id	sid	tid	token	lemma	pos
dti-1548	1	1	dti	dti	PROPN
dti-1548	1	2	©	©	PROPN
dti-1548	1	3	2020	2020	NUM
dti-1548	1	4	the	the	DET
dti-1548	1	5	authors	author	NOUN
dti-1548	1	6	.	.	PUNCT
dti-1548	2	1	this	this	DET
dti-1548	2	2	article	article	NOUN
dti-1548	2	3	is	be	AUX
dti-1548	2	4	published	publish	VERB
dti-1548	2	5	by	by	ADP
dti-1548	2	6	aboutscience	aboutscience	NOUN
dti-1548	2	7	and	and	CCONJ
dti-1548	2	8	licensed	license	VERB
dti-1548	2	9	under	under	ADP
dti-1548	2	10	creative	creative	ADJ
dti-1548	2	11	commons	common	NOUN
dti-1548	2	12	attribution	attribution	NOUN
dti-1548	2	13	-	-	PUNCT
dti-1548	2	14	noncommercial	noncommercial	ADJ
dti-1548	2	15	4.0	4.0	NUM
dti-1548	2	16	international	international	NOUN
dti-1548	2	17	(	(	PUNCT
dti-1548	2	18	cc	cc	NOUN
dti-1548	2	19	by	by	ADP
dti-1548	2	20	-	-	PUNCT
dti-1548	2	21	nc	nc	PROPN
dti-1548	2	22	4.0	4.0	NUM
dti-1548	2	23	)	)	PUNCT
dti-1548	2	24	.	.	PUNCT
dti-1548	3	1	any	any	DET
dti-1548	3	2	commercial	commercial	ADJ
dti-1548	3	3	use	use	NOUN
dti-1548	3	4	is	be	AUX
dti-1548	3	5	not	not	PART
dti-1548	3	6	permitted	permit	VERB
dti-1548	3	7	and	and	CCONJ
dti-1548	3	8	is	be	AUX
dti-1548	3	9	subject	subject	ADJ
dti-1548	3	10	to	to	ADP
dti-1548	3	11	publisher	publisher	NOUN
dti-1548	3	12	’s	’s	PART
dti-1548	3	13	permissions	permission	NOUN
dti-1548	3	14	.	.	PUNCT
dti-1548	4	1	full	full	ADJ
dti-1548	4	2	information	information	NOUN
dti-1548	4	3	is	be	AUX
dti-1548	4	4	available	available	ADJ
dti-1548	4	5	at	at	ADP
dti-1548	4	6	www.aboutscience.eu	www.aboutscience.eu	PROPN
dti-1548	4	7	issn	issn	PROPN
dti-1548	4	8	1177	1177	NUM
dti-1548	4	9	-	-	SYM
dti-1548	4	10	3928	3928	NUM
dti-1548	4	11	drug	drug	NOUN
dti-1548	4	12	target	target	NOUN
dti-1548	4	13	insights	insight	NOUN
dti-1548	4	14	2020	2020	NUM
dti-1548	4	15	;	;	PUNCT
dti-1548	4	16	14	14	NUM
dti-1548	4	17	:	:	SYM
dti-1548	4	18	1	1	NUM
dti-1548	4	19	-	-	SYM
dti-1548	4	20	11	11	NUM
dti-1548	4	21	original	original	ADJ
dti-1548	4	22	research	research	NOUN
dti-1548	4	23	article	article	NOUN
dti-1548	4	24	doi	doi	NOUN
dti-1548	4	25	:	:	PUNCT
dti-1548	4	26	10.33393	10.33393	NUM
dti-1548	4	27	/	/	SYM
dti-1548	4	28	dti.2020.1548	dti.2020.1548	NOUN
dti-1548	4	29	identification	identification	NOUN
dti-1548	4	30	of	of	ADP
dti-1548	4	31	the	the	DET
dti-1548	4	32	possible	possible	ADJ
dti-1548	4	33	therapeutic	therapeutic	ADJ
dti-1548	4	34	targets	target	NOUN
dti-1548	4	35	in	in	ADP
dti-1548	4	36	the	the	DET
dti-1548	4	37	insulin	insulin	NOUN
dti-1548	4	38	-	-	PUNCT
dti-1548	4	39	like	like	ADJ
dti-1548	4	40	growth	growth	NOUN
dti-1548	4	41	factor	factor	NOUN
dti-1548	4	42	1	1	NUM
dti-1548	4	43	receptor	receptor	NOUN
dti-1548	4	44	pathway	pathway	NOUN
dti-1548	4	45	in	in	ADP
dti-1548	4	46	a	a	DET
dti-1548	4	47	cohort	cohort	NOUN
dti-1548	4	48	of	of	ADP
dti-1548	4	49	egyptian	egyptian	ADJ
dti-1548	4	50	hepatocellular	hepatocellular	ADJ
dti-1548	4	51	carcinoma	carcinoma	NOUN
dti-1548	4	52	complicating	complicate	VERB
dti-1548	4	53	chronic	chronic	ADJ
dti-1548	4	54	hepatitis	hepatitis	NOUN
dti-1548	4	55	c	c	PROPN
dti-1548	4	56	type	type	NOUN
dti-1548	4	57	4	4	NUM
dti-1548	4	58	nada	nada	PROPN
dti-1548	4	59	m.k	m.k	PROPN
dti-1548	4	60	.	.	PROPN
dti-1548	4	61	mabrouk1	mabrouk1	PROPN
dti-1548	4	62	,	,	PUNCT
dti-1548	5	1	dalal	dalal	PROPN
dti-1548	5	2	m.	m.	PROPN
dti-1548	5	3	elkaffash2,3	elkaffash2,3	PROPN
dti-1548	5	4	,	,	PUNCT
dti-1548	5	5	mona	mona	PROPN
dti-1548	5	6	abdel	abdel	PROPN
dti-1548	5	7	-	-	PUNCT
dti-1548	5	8	hadi1	hadi1	PROPN
dti-1548	5	9	,	,	PUNCT
dti-1548	5	10	salah	salah	PROPN
dti-1548	5	11	-	-	PUNCT
dti-1548	5	12	eldin	eldin	PROPN
dti-1548	5	13	abdelmoneim4	abdelmoneim4	PROPN
dti-1548	5	14	,	,	PUNCT
dti-1548	5	15	sameh	sameh	NOUN
dti-1548	5	16	saad	saad	PROPN
dti-1548	5	17	eldeen3	eldeen3	PROPN
dti-1548	5	18	,	,	PUNCT
dti-1548	5	19	gihan	gihan	PROPN
dti-1548	5	20	gewaifel6	gewaifel6	PROPN
dti-1548	5	21	,	,	PUNCT
dti-1548	5	22	khaled	khaled	PROPN
dti-1548	5	23	a.	a.	PROPN
dti-1548	5	24	elella5	elella5	PROPN
dti-1548	5	25	,	,	PUNCT
dti-1548	5	26	maher	maher	PROPN
dti-1548	5	27	osman5	osman5	PROPN
dti-1548	5	28	,	,	PUNCT
dti-1548	5	29	nahed	nahe	VERB
dti-1548	5	30	baddour1	baddour1	PROPN
dti-1548	5	31	1	1	NUM
dti-1548	5	32	department	department	NOUN
dti-1548	5	33	of	of	ADP
dti-1548	5	34	pathology	pathology	PROPN
dti-1548	5	35	,	,	PUNCT
dti-1548	5	36	university	university	PROPN
dti-1548	5	37	of	of	ADP
dti-1548	5	38	alexandria	alexandria	PROPN
dti-1548	5	39	,	,	PUNCT
dti-1548	5	40	alexandria	alexandria	PROPN
dti-1548	5	41	egypt	egypt	PROPN
dti-1548	5	42	2	2	NUM
dti-1548	5	43	alexandria	alexandria	PROPN
dti-1548	5	44	regional	regional	ADJ
dti-1548	5	45	center	center	NOUN
dti-1548	5	46	for	for	ADP
dti-1548	5	47	women	woman	NOUN
dti-1548	5	48	’s	’s	PART
dti-1548	5	49	health	health	NOUN
dti-1548	5	50	and	and	CCONJ
dti-1548	5	51	development	development	NOUN
dti-1548	5	52	,	,	PUNCT
dti-1548	5	53	alexandria	alexandria	PROPN
dti-1548	5	54	egypt	egypt	PROPN
dti-1548	5	55	3	3	NUM
dti-1548	5	56	department	department	NOUN
dti-1548	5	57	of	of	ADP
dti-1548	5	58	clinical	clinical	ADJ
dti-1548	5	59	and	and	CCONJ
dti-1548	5	60	chemical	chemical	ADJ
dti-1548	5	61	pathology	pathology	NOUN
dti-1548	5	62	,	,	PUNCT
dti-1548	5	63	university	university	PROPN
dti-1548	5	64	of	of	ADP
dti-1548	5	65	alexandria	alexandria	PROPN
dti-1548	5	66	,	,	PUNCT
dti-1548	5	67	alexandria	alexandria	PROPN
dti-1548	5	68	egypt	egypt	PROPN
dti-1548	5	69	4	4	NUM
dti-1548	5	70	department	department	NOUN
dti-1548	5	71	of	of	ADP
dti-1548	5	72	clinical	clinical	ADJ
dti-1548	5	73	oncology	oncology	NOUN
dti-1548	5	74	and	and	CCONJ
dti-1548	5	75	nuclear	nuclear	ADJ
dti-1548	5	76	medicine	medicine	NOUN
dti-1548	5	77	,	,	PUNCT
dti-1548	5	78	university	university	PROPN
dti-1548	5	79	of	of	ADP
dti-1548	5	80	alexandria	alexandria	PROPN
dti-1548	5	81	,	,	PUNCT
dti-1548	5	82	alexandria	alexandria	PROPN
dti-1548	5	83	egypt	egypt	PROPN
dti-1548	5	84	5	5	NUM
dti-1548	5	85	department	department	PROPN
dti-1548	5	86	of	of	ADP
dti-1548	5	87	general	general	ADJ
dti-1548	5	88	surgery	surgery	NOUN
dti-1548	5	89	,	,	PUNCT
dti-1548	5	90	university	university	PROPN
dti-1548	5	91	of	of	ADP
dti-1548	5	92	alexandria	alexandria	PROPN
dti-1548	5	93	,	,	PUNCT
dti-1548	5	94	alexandria	alexandria	PROPN
dti-1548	5	95	egypt	egypt	PROPN
dti-1548	5	96	6	6	NUM
dti-1548	5	97	public	public	ADJ
dti-1548	5	98	health	health	NOUN
dti-1548	5	99	department	department	NOUN
dti-1548	5	100	,	,	PUNCT
dti-1548	5	101	faculty	faculty	NOUN
dti-1548	5	102	of	of	ADP
dti-1548	5	103	medicine	medicine	NOUN
dti-1548	5	104	,	,	PUNCT
dti-1548	5	105	university	university	PROPN
dti-1548	5	106	of	of	ADP
dti-1548	5	107	alexandria	alexandria	PROPN
dti-1548	5	108	,	,	PUNCT
dti-1548	5	109	alexandria	alexandria	PROPN
dti-1548	5	110	egypt	egypt	PROPN
dti-1548	5	111	abstract	abstract	ADJ
dti-1548	5	112	background	background	NOUN
dti-1548	5	113	:	:	PUNCT
dti-1548	5	114	molecular	molecular	ADJ
dti-1548	5	115	targeted	target	VERB
dti-1548	5	116	drugs	drug	NOUN
dti-1548	5	117	are	be	AUX
dti-1548	5	118	the	the	DET
dti-1548	5	119	first	first	ADJ
dti-1548	5	120	line	line	NOUN
dti-1548	5	121	of	of	ADP
dti-1548	5	122	treatment	treatment	NOUN
dti-1548	5	123	of	of	ADP
dti-1548	5	124	advanced	advanced	ADJ
dti-1548	5	125	hepatocellular	hepatocellular	ADJ
dti-1548	5	126	carcinoma	carcinoma	NOUN
dti-1548	5	127	(	(	PUNCT
dti-1548	5	128	hcc	hcc	PROPN
dti-1548	5	129	)	)	PUNCT
dti-1548	5	130	due	due	ADP
dti-1548	5	131	to	to	ADP
dti-1548	5	132	its	its	PRON
dti-1548	5	133	chemoand	chemoand	ADJ
dti-1548	5	134	radioresistant	radioresistant	ADJ
dti-1548	5	135	nature	nature	NOUN
dti-1548	5	136	.	.	PUNCT
dti-1548	6	1	hcc	hcc	PROPN
dti-1548	6	2	has	have	VERB
dti-1548	6	3	several	several	ADJ
dti-1548	6	4	well	well	ADV
dti-1548	6	5	-	-	PUNCT
dti-1548	6	6	documented	document	VERB
dti-1548	6	7	etiologic	etiologic	ADJ
dti-1548	6	8	factors	factor	NOUN
dti-1548	6	9	that	that	PRON
dti-1548	6	10	drive	drive	VERB
dti-1548	6	11	hepatocarcinogenesis	hepatocarcinogenesis	NOUN
dti-1548	6	12	through	through	ADP
dti-1548	6	13	different	different	ADJ
dti-1548	6	14	molecular	molecular	ADJ
dti-1548	6	15	pathways	pathway	NOUN
dti-1548	6	16	.	.	PUNCT
dti-1548	7	1	currently	currently	ADV
dti-1548	7	2	,	,	PUNCT
dti-1548	7	3	hepatitis	hepatitis	PROPN
dti-1548	7	4	c	c	PROPN
dti-1548	7	5	virus	virus	NOUN
dti-1548	7	6	(	(	PUNCT
dti-1548	7	7	hcv	hcv	PROPN
dti-1548	7	8	)	)	PUNCT
dti-1548	7	9	is	be	AUX
dti-1548	7	10	a	a	DET
dti-1548	7	11	leading	lead	VERB
dti-1548	7	12	cause	cause	NOUN
dti-1548	7	13	of	of	ADP
dti-1548	7	14	hcc	hcc	PROPN
dti-1548	7	15	.	.	PUNCT
dti-1548	8	1	therefore	therefore	ADV
dti-1548	8	2	,	,	PUNCT
dti-1548	8	3	we	we	PRON
dti-1548	8	4	included	include	VERB
dti-1548	8	5	a	a	DET
dti-1548	8	6	unified	unified	ADJ
dti-1548	8	7	cohort	cohort	NOUN
dti-1548	8	8	of	of	ADP
dti-1548	8	9	hcv	hcv	NOUN
dti-1548	8	10	genotype	genotype	NOUN
dti-1548	8	11	4	4	NUM
dti-1548	8	12	-	-	PUNCT
dti-1548	8	13	related	relate	VERB
dti-1548	8	14	hccs	hccs	NOUN
dti-1548	8	15	to	to	PART
dti-1548	8	16	study	study	VERB
dti-1548	8	17	the	the	DET
dti-1548	8	18	expression	expression	NOUN
dti-1548	8	19	levels	level	NOUN
dti-1548	8	20	of	of	ADP
dti-1548	8	21	genes	gene	NOUN
dti-1548	8	22	involved	involve	VERB
dti-1548	8	23	in	in	ADP
dti-1548	8	24	the	the	DET
dti-1548	8	25	insulin	insulin	NOUN
dti-1548	8	26	-	-	PUNCT
dti-1548	8	27	like	like	ADJ
dti-1548	8	28	growth	growth	NOUN
dti-1548	8	29	factor	factor	NOUN
dti-1548	8	30	1	1	NUM
dti-1548	8	31	receptor	receptor	NOUN
dti-1548	8	32	(	(	PUNCT
dti-1548	8	33	igf1r	igf1r	ADJ
dti-1548	8	34	)	)	PUNCT
dti-1548	8	35	pathway	pathway	NOUN
dti-1548	8	36	,	,	PUNCT
dti-1548	8	37	which	which	PRON
dti-1548	8	38	is	be	AUX
dti-1548	8	39	known	know	VERB
dti-1548	8	40	to	to	PART
dti-1548	8	41	be	be	AUX
dti-1548	8	42	involved	involve	VERB
dti-1548	8	43	in	in	ADP
dti-1548	8	44	all	all	DET
dti-1548	8	45	aspects	aspect	NOUN
dti-1548	8	46	of	of	ADP
dti-1548	8	47	cancer	cancer	NOUN
dti-1548	8	48	growth	growth	NOUN
dti-1548	8	49	and	and	CCONJ
dti-1548	8	50	progression	progression	NOUN
dti-1548	8	51	.	.	PUNCT
dti-1548	9	1	aim	aim	NOUN
dti-1548	9	2	:	:	PUNCT
dti-1548	9	3	determine	determine	VERB
dti-1548	9	4	the	the	DET
dti-1548	9	5	gene	gene	NOUN
dti-1548	9	6	expression	expression	NOUN
dti-1548	9	7	patterns	pattern	NOUN
dti-1548	9	8	of	of	ADP
dti-1548	9	9	igf1r	igf1r	PRON
dti-1548	9	10	pathway	pathway	NOUN
dti-1548	9	11	genes	gene	NOUN
dti-1548	9	12	in	in	ADP
dti-1548	9	13	a	a	DET
dti-1548	9	14	cohort	cohort	NOUN
dti-1548	9	15	of	of	ADP
dti-1548	9	16	egyptian	egyptian	ADJ
dti-1548	9	17	hcv	hcv	PROPN
dti-1548	9	18	-	-	PUNCT
dti-1548	9	19	related	relate	VERB
dti-1548	9	20	hccs	hccs	NOUN
dti-1548	9	21	.	.	PUNCT
dti-1548	10	1	correlate	correlate	VERB
dti-1548	10	2	them	they	PRON
dti-1548	10	3	with	with	ADP
dti-1548	10	4	different	different	ADJ
dti-1548	10	5	patient	patient	NOUN
dti-1548	10	6	/	/	SYM
dti-1548	10	7	tumor	tumor	NOUN
dti-1548	10	8	characteristics	characteristic	NOUN
dti-1548	10	9	.	.	PUNCT
dti-1548	11	1	determine	determine	VERB
dti-1548	11	2	the	the	DET
dti-1548	11	3	activity	activity	NOUN
dti-1548	11	4	status	status	NOUN
dti-1548	11	5	of	of	ADP
dti-1548	11	6	involved	involved	ADJ
dti-1548	11	7	pathways	pathway	NOUN
dti-1548	11	8	.	.	PUNCT
dti-1548	12	1	methods	method	NOUN
dti-1548	12	2	:	:	PUNCT
dti-1548	12	3	total	total	ADJ
dti-1548	12	4	ribonucleic	ribonucleic	ADJ
dti-1548	12	5	acid	acid	NOUN
dti-1548	12	6	(	(	PUNCT
dti-1548	12	7	rna	rna	PROPN
dti-1548	12	8	)	)	PUNCT
dti-1548	12	9	was	be	AUX
dti-1548	12	10	extracted	extract	VERB
dti-1548	12	11	from	from	ADP
dti-1548	12	12	32	32	NUM
dti-1548	12	13	formalin	formalin	NOUN
dti-1548	12	14	-	-	PUNCT
dti-1548	12	15	fixed	fix	VERB
dti-1548	12	16	paraffin	paraffin	NOUN
dti-1548	12	17	-	-	PUNCT
dti-1548	12	18	embedded	embed	VERB
dti-1548	12	19	tissues	tissue	NOUN
dti-1548	12	20	of	of	ADP
dti-1548	12	21	human	human	ADJ
dti-1548	12	22	hcv	hcv	PROPN
dti-1548	12	23	-	-	PUNCT
dti-1548	12	24	related	relate	VERB
dti-1548	12	25	hccs	hccs	NOUN
dti-1548	12	26	and	and	CCONJ
dti-1548	12	27	6	6	NUM
dti-1548	12	28	healthy	healthy	ADJ
dti-1548	12	29	liver	liver	NOUN
dti-1548	12	30	donors	donor	NOUN
dti-1548	12	31	as	as	ADP
dti-1548	12	32	controls	control	NOUN
dti-1548	12	33	.	.	PUNCT
dti-1548	13	1	quantitative	quantitative	ADJ
dti-1548	13	2	reverse	reverse	ADJ
dti-1548	13	3	transcription	transcription	NOUN
dti-1548	13	4	polymerase	polymerase	NOUN
dti-1548	13	5	chain	chain	NOUN
dti-1548	13	6	reaction	reaction	NOUN
dti-1548	13	7	(	(	PUNCT
dti-1548	13	8	qrt	qrt	NOUN
dti-1548	13	9	-	-	PUNCT
dti-1548	13	10	pcr	pcr	NOUN
dti-1548	13	11	)	)	PUNCT
dti-1548	13	12	using	use	VERB
dti-1548	13	13	rt2	rt2	PROPN
dti-1548	13	14	profiler	profiler	NOUN
dti-1548	13	15	pcr	pcr	ADJ
dti-1548	13	16	array	array	NOUN
dti-1548	13	17	for	for	ADP
dti-1548	13	18	human	human	ADJ
dti-1548	13	19	insulin	insulin	NOUN
dti-1548	13	20	signaling	signal	VERB
dti-1548	13	21	pathway	pathway	NOUN
dti-1548	13	22	was	be	AUX
dti-1548	13	23	done	do	VERB
dti-1548	13	24	to	to	PART
dti-1548	13	25	determine	determine	VERB
dti-1548	13	26	significantly	significantly	ADV
dti-1548	13	27	upand	upand	PROPN
dti-1548	13	28	downregulated	downregulate	VERB
dti-1548	13	29	genes	gene	NOUN
dti-1548	13	30	with	with	ADP
dti-1548	13	31	identification	identification	NOUN
dti-1548	13	32	of	of	ADP
dti-1548	13	33	most	most	ADV
dti-1548	13	34	frequently	frequently	ADV
dti-1548	13	35	coregulated	coregulate	VERB
dti-1548	13	36	genes	gene	NOUN
dti-1548	13	37	,	,	PUNCT
dti-1548	13	38	followed	follow	VERB
dti-1548	13	39	by	by	ADP
dti-1548	13	40	correlation	correlation	NOUN
dti-1548	13	41	of	of	ADP
dti-1548	13	42	gene	gene	NOUN
dti-1548	13	43	expression	expression	NOUN
dti-1548	13	44	with	with	ADP
dti-1548	13	45	different	different	ADJ
dti-1548	13	46	patient	patient	NOUN
dti-1548	13	47	/	/	SYM
dti-1548	13	48	tumor	tumor	NOUN
dti-1548	13	49	characteristics	characteristic	NOUN
dti-1548	13	50	.	.	PUNCT
dti-1548	14	1	finally	finally	ADV
dti-1548	14	2	,	,	PUNCT
dti-1548	14	3	canonical	canonical	ADJ
dti-1548	14	4	pathway	pathway	NOUN
dti-1548	14	5	analysis	analysis	NOUN
dti-1548	14	6	was	be	AUX
dti-1548	14	7	performed	perform	VERB
dti-1548	14	8	using	use	VERB
dti-1548	14	9	the	the	DET
dti-1548	14	10	ingenuity	ingenuity	NOUN
dti-1548	14	11	pathway	pathway	NOUN
dti-1548	14	12	analysis	analysis	NOUN
dti-1548	14	13	software	software	NOUN
dti-1548	14	14	.	.	PUNCT
dti-1548	15	1	results	result	NOUN
dti-1548	15	2	:	:	PUNCT
dti-1548	15	3	six	six	NUM
dti-1548	15	4	genes	gene	NOUN
dti-1548	15	5	–	–	PUNCT
dti-1548	15	6	aebp1	aebp1	NOUN
dti-1548	15	7	,	,	PUNCT
dti-1548	15	8	akt2	akt2	PROPN
dti-1548	15	9	,	,	PUNCT
dti-1548	15	10	c	c	NOUN
dti-1548	15	11	-	-	PUNCT
dti-1548	15	12	fos	fos	NOUN
dti-1548	15	13	,	,	PUNCT
dti-1548	15	14	pik3r1	pik3r1	ADJ
dti-1548	15	15	,	,	PUNCT
dti-1548	15	16	prkci	prkci	ADJ
dti-1548	15	17	,	,	PUNCT
dti-1548	15	18	shc1	shc1	PROPN
dti-1548	15	19	–	–	PUNCT
dti-1548	15	20	were	be	AUX
dti-1548	15	21	significantly	significantly	ADV
dti-1548	15	22	overexpressed	overexpresse	VERB
dti-1548	15	23	.	.	PUNCT
dti-1548	16	1	thirteen	thirteen	NUM
dti-1548	16	2	genes	gene	NOUN
dti-1548	16	3	–	–	PUNCT
dti-1548	16	4	adrb3	adrb3	ADJ
dti-1548	16	5	,	,	PUNCT
dti-1548	16	6	cebpa	cebpa	NOUN
dti-1548	16	7	,	,	PUNCT
dti-1548	16	8	dusp14	dusp14	NOUN
dti-1548	16	9	,	,	PUNCT
dti-1548	16	10	ercc1	ercc1	PROPN
dti-1548	16	11	,	,	PUNCT
dti-1548	16	12	frs3	frs3	PROPN
dti-1548	16	13	,	,	PUNCT
dti-1548	16	14	igf2	igf2	PROPN
dti-1548	16	15	,	,	PUNCT
dti-1548	16	16	ins	ins	PROPN
dti-1548	16	17	,	,	PUNCT
dti-1548	16	18	irs1	irs1	PROPN
dti-1548	16	19	,	,	PUNCT
dti-1548	16	20	jun	jun	PROPN
dti-1548	16	21	,	,	PUNCT
dti-1548	16	22	mtor	mtor	PROPN
dti-1548	16	23	,	,	PUNCT
dti-1548	16	24	pik3r2	pik3r2	ADV
dti-1548	16	25	,	,	PUNCT
dti-1548	16	26	ppp1ca	ppp1ca	NOUN
dti-1548	16	27	,	,	PUNCT
dti-1548	16	28	rps6ka1	rps6ka1	PROPN
dti-1548	16	29	–	–	PUNCT
dti-1548	16	30	were	be	AUX
dti-1548	16	31	significantly	significantly	ADV
dti-1548	16	32	underexpressed	underexpressed	ADJ
dti-1548	16	33	.	.	PUNCT
dti-1548	17	1	several	several	ADJ
dti-1548	17	2	differentially	differentially	ADV
dti-1548	17	3	expressed	express	VERB
dti-1548	17	4	genes	gene	NOUN
dti-1548	17	5	were	be	AUX
dti-1548	17	6	related	relate	VERB
dti-1548	17	7	to	to	ADP
dti-1548	17	8	different	different	ADJ
dti-1548	17	9	tumor	tumor	NOUN
dti-1548	17	10	/	/	SYM
dti-1548	17	11	patient	patient	NOUN
dti-1548	17	12	characteristics	characteristic	NOUN
dti-1548	17	13	.	.	PUNCT
dti-1548	18	1	nitric	nitric	ADJ
dti-1548	18	2	oxide	oxide	NOUN
dti-1548	18	3	and	and	CCONJ
dti-1548	18	4	reactive	reactive	ADJ
dti-1548	18	5	oxygen	oxygen	NOUN
dti-1548	18	6	species	specie	NOUN
dti-1548	18	7	production	production	NOUN
dti-1548	18	8	pathway	pathway	NOUN
dti-1548	18	9	was	be	AUX
dti-1548	18	10	significantly	significantly	ADV
dti-1548	18	11	activated	activate	VERB
dti-1548	18	12	in	in	ADP
dti-1548	18	13	the	the	DET
dti-1548	18	14	present	present	ADJ
dti-1548	18	15	cohort	cohort	NOUN
dti-1548	18	16	,	,	PUNCT
dti-1548	18	17	while	while	SCONJ
dti-1548	18	18	the	the	DET
dti-1548	18	19	growth	growth	NOUN
dti-1548	18	20	hormone	hormone	NOUN
dti-1548	18	21	signaling	signal	VERB
dti-1548	18	22	pathway	pathway	NOUN
dti-1548	18	23	was	be	AUX
dti-1548	18	24	inactive	inactive	ADJ
dti-1548	18	25	.	.	PUNCT
dti-1548	19	1	conclusions	conclusion	NOUN
dti-1548	19	2	:	:	PUNCT
dti-1548	19	3	the	the	DET
dti-1548	19	4	gene	gene	NOUN
dti-1548	19	5	expression	expression	NOUN
dti-1548	19	6	patterns	pattern	NOUN
dti-1548	19	7	identified	identify	VERB
dti-1548	19	8	in	in	ADP
dti-1548	19	9	this	this	DET
dti-1548	19	10	study	study	NOUN
dti-1548	19	11	may	may	AUX
dti-1548	19	12	serve	serve	VERB
dti-1548	19	13	as	as	ADP
dti-1548	19	14	possible	possible	ADJ
dti-1548	19	15	therapeutic	therapeutic	ADJ
dti-1548	19	16	targets	target	NOUN
dti-1548	19	17	in	in	ADP
dti-1548	19	18	hcv	hcv	NOUN
dti-1548	19	19	-	-	PUNCT
dti-1548	19	20	related	relate	VERB
dti-1548	19	21	hccs	hccs	NOUN
dti-1548	19	22	.	.	PUNCT
dti-1548	20	1	the	the	DET
dti-1548	20	2	most	most	ADV
dti-1548	20	3	frequently	frequently	ADV
dti-1548	20	4	coregulated	coregulate	VERB
dti-1548	20	5	genes	gene	NOUN
dti-1548	20	6	may	may	AUX
dti-1548	20	7	serve	serve	VERB
dti-1548	20	8	to	to	PART
dti-1548	20	9	guide	guide	VERB
dti-1548	20	10	combined	combine	VERB
dti-1548	20	11	molecular	molecular	ADJ
dti-1548	20	12	targeted	target	VERB
dti-1548	20	13	therapies	therapy	NOUN
dti-1548	20	14	.	.	PUNCT
dti-1548	21	1	the	the	DET
dti-1548	21	2	igf1r	igf1r	PROPN
dti-1548	21	3	pathway	pathway	NOUN
dti-1548	21	4	showed	show	VERB
dti-1548	21	5	evidence	evidence	NOUN
dti-1548	21	6	of	of	ADP
dti-1548	21	7	inactivity	inactivity	NOUN
dti-1548	21	8	in	in	ADP
dti-1548	21	9	the	the	DET
dti-1548	21	10	present	present	ADJ
dti-1548	21	11	cohort	cohort	NOUN
dti-1548	21	12	of	of	ADP
dti-1548	21	13	hcv	hcv	NOUN
dti-1548	21	14	-	-	PUNCT
dti-1548	21	15	related	relate	VERB
dti-1548	21	16	hccs	hccs	NOUN
dti-1548	21	17	,	,	PUNCT
dti-1548	21	18	so	so	ADV
dti-1548	21	19	targeting	target	VERB
dti-1548	21	20	this	this	DET
dti-1548	21	21	pathway	pathway	NOUN
dti-1548	21	22	in	in	ADP
dti-1548	21	23	therapy	therapy	NOUN
dti-1548	21	24	may	may	AUX
dti-1548	21	25	not	not	PART
dti-1548	21	26	be	be	AUX
dti-1548	21	27	effective	effective	ADJ
dti-1548	21	28	.	.	PUNCT
dti-1548	22	1	keywords	keyword	NOUN
dti-1548	22	2	:	:	PUNCT
dti-1548	22	3	gene	gene	NOUN
dti-1548	22	4	expression	expression	NOUN
dti-1548	22	5	,	,	PUNCT
dti-1548	22	6	hepatitis	hepatitis	PROPN
dti-1548	22	7	c	c	PROPN
dti-1548	22	8	virus	virus	NOUN
dti-1548	22	9	,	,	PUNCT
dti-1548	22	10	hepatocellular	hepatocellular	ADJ
dti-1548	22	11	carcinoma	carcinoma	NOUN
dti-1548	22	12	,	,	PUNCT
dti-1548	22	13	molecular	molecular	ADJ
dti-1548	22	14	therapeutic	therapeutic	ADJ
dti-1548	22	15	targets	target	NOUN
dti-1548	22	16	received	receive	VERB
dti-1548	22	17	:	:	PUNCT
dti-1548	22	18	january	january	PROPN
dti-1548	22	19	8	8	NUM
dti-1548	22	20	,	,	PUNCT
dti-1548	22	21	2020	2020	NUM
dti-1548	22	22	accepted	accept	VERB
dti-1548	22	23	:	:	PUNCT
dti-1548	22	24	january	january	PROPN
dti-1548	22	25	20	20	NUM
dti-1548	22	26	,	,	PUNCT
dti-1548	22	27	2020	2020	NUM
dti-1548	22	28	published	publish	VERB
dti-1548	22	29	online	online	ADV
dti-1548	22	30	:	:	PUNCT
dti-1548	22	31	april	april	PROPN
dti-1548	22	32	8	8	NUM
dti-1548	22	33	,	,	PUNCT
dti-1548	22	34	2020	2020	NUM
dti-1548	22	35	corresponding	correspond	VERB
dti-1548	22	36	author	author	NOUN
dti-1548	22	37	:	:	PUNCT
dti-1548	22	38	nada	nada	PROPN
dti-1548	22	39	m.k	m.k	PROPN
dti-1548	22	40	.	.	PROPN
dti-1548	22	41	mabrouk	mabrouk	PROPN
dti-1548	22	42	department	department	PROPN
dti-1548	22	43	of	of	ADP
dti-1548	22	44	pathology	pathology	PROPN
dti-1548	22	45	university	university	PROPN
dti-1548	22	46	of	of	ADP
dti-1548	22	47	alexandria	alexandria	PROPN
dti-1548	22	48	alexandria	alexandria	PROPN
dti-1548	22	49	,	,	PUNCT
dti-1548	22	50	egypt	egypt	PROPN
dti-1548	22	51	nada_mabrouk@hotmail.com	nada_mabrouk@hotmail.com	PROPN
dti-1548	22	52	,	,	PUNCT
dti-1548	22	53	nada.mabrouk@alexmed.edu.eg	nada.mabrouk@alexmed.edu.eg	ADV
dti-1548	22	54	introduction	introduction	NOUN
dti-1548	22	55	hepatocellular	hepatocellular	ADJ
dti-1548	22	56	carcinoma	carcinoma	NOUN
dti-1548	22	57	(	(	PUNCT
dti-1548	22	58	hcc	hcc	NOUN
dti-1548	22	59	)	)	PUNCT
dti-1548	22	60	has	have	AUX
dti-1548	22	61	become	become	VERB
dti-1548	22	62	the	the	DET
dti-1548	22	63	fifth	fifth	ADJ
dti-1548	22	64	most	most	ADV
dti-1548	22	65	common	common	ADJ
dti-1548	22	66	cancer	cancer	NOUN
dti-1548	22	67	in	in	ADP
dti-1548	22	68	men	man	NOUN
dti-1548	22	69	worldwide	worldwide	ADV
dti-1548	22	70	and	and	CCONJ
dti-1548	22	71	the	the	DET
dti-1548	22	72	ninth	ninth	ADJ
dti-1548	22	73	in	in	ADP
dti-1548	22	74	women	woman	NOUN
dti-1548	22	75	and	and	CCONJ
dti-1548	22	76	the	the	DET
dti-1548	22	77	third	third	ADJ
dti-1548	22	78	leading	lead	VERB
dti-1548	22	79	cause	cause	NOUN
dti-1548	22	80	of	of	ADP
dti-1548	22	81	cancer	cancer	NOUN
dti-1548	22	82	-	-	PUNCT
dti-1548	22	83	related	relate	VERB
dti-1548	22	84	deaths	death	NOUN
dti-1548	22	85	.	.	PUNCT
dti-1548	23	1	distinct	distinct	ADJ
dti-1548	23	2	geographical	geographical	ADJ
dti-1548	23	3	variations	variation	NOUN
dti-1548	23	4	in	in	ADP
dti-1548	23	5	the	the	DET
dti-1548	23	6	incidence	incidence	NOUN
dti-1548	23	7	exist	exist	VERB
dti-1548	23	8	.	.	PUNCT
dti-1548	24	1	in	in	ADP
dti-1548	24	2	egypt	egypt	PROPN
dti-1548	24	3	,	,	PUNCT
dti-1548	24	4	hcc	hcc	PROPN
dti-1548	24	5	has	have	VERB
dti-1548	24	6	the	the	DET
dti-1548	24	7	highest	high	ADJ
dti-1548	24	8	age	age	NOUN
dti-1548	24	9	-	-	PUNCT
dti-1548	24	10	standardized	standardize	VERB
dti-1548	24	11	incidence	incidence	NOUN
dti-1548	24	12	and	and	CCONJ
dti-1548	24	13	mortality	mortality	NOUN
dti-1548	24	14	rates	rate	NOUN
dti-1548	24	15	(	(	PUNCT
dti-1548	24	16	asr	asr	PROPN
dti-1548	24	17	)	)	PUNCT
dti-1548	24	18	from	from	ADP
dti-1548	24	19	cancer	cancer	NOUN
dti-1548	24	20	in	in	ADP
dti-1548	24	21	males	male	NOUN
dti-1548	24	22	and	and	CCONJ
dti-1548	24	23	ranks	rank	VERB
dti-1548	24	24	second	second	ADV
dti-1548	24	25	in	in	ADP
dti-1548	24	26	females	female	NOUN
dti-1548	24	27	(	(	PUNCT
dti-1548	24	28	1	1	NUM
dti-1548	24	29	)	)	PUNCT
dti-1548	24	30	.	.	PUNCT
dti-1548	25	1	most	most	ADJ
dti-1548	25	2	of	of	ADP
dti-1548	25	3	the	the	DET
dti-1548	25	4	burden	burden	NOUN
dti-1548	25	5	is	be	AUX
dti-1548	25	6	in	in	ADP
dti-1548	25	7	developing	develop	VERB
dti-1548	25	8	countries	country	NOUN
dti-1548	25	9	where	where	SCONJ
dti-1548	25	10	83	83	NUM
dti-1548	25	11	%	%	NOUN
dti-1548	25	12	of	of	ADP
dti-1548	25	13	cases	case	NOUN
dti-1548	25	14	(	(	PUNCT
dti-1548	25	15	and	and	CCONJ
dti-1548	25	16	deaths	death	NOUN
dti-1548	25	17	)	)	PUNCT
dti-1548	25	18	occur	occur	VERB
dti-1548	25	19	(	(	PUNCT
dti-1548	25	20	2	2	NUM
dti-1548	25	21	)	)	PUNCT
dti-1548	25	22	.	.	PUNCT
dti-1548	26	1	hcc	hcc	PROPN
dti-1548	26	2	has	have	VERB
dti-1548	26	3	several	several	ADJ
dti-1548	26	4	possible	possible	ADJ
dti-1548	26	5	therapeutic	therapeutic	ADJ
dti-1548	26	6	targets	target	NOUN
dti-1548	26	7	in	in	ADP
dti-1548	26	8	igf1r	igf1r	ADJ
dti-1548	26	9	pathway	pathway	NOUN
dti-1548	26	10	in	in	ADP
dti-1548	26	11	egyptian	egyptian	PROPN
dti-1548	26	12	hcv	hcv	X
dti-1548	26	13	related	relate	VERB
dti-1548	26	14	hcc2	hcc2	PROPN
dti-1548	26	15	©	©	PROPN
dti-1548	26	16	2020	2020	NUM
dti-1548	26	17	the	the	DET
dti-1548	26	18	authors	author	NOUN
dti-1548	26	19	.	.	PUNCT
dti-1548	27	1	published	publish	VERB
dti-1548	27	2	by	by	ADP
dti-1548	27	3	aboutscience	aboutscience	NOUN
dti-1548	27	4	well	well	ADV
dti-1548	27	5	-	-	PUNCT
dti-1548	27	6	documented	document	VERB
dti-1548	27	7	etiologic	etiologic	ADJ
dti-1548	27	8	factors	factor	NOUN
dti-1548	27	9	that	that	PRON
dti-1548	27	10	drive	drive	VERB
dti-1548	27	11	hepatocarcinogenesis	hepatocarcinogenesis	NOUN
dti-1548	27	12	through	through	ADP
dti-1548	27	13	different	different	ADJ
dti-1548	27	14	molecular	molecular	ADJ
dti-1548	27	15	pathways	pathway	NOUN
dti-1548	27	16	.	.	PUNCT
dti-1548	28	1	currently	currently	ADV
dti-1548	28	2	,	,	PUNCT
dti-1548	28	3	hepatitis	hepatitis	PROPN
dti-1548	28	4	c	c	PROPN
dti-1548	28	5	virus	virus	NOUN
dti-1548	28	6	(	(	PUNCT
dti-1548	28	7	hcv	hcv	PROPN
dti-1548	28	8	)	)	PUNCT
dti-1548	28	9	is	be	AUX
dti-1548	28	10	a	a	DET
dti-1548	28	11	leading	lead	VERB
dti-1548	28	12	cause	cause	NOUN
dti-1548	28	13	of	of	ADP
dti-1548	28	14	hcc	hcc	PROPN
dti-1548	28	15	.	.	PUNCT
dti-1548	29	1	the	the	DET
dti-1548	29	2	multiplicity	multiplicity	NOUN
dti-1548	29	3	of	of	ADP
dti-1548	29	4	etiologies	etiology	NOUN
dti-1548	29	5	of	of	ADP
dti-1548	29	6	hcc	hcc	PROPN
dti-1548	29	7	and	and	CCONJ
dti-1548	29	8	the	the	DET
dti-1548	29	9	existence	existence	NOUN
dti-1548	29	10	of	of	ADP
dti-1548	29	11	substantial	substantial	ADJ
dti-1548	29	12	molecular	molecular	ADJ
dti-1548	29	13	heterogeneity	heterogeneity	NOUN
dti-1548	29	14	might	might	AUX
dti-1548	29	15	limit	limit	VERB
dti-1548	29	16	the	the	DET
dti-1548	29	17	benefits	benefit	NOUN
dti-1548	29	18	of	of	ADP
dti-1548	29	19	targeted	target	VERB
dti-1548	29	20	approaches	approach	NOUN
dti-1548	29	21	to	to	ADP
dti-1548	29	22	hcc	hcc	PROPN
dti-1548	29	23	treatment	treatment	NOUN
dti-1548	29	24	.	.	PUNCT
dti-1548	30	1	therefore	therefore	ADV
dti-1548	30	2	,	,	PUNCT
dti-1548	30	3	therapeutic	therapeutic	ADJ
dti-1548	30	4	vulnerabilities	vulnerability	NOUN
dti-1548	30	5	should	should	AUX
dti-1548	30	6	be	be	AUX
dti-1548	30	7	studied	study	VERB
dti-1548	30	8	in	in	ADP
dti-1548	30	9	homogeneous	homogeneous	ADJ
dti-1548	30	10	groups	group	NOUN
dti-1548	30	11	of	of	ADP
dti-1548	30	12	hccs	hccs	NOUN
dti-1548	30	13	sharing	share	VERB
dti-1548	30	14	similar	similar	ADJ
dti-1548	30	15	drivers	driver	NOUN
dti-1548	30	16	of	of	ADP
dti-1548	30	17	the	the	DET
dti-1548	30	18	disease	disease	NOUN
dti-1548	30	19	(	(	PUNCT
dti-1548	30	20	3	3	NUM
dti-1548	30	21	)	)	PUNCT
dti-1548	30	22	.	.	PUNCT
dti-1548	31	1	in	in	ADP
dti-1548	31	2	egypt	egypt	PROPN
dti-1548	31	3	,	,	PUNCT
dti-1548	31	4	the	the	DET
dti-1548	31	5	estimated	estimate	VERB
dti-1548	31	6	national	national	ADJ
dti-1548	31	7	prevalence	prevalence	NOUN
dti-1548	31	8	of	of	ADP
dti-1548	31	9	hcv	hcv	NOUN
dti-1548	31	10	is	be	AUX
dti-1548	31	11	14.7	14.7	NUM
dti-1548	31	12	%	%	NOUN
dti-1548	31	13	,	,	PUNCT
dti-1548	31	14	which	which	PRON
dti-1548	31	15	is	be	AUX
dti-1548	31	16	the	the	DET
dti-1548	31	17	highest	high	ADJ
dti-1548	31	18	in	in	ADP
dti-1548	31	19	the	the	DET
dti-1548	31	20	world	world	NOUN
dti-1548	31	21	(	(	PUNCT
dti-1548	31	22	4	4	NUM
dti-1548	31	23	)	)	PUNCT
dti-1548	31	24	,	,	PUNCT
dti-1548	31	25	and	and	CCONJ
dti-1548	31	26	hccs	hccs	VERB
dti-1548	31	27	attributable	attributable	ADJ
dti-1548	31	28	to	to	PART
dti-1548	31	29	hcv	hcv	VERB
dti-1548	31	30	account	account	NOUN
dti-1548	31	31	for	for	ADP
dti-1548	31	32	around	around	ADV
dti-1548	31	33	50	50	NUM
dti-1548	31	34	%	%	NOUN
dti-1548	31	35	of	of	ADP
dti-1548	31	36	cases	case	NOUN
dti-1548	31	37	(	(	PUNCT
dti-1548	31	38	5	5	NUM
dti-1548	31	39	)	)	PUNCT
dti-1548	31	40	.	.	PUNCT
dti-1548	32	1	studies	study	NOUN
dti-1548	32	2	of	of	ADP
dti-1548	32	3	the	the	DET
dti-1548	32	4	hcv	hcv	NOUN
dti-1548	32	5	genome	genome	NOUN
dti-1548	32	6	confirmed	confirm	VERB
dti-1548	32	7	that	that	SCONJ
dti-1548	32	8	over	over	ADP
dti-1548	32	9	90	90	NUM
dti-1548	32	10	%	%	NOUN
dti-1548	32	11	of	of	ADP
dti-1548	32	12	egyptian	egyptian	ADJ
dti-1548	32	13	hcv	hcv	PROPN
dti-1548	32	14	isolates	isolate	NOUN
dti-1548	32	15	belong	belong	VERB
dti-1548	32	16	to	to	ADP
dti-1548	32	17	genotype	genotype	NOUN
dti-1548	32	18	4	4	NUM
dti-1548	32	19	(	(	PUNCT
dti-1548	32	20	6	6	NUM
dti-1548	32	21	)	)	PUNCT
dti-1548	32	22	.	.	PUNCT
dti-1548	33	1	the	the	DET
dti-1548	33	2	present	present	ADJ
dti-1548	33	3	study	study	NOUN
dti-1548	33	4	was	be	AUX
dti-1548	33	5	conducted	conduct	VERB
dti-1548	33	6	to	to	PART
dti-1548	33	7	characterize	characterize	VERB
dti-1548	33	8	the	the	DET
dti-1548	33	9	molecular	molecular	ADJ
dti-1548	33	10	alterations	alteration	NOUN
dti-1548	33	11	in	in	ADP
dti-1548	33	12	the	the	DET
dti-1548	33	13	insulin	insulin	NOUN
dti-1548	33	14	-	-	PUNCT
dti-1548	33	15	like	like	ADJ
dti-1548	33	16	growth	growth	NOUN
dti-1548	33	17	factor	factor	NOUN
dti-1548	33	18	1	1	NUM
dti-1548	33	19	receptor	receptor	NOUN
dti-1548	33	20	(	(	PUNCT
dti-1548	33	21	igf1r	igf1r	X
dti-1548	33	22	)	)	PUNCT
dti-1548	33	23	pathway	pathway	NOUN
dti-1548	33	24	in	in	ADP
dti-1548	33	25	a	a	DET
dti-1548	33	26	unified	unified	ADJ
dti-1548	33	27	cohort	cohort	NOUN
dti-1548	33	28	of	of	ADP
dti-1548	33	29	egyptian	egyptian	ADJ
dti-1548	33	30	hccs	hccs	NOUN
dti-1548	33	31	complicating	complicate	VERB
dti-1548	33	32	chronic	chronic	ADJ
dti-1548	33	33	hcv	hcv	NOUN
dti-1548	33	34	genotype	genotype	NOUN
dti-1548	33	35	4	4	NUM
dti-1548	33	36	.	.	PUNCT
dti-1548	34	1	the	the	DET
dti-1548	34	2	igf1r	igf1r	PROPN
dti-1548	34	3	pathway	pathway	NOUN
dti-1548	34	4	was	be	AUX
dti-1548	34	5	chosen	choose	VERB
dti-1548	34	6	as	as	SCONJ
dti-1548	34	7	its	its	PRON
dti-1548	34	8	activation	activation	NOUN
dti-1548	34	9	plays	play	VERB
dti-1548	34	10	an	an	DET
dti-1548	34	11	important	important	ADJ
dti-1548	34	12	role	role	NOUN
dti-1548	34	13	in	in	ADP
dti-1548	34	14	almost	almost	ADV
dti-1548	34	15	every	every	PRON
dti-1548	34	16	aspect	aspect	NOUN
dti-1548	34	17	of	of	ADP
dti-1548	34	18	cancer	cancer	NOUN
dti-1548	34	19	development	development	NOUN
dti-1548	34	20	,	,	PUNCT
dti-1548	34	21	including	include	VERB
dti-1548	34	22	cell	cell	NOUN
dti-1548	34	23	proliferation	proliferation	NOUN
dti-1548	34	24	,	,	PUNCT
dti-1548	34	25	neoplastic	neoplastic	ADJ
dti-1548	34	26	transformation	transformation	NOUN
dti-1548	34	27	,	,	PUNCT
dti-1548	34	28	cancer	cancer	NOUN
dti-1548	34	29	cell	cell	NOUN
dti-1548	34	30	survival	survival	NOUN
dti-1548	34	31	,	,	PUNCT
dti-1548	34	32	epithelial	epithelial	ADJ
dti-1548	34	33	to	to	ADP
dti-1548	34	34	mesenchymal	mesenchymal	ADJ
dti-1548	34	35	transition	transition	NOUN
dti-1548	34	36	(	(	PUNCT
dti-1548	34	37	emt	emt	PROPN
dti-1548	34	38	)	)	PUNCT
dti-1548	34	39	,	,	PUNCT
dti-1548	34	40	and	and	CCONJ
dti-1548	34	41	metastasis	metastasis	NOUN
dti-1548	34	42	(	(	PUNCT
dti-1548	34	43	7	7	NUM
dti-1548	34	44	)	)	PUNCT
dti-1548	34	45	and	and	CCONJ
dti-1548	34	46	that	that	SCONJ
dti-1548	34	47	igf1r	igf1r	DET
dti-1548	34	48	overexpression	overexpression	NOUN
dti-1548	34	49	correlated	correlate	VERB
dti-1548	34	50	with	with	ADP
dti-1548	34	51	aggressive	aggressive	ADJ
dti-1548	34	52	phenotype	phenotype	NOUN
dti-1548	34	53	in	in	ADP
dti-1548	34	54	cancer	cancer	NOUN
dti-1548	34	55	,	,	PUNCT
dti-1548	34	56	poor	poor	ADJ
dti-1548	34	57	clinical	clinical	ADJ
dti-1548	34	58	outcome	outcome	NOUN
dti-1548	34	59	,	,	PUNCT
dti-1548	34	60	and	and	CCONJ
dti-1548	34	61	therapy	therapy	NOUN
dti-1548	34	62	resistance	resistance	NOUN
dti-1548	34	63	(	(	PUNCT
dti-1548	34	64	8–10	8–10	NOUN
dti-1548	34	65	)	)	PUNCT
dti-1548	34	66	.	.	PUNCT
dti-1548	35	1	aim	aim	VERB
dti-1548	35	2	the	the	DET
dti-1548	35	3	present	present	ADJ
dti-1548	35	4	work	work	NOUN
dti-1548	35	5	aimed	aim	VERB
dti-1548	35	6	to	to	PART
dti-1548	35	7	identify	identify	VERB
dti-1548	35	8	the	the	DET
dti-1548	35	9	gene	gene	NOUN
dti-1548	35	10	expression	expression	NOUN
dti-1548	35	11	of	of	ADP
dti-1548	35	12	the	the	DET
dti-1548	35	13	different	different	ADJ
dti-1548	35	14	subcellular	subcellular	ADJ
dti-1548	35	15	components	component	NOUN
dti-1548	35	16	of	of	ADP
dti-1548	35	17	the	the	DET
dti-1548	35	18	igf1r	igf1r	ADJ
dti-1548	35	19	pathway	pathway	NOUN
dti-1548	35	20	in	in	ADP
dti-1548	35	21	egyptian	egyptian	ADJ
dti-1548	35	22	hccs	hccs	NOUN
dti-1548	35	23	complicating	complicate	VERB
dti-1548	35	24	chronic	chronic	ADJ
dti-1548	35	25	hcv	hcv	NOUN
dti-1548	35	26	genotype	genotype	NOUN
dti-1548	35	27	4	4	NUM
dti-1548	35	28	,	,	PUNCT
dti-1548	35	29	followed	follow	VERB
dti-1548	35	30	by	by	ADP
dti-1548	35	31	identification	identification	NOUN
dti-1548	35	32	of	of	ADP
dti-1548	35	33	the	the	DET
dti-1548	35	34	most	most	ADV
dti-1548	35	35	frequently	frequently	ADV
dti-1548	35	36	coregulated	coregulate	VERB
dti-1548	35	37	genes	gene	NOUN
dti-1548	35	38	,	,	PUNCT
dti-1548	35	39	correlation	correlation	NOUN
dti-1548	35	40	of	of	ADP
dti-1548	35	41	gene	gene	NOUN
dti-1548	35	42	expression	expression	NOUN
dti-1548	35	43	with	with	ADP
dti-1548	35	44	the	the	DET
dti-1548	35	45	different	different	ADJ
dti-1548	35	46	clinical	clinical	ADJ
dti-1548	35	47	and	and	CCONJ
dti-1548	35	48	pathological	pathological	ADJ
dti-1548	35	49	patient	patient	NOUN
dti-1548	35	50	and	and	CCONJ
dti-1548	35	51	tumor	tumor	NOUN
dti-1548	35	52	characteristics	characteristic	NOUN
dti-1548	35	53	,	,	PUNCT
dti-1548	35	54	and	and	CCONJ
dti-1548	35	55	determination	determination	NOUN
dti-1548	35	56	of	of	ADP
dti-1548	35	57	the	the	DET
dti-1548	35	58	activity	activity	NOUN
dti-1548	35	59	status	status	NOUN
dti-1548	35	60	of	of	ADP
dti-1548	35	61	involved	involved	ADJ
dti-1548	35	62	pathways	pathway	NOUN
dti-1548	35	63	.	.	PUNCT
dti-1548	36	1	materials	material	NOUN
dti-1548	36	2	two	two	NUM
dti-1548	36	3	groups	group	NOUN
dti-1548	36	4	were	be	AUX
dti-1548	36	5	included	include	VERB
dti-1548	36	6	in	in	ADP
dti-1548	36	7	the	the	DET
dti-1548	36	8	present	present	ADJ
dti-1548	36	9	study	study	NOUN
dti-1548	36	10	;	;	PUNCT
dti-1548	36	11	the	the	DET
dti-1548	36	12	study	study	NOUN
dti-1548	36	13	group	group	NOUN
dti-1548	36	14	comprised	comprise	VERB
dti-1548	36	15	32	32	NUM
dti-1548	36	16	formalin	formalin	NOUN
dti-1548	36	17	-	-	PUNCT
dti-1548	36	18	fixed	fix	VERB
dti-1548	36	19	,	,	PUNCT
dti-1548	36	20	paraffin	paraffin	NOUN
dti-1548	36	21	-	-	PUNCT
dti-1548	36	22	embedded	embed	VERB
dti-1548	36	23	(	(	PUNCT
dti-1548	36	24	ffpe	ffpe	NOUN
dti-1548	36	25	)	)	PUNCT
dti-1548	36	26	blocks	block	NOUN
dti-1548	36	27	from	from	ADP
dti-1548	36	28	32	32	NUM
dti-1548	36	29	egyptian	egyptian	ADJ
dti-1548	36	30	hccs	hccs	NOUN
dti-1548	36	31	complicating	complicate	VERB
dti-1548	36	32	chronic	chronic	ADJ
dti-1548	36	33	hcv	hcv	X
dti-1548	36	34	genotype	genotype	NOUN
dti-1548	36	35	4	4	NUM
dti-1548	36	36	etiology	etiology	NOUN
dti-1548	36	37	(	(	PUNCT
dti-1548	36	38	shown	show	VERB
dti-1548	36	39	as	as	ADP
dti-1548	36	40	positive	positive	ADJ
dti-1548	36	41	by	by	ADP
dti-1548	36	42	hcv	hcv	X
dti-1548	36	43	dna	dna	PROPN
dti-1548	36	44	pcr	pcr	PROPN
dti-1548	36	45	using	use	VERB
dti-1548	36	46	inno	inno	PROPN
dti-1548	36	47	-	-	PUNCT
dti-1548	36	48	lipa	lipa	NOUN
dti-1548	36	49	i	i	PROPN
dti-1548	36	50	and	and	CCONJ
dti-1548	36	51	ii	ii	NUM
dti-1548	36	52	)	)	PUNCT
dti-1548	36	53	.	.	PUNCT
dti-1548	37	1	twenty	twenty	NUM
dti-1548	37	2	-	-	PUNCT
dti-1548	37	3	four	four	NUM
dti-1548	37	4	out	out	ADP
dti-1548	37	5	of	of	ADP
dti-1548	37	6	32	32	NUM
dti-1548	37	7	were	be	AUX
dti-1548	37	8	segmentectomy	segmentectomy	NOUN
dti-1548	37	9	specimens	specimen	NOUN
dti-1548	37	10	,	,	PUNCT
dti-1548	37	11	while	while	SCONJ
dti-1548	37	12	8	8	NUM
dti-1548	37	13	out	out	ADP
dti-1548	37	14	of	of	ADP
dti-1548	37	15	32	32	NUM
dti-1548	37	16	were	be	AUX
dti-1548	37	17	liver	liver	NOUN
dti-1548	37	18	explants	explant	NOUN
dti-1548	37	19	,	,	PUNCT
dti-1548	37	20	and	and	CCONJ
dti-1548	37	21	the	the	DET
dti-1548	37	22	control	control	NOUN
dti-1548	37	23	group	group	NOUN
dti-1548	37	24	comprised	comprise	VERB
dti-1548	37	25	six	six	NUM
dti-1548	37	26	core	core	NOUN
dti-1548	37	27	biopsies	biopsy	NOUN
dti-1548	37	28	from	from	ADP
dti-1548	37	29	normal	normal	ADJ
dti-1548	37	30	liver	liver	NOUN
dti-1548	37	31	donors	donor	NOUN
dti-1548	37	32	.	.	PUNCT
dti-1548	38	1	inclusion	inclusion	NOUN
dti-1548	38	2	criteria	criterion	NOUN
dti-1548	38	3	were	be	AUX
dti-1548	38	4	hcv	hcv	NOUN
dti-1548	38	5	genotype	genotype	NOUN
dti-1548	38	6	4	4	NUM
dti-1548	38	7	etiology	etiology	NOUN
dti-1548	38	8	and	and	CCONJ
dti-1548	38	9	good	good	ADJ
dti-1548	38	10	quantity	quantity	NOUN
dti-1548	38	11	and	and	CCONJ
dti-1548	38	12	quality	quality	NOUN
dti-1548	38	13	of	of	ADP
dti-1548	38	14	extracted	extract	VERB
dti-1548	38	15	ribonucleic	ribonucleic	ADJ
dti-1548	38	16	acid	acid	NOUN
dti-1548	38	17	(	(	PUNCT
dti-1548	38	18	rna	rna	PROPN
dti-1548	38	19	)	)	PUNCT
dti-1548	38	20	as	as	SCONJ
dti-1548	38	21	measured	measure	VERB
dti-1548	38	22	by	by	ADP
dti-1548	38	23	nanodrop	nanodrop	PROPN
dti-1548	38	24	spectrophotometer	spectrophotometer	NOUN
dti-1548	38	25	(	(	PUNCT
dti-1548	38	26	a260	a260	NUM
dti-1548	38	27	:	:	PUNCT
dti-1548	38	28	a280	a280	PROPN
dti-1548	38	29	ratio	ratio	NOUN
dti-1548	38	30	1.9:2.0	1.9:2.0	NUM
dti-1548	38	31	indicated	indicate	VERB
dti-1548	38	32	pure	pure	ADJ
dti-1548	38	33	rna	rna	NOUN
dti-1548	38	34	)	)	PUNCT
dti-1548	38	35	.	.	PUNCT
dti-1548	39	1	exclusion	exclusion	NOUN
dti-1548	39	2	criteria	criterion	NOUN
dti-1548	39	3	included	include	VERB
dti-1548	39	4	positive	positive	ADJ
dti-1548	39	5	serology	serology	NOUN
dti-1548	39	6	for	for	ADP
dti-1548	39	7	anti	anti	ADJ
dti-1548	39	8	-	-	ADJ
dti-1548	39	9	hepatitis	hepatitis	ADJ
dti-1548	39	10	b	b	PROPN
dti-1548	39	11	virus	virus	NOUN
dti-1548	39	12	surface	surface	NOUN
dti-1548	39	13	antibody	antibody	NOUN
dti-1548	39	14	and	and	CCONJ
dti-1548	39	15	any	any	DET
dti-1548	39	16	hcc	hcc	PROPN
dti-1548	39	17	patient	patient	NOUN
dti-1548	39	18	who	who	PRON
dti-1548	39	19	has	have	AUX
dti-1548	39	20	received	receive	VERB
dti-1548	39	21	previous	previous	ADJ
dti-1548	39	22	neoadjuvant	neoadjuvant	ADJ
dti-1548	39	23	chemotherapy	chemotherapy	NOUN
dti-1548	39	24	(	(	PUNCT
dti-1548	39	25	including	include	VERB
dti-1548	39	26	transarterial	transarterial	ADJ
dti-1548	39	27	chemoembolization	chemoembolization	NOUN
dti-1548	39	28	)	)	PUNCT
dti-1548	39	29	.	.	PUNCT
dti-1548	40	1	to	to	PART
dti-1548	40	2	accurately	accurately	ADV
dti-1548	40	3	define	define	VERB
dti-1548	40	4	our	our	PRON
dti-1548	40	5	study	study	NOUN
dti-1548	40	6	population	population	NOUN
dti-1548	40	7	,	,	PUNCT
dti-1548	40	8	further	further	ADJ
dti-1548	40	9	identification	identification	NOUN
dti-1548	40	10	of	of	ADP
dti-1548	40	11	other	other	ADJ
dti-1548	40	12	known	know	VERB
dti-1548	40	13	hepatocarcinogens	hepatocarcinogen	NOUN
dti-1548	40	14	in	in	ADP
dti-1548	40	15	the	the	DET
dti-1548	40	16	egyptian	egyptian	ADJ
dti-1548	40	17	environment	environment	NOUN
dti-1548	40	18	was	be	AUX
dti-1548	40	19	performed	perform	VERB
dti-1548	40	20	,	,	PUNCT
dti-1548	40	21	including	include	VERB
dti-1548	40	22	:	:	PUNCT
dti-1548	40	23	1	1	X
dti-1548	40	24	)	)	PUNCT
dti-1548	40	25	hepatitis	hepatitis	PROPN
dti-1548	40	26	b	b	PROPN
dti-1548	40	27	core	core	NOUN
dti-1548	40	28	antigen	antigen	NOUN
dti-1548	40	29	(	(	PUNCT
dti-1548	40	30	hbcag	hbcag	NOUN
dti-1548	40	31	)	)	PUNCT
dti-1548	40	32	positivity	positivity	NOUN
