id sid tid token lemma pos dti-1406 1 1 1drug 1drug NUM dti-1406 1 2 target target NOUN dti-1406 1 3 insights insight NOUN dti-1406 1 4 2015:9 2015:9 DET dti-1406 1 5 7 7 NUM dti-1406 1 6 - - PUNCT dti-1406 1 7 ni ni NOUN dti-1406 1 8 and and CCONJ dti-1406 1 9 odq odq NOUN dti-1406 1 10 disturbs disturb VERB dti-1406 1 11 memory memory NOUN dti-1406 1 12 in in ADP dti-1406 1 13 the the DET dti-1406 1 14 elevated elevated ADJ dti-1406 1 15 plus plus CCONJ dti-1406 1 16 maze maze NOUN dti-1406 1 17 , , PUNCT dti-1406 1 18 morris morris PROPN dti-1406 1 19 water water NOUN dti-1406 1 20 maze maze NOUN dti-1406 1 21 , , PUNCT dti-1406 1 22 and and CCONJ dti-1406 1 23 radial radial ADJ dti-1406 1 24 arm arm NOUN dti-1406 1 25 maze maze NOUN dti-1406 1 26 tests test NOUN dti-1406 1 27 in in ADP dti-1406 1 28 mice mice NOUN dti-1406 1 29 oguz oguz PROPN dti-1406 1 30 mutlu1 mutlu1 PROPN dti-1406 1 31 , , PUNCT dti-1406 1 32 furuzan furuzan PROPN dti-1406 1 33 akar1 akar1 PROPN dti-1406 1 34 , , PUNCT dti-1406 1 35 ipek ipek PROPN dti-1406 1 36 komsuoglu komsuoglu PROPN dti-1406 1 37 celikyurt1 celikyurt1 PROPN dti-1406 1 38 , , PUNCT dti-1406 1 39 pelin pelin PROPN dti-1406 1 40 tanyeri2 tanyeri2 PROPN dti-1406 1 41 , , PUNCT dti-1406 1 42 guner guner NOUN dti-1406 1 43 ulak1 ulak1 PROPN dti-1406 1 44 and and CCONJ dti-1406 1 45 faruk faruk PROPN dti-1406 1 46 erden1 erden1 VERB dti-1406 2 1 1department 1department NUM dti-1406 2 2 of of ADP dti-1406 2 3 pharmacology pharmacology NOUN dti-1406 2 4 , , PUNCT dti-1406 2 5 kocaeli kocaeli VERB dti-1406 2 6 university university PROPN dti-1406 2 7 medical medical ADJ dti-1406 2 8 faculty faculty NOUN dti-1406 2 9 , , PUNCT dti-1406 2 10 kocaeli kocaeli PROPN dti-1406 2 11 , , PUNCT dti-1406 2 12 turkey turkey PROPN dti-1406 2 13 . . PUNCT dti-1406 3 1 2department 2department NUM dti-1406 3 2 of of ADP dti-1406 3 3 pharmacology pharmacology NOUN dti-1406 3 4 , , PUNCT dti-1406 3 5 faculty faculty NOUN dti-1406 3 6 of of ADP dti-1406 3 7 medicine medicine NOUN dti-1406 3 8 , , PUNCT dti-1406 3 9 sakarya sakarya NOUN dti-1406 3 10 university university NOUN dti-1406 3 11 , , PUNCT dti-1406 3 12 sakarya sakarya NOUN dti-1406 3 13 , , PUNCT dti-1406 3 14 turkey turkey PROPN dti-1406 3 15 . . PUNCT dti-1406 4 1 abstr abstr PROPN dti-1406 4 2 act act PROPN dti-1406 4 3 : : PUNCT dti-1406 4 4 nitric nitric ADJ dti-1406 4 5 oxide oxide NOUN dti-1406 4 6 ( ( PUNCT dti-1406 4 7 no no NOUN dti-1406 4 8 ) ) PUNCT dti-1406 4 9 is be AUX dti-1406 4 10 an an DET dti-1406 4 11 atypical atypical ADJ dti-1406 4 12 neurotransmitter neurotransmitter NOUN dti-1406 4 13 that that PRON dti-1406 4 14 causes cause VERB dti-1406 4 15 changes change NOUN dti-1406 4 16 in in ADP dti-1406 4 17 cognition cognition NOUN dti-1406 4 18 . . PUNCT dti-1406 5 1 nitric nitric ADJ dti-1406 5 2 oxide oxide NOUN dti-1406 5 3 synthase synthase NOUN dti-1406 5 4 ( ( PUNCT dti-1406 5 5 nos nos NOUN dti-1406 5 6 ) ) PUNCT dti-1406 5 7 and and CCONJ dti-1406 5 8 guanylate guanylate NOUN dti-1406 5 9 cyclase cyclase NOUN dti-1406 5 10 ( ( PUNCT dti-1406 5 11 gc gc PROPN dti-1406 5 12 ) ) PUNCT dti-1406 5 13 inhibitors inhibitor NOUN dti-1406 5 14 have have AUX dti-1406 5 15 been be AUX dti-1406 5 16 shown show VERB dti-1406 5 17 to to PART dti-1406 5 18 exert exert VERB dti-1406 5 19 some some DET dti-1406 5 20 effects effect NOUN dti-1406 5 21 on on ADP dti-1406 5 22 cognition cognition NOUN dti-1406 5 23 in in ADP dti-1406 5 24 previous previous ADJ dti-1406 5 25 studies study NOUN dti-1406 5 26 ; ; PUNCT dti-1406 5 27 however however ADV dti-1406 5 28 , , PUNCT dti-1406 5 29 the the DET dti-1406 5 30 findings finding NOUN dti-1406 5 31 have have AUX dti-1406 5 32 been be AUX dti-1406 5 33 controversial controversial ADJ dti-1406 5 34 . . PUNCT dti-1406 6 1 this this DET dti-1406 6 2 study study NOUN dti-1406 6 3 was be AUX dti-1406 6 4 aimed aim VERB dti-1406 6 5 at at ADP dti-1406 6 6 understanding understand VERB dti-1406 6 7 the the DET dti-1406 6 8 effects effect NOUN dti-1406 6 9 of of ADP dti-1406 6 10 an an DET dti-1406 6 11 nos nos X dti-1406 6 12 inhibitor inhibitor NOUN dti-1406 6 13 , , PUNCT dti-1406 6 14 7 7 NUM dti-1406 6 15 - - PUNCT dti-1406 6 16 nitroindazole nitroindazole NOUN dti-1406 6 17 ( ( PUNCT dti-1406 6 18 7 7 NUM dti-1406 6 19 - - PUNCT dti-1406 6 20 ni ni NOUN dti-1406 6 21 ) ) PUNCT dti-1406 6 22 , , PUNCT dti-1406 6 23 and and CCONJ dti-1406 6 24 a a DET dti-1406 6 25 guanylate guanylate NOUN dti-1406 6 26 cyclase cyclase NOUN dti-1406 6 27 inhibitor inhibitor NOUN dti-1406 6 28 , , PUNCT dti-1406 6 29 1h-[1,2,4]oxadiazolo[4,3 1h-[1,2,4]oxadiazolo[4,3 PROPN dti-1406 6 30 - - PUNCT dti-1406 6 31 a]quinoxalin-1 a]quinoxalin-1 NOUN dti-1406 6 32 - - PUNCT dti-1406 6 33 one one NUM dti-1406 6 34 ( ( PUNCT dti-1406 6 35 odq odq NOUN dti-1406 6 36 ) ) PUNCT dti-1406 6 37 , , PUNCT dti-1406 6 38 on on ADP dti-1406 6 39 spatial spatial ADJ dti-1406 6 40 memory memory NOUN dti-1406 6 41 in in ADP dti-1406 6 42 modified modify VERB dti-1406 6 43 elevated elevated ADJ dti-1406 6 44 plus plus CCONJ dti-1406 6 45 maze maze NOUN dti-1406 6 46 ( ( PUNCT dti-1406 6 47 mepm mepm NOUN dti-1406 6 48 ) ) PUNCT dti-1406 6 49 , , PUNCT dti-1406 6 50 morris morris PROPN dti-1406 6 51 water water PROPN dti-1406 6 52 maze maze NOUN dti-1406 6 53 ( ( PUNCT dti-1406 6 54 mwm mwm NOUN dti-1406 6 55 ) ) PUNCT dti-1406 6 56 , , PUNCT dti-1406 6 57 and and CCONJ dti-1406 6 58 radial radial ADJ dti-1406 6 59 arm arm NOUN dti-1406 6 60 maze maze NOUN dti-1406 6 61 ( ( PUNCT dti-1406 6 62 ram ram NOUN dti-1406 6 63 ) ) PUNCT dti-1406 6 64 tests test NOUN dti-1406 6 65 . . PUNCT dti-1406 7 1 male male ADJ dti-1406 7 2 balb balb ADJ dti-1406 7 3 - - PUNCT dti-1406 7 4 c c NOUN dti-1406 7 5 mice mouse NOUN dti-1406 7 6 were be AUX dti-1406 7 7 treated treat VERB dti-1406 7 8 via via ADP dti-1406 7 9 intraperitoneal intraperitoneal ADJ dti-1406 7 10 injections injection NOUN dti-1406 7 11 with with ADP dti-1406 7 12 7 7 NUM dti-1406 7 13 - - PUNCT dti-1406 7 14 ni ni NOUN dti-1406 7 15 ( ( PUNCT dti-1406 7 16 15 15 NUM dti-1406 7 17     SPACE dti-1406 7 18 mg mg PROPN dti-1406 7 19 / / SYM dti-1406 7 20 kg kg PROPN dti-1406 7 21 ) ) PUNCT dti-1406 7 22 , , PUNCT dti-1406 7 23 odq odq PROPN dti-1406 7 24 ( ( PUNCT dti-1406 7 25 3 3 NUM dti-1406 7 26 , , PUNCT dti-1406 7 27 10 10 NUM dti-1406 7 28     SPACE dti-1406 7 29 mg mg PROPN dti-1406 7 30 / / SYM dti-1406 7 31 kg kg PROPN dti-1406 7 32 ) ) PUNCT dti-1406 7 33 , , PUNCT dti-1406 7 34 l l NOUN dti-1406 7 35 - - NOUN dti-1406 7 36 arginine arginine NOUN dti-1406 7 37 ( ( PUNCT dti-1406 7 38 100 100 NUM dti-1406 7 39     SPACE dti-1406 7 40 mg mg PROPN dti-1406 7 41 / / SYM dti-1406 7 42 kg kg NOUN dti-1406 7 43 ) ) PUNCT dti-1406 8 1 + + CCONJ dti-1406 8 2 7 7 NUM dti-1406 8 3 - - PUNCT dti-1406 8 4 ni ni NOUN dti-1406 8 5 ( ( PUNCT dti-1406 8 6 15 15 NUM dti-1406 8 7     SPACE dti-1406 8 8 mg mg PROPN dti-1406 8 9 / / SYM dti-1406 8 10 kg kg PROPN dti-1406 8 11 ) ) PUNCT dti-1406 8 12 , , PUNCT dti-1406 8 13 or or CCONJ dti-1406 8 14 physiological physiological ADJ dti-1406 8 15 saline saline NOUN dti-1406 8 16 . . PUNCT dti-1406 9 1 odq odq NOUN dti-1406 9 2 ( ( PUNCT dti-1406 9 3 3 3 NUM dti-1406 9 4     SPACE dti-1406 9 5 mg mg PROPN dti-1406 9 6 / / SYM dti-1406 9 7 kg kg PROPN dti-1406 9 8 ) ) PUNCT dti-1406 9 9 and and CCONJ dti-1406 9 10 7 7 NUM dti-1406 9 11 - - PUNCT dti-1406 9 12 ni ni PROPN dti-1406 9 13 ( ( PUNCT dti-1406 9 14 15 15 NUM dti-1406 9 15     SPACE dti-1406 9 16 mg mg PROPN dti-1406 9 17 / / SYM dti-1406 9 18 kg kg NOUN dti-1406 9 19 ) ) PUNCT dti-1406 9 20 significantly significantly ADV dti-1406 9 21 increased increase VERB dti-1406 9 22 the the DET dti-1406 9 23 second second ADJ dti-1406 9 24 - - PUNCT dti-1406 9 25 day day NOUN dti-1406 9 26 latency latency NOUN dti-1406 9 27 in in ADP dti-1406 9 28 the the DET dti-1406 9 29 mepm mepm NOUN dti-1406 9 30 test test NOUN dti-1406 9 31 . . PUNCT dti-1406 10 1 7 7 NUM dti-1406 10 2 - - SYM dti-1406 10 3 ni ni PROPN dti-1406 10 4 ( ( PUNCT dti-1406 10 5 15 15 NUM dti-1406 10 6     SPACE dti-1406 10 7 mg mg PROPN dti-1406 10 8 / / SYM dti-1406 10 9 kg kg PROPN dti-1406 10 10 ) ) PUNCT dti-1406 10 11 and and CCONJ dti-1406 10 12 odq odq NOUN dti-1406 10 13 ( ( PUNCT dti-1406 10 14 10 10 NUM dti-1406 10 15     SPACE dti-1406 10 16 mg mg PROPN dti-1406 10 17 / / SYM dti-1406 10 18 kg kg NOUN dti-1406 10 19 ) ) PUNCT dti-1406 10 20 significantly significantly ADV dti-1406 10 21 increased increase VERB dti-1406 10 22 the the DET dti-1406 10 23 escape escape NOUN dti-1406 10 24 latency latency NOUN dti-1406 10 25 in in ADP dti-1406 10 26 second second ADJ dti-1406 10 27 , , PUNCT dti-1406 10 28 third third ADJ dti-1406 10 29 , , PUNCT dti-1406 10 30 and and CCONJ dti-1406 10 31 fourth fourth ADJ dti-1406 10 32 sessions session NOUN dti-1406 10 33 , , PUNCT dti-1406 10 34 decreased decrease VERB dti-1406 10 35 the the DET dti-1406 10 36 time time NOUN dti-1406 10 37 spent spend VERB dti-1406 10 38 in in ADP dti-1406 10 39 the the DET dti-1406 10 40 escape escape NOUN dti-1406 10 41 platform platform NOUN dti-1406 10 42 ’s ’s PART dti-1406 10 43 quadrant quadrant NOUN dti-1406 10 44 , , PUNCT dti-1406 10 45 and and CCONJ dti-1406 10 46 increased increase VERB dti-1406 10 47 the the DET dti-1406 10 48 mean mean ADJ dti-1406 10 49 distance distance NOUN dti-1406 10 50 to to ADP dti-1406 10 51 the the DET dti-1406 10 52 platform platform NOUN dti-1406 10 53 in in ADP dti-1406 10 54 the the DET dti-1406 10 55 probe probe NOUN dti-1406 10 56 trial trial NOUN dti-1406 10 57 of of ADP dti-1406 10 58 the the DET dti-1406 10 59 mwm mwm NOUN dti-1406 10 60 test test NOUN dti-1406 10 61 . . PUNCT dti-1406 11 1 odq odq NOUN dti-1406 11 2 ( ( PUNCT dti-1406 11 3 3 3 NUM dti-1406 11 4 , , PUNCT dti-1406 11 5 10 10 NUM dti-1406 11 6     SPACE dti-1406 11 7 mg mg PROPN dti-1406 11 8 / / SYM dti-1406 11 9 kg kg PROPN dti-1406 11 10 ) ) PUNCT dti-1406 11 11 and and CCONJ dti-1406 11 12 7 7 NUM dti-1406 11 13 - - PUNCT dti-1406 11 14 ni ni PROPN dti-1406 11 15 ( ( PUNCT dti-1406 11 16 15 15 NUM dti-1406 11 17     SPACE dti-1406 11 18 mg mg PROPN dti-1406 11 19 / / SYM dti-1406 11 20 kg kg NOUN dti-1406 11 21 ) ) PUNCT dti-1406 11 22 significantly significantly ADV dti-1406 11 23 increased increase VERB dti-1406 11 24 the the DET dti-1406 11 25 number number NOUN dti-1406 11 26 of of ADP dti-1406 11 27 errors error NOUN dti-1406 11 28 , , PUNCT dti-1406 11 29 whereas whereas SCONJ dti-1406 11 30 only only ADV dti-1406 11 31 7 7 NUM dti-1406 11 32 - - SYM dti-1406 11 33 ni ni PROPN dti-1406 11 34 increased increase VERB dti-1406 11 35 the the DET dti-1406 11 36 latency latency NOUN dti-1406 11 37 in in ADP dti-1406 11 38 the the DET dti-1406 11 39 ram ram NOUN dti-1406 11 40 test test NOUN dti-1406 11 41 . . PUNCT dti-1406 12 1 the the DET dti-1406 12 2 administration administration NOUN dti-1406 12 3 of of ADP dti-1406 12 4 l l NOUN dti-1406 12 5 - - NOUN dti-1406 12 6 arginine arginine NOUN dti-1406 12 7 ( ( PUNCT dti-1406 12 8 100 100 NUM dti-1406 12 9     SPACE dti-1406 12 10 mg mg PROPN dti-1406 12 11 / / SYM dti-1406 12 12 kg kg PROPN dti-1406 12 13 ) ) PUNCT dti-1406 12 14 prior prior ADV dti-1406 12 15 to to ADP dti-1406 12 16 7 7 NUM dti-1406 12 17 - - PUNCT dti-1406 12 18 ni ni NOUN dti-1406 12 19 inverted invert VERB dti-1406 12 20 the the DET dti-1406 12 21 effects effect NOUN dti-1406 12 22 of of ADP dti-1406 12 23 7 7 NUM dti-1406 12 24 - - PUNCT dti-1406 12 25 ni ni NOUN dti-1406 12 26 , , PUNCT dti-1406 12 27 which which PRON dti-1406 12 28 supports support VERB dti-1406 12 29 the the DET dti-1406 12 30 role role NOUN dti-1406 12 31 of of ADP dti-1406 12 32 no no PRON dti-1406 12 33 on on ADP dti-1406 12 34 cognition cognition NOUN dti-1406 12 35 . . PUNCT dti-1406 13 1 our our PRON dti-1406 13 2 study study NOUN dti-1406 13 3 shows show VERB dti-1406 13 4 that that SCONJ dti-1406 13 5 the the DET dti-1406 13 6 no no NOUN dti-1406 13 7 / / SYM dti-1406 13 8 cgmp cgmp NOUN dti-1406 13 9 / / SYM dti-1406 13 10 gs gs NOUN dti-1406 13 11 pathway pathway NOUN dti-1406 13 12 can can AUX dti-1406 13 13 regulate regulate VERB dti-1406 13 14 spatial spatial ADJ dti-1406 13 15 memory memory NOUN dti-1406 13 16 in in ADP dti-1406 13 17 mice mouse NOUN dti-1406 13 18 . . PUNCT dti-1406 14 1 key key ADJ dti-1406 14 2 words word NOUN dti-1406 14 3 : : PUNCT dti-1406 14 4 7 7 NUM dti-1406 14 5 - - PUNCT dti-1406 14 6 ni ni PROPN dti-1406 14 7 , , PUNCT dti-1406 14 8 odq odq NOUN dti-1406 14 9 , , PUNCT dti-1406 14 10 memory memory NOUN dti-1406 14 11 , , PUNCT dti-1406 14 12 mice mouse NOUN dti-1406 14 13 citation citation NOUN dti-1406 14 14 : : PUNCT dti-1406 14 15 mutlu mutlu PROPN dti-1406 14 16 et et PROPN dti-1406 14 17 al al PROPN dti-1406 14 18 . . PROPN dti-1406 15 1 7 7 PROPN dti-1406 15 2 - - PUNCT dti-1406 15 3 ni ni NOUN dti-1406 15 4 and and CCONJ dti-1406 15 5 odq odq NOUN dti-1406 15 6 disturbs disturb VERB dti-1406 15 7 memory memory NOUN dti-1406 15 8 in in ADP dti-1406 15 9 the the DET dti-1406 15 10 elevated elevated ADJ dti-1406 15 11 plus plus CCONJ dti-1406 15 12 maze maze NOUN dti-1406 15 13 , , PUNCT dti-1406 15 14 morris morris PROPN dti-1406 15 15 water water NOUN dti-1406 15 16 maze maze NOUN dti-1406 15 17 , , PUNCT dti-1406 15 18 and and CCONJ dti-1406 15 19 radial radial ADJ dti-1406 15 20 arm arm NOUN dti-1406 15 21 maze maze NOUN dti-1406 15 22 tests test NOUN dti-1406 15 23 in in ADP dti-1406 15 24 mice mouse NOUN dti-1406 15 25 . . PUNCT dti-1406 16 1 drug drug NOUN dti-1406 16 2 target target NOUN dti-1406 16 3 insights insight VERB dti-1406 16 4 2015:9 2015:9 PRON dti-1406 16 5 1–8 1–8 NUM dti-1406 16 6 doi:10.4137 doi:10.4137 NOUN dti-1406 16 7 / / SYM dti-1406 16 8 dti.s23378 dti.s23378 X dti-1406 16 9 . . PUNCT dti-1406 17 1 received receive VERB dti-1406 17 2 : : PUNCT dti-1406 17 3 january january PROPN dti-1406 17 4 9 9 NUM dti-1406 17 5 , , PUNCT dti-1406 17 6 2015 2015 NUM dti-1406 17 7 . . PUNCT dti-1406 18 1 resubmitted resubmitte VERB dti-1406 18 2 : : PUNCT dti-1406 18 3 february february PROPN dti-1406 18 4 2 2 NUM dti-1406 18 5 , , PUNCT dti-1406 18 6 2015 2015 NUM dti-1406 18 7 . . PUNCT dti-1406 19 1 accepted accept VERB dti-1406 19 2 for for ADP dti-1406 19 3 publication publication NOUN dti-1406 19 4 : : PUNCT dti-1406 19 5 february february PROPN dti-1406 19 6 10 10 NUM dti-1406 19 7 , , PUNCT dti-1406 19 8 2015 2015 NUM dti-1406 19 9 . . PUNCT dti-1406 20 1 academic academic ADJ dti-1406 20 2 editor editor NOUN dti-1406 20 3 : : PUNCT dti-1406 20 4 anuj anuj PROPN dti-1406 20 5 chauhan chauhan PROPN dti-1406 20 6 , , PUNCT dti-1406 20 7 editor editor NOUN dti-1406 20 8 in in ADP dti-1406 20 9 chief chief ADJ dti-1406 20 10 type type NOUN dti-1406 20 11 : : PUNCT dti-1406 20 12 original original ADJ dti-1406 20 13 research research NOUN dti-1406 20 14 funding funding NOUN dti-1406 20 15 : : PUNCT dti-1406 20 16 authors author NOUN dti-1406 20 17 disclose disclose VERB dti-1406 20 18 no no DET dti-1406 20 19 funding funding NOUN dti-1406 20 20 sources source NOUN dti-1406 20 21 . . PUNCT dti-1406 21 1 competing compete VERB dti-1406 21 2 interests interest NOUN dti-1406 21 3 : : PUNCT dti-1406 21 4 authors author NOUN dti-1406 21 5 disclose disclose VERB dti-1406 21 6 no no DET dti-1406 21 7 potential potential ADJ dti-1406 21 8 conflicts conflict NOUN dti-1406 21 9 of of ADP dti-1406 21 10 interest interest NOUN dti-1406 21 11 . . PUNCT dti-1406 22 1 copyright copyright NOUN dti-1406 22 2 : : PUNCT dti-1406 22 3 © © PROPN dti-1406 22 4 the the DET dti-1406 22 5 authors author NOUN dti-1406 22 6 , , PUNCT dti-1406 22 7 publisher publisher NOUN dti-1406 22 8 and and CCONJ dti-1406 22 9 licensee licensee NOUN dti-1406 22 10 libertas liberta NOUN dti-1406 22 11 academica academica PROPN dti-1406 22 12 limited limit VERB dti-1406 22 13 . . PUNCT dti-1406 23 1 this this PRON dti-1406 23 2 is be AUX dti-1406 23 3 an an DET dti-1406 23 4 open open ADJ dti-1406 23 5 - - PUNCT dti-1406 23 6 access access NOUN dti-1406 23 7 article article NOUN dti-1406 23 8 distributed distribute VERB dti-1406 23 9 under under ADP dti-1406 23 10 the the DET dti-1406 23 11 terms term NOUN dti-1406 23 12 of of ADP dti-1406 23 13 the the DET dti-1406 23 14 creative creative ADJ dti-1406 23 15 commons common NOUN dti-1406 23 16 cc cc NOUN dti-1406 23 17 - - PUNCT dti-1406 23 18 by by ADP dti-1406 23 19 - - PUNCT dti-1406 23 20 nc nc PROPN dti-1406 23 21 3.0 3.0 NUM dti-1406 23 22 license license NOUN dti-1406 23 23 . . PUNCT dti-1406 24 1 correspondence correspondence NOUN dti-1406 24 2 : : PUNCT dti-1406 24 3 oguzmutlu80@hotmail.com oguzmutlu80@hotmail.com X dti-1406 24 4 paper paper NOUN dti-1406 24 5 subject subject NOUN dti-1406 24 6 to to ADP dti-1406 24 7 independent independent ADJ dti-1406 24 8 expert expert NOUN dti-1406 24 9 blind blind ADJ dti-1406 24 10 peer peer NOUN dti-1406 24 11 review review NOUN dti-1406 24 12 by by ADP dti-1406 24 13 minimum minimum NOUN dti-1406 24 14 of of ADP dti-1406 24 15 two two NUM dti-1406 24 16 reviewers reviewer NOUN dti-1406 24 17 . . PUNCT dti-1406 25 1 all all DET dti-1406 25 2 editorial editorial ADJ dti-1406 25 3 decisions decision NOUN dti-1406 25 4 made make VERB dti-1406 25 5 by by ADP dti-1406 25 6 independent independent ADJ dti-1406 25 7 academic academic ADJ dti-1406 25 8 editor editor NOUN dti-1406 25 9 . . PUNCT dti-1406 26 1 upon upon SCONJ dti-1406 26 2 submission submission NOUN dti-1406 26 3 manuscript manuscript NOUN dti-1406 26 4 was be AUX dti-1406 26 5 subject subject ADJ dti-1406 26 6 to to ADP dti-1406 26 7 anti anti ADJ dti-1406 26 8 - - NOUN dti-1406 26 9 plagiarism plagiarism ADJ dti-1406 26 10 scanning scanning NOUN dti-1406 26 11 . . PUNCT dti-1406 27 1 prior prior ADV dti-1406 27 2 to to ADP dti-1406 27 3 publication publication NOUN dti-1406 27 4 all all DET dti-1406 27 5 authors author NOUN dti-1406 27 6 have have AUX dti-1406 27 7 given give VERB dti-1406 27 8 signed sign VERB dti-1406 27 9 confirmation confirmation NOUN dti-1406 27 10 of of ADP dti-1406 27 11 agreement agreement NOUN dti-1406 27 12 to to ADP dti-1406 27 13 article article NOUN dti-1406 27 14 publication publication NOUN dti-1406 27 15 and and CCONJ dti-1406 27 16 compliance compliance NOUN dti-1406 27 17 with with ADP dti-1406 27 18 all all DET dti-1406 27 19 applicable applicable ADJ dti-1406 27 20 ethical ethical ADJ dti-1406 27 21 and and CCONJ dti-1406 27 22 legal legal ADJ dti-1406 27 23 requirements requirement NOUN dti-1406 27 24 , , PUNCT dti-1406 27 25 including include VERB dti-1406 27 26 the the DET dti-1406 27 27 accuracy accuracy NOUN dti-1406 27 28 of of ADP dti-1406 27 29 author author NOUN dti-1406 27 30 and and CCONJ dti-1406 27 31 contributor contributor NOUN dti-1406 27 32 information information NOUN dti-1406 27 33 , , PUNCT dti-1406 27 34 disclosure disclosure NOUN dti-1406 27 35 of of ADP dti-1406 27 36 competing compete VERB dti-1406 27 37 interests interest NOUN dti-1406 27 38 and and CCONJ dti-1406 27 39 funding funding NOUN dti-1406 27 40 sources source NOUN dti-1406 27 41 , , PUNCT dti-1406 27 42 compliance compliance NOUN dti-1406 27 43 with with ADP dti-1406 27 44 ethical ethical ADJ dti-1406 27 45 requirements requirement NOUN dti-1406 27 46 relating relate VERB dti-1406 27 47 to to ADP dti-1406 27 48 human human ADJ dti-1406 27 49 and and CCONJ dti-1406 27 50 animal animal NOUN dti-1406 27 51 study study NOUN dti-1406 27 52 participants participant NOUN dti-1406 27 53 , , PUNCT dti-1406 27 54 and and CCONJ dti-1406 27 55 compliance compliance NOUN dti-1406 27 56 with with ADP dti-1406 27 57 any any DET dti-1406 27 58 copyright copyright NOUN dti-1406 27 59 requirements requirement NOUN dti-1406 27 60 of of ADP dti-1406 27 61 third third ADJ dti-1406 27 62 parties party NOUN dti-1406 27 63 . . PUNCT dti-1406 28 1 this this DET dti-1406 28 2 journal journal NOUN dti-1406 28 3 is be AUX dti-1406 28 4 a a DET dti-1406 28 5 member member NOUN dti-1406 28 6 of of ADP dti-1406 28 7 the the DET dti-1406 28 8 committee committee NOUN dti-1406 28 9 on on ADP dti-1406 28 10 publication publication NOUN dti-1406 28 11 ethics ethic NOUN dti-1406 28 12 ( ( PUNCT dti-1406 28 13 cope cope PROPN dti-1406 28 14 ) ) PUNCT dti-1406 28 15 . . PUNCT dti-1406 29 1 published publish VERB dti-1406 29 2 by by ADP dti-1406 29 3 libertas liberta NOUN dti-1406 29 4 academica academica PROPN dti-1406 29 5 . . PUNCT dti-1406 30 1 learn learn VERB dti-1406 30 2 more more ADJ dti-1406 30 3 about about ADP dti-1406 30 4 this this DET dti-1406 30 5 journal journal NOUN dti-1406 30 6 . . PUNCT dti-1406 31 1 introduction introduction NOUN dti-1406 31 2 nitric nitric ADJ dti-1406 31 3 oxide oxide NOUN dti-1406 31 4 ( ( PUNCT dti-1406 31 5 no no NOUN dti-1406 31 6 ) ) PUNCT dti-1406 31 7 is be AUX dti-1406 31 8 synthesized synthesize VERB dti-1406 31 9 from from ADP dti-1406 31 10 l l NOUN dti-1406 31 11 - - NOUN dti-1406 31 12 arginine arginine NOUN dti-1406 31 13 by by ADP dti-1406 31 14 no no DET dti-1406 31 15 synthase synthase NOUN dti-1406 31 16 ( ( PUNCT dti-1406 31 17 nos nos NOUN dti-1406 31 18 ) ) PUNCT dti-1406 31 19 as as ADP dti-1406 31 20 a a DET dti-1406 31 21 result result NOUN dti-1406 31 22 of of ADP dti-1406 31 23 ca2 ca2 PROPN dti-1406 31 24 + + PROPN dti-1406 31 25 influx influx NOUN dti-1406 31 26 , , PUNCT dti-1406 31 27 which which PRON dti-1406 31 28 is be AUX dti-1406 31 29 activated activate VERB dti-1406 31 30 by by ADP dti-1406 31 31 induction induction NOUN dti-1406 31 32 of of ADP dti-1406 31 33 n n CCONJ dti-1406 31 34 - - PUNCT dti-1406 31 35 methyl methyl NOUN dti-1406 31 36 - - PUNCT dti-1406 31 37 d d NOUN dti-1406 31 38 - - NOUN dti-1406 31 39 aspartate aspartate ADJ dti-1406 31 40 ( ( PUNCT dti-1406 31 41 nmda nmda ADJ dti-1406 31 42 ) ) PUNCT dti-1406 31 43 receptors receptor NOUN dti-1406 31 44 by by ADP dti-1406 31 45 excitatory excitatory ADJ dti-1406 31 46 amino amino NOUN dti-1406 31 47 acids acid NOUN dti-1406 31 48 . . PUNCT dti-1406 32 1 no no DET dti-1406 32 2 acts act NOUN dti-1406 32 3 as as ADP dti-1406 32 4 an an DET dti-1406 32 5 atypical atypical ADJ dti-1406 32 6 neuromediator neuromediator NOUN dti-1406 32 7 inside inside ADP dti-1406 32 8 brain brain NOUN dti-1406 32 9 cells cell NOUN dti-1406 32 10 because because SCONJ dti-1406 32 11 it it PRON dti-1406 32 12 reacts react VERB dti-1406 32 13 with with ADP dti-1406 32 14 heme heme ADJ dti-1406 32 15 moieties moiety NOUN dti-1406 32 16 of of ADP dti-1406 32 17 guanyl guanyl NOUN dti-1406 32 18 cyclase cyclase NOUN dti-1406 32 19 in in ADP dti-1406 32 20 the the DET dti-1406 32 21 synaptic synaptic ADJ dti-1406 32 22 junction junction NOUN dti-1406 32 23 and and CCONJ dti-1406 32 24 induces induce VERB dti-1406 32 25 cyclic cyclic PROPN dti-1406 32 26 guanosine guanosine NOUN dti-1406 32 27 monophosphate monophosphate NOUN dti-1406 32 28 ( ( PUNCT dti-1406 32 29 cgmp)-mediated cgmp)-mediate VERB dti-1406 32 30 presynaptic presynaptic ADJ dti-1406 32 31 glutamate glutamate NOUN dti-1406 32 32 release release NOUN dti-1406 32 33 . . PUNCT dti-1406 33 1 no no PRON dti-1406 33 2 is be AUX dti-1406 33 3 produced produce VERB dti-1406 33 4 both both CCONJ dti-1406 33 5 presynaptically presynaptically ADV dti-1406 33 6 and and CCONJ dti-1406 33 7 postsynaptically postsynaptically ADV dti-1406 33 8 in in ADP dti-1406 33 9 the the DET dti-1406 33 10 brain brain NOUN dti-1406 33 11 as as ADP dti-1406 33 12 a a DET dti-1406 33 13 result result NOUN dti-1406 33 14 of of ADP dti-1406 33 15 the the DET dti-1406 33 16 increase increase NOUN dti-1406 33 17 in in ADP dti-1406 33 18 cytosolic cytosolic ADJ dti-1406 33 19 ca2 ca2 PROPN dti-1406 33 20 + + PROPN dti-1406 33 21 concentration concentration NOUN dti-1406 33 22 ; ; PUNCT dti-1406 33 23 it it PRON dti-1406 33 24 subsequently subsequently ADV dti-1406 33 25 diffuses diffuse VERB dti-1406 33 26 outside outside ADV dti-1406 33 27 and and CCONJ dti-1406 33 28 affects affect VERB dti-1406 33 29 the the DET dti-1406 33 30 neighboring neighbor VERB dti-1406 33 31 neuronal neuronal ADJ dti-1406 33 32 structures structure NOUN dti-1406 33 33 and and CCONJ dti-1406 33 34 glial glial ADJ dti-1406 33 35 cells.1 cells.1 PROPN dti-1406 33 36 no no PRON dti-1406 33 37 has have VERB dti-1406 33 38 several several ADJ dti-1406 33 39 effects effect NOUN dti-1406 33 40 on on ADP dti-1406 33 41 behavior behavior NOUN dti-1406 33 42 , , PUNCT dti-1406 33 43 cognition cognition NOUN dti-1406 33 44 , , PUNCT dti-1406 33 45 and and CCONJ dti-1406 33 46 emotion emotion NOUN dti-1406 33 47 , , PUNCT dti-1406 33 48 and and CCONJ dti-1406 33 49 has have AUX dti-1406 33 50 been be AUX dti-1406 33 51 shown show VERB dti-1406 33 52 to to PART dti-1406 33 53 play play VERB dti-1406 33 54 role role NOUN dti-1406 33 55 in in ADP dti-1406 33 56 depression depression NOUN dti-1406 33 57 , , PUNCT dti-1406 33 58 anxiety anxiety NOUN dti-1406 33 59 , , PUNCT dti-1406 33 60 locomotion locomotion NOUN dti-1406 33 61 , , PUNCT dti-1406 33 62 aggression aggression NOUN dti-1406 33 63 , , PUNCT dti-1406 33 64 tolerance tolerance NOUN dti-1406 33 65 , , PUNCT dti-1406 33 66 addiction addiction NOUN dti-1406 33 67 , , PUNCT dti-1406 33 68 and and CCONJ dti-1406 33 69 learning.2–4 learning.2–4 NOUN dti-1406 34 1 no no PRON dti-1406 34 2 has have VERB dti-1406 34 3 effects effect NOUN dti-1406 34 4 on on ADP dti-1406 34 5 the the DET dti-1406 34 6 modulation modulation NOUN dti-1406 34 7 of of ADP dti-1406 34 8 cognition;5 cognition;5 PROPN dti-1406 34 9 however however ADV dti-1406 34 10 , , PUNCT dti-1406 34 11 role role NOUN dti-1406 34 12 of of ADP dti-1406 34 13 no no PRON dti-1406 34 14 in in ADP dti-1406 34 15 learning learning NOUN dti-1406 34 16 is be AUX dti-1406 34 17 not not PART dti-1406 34 18 completely completely ADV dti-1406 34 19 understood understand VERB dti-1406 34 20 . . PUNCT dti-1406 35 1 multiple multiple ADJ dti-1406 35 2 mechanisms mechanism NOUN dti-1406 35 3 modulate modulate VERB dti-1406 35 4 synaptic synaptic ADJ dti-1406 35 5 efficacy efficacy NOUN dti-1406 35 6 and and CCONJ dti-1406 35 7 its its PRON dti-1406 35 8 actions action NOUN dti-1406 35 9 , , PUNCT dti-1406 35 10 including include VERB dti-1406 35 11 the the DET dti-1406 35 12 regulation regulation NOUN dti-1406 35 13 of of ADP dti-1406 35 14 synaptic synaptic ADJ dti-1406 35 15 plasticity plasticity NOUN dti-1406 35 16 and and CCONJ dti-1406 35 17 the the DET dti-1406 35 18 modulation modulation NOUN dti-1406 35 19 of of ADP dti-1406 35 20 cgmp.6 cgmp.6 PROPN dti-1406 35 21 there there PRON dti-1406 35 22 is be VERB dti-1406 35 23 evidence evidence NOUN dti-1406 35 24 of of ADP dti-1406 35 25 soluble soluble ADJ dti-1406 35 26 guanylyl guanylyl ADJ dti-1406 35 27 cyclase cyclase NOUN dti-1406 35 28 ( ( PUNCT dti-1406 35 29 sgc sgc NOUN dti-1406 35 30 ) ) PUNCT dti-1406 35 31 activation activation NOUN dti-1406 35 32 in in ADP dti-1406 35 33 memory memory NOUN dti-1406 35 34 formation.7–9 formation.7–9 ADP dti-1406 35 35 the the DET dti-1406 35 36 activation activation NOUN dti-1406 35 37 of of ADP dti-1406 35 38 sgc sgc PROPN dti-1406 35 39 may may AUX dti-1406 35 40 represent represent VERB dti-1406 35 41 a a DET dti-1406 35 42 major major ADJ dti-1406 35 43 pathway pathway NOUN dti-1406 35 44 that that PRON dti-1406 35 45 regulates regulate VERB dti-1406 35 46 no no DET dti-1406 35 47 messenger messenger NOUN dti-1406 35 48 function function NOUN dti-1406 35 49 in in ADP dti-1406 35 50 the the DET dti-1406 35 51 brain10,11 brain10,11 NOUN dti-1406 35 52 because because SCONJ dti-1406 35 53 it it PRON dti-1406 35 54 has have AUX dti-1406 35 55 been be AUX dti-1406 35 56 reported report VERB dti-1406 35 57 that that SCONJ dti-1406 35 58 the the DET dti-1406 35 59 induction induction NOUN dti-1406 35 60 of of ADP dti-1406 35 61 long long ADJ dti-1406 35 62 - - PUNCT dti-1406 35 63 term term NOUN dti-1406 35 64 potentiation potentiation NOUN dti-1406 35 65 ( ( PUNCT dti-1406 35 66 ltp ltp NOUN dti-1406 35 67 ) ) PUNCT dti-1406 35 68 in in ADP dti-1406 35 69 hippocampal hippocampal ADJ dti-1406 35 70 slices slice NOUN dti-1406 35 71 can can AUX dti-1406 35 72 be be AUX dti-1406 35 73 blocked block VERB dti-1406 35 74 with with ADP dti-1406 35 75 sgc sgc PROPN dti-1406 35 76 inhibitors.12,13 inhibitors.12,13 NOUN dti-1406 35 77 in in ADP dti-1406 35 78 different different ADJ dti-1406 35 79 rodent rodent NOUN dti-1406 35 80 models model NOUN dti-1406 35 81 , , PUNCT dti-1406 35 82 many many ADJ dti-1406 35 83 studies study NOUN dti-1406 35 84 have have AUX dti-1406 35 85 investigated investigate VERB dti-1406 35 86 drugs drug NOUN dti-1406 35 87 that that PRON dti-1406 35 88 affect affect VERB dti-1406 35 89 no no DET dti-1406 35 90 levels level NOUN dti-1406 35 91 to to PART dti-1406 35 92 examine examine VERB dti-1406 35 93 the the DET dti-1406 35 94 role role NOUN dti-1406 35 95 on on ADP dti-1406 35 96 cognition cognition NOUN dti-1406 35 97 ; ; PUNCT dti-1406 35 98 however however ADV dti-1406 35 99 , , PUNCT dti-1406 35 100 the the DET dti-1406 35 101 results result NOUN dti-1406 35 102 have have AUX dti-1406 35 103 been be AUX dti-1406 35 104 controversial controversial ADJ dti-1406 35 105 . . PUNCT dti-1406 36 1 in in ADP dti-1406 36 2 some some DET dti-1406 36 3 studies study NOUN dti-1406 36 4 , , PUNCT dti-1406 36 5 it it PRON dti-1406 36 6 was be AUX dti-1406 36 7 shown show VERB dti-1406 36 8 that that SCONJ dti-1406 36 9 compounds compound VERB dti-1406 36 10 that that PRON dti-1406 36 11 block block NOUN dti-1406 36 12 nos nos X dti-1406 36 13 inhibited inhibit VERB dti-1406 36 14 learning,14,15 learning,14,15 PROPN dti-1406 36 15 whereas whereas SCONJ dti-1406 36 16 some some DET dti-1406 36 17 others other NOUN dti-1406 36 18 did do AUX dti-1406 36 19 not not PART dti-1406 36 20 support support VERB dti-1406 36 21 these these DET dti-1406 36 22 findings.16,17 findings.16,17 NOUN dti-1406 36 23 in in ADP dti-1406 36 24 the the DET dti-1406 36 25 morris morris PROPN dti-1406 36 26 water water PROPN dti-1406 36 27 maze maze NOUN dti-1406 36 28 ( ( PUNCT dti-1406 36 29 mwm mwm NOUN dti-1406 36 30 ) ) PUNCT dti-1406 36 31 test test NOUN dti-1406 36 32 , , PUNCT dti-1406 36 33 systemic systemic ADJ dti-1406 36 34 inhibition inhibition NOUN dti-1406 36 35 of of ADP dti-1406 36 36 no no PRON dti-1406 36 37 had have VERB dti-1406 36 38 disturbing disturbing ADJ dti-1406 36 39 effects effect NOUN dti-1406 36 40 in in ADP dti-1406 36 41 some some DET dti-1406 36 42 studies,18,19 studies,18,19 PROPN dti-1406 36 43 whereas whereas SCONJ dti-1406 36 44 others other NOUN dti-1406 36 45 showed show VERB dti-1406 36 46 different different ADJ dti-1406 36 47 results.17,20 results.17,20 NOUN dti-1406 36 48 besides besides SCONJ dti-1406 36 49 , , PUNCT dti-1406 36 50 ltp ltp PROPN dti-1406 36 51 playing play VERB dti-1406 36 52 a a DET dti-1406 36 53 role