id sid tid token lemma pos dti-1356 1 1 45drug 45drug NOUN dti-1356 1 2 target target NOUN dti-1356 1 3 insights insight VERB dti-1356 1 4 2014:8 2014:8 NUM dti-1356 1 5 open open ADJ dti-1356 1 6 access access NOUN dti-1356 1 7 : : PUNCT dti-1356 1 8 full full ADJ dti-1356 1 9 open open ADJ dti-1356 1 10 access access NOUN dti-1356 1 11 to to ADP dti-1356 1 12 this this PRON dti-1356 1 13 and and CCONJ dti-1356 1 14 thousands thousand NOUN dti-1356 1 15 of of ADP dti-1356 1 16 other other ADJ dti-1356 1 17 papers paper NOUN dti-1356 1 18 at at ADP dti-1356 1 19 http://www.la-press.com http://www.la-press.com X dti-1356 1 20 . . PUNCT dti-1356 2 1 drug drug NOUN dti-1356 2 2 target target NOUN dti-1356 2 3 insights insight VERB dti-1356 2 4 the the DET dti-1356 2 5 expression expression NOUN dti-1356 2 6 of of ADP dti-1356 2 7 serum serum NOUN dti-1356 2 8 antibodies antibody NOUN dti-1356 2 9 against against ADP dti-1356 2 10 gonadotropin gonadotropin NOUN dti-1356 2 11 - - PUNCT dti-1356 2 12 releasing release VERB dti-1356 2 13 hormone hormone NOUN dti-1356 2 14 ( ( PUNCT dti-1356 2 15 gnrh1 gnrh1 NOUN dti-1356 2 16 ) ) PUNCT dti-1356 2 17 , , PUNCT dti-1356 2 18 progonadoliberin-2 progonadoliberin-2 NUM dti-1356 2 19 , , PUNCT dti-1356 2 20 luteinizing luteinize VERB dti-1356 2 21 hormone hormone NOUN dti-1356 2 22 ( ( PUNCT dti-1356 2 23 lh lh PROPN dti-1356 2 24 ) ) PUNCT dti-1356 2 25 , , PUNCT dti-1356 2 26 and and CCONJ dti-1356 2 27 related related ADJ dti-1356 2 28 receptors receptor NOUN dti-1356 2 29 in in ADP dti-1356 2 30 patients patient NOUN dti-1356 2 31 with with ADP dti-1356 2 32 gastrointestinal gastrointestinal ADJ dti-1356 2 33 dysfunction dysfunction NOUN dti-1356 2 34 or or CCONJ dti-1356 2 35 diabetes diabetes NOUN dti-1356 2 36 mellitus mellitus PROPN dti-1356 2 37 bodil bodil PROPN dti-1356 2 38 roth1 roth1 PROPN dti-1356 2 39 , , PUNCT dti-1356 2 40 kerstin kerstin PROPN dti-1356 2 41 berntorp2 berntorp2 PROPN dti-1356 2 42 and and CCONJ dti-1356 2 43 bodil bodil PROPN dti-1356 2 44 ohlsson1 ohlsson1 PROPN dti-1356 2 45 department department NOUN dti-1356 2 46 of of ADP dti-1356 2 47 clinical clinical ADJ dti-1356 2 48 sciences science NOUN dti-1356 2 49 , , PUNCT dti-1356 2 50 1section 1section NUM dti-1356 2 51 of of ADP dti-1356 2 52 internal internal ADJ dti-1356 2 53 medicine medicine NOUN dti-1356 2 54 and and CCONJ dti-1356 2 55 2section 2section NUM dti-1356 2 56 of of ADP dti-1356 2 57 endocrinology endocrinology NOUN dti-1356 2 58 , , PUNCT dti-1356 2 59 skåne skåne PROPN dti-1356 2 60 university university PROPN dti-1356 2 61 hospital hospital NOUN dti-1356 2 62 , , PUNCT dti-1356 2 63 malmö malmö PROPN dti-1356 2 64 , , PUNCT dti-1356 2 65 sweden sweden PROPN dti-1356 2 66 . . PROPN dti-1356 3 1 lund lund PROPN dti-1356 3 2 university university PROPN dti-1356 3 3 , , PUNCT dti-1356 3 4 lund lund PROPN dti-1356 3 5 , , PUNCT dti-1356 3 6 sweden sweden PROPN dti-1356 3 7 . . PUNCT dti-1356 4 1 abstr abstr PROPN dti-1356 4 2 act act PROPN dti-1356 4 3 : : PUNCT dti-1356 4 4 gonadotropin gonadotropin NOUN dti-1356 4 5 - - PUNCT dti-1356 4 6 releasing release VERB dti-1356 4 7 hormone hormone NOUN dti-1356 4 8 ( ( PUNCT dti-1356 4 9 gnrh gnrh NOUN dti-1356 4 10 ) ) PUNCT dti-1356 4 11 1 1 NUM dti-1356 4 12 and and CCONJ dti-1356 4 13 2 2 NUM dti-1356 4 14 and and CCONJ dti-1356 4 15 luteinizing luteinize VERB dti-1356 4 16 hormone hormone NOUN dti-1356 4 17 ( ( PUNCT dti-1356 4 18 lh lh NOUN dti-1356 4 19 ) ) PUNCT dti-1356 4 20 receptors receptor NOUN dti-1356 4 21 have have AUX dti-1356 4 22 been be AUX dti-1356 4 23 described describe VERB dti-1356 4 24 in in ADP dti-1356 4 25 the the DET dti-1356 4 26 gastrointestinal gastrointestinal ADJ dti-1356 4 27 tract tract NOUN dti-1356 4 28 . . PUNCT dti-1356 5 1 we we PRON dti-1356 5 2 have have AUX dti-1356 5 3 previously previously ADV dti-1356 5 4 demonstrated demonstrate VERB dti-1356 5 5 antibodies antibody NOUN dti-1356 5 6 in in ADP dti-1356 5 7 serum serum NOUN dti-1356 5 8 against against ADP dti-1356 5 9 gnrh1 gnrh1 NOUN dti-1356 5 10 in in ADP dti-1356 5 11 patients patient NOUN dti-1356 5 12 with with ADP dti-1356 5 13 gastrointestinal gastrointestinal ADJ dti-1356 5 14 dysfunction dysfunction NOUN dti-1356 5 15 and and CCONJ dti-1356 5 16 diabetes diabetes NOUN dti-1356 5 17 mellitus mellitus NOUN dti-1356 5 18 , , PUNCT dti-1356 5 19 and and CCONJ dti-1356 5 20 antibodies antibodie VERB dti-1356 5 21 against against ADP dti-1356 5 22 gnrh gnrh NOUN dti-1356 5 23 receptor receptor NOUN dti-1356 5 24 , , PUNCT dti-1356 5 25 lh lh PROPN dti-1356 5 26 , , PUNCT dti-1356 5 27 and and CCONJ dti-1356 5 28 lh lh PROPN dti-1356 5 29 receptor receptor NOUN dti-1356 5 30 in in ADP dti-1356 5 31 patients patient NOUN dti-1356 5 32 with with ADP dti-1356 5 33 infertility infertility NOUN dti-1356 5 34 . . PUNCT dti-1356 6 1 the the DET dti-1356 6 2 aim aim NOUN dti-1356 6 3 of of ADP dti-1356 6 4 this this DET dti-1356 6 5 study study NOUN dti-1356 6 6 was be AUX dti-1356 6 7 to to PART dti-1356 6 8 search search VERB dti-1356 6 9 for for ADP dti-1356 6 10 the the DET dti-1356 6 11 expression expression NOUN dti-1356 6 12 of of ADP dti-1356 6 13 serum serum NOUN dti-1356 6 14 antibodies antibody NOUN dti-1356 6 15 against against ADP dti-1356 6 16 gnrh1 gnrh1 NOUN dti-1356 6 17 with with ADP dti-1356 6 18 an an DET dti-1356 6 19 improved improve VERB dti-1356 6 20 enzyme enzyme NOUN dti-1356 6 21 - - PUNCT dti-1356 6 22 linked link VERB dti-1356 6 23 immune immune ADJ dti-1356 6 24 sorbent sorbent NOUN dti-1356 6 25 assay assay NOUN dti-1356 6 26 ( ( PUNCT dti-1356 6 27 elisa elisa NOUN dti-1356 6 28 ) ) PUNCT dti-1356 6 29 , , PUNCT dti-1356 6 30 and and CCONJ dti-1356 6 31 antibodies antibodie VERB dti-1356 6 32 against against ADP dti-1356 6 33 progonadoliberin-2 progonadoliberin-2 NUM dti-1356 6 34 , , PUNCT dti-1356 6 35 gnrh2 gnrh2 NOUN dti-1356 6 36 , , PUNCT dti-1356 6 37 gnrh gnrh NOUN dti-1356 6 38 receptor receptor NOUN dti-1356 6 39 , , PUNCT dti-1356 6 40 lh lh PROPN dti-1356 6 41 , , PUNCT dti-1356 6 42 and and CCONJ dti-1356 6 43 lh lh PROPN dti-1356 6 44 receptor receptor NOUN dti-1356 6 45 with with ADP dti-1356 6 46 newly newly ADV dti-1356 6 47 developed develop VERB dti-1356 6 48 elisas elisa NOUN dti-1356 6 49 , , PUNCT dti-1356 6 50 in in ADP dti-1356 6 51 patients patient NOUN dti-1356 6 52 with with ADP dti-1356 6 53 gastrointestinal gastrointestinal ADJ dti-1356 6 54 dysfunction dysfunction NOUN dti-1356 6 55 or or CCONJ dti-1356 6 56 diabetes diabetes NOUN dti-1356 6 57 mellitus mellitus NOUN dti-1356 6 58 . . PUNCT dti-1356 7 1 healthy healthy ADJ dti-1356 7 2 blood blood NOUN dti-1356 7 3 donors donor NOUN dti-1356 7 4 served serve VERB dti-1356 7 5 as as ADP dti-1356 7 6 controls control NOUN dti-1356 7 7 . . PUNCT dti-1356 8 1 medical medical ADJ dti-1356 8 2 records record NOUN dti-1356 8 3 were be AUX dti-1356 8 4 scrutinized scrutinize VERB dti-1356 8 5 . . PUNCT dti-1356 9 1 our our PRON dti-1356 9 2 conclusion conclusion NOUN dti-1356 9 3 was be AUX dti-1356 9 4 that that SCONJ dti-1356 9 5 igm igm PROPN dti-1356 9 6 antibodies antibody NOUN dti-1356 9 7 against against ADP dti-1356 9 8 gnrh1 gnrh1 PROPN dti-1356 9 9 , , PUNCT dti-1356 9 10 progonadoliberin-2 progonadoliberin-2 NUM dti-1356 9 11 , , PUNCT dti-1356 9 12 and/or and/or CCONJ dti-1356 9 13 gnrh gnrh NOUN dti-1356 9 14 receptors receptor NOUN dti-1356 9 15 were be AUX dti-1356 9 16 more more ADV dti-1356 9 17 prevalent prevalent ADJ dti-1356 9 18 in in ADP dti-1356 9 19 patients patient NOUN dti-1356 9 20 with with ADP dti-1356 9 21 functional functional ADJ dti-1356 9 22 gastrointestinal gastrointestinal ADJ dti-1356 9 23 disorders disorder NOUN dti-1356 9 24 , , PUNCT dti-1356 9 25 gastrointestinal gastrointestinal ADJ dti-1356 9 26 dysmotility dysmotility NOUN dti-1356 9 27 , , PUNCT dti-1356 9 28 and/or and/or CCONJ dti-1356 9 29 diabetes diabete VERB dti-1356 9 30 mellitus mellitus NOUN dti-1356 9 31 , , PUNCT dti-1356 9 32 whereas whereas SCONJ dti-1356 9 33 igg igg PROPN dti-1356 9 34 antibodies antibodie VERB dti-1356 9 35 against against ADP dti-1356 9 36 these these DET dti-1356 9 37 peptides peptide NOUN dti-1356 9 38 , , PUNCT dti-1356 9 39 and and CCONJ dti-1356 9 40 lhand lhand VERB dti-1356 9 41 lh lh PROPN dti-1356 9 42 receptor receptor NOUN dti-1356 9 43 antibodies antibodie VERB dti-1356 9 44 , , PUNCT dti-1356 9 45 were be AUX dti-1356 9 46 expressed express VERB dti-1356 9 47 in in ADP dti-1356 9 48 the the DET dti-1356 9 49 same same ADJ dti-1356 9 50 magnitude magnitude NOUN dti-1356 9 51 as as ADP dti-1356 9 52 in in ADP dti-1356 9 53 controls control NOUN dti-1356 9 54 . . PUNCT dti-1356 10 1 key key ADJ dti-1356 10 2 words word NOUN dti-1356 10 3 : : PUNCT dti-1356 10 4 antibodies antibodie VERB dti-1356 10 5 , , PUNCT dti-1356 10 6 diabetes diabetes NOUN dti-1356 10 7 mellitus mellitus NOUN dti-1356 10 8 , , PUNCT dti-1356 10 9 gastrointestinal gastrointestinal ADJ dti-1356 10 10 dysmotility dysmotility NOUN dti-1356 10 11 , , PUNCT dti-1356 10 12 gonadotropin gonadotropin NOUN dti-1356 10 13 - - PUNCT dti-1356 10 14 releasing release VERB dti-1356 10 15 hormone hormone NOUN dti-1356 10 16 ( ( PUNCT dti-1356 10 17 gnrh gnrh NOUN dti-1356 10 18 ) ) PUNCT dti-1356 10 19 , , PUNCT dti-1356 10 20 luteinizing luteinize VERB dti-1356 10 21 hormone hormone NOUN dti-1356 10 22 ( ( PUNCT dti-1356 10 23 lh lh PROPN dti-1356 10 24 ) ) PUNCT dti-1356 10 25 , , PUNCT dti-1356 10 26 progonadoliberin-2 progonadoliberin-2 NUM dti-1356 10 27 citation citation NOUN dti-1356 10 28 : : PUNCT dti-1356 10 29 roth roth PROPN dti-1356 10 30 et et PROPN dti-1356 10 31 al al PROPN dti-1356 10 32 . . PUNCT dti-1356 11 1 the the DET dti-1356 11 2 expression expression NOUN dti-1356 11 3 of of ADP dti-1356 11 4 serum serum NOUN dti-1356 11 5 antibodies antibody NOUN dti-1356 11 6 against against ADP dti-1356 11 7 gonadotropin gonadotropin NOUN dti-1356 11 8 - - PUNCT dti-1356 11 9 releasing release VERB dti-1356 11 10 hormone hormone NOUN dti-1356 11 11 ( ( PUNCT dti-1356 11 12 gnrh1 gnrh1 NOUN dti-1356 11 13 ) ) PUNCT dti-1356 11 14 , , PUNCT dti-1356 11 15 progonadoliberin-2 progonadoliberin-2 NUM dti-1356 11 16 , , PUNCT dti-1356 11 17 luteinizing luteinize VERB dti-1356 11 18 hormone hormone NOUN dti-1356 11 19 ( ( PUNCT dti-1356 11 20 lh lh PROPN dti-1356 11 21 ) ) PUNCT dti-1356 11 22 , , PUNCT dti-1356 11 23 and and CCONJ dti-1356 11 24 related related ADJ dti-1356 11 25 receptors receptor NOUN dti-1356 11 26 in in ADP dti-1356 11 27 patients patient NOUN dti-1356 11 28 with with ADP dti-1356 11 29 gastrointestinal gastrointestinal ADJ dti-1356 11 30 dysfunction dysfunction NOUN dti-1356 11 31 or or CCONJ dti-1356 11 32 diabetes diabetes NOUN dti-1356 11 33 mellitus mellitus NOUN dti-1356 11 34 . . PUNCT dti-1356 12 1 drug drug NOUN dti-1356 12 2 target target NOUN dti-1356 12 3 insights insight VERB dti-1356 12 4 2014:8 2014:8 NUM dti-1356 12 5 45–50 45–50 NUM dti-1356 12 6 doi:10.4137 doi:10.4137 NOUN dti-1356 12 7 / / SYM dti-1356 12 8 dti.s19352 dti.s19352 NOUN dti-1356 12 9 . . PUNCT dti-1356 13 1 received receive VERB dti-1356 13 2 : : PUNCT dti-1356 13 3 august august PROPN dti-1356 13 4 13 13 NUM dti-1356 13 5 , , PUNCT dti-1356 13 6 2014 2014 NUM dti-1356 13 7 . . PUNCT dti-1356 14 1 resubmitted resubmitte VERB dti-1356 14 2 : : PUNCT dti-1356 14 3 september september PROPN dti-1356 14 4 19 19 NUM dti-1356 14 5 , , PUNCT dti-1356 14 6 2014 2014 NUM dti-1356 14 7 . . PUNCT dti-1356 15 1 accepted accept VERB dti-1356 15 2 for for ADP dti-1356 15 3 publication publication NOUN dti-1356 15 4 : : PUNCT dti-1356 15 5 october october PROPN dti-1356 15 6 8 8 NUM dti-1356 15 7 , , PUNCT dti-1356 15 8 2014 2014 NUM dti-1356 15 9 . . PUNCT dti-1356 16 1 academic academic ADJ dti-1356 16 2 editor editor NOUN dti-1356 16 3 : : PUNCT dti-1356 16 4 anuj anuj PROPN dti-1356 16 5 chauhan chauhan PROPN dti-1356 16 6 , , PUNCT dti-1356 16 7 editor editor NOUN dti-1356 16 8 in in ADP dti-1356 16 9 chief chief ADJ dti-1356 16 10 type type NOUN dti-1356 16 11 : : PUNCT dti-1356 16 12 original original ADJ dti-1356 16 13 research research NOUN dti-1356 16 14 funding funding NOUN dti-1356 16 15 : : PUNCT dti-1356 16 16 grants grant NOUN dti-1356 16 17 from from ADP dti-1356 16 18 the the DET dti-1356 16 19 bengt bengt PROPN dti-1356 16 20 ihre ihre PROPN dti-1356 16 21 foundation foundation PROPN dti-1356 16 22 , , PUNCT dti-1356 16 23 the the DET dti-1356 16 24 king king NOUN dti-1356 16 25 gustaf gustaf PROPN dti-1356 16 26 v v ADP dti-1356 16 27 : : PUNCT dti-1356 16 28 s s X dti-1356 16 29 and and CCONJ dti-1356 16 30 queen queen PROPN dti-1356 16 31 victoria victoria PROPN dti-1356 16 32 free free PROPN dti-1356 16 33 mason mason PROPN dti-1356 16 34 ’s ’s PART dti-1356 16 35 foundation foundation PROPN dti-1356 16 36 , , PUNCT dti-1356 16 37 albert albert PROPN dti-1356 16 38 påhlsson påhlsson PROPN dti-1356 16 39 foundation foundation PROPN dti-1356 16 40 , , PUNCT dti-1356 16 41 and and CCONJ dti-1356 16 42 the the DET dti-1356 16 43 development development NOUN dti-1356 16 44 foundation foundation PROPN dti-1356 16 45 of of ADP dti-1356 16 46 region region NOUN dti-1356 16 47 skåne skåne PROPN dti-1356 16 48 sponsored sponsor VERB dti-1356 16 49 this this DET dti-1356 16 50 study study NOUN dti-1356 16 51 . . PUNCT dti-1356 17 1 the the DET dti-1356 17 2 authors author NOUN dti-1356 17 3 confirm confirm VERB dti-1356 17 4 that that SCONJ dti-1356 17 5 the the DET dti-1356 17 6 funder funder NOUN dti-1356 17 7 had have VERB dti-1356 17 8 no no DET dti-1356 17 9 influence influence NOUN dti-1356 17 10 over over ADP dti-1356 17 11 the the DET dti-1356 17 12 study study NOUN dti-1356 17 13 design design NOUN dti-1356 17 14 , , PUNCT dti-1356 17 15 content content NOUN dti-1356 17 16 of of ADP dti-1356 17 17 the the DET dti-1356 17 18 article article NOUN dti-1356 17 19 , , PUNCT dti-1356 17 20 or or CCONJ dti-1356 17 21 selection selection NOUN dti-1356 17 22 of of ADP dti-1356 17 23 this this DET dti-1356 17 24 journal journal NOUN dti-1356 17 25 . . PUNCT dti-1356 18 1 competing compete VERB dti-1356 18 2 interests interest NOUN dti-1356 18 3 : : PUNCT dti-1356 18 4 authors author NOUN dti-1356 18 5 disclose disclose VERB dti-1356 18 6 no no DET dti-1356 18 7 potential potential ADJ dti-1356 18 8 conflicts conflict NOUN dti-1356 18 9 of of ADP dti-1356 18 10 interest interest NOUN dti-1356 18 11 . . PUNCT dti-1356 19 1 copyright copyright NOUN dti-1356 19 2 : : PUNCT dti-1356 19 3 © © PROPN dti-1356 19 4 the the DET dti-1356 19 5 authors author NOUN dti-1356 19 6 , , PUNCT dti-1356 19 7 publisher publisher NOUN dti-1356 19 8 and and CCONJ dti-1356 19 9 licensee licensee NOUN dti-1356 19 10 libertas liberta NOUN dti-1356 19 11 academica academica PROPN dti-1356 19 12 limited limit VERB dti-1356 19 13 . . PUNCT dti-1356 20 1 this this PRON dti-1356 20 2 is be AUX dti-1356 20 3 an an DET dti-1356 20 4 open open ADJ dti-1356 20 5 - - PUNCT dti-1356 20 6 access access NOUN dti-1356 20 7 article article NOUN dti-1356 20 8 distributed distribute VERB dti-1356 20 9 under under ADP dti-1356 20 10 the the DET dti-1356 20 11 terms term NOUN dti-1356 20 12 of of ADP dti-1356 20 13 the the DET dti-1356 20 14 creative creative ADJ dti-1356 20 15 commons common NOUN dti-1356 20 16 cc cc NOUN dti-1356 20 17 - - PUNCT dti-1356 20 18 by by ADP dti-1356 20 19 - - PUNCT dti-1356 20 20 nc nc PROPN dti-1356 20 21 3.0 3.0 NUM dti-1356 20 22 license license NOUN dti-1356 20 23 . . PUNCT dti-1356 21 1 correspondence correspondence NOUN dti-1356 21 2 : : PUNCT dti-1356 21 3 bodil.ohlsson@med.lu.se bodil.ohlsson@med.lu.se NOUN dti-1356 21 4 paper paper PROPN dti-1356 21 5 subject subject NOUN dti-1356 21 6 to to ADP dti-1356 21 7 independent independent ADJ dti-1356 21 8 expert expert NOUN dti-1356 21 9 blind blind ADJ dti-1356 21 10 peer peer NOUN dti-1356 21 11 review review NOUN dti-1356 21 12 by by ADP dti-1356 21 13 minimum minimum NOUN dti-1356 21 14 of of ADP dti-1356 21 15 two two NUM dti-1356 21 16 reviewers reviewer NOUN dti-1356 21 17 . . PUNCT dti-1356 22 1 all all DET dti-1356 22 2 editorial editorial ADJ dti-1356 22 3 decisions decision NOUN dti-1356 22 4 made make VERB dti-1356 22 5 by by ADP dti-1356 22 6 independent independent ADJ dti-1356 22 7 academic academic ADJ dti-1356 22 8 editor editor NOUN dti-1356 22 9 . . PUNCT dti-1356 23 1 upon upon SCONJ dti-1356 23 2 submission submission NOUN dti-1356 23 3 manuscript manuscript NOUN dti-1356 23 4 was be AUX dti-1356 23 5 subject subject ADJ dti-1356 23 6 to to ADP dti-1356 23 7 anti anti ADJ dti-1356 23 8 - - NOUN dti-1356 23 9 plagiarism plagiarism ADJ dti-1356 23 10 scanning scanning NOUN dti-1356 23 11 . . PUNCT dti-1356 24 1 prior prior ADV dti-1356 24 2 to to ADP dti-1356 24 3 publication publication NOUN dti-1356 24 4 all all DET dti-1356 24 5 authors author NOUN dti-1356 24 6 have have AUX dti-1356 24 7 given give VERB dti-1356 24 8 signed sign VERB dti-1356 24 9 confirmation confirmation NOUN dti-1356 24 10 of of ADP dti-1356 24 11 agreement agreement NOUN dti-1356 24 12 to to ADP dti-1356 24 13 article article NOUN dti-1356 24 14 publication publication NOUN dti-1356 24 15 and and CCONJ dti-1356 24 16 compliance compliance NOUN dti-1356 24 17 with with ADP dti-1356 24 18 all all DET dti-1356 24 19 applicable applicable ADJ dti-1356 24 20 ethical ethical ADJ dti-1356 24 21 and and CCONJ dti-1356 24 22 legal legal ADJ dti-1356 24 23 requirements requirement NOUN dti-1356 24 24 , , PUNCT dti-1356 24 25 including include VERB dti-1356 24 26 the the DET dti-1356 24 27 accuracy accuracy NOUN dti-1356 24 28 of of ADP dti-1356 24 29 author author NOUN dti-1356 24 30 and and CCONJ dti-1356 24 31 contributor contributor NOUN dti-1356 24 32 information information NOUN dti-1356 24 33 , , PUNCT dti-1356 24 34 disclosure disclosure NOUN dti-1356 24 35 of of ADP dti-1356 24 36 competing compete VERB dti-1356 24 37 interests interest NOUN dti-1356 24 38 and and CCONJ dti-1356 24 39 funding funding NOUN dti-1356 24 40 sources source NOUN dti-1356 24 41 , , PUNCT dti-1356 24 42 compliance compliance NOUN dti-1356 24 43 with with ADP dti-1356 24 44 ethical ethical ADJ dti-1356 24 45 requirements requirement NOUN dti-1356 24 46 relating relate VERB dti-1356 24 47 to to ADP dti-1356 24 48 human human ADJ dti-1356 24 49 and and CCONJ dti-1356 24 50 animal animal NOUN dti-1356 24 51 study study NOUN dti-1356 24 52 participants participant NOUN dti-1356 24 53 , , PUNCT dti-1356 24 54 and and CCONJ dti-1356 24 55 compliance compliance NOUN dti-1356 24 56 with with ADP dti-1356 24 57 any any DET dti-1356 24 58 copyright copyright NOUN dti-1356 24 59 requirements requirement NOUN dti-1356 24 60 of of ADP dti-1356 24 61 third third ADJ dti-1356 24 62 parties party NOUN dti-1356 24 63 . . PUNCT dti-1356 25 1 this this DET dti-1356 25 2 journal journal NOUN dti-1356 25 3 is be AUX dti-1356 25 4 a a DET dti-1356 25 5 member member NOUN dti-1356 25 6 of of ADP dti-1356 25 7 the the DET dti-1356 25 8 committee committee NOUN dti-1356 25 9 on on ADP dti-1356 25 10 publication publication NOUN dti-1356 25 11 ethics ethic NOUN dti-1356 25 12 ( ( PUNCT dti-1356 25 13 cope cope PROPN dti-1356 25 14 ) ) PUNCT dti-1356 25 15 . . PUNCT dti-1356 26 1 introduction introduction NOUN dti-1356 26 2 irritable irritable ADJ dti-1356 26 3 bowel bowel NOUN dti-1356 26 4 syndrome syndrome NOUN dti-1356 26 5 ( ( PUNCT dti-1356 26 6 ibs ibs PROPN dti-1356 26 7 ) ) PUNCT dti-1356 26 8 is be AUX dti-1356 26 9 a a DET dti-1356 26 10 common common ADJ dti-1356 26 11 gastrointestinal gastrointestinal ADJ dti-1356 26 12 disorder disorder NOUN dti-1356 26 13 , , PUNCT dti-1356 26 14 occurring occur VERB dti-1356 26 15 in in ADP dti-1356 26 16 10–15 10–15 NUM dti-1356 26 17 % % NOUN dti-1356 26 18 of of ADP dti-1356 26 19 the the DET dti-1356 26 20 population population NOUN dti-1356 26 21 . . PUNCT dti-1356 27 1 the the DET dti-1356 27 2 etiology etiology NOUN dti-1356 27 3 is be AUX dti-1356 27 4 unknown unknown ADJ dti-1356 27 5 , , PUNCT dti-1356 27 6 and and CCONJ dti-1356 27 7 no no DET dti-1356 27 8 organic organic ADJ dti-1356 27 9 , , PUNCT dti-1356 27 10 pathognomonic pathognomonic ADJ dti-1356 27 11 changes change NOUN dti-1356 27 12 have have AUX dti-1356 27 13 been be AUX dti-1356 27 14 established establish VERB dti-1356 27 15 so so ADV dti-1356 27 16 far.1 far.1 PROPN dti-1356 27 17 relatively relatively ADV dti-1356 27 18 severe severe ADJ dti-1356 27 19 gastrointestinal gastrointestinal ADJ dti-1356 27 20 dysmotility dysmotility NOUN dti-1356 27 21 is be AUX dti-1356 27 22 often often ADV dti-1356 27 23 found find VERB dti-1356 27 24 as as ADP dti-1356 27 25 a a DET dti-1356 27 26 complication complication NOUN dti-1356 27 27 in in ADP dti-1356 27 28 diabetes diabetes NOUN dti-1356 27 29 mellitus mellitus NOUN dti-1356 27 30 and and CCONJ dti-1356 27 31 rheumatologic rheumatologic NOUN dti-1356 27 32 and and CCONJ dti-1356 27 33 neurologic neurologic ADJ dti-1356 27 34 diseases.2,3 diseases.2,3 NOUN dti-1356 27 35 as as SCONJ dti-1356 27 36 women woman NOUN dti-1356 27 37 are be AUX dti-1356 27 38 affected affect VERB dti-1356 27 39 by by ADP dti-1356 27 40 these these DET dti-1356 27 41 disorders disorder NOUN dti-1356 27 42 more more ADV dti-1356 27 43 often often ADV dti-1356 27 44 than than ADP dti-1356 27 45 men man NOUN dti-1356 27 46 , , PUNCT dti-1356 27 47 hormonal hormonal ADJ dti-1356 27 48 influences influence NOUN dti-1356 27 49 on on ADP dti-1356 27 50 the the DET dti-1356 27 51 gastrointestinal gastrointestinal ADJ dti-1356 27 52 tract tract NOUN dti-1356 27 53 have have AUX dti-1356 27 54 been be AUX dti-1356 27 55 assumed.4 assumed.4 ADJ dti-1356 27 56 we we PRON dti-1356 27 57 have have AUX dti-1356 27 58 recently recently ADV dti-1356 27 59 described describe VERB dti-1356 27 60 the the DET dti-1356 27 61 expression expression NOUN dti-1356 27 62 of of ADP dti-1356 27 63 gonadotropinreleasing gonadotropinrelease VERB dti-1356 27 64 hormone hormone NOUN dti-1356 27 65 ( ( PUNCT dti-1356 27 66 gnrh gnrh NOUN dti-1356 27 67 , , PUNCT dti-1356 27 68 1 1 NUM dti-1356 27 69 and and CCONJ dti-1356 27 70 2 2 NUM dti-1356 27 71 ) ) PUNCT dti-1356 27 72 and and CCONJ dti-1356 27 73 receptors receptor NOUN dti-1356 27 74 for for ADP dti-1356 27 75 luteinizing luteinize VERB dti-1356 27 76 hormone hormone NOUN dti-1356 27 77 ( ( PUNCT dti-1356 27 78 lh lh PROPN dti-1356 27 79 ) ) PUNCT dti-1356 27 80 in in ADP dti-1356 27 81 the the DET dti-1356 27 82 human human ADJ dti-1356 27 83 enteric enteric ADJ dti-1356 27 84 nervous nervous ADJ dti-1356 27 85 system system NOUN dti-1356 27 86 ( ( PUNCT dti-1356 27 87 ens).5–8 ens).5–8 PROPN dti-1356 27 88 the the DET dti-1356 27 89 effects effect NOUN dti-1356 27 90 of of ADP dti-1356 27 91 these these DET dti-1356 27 92 peptides peptide NOUN dti-1356 27 93 are be AUX dti-1356 27 94 not not PART dti-1356 27 95 known know VERB dti-1356 27 96 , , PUNCT dti-1356 27 97 but but CCONJ dti-1356 27 98 a a DET dti-1356 27 99 few few ADJ dti-1356 27 100 studies study NOUN dti-1356 27 101 have have AUX dti-1356 27 102 described describe VERB dti-1356 27 103 an an DET dti-1356 27 104 influence influence NOUN dti-1356 27 105 by by ADP dti-1356 27 106 gnrh gnrh NOUN dti-1356 27 107 and and CCONJ dti-1356 27 108 lh lh PROPN dti-1356 27 109 on on ADP dti-1356 27 110 the the DET dti-1356 27 111 migrating migrating NOUN dti-1356 27 112 motor motor NOUN dti-1356 27 113 complex complex NOUN dti-1356 28 1 ( ( PUNCT dti-1356 28 2 mmc).9–11 mmc).9–11 PROPN dti-1356 28 3 we we PRON dti-1356 28 4 have have AUX dti-1356 28 5 developed develop VERB dti-1356 28 6 an an DET dti-1356 28 7 in in ADP dti-1356 28 8 - - PUNCT dti-1356 28 9 house house NOUN dti-1356 28 10 enzyme enzyme NOUN dti-1356 28 11 - - PUNCT dti-1356 28 12 linked link VERB dti-1356 28 13 immune immune ADJ dti-1356 28 14 sorbent sorbent NOUN dti-1356 28 15 assay assay NOUN dti-1356 28 16 ( ( PUNCT dti-1356 28 17 elisa elisa NOUN dti-1356 28 18 ) ) PUNCT dti-1356 28 19 to to PART dti-1356 28 20 describe describe VERB dti-1356 28 21 the the DET dti-1356 28 22 presence presence NOUN dti-1356 28 23 of of ADP dti-1356 28 24 serum serum NOUN dti-1356 28 25 antibodies antibody NOUN dti-1356 28 26 against against ADP dti-1356 28 27 gnrh1 gnrh1 NOUN dti-1356 28 28 in in ADP dti-1356 28 29 patients patient NOUN dti-1356 28 30 with with ADP dti-1356 28 31 ibs ibs PROPN dti-1356 28 32 , , PUNCT dti-1356 28 33 dysmotility dysmotility NOUN dti-1356 28 34 , , PUNCT dti-1356 28 35 and and CCONJ dti-1356 28 36 diabetes diabetes NOUN dti-1356 28 37 mellitus mellitus NOUN dti-1356 28 38 , , PUNCT dti-1356 28 39 but but CCONJ dti-1356 28 40 not not PART dti-1356 28 41 in in ADP dti-1356 28 42 inflammatory inflammatory ADJ dti-1356 28 43 bowel bowel NOUN dti-1356 28 44 disease disease NOUN dti-1356 28 45 ( ( PUNCT dti-1356 28 46 ibd ibd PROPN dti-1356 28 47 ) ) PUNCT dti-1356 28 48 or or CCONJ dti-1356 28 49 celiac celiac NOUN dti-1356 28 50 disease,12,13 disease,12,13 NOUN dti-1356 28 51 as as ADV dti-1356 28 52 well well ADV dti-1356 28 53 as as ADP dti-1356 28 54 in in ADP dti-1356 28 55 patients patient NOUN dti-1356 28 56 with with ADP dti-1356 28 57 functional functional ADJ dti-1356 28 58 gastrointestinal gastrointestinal ADJ dti-1356 28 59 complaints complaint NOUN dti-1356 28 60 in in ADP dti-1356 28 61 association association NOUN dti-1356 28 62 with with ADP dti-1356 28 63 primary primary ADJ dti-1356 28 64 sjögren sjögren PROPN dti-1356 28 65 ’s ’s PART dti-1356 28 66 syndrome.3,14 syndrome.3,14 NOUN dti-1356 28 67 the the DET dti-1356 28 68 pathophysiological pathophysiological ADJ dti-1356 28 69 role role NOUN dti-1356 28 70 of of ADP dti-1356 28 71 these these DET dti-1356 28 72 antibodies antibody NOUN dti-1356 28 73 is be AUX dti-1356 28 74 unknown unknown ADJ dti-1356 28 75 . . PUNCT dti-1356 29 1 the the DET dti-1356 29 2 original original ADJ dti-1356 29 3 http://www.la-press.com/drug-target-insights-journal-j23 http://www.la-press.com/drug-target-insights-journal-j23 PROPN dti-1356 29 4 http://www.la-press.com http://www.la-press.com X dti-1356 29 5 http://www.la-press.com http://www.la-press.com X dti-1356 29 6 http://www.la-press.com/drug-target-insights-journal-j23 http://www.la-press.com/drug-target-insights-journal-j23 PROPN dti-1356 30 1 http://dx.doi.org/10.4137/dti.s19352 http://dx.doi.org/10.4137/dti.s19352 X dti-1356 30 2 http://creativecommons.org/licenses/by-nc/3.0/ http://creativecommons.org/licenses/by-nc/3.0/ PRON dti-1356 30 3 http://creativecommons.org/licenses/by-nc/3.0/ http://creativecommons.org/licenses/by-nc/3.0/ NOUN dti-1356 31 1 mailto:bodil.ohlsson@med.lu.se mailto:bodil.ohlsson@med.lu.se PROPN dti-1356 31 