id	sid	tid	token	lemma	pos
dti-2185	1	1	dti	dti	PROPN
dti-2185	1	2	©	©	PROPN
dti-2185	1	3	2020	2020	NUM
dti-2185	1	4	the	the	DET
dti-2185	1	5	authors	author	NOUN
dti-2185	1	6	.	.	PUNCT
dti-2185	2	1	this	this	DET
dti-2185	2	2	article	article	NOUN
dti-2185	2	3	is	be	AUX
dti-2185	2	4	published	publish	VERB
dti-2185	2	5	by	by	ADP
dti-2185	2	6	aboutscience	aboutscience	NOUN
dti-2185	2	7	and	and	CCONJ
dti-2185	2	8	licensed	license	VERB
dti-2185	2	9	under	under	ADP
dti-2185	2	10	creative	creative	ADJ
dti-2185	2	11	commons	common	NOUN
dti-2185	2	12	attribution	attribution	NOUN
dti-2185	2	13	-	-	PUNCT
dti-2185	2	14	noncommercial	noncommercial	ADJ
dti-2185	2	15	4.0	4.0	NUM
dti-2185	2	16	international	international	NOUN
dti-2185	2	17	(	(	PUNCT
dti-2185	2	18	cc	cc	NOUN
dti-2185	2	19	by	by	ADP
dti-2185	2	20	-	-	PUNCT
dti-2185	2	21	nc	nc	PROPN
dti-2185	2	22	4.0	4.0	NUM
dti-2185	2	23	)	)	PUNCT
dti-2185	2	24	.	.	PUNCT
dti-2185	3	1	any	any	DET
dti-2185	3	2	commercial	commercial	ADJ
dti-2185	3	3	use	use	NOUN
dti-2185	3	4	is	be	AUX
dti-2185	3	5	not	not	PART
dti-2185	3	6	permitted	permit	VERB
dti-2185	3	7	and	and	CCONJ
dti-2185	3	8	is	be	AUX
dti-2185	3	9	subject	subject	ADJ
dti-2185	3	10	to	to	ADP
dti-2185	3	11	publisher	publisher	NOUN
dti-2185	3	12	’s	’s	PART
dti-2185	3	13	permissions	permission	NOUN
dti-2185	3	14	.	.	PUNCT
dti-2185	4	1	full	full	ADJ
dti-2185	4	2	information	information	NOUN
dti-2185	4	3	is	be	AUX
dti-2185	4	4	available	available	ADJ
dti-2185	4	5	at	at	ADP
dti-2185	4	6	www.aboutscience.eu	www.aboutscience.eu	PROPN
dti-2185	4	7	issn	issn	PROPN
dti-2185	4	8	1177	1177	NUM
dti-2185	4	9	-	-	SYM
dti-2185	4	10	3928	3928	NUM
dti-2185	4	11	drug	drug	NOUN
dti-2185	4	12	target	target	NOUN
dti-2185	4	13	insights	insight	NOUN
dti-2185	4	14	2020	2020	NUM
dti-2185	4	15	;	;	PUNCT
dti-2185	4	16	14	14	NUM
dti-2185	4	17	:	:	SYM
dti-2185	4	18	34	34	NUM
dti-2185	4	19	-	-	SYM
dti-2185	4	20	47	47	NUM
dti-2185	4	21	review	review	NOUN
dti-2185	4	22	doi	doi	NOUN
dti-2185	4	23	:	:	PUNCT
dti-2185	4	24	10.33393	10.33393	NUM
dti-2185	4	25	/	/	SYM
dti-2185	4	26	dti.2020.2185	dti.2020.2185	PRON
dti-2185	4	27	interaction	interaction	NOUN
dti-2185	4	28	of	of	ADP
dti-2185	4	29	drugs	drug	NOUN
dti-2185	4	30	with	with	ADP
dti-2185	4	31	lipid	lipid	NOUN
dti-2185	4	32	raft	raft	NOUN
dti-2185	4	33	membrane	membrane	NOUN
dti-2185	4	34	domains	domain	NOUN
dti-2185	4	35	as	as	ADP
dti-2185	4	36	a	a	DET
dti-2185	4	37	possible	possible	ADJ
dti-2185	4	38	target	target	NOUN
dti-2185	4	39	hironori	hironori	NOUN
dti-2185	4	40	tsuchiya1	tsuchiya1	NOUN
dti-2185	4	41	,	,	PUNCT
dti-2185	4	42	maki	maki	PROPN
dti-2185	4	43	mizogami2	mizogami2	PROPN
dti-2185	5	1	1asahi	1asahi	NUM
dti-2185	5	2	university	university	NOUN
dti-2185	5	3	school	school	NOUN
dti-2185	5	4	of	of	ADP
dti-2185	5	5	dentistry	dentistry	NOUN
dti-2185	5	6	,	,	PUNCT
dti-2185	5	7	mizuho	mizuho	PROPN
dti-2185	5	8	,	,	PUNCT
dti-2185	5	9	gifu	gifu	PROPN
dti-2185	5	10	japan	japan	PROPN
dti-2185	5	11	2department	2department	PROPN
dti-2185	5	12	of	of	ADP
dti-2185	5	13	anesthesiology	anesthesiology	NOUN
dti-2185	5	14	,	,	PUNCT
dti-2185	5	15	kizawa	kizawa	PROPN
dti-2185	5	16	memorial	memorial	ADJ
dti-2185	5	17	hospital	hospital	NOUN
dti-2185	5	18	,	,	PUNCT
dti-2185	5	19	minokamo	minokamo	PROPN
dti-2185	5	20	,	,	PUNCT
dti-2185	5	21	gifu	gifu	PROPN
dti-2185	5	22	japan	japan	PROPN
dti-2185	5	23	abstract	abstract	PROPN
dti-2185	5	24	introduction	introduction	NOUN
dti-2185	5	25	:	:	PUNCT
dti-2185	5	26	plasma	plasma	NOUN
dti-2185	5	27	membranes	membrane	NOUN
dti-2185	5	28	are	be	AUX
dti-2185	5	29	not	not	PART
dti-2185	5	30	the	the	DET
dti-2185	5	31	homogeneous	homogeneous	ADJ
dti-2185	5	32	bilayers	bilayer	NOUN
dti-2185	5	33	of	of	ADP
dti-2185	5	34	uniformly	uniformly	ADV
dti-2185	5	35	distributed	distribute	VERB
dti-2185	5	36	lipids	lipid	NOUN
dti-2185	5	37	but	but	CCONJ
dti-2185	5	38	the	the	DET
dti-2185	5	39	lipid	lipid	NOUN
dti-2185	5	40	complex	complex	NOUN
dti-2185	5	41	with	with	ADP
dti-2185	5	42	laterally	laterally	ADV
dti-2185	5	43	separated	separate	VERB
dti-2185	5	44	lipid	lipid	NOUN
dti-2185	5	45	raft	raft	NOUN
dti-2185	5	46	membrane	membrane	NOUN
dti-2185	5	47	domains	domain	NOUN
dti-2185	5	48	,	,	PUNCT
dti-2185	5	49	which	which	PRON
dti-2185	5	50	provide	provide	VERB
dti-2185	5	51	receptor	receptor	NOUN
dti-2185	5	52	,	,	PUNCT
dti-2185	5	53	ion	ion	NOUN
dti-2185	5	54	channel	channel	NOUN
dti-2185	5	55	and	and	CCONJ
dti-2185	5	56	enzyme	enzyme	NOUN
dti-2185	5	57	proteins	protein	NOUN
dti-2185	5	58	with	with	ADP
dti-2185	5	59	a	a	DET
dti-2185	5	60	platform	platform	NOUN
dti-2185	5	61	.	.	PUNCT
dti-2185	6	1	the	the	DET
dti-2185	6	2	aim	aim	NOUN
dti-2185	6	3	of	of	ADP
dti-2185	6	4	this	this	DET
dti-2185	6	5	article	article	NOUN
dti-2185	6	6	is	be	AUX
dti-2185	6	7	to	to	PART
dti-2185	6	8	review	review	VERB
dti-2185	6	9	the	the	DET
dti-2185	6	10	mechanistic	mechanistic	ADJ
dti-2185	6	11	interaction	interaction	NOUN
dti-2185	6	12	of	of	ADP
dti-2185	6	13	drugs	drug	NOUN
dti-2185	6	14	with	with	ADP
dti-2185	6	15	membrane	membrane	NOUN
dti-2185	6	16	lipid	lipid	NOUN
dti-2185	6	17	rafts	raft	NOUN
dti-2185	6	18	and	and	CCONJ
dti-2185	6	19	address	address	VERB
dti-2185	6	20	the	the	DET
dti-2185	6	21	question	question	NOUN
dti-2185	6	22	whether	whether	SCONJ
dti-2185	6	23	drugs	drug	NOUN
dti-2185	6	24	induce	induce	VERB
dti-2185	6	25	physicochemical	physicochemical	ADJ
dti-2185	6	26	changes	change	NOUN
dti-2185	6	27	in	in	ADP
dti-2185	6	28	raft	raft	NOUN
dti-2185	6	29	-	-	PUNCT
dti-2185	6	30	constituting	constitute	VERB
dti-2185	6	31	and	and	CCONJ
dti-2185	6	32	raftsurrounding	raftsurrounde	VERB
dti-2185	6	33	membranes	membrane	NOUN
dti-2185	6	34	.	.	PUNCT
dti-2185	7	1	methods	method	NOUN
dti-2185	7	2	:	:	PUNCT
dti-2185	7	3	literature	literature	NOUN
dti-2185	7	4	searches	search	NOUN
dti-2185	7	5	of	of	ADP
dti-2185	7	6	pubmed	pubmed	PROPN
dti-2185	7	7	/	/	SYM
dti-2185	7	8	medline	medline	PROPN
dti-2185	7	9	and	and	CCONJ
dti-2185	7	10	google	google	PROPN
dti-2185	7	11	scholar	scholar	NOUN
dti-2185	7	12	databases	database	NOUN
dti-2185	7	13	from	from	ADP
dti-2185	7	14	2000	2000	NUM
dti-2185	7	15	to	to	ADP
dti-2185	7	16	2020	2020	NUM
dti-2185	7	17	were	be	AUX
dti-2185	7	18	conducted	conduct	VERB
dti-2185	7	19	to	to	PART
dti-2185	7	20	include	include	VERB
dti-2185	7	21	articles	article	NOUN
dti-2185	7	22	published	publish	VERB
dti-2185	7	23	in	in	ADP
dti-2185	7	24	english	english	PROPN
dti-2185	7	25	in	in	ADP
dti-2185	7	26	internationally	internationally	ADV
dti-2185	7	27	recognized	recognize	VERB
dti-2185	7	28	journals	journal	NOUN
dti-2185	7	29	.	.	PUNCT
dti-2185	8	1	collected	collect	VERB
dti-2185	8	2	articles	article	NOUN
dti-2185	8	3	were	be	AUX
dti-2185	8	4	independently	independently	ADV
dti-2185	8	5	reviewed	review	VERB
dti-2185	8	6	by	by	ADP
dti-2185	8	7	title	title	NOUN
dti-2185	8	8	,	,	PUNCT
dti-2185	8	9	abstract	abstract	ADJ
dti-2185	8	10	and	and	CCONJ
dti-2185	8	11	text	text	NOUN
dti-2185	8	12	for	for	ADP
dti-2185	8	13	relevance	relevance	NOUN
dti-2185	8	14	.	.	PUNCT
dti-2185	9	1	results	result	NOUN
dti-2185	9	2	:	:	PUNCT
dti-2185	9	3	the	the	DET
dti-2185	9	4	literature	literature	NOUN
dti-2185	9	5	search	search	NOUN
dti-2185	9	6	indicated	indicate	VERB
dti-2185	9	7	that	that	SCONJ
dti-2185	9	8	pharmacologically	pharmacologically	ADV
dti-2185	9	9	diverse	diverse	ADJ
dti-2185	9	10	drugs	drug	NOUN
dti-2185	9	11	interact	interact	VERB
dti-2185	9	12	with	with	ADP
dti-2185	9	13	raft	raft	NOUN
dti-2185	9	14	model	model	NOUN
dti-2185	9	15	membranes	membrane	NOUN
dti-2185	9	16	and	and	CCONJ
dti-2185	9	17	cellular	cellular	ADJ
dti-2185	9	18	membrane	membrane	NOUN
dti-2185	9	19	lipid	lipid	NOUN
dti-2185	9	20	rafts	raft	NOUN
dti-2185	9	21	.	.	PUNCT
dti-2185	10	1	they	they	PRON
dti-2185	10	2	could	could	AUX
dti-2185	10	3	physicochemically	physicochemically	ADV
dti-2185	10	4	modify	modify	VERB
dti-2185	10	5	functional	functional	ADJ
dti-2185	10	6	protein	protein	NOUN
dti-2185	10	7	-	-	PUNCT
dti-2185	10	8	localizing	localize	VERB
dti-2185	10	9	membrane	membrane	NOUN
dti-2185	10	10	lipid	lipid	NOUN
dti-2185	10	11	rafts	raft	NOUN
dti-2185	10	12	and	and	CCONJ
dti-2185	10	13	the	the	DET
dti-2185	10	14	membranes	membrane	NOUN
dti-2185	10	15	surrounding	surround	VERB
dti-2185	10	16	such	such	ADJ
dti-2185	10	17	domains	domain	NOUN
dti-2185	10	18	,	,	PUNCT
dti-2185	10	19	affecting	affect	VERB
dti-2185	10	20	the	the	DET
dti-2185	10	21	raft	raft	NOUN
dti-2185	10	22	organizational	organizational	ADJ
dti-2185	10	23	integrity	integrity	NOUN
dti-2185	10	24	with	with	ADP
dti-2185	10	25	the	the	DET
dti-2185	10	26	resultant	resultant	NOUN
dti-2185	10	27	exhibition	exhibition	NOUN
dti-2185	10	28	of	of	ADP
dti-2185	10	29	pharmacological	pharmacological	ADJ
dti-2185	10	30	activity	activity	NOUN
dti-2185	10	31	.	.	PUNCT
dti-2185	11	1	raft	raft	NOUN
dti-2185	11	2	-	-	PUNCT
dti-2185	11	3	acting	act	VERB
dti-2185	11	4	drugs	drug	NOUN
dti-2185	11	5	were	be	AUX
dti-2185	11	6	characterized	characterize	VERB
dti-2185	11	7	as	as	ADP
dti-2185	11	8	ones	one	NOUN
dti-2185	11	9	to	to	PART
dti-2185	11	10	decrease	decrease	VERB
dti-2185	11	11	membrane	membrane	ADJ
dti-2185	11	12	fluidity	fluidity	NOUN
dti-2185	11	13	,	,	PUNCT
dti-2185	11	14	induce	induce	VERB
dti-2185	11	15	liquid	liquid	NOUN
dti-2185	11	16	-	-	PUNCT
dti-2185	11	17	ordered	order	VERB
dti-2185	11	18	phase	phase	NOUN
dti-2185	11	19	or	or	CCONJ
dti-2185	11	20	order	order	VERB
dti-2185	11	21	plasma	plasma	NOUN
dti-2185	11	22	membranes	membrane	NOUN
dti-2185	11	23	,	,	PUNCT
dti-2185	11	24	leading	lead	VERB
dti-2185	11	25	to	to	ADP
dti-2185	11	26	lipid	lipid	NOUN
dti-2185	11	27	raft	raft	NOUN
dti-2185	11	28	formation	formation	NOUN
dti-2185	11	29	;	;	PUNCT
dti-2185	11	30	and	and	CCONJ
dti-2185	11	31	ones	one	NOUN
dti-2185	11	32	to	to	PART
dti-2185	11	33	increase	increase	VERB
dti-2185	11	34	membrane	membrane	ADJ
dti-2185	11	35	fluidity	fluidity	NOUN
dti-2185	11	36	,	,	PUNCT
dti-2185	11	37	induce	induce	VERB
dti-2185	11	38	liquid	liquid	NOUN
dti-2185	11	39	-	-	PUNCT
dti-2185	11	40	disordered	disorder	VERB
dti-2185	11	41	phase	phase	NOUN
dti-2185	11	42	or	or	CCONJ
dti-2185	11	43	reduce	reduce	VERB
dti-2185	11	44	phase	phase	NOUN
dti-2185	11	45	transition	transition	NOUN
dti-2185	11	46	temperature	temperature	NOUN
dti-2185	11	47	,	,	PUNCT
dti-2185	11	48	leading	lead	VERB
dti-2185	11	49	to	to	ADP
dti-2185	11	50	lipid	lipid	NOUN
dti-2185	11	51	raft	raft	NOUN
dti-2185	11	52	disruption	disruption	NOUN
dti-2185	11	53	.	.	PUNCT
dti-2185	12	1	conclusion	conclusion	NOUN
dti-2185	12	2	:	:	PUNCT
dti-2185	12	3	targeting	target	VERB
dti-2185	12	4	lipid	lipid	NOUN
dti-2185	12	5	raft	raft	NOUN
dti-2185	12	6	membrane	membrane	NOUN
dti-2185	12	7	domains	domain	NOUN
dti-2185	12	8	would	would	AUX
dti-2185	12	9	open	open	VERB
dti-2185	12	10	a	a	DET
dti-2185	12	11	new	new	ADJ
dti-2185	12	12	way	way	NOUN
dti-2185	12	13	for	for	ADP
dti-2185	12	14	drug	drug	NOUN
dti-2185	12	15	design	design	NOUN
dti-2185	12	16	and	and	CCONJ
dti-2185	12	17	development	development	NOUN
dti-2185	12	18	.	.	PUNCT
dti-2185	13	1	since	since	SCONJ
dti-2185	13	2	angiotensin	angiotensin	NOUN
dti-2185	13	3	-	-	PUNCT
dti-2185	13	4	converting	convert	VERB
dti-2185	13	5	enzyme	enzyme	NOUN
dti-2185	13	6	2	2	NUM
dti-2185	13	7	receptors	receptor	NOUN
dti-2185	13	8	which	which	PRON
dti-2185	13	9	are	be	AUX
dti-2185	13	10	a	a	DET
dti-2185	13	11	cell	cell	NOUN
dti-2185	13	12	-	-	PUNCT
dti-2185	13	13	specific	specific	ADJ
dti-2185	13	14	target	target	NOUN
dti-2185	13	15	of	of	ADP
dti-2185	13	16	and	and	CCONJ
dti-2185	13	17	responsible	responsible	ADJ
dti-2185	13	18	for	for	ADP
dti-2185	13	19	the	the	DET
dti-2185	13	20	cellular	cellular	ADJ
dti-2185	13	21	entry	entry	NOUN
dti-2185	13	22	of	of	ADP
dti-2185	13	23	novel	novel	ADJ
dti-2185	13	24	coronavirus	coronavirus	NOUN
dti-2185	13	25	are	be	AUX
dti-2185	13	26	localized	localize	VERB
dti-2185	13	27	in	in	ADP
dti-2185	13	28	lipid	lipid	ADJ
dti-2185	13	29	rafts	raft	NOUN
dti-2185	13	30	,	,	PUNCT
dti-2185	13	31	agents	agent	NOUN
dti-2185	13	32	that	that	PRON
dti-2185	13	33	specifically	specifically	ADV
dti-2185	13	34	disrupt	disrupt	VERB
dti-2185	13	35	the	the	DET
dti-2185	13	36	relevant	relevant	ADJ
dti-2185	13	37	rafts	raft	NOUN
dti-2185	13	38	may	may	AUX
dti-2185	13	39	be	be	AUX
dti-2185	13	40	a	a	DET
dti-2185	13	41	drug	drug	NOUN
dti-2185	13	42	against	against	ADP
dti-2185	13	43	coronavirus	coronavirus	NOUN
dti-2185	13	44	disease	disease	NOUN
dti-2185	13	45	2019	2019	NUM
dti-2185	13	46	.	.	PUNCT
dti-2185	14	1	keywords	keyword	NOUN
dti-2185	14	2	:	:	PUNCT
dti-2185	14	3	drug	drug	NOUN
dti-2185	14	4	target	target	NOUN
dti-2185	14	5	,	,	PUNCT
dti-2185	14	6	fluidity	fluidity	NOUN
dti-2185	14	7	,	,	PUNCT
dti-2185	14	8	lipid	lipid	NOUN
dti-2185	14	9	raft	raft	NOUN
dti-2185	14	10	,	,	PUNCT
dti-2185	14	11	membrane	membrane	NOUN
dti-2185	14	12	domain	domain	NOUN
dti-2185	14	13	,	,	PUNCT
dti-2185	14	14	membrane	membrane	NOUN
dti-2185	14	15	interaction	interaction	NOUN
dti-2185	14	16	received	receive	VERB
dti-2185	14	17	:	:	PUNCT
dti-2185	14	18	september	september	PROPN
dti-2185	14	19	17	17	NUM
dti-2185	14	20	,	,	PUNCT
dti-2185	14	21	2020	2020	NUM
dti-2185	14	22	accepted	accept	VERB
dti-2185	14	23	:	:	PUNCT
dti-2185	14	24	november	november	PROPN
dti-2185	14	25	11	11	NUM
dti-2185	14	26	,	,	PUNCT
dti-2185	14	27	2020	2020	NUM
dti-2185	14	28	published	publish	VERB
dti-2185	14	29	online	online	ADV
dti-2185	14	30	:	:	PUNCT
dti-2185	14	31	december	december	PROPN
dti-2185	14	32	22	22	NUM
dti-2185	14	33	,	,	PUNCT
dti-2185	14	34	2020	2020	NUM
dti-2185	14	35	corresponding	correspond	VERB
dti-2185	14	36	author	author	NOUN
dti-2185	14	37	:	:	PUNCT
dti-2185	14	38	hironori	hironori	PROPN
dti-2185	14	39	tsuchiya	tsuchiya	PROPN
dti-2185	14	40	asahi	asahi	PROPN
dti-2185	14	41	university	university	PROPN
dti-2185	14	42	school	school	NOUN
dti-2185	14	43	of	of	ADP
dti-2185	14	44	dentistry	dentistry	PROPN
dti-2185	14	45	1851	1851	NUM
dti-2185	14	46	hozumi	hozumi	PROPN
dti-2185	14	47	,	,	PUNCT
dti-2185	14	48	mizuho	mizuho	PROPN
dti-2185	14	49	,	,	PUNCT
dti-2185	14	50	gifu	gifu	VERB
dti-2185	14	51	501	501	NUM
dti-2185	14	52	-	-	SYM
dti-2185	14	53	0296	0296	NUM
dti-2185	14	54	japan	japan	PROPN
dti-2185	14	55	tsuchi-hiroki16@dent.asahi-u.ac.jp	tsuchi-hiroki16@dent.asahi-u.ac.jp	PROPN
dti-2185	14	56	of	of	ADP
dti-2185	14	57	the	the	DET
dti-2185	14	58	membrane	membrane	NOUN
dti-2185	14	59	structures	structure	NOUN
dti-2185	14	60	(	(	PUNCT
dti-2185	14	61	2	2	NUM
dti-2185	14	62	)	)	PUNCT
dti-2185	14	63	,	,	PUNCT
dti-2185	14	64	whereas	whereas	SCONJ
dti-2185	14	65	caveolae	caveolae	NOUN
dti-2185	14	66	are	be	AUX
dti-2185	14	67	a	a	DET
dti-2185	14	68	subset	subset	NOUN
dti-2185	14	69	of	of	ADP
dti-2185	14	70	lipid	lipid	ADJ
dti-2185	14	71	rafts	raft	NOUN
dti-2185	14	72	and	and	CCONJ
dti-2185	14	73	organizationally	organizationally	ADV
dti-2185	14	74	maintained	maintain	VERB
dti-2185	14	75	by	by	ADP
dti-2185	14	76	characteristic	characteristic	ADJ
dti-2185	14	77	protein	protein	NOUN
dti-2185	14	78	caveolins	caveolin	NOUN
dti-2185	14	79	(	(	PUNCT
dti-2185	14	80	3	3	NUM
dti-2185	14	81	)	)	PUNCT
dti-2185	14	82	.	.	PUNCT
dti-2185	15	1	lipid	lipid	NOUN
dti-2185	15	2	rafts	raft	NOUN
dti-2185	15	3	in	in	ADP
dti-2185	15	4	a	a	DET
dti-2185	15	5	liquid	liquid	NOUN
dti-2185	15	6	-	-	PUNCT
dti-2185	15	7	ordered	order	VERB
dti-2185	15	8	(	(	PUNCT
dti-2185	15	9	lo	lo	NOUN
dti-2185	15	10	)	)	PUNCT
dti-2185	15	11	phase	phase	NOUN
dti-2185	15	12	coexist	coexist	VERB
dti-2185	15	13	with	with	ADP
dti-2185	15	14	the	the	DET
dti-2185	15	15	bulk	bulk	NOUN
dti-2185	15	16	of	of	ADP
dti-2185	15	17	membranes	membrane	NOUN
dti-2185	15	18	in	in	ADP
dti-2185	15	19	a	a	DET
dti-2185	15	20	liquid	liquid	ADJ
dti-2185	15	21	disordered	disorder	VERB
dti-2185	15	22	(	(	PUNCT
dti-2185	15	23	ld	ld	NOUN
dti-2185	15	24	)	)	PUNCT
dti-2185	15	25	phase	phase	NOUN
dti-2185	15	26	(	(	PUNCT
dti-2185	15	27	4	4	NUM
dti-2185	15	28	)	)	PUNCT
dti-2185	15	29	.	.	PUNCT
dti-2185	16	1	lipid	lipid	NOUN
dti-2185	16	2	raft	raft	NOUN
dti-2185	16	3	membrane	membrane	NOUN
dti-2185	16	4	domains	domain	NOUN
dti-2185	16	5	play	play	VERB
dti-2185	16	6	an	an	DET
dti-2185	16	7	important	important	ADJ
dti-2185	16	8	role	role	NOUN
dti-2185	16	9	in	in	ADP
dti-2185	16	10	cellular	cellular	ADJ
dti-2185	16	11	signal	signal	NOUN
dti-2185	16	12	transduction	transduction	NOUN
dti-2185	16	13	and	and	CCONJ
dti-2185	16	14	trafficking	traffic	VERB
dti-2185	16	15	by	by	ADP
dti-2185	16	16	compartmentalizing	compartmentalize	VERB
dti-2185	16	17	membranes	membrane	NOUN
dti-2185	16	18	and	and	CCONJ
dti-2185	16	19	providing	provide	VERB
dti-2185	16	20	functional	functional	ADJ
dti-2185	16	21	membrane	membrane	NOUN
dti-2185	16	22	proteins	protein	NOUN
dti-2185	16	23	with	with	ADP
dti-2185	16	24	a	a	DET
dti-2185	16	25	platform	platform	NOUN
dti-2185	16	26	(	(	PUNCT
dti-2185	16	27	4	4	NUM
dti-2185	16	28	-	-	SYM
dti-2185	16	29	7	7	NUM
dti-2185	16	30	)	)	PUNCT
dti-2185	16	31	.	.	PUNCT
dti-2185	17	1	pharmacologically	pharmacologically	ADV
dti-2185	17	2	relevant	relevant	ADJ
dti-2185	17	3	receptors	receptor	NOUN
dti-2185	17	4	,	,	PUNCT
dti-2185	17	5	ion	ion	NOUN
dti-2185	17	6	channels	channel	NOUN
dti-2185	17	7	and	and	CCONJ
dti-2185	17	8	enzymes	enzyme	NOUN
dti-2185	17	9	are	be	AUX
dti-2185	17	10	localized	localize	VERB
dti-2185	17	11	or	or	CCONJ
dti-2185	17	12	cluster	cluster	NOUN
dti-2185	17	13	in	in	ADP
dti-2185	17	14	membrane	membrane	NOUN
dti-2185	17	15	lipid	lipid	NOUN
dti-2185	17	16	rafts	raft	NOUN
dti-2185	17	17	and	and	CCONJ
dti-2185	17	18	caveolae	caveolae	NOUN
dti-2185	17	19	(	(	PUNCT
dti-2185	17	20	8	8	NUM
dti-2185	17	21	-	-	SYM
dti-2185	17	22	11	11	NUM
dti-2185	17	23	)	)	PUNCT
dti-2185	17	24	.	.	PUNCT
dti-2185	18	1	given	give	VERB
dti-2185	18	2	the	the	DET
dti-2185	18	3	localization	localization	NOUN
dti-2185	18	4	of	of	ADP
dti-2185	18	5	receptors	receptor	NOUN
dti-2185	18	6	,	,	PUNCT
dti-2185	18	7	ion	ion	NOUN
dti-2185	18	8	channels	channel	NOUN
dti-2185	18	9	and	and	CCONJ
dti-2185	18	10	enzymes	enzyme	NOUN
dti-2185	18	11	in	in	ADP
dti-2185	18	12	membrane	membrane	NOUN
dti-2185	18	13	lipid	lipid	NOUN
dti-2185	18	14	rafts	raft	NOUN
dti-2185	18	15	,	,	PUNCT
dti-2185	18	16	the	the	DET
dti-2185	18	17	mode	mode	NOUN
dti-2185	18	18	of	of	ADP
dti-2185	18	19	drug	drug	NOUN
dti-2185	18	20	action	action	NOUN
dti-2185	18	21	is	be	AUX
dti-2185	18	22	first	first	ADV
dti-2185	18	23	interpretable	interpretable	ADJ
dti-2185	18	24	in	in	ADP
dti-2185	18	25	a	a	DET
dti-2185	18	26	simple	simple	ADJ
dti-2185	18	27	manner	manner	NOUN
dti-2185	18	28	of	of	ADP
dti-2185	18	29	receptor	receptor	NOUN
dti-2185	18	30	/	/	SYM
dti-2185	18	31	channel/	channel/	NUM
dti-2185	18	32	enzyme	enzyme	NOUN
dti-2185	18	33	and	and	CCONJ
dti-2185	18	34	ligand	ligand	NOUN
dti-2185	18	35	interaction	interaction	NOUN
dti-2185	18	36	as	as	SCONJ
dti-2185	18	37	known	know	VERB
dti-2185	18	38	in	in	ADP
dti-2185	18	39	the	the	DET
dti-2185	18	40	conventional	conventional	ADJ
dti-2185	18	41	mechanistic	mechanistic	ADJ
dti-2185	18	42	theory	theory	NOUN
dti-2185	18	43	.	.	PUNCT
dti-2185	19	1	the	the	DET
dti-2185	19	2	second	second	ADJ
dti-2185	19	3	possibility	possibility	NOUN
dti-2185	19	4	is	be	AUX
dti-2185	19	5	that	that	SCONJ
dti-2185	19	6	drugs	drug	NOUN
dti-2185	19	7	may	may	AUX
dti-2185	19	8	act	act	VERB
dti-2185	19	9	on	on	ADP
dti-2185	19	10	membrane	membrane	NOUN
dti-2185	19	11	lipids	lipid	NOUN
dti-2185	19	12	to	to	PART
dti-2185	19	13	affect	affect	VERB
dti-2185	19	14	the	the	DET
dti-2185	19	15	organizational	organizational	ADJ
dti-2185	19	16	integrity	integrity	NOUN
dti-2185	19	17	of	of	ADP
dti-2185	19	18	lipid	lipid	ADJ
dti-2185	19	19	rafts	raft	NOUN
dti-2185	19	20	,	,	PUNCT
dti-2185	19	21	resulting	result	VERB
dti-2185	19	22	in	in	ADP
dti-2185	19	23	modulation	modulation	NOUN
dti-2185	19	24	of	of	ADP
dti-2185	19	25	the	the	DET
dti-2185	19	26	activity	activity	NOUN
dti-2185	19	27	of	of	ADP
dti-2185	19	28	receptors	receptor	NOUN
dti-2185	19	29	,	,	PUNCT
dti-2185	19	30	ion	ion	NOUN
dti-2185	19	31	channels	channel	NOUN
dti-2185	19	32	and	and	CCONJ
dti-2185	19	33	enzymes	enzyme	NOUN
dti-2185	19	34	embedded	embed	VERB
dti-2185	19	35	in	in	ADP
dti-2185	19	36	membrane	membrane	NOUN
dti-2185	19	37	domains	domain	NOUN
dti-2185	19	38	.	.	PUNCT
dti-2185	20	1	it	it	PRON
dti-2185	20	2	is	be	AUX
dti-2185	20	3	of	of	ADP
dti-2185	20	4	much	much	ADJ
dti-2185	20	5	interest	interest	NOUN
dti-2185	20	6	to	to	PART
dti-2185	20	7	know	know	VERB
dti-2185	20	8	whether	whether	SCONJ
dti-2185	20	9	drugs	drug	NOUN
dti-2185	20	10	interact	interact	VERB
dti-2185	20	11	introduction	introduction	NOUN
dti-2185	20	12	since	since	SCONJ
dti-2185	20	13	singer	singer	NOUN
dti-2185	20	14	and	and	CCONJ
dti-2185	20	15	nicolson	nicolson	PROPN
dti-2185	20	16	proposed	propose	VERB
dti-2185	20	17	a	a	DET
dti-2185	20	18	fluid	fluid	ADJ
dti-2185	20	19	mosaic	mosaic	ADJ
dti-2185	20	20	model	model	NOUN
dti-2185	20	21	,	,	PUNCT
dti-2185	20	22	the	the	DET
dti-2185	20	23	concept	concept	NOUN
dti-2185	20	24	of	of	ADP
dti-2185	20	25	membrane	membrane	NOUN
dti-2185	20	26	organization	organization	NOUN
dti-2185	20	27	has	have	AUX
dti-2185	20	28	progressively	progressively	ADV
dti-2185	20	29	changed	change	VERB
dti-2185	20	30	,	,	PUNCT
dti-2185	20	31	that	that	ADV
dti-2185	20	32	is	is	ADV
dti-2185	20	33	,	,	PUNCT
dti-2185	20	34	plasma	plasma	NOUN
dti-2185	20	35	membranes	membrane	NOUN
dti-2185	20	36	are	be	AUX
dti-2185	20	37	not	not	PART
dti-2185	20	38	the	the	DET
dti-2185	20	39	homogeneous	homogeneous	ADJ
dti-2185	20	40	bilayers	bilayer	NOUN
dti-2185	20	41	of	of	ADP
dti-2185	20	42	uniformly	uniformly	ADV
dti-2185	20	43	distributed	distribute	VERB
dti-2185	20	44	lipids	lipid	NOUN
dti-2185	20	45	but	but	CCONJ
dti-2185	20	46	the	the	DET
dti-2185	20	47	lipid	lipid	NOUN
dti-2185	20	48	complex	complex	NOUN
dti-2185	20	49	with	with	ADP
dti-2185	20	50	laterally	laterally	ADV
dti-2185	20	51	separated	separate	VERB
dti-2185	20	52	membrane	membrane	NOUN
dti-2185	20	53	domains	domain	NOUN
dti-2185	20	54	such	such	ADJ
dti-2185	20	55	as	as	ADP
dti-2185	20	56	lipid	lipid	ADJ
dti-2185	20	57	rafts	raft	NOUN
dti-2185	20	58	and	and	CCONJ
dti-2185	20	59	caveolae	caveolae	NOUN
dti-2185	20	60	(	(	PUNCT
dti-2185	20	61	1	1	NUM
dti-2185	20	62	)	)	PUNCT
dti-2185	20	63	.	.	PUNCT
dti-2185	21	1	lipid	lipid	NOUN
dti-2185	21	2	rafts	raft	NOUN
dti-2185	21	3	are	be	AUX
dti-2185	21	4	small	small	ADJ
dti-2185	21	5	(	(	PUNCT
dti-2185	21	6	10	10	NUM
dti-2185	21	7	-	-	SYM
dti-2185	21	8	200	200	NUM
dti-2185	21	9	nm	nm	NOUN
dti-2185	21	10	)	)	PUNCT
dti-2185	21	11	,	,	PUNCT
dti-2185	21	12	heterogeneous	heterogeneous	ADJ
dti-2185	21	13	,	,	PUNCT
dti-2185	21	14	dynamic	dynamic	ADJ
dti-2185	21	15	,	,	PUNCT
dti-2185	21	16	and	and	CCONJ
dti-2185	21	17	cholesteroland	cholesteroland	VERB
dti-2185	21	18	sphingolipidenriched	sphingolipidenriche	VERB
dti-2185	21	19	membrane	membrane	NOUN
dti-2185	21	20	domains	domain	NOUN
dti-2185	21	21	that	that	PRON
dti-2185	21	22	are	be	AUX
dti-2185	21	23	distinct	distinct	ADJ
dti-2185	21	24	from	from	ADP
dti-2185	21	25	the	the	DET
dti-2185	21	26	rest	rest	NOUN
dti-2185	21	27	tsuchiya	tsuchiya	PROPN
dti-2185	21	28	and	and	CCONJ
dti-2185	21	29	mizogami	mizogami	PROPN
dti-2185	21	30	35	35	NUM
dti-2185	21	31	©	©	PROPN
dti-2185	21	32	2020	2020	NUM
dti-2185	21	33	the	the	DET
dti-2185	21	34	authors	author	NOUN
dti-2185	21	35	.	.	PUNCT
dti-2185	22	1	published	publish	VERB
dti-2185	22	2	by	by	ADP
dti-2185	22	3	aboutscience	aboutscience	NOUN
dti-2185	22	4	preferentially	preferentially	ADV
dti-2185	22	5	with	with	ADP
dti-2185	22	6	lipid	lipid	ADJ
dti-2185	22	7	rafts	raft	NOUN
dti-2185	22	8	compared	compare	VERB
dti-2185	22	9	with	with	ADP
dti-2185	22	10	non	non	ADJ
dti-2185	22	11	-	-	ADJ
dti-2185	22	12	raft	raft	ADJ
dti-2185	22	13	overall	overall	ADJ
dti-2185	22	14	membrane	membrane	NOUN
dti-2185	22	15	lipid	lipid	NOUN
dti-2185	22	16	bilayers	bilayer	NOUN
dti-2185	22	17	and	and	CCONJ
dti-2185	22	18	whether	whether	SCONJ
dti-2185	22	19	such	such	ADJ
dti-2185	22	20	interaction	interaction	NOUN
dti-2185	22	21	at	at	ADP
dti-2185	22	22	a	a	DET
dti-2185	22	23	membrane	membrane	NOUN
dti-2185	22	24	lipid	lipid	NOUN
dti-2185	22	25	level	level	NOUN
dti-2185	22	26	is	be	AUX
dti-2185	22	27	linked	link	VERB
dti-2185	22	28	to	to	ADP
dti-2185	22	29	pharmacological	pharmacological	ADJ
dti-2185	22	30	and	and	CCONJ
dti-2185	22	31	cytotoxic	cytotoxic	ADJ
dti-2185	22	32	effects	effect	NOUN
dti-2185	22	33	of	of	ADP
dti-2185	22	34	drugs	drug	NOUN
dti-2185	22	35	.	.	PUNCT
dti-2185	23	1	while	while	SCONJ
dti-2185	23	2	cholesterol	cholesterol	NOUN
dti-2185	23	3	is	be	AUX
dti-2185	23	4	essential	essential	ADJ
dti-2185	23	5	to	to	PART
dti-2185	23	6	raft	raft	VERB
dti-2185	23	7	and	and	CCONJ
dti-2185	23	8	caveola	caveola	VERB
dti-2185	23	9	formation	formation	NOUN
dti-2185	23	10	,	,	PUNCT
dti-2185	23	11	the	the	DET
dti-2185	23	12	regulatory	regulatory	ADJ
dti-2185	23	13	effects	effect	NOUN
dti-2185	23	14	of	of	ADP
dti-2185	23	15	membrane	membrane	NOUN
dti-2185	23	16	domains	domain	NOUN
dti-2185	23	17	on	on	ADP
dti-2185	23	18	receptors	receptor	NOUN
dti-2185	23	19	and	and	CCONJ
dti-2185	23	20	ion	ion	NOUN
dti-2185	23	21	channels	channel	NOUN
dti-2185	23	22	were	be	AUX
dti-2185	23	23	confirmed	confirm	VERB
dti-2185	23	24	by	by	ADP
dti-2185	23	25	depleting	deplete	VERB
dti-2185	23	26	cholesterol	cholesterol	NOUN
dti-2185	23	27	in	in	ADP
dti-2185	23	28	plasma	plasma	NOUN
dti-2185	23	29	membranes	membrane	NOUN
dti-2185	23	30	(	(	PUNCT
dti-2185	23	31	12	12	NUM
dti-2185	23	32	-	-	SYM
dti-2185	23	33	15	15	NUM
dti-2185	23	34	)	)	PUNCT
dti-2185	23	35	.	.	PUNCT
dti-2185	24	1	the	the	DET
dti-2185	24	2	purpose	purpose	NOUN
dti-2185	24	3	of	of	ADP
dti-2185	24	4	the	the	DET
dti-2185	24	5	present	present	ADJ
dti-2185	24	6	study	study	NOUN
dti-2185	24	7	is	be	AUX
dti-2185	24	8	to	to	PART
dti-2185	24	9	review	review	VERB
dti-2185	24	10	the	the	DET
dti-2185	24	11	interaction	interaction	NOUN
dti-2185	24	12	of	of	ADP
dti-2185	24	13	drugs	drug	NOUN
dti-2185	24	14	with	with	ADP
dti-2185	24	15	membrane	membrane	NOUN
dti-2185	24	16	lipid	lipid	NOUN
dti-2185	24	17	rafts	raft	NOUN
dti-2185	24	18	and	and	CCONJ
dti-2185	24	19	the	the	DET
dti-2185	24	20	membranes	membrane	NOUN
dti-2185	24	21	surrounding	surround	VERB
dti-2185	24	22	such	such	ADJ
dti-2185	24	23	domains	domain	NOUN
dti-2185	24	24	by	by	ADP
dti-2185	24	25	searching	search	VERB
dti-2185	24	26	scientific	scientific	ADJ
dti-2185	24	27	articles	article	NOUN
dti-2185	24	28	from	from	ADP
dti-2185	24	29	a	a	DET
dti-2185	24	30	mechanistic	mechanistic	ADJ
dti-2185	24	31	point	point	NOUN
dti-2185	24	32	of	of	ADP
dti-2185	24	33	view	view	NOUN
dti-2185	24	34	in	in	ADP
dti-2185	24	35	order	order	NOUN
dti-2185	24	36	to	to	PART
dti-2185	24	37	gain	gain	VERB
dti-2185	24	38	new	new	ADJ
dti-2185	24	39	insights	insight	NOUN
dti-2185	24	40	into	into	ADP
dti-2185	24	41	a	a	DET
