id	sid	tid	token	lemma	pos
dti-1424	1	1	drug	drug	NOUN
dti-1424	1	2	target	target	NOUN
dti-1424	1	3	insights	insight	NOUN
dti-1424	1	4	2016:10(s1	2016:10(s1	NUM
dti-1424	1	5	)	)	PUNCT
dti-1424	1	6	15	15	NUM
dti-1424	1	7	this	this	DET
dti-1424	1	8	supplement	supplement	NOUN
dti-1424	1	9	is	be	AUX
dti-1424	1	10	intended	intend	VERB
dti-1424	1	11	to	to	PART
dti-1424	1	12	focus	focus	VERB
dti-1424	1	13	on	on	ADP
dti-1424	1	14	drug	drug	NOUN
dti-1424	1	15	eluting	eluting	NOUN
dti-1424	1	16	devices	device	NOUN
dti-1424	1	17	.	.	PUNCT
dti-1424	2	1	devices	device	NOUN
dti-1424	2	2	(	(	PUNCT
dti-1424	2	3	eg	eg	NOUN
dti-1424	2	4	cardiovascular	cardiovascular	ADJ
dti-1424	2	5	stents	stent	NOUN
dti-1424	2	6	,	,	PUNCT
dti-1424	2	7	drug	drug	NOUN
dti-1424	2	8	delivery	delivery	NOUN
dti-1424	2	9	biopolymers	biopolymer	NOUN
dti-1424	2	10	and	and	CCONJ
dti-1424	2	11	tissue	tissue	NOUN
dti-1424	2	12	engineering	engineering	NOUN
dti-1424	2	13	devices	device	NOUN
dti-1424	2	14	)	)	PUNCT
dti-1424	2	15	,	,	PUNCT
dti-1424	2	16	their	their	PRON
dti-1424	2	17	bio­	bio­	NOUN
dti-1424	2	18	compatibility	compatibility	NOUN
dti-1424	2	19	,	,	PUNCT
dti-1424	2	20	and	and	CCONJ
dti-1424	2	21	mechanisms	mechanism	NOUN
dti-1424	2	22	of	of	ADP
dti-1424	2	23	transport	transport	NOUN
dti-1424	2	24	are	be	AUX
dti-1424	2	25	included	include	VERB
dti-1424	2	26	within	within	ADP
dti-1424	2	27	the	the	DET
dti-1424	2	28	supplement	supplement	NOUN
dti-1424	2	29	’s	’s	PART
dti-1424	2	30	scope	scope	NOUN
dti-1424	2	31	.	.	PUNCT
dti-1424	3	1	drug	drug	NOUN
dti-1424	3	2	target	target	NOUN
dti-1424	3	3	insights	insight	NOUN
dti-1424	3	4	aims	aim	VERB
dti-1424	3	5	to	to	PART
dti-1424	3	6	provide	provide	VERB
dti-1424	3	7	researchers	researcher	NOUN
dti-1424	3	8	working	work	VERB
dti-1424	3	9	in	in	ADP
dti-1424	3	10	this	this	DET
dti-1424	3	11	complex	complex	NOUN
dti-1424	3	12	,	,	PUNCT
dti-1424	3	13	quickly	quickly	ADV
dti-1424	3	14	developing	develop	VERB
dti-1424	3	15	field	field	NOUN
dti-1424	3	16	with	with	ADP
dti-1424	3	17	online	online	ADJ
dti-1424	3	18	,	,	PUNCT
dti-1424	3	19	open	open	ADJ
dti-1424	3	20	access	access	NOUN
dti-1424	3	21	to	to	ADP
dti-1424	3	22	highly	highly	ADV
dti-1424	3	23	relevant	relevant	ADJ
dti-1424	3	24	scholarly	scholarly	ADJ
dti-1424	3	25	articles	article	NOUN
dti-1424	3	26	by	by	ADP
dti-1424	3	27	leading	lead	VERB
dti-1424	3	28	international	international	ADJ
dti-1424	3	29	researchers	researcher	NOUN
dti-1424	3	30	.	.	PUNCT
dti-1424	4	1	in	in	ADP
dti-1424	4	2	a	a	DET
dti-1424	4	3	field	field	NOUN
dti-1424	4	4	where	where	SCONJ
dti-1424	4	5	the	the	DET
dti-1424	4	6	literature	literature	NOUN
dti-1424	4	7	is	be	AUX
dti-1424	4	8	ever	ever	ADV
dti-1424	4	9	-	-	PUNCT
dti-1424	4	10	expanding	expand	VERB
dti-1424	4	11	,	,	PUNCT
dti-1424	4	12	researchers	researcher	NOUN
dti-1424	4	13	increasingly	increasingly	ADV
dti-1424	4	14	need	need	VERB
dti-1424	4	15	access	access	NOUN
dti-1424	4	16	to	to	ADP
dti-1424	4	17	up	up	ADP
dti-1424	4	18	-	-	PUNCT
dti-1424	4	19	to	to	ADP
dti-1424	4	20	-	-	PUNCT
dti-1424	4	21	date	date	NOUN
dti-1424	4	22	,	,	PUNCT
dti-1424	4	23	high	high	ADJ
dti-1424	4	24	quality	quality	NOUN
dti-1424	4	25	scholarly	scholarly	ADJ
dti-1424	4	26	articles	article	NOUN
dti-1424	4	27	on	on	ADP
dti-1424	4	28	areas	area	NOUN
dti-1424	4	29	of	of	ADP
dti-1424	4	30	specific	specific	ADJ
dti-1424	4	31	contemporary	contemporary	ADJ
dti-1424	4	32	interest	interest	NOUN
dti-1424	4	33	.	.	PUNCT
dti-1424	5	1	this	this	DET
dti-1424	5	2	supplement	supplement	NOUN
dti-1424	5	3	aims	aim	VERB
dti-1424	5	4	to	to	PART
dti-1424	5	5	address	address	VERB
dti-1424	5	6	this	this	PRON
dti-1424	5	7	by	by	ADP
dti-1424	5	8	presenting	present	VERB
dti-1424	5	9	high	high	ADJ
dti-1424	5	10	-	-	PUNCT
dti-1424	5	11	quality	quality	NOUN
dti-1424	5	12	articles	article	NOUN
dti-1424	5	13	that	that	PRON
dti-1424	5	14	allow	allow	VERB
dti-1424	5	15	readers	reader	NOUN
dti-1424	5	16	to	to	PART
dti-1424	5	17	distinguish	distinguish	VERB
dti-1424	5	18	the	the	DET
dti-1424	5	19	signal	signal	NOUN
dti-1424	5	20	from	from	ADP
dti-1424	5	21	the	the	DET
dti-1424	5	22	noise	noise	NOUN
dti-1424	5	23	.	.	PUNCT
dti-1424	6	1	the	the	DET
dti-1424	6	2	editor	editor	NOUN
dti-1424	6	3	in	in	ADP
dti-1424	6	4	chief	chief	ADJ
dti-1424	6	5	hopes	hope	NOUN
dti-1424	6	6	that	that	SCONJ
dti-1424	6	7	through	through	ADP
dti-1424	6	8	this	this	DET
dti-1424	6	9	effort	effort	NOUN
dti-1424	6	10	,	,	PUNCT
dti-1424	6	11	practitioners	practitioner	NOUN
dti-1424	6	12	and	and	CCONJ
dti-1424	6	13	researchers	researcher	NOUN
dti-1424	6	14	will	will	AUX
dti-1424	6	15	be	be	AUX
dti-1424	6	16	aided	aid	VERB
dti-1424	6	17	in	in	ADP
dti-1424	6	18	finding	find	VERB
dti-1424	6	19	answers	answer	NOUN
dti-1424	6	20	to	to	ADP
dti-1424	6	21	some	some	PRON
dti-1424	6	22	of	of	ADP
dti-1424	6	23	the	the	DET
dti-1424	6	24	most	most	ADV
dti-1424	6	25	complex	complex	ADJ
dti-1424	6	26	and	and	CCONJ
dti-1424	6	27	pressing	press	VERB
dti-1424	6	28	issues	issue	NOUN
dti-1424	6	29	of	of	ADP
dti-1424	6	30	our	our	PRON
dti-1424	6	31	time	time	NOUN
dti-1424	6	32	.	.	PUNCT
dti-1424	7	1	supplement	supplement	NOUN
dti-1424	7	2	aims	aim	NOUN
dti-1424	7	3	and	and	CCONJ
dti-1424	7	4	scope	scope	NOUN
dti-1424	7	5	journal	journal	PROPN
dti-1424	7	6	name	name	NOUN
dti-1424	7	7	:	:	PUNCT
dti-1424	7	8	drug	drug	NOUN
dti-1424	7	9	target	target	NOUN
dti-1424	7	10	insights	insight	NOUN
dti-1424	7	11	journal	journal	NOUN
dti-1424	7	12	type	type	NOUN
dti-1424	7	13	:	:	PUNCT
dti-1424	7	14	editorial	editorial	ADJ
dti-1424	7	15	year	year	NOUN
dti-1424	7	16	:	:	PUNCT
dti-1424	7	17	2016	2016	NUM
dti-1424	7	18	volume	volume	NOUN
dti-1424	7	19	:	:	PUNCT
dti-1424	7	20	10(s1	10(s1	NUM
dti-1424	7	21	)	)	PUNCT
dti-1424	7	22	running	run	VERB
dti-1424	7	23	head	head	NOUN
dti-1424	7	24	verso	verso	ADJ
dti-1424	7	25	:	:	PUNCT
dti-1424	7	26	spadaccio	spadaccio	NOUN
dti-1424	7	27	et	et	PROPN
dti-1424	7	28	al	al	PROPN
dti-1424	7	29	running	run	VERB
dti-1424	7	30	head	head	NOUN
dti-1424	7	31	recto	recto	NOUN
dti-1424	7	32	:	:	PUNCT
dti-1424	7	33	drug	drug	NOUN
dti-1424	7	34	target	target	NOUN
dti-1424	7	35	insights	insight	NOUN
dti-1424	7	36	introductory	introductory	ADJ
dti-1424	7	37	editorial	editorial	NOUN
dti-1424	7	38	:	:	PUNCT
dti-1424	7	39	drug	drug	NOUN
dti-1424	7	40	-	-	PUNCT
dti-1424	7	41	eluting	elute	VERB
dti-1424	7	42	stents	stent	NOUN
dti-1424	7	43	or	or	CCONJ
dti-1424	7	44	drug	drug	NOUN
dti-1424	7	45	-	-	PUNCT
dti-1424	7	46	eluting	elute	VERB
dti-1424	7	47	grafts	graft	NOUN
dti-1424	7	48	?	?	PUNCT
dti-1424	8	1	insights	insight	NOUN
dti-1424	8	2	from	from	ADP
dti-1424	8	3	proteomic	proteomic	ADJ
dti-1424	8	4	analysis	analysis	NOUN
dti-1424	8	5	§	§	PROPN
dti-1424	8	6	§	§	PROPN
dti-1424	8	7	cristiano	cristiano	PROPN
dti-1424	8	8	spadaccio	spadaccio	PROPN
dti-1424	8	9	current	current	ADJ
dti-1424	8	10	address	address	NOUN
dti-1424	8	11	:	:	PUNCT
dti-1424	8	12	department	department	NOUN
dti-1424	8	13	of	of	ADP
dti-1424	8	14	cardiothoracic	cardiothoracic	NOUN
dti-1424	8	15	surgery	surgery	NOUN
dti-1424	8	16	,	,	PUNCT
dti-1424	8	17	golden	golden	ADJ
dti-1424	8	18	jubilee	jubilee	PROPN
dti-1424	8	19	national	national	PROPN
dti-1424	8	20	hospital	hospital	PROPN
dti-1424	8	21	,	,	PUNCT
dti-1424	8	22	clydebank	clydebank	PROPN
dti-1424	8	23	,	,	PUNCT
dti-1424	8	24	glasgow	glasgow	PROPN
dti-1424	8	25	,	,	PUNCT
dti-1424	8	26	uk	uk	PROPN
dti-1424	8	27	.	.	PROPN
dti-1424	8	28	university	university	PROPN
dti-1424	8	29	of	of	ADP
dti-1424	8	30	glasgow	glasgow	PROPN
dti-1424	8	31	institute	institute	PROPN
dti-1424	8	32	of	of	ADP
dti-1424	8	33	cardiovascular	cardiovascular	ADJ
dti-1424	8	34	and	and	CCONJ
dti-1424	8	35	medical	medical	ADJ
dti-1424	8	36	sciences	science	NOUN
dti-1424	8	37	,	,	PUNCT
dti-1424	8	38	glasgow	glasgow	PROPN
dti-1424	8	39	,	,	PUNCT
dti-1424	8	40	uk	uk	PROPN
dti-1424	8	41	.	.	PROPN
dti-1424	8	42	§	§	PROPN
dti-1424	8	43	§	§	PROPN
dti-1424	8	44	francesco	francesco	PROPN
dti-1424	8	45	nappi	nappi	PROPN
dti-1424	8	46	cardiac	cardiac	PROPN
dti-1424	8	47	surgery	surgery	NOUN
dti-1424	8	48	centre	centre	NOUN
dti-1424	8	49	cardiologique	cardiologique	NOUN
dti-1424	8	50	du	du	PROPN
dti-1424	8	51	nord	nord	PROPN
dti-1424	8	52	de	de	PROPN
dti-1424	8	53	saintdenis	saintdenis	PROPN
dti-1424	8	54	,	,	PUNCT
dti-1424	8	55	paris	paris	PROPN
dti-1424	8	56	,	,	PUNCT
dti-1424	8	57	france	france	PROPN
dti-1424	8	58	.	.	PUNCT
dti-1424	9	1	§	§	PROPN
dti-1424	9	2	§	§	PROPN
dti-1424	9	3	nawwar	nawwar	PROPN
dti-1424	9	4	al	al	PROPN
dti-1424	9	5	-	-	PUNCT
dti-1424	9	6	attar	attar	PROPN
dti-1424	9	7	department	department	PROPN
dti-1424	9	8	of	of	ADP
dti-1424	9	9	cardiothoracic	cardiothoracic	PROPN
dti-1424	9	10	surgery	surgery	NOUN
dti-1424	9	11	,	,	PUNCT
dti-1424	9	12	golden	golden	ADJ
dti-1424	9	13	jubilee	jubilee	PROPN
dti-1424	9	14	national	national	PROPN
dti-1424	9	15	hospital	hospital	PROPN
dti-1424	9	16	,	,	PUNCT
dti-1424	9	17	clydebank	clydebank	PROPN
dti-1424	9	18	,	,	PUNCT
dti-1424	9	19	glasgow	glasgow	PROPN
dti-1424	9	20	,	,	PUNCT
dti-1424	9	21	uk	uk	PROPN
dti-1424	9	22	.	.	PROPN
dti-1424	10	1	§	§	PROPN
dti-1424	10	2	§	§	PROPN
dti-1424	10	3	raffaella	raffaella	PROPN
dti-1424	10	4	coccia	coccia	PROPN
dti-1424	10	5	department	department	PROPN
dti-1424	10	6	of	of	ADP
dti-1424	10	7	biochemical	biochemical	ADJ
dti-1424	10	8	sciences	science	NOUN
dti-1424	10	9	,	,	PUNCT
dti-1424	10	10	sapienza	sapienza	PROPN
dti-1424	10	11	university	university	PROPN
dti-1424	10	12	of	of	ADP
dti-1424	10	13	rome	rome	PROPN
dti-1424	10	14	,	,	PUNCT
dti-1424	10	15	italy	italy	PROPN
dti-1424	10	16	.	.	PUNCT
dti-1424	11	1	§	§	PROPN
dti-1424	11	2	§	§	PROPN
dti-1424	11	3	marzia	marzia	PROPN
dti-1424	11	4	perluigi	perluigi	PROPN
dti-1424	11	5	department	department	PROPN
dti-1424	11	6	of	of	ADP
dti-1424	11	7	biochemical	biochemical	ADJ
dti-1424	11	8	sciences	science	NOUN
dti-1424	11	9	,	,	PUNCT
dti-1424	11	10	sapienza	sapienza	PROPN
dti-1424	11	11	university	university	PROPN
dti-1424	11	12	of	of	ADP
dti-1424	11	13	rome	rome	PROPN
dti-1424	11	14	,	,	PUNCT
dti-1424	11	15	italy	italy	PROPN
dti-1424	11	16	.	.	PUNCT
dti-1424	12	1	§	§	PROPN
dti-1424	12	2	§	§	PROPN
dti-1424	12	3	fabio	fabio	PROPN
dti-1424	12	4	di	di	PROPN
dti-1424	12	5	domenico	domenico	PROPN
dti-1424	12	6	department	department	PROPN
dti-1424	12	7	of	of	ADP
dti-1424	12	8	biochemical	biochemical	ADJ
dti-1424	12	9	sciences	science	NOUN
dti-1424	12	10	,	,	PUNCT
dti-1424	12	11	sapienza	sapienza	PROPN
dti-1424	12	12	university	university	PROPN
dti-1424	12	13	of	of	ADP
dti-1424	12	14	rome	rome	PROPN
dti-1424	12	15	,	,	PUNCT
dti-1424	12	16	italy	italy	PROPN
dti-1424	12	17	.	.	PUNCT
dti-1424	13	1	current	current	ADJ
dti-1424	13	2	developments	development	NOUN
dti-1424	13	3	in	in	ADP
dti-1424	13	4	drug	drug	NOUN
dti-1424	13	5	eluting	eluting	NOUN
dti-1424	13	6	devices	device	NOUN
dti-1424	13	7	the	the	PRON
dti-1424	13	8	rapidly	rapidly	ADV
dti-1424	13	9	expanding	expand	VERB
dti-1424	13	10	panorama	panorama	NOUN
dti-1424	13	11	of	of	ADP
dti-1424	13	12	prosthetic	prosthetic	ADJ
dti-1424	13	13	replacement	replacement	NOUN
dti-1424	13	14	and	and	CCONJ
dti-1424	13	15	interventional	interventional	ADJ
dti-1424	13	16	procedures	procedure	NOUN
dti-1424	13	17	for	for	ADP
dti-1424	13	18	cardiovascular	cardiovascular	ADJ
dti-1424	13	19	disease	disease	NOUN
dti-1424	13	20	demands	demand	VERB
dti-1424	13	21	significant	significant	ADJ
dti-1424	13	22	research	research	NOUN
dti-1424	13	23	for	for	ADP
dti-1424	13	24	the	the	DET
dti-1424	13	25	development	development	NOUN
dti-1424	13	26	of	of	ADP
dti-1424	13	27	devices	device	NOUN
dti-1424	13	28	with	with	ADP
dti-1424	13	29	optimized	optimize	VERB
dti-1424	13	30	characteristics	characteristic	NOUN
dti-1424	13	31	and	and	CCONJ
dti-1424	13	32	performance	performance	NOUN
dti-1424	13	33	to	to	PART
dti-1424	13	34	overcome	overcome	VERB
dti-1424	13	35	the	the	DET
dti-1424	13	36	drawbacks	drawback	NOUN
dti-1424	13	37	of	of	ADP
dti-1424	13	38	the	the	DET
dti-1424	13	39	existing	exist	VERB
dti-1424	13	40	strategies	strategy	NOUN
dti-1424	13	41	.	.	PUNCT
dti-1424	14	1	tissue	tissue	NOUN
dti-1424	14	2	engineering	engineering	NOUN
dti-1424	14	3	is	be	AUX
dti-1424	14	4	a	a	DET
dti-1424	14	5	potent	potent	ADJ
dti-1424	14	6	weapon	weapon	NOUN
dti-1424	14	7	in	in	ADP
dti-1424	14	8	this	this	DET
dti-1424	14	9	scenario	scenario	NOUN
dti-1424	14	10	,	,	PUNCT
dti-1424	14	11	enabling	enable	VERB
dti-1424	14	12	the	the	DET
dti-1424	14	13	realization	realization	NOUN
dti-1424	14	14	of	of	ADP
dti-1424	14	15	sophisticated	sophisticated	ADJ
dti-1424	14	16	biocompatible	biocompatible	ADJ
dti-1424	14	17	devices	device	NOUN
dti-1424	14	18	interacting	interact	VERB
dti-1424	14	19	with	with	ADP
dti-1424	14	20	the	the	DET
dti-1424	14	21	host	host	NOUN
dti-1424	14	22	tissues	tissue	NOUN
dti-1424	14	23	and	and	CCONJ
dti-1424	14	24	influencing	influence	VERB
dti-1424	14	25	their	their	PRON
dti-1424	14	26	behavior	behavior	NOUN
dti-1424	14	27	.	.	PUNCT
dti-1424	15	1	the	the	DET
dti-1424	15	2	fabrication	fabrication	NOUN
dti-1424	15	3	and	and	CCONJ
dti-1424	15	4	design	design	NOUN
dti-1424	15	5	of	of	ADP
dti-1424	15	6	“	"	PUNCT
dti-1424	15	7	smart	smart	ADJ
dti-1424	15	8	”	"	PUNCT
dti-1424	15	9	biomaterials	biomaterial	NOUN
dti-1424	15	10	,	,	PUNCT
dti-1424	15	11	able	able	ADJ
dti-1424	15	12	to	to	PART
dti-1424	15	13	sense	sense	VERB
dti-1424	15	14	and	and	CCONJ
dti-1424	15	15	interact	interact	VERB
dti-1424	15	16	with	with	ADP
dti-1424	15	17	the	the	DET
dti-1424	15	18	biological	biological	ADJ
dti-1424	15	19	milieu	milieu	NOUN
dti-1424	15	20	,	,	PUNCT
dti-1424	15	21	represent	represent	VERB
dti-1424	15	22	a	a	DET
dti-1424	15	23	cornerstone	cornerstone	NOUN
dti-1424	15	24	in	in	ADP
dti-1424	15	25	tissue	tissue	NOUN
dti-1424	15	26	engineering	engineering	NOUN
dti-1424	15	27	and	and	CCONJ
dti-1424	15	28	regenerative	regenerative	ADJ
dti-1424	15	29	medicine	medicine	NOUN
dti-1424	15	30	.	.	PUNCT
dti-1424	16	1	this	this	DET
dti-1424	16	2	development	development	NOUN
dti-1424	16	3	has	have	AUX
dti-1424	16	4	demolished	demolish	VERB
dti-1424	16	5	the	the	DET
dti-1424	16	6	obsolete	obsolete	ADJ
dti-1424	16	7	tenets	tenet	NOUN
dti-1424	16	8	of	of	ADP
dti-1424	16	9	surgery	surgery	NOUN
dti-1424	16	10	implying	implying	ADJ
dti-1424	16	11	reconstructing	reconstruct	VERB
dti-1424	16	12	organs	organ	NOUN
dti-1424	16	13	or	or	CCONJ
dti-1424	16	14	part	part	NOUN
dti-1424	16	15	of	of	ADP
dti-1424	16	16	them	they	PRON
dti-1424	16	17	with	with	ADP
dti-1424	16	18	artificial	artificial	ADJ
dti-1424	16	19	materials	material	NOUN
dti-1424	16	20	.	.	PUNCT
dti-1424	17	1	the	the	DET
dti-1424	17	2	deeper	deep	ADJ
dti-1424	17	3	understanding	understanding	NOUN
dti-1424	17	4	achieved	achieve	VERB
dti-1424	17	5	by	by	ADP
dti-1424	17	6	modern	modern	ADJ
dti-1424	17	7	research	research	NOUN
dti-1424	17	8	has	have	AUX
dti-1424	17	9	highlighted	highlight	VERB
dti-1424	17	10	the	the	DET
dti-1424	17	11	limitations	limitation	NOUN
dti-1424	17	12	and	and	CCONJ
dti-1424	17	13	the	the	DET
dti-1424	17	14	biological	biological	ADJ
dti-1424	17	15	and	and	CCONJ
dti-1424	17	16	clinical	clinical	ADJ
dti-1424	17	17	drawbacks	drawback	NOUN
dti-1424	17	18	of	of	ADP
dti-1424	17	19	the	the	DET
dti-1424	17	20	long	long	ADJ
dti-1424	17	21	-	-	PUNCT
dti-1424	17	22	term	term	NOUN
dti-1424	17	23	coexistence	coexistence	NOUN
dti-1424	17	24	of	of	ADP
dti-1424	17	25	a	a	DET
dti-1424	17	26	foreign	foreign	ADJ
dti-1424	17	27	material	material	NOUN
dti-1424	17	28	in	in	ADP
dti-1424	17	29	the	the	DET
dti-1424	17	30	body	body	NOUN
dti-1424	17	31	,	,	PUNCT
dti-1424	17	32	especially	especially	ADV
dti-1424	17	33	in	in	ADP
dti-1424	17	34	the	the	DET
dti-1424	17	35	cardiovascular	cardiovascular	ADJ
dti-1424	17	36	system.1	system.1	VERB
dti-1424	17	37	the	the	DET
dti-1424	17	38	need	need	NOUN
dti-1424	17	39	to	to	PART
dti-1424	17	40	respect	respect	VERB
dti-1424	17	41	the	the	DET