role NOUN dti-1406 36 54 in in ADP dti-1406 36 55 no no PRON dti-1406 36 56 - - PUNCT dti-1406 36 57 mediated mediate VERB dti-1406 36 58 cognition cognition NOUN dti-1406 36 59 was be AUX dti-1406 36 60 completely completely ADV dti-1406 36 61 revered revere VERB dti-1406 36 62 after after ADP dti-1406 36 63 the the DET dti-1406 36 64 administration administration NOUN dti-1406 36 65 of of ADP dti-1406 36 66 nos nos PROPN dti-1406 36 67 inhibitors inhibitor NOUN dti-1406 36 68 in in ADP dti-1406 36 69 some some DET dti-1406 36 70 studies,21,22 studies,21,22 NOUN dti-1406 36 71 whereas whereas SCONJ dti-1406 36 72 others other NOUN dti-1406 36 73 studies study NOUN dti-1406 36 74 have have AUX dti-1406 36 75 demonstrated demonstrate VERB dti-1406 36 76 a a DET dti-1406 36 77 partial partial ADJ dti-1406 36 78 inhibition13,23 inhibition13,23 NOUN dti-1406 36 79 or or CCONJ dti-1406 36 80 no no DET dti-1406 36 81 effect effect NOUN dti-1406 36 82 at at ADP dti-1406 36 83 all.24,25 all.24,25 PROPN dti-1406 36 84 several several ADJ dti-1406 36 85 studies study NOUN dti-1406 36 86 regarding regard VERB dti-1406 36 87 nos nos PROPN dti-1406 36 88 inhibitors inhibitor NOUN dti-1406 36 89 demonstrated demonstrate VERB dti-1406 36 90 that that SCONJ dti-1406 36 91 7 7 NUM dti-1406 36 92 - - PUNCT dti-1406 36 93 nitroindazole nitroindazole NOUN dti-1406 36 94 ( ( PUNCT dti-1406 36 95 7 7 NUM dti-1406 36 96 - - PUNCT dti-1406 36 97 ni ni NOUN dti-1406 36 98 ) ) PUNCT dti-1406 36 99 exerted exert VERB dti-1406 36 100 some some DET dti-1406 36 101 impairing impair VERB dti-1406 36 102 effects effect NOUN dti-1406 36 103 on on ADP dti-1406 36 104 cognition cognition NOUN dti-1406 36 105 in in ADP dti-1406 36 106 rodents rodent NOUN dti-1406 36 107 . . PUNCT dti-1406 37 1 injections injection NOUN dti-1406 37 2 of of ADP dti-1406 37 3 7 7 NUM dti-1406 37 4 - - PUNCT dti-1406 37 5 ni ni NOUN dti-1406 37 6 disturbed disturb VERB dti-1406 37 7 spatial spatial ADJ dti-1406 37 8 memory memory NOUN dti-1406 37 9 and and CCONJ dti-1406 37 10 object object NOUN dti-1406 37 11 recognition recognition NOUN dti-1406 37 12 in in ADP dti-1406 37 13 rats rat NOUN dti-1406 37 14 and and CCONJ dti-1406 37 15 also also ADV dti-1406 37 16 had have AUX dti-1406 37 17 impairing impair VERB dti-1406 37 18 effects effect NOUN dti-1406 37 19 in in ADP dti-1406 37 20 passive passive ADJ dti-1406 37 21 avoidance avoidance NOUN dti-1406 37 22 test test NOUN dti-1406 37 23 in in ADP dti-1406 37 24 animal animal NOUN dti-1406 37 25 models.26–28 models.26–28 PROPN dti-1406 37 26 journal journal PROPN dti-1406 37 27 name name NOUN dti-1406 37 28 : : PUNCT dti-1406 37 29 drug drug NOUN dti-1406 37 30 target target NOUN dti-1406 37 31 insights insight NOUN dti-1406 37 32 journal journal NOUN dti-1406 37 33 type type NOUN dti-1406 37 34 : : PUNCT dti-1406 37 35 original original ADJ dti-1406 37 36 research research NOUN dti-1406 37 37 year year NOUN dti-1406 37 38 : : PUNCT dti-1406 37 39 2015 2015 NUM dti-1406 37 40 volume volume NOUN dti-1406 37 41 : : PUNCT dti-1406 37 42 9 9 NUM dti-1406 37 43 running run VERB dti-1406 37 44 head head NOUN dti-1406 37 45 verso verso NOUN dti-1406 37 46 : : PUNCT dti-1406 38 1 mutlu mutlu PROPN dti-1406 38 2 et et PROPN dti-1406 38 3 al al PROPN dti-1406 38 4 running run VERB dti-1406 38 5 head head NOUN dti-1406 38 6 recto recto ADJ dti-1406 38 7 : : PUNCT dti-1406 38 8 7 7 NUM dti-1406 38 9 - - PUNCT dti-1406 38 10 ni ni NOUN dti-1406 38 11 and and CCONJ dti-1406 38 12 odq odq NOUN dti-1406 38 13 disturbs disturb VERB dti-1406 38 14 memory memory NOUN dti-1406 38 15 in in ADP dti-1406 38 16 the the DET dti-1406 38 17 elevated elevated ADJ dti-1406 38 18 plus plus CCONJ dti-1406 38 19 maze maze NOUN dti-1406 38 20 http://www.la-press.com/drug-target-insights-journal-j23 http://www.la-press.com/drug-target-insights-journal-j23 PROPN dti-1406 38 21 http://www.la-press.com http://www.la-press.com X dti-1406 39 1 http://dx.doi.org/10.4137/dti.s23378 http://dx.doi.org/10.4137/dti.s23378 PRON dti-1406 39 2 http://creativecommons.org/licenses/by-nc/3.0/ http://creativecommons.org/licenses/by-nc/3.0/ PROPN dti-1406 39 3 http://creativecommons.org/licenses/by-nc/3.0/ http://creativecommons.org/licenses/by-nc/3.0/ NOUN dti-1406 39 4 mailto:oguzmutlu80@hotmail.com mailto:oguzmutlu80@hotmail.com PROPN dti-1406 39 5 http://www.la-press.com http://www.la-press.com X dti-1406 39 6 http://www.la-press.com/drug-target-insights-journal-j23 http://www.la-press.com/drug-target-insights-journal-j23 PROPN dti-1406 39 7 mutlu mutlu PROPN dti-1406 39 8 et et PROPN dti-1406 39 9 al al PROPN dti-1406 39 10 2 2 NUM dti-1406 39 11 drug drug NOUN dti-1406 39 12 target target NOUN dti-1406 39 13 insights insight NOUN dti-1406 39 14 2015:9 2015:9 NUM dti-1406 39 15 the the DET dti-1406 39 16 goal goal NOUN dti-1406 39 17 of of ADP dti-1406 39 18 this this DET dti-1406 39 19 study study NOUN dti-1406 39 20 was be AUX dti-1406 39 21 to to PART dti-1406 39 22 further far ADV dti-1406 39 23 evaluate evaluate VERB dti-1406 39 24 the the DET dti-1406 39 25 effects effect NOUN dti-1406 39 26 of of ADP dti-1406 39 27 7 7 NUM dti-1406 39 28 - - PUNCT dti-1406 39 29 ni ni NOUN dti-1406 39 30 ( ( PUNCT dti-1406 39 31 a a DET dti-1406 39 32 nonselective nonselective ADJ dti-1406 39 33 inhibitor inhibitor NOUN dti-1406 39 34 of of ADP dti-1406 39 35 nos no NOUN dti-1406 39 36 ) ) PUNCT dti-1406 39 37 , , PUNCT dti-1406 40 1 l l NOUN dti-1406 40 2 - - NOUN dti-1406 40 3 arginine arginine NOUN dti-1406 40 4 ( ( PUNCT dti-1406 40 5 an an DET dti-1406 40 6 no no DET dti-1406 40 7 precursor precursor NOUN dti-1406 40 8 combined combine VERB dti-1406 40 9 with with ADP dti-1406 40 10 7 7 NUM dti-1406 40 11 - - PUNCT dti-1406 40 12 ni ni NOUN dti-1406 40 13 ) ) PUNCT dti-1406 40 14 , , PUNCT dti-1406 40 15 and and CCONJ dti-1406 40 16 1h-[1,2,4]oxadiazole[4,3a]-quinoxaline-1 1h-[1,2,4]oxadiazole[4,3a]-quinoxaline-1 NUM dti-1406 40 17 - - SYM dti-1406 40 18 one one NUM dti-1406 40 19 ( ( PUNCT dti-1406 40 20 odq odq NOUN dti-1406 40 21 , , PUNCT dti-1406 40 22 a a DET dti-1406 40 23 highly highly ADV dti-1406 40 24 selective selective ADJ dti-1406 40 25 , , PUNCT dti-1406 40 26 irreversible irreversible ADJ dti-1406 40 27 inhibitor inhibitor NOUN dti-1406 40 28 of of ADP dti-1406 40 29 sgc sgc PROPN dti-1406 40 30 ) ) PUNCT dti-1406 40 31 on on ADP dti-1406 40 32 spatial spatial ADJ dti-1406 40 33 memory memory NOUN dti-1406 40 34 in in ADP dti-1406 40 35 the the DET dti-1406 40 36 modified modify VERB dti-1406 40 37 elevated elevated ADJ dti-1406 40 38 plus plus CCONJ dti-1406 40 39 maze maze NOUN dti-1406 40 40 ( ( PUNCT dti-1406 40 41 mepm mepm NOUN dti-1406 40 42 ) ) PUNCT dti-1406 40 43 , , PUNCT dti-1406 40 44 mwm mwm NOUN dti-1406 40 45 , , PUNCT dti-1406 40 46 and and CCONJ dti-1406 40 47 radial radial ADJ dti-1406 40 48 arm arm NOUN dti-1406 40 49 maze maze NOUN dti-1406 40 50 ( ( PUNCT dti-1406 40 51 ram ram NOUN dti-1406 40 52 ) ) PUNCT dti-1406 40 53 tests test NOUN dti-1406 40 54 . . PUNCT dti-1406 41 1 furthermore furthermore ADV dti-1406 41 2 , , PUNCT dti-1406 41 3 these these DET dti-1406 41 4 studies study NOUN dti-1406 41 5 were be AUX dti-1406 41 6 aimed aim VERB dti-1406 41 7 at at ADP dti-1406 41 8 further far ADV dti-1406 41 9 understanding understand VERB dti-1406 41 10 the the DET dti-1406 41 11 effects effect NOUN dti-1406 41 12 of of ADP dti-1406 41 13 no no PRON dti-1406 41 14 on on ADP dti-1406 41 15 cognition cognition NOUN dti-1406 41 16 because because SCONJ dti-1406 41 17 of of ADP dti-1406 41 18 the the DET dti-1406 41 19 controversy controversy NOUN dti-1406 41 20 in in ADP dti-1406 41 21 the the DET dti-1406 41 22 literature literature NOUN dti-1406 41 23 . . PUNCT dti-1406 42 1 methods method NOUN dti-1406 42 2 animals animal NOUN dti-1406 42 3 . . PUNCT dti-1406 43 1 ninety ninety NUM dti-1406 43 2 - - PUNCT dti-1406 43 3 six six NUM dti-1406 43 4 male male ADJ dti-1406 43 5 inbred inbreed VERB dti-1406 43 6 balb balb NOUN dti-1406 43 7 / / SYM dti-1406 43 8 c c NOUN dti-1406 43 9 byj byj PROPN dti-1406 43 10 mice mouse NOUN dti-1406 43 11 ( ( PUNCT dti-1406 43 12 uludağ uludağ NOUN dti-1406 43 13 university university NOUN dti-1406 43 14 , , PUNCT dti-1406 43 15 bursa bursa NOUN dti-1406 43 16 , , PUNCT dti-1406 43 17 turkey turkey PROPN dti-1406 43 18 ) ) PUNCT dti-1406 43 19 aged aged ADJ dti-1406 43 20 8 8 NUM dti-1406 43 21     SPACE dti-1406 43 22 weeks week NOUN dti-1406 43 23 were be AUX dti-1406 43 24 used use VERB dti-1406 43 25 in in ADP dti-1406 43 26 this this DET dti-1406 43 27 study study NOUN dti-1406 43 28 . . PUNCT dti-1406 44 1 the the DET dti-1406 44 2 animals animal NOUN dti-1406 44 3 ( ( PUNCT dti-1406 44 4 4–5 4–5 NUM dti-1406 44 5 per per ADP dti-1406 44 6 cage cage NOUN dti-1406 44 7 ) ) PUNCT dti-1406 44 8 were be AUX dti-1406 44 9 kept keep VERB dti-1406 44 10 in in ADP dti-1406 44 11 the the DET dti-1406 44 12 laboratory laboratory NOUN dti-1406 44 13 for for ADP dti-1406 44 14 2 2 NUM dti-1406 44 15     SPACE dti-1406 44 16 weeks week NOUN dti-1406 44 17 prior prior ADV dti-1406 44 18 to to ADP dti-1406 44 19 experimentation experimentation NOUN dti-1406 44 20 . . PUNCT dti-1406 45 1 the the DET dti-1406 45 2 animal animal NOUN dti-1406 45 3 room room NOUN dti-1406 45 4 had have VERB dti-1406 45 5 a a DET dti-1406 45 6 temperature temperature NOUN dti-1406 45 7 of of ADP dti-1406 45 8 21 21 NUM dti-1406 45 9     SPACE dti-1406 45 10 ± ± NOUN dti-1406 45 11     SPACE dti-1406 45 12 1.5 1.5 NUM dti-1406 45 13 ° ° ADP dti-1406 45 14 c c NOUN dti-1406 45 15 with with ADP dti-1406 45 16 60 60 NUM dti-1406 45 17 % % NOUN dti-1406 45 18 relative relative ADJ dti-1406 45 19 humidity humidity NOUN dti-1406 45 20 , , PUNCT dti-1406 45 21 and and CCONJ dti-1406 45 22 a a DET dti-1406 45 23 12 12 NUM dti-1406 45 24 - - PUNCT dti-1406 45 25 hour hour NOUN dti-1406 45 26 light light ADJ dti-1406 45 27 / / SYM dti-1406 45 28 dark dark ADJ dti-1406 45 29 cycle cycle NOUN dti-1406 45 30 ( ( PUNCT dti-1406 45 31 light light NOUN dti-1406 45 32 on on ADV dti-1406 45 33 at at ADP dti-1406 45 34 8.00 8.00 NUM dti-1406 45 35 p.m. p.m. NOUN dti-1406 45 36 ) ) PUNCT dti-1406 45 37 . . PUNCT dti-1406 46 1 all all DET dti-1406 46 2 procedures procedure NOUN dti-1406 46 3 that that PRON dti-1406 46 4 involved involved ADJ dti-1406 46 5 animals animal NOUN dti-1406 46 6 were be AUX dti-1406 46 7 in in ADP dti-1406 46 8 compliance compliance NOUN dti-1406 46 9 with with ADP dti-1406 46 10 the the DET dti-1406 46 11 european european PROPN dti-1406 46 12 community community PROPN dti-1406 46 13 council council NOUN dti-1406 46 14 directive directive NOUN dti-1406 46 15 of of ADP dti-1406 46 16 november november PROPN dti-1406 46 17 24 24 NUM dti-1406 46 18 , , PUNCT dti-1406 46 19 1986 1986 NUM dti-1406 46 20 , , PUNCT dti-1406 46 21 and and CCONJ dti-1406 46 22 ethical ethical ADJ dti-1406 46 23 approval approval NOUN dti-1406 46 24 was be AUX dti-1406 46 25 granted grant VERB dti-1406 46 26 by by ADP dti-1406 46 27 the the DET dti-1406 46 28 kocaeli kocaeli PROPN dti-1406 46 29 university university PROPN dti-1406 46 30 ethics ethic NOUN dti-1406 46 31 committee committee PROPN dti-1406 46 32 ( ( PUNCT dti-1406 46 33 number number NOUN dti-1406 46 34 : : PUNCT dti-1406 46 35 aek aek PROPN dti-1406 46 36 9/4 9/4 NUM dti-1406 46 37 - - SYM dti-1406 46 38 2010 2010 NUM dti-1406 46 39 , , PUNCT dti-1406 46 40 kocaeli kocaeli ADJ dti-1406 46 41 , , PUNCT dti-1406 46 42 turkey turkey PROPN dti-1406 46 43 ) ) PUNCT dti-1406 46 44 . . PUNCT dti-1406 47 1 modified modify VERB dti-1406 47 2 elevated elevated ADJ dti-1406 47 3 plus plus CCONJ dti-1406 47 4 - - PUNCT dti-1406 47 5 maze maze NOUN dti-1406 47 6 test test NOUN dti-1406 47 7 . . PUNCT dti-1406 48 1 cognitive cognitive ADJ dti-1406 48 2 behavior behavior NOUN dti-1406 48 3 was be AUX dti-1406 48 4 determined determine VERB dti-1406 48 5 using use VERB dti-1406 48 6 the the DET dti-1406 48 7 mepm mepm NOUN dti-1406 48 8 , , PUNCT dti-1406 48 9 which which PRON dti-1406 48 10 measures measure VERB dti-1406 48 11 spatial spatial ADJ dti-1406 48 12 long long ADJ dti-1406 48 13 - - PUNCT dti-1406 48 14 term term NOUN dti-1406 48 15 memory.29 memory.29 NOUN dti-1406 48 16 the the DET dti-1406 48 17 maze maze NOUN dti-1406 48 18 was be AUX dti-1406 48 19 composed compose VERB dti-1406 48 20 of of ADP dti-1406 48 21 wood wood NOUN dti-1406 48 22 ; ; PUNCT dti-1406 48 23 it it PRON dti-1406 48 24 comprised comprise VERB dti-1406 48 25 two two NUM dti-1406 48 26 open open ADJ dti-1406 48 27 arms arm NOUN dti-1406 48 28 ( ( PUNCT dti-1406 48 29 29 29 NUM dti-1406 48 30     SPACE dti-1406 48 31 × × NOUN dti-1406 48 32     SPACE dti-1406 48 33 5 5 NUM dti-1406 48 34     SPACE dti-1406 48 35 cm cm NOUN dti-1406 48 36 ) ) PUNCT dti-1406 48 37 surrounded surround VERB dti-1406 48 38 by by ADP dti-1406 48 39 a a DET dti-1406 48 40 short short ADJ dti-1406 48 41 ( ( PUNCT dti-1406 48 42 1 1 NUM dti-1406 48 43     SPACE dti-1406 48 44 cm cm NOUN dti-1406 48 45 ) ) PUNCT dti-1406 48 46 plexiglass plexiglass NOUN dti-1406 48 47 edge edge NOUN dti-1406 48 48 to to PART dti-1406 48 49 avoid avoid VERB dti-1406 48 50 falls fall NOUN dti-1406 48 51 and and CCONJ dti-1406 48 52 two two NUM dti-1406 48 53 enclosed enclose VERB dti-1406 48 54 arms arm NOUN dti-1406 48 55 ( ( PUNCT dti-1406 48 56 29 29 NUM dti-1406 48 57     SPACE dti-1406 48 58 × × NOUN dti-1406 48 59     SPACE dti-1406 48 60 5 5 NUM dti-1406 48 61     SPACE dti-1406 48 62 × × NOUN dti-1406 48 63 15 15 NUM dti-1406 48 64     SPACE dti-1406 48 65 cm cm NOUN dti-1406 48 66 ) ) PUNCT dti-1406 48 67 arranged arrange VERB dti-1406 48 68 such such ADJ dti-1406 48 69 that that SCONJ dti-1406 48 70 the the DET dti-1406 48 71 two two NUM dti-1406 48 72 open open ADJ dti-1406 48 73 arms arm NOUN dti-1406 48 74 were be AUX dti-1406 48 75 opposite opposite ADJ dti-1406 48 76 to to ADP dti-1406 48 77 each each DET dti-1406 48 78 other other ADJ dti-1406 48 79 . . PUNCT dti-1406 49 1 the the DET dti-1406 49 2 arms arm NOUN dti-1406 49 3 were be AUX dti-1406 49 4 connected connect VERB dti-1406 49 5 by by ADP dti-1406 49 6 a a DET dti-1406 49 7 central central ADJ dti-1406 49 8 platform platform NOUN dti-1406 49 9 ( ( PUNCT dti-1406 49 10 5 5 NUM dti-1406 49 11     SPACE dti-1406 49 12 × × NOUN dti-1406 49 13     SPACE dti-1406 49 14 5 5 NUM dti-1406 49 15     SPACE dti-1406 49 16 cm cm NOUN dti-1406 49 17 ) ) PUNCT dti-1406 49 18 . . PUNCT dti-1406 50 1 the the DET dti-1406 50 2 maze maze NOUN dti-1406 50 3 was be AUX dti-1406 50 4 kept keep VERB dti-1406 50 5 40 40 NUM dti-1406 50 6     SPACE dti-1406 50 7 cm cm NOUN dti-1406 50 8 above above ADP dti-1406 50 9 the the DET dti-1406 50 10 floor floor NOUN dti-1406 50 11 . . PUNCT dti-1406 51 1 the the DET dti-1406 51 2 principle principle NOUN dti-1406 51 3 of of ADP dti-1406 51 4 this this DET dti-1406 51 5 experiment experiment NOUN dti-1406 51 6 is be AUX dti-1406 51 7 based base VERB dti-1406 51 8 on on ADP dti-1406 51 9 aversion aversion NOUN dti-1406 51 10 of of ADP dti-1406 51 11 rodents rodent NOUN dti-1406 51 12 to to PART dti-1406 51 13 open open VERB dti-1406 51 14 spaces space NOUN dti-1406 51 15 and and CCONJ dti-1406 51 16 heights height NOUN dti-1406 51 17 . . PUNCT dti-1406 52 1 the the DET dti-1406 52 2 animals animal NOUN dti-1406 52 3 prefer prefer VERB dti-1406 52 4 the the DET dti-1406 52 5 enclosed enclose VERB dti-1406 52 6 , , PUNCT dti-1406 52 7 protected protect VERB dti-1406 52 8 areas area NOUN dti-1406 52 9 of of ADP dti-1406 52 10 the the DET dti-1406 52 11 maze.29 maze.29 NOUN dti-1406 52 12 the the DET dti-1406 52 13 procedure procedure NOUN dti-1406 52 14 was be AUX dti-1406 52 15 as as ADV dti-1406 52 16 previously previously ADV dti-1406 52 17 described.29–32 described.29–32 NOUN dti-1406 52 18 in in ADP dti-1406 52 19 the the DET dti-1406 52 20 acquisition acquisition NOUN dti-1406 52 21 session session NOUN dti-1406 52 22 ( ( PUNCT dti-1406 52 23 day day NOUN dti-1406 52 24 1 1 NUM dti-1406 52 25 ) ) PUNCT dti-1406 52 26 , , PUNCT dti-1406 52 27 each each DET dti-1406 52 28 mouse mouse NOUN dti-1406 52 29 was be AUX dti-1406 52 30 placed place VERB dti-1406 52 31 at at ADP dti-1406 52 32 the the DET dti-1406 52 33 distal distal ADJ dti-1406 52 34 end end NOUN dti-1406 52 35 of of ADP dti-1406 52 36 an an DET dti-1406 52 37 open open ADJ dti-1406 52 38 arm arm NOUN dti-1406 52 39 facing face VERB dti-1406 52 40 away away ADV dti-1406 52 41 from from ADP dti-1406 52 42 central central ADJ dti-1406 52 43 platform platform NOUN dti-1406 52 44 . . PUNCT dti-1406 53 1 the the DET dti-1406 53 2 time time NOUN dti-1406 53 3 required require VERB dti-1406 53 4 for for ADP dti-1406 53 5 mice mouse NOUN dti-1406 53 6 to to PART dti-1406 53 7 move move VERB dti-1406 53 8 from from ADP dti-1406 53 9 the the DET dti-1406 53 10 open open ADJ dti-1406 53 11 arm arm NOUN dti-1406 53 12 to to ADP dti-1406 53 13 either either PRON dti-1406 53 14 of of ADP dti-1406 53 15 the the DET dti-1406 53 16 enclosed enclose VERB dti-1406 53 17 arms arm NOUN dti-1406 53 18 ( ( PUNCT dti-1406 53 19 transfer transfer NOUN dti-1406 53 20 latency latency NOUN dti-1406 53 21 ) ) PUNCT dti-1406 53 22 was be AUX dti-1406 53 23 recorded record VERB dti-1406 53 24 . . PUNCT dti-1406 54 1 training training NOUN dti-1406 54 2 ( ( PUNCT dti-1406 54 3 repeated repeat VERB dti-1406 54 4 exposure exposure NOUN dti-1406 54 5 of of ADP dti-1406 54 6 the the DET dti-1406 54 7 animals animal NOUN dti-1406 54 8 to to ADP dti-1406 54 9 the the DET dti-1406 54 10 open open ADJ dti-1406 54 11 arms arm NOUN dti-1406 54 12 ) ) PUNCT dti-1406 54 13 shortened shorten VERB dti-1406 54 14 this this DET dti-1406 54 15 parameter parameter NOUN dti-1406 54 16 , , PUNCT dti-1406 54 17 most most ADV dti-1406 54 18 likely likely ADJ dti-1406 54 19 as as ADP dti-1406 54 20 a a DET dti-1406 54 21 result result NOUN dti-1406 54 22 of of ADP dti-1406 54 23 learning learn VERB dti-1406 54 24 acquisition acquisition NOUN dti-1406 54 25 and and CCONJ dti-1406 54 26 retention retention NOUN dti-1406 54 27 . . PUNCT dti-1406 55 1 after after ADP dti-1406 55 2 entering enter VERB dti-1406 55 3 the the DET dti-1406 55 4 enclosed enclose VERB dti-1406 55 5 arm arm NOUN dti-1406 55 6 , , PUNCT dti-1406 55 7 the the DET dti-1406 55 8 mice mouse NOUN dti-1406 55 9 were be AUX dti-1406 55 10 allowed allow VERB dti-1406 55 11 to to PART dti-1406 55 12 move move VERB dti-1406 55 13 freely freely ADV dti-1406 55 14 in in ADP dti-1406 55 15 the the DET dti-1406 55 16 maze maze NOUN dti-1406 55 17 regardless regardless ADV dti-1406 55 18 of of ADP dti-1406 55 19 open open ADJ dti-1406 55 20 and and CCONJ dti-1406 55 21 enclosed enclose VERB dti-1406 55 22 arms arm NOUN dti-1406 55 23 for for ADP dti-1406 55 24 10 10 NUM dti-1406 55 25     SPACE dti-1406 55 26 seconds second NOUN dti-1406 55 27 . . PUNCT dti-1406 56 1 the the DET dti-1406 56 2 retention retention NOUN dti-1406 56 3 session session NOUN dti-1406 56 4 followed follow VERB dti-1406 56 5 24 24 NUM dti-1406 56 6     SPACE dti-1406 56 7 hours hour NOUN dti-1406 56 8 after after ADP dti-1406 56 9 the the DET dti-1406 56 10 acquisition acquisition NOUN dti-1406 56 11 session session NOUN dti-1406 56 12 . . PUNCT dti-1406 57 1 the the DET dti-1406 57 2 mice mouse NOUN dti-1406 57 3 were be AUX dti-1406 57 4 placed place VERB dti-1406 57 5 in in ADP dti-1406 57 6 the the DET dti-1406 57 7 open open ADJ dti-1406 57 8 arm arm NOUN dti-1406 57 9 , , PUNCT dti-1406 57 10 and and CCONJ dti-1406 57 11 the the DET dti-1406 57 12 transfer transfer NOUN dti-1406 57 13 latency latency NOUN dti-1406 57 14 was be AUX dti-1406 57 15 recorded record VERB dti-1406 57 16 again again ADV dti-1406 57 17 . . PUNCT dti-1406 58 1 the the DET dti-1406 58 2 experiments experiment NOUN dti-1406 58 3 were be AUX dti-1406 58 4 conducted conduct VERB dti-1406 58 5 between between ADP dti-1406 58 6 10:00 10:00 NUM dti-1406 58 7 and and CCONJ dti-1406 58 8 14:00 14:00 NUM dti-1406 58 9     SPACE dti-1406 58 10 hours hour NOUN dti-1406 58 11 in in ADP dti-1406 58 12 a a DET dti-1406 58 13 dimly dimly ADV dti-1406 58 14 lit light VERB dti-1406 58 15 , , PUNCT dti-1406 58 16 semi semi ADJ dti-1406 58 17 - - ADJ dti-1406 58 18 soundproof soundproof ADJ dti-1406 58 19 room room NOUN dti-1406 58 20 under under ADP dti-1406 58 21 natural natural ADJ dti-1406 58 22 light.29–32 light.29–32 NOUN dti-1406 58 23 morris morris PROPN dti-1406 58 24 water water PROPN dti-1406 58 25 maze maze NOUN dti-1406 58 26 test test NOUN dti-1406 58 27 . . PUNCT dti-1406 59 1 the the DET dti-1406 59 2 mwm mwm NOUN dti-1406 59 3 comprised comprise VERB dti-1406 59 4 a a DET dti-1406 59 5 circular circular ADJ dti-1406 59 6 pool pool NOUN dti-1406 59 7 ( ( PUNCT dti-1406 59 8 90 90 NUM dti-1406 59 9     SPACE dti-1406 59 10 cm cm NOUN dti-1406 59 11 diameter diameter NOUN dti-1406 59 12 and and CCONJ dti-1406 59 13 30 30 NUM dti-1406 59 14     SPACE dti-1406 59 15 cm cm NOUN dti-1406 59 16 height height NOUN dti-1406 59 17 ) ) PUNCT dti-1406 59 18 filled fill VERB dti-1406 59 19 with with ADP dti-1406 59 20 water water NOUN dti-1406 59 21 ( ( PUNCT dti-1406 59 22 22 22 NUM dti-1406 59 23 ° ° SYM dti-1406 59 24 c c NOUN dti-1406 59 25 ) ) PUNCT dti-1406 59 26 to to ADP dti-1406 59 27 a a DET dti-1406 59 28 depth depth NOUN dti-1406 59 29 of of ADP dti-1406 59 30 14 14 NUM dti-1406 59 31     SPACE dti-1406 59 32 cm cm NOUN dti-1406 59 33 and and CCONJ dti-1406 59 34 rendered render VERB dti-1406 59 35 opaque opaque NOUN dti-1406 59 36 by by ADP dti-1406 59 37 addition addition NOUN dti-1406 59 38 of of ADP dti-1406 59 39 small small ADJ dti-1406 59 40 black black ADJ dti-1406 59 41 balls ball NOUN dti-1406 59 42 . . PUNCT dti-1406 60 1 the the DET dti-1406 60 2 pool pool NOUN dti-1406 60 3 was be AUX dti-1406 60 4 located locate VERB dti-1406 60 5 in in ADP dti-1406 60 6 a a DET dti-1406 60 7 dimly dimly ADV dti-1406 60 8 lit light VERB dti-1406 60 9 , , PUNCT dti-1406 60 10 soundproof soundproof ADJ dti-1406 60 11 test test NOUN dti-1406 60 12 room room NOUN dti-1406 60 13 with with ADP dti-1406 60 14 various various ADJ dti-1406 60 15 visual visual ADJ dti-1406 60 16 cues cue NOUN dti-1406 60 17 , , PUNCT dti-1406 60 18 including include VERB dti-1406 60 19 a a DET dti-1406 60 20 white/ white/ ADV dti-1406 60 21 black black ADJ dti-1406 60 22 colored colored ADJ dti-1406 60 23 poster poster NOUN dti-1406 60 24 on on ADP dti-1406 60 25 the the DET dti-1406 60 26 wall wall NOUN dti-1406 60 27 , , PUNCT dti-1406 60 28 a a DET dti-1406 60 29 halogen halogen PROPN dti-1406 60 30 lamp lamp NOUN dti-1406 60 31 , , PUNCT dti-1406 60 32 a a DET dti-1406 60 33 camera camera NOUN dti-1406 60 34 , , PUNCT dti-1406 60 35 and and CCONJ dti-1406 60 36 the the DET dti-1406 60 37 experimenter experimenter NOUN dti-1406 60 38 . . PUNCT dti-1406 61 1 the the DET dti-1406 61 2 maze maze NOUN dti-1406 61 3 was be AUX dti-1406 61 4 divided divide VERB dti-1406 61 5 into into ADP dti-1406 61 6 four four NUM dti-1406 61 7 quadrants quadrant NOUN dti-1406 61 8 , , PUNCT dti-1406 61 9 and and CCONJ dti-1406 61 10 three three NUM dti-1406 61 11 equally equally ADV dti-1406 61 12 spaced space VERB dti-1406 61 13 points point NOUN dti-1406 61 14 served serve VERB dti-1406 61 15 as as ADP dti-1406 61 16 starting start VERB dti-1406 61 17 positions position NOUN dti-1406 61 18 around around ADP dti-1406 61 19 the the DET dti-1406 61 20 edge edge NOUN dti-1406 61 21 of of ADP dti-1406 61 22 the the DET dti-1406 61 23 pool pool NOUN dti-1406 61 24 . . PUNCT dti-1406 62 1 the the DET dti-1406 62 2 order order NOUN dti-1406 62 3 of of ADP dti-1406 62 4 the the DET dti-1406 62 5 release release NOUN dti-1406 62 6 positions position NOUN dti-1406 62 7 was be AUX dti-1406 62 8 varied varied ADJ dti-1406 62 9 systematically systematically ADV dti-1406 62 10 throughout throughout ADP dti-1406 62 11 the the DET dti-1406 62 12 experiment experiment NOUN dti-1406 62 13 . . PUNCT dti-1406 63 1 a a DET dti-1406 63 2 circular circular ADJ dti-1406 63 3 escape escape NOUN dti-1406 63 4 platform platform NOUN dti-1406 63 5 ( ( PUNCT dti-1406 63 6 6 6 NUM dti-1406 63 7     SPACE dti-1406 63 8 cm cm NOUN dti-1406 63 9 diameter diameter NOUN dti-1406 63 10 and and CCONJ dti-1406 63 11 12 12 NUM dti-1406 63 12     SPACE dti-1406 63 13 cm cm NOUN dti-1406 63 14 high high ADJ dti-1406 63 15 ) ) PUNCT dti-1406 63 16 was be AUX dti-1406 63 17 located locate VERB dti-1406 63 18 in in ADP dti-1406 63 19 one one NUM dti-1406 63 20 quadrant quadrant NOUN dti-1406 63 21 1 1 NUM dti-1406 63 22     SPACE dti-1406 63 23 cm cm NOUN dti-1406 63 24 above above ADP dti-1406 63 25 the the DET dti-1406 63 26 water water NOUN dti-1406 63 27 surface surface NOUN dti-1406 63 28 during during ADP dti-1406 63 29 the the DET dti-1406 63 30 familiarization familiarization NOUN dti-1406 63 31 session session NOUN dti-1406 63 32 and and CCONJ dti-1406 63 33 1 1 NUM dti-1406 63 34     SPACE dti-1406 63 35 cm cm NOUN dti-1406 63 36 below below ADP dti-1406 63 37 the the DET dti-1406 63 38 water water NOUN dti-1406 63 39 surface surface NOUN dti-1406 63 40 during during ADP dti-1406 63 41 the the DET dti-1406 63 42 other other ADJ dti-1406 63 43 sessions.17,20 sessions.17,20 ADJ dti-1406 63 44 video video NOUN dti-1406 63 45 tracking tracking NOUN dti-1406 63 46 was be AUX dti-1406 63 47 conducted conduct VERB dti-1406 63 48 with with ADP dti-1406 63 49 a a DET dti-1406 63 50 video video NOUN dti-1406 63 51 camera camera NOUN dti-1406 63 52 focused focus VERB dti-1406 63 53 on on ADP dti-1406 63 54 the the DET dti-1406 63 55 full full ADJ dti-1406 63 56 diameter diameter NOUN dti-1406 63 57 of of ADP dti-1406 63 58 the the DET dti-1406 63 59 pool pool NOUN dti-1406 63 60 . . PUNCT dti-1406 64 1 navigation navigation NOUN dti-1406 64 2 parameters parameter NOUN dti-1406 64 3 were be AUX dti-1406 64 4 analyzed analyze VERB dti-1406 64 5 using use VERB dti-1406 64 6 the the DET dti-1406 64 7 ethovision ethovision NOUN dti-1406 64 8 3.1 3.1 NUM dti-1406 64 9 video video NOUN dti-1406 64 10 analysis analysis NOUN dti-1406 64 11 system system NOUN dti-1406 64 12 ( ( PUNCT dti-1406 64 13 noldus noldus NOUN dti-1406 64 14 ) ) PUNCT dti-1406 64 15 . . PUNCT dti-1406 65 1 mice mouse NOUN dti-1406 65 2 were be AUX dti-1406 65 3 trained train VERB dti-1406 65 4 in in ADP dti-1406 65 5 mwm mwm NOUN dti-1406 65 6 five five NUM dti-1406 65 7 times time NOUN dti-1406 65 8 per per ADP dti-1406 65 9 day day NOUN dti-1406 65 10 ( ( PUNCT dti-1406 65 11 familiarization familiarization NOUN dti-1406 65 12 session session NOUN dti-1406 65 13 , , PUNCT dti-1406 65 14 s1 s1 NOUN dti-1406 65 15 , , PUNCT dti-1406 65 16 s2 s2 PROPN dti-1406 65 17 , , PUNCT dti-1406 65 18 s3 s3 PROPN dti-1406 65 19 , , PUNCT dti-1406 65 20 and and CCONJ dti-1406 65 21 s4 s4 PROPN dti-1406 65 22 ) ) PUNCT dti-1406 65 23 . . PUNCT dti-1406 66 1 one one NUM dti-1406 66 2 familiarization familiarization NOUN dti-1406 66 3 and and CCONJ dti-1406 66 4 four four NUM dti-1406 66 5 acquisition acquisition NOUN dti-1406 66 6 sessions session NOUN dti-1406 66 7 were be AUX dti-1406 66 8 carried carry VERB dti-1406 66 9 out out ADP dti-1406 66 10 using use VERB dti-1406 66 11 the the DET dti-1406 66 12 mwm mwm NOUN dti-1406 66 13 . . PUNCT dti-1406 66 14 during during ADP dti-1406 66 15 the the DET dti-1406 66 16 familiarization familiarization NOUN dti-1406 66 17 session session NOUN dti-1406 66 18 and and CCONJ dti-1406 66 19 acquisition acquisition NOUN dti-1406 66 20 phase phase NOUN dti-1406 66 21 of of ADP dti-1406 66 22 experiment experiment NOUN dti-1406 66 23 , , PUNCT dti-1406 66 24 each each DET dti-1406 66 25 mouse mouse NOUN dti-1406 66 26 underwent undergo VERB dti-1406 66 27 three three NUM dti-1406 66 28 trials trial NOUN dti-1406 66 29 . . PUNCT dti-1406 67 1 the the DET dti-1406 67 2 delay delay NOUN dti-1406 67 3 between between ADP dti-1406 67 4 trials trial NOUN dti-1406 67 5 was be AUX dti-1406 67 6 60 60 NUM dti-1406 67 7     SPACE dti-1406 67 8 seconds second NOUN dti-1406 67 9 , , PUNCT dti-1406 67 10 and and CCONJ dti-1406 67 11 a a DET dti-1406 67 12 1 1 NUM dti-1406 67 13 - - PUNCT dti-1406 67 14 day day NOUN dti-1406 67 15 interval interval NOUN dti-1406 67 16 was be AUX dti-1406 67 17 used use VERB dti-1406 67 18 between between ADP dti-1406 67 19 each each DET dti-1406 67 20 session session NOUN dti-1406 67 21 . . PUNCT dti-1406 68 1 for for ADP dti-1406 68 2 each each DET dti-1406 68 3 trial trial NOUN dti-1406 68 4 , , PUNCT dti-1406 68 5 the the DET dti-1406 68 6 mouse mouse NOUN dti-1406 68 7 was be AUX dti-1406 68 8 removed remove VERB dti-1406 68 9 from from ADP dti-1406 68 10 the the DET dti-1406 68 11 home home NOUN dti-1406 68 12 cage cage NOUN dti-1406 68 13 and and CCONJ dti-1406 68 14 placed place VERB dti-1406 68 15 in in ADP dti-1406 68 16 the the DET dti-1406 68 17 water water NOUN dti-1406 68 18 maze maze NOUN dti-1406 68 19 at at ADP dti-1406 68 20 one one NUM dti-1406 68 21 of of ADP dti-1406 68 22 three three NUM dti-1406 68 23 randomly randomly ADV dti-1406 68 24 determined determine VERB dti-1406 68 25 locations location NOUN dti-1406 68 26 with with ADP dti-1406 68 27 its its PRON dti-1406 68 28 head head NOUN dti-1406 68 29 facing face VERB dti-1406 68 30 the the DET dti-1406 68 31 center center NOUN dti-1406 68 32 of of ADP dti-1406 68 33 the the DET dti-1406 68 34 water water NOUN dti-1406 68 35 maze maze NOUN dti-1406 68 36 . . PUNCT dti-1406 69 1 after after SCONJ dti-1406 69 2 the the DET dti-1406 69 3 mouse mouse NOUN dti-1406 69 4 had have AUX dti-1406 69 5 found find VERB dti-1406 69 6 and and CCONJ dti-1406 69 7 climbed climb VERB dti-1406 69 8 onto onto ADP dti-1406 69 9 the the DET dti-1406 69 10 platform platform NOUN dti-1406 69 11 , , PUNCT dti-1406 69 12 the the DET dti-1406 69 13 trial trial NOUN dti-1406 69 14 was be AUX dti-1406 69 15 terminated terminate VERB dti-1406 69 16 and and CCONJ dti-1406 69 17 the the DET dti-1406 69 18 escape escape NOUN dti-1406 69 19 latency latency NOUN dti-1406 69 20 was be AUX dti-1406 69 21 recorded record VERB dti-1406 69 22 . . PUNCT dti-1406 70 1 if if SCONJ dti-1406 70 2 the the DET dti-1406 70 3 mouse mouse NOUN dti-1406 70 4 did do AUX dti-1406 70 5 not not PART dti-1406 70 6 climb climb VERB dti-1406 70 7 onto onto ADP dti-1406 70 8 the the DET dti-1406 70 9 platform platform NOUN dti-1406 70 10 in in ADP dti-1406 70 11 60 60 NUM dti-1406 70 12     SPACE dti-1406 70 13 seconds second NOUN dti-1406 70 14 , , PUNCT dti-1406 70 15 the the DET dti-1406 70 16 trial trial NOUN dti-1406 70 17 was be AUX dti-1406 70 18 terminated terminate VERB dti-1406 70 19 , , PUNCT dti-1406 70 20 and and CCONJ dti-1406 70 21 experimenter experimenter NOUN dti-1406 70 22 guided guide VERB dti-1406 70 23 the the DET dti-1406 70 24 mouse mouse NOUN dti-1406 70 25 to to ADP dti-1406 70 