2 roth roth PROPN dti-1356 31 3 et et PROPN dti-1356 31 4 al al PROPN dti-1356 31 5 46 46 NUM dti-1356 31 6 drug drug NOUN dti-1356 31 7 target target NOUN dti-1356 31 8 insights insight NOUN dti-1356 31 9 2014:8 2014:8 NUM dti-1356 31 10 elisa elisa NOUN dti-1356 31 11 was be AUX dti-1356 31 12 associated associate VERB dti-1356 31 13 with with ADP dti-1356 31 14 a a DET dti-1356 31 15 high high ADJ dti-1356 31 16 degree degree NOUN dti-1356 31 17 of of ADP dti-1356 31 18 background background NOUN dti-1356 31 19 signaling.3,5,6,12,13 signaling.3,5,6,12,13 NOUN dti-1356 31 20 the the DET dti-1356 31 21 method method NOUN dti-1356 31 22 has have AUX dti-1356 31 23 now now ADV dti-1356 31 24 been be AUX dti-1356 31 25 further far ADV dti-1356 31 26 improved improve VERB dti-1356 31 27 and and CCONJ dti-1356 31 28 we we PRON dti-1356 31 29 have have AUX dti-1356 31 30 also also ADV dti-1356 31 31 developed develop VERB dti-1356 31 32 elisas elisa NOUN dti-1356 31 33 for for ADP dti-1356 31 34 the the DET dti-1356 31 35 gnrh gnrh NOUN dti-1356 31 36 receptor receptor NOUN dti-1356 31 37 , , PUNCT dti-1356 31 38 lh lh PROPN dti-1356 31 39 , , PUNCT dti-1356 31 40 and and CCONJ dti-1356 31 41 lh lh PROPN dti-1356 31 42 receptor.14–16 receptor.14–16 NOUN dti-1356 31 43 furthermore furthermore ADV dti-1356 31 44 , , PUNCT dti-1356 31 45 we we PRON dti-1356 31 46 have have AUX dti-1356 31 47 developed develop VERB dti-1356 31 48 an an DET dti-1356 31 49 elisa elisa NOUN dti-1356 31 50 for for ADP dti-1356 31 51 measurement measurement NOUN dti-1356 31 52 of of ADP dti-1356 31 53 antibodies antibody NOUN dti-1356 31 54 against against ADP dti-1356 31 55 gnrh2 gnrh2 NOUN dti-1356 31 56 and and CCONJ dti-1356 31 57 its its PRON dti-1356 31 58 precursor precursor NOUN dti-1356 31 59 , , PUNCT dti-1356 31 60 progonadoliberin-2 progonadoliberin-2 NUM dti-1356 31 61 , , PUNCT dti-1356 31 62 as as SCONJ dti-1356 31 63 these these DET dti-1356 31 64 peptides peptide NOUN dti-1356 31 65 are be AUX dti-1356 31 66 abundantly abundantly ADV dti-1356 31 67 expressed express VERB dti-1356 31 68 in in ADP dti-1356 31 69 the the DET dti-1356 31 70 ens,8,17 ens,8,17 NOUN dti-1356 31 71 and and CCONJ dti-1356 31 72 could could AUX dti-1356 31 73 hypothetically hypothetically ADV dti-1356 31 74 be be AUX dti-1356 31 75 more more ADV dti-1356 31 76 important important ADJ dti-1356 31 77 for for ADP dti-1356 31 78 gastrointestinal gastrointestinal ADJ dti-1356 31 79 function function NOUN dti-1356 31 80 than than ADP dti-1356 31 81 gnrh1 gnrh1 PROPN dti-1356 31 82 . . PUNCT dti-1356 32 1 the the DET dti-1356 32 2 aim aim NOUN dti-1356 32 3 of of ADP dti-1356 32 4 the the DET dti-1356 32 5 present present ADJ dti-1356 32 6 study study NOUN dti-1356 32 7 was be AUX dti-1356 32 8 to to PART dti-1356 32 9 search search VERB dti-1356 32 10 for for ADP dti-1356 32 11 the the DET dti-1356 32 12 expression expression NOUN dti-1356 32 13 of of ADP dti-1356 32 14 antibodies antibody NOUN dti-1356 32 15 against against ADP dti-1356 32 16 gnrh1 gnrh1 PROPN dti-1356 32 17 , , PUNCT dti-1356 32 18 progonadoliberin-2 progonadoliberin-2 NUM dti-1356 32 19 , , PUNCT dti-1356 32 20 gnrh2 gnrh2 NOUN dti-1356 32 21 , , PUNCT dti-1356 32 22 gnrh gnrh NOUN dti-1356 32 23 receptor receptor NOUN dti-1356 32 24 , , PUNCT dti-1356 32 25 lh lh PROPN dti-1356 32 26 , , PUNCT dti-1356 32 27 and and CCONJ dti-1356 32 28 lh lh PROPN dti-1356 32 29 receptor receptor NOUN dti-1356 32 30 with with ADP dti-1356 32 31 new new ADJ dti-1356 32 32 , , PUNCT dti-1356 32 33 sensitive sensitive ADJ dti-1356 32 34 elisas elisas NOUN dti-1356 32 35 , , PUNCT dti-1356 32 36 in in ADP dti-1356 32 37 a a DET dti-1356 32 38 population population NOUN dti-1356 32 39 of of ADP dti-1356 32 40 patients patient NOUN dti-1356 32 41 with with ADP dti-1356 32 42 symptoms symptom NOUN dti-1356 32 43 and and CCONJ dti-1356 32 44 signs sign NOUN dti-1356 32 45 of of ADP dti-1356 32 46 functional functional ADJ dti-1356 32 47 gastrointestinal gastrointestinal ADJ dti-1356 32 48 disorders disorder NOUN dti-1356 32 49 or or CCONJ dti-1356 32 50 gastrointestinal gastrointestinal ADJ dti-1356 32 51 dysmotility dysmotility NOUN dti-1356 32 52 , , PUNCT dti-1356 32 53 and/or and/or CCONJ dti-1356 32 54 diabetes diabete VERB dti-1356 32 55 mellitus mellitus NOUN dti-1356 32 56 , , PUNCT dti-1356 32 57 and and CCONJ dti-1356 32 58 compare compare VERB dti-1356 32 59 these these PRON dti-1356 32 60 to to ADP dti-1356 32 61 healthy healthy ADJ dti-1356 32 62 blood blood NOUN dti-1356 32 63 donors donor NOUN dti-1356 32 64 , , PUNCT dti-1356 32 65 to to PART dti-1356 32 66 confirm confirm VERB dti-1356 32 67 the the DET dti-1356 32 68 presence presence NOUN dti-1356 32 69 of of ADP dti-1356 32 70 autoantibodies autoantibody NOUN dti-1356 32 71 in in ADP dti-1356 32 72 these these DET dti-1356 32 73 patients patient NOUN dti-1356 32 74 . . PUNCT dti-1356 33 1 materials material NOUN dti-1356 33 2 and and CCONJ dti-1356 33 3 methods method NOUN dti-1356 33 4 the the DET dti-1356 33 5 study study NOUN dti-1356 33 6 was be AUX dti-1356 33 7 performed perform VERB dti-1356 33 8 in in ADP dti-1356 33 9 accordance accordance NOUN dti-1356 33 10 with with ADP dti-1356 33 11 the the DET dti-1356 33 12 helsinki helsinki PROPN dti-1356 33 13 declaration declaration PROPN dti-1356 33 14 and and CCONJ dti-1356 33 15 after after ADP dti-1356 33 16 approval approval NOUN dti-1356 33 17 by by ADP dti-1356 33 18 the the DET dti-1356 33 19 ethics ethic NOUN dti-1356 33 20 review review PROPN dti-1356 33 21 board board PROPN dti-1356 33 22 of of ADP dti-1356 33 23 lund lund PROPN dti-1356 33 24 university university PROPN dti-1356 33 25 . . PUNCT dti-1356 34 1 consecutive consecutive ADJ dti-1356 34 2 patients patient NOUN dti-1356 34 3 visiting visit VERB dti-1356 34 4 the the DET dti-1356 34 5 out out ADJ dti-1356 34 6 - - PUNCT dti-1356 34 7 patient patient NOUN dti-1356 34 8 clinic clinic NOUN dti-1356 34 9 of of ADP dti-1356 34 10 the the DET dti-1356 34 11 departments department NOUN dti-1356 34 12 of of ADP dti-1356 34 13 gastroenterology gastroenterology NOUN dti-1356 34 14 or or CCONJ dti-1356 34 15 endocrinology endocrinology NOUN dti-1356 34 16 , , PUNCT dti-1356 34 17 skåne skåne PROPN dti-1356 34 18 university university PROPN dti-1356 34 19 hospital hospital NOUN dti-1356 34 20 , , PUNCT dti-1356 34 21 malmö malmö PROPN dti-1356 34 22 , , PUNCT dti-1356 34 23 were be AUX dti-1356 34 24 included include VERB dti-1356 34 25 . . PUNCT dti-1356 35 1 all all DET dti-1356 35 2 patients patient NOUN dti-1356 35 3 and and CCONJ dti-1356 35 4 blood blood NOUN dti-1356 35 5 donors donor NOUN dti-1356 35 6 had have AUX dti-1356 35 7 given give VERB dti-1356 35 8 their their PRON dti-1356 35 9 written write VERB dti-1356 35 10 , , PUNCT dti-1356 35 11 informed informed ADJ dti-1356 35 12 consent consent NOUN dti-1356 35 13 to to PART dti-1356 35 14 participate participate VERB dti-1356 35 15 in in ADP dti-1356 35 16 the the DET dti-1356 35 17 study study NOUN dti-1356 35 18 . . PUNCT dti-1356 36 1 patients patient NOUN dti-1356 36 2 suffering suffer VERB dti-1356 36 3 from from ADP dti-1356 36 4 ibs ib NOUN dti-1356 36 5 or or CCONJ dti-1356 36 6 gastrointestinal gastrointestinal ADJ dti-1356 36 7 dysmotility dysmotility NOUN dti-1356 36 8 . . PUNCT dti-1356 37 1 consecutive consecutive ADJ dti-1356 37 2 patients patient NOUN dti-1356 37 3 suffering suffer VERB dti-1356 37 4 from from ADP dti-1356 37 5 gastrointestinal gastrointestinal ADJ dti-1356 37 6 symptoms symptom NOUN dti-1356 37 7 suggesting suggest VERB dti-1356 37 8 ibs ibs PROPN dti-1356 37 9 or or CCONJ dti-1356 37 10 dysmotility dysmotility NOUN dti-1356 37 11 over over ADP dti-1356 37 12 a a DET dti-1356 37 13 2 2 NUM dti-1356 37 14 - - PUNCT dti-1356 37 15 year year NOUN dti-1356 37 16 period period NOUN dti-1356 37 17 ( ( PUNCT dti-1356 37 18 2003–2004 2003–2004 NUM dti-1356 37 19 ) ) PUNCT dti-1356 37 20 were be AUX dti-1356 37 21 investigated investigate VERB dti-1356 37 22 depending depend VERB dti-1356 37 23 on on ADP dti-1356 37 24 the the DET dti-1356 37 25 severity severity NOUN dti-1356 37 26 of of ADP dti-1356 37 27 the the DET dti-1356 37 28 symptoms.12 symptoms.12 NOUN dti-1356 37 29 they they PRON dti-1356 37 30 underwent undergo VERB dti-1356 37 31 extensive extensive ADJ dti-1356 37 32 examinations examination NOUN dti-1356 37 33 to to PART dti-1356 37 34 exclude exclude VERB dti-1356 37 35 organic organic ADJ dti-1356 37 36 gastrointestinal gastrointestinal ADJ dti-1356 37 37 disorders disorder NOUN dti-1356 37 38 , , PUNCT dti-1356 37 39 eg eg NOUN dti-1356 37 40 endoscopy endoscopy NOUN dti-1356 37 41 , , PUNCT dti-1356 37 42 radiologic radiologic ADJ dti-1356 37 43 examination examination NOUN dti-1356 37 44 , , PUNCT dti-1356 37 45 and and CCONJ dti-1356 37 46 abdominal abdominal ADJ dti-1356 37 47 ultrasound ultrasound NOUN dti-1356 37 48 . . PUNCT dti-1356 38 1 this this PRON dti-1356 38 2 had have AUX dti-1356 38 3 been be AUX dti-1356 38 4 performed perform VERB dti-1356 38 5 repeatedly repeatedly ADV dti-1356 38 6 for for ADP dti-1356 38 7 several several ADJ dti-1356 38 8 years year NOUN dti-1356 38 9 in in ADP dti-1356 38 10 some some DET dti-1356 38 11 cases case NOUN dti-1356 38 12 . . PUNCT dti-1356 39 1 routine routine ADJ dti-1356 39 2 blood blood NOUN dti-1356 39 3 and and CCONJ dti-1356 39 4 urine urine NOUN dti-1356 39 5 samples sample NOUN dti-1356 39 6 were be AUX dti-1356 39 7 analyzed analyze VERB dti-1356 39 8 . . PUNCT dti-1356 40 1 the the DET dti-1356 40 2 gastrointestinal gastrointestinal ADJ dti-1356 40 3 examination examination NOUN dti-1356 40 4 was be AUX dti-1356 40 5 then then ADV dti-1356 40 6 further far ADV dti-1356 40 7 complemented complement VERB dti-1356 40 8 in in ADP dti-1356 40 9 order order NOUN dti-1356 40 10 to to PART dti-1356 40 11 evaluate evaluate VERB dti-1356 40 12 gastrointestinal gastrointestinal ADJ dti-1356 40 13 motility motility NOUN dti-1356 40 14 by by ADP dti-1356 40 15 manometry manometry NOUN dti-1356 40 16 , , PUNCT dti-1356 40 17 gastric gastric ADJ dti-1356 40 18 transit transit NOUN dti-1356 40 19 time time NOUN dti-1356 40 20 , , PUNCT dti-1356 40 21 and and CCONJ dti-1356 40 22 full full ADJ dti-1356 40 23 - - PUNCT dti-1356 40 24 thickness thickness NOUN dti-1356 40 25 biopsies biopsy NOUN dti-1356 40 26 of of ADP dti-1356 40 27 the the DET dti-1356 40 28 bowel bowel NOUN dti-1356 40 29 wall wall NOUN dti-1356 40 30 , , PUNCT dti-1356 40 31 depending depend VERB dti-1356 40 32 on on ADP dti-1356 40 33 the the DET dti-1356 40 34 clinical clinical ADJ dti-1356 40 35 picture.5,18–22 picture.5,18–22 NOUN dti-1356 40 36 patients patient NOUN dti-1356 40 37 with with ADP dti-1356 40 38 functional functional ADJ dti-1356 40 39 sub sub NOUN dti-1356 40 40 - - NOUN dti-1356 40 41 occlusion occlusion NOUN dti-1356 40 42 without without ADP dti-1356 40 43 mechanical mechanical ADJ dti-1356 40 44 obstruction obstruction NOUN dti-1356 40 45 , , PUNCT dti-1356 40 46 but but CCONJ dti-1356 40 47 abnormality abnormality NOUN dti-1356 40 48 in in ADP dti-1356 40 49 the the DET dti-1356 40 50 antroduodenal antroduodenal ADJ dti-1356 40 51 manometry manometry NOUN dti-1356 40 52 , , PUNCT dti-1356 40 53 were be AUX dti-1356 40 54 diagnosed diagnose VERB dti-1356 40 55 as as ADP dti-1356 40 56 having have VERB dti-1356 40 57 chronic chronic ADJ dti-1356 40 58 intestinal intestinal ADJ dti-1356 40 59 pseudo pseudo NOUN dti-1356 40 60 - - NOUN dti-1356 40 61 obstruction obstruction NOUN dti-1356 40 62 ( ( PUNCT dti-1356 40 63 cipo).23 cipo).23 VERB dti-1356 40 64 the the DET dti-1356 40 65 criterion criterion NOUN dti-1356 40 66 for for ADP dti-1356 40 67 enteric enteric ADJ dti-1356 40 68 dysmotility dysmotility NOUN dti-1356 40 69 ( ( PUNCT dti-1356 40 70 ed ed NOUN dti-1356 40 71 ) ) PUNCT dti-1356 40 72 was be AUX dti-1356 40 73 abnormality abnormality NOUN dti-1356 40 74 in in ADP dti-1356 40 75 the the DET dti-1356 40 76 small small ADJ dti-1356 40 77 bowel bowel NOUN dti-1356 40 78 manometry manometry NOUN dti-1356 40 79 , , PUNCT dti-1356 40 80 without without ADP dti-1356 40 81 sub sub NOUN dti-1356 40 82 - - ADJ dti-1356 40 83 occlusion occlusion ADJ dti-1356 40 84 episodes.24 episodes.24 NOUN dti-1356 40 85 the the DET dti-1356 40 86 diagnosis diagnosis NOUN dti-1356 40 87 idiopathic idiopathic ADJ dti-1356 40 88 gastroparesis gastroparesis NOUN dti-1356 40 89 was be AUX dti-1356 40 90 set set VERB dti-1356 40 91 when when SCONJ dti-1356 40 92 delayed delay VERB dti-1356 40 93 gastric gastric ADJ dti-1356 40 94 emptying empty VERB dti-1356 40 95 rate rate NOUN dti-1356 40 96 was be AUX dti-1356 40 97 the the DET dti-1356 40 98 only only ADJ dti-1356 40 99 finding finding NOUN dti-1356 40 100 , , PUNCT dti-1356 40 101 without without ADP dti-1356 40 102 engagement engagement NOUN dti-1356 40 103 of of ADP dti-1356 40 104 other other ADJ dti-1356 40 105 segments segment NOUN dti-1356 40 106 . . PUNCT dti-1356 41 1 patients patient NOUN dti-1356 41 2 with with ADP dti-1356 41 3 gastrointestinal gastrointestinal ADJ dti-1356 41 4 symptoms symptom NOUN dti-1356 41 5 fulfilling fulfil VERB dti-1356 41 6 the the DET dti-1356 41 7 rome rome PROPN dti-1356 41 8 - - PUNCT dti-1356 41 9 iii iii NUM dti-1356 41 10 criteria criterion NOUN dti-1356 41 11 , , PUNCT dti-1356 41 12 with with ADP dti-1356 41 13 no no DET dti-1356 41 14 abnormal abnormal ADJ dti-1356 41 15 pattern pattern NOUN dti-1356 41 16 on on ADP dti-1356 41 17 antroduodenal antroduodenal ADJ dti-1356 41 18 manometry manometry NOUN dti-1356 41 19 , , PUNCT dti-1356 41 20 were be AUX dti-1356 41 21 diagnosed diagnose VERB dti-1356 41 22 as as ADP dti-1356 41 23 having have VERB dti-1356 41 24 ibs.1 ibs.1 NOUN dti-1356 41 25 patients patient NOUN dti-1356 41 26 were be AUX dti-1356 41 27 invited invite VERB dti-1356 41 28 to to PART dti-1356 41 29 participate participate VERB dti-1356 41 30 in in ADP dti-1356 41 31 the the DET dti-1356 41 32 study study NOUN dti-1356 41 33 when when SCONJ dti-1356 41 34 organic organic ADJ dti-1356 41 35 , , PUNCT dti-1356 41 36 gastrointestinal gastrointestinal ADJ dti-1356 41 37 diseases disease NOUN dti-1356 41 38 were be AUX dti-1356 41 39 excluded exclude VERB dti-1356 41 40 , , PUNCT dti-1356 41 41 and and CCONJ dti-1356 41 42 one one NUM dti-1356 41 43 of of ADP dti-1356 41 44 the the DET dti-1356 41 45 above above ADV dti-1356 41 46 - - PUNCT dti-1356 41 47 mentioned mention VERB dti-1356 41 48 diagnoses diagnosis NOUN dti-1356 41 49 was be AUX dti-1356 41 50 set set VERB dti-1356 41 51 . . PUNCT dti-1356 42 1 patients patient NOUN dti-1356 42 2 suffering suffer VERB dti-1356 42 3 from from ADP dti-1356 42 4 diabetes diabetes NOUN dti-1356 42 5 mellitus mellitus NOUN dti-1356 42 6 . . PUNCT dti-1356 43 1 consecutive consecutive ADJ dti-1356 43 2 patients patient NOUN dti-1356 43 3 suffering suffer VERB dti-1356 43 4 from from ADP dti-1356 43 5 gastrointestinal gastrointestinal ADJ dti-1356 43 6 complaints complaint NOUN dti-1356 43 7 in in ADP dti-1356 43 8 addition addition NOUN dti-1356 43 9 to to ADP dti-1356 43 10 diabetes diabetes NOUN dti-1356 43 11 mellitus mellitus NOUN dti-1356 43 12 were be AUX dti-1356 43 13 examined examine VERB dti-1356 43 14 during during ADP dti-1356 43 15 2003–2004.2,12 2003–2004.2,12 NUM dti-1356 43 16 the the DET dti-1356 43 17 patients patient NOUN dti-1356 43 18 were be AUX dti-1356 43 19 examined examine VERB dti-1356 43 20 by by ADP dti-1356 43 21 gastroduodenoscopy gastroduodenoscopy NOUN dti-1356 43 22 , , PUNCT dti-1356 43 23 esophageal esophageal ADJ dti-1356 43 24 manometry manometry NOUN dti-1356 43 25 , , PUNCT dti-1356 43 26 and/or and/or CCONJ dti-1356 43 27 gastric gastric ADJ dti-1356 43 28 emptying empty VERB dti-1356 43 29 scintigraphy scintigraphy NOUN dti-1356 43 30 to to PART dti-1356 43 31 evaluate evaluate VERB dti-1356 43 32 the the DET dti-1356 43 33 gastrointestinal gastrointestinal NOUN dti-1356 43 34 motility.18–20,22 motility.18–20,22 NOUN dti-1356 43 35 patients patient NOUN dti-1356 43 36 diagnosed diagnose VERB dti-1356 43 37 as as ADP dti-1356 43 38 suffering suffer VERB dti-1356 43 39 from from ADP dti-1356 43 40 diabetes diabetes NOUN dti-1356 43 41 - - PUNCT dti-1356 43 42 related relate VERB dti-1356 43 43 dysmotility dysmotility NOUN dti-1356 43 44 , , PUNCT dti-1356 43 45 or or CCONJ dti-1356 43 46 who who PRON dti-1356 43 47 fulfilled fulfil VERB dti-1356 43 48 the the DET dti-1356 43 49 criteria criterion NOUN dti-1356 43 50 for for ADP dti-1356 43 51 ibs ib NOUN dti-1356 43 52 , , PUNCT dti-1356 43 53 were be AUX dti-1356 43 54 invited invite VERB dti-1356 43 55 to to PART dti-1356 43 56 participate participate VERB dti-1356 43 57 in in ADP dti-1356 43 58 the the DET dti-1356 43 59 study study NOUN dti-1356 43 60 . . PUNCT dti-1356 44 1 in in ADP dti-1356 44 2 addition addition NOUN dti-1356 44 3 , , PUNCT dti-1356 44 4 consecutive consecutive ADJ dti-1356 44 5 patients patient NOUN dti-1356 44 6 with with ADP dti-1356 44 7 diabetes diabetes NOUN dti-1356 44 8 mellitus mellitus NOUN dti-1356 44 9 , , PUNCT dti-1356 44 10 independent independent ADJ dti-1356 44 11 of of ADP dti-1356 44 12 the the DET dti-1356 44 13 presence presence NOUN dti-1356 44 14 or or CCONJ dti-1356 44 15 absence absence NOUN dti-1356 44 16 of of ADP dti-1356 44 17 gastrointestinal gastrointestinal ADJ dti-1356 44 18 symptoms symptom NOUN dti-1356 44 19 , , PUNCT dti-1356 44 20 were be AUX dti-1356 44 21 considered consider VERB dti-1356 44 22 for for ADP dti-1356 44 23 inclusion inclusion NOUN dti-1356 44 24 for for ADP dti-1356 44 25 a a DET dti-1356 44 26 further further ADJ dti-1356 44 27 2 2 NUM dti-1356 44 28 - - PUNCT dti-1356 44 29 year year NOUN dti-1356 44 30 period period NOUN dti-1356 44 31 . . PUNCT dti-1356 45 1 inclusion inclusion NOUN dti-1356 45 2 criteria criterion NOUN dti-1356 45 3 for for ADP dti-1356 45 4 the the DET dti-1356 45 5 study study NOUN dti-1356 45 6 were be AUX dti-1356 45 7 age age NOUN dti-1356 45 8 18 18 NOUN dti-1356 45 9     SPACE dti-1356 45 10 years year NOUN dti-1356 45 11 and and CCONJ dti-1356 45 12 diabetes diabetes NOUN dti-1356 45 13 mellitus mellitus NOUN dti-1356 45 14 . . PUNCT dti-1356 46 1 the the DET dti-1356 46 2 first first ADJ dti-1356 46 3 patient patient NOUN dti-1356 46 4 who who PRON dti-1356 46 5 fulfilled fulfil VERB dti-1356 46 6 the the DET dti-1356 46 7 criteria criterion NOUN dti-1356 46 8 at at ADP dti-1356 46 9 each each DET dti-1356 46 10 consultation consultation NOUN dti-1356 46 11 at at ADP dti-1356 46 12 the the DET dti-1356 46 13 section section NOUN dti-1356 46 14 of of ADP dti-1356 46 15 endocrinology endocrinology NOUN dti-1356 46 16 , , PUNCT dti-1356 46 17 skåne skåne PROPN dti-1356 46 18 university university PROPN dti-1356 46 19 hospital hospital NOUN dti-1356 46 20 , , PUNCT dti-1356 46 21 malmö malmö PROPN dti-1356 46 22 , , PUNCT dti-1356 46 23 january january PROPN dti-1356 46 24 2008 2008 NUM dti-1356 46 25 – – PUNCT dti-1356 46 26 february february PROPN dti-1356 46 27 2010 2010 NUM dti-1356 46 28 , , PUNCT dti-1356 46 29 was be AUX dti-1356 46 30 asked ask VERB dti-1356 46 31 to to PART dti-1356 46 32 take take VERB dti-1356 46 33 part part NOUN dti-1356 46 34 in in ADP dti-1356 46 35 the the DET dti-1356 46 36 study study NOUN dti-1356 46 37 when when SCONJ dti-1356 46 38 visiting visit VERB dti-1356 46 39 the the DET dti-1356 46 40 clinic clinic NOUN dti-1356 46 41 for for ADP dti-1356 46 42 routine routine ADJ dti-1356 46 43 follow follow NOUN dti-1356 46 44 - - PUNCT dti-1356 46 45 up up NOUN dti-1356 46 46 . . PUNCT dti-1356 47 1 exclusion exclusion NOUN dti-1356 47 2 criteria criterion NOUN dti-1356 47 3 were be AUX dti-1356 47 4 renal renal ADJ dti-1356 47 5 failure failure NOUN dti-1356 47 6 requiring require VERB dti-1356 47 7 dialysis dialysis NOUN dti-1356 47 8 and and CCONJ dti-1356 47 9 severe severe ADJ dti-1356 47 10 cardiac cardiac ADJ dti-1356 47 11 morbidity morbidity NOUN dti-1356 47 12 . . PUNCT dti-1356 48 1 examinations examination NOUN dti-1356 48 2 of of ADP dti-1356 48 3 esophageal esophageal ADJ dti-1356 48 4 motility motility NOUN dti-1356 48 5 and and CCONJ dti-1356 48 6 gastric gastric ADJ dti-1356 48 7 emptying empty VERB dti-1356 48 8 were be AUX dti-1356 48 9 performed.18–20,22 performed.18–20,22 X dti-1356 48 10 for for ADP dti-1356 48 11 further further ADJ dti-1356 48 12 description description NOUN dti-1356 48 13 of of ADP dti-1356 48 14 the the DET dti-1356 48 15 patients patient NOUN dti-1356 48 16 , , PUNCT dti-1356 48 17 see see VERB dti-1356 48 18 berntorp berntorp PROPN dti-1356 48 19 et et NOUN dti-1356 48 20 al.13 al.13 NOUN dti-1356 48 21 at at ADP dti-1356 48 22 the the DET dti-1356 48 23 time time NOUN dti-1356 48 24 of of ADP dti-1356 48 25 inclusion inclusion NOUN dti-1356 48 26 , , PUNCT dti-1356 48 27 all all DET dti-1356 48 28 patients patient NOUN dti-1356 48 29 with with ADP dti-1356 48 30 diabetes diabetes NOUN dti-1356 48 31 mellitus mellitus NOUN dti-1356 48 32 completed complete VERB dti-1356 48 33 a a DET dti-1356 48 34 questionnaire questionnaire NOUN dti-1356 48 35 concerning concern VERB dti-1356 48 36 symptoms symptom NOUN dti-1356 48 37 related relate VERB dti-1356 48 38 to to ADP dti-1356 48 39 disturbances disturbance NOUN dti-1356 48 40 of of ADP dti-1356 48 41 the the DET dti-1356 48 42 gastrointestinal gastrointestinal ADJ dti-1356 48 43 tract tract NOUN dti-1356 48 44 ( ( PUNCT dti-1356 48 45 “ " PUNCT dti-1356 48 46 loss loss NOUN dti-1356 48 47 of of ADP dti-1356 48 48 appetite appetite NOUN dti-1356 48 49 , , PUNCT dti-1356 48 50 swallowing swallow VERB dti-1356 48 51 disturbances disturbance NOUN dti-1356 48 52 , , PUNCT dti-1356 48 53 meal meal NOUN dti-1356 48 54 - - PUNCT dti-1356 48 55 related relate VERB dti-1356 48 56 cough cough NOUN dti-1356 48 57 , , PUNCT dti-1356 48 58 early early ADJ dti-1356 48 59 satiety satiety NOUN dti-1356 48 60 , , PUNCT dti-1356 48 61 nausea nausea NOUN dti-1356 48 62 , , PUNCT dti-1356 48 63 vomiting vomiting NOUN dti-1356 48 64 , , PUNCT dti-1356 48 65 weight weight NOUN dti-1356 48 66 loss loss NOUN dti-1356 48 67 , , PUNCT dti-1356 48 68 abdominal abdominal ADJ dti-1356 48 69 fullness fullness NOUN dti-1356 48 70 , , PUNCT dti-1356 48 71 bloating bloating NOUN dti-1356 48 72 , , PUNCT dti-1356 48 73 regurgitation regurgitation NOUN dti-1356 48 74 , , PUNCT dti-1356 48 75 constipation constipation NOUN dti-1356 48 76 , , PUNCT dti-1356 48 77 diarrhea diarrhea PROPN dti-1356 48 78 , , PUNCT dti-1356 48 79 evacuation evacuation NOUN dti-1356 48 80 incontinence incontinence NOUN dti-1356 48 81 , , PUNCT dti-1356 48 82 symptomatic symptomatic ADJ dti-1356 48 83 postprandial postprandial ADJ dti-1356 48 84 hypoglycemia hypoglycemia NOUN dti-1356 48 85 , , PUNCT dti-1356 48 86 and and CCONJ dti-1356 48 87 postprandial postprandial ADJ dti-1356 48 88 perspiration perspiration NOUN dti-1356 48 89 ” " PUNCT dti-1356 48 90 ) ) PUNCT dti-1356 48 91 , , PUNCT dti-1356 48 92 which which PRON dti-1356 48 93 had have AUX dti-1356 48 94 previously previously ADV dti-1356 48 95 been be AUX dti-1356 48 96 used use VERB dti-1356 48 97 for for ADP dti-1356 48 98 these these DET dti-1356 48 99 patients.2,25,26 patients.2,25,26 NOUN dti-1356 48 100 controls control NOUN dti-1356 48 101 . . PUNCT dti-1356 49 1 blood blood NOUN dti-1356 49 2 samples sample NOUN dti-1356 49 3 from from ADP dti-1356 49 4 200 200 NUM dti-1356 49 5 consecutive consecutive ADJ dti-1356 49 6 , , PUNCT dti-1356 49 7 healthy healthy ADJ dti-1356 49 8 blood blood NOUN dti-1356 49 9 donors donor NOUN dti-1356 49 10 ( ( PUNCT dti-1356 49 11 100 100 NUM dti-1356 49 12 women woman NOUN dti-1356 49 13 ) ) PUNCT dti-1356 49 14 , , PUNCT dti-1356 49 15 mean mean VERB dti-1356 49 16 age age NOUN dti-1356 49 17 of of ADP dti-1356 49 18 42 42 NUM dti-1356 49 19     SPACE dti-1356 49 20 ± ± NOUN dti-1356 49 21     SPACE dti-1356 49 22 13 13 NUM dti-1356 49 23     SPACE dti-1356 49 24 years year NOUN dti-1356 49 25 , , PUNCT dti-1356 49 26 were be AUX dti-1356 49 27 collected collect VERB dti-1356 49 28 at at ADP dti-1356 49 29 skåne skåne PROPN dti-1356 49 30 university university PROPN dti-1356 49 31 hospital hospital NOUN dti-1356 49 32 , , PUNCT dti-1356 49 33 malmö malmö PROPN dti-1356 49 34 , , PUNCT dti-1356 49 35 and and CCONJ dti-1356 49 36 provided provide VERB dti-1356 49 37 a a DET dti-1356 49 38 control control NOUN dti-1356 49 39 group group NOUN dti-1356 49 40 for for ADP dti-1356 49 41 the the DET dti-1356 49 42 antibody antibody NOUN dti-1356 49 43 analyses analysis NOUN dti-1356 49 44 . . PUNCT dti-1356 50 1 study study NOUN dti-1356 50 2 design design NOUN dti-1356 50 3 . . PUNCT dti-1356 51 1 the the DET dti-1356 51 2 patients patient NOUN dti-1356 51 3 and and CCONJ dti-1356 51 4 controls control NOUN dti-1356 51 5 gave give VERB dti-1356 51 6 a a DET dti-1356 51 7 blood blood NOUN dti-1356 51 8 sample sample NOUN dti-1356 51 9 , , PUNCT dti-1356 51 10 which which PRON dti-1356 51 11 consisted consist VERB dti-1356 51 12 of of ADP dti-1356 51 13 5.0 5.0 NUM dti-1356 51 14     SPACE dti-1356 51 15 ml ml NOUN dti-1356 51 16 blood blood NOUN dti-1356 51 17 drawn draw VERB dti-1356 51 18 into into ADP dti-1356 51 19 ssttubes ssttube NOUN dti-1356 51 20 ( ( PUNCT dti-1356 51 21 366566 366566 NUM dti-1356 51 22 , , PUNCT dti-1356 51 23 bd bd PROPN dti-1356 51 24 vacutainer vacutainer ADJ dti-1356 51 25 , , PUNCT dti-1356 51 26 plymouth plymouth PROPN dti-1356 51 27 , , PUNCT dti-1356 51 28 uk uk PROPN dti-1356 51 29 ) ) PUNCT dti-1356 51 30 containing contain VERB dti-1356 51 31 gel gel NOUN dti-1356 51 32 and and CCONJ dti-1356 51 33 a a DET dti-1356 51 34 coagulation coagulation NOUN dti-1356 51 35 activator activator NOUN dti-1356 51 36 . . PUNCT dti-1356 52 1 after after SCONJ dti-1356 52 2 the the DET dti-1356 52 3 tubes tube NOUN dti-1356 52 4 had have AUX dti-1356 52 5 been be AUX dti-1356 52 6 turned turn VERB dti-1356 52 7 10 10 NUM dti-1356 52 8 times time NOUN dti-1356 52 9 , , PUNCT dti-1356 52 10 they they PRON dti-1356 52 11 were be AUX dti-1356 52 12 centrifuged centrifuge VERB dti-1356 52 13 for for SCONJ dti-1356 52 14 15 15 NUM dti-1356 52 15     SPACE dti-1356 52 16 minutes minute NOUN dti-1356 52 17 at at ADP dti-1356 52 18 1,500 1,500 NUM dti-1356 52 19 g. g. NOUN dti-1356 52 20 serum serum NOUN dti-1356 52 21 was be AUX dti-1356 52 22 separated separate VERB dti-1356 52 23 , , PUNCT dti-1356 52 24 measured measure VERB dti-1356 52 25 into into ADP dti-1356 52 26 aliquots aliquot NOUN dti-1356 52 27 , , PUNCT dti-1356 52 28 and and CCONJ dti-1356 52 29 frozen freeze VERB dti-1356 52 30 at at ADP dti-1356 52 31 -20 -20 NUM dti-1356 52 32 ° ° NOUN dti-1356 52 33 c c NOUN