id	sid	tid	token	lemma	pos
dti-1352	1	1	11drug	11drug	PROPN
dti-1352	1	2	target	target	NOUN
dti-1352	1	3	insights	insight	VERB
dti-1352	1	4	2014:8	2014:8	NUM
dti-1352	1	5	open	open	ADJ
dti-1352	1	6	access	access	NOUN
dti-1352	1	7	:	:	PUNCT
dti-1352	1	8	full	full	ADJ
dti-1352	1	9	open	open	ADJ
dti-1352	1	10	access	access	NOUN
dti-1352	1	11	to	to	ADP
dti-1352	1	12	this	this	PRON
dti-1352	1	13	and	and	CCONJ
dti-1352	1	14	thousands	thousand	NOUN
dti-1352	1	15	of	of	ADP
dti-1352	1	16	other	other	ADJ
dti-1352	1	17	papers	paper	NOUN
dti-1352	1	18	at	at	ADP
dti-1352	1	19	http://www.la-press.com	http://www.la-press.com	X
dti-1352	1	20	.	.	PUNCT
dti-1352	2	1	drug	drug	NOUN
dti-1352	2	2	target	target	NOUN
dti-1352	2	3	insights	insight	NOUN
dti-1352	2	4	introduction	introduction	VERB
dti-1352	2	5	several	several	ADJ
dti-1352	2	6	lines	line	NOUN
dti-1352	2	7	of	of	ADP
dti-1352	2	8	evidence	evidence	NOUN
dti-1352	2	9	have	have	AUX
dti-1352	2	10	suggested	suggest	VERB
dti-1352	2	11	that	that	SCONJ
dti-1352	2	12	impaired	impaired	ADJ
dti-1352	2	13	cognition	cognition	NOUN
dti-1352	2	14	is	be	AUX
dti-1352	2	15	an	an	DET
dti-1352	2	16	element	element	NOUN
dti-1352	2	17	of	of	ADP
dti-1352	2	18	depression	depression	NOUN
dti-1352	2	19	and	and	CCONJ
dti-1352	2	20	that	that	DET
dti-1352	2	21	antidepressant	antidepressant	ADJ
dti-1352	2	22	therapy	therapy	NOUN
dti-1352	2	23	may	may	AUX
dti-1352	2	24	improve	improve	VERB
dti-1352	2	25	cognitive	cognitive	ADJ
dti-1352	2	26	function.1	function.1	NOUN
dti-1352	2	27	classic	classic	ADJ
dti-1352	2	28	antidepressants	antidepressant	NOUN
dti-1352	2	29	with	with	ADP
dti-1352	2	30	a	a	DET
dti-1352	2	31	central	central	ADJ
dti-1352	2	32	monoaminergic	monoaminergic	ADJ
dti-1352	2	33	function	function	NOUN
dti-1352	2	34	are	be	AUX
dti-1352	2	35	associated	associate	VERB
dti-1352	2	36	with	with	ADP
dti-1352	2	37	a	a	DET
dti-1352	2	38	delayed	delay	VERB
dti-1352	2	39	therapeutic	therapeutic	ADJ
dti-1352	2	40	response	response	NOUN
dti-1352	2	41	and	and	CCONJ
dti-1352	2	42	side	side	NOUN
dti-1352	2	43	effects	effect	NOUN
dti-1352	2	44	,	,	PUNCT
dti-1352	2	45	thereby	thereby	ADV
dti-1352	2	46	limiting	limit	VERB
dti-1352	2	47	their	their	PRON
dti-1352	2	48	usage	usage	NOUN
dti-1352	2	49	.	.	PUNCT
dti-1352	3	1	although	although	SCONJ
dti-1352	3	2	the	the	DET
dti-1352	3	3	pathology	pathology	NOUN
dti-1352	3	4	of	of	ADP
dti-1352	3	5	depression	depression	NOUN
dti-1352	3	6	and	and	CCONJ
dti-1352	3	7	the	the	DET
dti-1352	3	8	mechanism	mechanism	NOUN
dti-1352	3	9	of	of	ADP
dti-1352	3	10	action	action	NOUN
dti-1352	3	11	of	of	ADP
dti-1352	3	12	antidepressant	antidepressant	ADJ
dti-1352	3	13	drugs	drug	NOUN
dti-1352	3	14	are	be	AUX
dti-1352	3	15	well	well	ADV
dti-1352	3	16	known	know	VERB
dti-1352	3	17	,	,	PUNCT
dti-1352	3	18	the	the	DET
dti-1352	3	19	adequacy	adequacy	NOUN
dti-1352	3	20	of	of	ADP
dti-1352	3	21	current	current	ADJ
dti-1352	3	22	antidepressant	antidepressant	ADJ
dti-1352	3	23	targets	target	NOUN
dti-1352	3	24	is	be	AUX
dti-1352	3	25	questionable	questionable	ADJ
dti-1352	3	26	.	.	PUNCT
dti-1352	4	1	stress	stress	NOUN
dti-1352	4	2	is	be	AUX
dti-1352	4	3	an	an	DET
dti-1352	4	4	important	important	ADJ
dti-1352	4	5	risk	risk	NOUN
dti-1352	4	6	factor	factor	NOUN
dti-1352	4	7	in	in	ADP
dti-1352	4	8	the	the	DET
dti-1352	4	9	development	development	NOUN
dti-1352	4	10	of	of	ADP
dti-1352	4	11	depression,2	depression,2	ADJ
dti-1352	4	12	and	and	CCONJ
dti-1352	4	13	stress	stress	NOUN
dti-1352	4	14	-	-	PUNCT
dti-1352	4	15	induced	induce	VERB
dti-1352	4	16	memory	memory	NOUN
dti-1352	4	17	impairments	impairment	NOUN
dti-1352	4	18	are	be	AUX
dti-1352	4	19	commonly	commonly	ADV
dti-1352	4	20	reported.3	reported.3	ADJ
dti-1352	4	21	therefore	therefore	ADV
dti-1352	4	22	,	,	PUNCT
dti-1352	4	23	the	the	DET
dti-1352	4	24	use	use	NOUN
dti-1352	4	25	of	of	ADP
dti-1352	4	26	an	an	DET
dti-1352	4	27	antidepressant	antidepressant	NOUN
dti-1352	4	28	to	to	PART
dti-1352	4	29	ameliorate	ameliorate	VERB
dti-1352	4	30	stress	stress	NOUN
dti-1352	4	31	-	-	PUNCT
dti-1352	4	32	induced	induce	VERB
dti-1352	4	33	cognitive	cognitive	ADJ
dti-1352	4	34	deficits	deficit	NOUN
dti-1352	4	35	is	be	AUX
dti-1352	4	36	of	of	ADP
dti-1352	4	37	therapeutic	therapeutic	ADJ
dti-1352	4	38	relevance	relevance	NOUN
dti-1352	4	39	.	.	PUNCT
dti-1352	5	1	drugs	drug	NOUN
dti-1352	5	2	that	that	PRON
dti-1352	5	3	elevate	elevate	VERB
dti-1352	5	4	the	the	DET
dti-1352	5	5	mood	mood	NOUN
dti-1352	5	6	of	of	ADP
dti-1352	5	7	depressed	depressed	ADJ
dti-1352	5	8	patients	patient	NOUN
dti-1352	5	9	are	be	AUX
dti-1352	5	10	associated	associate	VERB
dti-1352	5	11	with	with	ADP
dti-1352	5	12	synaptic	synaptic	ADJ
dti-1352	5	13	effects	effect	NOUN
dti-1352	5	14	,	,	PUNCT
dti-1352	5	15	that	that	ADV
dti-1352	5	16	is	is	ADV
dti-1352	5	17	,	,	PUNCT
dti-1352	5	18	the	the	DET
dti-1352	5	19	ability	ability	NOUN
dti-1352	5	20	to	to	ADP
dti-1352	5	21	the	the	DET
dti-1352	5	22	antidepressant	antidepressant	ADJ
dti-1352	5	23	agomelatine	agomelatine	NOUN
dti-1352	5	24	improves	improve	VERB
dti-1352	5	25	memory	memory	NOUN
dti-1352	5	26	deterioration	deterioration	NOUN
dti-1352	5	27	and	and	CCONJ
dti-1352	5	28	upregulates	upregulate	VERB
dti-1352	5	29	creb	creb	NOUN
dti-1352	5	30	and	and	CCONJ
dti-1352	5	31	bdnf	bdnf	ADJ
dti-1352	5	32	gene	gene	NOUN
dti-1352	5	33	expression	expression	NOUN
dti-1352	5	34	levels	level	NOUN
dti-1352	5	35	in	in	ADP
dti-1352	5	36	unpredictable	unpredictable	ADJ
dti-1352	5	37	chronic	chronic	ADJ
dti-1352	5	38	mild	mild	ADJ
dti-1352	5	39	stress	stress	NOUN
dti-1352	5	40	(	(	PUNCT
dti-1352	5	41	ucms)-exposed	ucms)-exposed	ADJ
dti-1352	5	42	mice	mouse	NOUN
dti-1352	5	43	esen	esen	ADJ
dti-1352	5	44	gumuslu1	gumuslu1	NOUN
dti-1352	5	45	,	,	PUNCT
dti-1352	5	46	oguz	oguz	PROPN
dti-1352	5	47	mutlu2	mutlu2	PROPN
dti-1352	5	48	,	,	PUNCT
dti-1352	5	49	deniz	deniz	PROPN
dti-1352	5	50	sunnetci1	sunnetci1	PROPN
dti-1352	5	51	,	,	PUNCT
dti-1352	5	52	guner	guner	NOUN
dti-1352	5	53	ulak2	ulak2	PROPN
dti-1352	5	54	,	,	PUNCT
dti-1352	5	55	ipek	ipek	PROPN
dti-1352	5	56	k.	k.	PROPN
dti-1352	5	57	celikyurt2	celikyurt2	PROPN
dti-1352	5	58	,	,	PUNCT
dti-1352	5	59	naci	naci	PROPN
dti-1352	5	60	cine1	cine1	PROPN
dti-1352	5	61	,	,	PUNCT
dti-1352	5	62	furuzan	furuzan	PROPN
dti-1352	5	63	akar2	akar2	PROPN
dti-1352	5	64	,	,	PUNCT
dti-1352	5	65	hakan	hakan	PROPN
dti-1352	5	66	savlı1	savlı1	PROPN
dti-1352	5	67	and	and	CCONJ
dti-1352	5	68	faruk	faruk	PROPN
dti-1352	5	69	erden2	erden2	PROPN
dti-1352	6	1	1department	1department	NUM
dti-1352	6	2	of	of	ADP
dti-1352	6	3	medical	medical	ADJ
dti-1352	6	4	genetics	genetic	NOUN
dti-1352	6	5	,	,	PUNCT
dti-1352	6	6	kocaeli	kocaeli	PROPN
dti-1352	6	7	university	university	PROPN
dti-1352	6	8	medical	medical	ADJ
dti-1352	6	9	faculty	faculty	NOUN
dti-1352	6	10	,	,	PUNCT
dti-1352	6	11	kocaeli	kocaeli	PROPN
dti-1352	6	12	,	,	PUNCT
dti-1352	6	13	turkey	turkey	PROPN
dti-1352	6	14	.	.	PUNCT
dti-1352	7	1	2pharmacology	2pharmacology	NUM
dti-1352	7	2	,	,	PUNCT
dti-1352	7	3	kocaeli	kocaeli	VERB
dti-1352	7	4	university	university	PROPN
dti-1352	7	5	medical	medical	ADJ
dti-1352	7	6	faculty	faculty	NOUN
dti-1352	7	7	,	,	PUNCT
dti-1352	7	8	kocaeli	kocaeli	PROPN
dti-1352	7	9	,	,	PUNCT
dti-1352	7	10	turkey	turkey	PROPN
dti-1352	7	11	.	.	PUNCT
dti-1352	8	1	abstract	abstract	ADJ
dti-1352	8	2	:	:	PUNCT
dti-1352	8	3	agomelatine	agomelatine	PROPN
dti-1352	8	4	,	,	PUNCT
dti-1352	8	5	a	a	DET
dti-1352	8	6	novel	novel	ADJ
dti-1352	8	7	antidepressant	antidepressant	NOUN
dti-1352	8	8	with	with	ADP
dti-1352	8	9	established	establish	VERB
dti-1352	8	10	clinical	clinical	ADJ
dti-1352	8	11	efficacy	efficacy	NOUN
dti-1352	8	12	,	,	PUNCT
dti-1352	8	13	acts	act	VERB
dti-1352	8	14	as	as	ADP
dti-1352	8	15	an	an	DET
dti-1352	8	16	agonist	agonist	NOUN
dti-1352	8	17	of	of	ADP
dti-1352	8	18	melatonergic	melatonergic	NOUN
dti-1352	8	19	mt1	mt1	PROPN
dti-1352	8	20	and	and	CCONJ
dti-1352	8	21	mt2	mt2	ADJ
dti-1352	8	22	receptors	receptor	NOUN
dti-1352	8	23	and	and	CCONJ
dti-1352	8	24	as	as	ADP
dti-1352	8	25	an	an	DET
dti-1352	8	26	antagonist	antagonist	NOUN
dti-1352	8	27	of	of	ADP
dti-1352	8	28	5	5	NUM
dti-1352	8	29	-	-	PUNCT
dti-1352	8	30	ht2c	ht2c	NOUN
dti-1352	8	31	receptors	receptor	NOUN
dti-1352	8	32	.	.	PUNCT
dti-1352	9	1	the	the	DET
dti-1352	9	2	present	present	ADJ
dti-1352	9	3	study	study	NOUN
dti-1352	9	4	was	be	AUX
dti-1352	9	5	undertaken	undertake	VERB
dti-1352	9	6	to	to	PART
dti-1352	9	7	investigate	investigate	VERB
dti-1352	9	8	whether	whether	SCONJ
dti-1352	9	9	chronic	chronic	ADJ
dti-1352	9	10	treatment	treatment	NOUN
dti-1352	9	11	with	with	ADP
dti-1352	9	12	agomelatine	agomelatine	NOUN
dti-1352	9	13	would	would	AUX
dti-1352	9	14	block	block	VERB
dti-1352	9	15	unpredictable	unpredictable	ADJ
dti-1352	9	16	chronic	chronic	ADJ
dti-1352	9	17	mild	mild	ADJ
dti-1352	9	18	stress	stress	NOUN
dti-1352	9	19	(	(	PUNCT
dti-1352	9	20	ucms)-induced	ucms)-induced	ADJ
dti-1352	9	21	cognitive	cognitive	ADJ
dti-1352	9	22	deterioration	deterioration	NOUN
dti-1352	9	23	in	in	ADP
dti-1352	9	24	mice	mouse	NOUN
dti-1352	9	25	in	in	ADP
dti-1352	9	26	passive	passive	ADJ
dti-1352	9	27	avoidance	avoidance	NOUN
dti-1352	9	28	(	(	PUNCT
dti-1352	9	29	pa	pa	PROPN
dti-1352	9	30	)	)	PUNCT
dti-1352	9	31	,	,	PUNCT
dti-1352	9	32	modified	modify	VERB
dti-1352	9	33	elevated	elevated	ADJ
dti-1352	9	34	plus	plus	CCONJ
dti-1352	9	35	maze	maze	NOUN
dti-1352	9	36	(	(	PUNCT
dti-1352	9	37	mepm	mepm	NOUN
dti-1352	9	38	)	)	PUNCT
dti-1352	9	39	,	,	PUNCT
dti-1352	9	40	novel	novel	ADJ
dti-1352	9	41	object	object	NOUN
dti-1352	9	42	recognition	recognition	NOUN
dti-1352	9	43	(	(	PUNCT
dti-1352	9	44	nor	nor	CCONJ
dti-1352	9	45	)	)	PUNCT
dti-1352	9	46	,	,	PUNCT
dti-1352	9	47	and	and	CCONJ
dti-1352	9	48	morris	morris	PROPN
dti-1352	9	49	water	water	PROPN
dti-1352	9	50	maze	maze	NOUN
dti-1352	9	51	(	(	PUNCT
dti-1352	9	52	mwm	mwm	NOUN
dti-1352	9	53	)	)	PUNCT
dti-1352	9	54	tests	test	NOUN
dti-1352	9	55	.	.	PUNCT
dti-1352	10	1	moreover	moreover	ADV
dti-1352	10	2	,	,	PUNCT
dti-1352	10	3	the	the	DET
dti-1352	10	4	effects	effect	NOUN
dti-1352	10	5	of	of	ADP
dti-1352	10	6	stress	stress	NOUN
dti-1352	10	7	and	and	CCONJ
dti-1352	10	8	agomelatine	agomelatine	NOUN
dti-1352	10	9	on	on	ADP
dti-1352	10	10	brain	brain	NOUN
dti-1352	10	11	-	-	PUNCT
dti-1352	10	12	derived	derive	VERB
dti-1352	10	13	neurotrophic	neurotrophic	ADJ
dti-1352	10	14	factor	factor	NOUN
dti-1352	10	15	(	(	PUNCT
dti-1352	10	16	bdnf	bdnf	PROPN
dti-1352	10	17	)	)	PUNCT
dti-1352	10	18	and	and	CCONJ
dti-1352	10	19	cyclic	cyclic	ADJ
dti-1352	10	20	adenosine	adenosine	NOUN
dti-1352	10	21	monophosphate	monophosphate	NOUN
dti-1352	10	22	(	(	PUNCT
dti-1352	10	23	camp	camp	NOUN
dti-1352	10	24	)	)	PUNCT
dti-1352	10	25	response	response	NOUN
dti-1352	10	26	element	element	NOUN
dti-1352	10	27	binding	bind	VERB
dti-1352	10	28	protein	protein	NOUN
dti-1352	10	29	(	(	PUNCT
dti-1352	10	30	creb	creb	NOUN
dti-1352	10	31	)	)	PUNCT
dti-1352	10	32	messenger	messenger	NOUN
dti-1352	10	33	ribonucleic	ribonucleic	ADJ
dti-1352	10	34	acid	acid	PROPN
dti-1352	10	35	(	(	PUNCT
dti-1352	10	36	mrna	mrna	PROPN
dti-1352	10	37	)	)	PUNCT
dti-1352	10	38	levels	level	NOUN
dti-1352	10	39	in	in	ADP
dti-1352	10	40	the	the	DET
dti-1352	10	41	hippocampus	hippocampus	NOUN
dti-1352	10	42	was	be	AUX
dti-1352	10	43	also	also	ADV
dti-1352	10	44	determined	determine	VERB
dti-1352	10	45	using	use	VERB
dti-1352	10	46	quantitative	quantitative	ADJ
dti-1352	10	47	real	real	ADJ
dti-1352	10	48	-	-	PUNCT
dti-1352	10	49	time	time	NOUN
dti-1352	10	50	polymerase	polymerase	NOUN
dti-1352	10	51	chain	chain	NOUN
dti-1352	10	52	reaction	reaction	NOUN
dti-1352	10	53	(	(	PUNCT
dti-1352	10	54	rt	rt	NOUN
dti-1352	10	55	-	-	PUNCT
dti-1352	10	56	pcr	pcr	NOUN
dti-1352	10	57	)	)	PUNCT
dti-1352	10	58	.	.	PUNCT
dti-1352	11	1	male	male	ADJ
dti-1352	11	2	inbred	inbreed	VERB
dti-1352	11	3	balb	balb	NOUN
dti-1352	11	4	/	/	SYM
dti-1352	11	5	c	c	NOUN
dti-1352	11	6	mice	mouse	NOUN
dti-1352	11	7	were	be	AUX
dti-1352	11	8	treated	treat	VERB
dti-1352	11	9	with	with	ADP
dti-1352	11	10	agomelatine	agomelatine	NOUN
dti-1352	11	11	(	(	PUNCT
dti-1352	11	12	10	10	NUM
dti-1352	11	13	mg	mg	NUM
dti-1352	11	14	/	/	SYM
dti-1352	11	15	kg	kg	PROPN
dti-1352	11	16	,	,	PUNCT
dti-1352	11	17	i.p	i.p	PROPN
dti-1352	11	18	.	.	PROPN
dti-1352	11	19	)	)	PUNCT
dti-1352	11	20	,	,	PUNCT
dti-1352	11	21	melatonin	melatonin	NOUN
dti-1352	11	22	(	(	PUNCT
dti-1352	11	23	10	10	NUM
dti-1352	11	24	mg	mg	NUM
dti-1352	11	25	/	/	SYM
dti-1352	11	26	kg	kg	NOUN
dti-1352	11	27	)	)	PUNCT
dti-1352	11	28	,	,	PUNCT
dti-1352	11	29	or	or	CCONJ
dti-1352	11	30	vehicle	vehicle	NOUN
dti-1352	11	31	daily	daily	ADV
dti-1352	11	32	for	for	ADP
dti-1352	11	33	five	five	NUM
dti-1352	11	34	weeks	week	NOUN
dti-1352	11	35	.	.	PUNCT
dti-1352	12	1	the	the	DET
dti-1352	12	2	results	result	NOUN
dti-1352	12	3	of	of	ADP
dti-1352	12	4	this	this	DET
dti-1352	12	5	study	study	NOUN
dti-1352	12	6	revealed	reveal	VERB
dti-1352	12	7	that	that	SCONJ
dti-1352	12	8	ucms	ucms	NOUN
dti-1352	12	9	-	-	PUNCT
dti-1352	12	10	exposed	expose	VERB
dti-1352	12	11	animals	animal	NOUN
dti-1352	12	12	exhibited	exhibit	VERB
dti-1352	12	13	memory	memory	NOUN
dti-1352	12	14	deterioration	deterioration	NOUN
dti-1352	12	15	in	in	ADP
dti-1352	12	16	the	the	DET
dti-1352	12	17	pa	pa	PROPN
dti-1352	12	18	,	,	PUNCT
dti-1352	12	19	mepm	mepm	PROPN
dti-1352	12	20	,	,	PUNCT
dti-1352	12	21	nor	nor	CCONJ
dti-1352	12	22	,	,	PUNCT
dti-1352	12	23	and	and	CCONJ
dti-1352	12	24	mwm	mwm	NOUN
dti-1352	12	25	tests	test	NOUN
dti-1352	12	26	.	.	PUNCT
dti-1352	13	1	the	the	DET
dti-1352	13	2	chronic	chronic	ADJ
dti-1352	13	3	administration	administration	NOUN
dti-1352	13	4	of	of	ADP
dti-1352	13	5	melatonin	melatonin	NOUN
dti-1352	13	6	had	have	VERB
dti-1352	13	7	a	a	DET
dti-1352	13	8	positive	positive	ADJ
dti-1352	13	9	effect	effect	NOUN
dti-1352	13	10	in	in	ADP
dti-1352	13	11	the	the	DET
dti-1352	13	12	pa	pa	PROPN
dti-1352	13	13	and	and	CCONJ
dti-1352	13	14	+	+	PROPN
dti-1352	13	15	mepm	mepm	NOUN
dti-1352	13	16	tests	test	NOUN
dti-1352	13	17	,	,	PUNCT
dti-1352	13	18	whereas	whereas	SCONJ
dti-1352	13	19	agomelatine	agomelatine	PROPN
dti-1352	13	20	had	have	VERB
dti-1352	13	21	a	a	DET
dti-1352	13	22	partial	partial	ADJ
dti-1352	13	23	effect	effect	NOUN
dti-1352	13	24	.	.	PUNCT
dti-1352	14	1	both	both	PRON
dti-1352	14	2	agomelatine	agomelatine	NOUN
dti-1352	14	3	and	and	CCONJ
dti-1352	14	4	melatonin	melatonin	NOUN
dti-1352	14	5	blocked	block	VERB
dti-1352	14	6	stress	stress	NOUN
dti-1352	14	7	-	-	PUNCT
dti-1352	14	8	induced	induce	VERB
dti-1352	14	9	impairment	impairment	NOUN
dti-1352	14	10	in	in	ADP
dti-1352	14	11	visual	visual	ADJ
dti-1352	14	12	memory	memory	NOUN
dti-1352	14	13	in	in	ADP
dti-1352	14	14	the	the	PRON
dti-1352	14	15	nor	nor	CCONJ
dti-1352	14	16	test	test	VERB
dti-1352	14	17	and	and	CCONJ
dti-1352	14	18	reversed	reverse	VERB
dti-1352	14	19	spatial	spatial	ADJ
dti-1352	14	20	learning	learning	NOUN
dti-1352	14	21	and	and	CCONJ
dti-1352	14	22	memory	memory	NOUN
dti-1352	14	23	impairment	impairment	NOUN
dti-1352	14	24	in	in	ADP
dti-1352	14	25	the	the	DET
dti-1352	14	26	stressed	stressed	ADJ
dti-1352	14	27	group	group	NOUN
dti-1352	14	28	in	in	ADP
dti-1352	14	29	the	the	DET
dti-1352	14	30	mwm	mwm	NOUN
dti-1352	14	31	test	test	NOUN
dti-1352	14	32	.	.	PUNCT
dti-1352	15	1	quantitative	quantitative	ADJ
dti-1352	15	2	rt	rt	PROPN
dti-1352	15	3	-	-	PUNCT
dti-1352	15	4	pcr	pcr	PROPN
dti-1352	15	5	revealed	reveal	VERB
dti-1352	15	6	that	that	SCONJ
dti-1352	15	7	creb	creb	NOUN
dti-1352	15	8	and	and	CCONJ
dti-1352	15	9	bdnf	bdnf	ADJ
dti-1352	15	10	gene	gene	NOUN
dti-1352	15	11	expression	expression	NOUN
dti-1352	15	12	levels	level	NOUN
dti-1352	15	13	were	be	AUX
dti-1352	15	14	downregulated	downregulate	VERB
dti-1352	15	15	in	in	ADP
dti-1352	15	16	ucms	ucms	NOUN
dti-1352	15	17	-	-	PUNCT
dti-1352	15	18	exposed	expose	VERB
dti-1352	15	19	mice	mouse	NOUN
dti-1352	15	20	,	,	PUNCT
dti-1352	15	21	and	and	CCONJ
dti-1352	15	22	these	these	DET
dti-1352	15	23	alterations	alteration	NOUN
dti-1352	15	24	were	be	AUX
dti-1352	15	25	reversed	reverse	VERB
dti-1352	15	26	by	by	ADP
dti-1352	15	27	chronic	chronic	ADJ
dti-1352	15	28	agomelatine	agomelatine	NOUN
dti-1352	15	29	or	or	CCONJ
dti-1352	15	30	melatonin	melatonin	NOUN
dti-1352	15	31	treatment	treatment	NOUN
dti-1352	15	32	.	.	PUNCT
dti-1352	16	1	thus	thus	ADV
dti-1352	16	2	,	,	PUNCT
dti-1352	16	3	agomelatine	agomelatine	PROPN
dti-1352	16	4	plays	play	VERB
dti-1352	16	5	an	an	DET
dti-1352	16	6	important	important	ADJ
dti-1352	16	7	role	role	NOUN
dti-1352	16	8	in	in	ADP
dti-1352	16	9	blocking	block	VERB
dti-1352	16	10	stress	stress	NOUN
dti-1352	16	11	-	-	PUNCT
dti-1352	16	12	induced	induce	VERB
dti-1352	16	13	hippocampal	hippocampal	ADJ
dti-1352	16	14	memory	memory	NOUN
dti-1352	16	15	deterioration	deterioration	NOUN
dti-1352	16	16	and	and	CCONJ
dti-1352	16	17	activates	activate	VERB
dti-1352	16	18	molecular	molecular	ADJ
dti-1352	16	19	mechanisms	mechanism	NOUN
dti-1352	16	20	of	of	ADP
dti-1352	16	21	memory	memory	NOUN
dti-1352	16	22	storage	storage	NOUN
dti-1352	16	23	in	in	ADP
dti-1352	16	24	response	response	NOUN
dti-1352	16	25	to	to	ADP
dti-1352	16	26	a	a	DET
dti-1352	16	27	learning	learning	NOUN
dti-1352	16	28	experience	experience	NOUN
dti-1352	16	29	.	.	PUNCT
dti-1352	17	1	keywords	keyword	NOUN
dti-1352	17	2	:	:	PUNCT
dti-1352	17	3	agomelatine	agomelatine	NOUN
dti-1352	17	4	,	,	PUNCT
dti-1352	17	5	melatonin	melatonin	NOUN
dti-1352	17	6	,	,	PUNCT
dti-1352	17	7	depression	depression	NOUN
dti-1352	17	8	,	,	PUNCT
dti-1352	17	9	memory	memory	NOUN
dti-1352	17	10	,	,	PUNCT
dti-1352	17	11	bdnf	bdnf	PROPN
dti-1352	17	12	,	,	PUNCT
dti-1352	17	13	creb	creb	NOUN
dti-1352	17	14	citation	citation	NOUN
dti-1352	17	15	:	:	PUNCT
dti-1352	17	16	gumuslu	gumuslu	NOUN
dti-1352	17	17	et	et	PROPN
dti-1352	17	18	al	al	PROPN
dti-1352	17	19	.	.	PUNCT
dti-1352	18	1	the	the	DET
dti-1352	18	2	antidepressant	antidepressant	ADJ
dti-1352	18	3	agomelatine	agomelatine	NOUN
dti-1352	18	4	improves	improve	VERB
dti-1352	18	5	memory	memory	NOUN
dti-1352	18	6	deterioration	deterioration	NOUN
dti-1352	18	7	and	and	CCONJ
dti-1352	18	8	upregulates	upregulate	VERB
dti-1352	18	9	creb	creb	NOUN
dti-1352	18	10	and	and	CCONJ
dti-1352	18	11	bdnf	bdnf	ADJ
dti-1352	18	12	gene	gene	NOUN
dti-1352	18	13	expression	expression	NOUN
dti-1352	18	14	levels	level	NOUN
dti-1352	18	15	in	in	ADP
dti-1352	18	16	unpredictable	unpredictable	ADJ
dti-1352	18	17	chronic	chronic	ADJ
dti-1352	18	18	mild	mild	ADJ
dti-1352	18	19	stress	stress	NOUN
dti-1352	18	20	(	(	PUNCT
dti-1352	18	21	ucms)-exposed	ucms)-exposed	ADJ
dti-1352	18	22	mice	mouse	NOUN
dti-1352	18	23	.	.	PUNCT
dti-1352	19	1	drug	drug	NOUN
dti-1352	19	2	target	target	NOUN
dti-1352	19	3	insights	insight	VERB
dti-1352	19	4	2014:8	2014:8	NUM
dti-1352	19	5	11–21	11–21	NUM
dti-1352	19	6	doi	doi	NOUN
dti-1352	19	7	:	:	PUNCT
dti-1352	19	8	10.4137	10.4137	NUM
dti-1352	19	9	/	/	SYM
dti-1352	19	10	dti.s13870	dti.s13870	NOUN
dti-1352	19	11	.	.	PUNCT
dti-1352	20	1	received	receive	VERB
dti-1352	20	2	:	:	PUNCT
dti-1352	20	3	december	december	PROPN
dti-1352	20	4	11	11	NUM
dti-1352	20	5	,	,	PUNCT
dti-1352	20	6	2013	2013	NUM
dti-1352	20	7	.	.	PUNCT
dti-1352	21	1	resubmitted	resubmitte	VERB
dti-1352	21	2	:	:	PUNCT
dti-1352	21	3	january	january	PROPN
dti-1352	21	4	19	19	NUM
dti-1352	21	5	,	,	PUNCT
dti-1352	21	6	2014	2014	NUM
dti-1352	21	7	.	.	PUNCT
dti-1352	22	1	accepted	accept	VERB
dti-1352	22	2	for	for	ADP
dti-1352	22	3	publication	publication	NOUN
dti-1352	22	4	:	:	PUNCT
dti-1352	22	5	february	february	PROPN
dti-1352	22	6	6	6	NUM
dti-1352	22	7	,	,	PUNCT
dti-1352	22	8	2014	2014	NUM
dti-1352	22	9	.	.	PUNCT
dti-1352	23	1	academic	academic	ADJ
dti-1352	23	2	editor	editor	NOUN
dti-1352	23	3	:	:	PUNCT
dti-1352	23	4	prithviraj	prithviraj	PROPN
dti-1352	23	5	bose	bose	PROPN
dti-1352	23	6	,	,	PUNCT
dti-1352	23	7	editor	editor	NOUN
dti-1352	23	8	in	in	ADP
dti-1352	23	9	chief	chief	ADJ
dti-1352	23	10	type	type	NOUN
dti-1352	23	11	:	:	PUNCT
dti-1352	23	12	original	original	ADJ
dti-1352	23	13	research	research	NOUN
dti-1352	23	14	funding	funding	NOUN
dti-1352	23	15	:	:	PUNCT
dti-1352	24	1	author(s	author(s	NOUN
dti-1352	24	2	)	)	PUNCT
dti-1352	24	3	disclose	disclose	VERB
dti-1352	24	4	no	no	DET
dti-1352	24	5	funding	funding	NOUN
dti-1352	24	6	sources	source	NOUN
dti-1352	24	7	.	.	PUNCT
dti-1352	25	1	competing	compete	VERB
dti-1352	25	2	interests	interest	NOUN
dti-1352	25	3	:	:	PUNCT
dti-1352	25	4	author(s	author(s	NOUN
dti-1352	25	5	)	)	PUNCT
dti-1352	25	6	disclose	disclose	VERB
dti-1352	25	7	no	no	DET
dti-1352	25	8	potential	potential	ADJ
dti-1352	25	9	conflicts	conflict	NOUN
dti-1352	25	10	of	of	ADP
dti-1352	25	11	interest	interest	NOUN
dti-1352	25	12	.	.	PUNCT
dti-1352	26	1	copyright	copyright	NOUN
dti-1352	26	2	:	:	PUNCT
dti-1352	26	3	©	©	PROPN
dti-1352	26	4	the	the	DET
dti-1352	26	5	authors	author	NOUN
dti-1352	26	6	,	,	PUNCT
dti-1352	26	7	publisher	publisher	NOUN
dti-1352	26	8	and	and	CCONJ
dti-1352	26	9	licensee	licensee	NOUN
dti-1352	26	10	libertas	liberta	NOUN
dti-1352	26	11	academica	academica	PROPN
dti-1352	26	12	limited	limit	VERB
dti-1352	26	13	.	.	PUNCT
dti-1352	27	1	this	this	PRON
dti-1352	27	2	is	be	AUX
dti-1352	27	3	an	an	DET
dti-1352	27	4	open	open	ADJ
dti-1352	27	5	-	-	PUNCT
dti-1352	27	6	access	access	NOUN
dti-1352	27	7	article	article	NOUN
dti-1352	27	8	distributed	distribute	VERB
dti-1352	27	9	under	under	ADP
dti-1352	27	10	the	the	DET
dti-1352	27	11	terms	term	NOUN
dti-1352	27	12	of	of	ADP
dti-1352	27	13	the	the	DET
dti-1352	27	14	creative	creative	ADJ
dti-1352	27	15	commons	common	NOUN
dti-1352	27	16	cc	cc	NOUN
dti-1352	27	17	-	-	PUNCT
dti-1352	27	18	by	by	ADP
dti-1352	27	19	-	-	PUNCT
dti-1352	27	20	nc	nc	PROPN
dti-1352	27	21	3.0	3.0	NUM
dti-1352	27	22	license	license	NOUN
dti-1352	27	23	.	.	PUNCT
dti-1352	28	1	correspondence	correspondence	NOUN
dti-1352	28	2	:	:	PUNCT
dti-1352	29	1	oguzmutlu80@hotmail.com	oguzmutlu80@hotmail.com	X
dti-1352	29	2	http://www.la-press.com	http://www.la-press.com	X
dti-1352	29	3	http://www.la-press.com	http://www.la-press.com	X
dti-1352	30	1	http://dx.doi.org/10.4137/dti.s13870	http://dx.doi.org/10.4137/dti.s13870	PROPN
dti-1352	30	2	mailto:oguzmutlu80@hotmail.com	mailto:oguzmutlu80@hotmail.com	PROPN
dti-1352	30	3	gumuslu	gumuslu	PROPN
dti-1352	30	4	et	et	PROPN
dti-1352	30	5	al	al	PROPN
dti-1352	30	6	12	12	NUM
dti-1352	30	7	drug	drug	NOUN
dti-1352	30	8	target	target	NOUN
dti-1352	30	9	insights	insight	VERB
dti-1352	30	10	2014:8	2014:8	NUM
dti-1352	30	11	increase	increase	VERB
dti-1352	30	12	the	the	DET
dti-1352	30	13	extracellular	extracellular	ADJ
dti-1352	30	14	levels	level	NOUN
dti-1352	30	15	of	of	ADP
dti-1352	30	16	serotonin	serotonin	NOUN
dti-1352	30	17	,	,	PUNCT
dti-1352	30	18	noradrenaline	noradrenaline	ADJ
dti-1352	30	19	,	,	PUNCT
dti-1352	30	20	and	and	CCONJ
dti-1352	30	21	dopamine	dopamine	VERB
dti-1352	30	22	in	in	ADP
dti-1352	30	23	the	the	DET
dti-1352	30	24	brain.4	brain.4	NOUN
dti-1352	30	25	the	the	DET
dti-1352	30	26	monoamine	monoamine	ADJ
dti-1352	30	27	hypothesis	hypothesis	NOUN
dti-1352	30	28	of	of	ADP
dti-1352	30	29	depression	depression	NOUN
dti-1352	30	30	fails	fail	VERB
dti-1352	30	31	to	to	PART
dti-1352	30	32	explain	explain	VERB
dti-1352	30	33	all	all	DET
dti-1352	30	34	the	the	DET
dti-1352	30	35	effects	effect	NOUN
dti-1352	30	36	of	of	ADP
dti-1352	30	37	antidepressants5	antidepressants5	NOUN
dti-1352	30	38	and	and	CCONJ
dti-1352	30	39	receptor	receptor	NOUN
dti-1352	30	40	activation	activation	NOUN
dti-1352	30	41	as	as	ADP
dti-1352	30	42	a	a	DET
dti-1352	30	43	consequence	consequence	NOUN
dti-1352	30	44	of	of	ADP
dti-1352	30	45	the	the	DET
dti-1352	30	46	elevation	elevation	NOUN
dti-1352	30	47	in	in	ADP
dti-1352	30	48	synaptic	synaptic	ADJ
dti-1352	30	49	monoamines	monoamine	NOUN
dti-1352	30	50	,	,	PUNCT
dti-1352	30	51	which	which	PRON
dti-1352	30	52	represent	represent	VERB
dti-1352	30	53	the	the	DET
dti-1352	30	54	primary	primary	ADJ
dti-1352	30	55	molecular	molecular	ADJ
dti-1352	30	56	results	result	NOUN
dti-1352	30	57	of	of	ADP
dti-1352	30	58	antidepressants	antidepressant	NOUN
dti-1352	30	59	.	.	PUNCT
dti-1352	31	1	one	one	NUM
dti-1352	31	2	of	of	ADP
dti-1352	31	3	the	the	DET
dti-1352	31	4	more	more	ADV
dti-1352	31	5	recent	recent	ADJ
dti-1352	31	6	novel	novel	ADJ
dti-1352	31	7	antidepressant	antidepressant	ADJ
dti-1352	31	8	mechanisms	mechanism	NOUN
dti-1352	31	9	identified	identify	VERB
dti-1352	31	10	is	be	AUX
dti-1352	31	11	the	the	DET
dti-1352	31	12	control	control	NOUN
dti-1352	31	13	of	of	ADP
dti-1352	31	14	circadian	circadian	ADJ
dti-1352	31	15	rhythms	rhythm	NOUN
dti-1352	31	16	.	.	PUNCT
dti-1352	32	1	melatonin	melatonin	NOUN
dti-1352	32	2	,	,	PUNCT
dti-1352	32	3	the	the	DET
dti-1352	32	4	major	major	ADJ
dti-1352	32	5	hormone	hormone	NOUN
dti-1352	32	6	of	of	ADP
dti-1352	32	7	the	the	DET
dti-1352	32	8	pineal	pineal	NOUN
dti-1352	32	9	gland	gland	NOUN
dti-1352	32	10	,	,	PUNCT
dti-1352	32	11	is	be	AUX
dti-1352	32	12	an	an	DET
dti-1352	32	13	endogenous	endogenous	ADJ
dti-1352	32	14	agonist	agonist	NOUN
dti-1352	32	15	of	of	ADP
dti-1352	32	16	mt1	mt1	PROPN
dti-1352	32	17	/	/	SYM
dti-1352	32	18	mt2	mt2	ADJ
dti-1352	32	19	receptors	receptor	NOUN
dti-1352	32	20	and	and	CCONJ
dti-1352	32	21	is	be	AUX
dti-1352	32	22	involved	involve	VERB
dti-1352	32	23	in	in	ADP
dti-1352	32	24	the	the	DET
dti-1352	32	25	regulation	regulation	NOUN
dti-1352	32	26	of	of	ADP
dti-1352	32	27	the	the	DET
dti-1352	32	28	sleep	sleep	NOUN
dti-1352	32	29	–	–	PUNCT
dti-1352	32	30	wake	wake	VERB
dti-1352	32	31	cycle	cycle	NOUN
dti-1352	32	32	.	.	PUNCT
dti-1352	33	1	the	the	DET
dti-1352	33	2	recognition	recognition	NOUN
dti-1352	33	3	that	that	SCONJ
dti-1352	33	4	circadian	circadian	PROPN
dti-1352	33	5	rhythm	rhythm	PROPN
dti-1352	33	6	desynchronization	desynchronization	NOUN
dti-1352	33	7	also	also	ADV
dti-1352	33	8	plays	play	VERB
dti-1352	33	9	a	a	DET
dti-1352	33	10	key	key	ADJ
dti-1352	33	11	role	role	NOUN
dti-1352	33	12	in	in	ADP
dti-1352	33	13	mood	mood	NOUN
dti-1352	33	14	disorders	disorder	NOUN
dti-1352	33	15	has	have	AUX
dti-1352	33	16	led	lead	VERB
dti-1352	33	17	to	to	ADP
dti-1352	33	18	the	the	DET
dti-1352	33	19	development	development	NOUN
dti-1352	33	20	of	of	ADP
dti-1352	33	21	agomelatine	agomelatine	NOUN
dti-1352	33	22	.	.	PUNCT
dti-1352	34	1	agomelatine	agomelatine	PROPN
dti-1352	34	2	,	,	PUNCT
dti-1352	34	3	the	the	DET
dti-1352	34	4	first	first	ADJ
dti-1352	34	5	melatonergic	melatonergic	NOUN
dti-1352	34	6	antidepressant	antidepressant	NOUN
dti-1352	34	7	,	,	PUNCT
dti-1352	34	8	is	be	AUX
dti-1352	34	9	an	an	DET
dti-1352	34	10	agonist	agonist	NOUN
dti-1352	34	11	of	of	ADP
dti-1352	34	12	the	the	DET
dti-1352	34	13	melatonergic	melatonergic	NOUN
dti-1352	34	14	mt1	mt1	PROPN
dti-1352	34	15	and	and	CCONJ
dti-1352	34	16	mt2	mt2	PROPN
dti-1352	34	17	receptors6	receptors6	NOUN
dti-1352	34	18	and	and	CCONJ
dti-1352	34	19	an	an	DET
dti-1352	34	20	antagonist	antagonist	NOUN
dti-1352	34	21	of	of	ADP
dti-1352	34	22	the	the	DET
dti-1352	34	23	serotonergic	serotonergic	ADJ
dti-1352	34	24	5	5	NUM
dti-1352	34	25	-	-	SYM
dti-1352	34	26	ht2c	ht2c	NOUN
dti-1352	34	27	receptors,7	receptors,7	ADJ
dti-1352	34	28	and	and	CCONJ
dti-1352	34	29	it	it	PRON
dti-1352	34	30	mimics	mimic	VERB
dti-1352	34	31	the	the	DET
dti-1352	34	32	actions	action	NOUN
dti-1352	34	33	of	of	ADP
dti-1352	34	34	melatonin	melatonin	NOUN
dti-1352	34	35	in	in	ADP
dti-1352	34	36	the	the	DET
dti-1352	34	37	synchronization	synchronization	NOUN
dti-1352	34	38	of	of	ADP
dti-1352	34	39	circadian	circadian	ADJ
dti-1352	34	40	rhythm	rhythm	NOUN
dti-1352	34	41	patterns	pattern	NOUN
dti-1352	34	42	in	in	ADP
dti-1352	34	43	rodents.8	rodents.8	PROPN
dti-1352	34	44	the	the	DET
dti-1352	34	45	antidepressant	antidepressant	ADJ
dti-1352	34	46	-	-	PUNCT
dti-1352	34	47	like	like	ADJ
dti-1352	34	48	activity	activity	NOUN
dti-1352	34	49	of	of	ADP
dti-1352	34	50	agomelatine	agomelatine	NOUN
dti-1352	34	51	is	be	AUX
dti-1352	34	52	attributed	attribute	VERB
dti-1352	34	53	to	to	ADP
dti-1352	34	54	the	the	DET
dti-1352	34	55	synergy	synergy	NOUN
dti-1352	34	56	between	between	ADP
dti-1352	34	57	these	these	DET
dti-1352	34	58	sets	set	NOUN
dti-1352	34	59	of	of	ADP
dti-1352	34	60	receptors	receptor	NOUN
dti-1352	34	61	,	,	PUNCT
dti-1352	34	62	which	which	PRON
dti-1352	34	63	are	be	AUX
dti-1352	34	64	important	important	ADJ
dti-1352	34	65	components	component	NOUN
dti-1352	34	66	of	of	ADP
dti-1352	34	67	the	the	DET
dti-1352	34	68	circadian	circadian	ADJ
dti-1352	34	69	timing	timing	NOUN
dti-1352	34	70	system	system	NOUN
dti-1352	34	71	.	.	PUNCT
dti-1352	35	1	agomelatine	agomelatine	PROPN
dti-1352	35	2	has	have	AUX
dti-1352	35	3	demonstrated	demonstrate	VERB
dti-1352	35	4	antidepressant	antidepressant	ADJ
dti-1352	35	5	-	-	PUNCT
dti-1352	35	6	like	like	ADJ
dti-1352	35	7	activity	activity	NOUN
dti-1352	35	8	in	in	ADP
dti-1352	35	9	several	several	ADJ
dti-1352	35	10	animal	animal	NOUN
dti-1352	35	11	models	model	NOUN
dti-1352	35	12	of	of	ADP
dti-1352	35	13	depression9	depression9	NOUN
dti-1352	35	14	and	and	CCONJ
dti-1352	35	15	in	in	ADP
dti-1352	35	16	a	a	DET
dti-1352	35	17	transgenic	transgenic	NOUN
dti-1352	35	18	mouse	mouse	NOUN
dti-1352	35	19	model	model	NOUN
dti-1352	35	20	of	of	ADP
dti-1352	35	21	depression.10	depression.10	PROPN
dti-1352	35	22	clinically	clinically	ADV
dti-1352	35	23	,	,	PUNCT
dti-1352	35	24	it	it	PRON
dti-1352	35	25	has	have	AUX
dti-1352	35	26	demonstrated	demonstrate	VERB
dti-1352	35	27	efficacy	efficacy	NOUN
dti-1352	35	28	in	in	ADP
dti-1352	35	29	major	major	ADJ
dti-1352	35	30	depressive	depressive	ADJ
dti-1352	35	31	disorders	disorder	NOUN
dti-1352	35	32	in	in	ADP
dti-1352	35	33	several	several	ADJ
dti-1352	35	34	trials.11	trials.11	NOUN
dti-1352	35	35	agomelatine	agomelatine	NOUN
dti-1352	35	36	is	be	AUX
dti-1352	35	37	an	an	DET
dti-1352	35	38	effective	effective	ADJ
dti-1352	35	39	treatment	treatment	NOUN
dti-1352	35	40	for	for	ADP
dti-1352	35	41	depression	depression	NOUN
dti-1352	35	42	because	because	SCONJ
dti-1352	35	43	it	it	PRON
dti-1352	35	44	resynchronizes	resynchronize	VERB
dti-1352	35	45	circadian	circadian	ADJ
dti-1352	35	46	rhythms12	rhythms12	NOUN
dti-1352	35	47	that	that	PRON
dti-1352	35	48	are	be	AUX
dti-1352	35	49	disturbed	disturb	VERB
dti-1352	35	50	in	in	ADP
dti-1352	35	51	depression	depression	NOUN
dti-1352	35	52	.	.	PUNCT
dti-1352	36	1	indeed	indeed	ADV
dti-1352	36	2	,	,	PUNCT
dti-1352	36	3	it	it	PRON
dti-1352	36	4	has	have	AUX
dti-1352	36	5	been	be	AUX
dti-1352	36	6	speculated	speculate	VERB
dti-1352	36	7	for	for	ADP
dti-1352	36	8	a	a	DET
dti-1352	36	9	considerable	considerable	ADJ
dti-1352	36	10	amount	amount	NOUN
dti-1352	36	11	of	of	ADP
dti-1352	36	12	time	time	NOUN
dti-1352	36	13	that	that	SCONJ
dti-1352	36	14	the	the	DET
dti-1352	36	15	disorganization	disorganization	NOUN
dti-1352	36	16	of	of	ADP
dti-1352	36	17	internal	internal	ADJ
dti-1352	36	18	circadian	circadian	ADJ
dti-1352	36	19	rhythms	rhythm	NOUN
dti-1352	36	20	plays	play	VERB
dti-1352	36	21	a	a	DET
dti-1352	36	22	critical	critical	ADJ
dti-1352	36	23	role	role	NOUN
dti-1352	36	24	in	in	ADP
dti-1352	36	25	the	the	DET
dti-1352	36	26	development	development	NOUN
dti-1352	36	27	of	of	ADP
dti-1352	36	28	major	major	ADJ
dti-1352	36	29	depression.13	depression.13	NOUN
dti-1352	36	30	agomelatine	agomelatine	NOUN
dti-1352	36	31	has	have	VERB
dti-1352	36	32	a	a	DET
dti-1352	36	33	favorable	favorable	ADJ
dti-1352	36	34	clinical	clinical	ADJ
dti-1352	36	35	profile	profile	NOUN
dti-1352	36	36	of	of	ADP
dti-1352	36	37	antidepressant	antidepressant	ADJ
dti-1352	36	38	properties	property	NOUN
dti-1352	36	39	and	and	CCONJ
dti-1352	36	40	fewer	few	ADJ
dti-1352	36	41	side	side	ADJ
dti-1352	36	42	effects	effect	NOUN
dti-1352	36	43	than	than	ADP
dti-1352	36	44	traditional	traditional	ADJ
dti-1352	36	45	antidepressants.11	antidepressants.11	NOUN
dti-1352	36	46	unpredictable	unpredictable	ADJ
dti-1352	36	47	chronic	chronic	ADJ
dti-1352	36	48	mild	mild	ADJ
dti-1352	36	49	stress	stress	NOUN
dti-1352	36	50	(	(	PUNCT
dti-1352	36	51	ucms	ucms	NOUN
dti-1352	36	52	)	)	PUNCT
dti-1352	36	53	is	be	AUX
dti-1352	36	54	an	an	DET
dti-1352	36	55	important	important	ADJ
dti-1352	36	56	behavioral	behavioral	ADJ
dti-1352	36	57	model	model	NOUN
dti-1352	36	58	that	that	PRON
dti-1352	36	59	resembles	resemble	VERB
dti-1352	36	60	human	human	ADJ
dti-1352	36	61	depression.14	depression.14	PROPN
dti-1352	36	62	the	the	DET
dti-1352	36	63	hippocampus	hippocampus	NOUN
dti-1352	36	64	and	and	CCONJ
dti-1352	36	65	its	its	PRON
dti-1352	36	66	connections	connection	NOUN
dti-1352	36	67	within	within	ADP
dti-1352	36	68	limbic	limbic	ADJ
dti-1352	36	69	–	–	PUNCT
dti-1352	36	70	cortical	cortical	ADJ
dti-1352	36	71	networks	network	NOUN
dti-1352	36	72	may	may	AUX
dti-1352	36	73	play	play	VERB
dti-1352	36	74	a	a	DET
dti-1352	36	75	crucial	crucial	ADJ
dti-1352	36	76	role	role	NOUN
dti-1352	36	77	in	in	ADP
dti-1352	36	78	the	the	DET
dti-1352	36	79	pathogenesis	pathogenesis	NOUN
dti-1352	36	80	of	of	ADP
dti-1352	36	81	major	major	ADJ
dti-1352	36	82	depression	depression	NOUN
dti-1352	36	83	.	.	PUNCT
dti-1352	37	1	acute	acute	ADJ
dti-1352	37	2	stress	stress	NOUN
dti-1352	37	3	and	and	CCONJ
dti-1352	37	4	chronic	chronic	ADJ
dti-1352	37	5	stress	stress	NOUN
dti-1352	37	6	disturb	disturb	VERB
dti-1352	37	7	hippocampal	hippocampal	NOUN
dti-1352	37	8	-	-	PUNCT
dti-1352	37	9	dependent	dependent	ADJ
dti-1352	37	10	memory	memory	NOUN
dti-1352	37	11	and	and	CCONJ
dti-1352	37	12	prevent	prevent	VERB
dti-1352	37	13	the	the	DET
dti-1352	37	14	formation	formation	NOUN
dti-1352	37	15	of	of	ADP
dti-1352	37	16	longterm	longterm	ADJ
dti-1352	37	17	potentialization	potentialization	NOUN
dti-1352	37	18	,	,	PUNCT
dti-1352	37	19	which	which	PRON
dti-1352	37	20	plays	play	VERB
dti-1352	37	21	a	a	DET
dti-1352	37	22	role	role	NOUN
dti-1352	37	23	in	in	ADP
dti-1352	37	24	the	the	DET
dti-1352	37	25	formation	formation	NOUN
dti-1352	37	26	of	of	ADP
dti-1352	37	27	synaptic	synaptic	ADJ
dti-1352	37	28	plasticity	plasticity	NOUN
dti-1352	37	29	and	and	CCONJ
dti-1352	37	30	memory	memory	NOUN
dti-1352	37	31	.	.	PUNCT
dti-1352	38	1	the	the	DET
dti-1352	38	2	expression	expression	NOUN
dti-1352	38	3	of	of	ADP
dti-1352	38	4	genes	gene	NOUN
dti-1352	38	5	implicated	implicate	VERB
dti-1352	38	6	in	in	ADP
dti-1352	38	7	neuronal	neuronal	ADJ
dti-1352	38	8	plasticity	plasticity	NOUN
dti-1352	38	9	,	,	PUNCT
dti-1352	38	10	such	such	ADJ
dti-1352	38	11	as	as	ADP
dti-1352	38	12	brain	brain	NOUN
dti-1352	38	13	-	-	PUNCT
dti-1352	38	14	derived	derive	VERB
dti-1352	38	15	neurotrophic	neurotrophic	ADJ
dti-1352	38	16	factor	factor	NOUN
dti-1352	38	17	(	(	PUNCT
dti-1352	38	18	bdnf	bdnf	PROPN
dti-1352	38	19	)	)	PUNCT
dti-1352	38	20	and	and	CCONJ
dti-1352	38	21	cyclic	cyclic	ADJ
dti-1352	38	22	adenosine	adenosine	NOUN
dti-1352	38	23	monophosphate	monophosphate	NOUN
dti-1352	38	24	(	(	PUNCT
dti-1352	38	25	camp	camp	NOUN
dti-1352	38	26	)	)	PUNCT
dti-1352	38	27	response	response	NOUN
dti-1352	38	28	element	element	NOUN
dti-1352	38	29	binding	bind	VERB
dti-1352	38	30	protein	protein	NOUN
dti-1352	38	31	(	(	PUNCT
dti-1352	38	32	creb	creb	NOUN
dti-1352	38	33	)	)	PUNCT
dti-1352	38	34	,	,	PUNCT
dti-1352	38	35	have	have	AUX
dti-1352	38	36	been	be	AUX
dti-1352	38	37	shown	show	VERB
dti-1352	38	38	to	to	PART
dti-1352	38	39	be	be	AUX
dti-1352	38	40	downregulated	downregulate	VERB
dti-1352	38	41	in	in	ADP
dti-1352	38	42	stressed	stress	VERB
dti-1352	38	43	mice.15	mice.15	PROPN
dti-1352	38	44	bdnf	bdnf	PROPN
dti-1352	38	45	is	be	AUX
dti-1352	38	46	a	a	DET
dti-1352	38	47	neurotrophin	neurotrophin	NOUN
dti-1352	38	48	that	that	PRON
dti-1352	38	49	modulates	modulate	VERB
dti-1352	38	50	neuronal	neuronal	ADJ
dti-1352	38	51	plasticity	plasticity	NOUN
dti-1352	38	52	,	,	PUNCT
dti-1352	38	53	which	which	PRON
dti-1352	38	54	is	be	AUX
dti-1352	38	55	frequently	frequently	ADV
dti-1352	38	56	associated	associate	VERB
dti-1352	38	57	with	with	ADP
dti-1352	38	58	antidepressant	antidepressant	ADJ
dti-1352	38	59	treatment.16	treatment.16	PROPN
dti-1352	38	60	neurotrophin	neurotrophin	ADJ
dti-1352	38	61	expression	expression	NOUN
dti-1352	38	62	is	be	AUX
dti-1352	38	63	activitydependent17	activitydependent17	NOUN
dti-1352	38	64	and	and	CCONJ
dti-1352	38	65	may	may	AUX
dti-1352	38	66	be	be	AUX
dti-1352	38	67	regulated	regulate	VERB
dti-1352	38	68	by	by	ADP
dti-1352	38	69	the	the	DET
dti-1352	38	70	light	light	ADJ
dti-1352	38	71	and	and	CCONJ
dti-1352	38	72	dark	dark	ADJ
dti-1352	38	73	cycle	cycle	NOUN
dti-1352	38	74	in	in	ADP
dti-1352	38	75	rats18	rats18	NOUN
dti-1352	38	76	and	and	CCONJ
dti-1352	38	77	in	in	ADP
dti-1352	38	78	humans.19	humans.19	PRON
dti-1352	38	79	the	the	DET
dti-1352	38	80	regulation	regulation	NOUN
dti-1352	38	81	of	of	ADP
dti-1352	38	82	the	the	DET
dti-1352	38	83	neurotrophin	neurotrophin	PROPN
dti-1352	38	84	bdnf	bdnf	PROPN
dti-1352	38	85	,	,	PUNCT
dti-1352	38	86	whose	whose	DET
dti-1352	38	87	gene	gene	NOUN
dti-1352	38	88	and	and	CCONJ
dti-1352	38	89	protein	protein	NOUN
dti-1352	38	90	expression	expression	NOUN
dti-1352	38	91	and	and	CCONJ
dti-1352	38	92	function	function	NOUN
dti-1352	38	93	may	may	AUX
dti-1352	38	94	be	be	AUX
dti-1352	38	95	defective	defective	ADJ
dti-1352	38	96	in	in	ADP
dti-1352	38	97	mood	mood	NOUN
dti-1352	38	98	disorders,20	disorders,20	NOUN
dti-1352	38	99	has	have	AUX
dti-1352	38	100	been	be	AUX
dti-1352	38	101	extensively	extensively	ADV
dti-1352	38	102	investigated	investigate	VERB
dti-1352	38	103	in	in	ADP
dti-1352	38	104	recent	recent	ADJ
dti-1352	38	105	years	year	NOUN
dti-1352	38	106	as	as	ADP
dti-1352	38	107	one	one	NUM
dti-1352	38	108	of	of	ADP
dti-1352	38	109	the	the	DET
dti-1352	38	110	mechanisms	mechanism	NOUN
dti-1352	38	111	of	of	ADP
dti-1352	38	112	antidepressants	antidepressant	NOUN
dti-1352	38	113	.	.	PUNCT
dti-1352	39	1	the	the	DET
dti-1352	39	2	modulation	modulation	NOUN
dti-1352	39	3	of	of	ADP
dti-1352	39	4	bdnf	bdnf	PROPN
dti-1352	39	5	represents	represent	VERB
dti-1352	39	6	a	a	DET
dti-1352	39	7	key	key	ADJ
dti-1352	39	8	element	element	NOUN
dti-1352	39	9	in	in	ADP
dti-1352	39	10	long	long	ADJ
dti-1352	39	11	-	-	PUNCT
dti-1352	39	12	term	term	NOUN
dti-1352	39	13	adaptive	adaptive	ADJ
dti-1352	39	14	changes	change	NOUN
dti-1352	39	15	induced	induce	VERB
dti-1352	39	16	by	by	ADP
dti-1352	39	17	antidepressant	antidepressant	ADJ
dti-1352	39	18	drugs	drug	NOUN
dti-1352	39	19	.	.	PUNCT
dti-1352	40	1	moreover	moreover	ADV
dti-1352	40	2	,	,	PUNCT
dti-1352	40	3	such	such	ADJ
dti-1352	40	4	molecular	molecular	ADJ
dti-1352	40	5	analyses	analysis	NOUN
dti-1352	40	6	were	be	AUX
dti-1352	40	7	preceded	precede	VERB