26 the the DET dti-1406 70 27 platform platform NOUN dti-1406 70 28 ; ; PUNCT dti-1406 70 29 an an DET dti-1406 70 30 escape escape NOUN dti-1406 70 31 latency latency NOUN dti-1406 70 32 of of ADP dti-1406 70 33 60 60 NUM dti-1406 70 34     SPACE dti-1406 70 35 seconds second NOUN dti-1406 70 36 was be AUX dti-1406 70 37 recorded.17,20 recorded.17,20 ADJ dti-1406 70 38 twenty twenty NUM dti-1406 70 39 - - PUNCT dti-1406 70 40 four four NUM dti-1406 70 41 hours hour NOUN dti-1406 70 42 after after SCONJ dti-1406 70 43 the the DET dti-1406 70 44 final final ADJ dti-1406 70 45 acquisition acquisition NOUN dti-1406 70 46 session session NOUN dti-1406 70 47 , , PUNCT dti-1406 70 48 a a DET dti-1406 70 49 “ " PUNCT dti-1406 70 50 probe probe NOUN dti-1406 70 51 trial trial NOUN dti-1406 70 52 ” " PUNCT dti-1406 70 53 was be AUX dti-1406 70 54 used use VERB dti-1406 70 55 to to PART dti-1406 70 56 assess assess VERB dti-1406 70 57 the the DET dti-1406 70 58 spatial spatial ADJ dti-1406 70 59 memory memory NOUN dti-1406 70 60 retention retention NOUN dti-1406 70 61 of of ADP dti-1406 70 62 the the DET dti-1406 70 63 location location NOUN dti-1406 70 64 of of ADP dti-1406 70 65 the the DET dti-1406 70 66 hidden hide VERB dti-1406 70 67 platform platform NOUN dti-1406 70 68 . . PUNCT dti-1406 71 1 during during ADP dti-1406 71 2 this this DET dti-1406 71 3 trial trial NOUN dti-1406 71 4 , , PUNCT dti-1406 71 5 the the DET dti-1406 71 6 platform platform NOUN dti-1406 71 7 was be AUX dti-1406 71 8 removed remove VERB dti-1406 71 9 from from ADP dti-1406 71 10 the the DET dti-1406 71 11 maze maze NOUN dti-1406 71 12 and and CCONJ dti-1406 71 13 the the DET dti-1406 71 14 mouse mouse NOUN dti-1406 71 15 was be AUX dti-1406 71 16 allowed allow VERB dti-1406 71 17 to to PART dti-1406 71 18 search search VERB dti-1406 71 19 the the DET dti-1406 71 20 pool pool NOUN dti-1406 71 21 for for ADP dti-1406 71 22 60 60 NUM dti-1406 71 23     SPACE dti-1406 71 24 seconds second NOUN dti-1406 71 25 . . PUNCT dti-1406 72 1 the the DET dti-1406 72 2 percent percent NOUN dti-1406 72 3 of of ADP dti-1406 72 4 time time NOUN dti-1406 72 5 spent spend VERB dti-1406 72 6 in in ADP dti-1406 72 7 each each DET dti-1406 72 8 quadrant quadrant NOUN dti-1406 72 9 was be AUX dti-1406 72 10 recorded.17,20 recorded.17,20 ADJ dti-1406 72 11 radial radial ADJ dti-1406 72 12 arm arm NOUN dti-1406 72 13 maze maze NOUN dti-1406 72 14 test test NOUN dti-1406 72 15 . . PUNCT dti-1406 73 1 the the DET dti-1406 73 2 experimental experimental ADJ dti-1406 73 3 device device NOUN dti-1406 73 4 comprised comprise VERB dti-1406 73 5 an an DET dti-1406 73 6 elevated elevated ADJ dti-1406 73 7 maze maze NOUN dti-1406 73 8 with with ADP dti-1406 73 9 eight eight NUM dti-1406 73 10 open open ADJ dti-1406 73 11 arms arm NOUN dti-1406 73 12 ( ( PUNCT dti-1406 73 13 32 32 NUM dti-1406 73 14 cm cm NOUN dti-1406 73 15 long long ADJ dti-1406 73 16 and and CCONJ dti-1406 73 17 5 5 NUM dti-1406 73 18 cm cm NOUN dti-1406 73 19 wide wide ADV dti-1406 73 20 ) ) PUNCT dti-1406 73 21 that that PRON dti-1406 73 22 led lead VERB dti-1406 73 23 to to ADP dti-1406 73 24 an an DET dti-1406 73 25 8 8 NUM dti-1406 73 26 - - PUNCT dti-1406 73 27 cm cm NOUN dti-1406 73 28 square square ADJ dti-1406 73 29 platform platform NOUN dti-1406 73 30 , , PUNCT dti-1406 73 31 which which PRON dti-1406 73 32 radiated radiate VERB dti-1406 73 33 from from ADP dti-1406 73 34 a a DET dti-1406 73 35 central central ADJ dti-1406 73 36 circular circular ADJ dti-1406 73 37 platform platform NOUN dti-1406 73 38 44 44 NUM dti-1406 73 39     SPACE dti-1406 73 40 cm cm NOUN dti-1406 73 41 in in ADP dti-1406 73 42 diameter diameter NOUN dti-1406 73 43 with with ADP dti-1406 73 44 1 1 NUM dti-1406 73 45 - - PUNCT dti-1406 73 46 cm cm NOUN dti-1406 73 47 high high ADJ dti-1406 73 48 sides side NOUN dti-1406 73 49 surrounding surround VERB dti-1406 73 50 each each DET dti-1406 73 51 arm.33 arm.33 ADJ dti-1406 73 52 a a DET dti-1406 73 53 small small ADJ dti-1406 73 54 cup cup NOUN dti-1406 73 55 , , PUNCT dti-1406 73 56 1 1 NUM dti-1406 73 57     SPACE dti-1406 73 58 cm cm NOUN dti-1406 73 59 in in ADP dti-1406 73 60 diameter diameter NOUN dti-1406 73 61 , , PUNCT dti-1406 73 62 was be AUX dti-1406 73 63 embedded embed VERB dti-1406 73 64 in in ADP dti-1406 73 65 each each DET dti-1406 73 66 distal distal ADJ dti-1406 73 67 platform platform NOUN dti-1406 73 68 , , PUNCT dti-1406 73 69 and and CCONJ dti-1406 73 70 it it PRON dti-1406 73 71 contained contain VERB dti-1406 73 72 a a DET dti-1406 73 73 hidden hidden ADJ dti-1406 73 74 10 10 NUM dti-1406 73 75 - - PUNCT dti-1406 73 76 mg mg NOUN dti-1406 73 77 noodle noodle NOUN dti-1406 73 78 used use VERB dti-1406 73 79 as as ADP dti-1406 73 80 reinforcement reinforcement NOUN dti-1406 73 81 . . PUNCT dti-1406 74 1 the the DET dti-1406 74 2 maze maze NOUN dti-1406 74 3 was be AUX dti-1406 74 4 oriented orient VERB dti-1406 74 5 in in ADP dti-1406 74 6 a a DET dti-1406 74 7 small small ADJ dti-1406 74 8 room room NOUN dti-1406 74 9 , , PUNCT dti-1406 74 10 which which PRON dti-1406 74 11 had have VERB dti-1406 74 12 four four NUM dti-1406 74 13 large large ADJ dti-1406 74 14 black black ADJ dti-1406 74 15 , , PUNCT dti-1406 74 16 white white ADJ dti-1406 74 17 , , PUNCT dti-1406 74 18 or or CCONJ dti-1406 74 19 black black ADJ dti-1406 74 20 and and CCONJ dti-1406 74 21 white white ADJ dti-1406 74 22 striped striped ADJ dti-1406 74 23 patterns pattern NOUN dti-1406 74 24 hung hang VERB dti-1406 74 25 on on ADP dti-1406 74 26 walls wall NOUN dti-1406 74 27 ; ; PUNCT dti-1406 74 28 these these DET dti-1406 74 29 patterns pattern NOUN dti-1406 74 30 provided provide VERB dti-1406 74 31 particularly particularly ADV dti-1406 74 32 salient salient ADJ dti-1406 74 33 visual visual ADJ dti-1406 74 34 extramaze extramaze NOUN dti-1406 74 35 cues cue NOUN dti-1406 74 36 . . PUNCT dti-1406 75 1 for for ADP dti-1406 75 2 further further ADJ dti-1406 75 3 details detail NOUN dti-1406 75 4 on on ADP dti-1406 75 5 the the DET dti-1406 75 6 apparatus apparatus NOUN dti-1406 75 7 , , PUNCT dti-1406 75 8 see see VERB dti-1406 75 9 beuzen beuzen INTJ dti-1406 75 10 et et PROPN dti-1406 75 11 al.33 al.33 PROPN dti-1406 75 12 twenty twenty NUM dti-1406 75 13 - - PUNCT dti-1406 75 14 four four NUM dti-1406 75 15 hours hour NOUN dti-1406 75 16 prior prior ADV dti-1406 75 17 to to ADP dti-1406 75 18 training training NOUN dti-1406 75 19 , , PUNCT dti-1406 75 20 the the DET dti-1406 75 21 mice mouse NOUN dti-1406 75 22 were be AUX dti-1406 75 23 deprived deprive VERB dti-1406 75 24 of of ADP dti-1406 75 25 food food NOUN dti-1406 75 26 but but CCONJ dti-1406 75 27 not not PART dti-1406 75 28 water water NOUN dti-1406 75 29 ; ; PUNCT dti-1406 75 30 their their PRON dti-1406 75 31 weight weight NOUN dti-1406 75 32 loss loss NOUN dti-1406 75 33 reached reach VERB dti-1406 75 34 15%–20 15%–20 NUM dti-1406 75 35 % % NOUN dti-1406 75 36 of of ADP dti-1406 75 37 the the DET dti-1406 75 38 initial initial ADJ dti-1406 75 39 body body NOUN dti-1406 75 40 weight weight NOUN dti-1406 75 41 by by ADP dti-1406 75 42 the the DET dti-1406 75 43 start start NOUN dti-1406 75 44 of of ADP dti-1406 75 45 the the DET dti-1406 75 46 testing testing NOUN dti-1406 75 47 . . PUNCT dti-1406 76 1 the the DET dti-1406 76 2 ram ram NOUN dti-1406 76 3 procedure procedure NOUN dti-1406 76 4 was be AUX dti-1406 76 5 applied apply VERB dti-1406 76 6 according accord VERB dti-1406 76 7 to to ADP dti-1406 76 8 belzung belzung PROPN dti-1406 76 9 et et PROPN dti-1406 76 10 al.34 al.34 PROPN dti-1406 76 11 the the DET dti-1406 76 12 mice mouse NOUN dti-1406 76 13 were be AUX dti-1406 76 14 first first ADV dti-1406 76 15 subjected subject VERB dti-1406 76 16 to to ADP dti-1406 76 17 two two NUM dti-1406 76 18 pretraining pretraine VERB dti-1406 76 19 sessions session NOUN dti-1406 76 20 at at ADP dti-1406 76 21 24 24 NUM dti-1406 76 22 - - PUNCT dti-1406 76 23 hour hour NOUN dti-1406 76 24 intervals interval NOUN dti-1406 76 25 . . PUNCT dti-1406 77 1 groups group NOUN dti-1406 77 2 of of ADP dti-1406 77 3 four four NUM dti-1406 77 4 mice mouse NOUN dti-1406 77 5 were be AUX dti-1406 77 6 placed place VERB dti-1406 77 7 on on ADP dti-1406 77 8 the the DET dti-1406 77 9 maze maze NOUN dti-1406 77 10 at at ADP dti-1406 77 11 the the DET dti-1406 77 12 same same ADJ dti-1406 77 13 time time NOUN dti-1406 77 14 and and CCONJ dti-1406 77 15 for for ADP dti-1406 77 16 20 20 NUM dti-1406 77 17     SPACE dti-1406 77 18 minutes minute NOUN dti-1406 77 19 per per ADP dti-1406 77 20 session session NOUN dti-1406 77 21 ; ; PUNCT dti-1406 77 22 the the DET dti-1406 77 23 mice mouse NOUN dti-1406 77 24 could could AUX dti-1406 77 25 freely freely ADV dti-1406 77 26 explore explore VERB dti-1406 77 27 the the DET dti-1406 77 28 eight eight NUM dti-1406 77 29 arms arm NOUN dti-1406 77 30 , , PUNCT dti-1406 77 31 which which PRON dti-1406 77 32 contained contain VERB dti-1406 77 33 abundant abundant ADJ dti-1406 77 34 food food NOUN dti-1406 77 35 . . PUNCT dti-1406 78 1 following follow VERB dti-1406 78 2 pretraining pretraine VERB dti-1406 78 3 , , PUNCT dti-1406 78 4 the the DET dti-1406 78 5 mice mouse NOUN dti-1406 78 6 were be AUX dti-1406 78 7 subjected subject VERB dti-1406 78 8 to to ADP dti-1406 78 9 five five NUM dti-1406 78 10 training training NOUN dti-1406 78 11 sessions session NOUN dti-1406 78 12 at at ADP dti-1406 78 13 90 90 NUM dti-1406 78 14 - - PUNCT dti-1406 78 15 minute minute NOUN dti-1406 78 16 intervals interval NOUN dti-1406 78 17 . . PUNCT dti-1406 79 1 after after ADP dti-1406 79 2 baiting bait VERB dti-1406 79 3 the the DET dti-1406 79 4 eight eight NUM dti-1406 79 5 arms arm NOUN dti-1406 79 6 with with ADP dti-1406 79 7 10 10 NUM dti-1406 79 8 - - PUNCT dti-1406 79 9 mg mg NOUN dti-1406 79 10 noodles noodle NOUN dti-1406 79 11 , , PUNCT dti-1406 79 12 a a DET dti-1406 79 13 mouse mouse NOUN dti-1406 79 14 was be AUX dti-1406 79 15 placed place VERB dti-1406 79 16 on on ADP dti-1406 79 17 the the DET dti-1406 79 18 central central ADJ dti-1406 79 19 platform platform NOUN dti-1406 79 20 . . PUNCT dti-1406 80 1 sessions session NOUN dti-1406 80 2 were be AUX dti-1406 80 3 terminated terminate VERB dti-1406 80 4 http://www.la-press.com http://www.la-press.com X dti-1406 80 5 http://www.la-press.com/drug-target-insights-journal-j23 http://www.la-press.com/drug-target-insights-journal-j23 PROPN dti-1406 80 6 7 7 PROPN dti-1406 80 7 - - SYM dti-1406 80 8 ni ni NOUN dti-1406 80 9 and and CCONJ dti-1406 80 10 odq odq NOUN dti-1406 80 11 disturbs disturb VERB dti-1406 80 12 memory memory NOUN dti-1406 80 13 in in ADP dti-1406 80 14 the the DET dti-1406 80 15 elevated elevated ADJ dti-1406 80 16 plus plus CCONJ dti-1406 80 17 maze maze NOUN dti-1406 80 18 3drug 3drug NUM dti-1406 80 19 target target NOUN dti-1406 80 20 insights insight VERB dti-1406 80 21 2015:9 2015:9 NUM dti-1406 80 22 when when SCONJ dti-1406 80 23 the the DET dti-1406 80 24 animal animal NOUN dti-1406 80 25 had have AUX dti-1406 80 26 visited visit VERB dti-1406 80 27 all all DET dti-1406 80 28 eight eight NUM dti-1406 80 29 arms arm NOUN dti-1406 80 30 and and CCONJ dti-1406 80 31 consumed consume VERB dti-1406 80 32 the the DET dti-1406 80 33 rewards reward NOUN dti-1406 80 34 , , PUNCT dti-1406 80 35 after after SCONJ dti-1406 80 36 16 16 NUM dti-1406 80 37 arms arm NOUN dti-1406 80 38 were be AUX dti-1406 80 39 visited visit VERB dti-1406 80 40 ( ( PUNCT dti-1406 80 41 regardless regardless ADV dti-1406 80 42 of of ADP dti-1406 80 43 which which PRON dti-1406 80 44 arms arm NOUN dti-1406 80 45 ) ) PUNCT dti-1406 80 46 , , PUNCT dti-1406 80 47 or or CCONJ dti-1406 80 48 after after ADP dti-1406 80 49 a a DET dti-1406 80 50 maximum maximum NOUN dti-1406 80 51 of of ADP dti-1406 80 52 15 15 NUM dti-1406 80 53     SPACE dti-1406 80 54 minutes minute NOUN dti-1406 80 55 . . PUNCT dti-1406 81 1 an an DET dti-1406 81 2 error error NOUN dti-1406 81 3 was be AUX dti-1406 81 4 recorded record VERB dti-1406 81 5 when when SCONJ dti-1406 81 6 the the DET dti-1406 81 7 mouse mouse NOUN dti-1406 81 8 entered enter VERB dti-1406 81 9 an an DET dti-1406 81 10 arm arm NOUN dti-1406 81 11 previously previously ADV dti-1406 81 12 visited visit VERB dti-1406 81 13 during during ADP dti-1406 81 14 the the DET dti-1406 81 15 retention retention NOUN dti-1406 81 16 session session NOUN dti-1406 81 17 . . PUNCT dti-1406 82 1 the the DET dti-1406 82 2 total total ADJ dti-1406 82 3 number number NOUN dti-1406 82 4 of of ADP dti-1406 82 5 errors error NOUN dti-1406 82 6 and and CCONJ dti-1406 82 7 the the DET dti-1406 82 8 latency latency NOUN dti-1406 82 9 of of ADP dti-1406 82 10 the the DET dti-1406 82 11 retention retention NOUN dti-1406 82 12 session session NOUN dti-1406 82 13 ( ( PUNCT dti-1406 82 14 time time NOUN dti-1406 82 15 taken take VERB dti-1406 82 16 to to PART dti-1406 82 17 complete complete VERB dti-1406 82 18 the the DET dti-1406 82 19 task task NOUN dti-1406 82 20 ) ) PUNCT dti-1406 82 21 were be AUX dti-1406 82 22 recorded.34 recorded.34 PROPN dti-1406 82 23 drug drug NOUN dti-1406 82 24 administration administration NOUN dti-1406 82 25 . . PUNCT dti-1406 83 1 7 7 NUM dti-1406 83 2 - - PUNCT dti-1406 83 3 ni ni ADJ dti-1406 83 4 , , PUNCT dti-1406 83 5 odq odq NOUN dti-1406 83 6 , , PUNCT dti-1406 83 7 and and CCONJ dti-1406 83 8 l l NOUN dti-1406 83 9 - - NOUN dti-1406 83 10 arginine arginine NOUN dti-1406 83 11 were be AUX dti-1406 83 12 procured procure VERB dti-1406 83 13 from from ADP dti-1406 83 14 sigma sigma PROPN dti-1406 83 15 chemical chemical NOUN dti-1406 83 16 company company NOUN dti-1406 83 17 . . PUNCT dti-1406 84 1 odq odq NOUN dti-1406 84 2 and and CCONJ dti-1406 84 3 l l NOUN dti-1406 84 4 - - NOUN dti-1406 84 5 arginine arginine NOUN dti-1406 84 6 were be AUX dti-1406 84 7 dissolved dissolve VERB dti-1406 84 8 in in ADP dti-1406 84 9 saline saline NOUN dti-1406 84 10 , , PUNCT dti-1406 84 11 whereas whereas SCONJ dti-1406 84 12 7 7 NUM dti-1406 84 13 - - PUNCT dti-1406 84 14 ni ni PROPN dti-1406 84 15 was be AUX dti-1406 84 16 dissolved dissolve VERB dti-1406 84 17 in in ADP dti-1406 84 18 saline saline NOUN dti-1406 84 19 supplemented supplement VERB dti-1406 84 20 with with ADP dti-1406 84 21 10 10 NUM dti-1406 84 22 % % NOUN dti-1406 84 23 dimethylsulfoxide dimethylsulfoxide NOUN dti-1406 84 24 ( ( PUNCT dti-1406 84 25 dmso dmso NOUN dti-1406 84 26 ) ) PUNCT dti-1406 84 27 . . PUNCT dti-1406 85 1 all all DET dti-1406 85 2 drugs drug NOUN dti-1406 85 3 were be AUX dti-1406 85 4 freshly freshly ADV dti-1406 85 5 prepared prepare VERB dti-1406 85 6 and and CCONJ dti-1406 85 7 administered administer VERB dti-1406 85 8 in in ADP dti-1406 85 9 a a DET dti-1406 85 10 volume volume NOUN dti-1406 85 11 of of ADP dti-1406 85 12 0.1 0.1 NUM dti-1406 85 13     SPACE dti-1406 85 14 ml ml NOUN dti-1406 85 15 per per ADP dti-1406 85 16 10 10 NUM dti-1406 85 17     SPACE dti-1406 85 18 g g NOUN dti-1406 85 19 body body NOUN dti-1406 85 20 weight weight NOUN dti-1406 85 21 . . PUNCT dti-1406 86 1 the the DET dti-1406 86 2 control control NOUN dti-1406 86 3 groups group NOUN dti-1406 86 4 received receive VERB dti-1406 86 5 the the DET dti-1406 86 6 same same ADJ dti-1406 86 7 volume volume NOUN dti-1406 86 8 of of ADP dti-1406 86 9 vehicle vehicle NOUN dti-1406 86 10 . . PUNCT dti-1406 87 1 7 7 NUM dti-1406 87 2 - - SYM dti-1406 87 3 ni ni PROPN dti-1406 87 4 ( ( PUNCT dti-1406 87 5 15 15 NUM dti-1406 87 6     SPACE dti-1406 87 7 mg mg PROPN dti-1406 87 8 / / SYM dti-1406 87 9 kg kg PROPN dti-1406 87 10 ) ) PUNCT dti-1406 87 11 , , PUNCT dti-1406 87 12 odq odq NOUN dti-1406 87 13 ( ( PUNCT dti-1406 87 14 3 3 NUM dti-1406 87 15 and and CCONJ dti-1406 87 16 10 10 NUM dti-1406 87 17     SPACE dti-1406 87 18 mg mg PROPN dti-1406 87 19 / / SYM dti-1406 87 20 kg kg PROPN dti-1406 87 21 ) ) PUNCT dti-1406 87 22 , , PUNCT dti-1406 87 23 l l NOUN dti-1406 87 24 - - NOUN dti-1406 87 25 arginine arginine NOUN dti-1406 87 26 , , PUNCT dti-1406 87 27 or or CCONJ dti-1406 87 28 the the DET dti-1406 87 29 vehicle vehicle NOUN dti-1406 87 30 was be AUX dti-1406 87 31 administered administer VERB dti-1406 87 32 via via ADP dti-1406 87 33 an an DET dti-1406 87 34 intraperitoneal intraperitoneal NOUN dti-1406 87 35 ( ( PUNCT dti-1406 87 36 i.p i.p PROPN dti-1406 87 37 . . PROPN dti-1406 87 38 ) ) PUNCT dti-1406 87 39 injection injection NOUN dti-1406 87 40 30 30 NUM dti-1406 87 41 , , PUNCT dti-1406 87 42 30 30 NUM dti-1406 87 43 , , PUNCT dti-1406 87 44 and and CCONJ dti-1406 87 45 60 60 NUM dti-1406 87 46     SPACE dti-1406 87 47 minutes minute NOUN dti-1406 87 48 , , PUNCT dti-1406 87 49 respectively respectively ADV dti-1406 87 50 , , PUNCT dti-1406 87 51 prior prior ADV dti-1406 87 52 to to ADP dti-1406 87 53 the the DET dti-1406 87 54 first first ADJ dti-1406 87 55 session session NOUN dti-1406 87 56 ( ( PUNCT dti-1406 87 57 acquisition acquisition NOUN dti-1406 87 58 session session NOUN dti-1406 87 59 , , PUNCT dti-1406 87 60 day day NOUN dti-1406 87 61 1 1 NUM dti-1406 87 62 ) ) PUNCT dti-1406 87 63 of of ADP dti-1406 87 64 mepm mepm NOUN dti-1406 87 65 test test NOUN dti-1406 87 66 , , PUNCT dti-1406 87 67 prior prior ADV dti-1406 87 68 to to ADP dti-1406 87 69 the the DET dti-1406 87 70 retention retention NOUN dti-1406 87 71 trial trial NOUN dti-1406 87 72 of of ADP dti-1406 87 73 ram ram NOUN dti-1406 87 74 test test NOUN dti-1406 87 75 , , PUNCT dti-1406 87 76 and and CCONJ dti-1406 87 77 for for ADP dti-1406 87 78 6 6 NUM dti-1406 87 79 days day NOUN dti-1406 87 80 prior prior ADV dti-1406 87 81 to to ADP dti-1406 87 82 the the DET dti-1406 87 83 acquisition acquisition NOUN dti-1406 87 84 trials trial NOUN dti-1406 87 85 and and CCONJ dti-1406 87 86 the the DET dti-1406 87 87 probe probe NOUN dti-1406 87 88 trial trial NOUN dti-1406 87 89 of of ADP dti-1406 87 90 the the DET dti-1406 87 91 mwm mwm NOUN dti-1406 87 92 test test NOUN dti-1406 87 93 . . PUNCT dti-1406 88 1 the the DET dti-1406 88 2 number number NOUN dti-1406 88 3 of of ADP dti-1406 88 4 animals animal NOUN dti-1406 88 5 per per ADP dti-1406 88 6 group group NOUN dti-1406 88 7 ranged range VERB dti-1406 88 8 from from ADP dti-1406 88 9 6 6 NUM dti-1406 88 10 to to PART dti-1406 88 11 7 7 NUM dti-1406 88 12 . . PUNCT dti-1406 88 13 effective effective ADJ dti-1406 88 14 dose dose NOUN dti-1406 88 15 of of ADP dti-1406 88 16 each each DET dti-1406 88 17 drug drug NOUN dti-1406 88 18 was be AUX dti-1406 88 19 selected select VERB dti-1406 88 20 according accord VERB dti-1406 88 21 to to ADP dti-1406 88 22 previous previous ADJ dti-1406 88 23 behavioral behavioral ADJ dti-1406 88 24 and and CCONJ dti-1406 88 25 neurochemical neurochemical ADJ dti-1406 88 26 studies.3,35–37 studies.3,35–37 PROPN dti-1406 88 27 statistics statistic NOUN dti-1406 88 28 . . PUNCT dti-1406 89 1 a a DET dti-1406 89 2 two two NUM dti-1406 89 3 - - PUNCT dti-1406 89 4 way way NOUN dti-1406 89 5 analysis analysis NOUN dti-1406 89 6 of of ADP dti-1406 89 7 variance variance NOUN dti-1406 89 8 ( ( PUNCT dti-1406 89 9 anova anova PROPN dti-1406 89 10 ) ) PUNCT dti-1406 89 11 and and CCONJ dti-1406 89 12 post post VERB dti-1406 89 13 hoc hoc X dti-1406 89 14 tukey tukey NOUN dti-1406 89 15 test test NOUN dti-1406 89 16 were be AUX dti-1406 89 17 used use VERB dti-1406 89 18 to to PART dti-1406 89 19 analyze analyze VERB dti-1406 89 20 the the DET dti-1406 89 21 mepm mepm NOUN dti-1406 89 22 , , PUNCT dti-1406 89 23 mwm mwm NOUN dti-1406 89 24 , , PUNCT dti-1406 89 25 and and CCONJ dti-1406 89 26 ram ram NOUN dti-1406 89 27 tests test NOUN dti-1406 89 28 . . PUNCT dti-1406 90 1 the the DET dti-1406 90 2 data datum NOUN dti-1406 90 3 are be AUX dti-1406 90 4 expressed express VERB dti-1406 90 5 as as ADP dti-1406 90 6 the the DET dti-1406 90 7 mean mean PROPN dti-1406 90 8 ± ± NUM dti-1406 90 9 sem sem NOUN dti-1406 90 10 . . PUNCT dti-1406 91 1 p p X dti-1406 91 2     SPACE dti-1406 91 3 , , PUNCT dti-1406 91 4     SPACE dti-1406 91 5 0.05 0.05 NUM dti-1406 91 6 was be AUX dti-1406 91 7 considered consider VERB dti-1406 91 8 statistically statistically ADV dti-1406 91 9 significant significant ADJ dti-1406 91 10 . . PUNCT dti-1406 92 1 results result VERB dti-1406 92 2 effects effect NOUN dti-1406 92 3 of of ADP dti-1406 92 4 7 7 NUM dti-1406 92 5 - - PUNCT dti-1406 92 6 ni ni PROPN dti-1406 92 7 , , PUNCT dti-1406 92 8 odq odq NOUN dti-1406 92 9 , , PUNCT dti-1406 92 10 and and CCONJ dti-1406 92 11 7 7 NUM dti-1406 92 12 - - PUNCT dti-1406 92 13 ni ni PROPN dti-1406 92 14 ± ± PROPN dti-1406 92 15 l l NOUN dti-1406 92 16 - - NOUN dti-1406 92 17 arginine arginine NOUN dti-1406 92 18 on on ADP dti-1406 92 19 learning learning NOUN dti-1406 92 20 and and CCONJ dti-1406 92 21 memory memory NOUN dti-1406 92 22 in in ADP dti-1406 92 23 the the DET dti-1406 92 24 mepm mepm NOUN dti-1406 92 25 test test NOUN dti-1406 92 26 . . PUNCT dti-1406 93 1 when when SCONJ dti-1406 93 2 7 7 NUM dti-1406 93 3 - - SYM dti-1406 93 4 ni ni NOUN dti-1406 93 5 ( ( PUNCT dti-1406 93 6 15 15 NUM dti-1406 93 7     SPACE dti-1406 93 8 mg mg PROPN dti-1406 93 9 / / SYM dti-1406 93 10 kg kg PROPN dti-1406 93 11 ) ) PUNCT dti-1406 93 12 , , PUNCT dti-1406 93 13 odq odq NOUN dti-1406 93 14 ( ( PUNCT dti-1406 93 15 3 3 NUM dti-1406 93 16 and and CCONJ dti-1406 93 17 10 10 NUM dti-1406 93 18     SPACE dti-1406 93 19 mg mg PROPN dti-1406 93 20 / / SYM dti-1406 93 21 kg kg PROPN dti-1406 93 22 ) ) PUNCT dti-1406 93 23 , , PUNCT dti-1406 93 24 or or CCONJ dti-1406 93 25 7 7 NUM dti-1406 93 26 - - PUNCT dti-1406 93 27 ni ni NOUN dti-1406 93 28 ( ( PUNCT dti-1406 93 29 15 15 NUM dti-1406 93 30     SPACE dti-1406 93 31 mg mg PROPN dti-1406 93 32 / / SYM dti-1406 93 33 kg kg NOUN dti-1406 93 34 ) ) PUNCT dti-1406 93 35 + + CCONJ dti-1406 93 36 l l NOUN dti-1406 93 37 - - NOUN dti-1406 93 38 arg arg NOUN dti-1406 93 39 ( ( PUNCT dti-1406 93 40 100 100 NUM dti-1406 93 41     SPACE dti-1406 93 42 mg mg PROPN dti-1406 93 43 / / SYM dti-1406 93 44 kg kg PROPN dti-1406 93 45 ) ) PUNCT dti-1406 93 46 was be AUX dti-1406 93 47 administered administer VERB dti-1406 93 48 prior prior ADV dti-1406 93 49 to to ADP dti-1406 93 50 the the DET dti-1406 93 51 acquisition acquisition NOUN dti-1406 93 52 session session NOUN dti-1406 93 53 ( ( PUNCT dti-1406 93 54 training training NOUN dti-1406 93 55 ; ; PUNCT dti-1406 93 56 day day NOUN dti-1406 93 57 1 1 NUM dti-1406 93 58 ) ) PUNCT dti-1406 93 59 , , PUNCT dti-1406 93 60 there there PRON dti-1406 93 61 was be VERB dti-1406 93 62 no no DET dti-1406 93 63 significant significant ADJ dti-1406 93 64 effect effect NOUN dti-1406 93 65 of of ADP dti-1406 93 66 the the DET dti-1406 93 67 drugs drug NOUN dti-1406 93 68 [ [ X dti-1406 93 69 f(3,29 f(3,29 NOUN dti-1406 93 70 ) ) PUNCT dti-1406 93 71     SPACE dti-1406 94 1 = = NOUN dti-1406 94 2     SPACE dti-1406 94 3 1.81 1.81 NUM dti-1406 94 4 ; ; PUNCT dti-1406 94 5 fig fig NOUN dti-1406 94 6 . . PUNCT dti-1406 95 1 1a 1a NOUN dti-1406 95 2 ] ] PUNCT dti-1406 95 3 or or CCONJ dti-1406 95 4 their their PRON dti-1406 95 5 combination combination NOUN dti-1406 95 6 [ [ X dti-1406 95 7 f(1,29 f(1,29 X dti-1406 95 8 ) ) PUNCT dti-1406 95 9     SPACE dti-1406 95 10 = = NOUN dti-1406 95 11     SPACE dti-1406 95 12 1.71 1.71 NUM dti-1406 95 13 ; ; PUNCT dti-1406 95 14 fig fig NOUN dti-1406 95 15 . . PUNCT dti-1406 96 1 1a 1a NOUN dti-1406 96 2 ] ] X dti-1406 96 3 in in ADP dti-1406 96 4 the the DET dti-1406 96 5 mepm mepm NOUN dti-1406 96 6 test test NOUN dti-1406 96 7 . . PUNCT dti-1406 97 1 there there PRON dti-1406 97 2 was be VERB dti-1406 97 3 a a DET dti-1406 97 4 significant significant ADJ dti-1406 97 5 effect effect NOUN dti-1406 97 6 of of ADP dti-1406 97 7 the the DET dti-1406 97 8 drugs drug NOUN dti-1406 97 9 [ [ X dti-1406 97 10 f(3,29 f(3,29 NOUN dti-1406 97 11 ) ) PUNCT dti-1406 97 12     SPACE dti-1406 98 1 = = NOUN dti-1406 98 2     SPACE dti-1406 98 3 7.07 7.07 NUM dti-1406 98 4 , , PUNCT dti-1406 98 5 p p X dti-1406 98 6     SPACE dti-1406 98 7 = = NOUN dti-1406 98 8     SPACE dti-1406 98 9 0.001 0.001 NUM dti-1406 98 10 ; ; PUNCT dti-1406 98 11 fig fig NOUN dti-1406 98 12 . . PUNCT dti-1406 98 13     SPACE dti-1406 98 14 1b 1b NUM dti-1406 98 15 ] ] PUNCT dti-1406 98 16 and and CCONJ dti-1406 98 17 their their PRON dti-1406 98 18 combination combination NOUN dti-1406 98 19 [ [ X dti-1406 98 20 f(1,29 f(1,29 X dti-1406 98 21 ) ) PUNCT dti-1406 98 22     SPACE dti-1406 98 23 = = NOUN dti-1406 98 24     SPACE dti-1406 98 25 14.17 14.17 NUM dti-1406 98 26 , , PUNCT dti-1406 98 27 p p X dti-1406 98 28     SPACE dti-1406 98 29 , , PUNCT dti-1406 98 30     SPACE dti-1406 98 31 0.001 0.001 NUM dti-1406 98 32 ; ; PUNCT dti-1406 98 33 fig fig NOUN dti-1406 98 34 . . PUNCT dti-1406 99 1 1b 1b NUM dti-1406 99 2 ] ] PUNCT dti-1406 99 3 on on ADP dti-1406 99 4 the the DET dti-1406 99 5 second second ADJ dti-1406 99 6 - - PUNCT dti-1406 99 7 day day NOUN dti-1406 99 8 latency latency NOUN dti-1406 99 9 in in ADP dti-1406 99 10 the the DET dti-1406 99 11 mepm mepm NOUN dti-1406 99 12 test test NOUN dti-1406 99 13 . . PUNCT dti-1406 100 1 odq odq NOUN dti-1406 100 2 ( ( PUNCT dti-1406 100 3 3 3 NUM dti-1406 100 4     SPACE dti-1406 100 5 mg mg PROPN dti-1406 100 6 / / SYM dti-1406 100 7 kg kg PROPN dti-1406 100 8 ) ) PUNCT dti-1406 100 9 and and CCONJ dti-1406 100 10 7 7 NUM dti-1406 100 11 - - PUNCT dti-1406 100 12 ni ni PROPN dti-1406 100 13 ( ( PUNCT dti-1406 100 14 15 15 NUM dti-1406 100 15     SPACE dti-1406 100 16 mg mg PROPN dti-1406 100 17 / / SYM dti-1406 100 18 kg kg NOUN dti-1406 100 19 ) ) PUNCT dti-1406 100 20 significantly significantly ADV dti-1406 100 21 prolonged prolong VERB dti-1406 100 22 the the DET dti-1406 100 23 latency latency NOUN dti-1406 100 24 ( ( PUNCT dti-1406 100 25 tl2 tl2 PROPN dti-1406 100 26 ) ) PUNCT dti-1406 100 27 on on ADP dti-1406 100 28 the the DET dti-1406 100 29 second second ADJ dti-1406 100 30 day day NOUN dti-1406 100 31 compared compare VERB dti-1406 100 32 with with ADP dti-1406 100 33 the the DET dti-1406 100 34 control control NOUN dti-1406 100 35 group group NOUN dti-1406 100 36 when when SCONJ dti-1406 100 37 the the DET dti-1406 100 38 drugs drug NOUN dti-1406 100 39 were be AUX dti-1406 100 40 administered administer VERB dti-1406 100 41 prior prior ADV dti-1406 100 42 to to ADP dti-1406 100 43 the the DET dti-1406 100 44 acquisition acquisition NOUN dti-1406 100 45 session session NOUN dti-1406 100 46 ( ( PUNCT dti-1406 100 47 p p X dti-1406 100 48     SPACE dti-1406 100 49 , , PUNCT dti-1406 100 50     SPACE dti-1406 100 51 0.05 0.05 NUM dti-1406 100 52 and and CCONJ dti-1406 100 53 p p X dti-1406 100 54     SPACE dti-1406 100 55 , , PUNCT dti-1406 100 56     SPACE dti-1406 100 57 0.01 0.01 NUM dti-1406 100 58 , , PUNCT dti-1406 100 59 respectively respectively ADV dti-1406 100 60 ; ; PUNCT dti-1406 100 61 fig fig NOUN dti-1406 100 62 . . PUNCT dti-1406 100 63 1b 1b NUM dti-1406 100 64 ) ) PUNCT dti-1406 100 65 . . PUNCT dti-1406 101 1 l l NOUN dti-1406 101 2 - - NOUN dti-1406 101 3 arginine arginine NOUN dti-1406 101 4 ( ( PUNCT dti-1406 101 5 100 100 NUM dti-1406 101 6     SPACE dti-1406 101 7 mg mg PROPN dti-1406 101 8 / / SYM dti-1406 101 9 kg kg PROPN dti-1406 101 10 ) ) PUNCT dti-1406 101 11 combined combine VERB dti-1406 101 12 with with ADP dti-1406 101 13 7 7 NUM dti-1406 101 14 - - PUNCT dti-1406 101 15 ni ni NOUN dti-1406 101 16 ( ( PUNCT dti-1406 101 17 15 15 NUM dti-1406 101 18     SPACE dti-1406 101 19 mg mg PROPN dti-1406 101 20 / / SYM dti-1406 101 21 kg kg NOUN dti-1406 101 22 ) ) PUNCT dti-1406 101 23 significantly significantly ADV dti-1406 101 24 shortened shorten VERB dti-1406 101 25 the the DET dti-1406 101 26 tl2 tl2 NOUN dti-1406 101 27 compared compare VERB dti-1406 101 28 with with ADP dti-1406 101 29 7 7 NUM dti-1406 101 30 - - PUNCT dti-1406 101 31 ni ni NOUN dti-1406 101 32 ( ( PUNCT dti-1406 101 33 15 15 NUM dti-1406 101 34     SPACE dti-1406 101 35 mg mg PROPN dti-1406 101 36 / / SYM dti-1406 101 37 kg kg PROPN dti-1406 101 38 ) ) PUNCT dti-1406 101 39 alone alone ADV dti-1406 101 40 ( ( PUNCT dti-1406 101 41 p p X dti-1406 101 42     SPACE dti-1406 101 43 , , PUNCT dti-1406 101 44     SPACE dti-1406 101 45 0.001 0.001 NUM dti-1406 101 46 ; ; PUNCT dti-1406 101 47 fig fig NOUN dti-1406 101 48 . . PUNCT dti-1406 101 49 1b 1b NUM dti-1406 101 50 ) ) PUNCT dti-1406 101 51 . . PUNCT dti-1406 102 1 effects effect NOUN dti-1406 102 2 of of ADP dti-1406 102 3 7 7 NUM dti-1406 102 4 - - PUNCT dti-1406 102 5 ni ni ADJ dti-1406 102 6 , , PUNCT dti-1406 102 7 odq odq NOUN dti-1406 102 8 , , PUNCT dti-1406 102 9 and and CCONJ dti-1406 102 10 7 7 NUM dti-1406 102 11 - - PUNCT dti-1406 102 12 ni ni PROPN dti-1406 102 13 ± ± PROPN dti-1406 102 14 l l NOUN dti-1406 102 15 - - NOUN dti-1406 102 16 arginine arginine NOUN dti-1406 102 17 on on ADP dti-1406 102 18 learning learning NOUN dti-1406 102 19 and and CCONJ dti-1406 102 20 memory memory NOUN dti-1406 102 21 in in ADP dti-1406 102 22 the the DET dti-1406 102 23 mwm mwm NOUN dti-1406 102 24 test test NOUN dti-1406 102 25 . . PUNCT dti-1406 103 1 there there PRON dti-1406 103 2 was be VERB dti-1406 103 3 a a DET dti-1406 103 4 significant significant ADJ dti-1406 103 5 difference difference NOUN dti-1406 103 6 in in ADP dti-1406 103 7 the the DET dti-1406 103 8 escape escape NOUN dti-1406 103 9 latency latency NOUN dti-1406 103 10 in in ADP dti-1406 103 11 the the DET dti-1406 103 12 first first ADJ dti-1406 103 13 , , PUNCT dti-1406 103 14 second second ADJ dti-1406 103 15 , , PUNCT dti-1406 103 16 third third ADJ dti-1406 103 17 , , PUNCT dti-1406 103 18 and and CCONJ dti-1406 103 19 fourth fourth ADJ dti-1406 103 20 sessions session NOUN dti-1406 103 21 during during ADP dti-1406 103 22 the the DET dti-1406 103 23 evaluation evaluation NOUN dti-1406 103 24 of of ADP dti-1406 103 25 the the DET dti-1406 103 26 drug drug NOUN dti-1406 103 27 groups group NOUN dti-1406 103 28 [ [ X dti-1406 103 29 f(3,35 f(3,35 ADJ dti-1406 103 30 ) ) PUNCT dti-1406 103 31     SPACE dti-1406 104 1 = = NOUN dti-1406 104 2     SPACE dti-1406 104 3 6.58 6.58 NUM dti-1406 104 4 , , PUNCT dti-1406 104 5 p p X dti-1406 104 6     SPACE dti-1406 104 7 = = NOUN dti-1406 104 8     SPACE dti-1406 104 9 0.001 0.001 NUM dti-1406 104 10 ; ; PUNCT dti-1406 104 11 f(3,35 f(3,35 ADJ dti-1406 104 12 ) ) PUNCT dti-1406 104 13     SPACE dti-1406 104 14 = = NOUN dti-1406 104 15     SPACE dti-1406 104 16 11.71 11.71 NUM dti-1406 104 17 , , PUNCT dti-1406 104 18 p p X dti-1406 104 19     SPACE dti-1406 104 20 , , PUNCT dti-1406 104 21     SPACE dti-1406 104 22 0.001 0.001 NUM dti-1406 104 23 ; ; PUNCT dti-1406 104 24 f(3,35 f(3,35 ADJ dti-1406 104 25 ) ) PUNCT dti-1406 104 26     SPACE dti-1406 105 1 = = NOUN dti-1406 105 2     SPACE dti-1406 105 3 7.41 7.41 NUM dti-1406 105 4 , , PUNCT dti-1406 105 5 p p X dti-1406 105 6     SPACE dti-1406 105 7 , , PUNCT dti-1406 105 8     