dti-1338	31	5	basal	basal	ADJ
dti-1338	31	6	medium	medium	PROPN
dti-1338	31	7	eagle	eagle	PROPN
dti-1338	31	8	(	(	PUNCT
dti-1338	31	9	bme	bme	NOUN
dti-1338	31	10	)	)	PUNCT
dti-1338	31	11	containing	contain	VERB
dti-1338	31	12	10	10	NUM
dti-1338	31	13	%	%	NOUN
dti-1338	31	14	fetal	fetal	ADJ
dti-1338	31	15	bovine	bovine	NOUN
dti-1338	31	16	serum	serum	NOUN
dti-1338	31	17	(	(	PUNCT
dti-1338	31	18	fbs	fbs	PROPN
dti-1338	31	19	,	,	PUNCT
dti-1338	31	20	equitechbio	equitechbio	PROPN
dti-1338	31	21	inc	inc	PROPN
dti-1338	31	22	.	.	PROPN
dti-1338	31	23	,	,	PUNCT
dti-1338	31	24	tokyo	tokyo	PROPN
dti-1338	31	25	,	,	PUNCT
dti-1338	31	26	japan	japan	PROPN
dti-1338	31	27	)	)	PUNCT
dti-1338	31	28	and	and	CCONJ
dti-1338	31	29	antibiotics	antibiotic	NOUN
dti-1338	31	30	(	(	PUNCT
dti-1338	31	31	100	100	NUM
dti-1338	31	32	u	u	NOUN
dti-1338	31	33	/	/	SYM
dti-1338	31	34	ml	ml	NOUN
dti-1338	31	35	of	of	ADP
dti-1338	31	36	penicillin	penicillin	PROPN
dti-1338	31	37	-	-	PUNCT
dti-1338	31	38	g	g	PROPN
dti-1338	31	39	and	and	CCONJ
dti-1338	31	40	100	100	NUM
dti-1338	31	41	mg	mg	NUM
dti-1338	31	42	/	/	SYM
dti-1338	31	43	ml	ml	PROPN
dti-1338	31	44	of	of	ADP
dti-1338	31	45	streptomycin	streptomycin	PROPN
dti-1338	31	46	)	)	PUNCT
dti-1338	31	47	at	at	ADP
dti-1338	31	48	37	37	NUM
dti-1338	31	49	°	°	SYM
dti-1338	31	50	c	c	NOUN
dti-1338	31	51	in	in	ADP
dti-1338	31	52	a	a	DET
dti-1338	31	53	humidified	humidify	VERB
dti-1338	31	54	atmosphere	atmosphere	NOUN
dti-1338	31	55	of	of	ADP
dti-1338	31	56	5	5	NUM
dti-1338	31	57	%	%	NOUN
dti-1338	31	58	co2	co2	NOUN
dti-1338	31	59	in	in	ADP
dti-1338	31	60	air	air	NOUN
dti-1338	31	61	.	.	PUNCT
dti-1338	32	1	the	the	DET
dti-1338	32	2	medium	medium	NOUN
dti-1338	32	3	was	be	AUX
dti-1338	32	4	changed	change	VERB
dti-1338	32	5	twice	twice	ADV
dti-1338	32	6	a	a	DET
dti-1338	32	7	week	week	NOUN
dti-1338	32	8	.	.	PUNCT
dti-1338	33	1	before	before	ADP
dti-1338	33	2	reaching	reach	VERB
dti-1338	33	3	confluence	confluence	NOUN
dti-1338	33	4	,	,	PUNCT
dti-1338	33	5	the	the	DET
dti-1338	33	6	cells	cell	NOUN
dti-1338	33	7	were	be	AUX
dti-1338	33	8	passaged	passage	VERB
dti-1338	33	9	for	for	ADP
dti-1338	33	10	use	use	NOUN
dti-1338	33	11	in	in	ADP
dti-1338	33	12	experiments	experiment	NOUN
dti-1338	33	13	.	.	PUNCT
dti-1338	34	1	vpa	vpa	PROPN
dti-1338	34	2	(	(	PUNCT
dti-1338	34	3	valproic	valproic	ADJ
dti-1338	34	4	acid	acid	NOUN
dti-1338	34	5	sodium	sodium	NOUN
dti-1338	34	6	,	,	PUNCT
dti-1338	34	7	m.w	m.w	PROPN
dti-1338	34	8	.	.	PUNCT
dti-1338	34	9	=	=	SYM
dti-1338	34	10	166.19	166.19	NUM
dti-1338	34	11	)	)	PUNCT
dti-1338	34	12	was	be	AUX
dti-1338	34	13	purchased	purchase	VERB
dti-1338	34	14	from	from	ADP
dti-1338	34	15	wako	wako	PROPN
dti-1338	34	16	(	(	PUNCT
dti-1338	34	17	tokyo	tokyo	PROPN
dti-1338	34	18	,	,	PUNCT
dti-1338	34	19	japan	japan	PROPN
dti-1338	34	20	)	)	PUNCT
dti-1338	34	21	,	,	PUNCT
dti-1338	34	22	diluted	dilute	VERB
dti-1338	34	23	in	in	ADP
dti-1338	34	24	sterilized	sterilize	VERB
dti-1338	34	25	phosphate	phosphate	NOUN
dti-1338	34	26	-	-	PUNCT
dti-1338	34	27	buffered	buffer	VERB
dti-1338	34	28	saline	saline	NOUN
dti-1338	34	29	at	at	ADP
dti-1338	34	30	100	100	NUM
dti-1338	34	31	mg	mg	NUM
dti-1338	34	32	/	/	SYM
dti-1338	34	33	ml	ml	NOUN
dti-1338	34	34	,	,	PUNCT
dti-1338	34	35	and	and	CCONJ
dti-1338	34	36	added	add	VERB
dti-1338	34	37	to	to	ADP
dti-1338	34	38	c3h10t1/2	c3h10t1/2	PROPN
dti-1338	34	39	at	at	ADP
dti-1338	34	40	various	various	ADJ
dti-1338	34	41	final	final	ADJ
dti-1338	34	42	concentrations	concentration	NOUN
dti-1338	34	43	for	for	ADP
dti-1338	34	44	indicated	indicate	VERB
dti-1338	34	45	periods	period	NOUN
dti-1338	34	46	of	of	ADP
dti-1338	34	47	time	time	NOUN
dti-1338	34	48	.	.	PUNCT
dti-1338	35	1	cell	cell	NOUN
dti-1338	35	2	counting	count	VERB
dti-1338	35	3	the	the	DET
dti-1338	35	4	proportional	proportional	ADJ
dti-1338	35	5	values	value	NOUN
dti-1338	35	6	of	of	ADP
dti-1338	35	7	cells	cell	NOUN
dti-1338	35	8	were	be	AUX
dti-1338	35	9	counted	count	VERB
dti-1338	35	10	using	use	VERB
dti-1338	35	11	cell	cell	NOUN
dti-1338	35	12	-	-	PUNCT
dti-1338	35	13	counting	counting	NOUN
dti-1338	35	14	kit-8	kit-8	PUNCT
dti-1338	35	15	(	(	PUNCT
dti-1338	35	16	dojindo	dojindo	PROPN
dti-1338	35	17	laboratories	laboratory	NOUN
dti-1338	35	18	,	,	PUNCT
dti-1338	35	19	kumamoto	kumamoto	PROPN
dti-1338	35	20	,	,	PUNCT
dti-1338	35	21	japan	japan	PROPN
dti-1338	35	22	)	)	PUNCT
dti-1338	35	23	,	,	PUNCT
dti-1338	35	24	which	which	PRON
dti-1338	35	25	measures	measure	VERB
dti-1338	35	26	a	a	DET
dti-1338	35	27	highly	highly	ADV
dti-1338	35	28	watersoluble	watersoluble	ADJ
dti-1338	35	29	formazan	formazan	ADJ
dti-1338	35	30	dye	dye	NOUN
dti-1338	35	31	produced	produce	VERB
dti-1338	35	32	from	from	ADP
dti-1338	35	33	tetrazolium	tetrazolium	NOUN
dti-1338	35	34	salts	salt	NOUN
dti-1338	35	35	.	.	PUNCT
dti-1338	36	1	cells	cell	NOUN
dti-1338	36	2	were	be	AUX
dti-1338	36	3	seeded	seed	VERB
dti-1338	36	4	at	at	ADP
dti-1338	36	5	1.0	1.0	NUM
dti-1338	36	6	×	×	NOUN
dti-1338	36	7	103	103	NUM
dti-1338	36	8	cells	cell	NOUN
dti-1338	36	9	per	per	ADP
dti-1338	36	10	well	well	ADV
dti-1338	36	11	on	on	ADP
dti-1338	36	12	a	a	DET
dti-1338	36	13	96	96	NUM
dti-1338	36	14	-	-	PUNCT
dti-1338	36	15	well	well	NOUN
dti-1338	36	16	plate	plate	NOUN
dti-1338	36	17	and	and	CCONJ
dti-1338	36	18	the	the	DET
dti-1338	36	19	medium	medium	NOUN
dti-1338	36	20	was	be	AUX
dti-1338	36	21	changed	change	VERB
dti-1338	36	22	,	,	PUNCT
dti-1338	36	23	along	along	ADP
dti-1338	36	24	with	with	ADP
dti-1338	36	25	various	various	ADJ
dti-1338	36	26	concentrations	concentration	NOUN
dti-1338	36	27	of	of	ADP
dti-1338	36	28	vpa	vpa	PROPN
dti-1338	36	29	,	,	PUNCT
dti-1338	36	30	after	after	ADP
dti-1338	36	31	cell	cell	NOUN
dti-1338	36	32	attachment	attachment	NOUN
dti-1338	36	33	to	to	ADP
dti-1338	36	34	non	non	ADJ
dti-1338	36	35	-	-	ADJ
dti-1338	36	36	coated	coated	ADJ
dti-1338	36	37	plastic	plastic	NOUN
dti-1338	36	38	,	,	PUNCT
dti-1338	36	39	type	type	NOUN
dti-1338	36	40	i	i	PRON
dti-1338	36	41	collagen	collagen	NOUN
dti-1338	36	42	-	-	PUNCT
dti-1338	36	43	coated	coated	ADJ
dti-1338	36	44	and	and	CCONJ
dti-1338	36	45	fibronectin	fibronectin	NOUN
dti-1338	36	46	-	-	PUNCT
dti-1338	36	47	coated	coat	VERB
dti-1338	36	48	96	96	NUM
dti-1338	36	49	-	-	PUNCT
dti-1338	36	50	well	well	NOUN
dti-1338	36	51	plates	plate	NOUN
dti-1338	36	52	(	(	PUNCT
dti-1338	36	53	becton	becton	PROPN
dti-1338	36	54	-	-	PUNCT
dti-1338	36	55	dickinson	dickinson	PROPN
dti-1338	36	56	,	,	PUNCT
dti-1338	36	57	tokyo	tokyo	PROPN
dti-1338	36	58	,	,	PUNCT
dti-1338	36	59	japan	japan	PROPN
dti-1338	36	60	)	)	PUNCT
dti-1338	36	61	.	.	PUNCT
dti-1338	37	1	after	after	ADP
dti-1338	37	2	48and	48and	NOUN
dti-1338	37	3	96	96	NUM
dti-1338	37	4	-	-	PUNCT
dti-1338	37	5	hour	hour	NOUN
dti-1338	37	6	cell	cell	NOUN
dti-1338	37	7	cultures	culture	NOUN
dti-1338	37	8	,	,	PUNCT
dti-1338	37	9	cells	cell	NOUN
dti-1338	37	10	were	be	AUX
dti-1338	37	11	incubated	incubate	VERB
dti-1338	37	12	with	with	ADP
dti-1338	37	13	the	the	DET
dti-1338	37	14	counting	counting	NOUN
dti-1338	37	15	reagent	reagent	NOUN
dti-1338	37	16	for	for	ADP
dti-1338	37	17	one	one	NUM
dti-1338	37	18	hour	hour	NOUN
dti-1338	37	19	,	,	PUNCT
dti-1338	37	20	according	accord	VERB
dti-1338	37	21	to	to	ADP
dti-1338	37	22	the	the	DET
dti-1338	37	23	manufacturer	manufacturer	NOUN
dti-1338	37	24	’s	’s	PART
dti-1338	37	25	instructions	instruction	NOUN
dti-1338	37	26	,	,	PUNCT
dti-1338	37	27	and	and	CCONJ
dti-1338	37	28	the	the	DET
dti-1338	37	29	relative	relative	ADJ
dti-1338	37	30	cell	cell	NOUN
dti-1338	37	31	number	number	NOUN
dti-1338	37	32	was	be	AUX
dti-1338	37	33	determined	determine	VERB
dti-1338	37	34	by	by	ADP
dti-1338	37	35	measuring	measure	VERB
dti-1338	37	36	light	light	ADJ
dti-1338	37	37	absorbance	absorbance	NOUN
dti-1338	37	38	at	at	ADP
dti-1338	37	39	a	a	DET
dti-1338	37	40	wavelength	wavelength	NOUN
dti-1338	37	41	of	of	ADP
dti-1338	37	42	450	450	NUM
dti-1338	37	43	nm	nm	NOUN
dti-1338	37	44	of	of	ADP
dti-1338	37	45	the	the	DET
dti-1338	37	46	formazan	formazan	ADJ
dti-1338	37	47	dye	dye	NOUN
dti-1338	37	48	product	product	NOUN
dti-1338	37	49	in	in	ADP
dti-1338	37	50	the	the	DET
dti-1338	37	51	cultures	culture	NOUN
dti-1338	37	52	.	.	PUNCT
dti-1338	38	1	to	to	PART
dti-1338	38	2	determine	determine	VERB
dti-1338	38	3	the	the	DET
dti-1338	38	4	http://www.la-press.com	http://www.la-press.com	NOUN
dti-1338	38	5	the	the	DET
dti-1338	38	6	effect	effect	NOUN
dti-1338	38	7	of	of	ADP
dti-1338	38	8	vpa	vpa	PROPN
dti-1338	38	9	on	on	ADP
dti-1338	38	10	mesenchymal	mesenchymal	ADJ
dti-1338	38	11	cell	cell	NOUN
dti-1338	38	12	in	in	ADP
dti-1338	38	13	ecm	ecm	PROPN
dti-1338	38	14	drug	drug	NOUN
dti-1338	38	15	target	target	NOUN
dti-1338	38	16	insights	insight	NOUN
dti-1338	38	17	2011:5	2011:5	NUM
dti-1338	38	18	3	3	NUM
dti-1338	38	19	number	number	NOUN
dti-1338	38	20	of	of	ADP
dti-1338	38	21	viable	viable	ADJ
dti-1338	38	22	cells	cell	NOUN
dti-1338	38	23	cultured	cultured	ADJ
dti-1338	38	24	in	in	ADP
dti-1338	38	25	vpa	vpa	PROPN
dti-1338	38	26	,	,	PUNCT
dti-1338	38	27	a	a	DET
dti-1338	38	28	trypan	trypan	NOUN
dti-1338	38	29	blue	blue	ADJ
dti-1338	38	30	dye	dye	NOUN
dti-1338	38	31	exclusion	exclusion	NOUN
dti-1338	38	32	test	test	NOUN
dti-1338	38	33	was	be	AUX
dti-1338	38	34	used	use	VERB
dti-1338	38	35	.	.	PUNCT
dti-1338	39	1	mesenchymal	mesenchymal	ADJ
dti-1338	39	2	cells	cell	NOUN
dti-1338	39	3	were	be	AUX
dti-1338	39	4	cultured	cultured	ADJ
dti-1338	39	5	at	at	ADP
dti-1338	39	6	various	various	ADJ
dti-1338	39	7	concentration	concentration	NOUN
dti-1338	39	8	of	of	ADP
dti-1338	39	9	vpa	vpa	PROPN
dti-1338	39	10	for	for	ADP
dti-1338	39	11	48	48	NUM
dti-1338	39	12	hours	hour	NOUN
dti-1338	39	13	and	and	CCONJ
dti-1338	39	14	96	96	NUM
dti-1338	39	15	hours	hour	NOUN
dti-1338	39	16	on	on	ADP
dti-1338	39	17	the	the	DET
dti-1338	39	18	non	non	ADJ
dti-1338	39	19	-	-	ADJ
dti-1338	39	20	coated	coated	ADJ
dti-1338	39	21	plastic	plastic	NOUN
dti-1338	39	22	,	,	PUNCT
dti-1338	39	23	fibronectin	fibronectin	NOUN
dti-1338	39	24	and	and	CCONJ
dti-1338	39	25	type	type	NOUN
dti-1338	39	26	i	i	PRON
dti-1338	39	27	collagen	collagen	NOUN
dti-1338	39	28	-	-	PUNCT
dti-1338	39	29	coated	coat	VERB
dti-1338	39	30	24	24	NUM
dti-1338	39	31	-	-	PUNCT
dti-1338	39	32	well	well	NOUN
dti-1338	39	33	plate	plate	NOUN
dti-1338	39	34	.	.	PUNCT
dti-1338	40	1	after	after	ADP
dti-1338	40	2	cell	cell	NOUN
dti-1338	40	3	culture	culture	NOUN
dti-1338	40	4	,	,	PUNCT
dti-1338	40	5	0.4	0.4	NUM
dti-1338	40	6	%	%	NOUN
dti-1338	40	7	solution	solution	NOUN
dti-1338	40	8	of	of	ADP
dti-1338	40	9	trypan	trypan	NOUN
dti-1338	40	10	blue	blue	NOUN
dti-1338	40	11	was	be	AUX
dti-1338	40	12	added	add	VERB
dti-1338	40	13	to	to	ADP
dti-1338	40	14	equal	equal	ADJ
dti-1338	40	15	volumes	volume	NOUN
dti-1338	40	16	of	of	ADP
dti-1338	40	17	the	the	DET
dti-1338	40	18	harvested	harvest	VERB
dti-1338	40	19	cell	cell	NOUN
dti-1338	40	20	suspensions	suspension	NOUN
dti-1338	40	21	.	.	PUNCT
dti-1338	41	1	the	the	DET
dti-1338	41	2	ratio	ratio	NOUN
dti-1338	41	3	of	of	ADP
dti-1338	41	4	stained	stain	VERB
dti-1338	41	5	to	to	ADP
dti-1338	41	6	unstained	unstained	ADJ
dti-1338	41	7	cells	cell	NOUN
dti-1338	41	8	was	be	AUX
dti-1338	41	9	estimated	estimate	VERB
dti-1338	41	10	using	use	VERB
dti-1338	41	11	a	a	DET
dti-1338	41	12	hemocytometer	hemocytometer	NOUN
dti-1338	41	13	.	.	PUNCT
dti-1338	42	1	proliferating	proliferate	VERB
dti-1338	42	2	cell	cell	NOUN
dti-1338	42	3	nuclear	nuclear	ADJ
dti-1338	42	4	antigen	antigen	NOUN
dti-1338	42	5	(	(	PUNCT
dti-1338	42	6	pcna	pcna	NOUN
dti-1338	42	7	)	)	PUNCT
dti-1338	42	8	staining	stain	VERB
dti-1338	42	9	and	and	CCONJ
dti-1338	42	10	cytoskeleton	cytoskeleton	NOUN
dti-1338	42	11	staining	stain	VERB
dti-1338	42	12	before	before	ADP
dti-1338	42	13	the	the	DET
dti-1338	42	14	experiment	experiment	NOUN
dti-1338	42	15	,	,	PUNCT
dti-1338	42	16	c3h10t1/2	c3h10t1/2	PROPN
dti-1338	42	17	cells	cell	NOUN
dti-1338	42	18	were	be	AUX
dti-1338	42	19	trypsinized	trypsinize	VERB
dti-1338	42	20	from	from	ADP
dti-1338	42	21	a	a	DET
dti-1338	42	22	standard	standard	ADJ
dti-1338	42	23	tissue	tissue	NOUN
dti-1338	42	24	culture	culture	NOUN
dti-1338	42	25	plate	plate	NOUN
dti-1338	42	26	and	and	CCONJ
dti-1338	42	27	seeded	seed	VERB
dti-1338	42	28	in	in	ADP
dti-1338	42	29	a	a	DET
dti-1338	42	30	lab	lab	NOUN
dti-1338	42	31	-	-	PUNCT
dti-1338	42	32	tek	tek	PROPN
dti-1338	42	33	chamber	chamber	PROPN
dti-1338	42	34	slide	slide	NOUN
dti-1338	42	35	(	(	PUNCT
dti-1338	42	36	nalge	nalge	NOUN
dti-1338	42	37	nunc	nunc	PROPN
dti-1338	42	38	,	,	PUNCT
dti-1338	42	39	tokyo	tokyo	PROPN
dti-1338	42	40	,	,	PUNCT
dti-1338	42	41	japan	japan	PROPN
dti-1338	42	42	)	)	PUNCT
dti-1338	42	43	,	,	PUNCT
dti-1338	42	44	to	to	PART
dti-1338	42	45	which	which	PRON
dti-1338	42	46	they	they	PRON
dti-1338	42	47	adhered	adhere	VERB
dti-1338	42	48	during	during	ADP
dti-1338	42	49	incubation	incubation	NOUN
dti-1338	42	50	overnight	overnight	ADV
dti-1338	42	51	in	in	ADP
dti-1338	42	52	a	a	DET
dti-1338	42	53	standard	standard	ADJ
dti-1338	42	54	medium	medium	NOUN
dti-1338	42	55	.	.	PUNCT
dti-1338	43	1	after	after	ADP
dti-1338	43	2	cell	cell	NOUN
dti-1338	43	3	adherence	adherence	NOUN
dti-1338	43	4	,	,	PUNCT
dti-1338	43	5	they	they	PRON
dti-1338	43	6	were	be	AUX
dti-1338	43	7	cultured	cultured	ADJ
dti-1338	43	8	for	for	ADP
dti-1338	43	9	an	an	DET
dti-1338	43	10	additional	additional	ADJ
dti-1338	43	11	48	48	NUM
dti-1338	43	12	hours	hour	NOUN
dti-1338	43	13	after	after	ADP
dti-1338	43	14	changing	change	VERB
dti-1338	43	15	the	the	DET
dti-1338	43	16	medium	medium	NOUN
dti-1338	43	17	to	to	PART
dti-1338	43	18	include	include	VERB
dti-1338	43	19	vpa	vpa	PROPN
dti-1338	43	20	concentrations	concentration	NOUN
dti-1338	43	21	of	of	ADP
dti-1338	43	22	10	10	NUM
dti-1338	43	23	,	,	PUNCT
dti-1338	43	24	100	100	NUM
dti-1338	43	25	and	and	CCONJ
dti-1338	43	26	1000	1000	NUM
dti-1338	43	27	µg	µg	NOUN
dti-1338	43	28	/	/	SYM
dti-1338	43	29	ml	ml	NOUN
dti-1338	43	30	.	.	PUNCT
dti-1338	44	1	after	after	ADP
dti-1338	44	2	an	an	DET
dti-1338	44	3	additional	additional	ADJ
dti-1338	44	4	48	48	NUM
dti-1338	44	5	-	-	PUNCT
dti-1338	44	6	hour	hour	NOUN
dti-1338	44	7	culture	culture	NOUN
dti-1338	44	8	,	,	PUNCT
dti-1338	44	9	cells	cell	NOUN
dti-1338	44	10	were	be	AUX
dti-1338	44	11	fixed	fix	VERB
dti-1338	44	12	with	with	ADP
dti-1338	44	13	4	4	NUM
dti-1338	44	14	%	%	NOUN
dti-1338	44	15	paraformaldehyde	paraformaldehyde	NOUN
dti-1338	44	16	in	in	ADP
dti-1338	44	17	0.01	0.01	NUM
dti-1338	44	18	m	m	VERB
dti-1338	44	19	phosphate	phosphate	NOUN
dti-1338	44	20	-	-	PUNCT
dti-1338	44	21	buffered	buffer	VERB
dti-1338	44	22	saline	saline	NOUN
dti-1338	44	23	(	(	PUNCT
dti-1338	44	24	pbs	pbs	PROPN
dti-1338	44	25	)	)	PUNCT
dti-1338	44	26	and	and	CCONJ
dti-1338	44	27	proliferating	proliferate	VERB
dti-1338	44	28	cell	cell	NOUN
dti-1338	44	29	nuclear	nuclear	ADJ
dti-1338	44	30	antigen	antigen	NOUN
dti-1338	44	31	(	(	PUNCT
dti-1338	44	32	pcna	pcna	PROPN
dti-1338	44	33	)	)	PUNCT
dti-1338	44	34	and	and	CCONJ
dti-1338	44	35	cyctoskeleton	cyctoskeleton	PROPN
dti-1338	44	36	staining	stain	VERB
dti-1338	44	37	was	be	AUX
dti-1338	44	38	performed	perform	VERB
dti-1338	44	39	.	.	PUNCT
dti-1338	45	1	pcna	pcna	PROPN
dti-1338	45	2	was	be	AUX
dti-1338	45	3	detected	detect	VERB
dti-1338	45	4	by	by	ADP
dti-1338	45	5	a	a	DET
dti-1338	45	6	zymed	zyme	VERB
dti-1338	45	7	pcna	pcna	NOUN
dti-1338	45	8	staining	stain	VERB
dti-1338	45	9	kit	kit	NOUN
dti-1338	45	10	(	(	PUNCT
dti-1338	45	11	invitrogen	invitrogen	PROPN
dti-1338	45	12	,	,	PUNCT
dti-1338	45	13	tokyo	tokyo	PROPN
dti-1338	45	14	,	,	PUNCT
dti-1338	45	15	japan	japan	PROPN
dti-1338	45	16	)	)	PUNCT
dti-1338	45	17	according	accord	VERB
dti-1338	45	18	to	to	ADP
dti-1338	45	19	the	the	DET
dti-1338	45	20	manufacturer	manufacturer	NOUN
dti-1338	45	21	’s	’s	PART
dti-1338	45	22	instructions	instruction	NOUN
dti-1338	45	23	.	.	PUNCT
dti-1338	46	1	briefly	briefly	ADV
dti-1338	46	2	,	,	PUNCT
dti-1338	46	3	after	after	ADP
dti-1338	46	4	fixation	fixation	NOUN
dti-1338	46	5	,	,	PUNCT
dti-1338	46	6	cells	cell	NOUN
dti-1338	46	7	were	be	AUX
dti-1338	46	8	incubated	incubate	VERB
dti-1338	46	9	with	with	ADP
dti-1338	46	10	blocking	block	VERB
dti-1338	46	11	solution	solution	NOUN
dti-1338	46	12	and	and	CCONJ
dti-1338	46	13	incubated	incubate	VERB
dti-1338	46	14	with	with	ADP
dti-1338	46	15	biotinylated	biotinylate	VERB
dti-1338	46	16	mouse	mouse	NOUN
dti-1338	46	17	anti	anti	NOUN
dti-1338	46	18	-	-	NOUN
dti-1338	46	19	pcna	pcna	NOUN
dti-1338	46	20	for	for	ADP
dti-1338	46	21	60	60	NUM
dti-1338	46	22	minutes	minute	NOUN
dti-1338	46	23	at	at	ADP
dti-1338	46	24	room	room	NOUN
dti-1338	46	25	temperature	temperature	NOUN
dti-1338	46	26	.	.	PUNCT
dti-1338	47	1	the	the	DET
dti-1338	47	2	color	color	NOUN
dti-1338	47	3	was	be	AUX
dti-1338	47	4	developed	develop	VERB
dti-1338	47	5	using	use	VERB
dti-1338	47	6	diaminobenzidine	diaminobenzidine	NOUN
dti-1338	47	7	(	(	PUNCT
dti-1338	47	8	dab	dab	PROPN
dti-1338	47	9	)	)	PUNCT
dti-1338	47	10	as	as	SCONJ
dti-1338	47	11	the	the	DET
dti-1338	47	12	substrate	substrate	NOUN
dti-1338	47	13	included	include	VERB
dti-1338	47	14	in	in	ADP
dti-1338	47	15	the	the	DET
dti-1338	47	16	kit	kit	NOUN
dti-1338	47	17	.	.	PUNCT
dti-1338	48	1	negative	negative	ADJ
dti-1338	48	2	cells	cell	NOUN
dti-1338	48	3	were	be	AUX
dti-1338	48	4	counterstained	counterstaine	VERB
dti-1338	48	5	with	with	ADP
dti-1338	48	6	hematoxylin	hematoxylin	NOUN
dti-1338	48	7	.	.	PUNCT
dti-1338	49	1	the	the	DET
dti-1338	49	2	pcna	pcna	NOUN
dti-1338	49	3	-	-	PUNCT
dti-1338	49	4	positive	positive	ADJ
dti-1338	49	5	cell	cell	NOUN
dti-1338	49	6	counts	count	NOUN
dti-1338	49	7	were	be	AUX
dti-1338	49	8	expressed	express	VERB
dti-1338	49	9	as	as	ADP
dti-1338	49	10	a	a	DET
dti-1338	49	11	ratio	ratio	NOUN
dti-1338	49	12	of	of	ADP
dti-1338	49	13	total	total	ADJ
dti-1338	49	14	cells	cell	NOUN
dti-1338	49	15	,	,	PUNCT
dti-1338	49	16	including	include	VERB
dti-1338	49	17	both	both	CCONJ
dti-1338	49	18	positive	positive	ADJ
dti-1338	49	19	and	and	CCONJ
dti-1338	49	20	negative	negative	ADJ
dti-1338	49	21	pcna	pcna	NOUN
dti-1338	49	22	within	within	ADP
dti-1338	49	23	a	a	DET
dti-1338	49	24	defined	define	VERB
dti-1338	49	25	area	area	NOUN
dti-1338	49	26	of	of	ADP
dti-1338	49	27	500	500	NUM
dti-1338	49	28	µm²	µm²	NOUN
dti-1338	49	29	taken	take	VERB
dti-1338	49	30	from	from	ADP
dti-1338	49	31	five	five	NUM
dti-1338	49	32	different	different	ADJ
dti-1338	49	33	areas	area	NOUN
dti-1338	49	34	in	in	ADP
dti-1338	49	35	each	each	DET
dti-1338	49	36	test	test	NOUN
dti-1338	49	37	group	group	NOUN
dti-1338	49	38	.	.	PUNCT
dti-1338	50	1	for	for	ADP
dti-1338	50	2	f	f	NOUN
dti-1338	50	3	-	-	PUNCT
dti-1338	50	4	actin	actin	NOUN
dti-1338	50	5	cytoskeleton	cytoskeleton	PROPN
dti-1338	50	6	observation	observation	NOUN
dti-1338	50	7	,	,	PUNCT
dti-1338	50	8	cells	cell	NOUN
dti-1338	50	9	were	be	AUX
dti-1338	50	10	incubated	incubate	VERB
dti-1338	50	11	with	with	ADP
dti-1338	50	12	molecular	molecular	ADJ
dti-1338	50	13	probes	probe	NOUN
dti-1338	50	14	alexa	alexa	ADJ
dti-1338	50	15	fluor	fluor	NOUN
dti-1338	50	16	488	488	NUM
dti-1338	50	17	-	-	PUNCT
dti-1338	50	18	fitc	fitc	NOUN
dti-1338	50	19	(	(	PUNCT
dti-1338	50	20	invitrogen	invitrogen	PROPN
dti-1338	50	21	)	)	PUNCT
dti-1338	50	22	and	and	CCONJ
dti-1338	50	23	dna	dna	PROPN
dti-1338	50	24	stained	stain	VERB
dti-1338	50	25	with	with	ADP
dti-1338	50	26	1	1	NUM
dti-1338	50	27	,	,	PUNCT
dti-1338	50	28	4	4	NUM
dti-1338	50	29	,	,	PUNCT
dti-1338	50	30	6	6	NUM
dti-1338	50	31	-	-	PUNCT
dti-1338	50	32	diamidino-2	diamidino-2	NOUN
dti-1338	50	33	-	-	PUNCT
dti-1338	50	34	phenylindole	phenylindole	NOUN
dti-1338	50	35	(	(	PUNCT
dti-1338	50	36	dapi	dapi	ADJ
dti-1338	50	37	)	)	PUNCT
dti-1338	50	38	.	.	PUNCT
dti-1338	51	1	semi	semi	ADJ
dti-1338	51	2	-	-	ADJ
dti-1338	51	3	quantitative	quantitative	ADJ
dti-1338	51	4	reverse	reverse	ADJ
dti-1338	51	5	transcription	transcription	NOUN
dti-1338	51	6	polymerase	polymerase	NOUN
dti-1338	51	7	chain	chain	NOUN
dti-1338	51	8	reaction	reaction	NOUN
dti-1338	51	9	(	(	PUNCT
dti-1338	51	10	rt	rt	ADJ
dti-1338	51	11	-	-	PUNCT
dti-1338	51	12	pcr	pcr	NOUN
dti-1338	51	13	)	)	PUNCT
dti-1338	51	14	mouse	mouse	NOUN
dti-1338	51	15	mesenchymal	mesenchymal	ADJ
dti-1338	51	16	cells	cell	NOUN
dti-1338	51	17	were	be	AUX
dti-1338	51	18	cultured	cultured	ADJ
dti-1338	51	19	on	on	ADP
dti-1338	51	20	a	a	DET
dti-1338	51	21	non	non	ADJ
dti-1338	51	22	-	-	ADJ
dti-1338	51	23	coated	coated	ADJ
dti-1338	51	24	plastic	plastic	NOUN
dti-1338	51	25	or	or	CCONJ
dti-1338	51	26	type	type	NOUN
dti-1338	51	27	i	i	PRON
dti-1338	51	28	collagen	collagen	NOUN
dti-1338	51	29	-	-	PUNCT
dti-1338	51	30	coated	coated	ADJ
dti-1338	51	31	plate	plate	NOUN
dti-1338	51	32	in	in	ADP
dti-1338	51	33	the	the	DET
dti-1338	51	34	absence	absence	NOUN
dti-1338	51	35	or	or	CCONJ
dti-1338	51	36	presence	presence	NOUN
dti-1338	51	37	of	of	ADP
dti-1338	51	38	1	1	NUM
dti-1338	51	39	µg	µg	NOUN
dti-1338	51	40	/	/	SYM