dti-1356 52 34 and and CCONJ dti-1356 52 35 analyzed analyze VERB dti-1356 52 36 for for ADP dti-1356 52 37 the the DET dti-1356 52 38 expression expression NOUN dti-1356 52 39 of of ADP dti-1356 52 40 antibodies antibody NOUN dti-1356 52 41 . . PUNCT dti-1356 53 1 medical medical ADJ dti-1356 53 2 records record NOUN dti-1356 53 3 were be AUX dti-1356 53 4 reviewed review VERB dti-1356 53 5 concerning concern VERB dti-1356 53 6 duration duration NOUN dti-1356 53 7 of of ADP dti-1356 53 8 gastrointestinal gastrointestinal ADJ dti-1356 53 9 symptoms symptom NOUN dti-1356 53 10 , , PUNCT dti-1356 53 11 co co ADJ dti-1356 53 12 - - ADJ dti-1356 53 13 existing existing ADJ dti-1356 53 14 diseases disease NOUN dti-1356 53 15 , , PUNCT dti-1356 53 16 therapy therapy NOUN dti-1356 53 17 treatments treatment NOUN dti-1356 53 18 , , PUNCT dti-1356 53 19 hereditary hereditary ADJ dti-1356 53 20 factors factor NOUN dti-1356 53 21 , , PUNCT dti-1356 53 22 and and CCONJ dti-1356 53 23 routine routine ADJ dti-1356 53 24 laboratory laboratory NOUN dti-1356 53 25 analyses analysis NOUN dti-1356 53 26 . . PUNCT dti-1356 54 1 measurement measurement NOUN dti-1356 54 2 of of ADP dti-1356 54 3 antibodies antibody NOUN dti-1356 54 4 . . PUNCT dti-1356 55 1 analyses analysis NOUN dti-1356 55 2 of of ADP dti-1356 55 3 antibodies antibody NOUN dti-1356 55 4 ( ( PUNCT dti-1356 55 5 igm igm NOUN dti-1356 55 6 and and CCONJ dti-1356 55 7 igg igg PROPN dti-1356 55 8 ) ) PUNCT dti-1356 55 9 against against ADP dti-1356 55 10 gnrh1 gnrh1 PROPN dti-1356 55 11 , , PUNCT dti-1356 55 12 lh lh PROPN dti-1356 55 13 , , PUNCT dti-1356 55 14 and and CCONJ dti-1356 55 15 their their PRON dti-1356 55 16 receptors receptor NOUN dti-1356 55 17 were be AUX dti-1356 55 18 carried carry VERB dti-1356 55 19 out out ADP dti-1356 55 20 by by ADP dti-1356 55 21 elisas elisa NOUN dti-1356 55 22 developed develop VERB dti-1356 55 23 in in ADP dti-1356 55 24 - - PUNCT dti-1356 55 25 house house NOUN dti-1356 55 26 as as SCONJ dti-1356 55 27 described describe VERB dti-1356 55 28 previously.15,16 previously.15,16 NOUN dti-1356 55 29 serum serum NOUN dti-1356 55 30 was be AUX dti-1356 55 31 chosen choose VERB dti-1356 55 32 because because SCONJ dti-1356 55 33 heparin heparin ADJ dti-1356 55 34 and and CCONJ dti-1356 55 35 citrate citrate NOUN dti-1356 55 36 can can AUX dti-1356 55 37 affect affect VERB dti-1356 55 38 the the DET dti-1356 55 39 analyses analysis NOUN dti-1356 55 40 and and CCONJ dti-1356 55 41 because because SCONJ dti-1356 55 42 serum serum NOUN dti-1356 55 43 had have AUX dti-1356 55 44 been be AUX dti-1356 55 45 taken take VERB dti-1356 55 46 from from ADP dti-1356 55 47 the the DET dti-1356 55 48 control control NOUN dti-1356 55 49 group group NOUN dti-1356 55 50 . . PUNCT dti-1356 56 1 the the DET dti-1356 56 2 method method NOUN dti-1356 56 3 has have AUX dti-1356 56 4 been be AUX dti-1356 56 5 improved improve VERB dti-1356 56 6 from from ADP dti-1356 56 7 the the DET dti-1356 56 8 original original ADJ dti-1356 56 9 elisa elisa NOUN dti-1356 56 10 for for ADP dti-1356 56 11 gnrh gnrh NOUN dti-1356 56 12 antibodies,3,5,6,12,13 antibodies,3,5,6,12,13 PROPN dti-1356 56 13 and and CCONJ dti-1356 56 14 we we PRON dti-1356 56 15 now now ADV dti-1356 56 16 use use VERB dti-1356 56 17 gnrh gnrh NOUN dti-1356 56 18 conjugated conjugate VERB dti-1356 56 19 to to ADP dti-1356 56 20 ovalbumin ovalbumin PROPN dti-1356 56 21 ( ( PUNCT dti-1356 56 22 ova ova NOUN dti-1356 56 23 ) ) PUNCT dti-1356 56 24 ( ( PUNCT dti-1356 56 25 90215.02 90215.02 NUM dti-1356 56 26 , , PUNCT dti-1356 56 27 innovagen innovagen PROPN dti-1356 56 28 , , PUNCT dti-1356 56 29 lund lund PROPN dti-1356 56 30 , , PUNCT dti-1356 56 31 sweden sweden PROPN dti-1356 56 32 ) ) PUNCT dti-1356 56 33 with with ADP dti-1356 56 34 16 16 NUM dti-1356 56 35     SPACE dti-1356 56 36 mol mol ADP dti-1356 56 37 gnrh gnrh NOUN dti-1356 56 38 / / SYM dti-1356 56 39 mol mol ADP dti-1356 56 40 ova ova NOUN dti-1356 56 41 instead instead ADV dti-1356 56 42 of of ADP dti-1356 56 43 a a DET dti-1356 56 44 small small ADJ dti-1356 56 45 peptide peptide NOUN dti-1356 56 46 , , PUNCT dti-1356 56 47 ie ie X dti-1356 56 48 10 10 NUM dti-1356 56 49 amino amino ADJ dti-1356 56 50 acids acid NOUN dti-1356 56 51 , , PUNCT dti-1356 56 52 as as ADP dti-1356 56 53 antigen antigen ADV dti-1356 56 54 . . PUNCT dti-1356 57 1 this this PRON dti-1356 57 2 provides provide VERB dti-1356 57 3 a a DET dti-1356 57 4 more more ADV dti-1356 57 5 stable stable ADJ dti-1356 57 6 and and CCONJ dti-1356 57 7 efficient efficient ADJ dti-1356 57 8 analysis analysis NOUN dti-1356 57 9 . . PUNCT dti-1356 58 1 another another DET dti-1356 58 2 improvement improvement NOUN dti-1356 58 3 is be AUX dti-1356 58 4 the the DET dti-1356 58 5 calculation calculation NOUN dti-1356 58 6 of of ADP dti-1356 58 7 relative relative ADJ dti-1356 58 8 units unit NOUN dti-1356 58 9 ( ( PUNCT dti-1356 58 10 ru ru PROPN dti-1356 58 11 ) ) PUNCT dti-1356 58 12 from from ADP dti-1356 58 13 a a DET dti-1356 58 14 http://www.la-press.com http://www.la-press.com X dti-1356 58 15 http://www.la-press.com/drug-target-insights-journal-j23 http://www.la-press.com/drug-target-insights-journal-j23 PROPN dti-1356 58 16 the the DET dti-1356 58 17 expression expression NOUN dti-1356 58 18 of of ADP dti-1356 58 19 serum serum NOUN dti-1356 58 20 antibodies antibody NOUN dti-1356 58 21 against against ADP dti-1356 58 22 gnrh1 gnrh1 NOUN dti-1356 58 23 47drug 47drug X dti-1356 59 1 target target NOUN dti-1356 59 2 insights insight VERB dti-1356 59 3 2014:8 2014:8 NUM dti-1356 59 4 constructed construct VERB dti-1356 59 5 standard standard ADJ dti-1356 59 6 curve curve NOUN dti-1356 59 7 generated generate VERB dti-1356 59 8 from from ADP dti-1356 59 9 200 200 NUM dti-1356 59 10 blood blood NOUN dti-1356 59 11 donors donor NOUN dti-1356 59 12 , , PUNCT dti-1356 59 13 while while SCONJ dti-1356 59 14 in in ADP dti-1356 59 15 earlier early ADV dti-1356 59 16 studies3,5,6,12,13 studies3,5,6,12,13 NOUN dti-1356 59 17 any any DET dti-1356 59 18 value value NOUN dti-1356 59 19 above above ADP dti-1356 59 20 0 0 NUM dti-1356 59 21 was be AUX dti-1356 59 22 considered consider VERB dti-1356 59 23 positive positive ADJ dti-1356 59 24 . . PUNCT dti-1356 60 1 the the DET dti-1356 60 2 absorbance absorbance NOUN dti-1356 60 3 was be AUX dti-1356 60 4 measured measure VERB dti-1356 60 5 at at ADP dti-1356 60 6 405 405 NUM dti-1356 60 7     SPACE dti-1356 60 8 nm nm NOUN dti-1356 60 9 after after ADP dti-1356 60 10 30 30 NUM dti-1356 60 11     SPACE dti-1356 60 12 minutes minute NOUN dti-1356 60 13 ( ( PUNCT dti-1356 60 14 gnrh1 gnrh1 NOUN dti-1356 60 15 , , PUNCT dti-1356 60 16 gnrh gnrh NOUN dti-1356 60 17 receptor receptor NOUN dti-1356 60 18 , , PUNCT dti-1356 60 19 lh lh PROPN dti-1356 60 20 receptor receptor NOUN dti-1356 60 21 , , PUNCT dti-1356 60 22 and and CCONJ dti-1356 60 23 lh lh PROPN dti-1356 60 24 igm igm PROPN dti-1356 60 25 ) ) PUNCT dti-1356 60 26 or or CCONJ dti-1356 60 27 60 60 NUM dti-1356 60 28     SPACE dti-1356 60 29 minutes minute NOUN dti-1356 60 30 ( ( PUNCT dti-1356 60 31 lh lh PROPN dti-1356 60 32 igg igg PROPN dti-1356 60 33 ) ) PUNCT dti-1356 60 34 of of ADP dti-1356 60 35 incubation incubation NOUN dti-1356 60 36 at at ADP dti-1356 60 37 room room NOUN dti-1356 60 38 temperature temperature NOUN dti-1356 60 39 ( ( PUNCT dti-1356 60 40 rt rt PROPN dti-1356 60 41 ) ) PUNCT dti-1356 60 42 . . PUNCT dti-1356 61 1 the the DET dti-1356 61 2 grades grade NOUN dti-1356 61 3 of of ADP dti-1356 61 4 anti anti ADJ dti-1356 61 5 - - ADJ dti-1356 61 6 lh- lh- ADJ dti-1356 61 7 , , PUNCT dti-1356 61 8 anti anti ADJ dti-1356 61 9 - - ADJ dti-1356 61 10 gnrh1- gnrh1- ADJ dti-1356 61 11 , , PUNCT dti-1356 61 12 and and CCONJ dti-1356 61 13 anti anti ADJ dti-1356 61 14 - - ADJ dti-1356 61 15 gnrh gnrh NOUN dti-1356 61 16 receptor receptor NOUN dti-1356 61 17 antibodies antibody NOUN dti-1356 61 18 were be AUX dti-1356 61 19 calculated calculate VERB dti-1356 61 20 as as ADP dti-1356 61 21 ru ru NOUN dti-1356 61 22 based base VERB dti-1356 61 23 on on ADP dti-1356 61 24 each each DET dti-1356 61 25 standard standard ADJ dti-1356 61 26 curve curve NOUN dti-1356 61 27 . . PUNCT dti-1356 62 1 to to PART dti-1356 62 2 construct construct VERB dti-1356 62 3 standard standard ADJ dti-1356 62 4 curves curve NOUN dti-1356 62 5 , , PUNCT dti-1356 62 6 rabbit rabbit NOUN dti-1356 62 7 anti anti ADJ dti-1356 62 8 - - ADJ dti-1356 62 9 human human ADJ dti-1356 62 10 lh lh PROPN dti-1356 62 11 antibodies antibodie VERB dti-1356 62 12 ( ( PUNCT dti-1356 62 13 mbs535386 mbs535386 PROPN dti-1356 62 14 , , PUNCT dti-1356 62 15 mybiosource mybiosource PROPN dti-1356 62 16 , , PUNCT dti-1356 62 17 san san PROPN dti-1356 62 18 diego diego PROPN dti-1356 62 19 , , PUNCT dti-1356 62 20 ca ca PROPN dti-1356 62 21 , , PUNCT dti-1356 62 22 usa usa PROPN dti-1356 62 23 ) ) PUNCT dti-1356 62 24 were be AUX dti-1356 62 25 diluted dilute VERB dti-1356 62 26 from from ADP dti-1356 62 27 1:3,000 1:3,000 NUM dti-1356 62 28 to to ADP dti-1356 62 29 1:192,000 1:192,000 PROPN dti-1356 62 30 , , PUNCT dti-1356 62 31 mouse mouse NOUN dti-1356 62 32 anti anti ADJ dti-1356 62 33 - - ADJ dti-1356 62 34 human human ADJ dti-1356 62 35 gnrh gnrh NOUN dti-1356 62 36 antibodies antibodie VERB dti-1356 62 37 ( ( PUNCT dti-1356 62 38 ab62432 ab62432 PROPN dti-1356 62 39 , , PUNCT dti-1356 62 40 abcam abcam PROPN dti-1356 62 41 , , PUNCT dti-1356 62 42 cambridge cambridge PROPN dti-1356 62 43 , , PUNCT dti-1356 62 44 usa usa PROPN dti-1356 62 45 ) ) PUNCT dti-1356 62 46 were be AUX dti-1356 62 47 diluted dilute VERB dti-1356 62 48 from from ADP dti-1356 62 49 1:2,000 1:2,000 NUM dti-1356 62 50 to to ADP dti-1356 62 51 1:32,000 1:32,000 NUM dti-1356 62 52 , , PUNCT dti-1356 62 53 and and CCONJ dti-1356 62 54 rabbit rabbit NOUN dti-1356 62 55 anti anti ADJ dti-1356 62 56 - - ADJ dti-1356 62 57 human human ADJ dti-1356 62 58 gnrh gnrh NOUN dti-1356 62 59 receptor receptor NOUN dti-1356 62 60 antibodies antibodie VERB dti-1356 62 61 ( ( PUNCT dti-1356 62 62 90217.09 90217.09 NUM dti-1356 62 63 , , PUNCT dti-1356 62 64 innovagen innovagen NOUN dti-1356 62 65 ) ) PUNCT dti-1356 62 66 were be AUX dti-1356 62 67 diluted dilute VERB dti-1356 62 68 from from ADP dti-1356 62 69 1:8,000 1:8,000 NUM dti-1356 62 70 to to ADP dti-1356 62 71 1:128,000 1:128,000 NUM dti-1356 62 72 . . PUNCT dti-1356 63 1 antilh antilh PROPN dti-1356 63 2 receptor receptor NOUN dti-1356 63 3 antibodies antibody NOUN dti-1356 63 4 were be AUX dti-1356 63 5 calculated calculate VERB dti-1356 63 6 as as ADP dti-1356 63 7 absorbance absorbance NOUN dti-1356 63 8 values value NOUN dti-1356 63 9 multiplied multiply VERB dti-1356 63 10 by by ADP dti-1356 63 11 1,000 1,000 NUM dti-1356 63 12 . . PUNCT dti-1356 64 1 in in ADP dti-1356 64 2 both both DET dti-1356 64 3 cases case NOUN dti-1356 64 4 , , PUNCT dti-1356 64 5 the the DET dti-1356 64 6 background background NOUN dti-1356 64 7 values value NOUN dti-1356 64 8 of of ADP dti-1356 64 9 each each DET dti-1356 64 10 sample sample NOUN dti-1356 64 11 were be AUX dti-1356 64 12 subtracted subtract VERB dti-1356 64 13 before before ADP dti-1356 64 14 calculation calculation NOUN dti-1356 64 15 . . PUNCT dti-1356 65 1 the the DET dti-1356 65 2 cut cut VERB dti-1356 65 3 - - PUNCT dti-1356 65 4 off off ADP dti-1356 65 5 value value NOUN dti-1356 65 6 for for ADP dti-1356 65 7 the the DET dti-1356 65 8 presence presence NOUN dti-1356 65 9 of of ADP dti-1356 65 10 antibodies antibody NOUN dti-1356 65 11 in in ADP dti-1356 65 12 healthy healthy ADJ dti-1356 65 13 blood blood NOUN dti-1356 65 14 donors donor NOUN dti-1356 65 15 was be AUX dti-1356 65 16 set set VERB dti-1356 65 17 as as ADP dti-1356 65 18 ru ru NOUN dti-1356 65 19     SPACE dti-1356 65 20 97.5th 97.5th ADJ dti-1356 65 21 percentile percentile ADJ dti-1356 65 22 . . PUNCT dti-1356 66 1 the the DET dti-1356 66 2 intra intra ADJ dti-1356 66 3 - - ADJ dti-1356 66 4 assay assay ADJ dti-1356 66 5 correlation correlation NOUN dti-1356 66 6 coefficient coefficient NOUN dti-1356 66 7 of of ADP dti-1356 66 8 variation variation NOUN dti-1356 66 9 ( ( PUNCT dti-1356 66 10 cv cv NOUN dti-1356 66 11 ) ) PUNCT dti-1356 66 12 of of ADP dti-1356 66 13 gnrh gnrh NOUN dti-1356 66 14 and and CCONJ dti-1356 66 15 gnrh gnrh NOUN dti-1356 66 16 receptor receptor NOUN dti-1356 66 17 igm igm PROPN dti-1356 66 18 antibodies antibody NOUN dti-1356 66 19 was be AUX dti-1356 66 20 10 10 NUM dti-1356 66 21 % % NOUN dti-1356 66 22 and and CCONJ dti-1356 66 23 8 8 NUM dti-1356 66 24 % % NOUN dti-1356 66 25 , , PUNCT dti-1356 66 26 respectively respectively ADV dti-1356 66 27 ( ( PUNCT dti-1356 66 28 n n CCONJ dti-1356 66 29     SPACE dti-1356 66 30 = = NOUN dti-1356 66 31     SPACE dti-1356 66 32 6 6 NUM dti-1356 66 33 ) ) PUNCT dti-1356 66 34 , , PUNCT dti-1356 66 35 and and CCONJ dti-1356 66 36 the the DET dti-1356 66 37 inter inter ADJ dti-1356 66 38 - - ADJ dti-1356 66 39 assay assay ADJ dti-1356 66 40 cv cv PROPN dti-1356 66 41 was be AUX dti-1356 66 42 11 11 NUM dti-1356 66 43 % % NOUN dti-1356 66 44 and and CCONJ dti-1356 66 45 6 6 NUM dti-1356 66 46 % % NOUN dti-1356 66 47 , , PUNCT dti-1356 66 48 respectively respectively ADV dti-1356 66 49 ( ( PUNCT dti-1356 66 50 n n CCONJ dti-1356 66 51     SPACE dti-1356 66 52 = = NOUN dti-1356 66 53     SPACE dti-1356 66 54 12 12 NUM dti-1356 66 55 ) ) PUNCT dti-1356 66 56 . . PUNCT dti-1356 67 1 because because SCONJ dti-1356 67 2 of of ADP dti-1356 67 3 the the DET dti-1356 67 4 lack lack NOUN dti-1356 67 5 of of ADP dti-1356 67 6 positive positive ADJ dti-1356 67 7 serum serum NOUN dti-1356 67 8 , , PUNCT dti-1356 67 9 no no DET dti-1356 67 10 intra intra ADJ dti-1356 67 11 - - ADJ dti-1356 67 12 assay assay ADJ dti-1356 67 13 or or CCONJ dti-1356 67 14 inter inter ADJ dti-1356 67 15 - - ADJ dti-1356 67 16 assay assay ADJ dti-1356 67 17 cv cv PROPN dti-1356 67 18 of of ADP dti-1356 67 19 igg igg PROPN dti-1356 67 20 antibodies antibody NOUN dti-1356 67 21 was be AUX dti-1356 67 22 calculated calculate VERB dti-1356 67 23 . . PUNCT dti-1356 68 1 the the DET dti-1356 68 2 intra intra ADJ dti-1356 68 3 - - ADJ dti-1356 68 4 assay assay ADJ dti-1356 68 5 cv cv PROPN dti-1356 68 6 of of ADP dti-1356 68 7 lh lh PROPN dti-1356 68 8 igg igg PROPN dti-1356 68 9 and and CCONJ dti-1356 68 10 lh lh PROPN dti-1356 68 11 igm igm PROPN dti-1356 68 12 was be AUX dti-1356 68 13 5.6 5.6 NUM dti-1356 68 14 % % NOUN dti-1356 68 15 and and CCONJ dti-1356 68 16 9.2 9.2 NUM dti-1356 68 17 % % NOUN dti-1356 68 18 , , PUNCT dti-1356 68 19 respectively respectively ADV dti-1356 68 20 ( ( PUNCT dti-1356 68 21 n n CCONJ dti-1356 68 22     SPACE dti-1356 68 23 = = NOUN dti-1356 68 24     SPACE dti-1356 68 25 8) 8) NUM dti-1356 68 26 , , PUNCT dti-1356 68 27 and and CCONJ dti-1356 68 28 the the DET dti-1356 68 29 inter inter ADJ dti-1356 68 30 - - ADJ dti-1356 68 31 assay assay ADJ dti-1356 68 32 cv cv PROPN dti-1356 68 33 was be AUX dti-1356 68 34 7.7 7.7 NUM dti-1356 68 35 % % NOUN dti-1356 68 36 and and CCONJ dti-1356 68 37 6.1 6.1 NUM dti-1356 68 38 % % NOUN dti-1356 68 39 , , PUNCT dti-1356 68 40 respectively respectively ADV dti-1356 68 41 ( ( PUNCT dti-1356 68 42 n n CCONJ dti-1356 68 43     SPACE dti-1356 68 44 = = NOUN dti-1356 68 45     SPACE dti-1356 68 46 17 17 NUM dti-1356 68 47 ) ) PUNCT dti-1356 68 48 . . PUNCT dti-1356 69 1 because because SCONJ dti-1356 69 2 of of ADP dti-1356 69 3 the the DET dti-1356 69 4 lack lack NOUN dti-1356 69 5 of of ADP dti-1356 69 6 an an DET dti-1356 69 7 appropriate appropriate ADJ dti-1356 69 8 commercial commercial ADJ dti-1356 69 9 antibody antibody NOUN dti-1356 69 10 , , PUNCT dti-1356 69 11 no no DET dti-1356 69 12 intra intra ADJ dti-1356 69 13 - - ADJ dti-1356 69 14 assay assay ADJ dti-1356 69 15 or or CCONJ dti-1356 69 16 inter inter ADJ dti-1356 69 17 - - ADJ dti-1356 69 18 assay assay ADJ dti-1356 69 19 cv cv PROPN dti-1356 69 20 of of ADP dti-1356 69 21 lh lh PROPN dti-1356 69 22 receptor receptor NOUN dti-1356 69 23 was be AUX dti-1356 69 24 calculated calculate VERB dti-1356 69 25 . . PUNCT dti-1356 70 1 since since SCONJ dti-1356 70 2 antibodies antibody NOUN dti-1356 70 3 against against ADP dti-1356 70 4 lh lh PROPN dti-1356 70 5 and and CCONJ dti-1356 70 6 lh lh PROPN dti-1356 70 7 receptors receptor NOUN dti-1356 70 8 were be AUX dti-1356 70 9 not not PART dti-1356 70 10 expressed express VERB dti-1356 70 11 in in ADP dti-1356 70 12 patients patient NOUN dti-1356 70 13 with with ADP dti-1356 70 14 diabetes diabetes NOUN dti-1356 70 15 mellitus mellitus NOUN dti-1356 70 16 , , PUNCT dti-1356 70 17 these these DET dti-1356 70 18 analyses analysis NOUN dti-1356 70 19 were be AUX dti-1356 70 20 omitted omit VERB dti-1356 70 21 in in ADP dti-1356 70 22 our our PRON dti-1356 70 23 ibs ibs PROPN dti-1356 70 24 and and CCONJ dti-1356 70 25 dysmotility dysmotility NOUN dti-1356 70 26 patients patient NOUN dti-1356 70 27 . . PUNCT dti-1356 71 1 to to PART dti-1356 71 2 perform perform VERB dti-1356 71 3 competitive competitive ADJ dti-1356 71 4 elisa elisa NOUN dti-1356 71 5 , , PUNCT dti-1356 71 6 sera sera NOUN dti-1356 71 7 from from ADP dti-1356 71 8 patients patient NOUN dti-1356 71 9 with with ADP dti-1356 71 10 antibodies antibody NOUN dti-1356 71 11 above above ADP dti-1356 71 12 the the DET dti-1356 71 13 cut cut VERB dti-1356 71 14 - - PUNCT dti-1356 71 15 off off ADP dti-1356 71 16 level level NOUN dti-1356 71 17 were be AUX dti-1356 71 18 incubated incubate VERB dti-1356 71 19 with with ADP dti-1356 71 20 0.5 0.5 NUM dti-1356 71 21 % % NOUN dti-1356 71 22 bovine bovine NOUN dti-1356 71 23 serum serum NOUN dti-1356 71 24 albumin albumin PROPN dti-1356 71 25 ( ( PUNCT dti-1356 71 26 bsa bsa PROPN dti-1356 71 27 ) ) PUNCT dti-1356 71 28 in in ADP dti-1356 71 29 phosphate phosphate NOUN dti-1356 71 30 - - PUNCT dti-1356 71 31 buffered buffer VERB dti-1356 71 32 saline saline NOUN dti-1356 71 33 ( ( PUNCT dti-1356 71 34 pbs)-t pbs)-t NOUN dti-1356 71 35 with with ADP dti-1356 71 36 various various ADJ dti-1356 71 37 amounts amount NOUN dti-1356 71 38 of of ADP dti-1356 71 39 gnrh1 gnrh1 PROPN dti-1356 71 40 , , PUNCT dti-1356 71 41 gnrh gnrh NOUN dti-1356 71 42 receptor receptor NOUN dti-1356 71 43 , , PUNCT dti-1356 71 44 or or CCONJ dti-1356 71 45 lh lh PROPN dti-1356 71 46 receptor receptor NOUN dti-1356 71 47 , , PUNCT dti-1356 71 48 all all DET dti-1356 71 49 three three NUM dti-1356 71 50 both both CCONJ dti-1356 71 51 conjugated conjugate VERB dti-1356 71 52 and and CCONJ dti-1356 71 53 unconjugated unconjugate VERB dti-1356 71 54 with with ADP dti-1356 71 55 an an DET dti-1356 71 56 ova ova ADJ dti-1356 71 57 peptide peptide NOUN dti-1356 71 58 ( ( PUNCT dti-1356 71 59 innovagen innovagen PROPN dti-1356 71 60 ) ) PUNCT dti-1356 71 61 or or CCONJ dti-1356 71 62 lh lh PROPN dti-1356 71 63 ( ( PUNCT dti-1356 71 64 mbs537383 mbs537383 PROPN dti-1356 71 65 , , PUNCT dti-1356 71 66 mybiosource mybiosource PROPN dti-1356 71 67 ) ) PUNCT dti-1356 71 68 , , PUNCT dti-1356 71 69 ie ie X dti-1356 71 70 50 50 NUM dti-1356 71 71 , , PUNCT dti-1356 71 72 100 100 NUM dti-1356 71 73 , , PUNCT dti-1356 71 74 or or CCONJ dti-1356 71 75 200 200 NUM dti-1356 71 76 ng/100 ng/100 NOUN dti-1356 71 77 μl μl ADP dti-1356 71 78 , , PUNCT dti-1356 71 79 30 30 NUM dti-1356 71 80     SPACE dti-1356 71 81 minutes minute NOUN dti-1356 71 82 prior prior ADV dti-1356 71 83 to to ADP dti-1356 71 84 the the DET dti-1356 71 85 application application NOUN dti-1356 71 86 to to ADP dti-1356 71 87 the the DET dti-1356 71 88 microtiter microtiter NOUN dti-1356 71 89 plates plate NOUN dti-1356 71 90 . . PUNCT dti-1356 72 1 a a DET dti-1356 72 2 new new ADJ dti-1356 72 3 in in ADP dti-1356 72 4 - - PUNCT dti-1356 72 5 house house NOUN dti-1356 72 6 elisa elisa NOUN dti-1356 72 7 was be AUX dti-1356 72 8 set set VERB dti-1356 72 9 up up ADP dti-1356 72 10 for for ADP dti-1356 72 11 the the DET dti-1356 72 12 analysis analysis NOUN dti-1356 72 13 of of ADP dti-1356 72 14 igm igm PROPN dti-1356 72 15 antibodies antibodie VERB dti-1356 72 16 against against ADP dti-1356 72 17 progonadoliberin-2 progonadoliberin-2 NUM dti-1356 72 18 , , PUNCT dti-1356 72 19 the the DET dti-1356 72 20 precursor precursor NOUN dti-1356 72 21 of of ADP dti-1356 72 22 gnrh2.17 gnrh2.17 PROPN dti-1356 72 23 the the DET dti-1356 72 24 microtiter microtiter NOUN dti-1356 72 25 plates plate NOUN dti-1356 72 26 ( ( PUNCT dti-1356 72 27 456537 456537 NUM dti-1356 72 28 , , PUNCT dti-1356 72 29 nunc nunc NOUN dti-1356 72 30 , , PUNCT dti-1356 72 31 roskilde roskilde NOUN dti-1356 72 32 , , PUNCT dti-1356 72 33 denmark denmark NOUN dti-1356 72 34 ) ) PUNCT dti-1356 72 35 were be AUX dti-1356 72 36 provided provide VERB dti-1356 72 37 with with ADP dti-1356 72 38 a a DET dti-1356 72 39 layer layer NOUN dti-1356 72 40 of of ADP dti-1356 72 41 recombinant recombinant ADJ dti-1356 72 42 progonadoliberin-2 progonadoliberin-2 NUM dti-1356 72 43 ( ( PUNCT dti-1356 72 44 mbs1014236 mbs1014236 ADJ dti-1356 72 45 , , PUNCT dti-1356 72 46 mybiosource mybiosource NOUN dti-1356 72 47 ) ) PUNCT dti-1356 72 48 in in ADP dti-1356 72 49 pbs pbs PROPN dti-1356 72 50 or or CCONJ dti-1356 72 51 pbs pbs PROPN dti-1356 72 52 only only ADV dti-1356 72 53 ( ( PUNCT dti-1356 72 54 an an DET dti-1356 72 55 internal internal ADJ dti-1356 72 56 blank blank NOUN dti-1356 72 57 ) ) PUNCT dti-1356 72 58 . . PUNCT dti-1356 73 1 after after ADP dti-1356 73 2 an an DET dti-1356 73 3 overnight overnight ADJ dti-1356 73 4 incubation incubation NOUN dti-1356 73 5 at at ADP dti-1356 73 6 4 4 NUM dti-1356 73 7 ° ° NOUN dti-1356 73 8 c c NOUN dti-1356 73 9 , , PUNCT dti-1356 73 10 the the DET dti-1356 73 11 plates plate NOUN dti-1356 73 12 were be AUX dti-1356 73 13 washed wash VERB dti-1356 73 14 three three NUM dti-1356 73 15 times time NOUN dti-1356 73 16 with with ADP dti-1356 73 17 pbs pbs PROPN dti-1356 73 18 - - PUNCT dti-1356 73 19 t t PROPN dti-1356 73 20 and and CCONJ dti-1356 73 21 thereafter thereafter ADV dti-1356 73 22 blocked block VERB dti-1356 73 23 with with ADP dti-1356 73 24 0.5 0.5 NUM dti-1356 73 25 % % NOUN dti-1356 73 26 bsa bsa NOUN dti-1356 73 27 ( ( PUNCT dti-1356 73 28 a7030 a7030 PROPN dti-1356 73 29 , , PUNCT dti-1356 73 30 sigma sigma PROPN dti-1356 73 31 , , PUNCT dti-1356 73 32 st st PROPN dti-1356 73 33 louis louis PROPN dti-1356 73 34 , , PUNCT dti-1356 73 35 usa usa PROPN dti-1356 73 36 ) ) PUNCT dti-1356 73 37 in in ADP dti-1356 73 38 pbs pbs PROPN dti-1356 73 39 - - PUNCT dti-1356 73 40 t. t. PROPN dti-1356 73 41 sera sera NOUN dti-1356 73 42 from from ADP dti-1356 73 43 patients patient NOUN dti-1356 73 44 and and CCONJ dti-1356 73 45 healthy healthy ADJ dti-1356 73 46 blood blood NOUN dti-1356 73 47 donors donor NOUN dti-1356 73 48 diluted dilute VERB dti-1356 73 49 to to ADP dti-1356 73 50 1:400 1:400 NUM dti-1356 73 51 , , PUNCT dti-1356 73 52 or or CCONJ dti-1356 73 53 igg igg PROPN dti-1356 73 54 antibodies antibody NOUN dti-1356 73 55 against against ADP dti-1356 73 56 human human ADJ dti-1356 73 57 gnrh2 gnrh2 PROPN dti-1356 73 58 raised raise VERB dti-1356 73 59 in in ADP dti-1356 73 60 rabbits rabbit NOUN dti-1356 73 61 ( ( PUNCT dti-1356 73 62 mbs6004097 mbs6004097 X dti-1356 73 63 , , PUNCT dti-1356 73 64 mybiosource mybiosource NOUN dti-1356 73 65 ) ) PUNCT dti-1356 73 66 in in ADP dti-1356 73 67 serial serial ADJ dti-1356 73 68 dilution dilution NOUN dti-1356 73 69 ( ( PUNCT dti-1356 73 70 to to PART dti-1356 73 71 provide provide VERB dti-1356 73 72 a a DET dti-1356 73 73 standard standard ADJ dti-1356 73 74 curve curve NOUN dti-1356 73 75 ) ) PUNCT dti-1356 73 76 with with ADP dti-1356 73 77 bsa bsa PROPN dti-1356 73 78 in in ADP dti-1356 73 79 pbs pbs PROPN dti-1356 73 80 - - PUNCT dti-1356 73 81 t t PROPN dti-1356 73 82 , , PUNCT dti-1356 73 83 were be AUX dti-1356 73 84 added add VERB dti-1356 73 85 to to ADP dti-1356 73 86 the the DET dti-1356 73 87 plates plate NOUN dti-1356 73 88 in in ADP dti-1356 73 89 triplicate triplicate PROPN dti-1356 73 90 ( ( PUNCT dti-1356 73 91 two two NUM dti-1356 73 92 wells well NOUN dti-1356 73 93 coated coat VERB dti-1356 73 94 with with ADP dti-1356 73 95 progonadoliberin-2 progonadoliberin-2 NUM dti-1356 73 96 and and CCONJ dti-1356 73 97 one one NUM dti-1356 73 98 well well ADV dti-1356 73 99 coated coat VERB dti-1356 73 100 with with ADP dti-1356 73 101 pbs pbs PROPN dti-1356 73 102 ) ) PUNCT dti-1356 73 103 and and CCONJ dti-1356 73 104 incubated incubate VERB dti-1356 73 105 at at ADP dti-1356 73 106 rt rt PROPN dti-1356 73 107 for for ADP dti-1356 73 108 2 2 NUM dti-1356 73 109     SPACE dti-1356 73 110 hours hour NOUN dti-1356 73 111 . . PUNCT dti-1356 74 1 the the DET dti-1356 74 2 washing washing NOUN dti-1356 74 3 procedure procedure NOUN dti-1356 74 4 was be AUX dti-1356 74 5 repeated repeat VERB dti-1356 74 6 , , PUNCT dti-1356 74 7 and and CCONJ dti-1356 74 8 the the DET dti-1356 74 9 deposition deposition NOUN dti-1356 74 10 of of ADP dti-1356 74 11 autoantibodies autoantibody NOUN dti-1356 74 12 directed direct VERB dti-1356 74 13 to to ADP dti-1356 74 14 progonadoliberin-2 progonadoliberin-2 NUM dti-1356 74 15 was be AUX dti-1356 74 16 detected detect VERB dti-1356 74 17 using use VERB dti-1356 74 18 biotinylated biotinylated ADJ dti-1356 74 19 , , PUNCT dti-1356 74 20 rabbit rabbit NOUN dti-1356 74 21 anti anti ADJ dti-1356 74 22 - - ADJ dti-1356 74 23 human human ADJ dti-1356 74 24 igm igm PROPN dti-1356 74 25 ( ( PUNCT dti-1356 74 26 673211 673211 NUM dti-1356 74 27 , , PUNCT dti-1356 74 28 mp mp NOUN dti-1356 74 29 biomedicals biomedical NOUN dti-1356 74 30 , , PUNCT dti-1356 74 31 santa santa PROPN dti-1356 74 32 ana ana PROPN dti-1356 74 33 , , PUNCT dti-1356 74 34 california california PROPN dti-1356 74 35 , , PUNCT dti-1356 74 36 usa usa PROPN dti-1356 74 37 ) ) PUNCT dti-1356 74 38 , , PUNCT dti-1356 74 39 or or CCONJ dti-1356 74 40 goat goat PROPN dti-1356 74 41 anti anti ADJ dti-1356 74 42 - - ADJ dti-1356 74 43 rabbit rabbit ADJ dti-1356 74 44 igg igg PROPN dti-1356 74 45 ( ( PUNCT dti-1356 74 46 b7389 b7389 PROPN dti-1356 74 47 , , PUNCT dti-1356 74 48 sigma sigma PROPN dti-1356 74 49 ) ) PUNCT dti-1356 74 50 , , PUNCT dti-1356 74 51 diluted dilute VERB dti-1356 74 52 in in ADP dti-1356 74 53 pbs pbs PROPN dti-1356 74 54 - - PROPN dti-1356 74 55 t. t. PROPN dti-1356 74 56 a a DET dti-1356 74 57 phosphatase phosphatase NOUN dti-1356 74 58 substrate substrate NOUN dti-1356 74 59 kit kit NOUN dti-1356 74 60 ( ( PUNCT dti-1356 74 61 37620 37620 NUM dti-1356 74 62 , , PUNCT dti-1356 74 63 pierce pierce PROPN dti-1356 74 64 , , PUNCT dti-1356 74 65 rockford rockford PROPN dti-1356 74 66 , , PUNCT dti-1356 74 67 il il PROPN dti-1356 74 68 , , PUNCT dti-1356 74 69 usa usa PROPN dti-1356 