SPACE dti-1406 105 9 0.001 0.001 NUM dti-1406 105 10 ; ; PUNCT dti-1406 105 11 and and CCONJ dti-1406 105 12 f(3,35 f(3,35 ADJ dti-1406 105 13 ) ) PUNCT dti-1406 105 14     SPACE dti-1406 106 1 = = NOUN dti-1406 106 2     SPACE dti-1406 106 3 10.24 10.24 NUM dti-1406 106 4 , , PUNCT dti-1406 106 5 p p X dti-1406 106 6     SPACE dti-1406 106 7 , , PUNCT dti-1406 106 8     SPACE dti-1406 106 9 0.001 0.001 NUM dti-1406 106 10 ; ; PUNCT dti-1406 106 11 respectively respectively ADV dti-1406 106 12 ; ; PUNCT dti-1406 106 13 fig fig NOUN dti-1406 106 14 . . PUNCT dti-1406 107 1 2a 2a NUM dti-1406 107 2 ] ] PUNCT dti-1406 107 3 . . PUNCT dti-1406 108 1 7 7 NUM dti-1406 108 2 - - SYM dti-1406 108 3 ni ni PROPN dti-1406 108 4 ( ( PUNCT dti-1406 108 5 15 15 NUM dti-1406 108 6     SPACE dti-1406 108 7 mg mg PROPN dti-1406 108 8 / / SYM dti-1406 108 9 kg kg NOUN dti-1406 108 10 ) ) PUNCT dti-1406 108 11 significantly significantly ADV dti-1406 108 12 increased increase VERB dti-1406 108 13 the the DET dti-1406 108 14 escape escape NOUN dti-1406 108 15 latency latency NOUN dti-1406 108 16 during during ADP dti-1406 108 17 the the DET dti-1406 108 18 first first ADJ dti-1406 108 19 , , PUNCT dti-1406 108 20 second second ADJ dti-1406 108 21 , , PUNCT dti-1406 108 22 third third ADJ dti-1406 108 23 , , PUNCT dti-1406 108 24 and and CCONJ dti-1406 108 25 fourth fourth ADJ dti-1406 108 26 sessions session NOUN dti-1406 108 27 ( ( PUNCT dti-1406 108 28 p p X dti-1406 108 29     SPACE dti-1406 108 30 = = NOUN dti-1406 108 31     SPACE dti-1406 108 32 0.01 0.01 NUM dti-1406 108 33 ; ; PUNCT dti-1406 109 1 p p X dti-1406 109 2     SPACE dti-1406 109 3 , , PUNCT dti-1406 109 4     SPACE dti-1406 109 5 0.01 0.01 NUM dti-1406 109 6 ; ; PUNCT dti-1406 109 7 p p X dti-1406 109 8     SPACE dti-1406 109 9 , , PUNCT dti-1406 109 10     SPACE dti-1406 109 11 0.01 0.01 NUM dti-1406 109 12 ; ; PUNCT dti-1406 109 13 and and CCONJ dti-1406 109 14 p p X dti-1406 109 15     SPACE dti-1406 109 16 , , PUNCT dti-1406 109 17     SPACE dti-1406 109 18 0.001 0.001 NUM dti-1406 109 19 , , PUNCT dti-1406 109 20 figure figure NOUN dti-1406 109 21 1 1 NUM dti-1406 109 22 . . PUNCT dti-1406 109 23 drug drug NOUN dti-1406 109 24 effects effect NOUN dti-1406 109 25 on on ADP dti-1406 109 26 ( ( PUNCT dti-1406 109 27 a a DET dti-1406 109 28 ) ) PUNCT dti-1406 109 29 transfer transfer NOUN dti-1406 109 30 latency latency NOUN dti-1406 109 31 1 1 NUM dti-1406 109 32 ( ( PUNCT dti-1406 109 33 tl-1 tl-1 NUM dti-1406 109 34 ) ) PUNCT dti-1406 109 35 and and CCONJ dti-1406 109 36 ( ( PUNCT dti-1406 109 37 b b NOUN dti-1406 109 38 ) ) PUNCT dti-1406 109 39 transfer transfer NOUN dti-1406 109 40 latency latency NOUN dti-1406 109 41 2 2 NUM dti-1406 109 42 ( ( PUNCT dti-1406 109 43 tl-2 tl-2 NUM dti-1406 109 44 ) ) PUNCT dti-1406 109 45 ( ( PUNCT dti-1406 109 46 n n NOUN dti-1406 109 47 = = SYM dti-1406 109 48 6 6 NUM dti-1406 109 49 ) ) PUNCT dti-1406 109 50 in in ADP dti-1406 109 51 the the DET dti-1406 109 52 mepm mepm NOUN dti-1406 109 53 test test NOUN dti-1406 109 54 in in ADP dti-1406 109 55 mice mouse NOUN dti-1406 109 56 . . PUNCT dti-1406 110 1 odq odq NOUN dti-1406 110 2 ( ( PUNCT dti-1406 110 3 3 3 NUM dti-1406 110 4 and and CCONJ dti-1406 110 5 10 10 NUM dti-1406 110 6 mg mg NUM dti-1406 110 7 / / SYM dti-1406 110 8 kg kg PROPN dti-1406 110 9 ) ) PUNCT dti-1406 110 10 , , PUNCT dti-1406 110 11 7 7 PROPN dti-1406 110 12 - - SYM dti-1406 110 13 ni ni NOUN dti-1406 110 14 ( ( PUNCT dti-1406 110 15 15 15 NUM dti-1406 110 16 mg mg PROPN dti-1406 110 17 / / SYM dti-1406 110 18 kg kg PROPN dti-1406 110 19 ) ) PUNCT dti-1406 110 20 , , PUNCT dti-1406 110 21 or or CCONJ dti-1406 110 22 l l NOUN dti-1406 110 23 - - NOUN dti-1406 110 24 arginine arginine NOUN dti-1406 110 25 ( ( PUNCT dti-1406 110 26 100 100 NUM dti-1406 110 27 mg mg NUM dti-1406 110 28 / / SYM dti-1406 110 29 kg kg PROPN dti-1406 110 30 ) ) PUNCT dti-1406 110 31 was be AUX dti-1406 110 32 administered administer VERB dti-1406 110 33 30 30 NUM dti-1406 110 34 , , PUNCT dti-1406 110 35 30 30 NUM dti-1406 110 36 , , PUNCT dti-1406 110 37 and and CCONJ dti-1406 110 38 60 60 NUM dti-1406 110 39 minutes minute NOUN dti-1406 110 40 , , PUNCT dti-1406 110 41 respectively respectively ADV dti-1406 110 42 , , PUNCT dti-1406 110 43 prior prior ADV dti-1406 110 44 to to ADP dti-1406 110 45 the the DET dti-1406 110 46 acquisition acquisition NOUN dti-1406 110 47 trial trial NOUN dti-1406 110 48 of of ADP dti-1406 110 49 the the DET dti-1406 110 50 mepm mepm NOUN dti-1406 110 51 test test NOUN dti-1406 110 52 . . PUNCT dti-1406 111 1 the the DET dti-1406 111 2 data datum NOUN dti-1406 111 3 are be AUX dti-1406 111 4 expressed express VERB dti-1406 111 5 as as ADP dti-1406 111 6 the the DET dti-1406 111 7 mean mean ADJ dti-1406 111 8 ± ± NUM dti-1406 111 9 sem sem NOUN dti-1406 111 10 values value NOUN dti-1406 111 11 of of ADP dti-1406 111 12 the the DET dti-1406 111 13 animals animal NOUN dti-1406 111 14 . . PUNCT dti-1406 112 1 * * PUNCT dti-1406 112 2 p p NOUN dti-1406 112 3 , , PUNCT dti-1406 112 4 0.05 0.05 NUM dti-1406 112 5 , , PUNCT dti-1406 112 6 * * PUNCT dti-1406 112 7 * * PUNCT dti-1406 112 8 p p X dti-1406 112 9 , , PUNCT dti-1406 112 10 0.001 0.001 NUM dti-1406 112 11 compared compare VERB dti-1406 112 12 with with ADP dti-1406 112 13 the the DET dti-1406 112 14 control control NOUN dti-1406 112 15 group group NOUN dti-1406 112 16 . . PUNCT dti-1406 113 1 # # SYM dti-1406 113 2 p p NOUN dti-1406 113 3 , , PUNCT dti-1406 113 4 0.001 0.001 NUM dti-1406 113 5 compared compare VERB dti-1406 113 6 with with ADP dti-1406 113 7 the the DET dti-1406 113 8 7 7 NUM dti-1406 113 9 - - PUNCT dti-1406 113 10 ni ni NOUN dti-1406 113 11 group group NOUN dti-1406 113 12 . . PUNCT dti-1406 114 1 http://www.la-press.com http://www.la-press.com X dti-1406 114 2 http://www.la-press.com/drug-target-insights-journal-j23 http://www.la-press.com/drug-target-insights-journal-j23 PROPN dti-1406 114 3 mutlu mutlu PROPN dti-1406 114 4 et et PROPN dti-1406 114 5 al al PROPN dti-1406 114 6 4 4 NUM dti-1406 114 7 drug drug NOUN dti-1406 114 8 target target NOUN dti-1406 114 9 insights insight NOUN dti-1406 114 10 2015:9 2015:9 NUM dti-1406 114 11 morris morris PROPN dti-1406 114 12 water water PROPN dti-1406 114 13 maze maze NOUN dti-1406 114 14 test test NOUN dti-1406 114 15 0 0 NUM dti-1406 114 16 5 5 NUM dti-1406 114 17 10 10 NUM dti-1406 114 18 15 15 NUM dti-1406 114 19 20 20 NUM dti-1406 114 20 25 25 NUM dti-1406 114 21 30 30 NUM dti-1406 114 22 35 35 NUM dti-1406 114 23 drugs drug NOUN dti-1406 114 24 ( ( PUNCT dti-1406 114 25 mg mg PROPN dti-1406 114 26 / / SYM dti-1406 114 27 kg kg NOUN dti-1406 114 28 ) ) PUNCT dti-1406 115 1 ti ti NOUN dti-1406 115 2 m m NOUN dti-1406 115 3 e e NOUN dti-1406 115 4 sp sp ADP dti-1406 115 5 en en ADP dti-1406 115 6 t t PROPN dti-1406 115 7 i i PRON dti-1406 116 1 n n PROPN dti-1406 116 2 es es VERB dti-1406 116 3 ca can AUX dti-1406 116 4 pe pe AUX dti-1406 116 5 pl pl VERB dti-1406 116 6 at at ADP dti-1406 116 7 fo fo ADP dti-1406 117 1 rm rm PROPN dti-1406 117 2 ’s ’s PART dti-1406 117 3 q q PROPN dti-1406 117 4 ua ua PROPN dti-1406 117 5 dr dr PROPN dti-1406 117 6 an an PROPN dti-1406 117 7 t t PROPN dti-1406 117 8 ( ( PUNCT dti-1406 117 9 s s X dti-1406 117 10 ) ) PUNCT dti-1406 117 11 es es NOUN dti-1406 117 12 ca can AUX dti-1406 117 13 pe pe VERB dti-1406 117 14 la la VERB dti-1406 117 15 te te PROPN dti-1406 117 16 nc nc PROPN dti-1406 117 17 y y PROPN dti-1406 117 18 ( ( PUNCT dti-1406 117 19 s s NOUN dti-1406 117 20 ) ) PUNCT dti-1406 117 21 180 180 NUM dti-1406 117 22 160 160 NUM dti-1406 117 23 140 140 NUM dti-1406 117 24 120 120 NUM dti-1406 117 25 100 100 NUM dti-1406 117 26 80 80 NUM dti-1406 117 27 60 60 NUM dti-1406 117 28 40 40 NUM dti-1406 117 29 20 20 NUM dti-1406 117 30 0 0 NUM dti-1406 117 31 fam fam NOUN dti-1406 117 32 ses se NOUN dti-1406 117 33 1st 1st PROPN dti-1406 117 34 ses se NOUN dti-1406 117 35 2nd 2nd ADJ dti-1406 117 36 ses se NOUN dti-1406 117 37 3rd 3rd PROPN dti-1406 117 38 ses se NOUN dti-1406 117 39 4th 4th ADJ dti-1406 117 40 ses se NOUN dti-1406 117 41 morris morris PROPN dti-1406 117 42 water water NOUN dti-1406 117 43 maze maze NOUN dti-1406 117 44 testa testa PROPN dti-1406 117 45 b b PROPN dti-1406 117 46 c c NOUN dti-1406 117 47 d d X dti-1406 117 48 control control NOUN dti-1406 117 49 odq odq NOUN dti-1406 117 50 3 3 NUM dti-1406 117 51 odq odq NOUN dti-1406 117 52 10 10 NUM dti-1406 117 53 7 7 NUM dti-1406 117 54 - - PUNCT dti-1406 117 55 ni ni PROPN dti-1406 117 56 ( ( PUNCT dti-1406 117 57 30 30 NUM dti-1406 117 58 ) ) PUNCT dti-1406 117 59 7 7 NUM dti-1406 117 60 - - PUNCT dti-1406 117 61 ni ni PROPN dti-1406 117 62 ( ( PUNCT dti-1406 117 63 30 30 NUM dti-1406 117 64 ) ) PUNCT dti-1406 118 1 + + CCONJ dti-1406 118 2 l l NOUN dti-1406 118 3 - - NOUN dti-1406 118 4 arg arg NOUN dti-1406 118 5 ( ( PUNCT dti-1406 118 6 100 100 NUM dti-1406 118 7 ) ) PUNCT dti-1406 118 8 sessions session NOUN dti-1406 118 9 morris morris PROPN dti-1406 118 10 water water PROPN dti-1406 118 11 maze maze NOUN dti-1406 118 12 test test NOUN dti-1406 118 13 morris morris PROPN dti-1406 118 14 water water PROPN dti-1406 118 15 maze maze NOUN dti-1406 118 16 test test NOUN dti-1406 118 17 0 0 NUM dti-1406 118 18 5 5 NUM dti-1406 118 19 10 10 NUM dti-1406 118 20 15 15 NUM dti-1406 118 21 20 20 NUM dti-1406 118 22 25 25 NUM dti-1406 118 23 30 30 NUM dti-1406 118 24 35 35 NUM dti-1406 118 25 drugs drug NOUN dti-1406 118 26 ( ( PUNCT dti-1406 118 27 mg mg PROPN dti-1406 118 28 / / SYM dti-1406 118 29 kg kg NOUN dti-1406 118 30 ) ) PUNCT dti-1406 118 31 drugs drug NOUN dti-1406 118 32 ( ( PUNCT dti-1406 118 33 mg mg PROPN dti-1406 118 34 / / SYM dti-1406 118 35 kg kg NOUN dti-1406 118 36 ) ) PUNCT dti-1406 118 37 m m PROPN dti-1406 118 38 ea ea NOUN dti-1406 118 39 n n ADP dti-1406 118 40 di di PROPN dti-1406 118 41 st st PROPN dti-1406 118 42 an an PROPN dti-1406 118 43 ce ce PROPN dti-1406 118 44 to to PART dti-1406 118 45 pl pl VERB dti-1406 118 46 at at ADP dti-1406 118 47 fo fo ADP dti-1406 118 48 rm rm PROPN dti-1406 118 49 ( ( PUNCT dti-1406 118 50 c c NOUN dti-1406 118 51 m m NOUN dti-1406 118 52 ) ) PUNCT dti-1406 118 53 control control NOUN dti-1406 118 54 odq odq NOUN dti-1406 118 55 3 3 NUM dti-1406 118 56 odq odq NOUN dti-1406 118 57 10 10 NUM dti-1406 118 58 7 7 NUM dti-1406 118 59 - - PUNCT dti-1406 118 60 ni ni PROPN dti-1406 118 61 ( ( PUNCT dti-1406 118 62 15 15 NUM dti-1406 118 63 ) ) PUNCT dti-1406 118 64 7 7 NUM dti-1406 118 65 - - PUNCT dti-1406 118 66 ni ni PROPN dti-1406 118 67 ( ( PUNCT dti-1406 118 68 15 15 NUM dti-1406 118 69 ) ) PUNCT dti-1406 118 70 + + CCONJ dti-1406 118 71 l l NOUN dti-1406 118 72 - - NOUN dti-1406 118 73 arg arg NOUN dti-1406 118 74 ( ( PUNCT dti-1406 118 75 100 100 NUM dti-1406 118 76 ) ) PUNCT dti-1406 118 77 # # NOUN dti-1406 118 78 14.5 14.5 NUM dti-1406 118 79 15 15 NUM dti-1406 118 80 15.5 15.5 NUM dti-1406 118 81 16 16 NUM dti-1406 118 82 16.5 16.5 NUM dti-1406 118 83 17 17 NUM dti-1406 118 84 17.5 17.5 NUM dti-1406 118 85 18 18 NUM dti-1406 118 86 18.5 18.5 NUM dti-1406 118 87 19 19 NUM dti-1406 118 88 19.5 19.5 NUM dti-1406 118 89 sp sp ADP dti-1406 118 90 ee ee PROPN dti-1406 118 91 d d PROPN dti-1406 118 92 ( ( PUNCT dti-1406 118 93 c c NOUN dti-1406 118 94 m m VERB dti-1406 118 95 /s /s PUNCT dti-1406 118 96 ) ) PUNCT dti-1406 119 1 * * PUNCT dti-1406 120 1 * * PUNCT dti-1406 121 1 * * PUNCT dti-1406 121 2 * * PUNCT dti-1406 121 3 * * PUNCT dti-1406 121 4 * * PUNCT dti-1406 121 5 * * PUNCT dti-1406 121 6 # # NOUN dti-1406 121 7 figure figure NOUN dti-1406 121 8 2 2 NUM dti-1406 121 9 . . PUNCT dti-1406 121 10 drug drug NOUN dti-1406 121 11 effects effect NOUN dti-1406 121 12 on on ADP dti-1406 121 13 ( ( PUNCT dti-1406 121 14 a a X dti-1406 121 15 ) ) PUNCT dti-1406 121 16 the the DET dti-1406 121 17 escape escape NOUN dti-1406 121 18 latency latency NOUN dti-1406 121 19 in in ADP dti-1406 121 20 five five NUM dti-1406 121 21 acquisition acquisition NOUN dti-1406 121 22 sessions session NOUN dti-1406 121 23 of of ADP dti-1406 121 24 the the DET dti-1406 121 25 mwm mwm NOUN dti-1406 121 26 test test NOUN dti-1406 121 27 , , PUNCT dti-1406 121 28 ( ( PUNCT dti-1406 121 29 b b X dti-1406 121 30 ) ) PUNCT dti-1406 121 31 the the DET dti-1406 121 32 time time NOUN dti-1406 121 33 spent spend VERB dti-1406 121 34 in in ADP dti-1406 121 35 the the DET dti-1406 121 36 escape escape NOUN dti-1406 121 37 platform platform NOUN dti-1406 121 38 ’s ’s PART dti-1406 121 39 quadrant quadrant NOUN dti-1406 121 40 in in ADP dti-1406 121 41 the the DET dti-1406 121 42 probe probe NOUN dti-1406 121 43 trial trial NOUN dti-1406 121 44 ( ( PUNCT dti-1406 121 45 60 60 NUM dti-1406 121 46 seconds second NOUN dti-1406 121 47 ) ) PUNCT dti-1406 121 48 in in ADP dti-1406 121 49 the the DET dti-1406 121 50 mwm mwm NOUN dti-1406 121 51 test test NOUN dti-1406 121 52 , , PUNCT dti-1406 121 53 ( ( PUNCT dti-1406 121 54 c c X dti-1406 121 55 ) ) PUNCT dti-1406 121 56 the the DET dti-1406 121 57 mean mean ADJ dti-1406 121 58 distance distance NOUN dti-1406 121 59 to to ADP dti-1406 121 60 the the DET dti-1406 121 61 platform platform NOUN dti-1406 121 62 in in ADP dti-1406 121 63 the the DET dti-1406 121 64 probe probe NOUN dti-1406 121 65 trial trial NOUN dti-1406 121 66 ( ( PUNCT dti-1406 121 67 60 60 NUM dti-1406 121 68 seconds second NOUN dti-1406 121 69 ) ) PUNCT dti-1406 121 70 of of ADP dti-1406 121 71 the the DET dti-1406 121 72 mwm mwm NOUN dti-1406 121 73 test test NOUN dti-1406 121 74 , , PUNCT dti-1406 121 75 and and CCONJ dti-1406 121 76 ( ( PUNCT dti-1406 121 77 d d X dti-1406 121 78 ) ) PUNCT dti-1406 121 79 the the DET dti-1406 121 80 swimming swimming NOUN dti-1406 121 81 speed speed NOUN dti-1406 121 82 in in ADP dti-1406 121 83 the the DET dti-1406 121 84 probe probe NOUN dti-1406 121 85 trial trial NOUN dti-1406 121 86 ( ( PUNCT dti-1406 121 87 60 60 NUM dti-1406 121 88 seconds second NOUN dti-1406 121 89 ) ) PUNCT dti-1406 121 90 of of ADP dti-1406 121 91 the the DET dti-1406 121 92 mwm mwm NOUN dti-1406 121 93 test test NOUN dti-1406 121 94 . . PUNCT dti-1406 122 1 odq odq NOUN dti-1406 122 2 ( ( PUNCT dti-1406 122 3 3 3 NUM dti-1406 122 4 and and CCONJ dti-1406 122 5 10 10 NUM dti-1406 122 6 mg mg NUM dti-1406 122 7 / / SYM dti-1406 122 8 kg kg PROPN dti-1406 122 9 ) ) PUNCT dti-1406 122 10 , , PUNCT dti-1406 122 11 7ni 7ni ADJ dti-1406 122 12 ( ( PUNCT dti-1406 122 13 15 15 NUM dti-1406 122 14 mg mg PROPN dti-1406 122 15 / / SYM dti-1406 122 16 kg kg PROPN dti-1406 122 17 ) ) PUNCT dti-1406 122 18 , , PUNCT dti-1406 122 19 or or CCONJ dti-1406 122 20 l l NOUN dti-1406 122 21 - - NOUN dti-1406 122 22 arg arg NOUN dti-1406 122 23 ( ( PUNCT dti-1406 122 24 100 100 NUM dti-1406 122 25 mg mg NUM dti-1406 122 26 / / SYM dti-1406 122 27 kg kg PROPN dti-1406 122 28 ) ) PUNCT dti-1406 122 29 was be AUX dti-1406 122 30 administered administer VERB dti-1406 122 31 daily daily ADV dti-1406 122 32 30 30 NUM dti-1406 122 33 , , PUNCT dti-1406 122 34 30 30 NUM dti-1406 122 35 , , PUNCT dti-1406 122 36 and and CCONJ dti-1406 122 37 60 60 NUM dti-1406 122 38 minutes minute NOUN dti-1406 122 39 , , PUNCT dti-1406 122 40 respectively respectively ADV dti-1406 122 41 , , PUNCT dti-1406 122 42 prior prior ADV dti-1406 122 43 to to ADP dti-1406 122 44 the the DET dti-1406 122 45 first first ADJ dti-1406 122 46 trial trial NOUN dti-1406 122 47 of of ADP dti-1406 122 48 the the DET dti-1406 122 49 day day NOUN dti-1406 122 50 for for ADP dti-1406 122 51 6 6 NUM dti-1406 122 52 days day NOUN dti-1406 122 53 . . PUNCT dti-1406 123 1 results result NOUN dti-1406 123 2 are be AUX dti-1406 123 3 expressed express VERB dti-1406 123 4 as as ADP dti-1406 123 5 the the DET dti-1406 123 6 mean mean PROPN dti-1406 123 7 ± ± NUM dti-1406 123 8 sem sem NOUN dti-1406 123 9 . . PUNCT dti-1406 124 1 n n NOUN dti-1406 125 1 = = SYM dti-1406 125 2 7 7 NUM dti-1406 125 3 per per ADP dti-1406 125 4 group group NOUN dti-1406 125 5 . . PUNCT dti-1406 126 1 * * PUNCT dti-1406 126 2 p p NOUN dti-1406 126 3 , , PUNCT dti-1406 126 4 0.05 0.05 NUM dti-1406 126 5 , , PUNCT dti-1406 126 6 * * PUNCT dti-1406 126 7 * * PUNCT dti-1406 126 8 p p X dti-1406 126 9 , , PUNCT dti-1406 126 10 0.01 0.01 NUM dti-1406 126 11 , , PUNCT dti-1406 126 12 * * PUNCT dti-1406 126 13 * * PUNCT dti-1406 126 14 * * PUNCT dti-1406 126 15 p p X dti-1406 126 16 , , PUNCT dti-1406 126 17 0.001 0.001 NUM dti-1406 126 18 compared compare VERB dti-1406 126 19 with with ADP dti-1406 126 20 the the DET dti-1406 126 21 control control NOUN dti-1406 126 22 group group NOUN dti-1406 126 23 ; ; PUNCT dti-1406 126 24 # # SYM dti-1406 126 25 p p NOUN dti-1406 126 26 , , PUNCT dti-1406 126 27 0.001 0.001 NUM dti-1406 126 28 compared compare VERB dti-1406 126 29 with with ADP dti-1406 126 30 the the DET dti-1406 126 31 7 7 NUM dti-1406 126 32 - - PUNCT dti-1406 126 33 ni ni NOUN dti-1406 126 34 group group NOUN dti-1406 126 35 . . PUNCT dti-1406 127 1 http://www.la-press.com http://www.la-press.com X dti-1406 128 1 http://www.la-press.com/drug-target-insights-journal-j23 http://www.la-press.com/drug-target-insights-journal-j23 PROPN dti-1406 128 2 7 7 NUM dti-1406 128 3 - - SYM dti-1406 128 4 ni ni NOUN dti-1406 128 5 and and CCONJ dti-1406 128 6 odq odq NOUN dti-1406 128 7 disturbs disturb VERB dti-1406 128 8 memory memory NOUN dti-1406 128 9 in in ADP dti-1406 128 10 the the DET dti-1406 128 11 elevated elevated ADJ dti-1406 128 12 plus plus CCONJ dti-1406 128 13 maze maze ADJ dti-1406 128 14 5drug 5drug NUM dti-1406 128 15 target target NOUN dti-1406 128 16 insights insight NOUN dti-1406 128 17 2015:9 2015:9 NUM dti-1406 128 18 respectively respectively ADV dti-1406 128 19 ) ) PUNCT dti-1406 128 20 , , PUNCT dti-1406 128 21 whereas whereas SCONJ dti-1406 128 22 odq odq PROPN dti-1406 128 23 10 10 NUM dti-1406 128 24     SPACE dti-1406 128 25 mg mg PROPN dti-1406 128 26 / / SYM dti-1406 128 27 kg kg PROPN dti-1406 128 28 significantly significantly ADV dti-1406 128 29 increased increase VERB dti-1406 128 30 the the DET dti-1406 128 31 escape escape NOUN dti-1406 128 32 latency latency NOUN dti-1406 128 33 during during ADP dti-1406 128 34 the the DET dti-1406 128 35 second second ADJ dti-1406 128 36 , , PUNCT dti-1406 128 37 third third ADJ dti-1406 128 38 , , PUNCT dti-1406 128 39 and and CCONJ dti-1406 128 40 fourth fourth ADJ dti-1406 128 41 sessions session NOUN dti-1406 128 42 ( ( PUNCT dti-1406 128 43 p p X dti-1406 128 44     SPACE dti-1406 128 45 , , PUNCT dti-1406 128 46     SPACE dti-1406 128 47 0.01 0.01 NUM dti-1406 128 48 ; ; PUNCT dti-1406 128 49 p p X dti-1406 128 50     SPACE dti-1406 128 51 , , PUNCT dti-1406 128 52     SPACE dti-1406 128 53 0.05 0.05 NUM dti-1406 128 54 ; ; PUNCT dti-1406 128 55 and and CCONJ dti-1406 128 56 p p X dti-1406 128 57     SPACE dti-1406 128 58 , , PUNCT dti-1406 128 59     SPACE dti-1406 128 60 0.05 0.05 NUM dti-1406 128 61 , , PUNCT dti-1406 128 62 respectively respectively ADV dti-1406 128 63 ) ) PUNCT dti-1406 128 64 compared compare VERB dti-1406 128 65 with with ADP dti-1406 128 66 the the DET dti-1406 128 67 control control NOUN dti-1406 128 68 in in ADP dti-1406 128 69 naive naive ADJ dti-1406 128 70 mice mouse NOUN dti-1406 128 71 . . PUNCT dti-1406 129 1 l l NOUN dti-1406 129 2 - - NOUN dti-1406 129 3 arginine arginine NOUN dti-1406 129 4 ( ( PUNCT dti-1406 129 5 100 100 NUM dti-1406 129 6     SPACE dti-1406 129 7 mg mg PROPN dti-1406 129 8 / / SYM dti-1406 129 9 kg kg NOUN dti-1406 129 10 ) ) PUNCT dti-1406 129 11 significantly significantly ADV dti-1406 129 12 reversed reverse VERB dti-1406 129 13 the the DET dti-1406 129 14 effects effect NOUN dti-1406 129 15 of of ADP dti-1406 129 16 7 7 NUM dti-1406 129 17 - - PUNCT dti-1406 129 18 ni ni NOUN dti-1406 129 19 ( ( PUNCT dti-1406 129 20 15 15 NUM dti-1406 129 21     SPACE dti-1406 129 22 mg mg PROPN dti-1406 129 23 / / SYM dti-1406 129 24 kg kg NOUN dti-1406 129 25 ) ) PUNCT dti-1406 129 26 on on ADP dti-1406 129 27 the the DET dti-1406 129 28 escape escape NOUN dti-1406 129 29 latency latency NOUN dti-1406 129 30 in in ADP dti-1406 129 31 the the DET dti-1406 129 32 first first ADJ dti-1406 129 33 , , PUNCT dti-1406 129 34 second second ADJ dti-1406 129 35 , , PUNCT dti-1406 129 36 third third ADJ dti-1406 129 37 , , PUNCT dti-1406 129 38 and and CCONJ dti-1406 129 39 fourth fourth ADJ dti-1406 129 40 sessions session NOUN dti-1406 129 41 [ [ X dti-1406 129 42 f(1,35 f(1,35 NOUN dti-1406 129 43 ) ) PUNCT dti-1406 129 44     SPACE dti-1406 130 1 = = NOUN dti-1406 130 2     SPACE dti-1406 130 3 13.49 13.49 NUM dti-1406 130 4 ; ; PUNCT dti-1406 130 5 p p X dti-1406 130 6     SPACE dti-1406 130 7 , , PUNCT dti-1406 130 8     SPACE dti-1406 130 9 0.001 0.001 NUM dti-1406 130 10 ; ; PUNCT dti-1406 130 11 f(1,35 f(1,35 NOUN dti-1406 130 12 ) ) PUNCT dti-1406 130 13     SPACE dti-1406 131 1 = = NOUN dti-1406 131 2     SPACE dti-1406 131 3 23.29 23.29 NUM dti-1406 131 4 ; ; PUNCT dti-1406 131 5 p p X dti-1406 131 6     SPACE dti-1406 131 7 , , PUNCT dti-1406 131 8     SPACE dti-1406 131 9 0.001 0.001 NUM dti-1406 131 10 ; ; PUNCT dti-1406 131 11 f(1,35 f(1,35 NOUN dti-1406 131 12 ) ) PUNCT dti-1406 131 13     SPACE dti-1406 132 1 = = NOUN dti-1406 132 2     SPACE dti-1406 132 3 15.23 15.23 NUM dti-1406 132 4 ; ; PUNCT dti-1406 132 5 p p X dti-1406 132 6     SPACE dti-1406 132 7 , , PUNCT dti-1406 132 8     SPACE dti-1406 132 9 0.001 0.001 NUM dti-1406 132 10 ; ; PUNCT dti-1406 132 11 and and CCONJ dti-1406 132 12 f(1,35 f(1,35 ADJ dti-1406 132 13 ) ) PUNCT dti-1406 132 14     SPACE dti-1406 133 1 = = NOUN dti-1406 133 2     SPACE dti-1406 133 3 29.19 29.19 NUM dti-1406 133 4 ; ; PUNCT dti-1406 133 5 p p X dti-1406 133 6     SPACE dti-1406 133 7 , , PUNCT dti-1406 133 8     SPACE dti-1406 133 9 0.001 0.001 NUM dti-1406 133 10 , , PUNCT dti-1406 133 11 respectively respectively ADV dti-1406 133 12 ; ; PUNCT dti-1406 133 13 fig fig NOUN dti-1406 133 14 . . PUNCT dti-1406 134 1 2a 2a NUM dti-1406 134 2 ] ] PUNCT dti-1406 134 3 . . PUNCT dti-1406 135 1 a a DET dti-1406 135 2 significant significant ADJ dti-1406 135 3 difference difference NOUN dti-1406 135 4 was be AUX dti-1406 135 5 noted note VERB dti-1406 135 6 between between ADP dti-1406 135 7 all all DET dti-1406 135 8 drug drug NOUN dti-1406 135 9 groups group NOUN dti-1406 135 10 in in ADP dti-1406 135 11 the the DET dti-1406 135 12 time time NOUN dti-1406 135 13 spent spend VERB dti-1406 135 14 in in ADP dti-1406 135 15 the the DET dti-1406 135 16 target target NOUN dti-1406 135 17 quadrant quadrant NOUN dti-1406 136 1 [ [ X dti-1406 136 2 f(3,35 f(3,35 ADJ dti-1406 136 3 ) ) PUNCT dti-1406 136 4     SPACE dti-1406 137 1 = = NOUN dti-1406 137 2     SPACE dti-1406 137 3 6.04 6.04 NUM dti-1406 137 4 ; ; PUNCT dti-1406 137 5 p p X dti-1406 137 6     SPACE dti-1406 137 7 = = NOUN dti-1406 137 8     SPACE dti-1406 137 9 0.002 0.002 NUM dti-1406 137 10 ; ; PUNCT dti-1406 137 11 fig fig NOUN dti-1406 137 12 . . PUNCT dti-1406 137 13 2b 2b NUM dti-1406 137 14 ] ] PUNCT dti-1406 137 15 . . PUNCT dti-1406 138 1 7 7 NUM dti-1406 138 2 - - SYM dti-1406 138 3 ni ni PROPN dti-1406 138 4 ( ( PUNCT dti-1406 138 5 15 15 NUM dti-1406 138 6     SPACE dti-1406 138 7 mg mg PROPN dti-1406 138 8 / / SYM dti-1406 138 9 kg kg PROPN dti-1406 138 10 ) ) PUNCT dti-1406 138 11 and and CCONJ dti-1406 138 12 odq odq NOUN dti-1406 138 13 ( ( PUNCT dti-1406 138 14 10 10 NUM dti-1406 138 15     SPACE dti-1406 138 16 mg mg PROPN dti-1406 138 17 / / SYM dti-1406 138 18 kg kg NOUN dti-1406 138 19 ) ) PUNCT dti-1406 138 20 significantly significantly ADV dti-1406 138 21 decreased decrease VERB dti-1406 138 22 the the DET dti-1406 138 23 time time NOUN dti-1406 138 24 spent spend VERB dti-1406 138 25 in in ADP dti-1406 138 26 the the DET dti-1406 138 27 escape escape NOUN dti-1406 138 28 platform platform NOUN dti-1406 138 29 ’s ’s PART dti-1406 138 30 quadrant quadrant NOUN dti-1406 138 31 ( ( PUNCT dti-1406 138 32 p p X dti-1406 138 33     SPACE dti-1406 138 34 , , PUNCT dti-1406 138 35     SPACE dti-1406 138 36 0.01 0.01 NUM dti-1406 138 37 and and CCONJ dti-1406 138 38 p p X dti-1406 138 39     SPACE dti-1406 138 40 , , PUNCT dti-1406 138 41     SPACE dti-1406 138 42 0.05 0.05 NUM dti-1406 138 43 , , PUNCT dti-1406 138 44 respectively respectively ADV dti-1406 138 45 ) ) PUNCT dti-1406 138 46 . . PUNCT dti-1406 139 1 l l X dti-1406 139 2 - - NOUN dti-1406 139 3 arg arg NOUN dti-1406 139 4 ( ( PUNCT dti-1406 139 5 100 100 NUM dti-1406 139 6     SPACE dti-1406 139 7 mg mg PROPN dti-1406 139 8 / / SYM dti-1406 139 9 kg kg PROPN dti-1406 139 10 ) ) PUNCT dti-1406 139 11 combined combine VERB dti-1406 139 12 with with ADP dti-1406 139 13 7 7 PROPN dti-1406 139 14 - - PUNCT dti-1406 139 15 ni ni NOUN dti-1406 139 16 significantly significantly ADV dti-1406 139 17 increased increase VERB dti-1406 139 18 the the DET dti-1406 139 19 decrease decrease NOUN dti-1406 139 20 in in ADP dti-1406 139 21 the the DET dti-1406 139 22 time time NOUN dti-1406 139 23 spent spend VERB dti-1406 139 24 in in ADP dti-1406 139 25 the the DET dti-1406 139 26 escape escape NOUN dti-1406 139 27 platform platform NOUN dti-1406 139 28 ’s ’s PART dti-1406 139 29 quadrant quadrant NOUN dti-1406 139 30 in in ADP dti-1406 139 31 the the DET dti-1406 139 32 7 7 NUM dti-1406 139 33 - - PUNCT dti-1406 139 34 ni ni ADJ dti-1406 139 35 only only ADJ dti-1406 139 36 group group NOUN dti-1406 139 37 [ [ X dti-1406 139 38 f(1,35 f(1,35 NOUN dti-1406 139 39 ) ) PUNCT dti-1406 139 40     SPACE dti-1406 140 1 = = NOUN dti-1406 140 2     SPACE dti-1406 140 3 12.06 12.06 NUM dti-1406 140 4 ; ; PUNCT dti-1406 140 5 p p X dti-1406 140 6     SPACE dti-1406 140 7 = = NOUN dti-1406 140 8     SPACE dti-1406 140 9 0.002 0.002 NUM dti-1406 140 10 ] ] PUNCT dti-1406 140 11 . . PUNCT dti-1406 141 1 the the DET dti-1406 141 2 mean mean ADJ dti-1406 141 3 distance distance NOUN dti-1406 141 4 traveled travel VERB dti-1406 141 5 by by ADP dti-1406 141 6 the the DET dti-1406 141 7 mice mouse NOUN dti-1406 141 8 to to ADP dti-1406 141 9 the the DET dti-1406 141 10 platform platform NOUN dti-1406 141 11 in in ADP dti-1406 141 12 the the DET dti-1406 141 13 probe probe NOUN dti-1406 141 14 trial trial NOUN dti-1406 141 15 of of ADP dti-1406 141 16 the the DET dti-1406 141 17 mwm mwm NOUN dti-1406 141 18 test test NOUN dti-1406 141 19 was be AUX dti-1406 141 20 significantly significantly ADV dti-1406 141 21 different different ADJ dti-1406 141 22 between between ADP dti-1406 141 23 the the DET dti-1406 141 24 drug drug NOUN dti-1406 141 25 groups group NOUN dti-1406 141 26 [ [ X dti-1406 141 27 f(3,35 f(3,35 ADJ dti-1406 141 28 ) ) PUNCT dti-1406 141 29     SPACE dti-1406 142 1 = = NOUN dti-1406 142 2     SPACE dti-1406 142 3 6.94 6.94 NUM dti-1406 142 4 ; ; PUNCT dti-1406 142 5 p p X dti-1406 142 6     SPACE dti-1406 142 7 = = NOUN dti-1406 142 8     SPACE dti-1406 142 9 0.001 0.001 NUM dti-1406 142 10 ; ; PUNCT dti-1406 142 11 fig fig NOUN dti-1406 142 12 . . PUNCT dti-1406 143 1 2c 2c NOUN dti-1406 143 2 ] ] PUNCT dti-1406 143 3 . . PUNCT dti-1406 144 1 7 7 NUM dti-1406 144 2 - - SYM dti-1406 144 3 ni ni PROPN dti-1406 144 4 15 15 NUM dti-1406 144 5     SPACE dti-1406 144 6 mg mg PROPN dti-1406 144 7 / / SYM dti-1406 144 8 kg kg PROPN dti-1406 144 9 and and CCONJ dti-1406 144 10 odq odq PROPN dti-1406 144 11 ( ( PUNCT dti-1406 144 12 10 10 NUM dti-1406 144 13     SPACE dti-1406 144 14 mg mg PROPN dti-1406 144 15 / / SYM dti-1406 144 16 kg kg NOUN dti-1406 144 17 ) ) PUNCT dti-1406 144 18 significantly significantly ADV dti-1406 144 19 increased increase VERB dti-1406 144 20 the the DET dti-1406 144 21 mean mean ADJ dti-1406 144 22 distance distance NOUN dti-1406 144 23 traveled travel VERB dti-1406 144 24 to to ADP dti-1406 144 25 the the DET dti-1406 144 26 platform platform NOUN dti-1406 144 27 ( ( PUNCT dti-1406 144 28 p p X dti-1406 144 29     SPACE dti-1406 144 30 , , PUNCT dti-1406 144 31     SPACE dti-1406 144 32 0.01 0.01 NUM dti-1406 144 33 ) ) PUNCT dti-1406 144 34 . . PUNCT dti-1406 145 1 l l X dti-1406 145 2 - - NOUN dti-1406 145 3 arg arg NOUN dti-1406 145 4 combined combine VERB dti-1406 145 5 with with ADP dti-1406 145 6 7 7 PROPN dti-1406 145 7 - - PUNCT dti-1406 145 8 ni ni NOUN dti-1406 145 9 significantly significantly ADV dti-1406 145 10 reversed reverse VERB dti-1406 145 11 the the DET dti-1406 145 12 effects effect NOUN dti-1406 145 13 of of ADP dti-1406 145 14 7 7 NUM dti-1406 145 15 - - PUNCT dti-1406 145 16 ni ni NOUN dti-1406 145 17 15 15 NUM dti-1406 145 18     SPACE dti-1406 145 19 mg mg PROPN dti-1406 145 20 / / SYM dti-1406 145 21 kg kg X dti-1406 146 1 [ [ X dti-1406 146 2 f(1,35 f(1,35 NOUN dti-1406 146 3 ) ) PUNCT dti-1406 146 4     SPACE dti-1406 146 5 = = NOUN dti-1406 146 6     SPACE dti-1406 146 7 12.06 12.06 NUM dti-1406 146 8 ; ; PUNCT dti-1406 146 9 p p X dti-1406 146 10     SPACE dti-1406 146 11 = = NOUN dti-1406 146 12     SPACE dti-1406 146 13 0.002 0.002 NUM dti-1406 146 14 ; ; PUNCT dti-1406 146 15 fig fig NOUN dti-1406 146 16 . . PUNCT dti-1406 147 1 2c 2c NOUN dti-1406 147 2 ] ] PUNCT dti-1406 147 3 . . PUNCT dti-1406 148 1 the the DET dti-1406 148 2 treatment treatment NOUN dti-1406 148 3 groups group NOUN dti-1406 148 4 were be AUX dti-1406 148 5 not not PART dti-1406 148 6 significantly significantly ADV dti-1406 148 7 different different ADJ dti-1406 148 8 in in ADP dti-1406 148 9 swimming swimming NOUN dti-1406 148 10 speed speed NOUN dti-1406 148 11 [ [ X dti-1406 148 12 f(3,35 f(3,35 ADJ dti-1406 148 13 ) ) PUNCT dti-1406 148 14 = = SYM dti-1406 148 15 0.06 0.06 NUM dti-1406 148 16 ; ; PUNCT dti-1406 148 17 p p X dti-1406 148 18 = = SYM dti-1406 148 19 0.97 0.97 NUM dti-1406 148 20 ; ; PUNCT dti-1406 148 21 fig fig NOUN dti-1406 148 22 . . PUNCT dti-1406 149 1 2d 2d NOUN dti-1406 149 2 ] ] PUNCT dti-1406 149 3 , , PUNCT dti-1406 149 4 and and CCONJ dti-1406 149 5 the the DET dti-1406 149 6 combination combination NOUN dti-1406 149 7 had have VERB dti-1406 149 8 no no DET dti-1406 149 9 effect effect NOUN dti-1406 149 10 on on ADP dti-1406 149 11 the the DET dti-1406 149 12 speed speed NOUN dti-1406 149 13 of of ADP dti-1406 149 14 the the DET dti-1406 149 15 animals animal NOUN dti-1406 149 16 in in ADP dti-1406 149 17 the the DET dti-1406 149 18 probe probe NOUN dti-1406 149 19 trial trial NOUN dti-1406 149 20 of of ADP dti-1406 149 21 the the DET dti-1406 149 22 mwm mwm NOUN dti-1406 149 23 test test NOUN dti-1406 149 24 [ [ X dti-1406 149 25 f(1 f(1 PROPN dti-1406 149 26 , , PUNCT dti-1406 149 27 35 35 NUM dti-1406 149 28 ) ) PUNCT dti-1406 149 29     SPACE dti-1406 150 1 = = NOUN dti-1406 150 2     SPACE dti-1406 150 3 0.02 0.02 NUM dti-1406 150 4 ; ; PUNCT dti-1406 150 5 p p X dti-1406 150 6     SPACE dti-1406 150 7 = = NOUN dti-1406 150 8     SPACE dti-1406 150 9 0.86 0.86 NUM dti-1406 150 10 ; ; PUNCT dti-1406 150 11 fig fig NOUN dti-1406 150 12 . . PUNCT dti-1406 151 