id	sid	tid	token	lemma	pos
dti-1418	1	1	https://doi.org/10.1177/1177392819861114	https://doi.org/10.1177/1177392819861114	NOUN
dti-1418	1	2	drug	drug	NOUN
dti-1418	1	3	target	target	NOUN
dti-1418	1	4	insights	insight	NOUN
dti-1418	1	5	volume	volume	VERB
dti-1418	1	6	13	13	NUM
dti-1418	1	7	:	:	SYM
dti-1418	1	8	1–7	1–7	NUM
dti-1418	1	9	©	©	ADP
dti-1418	1	10	the	the	DET
dti-1418	1	11	author(s	author(s	PROPN
dti-1418	1	12	)	)	PUNCT
dti-1418	1	13	2019	2019	NUM
dti-1418	1	14	article	article	NOUN
dti-1418	1	15	reuse	reuse	VERB
dti-1418	1	16	guidelines	guideline	NOUN
dti-1418	1	17	:	:	PUNCT
dti-1418	1	18	sagepub.com/journals-permissions	sagepub.com/journals-permission	NOUN
dti-1418	1	19	doi	doi	NOUN
dti-1418	1	20	:	:	PUNCT
dti-1418	1	21	10.1177/1177392819861114	10.1177/1177392819861114	NUM
dti-1418	1	22	creative	creative	ADJ
dti-1418	1	23	commons	common	NOUN
dti-1418	1	24	non	non	ADJ
dti-1418	1	25	commercial	commercial	PROPN
dti-1418	1	26	cc	cc	PROPN
dti-1418	1	27	by	by	ADP
dti-1418	1	28	-	-	PUNCT
dti-1418	1	29	nc	nc	PROPN
dti-1418	1	30	:	:	PUNCT
dti-1418	1	31	this	this	DET
dti-1418	1	32	article	article	NOUN
dti-1418	1	33	is	be	AUX
dti-1418	1	34	distributed	distribute	VERB
dti-1418	1	35	under	under	ADP
dti-1418	1	36	the	the	DET
dti-1418	1	37	terms	term	NOUN
dti-1418	1	38	of	of	ADP
dti-1418	1	39	the	the	DET
dti-1418	1	40	creative	creative	ADJ
dti-1418	1	41	commons	common	NOUN
dti-1418	1	42	attribution	attribution	NOUN
dti-1418	1	43	-	-	PUNCT
dti-1418	1	44	noncommercial	noncommercial	ADJ
dti-1418	1	45	4.0	4.0	NUM
dti-1418	1	46	license	license	NOUN
dti-1418	1	47	(	(	PUNCT
dti-1418	1	48	http://www.creativecommons.org/licenses/by-nc/4.0/	http://www.creativecommons.org/licenses/by-nc/4.0/	PROPN
dti-1418	1	49	)	)	PUNCT
dti-1418	1	50	which	which	PRON
dti-1418	1	51	permits	permit	VERB
dti-1418	1	52	non	non	ADJ
dti-1418	1	53	-	-	ADJ
dti-1418	1	54	commercial	commercial	ADJ
dti-1418	1	55	use	use	NOUN
dti-1418	1	56	,	,	PUNCT
dti-1418	1	57	reproduction	reproduction	NOUN
dti-1418	1	58	and	and	CCONJ
dti-1418	1	59	distribution	distribution	NOUN
dti-1418	1	60	of	of	ADP
dti-1418	1	61	the	the	DET
dti-1418	1	62	work	work	NOUN
dti-1418	1	63	without	without	ADP
dti-1418	1	64	further	further	ADJ
dti-1418	1	65	permission	permission	NOUN
dti-1418	1	66	provided	provide	VERB
dti-1418	1	67	the	the	DET
dti-1418	1	68	original	original	ADJ
dti-1418	1	69	work	work	NOUN
dti-1418	1	70	is	be	AUX
dti-1418	1	71	attributed	attribute	VERB
dti-1418	1	72	as	as	ADP
dti-1418	1	73	specified	specify	VERB
dti-1418	1	74	on	on	ADP
dti-1418	1	75	the	the	DET
dti-1418	1	76	sage	sage	NOUN
dti-1418	1	77	and	and	CCONJ
dti-1418	1	78	open	open	ADJ
dti-1418	1	79	access	access	NOUN
dti-1418	1	80	pages	page	NOUN
dti-1418	1	81	(	(	PUNCT
dti-1418	1	82	https://us.sagepub.com/en-us/nam/open-access-at-sage	https://us.sagepub.com/en-us/nam/open-access-at-sage	NOUN
dti-1418	1	83	)	)	PUNCT
dti-1418	1	84	.	.	PUNCT
dti-1418	2	1	introduction	introduction	NOUN
dti-1418	2	2	atrial	atrial	ADJ
dti-1418	2	3	fibrillation	fibrillation	NOUN
dti-1418	2	4	(	(	PUNCT
dti-1418	2	5	af	af	NOUN
dti-1418	2	6	)	)	PUNCT
dti-1418	2	7	is	be	AUX
dti-1418	2	8	the	the	DET
dti-1418	2	9	most	most	ADV
dti-1418	2	10	common	common	ADJ
dti-1418	2	11	sustained	sustained	ADJ
dti-1418	2	12	cardiac	cardiac	ADJ
dti-1418	2	13	arrhythmia	arrhythmia	NOUN
dti-1418	2	14	,	,	PUNCT
dti-1418	2	15	its	its	PRON
dti-1418	2	16	prevalence	prevalence	NOUN
dti-1418	2	17	increases	increase	VERB
dti-1418	2	18	dramatically	dramatically	ADV
dti-1418	2	19	with	with	ADP
dti-1418	2	20	age	age	NOUN
dti-1418	2	21	and	and	CCONJ
dti-1418	2	22	this	this	DET
dti-1418	2	23	prevalence	prevalence	NOUN
dti-1418	2	24	is	be	AUX
dti-1418	2	25	likely	likely	ADJ
dti-1418	2	26	to	to	PART
dti-1418	2	27	increase	increase	VERB
dti-1418	2	28	in	in	ADP
dti-1418	2	29	the	the	DET
dti-1418	2	30	next	next	ADJ
dti-1418	2	31	50	50	NUM
dti-1418	2	32	years.1,2	years.1,2	NOUN
dti-1418	2	33	moreover	moreover	ADV
dti-1418	2	34	,	,	PUNCT
dti-1418	2	35	af	af	PROPN
dti-1418	2	36	is	be	AUX
dti-1418	2	37	associated	associate	VERB
dti-1418	2	38	with	with	ADP
dti-1418	2	39	significant	significant	ADJ
dti-1418	2	40	mortality	mortality	NOUN
dti-1418	2	41	and	and	CCONJ
dti-1418	2	42	morbidity	morbidity	NOUN
dti-1418	2	43	,	,	PUNCT
dti-1418	2	44	and	and	CCONJ
dti-1418	2	45	one	one	NUM
dti-1418	2	46	in	in	ADP
dti-1418	2	47	five	five	NUM
dti-1418	2	48	of	of	ADP
dti-1418	2	49	all	all	DET
dti-1418	2	50	strokes	stroke	NOUN
dti-1418	2	51	is	be	AUX
dti-1418	2	52	attributed	attribute	VERB
dti-1418	2	53	to	to	ADP
dti-1418	2	54	af.3	af.3	PROPN
dti-1418	2	55	management	management	NOUN
dti-1418	2	56	of	of	ADP
dti-1418	2	57	af	af	PROPN
dti-1418	2	58	is	be	AUX
dti-1418	2	59	a	a	DET
dti-1418	2	60	multifaceted	multifaceted	ADJ
dti-1418	2	61	strategy	strategy	NOUN
dti-1418	2	62	:	:	PUNCT
dti-1418	2	63	control	control	NOUN
dti-1418	2	64	of	of	ADP
dti-1418	2	65	underlying	underlie	VERB
dti-1418	2	66	heart	heart	NOUN
dti-1418	2	67	disease	disease	NOUN
dti-1418	2	68	and	and	CCONJ
dti-1418	2	69	risk	risk	NOUN
dti-1418	2	70	factors	factor	NOUN
dti-1418	2	71	,	,	PUNCT
dti-1418	2	72	reversal	reversal	NOUN
dti-1418	2	73	of	of	ADP
dti-1418	2	74	arrhythmia	arrhythmia	NOUN
dti-1418	2	75	(	(	PUNCT
dti-1418	2	76	rhythm	rhythm	PROPN
dti-1418	2	77	control	control	PROPN
dti-1418	2	78	)	)	PUNCT
dti-1418	2	79	,	,	PUNCT
dti-1418	2	80	controlling	control	VERB
dti-1418	2	81	the	the	DET
dti-1418	2	82	rate	rate	NOUN
dti-1418	2	83	(	(	PUNCT
dti-1418	2	84	rate	rate	NOUN
dti-1418	2	85	control	control	NOUN
dti-1418	2	86	)	)	PUNCT
dti-1418	2	87	,	,	PUNCT
dti-1418	2	88	along	along	ADP
dti-1418	2	89	with	with	ADP
dti-1418	2	90	prevention	prevention	NOUN
dti-1418	2	91	of	of	ADP
dti-1418	2	92	associated	associated	ADJ
dti-1418	2	93	risk	risk	NOUN
dti-1418	2	94	of	of	ADP
dti-1418	2	95	thrombo	thrombo	NOUN
dti-1418	2	96	-	-	PUNCT
dti-1418	2	97	embolic	embolic	NOUN
dti-1418	2	98	events	event	NOUN
dti-1418	2	99	,	,	PUNCT
dti-1418	2	100	heart	heart	NOUN
dti-1418	2	101	failure	failure	NOUN
dti-1418	2	102	,	,	PUNCT
dti-1418	2	103	and	and	CCONJ
dti-1418	2	104	cardiac	cardiac	ADJ
dti-1418	2	105	ischemia.3,4	ischemia.3,4	ADJ
dti-1418	2	106	rate	rate	NOUN
dti-1418	2	107	or	or	CCONJ
dti-1418	2	108	rhythm	rhythm	NOUN
dti-1418	2	109	control	control	NOUN
dti-1418	2	110	often	often	ADV
dti-1418	2	111	constitutes	constitute	VERB
dti-1418	2	112	a	a	DET
dti-1418	2	113	dilemma	dilemma	NOUN
dti-1418	2	114	in	in	ADP
dti-1418	2	115	the	the	DET
dti-1418	2	116	management	management	NOUN
dti-1418	2	117	of	of	ADP
dti-1418	2	118	af,5	af,5	PROPN
dti-1418	2	119	and	and	CCONJ
dti-1418	2	120	although	although	SCONJ
dti-1418	2	121	clinical	clinical	ADJ
dti-1418	2	122	trials	trial	NOUN
dti-1418	2	123	showed	show	VERB
dti-1418	2	124	no	no	DET
dti-1418	2	125	major	major	ADJ
dti-1418	2	126	differences	difference	NOUN
dti-1418	2	127	in	in	ADP
dti-1418	2	128	outcomes	outcome	NOUN
dti-1418	2	129	in	in	ADP
dti-1418	2	130	rhythm	rhythm	NOUN
dti-1418	2	131	or	or	CCONJ
dti-1418	2	132	rate	rate	NOUN
dti-1418	2	133	control	control	NOUN
dti-1418	2	134	strategies	strategy	NOUN
dti-1418	2	135	,	,	PUNCT
dti-1418	2	136	rhythm	rhythm	PROPN
dti-1418	2	137	control	control	NOUN
dti-1418	2	138	is	be	AUX
dti-1418	2	139	advised	advise	VERB
dti-1418	2	140	in	in	ADP
dti-1418	2	141	recent	recent	ADJ
dti-1418	2	142	-	-	PUNCT
dti-1418	2	143	onset	onset	NOUN
dti-1418	2	144	af	af	NOUN
dti-1418	2	145	,	,	PUNCT
dti-1418	2	146	highly	highly	ADV
dti-1418	2	147	symptomatic	symptomatic	ADJ
dti-1418	2	148	patients	patient	NOUN
dti-1418	2	149	,	,	PUNCT
dti-1418	2	150	young	young	ADJ
dti-1418	2	151	and	and	CCONJ
dti-1418	2	152	active	active	ADJ
dti-1418	2	153	individuals.6	individuals.6	NOUN
dti-1418	2	154	moreover	moreover	ADV
dti-1418	2	155	,	,	PUNCT
dti-1418	2	156	rhythm	rhythm	PROPN
dti-1418	2	157	control	control	NOUN
dti-1418	2	158	provides	provide	VERB
dti-1418	2	159	better	well	ADJ
dti-1418	2	160	clinical	clinical	ADJ
dti-1418	2	161	benefit	benefit	NOUN
dti-1418	2	162	when	when	SCONJ
dti-1418	2	163	compared	compare	VERB
dti-1418	2	164	with	with	ADP
dti-1418	2	165	rate	rate	NOUN
dti-1418	2	166	control	control	NOUN
dti-1418	2	167	;	;	PUNCT
dti-1418	2	168	also	also	ADV
dti-1418	2	169	it	it	PRON
dti-1418	2	170	decreases	decrease	VERB
dti-1418	2	171	the	the	DET
dti-1418	2	172	risk	risk	NOUN
dti-1418	2	173	of	of	ADP
dti-1418	2	174	progression	progression	NOUN
dti-1418	2	175	to	to	ADP
dti-1418	2	176	permanent	permanent	ADJ
dti-1418	2	177	af.7	af.7	PROPN
dti-1418	2	178	rhythm	rhythm	PROPN
dti-1418	2	179	control	control	NOUN
dti-1418	2	180	can	can	AUX
dti-1418	2	181	be	be	AUX
dti-1418	2	182	achieved	achieve	VERB
dti-1418	2	183	either	either	CCONJ
dti-1418	2	184	by	by	ADP
dti-1418	2	185	electrical	electrical	ADJ
dti-1418	2	186	or	or	CCONJ
dti-1418	2	187	pharmacological	pharmacological	ADJ
dti-1418	2	188	cardioversion	cardioversion	NOUN
dti-1418	2	189	.	.	PUNCT
dti-1418	3	1	however	however	ADV
dti-1418	3	2	,	,	PUNCT
dti-1418	3	3	acute	acute	ADJ
dti-1418	3	4	cardioversion	cardioversion	NOUN
dti-1418	3	5	is	be	AUX
dti-1418	3	6	only	only	ADV
dti-1418	3	7	one	one	NUM
dti-1418	3	8	of	of	ADP
dti-1418	3	9	the	the	DET
dti-1418	3	10	strategies	strategy	NOUN
dti-1418	3	11	for	for	ADP
dti-1418	3	12	rhythm	rhythm	NOUN
dti-1418	3	13	control	control	NOUN
dti-1418	3	14	,	,	PUNCT
dti-1418	3	15	and	and	CCONJ
dti-1418	3	16	long	long	ADJ
dti-1418	3	17	-	-	PUNCT
dti-1418	3	18	term	term	NOUN
dti-1418	3	19	anti	anti	ADJ
dti-1418	3	20	-	-	ADJ
dti-1418	3	21	arrhythmic	arrhythmic	ADJ
dti-1418	3	22	drug	drug	NOUN
dti-1418	3	23	(	(	PUNCT
dti-1418	3	24	aad	aad	ADJ
dti-1418	3	25	)	)	PUNCT
dti-1418	3	26	therapy	therapy	NOUN
dti-1418	3	27	and	and	CCONJ
dti-1418	3	28	catheter	catheter	NOUN
dti-1418	3	29	ablation	ablation	NOUN
dti-1418	3	30	play	play	VERB
dti-1418	3	31	critical	critical	ADJ
dti-1418	3	32	roles	role	NOUN
dti-1418	3	33	in	in	ADP
dti-1418	3	34	this	this	DET
dti-1418	3	35	perspective	perspective	NOUN
dti-1418	3	36	.	.	PUNCT
dti-1418	4	1	vernakalant	vernakalant	NOUN
dti-1418	4	2	is	be	AUX
dti-1418	4	3	a	a	DET
dti-1418	4	4	relatively	relatively	ADV
dti-1418	4	5	novel	novel	ADJ
dti-1418	4	6	aad	aad	INTJ
dti-1418	4	7	,	,	PUNCT
dti-1418	4	8	available	available	ADJ
dti-1418	4	9	in	in	ADP
dti-1418	4	10	many	many	ADJ
dti-1418	4	11	parts	part	NOUN
dti-1418	4	12	of	of	ADP
dti-1418	4	13	the	the	DET
dti-1418	4	14	world	world	NOUN
dti-1418	4	15	;	;	PUNCT
dti-1418	4	16	it	it	PRON
dti-1418	4	17	has	have	AUX
dti-1418	4	18	been	be	AUX
dti-1418	4	19	approved	approve	VERB
dti-1418	4	20	for	for	ADP
dti-1418	4	21	pharmacological	pharmacological	ADJ
dti-1418	4	22	cardioversion	cardioversion	NOUN
dti-1418	4	23	of	of	ADP
dti-1418	4	24	recent	recent	ADJ
dti-1418	4	25	-	-	PUNCT
dti-1418	4	26	onset	onset	NOUN
dti-1418	4	27	af	af	PROPN
dti-1418	4	28	(	(	PUNCT
dti-1418	4	29	⩽7	⩽7	PROPN
dti-1418	4	30	days	day	NOUN
dti-1418	4	31	)	)	PUNCT
dti-1418	4	32	and	and	CCONJ
dti-1418	4	33	early	early	ADJ
dti-1418	4	34	(	(	PUNCT
dti-1418	4	35	⩽3	⩽3	NOUN
dti-1418	4	36	days	day	NOUN
dti-1418	4	37	)	)	PUNCT
dti-1418	4	38	post	post	VERB
dti-1418	4	39	cardiac	cardiac	ADJ
dti-1418	4	40	surgery	surgery	NOUN
dti-1418	4	41	af.8,9	af.8,9	PROPN
dti-1418	4	42	this	this	DET
dti-1418	4	43	review	review	NOUN
dti-1418	4	44	focuses	focus	VERB
dti-1418	4	45	on	on	ADP
dti-1418	4	46	the	the	DET
dti-1418	4	47	role	role	NOUN
dti-1418	4	48	and	and	CCONJ
dti-1418	4	49	benefit	benefit	NOUN
dti-1418	4	50	of	of	ADP
dti-1418	4	51	vernakalant	vernakalant	NOUN
dti-1418	4	52	in	in	ADP
dti-1418	4	53	the	the	DET
dti-1418	4	54	management	management	NOUN
dti-1418	4	55	recent	recent	ADJ
dti-1418	4	56	-	-	PUNCT
dti-1418	4	57	onset	onset	NOUN
dti-1418	4	58	af	af	NOUN
dti-1418	4	59	,	,	PUNCT
dti-1418	4	60	on	on	ADP
dti-1418	4	61	the	the	DET
dti-1418	4	62	light	light	NOUN
dti-1418	4	63	of	of	ADP
dti-1418	4	64	the	the	DET
dti-1418	4	65	current	current	ADJ
dti-1418	4	66	available	available	ADJ
dti-1418	4	67	scientific	scientific	ADJ
dti-1418	4	68	and	and	CCONJ
dti-1418	4	69	medical	medical	ADJ
dti-1418	4	70	literature	literature	NOUN
dti-1418	4	71	.	.	PUNCT
dti-1418	5	1	methodology	methodology	NOUN
dti-1418	5	2	through	through	ADP
dti-1418	5	3	a	a	DET
dti-1418	5	4	medline	medline	NOUN
dti-1418	5	5	/	/	SYM
dti-1418	5	6	pubmed	pubmed	PROPN
dti-1418	5	7	research	research	PROPN
dti-1418	5	8	,	,	PUNCT
dti-1418	5	9	we	we	PRON
dti-1418	5	10	used	use	VERB
dti-1418	5	11	separately	separately	ADV
dti-1418	5	12	the	the	DET
dti-1418	5	13	terms	term	NOUN
dti-1418	5	14	“	"	PUNCT
dti-1418	5	15	vernakalant	vernakalant	NOUN
dti-1418	5	16	,	,	PUNCT
dti-1418	5	17	”	"	PUNCT
dti-1418	5	18	“	"	PUNCT
dti-1418	5	19	rsd1235	rsd1235	VERB
dti-1418	5	20	,	,	PUNCT
dti-1418	5	21	”	"	PUNCT
dti-1418	5	22	“	"	PUNCT
dti-1418	5	23	atrial	atrial	ADJ
dti-1418	5	24	fibrillation	fibrillation	NOUN
dti-1418	5	25	.	.	PUNCT
dti-1418	5	26	”	"	PUNCT
dti-1418	6	1	the	the	DET
dti-1418	6	2	search	search	NOUN
dti-1418	6	3	started	start	VERB
dti-1418	6	4	from	from	ADP
dti-1418	6	5	2000	2000	NUM
dti-1418	6	6	,	,	PUNCT
dti-1418	6	7	selected	select	VERB
dti-1418	6	8	articles	article	NOUN
dti-1418	6	9	mainly	mainly	ADV
dti-1418	6	10	address	address	VERB
dti-1418	6	11	the	the	DET
dti-1418	6	12	clinical	clinical	ADJ
dti-1418	6	13	use	use	NOUN
dti-1418	6	14	,	,	PUNCT
dti-1418	6	15	benefit	benefit	NOUN
dti-1418	6	16	,	,	PUNCT
dti-1418	6	17	and	and	CCONJ
dti-1418	6	18	safety	safety	NOUN
dti-1418	6	19	rather	rather	ADV
dti-1418	6	20	than	than	ADP
dti-1418	6	21	the	the	DET
dti-1418	6	22	pure	pure	ADJ
dti-1418	6	23	pharmacodynamic	pharmacodynamic	ADJ
dti-1418	6	24	effect	effect	NOUN
dti-1418	6	25	.	.	PUNCT
dti-1418	7	1	editorial	editorial	ADJ
dti-1418	7	2	reports	report	NOUN
dti-1418	7	3	were	be	AUX
dti-1418	7	4	excluded	exclude	VERB
dti-1418	7	5	,	,	PUNCT
dti-1418	7	6	and	and	CCONJ
dti-1418	7	7	we	we	PRON
dti-1418	7	8	retained	retain	VERB
dti-1418	7	9	51	51	NUM
dti-1418	7	10	articles	article	NOUN
dti-1418	7	11	found	find	VERB
dti-1418	7	12	to	to	PART
dti-1418	7	13	be	be	AUX
dti-1418	7	14	relevant	relevant	ADJ
dti-1418	7	15	for	for	ADP
dti-1418	7	16	the	the	DET
dti-1418	7	17	study	study	NOUN
dti-1418	7	18	.	.	PUNCT
dti-1418	8	1	background	background	NOUN
dti-1418	8	2	the	the	DET
dti-1418	8	3	increasing	increase	VERB
dti-1418	8	4	prevalence	prevalence	NOUN
dti-1418	8	5	of	of	ADP
dti-1418	8	6	af	af	PROPN
dti-1418	8	7	in	in	ADP
dti-1418	8	8	the	the	DET
dti-1418	8	9	general	general	ADJ
dti-1418	8	10	population	population	NOUN
dti-1418	8	11	,	,	PUNCT
dti-1418	8	12	along	along	ADP
dti-1418	8	13	with	with	ADP
dti-1418	8	14	the	the	DET
dti-1418	8	15	increase	increase	NOUN
dti-1418	8	16	in	in	ADP
dti-1418	8	17	af	af	PROPN
dti-1418	8	18	complications	complication	NOUN
dti-1418	8	19	,	,	PUNCT
dti-1418	8	20	makes	make	VERB
dti-1418	8	21	the	the	DET
dti-1418	8	22	burden	burden	NOUN
dti-1418	8	23	of	of	ADP
dti-1418	8	24	af	af	PROPN
dti-1418	8	25	significantly	significantly	ADV
dti-1418	8	26	heavy	heavy	ADJ
dti-1418	8	27	as	as	ADP
dti-1418	8	28	a	a	DET
dti-1418	8	29	medical	medical	ADJ
dti-1418	8	30	condition	condition	NOUN
dti-1418	8	31	,	,	PUNCT
dti-1418	8	32	also	also	ADV
dti-1418	8	33	as	as	ADP
dti-1418	8	34	a	a	DET
dti-1418	8	35	socio	socio	NOUN
dti-1418	8	36	-	-	PUNCT
dti-1418	8	37	economical	economical	ADJ
dti-1418	8	38	issue	issue	NOUN
dti-1418	8	39	given	give	VERB
dti-1418	8	40	the	the	DET
dti-1418	8	41	cost	cost	NOUN
dti-1418	8	42	associated	associate	VERB
dti-1418	8	43	with	with	ADP
dti-1418	8	44	management	management	NOUN
dti-1418	8	45	,	,	PUNCT
dti-1418	8	46	prevention	prevention	NOUN
dti-1418	8	47	,	,	PUNCT
dti-1418	8	48	and	and	CCONJ
dti-1418	8	49	complications3,4	complications3,4	PROPN
dti-1418	8	50	moreover	moreover	ADV
dti-1418	8	51	,	,	PUNCT
dti-1418	8	52	despite	despite	SCONJ
dti-1418	8	53	all	all	DET
dti-1418	8	54	recent	recent	ADJ
dti-1418	8	55	therapeutic	therapeutic	ADJ
dti-1418	8	56	efforts	effort	NOUN
dti-1418	8	57	,	,	PUNCT
dti-1418	8	58	there	there	PRON
dti-1418	8	59	appears	appear	VERB
dti-1418	8	60	to	to	PART
dti-1418	8	61	be	be	AUX
dti-1418	8	62	in	in	ADP
dti-1418	8	63	most	most	ADJ
dti-1418	8	64	cases	case	NOUN
dti-1418	8	65	,	,	PUNCT
dti-1418	8	66	an	an	DET
dti-1418	8	67	inevitable	inevitable	ADJ
dti-1418	8	68	progression	progression	NOUN
dti-1418	8	69	from	from	ADP
dti-1418	8	70	paroxysmal	paroxysmal	ADJ
dti-1418	8	71	to	to	ADP
dti-1418	8	72	persistent	persistent	ADJ
dti-1418	8	73	and	and	CCONJ
dti-1418	8	74	then	then	ADV
dti-1418	8	75	to	to	ADP
dti-1418	8	76	permanent	permanent	ADJ
dti-1418	8	77	form.3	form.3	NOUN
dti-1418	8	78	there	there	PRON
dti-1418	8	79	is	be	VERB
dti-1418	8	80	still	still	ADV
dti-1418	8	81	some	some	DET
dti-1418	8	82	controversy	controversy	NOUN
dti-1418	8	83	regarding	regard	VERB
dti-1418	8	84	rate	rate	NOUN
dti-1418	8	85	vs	vs	ADP
dti-1418	8	86	rhythm	rhythm	PROPN
dti-1418	8	87	control	control	NOUN
dti-1418	8	88	in	in	ADP
dti-1418	8	89	af	af	PROPN
dti-1418	8	90	,	,	PUNCT
dti-1418	8	91	and	and	CCONJ
dti-1418	8	92	a	a	DET
dti-1418	8	93	wait	wait	VERB
dti-1418	8	94	-	-	PUNCT
dti-1418	8	95	and	and	CCONJ
dti-1418	8	96	-	-	PUNCT
dti-1418	8	97	see	see	VERB
dti-1418	8	98	approach	approach	NOUN
dti-1418	8	99	with	with	ADP
dti-1418	8	100	rate	rate	NOUN
dti-1418	8	101	control	control	NOUN
dti-1418	8	102	medication	medication	NOUN
dti-1418	8	103	may	may	AUX
dti-1418	8	104	be	be	AUX
dti-1418	8	105	adopted	adopt	VERB
dti-1418	8	106	for	for	ADP
dti-1418	8	107	patients	patient	NOUN
dti-1418	8	108	with	with	ADP
dti-1418	8	109	recent	recent	ADJ
dti-1418	8	110	-	-	PUNCT
dti-1418	8	111	onset	onset	NOUN
dti-1418	8	112	symptomatic	symptomatic	ADJ
dti-1418	8	113	af	af	NOUN
dti-1418	8	114	in	in	ADP
dti-1418	8	115	the	the	DET
dti-1418	8	116	emergency	emergency	NOUN
dti-1418	8	117	department	department	NOUN
dti-1418	8	118	,	,	PUNCT
dti-1418	8	119	especially	especially	ADV
dti-1418	8	120	that	that	DET
dti-1418	8	121	recent	recent	ADJ
dti-1418	8	122	-	-	PUNCT
dti-1418	8	123	onset	onset	NOUN
dti-1418	8	124	af	af	NOUN
dti-1418	8	125	resolves	resolve	NOUN
dti-1418	8	126	spontaneously	spontaneously	ADV
dti-1418	8	127	within	within	ADP
dti-1418	8	128	24	24	NUM
dti-1418	8	129	h	h	NOUN
dti-1418	8	130	in	in	ADP
dti-1418	8	131	more	more	ADJ
dti-1418	8	132	than	than	ADP
dti-1418	8	133	70	70	NUM
dti-1418	8	134	%	%	NOUN
dti-1418	8	135	of	of	ADP
dti-1418	8	136	the	the	DET
dti-1418	8	137	cases.10	cases.10	NOUN
dti-1418	8	138	moreover	moreover	ADV
dti-1418	8	139	,	,	PUNCT
dti-1418	8	140	the	the	DET
dti-1418	8	141	2016	2016	NUM
dti-1418	8	142	esc	esc	NOUN
dti-1418	8	143	guidelines	guideline	NOUN
dti-1418	8	144	stated	state	VERB
dti-1418	8	145	that	that	SCONJ
dti-1418	8	146	rhythm	rhythm	PROPN
dti-1418	8	147	control	control	NOUN
dti-1418	8	148	should	should	AUX
dti-1418	8	149	be	be	AUX
dti-1418	8	150	considered	consider	VERB
dti-1418	8	151	in	in	ADP
dti-1418	8	152	patients	patient	NOUN
dti-1418	8	153	who	who	PRON
dti-1418	8	154	remain	remain	VERB
dti-1418	8	155	symptomatic	symptomatic	ADJ
dti-1418	8	156	despite	despite	SCONJ
dti-1418	8	157	rate	rate	NOUN
dti-1418	8	158	control	control	NOUN
dti-1418	8	159	approach.3	approach.3	ADP
dti-1418	8	160	however	however	ADV
dti-1418	8	161	,	,	PUNCT
dti-1418	8	162	there	there	PRON
dti-1418	8	163	is	be	VERB
dti-1418	8	164	a	a	DET
dti-1418	8	165	clinical	clinical	ADJ
dti-1418	8	166	trend	trend	NOUN
dti-1418	8	167	or	or	CCONJ
dti-1418	8	168	opinion	opinion	NOUN
dti-1418	8	169	that	that	SCONJ
dti-1418	8	170	rhythm	rhythm	PROPN
dti-1418	8	171	control	control	NOUN
dti-1418	8	172	is	be	AUX
dti-1418	8	173	better	well	ADJ
dti-1418	8	174	to	to	PART
dti-1418	8	175	prevent	prevent	VERB
dti-1418	8	176	atrial	atrial	ADJ
dti-1418	8	177	remodeling	remodeling	NOUN
dti-1418	8	178	and	and	CCONJ
dti-1418	8	179	progression	progression	NOUN
dti-1418	8	180	from	from	ADP
dti-1418	8	181	paroxysmal	paroxysmal	ADJ
dti-1418	8	182	or	or	CCONJ
dti-1418	8	183	persistent	persistent	ADJ
dti-1418	8	184	to	to	ADP
dti-1418	8	185	permanent	permanent	ADJ
dti-1418	8	186	af.6,7	af.6,7	NOUN
dti-1418	8	187	rhythm	rhythm	NOUN
dti-1418	8	188	control	control	NOUN
dti-1418	8	189	may	may	AUX
dti-1418	8	190	be	be	AUX
dti-1418	8	191	achieved	achieve	VERB
dti-1418	8	192	via	via	ADP
dti-1418	8	193	either	either	CCONJ
dti-1418	8	194	electrical	electrical	ADJ
dti-1418	8	195	or	or	CCONJ
dti-1418	8	196	pharmacological	pharmacological	ADJ
dti-1418	8	197	cardioversion	cardioversion	NOUN
dti-1418	8	198	;	;	PUNCT
dti-1418	8	199	in	in	ADP
dti-1418	8	200	this	this	DET
dti-1418	8	201	regard	regard	NOUN
dti-1418	8	202	,	,	PUNCT
dti-1418	8	203	physician	physician	NOUN
dti-1418	8	204	preference	preference	NOUN
dti-1418	8	205	plays	play	VERB
dti-1418	8	206	a	a	DET
dti-1418	8	207	role	role	NOUN
dti-1418	8	208	in	in	ADP
dti-1418	8	209	the	the	DET
dti-1418	8	210	vernakalant	vernakalant	NOUN
dti-1418	8	211	in	in	ADP
dti-1418	8	212	atrial	atrial	ADJ
dti-1418	8	213	fibrillation	fibrillation	NOUN
dti-1418	8	214	:	:	PUNCT
dti-1418	8	215	a	a	DET
dti-1418	8	216	relatively	relatively	ADV
dti-1418	8	217	new	new	ADJ
dti-1418	8	218	weapon	weapon	NOUN
dti-1418	8	219	in	in	ADP
dti-1418	8	220	the	the	DET
dti-1418	8	221	armamentarium	armamentarium	NOUN
dti-1418	8	222	against	against	ADP
dti-1418	8	223	an	an	DET
dti-1418	8	224	old	old	ADJ
dti-1418	8	225	enemy	enemy	NOUN
dti-1418	8	226	antoine	antoine	PROPN
dti-1418	8	227	kossaify	kossaify	VERB
dti-1418	8	228	electrophysiology	electrophysiology	NOUN
dti-1418	8	229	unit	unit	NOUN
dti-1418	8	230	,	,	PUNCT
dti-1418	8	231	cardiology	cardiology	NOUN
dti-1418	8	232	division	division	NOUN
dti-1418	8	233	,	,	PUNCT
dti-1418	8	234	holy	holy	PROPN
dti-1418	8	235	spirit	spirit	PROPN
dti-1418	8	236	university	university	PROPN
dti-1418	8	237	of	of	ADP
dti-1418	8	238	kaslik	kaslik	PROPN
dti-1418	8	239	(	(	PUNCT
dti-1418	8	240	usek	usek	PROPN
dti-1418	8	241	)	)	PUNCT
dti-1418	8	242	and	and	CCONJ
dti-1418	8	243	university	university	NOUN
dti-1418	8	244	hospital	hospital	NOUN
dti-1418	8	245	notre	notre	PROPN
dti-1418	8	246	dame	dame	PROPN
dti-1418	8	247	des	des	PROPN
dti-1418	8	248	secours	secours	PROPN
dti-1418	8	249	,	,	PUNCT
dti-1418	8	250	byblos	byblos	PROPN
dti-1418	8	251	,	,	PUNCT
dti-1418	8	252	lebanon	lebanon	PROPN
dti-1418	8	253	.	.	PUNCT
dti-1418	9	1	abstract	abstract	ADJ
dti-1418	9	2	:	:	PUNCT
dti-1418	9	3	atrial	atrial	ADJ
dti-1418	9	4	fibrillation	fibrillation	NOUN
dti-1418	9	5	is	be	AUX
dti-1418	9	6	the	the	DET
dti-1418	9	7	most	most	ADV
dti-1418	9	8	common	common	ADJ
dti-1418	9	9	sustained	sustained	ADJ
dti-1418	9	10	cardiac	cardiac	ADJ
dti-1418	9	11	arrhythmia	arrhythmia	NOUN
dti-1418	9	12	,	,	PUNCT
dti-1418	9	13	and	and	CCONJ
dti-1418	9	14	its	its	PRON
dti-1418	9	15	prevalence	prevalence	NOUN
dti-1418	9	16	is	be	AUX
dti-1418	9	17	increasing	increase	VERB
dti-1418	9	18	with	with	ADP
dti-1418	9	19	age	age	NOUN
dti-1418	9	20	;	;	PUNCT
dti-1418	9	21	also	also	ADV
dti-1418	9	22	it	it	PRON
dti-1418	9	23	is	be	AUX
dti-1418	9	24	associated	associate	VERB
dti-1418	9	25	with	with	ADP
dti-1418	9	26	significant	significant	ADJ
dti-1418	9	27	morbidity	morbidity	NOUN
dti-1418	9	28	and	and	CCONJ
dti-1418	9	29	mortality	mortality	NOUN
dti-1418	9	30	.	.	PUNCT
dti-1418	10	1	rhythm	rhythm	PROPN
dti-1418	10	2	control	control	NOUN
dti-1418	10	3	is	be	AUX
dti-1418	10	4	advised	advise	VERB
dti-1418	10	5	in	in	ADP
dti-1418	10	6	recent	recent	ADJ
dti-1418	10	7	-	-	PUNCT
dti-1418	10	8	onset	onset	ADJ
dti-1418	10	9	atrial	atrial	ADJ
dti-1418	10	10	fibrillation	fibrillation	NOUN
dti-1418	10	11	,	,	PUNCT
dti-1418	10	12	and	and	CCONJ
dti-1418	10	13	in	in	ADP
dti-1418	10	14	highly	highly	ADV
dti-1418	10	15	symptomatic	symptomatic	ADJ
dti-1418	10	16	patients	patient	NOUN
dti-1418	10	17	,	,	PUNCT
dti-1418	10	18	also	also	ADV
dti-1418	10	19	in	in	ADP
dti-1418	10	20	young	young	ADJ
dti-1418	10	21	and	and	CCONJ
dti-1418	10	22	active	active	ADJ
dti-1418	10	23	individuals	individual	NOUN
dti-1418	10	24	.	.	PUNCT
dti-1418	11	1	moreover	moreover	ADV
dti-1418	11	2	,	,	PUNCT
dti-1418	11	3	rhythm	rhythm	PROPN
dti-1418	11	4	control	control	NOUN
dti-1418	11	5	is	be	AUX
dti-1418	11	6	associated	associate	VERB
dti-1418	11	7	with	with	ADP
dti-1418	11	8	lower	low	ADJ
dti-1418	11	9	incidence	incidence	NOUN
dti-1418	11	10	of	of	ADP
dti-1418	11	11	progression	progression	NOUN
dti-1418	11	12	to	to	ADP
dti-1418	11	13	permanent	permanent	ADJ
dti-1418	11	14	atrial	atrial	ADJ
dti-1418	11	15	fibrillation	fibrillation	NOUN
dti-1418	11	16	.	.	PUNCT
dti-1418	12	1	vernakalant	vernakalant	NOUN
dti-1418	12	2	is	be	AUX
dti-1418	12	3	a	a	DET
dti-1418	12	4	relatively	relatively	ADV
dti-1418	12	5	new	new	ADJ
dti-1418	12	6	anti	anti	ADJ
dti-1418	12	7	-	-	ADJ
dti-1418	12	8	arrhythmic	arrhythmic	ADJ
dti-1418	12	9	drug	drug	NOUN
dti-1418	12	10	that	that	PRON
dti-1418	12	11	showed	show	VERB
dti-1418	12	12	efficacy	efficacy	NOUN
dti-1418	12	13	and	and	CCONJ
dti-1418	12	14	safety	safety	NOUN
dti-1418	12	15	in	in	ADP
dti-1418	12	16	recent	recent	ADJ
dti-1418	12	17	-	-	PUNCT
dti-1418	12	18	onset	onset	ADJ
dti-1418	12	19	atrial	atrial	ADJ
dti-1418	12	20	fibrillation	fibrillation	NOUN
dti-1418	12	21	.	.	PUNCT
dti-1418	13	1	vernakalant	vernakalant	NOUN
dti-1418	13	2	is	be	AUX
dti-1418	13	3	indicated	indicate	VERB
dti-1418	13	4	in	in	ADP
dti-1418	13	5	atrial	atrial	ADJ
dti-1418	13	6	fibrillation	fibrillation	NOUN
dti-1418	13	7	(	(	PUNCT
dti-1418	13	8	⩽7	⩽7	X
dti-1418	13	9	days	day	NOUN
dti-1418	13	10	)	)	PUNCT
dti-1418	13	11	in	in	ADP
dti-1418	13	12	patients	patient	NOUN
dti-1418	13	13	with	with	ADP
dti-1418	13	14	no	no	DET
dti-1418	13	15	heart	heart	NOUN
dti-1418	13	16	disease	disease	NOUN
dti-1418	13	17	(	(	PUNCT
dti-1418	13	18	class	class	NOUN
dti-1418	13	19	i	i	PROPN
dti-1418	13	20	,	,	PUNCT
dti-1418	13	21	level	level	VERB
dti-1418	13	22	a	a	NOUN
dti-1418	13	23	)	)	PUNCT
dti-1418	13	24	or	or	CCONJ
dti-1418	13	25	in	in	ADP
dti-1418	13	26	patients	patient	NOUN
dti-1418	13	27	with	with	ADP
dti-1418	13	28	mild	mild	ADJ
dti-1418	13	29	or	or	CCONJ
dti-1418	13	30	moderate	moderate	ADJ
dti-1418	13	31	structural	structural	ADJ
dti-1418	13	32	heart	heart	NOUN
dti-1418	13	33	disease	disease	NOUN
dti-1418	13	34	(	(	PUNCT
dti-1418	13	35	class	class	NOUN
dti-1418	13	36	iib	iib	NOUN
dti-1418	13	37	,	,	PUNCT