dti-1352	40	8	by	by	ADP
dti-1352	40	9	behavioral	behavioral	ADJ
dti-1352	40	10	assays	assay	NOUN
dti-1352	40	11	to	to	PART
dti-1352	40	12	investigate	investigate	VERB
dti-1352	40	13	the	the	DET
dti-1352	40	14	antidepressant	antidepressant	ADJ
dti-1352	40	15	activity	activity	NOUN
dti-1352	40	16	of	of	ADP
dti-1352	40	17	agomelatine	agomelatine	NOUN
dti-1352	40	18	via	via	ADP
dti-1352	40	19	the	the	DET
dti-1352	40	20	forced	force	VERB
dti-1352	40	21	swimming	swimming	NOUN
dti-1352	40	22	test21	test21	NOUN
dti-1352	40	23	and	and	CCONJ
dti-1352	40	24	to	to	PART
dti-1352	40	25	evaluate	evaluate	VERB
dti-1352	40	26	the	the	DET
dti-1352	40	27	effect	effect	NOUN
dti-1352	40	28	of	of	ADP
dti-1352	40	29	agomelatine	agomelatine	NOUN
dti-1352	40	30	on	on	ADP
dti-1352	40	31	recognition	recognition	NOUN
dti-1352	40	32	memory	memory	NOUN
dti-1352	40	33	in	in	ADP
dti-1352	40	34	the	the	DET
dti-1352	40	35	novel	novel	ADJ
dti-1352	40	36	object	object	NOUN
dti-1352	40	37	recognition	recognition	NOUN
dti-1352	40	38	(	(	PUNCT
dti-1352	40	39	nor	nor	CCONJ
dti-1352	40	40	)	)	PUNCT
dti-1352	40	41	task.22	task.22	PROPN
dti-1352	40	42	chronic	chronic	ADJ
dti-1352	40	43	administration	administration	NOUN
dti-1352	40	44	of	of	ADP
dti-1352	40	45	agomelatine	agomelatine	PROPN
dti-1352	40	46	leads	lead	VERB
dti-1352	40	47	to	to	ADP
dti-1352	40	48	the	the	DET
dti-1352	40	49	upregulation	upregulation	NOUN
dti-1352	40	50	of	of	ADP
dti-1352	40	51	bdnf	bdnf	PROPN
dti-1352	40	52	-	-	PUNCT
dti-1352	40	53	ltp	ltp	PROPN
dti-1352	40	54	(	(	PUNCT
dti-1352	40	55	longterm	longterm	ADJ
dti-1352	40	56	potentialization)-related	potentialization)-relate	VERB
dti-1352	40	57	genes	gene	NOUN
dti-1352	40	58	and	and	CCONJ
dti-1352	40	59	reverses	reverse	VERB
dti-1352	40	60	depressionlike	depressionlike	ADJ
dti-1352	40	61	symptoms	symptom	NOUN
dti-1352	40	62	.	.	PUNCT
dti-1352	41	1	creb	creb	NOUN
dti-1352	41	2	is	be	AUX
dti-1352	41	3	a	a	DET
dti-1352	41	4	core	core	NOUN
dti-1352	41	5	component	component	NOUN
dti-1352	41	6	of	of	ADP
dti-1352	41	7	the	the	DET
dti-1352	41	8	molecular	molecular	ADJ
dti-1352	41	9	switch	switch	NOUN
dti-1352	41	10	that	that	PRON
dti-1352	41	11	converts	convert	VERB
dti-1352	41	12	short	short	ADJ
dti-1352	41	13	-	-	PUNCT
dti-1352	41	14	term	term	NOUN
dti-1352	41	15	memory	memory	NOUN
dti-1352	41	16	to	to	ADP
dti-1352	41	17	long	long	ADJ
dti-1352	41	18	-	-	PUNCT
dti-1352	41	19	term	term	NOUN
dti-1352	41	20	memory	memory	NOUN
dti-1352	41	21	.	.	PUNCT
dti-1352	42	1	recent	recent	ADJ
dti-1352	42	2	studies	study	NOUN
dti-1352	42	3	have	have	AUX
dti-1352	42	4	established	establish	VERB
dti-1352	42	5	the	the	DET
dti-1352	42	6	role	role	NOUN
dti-1352	42	7	of	of	ADP
dti-1352	42	8	creb	creb	NOUN
dti-1352	42	9	in	in	ADP
dti-1352	42	10	learning	learning	NOUN
dti-1352	42	11	and	and	CCONJ
dti-1352	42	12	memory	memory	NOUN
dti-1352	42	13	in	in	ADP
dti-1352	42	14	mammals	mammal	NOUN
dti-1352	42	15	in	in	ADP
dti-1352	42	16	addition	addition	NOUN
dti-1352	42	17	to	to	ADP
dti-1352	42	18	providing	provide	VERB
dti-1352	42	19	insight	insight	NOUN
dti-1352	42	20	into	into	ADP
dti-1352	42	21	the	the	DET
dti-1352	42	22	molecular	molecular	ADJ
dti-1352	42	23	mechanisms	mechanism	NOUN
dti-1352	42	24	of	of	ADP
dti-1352	42	25	creb	creb	NOUN
dti-1352	42	26	regulation	regulation	NOUN
dti-1352	42	27	and	and	CCONJ
dti-1352	42	28	function	function	NOUN
dti-1352	42	29	.	.	PUNCT
dti-1352	43	1	the	the	DET
dti-1352	43	2	involvement	involvement	NOUN
dti-1352	43	3	of	of	ADP
dti-1352	43	4	creb	creb	NOUN
dti-1352	43	5	and	and	CCONJ
dti-1352	43	6	the	the	DET
dti-1352	43	7	upstream	upstream	ADJ
dti-1352	43	8	signaling	signal	VERB
dti-1352	43	9	pathways	pathway	NOUN
dti-1352	43	10	leading	lead	VERB
dti-1352	43	11	to	to	ADP
dti-1352	43	12	its	its	PRON
dti-1352	43	13	activation	activation	NOUN
dti-1352	43	14	in	in	ADP
dti-1352	43	15	learningassociated	learningassociate	VERB
dti-1352	43	16	plasticity	plasticity	NOUN
dti-1352	43	17	makes	make	VERB
dti-1352	43	18	them	they	PRON
dti-1352	43	19	attractive	attractive	ADJ
dti-1352	43	20	targets	target	NOUN
dti-1352	43	21	for	for	ADP
dti-1352	43	22	drugs	drug	NOUN
dti-1352	43	23	aimed	aim	VERB
dti-1352	43	24	at	at	ADP
dti-1352	43	25	improving	improve	VERB
dti-1352	43	26	memory	memory	NOUN
dti-1352	43	27	function	function	NOUN
dti-1352	43	28	in	in	ADP
dti-1352	43	29	both	both	CCONJ
dti-1352	43	30	diseased	diseased	ADJ
dti-1352	43	31	and	and	CCONJ
dti-1352	43	32	healthy	healthy	ADJ
dti-1352	43	33	individuals.23	individuals.23	NOUN
dti-1352	43	34	as	as	SCONJ
dti-1352	43	35	stress	stress	NOUN
dti-1352	43	36	plays	play	VERB
dti-1352	43	37	an	an	DET
dti-1352	43	38	important	important	ADJ
dti-1352	43	39	role	role	NOUN
dti-1352	43	40	in	in	ADP
dti-1352	43	41	the	the	DET
dti-1352	43	42	development	development	NOUN
dti-1352	43	43	of	of	ADP
dti-1352	43	44	depression	depression	NOUN
dti-1352	43	45	,	,	PUNCT
dti-1352	43	46	we	we	PRON
dti-1352	43	47	aimed	aim	VERB
dti-1352	43	48	to	to	PART
dti-1352	43	49	investigate	investigate	VERB
dti-1352	43	50	whether	whether	SCONJ
dti-1352	43	51	chronic	chronic	ADJ
dti-1352	43	52	treatment	treatment	NOUN
dti-1352	43	53	with	with	ADP
dti-1352	43	54	agomelatine	agomelatine	NOUN
dti-1352	43	55	,	,	PUNCT
dti-1352	43	56	a	a	DET
dti-1352	43	57	novel	novel	ADJ
dti-1352	43	58	antidepressant	antidepressant	NOUN
dti-1352	43	59	that	that	PRON
dti-1352	43	60	has	have	VERB
dti-1352	43	61	a	a	DET
dti-1352	43	62	unique	unique	ADJ
dti-1352	43	63	receptor	receptor	NOUN
dti-1352	43	64	profile	profile	NOUN
dti-1352	43	65	as	as	ADP
dti-1352	43	66	a	a	DET
dti-1352	43	67	mt1	mt1	PROPN
dti-1352	43	68	/	/	SYM
dti-1352	43	69	mt2	mt2	ADJ
dti-1352	43	70	melatonergic	melatonergic	NOUN
dti-1352	43	71	agonist6	agonist6	NOUN
dti-1352	43	72	and	and	CCONJ
dti-1352	43	73	5	5	NUM
dti-1352	43	74	-	-	PUNCT
dti-1352	43	75	ht2c	ht2c	NOUN
dti-1352	43	76	receptor	receptor	NOUN
dti-1352	43	77	antagonist,7	antagonist,7	NOUN
dti-1352	43	78	would	would	AUX
dti-1352	43	79	block	block	VERB
dti-1352	43	80	ucmsinduced	ucmsinduce	VERB
dti-1352	43	81	cognitive	cognitive	ADJ
dti-1352	43	82	deterioration	deterioration	NOUN
dti-1352	43	83	in	in	ADP
dti-1352	43	84	mice	mouse	NOUN
dti-1352	43	85	in	in	ADP
dti-1352	43	86	the	the	DET
dti-1352	43	87	passive	passive	ADJ
dti-1352	43	88	avoidance	avoidance	NOUN
dti-1352	43	89	(	(	PUNCT
dti-1352	43	90	pa	pa	PROPN
dti-1352	43	91	)	)	PUNCT
dti-1352	43	92	,	,	PUNCT
dti-1352	43	93	modified	modify	VERB
dti-1352	43	94	elevated	elevated	ADJ
dti-1352	43	95	plus	plus	CCONJ
dti-1352	43	96	maze	maze	NOUN
dti-1352	43	97	(	(	PUNCT
dti-1352	43	98	mepm	mepm	NOUN
dti-1352	43	99	)	)	PUNCT
dti-1352	43	100	,	,	PUNCT
dti-1352	43	101	nor	nor	CCONJ
dti-1352	43	102	,	,	PUNCT
dti-1352	43	103	and	and	CCONJ
dti-1352	43	104	morris	morris	PROPN
dti-1352	43	105	water	water	PROPN
dti-1352	43	106	maze	maze	NOUN
dti-1352	43	107	(	(	PUNCT
dti-1352	43	108	mwm	mwm	NOUN
dti-1352	43	109	)	)	PUNCT
dti-1352	43	110	tests	test	NOUN
dti-1352	43	111	.	.	PUNCT
dti-1352	44	1	as	as	SCONJ
dti-1352	44	2	the	the	DET
dti-1352	44	3	genes	gene	NOUN
dti-1352	44	4	involved	involve	VERB
dti-1352	44	5	in	in	ADP
dti-1352	44	6	neurite	neurite	ADJ
dti-1352	44	7	remodeling	remodeling	NOUN
dti-1352	44	8	are	be	AUX
dti-1352	44	9	among	among	ADP
dti-1352	44	10	the	the	DET
dti-1352	44	11	primary	primary	ADJ
dti-1352	44	12	targets	target	NOUN
dti-1352	44	13	of	of	ADP
dti-1352	44	14	regulation	regulation	NOUN
dti-1352	44	15	by	by	ADP
dti-1352	44	16	chronic	chronic	ADJ
dti-1352	44	17	stress	stress	NOUN
dti-1352	44	18	,	,	PUNCT
dti-1352	44	19	the	the	DET
dti-1352	44	20	effects	effect	NOUN
dti-1352	44	21	of	of	ADP
dti-1352	44	22	stress	stress	NOUN
dti-1352	44	23	and	and	CCONJ
dti-1352	44	24	the	the	DET
dti-1352	44	25	chronic	chronic	ADJ
dti-1352	44	26	administration	administration	NOUN
dti-1352	44	27	of	of	ADP
dti-1352	44	28	agomelatine	agomelatine	PROPN
dti-1352	44	29	on	on	ADP
dti-1352	44	30	bdnf	bdnf	PROPN
dti-1352	44	31	and	and	CCONJ
dti-1352	44	32	creb	creb	PROPN
dti-1352	44	33	messenger	messenger	NOUN
dti-1352	44	34	ribonucleic	ribonucleic	ADJ
dti-1352	44	35	acid	acid	PROPN
dti-1352	44	36	(	(	PUNCT
dti-1352	44	37	mrna	mrna	PROPN
dti-1352	44	38	)	)	PUNCT
dti-1352	44	39	expression	expression	NOUN
dti-1352	44	40	in	in	ADP
dti-1352	44	41	the	the	DET
dti-1352	44	42	hippocampus	hippocampus	NOUN
dti-1352	44	43	of	of	ADP
dti-1352	44	44	stressed	stress	VERB
dti-1352	44	45	mice	mouse	NOUN
dti-1352	44	46	were	be	AUX
dti-1352	44	47	also	also	ADV
dti-1352	44	48	determined	determine	VERB
dti-1352	44	49	using	use	VERB
dti-1352	44	50	quantitative	quantitative	ADJ
dti-1352	44	51	realtime	realtime	ADJ
dti-1352	44	52	polymerase	polymerase	NOUN
dti-1352	44	53	chain	chain	NOUN
dti-1352	44	54	reaction	reaction	NOUN
dti-1352	44	55	(	(	PUNCT
dti-1352	44	56	rt	rt	NOUN
dti-1352	44	57	-	-	PUNCT
dti-1352	44	58	pcr	pcr	NOUN
dti-1352	44	59	)	)	PUNCT
dti-1352	44	60	.	.	PUNCT
dti-1352	45	1	methods	method	NOUN
dti-1352	45	2	animals	animal	NOUN
dti-1352	45	3	.	.	PUNCT
dti-1352	46	1	male	male	NOUN
dti-1352	46	2	,	,	PUNCT
dti-1352	46	3	inbred	inbreed	VERB
dti-1352	46	4	balb	balb	ADJ
dti-1352	46	5	/	/	SYM
dti-1352	46	6	cbyj	cbyj	NOUN
dti-1352	46	7	mice	mouse	NOUN
dti-1352	46	8	(	(	PUNCT
dti-1352	46	9	mam	mam	NOUN
dti-1352	46	10	tubi̇tak	tubi̇tak	PROPN
dti-1352	46	11	,	,	PUNCT
dti-1352	46	12	gebze	gebze	NOUN
dti-1352	46	13	,	,	PUNCT
dti-1352	46	14	kocaeli	kocaeli	ADJ
dti-1352	46	15	,	,	PUNCT
dti-1352	46	16	turkey	turkey	PROPN
dti-1352	46	17	)	)	PUNCT
dti-1352	46	18	,	,	PUNCT
dti-1352	46	19	seven	seven	NUM
dti-1352	46	20	to	to	PART
dti-1352	46	21	eight	eight	NUM
dti-1352	46	22	weeks	week	NOUN
dti-1352	46	23	old	old	ADJ
dti-1352	46	24	at	at	ADP
dti-1352	46	25	their	their	PRON
dti-1352	46	26	arrival	arrival	NOUN
dti-1352	46	27	to	to	ADP
dti-1352	46	28	the	the	DET
dti-1352	46	29	laboratory	laboratory	NOUN
dti-1352	46	30	,	,	PUNCT
dti-1352	46	31	were	be	AUX
dti-1352	46	32	used	use	VERB
dti-1352	46	33	in	in	ADP
dti-1352	46	34	this	this	DET
dti-1352	46	35	study	study	NOUN
dti-1352	46	36	.	.	PUNCT
dti-1352	47	1	the	the	DET
dti-1352	47	2	animals	animal	NOUN
dti-1352	47	3	(	(	PUNCT
dti-1352	47	4	four	four	NUM
dti-1352	47	5	to	to	PART
dti-1352	47	6	five	five	NUM
dti-1352	47	7	per	per	ADP
dti-1352	47	8	cage	cage	NOUN
dti-1352	47	9	)	)	PUNCT
dti-1352	47	10	were	be	AUX
dti-1352	47	11	kept	keep	VERB
dti-1352	47	12	in	in	ADP
dti-1352	47	13	the	the	DET
dti-1352	47	14	laboratory	laboratory	NOUN
dti-1352	47	15	at	at	ADP
dti-1352	47	16	21	21	NUM
dti-1352	47	17	±	±	NUM
dti-1352	47	18	1.5	1.5	NUM
dti-1352	47	19	°	°	ADP
dti-1352	47	20	c	c	NOUN
dti-1352	47	21	with	with	ADP
dti-1352	47	22	60	60	NUM
dti-1352	47	23	%	%	NOUN
dti-1352	47	24	relative	relative	ADJ
dti-1352	47	25	humidity	humidity	NOUN
dti-1352	47	26	under	under	ADP
dti-1352	47	27	a	a	DET
dti-1352	47	28	12	12	NUM
dti-1352	47	29	hour	hour	NOUN
dti-1352	47	30	light	light	ADJ
dti-1352	47	31	/	/	SYM
dti-1352	47	32	dark	dark	ADJ
dti-1352	47	33	cycle	cycle	NOUN
dti-1352	47	34	(	(	PUNCT
dti-1352	47	35	lights	light	NOUN
dti-1352	47	36	on	on	ADP
dti-1352	47	37	at	at	ADP
dti-1352	47	38	8:00	8:00	NUM
dti-1352	47	39	p.m.	p.m.	NOUN
dti-1352	47	40	)	)	PUNCT
dti-1352	47	41	for	for	ADP
dti-1352	47	42	two	two	NUM
dti-1352	47	43	weeks	week	NOUN
dti-1352	47	44	before	before	ADP
dti-1352	47	45	experimentation	experimentation	NOUN
dti-1352	47	46	.	.	PUNCT
dti-1352	48	1	the	the	DET
dti-1352	48	2	animals	animal	NOUN
dti-1352	48	3	were	be	AUX
dti-1352	48	4	assigned	assign	VERB
dti-1352	48	5	to	to	ADP
dti-1352	48	6	one	one	NUM
dti-1352	48	7	of	of	ADP
dti-1352	48	8	two	two	NUM
dti-1352	48	9	treatment	treatment	NOUN
dti-1352	48	10	groups	group	NOUN
dti-1352	48	11	,	,	PUNCT
dti-1352	48	12	the	the	DET
dti-1352	48	13	non	non	ADJ
dti-1352	48	14	-	-	ADJ
dti-1352	48	15	stressed	stressed	ADJ
dti-1352	48	16	group	group	NOUN
dti-1352	48	17	(	(	PUNCT
dti-1352	48	18	controls	control	NOUN
dti-1352	48	19	)	)	PUNCT
dti-1352	48	20	and	and	CCONJ
dti-1352	48	21	mice	mouse	NOUN
dti-1352	48	22	subjected	subject	VERB
dti-1352	48	23	to	to	ADP
dti-1352	48	24	the	the	DET
dti-1352	48	25	ucms	ucms	NOUN
dti-1352	48	26	procedure	procedure	NOUN
dti-1352	48	27	.	.	PUNCT
dti-1352	49	1	non	non	ADJ
dti-1352	49	2	-	-	ADJ
dti-1352	49	3	stressed	stressed	ADJ
dti-1352	49	4	mice	mouse	NOUN
dti-1352	49	5	were	be	AUX
dti-1352	49	6	housed	house	VERB
dti-1352	49	7	in	in	ADP
dti-1352	49	8	groups	group	NOUN
dti-1352	49	9	(	(	PUNCT
dti-1352	49	10	eight	eight	NUM
dti-1352	49	11	mice	mouse	NOUN
dti-1352	49	12	per	per	ADP
dti-1352	49	13	cage	cage	NOUN
dti-1352	49	14	)	)	PUNCT
dti-1352	49	15	during	during	ADP
dti-1352	49	16	the	the	DET
dti-1352	49	17	experiment	experiment	NOUN
dti-1352	49	18	,	,	PUNCT
dti-1352	49	19	whereas	whereas	SCONJ
dti-1352	49	20	mice	mouse	NOUN
dti-1352	49	21	in	in	ADP
dti-1352	49	22	the	the	DET
dti-1352	49	23	stressed	stressed	ADJ
dti-1352	49	24	group	group	NOUN
dti-1352	49	25	were	be	AUX
dti-1352	49	26	housed	house	VERB
dti-1352	49	27	individually	individually	ADV
dti-1352	49	28	in	in	ADP
dti-1352	49	29	cages	cage	NOUN
dti-1352	49	30	(	(	PUNCT
dti-1352	49	31	length	length	NOUN
dti-1352	49	32	:	:	PUNCT
dti-1352	49	33	268	268	NUM
dti-1352	49	34	mm	mm	NOUN
dti-1352	49	35	,	,	PUNCT
dti-1352	49	36	width	width	ADJ
dti-1352	49	37	:	:	PUNCT
dti-1352	49	38	135	135	NUM
dti-1352	49	39	mm	mm	NOUN
dti-1352	49	40	,	,	PUNCT
dti-1352	49	41	height	height	NOUN
dti-1352	49	42	:	:	PUNCT
dti-1352	49	43	81	81	NUM
dti-1352	49	44	mm	mm	NOUN
dti-1352	49	45	)	)	PUNCT
dti-1352	49	46	from	from	ADP
dti-1352	49	47	the	the	DET
dti-1352	49	48	start	start	NOUN
dti-1352	49	49	of	of	ADP
dti-1352	49	50	the	the	DET
dti-1352	49	51	chronic	chronic	ADJ
dti-1352	49	52	stress	stress	NOUN
dti-1352	49	53	until	until	ADP
dti-1352	49	54	the	the	DET
dti-1352	49	55	end	end	NOUN
dti-1352	49	56	of	of	ADP
dti-1352	49	57	the	the	DET
dti-1352	49	58	study	study	NOUN
dti-1352	49	59	.	.	PUNCT
dti-1352	50	1	all	all	DET
dti-1352	50	2	animals	animal	NOUN
dti-1352	50	3	received	receive	VERB
dti-1352	50	4	food	food	NOUN
dti-1352	50	5	and	and	CCONJ
dti-1352	50	6	water	water	NOUN
dti-1352	50	7	ad	ad	NOUN
dti-1352	50	8	libitum	libitum	PROPN
dti-1352	50	9	.	.	PUNCT
dti-1352	51	1	a	a	DET
dti-1352	51	2	grouphoused	grouphouse	VERB
dti-1352	51	3	control	control	NOUN
dti-1352	51	4	group	group	NOUN
dti-1352	51	5	was	be	AUX
dti-1352	51	6	preferred	prefer	VERB
dti-1352	51	7	to	to	ADP
dti-1352	51	8	an	an	DET
dti-1352	51	9	individual	individual	ADJ
dti-1352	51	10	-	-	PUNCT
dti-1352	51	11	housing	housing	NOUN
dti-1352	51	12	condition	condition	NOUN
dti-1352	51	13	because	because	SCONJ
dti-1352	51	14	social	social	ADJ
dti-1352	51	15	isolation	isolation	NOUN
dti-1352	51	16	is	be	AUX
dti-1352	51	17	highly	highly	ADV
dti-1352	51	18	stressful	stressful	ADJ
dti-1352	51	19	for	for	ADP
dti-1352	51	20	mice	mouse	NOUN
dti-1352	51	21	and	and	CCONJ
dti-1352	51	22	should	should	AUX
dti-1352	51	23	thus	thus	ADV
dti-1352	51	24	per	per	X
dti-1352	51	25	se	se	X
dti-1352	51	26	contribute	contribute	VERB
dti-1352	51	27	to	to	ADP
dti-1352	51	28	the	the	DET
dti-1352	51	29	effects	effect	NOUN
dti-1352	51	30	of	of	ADP
dti-1352	51	31	chronic	chronic	ADJ
dti-1352	51	32	stress.24,25	stress.24,25	VERB
dti-1352	51	33	all	all	DET
dti-1352	51	34	procedures	procedure	NOUN
dti-1352	51	35	described	describe	VERB
dti-1352	51	36	in	in	ADP
dti-1352	51	37	this	this	DET
dti-1352	51	38	paper	paper	NOUN
dti-1352	51	39	were	be	AUX
dti-1352	51	40	conducted	conduct	VERB
dti-1352	51	41	in	in	ADP
dti-1352	51	42	accordance	accordance	NOUN
dti-1352	51	43	with	with	ADP
dti-1352	51	44	the	the	DET
dti-1352	51	45	european	european	PROPN
dti-1352	51	46	community	community	PROPN
dti-1352	51	47	council	council	NOUN
dti-1352	51	48	directive	directive	NOUN
dti-1352	51	49	for	for	ADP
dti-1352	51	50	the	the	DET
dti-1352	51	51	ethical	ethical	ADJ
dti-1352	51	52	treatment	treatment	NOUN
dti-1352	51	53	of	of	ADP
dti-1352	51	54	animals	animal	NOUN
dti-1352	51	55	(	(	PUNCT
dti-1352	51	56	86/609	86/609	NUM
dti-1352	51	57	/	/	SYM
dti-1352	51	58	eec	eec	PROPN
dti-1352	51	59	)	)	PUNCT
dti-1352	51	60	and	and	CCONJ
dti-1352	51	61	with	with	ADP
dti-1352	51	62	the	the	DET
dti-1352	51	63	ethical	ethical	ADJ
dti-1352	51	64	approval	approval	NOUN
dti-1352	51	65	of	of	ADP
dti-1352	51	66	the	the	DET
dti-1352	51	67	kocaeli	kocaeli	PROPN
dti-1352	51	68	university	university	PROPN
dti-1352	51	69	ethics	ethic	NOUN
dti-1352	51	70	committee	committee	PROPN
dti-1352	51	71	(	(	PUNCT
dti-1352	51	72	number	number	NOUN
dti-1352	51	73	:	:	PUNCT
dti-1352	51	74	aek	aek	PROPN
dti-1352	51	75	9/3	9/3	NUM
dti-1352	51	76	2010	2010	NUM
dti-1352	51	77	,	,	PUNCT
dti-1352	51	78	kocaeli	kocaeli	ADJ
dti-1352	51	79	,	,	PUNCT
dti-1352	51	80	turkey	turkey	PROPN
dti-1352	51	81	)	)	PUNCT
dti-1352	51	82	.	.	PUNCT
dti-1352	52	1	http://www.la-press.com	http://www.la-press.com	X
dti-1352	52	2	agomelatin	agomelatin	PROPN
dti-1352	52	3	improves	improve	VERB
dti-1352	52	4	memory	memory	NOUN
dti-1352	52	5	in	in	ADP
dti-1352	52	6	stress	stress	NOUN
dti-1352	52	7	exposed	expose	VERB
dti-1352	52	8	mice	mouse	NOUN
dti-1352	52	9	13drug	13drug	PUNCT
dti-1352	53	1	target	target	NOUN
dti-1352	53	2	insights	insight	NOUN
dti-1352	53	3	2014:8	2014:8	NUM
dti-1352	53	4	all	all	DET
dti-1352	53	5	animals	animal	NOUN
dti-1352	53	6	were	be	AUX
dti-1352	53	7	naive	naive	ADJ
dti-1352	53	8	to	to	ADP
dti-1352	53	9	the	the	DET
dti-1352	53	10	experimental	experimental	ADJ
dti-1352	53	11	apparatus	apparatus	NOUN
dti-1352	53	12	,	,	PUNCT
dti-1352	53	13	and	and	CCONJ
dti-1352	53	14	different	different	ADJ
dti-1352	53	15	animals	animal	NOUN
dti-1352	53	16	were	be	AUX
dti-1352	53	17	used	use	VERB
dti-1352	53	18	for	for	ADP
dti-1352	53	19	each	each	DET
dti-1352	53	20	test	test	NOUN
dti-1352	53	21	.	.	PUNCT
dti-1352	54	1	experimental	experimental	ADJ
dti-1352	54	2	groups	group	NOUN
dti-1352	54	3	and	and	CCONJ
dti-1352	54	4	drug	drug	NOUN
dti-1352	54	5	administration	administration	NOUN
dti-1352	54	6	.	.	PUNCT
dti-1352	55	1	melatonin	melatonin	PROPN
dti-1352	55	2	was	be	AUX
dti-1352	55	3	purchased	purchase	VERB
dti-1352	55	4	from	from	ADP
dti-1352	55	5	merck	merck	PROPN
dti-1352	55	6	chemical	chemical	PROPN
dti-1352	55	7	company	company	NOUN
dti-1352	55	8	(	(	PUNCT
dti-1352	55	9	merck	merck	PROPN
dti-1352	55	10	,	,	PUNCT
dti-1352	55	11	hohenbrunn	hohenbrunn	PROPN
dti-1352	55	12	,	,	PUNCT
dti-1352	55	13	germany	germany	PROPN
dti-1352	55	14	)	)	PUNCT
dti-1352	55	15	,	,	PUNCT
dti-1352	55	16	and	and	CCONJ
dti-1352	55	17	agomelatine	agomelatine	PROPN
dti-1352	55	18	was	be	AUX
dti-1352	55	19	purchased	purchase	VERB
dti-1352	55	20	from	from	ADP
dti-1352	55	21	wuhan	wuhan	PROPN
dti-1352	55	22	sunrise	sunrise	PROPN
dti-1352	55	23	technology	technology	PROPN
dti-1352	55	24	development	development	NOUN
dti-1352	55	25	company	company	NOUN
dti-1352	55	26	limited	limit	VERB
dti-1352	55	27	(	(	PUNCT
dti-1352	55	28	wuhan	wuhan	PROPN
dti-1352	55	29	,	,	PUNCT
dti-1352	55	30	china	china	PROPN
dti-1352	55	31	)	)	PUNCT
dti-1352	55	32	.	.	PUNCT
dti-1352	56	1	both	both	PRON
dti-1352	56	2	were	be	AUX
dti-1352	56	3	dissolved	dissolve	VERB
dti-1352	56	4	in	in	ADP
dti-1352	56	5	saline	saline	NOUN
dti-1352	56	6	supplemented	supplement	VERB
dti-1352	56	7	with	with	ADP
dti-1352	56	8	10	10	NUM
dti-1352	56	9	%	%	NOUN
dti-1352	56	10	dmso	dmso	NOUN
dti-1352	56	11	.	.	PUNCT
dti-1352	57	1	all	all	DET
dti-1352	57	2	drugs	drug	NOUN
dti-1352	57	3	were	be	AUX
dti-1352	57	4	freshly	freshly	ADV
dti-1352	57	5	prepared	prepare	VERB
dti-1352	57	6	and	and	CCONJ
dti-1352	57	7	administered	administer	VERB
dti-1352	57	8	in	in	ADP
dti-1352	57	9	a	a	DET
dti-1352	57	10	volume	volume	NOUN
dti-1352	57	11	of	of	ADP
dti-1352	57	12	0.1	0.1	NUM
dti-1352	57	13	ml	ml	NOUN
dti-1352	57	14	per	per	ADP
dti-1352	57	15	10	10	NUM
dti-1352	57	16	g	g	NOUN
dti-1352	57	17	body	body	NOUN
dti-1352	57	18	weight	weight	NOUN
dti-1352	57	19	.	.	PUNCT
dti-1352	58	1	the	the	DET
dti-1352	58	2	control	control	NOUN
dti-1352	58	3	groups	group	NOUN
dti-1352	58	4	received	receive	VERB
dti-1352	58	5	the	the	DET
dti-1352	58	6	same	same	ADJ
dti-1352	58	7	volume	volume	NOUN
dti-1352	58	8	of	of	ADP
dti-1352	58	9	vehicle	vehicle	NOUN
dti-1352	58	10	.	.	PUNCT
dti-1352	59	1	at	at	ADP
dti-1352	59	2	the	the	DET
dti-1352	59	3	end	end	NOUN
dti-1352	59	4	of	of	ADP
dti-1352	59	5	two	two	NUM
dti-1352	59	6	weeks	week	NOUN
dti-1352	59	7	of	of	ADP
dti-1352	59	8	drug	drug	NOUN
dti-1352	59	9	-	-	PUNCT
dti-1352	59	10	free	free	ADJ
dti-1352	59	11	ucms	ucms	NOUN
dti-1352	59	12	,	,	PUNCT
dti-1352	59	13	the	the	DET
dti-1352	59	14	mice	mouse	NOUN
dti-1352	59	15	were	be	AUX
dti-1352	59	16	assigned	assign	VERB
dti-1352	59	17	to	to	ADP
dti-1352	59	18	six	six	NUM
dti-1352	59	19	experimental	experimental	ADJ
dti-1352	59	20	groups	group	NOUN
dti-1352	59	21	(	(	PUNCT
dti-1352	59	22	n	n	NOUN
dti-1352	59	23	=	=	SYM
dti-1352	59	24	15	15	NUM
dti-1352	59	25	per	per	ADP
dti-1352	59	26	group	group	NOUN
dti-1352	59	27	)	)	PUNCT
dti-1352	59	28	in	in	ADP
dti-1352	59	29	a	a	DET
dti-1352	59	30	semi	semi	ADJ
dti-1352	59	31	-	-	ADJ
dti-1352	59	32	randomized	randomized	ADJ
dti-1352	59	33	manner	manner	NOUN
dti-1352	59	34	such	such	ADJ
dti-1352	59	35	that	that	SCONJ
dti-1352	59	36	the	the	DET
dti-1352	59	37	initial	initial	ADJ
dti-1352	59	38	coat	coat	NOUN
dti-1352	59	39	state	state	NOUN
dti-1352	59	40	and	and	CCONJ
dti-1352	59	41	body	body	NOUN
dti-1352	59	42	weights	weight	NOUN
dti-1352	59	43	were	be	AUX
dti-1352	59	44	equivalent	equivalent	ADJ
dti-1352	59	45	in	in	ADP
dti-1352	59	46	all	all	PRON
dti-1352	59	47	of	of	ADP
dti-1352	59	48	the	the	DET
dti-1352	59	49	groups	group	NOUN
dti-1352	59	50	.	.	PUNCT
dti-1352	60	1	melatonin	melatonin	NOUN
dti-1352	60	2	(	(	PUNCT
dti-1352	60	3	10	10	NUM
dti-1352	60	4	mg	mg	NUM
dti-1352	60	5	/	/	SYM
dti-1352	60	6	kg	kg	PROPN
dti-1352	60	7	)	)	PUNCT
dti-1352	60	8	,	,	PUNCT
dti-1352	60	9	agomelatine	agomelatine	NOUN
dti-1352	60	10	(	(	PUNCT
dti-1352	60	11	10	10	NUM
dti-1352	60	12	mg	mg	NUM
dti-1352	60	13	/	/	SYM
dti-1352	60	14	kg	kg	NOUN
dti-1352	60	15	)	)	PUNCT
dti-1352	60	16	,	,	PUNCT
dti-1352	60	17	or	or	CCONJ
dti-1352	60	18	vehicle	vehicle	NOUN
dti-1352	60	19	was	be	AUX
dti-1352	60	20	administered	administer	VERB
dti-1352	60	21	intraperitoneally	intraperitoneally	ADV
dti-1352	60	22	(	(	PUNCT
dti-1352	60	23	i.p	i.p	PROPN
dti-1352	60	24	.	.	PROPN
dti-1352	60	25	)	)	PUNCT
dti-1352	61	1	each	each	DET
dti-1352	61	2	day	day	NOUN
dti-1352	61	3	at	at	ADP
dti-1352	61	4	17:00	17:00	NUM
dti-1352	61	5	hours	hour	NOUN
dti-1352	61	6	(	(	PUNCT
dti-1352	61	7	two	two	NUM
dti-1352	61	8	hours	hour	NOUN
dti-1352	61	9	before	before	SCONJ
dti-1352	61	10	the	the	DET
dti-1352	61	11	lights	light	NOUN
dti-1352	61	12	were	be	AUX
dti-1352	61	13	turned	turn	VERB
dti-1352	61	14	off	off	ADP
dti-1352	61	15	)	)	PUNCT
dti-1352	61	16	for	for	ADP
dti-1352	61	17	five	five	NUM
dti-1352	61	18	weeks	week	NOUN
dti-1352	61	19	to	to	AUX
dti-1352	61	20	both	both	CCONJ
dti-1352	61	21	stressed	stress	VERB
dti-1352	61	22	and	and	CCONJ
dti-1352	61	23	non	non	ADJ
dti-1352	61	24	-	-	ADJ
dti-1352	61	25	stressed	stressed	ADJ
dti-1352	61	26	animals	animal	NOUN
dti-1352	61	27	.	.	PUNCT
dti-1352	62	1	on	on	ADP
dti-1352	62	2	the	the	DET
dti-1352	62	3	final	final	ADJ
dti-1352	62	4	day	day	NOUN
dti-1352	62	5	of	of	ADP
dti-1352	62	6	injections	injection	NOUN
dti-1352	62	7	(	(	PUNCT
dti-1352	62	8	day	day	NOUN
dti-1352	62	9	35	35	NUM
dti-1352	62	10	)	)	PUNCT
dti-1352	62	11	,	,	PUNCT
dti-1352	62	12	agomelatine-	agomelatine-	ADJ
dti-1352	62	13	,	,	PUNCT
dti-1352	62	14	melatonin-	melatonin-	X
dti-1352	62	15	,	,	PUNCT
dti-1352	62	16	or	or	CCONJ
dti-1352	62	17	vehicle	vehicle	NOUN
dti-1352	62	18	-	-	PUNCT
dti-1352	62	19	treated	treat	VERB
dti-1352	62	20	mice	mouse	NOUN
dti-1352	62	21	(	(	PUNCT
dti-1352	62	22	n	n	NOUN
dti-1352	62	23	=	=	SYM
dti-1352	62	24	7	7	NUM
dti-1352	62	25	per	per	ADP
dti-1352	62	26	group	group	NOUN
dti-1352	62	27	)	)	PUNCT
dti-1352	62	28	were	be	AUX
dti-1352	62	29	sacrificed	sacrifice	VERB
dti-1352	62	30	without	without	ADP
dti-1352	62	31	behavioral	behavioral	ADJ
dti-1352	62	32	testing	testing	NOUN
dti-1352	62	33	to	to	PART
dti-1352	62	34	examine	examine	VERB
dti-1352	62	35	the	the	DET
dti-1352	62	36	effects	effect	NOUN
dti-1352	62	37	of	of	ADP
dti-1352	62	38	the	the	DET
dti-1352	62	39	drugs	drug	NOUN
dti-1352	62	40	on	on	ADP
dti-1352	62	41	the	the	DET
dti-1352	62	42	gene	gene	NOUN
dti-1352	62	43	expression	expression	NOUN
dti-1352	62	44	levels	level	NOUN
dti-1352	62	45	of	of	ADP
dti-1352	62	46	bdnf	bdnf	PROPN
dti-1352	62	47	and	and	CCONJ
dti-1352	62	48	creb	creb	NOUN
dti-1352	62	49	.	.	PUNCT
dti-1352	63	1	the	the	DET
dti-1352	63	2	remaining	remain	VERB
dti-1352	63	3	animals	animal	NOUN
dti-1352	63	4	(	(	PUNCT
dti-1352	63	5	n	n	NOUN
dti-1352	63	6	=	=	SYM
dti-1352	63	7	8	8	NUM
dti-1352	63	8	per	per	ADP
dti-1352	63	9	group	group	NOUN
dti-1352	63	10	)	)	PUNCT
dti-1352	63	11	underwent	underwent	NOUN
dti-1352	63	12	training	training	NOUN
dti-1352	63	13	in	in	ADP
dti-1352	63	14	the	the	DET
dti-1352	63	15	elevated	elevated	ADJ
dti-1352	63	16	plus	plus	CCONJ
dti-1352	63	17	maze	maze	NOUN
dti-1352	63	18	,	,	PUNCT
dti-1352	63	19	pa	pa	PROPN
dti-1352	63	20	,	,	PUNCT
dti-1352	63	21	and	and	CCONJ
dti-1352	63	22	mwm	mwm	NOUN
dti-1352	63	23	tests	test	NOUN
dti-1352	63	24	.	.	PUNCT
dti-1352	64	1	all	all	DET
dti-1352	64	2	behavioral	behavioral	ADJ
dti-1352	64	3	testing	testing	NOUN
dti-1352	64	4	and	and	CCONJ
dti-1352	64	5	tissue	tissue	NOUN
dti-1352	64	6	and	and	CCONJ
dti-1352	64	7	blood	blood	NOUN
dti-1352	64	8	sampling	sampling	NOUN
dti-1352	64	9	were	be	AUX
dti-1352	64	10	conducted	conduct	VERB
dti-1352	64	11	two	two	NUM
dti-1352	64	12	to	to	PART
dti-1352	64	13	five	five	NUM
dti-1352	64	14	hours	hour	NOUN
dti-1352	64	15	following	follow	VERB
dti-1352	64	16	the	the	DET
dti-1352	64	17	final	final	ADJ
dti-1352	64	18	injection	injection	NOUN
dti-1352	64	19	,	,	PUNCT
dti-1352	64	20	between	between	ADP
dti-1352	64	21	19:00	19:00	NUM
dti-1352	64	22	and	and	CCONJ
dti-1352	64	23	22:00	22:00	NUM
dti-1352	64	24	hours	hour	NOUN
dti-1352	64	25	.	.	PUNCT
dti-1352	65	1	ucms	ucm	NOUN
dti-1352	65	2	procedure	procedure	NOUN
dti-1352	65	3	.	.	PUNCT
dti-1352	66	1	the	the	DET
dti-1352	66	2	ucms	ucms	NOUN
dti-1352	66	3	regimen	regiman	NOUN
dti-1352	66	4	used	use	VERB
dti-1352	66	5	in	in	ADP
dti-1352	66	6	this	this	DET
dti-1352	66	7	study	study	NOUN
dti-1352	66	8	was	be	AUX
dti-1352	66	9	based	base	VERB
dti-1352	66	10	on	on	ADP
dti-1352	66	11	the	the	DET
dti-1352	66	12	procedure	procedure	NOUN
dti-1352	66	13	originally	originally	ADV
dti-1352	66	14	designed	design	VERB
dti-1352	66	15	by	by	ADP
dti-1352	66	16	willner	willn	ADJ
dti-1352	66	17	et	et	NOUN
dti-1352	66	18	al.26	al.26	NOUN
dti-1352	66	19	and	and	CCONJ
dti-1352	66	20	adapted	adapt	VERB
dti-1352	66	21	to	to	PART
dti-1352	66	22	mice.27	mice.27	VERB
dti-1352	66	23	this	this	DET
dti-1352	66	24	stress	stress	NOUN
dti-1352	66	25	model	model	NOUN
dti-1352	66	26	consists	consist	VERB
dti-1352	66	27	of	of	ADP
dti-1352	66	28	repeated	repeat	VERB
dti-1352	66	29	mild	mild	ADJ
dti-1352	66	30	physical	physical	ADJ
dti-1352	66	31	and	and	CCONJ
dti-1352	66	32	psychological	psychological	ADJ
dti-1352	66	33	stressors	stressor	NOUN
dti-1352	66	34	.	.	PUNCT
dti-1352	67	1	mice	mouse	NOUN
dti-1352	67	2	were	be	AUX
dti-1352	67	3	subjected	subject	VERB
dti-1352	67	4	to	to	ADP
dti-1352	67	5	different	different	ADJ
dti-1352	67	6	types	type	NOUN
dti-1352	67	7	of	of	ADP
dti-1352	67	8	stressors	stressor	NOUN
dti-1352	67	9	in	in	ADP
dti-1352	67	10	a	a	DET
dti-1352	67	11	chronic	chronic	NOUN
dti-1352	67	12	,	,	PUNCT
dti-1352	67	13	inevitable	inevitable	ADJ
dti-1352	67	14	,	,	PUNCT
dti-1352	67	15	and	and	CCONJ
dti-1352	67	16	unpredictable	unpredictable	ADJ
dti-1352	67	17	way	way	NOUN
dti-1352	67	18	several	several	ADJ
dti-1352	67	19	times	time	NOUN
dti-1352	67	20	a	a	DET
dti-1352	67	21	day	day	NOUN
dti-1352	67	22	for	for	ADP
dti-1352	67	23	seven	seven	NUM
dti-1352	67	24	weeks	week	NOUN
dti-1352	67	25	.	.	PUNCT
dti-1352	68	1	stressors	stressor	NOUN
dti-1352	68	2	were	be	AUX
dti-1352	68	3	administered	administer	VERB
dti-1352	68	4	in	in	ADP
dti-1352	68	5	a	a	DET
dti-1352	68	6	pseudo	pseudo	NOUN
dti-1352	68	7	-	-	ADJ
dti-1352	68	8	random	random	ADJ
dti-1352	68	9	manner	manner	NOUN
dti-1352	68	10	and	and	CCONJ
dti-1352	68	11	could	could	AUX
dti-1352	68	12	occur	occur	VERB
dti-1352	68	13	at	at	ADP
dti-1352	68	14	any	any	DET
dti-1352	68	15	time	time	NOUN
dti-1352	68	16	of	of	ADP
dti-1352	68	17	night	night	NOUN
dti-1352	68	18	or	or	CCONJ
dti-1352	68	19	day	day	NOUN
dti-1352	68	20	.	.	PUNCT
dti-1352	69	1	in	in	ADP
dti-1352	69	2	this	this	DET
dti-1352	69	3	respect	respect	NOUN
dti-1352	69	4	,	,	PUNCT
dti-1352	69	5	the	the	DET
dti-1352	69	6	stressor	stressor	NOUN
dti-1352	69	7	sequence	sequence	NOUN
dti-1352	69	8	was	be	AUX
dti-1352	69	9	changed	change	VERB
dti-1352	69	10	every	every	DET
dti-1352	69	11	week	week	NOUN
dti-1352	69	12	to	to	PART
dti-1352	69	13	make	make	VERB
dti-1352	69	14	the	the	DET
dti-1352	69	15	stress	stress	NOUN
dti-1352	69	16	procedure	procedure	NOUN
dti-1352	69	17	unpredictable	unpredictable	ADJ
dti-1352	69	18	.	.	PUNCT
dti-1352	70	1	in	in	ADP
dti-1352	70	2	all	all	PRON
dti-1352	70	3	of	of	ADP
dti-1352	70	4	the	the	DET
dti-1352	70	5	experiments	experiment	NOUN
dti-1352	70	6	,	,	PUNCT
dti-1352	70	7	the	the	DET
dti-1352	70	8	first	first	ADJ
dti-1352	70	9	two	two	NUM
dti-1352	70	10	drug	drug	NOUN
dti-1352	70	11	-	-	PUNCT
dti-1352	70	12	free	free	ADJ
dti-1352	70	13	weeks	week	NOUN
dti-1352	70	14	of	of	ADP
dti-1352	70	15	ucms	ucm	NOUN
dti-1352	70	16	were	be	AUX
dti-1352	70	17	followed	follow	VERB
dti-1352	70	18	by	by	ADP
dti-1352	70	19	five	five	NUM
dti-1352	70	20	weeks	week	NOUN
dti-1352	70	21	of	of	ADP
dti-1352	70	22	ucms	ucms	NOUN
dti-1352	70	23	application	application	NOUN
dti-1352	70	24	during	during	ADP
dti-1352	70	25	which	which	PRON
dti-1352	70	26	the	the	DET
dti-1352	70	27	mice	mouse	NOUN
dti-1352	70	28	were	be	AUX
dti-1352	70	29	treated	treat	VERB
dti-1352	70	30	with	with	ADP
dti-1352	70	31	drug	drug	NOUN
dti-1352	70	32	or	or	CCONJ
dti-1352	70	33	vehicle	vehicle	NOUN
dti-1352	70	34	.	.	PUNCT
dti-1352	71	1	for	for	ADP
dti-1352	71	2	further	further	ADJ
dti-1352	71	3	details	detail	NOUN
dti-1352	71	4	on	on	ADP
dti-1352	71	5	the	the	DET
dti-1352	71	6	procedure	procedure	NOUN
dti-1352	71	7	,	,	PUNCT
dti-1352	71	8	see	see	VERB
dti-1352	71	9	yalcin	yalcin	PROPN
dti-1352	71	10	et	et	PROPN
dti-1352	71	11	al.28	al.28	PROPN
dti-1352	71	12	pa	pa	PROPN
dti-1352	71	13	test	test	NOUN
dti-1352	71	14	.	.	PUNCT
dti-1352	72	1	animals	animal	NOUN
dti-1352	72	2	were	be	AUX
dti-1352	72	3	trained	train	VERB
dti-1352	72	4	in	in	ADP
dti-1352	72	5	a	a	DET
dti-1352	72	6	one	one	NUM
dti-1352	72	7	-	-	PUNCT
dti-1352	72	8	trial	trial	NOUN
dti-1352	72	9	,	,	PUNCT
dti-1352	72	10	stepthrough	stepthrough	ADJ
dti-1352	72	11	pa	pa	PROPN
dti-1352	72	12	apparatus	apparatus	PROPN
dti-1352	72	13	to	to	PART
dti-1352	72	14	evaluate	evaluate	VERB
dti-1352	72	15	memory	memory	NOUN
dti-1352	72	16	based	base	VERB
dti-1352	72	17	on	on	ADP
dti-1352	72	18	contextual	contextual	ADJ
dti-1352	72	19	fear	fear	NOUN
dti-1352	72	20	conditioning	conditioning	NOUN
dti-1352	72	21	and	and	CCONJ
dti-1352	72	22	instrumental	instrumental	ADJ
dti-1352	72	23	learning.29	learning.29	NOUN
dti-1352	72	24	a	a	DET
dti-1352	72	25	decrease	decrease	NOUN
dti-1352	72	26	in	in	ADP
dti-1352	72	27	retention	retention	NOUN
dti-1352	72	28	latency	latency	NOUN
dti-1352	72	29	indicates	indicate	VERB
dti-1352	72	30	an	an	DET
dti-1352	72	31	impairment	impairment	NOUN
dti-1352	72	32	in	in	ADP
dti-1352	72	33	memory	memory	NOUN
dti-1352	72	34	in	in	ADP
dti-1352	72	35	the	the	DET
dti-1352	72	36	pa	pa	PROPN
dti-1352	72	37	task	task	PROPN
dti-1352	72	38	.	.	PUNCT
dti-1352	73	1	the	the	DET
dti-1352	73	2	apparatus	apparatus	NOUN
dti-1352	73	3	consisted	consist	VERB
dti-1352	73	4	of	of	ADP
dti-1352	73	5	a	a	DET
dti-1352	73	6	box	box	NOUN
dti-1352	73	7	with	with	ADP
dti-1352	73	8	an	an	DET
dti-1352	73	9	illuminated	illuminated	ADJ
dti-1352	73	10	part	part	NOUN
dti-1352	73	11	(	(	PUNCT
dti-1352	73	12	l	l	NOUN
dti-1352	73	13	7	7	NUM
dti-1352	73	14	×	×	PROPN
dti-1352	73	15	12.5	12.5	NUM
dti-1352	73	16	×	×	NOUN
dti-1352	73	17	h	h	NOUN
dti-1352	73	18	14	14	NUM
dti-1352	73	19	cm	cm	NOUN
dti-1352	73	20	)	)	PUNCT
dti-1352	73	21	and	and	CCONJ
dti-1352	73	22	a	a	DET
dti-1352	73	23	dark	dark	ADJ
dti-1352	73	24	part	part	NOUN
dti-1352	73	25	(	(	PUNCT
dti-1352	73	26	l	l	NOUN
dti-1352	73	27	24	24	NUM
dti-1352	73	28	×	×	PROPN
dti-1352	73	29	12.5	12.5	NUM
dti-1352	73	30	×	×	NOUN
dti-1352	73	31	h	h	NOUN
dti-1352	73	32	14	14	NUM
dti-1352	73	33	cm	cm	NOUN
dti-1352	73	34	)	)	PUNCT
dti-1352	73	35	,	,	PUNCT
dti-1352	73	36	both	both	PRON
dti-1352	73	37	equipped	equip	VERB
dti-1352	73	38	with	with	ADP
dti-1352	73	39	a	a	DET
dti-1352	73	40	grid	grid	NOUN
dti-1352	73	41	floor	floor	NOUN
dti-1352	73	42	composed	compose	VERB
dti-1352	73	43	of	of	ADP
dti-1352	73	44	steel	steel	NOUN
dti-1352	73	45	bars	bar	NOUN
dti-1352	73	46	(	(	PUNCT
dti-1352	73	47	0.3	0.3	NUM
dti-1352	73	48	cm	cm	NOUN
dti-1352	73	49	diameter	diameter	NOUN
dti-1352	73	50	)	)	PUNCT
dti-1352	73	51	spaced	space	VERB
dti-1352	73	52	0.9	0.9	NUM
dti-1352	73	53	cm	cm	NOUN
dti-1352	73	54	apart	apart	ADV
dti-1352	73	55	.	.	PUNCT
dti-1352	74	1	the	the	DET
dti-1352	74	2	inhibitory	inhibitory	ADJ
dti-1352	74	3	avoidance	avoidance	NOUN
dti-1352	74	4	task	task	NOUN
dti-1352	74	5	consisted	consist	VERB
dti-1352	74	6	of	of	ADP
dti-1352	74	7	two	two	NUM
dti-1352	74	8	trials	trial	NOUN
dti-1352	74	9	.	.	PUNCT
dti-1352	75	1	on	on	ADP
dti-1352	75	2	the	the	DET
dti-1352	75	3	first	first	ADJ
dti-1352	75	4	day	day	NOUN
dti-1352	75	5	of	of	ADP
dti-1352	75	6	training	training	NOUN
dti-1352	75	7	,	,	PUNCT
dti-1352	75	8	the	the	DET
dti-1352	75	9	mice	mouse	NOUN
dti-1352	75	10	were	be	AUX
dti-1352	75	11	individually	individually	ADV
dti-1352	75	12	placed	place	VERB
dti-1352	75	13	into	into	ADP
dti-1352	75	14	the	the	DET
dti-1352	75	15	light	light	ADJ
dti-1352	75	16	compartment	compartment	NOUN
dti-1352	75	17	and	and	CCONJ
dti-1352	75	18	allowed	allow	VERB
dti-1352	75	19	to	to	PART
dti-1352	75	20	explore	explore	VERB
dti-1352	75	21	the	the	DET
dti-1352	75	22	boxes	box	NOUN
dti-1352	75	23	.	.	PUNCT
dti-1352	76	1	the	the	DET
dti-1352	76	2	intercompartment	intercompartment	NOUN
dti-1352	76	3	door	door	NOUN
dti-1352	76	4	was	be	AUX
dti-1352	76	5	opened	open	VERB
dti-1352	76	6	after	after	ADP
dti-1352	76	7	a	a	DET
dti-1352	76	8	60	60	NUM
dti-1352	76	9	second	second	ADJ
dti-1352	76	10	acclimation	acclimation	NOUN
dti-1352	76	11	period	period	NOUN
dti-1352	76	12	.	.	PUNCT
dti-1352	77	1	in	in	ADP
dti-1352	77	2	the	the	DET
dti-1352	77	3	acquisition	acquisition	NOUN
dti-1352	77	4	trial	trial	NOUN
dti-1352	77	5	,	,	PUNCT
dti-1352	77	6	each	each	DET
dti-1352	77	7	mouse	mouse	NOUN
dti-1352	77	8	was	be	AUX
dti-1352	77	9	placed	place	VERB
dti-1352	77	10	in	in	ADP
dti-1352	77	11	the	the	DET
dti-1352	77	12	illuminated	illuminated	ADJ
dti-1352	77	13	compartment	compartment	NOUN
dti-1352	77	14	,	,	PUNCT
dti-1352	77	15	which	which	PRON
dti-1352	77	16	was	be	AUX
dti-1352	77	17	lit	light	VERB
dti-1352	77	18	by	by	ADP
dti-1352	77	19	a	a	DET
dti-1352	77	20	bright	bright	ADJ
dti-1352	77	21	bulb	bulb	NOUN
dti-1352	77	22	(	(	PUNCT
dti-1352	77	23	2000	2000	NUM
dti-1352	77	24	lux	lux	NOUN
dti-1352	77	25	)	)	PUNCT
dti-1352	77	26	.	.	PUNCT
dti-1352	78	1	the	the	DET
dti-1352	78	2	animals	animal	NOUN
dti-1352	78	3	received	receive	VERB
dti-1352	78	4	drugs	drug	NOUN
dti-1352	78	5	prior	prior	ADV
dti-1352	78	6	to	to	ADP
dti-1352	78	7	acquisition	acquisition	NOUN
dti-1352	78	8	training	training	NOUN
dti-1352	78	9	.	.	PUNCT
dti-1352	79	1	if	if	SCONJ
dti-1352	79	2	the	the	DET
dti-1352	79	3	mouse	mouse	NOUN
dti-1352	79	4	stepped	step	VERB
dti-1352	79	5	into	into	ADP
dti-1352	79	6	the	the	DET
dti-1352	79	7	dark	dark	ADJ
dti-1352	79	8	compartment	compartment	NOUN
dti-1352	79	9	(	(	PUNCT
dti-1352	79	10	2/3	2/3	NUM
dti-1352	79	11	of	of	ADP
dti-1352	79	12	the	the	DET
dti-1352	79	13	tail	tail	NOUN
dti-1352	79	14	in	in	ADP
dti-1352	79	15	the	the	DET
dti-1352	79	16	dark	dark	ADJ
dti-1352	79	17	compartment	compartment	NOUN
dti-1352	79	18	)	)	PUNCT
dti-1352	79	19	,	,	PUNCT
dti-1352	79	20	the	the	DET
dti-1352	79	21	door	door	NOUN
dti-1352	79	22	was	be	AUX
dti-1352	79	23	closed	close	VERB
dti-1352	79	24	by	by	ADP
dti-1352	79	25	the	the	DET
dti-1352	79	26	experimenter	experimenter	NOUN
dti-1352	79	27	,	,	PUNCT
dti-1352	79	28	and	and	CCONJ
dti-1352	79	29	an	an	DET
dti-1352	79	30	inescapable	inescapable	ADJ
dti-1352	79	31	foot	foot	NOUN
dti-1352	79	32	shock	shock	NOUN
dti-1352	79	33	(	(	PUNCT
dti-1352	79	34	0.25	0.25	NUM
dti-1352	79	35	ma/1	ma/1	NOUN
dti-1352	79	36	second	second	ADJ
dti-1352	79	37	)	)	PUNCT
dti-1352	79	38	was	be	AUX
dti-1352	79	39	delivered	deliver	VERB
dti-1352	79	40	through	through	ADP
dti-1352	79	41	the	the	DET
dti-1352	79	42	grid	grid	NOUN
dti-1352	79	43	floor	floor	NOUN
dti-1352	79	44	of	of	ADP
dti-1352	79	45	the	the	DET
dti-1352	79	46	dark	dark	ADJ
dti-1352	79	47	compartment	compartment	NOUN
dti-1352	79	48	.	.	PUNCT
dti-1352	80	1	a	a	DET
dti-1352	80	2	cutoff	cutoff	NOUN
dti-1352	80	3	time	time	NOUN
dti-1352	80	4	of	of	ADP
dti-1352	80	5	five	five	NUM
dti-1352	80	6	minutes	minute	NOUN
dti-1352	80	7	was	be	AUX
dti-1352	80	8	selected	select	VERB
dti-1352	80	9	.	.	PUNCT
dti-1352	81	1	the	the	DET
dti-1352	81	2	time	time	NOUN
dti-1352	81	3	taken	take	VERB
dti-1352	81	4	to	to	PART
dti-1352	81	5	enter	enter	VERB
dti-1352	81	6	the	the	DET
dti-1352	81	7	dark	dark	ADJ
dti-1352	81	8	compartment	compartment	NOUN
dti-1352	81	9	(	(	PUNCT
dti-1352	81	10	training	training	NOUN
dti-1352	81	11	latency	latency	NOUN
dti-1352	81	12	)	)	PUNCT
dti-1352	81	13	was	be	AUX
dti-1352	81	14	recorded	record	VERB
dti-1352	81	15	.	.	PUNCT
dti-1352	82	1	immediately	immediately	ADV
dti-1352	82	2	after	after	ADP
dti-1352	82	3	the	the	DET
dti-1352	82	4	shock	shock	NOUN
dti-1352	82	5	,	,	PUNCT
dti-1352	82	6	the	the	DET
dti-1352	82	7	mouse	mouse	NOUN
dti-1352	82	8	was	be	AUX
dti-1352	82	9	returned	return	VERB
dti-1352	82	10	to	to	ADP
dti-1352	82	11	the	the	DET
dti-1352	82	12	home	home	NOUN
dti-1352	82	13	cage	cage	NOUN
dti-1352	82	14	.	.	PUNCT
dti-1352	83	1	the	the	DET
dti-1352	83	2	retention	retention	NOUN
dti-1352	83	3	trial	trial	NOUN
dti-1352	83	4	started	start	VERB
dti-1352	83	5	24	24	NUM
dti-1352	83	6	hours	hour	NOUN
dti-1352	83	7	after	after	ADP
dti-1352	83	8	the	the	DET
dti-1352	83	9	end	end	NOUN
dti-1352	83	10	of	of	ADP
dti-1352	83	11	the	the	DET
dti-1352	83	12	acquisition	acquisition	NOUN
dti-1352	83	13	trial	trial	NOUN
dti-1352	83	14	.	.	PUNCT
dti-1352	84	1	each	each	DET
dti-1352	84	2	mouse	mouse	NOUN