1 2d 2d NOUN dti-1406 151 2 ] ] PUNCT dti-1406 151 3 . . PUNCT dti-1406 152 1 effects effect NOUN dti-1406 152 2 of of ADP dti-1406 152 3 7 7 NUM dti-1406 152 4 - - PUNCT dti-1406 152 5 ni ni PROPN dti-1406 152 6 , , PUNCT dti-1406 152 7 odq odq NOUN dti-1406 152 8 , , PUNCT dti-1406 152 9 and and CCONJ dti-1406 152 10 7 7 NUM dti-1406 152 11 - - PUNCT dti-1406 152 12 ni ni PROPN dti-1406 152 13 ± ± PROPN dti-1406 152 14 l l NOUN dti-1406 152 15 - - NOUN dti-1406 152 16 arginine arginine NOUN dti-1406 152 17 on on ADP dti-1406 152 18 learning learning NOUN dti-1406 152 19 and and CCONJ dti-1406 152 20 memory memory NOUN dti-1406 152 21 in in ADP dti-1406 152 22 the the DET dti-1406 152 23 ram ram NOUN dti-1406 152 24 test test NOUN dti-1406 152 25 . . PUNCT dti-1406 153 1 in in ADP dti-1406 153 2 the the DET dti-1406 153 3 evaluation evaluation NOUN dti-1406 153 4 of of ADP dti-1406 153 5 the the DET dti-1406 153 6 effects effect NOUN dti-1406 153 7 of of ADP dti-1406 153 8 acute acute ADJ dti-1406 153 9 treatment treatment NOUN dti-1406 153 10 with with ADP dti-1406 153 11 7 7 NUM dti-1406 153 12 - - PUNCT dti-1406 153 13 ni ni NOUN dti-1406 153 14 ( ( PUNCT dti-1406 153 15 15 15 NUM dti-1406 153 16     SPACE dti-1406 153 17 mg mg PROPN dti-1406 153 18 / / SYM dti-1406 153 19 kg kg PROPN dti-1406 153 20 ) ) PUNCT dti-1406 153 21 and and CCONJ dti-1406 153 22 odq odq NOUN dti-1406 153 23 ( ( PUNCT dti-1406 153 24 3 3 NUM dti-1406 153 25 and and CCONJ dti-1406 153 26 10 10 NUM dti-1406 153 27     SPACE dti-1406 153 28 mg mg PROPN dti-1406 153 29 / / SYM dti-1406 153 30 kg kg NOUN dti-1406 153 31 ) ) PUNCT dti-1406 153 32 administered administer VERB dti-1406 153 33 30 30 NUM dti-1406 153 34     SPACE dti-1406 153 35 minutes minute NOUN dti-1406 153 36 prior prior ADV dti-1406 153 37 to to ADP dti-1406 153 38 the the DET dti-1406 153 39 retention retention NOUN dti-1406 153 40 trial trial NOUN dti-1406 153 41 on on ADP dti-1406 153 42 the the DET dti-1406 153 43 number number NOUN dti-1406 153 44 of of ADP dti-1406 153 45 errors error NOUN dti-1406 153 46 in in ADP dti-1406 153 47 the the DET dti-1406 153 48 ram ram NOUN dti-1406 153 49 test test NOUN dti-1406 153 50 , , PUNCT dti-1406 153 51 a a DET dti-1406 153 52 significant significant ADJ dti-1406 153 53 difference difference NOUN dti-1406 153 54 between between ADP dti-1406 153 55 the the DET dti-1406 153 56 groups group NOUN dti-1406 153 57 was be AUX dti-1406 153 58 identified identify VERB dti-1406 153 59 [ [ X dti-1406 153 60 f(3,29 f(3,29 NOUN dti-1406 153 61 ) ) PUNCT dti-1406 153 62     SPACE dti-1406 154 1 = = NOUN dti-1406 154 2     SPACE dti-1406 154 3 19.08 19.08 NUM dti-1406 154 4 ; ; PUNCT dti-1406 154 5 p p X dti-1406 154 6     SPACE dti-1406 154 7 , , PUNCT dti-1406 154 8     SPACE dti-1406 154 9 0.001 0.001 NUM dti-1406 154 10 ] ] PUNCT dti-1406 154 11 . . PUNCT dti-1406 155 1 7 7 NUM dti-1406 155 2 - - SYM dti-1406 155 3 ni ni PROPN dti-1406 155 4 ( ( PUNCT dti-1406 155 5 15 15 NUM dti-1406 155 6     SPACE dti-1406 155 7 mg mg PROPN dti-1406 155 8 / / SYM dti-1406 155 9 kg kg PROPN dti-1406 155 10 ) ) PUNCT dti-1406 155 11 and and CCONJ dti-1406 155 12 odq odq NOUN dti-1406 155 13 ( ( PUNCT dti-1406 155 14 3 3 NUM dti-1406 155 15 and and CCONJ dti-1406 155 16 10 10 NUM dti-1406 155 17     SPACE dti-1406 155 18 mg mg PROPN dti-1406 155 19 / / SYM dti-1406 155 20 kg kg NOUN dti-1406 155 21 ) ) PUNCT dti-1406 155 22 significantly significantly ADV dti-1406 155 23 enhanced enhance VERB dti-1406 155 24 the the DET dti-1406 155 25 number number NOUN dti-1406 155 26 of of ADP dti-1406 155 27 working work VERB dti-1406 155 28 memory memory NOUN dti-1406 155 29 errors error NOUN dti-1406 155 30 in in ADP dti-1406 155 31 the the DET dti-1406 155 32 ram ram NOUN dti-1406 155 33 test test NOUN dti-1406 155 34 in in ADP dti-1406 155 35 mice mouse NOUN dti-1406 155 36 ( ( PUNCT dti-1406 155 37 p p X dti-1406 155 38     SPACE dti-1406 155 39 , , PUNCT dti-1406 155 40     SPACE dti-1406 155 41 0.001 0.001 NUM dti-1406 155 42 ) ) PUNCT dti-1406 155 43 . . PUNCT dti-1406 156 1 l l NOUN dti-1406 156 2 - - NOUN dti-1406 156 3 arg arg NOUN dti-1406 156 4 ( ( PUNCT dti-1406 156 5 100 100 NUM dti-1406 156 6     SPACE dti-1406 156 7 mg mg PROPN dti-1406 156 8 / / SYM dti-1406 156 9 kg kg NOUN dti-1406 156 10 ) ) PUNCT dti-1406 156 11 significantly significantly ADV dti-1406 156 12 decreased decrease VERB dti-1406 156 13 the the DET dti-1406 156 14 number number NOUN dti-1406 156 15 of of ADP dti-1406 156 16 working work VERB dti-1406 156 17 memory memory NOUN dti-1406 156 18 errors error NOUN dti-1406 156 19 in in ADP dti-1406 156 20 the the DET dti-1406 156 21 7 7 NUM dti-1406 156 22 - - PUNCT dti-1406 156 23 ni ni NOUN dti-1406 156 24 - - PUNCT dti-1406 156 25 treated treat VERB dti-1406 156 26 mice mouse NOUN dti-1406 156 27 [ [ X dti-1406 156 28 f(1,29 f(1,29 X dti-1406 156 29 ) ) PUNCT dti-1406 156 30     SPACE dti-1406 157 1 = = NOUN dti-1406 157 2     SPACE dti-1406 157 3 33.86 33.86 NUM dti-1406 157 4 ; ; PUNCT dti-1406 157 5 p p X dti-1406 157 6     SPACE dti-1406 157 7 , , PUNCT dti-1406 157 8     SPACE dti-1406 157 9 0.001 0.001 NUM dti-1406 157 10 ] ] PUNCT dti-1406 157 11 in in ADP dti-1406 157 12 the the DET dti-1406 157 13 ram ram NOUN dti-1406 157 14 test test NOUN dti-1406 157 15 ( ( PUNCT dti-1406 157 16 fig fig NOUN dti-1406 157 17 . . PUNCT dti-1406 157 18 3a 3a NUM dti-1406 157 19 ) ) PUNCT dti-1406 157 20 . . PUNCT dti-1406 158 1 when when SCONJ dti-1406 158 2 the the DET dti-1406 158 3 effects effect NOUN dti-1406 158 4 of of ADP dti-1406 158 5 7 7 NUM dti-1406 158 6 - - PUNCT dti-1406 158 7 ni ni NOUN dti-1406 158 8 ( ( PUNCT dti-1406 158 9 15 15 NUM dti-1406 158 10     SPACE dti-1406 158 11 mg mg PROPN dti-1406 158 12 / / SYM dti-1406 158 13 kg kg PROPN dti-1406 158 14 ) ) PUNCT dti-1406 158 15 and and CCONJ dti-1406 158 16 odq odq NOUN dti-1406 158 17 ( ( PUNCT dti-1406 158 18 3 3 NUM dti-1406 158 19 and and CCONJ dti-1406 158 20 10 10 NUM dti-1406 158 21     SPACE dti-1406 158 22 mg mg PROPN dti-1406 158 23 / / SYM dti-1406 158 24 kg kg PROPN dti-1406 158 25 ) ) PUNCT dti-1406 158 26 on on ADP dti-1406 158 27 the the DET dti-1406 158 28 latency latency NOUN dti-1406 158 29 ( ( PUNCT dti-1406 158 30 time time NOUN dti-1406 158 31 taken take VERB dti-1406 158 32 to to PART dti-1406 158 33 complete complete VERB dti-1406 158 34 the the DET dti-1406 158 35 task task NOUN dti-1406 158 36 ) ) PUNCT dti-1406 158 37 of of ADP dti-1406 158 38 the the DET dti-1406 158 39 animals animal NOUN dti-1406 158 40 in in ADP dti-1406 158 41 the the DET dti-1406 158 42 ram ram NOUN dti-1406 158 43 test test NOUN dti-1406 158 44 were be AUX dti-1406 158 45 evaluated evaluate VERB dti-1406 158 46 , , PUNCT dti-1406 158 47 there there PRON dti-1406 158 48 was be VERB dti-1406 158 49 a a DET dti-1406 158 50 significant significant ADJ dti-1406 158 51 difference difference NOUN dti-1406 158 52 between between ADP dti-1406 158 53 the the DET dti-1406 158 54 groups group NOUN dti-1406 158 55 [ [ X dti-1406 158 56 f(3,29 f(3,29 NOUN dti-1406 158 57 ) ) PUNCT dti-1406 158 58     SPACE dti-1406 159 1 = = NOUN dti-1406 159 2     SPACE dti-1406 159 3 15.11 15.11 NUM dti-1406 159 4 ; ; PUNCT dti-1406 159 5 p p X dti-1406 159 6     SPACE dti-1406 159 7 , , PUNCT dti-1406 159 8     SPACE dti-1406 159 9 0.001 0.001 NUM dti-1406 159 10 ] ] PUNCT dti-1406 159 11 . . PUNCT dti-1406 160 1 7 7 NUM dti-1406 160 2 - - SYM dti-1406 160 3 ni ni PROPN dti-1406 160 4 ( ( PUNCT dti-1406 160 5 15 15 NUM dti-1406 160 6     SPACE dti-1406 160 7 mg mg PROPN dti-1406 160 8 / / SYM dti-1406 160 9 kg kg NOUN dti-1406 160 10 ) ) PUNCT dti-1406 160 11 significantly significantly ADV dti-1406 160 12 enhanced enhance VERB dti-1406 160 13 the the DET dti-1406 160 14 latency latency NOUN dti-1406 160 15 of of ADP dti-1406 160 16 the the DET dti-1406 160 17 animals animal NOUN dti-1406 160 18 ( ( PUNCT dti-1406 160 19 p p X dti-1406 160 20     SPACE dti-1406 160 21 , , PUNCT dti-1406 160 22     SPACE dti-1406 160 23 0.001 0.001 NUM dti-1406 160 24 ) ) PUNCT dti-1406 160 25 , , PUNCT dti-1406 160 26 whereas whereas SCONJ dti-1406 160 27 odq odq PROPN dti-1406 160 28 ( ( PUNCT dti-1406 160 29 3 3 NUM dti-1406 160 30 and and CCONJ dti-1406 160 31 10 10 NUM dti-1406 160 32     SPACE dti-1406 160 33 mg mg PROPN dti-1406 160 34 / / SYM dti-1406 160 35 kg kg PROPN dti-1406 160 36 ) ) PUNCT dti-1406 160 37 had have VERB dti-1406 160 38 no no DET dti-1406 160 39 significant significant ADJ dti-1406 160 40 effect effect NOUN dti-1406 160 41 ( ( PUNCT dti-1406 160 42 p p X dti-1406 160 43     SPACE dti-1406 160 44 . . PUNCT dti-1406 160 45     SPACE dti-1406 160 46 0.05 0.05 NUM dti-1406 160 47 ) ) PUNCT dti-1406 160 48 . . PUNCT dti-1406 161 1 l l NOUN dti-1406 161 2 - - NOUN dti-1406 161 3 arg arg NOUN dti-1406 161 4 ( ( PUNCT dti-1406 161 5 100 100 NUM dti-1406 161 6     SPACE dti-1406 161 7 mg mg PROPN dti-1406 161 8 / / SYM dti-1406 161 9 kg kg PROPN dti-1406 161 10 ) ) PUNCT dti-1406 161 11 combined combine VERB dti-1406 161 12 with with ADP dti-1406 161 13 7 7 NUM dti-1406 161 14 - - PUNCT dti-1406 161 15 ni ni NOUN dti-1406 161 16 ( ( PUNCT dti-1406 161 17 15 15 NUM dti-1406 161 18     SPACE dti-1406 161 19 mg mg PROPN dti-1406 161 20 / / SYM dti-1406 161 21 kg kg NOUN dti-1406 161 22 ) ) PUNCT dti-1406 161 23 significantly significantly ADV dti-1406 161 24 decreased decrease VERB dti-1406 161 25 the the DET dti-1406 161 26 latency latency NOUN dti-1406 161 27 figure figure NOUN dti-1406 161 28 3 3 NUM dti-1406 161 29 . . PUNCT dti-1406 162 1 ( ( PUNCT dti-1406 162 2 a a X dti-1406 162 3 ) ) PUNCT dti-1406 162 4 drug drug NOUN dti-1406 162 5 effects effect NOUN dti-1406 162 6 on on ADP dti-1406 162 7 working work VERB dti-1406 162 8 memory memory NOUN dti-1406 162 9 errors error NOUN dti-1406 162 10 in in ADP dti-1406 162 11 the the DET dti-1406 162 12 ram ram NOUN dti-1406 162 13 test test NOUN dti-1406 162 14 . . PUNCT dti-1406 163 1 ( ( PUNCT dti-1406 163 2 b b X dti-1406 163 3 ) ) PUNCT dti-1406 163 4 drug drug NOUN dti-1406 163 5 effects effect NOUN dti-1406 163 6 on on ADP dti-1406 163 7 the the DET dti-1406 163 8 latency latency NOUN dti-1406 163 9 in in ADP dti-1406 163 10 the the DET dti-1406 163 11 ram ram NOUN dti-1406 163 12 test test NOUN dti-1406 163 13 . . PUNCT dti-1406 164 1 odq odq NOUN dti-1406 164 2 ( ( PUNCT dti-1406 164 3 3 3 NUM dti-1406 164 4 and and CCONJ dti-1406 164 5 10 10 NUM dti-1406 164 6 mg mg NUM dti-1406 164 7 / / SYM dti-1406 164 8 kg kg PROPN dti-1406 164 9 ) ) PUNCT dti-1406 164 10 , , PUNCT dti-1406 164 11 7 7 PROPN dti-1406 164 12 - - SYM dti-1406 164 13 ni ni NOUN dti-1406 164 14 ( ( PUNCT dti-1406 164 15 15 15 NUM dti-1406 164 16 mg mg PROPN dti-1406 164 17 / / SYM dti-1406 164 18 kg kg PROPN dti-1406 164 19 ) ) PUNCT dti-1406 164 20 , , PUNCT dti-1406 164 21 or or CCONJ dti-1406 164 22 l l NOUN dti-1406 164 23 - - NOUN dti-1406 164 24 arginine arginine NOUN dti-1406 164 25 ( ( PUNCT dti-1406 164 26 100 100 NUM dti-1406 164 27 mg mg NUM dti-1406 164 28 / / SYM dti-1406 164 29 kg kg PROPN dti-1406 164 30 ) ) PUNCT dti-1406 164 31 was be AUX dti-1406 164 32 administered administer VERB dti-1406 164 33 30 30 NUM dti-1406 164 34 , , PUNCT dti-1406 164 35 30 30 NUM dti-1406 164 36 , , PUNCT dti-1406 164 37 and and CCONJ dti-1406 164 38 60 60 NUM dti-1406 164 39 minutes minute NOUN dti-1406 164 40 , , PUNCT dti-1406 164 41 respectively respectively ADV dti-1406 164 42 , , PUNCT dti-1406 164 43 prior prior ADV dti-1406 164 44 to to ADP dti-1406 164 45 the the DET dti-1406 164 46 retention retention NOUN dti-1406 164 47 trial trial NOUN dti-1406 164 48 of of ADP dti-1406 164 49 the the DET dti-1406 164 50 ram ram NOUN dti-1406 164 51 test test NOUN dti-1406 164 52 . . PUNCT dti-1406 165 1 results result NOUN dti-1406 165 2 are be AUX dti-1406 165 3 expressed express VERB dti-1406 165 4 as as ADP dti-1406 165 5 the the DET dti-1406 165 6 mean mean PROPN dti-1406 165 7 ± ± NUM dti-1406 165 8 sem sem NOUN dti-1406 165 9 . . PUNCT dti-1406 166 1 n n NOUN dti-1406 167 1 = = NUM dti-1406 167 2 6 6 NUM dti-1406 167 3 per per ADP dti-1406 167 4 group group NOUN dti-1406 167 5 . . PUNCT dti-1406 168 1 * * PUNCT dti-1406 168 2 p p X dti-1406 168 3 , , PUNCT dti-1406 168 4 0.001 0.001 NUM dti-1406 168 5 compared compare VERB dti-1406 168 6 with with ADP dti-1406 168 7 the the DET dti-1406 168 8 control control NOUN dti-1406 168 9 group group NOUN dti-1406 168 10 ; ; PUNCT dti-1406 168 11 # # SYM dti-1406 168 12 p p NOUN dti-1406 168 13 , , PUNCT dti-1406 168 14 0.001 0.001 NUM dti-1406 168 15 compared compare VERB dti-1406 168 16 with with ADP dti-1406 168 17 the the DET dti-1406 168 18 7 7 NUM dti-1406 168 19 - - PUNCT dti-1406 168 20 ni ni NOUN dti-1406 168 21 group group NOUN dti-1406 168 22 . . PUNCT dti-1406 169 1 http://www.la-press.com http://www.la-press.com X dti-1406 169 2 http://www.la-press.com/drug-target-insights-journal-j23 http://www.la-press.com/drug-target-insights-journal-j23 AUX dti-1406 169 3 mutlu mutlu PROPN dti-1406 169 4 et et PROPN dti-1406 169 5 al al PROPN dti-1406 169 6 6 6 NUM dti-1406 169 7 drug drug NOUN dti-1406 169 8 target target NOUN dti-1406 169 9 insights insight NOUN dti-1406 169 10 2015:9 2015:9 NUM dti-1406 169 11 of of ADP dti-1406 169 12 the the DET dti-1406 169 13 ram ram NOUN dti-1406 169 14 test test NOUN dti-1406 169 15 compared compare VERB dti-1406 169 16 with with ADP dti-1406 169 17 7 7 NUM dti-1406 169 18 - - PUNCT dti-1406 169 19 ni ni NOUN dti-1406 169 20 alone alone ADV dti-1406 169 21 [ [ X dti-1406 169 22 f(1,29 f(1,29 X dti-1406 169 23 ) ) PUNCT dti-1406 169 24     SPACE dti-1406 170 1 = = NOUN dti-1406 170 2     SPACE dti-1406 170 3 19,01 19,01 ADJ dti-1406 170 4 ; ; PUNCT dti-1406 170 5 p p X dti-1406 170 6     SPACE dti-1406 170 7 , , PUNCT dti-1406 170 8     SPACE dti-1406 170 9 0.001 0.001 NUM dti-1406 170 10 ; ; PUNCT dti-1406 170 11 fig fig NOUN dti-1406 170 12 . . PUNCT dti-1406 171 1 3b 3b NUM dti-1406 171 2 ] ] PUNCT dti-1406 171 3 . . PUNCT dti-1406 172 1 discussion discussion NOUN dti-1406 172 2 in in ADP dti-1406 172 3 our our PRON dti-1406 172 4 study study NOUN dti-1406 172 5 , , PUNCT dti-1406 172 6 both both CCONJ dti-1406 172 7 the the DET dti-1406 172 8 gc gc PROPN dti-1406 172 9 inhibitor inhibitor NOUN dti-1406 172 10 odq odq NOUN dti-1406 172 11 ( ( PUNCT dti-1406 172 12 3 3 NUM dti-1406 172 13     SPACE dti-1406 172 14 mg mg PROPN dti-1406 172 15 / / SYM dti-1406 172 16 kg kg PROPN dti-1406 172 17 ) ) PUNCT dti-1406 172 18 and and CCONJ dti-1406 172 19 the the DET dti-1406 172 20 nos nos PROPN dti-1406 172 21 inhibitor inhibitor NOUN dti-1406 172 22 7 7 PROPN dti-1406 172 23 - - PUNCT dti-1406 172 24 ni ni PROPN dti-1406 172 25 ( ( PUNCT dti-1406 172 26 15 15 NUM dti-1406 172 27     SPACE dti-1406 172 28 mg mg PROPN dti-1406 172 29 / / SYM dti-1406 172 30 kg kg PROPN dti-1406 172 31 ) ) PUNCT dti-1406 172 32 increased increase VERB dti-1406 172 33 the the DET dti-1406 172 34 retention retention NOUN dti-1406 172 35 latency latency NOUN dti-1406 172 36 in in ADP dti-1406 172 37 the the DET dti-1406 172 38 mepm mepm NOUN dti-1406 172 39 test test NOUN dti-1406 172 40 . . PUNCT dti-1406 173 1 7 7 NUM dti-1406 173 2 - - SYM dti-1406 173 3 ni ni PROPN dti-1406 173 4 ( ( PUNCT dti-1406 173 5 15 15 NUM dti-1406 173 6     SPACE dti-1406 173 7 mg mg PROPN dti-1406 173 8 / / SYM dti-1406 173 9 kg kg PROPN dti-1406 173 10 ) ) PUNCT dti-1406 173 11 and and CCONJ dti-1406 173 12 odq odq NOUN dti-1406 173 13 ( ( PUNCT dti-1406 173 14 10 10 NUM dti-1406 173 15     SPACE dti-1406 173 16 mg mg PROPN dti-1406 173 17 / / SYM dti-1406 173 18 kg kg NOUN dti-1406 173 19 ) ) PUNCT dti-1406 173 20 significantly significantly ADV dti-1406 173 21 increased increase VERB dti-1406 173 22 the the DET dti-1406 173 23 escape escape NOUN dti-1406 173 24 latency latency NOUN dti-1406 173 25 in in ADP dti-1406 173 26 the the DET dti-1406 173 27 second second ADJ dti-1406 173 28 , , PUNCT dti-1406 173 29 third third ADJ dti-1406 173 30 , , PUNCT dti-1406 173 31 and and CCONJ dti-1406 173 32 fourth fourth ADJ dti-1406 173 33 sessions session NOUN dti-1406 173 34 , , PUNCT dti-1406 173 35 diminished diminish VERB dti-1406 173 36 the the DET dti-1406 173 37 time time NOUN dti-1406 173 38 spent spend VERB dti-1406 173 39 in in ADP dti-1406 173 40 the the DET dti-1406 173 41 escape escape NOUN dti-1406 173 42 platform platform NOUN dti-1406 173 43 ’s ’s PART dti-1406 173 44 quadrant quadrant NOUN dti-1406 173 45 , , PUNCT dti-1406 173 46 and and CCONJ dti-1406 173 47 enhanced enhance VERB dti-1406 173 48 the the DET dti-1406 173 49 mean mean ADJ dti-1406 173 50 distance distance NOUN dti-1406 173 51 to to ADP dti-1406 173 52 the the DET dti-1406 173 53 platform platform NOUN dti-1406 173 54 in in ADP dti-1406 173 55 the the DET dti-1406 173 56 probe probe NOUN dti-1406 173 57 trial trial NOUN dti-1406 173 58 of of ADP dti-1406 173 59 the the DET dti-1406 173 60 mwm mwm NOUN dti-1406 173 61 test test NOUN dti-1406 173 62 . . PUNCT dti-1406 174 1 odq odq NOUN dti-1406 174 2 ( ( PUNCT dti-1406 174 3 3 3 NUM dti-1406 174 4 , , PUNCT dti-1406 174 5 10 10 NUM dti-1406 174 6     SPACE dti-1406 174 7 mg mg PROPN dti-1406 174 8 / / SYM dti-1406 174 9 kg kg PROPN dti-1406 174 10 ) ) PUNCT dti-1406 174 11 and and CCONJ dti-1406 174 12 7 7 NUM dti-1406 174 13 - - PUNCT dti-1406 174 14 ni ni PROPN dti-1406 174 15 ( ( PUNCT dti-1406 174 16 15 15 NUM dti-1406 174 17     SPACE dti-1406 174 18 mg mg PROPN dti-1406 174 19 / / SYM dti-1406 174 20 kg kg NOUN dti-1406 174 21 ) ) PUNCT dti-1406 174 22 significantly significantly ADV dti-1406 174 23 increased increase VERB dti-1406 174 24 the the DET dti-1406 174 25 number number NOUN dti-1406 174 26 of of ADP dti-1406 174 27 errors error NOUN dti-1406 174 28 , , PUNCT dti-1406 174 29 whereas whereas SCONJ dti-1406 174 30 only only ADV dti-1406 174 31 7 7 NUM dti-1406 174 32 - - SYM dti-1406 174 33 ni ni PROPN dti-1406 174 34 increased increase VERB dti-1406 174 35 the the DET dti-1406 174 36 latency latency NOUN dti-1406 174 37 in in ADP dti-1406 174 38 the the DET dti-1406 174 39 ram ram NOUN dti-1406 174 40 test test NOUN dti-1406 174 41 . . PUNCT dti-1406 175 1 the the DET dti-1406 175 2 7 7 NUM dti-1406 175 3 - - PUNCT dti-1406 175 4 ni ni NOUN dti-1406 175 5 ( ( PUNCT dti-1406 175 6 15 15 NUM dti-1406 175 7     SPACE dti-1406 175 8 mg mg PROPN dti-1406 175 9 / / SYM dti-1406 175 10 kg)-induced kg)-induce VERB dti-1406 175 11 effects effect NOUN dti-1406 175 12 in in ADP dti-1406 175 13 the the DET dti-1406 175 14 mepm mepm NOUN dti-1406 175 15 , , PUNCT dti-1406 175 16 mwm mwm NOUN dti-1406 175 17 , , PUNCT dti-1406 175 18 and and CCONJ dti-1406 175 19 ram ram NOUN dti-1406 175 20 tests test NOUN dti-1406 175 21 were be AUX dti-1406 175 22 reversed reverse VERB dti-1406 175 23 by by ADP dti-1406 175 24 the the DET dti-1406 175 25 no no DET dti-1406 175 26 precursor precursor NOUN dti-1406 175 27 , , PUNCT dti-1406 175 28 l l NOUN dti-1406 175 29 - - NOUN dti-1406 175 30 arginine arginine NOUN dti-1406 175 31 ( ( PUNCT dti-1406 175 32 100 100 NUM dti-1406 175 33     SPACE dti-1406 175 34 mg mg PROPN dti-1406 175 35 / / SYM dti-1406 175 36 kg kg PROPN dti-1406 175 37 ) ) PUNCT dti-1406 175 38 . . PUNCT dti-1406 176 1 mwm mwm NOUN dti-1406 176 2 is be AUX dti-1406 176 3 a a DET dti-1406 176 4 spatial spatial ADJ dti-1406 176 5 , , PUNCT dti-1406 176 6 long long ADJ dti-1406 176 7 - - PUNCT dti-1406 176 8 term term NOUN dti-1406 176 9 memory memory NOUN dti-1406 176 10 evaluation evaluation NOUN dti-1406 176 11 test.38 test.38 NOUN dti-1406 176 12 the the DET dti-1406 176 13 daily daily ADJ dti-1406 176 14 decrease decrease NOUN dti-1406 176 15 in in ADP dti-1406 176 16 escape escape NOUN dti-1406 176 17 latencies latency NOUN dti-1406 176 18 reflects reflect VERB dti-1406 176 19 learning learn VERB dti-1406 176 20 , , PUNCT dti-1406 176 21 and and CCONJ dti-1406 176 22 it it PRON dti-1406 176 23 is be AUX dti-1406 176 24 related relate VERB dti-1406 176 25 to to ADP dti-1406 176 26 long long ADJ dti-1406 176 27 - - PUNCT dti-1406 176 28 term term NOUN dti-1406 176 29 reference reference NOUN dti-1406 176 30 memory memory NOUN dti-1406 176 31 . . PUNCT dti-1406 177 1 this this DET dti-1406 177 2 study study NOUN dti-1406 177 3 revealed reveal VERB dti-1406 177 4 that that SCONJ dti-1406 177 5 odq odq NOUN dti-1406 177 6 ( ( PUNCT dti-1406 177 7 10 10 NUM dti-1406 177 8     SPACE dti-1406 177 9 mg mg PROPN dti-1406 177 10 / / SYM dti-1406 177 11 kg kg PROPN dti-1406 177 12 ) ) PUNCT dti-1406 177 13 and and CCONJ dti-1406 177 14 7 7 NUM dti-1406 177 15 - - PUNCT dti-1406 177 16 ni ni PROPN dti-1406 177 17 ( ( PUNCT dti-1406 177 18 15 15 NUM dti-1406 177 19     SPACE dti-1406 177 20 mg mg PROPN dti-1406 177 21 / / SYM dti-1406 177 22 kg kg PROPN dti-1406 177 23 ) ) PUNCT dti-1406 177 24 increased increase VERB dti-1406 177 25 the the DET dti-1406 177 26 escape escape NOUN dti-1406 177 27 latency latency NOUN dti-1406 177 28 during during ADP dti-1406 177 29 the the DET dti-1406 177 30 acquisition acquisition NOUN dti-1406 177 31 sessions session NOUN dti-1406 177 32 , , PUNCT dti-1406 177 33 diminished diminish VERB dti-1406 177 34 the the DET dti-1406 177 35 time time NOUN dti-1406 177 36 spent spend VERB dti-1406 177 37 in in ADP dti-1406 177 38 the the DET dti-1406 177 39 escape escape NOUN dti-1406 177 40 platform platform NOUN dti-1406 177 41 quadrant quadrant NOUN dti-1406 177 42 , , PUNCT dti-1406 177 43 and and CCONJ dti-1406 177 44 enhanced enhance VERB dti-1406 177 45 the the DET dti-1406 177 46 mean mean ADJ dti-1406 177 47 distance distance NOUN dti-1406 177 48 traveled travel VERB dti-1406 177 49 to to ADP dti-1406 177 50 the the DET dti-1406 177 51 platform platform NOUN dti-1406 177 52 during during ADP dti-1406 177 53 the the DET dti-1406 177 54 probe probe NOUN dti-1406 177 55 test test NOUN dti-1406 177 56 . . PUNCT dti-1406 178 1 therefore therefore ADV dti-1406 178 2 , , PUNCT dti-1406 178 3 both both DET dti-1406 178 4 odq odq NOUN dti-1406 178 5 and and CCONJ dti-1406 178 6 7 7 PROPN dti-1406 178 7 - - PUNCT dti-1406 178 8 ni ni PROPN dti-1406 178 9 disturbed disturb VERB dti-1406 178 10 the the DET dti-1406 178 11 spatial spatial ADJ dti-1406 178 12 memory memory NOUN dti-1406 178 13 . . PUNCT dti-1406 179 1 the the DET dti-1406 179 2 drug drug NOUN dti-1406 179 3 treatment treatment NOUN dti-1406 179 4 did do AUX dti-1406 179 5 not not PART dti-1406 179 6 alter alter VERB dti-1406 179 7 the the DET dti-1406 179 8 swimming swimming NOUN dti-1406 179 9 speed speed NOUN dti-1406 179 10 of of ADP dti-1406 179 11 the the DET dti-1406 179 12 mice mouse NOUN dti-1406 179 13 , , PUNCT dti-1406 179 14 which which PRON dti-1406 179 15 suggests suggest VERB dti-1406 179 16 odq odq NOUN dti-1406 179 17 and and CCONJ dti-1406 179 18 7 7 PROPN dti-1406 179 19 - - PUNCT dti-1406 179 20 ni ni PROPN dti-1406 179 21 did do AUX dti-1406 179 22 not not PART dti-1406 179 23 alter alter VERB dti-1406 179 24 their their PRON dti-1406 179 25 motor motor NOUN dti-1406 179 26 activity activity NOUN dti-1406 179 27 . . PUNCT dti-1406 180 1 because because SCONJ dti-1406 180 2 the the DET dti-1406 180 3 position position NOUN dti-1406 180 4 of of ADP dti-1406 180 5 the the DET dti-1406 180 6 platform platform NOUN dti-1406 180 7 did do AUX dti-1406 180 8 not not PART dti-1406 180 9 change change VERB dti-1406 180 10 throughout throughout ADP dti-1406 180 11 the the DET dti-1406 180 12 experiment experiment NOUN dti-1406 180 13 , , PUNCT dti-1406 180 14 these these DET dti-1406 180 15 results result NOUN dti-1406 180 16 indicate indicate VERB dti-1406 180 17 that that SCONJ dti-1406 180 18 odq odq NOUN dti-1406 180 19 and and CCONJ dti-1406 180 20 7 7 PROPN dti-1406 180 21 - - PUNCT dti-1406 180 22 ni ni PROPN dti-1406 180 23 disturbed disturb VERB dti-1406 180 24 the the DET dti-1406 180 25 reference reference NOUN dti-1406 180 26 spatial spatial ADJ dti-1406 180 27 memory memory NOUN dti-1406 180 28 . . PUNCT dti-1406 181 1 it it PRON dti-1406 181 2 has have AUX dti-1406 181 3 been be AUX dti-1406 181 4 shown show VERB dti-1406 181 5 that that SCONJ dti-1406 181 6 the the DET dti-1406 181 7 ability ability NOUN dti-1406 181 8 to to PART dti-1406 181 9 make make VERB dti-1406 181 10 a a DET dti-1406 181 11 series series NOUN dti-1406 181 12 of of ADP dti-1406 181 13 correct correct ADJ dti-1406 181 14 choices choice NOUN dti-1406 181 15 in in ADP dti-1406 181 16 the the DET dti-1406 181 17 ram ram NOUN dti-1406 181 18 test test NOUN dti-1406 181 19 depends depend VERB dti-1406 181 20 on on ADP dti-1406 181 21 the the DET dti-1406 181 22 spatial spatial ADJ dti-1406 181 23 information information NOUN dti-1406 181 24 from from ADP dti-1406 181 25 extramaze extramaze ADJ dti-1406 181 26 cues.39 cues.39 NOUN dti-1406 181 27 in in ADP dti-1406 181 28 our our PRON dti-1406 181 29 protocol protocol NOUN dti-1406 181 30 , , PUNCT dti-1406 181 31 the the DET dti-1406 181 32 effects effect NOUN dti-1406 181 33 of of ADP dti-1406 181 34 the the DET dti-1406 181 35 drugs drug NOUN dti-1406 181 36 on on ADP dti-1406 181 37 spatial spatial ADJ dti-1406 181 38 memory memory NOUN dti-1406 181 39 were be AUX dti-1406 181 40 evaluated evaluate VERB dti-1406 181 41 because because SCONJ dti-1406 181 42 performance performance NOUN dti-1406 181 43 in in ADP dti-1406 181 44 the the DET dti-1406 181 45 maze maze NOUN dti-1406 181 46 requires require VERB dti-1406 181 47 sufficient sufficient ADJ dti-1406 181 48 memory memory NOUN dti-1406 181 49 of of ADP dti-1406 181 50 the the DET dti-1406 181 51 spatial spatial ADJ dti-1406 181 52 environment environment NOUN dti-1406 181 53 . . PUNCT dti-1406 182 1 each each DET dti-1406 182 2 arm arm NOUN dti-1406 182 3 was be AUX dti-1406 182 4 baited bait VERB dti-1406 182 5 with with ADP dti-1406 182 6 food food NOUN dti-1406 182 7 , , PUNCT dti-1406 182 8 and and CCONJ dti-1406 182 9 reentry reentry NOUN dti-1406 182 10 to to ADP dti-1406 182 11 a a DET dti-1406 182 12 previously previously ADV dti-1406 182 13 visited visit VERB dti-1406 182 14 arm arm NOUN dti-1406 182 15 was be AUX dti-1406 182 16 categorized categorize VERB dti-1406 182 17 as as ADP dti-1406 182 18 an an DET dti-1406 182 19 error error NOUN dti-1406 182 20 ; ; PUNCT dti-1406 182 21 thus thus ADV dti-1406 182 22 , , PUNCT dti-1406 182 23 spatial spatial ADJ dti-1406 182 24 working working NOUN dti-1406 182 25 memory memory NOUN dti-1406 182 26 was be AUX dti-1406 182 27 thought think VERB dti-1406 182 28 to to PART dti-1406 182 29 be be AUX dti-1406 182 30 examined.39 examined.39 VERB dti-1406 182 31 both both DET dti-1406 182 32 odq odq NOUN dti-1406 182 33 ( ( PUNCT dti-1406 182 34 3 3 NUM dti-1406 182 35 and and CCONJ dti-1406 182 36 10 10 NUM dti-1406 182 37     SPACE dti-1406 182 38 mg mg PROPN dti-1406 182 39 / / SYM dti-1406 182 40 kg kg PROPN dti-1406 182 41 ) ) PUNCT dti-1406 182 42 and and CCONJ dti-1406 182 43 7 7 NUM dti-1406 182 44 - - PUNCT dti-1406 182 45 ni ni PROPN dti-1406 182 46 ( ( PUNCT dti-1406 182 47 15 15 NUM dti-1406 182 48     SPACE dti-1406 182 49 mg mg PROPN dti-1406 182 50 / / SYM dti-1406 182 51 kg kg NOUN dti-1406 182 52 ) ) PUNCT dti-1406 182 53 disturbed disturb VERB dti-1406 182 54 the the DET dti-1406 182 55 spatial spatial ADJ dti-1406 182 56 working working NOUN dti-1406 182 57 memory memory NOUN dti-1406 182 58 in in ADP dti-1406 182 59 the the DET dti-1406 182 60 ram ram NOUN dti-1406 182 61 test test NOUN dti-1406 182 62 in in ADP dti-1406 182 63 our our PRON dti-1406 182 64 study study NOUN dti-1406 182 65 . . PUNCT dti-1406 183 1 the the DET dti-1406 183 2 mepm mepm PROPN dti-1406 183 3 test test NOUN dti-1406 183 4 is be AUX dti-1406 183 5 a a DET dti-1406 183 6 simple simple ADJ dti-1406 183 7 method method NOUN dti-1406 183 8 that that PRON dti-1406 183 9 evaluates evaluate VERB dti-1406 183 10 spatial spatial ADJ dti-1406 183 11 memory memory NOUN dti-1406 183 12 . . PUNCT dti-1406 184 1 a a DET dti-1406 184 2 shortened shorten VERB dti-1406 184 3 transfer transfer NOUN dti-1406 184 4 latency latency NOUN dti-1406 184 5 in in ADP dti-1406 184 6 the the DET dti-1406 184 7 second second ADJ dti-1406 184 8 trial trial NOUN dti-1406 184 9 is be AUX dti-1406 184 10 used use VERB dti-1406 184 11 as as ADP dti-1406 184 12 a a DET dti-1406 184 13 parameter parameter NOUN dti-1406 184 14 to to PART dti-1406 184 15 measure measure VERB dti-1406 184 16 the the DET dti-1406 184 17 retention retention NOUN dti-1406 184 18 or or CCONJ dti-1406 184 19 consolidation consolidation NOUN dti-1406 184 20 of of ADP dti-1406 184 21 memory memory NOUN dti-1406 184 22 , , PUNCT dti-1406 184 23 and and CCONJ dti-1406 184 24 drug drug NOUN dti-1406 184 25 treatment treatment NOUN dti-1406 184 26 prior prior ADV dti-1406 184 27 to to ADP dti-1406 184 28 the the DET dti-1406 184 29 first first ADJ dti-1406 184 30 day day NOUN dti-1406 184 31 may may AUX dti-1406 184 32 be be AUX dti-1406 184 33 utilized utilize VERB dti-1406 184 34 to to PART dti-1406 184 35 determine determine VERB dti-1406 184 36 the the DET dti-1406 184 37 effects effect NOUN dti-1406 184 38 on on ADP dti-1406 184 39 memory memory NOUN dti-1406 184 40 acquisition.40 acquisition.40 NOUN dti-1406 184 41 the the DET dti-1406 184 42 evaluation evaluation NOUN dti-1406 184 43 of of ADP dti-1406 184 44 drug drug NOUN dti-1406 184 45 effects effect NOUN dti-1406 184 46 in in ADP dti-1406 184 47 the the DET dti-1406 184 48 first first ADJ dti-1406 184 49 trial trial NOUN dti-1406 184 50 may may AUX dti-1406 184 51 be be AUX dti-1406 184 52 confounded confound VERB dti-1406 184 53 by by ADP dti-1406 184 54 nonspecific nonspecific ADJ dti-1406 184 55 effects effect NOUN dti-1406 184 56 , , PUNCT dti-1406 184 57 such such ADJ dti-1406 184 58 as as ADP dti-1406 184 59 effects effect NOUN dti-1406 184 60 on on ADP dti-1406 184 61 anxiety anxiety NOUN dti-1406 184 62 , , PUNCT dti-1406 184 63 locomotion locomotion NOUN dti-1406 184 64 , , PUNCT dti-1406 184 65 and and CCONJ dti-1406 184 66 motility.41 motility.41 NOUN dti-1406 184 67 since since SCONJ dti-1406 184 68 there there PRON dti-1406 184 69 was be VERB dti-1406 184 70 no no DET dti-1406 184 71 significant significant ADJ dti-1406 184 72 difference difference NOUN dti-1406 184 73 between between ADP dti-1406 184 74 groups group NOUN dti-1406 184 75 for for ADP dti-1406 184 76 the the DET dti-1406 184 77 first first ADJ dti-1406 184 78 - - PUNCT dti-1406 184 79 day day NOUN dti-1406 184 80 latency latency NOUN dti-1406 184 81 in in ADP dti-1406 184 82 the the DET dti-1406 184 83 mepm mepm NOUN dti-1406 184 84 test test NOUN dti-1406 184 85 , , PUNCT dti-1406 184 86 we we PRON dti-1406 184 87 can can AUX dti-1406 184 88 exclude exclude VERB dti-1406 184 89 these these DET dti-1406 184 90 nonspecific nonspecific ADJ dti-1406 184 91 effects effect NOUN dti-1406 184 92 . . PUNCT