dti-1548	40	33	by	by	ADP
dti-1548	40	34	immunohistochemistry	immunohistochemistry	NOUN
dti-1548	40	35	(	(	PUNCT
dti-1548	40	36	ihc	ihc	PROPN
dti-1548	40	37	)	)	PUNCT
dti-1548	40	38	(	(	PUNCT
dti-1548	40	39	denoting	denote	VERB
dti-1548	40	40	occult	occult	NOUN
dti-1548	40	41	hepatitis	hepatitis	PROPN
dti-1548	40	42	b	b	PROPN
dti-1548	40	43	virus	virus	NOUN
dti-1548	40	44	[	[	X
dti-1548	40	45	hbv	hbv	X
dti-1548	40	46	]	]	PUNCT
dti-1548	40	47	infection	infection	NOUN
dti-1548	40	48	)	)	PUNCT
dti-1548	40	49	was	be	AUX
dti-1548	40	50	found	find	VERB
dti-1548	40	51	in	in	ADP
dti-1548	40	52	7/29	7/29	NUM
dti-1548	40	53	of	of	ADP
dti-1548	40	54	our	our	PRON
dti-1548	40	55	hcc	hcc	PROPN
dti-1548	40	56	cases	case	NOUN
dti-1548	40	57	as	as	SCONJ
dti-1548	40	58	evidenced	evidence	VERB
dti-1548	40	59	by	by	ADP
dti-1548	40	60	cytoplasmic	cytoplasmic	ADJ
dti-1548	40	61	positivity	positivity	NOUN
dti-1548	40	62	to	to	ADP
dti-1548	40	63	the	the	DET
dti-1548	40	64	antibody	antibody	NOUN
dti-1548	40	65	.	.	PUNCT
dti-1548	41	1	2	2	X
dti-1548	41	2	)	)	PUNCT
dti-1548	41	3	aflatoxin	aflatoxin	NOUN
dti-1548	41	4	b1	b1	NOUN
dti-1548	41	5	-	-	PUNCT
dti-1548	41	6	dna	dna	PROPN
dti-1548	41	7	(	(	PUNCT
dti-1548	41	8	afb1	afb1	NOUN
dti-1548	41	9	-	-	PUNCT
dti-1548	41	10	dna	dna	PROPN
dti-1548	41	11	)	)	PUNCT
dti-1548	41	12	adduct	adduct	NOUN
dti-1548	41	13	positivity	positivity	NOUN
dti-1548	41	14	by	by	ADP
dti-1548	41	15	ihc	ihc	PROPN
dti-1548	41	16	was	be	AUX
dti-1548	41	17	found	find	VERB
dti-1548	41	18	to	to	PART
dti-1548	41	19	be	be	AUX
dti-1548	41	20	present	present	ADJ
dti-1548	41	21	in	in	ADP
dti-1548	41	22	16/29	16/29	NUM
dti-1548	41	23	of	of	ADP
dti-1548	41	24	our	our	PRON
dti-1548	41	25	cases	case	NOUN
dti-1548	41	26	as	as	SCONJ
dti-1548	41	27	evidenced	evidence	VERB
dti-1548	41	28	by	by	ADP
dti-1548	41	29	nuclear	nuclear	ADJ
dti-1548	41	30	positivity	positivity	NOUN
dti-1548	41	31	to	to	ADP
dti-1548	41	32	the	the	DET
dti-1548	41	33	antibody	antibody	NOUN
dti-1548	41	34	.	.	PUNCT
dti-1548	42	1	methods	method	NOUN
dti-1548	42	2	the	the	DET
dti-1548	42	3	protocol	protocol	NOUN
dti-1548	42	4	of	of	ADP
dti-1548	42	5	this	this	DET
dti-1548	42	6	study	study	NOUN
dti-1548	42	7	was	be	AUX
dti-1548	42	8	approved	approve	VERB
dti-1548	42	9	by	by	ADP
dti-1548	42	10	the	the	DET
dti-1548	42	11	ethics	ethic	NOUN
dti-1548	42	12	committee	committee	PROPN
dti-1548	42	13	of	of	ADP
dti-1548	42	14	the	the	DET
dti-1548	42	15	faculty	faculty	NOUN
dti-1548	42	16	of	of	ADP
dti-1548	42	17	medicine	medicine	NOUN
dti-1548	42	18	,	,	PUNCT
dti-1548	42	19	university	university	PROPN
dti-1548	42	20	of	of	ADP
dti-1548	42	21	alexandria	alexandria	PROPN
dti-1548	42	22	.	.	PUNCT
dti-1548	43	1	paraffin	paraffin	NOUN
dti-1548	43	2	blocks	block	NOUN
dti-1548	43	3	of	of	ADP
dti-1548	43	4	liver	liver	NOUN
dti-1548	43	5	biopsies	biopsy	NOUN
dti-1548	43	6	were	be	AUX
dti-1548	43	7	obtained	obtain	VERB
dti-1548	43	8	from	from	ADP
dti-1548	43	9	the	the	DET
dti-1548	43	10	archives	archive	NOUN
dti-1548	43	11	of	of	ADP
dti-1548	43	12	the	the	DET
dti-1548	43	13	pathology	pathology	NOUN
dti-1548	43	14	department	department	NOUN
dti-1548	43	15	at	at	ADP
dti-1548	43	16	the	the	DET
dti-1548	43	17	faculty	faculty	NOUN
dti-1548	43	18	of	of	ADP
dti-1548	43	19	medicine	medicine	NOUN
dti-1548	43	20	,	,	PUNCT
dti-1548	43	21	alexandria	alexandria	PROPN
dti-1548	43	22	university	university	PROPN
dti-1548	43	23	.	.	PUNCT
dti-1548	44	1	clinical	clinical	ADJ
dti-1548	44	2	data	datum	NOUN
dti-1548	44	3	were	be	AUX
dti-1548	44	4	collected	collect	VERB
dti-1548	44	5	from	from	ADP
dti-1548	44	6	the	the	DET
dti-1548	44	7	patients	patient	NOUN
dti-1548	44	8	’	'	PUNCT
dti-1548	44	9	files	file	NOUN
dti-1548	44	10	including	include	VERB
dti-1548	44	11	gender	gender	NOUN
dti-1548	44	12	,	,	PUNCT
dti-1548	44	13	age	age	NOUN
dti-1548	44	14	,	,	PUNCT
dti-1548	44	15	comorbidities	comorbiditie	NOUN
dti-1548	44	16	(	(	PUNCT
dti-1548	44	17	diabetes	diabete	NOUN
dti-1548	44	18	mellitus	mellitus	NOUN
dti-1548	44	19	and	and	CCONJ
dti-1548	44	20	obesity	obesity	NOUN
dti-1548	44	21	)	)	PUNCT
dti-1548	44	22	,	,	PUNCT
dti-1548	44	23	alfa	alfa	NOUN
dti-1548	44	24	-	-	PUNCT
dti-1548	44	25	fetoprotein	fetoprotein	PROPN
dti-1548	44	26	(	(	PUNCT
dti-1548	44	27	afp	afp	NOUN
dti-1548	44	28	)	)	PUNCT
dti-1548	44	29	levels	level	NOUN
dti-1548	44	30	,	,	PUNCT
dti-1548	44	31	liver	liver	NOUN
dti-1548	44	32	function	function	NOUN
dti-1548	44	33	tests	test	NOUN
dti-1548	44	34	(	(	PUNCT
dti-1548	44	35	alanine	alanine	NOUN
dti-1548	44	36	aminotransferase	aminotransferase	NOUN
dti-1548	44	37	[	[	X
dti-1548	44	38	alt	alt	X
dti-1548	44	39	]	]	X
dti-1548	44	40	,	,	PUNCT
dti-1548	45	1	aspartate	aspartate	ADJ
dti-1548	45	2	transaminase	transaminase	NOUN
dti-1548	46	1	[	[	X
dti-1548	46	2	ast	ast	X
dti-1548	46	3	]	]	X
dti-1548	46	4	,	,	PUNCT
dti-1548	46	5	bilirubin	bilirubin	NOUN
dti-1548	46	6	,	,	PUNCT
dti-1548	46	7	and	and	CCONJ
dti-1548	46	8	albumin	albumin	NOUN
dti-1548	46	9	)	)	PUNCT
dti-1548	46	10	,	,	PUNCT
dti-1548	46	11	hemoglobin	hemoglobin	NOUN
dti-1548	46	12	concentration	concentration	NOUN
dti-1548	46	13	,	,	PUNCT
dti-1548	46	14	and	and	CCONJ
dti-1548	46	15	complete	complete	ADJ
dti-1548	46	16	blood	blood	NOUN
dti-1548	46	17	picture	picture	NOUN
dti-1548	46	18	.	.	PUNCT
dti-1548	47	1	gross	gross	ADJ
dti-1548	47	2	pathologic	pathologic	ADJ
dti-1548	47	3	examination	examination	NOUN
dti-1548	47	4	of	of	ADP
dti-1548	47	5	hcc	hcc	PROPN
dti-1548	47	6	tumors	tumor	NOUN
dti-1548	47	7	specifically	specifically	ADV
dti-1548	47	8	addressed	address	VERB
dti-1548	47	9	tumor	tumor	NOUN
dti-1548	47	10	size	size	NOUN
dti-1548	47	11	,	,	PUNCT
dti-1548	47	12	multifocality	multifocality	NOUN
dti-1548	47	13	,	,	PUNCT
dti-1548	47	14	gross	gross	ADJ
dti-1548	47	15	capsulation	capsulation	NOUN
dti-1548	47	16	,	,	PUNCT
dti-1548	47	17	gross	gross	ADJ
dti-1548	47	18	necrosis	necrosis	NOUN
dti-1548	47	19	,	,	PUNCT
dti-1548	47	20	satellites	satellite	NOUN
dti-1548	47	21	,	,	PUNCT
dti-1548	47	22	and	and	CCONJ
dti-1548	47	23	bile	bile	NOUN
dti-1548	47	24	production	production	NOUN
dti-1548	47	25	.	.	PUNCT
dti-1548	48	1	histopathologic	histopathologic	PROPN
dti-1548	48	2	study	study	NOUN
dti-1548	48	3	using	use	VERB
dti-1548	48	4	5	5	NUM
dti-1548	48	5	-	-	PUNCT
dti-1548	48	6	μm	μm	NUM
dti-1548	48	7	-	-	PUNCT
dti-1548	48	8	thick	thick	ADJ
dti-1548	48	9	sections	section	NOUN
dti-1548	48	10	assessed	assess	VERB
dti-1548	48	11	pathologic	pathologic	ADJ
dti-1548	48	12	tumor	tumor	NOUN
dti-1548	48	13	grade	grade	NOUN
dti-1548	48	14	(	(	PUNCT
dti-1548	48	15	was	be	AUX
dti-1548	48	16	performed	perform	VERB
dti-1548	48	17	according	accord	VERB
dti-1548	48	18	to	to	ADP
dti-1548	48	19	the	the	DET
dti-1548	48	20	edmondson	edmondson	PROPN
dti-1548	48	21	and	and	CCONJ
dti-1548	48	22	steiner	steiner	NOUN
dti-1548	48	23	grading	grade	VERB
dti-1548	48	24	system	system	NOUN
dti-1548	48	25	for	for	ADP
dti-1548	48	26	hcc	hcc	PROPN
dti-1548	48	27	)	)	PUNCT
dti-1548	48	28	,	,	PUNCT
dti-1548	48	29	histologic	histologic	NOUN
dti-1548	48	30	pattern	pattern	NOUN
dti-1548	48	31	,	,	PUNCT
dti-1548	48	32	cell	cell	NOUN
dti-1548	48	33	type	type	NOUN
dti-1548	48	34	(	(	PUNCT
dti-1548	48	35	including	include	VERB
dti-1548	48	36	giant	giant	ADJ
dti-1548	48	37	cells	cell	NOUN
dti-1548	48	38	and	and	CCONJ
dti-1548	48	39	clear	clear	ADJ
dti-1548	48	40	cells	cell	NOUN
dti-1548	48	41	)	)	PUNCT
dti-1548	48	42	,	,	PUNCT
dti-1548	48	43	and	and	CCONJ
dti-1548	48	44	vascular	vascular	ADJ
dti-1548	48	45	invasion	invasion	NOUN
dti-1548	48	46	.	.	PUNCT
dti-1548	49	1	the	the	DET
dti-1548	49	2	presence	presence	NOUN
dti-1548	49	3	of	of	ADP
dti-1548	49	4	dysplastic	dysplastic	ADJ
dti-1548	49	5	nodules	nodule	NOUN
dti-1548	49	6	outside	outside	ADP
dti-1548	49	7	hcc	hcc	PROPN
dti-1548	49	8	and	and	CCONJ
dti-1548	49	9	pathological	pathological	ADJ
dti-1548	49	10	tumor	tumor	NOUN
dti-1548	49	11	-	-	PUNCT
dti-1548	49	12	node	node	NOUN
dti-1548	49	13	-	-	PUNCT
dti-1548	49	14	metastasis	metastasis	NOUN
dti-1548	49	15	(	(	PUNCT
dti-1548	49	16	ptnm	ptnm	NOUN
dti-1548	49	17	)	)	PUNCT
dti-1548	49	18	staging	staging	NOUN
dti-1548	49	19	(	(	PUNCT
dti-1548	49	20	according	accord	VERB
dti-1548	49	21	to	to	ADP
dti-1548	49	22	the	the	DET
dti-1548	49	23	ptnm	ptnm	NOUN
dti-1548	49	24	staging	staging	NOUN
dti-1548	49	25	system	system	NOUN
dti-1548	49	26	of	of	ADP
dti-1548	49	27	the	the	DET
dti-1548	49	28	american	american	PROPN
dti-1548	49	29	joint	joint	PROPN
dti-1548	49	30	committee	committee	PROPN
dti-1548	49	31	on	on	ADP
dti-1548	49	32	cancer	cancer	PROPN
dti-1548	49	33	8th	8th	PROPN
dti-1548	49	34	edition	edition	NOUN
dti-1548	49	35	[	[	X
dti-1548	49	36	ajcc	ajcc	X
dti-1548	49	37	]	]	PUNCT
dti-1548	49	38	)	)	PUNCT
dti-1548	49	39	was	be	AUX
dti-1548	49	40	also	also	ADV
dti-1548	49	41	noted	note	VERB
dti-1548	49	42	.	.	PUNCT
dti-1548	50	1	real	real	ADJ
dti-1548	50	2	-	-	PUNCT
dti-1548	50	3	time	time	NOUN
dti-1548	50	4	quantitative	quantitative	ADJ
dti-1548	50	5	reverse	reverse	ADJ
dti-1548	50	6	transcription	transcription	NOUN
dti-1548	50	7	pcr	pcr	ADJ
dti-1548	50	8	preparation	preparation	NOUN
dti-1548	50	9	of	of	ADP
dti-1548	50	10	the	the	DET
dti-1548	50	11	paraffin	paraffin	NOUN
dti-1548	50	12	blocks	block	NOUN
dti-1548	50	13	and	and	CCONJ
dti-1548	50	14	obtaining	obtain	VERB
dti-1548	50	15	tissue	tissue	NOUN
dti-1548	50	16	sections	section	NOUN
dti-1548	50	17	1	1	NUM
dti-1548	50	18	)	)	PUNCT
dti-1548	50	19	by	by	ADP
dti-1548	50	20	trimming	trim	VERB
dti-1548	50	21	off	off	ADP
dti-1548	50	22	the	the	DET
dti-1548	50	23	excess	excess	ADJ
dti-1548	50	24	paraffin	paraffin	NOUN
dti-1548	50	25	from	from	ADP
dti-1548	50	26	the	the	DET
dti-1548	50	27	edges	edge	NOUN
dti-1548	50	28	of	of	ADP
dti-1548	50	29	the	the	DET
dti-1548	50	30	specimen	speciman	NOUN
dti-1548	50	31	to	to	PART
dti-1548	50	32	facilitate	facilitate	VERB
dti-1548	50	33	deparaffinization	deparaffinization	NOUN
dti-1548	50	34	.	.	PUNCT
dti-1548	51	1	2	2	X
dti-1548	51	2	)	)	PUNCT
dti-1548	51	3	then	then	ADV
dti-1548	51	4	two	two	NUM
dti-1548	51	5	sections	section	NOUN
dti-1548	51	6	,	,	PUNCT
dti-1548	51	7	5	5	NUM
dti-1548	51	8	μm	μm	NOUN
dti-1548	51	9	thick	thick	ADJ
dti-1548	51	10	each	each	PRON
dti-1548	51	11	,	,	PUNCT
dti-1548	51	12	were	be	AUX
dti-1548	51	13	cut	cut	VERB
dti-1548	51	14	from	from	ADP
dti-1548	51	15	each	each	DET
dti-1548	51	16	block	block	NOUN
dti-1548	51	17	and	and	CCONJ
dti-1548	51	18	placed	place	VERB
dti-1548	51	19	in	in	ADP
dti-1548	51	20	a	a	DET
dti-1548	51	21	2	2	NUM
dti-1548	51	22	ml	ml	NOUN
dti-1548	51	23	nuclease	nuclease	NOUN
dti-1548	51	24	-	-	PUNCT
dti-1548	51	25	free	free	ADJ
dti-1548	51	26	microfuge	microfuge	NOUN
dti-1548	51	27	tube	tube	NOUN
dti-1548	51	28	.	.	PUNCT
dti-1548	52	1	total	total	ADJ
dti-1548	52	2	rna	rna	PROPN
dti-1548	52	3	was	be	AUX
dti-1548	52	4	extracted	extract	VERB
dti-1548	52	5	from	from	ADP
dti-1548	52	6	ffpe	ffpe	ADJ
dti-1548	52	7	tumor	tumor	NOUN
dti-1548	52	8	sections	section	NOUN
dti-1548	52	9	using	use	VERB
dti-1548	52	10	the	the	DET
dti-1548	52	11	rneasy	rneasy	NOUN
dti-1548	52	12	®	®	NOUN
dti-1548	52	13	ffpe	ffpe	NOUN
dti-1548	52	14	kit	kit	NOUN
dti-1548	52	15	for	for	ADP
dti-1548	52	16	purification	purification	NOUN
dti-1548	52	17	of	of	ADP
dti-1548	52	18	total	total	ADJ
dti-1548	52	19	rna	rna	NOUN
dti-1548	52	20	from	from	ADP
dti-1548	52	21	ffpe	ffpe	ADJ
dti-1548	52	22	tissue	tissue	NOUN
dti-1548	52	23	sections	section	NOUN
dti-1548	52	24	(	(	PUNCT
dti-1548	52	25	qiagen	qiagen	PROPN
dti-1548	52	26	,	,	PUNCT
dti-1548	52	27	hilden	hilden	PROPN
dti-1548	52	28	,	,	PUNCT
dti-1548	52	29	germany	germany	PROPN
dti-1548	52	30	,	,	PUNCT
dti-1548	52	31	cat	cat	NOUN
dti-1548	52	32	.	.	PUNCT
dti-1548	53	1	no	no	INTJ
dti-1548	53	2	.	.	PUNCT
dti-1548	53	3	:	:	PUNCT
dti-1548	54	1	73504	73504	NUM
dti-1548	54	2	)	)	PUNCT
dti-1548	54	3	according	accord	VERB
dti-1548	54	4	to	to	ADP
dti-1548	54	5	the	the	DET
dti-1548	54	6	manufacturer	manufacturer	NOUN
dti-1548	54	7	’s	’s	PART
dti-1548	54	8	instructions	instruction	NOUN
dti-1548	54	9	.	.	PUNCT
dti-1548	55	1	its	its	PRON
dti-1548	55	2	main	main	ADJ
dti-1548	55	3	principle	principle	NOUN
dti-1548	55	4	is	be	AUX
dti-1548	55	5	to	to	PART
dti-1548	55	6	remove	remove	VERB
dti-1548	55	7	all	all	DET
dti-1548	55	8	the	the	DET
dti-1548	55	9	paraffin	paraffin	NOUN
dti-1548	55	10	,	,	PUNCT
dti-1548	55	11	reverse	reverse	ADJ
dti-1548	55	12	formalin	formalin	NOUN
dti-1548	55	13	-	-	PUNCT
dti-1548	55	14	induced	induce	VERB
dti-1548	55	15	cross	cross	NOUN
dti-1548	55	16	-	-	ADJ
dti-1548	55	17	linking	link	VERB
dti-1548	55	18	in	in	ADP
dti-1548	55	19	the	the	DET
dti-1548	55	20	nucleic	nucleic	ADJ
dti-1548	55	21	acid	acid	NOUN
dti-1548	55	22	,	,	PUNCT
dti-1548	55	23	and	and	CCONJ
dti-1548	55	24	prevent	prevent	VERB
dti-1548	55	25	any	any	DET
dti-1548	55	26	further	further	ADJ
dti-1548	55	27	degradation	degradation	NOUN
dti-1548	55	28	in	in	ADP
dti-1548	55	29	the	the	DET
dti-1548	55	30	rna	rna	NOUN
dti-1548	55	31	that	that	PRON
dti-1548	55	32	is	be	AUX
dti-1548	55	33	known	know	VERB
dti-1548	55	34	to	to	PART
dti-1548	55	35	be	be	AUX
dti-1548	55	36	induced	induce	VERB
dti-1548	55	37	by	by	ADP
dti-1548	55	38	formalin	formalin	NOUN
dti-1548	55	39	and	and	CCONJ
dti-1548	55	40	finally	finally	ADV
dti-1548	55	41	to	to	PART
dti-1548	55	42	eliminate	eliminate	VERB
dti-1548	55	43	all	all	DET
dti-1548	55	44	genomic	genomic	ADJ
dti-1548	55	45	dna	dna	NOUN
dti-1548	55	46	.	.	PUNCT
dti-1548	56	1	the	the	DET
dti-1548	56	2	concentration	concentration	NOUN
dti-1548	56	3	and	and	CCONJ
dti-1548	56	4	purity	purity	NOUN
dti-1548	56	5	of	of	ADP
dti-1548	56	6	extracted	extract	VERB
dti-1548	56	7	rna	rna	NOUN
dti-1548	56	8	were	be	AUX
dti-1548	56	9	determined	determine	VERB
dti-1548	56	10	using	use	VERB
dti-1548	56	11	a	a	DET
dti-1548	56	12	nanodrop	nanodrop	NOUN
dti-1548	56	13	nd-1000	nd-1000	NOUN
dti-1548	56	14	spectrophotometer	spectrophotometer	NOUN
dti-1548	56	15	.	.	PUNCT
dti-1548	57	1	samples	sample	NOUN
dti-1548	57	2	were	be	AUX
dti-1548	57	3	accepted	accept	VERB
dti-1548	57	4	when	when	SCONJ
dti-1548	57	5	the	the	DET
dti-1548	57	6	a260	a260	PROPN
dti-1548	57	7	/	/	SYM
dti-1548	57	8	a280	a280	PROPN
dti-1548	57	9	ratio	ratio	NOUN
dti-1548	57	10	(	(	PUNCT
dti-1548	57	11	nucleic	nucleic	ADJ
dti-1548	57	12	acid	acid	NOUN
dti-1548	57	13	/	/	SYM
dti-1548	57	14	protein	protein	NOUN
dti-1548	57	15	absorbance	absorbance	NOUN
dti-1548	57	16	)	)	PUNCT
dti-1548	57	17	was	be	AUX
dti-1548	57	18	≥1.9	≥1.9	VERB
dti-1548	57	19	.	.	PUNCT
dti-1548	58	1	reverse	reverse	ADJ
dti-1548	58	2	transcription	transcription	NOUN
dti-1548	58	3	of	of	ADP
dti-1548	58	4	extracted	extract	VERB
dti-1548	58	5	rna	rna	NOUN
dti-1548	58	6	(	(	PUNCT
dti-1548	58	7	0.5	0.5	NUM
dti-1548	58	8	µg	µg	ADV
dti-1548	58	9	[	[	X
dti-1548	58	10	500	500	NUM
dti-1548	58	11	ng	ng	NOUN
dti-1548	58	12	]	]	PUNCT
dti-1548	58	13	of	of	ADP
dti-1548	58	14	rna	rna	PROPN
dti-1548	58	15	was	be	AUX
dti-1548	58	16	used	use	VERB
dti-1548	58	17	for	for	ADP
dti-1548	58	18	all	all	DET
dti-1548	58	19	experimental	experimental	ADJ
dti-1548	58	20	runs	run	NOUN
dti-1548	58	21	)	)	PUNCT
dti-1548	58	22	to	to	PART
dti-1548	58	23	complementary	complementary	ADJ
dti-1548	58	24	dna	dna	PROPN
dti-1548	58	25	(	(	PUNCT
dti-1548	58	26	cdna	cdna	PROPN
dti-1548	58	27	)	)	PUNCT
dti-1548	58	28	was	be	AUX
dti-1548	58	29	done	do	VERB
dti-1548	58	30	using	use	VERB
dti-1548	58	31	rt2	rt2	PROPN
dti-1548	58	32	first	first	ADJ
dti-1548	58	33	strand	strand	NOUN
dti-1548	58	34	kit	kit	NOUN
dti-1548	58	35	(	(	PUNCT
dti-1548	58	36	qiagen	qiagen	PROPN
dti-1548	58	37	,	,	PUNCT
dti-1548	58	38	hilden	hilden	PROPN
dti-1548	58	39	,	,	PUNCT
dti-1548	58	40	germany	germany	PROPN
dti-1548	58	41	,	,	PUNCT
dti-1548	58	42	cat	cat	NOUN
dti-1548	58	43	.	.	PUNCT
dti-1548	59	1	no	no	INTJ
dti-1548	59	2	.	.	PUNCT
dti-1548	59	3	:	:	PUNCT
dti-1548	60	1	330401	330401	NUM
dti-1548	60	2	)	)	PUNCT
dti-1548	60	3	according	accord	VERB
dti-1548	60	4	to	to	ADP
dti-1548	60	5	the	the	DET
dti-1548	60	6	manufacturer	manufacturer	NOUN
dti-1548	60	7	’s	’s	PART
dti-1548	60	8	instructions	instruction	NOUN
dti-1548	60	9	.	.	PUNCT
dti-1548	61	1	rt2	rt2	PROPN
dti-1548	61	2	sybr	sybr	PROPN
dti-1548	61	3	green	green	PROPN
dti-1548	61	4	rox	rox	PROPN
dti-1548	61	5	qpcr	qpcr	ADV
dti-1548	61	6	mastermix	mastermix	NOUN
dti-1548	61	7	(	(	PUNCT
dti-1548	61	8	qiagen	qiagen	PROPN
dti-1548	61	9	,	,	PUNCT
dti-1548	61	10	hilden	hilden	PROPN
dti-1548	61	11	,	,	PUNCT
dti-1548	61	12	germany	germany	PROPN
dti-1548	61	13	,	,	PUNCT
dti-1548	61	14	cat	cat	NOUN
dti-1548	61	15	.	.	PUNCT
dti-1548	62	1	no	no	INTJ
dti-1548	62	2	.	.	PUNCT
dti-1548	62	3	:	:	PUNCT
dti-1548	63	1	330523	330523	NUM
dti-1548	63	2	)	)	PUNCT
dti-1548	63	3	was	be	AUX
dti-1548	63	4	added	add	VERB
dti-1548	63	5	to	to	ADP
dti-1548	63	6	the	the	DET
dti-1548	63	7	cdna	cdna	PROPN
dti-1548	63	8	.	.	PUNCT
dti-1548	64	1	the	the	DET
dti-1548	64	2	mixture	mixture	NOUN
dti-1548	64	3	was	be	AUX
dti-1548	64	4	aliquoted	aliquote	VERB
dti-1548	64	5	into	into	ADP
dti-1548	64	6	the	the	DET
dti-1548	64	7	96	96	NUM
dti-1548	64	8	wells	well	NOUN
dti-1548	64	9	of	of	ADP
dti-1548	64	10	the	the	DET
dti-1548	64	11	commercially	commercially	ADV
dti-1548	64	12	available	available	ADJ
dti-1548	64	13	rt²	rt²	NOUN
dti-1548	64	14	profiler	profiler	NOUN
dti-1548	64	15	™	™	VERB
dti-1548	64	16	pcr	pcr	NOUN
dti-1548	64	17	array	array	VERB
dti-1548	64	18	human	human	ADJ
dti-1548	64	19	insulin	insulin	NOUN
dti-1548	64	20	signaling	signal	VERB
dti-1548	64	21	pathway	pathway	NOUN
dti-1548	64	22	(	(	PUNCT
dti-1548	64	23	pahs-030za	pahs-030za	PROPN
dti-1548	64	24	)	)	PUNCT
dti-1548	64	25	(	(	PUNCT
dti-1548	64	26	qiagen	qiagen	PROPN
dti-1548	64	27	,	,	PUNCT
dti-1548	64	28	mabrouk	mabrouk	PRON
dti-1548	64	29	et	et	NOUN
dti-1548	64	30	al	al	PROPN
dti-1548	64	31	3	3	NUM
dti-1548	65	1	©	©	PROPN
dti-1548	65	2	2020	2020	NUM
dti-1548	65	3	the	the	DET
dti-1548	65	4	authors	author	NOUN
dti-1548	65	5	.	.	PUNCT
dti-1548	66	1	published	publish	VERB
dti-1548	66	2	by	by	ADP
dti-1548	66	3	aboutscience	aboutscience	NOUN
dti-1548	66	4	hilden	hilden	PROPN
dti-1548	66	5	,	,	PUNCT
dti-1548	66	6	germany	germany	PROPN
dti-1548	66	7	,	,	PUNCT
dti-1548	66	8	cat	cat	NOUN
dti-1548	66	9	.	.	PUNCT
dti-1548	67	1	no	no	INTJ
dti-1548	67	2	.	.	PUNCT
dti-1548	67	3	:	:	PUNCT
dti-1548	68	1	330231	330231	NUM
dti-1548	68	2	)	)	PUNCT
dti-1548	68	3	containing	contain	VERB
dti-1548	68	4	primer	primer	NOUN
dti-1548	68	5	assays	assay	NOUN
dti-1548	68	6	for	for	ADP
dti-1548	68	7	84	84	NUM
dti-1548	68	8	genes	gene	NOUN
dti-1548	68	9	concerning	concern	VERB
dti-1548	68	10	the	the	DET
dti-1548	68	11	human	human	ADJ
dti-1548	68	12	insulin	insulin	NOUN
dti-1548	68	13	signaling	signal	VERB
dti-1548	68	14	pathway	pathway	NOUN
dti-1548	68	15	,	,	PUNCT
dti-1548	68	16	including	include	VERB
dti-1548	68	17	genes	gene	NOUN
dti-1548	68	18	of	of	ADP
dti-1548	68	19	the	the	DET
dti-1548	68	20	phosphatidylinositol-3	phosphatidylinositol-3	PROPN
dti-1548	68	21	-	-	PUNCT
dti-1548	68	22	kinase	kinase	NOUN
dti-1548	68	23	(	(	PUNCT
dti-1548	68	24	pi3k	pi3k	PROPN
dti-1548	68	25	)	)	PUNCT
dti-1548	68	26	and	and	CCONJ
dti-1548	68	27	the	the	DET
dti-1548	68	28	mitogen	mitogen	NOUN
dti-1548	68	29	-	-	PUNCT
dti-1548	68	30	activated	activate	VERB
dti-1548	68	31	protein	protein	NOUN
dti-1548	68	32	kinase	kinase	NOUN
dti-1548	68	33	(	(	PUNCT
dti-1548	68	34	mapk	mapk	NOUN
dti-1548	68	35	)	)	PUNCT
dti-1548	68	36	signaling	signal	VERB
dti-1548	68	37	pathways	pathway	NOUN
dti-1548	68	38	that	that	PRON
dti-1548	68	39	are	be	AUX
dti-1548	68	40	the	the	DET
dti-1548	68	41	two	two	NUM
dti-1548	68	42	major	major	ADJ
dti-1548	68	43	downstream	downstream	NOUN
dti-1548	68	44	signaling	signal	VERB
dti-1548	68	45	pathways	pathway	NOUN
dti-1548	68	46	for	for	ADP
dti-1548	68	47	igf1r	igf1r	DET
dti-1548	68	48	signaling	signal	VERB
dti-1548	68	49	(	(	PUNCT
dti-1548	68	50	11	11	NUM
dti-1548	68	51	)	)	PUNCT
dti-1548	68	52	and	and	CCONJ
dti-1548	68	53	also	also	ADV
dti-1548	68	54	genes	gene	NOUN
dti-1548	68	55	involved	involve	VERB
dti-1548	68	56	in	in	ADP
dti-1548	68	57	carbohydrate	carbohydrate	NOUN
dti-1548	68	58	,	,	PUNCT
dti-1548	68	59	lipid	lipid	NOUN
dti-1548	68	60	,	,	PUNCT
dti-1548	68	61	and	and	CCONJ
dti-1548	68	62	protein	protein	NOUN
dti-1548	68	63	metabolism	metabolism	NOUN
dti-1548	68	64	;	;	PUNCT
dti-1548	68	65	transcription	transcription	NOUN
dti-1548	68	66	factors	factor	NOUN
dti-1548	68	67	and	and	CCONJ
dti-1548	68	68	transcription	transcription	NOUN
dti-1548	68	69	regulators	regulator	NOUN
dti-1548	68	70	;	;	PUNCT
dti-1548	68	71	genes	gene	NOUN
dti-1548	68	72	involved	involve	VERB
dti-1548	68	73	in	in	ADP
dti-1548	68	74	cell	cell	NOUN
dti-1548	68	75	proliferation	proliferation	NOUN
dti-1548	68	76	,	,	PUNCT
dti-1548	68	77	growth	growth	NOUN
dti-1548	68	78	and	and	CCONJ
dti-1548	68	79	differentiation	differentiation	NOUN
dti-1548	68	80	(	(	PUNCT
dti-1548	68	81	12	12	NUM
dti-1548	68	82	)	)	PUNCT
dti-1548	68	83	;	;	PUNCT
dti-1548	68	84	and	and	CCONJ
dti-1548	68	85	five	five	NUM
dti-1548	68	86	housekeeping	housekeeping	NOUN
dti-1548	68	87	genes	gene	NOUN
dti-1548	68	88	(	(	PUNCT
dti-1548	68	89	hkgs	hkgs	NOUN
dti-1548	68	90	)	)	PUNCT
dti-1548	68	91	.	.	PUNCT
dti-1548	69	1	in	in	ADP
dti-1548	69	2	addition	addition	NOUN
dti-1548	69	3	,	,	PUNCT
dti-1548	69	4	there	there	PRON
dti-1548	69	5	were	be	VERB
dti-1548	69	6	one	one	NUM
dti-1548	69	7	genomic	genomic	ADJ
dti-1548	69	8	dna	dna	NOUN
dti-1548	69	9	control	control	NOUN
dti-1548	69	10	,	,	PUNCT
dti-1548	69	11	three	three	NUM
dti-1548	69	12	reverse	reverse	ADJ
dti-1548	69	13	transcription	transcription	NOUN
dti-1548	69	14	controls	control	NOUN
dti-1548	69	15	,	,	PUNCT
dti-1548	69	16	and	and	CCONJ
dti-1548	69	17	three	three	NUM
dti-1548	69	18	positive	positive	ADJ
dti-1548	69	19	pcr	pcr	ADJ
dti-1548	69	20	controls	control	NOUN
dti-1548	69	21	(	(	PUNCT
dti-1548	69	22	the	the	DET
dti-1548	69	23	full	full	ADJ
dti-1548	69	24	list	list	NOUN
dti-1548	69	25	of	of	ADP
dti-1548	69	26	genes	gene	NOUN
dti-1548	69	27	can	can	AUX
dti-1548	69	28	be	be	AUX
dti-1548	69	29	found	find	VERB
dti-1548	69	30	in	in	ADP
dti-1548	69	31	the	the	DET
dti-1548	69	32	supplementary	supplementary	ADJ
dti-1548	69	33	file	file	NOUN
dti-1548	69	34	)	)	PUNCT
dti-1548	69	35	.	.	PUNCT
dti-1548	70	1	pcr	pcr	PROPN
dti-1548	70	2	is	be	AUX
dti-1548	70	3	then	then	ADV
dti-1548	70	4	performed	perform	VERB
dti-1548	70	5	using	use	VERB
dti-1548	70	6	the	the	DET
dti-1548	70	7	applied	apply	VERB
dti-1548	70	8	biosystems	biosystem	NOUN
dti-1548	70	9	®	®	VERB
dti-1548	70	10	7500	7500	NUM
dti-1548	70	11	real	real	ADJ
dti-1548	70	12	-	-	PUNCT
dti-1548	70	13	time	time	NOUN
dti-1548	70	14	pcr	pcr	NOUN
dti-1548	70	15	system	system	NOUN
dti-1548	70	16	(	(	PUNCT
dti-1548	70	17	thermofisher	thermofisher	PRON
dti-1548	70	18	scientific	scientific	ADJ
dti-1548	70	19	,	,	PUNCT
dti-1548	70	20	foster	foster	ADJ
dti-1548	70	21	city	city	NOUN
dti-1548	70	22	,	,	PUNCT
dti-1548	70	23	ca	ca	PROPN
dti-1548	70	24	,	,	PUNCT
dti-1548	70	25	usa	usa	PROPN
dti-1548	70	26	)	)	PUNCT
dti-1548	70	27	.	.	PUNCT
dti-1548	71	1	finally	finally	ADV
dti-1548	71	2	,	,	PUNCT
dti-1548	71	3	relative	relative	ADJ
dti-1548	71	4	expression	expression	NOUN
dti-1548	71	5	is	be	AUX
dti-1548	71	6	determined	determine	VERB
dti-1548	71	7	using	use	VERB
dti-1548	71	8	the	the	DET
dti-1548	71	9	δδct	δδct	NOUN
dti-1548	71	10	method	method	NOUN
dti-1548	71	11	using	use	VERB
dti-1548	71	12	the	the	DET
dti-1548	71	13	rt2	rt2	PROPN
dti-1548	71	14	profiler	profiler	NOUN
dti-1548	71	15	pcr	pcr	PROPN
dti-1548	71	16	array	array	NOUN
dti-1548	71	17	data	datum	NOUN
dti-1548	71	18	analysis	analysis	NOUN
dti-1548	71	19	webportal	webportal	NOUN
dti-1548	71	20	(	(	PUNCT
dti-1548	71	21	at	at	ADP
dti-1548	71	22	www.sabiosciences.com/	www.sabiosciences.com/	NOUN
dti-1548	71	23	pcrarraydataanalysis.php	pcrarraydataanalysis.php	PROPN
dti-1548	71	24	)	)	PUNCT
dti-1548	71	25	.	.	PUNCT
dti-1548	72	1	two	two	NUM
dti-1548	72	2	hkgs	hkgs	NOUN
dti-1548	72	3	with	with	ADP
dti-1548	72	4	the	the	DET
dti-1548	72	5	lowest	low	ADJ
dti-1548	72	6	standard	standard	ADJ
dti-1548	72	7	deviations	deviation	NOUN
dti-1548	72	8	and	and	CCONJ
dti-1548	72	9	most	most	ADV
dti-1548	72	10	stable	stable	ADJ
dti-1548	72	11	expression	expression	NOUN
dti-1548	72	12	across	across	ADP
dti-1548	72	13	replicates	replicate	NOUN
dti-1548	72	14	were	be	AUX
dti-1548	72	15	selected	select	VERB
dti-1548	72	16	for	for	ADP
dti-1548	72	17	data	datum	NOUN
dti-1548	72	18	normalization	normalization	NOUN
dti-1548	72	19	:	:	PUNCT
dti-1548	72	20	beta-2	beta-2	PROPN
dti-1548	72	21	-	-	PUNCT
dti-1548	72	22	microglobulin	microglobulin	PROPN
dti-1548	72	23	(	(	PUNCT
dti-1548	72	24	b2	b2	PROPN
dti-1548	72	25	m	m	NOUN
dti-1548	72	26	)	)	PUNCT
dti-1548	72	27	(	(	PUNCT
dti-1548	72	28	h2	h2	NOUN
dti-1548	72	29	)	)	PUNCT
dti-1548	72	30	and	and	CCONJ
dti-1548	72	31	hypoxanthine	hypoxanthine	NOUN
dti-1548	72	32	phosphoribosyl	phosphoribosyl	PROPN
dti-1548	72	33	transferase	transferase	NOUN
dti-1548	72	34	1	1	NUM
dti-1548	72	35	(	(	PUNCT
dti-1548	72	36	hprt1	hprt1	NOUN
dti-1548	72	37	)	)	PUNCT
dti-1548	72	38	(	(	PUNCT
dti-1548	72	39	h4	h4	PROPN
dti-1548	72	40	)	)	PUNCT
dti-1548	72	41	.	.	PUNCT
dti-1548	73	1	fold	fold	ADJ
dti-1548	73	2	regulation	regulation	NOUN
dti-1548	73	3	values	value	NOUN
dti-1548	73	4	for	for	ADP
dti-1548	73	5	each	each	PRON
dti-1548	73	6	of	of	ADP
dti-1548	73	7	the	the	DET
dti-1548	73	8	84	84	NUM
dti-1548	73	9	genes	gene	NOUN
dti-1548	73	10	in	in	ADP
dti-1548	73	11	hcc	hcc	PROPN
dti-1548	73	12	cases	case	NOUN
dti-1548	73	13	was	be	AUX
dti-1548	73	14	determined	determine	VERB
dti-1548	73	15	by	by	ADP
dti-1548	73	16	the	the	DET
dti-1548	73	17	qiagen	qiagen	PROPN
dti-1548	73	18	online	online	PROPN
dti-1548	73	19	data	data	PROPN
dti-1548	73	20	analysis	analysis	NOUN
dti-1548	73	21	webportal	webportal	NOUN
dti-1548	73	22	(	(	PUNCT
dti-1548	73	23	at	at	ADP
dti-1548	73	24	www.sabiosciences.com/pcrarraydataanalysis	www.sabiosciences.com/pcrarraydataanalysis	PROPN
dti-1548	73	25	.	.	PUNCT
dti-1548	74	1	php	php	PROPN
dti-1548	74	2	)	)	PUNCT
dti-1548	74	3	.	.	PUNCT
dti-1548	75	1	then	then	ADV
dti-1548	75	2	for	for	ADP
dti-1548	75	3	each	each	DET
dti-1548	75	4	gene	gene	NOUN
dti-1548	75	5	the	the	DET
dti-1548	75	6	percentages	percentage	NOUN
dti-1548	75	7	of	of	ADP
dti-1548	75	8	cases	case	NOUN
dti-1548	75	9	showing	show	VERB
dti-1548	75	10	upregulation	upregulation	NOUN
dti-1548	75	11	,	,	PUNCT
dti-1548	75	12	normal	normal	ADJ
dti-1548	75	13	expression	expression	NOUN
dti-1548	75	14	,	,	PUNCT
dti-1548	75	15	and	and	CCONJ
dti-1548	75	16	downregulation	downregulation	NOUN
dti-1548	75	17	were	be	AUX
dti-1548	75	18	determined	determine	VERB
dti-1548	75	19	.	.	PUNCT
dti-1548	76	1	determination	determination	NOUN
dti-1548	76	2	of	of	ADP
dti-1548	76	3	the	the	DET
dti-1548	76	4	significantly	significantly	ADJ
dti-1548	76	5	upand	upand	NOUN
dti-1548	76	6	downregulated	downregulate	VERB
dti-1548	76	7	genes	gene	NOUN
dti-1548	76	8	in	in	ADP
dti-1548	76	9	hcc	hcc	PROPN
dti-1548	76	10	cases	case	NOUN
dti-1548	76	11	using	use	VERB
dti-1548	76	12	spss	spss	PROPN
dti-1548	76	13	statistics	statistics	PROPN
dti-1548	76	14	software	software	PROPN
dti-1548	76	15	version	version	PROPN
dti-1548	76	16	20.0	20.0	NUM
dti-1548	76	17	was	be	AUX
dti-1548	76	18	carried	carry	VERB
dti-1548	76	19	out	out	ADP
dti-1548	76	20	using	use	VERB
dti-1548	76	21	nonparametric	nonparametric	NOUN
dti-1548	76	22	mannwhitney	mannwhitney	ADJ
dti-1548	76	23	test	test	NOUN
dti-1548	76	24	.	.	PUNCT
dti-1548	77	1	the	the	DET
dti-1548	77	2	most	most	ADV
dti-1548	77	3	frequently	frequently	ADV
dti-1548	77	4	coregulated	coregulate	VERB
dti-1548	77	5	genes	gene	NOUN
dti-1548	77	6	were	be	AUX
dti-1548	77	7	identified	identify	VERB
dti-1548	77	8	.	.	PUNCT
dti-1548	78	1	identification	identification	NOUN
dti-1548	78	2	of	of	ADP
dti-1548	78	3	genes	gene	NOUN
dti-1548	78	4	significantly	significantly	ADV
dti-1548	78	5	correlated	correlate	VERB
dti-1548	78	6	with	with	ADP
dti-1548	78	7	the	the	DET
dti-1548	78	8	different	different	ADJ
dti-1548	78	9	patient	patient	NOUN
dti-1548	78	10	/	/	SYM
dti-1548	78	11	tumor	tumor	NOUN
dti-1548	78	12	characteristics	characteristic	NOUN
dti-1548	78	13	carried	carry	VERB
dti-1548	78	14	out	out	ADP
dti-1548	78	15	using	use	VERB
dti-1548	78	16	the	the	DET
dti-1548	78	17	mann	mann	PROPN
dti-1548	78	18	-	-	PUNCT
dti-1548	78	19	whitney	whitney	PROPN
dti-1548	78	20	test	test	NOUN
dti-1548	78	21	.	.	PUNCT
dti-1548	79	1	finally	finally	ADV
dti-1548	79	2	,	,	PUNCT
dti-1548	79	3	active	active	ADJ
dti-1548	79	4	and	and	CCONJ
dti-1548	79	5	inactive	inactive	ADJ
dti-1548	79	6	pathways	pathway	NOUN
dti-1548	79	7	in	in	ADP
dti-1548	79	8	hcc	hcc	PROPN
dti-1548	79	9	from	from	ADP
dti-1548	79	10	the	the	DET
dti-1548	79	11	present	present	ADJ
dti-1548	79	12	dataset	dataset	NOUN
dti-1548	79	13	were	be	AUX
dti-1548	79	14	identified	identify	VERB
dti-1548	79	15	;	;	PUNCT
dti-1548	79	16	an	an	DET
dti-1548	79	17	excel	excel	NOUN
dti-1548	79	18	file	file	NOUN
dti-1548	79	19	containing	contain	VERB
dti-1548	79	20	the	the	DET
dti-1548	79	21	gene	gene	NOUN
dti-1548	79	22	symbols	symbol	NOUN
dti-1548	79	23	,	,	PUNCT
dti-1548	79	24	fold	fold	ADJ
dti-1548	79	25	regulation	regulation	NOUN
dti-1548	79	26	values	value	NOUN
dti-1548	79	27	,	,	PUNCT
dti-1548	79	28	and	and	CCONJ
dti-1548	79	29	the	the	DET
dti-1548	79	30	p	p	NOUN
dti-1548	79	31	values	value	NOUN
dti-1548	79	32	for	for	ADP
dti-1548	79	33	all	all	DET
dti-1548	79	34	84	84	NUM
dti-1548	79	35	tested	test	VERB
dti-1548	79	36	genes	gene	NOUN
dti-1548	79	37	was	be	AUX
dti-1548	79	38	uploaded	upload	VERB
dti-1548	79	39	to	to	ADP
dti-1548	79	40	the	the	DET
dti-1548	79	41	ingenuity	ingenuity	NOUN
dti-1548	79	42	pathway	pathway	NOUN
dti-1548	79	43	analysis	analysis	NOUN
dti-1548	79	44	(	(	PUNCT
dti-1548	79	45	ipa	ipa	PROPN
dti-1548	79	46	)	)	PUNCT
dti-1548	79	47	software	software	NOUN
dti-1548	79	48	.	.	PUNCT
dti-1548	80	1	results	result	VERB
dti-1548	80	2	the	the	DET
dti-1548	80	3	demographic	demographic	ADJ
dti-1548	80	4	data	datum	NOUN
dti-1548	80	5	of	of	ADP
dti-1548	80	6	the	the	DET
dti-1548	80	7	cases	case	NOUN
dti-1548	80	8	included	include	VERB
dti-1548	80	9	are	be	AUX
dti-1548	80	10	presented	present	VERB
dti-1548	80	11	in	in	ADP
dti-1548	80	12	table	table	NOUN
dti-1548	80	13	i.	i.	NOUN
dti-1548	80	14	gross	gross	ADJ
dti-1548	80	15	pathological	pathological	ADJ
dti-1548	80	16	examination	examination	NOUN
dti-1548	80	17	of	of	ADP
dti-1548	80	18	hcc	hcc	PROPN
dti-1548	80	19	tumors	tumor	NOUN
dti-1548	80	20	tumor	tumor	NOUN
dti-1548	80	21	size	size	NOUN
dti-1548	80	22	ranged	range	VERB
dti-1548	80	23	from	from	ADP
dti-1548	80	24	1.75	1.75	NUM
dti-1548	80	25	to	to	ADP
dti-1548	80	26	16.0	16.0	NUM
dti-1548	80	27	cm	cm	NOUN
dti-1548	80	28	,	,	PUNCT
dti-1548	80	29	with	with	ADP
dti-1548	80	30	a	a	DET
dti-1548	80	31	median	median	NOUN
dti-1548	80	32	of	of	ADP
dti-1548	80	33	4.8	4.8	NUM
dti-1548	80	34	cm	cm	NOUN
dti-1548	80	35	and	and	CCONJ
dti-1548	80	36	a	a	DET
dti-1548	80	37	mean	mean	NOUN
dti-1548	80	38	of	of	ADP
dti-1548	80	39	5.38	5.38	NUM
dti-1548	80	40	±	±	NUM
dti-1548	81	1	3.46	3.46	NUM
dti-1548	81	2	cm	cm	NOUN
dti-1548	81	3	standard	standard	ADJ
dti-1548	81	4	deviation	deviation	NOUN
dti-1548	81	5	(	(	PUNCT
dti-1548	81	6	sd	sd	NOUN
dti-1548	81	7	;	;	PUNCT
dti-1548	81	8	tab	tab	PROPN
dti-1548	81	9	.	.	PUNCT
dti-1548	81	10	ii	ii	PROPN
dti-1548	81	11	)	)	PUNCT
dti-1548	81	12	.	.	PUNCT
dti-1548	82	1	microscopic	microscopic	ADJ
dti-1548	82	2	examination	examination	NOUN
dti-1548	82	3	of	of	ADP
dti-1548	82	4	hcc	hcc	PROPN
dti-1548	82	5	tumors	tumor	NOUN
dti-1548	82	6	the	the	DET
dti-1548	82	7	most	most	ADV
dti-1548	82	8	frequently	frequently	ADV
dti-1548	82	9	encountered	encounter	VERB
dti-1548	82	10	histologic	histologic	ADJ
dti-1548	82	11	patterns	pattern	NOUN
dti-1548	82	12	are	be	AUX
dti-1548	82	13	displayed	display	VERB
dti-1548	82	14	in	in	ADP
dti-1548	82	15	table	table	NOUN
dti-1548	82	16	iii	iii	PROPN
dti-1548	82	17	.	.	PUNCT
dti-1548	83	1	twenty	twenty	NUM
dti-1548	83	2	-	-	PUNCT
dti-1548	83	3	six	six	NUM
dti-1548	83	4	out	out	ADP
dti-1548	83	5	of	of	ADP
dti-1548	83	6	32	32	NUM
dti-1548	83	7	cases	case	NOUN
dti-1548	83	8	showed	show	VERB
dti-1548	83	9	combined	combined	ADJ
dti-1548	83	10	histological	histological	ADJ
dti-1548	83	11	patterns	pattern	NOUN
dti-1548	83	12	in	in	ADP
dti-1548	83	13	the	the	DET
dti-1548	83	14	following	follow	VERB
dti-1548	83	15	frequencies	frequency	NOUN
dti-1548	83	16	(	(	PUNCT
dti-1548	83	17	tab	tab	NOUN
dti-1548	83	18	.	.	PUNCT
dti-1548	83	19	iv	iv	NUM
dti-1548	83	20	)	)	PUNCT
dti-1548	83	21	.	.	PUNCT
dti-1548	84	1	frequency	frequency	NOUN
dti-1548	84	2	of	of	ADP
dti-1548	84	3	different	different	ADJ
dti-1548	84	4	histopathological	histopathological	ADJ
dti-1548	84	5	features	feature	NOUN
dti-1548	84	6	of	of	ADP
dti-1548	84	7	hcc	hcc	PROPN
dti-1548	84	8	tumors	tumor	NOUN
dti-1548	84	9	including	include	VERB
dti-1548	84	10	edmonson	edmonson	NOUN
dti-1548	84	11	and	and	CCONJ
dti-1548	84	12	steiner	steiner	PROPN
dti-1548	84	13	tumor	tumor	NOUN
dti-1548	84	14	grades	grade	NOUN
dti-1548	84	15	is	be	AUX
dti-1548	84	16	shown	show	VERB
dti-1548	84	17	in	in	ADP
dti-1548	84	18	tables	table	NOUN
dti-1548	84	19	v	v	ADP
dti-1548	84	20	and	and	CCONJ
dti-1548	84	21	vi	vi	NOUN
dti-1548	84	22	,	,	PUNCT
dti-1548	84	23	respectively	respectively	ADV
dti-1548	84	24	.	.	PUNCT
dti-1548	85	1	frequency	frequency	NOUN
dti-1548	85	2	of	of	ADP
dti-1548	85	3	ptnm	ptnm	PROPN
dti-1548	85	4	tumor	tumor	NOUN
dti-1548	85	5	stages	stage	NOUN
dti-1548	85	6	is	be	AUX
dti-1548	85	7	shown	show	VERB
dti-1548	85	8	in	in	ADP
dti-1548	85	9	table	table	NOUN
dti-1548	85	10	vii	vii	PROPN
dti-1548	85	11	.	.	PROPN
dti-1548	85	12	table	table	NOUN
dti-1548	86	1	i	i	PRON
dti-1548	86	2	distribution	distribution	NOUN
dti-1548	86	3	of	of	ADP
dti-1548	86	4	the	the	DET
dti-1548	86	5	studied	study	VERB
dti-1548	86	6	cases	case	NOUN
dti-1548	86	7	according	accord	VERB
dti-1548	86	8	to	to	ADP
dti-1548	86	9	demographic	demographic	ADJ
dti-1548	86	10	data	datum	NOUN
dti-1548	86	11	(	(	PUNCT
dti-1548	86	12	n	n	NOUN
dti-1548	86	13	=	=	SYM
dti-1548	86	14	32	32	NUM
dti-1548	86	15	)	)	PUNCT
dti-1548	86	16	number	number	NOUN
dti-1548	86	17	%	%	NOUN
dti-1548	86	18	gender	gender	NOUN
dti-1548	86	19	male	male	NOUN
dti-1548	86	20	24	24	NUM
dti-1548	86	21	75.0	75.0	NUM
dti-1548	86	22	female	female	ADJ
dti-1548	86	23	8	8	NUM
dti-1548	86	24	25.0	25.0	NUM
dti-1548	86	25	age	age	NOUN
dti-1548	86	26	(	(	PUNCT
dti-1548	86	27	years	year	NOUN
dti-1548	86	28	)	)	PUNCT
dti-1548	86	29	≤60	≤60	PROPN
dti-1548	86	30	22	22	NUM
dti-1548	86	31	68.8	68.8	NUM
dti-1548	86	32	>	>	SYM
dti-1548	86	33	60	60	NUM
dti-1548	86	34	10	10	NUM
dti-1548	86	35	31.3	31.3	NUM
dti-1548	86	36	min.–max	min.–max	NOUN
dti-1548	86	37	.	.	PUNCT
dti-1548	87	1	47.0–67.0	47.0–67.0	NUM
dti-1548	87	2	mean	mean	NOUN
dti-1548	87	3	±	±	NUM
dti-1548	87	4	standard	standard	ADJ
dti-1548	87	5	deviation	deviation	NOUN
dti-1548	87	6	56.06	56.06	NUM
dti-1548	87	7	±	±	NUM
dti-1548	87	8	5.49	5.49	NUM
dti-1548	87	9	median	median	NOUN
dti-1548	87	10	56.0	56.0	NUM
dti-1548	87	11	comorbidities	comorbiditie	NOUN
dti-1548	87	12	17/25	17/25	NUM
dti-1548	87	13	53.1	53.1	NUM
dti-1548	87	14	alfa	alfa	NOUN
dti-1548	87	15	-	-	PUNCT
dti-1548	87	16	fetoprotein	fetoprotein	PROPN
dti-1548	87	17	(	(	PUNCT
dti-1548	87	18	≥200	≥200	ADJ
dti-1548	87	19	ng	ng	PROPN
dti-1548	87	20	/	/	SYM
dti-1548	87	21	ml	ml	NOUN
dti-1548	87	22	)	)	PUNCT
dti-1548	87	23	8/25	8/25	NUM
dti-1548	87	24	25.0	25.0	NUM
dti-1548	87	25	table	table	NOUN
dti-1548	87	26	ii	ii	NOUN
dti-1548	87	27	the	the	DET
dti-1548	87	28	frequency	frequency	NOUN
dti-1548	87	29	of	of	ADP
dti-1548	87	30	the	the	DET
dti-1548	87	31	gross	gross	ADJ
dti-1548	87	32	characteristics	characteristic	NOUN
dti-1548	87	33	of	of	ADP
dti-1548	87	34	the	the	DET
dti-1548	87	35	tumors	tumor	NOUN
dti-1548	87	36	included	include	VERB
dti-1548	87	37	in	in	ADP
dti-1548	87	38	the	the	DET
dti-1548	87	39	present	present	ADJ
dti-1548	87	40	study	study	NOUN
dti-1548	87	41	gross	gross	ADJ
dti-1548	87	42	findings	finding	NOUN
dti-1548	87	43	number	number	NOUN
dti-1548	87	44	%	%	NOUN
dti-1548	87	45	gross	gross	ADJ
dti-1548	87	46	capsulation	capsulation	NOUN
dti-1548	87	47	(	(	PUNCT
dti-1548	87	48	n	n	NOUN
dti-1548	87	49	=	=	SYM
dti-1548	87	50	32	32	NUM
dti-1548	87	51	)	)	PUNCT
dti-1548	87	52	absent	absent	ADJ
dti-1548	87	53	present	present	ADJ
dti-1548	87	54	6	6	NUM
dti-1548	87	55	26	26	NUM
dti-1548	87	56	18.8	18.8	NUM
dti-1548	87	57	81.3	81.3	NUM
dti-1548	87	58	gross	gross	ADJ
dti-1548	87	59	necrosis	necrosis	NOUN
dti-1548	87	60	(	(	PUNCT
dti-1548	87	61	n	n	NOUN
dti-1548	87	62	=	=	SYM
dti-1548	87	63	32	32	NUM
dti-1548	87	64	)	)	PUNCT
dti-1548	87	65	absent	absent	ADJ
dti-1548	87	66	present	present	ADJ
dti-1548	87	67	21	21	NUM
dti-1548	87	68	11	11	NUM
dti-1548	87	69	65.6	65.6	NUM
dti-1548	87	70	34.4	34.4	NUM
dti-1548	87	71	multifocality	multifocality	NOUN
dti-1548	87	72	(	(	PUNCT
dti-1548	87	73	n	n	NOUN
dti-1548	87	74	=	=	SYM
dti-1548	87	75	32	32	NUM
dti-1548	87	76	)	)	PUNCT
dti-1548	87	77	absent	absent	ADJ
dti-1548	87	78	present	present	ADJ
dti-1548	87	79	4	4	NUM
dti-1548	87	80	28	28	NUM
dti-1548	87	81	12.5	12.5	NUM
dti-1548	87	82	87.5	87.5	NUM
dti-1548	87	83	satellites	satellite	NOUN
dti-1548	87	84	(	(	PUNCT
dti-1548	87	85	n	n	NOUN
dti-1548	87	86	=	=	SYM
dti-1548	87	87	32	32	NUM
dti-1548	87	88	)	)	PUNCT
dti-1548	87	89	absent	absent	ADJ
dti-1548	87	90	present	present	ADJ
dti-1548	87	91	6	6	NUM
dti-1548	87	92	26	26	NUM
dti-1548	87	93	18.8	18.8	NUM
dti-1548	87	94	81.3	81.3	NUM
dti-1548	87	95	bile	bile	NOUN
dti-1548	87	96	production	production	NOUN
dti-1548	87	97	(	(	PUNCT
dti-1548	87	98	n	n	NOUN
dti-1548	87	99	=	=	SYM
dti-1548	87	100	32	32	NUM
dti-1548	87	101	)	)	PUNCT
dti-1548	87	102	absent	absent	ADJ
dti-1548	87	103	present	present	ADJ
dti-1548	87	104	15	15	NUM
dti-1548	87	105	17	17	NUM
dti-1548	87	106	46.9	46.9	NUM
dti-1548	87	107	53.1	53.1	NUM
dti-1548	87	108	table	table	NOUN
dti-1548	87	109	iii	iii	NOUN
dti-1548	87	110	the	the	DET
dti-1548	87	111	frequency	frequency	NOUN
dti-1548	87	112	of	of	ADP
dti-1548	87	113	the	the	DET
dti-1548	87	114	different	different	ADJ
dti-1548	87	115	histologic	histologic	NOUN
dti-1548	87	116	patterns	pattern	NOUN
dti-1548	87	117	of	of	ADP
dti-1548	87	118	the	the	DET
dti-1548	87	119	hcc	hcc	PROPN
dti-1548	87	120	cases	case	NOUN
dti-1548	87	121	included	include	VERB
dti-1548	87	122	in	in	ADP
dti-1548	87	123	the	the	DET
dti-1548	87	124	present	present	ADJ
dti-1548	87	125	study	study	NOUN
dti-1548	87	126	histologic	histologic	NOUN
dti-1548	87	127	pattern	pattern	NOUN
dti-1548	87	128	of	of	ADP
dti-1548	87	129	hcc	hcc	PROPN
dti-1548	87	130	(	(	PUNCT
dti-1548	87	131	n	n	NOUN
dti-1548	87	132	=	=	SYM
dti-1548	87	133	32	32	NUM
dti-1548	87	134	)	)	PUNCT
dti-1548	87	135	number	number	NOUN
dti-1548	87	136	%	%	NOUN
dti-1548	87	137	trabecular	trabecular	NOUN
dti-1548	87	138	absent	absent	ADJ
dti-1548	87	139	3	3	NUM
dti-1548	87	140	9.4	9.4	NUM
dti-1548	87	141	present	present	ADJ
dti-1548	87	142	29	29	NUM
dti-1548	87	143	90.6	90.6	NUM
dti-1548	87	144	pseudoglandular	pseudoglandular	NOUN
dti-1548	87	145	absent	absent	ADJ
dti-1548	87	146	12	12	NUM
dti-1548	87	147	37.5	37.5	NUM
dti-1548	87	148	present	present	ADJ
dti-1548	87	149	20	20	NUM
dti-1548	87	150	62.5	62.5	NUM
dti-1548	87	151	compact	compact	ADJ
dti-1548	87	152	absent	absent	ADJ
dti-1548	87	153	20	20	NUM
dti-1548	87	154	62.5	62.5	NUM
dti-1548	87	155	present	present	ADJ
dti-1548	87	156	12	12	NUM
dti-1548	87	157	37.5	37.5	NUM
dti-1548	87	158	hcc	hcc	NOUN
dti-1548	87	159	=	=	NOUN
dti-1548	87	160	hepatocellular	hepatocellular	ADJ