dti-1338	51	41	ml	ml	ADP
dti-1338	51	42	vpa	vpa	PROPN
dti-1338	51	43	in	in	ADP
dti-1338	51	44	alpha	alpha	NOUN
dti-1338	51	45	-	-	PUNCT
dti-1338	51	46	modified	modify	VERB
dti-1338	51	47	eagle	eagle	NOUN
dti-1338	51	48	’s	’s	PART
dti-1338	51	49	minimum	minimum	ADJ
dti-1338	51	50	essential	essential	ADJ
dti-1338	51	51	medium	medium	NOUN
dti-1338	51	52	(	(	PUNCT
dti-1338	51	53	α	α	NOUN
dti-1338	51	54	-	-	PUNCT
dti-1338	51	55	mem	mem	ADJ
dti-1338	51	56	,	,	PUNCT
dti-1338	51	57	invitrogen	invitrogen	PROPN
dti-1338	51	58	)	)	PUNCT
dti-1338	51	59	containing	contain	VERB
dti-1338	51	60	10	10	NUM
dti-1338	51	61	%	%	NOUN
dti-1338	51	62	fbs	fb	NOUN
dti-1338	51	63	and	and	CCONJ
dti-1338	51	64	antibiotics	antibiotic	NOUN
dti-1338	51	65	,	,	PUNCT
dti-1338	51	66	supplemented	supplement	VERB
dti-1338	51	67	with	with	ADP
dti-1338	51	68	50	50	NUM
dti-1338	51	69	ug	ug	ADP
dti-1338	51	70	/	/	SYM
dti-1338	51	71	ml	ml	NOUN
dti-1338	51	72	ascorbic	ascorbic	NOUN
dti-1338	51	73	acid	acid	NOUN
dti-1338	51	74	2	2	NUM
dti-1338	51	75	-	-	PUNCT
dti-1338	51	76	phospahte	phospahte	ADJ
dti-1338	51	77	(	(	PUNCT
dti-1338	51	78	sigma	sigma	PROPN
dti-1338	51	79	,	,	PUNCT
dti-1338	51	80	st	st	PROPN
dti-1338	51	81	.	.	PROPN
dti-1338	51	82	louis	louis	PROPN
dti-1338	51	83	,	,	PUNCT
dti-1338	51	84	mo	mo	PROPN
dti-1338	51	85	,	,	PUNCT
dti-1338	51	86	usa	usa	PROPN
dti-1338	51	87	)	)	PUNCT
dti-1338	51	88	and	and	CCONJ
dti-1338	51	89	0.1	0.1	NUM
dti-1338	51	90	µm	µm	ADP
dti-1338	51	91	dexamethasone	dexamethasone	NOUN
dti-1338	51	92	.	.	PUNCT
dti-1338	52	1	after	after	ADP
dti-1338	52	2	a	a	DET
dti-1338	52	3	one	one	NUM
dti-1338	52	4	-	-	PUNCT
dti-1338	52	5	week	week	NOUN
dti-1338	52	6	culture	culture	NOUN
dti-1338	52	7	,	,	PUNCT
dti-1338	52	8	total	total	ADJ
dti-1338	52	9	rna	rna	NOUN
dti-1338	52	10	was	be	AUX
dti-1338	52	11	isolated	isolate	VERB
dti-1338	52	12	from	from	ADP
dti-1338	52	13	cultured	cultured	ADJ
dti-1338	52	14	cells	cell	NOUN
dti-1338	52	15	using	use	VERB
dti-1338	52	16	an	an	DET
dti-1338	52	17	rneasy	rneasy	NOUN
dti-1338	52	18	mini	mini	NOUN
dti-1338	52	19	kit	kit	NOUN
dti-1338	52	20	(	(	PUNCT
dti-1338	52	21	qiagen	qiagen	PROPN
dti-1338	52	22	,	,	PUNCT
dti-1338	52	23	inc	inc	PROPN
dti-1338	52	24	.	.	PROPN
dti-1338	52	25	,	,	PUNCT
dti-1338	52	26	valencia	valencia	PROPN
dti-1338	52	27	,	,	PUNCT
dti-1338	52	28	ca	ca	PROPN
dti-1338	52	29	,	,	PUNCT
dti-1338	52	30	usa	usa	PROPN
dti-1338	52	31	)	)	PUNCT
dti-1338	52	32	,	,	PUNCT
dti-1338	52	33	according	accord	VERB
dti-1338	52	34	to	to	ADP
dti-1338	52	35	the	the	DET
dti-1338	52	36	manufacturer	manufacturer	NOUN
dti-1338	52	37	’s	’s	PART
dti-1338	52	38	instructions	instruction	NOUN
dti-1338	52	39	.	.	PUNCT
dti-1338	53	1	one	one	NUM
dti-1338	53	2	-	-	PUNCT
dti-1338	53	3	step	step	NOUN
dti-1338	53	4	rt	rt	NOUN
dti-1338	53	5	-	-	PUNCT
dti-1338	53	6	pcr	pcr	NOUN
dti-1338	53	7	was	be	AUX
dti-1338	53	8	performed	perform	VERB
dti-1338	53	9	using	use	VERB
dti-1338	53	10	a	a	DET
dti-1338	53	11	superscript	superscript	ADJ
dti-1338	53	12	one	one	NUM
dti-1338	53	13	-	-	PUNCT
dti-1338	53	14	step	step	NOUN
dti-1338	53	15	rt	rt	NOUN
dti-1338	53	16	-	-	PUNCT
dti-1338	53	17	pcr	pcr	PROPN
dti-1338	53	18	with	with	ADP
dti-1338	53	19	a	a	DET
dti-1338	53	20	platinum	platinum	NOUN
dti-1338	53	21	taq	taq	NOUN
dti-1338	53	22	kit	kit	NOUN
dti-1338	53	23	(	(	PUNCT
dti-1338	53	24	invitrogen	invitrogen	PROPN
dti-1338	53	25	corporation	corporation	PROPN
dti-1338	53	26	,	,	PUNCT
dti-1338	53	27	carlsbad	carlsbad	PROPN
dti-1338	53	28	,	,	PUNCT
dti-1338	53	29	ca	ca	PROPN
dti-1338	53	30	,	,	PUNCT
dti-1338	53	31	usa	usa	PROPN
dti-1338	53	32	)	)	PUNCT
dti-1338	53	33	according	accord	VERB
dti-1338	53	34	to	to	ADP
dti-1338	53	35	the	the	DET
dti-1338	53	36	manufacturer	manufacturer	NOUN
dti-1338	53	37	’s	’s	PART
dti-1338	53	38	instructions	instruction	NOUN
dti-1338	53	39	,	,	PUNCT
dti-1338	53	40	and	and	CCONJ
dti-1338	53	41	a	a	DET
dti-1338	53	42	programmable	programmable	ADJ
dti-1338	53	43	thermal	thermal	ADJ
dti-1338	53	44	controller	controller	NOUN
dti-1338	53	45	ptc-100	ptc-100	NOUN
dti-1338	53	46	(	(	PUNCT
dti-1338	53	47	mj	mj	NOUN
dti-1338	53	48	research	research	PROPN
dti-1338	53	49	,	,	PUNCT
dti-1338	53	50	watertown	watertown	PROPN
dti-1338	53	51	,	,	PUNCT
dti-1338	53	52	ma	ma	PROPN
dti-1338	53	53	,	,	PUNCT
dti-1338	53	54	usa	usa	PROPN
dti-1338	53	55	)	)	PUNCT
dti-1338	53	56	.	.	PUNCT
dti-1338	54	1	to	to	PART
dti-1338	54	2	quantify	quantify	VERB
dti-1338	54	3	the	the	DET
dti-1338	54	4	gene	gene	NOUN
dti-1338	54	5	expression	expression	NOUN
dti-1338	54	6	of	of	ADP
dti-1338	54	7	collagen	collagen	NOUN
dti-1338	54	8	type	type	NOUN
dti-1338	54	9	i	i	PRON
dti-1338	54	10	alpha	alpha	VERB
dti-1338	54	11	2	2	NUM
dti-1338	54	12	(	(	PUNCT
dti-1338	54	13	collagen	collagen	NOUN
dti-1338	54	14	1α2	1α2	NUM
dti-1338	54	15	)	)	PUNCT
dti-1338	54	16	and	and	CCONJ
dti-1338	54	17	non	non	ADJ
dti-1338	54	18	-	-	ADJ
dti-1338	54	19	collagenous	collagenous	ADJ
dti-1338	54	20	bone	bone	NOUN
dti-1338	54	21	proteins	protein	NOUN
dti-1338	54	22	(	(	PUNCT
dti-1338	54	23	osteopontin	osteopontin	NOUN
dti-1338	54	24	,	,	PUNCT
dti-1338	54	25	osteocalcin	osteocalcin	NOUN
dti-1338	54	26	and	and	CCONJ
dti-1338	54	27	bone	bone	NOUN
dti-1338	54	28	sialoprotein	sialoprotein	NOUN
dti-1338	54	29	(	(	PUNCT
dti-1338	54	30	bsp	bsp	NOUN
dti-1338	54	31	)	)	PUNCT
dti-1338	54	32	)	)	PUNCT
dti-1338	54	33	,	,	PUNCT
dti-1338	54	34	semiquantitative	semiquantitative	ADJ
dti-1338	54	35	rt	rt	NOUN
dti-1338	54	36	-	-	PUNCT
dti-1338	54	37	pcr	pcr	ADJ
dti-1338	54	38	,	,	PUNCT
dti-1338	54	39	relative	relative	ADJ
dti-1338	54	40	to	to	ADP
dti-1338	54	41	glyceraldehyde-3	glyceraldehyde-3	VERB
dti-1338	54	42	-	-	PUNCT
dti-1338	54	43	phosphate	phosphate	ADJ
dti-1338	54	44	dehydrogenase	dehydrogenase	NOUN
dti-1338	54	45	(	(	PUNCT
dti-1338	54	46	gapdh	gapdh	NOUN
dti-1338	54	47	)	)	PUNCT
dti-1338	54	48	,	,	PUNCT
dti-1338	54	49	was	be	AUX
dti-1338	54	50	performed	perform	VERB
dti-1338	54	51	.	.	PUNCT
dti-1338	55	1	amplimers	amplimer	NOUN
dti-1338	55	2	designed	design	VERB
dti-1338	55	3	for	for	ADP
dti-1338	55	4	these	these	DET
dti-1338	55	5	four	four	NUM
dti-1338	55	6	molecules	molecule	NOUN
dti-1338	55	7	were	be	AUX
dti-1338	55	8	previously	previously	ADV
dti-1338	55	9	reported.14,15	reported.14,15	VERB
dti-1338	55	10	the	the	DET
dti-1338	55	11	pcr	pcr	ADJ
dti-1338	55	12	products	product	NOUN
dti-1338	55	13	were	be	AUX
dti-1338	55	14	subjected	subject	VERB
dti-1338	55	15	to	to	ADP
dti-1338	55	16	electrophoresis	electrophoresis	NOUN
dti-1338	55	17	,	,	PUNCT
dti-1338	55	18	and	and	CCONJ
dti-1338	55	19	digital	digital	ADJ
dti-1338	55	20	images	image	NOUN
dti-1338	55	21	were	be	AUX
dti-1338	55	22	obtained	obtain	VERB
dti-1338	55	23	and	and	CCONJ
dti-1338	55	24	analyzed	analyze	VERB
dti-1338	55	25	using	use	VERB
dti-1338	55	26	image	image	NOUN
dti-1338	55	27	j	j	PROPN
dti-1338	55	28	(	(	PUNCT
dti-1338	55	29	nih	nih	PROPN
dti-1338	55	30	image	image	NOUN
dti-1338	55	31	)	)	PUNCT
dti-1338	55	32	software	software	NOUN
dti-1338	55	33	.	.	PUNCT
dti-1338	56	1	three	three	NUM
dti-1338	56	2	populations	population	NOUN
dti-1338	56	3	of	of	ADP
dti-1338	56	4	each	each	DET
dti-1338	56	5	cell	cell	NOUN
dti-1338	56	6	type	type	NOUN
dti-1338	56	7	were	be	AUX
dti-1338	56	8	studied	study	VERB
dti-1338	56	9	.	.	PUNCT
dti-1338	57	1	statistical	statistical	ADJ
dti-1338	57	2	analyses	analysis	NOUN
dti-1338	57	3	all	all	DET
dti-1338	57	4	data	datum	NOUN
dti-1338	57	5	are	be	AUX
dti-1338	57	6	expressed	express	VERB
dti-1338	57	7	as	as	ADP
dti-1338	57	8	the	the	DET
dti-1338	57	9	mean	mean	PROPN
dti-1338	57	10	±	±	NUM
dti-1338	57	11	standard	standard	ADJ
dti-1338	57	12	deviation	deviation	NOUN
dti-1338	57	13	(	(	PUNCT
dti-1338	57	14	sd	sd	NOUN
dti-1338	57	15	)	)	PUNCT
dti-1338	57	16	.	.	PUNCT
dti-1338	58	1	statistical	statistical	ADJ
dti-1338	58	2	significance	significance	NOUN
dti-1338	58	3	was	be	AUX
dti-1338	58	4	determined	determine	VERB
dti-1338	58	5	using	use	VERB
dti-1338	58	6	one	one	NUM
dti-1338	58	7	-	-	PUNCT
dti-1338	58	8	way	way	NOUN
dti-1338	58	9	analysis	analysis	NOUN
dti-1338	58	10	of	of	ADP
dti-1338	58	11	variance	variance	NOUN
dti-1338	58	12	(	(	PUNCT
dti-1338	58	13	anova	anova	PROPN
dti-1338	58	14	)	)	PUNCT
dti-1338	58	15	followed	follow	VERB
dti-1338	58	16	by	by	ADP
dti-1338	58	17	post	post	ADJ
dti-1338	58	18	-	-	ADJ
dti-1338	58	19	hoc	hoc	ADJ
dti-1338	58	20	t	t	NOUN
dti-1338	58	21	-	-	PUNCT
dti-1338	58	22	test	test	NOUN
dti-1338	58	23	.	.	PUNCT
dti-1338	59	1	differences	difference	NOUN
dti-1338	59	2	were	be	AUX
dti-1338	59	3	considered	consider	VERB
dti-1338	59	4	significant	significant	ADJ
dti-1338	59	5	at	at	ADP
dti-1338	59	6	a	a	DET
dti-1338	59	7	p	p	NOUN
dti-1338	59	8	value	value	NOUN
dti-1338	59	9	,	,	PUNCT
dti-1338	59	10	0.05	0.05	NUM
dti-1338	59	11	.	.	PUNCT
dti-1338	60	1	results	result	NOUN
dti-1338	60	2	cell	cell	NOUN
dti-1338	60	3	morphology	morphology	NOUN
dti-1338	60	4	to	to	PART
dti-1338	60	5	examine	examine	VERB
dti-1338	60	6	the	the	DET
dti-1338	60	7	morphometric	morphometric	ADJ
dti-1338	60	8	alteration	alteration	NOUN
dti-1338	60	9	of	of	ADP
dti-1338	60	10	mesenchymal	mesenchymal	NOUN
dti-1338	60	11	cells	cell	NOUN
dti-1338	60	12	and	and	CCONJ
dti-1338	60	13	their	their	PRON
dti-1338	60	14	cytoskeleton	cytoskeleton	NOUN
dti-1338	60	15	in	in	ADP
dti-1338	60	16	the	the	DET
dti-1338	60	17	presence	presence	NOUN
dti-1338	60	18	of	of	ADP
dti-1338	60	19	vpa	vpa	PROPN
dti-1338	60	20	,	,	PUNCT
dti-1338	60	21	we	we	PRON
dti-1338	60	22	observed	observe	VERB
dti-1338	60	23	the	the	DET
dti-1338	60	24	f	f	NOUN
dti-1338	60	25	-	-	PUNCT
dti-1338	60	26	actin	actin	NOUN
dti-1338	60	27	-	-	PUNCT
dti-1338	60	28	stained	stain	VERB
dti-1338	60	29	cytoskeleton	cytoskeleton	NOUN
dti-1338	60	30	content	content	NOUN
dti-1338	60	31	at	at	ADP
dti-1338	60	32	various	various	ADJ
dti-1338	60	33	concentrations	concentration	NOUN
dti-1338	60	34	of	of	ADP
dti-1338	60	35	vpa	vpa	PROPN
dti-1338	60	36	after	after	ADP
dti-1338	60	37	a	a	DET
dti-1338	60	38	48	48	NUM
dti-1338	60	39	-	-	PUNCT
dti-1338	60	40	hour	hour	NOUN
dti-1338	60	41	culture	culture	NOUN
dti-1338	60	42	period	period	NOUN
dti-1338	60	43	.	.	PUNCT
dti-1338	61	1	both	both	PRON
dti-1338	61	2	in	in	ADP
dti-1338	61	3	the	the	DET
dti-1338	61	4	absence	absence	NOUN
dti-1338	61	5	and	and	CCONJ
dti-1338	61	6	presence	presence	NOUN
dti-1338	61	7	of	of	ADP
dti-1338	61	8	vpa	vpa	PROPN
dti-1338	61	9	,	,	PUNCT
dti-1338	61	10	mesenchymal	mesenchymal	NOUN
dti-1338	61	11	cells	cell	NOUN
dti-1338	61	12	showed	show	VERB
dti-1338	61	13	a	a	DET
dti-1338	61	14	flattened	flatten	VERB
dti-1338	61	15	and	and	CCONJ
dti-1338	61	16	extended	extended	ADJ
dti-1338	61	17	shape	shape	NOUN
dti-1338	61	18	(	(	PUNCT
dti-1338	61	19	fig	fig	NOUN
dti-1338	61	20	.	.	PUNCT
dti-1338	61	21	1	1	NUM
dti-1338	61	22	)	)	PUNCT
dti-1338	61	23	.	.	PUNCT
dti-1338	62	1	this	this	DET
dti-1338	62	2	cell	cell	NOUN
dti-1338	62	3	shape	shape	NOUN
dti-1338	62	4	was	be	AUX
dti-1338	62	5	not	not	PART
dti-1338	62	6	clearly	clearly	ADV
dti-1338	62	7	altered	alter	VERB
dti-1338	62	8	even	even	ADV
dti-1338	62	9	at	at	ADP
dti-1338	62	10	a	a	DET
dti-1338	62	11	high	high	ADJ
dti-1338	62	12	concentration	concentration	NOUN
dti-1338	62	13	of	of	ADP
dti-1338	62	14	vpa	vpa	PROPN
dti-1338	62	15	,	,	PUNCT
dti-1338	62	16	but	but	CCONJ
dti-1338	62	17	a	a	DET
dti-1338	62	18	high	high	ADJ
dti-1338	62	19	f	f	NOUN
dti-1338	62	20	-	-	PUNCT
dti-1338	62	21	actin	actin	NOUN
dti-1338	62	22	stained	stain	VERB
dti-1338	62	23	cytoskeleton	cytoskeleton	NOUN
dti-1338	62	24	content	content	NOUN
dti-1338	62	25	was	be	AUX
dti-1338	62	26	observed	observe	VERB
dti-1338	62	27	in	in	ADP
dti-1338	62	28	the	the	DET
dti-1338	62	29	cells	cell	NOUN
dti-1338	62	30	(	(	PUNCT
dti-1338	62	31	fig	fig	NOUN
dti-1338	62	32	.	.	PUNCT
dti-1338	63	1	1d	1d	NUM
dti-1338	63	2	)	)	PUNCT
dti-1338	63	3	.	.	PUNCT
dti-1338	64	1	this	this	DET
dti-1338	64	2	data	data	NOUN
dti-1338	64	3	suggests	suggest	VERB
dti-1338	64	4	that	that	SCONJ
dti-1338	64	5	vpa	vpa	PROPN
dti-1338	64	6	was	be	AUX
dti-1338	64	7	able	able	ADJ
dti-1338	64	8	to	to	PART
dti-1338	64	9	maintain	maintain	VERB
dti-1338	64	10	normal	normal	ADJ
dti-1338	64	11	cell	cell	NOUN
dti-1338	64	12	shape	shape	NOUN
dti-1338	64	13	but	but	CCONJ
dti-1338	64	14	also	also	ADV
dti-1338	64	15	synthesized	synthesize	VERB
dti-1338	64	16	a	a	DET
dti-1338	64	17	large	large	ADJ
dti-1338	64	18	number	number	NOUN
dti-1338	64	19	of	of	ADP
dti-1338	64	20	stress	stress	ADJ
dti-1338	64	21	fibers	fiber	NOUN
dti-1338	64	22	in	in	ADP
dti-1338	64	23	cells	cell	NOUN
dti-1338	64	24	at	at	ADP
dti-1338	64	25	high	high	ADJ
dti-1338	64	26	concentrations	concentration	NOUN
dti-1338	64	27	.	.	PUNCT
dti-1338	65	1	cell	cell	NOUN
dti-1338	65	2	proliferation	proliferation	NOUN
dti-1338	65	3	activity	activity	NOUN
dti-1338	65	4	to	to	PART
dti-1338	65	5	analyze	analyze	VERB
dti-1338	65	6	mesenchymal	mesenchymal	ADJ
dti-1338	65	7	cell	cell	NOUN
dti-1338	65	8	proliferation	proliferation	NOUN
dti-1338	65	9	activity	activity	NOUN
dti-1338	65	10	when	when	SCONJ
dti-1338	65	11	cells	cell	NOUN
dti-1338	65	12	were	be	AUX
dti-1338	65	13	cultured	cultured	ADJ
dti-1338	65	14	in	in	ADP
dti-1338	65	15	vpa	vpa	PROPN
dti-1338	65	16	,	,	PUNCT
dti-1338	65	17	we	we	PRON
dti-1338	65	18	cultured	cultured	ADJ
dti-1338	65	19	cells	cell	NOUN
dti-1338	65	20	http://www.la-press.com	http://www.la-press.com	X
dti-1338	65	21	hatakeyama	hatakeyama	PROPN
dti-1338	65	22	et	et	PROPN
dti-1338	65	23	al	al	PROPN
dti-1338	65	24	4	4	NUM
dti-1338	65	25	drug	drug	NOUN
dti-1338	65	26	target	target	NOUN
dti-1338	65	27	insights	insight	NOUN
dti-1338	65	28	2011:5	2011:5	NUM
dti-1338	65	29	at	at	ADP
dti-1338	65	30	various	various	ADJ
dti-1338	65	31	concentrations	concentration	NOUN
dti-1338	65	32	,	,	PUNCT
dti-1338	65	33	from	from	ADP
dti-1338	65	34	10	10	NUM
dti-1338	65	35	to	to	PART
dti-1338	65	36	1000	1000	NUM
dti-1338	65	37	µg	µg	NOUN
dti-1338	65	38	/	/	SYM
dti-1338	65	39	ml	ml	NOUN
dti-1338	65	40	,	,	PUNCT
dti-1338	65	41	because	because	SCONJ
dti-1338	65	42	therapeutic	therapeutic	ADJ
dti-1338	65	43	levels	level	NOUN
dti-1338	65	44	appear	appear	VERB
dti-1338	65	45	to	to	PART
dti-1338	65	46	range	range	VERB
dti-1338	65	47	from	from	ADP
dti-1338	65	48	50	50	NUM
dti-1338	65	49	to	to	PART
dti-1338	65	50	100	100	NUM
dti-1338	65	51	µg	µg	ADV
dti-1338	65	52	/	/	SYM
dti-1338	65	53	ml	ml	NOUN
dti-1338	65	54	in	in	ADP
dti-1338	65	55	human	human	ADJ
dti-1338	65	56	serum	serum	NOUN
dti-1338	65	57	,	,	PUNCT
dti-1338	65	58	and	and	CCONJ
dti-1338	65	59	also	also	ADV
dti-1338	65	60	because	because	SCONJ
dti-1338	65	61	we	we	PRON
dti-1338	65	62	had	have	AUX
dti-1338	65	63	already	already	ADV
dti-1338	65	64	reported	report	VERB
dti-1338	65	65	that	that	SCONJ
dti-1338	65	66	a	a	DET
dti-1338	65	67	vpa	vpa	PROPN
dti-1338	65	68	concentration	concentration	NOUN
dti-1338	65	69	of	of	ADP
dti-1338	65	70	1000	1000	NUM
dti-1338	65	71	µg	µg	NOUN
dti-1338	65	72	/	/	SYM
dti-1338	65	73	ml	ml	NOUN
dti-1338	65	74	affects	affect	NOUN
dti-1338	65	75	bone	bone	NOUN
dti-1338	65	76	resorption	resorption	NOUN
dti-1338	65	77	in	in	ADP
dti-1338	65	78	rat	rat	NOUN
dti-1338	65	79	calvaria	calvaria	NOUN
dti-1338	65	80	organ	organ	VERB
dti-1338	65	81	culture.16	culture.16	PROPN
dti-1338	65	82	the	the	DET
dti-1338	65	83	c3h10t1/2	c3h10t1/2	PROPN
dti-1338	65	84	mouse	mouse	NOUN
dti-1338	65	85	mesenchymal	mesenchymal	NOUN
dti-1338	65	86	cell	cell	NOUN
dti-1338	65	87	line	line	NOUN
dti-1338	65	88	was	be	AUX
dti-1338	65	89	cultured	cultured	ADJ
dti-1338	65	90	in	in	ADP
dti-1338	65	91	the	the	DET
dti-1338	65	92	absence	absence	NOUN
dti-1338	65	93	(	(	PUNCT
dti-1338	65	94	0	0	NUM
dti-1338	65	95	µg	µg	NOUN
dti-1338	65	96	/	/	SYM
dti-1338	65	97	ml	ml	NOUN
dti-1338	65	98	)	)	PUNCT
dti-1338	65	99	or	or	CCONJ
dti-1338	65	100	presence	presence	NOUN
dti-1338	65	101	of	of	ADP
dti-1338	65	102	various	various	ADJ
dti-1338	65	103	concentrations	concentration	NOUN
dti-1338	65	104	of	of	ADP
dti-1338	65	105	vpa	vpa	PROPN
dti-1338	65	106	(	(	PUNCT
dti-1338	65	107	10	10	NUM
dti-1338	65	108	,	,	PUNCT
dti-1338	65	109	100	100	NUM
dti-1338	65	110	,	,	PUNCT
dti-1338	65	111	1000	1000	NUM
dti-1338	65	112	µg	µg	NOUN
dti-1338	65	113	/	/	SYM
dti-1338	65	114	ml	ml	NOUN
dti-1338	65	115	)	)	PUNCT
dti-1338	65	116	for	for	ADP
dti-1338	65	117	48	48	NUM
dti-1338	65	118	hours	hour	NOUN
dti-1338	65	119	on	on	ADP
dti-1338	65	120	a	a	DET
dti-1338	65	121	non	non	ADJ
dti-1338	65	122	-	-	ADJ
dti-1338	65	123	coated	coated	ADJ
dti-1338	65	124	plastic	plastic	NOUN
dti-1338	65	125	cell	cell	NOUN
dti-1338	65	126	culture	culture	NOUN
dti-1338	65	127	plate	plate	NOUN
dti-1338	65	128	(	(	PUNCT
dti-1338	65	129	fig	fig	NOUN
dti-1338	65	130	.	.	PUNCT
dti-1338	66	1	2a	2a	NUM
dti-1338	66	2	–	–	PUNCT
dti-1338	66	3	d	d	NOUN
dti-1338	66	4	)	)	PUNCT
dti-1338	66	5	.	.	PUNCT
dti-1338	67	1	after	after	ADP
dti-1338	67	2	the	the	DET
dti-1338	67	3	cell	cell	NOUN
dti-1338	67	4	culture	culture	NOUN
dti-1338	67	5	period	period	NOUN
dti-1338	67	6	,	,	PUNCT
dti-1338	67	7	cell	cell	NOUN
dti-1338	67	8	proliferation	proliferation	NOUN
dti-1338	67	9	activity	activity	NOUN
dti-1338	67	10	was	be	AUX
dti-1338	67	11	detected	detect	VERB
dti-1338	67	12	by	by	ADP
dti-1338	67	13	pcna	pcna	NOUN
dti-1338	67	14	staining	stain	VERB
dti-1338	67	15	.	.	PUNCT
dti-1338	68	1	pcna	pcna	NOUN
dti-1338	68	2	-	-	PUNCT
dti-1338	68	3	negative	negative	ADJ
dti-1338	68	4	cells	cell	NOUN
dti-1338	68	5	were	be	AUX
dti-1338	68	6	counterstained	counterstaine	VERB
dti-1338	68	7	by	by	ADP
dti-1338	68	8	hematoxylin	hematoxylin	PROPN
dti-1338	68	9	.	.	PUNCT
dti-1338	69	1	at	at	ADP
dti-1338	69	2	all	all	DET
dti-1338	69	3	vpa	vpa	PROPN
dti-1338	69	4	concentrations	concentration	NOUN
dti-1338	69	5	from	from	ADP
dti-1338	69	6	10	10	NUM
dti-1338	69	7	to	to	PART
dti-1338	69	8	1000	1000	NUM
dti-1338	69	9	µg	µg	NOUN
dti-1338	69	10	/	/	SYM
dti-1338	69	11	ml	ml	NOUN
dti-1338	69	12	,	,	PUNCT
dti-1338	69	13	cells	cell	NOUN
dti-1338	69	14	were	be	AUX
dti-1338	69	15	attached	attach	VERB
dti-1338	69	16	to	to	ADP
dti-1338	69	17	a	a	DET
dti-1338	69	18	non	non	ADJ
dti-1338	69	19	-	-	ADJ
dti-1338	69	20	coated	coated	ADJ
dti-1338	69	21	plastic	plastic	NOUN
dti-1338	69	22	cell	cell	NOUN
dti-1338	69	23	culture	culture	NOUN
dti-1338	69	24	plate	plate	NOUN
dti-1338	69	25	and	and	CCONJ
dti-1338	69	26	pcna	pcna	NOUN
dti-1338	69	27	-	-	PUNCT
dti-1338	69	28	positive	positive	ADJ
dti-1338	69	29	cells	cell	NOUN
dti-1338	69	30	were	be	AUX
dti-1338	69	31	observed	observe	VERB
dti-1338	69	32	at	at	ADP
dti-1338	69	33	all	all	DET
dti-1338	69	34	vpa	vpa	PROPN
dti-1338	69	35	concentrations	concentration	NOUN
dti-1338	69	36	(	(	PUNCT
dti-1338	69	37	fig	fig	NOUN
dti-1338	69	38	.	.	PUNCT
dti-1338	70	1	2a	2a	NUM
dti-1338	70	2	–	–	PUNCT
dti-1338	70	3	d	d	NOUN
dti-1338	70	4	)	)	PUNCT
dti-1338	70	5	.	.	PUNCT
dti-1338	71	1	when	when	SCONJ
dti-1338	71	2	pcna	pcna	NOUN
dti-1338	71	3	-	-	PUNCT
dti-1338	71	4	positive	positive	ADJ
dti-1338	71	5	cell	cell	NOUN
dti-1338	71	6	counts	count	NOUN
dti-1338	71	7	were	be	AUX
dti-1338	71	8	obtained	obtain	VERB
dti-1338	71	9	from	from	ADP
dti-1338	71	10	five	five	NUM
dti-1338	71	11	randomly	randomly	ADV
dti-1338	71	12	chosen	choose	VERB
dti-1338	71	13	areas	area	NOUN
dti-1338	71	14	following	follow	VERB
dti-1338	71	15	the	the	DET
dti-1338	71	16	48	48	NUM
dti-1338	71	17	-	-	PUNCT
dti-1338	71	18	hour	hour	NOUN
dti-1338	71	19	culture	culture	NOUN
dti-1338	71	20	,	,	PUNCT
dti-1338	71	21	the	the	DET
dti-1338	71	22	cell	cell	NOUN
dti-1338	71	23	number	number	NOUN
dti-1338	71	24	decreased	decrease	VERB
dti-1338	71	25	significantly	significantly	ADV
dti-1338	71	26	only	only	ADV
dti-1338	71	27	at	at	ADP
dti-1338	71	28	a	a	DET
dti-1338	71	29	vpa	vpa	PROPN
dti-1338	71	30	concentration	concentration	NOUN
dti-1338	71	31	of	of	ADP
dti-1338	71	32	1000	1000	NUM
dti-1338	71	33	µg	µg	NOUN
dti-1338	71	34	/	/	SYM
dti-1338	71	35	ml	ml	NOUN
dti-1338	71	36	and	and	CCONJ
dti-1338	71	37	there	there	PRON
dti-1338	71	38	was	be	VERB
dti-1338	71	39	no	no	DET
dti-1338	71	40	difference	difference	NOUN
dti-1338	71	41	noted	note	VERB
dti-1338	71	42	at	at	ADP
dti-1338	71	43	other	other	ADJ
dti-1338	71	44	concentrations	concentration	NOUN
dti-1338	71	45	(	(	PUNCT
dti-1338	71	46	fig	fig	NOUN
dti-1338	71	47	.	.	PUNCT
dti-1338	72	1	2e	2e	NUM
dti-1338	72	2	)	)	PUNCT
dti-1338	72	3	.	.	PUNCT
dti-1338	73	1	these	these	DET
dti-1338	73	2	data	datum	NOUN
dti-1338	73	3	indicate	indicate	VERB
dti-1338	73	4	that	that	SCONJ
dti-1338	73	5	vpa	vpa	PROPN
dti-1338	73	6	had	have	VERB
dti-1338	73	7	no	no	DET
dti-1338	73	8	effect	effect	NOUN
dti-1338	73	9	on	on	ADP
dti-1338	73	10	mesenchymal	mesenchymal	ADJ
dti-1338	73	11	cell	cell	NOUN
dti-1338	73	12	proliferation	proliferation	NOUN
dti-1338	73	13	when	when	SCONJ
dti-1338	73	14	cells	cell	NOUN
dti-1338	73	15	were	be	AUX
dti-1338	73	16	cultured	cultured	ADJ
dti-1338	73	17	on	on	ADP
dti-1338	73	18	a	a	DET
dti-1338	73	19	non	non	ADJ
dti-1338	73	20	-	-	ADJ