dti-1424	17	42	physiological	physiological	ADJ
dti-1424	17	43	reparative	reparative	NOUN
dti-1424	17	44	and	and	CCONJ
dti-1424	17	45	remodeling	remodeling	NOUN
dti-1424	17	46	processes	process	NOUN
dti-1424	17	47	normally	normally	ADV
dti-1424	17	48	occurring	occur	VERB
dti-1424	17	49	in	in	ADP
dti-1424	17	50	nature	nature	NOUN
dti-1424	17	51	progressively	progressively	ADV
dti-1424	17	52	achieved	achieve	VERB
dti-1424	17	53	significance	significance	NOUN
dti-1424	17	54	in	in	ADP
dti-1424	17	55	the	the	DET
dti-1424	17	56	current	current	ADJ
dti-1424	17	57	research,2,3	research,2,3	NOUN
dti-1424	17	58	demonstrating	demonstrate	VERB
dti-1424	17	59	the	the	DET
dti-1424	17	60	necessity	necessity	NOUN
dti-1424	17	61	to	to	PART
dti-1424	17	62	accompany	accompany	VERB
dti-1424	17	63	the	the	DET
dti-1424	17	64	body	body	NOUN
dti-1424	17	65	’s	’s	PART
dti-1424	17	66	physiological	physiological	ADJ
dti-1424	17	67	responses	response	NOUN
dti-1424	17	68	and	and	CCONJ
dti-1424	17	69	the	the	DET
dti-1424	17	70	activities	activity	NOUN
dti-1424	17	71	of	of	ADP
dti-1424	17	72	tissue	tissue	NOUN
dti-1424	17	73	regeneration	regeneration	NOUN
dti-1424	17	74	rather	rather	ADV
dti-1424	17	75	than	than	ADP
dti-1424	17	76	pretending	pretend	VERB
dti-1424	17	77	to	to	PART
dti-1424	17	78	replace	replace	VERB
dti-1424	17	79	them	they	PRON
dti-1424	17	80	with	with	ADP
dti-1424	17	81	“	"	PUNCT
dti-1424	17	82	plastic	plastic	ADJ
dti-1424	17	83	”	"	PUNCT
dti-1424	17	84	surrogates	surrogate	NOUN
dti-1424	17	85	.	.	PUNCT
dti-1424	18	1	this	this	DET
dti-1424	18	2	attention	attention	NOUN
dti-1424	18	3	to	to	ADP
dti-1424	18	4	the	the	DET
dti-1424	18	5	biology	biology	NOUN
dti-1424	18	6	of	of	ADP
dti-1424	18	7	regeneration	regeneration	NOUN
dti-1424	18	8	in	in	ADP
dti-1424	18	9	tissue	tissue	NOUN
dti-1424	18	10	engineering	engineering	NOUN
dti-1424	18	11	and	and	CCONJ
dti-1424	18	12	to	to	ADP
dti-1424	18	13	micro	micro	ADJ
dti-1424	18	14	-	-	ADJ
dti-1424	18	15	environmental	environmental	ADJ
dti-1424	18	16	conditions	condition	NOUN
dti-1424	18	17	at	at	ADP
dti-1424	18	18	the	the	DET
dti-1424	18	19	tissue	tissue	NOUN
dti-1424	18	20	and	and	CCONJ
dti-1424	18	21	cellular	cellular	ADJ
dti-1424	18	22	levels	level	NOUN
dti-1424	18	23	is	be	AUX
dti-1424	18	24	expressed	express	VERB
dti-1424	18	25	in	in	ADP
dti-1424	18	26	the	the	DET
dti-1424	18	27	articles	article	NOUN
dti-1424	18	28	of	of	ADP
dti-1424	18	29	this	this	DET
dti-1424	18	30	special	special	ADJ
dti-1424	18	31	issue	issue	NOUN
dti-1424	18	32	of	of	ADP
dti-1424	18	33	drug	drug	NOUN
dti-1424	18	34	target	target	NOUN
dti-1424	18	35	insights	insight	NOUN
dti-1424	18	36	.	.	PUNCT
dti-1424	19	1	interesting	interesting	ADJ
dti-1424	19	2	and	and	CCONJ
dti-1424	19	3	sophisticated	sophisticated	ADJ
dti-1424	19	4	approaches	approach	NOUN
dti-1424	19	5	are	be	AUX
dti-1424	19	6	proposed	propose	VERB
dti-1424	19	7	in	in	ADP
dti-1424	19	8	this	this	DET
dti-1424	19	9	context	context	NOUN
dti-1424	19	10	,	,	PUNCT
dti-1424	19	11	entailing	entail	VERB
dti-1424	19	12	the	the	DET
dti-1424	19	13	use	use	NOUN
dti-1424	19	14	of	of	ADP
dti-1424	19	15	drug	drug	NOUN
dti-1424	19	16	-	-	PUNCT
dti-1424	19	17	delivery	delivery	NOUN
dti-1424	19	18	http://www.la-press.com/drug-target-insights-journal-j23	http://www.la-press.com/drug-target-insights-journal-j23	PROPN
dti-1424	19	19	http://www.la-press.com	http://www.la-press.com	X
dti-1424	19	20	spadaccio	spadaccio	PROPN
dti-1424	19	21	et	et	PROPN
dti-1424	19	22	al	al	PROPN
dti-1424	19	23	drug	drug	PROPN
dti-1424	19	24	target	target	NOUN
dti-1424	19	25	insights	insight	NOUN
dti-1424	19	26	2016:10(s1)16	2016:10(s1)16	NUM
dti-1424	19	27	devices	device	NOUN
dti-1424	19	28	that	that	PRON
dti-1424	19	29	release	release	VERB
dti-1424	19	30	tailored	tailor	VERB
dti-1424	19	31	compounds	compound	NOUN
dti-1424	19	32	to	to	PART
dti-1424	19	33	target	target	VERB
dti-1424	19	34	specific	specific	ADJ
dti-1424	19	35	aspects	aspect	NOUN
dti-1424	19	36	of	of	ADP
dti-1424	19	37	diseases	disease	NOUN
dti-1424	19	38	or	or	CCONJ
dti-1424	19	39	complications	complication	NOUN
dti-1424	19	40	.	.	PUNCT
dti-1424	20	1	in	in	ADP
dti-1424	20	2	this	this	DET
dti-1424	20	3	issue	issue	NOUN
dti-1424	20	4	,	,	PUNCT
dti-1424	20	5	dr	dr	PROPN
dti-1424	20	6	rapetto	rapetto	PROPN
dti-1424	20	7	and	and	CCONJ
dti-1424	20	8	colleagues	colleague	NOUN
dti-1424	20	9	extensively	extensively	ADV
dti-1424	20	10	reviewed	review	VERB
dti-1424	20	11	the	the	DET
dti-1424	20	12	role	role	NOUN
dti-1424	20	13	of	of	ADP
dti-1424	20	14	gentamicinimpregnated	gentamicinimpregnate	VERB
dti-1424	20	15	collagen	collagen	NOUN
dti-1424	20	16	sponges	sponge	NOUN
dti-1424	20	17	(	(	PUNCT
dti-1424	20	18	gicss	gicss	PROPN
dti-1424	20	19	)	)	PUNCT
dti-1424	20	20	in	in	ADP
dti-1424	20	21	preventing	prevent	VERB
dti-1424	20	22	sternal	sternal	ADJ
dti-1424	20	23	wound	wound	NOUN
dti-1424	20	24	infection	infection	NOUN
dti-1424	20	25	.	.	PUNCT
dti-1424	21	1	the	the	DET
dti-1424	21	2	use	use	NOUN
dti-1424	21	3	of	of	ADP
dti-1424	21	4	these	these	DET
dti-1424	21	5	delivery	delivery	NOUN
dti-1424	21	6	devices	device	NOUN
dti-1424	21	7	allows	allow	VERB
dti-1424	21	8	for	for	ADP
dti-1424	21	9	topical	topical	ADJ
dti-1424	21	10	delivery	delivery	NOUN
dti-1424	21	11	of	of	ADP
dti-1424	21	12	high	high	ADJ
dti-1424	21	13	antibiotic	antibiotic	ADJ
dti-1424	21	14	concentrations	concentration	NOUN
dti-1424	21	15	to	to	ADP
dti-1424	21	16	the	the	DET
dti-1424	21	17	wound	wound	NOUN
dti-1424	21	18	,	,	PUNCT
dti-1424	21	19	reducing	reduce	VERB
dti-1424	21	20	the	the	DET
dti-1424	21	21	complications	complication	NOUN
dti-1424	21	22	associated	associate	VERB
dti-1424	21	23	with	with	ADP
dti-1424	21	24	gentamycin	gentamycin	PROPN
dti-1424	21	25	toxicity.4	toxicity.4	VERB
dti-1424	21	26	on	on	ADP
dti-1424	21	27	the	the	DET
dti-1424	21	28	other	other	ADJ
dti-1424	21	29	side	side	NOUN
dti-1424	21	30	,	,	PUNCT
dti-1424	21	31	alternative	alternative	ADJ
dti-1424	21	32	use	use	NOUN
dti-1424	21	33	of	of	ADP
dti-1424	21	34	smart	smart	ADJ
dti-1424	21	35	biopolymers	biopolymer	NOUN
dti-1424	21	36	able	able	ADJ
dti-1424	21	37	to	to	PART
dti-1424	21	38	release	release	VERB
dti-1424	21	39	anticoagulant	anticoagulant	ADJ
dti-1424	21	40	agents	agent	NOUN
dti-1424	21	41	,	,	PUNCT
dti-1424	21	42	such	such	ADJ
dti-1424	21	43	as	as	ADP
dti-1424	21	44	heparin	heparin	NOUN
dti-1424	21	45	,	,	PUNCT
dti-1424	21	46	to	to	PART
dti-1424	21	47	avoid	avoid	VERB
dti-1424	21	48	early	early	ADJ
dti-1424	21	49	vascular	vascular	ADJ
dti-1424	21	50	graft	graft	NOUN
dti-1424	21	51	thrombosis	thrombosis	NOUN
dti-1424	21	52	and	and	CCONJ
dti-1424	21	53	failure	failure	NOUN
dti-1424	21	54	will	will	AUX
dti-1424	21	55	be	be	AUX
dti-1424	21	56	presented	present	VERB
dti-1424	21	57	and	and	CCONJ
dti-1424	21	58	discussed	discuss	VERB
dti-1424	21	59	in	in	ADP
dti-1424	21	60	the	the	DET
dti-1424	21	61	same	same	ADJ
dti-1424	21	62	issue	issue	NOUN
dti-1424	21	63	of	of	ADP
dti-1424	21	64	the	the	DET
dti-1424	21	65	journal.5	journal.5	PROPN
dti-1424	21	66	these	these	PRON
dti-1424	21	67	are	be	AUX
dti-1424	21	68	not	not	PART
dti-1424	21	69	the	the	DET
dti-1424	21	70	only	only	ADJ
dti-1424	21	71	applications	application	NOUN
dti-1424	21	72	in	in	ADP
dti-1424	21	73	this	this	DET
dti-1424	21	74	field	field	NOUN
dti-1424	21	75	,	,	PUNCT
dti-1424	21	76	as	as	SCONJ
dti-1424	21	77	demonstrated	demonstrate	VERB
dti-1424	21	78	by	by	ADP
dti-1424	21	79	other	other	ADJ
dti-1424	21	80	papers	paper	NOUN
dti-1424	21	81	in	in	ADP
dti-1424	21	82	this	this	DET
dti-1424	21	83	issue	issue	NOUN
dti-1424	21	84	.	.	PUNCT
dti-1424	22	1	indeed	indeed	ADV
dti-1424	22	2	,	,	PUNCT
dti-1424	22	3	at	at	ADP
dti-1424	22	4	the	the	DET
dti-1424	22	5	experimental	experimental	ADJ
dti-1424	22	6	level	level	NOUN
dti-1424	22	7	,	,	PUNCT
dti-1424	22	8	several	several	ADJ
dti-1424	22	9	research	research	NOUN
dti-1424	22	10	efforts	effort	NOUN
dti-1424	22	11	have	have	AUX
dti-1424	22	12	been	be	AUX
dti-1424	22	13	engaged	engage	VERB
dti-1424	22	14	in	in	ADP
dti-1424	22	15	designing	design	VERB
dti-1424	22	16	scaffold	scaffold	NOUN
dti-1424	22	17	-	-	PUNCT
dti-1424	22	18	releasing	releasing	NOUN
dti-1424	22	19	factors	factor	NOUN
dti-1424	22	20	,	,	PUNCT
dti-1424	22	21	drugs	drug	NOUN
dti-1424	22	22	or	or	CCONJ
dti-1424	22	23	cytokines	cytokine	NOUN
dti-1424	22	24	to	to	PART
dti-1424	22	25	improve	improve	VERB
dti-1424	22	26	tissue	tissue	NOUN
dti-1424	22	27	regeneration	regeneration	NOUN
dti-1424	22	28	or	or	CCONJ
dti-1424	22	29	stem	stem	NOUN
dti-1424	22	30	cell	cell	NOUN
dti-1424	22	31	recruitment	recruitment	NOUN
dti-1424	22	32	,	,	PUNCT
dti-1424	22	33	or	or	CCONJ
dti-1424	22	34	to	to	PART
dti-1424	22	35	overcome	overcome	VERB
dti-1424	22	36	prosthesis	prosthesis	NOUN
dti-1424	22	37	-	-	PUNCT
dti-1424	22	38	related	relate	VERB
dti-1424	22	39	issues.6	issues.6	PROPN
dti-1424	22	40	the	the	DET
dti-1424	22	41	possibility	possibility	NOUN
dti-1424	22	42	to	to	PART
dti-1424	22	43	tailor	tailor	VERB
dti-1424	22	44	a	a	DET
dti-1424	22	45	bioresorbable	bioresorbable	ADJ
dti-1424	22	46	scaffold	scaffold	NOUN
dti-1424	22	47	in	in	ADP
dti-1424	22	48	order	order	NOUN
dti-1424	22	49	to	to	PART
dti-1424	22	50	create	create	VERB
dti-1424	22	51	a	a	DET
dti-1424	22	52	microenvironment	microenvironment	NOUN
dti-1424	22	53	able	able	ADJ
dti-1424	22	54	to	to	PART
dti-1424	22	55	boost	boost	VERB
dti-1424	22	56	or	or	CCONJ
dti-1424	22	57	guide	guide	VERB
dti-1424	22	58	tissue	tissue	NOUN
dti-1424	22	59	regeneration	regeneration	NOUN
dti-1424	22	60	is	be	AUX
dti-1424	22	61	an	an	DET
dti-1424	22	62	exciting	exciting	ADJ
dti-1424	22	63	area	area	NOUN
dti-1424	22	64	of	of	ADP
dti-1424	22	65	investigation.7,8	investigation.7,8	NOUN
dti-1424	22	66	additionally	additionally	ADV
dti-1424	22	67	,	,	PUNCT
dti-1424	22	68	drug	drug	NOUN
dti-1424	22	69	-	-	PUNCT
dti-1424	22	70	releasing	release	VERB
dti-1424	22	71	devices	device	NOUN
dti-1424	22	72	might	might	AUX
dti-1424	22	73	also	also	ADV
dti-1424	22	74	allow	allow	VERB
dti-1424	22	75	avoidance	avoidance	NOUN
dti-1424	22	76	or	or	CCONJ
dti-1424	22	77	treatment	treatment	NOUN
dti-1424	22	78	of	of	ADP
dti-1424	22	79	some	some	PRON
dti-1424	22	80	of	of	ADP
dti-1424	22	81	the	the	DET
dti-1424	22	82	drawbacks	drawback	NOUN
dti-1424	22	83	related	relate	VERB
dti-1424	22	84	to	to	ADP
dti-1424	22	85	prosthetic	prosthetic	ADJ
dti-1424	22	86	replacement	replacement	NOUN
dti-1424	22	87	of	of	ADP
dti-1424	22	88	cardiovascular	cardiovascular	ADJ
dti-1424	22	89	structures.5,6	structures.5,6	NOUN
dti-1424	22	90	in	in	ADP
dti-1424	22	91	the	the	DET
dti-1424	22	92	field	field	NOUN
dti-1424	22	93	of	of	ADP
dti-1424	22	94	interventional	interventional	ADJ
dti-1424	22	95	cardiology	cardiology	NOUN
dti-1424	22	96	there	there	PRON
dti-1424	22	97	is	be	VERB
dti-1424	22	98	a	a	DET
dti-1424	22	99	widespread	widespread	ADJ
dti-1424	22	100	use	use	NOUN
dti-1424	22	101	of	of	ADP
dti-1424	22	102	drug	drug	NOUN
dti-1424	22	103	-	-	PUNCT
dti-1424	22	104	releasing	release	VERB
dti-1424	22	105	stents	stent	NOUN
dti-1424	22	106	,	,	PUNCT
dti-1424	22	107	in	in	ADP
dti-1424	22	108	particular	particular	ADJ
dti-1424	22	109	of	of	ADP
dti-1424	22	110	steroids	steroid	NOUN
dti-1424	22	111	or	or	CCONJ
dti-1424	22	112	antiproliferative	antiproliferative	ADJ
dti-1424	22	113	agents	agent	NOUN
dti-1424	22	114	in	in	ADP
dti-1424	22	115	order	order	NOUN
dti-1424	22	116	to	to	PART
dti-1424	22	117	prevent	prevent	VERB
dti-1424	22	118	neointimal	neointimal	ADJ
dti-1424	22	119	hyperplasia	hyperplasia	NOUN
dti-1424	22	120	.	.	PUNCT
dti-1424	23	1	interestingly	interestingly	ADV
dti-1424	23	2	,	,	PUNCT
dti-1424	23	3	the	the	DET
dti-1424	23	4	concept	concept	NOUN
dti-1424	23	5	of	of	ADP
dti-1424	23	6	paracrine	paracrine	NOUN
dti-1424	23	7	or	or	CCONJ
dti-1424	23	8	local	local	ADJ
dti-1424	23	9	release	release	NOUN
dti-1424	23	10	of	of	ADP
dti-1424	23	11	molecules	molecule	NOUN
dti-1424	23	12	with	with	ADP
dti-1424	23	13	modulatory	modulatory	ADJ
dti-1424	23	14	or	or	CCONJ
dti-1424	23	15	homeostatic	homeostatic	ADJ
dti-1424	23	16	action	action	NOUN
dti-1424	23	17	is	be	AUX
dti-1424	23	18	not	not	PART
dti-1424	23	19	new	new	ADJ
dti-1424	23	20	in	in	ADP
dti-1424	23	21	biology	biology	NOUN
dti-1424	23	22	.	.	PUNCT
dti-1424	24	1	endothelium	endothelium	NOUN
dti-1424	24	2	-	-	PUNCT
dti-1424	24	3	mediated	mediate	VERB
dti-1424	24	4	release	release	NOUN
dti-1424	24	5	of	of	ADP
dti-1424	24	6	growth	growth	NOUN
dti-1424	24	7	factors	factor	NOUN
dti-1424	24	8	and	and	CCONJ
dti-1424	24	9	regulatory	regulatory	ADJ
dti-1424	24	10	molecules	molecule	NOUN
dti-1424	24	11	is	be	AUX
dti-1424	24	12	a	a	DET
dti-1424	24	13	well	well	ADV
dti-1424	24	14	-	-	PUNCT
dti-1424	24	15	accepted	accept	VERB
dti-1424	24	16	natural	natural	ADJ
dti-1424	24	17	mechanism	mechanism	NOUN
dti-1424	24	18	to	to	PART
dti-1424	24	19	locally	locally	ADV
dti-1424	24	20	and	and	CCONJ
dti-1424	24	21	remotely	remotely	ADV
dti-1424	24	22	control	control	VERB
dti-1424	24	23	or	or	CCONJ
dti-1424	24	24	respond	respond	VERB
dti-1424	24	25	to	to	ADP
dti-1424	24	26	a	a	DET
dti-1424	24	27	variety	variety	NOUN
dti-1424	24	28	of	of	ADP
dti-1424	24	29	physiological	physiological	ADJ
dti-1424	24	30	or	or	CCONJ
dti-1424	24	31	pathological	pathological	ADJ
dti-1424	24	32	conditions	condition	NOUN
dti-1424	24	33	,	,	PUNCT
dti-1424	24	34	and	and	CCONJ
dti-1424	24	35	different	different	ADJ
dti-1424	24	36	parts	part	NOUN
dti-1424	24	37	of	of	ADP
dti-1424	24	38	the	the	DET
dti-1424	24	39	vascular	vascular	ADJ
dti-1424	24	40	tree	tree	NOUN
dti-1424	24	41	might	might	AUX
dti-1424	24	42	behave	behave	VERB
dti-1424	24	43	differently	differently	ADV
dti-1424	24	44	according	accord	VERB
dti-1424	24	45	to	to	ADP
dti-1424	24	46	their	their	PRON
dti-1424	24	47	biological	biological	ADJ
dti-1424	24	48	needs	need	NOUN
dti-1424	24	49	.	.	PUNCT
dti-1424	25	1	this	this	DET
dti-1424	25	2	concept	concept	NOUN
dti-1424	25	3	has	have	VERB
dti-1424	25	4	important	important	ADJ
dti-1424	25	5	ramifications	ramification	NOUN
dti-1424	25	6	also	also	ADV
dti-1424	25	7	in	in	ADP
dti-1424	25	8	the	the	DET
dti-1424	25	9	clinical	clinical	ADJ
dti-1424	25	10	side	side	NOUN
dti-1424	25	11	,	,	PUNCT
dti-1424	25	12	especially	especially	ADV
dti-1424	25	13	when	when	SCONJ
dti-1424	25	14	treating	treat	VERB
dti-1424	25	15	cardiovascular	cardiovascular	ADJ
dti-1424	25	16	structures	structure	NOUN
dti-1424	25	17	.	.	PUNCT
dti-1424	26	1	release	release	NOUN
dti-1424	26	2	of	of	ADP
dti-1424	26	3	drug	drug	NOUN
dti-1424	26	4	from	from	ADP
dti-1424	26	5	coronary	coronary	ADJ
dti-1424	26	6	stents	stent	NOUN
dti-1424	26	7	(	(	PUNCT
dti-1424	26	8	drug	drug	NOUN
dti-1424	26	9	-	-	PUNCT
dti-1424	26	10	eluting	elute	VERB
dti-1424	26	11	stents	stent	NOUN
dti-1424	26	12	,	,	PUNCT
dti-1424	26	13	des	des	PROPN
dti-1424	26	14	)	)	PUNCT
dti-1424	26	15	able	able	ADJ
dti-1424	26	16	to	to	PART
dti-1424	26	17	influence	influence	VERB
dti-1424	26	18	or	or	CCONJ
dti-1424	26	19	modify	modify	VERB
dti-1424	26	20	endothelial	endothelial	ADJ
dti-1424	26	21	homeostasis	homeostasis	NOUN
dti-1424	26	22	and	and	CCONJ
dti-1424	26	23	function	function	NOUN
dti-1424	26	24	is	be	AUX
dti-1424	26	25	an	an	DET
dti-1424	26	26	example	example	NOUN
dti-1424	26	27	.	.	PUNCT
dti-1424	27	1	more	more	ADV
dti-1424	27	2	interestingly	interestingly	ADV
dti-1424	27	3	,	,	PUNCT
dti-1424	27	4	the	the	DET
dti-1424	27	5	use	use	NOUN
dti-1424	27	6	of	of	ADP
dti-1424	27	7	autologous	autologous	ADJ
dti-1424	27	8	non	non	ADJ
dti-1424	27	9	-	-	ADJ
dti-1424	27	10	artificial	artificial	ADJ
dti-1424	27	11	conduits	conduit	NOUN
dti-1424	27	12	in	in	ADP
dti-1424	27	13	coronary	coronary	ADJ
dti-1424	27	14	artery	artery	NOUN
dti-1424	27	15	bypass	bypass	NOUN
dti-1424	27	16	graft	graft	NOUN
dti-1424	27	17	(	(	PUNCT
dti-1424	27	18	cabg	cabg	ADJ
dti-1424	27	19	)	)	PUNCT
dti-1424	27	20	surgery	surgery	NOUN