dti-1548	87	161	carcinoma	carcinoma	NOUN
dti-1548	87	162	.	.	PUNCT
dti-1548	88	1	possible	possible	ADJ
dti-1548	88	2	therapeutic	therapeutic	ADJ
dti-1548	88	3	targets	target	NOUN
dti-1548	88	4	in	in	ADP
dti-1548	88	5	igf1r	igf1r	ADJ
dti-1548	88	6	pathway	pathway	NOUN
dti-1548	88	7	in	in	ADP
dti-1548	88	8	egyptian	egyptian	PROPN
dti-1548	88	9	hcv	hcv	X
dti-1548	88	10	related	relate	VERB
dti-1548	88	11	hcc4	hcc4	PROPN
dti-1548	88	12	©	©	PROPN
dti-1548	88	13	2020	2020	NUM
dti-1548	88	14	the	the	DET
dti-1548	88	15	authors	author	NOUN
dti-1548	88	16	.	.	PUNCT
dti-1548	89	1	published	publish	VERB
dti-1548	89	2	by	by	ADP
dti-1548	89	3	aboutscience	aboutscience	NOUN
dti-1548	89	4	significantly	significantly	ADV
dti-1548	89	5	upand	upand	PROPN
dti-1548	89	6	downregulated	downregulate	VERB
dti-1548	89	7	genes	gene	NOUN
dti-1548	89	8	a	a	DET
dti-1548	89	9	total	total	NOUN
dti-1548	89	10	of	of	ADP
dti-1548	89	11	51	51	NUM
dti-1548	89	12	deregulated	deregulated	ADJ
dti-1548	89	13	genes	gene	NOUN
dti-1548	89	14	were	be	AUX
dti-1548	89	15	found	find	VERB
dti-1548	89	16	in	in	ADP
dti-1548	89	17	the	the	DET
dti-1548	89	18	present	present	ADJ
dti-1548	89	19	cohort	cohort	NOUN
dti-1548	89	20	of	of	ADP
dti-1548	89	21	hccs	hccs	NOUN
dti-1548	89	22	.	.	PUNCT
dti-1548	90	1	fourteen	fourteen	NUM
dti-1548	90	2	genes	gene	NOUN
dti-1548	90	3	were	be	AUX
dti-1548	90	4	upregulated	upregulate	VERB
dti-1548	90	5	while	while	SCONJ
dti-1548	90	6	37	37	NUM
dti-1548	90	7	genes	gene	NOUN
dti-1548	90	8	were	be	AUX
dti-1548	90	9	downregulated	downregulate	VERB
dti-1548	90	10	.	.	PUNCT
dti-1548	91	1	statistically	statistically	ADV
dti-1548	91	2	significant	significant	ADJ
dti-1548	91	3	upregulation	upregulation	NOUN
dti-1548	91	4	was	be	AUX
dti-1548	91	5	observed	observe	VERB
dti-1548	91	6	in	in	ADP
dti-1548	91	7	hcc	hcc	PROPN
dti-1548	91	8	patients	patient	NOUN
dti-1548	91	9	,	,	PUNCT
dti-1548	91	10	in	in	ADP
dti-1548	91	11	comparison	comparison	NOUN
dti-1548	91	12	to	to	ADP
dti-1548	91	13	the	the	DET
dti-1548	91	14	control	control	NOUN
dti-1548	91	15	group	group	NOUN
dti-1548	91	16	,	,	PUNCT
dti-1548	91	17	in	in	ADP
dti-1548	91	18	six	six	NUM
dti-1548	91	19	genes	gene	NOUN
dti-1548	91	20	,	,	PUNCT
dti-1548	91	21	namely	namely	ADV
dti-1548	91	22	aebp1	aebp1	PROPN
dti-1548	91	23	,	,	PUNCT
dti-1548	91	24	akt2	akt2	PROPN
dti-1548	91	25	,	,	PUNCT
dti-1548	91	26	fos	fos	INTJ
dti-1548	91	27	,	,	PUNCT
dti-1548	91	28	pik3r1	pik3r1	ADJ
dti-1548	91	29	,	,	PUNCT
dti-1548	91	30	prkci	prkci	ADJ
dti-1548	91	31	,	,	PUNCT
dti-1548	91	32	shc1	shc1	PROPN
dti-1548	91	33	,	,	PUNCT
dti-1548	91	34	where	where	SCONJ
dti-1548	91	35	shc1	shc1	PROPN
dti-1548	91	36	was	be	AUX
dti-1548	91	37	the	the	DET
dti-1548	91	38	most	most	ADV
dti-1548	91	39	significantly	significantly	ADV
dti-1548	91	40	overexpressed	overexpresse	VERB
dti-1548	91	41	gene	gene	NOUN
dti-1548	91	42	(	(	PUNCT
dti-1548	91	43	p	p	NOUN
dti-1548	91	44	value	value	NOUN
dti-1548	91	45	:	:	PUNCT
dti-1548	91	46	0.001	0.001	NUM
dti-1548	91	47	)	)	PUNCT
dti-1548	91	48	(	(	PUNCT
dti-1548	91	49	tab	tab	NOUN
dti-1548	91	50	.	.	PUNCT
dti-1548	92	1	viii	viii	PROPN
dti-1548	92	2	,	,	PUNCT
dti-1548	92	3	fig	fig	NOUN
dti-1548	92	4	.	.	NOUN
dti-1548	92	5	1	1	NUM
dti-1548	92	6	)	)	PUNCT
dti-1548	92	7	.	.	PUNCT
dti-1548	93	1	shc1	shc1	PROPN
dti-1548	93	2	,	,	PUNCT
dti-1548	93	3	aebp1	aebp1	PROPN
dti-1548	93	4	,	,	PUNCT
dti-1548	93	5	akt2	akt2	PROPN
dti-1548	93	6	,	,	PUNCT
dti-1548	93	7	and	and	CCONJ
dti-1548	93	8	pkci	pkci	NOUN
dti-1548	93	9	were	be	AUX
dti-1548	93	10	the	the	DET
dti-1548	93	11	most	most	ADV
dti-1548	93	12	frequently	frequently	ADV
dti-1548	93	13	coregulated	coregulate	VERB
dti-1548	93	14	genes	gene	NOUN
dti-1548	93	15	among	among	ADP
dti-1548	93	16	the	the	DET
dti-1548	93	17	significantly	significantly	ADV
dti-1548	93	18	upregulated	upregulated	ADJ
dti-1548	93	19	genes	gene	NOUN
dti-1548	93	20	.	.	PUNCT
dti-1548	94	1	on	on	ADP
dti-1548	94	2	the	the	DET
dti-1548	94	3	other	other	ADJ
dti-1548	94	4	hand	hand	NOUN
dti-1548	94	5	,	,	PUNCT
dti-1548	94	6	the	the	DET
dti-1548	94	7	frequency	frequency	NOUN
dti-1548	94	8	and	and	CCONJ
dti-1548	94	9	magnitude	magnitude	NOUN
dti-1548	94	10	of	of	ADP
dti-1548	94	11	the	the	DET
dti-1548	94	12	downregulation	downregulation	NOUN
dti-1548	94	13	events	event	NOUN
dti-1548	94	14	were	be	AUX
dti-1548	94	15	greater	great	ADJ
dti-1548	94	16	than	than	ADP
dti-1548	94	17	that	that	PRON
dti-1548	94	18	of	of	ADP
dti-1548	94	19	upregulation	upregulation	NOUN
dti-1548	94	20	events	event	NOUN
dti-1548	94	21	(	(	PUNCT
dti-1548	94	22	tabs	tab	NOUN
dti-1548	94	23	.	.	PUNCT
dti-1548	95	1	viii	viii	PROPN
dti-1548	95	2	and	and	CCONJ
dti-1548	95	3	ix	ix	ADJ
dti-1548	95	4	)	)	PUNCT
dti-1548	95	5	.	.	PUNCT
dti-1548	96	1	thirteen	thirteen	NUM
dti-1548	96	2	genes	gene	NOUN
dti-1548	96	3	,	,	PUNCT
dti-1548	96	4	namely	namely	ADV
dti-1548	96	5	adrb3	adrb3	ADJ
dti-1548	96	6	,	,	PUNCT
dti-1548	96	7	cebpa	cebpa	NOUN
dti-1548	96	8	,	,	PUNCT
dti-1548	96	9	dusp14	dusp14	NOUN
dti-1548	96	10	,	,	PUNCT
dti-1548	96	11	ercc1	ercc1	PROPN
dti-1548	96	12	,	,	PUNCT
dti-1548	96	13	frs3	frs3	PROPN
dti-1548	96	14	,	,	PUNCT
dti-1548	96	15	igf2	igf2	PROPN
dti-1548	96	16	,	,	PUNCT
dti-1548	96	17	ins	ins	PROPN
dti-1548	96	18	,	,	PUNCT
dti-1548	96	19	irs1	irs1	PROPN
dti-1548	96	20	,	,	PUNCT
dti-1548	96	21	jun	jun	PROPN
dti-1548	96	22	,	,	PUNCT
dti-1548	96	23	mtor	mtor	PROPN
dti-1548	96	24	,	,	PUNCT
dti-1548	96	25	pik3r2	pik3r2	ADV
dti-1548	96	26	,	,	PUNCT
dti-1548	96	27	ppp1ca	ppp1ca	NOUN
dti-1548	96	28	,	,	PUNCT
dti-1548	96	29	and	and	CCONJ
dti-1548	96	30	rps6ka1	rps6ka1	PROPN
dti-1548	96	31	,	,	PUNCT
dti-1548	96	32	were	be	AUX
dti-1548	96	33	significantly	significantly	ADV
dti-1548	96	34	underexpressed	underexpressed	ADJ
dti-1548	96	35	in	in	ADP
dti-1548	96	36	hcc	hcc	PROPN
dti-1548	96	37	patients	patient	NOUN
dti-1548	96	38	relative	relative	ADJ
dti-1548	96	39	to	to	ADP
dti-1548	96	40	the	the	DET
dti-1548	96	41	control	control	NOUN
dti-1548	96	42	group	group	NOUN
dti-1548	96	43	,	,	PUNCT
dti-1548	96	44	where	where	SCONJ
dti-1548	96	45	ppp1ca	ppp1ca	NOUN
dti-1548	96	46	and	and	CCONJ
dti-1548	96	47	ins	in	NOUN
dti-1548	96	48	were	be	AUX
dti-1548	96	49	the	the	DET
dti-1548	96	50	two	two	NUM
dti-1548	96	51	most	most	ADV
dti-1548	96	52	significantly	significantly	ADV
dti-1548	96	53	underexpressed	underexpressed	ADJ
dti-1548	96	54	genes	gene	NOUN
dti-1548	96	55	(	(	PUNCT
dti-1548	96	56	p	p	NOUN
dti-1548	96	57	value	value	NOUN
dti-1548	96	58	:	:	PUNCT
dti-1548	96	59	0.002	0.002	NUM
dti-1548	96	60	)	)	PUNCT
dti-1548	96	61	(	(	PUNCT
dti-1548	96	62	tab	tab	NOUN
dti-1548	96	63	.	.	PUNCT
dti-1548	97	1	ix	ix	PROPN
dti-1548	97	2	,	,	PUNCT
dti-1548	97	3	fig	fig	NOUN
dti-1548	97	4	.	.	PUNCT
dti-1548	97	5	1	1	NUM
dti-1548	97	6	)	)	PUNCT
dti-1548	97	7	.	.	PUNCT
dti-1548	98	1	ins	in	NOUN
dti-1548	98	2	and	and	CCONJ
dti-1548	98	3	ppp1ca	ppp1ca	NOUN
dti-1548	98	4	were	be	AUX
dti-1548	98	5	the	the	DET
dti-1548	98	6	most	most	ADV
dti-1548	98	7	frequently	frequently	ADV
dti-1548	98	8	coregulated	coregulate	VERB
dti-1548	98	9	genes	gene	NOUN
dti-1548	98	10	among	among	ADP
dti-1548	98	11	the	the	DET
dti-1548	98	12	significantly	significantly	ADV
dti-1548	98	13	downregulated	downregulate	VERB
dti-1548	98	14	genes	gene	NOUN
dti-1548	98	15	.	.	PUNCT
dti-1548	99	1	table	table	NOUN
dti-1548	99	2	iv	iv	ADP
dti-1548	99	3	the	the	DET
dti-1548	99	4	frequency	frequency	NOUN
dti-1548	99	5	of	of	ADP
dti-1548	99	6	different	different	ADJ
dti-1548	99	7	combinations	combination	NOUN
dti-1548	99	8	of	of	ADP
dti-1548	99	9	patterns	pattern	NOUN
dti-1548	99	10	in	in	ADP
dti-1548	99	11	the	the	DET
dti-1548	99	12	tumors	tumor	NOUN
dti-1548	99	13	included	include	VERB
dti-1548	99	14	in	in	ADP
dti-1548	99	15	the	the	DET
dti-1548	99	16	present	present	ADJ
dti-1548	99	17	study	study	NOUN
dti-1548	99	18	hccs	hccs	NOUN
dti-1548	99	19	with	with	ADP
dti-1548	99	20	combined	combine	VERB
dti-1548	99	21	histologic	histologic	ADJ
dti-1548	99	22	pattern	pattern	NOUN
dti-1548	99	23	number	number	NOUN
dti-1548	99	24	(	(	PUNCT
dti-1548	99	25	%	%	NOUN
dti-1548	99	26	)	)	PUNCT
dti-1548	99	27	trabecular	trabecular	ADJ
dti-1548	99	28	and	and	CCONJ
dti-1548	99	29	pseudoglandular	pseudoglandular	ADJ
dti-1548	99	30	trabecular	trabecular	ADJ
dti-1548	99	31	and	and	CCONJ
dti-1548	99	32	compact	compact	ADJ
dti-1548	99	33	trabecular	trabecular	ADJ
dti-1548	99	34	,	,	PUNCT
dti-1548	99	35	pseudoglandular	pseudoglandular	ADJ
dti-1548	99	36	,	,	PUNCT
dti-1548	99	37	and	and	CCONJ
dti-1548	99	38	compact	compact	ADJ
dti-1548	99	39	glandular	glandular	ADJ
dti-1548	99	40	and	and	CCONJ
dti-1548	99	41	compact	compact	ADJ
dti-1548	99	42	15	15	NUM
dti-1548	99	43	6	6	NUM
dti-1548	99	44	3	3	NUM
dti-1548	99	45	2	2	NUM
dti-1548	99	46	total	total	NOUN
dti-1548	99	47	26	26	NUM
dti-1548	99	48	hcc	hcc	NOUN
dti-1548	99	49	=	=	NOUN
dti-1548	99	50	hepatocellular	hepatocellular	ADJ
dti-1548	99	51	carcinoma	carcinoma	NOUN
dti-1548	99	52	.	.	PUNCT
dti-1548	100	1	table	table	NOUN
dti-1548	100	2	v	v	ADP
dti-1548	100	3	the	the	DET
dti-1548	100	4	frequency	frequency	NOUN
dti-1548	100	5	of	of	ADP
dti-1548	100	6	giant	giant	ADJ
dti-1548	100	7	cells	cell	NOUN
dti-1548	100	8	,	,	PUNCT
dti-1548	100	9	clear	clear	ADJ
dti-1548	100	10	cells	cell	NOUN
dti-1548	100	11	,	,	PUNCT
dti-1548	100	12	vascular	vascular	ADJ
dti-1548	100	13	invasion	invasion	NOUN
dti-1548	100	14	,	,	PUNCT
dti-1548	100	15	and	and	CCONJ
dti-1548	100	16	dysplastic	dysplastic	ADJ
dti-1548	100	17	nodules	nodule	NOUN
dti-1548	100	18	in	in	ADP
dti-1548	100	19	the	the	DET
dti-1548	100	20	hcc	hcc	PROPN
dti-1548	100	21	cases	case	NOUN
dti-1548	100	22	included	include	VERB
dti-1548	100	23	in	in	ADP
dti-1548	100	24	the	the	DET
dti-1548	100	25	present	present	ADJ
dti-1548	100	26	study	study	NOUN
dti-1548	100	27	histologic	histologic	ADJ
dti-1548	100	28	feature	feature	NOUN
dti-1548	100	29	number	number	NOUN
dti-1548	100	30	%	%	NOUN
dti-1548	100	31	giant	giant	ADJ
dti-1548	100	32	cells	cell	NOUN
dti-1548	100	33	(	(	PUNCT
dti-1548	100	34	n	n	NOUN
dti-1548	100	35	=	=	SYM
dti-1548	100	36	32	32	NUM
dti-1548	100	37	)	)	PUNCT
dti-1548	100	38	absent	absent	VERB
dti-1548	100	39	17	17	NUM
dti-1548	100	40	53.1	53.1	NUM
dti-1548	100	41	present	present	ADJ
dti-1548	100	42	15	15	NUM
dti-1548	100	43	46.9	46.9	NUM
dti-1548	100	44	clear	clear	ADJ
dti-1548	100	45	cells	cell	NOUN
dti-1548	100	46	(	(	PUNCT
dti-1548	100	47	n	n	NOUN
dti-1548	100	48	=	=	SYM
dti-1548	100	49	32	32	NUM
dti-1548	100	50	)	)	PUNCT
dti-1548	100	51	absent	absent	VERB
dti-1548	100	52	17	17	NUM
dti-1548	100	53	53.1	53.1	NUM
dti-1548	100	54	present	present	ADJ
dti-1548	100	55	15	15	NUM
dti-1548	100	56	46.9	46.9	NUM
dti-1548	100	57	vascular	vascular	ADJ
dti-1548	100	58	invasion	invasion	NOUN
dti-1548	100	59	(	(	PUNCT
dti-1548	100	60	n	n	NOUN
dti-1548	100	61	=	=	SYM
dti-1548	100	62	32	32	NUM
dti-1548	100	63	)	)	PUNCT
dti-1548	100	64	absent	absent	VERB
dti-1548	100	65	11	11	NUM
dti-1548	100	66	34.4	34.4	NUM
dti-1548	100	67	present	present	NOUN
dti-1548	100	68	21	21	NUM
dti-1548	100	69	65.6	65.6	NUM
dti-1548	100	70	dysplastic	dysplastic	ADJ
dti-1548	100	71	nodules	nodule	NOUN
dti-1548	100	72	outside	outside	ADP
dti-1548	100	73	hcc	hcc	PROPN
dti-1548	100	74	(	(	PUNCT
dti-1548	100	75	n=	n=	ADJ
dti-1548	100	76	32	32	NUM
dti-1548	100	77	)	)	PUNCT
dti-1548	100	78	absent	absent	ADJ
dti-1548	100	79	13	13	NUM
dti-1548	100	80	40.6	40.6	NUM
dti-1548	100	81	present	present	ADJ
dti-1548	100	82	19	19	NUM
dti-1548	100	83	59.4	59.4	NUM
dti-1548	100	84	hcc	hcc	NOUN
dti-1548	100	85	=	=	X
dti-1548	100	86	hepatocellular	hepatocellular	ADJ
dti-1548	100	87	carcinoma	carcinoma	NOUN
dti-1548	100	88	.	.	PUNCT
dti-1548	101	1	table	table	NOUN
dti-1548	101	2	vii	vii	NOUN
dti-1548	101	3	distribution	distribution	NOUN
dti-1548	101	4	of	of	ADP
dti-1548	101	5	the	the	DET
dti-1548	101	6	studied	study	VERB
dti-1548	101	7	cases	case	NOUN
dti-1548	101	8	according	accord	VERB
dti-1548	101	9	to	to	ADP
dti-1548	101	10	ptnm	ptnm	PROPN
dti-1548	101	11	stage	stage	NOUN
dti-1548	101	12	(	(	PUNCT
dti-1548	101	13	ajcc	ajcc	PROPN
dti-1548	101	14	8th	8th	PROPN
dti-1548	101	15	edition	edition	NOUN
dti-1548	101	16	)	)	PUNCT
dti-1548	101	17	(	(	PUNCT
dti-1548	101	18	n	n	NOUN
dti-1548	101	19	=	=	SYM
dti-1548	101	20	32	32	NUM
dti-1548	101	21	)	)	PUNCT
dti-1548	101	22	stage	stage	NOUN
dti-1548	101	23	number	number	NOUN
dti-1548	101	24	%	%	NOUN
dti-1548	101	25	early	early	ADJ
dti-1548	101	26	stage	stage	NOUN
dti-1548	101	27	(	(	PUNCT
dti-1548	101	28	1	1	NUM
dti-1548	101	29	and	and	CCONJ
dti-1548	101	30	2	2	NUM
dti-1548	101	31	)	)	PUNCT
dti-1548	101	32	12	12	NUM
dti-1548	101	33	37.5	37.5	NUM
dti-1548	101	34	stage	stage	NOUN
dti-1548	101	35	i	i	NOUN
dti-1548	101	36	5	5	NUM
dti-1548	101	37	15.6	15.6	NUM
dti-1548	101	38	stage	stage	NOUN
dti-1548	101	39	ii	ii	NOUN
dti-1548	101	40	7	7	NUM
dti-1548	101	41	21.9	21.9	NUM
dti-1548	101	42	advanced	advanced	ADJ
dti-1548	101	43	stage	stage	NOUN
dti-1548	101	44	(	(	PUNCT
dti-1548	101	45	3	3	NUM
dti-1548	101	46	)	)	PUNCT
dti-1548	101	47	20	20	NUM
dti-1548	101	48	62.5	62.5	NUM
dti-1548	101	49	stage	stage	NOUN
dti-1548	101	50	iii	iii	NUM
dti-1548	101	51	20	20	NUM
dti-1548	101	52	62.5	62.5	NUM
dti-1548	101	53	stage	stage	NOUN
dti-1548	101	54	iv	iv	NUM
dti-1548	101	55	0	0	NUM
dti-1548	101	56	0.0	0.0	NUM
dti-1548	101	57	ajcc	ajcc	NOUN
dti-1548	101	58	=	=	SYM
dti-1548	101	59	american	american	ADJ
dti-1548	101	60	joint	joint	PROPN
dti-1548	101	61	committee	committee	PROPN
dti-1548	101	62	on	on	ADP
dti-1548	101	63	cancer	cancer	NOUN
dti-1548	101	64	;	;	PUNCT
dti-1548	102	1	tnm	tnm	PROPN
dti-1548	102	2	=	=	PUNCT
dti-1548	102	3	tumor	tumor	NOUN
dti-1548	102	4	-	-	PUNCT
dti-1548	102	5	node	node	NOUN
dti-1548	102	6	-	-	PUNCT
dti-1548	102	7	metastasis	metastasis	NOUN
dti-1548	102	8	.	.	PUNCT
dti-1548	103	1	table	table	NOUN
dti-1548	103	2	vi	vi	NOUN
dti-1548	103	3	distribution	distribution	NOUN
dti-1548	103	4	of	of	ADP
dti-1548	103	5	the	the	DET
dti-1548	103	6	studied	study	VERB
dti-1548	103	7	cases	case	NOUN
dti-1548	103	8	according	accord	VERB
dti-1548	103	9	to	to	ADP
dti-1548	103	10	edmondson	edmondson	PROPN
dti-1548	103	11	and	and	CCONJ
dti-1548	103	12	steiner	steiner	NOUN
dti-1548	103	13	grading	grade	VERB
dti-1548	103	14	system	system	NOUN
dti-1548	103	15	(	(	PUNCT
dti-1548	103	16	n	n	NOUN
dti-1548	103	17	=	=	SYM
dti-1548	103	18	32	32	NUM
dti-1548	103	19	)	)	PUNCT
dti-1548	103	20	grade	grade	NOUN
dti-1548	103	21	number	number	NOUN
dti-1548	103	22	%	%	NOUN
dti-1548	103	23	low	low	ADJ
dti-1548	103	24	grade	grade	NOUN
dti-1548	103	25	(	(	PUNCT
dti-1548	103	26	1	1	NUM
dti-1548	103	27	+	+	NUM
dti-1548	103	28	2	2	NUM
dti-1548	103	29	)	)	PUNCT
dti-1548	103	30	14	14	NUM
dti-1548	103	31	43.8	43.8	NUM
dti-1548	103	32	grade	grade	NOUN
dti-1548	103	33	i	i	NOUN
dti-1548	103	34	1	1	NUM
dti-1548	103	35	3.1	3.1	NUM
dti-1548	103	36	grade	grade	NOUN
dti-1548	103	37	ii	ii	PROPN
dti-1548	103	38	13	13	NUM
dti-1548	103	39	40.6	40.6	NUM
dti-1548	103	40	high	high	ADJ
dti-1548	103	41	grade	grade	NOUN
dti-1548	103	42	(	(	PUNCT
dti-1548	103	43	3	3	NUM
dti-1548	103	44	+	+	CCONJ
dti-1548	103	45	4	4	NUM
dti-1548	103	46	)	)	PUNCT
dti-1548	103	47	18	18	NUM
dti-1548	103	48	56.3	56.3	NUM
dti-1548	103	49	grade	grade	NOUN
dti-1548	103	50	iii	iii	NUM
dti-1548	103	51	3	3	NUM
dti-1548	103	52	9.4	9.4	NUM
dti-1548	103	53	grade	grade	NOUN
dti-1548	103	54	iv	iv	NUM
dti-1548	103	55	15	15	NUM
dti-1548	103	56	46.9	46.9	NUM
dti-1548	103	57	fig	fig	NOUN
dti-1548	103	58	.	.	PUNCT
dti-1548	104	1	1	1	NUM
dti-1548	104	2	bar	bar	NOUN
dti-1548	104	3	chart	chart	NOUN
dti-1548	104	4	representing	represent	VERB
dti-1548	104	5	the	the	DET
dti-1548	104	6	6	6	NUM
dti-1548	104	7	significantly	significantly	ADV
dti-1548	104	8	upregulated	upregulate	VERB
dti-1548	104	9	and	and	CCONJ
dti-1548	104	10	the	the	DET
dti-1548	104	11	13	13	NUM
dti-1548	104	12	significantly	significantly	ADV
dti-1548	104	13	downregulated	downregulate	VERB
dti-1548	104	14	genes	gene	NOUN
dti-1548	104	15	in	in	ADP
dti-1548	104	16	the	the	DET
dti-1548	104	17	hepatocellular	hepatocellular	ADJ
dti-1548	104	18	carcinoma	carcinoma	NOUN
dti-1548	104	19	group	group	NOUN
dti-1548	104	20	table	table	NOUN
dti-1548	104	21	viii	viii	VERB
dti-1548	104	22	the	the	DET
dti-1548	104	23	six	six	NUM
dti-1548	104	24	significantly	significantly	ADV
dti-1548	104	25	upregulated	upregulated	ADJ
dti-1548	104	26	genes	gene	NOUN
dti-1548	104	27	’	'	PUNCT
dti-1548	104	28	fold	fold	ADJ
dti-1548	104	29	regulation	regulation	NOUN
dti-1548	104	30	,	,	PUNCT
dti-1548	104	31	p	p	NOUN
dti-1548	104	32	values	value	NOUN
dti-1548	104	33	,	,	PUNCT
dti-1548	104	34	and	and	CCONJ
dti-1548	104	35	percentage	percentage	NOUN
dti-1548	104	36	of	of	ADP
dti-1548	104	37	cases	case	NOUN
dti-1548	104	38	showing	show	VERB
dti-1548	104	39	upregulation	upregulation	NOUN
dti-1548	104	40	of	of	ADP
dti-1548	104	41	these	these	DET
dti-1548	104	42	genes	gene	NOUN
dti-1548	104	43	position	position	NOUN
dti-1548	104	44	gene	gene	NOUN
dti-1548	104	45	symbol	symbol	NOUN
dti-1548	104	46	fold	fold	NOUN
dti-1548	104	47	regulation	regulation	NOUN
dti-1548	104	48	p	p	NOUN
dti-1548	104	49	number	number	NOUN
dti-1548	104	50	%	%	NOUN
dti-1548	104	51	a04	a04	PROPN
dti-1548	104	52	aebp1	aebp1	PROPN
dti-1548	105	1	6.694	6.694	NUM
dti-1548	105	2	0.045	0.045	NUM
dti-1548	105	3	*	*	SYM
dti-1548	105	4	29	29	NUM
dti-1548	105	5	90.6	90.6	NUM
dti-1548	105	6	a06	a06	NOUN
dti-1548	105	7	akt2	akt2	VERB
dti-1548	105	8	6.0287	6.0287	NUM
dti-1548	105	9	0.013	0.013	NUM
dti-1548	105	10	*	*	SYM
dti-1548	105	11	26	26	NUM
dti-1548	105	12	81.3	81.3	NUM
dti-1548	105	13	c01	c01	NOUN
dti-1548	105	14	fos	fos	VERB
dti-1548	105	15	3.9608	3.9608	NUM
dti-1548	105	16	0.045	0.045	NUM
dti-1548	105	17	*	*	SYM
dti-1548	105	18	25	25	NUM
dti-1548	105	19	78.1	78.1	NUM
dti-1548	105	20	e11	e11	NOUN
dti-1548	105	21	pik3r1	pik3r1	NOUN
dti-1548	105	22	4.1363	4.1363	NUM
dti-1548	105	23	0.020	0.020	NUM
dti-1548	105	24	*	*	SYM
dti-1548	105	25	25	25	NUM
dti-1548	105	26	78.1	78.1	NUM
dti-1548	105	27	f05	f05	NOUN
dti-1548	105	28	prkci	prkci	VERB
dti-1548	105	29	7.7467	7.7467	NUM
dti-1548	105	30	0.006	0.006	NUM
dti-1548	105	31	*	*	SYM
dti-1548	105	32	28	28	NUM
dti-1548	105	33	87.5	87.5	NUM
dti-1548	105	34	g04	g04	NOUN
dti-1548	105	35	shc1	shc1	PROPN
dti-1548	105	36	11.8326	11.8326	NUM
dti-1548	105	37	0.001	0.001	NUM
dti-1548	105	38	*	*	SYM
dti-1548	105	39	30	30	NUM
dti-1548	105	40	93.8	93.8	NUM
dti-1548	105	41	p	p	NOUN
dti-1548	106	1	=	=	PUNCT
dti-1548	107	1	p	p	NOUN
dti-1548	107	2	values	value	NOUN
dti-1548	107	3	for	for	ADP
dti-1548	107	4	mann	mann	PROPN
dti-1548	107	5	-	-	PUNCT
dti-1548	107	6	whitney	whitney	PROPN
dti-1548	107	7	test	test	NOUN
dti-1548	107	8	for	for	ADP
dti-1548	107	9	comparing	compare	VERB
dti-1548	107	10	between	between	ADP
dti-1548	107	11	the	the	DET
dti-1548	107	12	two	two	NUM
dti-1548	107	13	groups	group	NOUN
dti-1548	107	14	.	.	PUNCT
dti-1548	108	1	*	*	PUNCT
dti-1548	108	2	statistically	statistically	ADV
dti-1548	108	3	significant	significant	ADJ
dti-1548	108	4	at	at	ADP
dti-1548	108	5	p	p	NOUN
dti-1548	108	6	≤	≤	NUM
dti-1548	108	7	0.05	0.05	NUM
dti-1548	108	8	.	.	PUNCT
dti-1548	109	1	mabrouk	mabrouk	PROPN
dti-1548	110	1	et	et	NOUN
dti-1548	110	2	al	al	PROPN
dti-1548	110	3	5	5	NUM
dti-1548	110	4	©	©	PROPN
dti-1548	110	5	2020	2020	NUM
dti-1548	110	6	the	the	DET
dti-1548	110	7	authors	author	NOUN
dti-1548	110	8	.	.	PUNCT
dti-1548	111	1	published	publish	VERB
dti-1548	111	2	by	by	ADP
dti-1548	111	3	aboutscience	aboutscience	NOUN
dti-1548	111	4	table	table	NOUN
dti-1548	111	5	ix	ix	ADP
dti-1548	111	6	the	the	DET
dti-1548	111	7	13	13	NUM
dti-1548	111	8	significantly	significantly	ADV
dti-1548	111	9	downregulated	downregulate	VERB
dti-1548	111	10	genes	gene	NOUN
dti-1548	111	11	’	'	PUNCT
dti-1548	111	12	fold	fold	ADJ
dti-1548	111	13	regulation	regulation	NOUN
dti-1548	111	14	,	,	PUNCT
dti-1548	111	15	p	p	NOUN
dti-1548	111	16	values	value	NOUN
dti-1548	111	17	,	,	PUNCT
dti-1548	111	18	and	and	CCONJ
dti-1548	111	19	percentage	percentage	NOUN
dti-1548	111	20	of	of	ADP
dti-1548	111	21	cases	case	NOUN
dti-1548	111	22	showing	show	VERB
dti-1548	111	23	downregulation	downregulation	NOUN
dti-1548	111	24	of	of	ADP
dti-1548	111	25	these	these	DET
dti-1548	111	26	genes	gene	NOUN
dti-1548	111	27	position	position	NOUN
dti-1548	111	28	gene	gene	NOUN
dti-1548	111	29	symbol	symbol	NOUN
dti-1548	111	30	fold	fold	NOUN
dti-1548	111	31	regulation	regulation	NOUN
dti-1548	111	32	p	p	NOUN
dti-1548	111	33	number	number	NOUN
dti-1548	111	34	%	%	NOUN
dti-1548	111	35	a03	a03	VERB
dti-1548	111	36	adrb3	adrb3	NOUN
dti-1548	111	37	−11.3685	−11.3685	PROPN
dti-1548	111	38	0.010	0.010	NUM
dti-1548	111	39	*	*	SYM
dti-1548	111	40	23	23	NUM
dti-1548	111	41	71.9	71.9	NUM
dti-1548	111	42	b02	b02	NOUN
dti-1548	111	43	cebpa	cebpa	NOUN
dti-1548	111	44	−5.3981	−5.3981	PROPN
dti-1548	111	45	0.041	0.041	NUM
dti-1548	111	46	*	*	SYM
dti-1548	111	47	22	22	NUM
dti-1548	111	48	68.8	68.8	NUM
dti-1548	111	49	b07	b07	NOUN
dti-1548	111	50	dusp14	dusp14	VERB
dti-1548	111	51	−6.5717	−6.5717	NOUN
dti-1548	111	52	0.016	0.016	NUM
dti-1548	111	53	*	*	SYM
dti-1548	111	54	23	23	NUM
dti-1548	111	55	71.9	71.9	NUM
dti-1548	111	56	b10	b10	PROPN
dti-1548	111	57	ercc1	ercc1	PROPN
dti-1548	111	58	−8.7853	−8.7853	PROPN
dti-1548	111	59	0.037	0.037	NUM
dti-1548	111	60	*	*	SYM
dti-1548	111	61	22	22	NUM
dti-1548	111	62	68.8	68.8	NUM
dti-1548	111	63	c03	c03	NOUN
dti-1548	111	64	frs3	frs3	PROPN
dti-1548	111	65	−35.5177	−35.5177	PROPN
dti-1548	112	1	0.006	0.006	NUM
dti-1548	112	2	*	*	SYM
dti-1548	112	3	27	27	NUM
dti-1548	112	4	84.4	84.4	NUM
dti-1548	112	5	d02	d02	NOUN
dti-1548	112	6	igf2	igf2	PROPN
dti-1548	112	7	−8.6788	−8.6788	PROPN
dti-1548	112	8	0.013	0.013	NUM
dti-1548	112	9	*	*	SYM
dti-1548	112	10	25	25	NUM
dti-1548	112	11	78.1	78.1	NUM
dti-1548	112	12	d04	d04	NOUN
dti-1548	112	13	ins	in	NOUN
dti-1548	112	14	−31.7678	−31.7678	X
dti-1548	112	15	0.002	0.002	NUM
dti-1548	112	16	*	*	SYM
dti-1548	112	17	30	30	NUM
dti-1548	112	18	93.8	93.8	NUM
dti-1548	112	19	d07	d07	NOUN
dti-1548	112	20	irs1	irs1	NOUN
dti-1548	112	21	−8.0248	−8.0248	X
dti-1548	112	22	0.037	0.037	NUM
dti-1548	112	23	*	*	SYM
dti-1548	112	24	22	22	NUM
dti-1548	112	25	68.8	68.8	NUM
dti-1548	112	26	d10	d10	PROPN
dti-1548	112	27	jun	jun	PROPN
dti-1548	112	28	−13.0027	−13.0027	PROPN
dti-1548	112	29	0.020	0.020	NUM
dti-1548	112	30	*	*	SYM
dti-1548	112	31	23	23	NUM
dti-1548	112	32	71.9	71.9	NUM
dti-1548	112	33	e04	e04	NOUN
dti-1548	112	34	mtor	mtor	NOUN
dti-1548	112	35	−9.0478	−9.0478	PROPN
dti-1548	112	36	0.045	0.045	NUM
dti-1548	112	37	*	*	SYM
dti-1548	112	38	26	26	NUM
dti-1548	112	39	81.3	81.3	NUM
dti-1548	112	40	e12	e12	NOUN
dti-1548	112	41	pik3r2	pik3r2	ADV
dti-1548	112	42	−2.8856	−2.8856	NOUN
dti-1548	112	43	0.037	0.037	NUM
dti-1548	112	44	*	*	NOUN
dti-1548	112	45	23	23	NUM
dti-1548	112	46	71.9	71.9	NUM
dti-1548	112	47	f03	f03	NOUN
dti-1548	112	48	ppp1ca	ppp1ca	NOUN
dti-1548	112	49	−46.4755	−46.4755	PROPN
dti-1548	112	50	0.002	0.002	NUM
dti-1548	112	51	*	*	SYM
dti-1548	112	52	29	29	NUM
dti-1548	112	53	90.6	90.6	NUM
dti-1548	112	54	f12	f12	NOUN
dti-1548	112	55	rps6ka1	rps6ka1	PROPN
dti-1548	112	56	−5.653	−5.653	PROPN
dti-1548	112	57	0.025	0.025	NUM
dti-1548	112	58	*	*	SYM
dti-1548	112	59	24	24	NUM
dti-1548	112	60	75.0	75.0	NUM
dti-1548	112	61	p	p	NOUN
dti-1548	112	62	=	=	PUNCT
dti-1548	112	63	p	p	NOUN
dti-1548	112	64	values	value	NOUN
dti-1548	112	65	for	for	ADP
dti-1548	112	66	mann	mann	PROPN
dti-1548	112	67	-	-	PUNCT
dti-1548	112	68	whitney	whitney	PROPN
dti-1548	112	69	test	test	NOUN
dti-1548	112	70	for	for	ADP
dti-1548	112	71	comparing	compare	VERB
dti-1548	112	72	between	between	ADP
dti-1548	112	73	the	the	DET
dti-1548	112	74	two	two	NUM
dti-1548	112	75	groups	group	NOUN
dti-1548	112	76	.	.	PUNCT
dti-1548	113	1	*	*	PUNCT
dti-1548	113	2	statistically	statistically	ADV
dti-1548	113	3	significant	significant	ADJ
dti-1548	113	4	at	at	ADP
dti-1548	113	5	p	p	NOUN
dti-1548	113	6	≤	≤	NUM
dti-1548	113	7	0.05	0.05	NUM
dti-1548	114	1	.	.	PUNCT
dti-1548	114	2	fig	fig	NOUN
dti-1548	114	3	.	.	PUNCT
dti-1548	115	1	2	2	NUM
dti-1548	115	2	scatter	scatter	NOUN
dti-1548	115	3	plot	plot	NOUN
dti-1548	115	4	representing	represent	VERB
dti-1548	115	5	the	the	DET
dti-1548	115	6	normalized	normalize	VERB
dti-1548	115	7	expression	expression	NOUN
dti-1548	115	8	of	of	ADP
dti-1548	115	9	each	each	DET
dti-1548	115	10	gene	gene	NOUN
dti-1548	115	11	on	on	ADP
dti-1548	115	12	the	the	DET
dti-1548	115	13	polymerase	polymerase	NOUN
dti-1548	115	14	chain	chain	NOUN
dti-1548	115	15	reaction	reaction	NOUN
dti-1548	115	16	array	array	NOUN
dti-1548	115	17	between	between	ADP
dti-1548	115	18	the	the	DET
dti-1548	115	19	two	two	NUM
dti-1548	115	20	groups	group	NOUN
dti-1548	115	21	.	.	PUNCT
dti-1548	116	1	log	log	VERB
dti-1548	116	2	base	base	NOUN
dti-1548	116	3	10	10	NUM
dti-1548	116	4	of	of	ADP
dti-1548	116	5	2	2	NUM
dti-1548	116	6	–	–	PUNCT
dti-1548	116	7	δct	δct	NOUN
dti-1548	116	8	value	value	NOUN
dti-1548	116	9	of	of	ADP
dti-1548	116	10	each	each	DET
dti-1548	116	11	gene	gene	NOUN
dti-1548	116	12	in	in	ADP
dti-1548	116	13	the	the	DET
dti-1548	116	14	control	control	NOUN
dti-1548	116	15	group	group	NOUN
dti-1548	116	16	is	be	AUX
dti-1548	116	17	plotted	plot	VERB
dti-1548	116	18	on	on	ADP
dti-1548	116	19	the	the	DET
dti-1548	116	20	x	x	NOUN
dti-1548	116	21	-	-	NOUN
dti-1548	116	22	axis	axis	NOUN
dti-1548	116	23	against	against	ADP
dti-1548	116	24	the	the	DET
dti-1548	116	25	corresponding	corresponding	ADJ
dti-1548	116	26	value	value	NOUN
dti-1548	116	27	in	in	ADP
dti-1548	116	28	the	the	DET
dti-1548	116	29	hepatocellular	hepatocellular	ADJ
dti-1548	116	30	carcinoma	carcinoma	NOUN
dti-1548	116	31	(	(	PUNCT
dti-1548	116	32	hcc	hcc	NOUN
dti-1548	116	33	)	)	PUNCT
dti-1548	116	34	group	group	NOUN
dti-1548	116	35	,	,	PUNCT
dti-1548	116	36	which	which	PRON
dti-1548	116	37	is	be	AUX
dti-1548	116	38	plotted	plot	VERB
dti-1548	116	39	on	on	ADP
dti-1548	116	40	the	the	DET
dti-1548	116	41	y	y	NOUN
dti-1548	116	42	-	-	PUNCT
dti-1548	116	43	axis	axis	NOUN
dti-1548	116	44	to	to	PART
dti-1548	116	45	visualize	visualize	VERB
dti-1548	116	46	gene	gene	NOUN
dti-1548	116	47	expression	expression	NOUN
dti-1548	116	48	changes	change	NOUN
dti-1548	116	49	.	.	PUNCT
dti-1548	117	1	the	the	DET
dti-1548	117	2	central	central	ADJ
dti-1548	117	3	boundary	boundary	ADJ
dti-1548	117	4	line	line	NOUN
dti-1548	117	5	indicates	indicate	VERB
dti-1548	117	6	unchanged	unchanged	ADJ
dti-1548	117	7	gene	gene	NOUN
dti-1548	117	8	expression	expression	NOUN
dti-1548	117	9	.	.	PUNCT
dti-1548	118	1	the	the	DET
dti-1548	118	2	upper	upper	ADJ
dti-1548	118	3	left	left	ADJ
dti-1548	118	4	section	section	NOUN
dti-1548	118	5	of	of	ADP
dti-1548	118	6	the	the	DET
dti-1548	118	7	scatter	scatter	NOUN
dti-1548	118	8	plot	plot	NOUN
dti-1548	118	9	(	(	PUNCT
dti-1548	118	10	above	above	ADP
dti-1548	118	11	the	the	DET
dti-1548	118	12	fold	fold	ADJ
dti-1548	118	13	-	-	PUNCT
dti-1548	118	14	change	change	NOUN
dti-1548	118	15	boundary	boundary	ADJ
dti-1548	118	16	lines	line	NOUN
dti-1548	118	17	)	)	PUNCT
dti-1548	118	18	contains	contain	VERB
dti-1548	118	19	genes	gene	NOUN
dti-1548	118	20	upregulated	upregulate	VERB
dti-1548	118	21	in	in	ADP
dti-1548	118	22	the	the	DET
dti-1548	118	23	hcc	hcc	PROPN
dti-1548	118	24	group	group	NOUN
dti-1548	118	25	as	as	SCONJ
dti-1548	118	26	compared	compare	VERB
dti-1548	118	27	to	to	ADP
dti-1548	118	28	the	the	DET
dti-1548	118	29	control	control	NOUN
dti-1548	118	30	group	group	NOUN
dti-1548	118	31	.	.	PUNCT
dti-1548	119	1	the	the	DET
dti-1548	119	2	lower	low	ADJ
dti-1548	119	3	right	right	ADJ
dti-1548	119	4	section	section	NOUN
dti-1548	119	5	of	of	ADP
dti-1548	119	6	the	the	DET
dti-1548	119	7	scatter	scatter	NOUN
dti-1548	119	8	plot	plot	NOUN
dti-1548	119	9	(	(	PUNCT
dti-1548	119	10	below	below	ADP
dti-1548	119	11	the	the	DET
dti-1548	119	12	fold	fold	ADJ
dti-1548	119	13	-	-	PUNCT
dti-1548	119	14	change	change	NOUN
dti-1548	119	15	boundary	boundary	ADJ
dti-1548	119	16	lines	line	NOUN
dti-1548	119	17	)	)	PUNCT
dti-1548	119	18	contains	contain	VERB
dti-1548	119	19	genes	gene	NOUN
dti-1548	119	20	downregulated	downregulate	VERB
dti-1548	119	21	in	in	ADP
dti-1548	119	22	the	the	DET
dti-1548	119	23	hcc	hcc	PROPN
dti-1548	119	24	group	group	NOUN
dti-1548	119	25	as	as	ADP
dti-1548	119	26	compared	compare	VERB
dti-1548	119	27	to	to	ADP
dti-1548	119	28	the	the	DET
dti-1548	119	29	control	control	NOUN
dti-1548	119	30	group	group	NOUN
dti-1548	119	31	.	.	PUNCT
dti-1548	120	1	it	it	PRON
dti-1548	120	2	shows	show	VERB
dti-1548	120	3	the	the	DET
dti-1548	120	4	upregulated	upregulated	ADJ
dti-1548	120	5	genes	gene	NOUN
dti-1548	120	6	in	in	ADP
dti-1548	120	7	red	red	ADJ
dti-1548	120	8	and	and	CCONJ
dti-1548	120	9	the	the	DET
dti-1548	120	10	downregulated	downregulate	VERB
dti-1548	120	11	genes	gene	NOUN
dti-1548	120	12	in	in	ADP
dti-1548	120	13	green	green	ADJ
dti-1548	120	14	.	.	PUNCT
dti-1548	121	1	fig	fig	NOUN
dti-1548	121	2	.	.	PUNCT
dti-1548	122	1	3	3	NUM
dti-1548	122	2	heat	heat	NOUN
dti-1548	122	3	map	map	NOUN
dti-1548	122	4	is	be	AUX
dti-1548	122	5	a	a	DET
dti-1548	122	6	color	color	NOUN
dti-1548	122	7	-	-	PUNCT
dti-1548	122	8	coded	code	VERB
dti-1548	122	9	representation	representation	NOUN
dti-1548	122	10	of	of	ADP
dti-1548	122	11	fold	fold	ADJ
dti-1548	122	12	regulation	regulation	NOUN
dti-1548	122	13	expression	expression	NOUN
dti-1548	122	14	data	datum	NOUN
dti-1548	122	15	between	between	ADP
dti-1548	122	16	hcc	hcc	PROPN
dti-1548	122	17	and	and	CCONJ
dti-1548	122	18	control	control	NOUN
dti-1548	122	19	groups	group	NOUN
dti-1548	122	20	overlaid	overlay	VERB
dti-1548	122	21	onto	onto	ADP
dti-1548	122	22	the	the	DET
dti-1548	122	23	polymerase	polymerase	NOUN
dti-1548	122	24	chain	chain	NOUN
dti-1548	122	25	reaction	reaction	NOUN
dti-1548	122	26	array	array	VERB
dti-1548	122	27	plate	plate	NOUN
dti-1548	122	28	layout	layout	NOUN
dti-1548	122	29	.	.	PUNCT
dti-1548	123	1	the	the	DET
dti-1548	123	2	black	black	ADJ
dti-1548	123	3	color	color	NOUN
dti-1548	123	4	represents	represent	VERB
dti-1548	123	5	the	the	DET
dti-1548	123	6	average	average	ADJ
dti-1548	123	7	magnitude	magnitude	NOUN
dti-1548	123	8	of	of	ADP
dti-1548	123	9	gene	gene	NOUN
dti-1548	123	10	expression	expression	NOUN
dti-1548	123	11	.	.	PUNCT
dti-1548	124	1	the	the	DET
dti-1548	124	2	brightest	bright	ADJ
dti-1548	124	3	green	green	NOUN
dti-1548	124	4	represents	represent	VERB
dti-1548	124	5	the	the	DET
dti-1548	124	6	most	most	ADV
dti-1548	124	7	downregulated	downregulate	VERB
dti-1548	124	8	genes	gene	NOUN
dti-1548	124	9	,	,	PUNCT
dti-1548	124	10	the	the	DET
dti-1548	124	11	brightest	bright	ADJ
dti-1548	124	12	red	red	NOUN
dti-1548	124	13	represents	represent	VERB
dti-1548	124	14	the	the	DET
dti-1548	124	15	most	most	ADV
dti-1548	124	16	upregulated	upregulated	ADJ
dti-1548	124	17	genes	gene	NOUN
dti-1548	124	18	in	in	ADP
dti-1548	124	19	the	the	DET
dti-1548	124	20	hcc	hcc	PROPN
dti-1548	124	21	cases	case	NOUN
dti-1548	124	22	compared	compare	VERB
dti-1548	124	23	to	to	ADP
dti-1548	124	24	the	the	DET
dti-1548	124	25	normal	normal	ADJ
dti-1548	124	26	controls	control	NOUN
dti-1548	124	27	.	.	PUNCT
dti-1548	125	1	vegfa	vegfa	PROPN
dti-1548	125	2	was	be	AUX
dti-1548	125	3	downregulated	downregulate	VERB
dti-1548	125	4	(	(	PUNCT
dti-1548	125	5	fold	fold	ADJ
dti-1548	125	6	regulation	regulation	NOUN
dti-1548	125	7	of	of	ADP
dti-1548	125	8	−3.2345	−3.2345	NUM
dti-1548	125	9	)	)	PUNCT
dti-1548	125	10	in	in	ADP
dti-1548	125	11	71.9	71.9	NUM
dti-1548	125	12	%	%	NOUN
dti-1548	125	13	(	(	PUNCT
dti-1548	125	14	23/32	23/32	NUM
dti-1548	125	15	)	)	PUNCT
dti-1548	125	16	of	of	ADP
dti-1548	125	17	cases	case	NOUN
dti-1548	125	18	in	in	ADP
dti-1548	125	19	the	the	DET
dti-1548	125	20	present	present	ADJ
dti-1548	125	21	study	study	NOUN
dti-1548	125	22	,	,	PUNCT
dti-1548	125	23	although	although	SCONJ
dti-1548	125	24	this	this	PRON
dti-1548	125	25	did	do	AUX
dti-1548	125	26	not	not	PART
dti-1548	125	27	reach	reach	VERB
dti-1548	125	28	statistical	statistical	ADJ
dti-1548	125	29	significance	significance	NOUN
dti-1548	125	30	.	.	PUNCT
dti-1548	126	1	a	a	DET
dti-1548	126	2	scatter	scatter	NOUN
dti-1548	126	3	plot	plot	NOUN
dti-1548	126	4	and	and	CCONJ
dti-1548	126	5	a	a	DET
dti-1548	126	6	heat	heat	NOUN
dti-1548	126	7	map	map	NOUN
dti-1548	126	8	were	be	AUX
dti-1548	126	9	generated	generate	VERB
dti-1548	126	10	on	on	ADP
dti-1548	126	11	the	the	DET
dti-1548	126	12	online	online	ADJ
dti-1548	126	13	data	data	PROPN
dti-1548	126	14	analysis	analysis	NOUN
dti-1548	126	15	web	web	NOUN
dti-1548	126	16	portal	portal	NOUN
dti-1548	126	17	representing	represent	VERB
dti-1548	126	18	the	the	DET
dti-1548	126	19	distribution	distribution	NOUN
dti-1548	126	20	of	of	ADP
dti-1548	126	21	average	average	ADJ
dti-1548	126	22	gene	gene	NOUN
dti-1548	126	23	expression	expression	NOUN
dti-1548	126	24	levels	level	NOUN
dti-1548	126	25	(	(	PUNCT
dti-1548	126	26	figs	fig	NOUN
dti-1548	126	27	.	.	X
dti-1548	127	1	1	1	NUM
dti-1548	127	2	and	and	CCONJ
dti-1548	127	3	2	2	NUM
dti-1548	127	4	respectively	respectively	ADV
dti-1548	127	5	)	)	PUNCT
dti-1548	127	6	.	.	PUNCT
dti-1548	128	1	nonsupervised	nonsupervise	VERB
dti-1548	128	2	hierarchical	hierarchical	ADJ
dti-1548	128	3	clustering	clustering	NOUN
dti-1548	128	4	of	of	ADP
dti-1548	128	5	all	all	DET
dti-1548	128	6	cases	case	NOUN
dti-1548	128	7	and	and	CCONJ
dti-1548	128	8	controls	control	NOUN
dti-1548	128	9	according	accord	VERB
dti-1548	128	10	to	to	ADP
dti-1548	128	11	their	their	PRON
dti-1548	128	12	gene	gene	NOUN
dti-1548	128	13	expression	expression	NOUN
dti-1548	128	14	profile	profile	NOUN
dti-1548	128	15	by	by	ADP
dti-1548	128	16	the	the	DET
dti-1548	128	17	data	datum	NOUN
dti-1548	128	18	analysis	analysis	NOUN
dti-1548	128	19	web	web	NOUN
dti-1548	128	20	portal	portal	NOUN
dti-1548	128	21	the	the	DET
dti-1548	128	22	included	include	VERB
dti-1548	128	23	cases	case	NOUN
dti-1548	128	24	were	be	AUX
dti-1548	128	25	a	a	DET
dti-1548	128	26	homogeneous	homogeneous	ADJ
dti-1548	128	27	population	population	NOUN
dti-1548	128	28	with	with	ADP
dti-1548	128	29	no	no	DET
dti-1548	128	30	outstanding	outstanding	ADJ
dti-1548	128	31	clustering	clustering	NOUN
dti-1548	128	32	as	as	SCONJ
dti-1548	128	33	evidenced	evidence	VERB
dti-1548	128	34	by	by	ADP
dti-1548	128	35	the	the	DET
dti-1548	128	36	dendrograms	dendrogram	NOUN
dti-1548	128	37	.	.	PUNCT
dti-1548	129	1	this	this	PRON
dti-1548	129	2	further	far	ADV
dti-1548	129	3	supports	support	VERB
dti-1548	129	4	the	the	DET
dti-1548	129	5	study	study	NOUN
dti-1548	129	6	design	design	NOUN
dti-1548	129	7	as	as	SCONJ
dti-1548	129	8	it	it	PRON
dti-1548	129	9	included	include	VERB
dti-1548	129	10	a	a	DET
dti-1548	129	11	specific	specific	ADJ
dti-1548	129	12	cohort	cohort	NOUN
dti-1548	129	13	of	of	ADP
dti-1548	129	14	hccs	hccs	NOUN
dti-1548	129	15	:	:	PUNCT
dti-1548	129	16	egyptian	egyptian	ADJ
dti-1548	129	17	ethnicity	ethnicity	NOUN
dti-1548	129	18	and	and	CCONJ
dti-1548	129	19	hcv	hcv	PROPN
dti-1548	129	20	genotype	genotype	NOUN
dti-1548	129	21	4	4	NUM
dti-1548	129	22	etiology	etiology	NOUN
dti-1548	129	23	.	.	PUNCT
dti-1548	130	1	correlations	correlation	NOUN
dti-1548	130	2	between	between	ADP
dti-1548	130	3	the	the	DET
dti-1548	130	4	gene	gene	NOUN
dti-1548	130	5	expression	expression	NOUN
dti-1548	130	6	levels	level	NOUN
dti-1548	130	7	and	and	CCONJ
dti-1548	130	8	demographic	demographic	ADJ
dti-1548	130	9	data	datum	NOUN
dti-1548	130	10	in	in	ADP
dti-1548	130	11	hcc	hcc	PROPN
dti-1548	130	12	patients	patient	NOUN
dti-1548	130	13	age	age	NOUN
dti-1548	130	14	:	:	PUNCT
dti-1548	130	15	there	there	PRON
dti-1548	130	16	were	be	VERB
dti-1548	130	17	significant	significant	ADJ
dti-1548	130	18	differences	difference	NOUN
dti-1548	130	19	in	in	ADP
dti-1548	130	20	three	three	NUM
dti-1548	130	21	gene	gene	NOUN
dti-1548	130	22	expression	expression	NOUN
dti-1548	130	23	levels	level	NOUN
dti-1548	130	24	as	as	SCONJ
dti-1548	130	25	regards	regard	VERB
dti-1548	130	26	age	age	NOUN
dti-1548	130	27	;	;	PUNCT
dti-1548	130	28	aebp1	aebp1	PROPN
dti-1548	130	29	,	,	PUNCT
dti-1548	130	30	akt1	akt1	PROPN
dti-1548	130	31	,	,	PUNCT
dti-1548	130	32	and	and	CCONJ
dti-1548	130	33	fbp1	fbp1	NOUN
dti-1548	130	34	genes	gene	NOUN
dti-1548	130	35	were	be	AUX
dti-1548	130	36	significantly	significantly	ADV
dti-1548	130	37	overexpressed	overexpresse	VERB
dti-1548	130	38	in	in	ADP
dti-1548	130	39	hcc	hcc	PROPN
dti-1548	130	40	patients	patient	NOUN
dti-1548	130	41	≤60	≤60	PROPN
dti-1548	130	42	years	year	NOUN
dti-1548	130	43	of	of	ADP
dti-1548	130	44	age	age	NOUN
dti-1548	130	45	compared	compare	VERB
dti-1548	130	46	to	to	ADP
dti-1548	130	47	hcc	hcc	PROPN
dti-1548	130	48	patients	patient	NOUN
dti-1548	130	49	>	>	PUNCT
dti-1548	130	50	60	60	NUM
dti-1548	130	51	years	year	NOUN
dti-1548	130	52	of	of	ADP
dti-1548	130	53	age	age	NOUN
dti-1548	130	54	(	(	PUNCT
dti-1548	130	55	tab	tab	NOUN
dti-1548	130	56	.	.	PUNCT
dti-1548	130	57	x	x	X
dti-1548	130	58	)	)	PUNCT
dti-1548	130	59	.	.	PUNCT
dti-1548	131	1	gender	gender	NOUN
dti-1548	131	2	:	:	PUNCT
dti-1548	131	3	dok1	dok1	PROPN
dti-1548	131	4	was	be	AUX
dti-1548	131	5	significantly	significantly	ADV
dti-1548	131	6	overexpressed	overexpresse	VERB
dti-1548	131	7	in	in	ADP
dti-1548	131	8	female	female	ADJ
dti-1548	131	9	patients	patient	NOUN
dti-1548	131	10	(	(	PUNCT
dti-1548	131	11	p	p	X
dti-1548	131	12	=	=	NOUN
dti-1548	131	13	0.037	0.037	NUM
dti-1548	131	14	)	)	PUNCT
dti-1548	131	15	.	.	PUNCT
dti-1548	132	1	stage	stage	NOUN
dti-1548	132	2	:	:	PUNCT
dti-1548	132	3	there	there	PRON
dti-1548	132	4	were	be	VERB
dti-1548	132	5	no	no	DET
dti-1548	132	6	statistically	statistically	ADV
dti-1548	132	7	significant	significant	ADJ
dti-1548	132	8	differences	difference	NOUN
dti-1548	132	9	detected	detect	VERB
dti-1548	132	10	in	in	ADP
dti-1548	132	11	the	the	DET
dti-1548	132	12	gene	gene	NOUN
dti-1548	132	13	expression	expression	NOUN
dti-1548	132	14	levels	level	NOUN
dti-1548	132	15	between	between	ADP
dti-1548	132	16	early	early	ADJ
dti-1548	132	17	ptnm	ptnm	NOUN
dti-1548	132	18	stage	stage	NOUN
dti-1548	132	19	(	(	PUNCT
dti-1548	132	20	pt1,2	pt1,2	NOUN
dti-1548	132	21	)	)	PUNCT
dti-1548	132	22	and	and	CCONJ
dti-1548	132	23	late	late	ADJ
dti-1548	132	24	stage	stage	NOUN
dti-1548	132	25	(	(	PUNCT
dti-1548	132	26	pt3,4	pt3,4	ADJ
dti-1548	132	27	)	)	PUNCT
dti-1548	133	1	hcc	hcc	PROPN
dti-1548	133	2	tumors	tumor	NOUN
dti-1548	133	3	.	.	PUNCT
dti-1548	134	1	grade	grade	NOUN
dti-1548	134	2	:	:	PUNCT
dti-1548	134	3	gsk3a	gsk3a	PROPN
dti-1548	134	4	was	be	AUX
dti-1548	134	5	significantly	significantly	ADV
dti-1548	134	6	overexpressed	overexpresse	VERB
dti-1548	134	7	in	in	ADP
dti-1548	134	8	lowgrade	lowgrade	NOUN
dti-1548	134	9	tumors	tumor	NOUN
dti-1548	134	10	as	as	SCONJ
dti-1548	134	11	compared	compare	VERB
dti-1548	134	12	to	to	ADP
dti-1548	134	13	high	high	ADJ
dti-1548	134	14	-	-	PUNCT
dti-1548	134	15	grade	grade	NOUN
dti-1548	134	16	ones	one	NOUN
dti-1548	134	17	where	where	SCONJ
dti-1548	134	18	it	it	PRON
dti-1548	134	19	was	be	AUX
dti-1548	134	20	normally	normally	ADV
dti-1548	134	21	expressed	express	VERB
dti-1548	134	22	(	(	PUNCT
dti-1548	134	23	p	p	NOUN
dti-1548	134	24	=	=	NOUN
dti-1548	134	25	0.002	0.002	NUM
dti-1548	134	26	)	)	PUNCT
dti-1548	134	27	possible	possible	ADJ
dti-1548	134	28	therapeutic	therapeutic	ADJ
dti-1548	134	29	targets	target	NOUN
dti-1548	134	30	in	in	ADP
dti-1548	134	31	igf1r	igf1r	ADJ
dti-1548	134	32	pathway	pathway	NOUN
dti-1548	134	33	in	in	ADP
dti-1548	134	34	egyptian	egyptian	PROPN
dti-1548	134	35	hcv	hcv	PROPN
dti-1548	134	36	related	relate	VERB
dti-1548	134	37	hcc6	hcc6	PROPN
dti-1548	135	1	©	©	PROPN
dti-1548	135	2	2020	2020	NUM