dti-2185	24	42	drug	drug	NOUN
dti-2185	24	43	target	target	NOUN
dti-2185	24	44	.	.	PUNCT
dti-2185	25	1	since	since	SCONJ
dti-2185	25	2	various	various	ADJ
dti-2185	25	3	proteins	protein	NOUN
dti-2185	25	4	embedded	embed	VERB
dti-2185	25	5	in	in	ADP
dti-2185	25	6	membranes	membrane	NOUN
dti-2185	25	7	are	be	AUX
dti-2185	25	8	functionally	functionally	ADV
dti-2185	25	9	modulated	modulate	VERB
dti-2185	25	10	by	by	ADP
dti-2185	25	11	membrane	membrane	NOUN
dti-2185	25	12	fluidity	fluidity	NOUN
dti-2185	25	13	,	,	PUNCT
dti-2185	25	14	order	order	NOUN
dti-2185	25	15	and	and	CCONJ
dti-2185	25	16	phase	phase	NOUN
dti-2185	25	17	transition	transition	NOUN
dti-2185	25	18	,	,	PUNCT
dti-2185	25	19	the	the	DET
dti-2185	25	20	focus	focus	NOUN
dti-2185	25	21	of	of	ADP
dti-2185	25	22	our	our	PRON
dti-2185	25	23	review	review	NOUN
dti-2185	25	24	is	be	AUX
dti-2185	25	25	on	on	ADP
dti-2185	25	26	addressing	address	VERB
dti-2185	25	27	the	the	DET
dti-2185	25	28	question	question	NOUN
dti-2185	25	29	whether	whether	SCONJ
dti-2185	25	30	drugs	drug	NOUN
dti-2185	25	31	modify	modify	VERB
dti-2185	25	32	the	the	DET
dti-2185	25	33	physicochemical	physicochemical	ADJ
dti-2185	25	34	properties	property	NOUN
dti-2185	25	35	of	of	ADP
dti-2185	25	36	raft	raft	NOUN
dti-2185	25	37	-	-	PUNCT
dti-2185	25	38	constituting	constitute	VERB
dti-2185	25	39	and	and	CCONJ
dti-2185	25	40	raft	raft	NOUN
dti-2185	25	41	-	-	PUNCT
dti-2185	25	42	surrounding	surround	VERB
dti-2185	25	43	membranes	membrane	NOUN
dti-2185	25	44	to	to	PART
dti-2185	25	45	affect	affect	VERB
dti-2185	25	46	the	the	DET
dti-2185	25	47	formation	formation	NOUN
dti-2185	25	48	,	,	PUNCT
dti-2185	25	49	stability	stability	NOUN
dti-2185	25	50	and	and	CCONJ
dti-2185	25	51	integrity	integrity	NOUN
dti-2185	25	52	of	of	ADP
dti-2185	25	53	lipid	lipid	NOUN
dti-2185	25	54	raft	raft	NOUN
dti-2185	25	55	membrane	membrane	NOUN
dti-2185	25	56	domains	domain	NOUN
dti-2185	25	57	.	.	PUNCT
dti-2185	26	1	methods	method	NOUN
dti-2185	26	2	the	the	DET
dti-2185	26	3	present	present	ADJ
dti-2185	26	4	review	review	NOUN
dti-2185	26	5	is	be	AUX
dti-2185	26	6	based	base	VERB
dti-2185	26	7	on	on	ADP
dti-2185	26	8	articles	article	NOUN
dti-2185	26	9	that	that	PRON
dti-2185	26	10	were	be	AUX
dti-2185	26	11	retrieved	retrieve	VERB
dti-2185	26	12	from	from	ADP
dti-2185	26	13	pubmed	pubmed	PROPN
dti-2185	26	14	/	/	SYM
dti-2185	26	15	medline	medline	NOUN
dti-2185	26	16	and	and	CCONJ
dti-2185	26	17	google	google	PROPN
dti-2185	26	18	scholar	scholar	NOUN
dti-2185	26	19	by	by	ADP
dti-2185	26	20	searching	search	VERB
dti-2185	26	21	databases	database	NOUN
dti-2185	26	22	from	from	ADP
dti-2185	26	23	2000	2000	NUM
dti-2185	26	24	to	to	ADP
dti-2185	26	25	2020	2020	NUM
dti-2185	26	26	.	.	PUNCT
dti-2185	27	1	the	the	DET
dti-2185	27	2	publications	publication	NOUN
dti-2185	27	3	earlier	early	ADV
dti-2185	27	4	than	than	ADP
dti-2185	27	5	2000	2000	NUM
dti-2185	27	6	were	be	AUX
dti-2185	27	7	exceptionally	exceptionally	ADV
dti-2185	27	8	cited	cite	VERB
dti-2185	27	9	if	if	SCONJ
dti-2185	27	10	they	they	PRON
dti-2185	27	11	are	be	AUX
dti-2185	27	12	essential	essential	ADJ
dti-2185	27	13	to	to	ADP
dti-2185	27	14	advancing	advance	VERB
dti-2185	27	15	the	the	DET
dti-2185	27	16	discussion	discussion	NOUN
dti-2185	27	17	.	.	PUNCT
dti-2185	28	1	research	research	NOUN
dti-2185	28	2	papers	paper	NOUN
dti-2185	28	3	published	publish	VERB
dti-2185	28	4	in	in	ADP
dti-2185	28	5	english	english	PROPN
dti-2185	28	6	in	in	ADP
dti-2185	28	7	internationally	internationally	ADV
dti-2185	28	8	recognized	recognize	VERB
dti-2185	28	9	journals	journal	NOUN
dti-2185	28	10	and	and	CCONJ
dti-2185	28	11	online	online	ADJ
dti-2185	28	12	journals	journal	NOUN
dti-2185	28	13	were	be	AUX
dti-2185	28	14	preferred	prefer	VERB
dti-2185	28	15	,	,	PUNCT
dti-2185	28	16	but	but	CCONJ
dti-2185	28	17	review	review	NOUN
dti-2185	28	18	articles	article	NOUN
dti-2185	28	19	were	be	AUX
dti-2185	28	20	additionally	additionally	ADV
dti-2185	28	21	used	use	VERB
dti-2185	28	22	to	to	PART
dti-2185	28	23	deepen	deepen	VERB
dti-2185	28	24	understanding	understanding	NOUN
dti-2185	28	25	of	of	ADP
dti-2185	28	26	the	the	DET
dti-2185	28	27	concept	concept	NOUN
dti-2185	28	28	of	of	ADP
dti-2185	28	29	plasma	plasma	NOUN
dti-2185	28	30	membranes	membrane	NOUN
dti-2185	28	31	and	and	CCONJ
dti-2185	28	32	the	the	DET
dti-2185	28	33	mode	mode	NOUN
dti-2185	28	34	of	of	ADP
dti-2185	28	35	drug	drug	NOUN
dti-2185	28	36	action	action	NOUN
dti-2185	28	37	.	.	PUNCT
dti-2185	29	1	for	for	ADP
dti-2185	29	2	reviewing	review	VERB
dti-2185	29	3	as	as	ADP
dti-2185	29	4	diverse	diverse	ADJ
dti-2185	29	5	drugs	drug	NOUN
dti-2185	29	6	as	as	ADP
dti-2185	29	7	possible	possible	ADJ
dti-2185	29	8	without	without	ADP
dti-2185	29	9	confining	confine	VERB
dti-2185	29	10	to	to	ADP
dti-2185	29	11	a	a	DET
dti-2185	29	12	specific	specific	ADJ
dti-2185	29	13	class	class	NOUN
dti-2185	29	14	of	of	ADP
dti-2185	29	15	drug	drug	NOUN
dti-2185	29	16	,	,	PUNCT
dti-2185	29	17	the	the	DET
dti-2185	29	18	literature	literature	NOUN
dti-2185	29	19	searches	search	NOUN
dti-2185	29	20	were	be	AUX
dti-2185	29	21	carried	carry	VERB
dti-2185	29	22	out	out	ADP
dti-2185	29	23	using	use	VERB
dti-2185	29	24	the	the	DET
dti-2185	29	25	following	follow	VERB
dti-2185	29	26	terms	term	NOUN
dti-2185	29	27	or	or	CCONJ
dti-2185	29	28	combinations	combination	NOUN
dti-2185	29	29	thereof	thereof	ADV
dti-2185	29	30	:	:	PUNCT
dti-2185	29	31	“	"	PUNCT
dti-2185	29	32	lipid	lipid	ADJ
dti-2185	29	33	raft	raft	NOUN
dti-2185	29	34	,	,	PUNCT
dti-2185	29	35	”	"	PUNCT
dti-2185	29	36	“	"	PUNCT
dti-2185	29	37	caveola	caveola	NOUN
dti-2185	29	38	,	,	PUNCT
dti-2185	29	39	”	"	PUNCT
dti-2185	29	40	“	"	PUNCT
dti-2185	29	41	membrane	membrane	NOUN
dti-2185	29	42	domain	domain	NOUN
dti-2185	29	43	,	,	PUNCT
dti-2185	29	44	”	"	PUNCT
dti-2185	29	45	“	"	PUNCT
dti-2185	29	46	membrane	membrane	NOUN
dti-2185	29	47	interaction	interaction	NOUN
dti-2185	29	48	,	,	PUNCT
dti-2185	29	49	”	"	PUNCT
dti-2185	29	50	“	"	PUNCT
dti-2185	29	51	fluidity	fluidity	NOUN
dti-2185	29	52	,	,	PUNCT
dti-2185	29	53	”	"	PUNCT
dti-2185	29	54	“	"	PUNCT
dti-2185	29	55	receptor	receptor	NOUN
dti-2185	29	56	,	,	PUNCT
dti-2185	29	57	”	"	PUNCT
dti-2185	29	58	“	"	PUNCT
dti-2185	29	59	channel	channel	NOUN
dti-2185	29	60	”	"	PUNCT
dti-2185	29	61	and	and	CCONJ
dti-2185	29	62	“	"	PUNCT
dti-2185	29	63	enzyme	enzyme	NOUN
dti-2185	29	64	.	.	PUNCT
dti-2185	29	65	”	"	PUNCT
dti-2185	30	1	collected	collect	VERB
dti-2185	30	2	articles	article	NOUN
dti-2185	30	3	were	be	AUX
dti-2185	30	4	independently	independently	ADV
dti-2185	30	5	reviewed	review	VERB
dti-2185	30	6	by	by	ADP
dti-2185	30	7	title	title	NOUN
dti-2185	30	8	,	,	PUNCT
dti-2185	30	9	abstract	abstract	ADJ
dti-2185	30	10	and	and	CCONJ
dti-2185	30	11	text	text	NOUN
dti-2185	30	12	for	for	ADP
dti-2185	30	13	relevance	relevance	NOUN
dti-2185	30	14	with	with	ADP
dti-2185	30	15	preference	preference	NOUN
dti-2185	30	16	to	to	ADP
dti-2185	30	17	more	more	ADV
dti-2185	30	18	recent	recent	ADJ
dti-2185	30	19	publications	publication	NOUN
dti-2185	30	20	.	.	PUNCT
dti-2185	31	1	results	result	NOUN
dti-2185	31	2	and	and	CCONJ
dti-2185	31	3	discussion	discussion	NOUN
dti-2185	31	4	drug	drug	NOUN
dti-2185	31	5	and	and	CCONJ
dti-2185	31	6	raft	raft	NOUN
dti-2185	31	7	interaction	interaction	NOUN
dti-2185	31	8	methodology	methodology	NOUN
dti-2185	31	9	since	since	SCONJ
dti-2185	31	10	the	the	DET
dti-2185	31	11	methodology	methodology	NOUN
dti-2185	31	12	of	of	ADP
dti-2185	31	13	drug	drug	NOUN
dti-2185	31	14	and	and	CCONJ
dti-2185	31	15	membrane	membrane	NOUN
dti-2185	31	16	raft	raft	NOUN
dti-2185	31	17	interaction	interaction	NOUN
dti-2185	31	18	is	be	AUX
dti-2185	31	19	essential	essential	ADJ
dti-2185	31	20	to	to	PART
dti-2185	31	21	facilitate	facilitate	VERB
dti-2185	31	22	readers	reader	NOUN
dti-2185	31	23	’	’	PART
dti-2185	31	24	understanding	understanding	NOUN
dti-2185	31	25	of	of	ADP
dti-2185	31	26	individual	individual	ADJ
dti-2185	31	27	studies	study	NOUN
dti-2185	31	28	,	,	PUNCT
dti-2185	31	29	representative	representative	ADJ
dti-2185	31	30	experiments	experiment	NOUN
dti-2185	31	31	are	be	AUX
dti-2185	31	32	mentioned	mention	VERB
dti-2185	31	33	as	as	SCONJ
dti-2185	31	34	follows	follow	VERB
dti-2185	31	35	.	.	PUNCT
dti-2185	32	1	in	in	ADP
dti-2185	32	2	in	in	ADP
dti-2185	32	3	vitro	vitro	X
dti-2185	32	4	experiments	experiment	NOUN
dti-2185	32	5	,	,	PUNCT
dti-2185	32	6	drugs	drug	NOUN
dti-2185	32	7	are	be	AUX
dti-2185	32	8	subjected	subject	VERB
dti-2185	32	9	to	to	ADP
dti-2185	32	10	the	the	DET
dti-2185	32	11	reaction	reaction	NOUN
dti-2185	32	12	with	with	ADP
dti-2185	32	13	raft	raft	NOUN
dti-2185	32	14	model	model	NOUN
dti-2185	32	15	(	(	PUNCT
dti-2185	32	16	raft	raft	NOUN
dti-2185	32	17	-	-	PUNCT
dti-2185	32	18	like	like	ADJ
dti-2185	32	19	)	)	PUNCT
dti-2185	32	20	membranes	membrane	NOUN
dti-2185	32	21	or	or	CCONJ
dti-2185	32	22	liposomes	liposome	NOUN
dti-2185	32	23	that	that	PRON
dti-2185	32	24	mimic	mimic	VERB
dti-2185	32	25	the	the	DET
dti-2185	32	26	lipid	lipid	NOUN
dti-2185	32	27	composition	composition	NOUN
dti-2185	32	28	and	and	CCONJ
dti-2185	32	29	property	property	NOUN
dti-2185	32	30	of	of	ADP
dti-2185	32	31	lipid	lipid	NOUN
dti-2185	32	32	raft	raft	NOUN
dti-2185	32	33	micro	micro	NOUN
dti-2185	32	34	domains	domain	NOUN
dti-2185	32	35	(	(	PUNCT
dti-2185	32	36	16,17	16,17	NUM
dti-2185	32	37	)	)	PUNCT
dti-2185	32	38	.	.	PUNCT
dti-2185	33	1	ternary	ternary	ADJ
dti-2185	33	2	lipid	lipid	NOUN
dti-2185	33	3	membranes	membrane	NOUN
dti-2185	33	4	are	be	AUX
dti-2185	33	5	used	use	VERB
dti-2185	33	6	as	as	ADP
dti-2185	33	7	a	a	DET
dti-2185	33	8	raft	raft	NOUN
dti-2185	33	9	model	model	NOUN
dti-2185	33	10	,	,	PUNCT
dti-2185	33	11	which	which	PRON
dti-2185	33	12	is	be	AUX
dti-2185	33	13	frequently	frequently	ADV
dti-2185	33	14	prepared	prepare	VERB
dti-2185	33	15	with	with	ADP
dti-2185	33	16	an	an	DET
dti-2185	33	17	equimolar	equimolar	NOUN
dti-2185	33	18	mixture	mixture	NOUN
dti-2185	33	19	of	of	ADP
dti-2185	33	20	1	1	NUM
dti-2185	33	21	-	-	PUNCT
dti-2185	33	22	palmitoyl-2	palmitoyl-2	VERB
dti-2185	33	23	-	-	PUNCT
dti-2185	33	24	oleoylphosphatidylcholine	oleoylphosphatidylcholine	NOUN
dti-2185	33	25	(	(	PUNCT
dti-2185	33	26	popc	popc	NOUN
dti-2185	33	27	)	)	PUNCT
dti-2185	33	28	,	,	PUNCT
dti-2185	33	29	sphingomyelin	sphingomyelin	NOUN
dti-2185	33	30	(	(	PUNCT
dti-2185	33	31	sm	sm	NOUN
dti-2185	33	32	)	)	PUNCT
dti-2185	33	33	and	and	CCONJ
dti-2185	33	34	cholesterol	cholesterol	NOUN
dti-2185	33	35	(	(	PUNCT
dti-2185	33	36	18	18	NUM
dti-2185	33	37	)	)	PUNCT
dti-2185	33	38	,	,	PUNCT
dti-2185	33	39	in	in	ADP
dti-2185	33	40	which	which	PRON
dti-2185	33	41	cholesterol	cholesterol	NOUN
dti-2185	33	42	functions	function	NOUN
dti-2185	33	43	as	as	ADP
dti-2185	33	44	a	a	DET
dti-2185	33	45	spacer	spacer	NOUN
dti-2185	33	46	between	between	ADP
dti-2185	33	47	sphingolipid	sphingolipid	PROPN
dti-2185	33	48	hydrocarbon	hydrocarbon	NOUN
dti-2185	33	49	chains	chain	NOUN
dti-2185	33	50	and	and	CCONJ
dti-2185	33	51	as	as	SCONJ
dti-2185	33	52	a	a	DET
dti-2185	33	53	glue	glue	NOUN
dti-2185	33	54	to	to	PART
dti-2185	33	55	keep	keep	VERB
dti-2185	33	56	the	the	DET
dti-2185	33	57	raft	raft	NOUN
dti-2185	33	58	assembly	assembly	NOUN
dti-2185	33	59	together	together	ADV
dti-2185	33	60	(	(	PUNCT
dti-2185	33	61	19	19	NUM
dti-2185	33	62	)	)	PUNCT
dti-2185	33	63	.	.	PUNCT
dti-2185	34	1	such	such	ADJ
dti-2185	34	2	raft	raft	NOUN
dti-2185	34	3	model	model	NOUN
dti-2185	34	4	membranes	membrane	NOUN
dti-2185	34	5	have	have	VERB
dti-2185	34	6	the	the	DET
dti-2185	34	7	advantage	advantage	NOUN
dti-2185	34	8	that	that	SCONJ
dti-2185	34	9	the	the	DET
dti-2185	34	10	membrane	membrane	NOUN
dti-2185	34	11	effects	effect	NOUN
dti-2185	34	12	of	of	ADP
dti-2185	34	13	drugs	drug	NOUN
dti-2185	34	14	can	can	AUX
dti-2185	34	15	be	be	AUX
dti-2185	34	16	determined	determine	VERB
dti-2185	34	17	more	more	ADV
dti-2185	34	18	easily	easily	ADV
dti-2185	34	19	than	than	ADP
dti-2185	34	20	in	in	ADP
dti-2185	34	21	vivo	vivo	ADJ
dti-2185	34	22	experiments	experiment	NOUN
dti-2185	34	23	(	(	PUNCT
dti-2185	34	24	20	20	NUM
dti-2185	34	25	)	)	PUNCT
dti-2185	34	26	.	.	PUNCT
dti-2185	35	1	lipid	lipid	NOUN
dti-2185	35	2	rafts	raft	NOUN
dti-2185	35	3	isolated	isolate	VERB
dti-2185	35	4	from	from	ADP
dti-2185	35	5	cells	cell	NOUN
dti-2185	35	6	are	be	AUX
dti-2185	35	7	also	also	ADV
dti-2185	35	8	used	use	VERB
dti-2185	35	9	experimentally	experimentally	ADV
dti-2185	35	10	.	.	PUNCT
dti-2185	36	1	since	since	SCONJ
dti-2185	36	2	lipid	lipid	NOUN
dti-2185	36	3	rafts	raft	NOUN
dti-2185	36	4	are	be	AUX
dti-2185	36	5	relatively	relatively	ADV
dti-2185	36	6	insoluble	insoluble	ADJ
dti-2185	36	7	in	in	ADP
dti-2185	36	8	cold	cold	ADJ
dti-2185	36	9	non	non	ADJ
dti-2185	36	10	-	-	ADJ
dti-2185	36	11	ionic	ionic	ADJ
dti-2185	36	12	detergents	detergent	NOUN
dti-2185	36	13	,	,	PUNCT
dti-2185	36	14	cells	cell	NOUN
dti-2185	36	15	are	be	AUX
dti-2185	36	16	treated	treat	VERB
dti-2185	36	17	with	with	ADP
dti-2185	36	18	triton	triton	PROPN
dti-2185	36	19	x-100	x-100	PROPN
dti-2185	36	20	and	and	CCONJ
dti-2185	36	21	membrane	membrane	NOUN
dti-2185	36	22	lipid	lipid	NOUN
dti-2185	36	23	rafts	raft	NOUN
dti-2185	36	24	are	be	AUX
dti-2185	36	25	fractionated	fractionate	VERB
dti-2185	36	26	by	by	ADP
dti-2185	36	27	sucrose	sucrose	PROPN
dti-2185	36	28	density	density	NOUN
dti-2185	36	29	gradient	gradient	NOUN
dti-2185	36	30	centrifugation	centrifugation	NOUN
dti-2185	36	31	(	(	PUNCT
dti-2185	36	32	sdgc	sdgc	NOUN
dti-2185	36	33	)	)	PUNCT
dti-2185	36	34	(	(	PUNCT
dti-2185	36	35	21	21	NUM
dti-2185	36	36	)	)	PUNCT
dti-2185	36	37	.	.	PUNCT
dti-2185	37	1	in	in	ADP
dti-2185	37	2	in	in	ADP
dti-2185	37	3	vivo	vivo	ADJ
dti-2185	37	4	experiments	experiment	NOUN
dti-2185	37	5	,	,	PUNCT
dti-2185	37	6	human	human	ADJ
dti-2185	37	7	and	and	CCONJ
dti-2185	37	8	animal	animal	NOUN
dti-2185	37	9	subjects	subject	NOUN
dti-2185	37	10	are	be	AUX
dti-2185	37	11	treated	treat	VERB
dti-2185	37	12	with	with	ADP
dti-2185	37	13	drugs	drug	NOUN
dti-2185	37	14	,	,	PUNCT
dti-2185	37	15	followed	follow	VERB
dti-2185	37	16	by	by	ADP
dti-2185	37	17	sdgc	sdgc	NOUN
dti-2185	37	18	to	to	PART
dti-2185	37	19	isolate	isolate	VERB
dti-2185	37	20	cellular	cellular	ADJ
dti-2185	37	21	membrane	membrane	NOUN
dti-2185	37	22	lipid	lipid	NOUN
dti-2185	37	23	rafts	raft	NOUN
dti-2185	37	24	.	.	PUNCT
dti-2185	38	1	cholesterol	cholesterol	NOUN
dti-2185	38	2	is	be	AUX
dti-2185	38	3	not	not	PART
dti-2185	38	4	only	only	ADV
dti-2185	38	5	a	a	DET
dti-2185	38	6	critical	critical	ADJ
dti-2185	38	7	determinant	determinant	NOUN
dti-2185	38	8	for	for	ADP
dti-2185	38	9	membrane	membrane	NOUN
dti-2185	38	10	fluidity	fluidity	NOUN
dti-2185	38	11	but	but	CCONJ
dti-2185	38	12	also	also	ADV
dti-2185	38	13	an	an	DET
dti-2185	38	14	essential	essential	ADJ
dti-2185	38	15	component	component	NOUN
dti-2185	38	16	to	to	PART
dti-2185	38	17	form	form	VERB
dti-2185	38	18	the	the	DET
dti-2185	38	19	lo	lo	PROPN
dti-2185	38	20	membrane	membrane	NOUN
dti-2185	38	21	domains	domain	NOUN
dti-2185	38	22	.	.	PUNCT
dti-2185	39	1	cellular	cellular	ADJ
dti-2185	39	2	cholesterol	cholesterol	NOUN
dti-2185	39	3	contents	content	NOUN
dti-2185	39	4	are	be	AUX
dti-2185	39	5	manipulated	manipulate	VERB
dti-2185	39	6	by	by	ADP
dti-2185	39	7	treating	treat	VERB
dti-2185	39	8	animals	animal	NOUN
dti-2185	39	9	with	with	ADP
dti-2185	39	10	cholesterol	cholesterol	NOUN
dti-2185	39	11	metabolic	metabolic	NOUN
dti-2185	39	12	inhibitors	inhibitor	NOUN
dti-2185	39	13	,	,	PUNCT
dti-2185	39	14	culturing	culture	VERB
dti-2185	39	15	cells	cell	NOUN
dti-2185	39	16	in	in	ADP
dti-2185	39	17	cholesterol	cholesterol	NOUN
dti-2185	39	18	-	-	PUNCT
dti-2185	39	19	deficient	deficient	ADJ
dti-2185	39	20	media	medium	NOUN
dti-2185	39	21	and	and	CCONJ
dti-2185	39	22	using	use	VERB
dti-2185	39	23	cholesterol	cholesterol	NOUN
dti-2185	39	24	-	-	PUNCT
dti-2185	39	25	depleting	deplete	VERB
dti-2185	39	26	agents	agent	NOUN
dti-2185	39	27	.	.	PUNCT
dti-2185	40	1	methyl	methyl	NOUN
dti-2185	40	2	-	-	PUNCT
dti-2185	40	3	βcyclodextrin	βcyclodextrin	NOUN
dti-2185	40	4	(	(	PUNCT
dti-2185	40	5	mbc	mbc	PROPN
dti-2185	40	6	)	)	PUNCT
dti-2185	40	7	,	,	PUNCT
dti-2185	40	8	to	to	PART
dti-2185	40	9	form	form	VERB
dti-2185	40	10	a	a	DET
dti-2185	40	11	2:1	2:1	NUM
dti-2185	40	12	complex	complex	NOUN
dti-2185	40	13	with	with	ADP
dti-2185	40	14	cholesterol	cholesterol	NOUN
dti-2185	40	15	(	(	PUNCT
dti-2185	40	16	22	22	NUM
dti-2185	40	17	)	)	PUNCT
dti-2185	40	18	,	,	PUNCT
dti-2185	40	19	is	be	AUX
dti-2185	40	20	most	most	ADV
dti-2185	40	21	widely	widely	ADV
dti-2185	40	22	used	use	VERB
dti-2185	40	23	for	for	ADP
dti-2185	40	24	cholesterol	cholesterol	NOUN
dti-2185	40	25	depletion	depletion	NOUN
dti-2185	40	26	(	(	PUNCT
dti-2185	40	27	23	23	NUM
dti-2185	40	28	)	)	PUNCT
dti-2185	40	29	.	.	PUNCT
dti-2185	41	1	drug	drug	NOUN
dti-2185	41	2	-	-	PUNCT
dti-2185	41	3	induced	induce	VERB
dti-2185	41	4	physicochemical	physicochemical	ADJ
dti-2185	41	5	or	or	CCONJ
dti-2185	41	6	biophysical	biophysical	ADJ
dti-2185	41	7	changes	change	NOUN
dti-2185	41	8	in	in	ADP
dti-2185	41	9	raft	raft	NOUN
dti-2185	41	10	model	model	NOUN
dti-2185	41	11	membranes	membrane	NOUN
dti-2185	41	12	and	and	CCONJ
dti-2185	41	13	membrane	membrane	NOUN
dti-2185	41	14	lipid	lipid	NOUN
dti-2185	41	15	rafts	raft	NOUN
dti-2185	41	16	are	be	AUX
dti-2185	41	17	determined	determine	VERB
dti-2185	41	18	by	by	ADP
dti-2185	41	19	fluorescence	fluorescence	NOUN
dti-2185	41	20	polarization	polarization	NOUN
dti-2185	41	21	(	(	PUNCT
dti-2185	41	22	fp	fp	X
dti-2185	41	23	)	)	PUNCT
dti-2185	41	24	or	or	CCONJ
dti-2185	41	25	anisotropy	anisotropy	VERB
dti-2185	41	26	(	(	PUNCT
dti-2185	41	27	fa	fa	NOUN
dti-2185	41	28	)	)	PUNCT
dti-2185	41	29	,	,	PUNCT
dti-2185	41	30	differential	differential	NOUN
dti-2185	41	31	scanning	scanning	NOUN
dti-2185	41	32	calorimetry	calorimetry	NOUN
dti-2185	41	33	(	(	PUNCT
dti-2185	41	34	dsc	dsc	NOUN
dti-2185	41	35	)	)	PUNCT
dti-2185	41	36	,	,	PUNCT
dti-2185	41	37	nuclear	nuclear	ADJ
dti-2185	41	38	magnetic	magnetic	ADJ
dti-2185	41	39	resonance	resonance	NOUN
dti-2185	41	40	(	(	PUNCT
dti-2185	41	41	nmr	nmr	NOUN
dti-2185	41	42	)	)	PUNCT
dti-2185	41	43	spectroscopy	spectroscopy	NOUN
dti-2185	41	44	,	,	PUNCT
dti-2185	41	45	neutron	neutron	NOUN
dti-2185	41	46	diffraction	diffraction	NOUN
dti-2185	41	47	(	(	PUNCT
dti-2185	41	48	nd	nd	NOUN
dti-2185	41	49	)	)	PUNCT
dti-2185	41	50	,	,	PUNCT
dti-2185	41	51	xray	xray	PROPN
dti-2185	41	52	diffraction	diffraction	NOUN
dti-2185	41	53	(	(	PUNCT
dti-2185	41	54	xd	xd	INTJ
dti-2185	41	55	)	)	PUNCT
dti-2185	41	56	and	and	CCONJ
dti-2185	41	57	their	their	PRON
dti-2185	41	58	complementary	complementary	ADJ
dti-2185	41	59	combination	combination	NOUN
dti-2185	41	60	.	.	PUNCT
dti-2185	42	1	general	general	ADJ
dti-2185	42	2	anesthetics	anesthetics	PROPN
dti-2185	42	3	general	general	ADJ
dti-2185	42	4	anesthetics	anesthetic	NOUN
dti-2185	42	5	and	and	CCONJ
dti-2185	42	6	their	their	PRON
dti-2185	42	7	related	related	ADJ
dti-2185	42	8	sedatives	sedative	NOUN
dti-2185	42	9	,	,	PUNCT
dti-2185	42	10	anxiolytics	anxiolytic	NOUN
dti-2185	42	11	and	and	CCONJ
dti-2185	42	12	adjuncts	adjunct	NOUN
dti-2185	42	13	act	act	NOUN
dti-2185	42	14	on	on	ADP
dti-2185	42	15	inhibitory	inhibitory	ADJ
dti-2185	42	16	γ	γ	PROPN
dti-2185	42	17	-	-	ADJ
dti-2185	42	18	aminobutyric	aminobutyric	ADJ
dti-2185	42	19	acid	acid	NOUN
dti-2185	42	20	type	type	NOUN
dti-2185	42	21	a	a	DET
dti-2185	42	22	(	(	PUNCT
dti-2185	42	23	gabaa	gabaa	NOUN
dti-2185	42	24	)	)	PUNCT
dti-2185	42	25	receptors	receptor	NOUN
dti-2185	42	26	and	and	CCONJ
dti-2185	42	27	excitatory	excitatory	NOUN
dti-2185	42	28	n	n	NOUN
dti-2185	42	29	-	-	PUNCT
dti-2185	42	30	methyl	methyl	NOUN
dti-2185	42	31	-	-	PUNCT
dti-2185	42	32	daspartate	daspartate	NOUN
dti-2185	42	33	(	(	PUNCT
dti-2185	42	34	nmda	nmda	ADJ
dti-2185	42	35	)	)	PUNCT
dti-2185	42	36	receptors	receptor	NOUN
dti-2185	42	37	(	(	PUNCT
dti-2185	42	38	24	24	NUM
dti-2185	42	39	)	)	PUNCT
dti-2185	42	40	.	.	PUNCT
dti-2185	43	1	intravenous	intravenous	ADJ
dti-2185	43	2	and	and	CCONJ
dti-2185	43	3	inhalational	inhalational	ADJ
dti-2185	43	4	anesthetics	anesthetic	NOUN
dti-2185	43	5	are	be	AUX
dti-2185	43	6	a	a	DET
dti-2185	43	7	positive	positive	ADJ
dti-2185	43	8	allosteric	allosteric	ADJ
dti-2185	43	9	modulator	modulator	NOUN
dti-2185	43	10	or	or	CCONJ
dti-2185	43	11	a	a	DET
dti-2185	43	12	direct	direct	ADJ
dti-2185	43	13	activator	activator	NOUN
dti-2185	43	14	of	of	ADP
dti-2185	43	15	gabaa	gabaa	NOUN
dti-2185	43	16	receptors	receptor	NOUN
dti-2185	43	17	to	to	PART
dti-2185	43	18	enhance	enhance	VERB
dti-2185	43	19	their	their	PRON
dti-2185	43	20	inhibitory	inhibitory	ADJ
dti-2185	43	21	functions	function	NOUN
dti-2185	43	22	,	,	PUNCT
dti-2185	43	23	inducing	induce	VERB
dti-2185	43	24	general	general	ADJ
dti-2185	43	25	anesthesia	anesthesia	NOUN
dti-2185	43	26	,	,	PUNCT
dti-2185	43	27	sedation	sedation	NOUN
dti-2185	43	28	,	,	PUNCT
dti-2185	43	29	anxiolysis	anxiolysis	NOUN
dti-2185	43	30	and	and	CCONJ
dti-2185	43	31	convulsion	convulsion	NOUN
dti-2185	43	32	cessation	cessation	NOUN
dti-2185	43	33	(	(	PUNCT
dti-2185	43	34	25	25	NUM
dti-2185	43	35	)	)	PUNCT
dti-2185	43	36	.	.	PUNCT
dti-2185	44	1	inhalational	inhalational	ADJ
dti-2185	44	2	anesthetics	anesthetic	NOUN
dti-2185	44	3	are	be	AUX
dti-2185	44	4	also	also	ADV
dti-2185	44	5	a	a	DET
dti-2185	44	6	non	non	ADJ
dti-2185	44	7	-	-	ADJ
dti-2185	44	8	competitive	competitive	ADJ
dti-2185	44	9	antagonist	antagonist	NOUN
dti-2185	44	10	of	of	ADP
dti-2185	44	11	nmda	nmda	ADJ
dti-2185	44	12	receptors	receptor	NOUN
dti-2185	44	13	to	to	PART
dti-2185	44	14	reduce	reduce	VERB
dti-2185	44	15	neuronal	neuronal	ADJ
dti-2185	44	16	excitation	excitation	NOUN
dti-2185	44	17	,	,	PUNCT
dti-2185	44	18	producing	produce	VERB
dti-2185	44	19	analgesic	analgesic	ADJ
dti-2185	44	20	,	,	PUNCT
dti-2185	44	21	sedative	sedative	ADJ
dti-2185	44	22	and	and	CCONJ
dti-2185	44	23	anesthesia	anesthesia	NOUN
dti-2185	44	24	-	-	PUNCT
dti-2185	44	25	maintaining	maintain	VERB
dti-2185	44	26	effects	effect	NOUN
dti-2185	44	27	(	(	PUNCT
dti-2185	44	28	26,27	26,27	NUM
dti-2185	44	29	)	)	PUNCT
dti-2185	44	30	.	.	PUNCT
dti-2185	45	1	these	these	DET
dti-2185	45	2	anesthesiarelevant	anesthesiarelevant	ADJ
dti-2185	45	3	gabaa	gabaa	NOUN
dti-2185	45	4	receptors	receptor	NOUN
dti-2185	45	5	and	and	CCONJ
dti-2185	45	6	nmda	nmda	ADJ
dti-2185	45	7	receptors	receptor	NOUN
dti-2185	45	8	are	be	AUX
dti-2185	45	9	associated	associate	VERB
dti-2185	45	10	with	with	ADP
dti-2185	45	11	lipid	lipid	NOUN
dti-2185	45	12	raft	raft	NOUN
dti-2185	45	13	membrane	membrane	NOUN
dti-2185	45	14	domains	domain	NOUN
dti-2185	45	15	(	(	PUNCT
dti-2185	45	16	28,29	28,29	NUM
dti-2185	45	17	)	)	PUNCT
dti-2185	45	18	.	.	PUNCT
dti-2185	46	1	results	result	NOUN
dti-2185	46	2	of	of	ADP
dti-2185	46	3	the	the	DET
dti-2185	46	4	literature	literature	NOUN
dti-2185	46	5	search	search	NOUN
dti-2185	46	6	indicated	indicate	VERB
dti-2185	46	7	that	that	SCONJ
dti-2185	46	8	general	general	ADJ
dti-2185	46	9	anesthetics	anesthetic	NOUN
dti-2185	46	10	interact	interact	VERB
dti-2185	46	11	with	with	ADP
dti-2185	46	12	membrane	membrane	NOUN
dti-2185	46	13	lipid	lipid	NOUN
dti-2185	46	14	rafts	raft	NOUN
dti-2185	46	15	and	and	CCONJ
dti-2185	46	16	membranes	membrane	NOUN
dti-2185	46	17	as	as	SCONJ
dti-2185	46	18	shown	show	VERB
dti-2185	46	19	in	in	ADP
dti-2185	46	20	table	table	NOUN
dti-2185	46	21	i.	i.	NOUN
dti-2185	46	22	intravenous	intravenous	ADJ
dti-2185	46	23	anesthetic	anesthetic	ADJ
dti-2185	46	24	propofol	propofol	NOUN
dti-2185	46	25	fp	fp	ADP
dti-2185	46	26	experiments	experiment	NOUN
dti-2185	46	27	demonstrated	demonstrate	VERB
dti-2185	46	28	that	that	SCONJ
dti-2185	46	29	propofol	propofol	NOUN
dti-2185	46	30	structurespecifically	structurespecifically	ADV
dti-2185	46	31	interacts	interact	VERB
dti-2185	46	32	with	with	ADP
dti-2185	46	33	binary	binary	ADJ
dti-2185	46	34	liposomal	liposomal	ADJ
dti-2185	46	35	membranes	membrane	NOUN
dti-2185	46	36	prepared	prepare	VERB
dti-2185	46	37	with	with	ADP
dti-2185	46	38	80	80	NUM
dti-2185	46	39	mol%	mol%	PROPN
dti-2185	46	40	popc	popc	NOUN
dti-2185	46	41	and	and	CCONJ
dti-2185	46	42	20	20	NUM
dti-2185	46	43	mol%	mol%	PROPN
dti-2185	46	44	cholesterol	cholesterol	NOUN
dti-2185	46	45	(	(	PUNCT
dti-2185	46	46	30	30	NUM
dti-2185	46	47	)	)	PUNCT
dti-2185	46	48	and	and	CCONJ
dti-2185	46	49	quinary	quinary	ADJ
dti-2185	46	50	liposomal	liposomal	ADJ
dti-2185	46	51	membranes	membrane	NOUN
dti-2185	46	52	prepared	prepare	VERB
dti-2185	46	53	with	with	ADP
dti-2185	46	54	55	55	NUM
dti-2185	46	55	mol%	mol%	PROPN
dti-2185	46	56	phospholipids	phospholipid	NOUN
dti-2185	46	57	(	(	PUNCT
dti-2185	46	58	popc	popc	NOUN
dti-2185	46	59	,	,	PUNCT
dti-2185	46	60	sm	sm	INTJ
dti-2185	46	61	,	,	PUNCT
dti-2185	46	62	1	1	NUM
dti-2185	46	63	-	-	PUNCT
dti-2185	46	64	palmitoyl-2	palmitoyl-2	VERB
dti-2185	46	65	-	-	PUNCT
dti-2185	46	66	oleoylphosphatidylethanolamine	oleoylphosphatidylethanolamine	ADJ
dti-2185	46	67	(	(	PUNCT
dti-2185	46	68	pope	pope	NOUN
dti-2185	46	69	)	)	PUNCT
dti-2185	46	70	and	and	CCONJ
dti-2185	46	71	1	1	NUM
dti-2185	46	72	-	-	PUNCT
dti-2185	46	73	palmitoyl-2	palmitoyl-2	VERB
dti-2185	46	74	-	-	PUNCT
dti-2185	46	75	oleoylphosphatidylserine	oleoylphosphatidylserine	ADJ
dti-2185	46	76	(	(	PUNCT
dti-2185	46	77	pops	pop	NOUN
dti-2185	46	78	)	)	PUNCT
dti-2185	46	79	)	)	PUNCT
dti-2185	46	80	and	and	CCONJ
dti-2185	46	81	45	45	NUM
dti-2185	46	82	mol%	mol%	PROPN
dti-2185	46	83	cholesterol	cholesterol	NOUN
dti-2185	46	84	(	(	PUNCT
dti-2185	46	85	31	31	NUM
dti-2185	46	86	)	)	PUNCT
dti-2185	46	87	,	,	PUNCT
dti-2185	46	88	resulting	result	VERB
dti-2185	46	89	in	in	ADP
dti-2185	46	90	an	an	DET
dti-2185	46	91	increase	increase	NOUN
dti-2185	46	92	of	of	ADP
dti-2185	46	93	membrane	membrane	NOUN
dti-2185	46	94	fluidity	fluidity	NOUN
dti-2185	46	95	at	at	ADP
dti-2185	46	96	clinically	clinically	ADV
dti-2185	46	97	relevant	relevant	ADJ
dti-2185	46	98	0.125	0.125	NUM
dti-2185	46	99	-	-	SYM
dti-2185	46	100	10	10	NUM
dti-2185	46	101	μm	μm	NOUN
dti-2185	46	102	.	.	PUNCT
dti-2185	47	1	lo	lo	NOUN
dti-2185	47	2	and	and	CCONJ
dti-2185	47	3	ld	ld	PROPN
dti-2185	47	4	phase	phase	NOUN
dti-2185	47	5	equilibrium	equilibrium	NOUN
dti-2185	47	6	is	be	AUX
dti-2185	47	7	present	present	ADJ
dti-2185	47	8	in	in	ADP
dti-2185	47	9	giant	giant	ADJ
dti-2185	47	10	plasma	plasma	NOUN
dti-2185	47	11	membrane	membrane	NOUN
dti-2185	47	12	vesicles	vesicle	NOUN
dti-2185	47	13	(	(	PUNCT
dti-2185	47	14	gpmvs	gpmvs	ADJ
dti-2185	47	15	)	)	PUNCT
dti-2185	47	16	isolated	isolate	VERB
dti-2185	47	17	from	from	ADP
dti-2185	47	18	rat	rat	NOUN
dti-2185	47	19	basophil	basophil	NOUN
dti-2185	47	20	leukemia	leukemia	NOUN
dti-2185	47	21	cells	cell	NOUN
dti-2185	47	22	,	,	PUNCT
dti-2185	47	23	which	which	PRON
dti-2185	47	24	are	be	AUX
dti-2185	47	25	used	use	VERB