dti-1424	27	21	might	might	AUX
dti-1424	27	22	be	be	AUX
dti-1424	27	23	considered	consider	VERB
dti-1424	27	24	another	another	DET
dti-1424	27	25	intriguing	intriguing	ADJ
dti-1424	27	26	system	system	NOUN
dti-1424	27	27	of	of	ADP
dti-1424	27	28	“	"	PUNCT
dti-1424	27	29	natural	natural	ADJ
dti-1424	27	30	”	"	PUNCT
dti-1424	27	31	drug	drug	NOUN
dti-1424	27	32	delivery	delivery	NOUN
dti-1424	27	33	device	device	NOUN
dti-1424	27	34	.	.	PUNCT
dti-1424	28	1	cabg	cabg	PROPN
dti-1424	28	2	might	might	AUX
dti-1424	28	3	be	be	AUX
dti-1424	28	4	performed	perform	VERB
dti-1424	28	5	using	use	VERB
dti-1424	28	6	autologous	autologous	ADJ
dti-1424	28	7	saphenous	saphenous	ADJ
dti-1424	28	8	vein	vein	NOUN
dti-1424	28	9	or	or	CCONJ
dti-1424	28	10	internal	internal	ADJ
dti-1424	28	11	thoracic	thoracic	NOUN
dti-1424	28	12	artery	artery	NOUN
dti-1424	28	13	(	(	PUNCT
dti-1424	28	14	ita	ita	NOUN
dti-1424	28	15	or	or	CCONJ
dti-1424	28	16	mammary	mammary	ADJ
dti-1424	28	17	artery	artery	NOUN
dti-1424	28	18	)	)	PUNCT
dti-1424	28	19	,	,	PUNCT
dti-1424	28	20	two	two	NUM
dti-1424	28	21	conduits	conduit	NOUN
dti-1424	28	22	with	with	ADP
dti-1424	28	23	profoundly	profoundly	ADV
dti-1424	28	24	different	different	ADJ
dti-1424	28	25	biological	biological	ADJ
dti-1424	28	26	features	feature	NOUN
dti-1424	28	27	and	and	CCONJ
dti-1424	28	28	structure	structure	NOUN
dti-1424	28	29	.	.	PUNCT
dti-1424	29	1	there	there	PRON
dti-1424	29	2	is	be	VERB
dti-1424	29	3	a	a	DET
dti-1424	29	4	general	general	ADJ
dti-1424	29	5	consensus	consensus	NOUN
dti-1424	29	6	on	on	ADP
dti-1424	29	7	the	the	DET
dti-1424	29	8	accelerated	accelerated	ADJ
dti-1424	29	9	degeneration	degeneration	NOUN
dti-1424	29	10	of	of	ADP
dti-1424	29	11	venous	venous	ADJ
dti-1424	29	12	grafts	graft	NOUN
dti-1424	29	13	after	after	ADP
dti-1424	29	14	surgery	surgery	NOUN
dti-1424	29	15	,	,	PUNCT
dti-1424	29	16	with	with	ADP
dti-1424	29	17	extremely	extremely	ADV
dti-1424	29	18	high	high	ADJ
dti-1424	29	19	incidence	incidence	NOUN
dti-1424	29	20	of	of	ADP
dti-1424	29	21	failure	failure	NOUN
dti-1424	29	22	and	and	CCONJ
dti-1424	29	23	lower	low	ADJ
dti-1424	29	24	patency	patency	NOUN
dti-1424	29	25	rates	rate	NOUN
dti-1424	29	26	in	in	ADP
dti-1424	29	27	comparison	comparison	NOUN
dti-1424	29	28	to	to	ADP
dti-1424	29	29	arterial	arterial	ADJ
dti-1424	29	30	grafts	graft	NOUN
dti-1424	29	31	.	.	PUNCT
dti-1424	30	1	this	this	DET
dti-1424	30	2	difference	difference	NOUN
dti-1424	30	3	in	in	ADP
dti-1424	30	4	angiographic	angiographic	ADJ
dti-1424	30	5	patency	patency	NOUN
dti-1424	30	6	was	be	AUX
dti-1424	30	7	shown	show	VERB
dti-1424	30	8	to	to	PART
dti-1424	30	9	be	be	AUX
dti-1424	30	10	associated	associate	VERB
dti-1424	30	11	with	with	ADP
dti-1424	30	12	improved	improve	VERB
dti-1424	30	13	clinical	clinical	ADJ
dti-1424	30	14	outcomes	outcome	NOUN
dti-1424	30	15	and	and	CCONJ
dti-1424	30	16	rates	rate	NOUN
dti-1424	30	17	of	of	ADP
dti-1424	30	18	ischemia	ischemia	NOUN
dti-1424	30	19	-	-	PUNCT
dti-1424	30	20	free	free	ADJ
dti-1424	30	21	survival	survival	NOUN
dti-1424	30	22	in	in	ADP
dti-1424	30	23	patients	patient	NOUN
dti-1424	30	24	undergoing	undergo	VERB
dti-1424	30	25	exclusive	exclusive	ADJ
dti-1424	30	26	arterial	arterial	ADJ
dti-1424	30	27	revascularization	revascularization	NOUN
dti-1424	30	28	,	,	PUNCT
dti-1424	30	29	especially	especially	ADV
dti-1424	30	30	in	in	ADP
dti-1424	30	31	case	case	NOUN
dti-1424	30	32	of	of	ADP
dti-1424	30	33	subjects	subject	NOUN
dti-1424	30	34	who	who	PRON
dti-1424	30	35	previously	previously	ADV
dti-1424	30	36	developed	develop	VERB
dti-1424	30	37	in	in	ADP
dti-1424	30	38	-	-	PUNCT
dti-1424	30	39	stent	stent	VERB
dti-1424	30	40	restenosis.9	restenosis.9	NOUN
dti-1424	30	41	construction	construction	NOUN
dti-1424	30	42	of	of	ADP
dti-1424	30	43	coronary	coronary	ADJ
dti-1424	30	44	graft	graft	NOUN
dti-1424	30	45	through	through	ADP
dti-1424	30	46	the	the	DET
dti-1424	30	47	use	use	NOUN
dti-1424	30	48	of	of	ADP
dti-1424	30	49	arterial	arterial	ADJ
dti-1424	30	50	conduits	conduit	NOUN
dti-1424	30	51	,	,	PUNCT
dti-1424	30	52	especially	especially	ADV
dti-1424	30	53	with	with	ADP
dti-1424	30	54	internal	internal	ADJ
dti-1424	30	55	thoracic	thoracic	NOUN
dti-1424	30	56	artery	artery	NOUN
dti-1424	30	57	(	(	PUNCT
dti-1424	30	58	ita	ita	NOUN
dti-1424	30	59	)	)	PUNCT
dti-1424	30	60	,	,	PUNCT
dti-1424	30	61	is	be	AUX
dti-1424	30	62	therefore	therefore	ADV
dti-1424	30	63	advocated	advocate	VERB
dti-1424	30	64	as	as	ADP
dti-1424	30	65	desirable	desirable	ADJ
dti-1424	30	66	to	to	PART
dti-1424	30	67	ensure	ensure	VERB
dti-1424	30	68	long	long	ADJ
dti-1424	30	69	-	-	PUNCT
dti-1424	30	70	term	term	NOUN
dti-1424	30	71	patency	patency	NOUN
dti-1424	30	72	and	and	CCONJ
dti-1424	30	73	optimal	optimal	ADJ
dti-1424	30	74	clinical	clinical	ADJ
dti-1424	30	75	outcomes.10,11	outcomes.10,11	NOUN
dti-1424	30	76	the	the	DET
dti-1424	30	77	biological	biological	ADJ
dti-1424	30	78	mechanisms	mechanism	NOUN
dti-1424	30	79	underlying	underlie	VERB
dti-1424	30	80	the	the	DET
dti-1424	30	81	poorer	poor	ADJ
dti-1424	30	82	outcomes	outcome	NOUN
dti-1424	30	83	of	of	ADP
dti-1424	30	84	venous	venous	ADJ
dti-1424	30	85	grafts	graft	NOUN
dti-1424	30	86	in	in	ADP
dti-1424	30	87	respect	respect	NOUN
dti-1424	30	88	to	to	ADP
dti-1424	30	89	arterial	arterial	ADJ
dti-1424	30	90	ones	one	NOUN
dti-1424	30	91	are	be	AUX
dti-1424	30	92	not	not	PART
dti-1424	30	93	well	well	ADV
dti-1424	30	94	understood	understand	VERB
dti-1424	30	95	and	and	CCONJ
dti-1424	30	96	still	still	ADV
dti-1424	30	97	a	a	DET
dti-1424	30	98	matter	matter	NOUN
dti-1424	30	99	of	of	ADP
dti-1424	30	100	debate	debate	NOUN
dti-1424	30	101	.	.	PUNCT
dti-1424	31	1	reduced	reduce	VERB
dti-1424	31	2	production	production	NOUN
dti-1424	31	3	of	of	ADP
dti-1424	31	4	nitric	nitric	ADJ
dti-1424	31	5	oxide	oxide	NOUN
dti-1424	31	6	has	have	AUX
dti-1424	31	7	been	be	AUX
dti-1424	31	8	claimed	claim	VERB
dti-1424	31	9	as	as	ADP
dti-1424	31	10	a	a	DET
dti-1424	31	11	primary	primary	ADJ
dti-1424	31	12	factor,12	factor,12	NOUN
dti-1424	31	13	implicated	implicate	VERB
dti-1424	31	14	in	in	ADP
dti-1424	31	15	venous	venous	ADJ
dti-1424	31	16	graft	graft	NOUN
dti-1424	31	17	failure	failure	NOUN
dti-1424	31	18	in	in	ADP
dti-1424	31	19	relation	relation	NOUN
dti-1424	31	20	to	to	ADP
dti-1424	31	21	established	establish	VERB
dti-1424	31	22	risk	risk	NOUN
dti-1424	31	23	factors	factor	NOUN
dti-1424	31	24	for	for	ADP
dti-1424	31	25	atherosclerosis;13	atherosclerosis;13	ADJ
dti-1424	31	26	also	also	ADV
dti-1424	31	27	,	,	PUNCT
dti-1424	31	28	differences	difference	NOUN
dti-1424	31	29	in	in	ADP
dti-1424	31	30	thrombin	thrombin	NOUN
dti-1424	31	31	receptor	receptor	NOUN
dti-1424	31	32	expression	expression	NOUN
dti-1424	31	33	between	between	ADP
dti-1424	31	34	arterial	arterial	NOUN
dti-1424	31	35	and	and	CCONJ
dti-1424	31	36	venous	venous	ADJ
dti-1424	31	37	grafts	graft	NOUN
dti-1424	31	38	have	have	AUX
dti-1424	31	39	been	be	AUX
dti-1424	31	40	demonstrated,14	demonstrated,14	ADV
dti-1424	31	41	and	and	CCONJ
dti-1424	31	42	deregulation	deregulation	NOUN
dti-1424	31	43	of	of	ADP
dti-1424	31	44	these	these	DET
dti-1424	31	45	receptors	receptor	NOUN
dti-1424	31	46	has	have	AUX
dti-1424	31	47	been	be	AUX
dti-1424	31	48	associated	associate	VERB
dti-1424	31	49	with	with	ADP
dti-1424	31	50	in	in	ADP
dti-1424	31	51	-	-	PUNCT
dti-1424	31	52	stent	stent	NOUN
dti-1424	31	53	restenosis.15	restenosis.15	NOUN
dti-1424	31	54	nitric	nitric	ADJ
dti-1424	31	55	oxide	oxide	NOUN
dti-1424	31	56	production	production	NOUN
dti-1424	31	57	is	be	AUX
dti-1424	31	58	not	not	PART
dti-1424	31	59	reduced	reduce	VERB
dti-1424	31	60	in	in	ADP
dti-1424	31	61	arterial	arterial	ADJ
dti-1424	31	62	grafts	graft	NOUN
dti-1424	31	63	and	and	CCONJ
dti-1424	31	64	particularly	particularly	ADV
dti-1424	31	65	the	the	DET
dti-1424	31	66	ita	ita	NOUN
dti-1424	31	67	,	,	PUNCT
dti-1424	31	68	even	even	ADV
dti-1424	31	69	with	with	ADP
dti-1424	31	70	severe	severe	ADJ
dti-1424	31	71	atherosclerotic	atherosclerotic	ADJ
dti-1424	31	72	disease	disease	NOUN
dti-1424	31	73	,	,	PUNCT
dti-1424	31	74	and	and	CCONJ
dti-1424	31	75	this	this	PRON
dti-1424	31	76	is	be	AUX
dti-1424	31	77	thought	think	VERB
dti-1424	31	78	to	to	PART
dti-1424	31	79	be	be	AUX
dti-1424	31	80	one	one	NUM
dti-1424	31	81	of	of	ADP
dti-1424	31	82	the	the	DET
dti-1424	31	83	factors	factor	NOUN
dti-1424	31	84	in	in	ADP
dti-1424	31	85	the	the	DET
dti-1424	31	86	superior	superior	ADJ
dti-1424	31	87	outcome	outcome	NOUN
dti-1424	31	88	of	of	ADP
dti-1424	31	89	these	these	DET
dti-1424	31	90	conduits.16	conduits.16	NOUN
dti-1424	31	91	additionally	additionally	ADV
dti-1424	31	92	,	,	PUNCT
dti-1424	31	93	it	it	PRON
dti-1424	31	94	has	have	AUX
dti-1424	31	95	been	be	AUX
dti-1424	31	96	shown	show	VERB
dti-1424	31	97	that	that	SCONJ
dti-1424	31	98	the	the	DET
dti-1424	31	99	structure	structure	NOUN
dti-1424	31	100	of	of	ADP
dti-1424	31	101	the	the	DET
dti-1424	31	102	ita	ita	PROPN
dti-1424	31	103	itself	itself	PRON
dti-1424	31	104	is	be	AUX
dti-1424	31	105	able	able	ADJ
dti-1424	31	106	to	to	PART
dti-1424	31	107	better	well	ADV
dti-1424	31	108	adapt	adapt	VERB
dti-1424	31	109	to	to	ADP
dti-1424	31	110	arterial	arterial	ADJ
dti-1424	31	111	pressures	pressure	NOUN
dti-1424	31	112	and	and	CCONJ
dti-1424	31	113	its	its	PRON
dti-1424	31	114	endothelium	endothelium	NOUN
dti-1424	31	115	responds	respond	VERB
dti-1424	31	116	to	to	ADP
dti-1424	31	117	high	high	ADJ
dti-1424	31	118	flow	flow	NOUN
dti-1424	31	119	rates	rate	NOUN
dti-1424	31	120	with	with	ADP
dti-1424	31	121	a	a	DET
dti-1424	31	122	higher	high	ADJ
dti-1424	31	123	amount	amount	NOUN
dti-1424	31	124	of	of	ADP
dti-1424	31	125	nitric	nitric	ADJ
dti-1424	31	126	oxide	oxide	NOUN
dti-1424	31	127	,	,	PUNCT
dti-1424	31	128	providing	provide	VERB
dti-1424	31	129	superior	superior	ADJ
dti-1424	31	130	reactivity	reactivity	NOUN
dti-1424	31	131	to	to	PART
dti-1424	31	132	flow	flow	VERB
dti-1424	31	133	requirements	requirement	NOUN
dti-1424	31	134	in	in	ADP
dti-1424	31	135	the	the	DET
dti-1424	31	136	coronary	coronary	ADJ
dti-1424	31	137	arteries	artery	NOUN
dti-1424	31	138	when	when	SCONJ
dti-1424	31	139	used	use	VERB
dti-1424	31	140	as	as	ADP
dti-1424	31	141	a	a	DET
dti-1424	31	142	graft	graft	NOUN
dti-1424	31	143	in	in	ADP
dti-1424	31	144	cabg.17	cabg.17	PROPN
dti-1424	31	145	on	on	ADP
dti-1424	31	146	this	this	DET
dti-1424	31	147	basis	basis	NOUN
dti-1424	31	148	,	,	PUNCT
dti-1424	31	149	ita	ita	PROPN
dti-1424	31	150	might	might	AUX
dti-1424	31	151	be	be	AUX
dti-1424	31	152	considered	consider	VERB
dti-1424	31	153	as	as	ADP
dti-1424	31	154	a	a	DET
dti-1424	31	155	“	"	PUNCT
dti-1424	31	156	drugeluting	drugeluting	ADJ
dti-1424	31	157	”	"	PUNCT
dti-1424	31	158	graft	graft	NOUN
dti-1424	31	159	as	as	SCONJ
dti-1424	31	160	it	it	PRON
dti-1424	31	161	is	be	AUX
dti-1424	31	162	able	able	ADJ
dti-1424	31	163	to	to	PART
dti-1424	31	164	release	release	VERB
dti-1424	31	165	into	into	ADP
dti-1424	31	166	the	the	DET
dti-1424	31	167	grafted	graft	VERB
dti-1424	31	168	myocardium	myocardium	ADJ
dti-1424	31	169	nitric	nitric	ADJ
dti-1424	31	170	oxide	oxide	NOUN
dti-1424	31	171	,	,	PUNCT
dti-1424	31	172	providing	provide	VERB
dti-1424	31	173	important	important	ADJ
dti-1424	31	174	signaling	signal	VERB
dti-1424	31	175	to	to	PART
dti-1424	31	176	prevent	prevent	VERB
dti-1424	31	177	graft	graft	NOUN
dti-1424	31	178	failure	failure	NOUN
dti-1424	31	179	and	and	CCONJ
dti-1424	31	180	ameliorate	ameliorate	VERB
dti-1424	31	181	cardiac	cardiac	ADJ
dti-1424	31	182	function	function	NOUN
dti-1424	31	183	.	.	PUNCT
dti-1424	32	1	clearly	clearly	ADV
dti-1424	32	2	,	,	PUNCT
dti-1424	32	3	the	the	DET
dti-1424	32	4	biology	biology	NOUN
dti-1424	32	5	underlying	underlie	VERB
dti-1424	32	6	this	this	DET
dti-1424	32	7	process	process	NOUN
dti-1424	32	8	is	be	AUX
dti-1424	32	9	far	far	ADV
dti-1424	32	10	more	more	ADV
dti-1424	32	11	complex	complex	ADJ
dti-1424	32	12	and	and	CCONJ
dti-1424	32	13	is	be	AUX
dti-1424	32	14	not	not	PART
dti-1424	32	15	restricted	restrict	VERB
dti-1424	32	16	to	to	ADP
dti-1424	32	17	a	a	DET
dti-1424	32	18	single	single	ADJ
dti-1424	32	19	compound	compound	NOUN
dti-1424	32	20	,	,	PUNCT
dti-1424	32	21	but	but	CCONJ
dti-1424	32	22	most	most	ADJ
dti-1424	32	23	probably	probably	ADV
dti-1424	32	24	involves	involve	VERB
dti-1424	32	25	a	a	DET
dti-1424	32	26	wide	wide	ADJ
dti-1424	32	27	spectrum	spectrum	NOUN
dti-1424	32	28	of	of	ADP
dti-1424	32	29	molecules	molecule	NOUN
dti-1424	32	30	interacting	interact	VERB
dti-1424	32	31	to	to	PART
dti-1424	32	32	determine	determine	VERB
dti-1424	32	33	the	the	DET
dti-1424	32	34	biological	biological	ADJ
dti-1424	32	35	effects	effect	NOUN
dti-1424	32	36	seen	see	VERB
dti-1424	32	37	both	both	PRON
dti-1424	32	38	experimentally	experimentally	ADV
dti-1424	32	39	and	and	CCONJ
dti-1424	32	40	clinically	clinically	ADV
dti-1424	32	41	.	.	PUNCT
dti-1424	33	1	proteomics	proteomic	NOUN
dti-1424	33	2	studies	study	NOUN
dti-1424	33	3	allow	allow	VERB
dti-1424	33	4	for	for	ADP
dti-1424	33	5	a	a	DET
dti-1424	33	6	comprehensive	comprehensive	ADJ
dti-1424	33	7	analysis	analysis	NOUN
dti-1424	33	8	and	and	CCONJ
dti-1424	33	9	identification	identification	NOUN
dti-1424	33	10	of	of	ADP
dti-1424	33	11	the	the	DET
dti-1424	33	12	complete	complete	ADJ
dti-1424	33	13	protein	protein	NOUN
dti-1424	33	14	pattern	pattern	NOUN
dti-1424	33	15	of	of	ADP
dti-1424	33	16	a	a	DET
dti-1424	33	17	tissue	tissue	NOUN
dti-1424	33	18	or	or	CCONJ
dti-1424	33	19	fluid,18,19	fluid,18,19	NOUN
dti-1424	33	20	and	and	CCONJ
dti-1424	33	21	some	some	DET
dti-1424	33	22	studies	study	NOUN
dti-1424	33	23	performed	perform	VERB
dti-1424	33	24	using	use	VERB
dti-1424	33	25	this	this	DET
dti-1424	33	26	approach	approach	NOUN
dti-1424	33	27	showed	show	VERB
dti-1424	33	28	the	the	DET
dti-1424	33	29	presence	presence	NOUN
dti-1424	33	30	in	in	ADP
dti-1424	33	31	human	human	ADJ
dti-1424	33	32	arterial	arterial	NOUN
dti-1424	33	33	smooth	smooth	ADJ
dti-1424	33	34	muscle	muscle	NOUN
dti-1424	33	35	of	of	ADP
dti-1424	33	36	small	small	ADJ
dti-1424	33	37	leucine	leucine	NOUN
dti-1424	33	38	-	-	PUNCT
dti-1424	33	39	rich	rich	ADJ
dti-1424	33	40	proteoglycans	proteoglycan	NOUN
dti-1424	33	41	involved	involve	VERB
dti-1424	33	42	in	in	ADP
dti-1424	33	43	collagen	collagen	NOUN
dti-1424	33	44	fibrillogenesis	fibrillogenesis	PROPN
dti-1424	33	45	,	,	PUNCT
dti-1424	33	46	and	and	CCONJ
dti-1424	33	47	of	of	ADP
dti-1424	33	48	some	some	DET
dti-1424	33	49	non	non	ADJ
dti-1424	33	50	-	-	ADJ
dti-1424	33	51	fibrillar	fibrillar	ADJ
dti-1424	33	52	collagens	collagen	NOUN
dti-1424	33	53	in	in	ADP
dti-1424	33	54	combination	combination	NOUN
dti-1424	33	55	with	with	ADP
dti-1424	33	56	alterations	alteration	NOUN
dti-1424	33	57	of	of	ADP
dti-1424	33	58	several	several	ADJ
dti-1424	33	59	other	other	ADJ
dti-1424	33	60	proteins	protein	NOUN
dti-1424	33	61	.	.	PUNCT
dti-1424	34	1	this	this	PRON
dti-1424	34	2	has	have	AUX
dti-1424	34	3	been	be	AUX
dti-1424	34	4	considered	consider	VERB
dti-1424	34	5	as	as	ADP
dti-1424	34	6	a	a	DET
dti-1424	34	7	marker	marker	NOUN
dti-1424	34	8	of	of	ADP
dti-1424	34	9	arterial	arterial	ADJ
dti-1424	34	10	stiffness	stiffness	NOUN
dti-1424	34	11	and	and	CCONJ
dti-1424	34	12	therefore	therefore	ADV
dti-1424	34	13	increased	increase	VERB
dti-1424	34	14	risk	risk	NOUN
dti-1424	34	15	of	of	ADP
dti-1424	34	16	developing	develop	VERB
dti-1424	34	17	atherosclerosis.20	atherosclerosis.20	PROPN
dti-1424	34	18	structural	structural	ADJ
dti-1424	34	19	proteomic	proteomic	ADJ
dti-1424	34	20	studies	study	NOUN
dti-1424	34	21	on	on	ADP
dti-1424	34	22	ita	ita	PROPN
dti-1424	34	23	tissue	tissue	NOUN
dti-1424	34	24	showed	show	VERB
dti-1424	34	25	differential	differential	ADJ
dti-1424	34	26	expression	expression	NOUN
dti-1424	34	27	of	of	ADP
dti-1424	34	28	proteins	protein	NOUN
dti-1424	34	29	that	that	PRON
dti-1424	34	30	are	be	AUX