dti-1548	135	3	the	the	DET
dti-1548	135	4	authors	author	NOUN
dti-1548	135	5	.	.	PUNCT
dti-1548	136	1	published	publish	VERB
dti-1548	136	2	by	by	ADP
dti-1548	136	3	aboutscience	aboutscience	NOUN
dti-1548	136	4	table	table	NOUN
dti-1548	136	5	x	x	PUNCT
dti-1548	136	6	differentially	differentially	ADV
dti-1548	136	7	expressed	express	VERB
dti-1548	136	8	genes	gene	NOUN
dti-1548	136	9	between	between	ADP
dti-1548	136	10	hcc	hcc	PROPN
dti-1548	136	11	cases	case	NOUN
dti-1548	136	12	whose	whose	DET
dti-1548	136	13	age	age	NOUN
dti-1548	136	14	is	be	AUX
dti-1548	136	15	≤60	≤60	ADJ
dti-1548	136	16	years	year	NOUN
dti-1548	136	17	and	and	CCONJ
dti-1548	136	18	those	those	PRON
dti-1548	136	19	who	who	PRON
dti-1548	136	20	are	be	AUX
dti-1548	136	21	>	>	X
dti-1548	136	22	60	60	NUM
dti-1548	136	23	years	year	NOUN
dti-1548	136	24	of	of	ADP
dti-1548	136	25	age	age	NOUN
dti-1548	136	26	as	as	SCONJ
dti-1548	136	27	regards	regard	VERB
dti-1548	136	28	human	human	ADJ
dti-1548	136	29	insulin	insulin	NOUN
dti-1548	136	30	signaling	signal	VERB
dti-1548	136	31	pathway	pathway	NOUN
dti-1548	136	32	gene	gene	NOUN
dti-1548	136	33	expression	expression	NOUN
dti-1548	136	34	levels	level	NOUN
dti-1548	136	35	gene	gene	NOUN
dti-1548	136	36	symbol	symbol	NOUN
dti-1548	136	37	group	group	NOUN
dti-1548	136	38	1	1	NUM
dti-1548	136	39	age	age	NOUN
dti-1548	136	40	≤60	≤60	PROPN
dti-1548	136	41	years	year	NOUN
dti-1548	136	42	group	group	NOUN
dti-1548	136	43	1	1	NUM
dti-1548	136	44	age	age	NOUN
dti-1548	136	45	>	>	NOUN
dti-1548	136	46	60	60	NUM
dti-1548	136	47	years	year	NOUN
dti-1548	136	48	p	p	NOUN
dti-1548	136	49	fold	fold	ADJ
dti-1548	136	50	regulation	regulation	NOUN
dti-1548	136	51	fold	fold	NOUN
dti-1548	136	52	regulation	regulation	NOUN
dti-1548	136	53	aebp1	aebp1	PROPN
dti-1548	137	1	9.6655	9.6655	NUM
dti-1548	137	2	2.9833	2.9833	NUM
dti-1548	137	3	0.040	0.040	NUM
dti-1548	137	4	*	*	PUNCT
dti-1548	137	5	akt1	akt1	PROPN
dti-1548	137	6	2.3142	2.3142	NUM
dti-1548	137	7	−1.394	−1.394	NOUN
dti-1548	137	8	0.024	0.024	NUM
dti-1548	137	9	*	*	NOUN
dti-1548	137	10	fbp1	fbp1	PROPN
dti-1548	137	11	2.1679	2.1679	NUM
dti-1548	137	12	−2.1895	−2.1895	NUM
dti-1548	137	13	0.007	0.007	NUM
dti-1548	137	14	*	*	PUNCT
dti-1548	137	15	hcc	hcc	NOUN
dti-1548	137	16	=	=	NOUN
dti-1548	137	17	hepatocellular	hepatocellular	ADJ
dti-1548	137	18	carcinoma	carcinoma	NOUN
dti-1548	137	19	.	.	PUNCT
dti-1548	138	1	p	p	X
dti-1548	139	1	=	=	PUNCT
dti-1548	139	2	p	p	NOUN
dti-1548	139	3	values	value	NOUN
dti-1548	139	4	for	for	ADP
dti-1548	139	5	mann	mann	PROPN
dti-1548	139	6	-	-	PUNCT
dti-1548	139	7	whitney	whitney	PROPN
dti-1548	139	8	test	test	NOUN
dti-1548	139	9	for	for	ADP
dti-1548	139	10	comparing	compare	VERB
dti-1548	139	11	between	between	ADP
dti-1548	139	12	the	the	DET
dti-1548	139	13	two	two	NUM
dti-1548	139	14	categories	category	NOUN
dti-1548	139	15	.	.	PUNCT
dti-1548	140	1	*	*	PUNCT
dti-1548	140	2	statistically	statistically	ADV
dti-1548	140	3	significant	significant	ADJ
dti-1548	140	4	at	at	ADP
dti-1548	140	5	p	p	NOUN
dti-1548	140	6	≤	≤	NUM
dti-1548	140	7	0.05	0.05	NUM
dti-1548	140	8	.	.	PUNCT
dti-1548	141	1	table	table	NOUN
dti-1548	141	2	xiii	xiii	PROPN
dti-1548	141	3	differentially	differentially	ADV
dti-1548	141	4	expressed	express	VERB
dti-1548	141	5	genes	gene	NOUN
dti-1548	141	6	between	between	ADP
dti-1548	141	7	hcc	hcc	PROPN
dti-1548	141	8	tumors	tumor	NOUN
dti-1548	141	9	with	with	ADP
dti-1548	141	10	clear	clear	ADJ
dti-1548	141	11	cells	cell	NOUN
dti-1548	141	12	and	and	CCONJ
dti-1548	141	13	those	those	PRON
dti-1548	141	14	without	without	ADP
dti-1548	141	15	as	as	SCONJ
dti-1548	141	16	regards	regard	VERB
dti-1548	141	17	human	human	ADJ
dti-1548	141	18	insulin	insulin	NOUN
dti-1548	141	19	signaling	signal	VERB
dti-1548	141	20	pathway	pathway	NOUN
dti-1548	141	21	gene	gene	NOUN
dti-1548	141	22	expression	expression	NOUN
dti-1548	141	23	levels	level	NOUN
dti-1548	141	24	clear	clear	ADJ
dti-1548	141	25	cells	cell	NOUN
dti-1548	141	26	p	p	NOUN
dti-1548	141	27	absent	absent	ADJ
dti-1548	141	28	(	(	PUNCT
dti-1548	141	29	n	n	NOUN
dti-1548	141	30	=	=	SYM
dti-1548	141	31	17	17	NUM
dti-1548	141	32	)	)	PUNCT
dti-1548	141	33	present	present	NOUN
dti-1548	141	34	(	(	PUNCT
dti-1548	141	35	n	n	NOUN
dti-1548	141	36	=	=	SYM
dti-1548	141	37	15	15	NUM
dti-1548	141	38	)	)	PUNCT
dti-1548	142	1	cebpb	cebpb	NOUN
dti-1548	142	2	−2.34	−2.34	PROPN
dti-1548	142	3	−12.28	−12.28	NOUN
dti-1548	142	4	0.010	0.010	NUM
dti-1548	142	5	*	*	NOUN
dti-1548	142	6	gpd1	gpd1	NOUN
dti-1548	142	7	−1.29	−1.29	NOUN
dti-1548	142	8	−2.64	−2.64	NOUN
dti-1548	142	9	0.040	0.040	NUM
dti-1548	142	10	*	*	PUNCT
dti-1548	142	11	hk2	hk2	PROPN
dti-1548	142	12	−6.14	−6.14	PRON
dti-1548	142	13	−18.17	−18.17	NOUN
dti-1548	143	1	0.050	0.050	NUM
dti-1548	143	2	*	*	PUNCT
dti-1548	143	3	igfbp1	igfbp1	NOUN
dti-1548	143	4	1.22	1.22	NUM
dti-1548	144	1	−3.46	−3.46	ADP
dti-1548	144	2	0.041	0.041	NUM
dti-1548	144	3	*	*	PUNCT
dti-1548	145	1	pik3r2	pik3r2	ADV
dti-1548	145	2	−1.41	−1.41	X
dti-1548	146	1	−6.52	−6.52	ADV
dti-1548	146	2	0.021	0.021	NUM
dti-1548	146	3	*	*	NOUN
dti-1548	146	4	hcc	hcc	PROPN
dti-1548	146	5	=	=	NOUN
dti-1548	146	6	hepatocellular	hepatocellular	ADJ
dti-1548	146	7	carcinoma	carcinoma	NOUN
dti-1548	146	8	.	.	PUNCT
dti-1548	147	1	p	p	X
dti-1548	148	1	=	=	PUNCT
dti-1548	148	2	p	p	NOUN
dti-1548	148	3	values	value	NOUN
dti-1548	148	4	for	for	ADP
dti-1548	148	5	mann	mann	PROPN
dti-1548	148	6	-	-	PUNCT
dti-1548	148	7	whitney	whitney	PROPN
dti-1548	148	8	test	test	NOUN
dti-1548	148	9	for	for	ADP
dti-1548	148	10	comparing	compare	VERB
dti-1548	148	11	between	between	ADP
dti-1548	148	12	the	the	DET
dti-1548	148	13	two	two	NUM
dti-1548	148	14	categories	category	NOUN
dti-1548	148	15	.	.	PUNCT
dti-1548	149	1	*	*	PUNCT
dti-1548	149	2	statistically	statistically	ADV
dti-1548	149	3	significant	significant	ADJ
dti-1548	149	4	at	at	ADP
dti-1548	149	5	p	p	NOUN
dti-1548	149	6	≤	≤	NUM
dti-1548	149	7	0.05	0.05	NUM
dti-1548	149	8	.	.	PUNCT
dti-1548	150	1	tumor	tumor	NOUN
dti-1548	150	2	size	size	NOUN
dti-1548	150	3	:	:	PUNCT
dti-1548	150	4	both	both	DET
dti-1548	150	5	cebpb	cebpb	NOUN
dti-1548	150	6	(	(	PUNCT
dti-1548	150	7	p	p	X
dti-1548	150	8	=	=	NOUN
dti-1548	150	9	0.027	0.027	NUM
dti-1548	150	10	)	)	PUNCT
dti-1548	150	11	and	and	CCONJ
dti-1548	150	12	gpd1	gpd1	NOUN
dti-1548	150	13	(	(	PUNCT
dti-1548	150	14	p	p	X
dti-1548	150	15	=	=	NOUN
dti-1548	150	16	0.002	0.002	NUM
dti-1548	150	17	)	)	PUNCT
dti-1548	150	18	were	be	AUX
dti-1548	150	19	significantly	significantly	ADV
dti-1548	150	20	downregulated	downregulate	VERB
dti-1548	150	21	in	in	ADP
dti-1548	150	22	tumors	tumor	NOUN
dti-1548	150	23	>	>	X
dti-1548	150	24	5	5	NUM
dti-1548	150	25	cm	cm	NOUN
dti-1548	150	26	.	.	PUNCT
dti-1548	151	1	dysplastic	dysplastic	ADJ
dti-1548	151	2	nodules	nodule	NOUN
dti-1548	151	3	:	:	PUNCT
dti-1548	151	4	no	no	DET
dti-1548	151	5	statistically	statistically	ADV
dti-1548	151	6	significant	significant	ADJ
dti-1548	151	7	difference	difference	NOUN
dti-1548	151	8	was	be	AUX
dti-1548	151	9	detected	detect	VERB
dti-1548	151	10	in	in	ADP
dti-1548	151	11	the	the	DET
dti-1548	151	12	gene	gene	NOUN
dti-1548	151	13	expression	expression	NOUN
dti-1548	151	14	levels	level	NOUN
dti-1548	151	15	of	of	ADP
dti-1548	151	16	any	any	DET
dti-1548	151	17	genes	gene	NOUN
dti-1548	151	18	between	between	ADP
dti-1548	151	19	cases	case	NOUN
dti-1548	151	20	who	who	PRON
dti-1548	151	21	had	have	VERB
dti-1548	151	22	dysplastic	dysplastic	ADJ
dti-1548	151	23	nodules	nodule	NOUN
dti-1548	151	24	outside	outside	ADP
dti-1548	151	25	tumor	tumor	NOUN
dti-1548	151	26	mass	mass	NOUN
dti-1548	151	27	and	and	CCONJ
dti-1548	151	28	those	those	PRON
dti-1548	151	29	who	who	PRON
dti-1548	151	30	did	do	AUX
dti-1548	151	31	not	not	PART
dti-1548	151	32	have	have	VERB
dti-1548	151	33	any	any	PRON
dti-1548	151	34	(	(	PUNCT
dti-1548	151	35	none	none	NOUN
dti-1548	151	36	were	be	AUX
dti-1548	151	37	<	<	X
dti-1548	151	38	0.05	0.05	NUM
dti-1548	151	39	)	)	PUNCT
dti-1548	151	40	.	.	PUNCT
dti-1548	152	1	satellite	satellite	NOUN
dti-1548	152	2	nodules	nodule	NOUN
dti-1548	152	3	:	:	PUNCT
dti-1548	152	4	aebp1	aebp1	NOUN
dti-1548	152	5	and	and	CCONJ
dti-1548	152	6	fos	fos	VERB
dti-1548	152	7	genes	gene	NOUN
dti-1548	152	8	were	be	AUX
dti-1548	152	9	upregulated	upregulate	VERB
dti-1548	152	10	in	in	ADP
dti-1548	152	11	the	the	DET
dti-1548	152	12	absence	absence	NOUN
dti-1548	152	13	of	of	ADP
dti-1548	152	14	satellite	satellite	NOUN
dti-1548	152	15	nodules	nodule	NOUN
dti-1548	152	16	more	more	ADV
dti-1548	152	17	than	than	ADP
dti-1548	152	18	double	double	ADJ
dti-1548	152	19	their	their	PRON
dti-1548	152	20	expression	expression	NOUN
dti-1548	152	21	level	level	NOUN
dti-1548	152	22	in	in	ADP
dti-1548	152	23	the	the	DET
dti-1548	152	24	cases	case	NOUN
dti-1548	152	25	which	which	PRON
dti-1548	152	26	showed	show	VERB
dti-1548	152	27	satellite	satellite	NOUN
dti-1548	152	28	nodules	nodule	NOUN
dti-1548	152	29	.	.	PUNCT
dti-1548	153	1	mapk1	mapk1	NOUN
dti-1548	153	2	gene	gene	NOUN
dti-1548	153	3	was	be	AUX
dti-1548	153	4	overexpressed	overexpresse	VERB
dti-1548	153	5	in	in	ADP
dti-1548	153	6	the	the	DET
dti-1548	153	7	presence	presence	NOUN
dti-1548	153	8	of	of	ADP
dti-1548	153	9	satellite	satellite	NOUN
dti-1548	153	10	nodules	nodule	NOUN
dti-1548	153	11	and	and	CCONJ
dti-1548	153	12	normally	normally	ADV
dti-1548	153	13	expressed	express	VERB
dti-1548	153	14	in	in	ADP
dti-1548	153	15	their	their	PRON
dti-1548	153	16	absence	absence	NOUN
dti-1548	153	17	.	.	PUNCT
dti-1548	154	1	prkcz	prkcz	PROPN
dti-1548	154	2	and	and	CCONJ
dti-1548	154	3	ucp1	ucp1	ADJ
dti-1548	154	4	genes	gene	NOUN
dti-1548	154	5	were	be	AUX
dti-1548	154	6	downregulated	downregulate	VERB
dti-1548	154	7	in	in	ADP
dti-1548	154	8	the	the	DET
dti-1548	154	9	absence	absence	NOUN
dti-1548	154	10	of	of	ADP
dti-1548	154	11	satellite	satellite	NOUN
dti-1548	154	12	nodules	nodule	NOUN
dti-1548	154	13	and	and	CCONJ
dti-1548	154	14	normally	normally	ADV
dti-1548	154	15	expressed	express	VERB
dti-1548	154	16	in	in	ADP
dti-1548	154	17	their	their	PRON
dti-1548	154	18	presence	presence	NOUN
dti-1548	154	19	(	(	PUNCT
dti-1548	154	20	tab	tab	NOUN
dti-1548	154	21	.	.	PUNCT
dti-1548	155	1	xi	xi	PROPN
dti-1548	155	2	)	)	PUNCT
dti-1548	155	3	.	.	PUNCT
dti-1548	156	1	multifocality	multifocality	NOUN
dti-1548	156	2	:	:	PUNCT
dti-1548	157	1	aebp1	aebp1	PROPN
dti-1548	157	2	and	and	CCONJ
dti-1548	157	3	fos	fos	VERB
dti-1548	157	4	genes	gene	NOUN
dti-1548	157	5	were	be	AUX
dti-1548	157	6	upregulated	upregulate	VERB
dti-1548	157	7	in	in	ADP
dti-1548	157	8	the	the	DET
dti-1548	157	9	absence	absence	NOUN
dti-1548	157	10	of	of	ADP
dti-1548	157	11	multifocal	multifocal	ADJ
dti-1548	157	12	masses	masse	NOUN
dti-1548	157	13	more	more	ADV
dti-1548	157	14	than	than	ADP
dti-1548	157	15	double	double	VERB
dti-1548	157	16	their	their	PRON
dti-1548	157	17	expression	expression	NOUN
dti-1548	157	18	level	level	NOUN
dti-1548	157	19	in	in	ADP
dti-1548	157	20	the	the	DET
dti-1548	157	21	cases	case	NOUN
dti-1548	157	22	which	which	PRON
dti-1548	157	23	showed	show	VERB
dti-1548	157	24	multifocal	multifocal	ADJ
dti-1548	157	25	masses	masse	NOUN
dti-1548	157	26	.	.	PUNCT
dti-1548	158	1	ldlr	ldlr	ADJ
dti-1548	158	2	gene	gene	NOUN
dti-1548	158	3	was	be	AUX
dti-1548	158	4	overexpressed	overexpresse	VERB
dti-1548	158	5	in	in	ADP
dti-1548	158	6	the	the	DET
dti-1548	158	7	absence	absence	NOUN
dti-1548	158	8	of	of	ADP
dti-1548	158	9	multifocal	multifocal	ADJ
dti-1548	158	10	masses	masse	NOUN
dti-1548	158	11	and	and	CCONJ
dti-1548	158	12	normally	normally	ADV
dti-1548	158	13	expressed	express	VERB
dti-1548	158	14	in	in	ADP
dti-1548	158	15	their	their	PRON
dti-1548	158	16	presence	presence	NOUN
dti-1548	158	17	(	(	PUNCT
dti-1548	158	18	tab	tab	NOUN
dti-1548	158	19	.	.	PUNCT
dti-1548	159	1	xii	xii	PROPN
dti-1548	159	2	)	)	PUNCT
dti-1548	159	3	.	.	PUNCT
dti-1548	160	1	gross	gross	ADJ
dti-1548	160	2	capsulation	capsulation	NOUN
dti-1548	160	3	:	:	PUNCT
dti-1548	160	4	both	both	DET
dti-1548	160	5	insl3	insl3	PROPN
dti-1548	160	6	(	(	PUNCT
dti-1548	160	7	p	p	X
dti-1548	160	8	=	=	NOUN
dti-1548	160	9	0.043	0.043	NUM
dti-1548	160	10	)	)	PUNCT
dti-1548	160	11	and	and	CCONJ
dti-1548	160	12	irs1	irs1	NOUN
dti-1548	160	13	(	(	PUNCT
dti-1548	160	14	p	p	X
dti-1548	160	15	=	=	NOUN
dti-1548	160	16	0.030	0.030	NUM
dti-1548	160	17	)	)	PUNCT
dti-1548	160	18	genes	gene	NOUN
dti-1548	160	19	were	be	AUX
dti-1548	160	20	downregulated	downregulate	VERB
dti-1548	160	21	in	in	ADP
dti-1548	160	22	the	the	DET
dti-1548	160	23	presence	presence	NOUN
dti-1548	160	24	of	of	ADP
dti-1548	160	25	gross	gross	ADJ
dti-1548	160	26	capsulation	capsulation	NOUN
dti-1548	160	27	.	.	PUNCT
dti-1548	161	1	gross	gross	ADJ
dti-1548	161	2	tumor	tumor	NOUN
dti-1548	161	3	necrosis	necrosis	NOUN
dti-1548	161	4	:	:	PUNCT
dti-1548	161	5	cap1	cap1	NOUN
dti-1548	161	6	(	(	PUNCT
dti-1548	161	7	p	p	X
dti-1548	161	8	=	=	NOUN
dti-1548	161	9	0.041	0.041	NUM
dti-1548	161	10	)	)	PUNCT
dti-1548	161	11	,	,	PUNCT
dti-1548	161	12	grb2	grb2	PROPN
dti-1548	161	13	(	(	PUNCT
dti-1548	161	14	p	p	X
dti-1548	161	15	=	=	NOUN
dti-1548	161	16	0.047	0.047	NUM
dti-1548	161	17	)	)	PUNCT
dti-1548	161	18	,	,	PUNCT
dti-1548	161	19	prl	prl	X
dti-1548	161	20	(	(	PUNCT
dti-1548	161	21	p	p	NOUN
dti-1548	161	22	=	=	NOUN
dti-1548	161	23	0.024	0.024	NUM
dti-1548	161	24	)	)	PUNCT
dti-1548	161	25	,	,	PUNCT
dti-1548	161	26	and	and	CCONJ
dti-1548	161	27	tg	tg	INTJ
dti-1548	161	28	(	(	PUNCT
dti-1548	161	29	p	p	X
dti-1548	161	30	=	=	NOUN
dti-1548	161	31	0.025	0.025	NUM
dti-1548	161	32	)	)	PUNCT
dti-1548	161	33	were	be	AUX
dti-1548	161	34	downregulated	downregulate	VERB
dti-1548	161	35	in	in	ADP
dti-1548	161	36	the	the	DET
dti-1548	161	37	presence	presence	NOUN
dti-1548	161	38	of	of	ADP
dti-1548	161	39	gross	gross	ADJ
dti-1548	161	40	necrosis	necrosis	NOUN
dti-1548	161	41	.	.	PUNCT
dti-1548	162	1	pik3r1	pik3r1	NOUN
dti-1548	162	2	(	(	PUNCT
dti-1548	162	3	p	p	X
dti-1548	162	4	=	=	NOUN
dti-1548	162	5	0.016	0.016	NUM
dti-1548	162	6	)	)	PUNCT
dti-1548	162	7	was	be	AUX
dti-1548	162	8	upregulated	upregulate	VERB
dti-1548	162	9	in	in	ADP
dti-1548	162	10	the	the	DET
dti-1548	162	11	absence	absence	NOUN
dti-1548	162	12	of	of	ADP
dti-1548	162	13	gross	gross	ADJ
dti-1548	162	14	tumor	tumor	NOUN
dti-1548	162	15	necrosis	necrosis	NOUN
dti-1548	162	16	.	.	PUNCT
dti-1548	163	1	giant	giant	ADJ
dti-1548	163	2	cells	cell	NOUN
dti-1548	163	3	:	:	PUNCT
dti-1548	163	4	both	both	DET
dti-1548	163	5	gsk3a	gsk3a	PROPN
dti-1548	163	6	(	(	PUNCT
dti-1548	163	7	p	p	X
dti-1548	163	8	=	=	NOUN
dti-1548	163	9	0.015	0.015	NUM
dti-1548	163	10	)	)	PUNCT
dti-1548	163	11	and	and	CCONJ
dti-1548	163	12	pck2	pck2	PROPN
dti-1548	163	13	(	(	PUNCT
dti-1548	163	14	p	p	X
dti-1548	163	15	=	=	NOUN
dti-1548	163	16	0.030	0.030	NUM
dti-1548	163	17	)	)	PUNCT
dti-1548	163	18	were	be	AUX
dti-1548	163	19	upregulated	upregulate	VERB
dti-1548	163	20	in	in	ADP
dti-1548	163	21	the	the	DET
dti-1548	163	22	absence	absence	NOUN
dti-1548	163	23	of	of	ADP
dti-1548	163	24	giant	giant	ADJ
dti-1548	163	25	cells	cell	NOUN
dti-1548	163	26	.	.	PUNCT
dti-1548	164	1	ucp1	ucp1	PROPN
dti-1548	164	2	(	(	PUNCT
dti-1548	164	3	p	p	X
dti-1548	164	4	=	=	NOUN
dti-1548	164	5	0.033	0.033	NUM
dti-1548	164	6	)	)	PUNCT
dti-1548	164	7	was	be	AUX
dti-1548	164	8	downregulated	downregulate	VERB
dti-1548	164	9	in	in	ADP
dti-1548	164	10	tumors	tumor	NOUN
dti-1548	164	11	that	that	PRON
dti-1548	164	12	showed	show	VERB
dti-1548	164	13	giant	giant	ADJ
dti-1548	164	14	cells	cell	NOUN
dti-1548	164	15	.	.	PUNCT
dti-1548	165	1	clear	clear	ADJ
dti-1548	165	2	cells	cell	NOUN
dti-1548	165	3	:	:	PUNCT
dti-1548	165	4	cebpb	cebpb	NOUN
dti-1548	165	5	,	,	PUNCT
dti-1548	165	6	hk2	hk2	PROPN
dti-1548	165	7	,	,	PUNCT
dti-1548	165	8	gpd1	gpd1	NOUN
dti-1548	165	9	,	,	PUNCT
dti-1548	165	10	igfbp1	igfbp1	PROPN
dti-1548	165	11	and	and	CCONJ
dti-1548	165	12	pik3r2	pik3r2	ADV
dti-1548	165	13	were	be	AUX
dti-1548	165	14	downregulated	downregulate	VERB
dti-1548	165	15	in	in	ADP
dti-1548	165	16	all	all	DET
dti-1548	165	17	the	the	DET
dti-1548	165	18	studied	studied	ADJ
dti-1548	165	19	cases	case	NOUN
dti-1548	165	20	,	,	PUNCT
dti-1548	165	21	more	more	ADV
dti-1548	165	22	so	so	ADV
dti-1548	165	23	in	in	ADP
dti-1548	165	24	tumors	tumor	NOUN
dti-1548	165	25	that	that	PRON
dti-1548	165	26	showed	show	VERB
dti-1548	165	27	clear	clear	ADJ
dti-1548	165	28	cells	cell	NOUN
dti-1548	165	29	than	than	ADP
dti-1548	165	30	in	in	ADP
dti-1548	165	31	tumors	tumor	NOUN
dti-1548	165	32	which	which	PRON
dti-1548	165	33	had	have	VERB
dti-1548	165	34	no	no	DET
dti-1548	165	35	clear	clear	ADJ
dti-1548	165	36	cells	cell	NOUN
dti-1548	165	37	(	(	PUNCT
dti-1548	165	38	tab	tab	NOUN
dti-1548	165	39	.	.	PUNCT
dti-1548	165	40	xiii	xiii	PROPN
dti-1548	165	41	)	)	PUNCT
dti-1548	165	42	.	.	PUNCT
dti-1548	166	1	vascular	vascular	ADJ
dti-1548	166	2	invasion	invasion	NOUN
dti-1548	166	3	:	:	PUNCT
dti-1548	166	4	nos2	nos2	PROPN
dti-1548	166	5	showed	show	VERB
dti-1548	166	6	more	more	ADV
dti-1548	166	7	significant	significant	ADJ
dti-1548	166	8	downregulation	downregulation	NOUN
dti-1548	166	9	in	in	ADP
dti-1548	166	10	the	the	DET
dti-1548	166	11	absence	absence	NOUN
dti-1548	166	12	of	of	ADP
dti-1548	166	13	vascular	vascular	ADJ
dti-1548	166	14	invasion	invasion	NOUN
dti-1548	166	15	(	(	PUNCT
dti-1548	166	16	p	p	X
dti-1548	166	17	=	=	NOUN
dti-1548	166	18	0.035	0.035	NUM
dti-1548	166	19	)	)	PUNCT
dti-1548	166	20	.	.	PUNCT
dti-1548	167	1	hbcag	hbcag	PROPN
dti-1548	167	2	:	:	PUNCT
dti-1548	168	1	rps6ka1	rps6ka1	PROPN
dti-1548	168	2	was	be	AUX
dti-1548	168	3	more	more	ADV
dti-1548	168	4	significantly	significantly	ADV
dti-1548	168	5	underexpressed	underexpressed	ADJ
dti-1548	168	6	in	in	ADP
dti-1548	168	7	the	the	DET
dti-1548	168	8	presence	presence	NOUN
dti-1548	168	9	of	of	ADP
dti-1548	168	10	hbcag	hbcag	PROPN
dti-1548	168	11	(	(	PUNCT
dti-1548	168	12	p	p	X
dti-1548	168	13	=	=	NOUN
dti-1548	168	14	0.034	0.034	NUM
dti-1548	168	15	)	)	PUNCT
dti-1548	168	16	.	.	PUNCT
dti-1548	169	1	afb1	afb1	PROPN
dti-1548	169	2	-	-	PUNCT
dti-1548	169	3	dna	dna	PROPN
dti-1548	169	4	adduct	adduct	NOUN
dti-1548	169	5	positivity	positivity	NOUN
dti-1548	169	6	:	:	PUNCT
dti-1548	169	7	akt1	akt1	PROPN
dti-1548	169	8	and	and	CCONJ
dti-1548	169	9	mapk1	mapk1	NOUN
dti-1548	169	10	were	be	AUX
dti-1548	169	11	more	more	ADV
dti-1548	169	12	significantly	significantly	ADV
dti-1548	169	13	upregulated	upregulate	VERB
dti-1548	169	14	in	in	ADP
dti-1548	169	15	the	the	DET
dti-1548	169	16	presence	presence	NOUN
dti-1548	169	17	of	of	ADP
dti-1548	169	18	aflatoxin	aflatoxin	NOUN
dti-1548	169	19	as	as	ADP
dti-1548	169	20	compared	compare	VERB
dti-1548	169	21	to	to	ADP
dti-1548	169	22	negative	negative	ADJ
dti-1548	169	23	cases	case	NOUN
dti-1548	169	24	(	(	PUNCT
dti-1548	169	25	p	p	X
dti-1548	169	26	=	=	NOUN
dti-1548	169	27	0.019	0.019	NUM
dti-1548	169	28	,	,	PUNCT
dti-1548	169	29	0.017	0.017	NUM
dti-1548	169	30	respectively	respectively	ADV
dti-1548	169	31	)	)	PUNCT
dti-1548	169	32	.	.	PUNCT
dti-1548	170	1	on	on	ADP
dti-1548	170	2	the	the	DET
dti-1548	170	3	other	other	ADJ
dti-1548	170	4	hand	hand	NOUN
dti-1548	170	5	,	,	PUNCT
dti-1548	170	6	rps6ka1	rps6ka1	PROPN
dti-1548	170	7	was	be	AUX
dti-1548	170	8	more	more	ADV
dti-1548	170	9	significantly	significantly	ADV
dti-1548	170	10	underexpressed	underexpressed	ADJ
dti-1548	170	11	in	in	ADP
dti-1548	170	12	the	the	DET
dti-1548	170	13	presence	presence	NOUN
dti-1548	170	14	of	of	ADP
dti-1548	170	15	afb1	afb1	PROPN
dti-1548	170	16	(	(	PUNCT
dti-1548	170	17	p	p	X
dti-1548	170	18	=	=	PROPN
dti-1548	170	19	0.046	0.046	NUM
dti-1548	170	20	)	)	PUNCT
dti-1548	170	21	.	.	PUNCT
dti-1548	171	1	correlations	correlation	NOUN
dti-1548	171	2	between	between	ADP
dti-1548	171	3	the	the	DET
dti-1548	171	4	gene	gene	NOUN
dti-1548	171	5	expression	expression	NOUN
dti-1548	171	6	levels	level	NOUN
dti-1548	171	7	and	and	CCONJ
dti-1548	171	8	the	the	DET
dti-1548	171	9	different	different	ADJ
dti-1548	171	10	clinical	clinical	ADJ
dti-1548	171	11	characteristics	characteristic	NOUN
dti-1548	171	12	of	of	ADP
dti-1548	171	13	the	the	DET
dti-1548	171	14	tumors	tumor	NOUN
dti-1548	171	15	in	in	ADP
dti-1548	171	16	hcc	hcc	PROPN
dti-1548	171	17	patients	patient	NOUN
dti-1548	171	18	thrombocytopenia	thrombocytopenia	PROPN
dti-1548	171	19	:	:	PUNCT
dti-1548	171	20	in	in	ADP
dti-1548	171	21	patients	patient	NOUN
dti-1548	171	22	with	with	ADP
dti-1548	171	23	a	a	DET
dti-1548	171	24	low	low	ADJ
dti-1548	171	25	platelet	platelet	NOUN
dti-1548	171	26	count	count	NOUN
dti-1548	171	27	,	,	PUNCT
dti-1548	171	28	akt1	akt1	PROPN
dti-1548	171	29	was	be	AUX
dti-1548	171	30	significantly	significantly	ADV
dti-1548	171	31	upregulated	upregulate	VERB
dti-1548	171	32	(	(	PUNCT
dti-1548	171	33	p	p	X
dti-1548	171	34	=	=	NOUN
dti-1548	171	35	0.038	0.038	NUM
dti-1548	171	36	)	)	PUNCT
dti-1548	171	37	while	while	SCONJ
dti-1548	171	38	bcl2l1	bcl2l1	NOUN
dti-1548	171	39	table	table	NOUN
dti-1548	171	40	xi	xi	X
dti-1548	171	41	differentially	differentially	ADV
dti-1548	171	42	expressed	express	VERB
dti-1548	171	43	genes	gene	NOUN
dti-1548	171	44	between	between	ADP
dti-1548	171	45	hcc	hcc	PROPN
dti-1548	171	46	cases	case	NOUN
dti-1548	171	47	having	have	VERB
dti-1548	171	48	satellite	satellite	NOUN
dti-1548	171	49	nodules	nodule	NOUN
dti-1548	171	50	around	around	ADP
dti-1548	171	51	the	the	DET
dti-1548	171	52	tumor	tumor	NOUN
dti-1548	171	53	mass	mass	NOUN
dti-1548	171	54	and	and	CCONJ
dti-1548	171	55	those	those	PRON
dti-1548	171	56	without	without	ADP
dti-1548	171	57	,	,	PUNCT
dti-1548	171	58	as	as	SCONJ
dti-1548	171	59	regards	regard	VERB
dti-1548	171	60	human	human	ADJ
dti-1548	171	61	insulin	insulin	NOUN
dti-1548	171	62	signaling	signal	VERB
dti-1548	171	63	pathway	pathway	NOUN
dti-1548	171	64	gene	gene	NOUN
dti-1548	171	65	expression	expression	NOUN
dti-1548	171	66	levels	level	NOUN
dti-1548	171	67	satellite	satellite	NOUN
dti-1548	171	68	nodules	nodule	NOUN
dti-1548	171	69	p	p	NOUN
dti-1548	171	70	absent	absent	ADJ
dti-1548	171	71	(	(	PUNCT
dti-1548	171	72	n	n	NOUN
dti-1548	171	73	=	=	SYM
dti-1548	171	74	6	6	NUM
dti-1548	171	75	)	)	PUNCT
dti-1548	171	76	present	present	NOUN
dti-1548	171	77	(	(	PUNCT
dti-1548	171	78	n	n	NOUN
dti-1548	171	79	=	=	SYM
dti-1548	171	80	26	26	NUM
dti-1548	171	81	)	)	PUNCT
dti-1548	171	82	aebp1	aebp1	NOUN
dti-1548	171	83	17.44	17.44	NUM
dti-1548	171	84	5.37	5.37	NUM
dti-1548	171	85	0.004	0.004	NUM
dti-1548	171	86	*	*	PUNCT
dti-1548	171	87	fos	fo	VERB
dti-1548	171	88	13.21	13.21	NUM
dti-1548	171	89	3.00	3.00	NUM
dti-1548	171	90	0.007	0.007	NUM
dti-1548	171	91	*	*	PUNCT
dti-1548	171	92	mapk1	mapk1	NOUN
dti-1548	171	93	−1.97	−1.97	ADP
dti-1548	171	94	2.05	2.05	NUM
dti-1548	171	95	0.012	0.012	NUM
dti-1548	171	96	*	*	PUNCT
dti-1548	171	97	prkcz	prkcz	NOUN
dti-1548	171	98	−2.63	−2.63	PRON
dti-1548	171	99	1.42	1.42	NUM
dti-1548	171	100	0.026	0.026	NUM
dti-1548	171	101	*	*	PUNCT
dti-1548	171	102	ucp1	ucp1	PROPN
dti-1548	171	103	−9.60	−9.60	PROPN
dti-1548	172	1	−1.98	−1.98	ADV
dti-1548	172	2	0.014	0.014	NUM
dti-1548	172	3	*	*	NOUN
dti-1548	172	4	hcc	hcc	NOUN
dti-1548	172	5	=	=	NOUN
dti-1548	172	6	hepatocellular	hepatocellular	ADJ
dti-1548	172	7	carcinoma	carcinoma	NOUN
dti-1548	172	8	.	.	PUNCT
dti-1548	173	1	p	p	X
dti-1548	174	1	=	=	PUNCT
dti-1548	174	2	p	p	NOUN
dti-1548	174	3	values	value	NOUN
dti-1548	174	4	for	for	ADP
dti-1548	174	5	mann	mann	PROPN
dti-1548	174	6	-	-	PUNCT
dti-1548	174	7	whitney	whitney	PROPN
dti-1548	174	8	test	test	NOUN
dti-1548	174	9	for	for	ADP
dti-1548	174	10	comparing	compare	VERB
dti-1548	174	11	between	between	ADP
dti-1548	174	12	the	the	DET
dti-1548	174	13	two	two	NUM
dti-1548	174	14	categories	category	NOUN
dti-1548	174	15	.	.	PUNCT
dti-1548	175	1	*	*	PUNCT
dti-1548	175	2	statistically	statistically	ADV
dti-1548	175	3	significant	significant	ADJ
dti-1548	175	4	at	at	ADP
dti-1548	175	5	p	p	NOUN
dti-1548	175	6	≤	≤	NUM
dti-1548	175	7	0.05	0.05	NUM
dti-1548	175	8	.	.	PUNCT
dti-1548	176	1	table	table	NOUN
dti-1548	176	2	xii	xii	PROPN
dti-1548	176	3	differentially	differentially	ADV
dti-1548	176	4	expressed	express	VERB
dti-1548	176	5	genes	gene	NOUN
dti-1548	176	6	between	between	ADP
dti-1548	176	7	hcc	hcc	PROPN
dti-1548	176	8	cases	case	NOUN
dti-1548	176	9	having	have	VERB
dti-1548	176	10	multifocal	multifocal	ADJ
dti-1548	176	11	tumor	tumor	NOUN
dti-1548	176	12	masses	masse	NOUN
dti-1548	176	13	and	and	CCONJ
dti-1548	176	14	those	those	PRON
dti-1548	176	15	with	with	ADP
dti-1548	176	16	unifocal	unifocal	ADJ
dti-1548	176	17	masses	masse	NOUN
dti-1548	176	18	as	as	SCONJ
dti-1548	176	19	regards	regard	VERB
dti-1548	176	20	human	human	ADJ
dti-1548	176	21	insulin	insulin	NOUN
dti-1548	176	22	signaling	signal	VERB
dti-1548	176	23	pathway	pathway	NOUN
dti-1548	176	24	gene	gene	NOUN
dti-1548	176	25	expression	expression	NOUN
dti-1548	176	26	levels	level	NOUN
dti-1548	176	27	multifocality	multifocality	NOUN
dti-1548	176	28	p	p	NOUN
dti-1548	176	29	absent	absent	ADJ
dti-1548	176	30	(	(	PUNCT
dti-1548	176	31	n	n	NOUN
dti-1548	176	32	=	=	SYM
dti-1548	176	33	4	4	NUM
dti-1548	176	34	)	)	PUNCT
dti-1548	176	35	present	present	NOUN
dti-1548	176	36	(	(	PUNCT
dti-1548	176	37	n	n	NOUN
dti-1548	176	38	=	=	SYM
dti-1548	176	39	28	28	NUM
dti-1548	176	40	)	)	PUNCT
dti-1548	176	41	aebp1	aebp1	NOUN
dti-1548	176	42	26.30	26.30	NUM
dti-1548	176	43	5.51	5.51	NUM
dti-1548	176	44	0.004	0.004	NUM
dti-1548	176	45	*	*	PUNCT
dti-1548	176	46	fos	fo	VERB
dti-1548	176	47	19.81	19.81	NUM
dti-1548	176	48	3.15	3.15	NUM
dti-1548	176	49	0.003	0.003	NUM
dti-1548	176	50	*	*	PUNCT
dti-1548	176	51	ldlr	ldlr	PROPN
dti-1548	176	52	7.12	7.12	NUM
dti-1548	176	53	1.88	1.88	NUM
dti-1548	176	54	0.035	0.035	NUM
dti-1548	176	55	*	*	PUNCT
dti-1548	176	56	hcc	hcc	NOUN
dti-1548	176	57	=	=	NOUN
dti-1548	176	58	hepatocellular	hepatocellular	ADJ
dti-1548	176	59	carcinoma	carcinoma	NOUN
dti-1548	176	60	.	.	PUNCT
dti-1548	177	1	p	p	X
dti-1548	178	1	=	=	PUNCT
dti-1548	178	2	p	p	NOUN
dti-1548	178	3	values	value	NOUN
dti-1548	178	4	for	for	ADP
dti-1548	178	5	mann	mann	PROPN
dti-1548	178	6	-	-	PUNCT
dti-1548	178	7	whitney	whitney	PROPN
dti-1548	178	8	test	test	NOUN
dti-1548	178	9	for	for	ADP
dti-1548	178	10	comparing	compare	VERB
dti-1548	178	11	between	between	ADP
dti-1548	178	12	the	the	DET
dti-1548	178	13	two	two	NUM
dti-1548	178	14	categories	category	NOUN
dti-1548	178	15	.	.	PUNCT
dti-1548	179	1	*	*	PUNCT
dti-1548	179	2	statistically	statistically	ADV
dti-1548	179	3	significant	significant	ADJ
dti-1548	179	4	at	at	ADP
dti-1548	179	5	p	p	NOUN
dti-1548	179	6	≤	≤	NUM
dti-1548	179	7	0.05	0.05	NUM
dti-1548	179	8	.	.	PUNCT
dti-1548	180	1	mabrouk	mabrouk	PROPN
dti-1548	180	2	et	et	NOUN
dti-1548	180	3	al	al	PROPN
dti-1548	180	4	7	7	NUM
dti-1548	180	5	©	©	PROPN
dti-1548	180	6	2020	2020	NUM
dti-1548	180	7	the	the	DET
dti-1548	180	8	authors	author	NOUN
dti-1548	180	9	.	.	PUNCT
dti-1548	181	1	published	publish	VERB
dti-1548	181	2	by	by	ADP
dti-1548	181	3	aboutscience	aboutscience	NOUN
dti-1548	181	4	was	be	AUX
dti-1548	181	5	significantly	significantly	ADV
dti-1548	181	6	downregulated	downregulate	VERB
dti-1548	181	7	(	(	PUNCT
dti-1548	181	8	p	p	X
dti-1548	181	9	=	=	NOUN
dti-1548	181	10	0.045	0.045	NUM
dti-1548	181	11	)	)	PUNCT
dti-1548	181	12	.	.	PUNCT
dti-1548	182	1	vegfa	vegfa	PROPN
dti-1548	182	2	was	be	AUX
dti-1548	182	3	more	more	ADV
dti-1548	182	4	significantly	significantly	ADV
dti-1548	182	5	underexpressed	underexpressed	ADJ
dti-1548	182	6	in	in	ADP
dti-1548	182	7	the	the	DET
dti-1548	182	8	presence	presence	NOUN
dti-1548	182	9	of	of	ADP
dti-1548	182	10	normal	normal	ADJ
dti-1548	182	11	platelet	platelet	NOUN
dti-1548	182	12	numbers	number	NOUN
dti-1548	182	13	(	(	PUNCT
dti-1548	182	14	p	p	X
dti-1548	182	15	=	=	NOUN
dti-1548	182	16	0.038	0.038	NUM
dti-1548	182	17	)	)	PUNCT
dti-1548	182	18	.	.	PUNCT
dti-1548	183	1	comorbidities	comorbiditie	NOUN
dti-1548	183	2	:	:	PUNCT
dti-1548	183	3	there	there	PRON
dti-1548	183	4	was	be	VERB
dti-1548	183	5	no	no	DET
dti-1548	183	6	statistically	statistically	ADV
dti-1548	183	7	significant	significant	ADJ
dti-1548	183	8	difference	difference	NOUN
dti-1548	183	9	in	in	ADP
dti-1548	183	10	the	the	DET
dti-1548	183	11	gene	gene	NOUN
dti-1548	183	12	expression	expression	NOUN
dti-1548	183	13	levels	level	NOUN
dti-1548	183	14	between	between	ADP
dti-1548	183	15	patients	patient	NOUN
dti-1548	183	16	who	who	PRON
dti-1548	183	17	have	have	VERB
dti-1548	183	18	comorbidities	comorbiditie	NOUN
dti-1548	183	19	and	and	CCONJ
dti-1548	183	20	those	those	PRON
dti-1548	183	21	who	who	PRON
dti-1548	183	22	do	do	AUX
dti-1548	183	23	not	not	PART
dti-1548	183	24	have	have	VERB
dti-1548	183	25	any	any	PRON
dti-1548	183	26	.	.	PUNCT
dti-1548	184	1	canonical	canonical	ADJ
dti-1548	184	2	pathway	pathway	NOUN
dti-1548	184	3	analysis	analysis	NOUN
dti-1548	184	4	predicted	predict	VERB
dti-1548	184	5	by	by	ADP
dti-1548	184	6	ipa	ipa	PROPN
dti-1548	184	7	database	database	PROPN
dti-1548	184	8	nitric	nitric	ADJ
dti-1548	184	9	oxide	oxide	NOUN
dti-1548	184	10	and	and	CCONJ
dti-1548	184	11	reactive	reactive	ADJ
dti-1548	184	12	oxygen	oxygen	NOUN
dti-1548	184	13	species	specie	NOUN
dti-1548	184	14	production	production	NOUN
dti-1548	184	15	pathway	pathway	NOUN
dti-1548	184	16	was	be	AUX
dti-1548	184	17	significantly	significantly	ADV
dti-1548	184	18	activated	activate	VERB
dti-1548	184	19	in	in	ADP
dti-1548	184	20	the	the	DET
dti-1548	184	21	present	present	ADJ
dti-1548	184	22	cohort	cohort	NOUN
dti-1548	184	23	,	,	PUNCT
dti-1548	184	24	while	while	SCONJ
dti-1548	184	25	the	the	DET
dti-1548	184	26	growth	growth	NOUN
dti-1548	184	27	hormone	hormone	NOUN
dti-1548	184	28	signaling	signal	VERB
dti-1548	184	29	pathway	pathway	NOUN
dti-1548	184	30	was	be	AUX
dti-1548	184	31	significantly	significantly	ADV
dti-1548	184	32	inactivated	inactivated	ADJ
dti-1548	184	33	(	(	PUNCT
dti-1548	184	34	fig	fig	NOUN
dti-1548	184	35	.	.	PUNCT
dti-1548	185	1	4	4	NUM
dti-1548	185	2	)	)	PUNCT
dti-1548	185	3	.	.	PUNCT
dti-1548	186	1	discussion	discussion	NOUN
dti-1548	186	2	different	different	ADJ
dti-1548	186	3	etiologic	etiologic	ADJ
dti-1548	186	4	factors	factor	NOUN
dti-1548	186	5	result	result	VERB
dti-1548	186	6	in	in	ADP
dti-1548	186	7	very	very	ADV
dti-1548	186	8	diverse	diverse	ADJ
dti-1548	186	9	hcc	hcc	PROPN
dti-1548	186	10	molecular	molecular	ADJ
dti-1548	186	11	profiles	profile	NOUN
dti-1548	186	12	between	between	ADP
dti-1548	186	13	different	different	ADJ
dti-1548	186	14	regions	region	NOUN
dti-1548	186	15	of	of	ADP
dti-1548	186	16	the	the	DET
dti-1548	186	17	world	world	NOUN
dti-1548	186	18	(	(	PUNCT
dti-1548	186	19	13,14	13,14	NUM
dti-1548	186	20	)	)	PUNCT
dti-1548	186	21	.	.	PUNCT
dti-1548	187	1	understanding	understand	VERB
dti-1548	187	2	the	the	DET
dti-1548	187	3	heterogeneity	heterogeneity	NOUN
dti-1548	187	4	of	of	ADP
dti-1548	187	5	hcc	hcc	PROPN
dti-1548	187	6	is	be	AUX
dti-1548	187	7	conducive	conducive	ADJ
dti-1548	187	8	to	to	ADP
dti-1548	187	9	developing	develop	VERB
dti-1548	187	10	personalized	personalize	VERB
dti-1548	187	11	therapy	therapy	NOUN
dti-1548	187	12	and	and	CCONJ
dti-1548	187	13	identifying	identify	VERB
dti-1548	187	14	molecular	molecular	ADJ
dti-1548	187	15	biomarkers	biomarker	NOUN
dti-1548	187	16	.	.	PUNCT
dti-1548	188	1	most	most	ADV
dti-1548	188	2	published	publish	VERB
dti-1548	188	3	work	work	NOUN
dti-1548	188	4	on	on	ADP
dti-1548	188	5	molecular	molecular	ADJ
dti-1548	188	6	profiling	profiling	NOUN
dti-1548	188	7	of	of	ADP
dti-1548	188	8	hcc	hcc	PROPN
dti-1548	188	9	was	be	AUX
dti-1548	188	10	conducted	conduct	VERB
dti-1548	188	11	on	on	ADP
dti-1548	188	12	heterogeneous	heterogeneous	ADJ
dti-1548	188	13	groups	group	NOUN
dti-1548	188	14	of	of	ADP
dti-1548	188	15	tumors	tumor	NOUN
dti-1548	188	16	including	include	VERB
dti-1548	188	17	different	different	ADJ
dti-1548	188	18	etiologies	etiology	NOUN
dti-1548	188	19	and	and	CCONJ
dti-1548	188	20	ethnic	ethnic	ADJ
dti-1548	188	21	backgrounds	background	NOUN
dti-1548	188	22	(	(	PUNCT
dti-1548	188	23	15–19	15–19	NUM
dti-1548	188	24	)	)	PUNCT
dti-1548	188	25	.	.	PUNCT
dti-1548	189	1	once	once	SCONJ
dti-1548	189	2	hcc	hcc	PROPN
dti-1548	189	3	heterogeneity	heterogeneity	PROPN
dti-1548	189	4	is	be	AUX
dti-1548	189	5	accepted	accept	VERB
dti-1548	189	6	(	(	PUNCT
dti-1548	189	7	20	20	NUM
dti-1548	189	8	)	)	PUNCT
dti-1548	189	9	,	,	PUNCT
dti-1548	189	10	studies	study	NOUN
dti-1548	189	11	have	have	VERB
dti-1548	189	12	to	to	PART
dti-1548	189	13	be	be	AUX
dti-1548	189	14	conducted	conduct	VERB
dti-1548	189	15	on	on	ADP
dti-1548	189	16	homogeneous	homogeneous	ADJ
dti-1548	189	17	samples	sample	NOUN
dti-1548	189	18	to	to	PART
dti-1548	189	19	identify	identify	VERB
dti-1548	189	20	characteristic	characteristic	ADJ
dti-1548	189	21	genetic	genetic	ADJ
dti-1548	189	22	alterations	alteration	NOUN
dti-1548	189	23	,	,	PUNCT
dti-1548	189	24	if	if	SCONJ
dti-1548	189	25	personalized	personalized	ADJ
dti-1548	189	26	management	management	NOUN
dti-1548	189	27	is	be	AUX
dti-1548	189	28	the	the	DET
dti-1548	189	29	target	target	NOUN
dti-1548	189	30	.	.	PUNCT
dti-1548	190	1	fig	fig	NOUN
dti-1548	190	2	.	.	PUNCT
dti-1548	191	1	4	4	NUM
dti-1548	191	2	analysis	analysis	NOUN
dti-1548	191	3	of	of	ADP
dti-1548	191	4	canonical	canonical	ADJ
dti-1548	191	5	pathways	pathway	NOUN
dti-1548	191	6	involved	involve	VERB
dti-1548	191	7	in	in	ADP
dti-1548	191	8	hepatitis	hepatitis	PROPN
dti-1548	191	9	c	c	PROPN
dti-1548	191	10	virus	virus	NOUN
dti-1548	191	11	-	-	PUNCT
dti-1548	191	12	related	relate	VERB
dti-1548	191	13	hepatocellular	hepatocellular	ADJ
dti-1548	191	14	carcinoma	carcinoma	NOUN
dti-1548	191	15	pathogenesis	pathogenesis	NOUN
dti-1548	191	16	with	with	ADP
dti-1548	191	17	the	the	DET
dti-1548	191	18	ingenuity	ingenuity	NOUN
dti-1548	191	19	pathway	pathway	NOUN
dti-1548	191	20	analysis	analysis	NOUN
dti-1548	191	21	(	(	PUNCT
dti-1548	191	22	ipa	ipa	PROPN
dti-1548	191	23	)	)	PUNCT
dti-1548	191	24	database	database	NOUN
dti-1548	191	25	using	use	VERB
dti-1548	191	26	the	the	DET
dti-1548	191	27	present	present	ADJ
dti-1548	191	28	dataset	dataset	NOUN
dti-1548	191	29	(	(	PUNCT
dti-1548	191	30	the	the	DET
dti-1548	191	31	84	84	NUM
dti-1548	191	32	tested	test	VERB
dti-1548	191	33	genes	gene	NOUN
dti-1548	191	34	)	)	PUNCT
dti-1548	191	35	.	.	PUNCT
dti-1548	192	1	the	the	DET
dti-1548	192	2	igf	igf	PROPN
dti-1548	192	3	pathway	pathway	NOUN
dti-1548	192	4	was	be	AUX
dti-1548	192	5	found	find	VERB
dti-1548	192	6	to	to	PART
dti-1548	192	7	be	be	AUX
dti-1548	192	8	inactive	inactive	ADJ
dti-1548	192	9	.	.	PUNCT
dti-1548	193	1	on	on	ADP
dti-1548	193	2	the	the	DET
dti-1548	193	3	other	other	ADJ
dti-1548	193	4	hand	hand	NOUN
dti-1548	193	5	,	,	PUNCT
dti-1548	193	6	the	the	DET
dti-1548	193	7	nitric	nitric	ADJ
dti-1548	193	8	oxide	oxide	NOUN
dti-1548	193	9	and	and	CCONJ
dti-1548	193	10	reactive	reactive	ADJ
dti-1548	193	11	oxygen	oxygen	NOUN
dti-1548	193	12	species	specie	NOUN
dti-1548	193	13	production	production	NOUN
dti-1548	193	14	pathway	pathway	NOUN
dti-1548	193	15	were	be	AUX
dti-1548	193	16	significantly	significantly	ADV
dti-1548	193	17	activated	activate	VERB
dti-1548	193	18	.	.	PUNCT
dti-1548	194	1	description	description	NOUN
dti-1548	194	2	:	:	PUNCT
dti-1548	194	3	the	the	DET
dti-1548	194	4	white	white	ADJ
dti-1548	194	5	bars	bar	NOUN
dti-1548	194	6	mean	mean	VERB
dti-1548	194	7	that	that	SCONJ
dti-1548	194	8	half	half	DET
dti-1548	194	9	the	the	DET
dti-1548	194	10	molecules	molecule	NOUN
dti-1548	194	11	suggest	suggest	VERB
dti-1548	194	12	an	an	DET
dti-1548	194	13	activation	activation	NOUN
dti-1548	194	14	and	and	CCONJ
dti-1548	194	15	half	half	ADJ
dti-1548	194	16	suggest	suggest	VERB
dti-1548	194	17	inhibition	inhibition	NOUN
dti-1548	194	18	,	,	PUNCT
dti-1548	194	19	so	so	SCONJ
dti-1548	194	20	an	an	DET
dti-1548	194	21	overall	overall	ADJ
dti-1548	194	22	z	z	NOUN
dti-1548	194	23	-	-	PUNCT
dti-1548	194	24	score	score	NOUN
dti-1548	194	25	of	of	ADP
dti-1548	194	26	0	0	NUM
dti-1548	194	27	(	(	PUNCT
dti-1548	194	28	ingenuity	ingenuity	NOUN
dti-1548	194	29	systems	system	NOUN
dti-1548	194	30	)	)	PUNCT
dti-1548	194	31	.	.	PUNCT
dti-1548	195	1	the	the	DET
dti-1548	195	2	blue	blue	ADJ
dti-1548	195	3	bar	bar	NOUN
dti-1548	195	4	indicates	indicate	VERB
dti-1548	195	5	that	that	SCONJ
dti-1548	195	6	there	there	PRON
dti-1548	195	7	is	be	VERB
dti-1548	195	8	evidence	evidence	NOUN
dti-1548	195	9	that	that	SCONJ
dti-1548	195	10	the	the	DET
dti-1548	195	11	pathway	pathway	NOUN
dti-1548	195	12	is	be	AUX
dti-1548	195	13	inhibited	inhibit	VERB
dti-1548	195	14	and	and	CCONJ
dti-1548	195	15	a	a	DET
dti-1548	195	16	negative	negative	ADJ
dti-1548	195	17	z	z	NOUN
dti-1548	195	18	-	-	PUNCT
dti-1548	195	19	score	score	NOUN
dti-1548	195	20	.	.	PUNCT
dti-1548	196	1	the	the	DET
dti-1548	196	2	orange	orange	PROPN
dti-1548	196	3	bar	bar	PROPN
dti-1548	196	4	means	mean	VERB
dti-1548	196	5	that	that	SCONJ
dti-1548	196	6	there	there	PRON
dti-1548	196	7	is	be	VERB
dti-1548	196	8	a	a	DET
dti-1548	196	9	positive	positive	ADJ
dti-1548	196	10	z	z	NOUN
dti-1548	196	11	-	-	PUNCT
dti-1548	196	12	score	score	NOUN
dti-1548	196	13	indicating	indicate	VERB
dti-1548	196	14	that	that	SCONJ
dti-1548	196	15	there	there	PRON
dti-1548	196	16	is	be	VERB
dti-1548	196	17	evidence	evidence	NOUN
dti-1548	196	18	for	for	ADP
dti-1548	196	19	activation	activation	NOUN
dti-1548	196	20	of	of	ADP
dti-1548	196	21	this	this	DET
dti-1548	196	22	pathway	pathway	NOUN
dti-1548	196	23	.	.	PUNCT
dti-1548	197	1	the	the	DET
dti-1548	197	2	horizontal	horizontal	ADJ
dti-1548	197	3	threshold	threshold	NOUN
dti-1548	197	4	line	line	NOUN
dti-1548	197	5	indicates	indicate	VERB
dti-1548	197	6	the	the	DET
dti-1548	197	7	threshold	threshold	NOUN
dti-1548	197	8	for	for	ADP
dti-1548	197	9	the	the	DET
dti-1548	197	10	overrepresentation	overrepresentation	NOUN
dti-1548	197	11	analysis	analysis	NOUN
dti-1548	197	12	and	and	CCONJ
dti-1548	197	13	was	be	AUX
dti-1548	197	14	set	set	VERB
dti-1548	197	15	at	at	ADP
dti-1548	197	16	p	p	NOUN
dti-1548	197	17	=	=	NOUN
dti-1548	197	18	0.05	0.05	NUM
dti-1548	197	19	.	.	PUNCT
dti-1548	198	1	only	only	ADJ
dti-1548	198	2	bars	bar	NOUN
dti-1548	198	3	that	that	PRON
dti-1548	198	4	are	be	AUX
dti-1548	198	5	more	more	ADV
dti-1548	198	6	significant	significant	ADJ
dti-1548	198	7	than	than	SCONJ
dti-1548	198	8	p	p	NOUN
dti-1548	198	9	<	<	X
dti-1548	198	10	0.05	0.05	NUM
dti-1548	198	11	are	be	AUX
dti-1548	198	12	shown	show	VERB
dti-1548	198	13	.	.	PUNCT
dti-1548	199	1	the	the	DET
dti-1548	199	2	ratio	ratio	NOUN
dti-1548	199	3	line	line	NOUN
dti-1548	199	4	represents	represent	VERB
dti-1548	199	5	the	the	DET
dti-1548	199	6	ratio	ratio	NOUN
dti-1548	199	7	of	of	ADP
dti-1548	199	8	the	the	DET
dti-1548	199	9	number	number	NOUN
dti-1548	199	10	of	of	ADP
dti-1548	199	11	molecules	molecule	NOUN
dti-1548	199	12	in	in	ADP
dti-1548	199	13	the	the	DET
dti-1548	199	14	present	present	ADJ
dti-1548	199	15	dataset	dataset	NOUN
dti-1548	199	16	that	that	PRON
dti-1548	199	17	map	map	NOUN
dti-1548	199	18	into	into	ADP
dti-1548	199	19	the	the	DET
dti-1548	199	20	pathway	pathway	NOUN
dti-1548	199	21	relative	relative	ADJ
dti-1548	199	22	to	to	ADP
dti-1548	199	23	the	the	DET
dti-1548	199	24	whole	whole	ADJ
dti-1548	199	25	size	size	NOUN
dti-1548	199	26	of	of	ADP
dti-1548	199	27	the	the	DET
dti-1548	199	28	pathway	pathway	NOUN
dti-1548	199	29	(	(	PUNCT
dti-1548	199	30	ingenuity	ingenuity	NOUN
dti-1548	199	31	systems	system	NOUN
dti-1548	199	32	)	)	PUNCT
dti-1548	199	33	.	.	PUNCT
dti-1548	200	1	the	the	DET
dti-1548	200	2	pathway	pathway	NOUN
dti-1548	200	3	analysis	analysis	NOUN
dti-1548	200	4	was	be	AUX
dti-1548	200	5	generated	generate	VERB
dti-1548	200	6	through	through	ADP
dti-1548	200	7	the	the	DET
dti-1548	200	8	use	use	NOUN