dti-1418	13	38	level	level	NOUN
dti-1418	13	39	b	b	NOUN
dti-1418	13	40	)	)	PUNCT
dti-1418	13	41	.	.	PUNCT
dti-1418	14	1	moreover	moreover	ADV
dti-1418	14	2	,	,	PUNCT
dti-1418	14	3	vernakalant	vernakalant	NOUN
dti-1418	14	4	may	may	AUX
dti-1418	14	5	be	be	AUX
dti-1418	14	6	considered	consider	VERB
dti-1418	14	7	for	for	ADP
dti-1418	14	8	recent	recent	ADJ
dti-1418	14	9	-	-	PUNCT
dti-1418	14	10	onset	onset	ADJ
dti-1418	14	11	atrial	atrial	ADJ
dti-1418	14	12	fibrillation	fibrillation	NOUN
dti-1418	14	13	(	(	PUNCT
dti-1418	14	14	⩽3	⩽3	NOUN
dti-1418	14	15	days	day	NOUN
dti-1418	14	16	)	)	PUNCT
dti-1418	14	17	post	post	VERB
dti-1418	14	18	cardiac	cardiac	ADJ
dti-1418	14	19	surgery	surgery	NOUN
dti-1418	14	20	(	(	PUNCT
dti-1418	14	21	class	class	NOUN
dti-1418	14	22	iib	iib	NOUN
dti-1418	14	23	,	,	PUNCT
dti-1418	14	24	level	level	NOUN
dti-1418	14	25	b	b	NOUN
dti-1418	14	26	)	)	PUNCT
dti-1418	14	27	.	.	PUNCT
dti-1418	15	1	although	although	SCONJ
dti-1418	15	2	it	it	PRON
dti-1418	15	3	is	be	AUX
dti-1418	15	4	mainly	mainly	ADV
dti-1418	15	5	indicated	indicate	VERB
dti-1418	15	6	in	in	ADP
dti-1418	15	7	patients	patient	NOUN
dti-1418	15	8	with	with	ADP
dti-1418	15	9	recent	recent	ADJ
dti-1418	15	10	-	-	PUNCT
dti-1418	15	11	onset	onset	ADJ
dti-1418	15	12	atrial	atrial	ADJ
dti-1418	15	13	fibrillation	fibrillation	NOUN
dti-1418	15	14	and	and	CCONJ
dti-1418	15	15	with	with	ADP
dti-1418	15	16	no	no	DET
dti-1418	15	17	structural	structural	ADJ
dti-1418	15	18	heart	heart	NOUN
dti-1418	15	19	disease	disease	NOUN
dti-1418	15	20	,	,	PUNCT
dti-1418	15	21	it	it	PRON
dti-1418	15	22	can	can	AUX
dti-1418	15	23	be	be	AUX
dti-1418	15	24	given	give	VERB
dti-1418	15	25	in	in	ADP
dti-1418	15	26	moderate	moderate	ADJ
dti-1418	15	27	stable	stable	ADJ
dti-1418	15	28	cardiac	cardiac	ADJ
dti-1418	15	29	disease	disease	NOUN
dti-1418	15	30	as	as	ADP
dti-1418	15	31	alternative	alternative	ADJ
dti-1418	15	32	to	to	ADP
dti-1418	15	33	amiodarone	amiodarone	NOUN
dti-1418	15	34	.	.	PUNCT
dti-1418	16	1	similarly	similarly	ADV
dti-1418	16	2	to	to	ADP
dti-1418	16	3	electrical	electrical	ADJ
dti-1418	16	4	cardioversion	cardioversion	NOUN
dti-1418	16	5	,	,	PUNCT
dti-1418	16	6	pharmacological	pharmacological	ADJ
dti-1418	16	7	cardioversion	cardioversion	NOUN
dti-1418	16	8	requires	require	VERB
dti-1418	16	9	a	a	DET
dti-1418	16	10	minimal	minimal	ADJ
dti-1418	16	11	evaluation	evaluation	NOUN
dti-1418	16	12	and	and	CCONJ
dti-1418	16	13	cardioversion	cardioversion	NOUN
dti-1418	16	14	should	should	AUX
dti-1418	16	15	be	be	AUX
dti-1418	16	16	included	include	VERB
dti-1418	16	17	in	in	ADP
dti-1418	16	18	a	a	DET
dti-1418	16	19	comprehensive	comprehensive	ADJ
dti-1418	16	20	management	management	NOUN
dti-1418	16	21	strategy	strategy	NOUN
dti-1418	16	22	for	for	ADP
dti-1418	16	23	better	well	ADJ
dti-1418	16	24	outcome	outcome	NOUN
dti-1418	16	25	.	.	PUNCT
dti-1418	17	1	keywords	keyword	NOUN
dti-1418	17	2	:	:	PUNCT
dti-1418	17	3	vernakalant	vernakalant	NOUN
dti-1418	17	4	,	,	PUNCT
dti-1418	17	5	atrial	atrial	ADJ
dti-1418	17	6	,	,	PUNCT
dti-1418	17	7	fibrillation	fibrillation	NOUN
dti-1418	17	8	,	,	PUNCT
dti-1418	17	9	pharmaceutical	pharmaceutical	NOUN
dti-1418	17	10	,	,	PUNCT
dti-1418	17	11	cardioversion	cardioversion	NOUN
dti-1418	17	12	received	receive	VERB
dti-1418	17	13	:	:	PUNCT
dti-1418	17	14	april	april	PROPN
dti-1418	17	15	23	23	NUM
dti-1418	17	16	,	,	PUNCT
dti-1418	17	17	2019	2019	NUM
dti-1418	17	18	.	.	PUNCT
dti-1418	18	1	accepted	accept	VERB
dti-1418	18	2	:	:	PUNCT
dti-1418	18	3	june	june	PROPN
dti-1418	18	4	3	3	NUM
dti-1418	18	5	,	,	PUNCT
dti-1418	18	6	2019	2019	NUM
dti-1418	18	7	.	.	PUNCT
dti-1418	19	1	type	type	NOUN
dti-1418	19	2	:	:	PUNCT
dti-1418	19	3	review	review	NOUN
dti-1418	19	4	funding	funding	NOUN
dti-1418	19	5	:	:	PUNCT
dti-1418	19	6	the	the	DET
dti-1418	19	7	author(s	author(s	PROPN
dti-1418	19	8	)	)	PUNCT
dti-1418	19	9	received	receive	VERB
dti-1418	19	10	no	no	DET
dti-1418	19	11	financial	financial	ADJ
dti-1418	19	12	support	support	NOUN
dti-1418	19	13	for	for	ADP
dti-1418	19	14	the	the	DET
dti-1418	19	15	research	research	NOUN
dti-1418	19	16	,	,	PUNCT
dti-1418	19	17	authorship	authorship	NOUN
dti-1418	19	18	,	,	PUNCT
dti-1418	19	19	and/or	and/or	CCONJ
dti-1418	19	20	publication	publication	NOUN
dti-1418	19	21	of	of	ADP
dti-1418	19	22	this	this	DET
dti-1418	19	23	article	article	NOUN
dti-1418	19	24	.	.	PUNCT
dti-1418	20	1	declaration	declaration	NOUN
dti-1418	20	2	of	of	ADP
dti-1418	20	3	conflicting	conflicting	ADJ
dti-1418	20	4	interests	interest	NOUN
dti-1418	20	5	:	:	PUNCT
dti-1418	20	6	the	the	DET
dti-1418	20	7	author(s	author(s	NOUN
dti-1418	20	8	)	)	PUNCT
dti-1418	20	9	declared	declare	VERB
dti-1418	20	10	no	no	DET
dti-1418	20	11	potential	potential	ADJ
dti-1418	20	12	conflicts	conflict	NOUN
dti-1418	20	13	of	of	ADP
dti-1418	20	14	interest	interest	NOUN
dti-1418	20	15	with	with	ADP
dti-1418	20	16	respect	respect	NOUN
dti-1418	20	17	to	to	ADP
dti-1418	20	18	the	the	DET
dti-1418	20	19	research	research	NOUN
dti-1418	20	20	,	,	PUNCT
dti-1418	20	21	authorship	authorship	NOUN
dti-1418	20	22	,	,	PUNCT
dti-1418	20	23	and/or	and/or	CCONJ
dti-1418	20	24	publication	publication	NOUN
dti-1418	20	25	of	of	ADP
dti-1418	20	26	this	this	DET
dti-1418	20	27	article	article	NOUN
dti-1418	20	28	.	.	PUNCT
dti-1418	21	1	corresponding	correspond	VERB
dti-1418	21	2	author	author	NOUN
dti-1418	21	3	:	:	PUNCT
dti-1418	21	4	antoine	antoine	PROPN
dti-1418	21	5	kossaify	kossaify	VERB
dti-1418	21	6	,	,	PUNCT
dti-1418	21	7	electrophysiology	electrophysiology	NOUN
dti-1418	21	8	unit	unit	NOUN
dti-1418	21	9	,	,	PUNCT
dti-1418	21	10	cardiology	cardiology	NOUN
dti-1418	21	11	division	division	NOUN
dti-1418	21	12	,	,	PUNCT
dti-1418	21	13	holy	holy	PROPN
dti-1418	21	14	spirit	spirit	PROPN
dti-1418	21	15	university	university	PROPN
dti-1418	21	16	of	of	ADP
dti-1418	21	17	kaslik	kaslik	PROPN
dti-1418	21	18	(	(	PUNCT
dti-1418	21	19	usek	usek	PROPN
dti-1418	21	20	)	)	PUNCT
dti-1418	21	21	and	and	CCONJ
dti-1418	21	22	university	university	NOUN
dti-1418	21	23	hospital	hospital	NOUN
dti-1418	21	24	notre	notre	PROPN
dti-1418	21	25	dame	dame	PROPN
dti-1418	21	26	des	des	PROPN
dti-1418	21	27	secours	secours	PROPN
dti-1418	21	28	,	,	PUNCT
dti-1418	21	29	byblos	byblos	PROPN
dti-1418	21	30	,	,	PUNCT
dti-1418	21	31	p.o	p.o	PROPN
dti-1418	21	32	box	box	PROPN
dti-1418	21	33	3	3	NUM
dti-1418	21	34	,	,	PUNCT
dti-1418	21	35	zip	zip	NOUN
dti-1418	21	36	12345	12345	NUM
dti-1418	21	37	;	;	PUNCT
dti-1418	21	38	jbeil	jbeil	PROPN
dti-1418	21	39	,	,	PUNCT
dti-1418	21	40	lebanon	lebanon	PROPN
dti-1418	21	41	.	.	PUNCT
dti-1418	21	42	email	email	NOUN
dti-1418	21	43	:	:	PUNCT
dti-1418	21	44	antoinekossaify@yahoo.com	antoinekossaify@yahoo.com	X
dti-1418	21	45	861114	861114	NUM
dti-1418	22	1	dti0010.1177/1177392819861114drug	dti0010.1177/1177392819861114drug	VERB
dti-1418	22	2	target	target	NOUN
dti-1418	22	3	insightskossaify	insightskossaify	VERB
dti-1418	22	4	review	review	NOUN
dti-1418	22	5	-	-	PUNCT
dti-1418	22	6	article2019	article2019	PROPN
dti-1418	22	7	https://uk.sagepub.com/en-gb/journals-permissions	https://uk.sagepub.com/en-gb/journals-permission	NOUN
dti-1418	22	8	mailto:antoinekossaify@yahoo.com	mailto:antoinekossaify@yahoo.com	NOUN
dti-1418	22	9	2	2	NUM
dti-1418	22	10	drug	drug	NOUN
dti-1418	22	11	target	target	NOUN
dti-1418	22	12	insights	insight	NOUN
dti-1418	22	13	decision	decision	NOUN
dti-1418	22	14	process	process	NOUN
dti-1418	22	15	,	,	PUNCT
dti-1418	22	16	and	and	CCONJ
dti-1418	22	17	this	this	DET
dti-1418	22	18	decision	decision	NOUN
dti-1418	22	19	varies	vary	VERB
dti-1418	22	20	depending	depend	VERB
dti-1418	22	21	on	on	ADP
dti-1418	22	22	previous	previous	ADJ
dti-1418	22	23	experience	experience	NOUN
dti-1418	22	24	,	,	PUNCT
dti-1418	22	25	local	local	ADJ
dti-1418	22	26	tradition	tradition	NOUN
dti-1418	22	27	,	,	PUNCT
dti-1418	22	28	and	and	CCONJ
dti-1418	22	29	regulations	regulation	NOUN
dti-1418	22	30	.	.	PUNCT
dti-1418	23	1	of	of	ADP
dti-1418	23	2	note	note	NOUN
dti-1418	23	3	,	,	PUNCT
dti-1418	23	4	pharmacological	pharmacological	ADJ
dti-1418	23	5	cardioversion	cardioversion	NOUN
dti-1418	23	6	is	be	AUX
dti-1418	23	7	preferred	prefer	VERB
dti-1418	23	8	as	as	ADP
dti-1418	23	9	a	a	DET
dti-1418	23	10	first	first	ADJ
dti-1418	23	11	-	-	PUNCT
dti-1418	23	12	line	line	NOUN
dti-1418	23	13	approach	approach	NOUN
dti-1418	23	14	in	in	ADP
dti-1418	23	15	patients	patient	NOUN
dti-1418	23	16	who	who	PRON
dti-1418	23	17	tolerate	tolerate	VERB
dti-1418	23	18	their	their	PRON
dti-1418	23	19	arrhythmia	arrhythmia	NOUN
dti-1418	23	20	especially	especially	ADV
dti-1418	23	21	when	when	SCONJ
dti-1418	23	22	no	no	DET
dti-1418	23	23	hemodynamic	hemodynamic	ADJ
dti-1418	23	24	compromise	compromise	NOUN
dti-1418	23	25	is	be	AUX
dti-1418	23	26	present.3	present.3	PROPN
dti-1418	23	27	the	the	DET
dti-1418	23	28	advantages	advantage	NOUN
dti-1418	23	29	of	of	ADP
dti-1418	23	30	pharmacological	pharmacological	ADJ
dti-1418	23	31	cardioversion	cardioversion	NOUN
dti-1418	23	32	are	be	AUX
dti-1418	23	33	that	that	SCONJ
dti-1418	23	34	there	there	PRON
dti-1418	23	35	is	be	VERB
dti-1418	23	36	no	no	DET
dti-1418	23	37	need	need	NOUN
dti-1418	23	38	for	for	ADP
dti-1418	23	39	general	general	ADJ
dti-1418	23	40	anesthesia	anesthesia	NOUN
dti-1418	23	41	or	or	CCONJ
dti-1418	23	42	conscious	conscious	ADJ
dti-1418	23	43	sedation	sedation	NOUN
dti-1418	23	44	with	with	ADP
dti-1418	23	45	fasting	fasting	NOUN
dti-1418	23	46	,	,	PUNCT
dti-1418	23	47	along	along	ADP
dti-1418	23	48	with	with	ADP
dti-1418	23	49	potentially	potentially	ADV
dti-1418	23	50	lower	low	ADJ
dti-1418	23	51	psychological	psychological	ADJ
dti-1418	23	52	impact	impact	NOUN
dti-1418	23	53	related	relate	VERB
dti-1418	23	54	to	to	ADP
dti-1418	23	55	electrical	electrical	ADJ
dti-1418	23	56	cardioversion	cardioversion	NOUN
dti-1418	23	57	and	and	CCONJ
dti-1418	23	58	arguably	arguably	ADV
dti-1418	23	59	a	a	DET
dti-1418	23	60	lower	low	ADJ
dti-1418	23	61	risk	risk	NOUN
dti-1418	23	62	of	of	ADP
dti-1418	23	63	immediate	immediate	ADJ
dti-1418	23	64	recurrence	recurrence	NOUN
dti-1418	23	65	;	;	PUNCT
dti-1418	23	66	the	the	DET
dti-1418	23	67	lower	low	ADJ
dti-1418	23	68	risk	risk	NOUN
dti-1418	23	69	of	of	ADP
dti-1418	23	70	immediate	immediate	ADJ
dti-1418	23	71	recurrence	recurrence	NOUN
dti-1418	23	72	is	be	AUX
dti-1418	23	73	probably	probably	ADV
dti-1418	23	74	related	relate	VERB
dti-1418	23	75	to	to	ADP
dti-1418	23	76	better	well	ADJ
dti-1418	23	77	aad	aad	NOUN
dti-1418	23	78	loading	loading	NOUN
dti-1418	23	79	ordinarily	ordinarily	ADV
dti-1418	23	80	implemented	implement	VERB
dti-1418	23	81	in	in	ADP
dti-1418	23	82	pharmacological	pharmacological	ADJ
dti-1418	23	83	cardioversion	cardioversion	NOUN
dti-1418	23	84	,	,	PUNCT
dti-1418	23	85	providing	provide	VERB
dti-1418	23	86	a	a	DET
dti-1418	23	87	significant	significant	ADJ
dti-1418	23	88	efficacy	efficacy	NOUN
dti-1418	23	89	immediately	immediately	ADV
dti-1418	23	90	and	and	CCONJ
dti-1418	23	91	for	for	ADP
dti-1418	23	92	the	the	DET
dti-1418	23	93	subsequent	subsequent	ADJ
dti-1418	23	94	hours	hour	NOUN
dti-1418	23	95	and	and	CCONJ
dti-1418	23	96	days	day	NOUN
dti-1418	23	97	following	follow	VERB
dti-1418	23	98	cardioversion.9	cardioversion.9	NOUN
dti-1418	23	99	pharmacological	pharmacological	NOUN
dti-1418	23	100	technique	technique	NOUN
dti-1418	23	101	using	use	VERB
dti-1418	23	102	the	the	DET
dti-1418	23	103	“	"	PUNCT
dti-1418	23	104	pill	pill	NOUN
dti-1418	23	105	-	-	PUNCT
dti-1418	23	106	in	in	ADP
dti-1418	23	107	-	-	PUNCT
dti-1418	23	108	the	the	DET
dti-1418	23	109	-	-	PUNCT
dti-1418	23	110	pocket	pocket	NOUN
dti-1418	23	111	”	"	PUNCT
dti-1418	23	112	(	(	PUNCT
dti-1418	23	113	ie	ie	X
dti-1418	23	114	,	,	PUNCT
dti-1418	23	115	flecainide	flecainide	PROPN
dti-1418	23	116	,	,	PUNCT
dti-1418	23	117	propafenone	propafenone	NOUN
dti-1418	23	118	,	,	PUNCT
dti-1418	23	119	sotalol	sotalol	VERB
dti-1418	23	120	)	)	PUNCT
dti-1418	23	121	as	as	ADP
dti-1418	23	122	a	a	DET
dti-1418	23	123	prompt	prompt	ADJ
dti-1418	23	124	method	method	NOUN
dti-1418	23	125	to	to	PART
dti-1418	23	126	terminate	terminate	VERB
dti-1418	23	127	paroxysmal	paroxysmal	ADJ
dti-1418	23	128	af	af	PROPN
dti-1418	23	129	is	be	AUX
dti-1418	23	130	debated	debate	VERB
dti-1418	23	131	.	.	PUNCT
dti-1418	24	1	use	use	NOUN
dti-1418	24	2	and	and	CCONJ
dti-1418	24	3	success	success	NOUN
dti-1418	24	4	of	of	ADP
dti-1418	24	5	the	the	DET
dti-1418	24	6	“	"	PUNCT
dti-1418	24	7	pill	pill	NOUN
dti-1418	24	8	-	-	PUNCT
dti-1418	24	9	in	in	ADP
dti-1418	24	10	-	-	PUNCT
dti-1418	24	11	the	the	DET
dti-1418	24	12	-	-	PUNCT
dti-1418	24	13	pocket	pocket	NOUN
dti-1418	24	14	”	"	PUNCT
dti-1418	24	15	technique	technique	NOUN
dti-1418	24	16	depends	depend	VERB
dti-1418	24	17	on	on	ADP
dti-1418	24	18	the	the	DET
dti-1418	24	19	context	context	NOUN
dti-1418	24	20	,	,	PUNCT
dti-1418	24	21	urgency	urgency	NOUN
dti-1418	24	22	of	of	ADP
dti-1418	24	23	the	the	DET
dti-1418	24	24	situation	situation	NOUN
dti-1418	24	25	,	,	PUNCT
dti-1418	24	26	patient	patient	ADJ
dti-1418	24	27	compliance	compliance	NOUN
dti-1418	24	28	,	,	PUNCT
dti-1418	24	29	physician	physician	NOUN
dti-1418	24	30	experience	experience	NOUN
dti-1418	24	31	,	,	PUNCT
dti-1418	24	32	availability	availability	NOUN
dti-1418	24	33	of	of	ADP
dti-1418	24	34	the	the	DET
dti-1418	24	35	drug	drug	NOUN
dti-1418	24	36	,	,	PUNCT
dti-1418	24	37	underlying	underlie	VERB
dti-1418	24	38	heart	heart	NOUN
dti-1418	24	39	disease	disease	NOUN
dti-1418	24	40	,	,	PUNCT
dti-1418	24	41	and	and	CCONJ
dti-1418	24	42	so	so	ADV
dti-1418	24	43	on.11	on.11	NOUN
dti-1418	24	44	in	in	ADP
dti-1418	24	45	this	this	DET
dti-1418	24	46	respect	respect	NOUN
dti-1418	24	47	,	,	PUNCT
dti-1418	24	48	there	there	PRON
dti-1418	24	49	is	be	VERB
dti-1418	24	50	currently	currently	ADV
dti-1418	24	51	insufficient	insufficient	ADJ
dti-1418	24	52	evidence	evidence	NOUN
dti-1418	24	53	to	to	PART
dti-1418	24	54	support	support	VERB
dti-1418	24	55	a	a	DET
dti-1418	24	56	recommendation	recommendation	NOUN
dti-1418	24	57	for	for	ADP
dti-1418	24	58	the	the	DET
dti-1418	24	59	use	use	NOUN
dti-1418	24	60	of	of	ADP
dti-1418	24	61	the	the	DET
dti-1418	24	62	“	"	PUNCT
dti-1418	24	63	pill	pill	NOUN
dti-1418	24	64	-	-	PUNCT
dti-1418	24	65	in	in	ADP
dti-1418	24	66	-	-	PUNCT
dti-1418	24	67	the	the	DET
dti-1418	24	68	-	-	PUNCT
dti-1418	24	69	pocket	pocket	NOUN
dti-1418	24	70	”	"	PUNCT
dti-1418	24	71	strategy	strategy	NOUN
dti-1418	24	72	in	in	ADP
dti-1418	24	73	patients	patient	NOUN
dti-1418	24	74	with	with	ADP
dti-1418	24	75	paroxysmal	paroxysmal	ADJ
dti-1418	24	76	af.11	af.11	NOUN
dti-1418	24	77	moreover	moreover	ADV
dti-1418	24	78	,	,	PUNCT
dti-1418	24	79	in	in	ADP
dti-1418	24	80	the	the	DET
dti-1418	24	81	setting	setting	NOUN
dti-1418	24	82	of	of	ADP
dti-1418	24	83	paroxysmal	paroxysmal	ADJ
dti-1418	24	84	af	af	NOUN
dti-1418	24	85	,	,	PUNCT
dti-1418	24	86	many	many	ADJ
dti-1418	24	87	aads	aad	NOUN
dti-1418	24	88	have	have	VERB
dti-1418	24	89	a	a	DET
dti-1418	24	90	slow	slow	ADJ
dti-1418	24	91	onset	onset	NOUN
dti-1418	24	92	of	of	ADP
dti-1418	24	93	action	action	NOUN
dti-1418	24	94	(	(	PUNCT
dti-1418	24	95	ie	ie	X
dti-1418	24	96	,	,	PUNCT
dti-1418	24	97	amiodarone	amiodarone	NOUN
dti-1418	24	98	,	,	PUNCT
dti-1418	24	99	beta	beta	NOUN
dti-1418	24	100	-	-	PUNCT
dti-1418	24	101	blockers	blocker	NOUN
dti-1418	24	102	)	)	PUNCT
dti-1418	24	103	or	or	CCONJ
dti-1418	24	104	may	may	AUX
dti-1418	24	105	have	have	VERB
dti-1418	24	106	some	some	DET
dti-1418	24	107	restrictions	restriction	NOUN
dti-1418	24	108	for	for	ADP
dti-1418	24	109	use	use	NOUN
dti-1418	24	110	in	in	ADP
dti-1418	24	111	patients	patient	NOUN
dti-1418	24	112	with	with	ADP
dti-1418	24	113	underlying	underlie	VERB
dti-1418	24	114	heart	heart	NOUN
dti-1418	24	115	disease	disease	NOUN
dti-1418	24	116	(	(	PUNCT
dti-1418	24	117	class	class	NOUN
dti-1418	24	118	1	1	NUM
dti-1418	24	119	aad	aad	NOUN
dti-1418	24	120	)	)	PUNCT
dti-1418	24	121	.	.	PUNCT
dti-1418	25	1	in	in	ADP
dti-1418	25	2	view	view	NOUN
dti-1418	25	3	of	of	ADP
dti-1418	25	4	this	this	PRON
dti-1418	25	5	,	,	PUNCT
dti-1418	25	6	the	the	DET
dti-1418	25	7	development	development	NOUN
dti-1418	25	8	of	of	ADP
dti-1418	25	9	new	new	ADJ
dti-1418	25	10	and	and	CCONJ
dti-1418	25	11	effective	effective	ADJ
dti-1418	25	12	aad	aad	INTJ
dti-1418	25	13	to	to	PART
dti-1418	25	14	manage	manage	VERB
dti-1418	25	15	patients	patient	NOUN
dti-1418	25	16	with	with	ADP
dti-1418	25	17	paroxysmal	paroxysmal	ADJ
dti-1418	25	18	af	af	PROPN
dti-1418	25	19	was	be	AUX
dti-1418	25	20	sought.9,11	sought.9,11	NOUN
dti-1418	25	21	vernakalant	vernakalant	NOUN
dti-1418	25	22	was	be	AUX
dti-1418	25	23	first	first	ADV
dti-1418	25	24	used	use	VERB
dti-1418	25	25	in	in	ADP
dti-1418	25	26	clinical	clinical	ADJ
dti-1418	25	27	practice	practice	NOUN
dti-1418	25	28	in	in	ADP
dti-1418	25	29	2004	2004	NUM
dti-1418	25	30	by	by	ADP
dti-1418	25	31	craft	craft	NOUN
dti-1418	25	32	investigators,12	investigators,12	NOUN
dti-1418	25	33	under	under	ADP
dti-1418	25	34	the	the	DET
dti-1418	25	35	investigational	investigational	ADJ
dti-1418	25	36	product	product	NOUN
dti-1418	25	37	name	name	NOUN
dti-1418	25	38	of	of	ADP
dti-1418	25	39	rsd1235	rsd1235	NOUN
dti-1418	25	40	,	,	PUNCT
dti-1418	25	41	and	and	CCONJ
dti-1418	25	42	the	the	DET
dti-1418	25	43	authors	author	NOUN
dti-1418	25	44	concluded	conclude	VERB
dti-1418	25	45	that	that	SCONJ
dti-1418	25	46	rsd1235	rsd1235	NOUN
dti-1418	25	47	is	be	AUX
dti-1418	25	48	a	a	DET
dti-1418	25	49	new	new	ADJ
dti-1418	25	50	atrial	atrial	ADJ
dti-1418	25	51	-	-	PUNCT
dti-1418	25	52	selective	selective	ADJ
dti-1418	25	53	aad	aad	NOUN
dti-1418	25	54	,	,	PUNCT
dti-1418	25	55	which	which	PRON
dti-1418	25	56	is	be	AUX
dti-1418	25	57	efficacious	efficacious	ADJ
dti-1418	25	58	and	and	CCONJ
dti-1418	25	59	safe	safe	ADJ
dti-1418	25	60	for	for	ADP
dti-1418	25	61	converting	convert	VERB
dti-1418	25	62	recent	recent	ADJ
dti-1418	25	63	-	-	PUNCT
dti-1418	25	64	onset	onset	NOUN
dti-1418	25	65	af	af	NOUN
dti-1418	25	66	to	to	ADP
dti-1418	25	67	sinus	sinus	NOUN
dti-1418	25	68	rhythm	rhythm	NOUN
dti-1418	25	69	.	.	PUNCT
dti-1418	26	1	later	later	ADV
dti-1418	26	2	on	on	ADV
dti-1418	26	3	in	in	ADP
dti-1418	26	4	2007	2007	NUM
dti-1418	26	5	,	,	PUNCT
dti-1418	26	6	fedida13	fedida13	NOUN
dti-1418	26	7	reported	report	VERB
dti-1418	26	8	on	on	ADP
dti-1418	26	9	rsd1235	rsd1235	NOUN
dti-1418	26	10	using	use	VERB
dti-1418	26	11	the	the	DET
dti-1418	26	12	term	term	NOUN
dti-1418	26	13	vernakalant	vernakalant	NOUN
dti-1418	26	14	for	for	ADP
dti-1418	26	15	the	the	DET
dti-1418	26	16	first	first	ADJ
dti-1418	26	17	time	time	NOUN
dti-1418	26	18	,	,	PUNCT
dti-1418	26	19	which	which	PRON
dti-1418	26	20	was	be	AUX
dti-1418	26	21	presented	present	VERB
dti-1418	26	22	as	as	ADP
dti-1418	26	23	a	a	DET
dti-1418	26	24	novel	novel	ADJ
dti-1418	26	25	atrial	atrial	ADJ
dti-1418	26	26	-	-	PUNCT
dti-1418	26	27	selective	selective	ADJ
dti-1418	26	28	antifibrillatory	antifibrillatory	ADJ
dti-1418	26	29	agent	agent	NOUN
dti-1418	26	30	,	,	PUNCT
dti-1418	26	31	with	with	ADP
dti-1418	26	32	the	the	DET
dti-1418	26	33	electrophysiological	electrophysiological	ADJ
dti-1418	26	34	properties	property	NOUN
dti-1418	26	35	targeting	target	VERB
dti-1418	26	36	potassium	potassium	NOUN
dti-1418	26	37	channels	channel	NOUN
dti-1418	26	38	that	that	PRON
dti-1418	26	39	are	be	AUX
dti-1418	26	40	selectively	selectively	ADV
dti-1418	26	41	present	present	ADJ
dti-1418	26	42	in	in	ADP
dti-1418	26	43	human	human	ADJ
dti-1418	26	44	atria	atria	NOUN
dti-1418	26	45	;	;	PUNCT
dti-1418	26	46	also	also	ADV
dti-1418	26	47	they	they	PRON
dti-1418	26	48	reported	report	VERB
dti-1418	26	49	that	that	DET
dti-1418	26	50	vernakalant	vernakalant	NOUN
dti-1418	26	51	allows	allow	VERB
dti-1418	26	52	a	a	DET
dti-1418	26	53	safe	safe	ADJ
dti-1418	26	54	and	and	CCONJ
dti-1418	26	55	rapid	rapid	ADJ
dti-1418	26	56	conversion	conversion	NOUN
dti-1418	26	57	of	of	ADP
dti-1418	26	58	acute	acute	NOUN
dti-1418	26	59	af	af	PROPN
dti-1418	26	60	back	back	ADV
dti-1418	26	61	to	to	ADP
dti-1418	26	62	sinus	sinus	NOUN
dti-1418	26	63	rhythm	rhythm	NOUN
dti-1418	26	64	.	.	PUNCT
dti-1418	27	1	the	the	DET
dti-1418	27	2	2010	2010	NUM
dti-1418	27	3	guidelines	guideline	NOUN
dti-1418	27	4	for	for	ADP
dti-1418	27	5	the	the	DET
dti-1418	27	6	management	management	NOUN
dti-1418	27	7	of	of	ADP
dti-1418	27	8	af	af	PROPN
dti-1418	27	9	stated	state	VERB
dti-1418	27	10	that	that	DET
dti-1418	27	11	vernakalant	vernakalant	NOUN
dti-1418	27	12	has	have	AUX
dti-1418	27	13	recently	recently	ADV
dti-1418	27	14	been	be	AUX
dti-1418	27	15	recommended	recommend	VERB
dti-1418	27	16	for	for	ADP
dti-1418	27	17	approval	approval	NOUN
dti-1418	27	18	for	for	ADP
dti-1418	27	19	rapid	rapid	ADJ
dti-1418	27	20	cardioversion	cardioversion	NOUN
dti-1418	27	21	of	of	ADP
dti-1418	27	22	recent	recent	ADJ
dti-1418	27	23	-	-	PUNCT
dti-1418	27	24	onset	onset	NOUN
dti-1418	27	25	af	af	NOUN
dti-1418	27	26	to	to	ADP
dti-1418	27	27	sinus	sinus	NOUN
dti-1418	27	28	rhythm	rhythm	NOUN
dti-1418	27	29	in	in	ADP
dti-1418	27	30	adults.14	adults.14	PROPN
dti-1418	27	31	the	the	DET
dti-1418	27	32	2016	2016	NUM
dti-1418	27	33	esc	esc	NOUN
dti-1418	27	34	guidelines	guideline	NOUN
dti-1418	27	35	for	for	ADP
dti-1418	27	36	the	the	DET
dti-1418	27	37	management	management	NOUN
dti-1418	27	38	of	of	ADP
dti-1418	27	39	af	af	PROPN
dti-1418	27	40	classified	classify	VERB
dti-1418	27	41	af	af	PROPN
dti-1418	27	42	in	in	ADP
dti-1418	27	43	five	five	NUM
dti-1418	27	44	categories	category	NOUN
dti-1418	27	45	:	:	PUNCT
dti-1418	27	46	first	first	ADV
dti-1418	27	47	diagnosed	diagnose	VERB
dti-1418	27	48	,	,	PUNCT
dti-1418	27	49	paroxysmal	paroxysmal	ADJ
dti-1418	27	50	,	,	PUNCT
dti-1418	27	51	persistent	persistent	ADJ
dti-1418	27	52	,	,	PUNCT
dti-1418	27	53	long	long	ADV
dti-1418	27	54	-	-	PUNCT
dti-1418	27	55	standing	stand	VERB
dti-1418	27	56	persistent	persistent	NOUN
dti-1418	27	57	,	,	PUNCT
dti-1418	27	58	and	and	CCONJ
dti-1418	27	59	permanent	permanent	ADJ
dti-1418	27	60	;	;	PUNCT
dti-1418	27	61	also	also	ADV
dti-1418	27	62	the	the	DET
dti-1418	27	63	2016	2016	NUM
dti-1418	27	64	esc	esc	NOUN
dti-1418	27	65	guidelines	guideline	NOUN
dti-1418	27	66	stated	state	VERB
dti-1418	27	67	that	that	DET
dti-1418	27	68	vernakalant	vernakalant	NOUN
dti-1418	27	69	should	should	AUX
dti-1418	27	70	be	be	AUX
dti-1418	27	71	considered	consider	VERB
dti-1418	27	72	for	for	ADP
dti-1418	27	73	pharmacological	pharmacological	ADJ
dti-1418	27	74	cardioversion	cardioversion	NOUN
dti-1418	27	75	of	of	ADP
dti-1418	27	76	recent	recent	ADJ
dti-1418	27	77	-	-	PUNCT
dti-1418	27	78	onset	onset	NOUN
dti-1418	27	79	af	af	NOUN
dti-1418	27	80	,	,	PUNCT
dti-1418	27	81	in	in	ADP
dti-1418	27	82	patients	patient	NOUN
dti-1418	27	83	with	with	ADP
dti-1418	27	84	no	no	DET
dti-1418	27	85	history	history	NOUN
dti-1418	27	86	of	of	ADP
dti-1418	27	87	ischemic	ischemic	ADJ
dti-1418	27	88	or	or	CCONJ
dti-1418	27	89	structural	structural	ADJ
dti-1418	27	90	heart	heart	NOUN
dti-1418	27	91	disease.3	disease.3	PROPN
dti-1418	27	92	electrophysiological	electrophysiological	ADJ
dti-1418	27	93	properties	property	NOUN
dti-1418	27	94	of	of	ADP
dti-1418	27	95	vernakalant	vernakalant	NOUN
dti-1418	27	96	normal	normal	ADJ
dti-1418	27	97	atria	atria	NOUN
dti-1418	27	98	have	have	VERB
dti-1418	27	99	a	a	DET
dti-1418	27	100	resting	rest	VERB
dti-1418	27	101	membrane	membrane	NOUN
dti-1418	27	102	potential	potential	NOUN
dti-1418	27	103	of	of	ADP
dti-1418	27	104	(	(	PUNCT
dti-1418	27	105	–	–	PUNCT
dti-1418	27	106	70	70	NUM
dti-1418	27	107	)	)	PUNCT
dti-1418	27	108	to	to	ADP
dti-1418	27	109	(	(	PUNCT
dti-1418	27	110	–	–	PUNCT
dti-1418	27	111	80	80	NUM
dti-1418	27	112	)	)	PUNCT
dti-1418	27	113	mv	mv	NOUN
dti-1418	27	114	,	,	PUNCT
dti-1418	27	115	about	about	ADV
dti-1418	27	116	10	10	NUM
dti-1418	27	117	mv	mv	NUM
dti-1418	27	118	more	more	ADV
dti-1418	27	119	positive	positive	ADJ
dti-1418	27	120	than	than	ADP
dti-1418	27	121	that	that	PRON
dti-1418	27	122	of	of	ADP
dti-1418	27	123	the	the	DET
dti-1418	27	124	ventricles	ventricle	NOUN
dti-1418	27	125	.	.	PUNCT
dti-1418	28	1	during	during	ADP
dti-1418	28	2	af	af	PROPN
dti-1418	28	3	,	,	PUNCT
dti-1418	28	4	atria	atria	PROPN
dti-1418	28	5	fail	fail	VERB
dti-1418	28	6	to	to	PART
dti-1418	28	7	fully	fully	ADV
dti-1418	28	8	repolarize	repolarize	VERB
dti-1418	28	9	,	,	PUNCT
dti-1418	28	10	and	and	CCONJ
dti-1418	28	11	therefore	therefore	ADV
dti-1418	28	12	,	,	PUNCT
dti-1418	28	13	the	the	DET
dti-1418	28	14	difference	difference	NOUN
dti-1418	28	15	in	in	ADP
dti-1418	28	16	resting	rest	VERB
dti-1418	28	17	membrane	membrane	NOUN
dti-1418	28	18	between	between	ADP
dti-1418	28	19	atria	atria	NOUN
dti-1418	28	20	and	and	CCONJ
dti-1418	28	21	ventricles	ventricle	NOUN
dti-1418	28	22	increases	increase	NOUN
dti-1418	28	23	,	,	PUNCT
dti-1418	28	24	and	and	CCONJ
dti-1418	28	25	this	this	DET
dti-1418	28	26	accentuated	accentuate	VERB
dti-1418	28	27	difference	difference	NOUN
dti-1418	28	28	is	be	AUX
dti-1418	28	29	thought	think	VERB
dti-1418	28	30	to	to	PART
dti-1418	28	31	play	play	VERB
dti-1418	28	32	a	a	DET
dti-1418	28	33	part	part	NOUN
dti-1418	28	34	in	in	ADP
dti-1418	28	35	vernakalant	vernakalant	NOUN
dti-1418	28	36	selectivity	selectivity	NOUN
dti-1418	28	37	to	to	ADP
dti-1418	28	38	atria	atria	PROPN
dti-1418	28	39	as	as	SCONJ
dti-1418	28	40	opposed	oppose	VERB
dti-1418	28	41	to	to	ADP
dti-1418	28	42	normal	normal	ADJ
dti-1418	28	43	ventricles.15	ventricles.15	NOUN
dti-1418	28	44	vernakalant	vernakalant	NOUN
dti-1418	28	45	is	be	AUX
dti-1418	28	46	a	a	DET
dti-1418	28	47	relatively	relatively	ADV
dti-1418	28	48	new	new	ADJ
dti-1418	28	49	aad	aad	NOUN
dti-1418	28	50	,	,	PUNCT
dti-1418	28	51	and	and	CCONJ
dti-1418	28	52	its	its	PRON
dti-1418	28	53	antiarrhythmic	antiarrhythmic	ADJ
dti-1418	28	54	activity	activity	NOUN
dti-1418	28	55	is	be	AUX
dti-1418	28	56	mainly	mainly	ADV
dti-1418	28	57	correlated	correlate	VERB
dti-1418	28	58	to	to	ADP
dti-1418	28	59	the	the	DET
dti-1418	28	60	blocking	block	VERB
dti-1418	28	61	property	property	NOUN
dti-1418	28	62	of	of	ADP
dti-1418	28	63	the	the	DET