dti-1424	34	31	implicated	implicate	VERB
dti-1424	34	32	in	in	ADP
dti-1424	34	33	cytoskeleton	cytoskeleton	NOUN
dti-1424	34	34	activity	activity	NOUN
dti-1424	34	35	regulation,21	regulation,21	NOUN
dti-1424	34	36	in	in	ADP
dti-1424	34	37	the	the	DET
dti-1424	34	38	migrative	migrative	ADJ
dti-1424	34	39	capacity	capacity	NOUN
dti-1424	34	40	of	of	ADP
dti-1424	34	41	vascular	vascular	ADJ
dti-1424	34	42	smooth	smooth	ADJ
dti-1424	34	43	muscle	muscle	NOUN
dti-1424	34	44	cells	cell	NOUN
dti-1424	34	45	,	,	PUNCT
dti-1424	34	46	extracellular	extracellular	ADJ
dti-1424	34	47	matrix	matrix	NOUN
dti-1424	34	48	composition	composition	NOUN
dti-1424	34	49	,	,	PUNCT
dti-1424	34	50	coagulation	coagulation	NOUN
dti-1424	34	51	,	,	PUNCT
dti-1424	34	52	apoptosis	apoptosis	NOUN
dti-1424	34	53	,	,	PUNCT
dti-1424	34	54	and	and	CCONJ
dti-1424	34	55	heat	heat	NOUN
dti-1424	34	56	shock	shock	NOUN
dti-1424	34	57	response.22	response.22	NOUN
dti-1424	34	58	interestingly	interestingly	ADV
dti-1424	34	59	,	,	PUNCT
dti-1424	34	60	a	a	DET
dti-1424	34	61	proteomic	proteomic	ADJ
dti-1424	34	62	analysis	analysis	NOUN
dti-1424	34	63	of	of	ADP
dti-1424	34	64	the	the	DET
dti-1424	34	65	secrete	secrete	NOUN
dti-1424	34	66	of	of	ADP
dti-1424	34	67	ita	ita	PROPN
dti-1424	34	68	,	,	PUNCT
dti-1424	34	69	known	know	VERB
dti-1424	34	70	as	as	ADP
dti-1424	34	71	secretome	secretome	NOUN
dti-1424	34	72	,	,	PUNCT
dti-1424	34	73	demonstrated	demonstrate	VERB
dti-1424	34	74	an	an	DET
dti-1424	34	75	increased	increase	VERB
dti-1424	34	76	production	production	NOUN
dti-1424	34	77	of	of	ADP
dti-1424	34	78	gelsolin	gelsolin	PROPN
dti-1424	34	79	,	,	PUNCT
dti-1424	34	80	vinculin	vinculin	PROPN
dti-1424	34	81	,	,	PUNCT
dti-1424	34	82	lamin	lamin	VERB
dti-1424	34	83	a	a	DET
dti-1424	34	84	/	/	SYM
dti-1424	34	85	c	c	NOUN
dti-1424	34	86	and	and	CCONJ
dti-1424	34	87	phosphoglucomutase	phosphoglucomutase	NOUN
dti-1424	34	88	5	5	NUM
dti-1424	34	89	by	by	ADP
dti-1424	34	90	mammary	mammary	ADJ
dti-1424	34	91	arterial	arterial	ADJ
dti-1424	34	92	tissues	tissue	NOUN
dti-1424	34	93	.	.	PUNCT
dti-1424	35	1	these	these	DET
dti-1424	35	2	proteins	protein	NOUN
dti-1424	35	3	are	be	AUX
dti-1424	35	4	also	also	ADV
dti-1424	35	5	involved	involve	VERB
dti-1424	35	6	in	in	ADP
dti-1424	35	7	the	the	DET
dti-1424	35	8	regulation	regulation	NOUN
dti-1424	35	9	of	of	ADP
dti-1424	35	10	important	important	ADJ
dti-1424	35	11	intracellular	intracellular	ADJ
dti-1424	35	12	mechanisms	mechanism	NOUN
dti-1424	35	13	related	relate	VERB
dti-1424	35	14	to	to	ADP
dti-1424	35	15	cell	cell	NOUN
dti-1424	35	16	migration	migration	NOUN
dti-1424	35	17	,	,	PUNCT
dti-1424	35	18	ecm	ecm	NOUN
dti-1424	35	19	deposition	deposition	NOUN
dti-1424	35	20	and	and	CCONJ
dti-1424	35	21	smooth	smooth	ADJ
dti-1424	35	22	muscle	muscle	NOUN
dti-1424	35	23	phenotype	phenotype	NOUN
dti-1424	35	24	switching	switching	NOUN
dti-1424	35	25	,	,	PUNCT
dti-1424	35	26	which	which	PRON
dti-1424	35	27	are	be	AUX
dti-1424	35	28	crucial	crucial	ADJ
dti-1424	35	29	steps	step	NOUN
dti-1424	35	30	in	in	ADP
dti-1424	35	31	atherosclerosis	atherosclerosis	NOUN
dti-1424	35	32	pathogenesis.23	pathogenesis.23	ADP
dti-1424	35	33	the	the	DET
dti-1424	35	34	expression	expression	NOUN
dti-1424	35	35	of	of	ADP
dti-1424	35	36	specific	specific	ADJ
dti-1424	35	37	groups	group	NOUN
dti-1424	35	38	of	of	ADP
dti-1424	35	39	proteins	protein	NOUN
dti-1424	35	40	in	in	ADP
dti-1424	35	41	the	the	DET
dti-1424	35	42	ita	ita	NOUN
dti-1424	35	43	is	be	AUX
dti-1424	35	44	claimed	claim	VERB
dti-1424	35	45	to	to	PART
dti-1424	35	46	be	be	AUX
dti-1424	35	47	the	the	DET
dti-1424	35	48	basis	basis	NOUN
dti-1424	35	49	of	of	ADP
dti-1424	35	50	the	the	DET
dti-1424	35	51	relative	relative	ADJ
dti-1424	35	52	protection	protection	NOUN
dti-1424	35	53	of	of	ADP
dti-1424	35	54	this	this	DET
dti-1424	35	55	vessel	vessel	NOUN
dti-1424	35	56	from	from	ADP
dti-1424	35	57	the	the	DET
dti-1424	35	58	onset	onset	NOUN
dti-1424	35	59	and	and	CCONJ
dti-1424	35	60	progression	progression	NOUN
dti-1424	35	61	of	of	ADP
dti-1424	35	62	atherosclerosis	atherosclerosis	NOUN
dti-1424	35	63	,	,	PUNCT
dti-1424	35	64	and	and	CCONJ
dti-1424	35	65	subsequently	subsequently	ADV
dti-1424	35	66	of	of	ADP
dti-1424	35	67	its	its	PRON
dti-1424	35	68	beneficial	beneficial	ADJ
dti-1424	35	69	effects	effect	NOUN
dti-1424	35	70	when	when	SCONJ
dti-1424	35	71	is	be	AUX
dti-1424	35	72	used	use	VERB
dti-1424	35	73	as	as	ADP
dti-1424	35	74	a	a	DET
dti-1424	35	75	graft	graft	NOUN
dti-1424	35	76	for	for	ADP
dti-1424	35	77	coronary	coronary	ADJ
dti-1424	35	78	artery	artery	NOUN
dti-1424	35	79	in	in	ADP
dti-1424	35	80	terms	term	NOUN
dti-1424	35	81	of	of	ADP
dti-1424	35	82	recurrence	recurrence	NOUN
dti-1424	35	83	of	of	ADP
dti-1424	35	84	heart	heart	NOUN
dti-1424	35	85	disease.22,23	disease.22,23	NOUN
dti-1424	35	86	from	from	ADP
dti-1424	35	87	these	these	DET
dti-1424	35	88	studies	study	NOUN
dti-1424	35	89	,	,	PUNCT
dti-1424	35	90	we	we	PRON
dti-1424	35	91	might	might	AUX
dti-1424	35	92	reliably	reliably	ADV
dti-1424	35	93	speculate	speculate	VERB
dti-1424	35	94	that	that	SCONJ
dti-1424	35	95	when	when	SCONJ
dti-1424	35	96	used	use	VERB
dti-1424	35	97	in	in	ADP
dti-1424	35	98	the	the	DET
dti-1424	35	99	context	context	NOUN
dti-1424	35	100	of	of	ADP
dti-1424	35	101	cabg	cabg	NOUN
dti-1424	35	102	,	,	PUNCT
dti-1424	35	103	the	the	DET
dti-1424	35	104	ita	ita	PROPN
dti-1424	35	105	exerts	exert	VERB
dti-1424	35	106	a	a	DET
dti-1424	35	107	“	"	PUNCT
dti-1424	35	108	paracrine	paracrine	ADJ
dti-1424	35	109	activity	activity	NOUN
dti-1424	35	110	”	"	PUNCT
dti-1424	35	111	liberating	liberate	VERB
dti-1424	35	112	locally	locally	ADV
dti-1424	35	113	and	and	CCONJ
dti-1424	35	114	within	within	ADP
dti-1424	35	115	the	the	DET
dti-1424	35	116	blood	blood	NOUN
dti-1424	35	117	stream	stream	NOUN
dti-1424	35	118	factors	factor	NOUN
dti-1424	35	119	that	that	PRON
dti-1424	35	120	are	be	AUX
dti-1424	35	121	able	able	ADJ
dti-1424	35	122	to	to	PART
dti-1424	35	123	maintain	maintain	VERB
dti-1424	35	124	a	a	DET
dti-1424	35	125	positive	positive	ADJ
dti-1424	35	126	http://www.la-press.com/drug-target-insights-journal-j23	http://www.la-press.com/drug-target-insights-journal-j23	NOUN
dti-1424	35	127	http://www.la-press.com	http://www.la-press.com	X
dti-1424	35	128	drug	drug	NOUN
dti-1424	35	129	target	target	NOUN
dti-1424	35	130	insights	insight	NOUN
dti-1424	35	131	drug	drug	NOUN
dti-1424	35	132	target	target	NOUN
dti-1424	35	133	insights	insight	NOUN
dti-1424	35	134	2016:10(s1	2016:10(s1	NUM
dti-1424	35	135	)	)	PUNCT
dti-1424	35	136	17	17	NUM
dti-1424	35	137	vascular	vascular	ADJ
dti-1424	35	138	homeostasis	homeostasis	NOUN
dti-1424	35	139	,	,	PUNCT
dti-1424	35	140	thereby	thereby	ADV
dti-1424	35	141	avoiding	avoid	VERB
dti-1424	35	142	disease	disease	NOUN
dti-1424	35	143	recurrence	recurrence	NOUN
dti-1424	35	144	in	in	ADP
dti-1424	35	145	the	the	DET
dti-1424	35	146	grafted	graft	VERB
dti-1424	35	147	coronary	coronary	ADJ
dti-1424	35	148	and	and	CCONJ
dti-1424	35	149	permitting	permit	VERB
dti-1424	35	150	high	high	ADJ
dti-1424	35	151	patency	patency	NOUN
dti-1424	35	152	rate	rate	NOUN
dti-1424	35	153	of	of	ADP
dti-1424	35	154	the	the	DET
dti-1424	35	155	bypass	bypass	NOUN
dti-1424	35	156	in	in	ADP
dti-1424	35	157	the	the	DET
dti-1424	35	158	long	long	ADJ
dti-1424	35	159	term	term	NOUN
dti-1424	35	160	.	.	PUNCT
dti-1424	36	1	considering	consider	VERB
dti-1424	36	2	the	the	DET
dti-1424	36	3	significant	significant	ADJ
dti-1424	36	4	difference	difference	NOUN
dti-1424	36	5	in	in	ADP
dti-1424	36	6	patency	patency	NOUN
dti-1424	36	7	rate	rate	NOUN
dti-1424	36	8	when	when	SCONJ
dti-1424	36	9	conduits	conduit	NOUN
dti-1424	36	10	different	different	ADJ
dti-1424	36	11	from	from	ADP
dti-1424	36	12	ita	ita	PROPN
dti-1424	36	13	are	be	AUX
dti-1424	36	14	used	use	VERB
dti-1424	36	15	,	,	PUNCT
dti-1424	36	16	more	more	ADV
dti-1424	36	17	complex	complex	ADJ
dti-1424	36	18	mechanisms	mechanism	NOUN
dti-1424	36	19	should	should	AUX
dti-1424	36	20	be	be	AUX
dti-1424	36	21	underlying	underlie	VERB
dti-1424	36	22	ita	ita	NOUN
dti-1424	36	23	selective	selective	ADJ
dti-1424	36	24	advantage	advantage	NOUN
dti-1424	36	25	in	in	ADP
dti-1424	36	26	cabg	cabg	NOUN
dti-1424	36	27	.	.	PUNCT
dti-1424	37	1	use	use	NOUN
dti-1424	37	2	of	of	ADP
dti-1424	37	3	proteomics	proteomic	NOUN
dti-1424	37	4	and	and	CCONJ
dti-1424	37	5	redox	redox	NOUN
dti-1424	37	6	-	-	PUNCT
dti-1424	37	7	proteomics	proteomic	NOUN
dti-1424	37	8	approaches	approach	NOUN
dti-1424	37	9	to	to	PART
dti-1424	37	10	simultaneously	simultaneously	ADV
dti-1424	37	11	compare	compare	VERB
dti-1424	37	12	the	the	DET
dti-1424	37	13	protein	protein	NOUN
dti-1424	37	14	profile	profile	NOUN
dti-1424	37	15	of	of	ADP
dti-1424	37	16	ita	ita	PROPN
dti-1424	37	17	,	,	PUNCT
dti-1424	37	18	saphenous	saphenous	ADJ
dti-1424	37	19	vein	vein	ADJ
dti-1424	37	20	grafts	graft	NOUN
dti-1424	37	21	and	and	CCONJ
dti-1424	37	22	aorta	aorta	NOUN
dti-1424	37	23	,	,	PUNCT
dti-1424	37	24	another	another	DET
dti-1424	37	25	tissue	tissue	NOUN
dti-1424	37	26	prone	prone	ADJ
dti-1424	37	27	to	to	ADP
dti-1424	37	28	atherosclerosis	atherosclerosis	NOUN
dti-1424	37	29	,	,	PUNCT
dti-1424	37	30	has	have	AUX
dti-1424	37	31	been	be	AUX
dti-1424	37	32	advocated	advocate	VERB
dti-1424	37	33	to	to	PART
dti-1424	37	34	better	well	ADV
dti-1424	37	35	understand	understand	VERB
dti-1424	37	36	differences	difference	NOUN
dti-1424	37	37	among	among	ADP
dti-1424	37	38	the	the	DET
dti-1424	37	39	conduits	conduit	NOUN
dti-1424	37	40	.	.	PUNCT
dti-1424	38	1	also	also	ADV
dti-1424	38	2	,	,	PUNCT
dti-1424	38	3	these	these	DET
dti-1424	38	4	investigations	investigation	NOUN
dti-1424	38	5	might	might	AUX
dti-1424	38	6	be	be	AUX
dti-1424	38	7	extended	extend	VERB
dti-1424	38	8	to	to	ADP
dti-1424	38	9	the	the	DET
dti-1424	38	10	secretomes	secretome	NOUN
dti-1424	38	11	of	of	ADP
dti-1424	38	12	these	these	DET
dti-1424	38	13	conduits	conduit	NOUN
dti-1424	38	14	in	in	ADP
dti-1424	38	15	order	order	NOUN
dti-1424	38	16	to	to	PART
dti-1424	38	17	have	have	AUX
dti-1424	38	18	a	a	DET
dti-1424	38	19	paracrine	paracrine	NOUN
dti-1424	38	20	correlate	correlate	VERB
dti-1424	38	21	to	to	ADP
dti-1424	38	22	the	the	DET
dti-1424	38	23	targets	target	NOUN
dti-1424	38	24	found	find	VERB
dti-1424	38	25	in	in	ADP
dti-1424	38	26	the	the	DET
dti-1424	38	27	respective	respective	ADJ
dti-1424	38	28	tissues	tissue	NOUN
dti-1424	38	29	.	.	PUNCT
dti-1424	39	1	differential	differential	ADJ
dti-1424	39	2	profiles	profile	NOUN
dti-1424	39	3	of	of	ADP
dti-1424	39	4	protein	protein	NOUN
dti-1424	39	5	expression	expression	NOUN
dti-1424	39	6	exclusively	exclusively	ADV
dti-1424	39	7	present	present	ADJ
dti-1424	39	8	in	in	ADP
dti-1424	39	9	ita	ita	PROPN
dti-1424	39	10	tissues	tissue	NOUN
dti-1424	39	11	and	and	CCONJ
dti-1424	39	12	secrete	secrete	NOUN
dti-1424	39	13	,	,	PUNCT
dti-1424	39	14	but	but	CCONJ
dti-1424	39	15	not	not	PART
dti-1424	39	16	in	in	ADP
dti-1424	39	17	the	the	DET
dti-1424	39	18	other	other	ADJ
dti-1424	39	19	vessels	vessel	NOUN
dti-1424	39	20	,	,	PUNCT
dti-1424	39	21	have	have	AUX
dti-1424	39	22	been	be	AUX
dti-1424	39	23	intriguingly	intriguingly	ADV
dti-1424	39	24	discovered	discover	VERB
dti-1424	39	25	(	(	PUNCT
dti-1424	39	26	fig	fig	NOUN
dti-1424	39	27	.	.	PUNCT
dti-1424	39	28	 	 	SPACE
dti-1424	39	29	1	1	X
dti-1424	39	30	)	)	PUNCT
dti-1424	39	31	and	and	CCONJ
dti-1424	39	32	the	the	DET
dti-1424	39	33	identification	identification	NOUN
dti-1424	39	34	of	of	ADP
dti-1424	39	35	these	these	DET
dti-1424	39	36	proteins	protein	NOUN
dti-1424	39	37	would	would	AUX
dti-1424	39	38	provide	provide	VERB
dti-1424	39	39	in	in	ADP
dti-1424	39	40	the	the	DET
dti-1424	39	41	future	future	ADJ
dti-1424	39	42	precious	precious	ADJ
dti-1424	39	43	information	information	NOUN
dti-1424	39	44	to	to	PART
dti-1424	39	45	elucidate	elucidate	VERB
dti-1424	39	46	reasons	reason	NOUN
dti-1424	39	47	of	of	ADP
dti-1424	39	48	ita	ita	NOUN
dti-1424	39	49	superiority	superiority	NOUN
dti-1424	39	50	in	in	ADP
dti-1424	39	51	cabg	cabg	NOUN
dti-1424	39	52	.	.	PUNCT
dti-1424	40	1	moreover	moreover	ADV
dti-1424	40	2	,	,	PUNCT
dti-1424	40	3	the	the	DET
dti-1424	40	4	identification	identification	NOUN
dti-1424	40	5	of	of	ADP
dti-1424	40	6	these	these	DET
dti-1424	40	7	proteins	protein	NOUN
dti-1424	40	8	would	would	AUX
dti-1424	40	9	enable	enable	VERB
dti-1424	40	10	more	more	ADV
dti-1424	40	11	significant	significant	ADJ
dti-1424	40	12	clinical	clinical	ADJ
dti-1424	40	13	applications	application	NOUN
dti-1424	40	14	.	.	PUNCT
dti-1424	41	1	the	the	DET
dti-1424	41	2	factors	factor	NOUN
dti-1424	41	3	produced	produce	VERB
dti-1424	41	4	by	by	ADP
dti-1424	41	5	the	the	DET
dti-1424	41	6	ita	ita	NOUN
dti-1424	41	7	,	,	PUNCT
dti-1424	41	8	and	and	CCONJ
dti-1424	41	9	considered	consider	VERB
dti-1424	41	10	at	at	ADP
dti-1424	41	11	the	the	DET
dti-1424	41	12	basis	basis	NOUN
dti-1424	41	13	of	of	ADP
dti-1424	41	14	the	the	DET
dti-1424	41	15	maintenance	maintenance	NOUN
dti-1424	41	16	of	of	ADP
dti-1424	41	17	graft	graft	NOUN
dti-1424	41	18	patency	patency	NOUN
dti-1424	41	19	and	and	CCONJ
dti-1424	41	20	protection	protection	NOUN
dti-1424	41	21	from	from	ADP
dti-1424	41	22	atherosclerosis	atherosclerosis	NOUN
dti-1424	41	23	recurrence	recurrence	NOUN
dti-1424	41	24	,	,	PUNCT
dti-1424	41	25	might	might	AUX
dti-1424	41	26	constitute	constitute	VERB
dti-1424	41	27	in	in	ADP
dti-1424	41	28	the	the	DET
dti-1424	41	29	future	future	ADJ
dti-1424	41	30	“	"	PUNCT
dti-1424	41	31	drugs	drug	NOUN
dti-1424	41	32	”	"	PUNCT
dti-1424	41	33	to	to	PART
dti-1424	41	34	be	be	AUX
dti-1424	41	35	administered	administer	VERB
dti-1424	41	36	to	to	ADP
dti-1424	41	37	patients	patient	NOUN
dti-1424	41	38	or	or	CCONJ
dti-1424	41	39	eluted	elute	VERB
dti-1424	41	40	in	in	ADP
dti-1424	41	41	stents	stent	NOUN
dti-1424	41	42	or	or	CCONJ
dti-1424	41	43	delivery	delivery	NOUN
dti-1424	41	44	devices	device	NOUN
dti-1424	41	45	.	.	PUNCT
dti-1424	42	1	conversely	conversely	ADV
dti-1424	42	2	,	,	PUNCT
dti-1424	42	3	factors	factor	NOUN
dti-1424	42	4	identified	identify	VERB
dti-1424	42	5	from	from	ADP
dti-1424	42	6	saphenous	saphenous	ADJ
dti-1424	42	7	tissue	tissue	NOUN
dti-1424	42	8	,	,	PUNCT
dti-1424	42	9	which	which	PRON
dti-1424	42	10	are	be	AUX
dti-1424	42	11	clinically	clinically	ADV
dti-1424	42	12	associated	associate	VERB
dti-1424	42	13	to	to	ADP
dti-1424	42	14	poor	poor	ADJ
dti-1424	42	15	outcomes	outcome	NOUN
dti-1424	42	16	and	and	CCONJ
dti-1424	42	17	failure	failure	NOUN
dti-1424	42	18	of	of	ADP
dti-1424	42	19	the	the	DET
dti-1424	42	20	grafts	graft	NOUN
dti-1424	42	21	,	,	PUNCT
dti-1424	42	22	might	might	AUX
dti-1424	42	23	represent	represent	VERB
dti-1424	42	24	targets	target	NOUN
dti-1424	42	25	for	for	ADP
dti-1424	42	26	design	design	NOUN
dti-1424	42	27	of	of	ADP
dti-1424	42	28	specific	specific	ADJ
dti-1424	42	29	compounds	compound	NOUN
dti-1424	42	30	with	with	ADP
dti-1424	42	31	inhibitory	inhibitory	ADJ
dti-1424	42	32	or	or	CCONJ
dti-1424	42	33	blocking	blocking	NOUN
dti-1424	42	34	effects	effect	NOUN
dti-1424	42	35	.	.	PUNCT
dti-1424	43	1	in	in	ADP
dti-1424	43	2	the	the	DET
dti-1424	43	3	field	field	NOUN
dti-1424	43	4	of	of	ADP
dti-1424	43	5	drug	drug	NOUN
dti-1424	43	6	-	-	PUNCT
dti-1424	43	7	eluting	elute	VERB
dti-1424	43	8	devices	device	NOUN
dti-1424	43	9	,	,	PUNCT
dti-1424	43	10	a	a	DET
dti-1424	43	11	close	close	ADJ
dti-1424	43	12	observation	observation	NOUN
dti-1424	43	13	and	and	CCONJ
dti-1424	43	14	attention	attention	NOUN
dti-1424	43	15	to	to	ADP
dti-1424	43	16	the	the	DET
dti-1424	43	17	naturally	naturally	ADV
dti-1424	43	18	occurring	occur	VERB
dti-1424	43	19	phenomena	phenomenon	NOUN
dti-1424	43	20	might	might	AUX
dti-1424	43	21	provide	provide	VERB
dti-1424	43	22	us	we	PRON
dti-1424	43	23	with	with	ADP
dti-1424	43	24	a	a	DET
dti-1424	43	25	range	range	NOUN
dti-1424	43	26	of	of	ADP