dti-1406 185 1 both both DET dti-1406 185 2 odq odq NOUN dti-1406 185 3 ( ( PUNCT dti-1406 185 4 3 3 NUM dti-1406 185 5     SPACE dti-1406 185 6 mg mg PROPN dti-1406 185 7 / / SYM dti-1406 185 8 kg kg PROPN dti-1406 185 9 ) ) PUNCT dti-1406 185 10 and and CCONJ dti-1406 185 11 7 7 NUM dti-1406 185 12 - - PUNCT dti-1406 185 13 ni ni PROPN dti-1406 185 14 ( ( PUNCT dti-1406 185 15 15 15 NUM dti-1406 185 16     SPACE dti-1406 185 17 mg mg PROPN dti-1406 185 18 / / SYM dti-1406 185 19 kg kg NOUN dti-1406 185 20 ) ) PUNCT dti-1406 185 21 treatment treatment NOUN dti-1406 185 22 led lead VERB dti-1406 185 23 to to ADP dti-1406 185 24 memory memory NOUN dti-1406 185 25 deterioration deterioration NOUN dti-1406 185 26 in in ADP dti-1406 185 27 the the DET dti-1406 185 28 epm epm NOUN dti-1406 185 29 test test NOUN dti-1406 185 30 in in ADP dti-1406 185 31 our our PRON dti-1406 185 32 study study NOUN dti-1406 185 33 , , PUNCT dti-1406 185 34 which which PRON dti-1406 185 35 is be AUX dti-1406 185 36 in in ADP dti-1406 185 37 accordance accordance NOUN dti-1406 185 38 with with ADP dti-1406 185 39 previous previous ADJ dti-1406 185 40 studies.28,37,42 studies.28,37,42 NOUN dti-1406 185 41 the the DET dti-1406 185 42 effects effect NOUN dti-1406 185 43 of of ADP dti-1406 185 44 odq odq NOUN dti-1406 185 45 did do AUX dti-1406 185 46 not not PART dti-1406 185 47 follow follow VERB dti-1406 185 48 a a DET dti-1406 185 49 typical typical ADJ dti-1406 185 50 dose dose NOUN dti-1406 185 51 – – PUNCT dti-1406 185 52 response response NOUN dti-1406 185 53 curve curve NOUN dti-1406 185 54 of of ADP dti-1406 185 55 a a DET dti-1406 185 56 drug drug NOUN dti-1406 185 57 . . PUNCT dti-1406 186 1 the the DET dti-1406 186 2 experimental experimental ADJ dti-1406 186 3 condition condition NOUN dti-1406 186 4 can can AUX dti-1406 186 5 cause cause VERB dti-1406 186 6 some some DET dti-1406 186 7 differences difference NOUN dti-1406 186 8 between between ADP dti-1406 186 9 the the DET dti-1406 186 10 results result NOUN dti-1406 186 11 . . PUNCT dti-1406 187 1 we we PRON dti-1406 187 2 studied study VERB dti-1406 187 3 with with ADP dti-1406 187 4 standard standard ADJ dti-1406 187 5 experimental experimental ADJ dti-1406 187 6 conditions condition NOUN dti-1406 187 7 and and CCONJ dti-1406 187 8 standard standard ADJ dti-1406 187 9 equipment equipment NOUN dti-1406 187 10 and and CCONJ dti-1406 187 11 obtained obtain VERB dti-1406 187 12 these these DET dti-1406 187 13 results result NOUN dti-1406 187 14 . . PUNCT dti-1406 188 1 recent recent ADJ dti-1406 188 2 studies study NOUN dti-1406 188 3 suggest suggest VERB dti-1406 188 4 that that SCONJ dti-1406 188 5 both both CCONJ dti-1406 188 6 neuronal neuronal ADJ dti-1406 188 7 ( ( PUNCT dti-1406 188 8 nnos nnos ADJ dti-1406 188 9 ) ) PUNCT dti-1406 188 10 and and CCONJ dti-1406 188 11 endothelial endothelial NOUN dti-1406 188 12 ( ( PUNCT dti-1406 188 13 enos eno NOUN dti-1406 188 14 ) ) PUNCT dti-1406 188 15 nitric nitric ADJ dti-1406 188 16 oxide oxide NOUN dti-1406 188 17 isoforms isoform NOUN dti-1406 188 18 have have VERB dti-1406 188 19 a a DET dti-1406 188 20 role role NOUN dti-1406 188 21 in in ADP dti-1406 188 22 memory memory NOUN dti-1406 188 23 formation formation NOUN dti-1406 188 24 . . PUNCT dti-1406 189 1 additionally additionally ADV dti-1406 189 2 , , PUNCT dti-1406 189 3 in in ADP dti-1406 189 4 a a DET dti-1406 189 5 passive passive ADJ dti-1406 189 6 avoidance avoidance NOUN dti-1406 189 7 test test NOUN dti-1406 189 8 , , PUNCT dti-1406 189 9 nnos nno NOUN dti-1406 189 10 can can AUX dti-1406 189 11 not not PART dti-1406 189 12 substitute substitute VERB dti-1406 189 13 for for ADP dti-1406 189 14 the the DET dti-1406 189 15 role role NOUN dti-1406 189 16 of of ADP dti-1406 189 17 enos eno NOUN dti-1406 189 18 on on ADP dti-1406 189 19 ltp.43 ltp.43 ADJ dti-1406 189 20 in in ADP dti-1406 189 21 research research NOUN dti-1406 189 22 using use VERB dti-1406 189 23 “ " PUNCT dti-1406 189 24 knock knock VERB dti-1406 189 25 - - PUNCT dti-1406 189 26 out out ADP dti-1406 189 27 ” " PUNCT dti-1406 189 28 mice mouse NOUN dti-1406 189 29 , , PUNCT dti-1406 189 30 it it PRON dti-1406 189 31 has have AUX dti-1406 189 32 been be AUX dti-1406 189 33 demonstrated demonstrate VERB dti-1406 189 34 that that SCONJ dti-1406 189 35 both both CCONJ dti-1406 189 36 neuronal neuronal ADJ dti-1406 189 37 and and CCONJ dti-1406 189 38 endothelial endothelial NOUN dti-1406 189 39 nos no NOUN dti-1406 189 40 isoforms isoform NOUN dti-1406 189 41 were be AUX dti-1406 189 42 expressed express VERB dti-1406 189 43 in in ADP dti-1406 189 44 hippocampal hippocampal ADJ dti-1406 189 45 ca1 ca1 NOUN dti-1406 189 46 pyramidal pyramidal ADJ dti-1406 189 47 cells cell NOUN dti-1406 189 48 , , PUNCT dti-1406 189 49 and and CCONJ dti-1406 189 50 both both CCONJ dti-1406 189 51 endothelial endothelial ADJ dti-1406 189 52 and and CCONJ dti-1406 189 53 neuronal neuronal ADJ dti-1406 189 54 nos nos PROPN dti-1406 189 55 deletion deletion NOUN dti-1406 189 56 resulted result VERB dti-1406 189 57 in in ADP dti-1406 189 58 the the DET dti-1406 189 59 loss loss NOUN dti-1406 189 60 of of ADP dti-1406 189 61 ltp.44 ltp.44 NOUN dti-1406 189 62 in in ADP dti-1406 189 63 contrast contrast NOUN dti-1406 189 64 , , PUNCT dti-1406 189 65 when when SCONJ dti-1406 189 66 only only ADV dti-1406 189 67 one one NUM dti-1406 189 68 isoform isoform NOUN dti-1406 189 69 mutant mutant NOUN dti-1406 189 70 was be AUX dti-1406 189 71 used use VERB dti-1406 189 72 , , PUNCT dti-1406 189 73 the the DET dti-1406 189 74 mice mouse NOUN dti-1406 189 75 had have AUX dti-1406 189 76 preserved preserve VERB dti-1406 189 77 their their PRON dti-1406 189 78 normal normal ADJ dti-1406 189 79 ltp ltp PROPN dti-1406 189 80 capacity.44 capacity.44 NOUN dti-1406 189 81 taken take VERB dti-1406 189 82 together together ADV dti-1406 189 83 , , PUNCT dti-1406 189 84 these these DET dti-1406 189 85 results result NOUN dti-1406 189 86 support support VERB dti-1406 189 87 the the DET dti-1406 189 88 claim claim NOUN dti-1406 189 89 that that SCONJ dti-1406 189 90 both both DET dti-1406 189 91 isoforms isoform NOUN dti-1406 189 92 have have AUX dti-1406 189 93 a a DET dti-1406 189 94 role role NOUN dti-1406 189 95 in in ADP dti-1406 189 96 ltp ltp PROPN dti-1406 189 97 and and CCONJ dti-1406 189 98 can can AUX dti-1406 189 99 substitute substitute VERB dti-1406 189 100 for for ADP dti-1406 189 101 each each DET dti-1406 189 102 other other ADJ dti-1406 189 103 ; ; PUNCT dti-1406 189 104 however however ADV dti-1406 189 105 , , PUNCT dti-1406 189 106 the the DET dti-1406 189 107 mechanisms mechanism NOUN dti-1406 189 108 that that PRON dti-1406 189 109 underlie underlie VERB dti-1406 189 110 their their PRON dti-1406 189 111 actions action NOUN dti-1406 189 112 and and CCONJ dti-1406 189 113 the the DET dti-1406 189 114 degree degree NOUN dti-1406 189 115 to to PART dti-1406 189 116 which which PRON dti-1406 189 117 enos enos NOUN dti-1406 189 118 can can AUX dti-1406 189 119 compensate compensate VERB dti-1406 189 120 nnos nno NOUN dti-1406 189 121 remain remain VERB dti-1406 189 122 unknown unknown ADJ dti-1406 189 123 . . PUNCT dti-1406 190 1 these these DET dti-1406 190 2 findings finding NOUN dti-1406 190 3 can can AUX dti-1406 190 4 explain explain VERB dti-1406 190 5 why why SCONJ dti-1406 190 6 the the DET dti-1406 190 7 nonselective nonselective ADJ dti-1406 190 8 nnos nno NOUN dti-1406 190 9 and and CCONJ dti-1406 190 10 enos eno VERB dti-1406 190 11 inhibitor inhibitor PROPN dti-1406 190 12 7 7 PROPN dti-1406 190 13 - - PUNCT dti-1406 190 14 ni ni ADJ dti-1406 190 15 impaired impaired ADJ dti-1406 190 16 learning learning NOUN dti-1406 190 17 and and CCONJ dti-1406 190 18 memory memory NOUN dti-1406 190 19 in in ADP dti-1406 190 20 our our PRON dti-1406 190 21 study study NOUN dti-1406 190 22 , , PUNCT dti-1406 190 23 as as ADV dti-1406 190 24 well well ADV dti-1406 190 25 as as ADP dti-1406 190 26 the the DET dti-1406 190 27 discrepancies discrepancy NOUN dti-1406 190 28 in in ADP dti-1406 190 29 the the DET dti-1406 190 30 studies study NOUN dti-1406 190 31 with with ADP dti-1406 190 32 nos nos PROPN dti-1406 190 33 inhibitors inhibitor NOUN dti-1406 190 34 on on ADP dti-1406 190 35 memory memory NOUN dti-1406 190 36 . . PUNCT dti-1406 191 1 the the DET dti-1406 191 2 differences difference NOUN dti-1406 191 3 between between ADP dti-1406 191 4 the the DET dti-1406 191 5 animal animal NOUN dti-1406 191 6 strains strain NOUN dti-1406 191 7 , , PUNCT dti-1406 191 8 types type NOUN dti-1406 191 9 , , PUNCT dti-1406 191 10 and and CCONJ dti-1406 191 11 protocols protocol NOUN dti-1406 191 12 of of ADP dti-1406 191 13 the the DET dti-1406 191 14 test test NOUN dti-1406 191 15 , , PUNCT dti-1406 191 16 drug drug NOUN dti-1406 191 17 type type NOUN dti-1406 191 18 , , PUNCT dti-1406 191 19 pharmacokinetics pharmacokinetic NOUN dti-1406 191 20 , , PUNCT dti-1406 191 21 specificity specificity NOUN dti-1406 191 22 , , PUNCT dti-1406 191 23 dose dose NOUN dti-1406 191 24 , , PUNCT dti-1406 191 25 and and CCONJ dti-1406 191 26 administration administration NOUN dti-1406 191 27 route route NOUN dti-1406 191 28 of of ADP dti-1406 191 29 the the DET dti-1406 191 30 drugs drug NOUN dti-1406 191 31 can can AUX dti-1406 191 32 explain explain VERB dti-1406 191 33 , , PUNCT dti-1406 191 34 in in ADP dti-1406 191 35 part part NOUN dti-1406 191 36 , , PUNCT dti-1406 191 37 the the DET dti-1406 191 38 discrepancies discrepancy NOUN dti-1406 191 39 between between ADP dti-1406 191 40 different different ADJ dti-1406 191 41 studies study NOUN dti-1406 191 42 . . PUNCT dti-1406 192 1 no no DET dti-1406 192 2 inhibitors inhibitor NOUN dti-1406 192 3 or or CCONJ dti-1406 192 4 donors donor NOUN dti-1406 192 5 are be AUX dti-1406 192 6 known know VERB dti-1406 192 7 to to PART dti-1406 192 8 exert exert VERB dti-1406 192 9 effects effect NOUN dti-1406 192 10 on on ADP dti-1406 192 11 blood blood NOUN dti-1406 192 12 pressure.45 pressure.45 ADV dti-1406 192 13 no no DET dti-1406 192 14 donors donor NOUN dti-1406 192 15 can can AUX dti-1406 192 16 cause cause VERB dti-1406 192 17 hypotension hypotension NOUN dti-1406 192 18 , , PUNCT dti-1406 192 19 whereas whereas SCONJ dti-1406 192 20 nos no NOUN dti-1406 192 21 inhibitors inhibitor NOUN dti-1406 192 22 can can AUX dti-1406 192 23 lead lead VERB dti-1406 192 24 to to ADP dti-1406 192 25 hypertension hypertension NOUN dti-1406 192 26 . . PUNCT dti-1406 193 1 the the DET dti-1406 193 2 effects effect NOUN dti-1406 193 3 of of ADP dti-1406 193 4 these these DET dti-1406 193 5 drug drug NOUN dti-1406 193 6 groups group NOUN dti-1406 193 7 on on ADP dti-1406 193 8 cognitive cognitive ADJ dti-1406 193 9 functions function NOUN dti-1406 193 10 can can AUX dti-1406 193 11 be be AUX dti-1406 193 12 the the DET dti-1406 193 13 result result NOUN dti-1406 193 14 of of ADP dti-1406 193 15 their their PRON dti-1406 193 16 effects effect NOUN dti-1406 193 17 on on ADP dti-1406 193 18 cardiovascular cardiovascular ADJ dti-1406 193 19 functions function NOUN dti-1406 193 20 . . PUNCT dti-1406 194 1 there there PRON dti-1406 194 2 is be VERB dti-1406 194 3 controversy controversy NOUN dti-1406 194 4 regarding regard VERB dti-1406 194 5 the the DET dti-1406 194 6 effects effect NOUN dti-1406 194 7 of of ADP dti-1406 194 8 7 7 NUM dti-1406 194 9 - - PUNCT dti-1406 194 10 ni ni NOUN dti-1406 194 11 on on ADP dti-1406 194 12 blood blood NOUN dti-1406 194 13 pressure pressure NOUN dti-1406 194 14 , , PUNCT dti-1406 194 15 although although SCONJ dti-1406 194 16 prickaerts prickaert NOUN dti-1406 194 17 et et NOUN dti-1406 194 18 al14 al14 PROPN dti-1406 194 19 reported report VERB dti-1406 194 20 that that SCONJ dti-1406 194 21 the the DET dti-1406 194 22 disruption disruption NOUN dti-1406 194 23 of of ADP dti-1406 194 24 7 7 PROPN dti-1406 194 25 - - PUNCT dti-1406 194 26 ni ni NOUN dti-1406 194 27 effects effect NOUN dti-1406 194 28 was be AUX dti-1406 194 29 not not PART dti-1406 194 30 correlated correlate VERB dti-1406 194 31 with with ADP dti-1406 194 32 its its PRON dti-1406 194 33 effects effect NOUN dti-1406 194 34 on on ADP dti-1406 194 35 blood blood NOUN dti-1406 194 36 pressure pressure NOUN dti-1406 194 37 . . PUNCT dti-1406 195 1 hölscher hölscher NOUN dti-1406 195 2 et et NOUN dti-1406 196 1 al26 al26 PROPN dti-1406 196 2 observed observe VERB dti-1406 196 3 that that SCONJ dti-1406 196 4 30 30 NUM dti-1406 196 5     SPACE dti-1406 196 6 mg mg PROPN dti-1406 196 7 / / SYM dti-1406 196 8 kg kg PROPN dti-1406 196 9 7 7 NUM dti-1406 196 10 - - PUNCT dti-1406 196 11 ni ni ADJ dti-1406 196 12 impaired impair VERB dti-1406 196 13 spatial spatial ADJ dti-1406 196 14 learning learning NOUN dti-1406 196 15 without without ADP dti-1406 196 16 changing change VERB dti-1406 196 17 blood blood NOUN dti-1406 196 18 pressure pressure NOUN dti-1406 196 19 in in ADP dti-1406 196 20 both both CCONJ dti-1406 196 21 the the DET dti-1406 196 22 water water NOUN dti-1406 196 23 maze maze NOUN dti-1406 196 24 and and CCONJ dti-1406 196 25 eight eight NUM dti-1406 196 26 - - PUNCT dti-1406 196 27 arm arm NOUN dti-1406 196 28 radial radial ADJ dti-1406 196 29 maze maze NOUN dti-1406 196 30 tests test NOUN dti-1406 196 31 . . PUNCT dti-1406 197 1 in in ADP dti-1406 197 2 our our PRON dti-1406 197 3 study study NOUN dti-1406 197 4 , , PUNCT dti-1406 197 5 we we PRON dti-1406 197 6 administered administer VERB dti-1406 197 7 the the DET dti-1406 197 8 drugs drug NOUN dti-1406 197 9 systematically systematically ADV dti-1406 197 10 ; ; PUNCT dti-1406 197 11 thus thus ADV dti-1406 197 12 , , PUNCT dti-1406 197 13 we we PRON dti-1406 197 14 could could AUX dti-1406 197 15 not not PART dti-1406 197 16 avoid avoid VERB dti-1406 197 17 nonspecific nonspecific ADJ dti-1406 197 18 effects effect NOUN dti-1406 197 19 , , PUNCT dti-1406 197 20 such such ADJ dti-1406 197 21 as as ADP dti-1406 197 22 hypertension hypertension NOUN dti-1406 197 23 . . PUNCT dti-1406 198 1 however however ADV dti-1406 198 2 , , PUNCT dti-1406 198 3 in in ADP dti-1406 198 4 recent recent ADJ dti-1406 198 5 studies study NOUN dti-1406 198 6 , , PUNCT dti-1406 198 7 it it PRON dti-1406 198 8 was be AUX dti-1406 198 9 shown show VERB dti-1406 198 10 that that SCONJ dti-1406 198 11 7 7 NUM dti-1406 198 12 - - PUNCT dti-1406 198 13 ni ni PROPN dti-1406 198 14 did do AUX dti-1406 198 15 not not PART dti-1406 198 16 have have VERB dti-1406 198 17 a a DET dti-1406 198 18 significant significant ADJ dti-1406 198 19 hypertensive hypertensive ADJ dti-1406 198 20 effect effect NOUN dti-1406 198 21 at at ADP dti-1406 198 22 the the DET dti-1406 198 23 doses dose NOUN dti-1406 198 24 used use VERB dti-1406 198 25 in in ADP dti-1406 198 26 our our PRON dti-1406 198 27 study.26 study.26 ADJ dti-1406 198 28 no no PRON dti-1406 198 29 affects affect VERB dti-1406 198 30 the the DET dti-1406 198 31 release release NOUN dti-1406 198 32 and and CCONJ dti-1406 198 33 reuptake reuptake NOUN dti-1406 198 34 of of ADP dti-1406 198 35 various various ADJ dti-1406 198 36 neurotransmitters,46 neurotransmitters,46 NOUN dti-1406 198 37 which which PRON dti-1406 198 38 results result VERB dti-1406 198 39 in in ADP dti-1406 198 40 the the DET dti-1406 198 41 ltp ltp NOUN dti-1406 198 42 of of ADP dti-1406 198 43 synaptic synaptic ADJ dti-1406 198 44 transmission transmission NOUN dti-1406 198 45 and and CCONJ dti-1406 198 46 the the DET dti-1406 198 47 neuronal neuronal ADJ dti-1406 198 48 basis basis NOUN dti-1406 198 49 of of ADP dti-1406 198 50 memory memory NOUN dti-1406 198 51 formation formation NOUN dti-1406 198 52 . . PUNCT dti-1406 199 1 some some DET dti-1406 199 2 studies study NOUN dti-1406 199 3 have have AUX dti-1406 199 4 reported report VERB dti-1406 199 5 that that SCONJ dti-1406 199 6 nos nos PROPN dti-1406 199 7 inhibitors inhibitor NOUN dti-1406 199 8 do do AUX dti-1406 199 9 not not PART dti-1406 199 10 change change VERB dti-1406 199 11 the the DET dti-1406 199 12 learning learning NOUN dti-1406 199 13 performance performance NOUN dti-1406 199 14 or or CCONJ dti-1406 199 15 memory,47,48 memory,47,48 NOUN dti-1406 199 16 whereas whereas SCONJ dti-1406 199 17 other other ADJ dti-1406 199 18 studies study NOUN dti-1406 199 19 have have AUX dti-1406 199 20 reported report VERB dti-1406 199 21 that that SCONJ dti-1406 199 22 these these DET dti-1406 199 23 drugs drug NOUN dti-1406 199 24 inhibited inhibit VERB dti-1406 199 25 the the DET dti-1406 199 26 retention retention NOUN dti-1406 199 27 trial trial NOUN dti-1406 199 28 of of ADP dti-1406 199 29 the the DET dti-1406 199 30 passive passive ADJ dti-1406 199 31 avoidance avoidance NOUN dti-1406 199 32 test,49,50 test,49,50 NOUN dti-1406 199 33 spatial spatial ADJ dti-1406 199 34 learning learning NOUN dti-1406 199 35 in in ADP dti-1406 199 36 the the DET dti-1406 199 37 water water NOUN dti-1406 199 38 maze maze NOUN dti-1406 199 39 test,51,52 test,51,52 PROPN dti-1406 199 40 or or CCONJ dti-1406 199 41 object object NOUN dti-1406 199 42 recognition14 recognition14 NOUN dti-1406 199 43 in in ADP dti-1406 199 44 the the DET dti-1406 199 45 radial radial ADJ dti-1406 199 46 arm arm NOUN dti-1406 199 47 maze.53 maze.53 NOUN dti-1406 199 48 7 7 NUM dti-1406 199 49 - - PUNCT dti-1406 199 50 ni ni PROPN dti-1406 199 51 has have AUX dti-1406 199 52 been be AUX dti-1406 199 53 shown show VERB dti-1406 199 54 to to PART dti-1406 199 55 impair impair VERB dti-1406 199 56 learning learning NOUN dti-1406 199 57 and and CCONJ dti-1406 199 58 memory memory NOUN dti-1406 199 59 in in ADP dti-1406 199 60 most most ADJ dti-1406 199 61 tests,26,28,37 tests,26,28,37 VERB dti-1406 199 62 and and CCONJ dti-1406 199 63 these these DET dti-1406 199 64 findings finding NOUN dti-1406 199 65 are be AUX dti-1406 199 66 similar similar ADJ dti-1406 199 67 to to ADP dti-1406 199 68 the the DET dti-1406 199 69 results result NOUN dti-1406 199 70 observed observe VERB dti-1406 199 71 in in ADP dti-1406 199 72 our our PRON dti-1406 199 73 study study NOUN dti-1406 199 74 . . PUNCT dti-1406 200 1 our our PRON dti-1406 200 2 study study NOUN dti-1406 200 3 is be AUX dti-1406 200 4 in in ADP dti-1406 200 5 accordance accordance NOUN dti-1406 200 6 with with ADP dti-1406 200 7 the the DET dti-1406 200 8 studies study NOUN dti-1406 200 9 that that PRON dti-1406 200 10 demonstrated demonstrate VERB dti-1406 200 11 the the DET dti-1406 200 12 disturbing disturbing ADJ dti-1406 200 13 effect effect NOUN dti-1406 200 14 of of ADP dti-1406 200 15 nos no NOUN dti-1406 200 16 inhibitors inhibitor NOUN dti-1406 200 17 on on ADP dti-1406 200 18 learning learning NOUN dti-1406 200 19 and and CCONJ dti-1406 200 20 memory memory NOUN dti-1406 200 21 . . PUNCT dti-1406 201 1 the the DET dti-1406 201 2 reversal reversal NOUN dti-1406 201 3 of of ADP dti-1406 201 4 the the DET dti-1406 201 5 7 7 NUM dti-1406 201 6 - - PUNCT dti-1406 201 7 ni ni NOUN dti-1406 201 8 effects effect NOUN dti-1406 201 9 by by ADP dti-1406 201 10 l l NOUN dti-1406 201 11 - - NOUN dti-1406 201 12 arginine arginine NOUN dti-1406 201 13 supports support VERB dti-1406 201 14 the the DET dti-1406 201 15 theory theory NOUN dti-1406 201 16 that that SCONJ dti-1406 201 17 these these DET dti-1406 201 18 effects effect NOUN dti-1406 201 19 are be AUX dti-1406 201 20 specific specific ADJ dti-1406 201 21 to to ADP dti-1406 201 22 nos nos PROPN dti-1406 201 23 . . PUNCT dti-1406 202 1 no no PRON dti-1406 202 2 is be AUX dti-1406 202 3 known know VERB dti-1406 202 4 http://www.la-press.com http://www.la-press.com X dti-1406 202 5 http://www.la-press.com/drug-target-insights-journal-j23 http://www.la-press.com/drug-target-insights-journal-j23 PROPN dti-1406 202 6 7 7 PROPN dti-1406 202 7 - - SYM dti-1406 202 8 ni ni NOUN dti-1406 202 9 and and CCONJ dti-1406 202 10 odq odq NOUN dti-1406 202 11 disturbs disturb VERB dti-1406 202 12 memory memory NOUN dti-1406 202 13 in in ADP dti-1406 202 14 the the DET dti-1406 202 15 elevated elevated ADJ dti-1406 202 16 plus plus CCONJ dti-1406 202 17 maze maze NOUN dti-1406 202 18 7drug 7drug NUM dti-1406 202 19 target target NOUN dti-1406 202 20 insights insight NOUN dti-1406 202 21 2015:9 2015:9 NUM dti-1406 202 22 to to PART dti-1406 202 23 play play VERB dti-1406 202 24 a a DET dti-1406 202 25 role role NOUN dti-1406 202 26 in in ADP dti-1406 202 27 some some DET dti-1406 202 28 forms form NOUN dti-1406 202 29 of of ADP dti-1406 202 30 memory memory NOUN dti-1406 202 31 processing;14,52,53 processing;14,52,53 PROPN dti-1406 202 32 however however ADV dti-1406 202 33 , , PUNCT dti-1406 202 34 the the DET dti-1406 202 35 exact exact ADJ dti-1406 202 36 function function NOUN dti-1406 202 37 is be AUX dti-1406 202 38 not not PART dti-1406 202 39 known know VERB dti-1406 202 40 . . PUNCT dti-1406 203 1 the the DET dti-1406 203 2 activation activation NOUN dti-1406 203 3 of of ADP dti-1406 203 4 the the DET dti-1406 203 5 gc gc PROPN dti-1406 203 6 / / SYM dti-1406 203 7 cgmp cgmp PROPN dti-1406 203 8 / / SYM dti-1406 203 9 protein protein NOUN dti-1406 203 10 kinase kinase PROPN dti-1406 203 11 g g PROPN dti-1406 203 12 ( ( PUNCT dti-1406 203 13 pkg pkg NOUN dti-1406 203 14 ) ) PUNCT dti-1406 203 15 pathway pathway NOUN dti-1406 203 16 causes cause VERB dti-1406 203 17 most most ADJ dti-1406 203 18 no no ADV dti-1406 203 19 - - PUNCT dti-1406 203 20 mediated mediate VERB dti-1406 203 21 physiological physiological ADJ dti-1406 203 22 processes process NOUN dti-1406 203 23 . . PUNCT dti-1406 204 1 edwards edwards PROPN dti-1406 204 2 et et PROPN dti-1406 204 3 al54 al54 PROPN dti-1406 204 4 reported report VERB dti-1406 204 5 that that SCONJ dti-1406 204 6 the the DET dti-1406 204 7 inhibition inhibition NOUN dti-1406 204 8 of of ADP dti-1406 204 9 gc gc PROPN dti-1406 204 10 and and CCONJ dti-1406 204 11 pkg pkg NOUN dti-1406 204 12 impairs impair VERB dti-1406 204 13 retention retention NOUN dti-1406 204 14 for for ADP dti-1406 204 15 the the DET dti-1406 204 16 passive passive ADJ dti-1406 204 17 avoidance avoidance NOUN dti-1406 204 18 task task NOUN dti-1406 204 19 . . PUNCT dti-1406 205 1 kleppsich kleppsich NOUN dti-1406 205 2 et et PROPN dti-1406 206 1 al55 al55 PROPN dti-1406 206 2 reported report VERB dti-1406 206 3 that that SCONJ dti-1406 206 4 pkgs pkg NOUN dti-1406 206 5 are be AUX dti-1406 206 6 not not PART dti-1406 206 7 involved involve VERB dti-1406 206 8 in in ADP dti-1406 206 9 ltp ltp PROPN dti-1406 206 10 in in ADP dti-1406 206 11 mice mouse NOUN dti-1406 206 12 , , PUNCT dti-1406 206 13 but but CCONJ dti-1406 206 14 no no DET dti-1406 206 15 induces induce VERB dti-1406 206 16 ltp ltp NOUN dti-1406 206 17 through through ADP dti-1406 206 18 an an DET dti-1406 206 19 alternative alternative ADJ dti-1406 206 20 cgmp cgmp ADJ dti-1406 206 21 - - ADJ dti-1406 206 22 independent independent ADJ dti-1406 206 23 pathway pathway NOUN dti-1406 206 24 , , PUNCT dti-1406 206 25 possibly possibly ADV dti-1406 206 26 adenosine adenosine VERB dti-1406 206 27 diphosphate diphosphate NOUN dti-1406 206 28 ( ( PUNCT dti-1406 206 29 adp adp PROPN dti-1406 206 30 ) ) PUNCT dti-1406 206 31 ribosylation ribosylation NOUN dti-1406 206 32 . . PUNCT dti-1406 207 1 our our PRON dti-1406 207 2 study study NOUN dti-1406 207 3 supports support VERB dti-1406 207 4 the the DET dti-1406 207 5 role role NOUN dti-1406 207 6 of of ADP dti-1406 207 7 cgmp cgmp NOUN dti-1406 207 8 on on ADP dti-1406 207 9 cognition cognition NOUN dti-1406 207 10 and and CCONJ dti-1406 207 11 the the DET dti-1406 207 12 disruptive disruptive ADJ dti-1406 207 13 effects effect NOUN dti-1406 207 14 of of ADP dti-1406 207 15 odq odq NOUN dti-1406 207 16 on on ADP dti-1406 207 17 learning learning NOUN dti-1406 207 18 and and CCONJ dti-1406 207 19 memory memory NOUN dti-1406 207 20 . . PUNCT dti-1406 208 1 in in ADP dti-1406 208 2 conclusion conclusion NOUN dti-1406 208 3 , , PUNCT dti-1406 208 4 the the DET dti-1406 208 5 present present ADJ dti-1406 208 6 study study NOUN dti-1406 208 7 demonstrates demonstrate VERB dti-1406 208 8 that that SCONJ dti-1406 208 9 both both CCONJ dti-1406 208 10 the the DET dti-1406 208 11 gs gs PROPN dti-1406 208 12 inhibitor inhibitor NOUN dti-1406 208 13 odq odq NOUN dti-1406 208 14 and and CCONJ dti-1406 208 15 the the DET dti-1406 208 16 nos nos PROPN dti-1406 208 17 inhibitor inhibitor NOUN dti-1406 208 18 7 7 NUM dti-1406 208 19 - - PUNCT dti-1406 208 20 ni ni PROPN dti-1406 208 21 disturbed disturb VERB dti-1406 208 22 spatial spatial ADJ dti-1406 208 23 memory memory NOUN dti-1406 208 24 in in ADP dti-1406 208 25 the the DET dti-1406 208 26 mepm mepm NOUN dti-1406 208 27 , , PUNCT dti-1406 208 28 mwm mwm NOUN dti-1406 208 29 , , PUNCT dti-1406 208 30 and and CCONJ dti-1406 208 31 ram ram NOUN dti-1406 208 32 tests test NOUN dti-1406 208 33 . . PUNCT dti-1406 209 1 l l NOUN dti-1406 209 2 - - NOUN dti-1406 209 3 arginine arginine NOUN dti-1406 209 4 , , PUNCT dti-1406 209 5 the the DET dti-1406 209 6 no no DET dti-1406 209 7 precursor precursor NOUN dti-1406 209 8 , , PUNCT dti-1406 209 9 reversed reverse VERB dti-1406 209 10 7 7 NUM dti-1406 209 11 - - PUNCT dti-1406 209 12 ni ni ADJ dti-1406 209 13 - - ADJ dti-1406 209 14 induced induce VERB dti-1406 209 15 changes change NOUN dti-1406 209 16 , , PUNCT dti-1406 209 17 which which PRON dti-1406 209 18 confirms confirm VERB dti-1406 209 19 that that SCONJ dti-1406 209 20 the the DET dti-1406 209 21 effects effect NOUN dti-1406 209 22 of of ADP dti-1406 209 23 7 7 PROPN dti-1406 209 24 - - PUNCT dti-1406 209 25 ni ni PROPN dti-1406 209 26 were be AUX dti-1406 209 27 no no ADV dti-1406 209 28 dependent dependent ADJ dti-1406 209 29 . . PUNCT dti-1406 210 1 our our PRON dti-1406 210 2 findings finding NOUN dti-1406 210 3 suggest suggest VERB dti-1406 210 4 that that SCONJ dti-1406 210 5 the the DET dti-1406 210 6 nnos nno NOUN dti-1406 210 7 / / SYM dti-1406 210 8 sgc sgc PROPN dti-1406 210 9 / / SYM dti-1406 210 10 cgmp cgmp PROPN dti-1406 210 11 pathway pathway NOUN dti-1406 210 12 is be AUX dti-1406 210 13 involved involve VERB dti-1406 210 14 in in ADP dti-1406 210 15 the the DET dti-1406 210 16 pathophysiology pathophysiology NOUN dti-1406 210 17 of of ADP dti-1406 210 18 memory memory NOUN dti-1406 210 19 functions function NOUN dti-1406 210 20 . . PUNCT dti-1406 211 1 author author NOUN dti-1406 211 2 contributions contribution NOUN dti-1406 211 3 conceived conceive VERB dti-1406 211 4 and and CCONJ dti-1406 211 5 designed design VERB dti-1406 211 6 the the DET dti-1406 211 7 experiments experiment NOUN dti-1406 211 8 : : PUNCT dti-1406 211 9 om om PROPN dti-1406 211 10 , , PUNCT dti-1406 211 11 fa fa PROPN dti-1406 211 12 , , PUNCT dti-1406 211 13 ikc ikc PROPN dti-1406 211 14 , , PUNCT dti-1406 211 15 pt pt PROPN dti-1406 211 16 . . PROPN dti-1406 211 17 analyzed analyze VERB dti-1406 211 18 the the DET dti-1406 211 19 data datum NOUN dti-1406 211 20 : : PUNCT dti-1406 211 21 om om PROPN dti-1406 211 22 , , PUNCT dti-1406 211 23 fa fa PROPN dti-1406 211 24 , , PUNCT dti-1406 211 25 ikc ikc PROPN dti-1406 211 26 . . PUNCT dti-1406 212 1 wrote write VERB dti-1406 212 2 the the DET dti-1406 212 3 first first ADJ dti-1406 212 4 draft draft NOUN dti-1406 212 5 of of ADP dti-1406 212 6 the the DET dti-1406 212 7 manuscript manuscript NOUN dti-1406 212 8 : : PUNCT dti-1406 212 9 om om PROPN dti-1406 212 10 , , PUNCT dti-1406 212 11 fa fa PROPN dti-1406 212 12 , , PUNCT dti-1406 212 13 gu gu NOUN dti-1406 212 14 . . PROPN dti-1406 212 15 contributed contribute VERB dti-1406 212 16 to to ADP dti-1406 212 17 the the DET dti-1406 212 18 writing writing NOUN dti-1406 212 19 of of ADP dti-1406 212 20 the the DET dti-1406 212 21 manuscript manuscript NOUN dti-1406 212 22 : : PUNCT dti-1406 212 23 om om PROPN dti-1406 212 24 , , PUNCT dti-1406 212 25 gu gu NOUN dti-1406 212 26 , , PUNCT dti-1406 212 27 fe fe X dti-1406 212 28 . . PROPN dti-1406 212 29 agree agree VERB dti-1406 212 30 with with ADP dti-1406 212 31 manuscript manuscript NOUN dti-1406 212 32 results result NOUN dti-1406 212 33 and and CCONJ dti-1406 212 34 conclusions conclusion NOUN dti-1406 212 35 : : PUNCT dti-1406 212 36 om om PROPN dti-1406 212 37 , , PUNCT dti-1406 212 38 fa fa PROPN dti-1406 212 39 , , PUNCT dti-1406 212 40 ikc ikc PROPN dti-1406 212 41 , , PUNCT dti-1406 212 42 pt pt PROPN dti-1406 212 43 , , PUNCT dti-1406 212 44 gu gu NOUN dti-1406 212 45 , , PUNCT dti-1406 212 46 fe fe X dti-1406 212 47 . . PROPN dti-1406 212 48 jointly jointly ADV dti-1406 212 49 developed develop VERB dti-1406 212 50 the the DET dti-1406 212 51 structure structure NOUN dti-1406 212 52 and and CCONJ dti-1406 212 53 arguments argument NOUN dti-1406 212 54 for for ADP dti-1406 212 55 the the DET dti-1406 212 56 paper paper NOUN dti-1406 212 57 : : PUNCT dti-1406 212 58 fe fe X dti-1406 212 59 , , PUNCT dti-1406 212 60 gu gu PROPN dti-1406 212 61 , , PUNCT dti-1406 212 62 pt pt PROPN dti-1406 212 63 . . PROPN dti-1406 212 64 made make VERB dti-1406 212 65 critical critical ADJ dti-1406 212 66 revisions revision NOUN dti-1406 212 67 and and CCONJ dti-1406 212 68 approved approve VERB dti-1406 212 69 final final ADJ dti-1406 212 70 version version NOUN dti-1406 212 71 : : PUNCT dti-1406 212 72 fa fa PROPN dti-1406 212 73 , , PUNCT dti-1406 212 74 ikc ikc PROPN dti-1406 212 75 , , PUNCT dti-1406 212 76 pt pt X dti-1406 212 77 . . PROPN dti-1406 212 78 all all DET dti-1406 212 79 authors author NOUN dti-1406 212 80 reviewed review VERB dti-1406 212 81 and and CCONJ dti-1406 212 82 approved approve VERB dti-1406 212 83 of of ADP dti-1406 212 84 the the DET dti-1406 212 85 final final ADJ dti-1406 212 86 manuscript manuscript NOUN dti-1406 212 87 . . PUNCT dti-1406 213 1 references reference NOUN dti-1406 213 2 1 1 NUM dti-1406 213 3 . . X dti-1406 214 1 prast prast PROPN dti-1406 214 2 h h NOUN dti-1406 214 3 , , PUNCT dti-1406 214 4 philippu philippu PROPN dti-1406 214 5 a. a. NOUN dti-1406 214 6 nitric nitric ADJ dti-1406 214 7 oxide oxide NOUN dti-1406 214 8 as as ADP dti-1406 214 9 a a DET dti-1406 214 10 modulator modulator NOUN dti-1406 214 11 of of ADP dti-1406 214 12 neuronal neuronal ADJ dti-1406 214 13 function function NOUN dti-1406 214 14 . . PUNCT dti-1406 215 1 prog prog PROPN dti-1406 215 2 neurobiol neurobiol PROPN dti-1406 215 3 . . PUNCT dti-1406 216 1 2001;64:51–56 2001;64:51–56 NUM dti-1406 216 2 . . PUNCT dti-1406 217 1 2 2 NUM dti-1406 217 2 . . X dti-1406 217 3 yildiz yildiz PROPN dti-1406 217 4 f f PROPN dti-1406 217 5 , , PUNCT dti-1406 217 6 erden erden VERB dti-1406 217 7 f f X dti-1406 217 8 , , PUNCT dti-1406 217 9 ulak ulak ADV dti-1406 217 10 g g NOUN dti-1406 217 11 , , PUNCT dti-1406 217 12 utkan utkan PROPN dti-1406 217 13 t t PROPN dti-1406 217 14 , , PUNCT dti-1406 217 15 gacar gacar ADJ dti-1406 217 16 n. n. NOUN dti-1406 217 17 antidepressant antidepressant ADJ dti-1406 217 18 - - PUNCT dti-1406 217 19 like like ADJ dti-1406 217 20 