dti-1418	28	64	sodium	sodium	NOUN
dti-1418	28	65	channels	channel	NOUN
dti-1418	28	66	(	(	PUNCT
dti-1418	28	67	ina).15	ina).15	VERB
dti-1418	28	68	moreover	moreover	ADV
dti-1418	28	69	,	,	PUNCT
dti-1418	28	70	vernakalant	vernakalant	NOUN
dti-1418	28	71	action	action	NOUN
dti-1418	28	72	varies	vary	VERB
dti-1418	28	73	with	with	ADP
dti-1418	28	74	heart	heart	NOUN
dti-1418	28	75	rate	rate	NOUN
dti-1418	28	76	and	and	CCONJ
dti-1418	28	77	with	with	ADP
dti-1418	28	78	baseline	baseline	ADJ
dti-1418	28	79	membrane	membrane	NOUN
dti-1418	28	80	potential	potential	NOUN
dti-1418	28	81	;	;	PUNCT
dti-1418	28	82	at	at	ADP
dti-1418	28	83	low	low	ADJ
dti-1418	28	84	rates	rate	NOUN
dti-1418	28	85	and	and	CCONJ
dti-1418	28	86	at	at	ADP
dti-1418	28	87	negative	negative	ADJ
dti-1418	28	88	membrane	membrane	NOUN
dti-1418	28	89	potential	potential	NOUN
dti-1418	28	90	,	,	PUNCT
dti-1418	28	91	vernakalant	vernakalant	NOUN
dti-1418	28	92	has	have	VERB
dti-1418	28	93	a	a	DET
dti-1418	28	94	relatively	relatively	ADV
dti-1418	28	95	weak	weak	ADJ
dti-1418	28	96	blocking	block	VERB
dti-1418	28	97	activity	activity	NOUN
dti-1418	28	98	of	of	ADP
dti-1418	28	99	the	the	DET
dti-1418	28	100	ina.13	ina.13	NOUN
dti-1418	28	101	as	as	ADP
dti-1418	28	102	the	the	DET
dti-1418	28	103	heart	heart	NOUN
dti-1418	28	104	rate	rate	NOUN
dti-1418	28	105	increases	increase	NOUN
dti-1418	28	106	,	,	PUNCT
dti-1418	28	107	the	the	DET
dti-1418	28	108	affinity	affinity	NOUN
dti-1418	28	109	of	of	ADP
dti-1418	28	110	vernakalant	vernakalant	NOUN
dti-1418	28	111	for	for	ADP
dti-1418	28	112	ina	ina	PROPN
dti-1418	28	113	increases	increase	NOUN
dti-1418	28	114	and	and	CCONJ
dti-1418	28	115	leads	lead	VERB
dti-1418	28	116	to	to	ADP
dti-1418	28	117	greater	great	ADJ
dti-1418	28	118	ina	ina	NOUN
dti-1418	28	119	blockade	blockade	NOUN
dti-1418	28	120	and	and	CCONJ
dti-1418	28	121	fast	fast	ADJ
dti-1418	28	122	onset	onset	NOUN
dti-1418	28	123	of	of	ADP
dti-1418	28	124	action	action	NOUN
dti-1418	28	125	,	,	PUNCT
dti-1418	28	126	and	and	CCONJ
dti-1418	28	127	this	this	DET
dti-1418	28	128	phenomenon	phenomenon	NOUN
dti-1418	28	129	explains	explain	VERB
dti-1418	28	130	why	why	SCONJ
dti-1418	28	131	vernakalant	vernakalant	NOUN
dti-1418	28	132	is	be	AUX
dti-1418	28	133	not	not	PART
dti-1418	28	134	efficient	efficient	ADJ
dti-1418	28	135	as	as	ADP
dti-1418	28	136	preventive	preventive	ADJ
dti-1418	28	137	therapy.15,16	therapy.15,16	NOUN
dti-1418	28	138	interestingly	interestingly	ADV
dti-1418	28	139	,	,	PUNCT
dti-1418	28	140	vernakalant	vernakalant	NOUN
dti-1418	28	141	demonstrates	demonstrate	VERB
dti-1418	28	142	a	a	DET
dti-1418	28	143	quick	quick	ADJ
dti-1418	28	144	offset	offset	NOUN
dti-1418	28	145	of	of	ADP
dti-1418	28	146	binding	bind	VERB
dti-1418	28	147	once	once	SCONJ
dti-1418	28	148	heart	heart	NOUN
dti-1418	28	149	rate	rate	NOUN
dti-1418	28	150	slows	slow	VERB
dti-1418	28	151	and	and	CCONJ
dti-1418	28	152	when	when	SCONJ
dti-1418	28	153	ina	ina	PROPN
dti-1418	28	154	blockade	blockade	VERB
dti-1418	28	155	in	in	ADP
dti-1418	28	156	no	no	ADV
dti-1418	28	157	longer	long	ADV
dti-1418	28	158	required.15	required.15	NOUN
dti-1418	28	159	moreover	moreover	ADV
dti-1418	28	160	,	,	PUNCT
dti-1418	28	161	vernakalant	vernakalant	NOUN
dti-1418	28	162	is	be	AUX
dti-1418	28	163	able	able	ADJ
dti-1418	28	164	to	to	PART
dti-1418	28	165	block	block	VERB
dti-1418	28	166	certain	certain	ADJ
dti-1418	28	167	potassium	potassium	NOUN
dti-1418	28	168	channels	channel	NOUN
dti-1418	28	169	,	,	PUNCT
dti-1418	28	170	ikur	ikur	NOUN
dti-1418	28	171	(	(	PUNCT
dti-1418	28	172	atrial	atrial	ADJ
dti-1418	28	173	-	-	PUNCT
dti-1418	28	174	selective	selective	ADJ
dti-1418	28	175	potassium	potassium	NOUN
dti-1418	28	176	channels	channel	NOUN
dti-1418	28	177	)	)	PUNCT
dti-1418	28	178	,	,	PUNCT
dti-1418	28	179	involved	involve	VERB
dti-1418	28	180	in	in	ADP
dti-1418	28	181	atrial	atrial	ADJ
dti-1418	28	182	repolarization	repolarization	NOUN
dti-1418	28	183	along	along	ADP
dti-1418	28	184	with	with	ADP
dti-1418	28	185	other	other	ADJ
dti-1418	28	186	potassium	potassium	NOUN
dti-1418	28	187	channels	channel	NOUN
dti-1418	28	188	(	(	PUNCT
dti-1418	28	189	ikach	ikach	PROPN
dti-1418	28	190	)	)	PUNCT
dti-1418	28	191	,	,	PUNCT
dti-1418	28	192	resulting	result	VERB
dti-1418	28	193	in	in	ADP
dti-1418	28	194	prolonged	prolonged	ADJ
dti-1418	28	195	action	action	NOUN
dti-1418	28	196	potential	potential	ADJ
dti-1418	28	197	plateau	plateau	NOUN
dti-1418	28	198	;	;	PUNCT
dti-1418	28	199	similarly	similarly	ADV
dti-1418	28	200	,	,	PUNCT
dti-1418	28	201	vernakalant	vernakalant	NOUN
dti-1418	28	202	blocks	block	NOUN
dti-1418	28	203	potassium	potassium	NOUN
dti-1418	28	204	channels	channel	NOUN
dti-1418	28	205	ito	ito	PROPN
dti-1418	28	206	,	,	PUNCT
dti-1418	28	207	involved	involve	VERB
dti-1418	28	208	more	more	ADV
dti-1418	28	209	with	with	ADP
dti-1418	28	210	atrial	atrial	ADJ
dti-1418	28	211	than	than	ADP
dti-1418	28	212	ventricular	ventricular	ADJ
dti-1418	28	213	refractoriness.13,17	refractoriness.13,17	NOUN
dti-1418	28	214	herg	herg	PROPN
dti-1418	28	215	is	be	AUX
dti-1418	28	216	a	a	DET
dti-1418	28	217	gene	gene	NOUN
dti-1418	28	218	that	that	PRON
dti-1418	28	219	codes	code	VERB
dti-1418	28	220	for	for	ADP
dti-1418	28	221	potassium	potassium	NOUN
dti-1418	28	222	channel	channel	NOUN
dti-1418	28	223	known	know	VERB
dti-1418	28	224	for	for	ADP
dti-1418	28	225	its	its	PRON
dti-1418	28	226	contribution	contribution	NOUN
dti-1418	28	227	to	to	ADP
dti-1418	28	228	repolarization	repolarization	NOUN
dti-1418	28	229	through	through	ADP
dti-1418	28	230	ikr	ikr	PROPN
dti-1418	28	231	(	(	PUNCT
dti-1418	28	232	“	"	PUNCT
dti-1418	28	233	rapid	rapid	ADJ
dti-1418	28	234	”	"	PUNCT
dti-1418	28	235	delayed	delay	VERB
dti-1418	28	236	rectifier	rectifier	NOUN
dti-1418	28	237	current	current	NOUN
dti-1418	28	238	)	)	PUNCT
dti-1418	28	239	.	.	PUNCT
dti-1418	29	1	when	when	SCONJ
dti-1418	29	2	this	this	DET
dti-1418	29	3	channel	channel	NOUN
dti-1418	29	4	is	be	AUX
dti-1418	29	5	inhibited	inhibit	VERB
dti-1418	29	6	or	or	CCONJ
dti-1418	29	7	compromised	compromise	VERB
dti-1418	29	8	,	,	PUNCT
dti-1418	29	9	it	it	PRON
dti-1418	29	10	can	can	AUX
dti-1418	29	11	result	result	VERB
dti-1418	29	12	in	in	ADP
dti-1418	29	13	a	a	DET
dti-1418	29	14	long	long	ADJ
dti-1418	29	15	qt	qt	NOUN
dti-1418	29	16	interval.17	interval.17	PROPN
dti-1418	29	17	vernakalant	vernakalant	NOUN
dti-1418	29	18	is	be	AUX
dti-1418	29	19	known	know	VERB
dti-1418	29	20	to	to	PART
dti-1418	29	21	partially	partially	ADV
dti-1418	29	22	blocks	block	VERB
dti-1418	29	23	the	the	DET
dti-1418	29	24	herg	herg	PROPN
dti-1418	29	25	channel	channel	NOUN
dti-1418	29	26	(	(	PUNCT
dti-1418	29	27	underlying	underlying	ADJ
dti-1418	29	28	channel	channel	NOUN
dti-1418	29	29	of	of	ADP
dti-1418	29	30	ikr	ikr	PROPN
dti-1418	29	31	)	)	PUNCT
dti-1418	29	32	;	;	PUNCT
dti-1418	29	33	this	this	PRON
dti-1418	29	34	may	may	AUX
dti-1418	29	35	prolong	prolong	VERB
dti-1418	29	36	qt	qt	NOUN
dti-1418	29	37	interval	interval	NOUN
dti-1418	29	38	;	;	PUNCT
dti-1418	29	39	however	however	ADV
dti-1418	29	40	,	,	PUNCT
dti-1418	29	41	this	this	DET
dti-1418	29	42	blockade	blockade	NOUN
dti-1418	29	43	occurs	occur	VERB
dti-1418	29	44	at	at	ADP
dti-1418	29	45	minimal	minimal	ADJ
dti-1418	29	46	level	level	NOUN
dti-1418	29	47	and	and	CCONJ
dti-1418	29	48	usually	usually	ADV
dti-1418	29	49	has	have	VERB
dti-1418	29	50	no	no	DET
dti-1418	29	51	conclusive	conclusive	ADJ
dti-1418	29	52	clinical	clinical	ADJ
dti-1418	29	53	effect	effect	NOUN
dti-1418	29	54	at	at	ADP
dti-1418	29	55	target	target	NOUN
dti-1418	29	56	vernakalant	vernakalant	NOUN
dti-1418	29	57	concentrations.15	concentrations.15	NOUN
dti-1418	29	58	all	all	DET
dti-1418	29	59	these	these	DET
dti-1418	29	60	properties	property	NOUN
dti-1418	29	61	result	result	VERB
dti-1418	29	62	in	in	ADP
dti-1418	29	63	clinical	clinical	ADJ
dti-1418	29	64	and	and	CCONJ
dti-1418	29	65	electrophysiological	electrophysiological	ADJ
dti-1418	29	66	effects	effect	NOUN
dti-1418	29	67	of	of	ADP
dti-1418	29	68	vernakalant	vernakalant	NOUN
dti-1418	29	69	,	,	PUNCT
dti-1418	29	70	with	with	ADP
dti-1418	29	71	prolongation	prolongation	NOUN
dti-1418	29	72	of	of	ADP
dti-1418	29	73	atrial	atrial	ADJ
dti-1418	29	74	refractory	refractory	NOUN
dti-1418	29	75	period	period	NOUN
dti-1418	29	76	,	,	PUNCT
dti-1418	29	77	slowing	slow	VERB
dti-1418	29	78	atrio	atrio	NOUN
dti-1418	29	79	-	-	PUNCT
dti-1418	29	80	ventricular	ventricular	ADJ
dti-1418	29	81	(	(	PUNCT
dti-1418	29	82	av	av	NOUN
dti-1418	29	83	)	)	PUNCT
dti-1418	29	84	nodal	nodal	ADJ
dti-1418	29	85	conduction	conduction	NOUN
dti-1418	29	86	,	,	PUNCT
dti-1418	29	87	but	but	CCONJ
dti-1418	29	88	without	without	ADP
dti-1418	29	89	effect	effect	NOUN
dti-1418	29	90	on	on	ADP
dti-1418	29	91	av	av	PROPN
dti-1418	29	92	nodal	nodal	NOUN
dti-1418	29	93	refractoriness	refractoriness	NOUN
dti-1418	29	94	or	or	CCONJ
dti-1418	29	95	on	on	ADP
dti-1418	29	96	ventricular	ventricular	ADJ
dti-1418	29	97	cells;18	cells;18	PROPN
dti-1418	29	98	moreover	moreover	ADV
dti-1418	29	99	,	,	PUNCT
dti-1418	29	100	qt	qt	NOUN
dti-1418	29	101	interval	interval	NOUN
dti-1418	29	102	and	and	CCONJ
dti-1418	29	103	ventricular	ventricular	ADJ
dti-1418	29	104	effective	effective	ADJ
dti-1418	29	105	refractory	refractory	NOUN
dti-1418	29	106	period	period	NOUN
dti-1418	29	107	do	do	AUX
dti-1418	29	108	not	not	PART
dti-1418	29	109	significantly	significantly	ADV
dti-1418	29	110	change	change	VERB
dti-1418	29	111	at	at	ADP
dti-1418	29	112	target	target	NOUN
dti-1418	29	113	dosage	dosage	NOUN
dti-1418	29	114	.	.	PUNCT
dti-1418	30	1	pharmacokinetics	pharmacokinetic	NOUN
dti-1418	30	2	of	of	ADP
dti-1418	30	3	vernakalant	vernakalant	NOUN
dti-1418	30	4	when	when	SCONJ
dti-1418	30	5	vernakalant	vernakalant	NOUN
dti-1418	30	6	hydrochloride	hydrochloride	NOUN
dti-1418	30	7	is	be	AUX
dti-1418	30	8	infused	infuse	VERB
dti-1418	30	9	at	at	ADP
dti-1418	30	10	a	a	DET
dti-1418	30	11	dose	dose	NOUN
dti-1418	30	12	of	of	ADP
dti-1418	30	13	0.1	0.1	NUM
dti-1418	30	14	to	to	PART
dti-1418	30	15	5	5	NUM
dti-1418	30	16	mg	mg	PROPN
dti-1418	30	17	/	/	SYM
dti-1418	30	18	kg	kg	PROPN
dti-1418	30	19	,	,	PUNCT
dti-1418	30	20	intravenously	intravenously	ADV
dti-1418	30	21	over	over	ADP
dti-1418	30	22	10	10	NUM
dti-1418	30	23	min	min	NOUN
dti-1418	30	24	,	,	PUNCT
dti-1418	30	25	the	the	DET
dti-1418	30	26	maximum	maximum	ADJ
dti-1418	30	27	plasma	plasma	NOUN
dti-1418	30	28	concentration	concentration	NOUN
dti-1418	30	29	(	(	PUNCT
dti-1418	30	30	cmax	cmax	NOUN
dti-1418	30	31	)	)	PUNCT
dti-1418	30	32	reaches	reach	VERB
dti-1418	30	33	0.08	0.08	NUM
dti-1418	30	34	to	to	PART
dti-1418	30	35	4	4	NUM
dti-1418	30	36	µg	µg	ADV
dti-1418	30	37	/	/	SYM
dti-1418	30	38	ml	ml	NOUN
dti-1418	30	39	and	and	CCONJ
dti-1418	30	40	increases	increase	VERB
dti-1418	30	41	linearly	linearly	ADV
dti-1418	30	42	with	with	ADP
dti-1418	30	43	dose	dose	NOUN
dti-1418	30	44	,	,	PUNCT
dti-1418	30	45	the	the	DET
dti-1418	30	46	average	average	ADJ
dti-1418	30	47	cmax	cmax	NOUN
dti-1418	30	48	reaches	reach	VERB
dti-1418	30	49	3.9	3.9	NUM
dti-1418	30	50	μg	μg	NOUN
dti-1418	30	51	/	/	SYM
dti-1418	30	52	ml	ml	NOUN
dti-1418	30	53	after	after	ADP
dti-1418	30	54	a	a	DET
dti-1418	30	55	single	single	ADJ
dti-1418	30	56	10	10	NUM
dti-1418	30	57	-	-	PUNCT
dti-1418	30	58	min	min	NOUN
dti-1418	30	59	infusion	infusion	NOUN
dti-1418	30	60	of	of	ADP
dti-1418	30	61	3	3	NUM
dti-1418	30	62	mg	mg	PROPN
dti-1418	30	63	/	/	SYM
dti-1418	30	64	kg	kg	PROPN
dti-1418	30	65	,	,	PUNCT
dti-1418	30	66	and	and	CCONJ
dti-1418	30	67	the	the	DET
dti-1418	30	68	average	average	ADJ
dti-1418	30	69	cmax	cmax	NOUN
dti-1418	30	70	is	be	AUX
dti-1418	30	71	4.3	4.3	NUM
dti-1418	30	72	μg	μg	NOUN
dti-1418	30	73	/	/	SYM
dti-1418	30	74	ml	ml	NOUN
dti-1418	30	75	after	after	ADP
dti-1418	30	76	15	15	NUM
dti-1418	30	77	min	min	NOUN
dti-1418	30	78	of	of	ADP
dti-1418	30	79	a	a	DET
dti-1418	30	80	second	second	ADJ
dti-1418	30	81	infusion	infusion	NOUN
dti-1418	30	82	of	of	ADP
dti-1418	30	83	2	2	NUM
dti-1418	30	84	mg	mg	PROPN
dti-1418	30	85	/	/	SYM
dti-1418	30	86	kg.19	kg.19	NOUN
dti-1418	30	87	moreover	moreover	ADV
dti-1418	30	88	,	,	PUNCT
dti-1418	30	89	the	the	DET
dti-1418	30	90	dose	dose	NOUN
dti-1418	30	91	-	-	PUNCT
dti-1418	30	92	normalized	normalize	VERB
dti-1418	30	93	values	value	NOUN
dti-1418	30	94	for	for	ADP
dti-1418	30	95	the	the	DET
dti-1418	30	96	area	area	NOUN
dti-1418	30	97	under	under	ADP
dti-1418	30	98	the	the	DET
dti-1418	30	99	concentration	concentration	NOUN
dti-1418	30	100	-	-	PUNCT
dti-1418	30	101	time	time	NOUN
dti-1418	30	102	curve	curve	NOUN
dti-1418	30	103	(	(	PUNCT
dti-1418	30	104	auc	auc	NOUN
dti-1418	30	105	)	)	PUNCT
dti-1418	30	106	do	do	AUX
dti-1418	30	107	not	not	PART
dti-1418	30	108	differ	differ	VERB
dti-1418	30	109	significantly	significantly	ADV
dti-1418	30	110	among	among	ADP
dti-1418	30	111	doses	dose	NOUN
dti-1418	30	112	,	,	PUNCT
dti-1418	30	113	although	although	SCONJ
dti-1418	30	114	the	the	DET
dti-1418	30	115	cmax	cmax	NOUN
dti-1418	30	116	is	be	AUX
dti-1418	30	117	dose	dose	VERB
dti-1418	30	118	proportional	proportional	ADJ
dti-1418	30	119	.	.	PUNCT
dti-1418	31	1	vernakalant	vernakalant	NOUN
dti-1418	31	2	half	half	ADJ
dti-1418	31	3	-	-	PUNCT
dti-1418	31	4	life	life	NOUN
dti-1418	31	5	(	(	PUNCT
dti-1418	31	6	t½	t½	NOUN
dti-1418	31	7	)	)	PUNCT
dti-1418	31	8	is	be	AUX
dti-1418	31	9	between	between	ADP
dti-1418	31	10	2	2	NUM
dti-1418	31	11	and	and	CCONJ
dti-1418	31	12	4	4	NUM
dti-1418	31	13	h	h	NOUN
dti-1418	31	14	according	accord	VERB
dti-1418	31	15	to	to	ADP
dti-1418	31	16	cytochrome	cytochrome	ADJ
dti-1418	31	17	p450	p450	PROPN
dti-1418	31	18	enzyme	enzyme	NOUN
dti-1418	31	19	metabolizing	metabolize	VERB
dti-1418	31	20	activity.19	activity.19	NOUN
dti-1418	31	21	of	of	ADP
dti-1418	31	22	note	note	NOUN
dti-1418	31	23	,	,	PUNCT
dti-1418	31	24	the	the	DET
dti-1418	31	25	auc	auc	NOUN
dti-1418	31	26	between	between	ADP
dti-1418	31	27	0	0	NUM
dti-1418	31	28	and	and	CCONJ
dti-1418	31	29	90	90	NUM
dti-1418	31	30	min	min	NOUN
dti-1418	31	31	after	after	ADP
dti-1418	31	32	infusion	infusion	NOUN
dti-1418	31	33	of	of	ADP
dti-1418	31	34	vernakalant	vernakalant	NOUN
dti-1418	31	35	is	be	AUX
dti-1418	31	36	estimated	estimate	VERB
dti-1418	31	37	to	to	PART
dti-1418	31	38	be	be	AUX
dti-1418	31	39	15	15	NUM
dti-1418	31	40	%	%	NOUN
dti-1418	31	41	higher	high	ADJ
dti-1418	31	42	in	in	ADP
dti-1418	31	43	cyp2d6	cyp2d6	NOUN
dti-1418	31	44	poor	poor	ADJ
dti-1418	31	45	metabolizers	metabolizer	NOUN
dti-1418	31	46	than	than	ADP
dti-1418	31	47	extensive	extensive	ADJ
dti-1418	31	48	metabolizers	metabolizer	NOUN
dti-1418	31	49	,	,	PUNCT
dti-1418	31	50	with	with	SCONJ
dti-1418	31	51	age	age	NOUN
dti-1418	31	52	and	and	CCONJ
dti-1418	31	53	serum	serum	NOUN
dti-1418	31	54	kossaify	kossaify	VERB
dti-1418	31	55	3	3	NUM
dti-1418	31	56	creatinine	creatinine	NOUN
dti-1418	31	57	having	have	VERB
dti-1418	31	58	smaller	small	ADJ
dti-1418	31	59	influences	influence	NOUN
dti-1418	31	60	on	on	ADP
dti-1418	31	61	exposure	exposure	NOUN
dti-1418	31	62	;	;	PUNCT
dti-1418	31	63	therefore	therefore	ADV
dti-1418	31	64	,	,	PUNCT
dti-1418	31	65	dose	dose	NOUN
dti-1418	31	66	adjustments	adjustment	NOUN
dti-1418	31	67	based	base	VERB
dti-1418	31	68	on	on	ADP
dti-1418	31	69	patient	patient	ADJ
dti-1418	31	70	characteristics	characteristic	NOUN
dti-1418	31	71	(	(	PUNCT
dti-1418	31	72	concomitant	concomitant	ADJ
dti-1418	31	73	drugs	drug	NOUN
dti-1418	31	74	,	,	PUNCT
dti-1418	31	75	renal	renal	ADJ
dti-1418	31	76	function	function	NOUN
dti-1418	31	77	,	,	PUNCT
dti-1418	31	78	age	age	NOUN
dti-1418	31	79	,	,	PUNCT
dti-1418	31	80	etc	etc	X
dti-1418	31	81	)	)	PUNCT
dti-1418	31	82	are	be	AUX
dti-1418	31	83	unnecessary	unnecessary	ADJ
dti-1418	31	84	for	for	ADP
dti-1418	31	85	intravenous	intravenous	ADJ
dti-1418	31	86	vernakalant.20,21	vernakalant.20,21	NOUN
dti-1418	31	87	in	in	ADP
dti-1418	31	88	this	this	DET
dti-1418	31	89	regard	regard	NOUN
dti-1418	31	90	,	,	PUNCT
dti-1418	31	91	there	there	PRON
dti-1418	31	92	is	be	VERB
dti-1418	31	93	no	no	DET
dti-1418	31	94	dosage	dosage	NOUN
dti-1418	31	95	adjustment	adjustment	NOUN
dti-1418	31	96	required	require	VERB
dti-1418	31	97	in	in	ADP
dti-1418	31	98	patient	patient	NOUN
dti-1418	31	99	with	with	ADP
dti-1418	31	100	renal	renal	ADJ
dti-1418	31	101	or	or	CCONJ
dti-1418	31	102	hepatic	hepatic	ADJ
dti-1418	31	103	failure	failure	NOUN
dti-1418	31	104	,	,	PUNCT
dti-1418	31	105	or	or	CCONJ
dti-1418	31	106	in	in	ADP
dti-1418	31	107	the	the	DET
dti-1418	31	108	elderly	elderly	ADJ
dti-1418	31	109	;	;	PUNCT
dti-1418	31	110	however	however	ADV
dti-1418	31	111	,	,	PUNCT
dti-1418	31	112	there	there	PRON
dti-1418	31	113	is	be	VERB
dti-1418	31	114	currently	currently	ADV
dti-1418	31	115	not	not	PART
dti-1418	31	116	enough	enough	ADJ
dti-1418	31	117	data	datum	NOUN
dti-1418	31	118	to	to	PART
dti-1418	31	119	recommend	recommend	VERB
dti-1418	31	120	use	use	NOUN
dti-1418	31	121	of	of	ADP
dti-1418	31	122	vernakalant	vernakalant	NOUN
dti-1418	31	123	in	in	ADP
dti-1418	31	124	patients	patient	NOUN
dti-1418	31	125	below	below	ADP
dti-1418	31	126	18	18	NUM
dti-1418	31	127	years	year	NOUN
dti-1418	31	128	old.21	old.21	PROPN
dti-1418	31	129	the	the	DET
dti-1418	31	130	drug	drug	NOUN
dti-1418	31	131	is	be	AUX
dti-1418	31	132	extensively	extensively	ADV
dti-1418	31	133	and	and	CCONJ
dti-1418	31	134	rapidly	rapidly	ADV
dti-1418	31	135	distributed	distribute	VERB
dti-1418	31	136	in	in	ADP
dti-1418	31	137	the	the	DET
dti-1418	31	138	body	body	NOUN
dti-1418	31	139	after	after	ADP
dti-1418	31	140	intravenous	intravenous	ADJ
dti-1418	31	141	infusion	infusion	NOUN
dti-1418	31	142	,	,	PUNCT
dti-1418	31	143	with	with	ADP
dti-1418	31	144	a	a	DET
dti-1418	31	145	serum	serum	NOUN
dti-1418	31	146	free	free	ADJ
dti-1418	31	147	fraction	fraction	NOUN
dti-1418	31	148	of	of	ADP
dti-1418	31	149	53	53	NUM
dti-1418	31	150	%	%	NOUN
dti-1418	31	151	to	to	PART
dti-1418	31	152	63	63	NUM
dti-1418	31	153	%	%	NOUN
dti-1418	31	154	at	at	ADP
dti-1418	31	155	concentration	concentration	NOUN
dti-1418	31	156	range	range	NOUN
dti-1418	31	157	of	of	ADP
dti-1418	31	158	1	1	NUM
dti-1418	31	159	to	to	PART
dti-1418	31	160	5	5	NUM
dti-1418	31	161	μg	μg	PROPN
dti-1418	31	162	/	/	SYM
dti-1418	31	163	ml.20	ml.20	PROPN
dti-1418	31	164	vernakalant	vernakalant	NOUN
dti-1418	31	165	is	be	AUX
dti-1418	31	166	not	not	PART
dti-1418	31	167	highly	highly	ADV
dti-1418	31	168	protein	protein	NOUN
dti-1418	31	169	bound	bind	VERB
dti-1418	31	170	and	and	CCONJ
dti-1418	31	171	accordingly	accordingly	ADV
dti-1418	31	172	,	,	PUNCT
dti-1418	31	173	there	there	PRON
dti-1418	31	174	is	be	VERB
dti-1418	31	175	no	no	DET
dti-1418	31	176	significant	significant	ADJ
dti-1418	31	177	competition	competition	NOUN
dti-1418	31	178	between	between	ADP
dti-1418	31	179	vernakalant	vernakalant	NOUN
dti-1418	31	180	and	and	CCONJ
dti-1418	31	181	other	other	ADJ
dti-1418	31	182	highly	highly	ADV
dti-1418	31	183	protein	protein	NOUN
dti-1418	31	184	-	-	PUNCT
dti-1418	31	185	bound	bind	VERB
dti-1418	31	186	drugs	drug	NOUN
dti-1418	31	187	such	such	ADJ
dti-1418	31	188	as	as	ADP
dti-1418	31	189	amiodarone	amiodarone	NOUN
dti-1418	31	190	,	,	PUNCT
dti-1418	31	191	warfarin	warfarin	NOUN
dti-1418	31	192	,	,	PUNCT
dti-1418	31	193	propranolol	propranolol	NOUN
dti-1418	31	194	,	,	PUNCT
dti-1418	31	195	diltiazem	diltiazem	NOUN
dti-1418	31	196	,	,	PUNCT
dti-1418	31	197	and	and	CCONJ
dti-1418	31	198	verapamil.21,22	verapamil.21,22	NOUN
dti-1418	31	199	clinical	clinical	ADJ
dti-1418	31	200	use	use	NOUN
dti-1418	31	201	of	of	ADP
dti-1418	31	202	vernakalant	vernakalant	NOUN
dti-1418	31	203	since	since	SCONJ
dti-1418	31	204	2004	2004	NUM
dti-1418	31	205	,	,	PUNCT
dti-1418	31	206	vernakalant	vernakalant	NOUN
dti-1418	31	207	(	(	PUNCT
dti-1418	31	208	rsd1235	rsd1235	PROPN
dti-1418	31	209	)	)	PUNCT
dti-1418	31	210	was	be	AUX
dti-1418	31	211	presented	present	VERB
dti-1418	31	212	by	by	ADP
dti-1418	31	213	the	the	DET
dti-1418	31	214	craft	craft	NOUN
dti-1418	31	215	investigators	investigator	NOUN
dti-1418	31	216	as	as	ADP
dti-1418	31	217	a	a	DET
dti-1418	31	218	new	new	ADJ
dti-1418	31	219	atrial	atrial	ADJ
dti-1418	31	220	-	-	PUNCT
dti-1418	31	221	selective	selective	ADJ
dti-1418	31	222	aad	aad	NOUN
dti-1418	31	223	,	,	PUNCT
dti-1418	31	224	efficacious	efficacious	ADJ
dti-1418	31	225	and	and	CCONJ
dti-1418	31	226	safe	safe	ADJ
dti-1418	31	227	for	for	ADP
dti-1418	31	228	converting	convert	VERB
dti-1418	31	229	recent	recent	ADJ
dti-1418	31	230	-	-	PUNCT
dti-1418	31	231	onset	onset	ADJ
dti-1418	31	232	af	af	NOUN
dti-1418	31	233	to	to	ADP
dti-1418	31	234	sinus	sinus	NOUN
dti-1418	31	235	rhythm.12	rhythm.12	NOUN
dti-1418	31	236	later	later	ADV
dti-1418	31	237	on	on	ADV
dti-1418	31	238	,	,	PUNCT
dti-1418	31	239	vernakalant	vernakalant	NOUN
dti-1418	31	240	has	have	AUX
dti-1418	31	241	been	be	AUX
dti-1418	31	242	tested	test	VERB
dti-1418	31	243	in	in	ADP
dti-1418	31	244	three	three	NUM
dti-1418	31	245	placebo	placebo	NOUN
dti-1418	31	246	controlled	control	VERB
dti-1418	31	247	trials	trial	NOUN
dti-1418	31	248	(	(	PUNCT
dti-1418	31	249	act	act	VERB
dti-1418	31	250	i	i	PRON
dti-1418	31	251	,	,	PUNCT
dti-1418	31	252	act	act	PROPN
dti-1418	31	253	ii	ii	PROPN
dti-1418	31	254	,	,	PUNCT
dti-1418	31	255	and	and	CCONJ
dti-1418	31	256	act	act	PROPN
dti-1418	31	257	iii	iii	NUM
dti-1418	31	258	)	)	PUNCT
dti-1418	31	259	and	and	CCONJ
dti-1418	31	260	was	be	AUX
dti-1418	31	261	more	more	ADV
dti-1418	31	262	effective	effective	ADJ
dti-1418	31	263	than	than	ADP
dti-1418	31	264	placebo	placebo	NOUN
dti-1418	31	265	for	for	ADP
dti-1418	31	266	the	the	DET
dti-1418	31	267	rapid	rapid	ADJ
dti-1418	31	268	conversion	conversion	NOUN
dti-1418	31	269	of	of	ADP
dti-1418	31	270	recent	recent	ADJ
dti-1418	31	271	-	-	PUNCT
dti-1418	31	272	onset	onset	NOUN
dti-1418	31	273	af	af	NOUN
dti-1418	31	274	,	,	PUNCT
dti-1418	31	275	and	and	CCONJ
dti-1418	31	276	without	without	ADP
dti-1418	31	277	significant	significant	ADJ
dti-1418	31	278	adverse	adverse	ADJ
dti-1418	31	279	events.23–25	events.23–25	PUNCT
dti-1418	31	280	further	further	ADJ
dti-1418	31	281	studies	study	NOUN
dti-1418	31	282	showed	show	VERB
dti-1418	31	283	that	that	DET
dti-1418	31	284	vernakalant	vernakalant	NOUN
dti-1418	31	285	is	be	AUX
dti-1418	31	286	efficacious	efficacious	ADJ
dti-1418	31	287	in	in	ADP
dti-1418	31	288	converting	convert	VERB
dti-1418	31	289	recentonset	recentonset	NOUN
dti-1418	31	290	(	(	PUNCT
dti-1418	31	291	⩽7	⩽7	PROPN
dti-1418	31	292	days	day	NOUN
dti-1418	31	293	)	)	PUNCT
dti-1418	31	294	af	af	PROPN
dti-1418	31	295	;	;	PUNCT
dti-1418	31	296	also	also	ADV
dti-1418	31	297	it	it	PRON
dti-1418	31	298	is	be	AUX
dti-1418	31	299	efficacious	efficacious	ADJ
dti-1418	31	300	for	for	SCONJ
dti-1418	31	301	recent	recent	ADJ
dti-1418	31	302	-	-	PUNCT
dti-1418	31	303	onset	onset	NOUN
dti-1418	31	304	af	af	NOUN
dti-1418	31	305	(	(	PUNCT
dti-1418	31	306	⩽3	⩽3	NOUN
dti-1418	31	307	days	day	NOUN
dti-1418	31	308	)	)	PUNCT
dti-1418	31	309	occurring	occur	VERB
dti-1418	31	310	following	follow	VERB
dti-1418	31	311	heart	heart	NOUN
dti-1418	31	312	surgery.26,27	surgery.26,27	NOUN
dti-1418	31	313	in	in	ADP
dti-1418	31	314	the	the	DET
dti-1418	31	315	avro	avro	PROPN
dti-1418	31	316	study	study	NOUN
dti-1418	31	317	,	,	PUNCT
dti-1418	31	318	vernakalant	vernakalant	NOUN
dti-1418	31	319	demonstrated	demonstrate	VERB
dti-1418	31	320	superior	superior	ADJ
dti-1418	31	321	efficacy	efficacy	NOUN
dti-1418	31	322	compared	compare	VERB
dti-1418	31	323	with	with	ADP
dti-1418	31	324	amiodarone	amiodarone	NOUN
dti-1418	31	325	for	for	ADP
dti-1418	31	326	acute	acute	ADJ
dti-1418	31	327	conversion	conversion	NOUN
dti-1418	31	328	of	of	ADP
dti-1418	31	329	recent	recent	ADJ
dti-1418	31	330	-	-	PUNCT
dti-1418	31	331	onset	onset	NOUN
dti-1418	31	332	af	af	NOUN
dti-1418	31	333	,	,	PUNCT
dti-1418	31	334	and	and	CCONJ
dti-1418	31	335	success	success	NOUN
dti-1418	31	336	rate	rate	NOUN
dti-1418	31	337	was	be	AUX
dti-1418	31	338	51.7	51.7	NUM
dti-1418	31	339	%	%	NOUN
dti-1418	31	340	,	,	PUNCT
dti-1418	31	341	with	with	ADP
dti-1418	31	342	a	a	DET
dti-1418	31	343	median	median	ADJ
dti-1418	31	344	time	time	NOUN
dti-1418	31	345	of	of	ADP
dti-1418	31	346	conversion	conversion	NOUN
dti-1418	31	347	of	of	ADP
dti-1418	31	348	11	11	NUM
dti-1418	31	349	min	min	NOUN
dti-1418	31	350	;	;	PUNCT
dti-1418	31	351	moreover	moreover	ADV
dti-1418	31	352	,	,	PUNCT
dti-1418	31	353	there	there	PRON
dti-1418	31	354	were	be	VERB
dti-1418	31	355	no	no	DET
dti-1418	31	356	significant	significant	ADJ
dti-1418	31	357	side	side	NOUN
dti-1418	31	358	effects	effect	NOUN
dti-1418	31	359	,	,	PUNCT
dti-1418	31	360	also	also	ADV
dti-1418	31	361	there	there	PRON
dti-1418	31	362	were	be	VERB
dti-1418	31	363	no	no	DET
dti-1418	31	364	cases	case	NOUN
dti-1418	31	365	of	of	ADP
dti-1418	31	366	ventricular	ventricular	ADJ
dti-1418	31	367	arrhythmia.28	arrhythmia.28	NOUN
dti-1418	31	368	table	table	NOUN
dti-1418	31	369	1	1	NUM
dti-1418	31	370	illustrates	illustrate	VERB
dti-1418	31	371	key	key	ADJ
dti-1418	31	372	studies	study	NOUN
dti-1418	31	373	addressing	address	VERB
dti-1418	31	374	vernakalant	vernakalant	NOUN
dti-1418	31	375	.	.	PUNCT
dti-1418	32	1	the	the	DET
dti-1418	32	2	2010	2010	NUM
dti-1418	32	3	guidelines	guideline	NOUN
dti-1418	32	4	for	for	ADP
dti-1418	32	5	the	the	DET
dti-1418	32	6	management	management	NOUN
dti-1418	32	7	of	of	ADP
dti-1418	32	8	af	af	PROPN
dti-1418	32	9	recommended	recommend	VERB
dti-1418	32	10	vernakalant	vernakalant	NOUN
dti-1418	32	11	for	for	ADP
dti-1418	32	12	approval	approval	NOUN
dti-1418	32	13	for	for	ADP
dti-1418	32	14	rapid	rapid	ADJ
dti-1418	32	15	cardioversion	cardioversion	NOUN
dti-1418	32	16	of	of	ADP
dti-1418	32	17	recent	recent	ADJ
dti-1418	32	18	-	-	PUNCT
dti-1418	32	19	onset	onset	NOUN
dti-1418	32	20	af	af	NOUN
dti-1418	32	21	to	to	ADP
dti-1418	32	22	sinus	sinus	NOUN
dti-1418	32	23	rhythm	rhythm	NOUN
dti-1418	32	24	in	in	ADP
dti-1418	32	25	adults.14	adults.14	PROPN
dti-1418	32	26	the	the	DET
dti-1418	32	27	2012	2012	NUM
dti-1418	32	28	focused	focused	ADJ
dti-1418	32	29	update	update	NOUN