dti-1424	43	27	therapeutic	therapeutic	ADJ
dti-1424	43	28	options	option	NOUN
dti-1424	43	29	wider	wide	ADJ
dti-1424	43	30	than	than	ADP
dti-1424	43	31	any	any	DET
dti-1424	43	32	other	other	ADJ
dti-1424	43	33	drug	drug	NOUN
dti-1424	43	34	currently	currently	ADV
dti-1424	43	35	used	use	VERB
dti-1424	43	36	in	in	ADP
dti-1424	43	37	des	de	NOUN
dti-1424	43	38	or	or	CCONJ
dti-1424	43	39	tissue	tissue	NOUN
dti-1424	43	40	engineering	engineering	NOUN
dti-1424	43	41	approaches	approach	NOUN
dti-1424	43	42	.	.	PUNCT
dti-1424	44	1	for	for	ADP
dti-1424	44	2	example	example	NOUN
dti-1424	44	3	,	,	PUNCT
dti-1424	44	4	the	the	DET
dti-1424	44	5	ita	ita	PROPN
dti-1424	44	6	naturally	naturally	ADV
dti-1424	44	7	carries	carry	VERB
dti-1424	44	8	a	a	DET
dti-1424	44	9	regulated	regulated	ADJ
dti-1424	44	10	set	set	NOUN
dti-1424	44	11	of	of	ADP
dti-1424	44	12	factors	factor	NOUN
dti-1424	44	13	,	,	PUNCT
dti-1424	44	14	finely	finely	ADV
dti-1424	44	15	modulated	modulate	VERB
dti-1424	44	16	and	and	CCONJ
dti-1424	44	17	intertwined	intertwine	VERB
dti-1424	44	18	,	,	PUNCT
dti-1424	44	19	which	which	PRON
dti-1424	44	20	protects	protect	VERB
dti-1424	44	21	against	against	ADP
dti-1424	44	22	atherosclerosis	atherosclerosis	NOUN
dti-1424	44	23	and	and	CCONJ
dti-1424	44	24	can	can	AUX
dti-1424	44	25	be	be	AUX
dti-1424	44	26	therefore	therefore	ADV
dti-1424	44	27	considered	consider	VERB
dti-1424	44	28	the	the	DET
dti-1424	44	29	best	good	ADJ
dti-1424	44	30	drug	drug	NOUN
dti-1424	44	31	-	-	PUNCT
dti-1424	44	32	eluting	elute	VERB
dti-1424	44	33	device	device	NOUN
dti-1424	44	34	available	available	ADJ
dti-1424	44	35	at	at	ADP
dti-1424	44	36	the	the	DET
dti-1424	44	37	moment	moment	NOUN
dti-1424	44	38	in	in	ADP
dti-1424	44	39	cardiovascular	cardiovascular	ADJ
dti-1424	44	40	disease	disease	NOUN
dti-1424	44	41	.	.	PUNCT
dti-1424	45	1	in	in	ADP
dti-1424	45	2	conclusion	conclusion	NOUN
dti-1424	45	3	,	,	PUNCT
dti-1424	45	4	with	with	ADP
dti-1424	45	5	the	the	DET
dti-1424	45	6	increase	increase	NOUN
dti-1424	45	7	in	in	ADP
dti-1424	45	8	life	life	NOUN
dti-1424	45	9	expectancy	expectancy	NOUN
dti-1424	45	10	and	and	CCONJ
dti-1424	45	11	in	in	ADP
dti-1424	45	12	the	the	DET
dti-1424	45	13	morbidities	morbidity	NOUN
dti-1424	45	14	related	relate	VERB
dti-1424	45	15	to	to	ADP
dti-1424	45	16	chronic	chronic	ADJ
dti-1424	45	17	diseases	disease	NOUN
dti-1424	45	18	,	,	PUNCT
dti-1424	45	19	smarter	smart	ADJ
dti-1424	45	20	weapons	weapon	NOUN
dti-1424	45	21	are	be	AUX
dti-1424	45	22	required	require	VERB
dti-1424	45	23	to	to	PART
dti-1424	45	24	control	control	VERB
dti-1424	45	25	pathology	pathology	NOUN
dti-1424	45	26	.	.	PUNCT
dti-1424	46	1	the	the	DET
dti-1424	46	2	exciting	exciting	ADJ
dti-1424	46	3	field	field	NOUN
dti-1424	46	4	of	of	ADP
dti-1424	46	5	drug	drug	NOUN
dti-1424	46	6	delivery	delivery	NOUN
dti-1424	46	7	devices	device	NOUN
dti-1424	46	8	might	might	AUX
dti-1424	46	9	provide	provide	VERB
dti-1424	46	10	novel	novel	ADJ
dti-1424	46	11	strategies	strategy	NOUN
dti-1424	46	12	and	and	CCONJ
dti-1424	46	13	open	open	VERB
dti-1424	46	14	new	new	ADJ
dti-1424	46	15	avenues	avenue	NOUN
dti-1424	46	16	in	in	ADP
dti-1424	46	17	the	the	DET
dti-1424	46	18	treatment	treatment	NOUN
dti-1424	46	19	of	of	ADP
dti-1424	46	20	cardiovascular	cardiovascular	ADJ
dti-1424	46	21	disease	disease	NOUN
dti-1424	46	22	.	.	PUNCT
dti-1424	47	1	in	in	ADP
dti-1424	47	2	this	this	DET
dti-1424	47	3	context	context	NOUN
dti-1424	47	4	,	,	PUNCT
dti-1424	47	5	scientists	scientist	NOUN
dti-1424	47	6	might	might	AUX
dti-1424	47	7	need	need	VERB
dti-1424	47	8	to	to	PART
dti-1424	47	9	realize	realize	VERB
dti-1424	47	10	that	that	SCONJ
dti-1424	47	11	the	the	DET
dti-1424	47	12	endogenous	endogenous	ADJ
dti-1424	47	13	and	and	CCONJ
dti-1424	47	14	physiologically	physiologically	ADV
dti-1424	47	15	-	-	PUNCT
dti-1424	47	16	occurring	occur	VERB
dti-1424	47	17	release	release	NOUN
dti-1424	47	18	of	of	ADP
dti-1424	47	19	paracrine	paracrine	NOUN
dti-1424	47	20	factors	factor	NOUN
dti-1424	47	21	by	by	ADP
dti-1424	47	22	the	the	DET
dti-1424	47	23	native	native	ADJ
dti-1424	47	24	tissues	tissue	NOUN
dti-1424	47	25	might	might	AUX
dti-1424	47	26	be	be	AUX
dti-1424	47	27	a	a	DET
dti-1424	47	28	“	"	PUNCT
dti-1424	47	29	system	system	NOUN
dti-1424	47	30	”	"	PUNCT
dti-1424	47	31	to	to	PART
dti-1424	47	32	better	well	ADV
dti-1424	47	33	understand	understand	VERB
dti-1424	47	34	and	and	CCONJ
dti-1424	47	35	to	to	PART
dti-1424	47	36	target	target	VERB
dti-1424	47	37	when	when	SCONJ
dti-1424	47	38	constructing	construct	VERB
dti-1424	47	39	new	new	ADJ
dti-1424	47	40	drug	drug	NOUN
dti-1424	47	41	-	-	PUNCT
dti-1424	47	42	releasing	release	VERB
dti-1424	47	43	devices	device	NOUN
dti-1424	47	44	.	.	PUNCT
dti-1424	48	1	references	reference	NOUN
dti-1424	48	2	1	1	NUM
dti-1424	48	3	.	.	PUNCT
dti-1424	48	4	spadaccio	spadaccio	PROPN
dti-1424	48	5	c	c	PROPN
dti-1424	48	6	,	,	PUNCT
dti-1424	48	7	nappi	nappi	PROPN
dti-1424	48	8	f	f	PROPN
dti-1424	48	9	,	,	PUNCT
dti-1424	48	10	al	al	PROPN
dti-1424	48	11	-	-	PUNCT
dti-1424	48	12	attar	attar	PROPN
dti-1424	48	13	n	n	PROPN
dti-1424	48	14	,	,	PUNCT
dti-1424	48	15	et	et	PROPN
dti-1424	48	16	al	al	PROPN
dti-1424	48	17	.	.	PROPN
dti-1424	48	18	old	old	ADJ
dti-1424	48	19	myths	myth	NOUN
dti-1424	48	20	,	,	PUNCT
dti-1424	48	21	new	new	ADJ
dti-1424	48	22	concerns	concern	NOUN
dti-1424	48	23	:	:	PUNCT
dti-1424	48	24	the	the	DET
dti-1424	48	25	longterm	longterm	ADJ
dti-1424	48	26	effects	effect	NOUN
dti-1424	48	27	of	of	ADP
dti-1424	48	28	ascending	ascend	VERB
dti-1424	48	29	aorta	aorta	NOUN
dti-1424	48	30	replacement	replacement	NOUN
dti-1424	48	31	with	with	ADP
dti-1424	48	32	dacron	dacron	NOUN
dti-1424	48	33	grafts	graft	NOUN
dti-1424	48	34	.	.	PUNCT
dti-1424	49	1	not	not	PART
dti-1424	49	2	all	all	PRON
dti-1424	49	3	that	that	PRON
dti-1424	49	4	glitters	glitter	NOUN
dti-1424	49	5	is	be	AUX
dti-1424	49	6	gold	gold	NOUN
dti-1424	49	7	.	.	PUNCT
dti-1424	50	1	j	j	PROPN
dti-1424	50	2	cardiovasc	cardiovasc	PROPN
dti-1424	50	3	transl	transl	PROPN
dti-1424	50	4	res	re	NOUN
dti-1424	50	5	.	.	PUNCT
dti-1424	51	1	2016;9(4):334–342	2016;9(4):334–342	NUM
dti-1424	51	2	.	.	NOUN
dti-1424	51	3	2	2	NUM
dti-1424	51	4	.	.	X
dti-1424	51	5	nappi	nappi	PROPN
dti-1424	51	6	f	f	PROPN
dti-1424	51	7	,	,	PUNCT
dti-1424	51	8	spadaccio	spadaccio	PROPN
dti-1424	51	9	c	c	NOUN
dti-1424	51	10	,	,	PUNCT
dti-1424	51	11	fraldi	fraldi	X
dti-1424	51	12	m	m	PROPN
dti-1424	51	13	,	,	PUNCT
dti-1424	51	14	et	et	PROPN
dti-1424	51	15	al	al	PROPN
dti-1424	51	16	.	.	PUNCT
dti-1424	52	1	a	a	DET
dti-1424	52	2	composite	composite	ADJ
dti-1424	52	3	semiresorbable	semiresorbable	ADJ
dti-1424	52	4	armoured	armoured	ADJ
dti-1424	52	5	scaffold	scaffold	NOUN
dti-1424	52	6	stabilizes	stabilize	VERB
dti-1424	52	7	pulmonary	pulmonary	ADJ
dti-1424	52	8	autograft	autograft	NOUN
dti-1424	52	9	after	after	ADP
dti-1424	52	10	the	the	DET
dti-1424	52	11	ross	ross	PROPN
dti-1424	52	12	operation	operation	NOUN
dti-1424	52	13	:	:	PUNCT
dti-1424	52	14	mr	mr	PROPN
dti-1424	52	15	ross	ross	PROPN
dti-1424	52	16	’s	’s	PART
dti-1424	52	17	dream	dream	NOUN
dti-1424	52	18	fulfilled	fulfil	VERB
dti-1424	52	19	.	.	PUNCT
dti-1424	53	1	j	j	PROPN
dti-1424	53	2	thorac	thorac	PROPN
dti-1424	53	3	cardiovasc	cardiovasc	PROPN
dti-1424	53	4	surg	surg	PROPN
dti-1424	53	5	.	.	PUNCT
dti-1424	54	1	2016;151(1):155–164	2016;151(1):155–164	NUM
dti-1424	54	2	e151	e151	NUM
dti-1424	54	3	.	.	PROPN
dti-1424	54	4	3	3	NUM
dti-1424	54	5	.	.	NOUN
dti-1424	54	6	spadaccio	spadaccio	PROPN
dti-1424	54	7	c	c	PROPN
dti-1424	54	8	,	,	PUNCT
dti-1424	54	9	montagnani	montagnani	PROPN
dti-1424	54	10	s	s	PART
dti-1424	54	11	,	,	PUNCT
dti-1424	54	12	acar	acar	VERB
dti-1424	54	13	c	c	NOUN
dti-1424	54	14	,	,	PUNCT
dti-1424	54	15	nappi	nappi	PROPN
dti-1424	54	16	f.	f.	PROPN
dti-1424	54	17	introducing	introduce	VERB
dti-1424	54	18	bioresorbable	bioresorbable	ADJ
dti-1424	54	19	scaffolds	scaffold	NOUN
dti-1424	54	20	into	into	ADP
dti-1424	54	21	the	the	DET
dti-1424	54	22	show	show	NOUN
dti-1424	54	23	.	.	PUNCT
dti-1424	55	1	a	a	DET
dti-1424	55	2	potential	potential	NOUN
dti-1424	55	3	adjunct	adjunct	VERB
dti-1424	55	4	to	to	PART
dti-1424	55	5	resuscitate	resuscitate	VERB
dti-1424	55	6	ross	ross	PROPN
dti-1424	55	7	procedure	procedure	NOUN
dti-1424	55	8	.	.	PUNCT
dti-1424	56	1	int	int	NOUN
dti-1424	56	2	j	j	PROPN
dti-1424	56	3	cardiol	cardiol	NOUN
dti-1424	56	4	.	.	PUNCT
dti-1424	57	1	2015;190:50–52	2015;190:50–52	NUM
dti-1424	57	2	.	.	NOUN
dti-1424	57	3	4	4	NUM
dti-1424	57	4	.	.	X
dti-1424	58	1	rapetto	rapetto	PROPN
dti-1424	58	2	f	f	PROPN
dti-1424	58	3	,	,	PUNCT
dti-1424	58	4	bruno	bruno	PROPN
dti-1424	58	5	vd	vd	PROPN
dti-1424	58	6	,	,	PUNCT
dti-1424	58	7	guida	guida	PROPN
dti-1424	58	8	g	g	PROPN
dti-1424	58	9	,	,	PUNCT
dti-1424	58	10	marsico	marsico	NOUN
dti-1424	58	11	r	r	NOUN
dti-1424	58	12	,	,	PUNCT
dti-1424	58	13	chivasso	chivasso	NOUN
dti-1424	58	14	p	p	X
dti-1424	58	15	,	,	PUNCT
dti-1424	58	16	zebele	zebele	PROPN
dti-1424	58	17	c.	c.	PROPN
dti-1424	58	18	gentamicin	gentamicin	PROPN
dti-1424	58	19	impregnated	impregnate	VERB
dti-1424	58	20	collagen	collagen	NOUN
dti-1424	58	21	sponge	sponge	NOUN
dti-1424	58	22	:	:	PUNCT
dti-1424	58	23	effectiveness	effectiveness	NOUN
dti-1424	58	24	in	in	ADP
dti-1424	58	25	preventing	prevent	VERB
dti-1424	58	26	sternal	sternal	ADJ
dti-1424	58	27	wound	wound	NOUN
dti-1424	58	28	infection	infection	NOUN
dti-1424	58	29	in	in	ADP
dti-1424	58	30	high	high	ADJ
dti-1424	58	31	-	-	PUNCT
dti-1424	58	32	risk	risk	NOUN
dti-1424	58	33	cardiac	cardiac	ADJ
dti-1424	58	34	surgery	surgery	NOUN
dti-1424	58	35	.	.	PUNCT
dti-1424	59	1	drug	drug	NOUN
dti-1424	59	2	target	target	NOUN
dti-1424	59	3	insights	insight	NOUN
dti-1424	59	4	.	.	PUNCT
dti-1424	60	1	2016;10(suppl	2016;10(suppl	NOUN
dti-1424	60	2	1	1	NUM
dti-1424	60	3	):	):	PUNCT
dti-1424	60	4	9–13	9–13	NOUN
dti-1424	60	5	.	.	PUNCT
dti-1424	61	1	figure	figure	NOUN
dti-1424	61	2	1	1	NUM
dti-1424	61	3	.	.	PUNCT
dti-1424	61	4	comparison	comparison	NOUN
dti-1424	61	5	of	of	ADP
dti-1424	61	6	proteomic	proteomic	ADJ
dti-1424	61	7	profile	profile	NOUN
dti-1424	61	8	of	of	ADP
dti-1424	61	9	secreted	secrete	VERB
dti-1424	61	10	proteins	protein	NOUN
dti-1424	61	11	by	by	ADP
dti-1424	61	12	saphenous	saphenous	ADJ
dti-1424	61	13	vein	vein	ADJ
dti-1424	61	14	graft	graft	NOUN
dti-1424	61	15	,	,	PUNCT
dti-1424	61	16	internal	internal	ADJ
dti-1424	61	17	thoracic	thoracic	NOUN
dti-1424	61	18	artery	artery	NOUN
dti-1424	61	19	(	(	PUNCT
dti-1424	61	20	ita	ita	NOUN
dti-1424	61	21	)	)	PUNCT
dti-1424	61	22	and	and	CCONJ
dti-1424	61	23	aorta	aorta	PROPN
dti-1424	61	24	.	.	PUNCT
dti-1424	62	1	http://www.la-press.com/drug-target-insights-journal-j23	http://www.la-press.com/drug-target-insights-journal-j23	AUX
dti-1424	62	2	http://www.la-press.com	http://www.la-press.com	X
dti-1424	62	3	spadaccio	spadaccio	PROPN
dti-1424	62	4	et	et	PROPN
dti-1424	62	5	al	al	PROPN
dti-1424	62	6	drug	drug	PROPN
dti-1424	62	7	target	target	NOUN
dti-1424	62	8	insights	insight	NOUN
dti-1424	62	9	2016:10(s1)18	2016:10(s1)18	NOUN
dti-1424	62	10	5	5	NUM
dti-1424	62	11	.	.	PUNCT
dti-1424	62	12	spadaccio	spadaccio	PROPN
dti-1424	62	13	c	c	PROPN
dti-1424	62	14	,	,	PUNCT
dti-1424	62	15	nappi	nappi	PROPN
dti-1424	62	16	f	f	PROPN
dti-1424	62	17	,	,	PUNCT
dti-1424	62	18	de	de	PROPN
dti-1424	62	19	marco	marco	PROPN
dti-1424	62	20	f	f	PROPN
dti-1424	62	21	,	,	PUNCT
dti-1424	62	22	et	et	PROPN
dti-1424	62	23	al	al	PROPN
dti-1424	62	24	.	.	PROPN
dti-1424	62	25	preliminary	preliminary	ADJ
dti-1424	62	26	in	in	ADP
dti-1424	62	27	vivo	vivo	ADJ
dti-1424	62	28	evaluation	evaluation	NOUN
dti-1424	62	29	of	of	ADP
dti-1424	62	30	a	a	DET
dti-1424	62	31	hybrid	hybrid	ADJ
dti-1424	62	32	armored	armored	ADJ
dti-1424	62	33	vascular	vascular	ADJ
dti-1424	62	34	graft	graft	NOUN
dti-1424	62	35	combining	combine	VERB
dti-1424	62	36	electrospinning	electrospinne	VERB
dti-1424	62	37	and	and	CCONJ
dti-1424	62	38	additive	additive	ADJ
dti-1424	62	39	manufacturing	manufacturing	NOUN
dti-1424	62	40	techniques	technique	NOUN
dti-1424	62	41	.	.	PUNCT
dti-1424	63	1	drug	drug	NOUN
dti-1424	63	2	target	target	NOUN
dti-1424	63	3	insights	insight	NOUN
dti-1424	63	4	.	.	PUNCT
dti-1424	64	1	2016;10(suppl	2016;10(suppl	PROPN
dti-1424	64	2	1):1–7	1):1–7	X
dti-1424	64	3	.	.	PUNCT
dti-1424	65	1	6	6	NUM
dti-1424	65	2	.	.	X
dti-1424	65	3	spadaccio	spadaccio	PROPN
dti-1424	65	4	c	c	X
dti-1424	65	5	,	,	PUNCT
dti-1424	65	6	chello	chello	PROPN
dti-1424	65	7	m	m	PROPN
dti-1424	65	8	,	,	PUNCT
dti-1424	65	9	trombetta	trombetta	PROPN
dti-1424	65	10	m	m	PROPN
dti-1424	65	11	,	,	PUNCT
dti-1424	65	12	rainer	rainer	VERB
dti-1424	65	13	a	a	PRON
dti-1424	65	14	,	,	PUNCT
dti-1424	65	15	toyoda	toyoda	PROPN
dti-1424	65	16	y	y	PROPN
dti-1424	65	17	,	,	PUNCT
dti-1424	65	18	genovese	genovese	PROPN
dti-1424	65	19	ja	ja	PROPN
dti-1424	65	20	.	.	PROPN
dti-1424	65	21	drug	drug	PROPN
dti-1424	65	22	releasing	release	VERB
dti-1424	65	23	systems	system	NOUN
dti-1424	65	24	in	in	ADP
dti-1424	65	25	cardiovascular	cardiovascular	ADJ
dti-1424	65	26	tissue	tissue	NOUN
dti-1424	65	27	engineering	engineering	NOUN
dti-1424	65	28	.	.	PUNCT
dti-1424	66	1	j	j	PROPN
dti-1424	66	2	cell	cell	PROPN
dti-1424	66	3	mol	mol	ADP
dti-1424	66	4	med	med	PROPN
dti-1424	66	5	.	.	PUNCT
dti-1424	67	1	2009;13(3):422–439	2009;13(3):422–439	NUM
dti-1424	67	2	.	.	PUNCT
dti-1424	67	3	7	7	NUM
dti-1424	67	4	.	.	X
dti-1424	67	5	rainer	rainer	PROPN
dti-1424	67	6	a	a	DET
dti-1424	67	7	,	,	PUNCT
dti-1424	67	8	spadaccio	spadaccio	NOUN
dti-1424	67	9	c	c	NOUN
dti-1424	67	10	,	,	PUNCT
dti-1424	67	11	sedati	sedati	PROPN
dti-1424	67	12	p	p	PROPN
dti-1424	67	13	,	,	PUNCT
dti-1424	68	1	et	et	PROPN
dti-1424	68	2	al	al	PROPN
dti-1424	68	3	.	.	PROPN
dti-1424	68	4	electrospun	electrospun	PROPN
dti-1424	68	5	hydroxyapatite	hydroxyapatite	NOUN
dti-1424	68	6	-	-	PUNCT
dti-1424	68	7	functionalized	functionalize	VERB
dti-1424	68	8	plla	plla	NOUN
dti-1424	68	9	scaffold	scaffold	NOUN
dti-1424	68	10	:	:	PUNCT
dti-1424	68	11	potential	potential	ADJ
dti-1424	68	12	applications	application	NOUN
dti-1424	68	13	in	in	ADP
dti-1424	68	14	sternal	sternal	ADJ
dti-1424	68	15	bone	bone	NOUN
dti-1424	68	16	healing	healing	NOUN
dti-1424	68	17	.	.	PUNCT
dti-1424	69	1	ann	ann	PROPN
dti-1424	69	2	biomed	biome	VERB
dti-1424	69	3	eng	eng	PROPN
dti-1424	69	4	.	.	PUNCT
dti-1424	69	5	2011;39(7):1882–1890	2011;39(7):1882–1890	NUM
dti-1424	69	6	.	.	PUNCT
dti-1424	70	1	8	8	NUM
dti-1424	70	2	.	.	NOUN
dti-1424	70	3	spadaccio	spadaccio	PROPN
dti-1424	70	4	c	c	NOUN
dti-1424	70	5	,	,	PUNCT
dti-1424	70	6	rainer	rainer	NOUN
dti-1424	70	7	a	a	PRON
dti-1424	70	8	,	,	PUNCT
dti-1424	70	9	centola	centola	PROPN
dti-1424	70	10	m	m	PROPN
dti-1424	70	11	,	,	PUNCT
dti-1424	70	12	et	et	PROPN
dti-1424	70	13	al	al	PROPN
dti-1424	70	14	.	.	PROPN
dti-1424	70	15	heparin	heparin	NOUN
dti-1424	70	16	-	-	PUNCT
dti-1424	70	17	releasing	release	VERB
dti-1424	70	18	scaffold	scaffold	NOUN
dti-1424	70	19	for	for	ADP
dti-1424	70	20	stem	stem	NOUN
dti-1424	70	21	cells	cell	NOUN
dti-1424	70	22	:	:	PUNCT
dti-1424	70	23	a	a	DET
dti-1424	70	24	differentiating	differentiate	VERB
dti-1424	70	25	device	device	NOUN
dti-1424	70	26	for	for	ADP
dti-1424	70	27	vascular	vascular	ADJ
dti-1424	70	28	aims	aim	NOUN
dti-1424	70	29	.	.	PUNCT
dti-1424	71	1	regen	regen	PROPN
dti-1424	71	2	med	med	PROPN
dti-1424	71	3	.	.	PUNCT
dti-1424	72	1	2010;5(4):645–657	2010;5(4):645–657	NUM
dti-1424	72	2	.	.	NOUN
dti-1424	73	1	9	9	NUM
dti-1424	73	2	.	.	PUNCT
dti-1424	73	3	gaudino	gaudino	PROPN
dti-1424	73	4	m	m	PROPN
dti-1424	73	5	,	,	PUNCT
dti-1424	73	6	cellini	cellini	PROPN
dti-1424	73	7	c	c	PROPN
dti-1424	73	8	,	,	PUNCT
dti-1424	73	9	pragliola	pragliola	PROPN
dti-1424	73	10	c	c	AUX
dti-1424	73	11	,	,	PUNCT
dti-1424	73	12	et	et	PROPN
dti-1424	73	13	al	al	PROPN
dti-1424	73	14	.	.	PROPN
dti-1424	74	1	arterial	arterial	NOUN
dti-1424	74	2	versus	versus	ADP