74 70 ) ) PUNCT dti-1356 74 71 was be AUX dti-1356 74 72 used use VERB dti-1356 74 73 to to PART dti-1356 74 74 develop develop VERB dti-1356 74 75 a a DET dti-1356 74 76 color color NOUN dti-1356 74 77 reaction reaction NOUN dti-1356 74 78 . . PUNCT dti-1356 75 1 the the DET dti-1356 75 2 absorbance absorbance NOUN dti-1356 75 3 was be AUX dti-1356 75 4 measured measure VERB dti-1356 75 5 at at ADP dti-1356 75 6 405 405 NUM dti-1356 75 7     SPACE dti-1356 75 8 mm mm NOUN dti-1356 75 9 after after ADP dti-1356 75 10 30 30 NUM dti-1356 75 11     SPACE dti-1356 75 12 minutes minute NOUN dti-1356 75 13 of of ADP dti-1356 75 14 incubation incubation NOUN dti-1356 75 15 at at ADP dti-1356 75 16 rt rt PROPN dti-1356 75 17 . . PUNCT dti-1356 76 1 antibody antibody NOUN dti-1356 76 2 levels level NOUN dti-1356 76 3 are be AUX dti-1356 76 4 presented present VERB dti-1356 76 5 as as ADP dti-1356 76 6 ru ru PROPN dti-1356 76 7 ( ( PUNCT dti-1356 76 8 values value NOUN dti-1356 76 9 after after ADP dti-1356 76 10 subtracted subtract VERB dti-1356 76 11 background background NOUN dti-1356 76 12 ) ) PUNCT dti-1356 76 13 , , PUNCT dti-1356 76 14 and and CCONJ dti-1356 76 15 the the DET dti-1356 76 16 concentration concentration NOUN dti-1356 76 17 in in ADP dti-1356 76 18 each each DET dti-1356 76 19 doublet doublet NOUN dti-1356 76 20 is be AUX dti-1356 76 21 interpolated interpolate VERB dti-1356 76 22 from from ADP dti-1356 76 23 the the DET dti-1356 76 24 standard standard ADJ dti-1356 76 25 curve curve NOUN dti-1356 76 26 . . PUNCT dti-1356 77 1 the the DET dti-1356 77 2 cut cut VERB dti-1356 77 3 - - PUNCT dti-1356 77 4 off off ADP dti-1356 77 5 value value NOUN dti-1356 77 6 to to PART dti-1356 77 7 define define VERB dti-1356 77 8 the the DET dti-1356 77 9 expression expression NOUN dti-1356 77 10 of of ADP dti-1356 77 11 antibodies antibody NOUN dti-1356 77 12 in in ADP dti-1356 77 13 the the DET dti-1356 77 14 healthy healthy ADJ dti-1356 77 15 blood blood NOUN dti-1356 77 16 donors donor NOUN dti-1356 77 17 was be AUX dti-1356 77 18 set set VERB dti-1356 77 19 to to PART dti-1356 77 20 ru ru VERB dti-1356 77 21 97.5th 97.5th ADJ dti-1356 77 22 percentile percentile ADJ dti-1356 77 23 . . PUNCT dti-1356 78 1 the the DET dti-1356 78 2 intra intra ADJ dti-1356 78 3 - - ADJ dti-1356 78 4 assay assay ADJ dti-1356 78 5 cv cv PROPN dti-1356 78 6 was be AUX dti-1356 78 7 5.7 5.7 NUM dti-1356 78 8 % % NOUN dti-1356 78 9 ( ( PUNCT dti-1356 78 10 n n CCONJ dti-1356 78 11     SPACE dti-1356 78 12 = = NOUN dti-1356 78 13     SPACE dti-1356 78 14 8) 8) NUM dti-1356 78 15 and and CCONJ dti-1356 78 16 inter inter ADJ dti-1356 78 17 - - ADJ dti-1356 78 18 assay assay ADJ dti-1356 78 19 cv cv PROPN dti-1356 78 20 was be AUX dti-1356 78 21 8.3 8.3 NUM dti-1356 78 22 % % NOUN dti-1356 78 23 ( ( PUNCT dti-1356 78 24 n n CCONJ dti-1356 78 25     SPACE dti-1356 78 26 = = NOUN dti-1356 78 27     SPACE dti-1356 78 28 8) 8) NUM dti-1356 78 29 . . PUNCT dti-1356 79 1 as as SCONJ dti-1356 79 2 igg igg PROPN dti-1356 79 3 antibodies antibodie VERB dti-1356 79 4 against against ADP dti-1356 79 5 gnrh1 gnrh1 NOUN dti-1356 79 6 or or CCONJ dti-1356 79 7 its its PRON dti-1356 79 8 receptor receptor NOUN dti-1356 79 9 have have AUX dti-1356 79 10 not not PART dti-1356 79 11 been be AUX dti-1356 79 12 shown show VERB dti-1356 79 13 to to PART dti-1356 79 14 be be AUX dti-1356 79 15 of of ADP dti-1356 79 16 importance importance NOUN dti-1356 79 17 in in ADP dti-1356 79 18 any any DET dti-1356 79 19 previous previous ADJ dti-1356 79 20 study study NOUN dti-1356 79 21 , , PUNCT dti-1356 79 22 those those PRON dti-1356 79 23 were be AUX dti-1356 79 24 not not PART dti-1356 79 25 analyzed analyze VERB dti-1356 79 26 for for ADP dti-1356 79 27 progonadoliberin-2 progonadoliberin-2 NUM dti-1356 79 28 . . PUNCT dti-1356 80 1 statistical statistical ADJ dti-1356 80 2 methods method NOUN dti-1356 80 3 . . PUNCT dti-1356 81 1 data datum NOUN dti-1356 81 2 are be AUX dti-1356 81 3 described describe VERB dti-1356 81 4 as as ADP dti-1356 81 5 mean mean NOUN dti-1356 81 6 ± ± NUM dti-1356 81 7 standard standard ADJ dti-1356 81 8 deviation deviation NOUN dti-1356 81 9 ( ( PUNCT dti-1356 81 10 sd sd NOUN dti-1356 81 11 ) ) PUNCT dti-1356 81 12 or or CCONJ dti-1356 81 13 median median NOUN dti-1356 81 14 ( ( PUNCT dti-1356 81 15 interquartile interquartile PROPN dti-1356 81 16 range range NOUN dti-1356 81 17 [ [ X dti-1356 81 18 iqr iqr X dti-1356 81 19 ] ] X dti-1356 81 20 ) ) PUNCT dti-1356 81 21 . . PUNCT dti-1356 82 1 fischer fischer PROPN dti-1356 82 2 ’s ’s PART dti-1356 82 3 exact exact ADJ dti-1356 82 4 test test NOUN dti-1356 82 5 was be AUX dti-1356 82 6 used use VERB dti-1356 82 7 for for ADP dti-1356 82 8 dichotomous dichotomous ADJ dti-1356 82 9 variables variable NOUN dti-1356 82 10 and and CCONJ dti-1356 82 11 the the DET dti-1356 82 12 mann mann PROPN dti-1356 82 13 – – PUNCT dti-1356 82 14 whitney whitney PROPN dti-1356 82 15 u u NOUN dti-1356 82 16 - - NOUN dti-1356 82 17 test test NOUN dti-1356 82 18 for for ADP dti-1356 82 19 continuous continuous ADJ dti-1356 82 20 variables variable NOUN dti-1356 82 21 . . PUNCT dti-1356 83 1 p p X dti-1356 83 2   PROPN dti-1356 83 3 0.05 0.05 NUM dti-1356 83 4 was be AUX dti-1356 83 5 considered consider VERB dti-1356 83 6 as as ADP dti-1356 83 7 statistically statistically ADV dti-1356 83 8 significant significant ADJ dti-1356 83 9 . . PUNCT dti-1356 84 1 results result VERB dti-1356 84 2 patients patient NOUN dti-1356 84 3 suffering suffer VERB dti-1356 84 4 from from ADP dti-1356 84 5 ibs ib NOUN dti-1356 84 6 or or CCONJ dti-1356 84 7 dysmotility dysmotility NOUN dti-1356 84 8 . . PUNCT dti-1356 85 1 forty forty NUM dti-1356 85 2 - - PUNCT dti-1356 85 3 five five NUM dti-1356 85 4 patients patient NOUN dti-1356 85 5 ( ( PUNCT dti-1356 85 6 37 37 NUM dti-1356 85 7 women woman NOUN dti-1356 85 8 [ [ X dti-1356 85 9 82 82 NUM dti-1356 85 10 % % NOUN dti-1356 85 11 ] ] X dti-1356 85 12 ) ) PUNCT dti-1356 85 13 , , PUNCT dti-1356 85 14 mean mean VERB dti-1356 85 15 age age NOUN dti-1356 85 16 43 43 NUM dti-1356 85 17     SPACE dti-1356 85 18 ± ± NOUN dti-1356 85 19     SPACE dti-1356 85 20 17 17 NUM dti-1356 85 21     SPACE dti-1356 85 22 years year NOUN dti-1356 85 23 , , PUNCT dti-1356 85 24 were be AUX dti-1356 85 25 included include VERB dti-1356 85 26 . . PUNCT dti-1356 86 1 the the DET dti-1356 86 2 mean mean ADJ dti-1356 86 3 duration duration NOUN dti-1356 86 4 of of ADP dti-1356 86 5 the the DET dti-1356 86 6 gastrointestinal gastrointestinal ADJ dti-1356 86 7 symptoms symptom NOUN dti-1356 86 8 was be AUX dti-1356 86 9 16 16 NUM dti-1356 86 10 ± ± NUM dti-1356 86 11 15 15 NUM dti-1356 86 12     SPACE dti-1356 86 13 years year NOUN dti-1356 86 14 . . PUNCT dti-1356 87 1 twenty twenty NUM dti-1356 87 2 - - PUNCT dti-1356 87 3 five five NUM dti-1356 87 4 patients patient NOUN dti-1356 87 5 were be AUX dti-1356 87 6 diagnosed diagnose VERB dti-1356 87 7 as as ADP dti-1356 87 8 having have VERB dti-1356 87 9 ibs ib NOUN dti-1356 87 10 , , PUNCT dti-1356 87 11 11 11 NUM dti-1356 87 12 of of ADP dti-1356 87 13 these these DET dti-1356 87 14 patients patient NOUN dti-1356 87 15 had have VERB dti-1356 87 16 the the DET dti-1356 87 17 alternating alternate VERB dti-1356 87 18 type type NOUN dti-1356 87 19 of of ADP dti-1356 87 20 ibs ibs PROPN dti-1356 87 21 ( ( PUNCT dti-1356 87 22 ibs ibs PROPN dti-1356 87 23 - - PUNCT dti-1356 87 24 a a NOUN dti-1356 87 25 ) ) PUNCT dti-1356 87 26 , , PUNCT dti-1356 87 27 eight eight NUM dti-1356 87 28 had have VERB dti-1356 87 29 constipation constipation NOUN dti-1356 87 30 - - PUNCT dti-1356 87 31 predominant predominant ADJ dti-1356 87 32 ibs ib NOUN dti-1356 87 33 ( ( PUNCT dti-1356 87 34 ibs ibs PROPN dti-1356 87 35 - - PUNCT dti-1356 87 36 c c NOUN dti-1356 87 37 ) ) PUNCT dti-1356 87 38 , , PUNCT dti-1356 87 39 and and CCONJ dti-1356 87 40 six six NUM dti-1356 87 41 had have VERB dti-1356 87 42 diarrhea diarrhea NOUN dti-1356 87 43 - - PUNCT dti-1356 87 44 predominant predominant ADJ dti-1356 87 45 ibs ibs PROPN dti-1356 87 46 ( ( PUNCT dti-1356 87 47 ibs ibs PROPN dti-1356 87 48 - - PUNCT dti-1356 87 49 d d PROPN dti-1356 87 50 ) ) PUNCT dti-1356 87 51 . . PUNCT dti-1356 88 1 twelve twelve NUM dti-1356 88 2 patients patient NOUN dti-1356 88 3 suffered suffer VERB dti-1356 88 4 from from ADP dti-1356 88 5 ed ed NOUN dti-1356 88 6 , , PUNCT dti-1356 88 7 five five NUM dti-1356 88 8 from from ADP dti-1356 88 9 cipo cipo NOUN dti-1356 88 10 , , PUNCT dti-1356 88 11 and and CCONJ dti-1356 88 12 three three NUM dti-1356 88 13 from from ADP dti-1356 88 14 idiopathic idiopathic ADJ dti-1356 88 15 gastroparesis gastroparesis NOUN dti-1356 88 16 ( ( PUNCT dti-1356 88 17 table table NOUN dti-1356 88 18 1 1 NUM dti-1356 88 19 ) ) PUNCT dti-1356 88 20 . . PUNCT dti-1356 89 1 apart apart ADV dti-1356 89 2 from from ADP dti-1356 89 3 the the DET dti-1356 89 4 gastrointestinal gastrointestinal ADJ dti-1356 89 5 diagnosis diagnosis NOUN dti-1356 89 6 , , PUNCT dti-1356 89 7 five five NUM dti-1356 89 8 patients patient NOUN dti-1356 89 9 had have VERB dti-1356 89 10 current current ADJ dti-1356 89 11 or or CCONJ dti-1356 89 12 recent recent ADJ dti-1356 89 13 treatment treatment NOUN dti-1356 89 14 for for ADP dti-1356 89 15 depression depression NOUN dti-1356 89 16 , , PUNCT dti-1356 89 17 and and CCONJ dti-1356 89 18 two two NUM dti-1356 89 19 cases case NOUN dti-1356 89 20 of of ADP dti-1356 89 21 each each PRON dti-1356 89 22 of of ADP dti-1356 89 23 the the DET dti-1356 89 24 following follow VERB dti-1356 89 25 diseases disease NOUN dti-1356 89 26 were be AUX dti-1356 89 27 noted note VERB dti-1356 89 28 : : PUNCT dti-1356 89 29 asthma asthma NOUN dti-1356 89 30 bronchialis bronchiali NOUN dti-1356 89 31 , , PUNCT dti-1356 89 32 table table NOUN dti-1356 89 33 1 1 NUM dti-1356 89 34 . . PUNCT dti-1356 90 1 the the DET dti-1356 90 2 expression expression NOUN dti-1356 90 3 of of ADP dti-1356 90 4 igm igm PROPN dti-1356 90 5 antibodies antibodie VERB dti-1356 90 6 in in ADP dti-1356 90 7 patients patient NOUN dti-1356 90 8 with with ADP dti-1356 90 9 ibs ib NOUN dti-1356 90 10 or or CCONJ dti-1356 90 11 dysmotility dysmotility NOUN dti-1356 90 12 . . PUNCT dti-1356 91 1 gnrh1 gnrh1 NOUN dti-1356 91 2 n n CCONJ dti-1356 91 3 ( ( PUNCT dti-1356 91 4 % % INTJ dti-1356 91 5 ) ) PUNCT dti-1356 91 6 progonadoliberin-2 progonadoliberin-2 NUM dti-1356 91 7 n n NOUN dti-1356 91 8 ( ( PUNCT dti-1356 91 9 % % INTJ dti-1356 91 10 ) ) PUNCT dti-1356 91 11 gnrh gnrh NOUN dti-1356 91 12 receptor receptor NOUN dti-1356 91 13 n n PROPN dti-1356 91 14 ( ( PUNCT dti-1356 91 15 % % INTJ dti-1356 91 16 ) ) PUNCT dti-1356 91 17 ibs ibs PROPN dti-1356 91 18 - - PUNCT dti-1356 91 19 a a X dti-1356 91 20 ( ( PUNCT dti-1356 91 21 n n NOUN dti-1356 91 22 = = SYM dti-1356 91 23 11 11 NUM dti-1356 91 24 ) ) PUNCT dti-1356 91 25 4 4 NUM dti-1356 91 26 ( ( PUNCT dti-1356 91 27 36 36 NUM dti-1356 91 28 ) ) PUNCT dti-1356 91 29 3 3 NUM dti-1356 91 30 ( ( PUNCT dti-1356 91 31 27 27 NUM dti-1356 91 32 ) ) SYM dti-1356 91 33 2 2 NUM dti-1356 91 34 ( ( PUNCT dti-1356 91 35 18 18 NUM dti-1356 91 36 ) ) PUNCT dti-1356 91 37 ibs ibs PROPN dti-1356 91 38 - - PUNCT dti-1356 91 39 c c PROPN dti-1356 91 40 ( ( PUNCT dti-1356 91 41 n n NOUN dti-1356 91 42 = = SYM dti-1356 91 43 8) 8) NUM dti-1356 91 44 1 1 NUM dti-1356 91 45 ( ( PUNCT dti-1356 91 46 12 12 NUM dti-1356 91 47 ) ) PUNCT dti-1356 91 48 ibs ibs PROPN dti-1356 91 49 - - PUNCT dti-1356 91 50 d d PROPN dti-1356 91 51 ( ( PUNCT dti-1356 91 52 n n NOUN dti-1356 91 53 = = SYM dti-1356 91 54 6 6 NUM dti-1356 91 55 ) ) PUNCT dti-1356 91 56 ed ed NOUN dti-1356 91 57 ( ( PUNCT dti-1356 91 58 n n NOUN dti-1356 91 59 = = NUM dti-1356 91 60 12 12 NUM dti-1356 91 61 ) ) PUNCT dti-1356 91 62 2 2 NUM dti-1356 91 63 ( ( PUNCT dti-1356 91 64 17 17 NUM dti-1356 91 65 ) ) SYM dti-1356 91 66 1 1 NUM dti-1356 91 67 ( ( PUNCT dti-1356 91 68 8) 8) NUM dti-1356 91 69 cipo cipo NOUN dti-1356 91 70 ( ( PUNCT dti-1356 91 71 n n NOUN dti-1356 91 72 = = SYM dti-1356 91 73 5 5 NUM dti-1356 91 74 ) ) PUNCT dti-1356 91 75 1 1 NUM dti-1356 91 76 ( ( PUNCT dti-1356 91 77 2 2 NUM dti-1356 91 78 ) ) PUNCT dti-1356 91 79 gastroparesis gastroparesis NOUN dti-1356 91 80 ( ( PUNCT dti-1356 91 81 n n NOUN dti-1356 91 82 = = SYM dti-1356 91 83 3 3 X dti-1356 91 84 ) ) PUNCT dti-1356 91 85 note note NOUN dti-1356 91 86 : : PUNCT dti-1356 91 87 the the DET dti-1356 91 88 cut cut VERB dti-1356 91 89 - - PUNCT dti-1356 91 90 off off ADP dti-1356 91 91 value value NOUN dti-1356 91 92 to to PART dti-1356 91 93 define define VERB dti-1356 91 94 the the DET dti-1356 91 95 expression expression NOUN dti-1356 91 96 of of ADP dti-1356 91 97 antibodies antibody NOUN dti-1356 91 98 in in ADP dti-1356 91 99 the the DET dti-1356 91 100 healthy healthy ADJ dti-1356 91 101 blood blood NOUN dti-1356 91 102 donors donor NOUN dti-1356 91 103 was be AUX dti-1356 91 104 set set VERB dti-1356 91 105 to to ADP dti-1356 91 106 relative relative ADJ dti-1356 91 107 unit unit NOUN dti-1356 91 108 ( ( PUNCT dti-1356 91 109 ru ru NOUN dti-1356 91 110 ) ) PUNCT dti-1356 91 111 97.5th 97.5th ADJ dti-1356 91 112 percentile percentile ADJ dti-1356 91 113 . . PUNCT dti-1356 92 1 abbreviations abbreviation NOUN dti-1356 92 2 : : PUNCT dti-1356 93 1 cipo cipo ADJ dti-1356 93 2 , , PUNCT dti-1356 93 3 chronic chronic ADJ dti-1356 93 4 intestinal intestinal ADJ dti-1356 93 5 pseudo pseudo NOUN dti-1356 93 6 - - NOUN dti-1356 93 7 obstruction obstruction NOUN dti-1356 93 8 ; ; PUNCT dti-1356 93 9 ed ed NOUN dti-1356 93 10 , , PUNCT dti-1356 93 11 enteric enteric ADJ dti-1356 93 12 dysmotility dysmotility NOUN dti-1356 93 13 ; ; PUNCT dti-1356 93 14 gnrh gnrh NOUN dti-1356 93 15 , , PUNCT dti-1356 93 16 gonadotropin gonadotropin NOUN dti-1356 93 17 - - PUNCT dti-1356 93 18 releasing release VERB dti-1356 93 19 hormone hormone NOUN dti-1356 93 20 ; ; PUNCT dti-1356 93 21 ibs ib NOUN dti-1356 93 22 - - PUNCT dti-1356 93 23 a a NOUN dti-1356 93 24 , , PUNCT dti-1356 93 25 alternating alternate VERB dti-1356 93 26 type type NOUN dti-1356 93 27 of of ADP dti-1356 93 28 ibs ib NOUN dti-1356 93 29 ; ; PUNCT dti-1356 93 30 ibs ibs PROPN dti-1356 93 31 - - PUNCT dti-1356 93 32 c c NOUN dti-1356 93 33 , , PUNCT dti-1356 93 34 constipation constipation NOUN dti-1356 93 35 - - PUNCT dti-1356 93 36 predominant predominant ADJ dti-1356 93 37 ibs ib NOUN dti-1356 93 38 ; ; PUNCT dti-1356 93 39 ibs ibs PROPN dti-1356 93 40 - - PUNCT dti-1356 93 41 d d PROPN dti-1356 93 42 , , PUNCT dti-1356 93 43 diarrhea diarrhea NOUN dti-1356 93 44 - - PUNCT dti-1356 93 45 predominant predominant ADJ dti-1356 93 46 ibs ib NOUN dti-1356 93 47 ; ; PUNCT dti-1356 93 48 n n CCONJ dti-1356 93 49 , , PUNCT dti-1356 93 50 number number NOUN dti-1356 93 51 . . PUNCT dti-1356 94 1 http://www.la-press.com http://www.la-press.com X dti-1356 95 1 http://www.la-press.com/drug-target-insights-journal-j23 http://www.la-press.com/drug-target-insights-journal-j23 PROPN dti-1356 95 2 roth roth PROPN dti-1356 95 3 et et PROPN dti-1356 95 4 al al PROPN dti-1356 95 5 48 48 NUM dti-1356 95 6 drug drug NOUN dti-1356 95 7 target target NOUN dti-1356 95 8 insights insight NOUN dti-1356 95 9 2014:8 2014:8 NUM dti-1356 95 10 endometriosis endometriosis NOUN dti-1356 95 11 , , PUNCT dti-1356 95 12 hypertension hypertension NOUN dti-1356 95 13 , , PUNCT dti-1356 95 14 hypothyroidism hypothyroidism NOUN dti-1356 95 15 , , PUNCT dti-1356 95 16 and and CCONJ dti-1356 95 17 rheumatologic rheumatologic NOUN dti-1356 95 18 diseases disease NOUN dti-1356 95 19 . . PUNCT dti-1356 96 1 other other ADJ dti-1356 96 2 sporadic sporadic ADJ dti-1356 96 3 diseases disease NOUN dti-1356 96 4 were be AUX dti-1356 96 5 migraine migraine ADJ dti-1356 96 6 , , PUNCT dti-1356 96 7 panic panic NOUN dti-1356 96 8 attacks attack NOUN dti-1356 96 9 , , PUNCT dti-1356 96 10 parkinson parkinson NOUN dti-1356 96 11 ’s ’s PART dti-1356 96 12 disease disease NOUN dti-1356 96 13 , , PUNCT dti-1356 96 14 and and CCONJ dti-1356 96 15 thyrotoxicosis thyrotoxicosis NOUN dti-1356 96 16 . . PUNCT dti-1356 97 1 all all DET dti-1356 97 2 routine routine ADJ dti-1356 97 3 blood blood NOUN dti-1356 97 4 samples sample NOUN dti-1356 97 5 were be AUX dti-1356 97 6 within within ADP dti-1356 97 7 the the DET dti-1356 97 8 reference reference NOUN dti-1356 97 9 values value NOUN dti-1356 97 10 ( ( PUNCT dti-1356 97 11 data datum NOUN dti-1356 97 12 not not PART dti-1356 97 13 shown show VERB dti-1356 97 14 ) ) PUNCT dti-1356 97 15 . . PUNCT dti-1356 98 1 patients patient NOUN dti-1356 98 2 suffering suffer VERB dti-1356 98 3 from from ADP dti-1356 98 4 diabetes diabetes NOUN dti-1356 98 5 mellitus mellitus NOUN dti-1356 98 6 and and CCONJ dti-1356 98 7 gastrointestinal gastrointestinal ADJ dti-1356 98 8 complaints complaint NOUN dti-1356 98 9 . . PUNCT dti-1356 99 1 nineteen nineteen NUM dti-1356 99 2 patients patient NOUN dti-1356 99 3 with with ADP dti-1356 99 4 diabetes diabetes NOUN dti-1356 99 5 mellitus mellitus NOUN dti-1356 99 6 and and CCONJ dti-1356 99 7 gastrointestinal gastrointestinal ADJ dti-1356 99 8 complaints complaint NOUN dti-1356 99 9 ( ( PUNCT dti-1356 99 10 10 10 NUM dti-1356 99 11 women woman NOUN dti-1356 99 12 [ [ X dti-1356 99 13 53 53 NUM dti-1356 99 14 % % NOUN dti-1356 99 15 ] ] X dti-1356 99 16 ) ) PUNCT dti-1356 99 17 , , PUNCT dti-1356 99 18 mean mean VERB dti-1356 99 19 age age NOUN dti-1356 99 20 50 50 NUM dti-1356 99 21     SPACE dti-1356 99 22 ± ± NOUN dti-1356 99 23     SPACE dti-1356 99 24 11 11 NUM dti-1356 99 25     SPACE dti-1356 99 26 years year NOUN dti-1356 99 27 , , PUNCT dti-1356 99 28 were be AUX dti-1356 99 29 included include VERB dti-1356 99 30 . . PUNCT dti-1356 100 1 the the DET dti-1356 100 2 mean mean ADJ dti-1356 100 3 duration duration NOUN dti-1356 100 4 of of ADP dti-1356 100 5 diabetes diabetes NOUN dti-1356 100 6 mellitus mellitus NOUN dti-1356 100 7 was be AUX dti-1356 100 8 31 31 NUM dti-1356 100 9     SPACE dti-1356 100 10 ± ± NOUN dti-1356 100 11     SPACE dti-1356 100 12 12 12 NUM dti-1356 100 13     SPACE dti-1356 100 14 years year NOUN dti-1356 100 15 , , PUNCT dti-1356 100 16 and and CCONJ dti-1356 100 17 of of ADP dti-1356 100 18 gastrointestinal gastrointestinal ADJ dti-1356 100 19 complaints complaint NOUN dti-1356 100 20 was be AUX dti-1356 100 21 5 5 NUM dti-1356 100 22     SPACE dti-1356 100 23 ± ± NOUN dti-1356 100 24     SPACE dti-1356 100 25 4 4 NUM dti-1356 100 26     SPACE dti-1356 100 27 years year NOUN dti-1356 100 28 . . PUNCT dti-1356 101 1 seventeen seventeen NUM dti-1356 101 2 patients patient NOUN dti-1356 101 3 had have AUX dti-1356 101 4 type type NOUN dti-1356 101 5 1 1 NUM dti-1356 101 6 diabetes diabetes NOUN dti-1356 101 7 and and CCONJ dti-1356 101 8 two two NUM dti-1356 101 9 had have VERB dti-1356 101 10 type type NOUN dti-1356 101 11 2 2 NUM dti-1356 101 12 diabetes diabetes NOUN dti-1356 101 13 . . PUNCT dti-1356 102 1 all all PRON dti-1356 102 2 were be AUX dti-1356 102 3 on on ADP dti-1356 102 4 insulin insulin NOUN dti-1356 102 5 treatment treatment NOUN dti-1356 102 6 and and CCONJ dti-1356 102 7 were be AUX dti-1356 102 8 under under ADP dti-1356 102 9 acceptable acceptable ADJ dti-1356 102 10 metabolic metabolic NOUN dti-1356 102 11 control control NOUN dti-1356 102 12 ( ( PUNCT dti-1356 102 13 hba1c hba1c NOUN dti-1356 102 14 : : PUNCT dti-1356 102 15 64.9 64.9 NUM dti-1356 102 16     SPACE dti-1356 102 17 ± ± NOUN dti-1356 102 18     SPACE dti-1356 102 19 10.1 10.1 NUM dti-1356 102 20     SPACE dti-1356 102 21 mmol mmol NOUN dti-1356 102 22 / / SYM dti-1356 102 23 mol mol NOUN dti-1356 102 24 ) ) PUNCT dti-1356 102 25 . . PUNCT dti-1356 103 1 all all DET dti-1356 103 2 19 19 NUM dti-1356 103 3 patients patient NOUN dti-1356 103 4 were be AUX dti-1356 103 5 examined examine VERB dti-1356 103 6 using use VERB dti-1356 103 7 gastric gastric ADJ dti-1356 103 8 emptying empty VERB dti-1356 103 9 scintigraphy scintigraphy NOUN dti-1356 103 10 , , PUNCT dti-1356 103 11 and and CCONJ dti-1356 103 12 12 12 NUM dti-1356 103 13 using use VERB dti-1356 103 14 esophageal esophageal ADJ dti-1356 103 15 manometry manometry NOUN dti-1356 103 16 . . PUNCT dti-1356 104 1 gastroparesis gastroparesis NOUN dti-1356 104 2 was be AUX dti-1356 104 3 found find VERB dti-1356 104 4 in in ADP dti-1356 104 5 10 10 NUM dti-1356 104 6 patients patient NOUN dti-1356 104 7 and and CCONJ dti-1356 104 8 esophageal esophageal ADJ dti-1356 104 9 dysmotility dysmotility NOUN dti-1356 104 10 in in ADP dti-1356 104 11 eight eight NUM dti-1356 104 12 patients patient NOUN dti-1356 104 13 . . PUNCT dti-1356 105 1 six six NUM dti-1356 105 2 of of ADP dti-1356 105 3 the the DET dti-1356 105 4 patients patient NOUN dti-1356 105 5 had have VERB dti-1356 105 6 abnormal abnormal ADJ dti-1356 105 7 findings finding NOUN dti-1356 105 8 in in ADP dti-1356 105 9 both both DET dti-1356 105 10 examinations examination NOUN dti-1356 105 11 , , PUNCT dti-1356 105 12 with with ADP dti-1356 105 13 no no DET dti-1356 105 14 correlation correlation NOUN dti-1356 105 15 between between ADP dti-1356 105 16 the the DET dti-1356 105 17 abnormalities abnormality NOUN dti-1356 105 18 in in ADP dti-1356 105 19 the the DET dti-1356 105 20 two two NUM dti-1356 105 21 organs organ NOUN dti-1356 105 22 . . PUNCT dti-1356 106 1 most most ADJ dti-1356 106 2 of of ADP dti-1356 106 3 the the DET dti-1356 106 4 patients patient NOUN dti-1356 106 5 also also ADV dti-1356 106 6 suffered suffer VERB dti-1356 106 7 from from ADP dti-1356 106 8 secondary secondary ADJ dti-1356 106 9 complications complication NOUN dti-1356 106 10 of of ADP dti-1356 106 11 diabetes diabetes NOUN dti-1356 106 12 mellitus mellitus NOUN dti-1356 106 13 , , PUNCT dti-1356 106 14 such such ADJ dti-1356 106 15 as as ADP dti-1356 106 16 retinopathy retinopathy ADJ dti-1356 106 17 ( ( PUNCT dti-1356 106 18 79 79 NUM dti-1356 106 19 % % NOUN dti-1356 106 20 ) ) PUNCT dti-1356 106 21 , , PUNCT dti-1356 106 22 autonomic autonomic ADJ dti-1356 106 23 neuropathy neuropathy ADJ dti-1356 106 24 ( ( PUNCT dti-1356 106 25 53 53 NUM dti-1356 106 26 % % NOUN dti-1356 106 27 ) ) PUNCT dti-1356 106 28 , , PUNCT dti-1356 106 29 and and CCONJ dti-1356 106 30 peripheral peripheral ADJ dti-1356 106 31 neuropathy neuropathy ADJ dti-1356 106 32 ( ( PUNCT dti-1356 106 33 47 47 NUM dti-1356 106 34 % % NOUN dti-1356 106 35 ) ) PUNCT dti-1356 106 36 . . PUNCT dti-1356 107 1 as as SCONJ dti-1356 107 2 some some PRON dti-1356 107 3 of of ADP dti-1356 107 4 the the DET dti-1356 107 5 patients patient NOUN dti-1356 107 6 with with ADP dti-1356 107 7 diabetes diabetes NOUN dti-1356 107 8 mellitus mellitus NOUN dti-1356 107 9 and and CCONJ dti-1356 107 10 gastrointestinal gastrointestinal ADJ dti-1356 107 11 complaints complaint NOUN dti-1356 107 12 had have VERB dti-1356 107 13 no no DET dti-1356 107 14 pathological pathological ADJ dti-1356 107 15 changes change NOUN dti-1356 107 16 as as SCONJ dti-1356 107 17 found find VERB dti-1356 107 18 in in ADP dti-1356 107 19 the the DET dti-1356 107 20 examinations examination NOUN dti-1356 107 21 ( ( PUNCT dti-1356 107 22 n n CCONJ dti-1356 107 23     SPACE dti-1356 107 24 = = NOUN dti-1356 107 25     SPACE dti-1356 107 26 3 3 NUM dti-1356 107 27 ) ) PUNCT dti-1356 107 28 , , PUNCT dti-1356 107 29 they they PRON dti-1356 107 30 were be AUX dti-1356 107 31 diagnosed diagnose VERB dti-1356 107 32 as as ADP dti-1356 107 33 ibs ib NOUN dti-1356 107 34 patients patient NOUN dti-1356 107 35 . . PUNCT dti-1356 108 1 the the DET dti-1356 108 2 most most ADV dti-1356 108 3 common common ADJ dti-1356 108 4 symptoms symptom NOUN dti-1356 108 5 were be AUX dti-1356 108 6 abdominal abdominal ADJ dti-1356 108 7 fullness fullness NOUN dti-1356 108 8 ( ( PUNCT dti-1356 108 9 95 95 NUM dti-1356 108 10 % % NOUN dti-1356 108 11 ) ) PUNCT dti-1356 108 12 , , PUNCT dti-1356 108 13 bloating bloat VERB dti-1356 108 14 ( ( PUNCT dti-1356 108 15 79 79 NUM dti-1356 108 16 % % NOUN dti-1356 108 17 ) ) PUNCT dti-1356 108 18 , , PUNCT dti-1356 108 19 early early ADJ dti-1356 108 20 satiety satiety NOUN dti-1356 108 21 ( ( PUNCT dti-1356 108 22 68 68 NUM dti-1356 108 23 % % NOUN dti-1356 108 24 ) ) PUNCT dti-1356 108 25 , , PUNCT dti-1356 108 26 and and CCONJ dti-1356 108 27 constipation constipation NOUN dti-1356 108 28 ( ( PUNCT dti-1356 108 29 68 68 NUM dti-1356 108 30 % % NOUN dti-1356 108 31 ) ) PUNCT dti-1356 108 32 . . PUNCT dti-1356 109 1 four four NUM dti-1356 109 2 of of ADP dti-1356 109 3 the the DET dti-1356 109 4 patients patient NOUN dti-1356 109 5 had have VERB dti-1356 109 6 hypertension hypertension NOUN dti-1356 109 7 , , PUNCT dti-1356 109 8 two two NUM dti-1356 109 9 had have VERB dti-1356 109 10 hypothyroditis hypothyroditis NOUN dti-1356 109 11 , , PUNCT dti-1356 109 12 two two NUM dti-1356 109 13 had have VERB dti-1356 109 14 chronic chronic ADJ dti-1356 109 15 pancreatitis pancreatitis NOUN dti-1356 109 16 , , PUNCT dti-1356 109 17 and and CCONJ dti-1356 109 18 one one NUM dti-1356 109 19 had have VERB dti-1356 109 20 atrophic atrophic ADJ dti-1356 109 21 gastritis gastritis NOUN dti-1356 109 22 , , PUNCT dti-1356 109 23 depression depression NOUN dti-1356 109 24 , , PUNCT dti-1356 109 25 hypopituitarism hypopituitarism NOUN dti-1356 109 26 , , PUNCT dti-1356 109 27 and and CCONJ dti-1356 109 28 rheumatoid rheumatoid VERB dti-1356 109 29 arthritis arthritis NOUN dti-1356 109 30 , , PUNCT dti-1356 109 31 respectively respectively ADV dti-1356 109 32 . . PUNCT dti-1356 110 1 patients patient NOUN dti-1356 110 2 suffering suffer VERB dti-1356 110 3 from from ADP dti-1356 110 4 diabetes diabetes NOUN dti-1356 110 5 mellitus mellitus NOUN dti-1356 110 6 . . PUNCT dti-1356 111 1 forty forty NUM dti-1356 111 2 patients patient NOUN dti-1356 111 3 with with ADP dti-1356 111 4 diabetes diabetes NOUN dti-1356 111 5 mellitus mellitus NOUN dti-1356 111 6 ( ( PUNCT dti-1356 111 7 27 27 NUM dti-1356 111 8 women woman NOUN dti-1356 111 9 [ [ X dti-1356 111 10 68 68 NUM dti-1356 111 11 % % NOUN dti-1356 111 12 ] ] PUNCT dti-1356 111 13 ) ) PUNCT dti-1356 111 14 , , PUNCT dti-1356 111 15 mean mean VERB dti-1356 111 16 age age NOUN dti-1356 111 17 51 51 NUM dti-1356 111 18 ± ± NUM dti-1356 111 19 13 13 NUM dti-1356 111 20     SPACE dti-1356 111 21 years year NOUN dti-1356 111 22 , , PUNCT dti-1356 111 23 were be AUX dti-1356 111 24 included include VERB dti-1356 111 25 in in ADP dti-1356 111 26 the the DET dti-1356 111 27 study study NOUN dti-1356 111 28 . . PUNCT dti-1356 112 1 the the DET dti-1356 112 2 patients patient NOUN dti-1356 112 3 were be AUX dti-1356 112 4 insulintreated insulintreate VERB dti-1356 112 5 ( ( PUNCT dti-1356 112 6 type type NOUN dti-1356 112 7 1 1 NUM dti-1356 112 8 diabetes diabetes NOUN dti-1356 112 9 : : PUNCT