dti-1548	200	9	of	of	ADP
dti-1548	200	10	ipa	ipa	PROPN
dti-1548	200	11	(	(	PUNCT
dti-1548	200	12	qiagen	qiagen	PROPN
dti-1548	200	13	inc	inc	PROPN
dti-1548	200	14	.	.	PROPN
dti-1548	200	15	,	,	PUNCT
dti-1548	200	16	https://www.qiagenbioinformatics.com/products/	https://www.qiagenbioinformatics.com/products/	PUNCT
dti-1548	200	17	ingenuity	ingenuity	NOUN
dti-1548	200	18	-	-	PUNCT
dti-1548	200	19	pathway	pathway	NOUN
dti-1548	200	20	-	-	PUNCT
dti-1548	200	21	analysis	analysis	NOUN
dti-1548	200	22	hcc	hcc	NOUN
dti-1548	200	23	is	be	AUX
dti-1548	200	24	known	know	VERB
dti-1548	200	25	to	to	PART
dti-1548	200	26	be	be	AUX
dti-1548	200	27	chemoand	chemoand	ADV
dti-1548	200	28	radioresistant	radioresistant	ADJ
dti-1548	200	29	(	(	PUNCT
dti-1548	200	30	21	21	NUM
dti-1548	200	31	)	)	PUNCT
dti-1548	200	32	;	;	PUNCT
dti-1548	200	33	therefore	therefore	ADV
dti-1548	200	34	,	,	PUNCT
dti-1548	200	35	identifying	identify	VERB
dti-1548	200	36	therapeutic	therapeutic	ADJ
dti-1548	200	37	vulnerabilities	vulnerability	NOUN
dti-1548	200	38	for	for	ADP
dti-1548	200	39	molecular	molecular	ADJ
dti-1548	200	40	targeted	target	VERB
dti-1548	200	41	drugs	drug	NOUN
dti-1548	200	42	is	be	AUX
dti-1548	200	43	in	in	ADP
dti-1548	200	44	dire	dire	ADJ
dti-1548	200	45	need	need	NOUN
dti-1548	200	46	.	.	PUNCT
dti-1548	201	1	the	the	DET
dti-1548	201	2	present	present	ADJ
dti-1548	201	3	study	study	NOUN
dti-1548	201	4	measured	measure	VERB
dti-1548	201	5	levels	level	NOUN
dti-1548	201	6	of	of	ADP
dti-1548	201	7	messenger	messenger	PROPN
dti-1548	201	8	rna	rna	PROPN
dti-1548	201	9	(	(	PUNCT
dti-1548	201	10	mrna	mrna	PROPN
dti-1548	201	11	)	)	PUNCT
dti-1548	201	12	expression	expression	NOUN
dti-1548	201	13	of	of	ADP
dti-1548	201	14	84	84	NUM
dti-1548	201	15	insulin	insulin	NOUN
dti-1548	201	16	signaling	signal	VERB
dti-1548	201	17	-	-	PUNCT
dti-1548	201	18	related	relate	VERB
dti-1548	201	19	genes	gene	NOUN
dti-1548	201	20	,	,	PUNCT
dti-1548	201	21	including	include	VERB
dti-1548	201	22	genes	gene	NOUN
dti-1548	201	23	of	of	ADP
dti-1548	201	24	the	the	DET
dti-1548	201	25	pi3k	pi3k	NOUN
dti-1548	201	26	and	and	CCONJ
dti-1548	201	27	the	the	DET
dti-1548	201	28	mapk	mapk	NOUN
dti-1548	201	29	signaling	signal	VERB
dti-1548	201	30	pathways	pathway	NOUN
dti-1548	201	31	(	(	PUNCT
dti-1548	201	32	11	11	NUM
dti-1548	201	33	)	)	PUNCT
dti-1548	201	34	.	.	PUNCT
dti-1548	202	1	also	also	ADV
dti-1548	202	2	included	include	VERB
dti-1548	202	3	are	be	AUX
dti-1548	202	4	genes	gene	NOUN
dti-1548	202	5	involved	involve	VERB
dti-1548	202	6	in	in	ADP
dti-1548	202	7	carbohydrate	carbohydrate	NOUN
dti-1548	202	8	,	,	PUNCT
dti-1548	202	9	lipid	lipid	NOUN
dti-1548	202	10	and	and	CCONJ
dti-1548	202	11	protein	protein	NOUN
dti-1548	202	12	metabolism	metabolism	NOUN
dti-1548	202	13	,	,	PUNCT
dti-1548	202	14	transcription	transcription	NOUN
dti-1548	202	15	factors	factor	NOUN
dti-1548	202	16	and	and	CCONJ
dti-1548	202	17	transcription	transcription	NOUN
dti-1548	202	18	regulators	regulator	NOUN
dti-1548	202	19	,	,	PUNCT
dti-1548	202	20	genes	gene	NOUN
dti-1548	202	21	involved	involve	VERB
dti-1548	202	22	in	in	ADP
dti-1548	202	23	cell	cell	NOUN
dti-1548	202	24	proliferation	proliferation	NOUN
dti-1548	202	25	,	,	PUNCT
dti-1548	202	26	growth	growth	NOUN
dti-1548	202	27	,	,	PUNCT
dti-1548	202	28	and	and	CCONJ
dti-1548	202	29	differentiation	differentiation	NOUN
dti-1548	202	30	(	(	PUNCT
dti-1548	202	31	12	12	NUM
dti-1548	202	32	)	)	PUNCT
dti-1548	202	33	.	.	PUNCT
dti-1548	203	1	of	of	ADP
dti-1548	203	2	the	the	DET
dti-1548	203	3	84	84	NUM
dti-1548	203	4	-	-	PUNCT
dti-1548	203	5	cancer	cancer	NOUN
dti-1548	203	6	pathway	pathway	NOUN
dti-1548	203	7	-	-	PUNCT
dti-1548	203	8	focused	focus	VERB
dti-1548	203	9	genes	gene	NOUN
dti-1548	203	10	in	in	ADP
dti-1548	203	11	this	this	DET
dti-1548	203	12	array	array	NOUN
dti-1548	203	13	,	,	PUNCT
dti-1548	203	14	upregulation	upregulation	NOUN
dti-1548	203	15	was	be	AUX
dti-1548	203	16	observed	observe	VERB
dti-1548	203	17	in	in	ADP
dti-1548	203	18	14	14	NUM
dti-1548	203	19	genes	gene	NOUN
dti-1548	203	20	,	,	PUNCT
dti-1548	203	21	while	while	SCONJ
dti-1548	203	22	37	37	NUM
dti-1548	203	23	genes	gene	NOUN
dti-1548	203	24	appeared	appear	VERB
dti-1548	203	25	to	to	PART
dti-1548	203	26	be	be	AUX
dti-1548	203	27	downregulated	downregulate	VERB
dti-1548	203	28	in	in	ADP
dti-1548	203	29	the	the	DET
dti-1548	203	30	tumor	tumor	NOUN
dti-1548	203	31	samples	sample	NOUN
dti-1548	203	32	,	,	PUNCT
dti-1548	203	33	for	for	ADP
dti-1548	203	34	a	a	DET
dti-1548	203	35	total	total	NOUN
dti-1548	203	36	of	of	ADP
dti-1548	203	37	51	51	NUM
dti-1548	203	38	differentially	differentially	ADV
dti-1548	203	39	regulated	regulate	VERB
dti-1548	203	40	genes	gene	NOUN
dti-1548	203	41	.	.	PUNCT
dti-1548	204	1	these	these	DET
dti-1548	204	2	upregulated	upregulate	VERB
dti-1548	204	3	genes	gene	NOUN
dti-1548	204	4	may	may	AUX
dti-1548	204	5	be	be	AUX
dti-1548	204	6	therapeutic	therapeutic	ADJ
dti-1548	204	7	targets	target	NOUN
dti-1548	204	8	for	for	ADP
dti-1548	204	9	future	future	ADJ
dti-1548	204	10	trials	trial	NOUN
dti-1548	204	11	,	,	PUNCT
dti-1548	204	12	especially	especially	ADV
dti-1548	204	13	those	those	PRON
dti-1548	204	14	for	for	ADP
dti-1548	204	15	which	which	PRON
dti-1548	204	16	molecularly	molecularly	ADV
dti-1548	204	17	targeted	target	VERB
dti-1548	204	18	agents	agent	NOUN
dti-1548	204	19	are	be	AUX
dti-1548	204	20	available	available	ADJ
dti-1548	204	21	.	.	PUNCT
dti-1548	205	1	among	among	ADP
dti-1548	205	2	the	the	DET
dti-1548	205	3	significantly	significantly	ADV
dti-1548	205	4	upregulated	upregulated	ADJ
dti-1548	205	5	genes	gene	NOUN
dti-1548	205	6	was	be	AUX
dti-1548	205	7	c	c	NOUN
dti-1548	205	8	-	-	PUNCT
dti-1548	205	9	fos	fos	NOUN
dti-1548	205	10	,	,	PUNCT
dti-1548	205	11	a	a	DET
dti-1548	205	12	proto	proto	NOUN
dti-1548	205	13	-	-	PUNCT
dti-1548	205	14	oncogene	oncogene	NOUN
dti-1548	205	15	which	which	PRON
dti-1548	205	16	is	be	AUX
dti-1548	205	17	a	a	DET
dti-1548	205	18	major	major	ADJ
dti-1548	205	19	nuclear	nuclear	ADJ
dti-1548	205	20	target	target	NOUN
dti-1548	205	21	for	for	ADP
dti-1548	205	22	signal	signal	ADJ
dti-1548	205	23	transduction	transduction	NOUN
dti-1548	205	24	pathways	pathway	NOUN
dti-1548	205	25	,	,	PUNCT
dti-1548	205	26	including	include	VERB
dti-1548	205	27	mapk	mapk	NOUN
dti-1548	205	28	pathway	pathway	NOUN
dti-1548	205	29	,	,	PUNCT
dti-1548	205	30	and	and	CCONJ
dti-1548	205	31	is	be	AUX
dti-1548	205	32	involved	involve	VERB
dti-1548	205	33	in	in	ADP
dti-1548	205	34	the	the	DET
dti-1548	205	35	regulation	regulation	NOUN
dti-1548	205	36	of	of	ADP
dti-1548	205	37	cell	cell	NOUN
dti-1548	205	38	growth	growth	NOUN
dti-1548	205	39	,	,	PUNCT
dti-1548	205	40	differentiation	differentiation	NOUN
dti-1548	205	41	,	,	PUNCT
dti-1548	205	42	and	and	CCONJ
dti-1548	205	43	transformation	transformation	NOUN
dti-1548	205	44	(	(	PUNCT
dti-1548	205	45	22,23	22,23	NOUN
dti-1548	205	46	)	)	PUNCT
dti-1548	205	47	.	.	PUNCT
dti-1548	206	1	a	a	DET
dti-1548	206	2	novel	novel	ADJ
dti-1548	206	3	selective	selective	ADJ
dti-1548	206	4	c	c	NOUN
dti-1548	206	5	-	-	PUNCT
dti-1548	206	6	fos	fos	VERB
dti-1548	206	7	/	/	SYM
dti-1548	206	8	ap-1	ap-1	NOUN
dti-1548	206	9	inhibitor	inhibitor	NOUN
dti-1548	206	10	t‐5224	t‐5224	NOUN
dti-1548	206	11	was	be	AUX
dti-1548	206	12	found	find	VERB
dti-1548	206	13	to	to	PART
dti-1548	206	14	inhibit	inhibit	VERB
dti-1548	206	15	the	the	DET
dti-1548	206	16	invasion	invasion	NOUN
dti-1548	206	17	and	and	CCONJ
dti-1548	206	18	migration	migration	NOUN
dti-1548	206	19	of	of	ADP
dti-1548	206	20	head	head	NOUN
dti-1548	206	21	and	and	CCONJ
dti-1548	206	22	neck	neck	VERB
dti-1548	206	23	squamous	squamous	ADJ
dti-1548	206	24	cell	cell	NOUN
dti-1548	206	25	carcinoma	carcinoma	NOUN
dti-1548	206	26	cells	cell	NOUN
dti-1548	206	27	in	in	ADP
dti-1548	206	28	vitro	vitro	NOUN
dti-1548	206	29	and	and	CCONJ
dti-1548	206	30	prevented	prevent	VERB
dti-1548	206	31	lymph	lymph	NOUN
dti-1548	206	32	node	node	NOUN
dti-1548	206	33	metastasis	metastasis	NOUN
dti-1548	206	34	in	in	ADP
dti-1548	206	35	head	head	NOUN
dti-1548	206	36	and	and	CCONJ
dti-1548	206	37	neck	neck	NOUN
dti-1548	206	38	cancer	cancer	NOUN
dti-1548	206	39	in	in	ADP
dti-1548	206	40	an	an	DET
dti-1548	206	41	animal	animal	NOUN
dti-1548	206	42	model	model	NOUN
dti-1548	206	43	(	(	PUNCT
dti-1548	206	44	24	24	NUM
dti-1548	206	45	)	)	PUNCT
dti-1548	206	46	.	.	PUNCT
dti-1548	207	1	most	most	ADJ
dti-1548	207	2	of	of	ADP
dti-1548	207	3	the	the	DET
dti-1548	207	4	significantly	significantly	ADV
dti-1548	207	5	upregulated	upregulated	ADJ
dti-1548	207	6	genes	gene	NOUN
dti-1548	207	7	found	find	VERB
dti-1548	207	8	in	in	ADP
dti-1548	207	9	the	the	DET
dti-1548	207	10	present	present	ADJ
dti-1548	207	11	work	work	NOUN
dti-1548	207	12	were	be	AUX
dti-1548	207	13	also	also	ADV
dti-1548	207	14	found	find	VERB
dti-1548	207	15	in	in	ADP
dti-1548	207	16	common	common	ADJ
dti-1548	207	17	with	with	ADP
dti-1548	207	18	prior	prior	ADJ
dti-1548	207	19	hcc	hcc	PROPN
dti-1548	207	20	possible	possible	ADJ
dti-1548	207	21	therapeutic	therapeutic	ADJ
dti-1548	207	22	targets	target	NOUN
dti-1548	207	23	in	in	ADP
dti-1548	207	24	igf1r	igf1r	ADJ
dti-1548	207	25	pathway	pathway	NOUN
dti-1548	207	26	in	in	ADP
dti-1548	207	27	egyptian	egyptian	PROPN
dti-1548	207	28	hcv	hcv	X
dti-1548	207	29	related	relate	VERB
dti-1548	207	30	hcc8	hcc8	NOUN
dti-1548	207	31	©	©	PROPN
dti-1548	207	32	2020	2020	NUM
dti-1548	207	33	the	the	DET
dti-1548	207	34	authors	author	NOUN
dti-1548	207	35	.	.	PUNCT
dti-1548	208	1	published	publish	VERB
dti-1548	208	2	by	by	ADP
dti-1548	208	3	aboutscience	aboutscience	NOUN
dti-1548	208	4	and	and	CCONJ
dti-1548	208	5	clinical	clinical	ADJ
dti-1548	208	6	trials	trial	NOUN
dti-1548	208	7	to	to	PART
dti-1548	208	8	be	be	AUX
dti-1548	208	9	conducted	conduct	VERB
dti-1548	208	10	for	for	ADP
dti-1548	208	11	agents	agent	NOUN
dti-1548	208	12	targeting	target	VERB
dti-1548	208	13	those	those	DET
dti-1548	208	14	upregulated	upregulated	ADJ
dti-1548	208	15	genes	gene	NOUN
dti-1548	208	16	to	to	PART
dti-1548	208	17	test	test	VERB
dti-1548	208	18	their	their	PRON
dti-1548	208	19	efficacy	efficacy	NOUN
dti-1548	208	20	and	and	CCONJ
dti-1548	208	21	their	their	PRON
dti-1548	208	22	potential	potential	ADJ
dti-1548	208	23	use	use	NOUN
dti-1548	208	24	in	in	ADP
dti-1548	208	25	hcv	hcv	NOUN
dti-1548	208	26	-	-	PUNCT
dti-1548	208	27	related	relate	VERB
dti-1548	208	28	hcc	hcc	PROPN
dti-1548	208	29	treatment	treatment	NOUN
dti-1548	208	30	.	.	PUNCT
dti-1548	209	1	the	the	DET
dti-1548	209	2	13	13	NUM
dti-1548	209	3	significantly	significantly	ADV
dti-1548	209	4	downregulated	downregulate	VERB
dti-1548	209	5	genes	gene	NOUN
dti-1548	209	6	included	include	VERB
dti-1548	209	7	genes	gene	NOUN
dti-1548	209	8	involved	involve	VERB
dti-1548	209	9	in	in	ADP
dti-1548	209	10	carbohydrate	carbohydrate	NOUN
dti-1548	209	11	,	,	PUNCT
dti-1548	209	12	protein	protein	NOUN
dti-1548	209	13	,	,	PUNCT
dti-1548	209	14	and	and	CCONJ
dti-1548	209	15	lipid	lipid	ADJ
dti-1548	209	16	metabolism	metabolism	NOUN
dti-1548	209	17	,	,	PUNCT
dti-1548	209	18	pi3k	pi3k	NOUN
dti-1548	209	19	signaling	signal	VERB
dti-1548	209	20	target	target	NOUN
dti-1548	209	21	genes	gene	NOUN
dti-1548	209	22	,	,	PUNCT
dti-1548	209	23	mapk	mapk	NOUN
dti-1548	209	24	signaling	signal	VERB
dti-1548	209	25	target	target	NOUN
dti-1548	209	26	genes	gene	NOUN
dti-1548	209	27	,	,	PUNCT
dti-1548	209	28	insulin	insulin	NOUN
dti-1548	209	29	receptor	receptor	NOUN
dti-1548	209	30	-	-	PUNCT
dti-1548	209	31	associated	associate	VERB
dti-1548	209	32	proteins	protein	NOUN
dti-1548	209	33	,	,	PUNCT
dti-1548	209	34	genes	gene	NOUN
dti-1548	209	35	involved	involve	VERB
dti-1548	209	36	in	in	ADP
dti-1548	209	37	cell	cell	NOUN
dti-1548	209	38	cycle	cycle	NOUN
dti-1548	209	39	,	,	PUNCT
dti-1548	209	40	cell	cell	NOUN
dti-1548	209	41	proliferation	proliferation	NOUN
dti-1548	209	42	,	,	PUNCT
dti-1548	209	43	growth	growth	NOUN
dti-1548	209	44	factors	factor	NOUN
dti-1548	209	45	and	and	CCONJ
dti-1548	209	46	receptors	receptor	NOUN
dti-1548	209	47	,	,	PUNCT
dti-1548	209	48	insulin	insulin	NOUN
dti-1548	209	49	gene	gene	NOUN
dti-1548	209	50	and	and	CCONJ
dti-1548	209	51	insulin	insulin	NOUN
dti-1548	209	52	receptor	receptor	NOUN
dti-1548	209	53	-	-	PUNCT
dti-1548	209	54	associated	associate	VERB
dti-1548	209	55	proteins	protein	NOUN
dti-1548	209	56	,	,	PUNCT
dti-1548	209	57	primary	primary	ADJ
dti-1548	209	58	insulin	insulin	NOUN
dti-1548	209	59	signaling	signal	VERB
dti-1548	209	60	target	target	NOUN
dti-1548	209	61	genes	gene	NOUN
dti-1548	209	62	,	,	PUNCT
dti-1548	209	63	transcription	transcription	NOUN
dti-1548	209	64	factors	factor	NOUN
dti-1548	209	65	,	,	PUNCT
dti-1548	209	66	and	and	CCONJ
dti-1548	209	67	transcription	transcription	NOUN
dti-1548	209	68	regulators	regulator	NOUN
dti-1548	209	69	(	(	PUNCT
dti-1548	209	70	12	12	NUM
dti-1548	209	71	)	)	PUNCT
dti-1548	209	72	.	.	PUNCT
dti-1548	210	1	two	two	NUM
dti-1548	210	2	of	of	ADP
dti-1548	210	3	those	those	PRON
dti-1548	210	4	were	be	AUX
dti-1548	210	5	tumor	tumor	NOUN
dti-1548	210	6	suppressor	suppressor	NOUN
dti-1548	210	7	genes	gene	NOUN
dti-1548	210	8	.	.	PUNCT
dti-1548	211	1	cebpa	cebpa	NOUN
dti-1548	211	2	has	have	AUX
dti-1548	211	3	been	be	AUX
dti-1548	211	4	described	describe	VERB
dti-1548	211	5	as	as	ADP
dti-1548	211	6	a	a	DET
dti-1548	211	7	tumor	tumor	NOUN
dti-1548	211	8	suppressor	suppressor	NOUN
dti-1548	211	9	,	,	PUNCT
dti-1548	211	10	leading	lead	VERB
dti-1548	211	11	to	to	ADP
dti-1548	211	12	mitotic	mitotic	ADJ
dti-1548	211	13	arrest	arrest	NOUN
dti-1548	211	14	through	through	ADP
dti-1548	211	15	activation	activation	NOUN
dti-1548	211	16	of	of	ADP
dti-1548	211	17	p21	p21	NOUN
dti-1548	211	18	and	and	CCONJ
dti-1548	211	19	repression	repression	NOUN
dti-1548	211	20	of	of	ADP
dti-1548	211	21	e2fs	e2fs	NOUN
dti-1548	211	22	and	and	CCONJ
dti-1548	211	23	cyclin	cyclin	NOUN
dti-1548	211	24	-	-	PUNCT
dti-1548	211	25	dependent	dependent	ADJ
dti-1548	211	26	kinases	kinase	NOUN
dti-1548	211	27	(	(	PUNCT
dti-1548	211	28	50	50	NUM
dti-1548	211	29	)	)	PUNCT
dti-1548	211	30	.	.	PUNCT
dti-1548	212	1	its	its	PRON
dti-1548	212	2	expression	expression	NOUN
dti-1548	212	3	is	be	AUX
dti-1548	212	4	downregulated	downregulate	VERB
dti-1548	212	5	in	in	ADP
dti-1548	212	6	a	a	DET
dti-1548	212	7	number	number	NOUN
dti-1548	212	8	of	of	ADP
dti-1548	212	9	cancers	cancer	NOUN
dti-1548	212	10	including	include	VERB
dti-1548	212	11	lung	lung	NOUN
dti-1548	212	12	(	(	PUNCT
dti-1548	212	13	51	51	NUM
dti-1548	212	14	)	)	PUNCT
dti-1548	212	15	,	,	PUNCT
dti-1548	212	16	breast	breast	NOUN
dti-1548	212	17	cancers	cancer	NOUN
dti-1548	212	18	(	(	PUNCT
dti-1548	212	19	52	52	NUM
dti-1548	212	20	)	)	PUNCT
dti-1548	212	21	,	,	PUNCT
dti-1548	212	22	head	head	NOUN
dti-1548	212	23	and	and	CCONJ
dti-1548	212	24	neck	neck	VERB
dti-1548	212	25	squamous	squamous	ADJ
dti-1548	212	26	cell	cell	NOUN
dti-1548	212	27	carcinoma	carcinoma	NOUN
dti-1548	212	28	(	(	PUNCT
dti-1548	212	29	53	53	NUM
dti-1548	212	30	)	)	PUNCT
dti-1548	212	31	,	,	PUNCT
dti-1548	212	32	and	and	CCONJ
dti-1548	212	33	hcc	hcc	PROPN
dti-1548	212	34	.	.	PUNCT
dti-1548	213	1	its	its	PRON
dti-1548	213	2	downregulation	downregulation	NOUN
dti-1548	213	3	was	be	AUX
dti-1548	213	4	associated	associate	VERB
dti-1548	213	5	with	with	ADP
dti-1548	213	6	advanced	advanced	ADJ
dti-1548	213	7	hcc	hcc	PROPN
dti-1548	213	8	stages	stage	NOUN
dti-1548	213	9	and	and	CCONJ
dti-1548	213	10	poor	poor	ADJ
dti-1548	213	11	survival	survival	NOUN
dti-1548	213	12	(	(	PUNCT
dti-1548	213	13	54,55	54,55	NOUN
dti-1548	213	14	)	)	PUNCT
dti-1548	213	15	.	.	PUNCT
dti-1548	214	1	recently	recently	ADV
dti-1548	214	2	,	,	PUNCT
dti-1548	214	3	a	a	DET
dti-1548	214	4	modified	modify	VERB
dti-1548	214	5	small	small	ADJ
dti-1548	214	6	activating	activate	VERB
dti-1548	214	7	rna	rna	PROPN
dti-1548	214	8	(	(	PUNCT
dti-1548	214	9	sarna	sarna	PROPN
dti-1548	214	10	)	)	PUNCT
dti-1548	214	11	retained	retain	VERB
dti-1548	214	12	activation	activation	NOUN
dti-1548	214	13	of	of	ADP
dti-1548	214	14	cebpa	cebpa	NOUN
dti-1548	214	15	mrna	mrna	PROPN
dti-1548	214	16	and	and	CCONJ
dti-1548	214	17	downstream	downstream	ADJ
dti-1548	214	18	targets	target	NOUN
dti-1548	214	19	and	and	CCONJ
dti-1548	214	20	inhibited	inhibit	VERB
dti-1548	214	21	growth	growth	NOUN
dti-1548	214	22	of	of	ADP
dti-1548	214	23	liver	liver	NOUN
dti-1548	214	24	cancer	cancer	NOUN
dti-1548	214	25	cell	cell	NOUN
dti-1548	214	26	lines	line	NOUN
dti-1548	214	27	in	in	ADP
dti-1548	214	28	vitro	vitro	X
dti-1548	214	29	(	(	PUNCT
dti-1548	214	30	56	56	NUM
dti-1548	214	31	)	)	PUNCT
dti-1548	214	32	.	.	PUNCT
dti-1548	215	1	this	this	DET
dti-1548	215	2	novel	novel	ADJ
dti-1548	215	3	drug	drug	NOUN
dti-1548	215	4	has	have	AUX
dti-1548	215	5	been	be	AUX
dti-1548	215	6	encapsulated	encapsulate	VERB
dti-1548	215	7	in	in	ADP
dti-1548	215	8	a	a	DET
dti-1548	215	9	liposomal	liposomal	ADJ
dti-1548	215	10	formulation	formulation	NOUN
dti-1548	215	11	for	for	ADP
dti-1548	215	12	liver	liver	NOUN
dti-1548	215	13	delivery	delivery	NOUN
dti-1548	215	14	in	in	ADP
dti-1548	215	15	humans	human	NOUN
dti-1548	215	16	and	and	CCONJ
dti-1548	215	17	is	be	AUX
dti-1548	215	18	currently	currently	ADV
dti-1548	215	19	in	in	ADP
dti-1548	215	20	a	a	DET
dti-1548	215	21	phase	phase	NOUN
dti-1548	215	22	i	i	PRON
dti-1548	215	23	clinical	clinical	ADJ
dti-1548	215	24	trial	trial	NOUN
dti-1548	215	25	for	for	ADP
dti-1548	215	26	patients	patient	NOUN
dti-1548	215	27	with	with	ADP
dti-1548	215	28	liver	liver	NOUN
dti-1548	215	29	cancer	cancer	NOUN
dti-1548	215	30	and	and	CCONJ
dti-1548	215	31	represents	represent	VERB
dti-1548	215	32	the	the	DET
dti-1548	215	33	first	first	ADJ
dti-1548	215	34	human	human	ADJ
dti-1548	215	35	study	study	NOUN
dti-1548	215	36	of	of	ADP
dti-1548	215	37	a	a	DET
dti-1548	215	38	sarna	sarna	NOUN
dti-1548	215	39	therapeutic	therapeutic	ADJ
dti-1548	215	40	(	(	PUNCT
dti-1548	215	41	57	57	NUM
dti-1548	215	42	)	)	PUNCT
dti-1548	215	43	.	.	PUNCT
dti-1548	216	1	frs3	frs3	PROPN
dti-1548	216	2	was	be	AUX
dti-1548	216	3	significantly	significantly	ADV
dti-1548	216	4	downregulated	downregulate	VERB
dti-1548	216	5	in	in	ADP
dti-1548	216	6	our	our	PRON
dti-1548	216	7	patient	patient	NOUN
dti-1548	216	8	cohort	cohort	NOUN
dti-1548	216	9	.	.	PUNCT
dti-1548	217	1	this	this	PRON
dti-1548	217	2	is	be	AUX
dti-1548	217	3	the	the	DET
dti-1548	217	4	first	first	ADJ
dti-1548	217	5	report	report	NOUN
dti-1548	217	6	of	of	ADP
dti-1548	217	7	its	its	PRON
dti-1548	217	8	significant	significant	ADJ
dti-1548	217	9	downregulation	downregulation	NOUN
dti-1548	217	10	in	in	ADP
dti-1548	217	11	hccs	hccs	NOUN
dti-1548	217	12	.	.	PUNCT
dti-1548	218	1	similar	similar	ADJ
dti-1548	218	2	to	to	ADP
dti-1548	218	3	our	our	PRON
dti-1548	218	4	findings	finding	NOUN
dti-1548	218	5	,	,	PUNCT
dti-1548	218	6	frs3	frs3	NOUN
dti-1548	218	7	expression	expression	NOUN
dti-1548	218	8	level	level	NOUN
dti-1548	218	9	has	have	AUX
dti-1548	218	10	been	be	AUX
dti-1548	218	11	found	find	VERB
dti-1548	218	12	to	to	PART
dti-1548	218	13	be	be	AUX
dti-1548	218	14	downregulated	downregulate	VERB
dti-1548	218	15	in	in	ADP
dti-1548	218	16	brain	brain	NOUN
dti-1548	218	17	and	and	CCONJ
dti-1548	218	18	lung	lung	NOUN
dti-1548	218	19	cancer	cancer	NOUN
dti-1548	218	20	cell	cell	NOUN
dti-1548	218	21	lines	line	NOUN
dti-1548	218	22	.	.	PUNCT
dti-1548	219	1	it	it	PRON
dti-1548	219	2	constitutively	constitutively	ADV
dti-1548	219	3	binds	bind	VERB
dti-1548	219	4	to	to	PART
dti-1548	219	5	egfr	egfr	NOUN
dti-1548	219	6	regardless	regardless	ADV
dti-1548	219	7	of	of	ADP
dti-1548	219	8	egf	egf	PROPN
dti-1548	219	9	stimulation	stimulation	NOUN
dti-1548	219	10	and	and	CCONJ
dti-1548	219	11	inhibits	inhibit	VERB
dti-1548	219	12	egf	egf	NOUN
dti-1548	219	13	-	-	PUNCT
dti-1548	219	14	induced	induce	VERB
dti-1548	219	15	cell	cell	NOUN
dti-1548	219	16	transformation	transformation	NOUN
dti-1548	219	17	and	and	CCONJ
dti-1548	219	18	proliferation	proliferation	NOUN
dti-1548	219	19	(	(	PUNCT
dti-1548	219	20	58	58	NUM
dti-1548	219	21	)	)	PUNCT
dti-1548	219	22	.	.	PUNCT
dti-1548	220	1	it	it	PRON
dti-1548	220	2	serves	serve	VERB
dti-1548	220	3	as	as	ADP
dti-1548	220	4	a	a	DET
dti-1548	220	5	tumor	tumor	NOUN
dti-1548	220	6	suppressor	suppressor	NOUN
dti-1548	220	7	in	in	ADP
dti-1548	220	8	non	non	ADJ
dti-1548	220	9	-	-	ADJ
dti-1548	220	10	small	small	ADJ
dti-1548	220	11	cell	cell	NOUN
dti-1548	220	12	lung	lung	NOUN
dti-1548	220	13	cancer	cancer	NOUN
dti-1548	220	14	(	(	PUNCT
dti-1548	220	15	nsclc	nsclc	NOUN
dti-1548	220	16	)	)	PUNCT
dti-1548	220	17	(	(	PUNCT
dti-1548	220	18	59	59	NUM
dti-1548	220	19	)	)	PUNCT
dti-1548	220	20	.	.	PUNCT
dti-1548	221	1	in	in	ADP
dti-1548	221	2	our	our	PRON
dti-1548	221	3	work	work	NOUN
dti-1548	221	4	,	,	PUNCT
dti-1548	221	5	excision	excision	NOUN
dti-1548	221	6	repair	repair	NOUN
dti-1548	221	7	cross	cross	ADJ
dti-1548	221	8	-	-	ADJ
dti-1548	221	9	complementing	complement	VERB
dti-1548	221	10	rodent	rodent	ADJ
dti-1548	221	11	repair	repair	NOUN
dti-1548	221	12	deficiency	deficiency	NOUN
dti-1548	221	13	,	,	PUNCT
dti-1548	221	14	complementation	complementation	NOUN
dti-1548	221	15	group	group	NOUN
dti-1548	221	16	1	1	NUM
dti-1548	221	17	(	(	PUNCT
dti-1548	221	18	ercc1	ercc1	NOUN
dti-1548	221	19	)	)	PUNCT
dti-1548	221	20	was	be	AUX
dti-1548	221	21	significantly	significantly	ADV
dti-1548	221	22	downregulated	downregulate	VERB
dti-1548	221	23	.	.	PUNCT
dti-1548	222	1	it	it	PRON
dti-1548	222	2	was	be	AUX
dti-1548	222	3	also	also	ADV
dti-1548	222	4	found	find	VERB
dti-1548	222	5	to	to	PART
dti-1548	222	6	be	be	AUX
dti-1548	222	7	downregulated	downregulate	VERB
dti-1548	222	8	in	in	ADP
dti-1548	222	9	chinese	chinese	PROPN
dti-1548	222	10	(	(	PUNCT
dti-1548	222	11	47	47	NUM
dti-1548	222	12	)	)	PUNCT
dti-1548	222	13	and	and	CCONJ
dti-1548	222	14	turkish	turkish	ADJ
dti-1548	222	15	(	(	PUNCT
dti-1548	222	16	60	60	NUM
dti-1548	222	17	)	)	PUNCT
dti-1548	222	18	hcc	hcc	NOUN
dti-1548	222	19	cohorts	cohort	NOUN
dti-1548	222	20	as	as	ADV
dti-1548	222	21	well	well	ADV
dti-1548	222	22	.	.	PUNCT
dti-1548	223	1	loss	loss	NOUN
dti-1548	223	2	of	of	ADP
dti-1548	223	3	ercc1	ercc1	NOUN
dti-1548	223	4	expression	expression	NOUN
dti-1548	223	5	in	in	ADP
dti-1548	223	6	hepatocytes	hepatocyte	NOUN
dti-1548	223	7	may	may	AUX
dti-1548	223	8	be	be	AUX
dti-1548	223	9	one	one	NUM
dti-1548	223	10	of	of	ADP
dti-1548	223	11	the	the	DET
dti-1548	223	12	leading	lead	VERB
dti-1548	223	13	factors	factor	NOUN
dti-1548	223	14	for	for	ADP
dti-1548	223	15	genetic	genetic	ADJ
dti-1548	223	16	instability	instability	NOUN
dti-1548	223	17	,	,	PUNCT
dti-1548	223	18	and	and	CCONJ
dti-1548	223	19	thus	thus	ADV
dti-1548	223	20	of	of	ADP
dti-1548	223	21	tumorigenesis	tumorigenesis	NOUN
dti-1548	223	22	(	(	PUNCT
dti-1548	223	23	61	61	NUM
dti-1548	223	24	)	)	PUNCT
dti-1548	223	25	.	.	PUNCT
dti-1548	224	1	impaired	impair	VERB
dti-1548	224	2	nucleotide	nucleotide	NOUN
dti-1548	224	3	excision	excision	NOUN
dti-1548	224	4	repair	repair	NOUN
dti-1548	224	5	pathway	pathway	NOUN
dti-1548	224	6	,	,	PUNCT
dti-1548	224	7	in	in	ADP
dti-1548	224	8	which	which	PRON
dti-1548	224	9	ercc1	ercc1	NOUN
dti-1548	224	10	plays	play	VERB
dti-1548	224	11	a	a	DET
dti-1548	224	12	major	major	ADJ
dti-1548	224	13	role	role	NOUN
dti-1548	224	14	,	,	PUNCT
dti-1548	224	15	leads	lead	VERB
dti-1548	224	16	to	to	ADP
dti-1548	224	17	reduced	reduce	VERB
dti-1548	224	18	dna	dna	PROPN
dti-1548	224	19	repair	repair	NOUN
dti-1548	224	20	capability	capability	NOUN
dti-1548	224	21	and	and	CCONJ
dti-1548	224	22	increases	increase	VERB
dti-1548	224	23	dna	dna	PROPN
dti-1548	224	24	adduct	adduct	NOUN
dti-1548	224	25	levels	level	NOUN
dti-1548	224	26	and	and	CCONJ
dti-1548	224	27	genomic	genomic	NOUN
dti-1548	224	28	instability	instability	NOUN
dti-1548	224	29	that	that	SCONJ
dti-1548	224	30	in	in	ADP
dti-1548	224	31	turn	turn	NOUN
dti-1548	224	32	could	could	AUX
dti-1548	224	33	lead	lead	VERB
dti-1548	224	34	to	to	ADP
dti-1548	224	35	a	a	DET
dti-1548	224	36	more	more	ADV
dti-1548	224	37	malignant	malignant	ADJ
dti-1548	224	38	phenotype	phenotype	NOUN
dti-1548	224	39	(	(	PUNCT
dti-1548	224	40	62	62	NUM
dti-1548	224	41	)	)	PUNCT
dti-1548	224	42	.	.	PUNCT
dti-1548	225	1	this	this	PRON
dti-1548	225	2	is	be	AUX
dti-1548	225	3	not	not	PART
dti-1548	225	4	limited	limit	VERB
dti-1548	225	5	to	to	ADP
dti-1548	225	6	hccs	hccs	NOUN
dti-1548	225	7	,	,	PUNCT
dti-1548	225	8	but	but	CCONJ
dti-1548	225	9	also	also	ADV
dti-1548	225	10	is	be	AUX
dti-1548	225	11	a	a	DET
dti-1548	225	12	finding	finding	NOUN
dti-1548	225	13	in	in	ADP
dti-1548	225	14	other	other	ADJ
dti-1548	225	15	types	type	NOUN
dti-1548	225	16	of	of	ADP
dti-1548	225	17	cancer	cancer	NOUN
dti-1548	225	18	including	include	VERB
dti-1548	225	19	head	head	NOUN
dti-1548	225	20	and	and	CCONJ
dti-1548	225	21	neck	neck	VERB
dti-1548	225	22	squamous	squamous	ADJ
dti-1548	225	23	cell	cell	NOUN
dti-1548	225	24	carcinoma	carcinoma	NOUN
dti-1548	225	25	(	(	PUNCT
dti-1548	225	26	63	63	NUM
dti-1548	225	27	)	)	PUNCT
dti-1548	225	28	.	.	PUNCT
dti-1548	226	1	gene	gene	NOUN
dti-1548	226	2	expression	expression	NOUN
dti-1548	226	3	patterns	pattern	NOUN
dti-1548	226	4	can	can	AUX
dti-1548	226	5	be	be	AUX
dti-1548	226	6	used	use	VERB
dti-1548	226	7	to	to	PART
dti-1548	226	8	define	define	VERB
dti-1548	226	9	the	the	DET
dti-1548	226	10	suitable	suitable	ADJ
dti-1548	226	11	chemotherapeutic	chemotherapeutic	ADJ
dti-1548	226	12	agent	agent	NOUN
dti-1548	226	13	employed	employ	VERB
dti-1548	226	14	in	in	ADP
dti-1548	226	15	any	any	DET
dti-1548	226	16	given	give	VERB
dti-1548	226	17	case	case	NOUN
dti-1548	226	18	.	.	PUNCT
dti-1548	227	1	ercc1	ercc1	NOUN
dti-1548	227	2	overexpression	overexpression	NOUN
dti-1548	227	3	could	could	AUX
dti-1548	227	4	be	be	AUX
dti-1548	227	5	associated	associate	VERB
dti-1548	227	6	with	with	ADP
dti-1548	227	7	resistance	resistance	NOUN
dti-1548	227	8	to	to	ADP
dti-1548	227	9	cisplatin	cisplatin	NOUN
dti-1548	227	10	-	-	PUNCT
dti-1548	227	11	based	base	VERB
dti-1548	227	12	therapy	therapy	NOUN
dti-1548	227	13	in	in	ADP
dti-1548	227	14	hcc	hcc	PROPN
dti-1548	227	15	,	,	PUNCT
dti-1548	227	16	similar	similar	ADJ
dti-1548	227	17	to	to	ADP
dti-1548	227	18	what	what	PRON
dti-1548	227	19	is	be	AUX
dti-1548	227	20	observed	observe	VERB
dti-1548	227	21	in	in	ADP
dti-1548	227	22	nsclc	nsclc	NOUN
dti-1548	227	23	(	(	PUNCT
dti-1548	227	24	64,65	64,65	NOUN
dti-1548	227	25	)	)	PUNCT
dti-1548	227	26	.	.	PUNCT
dti-1548	228	1	vegfa	vegfa	PROPN
dti-1548	228	2	was	be	AUX
dti-1548	228	3	found	find	VERB
dti-1548	228	4	to	to	PART
dti-1548	228	5	be	be	AUX
dti-1548	228	6	downregulated	downregulate	VERB
dti-1548	228	7	in	in	ADP
dti-1548	228	8	the	the	DET
dti-1548	228	9	present	present	ADJ
dti-1548	228	10	study	study	NOUN
dti-1548	228	11	in	in	ADP
dti-1548	228	12	71.9	71.9	NUM
dti-1548	228	13	%	%	NOUN
dti-1548	228	14	of	of	ADP
dti-1548	228	15	cases	case	NOUN
dti-1548	228	16	.	.	PUNCT
dti-1548	229	1	several	several	ADJ
dti-1548	229	2	retrospective	retrospective	ADJ
dti-1548	229	3	studies	study	NOUN
dti-1548	229	4	suggested	suggest	VERB
dti-1548	229	5	that	that	SCONJ
dti-1548	229	6	tumors	tumor	NOUN
dti-1548	229	7	with	with	ADP
dti-1548	229	8	a	a	DET
dti-1548	229	9	vegfa	vegfa	PROPN
dti-1548	229	10	amplification	amplification	NOUN
dti-1548	229	11	respond	respond	VERB
dti-1548	229	12	better	well	ADV
dti-1548	229	13	to	to	PART
dti-1548	229	14	sorafenib	sorafenib	VERB
dti-1548	229	15	,	,	PUNCT
dti-1548	229	16	the	the	DET
dti-1548	229	17	only	only	ADJ
dti-1548	229	18	approved	approve	VERB
dti-1548	229	19	first	first	ADJ
dti-1548	229	20	-	-	PUNCT
dti-1548	229	21	line	line	NOUN
dti-1548	229	22	treatment	treatment	NOUN
dti-1548	229	23	of	of	ADP
dti-1548	229	24	advanced	advanced	ADJ
dti-1548	229	25	hcc	hcc	PROPN
dti-1548	229	26	(	(	PUNCT
dti-1548	229	27	66	66	NUM
dti-1548	229	28	)	)	PUNCT
dti-1548	229	29	,	,	PUNCT
dti-1548	229	30	suggesting	suggest	VERB
dti-1548	229	31	that	that	SCONJ
dti-1548	229	32	further	further	ADJ
dti-1548	229	33	studies	study	NOUN
dti-1548	229	34	of	of	ADP
dti-1548	229	35	currently	currently	ADV
dti-1548	229	36	used	use	VERB
dti-1548	229	37	molecularly	molecularly	ADV
dti-1548	229	38	targeted	target	VERB
dti-1548	229	39	therapies	therapy	NOUN
dti-1548	229	40	in	in	ADP
dti-1548	229	41	egyptian	egyptian	ADJ
dti-1548	229	42	hcv	hcv	PROPN
dti-1548	229	43	-	-	PUNCT
dti-1548	229	44	related	relate	VERB
dti-1548	229	45	hcc	hcc	PROPN
dti-1548	229	46	patients	patient	NOUN
dti-1548	229	47	are	be	AUX
dti-1548	229	48	needed	need	VERB
dti-1548	229	49	,	,	PUNCT
dti-1548	229	50	and	and	CCONJ
dti-1548	229	51	search	search	VERB
dti-1548	229	52	for	for	ADP
dti-1548	229	53	molecular	molecular	ADJ
dti-1548	229	54	biomarkers	biomarker	NOUN
dti-1548	229	55	of	of	ADP
dti-1548	229	56	response	response	NOUN
dti-1548	229	57	to	to	ADP
dti-1548	229	58	therapy	therapy	NOUN
dti-1548	229	59	with	with	ADP
dti-1548	229	60	prospective	prospective	ADJ
dti-1548	229	61	molecular	molecular	ADJ
dti-1548	229	62	studies	study	NOUN
dti-1548	229	63	;	;	PUNCT
dti-1548	229	64	akt2	akt2	ADJ
dti-1548	229	65	,	,	PUNCT
dti-1548	229	66	c	c	NOUN
dti-1548	229	67	-	-	PUNCT
dti-1548	229	68	fos	fos	NOUN
dti-1548	229	69	,	,	PUNCT
dti-1548	229	70	pik3r1	pik3r1	ADJ
dti-1548	229	71	,	,	PUNCT
dti-1548	229	72	prkcι	prkcι	PROPN
dti-1548	229	73	,	,	PUNCT
dti-1548	229	74	shc1	shc1	PROPN
dti-1548	229	75	were	be	AUX
dti-1548	229	76	all	all	PRON
dti-1548	229	77	found	find	VERB
dti-1548	229	78	to	to	PART
dti-1548	229	79	be	be	AUX
dti-1548	229	80	similarly	similarly	ADV
dti-1548	229	81	significantly	significantly	ADV
dti-1548	229	82	upregulated	upregulate	VERB
dti-1548	229	83	(	(	PUNCT
dti-1548	229	84	25–30	25–30	NUM
dti-1548	229	85	)	)	PUNCT
dti-1548	229	86	.	.	PUNCT
dti-1548	230	1	aebp1	aebp1	PROPN
dti-1548	230	2	is	be	AUX
dti-1548	230	3	an	an	DET
dti-1548	230	4	exception	exception	NOUN
dti-1548	230	5	;	;	PUNCT
dti-1548	230	6	to	to	ADP
dti-1548	230	7	the	the	DET
dti-1548	230	8	best	good	ADJ
dti-1548	230	9	of	of	ADP
dti-1548	230	10	our	our	PRON
dti-1548	230	11	knowledge	knowledge	NOUN
dti-1548	230	12	,	,	PUNCT
dti-1548	230	13	this	this	PRON
dti-1548	230	14	is	be	AUX
dti-1548	230	15	the	the	DET
dti-1548	230	16	first	first	ADJ
dti-1548	230	17	report	report	NOUN
dti-1548	230	18	to	to	PART
dti-1548	230	19	find	find	VERB
dti-1548	230	20	this	this	DET
dti-1548	230	21	gene	gene	NOUN
dti-1548	230	22	to	to	PART
dti-1548	230	23	be	be	AUX
dti-1548	230	24	significantly	significantly	ADV
dti-1548	230	25	and	and	CCONJ
dti-1548	230	26	consistently	consistently	ADV
dti-1548	230	27	(	(	PUNCT
dti-1548	230	28	>	>	SYM
dti-1548	230	29	90	90	NUM
dti-1548	230	30	%	%	NOUN
dti-1548	230	31	of	of	ADP
dti-1548	230	32	hccs	hccs	NOUN
dti-1548	230	33	)	)	PUNCT
dti-1548	230	34	upregulated	upregulate	VERB
dti-1548	230	35	in	in	ADP
dti-1548	230	36	hcc	hcc	PROPN
dti-1548	230	37	.	.	PUNCT
dti-1548	231	1	it	it	PRON
dti-1548	231	2	is	be	AUX
dti-1548	231	3	a	a	DET
dti-1548	231	4	transcriptional	transcriptional	ADJ
dti-1548	231	5	repressor	repressor	NOUN
dti-1548	231	6	that	that	PRON
dti-1548	231	7	has	have	AUX
dti-1548	231	8	been	be	AUX
dti-1548	231	9	studied	study	VERB
dti-1548	231	10	in	in	ADP
dti-1548	231	11	great	great	ADJ
dti-1548	231	12	detail	detail	NOUN
dti-1548	231	13	for	for	ADP
dti-1548	231	14	its	its	PRON
dti-1548	231	15	role	role	NOUN
dti-1548	231	16	in	in	ADP
dti-1548	231	17	regulating	regulate	VERB
dti-1548	231	18	adipogenesis	adipogenesis	NOUN
dti-1548	231	19	(	(	PUNCT
dti-1548	231	20	31	31	NUM
dti-1548	231	21	)	)	PUNCT
dti-1548	231	22	.	.	PUNCT
dti-1548	232	1	it	it	PRON
dti-1548	232	2	has	have	AUX
dti-1548	232	3	also	also	ADV
dti-1548	232	4	been	be	AUX
dti-1548	232	5	found	find	VERB
dti-1548	232	6	to	to	PART
dti-1548	232	7	be	be	AUX
dti-1548	232	8	a	a	DET
dti-1548	232	9	proinflammatory	proinflammatory	ADJ
dti-1548	232	10	mediator	mediator	NOUN
dti-1548	232	11	(	(	PUNCT
dti-1548	232	12	32	32	NUM
dti-1548	232	13	)	)	PUNCT
dti-1548	232	14	.	.	PUNCT
dti-1548	233	1	finally	finally	ADV
dti-1548	233	2	,	,	PUNCT
dti-1548	233	3	it	it	PRON
dti-1548	233	4	has	have	AUX
dti-1548	233	5	been	be	AUX
dti-1548	233	6	shown	show	VERB
dti-1548	233	7	that	that	SCONJ
dti-1548	233	8	aebp1	aebp1	PROPN
dti-1548	233	9	induces	induce	VERB
dti-1548	233	10	massive	massive	ADJ
dti-1548	233	11	obesity	obesity	NOUN
dti-1548	233	12	in	in	ADP
dti-1548	233	13	mice	mouse	NOUN
dti-1548	233	14	with	with	ADP
dti-1548	233	15	targeted	target	VERB
dti-1548	233	16	overexpression	overexpression	NOUN
dti-1548	233	17	of	of	ADP
dti-1548	233	18	aebp1	aebp1	NOUN
dti-1548	233	19	in	in	ADP
dti-1548	233	20	adipose	adipose	PRON
dti-1548	233	21	tissue	tissue	NOUN
dti-1548	233	22	(	(	PUNCT
dti-1548	233	23	33	33	NUM
dti-1548	233	24	)	)	PUNCT
dti-1548	233	25	.	.	PUNCT
dti-1548	234	1	although	although	SCONJ
dti-1548	234	2	its	its	PRON
dti-1548	234	3	exact	exact	ADJ
dti-1548	234	4	role	role	NOUN
dti-1548	234	5	in	in	ADP
dti-1548	234	6	tumorigenesis	tumorigenesis	NOUN
dti-1548	234	7	is	be	AUX
dti-1548	234	8	not	not	PART
dti-1548	234	9	clear	clear	ADJ
dti-1548	234	10	(	(	PUNCT
dti-1548	234	11	34	34	NUM
dti-1548	234	12	)	)	PUNCT
dti-1548	234	13	,	,	PUNCT
dti-1548	234	14	aebp1	aebp1	PROPN
dti-1548	234	15	was	be	AUX
dti-1548	234	16	found	find	VERB
dti-1548	234	17	to	to	PART
dti-1548	234	18	be	be	AUX
dti-1548	234	19	upregulated	upregulate	VERB
dti-1548	234	20	in	in	ADP
dti-1548	234	21	many	many	ADJ
dti-1548	234	22	different	different	ADJ
dti-1548	234	23	cancers	cancer	NOUN
dti-1548	234	24	such	such	ADJ
dti-1548	234	25	as	as	ADP
dti-1548	234	26	cervical	cervical	ADJ
dti-1548	234	27	cancer	cancer	NOUN
dti-1548	234	28	(	(	PUNCT
dti-1548	234	29	35,36	35,36	NUM
dti-1548	234	30	)	)	PUNCT
dti-1548	234	31	,	,	PUNCT
dti-1548	234	32	primary	primary	ADJ
dti-1548	234	33	glioblastoma	glioblastoma	NOUN
dti-1548	234	34	multiforme	multiforme	NOUN
dti-1548	234	35	(	(	PUNCT
dti-1548	234	36	37	37	NUM
dti-1548	234	37	)	)	PUNCT
dti-1548	234	38	,	,	PUNCT
dti-1548	234	39	and	and	CCONJ
dti-1548	234	40	human	human	ADJ
dti-1548	234	41	breast	breast	NOUN
dti-1548	234	42	cancer	cancer	NOUN
dti-1548	234	43	cell	cell	NOUN
dti-1548	234	44	lines	line	NOUN
dti-1548	234	45	(	(	PUNCT
dti-1548	234	46	38	38	NUM
dti-1548	234	47	)	)	PUNCT
dti-1548	234	48	.	.	PUNCT
dti-1548	235	1	ladha	ladha	PROPN
dti-1548	235	2	et	et	PROPN
dti-1548	235	3	al	al	PROPN
dti-1548	235	4	found	find	VERB
dti-1548	235	5	that	that	SCONJ
dti-1548	235	6	silencing	silence	VERB
dti-1548	235	7	aebp1	aebp1	NOUN
dti-1548	235	8	expression	expression	NOUN
dti-1548	235	9	and	and	CCONJ
dti-1548	235	10	loss	loss	NOUN
dti-1548	235	11	of	of	ADP
dti-1548	235	12	its	its	PRON
dti-1548	235	13	function	function	NOUN
dti-1548	235	14	lead	lead	NOUN
dti-1548	235	15	to	to	ADP
dti-1548	235	16	apoptosis	apoptosis	NOUN
dti-1548	235	17	in	in	ADP
dti-1548	235	18	glioma	glioma	NOUN
dti-1548	235	19	cell	cell	NOUN
dti-1548	235	20	lines	line	NOUN
dti-1548	235	21	,	,	PUNCT
dti-1548	235	22	meaning	mean	VERB
dti-1548	235	23	that	that	SCONJ
dti-1548	235	24	aebp1	aebp1	PROPN
dti-1548	235	25	has	have	VERB
dti-1548	235	26	an	an	DET
dti-1548	235	27	antiapoptotic	antiapoptotic	ADJ
dti-1548	235	28	function	function	NOUN
dti-1548	235	29	and	and	CCONJ
dti-1548	235	30	is	be	AUX
dti-1548	235	31	an	an	DET
dti-1548	235	32	important	important	ADJ
dti-1548	235	33	survival	survival	NOUN
dti-1548	235	34	factor	factor	NOUN
dti-1548	235	35	for	for	ADP
dti-1548	235	36	tumor	tumor	NOUN
dti-1548	235	37	cells	cell	NOUN
dti-1548	235	38	(	(	PUNCT
dti-1548	235	39	34	34	NUM
dti-1548	235	40	)	)	PUNCT
dti-1548	235	41	.	.	PUNCT
dti-1548	236	1	two	two	NUM
dti-1548	236	2	studies	study	NOUN
dti-1548	236	3	found	find	VERB
dti-1548	236	4	that	that	SCONJ
dti-1548	236	5	directly	directly	ADV
dti-1548	236	6	targeting	target	VERB
dti-1548	236	7	akt2	akt2	NOUN
dti-1548	236	8	by	by	ADP
dti-1548	236	9	mir302b	mir302b	PROPN
dti-1548	236	10	in	in	ADP
dti-1548	236	11	human	human	ADJ
dti-1548	236	12	hcc	hcc	PROPN
dti-1548	236	13	cells	cell	NOUN
dti-1548	236	14	suppresses	suppress	VERB
dti-1548	236	15	cell	cell	NOUN
dti-1548	236	16	proliferation	proliferation	NOUN
dti-1548	236	17	,	,	PUNCT
dti-1548	236	18	invasion	invasion	NOUN
dti-1548	236	19	,	,	PUNCT
dti-1548	236	20	and	and	CCONJ
dti-1548	236	21	metastasis	metastasis	NOUN
dti-1548	236	22	in	in	ADP
dti-1548	236	23	vitro	vitro	X
dti-1548	236	24	and	and	CCONJ
dti-1548	236	25	also	also	ADV
dti-1548	236	26	inhibited	inhibit	VERB
dti-1548	236	27	hcc	hcc	PROPN
dti-1548	236	28	tumor	tumor	NOUN
dti-1548	236	29	growth	growth	NOUN
dti-1548	236	30	in	in	ADP
dti-1548	236	31	vivo	vivo	NOUN
dti-1548	236	32	(	(	PUNCT
dti-1548	236	33	25,39	25,39	NOUN
dti-1548	236	34	)	)	PUNCT
dti-1548	236	35	.	.	PUNCT
dti-1548	237	1	a	a	DET
dti-1548	237	2	recent	recent	ADJ
dti-1548	237	3	preclinical	preclinical	NOUN
dti-1548	237	4	in	in	ADP
dti-1548	237	5	vitro	vitro	X
dti-1548	237	6	and	and	CCONJ
dti-1548	237	7	in	in	ADP
dti-1548	237	8	vivo	vivo	ADJ
dti-1548	237	9	trial	trial	NOUN
dti-1548	237	10	using	use	VERB
dti-1548	237	11	a	a	DET
dti-1548	237	12	highly	highly	ADV
dti-1548	237	13	selective	selective	ADJ
dti-1548	237	14	allosteric	allosteric	ADJ
dti-1548	237	15	pan	pan	NOUN
dti-1548	237	16	-	-	ADJ
dti-1548	237	17	akt	akt	NOUN
dti-1548	237	18	inhibitor	inhibitor	NOUN
dti-1548	237	19	in	in	ADP
dti-1548	237	20	combination	combination	NOUN
dti-1548	237	21	with	with	ADP
dti-1548	237	22	sorafenib	sorafenib	NOUN
dti-1548	237	23	found	find	VERB
dti-1548	237	24	that	that	SCONJ
dti-1548	237	25	this	this	DET
dti-1548	237	26	combination	combination	NOUN
dti-1548	237	27	yielded	yield	VERB
dti-1548	237	28	better	well	ADJ
dti-1548	237	29	outcomes	outcome	NOUN
dti-1548	237	30	and	and	CCONJ
dti-1548	237	31	with	with	ADP
dti-1548	237	32	minimal	minimal	ADJ
dti-1548	237	33	toxicity	toxicity	NOUN
dti-1548	237	34	than	than	ADP
dti-1548	237	35	sorafenib	sorafenib	NOUN
dti-1548	237	36	alone	alone	ADV
dti-1548	237	37	.	.	PUNCT
dti-1548	238	1	the	the	DET
dti-1548	238	2	combination	combination	NOUN
dti-1548	238	3	significantly	significantly	ADV
dti-1548	238	4	reduced	reduce	VERB
dti-1548	238	5	tumor	tumor	NOUN
dti-1548	238	6	growth	growth	NOUN
dti-1548	238	7	,	,	PUNCT
dti-1548	238	8	proliferation	proliferation	NOUN
dti-1548	238	9	,	,	PUNCT
dti-1548	238	10	and	and	CCONJ
dti-1548	238	11	angiogenesis	angiogenesis	NOUN
dti-1548	238	12	and	and	CCONJ
dti-1548	238	13	increased	increase	VERB
dti-1548	238	14	apoptosis	apoptosis	NOUN
dti-1548	238	15	(	(	PUNCT
dti-1548	238	16	40	40	NUM
dti-1548	238	17	)	)	PUNCT
dti-1548	238	18	.	.	PUNCT
dti-1548	239	1	the	the	DET
dti-1548	239	2	pkcι	pkcι	NOUN
dti-1548	239	3	blocking	block	VERB
dti-1548	239	4	agent	agent	NOUN
dti-1548	239	5	aurothiomalate	aurothiomalate	ADV
dti-1548	239	6	(	(	PUNCT
dti-1548	239	7	atm	atm	NOUN
dti-1548	239	8	)	)	PUNCT
dti-1548	239	9	was	be	AUX
dti-1548	239	10	found	find	VERB
dti-1548	239	11	to	to	PART
dti-1548	239	12	negatively	negatively	ADV
dti-1548	239	13	regulate	regulate	VERB
dti-1548	239	14	emt	emt	NOUN
dti-1548	239	15	and	and	CCONJ
dti-1548	239	16	invasion	invasion	NOUN
dti-1548	239	17	of	of	ADP
dti-1548	239	18	hcc	hcc	PROPN
dti-1548	239	19	in	in	ADP
dti-1548	239	20	immortalized	immortalized	ADJ
dti-1548	239	21	murine	murine	ADJ
dti-1548	239	22	hepatocytes	hepatocyte	NOUN
dti-1548	239	23	and	and	CCONJ
dti-1548	239	24	was	be	AUX
dti-1548	239	25	found	find	VERB
dti-1548	239	26	to	to	PART
dti-1548	239	27	inhibit	inhibit	VERB
dti-1548	239	28	proliferation	proliferation	NOUN
dti-1548	239	29	and	and	CCONJ
dti-1548	239	30	induce	induce	VERB
dti-1548	239	31	apoptosis	apoptosis	NOUN
dti-1548	239	32	in	in	ADP
dti-1548	239	33	hepg2	hepg2	NOUN
dti-1548	239	34	cells	cell	NOUN
dti-1548	239	35	(	(	PUNCT
dti-1548	239	36	41	41	NUM