dti-2185	47	26	as	as	ADP
dti-2185	47	27	a	a	DET
dti-2185	47	28	model	model	NOUN
dti-2185	47	29	of	of	ADP
dti-2185	47	30	membrane	membrane	NOUN
dti-2185	47	31	heterogeneity	heterogeneity	NOUN
dti-2185	47	32	for	for	ADP
dti-2185	47	33	lipid	lipid	NOUN
dti-2185	47	34	rafts	raft	NOUN
dti-2185	47	35	.	.	PUNCT
dti-2185	48	1	gray	gray	ADJ
dti-2185	48	2	et	et	PROPN
dti-2185	48	3	al	al	PROPN
dti-2185	48	4	treated	treat	VERB
dti-2185	48	5	gpmvs	gpmvs	PROPN
dti-2185	48	6	with	with	ADP
dti-2185	48	7	propofol	propofol	NOUN
dti-2185	48	8	and	and	CCONJ
dti-2185	48	9	its	its	PRON
dti-2185	48	10	structural	structural	ADJ
dti-2185	48	11	analogs	analog	NOUN
dti-2185	48	12	to	to	PART
dti-2185	48	13	examine	examine	VERB
dti-2185	48	14	their	their	PRON
dti-2185	48	15	effects	effect	NOUN
dti-2185	48	16	on	on	ADP
dti-2185	48	17	liquid	liquid	NOUN
dti-2185	48	18	-	-	PUNCT
dti-2185	48	19	liquid	liquid	NOUN
dti-2185	48	20	transition	transition	NOUN
dti-2185	48	21	by	by	ADP
dti-2185	48	22	analyzing	analyze	VERB
dti-2185	48	23	the	the	DET
dti-2185	48	24	lateral	lateral	ADJ
dti-2185	48	25	distribution	distribution	NOUN
dti-2185	48	26	of	of	ADP
dti-2185	48	27	fluorescent	fluorescent	ADJ
dti-2185	48	28	probe	probe	NOUN
dti-2185	48	29	dii	dii	PROPN
dti-2185	48	30	-	-	NOUN
dti-2185	48	31	c12	c12	NOUN
dti-2185	48	32	microscopically	microscopically	NOUN
dti-2185	48	33	(	(	PUNCT
dti-2185	48	34	32	32	NUM
dti-2185	48	35	)	)	PUNCT
dti-2185	48	36	.	.	PUNCT
dti-2185	49	1	propofol	propofol	NOUN
dti-2185	49	2	reduced	reduce	VERB
dti-2185	49	3	the	the	DET
dti-2185	49	4	critical	critical	ADJ
dti-2185	49	5	transition	transition	NOUN
dti-2185	49	6	temperature	temperature	NOUN
dti-2185	49	7	at	at	ADP
dti-2185	49	8	2.5	2.5	NUM
dti-2185	49	9	-	-	SYM
dti-2185	49	10	10	10	NUM
dti-2185	49	11	μm	μm	NOUN
dti-2185	49	12	,	,	PUNCT
dti-2185	49	13	but	but	CCONJ
dti-2185	49	14	not	not	PART
dti-2185	49	15	2,6	2,6	NUM
dti-2185	49	16	-	-	NOUN
dti-2185	49	17	di	di	NOUN
dti-2185	49	18	-	-	PUNCT
dti-2185	49	19	tert	tert	NOUN
dti-2185	49	20	-	-	PUNCT
dti-2185	49	21	butylphenol	butylphenol	NOUN
dti-2185	49	22	without	without	ADP
dti-2185	49	23	the	the	DET
dti-2185	49	24	anesthetic	anesthetic	ADJ
dti-2185	49	25	activity	activity	NOUN
dti-2185	49	26	at	at	ADP
dti-2185	49	27	the	the	DET
dti-2185	49	28	same	same	ADJ
dti-2185	49	29	concentrations	concentration	NOUN
dti-2185	49	30	.	.	PUNCT
dti-2185	50	1	therefore	therefore	ADV
dti-2185	50	2	,	,	PUNCT
dti-2185	50	3	propofol	propofol	NOUN
dti-2185	50	4	is	be	AUX
dti-2185	50	5	considered	consider	VERB
dti-2185	50	6	interaction	interaction	NOUN
dti-2185	50	7	of	of	ADP
dti-2185	50	8	drugs	drug	NOUN
dti-2185	50	9	with	with	ADP
dti-2185	50	10	lipid	lipid	NOUN
dti-2185	50	11	rafts36	rafts36	NOUN
dti-2185	51	1	©	©	PROPN
dti-2185	51	2	2020	2020	NUM
dti-2185	52	1	the	the	DET
dti-2185	52	2	authors	author	NOUN
dti-2185	52	3	.	.	PUNCT
dti-2185	53	1	published	publish	VERB
dti-2185	53	2	by	by	ADP
dti-2185	53	3	aboutscience	aboutscience	NOUN
dti-2185	53	4	to	to	PART
dti-2185	53	5	decrease	decrease	VERB
dti-2185	53	6	the	the	DET
dti-2185	53	7	magnitude	magnitude	NOUN
dti-2185	53	8	of	of	ADP
dti-2185	53	9	membrane	membrane	NOUN
dti-2185	53	10	heterogeneity	heterogeneity	NOUN
dti-2185	53	11	structure	structure	NOUN
dti-2185	53	12	-	-	PUNCT
dti-2185	53	13	specifically	specifically	ADV
dti-2185	53	14	,	,	PUNCT
dti-2185	53	15	affecting	affect	VERB
dti-2185	53	16	receptor	receptor	NOUN
dti-2185	53	17	and	and	CCONJ
dti-2185	53	18	ion	ion	NOUN
dti-2185	53	19	channel	channel	NOUN
dti-2185	53	20	proteins	protein	NOUN
dti-2185	53	21	sensitive	sensitive	ADJ
dti-2185	53	22	to	to	AUX
dti-2185	53	23	raft	raft	NOUN
dti-2185	53	24	heterogeneity	heterogeneity	NOUN
dti-2185	53	25	.	.	PUNCT
dti-2185	54	1	while	while	SCONJ
dti-2185	54	2	propofol	propofol	NOUN
dti-2185	54	3	is	be	AUX
dti-2185	54	4	known	know	VERB
dti-2185	54	5	to	to	PART
dti-2185	54	6	produce	produce	VERB
dti-2185	54	7	bronchodilatation	bronchodilatation	NOUN
dti-2185	54	8	,	,	PUNCT
dti-2185	54	9	the	the	DET
dti-2185	54	10	airway	airway	NOUN
dti-2185	54	11	relaxation	relaxation	NOUN
dti-2185	54	12	involves	involve	VERB
dti-2185	54	13	a	a	DET
dti-2185	54	14	decrease	decrease	NOUN
dti-2185	54	15	of	of	ADP
dti-2185	54	16	ca2	ca2	PROPN
dti-2185	54	17	+	+	PROPN
dti-2185	54	18	concentrations	concentration	NOUN
dti-2185	54	19	in	in	ADP
dti-2185	54	20	airway	airway	NOUN
dti-2185	54	21	smooth	smooth	ADJ
dti-2185	54	22	muscle	muscle	NOUN
dti-2185	54	23	cells	cell	NOUN
dti-2185	54	24	that	that	PRON
dti-2185	54	25	are	be	AUX
dti-2185	54	26	regulated	regulate	VERB
dti-2185	54	27	by	by	ADP
dti-2185	54	28	caveolae	caveolae	NOUN
dti-2185	54	29	.	.	PUNCT
dti-2185	55	1	by	by	ADP
dti-2185	55	2	exposing	expose	VERB
dti-2185	55	3	human	human	ADJ
dti-2185	55	4	airway	airway	NOUN
dti-2185	55	5	smooth	smooth	ADJ
dti-2185	55	6	muscle	muscle	NOUN
dti-2185	55	7	cells	cell	NOUN
dti-2185	55	8	to	to	ADP
dti-2185	55	9	propofol	propofol	VERB
dti-2185	55	10	at	at	ADP
dti-2185	55	11	10	10	NUM
dti-2185	55	12	and	and	CCONJ
dti-2185	55	13	30	30	NUM
dti-2185	55	14	μm	μm	NOUN
dti-2185	55	15	,	,	PUNCT
dti-2185	55	16	grim	grim	ADJ
dti-2185	55	17	et	et	PROPN
dti-2185	55	18	al	al	PROPN
dti-2185	55	19	found	find	VERB
dti-2185	55	20	that	that	SCONJ
dti-2185	55	21	propofol	propofol	NOUN
dti-2185	55	22	increases	increase	VERB
dti-2185	55	23	in	in	ADP
dti-2185	55	24	membrane	membrane	NOUN
dti-2185	55	25	caveolae	caveolae	NOUN
dti-2185	55	26	and	and	CCONJ
dti-2185	55	27	reduces	reduce	VERB
dti-2185	55	28	the	the	DET
dti-2185	55	29	intracellular	intracellular	ADJ
dti-2185	55	30	ca2	ca2	NOUN
dti-2185	55	31	+	+	CCONJ
dti-2185	55	32	concentration	concentration	NOUN
dti-2185	55	33	response	response	NOUN
dti-2185	55	34	to	to	ADP
dti-2185	55	35	10	10	NUM
dti-2185	55	36	μm	μm	NOUN
dti-2185	55	37	histamine	histamine	NOUN
dti-2185	55	38	(	(	PUNCT
dti-2185	55	39	33	33	NUM
dti-2185	55	40	)	)	PUNCT
dti-2185	55	41	.	.	PUNCT
dti-2185	56	1	they	they	PRON
dti-2185	56	2	also	also	ADV
dti-2185	56	3	suggested	suggest	VERB
dti-2185	56	4	that	that	SCONJ
dti-2185	56	5	propofol	propofol	NOUN
dti-2185	56	6	may	may	AUX
dti-2185	56	7	induce	induce	VERB
dti-2185	56	8	caveolar	caveolar	ADJ
dti-2185	56	9	disruption	disruption	NOUN
dti-2185	56	10	and	and	CCONJ
dti-2185	56	11	caveolin-1	caveolin-1	NUM
dti-2185	56	12	expression	expression	NOUN
dti-2185	56	13	decrease	decrease	NOUN
dti-2185	56	14	.	.	PUNCT
dti-2185	57	1	inhalational	inhalational	ADJ
dti-2185	57	2	anesthetics	anesthetic	NOUN
dti-2185	57	3	patel	patel	PROPN
dti-2185	57	4	et	et	PROPN
dti-2185	57	5	al	al	PROPN
dti-2185	57	6	investigated	investigate	VERB
dti-2185	57	7	the	the	DET
dti-2185	57	8	membrane	membrane	NOUN
dti-2185	57	9	effects	effect	NOUN
dti-2185	57	10	of	of	ADP
dti-2185	57	11	isoflurane	isoflurane	NOUN
dti-2185	57	12	using	use	VERB
dti-2185	57	13	different	different	ADJ
dti-2185	57	14	membrane	membrane	NOUN
dti-2185	57	15	systems	system	NOUN
dti-2185	57	16	such	such	ADJ
dti-2185	57	17	as	as	ADP
dti-2185	57	18	popc	popc	NOUN
dti-2185	57	19	/	/	SYM
dti-2185	57	20	cholesterol	cholesterol	NOUN
dti-2185	57	21	liposomal	liposomal	ADJ
dti-2185	57	22	membranes	membrane	NOUN
dti-2185	57	23	,	,	PUNCT
dti-2185	57	24	erythrocyte	erythrocyte	ADJ
dti-2185	57	25	ghosts	ghost	NOUN
dti-2185	57	26	and	and	CCONJ
dti-2185	57	27	brain	brain	NOUN
dti-2185	57	28	endothelial	endothelial	ADJ
dti-2185	57	29	cell	cell	NOUN
dti-2185	57	30	-	-	PUNCT
dti-2185	57	31	mimetic	mimetic	ADJ
dti-2185	57	32	membranes	membrane	NOUN
dti-2185	57	33	(	(	PUNCT
dti-2185	57	34	34	34	NUM
dti-2185	57	35	)	)	PUNCT
dti-2185	57	36	.	.	PUNCT
dti-2185	58	1	fa	fa	PROPN
dti-2185	58	2	measurements	measurement	NOUN
dti-2185	58	3	indicated	indicate	VERB
dti-2185	58	4	that	that	SCONJ
dti-2185	58	5	isoflurane	isoflurane	NOUN
dti-2185	58	6	increases	increase	VERB
dti-2185	58	7	the	the	DET
dti-2185	58	8	membrane	membrane	NOUN
dti-2185	58	9	fluidity	fluidity	NOUN
dti-2185	58	10	at	at	ADP
dti-2185	58	11	1	1	NUM
dti-2185	58	12	and	and	CCONJ
dti-2185	58	13	5	5	NUM
dti-2185	58	14	mm	mm	NOUN
dti-2185	58	15	.	.	PUNCT
dti-2185	59	1	turkyilmaz	turkyilmaz	NOUN
dti-2185	59	2	et	et	PROPN
dti-2185	59	3	al	al	PROPN
dti-2185	59	4	prepared	prepare	VERB
dti-2185	59	5	large	large	ADJ
dti-2185	59	6	unilamellar	unilamellar	ADJ
dti-2185	59	7	vesicles	vesicle	NOUN
dti-2185	59	8	(	(	PUNCT
dti-2185	59	9	luvs	luvs	NOUN
dti-2185	59	10	)	)	PUNCT
dti-2185	59	11	with	with	ADP
dti-2185	59	12	1,2	1,2	NUM
dti-2185	59	13	-	-	ADJ
dti-2185	59	14	dipalmitoylphosphatidylcholine	dipalmitoylphosphatidylcholine	ADJ
dti-2185	59	15	(	(	PUNCT
dti-2185	59	16	dppc	dppc	NOUN
dti-2185	59	17	)	)	PUNCT
dti-2185	59	18	and	and	CCONJ
dti-2185	59	19	cholesterol	cholesterol	NOUN
dti-2185	59	20	to	to	PART
dti-2185	59	21	be	be	AUX
dti-2185	59	22	2.5	2.5	NUM
dti-2185	59	23	mol%	mol%	NOUN
dti-2185	59	24	or	or	CCONJ
dti-2185	59	25	37.5	37.5	NUM
dti-2185	59	26	mol%	mol%	PROPN
dti-2185	59	27	cholesterol	cholesterol	NOUN
dti-2185	59	28	containing	contain	VERB
dti-2185	59	29	dppc	dppc	NOUN
dti-2185	59	30	membranes	membrane	NOUN
dti-2185	59	31	to	to	PART
dti-2185	59	32	verify	verify	VERB
dti-2185	59	33	the	the	DET
dti-2185	59	34	membrane	membrane	NOUN
dti-2185	59	35	effects	effect	NOUN
dti-2185	59	36	of	of	ADP
dti-2185	59	37	inhalational	inhalational	ADJ
dti-2185	59	38	anesthetics	anesthetic	NOUN
dti-2185	59	39	(	(	PUNCT
dti-2185	59	40	35	35	NUM
dti-2185	59	41	)	)	PUNCT
dti-2185	59	42	.	.	PUNCT
dti-2185	60	1	isoflurane	isoflurane	ADJ
dti-2185	60	2	and	and	CCONJ
dti-2185	60	3	halothane	halothane	NOUN
dti-2185	60	4	weakened	weaken	VERB
dti-2185	60	5	and	and	CCONJ
dti-2185	60	6	strengthened	strengthen	VERB
dti-2185	60	7	the	the	DET
dti-2185	60	8	sterol	sterol	NOUN
dti-2185	60	9	-	-	PUNCT
dti-2185	60	10	phospholipid	phospholipid	NOUN
dti-2185	60	11	association	association	NOUN
dti-2185	60	12	in	in	ADP
dti-2185	60	13	cholesterol	cholesterol	NOUN
dti-2185	60	14	-	-	PUNCT
dti-2185	60	15	rich	rich	ADJ
dti-2185	60	16	lo	lo	NOUN
dti-2185	60	17	phase	phase	NOUN
dti-2185	60	18	membranes	membrane	NOUN
dti-2185	60	19	and	and	CCONJ
dti-2185	60	20	in	in	ADP
dti-2185	60	21	cholesterol	cholesterol	NOUN
dti-2185	60	22	-	-	PUNCT
dti-2185	60	23	poor	poor	ADJ
dti-2185	60	24	ld	ld	NOUN
dti-2185	60	25	phase	phase	NOUN
dti-2185	60	26	membranes	membrane	NOUN
dti-2185	60	27	,	,	PUNCT
dti-2185	60	28	respectively	respectively	ADV
dti-2185	60	29	,	,	PUNCT
dti-2185	60	30	at	at	ADP
dti-2185	60	31	2.5	2.5	NUM
dti-2185	60	32	-	-	SYM
dti-2185	60	33	12	12	NUM
dti-2185	60	34	mm	mm	NOUN
dti-2185	60	35	.	.	PUNCT
dti-2185	61	1	in	in	ADP
dti-2185	61	2	nd	nd	ADP
dti-2185	61	3	and	and	CCONJ
dti-2185	61	4	xd	xd	ADV
dti-2185	61	5	experiments	experiment	NOUN
dti-2185	61	6	of	of	ADP
dti-2185	61	7	weinrich	weinrich	PROPN
dti-2185	61	8	et	et	PROPN
dti-2185	61	9	al	al	PROPN
dti-2185	61	10	,	,	PUNCT
dti-2185	61	11	halothane	halothane	PROPN
dti-2185	61	12	was	be	AUX
dti-2185	61	13	subjected	subject	VERB
dti-2185	61	14	to	to	ADP
dti-2185	61	15	the	the	DET
dti-2185	61	16	reaction	reaction	NOUN
dti-2185	61	17	with	with	ADP
dti-2185	61	18	multilayer	multilayer	ADJ
dti-2185	61	19	membranes	membrane	NOUN
dti-2185	61	20	that	that	PRON
dti-2185	61	21	were	be	AUX
dti-2185	61	22	prepared	prepare	VERB
dti-2185	61	23	with	with	ADP
dti-2185	61	24	an	an	DET
dti-2185	61	25	equimolar	equimolar	NOUN
dti-2185	61	26	mixture	mixture	NOUN
dti-2185	61	27	of	of	ADP
dti-2185	61	28	dppc	dppc	NOUN
dti-2185	61	29	and	and	CCONJ
dti-2185	61	30	1,2	1,2	NUM
dti-2185	61	31	-	-	NUM
dti-2185	61	32	dilauroylphosphatidylcholine	dilauroylphosphatidylcholine	ADJ
dti-2185	61	33	(	(	PUNCT
dti-2185	61	34	dlpc	dlpc	NOUN
dti-2185	61	35	)	)	PUNCT
dti-2185	61	36	to	to	PART
dti-2185	61	37	form	form	VERB
dti-2185	61	38	distinct	distinct	ADJ
dti-2185	61	39	dppc	dppc	NOUN
dti-2185	61	40	-	-	PUNCT
dti-2185	61	41	rich	rich	ADJ
dti-2185	61	42	ordered	order	VERB
dti-2185	61	43	and	and	CCONJ
dti-2185	61	44	dlpc	dlpc	NOUN
dti-2185	61	45	-	-	PUNCT
dti-2185	61	46	rich	rich	ADJ
dti-2185	61	47	fluid	fluid	NOUN
dti-2185	61	48	phase	phase	NOUN
dti-2185	61	49	(	(	PUNCT
dti-2185	61	50	36	36	NUM
dti-2185	61	51	)	)	PUNCT
dti-2185	61	52	.	.	PUNCT
dti-2185	62	1	halothane	halothane	PROPN
dti-2185	62	2	reduced	reduce	VERB
dti-2185	62	3	the	the	DET
dti-2185	62	4	transition	transition	NOUN
dti-2185	62	5	temperature	temperature	NOUN
dti-2185	62	6	by	by	ADP
dti-2185	62	7	about	about	ADV
dti-2185	62	8	5	5	NUM
dti-2185	62	9	°	°	NOUN
dti-2185	62	10	c	c	NOUN
dti-2185	62	11	at	at	ADP
dti-2185	62	12	1.5	1.5	NUM
dti-2185	62	13	mol%	mol%	PROPN
dti-2185	62	14	corresponding	correspond	VERB
dti-2185	62	15	to	to	ADP
dti-2185	62	16	about	about	ADP
dti-2185	62	17	twice	twice	DET
dti-2185	62	18	the	the	DET
dti-2185	62	19	minimum	minimum	ADJ
dti-2185	62	20	alveolar	alveolar	ADJ
dti-2185	62	21	concentration	concentration	NOUN
dti-2185	62	22	(	(	PUNCT
dti-2185	62	23	mac	mac	PROPN
dti-2185	62	24	)	)	PUNCT
dti-2185	62	25	for	for	ADP
dti-2185	62	26	human	human	ADJ
dti-2185	62	27	anesthesia	anesthesia	PROPN
dti-2185	62	28	,	,	PUNCT
dti-2185	62	29	but	but	CCONJ
dti-2185	62	30	not	not	PART
dti-2185	62	31	non	non	ADJ
dti-2185	62	32	-	-	ADJ
dti-2185	62	33	anesthetic	anesthetic	ADJ
dti-2185	62	34	table	table	NOUN
dti-2185	62	35	i	i	PRON
dti-2185	62	36	interaction	interaction	NOUN
dti-2185	62	37	of	of	ADP
dti-2185	62	38	general	general	ADJ
dti-2185	62	39	anesthetics	anesthetic	NOUN
dti-2185	62	40	with	with	ADP
dti-2185	62	41	lipid	lipid	NOUN
dti-2185	62	42	raft	raft	NOUN
dti-2185	62	43	membrane	membrane	NOUN
dti-2185	62	44	domains	domain	NOUN
dti-2185	62	45	and	and	CCONJ
dti-2185	62	46	membranes	membrane	NOUN
dti-2185	62	47	drug	drug	NOUN
dti-2185	62	48	class	class	NOUN
dti-2185	62	49	drug	drug	NOUN
dti-2185	62	50	membrane	membrane	NOUN
dti-2185	62	51	induced	induce	VERB
dti-2185	62	52	membrane	membrane	NOUN
dti-2185	62	53	modification	modification	NOUN
dti-2185	62	54	reference	reference	NOUN
dti-2185	62	55	intravenous	intravenous	ADJ
dti-2185	62	56	anesthetic	anesthetic	ADJ
dti-2185	62	57	propofol	propofol	NOUN
dti-2185	62	58	(	(	PUNCT
dti-2185	62	59	0.125	0.125	NUM
dti-2185	62	60	-	-	SYM
dti-2185	62	61	1.0	1.0	NUM
dti-2185	62	62	μm	μm	NUM
dti-2185	62	63	)	)	PUNCT
dti-2185	62	64	binary	binary	ADJ
dti-2185	62	65	liposomal	liposomal	ADJ
dti-2185	62	66	membranes	membrane	NOUN
dti-2185	62	67	(	(	PUNCT
dti-2185	62	68	80	80	NUM
dti-2185	62	69	mol%	mol%	PROPN
dti-2185	62	70	popc	popc	NOUN
dti-2185	62	71	and	and	CCONJ
dti-2185	62	72	20	20	NUM
dti-2185	62	73	mol%	mol%	PROPN
dti-2185	62	74	cholesterol	cholesterol	NOUN
dti-2185	62	75	)	)	PUNCT
dti-2185	62	76	increased	increase	VERB
dti-2185	62	77	membrane	membrane	NOUN
dti-2185	62	78	fluidity	fluidity	NOUN
dti-2185	62	79	30	30	NUM
dti-2185	62	80	intravenous	intravenous	ADJ
dti-2185	62	81	anesthetic	anesthetic	ADJ
dti-2185	62	82	propofol	propofol	NOUN
dti-2185	62	83	(	(	PUNCT
dti-2185	62	84	10	10	NUM
dti-2185	62	85	μm	μm	NOUN
dti-2185	62	86	)	)	PUNCT
dti-2185	62	87	quinary	quinary	ADJ
dti-2185	62	88	liposomal	liposomal	ADJ
dti-2185	62	89	membranes	membrane	NOUN
dti-2185	62	90	(	(	PUNCT
dti-2185	62	91	55	55	NUM
dti-2185	62	92	mol%	mol%	PROPN
dti-2185	62	93	phospholipids	phospholipid	NOUN
dti-2185	62	94	(	(	PUNCT
dti-2185	62	95	popc	popc	NOUN
dti-2185	62	96	,	,	PUNCT
dti-2185	62	97	sm	sm	PROPN
dti-2185	62	98	,	,	PUNCT
dti-2185	62	99	pope	pope	NOUN
dti-2185	62	100	and	and	CCONJ
dti-2185	62	101	pops	pop	NOUN
dti-2185	62	102	)	)	PUNCT
dti-2185	62	103	and	and	CCONJ
dti-2185	62	104	45	45	NUM
dti-2185	62	105	mol%	mol%	PROPN
dti-2185	62	106	cholesterol	cholesterol	NOUN
dti-2185	62	107	)	)	PUNCT
dti-2185	62	108	increased	increase	VERB
dti-2185	62	109	membrane	membrane	NOUN
dti-2185	62	110	fluidity	fluidity	NOUN
dti-2185	62	111	31	31	NUM
dti-2185	62	112	intravenous	intravenous	ADJ
dti-2185	62	113	anesthetic	anesthetic	ADJ
dti-2185	62	114	propofol	propofol	NOUN
dti-2185	62	115	(	(	PUNCT
dti-2185	62	116	2.5	2.5	NUM
dti-2185	62	117	-	-	SYM
dti-2185	62	118	10	10	NUM
dti-2185	62	119	μm	μm	NUM
dti-2185	62	120	)	)	PUNCT
dti-2185	62	121	gpmvs	gpmvs	NOUN
dti-2185	62	122	isolated	isolate	VERB
dti-2185	62	123	from	from	ADP
dti-2185	62	124	rat	rat	NOUN
dti-2185	62	125	basophil	basophil	NOUN
dti-2185	62	126	leukemia	leukemia	NOUN
dti-2185	62	127	cells	cell	NOUN
dti-2185	62	128	reduced	reduce	VERB
dti-2185	62	129	the	the	DET
dti-2185	62	130	critical	critical	ADJ
dti-2185	62	131	transition	transition	NOUN
dti-2185	62	132	temperature	temperature	NOUN
dti-2185	62	133	structure	structure	NOUN
dti-2185	62	134	-	-	PUNCT
dti-2185	62	135	specifically	specifically	ADV
dti-2185	62	136	32	32	NUM
dti-2185	62	137	intravenous	intravenous	ADJ
dti-2185	62	138	anesthetic	anesthetic	ADJ
dti-2185	62	139	propofol	propofol	NOUN
dti-2185	62	140	(	(	PUNCT
dti-2185	62	141	10	10	NUM
dti-2185	62	142	and	and	CCONJ
dti-2185	62	143	30	30	NUM
dti-2185	62	144	μm	μm	NUM
dti-2185	62	145	)	)	PUNCT
dti-2185	62	146	human	human	ADJ
dti-2185	62	147	airway	airway	NOUN
dti-2185	62	148	smooth	smooth	ADJ
dti-2185	62	149	muscle	muscle	NOUN
dti-2185	62	150	cell	cell	NOUN
dti-2185	62	151	membranes	membrane	NOUN
dti-2185	62	152	reduced	reduce	VERB
dti-2185	62	153	the	the	DET
dti-2185	62	154	intracellular	intracellular	ADJ
dti-2185	62	155	ca2	ca2	PROPN
dti-2185	62	156	+	+	CCONJ
dti-2185	62	157	concentration	concentration	NOUN
dti-2185	62	158	responses	response	NOUN
dti-2185	62	159	to	to	ADP
dti-2185	62	160	10	10	NUM
dti-2185	62	161	μm	μm	NUM
dti-2185	62	162	histamine	histamine	NOUN
dti-2185	62	163	,	,	PUNCT
dti-2185	62	164	disrupted	disrupt	VERB
dti-2185	62	165	caveolae	caveolae	NOUN
dti-2185	62	166	and	and	CCONJ
dti-2185	62	167	decreased	decrease	VERB
dti-2185	62	168	caveolin-1	caveolin-1	NUM
dti-2185	62	169	expression	expression	NOUN
dti-2185	62	170	33	33	NUM
dti-2185	62	171	inhalational	inhalational	ADJ
dti-2185	62	172	anesthetic	anesthetic	NOUN
dti-2185	62	173	isoflurane	isoflurane	NOUN
dti-2185	62	174	(	(	PUNCT
dti-2185	62	175	1	1	NUM
dti-2185	62	176	and	and	CCONJ
dti-2185	62	177	5	5	NUM
dti-2185	62	178	mm	mm	NOUN
dti-2185	62	179	)	)	PUNCT
dti-2185	62	180	popc	popc	PROPN
dti-2185	62	181	/	/	SYM
dti-2185	62	182	cholesterol	cholesterol	NOUN
dti-2185	62	183	liposomal	liposomal	ADJ
dti-2185	62	184	membranes	membrane	NOUN
dti-2185	62	185	,	,	PUNCT
dti-2185	62	186	erythrocyte	erythrocyte	ADJ
dti-2185	62	187	ghosts	ghost	NOUN
dti-2185	62	188	and	and	CCONJ
dti-2185	62	189	brain	brain	NOUN
dti-2185	62	190	endothelial	endothelial	ADJ
dti-2185	62	191	cell	cell	NOUN
dti-2185	62	192	-	-	PUNCT
dti-2185	62	193	mimetic	mimetic	ADJ
dti-2185	62	194	membranes	membrane	NOUN
dti-2185	62	195	increased	increase	VERB
dti-2185	62	196	membrane	membrane	NOUN
dti-2185	62	197	fluidity	fluidity	NOUN
dti-2185	62	198	34	34	NUM
dti-2185	62	199	inhalational	inhalational	ADJ
dti-2185	62	200	anesthetic	anesthetic	NOUN
dti-2185	62	201	isoflurane	isoflurane	NOUN
dti-2185	62	202	(	(	PUNCT
dti-2185	62	203	2.5	2.5	NUM
dti-2185	62	204	-	-	SYM
dti-2185	62	205	12	12	NUM
dti-2185	62	206	mm	mm	NOUN
dti-2185	62	207	)	)	PUNCT
dti-2185	62	208	luvs	luvs	NOUN
dti-2185	62	209	(	(	PUNCT
dti-2185	62	210	62.5	62.5	NUM
dti-2185	62	211	mol%	mol%	PROPN
dti-2185	62	212	dppc	dppc	NOUN
dti-2185	62	213	and	and	CCONJ
dti-2185	62	214	37.5	37.5	NUM
dti-2185	62	215	mol%	mol%	PROPN
dti-2185	62	216	cholesterol	cholesterol	NOUN
dti-2185	62	217	)	)	PUNCT
dti-2185	62	218	weakened	weaken	VERB
dti-2185	62	219	the	the	DET
dti-2185	62	220	sterol	sterol	NOUN
dti-2185	62	221	-	-	PUNCT
dti-2185	62	222	phospholipid	phospholipid	NOUN
dti-2185	62	223	association	association	NOUN
dti-2185	62	224	in	in	ADP
dti-2185	62	225	cholesterol	cholesterol	NOUN
dti-2185	62	226	-	-	PUNCT
dti-2185	62	227	rich	rich	ADJ
dti-2185	62	228	lo	lo	NOUN
dti-2185	62	229	phase	phase	NOUN
dti-2185	62	230	membranes	membrane	VERB
dti-2185	62	231	35	35	NUM
dti-2185	62	232	inhalational	inhalational	ADJ
dti-2185	62	233	anesthetic	anesthetic	ADJ
dti-2185	62	234	halothane	halothane	NOUN
dti-2185	62	235	(	(	PUNCT
dti-2185	62	236	1.5	1.5	NUM
dti-2185	62	237	mol%	mol%	NOUN
dti-2185	62	238	)	)	PUNCT
dti-2185	62	239	multilayer	multilayer	ADJ
dti-2185	62	240	membranes	membrane	NOUN
dti-2185	62	241	(	(	PUNCT
dti-2185	62	242	dppc	dppc	NOUN
dti-2185	62	243	and	and	CCONJ
dti-2185	62	244	dlpc	dlpc	NOUN
dti-2185	62	245	,	,	PUNCT
dti-2185	62	246	1:1	1:1	NUM
dti-2185	62	247	molar	molar	ADJ
dti-2185	62	248	ratio	ratio	NOUN
dti-2185	62	249	)	)	PUNCT
dti-2185	62	250	reduced	reduce	VERB
dti-2185	62	251	the	the	DET
dti-2185	62	252	transition	transition	NOUN
dti-2185	62	253	temperature	temperature	NOUN
dti-2185	62	254	by	by	ADP
dti-2185	62	255	about	about	ADV
dti-2185	62	256	5	5	NUM
dti-2185	62	257	°	°	ADP
dti-2185	62	258	c	c	NOUN
dti-2185	62	259	36	36	NUM
dti-2185	62	260	inhalational	inhalational	ADJ
dti-2185	62	261	anesthetic	anesthetic	NOUN
dti-2185	62	262	xenon	xenon	NOUN
dti-2185	62	263	(	(	PUNCT
dti-2185	62	264	4.6	4.6	NUM
dti-2185	62	265	-	-	ADJ
dti-2185	62	266	fold	fold	ADJ
dti-2185	62	267	mac	mac	NOUN
dti-2185	62	268	)	)	PUNCT
dti-2185	62	269	nitrous	nitrous	ADJ
dti-2185	62	270	oxide	oxide	NOUN
dti-2185	62	271	(	(	PUNCT
dti-2185	62	272	4.6	4.6	NUM
dti-2185	62	273	-	-	ADJ
dti-2185	62	274	fold	fold	ADJ
dti-2185	62	275	mac	mac	PROPN
dti-2185	62	276	)	)	PUNCT
dti-2185	62	277	halothane	halothane	NOUN
dti-2185	62	278	(	(	PUNCT
dti-2185	62	279	threeto	threeto	PROPN
dti-2185	62	280	fivefold	fivefold	PROPN
dti-2185	62	281	mac	mac	PROPN
dti-2185	62	282	)	)	PUNCT
dti-2185	62	283	isoflurane	isoflurane	NOUN
dti-2185	62	284	(	(	PUNCT
dti-2185	62	285	three	three	NUM
dti-2185	62	286	to	to	ADP
dti-2185	62	287	fivefold	fivefold	ADJ
dti-2185	62	288	mac	mac	PROPN
dti-2185	62	289	)	)	PUNCT
dti-2185	62	290	raft	raft	NOUN
dti-2185	62	291	model	model	NOUN
dti-2185	62	292	membranes	membrane	NOUN
dti-2185	62	293	(	(	PUNCT
dti-2185	62	294	dopc	dopc	NOUN
dti-2185	62	295	,	,	PUNCT
dti-2185	62	296	sm	sm	PROPN
dti-2185	62	297	and	and	CCONJ
dti-2185	62	298	cholesterol	cholesterol	NOUN
dti-2185	62	299	,	,	PUNCT
dti-2185	62	300	1:1:0.2	1:1:0.2	NUM
dti-2185	62	301	molar	molar	ADJ
dti-2185	62	302	ratio	ratio	NOUN
dti-2185	62	303	)	)	PUNCT
dti-2185	62	304	increased	increase	VERB
dti-2185	62	305	the	the	DET
dti-2185	62	306	ld	ld	NOUN
dti-2185	62	307	phase	phase	NOUN
dti-2185	62	308	decreased	decrease	VERB
dti-2185	62	309	the	the	DET
dti-2185	62	310	relative	relative	ADJ
dti-2185	62	311	intensity	intensity	NOUN
dti-2185	62	312	of	of	ADP
dti-2185	62	313	lo	lo	PROPN
dti-2185	62	314	to	to	ADP
dti-2185	62	315	ld	ld	PROPN
dti-2185	62	316	phase	phase	NOUN
dti-2185	62	317	37	37	NUM
dti-2185	62	318	barbiturate	barbiturate	NOUN
dti-2185	62	319	rats	rat	NOUN
dti-2185	62	320	injected	inject	VERB
dti-2185	62	321	with	with	ADP
dti-2185	62	322	sodium	sodium	NOUN
dti-2185	62	323	pentobarbital	pentobarbital	NOUN
dti-2185	62	324	(	(	PUNCT
dti-2185	62	325	50	50	NUM
dti-2185	62	326	mg	mg	PROPN
dti-2185	62	327	/	/	SYM
dti-2185	62	328	kg	kg	PROPN
dti-2185	62	329	,	,	PUNCT
dti-2185	62	330	i.p	i.p	PROPN
dti-2185	62	331	.	.	PUNCT
dti-2185	62	332	)	)	PUNCT
dti-2185	63	1	lipid	lipid	NOUN
dti-2185	63	2	rafts	raft	NOUN
dti-2185	63	3	isolated	isolate	VERB
dti-2185	63	4	from	from	ADP
dti-2185	63	5	rat	rat	NOUN
dti-2185	63	6	brains	brain	NOUN
dti-2185	63	7	15	15	NUM
dti-2185	63	8	minutes	minute	NOUN
dti-2185	63	9	after	after	SCONJ
dti-2185	63	10	drug	drug	NOUN
dti-2185	63	11	injection	injection	NOUN
dti-2185	63	12	reduced	reduce	VERB
dti-2185	63	13	the	the	DET
dti-2185	63	14	transition	transition	NOUN
dti-2185	63	15	temperature	temperature	NOUN
dti-2185	63	16	38	38	NUM
dti-2185	63	17	dlpc	dlpc	NOUN
dti-2185	63	18	=	=	NOUN
dti-2185	63	19	1,2	1,2	NUM
dti-2185	63	20	-	-	NUM
dti-2185	63	21	dilauroylphosphatidylcholine	dilauroylphosphatidylcholine	ADJ
dti-2185	63	22	;	;	PUNCT
dti-2185	63	23	dopc	dopc	NOUN
dti-2185	63	24	=	=	SYM
dti-2185	63	25	1,2	1,2	NUM
dti-2185	63	26	-	-	PUNCT
dti-2185	63	27	dioleoylphosphatidylcholine	dioleoylphosphatidylcholine	NOUN
dti-2185	63	28	;	;	PUNCT
dti-2185	63	29	dppc	dppc	NOUN
dti-2185	63	30	=	=	SYM
dti-2185	63	31	1,2	1,2	NUM
dti-2185	63	32	-	-	NUM
dti-2185	63	33	dipalmitoylphosphatidylcholine	dipalmitoylphosphatidylcholine	NOUN
dti-2185	63	34	;	;	PUNCT
dti-2185	63	35	gpmv	gpmv	X
dti-2185	63	36	=	=	SYM
dti-2185	63	37	giant	giant	ADJ
dti-2185	63	38	plasma	plasma	NOUN
dti-2185	63	39	membrane	membrane	NOUN
dti-2185	63	40	vesicle	vesicle	NOUN
dti-2185	63	41	;	;	PUNCT
dti-2185	63	42	luv	luv	NOUN
dti-2185	63	43	=	=	PROPN
dti-2185	63	44	large	large	ADJ
dti-2185	63	45	unilamellar	unilamellar	ADJ
dti-2185	63	46	vesicle	vesicle	NOUN
dti-2185	63	47	;	;	PUNCT
dti-2185	63	48	mac	mac	NOUN
dti-2185	63	49	=	=	SYM
dti-2185	63	50	minimum	minimum	ADJ
dti-2185	63	51	alveolar	alveolar	ADJ
dti-2185	63	52	concentration	concentration	NOUN
dti-2185	63	53	;	;	PUNCT
dti-2185	63	54	popc	popc	NOUN
dti-2185	63	55	=	=	SYM
dti-2185	63	56	1	1	NUM
dti-2185	63	57	-	-	PUNCT
dti-2185	63	58	palmitoyl-2	palmitoyl-2	VERB
dti-2185	63	59	-	-	PUNCT
dti-2185	63	60	oleoylphosphatidylcholine	oleoylphosphatidylcholine	NOUN
dti-2185	63	61	;	;	PUNCT
dti-2185	63	62	pope	pope	NOUN
dti-2185	63	63	=	=	SYM
dti-2185	63	64	1	1	NUM
dti-2185	63	65	-	-	PUNCT
dti-2185	63	66	palmitoyl2	palmitoyl2	NOUN
dti-2185	63	67	-	-	PUNCT
dti-2185	63	68	oleoylphosphatidylethanolamine	oleoylphosphatidylethanolamine	NOUN
dti-2185	63	69	;	;	PUNCT
dti-2185	63	70	pops	pop	NOUN
dti-2185	63	71	=	=	SYM
dti-2185	63	72	1	1	NUM
dti-2185	63	73	-	-	PUNCT
dti-2185	63	74	palmitoyl-2	palmitoyl-2	VERB
dti-2185	63	75	-	-	PUNCT
dti-2185	63	76	oleoylphosphatidylserine	oleoylphosphatidylserine	ADJ
dti-2185	63	77	;	;	PUNCT
dti-2185	63	78	sm	sm	PROPN
dti-2185	63	79	=	=	VERB
dti-2185	63	80	sphingomyelin	sphingomyelin	NOUN
dti-2185	63	81	.	.	PUNCT
dti-2185	64	1	tsuchiya	tsuchiya	PROPN
dti-2185	64	2	and	and	CCONJ
dti-2185	64	3	mizogami	mizogami	PROPN
dti-2185	64	4	37	37	NUM
dti-2185	64	5	©	©	PROPN
dti-2185	64	6	2020	2020	NUM
dti-2185	64	7	the	the	DET
dti-2185	64	8	authors	author	NOUN
dti-2185	64	9	.	.	PUNCT
dti-2185	65	1	published	publish	VERB
dti-2185	65	2	by	by	ADP
dti-2185	65	3	aboutscience	aboutscience	NOUN
dti-2185	65	4	1,2	1,2	NUM
dti-2185	65	5	-	-	NOUN
dti-2185	65	6	dichlorohexafluorocyclobutane	dichlorohexafluorocyclobutane	NOUN
dti-2185	65	7	even	even	ADV
dti-2185	65	8	at	at	ADP
dti-2185	65	9	fivefold	fivefold	PROPN
dti-2185	65	10	mac	mac	PROPN
dti-2185	65	11	.	.	PROPN
dti-2185	66	1	weinrich	weinrich	PROPN
dti-2185	66	2	and	and	CCONJ
dti-2185	66	3	worcester	worcester	PROPN
dti-2185	66	4	determined	determine	VERB
dti-2185	66	5	the	the	DET
dti-2185	66	6	effects	effect	NOUN
dti-2185	66	7	of	of	ADP
dti-2185	66	8	different	different	ADJ
dti-2185	66	9	anesthetics	anesthetic	NOUN
dti-2185	66	10	on	on	ADP
dti-2185	66	11	liquid	liquid	ADJ
dti-2185	66	12	phase	phase	NOUN
dti-2185	66	13	distribution	distribution	NOUN
dti-2185	66	14	in	in	ADP
dti-2185	66	15	raft	raft	NOUN
dti-2185	66	16	model	model	NOUN
dti-2185	66	17	membranes	membrane	NOUN
dti-2185	66	18	prepared	prepare	VERB
dti-2185	66	19	with	with	ADP