dti-1356 112 10 37 37 NUM dti-1356 112 11 patients patient NOUN dti-1356 112 12 [ [ X dti-1356 112 13 92 92 NUM dti-1356 112 14 % % NOUN dti-1356 112 15 ] ] PUNCT dti-1356 112 16 ) ) PUNCT dti-1356 112 17 and and CCONJ dti-1356 112 18 were be AUX dti-1356 112 19 under under ADP dti-1356 112 20 acceptable acceptable ADJ dti-1356 112 21 metabolic metabolic NOUN dti-1356 112 22 control control NOUN dti-1356 112 23 ( ( PUNCT dti-1356 112 24 hba1c hba1c PROPN dti-1356 112 25 : : PUNCT dti-1356 112 26 65.2 65.2 NUM dti-1356 112 27     SPACE dti-1356 112 28 ± ± NOUN dti-1356 112 29     SPACE dti-1356 112 30 9.5 9.5 NUM dti-1356 112 31     SPACE dti-1356 112 32 mmol mmol NOUN dti-1356 112 33 / / SYM dti-1356 112 34 mol mol NOUN dti-1356 112 35 ) ) PUNCT dti-1356 112 36 . . PUNCT dti-1356 113 1 the the DET dti-1356 113 2 duration duration NOUN dti-1356 113 3 of of ADP dti-1356 113 4 diabetes diabetes NOUN dti-1356 113 5 mellitus mellitus NOUN dti-1356 113 6 was be AUX dti-1356 113 7 26 26 NUM dti-1356 113 8 ± ± NUM dti-1356 113 9 13 13 NUM dti-1356 113 10     SPACE dti-1356 113 11 years year NOUN dti-1356 113 12 . . PUNCT dti-1356 114 1 esophageal esophageal ADJ dti-1356 114 2 dysmotility dysmotility NOUN dti-1356 114 3 was be AUX dti-1356 114 4 more more ADV dti-1356 114 5 often often ADV dti-1356 114 6 found find VERB dti-1356 114 7 ( ( PUNCT dti-1356 114 8 60 60 NUM dti-1356 114 9 % % NOUN dti-1356 114 10 ) ) PUNCT dti-1356 114 11 than than ADP dti-1356 114 12 gastroparesis gastroparesis NOUN dti-1356 114 13 ( ( PUNCT dti-1356 114 14 20 20 NUM dti-1356 114 15 % % NOUN dti-1356 114 16 ) ) PUNCT dti-1356 114 17 . . PUNCT dti-1356 115 1 twelve twelve NUM dti-1356 115 2 percent percent NOUN dti-1356 115 3 had have VERB dti-1356 115 4 dysmotility dysmotility NOUN dti-1356 115 5 in in ADP dti-1356 115 6 both both CCONJ dti-1356 115 7 esophagus esophagus NOUN dti-1356 115 8 and and CCONJ dti-1356 115 9 the the DET dti-1356 115 10 stomach stomach NOUN dti-1356 115 11 . . PUNCT dti-1356 116 1 the the DET dti-1356 116 2 most most ADV dti-1356 116 3 common common ADJ dti-1356 116 4 diabetes diabetes NOUN dti-1356 116 5 complication complication NOUN dti-1356 116 6 was be AUX dti-1356 116 7 retinopathy retinopathy ADJ dti-1356 116 8 ( ( PUNCT dti-1356 116 9 65 65 NUM dti-1356 116 10 % % NOUN dti-1356 116 11 ) ) PUNCT dti-1356 116 12 , , PUNCT dti-1356 116 13 followed follow VERB dti-1356 116 14 by by ADP dti-1356 116 15 peripheral peripheral ADJ dti-1356 116 16 neuropathy neuropathy ADJ dti-1356 116 17 ( ( PUNCT dti-1356 116 18 48 48 NUM dti-1356 116 19 % % NOUN dti-1356 116 20 ) ) PUNCT dti-1356 116 21 and and CCONJ dti-1356 116 22 angiopathy angiopathy ADJ dti-1356 116 23 ( ( PUNCT dti-1356 116 24 28 28 NUM dti-1356 116 25 % % NOUN dti-1356 116 26 ) ) PUNCT dti-1356 116 27 . . PUNCT dti-1356 117 1 although although SCONJ dti-1356 117 2 the the DET dti-1356 117 3 patients patient NOUN dti-1356 117 4 were be AUX dti-1356 117 5 included include VERB dti-1356 117 6 consecutively consecutively ADV dti-1356 117 7 , , PUNCT dti-1356 117 8 regardless regardless ADV dti-1356 117 9 of of ADP dti-1356 117 10 gastrointestinal gastrointestinal ADJ dti-1356 117 11 symptoms symptom NOUN dti-1356 117 12 , , PUNCT dti-1356 117 13 the the DET dti-1356 117 14 majority majority NOUN dti-1356 117 15 reported report VERB dti-1356 117 16 symptoms symptom NOUN dti-1356 117 17 related relate VERB dti-1356 117 18 to to ADP dti-1356 117 19 food food NOUN dti-1356 117 20 intake intake NOUN dti-1356 117 21 and and CCONJ dti-1356 117 22 the the DET dti-1356 117 23 gastrointestinal gastrointestinal ADJ dti-1356 117 24 tract tract NOUN dti-1356 117 25 . . PUNCT dti-1356 118 1 the the DET dti-1356 118 2 most most ADV dti-1356 118 3 common common ADJ dti-1356 118 4 symptoms symptom NOUN dti-1356 118 5 were be AUX dti-1356 118 6 bloating bloat VERB dti-1356 118 7 ( ( PUNCT dti-1356 118 8 48 48 NUM dti-1356 118 9 % % NOUN dti-1356 118 10 ) ) PUNCT dti-1356 118 11 , , PUNCT dti-1356 118 12 abdominal abdominal ADJ dti-1356 118 13 fullness fullness NOUN dti-1356 118 14 ( ( PUNCT dti-1356 118 15 40 40 NUM dti-1356 118 16 % % NOUN dti-1356 118 17 ) ) PUNCT dti-1356 118 18 , , PUNCT dti-1356 118 19 and and CCONJ dti-1356 118 20 early early ADJ dti-1356 118 21 satiety satiety NOUN dti-1356 118 22 ( ( PUNCT dti-1356 118 23 35 35 NUM dti-1356 118 24 % % NOUN dti-1356 118 25 ) ) PUNCT dti-1356 118 26 . . PUNCT dti-1356 119 1 apart apart ADV dti-1356 119 2 from from ADP dti-1356 119 3 diabetes diabetes NOUN dti-1356 119 4 mellitus mellitus NOUN dti-1356 119 5 , , PUNCT dti-1356 119 6 three three NUM dti-1356 119 7 patients patient NOUN dti-1356 119 8 suffered suffer VERB dti-1356 119 9 from from ADP dti-1356 119 10 hypothyroidism hypothyroidism NOUN dti-1356 119 11 and and CCONJ dti-1356 119 12 one one NUM dti-1356 119 13 from from ADP dti-1356 119 14 addison addison PROPN dti-1356 119 15 ’s ’s PART dti-1356 119 16 disease disease NOUN dti-1356 119 17 , , PUNCT dti-1356 119 18 atoxic atoxic ADV dti-1356 119 19 adenoma adenoma ADV dti-1356 119 20 , , PUNCT dti-1356 119 21 celiac celiac ADJ dti-1356 119 22 disease disease NOUN dti-1356 119 23 , , PUNCT dti-1356 119 24 pernicious pernicious ADJ dti-1356 119 25 anemia anemia NOUN dti-1356 119 26 , , PUNCT dti-1356 119 27 sjögren sjögren PROPN dti-1356 119 28 ’s ’s PART dti-1356 119 29 syndrome syndrome NOUN dti-1356 119 30 , , PUNCT dti-1356 119 31 thyrotoxicosis thyrotoxicosis NOUN dti-1356 119 32 , , PUNCT dti-1356 119 33 and and CCONJ dti-1356 119 34 vitiligo vitiligo VERB dti-1356 119 35 , , PUNCT dti-1356 119 36 respectively respectively ADV dti-1356 119 37 . . PUNCT dti-1356 120 1 serum serum PROPN dti-1356 120 2 antibodies antibodie VERB dti-1356 120 3 . . PUNCT dti-1356 121 1 the the DET dti-1356 121 2 distribution distribution NOUN dti-1356 121 3 of of ADP dti-1356 121 4 antibodies antibody NOUN dti-1356 121 5 among among ADP dti-1356 121 6 subgroups subgroup NOUN dti-1356 121 7 of of ADP dti-1356 121 8 ibs ibs PROPN dti-1356 121 9 or or CCONJ dti-1356 121 10 dysmotility dysmotility NOUN dti-1356 121 11 patients patient NOUN dti-1356 121 12 is be AUX dti-1356 121 13 shown show VERB dti-1356 121 14 in in ADP dti-1356 121 15 table table NOUN dti-1356 121 16 1 1 NUM dti-1356 121 17 . . PUNCT dti-1356 121 18 when when SCONJ dti-1356 121 19 calculated calculate VERB dti-1356 121 20 as as ADP dti-1356 121 21 a a DET dti-1356 121 22 whole whole ADJ dti-1356 121 23 group group NOUN dti-1356 121 24 , , PUNCT dti-1356 121 25 they they PRON dti-1356 121 26 had have VERB dti-1356 121 27 a a DET dti-1356 121 28 higher high ADJ dti-1356 121 29 prevalence prevalence NOUN dti-1356 121 30 of of ADP dti-1356 121 31 igm igm PROPN dti-1356 121 32 antibodies antibody NOUN dti-1356 121 33 against against ADP dti-1356 121 34 gnrh1 gnrh1 NOUN dti-1356 121 35 and and CCONJ dti-1356 121 36 progonadoliberin-2 progonadoliberin-2 NUM dti-1356 121 37 , , PUNCT dti-1356 121 38 and and CCONJ dti-1356 121 39 a a DET dti-1356 121 40 tendency tendency NOUN dti-1356 121 41 to to ADP dti-1356 121 42 a a DET dti-1356 121 43 higher high ADJ dti-1356 121 44 prevalence prevalence NOUN dti-1356 121 45 of of ADP dti-1356 121 46 igm igm PROPN dti-1356 121 47 antibodies antibody NOUN dti-1356 121 48 against against ADP dti-1356 121 49 gnrh gnrh NOUN dti-1356 121 50 receptor receptor NOUN dti-1356 121 51 , , PUNCT dti-1356 121 52 than than ADP dti-1356 121 53 healthy healthy ADJ dti-1356 121 54 controls control NOUN dti-1356 121 55 ( ( PUNCT dti-1356 121 56 table table NOUN dti-1356 121 57 2 2 NUM dti-1356 121 58 ) ) PUNCT dti-1356 121 59 . . PUNCT dti-1356 122 1 the the DET dti-1356 122 2 expression expression NOUN dti-1356 122 3 of of ADP dti-1356 122 4 igg igg PROPN dti-1356 122 5 antibodies antibodie VERB dti-1356 122 6 against against ADP dti-1356 122 7 gnrh1 gnrh1 NOUN dti-1356 122 8 and and CCONJ dti-1356 122 9 gnrh gnrh NOUN dti-1356 122 10 receptor receptor NOUN dti-1356 122 11 did do AUX dti-1356 122 12 not not PART dti-1356 122 13 differ differ VERB dti-1356 122 14 from from ADP dti-1356 122 15 that that PRON dti-1356 122 16 of of ADP dti-1356 122 17 the the DET dti-1356 122 18 controls control NOUN dti-1356 122 19 ( ( PUNCT dti-1356 122 20 p p X dti-1356 122 21     SPACE dti-1356 122 22 = = NOUN dti-1356 122 23     SPACE dti-1356 122 24 1.000 1.000 NUM dti-1356 122 25 and and CCONJ dti-1356 122 26 p p X dti-1356 122 27     SPACE dti-1356 122 28 = = NOUN dti-1356 122 29     SPACE dti-1356 122 30 0.625 0.625 NUM dti-1356 122 31 , , PUNCT dti-1356 122 32 respectively respectively ADV dti-1356 122 33 ) ) PUNCT dti-1356 122 34 . . PUNCT dti-1356 123 1 the the DET dti-1356 123 2 expression expression NOUN dti-1356 123 3 of of ADP dti-1356 123 4 any any PRON dti-1356 123 5 of of ADP dti-1356 123 6 the the DET dti-1356 123 7 antibodies antibody NOUN dti-1356 123 8 was be AUX dti-1356 123 9 not not PART dti-1356 123 10 associated associate VERB dti-1356 123 11 with with ADP dti-1356 123 12 age age NOUN dti-1356 123 13 ( ( PUNCT dti-1356 123 14 p p X dti-1356 123 15     SPACE dti-1356 123 16 = = NOUN dti-1356 123 17     SPACE dti-1356 123 18 0.311 0.311 NUM dti-1356 123 19 ) ) PUNCT dti-1356 123 20 , , PUNCT dti-1356 123 21 duration duration NOUN dti-1356 123 22 of of ADP dti-1356 123 23 symptoms symptom NOUN dti-1356 123 24 ( ( PUNCT dti-1356 123 25 p p X dti-1356 123 26     SPACE dti-1356 123 27 = = NOUN dti-1356 123 28     SPACE dti-1356 123 29 0.743 0.743 NUM dti-1356 123 30 ) ) PUNCT dti-1356 123 31 , , PUNCT dti-1356 123 32 or or CCONJ dti-1356 123 33 subgroup subgroup NOUN dti-1356 123 34 of of ADP dti-1356 123 35 patients patient NOUN dti-1356 123 36 ( ( PUNCT dti-1356 123 37 p p X dti-1356 123 38     SPACE dti-1356 123 39 = = NOUN dti-1356 123 40     SPACE dti-1356 123 41 0.353 0.353 NUM dti-1356 123 42 ) ) PUNCT dti-1356 123 43 . . PUNCT dti-1356 124 1 when when SCONJ dti-1356 124 2 comparing compare VERB dti-1356 124 3 patients patient NOUN dti-1356 124 4 with with ADP dti-1356 124 5 ibs ibs PROPN dti-1356 124 6 and and CCONJ dti-1356 124 7 dysmotility dysmotility NOUN dti-1356 124 8 , , PUNCT dti-1356 124 9 the the DET dti-1356 124 10 prevalence prevalence NOUN dti-1356 124 11 of of ADP dti-1356 124 12 antibodies antibody NOUN dti-1356 124 13 was be AUX dti-1356 124 14 equal equal ADJ dti-1356 124 15 ( ( PUNCT dti-1356 124 16 p p X dti-1356 124 17     SPACE dti-1356 124 18 = = NOUN dti-1356 124 19     SPACE dti-1356 124 20 1.000 1.000 NUM dti-1356 124 21 ) ) PUNCT dti-1356 124 22 . . PUNCT dti-1356 125 1 patients patient NOUN dti-1356 125 2 with with ADP dti-1356 125 3 gastrointestinal gastrointestinal ADJ dti-1356 125 4 complaints complaint NOUN dti-1356 125 5 related relate VERB dti-1356 125 6 to to ADP dti-1356 125 7 diabetes diabetes NOUN dti-1356 125 8 mellitus mellitus NOUN dti-1356 125 9 only only ADV dti-1356 125 10 expressed express VERB dti-1356 125 11 igm igm PROPN dti-1356 125 12 antibodies antibody NOUN dti-1356 125 13 against against ADP dti-1356 125 14 gnrh1 gnrh1 NOUN dti-1356 125 15 , , PUNCT dti-1356 125 16 prevalence prevalence NOUN dti-1356 125 17 of of ADP dti-1356 125 18 which which PRON dti-1356 125 19 tended tend VERB dti-1356 125 20 to to PART dti-1356 125 21 be be AUX dti-1356 125 22 significantly significantly ADV dti-1356 125 23 elevated elevate VERB dti-1356 125 24 compared compare VERB dti-1356 125 25 with with ADP dti-1356 125 26 controls control NOUN dti-1356 125 27 ( ( PUNCT dti-1356 125 28 table table NOUN dti-1356 125 29 2 2 NUM dti-1356 125 30 ) ) PUNCT dti-1356 125 31 . . PUNCT dti-1356 126 1 consecutive consecutive ADJ dti-1356 126 2 patients patient NOUN dti-1356 126 3 with with ADP dti-1356 126 4 diabetes diabetes NOUN dti-1356 126 5 mellitus mellitus NOUN dti-1356 126 6 had have VERB dti-1356 126 7 a a DET dti-1356 126 8 higher high ADJ dti-1356 126 9 prevalence prevalence NOUN dti-1356 126 10 of of ADP dti-1356 126 11 igm igm PROPN dti-1356 126 12 antibodies antibodie VERB dti-1356 126 13 against against ADP dti-1356 126 14 progonadoliberin-2 progonadoliberin-2 NUM dti-1356 126 15 than than ADP dti-1356 126 16 controls control NOUN dti-1356 126 17 ( ( PUNCT dti-1356 126 18 table table NOUN dti-1356 126 19 2 2 NUM dti-1356 126 20 ) ) PUNCT dti-1356 126 21 , , PUNCT dti-1356 126 22 whereas whereas SCONJ dti-1356 126 23 the the DET dti-1356 126 24 expression expression NOUN dti-1356 126 25 of of ADP dti-1356 126 26 igm igm PROPN dti-1356 126 27 and and CCONJ dti-1356 126 28 igg igg PROPN dti-1356 126 29 antibodies antibody NOUN dti-1356 126 30 against against ADP dti-1356 126 31 gnrh1 gnrh1 NOUN dti-1356 126 32 was be AUX dti-1356 126 33 equal equal ADJ dti-1356 126 34 ( ( PUNCT dti-1356 126 35 p p X dti-1356 126 36     SPACE dti-1356 126 37 = = NOUN dti-1356 126 38     SPACE dti-1356 126 39 1.000 1.000 NUM dti-1356 126 40 and and CCONJ dti-1356 126 41 p p X dti-1356 126 42     SPACE dti-1356 126 43 = = NOUN dti-1356 126 44     SPACE dti-1356 126 45 1.000 1.000 NUM dti-1356 126 46 , , PUNCT dti-1356 126 47 respectively respectively ADV dti-1356 126 48 ) ) PUNCT dti-1356 126 49 . . PUNCT dti-1356 127 1 except except SCONJ dti-1356 127 2 for for ADP dti-1356 127 3 a a DET dti-1356 127 4 tendency tendency NOUN dti-1356 127 5 toward toward ADP dti-1356 127 6 a a DET dti-1356 127 7 shorter short ADJ dti-1356 127 8 half half ADJ dti-1356 127 9 - - PUNCT dti-1356 127 10 time time NOUN dti-1356 127 11 of of ADP dti-1356 127 12 gastric gastric ADJ dti-1356 127 13 emptying empty VERB dti-1356 127 14 rate rate NOUN dti-1356 127 15 in in ADP dti-1356 127 16 patients patient NOUN dti-1356 127 17 with with ADP dti-1356 127 18 antibodies antibody NOUN dti-1356 127 19 against against ADP dti-1356 127 20 progonadoliberin-2 progonadoliberin-2 NUM dti-1356 127 21 ( ( PUNCT dti-1356 127 22 27.0 27.0 NUM dti-1356 127 23 [ [ X dti-1356 127 24 26.0–50.5 26.0–50.5 NUM dti-1356 127 25 ] ] PUNCT dti-1356 127 26 and and CCONJ dti-1356 127 27 52.5 52.5 NUM dti-1356 127 28 [ [ X dti-1356 127 29 36.2–71.438 36.2–71.438 NUM dti-1356 127 30 ] ] X dti-1356 127 31 , , PUNCT dti-1356 127 32 respectively respectively ADV dti-1356 127 33 , , PUNCT dti-1356 127 34 p p X dti-1356 127 35     SPACE dti-1356 127 36 = = NOUN dti-1356 127 37     SPACE dti-1356 127 38 0.056 0.056 NUM dti-1356 127 39 ) ) PUNCT dti-1356 127 40 , , PUNCT dti-1356 127 41 no no DET dti-1356 127 42 other other ADJ dti-1356 127 43 clinical clinical ADJ dti-1356 127 44 associations association NOUN dti-1356 127 45 could could AUX dti-1356 127 46 be be AUX dti-1356 127 47 found find VERB dti-1356 127 48 . . PUNCT dti-1356 128 1 none none NOUN dti-1356 128 2 of of ADP dti-1356 128 3 the the DET dti-1356 128 4 patients patient NOUN dti-1356 128 5 with with ADP dti-1356 128 6 diabetes diabetes NOUN dti-1356 128 7 mellitus mellitus NOUN dti-1356 128 8 showed show VERB dti-1356 128 9 antibodies antibody NOUN dti-1356 128 10 against against ADP dti-1356 128 11 the the DET dti-1356 128 12 gnrh gnrh NOUN dti-1356 128 13 receptor receptor NOUN dti-1356 128 14 , , PUNCT dti-1356 128 15 lh lh PROPN dti-1356 128 16 , , PUNCT dti-1356 128 17 or or CCONJ dti-1356 128 18 lh lh PROPN dti-1356 128 19 receptor receptor NOUN dti-1356 128 20 . . PUNCT dti-1356 129 1 the the DET dti-1356 129 2 elisa elisa NOUN dti-1356 129 3 for for ADP dti-1356 129 4 the the DET dti-1356 129 5 analysis analysis NOUN dti-1356 129 6 of of ADP dti-1356 129 7 gnrh2 gnrh2 NOUN dti-1356 129 8 was be AUX dti-1356 129 9 unstable unstable ADJ dti-1356 129 10 , , PUNCT dti-1356 129 11 and and CCONJ dti-1356 129 12 for for ADP dti-1356 129 13 this this DET dti-1356 129 14 reason reason NOUN dti-1356 129 15 these these DET dti-1356 129 16 data datum NOUN dti-1356 129 17 are be AUX dti-1356 129 18 not not PART dti-1356 129 19 shown show VERB dti-1356 129 20 . . PUNCT dti-1356 130 1 the the DET dti-1356 130 2 distribution distribution NOUN dti-1356 130 3 of of ADP dti-1356 130 4 antibodies antibody NOUN dti-1356 130 5 was be AUX dti-1356 130 6 equal equal ADJ dti-1356 130 7 in in ADP dti-1356 130 8 men man NOUN dti-1356 130 9 and and CCONJ dti-1356 130 10 women woman NOUN dti-1356 130 11 among among ADP dti-1356 130 12 controls control NOUN dti-1356 130 13 and and CCONJ dti-1356 130 14 patients patient NOUN dti-1356 130 15 with with ADP dti-1356 130 16 diabetes diabetes NOUN dti-1356 130 17 mellitus mellitus NOUN dti-1356 130 18 . . PUNCT dti-1356 131 1 in in ADP dti-1356 131 2 patients patient NOUN dti-1356 131 3 with with ADP dti-1356 131 4 ibs ibs PROPN dti-1356 131 5 and and CCONJ dti-1356 131 6 dysmotility dysmotility NOUN dti-1356 131 7 , , PUNCT dti-1356 131 8 all all DET dti-1356 131 9 antibodies antibody NOUN dti-1356 131 10 were be AUX dti-1356 131 11 expressed express VERB dti-1356 131 12 in in ADP dti-1356 131 13 women woman NOUN dti-1356 131 14 . . PUNCT dti-1356 132 1 table table NOUN dti-1356 132 2 2 2 NUM dti-1356 132 3 . . PUNCT dti-1356 133 1 the the DET dti-1356 133 2 expression expression NOUN dti-1356 133 3 of of ADP dti-1356 133 4 igm igm PROPN dti-1356 133 5 antibodies antibodie VERB dti-1356 133 6 in in ADP dti-1356 133 7 patients patient NOUN dti-1356 133 8 with with ADP dti-1356 133 9 ibs ibs PROPN dti-1356 133 10 , , PUNCT dti-1356 133 11 dysmotility dysmotility NOUN dti-1356 133 12 , , PUNCT dti-1356 133 13 and/or and/or CCONJ dti-1356 133 14 diabetes diabete VERB dti-1356 133 15 mellitus mellitus NOUN dti-1356 133 16 . . PUNCT dti-1356 134 1 gnrh1 gnrh1 NOUN dti-1356 134 2 n n CCONJ dti-1356 134 3 ( ( PUNCT dti-1356 134 4 % % NOUN dti-1356 134 5 ) ) PUNCT dti-1356 134 6 p p X dti-1356 134 7 - - PUNCT dti-1356 134 8 value value NOUN dti-1356 134 9 progonadoliberin-2 progonadoliberin-2 NUM dti-1356 134 10 n n NOUN dti-1356 134 11 ( ( PUNCT dti-1356 134 12 % % NOUN dti-1356 134 13 ) ) PUNCT dti-1356 134 14 p p X dti-1356 134 15 - - PUNCT dti-1356 134 16 value value NOUN dti-1356 134 17 gnrh gnrh NOUN dti-1356 134 18 receptor receptor NOUN dti-1356 134 19 n n PROPN dti-1356 134 20 ( ( PUNCT dti-1356 134 21 % % NOUN dti-1356 134 22 ) ) PUNCT dti-1356 134 23 p p X dti-1356 134 24 - - PUNCT dti-1356 134 25 value value NOUN dti-1356 134 26 ibs ibs PROPN dti-1356 134 27 / / SYM dti-1356 134 28 dysmotility dysmotility NOUN dti-1356 134 29 ( ( PUNCT dti-1356 134 30 n n NOUN dti-1356 134 31 = = SYM dti-1356 134 32 45 45 NUM dti-1356 134 33 ) ) PUNCT dti-1356 134 34 6 6 NUM dti-1356 134 35 ( ( PUNCT dti-1356 134 36 13 13 NUM dti-1356 134 37 ) ) PUNCT dti-1356 134 38 0.007 0.007 NUM dti-1356 134 39 4 4 NUM dti-1356 134 40 ( ( PUNCT dti-1356 134 41 9 9 NUM dti-1356 134 42 ) ) PUNCT dti-1356 134 43 0.040 0.040 NUM dti-1356 134 44 4 4 NUM dti-1356 134 45 ( ( PUNCT dti-1356 134 46 9 9 NUM dti-1356 134 47 ) ) PUNCT dti-1356 134 48 0.087 0.087 NUM dti-1356 134 49 diabetes diabetes NOUN dti-1356 134 50 mellitus mellitus NOUN dti-1356 134 51 with with ADP dti-1356 134 52 gi gi INTJ dti-1356 134 53 complaints complaint NOUN dti-1356 134 54 ( ( PUNCT dti-1356 134 55 n n NOUN dti-1356 134 56 = = SYM dti-1356 134 57 19 19 NUM dti-1356 134 58 ) ) PUNCT dti-1356 134 59 2 2 NUM dti-1356 134 60 ( ( PUNCT dti-1356 134 61 11 11 NUM dti-1356 134 62 ) ) PUNCT dti-1356 134 63 0.088 0.088 NUM dti-1356 134 64 0 0 NUM dti-1356 134 65 1.000 1.000 NUM dti-1356 134 66 0 0 NUM dti-1356 134 67 1.000 1.000 NUM dti-1356 134 68 consecutive consecutive ADJ dti-1356 134 69 patients patient NOUN dti-1356 134 70 with with ADP dti-1356 134 71 diabetes diabetes NOUN dti-1356 134 72 mellitus mellitus NOUN dti-1356 134 73 ( ( PUNCT dti-1356 134 74 n n NOUN dti-1356 134 75 = = NUM dti-1356 134 76 40 40 NUM dti-1356 134 77 ) ) PUNCT dti-1356 134 78 1 1 NUM dti-1356 134 79 ( ( PUNCT dti-1356 134 80 2 2 NUM dti-1356 134 81 ) ) PUNCT dti-1356 134 82 1.000 1.000 NUM dti-1356 134 83 5 5 NUM dti-1356 134 84 ( ( PUNCT dti-1356 134 85 12 12 NUM dti-1356 134 86 ) ) PUNCT dti-1356 134 87 0.008 0.008 NUM dti-1356 134 88 0 0 NUM dti-1356 134 89 1.000 1.000 NUM dti-1356 134 90 notes note NOUN dti-1356 134 91 : : PUNCT dti-1356 134 92 fischer fischer PROPN dti-1356 134 93 ’s ’s PART dti-1356 134 94 exact exact ADJ dti-1356 134 95 test test NOUN dti-1356 134 96 was be AUX dti-1356 134 97 used use VERB dti-1356 134 98 for for ADP dti-1356 134 99 the the DET dti-1356 134 100 comparisons comparison NOUN dti-1356 134 101 between between ADP dti-1356 134 102 the the DET dti-1356 134 103 prevalence prevalence NOUN dti-1356 134 104 of of ADP dti-1356 134 105 antibodies antibody NOUN dti-1356 134 106 in in ADP dti-1356 134 107 the the DET dti-1356 134 108 different different ADJ dti-1356 134 109 groups group NOUN dti-1356 134 110 and and CCONJ dti-1356 134 111 healthy healthy ADJ dti-1356 134 112 controls control NOUN dti-1356 134 113 . . PUNCT dti-1356 135 1 the the DET dti-1356 135 2 cut cut VERB dti-1356 135 3 - - PUNCT dti-1356 135 4 off off ADP dti-1356 135 5 value value NOUN dti-1356 135 6 to to PART dti-1356 135 7 define define VERB dti-1356 135 8 the the DET dti-1356 135 9 expression expression NOUN dti-1356 135 10 of of ADP dti-1356 135 11 antibodies antibody NOUN dti-1356 135 12 in in ADP dti-1356 135 13 the the DET dti-1356 135 14 healthy healthy ADJ dti-1356 135 15 blood blood NOUN dti-1356 135 16 donors donor NOUN dti-1356 135 17 was be AUX dti-1356 135 18 set set VERB dti-1356 135 19 to to ADP dti-1356 135 20 relative relative ADJ dti-1356 135 21 unit unit NOUN dti-1356 135 22 ( ( PUNCT dti-1356 135 23 ru ru NOUN dti-1356 135 24 ) ) PUNCT dti-1356 135 25 97.5th 97.5th ADJ dti-1356 135 26 percentile percentile ADJ dti-1356 135 27 . . PUNCT dti-1356 136 1 p p X dti-1356 136 2   NOUN dti-1356 136 3 0.05 0.05 NUM dti-1356 136 4 was be AUX dti-1356 136 5 considered consider VERB dti-1356 136 6 as as ADP dti-1356 136 7 statistically statistically ADV dti-1356 136 8 significant significant ADJ dti-1356 136 9 . . PUNCT dti-1356 137 1 abbreviations abbreviation NOUN dti-1356 137 2 : : PUNCT dti-1356 137 3 gi gi NOUN dti-1356 137 4 , , PUNCT dti-1356 137 5 gastrointestinal gastrointestinal ADJ dti-1356 137 6 ; ; PUNCT dti-1356 137 7 gnrh gnrh NOUN dti-1356 137 8 , , PUNCT dti-1356 137 9 gonadotropin gonadotropin NOUN dti-1356 137 10 - - PUNCT dti-1356 137 11 releasing release VERB dti-1356 137 12 hormone hormone NOUN dti-1356 137 13 ; ; PUNCT dti-1356 137 14 n n CCONJ dti-1356 137 15 , , PUNCT dti-1356 137 16 number number NOUN dti-1356 137 17 . . PUNCT dti-1356 138 1 http://www.la-press.com http://www.la-press.com X dti-1356 139 1 http://www.la-press.com/drug-target-insights-journal-j23 http://www.la-press.com/drug-target-insights-journal-j23 VERB dti-1356 139 2 the the DET dti-1356 139 3 expression expression NOUN dti-1356 139 4 of of ADP dti-1356 139 5 serum serum NOUN dti-1356 139 6 antibodies antibody NOUN dti-1356 139 7 against against ADP dti-1356 139 8 gnrh1 gnrh1 NOUN dti-1356 139 9 49drug 49drug NOUN dti-1356 140 1 target target NOUN dti-1356 140 2 insights insight VERB dti-1356 140 3 2014:8 2014:8 NUM dti-1356 140 4 discussion discussion NOUN dti-1356 140 5 the the DET dti-1356 140 6 major major ADJ dti-1356 140 7 finding finding NOUN dti-1356 140 8 in in ADP dti-1356 140 9 our our PRON dti-1356 140 10 present present ADJ dti-1356 140 11 study study NOUN dti-1356 140 12 was be AUX dti-1356 140 13 that that SCONJ dti-1356 140 14 the the DET dti-1356 140 15 expression expression NOUN dti-1356 140 16 in in ADP dti-1356 140 17 serum serum NOUN dti-1356 140 18 of of ADP dti-1356 140 19 igm igm PROPN dti-1356 140 20 antibodies antibody NOUN dti-1356 140 21 against against ADP dti-1356 140 22 gnrh1 gnrh1 NOUN dti-1356 140 23 was be AUX dti-1356 140 24 higher high ADJ dti-1356 140 25 in in ADP dti-1356 140 26 patients patient NOUN dti-1356 140 27 with with ADP dti-1356 140 28 ibs ib NOUN dti-1356 140 29 or or CCONJ dti-1356 140 30 dysmotility dysmotility NOUN dti-1356 140 31 , , PUNCT dti-1356 140 32 and and CCONJ dti-1356 140 33 tended tend VERB dti-1356 140 34 to to PART dti-1356 140 35 be be AUX dti-1356 140 36 higher high ADJ dti-1356 140 37 in in ADP dti-1356 140 38 patients patient NOUN dti-1356 140 39 with with ADP dti-1356 140 40 gastrointestinal gastrointestinal ADJ dti-1356 140 41 complaints complaint NOUN dti-1356 140 42 related relate VERB dti-1356 140 43 to to ADP dti-1356 140 44 diabetes diabetes NOUN dti-1356 140 45 mellitus mellitus NOUN dti-1356 140 46 , , PUNCT dti-1356 140 47 compared compare VERB dti-1356 140 48 to to ADP dti-1356 140 49 controls control NOUN dti-1356 140 50 . . PUNCT dti-1356 141 1 the the DET dti-1356 141 2 prevalence prevalence NOUN dti-1356 141 3 of of ADP dti-1356 141 4 igm igm PROPN dti-1356 141 5 antibodies antibodie VERB dti-1356 141 6 against against ADP dti-1356 141 7 progonadoliberin-2 progonadoliberin-2 NUM dti-1356 141 8 was be AUX dti-1356 141 9 higher high ADJ dti-1356 141 10 in in ADP dti-1356 141 11 patients patient NOUN dti-1356 141 12 with with ADP dti-1356 141 13 ibs ibs PROPN dti-1356 141 14 or or CCONJ dti-1356 141 15 dysmotility dysmotility NOUN dti-1356 141 16 and and CCONJ dti-1356 141 17 in in ADP dti-1356 141 18 consecutive consecutive ADJ dti-1356 141 19 patients patient NOUN dti-1356 141 20 with with ADP dti-1356 141 21 diabetes diabetes NOUN dti-1356 141 22 mellitus mellitus NOUN dti-1356 141 23 , , PUNCT dti-1356 141 24 and and CCONJ dti-1356 141 25 the the DET dti-1356 141 26 prevalence prevalence NOUN dti-1356 141 27 of of ADP dti-1356 141 28 igm igm PROPN dti-1356 141 29 antibodies antibodie VERB dti-1356 141 30 against against ADP dti-1356 141 31 the the DET dti-1356 141 32 gnrh gnrh NOUN dti-1356 141 33 receptor receptor NOUN dti-1356 141 34 tended tend VERB dti-1356 141 35 to to PART dti-1356 141 36 be be AUX dti-1356 141 37 higher high ADJ dti-1356 141 38 in in ADP dti-1356 141 39 patients patient NOUN dti-1356 141 40 with with ADP dti-1356 141 41 ibs ibs PROPN dti-1356 141 42 or or CCONJ dti-1356 141 43 dysmotility dysmotility NOUN dti-1356 141 44 , , PUNCT dti-1356 141 45 compared compare VERB dti-1356 141 46 to to ADP dti-1356 141 47 controls control NOUN dti-1356 141 48 . . PUNCT dti-1356 142 1 although although SCONJ dti-1356 142 2 these these DET dti-1356 142 3 three three NUM dti-1356 142 4 diseases disease NOUN dti-1356 142 5 are be AUX dti-1356 142 6 classified classify VERB dti-1356 142 7 as as ADP dti-1356 142 8 different different ADJ dti-1356 142 9 entities entity NOUN dti-1356 142 10 , , PUNCT dti-1356 142 11 they they PRON dti-1356 142 12 have have VERB dti-1356 142 13 gastrointestinal gastrointestinal ADJ dti-1356 142 14 pain pain NOUN dti-1356 142 15 and and CCONJ dti-1356 142 16 dysfunction dysfunction NOUN dti-1356 142 17 in in ADP dti-1356 142 18 common common ADJ dti-1356 142 19 . . PUNCT dti-1356 143 1 the the DET dti-1356 143 2 difference difference NOUN dti-1356 143 3 in in ADP dti-1356 143 4 antibody antibody NOUN dti-1356 143 5 prevalence prevalence NOUN dti-1356 