dti-1548	239	37	)	)	PUNCT
dti-1548	239	38	.	.	PUNCT
dti-1548	240	1	also	also	ADV
dti-1548	240	2	,	,	PUNCT
dti-1548	240	3	a	a	DET
dti-1548	240	4	recent	recent	ADJ
dti-1548	240	5	patent	patent	NOUN
dti-1548	240	6	has	have	AUX
dti-1548	240	7	been	be	AUX
dti-1548	240	8	published	publish	VERB
dti-1548	240	9	on	on	ADP
dti-1548	240	10	a	a	DET
dti-1548	240	11	novel	novel	ADJ
dti-1548	240	12	drug	drug	NOUN
dti-1548	240	13	targeting	target	VERB
dti-1548	240	14	pkcι	pkcι	NOUN
dti-1548	240	15	.	.	PUNCT
dti-1548	241	1	it	it	PRON
dti-1548	241	2	has	have	AUX
dti-1548	241	3	been	be	AUX
dti-1548	241	4	found	find	VERB
dti-1548	241	5	to	to	PART
dti-1548	241	6	be	be	AUX
dti-1548	241	7	effective	effective	ADJ
dti-1548	241	8	at	at	ADP
dti-1548	241	9	treating	treat	VERB
dti-1548	241	10	colon	colon	NOUN
dti-1548	241	11	cancer	cancer	NOUN
dti-1548	241	12	cells	cell	NOUN
dti-1548	241	13	having	have	VERB
dti-1548	241	14	high	high	ADJ
dti-1548	241	15	level	level	NOUN
dti-1548	241	16	of	of	ADP
dti-1548	241	17	expression	expression	NOUN
dti-1548	241	18	of	of	ADP
dti-1548	241	19	at	at	ADV
dti-1548	241	20	least	least	ADV
dti-1548	241	21	one	one	NUM
dti-1548	241	22	apkc	apkc	NOUN
dti-1548	241	23	(	(	PUNCT
dti-1548	241	24	42	42	NUM
dti-1548	241	25	)	)	PUNCT
dti-1548	241	26	.	.	PUNCT
dti-1548	242	1	these	these	PRON
dti-1548	242	2	can	can	AUX
dti-1548	242	3	potentially	potentially	ADV
dti-1548	242	4	be	be	AUX
dti-1548	242	5	tested	test	VERB
dti-1548	242	6	in	in	ADP
dti-1548	242	7	preclinical	preclinical	ADJ
dti-1548	242	8	trials	trial	NOUN
dti-1548	242	9	as	as	ADP
dti-1548	242	10	a	a	DET
dti-1548	242	11	method	method	NOUN
dti-1548	242	12	for	for	ADP
dti-1548	242	13	treating	treat	VERB
dti-1548	242	14	hccs	hccs	NOUN
dti-1548	242	15	overexpressing	overexpresse	VERB
dti-1548	242	16	atypical	atypical	ADJ
dti-1548	242	17	pkcs	pkcs	NOUN
dti-1548	242	18	.	.	PUNCT
dti-1548	243	1	similarly	similarly	ADV
dti-1548	243	2	,	,	PUNCT
dti-1548	243	3	pkcι	pkcι	PROPN
dti-1548	243	4	was	be	AUX
dti-1548	243	5	upregulated	upregulate	VERB
dti-1548	243	6	in	in	ADP
dti-1548	243	7	hcc	hcc	PROPN
dti-1548	243	8	in	in	ADP
dti-1548	243	9	several	several	ADJ
dti-1548	243	10	studies	study	NOUN
dti-1548	243	11	involving	involve	VERB
dti-1548	243	12	different	different	ADJ
dti-1548	243	13	ethnic	ethnic	ADJ
dti-1548	243	14	groups	group	NOUN
dti-1548	243	15	;	;	PUNCT
dti-1548	243	16	two	two	NUM
dti-1548	243	17	chinese	chinese	ADJ
dti-1548	243	18	studies	study	NOUN
dti-1548	243	19	(	(	PUNCT
dti-1548	243	20	wang	wang	PROPN
dti-1548	243	21	et	et	PROPN
dti-1548	243	22	al	al	PROPN
dti-1548	243	23	(	(	PUNCT
dti-1548	243	24	43	43	NUM
dti-1548	243	25	)	)	PUNCT
dti-1548	243	26	,	,	PUNCT
dti-1548	243	27	du	du	PROPN
dti-1548	243	28	et	et	PROPN
dti-1548	243	29	al	al	PROPN
dti-1548	243	30	(	(	PUNCT
dti-1548	243	31	44	44	NUM
dti-1548	243	32	)	)	PUNCT
dti-1548	243	33	)	)	PUNCT
dti-1548	243	34	and	and	CCONJ
dti-1548	243	35	an	an	DET
dti-1548	243	36	american	american	ADJ
dti-1548	243	37	and	and	CCONJ
dti-1548	243	38	spanish	spanish	ADJ
dti-1548	243	39	study	study	NOUN
dti-1548	243	40	(	(	PUNCT
dti-1548	243	41	chiang	chiang	PROPN
dti-1548	243	42	et	et	PROPN
dti-1548	243	43	al	al	PROPN
dti-1548	243	44	(	(	PUNCT
dti-1548	243	45	45	45	NUM
dti-1548	243	46	)	)	PUNCT
dti-1548	243	47	)	)	PUNCT
dti-1548	243	48	.	.	PUNCT
dti-1548	244	1	boyault	boyault	PROPN
dti-1548	244	2	et	et	PROPN
dti-1548	244	3	al	al	PROPN
dti-1548	244	4	in	in	ADP
dti-1548	244	5	a	a	DET
dti-1548	244	6	french	french	ADJ
dti-1548	244	7	study	study	NOUN
dti-1548	244	8	attempted	attempt	VERB
dti-1548	244	9	to	to	PART
dti-1548	244	10	classify	classify	VERB
dti-1548	244	11	hcc	hcc	PROPN
dti-1548	244	12	by	by	ADP
dti-1548	244	13	unsupervised	unsupervised	ADJ
dti-1548	244	14	hierarchical	hierarchical	ADJ
dti-1548	244	15	clustering	clustering	NOUN
dti-1548	244	16	according	accord	VERB
dti-1548	244	17	to	to	ADP
dti-1548	244	18	the	the	DET
dti-1548	244	19	tumors	tumor	NOUN
dti-1548	244	20	’	'	PUNCT
dti-1548	244	21	gene	gene	NOUN
dti-1548	244	22	expression	expression	NOUN
dti-1548	244	23	profiles	profile	NOUN
dti-1548	244	24	by	by	ADP
dti-1548	244	25	microarray	microarray	NOUN
dti-1548	244	26	;	;	PUNCT
dti-1548	244	27	all	all	DET
dti-1548	244	28	three	three	NUM
dti-1548	244	29	generated	generate	VERB
dti-1548	244	30	subgroups	subgroup	NOUN
dti-1548	244	31	had	have	VERB
dti-1548	244	32	upregulated	upregulate	VERB
dti-1548	244	33	pkcι	pkcι	NOUN
dti-1548	244	34	(	(	PUNCT
dti-1548	244	35	the	the	DET
dti-1548	244	36	hbv	hbv	NOUN
dti-1548	244	37	and	and	CCONJ
dti-1548	244	38	non	non	ADJ
dti-1548	244	39	-	-	ADJ
dti-1548	244	40	hbv	hbv	NOUN
dti-1548	244	41	-	-	PUNCT
dti-1548	244	42	related	relate	VERB
dti-1548	244	43	hccs	hccs	NOUN
dti-1548	244	44	)	)	PUNCT
dti-1548	244	45	(	(	PUNCT
dti-1548	244	46	46	46	NUM
dti-1548	244	47	)	)	PUNCT
dti-1548	244	48	.	.	PUNCT
dti-1548	245	1	in	in	ADP
dti-1548	245	2	line	line	NOUN
dti-1548	245	3	with	with	ADP
dti-1548	245	4	our	our	PRON
dti-1548	245	5	findings	finding	NOUN
dti-1548	245	6	,	,	PUNCT
dti-1548	245	7	pik3r1	pik3r1	PROPN
dti-1548	245	8	was	be	AUX
dti-1548	245	9	found	find	VERB
dti-1548	245	10	to	to	PART
dti-1548	245	11	be	be	AUX
dti-1548	245	12	upregulated	upregulate	VERB
dti-1548	245	13	in	in	ADP
dti-1548	245	14	hcv	hcv	NOUN
dti-1548	245	15	-	-	PUNCT
dti-1548	245	16	related	relate	VERB
dti-1548	245	17	hcc	hcc	PROPN
dti-1548	245	18	subgroups	subgroup	NOUN
dti-1548	245	19	(	(	PUNCT
dti-1548	245	20	45	45	NUM
dti-1548	245	21	)	)	PUNCT
dti-1548	245	22	and	and	CCONJ
dti-1548	245	23	in	in	ADP
dti-1548	245	24	hcc	hcc	PROPN
dti-1548	245	25	patients	patient	NOUN
dti-1548	245	26	of	of	ADP
dti-1548	245	27	chinese	chinese	ADJ
dti-1548	245	28	ethnicity	ethnicity	NOUN
dti-1548	245	29	as	as	ADV
dti-1548	245	30	well	well	ADV
dti-1548	245	31	(	(	PUNCT
dti-1548	245	32	47	47	NUM
dti-1548	245	33	)	)	PUNCT
dti-1548	245	34	.	.	PUNCT
dti-1548	246	1	in	in	ADP
dti-1548	246	2	a	a	DET
dti-1548	246	3	recent	recent	ADJ
dti-1548	246	4	study	study	NOUN
dti-1548	246	5	by	by	ADP
dti-1548	246	6	he	he	PRON
dti-1548	246	7	et	et	PROPN
dti-1548	246	8	al	al	PROPN
dti-1548	246	9	,	,	PUNCT
dti-1548	246	10	pik3r1	pik3r1	ADJ
dti-1548	246	11	transfection	transfection	NOUN
dti-1548	246	12	by	by	ADP
dti-1548	246	13	small	small	ADJ
dti-1548	246	14	interfering	interfere	VERB
dti-1548	246	15	rna	rna	NOUN
dti-1548	246	16	significantly	significantly	ADV
dti-1548	246	17	inhibited	inhibit	VERB
dti-1548	246	18	hcc	hcc	PROPN
dti-1548	246	19	cell	cell	NOUN
dti-1548	246	20	migration	migration	NOUN
dti-1548	246	21	and	and	CCONJ
dti-1548	246	22	invasion	invasion	NOUN
dti-1548	246	23	(	(	PUNCT
dti-1548	246	24	48	48	NUM
dti-1548	246	25	)	)	PUNCT
dti-1548	246	26	.	.	PUNCT
dti-1548	247	1	there	there	PRON
dti-1548	247	2	are	be	VERB
dti-1548	247	3	several	several	ADJ
dti-1548	247	4	pi3k	pi3k	NOUN
dti-1548	247	5	inhibitors	inhibitor	NOUN
dti-1548	247	6	including	include	VERB
dti-1548	247	7	both	both	CCONJ
dti-1548	247	8	pan	pan	NOUN
dti-1548	247	9	-	-	ADJ
dti-1548	247	10	pi3k	pi3k	NOUN
dti-1548	247	11	and	and	CCONJ
dti-1548	247	12	isoform	isoform	NOUN
dti-1548	247	13	-	-	PUNCT
dti-1548	247	14	specific	specific	ADJ
dti-1548	247	15	pi3k	pi3k	NOUN
dti-1548	247	16	inhibitors	inhibitor	NOUN
dti-1548	247	17	that	that	PRON
dti-1548	247	18	are	be	AUX
dti-1548	247	19	still	still	ADV
dti-1548	247	20	in	in	ADP
dti-1548	247	21	early	early	ADJ
dti-1548	247	22	phase	phase	NOUN
dti-1548	247	23	clinical	clinical	ADJ
dti-1548	247	24	trials	trial	NOUN
dti-1548	247	25	(	(	PUNCT
dti-1548	247	26	49	49	NUM
dti-1548	247	27	)	)	PUNCT
dti-1548	247	28	.	.	PUNCT
dti-1548	248	1	the	the	DET
dti-1548	248	2	strongest	strong	ADJ
dti-1548	248	3	associations	association	NOUN
dti-1548	248	4	between	between	ADP
dti-1548	248	5	upregulated	upregulated	ADJ
dti-1548	248	6	genes	gene	NOUN
dti-1548	248	7	in	in	ADP
dti-1548	248	8	the	the	DET
dti-1548	248	9	present	present	ADJ
dti-1548	248	10	study	study	NOUN
dti-1548	248	11	were	be	AUX
dti-1548	248	12	between	between	ADP
dti-1548	248	13	aebp1	aebp1	PROPN
dti-1548	248	14	,	,	PUNCT
dti-1548	248	15	shc1	shc1	PROPN
dti-1548	248	16	,	,	PUNCT
dti-1548	248	17	akt2	akt2	PROPN
dti-1548	248	18	,	,	PUNCT
dti-1548	248	19	and	and	CCONJ
dti-1548	248	20	prkci	prkci	ADJ
dti-1548	248	21	.	.	PUNCT
dti-1548	249	1	possibly	possibly	ADV
dti-1548	249	2	,	,	PUNCT
dti-1548	249	3	these	these	DET
dti-1548	249	4	associations	association	NOUN
dti-1548	249	5	can	can	AUX
dti-1548	249	6	serve	serve	VERB
dti-1548	249	7	as	as	ADP
dti-1548	249	8	a	a	DET
dti-1548	249	9	guide	guide	NOUN
dti-1548	249	10	to	to	PART
dti-1548	249	11	molecularly	molecularly	ADV
dti-1548	249	12	targeted	target	VERB
dti-1548	249	13	therapy	therapy	NOUN
dti-1548	249	14	combinations	combination	NOUN
dti-1548	249	15	to	to	PART
dti-1548	249	16	cotarget	cotarget	VERB
dti-1548	249	17	the	the	DET
dti-1548	249	18	genes	gene	NOUN
dti-1548	249	19	that	that	PRON
dti-1548	249	20	were	be	AUX
dti-1548	249	21	most	most	ADV
dti-1548	249	22	frequently	frequently	ADV
dti-1548	249	23	coregulated	coregulate	VERB
dti-1548	249	24	to	to	PART
dti-1548	249	25	maximize	maximize	VERB
dti-1548	249	26	the	the	DET
dti-1548	249	27	benefits	benefit	NOUN
dti-1548	249	28	in	in	ADP
dti-1548	249	29	hcc	hcc	PROPN
dti-1548	249	30	therapy	therapy	NOUN
dti-1548	249	31	.	.	PUNCT
dti-1548	250	1	these	these	DET
dti-1548	250	2	potential	potential	ADJ
dti-1548	250	3	therapeutic	therapeutic	ADJ
dti-1548	250	4	targets	target	NOUN
dti-1548	250	5	and	and	CCONJ
dti-1548	250	6	combinations	combination	NOUN
dti-1548	250	7	open	open	VERB
dti-1548	250	8	several	several	ADJ
dti-1548	250	9	pipelines	pipeline	NOUN
dti-1548	250	10	for	for	ADP
dti-1548	250	11	future	future	ADJ
dti-1548	250	12	preclinical	preclinical	ADJ
dti-1548	250	13	mabrouk	mabrouk	NOUN
dti-1548	250	14	et	et	NOUN
dti-1548	250	15	al	al	PROPN
dti-1548	250	16	9	9	NUM
dti-1548	250	17	©	©	PROPN
dti-1548	250	18	2020	2020	NUM
dti-1548	250	19	the	the	DET
dti-1548	250	20	authors	author	NOUN
dti-1548	250	21	.	.	PUNCT
dti-1548	251	1	published	publish	VERB
dti-1548	251	2	by	by	ADP
dti-1548	251	3	aboutscience	aboutscience	NOUN
dti-1548	251	4	validation	validation	NOUN
dti-1548	251	5	of	of	ADP
dti-1548	251	6	the	the	DET
dti-1548	251	7	role	role	NOUN
dti-1548	251	8	of	of	ADP
dti-1548	251	9	vegfa	vegfa	PROPN
dti-1548	251	10	expression	expression	NOUN
dti-1548	251	11	level	level	NOUN
dti-1548	251	12	to	to	PART
dti-1548	251	13	predict	predict	VERB
dti-1548	251	14	response	response	NOUN
dti-1548	251	15	to	to	ADP
dti-1548	251	16	therapy	therapy	NOUN
dti-1548	251	17	.	.	PUNCT
dti-1548	252	1	one	one	NUM
dti-1548	252	2	of	of	ADP
dti-1548	252	3	the	the	DET
dti-1548	252	4	points	point	NOUN
dti-1548	252	5	of	of	ADP
dti-1548	252	6	strength	strength	NOUN
dti-1548	252	7	in	in	ADP
dti-1548	252	8	our	our	PRON
dti-1548	252	9	study	study	NOUN
dti-1548	252	10	is	be	AUX
dti-1548	252	11	that	that	SCONJ
dti-1548	252	12	we	we	PRON
dti-1548	252	13	included	include	VERB
dti-1548	252	14	hcc	hcc	PROPN
dti-1548	252	15	samples	sample	NOUN
dti-1548	252	16	resulting	result	VERB
dti-1548	252	17	from	from	ADP
dti-1548	252	18	a	a	DET
dti-1548	252	19	single	single	ADJ
dti-1548	252	20	etiologic	etiologic	ADJ
dti-1548	252	21	agent	agent	NOUN
dti-1548	252	22	only	only	ADV
dti-1548	252	23	(	(	PUNCT
dti-1548	252	24	hcv	hcv	NOUN
dti-1548	252	25	genotype	genotype	NOUN
dti-1548	252	26	4	4	NUM
dti-1548	252	27	-	-	PUNCT
dti-1548	252	28	related	relate	VERB
dti-1548	252	29	hcc	hcc	NOUN
dti-1548	252	30	)	)	PUNCT
dti-1548	252	31	.	.	PUNCT
dti-1548	253	1	also	also	ADV
dti-1548	253	2	,	,	PUNCT
dti-1548	253	3	the	the	DET
dti-1548	253	4	present	present	ADJ
dti-1548	253	5	study	study	NOUN
dti-1548	253	6	unified	unify	VERB
dti-1548	253	7	the	the	DET
dti-1548	253	8	controls	control	NOUN
dti-1548	253	9	used	use	VERB
dti-1548	253	10	in	in	ADP
dti-1548	253	11	the	the	DET
dti-1548	253	12	analysis	analysis	NOUN
dti-1548	253	13	as	as	SCONJ
dti-1548	253	14	we	we	PRON
dti-1548	253	15	used	use	VERB
dti-1548	253	16	healthy	healthy	ADJ
dti-1548	253	17	liver	liver	NOUN
dti-1548	253	18	donors	donor	NOUN
dti-1548	253	19	as	as	ADP
dti-1548	253	20	the	the	DET
dti-1548	253	21	control	control	NOUN
dti-1548	253	22	group	group	NOUN
dti-1548	253	23	.	.	PUNCT
dti-1548	254	1	on	on	ADP
dti-1548	254	2	the	the	DET
dti-1548	254	3	other	other	ADJ
dti-1548	254	4	hand	hand	NOUN
dti-1548	254	5	,	,	PUNCT
dti-1548	254	6	in	in	ADP
dti-1548	254	7	the	the	DET
dti-1548	254	8	vast	vast	ADJ
dti-1548	254	9	majority	majority	NOUN
dti-1548	254	10	of	of	ADP
dti-1548	254	11	studies	study	NOUN
dti-1548	254	12	paired	pair	VERB
dti-1548	254	13	adjacent	adjacent	ADJ
dti-1548	254	14	cirrhotic	cirrhotic	ADJ
dti-1548	254	15	liver	liver	NOUN
dti-1548	254	16	tissues	tissue	NOUN
dti-1548	254	17	to	to	ADP
dti-1548	254	18	the	the	DET
dti-1548	254	19	hcc	hcc	PROPN
dti-1548	254	20	tumor	tumor	NOUN
dti-1548	254	21	masses	masse	NOUN
dti-1548	254	22	were	be	AUX
dti-1548	254	23	used	use	VERB
dti-1548	254	24	as	as	ADP
dti-1548	254	25	controls	control	NOUN
dti-1548	254	26	(	(	PUNCT
dti-1548	254	27	30,45,67	30,45,67	NUM
dti-1548	254	28	–	–	PUNCT
dti-1548	254	29	69	69	NUM
dti-1548	254	30	)	)	PUNCT
dti-1548	254	31	.	.	PUNCT
dti-1548	255	1	this	this	PRON
dti-1548	255	2	complicates	complicate	VERB
dti-1548	255	3	the	the	DET
dti-1548	255	4	interpretation	interpretation	NOUN
dti-1548	255	5	of	of	ADP
dti-1548	255	6	results	result	NOUN
dti-1548	255	7	since	since	SCONJ
dti-1548	255	8	the	the	DET
dti-1548	255	9	gene	gene	NOUN
dti-1548	255	10	expression	expression	NOUN
dti-1548	255	11	patterns	pattern	NOUN
dti-1548	255	12	in	in	ADP
dti-1548	255	13	the	the	DET
dti-1548	255	14	nontumor	nontumor	PROPN
dti-1548	255	15	cirrhotic	cirrhotic	ADJ
dti-1548	255	16	liver	liver	NOUN
dti-1548	255	17	samples	sample	NOUN
dti-1548	255	18	from	from	ADP
dti-1548	255	19	different	different	ADJ
dti-1548	255	20	patients	patient	NOUN
dti-1548	255	21	can	can	AUX
dti-1548	255	22	vary	vary	VERB
dti-1548	255	23	significantly	significantly	ADV
dti-1548	255	24	,	,	PUNCT
dti-1548	255	25	affected	affect	VERB
dti-1548	255	26	by	by	ADP
dti-1548	255	27	the	the	DET
dti-1548	255	28	viral	viral	ADJ
dti-1548	255	29	infection	infection	NOUN
dti-1548	255	30	and	and	CCONJ
dti-1548	255	31	degree	degree	NOUN
dti-1548	255	32	of	of	ADP
dti-1548	255	33	fibrosis	fibrosis	NOUN
dti-1548	255	34	.	.	PUNCT
dti-1548	256	1	thus	thus	ADV
dti-1548	256	2	,	,	PUNCT
dti-1548	256	3	the	the	DET
dti-1548	256	4	tumor	tumor	NOUN
dti-1548	256	5	-	-	PUNCT
dti-1548	256	6	specific	specific	ADJ
dti-1548	256	7	variation	variation	NOUN
dti-1548	256	8	in	in	ADP
dti-1548	256	9	the	the	DET
dti-1548	256	10	expression	expression	NOUN
dti-1548	256	11	patterns	pattern	NOUN
dti-1548	256	12	could	could	AUX
dti-1548	256	13	not	not	PART
dti-1548	256	14	be	be	AUX
dti-1548	256	15	distinguished	distinguish	VERB
dti-1548	256	16	from	from	ADP
dti-1548	256	17	variation	variation	NOUN
dti-1548	256	18	due	due	ADP
dti-1548	256	19	to	to	ADP
dti-1548	256	20	differences	difference	NOUN
dti-1548	256	21	in	in	ADP
dti-1548	256	22	the	the	DET
dti-1548	256	23	corresponding	corresponding	ADJ
dti-1548	256	24	nontumor	nontumor	NOUN
dti-1548	256	25	liver	liver	NOUN
dti-1548	256	26	samples	sample	NOUN
dti-1548	256	27	(	(	PUNCT
dti-1548	256	28	70	70	NUM
dti-1548	256	29	)	)	PUNCT
dti-1548	256	30	.	.	PUNCT
dti-1548	257	1	in	in	ADP
dti-1548	257	2	our	our	PRON
dti-1548	257	3	cohort	cohort	NOUN
dti-1548	257	4	,	,	PUNCT
dti-1548	257	5	two	two	NUM
dti-1548	257	6	hkgs	hkgs	NOUN
dti-1548	257	7	–	–	PUNCT
dti-1548	257	8	b2	b2	NOUN
dti-1548	257	9	m	m	NOUN
dti-1548	257	10	and	and	CCONJ
dti-1548	257	11	hprt1	hprt1	NOUN
dti-1548	257	12	–	–	PUNCT
dti-1548	257	13	were	be	AUX
dti-1548	257	14	used	use	VERB
dti-1548	257	15	for	for	ADP
dti-1548	257	16	data	datum	NOUN
dti-1548	257	17	normalization	normalization	NOUN
dti-1548	257	18	.	.	PUNCT
dti-1548	258	1	in	in	ADP
dti-1548	258	2	a	a	DET
dti-1548	258	3	study	study	NOUN
dti-1548	258	4	performed	perform	VERB
dti-1548	258	5	to	to	PART
dti-1548	258	6	search	search	VERB
dti-1548	258	7	for	for	ADP
dti-1548	258	8	appropriate	appropriate	ADJ
dti-1548	258	9	hkgs	hkgs	NOUN
dti-1548	258	10	to	to	PART
dti-1548	258	11	be	be	AUX
dti-1548	258	12	used	use	VERB
dti-1548	258	13	for	for	ADP
dti-1548	258	14	data	datum	NOUN
dti-1548	258	15	normalization	normalization	NOUN
dti-1548	258	16	in	in	ADP
dti-1548	258	17	hcvinduced	hcvinduced	ADJ
dti-1548	258	18	hcc	hcc	PROPN
dti-1548	258	19	specifically	specifically	ADV
dti-1548	258	20	.	.	PUNCT
dti-1548	259	1	two	two	NUM
dti-1548	259	2	of	of	ADP
dti-1548	259	3	the	the	DET
dti-1548	259	4	most	most	ADV
dti-1548	259	5	commonly	commonly	ADV
dti-1548	259	6	used	use	VERB
dti-1548	259	7	hkgs	hkgs	NOUN
dti-1548	259	8	,	,	PUNCT
dti-1548	259	9	which	which	PRON
dti-1548	259	10	were	be	AUX
dti-1548	259	11	also	also	ADV
dti-1548	259	12	included	include	VERB
dti-1548	259	13	in	in	ADP
dti-1548	259	14	the	the	DET
dti-1548	259	15	standard	standard	NOUN
dti-1548	259	16	catalogued	catalogue	VERB
dti-1548	259	17	5	5	NUM
dti-1548	259	18	hkgs	hkgs	NOUN
dti-1548	259	19	set	set	VERB
dti-1548	259	20	in	in	ADP
dti-1548	259	21	the	the	DET
dti-1548	259	22	present	present	ADJ
dti-1548	259	23	study	study	NOUN
dti-1548	259	24	’s	’s	PART
dti-1548	259	25	array	array	NOUN
dti-1548	259	26	,	,	PUNCT
dti-1548	259	27	namely	namely	ADV
dti-1548	259	28	glyceraldehyde-3	glyceraldehyde-3	VERB
dti-1548	259	29	-	-	ADJ
dti-1548	259	30	phosphate	phosphate	ADJ
dti-1548	259	31	dehydrogenase	dehydrogenase	NOUN
dti-1548	259	32	(	(	PUNCT
dti-1548	259	33	gapdh	gapdh	NOUN
dti-1548	259	34	)	)	PUNCT
dti-1548	259	35	and	and	CCONJ
dti-1548	259	36	beta	beta	NOUN
dti-1548	259	37	-	-	PUNCT
dti-1548	259	38	actin	actin	NOUN
dti-1548	259	39	(	(	PUNCT
dti-1548	259	40	actb	actb	ADV
dti-1548	259	41	)	)	PUNCT
dti-1548	259	42	,	,	PUNCT
dti-1548	259	43	were	be	AUX
dti-1548	259	44	found	find	VERB
dti-1548	259	45	to	to	PART
dti-1548	259	46	be	be	AUX
dti-1548	259	47	deregulated	deregulate	VERB
dti-1548	259	48	in	in	ADP
dti-1548	259	49	hcv	hcv	NOUN
dti-1548	259	50	-	-	PUNCT
dti-1548	259	51	induced	induce	VERB
dti-1548	259	52	hcc	hcc	PROPN
dti-1548	259	53	(	(	PUNCT
dti-1548	259	54	71	71	NUM
dti-1548	259	55	)	)	PUNCT
dti-1548	259	56	.	.	PUNCT
dti-1548	260	1	thus	thus	ADV
dti-1548	260	2	,	,	PUNCT
dti-1548	260	3	using	use	VERB
dti-1548	260	4	them	they	PRON
dti-1548	260	5	for	for	ADP
dti-1548	260	6	normalization	normalization	NOUN
dti-1548	260	7	would	would	AUX
dti-1548	260	8	have	have	VERB
dti-1548	260	9	strong	strong	ADJ
dti-1548	260	10	effects	effect	NOUN
dti-1548	260	11	on	on	ADP
dti-1548	260	12	the	the	DET
dti-1548	260	13	extent	extent	NOUN
dti-1548	260	14	of	of	ADP
dti-1548	260	15	differential	differential	ADJ
dti-1548	260	16	expression	expression	NOUN
dti-1548	260	17	of	of	ADP
dti-1548	260	18	genes	gene	NOUN
dti-1548	260	19	,	,	PUNCT
dti-1548	260	20	leading	lead	VERB
dti-1548	260	21	to	to	ADP
dti-1548	260	22	misinterpretation	misinterpretation	NOUN
dti-1548	260	23	of	of	ADP
dti-1548	260	24	results	result	NOUN
dti-1548	260	25	.	.	PUNCT
dti-1548	261	1	this	this	PRON
dti-1548	261	2	was	be	AUX
dti-1548	261	3	the	the	DET
dti-1548	261	4	exact	exact	ADJ
dti-1548	261	5	same	same	ADJ
dti-1548	261	6	case	case	NOUN
dti-1548	261	7	in	in	ADP
dti-1548	261	8	our	our	PRON
dti-1548	261	9	study	study	NOUN
dti-1548	261	10	for	for	ADP
dti-1548	261	11	actb	actb	NOUN
dti-1548	261	12	and	and	CCONJ
dti-1548	261	13	gapdh	gapdh	NOUN
dti-1548	261	14	,	,	PUNCT
dti-1548	261	15	which	which	PRON
dti-1548	261	16	were	be	AUX
dti-1548	261	17	found	find	VERB
dti-1548	261	18	to	to	PART
dti-1548	261	19	be	be	AUX
dti-1548	261	20	unstable	unstable	ADJ
dti-1548	261	21	and	and	CCONJ
dti-1548	261	22	had	have	VERB
dti-1548	261	23	a	a	DET
dti-1548	261	24	wide	wide	ADJ
dti-1548	261	25	sd	sd	NOUN
dti-1548	261	26	across	across	ADP
dti-1548	261	27	samples	sample	NOUN
dti-1548	261	28	.	.	PUNCT
dti-1548	262	1	a	a	DET
dti-1548	262	2	few	few	ADJ
dti-1548	262	3	weaknesses	weakness	NOUN
dti-1548	262	4	of	of	ADP
dti-1548	262	5	this	this	DET
dti-1548	262	6	study	study	NOUN
dti-1548	262	7	that	that	PRON
dti-1548	262	8	we	we	PRON
dti-1548	262	9	recognize	recognize	VERB
dti-1548	262	10	are	be	AUX
dti-1548	262	11	,	,	PUNCT
dti-1548	262	12	firstly	firstly	ADV
dti-1548	262	13	,	,	PUNCT
dti-1548	262	14	the	the	DET
dti-1548	262	15	fact	fact	NOUN
dti-1548	262	16	that	that	SCONJ
dti-1548	262	17	we	we	PRON
dti-1548	262	18	were	be	AUX
dti-1548	262	19	studying	study	VERB
dti-1548	262	20	patients	patient	NOUN
dti-1548	262	21	who	who	PRON
dti-1548	262	22	already	already	ADV
dti-1548	262	23	had	have	AUX
dti-1548	262	24	developed	develop	VERB
dti-1548	262	25	disease	disease	NOUN
dti-1548	262	26	at	at	ADP
dti-1548	262	27	a	a	DET
dti-1548	262	28	single	single	ADJ
dti-1548	262	29	point	point	NOUN
dti-1548	262	30	in	in	ADP
dti-1548	262	31	time	time	NOUN
dti-1548	262	32	.	.	PUNCT
dti-1548	263	1	also	also	ADV
dti-1548	263	2	,	,	PUNCT
dti-1548	263	3	as	as	ADP
dti-1548	263	4	in	in	ADP
dti-1548	263	5	most	most	ADJ
dti-1548	263	6	studies	study	NOUN
dti-1548	263	7	on	on	ADP
dti-1548	263	8	hcc	hcc	PROPN
dti-1548	263	9	,	,	PUNCT
dti-1548	263	10	tumor	tumor	NOUN
dti-1548	263	11	samples	sample	NOUN
dti-1548	263	12	have	have	AUX
dti-1548	263	13	been	be	AUX
dti-1548	263	14	collected	collect	VERB
dti-1548	263	15	during	during	ADP
dti-1548	263	16	resection	resection	NOUN
dti-1548	263	17	.	.	PUNCT
dti-1548	264	1	it	it	PRON
dti-1548	264	2	could	could	AUX
dti-1548	264	3	be	be	AUX
dti-1548	264	4	expected	expect	VERB
dti-1548	264	5	that	that	SCONJ
dti-1548	264	6	in	in	ADP
dti-1548	264	7	a	a	DET
dti-1548	264	8	more	more	ADV
dti-1548	264	9	clinically	clinically	ADV
dti-1548	264	10	advanced	advanced	ADJ
dti-1548	264	11	context	context	NOUN
dti-1548	264	12	with	with	ADP
dti-1548	264	13	tumor	tumor	NOUN
dti-1548	264	14	progression	progression	NOUN
dti-1548	264	15	,	,	PUNCT
dti-1548	264	16	increased	increase	VERB
dti-1548	264	17	crosstalk	crosstalk	NOUN
dti-1548	264	18	among	among	ADP
dti-1548	264	19	pathways	pathway	NOUN
dti-1548	264	20	and	and	CCONJ
dti-1548	264	21	chromosomal	chromosomal	ADJ
dti-1548	264	22	instability	instability	NOUN
dti-1548	264	23	would	would	AUX
dti-1548	264	24	contribute	contribute	VERB
dti-1548	264	25	to	to	ADP
dti-1548	264	26	additional	additional	ADJ
dti-1548	264	27	signaling	signal	VERB
dti-1548	264	28	deregulation	deregulation	NOUN
dti-1548	264	29	.	.	PUNCT
dti-1548	265	1	these	these	DET
dti-1548	265	2	samples	sample	NOUN
dti-1548	265	3	do	do	AUX
dti-1548	265	4	not	not	PART
dti-1548	265	5	represent	represent	VERB
dti-1548	265	6	the	the	DET
dti-1548	265	7	tumors	tumor	NOUN
dti-1548	265	8	of	of	ADP
dti-1548	265	9	patients	patient	NOUN
dti-1548	265	10	with	with	ADP
dti-1548	265	11	advanced	advanced	ADJ
dti-1548	265	12	stage	stage	NOUN
dti-1548	265	13	disease	disease	NOUN
dti-1548	265	14	,	,	PUNCT
dti-1548	265	15	who	who	PRON
dti-1548	265	16	do	do	AUX
dti-1548	265	17	not	not	PART
dti-1548	265	18	undergo	undergo	VERB
dti-1548	265	19	surgery	surgery	NOUN
dti-1548	265	20	.	.	PUNCT
dti-1548	266	1	however	however	ADV
dti-1548	266	2	,	,	PUNCT
dti-1548	266	3	as	as	SCONJ
dti-1548	266	4	hcc	hcc	PROPN
dti-1548	266	5	diagnosis	diagnosis	NOUN
dti-1548	266	6	at	at	ADP
dti-1548	266	7	present	present	ADJ
dti-1548	266	8	is	be	AUX
dti-1548	266	9	not	not	PART
dti-1548	266	10	tissue	tissue	NOUN
dti-1548	266	11	based	base	VERB
dti-1548	266	12	,	,	PUNCT
dti-1548	266	13	obtaining	obtain	VERB
dti-1548	266	14	tissue	tissue	NOUN
dti-1548	266	15	samples	sample	NOUN
dti-1548	266	16	from	from	ADP
dti-1548	266	17	late	late	ADJ
dti-1548	266	18	cases	case	NOUN
dti-1548	266	19	is	be	AUX
dti-1548	266	20	not	not	PART
dti-1548	266	21	feasible	feasible	ADJ
dti-1548	266	22	at	at	ADP
dti-1548	266	23	present	present	ADJ
dti-1548	266	24	.	.	PUNCT
dti-1548	267	1	conclusions	conclusion	NOUN
dti-1548	267	2	the	the	DET
dti-1548	267	3	significantly	significantly	ADV
dti-1548	267	4	upand	upand	PROPN
dti-1548	267	5	downregulated	downregulate	VERB
dti-1548	267	6	genes	gene	NOUN
dti-1548	267	7	identified	identify	VERB
dti-1548	267	8	in	in	ADP
dti-1548	267	9	the	the	DET
dti-1548	267	10	present	present	ADJ
dti-1548	267	11	study	study	NOUN
dti-1548	267	12	can	can	AUX
dti-1548	267	13	serve	serve	VERB
dti-1548	267	14	as	as	ADP
dti-1548	267	15	potential	potential	ADJ
dti-1548	267	16	therapeutic	therapeutic	ADJ
dti-1548	267	17	targets	target	NOUN
dti-1548	267	18	for	for	ADP
dti-1548	267	19	hcv	hcv	NOUN
dti-1548	267	20	-	-	PUNCT
dti-1548	267	21	related	relate	VERB
dti-1548	267	22	hccs	hccs	NOUN
dti-1548	267	23	.	.	PUNCT
dti-1548	268	1	in	in	ADP
dti-1548	268	2	the	the	DET
dti-1548	268	3	present	present	ADJ
dti-1548	268	4	study	study	NOUN
dti-1548	268	5	,	,	PUNCT
dti-1548	268	6	the	the	DET
dti-1548	268	7	insulin	insulin	NOUN
dti-1548	268	8	pathway	pathway	NOUN
dti-1548	268	9	genes	gene	NOUN
dti-1548	268	10	including	include	VERB
dti-1548	268	11	igf1r	igf1r	PROPN
dti-1548	268	12	,	,	PUNCT
dti-1548	268	13	igf2	igf2	PROPN
dti-1548	268	14	,	,	PUNCT
dti-1548	268	15	ins	in	NOUN
dti-1548	268	16	,	,	PUNCT
dti-1548	268	17	insr	insr	NOUN
dti-1548	268	18	,	,	PUNCT
dti-1548	268	19	and	and	CCONJ
dti-1548	268	20	irs1	irs1	NOUN
dti-1548	268	21	were	be	AUX
dti-1548	268	22	found	find	VERB
dti-1548	268	23	to	to	PART
dti-1548	268	24	be	be	AUX
dti-1548	268	25	downregulated	downregulate	VERB
dti-1548	268	26	and	and	CCONJ
dti-1548	268	27	the	the	DET
dti-1548	268	28	igf	igf	PROPN
dti-1548	268	29	pathway	pathway	NOUN
dti-1548	268	30	was	be	AUX
dti-1548	268	31	found	find	VERB
dti-1548	268	32	to	to	PART
dti-1548	268	33	be	be	AUX
dti-1548	268	34	significantly	significantly	ADV
dti-1548	268	35	inactive	inactive	ADJ
dti-1548	268	36	,	,	PUNCT
dti-1548	268	37	in	in	ADP
dti-1548	268	38	the	the	DET
dti-1548	268	39	present	present	ADJ
dti-1548	268	40	work	work	NOUN
dti-1548	268	41	,	,	PUNCT
dti-1548	268	42	which	which	PRON
dti-1548	268	43	is	be	AUX
dti-1548	268	44	in	in	ADP
dti-1548	268	45	concordance	concordance	NOUN
dti-1548	268	46	with	with	ADP
dti-1548	268	47	the	the	DET
dti-1548	268	48	findings	finding	NOUN
dti-1548	268	49	of	of	ADP
dti-1548	268	50	zucman	zucman	NOUN
dti-1548	268	51	-	-	PUNCT
dti-1548	268	52	rossi	rossi	PROPN
dti-1548	268	53	et	et	PROPN
dti-1548	268	54	al	al	PROPN
dti-1548	268	55	(	(	PUNCT
dti-1548	268	56	72	72	NUM
dti-1548	268	57	)	)	PUNCT
dti-1548	268	58	.	.	PUNCT
dti-1548	269	1	therefore	therefore	ADV
dti-1548	269	2	,	,	PUNCT
dti-1548	269	3	drugs	drug	NOUN
dti-1548	269	4	targeting	target	VERB
dti-1548	269	5	the	the	DET
dti-1548	269	6	igf1r	igf1r	ADJ
dti-1548	269	7	pathway	pathway	NOUN
dti-1548	269	8	may	may	AUX
dti-1548	269	9	not	not	PART
dti-1548	269	10	be	be	AUX
dti-1548	269	11	suitable	suitable	ADJ
dti-1548	269	12	for	for	ADP
dti-1548	269	13	this	this	DET
dti-1548	269	14	specific	specific	ADJ
dti-1548	269	15	subset	subset	NOUN
dti-1548	269	16	of	of	ADP
dti-1548	269	17	hcv	hcv	NOUN
dti-1548	269	18	-	-	PUNCT
dti-1548	269	19	related	relate	VERB
dti-1548	269	20	hccs	hccs	NOUN
dti-1548	269	21	.	.	PUNCT
dti-1548	270	1	although	although	SCONJ
dti-1548	270	2	nos2	nos2	PROPN
dti-1548	270	3	gene	gene	NOUN
dti-1548	270	4	expression	expression	NOUN
dti-1548	270	5	was	be	AUX
dti-1548	270	6	unchanged	unchanged	ADJ
dti-1548	270	7	in	in	ADP
dti-1548	270	8	our	our	PRON
dti-1548	270	9	cohort	cohort	NOUN
dti-1548	270	10	,	,	PUNCT
dti-1548	270	11	ipa	ipa	PROPN
dti-1548	270	12	revealed	reveal	VERB
dti-1548	270	13	that	that	SCONJ
dti-1548	270	14	nitric	nitric	ADJ
dti-1548	270	15	oxide	oxide	NOUN
dti-1548	270	16	pathway	pathway	NOUN
dti-1548	270	17	and	and	CCONJ
dti-1548	270	18	reactive	reactive	ADJ
dti-1548	270	19	oxygen	oxygen	NOUN
dti-1548	270	20	species	species	NOUN
dti-1548	270	21	production	production	NOUN
dti-1548	270	22	in	in	ADP
dti-1548	270	23	hcv	hcv	NOUN
dti-1548	270	24	-	-	PUNCT
dti-1548	270	25	related	relate	VERB
dti-1548	270	26	hccs	hccs	NOUN
dti-1548	270	27	were	be	AUX
dti-1548	270	28	significantly	significantly	ADV
dti-1548	270	29	activated	activate	VERB
dti-1548	270	30	.	.	PUNCT
dti-1548	271	1	the	the	DET
dti-1548	271	2	gene	gene	NOUN
dti-1548	271	3	expression	expression	NOUN
dti-1548	271	4	pattern	pattern	NOUN
dti-1548	271	5	of	of	ADP
dti-1548	271	6	each	each	DET
dti-1548	271	7	hcc	hcc	PROPN
dti-1548	271	8	tumor	tumor	NOUN
dti-1548	271	9	seems	seem	VERB
dti-1548	271	10	to	to	PART
dti-1548	271	11	provide	provide	VERB
dti-1548	271	12	a	a	DET
dti-1548	271	13	distinctive	distinctive	ADJ
dti-1548	271	14	molecular	molecular	ADJ
dti-1548	271	15	portrait	portrait	NOUN
dti-1548	271	16	of	of	ADP
dti-1548	271	17	that	that	DET
dti-1548	271	18	tumor	tumor	NOUN
dti-1548	271	19	,	,	PUNCT
dti-1548	271	20	as	as	SCONJ
dti-1548	271	21	no	no	DET
dti-1548	271	22	gene	gene	NOUN
dti-1548	271	23	was	be	AUX
dti-1548	271	24	100	100	NUM
dti-1548	271	25	%	%	NOUN
dti-1548	271	26	upor	upor	NOUN
dti-1548	271	27	downregulated	downregulate	VERB
dti-1548	271	28	in	in	ADP
dti-1548	271	29	the	the	DET
dti-1548	271	30	present	present	ADJ
dti-1548	271	31	cohort	cohort	NOUN
dti-1548	271	32	.	.	PUNCT
dti-1548	272	1	personalized	personalized	ADJ
dti-1548	272	2	medicine	medicine	NOUN
dti-1548	272	3	mandates	mandate	VERB
dti-1548	272	4	the	the	DET
dti-1548	272	5	knowledge	knowledge	NOUN
dti-1548	272	6	of	of	ADP
dti-1548	272	7	the	the	DET
dti-1548	272	8	specific	specific	ADJ
dti-1548	272	9	genetic	genetic	ADJ
dti-1548	272	10	profile	profile	NOUN
dti-1548	272	11	of	of	ADP
dti-1548	272	12	each	each	DET
dti-1548	272	13	hcc	hcc	PROPN
dti-1548	272	14	tumor	tumor	NOUN
dti-1548	272	15	,	,	PUNCT
dti-1548	272	16	which	which	PRON
dti-1548	272	17	is	be	AUX
dti-1548	272	18	currently	currently	ADV
dti-1548	272	19	not	not	PART
dti-1548	272	20	feasible	feasible	ADJ
dti-1548	272	21	due	due	ADP
dti-1548	272	22	to	to	ADP
dti-1548	272	23	costs	cost	NOUN
dti-1548	272	24	associated	associate	VERB
dti-1548	272	25	especially	especially	ADV
dti-1548	272	26	in	in	ADP
dti-1548	272	27	developing	develop	VERB
dti-1548	272	28	countries	country	NOUN
dti-1548	272	29	where	where	SCONJ
dti-1548	272	30	most	most	ADJ
dti-1548	272	31	of	of	ADP
dti-1548	272	32	the	the	DET
dti-1548	272	33	hcc	hcc	PROPN
dti-1548	272	34	burden	burden	NOUN
dti-1548	272	35	lies	lie	NOUN
dti-1548	272	36	.	.	PUNCT
dti-1548	273	1	therefore	therefore	ADV
dti-1548	273	2	,	,	PUNCT
dti-1548	273	3	the	the	DET
dti-1548	273	4	present	present	ADJ
dti-1548	273	5	study	study	NOUN
dti-1548	273	6	fills	fill	VERB
dti-1548	273	7	a	a	DET
dti-1548	273	8	void	void	NOUN
dti-1548	273	9	in	in	ADP
dti-1548	273	10	this	this	DET
dti-1548	273	11	respect	respect	NOUN
dti-1548	273	12	–	–	PUNCT
dti-1548	273	13	identifying	identify	VERB
dti-1548	273	14	specific	specific	ADJ
dti-1548	273	15	morphologic	morphologic	ADJ
dti-1548	273	16	and	and	CCONJ
dti-1548	273	17	clinical	clinical	ADJ
dti-1548	273	18	patient	patient	NOUN
dti-1548	273	19	/	/	SYM
dti-1548	273	20	tumor	tumor	NOUN
dti-1548	273	21	characteristics	characteristic	NOUN
dti-1548	273	22	,	,	PUNCT
dti-1548	273	23	which	which	PRON
dti-1548	273	24	significantly	significantly	ADV
dti-1548	273	25	correlate	correlate	VERB
dti-1548	273	26	with	with	ADP
dti-1548	273	27	underlying	underlie	VERB
dti-1548	273	28	molecular	molecular	ADJ
dti-1548	273	29	alterations	alteration	NOUN
dti-1548	273	30	.	.	PUNCT
dti-1548	274	1	this	this	PRON
dti-1548	274	2	may	may	AUX
dti-1548	274	3	be	be	AUX
dti-1548	274	4	used	use	VERB
dti-1548	274	5	as	as	ADP
dti-1548	274	6	a	a	DET
dti-1548	274	7	guide	guide	NOUN
dti-1548	274	8	for	for	ADP
dti-1548	274	9	tailoring	tailor	VERB
dti-1548	274	10	molecularly	molecularly	ADV
dti-1548	274	11	targeted	target	VERB
dti-1548	274	12	therapies	therapy	NOUN
dti-1548	274	13	.	.	PUNCT
dti-1548	275	1	we	we	PRON
dti-1548	275	2	confirm	confirm	VERB
dti-1548	275	3	the	the	DET
dti-1548	275	4	findings	finding	NOUN
dti-1548	275	5	of	of	ADP
dti-1548	275	6	a	a	DET
dti-1548	275	7	previous	previous	ADJ
dti-1548	275	8	study	study	NOUN
dti-1548	275	9	that	that	PRON
dti-1548	275	10	was	be	AUX
dti-1548	275	11	performed	perform	VERB
dti-1548	275	12	to	to	PART
dti-1548	275	13	search	search	VERB
dti-1548	275	14	for	for	ADP
dti-1548	275	15	appropriate	appropriate	ADJ
dti-1548	275	16	hkgs	hkgs	NOUN
dti-1548	275	17	to	to	PART
dti-1548	275	18	be	be	AUX
dti-1548	275	19	used	use	VERB
dti-1548	275	20	for	for	ADP
dti-1548	275	21	data	datum	NOUN
dti-1548	275	22	normalization	normalization	NOUN
dti-1548	275	23	in	in	ADP
dti-1548	275	24	hcv	hcv	NOUN
dti-1548	275	25	-	-	PUNCT
dti-1548	275	26	induced	induce	VERB
dti-1548	275	27	hcc	hcc	PROPN
dti-1548	275	28	specifically	specifically	ADV
dti-1548	275	29	.	.	PUNCT
dti-1548	276	1	two	two	NUM
dti-1548	276	2	of	of	ADP
dti-1548	276	3	the	the	DET
dti-1548	276	4	most	most	ADV
dti-1548	276	5	commonly	commonly	ADV
dti-1548	276	6	used	use	VERB
dti-1548	276	7	hkgs	hkgs	NOUN
dti-1548	276	8	–	–	PUNCT
dti-1548	276	9	actb	actb	NOUN
dti-1548	276	10	and	and	CCONJ
dti-1548	276	11	gapdh	gapdh	NOUN
dti-1548	276	12	–	–	PUNCT
dti-1548	276	13	were	be	AUX
dti-1548	276	14	found	find	VERB
dti-1548	276	15	to	to	PART
dti-1548	276	16	be	be	AUX
dti-1548	276	17	unstable	unstable	ADJ
dti-1548	276	18	and	and	CCONJ
dti-1548	276	19	had	have	VERB
dti-1548	276	20	a	a	DET
dti-1548	276	21	wide	wide	ADJ
dti-1548	276	22	sd	sd	NOUN
dti-1548	276	23	in	in	ADP
dti-1548	276	24	our	our	PRON
dti-1548	276	25	study	study	NOUN
dti-1548	276	26	and	and	CCONJ
dti-1548	276	27	theirs	theirs	PRON
dti-1548	276	28	;	;	PUNCT
dti-1548	276	29	therefore	therefore	ADV
dti-1548	276	30	these	these	PRON
dti-1548	276	31	should	should	AUX
dti-1548	276	32	n’t	not	PART
dti-1548	276	33	be	be	AUX
dti-1548	276	34	used	use	VERB
dti-1548	276	35	for	for	ADP
dti-1548	276	36	normalization	normalization	NOUN
dti-1548	276	37	.	.	PUNCT
dti-1548	277	1	we	we	PRON
dti-1548	277	2	suggest	suggest	VERB
dti-1548	277	3	b2	b2	NOUN
dti-1548	277	4	m	m	PROPN
dti-1548	277	5	and	and	CCONJ
dti-1548	277	6	hprt1	hprt1	NOUN
dti-1548	277	7	to	to	PART
dti-1548	277	8	be	be	AUX
dti-1548	277	9	used	use	VERB
dti-1548	277	10	instead	instead	ADV
dti-1548	277	11	,	,	PUNCT
dti-1548	277	12	as	as	SCONJ
dti-1548	277	13	they	they	PRON
dti-1548	277	14	had	have	VERB
dti-1548	277	15	more	more	ADJ
dti-1548	277	16	stable	stable	ADJ
dti-1548	277	17	levels	level	NOUN
dti-1548	277	18	of	of	ADP
dti-1548	277	19	expression	expression	NOUN
dti-1548	277	20	.	.	PUNCT
dti-1548	278	1	disclosures	disclosure	VERB
dti-1548	278	2	financial	financial	ADJ
dti-1548	278	3	support	support	NOUN
dti-1548	278	4	:	:	PUNCT
dti-1548	278	5	the	the	DET
dti-1548	278	6	present	present	ADJ
dti-1548	278	7	study	study	NOUN
dti-1548	278	8	was	be	AUX
dti-1548	278	9	fully	fully	ADV
dti-1548	278	10	funded	fund	VERB
dti-1548	278	11	by	by	ADP
dti-1548	278	12	a	a	DET
dti-1548	278	13	grant	grant	NOUN
dti-1548	278	14	from	from	ADP
dti-1548	278	15	the	the	DET
dti-1548	278	16	“	"	PUNCT
dti-1548	278	17	alexandria	alexandria	PROPN
dti-1548	278	18	regional	regional	ADJ
dti-1548	278	19	center	center	NOUN
dti-1548	278	20	for	for	ADP
dti-1548	278	21	women	woman	NOUN
dti-1548	278	22	’s	’s	PART
dti-1548	278	23	health	health	NOUN
dti-1548	278	24	and	and	CCONJ
dti-1548	278	25	development	development	NOUN
dti-1548	278	26	,	,	PUNCT
dti-1548	278	27	”	"	PUNCT
dti-1548	278	28	alexandria	alexandria	PROPN
dti-1548	278	29	,	,	PUNCT
dti-1548	278	30	egypt	egypt	PROPN
dti-1548	278	31	(	(	PUNCT
dti-1548	278	32	this	this	DET
dti-1548	278	33	grant	grant	NOUN
dti-1548	278	34	covered	cover	VERB
dti-1548	278	35	all	all	DET
dti-1548	278	36	expenses	expense	NOUN
dti-1548	278	37	needed	need	VERB
dti-1548	278	38	for	for	ADP
dti-1548	278	39	provision	provision	NOUN
dti-1548	278	40	of	of	ADP
dti-1548	278	41	all	all	DET
dti-1548	278	42	experimental	experimental	ADJ
dti-1548	278	43	kits	kit	NOUN
dti-1548	278	44	)	)	PUNCT
dti-1548	278	45	.	.	PUNCT
dti-1548	279	1	conflict	conflict	NOUN
dti-1548	279	2	of	of	ADP
dti-1548	279	3	interest	interest	NOUN
dti-1548	279	4	:	:	PUNCT
dti-1548	279	5	all	all	DET
dti-1548	279	6	the	the	DET
dti-1548	279	7	authors	author	NOUN
dti-1548	279	8	declare	declare	VERB
dti-1548	279	9	no	no	DET
dti-1548	279	10	conflict	conflict	NOUN
dti-1548	279	11	of	of	ADP
dti-1548	279	12	interest	interest	NOUN
dti-1548	279	13	.	.	PUNCT
dti-1548	280	1	references	reference	NOUN
dti-1548	280	2	1	1	NUM
dti-1548	280	3	.	.	PUNCT
dti-1548	280	4	international	international	ADJ
dti-1548	280	5	agency	agency	NOUN
dti-1548	280	6	for	for	ADP
dti-1548	280	7	research	research	NOUN
dti-1548	280	8	on	on	ADP
dti-1548	280	9	cancer	cancer	NOUN
dti-1548	280	10	(	(	PUNCT
dti-1548	280	11	iarc	iarc	NOUN
dti-1548	280	12	)	)	PUNCT
dti-1548	280	13	.	.	PUNCT
dti-1548	281	1	globocan	globocan	PROPN
dti-1548	281	2	2012	2012	NUM
dti-1548	281	3	:	:	PUNCT
dti-1548	281	4	estimated	estimate	VERB
dti-1548	281	5	cancer	cancer	NOUN
dti-1548	281	6	incidence	incidence	NOUN
dti-1548	281	7	,	,	PUNCT
dti-1548	281	8	mortality	mortality	NOUN
dti-1548	281	9	and	and	CCONJ
dti-1548	281	10	prevalence	prevalence	NOUN
dti-1548	281	11	worldwide	worldwide	ADV
dti-1548	281	12	in	in	ADP
dti-1548	281	13	2012	2012	NUM
dti-1548	281	14	.	.	PUNCT
dti-1548	282	1	france	france	PROPN
dti-1548	282	2	:	:	PUNCT
dti-1548	282	3	iarc	iarc	PROPN
dti-1548	282	4	;	;	PUNCT
dti-1548	282	5	2012	2012	NUM
dti-1548	282	6	.	.	PUNCT
dti-1548	283	1	2	2	X
dti-1548	283	2	.	.	X
dti-1548	283	3	shi	shi	PROPN
dti-1548	283	4	j	j	PROPN
dti-1548	283	5	,	,	PUNCT
dti-1548	283	6	zhu	zhu	PROPN
dti-1548	283	7	l	l	PROPN
dti-1548	283	8	,	,	PUNCT
dti-1548	283	9	liu	liu	PROPN
dti-1548	283	10	s	s	PROPN
dti-1548	283	11	,	,	PUNCT
dti-1548	283	12	xie	xie	PROPN
dti-1548	283	13	wf	wf	PROPN
dti-1548	283	14	.	.	PUNCT
dti-1548	284	1	a	a	DET
dti-1548	284	2	meta	meta	ADJ
dti-1548	284	3	-	-	PUNCT
dti-1548	284	4	analysis	analysis	NOUN
dti-1548	284	5	of	of	ADP
dti-1548	284	6	case	case	NOUN
dti-1548	284	7	-	-	PUNCT
dti-1548	284	8	control	control	NOUN
dti-1548	284	9	studies	study	NOUN
dti-1548	284	10	on	on	ADP
dti-1548	284	11	the	the	DET
dti-1548	284	12	combined	combine	VERB
dti-1548	284	13	effect	effect	NOUN
dti-1548	284	14	of	of	ADP
dti-1548	284	15	hepatitis	hepatitis	PROPN
dti-1548	284	16	b	b	PROPN
dti-1548	284	17	and	and	CCONJ
dti-1548	284	18	c	c	PROPN
dti-1548	284	19	virus	virus	NOUN
dti-1548	284	20	infections	infection	NOUN
dti-1548	284	21	in	in	ADP
dti-1548	284	22	causing	cause	VERB
dti-1548	284	23	hepatocellular	hepatocellular	ADJ
dti-1548	284	24	carcinoma	carcinoma	NOUN
dti-1548	284	25	in	in	ADP
dti-1548	284	26	china	china	PROPN
dti-1548	284	27	.	.	PUNCT
dti-1548	285	1	br	br	PROPN
dti-1548	285	2	j	j	PROPN
dti-1548	285	3	cancer	cancer	NOUN
dti-1548	285	4	.	.	PUNCT
dti-1548	286	1	2005;92(3):607–612	2005;92(3):607–612	NUM
dti-1548	286	2	.	.	NOUN
dti-1548	286	3	3	3	X
dti-1548	286	4	.	.	X
dti-1548	286	5	llovet	llovet	PROPN
dti-1548	286	6	jm	jm	PROPN
dti-1548	286	7	,	,	PUNCT
dti-1548	286	8	villanueva	villanueva	PROPN
dti-1548	286	9	a	a	PRON
dti-1548	286	10	,	,	PUNCT
dti-1548	286	11	lachenmayer	lachenmayer	NOUN
dti-1548	286	12	a	a	NOUN
dti-1548	286	13	,	,	PUNCT
dti-1548	286	14	finn	finn	PROPN
dti-1548	286	15	rs	rs	PROPN
dti-1548	286	16	.	.	PUNCT
dti-1548	287	1	advances	advance	NOUN
dti-1548	287	2	in	in	ADP
dti-1548	287	3	targeted	target	VERB
dti-1548	287	4	therapies	therapy	NOUN
dti-1548	287	5	for	for	ADP
dti-1548	287	6	hepatocellular	hepatocellular	ADJ
dti-1548	287	7	carcinoma	carcinoma	NOUN
dti-1548	287	8	in	in	ADP
dti-1548	287	9	the	the	DET
dti-1548	287	10	genomic	genomic	ADJ
dti-1548	287	11	era	era	NOUN
dti-1548	287	12	.	.	PUNCT
dti-1548	288	1	nat	nat	PROPN
dti-1548	288	2	rev	rev	VERB
dti-1548	288	3	clin	clin	PROPN
dti-1548	288	4	oncol	oncol	PROPN
dti-1548	288	5	.	.	PUNCT
dti-1548	289	1	2015;12(7):408–424	2015;12(7):408–424	NUM
dti-1548	289	2	.	.	NOUN
dti-1548	289	3	4	4	NUM
dti-1548	289	4	.	.	X
dti-1548	290	1	el	el	PROPN
dti-1548	290	2	-	-	PUNCT
dti-1548	290	3	zanaty	zanaty	NOUN
dti-1548	290	4	f	f	NOUN
dti-1548	290	5	,	,	PUNCT
dti-1548	290	6	way	way	ADV