dti-1338	73	21	coated	coated	ADJ
dti-1338	73	22	plastic	plastic	NOUN
dti-1338	73	23	plate	plate	NOUN
dti-1338	73	24	.	.	PUNCT
dti-1338	74	1	a	a	DET
dti-1338	74	2	b	b	X
dti-1338	74	3	c	c	NOUN
dti-1338	74	4	d	d	NOUN
dti-1338	74	5	0	0	NUM
dti-1338	74	6	µg	µg	NOUN
dti-1338	74	7	/	/	SYM
dti-1338	74	8	ml	ml	PROPN
dti-1338	74	9	10	10	NUM
dti-1338	74	10	µg	µg	NOUN
dti-1338	74	11	/	/	SYM
dti-1338	74	12	ml	ml	NOUN
dti-1338	74	13	100	100	NUM
dti-1338	74	14	µg	µg	ADJ
dti-1338	74	15	/	/	SYM
dti-1338	74	16	ml	ml	PROPN
dti-1338	74	17	1000	1000	NUM
dti-1338	74	18	µg	µg	NOUN
dti-1338	74	19	/	/	SYM
dti-1338	74	20	ml	ml	NOUN
dti-1338	74	21	figure	figure	NOUN
dti-1338	74	22	1	1	NUM
dti-1338	74	23	.	.	PUNCT
dti-1338	75	1	vpa	vpa	PROPN
dti-1338	75	2	does	do	AUX
dti-1338	75	3	not	not	PART
dti-1338	75	4	alter	alter	VERB
dti-1338	75	5	mesenchymal	mesenchymal	ADJ
dti-1338	75	6	cell	cell	NOUN
dti-1338	75	7	shape	shape	NOUN
dti-1338	75	8	even	even	ADV
dti-1338	75	9	in	in	ADP
dti-1338	75	10	high	high	ADJ
dti-1338	75	11	concentrations	concentration	NOUN
dti-1338	75	12	.	.	PUNCT
dti-1338	76	1	mesenchymal	mesenchymal	ADJ
dti-1338	76	2	cells	cell	NOUN
dti-1338	76	3	were	be	AUX
dti-1338	76	4	cultured	cultured	ADJ
dti-1338	76	5	in	in	ADP
dti-1338	76	6	the	the	DET
dti-1338	76	7	absence	absence	NOUN
dti-1338	76	8	(	(	PUNCT
dti-1338	76	9	0	0	NUM
dti-1338	76	10	µg	µg	NOUN
dti-1338	76	11	/	/	SYM
dti-1338	76	12	ml	ml	NOUN
dti-1338	76	13	,	,	PUNCT
dti-1338	76	14	a	a	NOUN
dti-1338	76	15	)	)	PUNCT
dti-1338	76	16	or	or	CCONJ
dti-1338	76	17	presence	presence	NOUN
dti-1338	76	18	of	of	ADP
dti-1338	76	19	vpa	vpa	PROPN
dti-1338	76	20	at	at	ADP
dti-1338	76	21	various	various	ADJ
dti-1338	76	22	concentration	concentration	NOUN
dti-1338	76	23	(	(	PUNCT
dti-1338	76	24	10	10	NUM
dti-1338	76	25	µg	µg	NOUN
dti-1338	76	26	/	/	SYM
dti-1338	76	27	ml	ml	PROPN
dti-1338	76	28	,	,	PUNCT
dti-1338	76	29	b.	b.	PROPN
dti-1338	76	30	,	,	PUNCT
dti-1338	76	31	100	100	NUM
dti-1338	76	32	µg	µg	ADJ
dti-1338	76	33	/	/	SYM
dti-1338	76	34	ml	ml	NOUN
dti-1338	76	35	,	,	PUNCT
dti-1338	76	36	c.	c.	NOUN
dti-1338	76	37	,	,	PUNCT
dti-1338	76	38	and	and	CCONJ
dti-1338	76	39	1000	1000	NUM
dti-1338	76	40	µg	µg	NOUN
dti-1338	76	41	/	/	SYM
dti-1338	76	42	ml	ml	NOUN
dti-1338	76	43	d	d	NOUN
dti-1338	76	44	)	)	PUNCT
dti-1338	76	45	for	for	ADP
dti-1338	76	46	48	48	NUM
dti-1338	76	47	hours	hour	NOUN
dti-1338	76	48	.	.	PUNCT
dti-1338	77	1	cells	cell	NOUN
dti-1338	77	2	were	be	AUX
dti-1338	77	3	stained	stain	VERB
dti-1338	77	4	with	with	ADP
dti-1338	77	5	f	f	NOUN
dti-1338	77	6	-	-	PUNCT
dti-1338	77	7	actin	actin	NOUN
dti-1338	77	8	(	(	PUNCT
dti-1338	77	9	green	green	NOUN
dti-1338	77	10	)	)	PUNCT
dti-1338	77	11	and	and	CCONJ
dti-1338	77	12	nuclear	nuclear	NOUN
dti-1338	77	13	counterstained	counterstaine	VERB
dti-1338	77	14	with	with	ADP
dti-1338	77	15	dapi	dapi	ADJ
dti-1338	77	16	(	(	PUNCT
dti-1338	77	17	blue	blue	ADJ
dti-1338	77	18	)	)	PUNCT
dti-1338	77	19	.	.	PUNCT
dti-1338	78	1	both	both	PRON
dti-1338	78	2	in	in	ADP
dti-1338	78	3	the	the	DET
dti-1338	78	4	absence	absence	NOUN
dti-1338	78	5	or	or	CCONJ
dti-1338	78	6	presence	presence	NOUN
dti-1338	78	7	of	of	ADP
dti-1338	78	8	high	high	ADJ
dti-1338	78	9	concentrations	concentration	NOUN
dti-1338	78	10	of	of	ADP
dti-1338	78	11	vpa	vpa	PROPN
dti-1338	78	12	,	,	PUNCT
dti-1338	78	13	mesenchymal	mesenchymal	NOUN
dti-1338	78	14	cells	cell	NOUN
dti-1338	78	15	maintained	maintain	VERB
dti-1338	78	16	a	a	DET
dti-1338	78	17	flattened	flatten	VERB
dti-1338	78	18	and	and	CCONJ
dti-1338	78	19	extended	extended	ADJ
dti-1338	78	20	shape	shape	NOUN
dti-1338	78	21	.	.	PUNCT
dti-1338	79	1	note	note	NOUN
dti-1338	79	2	:	:	PUNCT
dti-1338	79	3	the	the	DET
dti-1338	79	4	bar	bar	NOUN
dti-1338	79	5	in	in	ADP
dti-1338	79	6	d	d	PROPN
dti-1338	79	7	represents	represent	VERB
dti-1338	79	8	50	50	NUM
dti-1338	79	9	µm	µm	NOUN
dti-1338	79	10	.	.	PUNCT
dti-1338	80	1	figure	figure	NOUN
dti-1338	80	2	2	2	NUM
dti-1338	80	3	.	.	PUNCT
dti-1338	80	4	proliferation	proliferation	NOUN
dti-1338	80	5	of	of	ADP
dti-1338	80	6	pluripotent	pluripotent	ADJ
dti-1338	80	7	mesenchymal	mesenchymal	NOUN
dti-1338	80	8	cells	cell	NOUN
dti-1338	80	9	is	be	AUX
dti-1338	80	10	inhibited	inhibit	VERB
dti-1338	80	11	by	by	ADP
dti-1338	80	12	vpa	vpa	PROPN
dti-1338	80	13	at	at	ADP
dti-1338	80	14	a	a	DET
dti-1338	80	15	high	high	ADJ
dti-1338	80	16	concentration	concentration	NOUN
dti-1338	80	17	.	.	PUNCT
dti-1338	81	1	c3h10t1/2	c3h10t1/2	PROPN
dti-1338	81	2	,	,	PUNCT
dti-1338	81	3	a	a	DET
dti-1338	81	4	mouse	mouse	NOUN
dti-1338	81	5	mesenchymal	mesenchymal	NOUN
dti-1338	81	6	cell	cell	NOUN
dti-1338	81	7	line	line	NOUN
dti-1338	81	8	,	,	PUNCT
dti-1338	81	9	was	be	AUX
dti-1338	81	10	cultured	cultured	ADJ
dti-1338	81	11	in	in	ADP
dti-1338	81	12	the	the	DET
dti-1338	81	13	absence	absence	NOUN
dti-1338	81	14	(	(	PUNCT
dti-1338	81	15	0	0	NUM
dti-1338	81	16	µg	µg	NOUN
dti-1338	81	17	/	/	SYM
dti-1338	81	18	ml	ml	NOUN
dti-1338	81	19	,	,	PUNCT
dti-1338	81	20	a	a	NOUN
dti-1338	81	21	)	)	PUNCT
dti-1338	81	22	or	or	CCONJ
dti-1338	81	23	presence	presence	NOUN
dti-1338	81	24	of	of	ADP
dti-1338	81	25	vpa	vpa	PROPN
dti-1338	81	26	at	at	ADP
dti-1338	81	27	various	various	ADJ
dti-1338	81	28	concentration	concentration	NOUN
dti-1338	81	29	(	(	PUNCT
dti-1338	81	30	10	10	NUM
dti-1338	81	31	µg	µg	NOUN
dti-1338	81	32	/	/	SYM
dti-1338	81	33	ml	ml	PROPN
dti-1338	81	34	,	,	PUNCT
dti-1338	81	35	b.	b.	PROPN
dti-1338	81	36	,	,	PUNCT
dti-1338	81	37	100	100	NUM
dti-1338	81	38	µg	µg	ADJ
dti-1338	81	39	/	/	SYM
dti-1338	81	40	ml	ml	NOUN
dti-1338	81	41	,	,	PUNCT
dti-1338	81	42	c.	c.	NOUN
dti-1338	81	43	,	,	PUNCT
dti-1338	81	44	and	and	CCONJ
dti-1338	81	45	1000	1000	NUM
dti-1338	81	46	µg	µg	NOUN
dti-1338	81	47	/	/	SYM
dti-1338	81	48	ml	ml	NOUN
dti-1338	81	49	,	,	PUNCT
dti-1338	81	50	d	d	NOUN
dti-1338	81	51	)	)	PUNCT
dti-1338	81	52	for	for	ADP
dti-1338	81	53	48	48	NUM
dti-1338	81	54	hours	hour	NOUN
dti-1338	81	55	.	.	PUNCT
dti-1338	82	1	cell	cell	NOUN
dti-1338	82	2	proliferation	proliferation	NOUN
dti-1338	82	3	activity	activity	NOUN
dti-1338	82	4	was	be	AUX
dti-1338	82	5	detected	detect	VERB
dti-1338	82	6	by	by	ADP
dti-1338	82	7	pcna	pcna	NOUN
dti-1338	82	8	staining	stain	VERB
dti-1338	82	9	following	follow	VERB
dti-1338	82	10	cell	cell	NOUN
dti-1338	82	11	culture	culture	NOUN
dti-1338	82	12	.	.	PUNCT
dti-1338	83	1	(	(	PUNCT
dti-1338	83	2	a	a	X
dti-1338	83	3	–	–	PUNCT
dti-1338	83	4	d	d	NOUN
dti-1338	83	5	)	)	PUNCT
dti-1338	83	6	pcna	pcna	NOUN
dti-1338	83	7	-	-	PUNCT
dti-1338	83	8	positive	positive	ADJ
dti-1338	83	9	cells	cell	NOUN
dti-1338	83	10	(	(	PUNCT
dti-1338	83	11	brown	brown	PROPN
dti-1338	83	12	)	)	PUNCT
dti-1338	83	13	were	be	AUX
dti-1338	83	14	present	present	ADJ
dti-1338	83	15	even	even	ADV
dti-1338	83	16	at	at	ADP
dti-1338	83	17	1000	1000	NUM
dti-1338	83	18	µg	µg	NOUN
dti-1338	83	19	/	/	SYM
dti-1338	83	20	ml	ml	NOUN
dti-1338	83	21	.	.	PUNCT
dti-1338	84	1	negative	negative	ADJ
dti-1338	84	2	cells	cell	NOUN
dti-1338	84	3	were	be	AUX
dti-1338	84	4	counterstained	counterstaine	VERB
dti-1338	84	5	by	by	ADP
dti-1338	84	6	hematoxylin	hematoxylin	PROPN
dti-1338	84	7	(	(	PUNCT
dti-1338	84	8	blue	blue	ADJ
dti-1338	84	9	)	)	PUNCT
dti-1338	84	10	.	.	PUNCT
dti-1338	85	1	e	e	X
dti-1338	85	2	)	)	PUNCT
dti-1338	85	3	both	both	PRON
dti-1338	85	4	pcna	pcna	NOUN
dti-1338	85	5	-	-	PUNCT
dti-1338	85	6	positive	positive	ADJ
dti-1338	85	7	cell	cell	NOUN
dti-1338	85	8	counts	count	NOUN
dti-1338	85	9	and	and	CCONJ
dti-1338	85	10	total	total	ADJ
dti-1338	85	11	cell	cell	NOUN
dti-1338	85	12	counts	count	NOUN
dti-1338	85	13	were	be	AUX
dti-1338	85	14	obtained	obtain	VERB
dti-1338	85	15	from	from	ADP
dti-1338	85	16	five	five	NUM
dti-1338	85	17	randomly	randomly	ADV
dti-1338	85	18	chosen	choose	VERB
dti-1338	85	19	areas	area	NOUN
dti-1338	85	20	following	follow	VERB
dti-1338	85	21	the	the	DET
dti-1338	85	22	48	48	NUM
dti-1338	85	23	-	-	PUNCT
dti-1338	85	24	hour	hour	NOUN
dti-1338	85	25	culture	culture	NOUN
dti-1338	85	26	period	period	NOUN
dti-1338	85	27	.	.	PUNCT
dti-1338	86	1	the	the	DET
dti-1338	86	2	bar	bar	NOUN
dti-1338	86	3	graph	graph	NOUN
dti-1338	86	4	expresses	express	VERB
dti-1338	86	5	the	the	DET
dti-1338	86	6	relative	relative	ADJ
dti-1338	86	7	ratios	ratio	NOUN
dti-1338	86	8	of	of	ADP
dti-1338	86	9	their	their	PRON
dti-1338	86	10	average	average	ADJ
dti-1338	86	11	values	value	NOUN
dti-1338	86	12	.	.	PUNCT
dti-1338	87	1	pcna	pcna	NOUN
dti-1338	87	2	-	-	PUNCT
dti-1338	87	3	positive	positive	ADJ
dti-1338	87	4	cell	cell	NOUN
dti-1338	87	5	numbers	number	NOUN
dti-1338	87	6	decreased	decrease	VERB
dti-1338	87	7	significantly	significantly	ADV
dti-1338	87	8	only	only	ADV
dti-1338	87	9	at	at	ADP
dti-1338	87	10	a	a	DET
dti-1338	87	11	vpa	vpa	PROPN
dti-1338	87	12	concentration	concentration	NOUN
dti-1338	87	13	of	of	ADP
dti-1338	87	14	1000	1000	NUM
dti-1338	87	15	µg	µg	NOUN
dti-1338	87	16	/	/	SYM
dti-1338	87	17	ml	ml	NOUN
dti-1338	87	18	when	when	SCONJ
dti-1338	87	19	compared	compare	VERB
dti-1338	87	20	with	with	ADP
dti-1338	87	21	the	the	DET
dti-1338	87	22	numbers	number	NOUN
dti-1338	87	23	obtained	obtain	VERB
dti-1338	87	24	from	from	ADP
dti-1338	87	25	the	the	DET
dti-1338	87	26	absence	absence	NOUN
dti-1338	87	27	of	of	ADP
dti-1338	87	28	vpa	vpa	PROPN
dti-1338	87	29	.	.	PUNCT
dti-1338	88	1	notes	note	VERB
dti-1338	88	2	:	:	PUNCT
dti-1338	88	3	*	*	PUNCT
dti-1338	88	4	p	p	NOUN
dti-1338	88	5	,	,	PUNCT
dti-1338	88	6	0.05	0.05	NUM
dti-1338	88	7	when	when	SCONJ
dti-1338	88	8	compared	compare	VERB
dti-1338	88	9	to	to	ADP
dti-1338	88	10	0	0	NUM
dti-1338	88	11	µg	µg	NOUN
dti-1338	88	12	/	/	SYM
dti-1338	88	13	ml	ml	NOUN
dti-1338	88	14	.	.	PUNCT
dti-1338	89	1	the	the	DET
dti-1338	89	2	bar	bar	NOUN
dti-1338	89	3	in	in	ADP
dti-1338	89	4	d	d	PROPN
dti-1338	89	5	represents	represent	VERB
dti-1338	89	6	200	200	NUM
dti-1338	89	7	µm	µm	NOUN
dti-1338	89	8	.	.	PUNCT
dti-1338	90	1	a	a	DET
dti-1338	90	2	0	0	NUM
dti-1338	90	3	µg	µg	NOUN
dti-1338	90	4	/	/	SYM
dti-1338	90	5	ml	ml	PROPN
dti-1338	90	6	10	10	NUM
dti-1338	90	7	µg	µg	NOUN
dti-1338	90	8	/	/	SYM
dti-1338	90	9	ml	ml	NOUN
dti-1338	90	10	100	100	NUM
dti-1338	90	11	µg	µg	ADJ
dti-1338	90	12	/	/	SYM
dti-1338	90	13	ml	ml	PROPN
dti-1338	90	14	1000	1000	NUM
dti-1338	90	15	µg	µg	NOUN
dti-1338	90	16	/	/	SYM
dti-1338	90	17	ml	ml	NOUN
dti-1338	90	18	b	b	PROPN
dti-1338	90	19	c	c	NOUN
dti-1338	90	20	d	d	X
dti-1338	90	21	*	*	PUNCT
dti-1338	90	22	0.6	0.6	NUM
dti-1338	90	23	0.5	0.5	NUM
dti-1338	90	24	0.4	0.4	NUM
dti-1338	90	25	0.3	0.3	NUM
dti-1338	90	26	0.2	0.2	NUM
dti-1338	90	27	0.1	0.1	NUM
dti-1338	90	28	0	0	NUM
dti-1338	90	29	0	0	NUM
dti-1338	90	30	10	10	NUM
dti-1338	90	31	100	100	NUM
dti-1338	90	32	1000	1000	NUM
dti-1338	90	33	p	p	NOUN
dti-1338	90	34	c	c	NOUN
dti-1338	90	35	n	n	PRON
dti-1338	90	36	a	a	DET
dti-1338	90	37	p	p	X
dti-1338	90	38	o	o	X
dti-1338	90	39	st	st	PROPN
dti-1338	90	40	iv	iv	PROPN
dti-1338	90	41	e	e	PROPN
dti-1338	90	42	ce	ce	PROPN
dti-1338	90	43	lls	ll	VERB
dti-1338	90	44	re	re	VERB
dti-1338	90	45	la	la	X
dti-1338	90	46	ti	ti	X
dti-1338	90	47	ve	ve	NOUN
dti-1338	90	48	r	r	NOUN
dti-1338	90	49	at	at	ADP
dti-1338	90	50	io	io	PROPN
dti-1338	90	51	t	t	NOUN
dti-1338	90	52	o	o	X
dti-1338	91	1	t	t	X
dti-1338	91	2	o	o	X
dti-1338	91	3	ta	ta	X
dti-1338	92	1	l	l	PROPN
dti-1338	92	2	c	c	PROPN
dti-1338	92	3	el	el	PROPN
dti-1338	92	4	ls	ls	PROPN
dti-1338	92	5	vpa	vpa	PROPN
dti-1338	92	6	concentration	concentration	NOUN
dti-1338	92	7	(	(	PUNCT
dti-1338	92	8	µg	µg	NOUN
dti-1338	92	9	/	/	SYM
dti-1338	92	10	ml	ml	NOUN
dti-1338	92	11	)	)	PUNCT
dti-1338	92	12	e	e	NOUN
dti-1338	92	13	effect	effect	NOUN
dti-1338	92	14	of	of	ADP
dti-1338	92	15	ecms	ecms	NOUN
dti-1338	92	16	on	on	ADP
dti-1338	92	17	cell	cell	NOUN
dti-1338	92	18	number	number	NOUN
dti-1338	92	19	for	for	ADP
dti-1338	92	20	quantitative	quantitative	ADJ
dti-1338	92	21	examination	examination	NOUN
dti-1338	92	22	of	of	ADP
dti-1338	92	23	the	the	DET
dti-1338	92	24	vpa	vpa	PROPN
dti-1338	92	25	effect	effect	NOUN
dti-1338	92	26	on	on	ADP
dti-1338	92	27	cell	cell	NOUN
dti-1338	92	28	proliferation	proliferation	NOUN
dti-1338	92	29	in	in	ADP
dti-1338	92	30	the	the	DET
dti-1338	92	31	presence	presence	NOUN
dti-1338	92	32	of	of	ADP
dti-1338	92	33	ecms	ecms	NOUN
dti-1338	92	34	,	,	PUNCT
dti-1338	92	35	we	we	PRON
dti-1338	92	36	performed	perform	VERB
dti-1338	92	37	a	a	DET
dti-1338	92	38	mesenchymal	mesenchymal	NOUN
dti-1338	92	39	cell	cell	NOUN
dti-1338	92	40	proliferation	proliferation	NOUN
dti-1338	92	41	assay	assay	VERB
dti-1338	92	42	using	use	VERB
dti-1338	92	43	fibronectinand	fibronectinand	NOUN
dti-1338	92	44	type	type	NOUN
dti-1338	93	1	i	i	PRON
dti-1338	93	2	collagen	collagen	NOUN
dti-1338	93	3	-	-	PUNCT
dti-1338	93	4	coated	coat	VERB
dti-1338	93	5	cell	cell	NOUN
dti-1338	93	6	culture	culture	NOUN
dti-1338	93	7	http://www.la-press.com	http://www.la-press.com	X
dti-1338	94	1	the	the	DET
dti-1338	94	2	effect	effect	NOUN
dti-1338	94	3	of	of	ADP
dti-1338	94	4	vpa	vpa	PROPN
dti-1338	94	5	on	on	ADP
dti-1338	94	6	mesenchymal	mesenchymal	ADJ
dti-1338	94	7	cell	cell	NOUN
dti-1338	94	8	in	in	ADP
dti-1338	94	9	ecm	ecm	PROPN
dti-1338	94	10	drug	drug	NOUN
dti-1338	94	11	target	target	NOUN
dti-1338	94	12	insights	insight	NOUN
dti-1338	94	13	2011:5	2011:5	NUM
dti-1338	94	14	5	5	NUM
dti-1338	94	15	plates	plate	NOUN
dti-1338	94	16	and	and	CCONJ
dti-1338	94	17	compared	compare	VERB
dti-1338	94	18	the	the	DET
dti-1338	94	19	results	result	NOUN
dti-1338	94	20	to	to	ADP
dti-1338	94	21	an	an	DET
dti-1338	94	22	assay	assay	NOUN
dti-1338	94	23	performed	perform	VERB
dti-1338	94	24	on	on	ADP
dti-1338	94	25	the	the	DET
dti-1338	94	26	cells	cell	NOUN
dti-1338	94	27	seeded	seed	VERB
dti-1338	94	28	on	on	ADP
dti-1338	94	29	a	a	DET
dti-1338	94	30	non	non	ADJ
dti-1338	94	31	-	-	ADJ
dti-1338	94	32	coated	coated	ADJ
dti-1338	94	33	plastic	plastic	NOUN
dti-1338	94	34	plate	plate	NOUN
dti-1338	94	35	.	.	PUNCT
dti-1338	95	1	cell	cell	NOUN
dti-1338	95	2	number	number	NOUN
dti-1338	95	3	on	on	ADP
dti-1338	95	4	both	both	CCONJ
dti-1338	95	5	the	the	DET
dti-1338	95	6	non	non	ADJ
dti-1338	95	7	-	-	ADJ
dti-1338	95	8	coated	coated	ADJ
dti-1338	95	9	plastic	plastic	NOUN
dti-1338	95	10	plate	plate	NOUN
dti-1338	95	11	and	and	CCONJ
dti-1338	95	12	the	the	DET
dti-1338	95	13	ecm	ecm	PROPN
dti-1338	95	14	plates	plate	NOUN
dti-1338	95	15	were	be	AUX
dti-1338	95	16	estimated	estimate	VERB
dti-1338	95	17	indirectly	indirectly	ADV
dti-1338	95	18	using	use	VERB
dti-1338	95	19	highly	highly	ADV
dti-1338	95	20	water	water	NOUN
dti-1338	95	21	-	-	PUNCT
dti-1338	95	22	soluble	soluble	ADJ
dti-1338	95	23	formazan	formazan	ADJ
dti-1338	95	24	dye	dye	NOUN
dti-1338	95	25	as	as	SCONJ
dti-1338	95	26	described	describe	VERB
dti-1338	95	27	in	in	ADP
dti-1338	95	28	the	the	DET
dti-1338	95	29	materials	material	NOUN
dti-1338	95	30	and	and	CCONJ
dti-1338	95	31	methods	method	NOUN
dti-1338	95	32	section	section	NOUN
dti-1338	95	33	.	.	PUNCT
dti-1338	96	1	on	on	ADP
dti-1338	96	2	the	the	DET
dti-1338	96	3	non	non	ADJ
dti-1338	96	4	-	-	ADJ
dti-1338	96	5	coated	coated	ADJ
dti-1338	96	6	plastic	plastic	NOUN
dti-1338	96	7	plate	plate	NOUN
dti-1338	96	8	(	(	PUNCT
dti-1338	96	9	fig	fig	NOUN
dti-1338	96	10	.	.	PUNCT
dti-1338	96	11	3a	3a	NUM
dti-1338	96	12	)	)	PUNCT
dti-1338	96	13	,	,	PUNCT
dti-1338	96	14	the	the	DET
dti-1338	96	15	cell	cell	NOUN
dti-1338	96	16	counts	count	VERB
dti-1338	96	17	at	at	ADP
dti-1338	96	18	all	all	DET
dti-1338	96	19	doses	dose	NOUN
dti-1338	96	20	of	of	ADP
dti-1338	96	21	vpa	vpa	PROPN
dti-1338	96	22	,	,	PUNCT
dti-1338	96	23	from	from	ADP
dti-1338	96	24	1	1	NUM
dti-1338	96	25	to	to	ADP
dti-1338	96	26	1000	1000	NUM
dti-1338	96	27	µg	µg	NOUN
dti-1338	96	28	/	/	SYM
dti-1338	96	29	ml	ml	NOUN
dti-1338	96	30	,	,	PUNCT
dti-1338	96	31	were	be	AUX
dti-1338	96	32	significantly	significantly	ADV
dti-1338	96	33	higher	high	ADJ
dti-1338	96	34	following	follow	VERB
dti-1338	96	35	the	the	DET
dti-1338	96	36	96	96	NUM
dti-1338	96	37	-	-	PUNCT
dti-1338	96	38	hour	hour	NOUN
dti-1338	96	39	culture	culture	NOUN
dti-1338	96	40	than	than	ADP
dti-1338	96	41	those	those	PRON
dti-1338	96	42	following	follow	VERB
dti-1338	96	43	the	the	DET
dti-1338	96	44	48	48	NUM
dti-1338	96	45	-	-	PUNCT
dti-1338	96	46	hour	hour	NOUN
dti-1338	96	47	culture	culture	NOUN
dti-1338	96	48	(	(	PUNCT
dti-1338	96	49	n	n	NOUN
dti-1338	96	50	=	=	SYM
dti-1338	96	51	8	8	NUM
dti-1338	96	52	,	,	PUNCT
dti-1338	96	53	p	p	NOUN
dti-1338	96	54	,	,	PUNCT
dti-1338	96	55	0.01	0.01	NUM
dti-1338	96	56	)	)	PUNCT
dti-1338	96	57	.	.	PUNCT
dti-1338	97	1	following	follow	VERB
dti-1338	97	2	both	both	CCONJ
dti-1338	97	3	the	the	DET
dti-1338	97	4	48and	48and	ADJ
dti-1338	97	5	96	96	NUM
dti-1338	97	6	-	-	PUNCT
dti-1338	97	7	hour	hour	NOUN
dti-1338	97	8	culture	culture	NOUN
dti-1338	97	9	periods	period	NOUN
dti-1338	97	10	,	,	PUNCT
dti-1338	97	11	there	there	PRON
dti-1338	97	12	were	be	VERB
dti-1338	97	13	no	no	DET
dti-1338	97	14	significant	significant	ADJ
dti-1338	97	15	cell	cell	NOUN
dti-1338	97	16	number	number	NOUN
dti-1338	97	17	differences	difference	NOUN
dti-1338	97	18	among	among	ADP
dti-1338	97	19	the	the	DET
dti-1338	97	20	vpa	vpa	PROPN
dti-1338	97	21	doses	dose	NOUN
dti-1338	97	22	,	,	PUNCT
dti-1338	97	23	except	except	SCONJ
dti-1338	97	24	for	for	ADP
dti-1338	97	25	at	at	ADP
dti-1338	97	26	the	the	DET
dti-1338	97	27	1000	1000	NUM
dti-1338	97	28	µg	µg	ADJ
dti-1338	97	29	/	/	SYM
dti-1338	97	30	ml	ml	NOUN
dti-1338	97	31	concentration	concentration	NOUN
dti-1338	97	32	on	on	ADP
dti-1338	97	33	the	the	DET
dti-1338	97	34	non	non	ADJ
dti-1338	97	35	-	-	ADJ
dti-1338	97	36	coated	coated	ADJ
dti-1338	97	37	plastic	plastic	NOUN
dti-1338	97	38	plate	plate	NOUN
dti-1338	97	39	(	(	PUNCT
dti-1338	97	40	fig	fig	NOUN
dti-1338	97	41	.	.	PUNCT
dti-1338	97	42	3a	3a	NUM
dti-1338	97	43	)	)	PUNCT
dti-1338	97	44	.	.	PUNCT
dti-1338	98	1	these	these	DET
dti-1338	98	2	results	result	NOUN
dti-1338	98	3	indicated	indicate	VERB
dti-1338	98	4	that	that	SCONJ
dti-1338	98	5	only	only	ADV
dti-1338	98	6	vpa	vpa	PROPN
dti-1338	98	7	at	at	ADP
dti-1338	98	8	a	a	DET
dti-1338	98	9	concentration	concentration	NOUN
dti-1338	98	10	of	of	ADP
dti-1338	98	11	1000	1000	NUM
dti-1338	98	12	µg	µg	NOUN
dti-1338	98	13	/	/	SYM
dti-1338	98	14	ml	ml	NOUN
dti-1338	98	15	reduced	reduce	VERB
dti-1338	98	16	the	the	DET
dti-1338	98	17	mesenchymal	mesenchymal	ADJ
dti-1338	98	18	cell	cell	NOUN
dti-1338	98	19	proliferation	proliferation	NOUN
dti-1338	98	20	level	level	NOUN
dti-1338	98	21	on	on	ADP
dti-1338	98	22	the	the	DET
dti-1338	98	23	non	non	ADJ
dti-1338	98	24	-	-	ADJ
dti-1338	98	25	coated	coated	ADJ
dti-1338	98	26	plastic	plastic	NOUN
dti-1338	98	27	plate	plate	NOUN
dti-1338	98	28	;	;	PUNCT
dti-1338	98	29	however	however	ADV
dti-1338	98	30	in	in	ADP
dti-1338	98	31	the	the	DET
dti-1338	98	32	fibronectinand	fibronectinand	NOUN
dti-1338	98	33	type	type	NOUN
dti-1338	98	34	i	i	PRON
dti-1338	98	35	collagen	collagen	NOUN
dti-1338	98	36	-	-	PUNCT
dti-1338	98	37	coated	coated	ADJ
dti-1338	98	38	plate	plate	NOUN
dti-1338	98	39	culture	culture	NOUN
dti-1338	98	40	,	,	PUNCT
dti-1338	98	41	the	the	DET
dti-1338	98	42	concentration	concentration	NOUN
dti-1338	98	43	of	of	ADP
dti-1338	98	44	vpa	vpa	PROPN
dti-1338	98	45	at	at	ADP
dti-1338	98	46	all	all	DET
dti-1338	98	47	concentrations	concentration	NOUN
dti-1338	98	48	,	,	PUNCT
dti-1338	98	49	from	from	ADP
dti-1338	98	50	1	1	NUM
dti-1338	98	51	to	to	ADP
dti-1338	98	52	1000	1000	NUM
dti-1338	98	53	µg	µg	NOUN
dti-1338	98	54	/	/	SYM
dti-1338	98	55	ml	ml	NOUN
dti-1338	98	56	,	,	PUNCT
dti-1338	98	57	lowered	lower	VERB
dti-1338	98	58	the	the	DET
dti-1338	98	59	mesenchymal	mesenchymal	NOUN
dti-1338	98	60	cell	cell	NOUN
dti-1338	98	61	proliferation	proliferation	NOUN
dti-1338	98	62	level	level	NOUN
dti-1338	98	63	when	when	SCONJ
dti-1338	98	64	compared	compare	VERB
dti-1338	98	65	to	to	ADP
dti-1338	98	66	the	the	DET
dti-1338	98	67	0	0	NUM
dti-1338	98	68	µg	µg	NOUN
dti-1338	98	69	/	/	SYM
dti-1338	98	70	ml	ml	NOUN
dti-1338	98	71	concentration	concentration	NOUN
dti-1338	98	72	on	on	ADP
dti-1338	98	73	fibronectinand	fibronectinand	NOUN
dti-1338	98	74	type	type	NOUN
dti-1338	98	75	i	i	PRON
dti-1338	98	76	collagen	collagen	NOUN
dti-1338	98	77	-coated	-coate	VERB
dti-1338	98	78	plates	plate	NOUN
dti-1338	98	79	at	at	ADP
dti-1338	98	80	each	each	DET
dti-1338	98	81	time	time	NOUN
dti-1338	98	82	period	period	NOUN
dti-1338	98	83	(	(	PUNCT
dti-1338	98	84	fig	fig	NOUN
dti-1338	98	85	.	.	PUNCT
dti-1338	99	1	3b	3b	NOUN
dti-1338	99	2	and	and	CCONJ
dti-1338	99	3	c	c	NOUN
dti-1338	99	4	)	)	PUNCT
dti-1338	99	5	.	.	PUNCT
dti-1338	100	1	in	in	ADP
dti-1338	100	2	the	the	DET
dti-1338	100	3	absence	absence	NOUN
dti-1338	100	4	of	of	ADP
dti-1338	100	5	vpa	vpa	PROPN
dti-1338	100	6	,	,	PUNCT
dti-1338	100	7	mesenchymal	mesenchymal	ADJ
dti-1338	100	8	cell	cell	NOUN
dti-1338	100	9	counts	count	NOUN
dti-1338	100	10	on	on	ADP
dti-1338	100	11	the	the	DET
dti-1338	100	12	ecm	ecm	PROPN
dti-1338	100	13	plates	plate	NOUN
dti-1338	100	14	were	be	AUX