dti-1418	32	30	of	of	ADP
dti-1418	32	31	the	the	DET
dti-1418	32	32	2010	2010	NUM
dti-1418	32	33	esc	esc	NOUN
dti-1418	32	34	guidelines	guideline	NOUN
dti-1418	32	35	stated	state	VERB
dti-1418	32	36	that	that	DET
dti-1418	32	37	vernakalant	vernakalant	NOUN
dti-1418	32	38	should	should	AUX
dti-1418	32	39	be	be	AUX
dti-1418	32	40	considered	consider	VERB
dti-1418	32	41	for	for	ADP
dti-1418	32	42	recent	recent	ADJ
dti-1418	32	43	-	-	PUNCT
dti-1418	32	44	onset	onset	NOUN
dti-1418	32	45	af	af	PROPN
dti-1418	32	46	(	(	PUNCT
dti-1418	32	47	⩽7	⩽7	PROPN
dti-1418	32	48	days	day	NOUN
dti-1418	32	49	)	)	PUNCT
dti-1418	32	50	in	in	ADP
dti-1418	32	51	patients	patient	NOUN
dti-1418	32	52	with	with	ADP
dti-1418	32	53	mild	mild	ADJ
dti-1418	32	54	or	or	CCONJ
dti-1418	32	55	moderate	moderate	ADJ
dti-1418	32	56	structural	structural	ADJ
dti-1418	32	57	heart	heart	NOUN
dti-1418	32	58	disease	disease	NOUN
dti-1418	32	59	(	(	PUNCT
dti-1418	32	60	class	class	NOUN
dti-1418	32	61	iib	iib	NOUN
dti-1418	32	62	,	,	PUNCT
dti-1418	32	63	level	level	NOUN
dti-1418	32	64	b	b	NOUN
dti-1418	32	65	)	)	PUNCT
dti-1418	32	66	;	;	PUNCT
dti-1418	32	67	also	also	ADV
dti-1418	32	68	vernakalant	vernakalant	NOUN
dti-1418	32	69	may	may	AUX
dti-1418	32	70	be	be	AUX
dti-1418	32	71	considered	consider	VERB
dti-1418	32	72	for	for	ADP
dti-1418	32	73	recent	recent	ADJ
dti-1418	32	74	-	-	PUNCT
dti-1418	32	75	onset	onset	NOUN
dti-1418	32	76	af	af	NOUN
dti-1418	32	77	post	post	VERB
dti-1418	32	78	cardiac	cardiac	ADJ
dti-1418	32	79	surgery	surgery	NOUN
dti-1418	32	80	(	(	PUNCT
dti-1418	32	81	⩽3	⩽3	NOUN
dti-1418	32	82	days	day	NOUN
dti-1418	32	83	)	)	PUNCT
dti-1418	32	84	(	(	PUNCT
dti-1418	32	85	class	class	NOUN
dti-1418	32	86	iib	iib	NOUN
dti-1418	32	87	,	,	PUNCT
dti-1418	32	88	level	level	NOUN
dti-1418	32	89	b).34	b).34	NOUN
dti-1418	32	90	the	the	DET
dti-1418	32	91	2016	2016	NUM
dti-1418	32	92	esc	esc	NOUN
dti-1418	32	93	guidelines	guideline	NOUN
dti-1418	32	94	for	for	ADP
dti-1418	32	95	the	the	DET
dti-1418	32	96	management	management	NOUN
dti-1418	32	97	of	of	ADP
dti-1418	32	98	af3	af3	NOUN
dti-1418	32	99	recommended	recommend	VERB
dti-1418	32	100	vernakalant	vernakalant	NOUN
dti-1418	32	101	for	for	ADP
dti-1418	32	102	pharmacological	pharmacological	ADJ
dti-1418	32	103	cardioversion	cardioversion	NOUN
dti-1418	32	104	(	(	PUNCT
dti-1418	32	105	rhythm	rhythm	PROPN
dti-1418	32	106	control	control	NOUN
dti-1418	32	107	)	)	PUNCT
dti-1418	32	108	of	of	ADP
dti-1418	32	109	recent	recent	ADJ
dti-1418	32	110	-	-	PUNCT
dti-1418	32	111	onset	onset	NOUN
dti-1418	32	112	af	af	NOUN
dti-1418	32	113	,	,	PUNCT
dti-1418	32	114	in	in	ADP
dti-1418	32	115	patients	patient	NOUN
dti-1418	32	116	with	with	ADP
dti-1418	32	117	no	no	DET
dti-1418	32	118	history	history	NOUN
dti-1418	32	119	of	of	ADP
dti-1418	32	120	ischemic	ischemic	ADJ
dti-1418	32	121	or	or	CCONJ
dti-1418	32	122	structural	structural	ADJ
dti-1418	32	123	heart	heart	NOUN
dti-1418	32	124	disease	disease	NOUN
dti-1418	32	125	(	(	PUNCT
dti-1418	32	126	recommendation	recommendation	NOUN
dti-1418	32	127	:	:	PUNCT
dti-1418	32	128	class	class	NOUN
dti-1418	32	129	i	i	PROPN
dti-1418	32	130	,	,	PUNCT
dti-1418	32	131	level	level	NOUN
dti-1418	32	132	a	a	PRON
dti-1418	32	133	)	)	PUNCT
dti-1418	32	134	.	.	PUNCT
dti-1418	33	1	according	accord	VERB
dti-1418	33	2	to	to	ADP
dti-1418	33	3	the	the	DET
dti-1418	33	4	same	same	ADJ
dti-1418	33	5	study,3	study,3	NOUN
dti-1418	33	6	vernakalant	vernakalant	NOUN
dti-1418	33	7	may	may	AUX
dti-1418	33	8	be	be	AUX
dti-1418	33	9	considered	consider	VERB
dti-1418	33	10	as	as	ADP
dti-1418	33	11	alternative	alternative	ADJ
dti-1418	33	12	to	to	PART
dti-1418	33	13	amiodarone	amiodarone	VERB
dti-1418	33	14	in	in	ADP
dti-1418	33	15	patients	patient	NOUN
dti-1418	33	16	with	with	ADP
dti-1418	33	17	stable	stable	ADJ
dti-1418	33	18	ischemic	ischemic	ADJ
dti-1418	33	19	and/or	and/or	CCONJ
dti-1418	33	20	moderate	moderate	ADJ
dti-1418	33	21	structural	structural	ADJ
dti-1418	33	22	heart	heart	NOUN
dti-1418	33	23	disease	disease	NOUN
dti-1418	33	24	,	,	PUNCT
dti-1418	33	25	including	include	VERB
dti-1418	33	26	mild	mild	ADJ
dti-1418	33	27	to	to	ADP
dti-1418	33	28	moderate	moderate	ADJ
dti-1418	33	29	heart	heart	NOUN
dti-1418	33	30	failure	failure	NOUN
dti-1418	33	31	(	(	PUNCT
dti-1418	33	32	class	class	NOUN
dti-1418	33	33	ii	ii	PROPN
dti-1418	33	34	,	,	PUNCT
dti-1418	33	35	level	level	NOUN
dti-1418	33	36	b	b	NOUN
dti-1418	33	37	)	)	PUNCT
dti-1418	33	38	.	.	PUNCT
dti-1418	34	1	figure	figure	NOUN
dti-1418	34	2	1	1	NUM
dti-1418	34	3	illustrates	illustrate	VERB
dti-1418	34	4	these	these	DET
dti-1418	34	5	clinical	clinical	ADJ
dti-1418	34	6	scenario	scenario	NOUN
dti-1418	34	7	.	.	PUNCT
dti-1418	35	1	in	in	ADP
dti-1418	35	2	a	a	DET
dti-1418	35	3	randomized	randomized	ADJ
dti-1418	35	4	controlled	control	VERB
dti-1418	35	5	trial	trial	NOUN
dti-1418	35	6	including	include	VERB
dti-1418	35	7	100	100	NUM
dti-1418	35	8	patients	patient	NOUN
dti-1418	35	9	with	with	ADP
dti-1418	35	10	recent	recent	ADJ
dti-1418	35	11	-	-	PUNCT
dti-1418	35	12	onset	onset	NOUN
dti-1418	35	13	af	af	NOUN
dti-1418	35	14	,	,	PUNCT
dti-1418	35	15	vernakalant	vernakalant	NOUN
dti-1418	35	16	was	be	AUX
dti-1418	35	17	superior	superior	ADJ
dti-1418	35	18	to	to	PART
dti-1418	35	19	ibutilide	ibutilide	VERB
dti-1418	35	20	in	in	ADP
dti-1418	35	21	converting	convert	VERB
dti-1418	35	22	af	af	NOUN
dti-1418	35	23	to	to	ADP
dti-1418	35	24	sinus	sinus	NOUN
dti-1418	35	25	rhythm	rhythm	NOUN
dti-1418	35	26	(	(	PUNCT
dti-1418	35	27	shorter	short	ADJ
dti-1418	35	28	time	time	NOUN
dti-1418	35	29	to	to	PART
dti-1418	35	30	conversion	conversion	VERB
dti-1418	35	31	to	to	ADP
dti-1418	35	32	sinus	sinus	NOUN
dti-1418	35	33	rhythm	rhythm	NOUN
dti-1418	35	34	and	and	CCONJ
dti-1418	35	35	higher	high	ADJ
dti-1418	35	36	conversion	conversion	NOUN
dti-1418	35	37	rate	rate	NOUN
dti-1418	35	38	at	at	ADP
dti-1418	35	39	90	90	NUM
dti-1418	35	40	min).30	min).30	NOUN
dti-1418	35	41	of	of	ADP
dti-1418	35	42	note	note	NOUN
dti-1418	35	43	,	,	PUNCT
dti-1418	35	44	vernakalant	vernakalant	NOUN
dti-1418	35	45	is	be	AUX
dti-1418	35	46	significantly	significantly	ADV
dti-1418	35	47	more	more	ADV
dti-1418	35	48	expensive	expensive	ADJ
dti-1418	35	49	when	when	SCONJ
dti-1418	35	50	compared	compare	VERB
dti-1418	35	51	with	with	ADP
dti-1418	35	52	ibutilide	ibutilide	NOUN
dti-1418	35	53	;	;	PUNCT
dti-1418	35	54	however	however	ADV
dti-1418	35	55	,	,	PUNCT
dti-1418	35	56	fewer	few	ADJ
dti-1418	35	57	side	side	NOUN
dti-1418	35	58	effects	effect	NOUN
dti-1418	35	59	and	and	CCONJ
dti-1418	35	60	more	more	ADV
dti-1418	35	61	rapid	rapid	ADJ
dti-1418	35	62	restoration	restoration	NOUN
dti-1418	35	63	of	of	ADP
dti-1418	35	64	sinus	sinus	NOUN
dti-1418	35	65	rhythm	rhythm	NOUN
dti-1418	35	66	are	be	AUX
dti-1418	35	67	observed	observe	VERB
dti-1418	35	68	with	with	ADP
dti-1418	35	69	vernakalant	vernakalant	NOUN
dti-1418	35	70	,	,	PUNCT
dti-1418	35	71	reducing	reduce	VERB
dti-1418	35	72	the	the	DET
dti-1418	35	73	overall	overall	ADJ
dti-1418	35	74	cost	cost	NOUN
dti-1418	35	75	of	of	ADP
dti-1418	35	76	hospitalization	hospitalization	NOUN
dti-1418	35	77	in	in	ADP
dti-1418	35	78	recent	recent	ADJ
dti-1418	35	79	-	-	PUNCT
dti-1418	35	80	onset	onset	NOUN
dti-1418	35	81	af	af	NOUN
dti-1418	35	82	patients.35	patients.35	PROPN
dti-1418	35	83	in	in	ADP
dti-1418	35	84	a	a	DET
dti-1418	35	85	meta	meta	ADJ
dti-1418	35	86	-	-	PUNCT
dti-1418	35	87	analysis	analysis	NOUN
dti-1418	35	88	conducted	conduct	VERB
dti-1418	35	89	by	by	ADP
dti-1418	35	90	bash	bash	NOUN
dti-1418	35	91	et	et	NOUN
dti-1418	35	92	 	 	SPACE
dti-1418	35	93	al	al	PROPN
dti-1418	35	94	,	,	PUNCT
dti-1418	35	95	the	the	DET
dti-1418	35	96	efficacy	efficacy	NOUN
dti-1418	35	97	of	of	ADP
dti-1418	35	98	cardioversion	cardioversion	NOUN
dti-1418	35	99	of	of	ADP
dti-1418	35	100	recent	recent	ADJ
dti-1418	35	101	-	-	PUNCT
dti-1418	35	102	onset	onset	NOUN
dti-1418	35	103	af	af	NOUN
dti-1418	35	104	by	by	ADP
dti-1418	35	105	vernakalant	vernakalant	NOUN
dti-1418	35	106	and	and	CCONJ
dti-1418	35	107	by	by	ADP
dti-1418	35	108	“	"	PUNCT
dti-1418	35	109	comparators	comparator	NOUN
dti-1418	35	110	”	"	PUNCT
dti-1418	35	111	(	(	PUNCT
dti-1418	35	112	propafenone	propafenone	NOUN
dti-1418	35	113	and	and	CCONJ
dti-1418	35	114	flecainide	flecainide	NOUN
dti-1418	35	115	)	)	PUNCT
dti-1418	35	116	was	be	AUX
dti-1418	35	117	studied	study	VERB
dti-1418	35	118	,	,	PUNCT
dti-1418	35	119	and	and	CCONJ
dti-1418	35	120	the	the	DET
dti-1418	35	121	authors	author	NOUN
dti-1418	35	122	concluded	conclude	VERB
dti-1418	35	123	that	that	SCONJ
dti-1418	35	124	all	all	DET
dti-1418	35	125	these	these	DET
dti-1418	35	126	aads	aad	NOUN
dti-1418	35	127	are	be	AUX
dti-1418	35	128	efficient	efficient	ADJ
dti-1418	35	129	for	for	ADP
dti-1418	35	130	rapid	rapid	ADJ
dti-1418	35	131	restoration	restoration	NOUN
dti-1418	35	132	of	of	ADP
dti-1418	35	133	sinus	sinus	NOUN
dti-1418	35	134	rhythm	rhythm	NOUN
dti-1418	35	135	;	;	PUNCT
dti-1418	35	136	however	however	ADV
dti-1418	35	137	,	,	PUNCT
dti-1418	35	138	there	there	PRON
dti-1418	35	139	was	be	VERB
dti-1418	35	140	no	no	DET
dti-1418	35	141	mention	mention	NOUN
dti-1418	35	142	regarding	regard	VERB
dti-1418	35	143	the	the	DET
dti-1418	35	144	time	time	NOUN
dti-1418	35	145	to	to	ADP
dti-1418	35	146	conversion	conversion	NOUN
dti-1418	35	147	observed	observe	VERB
dti-1418	35	148	with	with	ADP
dti-1418	35	149	each	each	DET
dti-1418	35	150	drug.36	drug.36	NOUN
dti-1418	35	151	when	when	SCONJ
dti-1418	35	152	compared	compare	VERB
dti-1418	35	153	head	head	NOUN
dti-1418	35	154	-	-	PUNCT
dti-1418	35	155	to	to	ADP
dti-1418	35	156	-	-	PUNCT
dti-1418	35	157	head	head	NOUN
dti-1418	35	158	with	with	ADP
dti-1418	35	159	flecainide	flecainide	NOUN
dti-1418	35	160	in	in	ADP
dti-1418	35	161	patients	patient	NOUN
dti-1418	35	162	with	with	ADP
dti-1418	35	163	recent	recent	ADJ
dti-1418	35	164	-	-	PUNCT
dti-1418	35	165	onset	onset	NOUN
dti-1418	35	166	af	af	NOUN
dti-1418	35	167	,	,	PUNCT
dti-1418	35	168	vernakalant	vernakalant	NOUN
dti-1418	35	169	was	be	AUX
dti-1418	35	170	more	more	ADV
dti-1418	35	171	effective	effective	ADJ
dti-1418	35	172	in	in	ADP
dti-1418	35	173	cardio	cardio	NOUN
dti-1418	35	174	version	version	NOUN
dti-1418	35	175	to	to	ADP
dti-1418	35	176	sinus	sinus	NOUN
dti-1418	35	177	rhythm	rhythm	NOUN
dti-1418	35	178	;	;	PUNCT
dti-1418	35	179	moreover	moreover	ADV
dti-1418	35	180	,	,	PUNCT
dti-1418	35	181	vernakalant	vernakalant	NOUN
dti-1418	35	182	allowed	allow	VERB
dti-1418	35	183	faster	fast	ADJ
dti-1418	35	184	restoration	restoration	NOUN
dti-1418	35	185	of	of	ADP
dti-1418	35	186	sinus	sinus	NOUN
dti-1418	35	187	rhythm	rhythm	NOUN
dti-1418	35	188	,	,	PUNCT
dti-1418	35	189	and	and	CCONJ
dti-1418	35	190	therefore	therefore	ADV
dti-1418	35	191	,	,	PUNCT
dti-1418	35	192	patients	patient	NOUN
dti-1418	35	193	can	can	AUX
dti-1418	35	194	be	be	AUX
dti-1418	35	195	discharged	discharge	VERB
dti-1418	35	196	earlier	early	ADV
dti-1418	35	197	from	from	ADP
dti-1418	35	198	the	the	DET
dti-1418	35	199	emergency	emergency	NOUN
dti-1418	35	200	department.33,37	department.33,37	NOUN
dti-1418	35	201	similarly	similarly	ADV
dti-1418	35	202	,	,	PUNCT
dti-1418	35	203	when	when	SCONJ
dti-1418	35	204	compared	compare	VERB
dti-1418	35	205	head	head	NOUN
dti-1418	35	206	-	-	PUNCT
dti-1418	35	207	to	to	ADP
dti-1418	35	208	-	-	PUNCT
dti-1418	35	209	head	head	NOUN
dti-1418	35	210	with	with	ADP
dti-1418	35	211	propafenone	propafenone	NOUN
dti-1418	35	212	in	in	ADP
dti-1418	35	213	patients	patient	NOUN
dti-1418	35	214	with	with	ADP
dti-1418	35	215	recent	recent	ADJ
dti-1418	35	216	-	-	PUNCT
dti-1418	35	217	onset	onset	NOUN
dti-1418	35	218	af	af	NOUN
dti-1418	35	219	,	,	PUNCT
dti-1418	35	220	vernakalant	vernakalant	NOUN
dti-1418	35	221	showed	show	VERB
dti-1418	35	222	higher	high	ADJ
dti-1418	35	223	efficacy	efficacy	NOUN
dti-1418	35	224	and	and	CCONJ
dti-1418	35	225	a	a	DET
dti-1418	35	226	shorter	short	ADJ
dti-1418	35	227	time	time	NOUN
dti-1418	35	228	to	to	ADP
dti-1418	35	229	conversion	conversion	NOUN
dti-1418	35	230	of	of	ADP
dti-1418	35	231	af	af	NOUN
dti-1418	35	232	to	to	ADP
dti-1418	35	233	sinus	sinus	NOUN
dti-1418	35	234	rhythm	rhythm	NOUN
dti-1418	35	235	and	and	CCONJ
dti-1418	35	236	was	be	AUX
dti-1418	35	237	associated	associate	VERB
dti-1418	35	238	with	with	ADP
dti-1418	35	239	shorter	short	ADJ
dti-1418	35	240	hospital	hospital	NOUN
dti-1418	35	241	stay.29	stay.29	NOUN
dti-1418	35	242	vernakalant	vernakalant	NOUN
dti-1418	35	243	is	be	AUX
dti-1418	35	244	usually	usually	ADV
dti-1418	35	245	a	a	DET
dti-1418	35	246	well	well	ADV
dti-1418	35	247	-	-	PUNCT
dti-1418	35	248	tolerated	tolerate	VERB
dti-1418	35	249	drug	drug	NOUN
dti-1418	35	250	and	and	CCONJ
dti-1418	35	251	most	most	ADV
dti-1418	35	252	common	common	ADJ
dti-1418	35	253	side	side	NOUN
dti-1418	35	254	effects	effect	NOUN
dti-1418	35	255	include	include	VERB
dti-1418	35	256	paresthesia	paresthesia	NOUN
dti-1418	35	257	,	,	PUNCT
dti-1418	35	258	dysgeusia	dysgeusia	NOUN
dti-1418	35	259	,	,	PUNCT
dti-1418	35	260	dizziness	dizziness	NOUN
dti-1418	35	261	,	,	PUNCT
dti-1418	35	262	sneezing	sneezing	NOUN
dti-1418	35	263	,	,	PUNCT
dti-1418	35	264	and	and	CCONJ
dti-1418	35	265	nausea	nausea	NOUN
dti-1418	35	266	and	and	CCONJ
dti-1418	35	267	these	these	DET
dti-1418	35	268	effects	effect	NOUN
dti-1418	35	269	are	be	AUX
dti-1418	35	270	probably	probably	ADV
dti-1418	35	271	related	relate	VERB
dti-1418	35	272	to	to	ADP
dti-1418	35	273	the	the	DET
dti-1418	35	274	inhibition	inhibition	NOUN
dti-1418	35	275	of	of	ADP
dti-1418	35	276	the	the	DET
dti-1418	35	277	sodium	sodium	NOUN
dti-1418	35	278	channels	channel	NOUN
dti-1418	35	279	in	in	ADP
dti-1418	35	280	the	the	DET
dti-1418	35	281	central	central	ADJ
dti-1418	35	282	nervous	nervous	ADJ
dti-1418	35	283	system	system	NOUN
dti-1418	35	284	;	;	PUNCT
dti-1418	35	285	also	also	ADV
dti-1418	35	286	most	most	ADJ
dti-1418	35	287	of	of	ADP
dti-1418	35	288	these	these	DET
dti-1418	35	289	side	side	NOUN
dti-1418	35	290	effects	effect	NOUN
dti-1418	35	291	are	be	AUX
dti-1418	35	292	mild	mild	ADJ
dti-1418	35	293	and	and	CCONJ
dti-1418	35	294	transient.38	transient.38	PROPN
dti-1418	35	295	of	of	ADP
dti-1418	35	296	note	note	NOUN
dti-1418	35	297	,	,	PUNCT
dti-1418	35	298	de	de	X
dti-1418	35	299	riva	riva	NOUN
dti-1418	35	300	-	-	PUNCT
dti-1418	35	301	silva	silva	PROPN
dti-1418	35	302	et	et	NOUN
dti-1418	35	303	 	 	SPACE
dti-1418	35	304	al39	al39	PROPN
dti-1418	35	305	reported	report	VERB
dti-1418	35	306	a	a	DET
dti-1418	35	307	case	case	NOUN
dti-1418	35	308	of	of	ADP
dti-1418	35	309	1:1	1:1	NUM
dti-1418	35	310	av	av	PROPN
dti-1418	35	311	conduction	conduction	NOUN
dti-1418	35	312	atrial	atrial	ADJ
dti-1418	35	313	flutter	flutter	NOUN
dti-1418	35	314	after	after	ADP
dti-1418	35	315	vernakalant	vernakalant	NOUN
dti-1418	35	316	administration	administration	NOUN
dti-1418	35	317	for	for	ADP
dti-1418	35	318	af	af	PROPN
dti-1418	35	319	conversion	conversion	PROPN
dti-1418	35	320	;	;	PUNCT
dti-1418	35	321	however	however	ADV
dti-1418	35	322	,	,	PUNCT
dti-1418	35	323	guerra	guerra	PROPN
dti-1418	35	324	et	et	PROPN
dti-1418	35	325	 	 	SPACE
dti-1418	35	326	al38	al38	PROPN
dti-1418	35	327	reported	report	VERB
dti-1418	35	328	that	that	SCONJ
dti-1418	35	329	no	no	DET
dti-1418	35	330	cases	case	NOUN
dti-1418	35	331	of	of	ADP
dti-1418	35	332	significant	significant	ADJ
dti-1418	35	333	arrhythmia	arrhythmia	NOUN
dti-1418	35	334	or	or	CCONJ
dti-1418	35	335	hemodynamic	hemodynamic	ADJ
dti-1418	35	336	dysfunction	dysfunction	NOUN
dti-1418	35	337	are	be	AUX
dti-1418	35	338	generally	generally	ADV
dti-1418	35	339	observed	observe	VERB
dti-1418	35	340	when	when	SCONJ
dti-1418	35	341	cautions	caution	NOUN
dti-1418	35	342	and	and	CCONJ
dti-1418	35	343	contraindications	contraindication	NOUN
dti-1418	35	344	are	be	AUX
dti-1418	35	345	respected	respect	VERB
dti-1418	35	346	.	.	PUNCT
dti-1418	36	1	vernakalant	vernakalant	NOUN
dti-1418	36	2	is	be	AUX
dti-1418	36	3	contraindicated	contraindicate	VERB
dti-1418	36	4	in	in	ADP
dti-1418	36	5	patients	patient	NOUN
dti-1418	36	6	with	with	ADP
dti-1418	36	7	hypersensitivity	hypersensitivity	NOUN
dti-1418	36	8	to	to	ADP
dti-1418	36	9	the	the	DET
dti-1418	36	10	drug	drug	NOUN
dti-1418	36	11	,	,	PUNCT
dti-1418	36	12	high	high	ADJ
dti-1418	36	13	-	-	PUNCT
dti-1418	36	14	grade	grade	NOUN
dti-1418	36	15	av	av	NOUN
dti-1418	36	16	block	block	NOUN
dti-1418	36	17	which	which	PRON
dti-1418	36	18	is	be	AUX
dti-1418	36	19	not	not	PART
dti-1418	36	20	backed	back	VERB
dti-1418	36	21	up	up	ADP
dti-1418	36	22	by	by	ADP
dti-1418	36	23	pacemaker	pacemaker	NOUN
dti-1418	36	24	,	,	PUNCT
dti-1418	36	25	hypotension	hypotension	NOUN
dti-1418	36	26	as	as	SCONJ
dti-1418	36	27	defined	define	VERB
dti-1418	36	28	by	by	ADP
dti-1418	36	29	systolic	systolic	ADJ
dti-1418	36	30	blood	blood	NOUN
dti-1418	36	31	pressure	pressure	NOUN
dti-1418	36	32	less	less	ADJ
dti-1418	36	33	than	than	ADP
dti-1418	36	34	100	100	NUM
dti-1418	36	35	mm	mm	NUM
dti-1418	36	36	hg	hg	NOUN
dti-1418	36	37	,	,	PUNCT
dti-1418	36	38	recent	recent	ADJ
dti-1418	36	39	(	(	PUNCT
dti-1418	36	40	<	<	X
dti-1418	36	41	30	30	NUM
dti-1418	36	42	days	day	NOUN
dti-1418	36	43	)	)	PUNCT
dti-1418	36	44	acute	acute	ADJ
dti-1418	36	45	coronary	coronary	ADJ
dti-1418	36	46	syndrome	syndrome	NOUN
dti-1418	36	47	,	,	PUNCT
dti-1418	36	48	heart	heart	NOUN
dti-1418	36	49	failure	failure	NOUN
dti-1418	36	50	with	with	ADP
dti-1418	36	51	nyha	nyha	NOUN
dti-1418	36	52	class	class	PROPN
dti-1418	36	53	iii	iii	PROPN
dti-1418	36	54	and	and	CCONJ
dti-1418	36	55	iv	iv	NUM
dti-1418	36	56	,	,	PUNCT
dti-1418	36	57	severe	severe	ADJ
dti-1418	36	58	aortic	aortic	ADJ
dti-1418	36	59	stenosis	stenosis	NOUN
dti-1418	36	60	,	,	PUNCT
dti-1418	36	61	and	and	CCONJ
dti-1418	36	62	long	long	ADJ
dti-1418	36	63	qt	qt	NOUN
dti-1418	36	64	interval	interval	NOUN
dti-1418	36	65	;	;	PUNCT
dti-1418	36	66	also	also	ADV
dti-1418	36	67	vernakalant	vernakalant	NOUN
dti-1418	36	68	is	be	AUX
dti-1418	36	69	contraindicated	contraindicate	VERB
dti-1418	36	70	within	within	ADP
dti-1418	36	71	4	4	NUM
dti-1418	36	72	h	h	NOUN
dti-1418	36	73	after	after	ADP
dti-1418	36	74	use	use	NOUN
dti-1418	36	75	of	of	ADP
dti-1418	36	76	amiodarone	amiodarone	NOUN
dti-1418	36	77	(	(	PUNCT
dti-1418	36	78	oral	oral	ADJ
dti-1418	36	79	or	or	CCONJ
dti-1418	36	80	iv).34,38	iv).34,38	ADJ
dti-1418	36	81	vernakalant	vernakalant	NOUN
dti-1418	36	82	did	do	AUX
dti-1418	36	83	not	not	PART
dti-1418	36	84	restore	restore	VERB
dti-1418	36	85	sinus	sinus	NOUN
dti-1418	36	86	rhythm	rhythm	NOUN
dti-1418	36	87	in	in	ADP
dti-1418	36	88	patients	patient	NOUN
dti-1418	36	89	with	with	ADP
dti-1418	36	90	atrial	atrial	ADJ
dti-1418	36	91	flutter	flutter	NOUN
dti-1418	36	92	in	in	ADP
dti-1418	36	93	act	act	PROPN
dti-1418	36	94	ii	ii	PROPN
dti-1418	36	95	and	and	CCONJ
dti-1418	36	96	act	act	VERB
dti-1418	36	97	iii	iii	NUM
dti-1418	36	98	trials,24,25	trials,24,25	PROPN
dti-1418	36	99	and	and	CCONJ
dti-1418	36	100	only	only	ADV
dti-1418	36	101	a	a	DET
dti-1418	36	102	reduced	reduce	VERB
dti-1418	36	103	mean	mean	ADJ
dti-1418	36	104	ventricular	ventricular	ADJ
dti-1418	36	105	response	response	NOUN
dti-1418	36	106	rate	rate	NOUN
dti-1418	36	107	was	be	AUX
dti-1418	36	108	mostly	mostly	ADV
dti-1418	36	109	observed	observe	VERB
dti-1418	36	110	in	in	ADP
dti-1418	36	111	the	the	DET
dti-1418	36	112	studied	studied	ADJ
dti-1418	36	113	patients	patient	NOUN
dti-1418	36	114	.	.	PUNCT
dti-1418	37	1	vernakalant	vernakalant	NOUN
dti-1418	37	2	has	have	AUX
dti-1418	37	3	rate	rate	VERB
dti-1418	37	4	related	relate	VERB
dti-1418	37	5	blocking	blocking	NOUN
dti-1418	37	6	effects	effect	NOUN
dti-1418	37	7	on	on	ADP
dti-1418	37	8	sodium	sodium	NOUN
dti-1418	37	9	channels	channel	NOUN
dti-1418	37	10	(	(	PUNCT
dti-1418	37	11	ina	ina	PROPN
dti-1418	37	12	)	)	PUNCT
dti-1418	37	13	,	,	PUNCT
dti-1418	37	14	which	which	PRON
dti-1418	37	15	is	be	AUX
dti-1418	37	16	the	the	DET
dti-1418	37	17	probable	probable	ADJ
dti-1418	37	18	explanation	explanation	NOUN
dti-1418	37	19	for	for	ADP
dti-1418	37	20	the	the	DET
dti-1418	37	21	lack	lack	NOUN
dti-1418	37	22	of	of	ADP
dti-1418	37	23	efficacy	efficacy	NOUN
dti-1418	37	24	on	on	ADP
dti-1418	37	25	atrial	atrial	ADJ
dti-1418	37	26	flutter	flutter	NOUN
dti-1418	37	27	patients	patient	NOUN
dti-1418	37	28	;	;	PUNCT
dti-1418	37	29	of	of	ADP
dti-1418	37	30	note	note	NOUN
dti-1418	37	31	,	,	PUNCT
dti-1418	37	32	no	no	DET
dti-1418	37	33	cases	case	NOUN
dti-1418	37	34	of	of	ADP
dti-1418	37	35	1:1	1:1	NUM
dti-1418	37	36	av	av	PROPN
dti-1418	37	37	conduction	conduction	NOUN
dti-1418	37	38	with	with	ADP
dti-1418	37	39	rapid	rapid	ADJ
dti-1418	37	40	ventricular	ventricular	ADJ
dti-1418	37	41	response	response	NOUN
dti-1418	37	42	are	be	AUX
dti-1418	37	43	observed	observe	VERB
dti-1418	37	44	when	when	SCONJ
dti-1418	37	45	vernakalant	vernakalant	NOUN
dti-1418	37	46	is	be	AUX
dti-1418	37	47	used	use	VERB
dti-1418	37	48	in	in	ADP
dti-1418	37	49	atrial	atrial	ADJ
dti-1418	37	50	flutter.40	flutter.40	PROPN
dti-1418	37	51	oral	oral	ADJ
dti-1418	37	52	vernakalant	vernakalant	NOUN
dti-1418	37	53	(	(	PUNCT
dti-1418	37	54	150	150	NUM
dti-1418	37	55	,	,	PUNCT
dti-1418	37	56	300	300	NUM
dti-1418	37	57	,	,	PUNCT
dti-1418	37	58	and	and	CCONJ
dti-1418	37	59	500	500	NUM
dti-1418	37	60	mg	mg	NOUN
dti-1418	37	61	)	)	PUNCT
dti-1418	37	62	was	be	AUX
dti-1418	37	63	studied	study	VERB
dti-1418	37	64	in	in	ADP
dti-1418	37	65	a	a	DET
dti-1418	37	66	single	single	ADJ
dti-1418	37	67	phase	phase	NOUN
dti-1418	37	68	iib	iib	NOUN
dti-1418	37	69	trial	trial	NOUN
dti-1418	37	70	as	as	ADP
dti-1418	37	71	a	a	DET
dti-1418	37	72	prophylactic	prophylactic	ADJ
dti-1418	37	73	drug	drug	NOUN
dti-1418	37	74	for	for	ADP
dti-1418	37	75	sinus	sinus	NOUN
dti-1418	37	76	rhythm	rhythm	NOUN
dti-1418	37	77	maintenance	maintenance	NOUN
dti-1418	37	78	after	after	SCONJ
dti-1418	37	79	direct	direct	ADJ
dti-1418	37	80	current	current	ADJ
dti-1418	37	81	cardioversion;41	cardioversion;41	NOUN
dti-1418	37	82	the	the	DET
dti-1418	37	83	150	150	NUM
dti-1418	37	84	and	and	CCONJ
dti-1418	37	85	300	300	NUM
dti-1418	37	86	mg	mg	NOUN
dti-1418	37	87	doses	dose	NOUN
dti-1418	37	88	did	do	AUX
dti-1418	37	89	not	not	PART
dti-1418	37	90	show	show	VERB
dti-1418	37	91	superiority	superiority	NOUN
dti-1418	37	92	against	against	ADP
dti-1418	37	93	placebo	placebo	NOUN
dti-1418	37	94	,	,	PUNCT
dti-1418	37	95	and	and	CCONJ
dti-1418	37	96	4	4	NUM
dti-1418	37	97	drug	drug	NOUN
dti-1418	37	98	target	target	NOUN
dti-1418	37	99	insights	insight	NOUN
dti-1418	37	100	table	table	VERB
dti-1418	37	101	1	1	NUM
dti-1418	37	102	.	.	PUNCT
dti-1418	37	103	main	main	ADJ
dti-1418	37	104	studies	study	NOUN
dti-1418	37	105	addressing	address	VERB
dti-1418	37	106	vernakalant	vernakalant	NOUN
dti-1418	37	107	.	.	PUNCT
dti-1418	38	1	study	study	NOUN
dti-1418	38	2	/	/	SYM
dti-1418	38	3	author	author	NOUN
dti-1418	38	4	/	/	SYM
dti-1418	38	5	design	design	NOUN
dti-1418	38	6	/	/	SYM
dti-1418	38	7	objective	objective	ADJ
dti-1418	38	8	date	date	NOUN
dti-1418	38	9	patients	patient	NOUN
dti-1418	38	10	conversion	conversion	NOUN
dti-1418	38	11	rate	rate	NOUN
dti-1418	38	12	results	result	NOUN
dti-1418	38	13	regarding	regard	VERB
dti-1418	38	14	vernakalant	vernakalant	NOUN
dti-1418	38	15	craft12	craft12	NOUN
dti-1418	38	16	multi	multi	ADJ
dti-1418	38	17	-	-	ADJ
dti-1418	38	18	centered	centered	ADJ
dti-1418	38	19	,	,	PUNCT
dti-1418	38	20	randomized	randomize	VERB
dti-1418	38	21	,	,	PUNCT
dti-1418	38	22	doubleblinded	doubleblinde	VERB
dti-1418	38	23	(	(	PUNCT
dti-1418	38	24	vkl	vkl	NOUN
dti-1418	38	25	vs	vs	ADP
dti-1418	38	26	placebo	placebo	NOUN
dti-1418	38	27	)	)	PUNCT
dti-1418	38	28	2004	2004	NUM
dti-1418	38	29	56	56	NUM
dti-1418	38	30	pts	pts	ADP
dti-1418	38	31	recent	recent	ADJ
dti-1418	38	32	-	-	PUNCT
dti-1418	38	33	onset	onset	NOUN
dti-1418	38	34	af	af	PROPN
dti-1418	38	35	53	53	NUM
dti-1418	38	36	%	%	NOUN
dti-1418	38	37	rsd1235	rsd1235	VERB
dti-1418	38	38	:	:	PUNCT
dti-1418	38	39	efficacious	efficacious	ADJ
dti-1418	38	40	and	and	CCONJ
dti-1418	38	41	safe	safe	ADJ
dti-1418	38	42	for	for	ADP
dti-1418	38	43	converting	convert	VERB
dti-1418	38	44	recent	recent	ADJ
dti-1418	38	45	-	-	PUNCT
dti-1418	38	46	onset	onset	NOUN
dti-1418	38	47	af	af	PROPN
dti-1418	38	48	act	act	PROPN
dti-1418	38	49	i23	i23	PROPN
dti-1418	38	50	randomized	randomize	VERB
dti-1418	38	51	,	,	PUNCT
dti-1418	38	52	double	double	ADJ
dti-1418	38	53	-	-	PUNCT
dti-1418	38	54	blind	blind	ADJ
dti-1418	38	55	,	,	PUNCT
dti-1418	38	56	placebocontrolled	placebocontrolle	VERB
dti-1418	38	57	2008	2008	NUM
dti-1418	38	58	336	336	NUM
dti-1418	38	59	pts	pts	ADP
dti-1418	38	60	recent	recent	ADJ
dti-1418	38	61	-	-	PUNCT
dti-1418	38	62	onset	onset	NOUN
dti-1418	38	63	af	af	PROPN
dti-1418	38	64	51.7	51.7	NUM
dti-1418	38	65	%	%	NOUN
dti-1418	38	66	rapid	rapid	ADJ
dti-1418	38	67	conversion	conversion	NOUN
dti-1418	38	68	of	of	ADP
dti-1418	38	69	short	short	ADJ
dti-1418	38	70	-	-	PUNCT
dti-1418	38	71	duration	duration	NOUN
dti-1418	38	72	af	af	PROPN
dti-1418	38	73	act	act	PROPN
dti-1418	38	74	ii24	ii24	PROPN
dti-1418	38	75	randomized	randomize	VERB
dti-1418	38	76	,	,	PUNCT
dti-1418	38	77	double	double	ADJ
dti-1418	38	78	-	-	PUNCT
dti-1418	38	79	blind	blind	ADJ
dti-1418	38	80	,	,	PUNCT
dti-1418	38	81	placebocontrolled	placebocontrolle	VERB
dti-1418	38	82	2009	2009	NUM
dti-1418	38	83	100	100	NUM
dti-1418	38	84	pts	pt	NOUN
dti-1418	38	85	af	af	PROPN
dti-1418	38	86	or	or	CCONJ
dti-1418	38	87	afl	afl	PROPN
dti-1418	38	88	post	post	ADJ
dti-1418	38	89	cardiac	cardiac	ADJ
dti-1418	38	90	surgery	surgery	NOUN
dti-1418	38	91	47	47	NUM
dti-1418	38	92	%	%	NOUN
dti-1418	38	93	safe	safe	ADJ
dti-1418	38	94	and	and	CCONJ
dti-1418	38	95	effective	effective	ADJ
dti-1418	38	96	in	in	ADP
dti-1418	38	97	the	the	DET
dti-1418	38	98	rapid	rapid	ADJ
dti-1418	38	99	conversion	conversion	NOUN
dti-1418	38	100	of	of	ADP
dti-1418	38	101	af	af	PROPN
dti-1418	38	102	post	post	PROPN
dti-1418	38	103	cardiac	cardiac	ADJ
dti-1418	38	104	surgery	surgery	NOUN
dti-1418	38	105	act	act	NOUN
dti-1418	38	106	iii25	iii25	PROPN
dti-1418	38	107	randomized	randomize	VERB