dti-1424	74	3	venous	venous	ADJ
dti-1424	74	4	bypass	bypass	NOUN
dti-1424	74	5	grafts	graft	NOUN
dti-1424	74	6	in	in	ADP
dti-1424	74	7	patients	patient	NOUN
dti-1424	74	8	with	with	ADP
dti-1424	74	9	in	in	ADP
dti-1424	74	10	-	-	PUNCT
dti-1424	74	11	stent	stent	NOUN
dti-1424	74	12	restenosis	restenosis	NOUN
dti-1424	74	13	.	.	PUNCT
dti-1424	74	14	circulation	circulation	NOUN
dti-1424	74	15	.	.	PUNCT
dti-1424	75	1	2005;112(9	2005;112(9	NUM
dti-1424	75	2	suppl):i265–269	suppl):i265–269	PRON
dti-1424	75	3	.	.	PUNCT
dti-1424	76	1	10	10	NUM
dti-1424	76	2	.	.	PUNCT
dti-1424	77	1	hannan	hannan	PROPN
dti-1424	77	2	el	el	PROPN
dti-1424	77	3	,	,	PUNCT
dti-1424	77	4	racz	racz	NOUN
dti-1424	77	5	mj	mj	PROPN
dti-1424	77	6	,	,	PUNCT
dti-1424	77	7	walford	walford	NOUN
dti-1424	77	8	g	g	NOUN
dti-1424	77	9	,	,	PUNCT
dti-1424	77	10	et	et	PROPN
dti-1424	77	11	al	al	PROPN
dti-1424	77	12	.	.	PUNCT
dti-1424	78	1	long	long	ADJ
dti-1424	78	2	-	-	PUNCT
dti-1424	78	3	term	term	NOUN
dti-1424	78	4	outcomes	outcome	NOUN
dti-1424	78	5	of	of	ADP
dti-1424	78	6	coronary	coronary	ADJ
dti-1424	78	7	-	-	PUNCT
dti-1424	78	8	artery	artery	NOUN
dti-1424	78	9	bypass	bypass	NOUN
dti-1424	78	10	grafting	grafting	NOUN
dti-1424	78	11	versus	versus	ADP
dti-1424	78	12	stent	stent	NOUN
dti-1424	78	13	implantation	implantation	NOUN
dti-1424	78	14	.	.	PUNCT
dti-1424	79	1	n	n	CCONJ
dti-1424	79	2	engl	engl	PROPN
dti-1424	79	3	j	j	PROPN
dti-1424	79	4	med	med	PROPN
dti-1424	79	5	.	.	PUNCT
dti-1424	80	1	2005;352(21):2174–2183	2005;352(21):2174–2183	NUM
dti-1424	80	2	.	.	X
dti-1424	81	1	11	11	NUM
dti-1424	81	2	.	.	PUNCT
dti-1424	82	1	al	al	PROPN
dti-1424	82	2	-	-	PUNCT
dti-1424	82	3	attar	attar	PROPN
dti-1424	82	4	n	n	PROPN
dti-1424	82	5	,	,	PUNCT
dti-1424	82	6	nataf	nataf	NOUN
dti-1424	82	7	p.	p.	NOUN
dti-1424	82	8	multiple	multiple	ADJ
dti-1424	82	9	extensive	extensive	ADJ
dti-1424	82	10	coronary	coronary	ADJ
dti-1424	82	11	artery	artery	NOUN
dti-1424	82	12	stenting	stenting	NOUN
dti-1424	82	13	:	:	PUNCT
dti-1424	82	14	does	do	AUX
dti-1424	82	15	it	it	PRON
dti-1424	82	16	compromise	compromise	VERB
dti-1424	82	17	future	future	ADJ
dti-1424	82	18	surgical	surgical	ADJ
dti-1424	82	19	revascularization	revascularization	NOUN
dti-1424	82	20	?	?	PUNCT
dti-1424	83	1	curr	curr	PROPN
dti-1424	83	2	opin	opin	NOUN
dti-1424	83	3	cardiol	cardiol	NOUN
dti-1424	83	4	.	.	PUNCT
dti-1424	84	1	2007;22(6):529–533	2007;22(6):529–533	NUM
dti-1424	84	2	.	.	PROPN
dti-1424	84	3	12	12	NUM
dti-1424	84	4	.	.	PUNCT
dti-1424	85	1	harrison	harrison	PROPN
dti-1424	85	2	dg	dg	PROPN
dti-1424	85	3	.	.	PUNCT
dti-1424	86	1	endothelial	endothelial	ADJ
dti-1424	86	2	dysfunction	dysfunction	NOUN
dti-1424	86	3	in	in	ADP
dti-1424	86	4	the	the	DET
dti-1424	86	5	coronary	coronary	ADJ
dti-1424	86	6	microcirculation	microcirculation	NOUN
dti-1424	86	7	:	:	PUNCT
dti-1424	86	8	a	a	DET
dti-1424	86	9	new	new	ADJ
dti-1424	86	10	clinical	clinical	ADJ
dti-1424	86	11	entity	entity	NOUN
dti-1424	86	12	or	or	CCONJ
dti-1424	86	13	an	an	DET
dti-1424	86	14	experimental	experimental	ADJ
dti-1424	86	15	finding	finding	NOUN
dti-1424	86	16	?	?	PUNCT
dti-1424	87	1	j	j	PROPN
dti-1424	87	2	clin	clin	PROPN
dti-1424	87	3	invest	invest	PROPN
dti-1424	87	4	.	.	PUNCT
dti-1424	88	1	1993;91(1):1–2	1993;91(1):1–2	X
dti-1424	88	2	.	.	PUNCT
dti-1424	89	1	13	13	NUM
dti-1424	89	2	.	.	PUNCT
dti-1424	89	3	west	west	PROPN
dti-1424	89	4	ne	ne	PROPN
dti-1424	89	5	,	,	PUNCT
dti-1424	89	6	qian	qian	PROPN
dti-1424	89	7	h	h	NOUN
dti-1424	89	8	,	,	PUNCT
dti-1424	89	9	guzik	guzik	NOUN
dti-1424	89	10	tj	tj	NOUN
dti-1424	89	11	,	,	PUNCT
dti-1424	89	12	et	et	PROPN
dti-1424	89	13	al	al	PROPN
dti-1424	89	14	.	.	PROPN
dti-1424	89	15	nitric	nitric	ADJ
dti-1424	89	16	oxide	oxide	NOUN
dti-1424	89	17	synthase	synthase	NOUN
dti-1424	89	18	(	(	PUNCT
dti-1424	89	19	nnos	nno	NOUN
dti-1424	89	20	)	)	PUNCT
dti-1424	89	21	gene	gene	NOUN
dti-1424	89	22	transfer	transfer	NOUN
dti-1424	89	23	modifies	modify	VERB
dti-1424	89	24	venous	venous	ADJ
dti-1424	89	25	bypass	bypass	NOUN
dti-1424	89	26	graft	graft	NOUN
dti-1424	89	27	remodeling	remodeling	NOUN
dti-1424	89	28	:	:	PUNCT
dti-1424	89	29	effects	effect	NOUN
dti-1424	89	30	on	on	ADP
dti-1424	89	31	vascular	vascular	ADJ
dti-1424	89	32	smooth	smooth	ADJ
dti-1424	89	33	muscle	muscle	NOUN
dti-1424	89	34	cell	cell	NOUN
dti-1424	89	35	differentiation	differentiation	NOUN
dti-1424	89	36	and	and	CCONJ
dti-1424	89	37	superoxide	superoxide	NOUN
dti-1424	89	38	production	production	NOUN
dti-1424	89	39	.	.	PUNCT
dti-1424	90	1	circulation	circulation	NOUN
dti-1424	90	2	.	.	PUNCT
dti-1424	91	1	2001;104(13):1526–1532	2001;104(13):1526–1532	NUM
dti-1424	91	2	.	.	NOUN
dti-1424	91	3	14	14	NUM
dti-1424	91	4	.	.	PUNCT
dti-1424	92	1	yang	yang	PROPN
dti-1424	92	2	z	z	PROPN
dti-1424	92	3	,	,	PUNCT
dti-1424	92	4	ruschitzka	ruschitzka	PROPN
dti-1424	92	5	f	f	PROPN
dti-1424	92	6	,	,	PUNCT
dti-1424	92	7	rabelink	rabelink	PROPN
dti-1424	92	8	tj	tj	PROPN
dti-1424	92	9	,	,	PUNCT
dti-1424	92	10	et	et	PROPN
dti-1424	92	11	al	al	PROPN
dti-1424	92	12	.	.	PUNCT
dti-1424	93	1	different	different	ADJ
dti-1424	93	2	effects	effect	NOUN
dti-1424	93	3	of	of	ADP
dti-1424	93	4	thrombin	thrombin	NOUN
dti-1424	93	5	receptor	receptor	NOUN
dti-1424	93	6	activation	activation	NOUN
dti-1424	93	7	on	on	ADP
dti-1424	93	8	endothelium	endothelium	NOUN
dti-1424	93	9	and	and	CCONJ
dti-1424	93	10	smooth	smooth	ADJ
dti-1424	93	11	muscle	muscle	NOUN
dti-1424	93	12	cells	cell	NOUN
dti-1424	93	13	of	of	ADP
dti-1424	93	14	human	human	ADJ
dti-1424	93	15	coronary	coronary	ADJ
dti-1424	93	16	bypass	bypass	NOUN
dti-1424	93	17	vessels	vessel	NOUN
dti-1424	93	18	.	.	PUNCT
dti-1424	94	1	implications	implication	NOUN
dti-1424	94	2	for	for	ADP
dti-1424	94	3	venous	venous	ADJ
dti-1424	94	4	bypass	bypass	NOUN
dti-1424	94	5	graft	graft	NOUN
dti-1424	94	6	failure	failure	NOUN
dti-1424	94	7	.	.	PUNCT
dti-1424	95	1	circulation	circulation	NOUN
dti-1424	95	2	.	.	PUNCT
dti-1424	96	1	1997;95(7	1997;95(7	NUM
dti-1424	96	2	):	):	PUNCT
dti-1424	96	3	1870–1876	1870–1876	NUM
dti-1424	96	4	.	.	PUNCT
dti-1424	97	1	15	15	NUM
dti-1424	97	2	.	.	X
dti-1424	97	3	takamori	takamori	NOUN
dti-1424	97	4	n	n	PROPN
dti-1424	97	5	,	,	PUNCT
dti-1424	97	6	azuma	azuma	NOUN
dti-1424	97	7	h	h	NOUN
dti-1424	97	8	,	,	PUNCT
dti-1424	97	9	kato	kato	PROPN
dti-1424	97	10	m	m	PROPN
dti-1424	97	11	,	,	PUNCT
dti-1424	97	12	et	et	PROPN
dti-1424	97	13	al	al	PROPN
dti-1424	97	14	.	.	PROPN
dti-1424	97	15	high	high	ADJ
dti-1424	97	16	plasma	plasma	NOUN
dti-1424	97	17	heparin	heparin	ADJ
dti-1424	97	18	cofactor	cofactor	NOUN
dti-1424	97	19	ii	ii	NOUN
dti-1424	97	20	activity	activity	NOUN
dti-1424	97	21	is	be	AUX
dti-1424	97	22	associated	associate	VERB
dti-1424	97	23	with	with	ADP
dti-1424	97	24	reduced	reduced	ADJ
dti-1424	97	25	incidence	incidence	NOUN
dti-1424	97	26	of	of	ADP
dti-1424	97	27	in	in	ADP
dti-1424	97	28	-	-	PUNCT
dti-1424	97	29	stent	stent	NOUN
dti-1424	97	30	restenosis	restenosis	NOUN
dti-1424	97	31	after	after	ADP
dti-1424	97	32	percutaneous	percutaneous	ADJ
dti-1424	97	33	coronary	coronary	ADJ
dti-1424	97	34	intervention	intervention	NOUN
dti-1424	97	35	.	.	PUNCT
dti-1424	98	1	circulation	circulation	NOUN
dti-1424	98	2	.	.	PUNCT
dti-1424	99	1	2004;109(4):481–486	2004;109(4):481–486	NUM
dti-1424	99	2	.	.	PROPN
dti-1424	99	3	16	16	NUM
dti-1424	99	4	.	.	PUNCT
dti-1424	100	1	tarr	tarr	PROPN
dti-1424	100	2	fi	fi	PROPN
dti-1424	100	3	,	,	PUNCT
dti-1424	100	4	sasvari	sasvari	PROPN
dti-1424	100	5	m	m	NOUN
dti-1424	100	6	,	,	PUNCT
dti-1424	100	7	tarr	tarr	PROPN
dti-1424	100	8	m	m	PROPN
dti-1424	100	9	,	,	PUNCT
dti-1424	100	10	racz	racz	VERB
dti-1424	100	11	r.	r.	NOUN
dti-1424	100	12	evidence	evidence	NOUN
dti-1424	100	13	of	of	ADP
dti-1424	100	14	nitric	nitric	ADJ
dti-1424	100	15	oxide	oxide	NOUN
dti-1424	100	16	produced	produce	VERB
dti-1424	100	17	by	by	ADP
dti-1424	100	18	the	the	DET
dti-1424	100	19	internal	internal	ADJ
dti-1424	100	20	mammary	mammary	ADJ
dti-1424	100	21	artery	artery	NOUN
dti-1424	100	22	graft	graft	NOUN
dti-1424	100	23	in	in	ADP
dti-1424	100	24	venous	venous	ADJ
dti-1424	100	25	drainage	drainage	NOUN
dti-1424	100	26	of	of	ADP
dti-1424	100	27	the	the	DET
dti-1424	100	28	recipient	recipient	NOUN
dti-1424	100	29	coronary	coronary	ADJ
dti-1424	100	30	artery	artery	NOUN
dti-1424	100	31	.	.	PUNCT
dti-1424	101	1	ann	ann	PROPN
dti-1424	101	2	thorac	thorac	PROPN
dti-1424	101	3	surg	surg	NOUN
dti-1424	101	4	.	.	PUNCT
dti-1424	102	1	2005;80(5):1728–1731	2005;80(5):1728–1731	NOUN
dti-1424	102	2	.	.	PUNCT
dti-1424	103	1	17	17	NUM
dti-1424	103	2	.	.	PUNCT
dti-1424	104	1	luscher	luscher	PROPN
dti-1424	104	2	tf	tf	PROPN
dti-1424	104	3	,	,	PUNCT
dti-1424	104	4	diederich	diederich	NOUN
dti-1424	104	5	d	d	PROPN
dti-1424	104	6	,	,	PUNCT
dti-1424	104	7	siebenmann	siebenmann	PROPN
dti-1424	104	8	r	r	PROPN
dti-1424	104	9	,	,	PUNCT
dti-1424	104	10	et	et	PROPN
dti-1424	104	11	al	al	PROPN
dti-1424	104	12	.	.	PROPN
dti-1424	104	13	difference	difference	NOUN
dti-1424	104	14	between	between	ADP
dti-1424	104	15	endotheliumdependent	endotheliumdependent	ADJ
dti-1424	104	16	relaxation	relaxation	NOUN
dti-1424	104	17	in	in	ADP
dti-1424	104	18	arterial	arterial	NOUN
dti-1424	104	19	and	and	CCONJ
dti-1424	104	20	in	in	ADP
dti-1424	104	21	venous	venous	ADJ
dti-1424	104	22	coronary	coronary	ADJ
dti-1424	104	23	bypass	bypass	NOUN
dti-1424	104	24	grafts	graft	NOUN
dti-1424	104	25	.	.	PUNCT
dti-1424	105	1	n	n	PRON
dti-1424	105	2	engl	engl	PROPN
dti-1424	105	3	j	j	PROPN
dti-1424	105	4	med	med	PROPN
dti-1424	105	5	.	.	PUNCT
dti-1424	106	1	1988;319(8):462–467	1988;319(8):462–467	NUM
dti-1424	106	2	.	.	PROPN
dti-1424	106	3	18	18	NUM
dti-1424	106	4	.	.	PUNCT
dti-1424	107	1	butterfield	butterfield	PROPN
dti-1424	107	2	da	da	PROPN
dti-1424	107	3	,	,	PUNCT
dti-1424	107	4	gu	gu	NOUN
dti-1424	107	5	l	l	PROPN
dti-1424	107	6	,	,	PUNCT
dti-1424	107	7	di	di	X
dti-1424	107	8	domenico	domenico	PROPN
dti-1424	107	9	f	f	PROPN
dti-1424	107	10	,	,	PUNCT
dti-1424	107	11	robinson	robinson	PROPN
dti-1424	107	12	ra	ra	PROPN
dti-1424	107	13	.	.	PROPN
dti-1424	107	14	mass	mass	PROPN
dti-1424	107	15	spectrometry	spectrometry	NOUN
dti-1424	107	16	and	and	CCONJ
dti-1424	107	17	redox	redox	ADJ
dti-1424	107	18	proteomics	proteomic	NOUN
dti-1424	107	19	:	:	PUNCT
dti-1424	107	20	applications	application	NOUN
dti-1424	107	21	in	in	ADP
dti-1424	107	22	disease	disease	NOUN
dti-1424	107	23	.	.	PUNCT
dti-1424	108	1	mass	mass	PROPN
dti-1424	108	2	spectrom	spectrom	PROPN
dti-1424	108	3	rev	rev	VERB
dti-1424	108	4	.	.	PUNCT
dti-1424	109	1	2014;33(4):277–301	2014;33(4):277–301	NUM
dti-1424	109	2	.	.	NOUN
dti-1424	109	3	19	19	NUM
dti-1424	109	4	.	.	NOUN
dti-1424	109	5	spadaccio	spadaccio	PROPN
dti-1424	109	6	c	c	X
dti-1424	109	7	,	,	PUNCT
dti-1424	109	8	di	di	X
dti-1424	109	9	domenico	domenico	PROPN
dti-1424	109	10	f	f	PROPN
dti-1424	109	11	,	,	PUNCT
dti-1424	109	12	perluigi	perluigi	PROPN
dti-1424	109	13	m	m	PROPN
dti-1424	109	14	,	,	PUNCT
dti-1424	109	15	et	et	PROPN
dti-1424	109	16	al	al	PROPN
dti-1424	109	17	.	.	PROPN
dti-1424	110	1	serum	serum	PROPN
dti-1424	110	2	proteomics	proteomic	NOUN
dti-1424	110	3	in	in	ADP
dti-1424	110	4	patients	patient	NOUN
dti-1424	110	5	with	with	ADP
dti-1424	110	6	diagnosis	diagnosis	NOUN
dti-1424	110	7	of	of	ADP
dti-1424	110	8	abdominal	abdominal	ADJ
dti-1424	110	9	aortic	aortic	ADJ
dti-1424	110	10	aneurysm	aneurysm	NOUN
dti-1424	110	11	.	.	PUNCT
dti-1424	111	1	cardiovasc	cardiovasc	PROPN
dti-1424	111	2	pathol	pathol	PROPN
dti-1424	111	3	.	.	PUNCT
dti-1424	112	1	2012;21(4):283–290	2012;21(4):283–290	NUM
dti-1424	112	2	.	.	PUNCT
dti-1424	112	3	20	20	NUM
dti-1424	112	4	.	.	PUNCT
dti-1424	113	1	lyck	lyck	PROPN
dti-1424	113	2	hansen	hansen	PROPN
dti-1424	113	3	m	m	PROPN
dti-1424	113	4	,	,	PUNCT
dti-1424	113	5	beck	beck	PROPN
dti-1424	113	6	hc	hc	PROPN
dti-1424	113	7	,	,	PUNCT
dti-1424	113	8	irmukhamedov	irmukhamedov	PROPN
dti-1424	113	9	a	a	PROPN
dti-1424	113	10	,	,	PUNCT
dti-1424	113	11	jensen	jensen	PROPN
dti-1424	113	12	ps	ps	PROPN
dti-1424	113	13	,	,	PUNCT
dti-1424	113	14	olsen	olsen	PROPN
dti-1424	113	15	mh	mh	PROPN
dti-1424	113	16	,	,	PUNCT
dti-1424	113	17	rasmussen	rasmussen	PROPN
dti-1424	113	18	lm	lm	PROPN
dti-1424	113	19	.	.	PUNCT
dti-1424	114	1	proteome	proteome	PROPN
dti-1424	114	2	analysis	analysis	NOUN
dti-1424	114	3	of	of	ADP
dti-1424	114	4	human	human	ADJ
dti-1424	114	5	arterial	arterial	ADJ
dti-1424	114	6	tissue	tissue	NOUN
dti-1424	114	7	discloses	disclose	VERB
dti-1424	114	8	associations	association	NOUN
dti-1424	114	9	between	between	ADP
dti-1424	114	10	the	the	DET
dti-1424	114	11	vascular	vascular	ADJ
dti-1424	114	12	content	content	NOUN
dti-1424	114	13	of	of	ADP
dti-1424	114	14	small	small	ADJ
dti-1424	114	15	leucine	leucine	NOUN
dti-1424	114	16	-	-	PUNCT
dti-1424	114	17	rich	rich	ADJ
dti-1424	114	18	repeat	repeat	NOUN
dti-1424	114	19	proteoglycans	proteoglycan	NOUN
dti-1424	114	20	and	and	CCONJ
dti-1424	114	21	pulse	pulse	NOUN
dti-1424	114	22	wave	wave	NOUN
dti-1424	114	23	velocity	velocity	NOUN
dti-1424	114	24	.	.	PUNCT
dti-1424	115	1	arterioscler	arterioscler	PROPN
dti-1424	115	2	thromb	thromb	PROPN
dti-1424	115	3	vasc	vasc	PROPN
dti-1424	115	4	biol	biol	PROPN
dti-1424	115	5	.	.	PUNCT
dti-1424	116	1	2015;35(8):1896–1903	2015;35(8):1896–1903	NOUN
dti-1424	116	2	.	.	PUNCT
dti-1424	117	1	21	21	NUM
dti-1424	117	2	.	.	X
dti-1424	117	3	de	de	X
dti-1424	117	4	la	la	X
dti-1424	117	5	cuesta	cuesta	X
dti-1424	118	1	f	f	X
dti-1424	118	2	,	,	PUNCT
dti-1424	118	3	zubiri	zubiri	PROPN
dti-1424	118	4	i	i	PRON
dti-1424	118	5	,	,	PUNCT
dti-1424	118	6	maroto	maroto	PROPN
dti-1424	118	7	as	as	ADP
dti-1424	118	8	,	,	PUNCT
dti-1424	118	9	et	et	PROPN
dti-1424	118	10	al	al	PROPN
dti-1424	118	11	.	.	PUNCT
dti-1424	119	1	deregulation	deregulation	NOUN
dti-1424	119	2	of	of	ADP
dti-1424	119	3	smooth	smooth	ADJ
dti-1424	119	4	muscle	muscle	NOUN
dti-1424	119	5	cell	cell	NOUN
dti-1424	119	6	cytoskeleton	cytoskeleton	NOUN
dti-1424	119	7	within	within	ADP
dti-1424	119	8	the	the	DET
dti-1424	119	9	human	human	ADJ
dti-1424	119	10	atherosclerotic	atherosclerotic	ADJ
dti-1424	119	11	coronary	coronary	ADJ
dti-1424	119	12	media	medium	NOUN
dti-1424	119	13	layer	layer	NOUN
dti-1424	119	14	.	.	PUNCT
dti-1424	120	1	j	j	NOUN
dti-1424	120	2	proteomics	proteomic	NOUN
dti-1424	120	3	.	.	PUNCT
dti-1424	121	1	2013;82:155–165	2013;82:155–165	NUM
dti-1424	121	2	.	.	PUNCT
dti-1424	122	1	22	22	NUM
dti-1424	122	2	.	.	PUNCT
dti-1424	122	3	de	de	X
dti-1424	122	4	la	la	X
dti-1424	122	5	cuesta	cuesta	X
dti-1424	123	1	f	f	X
dti-1424	123	2	,	,	PUNCT
dti-1424	123	3	alvarez	alvarez	PROPN
dti-1424	123	4	-	-	PUNCT
dti-1424	123	5	llamas	llamas	PROPN
dti-1424	123	6	g	g	NOUN
dti-1424	123	7	,	,	PUNCT
dti-1424	123	8	maroto	maroto	PROPN
dti-1424	123	9	as	as	ADP
dti-1424	123	10	,	,	PUNCT
dti-1424	123	11	et	et	PROPN
dti-1424	123	12	al	al	PROPN
dti-1424	123	13	.	.	PUNCT
dti-1424	124	1	a	a	DET
dti-1424	124	2	proteomic	proteomic	ADJ
dti-1424	124	3	focus	focus	NOUN
dti-1424	124	4	on	on	ADP
dti-1424	124	5	the	the	DET
dti-1424	124	6	alterations	alteration	NOUN
dti-1424	124	7	occurring	occur	VERB
dti-1424	124	8	at	at	ADP
dti-1424	124	9	the	the	DET
dti-1424	124	10	human	human	ADJ
dti-1424	124	11	atherosclerotic	atherosclerotic	ADJ
dti-1424	124	12	coronary	coronary	ADJ
dti-1424	124	13	intima	intima	NOUN
dti-1424	124	14	.	.	PUNCT
dti-1424	125	1	mol	mol	ADP
dti-1424	125	2	cell	cell	NOUN
dti-1424	125	3	proteomics	proteomic	NOUN
dti-1424	125	4	.	.	PUNCT
dti-1424	126	1	2011;10(4):m110003517	2011;10(4):m110003517	X
dti-1424	126	2	.	.	NOUN
dti-1424	127	1	23	23	NUM
dti-1424	127	2	.	.	X
dti-1424	127	3	de	de	X
dti-1424	127	4	la	la	X
dti-1424	127	5	cuesta	cuesta	X
dti-1424	128	1	f	f	X
dti-1424	128	2	,	,	PUNCT
dti-1424	128	3	barderas	barderas	X
dti-1424	128	4	mg	mg	PROPN
dti-1424	128	5	,	,	PUNCT
dti-1424	128	6	calvo	calvo	PROPN
dti-1424	128	7	e	e	PROPN
dti-1424	128	8	,	,	PUNCT