dti-1338	100	15	significantly	significantly	ADV
dti-1338	100	16	higher	high	ADJ
dti-1338	100	17	than	than	ADP
dti-1338	100	18	those	those	PRON
dti-1338	100	19	on	on	ADP
dti-1338	100	20	non	non	ADJ
dti-1338	100	21	-	-	ADJ
dti-1338	100	22	coated	coated	ADJ
dti-1338	100	23	plastic	plastic	NOUN
dti-1338	100	24	plate	plate	NOUN
dti-1338	100	25	following	follow	VERB
dti-1338	100	26	48	48	NUM
dti-1338	100	27	-	-	PUNCT
dti-1338	100	28	hour	hour	NOUN
dti-1338	100	29	culture	culture	NOUN
dti-1338	100	30	periods	period	NOUN
dti-1338	100	31	(	(	PUNCT
dti-1338	100	32	fig	fig	NOUN
dti-1338	100	33	.	.	PUNCT
dti-1338	101	1	3a	3a	NUM
dti-1338	101	2	,	,	PUNCT
dti-1338	101	3	b	b	NOUN
dti-1338	101	4	and	and	CCONJ
dti-1338	101	5	c	c	NOUN
dti-1338	101	6	)	)	PUNCT
dti-1338	101	7	.	.	PUNCT
dti-1338	102	1	when	when	SCONJ
dti-1338	102	2	we	we	PRON
dti-1338	102	3	took	take	VERB
dti-1338	102	4	trypan	trypan	NOUN
dti-1338	102	5	blue	blue	ADJ
dti-1338	102	6	positive	positive	ADJ
dti-1338	102	7	cell	cell	NOUN
dti-1338	102	8	counts	count	NOUN
dti-1338	102	9	in	in	ADP
dti-1338	102	10	a	a	DET
dti-1338	102	11	cell	cell	NOUN
dti-1338	102	12	suspension	suspension	NOUN
dti-1338	102	13	following	follow	VERB
dti-1338	102	14	the	the	DET
dti-1338	102	15	48	48	NUM
dti-1338	102	16	-	-	PUNCT
dti-1338	102	17	hour	hour	NOUN
dti-1338	102	18	and	and	CCONJ
dti-1338	102	19	96	96	NUM
dti-1338	102	20	-	-	PUNCT
dti-1338	102	21	hour	hour	NOUN
dti-1338	102	22	culture	culture	NOUN
dti-1338	102	23	,	,	PUNCT
dti-1338	102	24	ratios	ratio	NOUN
dti-1338	102	25	of	of	ADP
dti-1338	102	26	viable	viable	ADJ
dti-1338	102	27	cells	cell	NOUN
dti-1338	102	28	in	in	ADP
dti-1338	102	29	non	non	ADJ
dti-1338	102	30	-	-	ADJ
dti-1338	102	31	coated	coated	ADJ
dti-1338	102	32	plastic	plastic	NOUN
dti-1338	102	33	plate	plate	NOUN
dti-1338	102	34	were	be	AUX
dti-1338	102	35	no	no	DET
dti-1338	102	36	significant	significant	ADJ
dti-1338	102	37	differences	difference	NOUN
dti-1338	102	38	found	find	VERB
dti-1338	102	39	among	among	ADP
dti-1338	102	40	the	the	DET
dti-1338	102	41	vpa	vpa	PROPN
dti-1338	102	42	concentrations	concentration	NOUN
dti-1338	102	43	(	(	PUNCT
dti-1338	102	44	fig	fig	NOUN
dti-1338	102	45	.	.	PUNCT
dti-1338	103	1	3d	3d	NUM
dti-1338	103	2	,	,	PUNCT
dti-1338	103	3	normal	normal	ADJ
dti-1338	103	4	)	)	PUNCT
dti-1338	103	5	.	.	PUNCT
dti-1338	104	1	on	on	ADP
dti-1338	104	2	the	the	DET
dti-1338	104	3	ecm	ecm	PROPN
dti-1338	104	4	plates	plate	NOUN
dti-1338	104	5	,	,	PUNCT
dti-1338	104	6	ratios	ratio	NOUN
dti-1338	104	7	of	of	ADP
dti-1338	104	8	viable	viable	ADJ
dti-1338	104	9	cells	cell	NOUN
dti-1338	104	10	at	at	ADP
dti-1338	104	11	the	the	DET
dti-1338	104	12	10	10	NUM
dti-1338	104	13	µg	µg	NOUN
dti-1338	104	14	/	/	SYM
dti-1338	104	15	ml	ml	NOUN
dti-1338	104	16	were	be	AUX
dti-1338	104	17	no	no	DET
dti-1338	104	18	significant	significant	ADJ
dti-1338	104	19	differences	difference	NOUN
dti-1338	104	20	comparing	compare	VERB
dti-1338	104	21	with	with	ADP
dti-1338	104	22	0	0	NUM
dti-1338	104	23	mg	mg	NUM
dti-1338	104	24	/	/	SYM
dti-1338	104	25	ml	ml	NOUN
dti-1338	104	26	following	follow	VERB
dti-1338	104	27	the	the	DET
dti-1338	104	28	48	48	NUM
dti-1338	104	29	-	-	PUNCT
dti-1338	104	30	hour	hour	NOUN
dti-1338	104	31	and	and	CCONJ
dti-1338	104	32	96	96	NUM
dti-1338	104	33	-	-	PUNCT
dti-1338	104	34	hour	hour	NOUN
dti-1338	104	35	culture	culture	NOUN
dti-1338	104	36	(	(	PUNCT
dti-1338	104	37	fig	fig	NOUN
dti-1338	104	38	.	.	PUNCT
dti-1338	105	1	3d	3d	NUM
dti-1338	105	2	)	)	PUNCT
dti-1338	105	3	.	.	PUNCT
dti-1338	106	1	these	these	DET
dti-1338	106	2	results	result	NOUN
dti-1338	106	3	indicated	indicate	VERB
dti-1338	106	4	that	that	SCONJ
dti-1338	106	5	vpa	vpa	PROPN
dti-1338	106	6	could	could	AUX
dti-1338	106	7	reduce	reduce	VERB
dti-1338	106	8	mesenchymal	mesenchymal	NOUN
dti-1338	106	9	cell	cell	NOUN
dti-1338	106	10	proliferation	proliferation	NOUN
dti-1338	106	11	level	level	NOUN
dti-1338	106	12	at	at	ADP
dti-1338	106	13	a	a	DET
dti-1338	106	14	relatively	relatively	ADV
dti-1338	106	15	high	high	ADJ
dti-1338	106	16	concentration	concentration	NOUN
dti-1338	106	17	in	in	ADP
dti-1338	106	18	the	the	DET
dti-1338	106	19	absence	absence	NOUN
dti-1338	106	20	of	of	ADP
dti-1338	106	21	ecms	ecms	NOUN
dti-1338	106	22	;	;	PUNCT
dti-1338	106	23	however	however	ADV
dti-1338	106	24	,	,	PUNCT
dti-1338	106	25	this	this	DET
dti-1338	106	26	reducibility	reducibility	NOUN
dti-1338	106	27	effect	effect	NOUN
dti-1338	106	28	is	be	AUX
dti-1338	106	29	enhanced	enhance	VERB
dti-1338	106	30	at	at	ADP
dti-1338	106	31	relatively	relatively	ADV
dti-1338	106	32	low	low	ADJ
dti-1338	106	33	concentrations	concentration	NOUN
dti-1338	106	34	in	in	ADP
dti-1338	106	35	the	the	DET
dti-1338	106	36	presence	presence	NOUN
dti-1338	106	37	of	of	ADP
dti-1338	106	38	ecms	ecms	NOUN
dti-1338	106	39	.	.	PUNCT
dti-1338	107	1	cell	cell	NOUN
dti-1338	107	2	differentiation	differentiation	NOUN
dti-1338	107	3	since	since	SCONJ
dti-1338	107	4	a	a	DET
dti-1338	107	5	previous	previous	ADJ
dti-1338	107	6	report	report	NOUN
dti-1338	107	7	indicated	indicate	VERB
dti-1338	107	8	that	that	SCONJ
dti-1338	107	9	vpa	vpa	PROPN
dti-1338	107	10	promoted	promote	VERB
dti-1338	107	11	osteoblastic	osteoblastic	ADJ
dti-1338	107	12	cell	cell	NOUN
dti-1338	107	13	differentiation	differentiation	NOUN
dti-1338	107	14	from	from	ADP
dti-1338	107	15	a	a	DET
dti-1338	107	16	pre	pre	ADJ
dti-1338	107	17	-	-	ADJ
dti-1338	107	18	osteoblastic	osteoblastic	ADJ
dti-1338	107	19	0	0	NUM
dti-1338	107	20	1	1	NUM
dti-1338	107	21	10	10	NUM
dti-1338	107	22	100	100	NUM
dti-1338	107	23	1000	1000	NUM
dti-1338	107	24	normal	normal	ADJ
dti-1338	107	25	48	48	NUM
dti-1338	107	26	hr	hr	NOUN
dti-1338	107	27	96	96	NUM
dti-1338	107	28	hr	hr	NOUN
dti-1338	107	29	fibronectin	fibronectin	NOUN
dti-1338	107	30	vpa	vpa	PROPN
dti-1338	107	31	concentration	concentration	NOUN
dti-1338	107	32	type	type	NOUN
dti-1338	107	33	i	i	PRON
dti-1338	107	34	collagen	collagen	VERB
dti-1338	107	35	0.3	0.3	NUM
dti-1338	107	36	0	0	NUM
dti-1338	107	37	0.6	0.6	NUM
dti-1338	107	38	0.9	0.9	NUM
dti-1338	107	39	1.2	1.2	NUM
dti-1338	107	40	1.5	1.5	NUM
dti-1338	107	41	1.8	1.8	NUM
dti-1338	107	42	0.3	0.3	NUM
dti-1338	107	43	0	0	NUM
dti-1338	107	44	0.6	0.6	NUM
dti-1338	107	45	0.9	0.9	NUM
dti-1338	107	46	1.2	1.2	NUM
dti-1338	107	47	1.5	1.5	NUM
dti-1338	107	48	1.8	1.8	NUM
dti-1338	107	49	0.3	0.3	NUM
dti-1338	107	50	0	0	NUM
dti-1338	107	51	0.6	0.6	NUM
dti-1338	107	52	0.9	0.9	NUM
dti-1338	107	53	1.2	1.2	NUM
dti-1338	107	54	1.5	1.5	NUM
dti-1338	107	55	1.8	1.8	NUM
dti-1338	107	56	a	a	DET
dti-1338	107	57	b	b	NOUN
dti-1338	107	58	c	c	NOUN
dti-1338	107	59	*	*	PUNCT
dti-1338	107	60	*	*	PUNCT
dti-1338	107	61	normal	normal	ADJ
dti-1338	107	62	fbn	fbn	NOUN
dti-1338	107	63	48	48	NUM
dti-1338	107	64	hr	hr	NOUN
dti-1338	107	65	96	96	NUM
dti-1338	107	66	hr	hr	NOUN
dti-1338	107	67	col1	col1	PROPN
dti-1338	107	68	normal	normal	ADJ
dti-1338	107	69	fbn	fbn	VERB
dti-1338	107	70	col1	col1	NOUN
dti-1338	108	1	*	*	PUNCT
dti-1338	109	1	*	*	PUNCT
dti-1338	109	2	d	d	PUNCT
dti-1338	109	3	*	*	PUNCT
dti-1338	109	4	*	*	PUNCT
dti-1338	109	5	*	*	PUNCT
dti-1338	109	6	*	*	PUNCT
dti-1338	110	1	*	*	PUNCT
dti-1338	110	2	*	*	PUNCT
dti-1338	111	1	*	*	PUNCT
dti-1338	112	1	*	*	PUNCT
dti-1338	112	2	*	*	PUNCT
dti-1338	113	1	*	*	PUNCT
dti-1338	114	1	*	*	PUNCT
dti-1338	114	2	*	*	PUNCT
dti-1338	114	3	*	*	PUNCT
dti-1338	114	4	*	*	PUNCT
dti-1338	115	1	*	*	PUNCT
dti-1338	115	2	*	*	PUNCT
dti-1338	115	3	*	*	PUNCT
dti-1338	115	4	*	*	PUNCT
dti-1338	116	1	*	*	PUNCT
dti-1338	116	2	*	*	PUNCT
dti-1338	116	3	*	*	PUNCT
dti-1338	116	4	*	*	PUNCT
dti-1338	117	1	*	*	PUNCT
dti-1338	117	2	*	*	PUNCT
dti-1338	117	3	*	*	PUNCT
dti-1338	117	4	*	*	PUNCT
dti-1338	118	1	*	*	PUNCT
dti-1338	118	2	*	*	PUNCT
dti-1338	118	3	*	*	PUNCT
dti-1338	118	4	*	*	PUNCT
dti-1338	119	1	*	*	PUNCT
dti-1338	119	2	*	*	PUNCT
dti-1338	119	3	*	*	PUNCT
dti-1338	119	4	*	*	PUNCT
dti-1338	120	1	o	o	PUNCT
dti-1338	120	2	d	d	X
dti-1338	120	3	v	v	X
dti-1338	120	4	al	al	PROPN
dti-1338	120	5	u	u	PROPN
dti-1338	120	6	e	e	NOUN
dti-1338	120	7	at	at	ADP
dti-1338	120	8	4	4	NUM
dti-1338	120	9	50	50	NUM
dti-1338	120	10	n	n	NOUN
dti-1338	120	11	m	m	NOUN
dti-1338	120	12	r	r	NOUN
dti-1338	120	13	at	at	ADP
dti-1338	120	14	io	io	X
dti-1338	120	15	o	o	PROPN
dti-1338	120	16	f	f	PROPN
dti-1338	120	17	vi	vi	X
dti-1338	120	18	ab	ab	X
dti-1338	120	19	le	le	PROPN
dti-1338	120	20	c	c	PROPN
dti-1338	120	21	el	el	PROPN
dti-1338	120	22	ls	ls	PROPN
dti-1338	120	23	to	to	ADP
dti-1338	120	24	t	t	PROPN
dti-1338	120	25	o	o	X
dti-1338	120	26	ta	ta	ADP
dti-1338	120	27	l	l	PROPN
dti-1338	120	28	c	c	PROPN
dti-1338	120	29	el	el	PROPN
dti-1338	120	30	ls	ls	PROPN
dti-1338	120	31	(	(	PUNCT
dti-1338	120	32	%	%	NOUN
dti-1338	120	33	)	)	PUNCT
dti-1338	120	34	(	(	PUNCT
dti-1338	120	35	µg	µg	NOUN
dti-1338	120	36	/	/	SYM
dti-1338	120	37	ml	ml	NOUN
dti-1338	120	38	)	)	PUNCT
dti-1338	120	39	(	(	PUNCT
dti-1338	120	40	vpa	vpa	PROPN
dti-1338	120	41	µg	µg	PROPN
dti-1338	120	42	/	/	SYM
dti-1338	120	43	ml	ml	NOUN
dti-1338	120	44	)	)	PUNCT
dti-1338	120	45	0	0	NUM
dti-1338	120	46	1	1	NUM
dti-1338	120	47	10	10	NUM
dti-1338	120	48	100	100	NUM
dti-1338	120	49	1000	1000	NUM
dti-1338	120	50	(	(	PUNCT
dti-1338	120	51	µg	µg	NOUN
dti-1338	120	52	/	/	SYM
dti-1338	120	53	ml	ml	NOUN
dti-1338	120	54	)	)	PUNCT
dti-1338	120	55	0	0	NUM
dti-1338	120	56	1	1	NUM
dti-1338	120	57	10	10	NUM
dti-1338	120	58	100	100	NUM
dti-1338	120	59	1000	1000	NUM
dti-1338	120	60	(	(	PUNCT
dti-1338	120	61	µg	µg	NOUN
dti-1338	120	62	/	/	SYM
dti-1338	120	63	ml	ml	NOUN
dti-1338	120	64	)	)	PUNCT
dti-1338	120	65	*	*	PUNCT
dti-1338	121	1	*	*	PUNCT
dti-1338	121	2	*	*	PUNCT
dti-1338	121	3	0	0	NUM
dti-1338	121	4	10	10	NUM
dti-1338	121	5	100	100	NUM
dti-1338	121	6	1000	1000	NUM
dti-1338	121	7	100	100	NUM
dti-1338	121	8	80	80	NUM
dti-1338	121	9	60	60	NUM
dti-1338	121	10	40	40	NUM
dti-1338	121	11	20	20	NUM
dti-1338	121	12	0	0	NUM
dti-1338	121	13	figure	figure	NOUN
dti-1338	121	14	3	3	NUM
dti-1338	121	15	.	.	PUNCT
dti-1338	122	1	vpa	vpa	PROPN
dti-1338	122	2	reduced	reduce	VERB
dti-1338	122	3	mesenchymal	mesenchymal	NOUN
dti-1338	122	4	cell	cell	NOUN
dti-1338	122	5	proliferation	proliferation	NOUN
dti-1338	122	6	level	level	NOUN
dti-1338	122	7	in	in	ADP
dti-1338	122	8	the	the	DET
dti-1338	122	9	presence	presence	NOUN
dti-1338	122	10	of	of	ADP
dti-1338	122	11	ecms	ecms	NOUN
dti-1338	122	12	.	.	PUNCT
dti-1338	123	1	mesenchymal	mesenchymal	ADJ
dti-1338	123	2	cells	cell	NOUN
dti-1338	123	3	were	be	AUX
dti-1338	123	4	cultured	cultured	ADJ
dti-1338	123	5	in	in	ADP
dti-1338	123	6	the	the	DET
dti-1338	123	7	absence	absence	NOUN
dti-1338	123	8	(	(	PUNCT
dti-1338	123	9	normal	normal	ADJ
dti-1338	123	10	,	,	PUNCT
dti-1338	123	11	a	a	NOUN
dti-1338	123	12	)	)	PUNCT
dti-1338	123	13	or	or	CCONJ
dti-1338	123	14	presence	presence	NOUN
dti-1338	123	15	(	(	PUNCT
dti-1338	123	16	fibronectin	fibronectin	NOUN
dti-1338	123	17	(	(	PUNCT
dti-1338	123	18	b	b	NOUN
dti-1338	123	19	)	)	PUNCT
dti-1338	123	20	and	and	CCONJ
dti-1338	123	21	type	type	NOUN
dti-1338	124	1	i	i	PRON
dti-1338	124	2	collagen	collagen	NOUN
dti-1338	124	3	(	(	PUNCT
dti-1338	124	4	c	c	NOUN
dti-1338	124	5	)	)	PUNCT
dti-1338	124	6	)	)	PUNCT
dti-1338	124	7	of	of	ADP
dti-1338	124	8	extracellular	extracellular	ADJ
dti-1338	124	9	matrices	matrix	NOUN
dti-1338	124	10	for	for	ADP
dti-1338	124	11	48	48	NUM
dti-1338	124	12	and	and	CCONJ
dti-1338	124	13	96	96	NUM
dti-1338	124	14	hours	hour	NOUN
dti-1338	124	15	.	.	PUNCT
dti-1338	125	1	relative	relative	ADJ
dti-1338	125	2	cell	cell	NOUN
dti-1338	125	3	number	number	NOUN
dti-1338	125	4	was	be	AUX
dti-1338	125	5	indicated	indicate	VERB
dti-1338	125	6	by	by	ADP
dti-1338	125	7	light	light	ADJ
dti-1338	125	8	absorbance	absorbance	NOUN
dti-1338	125	9	at	at	ADP
dti-1338	125	10	a	a	DET
dti-1338	125	11	wavelength	wavelength	NOUN
dti-1338	125	12	of	of	ADP
dti-1338	125	13	450	450	NUM
dti-1338	125	14	nm	nm	NOUN
dti-1338	125	15	of	of	ADP
dti-1338	125	16	a	a	DET
dti-1338	125	17	formazan	formazan	ADJ
dti-1338	125	18	dye	dye	NOUN
dti-1338	125	19	product	product	NOUN
dti-1338	125	20	in	in	ADP
dti-1338	125	21	the	the	DET
dti-1338	125	22	culture	culture	NOUN
dti-1338	125	23	.	.	PUNCT
dti-1338	126	1	vpa	vpa	PROPN
dti-1338	126	2	,	,	PUNCT
dti-1338	126	3	at	at	ADP
dti-1338	126	4	relatively	relatively	ADV
dti-1338	126	5	low	low	ADJ
dti-1338	126	6	concentrations	concentration	NOUN
dti-1338	126	7	,	,	PUNCT
dti-1338	126	8	had	have	VERB
dti-1338	126	9	no	no	DET
dti-1338	126	10	obvious	obvious	ADJ
dti-1338	126	11	inhibitory	inhibitory	ADJ
dti-1338	126	12	effect	effect	NOUN
dti-1338	126	13	on	on	ADP
dti-1338	126	14	mesenchymal	mesenchymal	ADJ
dti-1338	126	15	cell	cell	NOUN
dti-1338	126	16	proliferation	proliferation	NOUN
dti-1338	126	17	when	when	SCONJ
dti-1338	126	18	cultured	cultured	ADJ
dti-1338	126	19	in	in	ADP
dti-1338	126	20	the	the	DET
dti-1338	126	21	absence	absence	NOUN
dti-1338	126	22	of	of	ADP
dti-1338	126	23	ecm	ecm	NOUN
dti-1338	126	24	(	(	PUNCT
dti-1338	126	25	a	a	NOUN
dti-1338	126	26	)	)	PUNCT
dti-1338	126	27	;	;	PUNCT
dti-1338	126	28	however	however	ADV
dti-1338	126	29	,	,	PUNCT
dti-1338	126	30	in	in	ADP
dti-1338	126	31	the	the	DET
dti-1338	126	32	presence	presence	NOUN
dti-1338	126	33	of	of	ADP
dti-1338	126	34	ecm	ecm	PROPN
dti-1338	126	35	,	,	PUNCT
dti-1338	126	36	vpa	vpa	PROPN
dti-1338	126	37	reduced	reduce	VERB
dti-1338	126	38	mesenchymal	mesenchymal	NOUN
dti-1338	126	39	cell	cell	NOUN
dti-1338	126	40	proliferation	proliferation	NOUN
dti-1338	126	41	level	level	NOUN
dti-1338	126	42	in	in	ADP
dti-1338	126	43	a	a	DET
dti-1338	126	44	dosedependent	dosedependent	NOUN
dti-1338	126	45	manner	manner	NOUN
dti-1338	126	46	(	(	PUNCT
dti-1338	126	47	b	b	NOUN
dti-1338	126	48	,	,	PUNCT
dti-1338	126	49	c	c	NOUN
dti-1338	126	50	)	)	PUNCT
dti-1338	126	51	.	.	PUNCT
dti-1338	127	1	d	d	X
dti-1338	127	2	)	)	PUNCT
dti-1338	127	3	the	the	DET
dti-1338	127	4	ratios	ratio	NOUN
dti-1338	127	5	of	of	ADP
dti-1338	127	6	viable	viable	ADJ
dti-1338	127	7	cells	cell	NOUN
dti-1338	127	8	on	on	ADP
dti-1338	127	9	the	the	DET
dti-1338	127	10	ecm	ecm	PROPN
dti-1338	127	11	plates	plate	NOUN
dti-1338	127	12	(	(	PUNCT
dti-1338	127	13	fibronectin	fibronectin	NOUN
dti-1338	127	14	(	(	PUNCT
dti-1338	127	15	fbn	fbn	NOUN
dti-1338	127	16	)	)	PUNCT
dti-1338	127	17	,	,	PUNCT
dti-1338	127	18	type	type	NOUN
dti-1338	127	19	i	i	PRON
dti-1338	127	20	collagen	collagen	NOUN
dti-1338	127	21	(	(	PUNCT
dti-1338	127	22	col1	col1	PROPN
dti-1338	127	23	)	)	PUNCT
dti-1338	127	24	)	)	PUNCT
dti-1338	127	25	were	be	AUX
dti-1338	127	26	not	not	PART
dti-1338	127	27	decreased	decrease	VERB
dti-1338	127	28	significantly	significantly	ADV
dti-1338	127	29	at	at	ADP
dti-1338	127	30	10	10	NUM
dti-1338	127	31	µg	µg	NOUN
dti-1338	127	32	/	/	SYM
dti-1338	127	33	ml	ml	NOUN
dti-1338	127	34	following	follow	VERB
dti-1338	127	35	48	48	NUM
dti-1338	127	36	hrand	hrand	NOUN
dti-1338	127	37	96	96	NUM
dti-1338	127	38	hr	hr	NOUN
dti-1338	127	39	-	-	PUNCT
dti-1338	127	40	culture	culture	NOUN
dti-1338	127	41	period	period	NOUN
dti-1338	127	42	.	.	PUNCT
dti-1338	128	1	n	n	NOUN
dti-1338	129	1	=	=	SYM
dti-1338	129	2	8	8	NUM
dti-1338	129	3	in	in	ADP
dti-1338	129	4	each	each	DET
dti-1338	129	5	experiment	experiment	NOUN
dti-1338	129	6	group	group	NOUN
dti-1338	129	7	.	.	PUNCT
dti-1338	130	1	notes	note	VERB
dti-1338	130	2	:	:	PUNCT
dti-1338	130	3	*	*	PUNCT
dti-1338	130	4	p	p	NOUN
dti-1338	130	5	,	,	PUNCT
dti-1338	130	6	0.05	0.05	NUM
dti-1338	130	7	;	;	PUNCT
dti-1338	130	8	*	*	PUNCT
dti-1338	130	9	*	*	PUNCT
dti-1338	130	10	p	p	X
dti-1338	130	11	,	,	PUNCT
dti-1338	130	12	0.01	0.01	NUM
dti-1338	130	13	compared	compare	VERB
dti-1338	130	14	to	to	ADP
dti-1338	130	15	0	0	NUM
dti-1338	130	16	µg	µg	NOUN
dti-1338	130	17	/	/	SYM
dti-1338	130	18	ml	ml	NOUN
dti-1338	130	19	for	for	ADP
dti-1338	130	20	each	each	DET
dti-1338	130	21	time	time	NOUN
dti-1338	130	22	period	period	NOUN
dti-1338	130	23	.	.	PUNCT
dti-1338	131	1	http://www.la-press.com	http://www.la-press.com	X
dti-1338	131	2	hatakeyama	hatakeyama	PROPN
dti-1338	131	3	et	et	PROPN
dti-1338	131	4	al	al	PROPN
dti-1338	131	5	6	6	NUM
dti-1338	131	6	drug	drug	NOUN
dti-1338	131	7	target	target	NOUN
dti-1338	131	8	insights	insight	NOUN
dti-1338	131	9	2011:5	2011:5	NUM
dti-1338	131	10	cell	cell	NOUN
dti-1338	131	11	line,4	line,4	NOUN
dti-1338	131	12	we	we	PRON
dti-1338	131	13	tested	test	VERB
dti-1338	131	14	whether	whether	SCONJ
dti-1338	131	15	vpa	vpa	PROPN
dti-1338	131	16	promotes	promote	VERB
dti-1338	131	17	the	the	DET
dti-1338	131	18	expression	expression	NOUN
dti-1338	131	19	of	of	ADP
dti-1338	131	20	osteoblastic	osteoblastic	ADJ
dti-1338	131	21	marker	marker	NOUN
dti-1338	131	22	genes	gene	NOUN
dti-1338	131	23	during	during	ADP
dti-1338	131	24	sequential	sequential	ADJ
dti-1338	131	25	cell	cell	NOUN
dti-1338	131	26	differentiation	differentiation	NOUN
dti-1338	131	27	from	from	ADP
dti-1338	131	28	mesenchymal	mesenchymal	ADJ
dti-1338	131	29	cells	cell	NOUN
dti-1338	131	30	to	to	ADP
dti-1338	131	31	osteoblasts	osteoblast	NOUN
dti-1338	131	32	both	both	CCONJ
dti-1338	131	33	in	in	ADP
dti-1338	131	34	the	the	DET
dti-1338	131	35	absence	absence	NOUN
dti-1338	131	36	or	or	CCONJ
dti-1338	131	37	presence	presence	NOUN
dti-1338	131	38	of	of	ADP
dti-1338	131	39	an	an	DET
dti-1338	131	40	extracellular	extracellular	ADJ
dti-1338	131	41	matrix	matrix	NOUN
dti-1338	131	42	,	,	PUNCT
dti-1338	131	43	when	when	SCONJ
dti-1338	131	44	cultured	cultured	ADJ
dti-1338	131	45	on	on	ADP
dti-1338	131	46	non	non	ADJ
dti-1338	131	47	-	-	ADJ
dti-1338	131	48	coated	coated	ADJ
dti-1338	131	49	plastic	plastic	NOUN
dti-1338	131	50	or	or	CCONJ
dti-1338	131	51	type	type	NOUN
dti-1338	131	52	i	i	PRON
dti-1338	131	53	collagen	collagen	NOUN
dti-1338	131	54	-	-	PUNCT
dti-1338	131	55	coated	coat	VERB
dti-1338	131	56	plates	plate	NOUN
dti-1338	131	57	.	.	PUNCT
dti-1338	132	1	in	in	ADP
dti-1338	132	2	the	the	DET
dti-1338	132	3	absence	absence	NOUN
dti-1338	132	4	of	of	ADP
dti-1338	132	5	vpa	vpa	PROPN
dti-1338	132	6	,	,	PUNCT
dti-1338	132	7	the	the	DET
dti-1338	132	8	gene	gene	NOUN
dti-1338	132	9	expressions	expression	NOUN
dti-1338	132	10	of	of	ADP
dti-1338	132	11	collagenous	collagenous	ADJ
dti-1338	132	12	and	and	CCONJ
dti-1338	132	13	of	of	ADP
dti-1338	132	14	noncollagenous	noncollagenous	ADJ
dti-1338	132	15	bone	bone	NOUN
dti-1338	132	16	matrices	matrix	NOUN
dti-1338	132	17	(	(	PUNCT
dti-1338	132	18	ie	ie	X
dti-1338	132	19	,	,	PUNCT
dti-1338	132	20	collagen	collagen	NOUN
dti-1338	132	21	1α2	1α2	NUM
dti-1338	132	22	,	,	PUNCT
dti-1338	132	23	osteopontin	osteopontin	NOUN
dti-1338	132	24	and	and	CCONJ
dti-1338	132	25	osteocalcin	osteocalcin	PROPN
dti-1338	132	26	,	,	PUNCT
dti-1338	132	27	which	which	PRON
dti-1338	132	28	are	be	AUX
dti-1338	132	29	osteoblastic	osteoblastic	ADJ
dti-1338	132	30	marker	marker	NOUN
dti-1338	132	31	genes	gene	NOUN
dti-1338	132	32	)	)	PUNCT
dti-1338	132	33	were	be	AUX
dti-1338	132	34	detected	detect	VERB
dti-1338	132	35	in	in	ADP
dti-1338	132	36	the	the	DET
dti-1338	132	37	mesenchymal	mesenchymal	NOUN
dti-1338	132	38	cells	cell	NOUN
dti-1338	132	39	cultured	cultured	ADJ
dti-1338	132	40	on	on	ADP
dti-1338	132	41	a	a	DET
dti-1338	132	42	non	non	ADJ
dti-1338	132	43	-	-	ADJ
dti-1338	132	44	coated	coated	ADJ
dti-1338	132	45	plastic	plastic	NOUN
dti-1338	132	46	plate	plate	NOUN
dti-1338	132	47	with	with	ADP
dti-1338	132	48	an	an	DET
dti-1338	132	49	inductive	inductive	ADJ
dti-1338	132	50	medium	medium	NOUN
dti-1338	132	51	of	of	ADP
dti-1338	132	52	osteoblastic	osteoblastic	ADJ
dti-1338	132	53	cell	cell	NOUN
dti-1338	132	54	differentiation	differentiation	NOUN
dti-1338	132	55	after	after	ADP
dti-1338	132	56	a	a	DET
dti-1338	132	57	one	one	NUM
dti-1338	132	58	-	-	PUNCT
dti-1338	132	59	week	week	NOUN
dti-1338	132	60	culture	culture	NOUN
dti-1338	132	61	(	(	PUNCT
dti-1338	132	62	fig	fig	NOUN
dti-1338	132	63	.	.	PUNCT
dti-1338	133	1	4a	4a	NUM
dti-1338	133	2	,	,	PUNCT
dti-1338	133	3	b	b	NOUN
dti-1338	133	4	,	,	PUNCT
dti-1338	133	5	c	c	NOUN
dti-1338	133	6	,	,	PUNCT
dti-1338	133	7	d	d	NOUN
dti-1338	133	8	;	;	PUNCT
dti-1338	133	9	normal	normal	ADJ
dti-1338	133	10	)	)	PUNCT
dti-1338	133	11	.	.	PUNCT
dti-1338	134	1	the	the	DET
dti-1338	134	2	expression	expression	NOUN
dti-1338	134	3	levels	level	NOUN
dti-1338	134	4	of	of	ADP
dti-1338	134	5	these	these	DET
dti-1338	134	6	marker	marker	NOUN
dti-1338	134	7	genes	gene	NOUN
dti-1338	134	8	were	be	AUX
dti-1338	134	9	significantly	significantly	ADV
dti-1338	134	10	promoted	promote	VERB
dti-1338	134	11	in	in	ADP
dti-1338	134	12	the	the	DET
dti-1338	134	13	presence	presence	NOUN
dti-1338	134	14	of	of	ADP
dti-1338	134	15	1	1	NUM
dti-1338	134	16	µg	µg	NOUN
dti-1338	134	17	/	/	SYM
dti-1338	134	18	ml	ml	ADP
dti-1338	134	19	vpa	vpa	PROPN
dti-1338	134	20	,	,	PUNCT
dti-1338	134	21	except	except	SCONJ
dti-1338	134	22	in	in	ADP
dti-1338	134	23	the	the	DET
dti-1338	134	24	case	case	NOUN
dti-1338	134	25	of	of	ADP
dti-1338	134	26	bsp	bsp	NOUN
dti-1338	134	27	.	.	PUNCT