dti-1418	38	108	,	,	PUNCT
dti-1418	38	109	double	double	ADJ
dti-1418	38	110	-	-	PUNCT
dti-1418	38	111	blind	blind	ADJ
dti-1418	38	112	,	,	PUNCT
dti-1418	38	113	placebocontrolled	placebocontrolle	VERB
dti-1418	38	114	2010	2010	NUM
dti-1418	38	115	138	138	NUM
dti-1418	38	116	pts	pt	NOUN
dti-1418	38	117	af	af	PROPN
dti-1418	38	118	or	or	CCONJ
dti-1418	38	119	afl	afl	PROPN
dti-1418	38	120	of	of	ADP
dti-1418	38	121	recent	recent	ADJ
dti-1418	38	122	onset	onset	NOUN
dti-1418	38	123	51.2	51.2	NUM
dti-1418	38	124	%	%	NOUN
dti-1418	38	125	rapid	rapid	ADJ
dti-1418	38	126	and	and	CCONJ
dti-1418	38	127	efficient	efficient	ADJ
dti-1418	38	128	for	for	ADP
dti-1418	38	129	conversion	conversion	NOUN
dti-1418	38	130	of	of	ADP
dti-1418	38	131	short	short	ADJ
dti-1418	38	132	-	-	PUNCT
dti-1418	38	133	duration	duration	NOUN
dti-1418	38	134	af	af	PROPN
dti-1418	38	135	stiell	stiell	NOUN
dti-1418	38	136	et	et	PROPN
dti-1418	38	137	al26	al26	PROPN
dti-1418	38	138	(	(	PUNCT
dti-1418	38	139	act	act	NOUN
dti-1418	38	140	iv	iv	NUM
dti-1418	38	141	)	)	PUNCT
dti-1418	38	142	multicenter	multicenter	NOUN
dti-1418	38	143	,	,	PUNCT
dti-1418	38	144	open	open	ADJ
dti-1418	38	145	-	-	PUNCT
dti-1418	38	146	label	label	NOUN
dti-1418	38	147	study	study	NOUN
dti-1418	38	148	2010	2010	NUM
dti-1418	38	149	236	236	NUM
dti-1418	38	150	pts	pts	ADP
dti-1418	38	151	recent	recent	ADJ
dti-1418	38	152	-	-	PUNCT
dti-1418	38	153	onset	onset	NOUN
dti-1418	38	154	af	af	PROPN
dti-1418	38	155	50.9	50.9	NUM
dti-1418	38	156	%	%	NOUN
dti-1418	38	157	vkl	vkl	NOUN
dti-1418	38	158	rapidly	rapidly	ADV
dti-1418	38	159	converted	convert	VERB
dti-1418	38	160	recent	recent	ADJ
dti-1418	38	161	-	-	PUNCT
dti-1418	38	162	onset	onset	NOUN
dti-1418	38	163	af	af	NOUN
dti-1418	38	164	to	to	ADP
dti-1418	38	165	sr	sr	PROPN
dti-1418	38	166	,	,	PUNCT
dti-1418	38	167	was	be	AUX
dti-1418	38	168	well	well	ADV
dti-1418	38	169	tolerated	tolerate	VERB
dti-1418	38	170	avro28	avro28	NOUN
dti-1418	38	171	randomized	randomize	VERB
dti-1418	38	172	,	,	PUNCT
dti-1418	38	173	double	double	ADJ
dti-1418	38	174	-	-	PUNCT
dti-1418	38	175	blind	blind	ADJ
dti-1418	38	176	,	,	PUNCT
dti-1418	38	177	activecontrolled	activecontrolle	VERB
dti-1418	38	178	with	with	ADP
dti-1418	38	179	amd	amd	PROPN
dti-1418	38	180	2011	2011	NUM
dti-1418	38	181	254	254	NUM
dti-1418	38	182	pts	pts	ADP
dti-1418	38	183	recent	recent	ADJ
dti-1418	38	184	-	-	PUNCT
dti-1418	38	185	onset	onset	NOUN
dti-1418	38	186	af	af	PROPN
dti-1418	38	187	51.7	51.7	NUM
dti-1418	38	188	%	%	NOUN
dti-1418	38	189	vkl	vkl	NOUN
dti-1418	38	190	vs	vs	ADP
dti-1418	38	191	5.2	5.2	NUM
dti-1418	38	192	%	%	NOUN
dti-1418	38	193	amd	amd	PROPN
dti-1418	38	194	vkl	vkl	PROPN
dti-1418	38	195	was	be	AUX
dti-1418	38	196	superior	superior	ADJ
dti-1418	38	197	to	to	PART
dti-1418	38	198	amd	amd	VERB
dti-1418	38	199	for	for	ADP
dti-1418	38	200	acute	acute	ADJ
dti-1418	38	201	conversion	conversion	NOUN
dti-1418	38	202	of	of	ADP
dti-1418	38	203	recent	recent	ADJ
dti-1418	38	204	-	-	PUNCT
dti-1418	38	205	onset	onset	NOUN
dti-1418	38	206	af	af	PROPN
dti-1418	38	207	conde	conde	X
dti-1418	38	208	et	et	PROPN
dti-1418	39	1	al29	al29	PROPN
dti-1418	39	2	prospective	prospective	ADJ
dti-1418	39	3	trial	trial	NOUN
dti-1418	39	4	2013	2013	NUM
dti-1418	39	5	36	36	NUM
dti-1418	39	6	pts	pt	NOUN
dti-1418	39	7	recent	recent	ADJ
dti-1418	39	8	-	-	PUNCT
dti-1418	39	9	onset	onset	NOUN
dti-1418	39	10	af	af	PROPN
dti-1418	39	11	93	93	NUM
dti-1418	39	12	%	%	NOUN
dti-1418	39	13	vkl	vkl	NOUN
dti-1418	39	14	vs	vs	ADP
dti-1418	39	15	78	78	NUM
dti-1418	39	16	%	%	NOUN
dti-1418	39	17	propafenone	propafenone	NOUN
dti-1418	39	18	vkl	vkl	NOUN
dti-1418	39	19	was	be	AUX
dti-1418	39	20	superior	superior	ADJ
dti-1418	39	21	to	to	ADP
dti-1418	39	22	propafenone	propafenone	PROPN
dti-1418	39	23	simon	simon	PROPN
dti-1418	39	24	et	et	PROPN
dti-1418	39	25	al30	al30	PROPN
dti-1418	39	26	randomized	randomize	VERB
dti-1418	39	27	controlled	control	VERB
dti-1418	39	28	trial	trial	NOUN
dti-1418	39	29	2017	2017	NUM
dti-1418	39	30	100	100	NUM
dti-1418	39	31	pts	pts	ADP
dti-1418	39	32	recent	recent	ADJ
dti-1418	39	33	-	-	PUNCT
dti-1418	39	34	onset	onset	NOUN
dti-1418	39	35	af	af	PROPN
dti-1418	39	36	69	69	NUM
dti-1418	39	37	%	%	NOUN
dti-1418	39	38	vkl	vkl	NOUN
dti-1418	39	39	vs	vs	ADP
dti-1418	39	40	43	43	NUM
dti-1418	39	41	%	%	NOUN
dti-1418	39	42	ibutilide	ibutilide	NOUN
dti-1418	39	43	vkl	vkl	NOUN
dti-1418	39	44	was	be	AUX
dti-1418	39	45	superior	superior	ADJ
dti-1418	39	46	to	to	PART
dti-1418	39	47	ibutilide	ibutilide	VERB
dti-1418	39	48	carbajosa	carbajosa	PROPN
dti-1418	39	49	dalmau	dalmau	PROPN
dti-1418	39	50	et	et	NOUN
dti-1418	39	51	al31	al31	PROPN
dti-1418	39	52	prospective	prospective	ADJ
dti-1418	39	53	multicenter	multicenter	NOUN
dti-1418	39	54	2017	2017	NUM
dti-1418	39	55	165	165	NUM
dti-1418	39	56	pts	pt	NOUN
dti-1418	39	57	recent	recent	ADJ
dti-1418	39	58	-	-	PUNCT
dti-1418	39	59	onset	onset	NOUN
dti-1418	39	60	af	af	PROPN
dti-1418	39	61	77.6	77.6	NUM
dti-1418	39	62	%	%	NOUN
dti-1418	39	63	vkl	vkl	NOUN
dti-1418	39	64	is	be	AUX
dti-1418	39	65	effective	effective	ADJ
dti-1418	39	66	and	and	CCONJ
dti-1418	39	67	safe	safe	ADJ
dti-1418	39	68	for	for	ADP
dti-1418	39	69	restoring	restore	VERB
dti-1418	39	70	sr	sr	PROPN
dti-1418	39	71	in	in	ADP
dti-1418	39	72	the	the	DET
dti-1418	39	73	emergency	emergency	NOUN
dti-1418	39	74	department	department	NOUN
dti-1418	39	75	akel	akel	NOUN
dti-1418	39	76	and	and	CCONJ
dti-1418	39	77	lafferty32	lafferty32	VERB
dti-1418	39	78	meta	meta	ADJ
dti-1418	39	79	-	-	PUNCT
dti-1418	39	80	analysis	analysis	NOUN
dti-1418	39	81	2018	2018	NUM
dti-1418	39	82	1421	1421	NUM
dti-1418	39	83	pts	pts	ADP
dti-1418	39	84	recent	recent	ADJ
dti-1418	39	85	-	-	PUNCT
dti-1418	39	86	onset	onset	NOUN
dti-1418	39	87	af	af	NOUN
dti-1418	39	88	na	na	PROPN
dti-1418	39	89	vkl	vkl	PROPN
dti-1418	39	90	is	be	AUX
dti-1418	39	91	effective	effective	ADJ
dti-1418	39	92	for	for	ADP
dti-1418	39	93	rapid	rapid	ADJ
dti-1418	39	94	conversion	conversion	NOUN
dti-1418	39	95	of	of	ADP
dti-1418	39	96	af	af	PROPN
dti-1418	39	97	pohjantähti	pohjantähti	PROPN
dti-1418	39	98	-	-	PUNCT
dti-1418	39	99	maaroos	maaroo	NOUN
dti-1418	39	100	et	et	NOUN
dti-1418	39	101	al33	al33	PROPN
dti-1418	39	102	monocentric	monocentric	ADJ
dti-1418	39	103	,	,	PUNCT
dti-1418	39	104	retrospective	retrospective	ADJ
dti-1418	39	105	2019	2019	NUM
dti-1418	39	106	200	200	NUM
dti-1418	39	107	pts	pt	NOUN
dti-1418	39	108	recent	recent	ADJ
dti-1418	39	109	-	-	PUNCT
dti-1418	39	110	onset	onset	NOUN
dti-1418	39	111	af	af	PROPN
dti-1418	39	112	67	67	NUM
dti-1418	39	113	%	%	NOUN
dti-1418	39	114	with	with	ADP
dti-1418	39	115	vkl	vkl	NOUN
dti-1418	39	116	vs	vs	ADP
dti-1418	39	117	46	46	NUM
dti-1418	39	118	%	%	NOUN
dti-1418	39	119	flecainide	flecainide	PROPN
dti-1418	39	120	vkl	vkl	PROPN
dti-1418	39	121	was	be	AUX
dti-1418	39	122	more	more	ADV
dti-1418	39	123	effective	effective	ADJ
dti-1418	39	124	and	and	CCONJ
dti-1418	39	125	faster	fast	ADV
dti-1418	39	126	than	than	ADP
dti-1418	39	127	flecainide	flecainide	NOUN
dti-1418	39	128	in	in	ADP
dti-1418	39	129	cardioversion	cardioversion	NOUN
dti-1418	39	130	of	of	ADP
dti-1418	39	131	af	af	PROPN
dti-1418	39	132	abbreviations	abbreviation	NOUN
dti-1418	39	133	:	:	PUNCT
dti-1418	40	1	afl	afl	NOUN
dti-1418	40	2	,	,	PUNCT
dti-1418	40	3	trial	trial	NOUN
dti-1418	40	4	flutter	flutter	NOUN
dti-1418	40	5	;	;	PUNCT
dti-1418	40	6	amd	amd	ADJ
dti-1418	40	7	,	,	PUNCT
dti-1418	40	8	amiodarone	amiodarone	NOUN
dti-1418	40	9	;	;	PUNCT
dti-1418	40	10	na	na	NOUN
dti-1418	40	11	,	,	PUNCT
dti-1418	40	12	non	non	X
dti-1418	40	13	available	available	ADJ
dti-1418	40	14	;	;	PUNCT
dti-1418	40	15	pts	pt	NOUN
dti-1418	40	16	,	,	PUNCT
dti-1418	40	17	patients	patient	NOUN
dti-1418	40	18	;	;	PUNCT
dti-1418	40	19	sr	sr	PROPN
dti-1418	40	20	,	,	PUNCT
dti-1418	40	21	sinus	sinus	NOUN
dti-1418	40	22	rhythm	rhythm	NOUN
dti-1418	40	23	;	;	PUNCT
dti-1418	40	24	vkl	vkl	PROPN
dti-1418	40	25	,	,	PUNCT
dti-1418	40	26	vernakalant	vernakalant	PROPN
dti-1418	40	27	.	.	PUNCT
dti-1418	40	28	figure	figure	NOUN
dti-1418	40	29	1	1	NUM
dti-1418	40	30	.	.	PUNCT
dti-1418	40	31	clinical	clinical	ADJ
dti-1418	40	32	scenario	scenario	NOUN
dti-1418	40	33	and	and	CCONJ
dti-1418	40	34	management	management	NOUN
dti-1418	40	35	strategy	strategy	NOUN
dti-1418	40	36	according	accord	VERB
dti-1418	40	37	to	to	ADP
dti-1418	40	38	each	each	DET
dti-1418	40	39	case	case	NOUN
dti-1418	40	40	.	.	PUNCT
dti-1418	41	1	class	class	NOUN
dti-1418	41	2	and	and	CCONJ
dti-1418	41	3	level	level	NOUN
dti-1418	41	4	of	of	ADP
dti-1418	41	5	evidence	evidence	NOUN
dti-1418	41	6	are	be	AUX
dti-1418	41	7	represented	represent	VERB
dti-1418	41	8	between	between	ADP
dti-1418	41	9	parentheses	parenthesis	NOUN
dti-1418	41	10	.	.	PUNCT
dti-1418	42	1	af	af	PROPN
dti-1418	42	2	indicates	indicate	VERB
dti-1418	42	3	atrial	atrial	ADJ
dti-1418	42	4	fibrillation	fibrillation	NOUN
dti-1418	42	5	.	.	PUNCT
dti-1418	43	1	kossaify	kossaify	VERB
dti-1418	43	2	5	5	NUM
dti-1418	43	3	only	only	ADV
dti-1418	43	4	the	the	DET
dti-1418	43	5	500	500	NUM
dti-1418	43	6	mg	mg	NOUN
dti-1418	43	7	dose	dose	NOUN
dti-1418	43	8	showed	show	VERB
dti-1418	43	9	a	a	DET
dti-1418	43	10	slight	slight	ADJ
dti-1418	43	11	superiority	superiority	NOUN
dti-1418	43	12	in	in	ADP
dti-1418	43	13	preventing	prevent	VERB
dti-1418	43	14	recurrence	recurrence	NOUN
dti-1418	43	15	of	of	ADP
dti-1418	43	16	af	af	PROPN
dti-1418	43	17	at	at	ADP
dti-1418	43	18	3	3	NUM
dti-1418	43	19	months	month	NOUN
dti-1418	43	20	.	.	PUNCT
dti-1418	44	1	nevertheless	nevertheless	ADV
dti-1418	44	2	,	,	PUNCT
dti-1418	44	3	in	in	ADP
dti-1418	44	4	march	march	PROPN
dti-1418	44	5	2012	2012	NUM
dti-1418	44	6	,	,	PUNCT
dti-1418	44	7	cardiome	cardiome	NOUN
dti-1418	44	8	and	and	CCONJ
dti-1418	44	9	merck	merck	PROPN
dti-1418	44	10	announced	announce	VERB
dti-1418	44	11	the	the	DET
dti-1418	44	12	discontinuation	discontinuation	NOUN
dti-1418	44	13	of	of	ADP
dti-1418	44	14	further	further	ADJ
dti-1418	44	15	research	research	NOUN
dti-1418	44	16	on	on	ADP
dti-1418	44	17	oral	oral	ADJ
dti-1418	44	18	vernakalant.38	vernakalant.38	PROPN
dti-1418	44	19	vernakalant	vernakalant	NOUN
dti-1418	44	20	was	be	AUX
dti-1418	44	21	approved	approve	VERB
dti-1418	44	22	in	in	ADP
dti-1418	44	23	2010	2010	NUM
dti-1418	44	24	by	by	ADP
dti-1418	44	25	the	the	DET
dti-1418	44	26	european	european	PROPN
dti-1418	44	27	union	union	PROPN
dti-1418	44	28	for	for	ADP
dti-1418	44	29	cardioversion	cardioversion	NOUN
dti-1418	44	30	of	of	ADP
dti-1418	44	31	af	af	PROPN
dti-1418	44	32	which	which	PRON
dti-1418	44	33	was	be	AUX
dti-1418	44	34	less	less	ADJ
dti-1418	44	35	than	than	ADP
dti-1418	44	36	7	7	NUM
dti-1418	44	37	days	day	NOUN
dti-1418	44	38	in	in	ADP
dti-1418	44	39	duration	duration	NOUN
dti-1418	44	40	,	,	PUNCT
dti-1418	44	41	or	or	CCONJ
dti-1418	44	42	for	for	ADP
dti-1418	44	43	post	post	ADJ
dti-1418	44	44	-	-	ADJ
dti-1418	44	45	operative	operative	ADJ
dti-1418	44	46	af	af	NOUN
dti-1418	44	47	less	less	ADJ
dti-1418	44	48	than	than	ADP
dti-1418	44	49	3	3	NUM
dti-1418	44	50	days	day	NOUN
dti-1418	44	51	in	in	ADP
dti-1418	44	52	duration.9	duration.9	PROPN
dti-1418	44	53	vernakalant	vernakalant	NOUN
dti-1418	44	54	is	be	AUX
dti-1418	44	55	still	still	ADV
dti-1418	44	56	not	not	PART
dti-1418	44	57	approved	approve	VERB
dti-1418	44	58	by	by	ADP
dti-1418	44	59	the	the	DET
dti-1418	44	60	united	united	PROPN
dti-1418	44	61	states	states	PROPN
dti-1418	44	62	food	food	PROPN
dti-1418	44	63	and	and	CCONJ
dti-1418	44	64	drug	drug	NOUN
dti-1418	44	65	administration	administration	NOUN
dti-1418	44	66	,	,	PUNCT
dti-1418	44	67	namely	namely	ADV
dti-1418	44	68	after	after	SCONJ
dti-1418	44	69	the	the	DET
dti-1418	44	70	study	study	NOUN
dti-1418	44	71	“	"	PUNCT
dti-1418	44	72	act	act	VERB
dti-1418	44	73	v	v	NOUN
dti-1418	44	74	”	"	PUNCT
dti-1418	44	75	was	be	AUX
dti-1418	44	76	discontinued	discontinue	VERB
dti-1418	44	77	following	follow	VERB
dti-1418	44	78	the	the	DET
dti-1418	44	79	death	death	NOUN
dti-1418	44	80	of	of	ADP
dti-1418	44	81	a	a	DET
dti-1418	44	82	single	single	ADJ
dti-1418	44	83	patient	patient	NOUN
dti-1418	44	84	,	,	PUNCT
dti-1418	44	85	and	and	CCONJ
dti-1418	44	86	therefore	therefore	ADV
dti-1418	44	87	,	,	PUNCT
dti-1418	44	88	further	further	ADJ
dti-1418	44	89	safety	safety	NOUN
dti-1418	44	90	data	datum	NOUN
dti-1418	44	91	and	and	CCONJ
dti-1418	44	92	protocol	protocol	NOUN
dti-1418	44	93	revision	revision	NOUN
dti-1418	44	94	regarding	regard	VERB
dti-1418	44	95	drug	drug	NOUN
dti-1418	44	96	administration	administration	NOUN
dti-1418	44	97	were	be	AUX
dti-1418	44	98	required	require	VERB
dti-1418	44	99	for	for	ADP
dti-1418	44	100	approval	approval	NOUN
dti-1418	44	101	by	by	ADP
dti-1418	44	102	the	the	DET
dti-1418	44	103	food	food	NOUN
dti-1418	44	104	and	and	CCONJ
dti-1418	44	105	drug	drug	NOUN
dti-1418	44	106	administration.9,38	administration.9,38	PROPN
dti-1418	44	107	opinions	opinion	NOUN
dti-1418	44	108	,	,	PUNCT
dti-1418	44	109	clinical	clinical	ADJ
dti-1418	44	110	implications	implication	NOUN
dti-1418	44	111	a	a	DET
dti-1418	44	112	lot	lot	NOUN
dti-1418	44	113	of	of	ADP
dti-1418	44	114	progress	progress	NOUN
dti-1418	44	115	has	have	AUX
dti-1418	44	116	occurred	occur	VERB
dti-1418	44	117	in	in	ADP
dti-1418	44	118	rhythm	rhythm	NOUN
dti-1418	44	119	control	control	NOUN
dti-1418	44	120	strategies	strategy	NOUN
dti-1418	44	121	for	for	ADP
dti-1418	44	122	af	af	PROPN
dti-1418	44	123	,	,	PUNCT
dti-1418	44	124	especially	especially	ADV
dti-1418	44	125	with	with	ADP
dti-1418	44	126	the	the	DET
dti-1418	44	127	development	development	NOUN
dti-1418	44	128	of	of	ADP
dti-1418	44	129	ablation	ablation	NOUN
dti-1418	44	130	procedures	procedure	NOUN
dti-1418	44	131	;	;	PUNCT
dti-1418	44	132	however	however	ADV
dti-1418	44	133	,	,	PUNCT
dti-1418	44	134	pharmacological	pharmacological	ADJ
dti-1418	44	135	cardioversion	cardioversion	NOUN
dti-1418	44	136	should	should	AUX
dti-1418	44	137	be	be	AUX
dti-1418	44	138	preserved	preserve	VERB
dti-1418	44	139	as	as	ADP
dti-1418	44	140	first	first	ADV
dti-1418	44	141	and	and	CCONJ
dti-1418	44	142	integrated	integrated	ADJ
dti-1418	44	143	approach	approach	NOUN
dti-1418	44	144	for	for	ADP
dti-1418	44	145	the	the	DET
dti-1418	44	146	management	management	NOUN
dti-1418	44	147	of	of	ADP
dti-1418	44	148	af	af	PROPN
dti-1418	44	149	.	.	PROPN
dti-1418	44	150	vernakalant	vernakalant	NOUN
dti-1418	44	151	showed	show	VERB
dti-1418	44	152	a	a	DET
dti-1418	44	153	superior	superior	ADJ
dti-1418	44	154	efficacy	efficacy	NOUN
dti-1418	44	155	to	to	PART
dti-1418	44	156	amiodarone	amiodarone	VERB
dti-1418	44	157	and	and	CCONJ
dti-1418	44	158	to	to	ADP
dti-1418	44	159	other	other	ADJ
dti-1418	44	160	aad	aad	INTJ
dti-1418	44	161	for	for	ADP
dti-1418	44	162	rapid	rapid	ADJ
dti-1418	44	163	conversion	conversion	NOUN
dti-1418	44	164	of	of	ADP
dti-1418	44	165	recent	recent	ADJ
dti-1418	44	166	-	-	PUNCT
dti-1418	44	167	onset	onset	NOUN
dti-1418	44	168	af;29,33,36,37,42	af;29,33,36,37,42	NOUN
dti-1418	44	169	although	although	SCONJ
dti-1418	44	170	it	it	PRON
dti-1418	44	171	can	can	AUX
dti-1418	44	172	be	be	AUX
dti-1418	44	173	given	give	VERB
dti-1418	44	174	in	in	ADP
dti-1418	44	175	patients	patient	NOUN
dti-1418	44	176	with	with	ADP
dti-1418	44	177	mild	mild	ADJ
dti-1418	44	178	to	to	AUX
dti-1418	44	179	moderate	moderate	ADJ
dti-1418	44	180	cardiovascular	cardiovascular	ADJ
dti-1418	44	181	conditions	condition	NOUN
dti-1418	44	182	,	,	PUNCT
dti-1418	44	183	the	the	DET
dti-1418	44	184	absence	absence	NOUN
dti-1418	44	185	of	of	ADP
dti-1418	44	186	structural	structural	ADJ
dti-1418	44	187	heart	heart	NOUN
dti-1418	44	188	disease	disease	NOUN
dti-1418	44	189	is	be	AUX
dti-1418	44	190	associated	associate	VERB
dti-1418	44	191	with	with	ADP
dti-1418	44	192	greater	great	ADJ
dti-1418	44	193	conversion	conversion	NOUN
dti-1418	44	194	rate	rate	NOUN
dti-1418	44	195	to	to	ADP
dti-1418	44	196	sinus	sinus	NOUN
dti-1418	44	197	rhythm.43	rhythm.43	NOUN
dti-1418	44	198	vernakalant	vernakalant	NOUN
dti-1418	44	199	is	be	AUX
dti-1418	44	200	a	a	DET
dti-1418	44	201	relatively	relatively	ADV
dti-1418	44	202	safe	safe	ADJ
dti-1418	44	203	drug	drug	NOUN
dti-1418	44	204	and	and	CCONJ
dti-1418	45	1	manolis	manolis	PROPN
dti-1418	45	2	et	et	NOUN
dti-1418	45	3	 	 	SPACE
dti-1418	45	4	al44	al44	PROPN
dti-1418	45	5	reported	report	VERB
dti-1418	45	6	successful	successful	ADJ
dti-1418	45	7	utilization	utilization	NOUN
dti-1418	45	8	of	of	ADP
dti-1418	45	9	intravenous	intravenous	ADJ
dti-1418	45	10	vernakalant	vernakalant	NOUN
dti-1418	45	11	for	for	ADP
dti-1418	45	12	af	af	PROPN
dti-1418	45	13	conversion	conversion	NOUN
dti-1418	45	14	in	in	ADP
dti-1418	45	15	the	the	DET
dti-1418	45	16	regular	regular	ADJ
dti-1418	45	17	ward	ward	NOUN
dti-1418	45	18	under	under	ADP
dti-1418	45	19	only	only	ADJ
dti-1418	45	20	bedside	bedside	NOUN
dti-1418	45	21	monitoring	monitoring	NOUN
dti-1418	45	22	.	.	PUNCT
dti-1418	46	1	anticoagulation	anticoagulation	NOUN
dti-1418	46	2	should	should	AUX
dti-1418	46	3	be	be	AUX
dti-1418	46	4	started	start	VERB
dti-1418	46	5	promptly	promptly	ADV
dti-1418	46	6	in	in	ADP
dti-1418	46	7	all	all	DET
dti-1418	46	8	patients	patient	NOUN
dti-1418	46	9	presenting	present	VERB
dti-1418	46	10	with	with	ADP
dti-1418	46	11	af	af	PROPN
dti-1418	46	12	,	,	PUNCT
dti-1418	46	13	not	not	PART
dti-1418	46	14	only	only	ADV
dti-1418	46	15	in	in	ADP
dti-1418	46	16	those	those	PRON
dti-1418	46	17	presenting	present	VERB
dti-1418	46	18	with	with	ADP
dti-1418	46	19	af	af	PROPN
dti-1418	46	20	lasting	last	VERB
dti-1418	46	21	since	since	SCONJ
dti-1418	46	22	more	more	ADJ
dti-1418	46	23	than	than	ADP
dti-1418	46	24	48	48	NUM
dti-1418	46	25	h.45–48	h.45–48	NOUN
dti-1418	46	26	moreover	moreover	ADV
dti-1418	46	27	,	,	PUNCT
dti-1418	46	28	cardioversion	cardioversion	NOUN
dti-1418	46	29	should	should	AUX
dti-1418	46	30	not	not	PART
dti-1418	46	31	be	be	AUX
dti-1418	46	32	attempted	attempt	VERB
dti-1418	46	33	in	in	ADP
dti-1418	46	34	those	those	PRON
dti-1418	46	35	presenting	present	VERB
dti-1418	46	36	with	with	ADP
dti-1418	46	37	af	af	PROPN
dti-1418	46	38	lasting	last	VERB
dti-1418	46	39	since	since	SCONJ
dti-1418	46	40	more	more	ADJ
dti-1418	46	41	than	than	ADP
dti-1418	46	42	48	48	NUM
dti-1418	46	43	h	h	NOUN
dti-1418	46	44	before	before	SCONJ
dti-1418	46	45	effective	effective	ADJ
dti-1418	46	46	anticoagulation	anticoagulation	NOUN
dti-1418	46	47	has	have	AUX
dti-1418	46	48	been	be	AUX
dti-1418	46	49	established	establish	VERB
dti-1418	46	50	for	for	ADP
dti-1418	46	51	at	at	ADV
dti-1418	46	52	least	least	ADV
dti-1418	46	53	3	3	NUM
dti-1418	46	54	weeks	week	NOUN
dti-1418	46	55	(	(	PUNCT
dti-1418	46	56	except	except	SCONJ
dti-1418	46	57	for	for	ADP
dti-1418	46	58	patients	patient	NOUN
dti-1418	46	59	with	with	ADP
dti-1418	46	60	hemodynamic	hemodynamic	ADJ
dti-1418	46	61	compromise	compromise	NOUN
dti-1418	46	62	requiring	require	VERB
dti-1418	46	63	immediate	immediate	ADJ
dti-1418	46	64	cardioversion	cardioversion	NOUN
dti-1418	46	65	)	)	PUNCT
dti-1418	46	66	.	.	PUNCT
dti-1418	47	1	however	however	ADV
dti-1418	47	2	,	,	PUNCT
dti-1418	47	3	if	if	SCONJ
dti-1418	47	4	cardioversion	cardioversion	NOUN
dti-1418	47	5	needs	need	VERB
dti-1418	47	6	to	to	PART
dti-1418	47	7	be	be	AUX
dti-1418	47	8	performed	perform	VERB
dti-1418	47	9	sooner	soon	ADV
dti-1418	47	10	,	,	PUNCT
dti-1418	47	11	then	then	ADV
dti-1418	47	12	transesophageal	transesophageal	ADJ
dti-1418	47	13	echo	echo	NOUN
dti-1418	47	14	guidance	guidance	NOUN
dti-1418	47	15	is	be	AUX
dti-1418	47	16	recommended.49	recommended.49	ADV
dti-1418	47	17	clinical	clinical	ADJ
dti-1418	47	18	risk	risk	NOUN
dti-1418	47	19	scores	score	NOUN
dti-1418	47	20	for	for	ADP
dti-1418	47	21	stroke	stroke	NOUN
dti-1418	47	22	and	and	CCONJ
dti-1418	47	23	systemic	systemic	ADJ
dti-1418	47	24	embolism	embolism	NOUN
dti-1418	47	25	including	include	VERB
dti-1418	47	26	the	the	DET
dti-1418	47	27	cha2ds2	cha2ds2	PROPN
dti-1418	47	28	-	-	PUNCT
dti-1418	47	29	vasc	vasc	ADJ
dti-1418	47	30	score	score	NOUN
dti-1418	47	31	should	should	AUX
dti-1418	47	32	be	be	AUX
dti-1418	47	33	implemented	implement	VERB
dti-1418	47	34	more	more	ADV
dti-1418	47	35	frequently	frequently	ADV
dti-1418	47	36	in	in	ADP
dti-1418	47	37	real	real	ADJ
dti-1418	47	38	practice.3,47	practice.3,47	PROPN
dti-1418	47	39	in	in	ADP
dti-1418	47	40	this	this	DET
dti-1418	47	41	regard	regard	NOUN
dti-1418	47	42	,	,	PUNCT
dti-1418	47	43	a	a	DET
dti-1418	47	44	patient	patient	NOUN
dti-1418	47	45	presenting	presenting	NOUN
dti-1418	47	46	to	to	ADP
dti-1418	47	47	the	the	DET
dti-1418	47	48	emergency	emergency	NOUN
dti-1418	47	49	department	department	NOUN
dti-1418	47	50	needs	need	VERB
dti-1418	47	51	a	a	DET
dti-1418	47	52	minimum	minimum	NOUN
dti-1418	47	53	workup	workup	NOUN
dti-1418	47	54	to	to	PART
dti-1418	47	55	ensure	ensure	VERB
dti-1418	47	56	that	that	SCONJ
dti-1418	47	57	it	it	PRON
dti-1418	47	58	is	be	AUX
dti-1418	47	59	a	a	DET
dti-1418	47	60	recent	recent	ADJ
dti-1418	47	61	-	-	PUNCT
dti-1418	47	62	onset	onset	NOUN
dti-1418	47	63	af	af	NOUN
dti-1418	47	64	,	,	PUNCT
dti-1418	47	65	and	and	CCONJ
dti-1418	47	66	this	this	PRON
dti-1418	47	67	is	be	AUX
dti-1418	47	68	required	require	VERB
dti-1418	47	69	for	for	ADP
dti-1418	47	70	evaluating	evaluate	VERB
dti-1418	47	71	potential	potential	ADJ
dti-1418	47	72	underlying	underlie	VERB
dti-1418	47	73	cardiopathy	cardiopathy	ADJ
dti-1418	47	74	,	,	PUNCT
dti-1418	47	75	and	and	CCONJ
dti-1418	47	76	for	for	ADP
dti-1418	47	77	assessment	assessment	NOUN
dti-1418	47	78	of	of	ADP
dti-1418	47	79	the	the	DET
dti-1418	47	80	relevance	relevance	NOUN
dti-1418	47	81	of	of	ADP
dti-1418	47	82	vernakalant	vernakalant	NOUN
dti-1418	47	83	use	use	NOUN
dti-1418	47	84	according	accord	VERB
dti-1418	47	85	to	to	ADP
dti-1418	47	86	the	the	DET
dti-1418	47	87	estimated	estimate	VERB
dti-1418	47	88	af	af	PROPN
dti-1418	47	89	duration	duration	NOUN
dti-1418	47	90	.	.	PUNCT
dti-1418	48	1	the	the	DET
dti-1418	48	2	new	new	ADJ
dti-1418	48	3	af	af	PROPN
dti-1418	48	4	guidelines3	guidelines3	PROPN
dti-1418	48	5	classify	classify	VERB
dti-1418	48	6	a	a	DET
dti-1418	48	7	first	first	ADJ
dti-1418	48	8	time	time	NOUN
dti-1418	48	9	diagnosed	diagnose	VERB
dti-1418	48	10	af	af	PRON
dti-1418	48	11	as	as	ADP
dti-1418	48	12	“	"	PUNCT
dti-1418	48	13	first	first	ADV
dti-1418	48	14	diagnosed	diagnose	VERB
dti-1418	48	15	af	af	PROPN
dti-1418	48	16	,	,	PUNCT
dti-1418	48	17	”	"	PUNCT
dti-1418	48	18	which	which	PRON
dti-1418	48	19	is	be	AUX
dti-1418	48	20	defined	define	VERB
dti-1418	48	21	as	as	ADP
dti-1418	48	22	af	af	PROPN
dti-1418	48	23	that	that	PRON
dti-1418	48	24	has	have	AUX
dti-1418	48	25	not	not	PART
dti-1418	48	26	been	be	AUX
dti-1418	48	27	diagnosed	diagnose	VERB
dti-1418	48	28	before	before	ADV
dti-1418	48	29	,	,	PUNCT
dti-1418	48	30	irrespective	irrespective	ADV
dti-1418	48	31	of	of	ADP
dti-1418	48	32	its	its	PRON
dti-1418	48	33	duration	duration	NOUN
dti-1418	48	34	or	or	CCONJ
dti-1418	48	35	severity	severity	NOUN
dti-1418	48	36	.	.	PUNCT
dti-1418	49	1	accordingly	accordingly	ADV
dti-1418	49	2	,	,	PUNCT
dti-1418	49	3	patients	patient	NOUN
dti-1418	49	4	presenting	present	VERB
dti-1418	49	5	to	to	ADP
dti-1418	49	6	emergency	emergency	NOUN
dti-1418	49	7	room	room	NOUN
dti-1418	49	8	for	for	ADP
dti-1418	49	9	a	a	DET
dti-1418	49	10	first	first	ADJ
dti-1418	49	11	episode	episode	NOUN
dti-1418	49	12	of	of	ADP
dti-1418	49	13	af	af	PROPN
dti-1418	49	14	are	be	AUX
dti-1418	49	15	classified	classify	VERB
dti-1418	49	16	as	as	ADP
dti-1418	49	17	“	"	PUNCT
dti-1418	49	18	first	first	ADV
dti-1418	49	19	diagnosed	diagnose	VERB
dti-1418	49	20	af	af	PROPN
dti-1418	49	21	,	,	PUNCT
dti-1418	49	22	”	"	PUNCT
dti-1418	49	23	and	and	CCONJ
dti-1418	49	24	this	this	PRON
dti-1418	49	25	af	af	NOUN
dti-1418	49	26	may	may	AUX
dti-1418	49	27	be	be	AUX
dti-1418	49	28	otherwise	otherwise	ADV
dti-1418	49	29	paroxysmal	paroxysmal	ADJ
dti-1418	49	30	or	or	CCONJ
dti-1418	49	31	even	even	ADV
dti-1418	49	32	persistent	persistent	ADJ
dti-1418	49	33	.	.	PUNCT
dti-1418	50	1	in	in	ADP
dti-1418	50	2	other	other	ADJ
dti-1418	50	3	terms	term	NOUN
dti-1418	50	4	,	,	PUNCT
dti-1418	50	5	a	a	DET
dti-1418	50	6	patient	patient	NOUN
dti-1418	50	7	may	may	AUX
dti-1418	50	8	present	present	VERB
dti-1418	50	9	to	to	ADP
dti-1418	50	10	the	the	DET
dti-1418	50	11	emergency	emergency	NOUN
dti-1418	50	12	department	department	NOUN
dti-1418	50	13	with	with	ADP
dti-1418	50	14	af	af	PROPN
dti-1418	50	15	only	only	ADV
dti-1418	50	16	when	when	SCONJ
dti-1418	50	17	symptoms	symptom	NOUN
dti-1418	50	18	become	become	VERB
dti-1418	50	19	severe	severe	ADJ
dti-1418	50	20	;	;	PUNCT
dti-1418	50	21	however	however	ADV
dti-1418	50	22	,	,	PUNCT
dti-1418	50	23	he	he	PRON
dti-1418	50	24	may	may	AUX
dti-1418	50	25	be	be	AUX
dti-1418	50	26	asymptomatic	asymptomatic	ADJ
dti-1418	50	27	or	or	CCONJ
dti-1418	50	28	pauci	pauci	NOUN
dti-1418	50	29	-	-	PUNCT
dti-1418	50	30	symptomatic	symptomatic	ADJ
dti-1418	50	31	with	with	ADP
dti-1418	50	32	an	an	DET
dti-1418	50	33	af	af	AUX
dti-1418	50	34	lasting	last	VERB
dti-1418	50	35	since	since	SCONJ
dti-1418	50	36	days	day	NOUN
dti-1418	50	37	,	,	PUNCT
dti-1418	50	38	weeks	week	NOUN
dti-1418	50	39	,	,	PUNCT
dti-1418	50	40	or	or	CCONJ
dti-1418	50	41	months	month	NOUN
dti-1418	50	42	,	,	PUNCT
dti-1418	50	43	especially	especially	ADV
dti-1418	50	44	if	if	SCONJ
dti-1418	50	45	the	the	DET
dti-1418	50	46	af	af	NOUN
dti-1418	50	47	is	be	AUX
dti-1418	50	48	intermittent	intermittent	ADJ
dti-1418	50	49	.	.	PUNCT
dti-1418	51	1	before	before	ADP
dti-1418	51	2	using	use	VERB
dti-1418	51	3	vernakalant	vernakalant	NOUN
dti-1418	51	4	,	,	PUNCT
dti-1418	51	5	patients	patient	NOUN
dti-1418	51	6	should	should	AUX
dti-1418	51	7	be	be	AUX
dti-1418	51	8	adequately	adequately	ADV
dti-1418	51	9	hydrated	hydrate	VERB
dti-1418	51	10	;	;	PUNCT
dti-1418	51	11	the	the	DET
dti-1418	51	12	current	current	ADJ
dti-1418	51	13	dosage	dosage	NOUN
dti-1418	51	14	recommendation	recommendation	NOUN
dti-1418	51	15	consists	consist	VERB
dti-1418	51	16	of	of	ADP
dti-1418	51	17	a	a	DET
dti-1418	51	18	first	first	ADJ
dti-1418	51	19	infusion	infusion	NOUN