effect effect NOUN dti-1406 217 21 of of ADP dti-1406 217 22 7 7 NUM dti-1406 217 23 - - PUNCT dti-1406 217 24 nitroindazole nitroindazole NOUN dti-1406 217 25 in in ADP dti-1406 217 26 the the DET dti-1406 217 27 forced force VERB dti-1406 217 28 swimming swimming NOUN dti-1406 217 29 test test NOUN dti-1406 217 30 in in ADP dti-1406 217 31 rats rat NOUN dti-1406 217 32 . . PUNCT dti-1406 218 1 psychopharmacology psychopharmacology NOUN dti-1406 218 2 . . PUNCT dti-1406 219 1 2000 2000 NUM dti-1406 219 2 ; ; PUNCT dti-1406 219 3 149:41–44 149:41–44 NUM dti-1406 219 4 . . PROPN dti-1406 219 5 3 3 NUM dti-1406 219 6 . . X dti-1406 219 7 yildiz yildiz PROPN dti-1406 219 8 f f PROPN dti-1406 219 9 , , PUNCT dti-1406 219 10 ulak ulak ADV dti-1406 219 11 g g NOUN dti-1406 219 12 , , PUNCT dti-1406 219 13 erden erden VERB dti-1406 219 14 f f PROPN dti-1406 219 15 , , PUNCT dti-1406 219 16 gacar gacar ADJ dti-1406 219 17 n. n. NOUN dti-1406 219 18 anxiolytic anxiolytic ADJ dti-1406 219 19 - - PUNCT dti-1406 219 20 like like ADJ dti-1406 219 21 effects effect NOUN dti-1406 219 22 of of ADP dti-1406 219 23 7 7 NUM dti-1406 219 24 - - PUNCT dti-1406 219 25 nitroindazole nitroindazole NOUN dti-1406 219 26 in in ADP dti-1406 219 27 the the DET dti-1406 219 28 rat rat NOUN dti-1406 219 29 plus plus CCONJ dti-1406 219 30 - - PUNCT dti-1406 219 31 maze maze NOUN dti-1406 219 32 test test NOUN dti-1406 219 33 . . PUNCT dti-1406 220 1 pharmacol pharmacol PROPN dti-1406 220 2 biochem biochem PROPN dti-1406 220 3 behav behav NOUN dti-1406 220 4 . . PUNCT dti-1406 221 1 2000;65:199–202 2000;65:199–202 NOUN dti-1406 221 2 . . PUNCT dti-1406 222 1 4 4 X dti-1406 222 2 . . X dti-1406 222 3 trainor trainor PROPN dti-1406 222 4 bc bc PROPN dti-1406 222 5 , , PUNCT dti-1406 222 6 workman workman NOUN dti-1406 222 7 jl jl PROPN dti-1406 222 8 , , PUNCT dti-1406 222 9 jessen jessen PROPN dti-1406 222 10 r r PROPN dti-1406 222 11 , , PUNCT dti-1406 222 12 nelson nelson PROPN dti-1406 222 13 rj rj PROPN dti-1406 222 14 . . PUNCT dti-1406 223 1 impaired impair VERB dti-1406 223 2 nitric nitric ADJ dti-1406 223 3 oxide oxide NOUN dti-1406 223 4 synthase synthase NOUN dti-1406 223 5 signaling signal VERB dti-1406 223 6 dissociates dissociate NOUN dti-1406 223 7 social social ADJ dti-1406 223 8 investigation investigation NOUN dti-1406 223 9 and and CCONJ dti-1406 223 10 aggression aggression NOUN dti-1406 223 11 . . PUNCT dti-1406 224 1 behav behav PROPN dti-1406 224 2 neurosci neurosci PROPN dti-1406 224 3 . . PUNCT dti-1406 225 1 2007 2007 NUM dti-1406 225 2 ; ; PUNCT dti-1406 225 3 121:362–369 121:362–369 NUM dti-1406 225 4 . . PUNCT dti-1406 226 1 5 5 NUM dti-1406 226 2 . . X dti-1406 226 3 susswein susswein PROPN dti-1406 226 4 aj aj PROPN dti-1406 226 5 , , PUNCT dti-1406 226 6 katzoff katzoff PROPN dti-1406 226 7 a a PRON dti-1406 226 8 , , PUNCT dti-1406 226 9 miller miller PROPN dti-1406 226 10 n n CCONJ dti-1406 226 11 , , PUNCT dti-1406 226 12 hurwitz hurwitz PROPN dti-1406 226 13 i. i. PROPN dti-1406 226 14 nitric nitric ADJ dti-1406 226 15 oxide oxide NOUN dti-1406 226 16 and and CCONJ dti-1406 226 17 memory memory NOUN dti-1406 226 18 . . PUNCT dti-1406 226 19 neuroscientist neuroscientist NOUN dti-1406 226 20 . . PUNCT dti-1406 227 1 2004;10:153–162 2004;10:153–162 NUM dti-1406 227 2 . . PUNCT dti-1406 228 1 6 6 NUM dti-1406 228 2 . . X dti-1406 228 3 barnstable barnstable PROPN dti-1406 228 4 cj cj PROPN dti-1406 228 5 , , PUNCT dti-1406 228 6 wei wei PROPN dti-1406 228 7 jy jy PROPN dti-1406 228 8 , , PUNCT dti-1406 228 9 han han PROPN dti-1406 228 10 mh mh PROPN dti-1406 228 11 . . PUNCT dti-1406 229 1 modulation modulation NOUN dti-1406 229 2 of of ADP dti-1406 229 3 synaptic synaptic ADJ dti-1406 229 4 function function NOUN dti-1406 229 5 by by ADP dti-1406 229 6 cgmp cgmp PROPN dti-1406 229 7 and and CCONJ dti-1406 229 8 gmp gmp PROPN dti-1406 229 9 - - PUNCT dti-1406 229 10 gated gate VERB dti-1406 229 11 cation cation NOUN dti-1406 229 12 channels channel NOUN dti-1406 229 13 . . PUNCT dti-1406 230 1 neurochem neurochem PROPN dti-1406 230 2 int int NOUN dti-1406 230 3 . . PUNCT dti-1406 231 1 2004;45:875–884 2004;45:875–884 NUM dti-1406 231 2 . . PUNCT dti-1406 232 1 7 7 X dti-1406 232 2 . . X dti-1406 232 3 chien chien PROPN dti-1406 232 4 wl wl PROPN dti-1406 232 5 , , PUNCT dti-1406 232 6 liang liang PROPN dti-1406 232 7 kc kc PROPN dti-1406 232 8 , , PUNCT dti-1406 232 9 teng teng PROPN dti-1406 232 10 cm cm PROPN dti-1406 232 11 , , PUNCT dti-1406 232 12 kuo kuo PROPN dti-1406 232 13 sc sc PROPN dti-1406 232 14 , , PUNCT dti-1406 232 15 lee lee PROPN dti-1406 232 16 fy fy PROPN dti-1406 232 17 , , PUNCT dti-1406 232 18 fu fu PROPN dti-1406 232 19 wm wm PROPN dti-1406 232 20 . . PROPN dti-1406 232 21 enhancement enhancement NOUN dti-1406 232 22 of of ADP dti-1406 232 23 learning learn VERB dti-1406 232 24 behaviour behaviour NOUN dti-1406 232 25 by by ADP dti-1406 232 26 a a DET dti-1406 232 27 potent potent ADJ dti-1406 232 28 nitric nitric ADJ dti-1406 232 29 oxide oxide NOUN dti-1406 232 30 - - PUNCT dti-1406 232 31 guanylate guanylate NOUN dti-1406 232 32 cyclase cyclase NOUN dti-1406 232 33 activator activator NOUN dti-1406 232 34 yc-1 yc-1 NOUN dti-1406 232 35 . . PUNCT dti-1406 233 1 eur eur PROPN dti-1406 233 2 j j PROPN dti-1406 233 3 neurosci neurosci PROPN dti-1406 233 4 . . PUNCT dti-1406 234 1 2005;21:1679–1688 2005;21:1679–1688 NUM dti-1406 234 2 . . PUNCT dti-1406 235 1 8 8 NUM dti-1406 235 2 . . X dti-1406 235 3 chien chien PROPN dti-1406 235 4 wl wl PROPN dti-1406 235 5 , , PUNCT dti-1406 235 6 liang liang PROPN dti-1406 235 7 kc kc PROPN dti-1406 235 8 , , PUNCT dti-1406 235 9 fu fu PROPN dti-1406 235 10 wm wm PROPN dti-1406 235 11 . . PROPN dti-1406 235 12 enhancement enhancement NOUN dti-1406 235 13 of of ADP dti-1406 235 14 active active ADJ dti-1406 235 15 shuttle shuttle NOUN dti-1406 235 16 avoidance avoidance NOUN dti-1406 235 17 response response NOUN dti-1406 235 18 by by ADP dti-1406 235 19 the the DET dti-1406 235 20 no no DET dti-1406 235 21 - - PUNCT dti-1406 235 22 cgmp cgmp ADJ dti-1406 235 23 - - PUNCT dti-1406 235 24 pkg pkg NOUN dti-1406 235 25 activator activator NOUN dti-1406 235 26 yc-1 yc-1 NOUN dti-1406 235 27 . . PUNCT dti-1406 236 1 eur eur PROPN dti-1406 236 2 j j PROPN dti-1406 236 3 pharmacol pharmacol PROPN dti-1406 236 4 . . PUNCT dti-1406 237 1 2008;590 2008;590 NUM dti-1406 237 2 : : PUNCT dti-1406 238 1 233–240 233–240 NUM dti-1406 238 2 . . NOUN dti-1406 238 3 9 9 NUM dti-1406 238 4 . . X dti-1406 238 5 zhuo zhuo PROPN dti-1406 238 6 m m PROPN dti-1406 238 7 , , PUNCT dti-1406 238 8 hu hu PROPN dti-1406 238 9 y y PROPN dti-1406 238 10 , , PUNCT dti-1406 238 11 schultz schultz PROPN dti-1406 238 12 c c PROPN dti-1406 238 13 , , PUNCT dti-1406 238 14 kandel kandel PROPN dti-1406 238 15 er er INTJ dti-1406 238 16 , , PUNCT dti-1406 238 17 hawkins hawkins PROPN dti-1406 238 18 rd rd PROPN dti-1406 238 19 . . PUNCT dti-1406 239 1 role role NOUN dti-1406 239 2 of of ADP dti-1406 239 3 guanylyl guanylyl ADJ dti-1406 239 4 cyclase cyclase NOUN dti-1406 239 5 and and CCONJ dti-1406 239 6 cgmpdependent cgmpdependent VERB dti-1406 239 7 protein protein NOUN dti-1406 239 8 kinases kinase NOUN dti-1406 239 9 in in ADP dti-1406 239 10 long long ADJ dti-1406 239 11 - - PUNCT dti-1406 239 12 term term NOUN dti-1406 239 13 potentiation potentiation NOUN dti-1406 239 14 . . PUNCT dti-1406 240 1 nature nature NOUN dti-1406 240 2 . . PUNCT dti-1406 241 1 1994 1994 NUM dti-1406 241 2 ; ; PUNCT dti-1406 242 1 368:635–639 368:635–639 NUM dti-1406 242 2 . . PUNCT dti-1406 243 1 10 10 NUM dti-1406 243 2 . . PUNCT dti-1406 243 3 garthwaite garthwaite PROPN dti-1406 243 4 j. j. PROPN dti-1406 243 5 glutamate glutamate PROPN dti-1406 243 6 , , PUNCT dti-1406 243 7 nitric nitric ADJ dti-1406 243 8 oxide oxide NOUN dti-1406 243 9 and and CCONJ dti-1406 243 10 cell cell NOUN dti-1406 243 11 – – PUNCT dti-1406 243 12 cell cell NOUN dti-1406 243 13 signalling signal VERB dti-1406 243 14 in in ADP dti-1406 243 15 the the DET dti-1406 243 16 nervous nervous ADJ dti-1406 243 17 system system NOUN dti-1406 243 18 . . PUNCT dti-1406 244 1 trends trend NOUN dti-1406 244 2 neurosci neurosci PROPN dti-1406 244 3 . . PUNCT dti-1406 245 1 1991;14:60–67 1991;14:60–67 NUM dti-1406 245 2 . . PUNCT dti-1406 246 1 11 11 NUM dti-1406 246 2 . . PUNCT dti-1406 247 1 southam southam PROPN dti-1406 247 2 e e PROPN dti-1406 247 3 , , PUNCT dti-1406 247 4 garthwaite garthwaite NOUN dti-1406 247 5 j. j. PROPN dti-1406 247 6 the the DET dti-1406 247 7 nitric nitric ADJ dti-1406 247 8 oxide oxide NOUN dti-1406 247 9 - - PUNCT dti-1406 247 10 cyclic cyclic NOUN dti-1406 247 11 gmp gmp NOUN dti-1406 247 12 signalling signal VERB dti-1406 247 13 pathway pathway NOUN dti-1406 247 14 in in ADP dti-1406 247 15 rat rat NOUN dti-1406 247 16 brain brain NOUN dti-1406 247 17 . . PUNCT dti-1406 248 1 neuropharmacology neuropharmacology NOUN dti-1406 248 2 . . PUNCT dti-1406 249 1 1993;32:1267–1277 1993;32:1267–1277 NOUN dti-1406 249 2 . . PUNCT dti-1406 250 1 12 12 NUM dti-1406 250 2 . . PUNCT dti-1406 251 1 arancio arancio PROPN dti-1406 251 2 o o PROPN dti-1406 251 3 , , PUNCT dti-1406 251 4 kandel kandel PROPN dti-1406 251 5 er er INTJ dti-1406 251 6 , , PUNCT dti-1406 251 7 hawkins hawkins PROPN dti-1406 251 8 rd rd PROPN dti-1406 251 9 . . PUNCT dti-1406 252 1 activity activity NOUN dti-1406 252 2 - - PUNCT dti-1406 252 3 dependent dependent ADJ dti-1406 252 4 long long ADJ dti-1406 252 5 - - PUNCT dti-1406 252 6 term term NOUN dti-1406 252 7 enhancement enhancement NOUN dti-1406 252 8 of of ADP dti-1406 252 9 transmitter transmitter NOUN dti-1406 252 10 release release NOUN dti-1406 252 11 by by ADP dti-1406 252 12 presynaptic presynaptic ADJ dti-1406 252 13 3x 3x NUM dti-1406 252 14 , , PUNCT dti-1406 252 15 5xcyclic 5xcyclic PROPN dti-1406 252 16 - - PUNCT dti-1406 252 17 gmp gmp PROPN dti-1406 252 18 in in ADP dti-1406 252 19 cultured cultured ADJ dti-1406 252 20 hippocampal hippocampal ADJ dti-1406 252 21 neurons neuron NOUN dti-1406 252 22 . . PUNCT dti-1406 253 1 nature nature NOUN dti-1406 253 2 . . PUNCT dti-1406 254 1 1995;376:74–80 1995;376:74–80 NUM dti-1406 254 2 . . NOUN dti-1406 254 3 13 13 NUM dti-1406 254 4 . . PUNCT dti-1406 255 1 boulton boulton PROPN dti-1406 255 2 cl cl PROPN dti-1406 255 3 , , PUNCT dti-1406 255 4 southam southam PROPN dti-1406 255 5 e e PROPN dti-1406 255 6 , , PUNCT dti-1406 255 7 garthwaite garthwaite ADJ dti-1406 255 8 j. j. PROPN dti-1406 255 9 nitric nitric ADJ dti-1406 255 10 oxide oxide NOUN dti-1406 255 11 - - PUNCT dti-1406 255 12 dependent dependent ADJ dti-1406 255 13 long long ADJ dti-1406 255 14 - - PUNCT dti-1406 255 15 term term NOUN dti-1406 255 16 potentiation potentiation NOUN dti-1406 255 17 is be AUX dti-1406 255 18 blocked block VERB dti-1406 255 19 by by ADP dti-1406 255 20 a a DET dti-1406 255 21 specific specific ADJ dti-1406 255 22 inhibitor inhibitor NOUN dti-1406 255 23 of of ADP dti-1406 255 24 soluble soluble ADJ dti-1406 255 25 guanylyl guanylyl ADJ dti-1406 255 26 cyclase cyclase NOUN dti-1406 255 27 . . PUNCT dti-1406 256 1 neuroscience neuroscience NOUN dti-1406 256 2 . . PUNCT dti-1406 257 1 1995;69:699–703 1995;69:699–703 NUM dti-1406 257 2 . . PROPN dti-1406 258 1 14 14 NUM dti-1406 258 2 . . PUNCT dti-1406 259 1 prickaerts prickaerts PROPN dti-1406 259 2 j j PROPN dti-1406 259 3 , , PUNCT dti-1406 259 4 steinbusch steinbusch VERB dti-1406 259 5 hw hw PROPN dti-1406 259 6 , , PUNCT dti-1406 259 7 smits smit VERB dti-1406 259 8 jf jf PROPN dti-1406 259 9 , , PUNCT dti-1406 259 10 vente vente PROPN dti-1406 259 11 j. j. PROPN dti-1406 259 12 possible possible ADJ dti-1406 259 13 role role NOUN dti-1406 259 14 of of ADP dti-1406 259 15 nitric nitric ADJ dti-1406 259 16 oxidecyclic oxidecyclic ADJ dti-1406 259 17 gmp gmp PROPN dti-1406 259 18 pathway pathway NOUN dti-1406 259 19 in in ADP dti-1406 259 20 object object NOUN dti-1406 259 21 recognition recognition NOUN dti-1406 259 22 memory memory NOUN dti-1406 259 23 : : PUNCT dti-1406 259 24 effects effect NOUN dti-1406 259 25 of of ADP dti-1406 259 26 7 7 NUM dti-1406 259 27 - - PUNCT dti-1406 259 28 nitroindazole nitroindazole NOUN dti-1406 259 29 and and CCONJ dti-1406 259 30 zaprinast zaprinast NOUN dti-1406 259 31 . . PUNCT dti-1406 260 1 eur eur PROPN dti-1406 260 2 j j PROPN dti-1406 260 3 pharmacol pharmacol PROPN dti-1406 260 4 . . PUNCT dti-1406 261 1 1997;33:125–136 1997;33:125–136 NUM dti-1406 261 2 . . PUNCT dti-1406 262 1 15 15 NUM dti-1406 262 2 . . PUNCT dti-1406 263 1 meyer meyer PROPN dti-1406 263 2 cr cr PROPN dti-1406 263 3 , , PUNCT dti-1406 263 4 spangler spangler PROPN dti-1406 263 5 el el PROPN dti-1406 263 6 , , PUNCT dti-1406 263 7 patel patel PROPN dti-1406 263 8 n n CCONJ dti-1406 263 9 , , PUNCT dti-1406 263 10 london london PROPN dti-1406 263 11 ed ed PROPN dti-1406 263 12 , , PUNCT dti-1406 263 13 ingram ingram PROPN dti-1406 263 14 dk dk PROPN dti-1406 263 15 . . PROPN dti-1406 263 16 impaired impaired ADJ dti-1406 263 17 learning learning NOUN dti-1406 263 18 in in ADP dti-1406 263 19 rats rat NOUN dti-1406 263 20 in in ADP dti-1406 263 21 a a DET dti-1406 263 22 14 14 NUM dti-1406 263 23 - - PUNCT dti-1406 263 24 unit unit NOUN dti-1406 263 25 t t PROPN dti-1406 263 26 - - PUNCT dti-1406 263 27 maze maze NOUN dti-1406 263 28 by by ADP dti-1406 263 29 7 7 NUM dti-1406 263 30 - - PUNCT dti-1406 263 31 nitroindazole nitroindazole NOUN dti-1406 263 32 , , PUNCT dti-1406 263 33 a a DET dti-1406 263 34 neuronal neuronal ADJ dti-1406 263 35 nitric nitric ADJ dti-1406 263 36 oxide oxide NOUN dti-1406 263 37 synthase synthase NOUN dti-1406 263 38 inhibitor inhibitor NOUN dti-1406 263 39 , , PUNCT dti-1406 263 40 is be AUX dti-1406 263 41 attenuated attenuate VERB dti-1406 263 42 by by ADP dti-1406 263 43 the the DET dti-1406 263 44 nitric nitric ADJ dti-1406 263 45 oxide oxide NOUN dti-1406 263 46 donor donor NOUN dti-1406 263 47 , , PUNCT dti-1406 263 48 molsidomine molsidomine NOUN dti-1406 263 49 . . PUNCT dti-1406 264 1 eur eur PROPN dti-1406 264 2 j j PROPN dti-1406 264 3 pharmacol pharmacol PROPN dti-1406 264 4 . . PUNCT dti-1406 265 1 1998;341:17–22 1998;341:17–22 NUM dti-1406 265 2 . . PROPN dti-1406 265 3 16 16 NUM dti-1406 265 4 . . PUNCT dti-1406 266 1 knepper knepper PROPN dti-1406 266 2 br br PROPN dti-1406 266 3 , , PUNCT dti-1406 266 4 kurylo kurylo PROPN dti-1406 266 5 dd dd PROPN dti-1406 266 6 . . PUNCT dti-1406 266 7 effects effect NOUN dti-1406 266 8 of of ADP dti-1406 266 9 nitric nitric ADJ dti-1406 266 10 oxide oxide NOUN dti-1406 266 11 synthase synthase NOUN dti-1406 266 12 inhibitor inhibitor NOUN dti-1406 266 13 ng ng PROPN dti-1406 266 14 - - PUNCT dti-1406 266 15 nitro nitro NOUN dti-1406 266 16 - - PUNCT dti-1406 266 17 larginine larginine ADJ dti-1406 266 18 methyl methyl NOUN dti-1406 266 19 ester ester NOUN dti-1406 266 20 on on ADP dti-1406 266 21 spatial spatial ADJ dti-1406 266 22 and and CCONJ dti-1406 266 23 cued cued ADJ dti-1406 266 24 learning learning NOUN dti-1406 266 25 . . PUNCT dti-1406 267 1 neuroscience neuroscience NOUN dti-1406 267 2 . . PUNCT dti-1406 268 1 1998;83:837–841 1998;83:837–841 PROPN dti-1406 268 2 . . PUNCT dti-1406 269 1 17 17 NUM dti-1406 269 2 . . PUNCT dti-1406 270 1 blokland blokland PROPN dti-1406 270 2 a a DET dti-1406 270 3 , , PUNCT dti-1406 270 4 de de PROPN dti-1406 270 5 vente vente PROPN dti-1406 270 6 j j PROPN dti-1406 270 7 , , PUNCT dti-1406 270 8 prickaerts prickaerts PROPN dti-1406 270 9 j j PROPN dti-1406 270 10 , , PUNCT dti-1406 270 11 honig honig PROPN dti-1406 270 12 w w PROPN dti-1406 270 13 , , PUNCT dti-1406 270 14 markerink markerink ADJ dti-1406 270 15 - - PUNCT dti-1406 270 16 van van PROPN dti-1406 270 17 ittersum ittersum PROPN dti-1406 270 18 m m PROPN dti-1406 270 19 , , PUNCT dti-1406 270 20 steinsbuch steinsbuch PROPN dti-1406 270 21 h. h. PROPN dti-1406 270 22 local local ADJ dti-1406 270 23 inhibition inhibition NOUN dti-1406 270 24 of of ADP dti-1406 270 25 hippocampal hippocampal ADJ dti-1406 270 26 nitric nitric ADJ dti-1406 270 27 oxide oxide NOUN dti-1406 270 28 synthase synthase NOUN dti-1406 270 29 does do AUX dti-1406 270 30 not not PART dti-1406 270 31 impair impair VERB dti-1406 270 32 place place NOUN dti-1406 270 33 learning learn VERB dti-1406 270 34 in in ADP dti-1406 270 35 the the DET dti-1406 270 36 morris morris PROPN dti-1406 270 37 water water NOUN dti-1406 270 38 escape escape NOUN dti-1406 270 39 task task NOUN dti-1406 270 40 in in ADP dti-1406 270 41 the the DET dti-1406 270 42 rat rat NOUN dti-1406 270 43 . . PROPN dti-1406 270 44 eur eur PROPN dti-1406 270 45 j j PROPN dti-1406 270 46 neurosci neurosci PROPN dti-1406 270 47 . . PUNCT dti-1406 270 48 1999 1999 NUM dti-1406 270 49 ; ; PUNCT dti-1406 271 1 11:223–232 11:223–232 NUM dti-1406 271 2 . . PROPN dti-1406 272 1 18 18 NUM dti-1406 272 2 . . PUNCT dti-1406 273 1 estall estall PROPN dti-1406 273 2 lb lb PROPN dti-1406 273 3 , , PUNCT dti-1406 273 4 grant grant NOUN dti-1406 273 5 sj sj PROPN dti-1406 273 6 , , PUNCT dti-1406 273 7 cicala cicala PROPN dti-1406 273 8 ga ga PROPN dti-1406 273 9 . . PROPN dti-1406 273 10 inhibition inhibition NOUN dti-1406 273 11 of of ADP dti-1406 273 12 nitric nitric ADJ dti-1406 273 13 oxide oxide NOUN dti-1406 273 14 ( ( PUNCT dti-1406 273 15 no no NOUN dti-1406 273 16 ) ) PUNCT dti-1406 273 17 production production NOUN dti-1406 273 18 selectively selectively ADV dti-1406 273 19 impairs impair VERB dti-1406 273 20 learning learning NOUN dti-1406 273 21 and and CCONJ dti-1406 273 22 memory memory NOUN dti-1406 273 23 in in ADP dti-1406 273 24 the the DET dti-1406 273 25 rat rat NOUN dti-1406 273 26 . . PROPN dti-1406 273 27 pharmacol pharmacol PROPN dti-1406 273 28 biochem biochem PROPN dti-1406 273 29 behav behav NOUN dti-1406 273 30 . . PUNCT dti-1406 273 31 1993 1993 NUM dti-1406 273 32 ; ; PUNCT dti-1406 274 1 46:959–962 46:959–962 NUM dti-1406 274 2 . . PUNCT dti-1406 275 1 19 19 NUM dti-1406 275 2 . . PUNCT dti-1406 275 3 yamada yamada PROPN dti-1406 275 4 k k PROPN dti-1406 275 5 , , PUNCT dti-1406 275 6 noda noda PROPN dti-1406 275 7 y y PROPN dti-1406 275 8 , , PUNCT dti-1406 275 9 nakayama nakayama PROPN dti-1406 275 10 s s PROPN dti-1406 275 11 , , PUNCT dti-1406 275 12 et et PROPN dti-1406 275 13 al al PROPN dti-1406 275 14 . . PROPN dti-1406 275 15 role role NOUN dti-1406 275 16 of of ADP dti-1406 275 17 nitric nitric ADJ dti-1406 275 18 oxide oxide NOUN dti-1406 275 19 in in ADP dti-1406 275 20 learning learning NOUN dti-1406 275 21 and and CCONJ dti-1406 275 22 memory memory NOUN dti-1406 275 23 and and CCONJ dti-1406 275 24 in in ADP dti-1406 275 25 monoamine monoamine ADJ dti-1406 275 26 metabolism metabolism NOUN dti-1406 275 27 in in ADP dti-1406 275 28 the the DET dti-1406 275 29 rat rat NOUN dti-1406 275 30 brain brain NOUN dti-1406 275 31 . . PUNCT dti-1406 276 1 br br PROPN dti-1406 276 2 j j PROPN dti-1406 276 3 pharmacol pharmacol PROPN dti-1406 276 4 . . PUNCT dti-1406 277 1 1995;115 1995;115 NUM dti-1406 277 2 : : PUNCT dti-1406 278 1 852–858 852–858 NUM dti-1406 278 2 . . PUNCT dti-1406 279 1 20 20 NUM dti-1406 279 2 . . PUNCT dti-1406 280 1 bannerman bannerman PROPN dti-1406 280 2 dm dm PROPN dti-1406 280 3 , , PUNCT dti-1406 280 4 chapman chapman PROPN dti-1406 280 5 pf pf PROPN dti-1406 280 6 , , PUNCT dti-1406 280 7 kelly kelly PROPN dti-1406 280 8 pa pa PROPN dti-1406 280 9 , , PUNCT dti-1406 280 10 butcher butcher PROPN dti-1406 280 11 sp sp PROPN dti-1406 280 12 , , PUNCT dti-1406 280 13 morris morris PROPN dti-1406 280 14 rg rg PROPN dti-1406 280 15 . . PROPN dti-1406 280 16 inhibition inhibition NOUN dti-1406 280 17 of of ADP dti-1406 280 18 nitric nitric ADJ dti-1406 280 19 oxide oxide NOUN dti-1406 280 20 synthase synthase NOUN dti-1406 280 21 does do AUX dti-1406 280 22 not not PART dti-1406 280 23 impair impair VERB dti-1406 280 24 spatial spatial ADJ dti-1406 280 25 learning learning NOUN dti-1406 280 26 . . PUNCT dti-1406 281 1 j j PROPN dti-1406 281 2 neurosci neurosci PROPN dti-1406 281 3 . . PUNCT dti-1406 282 1 1994;14 1994;14 NUM dti-1406 282 2 : : PUNCT dti-1406 282 3 7404–7414 7404–7414 NUM dti-1406 282 4 . . NOUN dti-1406 282 5 21 21 NUM dti-1406 282 6 . . PUNCT dti-1406 283 1 bon bon PROPN dti-1406 283 2 c c PROPN dti-1406 283 3 , , PUNCT dti-1406 283 4 böhme böhme PROPN dti-1406 283 5 ga ga PROPN dti-1406 283 6 , , PUNCT dti-1406 283 7 doble doble PROPN dti-1406 283 8 a a PRON dti-1406 283 9 , , PUNCT dti-1406 283 10 stutzmann stutzmann PROPN dti-1406 283 11 j j PROPN dti-1406 283 12 - - PROPN dti-1406 283 13 m m PROPN dti-1406 283 14 , , PUNCT dti-1406 283 15 blanchard blanchard PROPN dti-1406 283 16 j j PROPN dti-1406 283 17 - - PROPN dti-1406 283 18 c. c. PROPN dti-1406 283 19 a a DET dti-1406 283 20 role role NOUN dti-1406 283 21 for for ADP dti-1406 283 22 nitric nitric ADJ dti-1406 283 23 oxide oxide NOUN dti-1406 283 24 in in ADP dti-1406 283 25 long long ADJ dti-1406 283 26 - - PUNCT dti-1406 283 27 term term NOUN dti-1406 283 28 potentiation potentiation NOUN dti-1406 283 29 . . PUNCT dti-1406 284 1 eur eur PROPN dti-1406 284 2 j j PROPN dti-1406 284 3 pharmacol pharmacol PROPN dti-1406 284 4 . . PUNCT dti-1406 285 1 1992;4:420–424 1992;4:420–424 NUM dti-1406 285 2 . . PROPN dti-1406 285 3 22 22 NUM dti-1406 285 4 . . PUNCT dti-1406 286 1 doyle doyle PROPN dti-1406 286 2 c c PROPN dti-1406 286 3 , , PUNCT dti-1406 286 4 hölscher hölscher NOUN dti-1406 286 5 c c NOUN dti-1406 286 6 , , PUNCT dti-1406 286 7 rowan rowan PROPN dti-1406 286 8 mj mj PROPN dti-1406 286 9 , , PUNCT dti-1406 286 10 anwyl anwyl PROPN dti-1406 286 11 r. r. VERB dti-1406 286 12 the the DET dti-1406 286 13 selective selective ADJ dti-1406 286 14 neuronal neuronal ADJ dti-1406 286 15 no no DET dti-1406 286 16 synthase synthase NOUN dti-1406 286 17 inhibitor inhibitor NOUN dti-1406 286 18 7 7 NUM dti-1406 286 19 - - PUNCT dti-1406 286 20 nitro nitro NOUN dti-1406 286 21 - - PUNCT dti-1406 286 22 indazole indazole NOUN dti-1406 286 23 blocks block NOUN dti-1406 286 24 both both DET dti-1406 286 25 long long ADJ dti-1406 286 26 - - PUNCT dti-1406 286 27 term term NOUN dti-1406 286 28 potentiation potentiation NOUN dti-1406 286 29 and and CCONJ dti-1406 286 30 depotentiation depotentiation NOUN dti-1406 286 31 of of ADP dti-1406 286 32 field field NOUN dti-1406 286 33 epsps epsp NOUN dti-1406 286 34 in in ADP dti-1406 286 35 rat rat PROPN dti-1406 286 36 hippocampal hippocampal PROPN dti-1406 286 37 ca1 ca1 PROPN dti-1406 286 38 in in ADP dti-1406 286 39 vivo vivo NOUN dti-1406 286 40 . . PUNCT dti-1406 287 1 j j PROPN dti-1406 287 2 neurosci neurosci PROPN dti-1406 287 3 . . PUNCT dti-1406 288 1 1996;16:418–426 1996;16:418–426 NUM dti-1406 288 2 . . PUNCT dti-1406 289 1 23 23 NUM dti-1406 289 2 . . PUNCT dti-1406 290 1 southam southam PROPN dti-1406 290 2 e e PROPN dti-1406 290 3 , , PUNCT dti-1406 290 4 charles charles PROPN dti-1406 290 5 sl sl PROPN dti-1406 290 6 , , PUNCT dti-1406 290 7 garthwaite garthwaite NOUN dti-1406 290 8 j. j. PROPN dti-1406 290 9 the the DET dti-1406 290 10 nitric nitric ADJ dti-1406 290 11 oxide oxide NOUN dti-1406 290 12 - - PUNCT dti-1406 290 13 cyclic cyclic NOUN dti-1406 290 14 gmp gmp NOUN dti-1406 290 15 pathway pathway NOUN dti-1406 290 16 and and CCONJ dti-1406 290 17 synaptic synaptic ADJ dti-1406 290 18 plasticity plasticity NOUN dti-1406 290 19 in in ADP dti-1406 290 20 the the DET dti-1406 290 21 rat rat NOUN dti-1406 290 22 superior superior ADJ dti-1406 290 23 cervical cervical ADJ dti-1406 290 24 ganglion ganglion NOUN dti-1406 290 25 . . PUNCT dti-1406 291 1 br br PROPN dti-1406 291 2 j j PROPN dti-1406 291 3 pharmacol pharmacol PROPN dti-1406 291 4 . . PUNCT dti-1406 291 5 1996 1996 NUM dti-1406 291 6 ; ; PUNCT dti-1406 291 7 119:527–532 119:527–532 NUM dti-1406 291 8 . . PUNCT dti-1406 292 1 24 24 NUM dti-1406 292 2 . . PUNCT dti-1406 293 1 cummings cummings PROPN dti-1406 293 2 ja ja PROPN dti-1406 293 3 , , PUNCT dti-1406 293 4 nicola nicola PROPN dti-1406 293 5 sm sm PROPN dti-1406 293 6 , , PUNCT dti-1406 293 7 malenka malenka PROPN dti-1406 293 8 rc rc PROPN dti-1406 293 9 . . PROPN dti-1406 293 10 induction induction NOUN dti-1406 293 11 in in ADP dti-1406 293 12 the the DET dti-1406 293 13 rat rat NOUN dti-1406 293 14 hippocampus hippocampus NOUN dti-1406 293 15 of of ADP dti-1406 293 16 long long ADJ dti-1406 293 17 - - PUNCT dti-1406 293 18 term term NOUN dti-1406 293 19 potentiation potentiation NOUN dti-1406 293 20 ( ( PUNCT dti-1406 293 21 ltp ltp NOUN dti-1406 293 22 ) ) PUNCT dti-1406 293 23 and and CCONJ dti-1406 293 24 long long ADJ dti-1406 293 25 - - PUNCT dti-1406 293 26 term term NOUN dti-1406 293 27 depression depression NOUN dti-1406 293 28 ( ( PUNCT dti-1406 293 29 ltd ltd ADJ dti-1406 293 30 ) ) PUNCT dti-1406 293 31 in in ADP dti-1406 293 32 the the DET dti-1406 293 33 presence presence NOUN dti-1406 293 34 of of ADP dti-1406 293 35 a a DET dti-1406 293 36 nitric nitric ADJ dti-1406 293 37 oxide oxide NOUN dti-1406 293 38 synthase synthase NOUN dti-1406 293 39 inhibitor inhibitor NOUN dti-1406 293 40 . . PUNCT dti-1406 294 1 neurosci neurosci PROPN dti-1406 294 2 lett lett PROPN dti-1406 294 3 . . PROPN dti-1406 295 1 1994;176:110–114 1994;176:110–114 NUM dti-1406 295 2 . . PUNCT dti-1406 296 1 25 25 NUM dti-1406 296 2 . . PUNCT dti-1406 297 1 murphy murphy PROPN dti-1406 297 2 kp kp PROPN dti-1406 297 3 , , PUNCT dti-1406 297 4 williams williams PROPN dti-1406 297 5 jh jh PROPN dti-1406 297 6 , , PUNCT dti-1406 297 7 bettache bettache PROPN dti-1406 297 8 n n CCONJ dti-1406 297 9 , , PUNCT dti-1406 297 10 bliss bliss ADJ dti-1406 297 11 tv tv NOUN dti-1406 297 12 . . PUNCT dti-1406 298 1 photolytic photolytic ADJ dti-1406 298 2 release release NOUN dti-1406 298 3 of of ADP dti-1406 298 4 nitric nitric ADJ dti-1406 298 5 oxide oxide NOUN dti-1406 298 6 modulates modulate NOUN dti-1406 298 7 nmda nmda ADJ dti-1406 298 8 receptor receptor NOUN dti-1406 298 9 - - PUNCT dti-1406 298 10 mediated mediate VERB dti-1406 298 11 transmission transmission NOUN dti-1406 298 12 but but CCONJ dti-1406 298 13 does do AUX dti-1406 298 14 not not PART dti-1406 298 15 induce induce VERB dti-1406 298 16 long long ADJ dti-1406 298 17 - - PUNCT dti-1406 298 18 term term NOUN dti-1406 298 19 potentiation potentiation NOUN dti-1406 298 20 at at ADP dti-1406 298 21 hippocampal hippocampal ADJ dti-1406 298 22 synapses synapsis NOUN dti-1406 298 23 . . PUNCT dti-1406 299 1 neuropharmacology neuropharmacology NOUN dti-1406 299 2 . . PUNCT dti-1406 300 1 1994;33 1994;33 NUM dti-1406 300 2 : : PUNCT dti-1406 301 1 1375–1385 1375–1385 NUM dti-1406 301 2 . . PUNCT dti-1406 302 1 26 26 NUM dti-1406 302 2 . . PUNCT dti-1406 303 1 hölscher hölscher PROPN dti-1406 303 2 c c PROPN dti-1406 303 3 , , PUNCT dti-1406 303 4 mcglinchey mcglinchey PROPN dti-1406 303 5 l l PROPN dti-1406 303 6 , , PUNCT dti-1406 303 7 anwyl anwyl PROPN dti-1406 303 8 r r PROPN dti-1406 303 9 , , PUNCT dti-1406 303 10 rowan rowan PROPN dti-1406 303 11 mj mj PROPN dti-1406 303 12 . . PROPN dti-1406 303 13 7 7 NUM dti-1406 303 14 - - PUNCT dti-1406 303 15 nitroindazole nitroindazole NOUN dti-1406 303 16 , , PUNCT dti-1406 303 17 a a DET dti-1406 303 18 selective selective ADJ dti-1406 303 19 neuronal neuronal ADJ dti-1406 303 20 nitric nitric ADJ dti-1406 303 21 oxide oxide NOUN dti-1406 303 22 synthase synthase NOUN dti-1406 303 23 inhibitor inhibitor NOUN dti-1406 303 24 in in ADP dti-1406 303 25 vivo vivo NOUN dti-1406 303 26 , , PUNCT dti-1406 303 27 impairs impair VERB dti-1406 303 28 spatial spatial ADJ dti-1406 303 29 learning learning NOUN dti-1406 303 30 in in ADP dti-1406 303 31 the the DET dti-1406 303 32 rat rat NOUN dti-1406 303 33 . . PUNCT dti-1406 303 34 learn learn VERB dti-1406 303 35 mem mem ADJ dti-1406 303 36 . . PUNCT dti-1406 304 1 1996;2:267–278 1996;2:267–278 NUM dti-1406 304 2 . . PUNCT dti-1406 305 1 27 27 NUM dti-1406 305 2 . . PUNCT dti-1406 306 1 mizuno mizuno PROPN dti-1406 306 2 m m PROPN dti-1406 306 3 , , PUNCT dti-1406 306 4 yamada yamada PROPN dti-1406 306 5 k k PROPN dti-1406 306 6 , , PUNCT dti-1406 306 7 olariu olariu VERB dti-1406 306 8 a a PRON dti-1406 306 9 , , PUNCT dti-1406 306 10 nawa nawa PROPN dti-1406 306 11 h h PROPN dti-1406 306 12 , , PUNCT dti-1406 306 13 nabeshima nabeshima PROPN dti-1406 306 14 t. t. PROPN dti-1406 306 15 involvement involvement NOUN dti-1406 306 16 of of ADP dti-1406 306 17 brainderived brainderive VERB dti-1406 306 18 neurotrophic neurotrophic ADJ dti-1406 306 19 factor factor NOUN dti-1406 306 20 in in ADP dti-1406 306 21 spatial spatial ADJ dti-1406 306 22 memory memory NOUN dti-1406 306 23 formation formation NOUN dti-1406 306 24 and and CCONJ dti-1406 306 25 maintenance maintenance NOUN dti-1406 306 26 in in ADP dti-1406 306 27 a a DET dti-1406 306 28 radial radial ADJ dti-1406 306 29 arm arm NOUN dti-1406 306 30 maze maze NOUN dti-1406 306 31 test test NOUN dti-1406 306 32 in in ADP dti-1406 306 33 rats rat NOUN dti-1406 306 34 . . PUNCT dti-1406 307 1 j j PROPN dti-1406 307 2 neurosci neurosci PROPN dti-1406 307 3 . . PUNCT dti-1406 308 1 2000;20:7116–7121 2000;20:7116–7121 NUM dti-1406 308 2 . . PUNCT dti-1406 309 1 28 28 NUM dti-1406 309 2 . . PUNCT dti-1406 310 1 yildiz yildiz NOUN dti-1406 310 2 - - PUNCT dti-1406 310 3 akar akar PROPN dti-1406 310 4 f f NOUN dti-1406 310 5 , , PUNCT dti-1406 310 6 ulak ulak ADV dti-1406 310 7 g g NOUN dti-1406 310 8 , , PUNCT dti-1406 310 9 tanyeri tanyeri PROPN dti-1406 310 10 p p X dti-1406 310 11 , , PUNCT dti-1406 310 12 erden erden X dti-1406 310 13 f f PROPN dti-1406 310 14 , , PUNCT dti-1406 310 15 utkan utkan PROPN dti-1406 310 16 t t PROPN dti-1406 310 17 , , PUNCT dti-1406 310 18 gacar gacar NOUN dti-1406 310 19 n. n. NOUN dti-1406 310 20 7 7 NUM dti-1406 310 21 - - PUNCT dti-1406 310 22 nitroindazole nitroindazole NOUN dti-1406 310 23 , , PUNCT dti-1406 310 24 a a DET dti-1406 310 25 neuronal neuronal ADJ dti-1406 310 26 nitric nitric ADJ dti-1406 310 27 oxide oxide NOUN dti-1406 310 28 synthase synthase NOUN dti-1406 310 29 inhibitor inhibitor NOUN dti-1406 310 30 , , PUNCT dti-1406 310 31 impairs impair VERB dti-1406 310 32 passive passive ADJ dti-1406 310 33 - - PUNCT dti-1406 310 34 avoidance avoidance NOUN dti-1406 310 35 and and CCONJ dti-1406 310 36 elevated elevated ADJ dti-1406 310 37 plus plus CCONJ dti-1406 310 38 - - PUNCT dti-1406 310 39 maze maze NOUN dti-1406 310 40 memory memory NOUN dti-1406 310 41 performance performance NOUN dti-1406 310 42 in in ADP dti-1406 310 43 rats rat NOUN dti-1406 310 44 . . PUNCT dti-1406 311 1 pharmacol pharmacol PROPN dti-1406 311 2 biochem biochem PROPN dti-1406 311 3 behav behav NOUN dti-1406 311 4 . . PUNCT dti-1406 312 1 2007;87:434–443 2007;87:434–443 NUM dti-1406 312 2 . . PUNCT dti-1406 313 1 29 29 NUM dti-1406 313 2 . . PUNCT dti-1406 314 1 reddy reddy PROPN dti-1406 314 2 ds ds PROPN dti-1406 314 3 , , PUNCT dti-1406 314 4 kulkarni