dti-1338	135	1	similar	similar	ADJ
dti-1338	135	2	to	to	ADP
dti-1338	135	3	the	the	DET
dti-1338	135	4	results	result	NOUN
dti-1338	135	5	in	in	ADP
dti-1338	135	6	the	the	DET
dti-1338	135	7	cell	cell	NOUN
dti-1338	135	8	culture	culture	NOUN
dti-1338	135	9	on	on	ADP
dti-1338	135	10	the	the	DET
dti-1338	135	11	non	non	ADJ
dti-1338	135	12	-	-	ADJ
dti-1338	135	13	coated	coated	ADJ
dti-1338	135	14	plastic	plastic	NOUN
dti-1338	135	15	plate	plate	NOUN
dti-1338	135	16	,	,	PUNCT
dti-1338	135	17	vpa	vpa	PROPN
dti-1338	135	18	significantly	significantly	ADV
dti-1338	135	19	promoted	promote	VERB
dti-1338	135	20	the	the	DET
dti-1338	135	21	expression	expression	NOUN
dti-1338	135	22	level	level	NOUN
dti-1338	135	23	of	of	ADP
dti-1338	135	24	all	all	DET
dti-1338	135	25	genes	gene	NOUN
dti-1338	135	26	,	,	PUNCT
dti-1338	135	27	except	except	SCONJ
dti-1338	135	28	for	for	ADP
dti-1338	135	29	that	that	PRON
dti-1338	135	30	of	of	ADP
dti-1338	135	31	bsp	bsp	NOUN
dti-1338	135	32	,	,	PUNCT
dti-1338	135	33	when	when	SCONJ
dti-1338	135	34	compared	compare	VERB
dti-1338	135	35	with	with	ADP
dti-1338	135	36	the	the	DET
dti-1338	135	37	absence	absence	NOUN
dti-1338	135	38	of	of	ADP
dti-1338	135	39	vpa	vpa	PROPN
dti-1338	135	40	in	in	ADP
dti-1338	135	41	the	the	DET
dti-1338	135	42	cell	cell	NOUN
dti-1338	135	43	culture	culture	NOUN
dti-1338	135	44	on	on	ADP
dti-1338	135	45	the	the	DET
dti-1338	135	46	collagen	collagen	NOUN
dti-1338	135	47	-	-	PUNCT
dti-1338	135	48	coated	coated	ADJ
dti-1338	135	49	plate	plate	NOUN
dti-1338	135	50	(	(	PUNCT
dti-1338	135	51	fig	fig	NOUN
dti-1338	135	52	.	.	PUNCT
dti-1338	136	1	4a	4a	NUM
dti-1338	136	2	,	,	PUNCT
dti-1338	136	3	b	b	NOUN
dti-1338	136	4	,	,	PUNCT
dti-1338	136	5	c	c	NOUN
dti-1338	136	6	,	,	PUNCT
dti-1338	136	7	d	d	NOUN
dti-1338	136	8	;	;	PUNCT
dti-1338	136	9	collagen	collagen	NOUN
dti-1338	136	10	)	)	PUNCT
dti-1338	136	11	.	.	PUNCT
dti-1338	137	1	furthermore	furthermore	ADV
dti-1338	137	2	the	the	DET
dti-1338	137	3	increase	increase	NOUN
dti-1338	137	4	in	in	ADP
dti-1338	137	5	these	these	DET
dti-1338	137	6	gene	gene	NOUN
dti-1338	137	7	expression	expression	NOUN
dti-1338	137	8	levels	level	NOUN
dti-1338	137	9	was	be	AUX
dti-1338	137	10	higher	high	ADJ
dti-1338	137	11	than	than	ADP
dti-1338	137	12	that	that	PRON
dti-1338	137	13	of	of	ADP
dti-1338	137	14	the	the	DET
dti-1338	137	15	non	non	ADJ
dti-1338	137	16	-	-	ADJ
dti-1338	137	17	coated	coated	ADJ
dti-1338	137	18	plastic	plastic	NOUN
dti-1338	137	19	plate	plate	NOUN
dti-1338	137	20	both	both	CCONJ
dti-1338	137	21	in	in	ADP
dti-1338	137	22	the	the	DET
dti-1338	137	23	absence	absence	NOUN
dti-1338	137	24	or	or	CCONJ
dti-1338	137	25	presence	presence	NOUN
dti-1338	137	26	of	of	ADP
dti-1338	137	27	vpa	vpa	PROPN
dti-1338	137	28	.	.	PUNCT
dti-1338	138	1	these	these	DET
dti-1338	138	2	results	result	NOUN
dti-1338	138	3	indicate	indicate	VERB
dti-1338	138	4	that	that	SCONJ
dti-1338	138	5	vpa	vpa	PROPN
dti-1338	138	6	promoted	promote	VERB
dti-1338	138	7	osteoblastic	osteoblastic	ADJ
dti-1338	138	8	cell	cell	NOUN
dti-1338	138	9	differentiation	differentiation	NOUN
dti-1338	138	10	from	from	ADP
dti-1338	138	11	mesenchymal	mesenchymal	ADJ
dti-1338	138	12	cells	cell	NOUN
dti-1338	138	13	cultured	cultured	ADJ
dti-1338	138	14	on	on	ADP
dti-1338	138	15	the	the	DET
dti-1338	138	16	non	non	ADJ
dti-1338	138	17	-	-	ADJ
dti-1338	138	18	coated	coated	ADJ
dti-1338	138	19	plastic	plastic	NOUN
dti-1338	138	20	plate	plate	NOUN
dti-1338	138	21	and	and	CCONJ
dti-1338	138	22	the	the	DET
dti-1338	138	23	co	co	NOUN
dti-1338	138	24	-	-	NOUN
dti-1338	138	25	presence	presence	NOUN
dti-1338	138	26	of	of	ADP
dti-1338	138	27	an	an	DET
dti-1338	138	28	extracellular	extracellular	ADJ
dti-1338	138	29	matrix	matrix	NOUN
dti-1338	138	30	promoted	promote	VERB
dti-1338	138	31	osteoblastic	osteoblastic	ADJ
dti-1338	138	32	differentiation	differentiation	NOUN
dti-1338	138	33	.	.	PUNCT
dti-1338	139	1	discussion	discussion	NOUN
dti-1338	139	2	vpa	vpa	PROPN
dti-1338	139	3	is	be	AUX
dti-1338	139	4	an	an	DET
dti-1338	139	5	effective	effective	ADJ
dti-1338	139	6	and	and	CCONJ
dti-1338	139	7	widely	widely	ADV
dti-1338	139	8	used	use	VERB
dti-1338	139	9	antiepileptic	antiepileptic	ADJ
dti-1338	139	10	and	and	CCONJ
dti-1338	139	11	anticonvulsant	anticonvulsant	ADJ
dti-1338	139	12	drug	drug	NOUN
dti-1338	139	13	which	which	PRON
dti-1338	139	14	influences	influence	VERB
dti-1338	139	15	osteogenesis	osteogenesis	NOUN
dti-1338	139	16	in	in	ADP
dti-1338	139	17	vivo	vivo	NOUN
dti-1338	139	18	and	and	CCONJ
dti-1338	139	19	in	in	ADP
dti-1338	139	20	vitro.1–3	vitro.1–3	NOUN
dti-1338	139	21	in	in	ADP
dti-1338	139	22	terms	term	NOUN
dti-1338	139	23	of	of	ADP
dti-1338	139	24	osteogenesis	osteogenesis	NOUN
dti-1338	139	25	,	,	PUNCT
dti-1338	139	26	osteoblasts	osteoblast	NOUN
dti-1338	139	27	play	play	VERB
dti-1338	139	28	a	a	DET
dti-1338	139	29	critical	critical	ADJ
dti-1338	139	30	role	role	NOUN
dti-1338	139	31	in	in	ADP
dti-1338	139	32	cooperating	cooperate	VERB
dti-1338	139	33	with	with	ADP
dti-1338	139	34	various	various	ADJ
dti-1338	139	35	types	type	NOUN
dti-1338	139	36	of	of	ADP
dti-1338	139	37	cells	cell	NOUN
dti-1338	139	38	,	,	PUNCT
dti-1338	139	39	which	which	PRON
dti-1338	139	40	are	be	AUX
dti-1338	139	41	all	all	PRON
dti-1338	139	42	derived	derive	VERB
dti-1338	139	43	from	from	ADP
dti-1338	139	44	mesenchymal	mesenchymal	ADJ
dti-1338	139	45	stem	stem	NOUN
dti-1338	139	46	cells	cell	NOUN
dti-1338	139	47	.	.	PUNCT
dti-1338	140	1	the	the	DET
dti-1338	140	2	murine	murine	ADJ
dti-1338	140	3	embryonic	embryonic	ADJ
dti-1338	140	4	mesenchymal	mesenchymal	ADJ
dti-1338	140	5	cell	cell	NOUN
dti-1338	140	6	line	line	NOUN
dti-1338	140	7	,	,	PUNCT
dti-1338	140	8	c3h10t1/2	c3h10t1/2	PROPN
dti-1338	140	9	,	,	PUNCT
dti-1338	140	10	is	be	AUX
dti-1338	140	11	a	a	DET
dti-1338	140	12	pluripotent	pluripotent	ADJ
dti-1338	140	13	cell	cell	NOUN
dti-1338	140	14	line	line	NOUN
dti-1338	140	15	which	which	PRON
dti-1338	140	16	can	can	AUX
dti-1338	140	17	be	be	AUX
dti-1338	140	18	differentiated	differentiate	VERB
dti-1338	140	19	into	into	ADP
dti-1338	140	20	osteoblasts	osteoblast	NOUN
dti-1338	140	21	,	,	PUNCT
dti-1338	140	22	chondrocytes	chondrocyte	NOUN
dti-1338	140	23	,	,	PUNCT
dti-1338	140	24	adipocytes	adipocyte	NOUN
dti-1338	140	25	,	,	PUNCT
dti-1338	140	26	and	and	CCONJ
dti-1338	140	27	myoblasts	myoblast	NOUN
dti-1338	140	28	in	in	ADP
dti-1338	140	29	vitro	vitro	X
dti-1338	140	30	and	and	CCONJ
dti-1338	140	31	is	be	AUX
dti-1338	140	32	used	use	VERB
dti-1338	140	33	in	in	ADP
dti-1338	140	34	numerous	numerous	ADJ
dti-1338	140	35	studies	study	NOUN
dti-1338	140	36	as	as	ADP
dti-1338	140	37	a	a	DET
dti-1338	140	38	model	model	NOUN
dti-1338	140	39	for	for	ADP
dti-1338	140	40	mesenchymal	mesenchymal	NOUN
dti-1338	140	41	cell	cell	NOUN
dti-1338	140	42	differentiation.6–8	differentiation.6–8	NOUN
dti-1338	140	43	ecms	ecms	NOUN
dti-1338	140	44	secreted	secrete	VERB
dti-1338	140	45	by	by	ADP
dti-1338	140	46	mesenchymal	mesenchymal	ADJ
dti-1338	140	47	cells	cell	NOUN
dti-1338	140	48	,	,	PUNCT
dti-1338	140	49	including	include	VERB
dti-1338	140	50	osteoblasts	osteoblast	NOUN
dti-1338	140	51	,	,	PUNCT
dti-1338	140	52	also	also	ADV
dti-1338	140	53	play	play	VERB
dti-1338	140	54	a	a	DET
dti-1338	140	55	critical	critical	ADJ
dti-1338	140	56	role	role	NOUN
dti-1338	140	57	in	in	ADP
dti-1338	140	58	osteogenesis	osteogenesis	NOUN
dti-1338	140	59	,	,	PUNCT
dti-1338	140	60	and	and	CCONJ
dti-1338	140	61	two	two	NUM
dti-1338	140	62	ecm	ecm	NOUN
dti-1338	140	63	components	component	NOUN
dti-1338	140	64	,	,	PUNCT
dti-1338	140	65	type	type	VERB
dti-1338	140	66	i	i	PRON
dti-1338	140	67	collagen	collagen	NOUN
dti-1338	140	68	and	and	CCONJ
dti-1338	140	69	fibronectin	fibronectin	NOUN
dti-1338	140	70	,	,	PUNCT
dti-1338	140	71	are	be	AUX
dti-1338	140	72	known	know	VERB
dti-1338	140	73	to	to	PART
dti-1338	140	74	effect	effect	VERB
dti-1338	140	75	osteogenic	osteogenic	ADJ
dti-1338	140	76	cell	cell	NOUN
dti-1338	140	77	proliferation	proliferation	NOUN
dti-1338	140	78	and	and	CCONJ
dti-1338	140	79	differentiation	differentiation	NOUN
dti-1338	140	80	both	both	PRON
dti-1338	140	81	in	in	ADP
dti-1338	140	82	vivo	vivo	NOUN
dti-1338	140	83	and	and	CCONJ
dti-1338	140	84	in	in	ADP
dti-1338	140	85	vitro.10–13	vitro.10–13	NOUN
dti-1338	140	86	in	in	ADP
dti-1338	140	87	this	this	DET
dti-1338	140	88	study	study	NOUN
dti-1338	140	89	,	,	PUNCT
dti-1338	140	90	we	we	PRON
dti-1338	140	91	attempted	attempt	VERB
dti-1338	140	92	to	to	PART
dti-1338	140	93	examine	examine	VERB
dti-1338	140	94	the	the	DET
dti-1338	140	95	effect	effect	NOUN
dti-1338	140	96	of	of	ADP
dti-1338	140	97	vpa	vpa	PROPN
dti-1338	140	98	in	in	ADP
dti-1338	140	99	mesenchymal	mesenchymal	NOUN
dti-1338	140	100	cell	cell	NOUN
dti-1338	140	101	proliferation	proliferation	NOUN
dti-1338	140	102	and	and	CCONJ
dti-1338	140	103	cell	cell	NOUN
dti-1338	140	104	differentiation	differentiation	NOUN
dti-1338	140	105	in	in	ADP
dti-1338	140	106	vitro	vitro	X
dti-1338	140	107	in	in	ADP
dti-1338	140	108	both	both	CCONJ
dti-1338	140	109	the	the	DET
dti-1338	140	110	presence	presence	NOUN
dti-1338	140	111	and	and	CCONJ
dti-1338	140	112	absence	absence	NOUN
dti-1338	140	113	of	of	ADP
dti-1338	140	114	ecms	ecms	NOUN
dti-1338	140	115	.	.	PUNCT
dti-1338	141	1	first	first	ADV
dti-1338	141	2	we	we	PRON
dti-1338	141	3	observed	observe	VERB
dti-1338	141	4	that	that	SCONJ
dti-1338	141	5	normal	normal	ADJ
dti-1338	141	6	cell	cell	NOUN
dti-1338	141	7	shape	shape	NOUN
dti-1338	141	8	was	be	AUX
dti-1338	141	9	maintained	maintain	VERB
dti-1338	141	10	,	,	PUNCT
dti-1338	141	11	but	but	CCONJ
dti-1338	141	12	a	a	DET
dti-1338	141	13	large	large	ADJ
dti-1338	141	14	number	number	NOUN
dti-1338	141	15	of	of	ADP
dti-1338	141	16	stress	stress	NOUN
dti-1338	141	17	fibers	fiber	NOUN
dti-1338	141	18	were	be	AUX
dti-1338	141	19	formed	form	VERB
dti-1338	141	20	in	in	ADP
dti-1338	141	21	high	high	ADJ
dti-1338	141	22	concentrations	concentration	NOUN
dti-1338	141	23	of	of	ADP
dti-1338	141	24	vpa	vpa	PROPN
dti-1338	141	25	after	after	ADP
dti-1338	141	26	a	a	DET
dti-1338	141	27	48	48	NUM
dti-1338	141	28	-	-	PUNCT
dti-1338	141	29	hour	hour	NOUN
dti-1338	141	30	culture	culture	NOUN
dti-1338	141	31	.	.	PUNCT
dti-1338	142	1	previous	previous	ADJ
dti-1338	142	2	studies	study	NOUN
dti-1338	142	3	have	have	AUX
dti-1338	142	4	reported	report	VERB
dti-1338	142	5	that	that	SCONJ
dti-1338	142	6	high	high	ADJ
dti-1338	142	7	concentrations	concentration	NOUN
dti-1338	142	8	of	of	ADP
dti-1338	142	9	vpa	vpa	PROPN
dti-1338	142	10	induced	induce	VERB
dti-1338	142	11	morphological	morphological	ADJ
dti-1338	142	12	changes	change	NOUN
dti-1338	142	13	in	in	ADP
dti-1338	142	14	mouse	mouse	NOUN
dti-1338	142	15	osteoblast	osteoblast	ADJ
dti-1338	142	16	cell	cell	NOUN
dti-1338	142	17	line	line	NOUN
dti-1338	143	1	mc3t3	mc3t3	NOUN
dti-1338	143	2	-	-	PUNCT
dti-1338	143	3	e1	e1	ADJ
dti-1338	143	4	cells4	cells4	NOUN
dti-1338	143	5	and	and	CCONJ
dti-1338	143	6	mouse	mouse	NOUN
dti-1338	143	7	fibroblast	fibroblast	ADJ
dti-1338	143	8	cell	cell	NOUN
dti-1338	143	9	line	line	NOUN
dti-1338	143	10	l929.17	l929.17	ADJ
dti-1338	143	11	microarray	microarray	NOUN
dti-1338	143	12	analysis	analysis	NOUN
dti-1338	143	13	of	of	ADP
dti-1338	143	14	somatic	somatic	ADJ
dti-1338	143	15	tissue	tissue	NOUN
dti-1338	143	16	of	of	ADP
dti-1338	143	17	mouse	mouse	NOUN
dti-1338	143	18	embryos	embryo	NOUN
dti-1338	143	19	with	with	ADP
dti-1338	143	20	applied	apply	VERB
dti-1338	143	21	vpa	vpa	PROPN
dti-1338	143	22	revealed	reveal	VERB
dti-1338	143	23	that	that	SCONJ
dti-1338	143	24	gene	gene	NOUN
dti-1338	143	25	expression	expression	NOUN
dti-1338	143	26	in	in	ADP
dti-1338	143	27	the	the	DET
dti-1338	143	28	microtubule	microtubule	NOUN
dti-1338	143	29	cytoskeleton	cytoskeleton	NOUN
dti-1338	143	30	and	and	CCONJ
dti-1338	143	31	actin	actin	NOUN
dti-1338	143	32	filament	filament	NOUN
dti-1338	143	33	may	may	AUX
dti-1338	143	34	be	be	AUX
dti-1338	143	35	associated	associate	VERB
dti-1338	143	36	with	with	ADP
dti-1338	143	37	axis	axis	ADJ
dti-1338	143	38	skeletal	skeletal	ADJ
dti-1338	143	39	malformations2	malformations2	NOUN
dti-1338	143	40	and	and	CCONJ
dti-1338	143	41	increasing	increase	VERB
dti-1338	143	42	levels	level	NOUN
dti-1338	143	43	of	of	ADP
dti-1338	143	44	f	f	PROPN
dti-1338	143	45	-	-	PUNCT
dti-1338	143	46	actin	actin	NOUN
dti-1338	143	47	were	be	AUX
dti-1338	143	48	also	also	ADV
dti-1338	143	49	observed	observe	VERB
dti-1338	143	50	in	in	ADP
dti-1338	143	51	mouse	mouse	PROPN
dti-1338	143	52	fibroblasts.17	fibroblasts.17	NOUN
dti-1338	143	53	our	our	PRON
dti-1338	143	54	observations	observation	NOUN
dti-1338	143	55	on	on	ADP
dti-1338	143	56	the	the	DET
dti-1338	143	57	morphology	morphology	NOUN
dti-1338	143	58	of	of	ADP
dti-1338	143	59	undifferentiated	undifferentiated	ADJ
dti-1338	143	60	mesenchymal	mesenchymal	NOUN
dti-1338	143	61	cells	cell	NOUN
dti-1338	143	62	cultured	culture	VERB
dti-1338	143	63	in	in	ADP
dti-1338	143	64	a	a	DET
dti-1338	143	65	vpa	vpa	PROPN
dti-1338	143	66	-	-	PUNCT
dti-1338	143	67	containing	contain	VERB
dti-1338	143	68	medium	medium	NOUN
dti-1338	143	69	is	be	AUX
dti-1338	143	70	consistent	consistent	ADJ
dti-1338	143	71	with	with	ADP
dti-1338	143	72	these	these	DET
dti-1338	143	73	reports	report	NOUN
dti-1338	143	74	and	and	CCONJ
dti-1338	143	75	suggests	suggest	VERB
dti-1338	143	76	that	that	SCONJ
dti-1338	143	77	vpa	vpa	PROPN
dti-1338	143	78	could	could	AUX
dti-1338	143	79	rearrange	rearrange	VERB
dti-1338	143	80	the	the	DET
dti-1338	143	81	cytoskeleton	cytoskeleton	NOUN
dti-1338	143	82	of	of	ADP
dti-1338	143	83	various	various	ADJ
dti-1338	143	84	types	type	NOUN
dti-1338	143	85	of	of	ADP
dti-1338	143	86	cells	cell	NOUN
dti-1338	143	87	.	.	PUNCT
dti-1338	144	1	in	in	ADP
dti-1338	144	2	the	the	DET
dti-1338	144	3	cell	cell	NOUN
dti-1338	144	4	proliferation	proliferation	NOUN
dti-1338	144	5	on	on	ADP
dti-1338	144	6	a	a	DET
dti-1338	144	7	non	non	ADJ
dti-1338	144	8	-	-	ADJ
dti-1338	144	9	coated	coated	ADJ
dti-1338	144	10	plastic	plastic	NOUN
dti-1338	144	11	plate	plate	NOUN
dti-1338	144	12	,	,	PUNCT
dti-1338	144	13	our	our	PRON
dti-1338	144	14	results	result	NOUN
dti-1338	144	15	showed	show	VERB
dti-1338	144	16	that	that	SCONJ
dti-1338	144	17	mesenchymal	mesenchymal	NOUN
dti-1338	144	18	cells	cell	NOUN
dti-1338	144	19	were	be	AUX
dti-1338	144	20	positive	positive	ADJ
dti-1338	144	21	for	for	ADP
dti-1338	144	22	pcna	pcna	NOUN
dti-1338	144	23	at	at	ADP
dti-1338	144	24	all	all	DET
dti-1338	144	25	vpa	vpa	PROPN
dti-1338	144	26	concentrations	concentration	NOUN
dti-1338	144	27	,	,	PUNCT
dti-1338	144	28	from	from	ADP
dti-1338	144	29	1	1	NUM
dti-1338	144	30	to	to	ADP
dti-1338	144	31	1000	1000	NUM
dti-1338	144	32	µg	µg	NOUN
dti-1338	144	33	/	/	SYM
dti-1338	144	34	ml	ml	NOUN
dti-1338	144	35	,	,	PUNCT
dti-1338	144	36	after	after	ADP
dti-1338	144	37	48	48	NUM
dti-1338	144	38	hours	hour	NOUN
dti-1338	144	39	and	and	CCONJ
dti-1338	144	40	we	we	PRON
dti-1338	144	41	detected	detect	VERB
dti-1338	144	42	no	no	DET
dti-1338	144	43	significant	significant	ADJ
dti-1338	144	44	differences	difference	NOUN
dti-1338	144	45	between	between	ADP
dti-1338	144	46	the	the	DET
dti-1338	144	47	control	control	NOUN
dti-1338	144	48	(	(	PUNCT
dti-1338	144	49	0	0	NUM
dti-1338	144	50	µg	µg	NOUN
dti-1338	144	51	/	/	SYM
dti-1338	144	52	ml	ml	NOUN
dti-1338	144	53	)	)	PUNCT
dti-1338	144	54	and	and	CCONJ
dti-1338	144	55	100	100	NUM
dti-1338	144	56	µg	µg	ADJ
dti-1338	144	57	/	/	SYM
dti-1338	144	58	ml	ml	NOUN
dti-1338	144	59	populations	population	NOUN
dti-1338	144	60	cultured	culture	VERB
dti-1338	144	61	for	for	ADP
dti-1338	144	62	48	48	NUM
dti-1338	144	63	hours	hour	NOUN
dti-1338	144	64	when	when	SCONJ
dti-1338	144	65	pcna	pcna	X
dti-1338	144	66	-	-	PUNCT
dti-1338	144	67	positive	positive	ADJ
dti-1338	144	68	cell	cell	NOUN
dti-1338	144	69	counts	count	NOUN
dti-1338	144	70	were	be	AUX
dti-1338	144	71	obtained	obtain	VERB
dti-1338	144	72	from	from	ADP
dti-1338	144	73	a	a	DET
dti-1338	144	74	randomly	randomly	ADV
dti-1338	144	75	chosen	choose	VERB
dti-1338	144	76	area	area	NOUN
dti-1338	144	77	and	and	CCONJ
dti-1338	144	78	also	also	ADV
dti-1338	144	79	when	when	SCONJ
dti-1338	144	80	the	the	DET
dti-1338	144	81	estimated	estimate	VERB
dti-1338	144	82	cell	cell	NOUN
dti-1338	144	83	number	number	NOUN
dti-1338	144	84	was	be	AUX
dti-1338	144	85	determined	determine	VERB
dti-1338	144	86	from	from	ADP
dti-1338	144	87	an	an	DET
dti-1338	144	88	assay	assay	NOUN
dti-1338	144	89	utilizing	utilize	VERB
dti-1338	144	90	watersoluble	watersoluble	ADJ
dti-1338	144	91	formazan	formazan	PROPN
dti-1338	144	92	dye	dye	PROPN
dti-1338	144	93	.	.	PUNCT
dti-1338	145	1	previous	previous	ADJ
dti-1338	145	2	studies	study	NOUN
dti-1338	145	3	were	be	AUX
dti-1338	145	4	performed	perform	VERB
dti-1338	145	5	at	at	ADP
dti-1338	145	6	0.1	0.1	NUM
dti-1338	145	7	µm	µm	NOUN
dti-1338	145	8	to	to	ADP
dti-1338	145	9	3	3	NUM
dti-1338	145	10	mm	mm	NOUN
dti-1338	145	11	vpa	vpa	PROPN
dti-1338	145	12	concentrations	concentration	NOUN
dti-1338	145	13	(	(	PUNCT
dti-1338	145	14	corresponding	correspond	VERB
dti-1338	145	15	to	to	ADP
dti-1338	145	16	0.08	0.08	NUM
dti-1338	145	17	to	to	PART
dti-1338	145	18	480	480	NUM
dti-1338	145	19	µg	µg	ADJ
dti-1338	145	20	/	/	SYM
dti-1338	145	21	ml	ml	NOUN
dti-1338	145	22	values	value	NOUN
dti-1338	145	23	)	)	PUNCT
dti-1338	145	24	for	for	ADP
dti-1338	145	25	cell	cell	NOUN
dti-1338	145	26	viability	viability	NOUN
dti-1338	145	27	and	and	CCONJ
dti-1338	145	28	proliferation	proliferation	NOUN
dti-1338	145	29	assays	assay	NOUN
dti-1338	145	30	in	in	ADP
dti-1338	145	31	osteoblasts	osteoblast	NOUN
dti-1338	145	32	and	and	CCONJ
dti-1338	145	33	neural	neural	ADJ
dti-1338	145	34	crest	crest	NOUN
dti-1338	145	35	cells.4,18	cells.4,18	NOUN
dti-1338	145	36	in	in	ADP
dti-1338	145	37	a	a	DET
dti-1338	145	38	mouse	mouse	NOUN
dti-1338	145	39	osteoblast	osteoblast	ADJ
dti-1338	145	40	cell	cell	NOUN
dti-1338	145	41	line	line	NOUN
dti-1338	145	42	,	,	PUNCT
dti-1338	145	43	mc3t3	mc3t3	NOUN
dti-1338	145	44	-	-	NOUN
dti-1338	145	45	e1	e1	NOUN
dti-1338	145	46	,	,	PUNCT
dti-1338	145	47	vpa	vpa	PROPN
dti-1338	145	48	promoted	promote	VERB
dti-1338	145	49	cell	cell	NOUN
dti-1338	145	50	proliferation	proliferation	NOUN
dti-1338	145	51	at	at	ADP
dti-1338	145	52	low	low	ADJ
dti-1338	145	53	concentrations	concentration	NOUN
dti-1338	145	54	of	of	ADP
dti-1338	145	55	0.1	0.1	NUM
dti-1338	145	56	to	to	PART
dti-1338	145	57	50	50	NUM
dti-1338	145	58	µm	µm	NOUN
dti-1338	145	59	(	(	PUNCT
dti-1338	145	60	corresponding	correspond	VERB
dti-1338	145	61	to	to	ADP
dti-1338	145	62	0.08	0.08	NUM
dti-1338	145	63	to	to	PART
dti-1338	145	64	4	4	NUM
dti-1338	145	65	µg	µg	ADV
dti-1338	145	66	/	/	SYM
dti-1338	145	67	ml	ml	NOUN
dti-1338	145	68	values	value	NOUN
dti-1338	145	69	)	)	PUNCT
dti-1338	145	70	and	and	CCONJ
dti-1338	145	71	decreased	decrease	VERB
dti-1338	145	72	the	the	DET
dti-1338	145	73	cell	cell	NOUN
dti-1338	145	74	proliferation	proliferation	NOUN
dti-1338	145	75	rate	rate	NOUN
dti-1338	145	76	at	at	ADP
dti-1338	145	77	a	a	DET
dti-1338	145	78	high	high	ADJ
dti-1338	145	79	concentration	concentration	NOUN
dti-1338	145	80	of	of	ADP
dti-1338	145	81	1	1	NUM
dti-1338	145	82	mm.4	mm.4	NOUN
dti-1338	145	83	on	on	ADP
dti-1338	145	84	the	the	DET
dti-1338	145	85	other	other	ADJ
dti-1338	145	86	hand	hand	NOUN
dti-1338	145	87	,	,	PUNCT
dti-1338	145	88	neural	neural	ADJ
dti-1338	145	89	crest	crest	NOUN
dti-1338	145	90	cells	cell	NOUN
dti-1338	145	91	could	could	AUX
dti-1338	145	92	proliferate	proliferate	VERB
dti-1338	145	93	at	at	ADP
dti-1338	145	94	1.5	1.5	NUM
dti-1338	145	95	mm	mm	NOUN
dti-1338	145	96	(	(	PUNCT
dti-1338	145	97	240	240	NUM
dti-1338	145	98	µg	µg	NOUN
dti-1338	145	99	/	/	SYM
dti-1338	145	100	ml	ml	NOUN
dti-1338	145	101	)	)	PUNCT
dti-1338	145	102	concentrations	concentration	NOUN
dti-1338	145	103	of	of	ADP
dti-1338	145	104	vpa	vpa	PROPN
dti-1338	145	105	and	and	CCONJ
dti-1338	145	106	this	this	PRON
dti-1338	145	107	was	be	AUX
dti-1338	145	108	not	not	PART
dti-1338	145	109	significantly	significantly	ADV
dti-1338	145	110	different	different	ADJ
dti-1338	145	111	to	to	ADP
dti-1338	145	112	the	the	DET
dti-1338	145	113	control	control	NOUN
dti-1338	145	114	results.18	results.18	NOUN
dti-1338	145	115	taken	take	VERB
dti-1338	145	116	together	together	ADV
dti-1338	145	117	,	,	PUNCT
dti-1338	145	118	our	our	PRON
dti-1338	145	119	data	datum	NOUN
dti-1338	145	120	suggested	suggest	VERB
dti-1338	145	121	that	that	SCONJ
dti-1338	145	122	the	the	DET
dti-1338	145	123	effect	effect	NOUN
dti-1338	145	124	of	of	ADP
dti-1338	145	125	vpa	vpa	PROPN
dti-1338	145	126	on	on	ADP
dti-1338	145	127	cell	cell	NOUN
dti-1338	145	128	proliferation	proliferation	NOUN
dti-1338	145	129	is	be	AUX
dti-1338	145	130	dependent	dependent	ADJ
dti-1338	145	131	on	on	ADP
dti-1338	145	132	the	the	DET
dti-1338	145	133	maturation	maturation	NOUN
dti-1338	145	134	level	level	NOUN