dti-2185	66	20	1,2	1,2	NUM
dti-2185	66	21	-	-	NOUN
dti-2185	66	22	dioleoylphosphatidylcholine	dioleoylphosphatidylcholine	NOUN
dti-2185	66	23	(	(	PUNCT
dti-2185	66	24	dopc	dopc	NOUN
dti-2185	66	25	)	)	PUNCT
dti-2185	66	26	,	,	PUNCT
dti-2185	66	27	sm	sm	PROPN
dti-2185	66	28	and	and	CCONJ
dti-2185	66	29	cholesterol	cholesterol	NOUN
dti-2185	66	30	(	(	PUNCT
dti-2185	66	31	1:1:0.2	1:1:0.2	NUM
dti-2185	66	32	molar	molar	ADJ
dti-2185	66	33	ratio	ratio	NOUN
dti-2185	66	34	)	)	PUNCT
dti-2185	66	35	by	by	ADP
dti-2185	66	36	nd	nd	ADV
dti-2185	66	37	and	and	CCONJ
dti-2185	66	38	xd	xd	INTJ
dti-2185	66	39	analysis	analysis	NOUN
dti-2185	66	40	(	(	PUNCT
dti-2185	66	41	37	37	NUM
dti-2185	66	42	)	)	PUNCT
dti-2185	66	43	.	.	PUNCT
dti-2185	67	1	xenon	xenon	NOUN
dti-2185	67	2	and	and	CCONJ
dti-2185	67	3	nitrous	nitrous	ADJ
dti-2185	67	4	oxide	oxide	NOUN
dti-2185	67	5	increased	increase	VERB
dti-2185	67	6	the	the	DET
dti-2185	67	7	ld	ld	NOUN
dti-2185	67	8	phase	phase	NOUN
dti-2185	67	9	at	at	ADP
dti-2185	67	10	4.6	4.6	NUM
dti-2185	67	11	-	-	ADJ
dti-2185	67	12	fold	fold	ADJ
dti-2185	67	13	mac	mac	PROPN
dti-2185	67	14	,	,	PUNCT
dti-2185	67	15	and	and	CCONJ
dti-2185	67	16	halothane	halothane	ADJ
dti-2185	67	17	and	and	CCONJ
dti-2185	67	18	isoflurane	isoflurane	NOUN
dti-2185	67	19	decreased	decrease	VERB
dti-2185	67	20	the	the	DET
dti-2185	67	21	relative	relative	ADJ
dti-2185	67	22	intensity	intensity	NOUN
dti-2185	67	23	of	of	ADP
dti-2185	67	24	lo	lo	PROPN
dti-2185	67	25	to	to	ADP
dti-2185	67	26	ld	ld	NOUN
dti-2185	67	27	phase	phase	NOUN
dti-2185	67	28	at	at	ADP
dti-2185	67	29	threeto	threeto	PROPN
dti-2185	68	1	fivefold	fivefold	PROPN
dti-2185	68	2	mac	mac	PROPN
dti-2185	68	3	.	.	PROPN
dti-2185	69	1	barbiturate	barbiturate	ADJ
dti-2185	69	2	pentobarbital	pentobarbital	NOUN
dti-2185	69	3	is	be	AUX
dti-2185	69	4	intravenously	intravenously	ADV
dti-2185	69	5	and	and	CCONJ
dti-2185	69	6	intraperitoneally	intraperitoneally	ADV
dti-2185	69	7	administered	administer	VERB
dti-2185	69	8	especially	especially	ADV
dti-2185	69	9	in	in	ADP
dti-2185	69	10	veterinary	veterinary	ADJ
dti-2185	69	11	anesthesia	anesthesia	NOUN
dti-2185	69	12	or	or	CCONJ
dti-2185	69	13	sedation	sedation	NOUN
dti-2185	69	14	.	.	PUNCT
dti-2185	70	1	sierra	sierra	PROPN
dti-2185	70	2	-	-	PUNCT
dti-2185	70	3	valdez	valdez	PROPN
dti-2185	70	4	et	et	NOUN
dti-2185	70	5	al	al	PROPN
dti-2185	70	6	characterized	characterize	VERB
dti-2185	70	7	the	the	PRON
dti-2185	70	8	in	in	ADP
dti-2185	70	9	vivo	vivo	ADJ
dti-2185	70	10	effects	effect	NOUN
dti-2185	70	11	of	of	ADP
dti-2185	70	12	pentobarbital	pentobarbital	NOUN
dti-2185	70	13	on	on	ADP
dti-2185	70	14	rat	rat	NOUN
dti-2185	70	15	brain	brain	NOUN
dti-2185	70	16	lipid	lipid	NOUN
dti-2185	70	17	rafts	raft	NOUN
dti-2185	70	18	,	,	PUNCT
dti-2185	70	19	which	which	PRON
dti-2185	70	20	were	be	AUX
dti-2185	70	21	isolated	isolate	VERB
dti-2185	70	22	15	15	NUM
dti-2185	70	23	min	min	NOUN
dti-2185	70	24	after	after	ADP
dti-2185	70	25	injecting	inject	VERB
dti-2185	70	26	rats	rat	NOUN
dti-2185	70	27	with	with	ADP
dti-2185	70	28	sodium	sodium	NOUN
dti-2185	70	29	pentobarbital	pentobarbital	NOUN
dti-2185	70	30	at	at	ADP
dti-2185	70	31	50	50	NUM
dti-2185	70	32	mg	mg	NUM
dti-2185	70	33	/	/	SYM
dti-2185	70	34	kg	kg	PROPN
dti-2185	70	35	intraperitoneally	intraperitoneally	ADV
dti-2185	70	36	(	(	PUNCT
dti-2185	70	37	38	38	NUM
dti-2185	70	38	)	)	PUNCT
dti-2185	70	39	.	.	PUNCT
dti-2185	71	1	dsc	dsc	NOUN
dti-2185	71	2	analysis	analysis	NOUN
dti-2185	71	3	revealed	reveal	VERB
dti-2185	71	4	that	that	SCONJ
dti-2185	71	5	pentobarbital	pentobarbital	NOUN
dti-2185	71	6	reduces	reduce	VERB
dti-2185	71	7	the	the	DET
dti-2185	71	8	transition	transition	NOUN
dti-2185	71	9	temperature	temperature	NOUN
dti-2185	71	10	from	from	ADP
dti-2185	71	11	lo	lo	PROPN
dti-2185	71	12	to	to	ADP
dti-2185	71	13	ld	ld	PROPN
dti-2185	71	14	phase	phase	NOUN
dti-2185	71	15	.	.	PUNCT
dti-2185	72	1	membranous	membranous	ADJ
dti-2185	72	2	sodium	sodium	NOUN
dti-2185	72	3	channel	channel	NOUN
dti-2185	72	4	blocker	blocker	NOUN
dti-2185	72	5	local	local	ADJ
dti-2185	72	6	anesthetics	anesthetic	NOUN
dti-2185	72	7	local	local	ADJ
dti-2185	72	8	anesthetics	anesthetic	NOUN
dti-2185	72	9	reversibly	reversibly	ADV
dti-2185	72	10	block	block	VERB
dti-2185	72	11	voltage	voltage	NOUN
dti-2185	72	12	-	-	PUNCT
dti-2185	72	13	gated	gate	VERB
dti-2185	72	14	sodium	sodium	NOUN
dti-2185	72	15	(	(	PUNCT
dti-2185	72	16	nav	nav	NOUN
dti-2185	72	17	)	)	PUNCT
dti-2185	72	18	channels	channel	NOUN
dti-2185	72	19	that	that	PRON
dti-2185	72	20	are	be	AUX
dti-2185	72	21	responsible	responsible	ADJ
dti-2185	72	22	for	for	ADP
dti-2185	72	23	the	the	DET
dti-2185	72	24	initiation	initiation	NOUN
dti-2185	72	25	and	and	CCONJ
dti-2185	72	26	propagation	propagation	NOUN
dti-2185	72	27	of	of	ADP
dti-2185	72	28	action	action	NOUN
dti-2185	72	29	potentials	potential	VERB
dti-2185	72	30	in	in	ADP
dti-2185	72	31	excitable	excitable	ADJ
dti-2185	72	32	cells	cell	NOUN
dti-2185	72	33	,	,	PUNCT
dti-2185	72	34	inhibiting	inhibit	VERB
dti-2185	72	35	sensory	sensory	ADJ
dti-2185	72	36	and	and	CCONJ
dti-2185	72	37	motor	motor	NOUN
dti-2185	72	38	functions	function	NOUN
dti-2185	72	39	(	(	PUNCT
dti-2185	72	40	39	39	NUM
dti-2185	72	41	)	)	PUNCT
dti-2185	72	42	.	.	PUNCT
dti-2185	73	1	among	among	ADP
dti-2185	73	2	nine	nine	NUM
dti-2185	73	3	distinct	distinct	ADJ
dti-2185	73	4	nav	nav	NOUN
dti-2185	73	5	channels	channel	NOUN
dti-2185	73	6	(	(	PUNCT
dti-2185	73	7	nav1.1	nav1.1	NOUN
dti-2185	73	8	to	to	ADP
dti-2185	73	9	nav1.9	nav1.9	ADV
dti-2185	73	10	)	)	PUNCT
dti-2185	73	11	cloned	clone	VERB
dti-2185	73	12	from	from	ADP
dti-2185	73	13	mammals	mammal	NOUN
dti-2185	73	14	,	,	PUNCT
dti-2185	73	15	nav1.8	nav1.8	PROPN
dti-2185	73	16	channel	channel	NOUN
dti-2185	73	17	plays	play	VERB
dti-2185	73	18	a	a	DET
dti-2185	73	19	crucial	crucial	ADJ
dti-2185	73	20	role	role	NOUN
dti-2185	73	21	in	in	ADP
dti-2185	73	22	pain	pain	NOUN
dti-2185	73	23	transmission	transmission	NOUN
dti-2185	73	24	and	and	CCONJ
dti-2185	73	25	this	this	DET
dti-2185	73	26	isoform	isoform	NOUN
dti-2185	73	27	is	be	AUX
dti-2185	73	28	implicated	implicate	VERB
dti-2185	73	29	as	as	ADP
dti-2185	73	30	a	a	DET
dti-2185	73	31	site	site	NOUN
dti-2185	73	32	of	of	ADP
dti-2185	73	33	action	action	NOUN
dti-2185	73	34	for	for	ADP
dti-2185	73	35	anesthetic	anesthetic	ADJ
dti-2185	73	36	and	and	CCONJ
dti-2185	73	37	analgesic	analgesic	ADJ
dti-2185	73	38	drugs	drug	NOUN
dti-2185	73	39	.	.	PUNCT
dti-2185	74	1	while	while	SCONJ
dti-2185	74	2	nav	nav	NOUN
dti-2185	74	3	channels	channel	NOUN
dti-2185	74	4	are	be	AUX
dti-2185	74	5	present	present	ADJ
dti-2185	74	6	in	in	ADP
dti-2185	74	7	caveolae	caveolae	NOUN
dti-2185	74	8	-	-	PUNCT
dti-2185	74	9	type	type	NOUN
dti-2185	74	10	and	and	CCONJ
dti-2185	74	11	non	non	ADJ
dti-2185	74	12	-	-	ADJ
dti-2185	74	13	caveolae	caveolae	ADJ
dti-2185	74	14	-	-	PUNCT
dti-2185	74	15	type	type	NOUN
dti-2185	74	16	lipid	lipid	NOUN
dti-2185	74	17	rafts	raft	NOUN
dti-2185	74	18	,	,	PUNCT
dti-2185	74	19	nav1.8	nav1.8	PROPN
dti-2185	74	20	channel	channel	NOUN
dti-2185	74	21	clustering	cluster	VERB
dti-2185	74	22	in	in	ADP
dti-2185	74	23	such	such	ADJ
dti-2185	74	24	membrane	membrane	NOUN
dti-2185	74	25	domains	domain	NOUN
dti-2185	74	26	is	be	AUX
dti-2185	74	27	essential	essential	ADJ
dti-2185	74	28	to	to	ADP
dti-2185	74	29	the	the	DET
dti-2185	74	30	propagation	propagation	NOUN
dti-2185	74	31	of	of	ADP
dti-2185	74	32	action	action	NOUN
dti-2185	74	33	potentials	potential	VERB
dti-2185	74	34	in	in	ADP
dti-2185	74	35	nociceptive	nociceptive	ADJ
dti-2185	74	36	axons	axon	NOUN
dti-2185	74	37	(	(	PUNCT
dti-2185	74	38	40,41	40,41	NOUN
dti-2185	74	39	)	)	PUNCT
dti-2185	74	40	.	.	PUNCT
dti-2185	75	1	nav1.8	nav1.8	NUM
dti-2185	75	2	channels	channel	NOUN
dti-2185	75	3	are	be	AUX
dti-2185	75	4	associated	associate	VERB
dti-2185	75	5	with	with	ADP
dti-2185	75	6	lipid	lipid	ADJ
dti-2185	75	7	rafts	raft	NOUN
dti-2185	75	8	in	in	ADP
dti-2185	75	9	rat	rat	NOUN
dti-2185	75	10	dorsal	dorsal	NOUN
dti-2185	75	11	root	root	NOUN
dti-2185	75	12	ganglionic	ganglionic	ADJ
dti-2185	75	13	neurons	neuron	NOUN
dti-2185	75	14	,	,	PUNCT
dti-2185	75	15	but	but	CCONJ
dti-2185	75	16	cholesterol	cholesterol	NOUN
dti-2185	75	17	depletion	depletion	NOUN
dti-2185	75	18	induces	induce	VERB
dti-2185	75	19	dissociation	dissociation	NOUN
dti-2185	75	20	between	between	ADP
dti-2185	75	21	nav1.8	nav1.8	PROPN
dti-2185	75	22	channels	channel	NOUN
dti-2185	75	23	and	and	CCONJ
dti-2185	75	24	lipid	lipid	NOUN
dti-2185	75	25	rafts	raft	NOUN
dti-2185	75	26	(	(	PUNCT
dti-2185	75	27	42	42	NUM
dti-2185	75	28	)	)	PUNCT
dti-2185	75	29	.	.	PUNCT
dti-2185	76	1	results	result	NOUN
dti-2185	76	2	of	of	ADP
dti-2185	76	3	the	the	DET
dti-2185	76	4	literature	literature	NOUN
dti-2185	76	5	search	search	NOUN
dti-2185	76	6	on	on	ADP
dti-2185	76	7	the	the	DET
dti-2185	76	8	interaction	interaction	NOUN
dti-2185	76	9	of	of	ADP
dti-2185	76	10	local	local	ADJ
dti-2185	76	11	anesthetics	anesthetic	NOUN
dti-2185	76	12	with	with	ADP
dti-2185	76	13	membrane	membrane	NOUN
dti-2185	76	14	lipid	lipid	NOUN
dti-2185	76	15	rafts	raft	NOUN
dti-2185	76	16	and	and	CCONJ
dti-2185	76	17	membranes	membrane	NOUN
dti-2185	76	18	are	be	AUX
dti-2185	76	19	shown	show	VERB
dti-2185	76	20	in	in	ADP
dti-2185	76	21	table	table	NOUN
dti-2185	76	22	ii	ii	PROPN
dti-2185	76	23	.	.	PUNCT
dti-2185	77	1	kamata	kamata	PROPN
dti-2185	77	2	et	et	PROPN
dti-2185	77	3	al	al	PROPN
dti-2185	77	4	incubated	incubate	VERB
dti-2185	77	5	human	human	ADJ
dti-2185	77	6	erythrocytes	erythrocyte	NOUN
dti-2185	77	7	with	with	ADP
dti-2185	77	8	lidocaine	lidocaine	NOUN
dti-2185	77	9	at	at	ADP
dti-2185	77	10	18.4	18.4	NUM
dti-2185	77	11	mm	mm	NOUN
dti-2185	77	12	and	and	CCONJ
dti-2185	77	13	prepared	prepare	VERB
dti-2185	77	14	erythrocyte	erythrocyte	NOUN
dti-2185	77	15	ghosts	ghost	NOUN
dti-2185	77	16	,	,	PUNCT
dti-2185	77	17	followed	follow	VERB
dti-2185	77	18	by	by	ADP
dti-2185	77	19	sdgc	sdgc	NOUN
dti-2185	77	20	fractionation	fractionation	NOUN
dti-2185	77	21	and	and	CCONJ
dti-2185	77	22	immunoblotting	immunoblotte	VERB
dti-2185	77	23	analysis	analysis	NOUN
dti-2185	77	24	for	for	ADP
dti-2185	77	25	flotillin-1	flotillin-1	NUM
dti-2185	77	26	(	(	PUNCT
dti-2185	77	27	caveolae	caveolae	NOUN
dti-2185	77	28	-	-	PUNCT
dti-2185	77	29	associated	associate	VERB
dti-2185	77	30	integral	integral	ADJ
dti-2185	77	31	membrane	membrane	NOUN
dti-2185	77	32	protein	protein	NOUN
dti-2185	77	33	)	)	PUNCT
dti-2185	77	34	that	that	PRON
dti-2185	77	35	is	be	AUX
dti-2185	77	36	assumed	assume	VERB
dti-2185	77	37	to	to	PART
dti-2185	77	38	stabilize	stabilize	VERB
dti-2185	77	39	lipid	lipid	NOUN
dti-2185	77	40	rafts	raft	NOUN
dti-2185	77	41	(	(	PUNCT
dti-2185	77	42	43	43	NUM
dti-2185	77	43	)	)	PUNCT
dti-2185	77	44	.	.	PUNCT
dti-2185	78	1	lidocaine	lidocaine	PROPN
dti-2185	78	2	reversibly	reversibly	ADV
dti-2185	78	3	disrupted	disrupt	VERB
dti-2185	78	4	erythrocyte	erythrocyte	ADJ
dti-2185	78	5	membrane	membrane	NOUN
dti-2185	78	6	lipid	lipid	NOUN
dti-2185	78	7	rafts	raft	NOUN
dti-2185	78	8	and	and	CCONJ
dti-2185	78	9	abolished	abolish	VERB
dti-2185	78	10	flotillin-1	flotillin-1	PUNCT
dti-2185	78	11	in	in	ADP
dti-2185	78	12	lipid	lipid	ADJ
dti-2185	78	13	rafts	raft	NOUN
dti-2185	78	14	together	together	ADV
dti-2185	78	15	with	with	ADP
dti-2185	78	16	depleting	deplete	VERB
dti-2185	78	17	cholesterol	cholesterol	NOUN
dti-2185	78	18	.	.	PUNCT
dti-2185	79	1	bandeiras	bandeira	NOUN
dti-2185	79	2	et	et	PROPN
dti-2185	79	3	al	al	PROPN
dti-2185	79	4	treated	treat	VERB
dti-2185	79	5	luvs	luvs	PROPN
dti-2185	79	6	prepared	prepare	VERB
dti-2185	79	7	with	with	ADP
dti-2185	79	8	popc	popc	NOUN
dti-2185	79	9	,	,	PUNCT
dti-2185	79	10	sm	sm	PROPN
dti-2185	79	11	and	and	CCONJ
dti-2185	79	12	cholesterol	cholesterol	NOUN
dti-2185	79	13	(	(	PUNCT
dti-2185	79	14	1:1:1	1:1:1	PROPN
dti-2185	79	15	molar	molar	ADJ
dti-2185	79	16	ratio	ratio	NOUN
dti-2185	79	17	)	)	PUNCT
dti-2185	79	18	with	with	ADP
dti-2185	79	19	tetracaine	tetracaine	NOUN
dti-2185	79	20	and	and	CCONJ
dti-2185	79	21	lidocaine	lidocaine	NOUN
dti-2185	79	22	,	,	PUNCT
dti-2185	79	23	and	and	CCONJ
dti-2185	79	24	then	then	ADV
dti-2185	79	25	evaluated	evaluate	VERB
dti-2185	79	26	their	their	PRON
dti-2185	79	27	membrane	membrane	NOUN
dti-2185	79	28	effects	effect	NOUN
dti-2185	79	29	by	by	ADP
dti-2185	79	30	dsc	dsc	NOUN
dti-2185	79	31	and	and	CCONJ
dti-2185	79	32	phosphorus	phosphorus	NOUN
dti-2185	79	33	nmr	nmr	NOUN
dti-2185	79	34	spectroscopy	spectroscopy	NOUN
dti-2185	79	35	(	(	PUNCT
dti-2185	79	36	44	44	NUM
dti-2185	79	37	)	)	PUNCT
dti-2185	79	38	.	.	PUNCT
dti-2185	80	1	tetracaine	tetracaine	NOUN
dti-2185	80	2	and	and	CCONJ
dti-2185	80	3	lidocaine	lidocaine	NOUN
dti-2185	80	4	increased	increase	VERB
dti-2185	80	5	the	the	DET
dti-2185	80	6	fluidity	fluidity	NOUN
dti-2185	80	7	of	of	ADP
dti-2185	80	8	raft	raft	NOUN
dti-2185	80	9	-	-	PUNCT
dti-2185	80	10	like	like	ADJ
dti-2185	80	11	membranes	membrane	NOUN
dti-2185	80	12	at	at	ADP
dti-2185	80	13	25	25	NUM
dti-2185	80	14	and	and	CCONJ
dti-2185	80	15	69	69	NUM
dti-2185	80	16	mm	mm	NUM
dti-2185	80	17	,	,	PUNCT
dti-2185	80	18	table	table	NOUN
dti-2185	80	19	ii	ii	NOUN
dti-2185	80	20	interaction	interaction	NOUN
dti-2185	80	21	of	of	ADP
dti-2185	80	22	membranous	membranous	ADJ
dti-2185	80	23	sodium	sodium	NOUN
dti-2185	80	24	channel	channel	NOUN
dti-2185	80	25	blocker	blocker	NOUN
dti-2185	80	26	local	local	ADJ
dti-2185	80	27	anesthetics	anesthetic	NOUN
dti-2185	80	28	with	with	ADP
dti-2185	80	29	lipid	lipid	NOUN
dti-2185	80	30	raft	raft	NOUN
dti-2185	80	31	membrane	membrane	NOUN
dti-2185	80	32	domains	domain	NOUN
dti-2185	80	33	and	and	CCONJ
dti-2185	80	34	membranes	membrane	NOUN
dti-2185	80	35	drug	drug	NOUN
dti-2185	80	36	class	class	NOUN
dti-2185	80	37	drug	drug	NOUN
dti-2185	80	38	membrane	membrane	NOUN
dti-2185	80	39	induced	induce	VERB
dti-2185	80	40	membrane	membrane	NOUN
dti-2185	80	41	modification	modification	NOUN
dti-2185	80	42	reference	reference	NOUN
dti-2185	80	43	local	local	ADJ
dti-2185	80	44	anesthetic	anesthetic	ADJ
dti-2185	80	45	lidocaine	lidocaine	NOUN
dti-2185	80	46	(	(	PUNCT
dti-2185	80	47	18.4	18.4	NUM
dti-2185	80	48	mm	mm	NOUN
dti-2185	80	49	)	)	PUNCT
dti-2185	80	50	human	human	ADJ
dti-2185	80	51	erythrocyte	erythrocyte	NOUN
dti-2185	80	52	membranes	membrane	NOUN
dti-2185	80	53	disrupted	disrupt	VERB
dti-2185	80	54	membrane	membrane	NOUN
dti-2185	80	55	rafts	raft	NOUN
dti-2185	80	56	reversely	reversely	ADV
dti-2185	80	57	and	and	CCONJ
dti-2185	80	58	abolished	abolish	VERB
dti-2185	80	59	flotillin-1	flotillin-1	PUNCT
dti-2185	80	60	in	in	ADP
dti-2185	80	61	lipid	lipid	ADJ
dti-2185	80	62	rafts	raft	NOUN
dti-2185	80	63	43	43	NUM
dti-2185	80	64	local	local	ADJ
dti-2185	80	65	anesthetic	anesthetic	NOUN
dti-2185	80	66	tetracaine	tetracaine	NOUN
dti-2185	80	67	(	(	PUNCT
dti-2185	80	68	25	25	NUM
dti-2185	80	69	mm	mm	NOUN
dti-2185	80	70	)	)	PUNCT
dti-2185	80	71	lidocaine	lidocaine	NOUN
dti-2185	80	72	(	(	PUNCT
dti-2185	80	73	69	69	NUM
dti-2185	80	74	mm	mm	NOUN
dti-2185	80	75	)	)	PUNCT
dti-2185	80	76	luvs	luvs	NOUN
dti-2185	80	77	(	(	PUNCT
dti-2185	80	78	popc	popc	PROPN
dti-2185	80	79	,	,	PUNCT
dti-2185	80	80	sm	sm	PROPN
dti-2185	80	81	and	and	CCONJ
dti-2185	80	82	cholesterol	cholesterol	PROPN
dti-2185	80	83	,	,	PUNCT
dti-2185	80	84	1:1:1	1:1:1	PROPN
dti-2185	80	85	molar	molar	ADJ
dti-2185	80	86	ratio	ratio	NOUN
dti-2185	80	87	)	)	PUNCT
dti-2185	80	88	increased	increase	VERB
dti-2185	80	89	the	the	DET
dti-2185	80	90	fluidity	fluidity	NOUN
dti-2185	80	91	of	of	ADP
dti-2185	80	92	raft	raft	NOUN
dti-2185	80	93	-	-	PUNCT
dti-2185	80	94	like	like	ADJ
dti-2185	80	95	membranes	membrane	NOUN
dti-2185	80	96	44	44	NUM
dti-2185	80	97	local	local	ADJ
dti-2185	80	98	anesthetic	anesthetic	NOUN
dti-2185	80	99	dibucaine	dibucaine	NOUN
dti-2185	80	100	(	(	PUNCT
dti-2185	80	101	0.05	0.05	NUM
dti-2185	80	102	and	and	CCONJ
dti-2185	80	103	0.2	0.2	NUM
dti-2185	80	104	mm	mm	NOUN
dti-2185	80	105	)	)	PUNCT
dti-2185	80	106	raft	raft	NOUN
dti-2185	80	107	-	-	PUNCT
dti-2185	80	108	like	like	ADJ
dti-2185	80	109	membranes	membrane	NOUN
dti-2185	80	110	(	(	PUNCT
dti-2185	80	111	popc	popc	NOUN
dti-2185	80	112	,	,	PUNCT
dti-2185	80	113	dppc	dppc	NOUN
dti-2185	80	114	and	and	CCONJ
dti-2185	80	115	cholesterol	cholesterol	NOUN
dti-2185	80	116	,	,	PUNCT
dti-2185	80	117	2:1:1	2:1:1	NUM
dti-2185	80	118	molar	molar	NOUN
dti-2185	80	119	ratio	ratio	NOUN
dti-2185	80	120	)	)	PUNCT
dti-2185	80	121	reduced	reduce	VERB
dti-2185	80	122	the	the	DET
dti-2185	80	123	miscibility	miscibility	NOUN
dti-2185	80	124	temperature	temperature	NOUN
dti-2185	80	125	of	of	ADP
dti-2185	80	126	lo	lo	PROPN
dti-2185	80	127	and	and	CCONJ
dti-2185	80	128	ld	ld	NOUN
dti-2185	80	129	phase	phase	NOUN
dti-2185	80	130	separation	separation	NOUN
dti-2185	80	131	45	45	NUM
dti-2185	80	132	local	local	ADJ
dti-2185	80	133	anesthetic	anesthetic	NOUN
dti-2185	80	134	lidocaine	lidocaine	NOUN
dti-2185	80	135	(	(	PUNCT
dti-2185	80	136	10	10	NUM
dti-2185	80	137	-	-	SYM
dti-2185	80	138	20	20	NUM
dti-2185	80	139	mol%	mol%	NOUN
dti-2185	80	140	)	)	PUNCT
dti-2185	80	141	tetracaine	tetracaine	NOUN
dti-2185	80	142	(	(	PUNCT
dti-2185	80	143	10	10	NUM
dti-2185	80	144	-	-	SYM
dti-2185	80	145	20	20	NUM
dti-2185	80	146	mol%	mol%	NOUN
dti-2185	80	147	)	)	PUNCT
dti-2185	80	148	raft	raft	NOUN
dti-2185	80	149	-	-	PUNCT
dti-2185	80	150	like	like	ADJ
dti-2185	80	151	membranes	membrane	NOUN
dti-2185	80	152	(	(	PUNCT
dti-2185	80	153	popc	popc	NOUN
dti-2185	80	154	,	,	PUNCT
dti-2185	80	155	dppc	dppc	NOUN
dti-2185	80	156	and	and	CCONJ
dti-2185	80	157	cholesterol	cholesterol	NOUN
dti-2185	80	158	,	,	PUNCT
dti-2185	80	159	2:2:1	2:2:1	NUM
dti-2185	80	160	molar	molar	ADJ
dti-2185	80	161	ratio	ratio	NOUN
dti-2185	80	162	)	)	PUNCT
dti-2185	80	163	reduced	reduce	VERB
dti-2185	80	164	the	the	DET
dti-2185	80	165	miscibility	miscibility	NOUN
dti-2185	80	166	temperature	temperature	NOUN
dti-2185	80	167	of	of	ADP
dti-2185	80	168	lo	lo	PROPN
dti-2185	80	169	and	and	CCONJ
dti-2185	80	170	ld	ld	NOUN
dti-2185	80	171	phase	phase	NOUN
dti-2185	80	172	separation	separation	NOUN
dti-2185	80	173	and	and	CCONJ
dti-2185	80	174	decreased	decrease	VERB
dti-2185	80	175	the	the	DET
dti-2185	80	176	line	line	NOUN
dti-2185	80	177	tension	tension	NOUN
dti-2185	80	178	at	at	ADP
dti-2185	80	179	lo	lo	PROPN
dti-2185	80	180	/	/	SYM
dti-2185	80	181	ld	ld	PROPN
dti-2185	80	182	phase	phase	NOUN
dti-2185	80	183	boundary	boundary	ADJ
dti-2185	80	184	46	46	NUM
dti-2185	80	185	local	local	ADJ
dti-2185	80	186	anesthetic	anesthetic	NOUN
dti-2185	80	187	dibucaine	dibucaine	NOUN
dti-2185	80	188	(	(	PUNCT
dti-2185	80	189	0.2	0.2	NUM
dti-2185	80	190	mm	mm	NOUN
dti-2185	80	191	)	)	PUNCT
dti-2185	80	192	tetracaine	tetracaine	NOUN
dti-2185	80	193	(	(	PUNCT
dti-2185	80	194	0.2	0.2	NUM
dti-2185	80	195	mm	mm	NOUN
dti-2185	80	196	)	)	PUNCT
dti-2185	80	197	luvs	luvs	NOUN
dti-2185	80	198	(	(	PUNCT
dti-2185	80	199	popc	popc	PROPN
dti-2185	80	200	,	,	PUNCT
dti-2185	80	201	sm	sm	PROPN
dti-2185	80	202	and	and	CCONJ
dti-2185	80	203	cholesterol	cholesterol	NOUN
dti-2185	80	204	,	,	PUNCT
dti-2185	80	205	16:43:41	16:43:41	NUM
dti-2185	80	206	molar	molar	ADJ
dti-2185	80	207	ratio	ratio	NOUN
dti-2185	80	208	)	)	PUNCT
dti-2185	80	209	increased	increase	VERB
dti-2185	80	210	the	the	DET
dti-2185	80	211	fluidity	fluidity	NOUN
dti-2185	80	212	of	of	ADP
dti-2185	80	213	lo	lo	PROPN
dti-2185	80	214	phase	phase	NOUN
dti-2185	80	215	membranes	membrane	NOUN
dti-2185	80	216	,	,	PUNCT
dti-2185	80	217	but	but	CCONJ
dti-2185	80	218	not	not	PART
dti-2185	80	219	ld	ld	NOUN
dti-2185	80	220	phase	phase	NOUN
dti-2185	80	221	membranes	membrane	NOUN
dti-2185	80	222	47	47	NUM
dti-2185	80	223	local	local	ADJ
dti-2185	80	224	anesthetic	anesthetic	NOUN
dti-2185	80	225	lidocaine	lidocaine	NOUN
dti-2185	80	226	(	(	PUNCT
dti-2185	80	227	50	50	NUM
dti-2185	80	228	-	-	SYM
dti-2185	80	229	200	200	NUM
dti-2185	80	230	μm	μm	NUM
dti-2185	80	231	)	)	PUNCT
dti-2185	80	232	bupivacaine	bupivacaine	NOUN
dti-2185	80	233	(	(	PUNCT
dti-2185	80	234	50	50	NUM
dti-2185	80	235	-	-	SYM
dti-2185	80	236	200	200	NUM
dti-2185	80	237	μm	μm	NUM
dti-2185	80	238	)	)	PUNCT
dti-2185	80	239	ropivacaine	ropivacaine	NOUN
dti-2185	80	240	(	(	PUNCT
dti-2185	80	241	50	50	NUM
dti-2185	80	242	-	-	SYM
dti-2185	80	243	200	200	NUM
dti-2185	80	244	μm	μm	NUM
dti-2185	80	245	)	)	PUNCT
dti-2185	80	246	prilocaine	prilocaine	NOUN
dti-2185	80	247	(	(	PUNCT
dti-2185	80	248	50	50	NUM
dti-2185	80	249	-	-	SYM
dti-2185	80	250	200	200	NUM
dti-2185	80	251	μm	μm	NUM
dti-2185	80	252	)	)	PUNCT
dti-2185	80	253	suvs	suvs	NOUN
dti-2185	80	254	(	(	PUNCT
dti-2185	80	255	dopc	dopc	NOUN
dti-2185	80	256	,	,	PUNCT
dti-2185	80	257	pope	pope	NOUN
dti-2185	80	258	,	,	PUNCT
dti-2185	80	259	sm	sm	PROPN
dti-2185	80	260	,	,	PUNCT
dti-2185	80	261	cb	cb	PROPN
dti-2185	80	262	and	and	CCONJ
dti-2185	80	263	cholesterol	cholesterol	PROPN
dti-2185	80	264	,	,	PUNCT
dti-2185	80	265	16.7:16.7:16.7:16.7:33.3	16.7:16.7:16.7:16.7:33.3	NUM
dti-2185	80	266	;	;	PUNCT
dti-2185	80	267	dopc	dopc	NOUN
dti-2185	80	268	,	,	PUNCT
dti-2185	80	269	sm	sm	PROPN
dti-2185	80	270	and	and	CCONJ
dti-2185	80	271	cholesterol	cholesterol	PROPN
dti-2185	80	272	,	,	PUNCT
dti-2185	80	273	33.3:33.3:33.3	33.3:33.3:33.3	NUM
dti-2185	80	274	;	;	PUNCT
dti-2185	80	275	and	and	CCONJ
dti-2185	80	276	dopc	dopc	NOUN
dti-2185	80	277	,	,	PUNCT
dti-2185	80	278	pope	pope	NOUN
dti-2185	80	279	,	,	PUNCT
dti-2185	80	280	pops	pop	NOUN
dti-2185	80	281	,	,	PUNCT
dti-2185	80	282	sm	sm	NOUN
dti-2185	80	283	and	and	CCONJ
dti-2185	80	284	cholesterol	cholesterol	NOUN
dti-2185	80	285	,	,	PUNCT
dti-2185	80	286	5:5:10:40:40	5:5:10:40:40	NUM
dti-2185	80	287	molar	molar	ADJ
dti-2185	80	288	ratio	ratio	NOUN
dti-2185	80	289	)	)	PUNCT
dti-2185	80	290	increased	increase	VERB
dti-2185	80	291	the	the	DET
dti-2185	80	292	membrane	membrane	NOUN
dti-2185	80	293	fluidity	fluidity	NOUN
dti-2185	80	294	with	with	ADP
dti-2185	80	295	the	the	DET
dti-2185	80	296	relative	relative	ADJ
dti-2185	80	297	potency	potency	NOUN
dti-2185	80	298	being	be	AUX
dti-2185	80	299	bupivacaine	bupivacaine	NOUN
dti-2185	80	300	>	>	X
dti-2185	80	301	ropivacaine	ropivacaine	PROPN
dti-2185	80	302	>	>	X
dti-2185	80	303	lidocaine	lidocaine	NOUN
dti-2185	80	304	>	>	X
dti-2185	80	305	prilocaine	prilocaine	NOUN
dti-2185	80	306	more	more	ADV
dti-2185	80	307	effective	effective	ADJ
dti-2185	80	308	in	in	ADP
dti-2185	80	309	interacting	interact	VERB
dti-2185	80	310	with	with	ADP
dti-2185	80	311	the	the	DET
dti-2185	80	312	reference	reference	NOUN
dti-2185	80	313	biomimetic	biomimetic	ADJ
dti-2185	80	314	membranes	membrane	NOUN
dti-2185	80	315	than	than	ADP
dti-2185	80	316	the	the	DET
dti-2185	80	317	raft	raft	NOUN
dti-2185	80	318	model	model	NOUN
dti-2185	80	319	membranes	membrane	NOUN
dti-2185	80	320	49	49	NUM
dti-2185	80	321	local	local	ADJ
dti-2185	80	322	anesthetic	anesthetic	ADJ
dti-2185	80	323	bupivacaine	bupivacaine	NOUN
dti-2185	80	324	enantiomers	enantiomer	NOUN
dti-2185	80	325	(	(	PUNCT
dti-2185	80	326	5	5	NUM
dti-2185	80	327	-	-	SYM
dti-2185	80	328	50	50	NUM
dti-2185	80	329	μm	μm	NUM
dti-2185	80	330	)	)	PUNCT
dti-2185	80	331	suvs	suvs	NOUN
dti-2185	80	332	(	(	PUNCT
dti-2185	80	333	popc	popc	NOUN
dti-2185	80	334	,	,	PUNCT
dti-2185	80	335	pope	pope	NOUN
dti-2185	80	336	,	,	PUNCT
dti-2185	80	337	pops	pop	NOUN
dti-2185	80	338	,	,	PUNCT
dti-2185	80	339	popi	popi	PROPN
dti-2185	80	340	,	,	PUNCT
dti-2185	80	341	sm	sm	PROPN
dti-2185	80	342	,	,	PUNCT
dti-2185	80	343	cardiolipin	cardiolipin	NOUN
dti-2185	80	344	and	and	CCONJ
dti-2185	80	345	cholesterol	cholesterol	NOUN
dti-2185	80	346	,	,	PUNCT
dti-2185	80	347	25:16:3:3:3:10:40	25:16:3:3:3:10:40	PROPN
dti-2185	80	348	molar	molar	ADJ
dti-2185	80	349	ratio	ratio	NOUN
dti-2185	80	350	)	)	PUNCT
dti-2185	80	351	increased	increase	VERB
dti-2185	80	352	the	the	DET
dti-2185	80	353	fluidity	fluidity	NOUN
dti-2185	80	354	of	of	ADP
dti-2185	80	355	biomimetic	biomimetic	ADJ
dti-2185	80	356	membranes	membrane	NOUN
dti-2185	80	357	with	with	ADP
dti-2185	80	358	the	the	DET
dti-2185	80	359	relative	relative	ADJ
dti-2185	80	360	potency	potency	NOUN
dti-2185	80	361	being	be	AUX
dti-2185	80	362	r(+)-bupivacaine	r(+)-bupivacaine	NOUN
dti-2185	80	363	>	>	X
dti-2185	80	364	racemic	racemic	ADJ
dti-2185	80	365	bupivacaine	bupivacaine	NOUN
dti-2185	80	366	>	>	X
dti-2185	80	367	s(–)-bupivacaine	s(–)-bupivacaine	PROPN
dti-2185	80	368	50	50	NUM
dti-2185	80	369	cb	cb	NOUN
dti-2185	80	370	=	=	SYM
dti-2185	80	371	cerebroside	cerebroside	NOUN
dti-2185	80	372	;	;	PUNCT
dti-2185	81	1	dopc	dopc	NOUN
dti-2185	81	2	=	=	SYM
dti-2185	81	3	1,2	1,2	NUM
dti-2185	81	4	-	-	PUNCT
dti-2185	81	5	dioleoylphosphatidylcholine	dioleoylphosphatidylcholine	NOUN
dti-2185	81	6	;	;	PUNCT
dti-2185	81	7	dppc	dppc	NOUN
dti-2185	81	8	=	=	SYM
dti-2185	81	9	1,2	1,2	NUM
dti-2185	81	10	-	-	NUM
dti-2185	81	11	dipalmitoylphosphatidylcholine	dipalmitoylphosphatidylcholine	NOUN
dti-2185	81	12	;	;	PUNCT
dti-2185	81	13	luv	luv	NOUN
dti-2185	81	14	=	=	PROPN
dti-2185	81	15	large	large	ADJ
dti-2185	81	16	unilamellar	unilamellar	ADJ
dti-2185	81	17	vesicle	vesicle	NOUN
dti-2185	81	18	;	;	PUNCT
dti-2185	81	19	popc	popc	NOUN
dti-2185	81	20	=	=	SYM
dti-2185	81	21	1	1	NUM
dti-2185	81	22	-	-	PUNCT
dti-2185	81	23	palmitoyl2	palmitoyl2	NOUN
dti-2185	81	24	-	-	PUNCT
dti-2185	81	25	oleoylphosphatidylcholine	oleoylphosphatidylcholine	NOUN
dti-2185	81	26	;	;	PUNCT
dti-2185	81	27	pope	pope	NOUN
dti-2185	81	28	=	=	SYM
dti-2185	81	29	1	1	NUM
dti-2185	81	30	-	-	PUNCT
dti-2185	81	31	palmitoyl-2	palmitoyl-2	VERB
dti-2185	81	32	-	-	PUNCT
dti-2185	81	33	oleoylphosphatidylethanolamine	oleoylphosphatidylethanolamine	NOUN
dti-2185	81	34	;	;	PUNCT
dti-2185	81	35	popi	popi	PROPN
dti-2185	81	36	=	=	SYM
dti-2185	81	37	1	1	NUM
dti-2185	81	38	-	-	PUNCT
dti-2185	81	39	palmitoyl-2	palmitoyl-2	VERB
dti-2185	81	40	-	-	PUNCT
dti-2185	81	41	oleoylphosphatidylinositol	oleoylphosphatidylinositol	NOUN
dti-2185	81	42	;	;	PUNCT
dti-2185	81	43	pops	pop	NOUN
dti-2185	81	44	=	=	SYM
dti-2185	81	45	1	1	NUM
dti-2185	81	46	-	-	PUNCT
dti-2185	81	47	palmitoyl2	palmitoyl2	NOUN
dti-2185	81	48	-	-	PUNCT
dti-2185	81	49	oleoylphosphatidylserine	oleoylphosphatidylserine	ADJ
dti-2185	81	50	;	;	PUNCT
dti-2185	81	51	sm	sm	PROPN
dti-2185	81	52	=	=	SYM
dti-2185	81	53	sphingomyelin	sphingomyelin	NOUN
dti-2185	81	54	;	;	PUNCT
dti-2185	81	55	suv	suv	X
dti-2185	81	56	=	=	SYM
dti-2185	81	57	small	small	ADJ
dti-2185	81	58	unilamellar	unilamellar	ADJ
dti-2185	81	59	vesicle	vesicle	NOUN
dti-2185	81	60	.	.	PUNCT
dti-2185	82	1	interaction	interaction	NOUN
dti-2185	82	2	of	of	ADP
dti-2185	82	3	drugs	drug	NOUN
dti-2185	82	4	with	with	ADP
dti-2185	82	5	lipid	lipid	NOUN
dti-2185	82	6	rafts38	rafts38	NOUN
dti-2185	83	1	©	©	PROPN
dti-2185	83	2	2020	2020	NUM
dti-2185	84	1	the	the	DET
dti-2185	84	2	authors	author	NOUN
dti-2185	84	3	.	.	PUNCT
dti-2185	84	4	published	publish	VERB