dti-1548	290	7	a.	a.	PROPN
dti-1548	290	8	egypt	egypt	PROPN
dti-1548	290	9	demographic	demographic	ADJ
dti-1548	290	10	and	and	CCONJ
dti-1548	290	11	health	health	NOUN
dti-1548	290	12	survey	survey	NOUN
dti-1548	290	13	2008	2008	NUM
dti-1548	290	14	.	.	PUNCT
dti-1548	291	1	cairo	cairo	PROPN
dti-1548	291	2	,	,	PUNCT
dti-1548	291	3	egypt	egypt	PROPN
dti-1548	291	4	:	:	PUNCT
dti-1548	291	5	ministry	ministry	PROPN
dti-1548	291	6	of	of	ADP
dti-1548	291	7	health	health	PROPN
dti-1548	291	8	,	,	PUNCT
dti-1548	291	9	el	el	PROPN
dti-1548	291	10	-	-	PUNCT
dti-1548	291	11	zanaty	zanaty	PROPN
dti-1548	291	12	and	and	CCONJ
dti-1548	291	13	associates	associate	NOUN
dti-1548	291	14	,	,	PUNCT
dti-1548	291	15	and	and	CCONJ
dti-1548	291	16	macro	macro	ADJ
dti-1548	291	17	international	international	ADJ
dti-1548	291	18	;	;	PUNCT
dti-1548	291	19	2009	2009	NUM
dti-1548	291	20	.	.	PUNCT
dti-1548	292	1	5	5	X
dti-1548	292	2	.	.	X
dti-1548	292	3	maucort	maucort	NOUN
dti-1548	292	4	-	-	PUNCT
dti-1548	292	5	boulch	boulch	PROPN
dti-1548	292	6	d	d	PROPN
dti-1548	292	7	,	,	PUNCT
dti-1548	292	8	de	de	PROPN
dti-1548	292	9	martel	martel	PROPN
dti-1548	292	10	c	c	X
dti-1548	292	11	,	,	PUNCT
dti-1548	292	12	franceschi	franceschi	PROPN
dti-1548	292	13	s	s	PROPN
dti-1548	292	14	,	,	PUNCT
dti-1548	292	15	plummer	plummer	PROPN
dti-1548	292	16	m.	m.	NOUN
dti-1548	292	17	fraction	fraction	NOUN
dti-1548	292	18	and	and	CCONJ
dti-1548	292	19	incidence	incidence	NOUN
dti-1548	292	20	of	of	ADP
dti-1548	292	21	liver	liver	NOUN
dti-1548	292	22	cancer	cancer	NOUN
dti-1548	292	23	attributable	attributable	ADJ
dti-1548	292	24	to	to	ADP
dti-1548	292	25	hepatitis	hepatitis	PROPN
dti-1548	292	26	b	b	PROPN
dti-1548	292	27	and	and	CCONJ
dti-1548	292	28	c	c	PROPN
dti-1548	292	29	viruses	virus	NOUN
dti-1548	292	30	worldwide	worldwide	ADV
dti-1548	292	31	.	.	PUNCT
dti-1548	293	1	int	int	NOUN
dti-1548	293	2	j	j	PROPN
dti-1548	293	3	cancer	cancer	NOUN
dti-1548	293	4	.	.	PUNCT
dti-1548	294	1	2018;142(12):2471	2018;142(12):2471	NUM
dti-1548	294	2	-	-	SYM
dti-1548	294	3	7	7	NUM
dti-1548	294	4	.	.	NOUN
dti-1548	294	5	6	6	NUM
dti-1548	294	6	.	.	X
dti-1548	294	7	ray	ray	PROPN
dti-1548	294	8	sc	sc	PROPN
dti-1548	294	9	,	,	PUNCT
dti-1548	294	10	arthur	arthur	PROPN
dti-1548	294	11	rr	rr	PROPN
dti-1548	294	12	,	,	PUNCT
dti-1548	294	13	carella	carella	PROPN
dti-1548	294	14	a	a	PROPN
dti-1548	294	15	,	,	PUNCT
dti-1548	294	16	bukh	bukh	PROPN
dti-1548	294	17	j	j	PROPN
dti-1548	294	18	,	,	PUNCT
dti-1548	294	19	thomas	thomas	PROPN
dti-1548	294	20	dl	dl	PROPN
dti-1548	294	21	.	.	PROPN
dti-1548	294	22	genetic	genetic	ADJ
dti-1548	294	23	epidemiology	epidemiology	NOUN
dti-1548	294	24	of	of	ADP
dti-1548	294	25	hepatitis	hepatitis	PROPN
dti-1548	294	26	c	c	PROPN
dti-1548	294	27	virus	virus	PROPN
dti-1548	294	28	throughout	throughout	ADP
dti-1548	294	29	egypt	egypt	PROPN
dti-1548	294	30	.	.	PUNCT
dti-1548	295	1	j	j	PROPN
dti-1548	295	2	infect	infect	VERB
dti-1548	295	3	dis	dis	PROPN
dti-1548	295	4	.	.	PUNCT
dti-1548	296	1	2000;182(3):698–707	2000;182(3):698–707	NUM
dti-1548	296	2	.	.	PUNCT
dti-1548	297	1	7	7	NUM
dti-1548	297	2	.	.	PUNCT
dti-1548	298	1	wang	wang	PROPN
dti-1548	298	2	y	y	PROPN
dti-1548	298	3	,	,	PUNCT
dti-1548	298	4	sun	sun	PROPN
dti-1548	298	5	y.	y.	PROPN
dti-1548	298	6	insulin	insulin	PROPN
dti-1548	298	7	-	-	PUNCT
dti-1548	298	8	like	like	ADJ
dti-1548	298	9	growth	growth	NOUN
dti-1548	298	10	factor	factor	NOUN
dti-1548	298	11	receptor-1	receptor-1	VERB
dti-1548	298	12	as	as	ADP
dti-1548	298	13	an	an	DET
dti-1548	298	14	anticancer	anticancer	NOUN
dti-1548	298	15	target	target	NOUN
dti-1548	298	16	:	:	PUNCT
dti-1548	298	17	blocking	block	VERB
dti-1548	298	18	transformation	transformation	NOUN
dti-1548	298	19	and	and	CCONJ
dti-1548	298	20	inducing	induce	VERB
dti-1548	298	21	apoptosis	apoptosis	NOUN
dti-1548	298	22	.	.	PUNCT
dti-1548	299	1	curr	curr	PROPN
dti-1548	299	2	cancer	cancer	NOUN
dti-1548	299	3	drug	drug	NOUN
dti-1548	299	4	targets	target	NOUN
dti-1548	299	5	.	.	PUNCT
dti-1548	300	1	2002;2(3):191–207	2002;2(3):191–207	NUM
dti-1548	300	2	.	.	X
dti-1548	300	3	8	8	NUM
dti-1548	300	4	.	.	PUNCT
dti-1548	300	5	christopoulos	christopoulos	PROPN
dti-1548	300	6	pf	pf	PROPN
dti-1548	300	7	,	,	PUNCT
dti-1548	300	8	msaouel	msaouel	NOUN
dti-1548	300	9	p	p	NOUN
dti-1548	300	10	,	,	PUNCT
dti-1548	300	11	koutsilieris	koutsilieris	PROPN
dti-1548	300	12	m.	m.	NOUN
dti-1548	300	13	the	the	DET
dti-1548	300	14	role	role	NOUN
dti-1548	300	15	of	of	ADP
dti-1548	300	16	the	the	DET
dti-1548	300	17	insulin	insulin	NOUN
dti-1548	300	18	-	-	PUNCT
dti-1548	300	19	like	like	ADJ
dti-1548	300	20	growth	growth	NOUN
dti-1548	300	21	factor-1	factor-1	NOUN
dti-1548	300	22	system	system	NOUN
dti-1548	300	23	in	in	ADP
dti-1548	300	24	breast	breast	NOUN
dti-1548	300	25	cancer	cancer	NOUN
dti-1548	300	26	.	.	PUNCT
dti-1548	301	1	mol	mol	ADP
dti-1548	301	2	cancer	cancer	NOUN
dti-1548	301	3	.	.	PUNCT
dti-1548	302	1	2015;14(1):43	2015;14(1):43	NUM
dti-1548	302	2	.	.	PUNCT
dti-1548	303	1	9	9	NUM
dti-1548	303	2	.	.	X
dti-1548	303	3	papa	papa	PROPN
dti-1548	303	4	v	v	PROPN
dti-1548	303	5	,	,	PUNCT
dti-1548	303	6	gliozzo	gliozzo	PROPN
dti-1548	303	7	b	b	PROPN
dti-1548	303	8	,	,	PUNCT
dti-1548	303	9	clark	clark	PROPN
dti-1548	303	10	gm	gm	PROPN
dti-1548	303	11	,	,	PUNCT
dti-1548	303	12	et	et	PROPN
dti-1548	303	13	al	al	PROPN
dti-1548	303	14	.	.	PUNCT
dti-1548	304	1	insulin	insulin	NOUN
dti-1548	304	2	-	-	PUNCT
dti-1548	304	3	like	like	ADJ
dti-1548	304	4	growth	growth	NOUN
dti-1548	304	5	factor	factor	NOUN
dti-1548	304	6	-	-	PUNCT
dti-1548	304	7	i	i	PRON
dti-1548	304	8	receptors	receptor	NOUN
dti-1548	304	9	are	be	AUX
dti-1548	304	10	overexpressed	overexpresse	VERB
dti-1548	304	11	and	and	CCONJ
dti-1548	304	12	predict	predict	VERB
dti-1548	304	13	a	a	DET
dti-1548	304	14	low	low	ADJ
dti-1548	304	15	risk	risk	NOUN
dti-1548	304	16	in	in	ADP
dti-1548	304	17	human	human	ADJ
dti-1548	304	18	breast	breast	NOUN
dti-1548	304	19	cancer	cancer	NOUN
dti-1548	304	20	.	.	PUNCT
dti-1548	305	1	cancer	cancer	NOUN
dti-1548	305	2	res	re	NOUN
dti-1548	305	3	.	.	PUNCT
dti-1548	306	1	1993;53(16):3736–3740	1993;53(16):3736–3740	NUM
dti-1548	306	2	.	.	PROPN
dti-1548	307	1	10	10	NUM
dti-1548	307	2	.	.	PUNCT
dti-1548	308	1	jones	jones	PROPN
dti-1548	308	2	r	r	PROPN
dti-1548	308	3	,	,	PUNCT
dti-1548	308	4	campbell	campbell	PROPN
dti-1548	308	5	c	c	PROPN
dti-1548	308	6	,	,	PUNCT
dti-1548	308	7	gunther	gunther	PROPN
dti-1548	308	8	e	e	PROPN
dti-1548	308	9	,	,	PUNCT
dti-1548	308	10	et	et	PROPN
dti-1548	308	11	al	al	PROPN
dti-1548	308	12	.	.	PUNCT
dti-1548	309	1	transgenic	transgenic	NOUN
dti-1548	309	2	overexpression	overexpression	NOUN
dti-1548	309	3	of	of	ADP
dti-1548	309	4	igf	igf	PROPN
dti-1548	309	5	-	-	ADJ
dti-1548	309	6	ir	ir	PROPN
dti-1548	309	7	disrupts	disrupt	VERB
dti-1548	309	8	mammary	mammary	ADJ
dti-1548	309	9	ductal	ductal	ADJ
dti-1548	309	10	morphogenesis	morphogenesis	NOUN
dti-1548	309	11	and	and	CCONJ
dti-1548	309	12	induces	induce	VERB
dti-1548	309	13	tumor	tumor	NOUN
dti-1548	309	14	formation	formation	NOUN
dti-1548	309	15	.	.	PUNCT
dti-1548	310	1	oncogene	oncogene	NOUN
dti-1548	310	2	.	.	PUNCT
dti-1548	311	1	2007;26(11):1636–1644	2007;26(11):1636–1644	NUM
dti-1548	311	2	.	.	NOUN
dti-1548	311	3	11	11	NUM
dti-1548	311	4	.	.	PUNCT
dti-1548	312	1	samani	samani	PROPN
dti-1548	312	2	aa	aa	PROPN
dti-1548	312	3	,	,	PUNCT
dti-1548	312	4	yakar	yakar	NOUN
dti-1548	312	5	s	s	NOUN
dti-1548	312	6	,	,	PUNCT
dti-1548	312	7	leroith	leroith	NOUN
dti-1548	312	8	d	d	NOUN
dti-1548	312	9	,	,	PUNCT
dti-1548	312	10	brodt	brodt	PROPN
dti-1548	312	11	p.	p.	NOUN
dti-1548	312	12	the	the	DET
dti-1548	312	13	role	role	NOUN
dti-1548	312	14	of	of	ADP
dti-1548	312	15	the	the	DET
dti-1548	312	16	igf	igf	PROPN
dti-1548	312	17	system	system	NOUN
dti-1548	312	18	in	in	ADP
dti-1548	312	19	cancer	cancer	NOUN
dti-1548	312	20	growth	growth	NOUN
dti-1548	312	21	and	and	CCONJ
dti-1548	312	22	metastasis	metastasis	NOUN
dti-1548	312	23	:	:	PUNCT
dti-1548	312	24	overview	overview	NOUN
dti-1548	312	25	and	and	CCONJ
dti-1548	312	26	recent	recent	ADJ
dti-1548	312	27	insights	insight	NOUN
dti-1548	312	28	.	.	PUNCT
dti-1548	313	1	endocr	endocr	PROPN
dti-1548	313	2	rev	rev	PROPN
dti-1548	313	3	.	.	PROPN
dti-1548	313	4	2007;28(1):20–47	2007;28(1):20–47	PROPN
dti-1548	313	5	.	.	PUNCT
dti-1548	314	1	possible	possible	ADJ
dti-1548	314	2	therapeutic	therapeutic	ADJ
dti-1548	314	3	targets	target	NOUN
dti-1548	314	4	in	in	ADP
dti-1548	314	5	igf1r	igf1r	ADJ
dti-1548	314	6	pathway	pathway	NOUN
dti-1548	314	7	in	in	ADP
dti-1548	314	8	egyptian	egyptian	ADJ
dti-1548	314	9	hcv	hcv	X
dti-1548	314	10	related	relate	VERB
dti-1548	314	11	hcc10	hcc10	NOUN
dti-1548	314	12	©	©	PROPN
dti-1548	314	13	2020	2020	NUM
dti-1548	314	14	the	the	DET
dti-1548	314	15	authors	author	NOUN
dti-1548	314	16	.	.	PUNCT
dti-1548	315	1	published	publish	VERB
dti-1548	315	2	by	by	ADP
dti-1548	315	3	aboutscience	aboutscience	NOUN
dti-1548	315	4	12	12	NUM
dti-1548	315	5	.	.	PUNCT
dti-1548	316	1	vescovo	vescovo	PROPN
dti-1548	316	2	t	t	PROPN
dti-1548	316	3	,	,	PUNCT
dti-1548	316	4	refolo	refolo	NOUN
dti-1548	316	5	g	g	PROPN
dti-1548	316	6	,	,	PUNCT
dti-1548	316	7	vitagliano	vitagliano	PROPN
dti-1548	316	8	g	g	NOUN
dti-1548	316	9	,	,	PUNCT
dti-1548	316	10	fimia	fimia	ADJ
dti-1548	316	11	gm	gm	PROPN
dti-1548	316	12	,	,	PUNCT
dti-1548	316	13	piacentini	piacentini	VERB
dti-1548	316	14	m.	m.	NOUN
dti-1548	316	15	molecular	molecular	ADJ
dti-1548	316	16	mechanisms	mechanism	NOUN
dti-1548	316	17	of	of	ADP
dti-1548	316	18	hepatitis	hepatitis	PROPN
dti-1548	316	19	c	c	PROPN
dti-1548	316	20	virus	virus	NOUN
dti-1548	316	21	–	–	PUNCT
dti-1548	316	22	induced	induce	VERB
dti-1548	316	23	hepatocellular	hepatocellular	ADJ
dti-1548	316	24	carcinoma	carcinoma	NOUN
dti-1548	316	25	.	.	PUNCT
dti-1548	317	1	clin	clin	PROPN
dti-1548	317	2	microbiol	microbiol	PROPN
dti-1548	317	3	infect	infect	PROPN
dti-1548	317	4	.	.	PUNCT
dti-1548	318	1	2016;22(10):853–861	2016;22(10):853–861	NUM
dti-1548	318	2	.	.	PUNCT
dti-1548	319	1	13	13	NUM
dti-1548	319	2	.	.	X
dti-1548	320	1	patel	patel	PROPN
dti-1548	320	2	a	a	PRON
dti-1548	320	3	,	,	PUNCT
dti-1548	320	4	sun	sun	PROPN
dti-1548	320	5	w.	w.	PROPN
dti-1548	320	6	molecular	molecular	ADJ
dti-1548	320	7	targeted	target	VERB
dti-1548	320	8	therapy	therapy	NOUN
dti-1548	320	9	in	in	ADP
dti-1548	320	10	hepatocellular	hepatocellular	ADJ
dti-1548	320	11	carcinoma	carcinoma	NOUN
dti-1548	320	12	:	:	PUNCT
dti-1548	320	13	from	from	ADP
dti-1548	320	14	biology	biology	NOUN
dti-1548	320	15	to	to	ADP
dti-1548	320	16	clinical	clinical	ADJ
dti-1548	320	17	practice	practice	NOUN
dti-1548	320	18	and	and	CCONJ
dti-1548	320	19	future	future	NOUN
dti-1548	320	20	.	.	PUNCT
dti-1548	321	1	curr	curr	PROPN
dti-1548	321	2	treat	treat	VERB
dti-1548	321	3	opt	opt	PROPN
dti-1548	321	4	oncol	oncol	ADJ
dti-1548	321	5	.	.	PUNCT
dti-1548	322	1	2014;15(3):380–394	2014;15(3):380–394	NUM
dti-1548	322	2	.	.	NOUN
dti-1548	322	3	14	14	NUM
dti-1548	322	4	.	.	PUNCT
dti-1548	323	1	lu	lu	PROPN
dti-1548	324	1	l	l	NOUN
dti-1548	324	2	-	-	PUNCT
dti-1548	324	3	c	c	PROPN
dti-1548	324	4	,	,	PUNCT
dti-1548	324	5	hsu	hsu	PROPN
dti-1548	324	6	c	c	PROPN
dti-1548	324	7	-	-	PUNCT
dti-1548	324	8	h	h	PROPN
dti-1548	324	9	,	,	PUNCT
dti-1548	324	10	hsu	hsu	PROPN
dti-1548	324	11	c	c	PROPN
dti-1548	324	12	,	,	PUNCT
dti-1548	324	13	cheng	cheng	PROPN
dti-1548	324	14	a	a	PROPN
dti-1548	324	15	-	-	PUNCT
dti-1548	324	16	l.	l.	NOUN
dti-1548	324	17	tumor	tumor	NOUN
dti-1548	324	18	heterogeneity	heterogeneity	NOUN
dti-1548	324	19	in	in	ADP
dti-1548	324	20	hepatocellular	hepatocellular	ADJ
dti-1548	324	21	carcinoma	carcinoma	NOUN
dti-1548	324	22	:	:	PUNCT
dti-1548	324	23	facing	face	VERB
dti-1548	324	24	the	the	DET
dti-1548	324	25	challenges	challenge	NOUN
dti-1548	324	26	.	.	PUNCT
dti-1548	325	1	liver	liver	NOUN
dti-1548	325	2	cancer	cancer	NOUN
dti-1548	325	3	.	.	PUNCT
dti-1548	326	1	2016;5(2):128–138	2016;5(2):128–138	NUM
dti-1548	326	2	.	.	PUNCT
dti-1548	326	3	15	15	NUM
dti-1548	326	4	.	.	PUNCT
dti-1548	326	5	luo	luo	PROPN
dti-1548	326	6	jh	jh	PROPN
dti-1548	326	7	,	,	PUNCT
dti-1548	326	8	ren	ren	PROPN
dti-1548	326	9	b	b	PROPN
dti-1548	326	10	,	,	PUNCT
dti-1548	326	11	keryanov	keryanov	PROPN
dti-1548	326	12	s	s	PROPN
dti-1548	326	13	,	,	PUNCT
dti-1548	326	14	et	et	PROPN
dti-1548	326	15	al	al	PROPN
dti-1548	326	16	.	.	PROPN
dti-1548	326	17	transcriptomic	transcriptomic	ADJ
dti-1548	326	18	and	and	CCONJ
dti-1548	326	19	genomic	genomic	ADJ
dti-1548	326	20	analysis	analysis	NOUN
dti-1548	326	21	of	of	ADP
dti-1548	326	22	human	human	ADJ
dti-1548	326	23	hepatocellular	hepatocellular	ADJ
dti-1548	326	24	carcinomas	carcinoma	NOUN
dti-1548	326	25	and	and	CCONJ
dti-1548	326	26	hepatoblastomas	hepatoblastoma	NOUN
dti-1548	326	27	.	.	PUNCT
dti-1548	327	1	hepatology	hepatology	PROPN
dti-1548	327	2	.	.	PUNCT
dti-1548	328	1	2006;44(4):1012–1024	2006;44(4):1012–1024	NUM
dti-1548	328	2	.	.	PUNCT
dti-1548	329	1	16	16	NUM
dti-1548	329	2	.	.	PUNCT
dti-1548	330	1	lee	lee	PROPN
dti-1548	330	2	js	js	PROPN
dti-1548	330	3	,	,	PUNCT
dti-1548	330	4	chu	chu	PROPN
dti-1548	330	5	is	be	AUX
dti-1548	330	6	,	,	PUNCT
dti-1548	330	7	heo	heo	PROPN
dti-1548	330	8	j	j	PROPN
dti-1548	330	9	,	,	PUNCT
dti-1548	330	10	et	et	PROPN
dti-1548	330	11	al	al	PROPN
dti-1548	330	12	.	.	PUNCT
dti-1548	330	13	classification	classification	NOUN
dti-1548	330	14	and	and	CCONJ
dti-1548	330	15	prediction	prediction	NOUN
dti-1548	330	16	of	of	ADP
dti-1548	330	17	survival	survival	NOUN
dti-1548	330	18	in	in	ADP
dti-1548	330	19	hepatocellular	hepatocellular	ADJ
dti-1548	330	20	carcinoma	carcinoma	NOUN
dti-1548	330	21	by	by	ADP
dti-1548	330	22	gene	gene	NOUN
dti-1548	330	23	expression	expression	NOUN
dti-1548	330	24	profiling	profiling	NOUN
dti-1548	330	25	.	.	PUNCT
dti-1548	331	1	hepatology	hepatology	NOUN
dti-1548	331	2	.	.	PUNCT
dti-1548	332	1	2004;40(3):667–676	2004;40(3):667–676	NUM
dti-1548	332	2	.	.	PROPN
dti-1548	332	3	17	17	NUM
dti-1548	332	4	.	.	PUNCT
dti-1548	332	5	shirota	shirota	NOUN
dti-1548	332	6	y	y	PROPN
dti-1548	332	7	,	,	PUNCT
dti-1548	332	8	kaneko	kaneko	PROPN
dti-1548	332	9	s	s	PROPN
dti-1548	332	10	,	,	PUNCT
dti-1548	332	11	honda	honda	PROPN
dti-1548	332	12	m	m	PROPN
dti-1548	332	13	,	,	PUNCT
dti-1548	332	14	kawai	kawai	PROPN
dti-1548	332	15	hf	hf	PROPN
dti-1548	332	16	,	,	PUNCT
dti-1548	332	17	kobayashi	kobayashi	PROPN
dti-1548	332	18	k.	k.	PROPN
dti-1548	332	19	identification	identification	NOUN
dti-1548	332	20	of	of	ADP
dti-1548	332	21	differentially	differentially	ADV
dti-1548	332	22	expressed	express	VERB
dti-1548	332	23	genes	gene	NOUN
dti-1548	332	24	in	in	ADP
dti-1548	332	25	hepatocellular	hepatocellular	ADJ
dti-1548	332	26	carcinoma	carcinoma	NOUN
dti-1548	332	27	with	with	ADP
dti-1548	332	28	cdna	cdna	PROPN
dti-1548	332	29	microarrays	microarray	NOUN
dti-1548	332	30	.	.	PUNCT
dti-1548	333	1	hepatology	hepatology	NOUN
dti-1548	333	2	.	.	PUNCT
dti-1548	334	1	2001;33(4	2001;33(4	NUM
dti-1548	334	2	):	):	PUNCT
dti-1548	334	3	832–840	832–840	NUM
dti-1548	334	4	.	.	PUNCT
dti-1548	335	1	18	18	NUM
dti-1548	335	2	.	.	PUNCT
dti-1548	335	3	tackels	tackel	NOUN
dti-1548	335	4	-	-	PUNCT
dti-1548	335	5	horne	horne	PROPN
dti-1548	335	6	d	d	PROPN
dti-1548	335	7	,	,	PUNCT
dti-1548	335	8	goodman	goodman	PROPN
dti-1548	335	9	md	md	PROPN
dti-1548	335	10	,	,	PUNCT
dti-1548	335	11	williams	williams	PROPN
dti-1548	335	12	aj	aj	PROPN
dti-1548	335	13	,	,	PUNCT
dti-1548	335	14	et	et	PROPN
dti-1548	335	15	al	al	PROPN
dti-1548	335	16	.	.	PUNCT
dti-1548	336	1	identification	identification	NOUN
dti-1548	336	2	of	of	ADP
dti-1548	336	3	differentially	differentially	ADV
dti-1548	336	4	expressed	express	VERB
dti-1548	336	5	genes	gene	NOUN
dti-1548	336	6	in	in	ADP
dti-1548	336	7	hepatocellular	hepatocellular	ADJ
dti-1548	336	8	carcinoma	carcinoma	NOUN
dti-1548	336	9	and	and	CCONJ
dti-1548	336	10	metastatic	metastatic	ADJ
dti-1548	336	11	liver	liver	NOUN
dti-1548	336	12	tumors	tumor	NOUN
dti-1548	336	13	by	by	ADP
dti-1548	336	14	oligonucleotide	oligonucleotide	ADJ
dti-1548	336	15	expression	expression	NOUN
dti-1548	336	16	profiling	profiling	NOUN
dti-1548	336	17	.	.	PUNCT
dti-1548	337	1	cancer	cancer	NOUN
dti-1548	337	2	.	.	PUNCT
dti-1548	338	1	2001;92(2):395–405	2001;92(2):395–405	X
dti-1548	338	2	.	.	X
dti-1548	338	3	19	19	NUM
dti-1548	338	4	.	.	PUNCT
dti-1548	338	5	patil	patil	PROPN
dti-1548	338	6	ma	ma	PROPN
dti-1548	338	7	,	,	PUNCT
dti-1548	338	8	chua	chua	PROPN
dti-1548	338	9	m	m	PROPN
dti-1548	338	10	-	-	PUNCT
dti-1548	338	11	s	s	PROPN
dti-1548	338	12	,	,	PUNCT
dti-1548	338	13	pan	pan	ADJ
dti-1548	338	14	k	k	PROPN
dti-1548	338	15	-	-	PROPN
dti-1548	338	16	h	h	PROPN
dti-1548	338	17	,	,	PUNCT
dti-1548	338	18	et	et	PROPN
dti-1548	338	19	al	al	PROPN
dti-1548	338	20	.	.	PUNCT
dti-1548	339	1	an	an	DET
dti-1548	339	2	integrated	integrate	VERB
dti-1548	339	3	data	data	NOUN
dti-1548	339	4	analysis	analysis	NOUN
dti-1548	339	5	approach	approach	NOUN
dti-1548	339	6	to	to	PART
dti-1548	339	7	characterize	characterize	VERB
dti-1548	339	8	genes	gene	NOUN
dti-1548	339	9	highly	highly	ADV
dti-1548	339	10	expressed	express	VERB
dti-1548	339	11	in	in	ADP
dti-1548	339	12	hepatocellular	hepatocellular	ADJ
dti-1548	339	13	carcinoma	carcinoma	NOUN
dti-1548	339	14	.	.	PUNCT
dti-1548	340	1	oncogene	oncogene	NOUN
dti-1548	340	2	.	.	PUNCT
dti-1548	341	1	2005;24(23):3737–3747	2005;24(23):3737–3747	X
dti-1548	341	2	.	.	PROPN
dti-1548	342	1	20	20	NUM
dti-1548	342	2	.	.	PUNCT
dti-1548	343	1	guimei	guimei	PROPN
dti-1548	343	2	m	m	PROPN
dti-1548	343	3	,	,	PUNCT
dti-1548	343	4	baddour	baddour	PROPN
dti-1548	343	5	n	n	SYM
dti-1548	343	6	,	,	PUNCT
dti-1548	343	7	elkaffash	elkaffash	NOUN
dti-1548	343	8	d	d	NOUN
dti-1548	343	9	,	,	PUNCT
dti-1548	343	10	abdou	abdou	PROPN
dti-1548	343	11	l	l	PROPN
dti-1548	343	12	,	,	PUNCT
dti-1548	343	13	taher	taher	PROPN
dti-1548	343	14	y.	y.	PROPN
dti-1548	343	15	gremlin	gremlin	PROPN
dti-1548	343	16	in	in	ADP
dti-1548	343	17	the	the	DET
dti-1548	343	18	pathogenesis	pathogenesis	NOUN
dti-1548	343	19	of	of	ADP
dti-1548	343	20	hepatocellular	hepatocellular	ADJ
dti-1548	343	21	carcinoma	carcinoma	NOUN
dti-1548	343	22	complicating	complicate	VERB
dti-1548	343	23	chronic	chronic	ADJ
dti-1548	343	24	hepatitis	hepatitis	NOUN
dti-1548	343	25	c	c	NOUN
dti-1548	343	26	:	:	PUNCT
dti-1548	343	27	an	an	DET
dti-1548	343	28	immunohistochemical	immunohistochemical	ADJ
dti-1548	343	29	and	and	CCONJ
dti-1548	343	30	pcr	pcr	ADJ
dti-1548	343	31	study	study	NOUN
dti-1548	343	32	of	of	ADP
dti-1548	343	33	human	human	ADJ
dti-1548	343	34	liver	liver	NOUN
dti-1548	343	35	biopsies	biopsy	NOUN
dti-1548	343	36	.	.	PUNCT
dti-1548	344	1	bmc	bmc	ADJ
dti-1548	344	2	res	re	NOUN
dti-1548	344	3	notes	note	NOUN
dti-1548	344	4	.	.	PUNCT
dti-1548	345	1	2012;5(1):390	2012;5(1):390	X
dti-1548	345	2	.	.	PUNCT
dti-1548	346	1	21	21	NUM
dti-1548	346	2	.	.	PUNCT
dti-1548	347	1	huynh	huynh	PROPN
dti-1548	347	2	h.	h.	PROPN
dti-1548	347	3	molecularly	molecularly	ADV
dti-1548	347	4	targeted	target	VERB
dti-1548	347	5	therapy	therapy	NOUN
dti-1548	347	6	in	in	ADP
dti-1548	347	7	hepatocellular	hepatocellular	ADJ
dti-1548	347	8	carcinoma	carcinoma	NOUN
dti-1548	347	9	.	.	PUNCT
dti-1548	348	1	biochem	biochem	PROPN
dti-1548	348	2	pharmacol	pharmacol	PROPN
dti-1548	348	3	.	.	PUNCT
dti-1548	349	1	2010;80(5):550–560	2010;80(5):550–560	NUM
dti-1548	349	2	.	.	X
dti-1548	350	1	22	22	NUM
dti-1548	350	2	.	.	PUNCT
dti-1548	351	1	saez	saez	PROPN
dti-1548	351	2	e	e	PROPN
dti-1548	351	3	,	,	PUNCT
dti-1548	351	4	rutberg	rutberg	PROPN
dti-1548	351	5	se	se	PROPN
dti-1548	351	6	,	,	PUNCT
dti-1548	351	7	mueller	mueller	PROPN
dti-1548	351	8	e	e	PROPN
dti-1548	351	9	,	,	PUNCT
dti-1548	351	10	et	et	PROPN
dti-1548	351	11	al	al	PROPN
dti-1548	351	12	.	.	PUNCT
dti-1548	352	1	c	c	X
dti-1548	352	2	-	-	PUNCT
dti-1548	352	3	fos	fos	NOUN
dti-1548	352	4	is	be	AUX
dti-1548	352	5	required	require	VERB
dti-1548	352	6	for	for	ADP
dti-1548	352	7	malignant	malignant	ADJ
dti-1548	352	8	progression	progression	NOUN
dti-1548	352	9	of	of	ADP
dti-1548	352	10	skin	skin	NOUN
dti-1548	352	11	tumors	tumor	NOUN
dti-1548	352	12	.	.	PUNCT
dti-1548	353	1	cell	cell	NOUN
dti-1548	353	2	.	.	PUNCT
dti-1548	354	1	1995;82(5):721–732	1995;82(5):721–732	X
dti-1548	354	2	.	.	X
dti-1548	354	3	23	23	NUM
dti-1548	354	4	.	.	PUNCT
dti-1548	355	1	yuen	yuen	PROPN
dti-1548	355	2	mf	mf	PROPN
dti-1548	355	3	,	,	PUNCT
dti-1548	355	4	wu	wu	PROPN
dti-1548	355	5	pc	pc	PROPN
dti-1548	355	6	,	,	PUNCT
dti-1548	355	7	lai	lai	PROPN
dti-1548	355	8	vch	vch	PROPN
dti-1548	355	9	,	,	PUNCT
dti-1548	355	10	lau	lau	PROPN
dti-1548	355	11	jyn	jyn	PROPN
dti-1548	355	12	,	,	PUNCT
dti-1548	355	13	lai	lai	PROPN
dti-1548	355	14	cl	cl	NOUN
dti-1548	355	15	.	.	PUNCT
dti-1548	356	1	expression	expression	NOUN
dti-1548	356	2	of	of	ADP
dti-1548	356	3	c	c	NOUN
dti-1548	356	4	-	-	PUNCT
dti-1548	356	5	myc	myc	NOUN
dti-1548	356	6	,	,	PUNCT
dti-1548	356	7	c	c	NOUN
dti-1548	356	8	-	-	PUNCT
dti-1548	356	9	fos	fos	NOUN
dti-1548	356	10	,	,	PUNCT
dti-1548	356	11	and	and	CCONJ
dti-1548	356	12	c	c	X
dti-1548	356	13	-	-	PUNCT
dti-1548	356	14	jun	jun	PROPN
dti-1548	356	15	in	in	ADP
dti-1548	356	16	hepatocellular	hepatocellular	ADJ
dti-1548	356	17	carcinoma	carcinoma	NOUN
dti-1548	356	18	.	.	PUNCT
dti-1548	357	1	cancer	cancer	NOUN
dti-1548	357	2	.	.	PUNCT
dti-1548	358	1	2001	2001	NUM
dti-1548	358	2	;	;	PUNCT
dti-1548	359	1	91(1):106–112	91(1):106–112	X
dti-1548	359	2	.	.	PUNCT
dti-1548	360	1	24	24	NUM
dti-1548	360	2	.	.	PUNCT
dti-1548	361	1	kamide	kamide	PROPN
dti-1548	361	2	d	d	PROPN
dti-1548	361	3	,	,	PUNCT
dti-1548	361	4	yamashita	yamashita	PROPN
dti-1548	361	5	t	t	PROPN
dti-1548	361	6	,	,	PUNCT
dti-1548	361	7	araki	araki	PROPN
dti-1548	361	8	k	k	PROPN
dti-1548	361	9	,	,	PUNCT
dti-1548	361	10	et	et	PROPN
dti-1548	361	11	al	al	PROPN
dti-1548	361	12	.	.	PROPN
dti-1548	361	13	selective	selective	ADJ
dti-1548	361	14	activator	activator	NOUN
dti-1548	361	15	protein-1	protein-1	NUM
dti-1548	361	16	inhibitor	inhibitor	NOUN
dti-1548	361	17	t-5224	t-5224	PROPN
dti-1548	361	18	prevents	prevent	VERB
dti-1548	361	19	lymph	lymph	NOUN
dti-1548	361	20	node	node	NOUN
dti-1548	361	21	metastasis	metastasis	NOUN
dti-1548	361	22	in	in	ADP
dti-1548	361	23	an	an	DET
dti-1548	361	24	oral	oral	ADJ
dti-1548	361	25	cancer	cancer	NOUN
dti-1548	361	26	model	model	NOUN
dti-1548	361	27	.	.	PUNCT
dti-1548	362	1	cancer	cancer	PROPN
dti-1548	362	2	sci	sci	PROPN
dti-1548	362	3	.	.	PUNCT
dti-1548	363	1	2016;107(5):666–673	2016;107(5):666–673	NUM
dti-1548	363	2	.	.	PUNCT
dti-1548	364	1	25	25	NUM
dti-1548	364	2	.	.	PUNCT
dti-1548	365	1	wang	wang	PROPN
dti-1548	365	2	l	l	PROPN
dti-1548	365	3	,	,	PUNCT
dti-1548	365	4	yao	yao	PROPN
dti-1548	365	5	j	j	PROPN
dti-1548	365	6	,	,	PUNCT
dti-1548	365	7	zhang	zhang	PROPN
dti-1548	365	8	x	x	PROPN
dti-1548	365	9	,	,	PUNCT
dti-1548	365	10	et	et	PROPN
dti-1548	365	11	al	al	PROPN
dti-1548	365	12	.	.	PUNCT
dti-1548	366	1	mirna-302b	mirna-302b	PROPN
dti-1548	366	2	suppresses	suppress	VERB
dti-1548	366	3	human	human	ADJ
dti-1548	366	4	hepatocellular	hepatocellular	ADJ
dti-1548	366	5	carcinoma	carcinoma	NOUN
dti-1548	366	6	by	by	ADP
dti-1548	366	7	targeting	target	VERB
dti-1548	366	8	akt2	akt2	PROPN
dti-1548	366	9	.	.	PUNCT
dti-1548	367	1	mol	mol	ADP
dti-1548	367	2	cancer	cancer	NOUN
dti-1548	367	3	res	re	NOUN
dti-1548	367	4	.	.	PUNCT
dti-1548	368	1	2014;12(2):190–202	2014;12(2):190–202	NUM
dti-1548	368	2	.	.	NOUN
dti-1548	368	3	26	26	NUM
dti-1548	368	4	.	.	PUNCT
dti-1548	369	1	zhang	zhang	PROPN
dti-1548	369	2	y	y	PROPN
dti-1548	369	3	,	,	PUNCT
dti-1548	369	4	guo	guo	PROPN
dti-1548	369	5	x	x	PROPN
dti-1548	369	6	,	,	PUNCT
dti-1548	369	7	yang	yang	PROPN
dti-1548	369	8	m	m	PROPN
dti-1548	369	9	,	,	PUNCT
dti-1548	369	10	yu	yu	PROPN
dti-1548	369	11	l	l	PROPN
dti-1548	369	12	,	,	PUNCT
dti-1548	369	13	li	li	PROPN
dti-1548	369	14	z	z	PROPN
dti-1548	369	15	,	,	PUNCT
dti-1548	369	16	lin	lin	PROPN
dti-1548	369	17	n.	n.	PROPN
dti-1548	369	18	identification	identification	NOUN
dti-1548	369	19	of	of	ADP
dti-1548	369	20	akt	akt	PROPN
dti-1548	369	21	kinases	kinase	NOUN
dti-1548	369	22	as	as	ADP
dti-1548	369	23	unfavorable	unfavorable	ADJ
dti-1548	369	24	prognostic	prognostic	ADJ
dti-1548	369	25	factors	factor	NOUN
dti-1548	369	26	for	for	ADP
dti-1548	369	27	hepatocellular	hepatocellular	ADJ
dti-1548	369	28	carcinoma	carcinoma	NOUN
dti-1548	369	29	by	by	ADP
dti-1548	369	30	a	a	DET
dti-1548	369	31	combination	combination	NOUN
dti-1548	369	32	of	of	ADP
dti-1548	369	33	expression	expression	NOUN
dti-1548	369	34	profile	profile	NOUN
dti-1548	369	35	,	,	PUNCT
dti-1548	369	36	interaction	interaction	NOUN
dti-1548	369	37	network	network	NOUN
dti-1548	369	38	analysis	analysis	NOUN
dti-1548	369	39	and	and	CCONJ
dti-1548	369	40	clinical	clinical	ADJ
dti-1548	369	41	validation	validation	NOUN
dti-1548	369	42	.	.	PUNCT
dti-1548	370	1	mol	mol	ADP
dti-1548	370	2	biosyst	biosyst	NOUN
dti-1548	370	3	.	.	PUNCT
dti-1548	371	1	2014;10(2):215–222	2014;10(2):215–222	NUM
dti-1548	371	2	.	.	NOUN
dti-1548	371	3	27	27	NUM
dti-1548	371	4	.	.	PUNCT
dti-1548	372	1	kurokawa	kurokawa	PROPN
dti-1548	372	2	y	y	PROPN
dti-1548	372	3	,	,	PUNCT
dti-1548	372	4	matoba	matoba	NOUN
dti-1548	372	5	r	r	NOUN
dti-1548	372	6	,	,	PUNCT
dti-1548	372	7	takemasa	takemasa	PROPN
dti-1548	372	8	i	i	PRON
dti-1548	372	9	,	,	PUNCT
dti-1548	372	10	et	et	PROPN
dti-1548	372	11	al	al	PROPN
dti-1548	372	12	.	.	PUNCT
dti-1548	373	1	molecular	molecular	ADJ
dti-1548	373	2	features	feature	NOUN
dti-1548	373	3	of	of	ADP
dti-1548	373	4	non	non	ADJ
dti-1548	373	5	-	-	ADJ
dti-1548	373	6	b	b	ADJ
dti-1548	373	7	,	,	PUNCT
dti-1548	373	8	non	non	ADJ
dti-1548	373	9	-	-	ADJ
dti-1548	373	10	c	c	ADJ
dti-1548	373	11	hepatocellular	hepatocellular	ADJ
dti-1548	373	12	carcinoma	carcinoma	NOUN
dti-1548	373	13	:	:	PUNCT
dti-1548	373	14	a	a	DET
dti-1548	373	15	pcr	pcr	NOUN
dti-1548	373	16	-	-	PUNCT
dti-1548	373	17	array	array	NOUN
dti-1548	373	18	gene	gene	NOUN
dti-1548	373	19	expression	expression	NOUN
dti-1548	373	20	profiling	profiling	NOUN
dti-1548	373	21	study	study	NOUN
dti-1548	373	22	.	.	PUNCT
dti-1548	374	1	j	j	PROPN
dti-1548	374	2	hepatol	hepatol	ADJ
dti-1548	374	3	.	.	PUNCT
dti-1548	375	1	2003;39(6):1004–1012	2003;39(6):1004–1012	NUM
dti-1548	375	2	.	.	PUNCT
dti-1548	376	1	28	28	NUM
dti-1548	376	2	.	.	PUNCT
dti-1548	377	1	huang	huang	PROPN
dti-1548	377	2	c	c	PROPN
dti-1548	377	3	-	-	PROPN
dti-1548	377	4	y	y	PROPN
dti-1548	377	5	,	,	PUNCT
dti-1548	377	6	huang	huang	PROPN
dti-1548	377	7	x	x	PROPN
dti-1548	377	8	-	-	PROPN
dti-1548	377	9	p	p	X
dti-1548	377	10	,	,	PUNCT
dti-1548	377	11	zhu	zhu	PROPN
dti-1548	377	12	j	j	PROPN
dti-1548	377	13	-	-	PROPN
dti-1548	377	14	y	y	PROPN
dti-1548	377	15	,	,	PUNCT
dti-1548	377	16	et	et	PROPN
dti-1548	377	17	al	al	PROPN
dti-1548	377	18	.	.	PROPN
dti-1548	377	19	mir-128	mir-128	NOUN
dti-1548	377	20	-	-	PUNCT
dti-1548	377	21	3p	3p	NOUN
dti-1548	377	22	suppresses	suppress	VERB
dti-1548	377	23	hepatocellular	hepatocellular	ADJ
dti-1548	377	24	carcinoma	carcinoma	NOUN
dti-1548	377	25	proliferation	proliferation	NOUN
dti-1548	377	26	by	by	ADP
dti-1548	377	27	regulating	regulate	VERB
dti-1548	377	28	pik3r1	pik3r1	NOUN
dti-1548	377	29	and	and	CCONJ
dti-1548	377	30	is	be	AUX
dti-1548	377	31	correlated	correlate	VERB
dti-1548	377	32	with	with	ADP
dti-1548	377	33	the	the	DET
dti-1548	377	34	prognosis	prognosis	NOUN
dti-1548	377	35	of	of	ADP
dti-1548	377	36	hcc	hcc	PROPN
dti-1548	377	37	patients	patient	NOUN
dti-1548	377	38	.	.	PUNCT
dti-1548	378	1	oncol	oncol	PROPN
dti-1548	378	2	rep	rep	PROPN
dti-1548	378	3	.	.	PROPN
dti-1548	378	4	2015;33(6):2889–2898	2015;33(6):2889–2898	PROPN
dti-1548	378	5	.	.	PUNCT
dti-1548	379	1	29	29	NUM
dti-1548	379	2	.	.	PUNCT
dti-1548	380	1	wang	wang	PROPN
dti-1548	380	2	jm	jm	PROPN
dti-1548	380	3	,	,	PUNCT
dti-1548	380	4	li	li	PROPN
dti-1548	380	5	q	q	AUX
dti-1548	380	6	,	,	PUNCT
dti-1548	380	7	du	du	PROPN
dti-1548	380	8	gs	gs	PROPN
dti-1548	380	9	,	,	PUNCT
dti-1548	380	10	lu	lu	PROPN
dti-1548	380	11	jx	jx	PROPN
dti-1548	380	12	,	,	PUNCT
dti-1548	380	13	zou	zou	PROPN
dti-1548	380	14	sq	sq	PROPN
dti-1548	380	15	.	.	PROPN
dti-1548	380	16	significance	significance	NOUN
dti-1548	380	17	and	and	CCONJ
dti-1548	380	18	expression	expression	NOUN
dti-1548	380	19	of	of	ADP
dti-1548	380	20	atypical	atypical	ADJ
dti-1548	380	21	protein	protein	NOUN
dti-1548	380	22	kinase	kinase	NOUN
dti-1548	380	23	c	c	NOUN
dti-1548	380	24	-	-	PUNCT
dti-1548	380	25	iota	iota	NOUN
dti-1548	380	26	in	in	ADP
dti-1548	380	27	human	human	ADJ
dti-1548	380	28	hepatocellular	hepatocellular	ADJ
dti-1548	380	29	carcinoma	carcinoma	NOUN
dti-1548	380	30	.	.	PUNCT
dti-1548	381	1	j	j	PROPN
dti-1548	381	2	surg	surg	PROPN
dti-1548	381	3	res	re	NOUN
dti-1548	381	4	.	.	PUNCT
dti-1548	382	1	2009;154(1):143–149	2009;154(1):143–149	NUM
dti-1548	382	2	.	.	NOUN
dti-1548	382	3	30	30	NUM
dti-1548	382	4	.	.	PUNCT
dti-1548	383	1	chen	chen	PROPN
dti-1548	383	2	x	x	PROPN
dti-1548	383	3	,	,	PUNCT
dti-1548	383	4	cheung	cheung	PROPN
dti-1548	383	5	st	st	PROPN
dti-1548	383	6	,	,	PUNCT
dti-1548	383	7	so	so	PROPN
dti-1548	383	8	s	s	PROPN
dti-1548	383	9	,	,	PUNCT
dti-1548	383	10	et	et	PROPN
dti-1548	383	11	al	al	PROPN
dti-1548	383	12	.	.	PUNCT
dti-1548	384	1	gene	gene	NOUN
dti-1548	384	2	expression	expression	NOUN
dti-1548	384	3	patterns	pattern	NOUN
dti-1548	384	4	in	in	ADP
dti-1548	384	5	human	human	ADJ
dti-1548	384	6	liver	liver	NOUN
dti-1548	384	7	cancers	cancer	NOUN
dti-1548	384	8	.	.	PUNCT
dti-1548	385	1	mol	mol	ADP
dti-1548	385	2	biol	biol	ADJ
dti-1548	385	3	cell	cell	NOUN
dti-1548	385	4	.	.	PUNCT
dti-1548	386	1	2002;13(6):1929–1939	2002;13(6):1929–1939	NUM
dti-1548	386	2	.	.	PUNCT
dti-1548	387	1	31	31	NUM
dti-1548	387	2	.	.	PUNCT
dti-1548	388	1	ro	ro	PROPN
dti-1548	388	2	h	h	PROPN
dti-1548	388	3	-	-	PUNCT
dti-1548	388	4	s	s	PROPN
dti-1548	388	5	,	,	PUNCT
dti-1548	388	6	roncari	roncari	PROPN
dti-1548	388	7	d.	d.	PROPN
dti-1548	388	8	the	the	DET
dti-1548	388	9	c	c	PROPN
dti-1548	388	10	/	/	SYM
dti-1548	388	11	ebp	ebp	ADJ
dti-1548	388	12	-	-	ADJ
dti-1548	388	13	binding	bind	VERB
dti-1548	388	14	region	region	NOUN
dti-1548	388	15	and	and	CCONJ
dti-1548	388	16	adjacent	adjacent	ADJ
dti-1548	388	17	sites	site	NOUN
dti-1548	388	18	regulate	regulate	VERB
dti-1548	388	19	expression	expression	NOUN
dti-1548	388	20	of	of	ADP
dti-1548	388	21	the	the	DET
dti-1548	388	22	adipose	adipose	ADJ
dti-1548	388	23	p2	p2	NOUN
dti-1548	388	24	gene	gene	NOUN
dti-1548	388	25	in	in	ADP
dti-1548	388	26	human	human	ADJ
dti-1548	388	27	preadipocytes	preadipocyte	NOUN
dti-1548	388	28	.	.	PUNCT
dti-1548	389	1	mol	mol	ADP
dti-1548	389	2	cell	cell	NOUN
dti-1548	389	3	biol	biol	NOUN
dti-1548	389	4	.	.	PUNCT
dti-1548	390	1	1991;11(4):2303–2306	1991;11(4):2303–2306	NOUN
dti-1548	390	2	.	.	PUNCT
dti-1548	391	1	32	32	NUM
dti-1548	391	2	.	.	PUNCT
dti-1548	392	1	majdalawieh	majdalawieh	PROPN
dti-1548	392	2	a	a	PRON
dti-1548	392	3	,	,	PUNCT
dti-1548	392	4	ro	ro	PROPN
dti-1548	392	5	hs	hs	PROPN
dti-1548	392	6	.	.	PROPN
dti-1548	392	7	regulation	regulation	NOUN
dti-1548	392	8	of	of	ADP
dti-1548	392	9	ikappabalpha	ikappabalpha	PROPN
dti-1548	392	10	function	function	NOUN
dti-1548	392	11	and	and	CCONJ
dti-1548	392	12	nf	nf	ADJ
dti-1548	392	13	-	-	PUNCT
dti-1548	392	14	kappab	kappab	NOUN
dti-1548	392	15	signaling	signaling	NOUN
dti-1548	392	16	:	:	PUNCT
dti-1548	392	17	aebp1	aebp1	PROPN
dti-1548	392	18	is	be	AUX
dti-1548	392	19	a	a	DET
dti-1548	392	20	novel	novel	ADJ
dti-1548	392	21	proinflammatory	proinflammatory	ADJ
dti-1548	392	22	mediator	mediator	NOUN
dti-1548	392	23	in	in	ADP
dti-1548	392	24	macrophages	macrophage	NOUN
dti-1548	392	25	.	.	PUNCT
dti-1548	393	1	mediators	mediator	NOUN
dti-1548	393	2	inflamm	inflamm	PROPN
dti-1548	393	3	.	.	PUNCT
dti-1548	394	1	2010;2010:823–821	2010;2010:823–821	NUM
dti-1548	394	2	.	.	PUNCT
dti-1548	395	1	33	33	NUM
dti-1548	395	2	.	.	PUNCT
dti-1548	396	1	zhang	zhang	PROPN
dti-1548	396	2	l	l	PROPN
dti-1548	396	3	,	,	PUNCT
dti-1548	396	4	reidy	reidy	PROPN
dti-1548	396	5	sp	sp	PROPN
dti-1548	396	6	,	,	PUNCT
dti-1548	396	7	nicholson	nicholson	PROPN
dti-1548	396	8	te	te	PROPN
dti-1548	396	9	,	,	PUNCT
dti-1548	396	10	et	et	PROPN
dti-1548	396	11	al	al	PROPN
dti-1548	396	12	.	.	PUNCT
dti-1548	397	1	the	the	DET
dti-1548	397	2	role	role	NOUN
dti-1548	397	3	of	of	ADP
dti-1548	397	4	aebp1	aebp1	PROPN
dti-1548	397	5	in	in	ADP
dti-1548	397	6	sexspecific	sexspecific	ADJ
dti-1548	397	7	diet	diet	NOUN
dti-1548	397	8	-	-	PUNCT
dti-1548	397	9	induced	induce	VERB
dti-1548	397	10	obesity	obesity	NOUN
dti-1548	397	11	.	.	PUNCT
dti-1548	398	1	mol	mol	ADP
dti-1548	398	2	med	med	PROPN
dti-1548	398	3	.	.	PUNCT
dti-1548	399	1	2005;11(1–12):39	2005;11(1–12):39	NUM
dti-1548	399	2	.	.	PUNCT
dti-1548	400	1	34	34	NUM
dti-1548	400	2	.	.	PUNCT
dti-1548	400	3	ladha	ladha	PROPN
dti-1548	400	4	j	j	PROPN
dti-1548	400	5	,	,	PUNCT
dti-1548	400	6	sinha	sinha	PROPN
dti-1548	400	7	s	s	PROPN
dti-1548	400	8	,	,	PUNCT
dti-1548	400	9	bhat	bhat	PROPN
dti-1548	400	10	v	v	NOUN
dti-1548	400	11	,	,	PUNCT
dti-1548	400	12	donakonda	donakonda	PROPN
dti-1548	400	13	s	s	PROPN
dti-1548	400	14	,	,	PUNCT
dti-1548	400	15	rao	rao	PROPN
dti-1548	400	16	sm	sm	PROPN
dti-1548	400	17	.	.	PROPN
dti-1548	400	18	identification	identification	NOUN
dti-1548	400	19	of	of	ADP
dti-1548	400	20	genomic	genomic	ADJ
dti-1548	400	21	targets	target	NOUN
dti-1548	400	22	of	of	ADP
dti-1548	400	23	transcription	transcription	NOUN
dti-1548	400	24	factor	factor	NOUN
dti-1548	400	25	aebp1	aebp1	PROPN
dti-1548	400	26	and	and	CCONJ
dti-1548	400	27	its	its	PRON
dti-1548	400	28	role	role	NOUN
dti-1548	400	29	in	in	ADP
dti-1548	400	30	survival	survival	NOUN
dti-1548	400	31	of	of	ADP
dti-1548	400	32	glioma	glioma	NOUN
dti-1548	400	33	cells	cell	NOUN
dti-1548	400	34	.	.	PUNCT
dti-1548	401	1	mol	mol	ADP
dti-1548	401	2	cancer	cancer	NOUN
dti-1548	401	3	res	re	NOUN
dti-1548	401	4	.	.	PUNCT
dti-1548	402	1	2012;10(8	2012;10(8	NUM
dti-1548	402	2	):	):	PUNCT
dti-1548	402	3	1039–1051	1039–1051	NUM
dti-1548	402	4	.	.	PUNCT
dti-1548	402	5	35	35	NUM
dti-1548	402	6	.	.	PUNCT
dti-1548	403	1	han	han	PROPN
dti-1548	403	2	s	s	PROPN
dti-1548	403	3	-	-	PROPN
dti-1548	403	4	j	j	PROPN
dti-1548	403	5	,	,	PUNCT
dti-1548	403	6	cho	cho	PROPN
dti-1548	403	7	yl	yl	NOUN
dti-1548	403	8	,	,	PUNCT
dti-1548	403	9	nam	nam	PROPN
dti-1548	403	10	gh	gh	PROPN
dti-1548	403	11	,	,	PUNCT
dti-1548	403	12	kim	kim	PROPN
dti-1548	403	13	ck	ck	PROPN
dti-1548	403	14	,	,	PUNCT
dti-1548	403	15	seo	seo	PROPN
dti-1548	403	16	j	j	PROPN
dti-1548	403	17	-	-	PUNCT
dti-1548	403	18	s	s	PROPN
dti-1548	403	19	,	,	PUNCT
dti-1548	403	20	ahn	ahn	PROPN
dti-1548	403	21	ws	ws	PROPN
dti-1548	403	22	.	.	PUNCT
dti-1548	404	1	cdna	cdna	PROPN
dti-1548	404	2	microarray	microarray	PROPN
dti-1548	404	3	analysis	analysis	NOUN
dti-1548	404	4	of	of	ADP
dti-1548	404	5	gene	gene	NOUN
dti-1548	404	6	expression	expression	NOUN
dti-1548	404	7	profiles	profile	NOUN
dti-1548	404	8	associated	associate	VERB
dti-1548	404	9	with	with	ADP
dti-1548	404	10	cervical	cervical	ADJ
dti-1548	404	11	cancer	cancer	NOUN
dti-1548	404	12	.	.	PUNCT
dti-1548	405	1	cancer	cancer	NOUN
dti-1548	405	2	res	re	NOUN
dti-1548	405	3	treat	treat	NOUN
dti-1548	405	4	.	.	PUNCT
dti-1548	406	1	2003;35(5):451–459	2003;35(5):451–459	X
dti-1548	406	2	.	.	X
dti-1548	406	3	36	36	NUM
dti-1548	406	4	.	.	PUNCT
dti-1548	406	5	ahn	ahn	PROPN
dti-1548	406	6	ws	ws	PROPN
dti-1548	406	7	,	,	PUNCT
dti-1548	406	8	bae	bae	PROPN
dti-1548	406	9	sm	sm	PROPN
dti-1548	406	10	,	,	PUNCT
dti-1548	406	11	lee	lee	PROPN
dti-1548	406	12	jm	jm	PROPN
dti-1548	406	13	,	,	PUNCT
dti-1548	406	14	et	et	PROPN
dti-1548	406	15	al	al	PROPN
dti-1548	406	16	.	.	PUNCT
dti-1548	406	17	searching	search	VERB
dti-1548	406	18	for	for	ADP
dti-1548	406	19	pathogenic	pathogenic	ADJ
dti-1548	406	20	gene	gene	NOUN
dti-1548	406	21	functions	function	NOUN
dti-1548	406	22	to	to	ADP
dti-1548	406	23	cervical	cervical	ADJ
dti-1548	406	24	cancer	cancer	NOUN
dti-1548	406	25	.	.	PUNCT
dti-1548	407	1	gynecol	gynecol	ADJ
dti-1548	407	2	oncol	oncol	ADJ
dti-1548	407	3	.	.	PUNCT
dti-1548	408	1	2004;93(1):41–48	2004;93(1):41–48	X
dti-1548	408	2	.	.	PUNCT
dti-1548	409	1	37	37	NUM
dti-1548	409	2	.	.	PUNCT
dti-1548	410	1	reddy	reddy	PROPN
dti-1548	410	2	sp	sp	PROPN
dti-1548	410	3	,	,	PUNCT
dti-1548	410	4	britto	britto	NOUN
dti-1548	410	5	r	r	NOUN
dti-1548	410	6	,	,	PUNCT
dti-1548	410	7	vinnakota	vinnakota	ADJ
dti-1548	410	8	k	k	NOUN
dti-1548	410	9	,	,	PUNCT
dti-1548	410	10	et	et	PROPN
dti-1548	410	11	al	al	PROPN
dti-1548	410	12	.	.	PROPN
dti-1548	410	13	novel	novel	ADJ
dti-1548	410	14	glioblastoma	glioblastoma	NOUN
dti-1548	410	15	markers	marker	NOUN
dti-1548	410	16	with	with	ADP
dti-1548	410	17	diagnostic	diagnostic	ADJ
dti-1548	410	18	and	and	CCONJ
dti-1548	410	19	prognostic	prognostic	ADJ
dti-1548	410	20	value	value	NOUN
dti-1548	410	21	identified	identify	VERB
dti-1548	410	22	through	through	ADP
dti-1548	410	23	transcriptome	transcriptome	ADJ
dti-1548	410	24	analysis	analysis	NOUN
dti-1548	410	25	.	.	PUNCT
dti-1548	411	1	clin	clin	PROPN
dti-1548	411	2	cancer	cancer	NOUN
dti-1548	411	3	res	re	NOUN
dti-1548	411	4	.	.	PUNCT
dti-1548	412	1	2008;14(10):2978–2987	2008;14(10):2978–2987	NUM
dti-1548	412	2	.	.	PUNCT
dti-1548	413	1	38	38	NUM
dti-1548	413	2	.	.	PUNCT
dti-1548	414	1	grigoriadis	grigoriadis	PROPN
dti-1548	414	2	a	a	PRON
dti-1548	414	3	,	,	PUNCT
dti-1548	414	4	mackay	mackay	PROPN
dti-1548	414	5	a	a	PROPN
dti-1548	414	6	,	,	PUNCT
dti-1548	414	7	reis	reis	NOUN
dti-1548	414	8	-	-	PUNCT
dti-1548	414	9	filho	filho	NOUN
dti-1548	414	10	js	js	PROPN
dti-1548	414	11	,	,	PUNCT
dti-1548	414	12	et	et	PROPN
dti-1548	414	13	al	al	PROPN
dti-1548	414	14	.	.	PUNCT
dti-1548	415	1	establishment	establishment	NOUN
dti-1548	415	2	of	of	ADP
dti-1548	415	3	the	the	DET
dti-1548	415	4	epithelial	epithelial	ADJ
dti-1548	415	5	-	-	PUNCT
dti-1548	415	6	specific	specific	ADJ
dti-1548	415	7	transcriptome	transcriptome	NOUN
dti-1548	415	8	of	of	ADP
dti-1548	415	9	normal	normal	ADJ
dti-1548	415	10	and	and	CCONJ
dti-1548	415	11	malignant	malignant	ADJ
dti-1548	415	12	human	human	ADJ
dti-1548	415	13	breast	breast	NOUN
dti-1548	415	14	cells	cell	NOUN
dti-1548	415	15	based	base	VERB
dti-1548	415	16	on	on	ADP
dti-1548	415	17	mpss	mpss	PROPN
dti-1548	415	18	and	and	CCONJ
dti-1548	415	19	array	array	VERB
dti-1548	415	20	expression	expression	NOUN
dti-1548	415	21	data	datum	NOUN
dti-1548	415	22	.	.	PUNCT
dti-1548	416	1	breast	breast	NOUN
dti-1548	416	2	cancer	cancer	NOUN
dti-1548	416	3	res	re	NOUN
dti-1548	416	4	.	.	PUNCT
dti-1548	417	1	2006;8(5):r56	2006;8(5):r56	NUM
dti-1548	417	2	.	.	PROPN
dti-1548	417	3	39	39	NUM
dti-1548	417	4	.	.	PUNCT
dti-1548	418	1	wang	wang	PROPN
dti-1548	418	2	l	l	PROPN
dti-1548	418	3	,	,	PUNCT
dti-1548	418	4	yao	yao	PROPN
dti-1548	418	5	j	j	PROPN
dti-1548	418	6	,	,	PUNCT
dti-1548	418	7	sun	sun	PROPN
dti-1548	418	8	h	h	PROPN
dti-1548	418	9	,	,	PUNCT
dti-1548	418	10	et	et	PROPN
dti-1548	418	11	al	al	PROPN
dti-1548	418	12	.	.	PUNCT
dti-1548	418	13	mir-302b	mir-302b	PROPN
dti-1548	418	14	suppresses	suppress	VERB
dti-1548	418	15	cell	cell	NOUN
dti-1548	418	16	invasion	invasion	NOUN
dti-1548	418	17	and	and	CCONJ
dti-1548	418	18	metastasis	metastasis	NOUN
dti-1548	418	19	by	by	ADP
dti-1548	418	20	directly	directly	ADV
dti-1548	418	21	targeting	target	VERB
dti-1548	418	22	akt2	akt2	NOUN
dti-1548	418	23	in	in	ADP
dti-1548	418	24	human	human	ADJ
dti-1548	418	25	hepatocellular	hepatocellular	ADJ
dti-1548	418	26	carcinoma	carcinoma	NOUN
dti-1548	418	27	cells	cell	NOUN
dti-1548	418	28	.	.	PUNCT
dti-1548	419	1	tumor	tumor	NOUN
dti-1548	419	2	biol	biol	PROPN
dti-1548	419	3	.	.	PUNCT
dti-1548	420	1	2016;37(1):847–855	2016;37(1):847–855	X
dti-1548	420	2	.	.	PROPN
dti-1548	420	3	40	40	NUM