dti-1338	145	135	of	of	ADP
dti-1338	145	136	the	the	DET
dti-1338	145	137	cells	cell	NOUN
dti-1338	145	138	,	,	PUNCT
dti-1338	145	139	namely	namely	ADV
dti-1338	145	140	that	that	DET
dti-1338	145	141	immature	immature	ADJ
dti-1338	145	142	cells	cell	NOUN
dti-1338	145	143	have	have	VERB
dti-1338	145	144	resistance	resistance	NOUN
dti-1338	145	145	to	to	ADP
dti-1338	145	146	high	high	ADJ
dti-1338	145	147	concentrations	concentration	NOUN
dti-1338	145	148	of	of	ADP
dti-1338	145	149	vpa	vpa	PROPN
dti-1338	145	150	.	.	PUNCT
dti-1338	146	1	in	in	ADP
dti-1338	146	2	the	the	DET
dti-1338	146	3	present	present	ADJ
dti-1338	146	4	study	study	NOUN
dti-1338	146	5	,	,	PUNCT
dti-1338	146	6	vpa	vpa	PROPN
dti-1338	146	7	had	have	VERB
dti-1338	146	8	inhibitory	inhibitory	ADJ
dti-1338	146	9	effect	effect	NOUN
dti-1338	146	10	on	on	ADP
dti-1338	146	11	the	the	DET
dti-1338	146	12	mesenchymal	mesenchymal	NOUN
dti-1338	146	13	cell	cell	NOUN
dti-1338	146	14	proliferation	proliferation	NOUN
dti-1338	146	15	with	with	ADP
dti-1338	146	16	culture	culture	NOUN
dti-1338	146	17	on	on	ADP
dti-1338	146	18	an	an	DET
dti-1338	146	19	ecm	ecm	NOUN
dti-1338	146	20	coat	coat	NOUN
dti-1338	146	21	of	of	ADP
dti-1338	146	22	fibronectin	fibronectin	NOUN
dti-1338	146	23	and	and	CCONJ
dti-1338	146	24	type	type	NOUN
dti-1338	146	25	i	i	PRON
dti-1338	146	26	collagen	collagen	NOUN
dti-1338	146	27	.	.	PUNCT
dti-1338	147	1	fibronectin	fibronectin	NOUN
dti-1338	147	2	and	and	CCONJ
dti-1338	147	3	type	type	NOUN
dti-1338	148	1	i	i	PRON
dti-1338	148	2	collagen	collagen	NOUN
dti-1338	148	3	are	be	AUX
dti-1338	148	4	major	major	ADJ
dti-1338	148	5	components	component	NOUN
dti-1338	148	6	of	of	ADP
dti-1338	148	7	ecms	ecms	NOUN
dti-1338	148	8	and	and	CCONJ
dti-1338	148	9	well	well	ADV
dti-1338	148	10	known	know	VERB
dti-1338	148	11	to	to	PART
dti-1338	148	12	promote	promote	VERB
dti-1338	148	13	mesenchymal	mesenchymal	ADJ
dti-1338	148	14	cell	cell	NOUN
dti-1338	148	15	proliferation.10–19	proliferation.10–19	NOUN
dti-1338	148	16	consist	consist	VERB
dti-1338	148	17	with	with	ADP
dti-1338	148	18	these	these	DET
dti-1338	148	19	reports	report	NOUN
dti-1338	148	20	,	,	PUNCT
dti-1338	148	21	our	our	PRON
dti-1338	148	22	data	datum	NOUN
dti-1338	148	23	showed	show	VERB
dti-1338	148	24	that	that	SCONJ
dti-1338	148	25	fibronectin	fibronectin	NOUN
dti-1338	148	26	or	or	CCONJ
dti-1338	148	27	type	type	NOUN
dti-1338	148	28	i	i	PRON
dti-1338	148	29	alone	alone	ADV
dti-1338	148	30	had	have	VERB
dti-1338	148	31	the	the	DET
dti-1338	148	32	effect	effect	NOUN
dti-1338	148	33	of	of	ADP
dti-1338	148	34	increasing	increase	VERB
dti-1338	148	35	cell	cell	NOUN
dti-1338	148	36	proliferation	proliferation	NOUN
dti-1338	148	37	in	in	ADP
dti-1338	148	38	the	the	DET
dti-1338	148	39	absence	absence	NOUN
dti-1338	148	40	http://www.la-press.com	http://www.la-press.com	X
dti-1338	149	1	the	the	DET
dti-1338	149	2	effect	effect	NOUN
dti-1338	149	3	of	of	ADP
dti-1338	149	4	vpa	vpa	PROPN
dti-1338	149	5	on	on	ADP
dti-1338	149	6	mesenchymal	mesenchymal	ADJ
dti-1338	149	7	cell	cell	NOUN
dti-1338	149	8	in	in	ADP
dti-1338	149	9	ecm	ecm	PROPN
dti-1338	149	10	drug	drug	NOUN
dti-1338	149	11	target	target	NOUN
dti-1338	149	12	insights	insight	NOUN
dti-1338	149	13	2011:5	2011:5	NUM
dti-1338	149	14	7	7	NUM
dti-1338	149	15	collagen	collagen	NOUN
dti-1338	149	16	1α2	1α2	NUM
dti-1338	149	17	gapdh	gapdh	NOUN
dti-1338	149	18	gapdh	gapdh	NOUN
dti-1338	149	19	gapdh	gapdh	NOUN
dti-1338	149	20	gapdh	gapdh	NOUN
dti-1338	149	21	normal	normal	ADJ
dti-1338	149	22	collagen	collagen	NOUN
dti-1338	149	23	normal	normal	ADJ
dti-1338	149	24	collagen	collagen	NOUN
dti-1338	149	25	normal	normal	ADJ
dti-1338	149	26	collagen	collagen	NOUN
dti-1338	149	27	normal	normal	ADJ
dti-1338	149	28	collagen	collagen	NOUN
dti-1338	149	29	control	control	NOUN
dti-1338	149	30	a	a	DET
dti-1338	149	31	col1α	col1α	PROPN
dti-1338	149	32	2	2	NUM
dti-1338	149	33	osteopontinb	osteopontinb	ADJ
dti-1338	149	34	opn	opn	PROPN
dti-1338	149	35	bspc	bspc	PROPN
dti-1338	149	36	bsp	bsp	VERB
dti-1338	149	37	oc	oc	ADP
dti-1338	149	38	osteocalcind	osteocalcind	PROPN
dti-1338	149	39	*	*	PUNCT
dti-1338	150	1	*	*	PUNCT
dti-1338	151	1	*	*	PUNCT
dti-1338	152	1	*	*	PUNCT
dti-1338	153	1	*	*	PUNCT
dti-1338	154	1	*	*	PUNCT
dti-1338	155	1	*	*	PUNCT
dti-1338	156	1	*	*	PUNCT
dti-1338	157	1	*	*	PUNCT
dti-1338	158	1	*	*	PUNCT
dti-1338	159	1	*	*	PUNCT
dti-1338	160	1	*	*	PUNCT
dti-1338	161	1	*	*	PUNCT
dti-1338	162	1	*	*	PUNCT
dti-1338	163	1	*	*	PUNCT
dti-1338	164	1	*	*	PUNCT
dti-1338	165	1	*	*	PUNCT
dti-1338	166	1	*	*	PUNCT
dti-1338	167	1	*	*	PUNCT
dti-1338	167	2	*	*	PUNCT
dti-1338	167	3	1.0	1.0	NUM
dti-1338	167	4	0.9	0.9	NUM
dti-1338	167	5	0.8	0.8	NUM
dti-1338	167	6	0.7	0.7	NUM
dti-1338	167	7	0.6	0.6	NUM
dti-1338	167	8	0.5	0.5	NUM
dti-1338	167	9	0.4	0.4	NUM
dti-1338	167	10	0.3	0.3	NUM
dti-1338	167	11	0.2	0.2	NUM
dti-1338	167	12	0.1	0.1	NUM
dti-1338	167	13	1.0	1.0	NUM
dti-1338	167	14	0.9	0.9	NUM
dti-1338	167	15	0.8	0.8	NUM
dti-1338	167	16	0.7	0.7	NUM
dti-1338	167	17	0.6	0.6	NUM
dti-1338	167	18	0.5	0.5	NUM
dti-1338	167	19	0.4	0.4	NUM
dti-1338	167	20	0.3	0.3	NUM
dti-1338	167	21	0.2	0.2	NUM
dti-1338	167	22	0.1	0.1	NUM
dti-1338	167	23	0	0	NUM
dti-1338	167	24	0	0	NUM
dti-1338	167	25	1.0	1.0	NUM
dti-1338	167	26	1.1	1.1	NUM
dti-1338	167	27	0.9	0.9	NUM
dti-1338	167	28	0.8	0.8	NUM
dti-1338	167	29	0.7	0.7	NUM
dti-1338	167	30	0.6	0.6	NUM
dti-1338	167	31	0.5	0.5	NUM
dti-1338	167	32	0.4	0.4	NUM
dti-1338	167	33	0.3	0.3	NUM
dti-1338	167	34	0.2	0.2	NUM
dti-1338	167	35	0.1	0.1	NUM
dti-1338	167	36	0	0	NUM
dti-1338	167	37	1.0	1.0	NUM
dti-1338	167	38	1.1	1.1	NUM
dti-1338	167	39	0.9	0.9	NUM
dti-1338	167	40	0.8	0.8	NUM
dti-1338	167	41	0.7	0.7	NUM
dti-1338	167	42	0.6	0.6	NUM
dti-1338	167	43	0.5	0.5	NUM
dti-1338	167	44	0.4	0.4	NUM
dti-1338	167	45	0.3	0.3	NUM
dti-1338	167	46	0.2	0.2	NUM
dti-1338	167	47	0.1	0.1	NUM
dti-1338	167	48	0	0	NUM
dti-1338	168	1	*	*	PUNCT
dti-1338	169	1	*	*	PUNCT
dti-1338	170	1	*	*	PUNCT
dti-1338	171	1	*	*	PUNCT
dti-1338	171	2	*	*	PUNCT
dti-1338	171	3	*	*	PUNCT
dti-1338	171	4	r	r	X
dti-1338	171	5	el	el	PROPN
dti-1338	171	6	at	at	ADP
dti-1338	171	7	iv	iv	NUM
dti-1338	171	8	e	e	X
dti-1338	171	9	g	g	PROPN
dti-1338	171	10	en	en	X
dti-1338	171	11	e	e	X
dti-1338	171	12	ex	ex	X
dti-1338	171	13	p	p	PROPN
dti-1338	171	14	re	re	ADP
dti-1338	171	15	ss	ss	PROPN
dti-1338	171	16	io	io	PROPN
dti-1338	171	17	n	n	ADV
dti-1338	171	18	n	n	ADV
dti-1338	172	1	o	o	NOUN
dti-1338	172	2	rm	rm	NOUN
dti-1338	172	3	al	al	PROPN
dti-1338	172	4	iz	iz	INTJ
dti-1338	173	1	ed	ed	PROPN
dti-1338	173	2	t	t	PROPN
dti-1338	173	3	o	o	INTJ
dti-1338	174	1	g	g	PROPN
dti-1338	174	2	a	a	DET
dti-1338	174	3	p	p	X
dti-1338	174	4	d	d	X
dti-1338	174	5	h	h	NOUN
dti-1338	174	6	r	r	NOUN
dti-1338	174	7	el	el	PROPN
dti-1338	174	8	at	at	ADP
dti-1338	174	9	iv	iv	NUM
dti-1338	174	10	e	e	X
dti-1338	174	11	g	g	PROPN
dti-1338	174	12	en	en	X
dti-1338	174	13	e	e	X
dti-1338	174	14	ex	ex	X
dti-1338	174	15	p	p	PROPN
dti-1338	174	16	re	re	ADP
dti-1338	174	17	ss	ss	PROPN
dti-1338	174	18	io	io	PROPN
dti-1338	174	19	n	n	ADV
dti-1338	174	20	n	n	ADV
dti-1338	174	21	o	o	NOUN
dti-1338	174	22	rm	rm	NOUN
dti-1338	175	1	al	al	PROPN
dti-1338	175	2	iz	iz	INTJ
dti-1338	176	1	ed	ed	PROPN
dti-1338	176	2	t	t	PROPN
dti-1338	176	3	o	o	INTJ
dti-1338	177	1	g	g	PROPN
dti-1338	177	2	a	a	DET
dti-1338	177	3	p	p	X
dti-1338	177	4	d	d	X
dti-1338	177	5	h	h	NOUN
dti-1338	177	6	r	r	NOUN
dti-1338	177	7	el	el	PROPN
dti-1338	177	8	at	at	ADP
dti-1338	177	9	iv	iv	NUM
dti-1338	177	10	e	e	X
dti-1338	177	11	g	g	PROPN
dti-1338	177	12	en	en	X
dti-1338	177	13	e	e	X
dti-1338	177	14	ex	ex	X
dti-1338	177	15	p	p	PROPN
dti-1338	177	16	re	re	ADP
dti-1338	177	17	ss	ss	PROPN
dti-1338	177	18	io	io	PROPN
dti-1338	177	19	n	n	ADV
dti-1338	177	20	n	n	ADV
dti-1338	177	21	o	o	NOUN
dti-1338	177	22	rm	rm	NOUN
dti-1338	178	1	al	al	PROPN
dti-1338	178	2	iz	iz	INTJ
dti-1338	179	1	ed	ed	PROPN
dti-1338	179	2	t	t	PROPN
dti-1338	179	3	o	o	INTJ
dti-1338	180	1	g	g	PROPN
dti-1338	180	2	a	a	DET
dti-1338	180	3	p	p	X
dti-1338	180	4	d	d	X
dti-1338	180	5	h	h	NOUN
dti-1338	180	6	r	r	NOUN
dti-1338	180	7	el	el	PROPN
dti-1338	180	8	at	at	ADP
dti-1338	180	9	iv	iv	NUM
dti-1338	180	10	e	e	X
dti-1338	180	11	g	g	PROPN
dti-1338	180	12	en	en	X
dti-1338	180	13	e	e	X
dti-1338	180	14	ex	ex	X
dti-1338	180	15	p	p	PROPN
dti-1338	180	16	re	re	ADP
dti-1338	180	17	ss	ss	PROPN
dti-1338	180	18	io	io	PROPN
dti-1338	180	19	n	n	ADV
dti-1338	180	20	n	n	ADV
dti-1338	180	21	o	o	NOUN
dti-1338	180	22	rm	rm	NOUN
dti-1338	181	1	al	al	PROPN
dti-1338	181	2	iz	iz	INTJ
dti-1338	182	1	ed	ed	PROPN
dti-1338	182	2	t	t	PROPN
dti-1338	182	3	o	o	INTJ
dti-1338	183	1	g	g	PROPN
dti-1338	183	2	a	a	DET
dti-1338	183	3	p	p	X
dti-1338	183	4	d	d	PROPN
dti-1338	183	5	h	h	PROPN
dti-1338	183	6	vpa	vpa	PROPN
dti-1338	183	7	control	control	PROPN
dti-1338	183	8	vpa	vpa	PROPN
dti-1338	183	9	control	control	PROPN
dti-1338	183	10	vpa	vpa	PROPN
dti-1338	183	11	control	control	PROPN
dti-1338	183	12	vpa	vpa	PROPN
dti-1338	183	13	control	control	PROPN
dti-1338	183	14	vpa	vpa	PROPN
dti-1338	183	15	control	control	PROPN
dti-1338	183	16	vpa	vpa	PROPN
dti-1338	183	17	control	control	PROPN
dti-1338	183	18	vpacontrol	vpacontrol	PROPN
dti-1338	183	19	vpa	vpa	PROPN
dti-1338	183	20	figure	figure	NOUN
dti-1338	183	21	4	4	NUM
dti-1338	183	22	.	.	PUNCT
dti-1338	184	1	vpa	vpa	PROPN
dti-1338	184	2	promoted	promote	VERB
dti-1338	184	3	osteoblastic	osteoblastic	ADJ
dti-1338	184	4	cell	cell	NOUN
dti-1338	184	5	differentiation	differentiation	NOUN
dti-1338	184	6	both	both	CCONJ
dti-1338	184	7	in	in	ADP
dti-1338	184	8	the	the	DET
dti-1338	184	9	absence	absence	NOUN
dti-1338	184	10	or	or	CCONJ
dti-1338	184	11	presence	presence	NOUN
dti-1338	184	12	of	of	ADP
dti-1338	184	13	ecm	ecm	NOUN
dti-1338	184	14	.	.	PUNCT
dti-1338	185	1	mesenchymal	mesenchymal	ADJ
dti-1338	185	2	cells	cell	NOUN
dti-1338	185	3	were	be	AUX
dti-1338	185	4	cultured	cultured	ADJ
dti-1338	185	5	in	in	ADP
dti-1338	185	6	the	the	DET
dti-1338	185	7	absence	absence	NOUN
dti-1338	185	8	(	(	PUNCT
dti-1338	185	9	control	control	NOUN
dti-1338	185	10	)	)	PUNCT
dti-1338	185	11	or	or	CCONJ
dti-1338	185	12	presence	presence	NOUN
dti-1338	185	13	of	of	ADP
dti-1338	185	14	vpa	vpa	PROPN
dti-1338	185	15	(	(	PUNCT
dti-1338	185	16	vpa	vpa	PROPN
dti-1338	185	17	)	)	PUNCT
dti-1338	185	18	on	on	ADP
dti-1338	185	19	a	a	DET
dti-1338	185	20	non	non	ADJ
dti-1338	185	21	-	-	ADJ
dti-1338	185	22	coated	coated	ADJ
dti-1338	185	23	plastic	plastic	NOUN
dti-1338	185	24	plate	plate	NOUN
dti-1338	185	25	(	(	PUNCT
dti-1338	185	26	normal	normal	ADJ
dti-1338	185	27	)	)	PUNCT
dti-1338	185	28	or	or	CCONJ
dti-1338	185	29	type	type	NOUN
dti-1338	185	30	i	i	PRON
dti-1338	185	31	collagen	collagen	NOUN
dti-1338	185	32	-	-	PUNCT
dti-1338	185	33	coated	coated	ADJ
dti-1338	185	34	plate	plate	NOUN
dti-1338	185	35	(	(	PUNCT
dti-1338	185	36	collagen	collagen	NOUN
dti-1338	185	37	)	)	PUNCT
dti-1338	185	38	for	for	ADP
dti-1338	185	39	each	each	PRON
dti-1338	185	40	of	of	ADP
dti-1338	185	41	the	the	DET
dti-1338	185	42	conditions	condition	NOUN
dti-1338	185	43	for	for	ADP
dti-1338	185	44	one	one	NUM
dti-1338	185	45	week	week	NOUN
dti-1338	185	46	.	.	PUNCT
dti-1338	186	1	the	the	DET
dti-1338	186	2	expression	expression	NOUN
dti-1338	186	3	level	level	NOUN
dti-1338	186	4	of	of	ADP
dti-1338	186	5	osteoblastic	osteoblastic	ADJ
dti-1338	186	6	marker	marker	NOUN
dti-1338	186	7	genes	gene	NOUN
dti-1338	186	8	,	,	PUNCT
dti-1338	186	9	collagen	collagen	NOUN
dti-1338	186	10	type	type	NOUN
dti-1338	186	11	1α2	1α2	NUM
dti-1338	186	12	(	(	PUNCT
dti-1338	186	13	col	col	NOUN
dti-1338	186	14	1α2	1α2	NUM
dti-1338	186	15	)	)	PUNCT
dti-1338	186	16	,	,	PUNCT
dti-1338	186	17	osteopontin	osteopontin	PROPN
dti-1338	186	18	(	(	PUNCT
dti-1338	186	19	opn	opn	PROPN
dti-1338	186	20	)	)	PUNCT
dti-1338	186	21	,	,	PUNCT
dti-1338	186	22	bone	bone	NOUN
dti-1338	186	23	sialoprotein	sialoprotein	NOUN
dti-1338	186	24	(	(	PUNCT
dti-1338	186	25	bsp	bsp	NOUN
dti-1338	186	26	)	)	PUNCT
dti-1338	186	27	and	and	CCONJ
dti-1338	186	28	osteocalcin	osteocalcin	PROPN
dti-1338	186	29	(	(	PUNCT
dti-1338	186	30	oc	oc	PROPN
dti-1338	186	31	)	)	PUNCT
dti-1338	186	32	were	be	AUX
dti-1338	186	33	assayed	assay	VERB
dti-1338	186	34	by	by	ADP
dti-1338	186	35	semi	semi	ADJ
dti-1338	186	36	-	-	ADJ
dti-1338	186	37	quantitative	quantitative	ADJ
dti-1338	186	38	rt	rt	ADJ
dti-1338	186	39	-	-	PUNCT
dti-1338	186	40	pcr	pcr	PROPN
dti-1338	186	41	and	and	CCONJ
dti-1338	186	42	each	each	DET
dti-1338	186	43	marker	marker	NOUN
dti-1338	186	44	gene	gene	NOUN
dti-1338	186	45	was	be	AUX
dti-1338	186	46	normalized	normalize	VERB
dti-1338	186	47	against	against	ADP
dti-1338	186	48	gapdh	gapdh	NOUN
dti-1338	186	49	.	.	PUNCT
dti-1338	187	1	on	on	ADP
dti-1338	187	2	both	both	CCONJ
dti-1338	187	3	non	non	ADJ
dti-1338	187	4	-	-	ADJ
dti-1338	187	5	coated	coated	ADJ
dti-1338	187	6	plastic	plastic	NOUN
dti-1338	187	7	(	(	PUNCT
dti-1338	187	8	normal	normal	ADJ
dti-1338	187	9	)	)	PUNCT
dti-1338	187	10	and	and	CCONJ
dti-1338	187	11	collagencoated	collagencoate	VERB
dti-1338	187	12	(	(	PUNCT
dti-1338	187	13	collagen	collagen	NOUN
dti-1338	187	14	)	)	PUNCT
dti-1338	187	15	plates	plate	NOUN
dti-1338	187	16	,	,	PUNCT
dti-1338	187	17	vpa	vpa	PROPN
dti-1338	187	18	promoted	promote	VERB
dti-1338	187	19	the	the	DET
dti-1338	187	20	expression	expression	NOUN
dti-1338	187	21	level	level	NOUN
dti-1338	187	22	of	of	ADP
dti-1338	187	23	each	each	DET
dti-1338	187	24	marker	marker	NOUN
dti-1338	187	25	gene	gene	NOUN
dti-1338	187	26	significantly	significantly	ADV
dti-1338	187	27	compared	compare	VERB
dti-1338	187	28	to	to	ADP
dti-1338	187	29	the	the	DET
dti-1338	187	30	control	control	NOUN
dti-1338	187	31	results	result	NOUN
dti-1338	187	32	(	(	PUNCT
dti-1338	187	33	a	a	DET
dti-1338	187	34	,	,	PUNCT
dti-1338	187	35	b	b	NOUN
dti-1338	187	36	,	,	PUNCT
dti-1338	187	37	d	d	NOUN
dti-1338	187	38	)	)	PUNCT
dti-1338	187	39	,	,	PUNCT
dti-1338	187	40	except	except	SCONJ
dti-1338	187	41	in	in	ADP
dti-1338	187	42	the	the	DET
dti-1338	187	43	case	case	NOUN
dti-1338	187	44	of	of	ADP
dti-1338	187	45	bsp	bsp	NOUN
dti-1338	187	46	(	(	PUNCT
dti-1338	187	47	c	c	NOUN
dti-1338	187	48	)	)	PUNCT
dti-1338	187	49	.	.	PUNCT
dti-1338	188	1	when	when	SCONJ
dti-1338	188	2	comparing	compare	VERB
dti-1338	188	3	normal	normal	ADJ
dti-1338	188	4	and	and	CCONJ
dti-1338	188	5	collagen	collagen	NOUN
dti-1338	188	6	conditions	condition	NOUN
dti-1338	188	7	,	,	PUNCT
dti-1338	188	8	vpa	vpa	PROPN
dti-1338	188	9	significantly	significantly	ADV
dti-1338	188	10	increased	increase	VERB
dti-1338	188	11	marker	marker	NOUN
dti-1338	188	12	gene	gene	NOUN
dti-1338	188	13	levels	level	NOUN
dti-1338	188	14	cultured	cultured	ADJ
dti-1338	188	15	in	in	ADP
dti-1338	188	16	the	the	DET
dti-1338	188	17	latter	latter	ADJ
dti-1338	188	18	(	(	PUNCT
dti-1338	188	19	a	a	DET
dti-1338	188	20	,	,	PUNCT
dti-1338	188	21	b	b	NOUN
dti-1338	188	22	,	,	PUNCT
dti-1338	188	23	d	d	NOUN
dti-1338	188	24	)	)	PUNCT
dti-1338	188	25	,	,	PUNCT
dti-1338	188	26	except	except	SCONJ
dti-1338	188	27	in	in	ADP
dti-1338	188	28	the	the	DET
dti-1338	188	29	case	case	NOUN
dti-1338	188	30	of	of	ADP
dti-1338	188	31	bsp	bsp	NOUN
dti-1338	188	32	(	(	PUNCT
dti-1338	188	33	c	c	NOUN
dti-1338	188	34	)	)	PUNCT
dti-1338	188	35	.	.	PUNCT
dti-1338	189	1	n	n	NOUN
dti-1338	190	1	=	=	SYM
dti-1338	190	2	3	3	NUM
dti-1338	190	3	in	in	ADP
dti-1338	190	4	each	each	DET
dti-1338	190	5	experiment	experiment	NOUN
dti-1338	190	6	group	group	NOUN
dti-1338	190	7	.	.	PUNCT
dti-1338	191	1	notes	note	VERB
dti-1338	191	2	:	:	PUNCT
dti-1338	191	3	*	*	PUNCT
dti-1338	191	4	p	p	NOUN
dti-1338	191	5	,	,	PUNCT
dti-1338	191	6	0.05	0.05	NUM
dti-1338	191	7	;	;	PUNCT
dti-1338	191	8	*	*	PUNCT
dti-1338	191	9	*	*	PUNCT
dti-1338	191	10	p	p	X
dti-1338	191	11	,	,	PUNCT
dti-1338	191	12	0.01	0.01	NUM
dti-1338	191	13	comparing	compare	VERB
dti-1338	191	14	control	control	NOUN
dti-1338	191	15	or	or	CCONJ
dti-1338	191	16	normal	normal	ADJ
dti-1338	191	17	with	with	ADP
dti-1338	191	18	control	control	NOUN
dti-1338	191	19	or	or	CCONJ
dti-1338	191	20	vpa	vpa	PROPN
dti-1338	191	21	.	.	PUNCT
dti-1338	192	1	http://www.la-press.com	http://www.la-press.com	X
dti-1338	192	2	hatakeyama	hatakeyama	PROPN
dti-1338	192	3	et	et	PROPN
dti-1338	192	4	al	al	PROPN
dti-1338	192	5	8	8	NUM
dti-1338	192	6	drug	drug	NOUN
dti-1338	192	7	target	target	NOUN
dti-1338	192	8	insights	insight	NOUN
dti-1338	192	9	2011:5	2011:5	NUM
dti-1338	192	10	of	of	ADP
dti-1338	192	11	vpa	vpa	PROPN
dti-1338	192	12	as	as	SCONJ
dti-1338	192	13	compared	compare	VERB
dti-1338	192	14	with	with	ADP
dti-1338	192	15	normal	normal	ADJ
dti-1338	192	16	culture	culture	NOUN
dti-1338	192	17	.	.	PUNCT
dti-1338	193	1	therefore	therefore	ADV
dti-1338	193	2	inhibitory	inhibitory	ADJ
dti-1338	193	3	effect	effect	NOUN
dti-1338	193	4	of	of	ADP
dti-1338	193	5	vpa	vpa	PROPN
dti-1338	193	6	on	on	ADP
dti-1338	193	7	cell	cell	NOUN
dti-1338	193	8	proliferation	proliferation	NOUN
dti-1338	193	9	in	in	ADP
dti-1338	193	10	the	the	DET
dti-1338	193	11	presence	presence	NOUN
dti-1338	193	12	of	of	ADP
dti-1338	193	13	fibronectin	fibronectin	NOUN
dti-1338	193	14	and	and	CCONJ
dti-1338	193	15	collagen	collagen	NOUN
dti-1338	193	16	type	type	NOUN
dti-1338	193	17	i	i	PRON
dti-1338	193	18	cultured	culture	VERB
dti-1338	193	19	with	with	ADP
dti-1338	193	20	vpa	vpa	PROPN
dti-1338	193	21	may	may	AUX
dti-1338	193	22	be	be	AUX
dti-1338	193	23	depend	depend	VERB
dti-1338	193	24	on	on	ADP
dti-1338	193	25	that	that	DET
dti-1338	193	26	interactions	interaction	NOUN
dti-1338	193	27	between	between	ADP
dti-1338	193	28	mesenchymal	mesenchymal	NOUN
dti-1338	193	29	cells	cell	NOUN
dti-1338	193	30	and	and	CCONJ
dti-1338	193	31	ecm	ecm	NOUN
dti-1338	193	32	increased	increase	VERB
dti-1338	193	33	sensitization	sensitization	NOUN
dti-1338	193	34	of	of	ADP
dti-1338	193	35	the	the	DET
dti-1338	193	36	cells	cell	NOUN
dti-1338	193	37	to	to	ADP
dti-1338	193	38	proliferation	proliferation	NOUN
dti-1338	193	39	inhibition	inhibition	NOUN
dti-1338	193	40	induced	induce	VERB
dti-1338	193	41	vpa	vpa	PROPN
dti-1338	193	42	.	.	PUNCT
dti-1338	194	1	based	base	VERB
dti-1338	194	2	on	on	ADP
dti-1338	194	3	the	the	DET
dti-1338	194	4	current	current	ADJ
dti-1338	194	5	results	result	NOUN
dti-1338	194	6	of	of	ADP
dti-1338	194	7	the	the	DET
dti-1338	194	8	effect	effect	NOUN
dti-1338	194	9	of	of	ADP
dti-1338	194	10	vpa	vpa	PROPN
dti-1338	194	11	on	on	ADP
dti-1338	194	12	mesenchymal	mesenchymal	NOUN
dti-1338	194	13	cell	cell	NOUN
dti-1338	194	14	proliferation	proliferation	NOUN
dti-1338	194	15	inhibition	inhibition	NOUN
dti-1338	194	16	,	,	PUNCT
dti-1338	194	17	we	we	PRON
dti-1338	194	18	assayed	assay	VERB
dti-1338	194	19	the	the	DET
dti-1338	194	20	effect	effect	NOUN
dti-1338	194	21	of	of	ADP
dti-1338	194	22	cell	cell	NOUN
dti-1338	194	23	differentiation	differentiation	NOUN
dti-1338	194	24	,	,	PUNCT
dti-1338	194	25	especially	especially	ADV
dti-1338	194	26	of	of	ADP
dti-1338	194	27	osteoblastic	osteoblastic	ADJ
dti-1338	194	28	cell	cell	NOUN
dti-1338	194	29	differentiation	differentiation	NOUN
dti-1338	194	30	,	,	PUNCT
dti-1338	194	31	in	in	ADP
dti-1338	194	32	the	the	DET
dti-1338	194	33	absence	absence	NOUN
dti-1338	194	34	or	or	CCONJ
dti-1338	194	35	presence	presence	NOUN
dti-1338	194	36	of	of	ADP
dti-1338	194	37	ecms	ecms	NOUN
dti-1338	194	38	.	.	PUNCT
dti-1338	195	1	our	our	PRON
dti-1338	195	2	results	result	NOUN
dti-1338	195	3	showed	show	VERB
dti-1338	195	4	that	that	SCONJ
dti-1338	195	5	vpa	vpa	PROPN
dti-1338	195	6	promoted	promote	VERB
dti-1338	195	7	osteoblastic	osteoblastic	ADJ
dti-1338	195	8	cell	cell	NOUN
dti-1338	195	9	differentiation	differentiation	NOUN
dti-1338	195	10	in	in	ADP
dti-1338	195	11	the	the	DET
dti-1338	195	12	presence	presence	NOUN
dti-1338	195	13	of	of	ADP
dti-1338	195	14	an	an	DET
dti-1338	195	15	extracellular	extracellular	ADJ
dti-1338	195	16	matrix	matrix	NOUN
dti-1338	195	17	,	,	PUNCT
dti-1338	195	18	the	the	DET
dti-1338	195	19	collagen	collagen	NOUN
dti-1338	195	20	-	-	PUNCT
dti-1338	195	21	coated	coated	ADJ
dti-1338	195	22	plate	plate	NOUN
dti-1338	195	23	.	.	PUNCT
dti-1338	196	1	this	this	DET
dti-1338	196	2	result	result	NOUN
dti-1338	196	3	indicates	indicate	VERB
dti-1338	196	4	that	that	SCONJ
dti-1338	196	5	the	the	DET
dti-1338	196	6	inhibitory	inhibitory	ADJ
dti-1338	196	7	effect	effect	NOUN
dti-1338	196	8	of	of	ADP
dti-1338	196	9	vpa	vpa	PROPN
dti-1338	196	10	on	on	ADP
dti-1338	196	11	cell	cell	NOUN
dti-1338	196	12	proliferation	proliferation	NOUN
dti-1338	196	13	on	on	ADP
dti-1338	196	14	the	the	DET
dti-1338	196	15	collagen	collagen	NOUN
dti-1338	196	16	-	-	PUNCT
dti-1338	196	17	coated	coated	ADJ
dti-1338	196	18	plate	plate	NOUN
dti-1338	196	19	at	at	ADP
dti-1338	196	20	lower	low	ADJ
dti-1338	196	21	concentrations	concentration	NOUN
dti-1338	196	22	compared	compare	VERB
dti-1338	196	23	with	with	ADP
dti-1338	196	24	that	that	PRON
dti-1338	196	25	on	on	ADP
dti-1338	196	26	the	the	DET
dti-1338	196	27	noncoated	noncoate	VERB