dti-1352	84	3	was	be	AUX
dti-1352	84	4	placed	place	VERB
dti-1352	84	5	in	in	ADP
dti-1352	84	6	the	the	DET
dti-1352	84	7	illuminated	illuminated	ADJ
dti-1352	84	8	compartment	compartment	NOUN
dti-1352	84	9	as	as	ADP
dti-1352	84	10	in	in	ADP
dti-1352	84	11	the	the	DET
dti-1352	84	12	training	training	NOUN
dti-1352	84	13	trial	trial	NOUN
dti-1352	84	14	.	.	PUNCT
dti-1352	85	1	the	the	DET
dti-1352	85	2	door	door	NOUN
dti-1352	85	3	was	be	AUX
dti-1352	85	4	opened	open	VERB
dti-1352	85	5	after	after	ADP
dti-1352	85	6	a	a	DET
dti-1352	85	7	30	30	NUM
dti-1352	85	8	second	second	ADJ
dti-1352	85	9	acclimation	acclimation	NOUN
dti-1352	85	10	period	period	NOUN
dti-1352	85	11	.	.	PUNCT
dti-1352	86	1	the	the	DET
dti-1352	86	2	step	step	NOUN
dti-1352	86	3	-	-	PUNCT
dti-1352	86	4	through	through	ADP
dti-1352	86	5	latency	latency	NOUN
dti-1352	86	6	in	in	ADP
dti-1352	86	7	the	the	DET
dti-1352	86	8	retention	retention	NOUN
dti-1352	86	9	trial	trial	NOUN
dti-1352	86	10	(	(	PUNCT
dti-1352	86	11	with	with	ADP
dti-1352	86	12	a	a	DET
dti-1352	86	13	maximum	maximum	ADJ
dti-1352	86	14	300	300	NUM
dti-1352	86	15	seconds	second	NOUN
dti-1352	86	16	cutoff	cutoff	NOUN
dti-1352	86	17	time	time	NOUN
dti-1352	86	18	)	)	PUNCT
dti-1352	86	19	was	be	AUX
dti-1352	86	20	used	use	VERB
dti-1352	86	21	as	as	ADP
dti-1352	86	22	the	the	DET
dti-1352	86	23	index	index	NOUN
dti-1352	86	24	of	of	ADP
dti-1352	86	25	retention	retention	NOUN
dti-1352	86	26	of	of	ADP
dti-1352	86	27	the	the	DET
dti-1352	86	28	learned	learn	VERB
dti-1352	86	29	experience	experience	NOUN
dti-1352	86	30	.	.	PUNCT
dti-1352	87	1	a	a	DET
dti-1352	87	2	shock	shock	NOUN
dti-1352	87	3	was	be	AUX
dti-1352	87	4	not	not	PART
dti-1352	87	5	applied	apply	VERB
dti-1352	87	6	during	during	ADP
dti-1352	87	7	the	the	DET
dti-1352	87	8	retention	retention	NOUN
dti-1352	87	9	trial	trial	NOUN
dti-1352	87	10	.	.	PUNCT
dti-1352	88	1	mepm	mepm	PROPN
dti-1352	88	2	test	test	NOUN
dti-1352	88	3	.	.	PUNCT
dti-1352	89	1	cognitive	cognitive	ADJ
dti-1352	89	2	behavior	behavior	NOUN
dti-1352	89	3	was	be	AUX
dti-1352	89	4	evaluated	evaluate	VERB
dti-1352	89	5	using	use	VERB
dti-1352	89	6	the	the	DET
dti-1352	89	7	mepm	mepm	NOUN
dti-1352	89	8	learning	learning	NOUN
dti-1352	89	9	task	task	NOUN
dti-1352	89	10	,	,	PUNCT
dti-1352	89	11	which	which	PRON
dti-1352	89	12	measures	measure	VERB
dti-1352	89	13	spatial	spatial	ADJ
dti-1352	89	14	long	long	ADJ
dti-1352	89	15	-	-	PUNCT
dti-1352	89	16	term	term	NOUN
dti-1352	89	17	memory.30	memory.30	VERB
dti-1352	89	18	the	the	DET
dti-1352	89	19	maze	maze	NOUN
dti-1352	89	20	was	be	AUX
dti-1352	89	21	made	make	VERB
dti-1352	89	22	of	of	ADP
dti-1352	89	23	wood	wood	NOUN
dti-1352	89	24	and	and	CCONJ
dti-1352	89	25	consisted	consist	VERB
dti-1352	89	26	of	of	ADP
dti-1352	89	27	two	two	NUM
dti-1352	89	28	open	open	ADJ
dti-1352	89	29	arms	arm	NOUN
dti-1352	89	30	(	(	PUNCT
dti-1352	89	31	29	29	NUM
dti-1352	89	32	×	×	NOUN
dti-1352	89	33	5	5	NUM
dti-1352	89	34	cm	cm	NOUN
dti-1352	89	35	)	)	PUNCT
dti-1352	89	36	surrounded	surround	VERB
dti-1352	89	37	by	by	ADP
dti-1352	89	38	a	a	DET
dti-1352	89	39	short	short	ADJ
dti-1352	89	40	(	(	PUNCT
dti-1352	89	41	1	1	NUM
dti-1352	89	42	cm	cm	NOUN
dti-1352	89	43	)	)	PUNCT
dti-1352	89	44	plexiglas	plexigla	NOUN
dti-1352	89	45	edge	edge	VERB
dti-1352	89	46	to	to	PART
dti-1352	89	47	avoid	avoid	VERB
dti-1352	89	48	falls	fall	NOUN
dti-1352	89	49	and	and	CCONJ
dti-1352	89	50	two	two	NUM
dti-1352	89	51	enclosed	enclose	VERB
dti-1352	89	52	arms	arm	NOUN
dti-1352	89	53	(	(	PUNCT
dti-1352	89	54	29	29	NUM
dti-1352	89	55	×	×	NOUN
dti-1352	89	56	5	5	NUM
dti-1352	89	57	×	×	NOUN
dti-1352	89	58	15	15	NUM
dti-1352	89	59	cm	cm	NOUN
dti-1352	89	60	)	)	PUNCT
dti-1352	89	61	arranged	arrange	VERB
dti-1352	89	62	such	such	ADJ
dti-1352	89	63	that	that	SCONJ
dti-1352	89	64	the	the	DET
dti-1352	89	65	two	two	NUM
dti-1352	89	66	open	open	ADJ
dti-1352	89	67	arms	arm	NOUN
dti-1352	89	68	were	be	AUX
dti-1352	89	69	opposite	opposite	ADJ
dti-1352	89	70	to	to	ADP
dti-1352	89	71	each	each	DET
dti-1352	89	72	other	other	ADJ
dti-1352	89	73	.	.	PUNCT
dti-1352	90	1	the	the	DET
dti-1352	90	2	arms	arm	NOUN
dti-1352	90	3	were	be	AUX
dti-1352	90	4	connected	connect	VERB
dti-1352	90	5	by	by	ADP
dti-1352	90	6	a	a	DET
dti-1352	90	7	central	central	ADJ
dti-1352	90	8	platform	platform	NOUN
dti-1352	90	9	(	(	PUNCT
dti-1352	90	10	5	5	NUM
dti-1352	90	11	×	×	NOUN
dti-1352	90	12	5	5	NUM
dti-1352	90	13	cm	cm	NOUN
dti-1352	90	14	)	)	PUNCT
dti-1352	90	15	.	.	PUNCT
dti-1352	91	1	the	the	DET
dti-1352	91	2	maze	maze	NOUN
dti-1352	91	3	was	be	AUX
dti-1352	91	4	elevated	elevate	VERB
dti-1352	91	5	40	40	NUM
dti-1352	91	6	cm	cm	NOUN
dti-1352	91	7	above	above	ADP
dti-1352	91	8	the	the	DET
dti-1352	91	9	floor	floor	NOUN
dti-1352	91	10	.	.	PUNCT
dti-1352	92	1	the	the	DET
dti-1352	92	2	principle	principle	NOUN
dti-1352	92	3	of	of	ADP
dti-1352	92	4	this	this	DET
dti-1352	92	5	experiment	experiment	NOUN
dti-1352	92	6	is	be	AUX
dti-1352	92	7	based	base	VERB
dti-1352	92	8	upon	upon	SCONJ
dti-1352	92	9	the	the	DET
dti-1352	92	10	aversion	aversion	NOUN
dti-1352	92	11	of	of	ADP
dti-1352	92	12	rodents	rodent	NOUN
dti-1352	92	13	to	to	PART
dti-1352	92	14	open	open	VERB
dti-1352	92	15	spaces	space	NOUN
dti-1352	92	16	and	and	CCONJ
dti-1352	92	17	heights	height	NOUN
dti-1352	92	18	.	.	PUNCT
dti-1352	93	1	the	the	DET
dti-1352	93	2	animals	animal	NOUN
dti-1352	93	3	prefer	prefer	VERB
dti-1352	93	4	the	the	DET
dti-1352	93	5	enclosed	enclose	VERB
dti-1352	93	6	,	,	PUNCT
dti-1352	93	7	protected	protect	VERB
dti-1352	93	8	areas	area	NOUN
dti-1352	93	9	of	of	ADP
dti-1352	93	10	the	the	DET
dti-1352	93	11	maze	maze	NOUN
dti-1352	93	12	.	.	PUNCT
dti-1352	94	1	the	the	DET
dti-1352	94	2	procedure	procedure	NOUN
dti-1352	94	3	was	be	AUX
dti-1352	94	4	performed	perform	VERB
dti-1352	94	5	as	as	ADP
dti-1352	94	6	described	describe	VERB
dti-1352	94	7	previously.30,31	previously.30,31	NOUN
dti-1352	94	8	during	during	ADP
dti-1352	94	9	the	the	DET
dti-1352	94	10	acquisition	acquisition	NOUN
dti-1352	94	11	session	session	NOUN
dti-1352	94	12	(	(	PUNCT
dti-1352	94	13	day	day	NOUN
dti-1352	94	14	1	1	NUM
dti-1352	94	15	)	)	PUNCT
dti-1352	94	16	,	,	PUNCT
dti-1352	94	17	each	each	DET
dti-1352	94	18	mouse	mouse	NOUN
dti-1352	94	19	was	be	AUX
dti-1352	94	20	gently	gently	ADV
dti-1352	94	21	placed	place	VERB
dti-1352	94	22	at	at	ADP
dti-1352	94	23	the	the	DET
dti-1352	94	24	distal	distal	ADJ
dti-1352	94	25	end	end	NOUN
dti-1352	94	26	of	of	ADP
dti-1352	94	27	an	an	DET
dti-1352	94	28	open	open	ADJ
dti-1352	94	29	arm	arm	NOUN
dti-1352	94	30	facing	face	VERB
dti-1352	94	31	away	away	ADV
dti-1352	94	32	from	from	ADP
dti-1352	94	33	the	the	DET
dti-1352	94	34	central	central	ADJ
dti-1352	94	35	platform	platform	NOUN
dti-1352	94	36	.	.	PUNCT
dti-1352	95	1	the	the	DET
dti-1352	95	2	time	time	NOUN
dti-1352	95	3	required	require	VERB
dti-1352	95	4	for	for	SCONJ
dti-1352	95	5	the	the	DET
dti-1352	95	6	mice	mouse	NOUN
dti-1352	95	7	to	to	PART
dti-1352	95	8	move	move	VERB
dti-1352	95	9	from	from	ADP
dti-1352	95	10	the	the	DET
dti-1352	95	11	open	open	ADJ
dti-1352	95	12	arm	arm	NOUN
dti-1352	95	13	to	to	ADP
dti-1352	95	14	either	either	PRON
dti-1352	95	15	of	of	ADP
dti-1352	95	16	the	the	DET
dti-1352	95	17	enclosed	enclose	VERB
dti-1352	95	18	arms	arm	NOUN
dti-1352	95	19	(	(	PUNCT
dti-1352	95	20	transfer	transfer	NOUN
dti-1352	95	21	latency	latency	NOUN
dti-1352	95	22	)	)	PUNCT
dti-1352	95	23	was	be	AUX
dti-1352	95	24	recorded	record	VERB
dti-1352	95	25	.	.	PUNCT
dti-1352	96	1	training	training	NOUN
dti-1352	96	2	(	(	PUNCT
dti-1352	96	3	repeated	repeat	VERB
dti-1352	96	4	exposure	exposure	NOUN
dti-1352	96	5	of	of	ADP
dti-1352	96	6	animals	animal	NOUN
dti-1352	96	7	to	to	ADP
dti-1352	96	8	the	the	DET
dti-1352	96	9	open	open	ADJ
dti-1352	96	10	arms	arm	NOUN
dti-1352	96	11	)	)	PUNCT
dti-1352	96	12	shortened	shorten	VERB
dti-1352	96	13	this	this	DET
dti-1352	96	14	parameter	parameter	NOUN
dti-1352	96	15	,	,	PUNCT
dti-1352	96	16	possibly	possibly	ADV
dti-1352	96	17	as	as	ADP
dti-1352	96	18	a	a	DET
dti-1352	96	19	consequence	consequence	NOUN
dti-1352	96	20	of	of	ADP
dti-1352	96	21	learning	learn	VERB
dti-1352	96	22	acquisition	acquisition	NOUN
dti-1352	96	23	and	and	CCONJ
dti-1352	96	24	retention	retention	NOUN
dti-1352	96	25	.	.	PUNCT
dti-1352	97	1	if	if	SCONJ
dti-1352	97	2	the	the	DET
dti-1352	97	3	mouse	mouse	NOUN
dti-1352	97	4	did	do	AUX
dti-1352	97	5	not	not	PART
dti-1352	97	6	enter	enter	VERB
dti-1352	97	7	the	the	DET
dti-1352	97	8	enclosed	enclose	VERB
dti-1352	97	9	arm	arm	NOUN
dti-1352	97	10	within	within	ADP
dti-1352	97	11	90	90	NUM
dti-1352	97	12	seconds	second	NOUN
dti-1352	97	13	,	,	PUNCT
dti-1352	97	14	it	it	PRON
dti-1352	97	15	was	be	AUX
dti-1352	97	16	excluded	exclude	VERB
dti-1352	97	17	from	from	ADP
dti-1352	97	18	further	further	ADJ
dti-1352	97	19	experimentation	experimentation	NOUN
dti-1352	97	20	.	.	PUNCT
dti-1352	98	1	animal	animal	NOUN
dti-1352	98	2	entry	entry	NOUN
dti-1352	98	3	into	into	ADP
dti-1352	98	4	the	the	DET
dti-1352	98	5	enclosed	enclose	VERB
dti-1352	98	6	arm	arm	NOUN
dti-1352	98	7	required	require	VERB
dti-1352	98	8	the	the	DET
dti-1352	98	9	animal	animal	NOUN
dti-1352	98	10	to	to	PART
dti-1352	98	11	cross	cross	VERB
dti-1352	98	12	an	an	DET
dti-1352	98	13	imaginary	imaginary	ADJ
dti-1352	98	14	line	line	NOUN
dti-1352	98	15	separating	separate	VERB
dti-1352	98	16	the	the	DET
dti-1352	98	17	enclosed	enclose	VERB
dti-1352	98	18	arm	arm	NOUN
dti-1352	98	19	from	from	ADP
dti-1352	98	20	the	the	DET
dti-1352	98	21	central	central	ADJ
dti-1352	98	22	space	space	NOUN
dti-1352	98	23	with	with	ADP
dti-1352	98	24	all	all	DET
dti-1352	98	25	four	four	NUM
dti-1352	98	26	legs	leg	NOUN
dti-1352	98	27	.	.	PUNCT
dti-1352	99	1	after	after	ADP
dti-1352	99	2	entering	enter	VERB
dti-1352	99	3	the	the	DET
dti-1352	99	4	enclosed	enclose	VERB
dti-1352	99	5	arm	arm	NOUN
dti-1352	99	6	,	,	PUNCT
dti-1352	99	7	mice	mouse	NOUN
dti-1352	99	8	were	be	AUX
dti-1352	99	9	allowed	allow	VERB
dti-1352	99	10	to	to	PART
dti-1352	99	11	move	move	VERB
dti-1352	99	12	freely	freely	ADV
dti-1352	99	13	in	in	ADP
dti-1352	99	14	the	the	DET
dti-1352	99	15	maze	maze	NOUN
dti-1352	99	16	in	in	ADP
dti-1352	99	17	both	both	CCONJ
dti-1352	99	18	the	the	DET
dti-1352	99	19	open	open	ADJ
dti-1352	99	20	and	and	CCONJ
dti-1352	99	21	enclosed	enclose	VERB
dti-1352	99	22	arms	arm	NOUN
dti-1352	99	23	for	for	ADP
dti-1352	99	24	10	10	NUM
dti-1352	99	25	seconds	second	NOUN
dti-1352	99	26	.	.	PUNCT
dti-1352	100	1	mice	mouse	NOUN
dti-1352	100	2	were	be	AUX
dti-1352	100	3	then	then	ADV
dti-1352	100	4	returned	return	VERB
dti-1352	100	5	to	to	ADP
dti-1352	100	6	their	their	PRON
dti-1352	100	7	home	home	NOUN
dti-1352	100	8	cage	cage	NOUN
dti-1352	100	9	.	.	PUNCT
dti-1352	101	1	the	the	DET
dti-1352	101	2	retention	retention	NOUN
dti-1352	101	3	session	session	NOUN
dti-1352	101	4	occurred	occur	VERB
dti-1352	101	5	24	24	NUM
dti-1352	101	6	hours	hour	NOUN
dti-1352	101	7	after	after	ADP
dti-1352	101	8	the	the	DET
dti-1352	101	9	acquisition	acquisition	NOUN
dti-1352	101	10	session	session	NOUN
dti-1352	101	11	(	(	PUNCT
dti-1352	101	12	on	on	ADP
dti-1352	101	13	day	day	NOUN
dti-1352	101	14	2	2	NUM
dti-1352	101	15	)	)	PUNCT
dti-1352	101	16	.	.	PUNCT
dti-1352	102	1	mice	mouse	NOUN
dti-1352	102	2	were	be	AUX
dti-1352	102	3	placed	place	VERB
dti-1352	102	4	in	in	ADP
dti-1352	102	5	the	the	DET
dti-1352	102	6	open	open	ADJ
dti-1352	102	7	arm	arm	NOUN
dti-1352	102	8	,	,	PUNCT
dti-1352	102	9	and	and	CCONJ
dti-1352	102	10	the	the	DET
dti-1352	102	11	transfer	transfer	NOUN
dti-1352	102	12	latency	latency	NOUN
dti-1352	102	13	was	be	AUX
dti-1352	102	14	recorded	record	VERB
dti-1352	102	15	again	again	ADV
dti-1352	102	16	.	.	PUNCT
dti-1352	103	1	experiments	experiment	NOUN
dti-1352	103	2	were	be	AUX
dti-1352	103	3	conducted	conduct	VERB
dti-1352	103	4	between	between	ADP
dti-1352	103	5	10:00	10:00	NUM
dti-1352	103	6	and	and	CCONJ
dti-1352	103	7	14:00	14:00	NUM
dti-1352	103	8	hours	hour	NOUN
dti-1352	103	9	in	in	ADP
dti-1352	103	10	a	a	DET
dti-1352	103	11	dimly	dimly	ADV
dti-1352	103	12	lit	light	VERB
dti-1352	103	13	,	,	PUNCT
dti-1352	103	14	semisoundproof	semisoundproof	NOUN
dti-1352	103	15	room	room	NOUN
dti-1352	103	16	under	under	ADP
dti-1352	103	17	natural	natural	ADJ
dti-1352	103	18	light	light	NOUN
dti-1352	103	19	.	.	PUNCT
dti-1352	104	1	nor	nor	CCONJ
dti-1352	104	2	.	.	PUNCT
dti-1352	105	1	we	we	PRON
dti-1352	105	2	used	use	VERB
dti-1352	105	3	a	a	DET
dti-1352	105	4	nor	nor	CCONJ
dti-1352	105	5	test	test	NOUN
dti-1352	105	6	protocol	protocol	NOUN
dti-1352	105	7	based	base	VERB
dti-1352	105	8	on	on	ADP
dti-1352	105	9	that	that	PRON
dti-1352	105	10	of	of	ADP
dti-1352	105	11	ennaceur	ennaceur	NOUN
dti-1352	105	12	and	and	CCONJ
dti-1352	105	13	delacour22	delacour22	NOUN
dti-1352	105	14	with	with	ADP
dti-1352	105	15	slight	slight	ADJ
dti-1352	105	16	modifications	modification	NOUN
dti-1352	105	17	.	.	PUNCT
dti-1352	106	1	the	the	DET
dti-1352	106	2	apparatus	apparatus	NOUN
dti-1352	106	3	consisted	consist	VERB
dti-1352	106	4	of	of	ADP
dti-1352	106	5	a	a	DET
dti-1352	106	6	circular	circular	ADJ
dti-1352	106	7	open	open	ADJ
dti-1352	106	8	field	field	NOUN
dti-1352	106	9	(	(	PUNCT
dti-1352	106	10	40	40	NUM
dti-1352	106	11	cm	cm	NOUN
dti-1352	106	12	diameter	diameter	NOUN
dti-1352	106	13	and	and	CCONJ
dti-1352	106	14	30	30	NUM
dti-1352	106	15	cm	cm	NOUN
dti-1352	106	16	height	height	NOUN
dti-1352	106	17	)	)	PUNCT
dti-1352	106	18	made	make	VERB
dti-1352	106	19	of	of	ADP
dti-1352	106	20	pvc	pvc	NOUN
dti-1352	106	21	with	with	ADP
dti-1352	106	22	a	a	DET
dti-1352	106	23	black	black	ADJ
dti-1352	106	24	-	-	PUNCT
dti-1352	106	25	and	and	CCONJ
dti-1352	106	26	-	-	PUNCT
dti-1352	106	27	white	white	ADJ
dti-1352	106	28	striped	striped	ADJ
dti-1352	106	29	cardboard	cardboard	NOUN
dti-1352	106	30	pattern	pattern	NOUN
dti-1352	106	31	(	(	PUNCT
dti-1352	106	32	30	30	NUM
dti-1352	106	33	×	×	NOUN
dti-1352	106	34	20	20	NUM
dti-1352	106	35	cm	cm	NOUN
dti-1352	106	36	)	)	PUNCT
dti-1352	106	37	nailed	nail	VERB
dti-1352	106	38	to	to	ADP
dti-1352	106	39	one	one	NUM
dti-1352	106	40	of	of	ADP
dti-1352	106	41	the	the	DET
dti-1352	106	42	walls	wall	NOUN
dti-1352	106	43	and	and	CCONJ
dti-1352	106	44	a	a	DET
dti-1352	106	45	plexiglas	plexiglas	NOUN
dti-1352	106	46	floor	floor	NOUN
dti-1352	106	47	.	.	PUNCT
dti-1352	107	1	a	a	DET
dti-1352	107	2	light	light	ADJ
dti-1352	107	3	bulb	bulb	NOUN
dti-1352	107	4	above	above	ADP
dti-1352	107	5	the	the	DET
dti-1352	107	6	central	central	ADJ
dti-1352	107	7	section	section	NOUN
dti-1352	107	8	provided	provide	VERB
dti-1352	107	9	constant	constant	ADJ
dti-1352	107	10	illumination	illumination	NOUN
dti-1352	107	11	of	of	ADP
dti-1352	107	12	approximately	approximately	ADV
dti-1352	107	13	100	100	NUM
dti-1352	107	14	lux	lux	NOUN
dti-1352	107	15	.	.	PUNCT
dti-1352	108	1	the	the	DET
dti-1352	108	2	nor	nor	CCONJ
dti-1352	108	3	http://www.la-press.com	http://www.la-press.com	X
dti-1352	108	4	gumuslu	gumuslu	NOUN
dti-1352	108	5	et	et	PROPN
dti-1352	108	6	al	al	PROPN
dti-1352	108	7	14	14	NUM
dti-1352	108	8	drug	drug	NOUN
dti-1352	108	9	target	target	NOUN
dti-1352	108	10	insights	insight	VERB
dti-1352	108	11	2014:8	2014:8	NUM
dti-1352	108	12	task	task	NOUN
dti-1352	108	13	procedure	procedure	NOUN
dti-1352	108	14	consisted	consist	VERB
dti-1352	108	15	of	of	ADP
dti-1352	108	16	the	the	DET
dti-1352	108	17	following	follow	VERB
dti-1352	108	18	three	three	NUM
dti-1352	108	19	components	component	NOUN
dti-1352	108	20	:	:	PUNCT
dti-1352	108	21	habituation	habituation	NOUN
dti-1352	108	22	,	,	PUNCT
dti-1352	108	23	training	training	NOUN
dti-1352	108	24	,	,	PUNCT
dti-1352	108	25	and	and	CCONJ
dti-1352	108	26	retention	retention	NOUN
dti-1352	108	27	.	.	PUNCT
dti-1352	109	1	each	each	DET
dti-1352	109	2	mouse	mouse	NOUN
dti-1352	109	3	was	be	AUX
dti-1352	109	4	individually	individually	ADV
dti-1352	109	5	habituated	habituate	VERB
dti-1352	109	6	to	to	ADP
dti-1352	109	7	the	the	DET
dti-1352	109	8	apparatus	apparatus	NOUN
dti-1352	109	9	for	for	ADP
dti-1352	109	10	five	five	NUM
dti-1352	109	11	minutes	minute	NOUN
dti-1352	109	12	in	in	ADP
dti-1352	109	13	the	the	DET
dti-1352	109	14	absence	absence	NOUN
dti-1352	109	15	of	of	ADP
dti-1352	109	16	objects	object	NOUN
dti-1352	109	17	(	(	PUNCT
dti-1352	109	18	habituation	habituation	NOUN
dti-1352	109	19	trial	trial	NOUN
dti-1352	109	20	)	)	PUNCT
dti-1352	109	21	.	.	PUNCT
dti-1352	110	1	the	the	DET
dti-1352	110	2	mouse	mouse	NOUN
dti-1352	110	3	was	be	AUX
dti-1352	110	4	placed	place	VERB
dti-1352	110	5	in	in	ADP
dti-1352	110	6	the	the	DET
dti-1352	110	7	apparatus	apparatus	NOUN
dti-1352	110	8	for	for	ADP
dti-1352	110	9	the	the	DET
dti-1352	110	10	training	training	NOUN
dti-1352	110	11	trial	trial	NOUN
dti-1352	110	12	and	and	CCONJ
dti-1352	110	13	two	two	NUM
dti-1352	110	14	identical	identical	ADJ
dti-1352	110	15	objects	object	NOUN
dti-1352	110	16	(	(	PUNCT
dti-1352	110	17	moon	moon	NOUN
dti-1352	110	18	or	or	CCONJ
dti-1352	110	19	butterfly	butterfly	NOUN
dti-1352	110	20	)	)	PUNCT
dti-1352	110	21	were	be	AUX
dti-1352	110	22	placed	place	VERB
dti-1352	110	23	in	in	ADP
dti-1352	110	24	a	a	DET
dti-1352	110	25	symmetrical	symmetrical	ADJ
dti-1352	110	26	position	position	NOUN
dti-1352	110	27	10	10	NUM
dti-1352	110	28	cm	cm	NOUN
dti-1352	110	29	above	above	ADP
dti-1352	110	30	the	the	DET
dti-1352	110	31	side	side	NOUN
dti-1352	110	32	wall	wall	NOUN
dti-1352	110	33	30	30	NUM
dti-1352	110	34	minutes	minute	NOUN
dti-1352	110	35	after	after	ADP
dti-1352	110	36	the	the	DET
dti-1352	110	37	habituation	habituation	NOUN
dti-1352	110	38	trial	trial	NOUN
dti-1352	110	39	.	.	PUNCT
dti-1352	111	1	the	the	DET
dti-1352	111	2	order	order	NOUN
dti-1352	111	3	of	of	ADP
dti-1352	111	4	objects	object	NOUN
dti-1352	111	5	used	use	VERB
dti-1352	111	6	for	for	ADP
dti-1352	111	7	each	each	DET
dti-1352	111	8	subject	subject	NOUN
dti-1352	111	9	per	per	ADP
dti-1352	111	10	trial	trial	NOUN
dti-1352	111	11	was	be	AUX
dti-1352	111	12	determined	determine	VERB
dti-1352	111	13	randomly	randomly	ADV
dti-1352	111	14	.	.	PUNCT
dti-1352	112	1	the	the	DET
dti-1352	112	2	total	total	ADJ
dti-1352	112	3	time	time	NOUN
dti-1352	112	4	spent	spend	VERB
dti-1352	112	5	exploring	explore	VERB
dti-1352	112	6	the	the	DET
dti-1352	112	7	two	two	NUM
dti-1352	112	8	objects	object	NOUN
dti-1352	112	9	was	be	AUX
dti-1352	112	10	recorded	record	VERB
dti-1352	112	11	by	by	ADP
dti-1352	112	12	the	the	DET
dti-1352	112	13	experimenter	experimenter	NOUN
dti-1352	112	14	over	over	ADP
dti-1352	112	15	five	five	NUM
dti-1352	112	16	minutes	minute	NOUN
dti-1352	112	17	.	.	PUNCT
dti-1352	113	1	exploration	exploration	NOUN
dti-1352	113	2	of	of	ADP
dti-1352	113	3	an	an	DET
dti-1352	113	4	object	object	NOUN
dti-1352	113	5	was	be	AUX
dti-1352	113	6	defined	define	VERB
dti-1352	113	7	as	as	ADP
dti-1352	113	8	directing	direct	VERB
dti-1352	113	9	the	the	DET
dti-1352	113	10	nose	nose	NOUN
dti-1352	113	11	toward	toward	ADP
dti-1352	113	12	the	the	DET
dti-1352	113	13	object	object	NOUN
dti-1352	113	14	and/or	and/or	CCONJ
dti-1352	113	15	touching	touch	VERB
dti-1352	113	16	it	it	PRON
dti-1352	113	17	with	with	ADP
dti-1352	113	18	the	the	DET
dti-1352	113	19	nose	nose	NOUN
dti-1352	113	20	.	.	PUNCT
dti-1352	114	1	after	after	ADP
dti-1352	114	2	a	a	DET
dti-1352	114	3	predetermined	predetermine	VERB
dti-1352	114	4	retention	retention	NOUN
dti-1352	114	5	interval	interval	NOUN
dti-1352	114	6	of	of	ADP
dti-1352	114	7	one	one	NUM
dti-1352	114	8	hour	hour	NOUN
dti-1352	114	9	,	,	PUNCT
dti-1352	114	10	the	the	DET
dti-1352	114	11	mouse	mouse	NOUN
dti-1352	114	12	was	be	AUX
dti-1352	114	13	placed	place	VERB
dti-1352	114	14	back	back	ADV
dti-1352	114	15	into	into	ADP
dti-1352	114	16	the	the	DET
dti-1352	114	17	apparatus	apparatus	NOUN
dti-1352	114	18	for	for	ADP
dti-1352	114	19	the	the	DET
dti-1352	114	20	retention	retention	NOUN
dti-1352	114	21	trial	trial	NOUN
dti-1352	114	22	;	;	PUNCT
dti-1352	114	23	however	however	ADV
dti-1352	114	24	,	,	PUNCT
dti-1352	114	25	during	during	ADP
dti-1352	114	26	this	this	DET
dti-1352	114	27	trial	trial	NOUN
dti-1352	114	28	,	,	PUNCT
dti-1352	114	29	two	two	NUM
dti-1352	114	30	dissimilar	dissimilar	ADJ
dti-1352	114	31	objects	object	NOUN
dti-1352	114	32	were	be	AUX
dti-1352	114	33	presented	present	VERB
dti-1352	114	34	,	,	PUNCT
dti-1352	114	35	a	a	DET
dti-1352	114	36	familiar	familiar	ADJ
dti-1352	114	37	one	one	NOUN
dti-1352	114	38	and	and	CCONJ
dti-1352	114	39	a	a	DET
dti-1352	114	40	new	new	ADJ
dti-1352	114	41	one	one	NUM
dti-1352	114	42	.	.	PUNCT
dti-1352	115	1	the	the	DET
dti-1352	115	2	object	object	NOUN
dti-1352	115	3	not	not	PART
dti-1352	115	4	used	use	VERB
dti-1352	115	5	in	in	ADP
dti-1352	115	6	the	the	DET
dti-1352	115	7	training	training	NOUN
dti-1352	115	8	trial	trial	NOUN
dti-1352	115	9	was	be	AUX
dti-1352	115	10	used	use	VERB
dti-1352	115	11	as	as	ADP
dti-1352	115	12	the	the	DET
dti-1352	115	13	novel	novel	ADJ
dti-1352	115	14	object	object	NOUN
dti-1352	115	15	in	in	ADP
dti-1352	115	16	the	the	DET
dti-1352	115	17	retention	retention	NOUN
dti-1352	115	18	trial	trial	NOUN
dti-1352	115	19	.	.	PUNCT
dti-1352	116	1	the	the	DET
dti-1352	116	2	animals	animal	NOUN
dti-1352	116	3	were	be	AUX
dti-1352	116	4	allowed	allow	VERB
dti-1352	116	5	to	to	PART
dti-1352	116	6	explore	explore	VERB
dti-1352	116	7	freely	freely	ADV
dti-1352	116	8	for	for	ADP
dti-1352	116	9	five	five	NUM
dti-1352	116	10	minutes	minute	NOUN
dti-1352	116	11	and	and	CCONJ
dti-1352	116	12	the	the	DET
dti-1352	116	13	time	time	NOUN
dti-1352	116	14	spent	spend	VERB
dti-1352	116	15	exploring	explore	VERB
dti-1352	116	16	each	each	DET
dti-1352	116	17	object	object	NOUN
dti-1352	116	18	was	be	AUX
dti-1352	116	19	recorded	record	VERB
dti-1352	116	20	.	.	PUNCT
dti-1352	117	1	if	if	SCONJ
dti-1352	117	2	recognition	recognition	NOUN
dti-1352	117	3	memory	memory	NOUN
dti-1352	117	4	was	be	AUX
dti-1352	117	5	intact	intact	ADJ
dti-1352	117	6	,	,	PUNCT
dti-1352	117	7	the	the	DET
dti-1352	117	8	mouse	mouse	NOUN
dti-1352	117	9	would	would	AUX
dti-1352	117	10	be	be	AUX
dti-1352	117	11	expected	expect	VERB
dti-1352	117	12	to	to	PART
dti-1352	117	13	spend	spend	VERB
dti-1352	117	14	more	more	ADJ
dti-1352	117	15	time	time	NOUN
dti-1352	117	16	exploring	explore	VERB
dti-1352	117	17	the	the	DET
dti-1352	117	18	novel	novel	NOUN
dti-1352	117	19	object.30	object.30	NOUN
dti-1352	117	20	the	the	DET
dti-1352	117	21	ratio	ratio	NOUN
dti-1352	117	22	index	index	NOUN
dti-1352	117	23	(	(	PUNCT
dti-1352	117	24	ri	ri	NOUN
dti-1352	117	25	)	)	PUNCT
dti-1352	117	26	was	be	AUX
dti-1352	117	27	calculated	calculate	VERB
dti-1352	117	28	as	as	ADP
dti-1352	117	29	the	the	DET
dti-1352	117	30	time	time	NOUN
dti-1352	117	31	spent	spend	VERB
dti-1352	117	32	exploring	explore	VERB
dti-1352	117	33	the	the	DET
dti-1352	117	34	new	new	ADJ
dti-1352	117	35	object	object	NOUN
dti-1352	117	36	(	(	PUNCT
dti-1352	117	37	n	n	CCONJ
dti-1352	117	38	)	)	PUNCT
dti-1352	117	39	divided	divide	VERB
dti-1352	117	40	by	by	ADP
dti-1352	117	41	the	the	DET
dti-1352	117	42	total	total	ADJ
dti-1352	117	43	time	time	NOUN
dti-1352	117	44	exploring	explore	VERB
dti-1352	117	45	both	both	DET
dti-1352	117	46	objects	object	NOUN
dti-1352	117	47	(	(	PUNCT
dti-1352	117	48	n	n	NOUN
dti-1352	117	49	+	+	X
dti-1352	117	50	r	r	NOUN
dti-1352	117	51	)	)	PUNCT
dti-1352	117	52	multiplied	multiply	VERB
dti-1352	117	53	by	by	ADP
dti-1352	117	54	100	100	NUM
dti-1352	117	55	.	.	PUNCT
dti-1352	118	1	a	a	DET
dti-1352	118	2	higher	high	ADJ
dti-1352	118	3	ri	ri	NOUN
dti-1352	118	4	was	be	AUX
dti-1352	118	5	considered	consider	VERB
dti-1352	118	6	to	to	PART
dti-1352	118	7	reflect	reflect	VERB
dti-1352	118	8	greater	great	ADJ
dti-1352	118	9	memory	memory	NOUN
dti-1352	118	10	retention	retention	NOUN
dti-1352	118	11	.	.	PUNCT
dti-1352	119	1	mwm	mwm	NOUN
dti-1352	119	2	.	.	PUNCT
dti-1352	120	1	the	the	DET
dti-1352	120	2	mwm	mwm	NOUN
dti-1352	120	3	was	be	AUX
dti-1352	120	4	a	a	DET
dti-1352	120	5	circular	circular	ADJ
dti-1352	120	6	pool	pool	NOUN
dti-1352	120	7	(	(	PUNCT
dti-1352	120	8	90	90	NUM
dti-1352	120	9	cm	cm	NOUN
dti-1352	120	10	diameter	diameter	NOUN
dti-1352	120	11	and	and	CCONJ
dti-1352	120	12	30	30	NUM
dti-1352	120	13	cm	cm	NOUN
dti-1352	120	14	height	height	NOUN
dti-1352	120	15	)	)	PUNCT
dti-1352	120	16	filled	fill	VERB
dti-1352	120	17	with	with	ADP
dti-1352	120	18	water	water	NOUN
dti-1352	120	19	(	(	PUNCT
dti-1352	120	20	22ºc	22ºc	ADJ
dti-1352	120	21	)	)	PUNCT
dti-1352	120	22	to	to	ADP
dti-1352	120	23	a	a	DET
dti-1352	120	24	depth	depth	NOUN
dti-1352	120	25	of	of	ADP
dti-1352	120	26	14	14	NUM
dti-1352	120	27	cm	cm	NOUN
dti-1352	120	28	and	and	CCONJ
dti-1352	120	29	rendered	render	VERB
dti-1352	120	30	opaque	opaque	NOUN
dti-1352	120	31	by	by	ADP
dti-1352	120	32	the	the	DET
dti-1352	120	33	addition	addition	NOUN
dti-1352	120	34	of	of	ADP
dti-1352	120	35	small	small	ADJ
dti-1352	120	36	black	black	ADJ
dti-1352	120	37	balls	ball	NOUN
dti-1352	120	38	.	.	PUNCT
dti-1352	121	1	the	the	DET
dti-1352	121	2	pool	pool	NOUN
dti-1352	121	3	was	be	AUX
dti-1352	121	4	located	locate	VERB
dti-1352	121	5	in	in	ADP
dti-1352	121	6	a	a	DET
dti-1352	121	7	dimly	dimly	ADV
dti-1352	121	8	lit	light	VERB
dti-1352	121	9	,	,	PUNCT
dti-1352	121	10	soundproof	soundproof	ADJ
dti-1352	121	11	test	test	NOUN
dti-1352	121	12	room	room	NOUN
dti-1352	121	13	with	with	ADP
dti-1352	121	14	a	a	DET
dti-1352	121	15	various	various	ADJ
dti-1352	121	16	visual	visual	ADJ
dti-1352	121	17	cues	cue	NOUN
dti-1352	121	18	,	,	PUNCT
dti-1352	121	19	including	include	VERB
dti-1352	121	20	a	a	DET
dti-1352	121	21	white	white	ADJ
dti-1352	121	22	and	and	CCONJ
dti-1352	121	23	black	black	ADJ
dti-1352	121	24	poster	poster	NOUN
dti-1352	121	25	on	on	ADP
dti-1352	121	26	the	the	DET
dti-1352	121	27	wall	wall	NOUN
dti-1352	121	28	,	,	PUNCT
dti-1352	121	29	a	a	DET
dti-1352	121	30	halogen	halogen	PROPN
dti-1352	121	31	lamp	lamp	NOUN
dti-1352	121	32	,	,	PUNCT
dti-1352	121	33	a	a	DET
dti-1352	121	34	camera	camera	NOUN
dti-1352	121	35	,	,	PUNCT
dti-1352	121	36	and	and	CCONJ
dti-1352	121	37	the	the	DET
dti-1352	121	38	experimenter	experimenter	NOUN
dti-1352	121	39	.	.	PUNCT
dti-1352	122	1	the	the	DET
dti-1352	122	2	maze	maze	NOUN
dti-1352	122	3	was	be	AUX
dti-1352	122	4	divided	divide	VERB
dti-1352	122	5	into	into	ADP
dti-1352	122	6	four	four	NUM
dti-1352	122	7	quadrants	quadrant	NOUN
dti-1352	122	8	,	,	PUNCT
dti-1352	122	9	and	and	CCONJ
dti-1352	122	10	three	three	NUM
dti-1352	122	11	equally	equally	ADV
dti-1352	122	12	spaced	space	VERB
dti-1352	122	13	points	point	NOUN
dti-1352	122	14	served	serve	VERB
dti-1352	122	15	as	as	ADP
dti-1352	122	16	starting	start	VERB
dti-1352	122	17	positions	position	NOUN
dti-1352	122	18	around	around	ADP
dti-1352	122	19	the	the	DET
dti-1352	122	20	edge	edge	NOUN
dti-1352	122	21	of	of	ADP
dti-1352	122	22	the	the	DET
dti-1352	122	23	pool	pool	NOUN
dti-1352	122	24	.	.	PUNCT
dti-1352	123	1	the	the	DET
dti-1352	123	2	order	order	NOUN
dti-1352	123	3	of	of	ADP
dti-1352	123	4	the	the	DET
dti-1352	123	5	release	release	NOUN
dti-1352	123	6	positions	position	NOUN
dti-1352	123	7	varied	vary	VERB
dti-1352	123	8	systematically	systematically	ADV
dti-1352	123	9	throughout	throughout	ADP
dti-1352	123	10	the	the	DET
dti-1352	123	11	experiment	experiment	NOUN
dti-1352	123	12	.	.	PUNCT
dti-1352	124	1	a	a	DET
dti-1352	124	2	circular	circular	ADJ
dti-1352	124	3	escape	escape	NOUN
dti-1352	124	4	platform	platform	NOUN
dti-1352	124	5	(	(	PUNCT
dti-1352	124	6	6	6	NUM
dti-1352	124	7	cm	cm	NOUN
dti-1352	124	8	diameter	diameter	NOUN
dti-1352	124	9	and	and	CCONJ
dti-1352	124	10	12	12	NUM
dti-1352	124	11	cm	cm	NOUN
dti-1352	124	12	high	high	ADJ
dti-1352	124	13	)	)	PUNCT
dti-1352	124	14	was	be	AUX
dti-1352	124	15	located	locate	VERB
dti-1352	124	16	in	in	ADP
dti-1352	124	17	one	one	NUM
dti-1352	124	18	quadrant	quadrant	NOUN
dti-1352	124	19	1	1	NUM
dti-1352	124	20	cm	cm	NOUN
dti-1352	124	21	above	above	ADP
dti-1352	124	22	the	the	DET
dti-1352	124	23	water	water	NOUN
dti-1352	124	24	surface	surface	NOUN
dti-1352	124	25	during	during	ADP
dti-1352	124	26	the	the	DET
dti-1352	124	27	familiarization	familiarization	NOUN
dti-1352	124	28	session	session	NOUN
dti-1352	124	29	and	and	CCONJ
dti-1352	124	30	1	1	NUM
dti-1352	124	31	cm	cm	NOUN
dti-1352	124	32	below	below	ADP
dti-1352	124	33	the	the	DET
dti-1352	124	34	water	water	NOUN
dti-1352	124	35	surface	surface	NOUN
dti-1352	124	36	during	during	ADP
dti-1352	124	37	the	the	DET
dti-1352	124	38	other	other	ADJ
dti-1352	124	39	sessions	session	NOUN
dti-1352	124	40	.	.	PUNCT
dti-1352	125	1	video	video	NOUN
dti-1352	125	2	tracking	tracking	NOUN
dti-1352	125	3	was	be	AUX
dti-1352	125	4	conducted	conduct	VERB
dti-1352	125	5	with	with	ADP
dti-1352	125	6	a	a	DET
dti-1352	125	7	video	video	NOUN
dti-1352	125	8	camera	camera	NOUN
dti-1352	125	9	focused	focus	VERB
dti-1352	125	10	on	on	ADP
dti-1352	125	11	the	the	DET
dti-1352	125	12	full	full	ADJ
dti-1352	125	13	diameter	diameter	NOUN
dti-1352	125	14	of	of	ADP
dti-1352	125	15	the	the	DET
dti-1352	125	16	pool	pool	NOUN
dti-1352	125	17	.	.	PUNCT
dti-1352	126	1	the	the	DET
dti-1352	126	2	navigation	navigation	NOUN
dti-1352	126	3	parameters	parameter	NOUN
dti-1352	126	4	were	be	AUX
dti-1352	126	5	analyzed	analyze	VERB
dti-1352	126	6	using	use	VERB
dti-1352	126	7	the	the	DET
dti-1352	126	8	ethovision	ethovision	NOUN
dti-1352	126	9	3.1	3.1	NUM
dti-1352	126	10	video	video	NOUN
dti-1352	126	11	analysis	analysis	NOUN
dti-1352	126	12	system	system	NOUN
dti-1352	126	13	(	(	PUNCT
dti-1352	126	14	noldus	noldus	NOUN
dti-1352	126	15	,	,	PUNCT
dti-1352	126	16	the	the	DET
dti-1352	126	17	netherlands	netherlands	PROPN
dti-1352	126	18	)	)	PUNCT
dti-1352	126	19	.	.	PUNCT
dti-1352	127	1	the	the	DET
dti-1352	127	2	mice	mouse	NOUN
dti-1352	127	3	were	be	AUX
dti-1352	127	4	trained	train	VERB
dti-1352	127	5	in	in	ADP
dti-1352	127	6	the	the	DET
dti-1352	127	7	mwm	mwm	NOUN
dti-1352	127	8	five	five	NUM
dti-1352	127	9	times	time	NOUN
dti-1352	127	10	daily	daily	ADJ
dti-1352	127	11	(	(	PUNCT
dti-1352	127	12	familiarization	familiarization	NOUN
dti-1352	127	13	session	session	NOUN
dti-1352	127	14	,	,	PUNCT
dti-1352	127	15	s1	s1	NOUN
dti-1352	127	16	,	,	PUNCT
dti-1352	127	17	s2	s2	PROPN
dti-1352	127	18	,	,	PUNCT
dti-1352	127	19	s3	s3	PROPN
dti-1352	127	20	,	,	PUNCT
dti-1352	127	21	s4	s4	PROPN
dti-1352	127	22	)	)	PUNCT
dti-1352	127	23	.	.	PUNCT
dti-1352	128	1	one	one	NUM
dti-1352	128	2	familiarization	familiarization	NOUN
dti-1352	128	3	and	and	CCONJ
dti-1352	128	4	four	four	NUM
dti-1352	128	5	acquisition	acquisition	NOUN
dti-1352	128	6	sessions	session	NOUN
dti-1352	128	7	were	be	AUX
dti-1352	128	8	performed	perform	VERB
dti-1352	128	9	using	use	VERB
dti-1352	128	10	the	the	DET
dti-1352	128	11	mwm	mwm	NOUN
dti-1352	128	12	.	.	PUNCT
dti-1352	128	13	during	during	ADP
dti-1352	128	14	the	the	DET
dti-1352	128	15	familiarization	familiarization	NOUN
dti-1352	128	16	session	session	NOUN
dti-1352	128	17	and	and	CCONJ
dti-1352	128	18	acquisition	acquisition	NOUN
dti-1352	128	19	phase	phase	NOUN
dti-1352	128	20	of	of	ADP
dti-1352	128	21	the	the	DET
dti-1352	128	22	experiment	experiment	NOUN
dti-1352	128	23	,	,	PUNCT
dti-1352	128	24	each	each	DET
dti-1352	128	25	mouse	mouse	NOUN
dti-1352	128	26	was	be	AUX
dti-1352	128	27	subjected	subject	VERB
dti-1352	128	28	to	to	ADP
dti-1352	128	29	three	three	NUM
dti-1352	128	30	trials	trial	NOUN
dti-1352	128	31	.	.	PUNCT
dti-1352	129	1	the	the	DET
dti-1352	129	2	delay	delay	NOUN
dti-1352	129	3	between	between	ADP
dti-1352	129	4	the	the	DET
dti-1352	129	5	trials	trial	NOUN
dti-1352	129	6	was	be	AUX
dti-1352	129	7	60	60	NUM
dti-1352	129	8	seconds	second	NOUN
dti-1352	129	9	,	,	PUNCT
dti-1352	129	10	and	and	CCONJ
dti-1352	129	11	a	a	DET
dti-1352	129	12	one	one	NUM
dti-1352	129	13	-	-	PUNCT
dti-1352	129	14	day	day	NOUN
dti-1352	129	15	interval	interval	NOUN
dti-1352	129	16	was	be	AUX
dti-1352	129	17	used	use	VERB
dti-1352	129	18	between	between	ADP
dti-1352	129	19	each	each	DET
dti-1352	129	20	session	session	NOUN
dti-1352	129	21	.	.	PUNCT
dti-1352	130	1	for	for	ADP
dti-1352	130	2	each	each	DET
dti-1352	130	3	trial	trial	NOUN
dti-1352	130	4	,	,	PUNCT
dti-1352	130	5	the	the	DET
dti-1352	130	6	mouse	mouse	NOUN
dti-1352	130	7	was	be	AUX
dti-1352	130	8	taken	take	VERB
dti-1352	130	9	from	from	ADP
dti-1352	130	10	the	the	DET
dti-1352	130	11	home	home	NOUN
dti-1352	130	12	cage	cage	NOUN
dti-1352	130	13	and	and	CCONJ
dti-1352	130	14	placed	place	VERB
dti-1352	130	15	into	into	ADP
dti-1352	130	16	the	the	DET
dti-1352	130	17	water	water	NOUN
dti-1352	130	18	maze	maze	NOUN
dti-1352	130	19	at	at	ADP
dti-1352	130	20	one	one	NUM
dti-1352	130	21	of	of	ADP
dti-1352	130	22	three	three	NUM
dti-1352	130	23	randomly	randomly	ADV
dti-1352	130	24	determined	determine	VERB
dti-1352	130	25	locations	location	NOUN
dti-1352	130	26	with	with	ADP
dti-1352	130	27	its	its	PRON
dti-1352	130	28	head	head	NOUN
dti-1352	130	29	facing	face	VERB
dti-1352	130	30	the	the	DET
dti-1352	130	31	center	center	NOUN
dti-1352	130	32	of	of	ADP
dti-1352	130	33	the	the	DET
dti-1352	130	34	water	water	NOUN
dti-1352	130	35	maze	maze	NOUN
dti-1352	130	36	.	.	PUNCT
dti-1352	131	1	after	after	SCONJ
dti-1352	131	2	the	the	DET
dti-1352	131	3	mouse	mouse	NOUN
dti-1352	131	4	found	find	VERB
dti-1352	131	5	and	and	CCONJ
dti-1352	131	6	climbed	climb	VERB
dti-1352	131	7	onto	onto	ADP
dti-1352	131	8	the	the	DET
dti-1352	131	9	platform	platform	NOUN
dti-1352	131	10	,	,	PUNCT
dti-1352	131	11	the	the	DET
dti-1352	131	12	trial	trial	NOUN
dti-1352	131	13	was	be	AUX
dti-1352	131	14	stopped	stop	VERB
dti-1352	131	15	,	,	PUNCT
dti-1352	131	16	and	and	CCONJ
dti-1352	131	17	the	the	DET
dti-1352	131	18	escape	escape	NOUN
dti-1352	131	19	latency	latency	NOUN
dti-1352	131	20	was	be	AUX
dti-1352	131	21	recorded	record	VERB
dti-1352	131	22	.	.	PUNCT
dti-1352	132	1	if	if	SCONJ
dti-1352	132	2	the	the	DET
dti-1352	132	3	mouse	mouse	NOUN
dti-1352	132	4	did	do	AUX
dti-1352	132	5	not	not	PART
dti-1352	132	6	climb	climb	VERB
dti-1352	132	7	onto	onto	ADP
dti-1352	132	8	the	the	DET
dti-1352	132	9	platform	platform	NOUN
dti-1352	132	10	in	in	ADP
dti-1352	132	11	60	60	NUM
dti-1352	132	12	seconds	second	NOUN
dti-1352	132	13	,	,	PUNCT
dti-1352	132	14	the	the	DET
dti-1352	132	15	trial	trial	NOUN
dti-1352	132	16	was	be	AUX
dti-1352	132	17	stopped	stop	VERB
dti-1352	132	18	,	,	PUNCT
dti-1352	132	19	and	and	CCONJ
dti-1352	132	20	the	the	DET
dti-1352	132	21	experimenter	experimenter	NOUN
dti-1352	132	22	guided	guide	VERB
dti-1352	132	23	the	the	DET
dti-1352	132	24	mouse	mouse	NOUN
dti-1352	132	25	to	to	ADP
dti-1352	132	26	the	the	DET
dti-1352	132	27	platform	platform	NOUN
dti-1352	132	28	;	;	PUNCT
dti-1352	132	29	an	an	DET
dti-1352	132	30	escape	escape	NOUN
dti-1352	132	31	latency	latency	NOUN
dti-1352	132	32	of	of	ADP
dti-1352	132	33	60	60	NUM
dti-1352	132	34	seconds	second	NOUN
dti-1352	132	35	was	be	AUX
dti-1352	132	36	recorded	record	VERB
dti-1352	132	37	.	.	PUNCT
dti-1352	133	1	a	a	DET
dti-1352	133	2	“	"	PUNCT
dti-1352	133	3	probe	probe	NOUN
dti-1352	133	4	trial	trial	NOUN
dti-1352	133	5	”	"	PUNCT
dti-1352	133	6	was	be	AUX
dti-1352	133	7	used	use	VERB
dti-1352	133	8	to	to	PART
dti-1352	133	9	assess	assess	VERB
dti-1352	133	10	the	the	DET
dti-1352	133	11	spatial	spatial	ADJ
dti-1352	133	12	memory	memory	NOUN
dti-1352	133	13	retention	retention	NOUN
dti-1352	133	14	of	of	ADP
dti-1352	133	15	the	the	DET
dti-1352	133	16	location	location	NOUN
dti-1352	133	17	of	of	ADP
dti-1352	133	18	the	the	DET
dti-1352	133	19	hidden	hide	VERB
dti-1352	133	20	platform	platform	NOUN
dti-1352	133	21	24	24	NUM
dti-1352	133	22	hours	hour	NOUN
dti-1352	133	23	after	after	ADP
dti-1352	133	24	the	the	DET
dti-1352	133	25	last	last	ADJ
dti-1352	133	26	acquisition	acquisition	NOUN
dti-1352	133	27	session	session	NOUN
dti-1352	133	28	.	.	PUNCT
dti-1352	134	1	during	during	ADP
dti-1352	134	2	this	this	DET
dti-1352	134	3	trial	trial	NOUN
dti-1352	134	4	,	,	PUNCT
dti-1352	134	5	the	the	DET
dti-1352	134	6	platform	platform	NOUN
dti-1352	134	7	was	be	AUX
dti-1352	134	8	removed	remove	VERB
dti-1352	134	9	from	from	ADP
dti-1352	134	10	the	the	DET
dti-1352	134	11	maze	maze	NOUN
dti-1352	134	12	,	,	PUNCT
dti-1352	134	13	and	and	CCONJ
dti-1352	134	14	the	the	DET
dti-1352	134	15	mouse	mouse	NOUN
dti-1352	134	16	was	be	AUX
dti-1352	134	17	allowed	allow	VERB
dti-1352	134	18	to	to	PART
dti-1352	134	19	search	search	VERB
dti-1352	134	20	the	the	DET
dti-1352	134	21	pool	pool	NOUN
dti-1352	134	22	for	for	ADP
dti-1352	134	23	60	60	NUM
dti-1352	134	24	seconds	second	NOUN
dti-1352	134	25	.	.	PUNCT
dti-1352	135	1	the	the	DET
dti-1352	135	2	percent	percent	NOUN
dti-1352	135	3	of	of	ADP
dti-1352	135	4	time	time	NOUN
dti-1352	135	5	spent	spend	VERB
dti-1352	135	6	in	in	ADP
dti-1352	135	7	each	each	DET
dti-1352	135	8	quadrant	quadrant	NOUN
dti-1352	135	9	was	be	AUX
dti-1352	135	10	recorded	record	VERB
dti-1352	135	11	.	.	PUNCT
dti-1352	136	1	tissue	tissue	NOUN
dti-1352	136	2	sampling	sampling	NOUN
dti-1352	136	3	,	,	PUNCT
dti-1352	136	4	rna	rna	NOUN
dti-1352	136	5	isolation	isolation	NOUN
dti-1352	136	6	,	,	PUNCT
dti-1352	136	7	and	and	CCONJ
dti-1352	136	8	quantitative	quantitative	ADJ
dti-1352	136	9	rt	rt	NOUN
dti-1352	136	10	-	-	PUNCT
dti-1352	136	11	pcr	pcr	NOUN
dti-1352	136	12	.	.	PUNCT
dti-1352	137	1	one	one	NUM
dti-1352	137	2	day	day	NOUN
dti-1352	137	3	after	after	ADP
dti-1352	137	4	the	the	DET
dti-1352	137	5	final	final	ADJ
dti-1352	137	6	stress	stress	NOUN
dti-1352	137	7	session	session	NOUN
dti-1352	137	8	,	,	PUNCT
dti-1352	137	9	the	the	DET
dti-1352	137	10	mice	mouse	NOUN
dti-1352	137	11	were	be	AUX
dti-1352	137	12	decapitated	decapitate	VERB
dti-1352	137	13	by	by	ADP
dti-1352	137	14	cervical	cervical	ADJ
dti-1352	137	15	dislocation	dislocation	NOUN
dti-1352	137	16	.	.	PUNCT
dti-1352	138	1	the	the	DET
dti-1352	138	2	left	left	ADJ
dti-1352	138	3	and	and	CCONJ
dti-1352	138	4	right	right	ADJ
dti-1352	138	5	hippocampi	hippocampi	ADJ
dti-1352	138	6	were	be	AUX
dti-1352	138	7	surgically	surgically	ADV
dti-1352	138	8	removed	remove	VERB
dti-1352	138	9	and	and	CCONJ
dti-1352	138	10	stored	store	VERB
dti-1352	138	11	in	in	ADP
dti-1352	138	12	liquid	liquid	ADJ
dti-1352	138	13	nitrogen	nitrogen	NOUN
dti-1352	138	14	.	.	PUNCT
dti-1352	139	1	total	total	ADJ
dti-1352	139	2	rna	rna	PROPN
dti-1352	139	3	was	be	AUX
dti-1352	139	4	isolated	isolate	VERB
dti-1352	139	5	with	with	ADP
dti-1352	139	6	the	the	DET
dti-1352	139	7	rneasy	rneasy	NOUN
dti-1352	139	8	mini	mini	NOUN
dti-1352	139	9	kit	kit	NOUN
dti-1352	139	10	extraction	extraction	NOUN
dti-1352	139	11	procedure	procedure	NOUN
dti-1352	139	12	(	(	PUNCT
dti-1352	139	13	qiagen	qiagen	PROPN
dti-1352	139	14	,	,	PUNCT