143 6 between between ADP dti-1356 143 7 the the DET dti-1356 143 8 two two NUM dti-1356 143 9 diabetes diabetes NOUN dti-1356 143 10 cohorts cohort NOUN dti-1356 143 11 may may AUX dti-1356 143 12 be be AUX dti-1356 143 13 because because SCONJ dti-1356 143 14 of of ADP dti-1356 143 15 the the DET dti-1356 143 16 fact fact NOUN dti-1356 143 17 that that SCONJ dti-1356 143 18 the the DET dti-1356 143 19 patients patient NOUN dti-1356 143 20 with with ADP dti-1356 143 21 gastrointestinal gastrointestinal ADJ dti-1356 143 22 complaints complaint NOUN dti-1356 143 23 had have AUX dti-1356 143 24 a a DET dti-1356 143 25 more more ADV dti-1356 143 26 severe severe ADJ dti-1356 143 27 gastrointestinal gastrointestinal ADJ dti-1356 143 28 disorder disorder NOUN dti-1356 143 29 with with ADP dti-1356 143 30 gastroparesis gastroparesis NOUN dti-1356 143 31 in in ADP dti-1356 143 32 53 53 NUM dti-1356 143 33 % % NOUN dti-1356 143 34 of of ADP dti-1356 143 35 the the DET dti-1356 143 36 patients patient NOUN dti-1356 143 37 , , PUNCT dti-1356 143 38 compared compare VERB dti-1356 143 39 to to ADP dti-1356 143 40 20 20 NUM dti-1356 143 41 % % NOUN dti-1356 143 42 in in ADP dti-1356 143 43 consecutive consecutive ADJ dti-1356 143 44 diabetes diabetes NOUN dti-1356 143 45 patients patient NOUN dti-1356 143 46 , , PUNCT dti-1356 143 47 and and CCONJ dti-1356 143 48 a a DET dti-1356 143 49 higher high ADJ dti-1356 143 50 prevalence prevalence NOUN dti-1356 143 51 of of ADP dti-1356 143 52 gastrointestinal gastrointestinal ADJ dti-1356 143 53 symptoms symptom NOUN dti-1356 143 54 . . PUNCT dti-1356 144 1 the the DET dti-1356 144 2 present present ADJ dti-1356 144 3 study study NOUN dti-1356 144 4 confirms confirm VERB dti-1356 144 5 previous previous ADJ dti-1356 144 6 results result NOUN dti-1356 144 7 that that PRON dti-1356 144 8 igm igm PROPN dti-1356 144 9 antibodies antibodie VERB dti-1356 144 10 against against ADP dti-1356 144 11 gnrh1 gnrh1 NOUN dti-1356 144 12 and and CCONJ dti-1356 144 13 gnrh gnrh NOUN dti-1356 144 14 receptors receptor NOUN dti-1356 144 15 are be AUX dti-1356 144 16 present present ADJ dti-1356 144 17 in in ADP dti-1356 144 18 a a DET dti-1356 144 19 subgroup subgroup NOUN dti-1356 144 20 of of ADP dti-1356 144 21 patients patient NOUN dti-1356 144 22 suffering suffer VERB dti-1356 144 23 from from ADP dti-1356 144 24 functional functional ADJ dti-1356 144 25 disorders disorder NOUN dti-1356 144 26 and and CCONJ dti-1356 144 27 dysmotility,3,12,14 dysmotility,3,12,14 ADV dti-1356 144 28 as as ADV dti-1356 144 29 well well ADV dti-1356 144 30 as as ADP dti-1356 144 31 in in ADP dti-1356 144 32 patients patient NOUN dti-1356 144 33 with with ADP dti-1356 144 34 diabetes diabete NOUN dti-1356 144 35 mellitus.12,13 mellitus.12,13 VERB dti-1356 144 36 in in ADP dti-1356 144 37 the the DET dti-1356 144 38 present present ADJ dti-1356 144 39 elisa elisa NOUN dti-1356 144 40 , , PUNCT dti-1356 144 41 a a DET dti-1356 144 42 titer titer NOUN dti-1356 144 43 above above ADP dti-1356 144 44 the the DET dti-1356 144 45 97.5th 97.5th ADJ dti-1356 144 46 percentile percentile NOUN dti-1356 144 47 of of ADP dti-1356 144 48 the the DET dti-1356 144 49 standard standard ADJ dti-1356 144 50 curves curve NOUN dti-1356 144 51 in in ADP dti-1356 144 52 controls control NOUN dti-1356 144 53 was be AUX dti-1356 144 54 considered consider VERB dti-1356 144 55 positive positive ADJ dti-1356 144 56 . . PUNCT dti-1356 145 1 in in ADP dti-1356 145 2 the the DET dti-1356 145 3 former former ADJ dti-1356 145 4 elisa elisa NOUN dti-1356 145 5 , , PUNCT dti-1356 145 6 we we PRON dti-1356 145 7 classified classify VERB dti-1356 145 8 all all DET dti-1356 145 9 antibody antibody NOUN dti-1356 145 10 levels level NOUN dti-1356 145 11 above above ADP dti-1356 145 12 0 0 NUM dti-1356 145 13 in in ADP dti-1356 145 14 absorbance absorbance NOUN dti-1356 145 15 , , PUNCT dti-1356 145 16 after after ADP dti-1356 145 17 subtraction subtraction NOUN dti-1356 145 18 of of ADP dti-1356 145 19 background background NOUN dti-1356 145 20 levels level NOUN dti-1356 145 21 , , PUNCT dti-1356 145 22 as as ADV dti-1356 145 23 positive positive ADJ dti-1356 145 24 , , PUNCT dti-1356 145 25 and and CCONJ dti-1356 145 26 therefore therefore ADV dti-1356 145 27 the the DET dti-1356 145 28 prevalence prevalence NOUN dti-1356 145 29 was be AUX dti-1356 145 30 lower low ADJ dti-1356 145 31 in in ADP dti-1356 145 32 both both DET dti-1356 145 33 controls control NOUN dti-1356 145 34 and and CCONJ dti-1356 145 35 patients.3,12,13 patients.3,12,13 NOUN dti-1356 145 36 we we PRON dti-1356 145 37 have have AUX dti-1356 145 38 previously previously ADV dti-1356 145 39 reported report VERB dti-1356 145 40 gastrointestinal gastrointestinal ADJ dti-1356 145 41 complications complication NOUN dti-1356 145 42 and and CCONJ dti-1356 145 43 expression expression NOUN dti-1356 145 44 of of ADP dti-1356 145 45 gnrh gnrh NOUN dti-1356 145 46 antibodies antibodie VERB dti-1356 145 47 in in ADP dti-1356 145 48 serum serum NOUN dti-1356 145 49 and and CCONJ dti-1356 145 50 a a DET dti-1356 145 51 reduced reduced ADJ dti-1356 145 52 number number NOUN dti-1356 145 53 of of ADP dti-1356 145 54 gnrh gnrh NOUN dti-1356 145 55 - - PUNCT dti-1356 145 56 containing contain VERB dti-1356 145 57 enteric enteric ADJ dti-1356 145 58 neurons neuron NOUN dti-1356 145 59 in in ADP dti-1356 145 60 patients patient NOUN dti-1356 145 61 after after ADP dti-1356 145 62 treatment treatment NOUN dti-1356 145 63 with with ADP dti-1356 145 64 gnrh gnrh NOUN dti-1356 145 65 analogs.5,6,27 analogs.5,6,27 PROPN dti-1356 145 66 however however ADV dti-1356 145 67 , , PUNCT dti-1356 145 68 the the DET dti-1356 145 69 patients patient NOUN dti-1356 145 70 who who PRON dti-1356 145 71 expressed express VERB dti-1356 145 72 antibodies antibody NOUN dti-1356 145 73 against against ADP dti-1356 145 74 gnrh1 gnrh1 NOUN dti-1356 145 75 in in ADP dti-1356 145 76 the the DET dti-1356 145 77 present present ADJ dti-1356 145 78 study study NOUN dti-1356 145 79 cohort cohort NOUN dti-1356 145 80 have have AUX dti-1356 145 81 not not PART dti-1356 145 82 been be AUX dti-1356 145 83 treated treat VERB dti-1356 145 84 by by ADP dti-1356 145 85 any any DET dti-1356 145 86 gnrh gnrh NOUN dti-1356 145 87 analogs analog NOUN dti-1356 145 88 . . PUNCT dti-1356 146 1 both both DET dti-1356 146 2 gnrh1 gnrh1 NOUN dti-1356 146 3 and and CCONJ dti-1356 146 4 gnrh2 gnrh2 NOUN dti-1356 146 5 are be AUX dti-1356 146 6 expressed express VERB dti-1356 146 7 in in ADP dti-1356 146 8 enteric enteric ADJ dti-1356 146 9 neurons neuron NOUN dti-1356 146 10 of of ADP dti-1356 146 11 the the DET dti-1356 146 12 human human ADJ dti-1356 146 13 ens.5,6,8,27 ens.5,6,8,27 PROPN dti-1356 146 14 the the DET dti-1356 146 15 antibodies antibody NOUN dti-1356 146 16 may may AUX dti-1356 146 17 represent represent VERB dti-1356 146 18 a a DET dti-1356 146 19 primary primary ADJ dti-1356 146 20 , , PUNCT dti-1356 146 21 autoimmune autoimmune ADJ dti-1356 146 22 disease disease NOUN dti-1356 146 23 rendering render VERB dti-1356 146 24 neuronal neuronal ADJ dti-1356 146 25 damage damage NOUN dti-1356 146 26 and and CCONJ dti-1356 146 27 gastrointestinal gastrointestinal ADJ dti-1356 146 28 complaints complaint NOUN dti-1356 146 29 . . PUNCT dti-1356 147 1 another another DET dti-1356 147 2 possibility possibility NOUN dti-1356 147 3 is be AUX dti-1356 147 4 that that SCONJ dti-1356 147 5 the the DET dti-1356 147 6 antibodies antibody NOUN dti-1356 147 7 are be AUX dti-1356 147 8 secondary secondary ADJ dti-1356 147 9 to to ADP dti-1356 147 10 all all DET dti-1356 147 11 kinds kind NOUN dti-1356 147 12 of of ADP dti-1356 147 13 damage damage NOUN dti-1356 147 14 of of ADP dti-1356 147 15 the the DET dti-1356 147 16 ens en NOUN dti-1356 147 17 exposing expose VERB dti-1356 147 18 gnrh gnrh NOUN dti-1356 147 19 to to ADP dti-1356 147 20 immune immune NOUN dti-1356 147 21 - - PUNCT dti-1356 147 22 reactive reactive NOUN dti-1356 147 23 cells.28 cells.28 NOUN dti-1356 147 24 our our PRON dti-1356 147 25 hypothesis hypothesis NOUN dti-1356 147 26 is be AUX dti-1356 147 27 , , PUNCT dti-1356 147 28 taking take VERB dti-1356 147 29 all all DET dti-1356 147 30 studies study NOUN dti-1356 147 31 in in ADP dti-1356 147 32 this this DET dti-1356 147 33 field field NOUN dti-1356 147 34 into into ADP dti-1356 147 35 consideration,3,5,6,12–14,16,27,29 consideration,3,5,6,12–14,16,27,29 NOUN dti-1356 147 36 that that PRON dti-1356 147 37 the the DET dti-1356 147 38 antibodies antibody NOUN dti-1356 147 39 are be AUX dti-1356 147 40 secondary secondary ADJ dti-1356 147 41 to to ADP dti-1356 147 42 the the DET dti-1356 147 43 neuronal neuronal ADJ dti-1356 147 44 damage damage NOUN dti-1356 147 45 in in ADP dti-1356 147 46 a a DET dti-1356 147 47 subgroup subgroup NOUN dti-1356 147 48 of of ADP dti-1356 147 49 patients patient NOUN dti-1356 147 50 , , PUNCT dti-1356 147 51 and and CCONJ dti-1356 147 52 not not PART dti-1356 147 53 causal causal ADV dti-1356 147 54 . . PUNCT dti-1356 148 1 full full ADJ dti-1356 148 2 - - PUNCT dti-1356 148 3 thickness thickness NOUN dti-1356 148 4 biopsies biopsy NOUN dti-1356 148 5 are be AUX dti-1356 148 6 not not PART dti-1356 148 7 considered consider VERB dti-1356 148 8 in in ADP dti-1356 148 9 patients patient NOUN dti-1356 148 10 with with ADP dti-1356 148 11 ibs ibs PROPN dti-1356 148 12 . . PUNCT dti-1356 149 1 thus thus ADV dti-1356 149 2 , , PUNCT dti-1356 149 3 we we PRON dti-1356 149 4 can can AUX dti-1356 149 5 not not PART dti-1356 149 6 examine examine VERB dti-1356 149 7 the the DET dti-1356 149 8 expression expression NOUN dti-1356 149 9 of of ADP dti-1356 149 10 gnrh gnrh NOUN dti-1356 149 11 in in ADP dti-1356 149 12 the the DET dti-1356 149 13 bowel bowel NOUN dti-1356 149 14 wall wall NOUN dti-1356 149 15 in in ADP dti-1356 149 16 these these DET dti-1356 149 17 patients patient NOUN dti-1356 149 18 . . PUNCT dti-1356 150 1 however however ADV dti-1356 150 2 , , PUNCT dti-1356 150 3 as as SCONJ dti-1356 150 4 gnrh gnrh NOUN dti-1356 150 5 is be AUX dti-1356 150 6 expressed express VERB dti-1356 150 7 in in ADP dti-1356 150 8 enteric enteric ADJ dti-1356 150 9 neurons neuron NOUN dti-1356 150 10 , , PUNCT dti-1356 150 11 and and CCONJ dti-1356 150 12 the the DET dti-1356 150 13 number number NOUN dti-1356 150 14 of of ADP dti-1356 150 15 gnrh gnrh NOUN dti-1356 150 16 - - PUNCT dti-1356 150 17 containing contain VERB dti-1356 150 18 enteric enteric ADJ dti-1356 150 19 neurons neuron NOUN dti-1356 150 20 is be AUX dti-1356 150 21 reduced reduce VERB dti-1356 150 22 in in ADP dti-1356 150 23 patients patient NOUN dti-1356 150 24 suffering suffer VERB dti-1356 150 25 from from ADP dti-1356 150 26 dysmotility dysmotility NOUN dti-1356 150 27 with with ADP dti-1356 150 28 serum serum NOUN dti-1356 150 29 antibodies antibody NOUN dti-1356 150 30 against against ADP dti-1356 150 31 gnrh gnrh NOUN dti-1356 150 32 and and CCONJ dti-1356 150 33 progonadoliberin-2,5,6,8,27 progonadoliberin-2,5,6,8,27 INTJ dti-1356 150 34 we we PRON dti-1356 150 35 postulate postulate VERB dti-1356 150 36 that that SCONJ dti-1356 150 37 neuronal neuronal ADJ dti-1356 150 38 damage damage NOUN dti-1356 150 39 exposes expose VERB dti-1356 150 40 gnrh gnrh NOUN dti-1356 150 41 and and CCONJ dti-1356 150 42 progonadoliberin-2 progonadoliberin-2 NUM dti-1356 150 43 to to ADP dti-1356 150 44 immune immune NOUN dti-1356 150 45 - - PUNCT dti-1356 150 46 presenting present VERB dti-1356 150 47 cells cell NOUN dti-1356 150 48 , , PUNCT dti-1356 150 49 resulting result VERB dti-1356 150 50 in in ADP dti-1356 150 51 antibody antibody NOUN dti-1356 150 52 formation formation NOUN dti-1356 150 53 . . PUNCT dti-1356 151 1 the the DET dti-1356 151 2 antibodies antibody NOUN dti-1356 151 3 could could AUX dti-1356 151 4 thus thus ADV dti-1356 151 5 be be AUX dti-1356 151 6 markers marker NOUN dti-1356 151 7 of of ADP dti-1356 151 8 enteric enteric ADJ dti-1356 151 9 neuron neuron NOUN dti-1356 151 10 damage damage NOUN dti-1356 151 11 . . PUNCT dti-1356 152 1 we we PRON dti-1356 152 2 know know VERB dti-1356 152 3 from from ADP dti-1356 152 4 animal animal NOUN dti-1356 152 5 trials trial NOUN dti-1356 152 6 that that SCONJ dti-1356 152 7 in in ADP dti-1356 152 8 spite spite NOUN dti-1356 152 9 of of ADP dti-1356 152 10 a a DET dti-1356 152 11 marked mark VERB dti-1356 152 12 loss loss NOUN dti-1356 152 13 of of ADP dti-1356 152 14 50 50 NUM dti-1356 152 15 % % NOUN dti-1356 152 16 of of ADP dti-1356 152 17 enteric enteric ADJ dti-1356 152 18 neurons neuron NOUN dti-1356 152 19 after after ADP dti-1356 152 20 treatment treatment NOUN dti-1356 152 21 with with ADP dti-1356 152 22 the the DET dti-1356 152 23 gnrh gnrh NOUN dti-1356 152 24 analog analog NOUN dti-1356 152 25 buserelin buserelin PROPN dti-1356 152 26 , , PUNCT dti-1356 152 27 the the DET dti-1356 152 28 gastrointestinal gastrointestinal ADJ dti-1356 152 29 function function NOUN dti-1356 152 30 is be AUX dti-1356 152 31 well well ADV dti-1356 152 32 preserved preserve VERB dti-1356 152 33 with with ADP dti-1356 152 34 unaffected unaffected ADJ dti-1356 152 35 weight weight NOUN dti-1356 152 36 and and CCONJ dti-1356 152 37 healthy healthy ADJ dti-1356 152 38 rats.29 rats.29 NOUN dti-1356 152 39 thus thus ADV dti-1356 152 40 , , PUNCT dti-1356 152 41 a a DET dti-1356 152 42 subgroup subgroup NOUN dti-1356 152 43 of of ADP dti-1356 152 44 ibs ibs PROPN dti-1356 152 45 patients patient NOUN dti-1356 152 46 may may AUX dti-1356 152 47 have have VERB dti-1356 152 48 enteric enteric NOUN dti-1356 152 49 neuropathy neuropathy ADJ dti-1356 152 50 , , PUNCT dti-1356 152 51 which which PRON dti-1356 152 52 remains remain VERB dti-1356 152 53 undiscovered undiscovered ADJ dti-1356 152 54 by by ADP dti-1356 152 55 non non ADJ dti-1356 152 56 - - ADJ dti-1356 152 57 sensitive sensitive ADJ dti-1356 152 58 , , PUNCT dti-1356 152 59 clinical clinical ADJ dti-1356 152 60 examinations examination NOUN dti-1356 152 61 . . PUNCT dti-1356 153 1 furthermore furthermore ADV dti-1356 153 2 , , PUNCT dti-1356 153 3 we we PRON dti-1356 153 4 know know VERB dti-1356 153 5 neither neither CCONJ dti-1356 153 6 the the DET dti-1356 153 7 time time NOUN dti-1356 153 8 relation relation NOUN dti-1356 153 9 in in ADP dti-1356 153 10 the the DET dti-1356 153 11 development development NOUN dti-1356 153 12 of of ADP dti-1356 153 13 symptomatology symptomatology NOUN dti-1356 153 14 and and CCONJ dti-1356 153 15 antibodies antibodie VERB dti-1356 153 16 nor nor CCONJ dti-1356 153 17 the the DET dti-1356 153 18 difference difference NOUN dti-1356 153 19 between between ADP dti-1356 153 20 the the DET dti-1356 153 21 formation formation NOUN dti-1356 153 22 of of ADP dti-1356 153 23 antibodies antibody NOUN dti-1356 153 24 against against ADP dti-1356 153 25 gnrh1 gnrh1 NOUN dti-1356 153 26 and and CCONJ dti-1356 153 27 progonadoliberin-2 progonadoliberin-2 NUM dti-1356 153 28 . . PUNCT dti-1356 154 1 it it PRON dti-1356 154 2 could could AUX dti-1356 154 3 possibly possibly ADV dti-1356 154 4 reflect reflect VERB dti-1356 154 5 a a DET dti-1356 154 6 difference difference NOUN dti-1356 154 7 in in ADP dti-1356 154 8 time time NOUN dti-1356 154 9 , , PUNCT dti-1356 154 10 one one NUM dti-1356 154 11 antibody antibody NOUN dti-1356 154 12 appearing appear VERB dti-1356 154 13 early early ADV dti-1356 154 14 in in ADP dti-1356 154 15 the the DET dti-1356 154 16 disease disease NOUN dti-1356 154 17 process process NOUN dti-1356 154 18 and and CCONJ dti-1356 154 19 one one NUM dti-1356 154 20 appearing appear VERB dti-1356 154 21 later later ADV dti-1356 154 22 . . PUNCT dti-1356 155 1 all all DET dti-1356 155 2 blood blood NOUN dti-1356 155 3 samples sample NOUN dti-1356 155 4 were be AUX dti-1356 155 5 collected collect VERB dti-1356 155 6 several several ADJ dti-1356 155 7 years year NOUN dti-1356 155 8 after after ADP dti-1356 155 9 the the DET dti-1356 155 10 debut debut NOUN dti-1356 155 11 of of ADP dti-1356 155 12 gastrointestinal gastrointestinal ADJ dti-1356 155 13 complaints complaint NOUN dti-1356 155 14 , , PUNCT dti-1356 155 15 which which PRON dti-1356 155 16 can can AUX dti-1356 155 17 influence influence VERB dti-1356 155 18 the the DET dti-1356 155 19 results result NOUN dti-1356 155 20 , , PUNCT dti-1356 155 21 as as SCONJ dti-1356 155 22 the the DET dti-1356 155 23 titer titer NOUN dti-1356 155 24 declines decline VERB dti-1356 155 25 with with ADP dti-1356 155 26 time.5 time.5 NOUN dti-1356 155 27 no no DET dti-1356 155 28 organic organic ADJ dti-1356 155 29 changes change NOUN dti-1356 155 30 exist exist VERB dti-1356 155 31 that that PRON dti-1356 155 32 are be AUX dti-1356 155 33 pathognomonic pathognomonic ADJ dti-1356 155 34 for for ADP dti-1356 155 35 ibs ib NOUN dti-1356 155 36 , , PUNCT dti-1356 155 37 although although SCONJ dti-1356 155 38 inflammatory inflammatory ADJ dti-1356 155 39 mediators mediator NOUN dti-1356 155 40 have have AUX dti-1356 155 41 been be AUX dti-1356 155 42 discussed discuss VERB dti-1356 155 43 in in ADP dti-1356 155 44 recent recent ADJ dti-1356 155 45 years,30 years,30 NOUN dti-1356 155 46 and and CCONJ dti-1356 155 47 active active ADJ dti-1356 155 48 immune immune ADJ dti-1356 155 49 responses response NOUN dti-1356 155 50 have have AUX dti-1356 155 51 been be AUX dti-1356 155 52 found find VERB dti-1356 155 53 in in ADP dti-1356 155 54 subpopulations subpopulation NOUN dti-1356 155 55 of of ADP dti-1356 155 56 ibs ibs PROPN dti-1356 155 57 patients.31 patients.31 NOUN dti-1356 155 58 antibodies antibodie VERB dti-1356 155 59 against against ADP dti-1356 155 60 gnrh gnrh NOUN dti-1356 155 61 and and CCONJ dti-1356 155 62 its its PRON dti-1356 155 63 receptor receptor NOUN dti-1356 155 64 are be AUX dti-1356 155 65 the the DET dti-1356 155 66 first first ADJ dti-1356 155 67 specific specific ADJ dti-1356 155 68 , , PUNCT dti-1356 155 69 organic organic ADJ dti-1356 155 70 parameter parameter NOUN dti-1356 155 71 found find VERB dti-1356 155 72 so so ADV dti-1356 155 73 far far ADV dti-1356 155 74 , , PUNCT dti-1356 155 75 and and CCONJ dti-1356 155 76 could could AUX dti-1356 155 77 represent represent VERB dti-1356 155 78 a a DET dti-1356 155 79 subpopulation subpopulation NOUN dti-1356 155 80 of of ADP dti-1356 155 81 ibs ibs PROPN dti-1356 155 82 . . PUNCT dti-1356 156 1 that that SCONJ dti-1356 156 2 only only ADJ dti-1356 156 3 female female ADJ dti-1356 156 4 patients patient NOUN dti-1356 156 5 with with ADP dti-1356 156 6 ibs ibs PROPN dti-1356 156 7 and and CCONJ dti-1356 156 8 dysmotility dysmotility NOUN dti-1356 156 9 expressed express VERB dti-1356 156 10 antibodies antibody NOUN dti-1356 156 11 may may AUX dti-1356 156 12 depend depend VERB dti-1356 156 13 on on ADP dti-1356 156 14 the the DET dti-1356 156 15 female female ADJ dti-1356 156 16 predominance predominance NOUN dti-1356 156 17 in in ADP dti-1356 156 18 this this DET dti-1356 156 19 group group NOUN dti-1356 156 20 , , PUNCT dti-1356 156 21 and and CCONJ dti-1356 156 22 does do AUX dti-1356 156 23 not not PART dti-1356 156 24 exclude exclude VERB dti-1356 156 25 the the DET dti-1356 156 26 possibility possibility NOUN dti-1356 156 27 that that SCONJ dti-1356 156 28 male male ADJ dti-1356 156 29 patients patient NOUN dti-1356 156 30 may may AUX dti-1356 156 31 express express VERB dti-1356 156 32 antibodies antibody NOUN dti-1356 156 33 as as ADV dti-1356 156 34 well well ADV dti-1356 156 35 . . PUNCT dti-1356 157 1 ibs ibs PROPN dti-1356 157 2 is be AUX dti-1356 157 3 associated associate VERB dti-1356 157 4 with with ADP dti-1356 157 5 affective affective ADJ dti-1356 157 6 disturbances disturbance NOUN dti-1356 157 7 and and CCONJ dti-1356 157 8 psychiatric psychiatric ADJ dti-1356 157 9 disorders.4 disorders.4 PROPN dti-1356 157 10 functional functional ADJ dti-1356 157 11 magnetic magnetic ADJ dti-1356 157 12 resonance resonance NOUN dti-1356 157 13 imaging imaging NOUN dti-1356 157 14 ( ( PUNCT dti-1356 157 15 fmri fmri ADJ dti-1356 157 16 ) ) PUNCT dti-1356 157 17 reveals reveal VERB dti-1356 157 18 significant significant ADJ dti-1356 157 19 differences difference NOUN dti-1356 157 20 in in ADP dti-1356 157 21 the the DET dti-1356 157 22 neural neural ADJ dti-1356 157 23 processing processing NOUN dti-1356 157 24 of of ADP dti-1356 157 25 pain pain NOUN dti-1356 157 26 between between ADP dti-1356 157 27 ibs ibs PROPN dti-1356 157 28 patients patient NOUN dti-1356 157 29 and and CCONJ dti-1356 157 30 controls control NOUN dti-1356 157 31 , , PUNCT dti-1356 157 32 further far ADV dti-1356 157 33 underlining underline VERB dti-1356 157 34 the the DET dti-1356 157 35 importance importance NOUN dti-1356 157 36 of of ADP dti-1356 157 37 central central ADJ dti-1356 157 38 mechanisms mechanism NOUN dti-1356 157 39 in in ADP dti-1356 157 40 the the DET dti-1356 157 41 pathophysiology pathophysiology NOUN dti-1356 157 42 of of ADP dti-1356 157 43 visceral visceral ADJ dti-1356 157 44 hypersensitivity hypersensitivity NOUN dti-1356 157 45 in in ADP dti-1356 157 46 these these DET dti-1356 157 47 patients.32,33 patients.32,33 NOUN dti-1356 158 1 both both PRON dti-1356 158 2 diabetes diabete VERB dti-1356 158 3 mellitus mellitus NOUN dti-1356 158 4 and and CCONJ dti-1356 158 5 primary primary ADJ dti-1356 158 6 sjögren sjögren PROPN dti-1356 158 7 ’s ’s PART dti-1356 158 8 syndrome syndrome NOUN dti-1356 158 9 are be AUX dti-1356 158 10 associated associate VERB dti-1356 158 11 with with ADP dti-1356 158 12 autonomic autonomic ADJ dti-1356 158 13 neuropathy neuropathy ADJ dti-1356 158 14 and and CCONJ dti-1356 158 15 gastrointestinal gastrointestinal ADJ dti-1356 158 16 complaints.2,14,25,26 complaints.2,14,25,26 NOUN dti-1356 158 17 since since SCONJ dti-1356 158 18 gnrh1 gnrh1 NOUN dti-1356 158 19 and and CCONJ dti-1356 158 20 gnrh2 gnrh2 NOUN dti-1356 158 21 are be AUX dti-1356 158 22 found find VERB dti-1356 158 23 in in ADP dti-1356 158 24 both both CCONJ dti-1356 158 25 the the DET dti-1356 158 26 central central ADJ dti-1356 158 27 and and CCONJ dti-1356 158 28 peripheral peripheral ADJ dti-1356 158 29 nervous nervous ADJ dti-1356 158 30 systems,8,17,34 systems,8,17,34 NOUN dti-1356 158 31 we we PRON dti-1356 158 32 do do AUX dti-1356 158 33 not not PART dti-1356 158 34 know know VERB dti-1356 158 35 whether whether SCONJ dti-1356 158 36 the the DET dti-1356 158 37 antibody antibody NOUN dti-1356 158 38 formation formation NOUN dti-1356 158 39 originates originate NOUN dti-1356 158 40 from from ADP dti-1356 158 41 a a DET dti-1356 158 42 central central ADJ dti-1356 158 43 or or CCONJ dti-1356 158 44 a a DET dti-1356 158 45 peripheral peripheral ADJ dti-1356 158 46 neural neural ADJ dti-1356 158 47 injury injury NOUN dti-1356 158 48 . . PUNCT dti-1356 159 1 the the DET dti-1356 159 2 association association NOUN dti-1356 159 3 between between ADP dti-1356 159 4 autonomic autonomic ADJ dti-1356 159 5 neuropathy neuropathy ADJ dti-1356 159 6 and and CCONJ dti-1356 159 7 lowered lower VERB dti-1356 159 8 body body NOUN dti-1356 159 9 mass mass NOUN dti-1356 159 10 index index NOUN dti-1356 159 11 ( ( PUNCT dti-1356 159 12 bmi bmi PROPN dti-1356 159 13 ) ) PUNCT dti-1356 159 14 , , PUNCT dti-1356 159 15 and and CCONJ dti-1356 159 16 the the DET dti-1356 159 17 occurrence occurrence NOUN dti-1356 159 18 of of ADP dti-1356 159 19 gnrh gnrh NOUN dti-1356 159 20 antibodies antibodie VERB dti-1356 159 21 in in ADP dti-1356 159 22 the the DET dti-1356 159 23 initial initial ADJ dti-1356 159 24 elisa,13 elisa,13 NOUN dti-1356 159 25 could could AUX dti-1356 159 26 not not PART dti-1356 159 27 be be AUX dti-1356 159 28 confirmed confirm VERB dti-1356 159 29 . . PUNCT dti-1356 160 1 the the DET dti-1356 160 2 present present ADJ dti-1356 160 3 and and CCONJ dti-1356 160 4 former former ADJ dti-1356 160 5 small small ADJ dti-1356 160 6 studies study NOUN dti-1356 160 7 do do AUX dti-1356 160 8 not not PART dti-1356 160 9 allow allow VERB dti-1356 160 10 a a DET dti-1356 160 11 search search NOUN dti-1356 160 12 for for ADP dti-1356 160 13 clinical clinical ADJ dti-1356 160 14 associations association NOUN dti-1356 160 15 with with ADP dti-1356 160 16 the the DET dti-1356 160 17 antibody antibody NOUN dti-1356 160 18 occurrence.3,14 occurrence.3,14 NOUN dti-1356 160 19 the the DET dti-1356 160 20 effect effect NOUN dti-1356 160 21 of of ADP dti-1356 160 22 gnrh gnrh NOUN dti-1356 160 23 and and CCONJ dti-1356 160 24 lh lh PROPN dti-1356 160 25 on on ADP dti-1356 160 26 the the DET dti-1356 160 27 ens ens NOUN dti-1356 160 28 is be AUX dti-1356 160 29 not not PART dti-1356 160 30 thoroughly thoroughly ADV dti-1356 160 31 evaluated evaluate VERB dti-1356 160 32 , , PUNCT dti-1356 160 33 but but CCONJ dti-1356 160 34 seems seem VERB dti-1356 160 35 to to PART dti-1356 160 36 affect affect VERB dti-1356 160 37 motility motility NOUN dti-1356 160 38 and and CCONJ dti-1356 160 39 secretion.9–11,35 secretion.9–11,35 NOUN dti-1356 160 40 no no DET dti-1356 160 41 patient patient NOUN dti-1356 160 42 with with ADP dti-1356 160 43 diabetes diabetes NOUN dti-1356 160 44 mellitus mellitus NOUN dti-1356 160 45 in in ADP dti-1356 160 46 the the DET dti-1356 160 47 present present ADJ dti-1356 160 48 study study NOUN dti-1356 160 49 , , PUNCT dti-1356 160 50 or or CCONJ dti-1356 160 51 primary primary ADJ dti-1356 160 52 sjögren sjögren PROPN dti-1356 160 53 ’s ’s PART dti-1356 160 54 syndrome syndrome NOUN dti-1356 160 55 in in ADP dti-1356 160 56 a a DET dti-1356 160 57 previous previous ADJ dti-1356 160 58 study,14 study,14 ADV dti-1356 160 59 expressed express VERB dti-1356 160 60 antibodies antibody NOUN dti-1356 160 61 against against ADP dti-1356 160 62 lh lh PROPN dti-1356 160 63 or or CCONJ dti-1356 160 64 its its PRON dti-1356 160 65 receptor receptor NOUN dti-1356 160 66 , , PUNCT dti-1356 160 67 as as SCONJ dti-1356 160 68 has have AUX dti-1356 160 69 previously previously ADV dti-1356 160 70 been be AUX dti-1356 160 71 described describe VERB dti-1356 160 72 in in ADP dti-1356 160 73 patients patient NOUN dti-1356 160 74 with with ADP dti-1356 160 75 infertility.16 infertility.16 PROPN dti-1356 160 76 autoantibodies autoantibody NOUN dti-1356 160 77 against against ADP dti-1356 160 78 folliclestimulating folliclestimulating NOUN dti-1356 160 79 hormone hormone NOUN dti-1356 160 80 ( ( PUNCT dti-1356 160 81 fsh fsh NOUN dti-1356 160 82 ) ) PUNCT dti-1356 160 83 , , PUNCT dti-1356 160 84 lh lh PROPN dti-1356 160 85 , , PUNCT dti-1356 160 86 and and CCONJ dti-1356 160 87 ovarian ovarian ADJ dti-1356 160 88 factors factor NOUN dti-1356 160 89 have have AUX dti-1356 160 90 also also ADV dti-1356 160 91 been be AUX dti-1356 160 92 found find VERB dti-1356 160 93 by by ADP dti-1356 160 94 others other NOUN dti-1356 