dti-1418	51	20	3	3	NUM
dti-1418	51	21	mg	mg	PROPN
dti-1418	51	22	/	/	SYM
dti-1418	51	23	kg	kg	NOUN
dti-1418	51	24	over	over	ADP
dti-1418	51	25	10	10	NUM
dti-1418	51	26	minutes	minute	NOUN
dti-1418	51	27	,	,	PUNCT
dti-1418	51	28	then	then	ADV
dti-1418	51	29	a	a	DET
dti-1418	51	30	monitoring	monitoring	NOUN
dti-1418	51	31	period	period	NOUN
dti-1418	51	32	of	of	ADP
dti-1418	51	33	15	15	NUM
dti-1418	51	34	minutes	minute	NOUN
dti-1418	51	35	,	,	PUNCT
dti-1418	51	36	and	and	CCONJ
dti-1418	51	37	if	if	SCONJ
dti-1418	51	38	af	af	PROPN
dti-1418	51	39	persists	persist	VERB
dti-1418	51	40	,	,	PUNCT
dti-1418	51	41	a	a	DET
dti-1418	51	42	second	second	ADJ
dti-1418	51	43	infusion	infusion	NOUN
dti-1418	51	44	of	of	ADP
dti-1418	51	45	2	2	NUM
dti-1418	51	46	mg	mg	NOUN
dti-1418	51	47	/	/	SYM
dti-1418	51	48	kg	kg	NOUN
dti-1418	51	49	over	over	ADP
dti-1418	51	50	10	10	NUM
dti-1418	51	51	minutes	minute	NOUN
dti-1418	51	52	with	with	ADP
dti-1418	51	53	a	a	DET
dti-1418	51	54	second	second	ADJ
dti-1418	51	55	monitoring	monitoring	NOUN
dti-1418	51	56	period	period	NOUN
dti-1418	51	57	of	of	ADP
dti-1418	51	58	15	15	NUM
dti-1418	51	59	minutes	minute	NOUN
dti-1418	51	60	,	,	PUNCT
dti-1418	51	61	the	the	DET
dti-1418	51	62	maximal	maximal	ADJ
dti-1418	51	63	dose	dose	NOUN
dti-1418	51	64	over	over	ADP
dti-1418	51	65	24	24	NUM
dti-1418	51	66	hours	hour	NOUN
dti-1418	51	67	being	be	AUX
dti-1418	51	68	5	5	NUM
dti-1418	51	69	mg	mg	PROPN
dti-1418	51	70	/	/	SYM
dti-1418	51	71	kg3	kg3	PROPN
dti-1418	51	72	.	.	PUNCT
dti-1418	52	1	interestingly	interestingly	ADV
dti-1418	52	2	,	,	PUNCT
dti-1418	52	3	electrical	electrical	ADJ
dti-1418	52	4	cardioversion	cardioversion	NOUN
dti-1418	52	5	is	be	AUX
dti-1418	52	6	still	still	ADV
dti-1418	52	7	feasible	feasible	ADJ
dti-1418	52	8	after	after	ADP
dti-1418	52	9	administration	administration	NOUN
dti-1418	52	10	of	of	ADP
dti-1418	52	11	vernakalant	vernakalant	NOUN
dti-1418	52	12	,	,	PUNCT
dti-1418	52	13	and	and	CCONJ
dti-1418	52	14	it	it	PRON
dti-1418	52	15	enhances	enhance	VERB
dti-1418	52	16	restoration	restoration	NOUN
dti-1418	52	17	of	of	ADP
dti-1418	52	18	sinus	sinus	NOUN
dti-1418	52	19	rhythm	rhythm	NOUN
dti-1418	52	20	as	as	ADP
dti-1418	52	21	integrated	integrate	VERB
dti-1418	52	22	approach	approach	NOUN
dti-1418	52	23	for	for	ADP
dti-1418	52	24	af	af	NOUN
dti-1418	52	25	;	;	PUNCT
dti-1418	52	26	however	however	ADV
dti-1418	52	27	,	,	PUNCT
dti-1418	52	28	its	its	PRON
dti-1418	52	29	use	use	NOUN
dti-1418	52	30	is	be	AUX
dti-1418	52	31	recommended	recommend	VERB
dti-1418	52	32	only	only	ADV
dti-1418	52	33	120	120	NUM
dti-1418	52	34	min	min	NOUN
dti-1418	52	35	after	after	ADP
dti-1418	52	36	vernakalant	vernakalant	NOUN
dti-1418	52	37	administration	administration	NOUN
dti-1418	52	38	;	;	PUNCT
dti-1418	52	39	therefore	therefore	ADV
dti-1418	52	40	,	,	PUNCT
dti-1418	52	41	vernakalant	vernakalant	NOUN
dti-1418	52	42	may	may	AUX
dti-1418	52	43	be	be	AUX
dti-1418	52	44	considered	consider	VERB
dti-1418	52	45	as	as	ADP
dti-1418	52	46	a	a	DET
dti-1418	52	47	useful	useful	ADJ
dti-1418	52	48	agent	agent	NOUN
dti-1418	52	49	for	for	ADP
dti-1418	52	50	facilitated	facilitate	VERB
dti-1418	52	51	electrical	electrical	ADJ
dti-1418	52	52	cardioversion	cardioversion	NOUN
dti-1418	52	53	in	in	ADP
dti-1418	52	54	resistant	resistant	ADJ
dti-1418	52	55	and	and	CCONJ
dti-1418	52	56	recent	recent	ADJ
dti-1418	52	57	-	-	PUNCT
dti-1418	52	58	onset	onset	VERB
dti-1418	52	59	af;50	af;50	NOUN
dti-1418	52	60	figure	figure	NOUN
dti-1418	52	61	2	2	NUM
dti-1418	52	62	illustrates	illustrate	VERB
dti-1418	52	63	this	this	DET
dti-1418	52	64	scenario	scenario	NOUN
dti-1418	52	65	.	.	PUNCT
dti-1418	53	1	of	of	ADP
dti-1418	53	2	note	note	NOUN
dti-1418	53	3	,	,	PUNCT
dti-1418	53	4	vernakalant	vernakalant	NOUN
dti-1418	53	5	is	be	AUX
dti-1418	53	6	indicated	indicate	VERB
dti-1418	53	7	for	for	ADP
dti-1418	53	8	recent	recent	ADJ
dti-1418	53	9	-	-	PUNCT
dti-1418	53	10	onset	onset	NOUN
dti-1418	53	11	af	af	NOUN
dti-1418	53	12	;	;	PUNCT
dti-1418	53	13	nonetheless	nonetheless	ADV
dti-1418	53	14	,	,	PUNCT
dti-1418	53	15	the	the	DET
dti-1418	53	16	indication	indication	NOUN
dti-1418	53	17	is	be	AUX
dti-1418	53	18	not	not	PART
dti-1418	53	19	extended	extend	VERB
dti-1418	53	20	to	to	ADP
dti-1418	53	21	atrial	atrial	ADJ
dti-1418	53	22	flutter.3	flutter.3	NOUN
dti-1418	53	23	carbajosa	carbajosa	PROPN
dti-1418	53	24	dalmau	dalmau	PROPN
dti-1418	54	1	et	et	NOUN
dti-1418	54	2	 	 	SPACE
dti-1418	54	3	al31	al31	PROPN
dti-1418	54	4	showed	show	VERB
dti-1418	54	5	that	that	SCONJ
dti-1418	54	6	af	af	PROPN
dti-1418	54	7	duration	duration	NOUN
dti-1418	54	8	of	of	ADP
dti-1418	54	9	less	less	ADJ
dti-1418	54	10	than	than	ADP
dti-1418	54	11	12	12	NUM
dti-1418	54	12	h	h	NOUN
dti-1418	54	13	was	be	AUX
dti-1418	54	14	significantly	significantly	ADV
dti-1418	54	15	associated	associate	VERB
dti-1418	54	16	with	with	ADP
dti-1418	54	17	greater	great	ADJ
dti-1418	54	18	effectiveness	effectiveness	NOUN
dti-1418	54	19	in	in	ADP
dti-1418	54	20	the	the	DET
dti-1418	54	21	hospital	hospital	NOUN
dti-1418	54	22	emergency	emergency	NOUN
dti-1418	54	23	department	department	NOUN
dti-1418	54	24	.	.	PUNCT
dti-1418	55	1	finally	finally	ADV
dti-1418	55	2	,	,	PUNCT
dti-1418	55	3	cost	cost	NOUN
dti-1418	55	4	-	-	PUNCT
dti-1418	55	5	effectiveness	effectiveness	NOUN
dti-1418	55	6	studies	study	NOUN
dti-1418	55	7	of	of	ADP
dti-1418	55	8	vernakalant	vernakalant	NOUN
dti-1418	55	9	applied	apply	VERB
dti-1418	55	10	in	in	ADP
dti-1418	55	11	“	"	PUNCT
dti-1418	55	12	real	real	ADJ
dti-1418	55	13	world	world	NOUN
dti-1418	55	14	”	"	PUNCT
dti-1418	55	15	remain	remain	VERB
dti-1418	55	16	to	to	PART
dti-1418	55	17	be	be	AUX
dti-1418	55	18	figure	figure	NOUN
dti-1418	55	19	2	2	NUM
dti-1418	55	20	.	.	PUNCT
dti-1418	55	21	image	image	NOUN
dti-1418	55	22	showing	show	VERB
dti-1418	55	23	the	the	DET
dti-1418	55	24	infusion	infusion	NOUN
dti-1418	55	25	scenario	scenario	NOUN
dti-1418	55	26	with	with	ADP
dti-1418	55	27	dosage	dosage	NOUN
dti-1418	55	28	and	and	CCONJ
dti-1418	55	29	monitoring	monitoring	NOUN
dti-1418	55	30	time	time	NOUN
dti-1418	55	31	,	,	PUNCT
dti-1418	55	32	ending	end	VERB
dti-1418	55	33	with	with	ADP
dti-1418	55	34	electrical	electrical	ADJ
dti-1418	55	35	cardioversion	cardioversion	NOUN
dti-1418	55	36	if	if	SCONJ
dti-1418	55	37	af	af	PROPN
dti-1418	55	38	persists	persist	VERB
dti-1418	55	39	.	.	PUNCT
dti-1418	56	1	af	af	PROPN
dti-1418	56	2	indicates	indicate	VERB
dti-1418	56	3	atrial	atrial	ADJ
dti-1418	56	4	fibrillation	fibrillation	NOUN
dti-1418	56	5	.	.	PUNCT
dti-1418	57	1	6	6	NUM
dti-1418	57	2	drug	drug	NOUN
dti-1418	57	3	target	target	NOUN
dti-1418	57	4	insights	insight	NOUN
dti-1418	57	5	evaluated	evaluate	VERB
dti-1418	57	6	;	;	PUNCT
dti-1418	57	7	moreover	moreover	ADV
dti-1418	57	8	,	,	PUNCT
dti-1418	57	9	caution	caution	NOUN
dti-1418	57	10	about	about	ADP
dti-1418	57	11	safety	safety	NOUN
dti-1418	57	12	and	and	CCONJ
dti-1418	57	13	use	use	NOUN
dti-1418	57	14	of	of	ADP
dti-1418	57	15	vernakalant	vernakalant	NOUN
dti-1418	57	16	within	within	ADP
dti-1418	57	17	specific	specific	ADJ
dti-1418	57	18	patients	patient	NOUN
dti-1418	57	19	’	'	PUNCT
dti-1418	57	20	subgroups	subgroup	NOUN
dti-1418	57	21	must	must	AUX
dti-1418	57	22	be	be	AUX
dti-1418	57	23	considered.32,51	considered.32,51	VERB
dti-1418	57	24	conclusions	conclusion	NOUN
dti-1418	57	25	af	af	PROPN
dti-1418	57	26	is	be	AUX
dti-1418	57	27	the	the	DET
dti-1418	57	28	most	most	ADV
dti-1418	57	29	common	common	ADJ
dti-1418	57	30	arrhythmia	arrhythmia	NOUN
dti-1418	57	31	in	in	ADP
dti-1418	57	32	patients	patient	NOUN
dti-1418	57	33	admitted	admit	VERB
dti-1418	57	34	to	to	ADP
dti-1418	57	35	emergency	emergency	NOUN
dti-1418	57	36	departments	department	NOUN
dti-1418	57	37	or	or	CCONJ
dti-1418	57	38	hospitalized	hospitalize	VERB
dti-1418	57	39	in	in	ADP
dti-1418	57	40	intensive	intensive	ADJ
dti-1418	57	41	care	care	NOUN
dti-1418	57	42	units	unit	NOUN
dti-1418	57	43	;	;	PUNCT
dti-1418	57	44	also	also	ADV
dti-1418	57	45	it	it	PRON
dti-1418	57	46	is	be	AUX
dti-1418	57	47	associated	associate	VERB
dti-1418	57	48	with	with	ADP
dti-1418	57	49	increased	increase	VERB
dti-1418	57	50	morbidity	morbidity	NOUN
dti-1418	57	51	and	and	CCONJ
dti-1418	57	52	mortality	mortality	NOUN
dti-1418	57	53	.	.	PUNCT
dti-1418	58	1	the	the	DET
dti-1418	58	2	increasing	increase	VERB
dti-1418	58	3	incidence	incidence	NOUN
dti-1418	58	4	of	of	ADP
dti-1418	58	5	af	af	PROPN
dti-1418	58	6	has	have	AUX
dti-1418	58	7	prompted	prompt	VERB
dti-1418	58	8	researches	research	NOUN
dti-1418	58	9	to	to	PART
dti-1418	58	10	find	find	VERB
dti-1418	58	11	new	new	ADJ
dti-1418	58	12	therapeutic	therapeutic	ADJ
dti-1418	58	13	alternatives	alternative	NOUN
dti-1418	58	14	for	for	ADP
dti-1418	58	15	such	such	ADJ
dti-1418	58	16	common	common	ADJ
dti-1418	58	17	and	and	CCONJ
dti-1418	58	18	refractory	refractory	NOUN
dti-1418	58	19	arrhythmia	arrhythmia	NOUN
dti-1418	58	20	.	.	PUNCT
dti-1418	59	1	vernakalant	vernakalant	NOUN
dti-1418	59	2	,	,	PUNCT
dti-1418	59	3	a	a	DET
dti-1418	59	4	relatively	relatively	ADV
dti-1418	59	5	new	new	ADJ
dti-1418	59	6	aad	aad	NOUN
dti-1418	59	7	with	with	ADP
dti-1418	59	8	atrial	atrial	ADJ
dti-1418	59	9	-	-	PUNCT
dti-1418	59	10	selective	selective	ADJ
dti-1418	59	11	anti	anti	ADJ
dti-1418	59	12	-	-	ADJ
dti-1418	59	13	arrhythmic	arrhythmic	ADJ
dti-1418	59	14	activity	activity	NOUN
dti-1418	59	15	,	,	PUNCT
dti-1418	59	16	is	be	AUX
dti-1418	59	17	currently	currently	ADV
dti-1418	59	18	approved	approve	VERB
dti-1418	59	19	in	in	ADP
dti-1418	59	20	the	the	DET
dti-1418	59	21	european	european	PROPN
dti-1418	59	22	union	union	PROPN
dti-1418	59	23	and	and	CCONJ
dti-1418	59	24	in	in	ADP
dti-1418	59	25	many	many	ADJ
dti-1418	59	26	other	other	ADJ
dti-1418	59	27	countries	country	NOUN
dti-1418	59	28	for	for	ADP
dti-1418	59	29	pharmacological	pharmacological	ADJ
dti-1418	59	30	cardioversion	cardioversion	NOUN
dti-1418	59	31	of	of	ADP
dti-1418	59	32	recent	recent	ADJ
dti-1418	59	33	-	-	PUNCT
dti-1418	59	34	onset	onset	NOUN
dti-1418	59	35	af	af	NOUN
dti-1418	59	36	.	.	PROPN
dti-1418	60	1	of	of	ADP
dti-1418	60	2	note	note	NOUN
dti-1418	60	3	,	,	PUNCT
dti-1418	60	4	the	the	DET
dti-1418	60	5	drug	drug	NOUN
dti-1418	60	6	is	be	AUX
dti-1418	60	7	still	still	ADV
dti-1418	60	8	not	not	PART
dti-1418	60	9	approved	approve	VERB
dti-1418	60	10	in	in	ADP
dti-1418	60	11	the	the	DET
dti-1418	60	12	united	united	PROPN
dti-1418	60	13	states	states	PROPN
dti-1418	60	14	;	;	PUNCT
dti-1418	60	15	also	also	ADV
dti-1418	60	16	multicentric	multicentric	ADJ
dti-1418	60	17	cost	cost	NOUN
dti-1418	60	18	effectiveness	effectiveness	NOUN
dti-1418	60	19	studies	study	NOUN
dti-1418	60	20	evaluating	evaluate	VERB
dti-1418	60	21	vernakalant	vernakalant	NOUN
dti-1418	60	22	in	in	ADP
dti-1418	60	23	“	"	PUNCT
dti-1418	60	24	real	real	ADJ
dti-1418	60	25	world	world	NOUN
dti-1418	60	26	”	"	PUNCT
dti-1418	60	27	are	be	AUX
dti-1418	60	28	still	still	ADV
dti-1418	60	29	missing	miss	VERB
dti-1418	60	30	.	.	PUNCT
dti-1418	61	1	nevertheless	nevertheless	ADV
dti-1418	61	2	,	,	PUNCT
dti-1418	61	3	current	current	ADJ
dti-1418	61	4	medical	medical	ADJ
dti-1418	61	5	literature	literature	NOUN
dti-1418	61	6	showed	show	VERB
dti-1418	61	7	that	that	DET
dti-1418	61	8	vernakalant	vernakalant	NOUN
dti-1418	61	9	is	be	AUX
dti-1418	61	10	safe	safe	ADJ
dti-1418	61	11	and	and	CCONJ
dti-1418	61	12	efficacious	efficacious	ADJ
dti-1418	61	13	as	as	ADP
dti-1418	61	14	anti	anti	ADJ
dti-1418	61	15	-	-	ADJ
dti-1418	61	16	arrhythmic	arrhythmic	ADJ
dti-1418	61	17	agent	agent	NOUN
dti-1418	61	18	for	for	ADP
dti-1418	61	19	terminating	terminate	VERB
dti-1418	61	20	recent	recent	ADJ
dti-1418	61	21	-	-	PUNCT
dti-1418	61	22	onset	onset	NOUN
dti-1418	61	23	af	af	PROPN
dti-1418	61	24	.	.	PUNCT
dti-1418	62	1	author	author	NOUN
dti-1418	62	2	contributions	contribution	NOUN
dti-1418	62	3	conceived	conceive	VERB
dti-1418	62	4	the	the	DET
dti-1418	62	5	concepts	concept	NOUN
dti-1418	62	6	:	:	PUNCT
dti-1418	62	7	ak	ak	PROPN
dti-1418	62	8	.	.	PROPN
dti-1418	62	9	analyzed	analyze	VERB
dti-1418	62	10	the	the	DET
dti-1418	62	11	data	datum	NOUN
dti-1418	62	12	:	:	PUNCT
dti-1418	62	13	ak	ak	PROPN
dti-1418	62	14	.	.	PROPN
dti-1418	62	15	wrote	write	VERB
dti-1418	62	16	the	the	DET
dti-1418	62	17	first	first	ADJ
dti-1418	62	18	draft	draft	NOUN
dti-1418	62	19	of	of	ADP
dti-1418	62	20	the	the	DET
dti-1418	62	21	manuscript	manuscript	NOUN
dti-1418	62	22	:	:	PUNCT
dti-1418	62	23	ak	ak	PROPN
dti-1418	62	24	.	.	PROPN
dti-1418	62	25	contributed	contribute	VERB
dti-1418	62	26	to	to	ADP
dti-1418	62	27	the	the	DET
dti-1418	62	28	writing	writing	NOUN
dti-1418	62	29	of	of	ADP
dti-1418	62	30	the	the	DET
dti-1418	62	31	manuscript	manuscript	NOUN
dti-1418	62	32	:	:	PUNCT
dti-1418	62	33	ak	ak	AUX
dti-1418	62	34	.	.	PROPN
dti-1418	62	35	agree	agree	VERB
dti-1418	62	36	with	with	ADP
dti-1418	62	37	manuscript	manuscript	NOUN
dti-1418	62	38	results	result	NOUN
dti-1418	62	39	and	and	CCONJ
dti-1418	62	40	conclusions	conclusion	NOUN
dti-1418	62	41	:	:	PUNCT
dti-1418	62	42	ak	ak	PROPN
dti-1418	62	43	.	.	PROPN
dti-1418	62	44	developed	develop	VERB
dti-1418	62	45	the	the	DET
dti-1418	62	46	structure	structure	NOUN
dti-1418	62	47	and	and	CCONJ
dti-1418	62	48	arguments	argument	NOUN
dti-1418	62	49	for	for	ADP
dti-1418	62	50	the	the	DET
dti-1418	62	51	paper	paper	NOUN
dti-1418	62	52	:	:	PUNCT
dti-1418	62	53	ak	ak	PROPN
dti-1418	62	54	.	.	PROPN
dti-1418	62	55	made	make	VERB
dti-1418	62	56	critical	critical	ADJ
dti-1418	62	57	revisions	revision	NOUN
dti-1418	62	58	and	and	CCONJ
dti-1418	62	59	approved	approve	VERB
dti-1418	62	60	final	final	ADJ
dti-1418	62	61	version	version	NOUN
dti-1418	62	62	:	:	PUNCT
dti-1418	62	63	ak	ak	PROPN
dti-1418	62	64	.	.	PROPN
dti-1418	62	65	orcid	orcid	PROPN
dti-1418	63	1	i	i	PRON
dti-1418	63	2	d	d	PROPN
dti-1418	63	3	antoine	antoine	PROPN
dti-1418	63	4	kossaify	kossaify	VERB
dti-1418	63	5	https://orcid.org/0000-0002-7104-1323	https://orcid.org/0000-0002-7104-1323	PROPN
dti-1418	63	6	references	reference	NOUN
dti-1418	63	7	1	1	NUM
dti-1418	63	8	.	.	PUNCT
dti-1418	63	9	stewart	stewart	PROPN
dti-1418	63	10	s	s	PROPN
dti-1418	63	11	,	,	PUNCT
dti-1418	63	12	hart	hart	PROPN
dti-1418	63	13	cl	cl	PROPN
dti-1418	63	14	,	,	PUNCT
dti-1418	63	15	hole	hole	NOUN
dti-1418	63	16	dj	dj	NOUN
dti-1418	63	17	,	,	PUNCT
dti-1418	63	18	mcmurray	mcmurray	PROPN
dti-1418	63	19	jj	jj	PROPN
dti-1418	63	20	.	.	PROPN
dti-1418	64	1	population	population	NOUN
dti-1418	64	2	prevalence	prevalence	NOUN
dti-1418	64	3	,	,	PUNCT
dti-1418	64	4	incidence	incidence	NOUN
dti-1418	64	5	,	,	PUNCT
dti-1418	64	6	and	and	CCONJ
dti-1418	64	7	predictors	predictor	NOUN
dti-1418	64	8	of	of	ADP
dti-1418	64	9	atrial	atrial	ADJ
dti-1418	64	10	fibrillation	fibrillation	NOUN
dti-1418	64	11	in	in	ADP
dti-1418	64	12	the	the	DET
dti-1418	64	13	renfrew	renfrew	NOUN
dti-1418	64	14	/	/	SYM
dti-1418	64	15	paisley	paisley	PROPN
dti-1418	64	16	study	study	NOUN
dti-1418	64	17	.	.	PUNCT
dti-1418	65	1	heart	heart	NOUN
dti-1418	65	2	.	.	PUNCT
dti-1418	66	1	2001;86:516–521	2001;86:516–521	NUM
dti-1418	66	2	.	.	NOUN
dti-1418	67	1	2	2	X
dti-1418	67	2	.	.	X
dti-1418	67	3	naccarelli	naccarelli	PROPN
dti-1418	67	4	gv	gv	PROPN
dti-1418	67	5	,	,	PUNCT
dti-1418	67	6	varker	varker	PROPN
dti-1418	67	7	h	h	PROPN
dti-1418	67	8	,	,	PUNCT
dti-1418	67	9	lin	lin	PROPN
dti-1418	67	10	j	j	PROPN
dti-1418	67	11	,	,	PUNCT
dti-1418	67	12	schulman	schulman	PROPN
dti-1418	67	13	kl	kl	PROPN
dti-1418	67	14	.	.	PUNCT
dti-1418	68	1	increasing	increase	VERB
dti-1418	68	2	prevalence	prevalence	NOUN
dti-1418	68	3	of	of	ADP
dti-1418	68	4	atrial	atrial	ADJ
dti-1418	68	5	fibrillation	fibrillation	NOUN
dti-1418	68	6	and	and	CCONJ
dti-1418	68	7	flutter	flutter	NOUN
dti-1418	68	8	in	in	ADP
dti-1418	68	9	the	the	DET
dti-1418	68	10	united	united	PROPN
dti-1418	68	11	states	states	PROPN
dti-1418	68	12	.	.	PUNCT
dti-1418	69	1	am	be	AUX
dti-1418	69	2	j	j	PROPN
dti-1418	69	3	cardiol	cardiol	NOUN
dti-1418	69	4	.	.	PUNCT
dti-1418	70	1	2009;104:1534–1539	2009;104:1534–1539	X
dti-1418	70	2	.	.	PUNCT
dti-1418	71	1	3	3	X
dti-1418	71	2	.	.	X
dti-1418	71	3	kirchhof	kirchhof	PROPN
dti-1418	71	4	p	p	X
dti-1418	71	5	,	,	PUNCT
dti-1418	71	6	benussi	benussi	PROPN
dti-1418	71	7	s	s	PROPN
dti-1418	71	8	,	,	PUNCT
dti-1418	71	9	kotecha	kotecha	PROPN
dti-1418	71	10	d	d	PROPN
dti-1418	71	11	,	,	PUNCT
dti-1418	71	12	et	et	PROPN
dti-1418	71	13	al	al	PROPN
dti-1418	71	14	.	.	PROPN
dti-1418	71	15	2016	2016	NUM
dti-1418	71	16	esc	esc	NOUN
dti-1418	71	17	guidelines	guideline	NOUN
dti-1418	71	18	for	for	ADP
dti-1418	71	19	the	the	DET
dti-1418	71	20	management	management	NOUN
dti-1418	71	21	of	of	ADP
dti-1418	71	22	atrial	atrial	ADJ
dti-1418	71	23	fibrillation	fibrillation	NOUN
dti-1418	71	24	developed	develop	VERB
dti-1418	71	25	in	in	ADP
dti-1418	71	26	collaboration	collaboration	NOUN
dti-1418	71	27	with	with	ADP
dti-1418	71	28	eacts	eact	NOUN
dti-1418	71	29	.	.	PUNCT
dti-1418	72	1	europace	europace	NOUN
dti-1418	72	2	.	.	PUNCT
dti-1418	73	1	2016;18:1609–1678	2016;18:1609–1678	NUM
dti-1418	73	2	.	.	NOUN
dti-1418	74	1	4	4	NUM
dti-1418	74	2	.	.	X
dti-1418	74	3	anderson	anderson	PROPN
dti-1418	74	4	jl	jl	PROPN
dti-1418	74	5	,	,	PUNCT
dti-1418	74	6	halperin	halperin	PROPN
dti-1418	74	7	jl	jl	PROPN
dti-1418	74	8	,	,	PUNCT
dti-1418	74	9	albert	albert	PROPN
dti-1418	74	10	nm	nm	PROPN
dti-1418	74	11	,	,	PUNCT
dti-1418	74	12	et	et	PROPN
dti-1418	74	13	al	al	PROPN
dti-1418	74	14	.	.	PUNCT
dti-1418	74	15	management	management	NOUN
dti-1418	74	16	of	of	ADP
dti-1418	74	17	patients	patient	NOUN
dti-1418	74	18	with	with	ADP
dti-1418	74	19	atrial	atrial	ADJ
dti-1418	74	20	fibrillation	fibrillation	NOUN
dti-1418	74	21	.	.	PUNCT
dti-1418	75	1	j	j	PROPN
dti-1418	75	2	am	be	AUX
dti-1418	75	3	coll	coll	PROPN
dti-1418	75	4	cardiol	cardiol	NOUN
dti-1418	75	5	.	.	PUNCT
dti-1418	76	1	2013;61:1935–1944	2013;61:1935–1944	NUM
dti-1418	76	2	.	.	PUNCT
dti-1418	77	1	5	5	NUM
dti-1418	77	2	.	.	PUNCT
dti-1418	77	3	manolis	manolis	PROPN
dti-1418	77	4	as	as	ADP
dti-1418	77	5	.	.	PROPN
dti-1418	77	6	rhythm	rhythm	PROPN
dti-1418	77	7	or	or	CCONJ
dti-1418	77	8	rate	rate	NOUN
dti-1418	77	9	control	control	NOUN
dti-1418	77	10	management	management	NOUN
dti-1418	77	11	of	of	ADP
dti-1418	77	12	atrial	atrial	ADJ
dti-1418	77	13	fibrillation	fibrillation	NOUN
dti-1418	77	14	:	:	PUNCT
dti-1418	77	15	an	an	DET
dti-1418	77	16	overrated	overrated	ADJ
dti-1418	77	17	dilemma	dilemma	NOUN
dti-1418	77	18	.	.	PUNCT
dti-1418	78	1	hellenic	hellenic	PROPN
dti-1418	78	2	j	j	PROPN
dti-1418	78	3	cardiol	cardiol	NOUN
dti-1418	78	4	.	.	PUNCT
dti-1418	79	1	2015;56:495–500	2015;56:495–500	NUM
dti-1418	79	2	.	.	PUNCT
dti-1418	80	1	6	6	NUM
dti-1418	80	2	.	.	X
dti-1418	80	3	camm	camm	PROPN
dti-1418	80	4	aj	aj	PROPN
dti-1418	80	5	,	,	PUNCT
dti-1418	80	6	savelieva	savelieva	PROPN
dti-1418	80	7	i.	i.	PROPN
dti-1418	80	8	atrial	atrial	PROPN
dti-1418	80	9	fibrillation	fibrillation	NOUN
dti-1418	80	10	:	:	PUNCT
dti-1418	80	11	the	the	DET
dti-1418	80	12	rate	rate	NOUN
dti-1418	80	13	versus	versus	ADP
dti-1418	80	14	rhythm	rhythm	PROPN
dti-1418	80	15	management	management	NOUN
dti-1418	80	16	controversy	controversy	NOUN
dti-1418	80	17	.	.	PUNCT
dti-1418	81	1	j	j	PROPN
dti-1418	81	2	r	r	PROPN
dti-1418	81	3	coll	coll	PROPN
dti-1418	81	4	physicians	physician	NOUN
dti-1418	81	5	edinb	edinb	NOUN
dti-1418	81	6	.	.	PUNCT
dti-1418	82	1	2012;42:23–34	2012;42:23–34	NUM
dti-1418	82	2	.	.	X
dti-1418	83	1	7	7	X
dti-1418	83	2	.	.	X
dti-1418	83	3	camm	camm	PROPN
dti-1418	83	4	aj	aj	PROPN
dti-1418	83	5	,	,	PUNCT
dti-1418	83	6	breithardt	breithardt	PROPN
dti-1418	83	7	g	g	PROPN
dti-1418	83	8	,	,	PUNCT
dti-1418	83	9	crijns	crijns	NOUN
dti-1418	83	10	h	h	NOUN
dti-1418	83	11	,	,	PUNCT
dti-1418	83	12	et	et	PROPN
dti-1418	83	13	al	al	PROPN
dti-1418	83	14	.	.	PUNCT
dti-1418	84	1	real	real	ADJ
dti-1418	84	2	-	-	PUNCT
dti-1418	84	3	life	life	NOUN
dti-1418	84	4	observations	observation	NOUN
dti-1418	84	5	of	of	ADP
dti-1418	84	6	clinical	clinical	ADJ
dti-1418	84	7	outcomes	outcome	NOUN
dti-1418	84	8	with	with	ADP
dti-1418	84	9	rhythm	rhythm	NOUN
dti-1418	84	10	-	-	PUNCT
dti-1418	84	11	and	and	CCONJ
dti-1418	84	12	rate	rate	NOUN
dti-1418	84	13	-	-	PUNCT
dti-1418	84	14	control	control	NOUN
dti-1418	84	15	therapies	therapy	NOUN
dti-1418	84	16	for	for	ADP
dti-1418	84	17	atrial	atrial	ADJ
dti-1418	84	18	fibrillation	fibrillation	NOUN
dti-1418	84	19	recordaf	recordaf	NOUN
dti-1418	84	20	.	.	PUNCT
dti-1418	85	1	j	j	PROPN
dti-1418	85	2	am	be	AUX
dti-1418	85	3	coll	coll	PROPN
dti-1418	85	4	cardiol	cardiol	NOUN
dti-1418	85	5	.	.	PUNCT
dti-1418	86	1	2011;58:493–501	2011;58:493–501	NUM
dti-1418	86	2	.	.	NOUN
dti-1418	86	3	8	8	NUM
dti-1418	86	4	.	.	X
dti-1418	87	1	savelieva	savelieva	PROPN
dti-1418	87	2	i	i	PRON
dti-1418	87	3	,	,	PUNCT
dti-1418	87	4	graydon	graydon	PROPN
dti-1418	87	5	r	r	PROPN
dti-1418	87	6	,	,	PUNCT
dti-1418	87	7	camm	camm	PROPN
dti-1418	87	8	aj	aj	PROPN
dti-1418	87	9	.	.	PROPN
dti-1418	87	10	pharmacological	pharmacological	ADJ
dti-1418	87	11	cardioversion	cardioversion	NOUN
dti-1418	87	12	of	of	ADP
dti-1418	87	13	atrial	atrial	ADJ
dti-1418	87	14	fibrillation	fibrillation	NOUN
dti-1418	87	15	with	with	ADP
dti-1418	87	16	vernakalant	vernakalant	NOUN
dti-1418	87	17	:	:	PUNCT
dti-1418	87	18	evidence	evidence	NOUN
dti-1418	87	19	in	in	ADP
dti-1418	87	20	support	support	NOUN
dti-1418	87	21	of	of	ADP
dti-1418	87	22	the	the	DET
dti-1418	87	23	esc	esc	NOUN
dti-1418	87	24	guidelines	guideline	NOUN
dti-1418	87	25	.	.	PUNCT
dti-1418	88	1	europace	europace	NOUN
dti-1418	88	2	.	.	PUNCT
dti-1418	89	1	2014;16:162–173	2014;16:162–173	NOUN
dti-1418	89	2	.	.	PUNCT
dti-1418	90	1	9	9	X
dti-1418	90	2	.	.	X
dti-1418	90	3	camm	camm	PROPN
dti-1418	90	4	aj	aj	PROPN
dti-1418	90	5	.	.	PUNCT
dti-1418	91	1	the	the	DET
dti-1418	91	2	vernakalant	vernakalant	NOUN
dti-1418	91	3	story	story	NOUN
dti-1418	91	4	:	:	PUNCT
dti-1418	91	5	how	how	SCONJ
dti-1418	91	6	did	do	AUX
dti-1418	91	7	it	it	PRON
dti-1418	91	8	come	come	VERB
dti-1418	91	9	to	to	ADP
dti-1418	91	10	approval	approval	NOUN
dti-1418	91	11	in	in	ADP
dti-1418	91	12	europe	europe	PROPN
dti-1418	91	13	and	and	CCONJ
dti-1418	91	14	what	what	PRON
dti-1418	91	15	is	be	AUX
dti-1418	91	16	the	the	DET
dti-1418	91	17	delay	delay	NOUN
dti-1418	91	18	in	in	ADP
dti-1418	91	19	the	the	DET
dti-1418	91	20	u.s.a	u.s.a	NOUN
dti-1418	91	21	.	.	PUNCT
dti-1418	92	1	curr	curr	PROPN
dti-1418	92	2	cardiol	cardiol	PROPN
dti-1418	92	3	rev	rev	PROPN
dti-1418	92	4	.	.	PROPN
dti-1418	93	1	2014;10:309–314	2014;10:309–314	NUM
dti-1418	93	2	.	.	PUNCT
dti-1418	94	1	10	10	NUM
dti-1418	94	2	.	.	PUNCT
dti-1418	95	1	dudink	dudink	PROPN
dti-1418	95	2	e	e	PROPN
dti-1418	95	3	,	,	PUNCT
dti-1418	95	4	essers	esser	NOUN
dti-1418	95	5	b	b	NUM
dti-1418	95	6	,	,	PUNCT
dti-1418	95	7	holvoet	holvoet	VERB
dti-1418	95	8	w	w	PROPN
dti-1418	95	9	,	,	PUNCT
dti-1418	95	10	et	et	PROPN
dti-1418	95	11	al	al	PROPN
dti-1418	95	12	.	.	PUNCT
dti-1418	95	13	acute	acute	ADJ
dti-1418	95	14	cardioversion	cardioversion	NOUN
dti-1418	95	15	vs	vs	ADP
dti-1418	95	16	a	a	DET
dti-1418	95	17	wait	wait	VERB
dti-1418	95	18	-	-	PUNCT
dti-1418	95	19	and	and	CCONJ
dti-1418	95	20	-	-	PUNCT
dti-1418	95	21	see	see	VERB
dti-1418	95	22	approach	approach	NOUN
dti-1418	95	23	for	for	ADP
dti-1418	95	24	recent	recent	ADJ
dti-1418	95	25	-	-	PUNCT
dti-1418	95	26	onset	onset	VERB
dti-1418	95	27	symptomatic	symptomatic	ADJ
dti-1418	95	28	atrial	atrial	ADJ
dti-1418	95	29	fibrillation	fibrillation	NOUN
dti-1418	95	30	in	in	ADP
dti-1418	95	31	the	the	DET
dti-1418	95	32	emergency	emergency	NOUN
dti-1418	95	33	department	department	NOUN
dti-1418	95	34	:	:	PUNCT
dti-1418	95	35	rationale	rationale	NOUN
dti-1418	95	36	and	and	CCONJ
dti-1418	95	37	design	design	NOUN
dti-1418	95	38	of	of	ADP
dti-1418	95	39	the	the	DET
dti-1418	95	40	randomized	randomized	ADJ
dti-1418	95	41	acwas	acwas	NOUN
dti-1418	95	42	trial	trial	NOUN
dti-1418	95	43	.	.	PUNCT
dti-1418	96	1	am	be	AUX
dti-1418	96	2	heart	heart	NOUN
dti-1418	96	3	j.	j.	PROPN
dti-1418	96	4	2017;183:49–53	2017;183:49–53	PROPN
dti-1418	96	5	.	.	PROPN
dti-1418	97	1	11	11	NUM
dti-1418	97	2	.	.	PUNCT
dti-1418	98	1	saborido	saborido	PROPN
dti-1418	98	2	cm	cm	PROPN
dti-1418	98	3	,	,	PUNCT
dti-1418	98	4	hockenhull	hockenhull	PROPN
dti-1418	98	5	j	j	PROPN
dti-1418	98	6	,	,	PUNCT
dti-1418	98	7	bagust	bagust	PROPN
dti-1418	98	8	a	a	PROPN
dti-1418	98	9	,	,	PUNCT
dti-1418	98	10	boland	boland	PROPN
dti-1418	98	11	a	a	X
dti-1418	98	12	,	,	PUNCT
dti-1418	98	13	dickson	dickson	PROPN
dti-1418	98	14	r	r	PROPN
dti-1418	98	15	,	,	PUNCT
dti-1418	98	16	todd	todd	PROPN
dti-1418	98	17	d.	d.	PROPN
dti-1418	98	18	systematic	systematic	PROPN
dti-1418	98	19	review	review	PROPN
dti-1418	98	20	and	and	CCONJ
dti-1418	98	21	cost	cost	NOUN
dti-1418	98	22	-	-	PUNCT
dti-1418	98	23	effectiveness	effectiveness	NOUN
dti-1418	98	24	evaluation	evaluation	NOUN
dti-1418	98	25	of	of	ADP
dti-1418	98	26	“	"	PUNCT
dti-1418	98	27	pill	pill	NOUN
dti-1418	98	28	-	-	PUNCT
dti-1418	98	29	in	in	ADP
dti-1418	98	30	-	-	PUNCT
dti-1418	98	31	the	the	DET
dti-1418	98	32	-	-	PUNCT
dti-1418	98	33	pocket	pocket	NOUN
dti-1418	98	34	”	"	PUNCT
dti-1418	98	35	strategy	strategy	NOUN
dti-1418	98	36	for	for	ADP
dti-1418	98	37	paroxysmal	paroxysmal	ADJ
dti-1418	98	38	atrial	atrial	ADJ
dti-1418	98	39	fibrillation	fibrillation	NOUN
dti-1418	98	40	compared	compare	VERB
dti-1418	98	41	to	to	ADP
dti-1418	98	42	episodic	episodic	ADJ
dti-1418	98	43	in	in	ADP
dti-1418	98	44	-	-	PUNCT
dti-1418	98	45	hospital	hospital	NOUN
dti-1418	98	46	treatment	treatment	NOUN
dti-1418	98	47	or	or	CCONJ
dti-1418	98	48	continuous	continuous	ADJ
dti-1418	98	49	antiarrhythmic	antiarrhythmic	ADJ
dti-1418	98	50	drug	drug	NOUN
dti-1418	98	51	therapy	therapy	NOUN
dti-1418	98	52	.	.	PUNCT
dti-1418	99	1	health	health	PROPN
dti-1418	99	2	technol	technol	PROPN
dti-1418	99	3	assess	assess	NOUN
dti-1418	99	4	.	.	PUNCT
dti-1418	100	1	2010;14	2010;14	NUM
dti-1418	100	2	:	:	PUNCT
dti-1418	100	3	iii	iii	X
dti-1418	100	4	–	–	PUNCT
dti-1418	100	5	iv	iv	NUM
dti-1418	100	6	,	,	PUNCT
dti-1418	100	7	1–75	1–75	PROPN
dti-1418	100	8	.	.	PUNCT