dti-1424	128	9	et	et	PROPN
dti-1424	128	10	al	al	PROPN
dti-1424	128	11	.	.	PROPN
dti-1424	129	1	secretome	secretome	PROPN
dti-1424	129	2	analysis	analysis	NOUN
dti-1424	129	3	of	of	ADP
dti-1424	129	4	atherosclerotic	atherosclerotic	ADJ
dti-1424	129	5	and	and	CCONJ
dti-1424	129	6	non	non	ADJ
dti-1424	129	7	-	-	ADJ
dti-1424	129	8	atherosclerotic	atherosclerotic	ADJ
dti-1424	129	9	arteries	artery	NOUN
dti-1424	129	10	reveals	reveal	VERB
dti-1424	129	11	dynamic	dynamic	ADJ
dti-1424	129	12	extracellular	extracellular	ADJ
dti-1424	129	13	remodeling	remodeling	NOUN
dti-1424	129	14	during	during	ADP
dti-1424	129	15	pathogenesis	pathogenesis	NOUN
dti-1424	129	16	.	.	PUNCT
dti-1424	130	1	j	j	PROPN
dti-1424	130	2	proteomics	proteomic	NOUN
dti-1424	130	3	.	.	PUNCT
dti-1424	131	1	2012;75(10):2960–2971	2012;75(10):2960–2971	NUM
dti-1424	131	2	.	.	PUNCT
dti-1424	132	1	clinical	clinical	ADJ
dti-1424	132	2	lecturer	lecturer	NOUN
dti-1424	132	3	at	at	ADP
dti-1424	132	4	the	the	DET
dti-1424	132	5	institute	institute	NOUN
dti-1424	132	6	of	of	ADP
dti-1424	132	7	cardiovascular	cardiovascular	ADJ
dti-1424	132	8	and	and	CCONJ
dti-1424	132	9	medical	medical	ADJ
dti-1424	132	10	science	science	NOUN
dti-1424	132	11	of	of	ADP
dti-1424	132	12	the	the	DET
dti-1424	132	13	university	university	NOUN
dti-1424	132	14	of	of	ADP
dti-1424	132	15	glasgow	glasgow	PROPN
dti-1424	132	16	and	and	CCONJ
dti-1424	132	17	holds	hold	VERB
dti-1424	132	18	a	a	DET
dti-1424	132	19	clinical	clinical	ADJ
dti-1424	132	20	position	position	NOUN
dti-1424	132	21	of	of	ADP
dti-1424	132	22	cardiothoracic	cardiothoracic	NOUN
dti-1424	132	23	surgical	surgical	ADJ
dti-1424	132	24	fellow	fellow	NOUN
dti-1424	132	25	at	at	ADP
dti-1424	132	26	the	the	DET
dti-1424	132	27	cardiothoracic	cardiothoracic	NOUN
dti-1424	132	28	surgery	surgery	NOUN
dti-1424	132	29	department	department	NOUN
dti-1424	132	30	of	of	ADP
dti-1424	132	31	the	the	DET
dti-1424	132	32	golden	golden	PROPN
dti-1424	132	33	jubilee	jubilee	PROPN
dti-1424	132	34	national	national	PROPN
dti-1424	132	35	hospital	hospital	PROPN
dti-1424	132	36	.	.	PUNCT
dti-1424	133	1	he	he	PRON
dti-1424	133	2	completed	complete	VERB
dti-1424	133	3	his	his	PRON
dti-1424	133	4	phd	phd	NOUN
dti-1424	133	5	at	at	ADP
dti-1424	133	6	university	university	PROPN
dti-1424	133	7	la	la	PROPN
dti-1424	133	8	sapienza	sapienza	PROPN
dti-1424	133	9	of	of	ADP
dti-1424	133	10	rome	rome	PROPN
dti-1424	133	11	and	and	CCONJ
dti-1424	133	12	has	have	AUX
dti-1424	133	13	previously	previously	ADV
dti-1424	133	14	worked	work	VERB
dti-1424	133	15	at	at	ADP
dti-1424	133	16	the	the	DET
dti-1424	133	17	mcgowan	mcgowan	PROPN
dti-1424	133	18	institute	institute	PROPN
dti-1424	133	19	for	for	ADP
dti-1424	133	20	regenerative	regenerative	ADJ
dti-1424	133	21	medicine	medicine	NOUN
dti-1424	133	22	at	at	ADP
dti-1424	133	23	the	the	DET
dti-1424	133	24	university	university	PROPN
dti-1424	133	25	of	of	ADP
dti-1424	133	26	pittsburgh	pittsburgh	PROPN
dti-1424	133	27	medical	medical	ADJ
dti-1424	133	28	center	center	PROPN
dti-1424	133	29	(	(	PUNCT
dti-1424	133	30	usa	usa	PROPN
dti-1424	133	31	)	)	PUNCT
dti-1424	133	32	,	,	PUNCT
dti-1424	133	33	the	the	DET
dti-1424	133	34	new	new	PROPN
dti-1424	133	35	york	york	PROPN
dti-1424	133	36	presbyterian	presbyterian	PROPN
dti-1424	133	37	and	and	CCONJ
dti-1424	133	38	columbia	columbia	PROPN
dti-1424	133	39	university	university	PROPN
dti-1424	133	40	hospital	hospital	NOUN
dti-1424	133	41	(	(	PUNCT
dti-1424	133	42	usa	usa	PROPN
dti-1424	133	43	)	)	PUNCT
dti-1424	133	44	,	,	PUNCT
dti-1424	133	45	the	the	DET
dti-1424	133	46	cardiovascular	cardiovascular	ADJ
dti-1424	133	47	surgery	surgery	NOUN
dti-1424	133	48	department	department	NOUN
dti-1424	133	49	of	of	ADP
dti-1424	133	50	university	university	PROPN
dti-1424	133	51	of	of	ADP
dti-1424	133	52	leuven	leuven	PROPN
dti-1424	133	53	(	(	PUNCT
dti-1424	133	54	belgium	belgium	NOUN
dti-1424	133	55	)	)	PUNCT
dti-1424	133	56	,	,	PUNCT
dti-1424	133	57	the	the	DET
dti-1424	133	58	campus	campus	PROPN
dti-1424	133	59	st	st	PROPN
dti-1424	133	60	jan	jan	PROPN
dti-1424	133	61	hospital	hospital	PROPN
dti-1424	133	62	osot	osot	PROPN
dti-1424	133	63	-	-	PUNCT
dti-1424	133	64	limburg	limburg	PROPN
dti-1424	133	65	in	in	ADP
dti-1424	133	66	genk	genk	PROPN
dti-1424	133	67	(	(	PUNCT
dti-1424	133	68	belgium	belgium	PROPN
dti-1424	133	69	)	)	PUNCT
dti-1424	133	70	and	and	CCONJ
dti-1424	133	71	at	at	ADP
dti-1424	133	72	the	the	DET
dti-1424	133	73	university	university	NOUN
dti-1424	133	74	campus	campus	NOUN
dti-1424	133	75	biomedico	biomedico	NOUN
dti-1424	133	76	of	of	ADP
dti-1424	133	77	rome	rome	PROPN
dti-1424	133	78	,	,	PUNCT
dti-1424	133	79	italy	italy	PROPN
dti-1424	133	80	.	.	PUNCT
dti-1424	134	1	he	he	PRON
dti-1424	134	2	now	now	ADV
dti-1424	134	3	works	work	VERB
dti-1424	134	4	primarily	primarily	ADV
dti-1424	134	5	in	in	ADP
dti-1424	134	6	the	the	DET
dti-1424	134	7	field	field	NOUN
dti-1424	134	8	of	of	ADP
dti-1424	134	9	translational	translational	ADJ
dti-1424	134	10	research	research	NOUN
dti-1424	134	11	and	and	CCONJ
dti-1424	134	12	clinical	clinical	ADJ
dti-1424	134	13	in	in	ADP
dti-1424	134	14	cardiovascular	cardiovascular	ADJ
dti-1424	134	15	surgery	surgery	NOUN
dti-1424	134	16	,	,	PUNCT
dti-1424	134	17	in	in	ADP
dti-1424	134	18	tissue	tissue	NOUN
dti-1424	134	19	engineering	engineering	NOUN
dti-1424	134	20	and	and	CCONJ
dti-1424	134	21	regenerative	regenerative	ADJ
dti-1424	134	22	medicine	medicine	NOUN
dti-1424	134	23	.	.	PUNCT
dti-1424	135	1	dr	dr	PROPN
dti-1424	135	2	.	.	PROPN
dti-1424	135	3	spadaccio	spadaccio	PROPN
dti-1424	135	4	is	be	AUX
dti-1424	135	5	the	the	DET
dti-1424	135	6	author	author	NOUN
dti-1424	135	7	or	or	CCONJ
dti-1424	135	8	co	co	NOUN
dti-1424	135	9	-	-	NOUN
dti-1424	135	10	author	author	NOUN
dti-1424	135	11	of	of	ADP
dti-1424	135	12	more	more	ADJ
dti-1424	135	13	than	than	ADP
dti-1424	135	14	60	60	NUM
dti-1424	135	15	pubmed	pubmed	NOUN
dti-1424	135	16	-	-	PUNCT
dti-1424	135	17	indexed	index	VERB
dti-1424	135	18	published	publish	VERB
dti-1424	135	19	papers	paper	NOUN
dti-1424	135	20	and	and	CCONJ
dti-1424	135	21	has	have	AUX
dti-1424	135	22	presented	present	VERB
dti-1424	135	23	more	more	ADJ
dti-1424	135	24	than	than	ADP
dti-1424	135	25	60	60	NUM
dti-1424	135	26	abstracts	abstract	NOUN
dti-1424	135	27	and	and	CCONJ
dti-1424	135	28	personal	personal	ADJ
dti-1424	135	29	communications	communication	NOUN
dti-1424	135	30	at	at	ADP
dti-1424	135	31	conferences	conference	NOUN
dti-1424	135	32	,	,	PUNCT
dti-1424	135	33	being	be	AUX
dti-1424	135	34	involved	involve	VERB
dti-1424	135	35	in	in	ADP
dti-1424	135	36	organization	organization	NOUN
dti-1424	135	37	of	of	ADP
dti-1424	135	38	meetings	meeting	NOUN
dti-1424	135	39	and	and	CCONJ
dti-1424	135	40	chairing	chairing	NOUN
dti-1424	135	41	of	of	ADP
dti-1424	135	42	sessions	session	NOUN
dti-1424	135	43	as	as	ADP
dti-1424	135	44	moderator	moderator	NOUN
dti-1424	135	45	.	.	PUNCT
dti-1424	136	1	he	he	PRON
dti-1424	136	2	holds	hold	VERB
dti-1424	136	3	editorial	editorial	ADJ
dti-1424	136	4	appointments	appointment	NOUN
dti-1424	136	5	at	at	ADP
dti-1424	136	6	the	the	DET
dti-1424	136	7	journal	journal	ADJ
dti-1424	136	8	artificial	artificial	ADJ
dti-1424	136	9	organs	organ	NOUN
dti-1424	136	10	.	.	PUNCT
dti-1424	137	1	cristianospadaccio@gmail.com	cristianospadaccio@gmail.com	X
dti-1424	138	1	institutional	institutional	ADJ
dti-1424	138	2	webpage	webpage	NOUN
dti-1424	138	3	http://www.gla.ac.uk/researchinstitutes/icams/	http://www.gla.ac.uk/researchinstitutes/icams/	NOUN
dti-1424	138	4	staff/?action	staff/?action	NOUN
dti-1424	138	5	=	=	SYM
dti-1424	138	6	person&id=4edcedec8393	person&id=4edcedec8393	NOUN
dti-1424	138	7	lead	lead	NOUN
dti-1424	138	8	guest	guest	NOUN
dti-1424	138	9	editor	editor	NOUN
dti-1424	138	10	dr	dr	PROPN
dti-1424	138	11	.	.	PROPN
dti-1424	138	12	cristiano	cristiano	PROPN
dti-1424	138	13	spadaccio	spadaccio	PROPN
dti-1424	138	14	guest	guest	PROPN
dti-1424	138	15	editors	editors	PROPN
dti-1424	138	16	dr	dr	PROPN
dti-1424	138	17	.	.	PROPN
dti-1424	138	18	nicola	nicola	PROPN
dti-1424	138	19	testa	testa	PROPN
dti-1424	138	20	cardiovascular	cardiovascular	ADJ
dti-1424	138	21	surgeon	surgeon	NOUN
dti-1424	138	22	of	of	ADP
dti-1424	138	23	italy	italy	PROPN
dti-1424	138	24	at	at	ADP
dti-1424	138	25	john	john	PROPN
dti-1424	138	26	paul	paul	PROPN
dti-1424	138	27	ii	ii	PROPN
dti-1424	138	28	foundation	foundation	PROPN
dti-1424	138	29	—	—	PUNCT
dti-1424	138	30	catholic	catholic	PROPN
dti-1424	138	31	university	university	PROPN
dti-1424	138	32	in	in	ADP
dti-1424	138	33	campobasso	campobasso	NOUN
dti-1424	138	34	.	.	PUNCT
dti-1424	139	1	he	he	PRON
dti-1424	139	2	completed	complete	VERB
dti-1424	139	3	his	his	PRON
dti-1424	139	4	md	md	PROPN
dti-1424	139	5	degree	degree	NOUN
dti-1424	139	6	at	at	ADP
dti-1424	139	7	catholic	catholic	PROPN
dti-1424	139	8	university	university	PROPN
dti-1424	139	9	of	of	ADP
dti-1424	139	10	sacred	sacred	ADJ
dti-1424	139	11	heart	heart	NOUN
dti-1424	139	12	in	in	ADP
dti-1424	139	13	rome	rome	PROPN
dti-1424	139	14	(	(	PUNCT
dti-1424	139	15	2003	2003	NUM
dti-1424	139	16	)	)	PUNCT
dti-1424	139	17	and	and	CCONJ
dti-1424	139	18	cardiac	cardiac	ADJ
dti-1424	139	19	surgery	surgery	NOUN
dti-1424	139	20	residency	residency	NOUN
dti-1424	139	21	at	at	ADP
dti-1424	139	22	catholic	catholic	PROPN
dti-1424	139	23	university	university	PROPN
dti-1424	139	24	of	of	ADP
dti-1424	139	25	sacred	sacred	ADJ
dti-1424	139	26	heart	heart	NOUN
dti-1424	139	27	in	in	ADP
dti-1424	139	28	rome	rome	PROPN
dti-1424	139	29	(	(	PUNCT
dti-1424	139	30	2008	2008	NUM
dti-1424	139	31	)	)	PUNCT
dti-1424	139	32	he	he	PRON
dti-1424	139	33	has	have	AUX
dti-1424	139	34	previously	previously	ADV
dti-1424	139	35	worked	work	VERB
dti-1424	139	36	as	as	ADP
dti-1424	139	37	staff	staff	NOUN
dti-1424	139	38	cardiac	cardiac	ADJ
dti-1424	139	39	surgeon	surgeon	NOUN
dti-1424	139	40	in	in	ADP
dti-1424	139	41	cardiovascular	cardiovascular	ADJ
dti-1424	139	42	surgery	surgery	NOUN
dti-1424	139	43	unit	unit	NOUN
dti-1424	139	44	—	—	PUNCT
dti-1424	139	45	catholic	catholic	PROPN
dti-1424	139	46	university	university	PROPN
dti-1424	139	47	in	in	ADP
dti-1424	139	48	campobasso	campobasso	NOUN
dti-1424	139	49	(	(	PUNCT
dti-1424	139	50	2008–2013	2008–2013	NUM
dti-1424	139	51	)	)	PUNCT
dti-1424	139	52	and	and	CCONJ
dti-1424	139	53	in	in	ADP
dti-1424	139	54	cardiac	cardiac	ADJ
dti-1424	139	55	surgery	surgery	NOUN
dti-1424	139	56	unit	unit	NOUN
dti-1424	139	57	“	"	PUNCT
dti-1424	139	58	ss.annunziata	ss.annunziata	PROPN
dti-1424	139	59	hospital	hospital	NOUN
dti-1424	139	60	”	"	PUNCT
dti-1424	139	61	chieti	chieti	PROPN
dti-1424	139	62	(	(	PUNCT
dti-1424	139	63	2013–2014	2013–2014	NUM
dti-1424	139	64	)	)	PUNCT
dti-1424	139	65	.	.	PUNCT
dti-1424	140	1	he	he	PRON
dti-1424	140	2	now	now	ADV
dti-1424	140	3	works	work	VERB
dti-1424	140	4	primarily	primarily	ADV
dti-1424	140	5	in	in	ADP
dti-1424	140	6	heart	heart	NOUN
dti-1424	140	7	failure	failure	NOUN
dti-1424	140	8	treatment	treatment	NOUN
dti-1424	140	9	and	and	CCONJ
dti-1424	140	10	research	research	NOUN
dti-1424	140	11	and	and	CCONJ
dti-1424	140	12	surgical	surgical	ADJ
dti-1424	140	13	atrial	atrial	ADJ
dti-1424	140	14	fibrillation	fibrillation	NOUN
dti-1424	140	15	ablation	ablation	NOUN
dti-1424	140	16	.	.	PUNCT
dti-1424	141	1	dr	dr	PROPN
dti-1424	141	2	.	.	PROPN
dti-1424	141	3	testa	testa	PROPN
dti-1424	141	4	is	be	AUX
dti-1424	141	5	the	the	DET
dti-1424	141	6	author	author	NOUN
dti-1424	141	7	or	or	CCONJ
dti-1424	141	8	co	co	NOUN
dti-1424	141	9	-	-	NOUN
dti-1424	141	10	author	author	NOUN
dti-1424	141	11	of	of	ADP
dti-1424	141	12	more	more	ADJ
dti-1424	141	13	than	than	ADP
dti-1424	141	14	30	30	NUM
dti-1424	141	15	published	publish	VERB
dti-1424	141	16	papers	paper	NOUN
dti-1424	141	17	and	and	CCONJ
dti-1424	141	18	has	have	AUX
dti-1424	141	19	presented	present	VERB
dti-1424	141	20	at	at	ADP
dti-1424	141	21	more	more	ADJ
dti-1424	141	22	than	than	ADP
dti-1424	141	23	30	30	NUM
dti-1424	141	24	conferences	conference	NOUN
dti-1424	141	25	.	.	PUNCT
dti-1424	142	1	ntesta.cch@gmail.com	ntesta.cch@gmail.com	X
dti-1424	143	1	institutional	institutional	ADJ
dti-1424	143	2	webpage	webpage	NOUN
dti-1424	143	3	http://www.fgps.it/index.php/i-dipartimenti/	http://www.fgps.it/index.php/i-dipartimenti/	NOUN
dti-1424	143	4	malattie	malattie	NOUN
dti-1424	143	5	-	-	PUNCT
dti-1424	143	6	cardiovascolari	cardiovascolari	NOUN
dti-1424	143	7	-	-	PUNCT
dti-1424	143	8	e	e	NOUN
dti-1424	143	9	-	-	NOUN
dti-1424	143	10	dei	dei	ADJ
dti-1424	143	11	-	-	PUNCT
dti-1424	143	12	grossi	grossi	ADJ
dti-1424	143	13	-	-	PUNCT
dti-1424	143	14	vasi/	vasi/	NUM
dti-1424	143	15	personale	personale	NOUN
dti-1424	143	16	http://www.la-press.com/drug-target-insights-journal-j23	http://www.la-press.com/drug-target-insights-journal-j23	PROPN
dti-1424	143	17	http://www.la-press.com	http://www.la-press.com	X
dti-1424	144	1	mailto:cristianospadaccio@gmail.com	mailto:cristianospadaccio@gmail.com	PROPN
dti-1424	144	2	http://www.gla.ac.uk/researchinstitutes/icams/staff/?action=person&id=4edcedec8393	http://www.gla.ac.uk/researchinstitutes/icams/staff/?action=person&id=4edcedec8393	PROPN
dti-1424	144	3	http://www.gla.ac.uk/researchinstitutes/icams/staff/?action=person&id=4edcedec8393	http://www.gla.ac.uk/researchinstitutes/icams/staff/?action=person&id=4edcedec8393	PROPN
dti-1424	144	4	mailto:ntesta.cch@gmail.com	mailto:ntesta.cch@gmail.com	PROPN
dti-1424	144	5	http://www.fgps.it/index.php/i-dipartimenti/malattie-cardiovascolari-e-dei-grossi-vasi/personale	http://www.fgps.it/index.php/i-dipartimenti/malattie-cardiovascolari-e-dei-grossi-vasi/personale	PROPN
dti-1424	144	6	http://www.fgps.it/index.php/i-dipartimenti/malattie-cardiovascolari-e-dei-grossi-vasi/personale	http://www.fgps.it/index.php/i-dipartimenti/malattie-cardiovascolari-e-dei-grossi-vasi/personale	ADJ
dti-1424	144	7	http://www.fgps.it/index.php/i-dipartimenti/malattie-cardiovascolari-e-dei-grossi-vasi/personale	http://www.fgps.it/index.php/i-dipartimenti/malattie-cardiovascolari-e-dei-grossi-vasi/personale	NOUN
dti-1424	144	8	drug	drug	NOUN
dti-1424	144	9	target	target	NOUN
dti-1424	144	10	insights	insight	NOUN
dti-1424	144	11	drug	drug	NOUN
dti-1424	144	12	target	target	NOUN
dti-1424	144	13	insights	insight	NOUN
dti-1424	144	14	2016:10(s1	2016:10(s1	NUM
dti-1424	144	15	)	)	PUNCT
dti-1424	144	16	19	19	NUM
dti-1424	144	17	dr	dr	PROPN
dti-1424	144	18	.	.	PROPN
dti-1424	144	19	francesco	francesco	PROPN
dti-1424	144	20	nappi	nappi	PROPN
dti-1424	144	21	cardiovascular	cardiovascular	ADJ
dti-1424	144	22	surgeon	surgeon	NOUN
dti-1424	144	23	at	at	ADP
dti-1424	144	24	centre	centre	NOUN
dti-1424	144	25	cardiologique	cardiologique	PROPN
dti-1424	144	26	du	du	PROPN
dti-1424	144	27	nord	nord	PROPN
dti-1424	144	28	,	,	PUNCT
dti-1424	144	29	paris	paris	PROPN
dti-1424	144	30	,	,	PUNCT
dti-1424	144	31	france	france	PROPN
dti-1424	144	32	.	.	PUNCT
dti-1424	145	1	he	he	PRON
dti-1424	145	2	completed	complete	VERB
dti-1424	145	3	his	his	PRON
dti-1424	145	4	md	md	PROPN
dti-1424	145	5	at	at	ADP
dti-1424	145	6	university	university	PROPN
dti-1424	145	7	federico	federico	PROPN
dti-1424	145	8	ii	ii	PROPN
dti-1424	145	9	of	of	ADP
dti-1424	145	10	naples	naples	PROPN
dti-1424	145	11	and	and	CCONJ
dti-1424	145	12	has	have	AUX
dti-1424	145	13	previously	previously	ADV
dti-1424	145	14	worked	work	VERB
dti-1424	145	15	as	as	ADP
dti-1424	145	16	a	a	DET
dti-1424	145	17	surgeon	surgeon	NOUN
dti-1424	145	18	and	and	CCONJ
dti-1424	145	19	as	as	ADP
dti-1424	145	20	a	a	DET
dti-1424	145	21	researcher	researcher	NOUN
dti-1424	145	22	in	in	ADP
dti-1424	145	23	this	this	DET
dti-1424	145	24	institution	institution	NOUN
dti-1424	145	25	.	.	PUNCT
dti-1424	146	1	he	he	PRON
dti-1424	146	2	now	now	ADV
dti-1424	146	3	works	work	VERB
dti-1424	146	4	primarily	primarily	ADV
dti-1424	146	5	in	in	ADP