160 95 in in ADP dti-1356 160 96 infertile infertile ADJ dti-1356 160 97 women woman NOUN dti-1356 160 98 , , PUNCT dti-1356 160 99 and and CCONJ dti-1356 160 100 could could AUX dti-1356 160 101 indicate indicate VERB dti-1356 160 102 an an DET dti-1356 160 103 autoimmune autoimmune ADJ dti-1356 160 104 disorder disorder NOUN dti-1356 160 105 targeting target VERB dti-1356 160 106 the the DET dti-1356 160 107 ovary.36 ovary.36 NOUN dti-1356 160 108 this this PRON dti-1356 160 109 suggests suggest VERB dti-1356 160 110 that that SCONJ dti-1356 160 111 antibodies antibodie VERB dti-1356 160 112 against against ADP dti-1356 160 113 lh lh PROPN dti-1356 160 114 or or CCONJ dti-1356 160 115 its its PRON dti-1356 160 116 receptor receptor NOUN dti-1356 160 117 are be AUX dti-1356 160 118 more more ADV dti-1356 160 119 frequent frequent ADJ dti-1356 160 120 in in ADP dti-1356 160 121 gynecological gynecological ADJ dti-1356 160 122 disorders disorder NOUN dti-1356 160 123 than than ADP dti-1356 160 124 in in ADP dti-1356 160 125 gastrointestinal gastrointestinal ADJ dti-1356 160 126 disorders disorder NOUN dti-1356 160 127 . . PUNCT dti-1356 161 1 nevertheless nevertheless ADV dti-1356 161 2 , , PUNCT dti-1356 161 3 the the DET dti-1356 161 4 presence presence NOUN dti-1356 161 5 of of ADP dti-1356 161 6 lh lh PROPN dti-1356 161 7 receptors receptor NOUN dti-1356 161 8 in in ADP dti-1356 161 9 genital genital ADJ dti-1356 161 10 organs organ NOUN dti-1356 161 11 and and CCONJ dti-1356 161 12 the the DET dti-1356 161 13 gastrointestinal gastrointestinal ADJ dti-1356 161 14 tract7,8,34 tract7,8,34 NOUN dti-1356 161 15 could could AUX dti-1356 161 16 be be AUX dti-1356 161 17 a a DET dti-1356 161 18 plausible plausible ADJ dti-1356 161 19 explanation explanation NOUN dti-1356 161 20 for for ADP dti-1356 161 21 the the DET dti-1356 161 22 observed observed ADJ dti-1356 161 23 connection connection NOUN dti-1356 161 24 between between ADP dti-1356 161 25 dysfunction dysfunction NOUN dti-1356 161 26 of of ADP dti-1356 161 27 the the DET dti-1356 161 28 digestive digestive ADJ dti-1356 161 29 tract tract NOUN dti-1356 161 30 and and CCONJ dti-1356 161 31 diseases disease NOUN dti-1356 161 32 of of ADP dti-1356 161 33 the the DET dti-1356 161 34 genital genital ADJ dti-1356 161 35 organs organ NOUN dti-1356 161 36 in in ADP dti-1356 161 37 women.37–39 women.37–39 NUM dti-1356 161 38 http://www.la-press.com http://www.la-press.com X dti-1356 161 39 http://www.la-press.com/drug-target-insights-journal-j23 http://www.la-press.com/drug-target-insights-journal-j23 AUX dti-1356 161 40 roth roth PROPN dti-1356 161 41 et et PROPN dti-1356 161 42 al al PROPN dti-1356 161 43 50 50 NUM dti-1356 161 44 drug drug NOUN dti-1356 161 45 target target NOUN dti-1356 161 46 insights insight NOUN dti-1356 161 47 2014:8 2014:8 NUM dti-1356 161 48 in in ADP dti-1356 161 49 conclusion conclusion NOUN dti-1356 161 50 , , PUNCT dti-1356 161 51 we we PRON dti-1356 161 52 confirm confirm VERB dti-1356 161 53 previous previous ADJ dti-1356 161 54 results result NOUN dti-1356 161 55 that that PRON dti-1356 161 56 igm igm PROPN dti-1356 161 57 antibodies antibodie VERB dti-1356 161 58 against against ADP dti-1356 161 59 gnrh1 gnrh1 NOUN dti-1356 161 60 are be AUX dti-1356 161 61 elevated elevate VERB dti-1356 161 62 in in ADP dti-1356 161 63 serum serum NOUN dti-1356 161 64 in in ADP dti-1356 161 65 patients patient NOUN dti-1356 161 66 with with ADP dti-1356 161 67 ibs ibs PROPN dti-1356 161 68 , , PUNCT dti-1356 161 69 dysmotility dysmotility NOUN dti-1356 161 70 , , PUNCT dti-1356 161 71 and/or and/or CCONJ dti-1356 161 72 diabetes diabete VERB dti-1356 161 73 mellitus mellitus NOUN dti-1356 161 74 compared compare VERB dti-1356 161 75 to to ADP dti-1356 161 76 controls control NOUN dti-1356 161 77 . . PUNCT dti-1356 162 1 furthermore furthermore ADV dti-1356 162 2 , , PUNCT dti-1356 162 3 also also ADV dti-1356 162 4 igm igm PROPN dti-1356 162 5 antibodies antibodie VERB dti-1356 162 6 against against ADP dti-1356 162 7 progonadoliberin-2 progonadoliberin-2 NUM dti-1356 162 8 and and CCONJ dti-1356 162 9 gnrh gnrh NOUN dti-1356 162 10 receptors receptor NOUN dti-1356 162 11 are be AUX dti-1356 162 12 elevated elevate VERB dti-1356 162 13 in in ADP dti-1356 162 14 these these DET dti-1356 162 15 patients patient NOUN dti-1356 162 16 , , PUNCT dti-1356 162 17 whereas whereas SCONJ dti-1356 162 18 igg igg PROPN dti-1356 162 19 antibodies antibodie VERB dti-1356 162 20 against against ADP dti-1356 162 21 these these DET dti-1356 162 22 peptides peptide NOUN dti-1356 162 23 , , PUNCT dti-1356 162 24 or or CCONJ dti-1356 162 25 antibodies antibodie VERB dti-1356 162 26 against against ADP dti-1356 162 27 lh lh PROPN dti-1356 162 28 or or CCONJ dti-1356 162 29 lh lh PROPN dti-1356 162 30 receptor receptor NOUN dti-1356 162 31 , , PUNCT dti-1356 162 32 are be AUX dti-1356 162 33 not not PART dti-1356 162 34 present present ADJ dti-1356 162 35 . . PUNCT dti-1356 163 1 it it PRON dti-1356 163 2 remains remain VERB dti-1356 163 3 to to PART dti-1356 163 4 explain explain VERB dti-1356 163 5 the the DET dti-1356 163 6 mechanisms mechanism NOUN dti-1356 163 7 behind behind ADP dti-1356 163 8 the the DET dti-1356 163 9 antibody antibody NOUN dti-1356 163 10 formation formation NOUN dti-1356 163 11 and and CCONJ dti-1356 163 12 to to PART dti-1356 163 13 examine examine VERB dti-1356 163 14 whether whether SCONJ dti-1356 163 15 the the DET dti-1356 163 16 gastrointestinal gastrointestinal ADJ dti-1356 163 17 complaints complaint NOUN dti-1356 163 18 , , PUNCT dti-1356 163 19 the the DET dti-1356 163 20 autonomic autonomic ADJ dti-1356 163 21 neuropathy neuropathy ADJ dti-1356 163 22 , , PUNCT dti-1356 163 23 or or CCONJ dti-1356 163 24 the the DET dti-1356 163 25 psychological psychological ADJ dti-1356 163 26 factors factor NOUN dti-1356 163 27 are be AUX dti-1356 163 28 associated associate VERB dti-1356 163 29 with with ADP dti-1356 163 30 the the DET dti-1356 163 31 formation formation NOUN dti-1356 163 32 . . PUNCT dti-1356 164 1 abbreviations abbreviation NOUN dti-1356 164 2 cipo cipo PROPN dti-1356 164 3 , , PUNCT dti-1356 164 4 chronic chronic ADJ dti-1356 164 5 intestinal intestinal ADJ dti-1356 164 6 pseudo pseudo NOUN dti-1356 164 7 - - NOUN dti-1356 164 8 obstruction obstruction NOUN dti-1356 164 9 ; ; PUNCT dti-1356 164 10 ed ed NOUN dti-1356 164 11 , , PUNCT dti-1356 164 12 enteric enteric ADJ dti-1356 164 13 dysmotility dysmotility NOUN dti-1356 164 14 ; ; PUNCT dti-1356 164 15 ens en NOUN dti-1356 164 16 , , PUNCT dti-1356 164 17 enteric enteric ADJ dti-1356 164 18 nervous nervous ADJ dti-1356 164 19 system system NOUN dti-1356 164 20 ; ; PUNCT dti-1356 164 21 gnrh gnrh NOUN dti-1356 164 22 , , PUNCT dti-1356 164 23 gonadotropin gonadotropin NOUN dti-1356 164 24 - - PUNCT dti-1356 164 25 releasing release VERB dti-1356 164 26 hormone hormone NOUN dti-1356 164 27 ; ; PUNCT dti-1356 164 28 ibs ibs PROPN dti-1356 164 29 , , PUNCT dti-1356 164 30 irritable irritable ADJ dti-1356 164 31 bowel bowel NOUN dti-1356 164 32 syndrome syndrome NOUN dti-1356 164 33 ; ; PUNCT dti-1356 164 34 ivf ivf NOUN dti-1356 164 35 , , PUNCT dti-1356 164 36 in in ADP dti-1356 164 37 vitro vitro X dti-1356 164 38 fertilization fertilization NOUN dti-1356 164 39 ; ; PUNCT dti-1356 164 40 lh lh PROPN dti-1356 164 41 , , PUNCT dti-1356 164 42 luteinizing luteinize VERB dti-1356 164 43 hormone hormone NOUN dti-1356 164 44 . . PUNCT dti-1356 165 1 author author NOUN dti-1356 165 2 contributions contribution NOUN dti-1356 165 3 conceived conceive VERB dti-1356 165 4 and and CCONJ dti-1356 165 5 designed design VERB dti-1356 165 6 the the DET dti-1356 165 7 experiments experiment NOUN dti-1356 165 8 : : PUNCT dti-1356 165 9 br br PROPN dti-1356 165 10 , , PUNCT dti-1356 165 11 kb kb PROPN dti-1356 165 12 , , PUNCT dti-1356 165 13 and and CCONJ dti-1356 165 14 bo bo PROPN dti-1356 165 15 . . PROPN dti-1356 165 16 analyzed analyze VERB dti-1356 165 17 the the DET dti-1356 165 18 data datum NOUN dti-1356 165 19 : : PUNCT dti-1356 166 1 br br PROPN dti-1356 166 2 and and CCONJ dti-1356 166 3 bo bo PROPN dti-1356 166 4 . . PROPN dti-1356 166 5 wrote write VERB dti-1356 166 6 the the DET dti-1356 166 7 first first ADJ dti-1356 166 8 draft draft NOUN dti-1356 166 9 of of ADP dti-1356 166 10 the the DET dti-1356 166 11 manuscript manuscript NOUN dti-1356 166 12 : : PUNCT dti-1356 166 13 bo bo PROPN dti-1356 166 14 . . PROPN dti-1356 166 15 contributed contribute VERB dti-1356 166 16 to to ADP dti-1356 166 17 the the DET dti-1356 166 18 writing writing NOUN dti-1356 166 19 of of ADP dti-1356 166 20 the the DET dti-1356 166 21 manuscript manuscript NOUN dti-1356 166 22 : : PUNCT dti-1356 166 23 br br PROPN dti-1356 166 24 and and CCONJ dti-1356 166 25 kb kb PROPN dti-1356 166 26 . . PROPN dti-1356 167 1 agree agree VERB dti-1356 167 2 with with ADP dti-1356 167 3 manuscript manuscript NOUN dti-1356 167 4 results result NOUN dti-1356 167 5 and and CCONJ dti-1356 167 6 conclusions conclusion NOUN dti-1356 167 7 : : PUNCT dti-1356 167 8 br br PROPN dti-1356 167 9 , , PUNCT dti-1356 167 10 kb kb PROPN dti-1356 167 11 , , PUNCT dti-1356 167 12 and and CCONJ dti-1356 167 13 bo bo PROPN dti-1356 167 14 . . PUNCT dti-1356 168 1 jointly jointly ADV dti-1356 168 2 developed develop VERB dti-1356 168 3 the the DET dti-1356 168 4 structure structure NOUN dti-1356 168 5 and and CCONJ dti-1356 168 6 arguments argument NOUN dti-1356 168 7 for for ADP dti-1356 168 8 the the DET dti-1356 168 9 paper paper NOUN dti-1356 168 10 : : PUNCT dti-1356 168 11 br br PROPN dti-1356 168 12 , , PUNCT dti-1356 168 13 kb kb PROPN dti-1356 168 14 , , PUNCT dti-1356 168 15 and and CCONJ dti-1356 168 16 bo bo PROPN dti-1356 168 17 . . PROPN dti-1356 168 18 made make VERB dti-1356 168 19 critical critical ADJ dti-1356 168 20 revisions revision NOUN dti-1356 168 21 and and CCONJ dti-1356 168 22 approved approve VERB dti-1356 168 23 final final ADJ dti-1356 168 24 version version NOUN dti-1356 168 25 : : PUNCT dti-1356 168 26 br br PROPN dti-1356 168 27 , , PUNCT dti-1356 168 28 kb kb PROPN dti-1356 168 29 , , PUNCT dti-1356 168 30 and and CCONJ dti-1356 168 31 bo bo INTJ dti-1356 168 32 . . PUNCT dti-1356 169 1 all all DET dti-1356 169 2 authors author NOUN dti-1356 169 3 reviewed review VERB dti-1356 169 4 and and CCONJ dti-1356 169 5 approved approve VERB dti-1356 169 6 of of ADP dti-1356 169 7 the the DET dti-1356 169 8 final final ADJ dti-1356 169 9 manuscript manuscript NOUN dti-1356 169 10 . . PUNCT dti-1356 170 1 references reference NOUN dti-1356 170 2 1 1 NUM dti-1356 170 3 . . PUNCT dti-1356 170 4 longstreth longstreth PROPN dti-1356 170 5 gf gf PROPN dti-1356 170 6 , , PUNCT dti-1356 170 7 thompson thompson PROPN dti-1356 170 8 wg wg PROPN dti-1356 170 9 , , PUNCT dti-1356 170 10 chey chey PROPN dti-1356 170 11 wd wd PROPN dti-1356 170 12 , , PUNCT dti-1356 170 13 houghton houghton PROPN dti-1356 170 14 la la PROPN dti-1356 170 15 , , PUNCT dti-1356 170 16 mearin mearin PROPN dti-1356 170 17 f f PROPN dti-1356 170 18 , , PUNCT dti-1356 170 19 spiller spiller PROPN dti-1356 170 20 rc rc PROPN dti-1356 170 21 . . PROPN dti-1356 170 22 functional functional ADJ dti-1356 170 23 bowel bowel NOUN dti-1356 170 24 disorders disorder NOUN dti-1356 170 25 . . PUNCT dti-1356 171 1 gastroenterology gastroenterology NOUN dti-1356 171 2 . . PUNCT dti-1356 172 1 2006;130:1480–1491 2006;130:1480–1491 NUM dti-1356 172 2 . . X dti-1356 173 1 2 2 NUM dti-1356 173 2 . . X dti-1356 173 3 ohlsson ohlsson PROPN dti-1356 173 4 b b PROPN dti-1356 173 5 , , PUNCT dti-1356 173 6 melander melander ADJ dti-1356 173 7 o o NOUN dti-1356 173 8 , , PUNCT dti-1356 173 9 thorson thorson PROPN dti-1356 173 10 o o NOUN dti-1356 173 11 , , PUNCT dti-1356 173 12 olsson olsson PROPN dti-1356 173 13 r r PROPN dti-1356 173 14 , , PUNCT dti-1356 173 15 ekberg ekberg PROPN dti-1356 173 16 o o NOUN dti-1356 173 17 , , PUNCT dti-1356 173 18 sundkvist sundkvist NOUN dti-1356 173 19 g. g. PROPN dti-1356 173 20 oesophageal oesophageal PROPN dti-1356 173 21 dysmotility dysmotility NOUN dti-1356 173 22 , , PUNCT dti-1356 173 23 delayed delay VERB dti-1356 173 24 gastric gastric ADJ dti-1356 173 25 emptying empty VERB dti-1356 173 26 and and CCONJ dti-1356 173 27 autonomic autonomic ADJ dti-1356 173 28 neuropathy neuropathy ADJ dti-1356 173 29 correlate correlate VERB dti-1356 173 30 to to ADP dti-1356 173 31 disturbed disturbed ADJ dti-1356 173 32 glucose glucose NOUN dti-1356 173 33 homeostasis homeostasis NOUN dti-1356 173 34 . . PUNCT dti-1356 174 1 diabetologia diabetologia NOUN dti-1356 174 2 . . PUNCT dti-1356 175 1 2006;49:2010–2014 2006;49:2010–2014 NOUN dti-1356 175 2 . . PUNCT dti-1356 176 1 3 3 X dti-1356 176 2 . . X dti-1356 176 3 ohlsson ohlsson PROPN dti-1356 176 4 b b PROPN dti-1356 176 5 , , PUNCT dti-1356 176 6 scheja scheja NOUN dti-1356 176 7 a a NOUN dti-1356 176 8 , , PUNCT dti-1356 176 9 janciauskiene janciauskiene NOUN dti-1356 176 10 s s PROPN dti-1356 176 11 , , PUNCT dti-1356 176 12 mandl mandl PROPN dti-1356 176 13 t. t. PROPN dti-1356 176 14 gnrh gnrh NOUN dti-1356 176 15 - - PUNCT dti-1356 176 16 antibodies antibody NOUN dti-1356 176 17 and and CCONJ dti-1356 176 18 gastrointestinal gastrointestinal ADJ dti-1356 176 19 complaints complaint NOUN dti-1356 176 20 in in ADP dti-1356 176 21 patients patient NOUN dti-1356 176 22 with with ADP dti-1356 176 23 sjögren sjögren PROPN dti-1356 176 24 ’s ’s PART dti-1356 176 25 syndrome syndrome NOUN dti-1356 176 26 and and CCONJ dti-1356 176 27 progressive progressive ADJ dti-1356 176 28 systemic systemic ADJ dti-1356 176 29 sclerosis sclerosis NOUN dti-1356 176 30 . . PUNCT dti-1356 177 1 scand scand PROPN dti-1356 177 2 j j PROPN dti-1356 177 3 rheumatol rheumatol NOUN dti-1356 177 4 . . PUNCT dti-1356 178 1 2009;23:1–2 2009;23:1–2 NUM dti-1356 178 2 . . PUNCT dti-1356 179 1 4 4 X dti-1356 179 2 . . X dti-1356 179 3 canavan canavan NOUN dti-1356 179 4 c c PROPN dti-1356 179 5 , , PUNCT dti-1356 179 6 west west PROPN dti-1356 179 7 j j PROPN dti-1356 179 8 , , PUNCT dti-1356 179 9 card card NOUN dti-1356 179 10 t. t. PROPN dti-1356 179 11 the the DET dti-1356 179 12 epidemiology epidemiology NOUN dti-1356 179 13 of of ADP dti-1356 179 14 irritable irritable ADJ dti-1356 179 15 bowel bowel NOUN dti-1356 179 16 syndrome syndrome NOUN dti-1356 179 17 . . PUNCT dti-1356 180 1 clin clin PROPN dti-1356 180 2 epidemiol epidemiol PROPN dti-1356 180 3 . . PUNCT dti-1356 181 1 2014;6:71–80 2014;6:71–80 NUM dti-1356 181 2 . . NOUN dti-1356 182 1 5 5 NUM dti-1356 182 2 . . PUNCT dti-1356 182 3 ohlsson ohlsson PROPN dti-1356 182 4 b b PROPN dti-1356 182 5 , , PUNCT dti-1356 182 6 veréss veréss PROPN dti-1356 182 7 b b NOUN dti-1356 182 8 , , PUNCT dti-1356 182 9 janciauskiene janciauskiene NOUN dti-1356 182 10 s s PROPN dti-1356 182 11 , , PUNCT dti-1356 182 12 montgomery montgomery PROPN dti-1356 182 13 a a PRON dti-1356 182 14 , , PUNCT dti-1356 182 15 haglund haglund NOUN dti-1356 182 16 m m PROPN dti-1356 182 17 , , PUNCT dti-1356 182 18 wallmark wallmark ADJ dti-1356 182 19 a. a. NOUN dti-1356 182 20 chronic chronic ADJ dti-1356 182 21 intestinal intestinal ADJ dti-1356 182 22 pseudo pseudo NOUN dti-1356 182 23 - - NOUN dti-1356 182 24 obstruction obstruction NOUN dti-1356 182 25 due due ADJ dti-1356 182 26 to to ADP dti-1356 182 27 buserelin buserelin NOUN dti-1356 182 28 - - PUNCT dti-1356 182 29 induced induce VERB dti-1356 182 30 formation formation NOUN dti-1356 182 31 of of ADP dti-1356 182 32 anti anti ADJ dti-1356 182 33 - - ADJ dti-1356 182 34 gnrh gnrh NOUN dti-1356 182 35 antibodies antibodie VERB dti-1356 182 36 . . PUNCT dti-1356 183 1 gastroenterology gastroenterology NOUN dti-1356 183 2 . . PUNCT dti-1356 184 1 2007;132:45–51 2007;132:45–51 NUM dti-1356 184 2 . . NOUN dti-1356 185 1 6 6 NUM dti-1356 185 2 . . X dti-1356 185 3 hammar hammar PROPN dti-1356 185 4 o o PROPN dti-1356 185 5 , , PUNCT dti-1356 185 6 ohlsson ohlsson PROPN dti-1356 185 7 b b PROPN dti-1356 185 8 , , PUNCT dti-1356 185 9 veress veress NOUN dti-1356 185 10 b b PROPN dti-1356 185 11 , , PUNCT dti-1356 185 12 nordin nordin PROPN dti-1356 185 13 fredrikson fredrikson PROPN dti-1356 185 14 g g PROPN dti-1356 185 15 , , PUNCT dti-1356 185 16 alm alm NOUN dti-1356 185 17 r r PROPN dti-1356 185 18 , , PUNCT dti-1356 185 19 montgomery montgomery PROPN dti-1356 185 20 a. a. NOUN dti-1356 185 21 depletion depletion NOUN dti-1356 185 22 of of ADP dti-1356 185 23 enteric enteric ADJ dti-1356 185 24 gonadotropin gonadotropin NOUN dti-1356 185 25 - - PUNCT dti-1356 185 26 releasing release VERB dti-1356 185 27 hormone hormone NOUN dti-1356 185 28 is be AUX dti-1356 185 29 found find VERB dti-1356 185 30 in in ADP dti-1356 185 31 a a DET dti-1356 185 32 few few ADJ dti-1356 185 33 patients patient NOUN dti-1356 185 34 suffering suffer VERB dti-1356 185 35 from from ADP dti-1356 185 36 severe severe ADJ dti-1356 185 37 gastrointestinal gastrointestinal ADJ dti-1356 185 38 dysmotility dysmotility NOUN dti-1356 185 39 . . PUNCT dti-1356 186 1 scand scand PROPN dti-1356 186 2 j j PROPN dti-1356 186 3 gastroenterol gastroenterol PROPN dti-1356 186 4 . . PUNCT dti-1356 187 1 2012 2012 NUM dti-1356 187 2 ; ; PUNCT dti-1356 188 1 47:1165–1173 47:1165–1173 NUM dti-1356 188 2 . . PROPN dti-1356 189 1 7 7 X dti-1356 189 2 . . X dti-1356 189 3 hammar hammar PROPN dti-1356 189 4 o o PROPN dti-1356 189 5 , , PUNCT dti-1356 189 6 veress veress NOUN dti-1356 189 7 b b PROPN dti-1356 189 8 , , PUNCT dti-1356 189 9 montgomery montgomery PROPN dti-1356 189 10 a a X dti-1356 189 11 , , PUNCT dti-1356 189 12 ohlsson ohlsson PROPN dti-1356 189 13 b. b. PROPN dti-1356 189 14 expression expression NOUN dti-1356 189 15 of of ADP dti-1356 189 16 luteinizing luteinize VERB dti-1356 189 17 hormone hormone NOUN dti-1356 189 18 receptor receptor NOUN dti-1356 189 19 in in ADP dti-1356 189 20 the the DET dti-1356 189 21 gastrointestinal gastrointestinal ADJ dti-1356 189 22 tract tract NOUN dti-1356 189 23 in in ADP dti-1356 189 24 patients patient NOUN dti-1356 189 25 with with ADP dti-1356 189 26 and and CCONJ dti-1356 189 27 without without ADP dti-1356 189 28 dysmotility dysmotility NOUN dti-1356 189 29 . . PUNCT dti-1356 190 1 dti dti PROPN dti-1356 190 2 . . PROPN dti-1356 190 3 2012;6:13–18 2012;6:13–18 NUM dti-1356 190 4 . . NOUN dti-1356 190 5 8 8 NUM dti-1356 190 6 . . PUNCT dti-1356 190 7 sand sand NOUN dti-1356 190 8 e e NOUN dti-1356 190 9 , , PUNCT dti-1356 190 10 bergvall bergvall PROPN dti-1356 190 11 m m PROPN dti-1356 190 12 , , PUNCT dti-1356 190 13 ekblad ekblad VERB dti-1356 190 14 e e NOUN dti-1356 190 15 , , PUNCT dti-1356 190 16 d’amato d’amato VERB dti-1356 190 17 m m PRON dti-1356 190 18 , , PUNCT dti-1356 190 19 ohlsson ohlsson PROPN dti-1356 190 20 b. b. PROPN dti-1356 190 21 expression expression NOUN dti-1356 190 22 and and CCONJ dti-1356 190 23 distribution distribution NOUN dti-1356 190 24 of of ADP dti-1356 190 25 gnrh gnrh NOUN dti-1356 190 26 , , PUNCT dti-1356 190 27 lh lh PROPN dti-1356 190 28 , , PUNCT dti-1356 190 29 and and CCONJ dti-1356 190 30 fsh fsh NOUN dti-1356 190 31 and and CCONJ dti-1356 190 32 their their PRON dti-1356 190 33 receptors receptor NOUN dti-1356 190 34 in in ADP dti-1356 190 35 gastrointestinal gastrointestinal ADJ dti-1356 190 36 tract tract NOUN dti-1356 190 37 of of ADP dti-1356 190 38 man man NOUN dti-1356 190 39 and and CCONJ dti-1356 190 40 rat rat NOUN dti-1356 190 41 . . PROPN dti-1356 190 42 regul regul PROPN dti-1356 190 43 pept pept PROPN dti-1356 190 44 . . PUNCT dti-1356 191 1 2013;10:24–28 2013;10:24–28 NUM dti-1356 191 2 . . PUNCT dti-1356 192 1 9 9 X dti-1356 192 2 . . X dti-1356 192 3 khanna khanna PROPN dti-1356 192 4 r r PROPN dti-1356 192 5 , , PUNCT dti-1356 192 6 browne browne PROPN dti-1356 192 7 rm rm PROPN dti-1356 192 8 , , PUNCT dti-1356 192 9 heiner heiner PROPN dti-1356 192 10 ad ad NOUN dti-1356 192 11 , , PUNCT dti-1356 192 12 clench clench PROPN dti-1356 192 13 mh mh PROPN dti-1356 192 14 , , PUNCT dti-1356 192 15 mathias mathias PROPN dti-1356 192 16 jr jr PROPN dti-1356 192 17 . . PROPN dti-1356 192 18 leuprolide leuprolide PROPN dti-1356 192 19 acetate acetate NOUN dti-1356 192 20 affects affect VERB dti-1356 192 21 intestinal intestinal ADJ dti-1356 192 22 motility motility NOUN dti-1356 192 23 in in ADP dti-1356 192 24 female female ADJ dti-1356 192 25 rats rat NOUN dti-1356 192 26 before before ADP dti-1356 192 27 and and CCONJ dti-1356 192 28 after after ADP dti-1356 192 29 ovariectomy ovariectomy NOUN dti-1356 192 30 . . PUNCT dti-1356 193 1 am be AUX dti-1356 193 2 j j PROPN dti-1356 193 3 physiol physiol PROPN dti-1356 193 4 . . PUNCT dti-1356 194 1 1992;262 1992;262 NUM dti-1356 194 2 : : PUNCT dti-1356 194 3 g185 g185 NUM dti-1356 194 4 – – PUNCT dti-1356 194 5 g190 g190 NUM dti-1356 194 6 . . PUNCT dti-1356 195 1 10 10 NUM dti-1356 195 2 . . PUNCT dti-1356 195 3 mathias mathias PROPN dti-1356 195 4 jr jr PROPN dti-1356 195 5 , , PUNCT dti-1356 195 6 baskin baskin PROPN dti-1356 195 7 gs gs PROPN dti-1356 195 8 , , PUNCT dti-1356 195 9 reeves reeves PROPN dti-1356 195 10 - - PUNCT dti-1356 195 11 darby darby PROPN dti-1356 195 12 vg vg PROPN dti-1356 195 13 , , PUNCT dti-1356 195 14 clench clench NOUN dti-1356 195 15 mh mh PROPN dti-1356 195 16 , , PUNCT dti-1356 195 17 smith smith PROPN dti-1356 195 18 ll ll PROPN dti-1356 195 19 , , PUNCT dti-1356 195 20 calhoon calhoon VERB dti-1356 195 21 jh jh PROPN dti-1356 195 22 . . PUNCT dti-1356 196 1 chronic chronic ADJ dti-1356 196 2 intestinal intestinal ADJ dti-1356 196 3 pseudoobstruction pseudoobstruction NOUN dti-1356 196 4 in in ADP dti-1356 196 5 a a DET dti-1356 196 6 patient patient NOUN dti-1356 196 7 with with ADP dti-1356 196 8 heart heart NOUN dti-1356 196 9 - - PUNCT dti-1356 196 10 lung lung NOUN dti-1356 196 11 transplant transplant NOUN dti-1356 196 12 . . PUNCT dti-1356 197 1 therapeutic therapeutic ADJ dti-1356 197 2 effect effect NOUN dti-1356 197 3 of of ADP dti-1356 197 4 leuprolide leuprolide NOUN dti-1356 197 5 acetate acetate NOUN dti-1356 197 6 . . PUNCT dti-1356 198 1 dig dig VERB dti-1356 198 2 dis dis PROPN dti-1356 198 3 sci sci PROPN dti-1356 198 4 . . PUNCT dti-1356 199 1 1992;37:1761–1768 1992;37:1761–1768 PROPN dti-1356 199 2 . . PUNCT dti-1356 200 1 11 11 NUM dti-1356 200 2 . . PUNCT dti-1356 201 1 ducker ducker NOUN dti-1356 201 2 te te PROPN dti-1356 201 3 , , PUNCT dti-1356 201 4 boss boss PROPN dti-1356 201 5 jw jw PROPN dti-1356 201 6 , , PUNCT dti-1356 201 7 altug altug PROPN dti-1356 201 8 sa sa PROPN dti-1356 201 9 , , PUNCT dti-1356 201 10 et et PROPN dti-1356 201 11 al al PROPN dti-1356 201 12 . . PUNCT dti-1356 202 1 luteinizing luteinize VERB dti-1356 202 2 hormone hormone NOUN dti-1356 202 3 and and CCONJ dti-1356 202 4 human human ADJ dti-1356 202 5 chorionic chorionic ADJ dti-1356 202 6 gonadotropin gonadotropin NOUN dti-1356 202 7 fragment fragment VERB dti-1356 202 8 the the DET dti-1356 202 9 migrating migrating NOUN dti-1356 202 10 myoelectric myoelectric ADJ dti-1356 202 11 complex complex NOUN dti-1356 202 12 in in ADP dti-1356 202 13 rat rat NOUN dti-1356 202 14 small small ADJ dti-1356 202 15 intestine intestine NOUN dti-1356 202 16 . . PUNCT dti-1356 203 1 neurogastroenterol neurogastroenterol PROPN dti-1356 203 2 motil motil PROPN dti-1356 203 3 . . PUNCT dti-1356 204 1 1996;8:95–100 1996;8:95–100 NUM dti-1356 204 2 . . PUNCT dti-1356 204 3 12 12 NUM dti-1356 204 4 . . PUNCT dti-1356 205 1 ohlsson ohlsson PROPN dti-1356 205 2 b b PROPN dti-1356 205 3 , , PUNCT dti-1356 205 4 sjöberg sjöberg PROPN dti-1356 205 5 k k PROPN dti-1356 205 6 , , PUNCT dti-1356 205 7 alm alm PROPN dti-1356 205 8 r r PROPN dti-1356 205 9 , , PUNCT dti-1356 205 10 nordin nordin PROPN dti-1356 205 11 fredrikson fredrikson PROPN dti-1356 205 12 g. g. PROPN dti-1356 205 13 patients patient NOUN dti-1356 205 14 with with ADP dti-1356 205 15 irritable irritable ADJ dti-1356 205 16 bowel bowel NOUN dti-1356 205 17 syndrome syndrome NOUN dti-1356 205 18 and and CCONJ dti-1356 205 19 dysmotility dysmotility NOUN dti-1356 205 20 express express VERB dti-1356 205 21 antibodies antibody NOUN dti-1356 205 22 against against ADP dti-1356 205 23 gonadotropinreleasing gonadotropinrelease VERB dti-1356 205 24 hormone hormone NOUN dti-1356 205 25 in in ADP dti-1356 205 26 serum serum NOUN dti-1356 205 27 . . PUNCT dti-1356 206 1 neurogastroenterol neurogastroenterol PROPN dti-1356 206 2 motil motil PROPN dti-1356 206 3 . . PUNCT dti-1356 207 1 2011;23:1000–1006 2011;23:1000–1006 NUM dti-1356 207 2 . . PUNCT dti-1356 208 1 13 13 NUM dti-1356 208 2 . . PUNCT dti-1356 208 3 berntorp berntorp PROPN dti-1356 208 4 k k PROPN dti-1356 208 5 , , PUNCT dti-1356 208 6 frid frid PROPN dti-1356 208 7 a a PRON dti-1356 208 8 , , PUNCT dti-1356 208 9 alm alm NOUN dti-1356 208 10 r r NOUN dti-1356 208 11 , , PUNCT dti-1356 208 12 fredrikson fredrikson PROPN dti-1356 208 13 gn gn PROPN dti-1356 208 14 , , PUNCT dti-1356 208 15 sjöberg sjöberg PROPN dti-1356 208 16 k k PROPN dti-1356 208 17 , , PUNCT dti-1356 208 18 ohlsson ohlsson PROPN dti-1356 208 19 b. b. PROPN dti-1356 208 20 antibodies antibodie VERB dti-1356 208 21 against against ADP dti-1356 208 22 gonadotropin gonadotropin NOUN dti-1356 208 23 - - PUNCT dti-1356 208 24 releasing release VERB dti-1356 208 25 hormone hormone NOUN dti-1356 208 26 ( ( PUNCT dti-1356 208 27 gnrh gnrh NOUN dti-1356 208 28 ) ) PUNCT dti-1356 208 29 in in ADP dti-1356 208 30 patients patient NOUN dti-1356 208 31 with with ADP dti-1356 208 32 diabetes diabetes NOUN dti-1356 208 33 mellitus mellitus NOUN dti-1356 208 34 is be AUX dti-1356 208 35 associated associate VERB dti-1356 208 36 with with ADP dti-1356 208 37 lower low ADJ dti-1356 208 38 body body NOUN dti-1356 208 39 weight weight NOUN dti-1356 208 40 and and CCONJ dti-1356 208 41 autonomic autonomic ADJ dti-1356 208 42 neuropathy neuropathy ADJ dti-1356 208 43 . . PUNCT dti-1356 209 1 bmc bmc ADJ dti-1356 209 2 res re NOUN dti-1356 209 3 notes note NOUN dti-1356 209 4 . . PUNCT dti-1356 210 1 2013;6:329 2013;6:329 X dti-1356 210 2 . . PUNCT dti-1356 211 1 14 14 NUM dti-1356 211 2 . . PUNCT dti-1356 212 1 mandl mandl PROPN dti-1356 212 2 t t PROPN dti-1356 212 3 , , PUNCT dti-1356 212 4 roth roth PROPN dti-1356 212 5 b b PROPN dti-1356 212 6 , , PUNCT dti-1356 212 7 ohlsson ohlsson PROPN dti-1356 212 8 b. b. PROPN dti-1356 212 9 antibodies antibodie VERB dti-1356 212 10 against against ADP dti-1356 212 11 gnrh gnrh NOUN dti-1356 212 12 and and CCONJ dti-1356 212 13 its its PRON dti-1356 212 14 receptor receptor NOUN dti-1356 212 15 in in ADP dti-1356 212 16 patients patient NOUN dti-1356 212 17 with with ADP dti-1356 212 18 primary primary ADJ dti-1356 212 19 sjögren sjögren PROPN dti-1356 212 20 ’s ’s PART dti-1356 