dti-2185	84	5	by	by	ADP
dti-2185	84	6	aboutscience	aboutscience	NOUN
dti-2185	84	7	respectively	respectively	ADV
dti-2185	84	8	.	.	PUNCT
dti-2185	85	1	yoshida	yoshida	PROPN
dti-2185	85	2	et	et	PROPN
dti-2185	85	3	al	al	PROPN
dti-2185	85	4	prepared	prepare	VERB
dti-2185	85	5	lipid	lipid	NOUN
dti-2185	85	6	bilayer	bilayer	NOUN
dti-2185	85	7	membranes	membrane	NOUN
dti-2185	85	8	with	with	ADP
dti-2185	85	9	dopc	dopc	NOUN
dti-2185	85	10	,	,	PUNCT
dti-2185	85	11	dppc	dppc	NOUN
dti-2185	85	12	and	and	CCONJ
dti-2185	85	13	cholesterol	cholesterol	NOUN
dti-2185	85	14	(	(	PUNCT
dti-2185	85	15	2:1:1	2:1:1	NUM
dti-2185	85	16	molar	molar	ADJ
dti-2185	85	17	ratio	ratio	NOUN
dti-2185	85	18	)	)	PUNCT
dti-2185	85	19	to	to	PART
dti-2185	85	20	be	be	AUX
dti-2185	85	21	laterally	laterally	ADV
dti-2185	85	22	separated	separate	VERB
dti-2185	85	23	into	into	ADP
dti-2185	85	24	lo	lo	PROPN
dti-2185	85	25	and	and	CCONJ
dti-2185	85	26	ld	ld	PROPN
dti-2185	85	27	phase	phase	NOUN
dti-2185	85	28	together	together	ADV
dti-2185	85	29	with	with	ADP
dti-2185	85	30	labeling	label	VERB
dti-2185	85	31	the	the	DET
dti-2185	85	32	membranes	membrane	NOUN
dti-2185	85	33	with	with	ADP
dti-2185	85	34	fluorescent	fluorescent	ADJ
dti-2185	85	35	probe	probe	NOUN
dti-2185	85	36	rhodamine	rhodamine	PROPN
dti-2185	85	37	dhpe	dhpe	PROPN
dti-2185	85	38	(	(	PUNCT
dti-2185	85	39	dihexadecanoyl	dihexadecanoyl	NOUN
dti-2185	85	40	-	-	PUNCT
dti-2185	85	41	sn	sn	NOUN
dti-2185	85	42	-	-	PUNCT
dti-2185	85	43	glycero-3	glycero-3	NOUN
dti-2185	85	44	-	-	PUNCT
dti-2185	85	45	phosphoethanolamine	phosphoethanolamine	NOUN
dti-2185	85	46	)	)	PUNCT
dti-2185	85	47	(	(	PUNCT
dti-2185	85	48	45	45	NUM
dti-2185	85	49	)	)	PUNCT
dti-2185	85	50	.	.	PUNCT
dti-2185	86	1	after	after	ADP
dti-2185	86	2	treating	treat	VERB
dti-2185	86	3	the	the	DET
dti-2185	86	4	membrane	membrane	NOUN
dti-2185	86	5	preparations	preparation	NOUN
dti-2185	86	6	with	with	ADP
dti-2185	86	7	dibucaine	dibucaine	NOUN
dti-2185	86	8	at	at	ADP
dti-2185	86	9	0.05	0.05	NUM
dti-2185	86	10	and	and	CCONJ
dti-2185	86	11	0.2	0.2	NUM
dti-2185	86	12	mm	mm	NOUN
dti-2185	86	13	,	,	PUNCT
dti-2185	86	14	they	they	PRON
dti-2185	86	15	observed	observe	VERB
dti-2185	86	16	the	the	DET
dti-2185	86	17	raft	raft	NOUN
dti-2185	86	18	-	-	PUNCT
dti-2185	86	19	like	like	ADJ
dti-2185	86	20	membrane	membrane	NOUN
dti-2185	86	21	domains	domain	NOUN
dti-2185	86	22	by	by	ADP
dti-2185	86	23	fluorescence	fluorescence	NOUN
dti-2185	86	24	microscopy	microscopy	NOUN
dti-2185	86	25	at	at	ADP
dti-2185	86	26	20	20	NUM
dti-2185	86	27	-	-	SYM
dti-2185	86	28	40	40	NUM
dti-2185	86	29	°	°	NOUN
dti-2185	86	30	c	c	NOUN
dti-2185	86	31	to	to	PART
dti-2185	86	32	determine	determine	VERB
dti-2185	86	33	changes	change	NOUN
dti-2185	86	34	in	in	ADP
dti-2185	86	35	miscibility	miscibility	NOUN
dti-2185	86	36	temperature	temperature	NOUN
dti-2185	86	37	of	of	ADP
dti-2185	86	38	the	the	DET
dti-2185	86	39	lo	lo	PROPN
dti-2185	86	40	and	and	CCONJ
dti-2185	86	41	ld	ld	NOUN
dti-2185	86	42	phase	phase	NOUN
dti-2185	86	43	separation	separation	NOUN
dti-2185	86	44	and	and	CCONJ
dti-2185	86	45	in	in	ADP
dti-2185	86	46	line	line	NOUN
dti-2185	86	47	tension	tension	NOUN
dti-2185	86	48	at	at	ADP
dti-2185	86	49	the	the	DET
dti-2185	86	50	lo	lo	PROPN
dti-2185	86	51	/	/	SYM
dti-2185	86	52	ld	ld	PROPN
dti-2185	86	53	phase	phase	NOUN
dti-2185	86	54	boundary	boundary	NOUN
dti-2185	86	55	.	.	PUNCT
dti-2185	87	1	dibucaine	dibucaine	PROPN
dti-2185	87	2	reduced	reduce	VERB
dti-2185	87	3	the	the	DET
dti-2185	87	4	miscibility	miscibility	NOUN
dti-2185	87	5	temperature	temperature	NOUN
dti-2185	87	6	,	,	PUNCT
dti-2185	87	7	which	which	PRON
dti-2185	87	8	was	be	AUX
dti-2185	87	9	accompanied	accompany	VERB
dti-2185	87	10	by	by	ADP
dti-2185	87	11	the	the	DET
dti-2185	87	12	line	line	NOUN
dti-2185	87	13	tension	tension	NOUN
dti-2185	87	14	decrease	decrease	NOUN
dti-2185	87	15	.	.	PUNCT
dti-2185	88	1	dibucaine	dibucaine	PROPN
dti-2185	88	2	also	also	ADV
dti-2185	88	3	made	make	VERB
dti-2185	88	4	the	the	DET
dti-2185	88	5	lo	lo	PROPN
dti-2185	88	6	domains	domain	NOUN
dti-2185	88	7	smaller	small	ADJ
dti-2185	88	8	at	at	ADP
dti-2185	88	9	25	25	NUM
dti-2185	88	10	°	°	NOUN
dti-2185	88	11	c	c	NOUN
dti-2185	88	12	,	,	PUNCT
dti-2185	88	13	although	although	SCONJ
dti-2185	88	14	most	most	ADJ
dti-2185	88	15	membranes	membrane	NOUN
dti-2185	88	16	were	be	AUX
dti-2185	88	17	present	present	ADJ
dti-2185	88	18	without	without	ADP
dti-2185	88	19	such	such	ADJ
dti-2185	88	20	raft	raft	NOUN
dti-2185	88	21	-	-	PUNCT
dti-2185	88	22	like	like	ADJ
dti-2185	88	23	domains	domain	NOUN
dti-2185	88	24	at	at	ADP
dti-2185	88	25	above	above	ADP
dti-2185	88	26	25	25	NUM
dti-2185	88	27	°	°	NOUN
dti-2185	88	28	c	c	NOUN
dti-2185	88	29	.	.	PUNCT
dti-2185	89	1	in	in	ADP
dti-2185	89	2	a	a	DET
dti-2185	89	3	similar	similar	ADJ
dti-2185	89	4	microscopic	microscopic	ADJ
dti-2185	89	5	experiment	experiment	NOUN
dti-2185	89	6	using	use	VERB
dti-2185	89	7	liposomes	liposome	NOUN
dti-2185	89	8	prepared	prepare	VERB
dti-2185	89	9	with	with	ADP
dti-2185	89	10	dopc	dopc	NOUN
dti-2185	89	11	,	,	PUNCT
dti-2185	89	12	dppc	dppc	NOUN
dti-2185	89	13	and	and	CCONJ
dti-2185	89	14	cholesterol	cholesterol	NOUN
dti-2185	89	15	(	(	PUNCT
dti-2185	89	16	2:2:1	2:2:1	NUM
dti-2185	89	17	molar	molar	ADJ
dti-2185	89	18	ratio	ratio	NOUN
dti-2185	89	19	)	)	PUNCT
dti-2185	89	20	,	,	PUNCT
dti-2185	89	21	lidocaine	lidocaine	NOUN
dti-2185	89	22	and	and	CCONJ
dti-2185	89	23	tetracaine	tetracaine	NOUN
dti-2185	89	24	reduced	reduce	VERB
dti-2185	89	25	the	the	DET
dti-2185	89	26	miscibility	miscibility	NOUN
dti-2185	89	27	temperature	temperature	NOUN
dti-2185	89	28	of	of	ADP
dti-2185	89	29	ternary	ternary	ADJ
dti-2185	89	30	membranes	membrane	NOUN
dti-2185	89	31	at	at	ADP
dti-2185	89	32	10	10	NUM
dti-2185	89	33	-	-	SYM
dti-2185	89	34	20	20	NUM
dti-2185	89	35	mol%	mol%	PROPN
dti-2185	89	36	relative	relative	ADJ
dti-2185	89	37	to	to	ADP
dti-2185	89	38	liposomal	liposomal	PROPN
dti-2185	89	39	lipids	lipids	PROPN
dti-2185	89	40	,	,	PUNCT
dti-2185	89	41	but	but	CCONJ
dti-2185	89	42	not	not	PART
dti-2185	89	43	binary	binary	ADJ
dti-2185	89	44	membranes	membrane	NOUN
dti-2185	89	45	without	without	ADP
dti-2185	89	46	cholesterol	cholesterol	NOUN
dti-2185	89	47	(	(	PUNCT
dti-2185	89	48	46	46	NUM
dti-2185	89	49	)	)	PUNCT
dti-2185	89	50	.	.	PUNCT
dti-2185	90	1	both	both	DET
dti-2185	90	2	local	local	ADJ
dti-2185	90	3	anesthetics	anesthetic	NOUN
dti-2185	90	4	also	also	ADV
dti-2185	90	5	decreased	decrease	VERB
dti-2185	90	6	the	the	DET
dti-2185	90	7	line	line	NOUN
dti-2185	90	8	tension	tension	NOUN
dti-2185	90	9	at	at	ADP
dti-2185	90	10	the	the	DET
dti-2185	90	11	lo	lo	PROPN
dti-2185	90	12	/	/	SYM
dti-2185	90	13	ld	ld	PROPN
dti-2185	90	14	phase	phase	NOUN
dti-2185	90	15	boundary	boundary	NOUN
dti-2185	90	16	.	.	PUNCT
dti-2185	91	1	kinoshita	kinoshita	PROPN
dti-2185	91	2	et	et	PROPN
dti-2185	91	3	al	al	PROPN
dti-2185	91	4	performed	perform	VERB
dti-2185	91	5	fa	fa	NOUN
dti-2185	91	6	experiments	experiment	NOUN
dti-2185	91	7	to	to	PART
dti-2185	91	8	reveal	reveal	VERB
dti-2185	91	9	the	the	DET
dti-2185	91	10	effects	effect	NOUN
dti-2185	91	11	of	of	ADP
dti-2185	91	12	local	local	ADJ
dti-2185	91	13	anesthetics	anesthetic	NOUN
dti-2185	91	14	on	on	ADP
dti-2185	91	15	raft	raft	NOUN
dti-2185	91	16	-	-	PUNCT
dti-2185	91	17	like	like	ADJ
dti-2185	91	18	lo	lo	PROPN
dti-2185	91	19	/	/	SYM
dti-2185	91	20	non	non	ADJ
dti-2185	91	21	-	-	ADJ
dti-2185	91	22	raft	raft	ADJ
dti-2185	91	23	ld	ld	NOUN
dti-2185	91	24	phase	phase	NOUN
dti-2185	91	25	membranes	membrane	NOUN
dti-2185	91	26	by	by	ADP
dti-2185	91	27	using	use	VERB
dti-2185	91	28	luvs	luvs	PROPN
dti-2185	91	29	that	that	PRON
dti-2185	91	30	were	be	AUX
dti-2185	91	31	prepared	prepare	VERB
dti-2185	91	32	with	with	ADP
dti-2185	91	33	dopc	dopc	NOUN
dti-2185	91	34	,	,	PUNCT
dti-2185	91	35	sm	sm	PROPN
dti-2185	91	36	and	and	CCONJ
dti-2185	91	37	cholesterol	cholesterol	NOUN
dti-2185	91	38	(	(	PUNCT
dti-2185	91	39	16:43:41	16:43:41	NUM
dti-2185	91	40	and	and	CCONJ
dti-2185	91	41	65:16:19	65:16:19	NUM
dti-2185	91	42	in	in	ADP
dti-2185	91	43	molar	molar	ADJ
dti-2185	91	44	ratio	ratio	NOUN
dti-2185	91	45	for	for	ADP
dti-2185	91	46	lo	lo	PROPN
dti-2185	91	47	phase	phase	NOUN
dti-2185	91	48	and	and	CCONJ
dti-2185	91	49	ld	ld	NOUN
dti-2185	91	50	phase	phase	NOUN
dti-2185	91	51	,	,	PUNCT
dti-2185	91	52	respectively	respectively	ADV
dti-2185	91	53	)	)	PUNCT
dti-2185	91	54	(	(	PUNCT
dti-2185	91	55	47	47	NUM
dti-2185	91	56	)	)	PUNCT
dti-2185	91	57	.	.	PUNCT
dti-2185	92	1	dibucaine	dibucaine	PROPN
dti-2185	92	2	disordered	disorder	VERB
dti-2185	92	3	the	the	DET
dti-2185	92	4	lipid	lipid	NOUN
dti-2185	92	5	packing	packing	NOUN
dti-2185	92	6	or	or	CCONJ
dti-2185	92	7	increased	increase	VERB
dti-2185	92	8	the	the	DET
dti-2185	92	9	fluidity	fluidity	NOUN
dti-2185	92	10	of	of	ADP
dti-2185	92	11	lo	lo	PROPN
dti-2185	92	12	phase	phase	NOUN
dti-2185	92	13	membranes	membrane	NOUN
dti-2185	92	14	at	at	ADP
dti-2185	92	15	0.2	0.2	NUM
dti-2185	92	16	mm	mm	NOUN
dti-2185	92	17	more	more	ADV
dti-2185	92	18	potently	potently	ADV
dti-2185	92	19	than	than	ADP
dti-2185	92	20	tetracaine	tetracaine	NOUN
dti-2185	92	21	,	,	PUNCT
dti-2185	92	22	whereas	whereas	SCONJ
dti-2185	92	23	dibucaine	dibucaine	NOUN
dti-2185	92	24	and	and	CCONJ
dti-2185	92	25	tetracaine	tetracaine	NOUN
dti-2185	92	26	showed	show	VERB
dti-2185	92	27	no	no	DET
dti-2185	92	28	significant	significant	ADJ
dti-2185	92	29	effects	effect	NOUN
dti-2185	92	30	on	on	ADP
dti-2185	92	31	ld	ld	NOUN
dti-2185	92	32	phase	phase	NOUN
dti-2185	92	33	membranes	membrane	NOUN
dti-2185	92	34	.	.	PUNCT
dti-2185	93	1	however	however	ADV
dti-2185	93	2	,	,	PUNCT
dti-2185	93	3	these	these	DET
dti-2185	93	4	studies	study	NOUN
dti-2185	93	5	(	(	PUNCT
dti-2185	93	6	43	43	NUM
dti-2185	93	7	-	-	SYM
dti-2185	93	8	47	47	NUM
dti-2185	93	9	)	)	PUNCT
dti-2185	93	10	used	use	VERB
dti-2185	93	11	drug	drug	NOUN
dti-2185	93	12	concentrations	concentration	NOUN
dti-2185	93	13	much	much	ADV
dti-2185	93	14	higher	high	ADJ
dti-2185	93	15	than	than	ADP
dti-2185	93	16	clinically	clinically	ADV
dti-2185	93	17	and	and	CCONJ
dti-2185	93	18	experimentally	experimentally	ADV
dti-2185	93	19	relevant	relevant	ADJ
dti-2185	93	20	ones	one	NOUN
dti-2185	93	21	(	(	PUNCT
dti-2185	93	22	48	48	NUM
dti-2185	93	23	)	)	PUNCT
dti-2185	93	24	and	and	CCONJ
dti-2185	93	25	the	the	DET
dti-2185	93	26	tested	test	VERB
dti-2185	93	27	dibucaine	dibucaine	NOUN
dti-2185	93	28	and	and	CCONJ
dti-2185	93	29	tetracaine	tetracaine	NOUN
dti-2185	93	30	are	be	AUX
dti-2185	93	31	not	not	PART
dti-2185	93	32	widely	widely	ADV
dti-2185	93	33	used	use	VERB
dti-2185	93	34	in	in	ADP
dti-2185	93	35	clinical	clinical	ADJ
dti-2185	93	36	anesthesia	anesthesia	NOUN
dti-2185	93	37	.	.	PUNCT
dti-2185	94	1	tsuchiya	tsuchiya	PROPN
dti-2185	94	2	et	et	PROPN
dti-2185	94	3	al	al	PROPN
dti-2185	94	4	prepared	prepare	VERB
dti-2185	94	5	small	small	ADJ
dti-2185	94	6	unilamellar	unilamellar	ADJ
dti-2185	94	7	vesicles	vesicle	NOUN
dti-2185	94	8	(	(	PUNCT
dti-2185	94	9	suvs	suvs	NOUN
dti-2185	94	10	)	)	PUNCT
dti-2185	94	11	with	with	ADP
dti-2185	94	12	dopc	dopc	NOUN
dti-2185	94	13	,	,	PUNCT
dti-2185	94	14	pope	pope	NOUN
dti-2185	94	15	,	,	PUNCT
dti-2185	94	16	sm	sm	PROPN
dti-2185	94	17	,	,	PUNCT
dti-2185	94	18	cerebroside	cerebroside	NOUN
dti-2185	94	19	(	(	PUNCT
dti-2185	94	20	cb	cb	PROPN
dti-2185	94	21	)	)	PUNCT
dti-2185	94	22	and	and	CCONJ
dti-2185	94	23	cholesterol	cholesterol	NOUN
dti-2185	94	24	(	(	PUNCT
dti-2185	94	25	16.7:16.7:16.7:16.7:33.3	16.7:16.7:16.7:16.7:33.3	NUM
dti-2185	94	26	molar	molar	ADJ
dti-2185	94	27	ratio	ratio	NOUN
dti-2185	94	28	)	)	PUNCT
dti-2185	94	29	;	;	PUNCT
dti-2185	94	30	dopc	dopc	NOUN
dti-2185	94	31	,	,	PUNCT
dti-2185	94	32	sm	sm	PROPN
dti-2185	94	33	and	and	CCONJ
dti-2185	94	34	cholesterol	cholesterol	NOUN
dti-2185	94	35	(	(	PUNCT
dti-2185	94	36	33.3:33.3:33.3	33.3:33.3:33.3	NUM
dti-2185	94	37	molar	molar	ADJ
dti-2185	94	38	ratio	ratio	NOUN
dti-2185	94	39	)	)	PUNCT
dti-2185	94	40	;	;	PUNCT
dti-2185	94	41	and	and	CCONJ
dti-2185	94	42	dopc	dopc	NOUN
dti-2185	94	43	,	,	PUNCT
dti-2185	94	44	pope	pope	NOUN
dti-2185	94	45	,	,	PUNCT
dti-2185	94	46	pops	pop	NOUN
dti-2185	94	47	,	,	PUNCT
dti-2185	94	48	sm	sm	PROPN
dti-2185	94	49	and	and	CCONJ
dti-2185	94	50	cholesterol	cholesterol	NOUN
dti-2185	94	51	(	(	PUNCT
dti-2185	94	52	5:5:10:40:40	5:5:10:40:40	NUM
dti-2185	94	53	molar	molar	ADJ
dti-2185	94	54	ratio	ratio	NOUN
dti-2185	94	55	)	)	PUNCT
dti-2185	94	56	for	for	ADP
dti-2185	94	57	raft	raft	NOUN
dti-2185	94	58	model	model	NOUN
dti-2185	94	59	membranes	membrane	NOUN
dti-2185	94	60	,	,	PUNCT
dti-2185	94	61	and	and	CCONJ
dti-2185	94	62	popc	popc	NOUN
dti-2185	94	63	,	,	PUNCT
dti-2185	94	64	pope	pope	NOUN
dti-2185	94	65	,	,	PUNCT
dti-2185	94	66	pops	pop	NOUN
dti-2185	94	67	,	,	PUNCT
dti-2185	94	68	1	1	NUM
dti-2185	94	69	-	-	PUNCT
dti-2185	94	70	palmitoyl2	palmitoyl2	NOUN
dti-2185	94	71	-	-	PUNCT
dti-2185	94	72	oleoylphosphatidylinositol	oleoylphosphatidylinositol	NOUN
dti-2185	94	73	(	(	PUNCT
dti-2185	94	74	popi	popi	PROPN
dti-2185	94	75	)	)	PUNCT
dti-2185	94	76	,	,	PUNCT
dti-2185	94	77	sm	sm	PROPN
dti-2185	94	78	,	,	PUNCT
dti-2185	94	79	cardiolipin	cardiolipin	NOUN
dti-2185	94	80	and	and	CCONJ
dti-2185	94	81	cholesterol	cholesterol	NOUN
dti-2185	94	82	(	(	PUNCT
dti-2185	94	83	25:16:3:3:3:10:40	25:16:3:3:3:10:40	PROPN
dti-2185	94	84	molar	molar	ADJ
dti-2185	94	85	ratio	ratio	NOUN
dti-2185	94	86	)	)	PUNCT
dti-2185	94	87	for	for	ADP
dti-2185	94	88	reference	reference	NOUN
dti-2185	94	89	biomimetic	biomimetic	ADJ
dti-2185	94	90	membranes	membrane	NOUN
dti-2185	94	91	(	(	PUNCT
dti-2185	94	92	49,50	49,50	NOUN
dti-2185	94	93	)	)	PUNCT
dti-2185	94	94	.	.	PUNCT
dti-2185	95	1	they	they	PRON
dti-2185	95	2	treated	treat	VERB
dti-2185	95	3	these	these	DET
dti-2185	95	4	membrane	membrane	ADJ
dti-2185	95	5	preparations	preparation	NOUN
dti-2185	95	6	with	with	ADP
dti-2185	95	7	lidocaine	lidocaine	NOUN
dti-2185	95	8	,	,	PUNCT
dti-2185	95	9	bupivacaine	bupivacaine	NOUN
dti-2185	95	10	,	,	PUNCT
dti-2185	95	11	ropivacaine	ropivacaine	NOUN
dti-2185	95	12	and	and	CCONJ
dti-2185	95	13	prilocaine	prilocaine	NOUN
dti-2185	95	14	at	at	ADP
dti-2185	95	15	anesthetic	anesthetic	NOUN
dti-2185	95	16	and	and	CCONJ
dti-2185	95	17	cardiotoxic	cardiotoxic	ADJ
dti-2185	95	18	concentrations	concentration	NOUN
dti-2185	95	19	,	,	PUNCT
dti-2185	95	20	followed	follow	VERB
dti-2185	95	21	by	by	ADP
dti-2185	95	22	fp	fp	NOUN
dti-2185	95	23	measurements	measurement	NOUN
dti-2185	95	24	.	.	PUNCT
dti-2185	96	1	all	all	DET
dti-2185	96	2	the	the	DET
dti-2185	96	3	tested	test	VERB
dti-2185	96	4	anesthetics	anesthetic	NOUN
dti-2185	96	5	interacted	interact	VERB
dti-2185	96	6	with	with	ADP
dti-2185	96	7	raft	raft	NOUN
dti-2185	96	8	model	model	NOUN
dti-2185	96	9	and	and	CCONJ
dti-2185	96	10	biomimetic	biomimetic	ADJ
dti-2185	96	11	membranes	membrane	NOUN
dti-2185	96	12	to	to	PART
dti-2185	96	13	increase	increase	VERB
dti-2185	96	14	the	the	DET
dti-2185	96	15	membrane	membrane	NOUN
dti-2185	96	16	fluidity	fluidity	NOUN
dti-2185	96	17	at	at	ADP
dti-2185	96	18	50	50	NUM
dti-2185	96	19	-	-	SYM
dti-2185	96	20	200	200	NUM
dti-2185	96	21	μm	μm	NOUN
dti-2185	96	22	with	with	ADP
dti-2185	96	23	the	the	DET
dti-2185	96	24	relative	relative	ADJ
dti-2185	96	25	potency	potency	NOUN
dti-2185	96	26	being	be	AUX
dti-2185	96	27	bupivacaine	bupivacaine	NOUN
dti-2185	96	28	>	>	X
dti-2185	96	29	ropivacaine	ropivacaine	PROPN
dti-2185	96	30	>	>	X
dti-2185	96	31	lidocaine	lidocaine	NOUN
dti-2185	96	32	>	>	X
dti-2185	96	33	prilocaine	prilocaine	NOUN
dti-2185	96	34	(	(	PUNCT
dti-2185	96	35	49	49	NUM
dti-2185	96	36	)	)	PUNCT
dti-2185	96	37	.	.	PUNCT
dti-2185	97	1	they	they	PRON
dti-2185	97	2	were	be	AUX
dti-2185	97	3	more	more	ADV
dti-2185	97	4	effective	effective	ADJ
dti-2185	97	5	in	in	ADP
dti-2185	97	6	interacting	interact	VERB
dti-2185	97	7	with	with	ADP
dti-2185	97	8	the	the	DET
dti-2185	97	9	reference	reference	NOUN
dti-2185	97	10	membranes	membrane	NOUN
dti-2185	97	11	than	than	ADP
dti-2185	97	12	the	the	DET
dti-2185	97	13	raft	raft	NOUN
dti-2185	97	14	membranes	membrane	NOUN
dti-2185	97	15	.	.	PUNCT
dti-2185	98	1	biomimetic	biomimetic	ADJ
dti-2185	98	2	membranes	membrane	NOUN
dti-2185	98	3	showed	show	VERB
dti-2185	98	4	different	different	ADJ
dti-2185	98	5	interactivity	interactivity	NOUN
dti-2185	98	6	with	with	ADP
dti-2185	98	7	the	the	DET
dti-2185	98	8	relative	relative	ADJ
dti-2185	98	9	potency	potency	NOUN
dti-2185	98	10	being	be	AUX
dti-2185	98	11	r(+)-bupivacaine	r(+)-bupivacaine	NOUN
dti-2185	98	12	>	>	X
dti-2185	98	13	racemic	racemic	ADJ
dti-2185	98	14	bupivacaine	bupivacaine	NOUN
dti-2185	98	15	>	>	X
dti-2185	98	16	s(–)-bupivacaine	s(–)-bupivacaine	PROPN
dti-2185	98	17	at	at	ADP
dti-2185	98	18	5	5	NUM
dti-2185	98	19	-	-	SYM
dti-2185	98	20	50	50	NUM
dti-2185	98	21	μm	μm	NOUN
dti-2185	98	22	,	,	PUNCT
dti-2185	98	23	being	be	AUX
dti-2185	98	24	consistent	consistent	ADJ
dti-2185	98	25	with	with	ADP
dti-2185	98	26	the	the	DET
dti-2185	98	27	rank	rank	NOUN
dti-2185	98	28	order	order	NOUN
dti-2185	98	29	of	of	ADP
dti-2185	98	30	their	their	PRON
dti-2185	98	31	anesthetic	anesthetic	NOUN
dti-2185	98	32	and	and	CCONJ
dti-2185	98	33	cardiotoxic	cardiotoxic	ADJ
dti-2185	98	34	effects	effect	NOUN
dti-2185	98	35	(	(	PUNCT
dti-2185	98	36	50	50	NUM
dti-2185	98	37	)	)	PUNCT
dti-2185	98	38	.	.	PUNCT
dti-2185	99	1	however	however	ADV
dti-2185	99	2	,	,	PUNCT
dti-2185	99	3	raft	raft	NOUN
dti-2185	99	4	model	model	NOUN
dti-2185	99	5	membranes	membrane	NOUN
dti-2185	99	6	did	do	AUX
dti-2185	99	7	not	not	PART
dti-2185	99	8	exhibit	exhibit	VERB
dti-2185	99	9	significant	significant	ADJ
dti-2185	99	10	enantioselectivity	enantioselectivity	NOUN
dti-2185	99	11	as	as	ADP
dti-2185	99	12	the	the	DET
dti-2185	99	13	reference	reference	NOUN
dti-2185	99	14	biomimetic	biomimetic	ADJ
dti-2185	99	15	membranes	membrane	NOUN
dti-2185	99	16	.	.	PUNCT
dti-2185	100	1	these	these	DET
dti-2185	100	2	results	result	NOUN
dti-2185	100	3	may	may	AUX
dti-2185	100	4	suggest	suggest	VERB
dti-2185	100	5	that	that	SCONJ
dti-2185	100	6	lipid	lipid	NOUN
dti-2185	100	7	rafts	raft	NOUN
dti-2185	100	8	are	be	AUX
dti-2185	100	9	less	less	ADV
dti-2185	100	10	likely	likely	ADJ
dti-2185	100	11	to	to	PART
dti-2185	100	12	contribute	contribute	VERB
dti-2185	100	13	at	at	ADP
dti-2185	100	14	least	least	ADJ
dti-2185	100	15	to	to	ADP
dti-2185	100	16	the	the	DET
dti-2185	100	17	enantioselective	enantioselective	ADJ
dti-2185	100	18	effects	effect	NOUN
dti-2185	100	19	of	of	ADP
dti-2185	100	20	local	local	ADJ
dti-2185	100	21	anesthetics	anesthetic	NOUN
dti-2185	100	22	.	.	PUNCT
dti-2185	101	1	membranous	membranous	ADJ
dti-2185	101	2	receptorand	receptorand	NOUN
dti-2185	101	3	enzyme	enzyme	NOUN
dti-2185	101	4	-	-	PUNCT
dti-2185	101	5	acting	act	VERB
dti-2185	101	6	drugs	drug	NOUN
dti-2185	101	7	results	result	NOUN
dti-2185	101	8	of	of	ADP
dti-2185	101	9	the	the	DET
dti-2185	101	10	literature	literature	NOUN
dti-2185	101	11	search	search	NOUN
dti-2185	101	12	on	on	ADP
dti-2185	101	13	the	the	DET
dti-2185	101	14	interaction	interaction	NOUN
dti-2185	101	15	of	of	ADP
dti-2185	101	16	receptor	receptor	NOUN
dti-2185	101	17	-	-	PUNCT
dti-2185	101	18	acting	act	VERB
dti-2185	101	19	adrenergic	adrenergic	NOUN
dti-2185	101	20	and	and	CCONJ
dti-2185	101	21	opioid	opioid	ADJ
dti-2185	101	22	drugs	drug	NOUN
dti-2185	101	23	and	and	CCONJ
dti-2185	101	24	enzyme	enzyme	NOUN
dti-2185	101	25	acting	act	VERB
dti-2185	101	26	anti	anti	ADJ
dti-2185	101	27	-	-	ADJ
dti-2185	101	28	inflammatory	inflammatory	ADJ
dti-2185	101	29	drugs	drug	NOUN
dti-2185	101	30	with	with	ADP
dti-2185	101	31	membrane	membrane	NOUN
dti-2185	101	32	lipid	lipid	NOUN
dti-2185	101	33	rafts	raft	NOUN
dti-2185	101	34	and	and	CCONJ
dti-2185	101	35	membranes	membrane	NOUN
dti-2185	101	36	are	be	AUX
dti-2185	101	37	shown	show	VERB
dti-2185	101	38	in	in	ADP
dti-2185	101	39	table	table	NOUN
dti-2185	101	40	iii	iii	PROPN
dti-2185	101	41	.	.	PUNCT
dti-2185	101	42	beta	beta	NOUN
dti-2185	101	43	-	-	PUNCT
dti-2185	101	44	adrenergic	adrenergic	ADJ
dti-2185	101	45	blockers	blocker	NOUN
dti-2185	101	46	beta	beta	NOUN
dti-2185	101	47	-	-	PUNCT
dti-2185	101	48	blockers	blocker	NOUN
dti-2185	101	49	are	be	AUX
dti-2185	101	50	perioperatively	perioperatively	ADV
dti-2185	101	51	used	use	VERB
dti-2185	101	52	to	to	PART
dti-2185	101	53	reduce	reduce	VERB
dti-2185	101	54	the	the	DET
dti-2185	101	55	risk	risk	NOUN
dti-2185	101	56	of	of	ADP
dti-2185	101	57	myocardial	myocardial	ADJ
dti-2185	101	58	ischemia	ischemia	NOUN
dti-2185	101	59	,	,	PUNCT
dti-2185	101	60	arrhythmia	arrhythmia	NOUN
dti-2185	101	61	and	and	CCONJ
dti-2185	101	62	cardiac	cardiac	ADJ
dti-2185	101	63	morbidity	morbidity	NOUN
dti-2185	101	64	during	during	ADP
dti-2185	101	65	anesthesia	anesthesia	PROPN
dti-2185	101	66	.	.	PUNCT
dti-2185	102	1	lipid	lipid	NOUN
dti-2185	102	2	raft	raft	PROPN
dti-2185	102	3	/	/	SYM
dti-2185	102	4	caveola	caveola	NOUN
dti-2185	102	5	domains	domain	NOUN
dti-2185	102	6	encompass	encompass	VERB
dti-2185	102	7	β2adrenergic	β2adrenergic	ADJ
dti-2185	102	8	receptors	receptor	NOUN
dti-2185	102	9	,	,	PUNCT
dti-2185	102	10	but	but	CCONJ
dti-2185	102	11	not	not	PART
dti-2185	102	12	β1	β1	VERB
dti-2185	102	13	-	-	PUNCT
dti-2185	102	14	adrenergic	adrenergic	NOUN
dti-2185	102	15	receptors	receptor	NOUN
dti-2185	102	16	for	for	ADP
dti-2185	102	17	signal	signal	ADJ
dti-2185	102	18	transduction	transduction	NOUN
dti-2185	102	19	(	(	PUNCT
dti-2185	102	20	12,51	12,51	NUM
dti-2185	102	21	)	)	PUNCT
dti-2185	102	22	.	.	PUNCT
dti-2185	103	1	mizogami	mizogami	PROPN
dti-2185	103	2	et	et	PROPN
dti-2185	103	3	al	al	PROPN
dti-2185	103	4	prepared	prepare	VERB
dti-2185	103	5	suvs	suvs	NOUN
dti-2185	103	6	with	with	ADP
dti-2185	103	7	popc	popc	NOUN
dti-2185	103	8	,	,	PUNCT
dti-2185	103	9	sm	sm	PROPN
dti-2185	103	10	,	,	PUNCT
dti-2185	103	11	pope	pope	PROPN
dti-2185	103	12	,	,	PUNCT
dti-2185	103	13	cb	cb	PROPN
dti-2185	103	14	and	and	CCONJ
dti-2185	103	15	cholesterol	cholesterol	NOUN
dti-2185	103	16	(	(	PUNCT
dti-2185	103	17	1:1:1:1:2	1:1:1:1:2	NUM
dti-2185	103	18	molar	molar	ADJ
dti-2185	103	19	ratio	ratio	NOUN
dti-2185	103	20	)	)	PUNCT
dti-2185	103	21	to	to	PART
dti-2185	103	22	compare	compare	VERB
dti-2185	103	23	the	the	DET
dti-2185	103	24	membrane	membrane	NOUN
dti-2185	103	25	effects	effect	NOUN
dti-2185	103	26	between	between	ADP
dti-2185	103	27	different	different	ADJ
dti-2185	103	28	β	β	NOUN
dti-2185	103	29	-	-	NOUN
dti-2185	103	30	blockers	blocker	NOUN
dti-2185	103	31	at	at	ADP
dti-2185	103	32	0.2	0.2	NUM
dti-2185	103	33	and	and	CCONJ
dti-2185	103	34	1	1	NUM
dti-2185	103	35	mm	mm	NOUN
dti-2185	103	36	by	by	ADP
dti-2185	103	37	measuring	measure	VERB
dti-2185	103	38	fp	fp	PROPN
dti-2185	103	39	(	(	PUNCT
dti-2185	103	40	52	52	NUM
dti-2185	103	41	)	)	PUNCT
dti-2185	103	42	.	.	PUNCT
dti-2185	104	1	nonselective	nonselective	ADJ
dti-2185	104	2	propranolol	propranolol	NOUN
dti-2185	104	3	most	most	ADV
dti-2185	104	4	potently	potently	ADV
dti-2185	104	5	increased	increase	VERB
dti-2185	104	6	the	the	DET
dti-2185	104	7	fluidity	fluidity	NOUN
dti-2185	104	8	of	of	ADP
dti-2185	104	9	raft	raft	NOUN
dti-2185	104	10	model	model	NOUN
dti-2185	104	11	membranes	membrane	NOUN
dti-2185	104	12	,	,	PUNCT
dti-2185	104	13	followed	follow	VERB
dti-2185	104	14	by	by	ADP
dti-2185	104	15	alprenolol	alprenolol	NOUN
dti-2185	104	16	and	and	CCONJ
dti-2185	104	17	oxprenolol	oxprenolol	NOUN
dti-2185	104	18	,	,	PUNCT
dti-2185	104	19	but	but	CCONJ
dti-2185	104	20	not	not	PART
dti-2185	104	21	β1	β1	VERB
dti-2185	104	22	-	-	PUNCT
dti-2185	104	23	selective	selective	ADJ
dti-2185	104	24	atenolol	atenolol	PROPN
dti-2185	104	25	,	,	PUNCT
dti-2185	104	26	metoprolol	metoprolol	PROPN
dti-2185	104	27	and	and	CCONJ
dti-2185	104	28	esmolol	esmolol	PROPN
dti-2185	104	29	.	.	PUNCT
dti-2185	105	1	in	in	ADP
dti-2185	105	2	a	a	DET
dti-2185	105	3	similar	similar	ADJ
dti-2185	105	4	fp	fp	ADJ
dti-2185	105	5	study	study	NOUN
dti-2185	105	6	using	use	VERB
dti-2185	105	7	suvs	suvs	NOUN
dti-2185	105	8	prepared	prepare	VERB
dti-2185	105	9	with	with	ADP
dti-2185	105	10	33.3	33.3	NUM
dti-2185	105	11	mol%	mol%	PROPN
dti-2185	105	12	cholesterol	cholesterol	NOUN
dti-2185	105	13	and	and	CCONJ
dti-2185	105	14	66.7	66.7	NUM
dti-2185	105	15	mol%	mol%	PROPN
dti-2185	105	16	phospholipids	phospholipid	NOUN
dti-2185	105	17	consisting	consist	VERB
dti-2185	105	18	of	of	ADP
dti-2185	105	19	equimolar	equimolar	NOUN
dti-2185	105	20	dopc	dopc	NOUN
dti-2185	105	21	,	,	PUNCT
dti-2185	105	22	sm	sm	INTJ
dti-2185	105	23	,	,	PUNCT
dti-2185	105	24	pope	pope	NOUN
dti-2185	105	25	and	and	CCONJ
dti-2185	105	26	cb	cb	PROPN
dti-2185	105	27	,	,	PUNCT
dti-2185	105	28	nonselective	nonselective	ADJ
dti-2185	105	29	propranolol	propranolol	NOUN
dti-2185	105	30	and	and	CCONJ
dti-2185	105	31	alprenolol	alprenolol	NOUN
dti-2185	105	32	increased	increase	VERB
dti-2185	105	33	the	the	DET
dti-2185	105	34	fluidity	fluidity	NOUN
dti-2185	105	35	of	of	ADP
dti-2185	105	36	raft	raft	NOUN
dti-2185	105	37	model	model	NOUN
dti-2185	105	38	membranes	membrane	NOUN
dti-2185	105	39	at	at	ADP
dti-2185	105	40	20	20	NUM
dti-2185	105	41	-	-	SYM
dti-2185	105	42	200	200	NUM
dti-2185	105	43	μm	μm	NOUN
dti-2185	105	44	,	,	PUNCT
dti-2185	105	45	whereas	whereas	SCONJ
dti-2185	105	46	β1	β1	NOUN
dti-2185	105	47	-	-	PUNCT
dti-2185	105	48	selective	selective	ADJ
dti-2185	105	49	landiolol	landiolol	NOUN
dti-2185	105	50	and	and	CCONJ
dti-2185	105	51	esmolol	esmolol	PROPN
dti-2185	105	52	were	be	AUX
dti-2185	105	53	not	not	PART
dti-2185	105	54	effective	effective	ADJ
dti-2185	105	55	even	even	ADV
dti-2185	105	56	at	at	ADP
dti-2185	105	57	200	200	NUM
dti-2185	105	58	μm	μm	NOUN
dti-2185	105	59	(	(	PUNCT
dti-2185	105	60	53	53	NUM
dti-2185	105	61	)	)	PUNCT
dti-2185	105	62	.	.	PUNCT
dti-2185	106	1	nonselective	nonselective	ADJ
dti-2185	106	2	β	β	NOUN
dti-2185	106	3	-	-	NOUN
dti-2185	106	4	blockers	blocker	NOUN
dti-2185	106	5	could	could	AUX
dti-2185	106	6	reduce	reduce	VERB
dti-2185	106	7	the	the	DET
dti-2185	106	8	activity	activity	NOUN
dti-2185	106	9	of	of	ADP
dti-2185	106	10	β2	β2	NOUN
dti-2185	106	11	-	-	PUNCT
dti-2185	106	12	adrenergic	adrenergic	NOUN
dti-2185	106	13	receptors	receptor	NOUN
dti-2185	106	14	by	by	ADP
dti-2185	106	15	fluidizing	fluidize	VERB
dti-2185	106	16	the	the	DET
dti-2185	106	17	membrane	membrane	NOUN
dti-2185	106	18	lipid	lipid	NOUN
dti-2185	106	19	rafts	raft	NOUN
dti-2185	106	20	together	together	ADV
dti-2185	106	21	with	with	ADP
dti-2185	106	22	antagonizing	antagonize	VERB
dti-2185	106	23	β1	β1	NOUN
dti-2185	106	24	-	-	PUNCT
dti-2185	106	25	adrenergic	adrenergic	NOUN
dti-2185	106	26	receptors	receptor	NOUN
dti-2185	106	27	by	by	ADP
dti-2185	106	28	interacting	interact	VERB
dti-2185	106	29	with	with	ADP
dti-2185	106	30	β1	β1	NOUN
dti-2185	106	31	-	-	PUNCT
dti-2185	106	32	adrenergic	adrenergic	ADJ
dti-2185	106	33	receptor	receptor	NOUN