dti-1424	146	6	cardiovascular	cardiovascular	ADJ
dti-1424	146	7	disease	disease	NOUN
dti-1424	146	8	and	and	CCONJ
dti-1424	146	9	translational	translational	ADJ
dti-1424	146	10	medicine	medicine	NOUN
dti-1424	146	11	.	.	PUNCT
dti-1424	147	1	dr	dr	PROPN
dti-1424	147	2	.	.	PROPN
dti-1424	147	3	nappi	nappi	PROPN
dti-1424	147	4	is	be	AUX
dti-1424	147	5	the	the	DET
dti-1424	147	6	author	author	NOUN
dti-1424	147	7	or	or	CCONJ
dti-1424	147	8	co	co	NOUN
dti-1424	147	9	-	-	NOUN
dti-1424	147	10	author	author	NOUN
dti-1424	147	11	of	of	ADP
dti-1424	147	12	40	40	NUM
dti-1424	147	13	published	publish	VERB
dti-1424	147	14	papers	paper	NOUN
dti-1424	147	15	and	and	CCONJ
dti-1424	147	16	has	have	AUX
dti-1424	147	17	presented	present	VERB
dti-1424	147	18	at	at	ADP
dti-1424	147	19	over	over	ADP
dti-1424	147	20	30	30	NUM
dti-1424	147	21	conferences	conference	NOUN
dti-1424	147	22	,	,	PUNCT
dti-1424	147	23	and	and	CCONJ
dti-1424	147	24	holds	hold	VERB
dti-1424	147	25	editorial	editorial	ADJ
dti-1424	147	26	appointments	appointment	NOUN
dti-1424	147	27	at	at	ADP
dti-1424	147	28	the	the	DET
dti-1424	147	29	journal	journal	NOUN
dti-1424	147	30	of	of	ADP
dti-1424	147	31	thoracic	thoracic	NOUN
dti-1424	147	32	disease	disease	NOUN
dti-1424	147	33	.	.	PUNCT
dti-1424	148	1	francesconappi@gmail.com	francesconappi@gmail.com	PROPN
dti-1424	148	2	dr	dr	PROPN
dti-1424	148	3	.	.	PROPN
dti-1424	148	4	alberto	alberto	PROPN
dti-1424	148	5	rainer	rainer	PROPN
dti-1424	148	6	assistant	assistant	PROPN
dti-1424	148	7	professor	professor	NOUN
dti-1424	148	8	in	in	ADP
dti-1424	148	9	chemical	chemical	ADJ
dti-1424	148	10	fundamentals	fundamental	NOUN
dti-1424	148	11	of	of	ADP
dti-1424	148	12	technologies	technology	NOUN
dti-1424	148	13	at	at	ADP
dti-1424	148	14	università	università	PROPN
dti-1424	148	15	campus	campus	PROPN
dti-1424	148	16	bio	bio	PROPN
dti-1424	148	17	-	-	ADJ
dti-1424	148	18	medico	medico	ADJ
dti-1424	148	19	di	di	X
dti-1424	148	20	roma	roma	PROPN
dti-1424	148	21	,	,	PUNCT
dti-1424	148	22	italy	italy	PROPN
dti-1424	148	23	.	.	PUNCT
dti-1424	149	1	he	he	PRON
dti-1424	149	2	completed	complete	VERB
dti-1424	149	3	his	his	PRON
dti-1424	149	4	phd	phd	NOUN
dti-1424	149	5	at	at	ADP
dti-1424	149	6	university	university	NOUN
dti-1424	149	7	tor	tor	NOUN
dti-1424	149	8	vergata	vergata	PROPN
dti-1424	149	9	of	of	ADP
dti-1424	149	10	rome	rome	PROPN
dti-1424	149	11	and	and	CCONJ
dti-1424	149	12	has	have	AUX
dti-1424	149	13	previously	previously	ADV
dti-1424	149	14	worked	work	VERB
dti-1424	149	15	at	at	ADP
dti-1424	149	16	the	the	DET
dti-1424	149	17	university	university	NOUN
dti-1424	149	18	of	of	ADP
dti-1424	149	19	rome	rome	PROPN
dti-1424	149	20	and	and	CCONJ
dti-1424	149	21	triest	tri	ADJ
dti-1424	149	22	.	.	PUNCT
dti-1424	150	1	he	he	PRON
dti-1424	150	2	now	now	ADV
dti-1424	150	3	works	work	VERB
dti-1424	150	4	primarily	primarily	ADV
dti-1424	150	5	in	in	ADP
dti-1424	150	6	tissue	tissue	NOUN
dti-1424	150	7	engineering	engineering	NOUN
dti-1424	150	8	,	,	PUNCT
dti-1424	150	9	biofunctionalization	biofunctionalization	NOUN
dti-1424	150	10	of	of	ADP
dti-1424	150	11	polymers	polymer	NOUN
dti-1424	150	12	and	and	CCONJ
dti-1424	150	13	analysis	analysis	NOUN
dti-1424	150	14	of	of	ADP
dti-1424	150	15	cell	cell	NOUN
dti-1424	150	16	-	-	PUNCT
dti-1424	150	17	to	to	ADP
dti-1424	150	18	-	-	PUNCT
dti-1424	150	19	cell	cell	NOUN
dti-1424	150	20	interaction	interaction	NOUN
dti-1424	150	21	on	on	ADP
dti-1424	150	22	micro	micro	ADJ
dti-1424	150	23	chips	chip	NOUN
dti-1424	150	24	.	.	PUNCT
dti-1424	151	1	dr	dr	PROPN
dti-1424	151	2	.	.	PROPN
dti-1424	151	3	rainer	rainer	PROPN
dti-1424	151	4	is	be	AUX
dti-1424	151	5	the	the	DET
dti-1424	151	6	author	author	NOUN
dti-1424	151	7	or	or	CCONJ
dti-1424	151	8	co	co	NOUN
dti-1424	151	9	-	-	NOUN
dti-1424	151	10	author	author	NOUN
dti-1424	151	11	of	of	ADP
dti-1424	151	12	over	over	ADP
dti-1424	151	13	30	30	NUM
dti-1424	151	14	published	publish	VERB
dti-1424	151	15	papers	paper	NOUN
dti-1424	151	16	and	and	CCONJ
dti-1424	151	17	has	have	AUX
dti-1424	151	18	presented	present	VERB
dti-1424	151	19	at	at	ADP
dti-1424	151	20	over	over	ADP
dti-1424	151	21	40	40	NUM
dti-1424	151	22	conferences	conference	NOUN
dti-1424	151	23	,	,	PUNCT
dti-1424	151	24	and	and	CCONJ
dti-1424	151	25	holds	hold	VERB
dti-1424	151	26	editorial	editorial	ADJ
dti-1424	151	27	appointments	appointment	NOUN
dti-1424	151	28	at	at	ADP
dti-1424	151	29	the	the	DET
dti-1424	151	30	journal	journal	ADJ
dti-1424	151	31	artificial	artificial	ADJ
dti-1424	151	32	organs	organ	NOUN
dti-1424	151	33	.	.	PUNCT
dti-1424	152	1	a.rainer@unicampus.it	a.rainer@unicampus.it	VERB
dti-1424	152	2	institutional	institutional	ADJ
dti-1424	152	3	webpage	webpage	NOUN
dti-1424	152	4	http://didattica.unicampus.it/didattica/guide/	http://didattica.unicampus.it/didattica/guide/	PROPN
dti-1424	152	5	paginadocente.do;jsessionid	paginadocente.do;jsessionid	PROPN
dti-1424	152	6	=	=	PROPN
dti-1424	152	7	bb5df6e681779e9	bb5df6e681779e9	PUNCT
dti-1424	152	8	a0d9ee809d4665e1a.jvm1a?docente_id=325	a0d9ee809d4665e1a.jvm1a?docente_id=325	PROPN
dti-1424	152	9	dr	dr	PROPN
dti-1424	152	10	.	.	PROPN
dti-1424	152	11	vito	vito	PROPN
dti-1424	152	12	d.	d.	PROPN
dti-1424	152	13	bruno	bruno	PROPN
dti-1424	152	14	senior	senior	ADJ
dti-1424	152	15	registrar	registrar	NOUN
dti-1424	152	16	in	in	ADP
dti-1424	152	17	cardiac	cardiac	ADJ
dti-1424	152	18	surgery	surgery	NOUN
dti-1424	152	19	at	at	ADP
dti-1424	152	20	university	university	NOUN
dti-1424	152	21	hospitals	hospital	NOUN
dti-1424	152	22	of	of	ADP
dti-1424	152	23	bristol	bristol	PROPN
dti-1424	152	24	and	and	CCONJ
dti-1424	152	25	research	research	NOUN
dti-1424	152	26	associate	associate	NOUN
dti-1424	152	27	fellow	fellow	NOUN
dti-1424	152	28	at	at	ADP
dti-1424	152	29	the	the	DET
dti-1424	152	30	department	department	NOUN
dti-1424	152	31	of	of	ADP
dti-1424	152	32	clinical	clinical	ADJ
dti-1424	152	33	science	science	NOUN
dti-1424	152	34	at	at	ADP
dti-1424	152	35	university	university	PROPN
dti-1424	152	36	of	of	ADP
dti-1424	152	37	bristol	bristol	PROPN
dti-1424	152	38	(	(	PUNCT
dti-1424	152	39	uk	uk	PROPN
dti-1424	152	40	)	)	PUNCT
dti-1424	152	41	.	.	PUNCT
dti-1424	153	1	he	he	PRON
dti-1424	153	2	completed	complete	VERB
dti-1424	153	3	his	his	PRON
dti-1424	153	4	phd	phd	NOUN
dti-1424	153	5	in	in	ADP
dti-1424	153	6	surgery	surgery	NOUN
dti-1424	153	7	and	and	CCONJ
dti-1424	153	8	surgical	surgical	ADJ
dti-1424	153	9	biotechnology	biotechnology	NOUN
dti-1424	153	10	at	at	ADP
dti-1424	153	11	university	university	PROPN
dti-1424	153	12	of	of	ADP
dti-1424	153	13	insubria	insubria	PROPN
dti-1424	153	14	,	,	PUNCT
dti-1424	153	15	varese	varese	PROPN
dti-1424	153	16	(	(	PUNCT
dti-1424	153	17	italy	italy	PROPN
dti-1424	153	18	)	)	PUNCT
dti-1424	153	19	.	.	PUNCT
dti-1424	154	1	he	he	PRON
dti-1424	154	2	has	have	AUX
dti-1424	154	3	previously	previously	ADV
dti-1424	154	4	worked	work	VERB
dti-1424	154	5	at	at	ADP
dti-1424	154	6	varese	varese	PROPN
dti-1424	154	7	university	university	PROPN
dti-1424	154	8	hospital	hospital	NOUN
dti-1424	154	9	(	(	PUNCT
dti-1424	154	10	varese	varese	PROPN
dti-1424	154	11	—	—	PUNCT
dti-1424	154	12	italy	italy	PROPN
dti-1424	154	13	)	)	PUNCT
dti-1424	154	14	and	and	CCONJ
dti-1424	154	15	cardiocentro	cardiocentro	NOUN
dti-1424	154	16	ticino	ticino	PROPN
dti-1424	154	17	(	(	PUNCT
dti-1424	154	18	lugano	lugano	PROPN
dti-1424	154	19	—	—	PUNCT
dti-1424	154	20	switzerland	switzerland	PROPN
dti-1424	154	21	.	.	PUNCT
dti-1424	154	22	)	)	PUNCT
dti-1424	155	1	he	he	PRON
dti-1424	155	2	now	now	ADV
dti-1424	155	3	works	work	VERB
dti-1424	155	4	primarily	primarily	ADV
dti-1424	155	5	in	in	ADP
dti-1424	155	6	clinical	clinical	ADJ
dti-1424	155	7	and	and	CCONJ
dti-1424	155	8	translational	translational	ADJ
dti-1424	155	9	research	research	NOUN
dti-1424	155	10	in	in	ADP
dti-1424	155	11	cardiac	cardiac	ADJ
dti-1424	155	12	surgery	surgery	NOUN
dti-1424	155	13	and	and	CCONJ
dti-1424	155	14	cardiology	cardiology	NOUN
dti-1424	155	15	.	.	PUNCT
dti-1424	156	1	dr	dr	PROPN
dti-1424	156	2	.	.	PROPN
dti-1424	156	3	bruno	bruno	PROPN
dti-1424	156	4	is	be	AUX
dti-1424	156	5	the	the	DET
dti-1424	156	6	author	author	NOUN
dti-1424	156	7	or	or	CCONJ
dti-1424	156	8	co	co	NOUN
dti-1424	156	9	-	-	NOUN
dti-1424	156	10	author	author	NOUN
dti-1424	156	11	of	of	ADP
dti-1424	156	12	23	23	NUM
dti-1424	156	13	pubmed	pubmed	PROPN
dti-1424	156	14	cited	cite	VERB
dti-1424	156	15	papers	paper	NOUN
dti-1424	156	16	and	and	CCONJ
dti-1424	156	17	more	more	ADJ
dti-1424	156	18	than	than	ADP
dti-1424	156	19	30	30	NUM
dti-1424	156	20	abstracts	abstract	NOUN
dti-1424	156	21	for	for	ADP
dti-1424	156	22	national	national	ADJ
dti-1424	156	23	and	and	CCONJ
dti-1424	156	24	international	international	ADJ
dti-1424	156	25	meetings	meeting	NOUN
dti-1424	156	26	.	.	PUNCT
dti-1424	157	1	he	he	PRON
dti-1424	157	2	is	be	AUX
dti-1424	157	3	section	section	NOUN
dti-1424	157	4	editor	editor	NOUN
dti-1424	157	5	at	at	ADP
dti-1424	157	6	archives	archive	NOUN
dti-1424	157	7	of	of	ADP
dti-1424	157	8	medical	medical	ADJ
dti-1424	157	9	science	science	NOUN
dti-1424	157	10	—	—	PUNCT
dti-1424	157	11	civilisation	civilisation	NOUN
dti-1424	157	12	disease	disease	NOUN
dti-1424	157	13	.	.	PUNCT
dti-1424	158	1	mddvb@bristol.ac.uk	mddvb@bristol.ac.uk	ADJ
dti-1424	158	2	institutional	institutional	ADJ
dti-1424	158	3	webpage	webpage	NOUN
dti-1424	158	4	http://www.bris.ac.uk/clinical-sciences/	http://www.bris.ac.uk/clinical-sciences/	NOUN
dti-1424	158	5	people/182709	people/182709	NOUN
dti-1424	158	6	/	/	SYM
dti-1424	158	7	index.html	index.html	VERB
dti-1424	158	8	supplement	supplement	NOUN
dti-1424	158	9	title	title	NOUN
dti-1424	158	10	:	:	PUNCT
dti-1424	158	11	current	current	ADJ
dti-1424	158	12	developments	development	NOUN
dti-1424	158	13	in	in	ADP
dti-1424	158	14	drug	drug	NOUN
dti-1424	158	15	eluting	eluting	NOUN
dti-1424	158	16	devices	device	NOUN
dti-1424	158	17	citation	citation	NOUN
dti-1424	158	18	:	:	PUNCT
dti-1424	158	19	spadaccio	spadaccio	PROPN
dti-1424	158	20	et	et	PROPN
dti-1424	158	21	al	al	PROPN
dti-1424	158	22	.	.	PUNCT
dti-1424	159	1	current	current	ADJ
dti-1424	159	2	developments	development	NOUN
dti-1424	159	3	in	in	ADP
dti-1424	159	4	drug	drug	NOUN
dti-1424	159	5	eluting	eluting	NOUN
dti-1424	159	6	devices	device	NOUN
dti-1424	159	7	.	.	PUNCT
dti-1424	160	1	drug	drug	NOUN
dti-1424	160	2	target	target	NOUN
dti-1424	160	3	insights	insight	NOUN
dti-1424	160	4	2016:10(s1	2016:10(s1	NUM
dti-1424	160	5	)	)	PUNCT
dti-1424	160	6	15–19	15–19	NUM
dti-1424	160	7	doi:10.4137	doi:10.4137	NOUN
dti-1424	160	8	/	/	SYM
dti-1424	160	9	dti.s41240	dti.s41240	PROPN
dti-1424	160	10	.	.	PUNCT
dti-1424	161	1	type	type	NOUN
dti-1424	161	2	:	:	PUNCT
dti-1424	161	3	editorial	editorial	NOUN
dti-1424	161	4	funding	funding	NOUN
dti-1424	161	5	:	:	PUNCT
dti-1424	161	6	authors	author	NOUN
dti-1424	161	7	disclose	disclose	VERB
dti-1424	161	8	no	no	DET
dti-1424	161	9	external	external	ADJ
dti-1424	161	10	funding	funding	NOUN
dti-1424	161	11	sources	source	NOUN
dti-1424	161	12	.	.	PUNCT
dti-1424	162	1	competing	compete	VERB
dti-1424	162	2	interests	interest	NOUN
dti-1424	162	3	:	:	PUNCT
dti-1424	162	4	authors	author	NOUN
dti-1424	162	5	disclose	disclose	VERB
dti-1424	162	6	no	no	DET
dti-1424	162	7	potential	potential	ADJ
dti-1424	162	8	conflicts	conflict	NOUN
dti-1424	162	9	of	of	ADP
dti-1424	162	10	interest	interest	NOUN
dti-1424	162	11	.	.	PUNCT
dti-1424	163	1	copyright	copyright	NOUN
dti-1424	163	2	:	:	PUNCT
dti-1424	163	3	©	©	PROPN
dti-1424	163	4	the	the	DET
dti-1424	163	5	authors	author	NOUN
dti-1424	163	6	,	,	PUNCT
dti-1424	163	7	publisher	publisher	NOUN
dti-1424	163	8	and	and	CCONJ
dti-1424	163	9	licensee	licensee	NOUN
dti-1424	163	10	libertas	liberta	NOUN
dti-1424	163	11	academica	academica	PROPN
dti-1424	163	12	limited	limit	VERB
dti-1424	163	13	.	.	PUNCT
dti-1424	164	1	this	this	PRON
dti-1424	164	2	is	be	AUX
dti-1424	164	3	an	an	DET
dti-1424	164	4	open	open	ADJ
dti-1424	164	5	-	-	PUNCT
dti-1424	164	6	access	access	NOUN
dti-1424	164	7	article	article	NOUN
dti-1424	164	8	distributed	distribute	VERB
dti-1424	164	9	under	under	ADP
dti-1424	164	10	the	the	DET
dti-1424	164	11	terms	term	NOUN
dti-1424	164	12	of	of	ADP
dti-1424	164	13	the	the	DET
dti-1424	164	14	creative	creative	ADJ
dti-1424	164	15	commons	common	NOUN
dti-1424	164	16	cc	cc	NOUN
dti-1424	164	17	-	-	PUNCT
dti-1424	164	18	by	by	ADP
dti-1424	164	19	-	-	PUNCT
dti-1424	164	20	nc3.0	nc3.0	ADP
dti-1424	164	21	license	license	NOUN
dti-1424	164	22	.	.	PUNCT
dti-1424	165	1	correspondence	correspondence	NOUN
dti-1424	165	2	:	:	PUNCT
dti-1424	165	3	cristianospadaccio@gmail.com	cristianospadaccio@gmail.com	X
dti-1424	166	1	all	all	DET
dti-1424	166	2	authors	author	NOUN
dti-1424	166	3	have	have	AUX
dti-1424	166	4	provided	provide	VERB
dti-1424	166	5	signed	sign	VERB
dti-1424	166	6	confirmation	confirmation	NOUN
dti-1424	166	7	of	of	ADP
dti-1424	166	8	their	their	PRON
dti-1424	166	9	compliance	compliance	NOUN
dti-1424	166	10	with	with	ADP
dti-1424	166	11	ethical	ethical	ADJ
dti-1424	166	12	and	and	CCONJ
dti-1424	166	13	legal	legal	ADJ
dti-1424	166	14	obligations	obligation	NOUN
dti-1424	166	15	including	include	VERB
dti-1424	166	16	(	(	PUNCT
dti-1424	166	17	but	but	CCONJ
dti-1424	166	18	not	not	PART
dti-1424	166	19	limited	limit	VERB
dti-1424	166	20	to	to	ADP
dti-1424	166	21	)	)	PUNCT
dti-1424	166	22	use	use	NOUN
dti-1424	166	23	of	of	ADP
dti-1424	166	24	any	any	DET
dti-1424	166	25	copyrighted	copyright	VERB
dti-1424	166	26	material	material	NOUN
dti-1424	166	27	,	,	PUNCT
dti-1424	166	28	compliance	compliance	NOUN
dti-1424	166	29	with	with	ADP
dti-1424	166	30	icmje	icmje	NOUN
dti-1424	166	31	authorship	authorship	NOUN
dti-1424	166	32	and	and	CCONJ
dti-1424	166	33	competing	compete	VERB
dti-1424	166	34	interests	interest	NOUN
dti-1424	166	35	disclosure	disclosure	NOUN
dti-1424	166	36	guidelines	guideline	NOUN
dti-1424	166	37	.	.	PUNCT
dti-1424	167	1	http://www.la-press.com/drug-target-insights-journal-j23	http://www.la-press.com/drug-target-insights-journal-j23	PROPN
dti-1424	167	2	http://www.la-press.com	http://www.la-press.com	X
dti-1424	168	1	mailto:francesconappi@gmail.com	mailto:francesconappi@gmail.com	PROPN
dti-1424	168	2	mailto:a.rainer@unicampus.it	mailto:a.rainer@unicampus.it	VERB
dti-1424	168	3	http://didattica.unicampus.it/didattica/guide/paginadocente.do;jsessionid=bb5df6e681779e9a0d9ee809d4665e1a.jvm1a?docente_id=325	http://didattica.unicampus.it/didattica/guide/paginadocente.do;jsessionid=bb5df6e681779e9a0d9ee809d4665e1a.jvm1a?docente_id=325	PROPN
dti-1424	168	4	http://didattica.unicampus.it/didattica/guide/paginadocente.do;jsessionid=bb5df6e681779e9a0d9ee809d4665e1a.jvm1a?docente_id=325	http://didattica.unicampus.it/didattica/guide/paginadocente.do;jsessionid=bb5df6e681779e9a0d9ee809d4665e1a.jvm1a?docente_id=325	PROPN
dti-1424	168	5	http://didattica.unicampus.it/didattica/guide/paginadocente.do;jsessionid=bb5df6e681779e9a0d9ee809d4665e1a.jvm1a?docente_id=325	http://didattica.unicampus.it/didattica/guide/paginadocente.do;jsessionid=bb5df6e681779e9a0d9ee809d4665e1a.jvm1a?docente_id=325	PROPN
dti-1424	168	6	mailto:mddvb@bristol.ac.uk	mailto:mddvb@bristol.ac.uk	PROPN
dti-1424	168	7	http://www.bris.ac.uk/clinical-sciences/people/182709/index.html	http://www.bris.ac.uk/clinical-sciences/people/182709/index.html	PROPN
dti-1424	168	8	http://www.bris.ac.uk/clinical-sciences/people/182709/index.html	http://www.bris.ac.uk/clinical-sciences/people/182709/index.html	PROPN
dti-1424	168	9	http://dx.doi.org/10.4137/dti.s41240	http://dx.doi.org/10.4137/dti.s41240	X
dti-1424	168	10	http://creativecommons.org/licenses/by-nc/3.0/	http://creativecommons.org/licenses/by-nc/3.0/	PROPN
dti-1424	168	11	http://creativecommons.org/licenses/by-nc/3.0/	http://creativecommons.org/licenses/by-nc/3.0/	PROPN
dti-1424	168	12	mailto:cristianospadaccio@gmail.com	mailto:cristianospadaccio@gmail.com	X