kulkarni PROPN dti-1406 314 5 sk sk PROPN dti-1406 314 6 . . PROPN dti-1406 314 7 possible possible ADJ dti-1406 314 8 role role NOUN dti-1406 314 9 of of ADP dti-1406 314 10 nitric nitric ADJ dti-1406 314 11 oxide oxide NOUN dti-1406 314 12 in in ADP dti-1406 314 13 the the DET dti-1406 314 14 nootropic nootropic NOUN dti-1406 314 15 and and CCONJ dti-1406 314 16 antiamnesic antiamnesic ADJ dti-1406 314 17 effects effect NOUN dti-1406 314 18 of of ADP dti-1406 314 19 neurosteroids neurosteroid NOUN dti-1406 314 20 on on ADP dti-1406 314 21 agingand agingand NOUN dti-1406 314 22 dizocilpine dizocilpine NOUN dti-1406 314 23 - - PUNCT dti-1406 314 24 induced induce VERB dti-1406 314 25 learning learning NOUN dti-1406 314 26 impairment impairment NOUN dti-1406 314 27 . . PUNCT dti-1406 315 1 brain brain NOUN dti-1406 315 2 res re NOUN dti-1406 315 3 . . PUNCT dti-1406 316 1 1998;799:215–229 1998;799:215–229 NUM dti-1406 316 2 . . PUNCT dti-1406 317 1 30 30 NUM dti-1406 317 2 . . PUNCT dti-1406 318 1 hlinak hlinak PROPN dti-1406 318 2 z z PROPN dti-1406 318 3 , , PUNCT dti-1406 318 4 krejci krejci PROPN dti-1406 318 5 i. i. PROPN dti-1406 318 6 concurrent concurrent PROPN dti-1406 318 7 administration administration PROPN dti-1406 318 8 of of ADP dti-1406 318 9 subeffective subeffective ADJ dti-1406 318 10 doses dose NOUN dti-1406 318 11 of of ADP dti-1406 318 12 scopolamine scopolamine NOUN dti-1406 318 13 and and CCONJ dti-1406 318 14 mk-801 mk-801 PROPN dti-1406 318 15 produces produce VERB dti-1406 318 16 a a DET dti-1406 318 17 short short ADJ dti-1406 318 18 - - PUNCT dti-1406 318 19 term term NOUN dti-1406 318 20 amnesia amnesia NOUN dti-1406 318 21 for for ADP dti-1406 318 22 the the DET dti-1406 318 23 elevated elevated ADJ dti-1406 318 24 plus plus NOUN dti-1406 318 25 - - PUNCT dti-1406 318 26 maze maze NOUN dti-1406 318 27 in in ADP dti-1406 318 28 mice mouse NOUN dti-1406 318 29 . . PUNCT dti-1406 319 1 behav behav NOUN dti-1406 319 2 brain brain NOUN dti-1406 319 3 res re NOUN dti-1406 319 4 . . PUNCT dti-1406 319 5 1998;91:83–89 1998;91:83–89 NUM dti-1406 319 6 . . PUNCT dti-1406 320 1 31 31 NUM dti-1406 320 2 . . PUNCT dti-1406 321 1 hlinak hlinak PROPN dti-1406 321 2 z z PROPN dti-1406 321 3 , , PUNCT dti-1406 321 4 krejci krejci PROPN dti-1406 321 5 i. i. PROPN dti-1406 321 6 mk-801 mk-801 PROPN dti-1406 321 7 induced induce VERB dti-1406 321 8 amnesia amnesia NOUN dti-1406 321 9 for for ADP dti-1406 321 10 the the DET dti-1406 321 11 elevated elevated ADJ dti-1406 321 12 plus plus NOUN dti-1406 321 13 - - PUNCT dti-1406 321 14 maze maze NOUN dti-1406 321 15 in in ADP dti-1406 321 16 mice mouse NOUN dti-1406 321 17 . . PUNCT dti-1406 322 1 behav behav NOUN dti-1406 322 2 brain brain NOUN dti-1406 322 3 res re NOUN dti-1406 322 4 . . PUNCT dti-1406 322 5 2002;131:221–225 2002;131:221–225 NUM dti-1406 322 6 . . PUNCT dti-1406 323 1 32 32 NUM dti-1406 323 2 . . PUNCT dti-1406 324 1 hlinak hlinak PROPN dti-1406 324 2 z z PROPN dti-1406 324 3 , , PUNCT dti-1406 324 4 krejci krejci PROPN dti-1406 324 5 i. i. PROPN dti-1406 324 6 oxiracetam oxiracetam PROPN dti-1406 324 7 prevents prevent VERB dti-1406 324 8 the the DET dti-1406 324 9 mk-801 mk-801 PROPN dti-1406 324 10 induced induce VERB dti-1406 324 11 amnesia amnesia NOUN dti-1406 324 12 for for ADP dti-1406 324 13 the the DET dti-1406 324 14 elevated elevated ADJ dti-1406 324 15 plus plus NOUN dti-1406 324 16 - - PUNCT dti-1406 324 17 maze maze NOUN dti-1406 324 18 in in ADP dti-1406 324 19 mice mouse NOUN dti-1406 324 20 . . PUNCT dti-1406 325 1 behav behav NOUN dti-1406 325 2 brain brain NOUN dti-1406 325 3 res re NOUN dti-1406 325 4 . . PUNCT dti-1406 325 5 2000;117:147–151 2000;117:147–151 NUM dti-1406 325 6 . . PUNCT dti-1406 326 1 33 33 NUM dti-1406 326 2 . . PUNCT dti-1406 327 1 beuzen beuzen PROPN dti-1406 327 2 a a PROPN dti-1406 327 3 , , PUNCT dti-1406 327 4 belzung belzung PROPN dti-1406 327 5 c c NOUN dti-1406 327 6 , , PUNCT dti-1406 327 7 roullet roullet PROPN dti-1406 327 8 p. p. NOUN dti-1406 327 9 drug drug NOUN dti-1406 327 10 effects effect NOUN dti-1406 327 11 in in ADP dti-1406 327 12 a a DET dti-1406 327 13 radial radial ADJ dti-1406 327 14 maze maze NOUN dti-1406 327 15 designed design VERB dti-1406 327 16 for for ADP dti-1406 327 17 dissociation dissociation NOUN dti-1406 327 18 of of ADP dti-1406 327 19 cues cue NOUN dti-1406 327 20 used use VERB dti-1406 327 21 by by ADP dti-1406 327 22 mice mouse NOUN dti-1406 327 23 . . PUNCT dti-1406 328 1 pharmacol pharmacol PROPN dti-1406 328 2 biochem biochem PROPN dti-1406 328 3 behav behav NOUN dti-1406 328 4 . . PUNCT dti-1406 329 1 1994;48:23–29 1994;48:23–29 NUM dti-1406 329 2 . . PUNCT dti-1406 330 1 34 34 NUM dti-1406 330 2 . . PUNCT dti-1406 331 1 belzung belzung PROPN dti-1406 331 2 c c PROPN dti-1406 331 3 , , PUNCT dti-1406 331 4 le le X dti-1406 331 5 guisquet guisquet PROPN dti-1406 331 6 am am PROPN dti-1406 331 7 , , PUNCT dti-1406 331 8 griebel griebel PROPN dti-1406 331 9 g. g. PROPN dti-1406 331 10 beta beta PROPN dti-1406 331 11 - - PUNCT dti-1406 331 12 cct cct PROPN dti-1406 331 13 , , PUNCT dti-1406 331 14 a a DET dti-1406 331 15 selective selective ADJ dti-1406 331 16 bz bz PROPN dti-1406 331 17 - - PUNCT dti-1406 331 18 v v NOUN dti-1406 331 19 receptor receptor NOUN dti-1406 331 20 antagonist antagonist NOUN dti-1406 331 21 , , PUNCT dti-1406 331 22 blocks block VERB dti-1406 331 23 the the DET dti-1406 331 24 anti anti NOUN dti-1406 331 25 - - NOUN dti-1406 331 26 anxiety anxiety NOUN dti-1406 331 27 but but CCONJ dti-1406 331 28 not not PART dti-1406 331 29 the the DET dti-1406 331 30 amnesic amnesic ADJ dti-1406 331 31 action action NOUN dti-1406 331 32 of of ADP dti-1406 331 33 chlordiazepoxide chlordiazepoxide NOUN dti-1406 331 34 in in ADP dti-1406 331 35 mice mouse NOUN dti-1406 331 36 . . PUNCT dti-1406 332 1 behav behav PROPN dti-1406 332 2 pharmacol pharmacol PROPN dti-1406 332 3 . . PUNCT dti-1406 333 1 2000;11:125–131 2000;11:125–131 X dti-1406 333 2 . . X dti-1406 334 1 35 35 NUM dti-1406 334 2 . . PUNCT dti-1406 335 1 ergün ergün VERB dti-1406 335 2 y y PROPN dti-1406 335 3 , , PUNCT dti-1406 335 4 ergün ergün VERB dti-1406 335 5 ug ug ADP dti-1406 335 6 . . PUNCT dti-1406 336 1 prevention prevention NOUN dti-1406 336 2 of of ADP dti-1406 336 3 pro pro ADJ dti-1406 336 4 - - ADJ dti-1406 336 5 depressant depressant ADJ dti-1406 336 6 effect effect NOUN dti-1406 336 7 of of ADP dti-1406 336 8 l l NOUN dti-1406 336 9 - - NOUN dti-1406 336 10 arginine arginine NOUN dti-1406 336 11 in in ADP dti-1406 336 12 the the DET dti-1406 336 13 forced force VERB dti-1406 336 14 swim swim NOUN dti-1406 336 15 test test NOUN dti-1406 336 16 by by ADP dti-1406 336 17 ng ng PROPN dti-1406 336 18 - - PUNCT dti-1406 336 19 nitro nitro NOUN dti-1406 336 20 - - PUNCT dti-1406 336 21 l l NOUN dti-1406 336 22 - - NOUN dti-1406 336 23 arginine arginine NOUN dti-1406 336 24 and and CCONJ dti-1406 337 1 [ [ X dti-1406 337 2 1h-[1,2,4]oxadiazole[4,3 1h-[1,2,4]oxadiazole[4,3 NUM dti-1406 337 3 - - PUNCT dti-1406 337 4 a a NOUN dti-1406 337 5 ] ] PUNCT dti-1406 337 6 quinoxalin-1 quinoxalin-1 PROPN dti-1406 337 7 - - NOUN dti-1406 337 8 one one NUM dti-1406 337 9 ] ] PUNCT dti-1406 337 10 . . PUNCT dti-1406 338 1 eur eur PROPN dti-1406 338 2 j j PROPN dti-1406 338 3 pharmacol pharmacol PROPN dti-1406 338 4 . . PUNCT dti-1406 338 5 2007;554:150–154 2007;554:150–154 NUM dti-1406 338 6 . . PUNCT dti-1406 339 1 36 36 NUM dti-1406 339 2 . . PUNCT dti-1406 340 1 yıldız yıldız PROPN dti-1406 340 2 akar akar PROPN dti-1406 340 3 f f PROPN dti-1406 340 4 , , PUNCT dti-1406 340 5 komsuoğlu komsuoğlu PROPN dti-1406 340 6 fi fi NOUN dti-1406 340 7 , , PUNCT dti-1406 340 8 ulak ulak ADV dti-1406 340 9 g g NOUN dti-1406 340 10 , , PUNCT dti-1406 340 11 mutlu mutlu PROPN dti-1406 340 12 o. o. NOUN dti-1406 340 13 effects effect NOUN dti-1406 340 14 of of ADP dti-1406 340 15 l l NOUN dti-1406 340 16 - - NOUN dti-1406 340 17 arginine arginine NOUN dti-1406 340 18 on on ADP dti-1406 340 19 7 7 NUM dti-1406 340 20 - - PUNCT dti-1406 340 21 nitroindazole nitroindazole NOUN dti-1406 340 22 - - PUNCT dti-1406 340 23 induced induce VERB dti-1406 340 24 reference reference NOUN dti-1406 340 25 and and CCONJ dti-1406 340 26 working working NOUN dti-1406 340 27 memory memory NOUN dti-1406 340 28 performance performance NOUN dti-1406 340 29 of of ADP dti-1406 340 30 rats rat NOUN dti-1406 340 31 . . PUNCT dti-1406 341 1 pharmacology pharmacology NOUN dti-1406 341 2 . . PUNCT dti-1406 342 1 2009;84:211–218 2009;84:211–218 ADJ dti-1406 342 2 . . PUNCT dti-1406 343 1 37 37 NUM dti-1406 343 2 . . PUNCT dti-1406 344 1 mutlu mutlu PROPN dti-1406 344 2 o o NOUN dti-1406 344 3 , , PUNCT dti-1406 344 4 ulak ulak ADV dti-1406 344 5 g g NOUN dti-1406 344 6 , , PUNCT dti-1406 344 7 belzung belzung PROPN dti-1406 344 8 c. c. PROPN dti-1406 344 9 effects effect NOUN dti-1406 344 10 of of ADP dti-1406 344 11 nitric nitric ADJ dti-1406 344 12 oxide oxide NOUN dti-1406 344 13 synthase synthase NOUN dti-1406 344 14 inhibitors inhibitor NOUN dti-1406 344 15 1-(2 1-(2 PROPN dti-1406 344 16 trifluoromethylphenyl)—imidazole trifluoromethylphenyl)—imidazole NOUN dti-1406 344 17 ( ( PUNCT dti-1406 344 18 trim trim ADJ dti-1406 344 19 ) ) PUNCT dti-1406 344 20 and and CCONJ dti-1406 344 21 7 7 NUM dti-1406 344 22 - - PUNCT dti-1406 344 23 nitroindazole nitroindazole NOUN dti-1406 344 24 ( ( PUNCT dti-1406 344 25 7 7 NUM dti-1406 344 26 - - PUNCT dti-1406 344 27 ni ni NOUN dti-1406 344 28 ) ) PUNCT dti-1406 344 29 on on ADP dti-1406 344 30 learning learning NOUN dti-1406 344 31 and and CCONJ dti-1406 344 32 memory memory NOUN dti-1406 344 33 in in ADP dti-1406 344 34 mice mouse NOUN dti-1406 344 35 . . PUNCT dti-1406 345 1 fundam fundam PROPN dti-1406 345 2 clin clin PROPN dti-1406 345 3 pharmacol pharmacol PROPN dti-1406 345 4 . . PUNCT dti-1406 345 5 2011;25:368–377 2011;25:368–377 NOUN dti-1406 345 6 . . PUNCT dti-1406 346 1 38 38 NUM dti-1406 346 2 . . PUNCT dti-1406 347 1 cain cain PROPN dti-1406 347 2 dp dp PROPN dti-1406 347 3 . . PUNCT dti-1406 348 1 testing test VERB dti-1406 348 2 the the DET dti-1406 348 3 nmda nmda ADJ dti-1406 348 4 , , PUNCT dti-1406 348 5 long long ADJ dti-1406 348 6 - - PUNCT dti-1406 348 7 term term NOUN dti-1406 348 8 potentiation potentiation NOUN dti-1406 348 9 , , PUNCT dti-1406 348 10 and and CCONJ dti-1406 348 11 cholinergic cholinergic ADJ dti-1406 348 12 hypotheses hypothesis NOUN dti-1406 348 13 of of ADP dti-1406 348 14 spatial spatial ADJ dti-1406 348 15 learning learning NOUN dti-1406 348 16 . . PUNCT dti-1406 349 1 neurosci neurosci PROPN dti-1406 349 2 biobehav biobehav PROPN dti-1406 349 3 rev rev PROPN dti-1406 349 4 . . PROPN dti-1406 350 1 1998;22:181–193 1998;22:181–193 NUM dti-1406 350 2 . . NOUN dti-1406 351 1 39 39 NUM dti-1406 351 2 . . PUNCT dti-1406 352 1 nagai nagai PROPN dti-1406 352 2 t t PROPN dti-1406 352 3 , , PUNCT dti-1406 352 4 kamei kamei PROPN dti-1406 352 5 h h PROPN dti-1406 352 6 , , PUNCT dti-1406 352 7 dohniwa dohniwa VERB dti-1406 352 8 m m PROPN dti-1406 352 9 , , PUNCT dti-1406 352 10 et et PROPN dti-1406 352 11 al al PROPN dti-1406 352 12 . . PUNCT dti-1406 353 1 involvement involvement NOUN dti-1406 353 2 of of ADP dti-1406 353 3 hippocampal hippocampal ADJ dti-1406 353 4 extracellular extracellular ADJ dti-1406 353 5 signal signal NOUN dti-1406 353 6 - - PUNCT dti-1406 353 7 regulated regulate VERB dti-1406 353 8 kinase kinase NOUN dti-1406 353 9 1/2 1/2 NUM dti-1406 353 10 in in ADP dti-1406 353 11 spatial spatial ADJ dti-1406 353 12 working working NOUN dti-1406 353 13 memory memory NOUN dti-1406 353 14 in in ADP dti-1406 353 15 rats rat NOUN dti-1406 353 16 . . PUNCT dti-1406 354 1 neuroreport neuroreport NOUN dti-1406 354 2 . . PUNCT dti-1406 355 1 2006 2006 NUM dti-1406 355 2 ; ; PUNCT dti-1406 355 3 17:1453–1457 17:1453–1457 NUM dti-1406 355 4 . . NOUN dti-1406 355 5 40 40 NUM dti-1406 355 6 . . PUNCT dti-1406 356 1 sharma sharma PROPN dti-1406 356 2 ac ac PROPN dti-1406 356 3 , , PUNCT dti-1406 356 4 kulkarni kulkarni PROPN dti-1406 356 5 sk sk PROPN dti-1406 356 6 . . PROPN dti-1406 356 7 evaluation evaluation NOUN dti-1406 356 8 of of ADP dti-1406 356 9 learning learning NOUN dti-1406 356 10 and and CCONJ dti-1406 356 11 memory memory NOUN dti-1406 356 12 mechanisms mechanism NOUN dti-1406 356 13 employing employ VERB dti-1406 356 14 elevated elevated ADJ dti-1406 356 15 plus plus CCONJ dti-1406 356 16 - - PUNCT dti-1406 356 17 maze maze NOUN dti-1406 356 18 in in ADP dti-1406 356 19 rats rat NOUN dti-1406 356 20 and and CCONJ dti-1406 356 21 mice mouse NOUN dti-1406 356 22 . . PUNCT dti-1406 357 1 prog prog PROPN dti-1406 357 2 neuropsychopharmacol neuropsychopharmacol PROPN dti-1406 357 3 biol biol PROPN dti-1406 357 4 psychiatry psychiatry NOUN dti-1406 357 5 . . PUNCT dti-1406 358 1 1992;16:117–125 1992;16:117–125 NUM dti-1406 358 2 . . PUNCT dti-1406 359 1 http://www.la-press.com http://www.la-press.com X dti-1406 359 2 http://www.la-press.com/drug-target-insights-journal-j23 http://www.la-press.com/drug-target-insights-journal-j23 AUX dti-1406 359 3 mutlu mutlu PROPN dti-1406 359 4 et et PROPN dti-1406 359 5 al al PROPN dti-1406 359 6 8 8 NUM dti-1406 359 7 drug drug NOUN dti-1406 359 8 target target NOUN dti-1406 359 9 insights insight NOUN dti-1406 359 10 2015:9 2015:9 PRON dti-1406 359 11 41 41 NUM dti-1406 359 12 . . PUNCT dti-1406 360 1 hunter hunter PROPN dti-1406 360 2 b b PROPN dti-1406 360 3 , , PUNCT dti-1406 360 4 zornetzer zornetzer NOUN dti-1406 360 5 sf sf PROPN dti-1406 360 6 , , PUNCT dti-1406 360 7 jarvik jarvik PROPN dti-1406 360 8 me i PRON dti-1406 360 9 , , PUNCT dti-1406 360 10 mcgaugh mcgaugh PROPN dti-1406 360 11 jl jl PROPN dti-1406 360 12 . . PUNCT dti-1406 360 13 modulation modulation NOUN dti-1406 360 14 of of ADP dti-1406 360 15 learning learning NOUN dti-1406 360 16 and and CCONJ dti-1406 360 17 memory memory NOUN dti-1406 360 18 : : PUNCT dti-1406 360 19 effects effect NOUN dti-1406 360 20 of of ADP dti-1406 360 21 drugs drug NOUN dti-1406 360 22 influencing influence VERB dti-1406 360 23 neurotransmitters neurotransmitter NOUN dti-1406 360 24 . . PUNCT dti-1406 361 1 in in ADP dti-1406 361 2 : : PUNCT dti-1406 361 3 iversen iversen NOUN dti-1406 361 4 ll ll AUX dti-1406 361 5 , , PUNCT dti-1406 361 6 iversen iversen VERB dti-1406 361 7 sd sd PROPN dti-1406 361 8 , , PUNCT dti-1406 361 9 snyder snyder PROPN dti-1406 361 10 sh sh PROPN dti-1406 361 11 , , PUNCT dti-1406 361 12 eds eds PROPN dti-1406 361 13 . . PUNCT dti-1406 361 14 handbook handbook NOUN dti-1406 361 15 of of ADP dti-1406 361 16 psychopharmacology psychopharmacology NOUN dti-1406 361 17 . . PUNCT dti-1406 362 1 vol vol NOUN dti-1406 362 2 19 19 NUM dti-1406 362 3 . . PUNCT dti-1406 363 1 new new PROPN dti-1406 363 2 york york PROPN dti-1406 363 3 : : PUNCT dti-1406 363 4 plenum plenum PROPN dti-1406 363 5 press press PROPN dti-1406 363 6 ; ; PUNCT dti-1406 364 1 1988:531–577 1988:531–577 X dti-1406 364 2 . . PUNCT dti-1406 364 3 42 42 NUM dti-1406 364 4 . . PUNCT dti-1406 365 1 komsuoglu komsuoglu NOUN dti-1406 365 2 - - PUNCT dti-1406 365 3 celikyurt celikyurt NOUN dti-1406 365 4 i i PRON dti-1406 365 5 , , PUNCT dti-1406 365 6 gocmez gocmez PROPN dti-1406 365 7 ss ss PROPN dti-1406 365 8 , , PUNCT dti-1406 365 9 mutlu mutlu PROPN dti-1406 365 10 o o NOUN dti-1406 365 11 , , PUNCT dti-1406 365 12 gacar gacar NOUN dti-1406 365 13 n n CCONJ dti-1406 365 14 , , PUNCT dti-1406 365 15 aricioglu aricioglu PROPN dti-1406 365 16 f f PROPN dti-1406 365 17 , , PUNCT dti-1406 365 18 utkan utkan ADJ dti-1406 365 19 t. t. NOUN dti-1406 365 20 evidence evidence NOUN dti-1406 365 21 for for ADP dti-1406 365 22 the the DET dti-1406 365 23 involvement involvement NOUN dti-1406 365 24 of of ADP dti-1406 365 25 neuronal neuronal ADJ dti-1406 365 26 nitric nitric ADJ dti-1406 365 27 oxide oxide NOUN dti-1406 365 28 synthase synthase NOUN dti-1406 365 29 and and CCONJ dti-1406 365 30 soluble soluble ADJ dti-1406 365 31 guanylate guanylate NOUN dti-1406 365 32 cyclase cyclase NOUN dti-1406 365 33 on on ADP dti-1406 365 34 cognitive cognitive ADJ dti-1406 365 35 functions function NOUN dti-1406 365 36 in in ADP dti-1406 365 37 rats rat NOUN dti-1406 365 38 . . PUNCT dti-1406 366 1 life life NOUN dti-1406 366 2 sci sci PROPN dti-1406 366 3 . . PUNCT dti-1406 367 1 2011;89(23–24):905–910 2011;89(23–24):905–910 X dti-1406 367 2 . . PROPN dti-1406 367 3 43 43 NUM dti-1406 367 4 . . PUNCT dti-1406 368 1 rickard rickard PROPN dti-1406 368 2 ns ns PROPN dti-1406 368 3 , , PUNCT dti-1406 368 4 gibbs gibbs PROPN dti-1406 368 5 me i PRON dti-1406 368 6 , , PUNCT dti-1406 368 7 ng ng PROPN dti-1406 368 8 kt kt PROPN dti-1406 368 9 . . PUNCT dti-1406 369 1 inhibition inhibition NOUN dti-1406 369 2 of of ADP dti-1406 369 3 the the DET dti-1406 369 4 endothelial endothelial ADJ dti-1406 369 5 isoform isoform NOUN dti-1406 369 6 of of ADP dti-1406 369 7 nitric nitric ADJ dti-1406 369 8 oxide oxide NOUN dti-1406 369 9 synthase synthase NOUN dti-1406 369 10 impairs impair VERB dti-1406 369 11 long long ADJ dti-1406 369 12 - - PUNCT dti-1406 369 13 term term NOUN dti-1406 369 14 memory memory NOUN dti-1406 369 15 formation formation NOUN dti-1406 369 16 in in ADP dti-1406 369 17 the the DET dti-1406 369 18 chick chick NOUN dti-1406 369 19 . . PUNCT dti-1406 370 1 learn learn VERB dti-1406 370 2 mem mem PROPN dti-1406 370 3 . . PUNCT dti-1406 370 4 1999;6(5):6458–6466 1999;6(5):6458–6466 NUM dti-1406 370 5 . . PUNCT dti-1406 371 1 44 44 NUM dti-1406 371 2 . . PUNCT dti-1406 372 1 son son PROPN dti-1406 372 2 h h PROPN dti-1406 372 3 , , PUNCT dti-1406 372 4 hawkins hawkins PROPN dti-1406 372 5 rd rd PROPN dti-1406 372 6 , , PUNCT dti-1406 372 7 martin martin PROPN dti-1406 372 8 k k PROPN dti-1406 372 9 , , PUNCT dti-1406 372 10 kiebler kiebler PROPN dti-1406 372 11 m m PROPN dti-1406 372 12 , , PUNCT dti-1406 372 13 huang huang PROPN dti-1406 372 14 pl pl PROPN dti-1406 372 15 , , PUNCT dti-1406 372 16 fishman fishman PROPN dti-1406 372 17 mc mc PROPN dti-1406 372 18 . . PROPN dti-1406 373 1 longterm longterm PROPN dti-1406 373 2 potentiation potentiation NOUN dti-1406 373 3 is be AUX dti-1406 373 4 reduced reduce VERB dti-1406 373 5 in in ADP dti-1406 373 6 mice mouse NOUN dti-1406 373 7 that that PRON dti-1406 373 8 are be AUX dti-1406 373 9 doubly doubly ADV dti-1406 373 10 mutant mutant ADJ dti-1406 373 11 in in ADP dti-1406 373 12 endothelial endothelial ADJ dti-1406 373 13 and and CCONJ dti-1406 373 14 neuronal neuronal ADJ dti-1406 373 15 nitric nitric ADJ dti-1406 373 16 oxide oxide NOUN dti-1406 373 17 synthase synthase NOUN dti-1406 373 18 . . PUNCT dti-1406 374 1 cell cell NOUN dti-1406 374 2 . . PUNCT dti-1406 375 1 1996;87:1015–1023 1996;87:1015–1023 NUM dti-1406 375 2 . . PUNCT dti-1406 376 1 45 45 NUM dti-1406 376 2 . . PUNCT dti-1406 376 3 pitsikas pitsikas PROPN dti-1406 376 4 n n CCONJ dti-1406 376 5 , , PUNCT dti-1406 376 6 rigamonti rigamonti PROPN dti-1406 376 7 ae ae PROPN dti-1406 376 8 , , PUNCT dti-1406 376 9 cella cella PROPN dti-1406 376 10 sg sg PROPN dti-1406 376 11 , , PUNCT dti-1406 376 12 locatelli locatelli PROPN dti-1406 376 13 v v NOUN dti-1406 376 14 , , PUNCT dti-1406 376 15 sala sala PROPN dti-1406 376 16 m m PROPN dti-1406 376 17 , , PUNCT dti-1406 376 18 muller muller PROPN dti-1406 376 19 ee ee PROPN dti-1406 376 20 . . PUNCT dti-1406 376 21 effects effect NOUN dti-1406 376 22 of of ADP dti-1406 376 23 molsidomine molsidomine NOUN dti-1406 376 24 on on ADP dti-1406 376 25 scopolamine scopolamine NOUN dti-1406 376 26 - - PUNCT dti-1406 376 27 induced induce VERB dti-1406 376 28 amnesia amnesia NOUN dti-1406 376 29 and and CCONJ dti-1406 376 30 hypermotility hypermotility NOUN dti-1406 376 31 in in ADP dti-1406 376 32 the the DET dti-1406 376 33 rat rat NOUN dti-1406 376 34 . . PROPN dti-1406 376 35 eur eur PROPN dti-1406 376 36 j j PROPN dti-1406 376 37 pharmacol pharmacol PROPN dti-1406 376 38 . . PUNCT dti-1406 377 1 2001;426:193–200 2001;426:193–200 NUM dti-1406 377 2 . . PUNCT dti-1406 378 1 46 46 NUM dti-1406 378 2 . . PUNCT dti-1406 379 1 guevara guevara PROPN dti-1406 379 2 - - PUNCT dti-1406 379 3 guzman guzman PROPN dti-1406 379 4 r r PROPN dti-1406 379 5 , , PUNCT dti-1406 379 6 emson emson PROPN dti-1406 379 7 pc pc PROPN dti-1406 379 8 , , PUNCT dti-1406 379 9 kendrick kendrick PROPN dti-1406 379 10 km km PROPN dti-1406 379 11 . . PUNCT dti-1406 380 1 modulation modulation NOUN dti-1406 380 2 of of ADP dti-1406 380 3 in in ADP dti-1406 380 4 vivo vivo ADJ dti-1406 380 5 striatal striatal ADJ dti-1406 380 6 transmitter transmitter NOUN dti-1406 380 7 release release NOUN dti-1406 380 8 by by ADP dti-1406 380 9 nitric nitric ADJ dti-1406 380 10 oxide oxide NOUN dti-1406 380 11 and and CCONJ dti-1406 380 12 cyclic cyclic PROPN dti-1406 380 13 gmp gmp PROPN dti-1406 380 14 . . PUNCT dti-1406 381 1 j j PROPN dti-1406 381 2 neurochem neurochem PROPN dti-1406 381 3 . . PUNCT dti-1406 382 1 1994;62 1994;62 NUM dti-1406 382 2 : : PUNCT dti-1406 383 1 807–810 807–810 NUM dti-1406 383 2 . . PUNCT dti-1406 384 1 47 47 NUM dti-1406 384 2 . . PUNCT dti-1406 385 1 böhme böhme PROPN dti-1406 385 2 ga ga PROPN dti-1406 385 3 , , PUNCT dti-1406 385 4 bon bon PROPN dti-1406 385 5 c c PROPN dti-1406 385 6 , , PUNCT dti-1406 385 7 lemaire lemaire PROPN dti-1406 385 8 m m PROPN dti-1406 385 9 , , PUNCT dti-1406 385 10 et et PROPN dti-1406 385 11 al al PROPN dti-1406 385 12 . . PROPN dti-1406 385 13 altered alter VERB dti-1406 385 14 synaptic synaptic ADJ dti-1406 385 15 plasticity plasticity NOUN dti-1406 385 16 and and CCONJ dti-1406 385 17 memory memory NOUN dti-1406 385 18 formation formation NOUN dti-1406 385 19 in in ADP dti-1406 385 20 nitric nitric ADJ dti-1406 385 21 oxide oxide NOUN dti-1406 385 22 synthase synthase NOUN dti-1406 385 23 inhibitor inhibitor NOUN dti-1406 385 24 - - PUNCT dti-1406 385 25 treated treat VERB dti-1406 385 26 rats rat NOUN dti-1406 385 27 . . PUNCT dti-1406 386 1 proc proc PROPN dti-1406 386 2 natl natl PROPN dti-1406 386 3 acad acad PROPN dti-1406 386 4 sci sci PROPN dti-1406 386 5 u u PROPN dti-1406 386 6 s s NOUN dti-1406 386 7 a. a. NOUN dti-1406 386 8 1993;90:9191–9194 1993;90:9191–9194 NUM dti-1406 386 9 . . PUNCT dti-1406 387 1 48 48 NUM dti-1406 387 2 . . PUNCT dti-1406 388 1 telegdy telegdy PROPN dti-1406 388 2 g g PROPN dti-1406 388 3 , , PUNCT dti-1406 388 4 kokavszky kokavszky PROPN dti-1406 388 5 r. r. PROPN dti-1406 388 6 the the DET dti-1406 388 7 role role NOUN dti-1406 388 8 of of ADP dti-1406 388 9 nitric nitric ADJ dti-1406 388 10 oxide oxide NOUN dti-1406 388 11 in in ADP dti-1406 388 12 passive passive ADJ dti-1406 388 13 avoidance avoidance NOUN dti-1406 388 14 learning learning NOUN dti-1406 388 15 . . PUNCT dti-1406 389 1 neuropharmacology neuropharmacology NOUN dti-1406 389 2 . . PUNCT dti-1406 390 1 1997;36:1583–1587 1997;36:1583–1587 PROPN dti-1406 390 2 . . PUNCT dti-1406 391 1 49 49 NUM dti-1406 391 2 . . PUNCT dti-1406 392 1 finn finn PROPN dti-1406 392 2 c c PROPN dti-1406 392 3 , , PUNCT dti-1406 392 4 da da PROPN dti-1406 392 5 cunha cunha NOUN dti-1406 392 6 c c PROPN dti-1406 392 7 , , PUNCT dti-1406 392 8 bromberg bromberg PROPN dti-1406 392 9 e e PROPN dti-1406 392 10 , , PUNCT dti-1406 392 11 et et PROPN dti-1406 392 12 al al PROPN dti-1406 392 13 . . PUNCT dti-1406 393 1 experiments experiment NOUN dti-1406 393 2 suggesting suggest VERB dti-1406 393 3 a a DET dti-1406 393 4 role role NOUN dti-1406 393 5 for for ADP dti-1406 393 6 nitric nitric ADJ dti-1406 393 7 oxide oxide NOUN dti-1406 393 8 in in ADP dti-1406 393 9 the the DET dti-1406 393 10 hippocampus hippocampus NOUN dti-1406 393 11 in in ADP dti-1406 393 12 memory memory NOUN dti-1406 393 13 processes process NOUN dti-1406 393 14 . . PUNCT dti-1406 394 1 neurobiol neurobiol PROPN dti-1406 394 2 learn learn VERB dti-1406 394 3 mem mem PROPN dti-1406 394 4 . . PUNCT dti-1406 395 1 1995;63 1995;63 NOUN dti-1406 395 2 : : PUNCT dti-1406 396 1 113–115 113–115 NUM dti-1406 396 2 . . PUNCT dti-1406 397 1 50 50 NUM dti-1406 397 2 . . PUNCT dti-1406 398 1 kopf kopf PROPN dti-1406 398 2 sr sr PROPN dti-1406 398 3 , , PUNCT dti-1406 398 4 benton benton PROPN dti-1406 398 5 sr sr PROPN dti-1406 398 6 , , PUNCT dti-1406 398 7 kanfin kanfin PROPN dti-1406 398 8 r r PROPN dti-1406 398 9 , , PUNCT dti-1406 398 10 giovannini giovannini ADJ dti-1406 398 11 mg mg PROPN dti-1406 398 12 , , PUNCT dti-1406 398 13 pepeu pepeu PROPN dti-1406 398 14 g. g. NOUN dti-1406 398 15 no no DET dti-1406 398 16 synthesis synthesis NOUN dti-1406 398 17 inhibition inhibition NOUN dti-1406 398 18 decreases decrease VERB dti-1406 398 19 cortical cortical ADJ dti-1406 398 20 ach ach NOUN dti-1406 398 21 release release NOUN dti-1406 398 22 and and CCONJ dti-1406 398 23 impairs impair VERB dti-1406 398 24 retention retention NOUN dti-1406 398 25 of of ADP dti-1406 398 26 a a DET dti-1406 398 27 conditioned condition VERB dti-1406 398 28 response response NOUN dti-1406 398 29 . . PUNCT dti-1406 399 1 brain brain NOUN dti-1406 399 2 res re NOUN dti-1406 399 3 . . PUNCT dti-1406 400 1 2001;894:141–144 2001;894:141–144 NUM dti-1406 400 2 . . PUNCT dti-1406 401 1 51 51 NUM dti-1406 401 2 . . PUNCT dti-1406 402 1 toyoda toyoda PROPN dti-1406 402 2 m m PROPN dti-1406 402 3 , , PUNCT dti-1406 402 4 saito saito PROPN dti-1406 402 5 h h PROPN dti-1406 402 6 , , PUNCT dti-1406 402 7 matsuki matsuki PROPN dti-1406 402 8 n. n. PROPN dti-1406 402 9 nitric nitric ADJ dti-1406 402 10 oxide oxide NOUN dti-1406 402 11 but but CCONJ dti-1406 402 12 not not PART dti-1406 402 13 carbonmonoxide carbonmonoxide NOUN dti-1406 402 14 is be AUX dti-1406 402 15 involved involve VERB dti-1406 402 16 in in ADP dti-1406 402 17 spatial spatial ADJ dti-1406 402 18 learning learning NOUN dti-1406 402 19 of of ADP dti-1406 402 20 mice mouse NOUN dti-1406 402 21 . . PUNCT dti-1406 403 1 jpn jpn PROPN dti-1406 403 2 j j PROPN dti-1406 403 3 pharmacol pharmacol PROPN dti-1406 403 4 . . PUNCT dti-1406 404 1 1996;71:205–211 1996;71:205–211 PROPN dti-1406 404 2 . . PUNCT dti-1406 405 1 52 52 NUM dti-1406 405 2 . . PUNCT dti-1406 406 1 prendergast prendergast PROPN dti-1406 406 2 ma ma PROPN dti-1406 406 3 , , PUNCT dti-1406 406 4 buccafusco buccafusco PROPN dti-1406 406 5 jj jj PROPN dti-1406 406 6 , , PUNCT dti-1406 406 7 terry terry PROPN dti-1406 406 8 av av PROPN dti-1406 406 9 jr jr PROPN dti-1406 406 10 . . PROPN dti-1406 406 11 nitric nitric ADJ dti-1406 406 12 oxide oxide NOUN dti-1406 406 13 inhibition inhibition NOUN dti-1406 406 14 impairs impair VERB dti-1406 406 15 spatial spatial ADJ dti-1406 406 16 navigation navigation NOUN dti-1406 406 17 learning learning NOUN dti-1406 406 18 and and CCONJ dti-1406 406 19 induces induce VERB dti-1406 406 20 contitioned contitione VERB dti-1406 406 21 taste taste NOUN dti-1406 406 22 aversion aversion NOUN dti-1406 406 23 . . PUNCT dti-1406 407 1 pharmacol pharmacol PROPN dti-1406 407 2 biochem biochem PROPN dti-1406 407 3 behav behav NOUN dti-1406 407 4 . . PUNCT dti-1406 408 1 1998;57:347–352 1998;57:347–352 NOUN dti-1406 408 2 . . PUNCT dti-1406 409 1 53 53 NUM dti-1406 409 2 . . PUNCT dti-1406 410 1 zou zou PROPN dti-1406 410 2 lb lb PROPN dti-1406 410 3 , , PUNCT dti-1406 410 4 yamada yamada PROPN dti-1406 410 5 k k PROPN dti-1406 410 6 , , PUNCT dti-1406 410 7 tanaka tanaka PROPN dti-1406 410 8 t t PROPN dti-1406 410 9 , , PUNCT dti-1406 410 10 kameyama kameyama PROPN dti-1406 410 11 t t PROPN dti-1406 410 12 , , PUNCT dti-1406 410 13 nabeshima nabeshima PROPN dti-1406 410 14 t. t. ADJ dti-1406 410 15 nitric nitric ADJ dti-1406 410 16 oxide oxide NOUN dti-1406 410 17 synthase synthase NOUN dti-1406 410 18 inhibitors inhibitor NOUN dti-1406 410 19 impair impair VERB dti-1406 410 20 reference reference NOUN dti-1406 410 21 memory memory NOUN dti-1406 410 22 formation formation NOUN dti-1406 410 23 in in ADP dti-1406 410 24 a a DET dti-1406 410 25 radial radial ADJ dti-1406 410 26 arm arm NOUN dti-1406 410 27 maze maze NOUN dti-1406 410 28 . . PUNCT dti-1406 411 1 neuropharmacology neuropharmacology NOUN dti-1406 411 2 . . PUNCT dti-1406 412 1 1998;37:323–330 1998;37:323–330 NUM dti-1406 412 2 . . PUNCT dti-1406 413 1 54 54 NUM dti-1406 413 2 . . PUNCT dti-1406 414 1 edwards edwards PROPN dti-1406 414 2 tm tm PROPN dti-1406 414 3 , , PUNCT dti-1406 414 4 rickard rickard PROPN dti-1406 414 5 ns ns PROPN dti-1406 414 6 , , PUNCT dti-1406 414 7 ng ng PROPN dti-1406 414 8 kt kt PROPN dti-1406 414 9 . . PUNCT dti-1406 414 10 inhibition inhibition NOUN dti-1406 414 11 of of ADP dti-1406 414 12 guanylate guanylate NOUN dti-1406 414 13 cyclase cyclase NOUN dti-1406 414 14 and and CCONJ dti-1406 414 15 protein protein NOUN dti-1406 414 16 kinase kinase PROPN dti-1406 414 17 g g PROPN dti-1406 414 18 impairs impair VERB dti-1406 414 19 retention retention NOUN dti-1406 414 20 for for ADP dti-1406 414 21 the the DET dti-1406 414 22 passive passive ADJ dti-1406 414 23 avoidance avoidance NOUN dti-1406 414 24 in in ADP dti-1406 414 25 the the DET dti-1406 414 26 day day NOUN dti-1406 414 27 old old ADJ dti-1406 414 28 chick chick NOUN dti-1406 414 29 . . PUNCT dti-1406 415 1 neurobiol neurobiol PROPN dti-1406 415 2 learn learn VERB dti-1406 415 3 mem mem ADJ dti-1406 415 4 . . PUNCT dti-1406 416 1 2002;77:313–326 2002;77:313–326 NOUN dti-1406 416 2 . . PUNCT dti-1406 417 1 55 55 NUM dti-1406 417 2 . . PUNCT dti-1406 418 1 kleppisch kleppisch PROPN dti-1406 418 2 t t PROPN dti-1406 418 3 , , PUNCT dti-1406 418 4 pfeifer pfeifer PROPN dti-1406 418 5 a a PRON dti-1406 418 6 , , PUNCT dti-1406 418 7 klatt klatt PROPN dti-1406 418 8 p p X dti-1406 418 9 , , PUNCT dti-1406 418 10 et et PROPN dti-1406 418 11 al al PROPN dti-1406 418 12 . . PUNCT dti-1406 419 1 long long ADJ dti-1406 419 2 - - PUNCT dti-1406 419 3 term term NOUN dti-1406 419 4 potentiation potentiation NOUN dti-1406 419 5 in in ADP dti-1406 419 6 the the DET dti-1406 419 7 hippocampal hippocampal PROPN dti-1406 419 8 ca1 ca1 PROPN dti-1406 419 9 region region PROPN dti-1406 419 10 ofmice ofmice PROPN dti-1406 419 11 lacking lack VERB dti-1406 419 12 cgmp cgmp PROPN dti-1406 419 13 - - ADJ dti-1406 419 14 dependent dependent ADJ dti-1406 419 15 kinases kinase NOUN dti-1406 419 16 is be AUX dti-1406 419 17 normal normal ADJ dti-1406 419 18 and and CCONJ dti-1406 419 19 susceptible susceptible ADJ dti-1406 419 20 to to ADP dti-1406 419 21 inhibition inhibition NOUN dti-1406 419 22 of of ADP dti-1406 419 23 nitric nitric ADJ dti-1406 419 24 oxide oxide NOUN dti-1406 419 25 synthase synthase NOUN dti-1406 419 26 . . PUNCT dti-1406 420 1 j j PROPN dti-1406 420 2 neurosci neurosci PROPN dti-1406 420 3 . . PUNCT dti-1406 421 1 1999;19:48–55 1999;19:48–55 NUM dti-1406 421 2 . . PUNCT dti-1406 422 1 http://www.la-press.com http://www.la-press.com X dti-1406 422 2 http://www.la-press.com/drug-target-insights-journal-j23 http://www.la-press.com/drug-target-insights-journal-j23 PROPN