dti-1418	101	1	12	12	NUM
dti-1418	101	2	.	.	PUNCT
dti-1418	102	1	roy	roy	PROPN
dti-1418	102	2	d	d	PROPN
dti-1418	102	3	,	,	PUNCT
dti-1418	102	4	rowe	rowe	PROPN
dti-1418	102	5	bh	bh	PROPN
dti-1418	102	6	,	,	PUNCT
dti-1418	102	7	stiell	stiell	PROPN
dti-1418	102	8	ig	ig	PROPN
dti-1418	102	9	,	,	PUNCT
dti-1418	102	10	et	et	PROPN
dti-1418	102	11	al	al	PROPN
dti-1418	102	12	.	.	PUNCT
dti-1418	103	1	a	a	DET
dti-1418	103	2	randomized	randomized	ADJ
dti-1418	103	3	,	,	PUNCT
dti-1418	103	4	controlled	control	VERB
dti-1418	103	5	trial	trial	NOUN
dti-1418	103	6	of	of	ADP
dti-1418	103	7	rsd1235	rsd1235	NOUN
dti-1418	103	8	,	,	PUNCT
dti-1418	103	9	a	a	DET
dti-1418	103	10	novel	novel	ADJ
dti-1418	103	11	anti	anti	ADJ
dti-1418	103	12	-	-	ADJ
dti-1418	103	13	arrhythmic	arrhythmic	ADJ
dti-1418	103	14	agent	agent	NOUN
dti-1418	103	15	,	,	PUNCT
dti-1418	103	16	in	in	ADP
dti-1418	103	17	the	the	DET
dti-1418	103	18	treatment	treatment	NOUN
dti-1418	103	19	of	of	ADP
dti-1418	103	20	recent	recent	ADJ
dti-1418	103	21	onset	onset	VERB
dti-1418	103	22	atrial	atrial	ADJ
dti-1418	103	23	fibrillation	fibrillation	NOUN
dti-1418	103	24	.	.	PUNCT
dti-1418	104	1	j	j	PROPN
dti-1418	104	2	am	be	AUX
dti-1418	104	3	coll	coll	PROPN
dti-1418	104	4	cardiol	cardiol	NOUN
dti-1418	104	5	.	.	PUNCT
dti-1418	105	1	2004:2355–2361	2004:2355–2361	NOUN
dti-1418	105	2	.	.	PUNCT
dti-1418	106	1	13	13	NUM
dti-1418	106	2	.	.	X
dti-1418	106	3	fedida	fedida	PROPN
dti-1418	106	4	d.	d.	PROPN
dti-1418	106	5	vernakalant	vernakalant	PROPN
dti-1418	106	6	(	(	PUNCT
dti-1418	106	7	rsd1235	rsd1235	PROPN
dti-1418	106	8	):	):	PUNCT
dti-1418	106	9	a	a	DET
dti-1418	106	10	novel	novel	NOUN
dti-1418	106	11	,	,	PUNCT
dti-1418	106	12	atrial	atrial	ADJ
dti-1418	106	13	-	-	PUNCT
dti-1418	106	14	selective	selective	ADJ
dti-1418	106	15	antifibrillatory	antifibrillatory	ADJ
dti-1418	106	16	agent	agent	NOUN
dti-1418	106	17	.	.	PUNCT
dti-1418	107	1	expert	expert	NOUN
dti-1418	107	2	opin	opin	NOUN
dti-1418	107	3	investig	investig	NOUN
dti-1418	107	4	drugs	drug	NOUN
dti-1418	107	5	.	.	PUNCT
dti-1418	108	1	2007;16:519–532	2007;16:519–532	NOUN
dti-1418	108	2	.	.	NOUN
dti-1418	108	3	14	14	NUM
dti-1418	108	4	.	.	PUNCT
dti-1418	109	1	camm	camm	PROPN
dti-1418	109	2	aj	aj	PROPN
dti-1418	109	3	,	,	PUNCT
dti-1418	109	4	kirchhof	kirchhof	PROPN
dti-1418	109	5	p	p	NOUN
dti-1418	109	6	,	,	PUNCT
dti-1418	109	7	lip	lip	PROPN
dti-1418	109	8	gy	gy	PROPN
dti-1418	109	9	,	,	PUNCT
dti-1418	109	10	et	et	PROPN
dti-1418	109	11	al	al	PROPN
dti-1418	109	12	.	.	PUNCT
dti-1418	109	13	guidelines	guideline	NOUN
dti-1418	109	14	for	for	ADP
dti-1418	109	15	the	the	DET
dti-1418	109	16	management	management	NOUN
dti-1418	109	17	of	of	ADP
dti-1418	109	18	atrial	atrial	ADJ
dti-1418	109	19	fibrillation	fibrillation	NOUN
dti-1418	109	20	:	:	PUNCT
dti-1418	109	21	the	the	DET
dti-1418	109	22	task	task	NOUN
dti-1418	109	23	force	force	NOUN
dti-1418	109	24	for	for	ADP
dti-1418	109	25	the	the	DET
dti-1418	109	26	management	management	NOUN
dti-1418	109	27	of	of	ADP
dti-1418	109	28	atrial	atrial	ADJ
dti-1418	109	29	fibrillation	fibrillation	NOUN
dti-1418	109	30	of	of	ADP
dti-1418	109	31	the	the	DET
dti-1418	109	32	european	european	ADJ
dti-1418	109	33	society	society	PROPN
dti-1418	109	34	of	of	ADP
dti-1418	109	35	cardiology	cardiology	NOUN
dti-1418	109	36	(	(	PUNCT
dti-1418	109	37	esc	esc	NOUN
dti-1418	109	38	)	)	PUNCT
dti-1418	109	39	.	.	PUNCT
dti-1418	110	1	eur	eur	PROPN
dti-1418	110	2	heart	heart	NOUN
dti-1418	110	3	j.	j.	PROPN
dti-1418	110	4	2010;31:2369–2429	2010;31:2369–2429	PROPN
dti-1418	110	5	.	.	PROPN
dti-1418	110	6	15	15	NUM
dti-1418	110	7	.	.	PUNCT
dti-1418	110	8	finnin	finnin	VERB
dti-1418	110	9	m.	m.	NOUN
dti-1418	110	10	vernakalant	vernakalant	PROPN
dti-1418	110	11	:	:	PUNCT
dti-1418	110	12	a	a	DET
dti-1418	110	13	novel	novel	ADJ
dti-1418	110	14	agent	agent	NOUN
dti-1418	110	15	for	for	ADP
dti-1418	110	16	the	the	DET
dti-1418	110	17	termination	termination	NOUN
dti-1418	110	18	of	of	ADP
dti-1418	110	19	atrial	atrial	ADJ
dti-1418	110	20	fibrillation	fibrillation	NOUN
dti-1418	110	21	.	.	PUNCT
dti-1418	111	1	am	be	AUX
dti-1418	111	2	j	j	PROPN
dti-1418	111	3	health	health	PROPN
dti-1418	111	4	syst	syst	PROPN
dti-1418	111	5	pharm	pharm	PROPN
dti-1418	111	6	.	.	PUNCT
dti-1418	112	1	2010;67:1157–1164	2010;67:1157–1164	PROPN
dti-1418	112	2	.	.	PROPN
dti-1418	112	3	16	16	NUM
dti-1418	112	4	.	.	PUNCT
dti-1418	113	1	wettwer	wettwer	PROPN
dti-1418	113	2	e	e	NOUN
dti-1418	113	3	,	,	PUNCT
dti-1418	113	4	christ	christ	PROPN
dti-1418	113	5	t	t	PROPN
dti-1418	113	6	,	,	PUNCT
dti-1418	113	7	endig	endig	PROPN
dti-1418	113	8	s	s	PROPN
dti-1418	113	9	,	,	PUNCT
dti-1418	113	10	et	et	PROPN
dti-1418	113	11	al	al	PROPN
dti-1418	113	12	.	.	PUNCT
dti-1418	114	1	the	the	DET
dti-1418	114	2	new	new	ADJ
dti-1418	114	3	antiarrhythmic	antiarrhythmic	ADJ
dti-1418	114	4	drug	drug	NOUN
dti-1418	114	5	vernakalant	vernakalant	NOUN
dti-1418	114	6	:	:	PUNCT
dti-1418	114	7	ex	ex	X
dti-1418	114	8	vivo	vivo	ADJ
dti-1418	114	9	study	study	NOUN
dti-1418	114	10	of	of	ADP
dti-1418	114	11	human	human	ADJ
dti-1418	114	12	atrial	atrial	ADJ
dti-1418	114	13	tissue	tissue	NOUN
dti-1418	114	14	from	from	ADP
dti-1418	114	15	sinus	sinus	NOUN
dti-1418	114	16	rhythm	rhythm	NOUN
dti-1418	114	17	and	and	CCONJ
dti-1418	114	18	chronic	chronic	ADJ
dti-1418	114	19	atrial	atrial	ADJ
dti-1418	114	20	fibrillation	fibrillation	NOUN
dti-1418	114	21	.	.	PUNCT
dti-1418	115	1	cardiovasc	cardiovasc	PROPN
dti-1418	115	2	res	re	NOUN
dti-1418	115	3	.	.	PUNCT
dti-1418	116	1	2013;98:145–154	2013;98:145–154	NOUN
dti-1418	116	2	.	.	PUNCT
dti-1418	117	1	17	17	NUM
dti-1418	117	2	.	.	PUNCT
dti-1418	118	1	heidbuchel	heidbuchel	PROPN
dti-1418	118	2	h	h	PROPN
dti-1418	118	3	,	,	PUNCT
dti-1418	118	4	vereecke	vereecke	PROPN
dti-1418	118	5	j	j	PROPN
dti-1418	118	6	,	,	PUNCT
dti-1418	118	7	carmeliet	carmeliet	PROPN
dti-1418	118	8	e.	e.	PROPN
dti-1418	118	9	three	three	NUM
dti-1418	118	10	different	different	ADJ
dti-1418	118	11	potassium	potassium	NOUN
dti-1418	118	12	channels	channel	NOUN
dti-1418	118	13	in	in	ADP
dti-1418	118	14	human	human	ADJ
dti-1418	118	15	atrium	atrium	NOUN
dti-1418	118	16	.	.	PUNCT
dti-1418	119	1	circ	circ	PROPN
dti-1418	119	2	res	re	NOUN
dti-1418	119	3	.	.	PUNCT
dti-1418	120	1	1990;66:1277–1286	1990;66:1277–1286	ADJ
dti-1418	120	2	.	.	PUNCT
dti-1418	121	1	18	18	NUM
dti-1418	121	2	.	.	PUNCT
dti-1418	122	1	dorian	dorian	PROPN
dti-1418	122	2	p	p	X
dti-1418	122	3	,	,	PUNCT
dti-1418	122	4	pinter	pinter	VERB
dti-1418	122	5	a	a	PRON
dti-1418	122	6	,	,	PUNCT
dti-1418	122	7	mangat	mangat	NOUN
dti-1418	122	8	i	i	PROPN
dti-1418	122	9	,	,	PUNCT
dti-1418	122	10	korley	korley	PROPN
dti-1418	122	11	v	v	NOUN
dti-1418	122	12	,	,	PUNCT
dti-1418	122	13	cvitkovic	cvitkovic	ADJ
dti-1418	122	14	ss	ss	PROPN
dti-1418	122	15	,	,	PUNCT
dti-1418	122	16	beatch	beatch	PROPN
dti-1418	122	17	gn	gn	PROPN
dti-1418	122	18	.	.	PUNCT
dti-1418	123	1	the	the	DET
dti-1418	123	2	effect	effect	NOUN
dti-1418	123	3	of	of	ADP
dti-1418	123	4	vernakalant	vernakalant	NOUN
dti-1418	123	5	(	(	PUNCT
dti-1418	123	6	rsd1235	rsd1235	PROPN
dti-1418	123	7	)	)	PUNCT
dti-1418	123	8	,	,	PUNCT
dti-1418	123	9	an	an	DET
dti-1418	123	10	investigational	investigational	ADJ
dti-1418	123	11	antiarrhythmic	antiarrhythmic	ADJ
dti-1418	123	12	agent	agent	NOUN
dti-1418	123	13	,	,	PUNCT
dti-1418	123	14	on	on	ADP
dti-1418	123	15	atrial	atrial	ADJ
dti-1418	123	16	electrophysiology	electrophysiology	NOUN
dti-1418	123	17	in	in	ADP
dti-1418	123	18	humans	human	NOUN
dti-1418	123	19	.	.	PUNCT
dti-1418	124	1	j	j	PROPN
dti-1418	124	2	cardiovasc	cardiovasc	PROPN
dti-1418	124	3	pharmacol	pharmacol	PROPN
dti-1418	124	4	.	.	PUNCT
dti-1418	125	1	2007;50:35–40	2007;50:35–40	NUM
dti-1418	125	2	.	.	X
dti-1418	126	1	19	19	NUM
dti-1418	126	2	.	.	X
dti-1418	126	3	mao	mao	PROPN
dti-1418	127	1	zl	zl	PROPN
dti-1418	127	2	,	,	PUNCT
dti-1418	127	3	wheeler	wheeler	NOUN
dti-1418	127	4	jj	jj	PROPN
dti-1418	127	5	,	,	PUNCT
dti-1418	127	6	clohs	clohs	PROPN
dti-1418	127	7	l	l	PROPN
dti-1418	127	8	,	,	PUNCT
dti-1418	127	9	et	et	PROPN
dti-1418	127	10	al	al	PROPN
dti-1418	127	11	.	.	PUNCT
dti-1418	128	1	pharmacokinetics	pharmacokinetic	NOUN
dti-1418	128	2	of	of	ADP
dti-1418	128	3	novel	novel	ADJ
dti-1418	128	4	atrial	atrial	ADJ
dti-1418	128	5	-	-	PUNCT
dti-1418	128	6	selective	selective	ADJ
dti-1418	128	7	antiarrhythmic	antiarrhythmic	ADJ
dti-1418	128	8	agent	agent	NOUN
dti-1418	128	9	vernakalant	vernakalant	NOUN
dti-1418	128	10	hydrochloride	hydrochloride	NOUN
dti-1418	128	11	injection	injection	NOUN
dti-1418	128	12	(	(	PUNCT
dti-1418	128	13	rsd1235	rsd1235	X
dti-1418	128	14	):	):	PUNCT
dti-1418	128	15	influence	influence	NOUN
dti-1418	128	16	of	of	ADP
dti-1418	128	17	cyp2d6	cyp2d6	NOUN
dti-1418	128	18	expression	expression	NOUN
dti-1418	128	19	on	on	ADP
dti-1418	128	20	other	other	ADJ
dti-1418	128	21	factors	factor	NOUN
dti-1418	128	22	.	.	PUNCT
dti-1418	129	1	j	j	PROPN
dti-1418	129	2	clin	clin	PROPN
dti-1418	129	3	pharmacol	pharmacol	PROPN
dti-1418	129	4	.	.	PUNCT
dti-1418	130	1	2009;49:17–29	2009;49:17–29	NUM
dti-1418	130	2	.	.	X
dti-1418	131	1	20	20	NUM
dti-1418	131	2	.	.	PUNCT
dti-1418	131	3	mao	mao	PROPN
dti-1418	132	1	zl	zl	PROPN
dti-1418	132	2	,	,	PUNCT
dti-1418	132	3	townsend	townsend	PROPN
dti-1418	132	4	rw	rw	PROPN
dti-1418	132	5	,	,	PUNCT
dti-1418	132	6	gao	gao	PROPN
dti-1418	132	7	y	y	PROPN
dti-1418	132	8	,	,	PUNCT
dti-1418	132	9	wheeler	wheeler	NOUN
dti-1418	132	10	jj	jj	PROPN
dti-1418	132	11	,	,	PUNCT
dti-1418	132	12	kastrissios	kastrissios	PROPN
dti-1418	132	13	h	h	PROPN
dti-1418	132	14	,	,	PUNCT
dti-1418	132	15	keirns	keirn	VERB
dti-1418	132	16	j.	j.	PROPN
dti-1418	132	17	population	population	PROPN
dti-1418	132	18	pharmacokinetics	pharmacokinetic	NOUN
dti-1418	132	19	of	of	ADP
dti-1418	132	20	vernakalant	vernakalant	NOUN
dti-1418	132	21	hydrochloride	hydrochloride	NOUN
dti-1418	132	22	injection	injection	NOUN
dti-1418	132	23	(	(	PUNCT
dti-1418	132	24	rsd1235	rsd1235	VERB
dti-1418	132	25	)	)	PUNCT
dti-1418	132	26	in	in	ADP
dti-1418	132	27	patients	patient	NOUN
dti-1418	132	28	with	with	ADP
dti-1418	132	29	atrial	atrial	ADJ
dti-1418	132	30	fibrillation	fibrillation	NOUN
dti-1418	132	31	or	or	CCONJ
dti-1418	132	32	atrial	atrial	ADJ
dti-1418	132	33	flutter	flutter	NOUN
dti-1418	132	34	.	.	PUNCT
dti-1418	133	1	j	j	PROPN
dti-1418	133	2	clin	clin	PROPN
dti-1418	133	3	pharmacol	pharmacol	PROPN
dti-1418	133	4	.	.	PUNCT
dti-1418	134	1	2012;52	2012;52	NUM
dti-1418	134	2	:	:	PUNCT
dti-1418	135	1	1042–1053	1042–1053	NUM
dti-1418	135	2	.	.	PUNCT
dti-1418	136	1	21	21	NUM
dti-1418	136	2	.	.	PUNCT
dti-1418	136	3	mao	mao	PROPN
dti-1418	137	1	zl	zl	PROPN
dti-1418	137	2	,	,	PUNCT
dti-1418	137	3	wheeler	wheeler	NOUN
dti-1418	137	4	jj	jj	PROPN
dti-1418	137	5	,	,	PUNCT
dti-1418	137	6	townsend	townsend	PROPN
dti-1418	137	7	r	r	PROPN
dti-1418	137	8	,	,	PUNCT
dti-1418	137	9	gao	gao	PROPN
dti-1418	137	10	y	y	PROPN
dti-1418	137	11	,	,	PUNCT
dti-1418	137	12	kshirsagar	kshirsagar	PROPN
dti-1418	137	13	s	s	PROPN
dti-1418	137	14	,	,	PUNCT
dti-1418	137	15	keirns	keirn	NOUN
dti-1418	137	16	jj	jj	PROPN
dti-1418	137	17	.	.	PROPN
dti-1418	137	18	population	population	NOUN
dti-1418	137	19	pharmacokinetic	pharmacokinetic	ADJ
dti-1418	137	20	-	-	PUNCT
dti-1418	137	21	pharmacodynamic	pharmacodynamic	ADJ
dti-1418	137	22	analysis	analysis	NOUN
dti-1418	137	23	of	of	ADP
dti-1418	137	24	vernakalant	vernakalant	NOUN
dti-1418	137	25	hydrochloride	hydrochloride	NOUN
dti-1418	137	26	injection	injection	NOUN
dti-1418	137	27	(	(	PUNCT
dti-1418	137	28	rsd1235	rsd1235	VERB
dti-1418	137	29	)	)	PUNCT
dti-1418	137	30	in	in	ADP
dti-1418	137	31	atrial	atrial	ADJ
dti-1418	137	32	fibrillation	fibrillation	NOUN
dti-1418	137	33	or	or	CCONJ
dti-1418	137	34	atrial	atrial	ADJ
dti-1418	137	35	flutter	flutter	NOUN
dti-1418	137	36	.	.	PUNCT
dti-1418	138	1	j	j	PROPN
dti-1418	138	2	pharmacokinet	pharmacokinet	PROPN
dti-1418	138	3	pharmacodyn	pharmacodyn	NOUN
dti-1418	138	4	.	.	PUNCT
dti-1418	139	1	2011;38:541–562	2011;38:541–562	NUM
dti-1418	139	2	.	.	PUNCT
dti-1418	140	1	22	22	NUM
dti-1418	140	2	.	.	PUNCT
dti-1418	141	1	cialdella	cialdella	PROPN
dti-1418	141	2	p	p	NOUN
dti-1418	141	3	,	,	PUNCT
dti-1418	141	4	pedicino	pedicino	NOUN
dti-1418	141	5	d	d	NOUN
dti-1418	141	6	,	,	PUNCT
dti-1418	141	7	santangeli	santangeli	ADJ
dti-1418	141	8	p.	p.	NOUN
dti-1418	141	9	novel	novel	ADJ
dti-1418	141	10	agents	agent	NOUN
dti-1418	141	11	for	for	ADP
dti-1418	141	12	the	the	DET
dti-1418	141	13	acute	acute	PROPN
dti-1418	141	14	conversion	conversion	NOUN
dti-1418	141	15	of	of	ADP
dti-1418	141	16	atrial	atrial	ADJ
dti-1418	141	17	fibrillation	fibrillation	NOUN
dti-1418	141	18	:	:	PUNCT
dti-1418	141	19	focus	focus	VERB
dti-1418	141	20	on	on	ADP
dti-1418	141	21	vernakalant	vernakalant	NOUN
dti-1418	141	22	.	.	PUNCT
dti-1418	142	1	recent	recent	ADJ
dti-1418	142	2	pat	pat	PROPN
dti-1418	142	3	cardiovasc	cardiovasc	PROPN
dti-1418	142	4	drug	drug	PROPN
dti-1418	142	5	discov	discov	NOUN
dti-1418	142	6	.	.	PUNCT
dti-1418	143	1	2011;6:1–8	2011;6:1–8	PROPN
dti-1418	143	2	.	.	PROPN
dti-1418	143	3	23	23	NUM
dti-1418	143	4	.	.	PUNCT
dti-1418	144	1	roy	roy	PROPN
dti-1418	144	2	d	d	PROPN
dti-1418	144	3	,	,	PUNCT
dti-1418	144	4	pratt	pratt	PROPN
dti-1418	144	5	cm	cm	PROPN
dti-1418	144	6	,	,	PUNCT
dti-1418	144	7	torp	torp	PROPN
dti-1418	144	8	-	-	PROPN
dti-1418	144	9	pedersen	pedersen	PROPN
dti-1418	144	10	c	c	PROPN
dti-1418	144	11	,	,	PUNCT
dti-1418	144	12	et	et	PROPN
dti-1418	144	13	al	al	PROPN
dti-1418	144	14	.	.	PROPN
dti-1418	144	15	vernakalant	vernakalant	PROPN
dti-1418	144	16	hydrochloride	hydrochloride	NOUN
dti-1418	144	17	for	for	ADP
dti-1418	144	18	rapid	rapid	ADJ
dti-1418	144	19	conversion	conversion	NOUN
dti-1418	144	20	of	of	ADP
dti-1418	144	21	atrial	atrial	ADJ
dti-1418	144	22	fibrillation	fibrillation	NOUN
dti-1418	144	23	:	:	PUNCT
dti-1418	144	24	a	a	DET
dti-1418	144	25	phase	phase	NOUN
dti-1418	144	26	3	3	NUM
dti-1418	144	27	,	,	PUNCT
dti-1418	144	28	randomized	randomize	VERB
dti-1418	144	29	,	,	PUNCT
dti-1418	144	30	placebo	placebo	NOUN
dti-1418	144	31	-	-	PUNCT
dti-1418	144	32	controlled	control	VERB
dti-1418	144	33	trial	trial	NOUN
dti-1418	144	34	.	.	PUNCT
dti-1418	145	1	circulation	circulation	NOUN
dti-1418	145	2	.	.	PUNCT
dti-1418	146	1	2008;117:1518–1525	2008;117:1518–1525	X
dti-1418	146	2	.	.	PUNCT
dti-1418	147	1	24	24	NUM
dti-1418	147	2	.	.	PUNCT
dti-1418	148	1	kowey	kowey	PROPN
dti-1418	148	2	pr	pr	PROPN
dti-1418	148	3	,	,	PUNCT
dti-1418	148	4	dorian	dorian	PROPN
dti-1418	148	5	p	p	PROPN
dti-1418	148	6	,	,	PUNCT
dti-1418	148	7	mitchell	mitchell	PROPN
dti-1418	148	8	lb	lb	PROPN
dti-1418	148	9	,	,	PUNCT
dti-1418	148	10	et	et	PROPN
dti-1418	148	11	al	al	PROPN
dti-1418	148	12	;	;	PUNCT
dti-1418	148	13	atrial	atrial	ADJ
dti-1418	148	14	arrhythmia	arrhythmia	NOUN
dti-1418	148	15	conversion	conversion	NOUN
dti-1418	148	16	trial	trial	NOUN
dti-1418	148	17	investigators	investigator	NOUN
dti-1418	148	18	.	.	PUNCT
dti-1418	149	1	vernakalant	vernakalant	VERB
dti-1418	149	2	hydrochloride	hydrochloride	NOUN
dti-1418	149	3	for	for	ADP
dti-1418	149	4	the	the	DET
dti-1418	149	5	rapid	rapid	ADJ
dti-1418	149	6	conversion	conversion	NOUN
dti-1418	149	7	of	of	ADP
dti-1418	149	8	atrial	atrial	ADJ
dti-1418	149	9	fibrillation	fibrillation	NOUN
dti-1418	149	10	after	after	ADP
dti-1418	149	11	cardiac	cardiac	ADJ
dti-1418	149	12	surgery	surgery	NOUN
dti-1418	149	13	:	:	PUNCT
dti-1418	149	14	a	a	DET
dti-1418	149	15	randomized	randomized	ADJ
dti-1418	149	16	,	,	PUNCT
dti-1418	149	17	double	double	ADJ
dti-1418	149	18	-	-	PUNCT
dti-1418	149	19	blind	blind	ADJ
dti-1418	149	20	,	,	PUNCT
dti-1418	149	21	placebo	placebo	NOUN
dti-1418	149	22	-	-	PUNCT
dti-1418	149	23	controlled	control	VERB
dti-1418	149	24	trial	trial	NOUN
dti-1418	149	25	.	.	PUNCT
dti-1418	150	1	circ	circ	PROPN
dti-1418	150	2	arrhythm	arrhythm	PROPN
dti-1418	150	3	electrophysiol	electrophysiol	PROPN
dti-1418	150	4	.	.	PUNCT
dti-1418	151	1	2009;2:652–659	2009;2:652–659	NUM
dti-1418	151	2	.	.	NOUN
dti-1418	151	3	25	25	NUM
dti-1418	151	4	.	.	PUNCT
dti-1418	152	1	pratt	pratt	PROPN
dti-1418	152	2	cm	cm	PROPN
dti-1418	152	3	,	,	PUNCT
dti-1418	152	4	roy	roy	PROPN
dti-1418	152	5	d	d	PROPN
dti-1418	152	6	,	,	PUNCT
dti-1418	152	7	torp	torp	PROPN
dti-1418	152	8	-	-	PROPN
dti-1418	152	9	pedersen	pedersen	PROPN
dti-1418	152	10	c	c	NOUN
dti-1418	152	11	,	,	PUNCT
dti-1418	152	12	et	et	PROPN
dti-1418	152	13	al	al	PROPN
dti-1418	152	14	;	;	PUNCT
dti-1418	152	15	atrial	atrial	ADJ
dti-1418	152	16	arrhythmia	arrhythmia	NOUN
dti-1418	152	17	conversion	conversion	NOUN
dti-1418	152	18	trial	trial	NOUN
dti-1418	152	19	investigators	investigator	NOUN
dti-1418	152	20	.	.	PUNCT
dti-1418	153	1	usefulness	usefulness	NOUN
dti-1418	153	2	of	of	ADP
dti-1418	153	3	vernakalant	vernakalant	NOUN
dti-1418	153	4	hydrochloride	hydrochloride	NOUN
dti-1418	153	5	injection	injection	NOUN
dti-1418	153	6	for	for	ADP
dti-1418	153	7	rapid	rapid	ADJ
dti-1418	153	8	conversion	conversion	NOUN
dti-1418	153	9	of	of	ADP
dti-1418	153	10	atrial	atrial	ADJ
dti-1418	153	11	fibrillation	fibrillation	NOUN
dti-1418	153	12	.	.	PUNCT
dti-1418	154	1	am	be	AUX
dti-1418	154	2	j	j	PROPN
dti-1418	154	3	cardiol	cardiol	NOUN
dti-1418	154	4	.	.	PUNCT
dti-1418	155	1	2010;106:1277–1283	2010;106:1277–1283	NUM
dti-1418	155	2	.	.	X
dti-1418	156	1	26	26	NUM
dti-1418	156	2	.	.	PUNCT
dti-1418	157	1	stiell	stiell	PROPN
dti-1418	157	2	ig	ig	PROPN
dti-1418	157	3	,	,	PUNCT
dti-1418	157	4	roos	roo	NOUN
dti-1418	157	5	js	js	PROPN
dti-1418	157	6	,	,	PUNCT
dti-1418	157	7	kavanagh	kavanagh	PROPN
dti-1418	157	8	km	km	PROPN
dti-1418	157	9	,	,	PUNCT
dti-1418	157	10	dickinson	dickinson	PROPN
dti-1418	157	11	g.	g.	PROPN
dti-1418	157	12	a	a	DET
dti-1418	157	13	multicenter	multicenter	NOUN
dti-1418	157	14	,	,	PUNCT
dti-1418	157	15	open	open	ADJ
dti-1418	157	16	-	-	PUNCT
dti-1418	157	17	label	label	NOUN
dti-1418	157	18	study	study	NOUN
dti-1418	157	19	of	of	ADP
dti-1418	157	20	vernakalant	vernakalant	NOUN
dti-1418	157	21	for	for	ADP
dti-1418	157	22	the	the	DET
dti-1418	157	23	conversion	conversion	NOUN
dti-1418	157	24	of	of	ADP
dti-1418	157	25	atrial	atrial	ADJ
dti-1418	157	26	fibrillation	fibrillation	NOUN
dti-1418	157	27	to	to	ADP
dti-1418	157	28	sinus	sinus	NOUN
dti-1418	157	29	rhythm	rhythm	NOUN
dti-1418	157	30	.	.	PUNCT
dti-1418	158	1	am	be	AUX
dti-1418	158	2	heart	heart	NOUN
dti-1418	158	3	j.	j.	PROPN
dti-1418	158	4	2010;159:1095–1101	2010;159:1095–1101	NUM
dti-1418	158	5	.	.	PUNCT
dti-1418	159	1	27	27	NUM
dti-1418	159	2	.	.	PUNCT
dti-1418	159	3	dalyanoglu	dalyanoglu	PROPN
dti-1418	159	4	h	h	PROPN
dti-1418	159	5	,	,	PUNCT
dti-1418	159	6	mehdiani	mehdiani	PROPN
dti-1418	159	7	a	a	PRON
dti-1418	159	8	,	,	PUNCT
dti-1418	159	9	minol	minol	NOUN
dti-1418	159	10	jp	jp	NOUN
dti-1418	159	11	,	,	PUNCT
dti-1418	159	12	et	et	PROPN
dti-1418	159	13	al	al	PROPN
dti-1418	159	14	.	.	PUNCT
dti-1418	159	15	conversion	conversion	NOUN
dti-1418	159	16	of	of	ADP
dti-1418	159	17	atrial	atrial	ADJ
dti-1418	159	18	fibrillation	fibrillation	NOUN
dti-1418	159	19	after	after	ADP
dti-1418	159	20	cardiosurgical	cardiosurgical	ADJ
dti-1418	159	21	procedures	procedure	NOUN
dti-1418	159	22	by	by	ADP
dti-1418	159	23	vernakalant	vernakalant	NOUN
dti-1418	159	24	as	as	ADP
dti-1418	159	25	an	an	DET
dti-1418	159	26	atrial	atrial	ADJ
dti-1418	159	27	repolarization	repolarization	NOUN
dti-1418	159	28	delaying	delay	VERB
dti-1418	159	29	agent	agent	NOUN
dti-1418	159	30	(	(	PUNCT
dti-1418	159	31	arda	arda	PROPN
dti-1418	159	32	)	)	PUNCT
dti-1418	159	33	.	.	PUNCT
dti-1418	160	1	heart	heart	NOUN
dti-1418	160	2	surg	surg	PROPN
dti-1418	160	3	forum	forum	PROPN
dti-1418	160	4	.	.	PUNCT
dti-1418	161	1	2018;21	2018;21	NUM
dti-1418	161	2	:	:	PUNCT
dti-1418	161	3	e201	e201	NUM
dti-1418	161	4	–	–	PUNCT
dti-1418	161	5	e208	e208	NUM
dti-1418	161	6	.	.	PROPN
dti-1418	161	7	28	28	NUM
dti-1418	161	8	.	.	PUNCT
dti-1418	162	1	camm	camm	PROPN
dti-1418	162	2	aj	aj	PROPN
dti-1418	162	3	,	,	PUNCT
dti-1418	162	4	capucci	capucci	VERB
dti-1418	162	5	a	a	DET
dti-1418	162	6	,	,	PUNCT
dti-1418	162	7	hohnloser	hohnloser	NOUN
dti-1418	162	8	sh	sh	PROPN
dti-1418	162	9	,	,	PUNCT
dti-1418	162	10	et	et	PROPN
dti-1418	162	11	al	al	PROPN
dti-1418	162	12	.	.	PUNCT
dti-1418	163	1	a	a	DET
dti-1418	163	2	randomized	randomized	ADJ
dti-1418	163	3	active	active	ADV
dti-1418	163	4	-	-	PUNCT
dti-1418	163	5	controlled	control	VERB
dti-1418	163	6	study	study	NOUN
dti-1418	163	7	comparing	compare	VERB
dti-1418	163	8	the	the	DET
dti-1418	163	9	efficacy	efficacy	NOUN
dti-1418	163	10	and	and	CCONJ
dti-1418	163	11	safety	safety	NOUN
dti-1418	163	12	of	of	ADP
dti-1418	163	13	vernakalant	vernakalant	NOUN
dti-1418	163	14	to	to	PART
dti-1418	163	15	amiodarone	amiodarone	VERB
dti-1418	163	16	in	in	ADP
dti-1418	163	17	recentonset	recentonset	NOUN
dti-1418	163	18	atrial	atrial	ADJ
dti-1418	163	19	fibrillation	fibrillation	NOUN
dti-1418	163	20	.	.	PUNCT
dti-1418	164	1	j	j	PROPN
dti-1418	164	2	am	be	AUX
dti-1418	164	3	coll	coll	PROPN
dti-1418	164	4	cardiol	cardiol	NOUN
dti-1418	164	5	.	.	PUNCT
dti-1418	165	1	2011;57:313–321	2011;57:313–321	NUM
dti-1418	165	2	.	.	PUNCT
dti-1418	166	1	29	29	NUM
dti-1418	166	2	.	.	PUNCT
dti-1418	167	1	conde	conde	PROPN
dti-1418	167	2	d	d	X
dti-1418	167	3	,	,	PUNCT
dti-1418	167	4	costabel	costabel	NOUN
dti-1418	167	5	jp	jp	NOUN
dti-1418	167	6	,	,	PUNCT
dti-1418	167	7	aragon	aragon	PROPN
dti-1418	167	8	m	m	PROPN
dti-1418	167	9	,	,	PUNCT
dti-1418	167	10	et	et	PROPN
dti-1418	167	11	al	al	PROPN
dti-1418	167	12	.	.	PUNCT
dti-1418	168	1	propafenone	propafenone	NOUN
dti-1418	168	2	versus	versus	ADP
dti-1418	168	3	vernakalant	vernakalant	NOUN
dti-1418	168	4	for	for	ADP
dti-1418	168	5	conversion	conversion	NOUN
dti-1418	168	6	of	of	ADP
dti-1418	168	7	recent	recent	ADJ
dti-1418	168	8	-	-	PUNCT
dti-1418	168	9	onset	onset	ADJ
dti-1418	168	10	atrial	atrial	ADJ
dti-1418	168	11	fibrillation	fibrillation	NOUN
dti-1418	168	12	.	.	PUNCT
dti-1418	169	1	cardiovasc	cardiovasc	PROPN
dti-1418	169	2	ther	ther	PROPN
dti-1418	169	3	.	.	PUNCT
dti-1418	170	1	2013;31:377–380	2013;31:377–380	ADJ
dti-1418	170	2	.	.	PUNCT
dti-1418	170	3	30	30	NUM
dti-1418	170	4	.	.	PUNCT
dti-1418	171	1	simon	simon	PROPN
dti-1418	171	2	a	a	PROPN
dti-1418	171	3	,	,	PUNCT
dti-1418	171	4	niederdoeckl	niederdoeckl	PROPN
dti-1418	171	5	j	j	PROPN
dti-1418	171	6	,	,	PUNCT
dti-1418	171	7	skyllouriotis	skyllouriotis	PROPN
dti-1418	171	8	e	e	NOUN
dti-1418	171	9	,	,	PUNCT
dti-1418	172	1	et	et	PROPN
dti-1418	172	2	al	al	PROPN
dti-1418	172	3	.	.	PROPN
dti-1418	172	4	vernakalant	vernakalant	NOUN
dti-1418	172	5	is	be	AUX
dti-1418	172	6	superior	superior	ADJ
dti-1418	172	7	to	to	PART
dti-1418	172	8	ibutilide	ibutilide	VERB
dti-1418	172	9	for	for	ADP
dti-1418	172	10	achieving	achieve	VERB
dti-1418	172	11	sinus	sinus	NOUN
dti-1418	172	12	rhythm	rhythm	NOUN
dti-1418	172	13	in	in	ADP
dti-1418	172	14	patients	patient	NOUN
dti-1418	172	15	with	with	ADP
dti-1418	172	16	recent	recent	ADJ
dti-1418	172	17	-	-	PUNCT
dti-1418	172	18	onset	onset	ADJ
dti-1418	172	19	atrial	atrial	ADJ
dti-1418	172	20	fibrillation	fibrillation	NOUN
dti-1418	172	21	:	:	PUNCT
dti-1418	172	22	a	a	DET
dti-1418	172	23	randomized	randomized	ADJ
dti-1418	172	24	controlled	control	VERB
dti-1418	172	25	trial	trial	NOUN
dti-1418	172	26	at	at	ADP
dti-1418	172	27	the	the	DET
dti-1418	172	28	emergency	emergency	NOUN
dti-1418	172	29	department	department	PROPN
dti-1418	172	30	.	.	PUNCT
dti-1418	173	1	europace	europace	NOUN
dti-1418	173	2	.	.	PUNCT
dti-1418	174	1	2017;19	2017;19	NOUN
dti-1418	174	2	:	:	PUNCT
dti-1418	175	1	233–240	233–240	NUM
dti-1418	175	2	.	.	NOUN
dti-1418	176	1	31	31	NUM
dti-1418	176	2	.	.	PUNCT
dti-1418	177	1	carbajosa	carbajosa	PROPN
dti-1418	177	2	dalmau	dalmau	PROPN
dti-1418	177	3	j	j	PROPN
dti-1418	177	4	,	,	PUNCT
dti-1418	177	5	cosin	cosin	PROPN
dti-1418	177	6	-	-	PUNCT
dti-1418	177	7	sales	sales	PROPN
dti-1418	177	8	j	j	PROPN
dti-1418	177	9	,	,	PUNCT
dti-1418	177	10	perez	perez	PROPN
dti-1418	177	11	-	-	PUNCT
dti-1418	177	12	dura	dura	PROPN
dti-1418	177	13	mj	mj	PROPN
dti-1418	177	14	,	,	PUNCT
dti-1418	177	15	et	et	PROPN
dti-1418	177	16	al	al	PROPN
dti-1418	177	17	.	.	PROPN
dti-1418	177	18	vernakalant	vernakalant	PROPN
dti-1418	177	19	in	in	ADP
dti-1418	177	20	hospital	hospital	NOUN
dti-1418	177	21	emergency	emergency	NOUN
dti-1418	177	22	practice	practice	NOUN
dti-1418	177	23	:	:	PUNCT
dti-1418	177	24	safety	safety	NOUN
dti-1418	177	25	and	and	CCONJ
dti-1418	177	26	effectiveness	effectiveness	NOUN
dti-1418	177	27	.	.	PUNCT
dti-1418	178	1	emergencias	emergencias	PROPN
dti-1418	178	2	.	.	PUNCT
dti-1418	179	1	2017;29	2017;29	NUM
dti-1418	179	2	:	:	PUNCT
dti-1418	179	3	397–402	397–402	NUM
dti-1418	179	4	.	.	NOUN
dti-1418	179	5	32	32	NUM
dti-1418	179	6	.	.	PUNCT
dti-1418	179	7	akel	akel	PROPN
dti-1418	179	8	t	t	PROPN
dti-1418	179	9	,	,	PUNCT
dti-1418	179	10	lafferty	lafferty	PROPN
dti-1418	179	11	j.	j.	PROPN
dti-1418	179	12	efficacy	efficacy	PROPN
dti-1418	179	13	and	and	CCONJ
dti-1418	179	14	safety	safety	NOUN
dti-1418	179	15	of	of	ADP
dti-1418	179	16	intravenous	intravenous	ADJ
dti-1418	179	17	vernakalant	vernakalant	NOUN
dti-1418	179	18	for	for	ADP
dti-1418	179	19	the	the	DET
dti-1418	179	20	rapid	rapid	ADJ
dti-1418	179	21	conversion	conversion	NOUN
dti-1418	179	22	of	of	ADP
dti-1418	179	23	recent	recent	ADJ
dti-1418	179	24	-	-	PUNCT
dti-1418	179	25	onset	onset	ADJ
dti-1418	179	26	atrial	atrial	ADJ
dti-1418	179	27	fibrillation	fibrillation	NOUN
dti-1418	179	28	:	:	PUNCT
dti-1418	179	29	a	a	DET
dti-1418	179	30	meta	meta	ADJ
dti-1418	179	31	-	-	PUNCT
dti-1418	179	32	analysis	analysis	NOUN
dti-1418	179	33	.	.	PUNCT
dti-1418	180	1	ann	ann	PROPN
dti-1418	180	2	noninvasive	noninvasive	PROPN
dti-1418	180	3	electrocardiol	electrocardiol	PROPN
dti-1418	180	4	.	.	PUNCT
dti-1418	181	1	2018;23	2018;23	NUM
dti-1418	181	2	:	:	PUNCT
dti-1418	181	3	e12508	e12508	NOUN
dti-1418	181	4	.	.	NOUN
dti-1418	182	1	33	33	NUM
dti-1418	182	2	.	.	PUNCT
dti-1418	183	1	pohjantähti	pohjantähti	NOUN
dti-1418	183	2	-	-	PUNCT
dti-1418	183	3	maaroos	maaroos	PROPN
dti-1418	183	4	h	h	NOUN
dti-1418	183	5	,	,	PUNCT
dti-1418	183	6	hyppola	hyppola	PROPN