dti-1352	139	15	valencia	valencia	PROPN
dti-1352	139	16	,	,	PUNCT
dti-1352	139	17	ca	ca	PROPN
dti-1352	139	18	,	,	PUNCT
dti-1352	139	19	usa	usa	PROPN
dti-1352	139	20	)	)	PUNCT
dti-1352	139	21	.	.	PUNCT
dti-1352	140	1	briefly	briefly	ADV
dti-1352	140	2	,	,	PUNCT
dti-1352	140	3	tissues	tissue	NOUN
dti-1352	140	4	were	be	AUX
dti-1352	140	5	homogenized	homogenize	VERB
dti-1352	140	6	in	in	ADP
dti-1352	140	7	rlt	rlt	NOUN
dti-1352	140	8	lysis	lysis	NOUN
dti-1352	140	9	buffer	buffer	NOUN
dti-1352	140	10	containing	contain	VERB
dti-1352	140	11	β	β	NOUN
dti-1352	140	12	-	-	NOUN
dti-1352	140	13	mercaptoethanol	mercaptoethanol	NOUN
dti-1352	140	14	using	use	VERB
dti-1352	140	15	a	a	DET
dti-1352	140	16	thermo	thermo	NOUN
dti-1352	140	17	savant	savant	NOUN
dti-1352	140	18	fastprep	fastprep	ADJ
dti-1352	140	19	fp120	fp120	ADJ
dti-1352	140	20	homogenizer	homogenizer	NOUN
dti-1352	140	21	.	.	PUNCT
dti-1352	141	1	sample	sample	NOUN
dti-1352	141	2	homogenates	homogenate	NOUN
dti-1352	141	3	were	be	AUX
dti-1352	141	4	applied	apply	VERB
dti-1352	141	5	to	to	PART
dti-1352	141	6	rneasy	rneasy	VERB
dti-1352	141	7	mini	mini	ADJ
dti-1352	141	8	spin	spin	NOUN
dti-1352	141	9	columns	column	NOUN
dti-1352	141	10	(	(	PUNCT
dti-1352	141	11	qiagen	qiagen	PROPN
dti-1352	141	12	)	)	PUNCT
dti-1352	141	13	and	and	CCONJ
dti-1352	141	14	processed	process	VERB
dti-1352	141	15	according	accord	VERB
dti-1352	141	16	to	to	ADP
dti-1352	141	17	the	the	DET
dti-1352	141	18	manufacturer	manufacturer	NOUN
dti-1352	141	19	’s	’s	PART
dti-1352	141	20	instructions	instruction	NOUN
dti-1352	141	21	.	.	PUNCT
dti-1352	142	1	an	an	DET
dti-1352	142	2	on	on	ADP
dti-1352	142	3	-	-	PUNCT
dti-1352	142	4	column	column	NOUN
dti-1352	142	5	dnase	dnase	NOUN
dti-1352	142	6	digestion	digestion	NOUN
dti-1352	142	7	was	be	AUX
dti-1352	142	8	performed	perform	VERB
dti-1352	142	9	to	to	PART
dti-1352	142	10	remove	remove	VERB
dti-1352	142	11	any	any	DET
dti-1352	142	12	residual	residual	ADJ
dti-1352	142	13	genomic	genomic	NOUN
dti-1352	142	14	dna	dna	NOUN
dti-1352	142	15	contamination	contamination	NOUN
dti-1352	142	16	.	.	PUNCT
dti-1352	143	1	rna	rna	NOUN
dti-1352	143	2	samples	sample	NOUN
dti-1352	143	3	were	be	AUX
dti-1352	143	4	eluted	elute	VERB
dti-1352	143	5	in	in	ADP
dti-1352	143	6	rnase	rnase	NOUN
dti-1352	143	7	-	-	PUNCT
dti-1352	143	8	free	free	ADJ
dti-1352	143	9	water	water	NOUN
dti-1352	143	10	,	,	PUNCT
dti-1352	143	11	and	and	CCONJ
dti-1352	143	12	the	the	DET
dti-1352	143	13	concentration	concentration	NOUN
dti-1352	143	14	was	be	AUX
dti-1352	143	15	measured	measure	VERB
dti-1352	143	16	spectrophotometrically	spectrophotometrically	ADV
dti-1352	143	17	using	use	VERB
dti-1352	143	18	the	the	DET
dti-1352	143	19	nanodrop	nanodrop	NOUN
dti-1352	143	20	nd-1000	nd-1000	NOUN
dti-1352	143	21	spectrophotometer	spectrophotometer	NOUN
dti-1352	143	22	(	(	PUNCT
dti-1352	143	23	nanodrop	nanodrop	NOUN
dti-1352	143	24	nd-1000	nd-1000	PROPN
dti-1352	143	25	;	;	PUNCT
dti-1352	143	26	nanodrop	nanodrop	NOUN
dti-1352	143	27	technologies	technologies	PROPN
dti-1352	143	28	,	,	PUNCT
dti-1352	143	29	wilmington	wilmington	PROPN
dti-1352	143	30	,	,	PUNCT
dti-1352	143	31	de	de	PROPN
dti-1352	143	32	)	)	PUNCT
dti-1352	143	33	.	.	PUNCT
dti-1352	144	1	subsequently	subsequently	ADV
dti-1352	144	2	,	,	PUNCT
dti-1352	144	3	cdna	cdna	PROPN
dti-1352	144	4	was	be	AUX
dti-1352	144	5	synthesized	synthesize	VERB
dti-1352	144	6	using	use	VERB
dti-1352	144	7	a	a	DET
dti-1352	144	8	revertaid	revertaid	ADJ
dti-1352	144	9	first	first	ADJ
dti-1352	144	10	strand	strand	NOUN
dti-1352	144	11	cdna	cdna	PROPN
dti-1352	144	12	synthesis	synthesis	NOUN
dti-1352	144	13	kit	kit	NOUN
dti-1352	144	14	(	(	PUNCT
dti-1352	144	15	fermentas	fermentas	PROPN
dti-1352	144	16	inc	inc	PROPN
dti-1352	144	17	.	.	PROPN
dti-1352	144	18	,	,	PUNCT
dti-1352	144	19	maryland	maryland	PROPN
dti-1352	144	20	,	,	PUNCT
dti-1352	144	21	usa	usa	PROPN
dti-1352	144	22	)	)	PUNCT
dti-1352	144	23	.	.	PUNCT
dti-1352	145	1	quantitative	quantitative	ADJ
dti-1352	145	2	rt	rt	PROPN
dti-1352	145	3	-	-	PUNCT
dti-1352	145	4	pcr	pcr	PROPN
dti-1352	145	5	was	be	AUX
dti-1352	145	6	performed	perform	VERB
dti-1352	145	7	according	accord	VERB
dti-1352	145	8	to	to	ADP
dti-1352	145	9	the	the	DET
dti-1352	145	10	methods	method	NOUN
dti-1352	145	11	described	describe	VERB
dti-1352	145	12	in	in	ADP
dti-1352	145	13	previous	previous	ADJ
dti-1352	145	14	studies.32,33	studies.32,33	NOUN
dti-1352	145	15	standard	standard	ADJ
dti-1352	145	16	curves	curve	NOUN
dti-1352	145	17	were	be	AUX
dti-1352	145	18	obtained	obtain	VERB
dti-1352	145	19	via	via	ADP
dti-1352	145	20	serial	serial	ADJ
dti-1352	145	21	dilutions	dilution	NOUN
dti-1352	145	22	of	of	ADP
dti-1352	145	23	the	the	DET
dti-1352	145	24	beta	beta	NOUN
dti-1352	145	25	-	-	PUNCT
dti-1352	145	26	globulin	globulin	NOUN
dti-1352	145	27	gene	gene	NOUN
dti-1352	145	28	.	.	PUNCT
dti-1352	146	1	primers	primer	NOUN
dti-1352	146	2	specific	specific	ADJ
dti-1352	146	3	to	to	ADP
dti-1352	146	4	the	the	DET
dti-1352	146	5	genes	gene	NOUN
dti-1352	146	6	under	under	ADP
dti-1352	146	7	investigation	investigation	NOUN
dti-1352	146	8	(	(	PUNCT
dti-1352	146	9	table	table	NOUN
dti-1352	146	10	1	1	NUM
dti-1352	146	11	)	)	PUNCT
dti-1352	146	12	were	be	AUX
dti-1352	146	13	obtained	obtain	VERB
dti-1352	146	14	from	from	ADP
dti-1352	146	15	integrated	integrate	VERB
dti-1352	146	16	dna	dna	PROPN
dti-1352	146	17	technologies	technology	NOUN
dti-1352	146	18	(	(	PUNCT
dti-1352	146	19	iowa	iowa	PROPN
dti-1352	146	20	,	,	PUNCT
dti-1352	146	21	usa	usa	PROPN
dti-1352	146	22	)	)	PUNCT
dti-1352	146	23	and	and	CCONJ
dti-1352	146	24	iontek	iontek	PROPN
dti-1352	146	25	inc	inc	PROPN
dti-1352	146	26	.	.	PROPN
dti-1352	147	1	(	(	PUNCT
dti-1352	147	2	merter	merter	NOUN
dti-1352	147	3	,	,	PUNCT
dti-1352	147	4	istanbul	istanbul	PROPN
dti-1352	147	5	,	,	PUNCT
dti-1352	147	6	turkey	turkey	PROPN
dti-1352	147	7	)	)	PUNCT
dti-1352	147	8	.	.	PUNCT
dti-1352	148	1	the	the	DET
dti-1352	148	2	gene	gene	NOUN
dti-1352	148	3	expression	expression	NOUN
dti-1352	148	4	values	value	NOUN
dti-1352	148	5	obtained	obtain	VERB
dti-1352	148	6	were	be	AUX
dti-1352	148	7	normalized	normalize	VERB
dti-1352	148	8	using	use	VERB
dti-1352	148	9	the	the	DET
dti-1352	148	10	bact	bact	NOUN
dti-1352	148	11	housekeeping	housekeeping	NOUN
dti-1352	148	12	gene	gene	NOUN
dti-1352	148	13	.	.	PUNCT
dti-1352	149	1	gene	gene	NOUN
dti-1352	149	2	expression	expression	NOUN
dti-1352	149	3	levels	level	NOUN
dti-1352	149	4	were	be	AUX
dti-1352	149	5	calculated	calculate	VERB
dti-1352	149	6	with	with	ADP
dti-1352	149	7	the	the	DET
dti-1352	149	8	rest	rest	NOUN
dti-1352	149	9	(	(	PUNCT
dti-1352	149	10	relative	relative	ADJ
dti-1352	149	11	expression	expression	NOUN
dti-1352	149	12	software	software	NOUN
dti-1352	149	13	tool	tool	NOUN
dti-1352	149	14	)	)	PUNCT
dti-1352	149	15	program	program	NOUN
dti-1352	149	16	.	.	PUNCT
dti-1352	150	1	changes	change	NOUN
dti-1352	150	2	in	in	ADP
dti-1352	150	3	the	the	DET
dti-1352	150	4	creb	creb	NOUN
dti-1352	150	5	and	and	CCONJ
dti-1352	150	6	bdnf	bdnf	ADJ
dti-1352	150	7	gene	gene	NOUN
dti-1352	150	8	expression	expression	NOUN
dti-1352	150	9	levels	level	NOUN
dti-1352	150	10	were	be	AUX
dti-1352	150	11	calculated	calculate	VERB
dti-1352	150	12	in	in	ADP
dti-1352	150	13	the	the	DET
dti-1352	150	14	stress	stress	NOUN
dti-1352	150	15	-	-	PUNCT
dti-1352	150	16	exposed	expose	VERB
dti-1352	150	17	and	and	CCONJ
dti-1352	150	18	non	non	ADJ
dti-1352	150	19	-	-	ADJ
dti-1352	150	20	stressed	stressed	ADJ
dti-1352	150	21	(	(	PUNCT
dti-1352	150	22	n	n	NOUN
dti-1352	150	23	=	=	SYM
dti-1352	150	24	7	7	NUM
dti-1352	150	25	/	/	SYM
dti-1352	150	26	each	each	DET
dti-1352	150	27	group	group	NOUN
dti-1352	150	28	)	)	PUNCT
dti-1352	150	29	animal	animal	NOUN
dti-1352	150	30	groups	group	NOUN
dti-1352	150	31	.	.	PUNCT
dti-1352	151	1	the	the	DET
dti-1352	151	2	effects	effect	NOUN
dti-1352	151	3	of	of	ADP
dti-1352	151	4	agomelatine	agomelatine	NOUN
dti-1352	151	5	and	and	CCONJ
dti-1352	151	6	melatonin	melatonin	NOUN
dti-1352	151	7	(	(	PUNCT
dti-1352	151	8	n	n	NOUN
dti-1352	151	9	=	=	SYM
dti-1352	151	10	7	7	NUM
dti-1352	151	11	/	/	SYM
dti-1352	151	12	each	each	DET
dti-1352	151	13	group	group	NOUN
dti-1352	151	14	)	)	PUNCT
dti-1352	151	15	on	on	ADP
dti-1352	151	16	creb	creb	NOUN
dti-1352	151	17	and	and	CCONJ
dti-1352	151	18	bdnf	bdnf	ADJ
dti-1352	151	19	expression	expression	NOUN
dti-1352	151	20	levels	level	NOUN
dti-1352	151	21	were	be	AUX
dti-1352	151	22	also	also	ADV
dti-1352	151	23	evaluated	evaluate	VERB
dti-1352	151	24	in	in	ADP
dti-1352	151	25	the	the	DET
dti-1352	151	26	stress	stress	NOUN
dti-1352	151	27	-	-	PUNCT
dti-1352	151	28	exposed	expose	VERB
dti-1352	151	29	group	group	NOUN
dti-1352	151	30	.	.	PUNCT
dti-1352	152	1	statistics	statistic	NOUN
dti-1352	152	2	one	one	NUM
dti-1352	152	3	-	-	PUNCT
dti-1352	152	4	way	way	NOUN
dti-1352	152	5	analysis	analysis	NOUN
dti-1352	152	6	of	of	ADP
dti-1352	152	7	variance	variance	NOUN
dti-1352	152	8	(	(	PUNCT
dti-1352	152	9	anova	anova	PROPN
dti-1352	152	10	)	)	PUNCT
dti-1352	152	11	and	and	CCONJ
dti-1352	152	12	the	the	DET
dti-1352	152	13	post	post	ADJ
dti-1352	152	14	-	-	ADJ
dti-1352	152	15	hoc	hoc	X
dti-1352	152	16	tukey	tukey	NOUN
dti-1352	152	17	’s	’s	PART
dti-1352	152	18	test	test	NOUN
dti-1352	152	19	were	be	AUX
dti-1352	152	20	used	use	VERB
dti-1352	152	21	to	to	PART
dti-1352	152	22	analyze	analyze	VERB
dti-1352	152	23	the	the	DET
dti-1352	152	24	mepm	mepm	NOUN
dti-1352	152	25	,	,	PUNCT
dti-1352	152	26	mwm	mwm	NOUN
dti-1352	152	27	,	,	PUNCT
dti-1352	152	28	and	and	CCONJ
dti-1352	152	29	nor	nor	CCONJ
dti-1352	152	30	tests	test	NOUN
dti-1352	152	31	.	.	PUNCT
dti-1352	153	1	to	to	PART
dti-1352	153	2	evaluate	evaluate	VERB
dti-1352	153	3	the	the	DET
dti-1352	153	4	differences	difference	NOUN
dti-1352	153	5	among	among	ADP
dti-1352	153	6	drug	drug	NOUN
dti-1352	153	7	treatment	treatment	NOUN
dti-1352	153	8	groups	group	NOUN
dti-1352	153	9	during	during	ADP
dti-1352	153	10	the	the	DET
dti-1352	153	11	first	first	ADJ
dti-1352	153	12	and	and	CCONJ
dti-1352	153	13	second	second	ADJ
dti-1352	153	14	transfer	transfer	NOUN
dti-1352	153	15	latencies	latency	NOUN
dti-1352	153	16	in	in	ADP
dti-1352	153	17	the	the	DET
dti-1352	153	18	pa	pa	PROPN
dti-1352	153	19	test	test	NOUN
dti-1352	153	20	,	,	PUNCT
dti-1352	153	21	the	the	DET
dti-1352	153	22	kruskal	kruskal	PROPN
dti-1352	153	23	–	–	PUNCT
dti-1352	153	24	wallis	wallis	PROPN
dti-1352	153	25	non	non	ADJ
dti-1352	153	26	-	-	ADJ
dti-1352	153	27	parametric	parametric	ADJ
dti-1352	153	28	test	test	NOUN
dti-1352	153	29	was	be	AUX
dti-1352	153	30	used	use	VERB
dti-1352	153	31	followed	follow	VERB
dti-1352	153	32	by	by	ADP
dti-1352	153	33	dunn	dunn	PROPN
dti-1352	153	34	’s	’s	PART
dti-1352	153	35	post	post	ADJ
dti-1352	153	36	-	-	ADJ
dti-1352	153	37	hoc	hoc	ADJ
dti-1352	153	38	test	test	NOUN
dti-1352	153	39	.	.	PUNCT
dti-1352	154	1	data	datum	NOUN
dti-1352	154	2	are	be	AUX
dti-1352	154	3	expressed	express	VERB
dti-1352	154	4	as	as	ADP
dti-1352	154	5	the	the	DET
dti-1352	154	6	mean	mean	ADJ
dti-1352	154	7	values	value	NOUN
dti-1352	154	8	±	±	NUM
dti-1352	154	9	sem	sem	PROPN
dti-1352	154	10	.	.	PUNCT
dti-1352	155	1	p	p	X
dti-1352	155	2	,	,	PUNCT
dti-1352	155	3	0.05	0.05	NUM
dti-1352	155	4	was	be	AUX
dti-1352	155	5	accepted	accept	VERB
dti-1352	155	6	as	as	ADP
dti-1352	155	7	statistically	statistically	ADV
dti-1352	155	8	significant	significant	ADJ
dti-1352	155	9	.	.	PUNCT
dti-1352	156	1	statistical	statistical	ADJ
dti-1352	156	2	evaluation	evaluation	NOUN
dti-1352	156	3	of	of	ADP
dti-1352	156	4	bdnf	bdnf	PROPN
dti-1352	156	5	and	and	CCONJ
dti-1352	156	6	creb	creb	NOUN
dti-1352	156	7	gene	gene	NOUN
dti-1352	156	8	expressions	expression	NOUN
dti-1352	156	9	was	be	AUX
dti-1352	156	10	performed	perform	VERB
dti-1352	156	11	with	with	ADP
dti-1352	156	12	the	the	DET
dti-1352	156	13	rest	rest	NOUN
dti-1352	156	14	(	(	PUNCT
dti-1352	156	15	relative	relative	ADJ
dti-1352	156	16	expression	expression	NOUN
dti-1352	156	17	software	software	NOUN
dti-1352	156	18	tool	tool	NOUN
dti-1352	156	19	)	)	PUNCT
dti-1352	156	20	program	program	NOUN
dti-1352	156	21	.	.	PUNCT
dti-1352	157	1	http://www.la-press.com	http://www.la-press.com	X
dti-1352	157	2	agomelatin	agomelatin	PROPN
dti-1352	157	3	improves	improve	VERB
dti-1352	157	4	memory	memory	NOUN
dti-1352	157	5	in	in	ADP
dti-1352	157	6	stress	stress	NOUN
dti-1352	157	7	exposed	expose	VERB
dti-1352	157	8	mice	mouse	NOUN
dti-1352	157	9	15drug	15drug	X
dti-1352	157	10	target	target	NOUN
dti-1352	157	11	insights	insight	VERB
dti-1352	157	12	2014:8	2014:8	NUM
dti-1352	157	13	results	result	NOUN
dti-1352	157	14	effects	effect	NOUN
dti-1352	157	15	of	of	ADP
dti-1352	157	16	drugs	drug	NOUN
dti-1352	157	17	on	on	ADP
dti-1352	157	18	learning	learning	NOUN
dti-1352	157	19	and	and	CCONJ
dti-1352	157	20	memory	memory	NOUN
dti-1352	157	21	in	in	ADP
dti-1352	157	22	the	the	DET
dti-1352	157	23	pa	pa	PROPN
dti-1352	157	24	test	test	NOUN
dti-1352	157	25	.	.	PUNCT
dti-1352	158	1	there	there	PRON
dti-1352	158	2	was	be	VERB
dti-1352	158	3	no	no	DET
dti-1352	158	4	significant	significant	ADJ
dti-1352	158	5	difference	difference	NOUN
dti-1352	158	6	in	in	ADP
dti-1352	158	7	first	first	ADJ
dti-1352	158	8	day	day	NOUN
dti-1352	158	9	latency	latency	NOUN
dti-1352	158	10	among	among	ADP
dti-1352	158	11	the	the	DET
dti-1352	158	12	groups	group	NOUN
dti-1352	158	13	(	(	PUNCT
dti-1352	158	14	h	h	NOUN
dti-1352	158	15	=	=	NOUN
dti-1352	158	16	6.98	6.98	NUM
dti-1352	158	17	,	,	PUNCT
dti-1352	158	18	p	p	NOUN
dti-1352	158	19	.	.	PUNCT
dti-1352	158	20	0.05	0.05	NUM
dti-1352	158	21	,	,	PUNCT
dti-1352	158	22	figure	figure	NOUN
dti-1352	158	23	1a	1a	NOUN
dti-1352	158	24	)	)	PUNCT
dti-1352	158	25	.	.	PUNCT
dti-1352	159	1	the	the	DET
dti-1352	159	2	second	second	ADJ
dti-1352	159	3	day	day	NOUN
dti-1352	159	4	latency	latency	NOUN
dti-1352	159	5	(	(	PUNCT
dti-1352	159	6	retention	retention	NOUN
dti-1352	159	7	latency	latency	NOUN
dti-1352	159	8	)	)	PUNCT
dti-1352	159	9	significantly	significantly	ADV
dti-1352	159	10	differed	differ	VERB
dti-1352	159	11	between	between	ADP
dti-1352	159	12	the	the	DET
dti-1352	159	13	groups	group	NOUN
dti-1352	159	14	(	(	PUNCT
dti-1352	159	15	h	h	NOUN
dti-1352	159	16	=	=	NOUN
dti-1352	159	17	17.82	17.82	NUM
dti-1352	159	18	,	,	PUNCT
dti-1352	159	19	p	p	X
dti-1352	159	20	=	=	NOUN
dti-1352	159	21	0.003	0.003	NUM
dti-1352	159	22	)	)	PUNCT
dti-1352	159	23	.	.	PUNCT
dti-1352	160	1	stress	stress	NOUN
dti-1352	160	2	significantly	significantly	ADV
dti-1352	160	3	shortened	shorten	VERB
dti-1352	160	4	the	the	DET
dti-1352	160	5	retention	retention	NOUN
dti-1352	160	6	latency	latency	NOUN
dti-1352	160	7	compared	compare	VERB
dti-1352	160	8	to	to	ADP
dti-1352	160	9	the	the	DET
dti-1352	160	10	nonstressed	nonstressed	ADJ
dti-1352	160	11	control	control	NOUN
dti-1352	160	12	group	group	NOUN
dti-1352	160	13	(	(	PUNCT
dti-1352	160	14	p	p	NOUN
dti-1352	160	15	,	,	PUNCT
dti-1352	160	16	0.05	0.05	NUM
dti-1352	160	17	)	)	PUNCT
dti-1352	160	18	.	.	PUNCT
dti-1352	161	1	melatonin	melatonin	PROPN
dti-1352	161	2	prolonged	prolong	VERB
dti-1352	161	3	the	the	DET
dti-1352	161	4	retention	retention	NOUN
dti-1352	161	5	latency	latency	NOUN
dti-1352	161	6	in	in	ADP
dti-1352	161	7	stressed	stressed	ADJ
dti-1352	161	8	animals	animal	NOUN
dti-1352	161	9	(	(	PUNCT
dti-1352	161	10	p	p	NOUN
dti-1352	161	11	,	,	PUNCT
dti-1352	161	12	0.05	0.05	NUM
dti-1352	161	13	)	)	PUNCT
dti-1352	161	14	,	,	PUNCT
dti-1352	161	15	while	while	SCONJ
dti-1352	161	16	agomelatine	agomelatine	PROPN
dti-1352	161	17	had	have	VERB
dti-1352	161	18	a	a	DET
dti-1352	161	19	partial	partial	ADJ
dti-1352	161	20	but	but	CCONJ
dti-1352	161	21	statistically	statistically	ADV
dti-1352	161	22	insignificant	insignificant	ADJ
dti-1352	161	23	effect	effect	NOUN
dti-1352	161	24	(	(	PUNCT
dti-1352	161	25	fig	fig	NOUN
dti-1352	161	26	.	.	PUNCT
dti-1352	161	27	1b	1b	NUM
dti-1352	161	28	)	)	PUNCT
dti-1352	161	29	.	.	PUNCT
dti-1352	162	1	effects	effect	NOUN
dti-1352	162	2	of	of	ADP
dti-1352	162	3	drugs	drug	NOUN
dti-1352	162	4	on	on	ADP
dti-1352	162	5	learning	learning	NOUN
dti-1352	162	6	and	and	CCONJ
dti-1352	162	7	memory	memory	NOUN
dti-1352	162	8	in	in	ADP
dti-1352	162	9	the	the	DET
dti-1352	162	10	mepm	mepm	NOUN
dti-1352	162	11	test	test	NOUN
dti-1352	162	12	.	.	PUNCT
dti-1352	163	1	after	after	ADP
dti-1352	163	2	chronic	chronic	ADJ
dti-1352	163	3	injection	injection	NOUN
dti-1352	163	4	of	of	ADP
dti-1352	163	5	melatonin	melatonin	NOUN
dti-1352	163	6	(	(	PUNCT
dti-1352	163	7	10	10	NUM
dti-1352	163	8	mg	mg	NUM
dti-1352	163	9	/	/	SYM
dti-1352	163	10	kg	kg	NOUN
dti-1352	163	11	)	)	PUNCT
dti-1352	163	12	or	or	CCONJ
dti-1352	163	13	agomelatine	agomelatine	NOUN
dti-1352	163	14	(	(	PUNCT
dti-1352	163	15	10	10	NUM
dti-1352	163	16	mg	mg	NUM
dti-1352	163	17	/	/	SYM
dti-1352	163	18	kg	kg	NOUN
dti-1352	163	19	)	)	PUNCT
dti-1352	163	20	for	for	ADP
dti-1352	163	21	five	five	NUM
dti-1352	163	22	weeks	week	NOUN
dti-1352	163	23	,	,	PUNCT
dti-1352	163	24	there	there	PRON
dti-1352	163	25	was	be	VERB
dti-1352	163	26	no	no	DET
dti-1352	163	27	significant	significant	ADJ
dti-1352	163	28	difference	difference	NOUN
dti-1352	163	29	in	in	ADP
dti-1352	163	30	first	first	ADJ
dti-1352	163	31	day	day	NOUN
dti-1352	163	32	latency	latency	NOUN
dti-1352	163	33	(	(	PUNCT
dti-1352	163	34	tl1	tl1	NOUN
dti-1352	163	35	)	)	PUNCT
dti-1352	163	36	among	among	ADP
dti-1352	163	37	the	the	DET
dti-1352	163	38	groups	group	NOUN
dti-1352	163	39	[	[	X
dti-1352	163	40	f(5,35	f(5,35	ADJ
dti-1352	163	41	)	)	PUNCT
dti-1352	163	42	=	=	SYM
dti-1352	163	43	2.22	2.22	NUM
dti-1352	163	44	;	;	PUNCT
dti-1352	163	45	p	p	X
dti-1352	163	46	=	=	NOUN
dti-1352	163	47	0.07	0.07	NUM
dti-1352	163	48	,	,	PUNCT
dti-1352	163	49	figure	figure	NOUN
dti-1352	163	50	2a	2a	NUM
dti-1352	163	51	]	]	PUNCT
dti-1352	163	52	.	.	PUNCT
dti-1352	164	1	tl2	tl2	PROPN
dti-1352	164	2	(	(	PUNCT
dti-1352	164	3	latency	latency	NOUN
dti-1352	164	4	on	on	ADP
dti-1352	164	5	the	the	DET
dti-1352	164	6	second	second	ADJ
dti-1352	164	7	day	day	NOUN
dti-1352	164	8	)	)	PUNCT
dti-1352	164	9	was	be	AUX
dti-1352	164	10	significantly	significantly	ADV
dti-1352	164	11	different	different	ADJ
dti-1352	164	12	when	when	SCONJ
dti-1352	164	13	all	all	DET
dti-1352	164	14	groups	group	NOUN
dti-1352	164	15	were	be	AUX
dti-1352	164	16	compared	compare	VERB
dti-1352	164	17	[	[	X
dti-1352	164	18	f(5,35	f(5,35	ADJ
dti-1352	164	19	)	)	PUNCT
dti-1352	164	20	=	=	SYM
dti-1352	164	21	3.38	3.38	NUM
dti-1352	164	22	;	;	PUNCT
dti-1352	164	23	p	p	X
dti-1352	164	24	=	=	NOUN
dti-1352	164	25	0.01	0.01	NUM
dti-1352	164	26	,	,	PUNCT
dti-1352	164	27	figure	figure	NOUN
dti-1352	164	28	2b	2b	NOUN
dti-1352	164	29	]	]	PUNCT
dti-1352	164	30	.	.	PUNCT
dti-1352	165	1	tl2	tl2	PROPN
dti-1352	165	2	significantly	significantly	ADV
dti-1352	165	3	increased	increase	VERB
dti-1352	165	4	in	in	ADP
dti-1352	165	5	the	the	DET
dti-1352	165	6	stressed	stress	VERB
dti-1352	165	7	control	control	NOUN
dti-1352	165	8	group	group	NOUN
dti-1352	165	9	compared	compare	VERB
dti-1352	165	10	to	to	ADP
dti-1352	165	11	the	the	DET
dti-1352	165	12	non	non	ADJ
dti-1352	165	13	-	-	ADJ
dti-1352	165	14	stressed	stressed	ADJ
dti-1352	165	15	control	control	NOUN
dti-1352	165	16	group	group	NOUN
dti-1352	165	17	(	(	PUNCT
dti-1352	165	18	p	p	NOUN
dti-1352	165	19	,	,	PUNCT
dti-1352	165	20	0.05	0.05	NUM
dti-1352	165	21	)	)	PUNCT
dti-1352	165	22	,	,	PUNCT
dti-1352	165	23	and	and	CCONJ
dti-1352	165	24	this	this	DET
dti-1352	165	25	effect	effect	NOUN
dti-1352	165	26	was	be	AUX
dti-1352	165	27	significantly	significantly	ADV
dti-1352	165	28	reversed	reverse	VERB
dti-1352	165	29	by	by	ADP
dti-1352	165	30	melatonin	melatonin	NOUN
dti-1352	165	31	(	(	PUNCT
dti-1352	165	32	p	p	NOUN
dti-1352	165	33	,	,	PUNCT
dti-1352	165	34	0.05	0.05	NUM
dti-1352	165	35	)	)	PUNCT
dti-1352	165	36	,	,	PUNCT
dti-1352	165	37	while	while	SCONJ
dti-1352	165	38	agomelatine	agomelatine	PROPN
dti-1352	165	39	had	have	VERB
dti-1352	165	40	a	a	DET
dti-1352	165	41	partial	partial	ADJ
dti-1352	165	42	effect	effect	NOUN
dti-1352	165	43	but	but	CCONJ
dti-1352	165	44	failed	fail	VERB
dti-1352	165	45	to	to	PART
dti-1352	165	46	reach	reach	VERB
dti-1352	165	47	to	to	ADP
dti-1352	165	48	a	a	DET
dti-1352	165	49	statistically	statistically	ADV
dti-1352	165	50	significant	significant	ADJ
dti-1352	165	51	value	value	NOUN
dti-1352	165	52	(	(	PUNCT
dti-1352	165	53	fig	fig	NOUN
dti-1352	165	54	.	.	PUNCT
dti-1352	165	55	2b	2b	NUM
dti-1352	165	56	)	)	PUNCT
dti-1352	165	57	.	.	PUNCT
dti-1352	166	1	effects	effect	NOUN
dti-1352	166	2	of	of	ADP
dti-1352	166	3	drugs	drug	NOUN
dti-1352	166	4	on	on	ADP
dti-1352	166	5	visual	visual	ADJ
dti-1352	166	6	memory	memory	NOUN
dti-1352	166	7	in	in	ADP
dti-1352	166	8	the	the	PRON
dti-1352	166	9	nor	nor	CCONJ
dti-1352	166	10	test	test	NOUN
dti-1352	166	11	.	.	PUNCT
dti-1352	167	1	a	a	DET
dti-1352	167	2	significant	significant	ADJ
dti-1352	167	3	difference	difference	NOUN
dti-1352	167	4	was	be	AUX
dti-1352	167	5	observed	observe	VERB
dti-1352	167	6	between	between	ADP
dti-1352	167	7	the	the	DET
dti-1352	167	8	groups	group	NOUN
dti-1352	167	9	[	[	X
dti-1352	167	10	f(5,41	f(5,41	NOUN
dti-1352	167	11	)	)	PUNCT
dti-1352	167	12	=	=	NOUN
dti-1352	168	1	9.80	9.80	NUM
dti-1352	168	2	;	;	PUNCT
dti-1352	168	3	p	p	X
dti-1352	168	4	,	,	PUNCT
dti-1352	168	5	0.001	0.001	NUM
dti-1352	168	6	]	]	PUNCT
dti-1352	168	7	when	when	SCONJ
dti-1352	168	8	the	the	DET
dti-1352	168	9	effects	effect	NOUN
dti-1352	168	10	of	of	ADP
dti-1352	168	11	melatonin	melatonin	NOUN
dti-1352	168	12	or	or	CCONJ
dti-1352	168	13	agomelatine	agomelatine	NOUN
dti-1352	168	14	were	be	AUX
dti-1352	168	15	evaluated	evaluate	VERB
dti-1352	168	16	during	during	ADP
dti-1352	168	17	the	the	DET
dti-1352	168	18	retention	retention	NOUN
dti-1352	168	19	trial	trial	NOUN
dti-1352	168	20	of	of	ADP
dti-1352	168	21	the	the	PRON
dti-1352	168	22	nor	nor	CCONJ
dti-1352	168	23	test	test	NOUN
dti-1352	168	24	.	.	PUNCT
dti-1352	169	1	the	the	DET
dti-1352	169	2	ri	ri	PROPN
dti-1352	169	3	between	between	ADP
dti-1352	169	4	the	the	DET
dti-1352	169	5	stressed	stressed	ADJ
dti-1352	169	6	control	control	NOUN
dti-1352	169	7	and	and	CCONJ
dti-1352	169	8	nonstressed	nonstressed	ADJ
dti-1352	169	9	control	control	NOUN
dti-1352	169	10	mice	mouse	NOUN
dti-1352	169	11	were	be	AUX
dti-1352	169	12	significantly	significantly	ADV
dti-1352	169	13	different	different	ADJ
dti-1352	169	14	(	(	PUNCT
dti-1352	169	15	p	p	NOUN
dti-1352	169	16	,	,	PUNCT
dti-1352	169	17	0.001	0.001	NUM
dti-1352	169	18	)	)	PUNCT
dti-1352	169	19	.	.	PUNCT
dti-1352	170	1	both	both	DET
dti-1352	170	2	melatonin	melatonin	NOUN
dti-1352	170	3	and	and	CCONJ
dti-1352	170	4	agomelatine	agomelatine	PROPN
dti-1352	170	5	significantly	significantly	ADV
dti-1352	170	6	increased	increase	VERB
dti-1352	170	7	the	the	DET
dti-1352	170	8	table	table	NOUN
dti-1352	170	9	1	1	NUM
dti-1352	170	10	.	.	PUNCT
dti-1352	170	11	primary	primary	ADJ
dti-1352	170	12	sequences	sequence	NOUN
dti-1352	170	13	of	of	ADP
dti-1352	170	14	genetic	genetic	ADJ
dti-1352	170	15	studies	study	NOUN
dti-1352	170	16	.	.	PUNCT
dti-1352	171	1	gene	gene	NOUN
dti-1352	171	2	primary	primary	ADJ
dti-1352	171	3	sequence	sequence	NOUN
dti-1352	171	4	beta2	beta2	PROPN
dti-1352	171	5	microglobulin	microglobulin	PROPN
dti-1352	171	6	(	(	PUNCT
dti-1352	171	7	f	f	X
dti-1352	171	8	)	)	PUNCT
dti-1352	171	9	5	5	NUM
dti-1352	171	10	’	'	PUNCT
dti-1352	172	1	tga	tga	PROPN
dti-1352	172	2	ctt	ctt	PROPN
dti-1352	172	3	tgt	tgt	PROPN
dti-1352	172	4	cac	cac	PROPN
dti-1352	172	5	agc	agc	PROPN
dti-1352	172	6	cca	cca	PROPN
dti-1352	172	7	aga	aga	PROPN
dti-1352	172	8	ta	ta	PROPN
dti-1352	172	9	3	3	NUM
dti-1352	172	10	’	'	PUNCT
dti-1352	172	11	(	(	PUNCT
dti-1352	172	12	r	r	NOUN
dti-1352	172	13	)	)	PUNCT
dti-1352	172	14	5	5	NUM
dti-1352	172	15	’	'	PUNCT
dti-1352	172	16	aat	aat	X
dti-1352	172	17	cca	cca	PROPN
dti-1352	172	18	aat	aat	X
dti-1352	172	19	gcg	gcg	PROPN
dti-1352	172	20	gca	gca	PROPN
dti-1352	172	21	tct	tct	PROPN
dti-1352	172	22	tc	tc	PROPN
dti-1352	172	23	3	3	NUM
dti-1352	172	24	’	'	PUNCT
dti-1352	172	25	bact	bact	NOUN
dti-1352	172	26	(	(	PUNCT
dti-1352	172	27	f	f	X
dti-1352	172	28	)	)	PUNCT
dti-1352	172	29	5	5	NUM
dti-1352	172	30	’	'	PUNCT
dti-1352	172	31	agc	agc	PROPN
dti-1352	172	32	cat	cat	PROPN
dti-1352	172	33	gta	gta	PROPN
dti-1352	172	34	cgt	cgt	PROPN
dti-1352	172	35	agc	agc	PROPN
dti-1352	172	36	cat	cat	PROPN
dti-1352	172	37	cca	cca	PROPN
dti-1352	172	38	3	3	NUM
dti-1352	172	39	’	'	PUNCT
dti-1352	172	40	(	(	PUNCT
dti-1352	172	41	r	r	NOUN
dti-1352	172	42	)	)	PUNCT
dti-1352	172	43	5	5	NUM
dti-1352	172	44	’	'	PUNCT
dti-1352	172	45	tct	tct	PROPN
dti-1352	172	46	ccg	ccg	PROPN
dti-1352	172	47	gag	gag	PROPN
dti-1352	172	48	tcc	tcc	PROPN
dti-1352	172	49	atc	atc	PROPN
dti-1352	172	50	aca	aca	PROPN
dti-1352	172	51	atg3	atg3	PROPN
dti-1352	172	52	’	'	PUNCT
dti-1352	172	53	creb	creb	NOUN
dti-1352	172	54	(	(	PUNCT
dti-1352	172	55	f	f	X
dti-1352	172	56	)	)	PUNCT
dti-1352	172	57	5	5	NUM
dti-1352	172	58	’	'	PUNCT
dti-1352	172	59	agc	agc	PROPN
dti-1352	172	60	tgg	tgg	PROPN
dti-1352	172	61	cct	cct	PROPN
dti-1352	172	62	gtc	gtc	PROPN
dti-1352	172	63	cca	cca	PROPN
dti-1352	172	64	ctg	ctg	PROPN
dti-1352	172	65	ct	ct	PROPN
dti-1352	172	66	3	3	NUM
dti-1352	172	67	’	'	PUNCT
dti-1352	172	68	(	(	PUNCT
dti-1352	172	69	r	r	NOUN
dti-1352	172	70	)	)	PUNCT
dti-1352	172	71	5	5	NUM
dti-1352	172	72	’	'	PUNCT
dti-1352	172	73	acc	acc	PROPN
dti-1352	172	74	att	att	PROPN
dti-1352	172	75	ctg	ctg	PROPN
dti-1352	172	76	aac	aac	NOUN
dti-1352	172	77	aca	aca	PROPN
dti-1352	172	78	aag	aag	PROPN
dti-1352	172	79	cag	cag	PROPN
dti-1352	172	80	cca3	cca3	PROPN
dti-1352	172	81	’	'	PUNCT
dti-1352	172	82	bdnf	bdnf	PROPN
dti-1352	172	83	(	(	PUNCT
dti-1352	172	84	f	f	X
dti-1352	172	85	)	)	PUNCT
dti-1352	172	86	5	5	NUM
dti-1352	172	87	’	'	PUNCT
dti-1352	172	88	gcc	gcc	NOUN
dti-1352	172	89	caa	caa	NOUN
dti-1352	172	90	cga	cga	PROPN
dti-1352	172	91	aga	aga	PROPN
dti-1352	172	92	aaa	aaa	PROPN
dti-1352	172	93	cca	cca	PROPN
dti-1352	173	1	taa	taa	X
dti-1352	173	2	3	3	NUM
dti-1352	173	3	’	'	PUNCT
dti-1352	173	4	(	(	PUNCT
dti-1352	173	5	r	r	NOUN
dti-1352	173	6	)	)	PUNCT
dti-1352	173	7	5	5	NUM
dti-1352	173	8	’	'	PUNCT
dti-1352	173	9	gga	gga	PROPN
dti-1352	173	10	ggc	ggc	PROPN
dti-1352	173	11	tcc	tcc	PROPN
dti-1352	173	12	aaa	aaa	PROPN
dti-1352	173	13	ggc	ggc	PROPN
dti-1352	173	14	act	act	PROPN
dti-1352	173	15	t	t	PROPN
dti-1352	173	16	3	3	NUM
dti-1352	173	17	’	'	PUNCT
dti-1352	173	18	pa	pa	PROPN
dti-1352	173	19	test	test	NOUN
dti-1352	173	20	0	0	NUM
dti-1352	173	21	10	10	NUM
dti-1352	173	22	20	20	NUM
dti-1352	173	23	30	30	NUM
dti-1352	173	24	40	40	NUM
dti-1352	173	25	50	50	NUM
dti-1352	173	26	60	60	NUM
dti-1352	173	27	70	70	NUM
dti-1352	173	28	drugs	drug	NOUN
dti-1352	173	29	f	f	PROPN
dti-1352	173	30	ir	ir	PROPN
dti-1352	173	31	st	st	PROPN
dti-1352	173	32	d	d	PROPN
dti-1352	173	33	ay	ay	PROPN
dti-1352	173	34	l	l	NOUN
dti-1352	173	35	at	at	ADP
dti-1352	173	36	en	en	PROPN
dti-1352	173	37	cy	cy	PROPN
dti-1352	173	38	nc	nc	PROPN
dti-1352	173	39	nm	nm	PROPN
dti-1352	173	40	na	na	ADP
dti-1352	173	41	sc	sc	PROPN
dti-1352	173	42	sm	sm	PROPN
dti-1352	173	43	sa	sa	PROPN
dti-1352	173	44	pa	pa	PROPN
dti-1352	173	45	test	test	PROPN
dti-1352	173	46	0	0	NUM
dti-1352	173	47	10	10	NUM
dti-1352	173	48	20	20	NUM
dti-1352	173	49	30	30	NUM
dti-1352	173	50	40	40	NUM
dti-1352	173	51	50	50	NUM
dti-1352	173	52	60	60	NUM
dti-1352	173	53	70	70	NUM
dti-1352	173	54	80	80	NUM
dti-1352	173	55	90	90	NUM
dti-1352	173	56	drugs	drug	NOUN
dti-1352	173	57	r	r	VERB
dti-1352	173	58	et	et	NOUN
dti-1352	173	59	en	en	ADP
dti-1352	173	60	ti	ti	X
dti-1352	173	61	o	o	PROPN
dti-1352	173	62	n	n	PRON
dti-1352	173	63	l	l	NOUN
dti-1352	173	64	at	at	ADP
dti-1352	173	65	en	en	PROPN
dti-1352	173	66	cy	cy	PROPN
dti-1352	173	67	nc	nc	PROPN
dti-1352	173	68	nm	nm	PROPN
dti-1352	173	69	na	na	ADP
dti-1352	173	70	sc	sc	PROPN
dti-1352	174	1	sm	sm	INTJ
dti-1352	174	2	sa	sa	PROPN
dti-1352	175	1	a	a	DET
dti-1352	175	2	b	b	PROPN
dti-1352	175	3	figure	figure	NOUN
dti-1352	175	4	1	1	NUM
dti-1352	175	5	.	.	PUNCT
dti-1352	175	6	effects	effect	NOUN
dti-1352	175	7	of	of	ADP
dti-1352	175	8	melatonin	melatonin	NOUN
dti-1352	175	9	(	(	PUNCT
dti-1352	175	10	10	10	NUM
dti-1352	175	11	mg	mg	NUM
dti-1352	175	12	/	/	SYM
dti-1352	175	13	kg	kg	NOUN
dti-1352	175	14	)	)	PUNCT
dti-1352	175	15	or	or	CCONJ
dti-1352	175	16	agomelatine	agomelatine	NOUN
dti-1352	175	17	(	(	PUNCT
dti-1352	175	18	10	10	NUM
dti-1352	175	19	mg	mg	NUM
dti-1352	175	20	/	/	SYM
dti-1352	175	21	kg	kg	NOUN
dti-1352	175	22	)	)	PUNCT
dti-1352	175	23	on	on	ADP
dti-1352	175	24	(	(	PUNCT
dti-1352	175	25	a	a	X
dti-1352	175	26	)	)	PUNCT
dti-1352	175	27	first	first	ADJ
dti-1352	175	28	day	day	NOUN
dti-1352	175	29	latency	latency	NOUN
dti-1352	175	30	and	and	CCONJ
dti-1352	175	31	(	(	PUNCT
dti-1352	175	32	b	b	NOUN
dti-1352	175	33	)	)	PUNCT
dti-1352	175	34	retention	retention	NOUN
dti-1352	175	35	latency	latency	NOUN
dti-1352	175	36	in	in	ADP
dti-1352	175	37	the	the	DET
dti-1352	175	38	passive	passive	ADJ
dti-1352	175	39	avoidance	avoidance	NOUN
dti-1352	175	40	test	test	NOUN
dti-1352	175	41	in	in	ADP
dti-1352	175	42	mice	mouse	NOUN
dti-1352	175	43	.	.	PUNCT
dti-1352	176	1	notes	note	NOUN
dti-1352	176	2	:	:	PUNCT
dti-1352	176	3	the	the	DET
dti-1352	176	4	data	datum	NOUN
dti-1352	176	5	are	be	AUX
dti-1352	176	6	expressed	express	VERB
dti-1352	176	7	as	as	ADP
dti-1352	176	8	the	the	DET
dti-1352	176	9	mean	mean	PROPN
dti-1352	176	10	±	±	NUM
dti-1352	176	11	sem	sem	NOUN
dti-1352	176	12	values	value	NOUN
dti-1352	176	13	.	.	PUNCT
dti-1352	177	1	*	*	PUNCT
dti-1352	177	2	p	p	NOUN
dti-1352	177	3	,	,	PUNCT
dti-1352	177	4	0.05	0.05	NUM
dti-1352	177	5	vs.	vs.	ADP
dti-1352	177	6	non	non	ADJ
dti-1352	177	7	-	-	ADJ
dti-1352	177	8	stressed	stressed	ADJ
dti-1352	177	9	control	control	NOUN
dti-1352	177	10	group	group	NOUN
dti-1352	177	11	.	.	PUNCT
dti-1352	178	1	#	#	SYM
dti-1352	178	2	p	p	NOUN
dti-1352	178	3	,	,	PUNCT
dti-1352	178	4	0.05	0.05	NUM
dti-1352	178	5	vs.	vs.	ADP
dti-1352	178	6	stressed	stress	VERB
dti-1352	178	7	control	control	PROPN
dti-1352	178	8	group	group	PROPN
dti-1352	178	9	.	.	PUNCT
dti-1352	179	1	http://www.la-press.com	http://www.la-press.com	X
dti-1352	180	1	gumuslu	gumuslu	PROPN
dti-1352	180	2	et	et	PROPN
dti-1352	180	3	al	al	PROPN
dti-1352	180	4	16	16	NUM
dti-1352	180	5	drug	drug	NOUN
dti-1352	180	6	target	target	NOUN
dti-1352	180	7	insights	insight	VERB
dti-1352	180	8	2014:8	2014:8	NUM
dti-1352	180	9	mepm	mepm	NOUN
dti-1352	180	10	test	test	NOUN
dti-1352	180	11	0	0	NUM
dti-1352	180	12	10	10	NUM
dti-1352	180	13	20	20	NUM
dti-1352	180	14	30	30	NUM
dti-1352	180	15	40	40	NUM
dti-1352	180	16	50	50	NUM
dti-1352	180	17	60	60	NUM
dti-1352	180	18	70	70	NUM
dti-1352	180	19	drugs	drug	NOUN
dti-1352	180	20	t	t	NOUN
dti-1352	180	21	l	l	PROPN
dti-1352	180	22	-1	-1	PROPN
dti-1352	180	23	nc	nc	PROPN
dti-1352	180	24	nm	nm	PROPN
dti-1352	180	25	na	na	PROPN
dti-1352	180	26	sc	sc	PROPN
dti-1352	180	27	sm	sm	PROPN
dti-1352	180	28	sa	sa	PROPN
dti-1352	180	29	mepm	mepm	PROPN
dti-1352	180	30	test	test	NOUN
dti-1352	180	31	0	0	NUM
dti-1352	180	32	2	2	NUM
dti-1352	180	33	4	4	NUM
dti-1352	180	34	6	6	NUM
dti-1352	180	35	8	8	NUM
dti-1352	180	36	10	10	NUM
dti-1352	180	37	12	12	NUM
dti-1352	180	38	14	14	NUM
dti-1352	180	39	drugs	drug	NOUN
dti-1352	180	40	t	t	NOUN
dti-1352	180	41	l	l	NOUN
dti-1352	180	42	-2	-2	PROPN
dti-1352	180	43	nc	nc	PROPN
dti-1352	180	44	nm	nm	ADV
dti-1352	180	45	na	na	ADP
dti-1352	180	46	sc	sc	PROPN
dti-1352	181	1	sm	sm	INTJ
dti-1352	181	2	sa	sa	PROPN
dti-1352	182	1	a	a	DET
dti-1352	182	2	b	b	PROPN
dti-1352	182	3	figure	figure	NOUN
dti-1352	182	4	2	2	NUM
dti-1352	182	5	.	.	PUNCT
dti-1352	182	6	effects	effect	NOUN
dti-1352	182	7	of	of	ADP
dti-1352	182	8	melatonin	melatonin	NOUN
dti-1352	182	9	(	(	PUNCT
dti-1352	182	10	10	10	NUM
dti-1352	182	11	mg	mg	NUM
dti-1352	182	12	/	/	SYM
dti-1352	182	13	kg	kg	NOUN
dti-1352	182	14	)	)	PUNCT
dti-1352	182	15	or	or	CCONJ
dti-1352	182	16	agomelatine	agomelatine	NOUN
dti-1352	182	17	(	(	PUNCT
dti-1352	182	18	10	10	NUM
dti-1352	182	19	mg	mg	NUM
dti-1352	182	20	/	/	SYM
dti-1352	182	21	kg	kg	NOUN
dti-1352	182	22	)	)	PUNCT
dti-1352	182	23	on	on	ADP
dti-1352	182	24	(	(	PUNCT
dti-1352	182	25	a	a	DET
dti-1352	182	26	)	)	PUNCT
dti-1352	182	27	transfer	transfer	NOUN
dti-1352	182	28	latency	latency	NOUN
dti-1352	182	29	on	on	ADP
dti-1352	182	30	the	the	DET
dti-1352	182	31	first	first	ADJ
dti-1352	182	32	day	day	NOUN
dti-1352	182	33	(	(	PUNCT
dti-1352	182	34	b	b	NOUN
dti-1352	182	35	)	)	PUNCT
dti-1352	182	36	transfer	transfer	NOUN
dti-1352	182	37	latency	latency	NOUN
dti-1352	182	38	on	on	ADP
dti-1352	182	39	the	the	DET
dti-1352	182	40	second	second	ADJ
dti-1352	182	41	day	day	NOUN
dti-1352	182	42	.	.	PUNCT
dti-1352	183	1	notes	note	VERB
dti-1352	183	2	:	:	PUNCT
dti-1352	183	3	the	the	DET
dti-1352	183	4	data	datum	NOUN
dti-1352	183	5	are	be	AUX
dti-1352	183	6	expressed	express	VERB
dti-1352	183	7	as	as	ADP
dti-1352	183	8	mean	mean	PROPN
dti-1352	183	9	±	±	NUM
dti-1352	183	10	sem	sem	NOUN
dti-1352	183	11	values	value	NOUN
dti-1352	183	12	.	.	PUNCT
dti-1352	184	1	*	*	PUNCT
dti-1352	184	2	p	p	NOUN
dti-1352	184	3	,	,	PUNCT
dti-1352	184	4	0.05	0.05	NUM
dti-1352	184	5	vs.	vs.	ADP
dti-1352	184	6	non	non	ADJ
dti-1352	184	7	-	-	ADJ
dti-1352	184	8	stressed	stressed	ADJ
dti-1352	184	9	control	control	NOUN
dti-1352	184	10	group	group	NOUN
dti-1352	184	11	.	.	PUNCT
dti-1352	185	1	#	#	SYM
dti-1352	185	2	p	p	NOUN
dti-1352	185	3	,	,	PUNCT
dti-1352	185	4	0.05	0.05	NUM
dti-1352	185	5	vs.	vs.	ADP
dti-1352	185	6	stressed	stress	VERB
dti-1352	185	7	control	control	NOUN
dti-1352	185	8	group	group	NOUN
dti-1352	185	9	.	.	PUNCT
dti-1352	186	1	nor	nor	CCONJ
dti-1352	186	2	test	test	VERB
dti-1352	186	3	0	0	NUM
dti-1352	186	4	10	10	NUM
dti-1352	186	5	20	20	NUM
dti-1352	186	6	30	30	NUM
dti-1352	186	7	40	40	NUM
dti-1352	186	8	50	50	NUM
dti-1352	186	9	60	60	NUM
dti-1352	186	10	70	70	NUM
dti-1352	186	11	80	80	NUM
dti-1352	186	12	90	90	NUM
dti-1352	186	13	drugs	drug	NOUN
dti-1352	186	14	r	r	NOUN
dti-1352	186	15	at	at	ADP
dti-1352	186	16	io	io	X
dti-1352	186	17	i	i	PROPN
dti-1352	186	18	n	n	PROPN
dti-1352	186	19	d	d	X
dti-1352	186	20	ex	ex	X
dti-1352	186	21	nc	nc	PROPN
dti-1352	186	22	nm	nm	ADV
dti-1352	186	23	na	na	ADP
dti-1352	186	24	sc	sc	PROPN
dti-1352	186	25	sm	sm	PROPN
dti-1352	186	26	sa	sa	PROPN
dti-1352	186	27	figure	figure	NOUN
dti-1352	186	28	3	3	NUM
dti-1352	186	29	.	.	PUNCT
dti-1352	186	30	effect	effect	NOUN
dti-1352	186	31	of	of	ADP
dti-1352	186	32	melatonin	melatonin	NOUN
dti-1352	186	33	(	(	PUNCT
dti-1352	186	34	10	10	NUM
dti-1352	186	35	mg	mg	NUM
dti-1352	186	36	/	/	SYM
dti-1352	186	37	kg	kg	NOUN
dti-1352	186	38	)	)	PUNCT
dti-1352	186	39	or	or	CCONJ
dti-1352	186	40	agomelatine	agomelatine	NOUN
dti-1352	186	41	(	(	PUNCT
dti-1352	186	42	10	10	NUM
dti-1352	186	43	mg	mg	NUM
dti-1352	186	44	/	/	SYM
dti-1352	186	45	kg	kg	NOUN
dti-1352	186	46	)	)	PUNCT
dti-1352	186	47	on	on	ADP
dti-1352	186	48	the	the	DET
dti-1352	186	49	ri	ri	PROPN
dti-1352	186	50	in	in	ADP
dti-1352	186	51	the	the	DET
dti-1352	186	52	novel	novel	ADJ
dti-1352	186	53	object	object	NOUN
dti-1352	186	54	recognition	recognition	NOUN
dti-1352	186	55	test	test	NOUN
dti-1352	186	56	.	.	PUNCT
dti-1352	187	1	notes	note	VERB
dti-1352	187	2	:	:	PUNCT
dti-1352	187	3	the	the	DET
dti-1352	187	4	data	datum	NOUN
dti-1352	187	5	are	be	AUX
dti-1352	187	6	expressed	express	VERB
dti-1352	187	7	as	as	ADP
dti-1352	187	8	mean	mean	PROPN
dti-1352	187	9	±	±	NUM
dti-1352	187	10	sem	sem	NOUN
dti-1352	187	11	values	value	NOUN
dti-1352	187	12	.	.	PUNCT
dti-1352	188	1	*	*	PUNCT
dti-1352	188	2	p	p	NOUN
dti-1352	188	3	,	,	PUNCT
dti-1352	188	4	0.001	0.001	NUM
dti-1352	188	5	vs.	vs.	ADP
dti-1352	188	6	non	non	ADJ
dti-1352	188	7	-	-	ADJ
dti-1352	188	8	stressed	stressed	ADJ
dti-1352	188	9	control	control	NOUN
dti-1352	188	10	group	group	NOUN
dti-1352	188	11	.	.	PUNCT
dti-1352	189	1	#	#	SYM
dti-1352	189	2	p	p	NOUN
dti-1352	189	3	,	,	PUNCT
dti-1352	189	4	0.001	0.001	NUM
dti-1352	189	5	vs.	vs.	ADP
dti-1352	189	6	stressed	stress	VERB
dti-1352	189	7	control	control	PROPN
dti-1352	189	8	group	group	PROPN
dti-1352	189	9	.	.	PUNCT
dti-1352	190	1	ri	ri	PROPN
dti-1352	190	2	compared	compare	VERB
dti-1352	190	3	to	to	ADP
dti-1352	190	4	stress	stress	NOUN
dti-1352	190	5	-	-	PUNCT
dti-1352	190	6	exposed	expose	VERB
dti-1352	190	7	control	control	NOUN
dti-1352	190	8	mice	mouse	NOUN
dti-1352	190	9	(	(	PUNCT
dti-1352	190	10	p	p	NOUN
dti-1352	190	11	,	,	PUNCT
dti-1352	190	12	0.001	0.001	NUM
dti-1352	190	13	)	)	PUNCT
dti-1352	190	14	(	(	PUNCT
dti-1352	190	15	fig	fig	NOUN
dti-1352	190	16	.	.	PUNCT
dti-1352	191	1	3	3	NUM
dti-1352	191	2	)	)	PUNCT
dti-1352	191	3	.	.	PUNCT
dti-1352	192	1	effects	effect	NOUN
dti-1352	192	2	of	of	ADP
dti-1352	192	3	drugs	drug	NOUN
dti-1352	192	4	on	on	ADP
dti-1352	192	5	learning	learning	NOUN
dti-1352	192	6	and	and	CCONJ
dti-1352	192	7	memory	memory	NOUN
dti-1352	192	8	in	in	ADP
dti-1352	192	9	the	the	DET
dti-1352	192	10	mwm	mwm	NOUN
dti-1352	192	11	test	test	NOUN
dti-1352	192	12	.	.	PUNCT
dti-1352	193	1	there	there	PRON
dti-1352	193	2	was	be	VERB
dti-1352	193	3	a	a	DET
dti-1352	193	4	significant	significant	ADJ
dti-1352	193	5	difference	difference	NOUN
dti-1352	193	6	in	in	ADP
dti-1352	193	7	escape	escape	NOUN
dti-1352	193	8	latency	latency	NOUN
dti-1352	193	9	in	in	ADP
dti-1352	193	10	all	all	DET
dti-1352	193	11	sessions	session	NOUN
dti-1352	193	12	during	during	ADP
dti-1352	193	13	the	the	DET
dti-1352	193	14	evaluation	evaluation	NOUN
dti-1352	193	15	of	of	ADP
dti-1352	193	16	drug	drug	NOUN
dti-1352	193	17	groups	group	NOUN
dti-1352	193	18	[	[	X
dti-1352	193	19	f(5,41	f(5,41	NOUN
dti-1352	193	20	)	)	PUNCT
dti-1352	193	21	=	=	SYM
dti-1352	193	22	8.22	8.22	NUM
dti-1352	193	23	,	,	PUNCT
dti-1352	193	24	p	p	NOUN
dti-1352	193	25	,	,	PUNCT
dti-1352	193	26	0.001	0.001	NUM
dti-1352	193	27	;	;	PUNCT
dti-1352	193	28	f(5,41	f(5,41	X
dti-1352	193	29	)	)	PUNCT
dti-1352	193	30	=	=	SYM
dti-1352	193	31	10.77	10.77	NUM
dti-1352	193	32	,	,	PUNCT
dti-1352	193	33	p	p	NOUN
dti-1352	193	34	,	,	PUNCT
dti-1352	193	35	0.001	0.001	NUM
dti-1352	193	36	;	;	PUNCT
dti-1352	193	37	f(5,41	f(5,41	X
dti-1352	193	38	)	)	PUNCT
dti-1352	193	39	=	=	NOUN
dti-1352	193	40	8.93	8.93	NUM
dti-1352	193	41	,	,	PUNCT
dti-1352	193	42	p	p	NOUN
dti-1352	193	43	,	,	PUNCT
dti-1352	193	44	0.001	0.001	NUM
dti-1352	193	45	;	;	PUNCT
dti-1352	193	46	f(5,41	f(5,41	X
dti-1352	193	47	)	)	PUNCT
dti-1352	193	48	=	=	NOUN
dti-1352	193	49	12.40	12.40	NUM
dti-1352	193	50	,	,	PUNCT
dti-1352	193	51	p	p	NOUN
dti-1352	193	52	,	,	PUNCT
dti-1352	193	53	0.001	0.001	NUM
dti-1352	193	54	;	;	PUNCT
dti-1352	193	55	f(5,41	f(5,41	PROPN