dti-1338	196	28	plastic	plastic	NOUN
dti-1338	196	29	plate	plate	NOUN
dti-1338	196	30	would	would	AUX
dti-1338	196	31	be	be	AUX
dti-1338	196	32	dependent	dependent	ADJ
dti-1338	196	33	on	on	ADP
dti-1338	196	34	the	the	DET
dti-1338	196	35	effect	effect	NOUN
dti-1338	196	36	of	of	ADP
dti-1338	196	37	vpa	vpa	PROPN
dti-1338	196	38	on	on	ADP
dti-1338	196	39	osteoblastic	osteoblastic	ADJ
dti-1338	196	40	cell	cell	NOUN
dti-1338	196	41	differentiation	differentiation	NOUN
dti-1338	196	42	from	from	ADP
dti-1338	196	43	mesenchymal	mesenchymal	ADJ
dti-1338	196	44	cells	cell	NOUN
dti-1338	196	45	to	to	PART
dti-1338	196	46	mature	mature	VERB
dti-1338	196	47	osteoblasts	osteoblast	NOUN
dti-1338	196	48	in	in	ADP
dti-1338	196	49	cooperation	cooperation	NOUN
dti-1338	196	50	with	with	ADP
dti-1338	196	51	collagen	collagen	NOUN
dti-1338	196	52	,	,	PUNCT
dti-1338	196	53	which	which	PRON
dti-1338	196	54	is	be	AUX
dti-1338	196	55	well	well	ADV
dti-1338	196	56	known	know	VERB
dti-1338	196	57	as	as	ADP
dti-1338	196	58	a	a	DET
dti-1338	196	59	promoter	promoter	NOUN
dti-1338	196	60	of	of	ADP
dti-1338	196	61	osteoblastic	osteoblastic	ADJ
dti-1338	196	62	cell	cell	NOUN
dti-1338	196	63	differentiation.20	differentiation.20	NOUN
dti-1338	196	64	because	because	SCONJ
dti-1338	196	65	it	it	PRON
dti-1338	196	66	has	have	AUX
dti-1338	196	67	been	be	AUX
dti-1338	196	68	reported	report	VERB
dti-1338	196	69	that	that	SCONJ
dti-1338	196	70	vpa	vpa	PROPN
dti-1338	196	71	promoted	promote	VERB
dti-1338	196	72	cell	cell	NOUN
dti-1338	196	73	differentiation	differentiation	NOUN
dti-1338	196	74	from	from	ADP
dti-1338	196	75	preosteoblast	preosteoblast	NOUN
dti-1338	196	76	to	to	PART
dti-1338	196	77	osteoblast	osteoblast	VERB
dti-1338	196	78	,	,	PUNCT
dti-1338	196	79	which	which	PRON
dti-1338	196	80	indicated	indicate	VERB
dti-1338	196	81	the	the	DET
dti-1338	196	82	effect	effect	NOUN
dti-1338	196	83	of	of	ADP
dti-1338	196	84	vpa	vpa	PROPN
dti-1338	196	85	on	on	ADP
dti-1338	196	86	cell	cell	NOUN
dti-1338	196	87	differentiation	differentiation	NOUN
dti-1338	196	88	in	in	ADP
dti-1338	196	89	committed	committed	ADJ
dti-1338	196	90	cells	cell	NOUN
dti-1338	196	91	such	such	ADJ
dti-1338	196	92	as	as	ADP
dti-1338	196	93	from	from	ADP
dti-1338	196	94	osteoblast	osteoblast	NOUN
dti-1338	196	95	to	to	PART
dti-1338	196	96	mature	mature	VERB
dti-1338	196	97	osteoblast,5	osteoblast,5	ADP
dti-1338	196	98	our	our	PRON
dti-1338	196	99	results	result	NOUN
dti-1338	196	100	suggested	suggest	VERB
dti-1338	196	101	that	that	SCONJ
dti-1338	196	102	vpa	vpa	PROPN
dti-1338	196	103	could	could	AUX
dti-1338	196	104	promote	promote	VERB
dti-1338	196	105	sequential	sequential	ADJ
dti-1338	196	106	cell	cell	NOUN
dti-1338	196	107	differentiation	differentiation	NOUN
dti-1338	196	108	from	from	ADP
dti-1338	196	109	uncommitted	uncommitted	ADJ
dti-1338	196	110	mesenchymal	mesenchymal	NOUN
dti-1338	196	111	cells	cell	NOUN
dti-1338	196	112	to	to	PART
dti-1338	196	113	mature	mature	VERB
dti-1338	196	114	osteoblasts	osteoblast	NOUN
dti-1338	196	115	in	in	ADP
dti-1338	196	116	the	the	DET
dti-1338	196	117	presence	presence	NOUN
dti-1338	196	118	of	of	ADP
dti-1338	196	119	ecms	ecms	NOUN
dti-1338	196	120	.	.	PUNCT
dti-1338	197	1	interestingly	interestingly	ADV
dti-1338	197	2	,	,	PUNCT
dti-1338	197	3	vpa	vpa	PROPN
dti-1338	197	4	increased	increase	VERB
dti-1338	197	5	the	the	DET
dti-1338	197	6	gene	gene	NOUN
dti-1338	197	7	expression	expression	NOUN
dti-1338	197	8	level	level	NOUN
dti-1338	197	9	of	of	ADP
dti-1338	197	10	osteoblastic	osteoblastic	ADJ
dti-1338	197	11	marker	marker	NOUN
dti-1338	197	12	genes	gene	NOUN
dti-1338	197	13	even	even	ADV
dti-1338	197	14	on	on	ADP
dti-1338	197	15	the	the	DET
dti-1338	197	16	non	non	ADJ
dti-1338	197	17	-	-	ADJ
dti-1338	197	18	coated	coated	ADJ
dti-1338	197	19	plastic	plastic	NOUN
dti-1338	197	20	plate	plate	NOUN
dti-1338	197	21	,	,	PUNCT
dti-1338	197	22	in	in	ADP
dti-1338	197	23	which	which	PRON
dti-1338	197	24	vpa	vpa	PROPN
dti-1338	197	25	had	have	VERB
dti-1338	197	26	no	no	DET
dti-1338	197	27	inhibitory	inhibitory	ADJ
dti-1338	197	28	effect	effect	NOUN
dti-1338	197	29	on	on	ADP
dti-1338	197	30	cell	cell	NOUN
dti-1338	197	31	proliferation	proliferation	NOUN
dti-1338	197	32	in	in	ADP
dti-1338	197	33	low	low	ADJ
dti-1338	197	34	concentrations	concentration	NOUN
dti-1338	197	35	.	.	PUNCT
dti-1338	198	1	since	since	SCONJ
dti-1338	198	2	we	we	PRON
dti-1338	198	3	added	add	VERB
dti-1338	198	4	minimum	minimum	ADJ
dti-1338	198	5	supplements	supplement	NOUN
dti-1338	198	6	for	for	ADP
dti-1338	198	7	osteoblastic	osteoblastic	ADJ
dti-1338	198	8	cell	cell	NOUN
dti-1338	198	9	differentiation	differentiation	NOUN
dti-1338	198	10	including	include	VERB
dti-1338	198	11	ascorbic	ascorbic	NOUN
dti-1338	198	12	acid	acid	NOUN
dti-1338	198	13	and	and	CCONJ
dti-1338	198	14	dexamethasone	dexamethasone	NOUN
dti-1338	198	15	,	,	PUNCT
dti-1338	198	16	which	which	PRON
dti-1338	198	17	are	be	AUX
dti-1338	198	18	widely	widely	ADV
dti-1338	198	19	used	use	VERB
dti-1338	198	20	for	for	ADP
dti-1338	198	21	basal	basal	ADJ
dti-1338	198	22	induction	induction	NOUN
dti-1338	198	23	of	of	ADP
dti-1338	198	24	osteoblastic	osteoblastic	ADJ
dti-1338	198	25	cell	cell	NOUN
dti-1338	198	26	differentiation	differentiation	NOUN
dti-1338	198	27	of	of	ADP
dti-1338	198	28	various	various	ADJ
dti-1338	198	29	mesenchymal	mesenchymal	ADJ
dti-1338	198	30	cells	cell	NOUN
dti-1338	198	31	including	include	VERB
dti-1338	198	32	c3h10t1/2,21–23	c3h10t1/2,21–23	PROPN
dti-1338	198	33	vpa	vpa	PROPN
dti-1338	198	34	may	may	AUX
dti-1338	198	35	enhance	enhance	VERB
dti-1338	198	36	osteoblast	osteoblast	ADJ
dti-1338	198	37	cell	cell	NOUN
dti-1338	198	38	fate	fate	NOUN
dti-1338	198	39	determination	determination	NOUN
dti-1338	198	40	and	and	CCONJ
dti-1338	198	41	promote	promote	VERB
dti-1338	198	42	cell	cell	NOUN
dti-1338	198	43	differentiation	differentiation	NOUN
dti-1338	198	44	in	in	ADP
dti-1338	198	45	the	the	DET
dti-1338	198	46	presence	presence	NOUN
dti-1338	198	47	of	of	ADP
dti-1338	198	48	ecms	ecms	NOUN
dti-1338	198	49	.	.	PUNCT
dti-1338	199	1	in	in	ADP
dti-1338	199	2	summary	summary	NOUN
dti-1338	199	3	,	,	PUNCT
dti-1338	199	4	this	this	DET
dti-1338	199	5	study	study	NOUN
dti-1338	199	6	reported	report	VERB
dti-1338	199	7	on	on	ADP
dti-1338	199	8	the	the	DET
dti-1338	199	9	relationship	relationship	NOUN
dti-1338	199	10	of	of	ADP
dti-1338	199	11	vpa	vpa	PROPN
dti-1338	199	12	and	and	CCONJ
dti-1338	199	13	ecms	ecms	PROPN
dti-1338	199	14	in	in	ADP
dti-1338	199	15	mesenchymal	mesenchymal	ADJ
dti-1338	199	16	cell	cell	NOUN
dti-1338	199	17	proliferation	proliferation	NOUN
dti-1338	199	18	and	and	CCONJ
dti-1338	199	19	cell	cell	NOUN
dti-1338	199	20	differentiation	differentiation	NOUN
dti-1338	199	21	.	.	PUNCT
dti-1338	200	1	additionally	additionally	ADV
dti-1338	200	2	,	,	PUNCT
dti-1338	200	3	this	this	DET
dti-1338	200	4	study	study	NOUN
dti-1338	200	5	could	could	AUX
dti-1338	200	6	reflect	reflect	VERB
dti-1338	200	7	the	the	DET
dti-1338	200	8	effects	effect	NOUN
dti-1338	200	9	of	of	ADP
dti-1338	200	10	vpa	vpa	PROPN
dti-1338	200	11	in	in	ADP
dti-1338	200	12	in	in	ADP
dti-1338	200	13	vivo	vivo	ADJ
dti-1338	200	14	conditions	condition	NOUN
dti-1338	200	15	,	,	PUNCT
dti-1338	200	16	but	but	CCONJ
dti-1338	200	17	further	further	ADJ
dti-1338	200	18	research	research	NOUN
dti-1338	200	19	would	would	AUX
dti-1338	200	20	be	be	AUX
dti-1338	200	21	necessary	necessary	ADJ
dti-1338	200	22	to	to	PART
dti-1338	200	23	clarify	clarify	VERB
dti-1338	200	24	the	the	DET
dti-1338	200	25	mechanism	mechanism	NOUN
dti-1338	200	26	of	of	ADP
dti-1338	200	27	cell	cell	NOUN
dti-1338	200	28	proliferation	proliferation	NOUN
dti-1338	200	29	in	in	ADP
dti-1338	200	30	the	the	DET
dti-1338	200	31	co	co	NOUN
dti-1338	200	32	-	-	NOUN
dti-1338	200	33	presence	presence	NOUN
dti-1338	200	34	of	of	ADP
dti-1338	200	35	vpa	vpa	PROPN
dti-1338	200	36	and	and	CCONJ
dti-1338	200	37	other	other	ADJ
dti-1338	200	38	ecms	ecms	NOUN
dti-1338	200	39	to	to	PART
dti-1338	200	40	provide	provide	VERB
dti-1338	200	41	further	further	ADJ
dti-1338	200	42	insight	insight	NOUN
dti-1338	200	43	into	into	ADP
dti-1338	200	44	the	the	DET
dti-1338	200	45	effect	effect	NOUN
dti-1338	200	46	of	of	ADP
dti-1338	200	47	vpa	vpa	PROPN
dti-1338	200	48	in	in	ADP
dti-1338	200	49	mesenchymal	mesenchymal	ADJ
dti-1338	200	50	tissue	tissue	NOUN
dti-1338	200	51	development	development	NOUN
dti-1338	200	52	.	.	PUNCT
dti-1338	201	1	acknowledgements	acknowledgement	NOUN
dti-1338	201	2	we	we	PRON
dti-1338	201	3	are	be	AUX
dti-1338	201	4	grateful	grateful	ADJ
dti-1338	201	5	to	to	ADP
dti-1338	201	6	dr	dr	PROPN
dti-1338	201	7	.	.	PROPN
dti-1338	201	8	yasuyuki	yasuyuki	PROPN
dti-1338	201	9	sasano	sasano	PROPN
dti-1338	201	10	,	,	PUNCT
dti-1338	201	11	dr	dr	PROPN
dti-1338	201	12	.	.	PROPN
dti-1338	201	13	kojiro	kojiro	PROPN
dti-1338	201	14	tanaka	tanaka	PROPN
dti-1338	201	15	and	and	CCONJ
dti-1338	201	16	dr	dr	PROPN
dti-1338	201	17	.	.	PROPN
dti-1338	201	18	yasuko	yasuko	PROPN
dti-1338	201	19	kimura	kimura	NOUN
dti-1338	201	20	of	of	ADP
dti-1338	201	21	the	the	DET
dti-1338	201	22	graduate	graduate	ADJ
dti-1338	201	23	school	school	NOUN
dti-1338	201	24	of	of	ADP
dti-1338	201	25	dentistry	dentistry	NOUN
dti-1338	201	26	at	at	ADP
dti-1338	201	27	tohoku	tohoku	PROPN
dti-1338	201	28	university	university	PROPN
dti-1338	201	29	for	for	ADP
dti-1338	201	30	their	their	PRON
dti-1338	201	31	valuable	valuable	ADJ
dti-1338	201	32	insight	insight	NOUN
dti-1338	201	33	and	and	CCONJ
dti-1338	201	34	assistance	assistance	NOUN
dti-1338	201	35	.	.	PUNCT
dti-1338	202	1	disclosure	disclosure	NOUN
dti-1338	202	2	this	this	DET
dti-1338	202	3	manuscript	manuscript	NOUN
dti-1338	202	4	has	have	AUX
dti-1338	202	5	been	be	AUX
dti-1338	202	6	read	read	VERB
dti-1338	202	7	and	and	CCONJ
dti-1338	202	8	approved	approve	VERB
dti-1338	202	9	by	by	ADP
dti-1338	202	10	all	all	DET
dti-1338	202	11	authors	author	NOUN
dti-1338	202	12	.	.	PUNCT
dti-1338	203	1	this	this	DET
dti-1338	203	2	paper	paper	NOUN
dti-1338	203	3	is	be	AUX
dti-1338	203	4	unique	unique	ADJ
dti-1338	203	5	and	and	CCONJ
dti-1338	203	6	is	be	AUX
dti-1338	203	7	not	not	PART
dti-1338	203	8	under	under	ADP
dti-1338	203	9	consideration	consideration	NOUN
dti-1338	203	10	by	by	ADP
dti-1338	203	11	any	any	DET
dti-1338	203	12	other	other	ADJ
dti-1338	203	13	publication	publication	NOUN
dti-1338	203	14	and	and	CCONJ
dti-1338	203	15	has	have	AUX
dti-1338	203	16	not	not	PART
dti-1338	203	17	been	be	AUX
dti-1338	203	18	published	publish	VERB
dti-1338	203	19	elsewhere	elsewhere	ADV
dti-1338	203	20	.	.	PUNCT
dti-1338	204	1	the	the	DET
dti-1338	204	2	authors	author	NOUN
dti-1338	204	3	and	and	CCONJ
dti-1338	204	4	peer	peer	NOUN
dti-1338	204	5	reviewers	reviewer	NOUN
dti-1338	204	6	of	of	ADP
dti-1338	204	7	this	this	DET
dti-1338	204	8	paper	paper	NOUN
dti-1338	204	9	report	report	NOUN
dti-1338	204	10	no	no	DET
dti-1338	204	11	conflicts	conflict	NOUN
dti-1338	204	12	of	of	ADP
dti-1338	204	13	interest	interest	NOUN
dti-1338	204	14	.	.	PUNCT
dti-1338	205	1	the	the	DET
dti-1338	205	2	authors	author	NOUN
dti-1338	205	3	confirm	confirm	VERB
dti-1338	205	4	that	that	SCONJ
dti-1338	205	5	they	they	PRON
dti-1338	205	6	have	have	VERB
dti-1338	205	7	permission	permission	NOUN
dti-1338	205	8	to	to	PART
dti-1338	205	9	reproduce	reproduce	VERB
dti-1338	205	10	any	any	DET
dti-1338	205	11	copyrighted	copyright	VERB
dti-1338	205	12	material	material	NOUN
dti-1338	205	13	.	.	PUNCT
dti-1338	206	1	references	reference	NOUN
dti-1338	206	2	1	1	NUM
dti-1338	206	3	.	.	PUNCT
dti-1338	206	4	sheth	sheth	PROPN
dti-1338	206	5	rd	rd	PROPN
dti-1338	206	6	,	,	PUNCT
dti-1338	206	7	wesolowski	wesolowski	PROPN
dti-1338	206	8	ca	ca	PROPN
dti-1338	206	9	,	,	PUNCT
dti-1338	206	10	jacob	jacob	PROPN
dti-1338	206	11	jc	jc	PROPN
dti-1338	206	12	,	,	PUNCT
dti-1338	206	13	et	et	PROPN
dti-1338	206	14	al	al	PROPN
dti-1338	206	15	.	.	PROPN
dti-1338	206	16	effect	effect	NOUN
dti-1338	206	17	of	of	ADP
dti-1338	206	18	carbamazepine	carbamazepine	NOUN
dti-1338	206	19	and	and	CCONJ
dti-1338	206	20	valproate	valproate	VERB
dti-1338	206	21	on	on	ADP
dti-1338	206	22	bone	bone	NOUN
dti-1338	206	23	mineral	mineral	NOUN
dti-1338	206	24	density	density	NOUN
dti-1338	206	25	.	.	PUNCT
dti-1338	207	1	j	j	PROPN
dti-1338	207	2	pediatr	pediatr	PROPN
dti-1338	207	3	.	.	PUNCT
dti-1338	208	1	1995;127(2):256–62	1995;127(2):256–62	NUM
dti-1338	208	2	.	.	NOUN
dti-1338	209	1	2	2	NUM
dti-1338	209	2	.	.	X
dti-1338	209	3	massa	massa	PROPN
dti-1338	209	4	v	v	PROPN
dti-1338	209	5	,	,	PUNCT
dti-1338	209	6	cabrera	cabrera	PROPN
dti-1338	209	7	rm	rm	PROPN
dti-1338	209	8	,	,	PUNCT
dti-1338	209	9	megegola	megegola	X
dti-1338	209	10	e	e	PROPN
dti-1338	209	11	,	,	PUNCT
dti-1338	209	12	giavini	giavini	NOUN
dti-1338	209	13	e	e	NOUN
dti-1338	209	14	,	,	PUNCT
dti-1338	209	15	finnell	finnell	PROPN
dti-1338	209	16	rh	rh	PROPN
dti-1338	209	17	.	.	PUNCT
dti-1338	210	1	valproic	valproic	ADJ
dti-1338	210	2	acidinduced	acidinduce	VERB
dti-1338	210	3	skeletal	skeletal	ADJ
dti-1338	210	4	malformations	malformation	NOUN
dti-1338	210	5	:	:	PUNCT
dti-1338	210	6	associated	associated	ADJ
dti-1338	210	7	gene	gene	NOUN
dti-1338	210	8	expression	expression	NOUN
dti-1338	210	9	cascades	cascade	NOUN
dti-1338	210	10	.	.	PUNCT
dti-1338	211	1	pharmacogenet	pharmacogenet	NOUN
dti-1338	211	2	genomics	genomic	NOUN
dti-1338	211	3	.	.	PUNCT
dti-1338	212	1	2005;15(11):787–800	2005;15(11):787–800	NUM
dti-1338	212	2	.	.	PUNCT
dti-1338	213	1	3	3	X
dti-1338	213	2	.	.	X
dti-1338	213	3	ardinger	ardinger	PROPN
dti-1338	213	4	hh	hh	PROPN
dti-1338	213	5	,	,	PUNCT
dti-1338	213	6	atkin	atkin	PROPN
dti-1338	213	7	jf	jf	PROPN
dti-1338	213	8	,	,	PUNCT
dti-1338	213	9	blackston	blackston	PROPN
dti-1338	213	10	rd	rd	PROPN
dti-1338	213	11	,	,	PUNCT
dti-1338	213	12	et	et	PROPN
dti-1338	213	13	al	al	PROPN
dti-1338	213	14	.	.	PUNCT
dti-1338	213	15	verification	verification	NOUN
dti-1338	213	16	of	of	ADP
dti-1338	213	17	the	the	DET
dti-1338	213	18	fetal	fetal	ADJ
dti-1338	213	19	valproate	valproate	ADJ
dti-1338	213	20	syndrome	syndrome	NOUN
dti-1338	213	21	phenotype	phenotype	NOUN
dti-1338	213	22	.	.	PUNCT
dti-1338	214	1	am	be	AUX
dti-1338	214	2	j	j	PROPN
dti-1338	214	3	med	med	PROPN
dti-1338	214	4	genet	genet	NOUN
dti-1338	214	5	.	.	PUNCT
dti-1338	215	1	1988;29(1):171–85	1988;29(1):171–85	NUM
dti-1338	215	2	.	.	NOUN
dti-1338	215	3	4	4	NUM
dti-1338	215	4	.	.	X
dti-1338	215	5	schroeder	schroeder	PROPN
dti-1338	215	6	tm	tm	PROPN
dti-1338	215	7	,	,	PUNCT
dti-1338	215	8	westendorf	westendorf	VERB
dti-1338	215	9	jj	jj	PROPN
dti-1338	215	10	.	.	PROPN
dti-1338	215	11	histone	histone	PROPN
dti-1338	215	12	deacetylase	deacetylase	VERB
dti-1338	215	13	inhibitors	inhibitor	NOUN
dti-1338	215	14	promote	promote	VERB
dti-1338	215	15	osteoblast	osteoblast	ADJ
dti-1338	215	16	maturation	maturation	NOUN
dti-1338	215	17	.	.	PUNCT
dti-1338	216	1	j	j	PROPN
dti-1338	216	2	bone	bone	NOUN
dti-1338	216	3	miner	miner	NOUN
dti-1338	216	4	res	re	NOUN
dti-1338	216	5	.	.	PUNCT
dti-1338	217	1	2005;20(12):2254–63	2005;20(12):2254–63	NUM
dti-1338	217	2	.	.	PUNCT
dti-1338	218	1	5	5	X
dti-1338	218	2	.	.	X
dti-1338	218	3	okada	okada	PROPN
dti-1338	218	4	a	a	PROPN
dti-1338	218	5	,	,	PUNCT
dti-1338	218	6	shiomi	shiomi	PROPN
dti-1338	218	7	t	t	PROPN
dti-1338	218	8	,	,	PUNCT
dti-1338	218	9	aoki	aoki	PROPN
dti-1338	218	10	y	y	PROPN
dti-1338	218	11	,	,	PUNCT
dti-1338	218	12	fujiwara	fujiwara	PROPN
dti-1338	218	13	m.	m.	PROPN
dti-1338	218	14	phenytoin	phenytoin	PROPN
dti-1338	218	15	stimulates	stimulate	VERB
dti-1338	218	16	chondrogenic	chondrogenic	ADJ
dti-1338	218	17	differentiation	differentiation	NOUN
dti-1338	218	18	in	in	ADP
dti-1338	218	19	mouse	mouse	NOUN
dti-1338	218	20	clonal	clonal	ADJ
dti-1338	218	21	chondrogenic	chondrogenic	ADJ
dti-1338	218	22	cells	cell	NOUN
dti-1338	218	23	,	,	PUNCT
dti-1338	218	24	atdc5	atdc5	PROPN
dti-1338	218	25	.	.	PUNCT
dti-1338	219	1	j	j	PROPN
dti-1338	219	2	toxicol	toxicol	PROPN
dti-1338	219	3	sci	sci	PROPN
dti-1338	219	4	.	.	PUNCT
dti-1338	220	1	2005;30(3):145–56	2005;30(3):145–56	NUM
dti-1338	220	2	.	.	PUNCT
dti-1338	221	1	6	6	NUM
dti-1338	221	2	.	.	X
dti-1338	221	3	zehentner	zehentner	NOUN
dti-1338	221	4	bk	bk	PROPN
dti-1338	221	5	,	,	PUNCT
dti-1338	221	6	leser	leser	PROPN
dti-1338	221	7	u	u	NOUN
dti-1338	221	8	,	,	PUNCT
dti-1338	221	9	burtscher	burtscher	PROPN
dti-1338	221	10	h.	h.	PROPN
dti-1338	221	11	bmp-2	bmp-2	PUNCT
dti-1338	221	12	and	and	CCONJ
dti-1338	221	13	sonic	sonic	ADJ
dti-1338	221	14	hedgehog	hedgehog	NOUN
dti-1338	221	15	have	have	VERB
dti-1338	221	16	contrary	contrary	ADJ
dti-1338	221	17	effects	effect	NOUN
dti-1338	221	18	on	on	ADP
dti-1338	221	19	adipocyte	adipocyte	NOUN
dti-1338	221	20	-	-	PUNCT
dti-1338	221	21	like	like	ADJ
dti-1338	221	22	differentiation	differentiation	NOUN
dti-1338	221	23	of	of	ADP
dti-1338	221	24	c3h10t1/2	c3h10t1/2	PROPN
dti-1338	221	25	cells	cell	NOUN
dti-1338	221	26	.	.	PUNCT
dti-1338	222	1	dna	dna	PROPN
dti-1338	222	2	cell	cell	NOUN
dti-1338	222	3	biol	biol	NOUN
dti-1338	222	4	.	.	PUNCT
dti-1338	223	1	2000;19(5):275–81	2000;19(5):275–81	NUM
dti-1338	223	2	.	.	NOUN
dti-1338	223	3	7	7	X
dti-1338	223	4	.	.	NUM
dti-1338	223	5	ahrens	ahrens	PROPN
dti-1338	223	6	m	m	PROPN
dti-1338	223	7	,	,	PUNCT
dti-1338	223	8	ankenbauer	ankenbauer	PROPN
dti-1338	223	9	t	t	PROPN
dti-1338	223	10	,	,	PUNCT
dti-1338	223	11	schroder	schroder	PROPN
dti-1338	223	12	d	d	PROPN
dti-1338	223	13	,	,	PUNCT
dti-1338	223	14	hollnagel	hollnagel	NOUN
dti-1338	223	15	a	a	PRON
dti-1338	223	16	,	,	PUNCT
dti-1338	223	17	mayer	mayer	PROPN
dti-1338	223	18	h	h	PROPN
dti-1338	223	19	,	,	PUNCT
dti-1338	223	20	gross	gross	ADJ
dti-1338	223	21	g.	g.	NOUN
dti-1338	223	22	expression	expression	NOUN
dti-1338	223	23	of	of	ADP
dti-1338	223	24	human	human	ADJ
dti-1338	223	25	bone	bone	NOUN
dti-1338	223	26	morphogenetic	morphogenetic	ADJ
dti-1338	223	27	proteins-2	proteins-2	PROPN
dti-1338	223	28	or	or	CCONJ
dti-1338	223	29	-4	-4	INTJ
dti-1338	223	30	in	in	ADP
dti-1338	223	31	murine	murine	ADJ
dti-1338	223	32	mesenchymal	mesenchymal	ADJ
dti-1338	223	33	progenitor	progenitor	NOUN
dti-1338	223	34	c3h10t1/2	c3h10t1/2	PROPN
dti-1338	223	35	cells	cell	NOUN
dti-1338	223	36	induces	induce	VERB
dti-1338	223	37	differentiation	differentiation	NOUN
dti-1338	223	38	into	into	ADP
dti-1338	223	39	distinct	distinct	ADJ
dti-1338	223	40	mesenchymal	mesenchymal	ADJ
dti-1338	223	41	cell	cell	NOUN
dti-1338	223	42	lineages	lineage	NOUN
dti-1338	223	43	.	.	PUNCT
dti-1338	224	1	dna	dna	PROPN
dti-1338	224	2	cell	cell	NOUN
dti-1338	224	3	biol	biol	PROPN
dti-1338	224	4	.	.	PUNCT
dti-1338	225	1	1993;12(10):871–80	1993;12(10):871–80	NUM
dti-1338	225	2	.	.	X
dti-1338	226	1	8	8	NUM
dti-1338	226	2	.	.	X
dti-1338	226	3	katagiri	katagiri	PROPN
dti-1338	226	4	t	t	PROPN
dti-1338	226	5	,	,	PUNCT
dti-1338	226	6	yamaguchi	yamaguchi	PROPN
dti-1338	226	7	a	a	PROPN
dti-1338	226	8	,	,	PUNCT
dti-1338	226	9	ikeda	ikeda	PROPN
dti-1338	226	10	t	t	PROPN
dti-1338	226	11	,	,	PUNCT
dti-1338	226	12	yoshiki	yoshiki	PROPN
dti-1338	226	13	s	s	PROPN
dti-1338	226	14	,	,	PUNCT
dti-1338	226	15	et	et	PROPN
dti-1338	226	16	al	al	PROPN
dti-1338	226	17	.	.	PUNCT
dti-1338	227	1	the	the	DET
dti-1338	227	2	non	non	ADJ
dti-1338	227	3	-	-	ADJ
dti-1338	227	4	osteogenic	osteogenic	ADJ
dti-1338	227	5	mouse	mouse	NOUN
dti-1338	227	6	pluripotent	pluripotent	ADJ
dti-1338	227	7	cell	cell	NOUN
dti-1338	227	8	line	line	NOUN
dti-1338	227	9	,	,	PUNCT
dti-1338	227	10	c3h10t1/2	c3h10t1/2	PROPN
dti-1338	227	11	is	be	AUX
dti-1338	227	12	induced	induce	VERB
dti-1338	227	13	to	to	PART
dti-1338	227	14	differentiate	differentiate	VERB
dti-1338	227	15	into	into	ADP
dti-1338	227	16	osteoblastic	osteoblastic	ADJ
dti-1338	227	17	cells	cell	NOUN
dti-1338	227	18	by	by	ADP
dti-1338	227	19	recombinant	recombinant	ADJ
dti-1338	227	20	human	human	ADJ
dti-1338	227	21	bone	bone	NOUN
dti-1338	227	22	morphogenetic	morphogenetic	ADJ
dti-1338	227	23	protein-2	protein-2	PROPN
dti-1338	227	24	.	.	PUNCT
dti-1338	227	25	biochem	biochem	PROPN
dti-1338	227	26	biophys	biophys	PROPN
dti-1338	227	27	res	re	NOUN
dti-1338	227	28	commun	commun	PROPN
dti-1338	227	29	.	.	PUNCT
dti-1338	228	1	1990;172(1):295–9	1990;172(1):295–9	PROPN
dti-1338	228	2	.	.	PUNCT
dti-1338	229	1	9	9	NUM
dti-1338	229	2	.	.	PUNCT
dti-1338	229	3	garcía	garcía	PROPN
dti-1338	229	4	aj	aj	PROPN
dti-1338	229	5	,	,	PUNCT
dti-1338	229	6	reyes	reyes	PROPN
dti-1338	229	7	cd	cd	PROPN
dti-1338	229	8	.	.	PUNCT
dti-1338	229	9	bio	bio	PROPN
dti-1338	229	10	-	-	ADJ
dti-1338	229	11	adhesive	adhesive	ADJ
dti-1338	229	12	surfaces	surface	NOUN
dti-1338	229	13	to	to	PART
dti-1338	229	14	promote	promote	VERB
dti-1338	229	15	osteoblast	osteoblast	ADJ
dti-1338	229	16	differentiation	differentiation	NOUN
dti-1338	229	17	and	and	CCONJ
dti-1338	229	18	bone	bone	NOUN
dti-1338	229	19	formation	formation	NOUN
dti-1338	229	20	.	.	PUNCT
dti-1338	230	1	j	j	PROPN