212 21 syndrome syndrome NOUN dti-1356 212 22 . . PUNCT dti-1356 213 1 scand scand PROPN dti-1356 213 2 j j PROPN dti-1356 213 3 rheumatol rheumatol NOUN dti-1356 213 4 . . PUNCT dti-1356 214 1 2014;43:338–348 2014;43:338–348 NUM dti-1356 214 2 . . PUNCT dti-1356 215 1 15 15 NUM dti-1356 215 2 . . PUNCT dti-1356 216 1 roth roth PROPN dti-1356 216 2 b b PROPN dti-1356 216 3 , , PUNCT dti-1356 216 4 ohlsson ohlsson PROPN dti-1356 216 5 b. b. PROPN dti-1356 216 6 gastrointestinal gastrointestinal ADJ dti-1356 216 7 symptoms symptom NOUN dti-1356 216 8 and and CCONJ dti-1356 216 9 psychological psychological ADJ dti-1356 216 10 well well ADV dti-1356 216 11 - - PUNCT dti-1356 216 12 being being NOUN dti-1356 216 13 in in ADP dti-1356 216 14 patients patient NOUN dti-1356 216 15 with with ADP dti-1356 216 16 microscopic microscopic ADJ dti-1356 216 17 colitis colitis NOUN dti-1356 216 18 . . PUNCT dti-1356 217 1 scand scand PROPN dti-1356 217 2 j j PROPN dti-1356 217 3 gastroenterol gastroenterol PROPN dti-1356 217 4 . . PUNCT dti-1356 218 1 2013;48:27–34 2013;48:27–34 NUM dti-1356 218 2 . . PUNCT dti-1356 219 1 16 16 NUM dti-1356 219 2 . . PUNCT dti-1356 220 1 hammar hammar PROPN dti-1356 220 2 o o PROPN dti-1356 220 3 , , PUNCT dti-1356 220 4 roth roth PROPN dti-1356 220 5 b b PROPN dti-1356 220 6 , , PUNCT dti-1356 220 7 bengtsson bengtsson PROPN dti-1356 220 8 m m PROPN dti-1356 220 9 , , PUNCT dti-1356 220 10 mandl mandl PROPN dti-1356 220 11 t t PROPN dti-1356 220 12 , , PUNCT dti-1356 220 13 ohlsson ohlsson PROPN dti-1356 220 14 b. b. PROPN dti-1356 220 15 autoantibodies autoantibody NOUN dti-1356 220 16 and and CCONJ dti-1356 220 17 gastrointestinal gastrointestinal ADJ dti-1356 220 18 symptoms symptom NOUN dti-1356 220 19 in in ADP dti-1356 220 20 infertile infertile ADJ dti-1356 220 21 women woman NOUN dti-1356 220 22 in in ADP dti-1356 220 23 relation relation NOUN dti-1356 220 24 to to PART dti-1356 220 25 in in ADP dti-1356 220 26 vitro vitro X dti-1356 220 27 fertilization fertilization NOUN dti-1356 220 28 . . PUNCT dti-1356 221 1 bmc bmc ADJ dti-1356 221 2 pregnancy pregnancy NOUN dti-1356 221 3 childbirth childbirth NOUN dti-1356 221 4 . . PUNCT dti-1356 222 1 2013;13:201 2013;13:201 X dti-1356 222 2 . . PUNCT dti-1356 223 1 17 17 NUM dti-1356 223 2 . . PUNCT dti-1356 224 1 pawson pawson PROPN dti-1356 224 2 aj aj PROPN dti-1356 224 3 , , PUNCT dti-1356 224 4 morgan morgan PROPN dti-1356 224 5 k k PROPN dti-1356 224 6 , , PUNCT dti-1356 224 7 maudsley maudsley PROPN dti-1356 224 8 sr sr PROPN dti-1356 224 9 , , PUNCT dti-1356 224 10 millar millar PROPN dti-1356 224 11 rp rp PROPN dti-1356 224 12 . . PROPN dti-1356 224 13 type type PROPN dti-1356 224 14 ii ii PROPN dti-1356 224 15 gonadotrophinreleasing gonadotrophinrelease VERB dti-1356 224 16 hormone hormone NOUN dti-1356 224 17 ( ( PUNCT dti-1356 224 18 gnrh gnrh NOUN dti-1356 224 19 - - PUNCT dti-1356 224 20 ii ii NOUN dti-1356 224 21 ) ) PUNCT dti-1356 224 22 in in ADP dti-1356 224 23 reproductive reproductive ADJ dti-1356 224 24 biology biology NOUN dti-1356 224 25 . . PUNCT dti-1356 225 1 reproduction reproduction NOUN dti-1356 225 2 . . PUNCT dti-1356 226 1 2003;126 2003;126 NOUN dti-1356 226 2 : : PUNCT dti-1356 226 3 271–278 271–278 NUM dti-1356 226 4 . . NOUN dti-1356 226 5 18 18 NUM dti-1356 226 6 . . PUNCT dti-1356 226 7 collins collins PROPN dti-1356 226 8 pj pj PROPN dti-1356 226 9 , , PUNCT dti-1356 226 10 horowitz horowitz PROPN dti-1356 226 11 m m PROPN dti-1356 226 12 , , PUNCT dti-1356 226 13 cook cook VERB dti-1356 226 14 dj dj NOUN dti-1356 226 15 , , PUNCT dti-1356 226 16 harding harding PROPN dti-1356 226 17 pe pe PROPN dti-1356 226 18 , , PUNCT dti-1356 226 19 shearman shearman NOUN dti-1356 226 20 dj dj NOUN dti-1356 226 21 . . PUNCT dti-1356 227 1 gastric gastric ADJ dti-1356 227 2 emptying empty VERB dti-1356 227 3 in in ADP dti-1356 227 4 normal normal ADJ dti-1356 227 5 subjects subject NOUN dti-1356 227 6 : : PUNCT dti-1356 227 7 a a DET dti-1356 227 8 reproducible reproducible ADJ dti-1356 227 9 technique technique NOUN dti-1356 227 10 using use VERB dti-1356 227 11 a a DET dti-1356 227 12 single single ADJ dti-1356 227 13 scintillation scintillation NOUN dti-1356 227 14 camera camera NOUN dti-1356 227 15 and and CCONJ dti-1356 227 16 computer computer NOUN dti-1356 227 17 system system NOUN dti-1356 227 18 . . PUNCT dti-1356 228 1 gut gut VERB dti-1356 228 2 . . PUNCT dti-1356 229 1 1983;24:1117–1125 1983;24:1117–1125 NUM dti-1356 229 2 . . PUNCT dti-1356 230 1 19 19 NUM dti-1356 230 2 . . X dti-1356 230 3 hanson hanson PROPN dti-1356 230 4 m m PROPN dti-1356 230 5 , , PUNCT dti-1356 230 6 lilja lilja PROPN dti-1356 230 7 b. b. PROPN dti-1356 230 8 gastric gastric PROPN dti-1356 230 9 emptying empty VERB dti-1356 230 10 in in ADP dti-1356 230 11 smokers smoker NOUN dti-1356 230 12 . . PUNCT dti-1356 231 1 scand scand PROPN dti-1356 231 2 j j PROPN dti-1356 231 3 gastroenterol gastroenterol PROPN dti-1356 231 4 . . PUNCT dti-1356 232 1 1987;22 1987;22 NUM dti-1356 232 2 : : PUNCT dti-1356 232 3 1102–1104 1102–1104 NUM dti-1356 232 4 . . PUNCT dti-1356 233 1 20 20 NUM dti-1356 233 2 . . PUNCT dti-1356 234 1 castell castell PROPN dti-1356 234 2 ja ja PROPN dti-1356 234 3 , , PUNCT dti-1356 234 4 dalton dalton PROPN dti-1356 234 5 cb cb PROPN dti-1356 234 6 , , PUNCT dti-1356 234 7 castell castell PROPN dti-1356 234 8 do do VERB dti-1356 234 9 . . PUNCT dti-1356 235 1 on on ADP dti-1356 235 2 - - PUNCT dti-1356 235 3 line line NOUN dti-1356 235 4 computer computer NOUN dti-1356 235 5 analysis analysis NOUN dti-1356 235 6 of of ADP dti-1356 235 7 human human ADJ dti-1356 235 8 lower low ADJ dti-1356 235 9 esophageal esophageal ADJ dti-1356 235 10 sphincter sphincter ADJ dti-1356 235 11 relaxation relaxation NOUN dti-1356 235 12 . . PUNCT dti-1356 236 1 am be AUX dti-1356 236 2 j j PROPN dti-1356 236 3 physiol physiol PROPN dti-1356 236 4 . . PUNCT dti-1356 237 1 1988;255 1988;255 NUM dti-1356 237 2 : : PUNCT dti-1356 237 3 g794 g794 NUM dti-1356 237 4 – – PUNCT dti-1356 237 5 g799 g799 PROPN dti-1356 237 6 . . PROPN dti-1356 238 1 21 21 NUM dti-1356 238 2 . . PUNCT dti-1356 239 1 abrahamsson abrahamsson PROPN dti-1356 239 2 h h PROPN dti-1356 239 3 , , PUNCT dti-1356 239 4 antov antov PROPN dti-1356 239 5 s s PROPN dti-1356 239 6 , , PUNCT dti-1356 239 7 bosaeus bosaeus PROPN dti-1356 239 8 i. i. PROPN dti-1356 239 9 gastrointestinal gastrointestinal PROPN dti-1356 239 10 and and CCONJ dti-1356 239 11 colonic colonic ADJ dti-1356 239 12 segmental segmental ADJ dti-1356 239 13 transit transit NOUN dti-1356 239 14 time time NOUN dti-1356 239 15 evaluated evaluate VERB dti-1356 239 16 by by ADP dti-1356 239 17 a a DET dti-1356 239 18 single single ADJ dti-1356 239 19 abdominal abdominal ADJ dti-1356 239 20 x x NOUN dti-1356 239 21 - - NOUN dti-1356 239 22 ray ray NOUN dti-1356 239 23 in in ADP dti-1356 239 24 healthy healthy ADJ dti-1356 239 25 subjects subject NOUN dti-1356 239 26 and and CCONJ dti-1356 239 27 constipated constipate VERB dti-1356 239 28 patients patient NOUN dti-1356 239 29 . . PUNCT dti-1356 240 1 scand scand PROPN dti-1356 240 2 j j PROPN dti-1356 240 3 gastroenterol gastroenterol PROPN dti-1356 240 4 . . PUNCT dti-1356 241 1 1988;23:72–80 1988;23:72–80 PROPN dti-1356 241 2 . . PUNCT dti-1356 242 1 22 22 NUM dti-1356 242 2 . . PUNCT dti-1356 242 3 spechler spechler PROPN dti-1356 242 4 sj sj PROPN dti-1356 242 5 , , PUNCT dti-1356 242 6 castell castell PROPN dti-1356 242 7 do do VERB dti-1356 242 8 . . PUNCT dti-1356 243 1 classification classification NOUN dti-1356 243 2 of of ADP dti-1356 243 3 oesophageal oesophageal ADJ dti-1356 243 4 motility motility NOUN dti-1356 243 5 abnormalities abnormality NOUN dti-1356 243 6 . . PUNCT dti-1356 244 1 gut gut VERB dti-1356 244 2 . . PUNCT dti-1356 245 1 2001;49:145–151 2001;49:145–151 NOUN dti-1356 245 2 . . PUNCT dti-1356 246 1 23 23 NUM dti-1356 246 2 . . X dti-1356 246 3 de de PROPN dti-1356 246 4 giorgio giorgio PROPN dti-1356 246 5 r r PROPN dti-1356 246 6 , , PUNCT dti-1356 246 7 sarnelli sarnelli NOUN dti-1356 246 8 g g PROPN dti-1356 246 9 , , PUNCT dti-1356 246 10 corinaldesi corinaldesi NOUN dti-1356 246 11 r r NOUN dti-1356 246 12 , , PUNCT dti-1356 246 13 stanghellini stanghellini PROPN dti-1356 246 14 v. v. ADP dti-1356 246 15 advances advance NOUN dti-1356 246 16 in in ADP dti-1356 246 17 our our PRON dti-1356 246 18 understanding understanding NOUN dti-1356 246 19 of of ADP dti-1356 246 20 the the DET dti-1356 246 21 pathology pathology NOUN dti-1356 246 22 of of ADP dti-1356 246 23 chronic chronic ADJ dti-1356 246 24 intestinal intestinal ADJ dti-1356 246 25 pseudo pseudo NOUN dti-1356 246 26 - - NOUN dti-1356 246 27 obstruction obstruction NOUN dti-1356 246 28 . . PUNCT dti-1356 247 1 gut gut INTJ dti-1356 247 2 . . PUNCT dti-1356 248 1 2004;53 2004;53 NUM dti-1356 248 2 : : PUNCT dti-1356 248 3 1549–1552 1549–1552 NUM dti-1356 248 4 . . PUNCT dti-1356 249 1 24 24 NUM dti-1356 249 2 . . PUNCT dti-1356 250 1 wingate wingate PROPN dti-1356 250 2 d d PROPN dti-1356 250 3 , , PUNCT dti-1356 250 4 hongo hongo PROPN dti-1356 250 5 m m PROPN dti-1356 250 6 , , PUNCT dti-1356 250 7 kellow kellow PROPN dti-1356 250 8 j j PROPN dti-1356 250 9 , , PUNCT dti-1356 250 10 lindberg lindberg PROPN dti-1356 250 11 g g PROPN dti-1356 250 12 , , PUNCT dti-1356 250 13 smout smout ADJ dti-1356 250 14 a. a. NOUN dti-1356 250 15 disorders disorder NOUN dti-1356 250 16 of of ADP dti-1356 250 17 gastrointestinal gastrointestinal ADJ dti-1356 250 18 motility motility NOUN dti-1356 250 19 : : PUNCT dti-1356 250 20 towards towards ADP dti-1356 250 21 a a DET dti-1356 250 22 new new ADJ dti-1356 250 23 classification classification NOUN dti-1356 250 24 . . PUNCT dti-1356 251 1 j j PROPN dti-1356 251 2 gastroenterol gastroenterol NOUN dti-1356 251 3 hepatol hepatol ADJ dti-1356 251 4 . . PUNCT dti-1356 252 1 2002 2002 NUM dti-1356 252 2 ; ; PUNCT dti-1356 252 3 17(suppl):s1 17(suppl):s1 NUM dti-1356 252 4 – – PUNCT dti-1356 252 5 s14 s14 NOUN dti-1356 252 6 . . PUNCT dti-1356 253 1 25 25 NUM dti-1356 253 2 . . PUNCT dti-1356 254 1 faraj faraj PROPN dti-1356 254 2 j j PROPN dti-1356 254 3 , , PUNCT dti-1356 254 4 melander melander ADJ dti-1356 254 5 o o NOUN dti-1356 254 6 , , PUNCT dti-1356 254 7 sundkvist sundkvist NOUN dti-1356 254 8 g g PROPN dti-1356 254 9 , , PUNCT dti-1356 254 10 et et PROPN dti-1356 254 11 al al PROPN dti-1356 254 12 . . PROPN dti-1356 254 13 oesophageal oesophageal ADJ dti-1356 254 14 dysmotility dysmotility NOUN dti-1356 254 15 , , PUNCT dti-1356 254 16 delayed delay VERB dti-1356 254 17 gastric gastric ADJ dti-1356 254 18 emptying empty VERB dti-1356 254 19 and and CCONJ dti-1356 254 20 gastrointestinal gastrointestinal ADJ dti-1356 254 21 symptoms symptom NOUN dti-1356 254 22 in in ADP dti-1356 254 23 patients patient NOUN dti-1356 254 24 with with ADP dti-1356 254 25 diabetes diabetes NOUN dti-1356 254 26 mellitus mellitus NOUN dti-1356 254 27 . . PUNCT dti-1356 255 1 diabet diabet PROPN dti-1356 255 2 med med PROPN dti-1356 255 3 . . PUNCT dti-1356 256 1 2007;24:1235–1239 2007;24:1235–1239 NUM dti-1356 256 2 . . PUNCT dti-1356 257 1 26 26 NUM dti-1356 257 2 . . PUNCT dti-1356 258 1 gustafsson gustafsson PROPN dti-1356 258 2 rj rj PROPN dti-1356 258 3 , , PUNCT dti-1356 258 4 littorin littorin PROPN dti-1356 258 5 b b PROPN dti-1356 258 6 , , PUNCT dti-1356 258 7 berntorp berntorp PROPN dti-1356 258 8 k k PROPN dti-1356 258 9 , , PUNCT dti-1356 258 10 et et PROPN dti-1356 258 11 al al PROPN dti-1356 258 12 . . PUNCT dti-1356 258 13 esophageal esophageal ADJ dti-1356 258 14 dysmotility dysmotility NOUN dti-1356 258 15 is be AUX dti-1356 258 16 more more ADV dti-1356 258 17 common common ADJ dti-1356 258 18 than than ADP dti-1356 258 19 gastroparesis gastroparesis NOUN dti-1356 258 20 in in ADP dti-1356 258 21 diabetes diabetes NOUN dti-1356 258 22 mellitus mellitus NOUN dti-1356 258 23 and and CCONJ dti-1356 258 24 is be AUX dti-1356 258 25 associated associate VERB dti-1356 258 26 with with ADP dti-1356 258 27 retinopathy retinopathy NOUN dti-1356 258 28 . . PUNCT dti-1356 259 1 rev rev VERB dti-1356 259 2 diabet diabet NOUN dti-1356 259 3 stud stud NOUN dti-1356 259 4 . . PUNCT dti-1356 260 1 2011;8:258–265 2011;8:258–265 NUM dti-1356 260 2 . . NOUN dti-1356 261 1 27 27 NUM dti-1356 261 2 . . PUNCT dti-1356 262 1 cordeddu cordeddu PROPN dti-1356 262 2 l l NOUN dti-1356 262 3 , , PUNCT dti-1356 262 4 bergvall bergvall PROPN dti-1356 262 5 m m PRON dti-1356 262 6 , , PUNCT dti-1356 262 7 sand sand NOUN dti-1356 262 8 m m NOUN dti-1356 262 9 , , PUNCT dti-1356 262 10 roth roth PROPN dti-1356 262 11 b b PROPN dti-1356 262 12 , , PUNCT dti-1356 262 13 papadaki papadaki PROPN dti-1356 262 14 e e NOUN dti-1356 262 15 , , PUNCT dti-1356 262 16 li li PROPN dti-1356 262 17 l l PROPN dti-1356 262 18 , , PUNCT dti-1356 262 19 d’amato d’amato VERB dti-1356 262 20 m m PRON dti-1356 262 21 , , PUNCT dti-1356 262 22 ohlsson ohlsson PROPN dti-1356 262 23 b. b. PROPN dti-1356 262 24 severe severe ADJ dti-1356 262 25 , , PUNCT dti-1356 262 26 gastrointestinal gastrointestinal ADJ dti-1356 262 27 dysmotility dysmotility NOUN dti-1356 262 28 developed develop VERB dti-1356 262 29 after after ADP dti-1356 262 30 treatment treatment NOUN dti-1356 262 31 with with ADP dti-1356 262 32 gonadotropin gonadotropin NOUN dti-1356 262 33 - - PUNCT dti-1356 262 34 releasing release VERB dti-1356 262 35 hormone hormone NOUN dti-1356 262 36 analogs analog NOUN dti-1356 262 37 . . PUNCT dti-1356 263 1 scand scand PROPN dti-1356 263 2 j j PROPN dti-1356 263 3 gastroenterol gastroenterol PROPN dti-1356 263 4 . . PUNCT dti-1356 264 1 in in ADP dti-1356 264 2 press press NOUN dti-1356 264 3 2014 2014 NUM dti-1356 264 4 . . PUNCT dti-1356 265 1 28 28 NUM dti-1356 265 2 . . PUNCT dti-1356 266 1 klooker klooker PROPN dti-1356 266 2 tk tk PROPN dti-1356 266 3 , , PUNCT dti-1356 266 4 braak braak PROPN dti-1356 266 5 b b NUM dti-1356 266 6 , , PUNCT dti-1356 266 7 koopman koopman PROPN dti-1356 266 8 ke ke PROPN dti-1356 266 9 , , PUNCT dti-1356 266 10 et et PROPN dti-1356 266 11 al al PROPN dti-1356 266 12 . . PUNCT dti-1356 267 1 the the DET dti-1356 267 2 mast mast NOUN dti-1356 267 3 cell cell NOUN dti-1356 267 4 stabiliser stabiliser NOUN dti-1356 267 5 ketotifen ketotifen NOUN dti-1356 267 6 decreases decrease VERB dti-1356 267 7 visceral visceral ADJ dti-1356 267 8 hypersensitivity hypersensitivity NOUN dti-1356 267 9 and and CCONJ dti-1356 267 10 improves improve VERB dti-1356 267 11 intestinal intestinal ADJ dti-1356 267 12 symptoms symptom NOUN dti-1356 267 13 in in ADP dti-1356 267 14 patients patient NOUN dti-1356 267 15 with with ADP dti-1356 267 16 irritable irritable ADJ dti-1356 267 17 bowel bowel NOUN dti-1356 267 18 syndrome syndrome NOUN dti-1356 267 19 . . PUNCT dti-1356 268 1 gut gut NOUN dti-1356 268 2 . . PUNCT dti-1356 269 1 2010;59:1213–1221 2010;59:1213–1221 NOUN dti-1356 269 2 . . PUNCT dti-1356 270 1 29 29 NUM dti-1356 270 2 . . PUNCT dti-1356 271 1 sand sand NOUN dti-1356 271 2 e e NOUN dti-1356 271 3 , , PUNCT dti-1356 271 4 voss voss PROPN dti-1356 271 5 u u PROPN dti-1356 271 6 , , PUNCT dti-1356 271 7 hammar hammar PROPN dti-1356 271 8 o o PROPN dti-1356 271 9 , , PUNCT dti-1356 271 10 et et PROPN dti-1356 271 11 al al PROPN dti-1356 271 12 . . PUNCT dti-1356 272 1 gonadotropin gonadotropin NOUN dti-1356 272 2 - - PUNCT dti-1356 272 3 releasing release VERB dti-1356 272 4 hormone hormone NOUN dti-1356 272 5 analog analog NOUN dti-1356 272 6 buserelin buserelin PROPN dti-1356 272 7 causes cause VERB dti-1356 272 8 neuronal neuronal ADJ dti-1356 272 9 loss loss NOUN dti-1356 272 10 in in ADP dti-1356 272 11 rat rat NOUN dti-1356 272 12 gastrointestinal gastrointestinal ADJ dti-1356 272 13 tract tract NOUN dti-1356 272 14 . . PUNCT dti-1356 273 1 cell cell NOUN dti-1356 273 2 tissue tissue NOUN dti-1356 273 3 res re NOUN dti-1356 273 4 . . PUNCT dti-1356 274 1 2013;351 2013;351 NUM dti-1356 274 2 : : PUNCT dti-1356 274 3 521–534 521–534 NUM dti-1356 274 4 . . NOUN dti-1356 275 1 30 30 NUM dti-1356 275 2 . . X dti-1356 275 3 de de X dti-1356 275 4 giorgio giorgio PROPN dti-1356 275 5 r r PROPN dti-1356 275 6 , , PUNCT dti-1356 275 7 barbara barbara PROPN dti-1356 275 8 g. g. PROPN dti-1356 275 9 is be AUX dti-1356 275 10 irritable irritable ADJ dti-1356 275 11 bowel bowel NOUN dti-1356 275 12 syndrome syndrome NOUN dti-1356 275 13 an an DET dti-1356 275 14 inflammatory inflammatory ADJ dti-1356 275 15 disorder disorder NOUN dti-1356 275 16 ? ? PUNCT dti-1356 276 1 curr curr PROPN dti-1356 276 2 gastroenterol gastroenterol PROPN dti-1356 276 3 rep rep PROPN dti-1356 276 4 . . PROPN dti-1356 276 5 2008;10:385–390 2008;10:385–390 PROPN dti-1356 276 6 . . PUNCT dti-1356 277 1 31 31 NUM dti-1356 277 2 . . PUNCT dti-1356 277 3 öhman öhman PROPN dti-1356 277 4 l l PROPN dti-1356 277 5 , , PUNCT dti-1356 277 6 simrén simrén ADJ dti-1356 277 7 m. m. NOUN dti-1356 277 8 pathogenesis pathogenesis NOUN dti-1356 277 9 of of ADP dti-1356 277 10 ibs ib NOUN dti-1356 277 11 : : PUNCT dti-1356 277 12 role role NOUN dti-1356 277 13 of of ADP dti-1356 277 14 inflammation inflammation NOUN dti-1356 277 15 , , PUNCT dti-1356 277 16 immunity immunity NOUN dti-1356 277 17 and and CCONJ dti-1356 277 18 neuroimmune neuroimmune NOUN dti-1356 277 19 interactions interaction NOUN dti-1356 277 20 . . PUNCT dti-1356 278 1 nat nat PROPN dti-1356 278 2 rev rev PROPN dti-1356 278 3 gastroenterol gastroenterol NOUN dti-1356 278 4 hepatol hepatol ADJ dti-1356 278 5 . . PUNCT dti-1356 279 1 2010;7:163–173 2010;7:163–173 NUM dti-1356 279 2 . . NOUN dti-1356 280 1 32 32 NUM dti-1356 280 2 . . PUNCT dti-1356 281 1 elsenbruch elsenbruch PROPN dti-1356 281 2 s s PROPN dti-1356 281 3 , , PUNCT dti-1356 281 4 rosenberger rosenberger PROPN dti-1356 281 5 c c PROPN dti-1356 281 6 , , PUNCT dti-1356 281 7 enck enck ADV dti-1356 281 8 p p X dti-1356 281 9 , , PUNCT dti-1356 281 10 forsting forste VERB dti-1356 281 11 m m PROPN dti-1356 281 12 , , PUNCT dti-1356 281 13 schedlowski schedlowski PROPN dti-1356 281 14 m m PROPN dti-1356 281 15 , , PUNCT dti-1356 281 16 gizewski gizewski PROPN dti-1356 281 17 er er INTJ dti-1356 281 18 . . PUNCT dti-1356 281 19 affective affective ADJ dti-1356 281 20 disturbances disturbance NOUN dti-1356 281 21 modulate modulate VERB dti-1356 281 22 the the DET dti-1356 281 23 neural neural ADJ dti-1356 281 24 processing processing NOUN dti-1356 281 25 of of ADP dti-1356 281 26 visceral visceral ADJ dti-1356 281 27 pain pain NOUN dti-1356 281 28 stimuli stimulus NOUN dti-1356 281 29 in in ADP dti-1356 281 30 irritable irritable ADJ dti-1356 281 31 bowel bowel NOUN dti-1356 281 32 syndrome syndrome NOUN dti-1356 281 33 : : PUNCT dti-1356 281 34 an an DET dti-1356 281 35 fmri fmri PROPN dti-1356 281 36 study study NOUN dti-1356 281 37 . . PUNCT dti-1356 282 1 gut gut NOUN dti-1356 282 2 . . PUNCT dti-1356 283 1 2010;59:489–495 2010;59:489–495 ADJ dti-1356 283 2 . . PUNCT dti-1356 284 1 33 33 NUM dti-1356 284 2 . . PUNCT dti-1356 285 1 larsson larsson PROPN dti-1356 285 2 mb mb PROPN dti-1356 285 3 , , PUNCT dti-1356 285 4 tillisch tillisch PROPN dti-1356 285 5 k k PROPN dti-1356 285 6 , , PUNCT dti-1356 285 7 craig craig PROPN dti-1356 285 8 ad ad PROPN dti-1356 285 9 , , PUNCT dti-1356 285 10 et et PROPN dti-1356 285 11 al al PROPN dti-1356 285 12 . . PUNCT dti-1356 285 13 brain brain NOUN dti-1356 285 14 responses response NOUN dti-1356 285 15 to to ADP dti-1356 285 16 visceral visceral ADJ dti-1356 285 17 stimuli stimulus NOUN dti-1356 285 18 reflect reflect VERB dti-1356 285 19 visceral visceral ADJ dti-1356 285 20 sensitivity sensitivity NOUN dti-1356 285 21 thresholds threshold NOUN dti-1356 285 22 in in ADP dti-1356 285 23 patients patient NOUN dti-1356 285 24 with with ADP dti-1356 285 25 irritable irritable ADJ dti-1356 285 26 bowel bowel NOUN dti-1356 285 27 syndrome syndrome NOUN dti-1356 285 28 . . PUNCT dti-1356 286 1 gastroenterology gastroenterology NOUN dti-1356 286 2 . . PUNCT dti-1356 287 1 2012;142:463.e–472.e 2012;142:463.e–472.e X dti-1356 287 2 . . PUNCT dti-1356 288 1 34 34 NUM dti-1356 288 2 . . PUNCT dti-1356 289 1 naor naor PROPN dti-1356 289 2 z. z. PROPN dti-1356 289 3 signaling signal VERB dti-1356 289 4 by by ADP dti-1356 289 5 g g NOUN dti-1356 289 6 - - PUNCT dti-1356 289 7 protein protein NOUN dti-1356 289 8 - - PUNCT dti-1356 289 9 coupled couple VERB dti-1356 289 10 receptor receptor NOUN dti-1356 289 11 ( ( PUNCT dti-1356 289 12 gpcr gpcr ADJ dti-1356 289 13 ): ): PUNCT dti-1356 289 14 studies study NOUN dti-1356 289 15 on on ADP dti-1356 289 16 the the DET dti-1356 289 17 gnrh gnrh NOUN dti-1356 289 18 receptor receptor NOUN dti-1356 289 19 . . PUNCT dti-1356 290 1 front front ADJ dti-1356 290 2 neuroendocrinol neuroendocrinol NOUN dti-1356 290 3 . . PUNCT dti-1356 291 1 2009;30:10–29 2009;30:10–29 NUM dti-1356 291 2 . . X dti-1356 292 1 35 35 NUM dti-1356 292 2 . . PUNCT dti-1356 292 3 soldani soldani PROPN dti-1356 292 4 g g PROPN dti-1356 292 5 , , PUNCT dti-1356 292 6 del del X dti-1356 292 7 tacca tacca NOUN dti-1356 292 8 mm mm PROPN dti-1356 292 9 , , PUNCT dti-1356 292 10 bambini bambini NOUN dti-1356 292 11 g g PROPN dti-1356 292 12 , , PUNCT dti-1356 292 13 et et PROPN dti-1356 292 14 al al PROPN dti-1356 292 15 . . PUNCT dti-1356 293 1 effects effect NOUN dti-1356 293 2 of of ADP dti-1356 293 3 gonadotropin gonadotropin NOUN dti-1356 293 4 - - PUNCT dti-1356 293 5 releasing release VERB dti-1356 293 6 hormone hormone NOUN dti-1356 293 7 ( ( PUNCT dti-1356 293 8 gnrh gnrh NOUN dti-1356 293 9 ) ) PUNCT dti-1356 293 10 on on ADP dti-1356 293 11 gastric gastric ADJ dti-1356 293 12 secretion secretion NOUN dti-1356 293 13 and and CCONJ dti-1356 293 14 gastrin gastrin NOUN dti-1356 293 15 release release NOUN dti-1356 293 16 in in ADP dti-1356 293 17 the the DET dti-1356 293 18 dog dog NOUN dti-1356 293 19 . . PUNCT dti-1356 294 1 drug drug NOUN dti-1356 294 2 metab metab PROPN dti-1356 294 3 dispos dispos PROPN dti-1356 294 4 . . PUNCT dti-1356 295 1 1993;21:818–822 1993;21:818–822 NOUN dti-1356 295 2 . . PUNCT dti-1356 296 1 36 36 NUM dti-1356 296 2 . . PUNCT dti-1356 297 1 meyer meyer PROPN dti-1356 297 2 wr wr PROPN dti-1356 297 3 , , PUNCT dti-1356 297 4 lavy lavy PROPN dti-1356 297 5 g g PROPN dti-1356 297 6 , , PUNCT dti-1356 297 7 decherney decherney PROPN dti-1356 297 8 ah ah INTJ dti-1356 297 9 , , PUNCT dti-1356 297 10 visintin visintin PROPN dti-1356 297 11 i i PRON dti-1356 297 12 , , PUNCT dti-1356 297 13 economy economy NOUN dti-1356 297 14 k k PROPN dti-1356 297 15 , , PUNCT dti-1356 297 16 luborsky luborsky PROPN dti-1356 297 17 jl jl PROPN dti-1356 297 18 . . PUNCT dti-1356 297 19 evidence evidence NOUN dti-1356 297 20 of of ADP dti-1356 297 21 gonadal gonadal NOUN dti-1356 297 22 and and CCONJ dti-1356 297 23 gonadotropin gonadotropin NOUN dti-1356 297 24 antibodies antibodie VERB dti-1356 297 25 in in ADP dti-1356 297 26 women woman NOUN dti-1356 297 27 with with ADP dti-1356 297 28 a a DET dti-1356 297 29 suboptimal suboptimal ADJ dti-1356 297 30 ovarian ovarian ADJ dti-1356 297 31 response response NOUN dti-1356 297 32 to to PART dti-1356 297 33 exogenous exogenous VERB dti-1356 297 34 gonadotropin gonadotropin NOUN dti-1356 297 35 . . PUNCT dti-1356 298 1 obstet obstet PROPN dti-1356 298 2 gynecol gynecol PROPN dti-1356 298 3 . . PUNCT dti-1356 299 1 1990;75:795–799 1990;75:795–799 PROPN dti-1356 299 2 . . PROPN dti-1356 300 1 37 37 NUM dti-1356 300 2 . . PUNCT dti-1356 301 1 wald wald PROPN dti-1356 301 2 a a X dti-1356 301 3 , , PUNCT dti-1356 301 4 van van PROPN dti-1356 301 5 thiel thiel PROPN dti-1356 301 6 dh dh PROPN dti-1356 301 7 , , PUNCT dti-1356 301 8 hoechstetter hoechstetter PROPN dti-1356 301 9 l l PROPN dti-1356 301 10 , , PUNCT dti-1356 301 11 et et PROPN dti-1356 301 12 al al PROPN dti-1356 301 13 . . PUNCT dti-1356 301 14 gastrointestinal gastrointestinal ADJ dti-1356 301 15 transit transit PROPN dti-1356 301 16 : : PUNCT dti-1356 301 17 the the DET dti-1356 301 18 effect effect NOUN dti-1356 301 19 of of ADP dti-1356 301 20 the the DET dti-1356 301 21 menstrual menstrual ADJ dti-1356 301 22 cycle cycle NOUN dti-1356 301 23 . . PUNCT dti-1356 302 1 gastroenterology gastroenterology NOUN dti-1356 302 2 . . PUNCT dti-1356 303 1 1981;80:1497–1500 1981;80:1497–1500 NUM dti-1356 303 2 . . PUNCT dti-1356 304 1 38 38 NUM dti-1356 304 2 . . PUNCT dti-1356 305 1 mathias mathias PROPN dti-1356 305 2 jr jr PROPN dti-1356 305 3 , , PUNCT dti-1356 305 4 franklin franklin PROPN dti-1356 305 5 r r PROPN dti-1356 305 6 , , PUNCT dti-1356 305 7 quast quast VERB dti-1356 305 8 dc dc PROPN dti-1356 305 9 , , PUNCT dti-1356 305 10 et et PROPN dti-1356 305 11 al al PROPN dti-1356 305 12 . . PUNCT dti-1356 305 13 relation relation NOUN dti-1356 305 14 of of ADP dti-1356 305 15 endometriosis endometriosis NOUN dti-1356 305 16 and and CCONJ dti-1356 305 17 neuromuscular neuromuscular ADJ dti-1356 305 18 disease disease NOUN dti-1356 305 19 of of ADP dti-1356 305 20 the the DET dti-1356 305 21 gastrointestinal gastrointestinal ADJ dti-1356 305 22 tract tract NOUN dti-1356 305 23 : : PUNCT dti-1356 306 1 new new ADJ dti-1356 306 2 insights insight NOUN dti-1356 306 3 . . PUNCT dti-1356 307 1 fertil fertil PROPN dti-1356 307 2 steril steril PROPN dti-1356 307 3 . . PROPN dti-1356 308 1 1998;70:81–88 1998;70:81–88 NUM dti-1356 308 2 . . X dti-1356 309 1 39 39 NUM dti-1356 309 2 . . PUNCT dti-1356 310 1 gonenne gonenne PROPN dti-1356 310 2 j j PROPN dti-1356 310 3 , , PUNCT dti-1356 310 4 esfandyari esfandyari PROPN dti-1356 310 5 t t PROPN dti-1356 310 6 , , PUNCT dti-1356 310 7 camilleri camilleri PROPN dti-1356 310 8 m m PROPN dti-1356 310 9 , , PUNCT dti-1356 310 10 et et PROPN dti-1356 310 11 al al PROPN dti-1356 310 12 . . PROPN dti-1356 310 13 effect effect NOUN dti-1356 310 14 of of ADP dti-1356 310 15 female female ADJ dti-1356 310 16 sex sex NOUN dti-1356 310 17 hormone hormone NOUN dti-1356 310 18 supplementation supplementation NOUN dti-1356 310 19 and and CCONJ dti-1356 310 20 withdrawal withdrawal NOUN dti-1356 310 21 on on ADP dti-1356 310 22 gastrointestinal gastrointestinal ADJ dti-1356 310 23 and and CCONJ dti-1356 310 24 colonic colonic ADJ dti-1356 310 25 transit transit NOUN dti-1356 310 26 in in ADP dti-1356 310 27 postmenopausal postmenopausal ADJ dti-1356 310 28 women woman NOUN dti-1356 310 29 . . PUNCT dti-1356 311 1 neurogastroenterol neurogastroenterol PROPN dti-1356 311 2 motil motil PROPN dti-1356 311 3 . . PUNCT dti-1356 312 1 2006;18:911–918 2006;18:911–918 PROPN dti-1356 312 2 . . PUNCT dti-1356 313 1 http://www.la-press.com http://www.la-press.com X dti-1356 313 2 http://www.la-press.com/drug-target-insights-journal-j23 http://www.la-press.com/drug-target-insights-journal-j23 PROPN