dti-1352	193	56	)	)	PUNCT
dti-1352	193	57	=	=	SYM
dti-1352	193	58	10.32	10.32	NUM
dti-1352	193	59	,	,	PUNCT
dti-1352	193	60	p	p	NOUN
dti-1352	193	61	,	,	PUNCT
dti-1352	193	62	0.001	0.001	NUM
dti-1352	193	63	,	,	PUNCT
dti-1352	193	64	respectively	respectively	ADV
dti-1352	193	65	;	;	PUNCT
dti-1352	193	66	figure	figure	NOUN
dti-1352	193	67	4a	4a	NOUN
dti-1352	193	68	]	]	PUNCT
dti-1352	193	69	.	.	PUNCT
dti-1352	194	1	stress	stress	NOUN
dti-1352	194	2	significantly	significantly	ADV
dti-1352	194	3	increased	increase	VERB
dti-1352	194	4	the	the	DET
dti-1352	194	5	escape	escape	NOUN
dti-1352	194	6	latency	latency	NOUN
dti-1352	194	7	during	during	ADP
dti-1352	194	8	all	all	DET
dti-1352	194	9	sessions	session	NOUN
dti-1352	194	10	(	(	PUNCT
dti-1352	194	11	p	p	NOUN
dti-1352	194	12	,	,	PUNCT
dti-1352	194	13	0.001	0.001	NUM
dti-1352	194	14	)	)	PUNCT
dti-1352	194	15	in	in	ADP
dti-1352	194	16	control	control	NOUN
dti-1352	194	17	animals	animal	NOUN
dti-1352	194	18	,	,	PUNCT
dti-1352	194	19	whereas	whereas	SCONJ
dti-1352	194	20	both	both	DET
dti-1352	194	21	melatonin	melatonin	NOUN
dti-1352	194	22	and	and	CCONJ
dti-1352	194	23	agomelatine	agomelatine	PROPN
dti-1352	194	24	http://www.la-press.com	http://www.la-press.com	X
dti-1352	194	25	agomelatin	agomelatin	PROPN
dti-1352	194	26	improves	improve	VERB
dti-1352	194	27	memory	memory	NOUN
dti-1352	194	28	in	in	ADP
dti-1352	194	29	stress	stress	NOUN
dti-1352	194	30	exposed	expose	VERB
dti-1352	194	31	mice	mouse	NOUN
dti-1352	194	32	17drug	17drug	PUNCT
dti-1352	194	33	target	target	NOUN
dti-1352	194	34	insights	insight	VERB
dti-1352	194	35	2014:8	2014:8	NUM
dti-1352	194	36	mwm	mwm	NOUN
dti-1352	194	37	test	test	NOUN
dti-1352	194	38	0	0	NUM
dti-1352	194	39	20	20	NUM
dti-1352	194	40	40	40	NUM
dti-1352	194	41	60	60	NUM
dti-1352	194	42	80	80	NUM
dti-1352	194	43	100	100	NUM
dti-1352	194	44	120	120	NUM
dti-1352	194	45	140	140	NUM
dti-1352	194	46	160	160	NUM
dti-1352	194	47	sessions	session	NOUN
dti-1352	195	1	nc	nc	VERB
dti-1352	195	2	nm	nm	PROPN
dti-1352	195	3	na	na	ADP
dti-1352	195	4	sc	sc	PROPN
dti-1352	195	5	sm	sm	PROPN
dti-1352	195	6	sa	sa	PROPN
dti-1352	195	7	mwm	mwm	NOUN
dti-1352	195	8	test	test	NOUN
dti-1352	195	9	0	0	NUM
dti-1352	195	10	5	5	NUM
dti-1352	195	11	10	10	NUM
dti-1352	195	12	15	15	NUM
dti-1352	195	13	20	20	NUM
dti-1352	195	14	25	25	NUM
dti-1352	195	15	30	30	NUM
dti-1352	195	16	35	35	NUM
dti-1352	195	17	40	40	NUM
dti-1352	195	18	drugs	drug	NOUN
dti-1352	195	19	nc	nc	VERB
dti-1352	195	20	nm	nm	ADV
dti-1352	195	21	na	na	ADP
dti-1352	195	22	sc	sc	PROPN
dti-1352	195	23	sm	sm	PROPN
dti-1352	195	24	sa	sa	PROPN
dti-1352	195	25	nc	nc	PROPN
dti-1352	195	26	nm	nm	PROPN
dti-1352	195	27	na	na	ADP
dti-1352	195	28	sc	sc	PROPN
dti-1352	195	29	sm	sm	PROPN
dti-1352	195	30	sa	sa	PROPN
dti-1352	195	31	nc	nc	PROPN
dti-1352	195	32	nm	nm	PROPN
dti-1352	195	33	na	na	ADP
dti-1352	195	34	sc	sc	PROPN
dti-1352	195	35	sm	sm	PROPN
dti-1352	195	36	sa	sa	PROPN
dti-1352	195	37	mwm	mwm	NOUN
dti-1352	195	38	test	test	NOUN
dti-1352	195	39	0	0	NUM
dti-1352	195	40	5	5	NUM
dti-1352	195	41	10	10	NUM
dti-1352	195	42	15	15	NUM
dti-1352	195	43	20	20	NUM
dti-1352	195	44	25	25	NUM
dti-1352	195	45	30	30	NUM
dti-1352	195	46	35	35	NUM
dti-1352	195	47	40	40	NUM
dti-1352	195	48	drugs	drug	NOUN
dti-1352	195	49	mwm	mwm	NOUN
dti-1352	195	50	test	test	NOUN
dti-1352	195	51	0	0	NUM
dti-1352	195	52	5	5	NUM
dti-1352	195	53	10	10	NUM
dti-1352	195	54	15	15	NUM
dti-1352	195	55	20	20	NUM
dti-1352	195	56	25	25	NUM
dti-1352	195	57	drugs	drug	NOUN
dti-1352	195	58	e	e	X
dti-1352	195	59	sc	sc	PROPN
dti-1352	195	60	ap	ap	PROPN
dti-1352	195	61	e	e	PROPN
dti-1352	195	62	la	la	PROPN
dti-1352	195	63	te	te	PROPN
dti-1352	195	64	n	n	X
dti-1352	195	65	cy	cy	PROPN
dti-1352	195	66	(	(	PUNCT
dti-1352	195	67	s	s	PROPN
dti-1352	195	68	)	)	PUNCT
dti-1352	195	69	t	t	NOUN
dti-1352	195	70	i	i	PRON
dti-1352	195	71	m	m	VERB
dti-1352	195	72	e	e	VERB
dti-1352	195	73	sp	sp	ADP
dti-1352	195	74	en	en	X
dti-1352	195	75	t	t	PROPN
dti-1352	195	76	in	in	ADP
dti-1352	195	77	t	t	PROPN
dti-1352	195	78	ar	ar	PROPN
dti-1352	195	79	g	g	PROPN
dti-1352	195	80	et	et	PROPN
dti-1352	195	81	q	q	PROPN
dti-1352	195	82	u	u	PROPN
dti-1352	195	83	ad	ad	NOUN
dti-1352	195	84	ra	ra	PROPN
dti-1352	195	85	n	n	PRON
dti-1352	195	86	t	t	PROPN
dti-1352	195	87	in	in	ADP
dti-1352	195	88	p	p	PROPN
dti-1352	195	89	ro	ro	PROPN
dti-1352	195	90	b	b	PROPN
dti-1352	195	91	e	e	PROPN
dti-1352	195	92	tr	tr	PROPN
dti-1352	195	93	ia	ia	PROPN
dti-1352	195	94	l	l	NOUN
dti-1352	195	95	(	(	PUNCT
dti-1352	195	96	s	s	X
dti-1352	195	97	)	)	PUNCT
dti-1352	195	98	m	m	VERB
dti-1352	195	99	ea	ea	NOUN
dti-1352	196	1	n	n	NUM
dti-1352	196	2	d	d	NOUN
dti-1352	196	3	is	be	AUX
dti-1352	196	4	ta	ta	PROPN
dti-1352	196	5	n	n	NUM
dti-1352	196	6	ce	ce	PROPN
dti-1352	196	7	t	t	NOUN
dti-1352	197	1	o	o	X
dti-1352	198	1	p	p	X
dti-1352	199	1	la	la	INTJ
dti-1352	200	1	tf	tf	X
dti-1352	200	2	o	o	PROPN
dti-1352	200	3	rm	rm	NOUN
dti-1352	200	4	in	in	ADP
dti-1352	200	5	p	p	PROPN
dti-1352	200	6	ro	ro	PROPN
dti-1352	200	7	b	b	PROPN
dti-1352	200	8	e	e	PROPN
dti-1352	200	9	tr	tr	PROPN
dti-1352	200	10	ia	ia	PROPN
dti-1352	200	11	l	l	NOUN
dti-1352	200	12	(	(	PUNCT
dti-1352	200	13	cm	cm	NOUN
dti-1352	200	14	)	)	PUNCT
dti-1352	200	15	s	s	PART
dti-1352	200	16	p	p	X
dti-1352	200	17	ee	ee	X
dti-1352	200	18	d	d	PROPN
dti-1352	200	19	(	(	PUNCT
dti-1352	200	20	cm	cm	PROPN
dti-1352	200	21	/s	/s	PUNCT
dti-1352	200	22	)	)	PUNCT
dti-1352	201	1	a	a	DET
dti-1352	201	2	b	b	NOUN
dti-1352	201	3	c	c	NOUN
dti-1352	201	4	d	d	NOUN
dti-1352	201	5	fam	fam	NOUN
dti-1352	201	6	ses	se	VERB
dti-1352	201	7	1st	1st	PROPN
dti-1352	201	8	ses	se	NOUN
dti-1352	201	9	2nd	2nd	ADJ
dti-1352	201	10	ses	se	NOUN
dti-1352	201	11	3rd	3rd	PROPN
dti-1352	201	12	ses	se	NOUN
dti-1352	201	13	4th	4th	ADJ
dti-1352	201	14	ses	se	NOUN
dti-1352	201	15	figure	figure	NOUN
dti-1352	201	16	4	4	NUM
dti-1352	201	17	.	.	PUNCT
dti-1352	202	1	effects	effect	NOUN
dti-1352	202	2	of	of	ADP
dti-1352	202	3	melatonin	melatonin	NOUN
dti-1352	202	4	(	(	PUNCT
dti-1352	202	5	10	10	NUM
dti-1352	202	6	mg	mg	NUM
dti-1352	202	7	/	/	SYM
dti-1352	202	8	kg	kg	NOUN
dti-1352	202	9	)	)	PUNCT
dti-1352	202	10	or	or	CCONJ
dti-1352	202	11	agomelatine	agomelatine	NOUN
dti-1352	202	12	(	(	PUNCT
dti-1352	202	13	10	10	NUM
dti-1352	202	14	mg	mg	NUM
dti-1352	202	15	/	/	SYM
dti-1352	202	16	kg	kg	NOUN
dti-1352	202	17	)	)	PUNCT
dti-1352	202	18	on	on	ADP
dti-1352	202	19	(	(	PUNCT
dti-1352	202	20	a	a	PRON
dti-1352	202	21	)	)	PUNCT
dti-1352	202	22	escape	escape	NOUN
dti-1352	202	23	latency	latency	NOUN
dti-1352	202	24	,	,	PUNCT
dti-1352	202	25	(	(	PUNCT
dti-1352	202	26	b	b	X
dti-1352	202	27	)	)	PUNCT
dti-1352	202	28	the	the	DET
dti-1352	202	29	time	time	NOUN
dti-1352	202	30	spent	spend	VERB
dti-1352	202	31	in	in	ADP
dti-1352	202	32	escape	escape	NOUN
dti-1352	202	33	platform	platform	NOUN
dti-1352	202	34	quadrant	quadrant	NOUN
dti-1352	202	35	,	,	PUNCT
dti-1352	202	36	(	(	PUNCT
dti-1352	202	37	c	c	X
dti-1352	202	38	)	)	PUNCT
dti-1352	202	39	mean	mean	ADJ
dti-1352	202	40	distance	distance	NOUN
dti-1352	202	41	to	to	ADP
dti-1352	202	42	platform	platform	NOUN
dti-1352	202	43	,	,	PUNCT
dti-1352	202	44	and	and	CCONJ
dti-1352	202	45	(	(	PUNCT
dti-1352	202	46	d	d	X
dti-1352	202	47	)	)	PUNCT
dti-1352	202	48	swim	swim	NOUN
dti-1352	202	49	speed	speed	NOUN
dti-1352	202	50	in	in	ADP
dti-1352	202	51	the	the	DET
dti-1352	202	52	probe	probe	NOUN
dti-1352	202	53	trial	trial	NOUN
dti-1352	202	54	(	(	PUNCT
dti-1352	202	55	60	60	NUM
dti-1352	202	56	seconds	second	NOUN
dti-1352	202	57	)	)	PUNCT
dti-1352	202	58	of	of	ADP
dti-1352	202	59	the	the	DET
dti-1352	202	60	mwm	mwm	NOUN
dti-1352	202	61	test	test	NOUN
dti-1352	202	62	.	.	PUNCT
dti-1352	203	1	the	the	DET
dti-1352	203	2	data	datum	NOUN
dti-1352	203	3	are	be	AUX
dti-1352	203	4	expressed	express	VERB
dti-1352	203	5	as	as	ADP
dti-1352	203	6	the	the	DET
dti-1352	203	7	mean	mean	PROPN
dti-1352	203	8	±	±	NUM
dti-1352	203	9	sem	sem	NOUN
dti-1352	203	10	values	value	NOUN
dti-1352	203	11	.	.	PUNCT
dti-1352	204	1	*	*	PUNCT
dti-1352	204	2	p	p	NOUN
dti-1352	204	3	,	,	PUNCT
dti-1352	204	4	0.001	0.001	NUM
dti-1352	204	5	vs.	vs.	ADP
dti-1352	204	6	non	non	ADJ
dti-1352	204	7	-	-	ADJ
dti-1352	204	8	stressed	stressed	ADJ
dti-1352	204	9	control	control	NOUN
dti-1352	204	10	group	group	NOUN
dti-1352	204	11	.	.	PUNCT
dti-1352	205	1	#	#	SYM
dti-1352	205	2	p	p	NOUN
dti-1352	205	3	,	,	PUNCT
dti-1352	205	4	0.05	0.05	NUM
dti-1352	205	5	,	,	PUNCT
dti-1352	205	6	#	#	SYM
dti-1352	205	7	#	#	SYM
dti-1352	205	8	p	p	NOUN
dti-1352	205	9	,	,	PUNCT
dti-1352	205	10	0.01	0.01	NUM
dti-1352	205	11	,	,	PUNCT
dti-1352	205	12	#	#	SYM
dti-1352	205	13	#	#	SYM
dti-1352	205	14	#	#	SYM
dti-1352	205	15	p	p	NOUN
dti-1352	205	16	,	,	PUNCT
dti-1352	205	17	0.001	0.001	NUM
dti-1352	205	18	vs.	vs.	ADP
dti-1352	205	19	stressed	stress	VERB
dti-1352	205	20	control	control	PROPN
dti-1352	205	21	group	group	PROPN
dti-1352	205	22	.	.	PUNCT
dti-1352	206	1	significantly	significantly	ADV
dti-1352	206	2	shortened	shorten	VERB
dti-1352	206	3	the	the	DET
dti-1352	206	4	escape	escape	NOUN
dti-1352	206	5	latency	latency	NOUN
dti-1352	206	6	in	in	ADP
dti-1352	206	7	the	the	DET
dti-1352	206	8	familiarization	familiarization	NOUN
dti-1352	206	9	session	session	NOUN
dti-1352	206	10	(	(	PUNCT
dti-1352	206	11	p	p	NOUN
dti-1352	206	12	,	,	PUNCT
dti-1352	206	13	0.05	0.05	NUM
dti-1352	206	14	and	and	CCONJ
dti-1352	206	15	p	p	NOUN
dti-1352	206	16	,	,	PUNCT
dti-1352	206	17	0.01	0.01	NUM
dti-1352	206	18	;	;	PUNCT
dti-1352	206	19	respectively	respectively	ADV
dti-1352	206	20	)	)	PUNCT
dti-1352	206	21	and	and	CCONJ
dti-1352	206	22	in	in	ADP
dti-1352	206	23	the	the	DET
dti-1352	206	24	other	other	ADJ
dti-1352	206	25	sessions	session	NOUN
dti-1352	206	26	(	(	PUNCT
dti-1352	206	27	p	p	NOUN
dti-1352	206	28	,	,	PUNCT
dti-1352	206	29	0.001	0.001	NUM
dti-1352	206	30	)	)	PUNCT
dti-1352	206	31	in	in	ADP
dti-1352	206	32	stressed	stress	VERB
dti-1352	206	33	animals	animal	NOUN
dti-1352	206	34	(	(	PUNCT
dti-1352	206	35	fig	fig	NOUN
dti-1352	206	36	.	.	PUNCT
dti-1352	206	37	4a	4a	NUM
dti-1352	206	38	)	)	PUNCT
dti-1352	206	39	.	.	PUNCT
dti-1352	207	1	a	a	DET
dti-1352	207	2	significant	significant	ADJ
dti-1352	207	3	difference	difference	NOUN
dti-1352	207	4	was	be	AUX
dti-1352	207	5	observed	observe	VERB
dti-1352	207	6	among	among	ADP
dti-1352	207	7	all	all	DET
dti-1352	207	8	drug	drug	NOUN
dti-1352	207	9	groups	group	NOUN
dti-1352	207	10	in	in	ADP
dti-1352	207	11	the	the	DET
dti-1352	207	12	time	time	NOUN
dti-1352	207	13	spent	spend	VERB
dti-1352	207	14	in	in	ADP
dti-1352	207	15	the	the	DET
dti-1352	207	16	target	target	NOUN
dti-1352	207	17	quadrant	quadrant	NOUN
dti-1352	207	18	in	in	ADP
dti-1352	207	19	probe	probe	NOUN
dti-1352	207	20	trial	trial	NOUN
dti-1352	207	21	of	of	ADP
dti-1352	207	22	mwm	mwm	NOUN
dti-1352	207	23	test	test	NOUN
dti-1352	207	24	[	[	X
dti-1352	207	25	f(5,41	f(5,41	NOUN
dti-1352	207	26	)	)	PUNCT
dti-1352	207	27	=	=	SYM
dti-1352	207	28	6.27	6.27	NUM
dti-1352	207	29	;	;	PUNCT
dti-1352	207	30	p	p	PROPN
dti-1352	207	31	=	=	SYM
dti-1352	207	32	0.0003	0.0003	NUM
dti-1352	207	33	;	;	PUNCT
dti-1352	207	34	figure	figure	NOUN
dti-1352	207	35	4b	4b	PROPN
dti-1352	207	36	]	]	PUNCT
dti-1352	207	37	.	.	PUNCT
dti-1352	208	1	stressed	stress	VERB
dti-1352	208	2	control	control	NOUN
dti-1352	208	3	animals	animal	NOUN
dti-1352	208	4	significantly	significantly	ADV
dti-1352	208	5	decreased	decrease	VERB
dti-1352	208	6	the	the	DET
dti-1352	208	7	time	time	NOUN
dti-1352	208	8	spent	spend	VERB
dti-1352	208	9	in	in	ADP
dti-1352	208	10	the	the	DET
dti-1352	208	11	escape	escape	NOUN
dti-1352	208	12	platform	platform	NOUN
dti-1352	208	13	quadrant	quadrant	NOUN
dti-1352	208	14	(	(	PUNCT
dti-1352	208	15	p	p	X
dti-1352	208	16	,	,	PUNCT
dti-1352	208	17	0.001	0.001	NUM
dti-1352	208	18	)	)	PUNCT
dti-1352	208	19	compared	compare	VERB
dti-1352	208	20	to	to	ADP
dti-1352	208	21	non	non	ADJ
dti-1352	208	22	-	-	ADJ
dti-1352	208	23	stressed	stressed	ADJ
dti-1352	208	24	animals	animal	NOUN
dti-1352	208	25	,	,	PUNCT
dti-1352	208	26	and	and	CCONJ
dti-1352	208	27	both	both	DET
dti-1352	208	28	melatonin	melatonin	NOUN
dti-1352	208	29	(	(	PUNCT
dti-1352	208	30	p	p	NOUN
dti-1352	208	31	,	,	PUNCT
dti-1352	208	32	0.05	0.05	NUM
dti-1352	208	33	)	)	PUNCT
dti-1352	208	34	and	and	CCONJ
dti-1352	208	35	agomelatine	agomelatine	PROPN
dti-1352	208	36	reversed	reverse	VERB
dti-1352	208	37	this	this	DET
dti-1352	208	38	effect	effect	NOUN
dti-1352	208	39	;	;	PUNCT
dti-1352	208	40	agomelatine	agomelatine	PROPN
dti-1352	208	41	had	have	VERB
dti-1352	208	42	a	a	DET
dti-1352	208	43	higher	high	ADJ
dti-1352	208	44	impact	impact	NOUN
dti-1352	208	45	than	than	ADP
dti-1352	208	46	melatonin	melatonin	NOUN
dti-1352	208	47	(	(	PUNCT
dti-1352	208	48	p	p	NOUN
dti-1352	208	49	,	,	PUNCT
dti-1352	208	50	0.01	0.01	NUM
dti-1352	208	51	;	;	PUNCT
dti-1352	208	52	figure	figure	NOUN
dti-1352	208	53	4b	4b	PROPN
dti-1352	208	54	)	)	PUNCT
dti-1352	208	55	.	.	PUNCT
dti-1352	209	1	the	the	DET
dti-1352	209	2	mean	mean	ADJ
dti-1352	209	3	distance	distance	NOUN
dti-1352	209	4	traveled	travel	VERB
dti-1352	209	5	by	by	ADP
dti-1352	209	6	the	the	DET
dti-1352	209	7	mice	mouse	NOUN
dti-1352	209	8	to	to	ADP
dti-1352	209	9	the	the	DET
dti-1352	209	10	platform	platform	NOUN
dti-1352	209	11	in	in	ADP
dti-1352	209	12	the	the	DET
dti-1352	209	13	probe	probe	NOUN
dti-1352	209	14	trial	trial	NOUN
dti-1352	209	15	of	of	ADP
dti-1352	209	16	the	the	DET
dti-1352	209	17	mwm	mwm	NOUN
dti-1352	209	18	test	test	NOUN
dti-1352	209	19	was	be	AUX
dti-1352	209	20	significantly	significantly	ADV
dti-1352	209	21	different	different	ADJ
dti-1352	209	22	between	between	ADP
dti-1352	209	23	the	the	DET
dti-1352	209	24	drug	drug	NOUN
dti-1352	209	25	groups	group	NOUN
dti-1352	209	26	[	[	X
dti-1352	209	27	f(5,41	f(5,41	NOUN
dti-1352	209	28	)	)	PUNCT
dti-1352	209	29	=	=	NOUN
dti-1352	210	1	3.98	3.98	NUM
dti-1352	210	2	;	;	PUNCT
dti-1352	210	3	p	p	X
dti-1352	210	4	=	=	NOUN
dti-1352	210	5	0.005	0.005	NUM
dti-1352	210	6	;	;	PUNCT
dti-1352	210	7	http://www.la-press.com	http://www.la-press.com	X
dti-1352	210	8	gumuslu	gumuslu	PROPN
dti-1352	210	9	et	et	PROPN
dti-1352	210	10	al	al	PROPN
dti-1352	210	11	18	18	NUM
dti-1352	210	12	drug	drug	NOUN
dti-1352	210	13	target	target	NOUN
dti-1352	210	14	insights	insight	VERB
dti-1352	210	15	2014:8	2014:8	NUM
dti-1352	210	16	figure	figure	NOUN
dti-1352	210	17	4c	4c	NOUN
dti-1352	210	18	]	]	PUNCT
dti-1352	210	19	.	.	PUNCT
dti-1352	211	1	stress	stress	NOUN
dti-1352	211	2	significantly	significantly	ADV
dti-1352	211	3	increased	increase	VERB
dti-1352	211	4	the	the	DET
dti-1352	211	5	mean	mean	ADJ
dti-1352	211	6	distance	distance	NOUN
dti-1352	211	7	traveled	travel	VERB
dti-1352	211	8	to	to	ADP
dti-1352	211	9	the	the	DET
dti-1352	211	10	platform	platform	NOUN
dti-1352	211	11	(	(	PUNCT
dti-1352	211	12	p	p	X
dti-1352	211	13	,	,	PUNCT
dti-1352	211	14	0.01	0.01	NUM
dti-1352	211	15	)	)	PUNCT
dti-1352	211	16	compared	compare	VERB
dti-1352	211	17	to	to	ADP
dti-1352	211	18	the	the	DET
dti-1352	211	19	nonstressed	nonstressed	ADJ
dti-1352	211	20	control	control	NOUN
dti-1352	211	21	group	group	NOUN
dti-1352	211	22	.	.	PUNCT
dti-1352	212	1	melatonin	melatonin	NOUN
dti-1352	212	2	(	(	PUNCT
dti-1352	212	3	p	p	NOUN
dti-1352	212	4	,	,	PUNCT
dti-1352	212	5	0.05	0.05	NUM
dti-1352	212	6	)	)	PUNCT
dti-1352	212	7	and	and	CCONJ
dti-1352	212	8	agomelatine	agomelatine	PROPN
dti-1352	212	9	significantly	significantly	ADV
dti-1352	212	10	reversed	reverse	VERB
dti-1352	212	11	this	this	DET
dti-1352	212	12	effect	effect	NOUN
dti-1352	212	13	;	;	PUNCT
dti-1352	212	14	agomelatine	agomelatine	PROPN
dti-1352	212	15	had	have	VERB
dti-1352	212	16	a	a	DET
dti-1352	212	17	higher	high	ADJ
dti-1352	212	18	impact	impact	NOUN
dti-1352	212	19	(	(	PUNCT
dti-1352	212	20	p	p	X
dti-1352	212	21	,	,	PUNCT
dti-1352	212	22	0.01	0.01	NUM
dti-1352	212	23	;	;	PUNCT
dti-1352	212	24	figure	figure	NOUN
dti-1352	212	25	4c	4c	NOUN
dti-1352	212	26	)	)	PUNCT
dti-1352	212	27	.	.	PUNCT
dti-1352	213	1	each	each	DET
dti-1352	213	2	treatment	treatment	NOUN
dti-1352	213	3	group	group	NOUN
dti-1352	213	4	did	do	AUX
dti-1352	213	5	not	not	PART
dti-1352	213	6	significantly	significantly	ADV
dti-1352	213	7	differ	differ	VERB
dti-1352	213	8	in	in	ADP
dti-1352	213	9	swimming	swimming	NOUN
dti-1352	213	10	speed	speed	NOUN
dti-1352	213	11	[	[	X
dti-1352	213	12	f(5,41	f(5,41	NOUN
dti-1352	213	13	)	)	PUNCT
dti-1352	213	14	=	=	NUM
dti-1352	213	15	1.32	1.32	NUM
dti-1352	213	16	;	;	PUNCT
dti-1352	213	17	p	p	X
dti-1352	213	18	=	=	NOUN
dti-1352	213	19	0.27	0.27	NUM
dti-1352	213	20	;	;	PUNCT
dti-1352	213	21	figure	figure	NOUN
dti-1352	213	22	4d	4d	NUM
dti-1352	213	23	]	]	PUNCT
dti-1352	213	24	in	in	ADP
dti-1352	213	25	the	the	DET
dti-1352	213	26	probe	probe	NOUN
dti-1352	213	27	trial	trial	NOUN
dti-1352	213	28	of	of	ADP
dti-1352	213	29	the	the	DET
dti-1352	213	30	mwm	mwm	NOUN
dti-1352	213	31	test	test	NOUN
dti-1352	213	32	.	.	PUNCT
dti-1352	214	1	effects	effect	NOUN
dti-1352	214	2	of	of	ADP
dti-1352	214	3	drugs	drug	NOUN
dti-1352	214	4	on	on	ADP
dti-1352	214	5	creb	creb	NOUN
dti-1352	214	6	and	and	CCONJ
dti-1352	214	7	bdnf	bdnf	ADJ
dti-1352	214	8	gene	gene	NOUN
dti-1352	214	9	expression	expression	NOUN
dti-1352	214	10	.	.	PUNCT
dti-1352	215	1	in	in	ADP
dti-1352	215	2	evaluating	evaluate	VERB
dti-1352	215	3	plasticity	plasticity	NOUN
dti-1352	215	4	-	-	PUNCT
dti-1352	215	5	related	relate	VERB
dti-1352	215	6	genes	gene	NOUN
dti-1352	215	7	,	,	PUNCT
dti-1352	215	8	we	we	PRON
dti-1352	215	9	measured	measure	VERB
dti-1352	215	10	mrna	mrna	PROPN
dti-1352	215	11	levels	level	NOUN
dti-1352	215	12	in	in	ADP
dti-1352	215	13	the	the	DET
dti-1352	215	14	hippocampus	hippocampus	NOUN
dti-1352	215	15	of	of	ADP
dti-1352	215	16	mice	mouse	NOUN
dti-1352	215	17	subjected	subject	VERB
dti-1352	215	18	to	to	ADP
dti-1352	215	19	ucms	ucms	NOUN
dti-1352	215	20	/	/	SYM
dti-1352	215	21	drug	drug	NOUN
dti-1352	215	22	treatment	treatment	NOUN
dti-1352	215	23	using	use	VERB
dti-1352	215	24	quantitative	quantitative	ADJ
dti-1352	215	25	rt	rt	NOUN
dti-1352	215	26	-	-	PUNCT
dti-1352	215	27	pcr	pcr	NOUN
dti-1352	215	28	.	.	PUNCT
dti-1352	216	1	decreased	decrease	VERB
dti-1352	216	2	bdnf	bdnf	ADJ
dti-1352	216	3	and	and	CCONJ
dti-1352	216	4	creb	creb	NOUN
dti-1352	216	5	expression	expression	NOUN
dti-1352	216	6	might	might	AUX
dti-1352	216	7	indicate	indicate	VERB
dti-1352	216	8	both	both	PRON
dti-1352	216	9	stress	stress	NOUN
dti-1352	216	10	and	and	CCONJ
dti-1352	216	11	cognitive	cognitive	ADJ
dti-1352	216	12	impairment	impairment	NOUN
dti-1352	216	13	.	.	PUNCT
dti-1352	217	1	to	to	PART
dti-1352	217	2	determine	determine	VERB
dti-1352	217	3	whether	whether	SCONJ
dti-1352	217	4	downregulation	downregulation	NOUN
dti-1352	217	5	of	of	ADP
dti-1352	217	6	gene	gene	NOUN
dti-1352	217	7	expression	expression	NOUN
dti-1352	217	8	can	can	AUX
dti-1352	217	9	be	be	AUX
dti-1352	217	10	prevented	prevent	VERB
dti-1352	217	11	by	by	ADP
dti-1352	217	12	antidepressant	antidepressant	ADJ
dti-1352	217	13	treatment	treatment	NOUN
dti-1352	217	14	,	,	PUNCT
dti-1352	217	15	melatonin	melatonin	NOUN
dti-1352	217	16	or	or	CCONJ
dti-1352	217	17	agomelatine	agomelatine	NOUN
dti-1352	217	18	was	be	AUX
dti-1352	217	19	administered	administer	VERB
dti-1352	217	20	for	for	ADP
dti-1352	217	21	35	35	NUM
dti-1352	217	22	days	day	NOUN
dti-1352	217	23	to	to	ADP
dti-1352	217	24	mice	mouse	NOUN
dti-1352	217	25	subjected	subject	VERB
dti-1352	217	26	to	to	ADP
dti-1352	217	27	ucms	ucm	NOUN
dti-1352	217	28	.	.	PUNCT
dti-1352	218	1	our	our	PRON
dti-1352	218	2	results	result	NOUN
dti-1352	218	3	demonstrated	demonstrate	VERB
dti-1352	218	4	that	that	SCONJ
dti-1352	218	5	mrna	mrna	PROPN
dti-1352	218	6	levels	level	NOUN
dti-1352	218	7	of	of	ADP
dti-1352	218	8	the	the	DET
dti-1352	218	9	neurotrophin	neurotrophin	PROPN
dti-1352	218	10	family	family	PROPN
dti-1352	218	11	member	member	NOUN
dti-1352	218	12	bdnf	bdnf	PROPN
dti-1352	218	13	,	,	PUNCT
dti-1352	218	14	which	which	PRON
dti-1352	218	15	has	have	AUX
dti-1352	218	16	been	be	AUX
dti-1352	218	17	studied	study	VERB
dti-1352	218	18	in	in	ADP
dti-1352	218	19	relation	relation	NOUN
dti-1352	218	20	to	to	ADP
dti-1352	218	21	the	the	DET
dti-1352	218	22	stress	stress	NOUN
dti-1352	218	23	response	response	NOUN
dti-1352	218	24	,	,	PUNCT
dti-1352	218	25	were	be	AUX
dti-1352	218	26	reduced	reduce	VERB
dti-1352	218	27	in	in	ADP
dti-1352	218	28	the	the	DET
dti-1352	218	29	hippocampus	hippocampus	NOUN
dti-1352	218	30	of	of	ADP
dti-1352	218	31	the	the	DET
dti-1352	218	32	mice	mouse	NOUN
dti-1352	218	33	subjected	subject	VERB
dti-1352	218	34	to	to	ADP
dti-1352	218	35	ucms	ucm	NOUN
dti-1352	218	36	.	.	PUNCT
dti-1352	219	1	we	we	PRON
dti-1352	219	2	also	also	ADV
dti-1352	219	3	measured	measure	VERB
dti-1352	219	4	hippocampal	hippocampal	ADJ
dti-1352	219	5	mrna	mrna	NOUN
dti-1352	219	6	expression	expression	NOUN
dti-1352	219	7	levels	level	NOUN
dti-1352	219	8	for	for	ADP
dti-1352	219	9	creb	creb	NOUN
dti-1352	219	10	,	,	PUNCT
dti-1352	219	11	a	a	DET
dti-1352	219	12	transcription	transcription	NOUN
dti-1352	219	13	factor	factor	NOUN
dti-1352	219	14	that	that	PRON
dti-1352	219	15	regulates	regulate	VERB
dti-1352	219	16	bdnf	bdnf	ADJ
dti-1352	219	17	in	in	ADP
dti-1352	219	18	response	response	NOUN
dti-1352	219	19	to	to	ADP
dti-1352	219	20	drug	drug	NOUN
dti-1352	219	21	treatment	treatment	NOUN
dti-1352	219	22	.	.	PUNCT
dti-1352	220	1	ucms	ucm	NOUN
dti-1352	220	2	caused	cause	VERB
dti-1352	220	3	a	a	DET
dti-1352	220	4	reduction	reduction	NOUN
dti-1352	220	5	in	in	ADP
dti-1352	220	6	creb	creb	PROPN
dti-1352	220	7	mrna	mrna	PROPN
dti-1352	220	8	levels	level	NOUN
dti-1352	220	9	in	in	ADP
dti-1352	220	10	stressed	stress	VERB
dti-1352	220	11	animals	animal	NOUN
dti-1352	220	12	.	.	PUNCT
dti-1352	221	1	melatonin	melatonin	NOUN
dti-1352	221	2	or	or	CCONJ
dti-1352	221	3	agomelatine	agomelatine	PROPN
dti-1352	221	4	treatment	treatment	NOUN
dti-1352	221	5	significantly	significantly	ADV
dti-1352	221	6	reversed	reverse	VERB
dti-1352	221	7	ucms	ucms	NOUN
dti-1352	221	8	-	-	PUNCT
dti-1352	221	9	induced	induce	VERB
dti-1352	221	10	downregulation	downregulation	NOUN
dti-1352	221	11	of	of	ADP
dti-1352	221	12	creb	creb	NOUN
dti-1352	221	13	and	and	CCONJ
dti-1352	221	14	bdnf	bdnf	ADJ
dti-1352	221	15	gene	gene	NOUN
dti-1352	221	16	expression	expression	NOUN
dti-1352	221	17	.	.	PUNCT
dti-1352	222	1	our	our	PRON
dti-1352	222	2	results	result	NOUN
dti-1352	222	3	are	be	AUX
dti-1352	222	4	in	in	ADP
dti-1352	222	5	agreement	agreement	NOUN
dti-1352	222	6	with	with	ADP
dti-1352	222	7	data	datum	NOUN
dti-1352	222	8	from	from	ADP
dti-1352	222	9	similar	similar	ADJ
dti-1352	222	10	studies.34,35	studies.34,35	NOUN
dti-1352	222	11	the	the	DET
dti-1352	222	12	gene	gene	NOUN
dti-1352	222	13	expression	expression	NOUN
dti-1352	222	14	observed	observe	VERB
dti-1352	222	15	in	in	ADP
dti-1352	222	16	each	each	DET
dti-1352	222	17	group	group	NOUN
dti-1352	222	18	is	be	AUX
dti-1352	222	19	shown	show	VERB
dti-1352	222	20	in	in	ADP
dti-1352	222	21	table	table	NOUN
dti-1352	223	1	2	2	NUM
dti-1352	223	2	.	.	PUNCT
dti-1352	223	3	discussion	discussion	NOUN
dti-1352	223	4	stress	stress	NOUN
dti-1352	223	5	is	be	AUX
dti-1352	223	6	a	a	DET
dti-1352	223	7	known	know	VERB
dti-1352	223	8	risk	risk	NOUN
dti-1352	223	9	factor	factor	NOUN
dti-1352	223	10	in	in	ADP
dti-1352	223	11	the	the	DET
dti-1352	223	12	development	development	NOUN
dti-1352	223	13	of	of	ADP
dti-1352	223	14	many	many	ADJ
dti-1352	223	15	neuropsychiatric	neuropsychiatric	ADJ
dti-1352	223	16	disorders	disorder	NOUN
dti-1352	223	17	,	,	PUNCT
dti-1352	223	18	including	include	VERB
dti-1352	223	19	depression.2	depression.2	PRON
dti-1352	223	20	moreover	moreover	ADV
dti-1352	223	21	,	,	PUNCT
dti-1352	223	22	because	because	SCONJ
dti-1352	223	23	stress	stress	NOUN
dti-1352	223	24	-	-	PUNCT
dti-1352	223	25	induced	induce	VERB
dti-1352	223	26	memory	memory	NOUN
dti-1352	223	27	impairment	impairment	NOUN
dti-1352	223	28	is	be	AUX
dti-1352	223	29	commonly	commonly	ADV
dti-1352	223	30	reported	report	VERB
dti-1352	223	31	in	in	ADP
dti-1352	223	32	stress	stress	NOUN
dti-1352	223	33	-	-	PUNCT
dti-1352	223	34	related	relate	VERB
dti-1352	223	35	psychopathologies,3	psychopathologies,3	NOUN
dti-1352	223	36	there	there	PRON
dti-1352	223	37	is	be	VERB
dti-1352	223	38	therapeutic	therapeutic	ADJ
dti-1352	223	39	relevance	relevance	NOUN
dti-1352	223	40	of	of	ADP
dti-1352	223	41	the	the	DET
dti-1352	223	42	use	use	NOUN
dti-1352	223	43	of	of	ADP
dti-1352	223	44	antidepressant	antidepressant	ADJ
dti-1352	223	45	treatments	treatment	NOUN
dti-1352	223	46	to	to	PART
dti-1352	223	47	prevent	prevent	VERB
dti-1352	223	48	stress	stress	NOUN
dti-1352	223	49	-	-	PUNCT
dti-1352	223	50	induced	induce	VERB
dti-1352	223	51	cognitive	cognitive	ADJ
dti-1352	223	52	deficits.1	deficits.1	NOUN
dti-1352	223	53	both	both	CCONJ
dti-1352	223	54	chronic	chronic	ADJ
dti-1352	223	55	mild	mild	ADJ
dti-1352	223	56	stress	stress	NOUN
dti-1352	223	57	and	and	CCONJ
dti-1352	223	58	learned	learn	VERB
dti-1352	223	59	helplessness	helplessness	NOUN
dti-1352	223	60	significantly	significantly	ADV
dti-1352	223	61	diminish	diminish	VERB
dti-1352	223	62	the	the	DET
dti-1352	223	63	cognitive	cognitive	ADJ
dti-1352	223	64	performance	performance	NOUN
dti-1352	223	65	of	of	ADP
dti-1352	223	66	mice	mouse	NOUN
dti-1352	223	67	in	in	ADP
dti-1352	223	68	the	the	DET
dti-1352	223	69	mwm	mwm	NOUN
dti-1352	223	70	test	test	NOUN
dti-1352	223	71	,	,	PUNCT
dti-1352	223	72	and	and	CCONJ
dti-1352	223	73	animals	animal	NOUN
dti-1352	223	74	treated	treat	VERB
dti-1352	223	75	with	with	ADP
dti-1352	223	76	antidepressants	antidepressant	NOUN
dti-1352	223	77	exhibit	exhibit	VERB
dti-1352	223	78	significantly	significantly	ADV
dti-1352	223	79	enhanced	enhance	VERB
dti-1352	223	80	cognitive	cognitive	ADJ
dti-1352	223	81	performance.35	performance.35	NOUN
dti-1352	223	82	the	the	DET
dti-1352	223	83	chronic	chronic	ADJ
dti-1352	223	84	administration	administration	NOUN
dti-1352	223	85	of	of	ADP
dti-1352	223	86	agomelatine	agomelatine	PROPN
dti-1352	223	87	produced	produce	VERB
dti-1352	223	88	antidepressant	antidepressant	ADJ
dti-1352	223	89	-	-	PUNCT
dti-1352	223	90	like	like	ADJ
dti-1352	223	91	effects	effect	NOUN
dti-1352	223	92	in	in	ADP
dti-1352	223	93	the	the	DET
dti-1352	223	94	chronic	chronic	ADJ
dti-1352	223	95	mild	mild	ADJ
dti-1352	223	96	stress	stress	NOUN
dti-1352	223	97	model	model	NOUN
dti-1352	223	98	of	of	ADP
dti-1352	223	99	depression36	depression36	NOUN
dti-1352	223	100	and	and	CCONJ
dti-1352	223	101	improved	improve	VERB
dti-1352	223	102	learned	learn	VERB
dti-1352	223	103	helplessness	helplessness	NOUN
dti-1352	223	104	in	in	ADP
dti-1352	223	105	a	a	DET
dti-1352	223	106	model	model	NOUN
dti-1352	223	107	of	of	ADP
dti-1352	223	108	depression	depression	NOUN
dti-1352	223	109	-	-	PUNCT
dti-1352	223	110	induced	induce	VERB
dti-1352	223	111	avoidance	avoidance	NOUN
dti-1352	223	112	learning	learn	VERB
dti-1352	223	113	deficits	deficit	NOUN
dti-1352	223	114	.	.	PUNCT
dti-1352	224	1	in	in	ADP
dti-1352	224	2	our	our	PRON
dti-1352	224	3	study	study	NOUN
dti-1352	224	4	,	,	PUNCT
dti-1352	224	5	stress	stress	NOUN
dti-1352	224	6	-	-	PUNCT
dti-1352	224	7	induced	induce	VERB
dti-1352	224	8	a	a	DET
dti-1352	224	9	significant	significant	ADJ
dti-1352	224	10	deterioration	deterioration	NOUN
dti-1352	224	11	of	of	ADP
dti-1352	224	12	memory	memory	NOUN
dti-1352	224	13	in	in	ADP
dti-1352	224	14	the	the	DET
dti-1352	224	15	pa	pa	PROPN
dti-1352	224	16	,	,	PUNCT
dti-1352	224	17	mepm	mepm	PROPN
dti-1352	224	18	,	,	PUNCT
dti-1352	224	19	nor	nor	CCONJ
dti-1352	224	20	,	,	PUNCT
dti-1352	224	21	and	and	CCONJ
dti-1352	224	22	mwm	mwm	NOUN
dti-1352	224	23	tests	test	NOUN
dti-1352	224	24	,	,	PUNCT
dti-1352	224	25	and	and	CCONJ
dti-1352	224	26	agomelatine	agomelatine	PROPN
dti-1352	224	27	ameliorated	ameliorate	VERB
dti-1352	224	28	these	these	DET
dti-1352	224	29	effects	effect	NOUN
dti-1352	224	30	in	in	ADP
dti-1352	224	31	nor	nor	CCONJ
dti-1352	224	32	and	and	CCONJ
dti-1352	224	33	mwm	mwm	NOUN
dti-1352	224	34	tests	test	NOUN
dti-1352	224	35	while	while	SCONJ
dti-1352	224	36	it	it	PRON
dti-1352	224	37	had	have	VERB
dti-1352	224	38	a	a	DET
dti-1352	224	39	partial	partial	ADJ
dti-1352	224	40	effect	effect	NOUN
dti-1352	224	41	in	in	ADP
dti-1352	224	42	the	the	DET
dti-1352	224	43	pa	pa	PROPN
dti-1352	224	44	and	and	CCONJ
dti-1352	224	45	mepm	mepm	NOUN
dti-1352	224	46	tests	test	NOUN
dti-1352	224	47	.	.	PUNCT
dti-1352	225	1	agomelatine	agomelatine	PROPN
dti-1352	225	2	,	,	PUNCT
dti-1352	225	3	a	a	DET
dti-1352	225	4	novel	novel	ADJ
dti-1352	225	5	antidepressant	antidepressant	NOUN
dti-1352	225	6	with	with	ADP
dti-1352	225	7	established	establish	VERB
dti-1352	225	8	clinical	clinical	ADJ
dti-1352	225	9	efficacy,6	efficacy,6	NOUN
dti-1352	225	10	is	be	AUX
dti-1352	225	11	an	an	DET
dti-1352	225	12	agonist	agonist	NOUN
dti-1352	225	13	of	of	ADP
dti-1352	225	14	the	the	DET
dti-1352	225	15	melatonin	melatonin	NOUN
dti-1352	225	16	mt1	mt1	PROPN
dti-1352	225	17	and	and	CCONJ
dti-1352	225	18	mt2	mt2	PROPN
dti-1352	225	19	receptors37	receptors37	PROPN
dti-1352	225	20	and	and	CCONJ
dti-1352	225	21	has	have	AUX
dti-1352	225	22	a	a	DET
dti-1352	225	23	potent	potent	ADJ
dti-1352	225	24	antagonistic	antagonistic	ADJ
dti-1352	225	25	activity	activity	NOUN
dti-1352	225	26	on	on	ADP
dti-1352	225	27	serotonergic	serotonergic	ADJ
dti-1352	225	28	5	5	NUM
dti-1352	225	29	-	-	NOUN
dti-1352	225	30	ht2c	ht2c	NOUN
dti-1352	225	31	receptors.7	receptors.7	VERB
dti-1352	225	32	the	the	DET
dti-1352	225	33	affinity	affinity	NOUN
dti-1352	225	34	of	of	ADP
dti-1352	225	35	agomelatine	agomelatine	NOUN
dti-1352	225	36	for	for	ADP
dti-1352	225	37	melatonin	melatonin	NOUN
dti-1352	225	38	receptors	receptor	NOUN
dti-1352	225	39	is	be	AUX
dti-1352	225	40	comparable	comparable	ADJ
dti-1352	225	41	with	with	ADP
dti-1352	225	42	that	that	PRON
dti-1352	225	43	of	of	ADP
dti-1352	225	44	melatonin.38	melatonin.38	PROPN
dti-1352	225	45	melatonin	melatonin	NOUN
dti-1352	225	46	produced	produce	VERB
dti-1352	225	47	in	in	ADP
dti-1352	225	48	the	the	DET
dti-1352	225	49	pineal	pineal	NOUN
dti-1352	225	50	gland	gland	NOUN
dti-1352	225	51	during	during	ADP
dti-1352	225	52	periods	period	NOUN
dti-1352	225	53	of	of	ADP
dti-1352	225	54	darkness	darkness	NOUN
dti-1352	225	55	plays	play	VERB
dti-1352	225	56	a	a	DET
dti-1352	225	57	key	key	ADJ
dti-1352	225	58	role	role	NOUN
dti-1352	225	59	in	in	ADP
dti-1352	225	60	the	the	DET
dti-1352	225	61	regulation	regulation	NOUN
dti-1352	225	62	of	of	ADP
dti-1352	225	63	circadian	circadian	ADJ
dti-1352	225	64	rhythms.8	rhythms.8	PROPN
dti-1352	225	65	it	it	PRON
dti-1352	225	66	has	have	VERB
dti-1352	225	67	a	a	DET
dti-1352	225	68	short	short	ADJ
dti-1352	225	69	half	half	ADJ
dti-1352	225	70	-	-	PUNCT
dti-1352	225	71	life	life	NOUN
dti-1352	225	72	and	and	CCONJ
dti-1352	225	73	is	be	AUX
dti-1352	225	74	extensively	extensively	ADV
dti-1352	225	75	metabolized	metabolize	VERB
dti-1352	225	76	,	,	PUNCT
dti-1352	225	77	leading	lead	VERB
dti-1352	225	78	to	to	ADP
dti-1352	225	79	poor	poor	ADJ
dti-1352	225	80	bioavailability	bioavailability	NOUN
dti-1352	225	81	.	.	PUNCT
dti-1352	226	1	moreover	moreover	ADV
dti-1352	226	2	,	,	PUNCT
dti-1352	226	3	the	the	DET
dti-1352	226	4	antidepressant	antidepressant	ADJ
dti-1352	226	5	-	-	PUNCT
dti-1352	226	6	like	like	ADJ
dti-1352	226	7	activity	activity	NOUN
dti-1352	226	8	of	of	ADP
dti-1352	226	9	agomelatine	agomelatine	NOUN
dti-1352	226	10	in	in	ADP
dti-1352	226	11	the	the	DET
dti-1352	226	12	rat	rat	NOUN
dti-1352	226	13	cms	cms	PROPN
dti-1352	226	14	model	model	NOUN
dti-1352	226	15	of	of	ADP
dti-1352	226	16	depression	depression	NOUN
dti-1352	226	17	is	be	AUX
dti-1352	226	18	independent	independent	ADJ
dti-1352	226	19	of	of	ADP
dti-1352	226	20	the	the	DET
dti-1352	226	21	time	time	NOUN
dti-1352	226	22	of	of	ADP
dti-1352	226	23	drug	drug	NOUN
dti-1352	226	24	administration	administration	NOUN
dti-1352	226	25	,	,	PUNCT
dti-1352	226	26	while	while	SCONJ
dti-1352	226	27	melatonin	melatonin	NOUN
dti-1352	226	28	has	have	VERB
dti-1352	226	29	no	no	DET
dti-1352	226	30	antidepressant	antidepressant	ADJ
dti-1352	226	31	-	-	PUNCT
dti-1352	226	32	like	like	ADJ
dti-1352	226	33	activity	activity	NOUN
dti-1352	226	34	after	after	ADP
dti-1352	226	35	administration	administration	NOUN
dti-1352	226	36	in	in	ADP
dti-1352	226	37	the	the	DET
dti-1352	226	38	morning.9	morning.9	PROPN
dti-1352	226	39	the	the	DET
dti-1352	226	40	search	search	NOUN
dti-1352	226	41	for	for	ADP
dti-1352	226	42	metabolically	metabolically	ADV
dti-1352	226	43	stable	stable	ADJ
dti-1352	226	44	analogs	analog	NOUN
dti-1352	226	45	with	with	ADP
dti-1352	226	46	new	new	ADJ
dti-1352	226	47	and	and	CCONJ
dti-1352	226	48	innovative	innovative	ADJ
dti-1352	226	49	properties	property	NOUN
dti-1352	226	50	resulted	result	VERB
dti-1352	226	51	in	in	ADP
dti-1352	226	52	the	the	DET
dti-1352	226	53	discovery	discovery	NOUN
dti-1352	226	54	of	of	ADP
dti-1352	226	55	agomelatine.39	agomelatine.39	PROPN
dti-1352	226	56	agomelatine	agomelatine	NOUN
dti-1352	226	57	-	-	PUNCT
dti-1352	226	58	induced	induce	VERB
dti-1352	226	59	molecular	molecular	ADJ
dti-1352	226	60	changes	change	NOUN
dti-1352	226	61	may	may	AUX
dti-1352	226	62	play	play	VERB
dti-1352	226	63	a	a	DET
dti-1352	226	64	role	role	NOUN
dti-1352	226	65	in	in	ADP
dti-1352	226	66	its	its	PRON
dti-1352	226	67	antidepressant	antidepressant	ADJ
dti-1352	226	68	and	and	CCONJ
dti-1352	226	69	pro	pro	ADJ
dti-1352	226	70	-	-	ADJ
dti-1352	226	71	cognitive	cognitive	ADJ
dti-1352	226	72	effects	effect	NOUN
dti-1352	226	73	and	and	CCONJ
dti-1352	226	74	may	may	AUX
dti-1352	226	75	be	be	AUX
dti-1352	226	76	attributed	attribute	VERB
dti-1352	226	77	to	to	ADP
dti-1352	226	78	synergy	synergy	NOUN
dti-1352	226	79	between	between	ADP
dti-1352	226	80	the	the	DET
dti-1352	226	81	5	5	NUM
dti-1352	226	82	-	-	PUNCT
dti-1352	226	83	ht2c	ht2c	NOUN
dti-1352	226	84	antagonist	antagonist	NOUN
dti-1352	226	85	and	and	CCONJ
dti-1352	226	86	melatonergic	melatonergic	NOUN
dti-1352	226	87	agonist	agonist	NOUN
dti-1352	226	88	properties	property	NOUN
dti-1352	226	89	of	of	ADP
dti-1352	226	90	the	the	DET
dti-1352	226	91	drug.6	drug.6	PROPN
dti-1352	226	92	agomelatine	agomelatine	PROPN
dti-1352	226	93	increased	increase	VERB
dti-1352	226	94	the	the	DET
dti-1352	226	95	release	release	NOUN
dti-1352	226	96	of	of	ADP
dti-1352	226	97	noradrenaline	noradrenaline	NOUN
dti-1352	226	98	and	and	CCONJ
dti-1352	226	99	dopamine	dopamine	NOUN
dti-1352	226	100	in	in	ADP
dti-1352	226	101	accordance	accordance	NOUN
dti-1352	226	102	with	with	ADP
dti-1352	226	103	its	its	PRON
dti-1352	226	104	5	5	NUM
dti-1352	226	105	-	-	PUNCT
dti-1352	226	106	ht2c	ht2c	NOUN
dti-1352	226	107	antagonist	antagonist	NOUN
dti-1352	226	108	properties.7	properties.7	NOUN
dti-1352	226	109	these	these	PRON
dti-1352	226	110	may	may	AUX
dti-1352	226	111	in	in	ADP
dti-1352	226	112	turn	turn	NOUN
dti-1352	226	113	be	be	AUX
dti-1352	226	114	associated	associate	VERB
dti-1352	226	115	with	with	ADP
dti-1352	226	116	the	the	DET
dti-1352	226	117	functional	functional	ADJ
dti-1352	226	118	output	output	NOUN
dti-1352	226	119	of	of	ADP
dti-1352	226	120	β	β	NOUN
dti-1352	226	121	-	-	ADJ
dti-1352	226	122	adrenergic	adrenergic	ADJ
dti-1352	226	123	d1	d1	NOUN
dti-1352	226	124	and	and	CCONJ
dti-1352	226	125	d2	d2	NOUN
dti-1352	226	126	receptors	receptor	NOUN
dti-1352	226	127	and	and	CCONJ
dti-1352	226	128	activation	activation	NOUN
dti-1352	226	129	or	or	CCONJ
dti-1352	226	130	inhibition	inhibition	NOUN
dti-1352	226	131	of	of	ADP
dti-1352	226	132	the	the	DET
dti-1352	226	133	camppka	camppka	NOUN
dti-1352	226	134	pathway	pathway	NOUN
dti-1352	226	135	,	,	PUNCT
dti-1352	226	136	which	which	PRON
dti-1352	226	137	is	be	AUX
dti-1352	226	138	postulated	postulate	VERB
dti-1352	226	139	to	to	PART
dti-1352	226	140	modulate	modulate	VERB
dti-1352	226	141	microtubule	microtubule	NOUN
dti-1352	226	142	dynamics40	dynamics40	NOUN
dti-1352	226	143	and	and	CCONJ
dti-1352	226	144	synaptic	synaptic	ADJ
dti-1352	226	145	plasticity.41	plasticity.41	NOUN
dti-1352	226	146	numerous	numerous	ADJ
dti-1352	226	147	findings	finding	NOUN
dti-1352	226	148	indicate	indicate	VERB
dti-1352	226	149	that	that	SCONJ
dti-1352	226	150	reduced	reduce	VERB
dti-1352	226	151	function	function	NOUN
dti-1352	226	152	of	of	ADP
dti-1352	226	153	5	5	NUM
dti-1352	226	154	-	-	PUNCT
dti-1352	226	155	ht2c	ht2c	NOUN
dti-1352	226	156	receptors	receptor	NOUN
dti-1352	226	157	may	may	AUX
dti-1352	226	158	be	be	AUX
dti-1352	226	159	involved	involve	VERB
dti-1352	226	160	in	in	ADP
dti-1352	226	161	the	the	DET
dti-1352	226	162	mechanism	mechanism	NOUN
dti-1352	226	163	by	by	ADP
dti-1352	226	164	which	which	PRON
dti-1352	226	165	antidepressants	antidepressant	NOUN
dti-1352	226	166	alleviate	alleviate	VERB
dti-1352	226	167	depression.42	depression.42	NOUN
dti-1352	226	168	the	the	DET
dti-1352	226	169	5	5	NUM
dti-1352	226	170	-	-	PUNCT
dti-1352	226	171	ht2c	ht2c	NOUN
dti-1352	226	172	receptor	receptor	NOUN
dti-1352	226	173	is	be	AUX
dti-1352	226	174	involved	involve	VERB
dti-1352	226	175	in	in	ADP
dti-1352	226	176	circadian	circadian	ADJ
dti-1352	226	177	rhythm	rhythm	NOUN
dti-1352	226	178	resynchronization,43	resynchronization,43	VERB
dti-1352	226	179	and	and	CCONJ
dti-1352	226	180	5	5	NUM
dti-1352	226	181	-	-	PUNCT
dti-1352	226	182	ht2c	ht2c	NOUN
dti-1352	226	183	receptor	receptor	NOUN
dti-1352	226	184	antagonists	antagonist	NOUN
dti-1352	226	185	prevent	prevent	VERB
dti-1352	226	186	the	the	DET
dti-1352	226	187	inhibitory	inhibitory	ADJ
dti-1352	226	188	effects	effect	NOUN
dti-1352	226	189	of	of	ADP
dti-1352	226	190	light	light	NOUN
dti-1352	226	191	on	on	ADP
dti-1352	226	192	melatonin	melatonin	NOUN
dti-1352	226	193	synthesis	synthesis	NOUN
dti-1352	226	194	.	.	PUNCT
dti-1352	227	1	in	in	ADP
dti-1352	227	2	mammals	mammal	NOUN
dti-1352	227	3	,	,	PUNCT
dti-1352	227	4	specific	specific	ADJ
dti-1352	227	5	m1	m1	NOUN
dti-1352	227	6	and	and	CCONJ
dti-1352	227	7	m2	m2	PROPN
dti-1352	227	8	receptors	receptor	NOUN
dti-1352	227	9	are	be	AUX
dti-1352	227	10	located	locate	VERB
dti-1352	227	11	mainly	mainly	ADV
dti-1352	227	12	in	in	ADP
dti-1352	227	13	suprachiasmatic	suprachiasmatic	ADJ
dti-1352	227	14	nuclei	nucleus	NOUN
dti-1352	227	15	in	in	ADP
dti-1352	227	16	the	the	DET
dti-1352	227	17	central	central	ADJ
dti-1352	227	18	nervous	nervous	ADJ
dti-1352	227	19	system	system	NOUN
dti-1352	227	20	and	and	CCONJ
dti-1352	227	21	in	in	ADP
dti-1352	227	22	some	some	DET
dti-1352	227	23	peripheral	peripheral	ADJ
dti-1352	227	24	sites	site	NOUN
dti-1352	227	25	.	.	PUNCT
dti-1352	228	1	moreover	moreover	ADV