dti-2185	106	34	proteins	protein	NOUN
dti-2185	106	35	,	,	PUNCT
dti-2185	106	36	producing	produce	VERB
dti-2185	106	37	nonselective	nonselective	ADJ
dti-2185	106	38	blockade	blockade	NOUN
dti-2185	106	39	of	of	ADP
dti-2185	106	40	β	β	NOUN
dti-2185	106	41	-	-	ADJ
dti-2185	106	42	adrenergic	adrenergic	ADJ
dti-2185	106	43	receptors	receptor	NOUN
dti-2185	106	44	.	.	PUNCT
dti-2185	107	1	in	in	ADP
dti-2185	107	2	contrast	contrast	NOUN
dti-2185	107	3	,	,	PUNCT
dti-2185	107	4	selective	selective	ADJ
dti-2185	107	5	β1	β1	NOUN
dti-2185	107	6	-	-	PUNCT
dti-2185	107	7	blockers	blocker	NOUN
dti-2185	107	8	do	do	AUX
dti-2185	107	9	not	not	PART
dti-2185	107	10	affect	affect	VERB
dti-2185	107	11	β2	β2	VERB
dti-2185	107	12	-	-	PUNCT
dti-2185	107	13	adrenergic	adrenergic	ADJ
dti-2185	107	14	receptors	receptor	NOUN
dti-2185	107	15	through	through	ADP
dti-2185	107	16	interaction	interaction	NOUN
dti-2185	107	17	with	with	ADP
dti-2185	107	18	lipid	lipid	ADJ
dti-2185	107	19	rafts	raft	NOUN
dti-2185	107	20	,	,	PUNCT
dti-2185	107	21	thereby	thereby	ADV
dti-2185	107	22	enhancing	enhance	VERB
dti-2185	107	23	the	the	DET
dti-2185	107	24	selectivity	selectivity	NOUN
dti-2185	107	25	for	for	ADP
dti-2185	107	26	β1	β1	NOUN
dti-2185	107	27	-	-	PUNCT
dti-2185	107	28	adrenergic	adrenergic	NOUN
dti-2185	107	29	receptors	receptor	NOUN
dti-2185	107	30	.	.	PUNCT
dti-2185	108	1	beta	beta	NOUN
dti-2185	108	2	-	-	PUNCT
dti-2185	108	3	blockers	blocker	NOUN
dti-2185	108	4	,	,	PUNCT
dti-2185	108	5	particularly	particularly	ADV
dti-2185	108	6	β1	β1	NOUN
dti-2185	108	7	-	-	PUNCT
dti-2185	108	8	selective	selective	ADJ
dti-2185	108	9	agents	agent	NOUN
dti-2185	108	10	,	,	PUNCT
dti-2185	108	11	have	have	AUX
dti-2185	108	12	been	be	AUX
dti-2185	108	13	used	use	VERB
dti-2185	108	14	for	for	ADP
dti-2185	108	15	treating	treat	VERB
dti-2185	108	16	hypertension	hypertension	NOUN
dti-2185	108	17	(	(	PUNCT
dti-2185	108	18	54	54	NUM
dti-2185	108	19	)	)	PUNCT
dti-2185	108	20	.	.	PUNCT
dti-2185	109	1	although	although	SCONJ
dti-2185	109	2	the	the	DET
dti-2185	109	3	altered	altered	ADJ
dti-2185	109	4	vascular	vascular	ADJ
dti-2185	109	5	signaling	signal	VERB
dti-2185	109	6	processes	process	NOUN
dti-2185	109	7	are	be	AUX
dti-2185	109	8	implicated	implicate	VERB
dti-2185	109	9	in	in	ADP
dti-2185	109	10	hypertension	hypertension	NOUN
dti-2185	109	11	,	,	PUNCT
dti-2185	109	12	whether	whether	SCONJ
dti-2185	109	13	lipid	lipid	NOUN
dti-2185	109	14	rafts	raft	NOUN
dti-2185	109	15	/	/	SYM
dti-2185	109	16	caveolae	caveolae	NOUN
dti-2185	109	17	are	be	AUX
dti-2185	109	18	responsible	responsible	ADJ
dti-2185	109	19	for	for	ADP
dti-2185	109	20	such	such	ADJ
dti-2185	109	21	pathogenic	pathogenic	ADJ
dti-2185	109	22	events	event	NOUN
dti-2185	109	23	remains	remain	VERB
dti-2185	109	24	unclear	unclear	ADJ
dti-2185	109	25	(	(	PUNCT
dti-2185	109	26	55	55	NUM
dti-2185	109	27	)	)	PUNCT
dti-2185	109	28	,	,	PUNCT
dti-2185	109	29	so	so	CCONJ
dti-2185	109	30	no	no	DET
dti-2185	109	31	significant	significant	ADJ
dti-2185	109	32	interaction	interaction	NOUN
dti-2185	109	33	between	between	ADP
dti-2185	109	34	antihypertensive	antihypertensive	ADJ
dti-2185	109	35	drugs	drug	NOUN
dti-2185	109	36	and	and	CCONJ
dti-2185	109	37	lipid	lipid	NOUN
dti-2185	109	38	rafts	raft	NOUN
dti-2185	109	39	was	be	AUX
dti-2185	109	40	found	find	VERB
dti-2185	109	41	in	in	ADP
dti-2185	109	42	the	the	DET
dti-2185	109	43	literature	literature	NOUN
dti-2185	109	44	.	.	PUNCT
dti-2185	110	1	alpha	alpha	NOUN
dti-2185	110	2	-	-	PUNCT
dti-2185	110	3	adrenergic	adrenergic	ADJ
dti-2185	110	4	agonists	agonist	NOUN
dti-2185	110	5	alpha2	alpha2	NOUN
dti-2185	110	6	-	-	PUNCT
dti-2185	110	7	agonists	agonist	NOUN
dti-2185	110	8	with	with	ADP
dti-2185	110	9	the	the	DET
dti-2185	110	10	sedative	sedative	ADJ
dti-2185	110	11	,	,	PUNCT
dti-2185	110	12	analgesic	analgesic	ADJ
dti-2185	110	13	,	,	PUNCT
dti-2185	110	14	anestheticsparing	anestheticspare	VERB
dti-2185	110	15	and	and	CCONJ
dti-2185	110	16	sympatholytic	sympatholytic	ADJ
dti-2185	110	17	activity	activity	NOUN
dti-2185	110	18	are	be	AUX
dti-2185	110	19	used	use	VERB
dti-2185	110	20	as	as	ADP
dti-2185	110	21	an	an	DET
dti-2185	110	22	adjuvant	adjuvant	NOUN
dti-2185	110	23	for	for	ADP
dti-2185	110	24	anesthesia	anesthesia	PRON
dti-2185	110	25	.	.	PUNCT
dti-2185	111	1	mizogami	mizogami	PROPN
dti-2185	111	2	and	and	CCONJ
dti-2185	111	3	tsuchiya	tsuchiya	PROPN
dti-2185	111	4	performed	perform	VERB
dti-2185	111	5	fp	fp	NOUN
dti-2185	111	6	experiments	experiment	NOUN
dti-2185	111	7	to	to	PART
dti-2185	111	8	investigate	investigate	VERB
dti-2185	111	9	their	their	PRON
dti-2185	111	10	effects	effect	NOUN
dti-2185	111	11	on	on	ADP
dti-2185	111	12	suvs	suvs	NOUN
dti-2185	111	13	that	that	PRON
dti-2185	111	14	were	be	AUX
dti-2185	111	15	prepared	prepare	VERB
dti-2185	111	16	with	with	ADP
dti-2185	111	17	33.3	33.3	NUM
dti-2185	111	18	mol%	mol%	PROPN
dti-2185	111	19	cholesterol	cholesterol	NOUN
dti-2185	111	20	and	and	CCONJ
dti-2185	111	21	66.7	66.7	NUM
dti-2185	111	22	mol%	mol%	PROPN
dti-2185	111	23	phospholipids	phospholipid	NOUN
dti-2185	111	24	(	(	PUNCT
dti-2185	111	25	consisting	consist	VERB
dti-2185	111	26	of	of	ADP
dti-2185	111	27	equimolar	equimolar	NOUN
dti-2185	111	28	dopc	dopc	NOUN
dti-2185	111	29	,	,	PUNCT
dti-2185	111	30	sm	sm	INTJ
dti-2185	111	31	,	,	PUNCT
dti-2185	111	32	pope	pope	NOUN
dti-2185	111	33	and	and	CCONJ
dti-2185	111	34	cb	cb	PROPN
dti-2185	111	35	)	)	PUNCT
dti-2185	111	36	to	to	PART
dti-2185	111	37	be	be	AUX
dti-2185	111	38	raft	raft	NOUN
dti-2185	111	39	model	model	NOUN
dti-2185	111	40	membranes	membrane	NOUN
dti-2185	111	41	and	and	CCONJ
dti-2185	111	42	with	with	ADP
dti-2185	111	43	cholesterol	cholesterol	NOUN
dti-2185	111	44	and	and	CCONJ
dti-2185	111	45	phospholipids	phospholipid	NOUN
dti-2185	111	46	of	of	ADP
dti-2185	111	47	different	different	ADJ
dti-2185	111	48	compositions	composition	NOUN
dti-2185	111	49	to	to	PART
dti-2185	111	50	be	be	AUX
dti-2185	111	51	neuro	neuro	NOUN
dti-2185	111	52	-	-	PUNCT
dti-2185	111	53	mimetic	mimetic	ADJ
dti-2185	111	54	and	and	CCONJ
dti-2185	111	55	cardiomyocyte	cardiomyocyte	NOUN
dti-2185	111	56	-	-	PUNCT
dti-2185	111	57	mimetic	mimetic	ADJ
dti-2185	111	58	membranes	membrane	NOUN
dti-2185	111	59	(	(	PUNCT
dti-2185	111	60	56	56	NUM
dti-2185	111	61	)	)	PUNCT
dti-2185	111	62	.	.	PUNCT
dti-2185	112	1	dexmedetomidine	dexmedetomidine	PROPN
dti-2185	112	2	interacted	interact	VERB
dti-2185	112	3	with	with	ADP
dti-2185	112	4	the	the	DET
dti-2185	112	5	non	non	ADJ
dti-2185	112	6	-	-	ADJ
dti-2185	112	7	raft	raft	ADJ
dti-2185	112	8	membranes	membrane	NOUN
dti-2185	112	9	to	to	PART
dti-2185	112	10	increase	increase	VERB
dti-2185	112	11	their	their	PRON
dti-2185	112	12	fluidity	fluidity	NOUN
dti-2185	112	13	most	most	ADV
dti-2185	112	14	potently	potently	ADV
dti-2185	112	15	at	at	ADP
dti-2185	112	16	5	5	NUM
dti-2185	112	17	-	-	SYM
dti-2185	112	18	200	200	NUM
dti-2185	112	19	μm	μm	NOUN
dti-2185	112	20	,	,	PUNCT
dti-2185	112	21	followed	follow	VERB
dti-2185	112	22	by	by	ADP
dti-2185	112	23	levomedetomidine	levomedetomidine	NOUN
dti-2185	112	24	and	and	CCONJ
dti-2185	112	25	clonidine	clonidine	PROPN
dti-2185	112	26	.	.	PUNCT
dti-2185	113	1	however	however	ADV
dti-2185	113	2	,	,	PUNCT
dti-2185	113	3	these	these	DET
dti-2185	113	4	α2	α2	NOUN
dti-2185	113	5	-	-	PUNCT
dti-2185	113	6	agonists	agonist	NOUN
dti-2185	113	7	exerted	exert	VERB
dti-2185	113	8	much	much	ADV
dti-2185	113	9	weaker	weak	ADJ
dti-2185	113	10	effects	effect	NOUN
dti-2185	113	11	on	on	ADP
dti-2185	113	12	the	the	DET
dti-2185	113	13	raft	raft	NOUN
dti-2185	113	14	model	model	NOUN
dti-2185	113	15	membranes	membrane	NOUN
dti-2185	113	16	so	so	SCONJ
dti-2185	113	17	that	that	SCONJ
dti-2185	113	18	dexmedetomidine	dexmedetomidine	PROPN
dti-2185	113	19	and	and	CCONJ
dti-2185	113	20	levomedetomidine	levomedetomidine	NOUN
dti-2185	113	21	did	do	AUX
dti-2185	113	22	not	not	PART
dti-2185	113	23	show	show	VERB
dti-2185	113	24	large	large	ADJ
dti-2185	113	25	difference	difference	NOUN
dti-2185	113	26	in	in	ADP
dti-2185	113	27	membrane	membrane	NOUN
dti-2185	113	28	interactivity	interactivity	NOUN
dti-2185	113	29	despite	despite	SCONJ
dti-2185	113	30	being	be	AUX
dti-2185	113	31	significantly	significantly	ADV
dti-2185	113	32	different	different	ADJ
dti-2185	113	33	in	in	ADP
dti-2185	113	34	sedative	sedative	ADJ
dti-2185	113	35	activity	activity	NOUN
dti-2185	113	36	between	between	ADP
dti-2185	113	37	medetomidine	medetomidine	ADJ
dti-2185	113	38	enantiomers	enantiomer	NOUN
dti-2185	113	39	.	.	PUNCT
dti-2185	114	1	tsuchiya	tsuchiya	PROPN
dti-2185	114	2	and	and	CCONJ
dti-2185	114	3	mizogami	mizogami	PROPN
dti-2185	114	4	39	39	NUM
dti-2185	114	5	©	©	PROPN
dti-2185	114	6	2020	2020	NUM
dti-2185	114	7	the	the	DET
dti-2185	114	8	authors	author	NOUN
dti-2185	114	9	.	.	PUNCT
dti-2185	115	1	published	publish	VERB
dti-2185	115	2	by	by	ADP
dti-2185	115	3	aboutscience	aboutscience	NOUN
dti-2185	115	4	table	table	NOUN
dti-2185	115	5	iii	iii	NOUN
dti-2185	115	6	interaction	interaction	NOUN
dti-2185	115	7	of	of	ADP
dti-2185	115	8	membranous	membranous	ADJ
dti-2185	115	9	receptorand	receptorand	NOUN
dti-2185	115	10	enzyme	enzyme	NOUN
dti-2185	115	11	-	-	PUNCT
dti-2185	115	12	acting	act	VERB
dti-2185	115	13	drugs	drug	NOUN
dti-2185	115	14	with	with	ADP
dti-2185	115	15	lipid	lipid	NOUN
dti-2185	115	16	raft	raft	NOUN
dti-2185	115	17	membrane	membrane	NOUN
dti-2185	115	18	domains	domain	NOUN
dti-2185	115	19	and	and	CCONJ
dti-2185	115	20	membranes	membrane	NOUN
dti-2185	115	21	drug	drug	NOUN
dti-2185	115	22	class	class	NOUN
dti-2185	115	23	drug	drug	NOUN
dti-2185	115	24	membrane	membrane	NOUN
dti-2185	115	25	induced	induce	VERB
dti-2185	115	26	membrane	membrane	NOUN
dti-2185	115	27	modification	modification	NOUN
dti-2185	115	28	reference	reference	NOUN
dti-2185	115	29	adrenergic	adrenergic	ADJ
dti-2185	115	30	receptor	receptor	NOUN
dti-2185	115	31	-	-	PUNCT
dti-2185	115	32	acting	act	VERB
dti-2185	115	33	drug	drug	NOUN
dti-2185	115	34	nonselective	nonselective	ADJ
dti-2185	115	35	β	β	NOUN
dti-2185	115	36	-	-	NOUN
dti-2185	115	37	blockers	blocker	NOUN
dti-2185	115	38	(	(	PUNCT
dti-2185	115	39	0.2	0.2	NUM
dti-2185	115	40	and	and	CCONJ
dti-2185	115	41	1	1	NUM
dti-2185	115	42	mm	mm	NOUN
dti-2185	115	43	)	)	PUNCT
dti-2185	115	44	selective	selective	ADJ
dti-2185	115	45	β1	β1	NOUN
dti-2185	115	46	-	-	PUNCT
dti-2185	115	47	blockers	blocker	NOUN
dti-2185	115	48	(	(	PUNCT
dti-2185	115	49	0.2	0.2	NUM
dti-2185	115	50	and	and	CCONJ
dti-2185	115	51	1	1	NUM
dti-2185	115	52	mm	mm	NOUN
dti-2185	115	53	)	)	PUNCT
dti-2185	115	54	suvs	suvs	NOUN
dti-2185	115	55	(	(	PUNCT
dti-2185	115	56	popc	popc	NOUN
dti-2185	115	57	,	,	PUNCT
dti-2185	115	58	sm	sm	PROPN
dti-2185	115	59	,	,	PUNCT
dti-2185	115	60	pope	pope	PROPN
dti-2185	115	61	,	,	PUNCT
dti-2185	115	62	cb	cb	PROPN
dti-2185	115	63	and	and	CCONJ
dti-2185	115	64	cholesterol	cholesterol	PROPN
dti-2185	115	65	,	,	PUNCT
dti-2185	115	66	1:1:1:1:2	1:1:1:1:2	NUM
dti-2185	115	67	molar	molar	ADJ
dti-2185	115	68	ratio	ratio	NOUN
dti-2185	115	69	)	)	PUNCT
dti-2185	115	70	nonselective	nonselective	ADJ
dti-2185	115	71	propranolol	propranolol	NOUN
dti-2185	115	72	most	most	ADV
dti-2185	115	73	potently	potently	ADV
dti-2185	115	74	increased	increase	VERB
dti-2185	115	75	the	the	DET
dti-2185	115	76	membrane	membrane	NOUN
dti-2185	115	77	fluidity	fluidity	NOUN
dti-2185	115	78	,	,	PUNCT
dti-2185	115	79	followed	follow	VERB
dti-2185	115	80	by	by	ADP
dti-2185	115	81	alprenolol	alprenolol	NOUN
dti-2185	115	82	and	and	CCONJ
dti-2185	115	83	oxprenolol	oxprenolol	NOUN
dti-2185	115	84	,	,	PUNCT
dti-2185	115	85	but	but	CCONJ
dti-2185	115	86	not	not	PART
dti-2185	115	87	β1	β1	VERB
dti-2185	115	88	-	-	PUNCT
dti-2185	115	89	selective	selective	ADJ
dti-2185	115	90	atenolol	atenolol	PROPN
dti-2185	115	91	,	,	PUNCT
dti-2185	115	92	metoprolol	metoprolol	PROPN
dti-2185	115	93	and	and	CCONJ
dti-2185	115	94	esmolol	esmolol	VERB
dti-2185	115	95	52	52	NUM
dti-2185	115	96	adrenergic	adrenergic	ADJ
dti-2185	115	97	receptor	receptor	NOUN
dti-2185	115	98	-	-	PUNCT
dti-2185	115	99	acting	act	VERB
dti-2185	115	100	drug	drug	NOUN
dti-2185	115	101	nonselective	nonselective	ADJ
dti-2185	115	102	β	β	NOUN
dti-2185	115	103	-	-	NOUN
dti-2185	115	104	blockers	blocker	NOUN
dti-2185	115	105	(	(	PUNCT
dti-2185	115	106	20	20	NUM
dti-2185	115	107	-	-	SYM
dti-2185	115	108	200	200	NUM
dti-2185	115	109	μm	μm	NOUN
dti-2185	115	110	)	)	PUNCT
dti-2185	115	111	selective	selective	ADJ
dti-2185	115	112	β1	β1	NOUN
dti-2185	115	113	-	-	PUNCT
dti-2185	115	114	blockers	blocker	NOUN
dti-2185	115	115	(	(	PUNCT
dti-2185	115	116	20	20	NUM
dti-2185	115	117	-	-	SYM
dti-2185	115	118	200	200	NUM
dti-2185	115	119	μm	μm	NUM
dti-2185	115	120	)	)	PUNCT
dti-2185	115	121	suvs	suvs	NOUN
dti-2185	115	122	(	(	PUNCT
dti-2185	115	123	33.3	33.3	NUM
dti-2185	115	124	mol%	mol%	PROPN
dti-2185	115	125	cholesterol	cholesterol	NOUN
dti-2185	115	126	and	and	CCONJ
dti-2185	115	127	66.7	66.7	NUM
dti-2185	115	128	mol%	mol%	PROPN
dti-2185	115	129	phospholipids	phospholipid	NOUN
dti-2185	115	130	of	of	ADP
dti-2185	115	131	equimolar	equimolar	NOUN
dti-2185	115	132	dopc	dopc	NOUN
dti-2185	115	133	,	,	PUNCT
dti-2185	115	134	sm	sm	INTJ
dti-2185	115	135	,	,	PUNCT
dti-2185	115	136	pope	pope	NOUN
dti-2185	115	137	and	and	CCONJ
dti-2185	115	138	cb	cb	PROPN
dti-2185	115	139	)	)	PUNCT
dti-2185	115	140	nonselective	nonselective	ADJ
dti-2185	115	141	propranolol	propranolol	NOUN
dti-2185	115	142	and	and	CCONJ
dti-2185	115	143	alprenolol	alprenolol	NOUN
dti-2185	115	144	increased	increase	VERB
dti-2185	115	145	the	the	DET
dti-2185	115	146	membrane	membrane	NOUN
dti-2185	115	147	fluidity	fluidity	NOUN
dti-2185	115	148	,	,	PUNCT
dti-2185	115	149	but	but	CCONJ
dti-2185	115	150	not	not	PART
dti-2185	115	151	β1	β1	VERB
dti-2185	115	152	-	-	PUNCT
dti-2185	115	153	selective	selective	ADJ
dti-2185	115	154	landiolol	landiolol	NOUN
dti-2185	115	155	and	and	CCONJ
dti-2185	115	156	esmolol	esmolol	VERB
dti-2185	115	157	53	53	NUM
dti-2185	115	158	adrenergic	adrenergic	ADJ
dti-2185	115	159	receptor	receptor	NOUN
dti-2185	115	160	-	-	PUNCT
dti-2185	115	161	acting	act	VERB
dti-2185	115	162	drug	drug	NOUN
dti-2185	115	163	alpha2	alpha2	NOUN
dti-2185	115	164	-	-	PUNCT
dti-2185	115	165	agonists	agonist	NOUN
dti-2185	115	166	(	(	PUNCT
dti-2185	115	167	5	5	NUM
dti-2185	115	168	-	-	SYM
dti-2185	115	169	200	200	NUM
dti-2185	115	170	μm	μm	NUM
dti-2185	115	171	)	)	PUNCT
dti-2185	115	172	suvs	suvs	NOUN
dti-2185	115	173	(	(	PUNCT
dti-2185	115	174	33.3	33.3	NUM
dti-2185	115	175	mol%	mol%	PROPN
dti-2185	115	176	cholesterol	cholesterol	NOUN
dti-2185	115	177	and	and	CCONJ
dti-2185	115	178	66.7	66.7	NUM
dti-2185	115	179	mol%	mol%	PROPN
dti-2185	115	180	phospholipids	phospholipid	NOUN
dti-2185	115	181	(	(	PUNCT
dti-2185	115	182	dopc	dopc	NOUN
dti-2185	115	183	,	,	PUNCT
dti-2185	115	184	sm	sm	PROPN
dti-2185	115	185	,	,	PUNCT
dti-2185	115	186	pope	pope	NOUN
dti-2185	115	187	and	and	CCONJ
dti-2185	115	188	cb	cb	PROPN
dti-2185	115	189	)	)	PUNCT
dti-2185	115	190	)	)	PUNCT
dti-2185	115	191	dexmedetomidine	dexmedetomidine	PROPN
dti-2185	115	192	increased	increase	VERB
dti-2185	115	193	the	the	DET
dti-2185	115	194	fluidity	fluidity	NOUN
dti-2185	115	195	of	of	ADP
dti-2185	115	196	non	non	ADJ
dti-2185	115	197	-	-	ADJ
dti-2185	115	198	raft	raft	ADJ
dti-2185	115	199	membranes	membrane	NOUN
dti-2185	115	200	most	most	ADV
dti-2185	115	201	potently	potently	ADV
dti-2185	115	202	,	,	PUNCT
dti-2185	115	203	followed	follow	VERB
dti-2185	115	204	by	by	ADP
dti-2185	115	205	levomedetomidine	levomedetomidine	NOUN
dti-2185	115	206	and	and	CCONJ
dti-2185	115	207	clonidine	clonidine	NOUN
dti-2185	115	208	,	,	PUNCT
dti-2185	115	209	although	although	SCONJ
dti-2185	115	210	the	the	DET
dti-2185	115	211	effects	effect	NOUN
dti-2185	115	212	on	on	ADP
dti-2185	115	213	raft	raft	NOUN
dti-2185	115	214	model	model	NOUN
dti-2185	115	215	membranes	membrane	NOUN
dti-2185	115	216	were	be	AUX
dti-2185	115	217	much	much	ADV
dti-2185	115	218	weaker	weak	ADJ
dti-2185	115	219	without	without	ADP
dti-2185	115	220	showing	show	VERB
dti-2185	115	221	large	large	ADJ
dti-2185	115	222	difference	difference	NOUN
dti-2185	115	223	between	between	ADP
dti-2185	115	224	medetomidine	medetomidine	ADJ
dti-2185	115	225	enantiomers	enantiomer	NOUN
dti-2185	115	226	56	56	NUM
dti-2185	115	227	opioid	opioid	ADJ
dti-2185	115	228	receptoracting	receptoracte	VERB
dti-2185	115	229	drug	drug	NOUN
dti-2185	115	230	rats	rat	NOUN
dti-2185	115	231	injected	inject	VERB
dti-2185	115	232	with	with	ADP
dti-2185	115	233	morphine	morphine	NOUN
dti-2185	115	234	(	(	PUNCT
dti-2185	115	235	25	25	NUM
dti-2185	115	236	mg	mg	PROPN
dti-2185	115	237	/	/	SYM
dti-2185	115	238	kg	kg	PROPN
dti-2185	115	239	,	,	PUNCT
dti-2185	115	240	i.p	i.p	PROPN
dti-2185	115	241	.	.	PUNCT
dti-2185	115	242	)	)	PUNCT
dti-2185	116	1	rats	rat	NOUN
dti-2185	116	2	injected	inject	VERB
dti-2185	116	3	with	with	ADP
dti-2185	116	4	naloxone	naloxone	NOUN
dti-2185	116	5	(	(	PUNCT
dti-2185	116	6	2	2	NUM
dti-2185	116	7	mg	mg	PROPN
dti-2185	116	8	/	/	SYM
dti-2185	116	9	kg	kg	PROPN
dti-2185	116	10	,	,	PUNCT
dti-2185	116	11	i.p	i.p	PROPN
dti-2185	116	12	.	.	PROPN
dti-2185	116	13	)	)	PUNCT
dti-2185	116	14	morphine	morphine	NOUN
dti-2185	116	15	(	(	PUNCT
dti-2185	116	16	10	10	NUM
dti-2185	116	17	nm	nm	NOUN
dti-2185	116	18	and	and	CCONJ
dti-2185	116	19	10	10	NUM
dti-2185	116	20	μm	μm	NOUN
dti-2185	116	21	)	)	PUNCT
dti-2185	116	22	naloxone	naloxone	NOUN
dti-2185	116	23	(	(	PUNCT
dti-2185	116	24	1	1	NUM
dti-2185	116	25	nm	nm	NOUN
dti-2185	116	26	)	)	PUNCT
dti-2185	116	27	hippocampus	hippocampus	NOUN
dti-2185	116	28	and	and	CCONJ
dti-2185	116	29	caudate	caudate	ADJ
dti-2185	116	30	membranes	membrane	NOUN
dti-2185	116	31	hippocampus	hippocampus	NOUN
dti-2185	116	32	and	and	CCONJ
dti-2185	116	33	caudate	caudate	ADJ
dti-2185	116	34	membranes	membrane	NOUN
dti-2185	116	35	rat	rat	NOUN
dti-2185	116	36	brain	brain	NOUN
dti-2185	116	37	membrane	membrane	NOUN
dti-2185	116	38	preparations	preparation	NOUN
dti-2185	116	39	rat	rat	NOUN
dti-2185	116	40	brain	brain	NOUN
dti-2185	116	41	membrane	membrane	NOUN
dti-2185	116	42	preparations	preparation	NOUN
dti-2185	116	43	increased	increase	VERB
dti-2185	116	44	the	the	DET
dti-2185	116	45	membrane	membrane	NOUN
dti-2185	116	46	fluidity	fluidity	NOUN
dti-2185	116	47	decreased	decrease	VERB
dti-2185	116	48	the	the	DET
dti-2185	116	49	membrane	membrane	NOUN
dti-2185	116	50	fluidity	fluidity	NOUN
dti-2185	116	51	increased	increase	VERB
dti-2185	116	52	the	the	DET
dti-2185	116	53	membrane	membrane	NOUN
dti-2185	116	54	fluidity	fluidity	NOUN
dti-2185	116	55	reversed	reverse	VERB
dti-2185	116	56	the	the	DET
dti-2185	116	57	membrane	membrane	NOUN
dti-2185	116	58	-	-	PUNCT
dti-2185	116	59	fluidizing	fluidize	VERB
dti-2185	116	60	effects	effect	NOUN
dti-2185	116	61	of	of	ADP
dti-2185	116	62	10	10	NUM
dti-2185	116	63	nm	nm	ADJ
dti-2185	116	64	morphine	morphine	NOUN
dti-2185	116	65	59	59	NUM
dti-2185	116	66	opioid	opioid	NOUN
dti-2185	116	67	receptoracting	receptoracte	VERB
dti-2185	116	68	drug	drug	NOUN
dti-2185	116	69	codeine	codeine	NOUN
dti-2185	116	70	(	(	PUNCT
dti-2185	116	71	0.1	0.1	NUM
dti-2185	116	72	m	m	NOUN
dti-2185	116	73	)	)	PUNCT
dti-2185	116	74	n	n	CCONJ
dti-2185	116	75	-	-	PUNCT
dti-2185	116	76	methylcodeine	methylcodeine	NOUN
dti-2185	116	77	(	(	PUNCT
dti-2185	116	78	0.1	0.1	NUM
dti-2185	116	79	m	m	NOUN
dti-2185	116	80	)	)	PUNCT
dti-2185	116	81	dppc	dppc	VERB
dti-2185	116	82	mlvs	mlvs	ADV
dti-2185	116	83	reduced	reduce	VERB
dti-2185	116	84	the	the	DET
dti-2185	116	85	phase	phase	NOUN
dti-2185	116	86	transition	transition	NOUN
dti-2185	116	87	temperature	temperature	NOUN
dti-2185	116	88	60	60	NUM
dti-2185	116	89	opioid	opioid	ADJ
dti-2185	116	90	receptoracting	receptoracte	VERB
dti-2185	116	91	drug	drug	NOUN
dti-2185	116	92	etorphine	etorphine	NOUN
dti-2185	116	93	(	(	PUNCT
dti-2185	116	94	10	10	NUM
dti-2185	116	95	nm	nm	NOUN
dti-2185	116	96	)	)	PUNCT
dti-2185	116	97	mice	mouse	NOUN
dti-2185	116	98	injected	inject	VERB
dti-2185	116	99	with	with	ADP
dti-2185	116	100	etorphine	etorphine	NOUN
dti-2185	116	101	(	(	PUNCT
dti-2185	116	102	5	5	NUM
dti-2185	116	103	μg	μg	PROPN
dti-2185	116	104	/	/	SYM
dti-2185	116	105	kg	kg	PROPN
dti-2185	116	106	,	,	PUNCT
dti-2185	116	107	s.c	s.c	PROPN
dti-2185	116	108	.	.	PROPN
dti-2185	116	109	)	)	PUNCT
dti-2185	117	1	human	human	ADJ
dti-2185	117	2	embryonic	embryonic	ADJ
dti-2185	117	3	kidney	kidney	NOUN
dti-2185	117	4	cells	cell	NOUN
dti-2185	117	5	expressing	express	VERB
dti-2185	117	6	μ	μ	NOUN
dti-2185	117	7	-	-	PUNCT
dti-2185	117	8	receptors	receptor	NOUN
dti-2185	117	9	hippocampi	hippocampi	ADJ
dti-2185	117	10	isolated	isolate	VERB
dti-2185	117	11	after	after	SCONJ
dti-2185	117	12	drug	drug	NOUN
dti-2185	117	13	injection	injection	NOUN
dti-2185	117	14	translated	translate	VERB
dti-2185	117	15	μ	μ	NOUN
dti-2185	117	16	-	-	NOUN
dti-2185	117	17	receptors	receptor	NOUN
dti-2185	117	18	from	from	ADP
dti-2185	117	19	lipid	lipid	ADJ
dti-2185	117	20	rafts	raft	NOUN
dti-2185	117	21	to	to	ADP
dti-2185	117	22	non	non	ADJ
dti-2185	117	23	-	-	ADJ
dti-2185	117	24	raft	raft	ADJ
dti-2185	117	25	regions	region	NOUN
dti-2185	117	26	61	61	NUM
dti-2185	117	27	cyclooxygenaseacting	cyclooxygenaseacting	NOUN
dti-2185	117	28	antiinflammatory	antiinflammatory	NOUN
dti-2185	117	29	drug	drug	NOUN
dti-2185	117	30	aspirin	aspirin	NOUN
dti-2185	117	31	(	(	PUNCT
dti-2185	117	32	3	3	NUM
dti-2185	117	33	mm	mm	NOUN
dti-2185	117	34	)	)	PUNCT
dti-2185	117	35	dppc	dppc	NOUN
dti-2185	117	36	bilayer	bilayer	NOUN
dti-2185	117	37	membranes	membrane	NOUN
dti-2185	117	38	containing	contain	VERB
dti-2185	117	39	32.5	32.5	NUM
dti-2185	117	40	mol%	mol%	PROPN
dti-2185	117	41	cholesterol	cholesterol	NOUN
dti-2185	117	42	increased	increase	VERB
dti-2185	117	43	the	the	DET
dti-2185	117	44	membrane	membrane	NOUN
dti-2185	117	45	fluidity	fluidity	NOUN
dti-2185	117	46	disrupted	disrupt	VERB
dti-2185	117	47	the	the	DET
dti-2185	117	48	membrane	membrane	NOUN
dti-2185	117	49	organization	organization	NOUN
dti-2185	117	50	and	and	CCONJ
dti-2185	117	51	prevented	prevent	VERB
dti-2185	117	52	raft	raft	NOUN
dti-2185	117	53	formation	formation	NOUN
dti-2185	117	54	63	63	NUM
dti-2185	117	55	cyclooxygenaseacting	cyclooxygenaseacte	VERB
dti-2185	117	56	antiinflammatory	antiinflammatory	NOUN
dti-2185	117	57	drug	drug	NOUN
dti-2185	117	58	aspirin	aspirin	NOUN
dti-2185	117	59	(	(	PUNCT
dti-2185	117	60	10	10	NUM
dti-2185	117	61	mol%	mol%	NOUN
dti-2185	117	62	)	)	PUNCT
dti-2185	117	63	mlvs	mlvs	NOUN
dti-2185	117	64	(	(	PUNCT
dti-2185	117	65	70	70	NUM
dti-2185	117	66	mol%	mol%	PROPN
dti-2185	117	67	dmpc	dmpc	NOUN
dti-2185	117	68	and	and	CCONJ
dti-2185	117	69	30	30	NUM
dti-2185	117	70	mol%	mol%	PROPN
dti-2185	117	71	cholesterol	cholesterol	NOUN
dti-2185	117	72	)	)	PUNCT
dti-2185	117	73	bound	bind	VERB
dti-2185	117	74	to	to	ADP
dti-2185	117	75	raft	raft	VERB
dti-2185	117	76	-	-	PUNCT
dti-2185	117	77	like	like	ADJ
dti-2185	117	78	lo	lo	NOUN
dti-2185	117	79	phase	phase	NOUN
dti-2185	117	80	domains	domain	NOUN
dti-2185	117	81	and	and	CCONJ
dti-2185	117	82	disturbed	disturb	VERB
dti-2185	117	83	their	their	PRON
dti-2185	117	84	organization	organization	NOUN
dti-2185	117	85	64	64	NUM
dti-2185	117	86	cyclooxygenaseacting	cyclooxygenaseacte	VERB
dti-2185	117	87	antiinflammatory	antiinflammatory	NOUN
dti-2185	117	88	drug	drug	NOUN
dti-2185	117	89	indomethacin	indomethacin	NOUN
dti-2185	117	90	(	(	PUNCT
dti-2185	117	91	5	5	NUM
dti-2185	117	92	μm	μm	NOUN
dti-2185	117	93	)	)	PUNCT
dti-2185	117	94	naproxen	naproxen	NOUN
dti-2185	117	95	(	(	PUNCT
dti-2185	117	96	25	25	NUM
dti-2185	117	97	μm	μm	NUM
dti-2185	117	98	)	)	PUNCT
dti-2185	117	99	aspirin	aspirin	NOUN
dti-2185	117	100	(	(	PUNCT
dti-2185	117	101	50	50	NUM
dti-2185	117	102	μm	μm	NOUN
dti-2185	117	103	)	)	PUNCT
dti-2185	117	104	ibuprofen	ibuprofen	NOUN
dti-2185	117	105	(	(	PUNCT
dti-2185	117	106	150	150	NUM
dti-2185	117	107	μm	μm	NOUN
dti-2185	117	108	)	)	PUNCT
dti-2185	117	109	baby	baby	NOUN
dti-2185	117	110	hamster	hamster	NOUN
dti-2185	117	111	kidney	kidney	NOUN
dti-2185	117	112	cells	cell	NOUN
dti-2185	117	113	affected	affect	VERB
dti-2185	117	114	the	the	DET
dti-2185	117	115	organization	organization	NOUN
dti-2185	117	116	of	of	ADP
dti-2185	117	117	raft	raft	NOUN
dti-2185	117	118	-	-	PUNCT
dti-2185	117	119	like	like	ADJ
dti-2185	117	120	ordered	order	VERB
dti-2185	117	121	lipid	lipid	NOUN
dti-2185	117	122	and	and	CCONJ
dti-2185	117	123	protein	protein	NOUN
dti-2185	117	124	membrane	membrane	NOUN
dti-2185	117	125	nanoclusters	nanocluster	NOUN
dti-2185	117	126	65	65	NUM
dti-2185	117	127	cb	cb	NOUN
dti-2185	117	128	=	=	PUNCT
dti-2185	117	129	cerebroside	cerebroside	NOUN
dti-2185	117	130	;	;	PUNCT
dti-2185	117	131	dmpc	dmpc	NOUN
dti-2185	117	132	=	=	SYM
dti-2185	117	133	1,2	1,2	NUM
dti-2185	117	134	-	-	PUNCT
dti-2185	117	135	dimyristoylphosphatidylcholine	dimyristoylphosphatidylcholine	NOUN
dti-2185	117	136	;	;	PUNCT
dti-2185	117	137	dopc	dopc	NOUN
dti-2185	117	138	=	=	SYM
dti-2185	117	139	1,2	1,2	NUM
dti-2185	117	140	-	-	PUNCT
dti-2185	117	141	dioleoylphosphatidylcholine	dioleoylphosphatidylcholine	NOUN
dti-2185	117	142	;	;	PUNCT
dti-2185	117	143	dppc	dppc	NOUN
dti-2185	117	144	=	=	SYM
dti-2185	117	145	1,2	1,2	NUM
dti-2185	117	146	-	-	NUM
dti-2185	117	147	dipalmitoylphosphatidylcholine	dipalmitoylphosphatidylcholine	ADJ
dti-2185	117	148	;	;	PUNCT
dti-2185	117	149	mlv	mlv	ADJ
dti-2185	117	150	=	=	SYM
dti-2185	117	151	multilamellar	multilamellar	ADJ
dti-2185	117	152	vesicle	vesicle	NOUN
dti-2185	117	153	;	;	PUNCT
dti-2185	117	154	popc	popc	NOUN
dti-2185	117	155	=	=	SYM
dti-2185	117	156	1	1	NUM
dti-2185	117	157	-	-	PUNCT
dti-2185	117	158	palmitoyl-2	palmitoyl-2	VERB
dti-2185	117	159	-	-	PUNCT
dti-2185	117	160	oleoylphosphatidylcholine	oleoylphosphatidylcholine	NOUN
dti-2185	117	161	;	;	PUNCT
dti-2185	117	162	pope	pope	NOUN
dti-2185	117	163	=	=	SYM
dti-2185	117	164	1	1	NUM
dti-2185	117	165	-	-	PUNCT
dti-2185	117	166	palmitoyl-2	palmitoyl-2	VERB
dti-2185	117	167	-	-	PUNCT
dti-2185	117	168	oleoylphosphatidylethanolamine	oleoylphosphatidylethanolamine	NOUN
dti-2185	117	169	;	;	PUNCT
dti-2185	117	170	sm	sm	PROPN
dti-2185	117	171	=	=	SYM
dti-2185	117	172	sphingomyelin	sphingomyelin	NOUN
dti-2185	117	173	;	;	PUNCT
dti-2185	117	174	suv	suv	X
dti-2185	117	175	=	=	SYM
dti-2185	117	176	small	small	ADJ
dti-2185	117	177	unilamellar	unilamellar	ADJ
dti-2185	117	178	vesicle	vesicle	NOUN
dti-2185	117	179	.	.	PUNCT
dti-2185	118	1	interaction	interaction	NOUN
dti-2185	118	2	of	of	ADP
dti-2185	118	3	drugs	drug	NOUN
dti-2185	118	4	with	with	ADP
dti-2185	118	5	lipid	lipid	ADJ
dti-2185	118	6	rafts40	rafts40	NOUN
dti-2185	119	1	©	©	PROPN
dti-2185	119	2	2020	2020	NUM
dti-2185	120	1	the	the	DET
dti-2185	120	2	authors	author	NOUN
dti-2185	120	3	.	.	PUNCT
dti-2185	120	4	published	publish	VERB
dti-2185	120	5	by	by	ADP
dti-2185	120	6	aboutscience	aboutscience	NOUN