dti-1418	183	7	h	h	NOUN
dti-1418	183	8	,	,	PUNCT
dti-1418	183	9	lekkala	lekkala	PROPN
dti-1418	183	10	m	m	PROPN
dti-1418	183	11	,	,	PUNCT
dti-1418	183	12	sinisalo	sinisalo	PROPN
dti-1418	183	13	e	e	NOUN
dti-1418	183	14	,	,	PUNCT
dti-1418	183	15	heikkola	heikkola	PROPN
dti-1418	183	16	a	a	PRON
dti-1418	183	17	,	,	PUNCT
dti-1418	183	18	hartikainen	hartikainen	PROPN
dti-1418	183	19	j.	j.	PROPN
dti-1418	183	20	intravenous	intravenous	PROPN
dti-1418	183	21	vernakalant	vernakalant	NOUN
dti-1418	183	22	in	in	ADP
dti-1418	183	23	comparison	comparison	NOUN
dti-1418	183	24	with	with	ADP
dti-1418	183	25	intravenous	intravenous	ADJ
dti-1418	183	26	flecainide	flecainide	NOUN
dti-1418	183	27	in	in	ADP
dti-1418	183	28	the	the	DET
dti-1418	183	29	cardioversion	cardioversion	NOUN
dti-1418	183	30	of	of	ADP
dti-1418	183	31	recent	recent	ADJ
dti-1418	183	32	-	-	PUNCT
dti-1418	183	33	onset	onset	ADJ
dti-1418	183	34	atrial	atrial	ADJ
dti-1418	183	35	fibrillation	fibrillation	NOUN
dti-1418	183	36	.	.	PUNCT
dti-1418	184	1	eur	eur	PROPN
dti-1418	184	2	heart	heart	PROPN
dti-1418	184	3	j	j	PROPN
dti-1418	184	4	acute	acute	PROPN
dti-1418	184	5	cardiovasc	cardiovasc	PROPN
dti-1418	184	6	care	care	VERB
dti-1418	184	7	.	.	PUNCT
dti-1418	185	1	2019;8:114–120	2019;8:114–120	NUM
dti-1418	185	2	.	.	PUNCT
dti-1418	186	1	34	34	NUM
dti-1418	186	2	.	.	PUNCT
dti-1418	187	1	camm	camm	PROPN
dti-1418	187	2	aj	aj	PROPN
dti-1418	187	3	,	,	PUNCT
dti-1418	187	4	lip	lip	PROPN
dti-1418	187	5	gy	gy	PROPN
dti-1418	187	6	,	,	PUNCT
dti-1418	187	7	de	de	PROPN
dti-1418	187	8	caterina	caterina	PROPN
dti-1418	187	9	r	r	PROPN
dti-1418	187	10	,	,	PUNCT
dti-1418	187	11	et	et	PROPN
dti-1418	187	12	al	al	PROPN
dti-1418	187	13	.	.	PROPN
dti-1418	187	14	2012	2012	NUM
dti-1418	187	15	focused	focus	VERB
dti-1418	187	16	update	update	NOUN
dti-1418	187	17	of	of	ADP
dti-1418	187	18	the	the	DET
dti-1418	187	19	esc	esc	NOUN
dti-1418	187	20	guidelines	guideline	NOUN
dti-1418	187	21	for	for	ADP
dti-1418	187	22	the	the	DET
dti-1418	187	23	management	management	NOUN
dti-1418	187	24	of	of	ADP
dti-1418	187	25	atrial	atrial	ADJ
dti-1418	187	26	fibrillation	fibrillation	NOUN
dti-1418	187	27	:	:	PUNCT
dti-1418	187	28	an	an	DET
dti-1418	187	29	update	update	NOUN
dti-1418	187	30	of	of	ADP
dti-1418	187	31	the	the	DET
dti-1418	187	32	2010	2010	NUM
dti-1418	187	33	esc	esc	NOUN
dti-1418	187	34	guidelines	guideline	NOUN
dti-1418	187	35	for	for	ADP
dti-1418	187	36	the	the	DET
dti-1418	187	37	management	management	NOUN
dti-1418	187	38	of	of	ADP
dti-1418	187	39	atrial	atrial	ADJ
dti-1418	187	40	fibrillation	fibrillation	NOUN
dti-1418	187	41	.	.	PUNCT
dti-1418	188	1	developed	develop	VERB
dti-1418	188	2	with	with	ADP
dti-1418	188	3	the	the	DET
dti-1418	188	4	special	special	ADJ
dti-1418	188	5	contribution	contribution	NOUN
dti-1418	188	6	of	of	ADP
dti-1418	188	7	the	the	DET
dti-1418	188	8	european	european	ADJ
dti-1418	188	9	heart	heart	PROPN
dti-1418	188	10	rhythm	rhythm	PROPN
dti-1418	188	11	association	association	PROPN
dti-1418	188	12	.	.	PUNCT
dti-1418	189	1	eur	eur	PROPN
dti-1418	189	2	heart	heart	NOUN
dti-1418	189	3	j.	j.	PROPN
dti-1418	189	4	2012;33:2719–2747	2012;33:2719–2747	PROPN
dti-1418	189	5	.	.	PROPN
dti-1418	189	6	35	35	NUM
dti-1418	189	7	.	.	PUNCT
dti-1418	190	1	vogiatzis	vogiatzis	PROPN
dti-1418	190	2	i	i	PRON
dti-1418	190	3	,	,	PUNCT
dti-1418	190	4	papavasiliou	papavasiliou	NOUN
dti-1418	190	5	e	e	NOUN
dti-1418	190	6	,	,	PUNCT
dti-1418	190	7	dapcevitch	dapcevitch	VERB
dti-1418	190	8	i	i	PRON
dti-1418	190	9	,	,	PUNCT
dti-1418	190	10	pittas	pittas	PROPN
dti-1418	190	11	s	s	PROPN
dti-1418	190	12	,	,	PUNCT
dti-1418	190	13	koulouris	koulouris	PROPN
dti-1418	190	14	e.	e.	PROPN
dti-1418	190	15	vernakalant	vernakalant	PROPN
dti-1418	190	16	versus	versus	ADP
dti-1418	190	17	ibutilide	ibutilide	NOUN
dti-1418	190	18	for	for	ADP
dti-1418	190	19	immediate	immediate	ADJ
dti-1418	190	20	conversion	conversion	NOUN
dti-1418	190	21	of	of	ADP
dti-1418	190	22	recent	recent	ADJ
dti-1418	190	23	-	-	PUNCT
dti-1418	190	24	onset	onset	ADJ
dti-1418	190	25	atrial	atrial	ADJ
dti-1418	190	26	fibrillation	fibrillation	NOUN
dti-1418	190	27	.	.	PUNCT
dti-1418	191	1	hippokratia	hippokratia	NOUN
dti-1418	191	2	.	.	PUNCT
dti-1418	192	1	2017;21:67–73	2017;21:67–73	X
dti-1418	192	2	.	.	X
dti-1418	192	3	36	36	NUM
dti-1418	192	4	.	.	PUNCT
dti-1418	192	5	bash	bash	PROPN
dti-1418	192	6	ld	ld	PROPN
dti-1418	192	7	,	,	PUNCT
dti-1418	192	8	buono	buono	PROPN
dti-1418	192	9	jl	jl	PROPN
dti-1418	192	10	,	,	PUNCT
dti-1418	192	11	davies	davies	PROPN
dti-1418	192	12	gm	gm	PROPN
dti-1418	192	13	,	,	PUNCT
dti-1418	192	14	et	et	PROPN
dti-1418	192	15	al	al	PROPN
dti-1418	192	16	.	.	PUNCT
dti-1418	192	17	systematic	systematic	PROPN
dti-1418	192	18	review	review	NOUN
dti-1418	192	19	and	and	CCONJ
dti-1418	192	20	meta	meta	NOUN
dti-1418	192	21	-	-	PUNCT
dti-1418	192	22	analysis	analysis	NOUN
dti-1418	192	23	of	of	ADP
dti-1418	192	24	the	the	DET
dti-1418	192	25	efficacy	efficacy	NOUN
dti-1418	192	26	of	of	ADP
dti-1418	192	27	cardioversion	cardioversion	NOUN
dti-1418	192	28	by	by	ADP
dti-1418	192	29	vernakalant	vernakalant	NOUN
dti-1418	192	30	and	and	CCONJ
dti-1418	192	31	comparators	comparator	NOUN
dti-1418	192	32	in	in	ADP
dti-1418	192	33	patients	patient	NOUN
dti-1418	192	34	with	with	ADP
dti-1418	192	35	atrial	atrial	ADJ
dti-1418	192	36	fibrillation	fibrillation	NOUN
dti-1418	192	37	.	.	PUNCT
dti-1418	193	1	cardiovasc	cardiovasc	PROPN
dti-1418	193	2	drugs	drug	VERB
dti-1418	193	3	ther	ther	ADV
dti-1418	193	4	.	.	PUNCT
dti-1418	194	1	2012;26:167–179	2012;26:167–179	NOUN
dti-1418	194	2	.	.	PUNCT
dti-1418	195	1	37	37	NUM
dti-1418	195	2	.	.	PUNCT
dti-1418	196	1	conde	conde	PROPN
dti-1418	196	2	d	d	X
dti-1418	196	3	,	,	PUNCT
dti-1418	196	4	costabel	costabel	NOUN
dti-1418	196	5	jp	jp	NOUN
dti-1418	196	6	,	,	PUNCT
dti-1418	196	7	caro	caro	PROPN
dti-1418	196	8	m	m	PROPN
dti-1418	196	9	,	,	PUNCT
dti-1418	196	10	et	et	PROPN
dti-1418	196	11	al	al	PROPN
dti-1418	196	12	.	.	PROPN
dti-1418	196	13	flecainide	flecainide	PROPN
dti-1418	196	14	versus	versus	ADP
dti-1418	196	15	vernakalant	vernakalant	NOUN
dti-1418	196	16	for	for	ADP
dti-1418	196	17	conversion	conversion	NOUN
dti-1418	196	18	of	of	ADP
dti-1418	196	19	recent	recent	ADJ
dti-1418	196	20	-	-	PUNCT
dti-1418	196	21	onset	onset	ADJ
dti-1418	196	22	atrial	atrial	ADJ
dti-1418	196	23	fibrillation	fibrillation	NOUN
dti-1418	196	24	.	.	PUNCT
dti-1418	197	1	int	int	NOUN
dti-1418	197	2	j	j	PROPN
dti-1418	197	3	cardiol	cardiol	NOUN
dti-1418	197	4	.	.	PUNCT
dti-1418	198	1	2013;168:2423–2425	2013;168:2423–2425	X
dti-1418	198	2	.	.	X
dti-1418	199	1	https://orcid.org/0000-0002-7104-1323	https://orcid.org/0000-0002-7104-1323	PROPN
dti-1418	199	2	kossaify	kossaify	VERB
dti-1418	199	3	7	7	NUM
dti-1418	199	4	38	38	NUM
dti-1418	199	5	.	.	PUNCT
dti-1418	200	1	guerra	guerra	PROPN
dti-1418	200	2	f	f	PROPN
dti-1418	200	3	,	,	PUNCT
dti-1418	200	4	matassini	matassini	PROPN
dti-1418	200	5	mv	mv	PROPN
dti-1418	200	6	,	,	PUNCT
dti-1418	200	7	scappini	scappini	NOUN
dti-1418	200	8	l	l	PROPN
dti-1418	200	9	,	,	PUNCT
dti-1418	200	10	urbinati	urbinati	PROPN
dti-1418	200	11	a	a	PRON
dti-1418	200	12	,	,	PUNCT
dti-1418	200	13	capucci	capucci	NOUN
dti-1418	200	14	a.	a.	NOUN
dti-1418	200	15	intravenous	intravenous	ADJ
dti-1418	200	16	vernakalant	vernakalant	NOUN
dti-1418	200	17	for	for	ADP
dti-1418	200	18	the	the	DET
dti-1418	200	19	rapid	rapid	ADJ
dti-1418	200	20	conversion	conversion	NOUN
dti-1418	200	21	of	of	ADP
dti-1418	200	22	recent	recent	ADJ
dti-1418	200	23	onset	onset	VERB
dti-1418	200	24	atrial	atrial	ADJ
dti-1418	200	25	fibrillation	fibrillation	NOUN
dti-1418	200	26	:	:	PUNCT
dti-1418	200	27	systematic	systematic	ADJ
dti-1418	200	28	review	review	NOUN
dti-1418	200	29	and	and	CCONJ
dti-1418	200	30	meta	meta	ADJ
dti-1418	200	31	-	-	PUNCT
dti-1418	200	32	analysis	analysis	NOUN
dti-1418	200	33	.	.	PUNCT
dti-1418	201	1	expert	expert	NOUN
dti-1418	201	2	rev	rev	PROPN
dti-1418	201	3	cardiovasc	cardiovasc	PROPN
dti-1418	201	4	ther	ther	PROPN
dti-1418	201	5	.	.	PUNCT
dti-1418	202	1	2014;12:1067–1075	2014;12:1067–1075	ADJ
dti-1418	202	2	.	.	PROPN
dti-1418	203	1	39	39	NUM
dti-1418	203	2	.	.	PUNCT
dti-1418	204	1	de	de	X
dti-1418	204	2	riva	riva	PROPN
dti-1418	204	3	-	-	PUNCT
dti-1418	204	4	silva	silva	PROPN
dti-1418	204	5	m	m	PROPN
dti-1418	204	6	,	,	PUNCT
dti-1418	204	7	montero	montero	PROPN
dti-1418	204	8	-	-	PUNCT
dti-1418	204	9	cabezas	cabezas	PROPN
dti-1418	204	10	jm	jm	PROPN
dti-1418	204	11	,	,	PUNCT
dti-1418	204	12	salgado	salgado	PROPN
dti-1418	204	13	-	-	ADJ
dti-1418	204	14	aranda	aranda	PROPN
dti-1418	204	15	r	r	NOUN
dti-1418	204	16	,	,	PUNCT
dti-1418	204	17	lopez	lopez	NOUN
dti-1418	204	18	-	-	PUNCT
dti-1418	204	19	gil	gil	PROPN
dti-1418	204	20	m	m	PROPN
dti-1418	204	21	,	,	PUNCT
dti-1418	204	22	fontenla	fontenla	NOUN
dti-1418	204	23	-	-	PUNCT
dti-1418	204	24	cerezuela	cerezuela	NOUN
dti-1418	204	25	a	a	PRON
dti-1418	204	26	,	,	PUNCT
dti-1418	204	27	arribas	arribas	PROPN
dti-1418	204	28	-	-	PUNCT
dti-1418	204	29	ynsaurriaga	ynsaurriaga	PROPN
dti-1418	204	30	f.	f.	PROPN
dti-1418	204	31	1:1	1:1	NUM
dti-1418	204	32	atrial	atrial	ADJ
dti-1418	204	33	flutter	flutter	NOUN
dti-1418	204	34	after	after	ADP
dti-1418	204	35	vernakalant	vernakalant	NOUN
dti-1418	204	36	administration	administration	NOUN
dti-1418	204	37	for	for	ADP
dti-1418	204	38	atrial	atrial	ADJ
dti-1418	204	39	fibrillation	fibrillation	NOUN
dti-1418	204	40	cardioversion	cardioversion	NOUN
dti-1418	204	41	.	.	PUNCT
dti-1418	205	1	rev	rev	PROPN
dti-1418	205	2	esp	esp	ADJ
dti-1418	205	3	cardiol	cardiol	NOUN
dti-1418	205	4	(	(	PUNCT
dti-1418	205	5	engl	engl	PROPN
dti-1418	205	6	ed	ed	NOUN
dti-1418	205	7	)	)	PUNCT
dti-1418	205	8	.	.	PUNCT
dti-1418	206	1	2012;65:1062–1064	2012;65:1062–1064	NUM
dti-1418	206	2	.	.	PUNCT
dti-1418	207	1	40	40	NUM
dti-1418	207	2	.	.	PUNCT
dti-1418	208	1	camm	camm	PROPN
dti-1418	208	2	aj	aj	PROPN
dti-1418	208	3	,	,	PUNCT
dti-1418	208	4	toft	toft	PROPN
dti-1418	208	5	e	e	NOUN
dti-1418	208	6	,	,	PUNCT
dti-1418	208	7	torp	torp	PROPN
dti-1418	208	8	-	-	PROPN
dti-1418	208	9	pedersen	pedersen	PROPN
dti-1418	208	10	c	c	PROPN
dti-1418	208	11	,	,	PUNCT
dti-1418	208	12	et	et	PROPN
dti-1418	208	13	al	al	PROPN
dti-1418	208	14	.	.	PROPN
dti-1418	208	15	efficacy	efficacy	NOUN
dti-1418	208	16	and	and	CCONJ
dti-1418	208	17	safety	safety	NOUN
dti-1418	208	18	of	of	ADP
dti-1418	208	19	vernakalant	vernakalant	NOUN
dti-1418	208	20	in	in	ADP
dti-1418	208	21	patients	patient	NOUN
dti-1418	208	22	with	with	ADP
dti-1418	208	23	atrial	atrial	ADJ
dti-1418	208	24	flutter	flutter	NOUN
dti-1418	208	25	:	:	PUNCT
dti-1418	208	26	a	a	DET
dti-1418	208	27	randomized	randomized	ADJ
dti-1418	208	28	,	,	PUNCT
dti-1418	208	29	double	double	ADJ
dti-1418	208	30	-	-	PUNCT
dti-1418	208	31	blind	blind	ADJ
dti-1418	208	32	,	,	PUNCT
dti-1418	208	33	placebo	placebo	NOUN
dti-1418	208	34	-	-	PUNCT
dti-1418	208	35	controlled	control	VERB
dti-1418	208	36	trial	trial	NOUN
dti-1418	208	37	.	.	PUNCT
dti-1418	208	38	europace	europace	NOUN
dti-1418	208	39	.	.	PUNCT
dti-1418	209	1	2012;14:804–809	2012;14:804–809	NOUN
dti-1418	209	2	.	.	PUNCT
dti-1418	210	1	41	41	NUM
dti-1418	210	2	.	.	X
dti-1418	211	1	torp	torp	PROPN
dti-1418	211	2	-	-	PROPN
dti-1418	211	3	pedersen	pedersen	PROPN
dti-1418	211	4	c	c	PROPN
dti-1418	211	5	,	,	PUNCT
dti-1418	211	6	raev	raev	PROPN
dti-1418	211	7	dh	dh	PROPN
dti-1418	211	8	,	,	PUNCT
dti-1418	211	9	dickinson	dickinson	PROPN
dti-1418	211	10	g	g	PROPN
dti-1418	211	11	,	,	PUNCT
dti-1418	211	12	butterfield	butterfield	PROPN
dti-1418	211	13	nn	nn	PROPN
dti-1418	211	14	,	,	PUNCT
dti-1418	211	15	mangal	mangal	PROPN
dti-1418	211	16	b	b	PROPN
dti-1418	211	17	,	,	PUNCT
dti-1418	211	18	beatch	beatch	PROPN
dti-1418	211	19	gn	gn	PROPN
dti-1418	211	20	.	.	PROPN
dti-1418	212	1	a	a	DET
dti-1418	212	2	randomized	randomized	ADJ
dti-1418	212	3	,	,	PUNCT
dti-1418	212	4	placebo	placebo	NOUN
dti-1418	212	5	-	-	PUNCT
dti-1418	212	6	controlled	control	VERB
dti-1418	212	7	study	study	NOUN
dti-1418	212	8	of	of	ADP
dti-1418	212	9	vernakalant	vernakalant	NOUN
dti-1418	212	10	(	(	PUNCT
dti-1418	212	11	oral	oral	ADJ
dti-1418	212	12	)	)	PUNCT
dti-1418	212	13	for	for	ADP
dti-1418	212	14	the	the	DET
dti-1418	212	15	prevention	prevention	NOUN
dti-1418	212	16	of	of	ADP
dti-1418	212	17	atrial	atrial	ADJ
dti-1418	212	18	fibrillation	fibrillation	NOUN
dti-1418	212	19	recurrence	recurrence	NOUN
dti-1418	212	20	after	after	ADP
dti-1418	212	21	cardioversion	cardioversion	NOUN
dti-1418	212	22	.	.	PUNCT
dti-1418	213	1	circ	circ	PROPN
dti-1418	213	2	arrhythm	arrhythm	PROPN
dti-1418	213	3	electrophysiol	electrophysiol	PROPN
dti-1418	213	4	.	.	PUNCT
dti-1418	214	1	2011;4:637–643	2011;4:637–643	NUM
dti-1418	214	2	.	.	PUNCT
dti-1418	215	1	42	42	NUM
dti-1418	215	2	.	.	PUNCT
dti-1418	216	1	yan	yan	PROPN
dti-1418	216	2	h	h	PROPN
dti-1418	216	3	,	,	PUNCT
dti-1418	216	4	aung	aung	PROPN
dti-1418	216	5	tt	tt	PROPN
dti-1418	216	6	,	,	PUNCT
dti-1418	216	7	guoqiang	guoqiang	PROPN
dti-1418	216	8	z	z	PROPN
dti-1418	216	9	,	,	PUNCT
dti-1418	216	10	zhengnan	zhengnan	PROPN
dti-1418	216	11	z	z	PROPN
dti-1418	216	12	,	,	PUNCT
dti-1418	216	13	lan	lan	PROPN
dti-1418	216	14	j	j	PROPN
dti-1418	216	15	,	,	PUNCT
dti-1418	216	16	zhiyu	zhiyu	PROPN
dti-1418	216	17	z.	z.	PROPN
dti-1418	217	1	meta	meta	VERB
dti-1418	217	2	-	-	PUNCT
dti-1418	217	3	analysis	analysis	NOUN
dti-1418	217	4	of	of	ADP
dti-1418	217	5	effect	effect	NOUN
dti-1418	217	6	of	of	ADP
dti-1418	217	7	vernakalant	vernakalant	NOUN
dti-1418	217	8	on	on	ADP
dti-1418	217	9	conversion	conversion	NOUN
dti-1418	217	10	of	of	ADP
dti-1418	217	11	atrial	atrial	ADJ
dti-1418	217	12	fibrillation	fibrillation	NOUN
dti-1418	217	13	.	.	PUNCT
dti-1418	218	1	bmc	bmc	ADJ
dti-1418	218	2	res	re	NOUN
dti-1418	218	3	notes	note	NOUN
dti-1418	218	4	.	.	PUNCT
dti-1418	219	1	2013;6:94	2013;6:94	NOUN
dti-1418	219	2	.	.	PUNCT
dti-1418	220	1	43	43	NUM
dti-1418	220	2	.	.	PUNCT
dti-1418	221	1	costabel	costabel	NOUN
dti-1418	221	2	jp	jp	PROPN
dti-1418	221	3	,	,	PUNCT
dti-1418	221	4	lambardi	lambardi	PROPN
dti-1418	221	5	f	f	PROPN
dti-1418	221	6	,	,	PUNCT
dti-1418	221	7	aragon	aragon	PROPN
dti-1418	221	8	m	m	PROPN
dti-1418	221	9	,	,	PUNCT
dti-1418	221	10	et	et	PROPN
dti-1418	221	11	al	al	PROPN
dti-1418	221	12	.	.	PUNCT
dti-1418	221	13	predictors	predictor	NOUN
dti-1418	221	14	of	of	ADP
dti-1418	221	15	conversion	conversion	NOUN
dti-1418	221	16	of	of	ADP
dti-1418	221	17	recentonset	recentonset	NOUN
dti-1418	221	18	atrial	atrial	ADJ
dti-1418	221	19	fibrillation	fibrillation	NOUN
dti-1418	221	20	treated	treat	VERB
dti-1418	221	21	with	with	ADP
dti-1418	221	22	vernakalant	vernakalant	NOUN
dti-1418	221	23	.	.	PUNCT
dti-1418	222	1	pacing	pace	VERB
dti-1418	222	2	clin	clin	PROPN
dti-1418	222	3	electrophysiol	electrophysiol	NOUN
dti-1418	222	4	.	.	PUNCT
dti-1418	223	1	2015;38:196–200	2015;38:196–200	PROPN
dti-1418	223	2	.	.	PUNCT
dti-1418	224	1	44	44	NUM
dti-1418	224	2	.	.	PUNCT
dti-1418	225	1	manolis	manolis	PROPN
dti-1418	225	2	as	as	ADP
dti-1418	225	3	,	,	PUNCT
dti-1418	225	4	bethanis	bethanis	PROPN
dti-1418	225	5	s	s	PART
dti-1418	225	6	,	,	PUNCT
dti-1418	225	7	metaxa	metaxa	PROPN
dti-1418	225	8	s	s	NOUN
dti-1418	225	9	,	,	PUNCT
dti-1418	225	10	polytarchou	polytarchou	PROPN
dti-1418	225	11	k	k	NOUN
dti-1418	225	12	,	,	PUNCT
dti-1418	225	13	sakellaris	sakellaris	PROPN
dti-1418	225	14	n	n	CCONJ
dti-1418	225	15	,	,	PUNCT
dti-1418	225	16	pyrros	pyrros	PROPN
dti-1418	225	17	i.	i.	NOUN
dti-1418	225	18	use	use	NOUN
dti-1418	225	19	of	of	ADP
dti-1418	225	20	intravenous	intravenous	ADJ
dti-1418	225	21	vernakalant	vernakalant	NOUN
dti-1418	225	22	for	for	ADP
dti-1418	225	23	atrial	atrial	ADJ
dti-1418	225	24	fibrillation	fibrillation	NOUN
dti-1418	225	25	conversion	conversion	NOUN
dti-1418	225	26	in	in	ADP
dti-1418	225	27	the	the	DET
dti-1418	225	28	regular	regular	ADJ
dti-1418	225	29	ward	ward	NOUN
dti-1418	225	30	under	under	ADP
dti-1418	225	31	only	only	ADJ
dti-1418	225	32	bedside	bedside	NOUN
dti-1418	225	33	monitoring	monitoring	NOUN
dti-1418	225	34	.	.	PUNCT
dti-1418	226	1	hellenic	hellenic	PROPN
dti-1418	226	2	j	j	PROPN
dti-1418	226	3	cardiol	cardiol	NOUN
dti-1418	226	4	.	.	PUNCT
dti-1418	227	1	epub	epub	NOUN
dti-1418	227	2	ahead	ahead	ADV
dti-1418	227	3	of	of	ADP
dti-1418	227	4	print	print	NOUN
dti-1418	227	5	15	15	NUM
dti-1418	227	6	february	february	NOUN
dti-1418	227	7	2018	2018	NUM
dti-1418	227	8	.	.	PUNCT
dti-1418	228	1	doi:10.1016	doi:10.1016	PROPN
dti-1418	228	2	/	/	SYM
dti-1418	228	3	j.hjc.2018.02.003	j.hjc.2018.02.003	PROPN
dti-1418	228	4	.	.	PROPN
dti-1418	228	5	45	45	NUM
dti-1418	228	6	.	.	PUNCT
dti-1418	228	7	arrigo	arrigo	PROPN
dti-1418	228	8	m	m	PROPN
dti-1418	228	9	,	,	PUNCT
dti-1418	228	10	bettex	bettex	NOUN
dti-1418	228	11	d	d	PROPN
dti-1418	228	12	,	,	PUNCT
dti-1418	228	13	rudiger	rudiger	NOUN
dti-1418	228	14	a.	a.	NOUN
dti-1418	228	15	treatment	treatment	NOUN
dti-1418	228	16	of	of	ADP
dti-1418	228	17	atrial	atrial	ADJ
dti-1418	228	18	fibrillation	fibrillation	NOUN
dti-1418	228	19	in	in	ADP
dti-1418	228	20	intensive	intensive	ADJ
dti-1418	228	21	care	care	NOUN
dti-1418	228	22	units	unit	NOUN
dti-1418	228	23	and	and	CCONJ
dti-1418	228	24	emergency	emergency	NOUN
dti-1418	228	25	departments	department	NOUN
dti-1418	228	26	.	.	PUNCT
dti-1418	229	1	med	med	PROPN
dti-1418	229	2	klin	klin	PROPN
dti-1418	229	3	intensivmed	intensivme	VERB
dti-1418	229	4	notfmed	notfme	VERB
dti-1418	229	5	.	.	PUNCT
dti-1418	230	1	2015;110	2015;110	NUM
dti-1418	230	2	:	:	PUNCT
dti-1418	231	1	614–620	614–620	NUM
dti-1418	231	2	.	.	NOUN
dti-1418	232	1	46	46	NUM
dti-1418	232	2	.	.	PUNCT
dti-1418	232	3	airaksinen	airaksinen	PROPN
dti-1418	232	4	ke	ke	PROPN
dti-1418	232	5	,	,	PUNCT
dti-1418	232	6	gronberg	gronberg	PROPN
dti-1418	232	7	t	t	PROPN
dti-1418	232	8	,	,	PUNCT
dti-1418	232	9	nuotio	nuotio	PROPN
dti-1418	233	1	i	i	PROPN
dti-1418	233	2	,	,	PUNCT
dti-1418	233	3	et	et	PROPN
dti-1418	233	4	al	al	PROPN
dti-1418	233	5	.	.	PROPN
dti-1418	233	6	thromboembolic	thromboembolic	PROPN
dti-1418	233	7	complications	complication	NOUN
dti-1418	233	8	after	after	ADP
dti-1418	233	9	cardioversion	cardioversion	NOUN
dti-1418	233	10	of	of	ADP
dti-1418	233	11	acute	acute	ADJ
dti-1418	233	12	atrial	atrial	ADJ
dti-1418	233	13	fibrillation	fibrillation	NOUN
dti-1418	233	14	:	:	PUNCT
dti-1418	233	15	the	the	DET
dti-1418	233	16	fincv	fincv	ADJ
dti-1418	233	17	(	(	PUNCT
dti-1418	233	18	finnish	finnish	ADJ
dti-1418	233	19	cardioversion	cardioversion	NOUN
dti-1418	233	20	)	)	PUNCT
dti-1418	233	21	study	study	NOUN
dti-1418	233	22	.	.	PUNCT
dti-1418	234	1	j	j	PROPN
dti-1418	234	2	am	be	AUX
dti-1418	234	3	coll	coll	PROPN
dti-1418	234	4	cardiol	cardiol	NOUN
dti-1418	234	5	.	.	PUNCT
dti-1418	235	1	2013;62:1187–1192	2013;62:1187–1192	X
dti-1418	235	2	.	.	PROPN
dti-1418	236	1	47	47	NUM
dti-1418	236	2	.	.	PUNCT
dti-1418	237	1	gronberg	gronberg	PROPN
dti-1418	237	2	t	t	PROPN
dti-1418	237	3	,	,	PUNCT
dti-1418	237	4	hartikainen	hartikainen	PROPN
dti-1418	237	5	je	je	PROPN
dti-1418	237	6	,	,	PUNCT
dti-1418	237	7	nuotio	nuotio	PROPN
dti-1418	238	1	i	i	PROPN
dti-1418	238	2	,	,	PUNCT
dti-1418	238	3	biancari	biancari	PROPN
dti-1418	238	4	f	f	PROPN
dti-1418	238	5	,	,	PUNCT
dti-1418	238	6	ylitalo	ylitalo	PROPN
dti-1418	238	7	a	a	PROPN
dti-1418	238	8	,	,	PUNCT
dti-1418	238	9	airaksinen	airaksinen	PROPN
dti-1418	238	10	ke	ke	PROPN
dti-1418	238	11	.	.	PUNCT
dti-1418	239	1	anticoagulation	anticoagulation	NOUN
dti-1418	239	2	,	,	PUNCT
dti-1418	239	3	cha2ds2vasc	cha2ds2vasc	NOUN
dti-1418	239	4	score	score	NOUN
dti-1418	239	5	,	,	PUNCT
dti-1418	239	6	and	and	CCONJ
dti-1418	239	7	thromboembolic	thromboembolic	ADJ
dti-1418	239	8	risk	risk	NOUN
dti-1418	239	9	of	of	ADP
dti-1418	239	10	cardioversion	cardioversion	NOUN
dti-1418	239	11	of	of	ADP
dti-1418	239	12	acute	acute	ADJ
dti-1418	239	13	atrial	atrial	ADJ
dti-1418	239	14	fibrillation	fibrillation	NOUN
dti-1418	239	15	(	(	PUNCT
dti-1418	239	16	from	from	ADP
dti-1418	239	17	the	the	DET
dti-1418	239	18	fincv	fincv	PROPN
dti-1418	239	19	study	study	NOUN
dti-1418	239	20	)	)	PUNCT
dti-1418	239	21	.	.	PUNCT
dti-1418	240	1	am	be	AUX
dti-1418	240	2	j	j	PROPN
dti-1418	240	3	cardiol	cardiol	NOUN
dti-1418	240	4	.	.	PUNCT
dti-1418	241	1	2016;117:1294–1298	2016;117:1294–1298	NUM
dti-1418	241	2	.	.	NOUN
dti-1418	242	1	48	48	NUM
dti-1418	242	2	.	.	PUNCT
dti-1418	243	1	garg	garg	PROPN
dti-1418	243	2	a	a	PRON
dti-1418	243	3	,	,	PUNCT
dti-1418	243	4	khunger	khunger	NOUN
dti-1418	243	5	m	m	PROPN
dti-1418	243	6	,	,	PUNCT
dti-1418	243	7	seicean	seicean	PROPN
dti-1418	243	8	s	s	PROPN
dti-1418	243	9	,	,	PUNCT
dti-1418	243	10	chung	chung	PROPN
dti-1418	243	11	mk	mk	PROPN
dti-1418	243	12	,	,	PUNCT
dti-1418	243	13	tchou	tchou	PROPN
dti-1418	243	14	pj	pj	PROPN
dti-1418	243	15	.	.	PROPN
dti-1418	243	16	incidence	incidence	NOUN
dti-1418	243	17	of	of	ADP
dti-1418	243	18	thromboembolic	thromboembolic	ADJ
dti-1418	243	19	complications	complication	NOUN
dti-1418	243	20	within	within	ADP
dti-1418	243	21	30	30	NUM
dti-1418	243	22	days	day	NOUN
dti-1418	243	23	of	of	ADP
dti-1418	243	24	electrical	electrical	ADJ
dti-1418	243	25	cardioversion	cardioversion	NOUN
dti-1418	243	26	performed	perform	VERB
dti-1418	243	27	within	within	ADP
dti-1418	243	28	48	48	NUM
dti-1418	243	29	hours	hour	NOUN
dti-1418	243	30	of	of	ADP
dti-1418	243	31	atrial	atrial	ADJ
dti-1418	243	32	fibrillation	fibrillation	NOUN
dti-1418	243	33	onset	onset	NOUN
dti-1418	243	34	.	.	PUNCT
dti-1418	244	1	jacc	jacc	PROPN
dti-1418	244	2	clin	clin	PROPN
dti-1418	244	3	electrophysiol	electrophysiol	PROPN
dti-1418	244	4	.	.	PUNCT
dti-1418	245	1	2016;2	2016;2	PRON
dti-1418	245	2	:	:	PUNCT
dti-1418	245	3	487–494	487–494	NUM
dti-1418	245	4	.	.	NOUN
dti-1418	245	5	49	49	NUM
dti-1418	245	6	.	.	PUNCT
dti-1418	246	1	klein	klein	PROPN
dti-1418	246	2	al	al	PROPN
dti-1418	246	3	,	,	PUNCT
dti-1418	246	4	grimm	grimm	PROPN
dti-1418	246	5	ra	ra	PROPN
dti-1418	246	6	,	,	PUNCT
dti-1418	246	7	murray	murray	PROPN
dti-1418	246	8	rd	rd	PROPN
dti-1418	246	9	,	,	PUNCT
dti-1418	246	10	et	et	PROPN
dti-1418	246	11	al	al	PROPN
dti-1418	246	12	;	;	PUNCT
dti-1418	246	13	assessment	assessment	NOUN
dti-1418	246	14	of	of	ADP
dti-1418	246	15	cardioversion	cardioversion	NOUN
dti-1418	246	16	using	use	VERB
dti-1418	246	17	transesophageal	transesophageal	NOUN
dti-1418	246	18	echocardiography	echocardiography	NOUN
dti-1418	246	19	investigators	investigator	NOUN
dti-1418	246	20	.	.	PUNCT
dti-1418	247	1	use	use	NOUN
dti-1418	247	2	of	of	ADP
dti-1418	247	3	transesophageal	transesophageal	ADJ
dti-1418	247	4	echocardiography	echocardiography	NOUN
dti-1418	247	5	to	to	PART
dti-1418	247	6	guide	guide	VERB
dti-1418	247	7	cardioversion	cardioversion	NOUN
dti-1418	247	8	in	in	ADP
dti-1418	247	9	patients	patient	NOUN
dti-1418	247	10	with	with	ADP
dti-1418	247	11	atrial	atrial	ADJ
dti-1418	247	12	fibrillation	fibrillation	NOUN
dti-1418	247	13	.	.	PUNCT
dti-1418	248	1	n	n	CCONJ
dti-1418	248	2	engl	engl	PROPN
dti-1418	248	3	j	j	PROPN
dti-1418	248	4	med	med	PROPN
dti-1418	248	5	.	.	PUNCT
dti-1418	249	1	2001;344:1411–1420	2001;344:1411–1420	NUM
dti-1418	249	2	.	.	PUNCT
dti-1418	250	1	50	50	NUM
dti-1418	250	2	.	.	PUNCT
dti-1418	251	1	mussigbrodt	mussigbrodt	PROPN
dti-1418	251	2	a	a	PRON
dti-1418	251	3	,	,	PUNCT
dti-1418	251	4	john	john	PROPN
dti-1418	251	5	s	s	PROPN
dti-1418	251	6	,	,	PUNCT
dti-1418	251	7	kosiuk	kosiuk	PROPN
dti-1418	251	8	j	j	PROPN
dti-1418	251	9	,	,	PUNCT
dti-1418	251	10	richter	richter	PROPN
dti-1418	251	11	s	s	PROPN
dti-1418	251	12	,	,	PUNCT
dti-1418	251	13	hindricks	hindrick	VERB
dti-1418	251	14	g	g	NOUN
dti-1418	251	15	,	,	PUNCT
dti-1418	251	16	bollmann	bollmann	PROPN
dti-1418	251	17	a.	a.	PROPN
dti-1418	251	18	vernakalant	vernakalant	PROPN
dti-1418	251	19	-	-	PUNCT
dti-1418	251	20	facilitated	facilitate	VERB
dti-1418	251	21	electrical	electrical	ADJ
dti-1418	251	22	cardioversion	cardioversion	NOUN
dti-1418	251	23	:	:	PUNCT
dti-1418	251	24	comparison	comparison	NOUN
dti-1418	251	25	of	of	ADP
dti-1418	251	26	intravenous	intravenous	ADJ
dti-1418	251	27	vernakalant	vernakalant	NOUN
dti-1418	251	28	and	and	CCONJ
dti-1418	251	29	amiodarone	amiodarone	NOUN
dti-1418	251	30	for	for	ADP
dti-1418	251	31	drug	drug	NOUN
dti-1418	251	32	-	-	PUNCT
dti-1418	251	33	enhanced	enhance	VERB
dti-1418	251	34	electrical	electrical	ADJ
dti-1418	251	35	cardioversion	cardioversion	NOUN
dti-1418	251	36	of	of	ADP
dti-1418	251	37	atrial	atrial	ADJ
dti-1418	251	38	fibrillation	fibrillation	NOUN
dti-1418	251	39	after	after	SCONJ
dti-1418	251	40	failed	fail	VERB
dti-1418	251	41	electrical	electrical	ADJ
dti-1418	251	42	cardioversion	cardioversion	NOUN
dti-1418	251	43	.	.	PUNCT
dti-1418	252	1	europace	europace	NOUN
dti-1418	252	2	.	.	PUNCT
dti-1418	253	1	2016;18:51–56	2016;18:51–56	NUM
dti-1418	253	2	.	.	X
dti-1418	254	1	51	51	NUM
dti-1418	254	2	.	.	PUNCT
dti-1418	255	1	chen	chen	PROPN
dti-1418	255	2	s	s	PROPN
dti-1418	255	3	,	,	PUNCT
dti-1418	255	4	liu	liu	PROPN
dti-1418	255	5	s	s	PROPN
dti-1418	255	6	,	,	PUNCT
dti-1418	255	7	purerfellner	purerfellner	PROPN
dti-1418	255	8	h.	h.	PROPN
dti-1418	255	9	vernakalant	vernakalant	NOUN
dti-1418	255	10	as	as	ADP
dti-1418	255	11	a	a	DET
dti-1418	255	12	novel	novel	ADJ
dti-1418	255	13	anti	anti	ADJ
dti-1418	255	14	-	-	ADJ
dti-1418	255	15	arrhythmic	arrhythmic	ADJ
dti-1418	255	16	agent	agent	NOUN
dti-1418	255	17	for	for	ADP
dti-1418	255	18	converting	convert	VERB
dti-1418	255	19	of	of	ADP
dti-1418	255	20	atrial	atrial	ADJ
dti-1418	255	21	fibrillation	fibrillation	NOUN
dti-1418	255	22	,	,	PUNCT
dti-1418	255	23	molecular	molecular	ADJ
dti-1418	255	24	mechanism	mechanism	NOUN
dti-1418	255	25	,	,	PUNCT
dti-1418	255	26	updated	update	VERB
dti-1418	255	27	clinical	clinical	ADJ
dti-1418	255	28	efficacy	efficacy	NOUN
dti-1418	255	29	,	,	PUNCT
dti-1418	255	30	and	and	CCONJ
dti-1418	255	31	future	future	ADJ
dti-1418	255	32	development	development	NOUN
dti-1418	255	33	.	.	PUNCT
dti-1418	256	1	curr	curr	PROPN
dti-1418	256	2	pharm	pharm	PROPN
dti-1418	256	3	des	des	PROPN
dti-1418	256	4	.	.	PROPN
dti-1418	256	5	2015;21:4400–4408	2015;21:4400–4408	NUM
dti-1418	256	6	.	.	PUNCT