dti-1352	228	2	,	,	PUNCT
dti-1352	228	3	the	the	DET
dti-1352	228	4	mt1	mt1	PROPN
dti-1352	228	5	and	and	CCONJ
dti-1352	228	6	mt2	mt2	ADJ
dti-1352	228	7	agonistic	agonistic	ADJ
dti-1352	228	8	properties	property	NOUN
dti-1352	228	9	of	of	ADP
dti-1352	228	10	agomelatine	agomelatine	NOUN
dti-1352	228	11	might	might	AUX
dti-1352	228	12	also	also	ADV
dti-1352	228	13	play	play	VERB
dti-1352	228	14	a	a	DET
dti-1352	228	15	role	role	NOUN
dti-1352	228	16	because	because	SCONJ
dti-1352	228	17	both	both	DET
dti-1352	228	18	receptors	receptor	NOUN
dti-1352	228	19	modulate	modulate	VERB
dti-1352	228	20	several	several	ADJ
dti-1352	228	21	signaling	signal	VERB
dti-1352	228	22	pathways	pathway	NOUN
dti-1352	228	23	such	such	ADJ
dti-1352	228	24	as	as	ADP
dti-1352	228	25	pka	pka	PROPN
dti-1352	228	26	and	and	CCONJ
dti-1352	228	27	protein	protein	NOUN
dti-1352	228	28	kinase	kinase	PROPN
dti-1352	228	29	c	c	PROPN
dti-1352	228	30	(	(	PUNCT
dti-1352	228	31	pkc	pkc	PROPN
dti-1352	228	32	)	)	PUNCT
dti-1352	228	33	,	,	PUNCT
dti-1352	228	34	which	which	PRON
dti-1352	228	35	have	have	AUX
dti-1352	228	36	been	be	AUX
dti-1352	228	37	implicated	implicate	VERB
dti-1352	228	38	in	in	ADP
dti-1352	228	39	synaptic	synaptic	ADJ
dti-1352	228	40	plasticity	plasticity	NOUN
dti-1352	228	41	regulation.40	regulation.40	NOUN
dti-1352	228	42	circadian	circadian	ADJ
dti-1352	228	43	rhythms	rhythm	NOUN
dti-1352	228	44	are	be	AUX
dti-1352	228	45	disturbed	disturb	VERB
dti-1352	228	46	in	in	ADP
dti-1352	228	47	depressed	depressed	ADJ
dti-1352	228	48	patients,44	patients,44	NOUN
dti-1352	228	49	and	and	CCONJ
dti-1352	228	50	the	the	DET
dti-1352	228	51	ucms	ucms	NOUN
dti-1352	228	52	procedure	procedure	NOUN
dti-1352	228	53	causes	cause	VERB
dti-1352	228	54	a	a	DET
dti-1352	228	55	generalized	generalized	ADJ
dti-1352	228	56	disorganization	disorganization	NOUN
dti-1352	228	57	of	of	ADP
dti-1352	228	58	circadian	circadian	ADJ
dti-1352	228	59	rhythms	rhythm	NOUN
dti-1352	228	60	,	,	PUNCT
dti-1352	228	61	which	which	PRON
dti-1352	228	62	is	be	AUX
dti-1352	228	63	suggested	suggest	VERB
dti-1352	228	64	to	to	PART
dti-1352	228	65	play	play	VERB
dti-1352	228	66	an	an	DET
dti-1352	228	67	important	important	ADJ
dti-1352	228	68	role	role	NOUN
dti-1352	228	69	in	in	ADP
dti-1352	228	70	the	the	DET
dti-1352	228	71	pathophysiology	pathophysiology	NOUN
dti-1352	228	72	of	of	ADP
dti-1352	228	73	depression	depression	NOUN
dti-1352	228	74	,	,	PUNCT
dti-1352	228	75	among	among	ADP
dti-1352	228	76	other	other	ADJ
dti-1352	228	77	biochemical	biochemical	ADJ
dti-1352	228	78	,	,	PUNCT
dti-1352	228	79	physiological	physiological	ADJ
dti-1352	228	80	,	,	PUNCT
dti-1352	228	81	and	and	CCONJ
dti-1352	228	82	behavioral	behavioral	ADJ
dti-1352	228	83	impairments.45	impairments.45	NOUN
dti-1352	228	84	agomelatine	agomelatine	NOUN
dti-1352	228	85	can	can	AUX
dti-1352	228	86	resynchronize	resynchronize	VERB
dti-1352	228	87	experimentally	experimentally	ADV
dti-1352	228	88	disturbed	disturb	VERB
dti-1352	228	89	circadian	circadian	PROPN
dti-1352	228	90	rhythms,36	rhythms,36	NOUN
dti-1352	228	91	an	an	DET
dti-1352	228	92	effect	effect	NOUN
dti-1352	228	93	that	that	PRON
dti-1352	228	94	is	be	AUX
dti-1352	228	95	independent	independent	ADJ
dti-1352	228	96	of	of	ADP
dti-1352	228	97	the	the	DET
dti-1352	228	98	time	time	NOUN
dti-1352	228	99	of	of	ADP
dti-1352	228	100	administration.36	administration.36	NOUN
dti-1352	228	101	table	table	NOUN
dti-1352	228	102	2	2	NUM
dti-1352	228	103	.	.	PUNCT
dti-1352	228	104	gene	gene	NOUN
dti-1352	228	105	expression	expression	NOUN
dti-1352	228	106	levels	level	NOUN
dti-1352	228	107	in	in	ADP
dti-1352	228	108	ucmsexposed	ucmsexpose	VERB
dti-1352	228	109	mice	mouse	NOUN
dti-1352	228	110	and	and	CCONJ
dti-1352	228	111	effects	effect	NOUN
dti-1352	228	112	of	of	ADP
dti-1352	228	113	drugs	drug	NOUN
dti-1352	228	114	on	on	ADP
dti-1352	228	115	gene	gene	NOUN
dti-1352	228	116	expressions	expression	NOUN
dti-1352	228	117	in	in	ADP
dti-1352	228	118	ucmsexposed	ucmsexposed	ADJ
dti-1352	228	119	mice	mouse	NOUN
dti-1352	228	120	.	.	PUNCT
dti-1352	229	1	melatonin	melatonin	NOUN
dti-1352	229	2	(	(	PUNCT
dti-1352	229	3	10	10	NUM
dti-1352	229	4	mg	mg	NUM
dti-1352	229	5	/	/	SYM
dti-1352	229	6	kg	kg	NOUN
dti-1352	229	7	)	)	PUNCT
dti-1352	229	8	or	or	CCONJ
dti-1352	229	9	agomelatine	agomelatine	NOUN
dti-1352	229	10	(	(	PUNCT
dti-1352	229	11	10	10	NUM
dti-1352	229	12	mg	mg	NUM
dti-1352	229	13	/	/	SYM
dti-1352	229	14	kg	kg	PROPN
dti-1352	229	15	)	)	PUNCT
dti-1352	229	16	was	be	AUX
dti-1352	229	17	given	give	VERB
dti-1352	229	18	intraperitoneally	intraperitoneally	ADV
dti-1352	229	19	for	for	ADP
dti-1352	229	20	35	35	NUM
dti-1352	229	21	days	day	NOUN
dti-1352	229	22	to	to	ADP
dti-1352	229	23	mice	mouse	NOUN
dti-1352	229	24	subjected	subject	VERB
dti-1352	229	25	to	to	ADP
dti-1352	229	26	unpredictable	unpredictable	ADJ
dti-1352	229	27	chronic	chronic	ADJ
dti-1352	229	28	mild	mild	ADJ
dti-1352	229	29	stress	stress	NOUN
dti-1352	229	30	(	(	PUNCT
dti-1352	229	31	ucms	ucms	NOUN
dti-1352	229	32	)	)	PUNCT
dti-1352	229	33	(	(	PUNCT
dti-1352	229	34	n	n	NOUN
dti-1352	229	35	=	=	NOUN
dti-1352	229	36	 	 	SPACE
dti-1352	229	37	7	7	NUM
dti-1352	229	38	/	/	SYM
dti-1352	229	39	each	each	DET
dti-1352	229	40	group	group	NOUN
dti-1352	229	41	)	)	PUNCT
dti-1352	229	42	.	.	PUNCT
dti-1352	230	1	all	all	PRON
dti-1352	230	2	of	of	ADP
dti-1352	230	3	the	the	DET
dti-1352	230	4	treatments	treatment	NOUN
dti-1352	230	5	begun	begin	VERB
dti-1352	230	6	after	after	ADP
dti-1352	230	7	2	2	NUM
dti-1352	230	8	weeks	week	NOUN
dti-1352	230	9	of	of	ADP
dti-1352	230	10	stress	stress	NOUN
dti-1352	230	11	regimen	regiman	NOUN
dti-1352	230	12	and	and	CCONJ
dti-1352	230	13	were	be	AUX
dti-1352	230	14	administered	administer	VERB
dti-1352	230	15	during	during	ADP
dti-1352	230	16	5	5	NUM
dti-1352	230	17	weeks	week	NOUN
dti-1352	230	18	.	.	PUNCT
dti-1352	231	1	groups	group	NOUN
dti-1352	231	2	creb	creb	PROPN
dti-1352	231	3	bdnf	bdnf	PROPN
dti-1352	231	4	ucms	ucm	NOUN
dti-1352	231	5	+	+	CCONJ
dti-1352	231	6	vehicle	vehicle	NOUN
dti-1352	231	7	2,408	2,408	NUM
dti-1352	231	8	↓	↓	NOUN
dti-1352	231	9	1,208	1,208	NUM
dti-1352	231	10	↓	↓	NOUN
dti-1352	231	11	ucms	ucms	NOUN
dti-1352	231	12	+	+	CCONJ
dti-1352	231	13	melatonin	melatonin	NOUN
dti-1352	231	14	6,409	6,409	NUM
dti-1352	231	15	↑	↑	NOUN
dti-1352	231	16	1,164	1,164	NUM
dti-1352	231	17	↑	↑	NOUN
dti-1352	231	18	ucms	ucm	NOUN
dti-1352	231	19	+	+	CCONJ
dti-1352	231	20	agomelatine	agomelatine	PROPN
dti-1352	231	21	2,088	2,088	NUM
dti-1352	231	22	↑	↑	NOUN
dti-1352	231	23	1,060	1,060	NUM
dti-1352	231	24	↑	↑	NOUN
dti-1352	231	25	notes	note	VERB
dti-1352	231	26	:	:	PUNCT
dti-1352	231	27	 	 	SPACE
dti-1352	231	28	↓	↓	NOUN
dti-1352	231	29	,	,	PUNCT
dti-1352	231	30	decrease	decrease	NOUN
dti-1352	231	31	in	in	ADP
dti-1352	231	32	expression	expression	NOUN
dti-1352	231	33	.	.	PUNCT
dti-1352	232	1	↑	↑	NOUN
dti-1352	232	2	,	,	PUNCT
dti-1352	232	3	increase	increase	VERB
dti-1352	232	4	in	in	ADP
dti-1352	232	5	expression	expression	NOUN
dti-1352	232	6	.	.	PUNCT
dti-1352	233	1	abbreviations	abbreviation	NOUN
dti-1352	233	2	:	:	PUNCT
dti-1352	233	3	creb	creb	NOUN
dti-1352	233	4	,	,	PUNCT
dti-1352	233	5	cyclic	cyclic	ADJ
dti-1352	233	6	adenosine	adenosine	NOUN
dti-1352	233	7	monophosphate	monophosphate	NOUN
dti-1352	233	8	(	(	PUNCT
dti-1352	233	9	camp	camp	NOUN
dti-1352	233	10	)	)	PUNCT
dti-1352	233	11	response	response	NOUN
dti-1352	233	12	element	element	NOUN
dti-1352	233	13	binding	bind	VERB
dti-1352	233	14	protein	protein	NOUN
dti-1352	233	15	;	;	PUNCT
dti-1352	233	16	bdnf	bdnf	ADJ
dti-1352	233	17	,	,	PUNCT
dti-1352	233	18	brain	brain	NOUN
dti-1352	233	19	-	-	PUNCT
dti-1352	233	20	derived	derive	VERB
dti-1352	233	21	neurotrophic	neurotrophic	ADJ
dti-1352	233	22	factor	factor	NOUN
dti-1352	233	23	.	.	PUNCT
dti-1352	234	1	http://www.la-press.com	http://www.la-press.com	X
dti-1352	234	2	agomelatin	agomelatin	PROPN
dti-1352	234	3	improves	improve	VERB
dti-1352	234	4	memory	memory	NOUN
dti-1352	234	5	in	in	ADP
dti-1352	234	6	stress	stress	NOUN
dti-1352	234	7	exposed	expose	VERB
dti-1352	234	8	mice	mouse	NOUN
dti-1352	235	1	19drug	19drug	PRON
dti-1352	235	2	target	target	NOUN
dti-1352	235	3	insights	insight	VERB
dti-1352	235	4	2014:8	2014:8	NUM
dti-1352	235	5	basic	basic	ADJ
dti-1352	235	6	and	and	CCONJ
dti-1352	235	7	clinical	clinical	ADJ
dti-1352	235	8	studies	study	NOUN
dti-1352	235	9	provide	provide	VERB
dti-1352	235	10	evidence	evidence	NOUN
dti-1352	235	11	for	for	ADP
dti-1352	235	12	the	the	DET
dti-1352	235	13	neurotrophic	neurotrophic	ADJ
dti-1352	235	14	hypothesis	hypothesis	NOUN
dti-1352	235	15	of	of	ADP
dti-1352	235	16	depression	depression	NOUN
dti-1352	235	17	and	and	CCONJ
dti-1352	235	18	antidepressant	antidepressant	ADJ
dti-1352	235	19	activity.20	activity.20	NOUN
dti-1352	235	20	the	the	DET
dti-1352	235	21	neurotrophin	neurotrophin	PROPN
dti-1352	235	22	family	family	PROPN
dti-1352	235	23	member	member	NOUN
dti-1352	235	24	bdnf	bdnf	PROPN
dti-1352	235	25	is	be	AUX
dti-1352	235	26	involved	involve	VERB
dti-1352	235	27	in	in	ADP
dti-1352	235	28	neuronal	neuronal	ADJ
dti-1352	235	29	differentiation	differentiation	NOUN
dti-1352	235	30	and	and	CCONJ
dti-1352	235	31	survival	survival	NOUN
dti-1352	235	32	as	as	ADV
dti-1352	235	33	well	well	ADV
dti-1352	235	34	as	as	ADP
dti-1352	235	35	the	the	DET
dti-1352	235	36	synaptic	synaptic	ADJ
dti-1352	235	37	plasticity	plasticity	NOUN
dti-1352	235	38	associated	associate	VERB
dti-1352	235	39	with	with	ADP
dti-1352	235	40	learning	learning	NOUN
dti-1352	235	41	and	and	CCONJ
dti-1352	235	42	memory.46	memory.46	VERB
dti-1352	235	43	the	the	DET
dti-1352	235	44	camp	camp	NOUN
dti-1352	235	45	signaling	signal	VERB
dti-1352	235	46	pathway	pathway	NOUN
dti-1352	235	47	(	(	PUNCT
dti-1352	235	48	in	in	ADP
dti-1352	235	49	particular	particular	ADJ
dti-1352	235	50	,	,	PUNCT
dti-1352	235	51	the	the	DET
dti-1352	235	52	downstream	downstream	ADJ
dti-1352	235	53	effector	effector	NOUN
dti-1352	235	54	creb	creb	PROPN
dti-1352	235	55	)	)	PUNCT
dti-1352	235	56	has	have	AUX
dti-1352	235	57	also	also	ADV
dti-1352	235	58	been	be	AUX
dti-1352	235	59	shown	show	VERB
dti-1352	235	60	to	to	PART
dti-1352	235	61	play	play	VERB
dti-1352	235	62	an	an	DET
dti-1352	235	63	important	important	ADJ
dti-1352	235	64	role	role	NOUN
dti-1352	235	65	in	in	ADP
dti-1352	235	66	neuronal	neuronal	ADJ
dti-1352	235	67	and	and	CCONJ
dti-1352	235	68	synaptic	synaptic	ADJ
dti-1352	235	69	plasticity.47	plasticity.47	NOUN
dti-1352	235	70	therefore	therefore	ADV
dti-1352	235	71	,	,	PUNCT
dti-1352	235	72	decreased	decrease	VERB
dti-1352	235	73	expression	expression	NOUN
dti-1352	235	74	of	of	ADP
dti-1352	235	75	bdnf	bdnf	PROPN
dti-1352	235	76	or	or	CCONJ
dti-1352	235	77	creb	creb	NOUN
dti-1352	235	78	could	could	AUX
dti-1352	235	79	contribute	contribute	VERB
dti-1352	235	80	to	to	ADP
dti-1352	235	81	the	the	DET
dti-1352	235	82	atrophy	atrophy	NOUN
dti-1352	235	83	of	of	ADP
dti-1352	235	84	the	the	DET
dti-1352	235	85	hippocampus	hippocampus	NOUN
dti-1352	235	86	in	in	ADP
dti-1352	235	87	response	response	NOUN
dti-1352	235	88	to	to	ADP
dti-1352	235	89	stress	stress	NOUN
dti-1352	235	90	,	,	PUNCT
dti-1352	235	91	and	and	CCONJ
dti-1352	235	92	the	the	DET
dti-1352	235	93	upregulation	upregulation	NOUN
dti-1352	235	94	of	of	ADP
dti-1352	235	95	bdnf	bdnf	PROPN
dti-1352	235	96	and	and	CCONJ
dti-1352	235	97	creb	creb	NOUN
dti-1352	235	98	could	could	AUX
dti-1352	235	99	contribute	contribute	VERB
dti-1352	235	100	to	to	ADP
dti-1352	235	101	the	the	DET
dti-1352	235	102	action	action	NOUN
dti-1352	235	103	of	of	ADP
dti-1352	235	104	antidepressant	antidepressant	ADJ
dti-1352	235	105	therapy.48	therapy.48	NOUN
dti-1352	235	106	it	it	PRON
dti-1352	235	107	has	have	AUX
dti-1352	235	108	been	be	AUX
dti-1352	235	109	postulated	postulate	VERB
dti-1352	235	110	that	that	SCONJ
dti-1352	235	111	chronic	chronic	ADJ
dti-1352	235	112	stress	stress	NOUN
dti-1352	235	113	caused	cause	VERB
dti-1352	235	114	a	a	DET
dti-1352	235	115	downregulation	downregulation	NOUN
dti-1352	235	116	of	of	ADP
dti-1352	235	117	hippocampal	hippocampal	ADJ
dti-1352	235	118	bdnf	bdnf	ADJ
dti-1352	235	119	or	or	CCONJ
dti-1352	235	120	creb	creb	NOUN
dti-1352	235	121	levels	level	NOUN
dti-1352	235	122	and	and	CCONJ
dti-1352	235	123	that	that	SCONJ
dti-1352	235	124	this	this	DET
dti-1352	235	125	reduction	reduction	NOUN
dti-1352	235	126	could	could	AUX
dti-1352	235	127	be	be	AUX
dti-1352	235	128	upregulated	upregulate	VERB
dti-1352	235	129	through	through	ADP
dti-1352	235	130	antidepressant	antidepressant	ADJ
dti-1352	235	131	therapy.48	therapy.48	NOUN
dti-1352	235	132	moreover	moreover	ADV
dti-1352	235	133	,	,	PUNCT
dti-1352	235	134	molteni	molteni	PROPN
dti-1352	235	135	et	et	PROPN
dti-1352	235	136	al.49	al.49	ADV
dti-1352	235	137	demonstrated	demonstrate	VERB
dti-1352	235	138	that	that	SCONJ
dti-1352	235	139	acute	acute	PROPN
dti-1352	235	140	agomelatine	agomelatine	NOUN
dti-1352	235	141	treatment	treatment	NOUN
dti-1352	235	142	modulates	modulate	VERB
dti-1352	235	143	the	the	DET
dti-1352	235	144	expression	expression	NOUN
dti-1352	235	145	of	of	ADP
dti-1352	235	146	bdnf	bdnf	PROPN
dti-1352	235	147	through	through	ADP
dti-1352	235	148	a	a	DET
dti-1352	235	149	functional	functional	ADJ
dti-1352	235	150	interaction	interaction	NOUN
dti-1352	235	151	between	between	ADP
dti-1352	235	152	melatonergic	melatonergic	NOUN
dti-1352	235	153	mt1/	mt1/	PROPN
dti-1352	235	154	mt2	mt2	NOUN
dti-1352	235	155	and	and	CCONJ
dti-1352	235	156	serotonergic	serotonergic	ADJ
dti-1352	235	157	5	5	NUM
dti-1352	235	158	-	-	PUNCT
dti-1352	235	159	ht2c	ht2c	NOUN
dti-1352	235	160	receptors	receptor	NOUN
dti-1352	235	161	,	,	PUNCT
dti-1352	235	162	supporting	support	VERB
dti-1352	235	163	the	the	DET
dti-1352	235	164	concept	concept	NOUN
dti-1352	235	165	that	that	SCONJ
dti-1352	235	166	intracellular	intracellular	ADJ
dti-1352	235	167	events	event	NOUN
dti-1352	235	168	can	can	AUX
dti-1352	235	169	be	be	AUX
dti-1352	235	170	regulated	regulate	VERB
dti-1352	235	171	via	via	ADP
dti-1352	235	172	the	the	DET
dti-1352	235	173	synergistic	synergistic	ADJ
dti-1352	235	174	activity	activity	NOUN
dti-1352	235	175	of	of	ADP
dti-1352	235	176	different	different	ADJ
dti-1352	235	177	neuromodulatory	neuromodulatory	ADJ
dti-1352	235	178	systems	system	NOUN
dti-1352	235	179	.	.	PUNCT
dti-1352	236	1	our	our	PRON
dti-1352	236	2	results	result	NOUN
dti-1352	236	3	are	be	AUX
dti-1352	236	4	consistent	consistent	ADJ
dti-1352	236	5	with	with	ADP
dti-1352	236	6	this	this	DET
dti-1352	236	7	hypothesis	hypothesis	NOUN
dti-1352	236	8	and	and	CCONJ
dti-1352	236	9	demonstrate	demonstrate	VERB
dti-1352	236	10	that	that	SCONJ
dti-1352	236	11	agomelatine	agomelatine	PROPN
dti-1352	236	12	treatment	treatment	NOUN
dti-1352	236	13	improves	improve	VERB
dti-1352	236	14	ucms	ucms	NOUN
dti-1352	236	15	-	-	PUNCT
dti-1352	236	16	induced	induce	VERB
dti-1352	236	17	memory	memory	NOUN
dti-1352	236	18	deterioration	deterioration	NOUN
dti-1352	236	19	and	and	CCONJ
dti-1352	236	20	upregulates	upregulate	VERB
dti-1352	236	21	hippocampal	hippocampal	ADJ
dti-1352	236	22	creb	creb	NOUN
dti-1352	236	23	and	and	CCONJ
dti-1352	236	24	bdnf	bdnf	ADJ
dti-1352	236	25	gene	gene	NOUN
dti-1352	236	26	expression	expression	NOUN
dti-1352	236	27	levels	level	NOUN
dti-1352	236	28	.	.	PUNCT
dti-1352	237	1	bdnf	bdnf	PROPN
dti-1352	237	2	belongs	belong	VERB
dti-1352	237	3	to	to	ADP
dti-1352	237	4	the	the	DET
dti-1352	237	5	neurotrophic	neurotrophic	ADJ
dti-1352	237	6	factor	factor	NOUN
dti-1352	237	7	family	family	NOUN
dti-1352	237	8	and	and	CCONJ
dti-1352	237	9	plays	play	VERB
dti-1352	237	10	a	a	DET
dti-1352	237	11	crucial	crucial	ADJ
dti-1352	237	12	role	role	NOUN
dti-1352	237	13	in	in	ADP
dti-1352	237	14	the	the	DET
dti-1352	237	15	development	development	NOUN
dti-1352	237	16	,	,	PUNCT
dti-1352	237	17	regeneration	regeneration	NOUN
dti-1352	237	18	,	,	PUNCT
dti-1352	237	19	survival	survival	NOUN
dti-1352	237	20	,	,	PUNCT
dti-1352	237	21	and	and	CCONJ
dti-1352	237	22	maintenance	maintenance	NOUN
dti-1352	237	23	of	of	ADP
dti-1352	237	24	neuronal	neuronal	ADJ
dti-1352	237	25	function	function	NOUN
dti-1352	237	26	in	in	ADP
dti-1352	237	27	the	the	DET
dti-1352	237	28	central	central	ADJ
dti-1352	237	29	nervous	nervous	ADJ
dti-1352	237	30	system.16	system.16	NOUN
dti-1352	237	31	these	these	DET
dti-1352	237	32	neurotrophins	neurotrophin	NOUN
dti-1352	237	33	are	be	AUX
dti-1352	237	34	abundantly	abundantly	ADV
dti-1352	237	35	expressed	express	VERB
dti-1352	237	36	in	in	ADP
dti-1352	237	37	the	the	DET
dti-1352	237	38	hippocampus,50	hippocampus,50	NOUN
dti-1352	237	39	where	where	SCONJ
dti-1352	237	40	they	they	PRON
dti-1352	237	41	are	be	AUX
dti-1352	237	42	important	important	ADJ
dti-1352	237	43	modulators	modulator	NOUN
dti-1352	237	44	of	of	ADP
dti-1352	237	45	spatial	spatial	ADJ
dti-1352	237	46	learning51	learning51	NOUN
dti-1352	237	47	and	and	CCONJ
dti-1352	237	48	activity	activity	NOUN
dti-1352	237	49	-	-	PUNCT
dti-1352	237	50	dependent	dependent	ADJ
dti-1352	237	51	synaptic	synaptic	ADJ
dti-1352	237	52	plasticity	plasticity	NOUN
dti-1352	237	53	,	,	PUNCT
dti-1352	237	54	such	such	ADJ
dti-1352	237	55	as	as	ADP
dti-1352	237	56	long	long	ADJ
dti-1352	237	57	-	-	PUNCT
dti-1352	237	58	term	term	NOUN
dti-1352	237	59	potentiation.52	potentiation.52	ADV
dti-1352	237	60	moreover	moreover	ADV
dti-1352	237	61	,	,	PUNCT
dti-1352	237	62	bdnf	bdnf	PROPN
dti-1352	237	63	plays	play	VERB
dti-1352	237	64	an	an	DET
dti-1352	237	65	important	important	ADJ
dti-1352	237	66	role	role	NOUN
dti-1352	237	67	in	in	ADP
dti-1352	237	68	the	the	DET
dti-1352	237	69	formation	formation	NOUN
dti-1352	237	70	,	,	PUNCT
dti-1352	237	71	retention	retention	NOUN
dti-1352	237	72	,	,	PUNCT
dti-1352	237	73	and	and	CCONJ
dti-1352	237	74	recall	recall	NOUN
dti-1352	237	75	of	of	ADP
dti-1352	237	76	spatial	spatial	ADJ
dti-1352	237	77	memory	memory	NOUN
dti-1352	237	78	,	,	PUNCT
dti-1352	237	79	and	and	CCONJ
dti-1352	237	80	decreases	decrease	NOUN
dti-1352	237	81	in	in	ADP
dti-1352	237	82	bdnf	bdnf	ADJ
dti-1352	237	83	expression	expression	NOUN
dti-1352	237	84	result	result	NOUN
dti-1352	237	85	in	in	ADP
dti-1352	237	86	the	the	DET
dti-1352	237	87	impairment	impairment	NOUN
dti-1352	237	88	of	of	ADP
dti-1352	237	89	spatial	spatial	ADJ
dti-1352	237	90	learning	learning	NOUN
dti-1352	237	91	and	and	CCONJ
dti-1352	237	92	memory.53	memory.53	VERB
dti-1352	237	93	the	the	DET
dti-1352	237	94	results	result	NOUN
dti-1352	237	95	of	of	ADP
dti-1352	237	96	clinical	clinical	ADJ
dti-1352	237	97	studies	study	NOUN
dti-1352	237	98	have	have	AUX
dti-1352	237	99	shown	show	VERB
dti-1352	237	100	that	that	SCONJ
dti-1352	237	101	depressive	depressive	ADJ
dti-1352	237	102	patients	patient	NOUN
dti-1352	237	103	exhibit	exhibit	VERB
dti-1352	237	104	diminished	diminished	ADJ
dti-1352	237	105	plasma	plasma	NOUN
dti-1352	237	106	bdnf	bdnf	PROPN
dti-1352	237	107	levels	level	NOUN
dti-1352	237	108	and	and	CCONJ
dti-1352	237	109	that	that	SCONJ
dti-1352	237	110	antidepressant	antidepressant	ADJ
dti-1352	237	111	treatment	treatment	NOUN
dti-1352	237	112	increases	increase	VERB
dti-1352	237	113	plasma	plasma	NOUN
dti-1352	237	114	bdnf	bdnf	PROPN
dti-1352	237	115	levels.54	levels.54	PROPN
dti-1352	237	116	interestingly	interestingly	ADV
dti-1352	237	117	,	,	PUNCT
dti-1352	237	118	the	the	DET
dti-1352	237	119	expression	expression	NOUN
dti-1352	237	120	of	of	ADP
dti-1352	237	121	bdnf	bdnf	PROPN
dti-1352	237	122	is	be	AUX
dti-1352	237	123	also	also	ADV
dti-1352	237	124	influenced	influence	VERB
dti-1352	237	125	by	by	ADP
dti-1352	237	126	light	light	ADJ
dti-1352	237	127	and	and	CCONJ
dti-1352	237	128	dark	dark	ADJ
dti-1352	237	129	cycles	cycle	NOUN
dti-1352	237	130	in	in	ADP
dti-1352	237	131	rats55	rats55	NOUN
dti-1352	237	132	as	as	ADV
dti-1352	237	133	well	well	ADV
dti-1352	237	134	as	as	ADP
dti-1352	237	135	in	in	ADP
dti-1352	237	136	humans.19	humans.19	PRON
dti-1352	237	137	it	it	PRON
dti-1352	237	138	is	be	AUX
dti-1352	237	139	speculated	speculate	VERB
dti-1352	237	140	that	that	SCONJ
dti-1352	237	141	acute	acute	PROPN
dti-1352	237	142	agomelatine	agomelatine	NOUN
dti-1352	237	143	treatment	treatment	NOUN
dti-1352	237	144	can	can	AUX
dti-1352	237	145	upregulate	upregulate	VERB
dti-1352	237	146	the	the	DET
dti-1352	237	147	expression	expression	NOUN
dti-1352	237	148	of	of	ADP
dti-1352	237	149	bdnf	bdnf	PROPN
dti-1352	237	150	mrna	mrna	PROPN
dti-1352	237	151	levels	level	NOUN
dti-1352	237	152	in	in	ADP
dti-1352	237	153	the	the	DET
dti-1352	237	154	prefrontal	prefrontal	ADJ
dti-1352	237	155	cortex	cortex	NOUN
dti-1352	237	156	through	through	ADP
dti-1352	237	157	the	the	DET
dti-1352	237	158	functional	functional	ADJ
dti-1352	237	159	interaction	interaction	NOUN
dti-1352	237	160	between	between	ADP
dti-1352	237	161	melatonergic	melatonergic	NOUN
dti-1352	237	162	mt1	mt1	PROPN
dti-1352	237	163	/	/	SYM
dti-1352	237	164	mt2	mt2	ADJ
dti-1352	237	165	and	and	CCONJ
dti-1352	237	166	serotonergic	serotonergic	ADJ
dti-1352	237	167	5	5	NUM
dti-1352	237	168	-	-	PUNCT
dti-1352	237	169	ht2c	ht2c	NOUN
dti-1352	237	170	receptors,56	receptors,56	NOUN
dti-1352	237	171	thus	thus	ADV
dti-1352	237	172	preventing	prevent	VERB
dti-1352	237	173	the	the	DET
dti-1352	237	174	circadian	circadian	ADJ
dti-1352	237	175	downregulation	downregulation	NOUN
dti-1352	237	176	of	of	ADP
dti-1352	237	177	the	the	DET
dti-1352	237	178	neurotrophin	neurotrophin	PROPN
dti-1352	237	179	.	.	PUNCT
dti-1352	238	1	soumier	soumier	PROPN
dti-1352	238	2	et	et	PROPN
dti-1352	238	3	al.57	al.57	PROPN
dti-1352	238	4	postulated	postulate	VERB
dti-1352	238	5	that	that	SCONJ
dti-1352	238	6	agomelatine	agomelatine	PROPN
dti-1352	238	7	produced	produce	VERB
dti-1352	238	8	major	major	ADJ
dti-1352	238	9	transcriptional	transcriptional	ADJ
dti-1352	238	10	changes	change	NOUN
dti-1352	238	11	in	in	ADP
dti-1352	238	12	the	the	DET
dti-1352	238	13	hippocampus	hippocampus	NOUN
dti-1352	238	14	,	,	PUNCT
dti-1352	238	15	where	where	SCONJ
dti-1352	238	16	significant	significant	ADJ
dti-1352	238	17	upregulation	upregulation	NOUN
dti-1352	238	18	of	of	ADP
dti-1352	238	19	bdnf	bdnf	PROPN
dti-1352	238	20	was	be	AUX
dti-1352	238	21	observed	observe	VERB
dti-1352	238	22	.	.	PUNCT
dti-1352	239	1	moreover	moreover	ADV
dti-1352	239	2	,	,	PUNCT
dti-1352	239	3	the	the	DET
dti-1352	239	4	levels	level	NOUN
dti-1352	239	5	of	of	ADP
dti-1352	239	6	bdnf	bdnf	ADJ
dti-1352	239	7	protein	protein	NOUN
dti-1352	239	8	were	be	AUX
dti-1352	239	9	elevated	elevate	VERB
dti-1352	239	10	by	by	ADP
dti-1352	239	11	agomelatine	agomelatine	NOUN
dti-1352	239	12	in	in	ADP
dti-1352	239	13	both	both	CCONJ
dti-1352	239	14	the	the	DET
dti-1352	239	15	hippocampus	hippocampus	NOUN
dti-1352	239	16	and	and	CCONJ
dti-1352	239	17	the	the	DET
dti-1352	239	18	prefrontal	prefrontal	ADJ
dti-1352	239	19	cortex.58	cortex.58	NOUN
dti-1352	239	20	these	these	DET
dti-1352	239	21	findings	finding	NOUN
dti-1352	239	22	support	support	VERB
dti-1352	239	23	the	the	DET
dti-1352	239	24	hypothesis	hypothesis	NOUN
dti-1352	239	25	that	that	DET
dti-1352	239	26	alteration	alteration	NOUN
dti-1352	239	27	of	of	ADP
dti-1352	239	28	hippocampal	hippocampal	ADJ
dti-1352	239	29	bdnf	bdnf	ADJ
dti-1352	239	30	expression	expression	NOUN
dti-1352	239	31	is	be	AUX
dti-1352	239	32	correlated	correlate	VERB
dti-1352	239	33	with	with	ADP
dti-1352	239	34	antidepressant	antidepressant	ADJ
dti-1352	239	35	response	response	NOUN
dti-1352	239	36	in	in	ADP
dti-1352	239	37	the	the	DET
dti-1352	239	38	hippocampus.16	hippocampus.16	PROPN
dti-1352	239	39	chronic	chronic	ADJ
dti-1352	239	40	agomelatine	agomelatine	NOUN
dti-1352	239	41	treatment	treatment	NOUN
dti-1352	239	42	decreased	decrease	VERB
dti-1352	239	43	bdnf	bdnf	ADJ
dti-1352	239	44	expression	expression	NOUN
dti-1352	239	45	in	in	ADP
dti-1352	239	46	the	the	DET
dti-1352	239	47	amygdale	amygdale	NOUN
dti-1352	239	48	and	and	CCONJ
dti-1352	239	49	this	this	DET
dti-1352	239	50	effect	effect	NOUN
dti-1352	239	51	might	might	AUX
dti-1352	239	52	be	be	AUX
dti-1352	239	53	related	relate	VERB
dti-1352	239	54	to	to	ADP
dti-1352	239	55	a	a	DET
dti-1352	239	56	negative	negative	ADJ
dti-1352	239	57	feedback	feedback	NOUN
dti-1352	239	58	mechanism	mechanism	NOUN
dti-1352	239	59	in	in	ADP
dti-1352	239	60	response	response	NOUN
dti-1352	239	61	to	to	ADP
dti-1352	239	62	the	the	DET
dti-1352	239	63	high	high	ADJ
dti-1352	239	64	magnitude	magnitude	NOUN
dti-1352	239	65	of	of	ADP
dti-1352	239	66	neuronal	neuronal	ADJ
dti-1352	239	67	remodeling	remodeling	NOUN
dti-1352	239	68	or	or	CCONJ
dti-1352	239	69	to	to	ADP
dti-1352	239	70	a	a	DET
dti-1352	239	71	distinct	distinct	ADJ
dti-1352	239	72	and	and	CCONJ
dti-1352	239	73	yet	yet	ADV
dti-1352	239	74	unknown	unknown	ADJ
dti-1352	239	75	neurochemical	neurochemical	ADJ
dti-1352	239	76	event.57	event.57	PROPN
dti-1352	239	77	chronic	chronic	PROPN
dti-1352	239	78	agomelatine	agomelatine	NOUN
dti-1352	239	79	has	have	VERB
dti-1352	239	80	neurogenic	neurogenic	ADJ
dti-1352	239	81	effects	effect	NOUN
dti-1352	239	82	in	in	ADP
dti-1352	239	83	the	the	DET
dti-1352	239	84	hippocampus	hippocampus	NOUN
dti-1352	239	85	in	in	ADP
dti-1352	239	86	rats57	rats57	NOUN
dti-1352	239	87	and	and	CCONJ
dti-1352	239	88	a	a	DET
dti-1352	239	89	reversed	reverse	VERB
dti-1352	239	90	depressioninduced	depressioninduce	VERB
dti-1352	239	91	decrease	decrease	NOUN
dti-1352	239	92	in	in	ADP
dti-1352	239	93	neurogenesis.59	neurogenesis.59	VERB
dti-1352	239	94	agomelatine	agomelatine	ADJ
dti-1352	239	95	exposure	exposure	NOUN
dti-1352	239	96	increases	increase	NOUN
dti-1352	239	97	neurite	neurite	VERB
dti-1352	239	98	outgrowth	outgrowth	NOUN
dti-1352	239	99	of	of	ADP
dti-1352	239	100	granule	granule	NOUN
dti-1352	239	101	cells	cell	NOUN
dti-1352	239	102	in	in	ADP
dti-1352	239	103	hippocampal	hippocampal	ADJ
dti-1352	239	104	primary	primary	ADJ
dti-1352	239	105	cell	cell	NOUN
dti-1352	239	106	culture	culture	NOUN
dti-1352	239	107	and	and	CCONJ
dti-1352	239	108	accelerates	accelerate	VERB
dti-1352	239	109	the	the	DET
dti-1352	239	110	maturation	maturation	NOUN
dti-1352	239	111	of	of	ADP
dti-1352	239	112	newly	newly	ADV
dti-1352	239	113	formed	form	VERB
dti-1352	239	114	granule	granule	NOUN
dti-1352	239	115	cells	cell	NOUN
dti-1352	239	116	in	in	ADP
dti-1352	239	117	rats.57	rats.57	PROPN
dti-1352	239	118	the	the	DET
dti-1352	239	119	results	result	NOUN
dti-1352	239	120	of	of	ADP
dti-1352	239	121	our	our	PRON
dti-1352	239	122	study	study	NOUN
dti-1352	239	123	revealed	reveal	VERB
dti-1352	239	124	that	that	SCONJ
dti-1352	239	125	chronic	chronic	ADJ
dti-1352	239	126	agomelatine	agomelatine	NOUN
dti-1352	239	127	increased	increase	VERB
dti-1352	239	128	bdnf	bdnf	ADJ
dti-1352	239	129	expression	expression	NOUN
dti-1352	239	130	in	in	ADP
dti-1352	239	131	the	the	DET
dti-1352	239	132	hippocampus	hippocampus	NOUN
dti-1352	239	133	,	,	PUNCT
dti-1352	239	134	and	and	CCONJ
dti-1352	239	135	our	our	PRON
dti-1352	239	136	findings	finding	NOUN
dti-1352	239	137	are	be	AUX
dti-1352	239	138	consistent	consistent	ADJ
dti-1352	239	139	with	with	ADP
dti-1352	239	140	those	those	PRON
dti-1352	239	141	of	of	ADP
dti-1352	239	142	recent	recent	ADJ
dti-1352	239	143	studies.57,60	studies.57,60	NOUN
dti-1352	239	144	these	these	DET
dti-1352	239	145	findings	finding	NOUN
dti-1352	239	146	provide	provide	VERB
dti-1352	239	147	new	new	ADJ
dti-1352	239	148	information	information	NOUN
dti-1352	239	149	regarding	regard	VERB
dti-1352	239	150	the	the	DET
dti-1352	239	151	molecular	molecular	ADJ
dti-1352	239	152	mechanisms	mechanism	NOUN
dti-1352	239	153	that	that	PRON
dti-1352	239	154	contribute	contribute	VERB
dti-1352	239	155	to	to	ADP
dti-1352	239	156	the	the	DET
dti-1352	239	157	chronic	chronic	ADJ
dti-1352	239	158	effects	effect	NOUN
dti-1352	239	159	of	of	ADP
dti-1352	239	160	the	the	DET
dti-1352	239	161	new	new	ADJ
dti-1352	239	162	antidepressant	antidepressant	ADJ
dti-1352	239	163	agomelatine	agomelatine	NOUN
dti-1352	239	164	on	on	ADP
dti-1352	239	165	brain	brain	NOUN
dti-1352	239	166	function	function	NOUN
dti-1352	239	167	.	.	PUNCT
dti-1352	240	1	the	the	DET
dti-1352	240	2	ability	ability	NOUN
dti-1352	240	3	of	of	ADP
dti-1352	240	4	agomelatine	agomelatine	NOUN
dti-1352	240	5	to	to	PART
dti-1352	240	6	modulate	modulate	VERB
dti-1352	240	7	the	the	DET
dti-1352	240	8	expression	expression	NOUN
dti-1352	240	9	of	of	ADP
dti-1352	240	10	these	these	DET
dti-1352	240	11	neuroplastic	neuroplastic	ADJ
dti-1352	240	12	molecules	molecule	NOUN
dti-1352	240	13	,	,	PUNCT
dti-1352	240	14	which	which	PRON
dti-1352	240	15	follow	follow	VERB
dti-1352	240	16	a	a	DET
dti-1352	240	17	circadian	circadian	ADJ
dti-1352	240	18	rhythm	rhythm	NOUN
dti-1352	240	19	,	,	PUNCT
dti-1352	240	20	may	may	AUX
dti-1352	240	21	contribute	contribute	VERB
dti-1352	240	22	to	to	ADP
dti-1352	240	23	its	its	PRON
dti-1352	240	24	antidepressant	antidepressant	ADJ
dti-1352	240	25	action	action	NOUN
dti-1352	240	26	.	.	PUNCT
dti-1352	241	1	bdnf	bdnf	PROPN
dti-1352	241	2	is	be	AUX
dti-1352	241	3	involved	involve	VERB
dti-1352	241	4	in	in	ADP
dti-1352	241	5	the	the	DET
dti-1352	241	6	etiology	etiology	NOUN
dti-1352	241	7	of	of	ADP
dti-1352	241	8	mood	mood	NOUN
dti-1352	241	9	disorders	disorder	NOUN
dti-1352	241	10	,	,	PUNCT
dti-1352	241	11	and	and	CCONJ
dti-1352	241	12	it	it	PRON
dti-1352	241	13	is	be	AUX
dti-1352	241	14	thought	think	VERB
dti-1352	241	15	to	to	PART
dti-1352	241	16	participate	participate	VERB
dti-1352	241	17	in	in	ADP
dti-1352	241	18	the	the	DET
dti-1352	241	19	structural	structural	ADJ
dti-1352	241	20	remodeling	remodeling	NOUN
dti-1352	241	21	associated	associate	VERB
dti-1352	241	22	with	with	ADP
dti-1352	241	23	antidepressant	antidepressant	ADJ
dti-1352	241	24	therapy.58	therapy.58	NOUN
dti-1352	241	25	as	as	ADP
dti-1352	241	26	neurotrophin	neurotrophin	ADJ
dti-1352	241	27	expression	expression	NOUN
dti-1352	241	28	is	be	AUX
dti-1352	241	29	activity	activity	NOUN
dti-1352	241	30	-	-	PUNCT
dti-1352	241	31	dependent17	dependent17	NOUN
dti-1352	241	32	and	and	CCONJ
dti-1352	241	33	may	may	AUX
dti-1352	241	34	be	be	AUX
dti-1352	241	35	regulated	regulate	VERB
dti-1352	241	36	by	by	ADP
dti-1352	241	37	the	the	DET
dti-1352	241	38	light	light	ADJ
dti-1352	241	39	and	and	CCONJ
dti-1352	241	40	dark	dark	ADJ
dti-1352	241	41	cycle	cycle	NOUN
dti-1352	241	42	in	in	ADP
dti-1352	241	43	rats18	rats18	NOUN
dti-1352	241	44	and	and	CCONJ
dti-1352	241	45	humans,19	humans,19	NOUN
dti-1352	241	46	it	it	PRON
dti-1352	241	47	may	may	AUX
dti-1352	241	48	be	be	AUX
dti-1352	241	49	inferred	infer	VERB
dti-1352	241	50	that	that	SCONJ
dti-1352	241	51	its	its	PRON
dti-1352	241	52	transcription	transcription	NOUN
dti-1352	241	53	can	can	AUX
dti-1352	241	54	be	be	AUX
dti-1352	241	55	modulated	modulate	VERB
dti-1352	241	56	by	by	ADP
dti-1352	241	57	acute	acute	PROPN
dti-1352	241	58	agomelatine	agomelatine	PROPN
dti-1352	241	59	administration	administration	NOUN
dti-1352	241	60	and	and	CCONJ
dti-1352	241	61	may	may	AUX
dti-1352	241	62	represent	represent	VERB
dti-1352	241	63	a	a	DET
dti-1352	241	64	downstream	downstream	ADJ
dti-1352	241	65	target	target	NOUN
dti-1352	241	66	of	of	ADP
dti-1352	241	67	its	its	PRON
dti-1352	241	68	synaptic	synaptic	ADJ
dti-1352	241	69	effects	effect	NOUN
dti-1352	241	70	.	.	PUNCT
dti-1352	242	1	on	on	ADP
dti-1352	242	2	this	this	DET
dti-1352	242	3	basis	basis	NOUN
dti-1352	242	4	,	,	PUNCT
dti-1352	242	5	we	we	PRON
dti-1352	242	6	investigated	investigate	VERB
dti-1352	242	7	bdnf	bdnf	PROPN
dti-1352	242	8	mrna	mrna	PROPN
dti-1352	242	9	levels	level	NOUN
dti-1352	242	10	in	in	ADP
dti-1352	242	11	the	the	DET
dti-1352	242	12	rat	rat	NOUN
dti-1352	242	13	hippocampus	hippocampus	NOUN
dti-1352	242	14	.	.	PUNCT
dti-1352	243	1	the	the	DET
dti-1352	243	2	camp	camp	NOUN
dti-1352	243	3	-	-	PUNCT
dti-1352	243	4	creb	creb	NOUN
dti-1352	243	5	signal	signal	NOUN
dti-1352	243	6	transduction	transduction	NOUN
dti-1352	243	7	cascade	cascade	NOUN
dti-1352	243	8	is	be	AUX
dti-1352	243	9	known	know	VERB
dti-1352	243	10	to	to	PART
dti-1352	243	11	be	be	AUX
dti-1352	243	12	responsible	responsible	ADJ
dti-1352	243	13	for	for	ADP
dti-1352	243	14	the	the	DET
dti-1352	243	15	sustained	sustained	ADJ
dti-1352	243	16	alterations	alteration	NOUN
dti-1352	243	17	that	that	PRON
dti-1352	243	18	occur	occur	VERB
dti-1352	243	19	in	in	ADP
dti-1352	243	20	cellular	cellular	ADJ
dti-1352	243	21	and	and	CCONJ
dti-1352	243	22	behavioral	behavioral	ADJ
dti-1352	243	23	models	model	NOUN
dti-1352	243	24	of	of	ADP
dti-1352	243	25	learning	learning	NOUN
dti-1352	243	26	and	and	CCONJ
dti-1352	243	27	memory.61	memory.61	NOUN
dti-1352	243	28	chronic	chronic	NOUN
dti-1352	243	29	but	but	CCONJ
dti-1352	243	30	not	not	PART
dti-1352	243	31	acute	acute	ADJ
dti-1352	243	32	antidepressant	antidepressant	ADJ
dti-1352	243	33	administration	administration	NOUN
dti-1352	243	34	,	,	PUNCT
dti-1352	243	35	including	include	VERB
dti-1352	243	36	norepinephrine	norepinephrine	NOUN
dti-1352	243	37	and	and	CCONJ
dti-1352	243	38	selective	selective	ADJ
dti-1352	243	39	serotonin	serotonin	NOUN
dti-1352	243	40	reuptake	reuptake	NOUN
dti-1352	243	41	inhibitors	inhibitor	NOUN
dti-1352	243	42	,	,	PUNCT
dti-1352	243	43	increases	increase	VERB
dti-1352	243	44	creb	creb	NOUN
dti-1352	243	45	expression	expression	NOUN
dti-1352	243	46	,	,	PUNCT
dti-1352	243	47	phosphorylation	phosphorylation	NOUN
dti-1352	243	48	,	,	PUNCT
dti-1352	243	49	and	and	CCONJ
dti-1352	243	50	function	function	NOUN
dti-1352	243	51	in	in	ADP
dti-1352	243	52	limbic	limbic	ADJ
dti-1352	243	53	brain	brain	NOUN
dti-1352	243	54	structures	structure	NOUN
dti-1352	243	55	including	include	VERB
dti-1352	243	56	the	the	DET
dti-1352	243	57	hippocampus	hippocampus	NOUN
dti-1352	243	58	and	and	CCONJ
dti-1352	243	59	cerebral	cerebral	ADJ
dti-1352	243	60	cortex.62	cortex.62	PROPN
dti-1352	243	61	agomelatine	agomelatine	NOUN
dti-1352	243	62	has	have	VERB
dti-1352	243	63	a	a	DET
dti-1352	243	64	favorable	favorable	ADJ
dti-1352	243	65	clinical	clinical	ADJ
dti-1352	243	66	safety	safety	NOUN
dti-1352	243	67	and	and	CCONJ
dti-1352	243	68	tolerability	tolerability	NOUN
dti-1352	243	69	profile	profile	NOUN
dti-1352	243	70	of	of	ADP
dti-1352	243	71	antidepressant	antidepressant	ADJ
dti-1352	243	72	properties	property	NOUN
dti-1352	243	73	with	with	ADP
dti-1352	243	74	few	few	ADJ
dti-1352	243	75	side	side	NOUN
dti-1352	243	76	effects	effect	NOUN
dti-1352	243	77	and	and	CCONJ
dti-1352	243	78	no	no	DET
dti-1352	243	79	withdrawal	withdrawal	NOUN
dti-1352	243	80	syndrome.11	syndrome.11	VERB
dti-1352	243	81	in	in	ADP
dti-1352	243	82	contrast	contrast	NOUN
dti-1352	243	83	to	to	ADP
dti-1352	243	84	ssris,63	ssris,63	NOUN
dti-1352	243	85	it	it	PRON
dti-1352	243	86	has	have	VERB
dti-1352	243	87	few	few	ADJ
dti-1352	243	88	sexual	sexual	ADJ
dti-1352	243	89	side	side	NOUN
dti-1352	243	90	effects	effect	NOUN
dti-1352	243	91	and	and	CCONJ
dti-1352	243	92	there	there	PRON
dti-1352	243	93	are	be	VERB
dti-1352	243	94	no	no	DET
dti-1352	243	95	reports	report	NOUN
dti-1352	243	96	of	of	ADP
dti-1352	243	97	impotence	impotence	NOUN
dti-1352	243	98	,	,	PUNCT
dti-1352	243	99	ejaculation	ejaculation	NOUN
dti-1352	243	100	difficulties	difficulty	NOUN
dti-1352	243	101	,	,	PUNCT
dti-1352	243	102	or	or	CCONJ
dti-1352	243	103	decreased	decrease	VERB
dti-1352	243	104	libido	libido	NOUN
dti-1352	243	105	.	.	PUNCT
dti-1352	244	1	the	the	DET
dti-1352	244	2	novel	novel	ADJ
dti-1352	244	3	mode	mode	NOUN
dti-1352	244	4	of	of	ADP
dti-1352	244	5	action	action	NOUN
dti-1352	244	6	of	of	ADP
dti-1352	244	7	agomelatine	agomelatine	NOUN
dti-1352	244	8	(	(	PUNCT
dti-1352	244	9	selective	selective	ADJ
dti-1352	244	10	binding	bind	VERB
dti-1352	244	11	profile	profile	NOUN
dti-1352	244	12	,	,	PUNCT
dti-1352	244	13	not	not	PART
dti-1352	244	14	inducing	induce	VERB
dti-1352	244	15	serotonin	serotonin	NOUN
dti-1352	244	16	release	release	NOUN
dti-1352	244	17	or	or	CCONJ
dti-1352	244	18	increasing	increase	VERB
dti-1352	244	19	extracellular	extracellular	ADJ
dti-1352	244	20	serotonin	serotonin	NOUN
dti-1352	244	21	levels	level	NOUN
dti-1352	244	22	and	and	CCONJ
dti-1352	244	23	no	no	DET
dti-1352	244	24	effect	effect	NOUN
dti-1352	244	25	on	on	ADP
dti-1352	244	26	5	5	NUM
dti-1352	244	27	-	-	NUM
dti-1352	244	28	ht1	ht1	NOUN
dti-1352	244	29	a	a	DET
dti-1352	244	30	receptors)7	receptors)7	PROPN
dti-1352	244	31	might	might	AUX
dti-1352	244	32	be	be	AUX
dti-1352	244	33	responsible	responsible	ADJ
dti-1352	244	34	for	for	ADP
dti-1352	244	35	its	its	PRON
dti-1352	244	36	favorable	favorable	ADJ
dti-1352	244	37	safety	safety	NOUN
dti-1352	244	38	profile	profile	NOUN
dti-1352	244	39	.	.	PUNCT
dti-1352	245	1	overall	overall	ADV
dti-1352	245	2	,	,	PUNCT
dti-1352	245	3	the	the	DET
dti-1352	245	4	present	present	ADJ
dti-1352	245	5	study	study	NOUN
dti-1352	245	6	suggests	suggest	VERB
dti-1352	245	7	that	that	SCONJ
dti-1352	245	8	chronic	chronic	ADJ
dti-1352	245	9	administration	administration	NOUN
dti-1352	245	10	of	of	ADP
dti-1352	245	11	the	the	DET
dti-1352	245	12	novel	novel	ADJ
dti-1352	245	13	antidepressant	antidepressant	ADJ
dti-1352	245	14	agomelatine	agomelatine	NOUN
dti-1352	245	15	,	,	PUNCT
dti-1352	245	16	with	with	ADP
dti-1352	245	17	its	its	PRON
dti-1352	245	18	distinct	distinct	ADJ
dti-1352	245	19	mechanism	mechanism	NOUN
dti-1352	245	20	of	of	ADP
dti-1352	245	21	action	action	NOUN
dti-1352	245	22	based	base	VERB
dti-1352	245	23	on	on	ADP
dti-1352	245	24	synergy	synergy	NOUN
dti-1352	245	25	between	between	ADP
dti-1352	245	26	the	the	DET
dti-1352	245	27	melatonergic	melatonergic	NOUN
dti-1352	245	28	and	and	CCONJ
dti-1352	245	29	5	5	NUM
dti-1352	245	30	-	-	PUNCT
dti-1352	245	31	ht2c	ht2c	NOUN
dti-1352	245	32	pathways	pathway	NOUN
dti-1352	245	33	and	and	CCONJ
dti-1352	245	34	the	the	DET
dti-1352	245	35	advantages	advantage	NOUN
dti-1352	245	36	of	of	ADP
dti-1352	245	37	a	a	DET
dti-1352	245	38	favorable	favorable	ADJ
dti-1352	245	39	clinical	clinical	ADJ
dti-1352	245	40	safety	safety	NOUN
dti-1352	245	41	/	/	SYM
dti-1352	245	42	tolerability	tolerability	NOUN
dti-1352	245	43	profile	profile	NOUN
dti-1352	245	44	,	,	PUNCT
dti-1352	245	45	improves	improve	VERB
dti-1352	245	46	memory	memory	NOUN
dti-1352	245	47	deterioration	deterioration	NOUN
dti-1352	245	48	and	and	CCONJ
dti-1352	245	49	upregulates	upregulate	VERB
dti-1352	245	50	creb	creb	NOUN
dti-1352	245	51	and	and	CCONJ
dti-1352	245	52	bdnf	bdnf	ADJ
dti-1352	245	53	gene	gene	NOUN
dti-1352	245	54	expression	expression	NOUN
dti-1352	245	55	levels	level	NOUN
dti-1352	245	56	in	in	ADP
dti-1352	245	57	ucms	ucms	NOUN
dti-1352	245	58	-	-	PUNCT
dti-1352	245	59	exposed	expose	VERB