dti-2185	120	7	the	the	DET
dti-2185	120	8	mechanistic	mechanistic	ADJ
dti-2185	120	9	relevance	relevance	NOUN
dti-2185	120	10	of	of	ADP
dti-2185	120	11	lipid	lipid	ADJ
dti-2185	120	12	rafts	raft	NOUN
dti-2185	120	13	to	to	ADP
dti-2185	120	14	the	the	DET
dti-2185	120	15	enantioselective	enantioselective	ADJ
dti-2185	120	16	effects	effect	NOUN
dti-2185	120	17	of	of	ADP
dti-2185	120	18	α2	α2	NOUN
dti-2185	120	19	-	-	PUNCT
dti-2185	120	20	agonists	agonist	NOUN
dti-2185	120	21	is	be	AUX
dti-2185	120	22	inconclusive	inconclusive	ADJ
dti-2185	120	23	as	as	SCONJ
dti-2185	120	24	morris	morris	PROPN
dti-2185	120	25	et	et	PROPN
dti-2185	120	26	al	al	PROPN
dti-2185	120	27	reported	report	VERB
dti-2185	120	28	that	that	SCONJ
dti-2185	120	29	α1	α1	ADJ
dti-2185	120	30	-	-	PUNCT
dti-2185	120	31	adrenergic	adrenergic	ADJ
dti-2185	120	32	receptors	receptor	NOUN
dti-2185	120	33	,	,	PUNCT
dti-2185	120	34	but	but	CCONJ
dti-2185	120	35	not	not	PART
dti-2185	120	36	α2	α2	ADJ
dti-2185	120	37	-	-	PUNCT
dti-2185	120	38	adrenergic	adrenergic	NOUN
dti-2185	120	39	receptors	receptor	NOUN
dti-2185	120	40	,	,	PUNCT
dti-2185	120	41	occupy	occupy	VERB
dti-2185	120	42	membrane	membrane	NOUN
dti-2185	120	43	lipid	lipid	NOUN
dti-2185	120	44	rafts	raft	NOUN
dti-2185	120	45	(	(	PUNCT
dti-2185	120	46	57	57	NUM
dti-2185	120	47	)	)	PUNCT
dti-2185	120	48	.	.	PUNCT
dti-2185	121	1	opioid	opioid	ADJ
dti-2185	121	2	analgesics	analgesic	NOUN
dti-2185	121	3	morphine	morphine	NOUN
dti-2185	121	4	and	and	CCONJ
dti-2185	121	5	its	its	PRON
dti-2185	121	6	related	relate	VERB
dti-2185	121	7	drugs	drug	NOUN
dti-2185	121	8	act	act	VERB
dti-2185	121	9	on	on	ADP
dti-2185	121	10	inhibitory	inhibitory	ADJ
dti-2185	121	11	opioid	opioid	ADJ
dti-2185	121	12	receptors	receptor	NOUN
dti-2185	121	13	of	of	ADP
dti-2185	121	14	μ	μ	NUM
dti-2185	121	15	,	,	PUNCT
dti-2185	121	16	κ	κ	PROPN
dti-2185	121	17	and	and	CCONJ
dti-2185	121	18	δ	δ	PROPN
dti-2185	121	19	subtypes	subtype	NOUN
dti-2185	121	20	expressed	express	VERB
dti-2185	121	21	in	in	ADP
dti-2185	121	22	nociceptive	nociceptive	ADJ
dti-2185	121	23	neuronal	neuronal	ADJ
dti-2185	121	24	circuits	circuit	NOUN
dti-2185	121	25	.	.	PUNCT
dti-2185	122	1	mu	mu	NOUN
dti-2185	122	2	-	-	PUNCT
dti-2185	122	3	receptors	receptor	NOUN
dti-2185	122	4	responsible	responsible	ADJ
dti-2185	122	5	for	for	ADP
dti-2185	122	6	the	the	DET
dti-2185	122	7	effects	effect	NOUN
dti-2185	122	8	of	of	ADP
dti-2185	122	9	opioid	opioid	ADJ
dti-2185	122	10	analgesics	analgesic	NOUN
dti-2185	122	11	and	and	CCONJ
dti-2185	122	12	antagonists	antagonist	NOUN
dti-2185	122	13	are	be	AUX
dti-2185	122	14	located	locate	VERB
dti-2185	122	15	within	within	ADP
dti-2185	122	16	lipid	lipid	NOUN
dti-2185	122	17	raft	raft	NOUN
dti-2185	122	18	/	/	SYM
dti-2185	122	19	caveola	caveola	NOUN
dti-2185	122	20	membrane	membrane	NOUN
dti-2185	122	21	domains	domain	NOUN
dti-2185	122	22	(	(	PUNCT
dti-2185	122	23	58	58	NUM
dti-2185	122	24	)	)	PUNCT
dti-2185	122	25	.	.	PUNCT
dti-2185	123	1	heron	heron	PROPN
dti-2185	123	2	et	et	PROPN
dti-2185	123	3	al	al	PROPN
dti-2185	123	4	performed	perform	VERB
dti-2185	123	5	in	in	ADP
dti-2185	123	6	vivo	vivo	ADJ
dti-2185	123	7	experiments	experiment	NOUN
dti-2185	123	8	to	to	PART
dti-2185	123	9	inject	inject	VERB
dti-2185	123	10	rats	rat	NOUN
dti-2185	123	11	with	with	ADP
dti-2185	123	12	opioids	opioid	NOUN
dti-2185	123	13	intraperitoneally	intraperitoneally	ADV
dti-2185	123	14	and	and	CCONJ
dti-2185	123	15	in	in	ADP
dti-2185	123	16	vitro	vitro	X
dti-2185	123	17	experiments	experiment	NOUN
dti-2185	123	18	to	to	ADP
dti-2185	123	19	subject	subject	ADJ
dti-2185	123	20	membranes	membrane	NOUN
dti-2185	123	21	prepared	prepare	VERB
dti-2185	123	22	from	from	ADP
dti-2185	123	23	rat	rat	NOUN
dti-2185	123	24	brains	brain	NOUN
dti-2185	123	25	to	to	ADP
dti-2185	123	26	the	the	DET
dti-2185	123	27	reaction	reaction	NOUN
dti-2185	123	28	with	with	ADP
dti-2185	123	29	opioids	opioid	NOUN
dti-2185	123	30	,	,	PUNCT
dti-2185	123	31	followed	follow	VERB
dti-2185	123	32	by	by	ADP
dti-2185	123	33	fp	fp	NOUN
dti-2185	123	34	measurements	measurement	NOUN
dti-2185	123	35	(	(	PUNCT
dti-2185	123	36	59	59	NUM
dti-2185	123	37	)	)	PUNCT
dti-2185	123	38	.	.	PUNCT
dti-2185	124	1	morphine	morphine	PROPN
dti-2185	124	2	increased	increase	VERB
dti-2185	124	3	the	the	DET
dti-2185	124	4	fluidity	fluidity	NOUN
dti-2185	124	5	of	of	ADP
dti-2185	124	6	hippocampus	hippocampus	NOUN
dti-2185	124	7	and	and	CCONJ
dti-2185	124	8	caudate	caudate	ADJ
dti-2185	124	9	membranes	membrane	NOUN
dti-2185	124	10	from	from	ADP
dti-2185	124	11	rats	rat	NOUN
dti-2185	124	12	injected	inject	VERB
dti-2185	124	13	at	at	ADP
dti-2185	124	14	25	25	NUM
dti-2185	124	15	mg	mg	PROPN
dti-2185	124	16	/	/	SYM
dti-2185	124	17	kg	kg	PROPN
dti-2185	124	18	(	(	PUNCT
dti-2185	124	19	i.p	i.p	PROPN
dti-2185	124	20	.	.	PROPN
dti-2185	124	21	)	)	PUNCT
dti-2185	125	1	and	and	CCONJ
dti-2185	125	2	the	the	DET
dti-2185	125	3	fluidity	fluidity	NOUN
dti-2185	125	4	of	of	ADP
dti-2185	125	5	the	the	DET
dti-2185	125	6	membrane	membrane	NOUN
dti-2185	125	7	preparations	preparation	NOUN
dti-2185	125	8	at	at	ADP
dti-2185	125	9	10	10	NUM
dti-2185	125	10	nm	nm	NOUN
dti-2185	125	11	and	and	CCONJ
dti-2185	125	12	10	10	NUM
dti-2185	125	13	μm	μm	NOUN
dti-2185	125	14	.	.	PUNCT
dti-2185	126	1	in	in	ADP
dti-2185	126	2	contrast	contrast	NOUN
dti-2185	126	3	,	,	PUNCT
dti-2185	126	4	opioid	opioid	ADJ
dti-2185	126	5	antagonist	antagonist	NOUN
dti-2185	126	6	naloxone	naloxone	NOUN
dti-2185	126	7	decreased	decrease	VERB
dti-2185	126	8	the	the	DET
dti-2185	126	9	membrane	membrane	NOUN
dti-2185	126	10	fluidity	fluidity	NOUN
dti-2185	126	11	of	of	ADP
dti-2185	126	12	the	the	DET
dti-2185	126	13	same	same	ADJ
dti-2185	126	14	brain	brain	NOUN
dti-2185	126	15	regions	region	NOUN
dti-2185	126	16	at	at	ADP
dti-2185	126	17	2	2	NUM
dti-2185	126	18	mg	mg	PROPN
dti-2185	126	19	/	/	SYM
dti-2185	126	20	kg	kg	PROPN
dti-2185	126	21	(	(	PUNCT
dti-2185	126	22	i.p	i.p	PROPN
dti-2185	126	23	.	.	PROPN
dti-2185	126	24	)	)	PUNCT
dti-2185	126	25	and	and	CCONJ
dti-2185	126	26	reversed	reverse	VERB
dti-2185	126	27	the	the	DET
dti-2185	126	28	in	in	ADV
dti-2185	126	29	vitro	vitro	X
dti-2185	126	30	membrane	membrane	NOUN
dti-2185	126	31	-	-	PUNCT
dti-2185	126	32	fluidizing	fluidize	VERB
dti-2185	126	33	effect	effect	NOUN
dti-2185	126	34	of	of	ADP
dti-2185	126	35	10	10	NUM
dti-2185	126	36	nm	nm	ADJ
dti-2185	126	37	morphine	morphine	NOUN
dti-2185	126	38	at	at	ADP
dti-2185	126	39	1	1	NUM
dti-2185	126	40	nm	nm	NOUN
dti-2185	126	41	.	.	PUNCT
dti-2185	127	1	budai	budai	PROPN
dti-2185	127	2	et	et	PROPN
dti-2185	127	3	al	al	PROPN
dti-2185	127	4	evaluated	evaluate	VERB
dti-2185	127	5	the	the	DET
dti-2185	127	6	effects	effect	NOUN
dti-2185	127	7	of	of	ADP
dti-2185	127	8	different	different	ADJ
dti-2185	127	9	opioids	opioid	NOUN
dti-2185	127	10	on	on	ADP
dti-2185	127	11	dppc	dppc	ADJ
dti-2185	127	12	multilamellar	multilamellar	ADJ
dti-2185	127	13	vesicles	vesicle	NOUN
dti-2185	127	14	(	(	PUNCT
dti-2185	127	15	mlvs	mlvs	NUM
dti-2185	127	16	)	)	PUNCT
dti-2185	127	17	by	by	ADP
dti-2185	127	18	dsc	dsc	NOUN
dti-2185	127	19	and	and	CCONJ
dti-2185	127	20	electron	electron	NOUN
dti-2185	127	21	paramagnetic	paramagnetic	ADJ
dti-2185	127	22	resonance	resonance	NOUN
dti-2185	127	23	(	(	PUNCT
dti-2185	127	24	epr	epr	ADJ
dti-2185	127	25	)	)	PUNCT
dti-2185	127	26	spectroscopy	spectroscopy	NOUN
dti-2185	127	27	(	(	PUNCT
dti-2185	127	28	60	60	NUM
dti-2185	127	29	)	)	PUNCT
dti-2185	127	30	.	.	PUNCT
dti-2185	128	1	codeine	codeine	NOUN
dti-2185	128	2	and	and	CCONJ
dti-2185	128	3	n	n	CCONJ
dti-2185	128	4	-	-	PUNCT
dti-2185	128	5	methylcodeine	methylcodeine	NOUN
dti-2185	128	6	reduced	reduce	VERB
dti-2185	128	7	the	the	DET
dti-2185	128	8	phase	phase	NOUN
dti-2185	128	9	transition	transition	NOUN
dti-2185	128	10	temperature	temperature	NOUN
dti-2185	128	11	of	of	ADP
dti-2185	128	12	dppc	dppc	ADJ
dti-2185	128	13	membranes	membrane	NOUN
dti-2185	128	14	at	at	ADP
dti-2185	128	15	0.1	0.1	NUM
dti-2185	128	16	m.	m.	NOUN
dti-2185	128	17	zheng	zheng	PROPN
dti-2185	128	18	et	et	PROPN
dti-2185	128	19	al	al	PROPN
dti-2185	128	20	treated	treat	VERB
dti-2185	128	21	hek	hek	PROPN
dti-2185	128	22	(	(	PUNCT
dti-2185	128	23	human	human	ADJ
dti-2185	128	24	embryonic	embryonic	ADJ
dti-2185	128	25	kidney	kidney	NOUN
dti-2185	128	26	)	)	PUNCT
dti-2185	128	27	293	293	NUM
dti-2185	128	28	cells	cell	NOUN
dti-2185	128	29	expressing	express	VERB
dti-2185	128	30	μ	μ	NOUN
dti-2185	128	31	-	-	NOUN
dti-2185	128	32	receptors	receptor	NOUN
dti-2185	128	33	with	with	ADP
dti-2185	128	34	or	or	CCONJ
dti-2185	128	35	subcutaneously	subcutaneously	ADV
dti-2185	128	36	injected	inject	VERB
dti-2185	128	37	mice	mouse	NOUN
dti-2185	128	38	with	with	ADP
dti-2185	128	39	opioid	opioid	ADJ
dti-2185	128	40	agonists	agonist	NOUN
dti-2185	128	41	(	(	PUNCT
dti-2185	128	42	61	61	NUM
dti-2185	128	43	)	)	PUNCT
dti-2185	128	44	.	.	PUNCT
dti-2185	129	1	sdgc	sdgc	NOUN
dti-2185	129	2	cell	cell	NOUN
dti-2185	129	3	fractions	fraction	NOUN
dti-2185	129	4	and	and	CCONJ
dti-2185	129	5	hippocampus	hippocampus	NOUN
dti-2185	129	6	isolates	isolate	NOUN
dti-2185	129	7	demonstrated	demonstrate	VERB
dti-2185	129	8	that	that	SCONJ
dti-2185	129	9	etorphine	etorphine	NOUN
dti-2185	129	10	of	of	ADP
dti-2185	129	11	10	10	NUM
dti-2185	129	12	nm	nm	NOUN
dti-2185	129	13	and	and	CCONJ
dti-2185	129	14	5	5	NUM
dti-2185	129	15	μg	μg	PROPN
dti-2185	129	16	/	/	SYM
dti-2185	129	17	kg	kg	PROPN
dti-2185	129	18	(	(	PUNCT
dti-2185	129	19	s.c	s.c	PROPN
dti-2185	129	20	.	.	PROPN
dti-2185	129	21	)	)	PUNCT
dti-2185	129	22	translocate	translocate	VERB
dti-2185	129	23	μ	μ	NOUN
dti-2185	129	24	-	-	NOUN
dti-2185	129	25	receptors	receptor	NOUN
dti-2185	129	26	from	from	ADP
dti-2185	129	27	lipid	lipid	ADJ
dti-2185	129	28	rafts	raft	NOUN
dti-2185	129	29	to	to	ADP
dti-2185	129	30	non	non	ADJ
dti-2185	129	31	-	-	ADJ
dti-2185	129	32	raft	raft	ADJ
dti-2185	129	33	regions	region	NOUN
dti-2185	129	34	as	as	ADV
dti-2185	129	35	well	well	ADV
dti-2185	129	36	as	as	ADP
dti-2185	129	37	cholesterol	cholesterol	NOUN
dti-2185	129	38	-	-	PUNCT
dti-2185	129	39	depleting	deplete	VERB
dti-2185	129	40	mbc	mbc	PROPN
dti-2185	129	41	.	.	PUNCT
dti-2185	130	1	anti	anti	ADJ
dti-2185	130	2	-	-	ADJ
dti-2185	130	3	inflammatory	inflammatory	ADJ
dti-2185	130	4	drugs	drug	NOUN
dti-2185	130	5	non	non	ADJ
dti-2185	130	6	-	-	ADJ
dti-2185	130	7	steroidal	steroidal	ADJ
dti-2185	130	8	anti	anti	ADJ
dti-2185	130	9	-	-	ADJ
dti-2185	130	10	inflammatory	inflammatory	ADJ
dti-2185	130	11	drugs	drug	NOUN
dti-2185	130	12	are	be	AUX
dti-2185	130	13	considered	consider	VERB
dti-2185	130	14	to	to	PART
dti-2185	130	15	exert	exert	VERB
dti-2185	130	16	therapeutic	therapeutic	ADJ
dti-2185	130	17	and	and	CCONJ
dti-2185	130	18	adverse	adverse	ADJ
dti-2185	130	19	effects	effect	NOUN
dti-2185	130	20	by	by	ADP
dti-2185	130	21	inhibiting	inhibit	VERB
dti-2185	130	22	cyclooxygenase	cyclooxygenase	NOUN
dti-2185	130	23	(	(	PUNCT
dti-2185	130	24	cox)-2	cox)-2	NOUN
dti-2185	130	25	and	and	CCONJ
dti-2185	130	26	cox-1	cox-1	NOUN
dti-2185	130	27	,	,	PUNCT
dti-2185	130	28	respectively	respectively	ADV
dti-2185	130	29	.	.	PUNCT
dti-2185	130	30	cox-2	cox-2	NOUN
dti-2185	130	31	is	be	AUX
dti-2185	130	32	localized	localize	VERB
dti-2185	130	33	in	in	ADP
dti-2185	130	34	lipid	lipid	NOUN
dti-2185	130	35	raft	raft	NOUN
dti-2185	130	36	/	/	SYM
dti-2185	130	37	caveola	caveola	NOUN
dti-2185	130	38	membrane	membrane	NOUN
dti-2185	130	39	domains	domain	NOUN
dti-2185	130	40	and	and	CCONJ
dti-2185	130	41	associated	associate	VERB
dti-2185	130	42	with	with	ADP
dti-2185	130	43	caveolin-1	caveolin-1	NUM
dti-2185	130	44	(	(	PUNCT
dti-2185	130	45	62	62	NUM
dti-2185	130	46	)	)	PUNCT
dti-2185	130	47	.	.	PUNCT
dti-2185	131	1	alsop	alsop	PROPN
dti-2185	131	2	et	et	PROPN
dti-2185	131	3	al	al	PROPN
dti-2185	131	4	studied	study	VERB
dti-2185	131	5	the	the	DET
dti-2185	131	6	effects	effect	NOUN
dti-2185	131	7	of	of	ADP
dti-2185	131	8	aspirin	aspirin	NOUN
dti-2185	131	9	on	on	ADP
dti-2185	131	10	different	different	ADJ
dti-2185	131	11	dppc	dppc	NOUN
dti-2185	131	12	/	/	SYM
dti-2185	131	13	cholesterol	cholesterol	NOUN
dti-2185	131	14	bilayer	bilayer	NOUN
dti-2185	131	15	membrane	membrane	NOUN
dti-2185	131	16	systems	system	NOUN
dti-2185	131	17	by	by	ADP
dti-2185	131	18	langmuirblodgett	langmuirblodgett	NOUN
dti-2185	131	19	,	,	PUNCT
dti-2185	131	20	dsc	dsc	NOUN
dti-2185	131	21	and	and	CCONJ
dti-2185	131	22	nd	nd	NOUN
dti-2185	131	23	experiments	experiment	NOUN
dti-2185	131	24	(	(	PUNCT
dti-2185	131	25	63	63	NUM
dti-2185	131	26	)	)	PUNCT
dti-2185	131	27	.	.	PUNCT
dti-2185	132	1	aspirin	aspirin	NOUN
dti-2185	132	2	(	(	PUNCT
dti-2185	132	3	3	3	NUM
dti-2185	132	4	mm	mm	NOUN
dti-2185	132	5	)	)	PUNCT
dti-2185	132	6	increased	increase	VERB
dti-2185	132	7	the	the	DET
dti-2185	132	8	membrane	membrane	NOUN
dti-2185	132	9	fluidity	fluidity	NOUN
dti-2185	132	10	of	of	ADP
dti-2185	132	11	dppc	dppc	ADJ
dti-2185	132	12	membranes	membrane	NOUN
dti-2185	132	13	containing	contain	VERB
dti-2185	132	14	32.5	32.5	NUM
dti-2185	132	15	mol%	mol%	PROPN
dti-2185	132	16	cholesterol	cholesterol	NOUN
dti-2185	132	17	,	,	PUNCT
dti-2185	132	18	disrupted	disrupt	VERB
dti-2185	132	19	the	the	DET
dti-2185	132	20	membrane	membrane	NOUN
dti-2185	132	21	organization	organization	NOUN
dti-2185	132	22	and	and	CCONJ
dti-2185	132	23	prevented	prevent	VERB
dti-2185	132	24	the	the	DET
dti-2185	132	25	formation	formation	NOUN
dti-2185	132	26	of	of	ADP
dti-2185	132	27	lo	lo	PROPN
dti-2185	132	28	phase	phase	NOUN
dti-2185	132	29	lipid	lipid	NOUN
dti-2185	132	30	rafts	raft	NOUN
dti-2185	132	31	.	.	PUNCT
dti-2185	133	1	in	in	ADP
dti-2185	133	2	the	the	DET
dti-2185	133	3	following	follow	VERB
dti-2185	133	4	neutron	neutron	NOUN
dti-2185	133	5	scattering	scatter	VERB
dti-2185	133	6	experiments	experiment	NOUN
dti-2185	133	7	and	and	CCONJ
dti-2185	133	8	molecular	molecular	ADJ
dti-2185	133	9	dynamics	dynamic	NOUN
dti-2185	133	10	simulations	simulation	NOUN
dti-2185	133	11	,	,	PUNCT
dti-2185	133	12	they	they	PRON
dti-2185	133	13	prepared	prepare	VERB
dti-2185	133	14	mlvs	mlvs	NOUN
dti-2185	133	15	with	with	ADP
dti-2185	133	16	70	70	NUM
dti-2185	133	17	mol%	mol%	PROPN
dti-2185	133	18	1,2	1,2	NUM
dti-2185	133	19	-	-	PUNCT
dti-2185	133	20	dimyristoylphosphatidylcholine	dimyristoylphosphatidylcholine	NOUN
dti-2185	133	21	(	(	PUNCT
dti-2185	133	22	dmpc	dmpc	NOUN
dti-2185	133	23	)	)	PUNCT
dti-2185	133	24	and	and	CCONJ
dti-2185	133	25	30	30	NUM
dti-2185	133	26	mol%	mol%	PROPN
dti-2185	133	27	cholesterol	cholesterol	NOUN
dti-2185	133	28	to	to	PART
dti-2185	133	29	study	study	VERB
dti-2185	133	30	the	the	DET
dti-2185	133	31	membrane	membrane	NOUN
dti-2185	133	32	effect	effect	NOUN
dti-2185	133	33	of	of	ADP
dti-2185	133	34	aspirin	aspirin	NOUN
dti-2185	133	35	(	(	PUNCT
dti-2185	133	36	64	64	NUM
dti-2185	133	37	)	)	PUNCT
dti-2185	133	38	.	.	PUNCT
dti-2185	134	1	aspirin	aspirin	PROPN
dti-2185	134	2	bound	bind	VERB
dti-2185	134	3	to	to	ADP
dti-2185	134	4	raft	raft	VERB
dti-2185	134	5	-	-	PUNCT
dti-2185	134	6	like	like	ADJ
dti-2185	134	7	lo	lo	NOUN
dti-2185	134	8	phase	phase	NOUN
dti-2185	134	9	domains	domain	NOUN
dti-2185	134	10	and	and	CCONJ
dti-2185	134	11	disrupted	disrupt	VERB
dti-2185	134	12	their	their	PRON
dti-2185	134	13	organization	organization	NOUN
dti-2185	134	14	at	at	ADP
dti-2185	134	15	10	10	NUM
dti-2185	134	16	mol%	mol%	NOUN
dti-2185	134	17	.	.	PUNCT
dti-2185	135	1	zhou	zhou	PROPN
dti-2185	135	2	et	et	PROPN
dti-2185	135	3	al	al	PROPN
dti-2185	135	4	reported	report	VERB
dti-2185	135	5	that	that	SCONJ
dti-2185	135	6	5	5	NUM
dti-2185	135	7	μm	μm	NOUN
dti-2185	135	8	indomethacin	indomethacin	NOUN
dti-2185	135	9	,	,	PUNCT
dti-2185	135	10	25	25	NUM
dti-2185	135	11	μm	μm	NUM
dti-2185	135	12	naproxen	naproxen	NOUN
dti-2185	135	13	,	,	PUNCT
dti-2185	135	14	50	50	NUM
dti-2185	135	15	μm	μm	NOUN
dti-2185	135	16	aspirin	aspirin	NOUN
dti-2185	135	17	and	and	CCONJ
dti-2185	135	18	150	150	NUM
dti-2185	135	19	μm	μm	NOUN
dti-2185	135	20	ibuprofen	ibuprofen	NOUN
dti-2185	135	21	acted	act	VERB
dti-2185	135	22	on	on	ADP
dti-2185	135	23	bhk	bhk	PROPN
dti-2185	135	24	(	(	PUNCT
dti-2185	135	25	baby	baby	NOUN
dti-2185	135	26	hamster	hamster	PROPN
dti-2185	135	27	kidney	kidney	PROPN
dti-2185	135	28	)	)	PUNCT
dti-2185	135	29	cells	cell	NOUN
dti-2185	135	30	to	to	PART
dti-2185	135	31	affect	affect	VERB
dti-2185	135	32	the	the	DET
dti-2185	135	33	organization	organization	NOUN
dti-2185	135	34	of	of	ADP
dti-2185	135	35	raft	raft	NOUN
dti-2185	135	36	-	-	PUNCT
dti-2185	135	37	like	like	ADJ
dti-2185	135	38	ordered	order	VERB
dti-2185	135	39	lipid	lipid	NOUN
dti-2185	135	40	and	and	CCONJ
dti-2185	135	41	protein	protein	NOUN
dti-2185	135	42	membrane	membrane	NOUN
dti-2185	135	43	nanoclusters	nanocluster	NOUN
dti-2185	135	44	by	by	ADP
dti-2185	135	45	interacting	interact	VERB
dti-2185	135	46	with	with	ADP
dti-2185	135	47	plasma	plasma	NOUN
dti-2185	135	48	membranes	membrane	NOUN
dti-2185	135	49	(	(	PUNCT
dti-2185	135	50	65	65	NUM
dti-2185	135	51	)	)	PUNCT
dti-2185	135	52	.	.	PUNCT
dti-2185	136	1	anticancer	anticancer	NOUN
dti-2185	136	2	drugs	drug	NOUN
dti-2185	136	3	in	in	ADP
dti-2185	136	4	addition	addition	NOUN
dti-2185	136	5	to	to	ADP
dti-2185	136	6	conventional	conventional	ADJ
dti-2185	136	7	mechanistic	mechanistic	ADJ
dti-2185	136	8	effects	effect	NOUN
dti-2185	136	9	,	,	PUNCT
dti-2185	136	10	anticancer	anticancer	NOUN
dti-2185	136	11	drugs	drug	NOUN
dti-2185	136	12	exhibit	exhibit	VERB
dti-2185	136	13	apoptosis	apoptosis	NOUN
dti-2185	136	14	-	-	PUNCT
dti-2185	136	15	inducing	induce	VERB
dti-2185	136	16	activity	activity	NOUN
dti-2185	136	17	.	.	PUNCT
dti-2185	137	1	lipid	lipid	NOUN
dti-2185	137	2	rafts	raft	NOUN
dti-2185	137	3	contribute	contribute	VERB
dti-2185	137	4	to	to	ADP
dti-2185	137	5	induction	induction	NOUN
dti-2185	137	6	of	of	ADP
dti-2185	137	7	the	the	DET
dti-2185	137	8	apoptosis	apoptosis	NOUN
dti-2185	137	9	selective	selective	NOUN
dti-2185	137	10	for	for	ADP
dti-2185	137	11	cancer	cancer	NOUN
dti-2185	137	12	cells	cell	NOUN
dti-2185	137	13	(	(	PUNCT
dti-2185	137	14	66	66	NUM
dti-2185	137	15	)	)	PUNCT
dti-2185	137	16	.	.	PUNCT
dti-2185	138	1	alkylphospholipids	alkylphospholipid	NOUN
dti-2185	138	2	,	,	PUNCT
dti-2185	138	3	platinum(ii	platinum(ii	ADJ
dti-2185	138	4	)	)	PUNCT
dti-2185	138	5	complex	complex	NOUN
dti-2185	138	6	and	and	CCONJ
dti-2185	138	7	antibiotics	antibiotic	NOUN
dti-2185	138	8	are	be	AUX
dti-2185	138	9	presumed	presume	VERB
dti-2185	138	10	to	to	PART
dti-2185	138	11	act	act	VERB
dti-2185	138	12	on	on	ADP
dti-2185	138	13	lipid	lipid	ADJ
dti-2185	138	14	rafts	raft	NOUN
dti-2185	138	15	as	as	ADP
dti-2185	138	16	a	a	DET
dti-2185	138	17	membrane	membrane	NOUN
dti-2185	138	18	gateway	gateway	NOUN
dti-2185	138	19	to	to	PART
dti-2185	138	20	induce	induce	VERB
dti-2185	138	21	apoptosis	apoptosis	NOUN
dti-2185	138	22	(	(	PUNCT
dti-2185	138	23	67	67	NUM
dti-2185	138	24	)	)	PUNCT
dti-2185	138	25	.	.	PUNCT
dti-2185	139	1	alves	alves	PROPN
dti-2185	139	2	et	et	PROPN
dti-2185	139	3	al	al	PROPN
dti-2185	139	4	recently	recently	ADV
dti-2185	139	5	published	publish	VERB
dti-2185	139	6	an	an	DET
dti-2185	139	7	excellent	excellent	ADJ
dti-2185	139	8	review	review	NOUN
dti-2185	139	9	on	on	ADP
dti-2185	139	10	the	the	DET
dti-2185	139	11	biophysics	biophysic	NOUN
dti-2185	139	12	of	of	ADP
dti-2185	139	13	cancer	cancer	NOUN
dti-2185	139	14	cells	cell	NOUN
dti-2185	139	15	and	and	CCONJ
dti-2185	139	16	the	the	DET
dti-2185	139	17	relevance	relevance	NOUN
dti-2185	139	18	of	of	ADP
dti-2185	139	19	drug	drug	NOUN
dti-2185	139	20	and	and	CCONJ
dti-2185	139	21	membrane	membrane	NOUN
dti-2185	139	22	interaction	interaction	NOUN
dti-2185	139	23	to	to	ADP
dti-2185	139	24	cancer	cancer	NOUN
dti-2185	139	25	therapy	therapy	NOUN
dti-2185	139	26	(	(	PUNCT
dti-2185	139	27	68	68	NUM
dti-2185	139	28	)	)	PUNCT
dti-2185	139	29	.	.	PUNCT
dti-2185	140	1	results	result	NOUN
dti-2185	140	2	of	of	ADP
dti-2185	140	3	the	the	DET
dti-2185	140	4	literature	literature	NOUN
dti-2185	140	5	search	search	NOUN
dti-2185	140	6	on	on	ADP
dti-2185	140	7	the	the	DET
dti-2185	140	8	interaction	interaction	NOUN
dti-2185	140	9	of	of	ADP
dti-2185	140	10	anticancer	anticancer	NOUN
dti-2185	140	11	drugs	drug	NOUN
dti-2185	140	12	with	with	ADP
dti-2185	140	13	membrane	membrane	NOUN
dti-2185	140	14	lipid	lipid	NOUN
dti-2185	140	15	rafts	raft	NOUN
dti-2185	140	16	and	and	CCONJ
dti-2185	140	17	membranes	membrane	NOUN
dti-2185	140	18	are	be	AUX
dti-2185	140	19	shown	show	VERB
dti-2185	140	20	in	in	ADP
dti-2185	140	21	table	table	NOUN
dti-2185	140	22	iv	iv	NOUN
dti-2185	140	23	.	.	PUNCT
dti-2185	140	24	alkylphospholipids	alkylphospholipids	PROPN
dti-2185	140	25	ausili	ausili	PROPN
dti-2185	140	26	et	et	PROPN
dti-2185	140	27	al	al	PROPN
dti-2185	140	28	treated	treat	VERB
dti-2185	140	29	mlvs	mlvs	ADV
dti-2185	140	30	prepared	prepare	VERB
dti-2185	140	31	with	with	ADP
dti-2185	140	32	popc	popc	NOUN
dti-2185	140	33	,	,	PUNCT
dti-2185	140	34	sm	sm	PROPN
dti-2185	140	35	and	and	CCONJ
dti-2185	140	36	cholesterol	cholesterol	NOUN
dti-2185	140	37	(	(	PUNCT
dti-2185	140	38	1:1:1	1:1:1	PROPN
dti-2185	140	39	molar	molar	ADJ
dti-2185	140	40	ratio	ratio	NOUN
dti-2185	140	41	)	)	PUNCT
dti-2185	140	42	with	with	ADP
dti-2185	140	43	edelfosine	edelfosine	NOUN
dti-2185	140	44	at	at	ADP
dti-2185	140	45	10	10	NUM
dti-2185	140	46	-	-	SYM
dti-2185	140	47	20	20	NUM
dti-2185	140	48	mol%	mol%	PROPN
dti-2185	140	49	relative	relative	ADJ
dti-2185	140	50	to	to	ADP
dti-2185	140	51	membrane	membrane	NOUN
dti-2185	140	52	lipids	lipid	NOUN
dti-2185	140	53	,	,	PUNCT
dti-2185	140	54	followed	follow	VERB
dti-2185	140	55	by	by	ADP
dti-2185	140	56	dsc	dsc	NOUN
dti-2185	140	57	,	,	PUNCT
dti-2185	140	58	xd	xd	NOUN
dti-2185	140	59	and	and	CCONJ
dti-2185	140	60	nmr	nmr	NOUN
dti-2185	140	61	analysis	analysis	NOUN
dti-2185	140	62	(	(	PUNCT
dti-2185	140	63	69	69	NUM
dti-2185	140	64	)	)	PUNCT
dti-2185	140	65	.	.	PUNCT
dti-2185	141	1	edelfosine	edelfosine	PROPN
dti-2185	141	2	altered	alter	VERB
dti-2185	141	3	the	the	DET
dti-2185	141	4	raft	raft	NOUN
dti-2185	141	5	organization	organization	NOUN
dti-2185	141	6	and	and	CCONJ
dti-2185	141	7	induced	induce	VERB
dti-2185	141	8	the	the	DET
dti-2185	141	9	appearance	appearance	NOUN
dti-2185	141	10	of	of	ADP
dti-2185	141	11	a	a	DET
dti-2185	141	12	sharp	sharp	ADJ
dti-2185	141	13	phase	phase	NOUN
dti-2185	141	14	transition	transition	NOUN
dti-2185	141	15	at	at	ADP
dti-2185	141	16	20	20	NUM
dti-2185	141	17	mol%	mol%	NOUN
dti-2185	141	18	,	,	PUNCT
dti-2185	141	19	suggesting	suggest	VERB
dti-2185	141	20	a	a	DET
dti-2185	141	21	fluidity	fluidity	NOUN
dti-2185	141	22	increase	increase	NOUN
dti-2185	141	23	in	in	ADP
dti-2185	141	24	membrane	membrane	NOUN
dti-2185	141	25	lipid	lipid	NOUN
dti-2185	141	26	rafts	raft	NOUN
dti-2185	141	27	.	.	PUNCT
dti-2185	142	1	when	when	SCONJ
dti-2185	142	2	incubating	incubate	VERB
dti-2185	142	3	with	with	ADP
dti-2185	142	4	human	human	ADJ
dti-2185	142	5	acute	acute	PROPN
dti-2185	142	6	t	t	PROPN
dti-2185	142	7	-	-	PUNCT
dti-2185	142	8	cell	cell	NOUN
dti-2185	142	9	leukemia	leukemia	NOUN
dti-2185	142	10	(	(	PUNCT
dti-2185	142	11	jurkat	jurkat	PROPN
dti-2185	142	12	t	t	PROPN
dti-2185	142	13	)	)	PUNCT
dti-2185	142	14	cells	cell	NOUN
dti-2185	142	15	,	,	PUNCT
dti-2185	142	16	edelfosine	edelfosine	NOUN
dti-2185	142	17	colocalized	colocalize	VERB
dti-2185	142	18	in	in	ADP
dti-2185	142	19	lipid	lipid	ADJ
dti-2185	142	20	rafts	raft	NOUN
dti-2185	142	21	at	at	ADP
dti-2185	142	22	concentrations	concentration	NOUN
dti-2185	142	23	higher	high	ADJ
dti-2185	142	24	than	than	ADP
dti-2185	142	25	20	20	NUM
dti-2185	142	26	mol%	mol%	NOUN
dti-2185	142	27	.	.	PUNCT
dti-2185	143	1	10-(octyloxy	10-(octyloxy	NUM
dti-2185	143	2	)	)	PUNCT
dti-2185	143	3	decyl-2-(trimethylammonium	decyl-2-(trimethylammonium	NOUN
dti-2185	143	4	)	)	PUNCT
dti-2185	143	5	ethyl	ethyl	PROPN
dti-2185	143	6	phosphate	phosphate	NOUN
dti-2185	143	7	(	(	PUNCT
dti-2185	143	8	odpc	odpc	ADV
dti-2185	143	9	)	)	PUNCT
dti-2185	143	10	with	with	ADP
dti-2185	143	11	the	the	DET
dti-2185	143	12	cytotoxic	cytotoxic	ADJ
dti-2185	143	13	activity	activity	NOUN
dti-2185	143	14	against	against	ADP
dti-2185	143	15	cancer	cancer	NOUN
dti-2185	143	16	cell	cell	NOUN
dti-2185	143	17	lines	line	NOUN
dti-2185	143	18	inhibits	inhibit	VERB
dti-2185	143	19	the	the	DET
dti-2185	143	20	proliferation	proliferation	NOUN
dti-2185	143	21	of	of	ADP
dti-2185	143	22	leukemia	leukemia	NOUN
dti-2185	143	23	cells	cell	NOUN
dti-2185	143	24	by	by	ADP
dti-2185	143	25	inducing	induce	VERB
dti-2185	143	26	apoptosis	apoptosis	NOUN
dti-2185	143	27	.	.	PUNCT
dti-2185	144	1	gomide	gomide	NOUN
dti-2185	144	2	et	et	PROPN
dti-2185	144	3	al	al	PROPN
dti-2185	144	4	prepared	prepare	VERB
dti-2185	144	5	giant	giant	ADJ
dti-2185	144	6	unilamellar	unilamellar	ADJ
dti-2185	144	7	vesicles	vesicle	NOUN
dti-2185	144	8	(	(	PUNCT
dti-2185	144	9	guvs	guvs	X
dti-2185	144	10	)	)	PUNCT
dti-2185	144	11	with	with	ADP
dti-2185	144	12	dopc	dopc	NOUN
dti-2185	144	13	,	,	PUNCT
dti-2185	144	14	sm	sm	PROPN
dti-2185	144	15	and	and	CCONJ
dti-2185	144	16	cholesterol	cholesterol	NOUN
dti-2185	144	17	(	(	PUNCT
dti-2185	144	18	1:1:1	1:1:1	PROPN
dti-2185	144	19	molar	molar	ADJ
dti-2185	144	20	ratio	ratio	NOUN
dti-2185	144	21	)	)	PUNCT
dti-2185	144	22	to	to	PART
dti-2185	144	23	examine	examine	VERB
dti-2185	144	24	the	the	DET
dti-2185	144	25	effects	effect	NOUN
dti-2185	144	26	of	of	ADP
dti-2185	144	27	perifosine	perifosine	NOUN
dti-2185	144	28	and	and	CCONJ
dti-2185	144	29	odpc	odpc	ADV
dti-2185	144	30	on	on	ADP
dti-2185	144	31	lipid	lipid	ADJ
dti-2185	144	32	rafts	raft	NOUN
dti-2185	144	33	(	(	PUNCT
dti-2185	144	34	70	70	NUM
dti-2185	144	35	)	)	PUNCT
dti-2185	144	36	.	.	PUNCT
dti-2185	145	1	in	in	ADP
dti-2185	145	2	fluorescence	fluorescence	PROPN
dti-2185	145	3	microscopic	microscopic	PROPN
dti-2185	145	4	observations	observation	NOUN
dti-2185	145	5	,	,	PUNCT
dti-2185	145	6	perifosine	perifosine	NOUN
dti-2185	145	7	and	and	CCONJ
dti-2185	145	8	odpc	odpc	ADV
dti-2185	145	9	disrupted	disrupt	VERB
dti-2185	145	10	membrane	membrane	NOUN
dti-2185	145	11	raft	raft	NOUN
dti-2185	145	12	domains	domain	NOUN
dti-2185	145	13	in	in	ADP
dti-2185	145	14	guvs	guvs	NOUN
dti-2185	145	15	so	so	SCONJ
dti-2185	145	16	that	that	SCONJ
dti-2185	145	17	the	the	DET
dti-2185	145	18	domains	domain	NOUN
dti-2185	145	19	disappeared	disappear	VERB
dti-2185	145	20	in	in	ADP
dti-2185	145	21	less	less	ADJ
dti-2185	145	22	than	than	ADP
dti-2185	145	23	1	1	NUM
dti-2185	145	24	min	min	NOUN
dti-2185	145	25	after	after	ADP
dti-2185	145	26	treatment	treatment	NOUN
dti-2185	145	27	at	at	ADP
dti-2185	145	28	100	100	NUM
dti-2185	145	29	μm	μm	NOUN
dti-2185	145	30	.	.	PUNCT
dti-2185	146	1	castro	castro	PROPN
dti-2185	146	2	et	et	PROPN
dti-2185	146	3	al	al	PROPN
dti-2185	146	4	treated	treat	VERB
dti-2185	146	5	mlvs	mlvs	ADV
dti-2185	146	6	or	or	CCONJ