dti-1548	420	4	.	.	PUNCT
dti-1548	421	1	jilkova	jilkova	PROPN
dti-1548	421	2	zm	zm	PROPN
dti-1548	421	3	,	,	PUNCT
dti-1548	421	4	kuyucu	kuyucu	PROPN
dti-1548	421	5	az	az	PROPN
dti-1548	421	6	,	,	PUNCT
dti-1548	421	7	kurma	kurma	PROPN
dti-1548	421	8	k	k	PROPN
dti-1548	421	9	,	,	PUNCT
dti-1548	421	10	et	et	PROPN
dti-1548	421	11	al	al	PROPN
dti-1548	421	12	.	.	PROPN
dti-1548	421	13	combination	combination	NOUN
dti-1548	421	14	of	of	ADP
dti-1548	421	15	akt	akt	PROPN
dti-1548	421	16	inhibitor	inhibitor	PROPN
dti-1548	421	17	arq	arq	VERB
dti-1548	421	18	092	092	NUM
dti-1548	421	19	and	and	CCONJ
dti-1548	421	20	sorafenib	sorafenib	NOUN
dti-1548	421	21	potentiates	potentiate	VERB
dti-1548	421	22	inhibition	inhibition	NOUN
dti-1548	421	23	of	of	ADP
dti-1548	421	24	tumor	tumor	NOUN
dti-1548	421	25	progression	progression	NOUN
dti-1548	421	26	in	in	ADP
dti-1548	421	27	cirrhotic	cirrhotic	ADJ
dti-1548	421	28	rat	rat	NOUN
dti-1548	421	29	model	model	NOUN
dti-1548	421	30	of	of	ADP
dti-1548	421	31	hepatocellular	hepatocellular	ADJ
dti-1548	421	32	carcinoma	carcinoma	NOUN
dti-1548	421	33	.	.	PUNCT
dti-1548	422	1	oncotarget	oncotarget	NOUN
dti-1548	422	2	.	.	PUNCT
dti-1548	422	3	2018;9(13):11145–11158	2018;9(13):11145–11158	PROPN
dti-1548	422	4	.	.	PUNCT
dti-1548	423	1	41	41	NUM
dti-1548	423	2	.	.	PUNCT
dti-1548	424	1	ma	ma	PROPN
dti-1548	424	2	c	c	PROPN
dti-1548	424	3	,	,	PUNCT
dti-1548	424	4	yang	yang	PROPN
dti-1548	424	5	y	y	PROPN
dti-1548	424	6	,	,	PUNCT
dti-1548	424	7	wang	wang	PROPN
dti-1548	424	8	j	j	PROPN
dti-1548	424	9	,	,	PUNCT
dti-1548	424	10	et	et	PROPN
dti-1548	424	11	al	al	PROPN
dti-1548	424	12	.	.	PUNCT
dti-1548	425	1	the	the	DET
dti-1548	425	2	apkcι	apkcι	PROPN
dti-1548	425	3	blocking	block	VERB
dti-1548	425	4	agent	agent	NOUN
dti-1548	425	5	atm	atm	NOUN
dti-1548	425	6	negatively	negatively	ADV
dti-1548	425	7	regulates	regulate	VERB
dti-1548	425	8	emt	emt	NOUN
dti-1548	425	9	and	and	CCONJ
dti-1548	425	10	invasion	invasion	NOUN
dti-1548	425	11	of	of	ADP
dti-1548	425	12	hepatocellular	hepatocellular	ADJ
dti-1548	425	13	carcinoma	carcinoma	NOUN
dti-1548	425	14	.	.	PUNCT
dti-1548	426	1	cell	cell	NOUN
dti-1548	426	2	death	death	NOUN
dti-1548	427	1	dis	dis	PROPN
dti-1548	427	2	.	.	PUNCT
dti-1548	428	1	2014;5(3):e1129	2014;5(3):e1129	NUM
dti-1548	428	2	.	.	PUNCT
dti-1548	429	1	42	42	NUM
dti-1548	429	2	.	.	PUNCT
dti-1548	430	1	acevedo	acevedo	PROPN
dti-1548	430	2	-	-	PUNCT
dti-1548	430	3	duncan	duncan	PROPN
dti-1548	430	4	m.	m.	NOUN
dti-1548	430	5	method	method	NOUN
dti-1548	430	6	of	of	ADP
dti-1548	430	7	treating	treat	VERB
dti-1548	430	8	colorectal	colorectal	ADJ
dti-1548	430	9	cancers	cancer	NOUN
dti-1548	430	10	using	use	VERB
dti-1548	430	11	a	a	DET
dti-1548	430	12	pkc	pkc	NOUN
dti-1548	430	13	inhibitor	inhibitor	NOUN
dti-1548	430	14	.	.	PUNCT
dti-1548	431	1	in	in	ADP
dti-1548	431	2	:	:	PUNCT
dti-1548	431	3	google	google	PROPN
dti-1548	431	4	patents	patent	NOUN
dti-1548	431	5	;	;	PUNCT
dti-1548	431	6	2018	2018	NUM
dti-1548	431	7	.	.	PUNCT
dti-1548	432	1	43	43	NUM
dti-1548	432	2	.	.	PUNCT
dti-1548	433	1	wang	wang	PROPN
dti-1548	433	2	j	j	PROPN
dti-1548	433	3	-	-	PROPN
dti-1548	433	4	m	m	PROPN
dti-1548	433	5	,	,	PUNCT
dti-1548	433	6	li	li	PROPN
dti-1548	433	7	q	q	PROPN
dti-1548	433	8	,	,	PUNCT
dti-1548	433	9	du	du	PROPN
dti-1548	433	10	g	g	PROPN
dti-1548	433	11	-	-	PUNCT
dti-1548	433	12	s	s	PROPN
dti-1548	433	13	,	,	PUNCT
dti-1548	433	14	lu	lu	PROPN
dti-1548	433	15	j	j	PROPN
dti-1548	433	16	-	-	PUNCT
dti-1548	433	17	x	x	PROPN
dti-1548	433	18	,	,	PUNCT
dti-1548	433	19	zou	zou	PROPN
dti-1548	433	20	s	s	PROPN
dti-1548	433	21	-	-	PUNCT
dti-1548	433	22	q.	q.	NOUN
dti-1548	433	23	significance	significance	NOUN
dti-1548	433	24	and	and	CCONJ
dti-1548	433	25	expression	expression	NOUN
dti-1548	433	26	of	of	ADP
dti-1548	433	27	atypical	atypical	ADJ
dti-1548	433	28	protein	protein	NOUN
dti-1548	433	29	kinase	kinase	NOUN
dti-1548	433	30	c	c	X
dti-1548	433	31	-	-	PUNCT
dti-1548	433	32	ι	ι	PROPN
dti-1548	433	33	in	in	ADP
dti-1548	433	34	human	human	ADJ
dti-1548	433	35	hepatocellular	hepatocellular	ADJ
dti-1548	433	36	carcinoma	carcinoma	NOUN
dti-1548	433	37	.	.	PUNCT
dti-1548	434	1	j	j	PROPN
dti-1548	434	2	surg	surg	PROPN
dti-1548	434	3	res	re	NOUN
dti-1548	434	4	.	.	PUNCT
dti-1548	435	1	2009;154(1):143–149	2009;154(1):143–149	NUM
dti-1548	435	2	.	.	NOUN
dti-1548	435	3	44	44	NUM
dti-1548	435	4	.	.	PUNCT
dti-1548	436	1	du	du	PROPN
dti-1548	436	2	g	g	PROPN
dti-1548	436	3	-	-	PUNCT
dti-1548	436	4	s	s	PROPN
dti-1548	436	5	,	,	PUNCT
dti-1548	436	6	wang	wang	PROPN
dti-1548	436	7	j	j	PROPN
dti-1548	436	8	-	-	PROPN
dti-1548	436	9	m	m	PROPN
dti-1548	436	10	,	,	PUNCT
dti-1548	436	11	lu	lu	PROPN
dti-1548	436	12	j	j	PROPN
dti-1548	436	13	-	-	PUNCT
dti-1548	436	14	x	x	PROPN
dti-1548	436	15	,	,	PUNCT
dti-1548	436	16	et	et	PROPN
dti-1548	436	17	al	al	PROPN
dti-1548	436	18	.	.	PUNCT
dti-1548	436	19	expression	expression	NOUN
dti-1548	436	20	of	of	ADP
dti-1548	436	21	p	p	NOUN
dti-1548	436	22	-	-	PUNCT
dti-1548	436	23	apkc	apkc	NOUN
dti-1548	436	24	-	-	PUNCT
dti-1548	436	25	ι	ι	NOUN
dti-1548	436	26	,	,	PUNCT
dti-1548	436	27	e	e	NOUN
dti-1548	436	28	-	-	NOUN
dti-1548	436	29	cadherin	cadherin	NOUN
dti-1548	436	30	,	,	PUNCT
dti-1548	436	31	and	and	CCONJ
dti-1548	436	32	β	β	X
dti-1548	436	33	-	-	ADJ
dti-1548	436	34	catenin	catenin	NOUN
dti-1548	436	35	related	relate	VERB
dti-1548	436	36	to	to	ADP
dti-1548	436	37	invasion	invasion	NOUN
dti-1548	436	38	and	and	CCONJ
dti-1548	436	39	metastasis	metastasis	NOUN
dti-1548	436	40	in	in	ADP
dti-1548	436	41	hepatocellular	hepatocellular	ADJ
dti-1548	436	42	carcinoma	carcinoma	NOUN
dti-1548	436	43	.	.	PUNCT
dti-1548	437	1	ann	ann	PROPN
dti-1548	437	2	surg	surg	PROPN
dti-1548	437	3	oncol	oncol	PROPN
dti-1548	437	4	.	.	PUNCT
dti-1548	438	1	2009;16(6):1578–1586	2009;16(6):1578–1586	NUM
dti-1548	438	2	.	.	PUNCT
dti-1548	439	1	45	45	NUM
dti-1548	439	2	.	.	PUNCT
dti-1548	440	1	chiang	chiang	PROPN
dti-1548	440	2	dy	dy	PROPN
dti-1548	440	3	,	,	PUNCT
dti-1548	440	4	villanueva	villanueva	PROPN
dti-1548	440	5	a	a	PROPN
dti-1548	440	6	,	,	PUNCT
dti-1548	440	7	hoshida	hoshida	PROPN
dti-1548	440	8	y	y	PROPN
dti-1548	440	9	,	,	PUNCT
dti-1548	440	10	et	et	PROPN
dti-1548	440	11	al	al	PROPN
dti-1548	440	12	.	.	PROPN
dti-1548	440	13	focal	focal	ADJ
dti-1548	440	14	gains	gain	NOUN
dti-1548	440	15	of	of	ADP
dti-1548	440	16	vegfa	vegfa	NOUN
dti-1548	440	17	and	and	CCONJ
dti-1548	440	18	molecular	molecular	ADJ
dti-1548	440	19	classification	classification	NOUN
dti-1548	440	20	of	of	ADP
dti-1548	440	21	hepatocellular	hepatocellular	ADJ
dti-1548	440	22	carcinoma	carcinoma	NOUN
dti-1548	440	23	.	.	PUNCT
dti-1548	441	1	cancer	cancer	NOUN
dti-1548	441	2	res	re	NOUN
dti-1548	441	3	.	.	PUNCT
dti-1548	442	1	2008;68(16):6779–6788	2008;68(16):6779–6788	NUM
dti-1548	442	2	.	.	PUNCT
dti-1548	443	1	46	46	NUM
dti-1548	443	2	.	.	PUNCT
dti-1548	444	1	boyault	boyault	PROPN
dti-1548	444	2	s	s	PROPN
dti-1548	444	3	,	,	PUNCT
dti-1548	444	4	rickman	rickman	PROPN
dti-1548	444	5	ds	ds	PROPN
dti-1548	444	6	,	,	PUNCT
dti-1548	444	7	de	de	X
dti-1548	444	8	reyniès	reyniès	ADJ
dti-1548	444	9	a	a	PRON
dti-1548	444	10	,	,	PUNCT
dti-1548	444	11	et	et	PROPN
dti-1548	444	12	al	al	PROPN
dti-1548	444	13	.	.	PUNCT
dti-1548	445	1	transcriptome	transcriptome	ADJ
dti-1548	445	2	classification	classification	NOUN
dti-1548	445	3	of	of	ADP
dti-1548	445	4	hcc	hcc	PROPN
dti-1548	445	5	is	be	AUX
dti-1548	445	6	related	relate	VERB
dti-1548	445	7	to	to	ADP
dti-1548	445	8	gene	gene	NOUN
dti-1548	445	9	alterations	alteration	NOUN
dti-1548	445	10	and	and	CCONJ
dti-1548	445	11	to	to	ADP
dti-1548	445	12	new	new	ADJ
dti-1548	445	13	therapeutic	therapeutic	ADJ
dti-1548	445	14	targets	target	NOUN
dti-1548	445	15	.	.	PUNCT
dti-1548	446	1	hepatology	hepatology	NOUN
dti-1548	446	2	.	.	PUNCT
dti-1548	447	1	2007;45(1):42–52	2007;45(1):42–52	NUM
dti-1548	447	2	.	.	PUNCT
dti-1548	448	1	47	47	NUM
dti-1548	448	2	.	.	PUNCT
dti-1548	448	3	de	de	PROPN
dti-1548	448	4	yun	yun	PROPN
dti-1548	448	5	f	f	PROPN
dti-1548	448	6	,	,	PUNCT
dti-1548	448	7	hui	hui	PROPN
dti-1548	449	1	z	z	PROPN
dti-1548	449	2	,	,	PUNCT
dti-1548	449	3	tan	tan	PROPN
dti-1548	449	4	y	y	PROPN
dti-1548	449	5	,	,	PUNCT
dti-1548	449	6	cheng	cheng	PROPN
dti-1548	449	7	rx	rx	PROPN
dti-1548	449	8	.	.	PROPN
dti-1548	449	9	effect	effect	NOUN
dti-1548	449	10	of	of	ADP
dti-1548	449	11	phosphorylation	phosphorylation	NOUN
dti-1548	449	12	of	of	ADP
dti-1548	449	13	mapk	mapk	NOUN
dti-1548	449	14	and	and	CCONJ
dti-1548	449	15	stat3	stat3	NOUN
dti-1548	449	16	and	and	CCONJ
dti-1548	449	17	expression	expression	NOUN
dti-1548	449	18	of	of	ADP
dti-1548	449	19	c	c	NOUN
dti-1548	449	20	-	-	PUNCT
dti-1548	449	21	fos	fos	NOUN
dti-1548	449	22	and	and	CCONJ
dti-1548	449	23	c	c	NOUN
dti-1548	449	24	-	-	PUNCT
dti-1548	449	25	jun	jun	PROPN
dti-1548	449	26	proteins	protein	NOUN
dti-1548	449	27	on	on	ADP
dti-1548	449	28	hepatocarcinogenesis	hepatocarcinogenesis	NOUN
dti-1548	449	29	and	and	CCONJ
dti-1548	449	30	their	their	PRON
dti-1548	449	31	clinical	clinical	ADJ
dti-1548	449	32	significance	significance	NOUN
dti-1548	449	33	.	.	PUNCT
dti-1548	450	1	world	world	PROPN
dti-1548	450	2	j	j	PROPN
dti-1548	450	3	gastroenterol	gastroenterol	PROPN
dti-1548	450	4	.	.	PUNCT
dti-1548	451	1	2001;7(1):33–36	2001;7(1):33–36	NUM
dti-1548	451	2	.	.	PUNCT
dti-1548	452	1	48	48	NUM
dti-1548	452	2	.	.	PUNCT
dti-1548	453	1	he	he	PRON
dti-1548	453	2	s	s	PROPN
dti-1548	453	3	,	,	PUNCT
dti-1548	453	4	zhang	zhang	PROPN
dti-1548	453	5	j	j	PROPN
dti-1548	453	6	,	,	PUNCT
dti-1548	453	7	zhang	zhang	PROPN
dti-1548	453	8	w	w	PROPN
dti-1548	453	9	,	,	PUNCT
dti-1548	453	10	chen	chen	PROPN
dti-1548	453	11	f	f	PROPN
dti-1548	453	12	,	,	PUNCT
dti-1548	453	13	luo	luo	PROPN
dti-1548	453	14	r.	r.	PROPN
dti-1548	453	15	foxa1	foxa1	PROPN
dti-1548	453	16	inhibits	inhibit	VERB
dti-1548	453	17	hepatocellular	hepatocellular	ADJ
dti-1548	453	18	carcinoma	carcinoma	NOUN
dti-1548	453	19	progression	progression	NOUN
dti-1548	453	20	by	by	ADP
dti-1548	453	21	suppressing	suppress	VERB
dti-1548	453	22	pik3r1	pik3r1	ADJ
dti-1548	453	23	expression	expression	NOUN
dti-1548	453	24	in	in	ADP
dti-1548	453	25	male	male	ADJ
dti-1548	453	26	patients	patient	NOUN
dti-1548	453	27	.	.	PUNCT
dti-1548	454	1	j	j	PROPN
dti-1548	454	2	exp	exp	PROPN
dti-1548	454	3	clin	clin	PROPN
dti-1548	454	4	cancer	cancer	NOUN
dti-1548	454	5	res	re	NOUN
dti-1548	454	6	.	.	PUNCT
dti-1548	455	1	2017;36(1):175	2017;36(1):175	NUM
dti-1548	455	2	.	.	PUNCT
dti-1548	456	1	49	49	NUM
dti-1548	456	2	.	.	PUNCT
dti-1548	457	1	rodon	rodon	PROPN
dti-1548	457	2	j	j	PROPN
dti-1548	457	3	,	,	PUNCT
dti-1548	457	4	tabernero	tabernero	PROPN
dti-1548	457	5	j.	j.	PROPN
dti-1548	457	6	improving	improve	VERB
dti-1548	457	7	the	the	DET
dti-1548	457	8	armamentarium	armamentarium	NOUN
dti-1548	457	9	of	of	ADP
dti-1548	457	10	pi3k	pi3k	NOUN
dti-1548	457	11	inhibitors	inhibitor	NOUN
dti-1548	457	12	with	with	ADP
dti-1548	457	13	isoform	isoform	NOUN
dti-1548	457	14	-	-	PUNCT
dti-1548	457	15	selective	selective	ADJ
dti-1548	457	16	agents	agent	NOUN
dti-1548	457	17	:	:	PUNCT
dti-1548	457	18	a	a	DET
dti-1548	457	19	new	new	ADJ
dti-1548	457	20	light	light	NOUN
dti-1548	457	21	in	in	ADP
dti-1548	457	22	the	the	DET
dti-1548	457	23	darkness	darkness	NOUN
dti-1548	457	24	.	.	PUNCT
dti-1548	458	1	cancer	cancer	NOUN
dti-1548	458	2	discov	discov	NOUN
dti-1548	458	3	.	.	PUNCT
dti-1548	459	1	2017;7(7):666–669	2017;7(7):666–669	NUM
dti-1548	459	2	.	.	NOUN
dti-1548	459	3	50	50	NUM
dti-1548	459	4	.	.	PUNCT
dti-1548	460	1	schuster	schuster	PROPN
dti-1548	460	2	mb	mb	PROPN
dti-1548	460	3	,	,	PUNCT
dti-1548	460	4	porse	porse	VERB
dti-1548	460	5	bt	bt	NOUN
dti-1548	460	6	.	.	PUNCT
dti-1548	461	1	c	c	X
dti-1548	461	2	/	/	SYM
dti-1548	461	3	ebpalpha	ebpalpha	PROPN
dti-1548	461	4	:	:	PUNCT
dti-1548	461	5	a	a	DET
dti-1548	461	6	tumour	tumour	ADJ
dti-1548	461	7	suppressor	suppressor	NOUN
dti-1548	461	8	in	in	ADP
dti-1548	461	9	multiple	multiple	ADJ
dti-1548	461	10	tissues	tissue	NOUN
dti-1548	461	11	?	?	PUNCT
dti-1548	462	1	biochim	biochim	PROPN
dti-1548	462	2	biophys	biophy	NOUN
dti-1548	462	3	acta	acta	PROPN
dti-1548	462	4	.	.	PUNCT
dti-1548	463	1	2006;1766(1):88–103	2006;1766(1):88–103	NUM
dti-1548	463	2	.	.	X
dti-1548	464	1	51	51	NUM
dti-1548	464	2	.	.	X
dti-1548	464	3	costa	costa	PROPN
dti-1548	464	4	db	db	PROPN
dti-1548	464	5	,	,	PUNCT
dti-1548	464	6	li	li	PROPN
dti-1548	464	7	s	s	PROPN
dti-1548	464	8	,	,	PUNCT
dti-1548	465	1	kocher	kocher	PROPN
dti-1548	465	2	o	o	NOUN
dti-1548	465	3	,	,	PUNCT
dti-1548	465	4	et	et	PROPN
dti-1548	465	5	al	al	PROPN
dti-1548	465	6	.	.	PROPN
dti-1548	465	7	immunohistochemical	immunohistochemical	ADJ
dti-1548	465	8	analysis	analysis	NOUN
dti-1548	465	9	of	of	ADP
dti-1548	465	10	c	c	NOUN
dti-1548	465	11	/	/	SYM
dti-1548	465	12	ebpalpha	ebpalpha	PROPN
dti-1548	465	13	in	in	ADP
dti-1548	465	14	non	non	ADJ
dti-1548	465	15	-	-	ADJ
dti-1548	465	16	small	small	ADJ
dti-1548	465	17	cell	cell	NOUN
dti-1548	465	18	lung	lung	NOUN
dti-1548	465	19	cancer	cancer	NOUN
dti-1548	465	20	reveals	reveal	VERB
dti-1548	465	21	frequent	frequent	ADJ
dti-1548	465	22	down	down	ADP
dti-1548	465	23	-	-	PUNCT
dti-1548	465	24	regulation	regulation	NOUN
dti-1548	465	25	in	in	ADP
dti-1548	465	26	stage	stage	NOUN
dti-1548	465	27	ii	ii	NOUN
dti-1548	465	28	and	and	CCONJ
dti-1548	465	29	iiia	iiia	VERB
dti-1548	465	30	tumors	tumor	NOUN
dti-1548	465	31	:	:	PUNCT
dti-1548	465	32	a	a	DET
dti-1548	465	33	correlative	correlative	ADJ
dti-1548	465	34	study	study	NOUN
dti-1548	465	35	of	of	ADP
dti-1548	465	36	e3590	e3590	PROPN
dti-1548	465	37	.	.	PUNCT
dti-1548	465	38	lung	lung	NOUN
dti-1548	465	39	cancer	cancer	NOUN
dti-1548	465	40	(	(	PUNCT
dti-1548	465	41	amsterdam	amsterdam	PROPN
dti-1548	465	42	,	,	PUNCT
dti-1548	465	43	netherlands	netherlands	PROPN
dti-1548	465	44	)	)	PUNCT
dti-1548	465	45	.	.	PUNCT
dti-1548	466	1	2007	2007	NUM
dti-1548	466	2	;	;	PUNCT
dti-1548	466	3	56(1):97–103	56(1):97–103	NUM
dti-1548	466	4	.	.	NOUN
dti-1548	466	5	52	52	NUM
dti-1548	466	6	.	.	PUNCT
dti-1548	467	1	gery	gery	PROPN
dti-1548	467	2	s	s	PROPN
dti-1548	467	3	,	,	PUNCT
dti-1548	467	4	tanosaki	tanosaki	PROPN
dti-1548	467	5	s	s	PROPN
dti-1548	467	6	,	,	PUNCT
dti-1548	467	7	bose	bose	PROPN
dti-1548	467	8	s	s	PROPN
dti-1548	467	9	,	,	PUNCT
dti-1548	467	10	bose	bose	NOUN
dti-1548	467	11	n	n	CCONJ
dti-1548	467	12	,	,	PUNCT
dti-1548	467	13	vadgama	vadgama	PROPN
dti-1548	467	14	j	j	PROPN
dti-1548	467	15	,	,	PUNCT
dti-1548	467	16	koeffler	koeffler	PROPN
dti-1548	467	17	hp	hp	PROPN
dti-1548	467	18	.	.	PROPN
dti-1548	467	19	down	down	ADP
dti-1548	467	20	-	-	PUNCT
dti-1548	467	21	regulation	regulation	NOUN
dti-1548	467	22	and	and	CCONJ
dti-1548	467	23	growth	growth	NOUN
dti-1548	467	24	inhibitory	inhibitory	ADJ
dti-1548	467	25	role	role	NOUN
dti-1548	467	26	of	of	ADP
dti-1548	467	27	c	c	NOUN
dti-1548	467	28	/	/	SYM
dti-1548	467	29	ebpalpha	ebpalpha	PROPN
dti-1548	467	30	in	in	ADP
dti-1548	467	31	breast	breast	NOUN
dti-1548	467	32	cancer	cancer	NOUN
dti-1548	467	33	.	.	PUNCT
dti-1548	468	1	clin	clin	PROPN
dti-1548	468	2	cancer	cancer	NOUN
dti-1548	468	3	res	re	NOUN
dti-1548	468	4	.	.	PUNCT
dti-1548	469	1	2005;11(9):3184–3190	2005;11(9):3184–3190	NOUN
dti-1548	469	2	.	.	PUNCT
dti-1548	470	1	53	53	NUM
dti-1548	470	2	.	.	X
dti-1548	470	3	bennett	bennett	PROPN
dti-1548	470	4	kl	kl	PROPN
dti-1548	470	5	,	,	PUNCT
dti-1548	470	6	hackanson	hackanson	PROPN
dti-1548	470	7	b	b	PROPN
dti-1548	470	8	,	,	PUNCT
dti-1548	470	9	smith	smith	PROPN
dti-1548	470	10	lt	lt	PROPN
dti-1548	470	11	,	,	PUNCT
dti-1548	470	12	et	et	PROPN
dti-1548	470	13	al	al	PROPN
dti-1548	470	14	.	.	PROPN
dti-1548	470	15	tumor	tumor	PROPN
dti-1548	470	16	suppressor	suppressor	NOUN
dti-1548	470	17	activity	activity	NOUN
dti-1548	470	18	of	of	ADP
dti-1548	470	19	ccaat	ccaat	NOUN
dti-1548	470	20	/	/	SYM
dti-1548	470	21	enhancer	enhancer	NOUN
dti-1548	470	22	binding	bind	VERB
dti-1548	470	23	protein	protein	NOUN
dti-1548	470	24	alpha	alpha	NOUN
dti-1548	470	25	is	be	AUX
dti-1548	470	26	epigenetically	epigenetically	ADV
dti-1548	470	27	down	down	ADV
dti-1548	470	28	-	-	PUNCT
dti-1548	470	29	regulated	regulate	VERB
dti-1548	470	30	in	in	ADP
dti-1548	470	31	head	head	NOUN
dti-1548	470	32	and	and	CCONJ
dti-1548	470	33	neck	neck	VERB
dti-1548	470	34	squamous	squamous	ADJ
dti-1548	470	35	cell	cell	NOUN
dti-1548	470	36	carcinoma	carcinoma	NOUN
dti-1548	470	37	.	.	PUNCT
dti-1548	471	1	cancer	cancer	NOUN
dti-1548	471	2	res	re	NOUN
dti-1548	471	3	.	.	PUNCT
dti-1548	472	1	2007;67(10):4657–4664	2007;67(10):4657–4664	NUM
dti-1548	472	2	.	.	NOUN
dti-1548	472	3	mabrouk	mabrouk	PROPN
dti-1548	472	4	et	et	NOUN
dti-1548	472	5	al	al	PROPN
dti-1548	472	6	11	11	NUM
dti-1548	472	7	©	©	PROPN
dti-1548	472	8	2020	2020	NUM
dti-1548	472	9	the	the	DET
dti-1548	472	10	authors	author	NOUN
dti-1548	472	11	.	.	PUNCT
dti-1548	473	1	published	publish	VERB
dti-1548	473	2	by	by	ADP
dti-1548	473	3	aboutscience	aboutscience	NOUN
dti-1548	473	4	54	54	NUM
dti-1548	473	5	.	.	PUNCT
dti-1548	474	1	tseng	tseng	PROPN
dti-1548	474	2	hh	hh	PROPN
dti-1548	474	3	,	,	PUNCT
dti-1548	474	4	hwang	hwang	PROPN
dti-1548	474	5	yh	yh	PROPN
dti-1548	474	6	,	,	PUNCT
dti-1548	474	7	yeh	yeh	PROPN
dti-1548	474	8	kt	kt	PROPN
dti-1548	474	9	,	,	PUNCT
dti-1548	474	10	chang	chang	PROPN
dti-1548	474	11	jg	jg	PROPN
dti-1548	474	12	,	,	PUNCT
dti-1548	474	13	chen	chen	PROPN
dti-1548	474	14	yl	yl	PROPN
dti-1548	474	15	,	,	PUNCT
dti-1548	474	16	yu	yu	PROPN
dti-1548	474	17	hs	hs	PROPN
dti-1548	474	18	.	.	PROPN
dti-1548	474	19	reduced	reduce	VERB
dti-1548	474	20	expression	expression	NOUN
dti-1548	474	21	of	of	ADP
dti-1548	474	22	c	c	PROPN
dti-1548	474	23	/	/	SYM
dti-1548	474	24	ebpalpha	ebpalpha	NOUN
dti-1548	474	25	protein	protein	NOUN
dti-1548	474	26	in	in	ADP
dti-1548	474	27	hepatocellular	hepatocellular	ADJ
dti-1548	474	28	carcinoma	carcinoma	NOUN
dti-1548	474	29	is	be	AUX
dti-1548	474	30	associated	associate	VERB
dti-1548	474	31	with	with	ADP
dti-1548	474	32	advanced	advanced	ADJ
dti-1548	474	33	tumor	tumor	NOUN
dti-1548	474	34	stage	stage	NOUN
dti-1548	474	35	and	and	CCONJ
dti-1548	474	36	shortened	shorten	VERB
dti-1548	474	37	patient	patient	ADJ
dti-1548	474	38	survival	survival	NOUN
dti-1548	474	39	.	.	PUNCT
dti-1548	475	1	j	j	PROPN
dti-1548	475	2	cancer	cancer	NOUN
dti-1548	475	3	res	re	VERB
dti-1548	475	4	clin	clin	PROPN
dti-1548	475	5	oncol	oncol	PROPN
dti-1548	475	6	.	.	PUNCT
dti-1548	476	1	2009;135(2	2009;135(2	NUM
dti-1548	476	2	):	):	PUNCT
dti-1548	476	3	241–247	241–247	NUM
dti-1548	476	4	.	.	PUNCT
dti-1548	477	1	55	55	NUM
dti-1548	477	2	.	.	PUNCT
dti-1548	478	1	tomizawa	tomizawa	PROPN
dti-1548	478	2	m	m	PROPN
dti-1548	478	3	,	,	PUNCT
dti-1548	478	4	watanabe	watanabe	PROPN
dti-1548	478	5	k	k	PROPN
dti-1548	478	6	,	,	PUNCT
dti-1548	478	7	saisho	saisho	PROPN
dti-1548	478	8	h	h	PROPN
dti-1548	478	9	,	,	PUNCT
dti-1548	478	10	nakagawara	nakagawara	NOUN
dti-1548	478	11	a	a	NOUN
dti-1548	478	12	,	,	PUNCT
dti-1548	478	13	tagawa	tagawa	PROPN
dti-1548	478	14	m.	m.	NOUN
dti-1548	479	1	down	down	ADV
dti-1548	479	2	-	-	PUNCT
dti-1548	479	3	regulated	regulate	VERB
dti-1548	479	4	expression	expression	NOUN
dti-1548	479	5	of	of	ADP
dti-1548	479	6	the	the	DET
dti-1548	479	7	ccaat	ccaat	NOUN
dti-1548	479	8	/	/	SYM
dti-1548	479	9	enhancer	enhancer	NOUN
dti-1548	479	10	binding	bind	VERB
dti-1548	479	11	protein	protein	NOUN
dti-1548	479	12	alpha	alpha	NOUN
dti-1548	479	13	and	and	CCONJ
dti-1548	479	14	beta	beta	ADJ
dti-1548	479	15	genes	gene	NOUN
dti-1548	479	16	in	in	ADP
dti-1548	479	17	human	human	ADJ
dti-1548	479	18	hepatocellular	hepatocellular	ADJ
dti-1548	479	19	carcinoma	carcinoma	NOUN
dti-1548	479	20	:	:	PUNCT
dti-1548	479	21	a	a	DET
dti-1548	479	22	possible	possible	ADJ
dti-1548	479	23	prognostic	prognostic	ADJ
dti-1548	479	24	marker	marker	NOUN
dti-1548	479	25	.	.	PUNCT
dti-1548	480	1	anticancer	anticancer	NOUN
dti-1548	480	2	res	re	NOUN
dti-1548	480	3	.	.	PUNCT
dti-1548	481	1	2003;23(1a):351–354	2003;23(1a):351–354	NUM
dti-1548	481	2	.	.	X
dti-1548	482	1	56	56	NUM
dti-1548	482	2	.	.	PUNCT
dti-1548	483	1	voutila	voutila	PROPN
dti-1548	483	2	j	j	PROPN
dti-1548	483	3	,	,	PUNCT
dti-1548	483	4	reebye	reebye	PROPN
dti-1548	483	5	v	v	PROPN
dti-1548	483	6	,	,	PUNCT
dti-1548	483	7	roberts	roberts	PROPN
dti-1548	483	8	tc	tc	PROPN
dti-1548	483	9	,	,	PUNCT
dti-1548	483	10	et	et	PROPN
dti-1548	483	11	al	al	PROPN
dti-1548	483	12	.	.	PROPN
dti-1548	483	13	development	development	NOUN
dti-1548	483	14	and	and	CCONJ
dti-1548	483	15	mechanism	mechanism	NOUN
dti-1548	483	16	of	of	ADP
dti-1548	483	17	small	small	ADJ
dti-1548	483	18	activating	activate	VERB
dti-1548	483	19	rna	rna	NOUN
dti-1548	483	20	targeting	targeting	NOUN
dti-1548	483	21	cebpa	cebpa	NOUN
dti-1548	483	22	,	,	PUNCT
dti-1548	483	23	a	a	DET
dti-1548	483	24	novel	novel	NOUN
dti-1548	483	25	therapeutic	therapeutic	ADJ
dti-1548	483	26	in	in	ADP
dti-1548	483	27	clinical	clinical	ADJ
dti-1548	483	28	trials	trial	NOUN
dti-1548	483	29	for	for	ADP
dti-1548	483	30	liver	liver	NOUN
dti-1548	483	31	cancer	cancer	NOUN
dti-1548	483	32	.	.	PUNCT
dti-1548	484	1	mol	mol	ADP
dti-1548	484	2	ther	ther	ADV
dti-1548	484	3	.	.	PUNCT
dti-1548	485	1	2017;25(12	2017;25(12	NUM
dti-1548	485	2	):	):	PUNCT
dti-1548	485	3	2705–2714	2705–2714	NUM
dti-1548	485	4	.	.	PUNCT
dti-1548	486	1	57	57	NUM
dti-1548	486	2	.	.	PUNCT
dti-1548	487	1	reebye	reebye	PROPN
dti-1548	487	2	v	v	PROPN
dti-1548	487	3	,	,	PUNCT
dti-1548	487	4	huang	huang	PROPN
dti-1548	487	5	kw	kw	PROPN
dti-1548	487	6	.	.	PUNCT
dti-1548	487	7	gene	gene	NOUN
dti-1548	487	8	activation	activation	NOUN
dti-1548	487	9	of	of	ADP
dti-1548	487	10	cebpa	cebpa	NOUN
dti-1548	487	11	using	use	VERB
dti-1548	487	12	sarna	sarna	NOUN
dti-1548	487	13	:	:	PUNCT
dti-1548	487	14	preclinical	preclinical	ADJ
dti-1548	487	15	studies	study	NOUN
dti-1548	487	16	of	of	ADP
dti-1548	487	17	the	the	DET
dti-1548	487	18	first	first	ADJ
dti-1548	487	19	in	in	ADP
dti-1548	487	20	human	human	PROPN
dti-1548	487	21	sarna	sarna	PROPN
dti-1548	487	22	drug	drug	NOUN
dti-1548	487	23	candidate	candidate	NOUN
dti-1548	487	24	for	for	ADP
dti-1548	487	25	liver	liver	NOUN
dti-1548	487	26	cancer	cancer	NOUN
dti-1548	487	27	.	.	PUNCT
dti-1548	488	1	2018;37(24):3216	2018;37(24):3216	NUM
dti-1548	488	2	-	-	SYM
dti-1548	488	3	28	28	NUM
dti-1548	488	4	.	.	PUNCT
dti-1548	489	1	58	58	NUM
dti-1548	489	2	.	.	PUNCT
dti-1548	490	1	huang	huang	PROPN
dti-1548	490	2	l	l	PROPN
dti-1548	490	3	,	,	PUNCT
dti-1548	490	4	watanabe	watanabe	PROPN
dti-1548	490	5	m	m	PROPN
dti-1548	490	6	,	,	PUNCT
dti-1548	490	7	chikamori	chikamori	PROPN
dti-1548	490	8	m	m	PROPN
dti-1548	490	9	,	,	PUNCT
dti-1548	490	10	et	et	PROPN
dti-1548	490	11	al	al	PROPN
dti-1548	490	12	.	.	PROPN
dti-1548	490	13	unique	unique	ADJ
dti-1548	490	14	role	role	NOUN
dti-1548	490	15	of	of	ADP
dti-1548	490	16	snt-2	snt-2	NOUN
dti-1548	490	17	/	/	SYM
dti-1548	490	18	frs2β	frs2β	PROPN
dti-1548	490	19	/	/	SYM
dti-1548	490	20	frs3	frs3	NOUN
dti-1548	490	21	docking	docking	NOUN
dti-1548	490	22	/	/	SYM
dti-1548	490	23	adaptor	adaptor	NOUN
dti-1548	490	24	protein	protein	NOUN
dti-1548	490	25	for	for	ADP
dti-1548	490	26	negative	negative	ADJ
dti-1548	490	27	regulation	regulation	NOUN
dti-1548	490	28	in	in	ADP
dti-1548	490	29	egf	egf	PROPN
dti-1548	490	30	receptor	receptor	NOUN
dti-1548	490	31	tyrosine	tyrosine	PROPN
dti-1548	490	32	kinase	kinase	PROPN
dti-1548	490	33	signaling	signal	VERB
dti-1548	490	34	pathways	pathway	NOUN
dti-1548	490	35	.	.	PUNCT
dti-1548	491	1	oncogene	oncogene	NOUN
dti-1548	491	2	.	.	PUNCT
dti-1548	492	1	2006;25(49):6457	2006;25(49):6457	NUM
dti-1548	492	2	.	.	PROPN
dti-1548	492	3	59	59	NUM
dti-1548	492	4	.	.	PUNCT
dti-1548	493	1	iejima	iejima	PROPN
dti-1548	493	2	d	d	PROPN
dti-1548	493	3	,	,	PUNCT
dti-1548	493	4	minegishi	minegishi	PROPN
dti-1548	493	5	y	y	PROPN
dti-1548	493	6	,	,	PUNCT
dti-1548	493	7	takenaka	takenaka	ADV
dti-1548	493	8	k	k	X
dti-1548	493	9	,	,	PUNCT
dti-1548	493	10	et	et	PROPN
dti-1548	493	11	al	al	PROPN
dti-1548	493	12	.	.	PUNCT
dti-1548	494	1	frs2β	frs2β	PROPN
dti-1548	494	2	,	,	PUNCT
dti-1548	494	3	a	a	DET
dti-1548	494	4	potential	potential	ADJ
dti-1548	494	5	prognostic	prognostic	ADJ
dti-1548	494	6	gene	gene	NOUN
dti-1548	494	7	for	for	ADP
dti-1548	494	8	non	non	ADJ
dti-1548	494	9	-	-	ADJ
dti-1548	494	10	small	small	ADJ
dti-1548	494	11	cell	cell	NOUN
dti-1548	494	12	lung	lung	NOUN
dti-1548	494	13	cancer	cancer	NOUN
dti-1548	494	14	,	,	PUNCT
dti-1548	494	15	encodes	encode	VERB
dti-1548	494	16	a	a	DET
dti-1548	494	17	feedback	feedback	NOUN
dti-1548	494	18	inhibitor	inhibitor	NOUN
dti-1548	494	19	of	of	ADP
dti-1548	494	20	egf	egf	PROPN
dti-1548	494	21	receptor	receptor	NOUN
dti-1548	494	22	family	family	NOUN
dti-1548	494	23	members	member	NOUN
dti-1548	494	24	by	by	ADP
dti-1548	494	25	erk	erk	PROPN
dti-1548	494	26	binding	bind	VERB
dti-1548	494	27	.	.	PUNCT
dti-1548	495	1	oncogene	oncogene	NOUN
dti-1548	495	2	.	.	PUNCT
dti-1548	496	1	2010;29(21):3087	2010;29(21):3087	X
dti-1548	496	2	.	.	NOUN
dti-1548	496	3	60	60	NUM
dti-1548	496	4	.	.	PUNCT
dti-1548	497	1	turhal	turhal	NOUN
dti-1548	497	2	n	n	CCONJ
dti-1548	497	3	,	,	PUNCT
dti-1548	497	4	bas	bas	PROPN
dti-1548	497	5	e	e	NOUN
dti-1548	497	6	,	,	PUNCT
dti-1548	497	7	er	er	INTJ
dti-1548	497	8	o	o	INTJ
dti-1548	497	9	,	,	PUNCT
dti-1548	497	10	et	et	PROPN
dti-1548	497	11	al	al	PROPN
dti-1548	497	12	.	.	PUNCT
dti-1548	497	13	ercc1	ercc1	PROPN
dti-1548	497	14	is	be	AUX
dti-1548	497	15	not	not	PART
dti-1548	497	16	expressed	express	VERB
dti-1548	497	17	in	in	ADP
dti-1548	497	18	hepatocellular	hepatocellular	ADJ
dti-1548	497	19	cancer	cancer	NOUN
dti-1548	497	20	:	:	PUNCT
dti-1548	497	21	a	a	DET
dti-1548	497	22	turkish	turkish	ADJ
dti-1548	497	23	oncology	oncology	NOUN
dti-1548	497	24	group	group	NOUN
dti-1548	497	25	,	,	PUNCT
dti-1548	497	26	gastrointestinal	gastrointestinal	ADJ
dti-1548	497	27	oncology	oncology	NOUN
dti-1548	497	28	subgroup	subgroup	NOUN
dti-1548	497	29	study	study	NOUN
dti-1548	497	30	.	.	PUNCT
dti-1548	498	1	j	j	PROPN
dti-1548	498	2	buon	buon	VERB
dti-1548	498	3	.	.	PUNCT
dti-1548	499	1	2010;15(4):794–796	2010;15(4):794–796	X
dti-1548	499	2	.	.	PROPN
dti-1548	499	3	61	61	NUM
dti-1548	499	4	.	.	PUNCT
dti-1548	500	1	cheng	cheng	PROPN
dti-1548	500	2	l	l	PROPN
dti-1548	500	3	,	,	PUNCT
dti-1548	500	4	spitz	spitz	PROPN
dti-1548	500	5	mr	mr	PROPN
dti-1548	500	6	,	,	PUNCT
dti-1548	500	7	hong	hong	PROPN
dti-1548	500	8	wk	wk	PROPN
dti-1548	500	9	,	,	PUNCT
dti-1548	500	10	wei	wei	PROPN
dti-1548	500	11	q.	q.	PROPN
dti-1548	500	12	reduced	reduce	VERB
dti-1548	500	13	expression	expression	NOUN
dti-1548	500	14	levels	level	NOUN
dti-1548	500	15	of	of	ADP
dti-1548	500	16	nucleotide	nucleotide	ADJ
dti-1548	500	17	excision	excision	NOUN
dti-1548	500	18	repair	repair	NOUN
dti-1548	500	19	genes	gene	NOUN
dti-1548	500	20	in	in	ADP
dti-1548	500	21	lung	lung	NOUN
dti-1548	500	22	cancer	cancer	NOUN
dti-1548	500	23	:	:	PUNCT
dti-1548	500	24	a	a	DET
dti-1548	500	25	casecontrol	casecontrol	NOUN
dti-1548	500	26	analysis	analysis	NOUN
dti-1548	500	27	.	.	PUNCT
dti-1548	501	1	carcinogenesis	carcinogenesis	NOUN
dti-1548	501	2	.	.	PUNCT
dti-1548	502	1	2000;21(8):1527–1530	2000;21(8):1527–1530	NUM
dti-1548	502	2	.	.	PUNCT
dti-1548	503	1	62	62	NUM
dti-1548	503	2	.	.	PUNCT
dti-1548	504	1	simon	simon	PROPN
dti-1548	504	2	gr	gr	PROPN
dti-1548	504	3	,	,	PUNCT
dti-1548	504	4	sharma	sharma	PROPN
dti-1548	504	5	s	s	PROPN
dti-1548	504	6	,	,	PUNCT
dti-1548	504	7	cantor	cantor	PROPN
dti-1548	504	8	a	a	PROPN
dti-1548	504	9	,	,	PUNCT
dti-1548	504	10	smith	smith	PROPN
dti-1548	504	11	p	p	PROPN
dti-1548	504	12	,	,	PUNCT
dti-1548	504	13	bepler	bepler	PROPN
dti-1548	504	14	g.	g.	PROPN
dti-1548	504	15	ercc1	ercc1	PROPN
dti-1548	504	16	expression	expression	NOUN
dti-1548	504	17	is	be	AUX
dti-1548	504	18	a	a	DET
dti-1548	504	19	predictor	predictor	NOUN
dti-1548	504	20	of	of	ADP
dti-1548	504	21	survival	survival	NOUN
dti-1548	504	22	in	in	ADP
dti-1548	504	23	resected	resect	VERB
dti-1548	504	24	patients	patient	NOUN
dti-1548	504	25	with	with	ADP
dti-1548	504	26	non	non	ADJ
dti-1548	504	27	-	-	ADJ
dti-1548	504	28	small	small	ADJ
dti-1548	504	29	cell	cell	NOUN
dti-1548	504	30	lung	lung	NOUN
dti-1548	504	31	cancer	cancer	NOUN
dti-1548	504	32	.	.	PUNCT
dti-1548	505	1	chest	chest	NOUN
dti-1548	505	2	.	.	PUNCT
dti-1548	506	1	2005;127(3):978–983	2005;127(3):978–983	X
dti-1548	506	2	.	.	PROPN
dti-1548	507	1	63	63	NUM
dti-1548	507	2	.	.	PUNCT
dti-1548	508	1	cheng	cheng	PROPN
dti-1548	508	2	l	l	PROPN
dti-1548	508	3	,	,	PUNCT
dti-1548	508	4	sturgis	sturgis	PROPN
dti-1548	508	5	em	em	PRON
dti-1548	508	6	,	,	PUNCT
dti-1548	508	7	eicher	eicher	PROPN
dti-1548	508	8	sa	sa	PROPN
dti-1548	508	9	,	,	PUNCT
dti-1548	508	10	spitz	spitz	PROPN
dti-1548	508	11	mr	mr	PROPN
dti-1548	508	12	,	,	PUNCT
dti-1548	508	13	wei	wei	PROPN
dti-1548	508	14	q.	q.	PROPN
dti-1548	508	15	expression	expression	NOUN
dti-1548	508	16	of	of	ADP
dti-1548	508	17	nucleotide	nucleotide	ADJ
dti-1548	508	18	excision	excision	NOUN
dti-1548	508	19	repair	repair	NOUN
dti-1548	508	20	genes	gene	NOUN
dti-1548	508	21	and	and	CCONJ
dti-1548	508	22	the	the	DET
dti-1548	508	23	risk	risk	NOUN
dti-1548	508	24	for	for	ADP
dti-1548	508	25	squamous	squamous	ADJ
dti-1548	508	26	cell	cell	NOUN
dti-1548	508	27	carcinoma	carcinoma	NOUN
dti-1548	508	28	of	of	ADP
dti-1548	508	29	the	the	DET
dti-1548	508	30	head	head	NOUN
dti-1548	508	31	and	and	CCONJ
dti-1548	508	32	neck	neck	NOUN
dti-1548	508	33	.	.	PUNCT
dti-1548	509	1	cancer	cancer	NOUN
dti-1548	509	2	.	.	PUNCT
dti-1548	510	1	2002;94(2):393–397	2002;94(2):393–397	NUM
dti-1548	510	2	.	.	NOUN
dti-1548	511	1	64	64	NUM
dti-1548	511	2	.	.	PUNCT
dti-1548	512	1	ueda	ueda	PROPN
dti-1548	512	2	s	s	PROPN
dti-1548	512	3	,	,	PUNCT
dti-1548	512	4	shirabe	shirabe	PROPN
dti-1548	512	5	k	k	PROPN
dti-1548	512	6	,	,	PUNCT
dti-1548	512	7	morita	morita	PROPN
dti-1548	512	8	k	k	PROPN
dti-1548	512	9	,	,	PUNCT
dti-1548	512	10	et	et	PROPN
dti-1548	512	11	al	al	PROPN
dti-1548	512	12	.	.	PUNCT
dti-1548	512	13	evaluation	evaluation	NOUN
dti-1548	512	14	of	of	ADP
dti-1548	512	15	ercc1	ercc1	NOUN
dti-1548	512	16	expression	expression	NOUN
dti-1548	512	17	for	for	ADP
dti-1548	512	18	cisplatin	cisplatin	NOUN
dti-1548	512	19	sensitivity	sensitivity	NOUN
dti-1548	512	20	in	in	ADP
dti-1548	512	21	human	human	ADJ
dti-1548	512	22	hepatocellular	hepatocellular	ADJ
dti-1548	512	23	carcinoma	carcinoma	NOUN
dti-1548	512	24	.	.	PUNCT
dti-1548	513	1	ann	ann	PROPN
dti-1548	513	2	surg	surg	PROPN
dti-1548	513	3	oncol	oncol	PROPN
dti-1548	513	4	.	.	PUNCT
dti-1548	514	1	2011;18(4):1204–1211	2011;18(4):1204–1211	NUM
dti-1548	514	2	.	.	PUNCT
dti-1548	515	1	65	65	NUM
dti-1548	515	2	.	.	PUNCT
dti-1548	516	1	fautrel	fautrel	PROPN
dti-1548	516	2	a	a	X
dti-1548	516	3	,	,	PUNCT
dti-1548	516	4	andrieux	andrieux	PROPN
dti-1548	516	5	l	l	PROPN
dti-1548	516	6	,	,	PUNCT
dti-1548	516	7	musso	musso	PROPN
dti-1548	516	8	o	o	PROPN
dti-1548	516	9	,	,	PUNCT
dti-1548	516	10	boudjema	boudjema	X
dti-1548	516	11	k	k	NOUN
dti-1548	516	12	,	,	PUNCT
dti-1548	516	13	guillouzo	guillouzo	NOUN
dti-1548	516	14	a	a	PRON
dti-1548	516	15	,	,	PUNCT
dti-1548	516	16	langouët	langouët	ADJ
dti-1548	516	17	s	s	PART
dti-1548	516	18	:	:	PUNCT
dti-1548	516	19	overexpression	overexpression	NOUN
dti-1548	516	20	of	of	ADP
dti-1548	516	21	the	the	DET
dti-1548	516	22	two	two	NUM
dti-1548	516	23	nucleotide	nucleotide	ADJ
dti-1548	516	24	excision	excision	NOUN
dti-1548	516	25	repair	repair	NOUN
dti-1548	516	26	genes	gene	NOUN
dti-1548	516	27	ercc1	ercc1	NOUN
dti-1548	516	28	and	and	CCONJ
dti-1548	516	29	xpc	xpc	PROPN
dti-1548	516	30	in	in	ADP
dti-1548	516	31	human	human	ADJ
dti-1548	516	32	hepatocellular	hepatocellular	ADJ
dti-1548	516	33	carcinoma	carcinoma	NOUN
dti-1548	516	34	.	.	PUNCT
dti-1548	517	1	j	j	PROPN
dti-1548	517	2	hepatol	hepatol	ADJ
dti-1548	517	3	.	.	PUNCT
dti-1548	518	1	2005;43(2):288–293	2005;43(2):288–293	X
dti-1548	518	2	.	.	X
dti-1548	518	3	66	66	NUM
dti-1548	518	4	.	.	PUNCT
dti-1548	519	1	lopez	lopez	PROPN
dti-1548	519	2	pm	pm	PROPN
dti-1548	519	3	,	,	PUNCT
dti-1548	519	4	patel	patel	PROPN
dti-1548	519	5	p	p	X
dti-1548	519	6	,	,	PUNCT
dti-1548	519	7	uva	uva	PROPN
dti-1548	519	8	p	p	PROPN
dti-1548	519	9	,	,	PUNCT
dti-1548	519	10	villanueva	villanueva	PROPN
dti-1548	519	11	a	a	PRON
dti-1548	519	12	,	,	PUNCT
dti-1548	519	13	llovet	llovet	PROPN
dti-1548	519	14	jm	jm	PROPN
dti-1548	519	15	.	.	PROPN
dti-1548	519	16	current	current	ADJ
dti-1548	519	17	management	management	NOUN
dti-1548	519	18	of	of	ADP
dti-1548	519	19	liver	liver	NOUN
dti-1548	519	20	cancer	cancer	NOUN
dti-1548	519	21	.	.	PUNCT
dti-1548	520	1	eur	eur	PROPN
dti-1548	520	2	j	j	PROPN
dti-1548	520	3	cancer	cancer	PROPN
dti-1548	520	4	suppl	suppl	PROPN
dti-1548	520	5	.	.	PUNCT
dti-1548	521	1	2007;5(5):444–446	2007;5(5):444–446	NUM
dti-1548	521	2	.	.	NOUN
dti-1548	521	3	67	67	NUM
dti-1548	521	4	.	.	PUNCT
dti-1548	522	1	xu	xu	PROPN
dti-1548	522	2	xr	xr	PROPN
dti-1548	522	3	,	,	PUNCT
dti-1548	522	4	huang	huang	PROPN
dti-1548	522	5	j	j	PROPN
dti-1548	522	6	,	,	PUNCT
dti-1548	522	7	xu	xu	PROPN
dti-1548	522	8	zg	zg	PROPN
dti-1548	522	9	,	,	PUNCT
dti-1548	522	10	qian	qian	PROPN
dti-1548	522	11	bz	bz	PROPN
dti-1548	522	12	,	,	PUNCT
dti-1548	522	13	et	et	PROPN
dti-1548	522	14	al	al	PROPN
dti-1548	522	15	.	.	PROPN
dti-1548	522	16	insight	insight	NOUN
dti-1548	522	17	into	into	ADP
dti-1548	522	18	hepatocellular	hepatocellular	ADJ
dti-1548	522	19	carcinogenesis	carcinogenesis	NOUN
dti-1548	522	20	at	at	ADP
dti-1548	522	21	transcriptome	transcriptome	ADJ
dti-1548	522	22	level	level	NOUN
dti-1548	522	23	by	by	ADP
dti-1548	522	24	comparing	compare	VERB
dti-1548	522	25	gene	gene	NOUN
dti-1548	522	26	expression	expression	NOUN
dti-1548	522	27	profiles	profile	NOUN
dti-1548	522	28	of	of	ADP
dti-1548	522	29	hepatocellular	hepatocellular	ADJ
dti-1548	522	30	carcinoma	carcinoma	NOUN
dti-1548	522	31	with	with	ADP
dti-1548	522	32	those	those	PRON
dti-1548	522	33	of	of	ADP
dti-1548	522	34	corresponding	correspond	VERB
dti-1548	522	35	noncancerous	noncancerous	ADJ
dti-1548	522	36	liver	liver	NOUN
dti-1548	522	37	.	.	PUNCT
dti-1548	523	1	proc	proc	PROPN
dti-1548	523	2	natl	natl	PROPN
dti-1548	523	3	acad	acad	PROPN
dti-1548	523	4	sci	sci	PROPN
dti-1548	523	5	usa	usa	PROPN
dti-1548	523	6	.	.	PROPN
dti-1548	523	7	2001;98(26):15089–15094	2001;98(26):15089–15094	NUM
dti-1548	523	8	.	.	PUNCT
dti-1548	524	1	68	68	NUM
dti-1548	524	2	.	.	X
dti-1548	525	1	boyault	boyault	PROPN
dti-1548	525	2	s	s	PROPN
dti-1548	525	3	,	,	PUNCT
dti-1548	525	4	rickman	rickman	PROPN
dti-1548	525	5	ds	ds	PROPN
dti-1548	525	6	,	,	PUNCT
dti-1548	525	7	de	de	X
dti-1548	525	8	reynies	reynie	NOUN
dti-1548	525	9	a	a	PRON
dti-1548	525	10	,	,	PUNCT
dti-1548	525	11	et	et	PROPN
dti-1548	525	12	al	al	PROPN
dti-1548	525	13	.	.	PUNCT
dti-1548	526	1	transcriptome	transcriptome	ADJ
dti-1548	526	2	classification	classification	NOUN
dti-1548	526	3	of	of	ADP
dti-1548	526	4	hcc	hcc	PROPN
dti-1548	526	5	is	be	AUX
dti-1548	526	6	related	relate	VERB
dti-1548	526	7	to	to	ADP
dti-1548	526	8	gene	gene	NOUN
dti-1548	526	9	alterations	alteration	NOUN
dti-1548	526	10	and	and	CCONJ
dti-1548	526	11	to	to	ADP
dti-1548	526	12	new	new	ADJ
dti-1548	526	13	therapeutic	therapeutic	ADJ
dti-1548	526	14	targets	target	NOUN
dti-1548	526	15	.	.	PUNCT
dti-1548	527	1	hepatology	hepatology	NOUN
dti-1548	527	2	.	.	PUNCT
dti-1548	528	1	2007;45(1):42–52	2007;45(1):42–52	NUM
dti-1548	528	2	.	.	PUNCT
dti-1548	529	1	69	69	NUM
dti-1548	529	2	.	.	PUNCT
dti-1548	530	1	chuma	chuma	PROPN
dti-1548	530	2	m	m	PROPN
dti-1548	530	3	,	,	PUNCT
dti-1548	530	4	sakamoto	sakamoto	PROPN
dti-1548	530	5	m	m	PROPN
dti-1548	530	6	,	,	PUNCT
dti-1548	530	7	yamazaki	yamazaki	PROPN
dti-1548	530	8	k	k	PROPN
dti-1548	530	9	,	,	PUNCT
dti-1548	530	10	et	et	PROPN
dti-1548	530	11	al	al	PROPN
dti-1548	530	12	.	.	PUNCT
dti-1548	531	1	expression	expression	NOUN
dti-1548	531	2	profiling	profiling	NOUN
dti-1548	531	3	in	in	ADP
dti-1548	531	4	multistage	multistage	NOUN
dti-1548	531	5	hepatocarcinogenesis	hepatocarcinogenesis	NOUN
dti-1548	531	6	:	:	PUNCT
dti-1548	531	7	identification	identification	NOUN
dti-1548	531	8	of	of	ADP
dti-1548	531	9	hsp70	hsp70	NOUN
dti-1548	531	10	as	as	ADP
dti-1548	531	11	a	a	DET
dti-1548	531	12	molecular	molecular	ADJ
dti-1548	531	13	marker	marker	NOUN
dti-1548	531	14	of	of	ADP
dti-1548	531	15	early	early	ADJ
dti-1548	531	16	hepatocellular	hepatocellular	ADJ
dti-1548	531	17	carcinoma	carcinoma	NOUN
dti-1548	531	18	.	.	PUNCT
dti-1548	532	1	hepatology	hepatology	NOUN
dti-1548	532	2	.	.	PUNCT
dti-1548	533	1	2003;37(1):198–207	2003;37(1):198–207	X
dti-1548	533	2	.	.	X
dti-1548	534	1	70	70	NUM
dti-1548	534	2	.	.	PUNCT
dti-1548	535	1	makowska	makowska	PROPN
dti-1548	535	2	z	z	PROPN
dti-1548	535	3	,	,	PUNCT
dti-1548	535	4	boldanova	boldanova	PROPN
dti-1548	535	5	t	t	PROPN
dti-1548	535	6	,	,	PUNCT
dti-1548	535	7	adametz	adametz	PROPN
dti-1548	535	8	d	d	PROPN
dti-1548	535	9	,	,	PUNCT
dti-1548	535	10	et	et	PROPN
dti-1548	535	11	al	al	PROPN
dti-1548	535	12	.	.	PUNCT
dti-1548	535	13	gene	gene	NOUN
dti-1548	535	14	expression	expression	NOUN
dti-1548	535	15	analysis	analysis	NOUN
dti-1548	535	16	of	of	ADP
dti-1548	535	17	biopsy	biopsy	NOUN
dti-1548	535	18	samples	sample	NOUN
dti-1548	535	19	reveals	reveal	VERB
dti-1548	535	20	critical	critical	ADJ
dti-1548	535	21	limitations	limitation	NOUN
dti-1548	535	22	of	of	ADP
dti-1548	535	23	transcriptome	transcriptome	NOUN
dti-1548	535	24	-	-	PUNCT
dti-1548	535	25	based	base	VERB
dti-1548	535	26	molecular	molecular	ADJ
dti-1548	535	27	classifications	classification	NOUN
dti-1548	535	28	of	of	ADP
dti-1548	535	29	hepatocellular	hepatocellular	ADJ
dti-1548	535	30	carcinoma	carcinoma	NOUN
dti-1548	535	31	.	.	PUNCT
dti-1548	536	1	j	j	PROPN
dti-1548	536	2	pathol	pathol	VERB
dti-1548	536	3	clin	clin	PROPN
dti-1548	536	4	res	re	NOUN
dti-1548	536	5	.	.	PUNCT
dti-1548	537	1	2016;2(2):80–92	2016;2(2):80–92	NUM
dti-1548	537	2	.	.	PUNCT
dti-1548	538	1	71	71	NUM
dti-1548	538	2	.	.	PUNCT
dti-1548	539	1	waxman	waxman	PROPN
dti-1548	539	2	s	s	PROPN
dti-1548	539	3	,	,	PUNCT
dti-1548	539	4	wurmbach	wurmbach	PROPN
dti-1548	539	5	e.	e.	PROPN
dti-1548	539	6	de	de	PROPN
dti-1548	539	7	-	-	NOUN
dti-1548	539	8	regulation	regulation	NOUN
dti-1548	539	9	of	of	ADP
dti-1548	539	10	common	common	ADJ
dti-1548	539	11	housekeeping	housekeeping	NOUN
dti-1548	539	12	genes	gene	NOUN
dti-1548	539	13	in	in	ADP
dti-1548	539	14	hepatocellular	hepatocellular	ADJ
dti-1548	539	15	carcinoma	carcinoma	NOUN
dti-1548	539	16	.	.	PUNCT
dti-1548	540	1	bmc	bmc	ADJ
dti-1548	540	2	genomics	genomic	NOUN
dti-1548	540	3	.	.	PUNCT
dti-1548	541	1	2007;8:243	2007;8:243	NOUN
dti-1548	541	2	.	.	PUNCT
dti-1548	542	1	72	72	NUM
dti-1548	542	2	.	.	X
dti-1548	542	3	zucman	zucman	NOUN
dti-1548	542	4	-	-	PUNCT
dti-1548	542	5	rossi	rossi	PROPN
dti-1548	542	6	j	j	PROPN
dti-1548	542	7	,	,	PUNCT
dti-1548	542	8	villanueva	villanueva	PROPN
dti-1548	542	9	a	a	PRON
dti-1548	542	10	,	,	PUNCT
dti-1548	542	11	nault	nault	PROPN
dti-1548	542	12	j	j	PROPN
dti-1548	542	13	-	-	PUNCT
dti-1548	542	14	c	c	PROPN
dti-1548	542	15	,	,	PUNCT
dti-1548	542	16	llovet	llovet	PROPN
dti-1548	542	17	jm	jm	PROPN
dti-1548	542	18	.	.	PROPN
dti-1548	543	1	genetic	genetic	ADJ
dti-1548	543	2	landscape	landscape	NOUN
dti-1548	543	3	and	and	CCONJ
dti-1548	543	4	biomarkers	biomarker	NOUN
dti-1548	543	5	of	of	ADP
dti-1548	543	6	hepatocellular	hepatocellular	ADJ
dti-1548	543	7	carcinoma	carcinoma	NOUN
dti-1548	543	8	.	.	PUNCT
dti-1548	544	1	gastroenterology	gastroenterology	NOUN
dti-1548	544	2	.	.	PUNCT
dti-1548	545	1	2015;149(5):1226–1239	2015;149(5):1226–1239	NUM
dti-1548	545	2	.	.	PUNCT
dti-1548	545	3	e1224	e1224	PROPN
dti-1548	545	4	.	.	PUNCT