dti-1352	245	60	mice	mouse	NOUN
dti-1352	245	61	.	.	PUNCT
dti-1352	246	1	thus	thus	ADV
dti-1352	246	2	,	,	PUNCT
dti-1352	246	3	agomelatine	agomelatine	PROPN
dti-1352	246	4	appears	appear	VERB
dti-1352	246	5	to	to	PART
dti-1352	246	6	play	play	VERB
dti-1352	246	7	an	an	DET
dti-1352	246	8	important	important	ADJ
dti-1352	246	9	role	role	NOUN
dti-1352	246	10	in	in	ADP
dti-1352	246	11	blocking	block	VERB
dti-1352	246	12	stress	stress	NOUN
dti-1352	246	13	-	-	PUNCT
dti-1352	246	14	induced	induce	VERB
dti-1352	246	15	hippocampal	hippocampal	ADJ
dti-1352	246	16	memory	memory	NOUN
dti-1352	246	17	deterioration	deterioration	NOUN
dti-1352	246	18	and	and	CCONJ
dti-1352	246	19	activates	activate	VERB
dti-1352	246	20	the	the	DET
dti-1352	246	21	molecular	molecular	ADJ
dti-1352	246	22	mechanisms	mechanism	NOUN
dti-1352	246	23	of	of	ADP
dti-1352	246	24	memory	memory	NOUN
dti-1352	246	25	storage	storage	NOUN
dti-1352	246	26	in	in	ADP
dti-1352	246	27	response	response	NOUN
dti-1352	246	28	to	to	ADP
dti-1352	246	29	a	a	DET
dti-1352	246	30	learning	learning	NOUN
dti-1352	246	31	experience	experience	NOUN
dti-1352	246	32	.	.	PUNCT
dti-1352	247	1	http://www.la-press.com	http://www.la-press.com	X
dti-1352	248	1	gumuslu	gumuslu	PROPN
dti-1352	248	2	et	et	PROPN
dti-1352	248	3	al	al	PROPN
dti-1352	248	4	20	20	NUM
dti-1352	248	5	drug	drug	NOUN
dti-1352	248	6	target	target	NOUN
dti-1352	248	7	insights	insight	VERB
dti-1352	248	8	2014:8	2014:8	NUM
dti-1352	248	9	author	author	NOUN
dti-1352	248	10	contributions	contribution	NOUN
dti-1352	248	11	eg	eg	NOUN
dti-1352	248	12	,	,	PUNCT
dti-1352	248	13	om	om	PROPN
dti-1352	248	14	,	,	PUNCT
dti-1352	248	15	ds	ds	ADJ
dti-1352	248	16	,	,	PUNCT
dti-1352	248	17	and	and	CCONJ
dti-1352	248	18	gu	gu	NOUN
dti-1352	248	19	conceived	conceive	VERB
dti-1352	248	20	and	and	CCONJ
dti-1352	248	21	designed	design	VERB
dti-1352	248	22	the	the	DET
dti-1352	248	23	experiments	experiment	NOUN
dti-1352	248	24	.	.	PUNCT
dti-1352	249	1	eg	eg	NOUN
dti-1352	249	2	,	,	PUNCT
dti-1352	249	3	om	om	PROPN
dti-1352	249	4	,	,	PUNCT
dti-1352	249	5	ds	ds	ADJ
dti-1352	249	6	,	,	PUNCT
dti-1352	249	7	ikc	ikc	NOUN
dti-1352	249	8	,	,	PUNCT
dti-1352	249	9	and	and	CCONJ
dti-1352	249	10	nc	nc	PROPN
dti-1352	249	11	analyzed	analyze	VERB
dti-1352	249	12	the	the	DET
dti-1352	249	13	data	datum	NOUN
dti-1352	249	14	.	.	PUNCT
dti-1352	250	1	eg	eg	NOUN
dti-1352	250	2	,	,	PUNCT
dti-1352	250	3	om	om	PROPN
dti-1352	250	4	,	,	PUNCT
dti-1352	250	5	gu	gu	NOUN
dti-1352	250	6	,	,	PUNCT
dti-1352	250	7	and	and	CCONJ
dti-1352	250	8	ikc	ikc	PROPN
dti-1352	250	9	wrote	write	VERB
dti-1352	250	10	the	the	DET
dti-1352	250	11	first	first	ADJ
dti-1352	250	12	draft	draft	NOUN
dti-1352	250	13	of	of	ADP
dti-1352	250	14	the	the	DET
dti-1352	250	15	manuscript	manuscript	NOUN
dti-1352	250	16	.	.	PUNCT
dti-1352	251	1	nc	nc	PROPN
dti-1352	251	2	,	,	PUNCT
dti-1352	251	3	fa	fa	PROPN
dti-1352	251	4	,	,	PUNCT
dti-1352	251	5	hs	hs	PROPN
dti-1352	251	6	,	,	PUNCT
dti-1352	251	7	and	and	CCONJ
dti-1352	251	8	fe	fe	NOUN
dti-1352	251	9	contributed	contribute	VERB
dti-1352	251	10	to	to	ADP
dti-1352	251	11	the	the	DET
dti-1352	251	12	writing	writing	NOUN
dti-1352	251	13	of	of	ADP
dti-1352	251	14	the	the	DET
dti-1352	251	15	manuscript	manuscript	NOUN
dti-1352	251	16	.	.	PUNCT
dti-1352	252	1	eg	eg	NOUN
dti-1352	252	2	,	,	PUNCT
dti-1352	252	3	om	om	PROPN
dti-1352	252	4	,	,	PUNCT
dti-1352	252	5	ds	ds	PROPN
dti-1352	252	6	,	,	PUNCT
dti-1352	252	7	gu	gu	NOUN
dti-1352	252	8	,	,	PUNCT
dti-1352	252	9	ikc	ikc	PROPN
dti-1352	252	10	,	,	PUNCT
dti-1352	252	11	nc	nc	PROPN
dti-1352	252	12	,	,	PUNCT
dti-1352	252	13	fa	fa	PROPN
dti-1352	252	14	,	,	PUNCT
dti-1352	252	15	hs	hs	PROPN
dti-1352	252	16	,	,	PUNCT
dti-1352	252	17	and	and	CCONJ
dti-1352	252	18	fe	fe	X
dti-1352	252	19	agree	agree	VERB
dti-1352	252	20	with	with	ADP
dti-1352	252	21	manuscript	manuscript	NOUN
dti-1352	252	22	results	result	NOUN
dti-1352	252	23	and	and	CCONJ
dti-1352	252	24	conclusions	conclusion	NOUN
dti-1352	252	25	.	.	PUNCT
dti-1352	253	1	eg	eg	NOUN
dti-1352	253	2	,	,	PUNCT
dti-1352	253	3	om	om	PROPN
dti-1352	253	4	,	,	PUNCT
dti-1352	253	5	gu	gu	NOUN
dti-1352	253	6	,	,	PUNCT
dti-1352	253	7	fa	fa	PROPN
dti-1352	253	8	,	,	PUNCT
dti-1352	253	9	hs	hs	PROPN
dti-1352	253	10	,	,	PUNCT
dti-1352	253	11	and	and	CCONJ
dti-1352	253	12	fe	fe	NOUN
dti-1352	253	13	jointly	jointly	ADV
dti-1352	253	14	developed	develop	VERB
dti-1352	253	15	the	the	DET
dti-1352	253	16	structure	structure	NOUN
dti-1352	253	17	and	and	CCONJ
dti-1352	253	18	arguments	argument	NOUN
dti-1352	253	19	for	for	ADP
dti-1352	253	20	the	the	DET
dti-1352	253	21	paper	paper	NOUN
dti-1352	253	22	.	.	PUNCT
dti-1352	254	1	fa	fa	PROPN
dti-1352	254	2	,	,	PUNCT
dti-1352	254	3	hs	hs	PROPN
dti-1352	254	4	,	,	PUNCT
dti-1352	254	5	and	and	CCONJ
dti-1352	254	6	fe	fe	NOUN
dti-1352	254	7	made	make	VERB
dti-1352	254	8	critical	critical	ADJ
dti-1352	254	9	revisions	revision	NOUN
dti-1352	254	10	and	and	CCONJ
dti-1352	254	11	approved	approve	VERB
dti-1352	254	12	final	final	ADJ
dti-1352	254	13	version	version	NOUN
dti-1352	254	14	.	.	PUNCT
dti-1352	255	1	all	all	DET
dti-1352	255	2	authors	author	NOUN
dti-1352	255	3	reviewed	review	VERB
dti-1352	255	4	and	and	CCONJ
dti-1352	255	5	approved	approve	VERB
dti-1352	255	6	the	the	DET
dti-1352	255	7	final	final	ADJ
dti-1352	255	8	manuscript	manuscript	NOUN
dti-1352	255	9	.	.	PUNCT
dti-1352	256	1	disclosures	disclosure	NOUN
dti-1352	256	2	and	and	CCONJ
dti-1352	256	3	ethics	ethic	NOUN
dti-1352	256	4	as	as	ADP
dti-1352	256	5	a	a	DET
dti-1352	256	6	requirement	requirement	NOUN
dti-1352	256	7	of	of	ADP
dti-1352	256	8	publication	publication	NOUN
dti-1352	256	9	the	the	DET
dti-1352	256	10	authors	author	NOUN
dti-1352	256	11	have	have	AUX
dti-1352	256	12	provided	provide	VERB
dti-1352	256	13	signed	sign	VERB
dti-1352	256	14	confirmation	confirmation	NOUN
dti-1352	256	15	of	of	ADP
dti-1352	256	16	their	their	PRON
dti-1352	256	17	compliance	compliance	NOUN
dti-1352	256	18	with	with	ADP
dti-1352	256	19	ethical	ethical	ADJ
dti-1352	256	20	and	and	CCONJ
dti-1352	256	21	legal	legal	ADJ
dti-1352	256	22	obligations	obligation	NOUN
dti-1352	256	23	including	include	VERB
dti-1352	256	24	but	but	CCONJ
dti-1352	256	25	not	not	PART
dti-1352	256	26	limited	limit	VERB
dti-1352	256	27	to	to	ADP
dti-1352	256	28	compliance	compliance	NOUN
dti-1352	256	29	with	with	ADP
dti-1352	256	30	icmje	icmje	NOUN
dti-1352	256	31	authorship	authorship	NOUN
dti-1352	256	32	and	and	CCONJ
dti-1352	256	33	competing	compete	VERB
dti-1352	256	34	interests	interest	NOUN
dti-1352	256	35	guidelines	guideline	NOUN
dti-1352	256	36	,	,	PUNCT
dti-1352	256	37	that	that	SCONJ
dti-1352	256	38	the	the	DET
dti-1352	256	39	article	article	NOUN
dti-1352	256	40	is	be	AUX
dti-1352	256	41	neither	neither	CCONJ
dti-1352	256	42	under	under	ADP
dti-1352	256	43	consideration	consideration	NOUN
dti-1352	256	44	for	for	ADP
dti-1352	256	45	publication	publication	NOUN
dti-1352	256	46	nor	nor	CCONJ
dti-1352	256	47	published	publish	VERB
dti-1352	256	48	elsewhere	elsewhere	ADV
dti-1352	256	49	,	,	PUNCT
dti-1352	256	50	of	of	ADP
dti-1352	256	51	their	their	PRON
dti-1352	256	52	compliance	compliance	NOUN
dti-1352	256	53	with	with	ADP
dti-1352	256	54	legal	legal	ADJ
dti-1352	256	55	and	and	CCONJ
dti-1352	256	56	ethical	ethical	ADJ
dti-1352	256	57	guidelines	guideline	NOUN
dti-1352	256	58	concerning	concern	VERB
dti-1352	256	59	human	human	ADJ
dti-1352	256	60	and	and	CCONJ
dti-1352	256	61	animal	animal	NOUN
dti-1352	256	62	research	research	NOUN
dti-1352	256	63	participants	participant	NOUN
dti-1352	256	64	(	(	PUNCT
dti-1352	256	65	if	if	SCONJ
dti-1352	256	66	applicable	applicable	ADJ
dti-1352	256	67	)	)	PUNCT
dti-1352	256	68	,	,	PUNCT
dti-1352	256	69	and	and	CCONJ
dti-1352	256	70	that	that	DET
dti-1352	256	71	permission	permission	NOUN
dti-1352	256	72	has	have	AUX
dti-1352	256	73	been	be	AUX
dti-1352	256	74	obtained	obtain	VERB
dti-1352	256	75	for	for	ADP
dti-1352	256	76	reproduction	reproduction	NOUN
dti-1352	256	77	of	of	ADP
dti-1352	256	78	any	any	DET
dti-1352	256	79	copyrighted	copyright	VERB
dti-1352	256	80	material	material	NOUN
dti-1352	256	81	.	.	PUNCT
dti-1352	257	1	this	this	DET
dti-1352	257	2	article	article	NOUN
dti-1352	257	3	was	be	AUX
dti-1352	257	4	subject	subject	ADJ
dti-1352	257	5	to	to	ADP
dti-1352	257	6	blind	blind	ADJ
dti-1352	257	7	,	,	PUNCT
dti-1352	257	8	independent	independent	ADJ
dti-1352	257	9	,	,	PUNCT
dti-1352	257	10	expert	expert	ADJ
dti-1352	257	11	peer	peer	NOUN
dti-1352	257	12	review	review	NOUN
dti-1352	257	13	.	.	PUNCT
dti-1352	258	1	the	the	DET
dti-1352	258	2	reviewers	reviewer	NOUN
dti-1352	258	3	reported	report	VERB
dti-1352	258	4	no	no	DET
dti-1352	258	5	competing	compete	VERB
dti-1352	258	6	interests	interest	NOUN
dti-1352	258	7	.	.	PUNCT
dti-1352	259	1	references	reference	NOUN
dti-1352	259	2	1	1	NUM
dti-1352	259	3	.	.	PUNCT
dti-1352	260	1	yau	yau	PROPN
dti-1352	260	2	jl	jl	PROPN
dti-1352	260	3	,	,	PUNCT
dti-1352	260	4	noble	noble	ADJ
dti-1352	260	5	j	j	PROPN
dti-1352	260	6	,	,	PUNCT
dti-1352	260	7	hibberd	hibberd	NOUN
dti-1352	260	8	c	c	NOUN
dti-1352	260	9	,	,	PUNCT
dti-1352	260	10	et	et	PROPN
dti-1352	260	11	al	al	PROPN
dti-1352	260	12	.	.	PROPN
dti-1352	260	13	chronic	chronic	ADJ
dti-1352	260	14	treatment	treatment	NOUN
dti-1352	260	15	with	with	ADP
dti-1352	260	16	the	the	DET
dti-1352	260	17	antidepressant	antidepressant	ADJ
dti-1352	260	18	amitriptyline	amitriptyline	NOUN
dti-1352	260	19	prevents	prevent	VERB
dti-1352	260	20	impairments	impairment	NOUN
dti-1352	260	21	in	in	ADP
dti-1352	260	22	water	water	NOUN
dti-1352	260	23	maze	maze	NOUN
dti-1352	260	24	learning	learning	NOUN
dti-1352	260	25	in	in	ADP
dti-1352	260	26	aging	age	VERB
dti-1352	260	27	rats	rat	NOUN
dti-1352	260	28	.	.	PUNCT
dti-1352	261	1	j	j	PROPN
dti-1352	261	2	neurosci	neurosci	PROPN
dti-1352	261	3	.	.	PUNCT
dti-1352	262	1	2002;22:1436–42	2002;22:1436–42	NUM
dti-1352	262	2	.	.	NOUN
dti-1352	262	3	2	2	NUM
dti-1352	262	4	.	.	X
dti-1352	262	5	bremner	bremner	PROPN
dti-1352	262	6	jd	jd	PROPN
dti-1352	262	7	,	,	PUNCT
dti-1352	262	8	vermetten	vermetten	VERB
dti-1352	262	9	e.	e.	PROPN
dti-1352	262	10	stress	stress	PROPN
dti-1352	262	11	and	and	CCONJ
dti-1352	262	12	development	development	NOUN
dti-1352	262	13	:	:	PUNCT
dti-1352	262	14	behavioral	behavioral	ADJ
dti-1352	262	15	and	and	CCONJ
dti-1352	262	16	biological	biological	ADJ
dti-1352	262	17	consequences	consequence	NOUN
dti-1352	262	18	.	.	PUNCT
dti-1352	263	1	dev	dev	PROPN
dti-1352	263	2	psychopathol	psychopathol	NOUN
dti-1352	263	3	.	.	PUNCT
dti-1352	264	1	2001;13:473–89	2001;13:473–89	X
dti-1352	264	2	.	.	PUNCT
dti-1352	265	1	3	3	X
dti-1352	265	2	.	.	X
dti-1352	265	3	de	de	X
dti-1352	265	4	quervain	quervain	NOUN
dti-1352	265	5	dj	dj	PROPN
dti-1352	265	6	,	,	PUNCT
dti-1352	265	7	roozendaal	roozendaal	PROPN
dti-1352	265	8	b	b	PROPN
dti-1352	265	9	,	,	PUNCT
dti-1352	265	10	nitsch	nitsch	PROPN
dti-1352	265	11	rm	rm	PROPN
dti-1352	265	12	,	,	PUNCT
dti-1352	265	13	mcgaugh	mcgaugh	PROPN
dti-1352	265	14	jl	jl	PROPN
dti-1352	265	15	,	,	PUNCT
dti-1352	265	16	hock	hock	PROPN
dti-1352	265	17	c.	c.	PROPN
dti-1352	265	18	acute	acute	PROPN
dti-1352	265	19	cortisone	cortisone	PROPN
dti-1352	265	20	administration	administration	NOUN
dti-1352	265	21	impairs	impair	VERB
dti-1352	265	22	retrieval	retrieval	NOUN
dti-1352	265	23	of	of	ADP
dti-1352	265	24	long	long	ADJ
dti-1352	265	25	-	-	PUNCT
dti-1352	265	26	term	term	NOUN
dti-1352	265	27	declarative	declarative	NOUN
dti-1352	265	28	memory	memory	NOUN
dti-1352	265	29	in	in	ADP
dti-1352	265	30	humans	human	NOUN
dti-1352	265	31	.	.	PUNCT
dti-1352	266	1	nat	nat	PROPN
dti-1352	266	2	neurosci	neurosci	PROPN
dti-1352	266	3	.	.	PUNCT
dti-1352	267	1	2000;3:313–4	2000;3:313–4	NUM
dti-1352	267	2	.	.	PUNCT
dti-1352	268	1	4	4	X
dti-1352	268	2	.	.	X
dti-1352	268	3	hirschfeld	hirschfeld	PROPN
dti-1352	268	4	rm	rm	PROPN
dti-1352	268	5	.	.	PUNCT
dti-1352	269	1	history	history	NOUN
dti-1352	269	2	and	and	CCONJ
dti-1352	269	3	evolution	evolution	NOUN
dti-1352	269	4	of	of	ADP
dti-1352	269	5	the	the	DET
dti-1352	269	6	monoamine	monoamine	ADJ
dti-1352	269	7	hypothesis	hypothesis	NOUN
dti-1352	269	8	of	of	ADP
dti-1352	269	9	depression	depression	NOUN
dti-1352	269	10	.	.	PUNCT
dti-1352	270	1	j	j	PROPN
dti-1352	270	2	clin	clin	PROPN
dti-1352	270	3	psychiatry	psychiatry	PROPN
dti-1352	270	4	.	.	PUNCT
dti-1352	271	1	2000;61(6):4–6	2000;61(6):4–6	NOUN
dti-1352	271	2	.	.	PUNCT
dti-1352	272	1	5	5	NUM
dti-1352	272	2	.	.	X
dti-1352	273	1	castren	castren	PROPN
dti-1352	273	2	e.	e.	PROPN
dti-1352	273	3	is	be	AUX
dti-1352	273	4	mood	mood	NOUN
dti-1352	273	5	chemistry	chemistry	NOUN
dti-1352	273	6	?	?	PUNCT
dti-1352	274	1	nat	nat	PROPN
dti-1352	274	2	rev	rev	PROPN
dti-1352	274	3	neurosci	neurosci	PROPN
dti-1352	274	4	.	.	PUNCT
dti-1352	275	1	2005;6:241–6	2005;6:241–6	NOUN
dti-1352	275	2	.	.	PUNCT
dti-1352	276	1	6	6	X
dti-1352	276	2	.	.	X
dti-1352	276	3	audinot	audinot	PROPN
dti-1352	276	4	v	v	PROPN
dti-1352	276	5	,	,	PUNCT
dti-1352	276	6	mailliet	mailliet	PROPN
dti-1352	276	7	f	f	PROPN
dti-1352	276	8	,	,	PUNCT
dti-1352	276	9	lahaye	lahaye	NOUN
dti-1352	276	10	-	-	PUNCT
dti-1352	276	11	brasseur	brasseur	NOUN
dti-1352	276	12	c	c	NOUN
dti-1352	276	13	,	,	PUNCT
dti-1352	276	14	et	et	PROPN
dti-1352	276	15	al	al	PROPN
dti-1352	276	16	.	.	PUNCT
dti-1352	277	1	new	new	ADJ
dti-1352	277	2	selective	selective	ADJ
dti-1352	277	3	ligands	ligand	NOUN
dti-1352	277	4	of	of	ADP
dti-1352	277	5	human	human	ADJ
dti-1352	277	6	cloned	clone	VERB
dti-1352	277	7	melatonin	melatonin	PROPN
dti-1352	277	8	mt1	mt1	PROPN
dti-1352	277	9	and	and	CCONJ
dti-1352	278	1	mt2	mt2	ADJ
dti-1352	278	2	receptors	receptor	NOUN
dti-1352	278	3	.	.	PUNCT
dti-1352	279	1	naunyn	naunyn	PROPN
dti-1352	279	2	schmiedebergs	schmiedebergs	PROPN
dti-1352	279	3	arch	arch	NOUN
dti-1352	279	4	pharmacol	pharmacol	NOUN
dti-1352	279	5	.	.	PUNCT
dti-1352	280	1	2003;367:553–61	2003;367:553–61	NUM
dti-1352	280	2	.	.	NOUN
dti-1352	280	3	7	7	X
dti-1352	280	4	.	.	X
dti-1352	280	5	millan	millan	PROPN
dti-1352	280	6	mj	mj	PROPN
dti-1352	280	7	,	,	PUNCT
dti-1352	280	8	gobert	gobert	VERB
dti-1352	280	9	a	a	PRON
dti-1352	280	10	,	,	PUNCT
dti-1352	280	11	lejeune	lejeune	PROPN
dti-1352	280	12	f	f	PROPN
dti-1352	280	13	,	,	PUNCT
dti-1352	280	14	et	et	PROPN
dti-1352	280	15	al	al	PROPN
dti-1352	280	16	.	.	PUNCT
dti-1352	281	1	the	the	DET
dti-1352	281	2	novel	novel	ADJ
dti-1352	281	3	melatonin	melatonin	NOUN
dti-1352	281	4	agonist	agonist	NOUN
dti-1352	281	5	agomelatine	agomelatine	NOUN
dti-1352	281	6	(	(	PUNCT
dti-1352	281	7	s20098	s20098	NOUN
dti-1352	281	8	)	)	PUNCT
dti-1352	281	9	is	be	AUX
dti-1352	281	10	an	an	DET
dti-1352	281	11	antagonist	antagonist	NOUN
dti-1352	281	12	at	at	ADP
dti-1352	281	13	5	5	NUM
dti-1352	281	14	-	-	PUNCT
dti-1352	281	15	hydroxytryptamine2c	hydroxytryptamine2c	PROPN
dti-1352	281	16	receptors	receptor	NOUN
dti-1352	281	17	,	,	PUNCT
dti-1352	281	18	blockade	blockade	NOUN
dti-1352	281	19	of	of	ADP
dti-1352	281	20	which	which	PRON
dti-1352	281	21	enhances	enhance	VERB
dti-1352	281	22	the	the	DET
dti-1352	281	23	activity	activity	NOUN
dti-1352	281	24	of	of	ADP
dti-1352	281	25	frontocortical	frontocortical	ADJ
dti-1352	281	26	dopaminergic	dopaminergic	ADJ
dti-1352	281	27	and	and	CCONJ
dti-1352	281	28	adrenergic	adrenergic	ADJ
dti-1352	281	29	pathways	pathway	NOUN
dti-1352	281	30	.	.	PUNCT
dti-1352	282	1	j	j	PROPN
dti-1352	282	2	pharmacol	pharmacol	PROPN
dti-1352	282	3	exp	exp	NOUN
dti-1352	282	4	ther	ther	ADV
dti-1352	282	5	.	.	PUNCT
dti-1352	283	1	2003;306:954–64	2003;306:954–64	NUM
dti-1352	283	2	.	.	NOUN
dti-1352	283	3	8	8	NUM
dti-1352	283	4	.	.	PUNCT
dti-1352	284	1	pitrosky	pitrosky	PROPN
dti-1352	284	2	b	b	PROPN
dti-1352	284	3	,	,	PUNCT
dti-1352	284	4	kirsch	kirsch	PROPN
dti-1352	284	5	r	r	PROPN
dti-1352	284	6	,	,	PUNCT
dti-1352	284	7	malan	malan	PROPN
dti-1352	284	8	a	a	PROPN
dti-1352	284	9	,	,	PUNCT
dti-1352	284	10	mocaer	mocaer	PROPN
dti-1352	284	11	e	e	NOUN
dti-1352	284	12	,	,	PUNCT
dti-1352	284	13	pevet	pevet	ADJ
dti-1352	284	14	p.	p.	NOUN
dti-1352	284	15	organization	organization	NOUN
dti-1352	284	16	of	of	ADP
dti-1352	284	17	rat	rat	NOUN
dti-1352	284	18	circadian	circadian	ADJ
dti-1352	284	19	rhythms	rhythm	NOUN
dti-1352	284	20	during	during	ADP
dti-1352	284	21	daily	daily	ADJ
dti-1352	284	22	infusion	infusion	NOUN
dti-1352	284	23	of	of	ADP
dti-1352	284	24	melatonin	melatonin	NOUN
dti-1352	284	25	or	or	CCONJ
dti-1352	284	26	s20098	s20098	NOUN
dti-1352	284	27	,	,	PUNCT
dti-1352	284	28	a	a	DET
dti-1352	284	29	melatonin	melatonin	NOUN
dti-1352	284	30	agonist	agonist	NOUN
dti-1352	284	31	.	.	PUNCT
dti-1352	285	1	am	be	AUX
dti-1352	285	2	j	j	PROPN
dti-1352	285	3	phys	phy	NOUN
dti-1352	285	4	.	.	PUNCT
dti-1352	286	1	1999;277:812–28	1999;277:812–28	NUM
dti-1352	286	2	.	.	PUNCT
dti-1352	287	1	9	9	X
dti-1352	287	2	.	.	X
dti-1352	287	3	bertaina	bertaina	PROPN
dti-1352	287	4	-	-	PUNCT
dti-1352	287	5	anglade	anglade	NOUN
dti-1352	287	6	v	v	NOUN
dti-1352	287	7	,	,	PUNCT
dti-1352	287	8	la	la	DET
dti-1352	287	9	rochelle	rochelle	PROPN
dti-1352	287	10	cd	cd	PROPN
dti-1352	287	11	,	,	PUNCT
dti-1352	287	12	boyer	boyer	PROPN
dti-1352	287	13	pa	pa	PROPN
dti-1352	287	14	,	,	PUNCT
dti-1352	287	15	mocaer	mocaer	PROPN
dti-1352	287	16	e.	e.	PROPN
dti-1352	287	17	antidepressant	antidepressant	PROPN
dti-1352	287	18	-	-	PUNCT
dti-1352	287	19	like	like	ADJ
dti-1352	287	20	effects	effect	NOUN
dti-1352	287	21	of	of	ADP
dti-1352	287	22	agomelatine	agomelatine	NOUN
dti-1352	287	23	(	(	PUNCT
dti-1352	287	24	s	s	NOUN
dti-1352	287	25	20098	20098	NUM
dti-1352	287	26	)	)	PUNCT
dti-1352	287	27	in	in	ADP
dti-1352	287	28	the	the	DET
dti-1352	287	29	learned	learn	VERB
dti-1352	287	30	helplessness	helplessness	NOUN
dti-1352	287	31	model	model	NOUN
dti-1352	287	32	.	.	PUNCT
dti-1352	288	1	behav	behav	PROPN
dti-1352	288	2	pharmacol	pharmacol	PROPN
dti-1352	288	3	.	.	PUNCT
dti-1352	289	1	2006;17:703–13	2006;17:703–13	NUM
dti-1352	289	2	.	.	NOUN
dti-1352	289	3	10	10	NUM
dti-1352	289	4	.	.	PUNCT
dti-1352	290	1	barden	barden	PROPN
dti-1352	290	2	n	n	CCONJ
dti-1352	290	3	,	,	PUNCT
dti-1352	290	4	shink	shink	VERB
dti-1352	290	5	e	e	NOUN
dti-1352	290	6	,	,	PUNCT
dti-1352	290	7	labbe	labbe	PROPN
dti-1352	290	8	m	m	PROPN
dti-1352	290	9	,	,	PUNCT
dti-1352	290	10	vacher	vacher	NOUN
dti-1352	290	11	r	r	NOUN
dti-1352	290	12	,	,	PUNCT
dti-1352	290	13	rochford	rochford	PROPN
dti-1352	290	14	j	j	PROPN
dti-1352	290	15	,	,	PUNCT
dti-1352	290	16	mocaer	mocaer	PROPN
dti-1352	290	17	e.	e.	PROPN
dti-1352	290	18	antidepressant	antidepressant	PROPN
dti-1352	290	19	action	action	NOUN
dti-1352	290	20	of	of	ADP
dti-1352	290	21	agomelatine	agomelatine	NOUN
dti-1352	290	22	(	(	PUNCT
dti-1352	290	23	s	s	NOUN
dti-1352	290	24	20098	20098	NUM
dti-1352	290	25	)	)	PUNCT
dti-1352	290	26	in	in	ADP
dti-1352	290	27	a	a	DET
dti-1352	290	28	transgenic	transgenic	NOUN
dti-1352	290	29	mouse	mouse	NOUN
dti-1352	290	30	model	model	NOUN
dti-1352	290	31	.	.	PUNCT
dti-1352	291	1	prog	prog	PROPN
dti-1352	291	2	neuropsychopharmacol	neuropsychopharmacol	PROPN
dti-1352	291	3	biol	biol	PROPN
dti-1352	291	4	psychiatry	psychiatry	NOUN
dti-1352	291	5	.	.	PUNCT
dti-1352	292	1	2005;29:908–16	2005;29:908–16	X
dti-1352	292	2	.	.	PROPN
dti-1352	293	1	11	11	NUM
dti-1352	293	2	.	.	PUNCT
dti-1352	294	1	kennedy	kennedy	PROPN
dti-1352	294	2	sh	sh	PROPN
dti-1352	294	3	,	,	PUNCT
dti-1352	294	4	emsley	emsley	PROPN
dti-1352	294	5	r.	r.	PROPN
dti-1352	294	6	placebo	placebo	PROPN
dti-1352	294	7	-	-	PUNCT
dti-1352	294	8	controlled	control	VERB
dti-1352	294	9	trial	trial	NOUN
dti-1352	294	10	of	of	ADP
dti-1352	294	11	agomelatine	agomelatine	NOUN
dti-1352	294	12	in	in	ADP
dti-1352	294	13	the	the	DET
dti-1352	294	14	treatment	treatment	NOUN
dti-1352	294	15	of	of	ADP
dti-1352	294	16	major	major	ADJ
dti-1352	294	17	depressive	depressive	ADJ
dti-1352	294	18	disorder	disorder	NOUN
dti-1352	294	19	.	.	PUNCT
dti-1352	295	1	eur	eur	PROPN
dti-1352	295	2	neuropsychopharm	neuropsychopharm	NOUN
dti-1352	295	3	.	.	PUNCT
dti-1352	296	1	2006;16:93–100	2006;16:93–100	X
dti-1352	296	2	.	.	PUNCT
dti-1352	297	1	12	12	NUM
dti-1352	297	2	.	.	PUNCT
dti-1352	297	3	quera	quera	PROPN
dti-1352	297	4	salva	salva	PROPN
dti-1352	297	5	ma	ma	PROPN
dti-1352	297	6	,	,	PUNCT
dti-1352	297	7	vanier	vanier	PROPN
dti-1352	297	8	b	b	PROPN
dti-1352	297	9	,	,	PUNCT
dti-1352	297	10	laredo	laredo	PROPN
dti-1352	297	11	j	j	PROPN
dti-1352	297	12	,	,	PUNCT
dti-1352	297	13	et	et	PROPN
dti-1352	297	14	al	al	PROPN
dti-1352	297	15	.	.	PUNCT
dti-1352	298	1	major	major	ADJ
dti-1352	298	2	depressive	depressive	ADJ
dti-1352	298	3	disorder	disorder	NOUN
dti-1352	298	4	,	,	PUNCT
dti-1352	298	5	sleep	sleep	NOUN
dti-1352	298	6	eeg	eeg	X
dti-1352	298	7	and	and	CCONJ
dti-1352	298	8	agomelatine	agomelatine	PROPN
dti-1352	298	9	:	:	PUNCT
dti-1352	298	10	an	an	DET
dti-1352	298	11	open	open	ADJ
dti-1352	298	12	label	label	NOUN
dti-1352	298	13	study	study	NOUN
dti-1352	298	14	.	.	PUNCT
dti-1352	299	1	int	int	PROPN
dti-1352	300	1	j	j	PROPN
dti-1352	300	2	neuropsychopharmacol	neuropsychopharmacol	NOUN
dti-1352	300	3	.	.	PUNCT
dti-1352	301	1	2007;10:691–6	2007;10:691–6	NUM
dti-1352	301	2	.	.	PUNCT
dti-1352	302	1	13	13	NUM
dti-1352	302	2	.	.	PUNCT
dti-1352	303	1	mcclung	mcclung	PROPN
dti-1352	303	2	ca	ca	PROPN
dti-1352	303	3	.	.	PUNCT
dti-1352	304	1	circadian	circadian	ADJ
dti-1352	304	2	genes	gene	NOUN
dti-1352	304	3	,	,	PUNCT
dti-1352	304	4	rhythms	rhythm	NOUN
dti-1352	304	5	and	and	CCONJ
dti-1352	304	6	the	the	DET
dti-1352	304	7	biology	biology	NOUN
dti-1352	304	8	of	of	ADP
dti-1352	304	9	mood	mood	NOUN
dti-1352	304	10	disorders	disorder	NOUN
dti-1352	304	11	.	.	PUNCT
dti-1352	305	1	pharmacol	pharmacol	VERB
dti-1352	305	2	ther	ther	ADV
dti-1352	305	3	.	.	PUNCT
dti-1352	306	1	2007;114:222–32	2007;114:222–32	X
dti-1352	306	2	.	.	PUNCT
dti-1352	307	1	14	14	NUM
dti-1352	307	2	.	.	PUNCT
dti-1352	308	1	willner	willn	ADJ
dti-1352	308	2	p.	p.	PROPN
dti-1352	308	3	validity	validity	NOUN
dti-1352	308	4	,	,	PUNCT
dti-1352	308	5	reliability	reliability	NOUN
dti-1352	308	6	and	and	CCONJ
dti-1352	308	7	utility	utility	NOUN
dti-1352	308	8	of	of	ADP
dti-1352	308	9	the	the	DET
dti-1352	308	10	chronic	chronic	ADJ
dti-1352	308	11	mild	mild	ADJ
dti-1352	308	12	stress	stress	NOUN
dti-1352	308	13	model	model	NOUN
dti-1352	308	14	of	of	ADP
dti-1352	308	15	depression	depression	NOUN
dti-1352	308	16	:	:	PUNCT
dti-1352	308	17	a	a	DET
dti-1352	308	18	10	10	NUM
dti-1352	308	19	years	year	NOUN
dti-1352	308	20	review	review	NOUN
dti-1352	308	21	and	and	CCONJ
dti-1352	308	22	evaluation	evaluation	NOUN
dti-1352	308	23	.	.	PUNCT
dti-1352	309	1	psychopharmacology	psychopharmacology	NOUN
dti-1352	309	2	.	.	PUNCT
dti-1352	310	1	1997;134:319–29	1997;134:319–29	X
dti-1352	310	2	.	.	NOUN
dti-1352	311	1	15	15	NUM
dti-1352	311	2	.	.	PUNCT
dti-1352	312	1	gumuslu	gumuslu	PROPN
dti-1352	312	2	e	e	PROPN
dti-1352	312	3	,	,	PUNCT
dti-1352	312	4	mutlu	mutlu	PROPN
dti-1352	312	5	o	o	NOUN
dti-1352	312	6	,	,	PUNCT
dti-1352	312	7	sunnetci	sunnetci	ADP
dti-1352	312	8	d	d	PROPN
dti-1352	312	9	,	,	PUNCT
dti-1352	312	10	et	et	PROPN
dti-1352	312	11	al	al	PROPN
dti-1352	312	12	.	.	PUNCT
dti-1352	313	1	the	the	DET
dti-1352	313	2	effects	effect	NOUN
dti-1352	313	3	of	of	ADP
dti-1352	313	4	tianeptine	tianeptine	NOUN
dti-1352	313	5	,	,	PUNCT
dti-1352	313	6	olanzapine	olanzapine	NOUN
dti-1352	313	7	and	and	CCONJ
dti-1352	313	8	fluoxetine	fluoxetine	NOUN
dti-1352	313	9	on	on	ADP
dti-1352	313	10	the	the	DET
dti-1352	313	11	cognitive	cognitive	ADJ
dti-1352	313	12	behaviors	behavior	NOUN
dti-1352	313	13	of	of	ADP
dti-1352	313	14	unpredictable	unpredictable	ADJ
dti-1352	313	15	chronic	chronic	ADJ
dti-1352	313	16	mild	mild	ADJ
dti-1352	313	17	stressexposed	stressexpose	VERB
dti-1352	313	18	mice	mouse	NOUN
dti-1352	313	19	.	.	PUNCT
dti-1352	314	1	drug	drug	NOUN
dti-1352	314	2	res	re	NOUN
dti-1352	314	3	.	.	PUNCT
dti-1352	315	1	2013;63:532–9	2013;63:532–9	NUM
dti-1352	315	2	.	.	PROPN
dti-1352	315	3	16	16	NUM
dti-1352	315	4	.	.	PUNCT
dti-1352	316	1	tardito	tardito	PROPN
dti-1352	316	2	d	d	PROPN
dti-1352	316	3	,	,	PUNCT
dti-1352	316	4	perez	perez	PROPN
dti-1352	316	5	j	j	PROPN
dti-1352	316	6	,	,	PUNCT
dti-1352	316	7	tiraboschi	tiraboschi	PROPN
dti-1352	316	8	e	e	NOUN
dti-1352	316	9	,	,	PUNCT
dti-1352	316	10	musazzi	musazzi	PROPN
dti-1352	316	11	l	l	NOUN
dti-1352	316	12	,	,	PUNCT
dti-1352	316	13	racagni	racagni	NOUN
dti-1352	316	14	g	g	NOUN
dti-1352	316	15	,	,	PUNCT
dti-1352	316	16	popoli	popoli	NOUN
dti-1352	316	17	m.	m.	NOUN
dti-1352	316	18	signaling	signal	VERB
dti-1352	316	19	pathways	pathway	NOUN
dti-1352	316	20	regulating	regulate	VERB
dti-1352	316	21	gene	gene	NOUN
dti-1352	316	22	expression	expression	NOUN
dti-1352	316	23	,	,	PUNCT
dti-1352	316	24	neuroplasticity	neuroplasticity	NOUN
dti-1352	316	25	,	,	PUNCT
dti-1352	316	26	and	and	CCONJ
dti-1352	316	27	neurotrophic	neurotrophic	ADJ
dti-1352	316	28	mechanisms	mechanism	NOUN
dti-1352	316	29	in	in	ADP
dti-1352	316	30	the	the	DET
dti-1352	316	31	action	action	NOUN
dti-1352	316	32	of	of	ADP
dti-1352	316	33	antidepressants	antidepressant	NOUN
dti-1352	316	34	:	:	PUNCT
dti-1352	316	35	a	a	DET
dti-1352	316	36	critical	critical	ADJ
dti-1352	316	37	overview	overview	NOUN
dti-1352	316	38	.	.	PUNCT
dti-1352	317	1	pharmacol	pharmacol	PROPN
dti-1352	317	2	rev	rev	PROPN
dti-1352	317	3	.	.	PUNCT
dti-1352	318	1	2006;58:115–34	2006;58:115–34	NUM
dti-1352	318	2	.	.	PROPN
dti-1352	318	3	17	17	NUM
dti-1352	318	4	.	.	PUNCT
dti-1352	318	5	bramham	bramham	PROPN
dti-1352	318	6	cr	cr	PROPN
dti-1352	318	7	,	,	PUNCT
dti-1352	318	8	messaoudi	messaoudi	PROPN
dti-1352	318	9	e.	e.	PROPN
dti-1352	318	10	bdnf	bdnf	PROPN
dti-1352	318	11	function	function	PROPN
dti-1352	318	12	in	in	ADP
dti-1352	318	13	adult	adult	NOUN
dti-1352	318	14	synaptic	synaptic	ADJ
dti-1352	318	15	plasticity	plasticity	NOUN
dti-1352	318	16	:	:	PUNCT
dti-1352	318	17	the	the	DET
dti-1352	318	18	synaptic	synaptic	ADJ
dti-1352	318	19	consolidation	consolidation	NOUN
dti-1352	318	20	hypothesis	hypothesis	NOUN
dti-1352	318	21	.	.	PUNCT
dti-1352	319	1	prog	prog	PROPN
dti-1352	319	2	neurobiol	neurobiol	PROPN
dti-1352	319	3	.	.	PUNCT
dti-1352	320	1	2005;76:99–125	2005;76:99–125	NUM
dti-1352	320	2	.	.	PUNCT
dti-1352	321	1	18	18	NUM
dti-1352	321	2	.	.	X
dti-1352	321	3	cirelli	cirelli	PROPN
dti-1352	321	4	c	c	PROPN
dti-1352	321	5	,	,	PUNCT
dti-1352	321	6	tononi	tononi	NOUN
dti-1352	321	7	g.	g.	NOUN
dti-1352	321	8	differential	differential	NOUN
dti-1352	321	9	expression	expression	NOUN
dti-1352	321	10	of	of	ADP
dti-1352	321	11	plasticity	plasticity	NOUN
dti-1352	321	12	related	relate	VERB
dti-1352	321	13	genes	gene	NOUN
dti-1352	321	14	in	in	ADP
dti-1352	321	15	waking	wake	VERB
dti-1352	321	16	and	and	CCONJ
dti-1352	321	17	sleep	sleep	NOUN
dti-1352	321	18	and	and	CCONJ
dti-1352	321	19	their	their	PRON
dti-1352	321	20	regulation	regulation	NOUN
dti-1352	321	21	by	by	ADP
dti-1352	321	22	the	the	DET
dti-1352	321	23	noradrenergic	noradrenergic	ADJ
dti-1352	321	24	system	system	NOUN
dti-1352	321	25	.	.	PUNCT
dti-1352	322	1	j	j	PROPN
dti-1352	322	2	neurosci	neurosci	PROPN
dti-1352	322	3	.	.	PUNCT
dti-1352	323	1	2000;20:9187–94	2000;20:9187–94	NUM
dti-1352	323	2	.	.	X
dti-1352	324	1	19	19	NUM
dti-1352	324	2	.	.	X
dti-1352	324	3	begliuomini	begliuomini	PROPN
dti-1352	324	4	s	s	PROPN
dti-1352	324	5	,	,	PUNCT
dti-1352	324	6	lenzi	lenzi	PROPN
dti-1352	324	7	e	e	PROPN
dti-1352	324	8	,	,	PUNCT
dti-1352	324	9	ninni	ninni	PROPN
dti-1352	324	10	f	f	PROPN
dti-1352	324	11	,	,	PUNCT
dti-1352	324	12	et	et	PROPN
dti-1352	324	13	al	al	PROPN
dti-1352	324	14	.	.	PUNCT
dti-1352	324	15	plasma	plasma	NOUN
dti-1352	324	16	brain	brain	NOUN
dti-1352	324	17	-	-	PUNCT
dti-1352	324	18	derived	derive	VERB
dti-1352	324	19	neurotrophic	neurotrophic	ADJ
dti-1352	324	20	factor	factor	NOUN
dti-1352	324	21	daily	daily	ADJ
dti-1352	324	22	variations	variation	NOUN
dti-1352	324	23	in	in	ADP
dti-1352	324	24	men	man	NOUN
dti-1352	324	25	:	:	PUNCT
dti-1352	324	26	correlation	correlation	NOUN
dti-1352	324	27	with	with	ADP
dti-1352	324	28	cortisol	cortisol	ADJ
dti-1352	324	29	circadian	circadian	ADJ
dti-1352	324	30	rhythm	rhythm	NOUN
dti-1352	324	31	.	.	PUNCT
dti-1352	325	1	j	j	PROPN
dti-1352	325	2	endocrinol	endocrinol	NOUN
dti-1352	325	3	.	.	PUNCT
dti-1352	326	1	2008;197:429–35	2008;197:429–35	NUM
dti-1352	326	2	.	.	NOUN
dti-1352	326	3	20	20	NUM
dti-1352	326	4	.	.	PUNCT
dti-1352	327	1	calabrese	calabrese	PROPN
dti-1352	327	2	f	f	PROPN
dti-1352	327	3	,	,	PUNCT
dti-1352	327	4	molteni	molteni	PROPN
dti-1352	327	5	r	r	NOUN
dti-1352	327	6	,	,	PUNCT
dti-1352	327	7	racagni	racagni	NOUN
dti-1352	327	8	g	g	NOUN
dti-1352	327	9	,	,	PUNCT
dti-1352	327	10	riva	riva	PROPN
dti-1352	327	11	ma	ma	PROPN
dti-1352	327	12	.	.	PROPN
dti-1352	327	13	neuronal	neuronal	ADJ
dti-1352	327	14	plasticity	plasticity	NOUN
dti-1352	327	15	:	:	PUNCT
dti-1352	327	16	a	a	DET
dti-1352	327	17	link	link	NOUN
dti-1352	327	18	between	between	ADP
dti-1352	327	19	stress	stress	NOUN
dti-1352	327	20	and	and	CCONJ
dti-1352	327	21	mood	mood	NOUN
dti-1352	327	22	disorders	disorder	NOUN
dti-1352	327	23	.	.	PUNCT
dti-1352	328	1	psychoneuroendocrinology	psychoneuroendocrinology	NOUN
dti-1352	328	2	.	.	PUNCT
dti-1352	329	1	2009;34(1):208–16	2009;34(1):208–16	X
dti-1352	329	2	.	.	NOUN
dti-1352	329	3	21	21	NUM
dti-1352	329	4	.	.	PUNCT
dti-1352	329	5	porsolt	porsolt	PROPN
dti-1352	329	6	rd	rd	PROPN
dti-1352	329	7	,	,	PUNCT
dti-1352	329	8	le	le	PROPN
dti-1352	329	9	pichon	pichon	PROPN
dti-1352	329	10	m	m	PROPN
dti-1352	329	11	,	,	PUNCT
dti-1352	329	12	jalfre	jalfre	PROPN
dti-1352	329	13	m.	m.	NOUN
dti-1352	329	14	depression	depression	NOUN
dti-1352	329	15	:	:	PUNCT
dti-1352	329	16	a	a	DET
dti-1352	329	17	new	new	ADJ
dti-1352	329	18	animal	animal	NOUN
dti-1352	329	19	model	model	NOUN
dti-1352	329	20	sensitive	sensitive	ADJ
dti-1352	329	21	to	to	ADP
dti-1352	329	22	antidepressant	antidepressant	ADJ
dti-1352	329	23	treatments	treatment	NOUN
dti-1352	329	24	.	.	PUNCT
dti-1352	330	1	nature	nature	NOUN
dti-1352	330	2	.	.	PUNCT
dti-1352	331	1	1977;266:730–2	1977;266:730–2	X
dti-1352	331	2	.	.	PUNCT
dti-1352	332	1	22	22	NUM
dti-1352	332	2	.	.	PUNCT
dti-1352	332	3	ennaceur	ennaceur	PROPN
dti-1352	332	4	a	a	NOUN
dti-1352	332	5	,	,	PUNCT
dti-1352	332	6	delacour	delacour	PROPN
dti-1352	332	7	j.	j.	PROPN
dti-1352	332	8	a	a	DET
dti-1352	332	9	new	new	ADJ
dti-1352	332	10	one	one	NUM
dti-1352	332	11	-	-	PUNCT
dti-1352	332	12	trial	trial	NOUN
dti-1352	332	13	test	test	NOUN
dti-1352	332	14	for	for	ADP
dti-1352	332	15	neurobiological	neurobiological	ADJ
dti-1352	332	16	studies	study	NOUN
dti-1352	332	17	of	of	ADP
dti-1352	332	18	memory	memory	NOUN
dti-1352	332	19	in	in	ADP
dti-1352	332	20	rats	rat	NOUN
dti-1352	332	21	.	.	PUNCT
dti-1352	333	1	1	1	NUM
dti-1352	333	2	behavioral	behavioral	ADJ
dti-1352	333	3	data	datum	NOUN
dti-1352	333	4	.	.	PUNCT
dti-1352	334	1	behav	behav	NOUN
dti-1352	334	2	brain	brain	NOUN
dti-1352	334	3	res	re	NOUN
dti-1352	334	4	.	.	PUNCT
dti-1352	335	1	1988;31:47–59	1988;31:47–59	NUM
dti-1352	335	2	.	.	PROPN
dti-1352	335	3	23	23	NUM
dti-1352	335	4	.	.	PUNCT
dti-1352	336	1	barco	barco	PROPN
dti-1352	336	2	a	a	PROPN
dti-1352	336	3	,	,	PUNCT
dti-1352	336	4	pittenger	pittenger	NOUN
dti-1352	336	5	c	c	NOUN
dti-1352	336	6	,	,	PUNCT
dti-1352	336	7	kandel	kandel	PROPN
dti-1352	336	8	er	er	INTJ
dti-1352	336	9	.	.	PUNCT
dti-1352	336	10	creb	creb	PROPN
dti-1352	336	11	,	,	PUNCT
dti-1352	336	12	memory	memory	NOUN
dti-1352	336	13	enhancement	enhancement	NOUN
dti-1352	336	14	and	and	CCONJ
dti-1352	336	15	the	the	DET
dti-1352	336	16	treatment	treatment	NOUN
dti-1352	336	17	of	of	ADP
dti-1352	336	18	memory	memory	NOUN
dti-1352	336	19	disorders	disorder	NOUN
dti-1352	336	20	:	:	PUNCT
dti-1352	336	21	promises	promise	NOUN
dti-1352	336	22	,	,	PUNCT
dti-1352	336	23	pitfalls	pitfall	NOUN
dti-1352	336	24	and	and	CCONJ
dti-1352	336	25	prospects	prospect	NOUN
dti-1352	336	26	.	.	PUNCT
dti-1352	337	1	expert	expert	NOUN
dti-1352	337	2	opin	opin	NOUN
dti-1352	337	3	ther	ther	ADJ
dti-1352	337	4	targets	target	NOUN
dti-1352	337	5	.	.	PUNCT
dti-1352	338	1	2013;7(1):101–14	2013;7(1):101–14	NUM
dti-1352	338	2	.	.	PUNCT
dti-1352	338	3	24	24	NUM
dti-1352	338	4	.	.	PUNCT
dti-1352	338	5	muscat	muscat	PROPN
dti-1352	338	6	r	r	NOUN
dti-1352	338	7	,	,	PUNCT
dti-1352	338	8	willner	willn	ADJ
dti-1352	338	9	p.	p.	NOUN
dti-1352	338	10	suppression	suppression	NOUN
dti-1352	338	11	of	of	ADP
dti-1352	338	12	sucrose	sucrose	NOUN
dti-1352	338	13	drinking	drinking	NOUN
dti-1352	338	14	by	by	ADP
dti-1352	338	15	chronic	chronic	ADJ
dti-1352	338	16	mild	mild	ADJ
dti-1352	338	17	unpredictable	unpredictable	ADJ
dti-1352	338	18	stress	stress	NOUN
dti-1352	338	19	:	:	PUNCT
dti-1352	338	20	a	a	DET
dti-1352	338	21	methodological	methodological	ADJ
dti-1352	338	22	analysis	analysis	NOUN
dti-1352	338	23	.	.	PUNCT
dti-1352	339	1	neurosci	neurosci	PROPN
dti-1352	339	2	biobehav	biobehav	PROPN
dti-1352	339	3	rev	rev	VERB
dti-1352	339	4	.	.	PUNCT
dti-1352	340	1	1992;16:507–17	1992;16:507–17	NUM
dti-1352	340	2	.	.	PUNCT
dti-1352	341	1	25	25	NUM
dti-1352	341	2	.	.	X
dti-1352	341	3	arbe	arbe	PROPN
dti-1352	341	4	md	md	PROPN
dti-1352	341	5	,	,	PUNCT
dti-1352	341	6	einstein	einstein	PROPN
dti-1352	341	7	r	r	PROPN
dti-1352	341	8	,	,	PUNCT
dti-1352	341	9	lavidis	lavidis	PROPN
dti-1352	341	10	na	na	PROPN
dti-1352	341	11	.	.	PUNCT
dti-1352	341	12	stressful	stressful	ADJ
dti-1352	341	13	animal	animal	NOUN
dti-1352	341	14	housing	housing	NOUN
dti-1352	341	15	conditions	condition	NOUN
dti-1352	341	16	and	and	CCONJ
dti-1352	341	17	their	their	PRON
dti-1352	341	18	potential	potential	ADJ
dti-1352	341	19	effect	effect	NOUN
dti-1352	341	20	on	on	ADP
dti-1352	341	21	sympathetic	sympathetic	ADJ
dti-1352	341	22	neurotransmission	neurotransmission	NOUN
dti-1352	341	23	in	in	ADP
dti-1352	341	24	mice	mouse	NOUN
dti-1352	341	25	.	.	PUNCT
dti-1352	341	26	am	be	AUX
dti-1352	341	27	j	j	PROPN
dti-1352	341	28	physiol	physiol	PROPN
dti-1352	341	29	regul	regul	PROPN
dti-1352	341	30	integr	integr	PROPN
dti-1352	341	31	comp	comp	PROPN
dti-1352	341	32	physiol	physiol	PROPN
dti-1352	341	33	.	.	PUNCT
dti-1352	342	1	2002;282:1422–8	2002;282:1422–8	NOUN
dti-1352	342	2	.	.	PUNCT
dti-1352	343	1	26	26	NUM
dti-1352	343	2	.	.	PUNCT
dti-1352	344	1	willner	willner	NOUN
dti-1352	344	2	p	p	NOUN
dti-1352	344	3	,	,	PUNCT
dti-1352	344	4	muscat	muscat	PROPN
dti-1352	344	5	r	r	NOUN
dti-1352	344	6	,	,	PUNCT
dti-1352	344	7	papp	papp	NOUN
dti-1352	344	8	m.	m.	NOUN
dti-1352	344	9	chronic	chronic	PROPN
dti-1352	344	10	mild	mild	ADJ
dti-1352	344	11	stress	stress	NOUN
dti-1352	344	12	-	-	PUNCT
dti-1352	344	13	induced	induce	VERB
dti-1352	344	14	anhedonia	anhedonia	NOUN
dti-1352	344	15	:	:	PUNCT
dti-1352	344	16	a	a	DET
dti-1352	344	17	realistic	realistic	ADJ
dti-1352	344	18	animal	animal	NOUN
dti-1352	344	19	model	model	NOUN
dti-1352	344	20	of	of	ADP
dti-1352	344	21	depression	depression	NOUN
dti-1352	344	22	.	.	PUNCT
dti-1352	345	1	neurosci	neurosci	PROPN
dti-1352	345	2	biobehav	biobehav	PROPN
dti-1352	345	3	rev	rev	VERB
dti-1352	345	4	.	.	PUNCT
dti-1352	346	1	1992;16:525–34	1992;16:525–34	NUM
dti-1352	346	2	.	.	PROPN
dti-1352	346	3	27	27	NUM
dti-1352	346	4	.	.	PUNCT
dti-1352	347	1	ducottet	ducottet	NOUN
dti-1352	347	2	c	c	PROPN
dti-1352	347	3	,	,	PUNCT
dti-1352	347	4	belzung	belzung	PROPN
dti-1352	347	5	c.	c.	PROPN
dti-1352	347	6	behaviour	behaviour	NOUN
dti-1352	347	7	in	in	ADP
dti-1352	347	8	the	the	DET
dti-1352	347	9	elevated	elevated	ADJ
dti-1352	347	10	plus	plus	ADJ
dti-1352	347	11	-	-	PUNCT
dti-1352	347	12	maze	maze	NOUN
dti-1352	347	13	predicts	predict	NOUN
dti-1352	347	14	coping	cope	VERB
dti-1352	347	15	after	after	ADP
dti-1352	347	16	subchronic	subchronic	ADJ
dti-1352	347	17	mild	mild	ADJ
dti-1352	347	18	stress	stress	NOUN
dti-1352	347	19	in	in	ADP
dti-1352	347	20	mice	mouse	NOUN
dti-1352	347	21	.	.	PUNCT
dti-1352	348	1	physiol	physiol	PROPN
dti-1352	348	2	behav	behav	PROPN
dti-1352	348	3	.	.	PUNCT
dti-1352	349	1	2004;81:417–26	2004;81:417–26	NUM
dti-1352	349	2	.	.	NOUN
dti-1352	349	3	28	28	NUM
dti-1352	349	4	.	.	PUNCT
dti-1352	350	1	yalcin	yalcin	PROPN
dti-1352	350	2	i	i	PRON
dti-1352	350	3	,	,	PUNCT
dti-1352	350	4	aksu	aksu	PROPN
dti-1352	350	5	f	f	PROPN
dti-1352	350	6	,	,	PUNCT
dti-1352	350	7	belzung	belzung	PROPN
dti-1352	350	8	c.	c.	PROPN
dti-1352	350	9	effects	effect	NOUN
dti-1352	350	10	of	of	ADP
dti-1352	350	11	desipramine	desipramine	NOUN
dti-1352	350	12	and	and	CCONJ
dti-1352	350	13	tramadol	tramadol	NOUN
dti-1352	350	14	in	in	ADP
dti-1352	350	15	a	a	DET
dti-1352	350	16	chronic	chronic	ADJ
dti-1352	350	17	mild	mild	ADJ
dti-1352	350	18	stress	stress	NOUN
dti-1352	350	19	model	model	NOUN
dti-1352	350	20	in	in	ADP
dti-1352	350	21	mice	mouse	NOUN
dti-1352	350	22	are	be	AUX
dti-1352	350	23	altered	alter	VERB
dti-1352	350	24	by	by	ADP
dti-1352	350	25	yohimbine	yohimbine	NOUN
dti-1352	350	26	but	but	CCONJ
dti-1352	350	27	not	not	PART
dti-1352	350	28	by	by	ADP
dti-1352	350	29	pindolol	pindolol	NOUN
dti-1352	350	30	.	.	PUNCT
dti-1352	351	1	eur	eur	PROPN
dti-1352	351	2	j	j	PROPN
dti-1352	351	3	pharmacol	pharmacol	PROPN
dti-1352	351	4	.	.	PUNCT
dti-1352	352	1	2005;514:165–74	2005;514:165–74	NUM
dti-1352	352	2	.	.	NOUN
dti-1352	352	3	29	29	NUM
dti-1352	352	4	.	.	PUNCT
dti-1352	353	1	ogren	ogren	NOUN
dti-1352	353	2	so	so	ADV
dti-1352	353	3	,	,	PUNCT
dti-1352	353	4	johansson	johansson	PROPN
dti-1352	353	5	c	c	PROPN
dti-1352	353	6	,	,	PUNCT
dti-1352	353	7	magnusson	magnusson	PROPN
dti-1352	353	8	o.	o.	NOUN
dti-1352	353	9	forebrain	forebrain	NOUN
dti-1352	353	10	serotonergic	serotonergic	ADJ
dti-1352	353	11	involvement	involvement	NOUN
dti-1352	353	12	in	in	ADP
dti-1352	353	13	avoidance	avoidance	NOUN
dti-1352	353	14	learning	learning	NOUN
dti-1352	353	15	,	,	PUNCT
dti-1352	353	16	neurosci	neurosci	PROPN
dti-1352	353	17	lett	lett	PROPN
dti-1352	353	18	.	.	PUNCT
dti-1352	354	1	1985;58:305–9	1985;58:305–9	NUM
dti-1352	354	2	.	.	PUNCT
dti-1352	355	1	30	30	NUM
dti-1352	355	2	.	.	PUNCT
dti-1352	356	1	reddy	reddy	PROPN
dti-1352	356	2	ds	ds	PROPN
dti-1352	356	3	,	,	PUNCT
dti-1352	356	4	kulkarni	kulkarni	PROPN
dti-1352	356	5	sk	sk	PROPN
dti-1352	356	6	.	.	PROPN
dti-1352	356	7	possible	possible	ADJ
dti-1352	356	8	role	role	NOUN
dti-1352	356	9	of	of	ADP
dti-1352	356	10	nitric	nitric	ADJ
dti-1352	356	11	oxide	oxide	NOUN
dti-1352	356	12	in	in	ADP
dti-1352	356	13	the	the	DET
dti-1352	356	14	nootropic	nootropic	NOUN
dti-1352	356	15	and	and	CCONJ
dti-1352	356	16	antiamnesic	antiamnesic	ADJ
dti-1352	356	17	effects	effect	NOUN
dti-1352	356	18	of	of	ADP
dti-1352	356	19	neurosteroids	neurosteroid	NOUN
dti-1352	356	20	on	on	ADP
dti-1352	356	21	agingand	agingand	NOUN
dti-1352	356	22	dizocilpine	dizocilpine	NOUN