dti-1338	230	2	dent	dent	NOUN
dti-1338	230	3	res	re	NOUN
dti-1338	230	4	.	.	PUNCT
dti-1338	231	1	2005;84(5):407–13	2005;84(5):407–13	NUM
dti-1338	231	2	.	.	NOUN
dti-1338	231	3	10	10	NUM
dti-1338	231	4	.	.	PUNCT
dti-1338	231	5	andrianarivo	andrianarivo	PROPN
dti-1338	231	6	ag	ag	PROPN
dti-1338	231	7	,	,	PUNCT
dti-1338	231	8	robinson	robinson	PROPN
dti-1338	231	9	ja	ja	PROPN
dti-1338	231	10	,	,	PUNCT
dti-1338	231	11	mann	mann	PROPN
dti-1338	231	12	kg	kg	PROPN
dti-1338	231	13	,	,	PUNCT
dti-1338	231	14	tracy	tracy	PROPN
dti-1338	231	15	rp	rp	PROPN
dti-1338	231	16	.	.	PUNCT
dti-1338	232	1	growth	growth	NOUN
dti-1338	232	2	on	on	ADP
dti-1338	232	3	type	type	NOUN
dti-1338	232	4	i	i	PRON
dti-1338	232	5	collagen	collagen	NOUN
dti-1338	232	6	promotes	promote	VERB
dti-1338	232	7	expression	expression	NOUN
dti-1338	232	8	of	of	ADP
dti-1338	232	9	the	the	DET
dti-1338	232	10	osteoblastic	osteoblastic	ADJ
dti-1338	232	11	phenotype	phenotype	NOUN
dti-1338	232	12	in	in	ADP
dti-1338	232	13	human	human	ADJ
dti-1338	232	14	osteosarcoma	osteosarcoma	ADJ
dti-1338	232	15	mg-63	mg-63	NOUN
dti-1338	232	16	cells	cell	NOUN
dti-1338	232	17	.	.	PUNCT
dti-1338	233	1	j	j	PROPN
dti-1338	233	2	cell	cell	NOUN
dti-1338	233	3	physiol	physiol	PROPN
dti-1338	233	4	.	.	PUNCT
dti-1338	234	1	1992;153(2):256–65	1992;153(2):256–65	X
dti-1338	234	2	.	.	PUNCT
dti-1338	235	1	11	11	NUM
dti-1338	235	2	.	.	PUNCT
dti-1338	236	1	lynch	lynch	PROPN
dti-1338	236	2	mp	mp	PROPN
dti-1338	236	3	,	,	PUNCT
dti-1338	236	4	stein	stein	PROPN
dti-1338	236	5	jl	jl	PROPN
dti-1338	236	6	,	,	PUNCT
dti-1338	236	7	stein	stein	PROPN
dti-1338	236	8	gs	gs	PROPN
dti-1338	236	9	,	,	PUNCT
dti-1338	236	10	lian	lian	PROPN
dti-1338	236	11	jb	jb	PROPN
dti-1338	236	12	.	.	PUNCT
dti-1338	237	1	the	the	DET
dti-1338	237	2	influence	influence	NOUN
dti-1338	237	3	of	of	ADP
dti-1338	237	4	type	type	NOUN
dti-1338	237	5	i	i	PRON
dti-1338	237	6	collagen	collagen	VERB
dti-1338	237	7	on	on	ADP
dti-1338	237	8	the	the	DET
dti-1338	237	9	development	development	NOUN
dti-1338	237	10	and	and	CCONJ
dti-1338	237	11	maintenance	maintenance	NOUN
dti-1338	237	12	of	of	ADP
dti-1338	237	13	the	the	DET
dti-1338	237	14	osteoblast	osteoblast	ADJ
dti-1338	237	15	phenotype	phenotype	NOUN
dti-1338	237	16	in	in	ADP
dti-1338	237	17	primary	primary	ADJ
dti-1338	237	18	and	and	CCONJ
dti-1338	237	19	passaged	passaged	ADJ
dti-1338	237	20	rat	rat	NOUN
dti-1338	237	21	calvarial	calvarial	ADJ
dti-1338	237	22	osteoblasts	osteoblast	NOUN
dti-1338	237	23	:	:	PUNCT
dti-1338	237	24	modification	modification	NOUN
dti-1338	237	25	of	of	ADP
dti-1338	237	26	expression	expression	NOUN
dti-1338	237	27	genes	gene	NOUN
dti-1338	237	28	supporting	support	VERB
dti-1338	237	29	cell	cell	NOUN
dti-1338	237	30	growth	growth	NOUN
dti-1338	237	31	,	,	PUNCT
dti-1338	237	32	adhesion	adhesion	NOUN
dti-1338	237	33	,	,	PUNCT
dti-1338	237	34	and	and	CCONJ
dti-1338	237	35	exracellular	exracellular	ADJ
dti-1338	237	36	matrix	matrix	NOUN
dti-1338	237	37	mineralization	mineralization	NOUN
dti-1338	237	38	.	.	PUNCT
dti-1338	238	1	exp	exp	NOUN
dti-1338	238	2	cell	cell	NOUN
dti-1338	238	3	res	re	NOUN
dti-1338	238	4	.	.	PUNCT
dti-1338	239	1	1995;216(1):35–45	1995;216(1):35–45	X
dti-1338	239	2	.	.	PUNCT
dti-1338	240	1	12	12	NUM
dti-1338	240	2	.	.	PUNCT
dti-1338	241	1	weiss	weiss	PROPN
dti-1338	241	2	re	re	PROPN
dti-1338	241	3	,	,	PUNCT
dti-1338	241	4	reddi	reddi	PROPN
dti-1338	241	5	ah	ah	INTJ
dti-1338	241	6	.	.	PUNCT
dti-1338	241	7	synthesis	synthesis	NOUN
dti-1338	241	8	and	and	CCONJ
dti-1338	241	9	localization	localization	NOUN
dti-1338	241	10	of	of	ADP
dti-1338	241	11	fibronectin	fibronectin	NOUN
dti-1338	241	12	during	during	ADP
dti-1338	241	13	collagenous	collagenous	ADJ
dti-1338	241	14	matrix	matrix	NOUN
dti-1338	241	15	-	-	PUNCT
dti-1338	241	16	mesenchymal	mesenchymal	NOUN
dti-1338	241	17	cell	cell	NOUN
dti-1338	241	18	interaction	interaction	NOUN
dti-1338	241	19	and	and	CCONJ
dti-1338	241	20	differentiation	differentiation	NOUN
dti-1338	241	21	of	of	ADP
dti-1338	241	22	cartilage	cartilage	NOUN
dti-1338	241	23	and	and	CCONJ
dti-1338	241	24	bone	bone	NOUN
dti-1338	241	25	in	in	ADP
dti-1338	241	26	vivo	vivo	NOUN
dti-1338	241	27	.	.	PUNCT
dti-1338	242	1	proc	proc	PROPN
dti-1338	242	2	natl	natl	PROPN
dti-1338	242	3	acad	acad	PROPN
dti-1338	242	4	sci	sci	PROPN
dti-1338	242	5	u	u	PROPN
dti-1338	242	6	s	s	NOUN
dti-1338	242	7	a.	a.	NOUN
dti-1338	242	8	1980;77(4	1980;77(4	NUM
dti-1338	242	9	):	):	PUNCT
dti-1338	242	10	2074–8	2074–8	NUM
dti-1338	242	11	.	.	NOUN
dti-1338	242	12	13	13	NUM
dti-1338	242	13	.	.	PUNCT
dti-1338	243	1	yamada	yamada	PROPN
dti-1338	243	2	km	km	PROPN
dti-1338	243	3	,	,	PUNCT
dti-1338	243	4	olden	olden	PROPN
dti-1338	243	5	k.	k.	PROPN
dti-1338	243	6	fibronectins	fibronectins	PROPN
dti-1338	243	7	,	,	PUNCT
dti-1338	243	8	adhesive	adhesive	ADJ
dti-1338	243	9	glycoproteins	glycoprotein	NOUN
dti-1338	243	10	of	of	ADP
dti-1338	243	11	cell	cell	NOUN
dti-1338	243	12	surface	surface	NOUN
dti-1338	243	13	and	and	CCONJ
dti-1338	243	14	blood	blood	NOUN
dti-1338	243	15	.	.	PUNCT
dti-1338	244	1	nature	nature	NOUN
dti-1338	244	2	.	.	PUNCT
dti-1338	245	1	1978;275(5677):179–84	1978;275(5677):179–84	NOUN
dti-1338	245	2	.	.	PUNCT
dti-1338	246	1	14	14	NUM
dti-1338	246	2	.	.	PUNCT
dti-1338	247	1	hatakeyama	hatakeyama	PROPN
dti-1338	247	2	j	j	PROPN
dti-1338	247	3	,	,	PUNCT
dti-1338	247	4	hatakeyama	hatakeyama	PROPN
dti-1338	247	5	y	y	PROPN
dti-1338	247	6	,	,	PUNCT
dti-1338	247	7	takahashi	takahashi	PROPN
dti-1338	247	8	i	i	PROPN
dti-1338	247	9	,	,	PUNCT
dti-1338	247	10	suzuki	suzuki	PROPN
dti-1338	247	11	o	o	PROPN
dti-1338	247	12	,	,	PUNCT
dti-1338	247	13	sasano	sasano	PROPN
dti-1338	247	14	y.	y.	NOUN
dti-1338	247	15	proliferation	proliferation	NOUN
dti-1338	247	16	and	and	CCONJ
dti-1338	247	17	adhesion	adhesion	NOUN
dti-1338	247	18	of	of	ADP
dti-1338	247	19	periodontal	periodontal	ADJ
dti-1338	247	20	ligament	ligament	NOUN
dti-1338	247	21	cells	cell	NOUN
dti-1338	247	22	on	on	ADP
dti-1338	247	23	synthetic	synthetic	ADJ
dti-1338	247	24	biominerals	biomineral	NOUN
dti-1338	247	25	.	.	PUNCT
dti-1338	248	1	oral	oral	ADJ
dti-1338	248	2	dis	dis	PROPN
dti-1338	248	3	.	.	PUNCT
dti-1338	249	1	2007;13(5):500–6	2007;13(5):500–6	NUM
dti-1338	249	2	.	.	PUNCT
dti-1338	249	3	http://www.la-press.com	http://www.la-press.com	X
dti-1338	249	4	publish	publish	VERB
dti-1338	249	5	with	with	ADP
dti-1338	249	6	libertas	liberta	NOUN
dti-1338	249	7	academica	academica	PROPN
dti-1338	249	8	and	and	CCONJ
dti-1338	249	9	every	every	DET
dti-1338	249	10	scientist	scientist	NOUN
dti-1338	249	11	working	work	VERB
dti-1338	249	12	in	in	ADP
dti-1338	249	13	your	your	PRON
dti-1338	249	14	field	field	NOUN
dti-1338	249	15	can	can	AUX
dti-1338	249	16	read	read	VERB
dti-1338	249	17	your	your	PRON
dti-1338	249	18	article	article	NOUN
dti-1338	249	19	“	"	PUNCT
dti-1338	249	20	i	i	PRON
dti-1338	249	21	would	would	AUX
dti-1338	249	22	like	like	VERB
dti-1338	249	23	to	to	PART
dti-1338	249	24	say	say	VERB
dti-1338	249	25	that	that	SCONJ
dti-1338	249	26	this	this	PRON
dti-1338	249	27	is	be	AUX
dti-1338	249	28	the	the	DET
dti-1338	249	29	most	most	ADV
dti-1338	249	30	author	author	NOUN
dti-1338	249	31	-	-	PUNCT
dti-1338	249	32	friendly	friendly	ADJ
dti-1338	249	33	editing	editing	NOUN
dti-1338	249	34	process	process	NOUN
dti-1338	249	35	i	i	PRON
dti-1338	249	36	have	have	AUX
dti-1338	249	37	experienced	experience	VERB
dti-1338	249	38	in	in	ADP
dti-1338	249	39	over	over	ADP
dti-1338	249	40	150	150	NUM
dti-1338	249	41	publications	publication	NOUN
dti-1338	249	42	.	.	PUNCT
dti-1338	250	1	thank	thank	VERB
dti-1338	250	2	you	you	PRON
dti-1338	250	3	most	most	ADV
dti-1338	250	4	sincerely	sincerely	ADV
dti-1338	250	5	.	.	PUNCT
dti-1338	250	6	”	"	PUNCT
dti-1338	251	1	“	"	PUNCT
dti-1338	251	2	the	the	DET
dti-1338	251	3	communication	communication	NOUN
dti-1338	251	4	between	between	ADP
dti-1338	251	5	your	your	PRON
dti-1338	251	6	staff	staff	NOUN
dti-1338	251	7	and	and	CCONJ
dti-1338	251	8	me	i	PRON
dti-1338	251	9	has	have	AUX
dti-1338	251	10	been	be	AUX
dti-1338	251	11	terrific	terrific	ADJ
dti-1338	251	12	.	.	PUNCT
dti-1338	252	1	whenever	whenever	SCONJ
dti-1338	252	2	progress	progress	NOUN
dti-1338	252	3	is	be	AUX
dti-1338	252	4	made	make	VERB
dti-1338	252	5	with	with	ADP
dti-1338	252	6	the	the	DET
dti-1338	252	7	manuscript	manuscript	NOUN
dti-1338	252	8	,	,	PUNCT
dti-1338	252	9	i	i	PRON
dti-1338	252	10	receive	receive	VERB
dti-1338	252	11	notice	notice	NOUN
dti-1338	252	12	.	.	PUNCT
dti-1338	253	1	quite	quite	ADV
dti-1338	253	2	honestly	honestly	ADV
dti-1338	253	3	,	,	PUNCT
dti-1338	253	4	i	i	PRON
dti-1338	253	5	’ve	’ve	AUX
dti-1338	253	6	never	never	ADV
dti-1338	253	7	had	have	VERB
dti-1338	253	8	such	such	ADJ
dti-1338	253	9	complete	complete	ADJ
dti-1338	253	10	communication	communication	NOUN
dti-1338	253	11	with	with	ADP
dti-1338	253	12	a	a	DET
dti-1338	253	13	journal	journal	NOUN
dti-1338	253	14	.	.	PUNCT
dti-1338	253	15	”	"	PUNCT
dti-1338	254	1	“	"	PUNCT
dti-1338	254	2	la	la	X
dti-1338	254	3	is	be	AUX
dti-1338	254	4	different	different	ADJ
dti-1338	254	5	,	,	PUNCT
dti-1338	254	6	and	and	CCONJ
dti-1338	254	7	hopefully	hopefully	ADV
dti-1338	254	8	represents	represent	VERB
dti-1338	254	9	a	a	DET
dti-1338	254	10	kind	kind	NOUN
dti-1338	254	11	of	of	ADP
dti-1338	254	12	scientific	scientific	ADJ
dti-1338	254	13	publication	publication	NOUN
dti-1338	254	14	machinery	machinery	NOUN
dti-1338	254	15	that	that	PRON
dti-1338	254	16	removes	remove	VERB
dti-1338	254	17	the	the	DET
dti-1338	254	18	hurdles	hurdle	NOUN
dti-1338	254	19	from	from	ADP
dti-1338	254	20	free	free	ADJ
dti-1338	254	21	flow	flow	NOUN
dti-1338	254	22	of	of	ADP
dti-1338	254	23	scientific	scientific	ADJ
dti-1338	254	24	thought	thought	NOUN
dti-1338	254	25	.	.	PUNCT
dti-1338	254	26	”	"	PUNCT
dti-1338	255	1	your	your	PRON
dti-1338	255	2	paper	paper	NOUN
dti-1338	255	3	will	will	AUX
dti-1338	255	4	be	be	AUX
dti-1338	255	5	:	:	PUNCT
dti-1338	255	6	•	•	ADV
dti-1338	255	7	available	available	ADJ
dti-1338	255	8	to	to	ADP
dti-1338	255	9	your	your	PRON
dti-1338	255	10	entire	entire	ADJ
dti-1338	255	11	community	community	NOUN
dti-1338	255	12	free	free	ADJ
dti-1338	255	13	of	of	ADP
dti-1338	255	14	charge	charge	NOUN
dti-1338	255	15	•	•	ADV
dti-1338	255	16	fairly	fairly	ADV
dti-1338	255	17	and	and	CCONJ
dti-1338	255	18	quickly	quickly	ADV
dti-1338	255	19	peer	peer	NOUN
dti-1338	255	20	reviewed	review	VERB
dti-1338	255	21	•	•	NOUN
dti-1338	255	22	yours	yours	PRON
dti-1338	255	23	!	!	PUNCT
dti-1338	256	1	you	you	PRON
dti-1338	256	2	retain	retain	VERB
dti-1338	256	3	copyright	copyright	NOUN
dti-1338	256	4	http://www.la-press.com	http://www.la-press.com	X
dti-1338	257	1	the	the	DET
dti-1338	257	2	effect	effect	NOUN
dti-1338	257	3	of	of	ADP
dti-1338	257	4	vpa	vpa	PROPN
dti-1338	257	5	on	on	ADP
dti-1338	257	6	mesenchymal	mesenchymal	ADJ
dti-1338	257	7	cell	cell	NOUN
dti-1338	257	8	in	in	ADP
dti-1338	257	9	ecm	ecm	PROPN
dti-1338	257	10	drug	drug	NOUN
dti-1338	257	11	target	target	NOUN
dti-1338	257	12	insights	insight	NOUN
dti-1338	257	13	2011:5	2011:5	NUM
dti-1338	257	14	9	9	NUM
dti-1338	257	15	15	15	NUM
dti-1338	257	16	.	.	PUNCT
dti-1338	258	1	huojia	huojia	PROPN
dti-1338	258	2	m	m	PROPN
dti-1338	258	3	,	,	PUNCT
dti-1338	258	4	muraoka	muraoka	PROPN
dti-1338	258	5	n	n	CCONJ
dti-1338	258	6	,	,	PUNCT
dti-1338	258	7	yoshizaki	yoshizaki	PROPN
dti-1338	258	8	k	k	NOUN
dti-1338	258	9	,	,	PUNCT
dti-1338	258	10	fukumoto	fukumoto	PRON
dti-1338	258	11	s	s	PROPN
dti-1338	258	12	,	,	PUNCT
dti-1338	258	13	et	et	PROPN
dti-1338	258	14	al	al	PROPN
dti-1338	258	15	.	.	PUNCT
dti-1338	258	16	tgf	tgf	PROPN
dti-1338	258	17	-	-	PUNCT
dti-1338	258	18	beta3	beta3	NOUN
dti-1338	258	19	induces	induce	VERB
dti-1338	258	20	ectopic	ectopic	ADJ
dti-1338	258	21	mineralization	mineralization	NOUN
dti-1338	258	22	in	in	ADP
dti-1338	258	23	fetal	fetal	ADJ
dti-1338	258	24	mouse	mouse	NOUN
dti-1338	258	25	dental	dental	ADJ
dti-1338	258	26	pulp	pulp	NOUN
dti-1338	258	27	during	during	ADP
dti-1338	258	28	tooth	tooth	NOUN
dti-1338	258	29	germ	germ	NOUN
dti-1338	258	30	development	development	NOUN
dti-1338	258	31	.	.	PUNCT
dti-1338	259	1	dev	dev	PROPN
dti-1338	259	2	growth	growth	NOUN
dti-1338	259	3	differ	differ	VERB
dti-1338	259	4	.	.	PUNCT
dti-1338	260	1	2005;47(3):141–52	2005;47(3):141–52	NUM
dti-1338	260	2	.	.	NOUN
dti-1338	261	1	16	16	NUM
dti-1338	261	2	.	.	PUNCT
dti-1338	262	1	takahashi	takahashi	PROPN
dti-1338	262	2	a	a	PROPN
dti-1338	262	3	,	,	PUNCT
dti-1338	262	4	onodera	onodera	NOUN
dti-1338	262	5	k.	k.	PROPN
dti-1338	262	6	valproic	valproic	PROPN
dti-1338	262	7	acid	acid	PROPN
dti-1338	262	8	induced	induce	VERB
dti-1338	262	9	osteopenia	osteopenia	NOUN
dti-1338	262	10	and	and	CCONJ
dti-1338	262	11	its	its	PRON
dti-1338	262	12	prevention	prevention	NOUN
dti-1338	262	13	with	with	ADP
dti-1338	262	14	alfacalcidol	alfacalcidol	NOUN
dti-1338	262	15	and	and	CCONJ
dti-1338	262	16	alendronate	alendronate	NOUN
dti-1338	262	17	.	.	PUNCT
dti-1338	263	1	j	j	PROPN
dti-1338	263	2	hard	hard	ADJ
dti-1338	263	3	tissue	tissue	NOUN
dti-1338	263	4	biology	biology	NOUN
dti-1338	263	5	.	.	PUNCT
dti-1338	264	1	2005	2005	NUM
dti-1338	264	2	;	;	PUNCT
dti-1338	265	1	14(2):275–6	14(2):275–6	NUM
dti-1338	265	2	.	.	PUNCT
dti-1338	266	1	17	17	NUM
dti-1338	266	2	.	.	PUNCT
dti-1338	267	1	walmod	walmod	PROPN
dti-1338	267	2	ps	ps	PROPN
dti-1338	267	3	,	,	PUNCT
dti-1338	267	4	skladchikova	skladchikova	X
dti-1338	267	5	g	g	PROPN
dti-1338	267	6	,	,	PUNCT
dti-1338	267	7	kawa	kawa	PROPN
dti-1338	267	8	a	a	X
dti-1338	267	9	,	,	PUNCT
dti-1338	267	10	berezin	berezin	PROPN
dti-1338	267	11	v	v	NOUN
dti-1338	267	12	,	,	PUNCT
dti-1338	267	13	bock	bock	NOUN
dti-1338	267	14	e.	e.	PROPN
dti-1338	268	1	antiepileptic	antiepileptic	PROPN
dti-1338	268	2	teratogen	teratogen	NOUN
dti-1338	268	3	valproic	valproic	ADJ
dti-1338	268	4	acid	acid	NOUN
dti-1338	268	5	(	(	PUNCT
dti-1338	268	6	vpa	vpa	PROPN
dti-1338	268	7	)	)	PUNCT
dti-1338	268	8	modulates	modulate	NOUN
dti-1338	268	9	organization	organization	NOUN
dti-1338	268	10	and	and	CCONJ
dti-1338	268	11	dynamics	dynamic	NOUN
dti-1338	268	12	of	of	ADP
dti-1338	268	13	the	the	DET
dti-1338	268	14	actin	actin	NOUN
dti-1338	268	15	cytoskeleton	cytoskeleton	PROPN
dti-1338	268	16	.	.	PUNCT
dti-1338	269	1	cell	cell	NOUN
dti-1338	269	2	motil	motil	PROPN
dti-1338	269	3	cytoskeleton	cytoskeleton	PROPN
dti-1338	269	4	.	.	PUNCT
dti-1338	270	1	1999;42(3):241–55	1999;42(3):241–55	NUM
dti-1338	270	2	.	.	PUNCT
dti-1338	270	3	18	18	NUM
dti-1338	270	4	.	.	PUNCT
dti-1338	270	5	fuller	full	ADJ
dti-1338	270	6	lc	lc	PROPN
dti-1338	270	7	,	,	PUNCT
dti-1338	270	8	cornelius	cornelius	PROPN
dti-1338	270	9	sk	sk	PROPN
dti-1338	270	10	,	,	PUNCT
dti-1338	270	11	murphy	murphy	PROPN
dti-1338	270	12	cw	cw	PROPN
dti-1338	270	13	,	,	PUNCT
dti-1338	270	14	wiens	wiens	PROPN
dti-1338	270	15	dj	dj	PROPN
dti-1338	270	16	.	.	PROPN
dti-1338	270	17	neural	neural	ADJ
dti-1338	270	18	crest	crest	PROPN
dti-1338	270	19	cell	cell	NOUN
dti-1338	270	20	motility	motility	NOUN
dti-1338	270	21	in	in	ADP
dti-1338	270	22	valproic	valproic	ADJ
dti-1338	270	23	acid	acid	NOUN
dti-1338	270	24	.	.	PUNCT
dti-1338	271	1	reprod	reprod	PROPN
dti-1338	271	2	toxicol	toxicol	PROPN
dti-1338	271	3	.	.	PUNCT
dti-1338	272	1	2002;16(6):825–39	2002;16(6):825–39	NUM
dti-1338	272	2	.	.	PUNCT
dti-1338	273	1	19	19	NUM
dti-1338	273	2	.	.	X
dti-1338	273	3	terranova	terranova	PROPN
dti-1338	273	4	vp	vp	PROPN
dti-1338	273	5	,	,	PUNCT
dti-1338	273	6	aumailley	aumailley	PROPN
dti-1338	273	7	m	m	PRON
dti-1338	273	8	,	,	PUNCT
dti-1338	273	9	sultan	sultan	PROPN
dti-1338	273	10	lh	lh	PROPN
dti-1338	273	11	,	,	PUNCT
dti-1338	273	12	martin	martin	PROPN
dti-1338	273	13	gr	gr	PROPN
dti-1338	273	14	,	,	PUNCT
dti-1338	273	15	kleinman	kleinman	PROPN
dti-1338	273	16	hk	hk	PROPN
dti-1338	273	17	.	.	PUNCT
dti-1338	274	1	regulation	regulation	NOUN
dti-1338	274	2	of	of	ADP
dti-1338	274	3	cell	cell	NOUN
dti-1338	274	4	attachment	attachment	NOUN
dti-1338	274	5	and	and	CCONJ
dti-1338	274	6	cell	cell	NOUN
dti-1338	274	7	number	number	NOUN
dti-1338	274	8	by	by	ADP
dti-1338	274	9	fibronectin	fibronectin	NOUN
dti-1338	274	10	and	and	CCONJ
dti-1338	274	11	laminin	laminin	NOUN
dti-1338	274	12	.	.	PUNCT
dti-1338	275	1	j	j	PROPN
dti-1338	275	2	cell	cell	NOUN
dti-1338	275	3	physiol	physiol	PROPN
dti-1338	275	4	.	.	PUNCT
dti-1338	276	1	1986;127(3):473–9	1986;127(3):473–9	NUM
dti-1338	276	2	.	.	PUNCT
dti-1338	277	1	20	20	NUM
dti-1338	277	2	.	.	PUNCT
dti-1338	278	1	george	george	PROPN
dti-1338	278	2	j	j	PROPN
dti-1338	278	3	,	,	PUNCT
dti-1338	278	4	kuboki	kuboki	PROPN
dti-1338	278	5	y	y	PROPN
dti-1338	278	6	,	,	PUNCT
dti-1338	278	7	miyata	miyata	NOUN
dti-1338	278	8	t.	t.	ADJ
dti-1338	278	9	differentiation	differentiation	NOUN
dti-1338	278	10	of	of	ADP
dti-1338	278	11	mesenchymal	mesenchymal	ADJ
dti-1338	278	12	stem	stem	NOUN
dti-1338	278	13	cells	cell	NOUN
dti-1338	278	14	into	into	ADP
dti-1338	278	15	osteoblasts	osteoblast	NOUN
dti-1338	278	16	on	on	ADP
dti-1338	278	17	honeycomb	honeycomb	NOUN
dti-1338	278	18	collagen	collagen	NOUN
dti-1338	278	19	scaffolds	scaffold	NOUN
dti-1338	278	20	.	.	PUNCT
dti-1338	279	1	biotechnol	biotechnol	PROPN
dti-1338	279	2	bioeng	bioeng	PROPN
dti-1338	279	3	.	.	PUNCT
dti-1338	280	1	2006	2006	NUM
dti-1338	280	2	;	;	PUNCT
dti-1338	280	3	20;95(3):404–11	20;95(3):404–11	NUM
dti-1338	280	4	.	.	X
dti-1338	281	1	21	21	NUM
dti-1338	281	2	.	.	PUNCT
dti-1338	282	1	cheng	cheng	PROPN
dti-1338	282	2	sl	sl	PROPN
dti-1338	282	3	,	,	PUNCT
dti-1338	282	4	yang	yang	PROPN
dti-1338	282	5	jw	jw	PROPN
dti-1338	282	6	,	,	PUNCT
dti-1338	282	7	rifas	rifas	PROPN
dti-1338	282	8	l	l	PROPN
dti-1338	282	9	,	,	PUNCT
dti-1338	282	10	zhang	zhang	PROPN
dti-1338	282	11	sf	sf	PROPN
dti-1338	282	12	,	,	PUNCT
dti-1338	282	13	avioli	avioli	PROPN
dti-1338	282	14	lv	lv	PROPN
dti-1338	282	15	.	.	PUNCT
dti-1338	283	1	differentiation	differentiation	NOUN
dti-1338	283	2	of	of	ADP
dti-1338	283	3	human	human	ADJ
dti-1338	283	4	bone	bone	NOUN
dti-1338	283	5	marrow	marrow	PROPN
dti-1338	283	6	osteogenic	osteogenic	ADJ
dti-1338	283	7	stromal	stromal	ADJ
dti-1338	283	8	cells	cell	NOUN
dti-1338	283	9	in	in	ADP
dti-1338	283	10	vitro	vitro	NOUN
dti-1338	283	11	:	:	PUNCT
dti-1338	283	12	induction	induction	NOUN
dti-1338	283	13	of	of	ADP
dti-1338	283	14	the	the	DET
dti-1338	283	15	osteoblast	osteoblast	ADJ
dti-1338	283	16	phenotype	phenotype	NOUN
dti-1338	283	17	by	by	ADP
dti-1338	283	18	dexamethasone	dexamethasone	NOUN
dti-1338	283	19	.	.	PUNCT
dti-1338	284	1	endocrinology	endocrinology	NOUN
dti-1338	284	2	.	.	PUNCT
dti-1338	285	1	1994;134(1):277–86	1994;134(1):277–86	NUM
dti-1338	285	2	.	.	PUNCT
dti-1338	286	1	22	22	NUM
dti-1338	286	2	.	.	PUNCT
dti-1338	287	1	shea	shea	PROPN
dti-1338	287	2	cm	cm	PROPN
dti-1338	287	3	,	,	PUNCT
dti-1338	287	4	edgar	edgar	PROPN
dti-1338	287	5	cm	cm	PROPN
dti-1338	287	6	,	,	PUNCT
dti-1338	287	7	einhorn	einhorn	PROPN
dti-1338	287	8	ta	ta	PROPN
dti-1338	287	9	,	,	PUNCT
dti-1338	287	10	gerstenfeld	gerstenfeld	VERB
dti-1338	287	11	lc	lc	PROPN
dti-1338	287	12	.	.	PUNCT
dti-1338	288	1	bmp	bmp	PROPN
dti-1338	288	2	treatment	treatment	NOUN
dti-1338	288	3	of	of	ADP
dti-1338	288	4	c3h10t1/2	c3h10t1/2	PROPN
dti-1338	288	5	mesenchymal	mesenchymal	NOUN
dti-1338	288	6	stem	stem	NOUN
dti-1338	288	7	cells	cell	NOUN
dti-1338	288	8	induces	induce	VERB
dti-1338	288	9	both	both	CCONJ
dti-1338	288	10	chondrogenesis	chondrogenesis	NOUN
dti-1338	288	11	and	and	CCONJ
dti-1338	288	12	osteogenesis	osteogenesis	NOUN
dti-1338	288	13	.	.	PUNCT
dti-1338	289	1	j	j	PROPN
dti-1338	289	2	cell	cell	PROPN
dti-1338	289	3	biochem	biochem	PROPN
dti-1338	289	4	.	.	PUNCT
dti-1338	290	1	2003;15;90(6):1112–27	2003;15;90(6):1112–27	X
dti-1338	290	2	.	.	PROPN
dti-1338	290	3	23	23	NUM
dti-1338	290	4	.	.	PUNCT
dti-1338	291	1	makhijani	makhijani	PROPN
dti-1338	291	2	ns	ns	PROPN
dti-1338	291	3	,	,	PUNCT
dti-1338	291	4	bischoff	bischoff	NOUN
dti-1338	291	5	ds	ds	PROPN
dti-1338	291	6	,	,	PUNCT
dti-1338	291	7	yamaguchi	yamaguchi	PROPN
dti-1338	291	8	dt	dt	PROPN
dti-1338	291	9	.	.	PUNCT
dti-1338	292	1	regulation	regulation	NOUN
dti-1338	292	2	of	of	ADP
dti-1338	292	3	proliferation	proliferation	NOUN
dti-1338	292	4	and	and	CCONJ
dti-1338	292	5	migration	migration	NOUN
dti-1338	292	6	in	in	ADP
dti-1338	292	7	retinoic	retinoic	PROPN
dti-1338	292	8	acid	acid	PROPN
dti-1338	292	9	treated	treat	VERB
dti-1338	292	10	c3h10t1/2	c3h10t1/2	PROPN
dti-1338	292	11	cells	cell	NOUN
dti-1338	292	12	by	by	ADP
dti-1338	292	13	tgf	tgf	PROPN
dti-1338	292	14	-	-	PUNCT
dti-1338	292	15	beta	beta	NOUN
dti-1338	292	16	isoforms	isoform	NOUN
dti-1338	292	17	.	.	PUNCT
dti-1338	293	1	j	j	PROPN
dti-1338	293	2	cell	cell	NOUN
dti-1338	293	3	physiol	physiol	PROPN
dti-1338	293	4	.	.	PUNCT
dti-1338	294	1	2005;202(1):304–13	2005;202(1):304–13	NUM
dti-1338	294	2	.	.	PUNCT
dti-1338	294	3	http://www.la-press.com	http://www.la-press.com	X
dti-1338	294	4	http://www.la-press.com	http://www.la-press.com	X