dti-1352	356	23	-	-	PUNCT
dti-1352	356	24	induced	induce	VERB
dti-1352	356	25	learning	learning	NOUN
dti-1352	356	26	impairment	impairment	NOUN
dti-1352	356	27	.	.	PUNCT
dti-1352	357	1	brain	brain	NOUN
dti-1352	357	2	res	re	NOUN
dti-1352	357	3	.	.	PUNCT
dti-1352	358	1	1998;799:215–29	1998;799:215–29	PROPN
dti-1352	358	2	.	.	PROPN
dti-1352	359	1	31	31	NUM
dti-1352	359	2	.	.	PUNCT
dti-1352	360	1	hlinak	hlinak	PROPN
dti-1352	360	2	z	z	PROPN
dti-1352	360	3	,	,	PUNCT
dti-1352	360	4	krejci	krejci	PROPN
dti-1352	360	5	i.	i.	PROPN
dti-1352	360	6	concurrent	concurrent	PROPN
dti-1352	360	7	administration	administration	PROPN
dti-1352	360	8	of	of	ADP
dti-1352	360	9	subeffective	subeffective	ADJ
dti-1352	360	10	doses	dose	NOUN
dti-1352	360	11	of	of	ADP
dti-1352	360	12	scopolamine	scopolamine	NOUN
dti-1352	360	13	and	and	CCONJ
dti-1352	360	14	mk-801	mk-801	PROPN
dti-1352	360	15	produces	produce	VERB
dti-1352	360	16	a	a	DET
dti-1352	360	17	short	short	ADJ
dti-1352	360	18	-	-	PUNCT
dti-1352	360	19	term	term	NOUN
dti-1352	360	20	amnesia	amnesia	NOUN
dti-1352	360	21	for	for	ADP
dti-1352	360	22	the	the	DET
dti-1352	360	23	elevated	elevated	ADJ
dti-1352	360	24	plus	plus	NOUN
dti-1352	360	25	-	-	PUNCT
dti-1352	360	26	maze	maze	NOUN
dti-1352	360	27	in	in	ADP
dti-1352	360	28	mice	mouse	NOUN
dti-1352	360	29	.	.	PUNCT
dti-1352	361	1	behav	behav	NOUN
dti-1352	361	2	brain	brain	NOUN
dti-1352	361	3	res	re	NOUN
dti-1352	361	4	.	.	PUNCT
dti-1352	362	1	1998;91:83–9	1998;91:83–9	NUM
dti-1352	362	2	.	.	PUNCT
dti-1352	363	1	32	32	NUM
dti-1352	363	2	.	.	PUNCT
dti-1352	364	1	savlı	savlı	PROPN
dti-1352	364	2	h	h	PROPN
dti-1352	364	3	,	,	PUNCT
dti-1352	364	4	aalto	aalto	PROPN
dti-1352	364	5	y	y	PROPN
dti-1352	364	6	,	,	PUNCT
dti-1352	364	7	nagy	nagy	PROPN
dti-1352	364	8	b	b	PROPN
dti-1352	364	9	,	,	PUNCT
dti-1352	364	10	knuutila	knuutila	PROPN
dti-1352	364	11	s	s	PROPN
dti-1352	364	12	,	,	PUNCT
dti-1352	364	13	pakkala	pakkala	PROPN
dti-1352	364	14	s.	s.	PROPN
dti-1352	364	15	gene	gene	NOUN
dti-1352	364	16	expression	expression	NOUN
dti-1352	364	17	analysis	analysis	NOUN
dti-1352	364	18	of	of	ADP
dti-1352	364	19	1,25(oh)2d3	1,25(oh)2d3	NUM
dti-1352	364	20	dependent	dependent	ADJ
dti-1352	364	21	differentiation	differentiation	NOUN
dti-1352	364	22	of	of	ADP
dti-1352	364	23	hl-60	hl-60	PUNCT
dti-1352	364	24	cells	cell	NOUN
dti-1352	364	25	—	—	PUNCT
dti-1352	364	26	a	a	DET
dti-1352	364	27	cdna	cdna	PROPN
dti-1352	364	28	array	array	NOUN
dti-1352	364	29	study	study	NOUN
dti-1352	364	30	.	.	PUNCT
dti-1352	365	1	br	br	PROPN
dti-1352	365	2	j	j	PROPN
dti-1352	365	3	haematol	haematol	NOUN
dti-1352	365	4	.	.	PUNCT
dti-1352	366	1	2002;118(4):1065–72	2002;118(4):1065–72	NUM
dti-1352	366	2	.	.	NOUN
dti-1352	367	1	33	33	NUM
dti-1352	367	2	.	.	PUNCT
dti-1352	368	1	savlı	savlı	PROPN
dti-1352	368	2	h	h	NOUN
dti-1352	368	3	,	,	PUNCT
dti-1352	368	4	karadenizli	karadenizli	ADJ
dti-1352	368	5	a	a	PRON
dti-1352	368	6	,	,	PUNCT
dti-1352	368	7	kolaylı	kolaylı	PROPN
dti-1352	368	8	f	f	PROPN
dti-1352	368	9	,	,	PUNCT
dti-1352	368	10	gundes	gunde	NOUN
dti-1352	368	11	s	s	PROPN
dti-1352	368	12	,	,	PUNCT
dti-1352	368	13	ozbek	ozbek	NOUN
dti-1352	368	14	u	u	PROPN
dti-1352	368	15	,	,	PUNCT
dti-1352	368	16	vahaboglu	vahaboglu	PROPN
dti-1352	368	17	h.	h.	PROPN
dti-1352	368	18	expression	expression	NOUN
dti-1352	368	19	stability	stability	NOUN
dti-1352	368	20	of	of	ADP
dti-1352	368	21	six	six	NUM
dti-1352	368	22	housekeeping	housekeeping	NOUN
dti-1352	368	23	genes	gene	NOUN
dti-1352	368	24	:	:	PUNCT
dti-1352	368	25	a	a	DET
dti-1352	368	26	proposal	proposal	NOUN
dti-1352	368	27	for	for	ADP
dti-1352	368	28	resistance	resistance	NOUN
dti-1352	368	29	gene	gene	NOUN
dti-1352	368	30	quantification	quantification	NOUN
dti-1352	368	31	studies	study	NOUN
dti-1352	368	32	of	of	ADP
dti-1352	368	33	pseudomonas	pseudomona	NOUN
dti-1352	368	34	aeruginosa	aeruginosa	NOUN
dti-1352	368	35	by	by	ADP
dti-1352	368	36	real	real	ADJ
dti-1352	368	37	-	-	PUNCT
dti-1352	368	38	time	time	NOUN
dti-1352	368	39	quantitative	quantitative	ADJ
dti-1352	368	40	rt	rt	NOUN
dti-1352	368	41	-	-	PUNCT
dti-1352	368	42	pcr	pcr	NOUN
dti-1352	368	43	.	.	PUNCT
dti-1352	369	1	j	j	PROPN
dti-1352	369	2	med	med	PROPN
dti-1352	369	3	microbiol	microbiol	PROPN
dti-1352	369	4	.	.	PUNCT
dti-1352	370	1	2003;52:403–8	2003;52:403–8	NUM
dti-1352	370	2	.	.	PUNCT
dti-1352	371	1	34	34	NUM
dti-1352	371	2	.	.	PUNCT
dti-1352	371	3	alfonso	alfonso	PROPN
dti-1352	371	4	j	j	PROPN
dti-1352	371	5	,	,	PUNCT
dti-1352	371	6	frasch	frasch	VERB
dti-1352	371	7	ac	ac	PROPN
dti-1352	371	8	,	,	PUNCT
dti-1352	371	9	flugge	flugge	PROPN
dti-1352	371	10	g.	g.	PROPN
dti-1352	371	11	chronic	chronic	PROPN
dti-1352	371	12	stress	stress	NOUN
dti-1352	371	13	,	,	PUNCT
dti-1352	371	14	depression	depression	NOUN
dti-1352	371	15	and	and	CCONJ
dti-1352	371	16	antidepressants	antidepressant	NOUN
dti-1352	371	17	:	:	PUNCT
dti-1352	371	18	effects	effect	NOUN
dti-1352	371	19	on	on	ADP
dti-1352	371	20	gene	gene	NOUN
dti-1352	371	21	transcription	transcription	NOUN
dti-1352	371	22	in	in	ADP
dti-1352	371	23	the	the	DET
dti-1352	371	24	hippocampus	hippocampus	NOUN
dti-1352	371	25	.	.	PUNCT
dti-1352	372	1	rev	rev	PROPN
dti-1352	372	2	neurosci	neurosci	PROPN
dti-1352	372	3	.	.	PUNCT
dti-1352	373	1	2005;16:43–56	2005;16:43–56	NUM
dti-1352	373	2	.	.	PUNCT
dti-1352	374	1	35	35	NUM
dti-1352	374	2	.	.	PUNCT
dti-1352	374	3	song	song	PROPN
dti-1352	374	4	l	l	PROPN
dti-1352	374	5	,	,	PUNCT
dti-1352	374	6	che	che	PROPN
dti-1352	374	7	w	w	PROPN
dti-1352	374	8	,	,	PUNCT
dti-1352	374	9	min	min	PROPN
dti-1352	374	10	-	-	PUNCT
dti-1352	374	11	wei	wei	PROPN
dti-1352	374	12	w	w	PROPN
dti-1352	374	13	,	,	PUNCT
dti-1352	374	14	murakami	murakami	PROPN
dti-1352	374	15	y	y	PROPN
dti-1352	374	16	,	,	PUNCT
dti-1352	374	17	matsumoto	matsumoto	PROPN
dti-1352	374	18	k.	k.	PROPN
dti-1352	374	19	impairment	impairment	PROPN
dti-1352	374	20	of	of	ADP
dti-1352	374	21	the	the	DET
dti-1352	374	22	spatial	spatial	ADJ
dti-1352	374	23	learning	learning	NOUN
dti-1352	374	24	and	and	CCONJ
dti-1352	374	25	memory	memory	NOUN
dti-1352	374	26	induced	induce	VERB
dti-1352	374	27	by	by	ADP
dti-1352	374	28	learned	learn	VERB
dti-1352	374	29	helplessness	helplessness	NOUN
dti-1352	374	30	and	and	CCONJ
dti-1352	374	31	chronic	chronic	ADJ
dti-1352	374	32	mild	mild	ADJ
dti-1352	374	33	stress	stress	NOUN
dti-1352	374	34	.	.	PUNCT
dti-1352	375	1	pharmacol	pharmacol	PROPN
dti-1352	375	2	biochem	biochem	PROPN
dti-1352	375	3	behav	behav	NOUN
dti-1352	375	4	.	.	PUNCT
dti-1352	376	1	2006;83:186–93	2006;83:186–93	X
dti-1352	376	2	.	.	PROPN
dti-1352	377	1	36	36	NUM
dti-1352	377	2	.	.	PUNCT
dti-1352	378	1	papp	papp	PROPN
dti-1352	378	2	m	m	PROPN
dti-1352	378	3	,	,	PUNCT
dti-1352	378	4	gruca	gruca	VERB
dti-1352	378	5	p	p	NOUN
dti-1352	378	6	,	,	PUNCT
dti-1352	378	7	boyer	boyer	PROPN
dti-1352	378	8	pa	pa	PROPN
dti-1352	378	9	,	,	PUNCT
dti-1352	378	10	mocaer	mocaer	PROPN
dti-1352	378	11	e.	e.	PROPN
dti-1352	378	12	effect	effect	PROPN
dti-1352	378	13	of	of	ADP
dti-1352	378	14	agomelatine	agomelatine	NOUN
dti-1352	378	15	in	in	ADP
dti-1352	378	16	the	the	DET
dti-1352	378	17	chronic	chronic	ADJ
dti-1352	378	18	mild	mild	ADJ
dti-1352	378	19	stress	stress	NOUN
dti-1352	378	20	model	model	NOUN
dti-1352	378	21	of	of	ADP
dti-1352	378	22	depression	depression	NOUN
dti-1352	378	23	in	in	ADP
dti-1352	378	24	the	the	DET
dti-1352	378	25	rat	rat	NOUN
dti-1352	378	26	.	.	PROPN
dti-1352	378	27	neuropsychopharmacol	neuropsychopharmacol	PROPN
dti-1352	378	28	.	.	PUNCT
dti-1352	379	1	2003;28:694–703	2003;28:694–703	NOUN
dti-1352	379	2	.	.	PUNCT
dti-1352	380	1	37	37	NUM
dti-1352	380	2	.	.	PUNCT
dti-1352	380	3	ying	ying	PROPN
dti-1352	380	4	sw	sw	PROPN
dti-1352	380	5	,	,	PUNCT
dti-1352	380	6	rusak	rusak	ADJ
dti-1352	380	7	b	b	NOUN
dti-1352	380	8	,	,	PUNCT
dti-1352	380	9	delagrange	delagrange	NOUN
dti-1352	380	10	p	p	NOUN
dti-1352	380	11	,	,	PUNCT
dti-1352	380	12	mocaer	mocaer	PROPN
dti-1352	380	13	e	e	PROPN
dti-1352	380	14	,	,	PUNCT
dti-1352	380	15	renard	renard	VERB
dti-1352	380	16	p	p	NOUN
dti-1352	380	17	,	,	PUNCT
dti-1352	380	18	guardiolalemaitre	guardiolalemaitre	PROPN
dti-1352	380	19	b.	b.	PROPN
dti-1352	380	20	melatonin	melatonin	PROPN
dti-1352	380	21	analogues	analogues	PROPN
dti-1352	380	22	as	as	ADP
dti-1352	380	23	agonists	agonist	NOUN
dti-1352	380	24	and	and	CCONJ
dti-1352	380	25	antagonists	antagonist	NOUN
dti-1352	380	26	in	in	ADP
dti-1352	380	27	the	the	DET
dti-1352	380	28	circadian	circadian	ADJ
dti-1352	380	29	system	system	NOUN
dti-1352	380	30	and	and	CCONJ
dti-1352	380	31	other	other	ADJ
dti-1352	380	32	brain	brain	NOUN
dti-1352	380	33	areas	area	NOUN
dti-1352	380	34	.	.	PUNCT
dti-1352	381	1	eur	eur	PROPN
dti-1352	381	2	j	j	PROPN
dti-1352	381	3	pharmacol	pharmacol	PROPN
dti-1352	381	4	.	.	PUNCT
dti-1352	382	1	1996;296:33–42	1996;296:33–42	NUM
dti-1352	382	2	.	.	PROPN
dti-1352	382	3	38	38	NUM
dti-1352	382	4	.	.	PUNCT
dti-1352	383	1	bonnefond	bonnefond	PROPN
dti-1352	383	2	c	c	NOUN
dti-1352	383	3	,	,	PUNCT
dti-1352	383	4	martinet	martinet	PROPN
dti-1352	383	5	l	l	PROPN
dti-1352	383	6	,	,	PUNCT
dti-1352	383	7	lesieur	lesieur	PROPN
dti-1352	383	8	d	d	PROPN
dti-1352	383	9	,	,	PUNCT
dti-1352	383	10	adam	adam	PROPN
dti-1352	383	11	g	g	PROPN
dti-1352	383	12	,	,	PUNCT
dti-1352	383	13	guardiola	guardiola	NOUN
dti-1352	383	14	-	-	PUNCT
dti-1352	383	15	lemaître	lemaître	NOUN
dti-1352	383	16	b.	b.	NOUN
dti-1352	383	17	characterization	characterization	NOUN
dti-1352	383	18	of	of	ADP
dti-1352	383	19	s-20098	s-20098	PROPN
dti-1352	383	20	,	,	PUNCT
dti-1352	383	21	a	a	DET
dti-1352	383	22	new	new	ADJ
dti-1352	383	23	melatonin	melatonin	NOUN
dti-1352	383	24	analogue	analogue	NOUN
dti-1352	383	25	.	.	PUNCT
dti-1352	384	1	in	in	ADP
dti-1352	384	2	:	:	PUNCT
dti-1352	384	3	touitou	touitou	PROPN
dti-1352	384	4	y	y	PROPN
dti-1352	384	5	,	,	PUNCT
dti-1352	384	6	arendt	arendt	PROPN
dti-1352	384	7	j	j	PROPN
dti-1352	384	8	,	,	PUNCT
dti-1352	384	9	pevet	pevet	NOUN
dti-1352	384	10	p	p	X
dti-1352	384	11	,	,	PUNCT
dti-1352	384	12	eds	eds	PROPN
dti-1352	384	13	.	.	PUNCT
dti-1352	384	14	melatonin	melatonin	NOUN
dti-1352	384	15	and	and	CCONJ
dti-1352	384	16	the	the	DET
dti-1352	384	17	pineal	pineal	NOUN
dti-1352	384	18	gland	gland	NOUN
dti-1352	384	19	.	.	PUNCT
dti-1352	385	1	amsterdam	amsterdam	PROPN
dti-1352	385	2	:	:	PUNCT
dti-1352	385	3	elsevier	elsevi	ADJ
dti-1352	385	4	science	science	NOUN
dti-1352	385	5	publishers	publisher	NOUN
dti-1352	385	6	;	;	PUNCT
dti-1352	385	7	1993:123–6	1993:123–6	X
dti-1352	385	8	.	.	NOUN
dti-1352	385	9	39	39	NUM
dti-1352	385	10	.	.	PUNCT
dti-1352	386	1	guardiola	guardiola	NOUN
dti-1352	386	2	-	-	PUNCT
dti-1352	386	3	lemaitre	lemaitre	PROPN
dti-1352	386	4	b.	b.	PROPN
dti-1352	386	5	melatoninergic	melatoninergic	ADJ
dti-1352	386	6	receptor	receptor	NOUN
dti-1352	386	7	agonists	agonist	NOUN
dti-1352	386	8	and	and	CCONJ
dti-1352	386	9	antagonists	antagonist	NOUN
dti-1352	386	10	:	:	PUNCT
dti-1352	386	11	pharmacological	pharmacological	ADJ
dti-1352	386	12	aspects	aspect	NOUN
dti-1352	386	13	and	and	CCONJ
dti-1352	386	14	therapeutic	therapeutic	ADJ
dti-1352	386	15	perspective	perspective	NOUN
dti-1352	386	16	.	.	PUNCT
dti-1352	387	1	ann	ann	PROPN
dti-1352	387	2	pharm	pharm	PROPN
dti-1352	387	3	fr	fr	PROPN
dti-1352	387	4	.	.	PUNCT
dti-1352	388	1	2005;63:385–400	2005;63:385–400	X
dti-1352	388	2	.	.	PUNCT
dti-1352	389	1	40	40	NUM
dti-1352	389	2	.	.	PUNCT
dti-1352	390	1	bianchi	bianchi	PROPN
dti-1352	390	2	m	m	PROPN
dti-1352	390	3	,	,	PUNCT
dti-1352	390	4	hagan	hagan	PROPN
dti-1352	390	5	jj	jj	PROPN
dti-1352	390	6	,	,	PUNCT
dti-1352	390	7	heidbreder	heidbreder	NOUN
dti-1352	390	8	ca	ca	NOUN
dti-1352	390	9	.	.	PUNCT
dti-1352	391	1	neuronal	neuronal	ADJ
dti-1352	391	2	plasticity	plasticity	NOUN
dti-1352	391	3	,	,	PUNCT
dti-1352	391	4	stress	stress	NOUN
dti-1352	391	5	and	and	CCONJ
dti-1352	391	6	depression	depression	NOUN
dti-1352	391	7	:	:	PUNCT
dti-1352	391	8	involvement	involvement	NOUN
dti-1352	391	9	of	of	ADP
dti-1352	391	10	the	the	DET
dti-1352	391	11	cytoskeletal	cytoskeletal	ADJ
dti-1352	391	12	microtubular	microtubular	ADJ
dti-1352	391	13	system	system	NOUN
dti-1352	391	14	?	?	PUNCT
dti-1352	392	1	curr	curr	PROPN
dti-1352	392	2	drug	drug	NOUN
dti-1352	392	3	targets	target	NOUN
dti-1352	392	4	cns	cns	PROPN
dti-1352	392	5	neurol	neurol	PROPN
dti-1352	392	6	disord	disord	NOUN
dti-1352	392	7	.	.	PUNCT
dti-1352	393	1	2005;4:597–611	2005;4:597–611	NUM
dti-1352	393	2	.	.	PUNCT
dti-1352	394	1	41	41	NUM
dti-1352	394	2	.	.	PUNCT
dti-1352	395	1	warner	warner	NOUN
dti-1352	395	2	-	-	PUNCT
dti-1352	395	3	schmidt	schmidt	PROPN
dti-1352	395	4	jl	jl	PROPN
dti-1352	395	5	,	,	PUNCT
dti-1352	395	6	duman	duman	PROPN
dti-1352	395	7	rs	rs	PROPN
dti-1352	395	8	.	.	PUNCT
dti-1352	396	1	hippocampal	hippocampal	ADJ
dti-1352	396	2	neurogenesis	neurogenesis	NOUN
dti-1352	396	3	:	:	PUNCT
dti-1352	396	4	opposing	oppose	VERB
dti-1352	396	5	effects	effect	NOUN
dti-1352	396	6	of	of	ADP
dti-1352	396	7	stress	stress	NOUN
dti-1352	396	8	and	and	CCONJ
dti-1352	396	9	antidepressant	antidepressant	ADJ
dti-1352	396	10	treatment	treatment	NOUN
dti-1352	396	11	.	.	PUNCT
dti-1352	397	1	hippocampus	hippocampus	NOUN
dti-1352	397	2	.	.	PUNCT
dti-1352	398	1	2006;16:239–49	2006;16:239–49	NUM
dti-1352	398	2	.	.	PUNCT
dti-1352	399	1	42	42	NUM
dti-1352	399	2	.	.	PUNCT
dti-1352	400	1	sanchez	sanchez	PROPN
dti-1352	400	2	c	c	PROPN
dti-1352	400	3	,	,	PUNCT
dti-1352	400	4	hyttel	hyttel	PROPN
dti-1352	400	5	j.	j.	PROPN
dti-1352	400	6	comparison	comparison	NOUN
dti-1352	400	7	of	of	ADP
dti-1352	400	8	the	the	DET
dti-1352	400	9	effects	effect	NOUN
dti-1352	400	10	of	of	ADP
dti-1352	400	11	antidepressants	antidepressant	NOUN
dti-1352	400	12	and	and	CCONJ
dti-1352	400	13	their	their	PRON
dti-1352	400	14	metabolites	metabolite	NOUN
dti-1352	400	15	on	on	ADP
dti-1352	400	16	reuptake	reuptake	NOUN
dti-1352	400	17	of	of	ADP
dti-1352	400	18	biogenic	biogenic	ADJ
dti-1352	400	19	amines	amine	NOUN
dti-1352	400	20	and	and	CCONJ
dti-1352	400	21	on	on	ADP
dti-1352	400	22	receptor	receptor	NOUN
dti-1352	400	23	binding	bind	VERB
dti-1352	400	24	.	.	PUNCT
dti-1352	401	1	cell	cell	NOUN
dti-1352	401	2	mol	mol	ADP
dti-1352	401	3	neurobiol	neurobiol	NOUN
dti-1352	401	4	.	.	PUNCT
dti-1352	402	1	1999;19:467–89	1999;19:467–89	X
dti-1352	402	2	.	.	PUNCT
dti-1352	403	1	43	43	NUM
dti-1352	403	2	.	.	PUNCT
dti-1352	404	1	kennaway	kennaway	PROPN
dti-1352	404	2	dj	dj	PROPN
dti-1352	404	3	,	,	PUNCT
dti-1352	404	4	moyer	moyer	PROPN
dti-1352	404	5	rw	rw	PROPN
dti-1352	404	6	.	.	PROPN
dti-1352	404	7	serotonin	serotonin	VERB
dti-1352	404	8	5	5	NUM
dti-1352	404	9	-	-	PUNCT
dti-1352	404	10	ht2c	ht2c	NOUN
dti-1352	404	11	agonists	agonist	NOUN
dti-1352	404	12	mimic	mimic	VERB
dti-1352	404	13	the	the	DET
dti-1352	404	14	effect	effect	NOUN
dti-1352	404	15	of	of	ADP
dti-1352	404	16	light	light	ADJ
dti-1352	404	17	pulses	pulse	NOUN
dti-1352	404	18	on	on	ADP
dti-1352	404	19	circadian	circadian	ADJ
dti-1352	404	20	rhythms	rhythm	NOUN
dti-1352	404	21	.	.	PUNCT
dti-1352	405	1	brain	brain	NOUN
dti-1352	405	2	res	re	NOUN
dti-1352	405	3	.	.	PUNCT
dti-1352	406	1	1998;806:257–70	1998;806:257–70	NUM
dti-1352	406	2	.	.	PUNCT
dti-1352	407	1	44	44	NUM
dti-1352	407	2	.	.	PUNCT
dti-1352	408	1	wirz	wirz	PROPN
dti-1352	408	2	-	-	PUNCT
dti-1352	408	3	justice	justice	PROPN
dti-1352	408	4	a.	a.	NOUN
dti-1352	408	5	biological	biological	ADJ
dti-1352	408	6	rhythms	rhythm	NOUN
dti-1352	408	7	in	in	ADP
dti-1352	408	8	mood	mood	NOUN
dti-1352	408	9	disorders	disorder	NOUN
dti-1352	408	10	.	.	PUNCT
dti-1352	409	1	in	in	ADP
dti-1352	409	2	:	:	PUNCT
dti-1352	409	3	bloom	bloom	PROPN
dti-1352	409	4	fe	fe	PROPN
dti-1352	409	5	,	,	PUNCT
dti-1352	409	6	kupfer	kupfer	PROPN
dti-1352	409	7	dj	dj	PROPN
dti-1352	409	8	,	,	PUNCT
dti-1352	409	9	eds	ed	NOUN
dti-1352	409	10	.	.	PUNCT
dti-1352	409	11	psychopharmacology	psychopharmacology	NOUN
dti-1352	409	12	:	:	PUNCT
dti-1352	409	13	the	the	DET
dti-1352	409	14	fourth	fourth	ADJ
dti-1352	409	15	generation	generation	NOUN
dti-1352	409	16	of	of	ADP
dti-1352	409	17	progress	progress	NOUN
dti-1352	409	18	.	.	PUNCT
dti-1352	410	1	new	new	PROPN
dti-1352	410	2	york	york	PROPN
dti-1352	410	3	:	:	PUNCT
dti-1352	410	4	raven	raven	PROPN
dti-1352	410	5	pres	pres	PROPN
dti-1352	410	6	;	;	PUNCT
dti-1352	410	7	1995:999–1017	1995:999–1017	NUM
dti-1352	410	8	.	.	NOUN
dti-1352	410	9	45	45	NUM
dti-1352	410	10	.	.	PUNCT
dti-1352	411	1	wehr	wehr	PROPN
dti-1352	411	2	ta	ta	PROPN
dti-1352	411	3	,	,	PUNCT
dti-1352	411	4	wirz	wirz	PROPN
dti-1352	411	5	-	-	PUNCT
dti-1352	411	6	justice	justice	PROPN
dti-1352	411	7	a.	a.	PROPN
dti-1352	411	8	circadian	circadian	PROPN
dti-1352	411	9	rhythm	rhythm	PROPN
dti-1352	411	10	mechanisms	mechanism	NOUN
dti-1352	411	11	in	in	ADP
dti-1352	411	12	affective	affective	ADJ
dti-1352	411	13	illness	illness	NOUN
dti-1352	411	14	and	and	CCONJ
dti-1352	411	15	in	in	ADP
dti-1352	411	16	antidepressant	antidepressant	ADJ
dti-1352	411	17	drug	drug	NOUN
dti-1352	411	18	action	action	NOUN
dti-1352	411	19	.	.	PUNCT
dti-1352	412	1	pharmacopsychiatry.1982;15:31–9	pharmacopsychiatry.1982;15:31–9	NOUN
dti-1352	412	2	.	.	PUNCT
dti-1352	413	1	46	46	NUM
dti-1352	413	2	.	.	PUNCT
dti-1352	414	1	branchi	branchi	PROPN
dti-1352	414	2	i	i	PROPN
dti-1352	414	3	,	,	PUNCT
dti-1352	414	4	francia	francia	PROPN
dti-1352	414	5	n	n	CCONJ
dti-1352	414	6	,	,	PUNCT
dti-1352	414	7	alleva	alleva	PROPN
dti-1352	414	8	e.	e.	PROPN
dti-1352	414	9	epigenetic	epigenetic	PROPN
dti-1352	414	10	control	control	NOUN
dti-1352	414	11	of	of	ADP
dti-1352	414	12	neurobehavioural	neurobehavioural	ADJ
dti-1352	414	13	plasticity	plasticity	NOUN
dti-1352	414	14	:	:	PUNCT
dti-1352	414	15	the	the	DET
dti-1352	414	16	role	role	NOUN
dti-1352	414	17	of	of	ADP
dti-1352	414	18	neurotrophins	neurotrophin	NOUN
dti-1352	414	19	.	.	PUNCT
dti-1352	415	1	behav	behav	NOUN
dti-1352	415	2	pharmacol	pharmacol	PROPN
dti-1352	415	3	.	.	PUNCT
dti-1352	416	1	2004;15:353–62	2004;15:353–62	NUM
dti-1352	416	2	.	.	PROPN
dti-1352	417	1	47	47	NUM
dti-1352	417	2	.	.	PUNCT
dti-1352	418	1	schulman	schulman	PROPN
dti-1352	418	2	h.	h.	PROPN
dti-1352	418	3	protein	protein	NOUN
dti-1352	418	4	phosphorylation	phosphorylation	NOUN
dti-1352	418	5	in	in	ADP
dti-1352	418	6	neuronal	neuronal	ADJ
dti-1352	418	7	plasticity	plasticity	NOUN
dti-1352	418	8	and	and	CCONJ
dti-1352	418	9	gene	gene	NOUN
dti-1352	418	10	expression	expression	NOUN
dti-1352	418	11	.	.	PUNCT
dti-1352	419	1	curr	curr	PROPN
dti-1352	419	2	opin	opin	PROPN
dti-1352	419	3	neurobiol	neurobiol	NOUN
dti-1352	419	4	.	.	PUNCT
dti-1352	420	1	1995;5:375–81	1995;5:375–81	NUM
dti-1352	420	2	.	.	PUNCT
dti-1352	420	3	http://www.la-press.com	http://www.la-press.com	X
dti-1352	420	4	agomelatin	agomelatin	PROPN
dti-1352	420	5	improves	improve	VERB
dti-1352	420	6	memory	memory	NOUN
dti-1352	420	7	in	in	ADP
dti-1352	420	8	stress	stress	NOUN
dti-1352	420	9	exposed	expose	VERB
dti-1352	420	10	mice	mouse	NOUN
dti-1352	420	11	21drug	21drug	PUNCT
dti-1352	420	12	target	target	NOUN
dti-1352	420	13	insights	insight	NOUN
dti-1352	420	14	2014:8	2014:8	NUM
dti-1352	420	15	48	48	NUM
dti-1352	420	16	.	.	PUNCT
dti-1352	421	1	duman	duman	PROPN
dti-1352	421	2	rs	rs	PROPN
dti-1352	421	3	,	,	PUNCT
dti-1352	421	4	malberg	malberg	PROPN
dti-1352	421	5	j	j	PROPN
dti-1352	421	6	,	,	PUNCT
dti-1352	421	7	nakagawa	nakagawa	PROPN
dti-1352	421	8	s	s	PROPN
dti-1352	421	9	,	,	PUNCT
dti-1352	421	10	d’sa	d’sa	PROPN
dti-1352	421	11	c.	c.	NOUN
dti-1352	421	12	neuronal	neuronal	ADJ
dti-1352	421	13	plasticity	plasticity	NOUN
dti-1352	421	14	and	and	CCONJ
dti-1352	421	15	survival	survival	NOUN
dti-1352	421	16	in	in	ADP
dti-1352	421	17	mood	mood	NOUN
dti-1352	421	18	disorders	disorder	NOUN
dti-1352	421	19	.	.	PUNCT
dti-1352	422	1	biol	biol	PROPN
dti-1352	422	2	psychiatry	psychiatry	NOUN
dti-1352	422	3	.	.	PUNCT
dti-1352	423	1	2000;48:732–9	2000;48:732–9	NUM
dti-1352	423	2	.	.	PUNCT
dti-1352	423	3	49	49	NUM
dti-1352	423	4	.	.	PUNCT
dti-1352	424	1	molteni	molteni	PROPN
dti-1352	424	2	r	r	PROPN
dti-1352	424	3	,	,	PUNCT
dti-1352	424	4	calabrese	calabrese	ADJ
dti-1352	424	5	f	f	PROPN
dti-1352	424	6	,	,	PUNCT
dti-1352	424	7	cattaneo	cattaneo	VERB
dti-1352	424	8	a	a	PRON
dti-1352	424	9	,	,	PUNCT
dti-1352	424	10	et	et	PROPN
dti-1352	424	11	al	al	PROPN
dti-1352	424	12	.	.	PROPN
dti-1352	424	13	acute	acute	PROPN
dti-1352	424	14	stress	stress	NOUN
dti-1352	424	15	responsiveness	responsiveness	NOUN
dti-1352	424	16	of	of	ADP
dti-1352	424	17	the	the	DET
dti-1352	424	18	neurotrophin	neurotrophin	PROPN
dti-1352	424	19	bdnf	bdnf	PROPN
dti-1352	424	20	in	in	ADP
dti-1352	424	21	the	the	DET
dti-1352	424	22	rat	rat	NOUN
dti-1352	424	23	hippocampus	hippocampus	NOUN
dti-1352	424	24	is	be	AUX
dti-1352	424	25	modulated	modulate	VERB
dti-1352	424	26	by	by	ADP
dti-1352	424	27	chronic	chronic	ADJ
dti-1352	424	28	treatment	treatment	NOUN
dti-1352	424	29	with	with	ADP
dti-1352	424	30	the	the	DET
dti-1352	424	31	antidepressant	antidepressant	ADJ
dti-1352	424	32	duloxetine	duloxetine	NOUN
dti-1352	424	33	.	.	PUNCT
dti-1352	425	1	neuropsychopharmacology	neuropsychopharmacology	NOUN
dti-1352	425	2	.	.	PUNCT
dti-1352	426	1	2009;34:1523–32	2009;34:1523–32	NUM
dti-1352	426	2	.	.	PUNCT
dti-1352	427	1	50	50	NUM
dti-1352	427	2	.	.	PUNCT
dti-1352	427	3	ernfors	ernfor	NOUN
dti-1352	427	4	p	p	X
dti-1352	427	5	,	,	PUNCT
dti-1352	427	6	ibáñez	ibáñez	NOUN
dti-1352	427	7	cf	cf	NOUN
dti-1352	427	8	,	,	PUNCT
dti-1352	427	9	ebendal	ebendal	ADJ
dti-1352	427	10	t	t	PROPN
dti-1352	427	11	,	,	PUNCT
dti-1352	427	12	olson	olson	NOUN
dti-1352	427	13	l	l	PROPN
dti-1352	427	14	,	,	PUNCT
dti-1352	427	15	persson	persson	PROPN
dti-1352	427	16	h.	h.	PROPN
dti-1352	427	17	molecular	molecular	ADJ
dti-1352	427	18	cloning	cloning	NOUN
dti-1352	427	19	and	and	CCONJ
dti-1352	427	20	neurotrophic	neurotrophic	ADJ
dti-1352	427	21	activities	activity	NOUN
dti-1352	427	22	of	of	ADP
dti-1352	427	23	a	a	DET
dti-1352	427	24	protein	protein	NOUN
dti-1352	427	25	with	with	ADP
dti-1352	427	26	structural	structural	ADJ
dti-1352	427	27	similarities	similarity	NOUN
dti-1352	427	28	to	to	PART
dti-1352	427	29	nerve	nerve	NOUN
dti-1352	427	30	growth	growth	NOUN
dti-1352	427	31	factor	factor	NOUN
dti-1352	427	32	:	:	PUNCT
dti-1352	427	33	developmental	developmental	ADJ
dti-1352	427	34	and	and	CCONJ
dti-1352	427	35	topographical	topographical	ADJ
dti-1352	427	36	expression	expression	NOUN
dti-1352	427	37	in	in	ADP
dti-1352	427	38	the	the	DET
dti-1352	427	39	brain	brain	NOUN
dti-1352	427	40	.	.	PUNCT
dti-1352	428	1	proc	proc	PROPN
dti-1352	428	2	natl	natl	PROPN
dti-1352	428	3	acad	acad	PROPN
dti-1352	428	4	sci	sci	PROPN
dti-1352	428	5	u	u	PROPN
dti-1352	428	6	s	s	PART
dti-1352	428	7	a.	a.	NOUN
dti-1352	428	8	1990;87:5454–8	1990;87:5454–8	NOUN
dti-1352	428	9	.	.	PROPN
dti-1352	428	10	51	51	NUM
dti-1352	428	11	.	.	PUNCT
dti-1352	429	1	scaccianoce	scaccianoce	PROPN
dti-1352	429	2	s	s	PROPN
dti-1352	429	3	,	,	PUNCT
dti-1352	429	4	del	del	PROPN
dti-1352	429	5	bianco	bianco	PROPN
dti-1352	429	6	p	p	PROPN
dti-1352	429	7	,	,	PUNCT
dti-1352	429	8	caricasole	caricasole	NOUN
dti-1352	429	9	a	a	DET
dti-1352	429	10	,	,	PUNCT
dti-1352	429	11	nicoletti	nicoletti	NOUN
dti-1352	429	12	f	f	NUM
dti-1352	429	13	,	,	PUNCT
dti-1352	429	14	catalani	catalani	PROPN
dti-1352	429	15	a.	a.	NOUN
dti-1352	429	16	relationship	relationship	NOUN
dti-1352	429	17	between	between	ADP
dti-1352	429	18	learning	learning	NOUN
dti-1352	429	19	,	,	PUNCT
dti-1352	429	20	stress	stress	NOUN
dti-1352	429	21	and	and	CCONJ
dti-1352	429	22	hippocampal	hippocampal	ADJ
dti-1352	429	23	brain	brain	NOUN
dti-1352	429	24	-	-	PUNCT
dti-1352	429	25	derived	derive	VERB
dti-1352	429	26	neurotrophic	neurotrophic	ADJ
dti-1352	429	27	factor	factor	NOUN
dti-1352	429	28	.	.	PUNCT
dti-1352	430	1	neuroscience	neuroscience	NOUN
dti-1352	430	2	.	.	PUNCT
dti-1352	431	1	2003;121:825–8	2003;121:825–8	NUM
dti-1352	431	2	.	.	PROPN
dti-1352	432	1	52	52	NUM
dti-1352	432	2	.	.	PUNCT
dti-1352	433	1	lu	lu	PROPN
dti-1352	433	2	b.	b.	PROPN
dti-1352	433	3	bdnf	bdnf	PROPN
dti-1352	433	4	and	and	CCONJ
dti-1352	433	5	activity	activity	NOUN
dti-1352	433	6	-	-	PUNCT
dti-1352	433	7	dependent	dependent	ADJ
dti-1352	433	8	synaptic	synaptic	ADJ
dti-1352	433	9	modulation	modulation	NOUN
dti-1352	433	10	.	.	PUNCT
dti-1352	434	1	learn	learn	VERB
dti-1352	434	2	mem	mem	PROPN
dti-1352	434	3	.	.	PUNCT
dti-1352	435	1	2003;10:86–98	2003;10:86–98	NUM
dti-1352	435	2	.	.	PUNCT
dti-1352	436	1	53	53	NUM
dti-1352	436	2	.	.	PUNCT
dti-1352	436	3	mu	mu	PROPN
dti-1352	436	4	js	js	PROPN
dti-1352	436	5	,	,	PUNCT
dti-1352	436	6	li	li	PROPN
dti-1352	436	7	wp	wp	PROPN
dti-1352	436	8	,	,	PUNCT
dti-1352	436	9	yao	yao	PROPN
dti-1352	436	10	zb	zb	PROPN
dti-1352	436	11	,	,	PUNCT
dti-1352	436	12	zhou	zhou	PROPN
dti-1352	436	13	xf	xf	PROPN
dti-1352	436	14	.	.	PUNCT
dti-1352	436	15	deprivation	deprivation	NOUN
dti-1352	436	16	of	of	ADP
dti-1352	436	17	endogenous	endogenous	ADJ
dti-1352	436	18	brain	brain	NOUN
dti-1352	436	19	-	-	PUNCT
dti-1352	436	20	derived	derive	VERB
dti-1352	436	21	neurotrophic	neurotrophic	ADJ
dti-1352	436	22	factor	factor	NOUN
dti-1352	436	23	results	result	NOUN
dti-1352	436	24	in	in	ADP
dti-1352	436	25	impairment	impairment	NOUN
dti-1352	436	26	of	of	ADP
dti-1352	436	27	spatial	spatial	ADJ
dti-1352	436	28	learning	learning	NOUN
dti-1352	436	29	and	and	CCONJ
dti-1352	436	30	memory	memory	NOUN
dti-1352	436	31	in	in	ADP
dti-1352	436	32	adult	adult	NOUN
dti-1352	436	33	rats	rat	NOUN
dti-1352	436	34	.	.	PUNCT
dti-1352	437	1	brain	brain	NOUN
dti-1352	437	2	res	re	NOUN
dti-1352	437	3	.	.	PUNCT
dti-1352	438	1	1999;835:259–65	1999;835:259–65	NUM
dti-1352	438	2	.	.	PUNCT
dti-1352	439	1	54	54	NUM
dti-1352	439	2	.	.	PUNCT
dti-1352	440	1	aydemir	aydemir	PROPN
dti-1352	440	2	c	c	PROPN
dti-1352	440	3	,	,	PUNCT
dti-1352	440	4	yalcin	yalcin	PROPN
dti-1352	440	5	es	es	NOUN
dti-1352	440	6	,	,	PUNCT
dti-1352	440	7	aksaray	aksaray	VERB
dti-1352	440	8	s	s	NOUN
dti-1352	440	9	,	,	PUNCT
dti-1352	440	10	et	et	PROPN
dti-1352	440	11	al	al	PROPN
dti-1352	440	12	.	.	PUNCT
dti-1352	441	1	brain	brain	NOUN
dti-1352	441	2	-	-	PUNCT
dti-1352	441	3	derived	derive	VERB
dti-1352	441	4	neurotrophic	neurotrophic	ADJ
dti-1352	441	5	factor	factor	NOUN
dti-1352	441	6	(	(	PUNCT
dti-1352	441	7	bdnf	bdnf	PROPN
dti-1352	441	8	)	)	PUNCT
dti-1352	441	9	changes	change	NOUN
dti-1352	441	10	in	in	ADP
dti-1352	441	11	the	the	DET
dti-1352	441	12	serum	serum	NOUN
dti-1352	441	13	of	of	ADP
dti-1352	441	14	depressed	depressed	ADJ
dti-1352	441	15	women	woman	NOUN
dti-1352	441	16	.	.	PUNCT
dti-1352	442	1	prog	prog	PROPN
dti-1352	442	2	neuropsychopharmacol	neuropsychopharmacol	PROPN
dti-1352	442	3	biol	biol	PROPN
dti-1352	442	4	psychiatry	psychiatry	NOUN
dti-1352	442	5	.	.	PUNCT
dti-1352	443	1	2006;30:1256–60	2006;30:1256–60	NUM
dti-1352	443	2	.	.	PUNCT
dti-1352	444	1	55	55	NUM
dti-1352	444	2	.	.	PUNCT
dti-1352	445	1	bova	bova	PROPN
dti-1352	445	2	r	r	PROPN
dti-1352	445	3	,	,	PUNCT
dti-1352	445	4	micheli	micheli	PROPN
dti-1352	445	5	mr	mr	PROPN
dti-1352	445	6	,	,	PUNCT
dti-1352	445	7	qualadrucci	qualadrucci	PROPN
dti-1352	445	8	p	p	PROPN
dti-1352	445	9	,	,	PUNCT
dti-1352	445	10	zucconi	zucconi	PROPN
dti-1352	445	11	gg	gg	PROPN
dti-1352	445	12	.	.	PUNCT
dti-1352	446	1	bdnf	bdnf	PROPN
dti-1352	446	2	and	and	CCONJ
dti-1352	446	3	trkb	trkb	NOUN
dti-1352	446	4	mrnas	mrna	NOUN
dti-1352	446	5	oscillate	oscillate	VERB
dti-1352	446	6	in	in	ADP
dti-1352	446	7	rat	rat	NOUN
dti-1352	446	8	brain	brain	NOUN
dti-1352	446	9	during	during	ADP
dti-1352	446	10	the	the	DET
dti-1352	446	11	light	light	ADJ
dti-1352	446	12	-	-	PUNCT
dti-1352	446	13	dark	dark	NOUN
dti-1352	446	14	cycle	cycle	NOUN
dti-1352	446	15	.	.	PUNCT
dti-1352	447	1	brain	brain	NOUN
dti-1352	447	2	res	re	NOUN
dti-1352	447	3	mol	mol	ADP
dti-1352	447	4	brain	brain	NOUN
dti-1352	447	5	res	re	NOUN
dti-1352	447	6	.	.	PUNCT
dti-1352	448	1	1998;57:321–4	1998;57:321–4	NUM
dti-1352	448	2	.	.	PUNCT
dti-1352	449	1	56	56	NUM
dti-1352	449	2	.	.	PUNCT
dti-1352	450	1	molteni	molteni	PROPN
dti-1352	450	2	r	r	PROPN
dti-1352	450	3	,	,	PUNCT
dti-1352	450	4	calabrese	calabrese	ADJ
dti-1352	450	5	f	f	NOUN
dti-1352	450	6	,	,	PUNCT
dti-1352	450	7	pisoni	pisoni	PROPN
dti-1352	450	8	s	s	PROPN
dti-1352	450	9	,	,	PUNCT
dti-1352	450	10	et	et	PROPN
dti-1352	450	11	al	al	PROPN
dti-1352	450	12	.	.	PROPN
dti-1352	451	1	synergistic	synergistic	ADJ
dti-1352	451	2	mechanisms	mechanism	NOUN
dti-1352	451	3	in	in	ADP
dti-1352	451	4	the	the	DET
dti-1352	451	5	modulation	modulation	NOUN
dti-1352	451	6	of	of	ADP
dti-1352	451	7	the	the	DET
dti-1352	451	8	neurotrophin	neurotrophin	PROPN
dti-1352	451	9	bdnf	bdnf	PROPN
dti-1352	451	10	in	in	ADP
dti-1352	451	11	the	the	DET
dti-1352	451	12	rat	rat	NOUN
dti-1352	451	13	prefrontal	prefrontal	ADJ
dti-1352	451	14	cortex	cortex	NOUN
dti-1352	451	15	following	follow	VERB
dti-1352	451	16	acute	acute	PROPN
dti-1352	451	17	agomelatine	agomelatine	PROPN
dti-1352	451	18	administration	administration	PROPN
dti-1352	451	19	.	.	PUNCT
dti-1352	452	1	world	world	PROPN
dti-1352	452	2	j	j	PROPN
dti-1352	452	3	biol	biol	PROPN
dti-1352	452	4	psychiatry	psychiatry	NOUN
dti-1352	452	5	.	.	PUNCT
dti-1352	453	1	2010;11:148–53	2010;11:148–53	X
dti-1352	453	2	.	.	PROPN
dti-1352	453	3	57	57	NUM
dti-1352	453	4	.	.	PUNCT
dti-1352	453	5	soumier	soumier	PROPN
dti-1352	453	6	a	a	NOUN
dti-1352	453	7	,	,	PUNCT
dti-1352	453	8	banasr	banasr	PROPN
dti-1352	453	9	m	m	PROPN
dti-1352	453	10	,	,	PUNCT
dti-1352	453	11	lortet	lortet	PROPN
dti-1352	453	12	s	s	PROPN
dti-1352	453	13	,	,	PUNCT
dti-1352	453	14	et	et	PROPN
dti-1352	453	15	al	al	PROPN
dti-1352	453	16	.	.	PROPN
dti-1352	454	1	mechanisms	mechanism	NOUN
dti-1352	454	2	contributing	contribute	VERB
dti-1352	454	3	to	to	ADP
dti-1352	454	4	the	the	DET
dti-1352	454	5	phasedependent	phasedependent	NOUN
dti-1352	454	6	regulation	regulation	NOUN
dti-1352	454	7	of	of	ADP
dti-1352	454	8	neurogenesis	neurogenesis	NOUN
dti-1352	454	9	by	by	ADP
dti-1352	454	10	the	the	DET
dti-1352	454	11	novel	novel	ADJ
dti-1352	454	12	antidepressant	antidepressant	NOUN
dti-1352	454	13	,	,	PUNCT
dti-1352	454	14	agomelatine	agomelatine	NOUN
dti-1352	454	15	,	,	PUNCT
dti-1352	454	16	in	in	ADP
dti-1352	454	17	the	the	DET
dti-1352	454	18	adult	adult	NOUN
dti-1352	454	19	rat	rat	NOUN
dti-1352	454	20	hippocampus	hippocampus	NOUN
dti-1352	454	21	.	.	PUNCT
dti-1352	455	1	neuropsychopharmacol	neuropsychopharmacol	PROPN
dti-1352	455	2	.	.	PUNCT
dti-1352	456	1	2009;34:2390–403	2009;34:2390–403	X
dti-1352	456	2	.	.	PROPN
dti-1352	457	1	58	58	NUM
dti-1352	457	2	.	.	PUNCT
dti-1352	458	1	calabrese	calabrese	PROPN
dti-1352	458	2	f	f	PROPN
dti-1352	458	3	,	,	PUNCT
dti-1352	458	4	molteni	molteni	PROPN
dti-1352	458	5	r	r	PROPN
dti-1352	458	6	,	,	PUNCT
dti-1352	458	7	maj	maj	PROPN
dti-1352	458	8	pf	pf	PROPN
dti-1352	458	9	,	,	PUNCT
dti-1352	458	10	et	et	PROPN
dti-1352	458	11	al	al	PROPN
dti-1352	458	12	.	.	PROPN
dti-1352	459	1	chronic	chronic	ADJ
dti-1352	459	2	duloxetine	duloxetine	NOUN
dti-1352	459	3	treatment	treatment	NOUN
dti-1352	459	4	induces	induce	VERB
dti-1352	459	5	specific	specific	ADJ
dti-1352	459	6	changes	change	NOUN
dti-1352	459	7	in	in	ADP
dti-1352	459	8	the	the	DET
dti-1352	459	9	expression	expression	NOUN
dti-1352	459	10	of	of	ADP
dti-1352	459	11	bdnf	bdnf	ADJ
dti-1352	459	12	transcripts	transcript	NOUN
dti-1352	459	13	and	and	CCONJ
dti-1352	459	14	in	in	ADP
dti-1352	459	15	the	the	DET
dti-1352	459	16	subcellular	subcellular	ADJ
dti-1352	459	17	localization	localization	NOUN
dti-1352	459	18	of	of	ADP
dti-1352	459	19	the	the	DET
dti-1352	459	20	neurotrophin	neurotrophin	ADJ
dti-1352	459	21	protein	protein	NOUN
dti-1352	459	22	.	.	PUNCT
dti-1352	460	1	neuropsychopharmacology	neuropsychopharmacology	PROPN
dti-1352	460	2	.	.	PUNCT
dti-1352	461	1	2007;32:2351–9	2007;32:2351–9	PROPN
dti-1352	461	2	.	.	PROPN
dti-1352	462	1	59	59	NUM
dti-1352	462	2	.	.	PUNCT
dti-1352	462	3	morley	morley	PROPN
dti-1352	462	4	-	-	PUNCT
dti-1352	462	5	fletcher	fletcher	PROPN
dti-1352	462	6	s	s	PROPN
dti-1352	462	7	,	,	PUNCT
dti-1352	462	8	mairesse	mairesse	PROPN
dti-1352	462	9	j	j	PROPN
dti-1352	462	10	,	,	PUNCT
dti-1352	462	11	soumier	soumier	NOUN
dti-1352	462	12	a	a	NOUN
dti-1352	462	13	,	,	PUNCT
dti-1352	462	14	et	et	PROPN
dti-1352	462	15	al	al	PROPN
dti-1352	462	16	.	.	PROPN
dti-1352	463	1	chronic	chronic	PROPN
dti-1352	463	2	agomelatine	agomelatine	NOUN
dti-1352	463	3	treatment	treatment	NOUN
dti-1352	463	4	corrects	correct	NOUN
dti-1352	463	5	behavioral	behavioral	ADJ
dti-1352	463	6	,	,	PUNCT
dti-1352	463	7	cellular	cellular	ADJ
dti-1352	463	8	,	,	PUNCT
dti-1352	463	9	and	and	CCONJ
dti-1352	463	10	biochemical	biochemical	ADJ
dti-1352	463	11	abnormalities	abnormality	NOUN
dti-1352	463	12	induced	induce	VERB
dti-1352	463	13	by	by	ADP
dti-1352	463	14	prenatal	prenatal	ADJ
dti-1352	463	15	stress	stress	NOUN
dti-1352	463	16	in	in	ADP
dti-1352	463	17	rats	rat	NOUN
dti-1352	463	18	.	.	PUNCT
dti-1352	464	1	psychopharmacology	psychopharmacology	NOUN
dti-1352	464	2	(	(	PUNCT
dti-1352	464	3	berl	berl	PROPN
dti-1352	464	4	)	)	PUNCT
dti-1352	464	5	.	.	PUNCT
dti-1352	465	1	2011;217(3):301–13	2011;217(3):301–13	X
dti-1352	465	2	.	.	PROPN
dti-1352	465	3	60	60	NUM
dti-1352	465	4	.	.	PUNCT
dti-1352	466	1	ladurelle	ladurelle	PROPN
dti-1352	466	2	n	n	CCONJ
dti-1352	466	3	,	,	PUNCT
dti-1352	466	4	gabriel	gabriel	PROPN
dti-1352	466	5	c	c	PROPN
dti-1352	466	6	,	,	PUNCT
dti-1352	466	7	viggiano	viggiano	PROPN
dti-1352	466	8	a	a	PRON
dti-1352	466	9	,	,	PUNCT
dti-1352	466	10	mocaër	mocaër	PROPN
dti-1352	466	11	e	e	PROPN
dti-1352	466	12	,	,	PUNCT
dti-1352	466	13	baulieu	baulieu	PROPN
dti-1352	466	14	ee	ee	PROPN
dti-1352	466	15	,	,	PUNCT
dti-1352	466	16	bianchi	bianchi	PROPN
dti-1352	466	17	m.	m.	NOUN
dti-1352	466	18	agomelatine	agomelatine	PROPN
dti-1352	466	19	(	(	PUNCT
dti-1352	466	20	s20098	s20098	NOUN
dti-1352	466	21	)	)	PUNCT
dti-1352	466	22	modulates	modulate	VERB
dti-1352	466	23	the	the	DET
dti-1352	466	24	expression	expression	NOUN
dti-1352	466	25	of	of	ADP
dti-1352	466	26	cytoskeletal	cytoskeletal	ADJ
dti-1352	466	27	microtubular	microtubular	ADJ
dti-1352	466	28	proteins	protein	NOUN
dti-1352	466	29	,	,	PUNCT
dti-1352	466	30	synaptic	synaptic	ADJ
dti-1352	466	31	markers	marker	NOUN
dti-1352	466	32	and	and	CCONJ
dti-1352	466	33	bdnf	bdnf	PROPN
dti-1352	466	34	in	in	ADP
dti-1352	466	35	the	the	DET
dti-1352	466	36	rat	rat	NOUN
dti-1352	466	37	hippocampus	hippocampus	NOUN
dti-1352	466	38	,	,	PUNCT
dti-1352	466	39	amygdala	amygdala	NOUN
dti-1352	466	40	and	and	CCONJ
dti-1352	466	41	pfc	pfc	NOUN
dti-1352	466	42	.	.	PUNCT
dti-1352	467	1	psychopharmacology	psychopharmacology	NOUN
dti-1352	467	2	.	.	PUNCT
dti-1352	468	1	2012;221:493–509	2012;221:493–509	NOUN
dti-1352	468	2	.	.	PUNCT
dti-1352	469	1	61	61	NUM
dti-1352	469	2	.	.	PUNCT
dti-1352	470	1	barad	barad	PROPN
dti-1352	470	2	m	m	PROPN
dti-1352	470	3	,	,	PUNCT
dti-1352	470	4	bourtchouladze	bourtchouladze	VERB
dti-1352	470	5	r	r	NOUN
dti-1352	470	6	,	,	PUNCT
dti-1352	470	7	winder	winder	NOUN
dti-1352	470	8	dg	dg	PROPN
dti-1352	470	9	,	,	PUNCT
dti-1352	470	10	golan	golan	PROPN
dti-1352	470	11	h	h	PROPN
dti-1352	470	12	,	,	PUNCT
dti-1352	470	13	kandel	kandel	PROPN
dti-1352	470	14	e.	e.	PROPN
dti-1352	470	15	rolipram	rolipram	PROPN
dti-1352	470	16	,	,	PUNCT
dti-1352	470	17	a	a	DET
dti-1352	470	18	type	type	NOUN
dti-1352	470	19	iv	iv	NUM
dti-1352	470	20	specific	specific	ADJ
dti-1352	470	21	phosphodiesterase	phosphodiesterase	NOUN
dti-1352	470	22	inhibitor	inhibitor	NOUN
dti-1352	470	23	,	,	PUNCT
dti-1352	470	24	facilitates	facilitate	VERB
dti-1352	470	25	the	the	DET
dti-1352	470	26	establishment	establishment	NOUN
dti-1352	470	27	of	of	ADP
dti-1352	470	28	long	long	ADV
dti-1352	470	29	-	-	PUNCT
dti-1352	470	30	lasting	last	VERB
dti-1352	470	31	long	long	ADJ
dti-1352	470	32	-	-	PUNCT
dti-1352	470	33	term	term	NOUN
dti-1352	470	34	potentiation	potentiation	NOUN
dti-1352	470	35	and	and	CCONJ
dti-1352	470	36	improves	improve	VERB
dti-1352	470	37	memory	memory	NOUN
dti-1352	470	38	.	.	PUNCT
dti-1352	471	1	proc	proc	PROPN
dti-1352	471	2	natl	natl	PROPN
dti-1352	471	3	acad	acad	PROPN
dti-1352	471	4	sci	sci	PROPN
dti-1352	471	5	usa	usa	PROPN
dti-1352	471	6	.	.	PROPN
dti-1352	472	1	1998;95:15020–5	1998;95:15020–5	X
dti-1352	472	2	.	.	PROPN
dti-1352	473	1	62	62	NUM
dti-1352	473	2	.	.	PUNCT
dti-1352	474	1	thome	thome	PROPN
dti-1352	474	2	j	j	PROPN
dti-1352	474	3	,	,	PUNCT
dti-1352	474	4	sakai	sakai	PROPN
dti-1352	474	5	n	n	PROPN
dti-1352	474	6	,	,	PUNCT
dti-1352	474	7	shin	shin	PROPN
dti-1352	474	8	k	k	PROPN
dti-1352	474	9	,	,	PUNCT
dti-1352	474	10	et	et	PROPN
dti-1352	474	11	al	al	PROPN
dti-1352	474	12	.	.	PUNCT
dti-1352	474	13	camp	camp	PROPN
dti-1352	474	14	response	response	NOUN
dti-1352	474	15	element	element	NOUN
dti-1352	474	16	-	-	PUNCT
dti-1352	474	17	mediated	mediate	VERB
dti-1352	474	18	gene	gene	NOUN
dti-1352	474	19	transcription	transcription	NOUN
dti-1352	474	20	is	be	AUX
dti-1352	474	21	upregulated	upregulate	VERB
dti-1352	474	22	by	by	ADP
dti-1352	474	23	chronic	chronic	ADJ
dti-1352	474	24	antidepressant	antidepressant	ADJ
dti-1352	474	25	treatment	treatment	NOUN
dti-1352	474	26	.	.	PUNCT
dti-1352	475	1	j	j	PROPN
dti-1352	475	2	neurosci	neurosci	PROPN
dti-1352	475	3	.	.	PUNCT
dti-1352	476	1	2000;20:4030–6	2000;20:4030–6	X
dti-1352	476	2	.	.	PROPN
dti-1352	476	3	63	63	NUM
dti-1352	476	4	.	.	PUNCT
dti-1352	477	1	ferguson	ferguson	PROPN
dti-1352	477	2	jm	jm	PROPN
dti-1352	477	3	,	,	PUNCT
dti-1352	477	4	shrisvastava	shrisvastava	PROPN
dti-1352	477	5	rk	rk	PROPN
dti-1352	477	6	,	,	PUNCT
dti-1352	477	7	stahl	stahl	PROPN
dti-1352	477	8	sm	sm	PROPN
dti-1352	477	9	,	,	PUNCT
dti-1352	477	10	et	et	PROPN
dti-1352	477	11	al	al	PROPN
dti-1352	477	12	.	.	PROPN
dti-1352	477	13	re	re	PROPN
dti-1352	477	14	-	-	NOUN
dti-1352	477	15	emergence	emergence	NOUN
dti-1352	477	16	of	of	ADP
dti-1352	477	17	sexual	sexual	ADJ
dti-1352	477	18	dysfunction	dysfunction	NOUN
dti-1352	477	19	in	in	ADP
dti-1352	477	20	patients	patient	NOUN
dti-1352	477	21	with	with	ADP
dti-1352	477	22	major	major	ADJ
dti-1352	477	23	depressive	depressive	ADJ
dti-1352	477	24	disorder	disorder	NOUN
dti-1352	477	25	:	:	PUNCT
dti-1352	477	26	doubleblind	doubleblind	VERB
dti-1352	477	27	comparison	comparison	NOUN
dti-1352	477	28	of	of	ADP
dti-1352	477	29	nefadozone	nefadozone	NOUN
dti-1352	477	30	and	and	CCONJ
dti-1352	477	31	sertraline	sertraline	PROPN
dti-1352	477	32	.	.	PUNCT
dti-1352	478	1	j	j	PROPN
dti-1352	478	2	clin	clin	PROPN
dti-1352	478	3	psychiatry	psychiatry	PROPN
dti-1352	478	4	.	.	PUNCT
dti-1352	479	1	2001;62:24–9	2001;62:24–9	PROPN
dti-1352	479	2	.	.	PUNCT
dti-1352	479	3	http://www.la-press.com	http://www.la-press.com	X