dti-2185	146	7	unilamellar	unilamellar	ADJ
dti-2185	146	8	vesicles	vesicle	NOUN
dti-2185	146	9	(	(	PUNCT
dti-2185	146	10	ulvs	ulvs	NOUN
dti-2185	146	11	)	)	PUNCT
dti-2185	146	12	prepared	prepare	VERB
dti-2185	146	13	with	with	ADP
dti-2185	146	14	popc	popc	NOUN
dti-2185	146	15	,	,	PUNCT
dti-2185	146	16	n	n	CCONJ
dti-2185	146	17	-	-	PUNCT
dti-2185	146	18	palmitoyl	palmitoyl	NOUN
dti-2185	146	19	-	-	PUNCT
dti-2185	146	20	sm	sm	NOUN
dti-2185	146	21	and	and	CCONJ
dti-2185	146	22	cholesterol	cholesterol	NOUN
dti-2185	146	23	(	(	PUNCT
dti-2185	146	24	1:1:1	1:1:1	PROPN
dti-2185	146	25	molar	molar	ADJ
dti-2185	146	26	ratio	ratio	NOUN
dti-2185	146	27	)	)	PUNCT
dti-2185	146	28	with	with	ADP
dti-2185	146	29	anticancer	anticancer	NOUN
dti-2185	146	30	alkylphospholipids	alkylphospholipid	NOUN
dti-2185	146	31	,	,	PUNCT
dti-2185	146	32	followed	follow	VERB
dti-2185	146	33	by	by	ADP
dti-2185	146	34	fa	fa	NOUN
dti-2185	146	35	measurements	measurement	NOUN
dti-2185	146	36	(	(	PUNCT
dti-2185	146	37	71	71	NUM
dti-2185	146	38	)	)	PUNCT
dti-2185	146	39	.	.	PUNCT
dti-2185	147	1	edelfosine	edelfosine	NOUN
dti-2185	147	2	and	and	CCONJ
dti-2185	147	3	miltefosine	miltefosine	NOUN
dti-2185	147	4	were	be	AUX
dti-2185	147	5	demonstrated	demonstrate	VERB
dti-2185	147	6	to	to	PART
dti-2185	147	7	increase	increase	VERB
dti-2185	147	8	the	the	DET
dti-2185	147	9	fluidity	fluidity	NOUN
dti-2185	147	10	of	of	ADP
dti-2185	147	11	raft	raft	NOUN
dti-2185	147	12	model	model	NOUN
dti-2185	147	13	membranes	membrane	NOUN
dti-2185	147	14	at	at	ADP
dti-2185	147	15	5	5	NUM
dti-2185	147	16	-	-	SYM
dti-2185	147	17	10	10	NUM
dti-2185	147	18	mol%	mol%	PROPN
dti-2185	147	19	relative	relative	ADJ
dti-2185	147	20	to	to	ADP
dti-2185	147	21	membrane	membrane	NOUN
dti-2185	147	22	lipids	lipid	NOUN
dti-2185	147	23	.	.	PUNCT
dti-2185	148	1	wnętrzak	wnętrzak	PROPN
dti-2185	148	2	et	et	PROPN
dti-2185	148	3	al	al	PROPN
dti-2185	148	4	studied	study	VERB
dti-2185	148	5	the	the	DET
dti-2185	148	6	effects	effect	NOUN
dti-2185	148	7	of	of	ADP
dti-2185	148	8	synthetic	synthetic	ADJ
dti-2185	148	9	phospholipid	phospholipid	NOUN
dti-2185	148	10	analog	analog	NOUN
dti-2185	148	11	erucylphosphocholine	erucylphosphocholine	ADJ
dti-2185	148	12	on	on	ADP
dti-2185	148	13	raft	raft	NOUN
dti-2185	148	14	-	-	PUNCT
dti-2185	148	15	mimic	mimic	ADJ
dti-2185	148	16	langmuir	langmuir	NOUN
dti-2185	148	17	monolayers	monolayer	NOUN
dti-2185	148	18	composed	compose	VERB
dti-2185	148	19	of	of	ADP
dti-2185	148	20	sm	sm	NOUN
dti-2185	148	21	and	and	CCONJ
dti-2185	148	22	cholesterol	cholesterol	NOUN
dti-2185	148	23	(	(	PUNCT
dti-2185	148	24	2:1	2:1	NUM
dti-2185	148	25	molar	molar	ADJ
dti-2185	148	26	ratio	ratio	NOUN
dti-2185	148	27	)	)	PUNCT
dti-2185	148	28	(	(	PUNCT
dti-2185	148	29	72	72	NUM
dti-2185	148	30	)	)	PUNCT
dti-2185	148	31	.	.	PUNCT
dti-2185	149	1	erucylphosphocholine	erucylphosphocholine	PROPN
dti-2185	149	2	increased	increase	VERB
dti-2185	149	3	the	the	DET
dti-2185	149	4	membrane	membrane	NOUN
dti-2185	149	5	raft	raft	NOUN
dti-2185	149	6	fluidity	fluidity	NOUN
dti-2185	149	7	at	at	ADP
dti-2185	149	8	higher	high	ADJ
dti-2185	149	9	than	than	ADP
dti-2185	149	10	0.3	0.3	NUM
dti-2185	149	11	mol%	mol%	PROPN
dti-2185	149	12	relative	relative	ADJ
dti-2185	149	13	to	to	ADP
dti-2185	149	14	membrane	membrane	NOUN
dti-2185	149	15	lipids	lipid	NOUN
dti-2185	149	16	and	and	CCONJ
dti-2185	149	17	weakened	weaken	VERB
dti-2185	149	18	the	the	DET
dti-2185	149	19	interaction	interaction	NOUN
dti-2185	149	20	between	between	ADP
dti-2185	149	21	cholesterol	cholesterol	NOUN
dti-2185	149	22	and	and	CCONJ
dti-2185	149	23	sm	sm	NOUN
dti-2185	149	24	.	.	PUNCT
dti-2185	150	1	in	in	ADP
dti-2185	150	2	a	a	DET
dti-2185	150	3	thermodynamic	thermodynamic	ADJ
dti-2185	150	4	study	study	NOUN
dti-2185	150	5	using	use	VERB
dti-2185	150	6	the	the	DET
dti-2185	150	7	same	same	ADJ
dti-2185	150	8	langmuir	langmuir	PROPN
dti-2185	150	9	monolayers	monolayer	NOUN
dti-2185	150	10	,	,	PUNCT
dti-2185	150	11	anticancer	anticancer	NOUN
dti-2185	150	12	2	2	NUM
dti-2185	150	13	-	-	PUNCT
dti-2185	150	14	hydroxyoleic	hydroxyoleic	NOUN
dti-2185	150	15	acid	acid	NOUN
dti-2185	150	16	increased	increase	VERB
dti-2185	150	17	the	the	DET
dti-2185	150	18	membrane	membrane	NOUN
dti-2185	150	19	fluidity	fluidity	NOUN
dti-2185	150	20	of	of	ADP
dti-2185	150	21	raft	raft	NOUN
dti-2185	150	22	-	-	PUNCT
dti-2185	150	23	mimic	mimic	ADJ
dti-2185	150	24	monolayers	monolayer	NOUN
dti-2185	150	25	at	at	ADP
dti-2185	150	26	higher	high	ADJ
dti-2185	150	27	than	than	ADP
dti-2185	150	28	0.1	0.1	NUM
dti-2185	150	29	mol%	mol%	PROPN
dti-2185	150	30	relative	relative	ADJ
dti-2185	150	31	to	to	ADP
dti-2185	150	32	membrane	membrane	NOUN
dti-2185	150	33	lipids	lipid	NOUN
dti-2185	150	34	(	(	PUNCT
dti-2185	150	35	73	73	NUM
dti-2185	150	36	)	)	PUNCT
dti-2185	150	37	.	.	PUNCT
dti-2185	151	1	cisplatin	cisplatin	NOUN
dti-2185	151	2	cisplatin	cisplatin	NOUN
dti-2185	151	3	acts	act	NOUN
dti-2185	151	4	on	on	ADP
dti-2185	151	5	plasma	plasma	NOUN
dti-2185	151	6	membranes	membrane	NOUN
dti-2185	151	7	to	to	PART
dti-2185	151	8	trigger	trigger	VERB
dti-2185	151	9	the	the	DET
dti-2185	151	10	fas	fas	PROPN
dti-2185	151	11	death	death	NOUN
dti-2185	151	12	receptor	receptor	NOUN
dti-2185	151	13	pathway	pathway	NOUN
dti-2185	151	14	at	at	ADP
dti-2185	151	15	a	a	DET
dti-2185	151	16	membrane	membrane	NOUN
dti-2185	151	17	level	level	NOUN
dti-2185	151	18	(	(	PUNCT
dti-2185	151	19	74	74	NUM
dti-2185	151	20	)	)	PUNCT
dti-2185	151	21	.	.	PUNCT
dti-2185	152	1	lacour	lacour	PROPN
dti-2185	152	2	et	et	PROPN
dti-2185	152	3	al	al	PROPN
dti-2185	152	4	treated	treat	VERB
dti-2185	152	5	human	human	ADJ
dti-2185	152	6	colon	colon	NOUN
dti-2185	152	7	carcinoma	carcinoma	NOUN
dti-2185	152	8	(	(	PUNCT
dti-2185	152	9	ht29	ht29	PROPN
dti-2185	152	10	)	)	PUNCT
dti-2185	152	11	cells	cell	NOUN
dti-2185	152	12	(	(	PUNCT
dti-2185	152	13	7	7	NUM
dti-2185	152	14	×	×	NOUN
dti-2185	152	15	105	105	NUM
dti-2185	152	16	cells	cell	NOUN
dti-2185	152	17	)	)	PUNCT
dti-2185	152	18	with	with	ADP
dti-2185	152	19	cisplatin	cisplatin	NOUN
dti-2185	152	20	at	at	ADP
dti-2185	152	21	5	5	NUM
dti-2185	152	22	μg	μg	NOUN
dti-2185	152	23	/	/	SYM
dti-2185	152	24	ml	ml	X
dti-2185	152	25	for	for	ADP
dti-2185	152	26	0.25	0.25	NUM
dti-2185	152	27	-	-	SYM
dti-2185	152	28	4	4	NUM
dti-2185	152	29	hours	hour	NOUN
dti-2185	152	30	(	(	PUNCT
dti-2185	152	31	75	75	NUM
dti-2185	152	32	)	)	PUNCT
dti-2185	152	33	.	.	PUNCT
dti-2185	153	1	the	the	DET
dti-2185	153	2	cells	cell	NOUN
dti-2185	153	3	were	be	AUX
dti-2185	153	4	subjected	subject	VERB
dti-2185	153	5	to	to	ADP
dti-2185	153	6	12	12	NUM
dti-2185	153	7	-	-	PUNCT
dti-2185	153	8	dsa	dsa	NOUN
dti-2185	153	9	(	(	PUNCT
dti-2185	153	10	12	12	NUM
dti-2185	153	11	-	-	PUNCT
dti-2185	153	12	doxylstearic	doxylstearic	ADJ
dti-2185	153	13	acid	acid	NOUN
dti-2185	153	14	)	)	PUNCT
dti-2185	153	15	spin	spin	NOUN
dti-2185	153	16	labeling	labeling	NOUN
dti-2185	153	17	followed	follow	VERB
dti-2185	153	18	by	by	ADP
dti-2185	153	19	epr	epr	PROPN
dti-2185	153	20	spectroscopic	spectroscopic	ADJ
dti-2185	153	21	analysis	analysis	NOUN
dti-2185	153	22	or	or	CCONJ
dti-2185	153	23	cell	cell	NOUN
dti-2185	153	24	lysis	lysis	NOUN
dti-2185	153	25	with	with	ADP
dti-2185	153	26	triton	triton	PROPN
dti-2185	153	27	x-100	x-100	PROPN
dti-2185	153	28	followed	follow	VERB
dti-2185	153	29	by	by	ADP
dti-2185	153	30	sdgc	sdgc	NOUN
dti-2185	153	31	fractionation	fractionation	NOUN
dti-2185	153	32	and	and	CCONJ
dti-2185	153	33	immunoblot	immunoblot	NOUN
dti-2185	153	34	tsuchiya	tsuchiya	PROPN
dti-2185	153	35	and	and	CCONJ
dti-2185	153	36	mizogami	mizogami	PROPN
dti-2185	153	37	41	41	NUM
dti-2185	154	1	©	©	PROPN
dti-2185	154	2	2020	2020	NUM
dti-2185	154	3	the	the	DET
dti-2185	154	4	authors	author	NOUN
dti-2185	154	5	.	.	PUNCT
dti-2185	155	1	published	publish	VERB
dti-2185	155	2	by	by	ADP
dti-2185	155	3	aboutscience	aboutscience	NOUN
dti-2185	155	4	table	table	NOUN
dti-2185	155	5	iv	iv	NUM
dti-2185	155	6	interaction	interaction	NOUN
dti-2185	155	7	of	of	ADP
dti-2185	155	8	anticancer	anticancer	NOUN
dti-2185	155	9	drugs	drug	NOUN
dti-2185	155	10	with	with	ADP
dti-2185	155	11	lipid	lipid	NOUN
dti-2185	155	12	raft	raft	NOUN
dti-2185	155	13	membrane	membrane	NOUN
dti-2185	155	14	domains	domain	NOUN
dti-2185	155	15	and	and	CCONJ
dti-2185	155	16	membranes	membrane	NOUN
dti-2185	155	17	drug	drug	NOUN
dti-2185	155	18	class	class	NOUN
dti-2185	155	19	drug	drug	NOUN
dti-2185	155	20	membrane	membrane	NOUN
dti-2185	155	21	induced	induce	VERB
dti-2185	155	22	membrane	membrane	NOUN
dti-2185	155	23	modification	modification	NOUN
dti-2185	155	24	reference	reference	NOUN
dti-2185	155	25	alkylphospholipid	alkylphospholipid	NOUN
dti-2185	155	26	edelfosine	edelfosine	NOUN
dti-2185	155	27	(	(	PUNCT
dti-2185	155	28	≥20	≥20	NOUN
dti-2185	155	29	mol%	mol%	NOUN
dti-2185	155	30	)	)	PUNCT
dti-2185	155	31	mlvs	mlvs	NOUN
dti-2185	155	32	(	(	PUNCT
dti-2185	155	33	popc	popc	VERB
dti-2185	155	34	,	,	PUNCT
dti-2185	155	35	sm	sm	PROPN
dti-2185	155	36	and	and	CCONJ
dti-2185	155	37	cholesterol	cholesterol	PROPN
dti-2185	155	38	,	,	PUNCT
dti-2185	155	39	1:1:1	1:1:1	NUM
dti-2185	155	40	,	,	PUNCT
dti-2185	155	41	molar	molar	ADJ
dti-2185	155	42	ratio	ratio	NOUN
dti-2185	155	43	)	)	PUNCT
dti-2185	155	44	human	human	ADJ
dti-2185	155	45	acute	acute	NOUN
dti-2185	155	46	t	t	PROPN
dti-2185	155	47	-	-	PUNCT
dti-2185	155	48	cell	cell	NOUN
dti-2185	155	49	leukemia	leukemia	NOUN
dti-2185	155	50	cells	cell	NOUN
dti-2185	155	51	increased	increase	VERB
dti-2185	155	52	the	the	DET
dti-2185	155	53	fluidity	fluidity	NOUN
dti-2185	155	54	of	of	ADP
dti-2185	155	55	lipid	lipid	ADJ
dti-2185	155	56	rafts	raft	NOUN
dti-2185	155	57	colocalized	colocalize	VERB
dti-2185	155	58	in	in	ADP
dti-2185	155	59	membrane	membrane	NOUN
dti-2185	155	60	lipid	lipid	NOUN
dti-2185	155	61	rafts	raft	VERB
dti-2185	155	62	69	69	NUM
dti-2185	155	63	alkylphospholipid	alkylphospholipid	NOUN
dti-2185	155	64	perifosine	perifosine	NOUN
dti-2185	155	65	(	(	PUNCT
dti-2185	155	66	100	100	NUM
dti-2185	155	67	μm	μm	NUM
dti-2185	155	68	)	)	PUNCT
dti-2185	155	69	odpc	odpc	ADV
dti-2185	155	70	(	(	PUNCT
dti-2185	155	71	100	100	NUM
dti-2185	155	72	μm	μm	NOUN
dti-2185	155	73	)	)	PUNCT
dti-2185	155	74	guvs	guvs	NOUN
dti-2185	155	75	(	(	PUNCT
dti-2185	155	76	dopc	dopc	NOUN
dti-2185	155	77	,	,	PUNCT
dti-2185	155	78	sm	sm	PROPN
dti-2185	155	79	and	and	CCONJ
dti-2185	155	80	cholesterol	cholesterol	PROPN
dti-2185	155	81	,	,	PUNCT
dti-2185	155	82	1:1:1	1:1:1	PROPN
dti-2185	155	83	molar	molar	ADJ
dti-2185	155	84	ratio	ratio	NOUN
dti-2185	155	85	)	)	PUNCT
dti-2185	155	86	disrupted	disrupt	VERB
dti-2185	155	87	membrane	membrane	NOUN
dti-2185	155	88	raft	raft	NOUN
dti-2185	155	89	domains	domain	NOUN
dti-2185	155	90	70	70	NUM
dti-2185	155	91	alkylphospholipid	alkylphospholipid	NOUN
dti-2185	155	92	edelfosine	edelfosine	NOUN
dti-2185	155	93	(	(	PUNCT
dti-2185	155	94	5	5	NUM
dti-2185	155	95	-	-	SYM
dti-2185	155	96	10	10	NUM
dti-2185	155	97	mol%	mol%	NOUN
dti-2185	155	98	)	)	PUNCT
dti-2185	155	99	miltefosine	miltefosine	NOUN
dti-2185	155	100	(	(	PUNCT
dti-2185	155	101	5	5	NUM
dti-2185	155	102	-	-	SYM
dti-2185	155	103	10	10	NUM
dti-2185	155	104	mol%	mol%	NOUN
dti-2185	155	105	)	)	PUNCT
dti-2185	155	106	mlvs	mlvs	NOUN
dti-2185	155	107	or	or	CCONJ
dti-2185	155	108	ulvs	ulvs	NOUN
dti-2185	155	109	(	(	PUNCT
dti-2185	155	110	popc	popc	NOUN
dti-2185	155	111	,	,	PUNCT
dti-2185	155	112	n	n	CCONJ
dti-2185	155	113	-	-	PUNCT
dti-2185	155	114	palmitoyl	palmitoyl	NOUN
dti-2185	155	115	-	-	PUNCT
dti-2185	155	116	sm	sm	NOUN
dti-2185	155	117	and	and	CCONJ
dti-2185	155	118	cholesterol	cholesterol	NOUN
dti-2185	155	119	,	,	PUNCT
dti-2185	155	120	1:1:1	1:1:1	PROPN
dti-2185	155	121	molar	molar	ADJ
dti-2185	155	122	ratio	ratio	NOUN
dti-2185	155	123	)	)	PUNCT
dti-2185	155	124	increased	increase	VERB
dti-2185	155	125	the	the	DET
dti-2185	155	126	fluidity	fluidity	NOUN
dti-2185	155	127	of	of	ADP
dti-2185	155	128	raft	raft	NOUN
dti-2185	155	129	model	model	NOUN
dti-2185	155	130	membranes	membrane	NOUN
dti-2185	155	131	71	71	NUM
dti-2185	155	132	alkylphospholipid	alkylphospholipid	NOUN
dti-2185	155	133	erucylphosphocholine	erucylphosphocholine	ADJ
dti-2185	155	134	(	(	PUNCT
dti-2185	155	135	≥0.3	≥0.3	PROPN
dti-2185	155	136	mol%	mol%	NOUN
dti-2185	155	137	)	)	PUNCT
dti-2185	155	138	raft	raft	NOUN
dti-2185	155	139	-	-	PUNCT
dti-2185	155	140	mimic	mimic	ADJ
dti-2185	155	141	langmuir	langmuir	NOUN
dti-2185	155	142	monolayers	monolayer	NOUN
dti-2185	155	143	(	(	PUNCT
dti-2185	155	144	sm	sm	NOUN
dti-2185	155	145	and	and	CCONJ
dti-2185	155	146	cholesterol	cholesterol	PROPN
dti-2185	155	147	,	,	PUNCT
dti-2185	155	148	2:1	2:1	NUM
dti-2185	155	149	molar	molar	ADJ
dti-2185	155	150	ratio	ratio	NOUN
dti-2185	155	151	)	)	PUNCT
dti-2185	155	152	increased	increase	VERB
dti-2185	155	153	the	the	DET
dti-2185	155	154	membrane	membrane	NOUN
dti-2185	155	155	raft	raft	NOUN
dti-2185	155	156	fluidity	fluidity	NOUN
dti-2185	155	157	and	and	CCONJ
dti-2185	155	158	weakened	weaken	VERB
dti-2185	155	159	the	the	DET
dti-2185	155	160	interaction	interaction	NOUN
dti-2185	155	161	between	between	ADP
dti-2185	155	162	cholesterol	cholesterol	NOUN
dti-2185	155	163	and	and	CCONJ
dti-2185	155	164	sm	sm	PROPN
dti-2185	155	165	72	72	NUM
dti-2185	155	166	alkylphospholipid	alkylphospholipid	NOUN
dti-2185	155	167	2	2	NUM
dti-2185	155	168	-	-	PUNCT
dti-2185	155	169	hydroxyoleic	hydroxyoleic	ADJ
dti-2185	155	170	acid	acid	NOUN
dti-2185	155	171	(	(	PUNCT
dti-2185	155	172	≥0.1	≥0.1	NOUN
dti-2185	155	173	mol%	mol%	NOUN
dti-2185	155	174	)	)	PUNCT
dti-2185	155	175	raft	raft	NOUN
dti-2185	155	176	-	-	PUNCT
dti-2185	155	177	mimic	mimic	ADJ
dti-2185	155	178	langmuir	langmuir	NOUN
dti-2185	155	179	monolayers	monolayer	NOUN
dti-2185	155	180	(	(	PUNCT
dti-2185	155	181	sm	sm	NOUN
dti-2185	155	182	and	and	CCONJ
dti-2185	155	183	cholesterol	cholesterol	PROPN
dti-2185	155	184	,	,	PUNCT
dti-2185	155	185	2:1	2:1	NUM
dti-2185	155	186	molar	molar	ADJ
dti-2185	155	187	ratio	ratio	NOUN
dti-2185	155	188	)	)	PUNCT
dti-2185	155	189	increased	increase	VERB
dti-2185	155	190	the	the	DET
dti-2185	155	191	membrane	membrane	NOUN
dti-2185	155	192	raft	raft	NOUN
dti-2185	155	193	fluidity	fluidity	NOUN
dti-2185	155	194	73	73	NUM
dti-2185	155	195	platinum(ii	platinum(ii	ADJ
dti-2185	155	196	)	)	PUNCT
dti-2185	155	197	complex	complex	ADJ
dti-2185	155	198	cisplatin	cisplatin	NOUN
dti-2185	155	199	(	(	PUNCT
dti-2185	155	200	5	5	NUM
dti-2185	155	201	μg	μg	NOUN
dti-2185	155	202	/	/	SYM
dti-2185	155	203	ml	ml	NOUN
dti-2185	155	204	)	)	PUNCT
dti-2185	155	205	human	human	ADJ
dti-2185	155	206	colon	colon	NOUN
dti-2185	155	207	carcinoma	carcinoma	NOUN
dti-2185	155	208	cells	cell	NOUN
dti-2185	155	209	increased	increase	VERB
dti-2185	155	210	the	the	DET
dti-2185	155	211	membrane	membrane	NOUN
dti-2185	155	212	fluidity	fluidity	NOUN
dti-2185	155	213	,	,	PUNCT
dti-2185	155	214	which	which	PRON
dti-2185	155	215	was	be	AUX
dti-2185	155	216	inhibited	inhibit	VERB
dti-2185	155	217	by	by	ADP
dti-2185	155	218	10	10	NUM
dti-2185	155	219	μg	μg	NOUN
dti-2185	155	220	/	/	SYM
dti-2185	155	221	ml	ml	NOUN
dti-2185	155	222	nystatin	nystatin	PROPN
dti-2185	155	223	pretreatment	pretreatment	NOUN
dti-2185	155	224	translocated	translocate	VERB
dti-2185	155	225	cd95	cd95	PROPN
dti-2185	155	226	into	into	ADP
dti-2185	155	227	lipid	lipid	ADJ
dti-2185	155	228	rafts	raft	NOUN
dti-2185	155	229	,	,	PUNCT
dti-2185	155	230	which	which	PRON
dti-2185	155	231	was	be	AUX
dti-2185	155	232	prevented	prevent	VERB
dti-2185	155	233	by	by	ADP
dti-2185	155	234	10	10	NUM
dti-2185	155	235	μg	μg	NOUN
dti-2185	155	236	/	/	SYM
dti-2185	155	237	ml	ml	NOUN
dti-2185	155	238	nystatin	nystatin	PROPN
dti-2185	155	239	pretreatment	pretreatment	NOUN
dti-2185	155	240	75	75	NUM
dti-2185	155	241	platinum(ii	platinum(ii	NOUN
dti-2185	155	242	)	)	PUNCT
dti-2185	155	243	complex	complex	ADJ
dti-2185	155	244	cisplatin	cisplatin	NOUN
dti-2185	155	245	(	(	PUNCT
dti-2185	155	246	25	25	NUM
dti-2185	155	247	μm	μm	NUM
dti-2185	155	248	)	)	PUNCT
dti-2185	155	249	human	human	ADJ
dti-2185	155	250	colon	colon	NOUN
dti-2185	155	251	carcinoma	carcinoma	NOUN
dti-2185	155	252	cells	cell	NOUN
dti-2185	155	253	increased	increase	VERB
dti-2185	155	254	the	the	DET
dti-2185	155	255	membrane	membrane	NOUN
dti-2185	155	256	raft	raft	NOUN
dti-2185	155	257	fluidity	fluidity	NOUN
dti-2185	155	258	and	and	CCONJ
dti-2185	155	259	induced	induce	VERB
dti-2185	155	260	apoptosis	apoptosis	NOUN
dti-2185	155	261	,	,	PUNCT
dti-2185	155	262	which	which	PRON
dti-2185	155	263	was	be	AUX
dti-2185	155	264	inhibited	inhibit	VERB
dti-2185	155	265	by	by	ADP
dti-2185	155	266	cholesterol	cholesterol	NOUN
dti-2185	155	267	(	(	PUNCT
dti-2185	155	268	30	30	NUM
dti-2185	155	269	μg	μg	NOUN
dti-2185	155	270	/	/	SYM
dti-2185	155	271	ml	ml	NOUN
dti-2185	155	272	)	)	PUNCT
dti-2185	155	273	and	and	CCONJ
dti-2185	155	274	monosialoganglioside-1	monosialoganglioside-1	NUM
dti-2185	155	275	(	(	PUNCT
dti-2185	155	276	80	80	NUM
dti-2185	155	277	μm	μm	NUM
dti-2185	155	278	)	)	PUNCT
dti-2185	155	279	76	76	NUM
dti-2185	155	280	antibiotic	antibiotic	ADJ
dti-2185	155	281	azithromycin	azithromycin	NOUN
dti-2185	155	282	(	(	PUNCT
dti-2185	155	283	132	132	NUM
dti-2185	155	284	μm	μm	NOUN
dti-2185	155	285	)	)	PUNCT
dti-2185	155	286	suvs	suvs	NOUN
dti-2185	155	287	(	(	PUNCT
dti-2185	155	288	dopc	dopc	NOUN
dti-2185	155	289	,	,	PUNCT
dti-2185	155	290	sm	sm	PROPN
dti-2185	155	291	and	and	CCONJ
dti-2185	155	292	cholesterol	cholesterol	PROPN
dti-2185	155	293	,	,	PUNCT
dti-2185	155	294	1:1:1	1:1:1	PROPN
dti-2185	155	295	molar	molar	ADJ
dti-2185	155	296	ratio	ratio	NOUN
dti-2185	155	297	)	)	PUNCT
dti-2185	155	298	increased	increase	VERB
dti-2185	155	299	the	the	DET
dti-2185	155	300	fluidity	fluidity	NOUN
dti-2185	155	301	of	of	ADP
dti-2185	155	302	raft	raft	NOUN
dti-2185	155	303	-	-	PUNCT
dti-2185	155	304	like	like	ADJ
dti-2185	155	305	membranes	membrane	NOUN
dti-2185	155	306	77	77	NUM
dti-2185	155	307	antibiotic	antibiotic	ADJ
dti-2185	155	308	daunorubicin	daunorubicin	NOUN
dti-2185	155	309	(	(	PUNCT
dti-2185	155	310	40	40	NUM
dti-2185	155	311	-	-	SYM
dti-2185	155	312	75	75	NUM
dti-2185	155	313	μm	μm	NUM
dti-2185	155	314	)	)	PUNCT
dti-2185	155	315	luvs	luvs	NOUN
dti-2185	155	316	(	(	PUNCT
dti-2185	155	317	dmpc	dmpc	PROPN
dti-2185	155	318	,	,	PUNCT
dti-2185	155	319	sm	sm	PROPN
dti-2185	155	320	and	and	CCONJ
dti-2185	155	321	cholesterol	cholesterol	NOUN
dti-2185	155	322	,	,	PUNCT
dti-2185	155	323	7:1.5:1.5	7:1.5:1.5	NUM
dti-2185	155	324	molar	molar	ADJ
dti-2185	155	325	ratio	ratio	NOUN
dti-2185	155	326	)	)	PUNCT
dti-2185	155	327	decreased	decrease	VERB
dti-2185	155	328	the	the	DET
dti-2185	155	329	fluidity	fluidity	NOUN
dti-2185	155	330	of	of	ADP
dti-2185	155	331	raft	raft	NOUN
dti-2185	155	332	-	-	PUNCT
dti-2185	155	333	like	like	ADJ
dti-2185	155	334	membranes	membrane	NOUN
dti-2185	155	335	78	78	NUM
dti-2185	155	336	antibiotic	antibiotic	ADJ
dti-2185	155	337	doxorubicin	doxorubicin	NOUN
dti-2185	155	338	(	(	PUNCT
dti-2185	155	339	40	40	NUM
dti-2185	155	340	-	-	SYM
dti-2185	155	341	75	75	NUM
dti-2185	155	342	μm	μm	NUM
dti-2185	155	343	)	)	PUNCT
dti-2185	155	344	luvs	luvs	NOUN
dti-2185	155	345	(	(	PUNCT
dti-2185	155	346	dmpc	dmpc	NOUN
dti-2185	155	347	and	and	CCONJ
dti-2185	155	348	sm	sm	PROPN
dti-2185	155	349	,	,	PUNCT
dti-2185	155	350	8:2	8:2	NUM
dti-2185	155	351	molar	molar	ADJ
dti-2185	155	352	ratio	ratio	NOUN
dti-2185	155	353	or	or	CCONJ
dti-2185	155	354	dmpc	dmpc	NOUN
dti-2185	155	355	,	,	PUNCT
dti-2185	155	356	sm	sm	PROPN
dti-2185	155	357	and	and	CCONJ
dti-2185	155	358	cholesterol	cholesterol	NOUN
dti-2185	155	359	,	,	PUNCT
dti-2185	155	360	7:1.5:1.5	7:1.5:1.5	NUM
dti-2185	155	361	molar	molar	ADJ
dti-2185	155	362	ratio	ratio	NOUN
dti-2185	155	363	)	)	PUNCT
dti-2185	155	364	increased	increase	VERB
dti-2185	155	365	the	the	DET
dti-2185	155	366	fluidity	fluidity	NOUN
dti-2185	155	367	of	of	ADP
dti-2185	155	368	binary	binary	ADJ
dti-2185	155	369	membranes	membrane	NOUN
dti-2185	155	370	,	,	PUNCT
dti-2185	155	371	but	but	CCONJ
dti-2185	155	372	not	not	PART
dti-2185	155	373	ternary	ternary	ADJ
dti-2185	155	374	membranes	membrane	NOUN
dti-2185	155	375	79	79	NUM
dti-2185	155	376	dmpc	dmpc	NOUN
dti-2185	155	377	=	=	SYM
dti-2185	155	378	1,2	1,2	NUM
dti-2185	155	379	-	-	PUNCT
dti-2185	155	380	dimyristoylphosphatidylcholine	dimyristoylphosphatidylcholine	NOUN
dti-2185	155	381	;	;	PUNCT
dti-2185	155	382	dopc	dopc	NOUN
dti-2185	155	383	=	=	SYM
dti-2185	155	384	1,2	1,2	NUM
dti-2185	155	385	-	-	PUNCT
dti-2185	155	386	dioleoylphosphatidylcholine	dioleoylphosphatidylcholine	NOUN
dti-2185	155	387	;	;	PUNCT
dti-2185	155	388	guv	guv	NOUN
dti-2185	155	389	=	=	SYM
dti-2185	155	390	giant	giant	ADJ
dti-2185	155	391	unilamellar	unilamellar	ADJ
dti-2185	155	392	vesicle	vesicle	NOUN
dti-2185	155	393	;	;	PUNCT
dti-2185	155	394	luv	luv	NOUN
dti-2185	155	395	=	=	PROPN
dti-2185	155	396	large	large	ADJ
dti-2185	155	397	unilamellar	unilamellar	ADJ
dti-2185	155	398	vesicle	vesicle	NOUN
dti-2185	155	399	;	;	PUNCT
dti-2185	155	400	mlv	mlv	ADJ
dti-2185	155	401	=	=	SYM
dti-2185	155	402	multilamellar	multilamellar	ADJ
dti-2185	155	403	vesicle	vesicle	NOUN
dti-2185	155	404	;	;	PUNCT
dti-2185	155	405	odpc	odpc	ADV
dti-2185	155	406	=	=	SYM
dti-2185	155	407	10-(octyloxy	10-(octyloxy	NUM
dti-2185	155	408	)	)	PUNCT
dti-2185	155	409	decyl-2-(trimethylammonium	decyl-2-(trimethylammonium	NOUN
dti-2185	155	410	)	)	PUNCT
dti-2185	155	411	ethyl	ethyl	PROPN
dti-2185	155	412	phosphate	phosphate	NOUN
dti-2185	155	413	;	;	PUNCT
dti-2185	155	414	popc	popc	NOUN
dti-2185	155	415	=	=	SYM
dti-2185	155	416	1	1	NUM
dti-2185	155	417	-	-	PUNCT
dti-2185	155	418	palmitoyl-2	palmitoyl-2	VERB
dti-2185	155	419	-	-	PUNCT
dti-2185	155	420	oleoylphosphatidylcholine	oleoylphosphatidylcholine	NOUN
dti-2185	155	421	;	;	PUNCT
dti-2185	155	422	sm	sm	PROPN
dti-2185	155	423	=	=	SYM
dti-2185	155	424	sphingomyelin	sphingomyelin	NOUN
dti-2185	155	425	;	;	PUNCT
dti-2185	155	426	suv	suv	X
dti-2185	155	427	=	=	SYM
dti-2185	155	428	small	small	ADJ
dti-2185	155	429	unilamellar	unilamellar	ADJ
dti-2185	155	430	vesicle	vesicle	NOUN
dti-2185	155	431	;	;	PUNCT
dti-2185	155	432	ulv	ulv	ADJ
dti-2185	155	433	=	=	SYM
dti-2185	155	434	unilamellar	unilamellar	ADJ
dti-2185	155	435	vesicle	vesicle	NOUN
dti-2185	155	436	.	.	PUNCT
dti-2185	156	1	analysis	analysis	NOUN
dti-2185	156	2	.	.	PUNCT
dti-2185	157	1	cisplatin	cisplatin	PROPN
dti-2185	157	2	increased	increase	VERB
dti-2185	157	3	the	the	DET
dti-2185	157	4	fluidity	fluidity	NOUN
dti-2185	157	5	of	of	ADP
dti-2185	157	6	plasma	plasma	NOUN
dti-2185	157	7	membranes	membrane	NOUN
dti-2185	157	8	as	as	ADV
dti-2185	157	9	soon	soon	ADV
dti-2185	157	10	as	as	ADP
dti-2185	157	11	0.25	0.25	NUM
dti-2185	157	12	hours	hour	NOUN
dti-2185	157	13	after	after	ADP
dti-2185	157	14	the	the	DET
dti-2185	157	15	treatment	treatment	NOUN
dti-2185	157	16	,	,	PUNCT
dti-2185	157	17	although	although	SCONJ
dti-2185	157	18	its	its	PRON
dti-2185	157	19	membrane	membrane	NOUN
dti-2185	157	20	effect	effect	NOUN
dti-2185	157	21	was	be	AUX
dti-2185	157	22	inhibited	inhibit	VERB
dti-2185	157	23	by	by	ADP
dti-2185	157	24	pretreating	pretreate	VERB
dti-2185	157	25	with	with	ADP
dti-2185	157	26	cholesterol	cholesterol	NOUN
dti-2185	157	27	sequestering	sequestering	NOUN
dti-2185	157	28	nystatin	nystatin	NOUN
dti-2185	157	29	at	at	ADP
dti-2185	157	30	10	10	NUM
dti-2185	157	31	μg	μg	NOUN
dti-2185	157	32	/	/	SYM
dti-2185	157	33	ml	ml	PROPN
dti-2185	157	34	.	.	PUNCT
dti-2185	158	1	the	the	DET
dti-2185	158	2	cell	cell	NOUN
dti-2185	158	3	exposure	exposure	NOUN
dti-2185	158	4	to	to	ADP
dti-2185	158	5	cisplatin	cisplatin	NOUN
dti-2185	158	6	for	for	ADP
dti-2185	158	7	4	4	NUM
dti-2185	158	8	hours	hour	NOUN
dti-2185	158	9	induced	induce	VERB
dti-2185	158	10	the	the	DET
dti-2185	158	11	translocation	translocation	NOUN
dti-2185	158	12	of	of	ADP
dti-2185	158	13	cd95	cd95	PROPN
dti-2185	158	14	(	(	PUNCT
dti-2185	158	15	cluster	cluster	NOUN
dti-2185	158	16	of	of	ADP
dti-2185	158	17	differentiation	differentiation	NOUN
dti-2185	158	18	95	95	NUM
dti-2185	158	19	known	know	VERB
dti-2185	158	20	as	as	ADP
dti-2185	158	21	fas	fas	PROPN
dti-2185	158	22	receptor	receptor	NOUN
dti-2185	158	23	)	)	PUNCT
dti-2185	158	24	into	into	ADP
dti-2185	158	25	lipid	lipid	NOUN
dti-2185	158	26	rafts	raft	NOUN
dti-2185	158	27	,	,	PUNCT
dti-2185	158	28	which	which	PRON
dti-2185	158	29	was	be	AUX
dti-2185	158	30	prevented	prevent	VERB
dti-2185	158	31	by	by	ADP
dti-2185	158	32	nystatin	nystatin	NOUN
dti-2185	158	33	pretreated	pretreate	VERB
dti-2185	158	34	at	at	ADP
dti-2185	158	35	10	10	NUM
dti-2185	158	36	μg/	μg/	NOUN
dti-2185	158	37	ml	ml	NOUN
dti-2185	158	38	.	.	PUNCT
dti-2185	159	1	rebillard	rebillard	NOUN
dti-2185	159	2	et	et	PROPN
dti-2185	159	3	al	al	PROPN
dti-2185	159	4	treated	treat	VERB
dti-2185	159	5	human	human	ADJ
dti-2185	159	6	colon	colon	NOUN
dti-2185	159	7	carcinoma	carcinoma	NOUN
dti-2185	159	8	(	(	PUNCT
dti-2185	159	9	ht29	ht29	PROPN
dti-2185	159	10	)	)	PUNCT
dti-2185	159	11	cells	cell	NOUN
dti-2185	159	12	growing	grow	VERB
dti-2185	159	13	in	in	ADP
dti-2185	159	14	the	the	DET
dti-2185	159	15	exponential	exponential	ADJ
dti-2185	159	16	phase	phase	NOUN
dti-2185	159	17	with	with	ADP
dti-2185	159	18	cisplatin	cisplatin	NOUN
dti-2185	159	19	at	at	ADP
dti-2185	159	20	25	25	NUM
dti-2185	159	21	μm	μm	NOUN
dti-2185	159	22	for	for	ADP
dti-2185	159	23	1	1	NUM
dti-2185	159	24	-	-	SYM
dti-2185	159	25	72	72	NUM
dti-2185	159	26	hours	hour	NOUN
dti-2185	159	27	(	(	PUNCT
dti-2185	159	28	76	76	NUM
dti-2185	159	29	)	)	PUNCT
dti-2185	159	30	.	.	PUNCT
dti-2185	160	1	they	they	PRON
dti-2185	160	2	isolated	isolate	VERB
dti-2185	160	3	lipid	lipid	NOUN
dti-2185	160	4	rafts	raft	NOUN
dti-2185	160	5	by	by	ADP
dti-2185	160	6	sdgc	sdgc	NOUN
dti-2185	160	7	and	and	CCONJ
dti-2185	160	8	performed	perform	VERB
dti-2185	160	9	epr	epr	PROPN
dti-2185	160	10	spectroscopic	spectroscopic	ADJ
dti-2185	160	11	analysis	analysis	NOUN
dti-2185	160	12	after	after	ADP
dti-2185	160	13	12	12	NUM
dti-2185	160	14	-	-	PUNCT
dti-2185	160	15	dsa	dsa	NOUN
dti-2185	160	16	spin	spin	NOUN
dti-2185	160	17	labeling	labeling	NOUN
dti-2185	160	18	.	.	PUNCT
dti-2185	161	1	cisplatin	cisplatin	NOUN
dti-2185	161	2	treatment	treatment	NOUN
dti-2185	161	3	for	for	ADP
dti-2185	161	4	1	1	NUM
dti-2185	161	5	hour	hour	NOUN
dti-2185	161	6	increased	increase	VERB
dti-2185	161	7	membrane	membrane	NOUN
dti-2185	161	8	raft	raft	NOUN
dti-2185	161	9	fluidity	fluidity	NOUN
dti-2185	161	10	and	and	CCONJ
dti-2185	161	11	that	that	SCONJ
dti-2185	161	12	for	for	ADP
dti-2185	161	13	72	72	NUM
dti-2185	161	14	hours	hour	NOUN
dti-2185	161	15	induced	induce	VERB
dti-2185	161	16	apoptosis	apoptosis	NOUN
dti-2185	161	17	.	.	PUNCT
dti-2185	162	1	such	such	ADJ
dti-2185	162	2	effects	effect	NOUN
dti-2185	162	3	were	be	AUX
dti-2185	162	4	inhibited	inhibit	VERB
dti-2185	162	5	by	by	ADP
dti-2185	162	6	membrane	membrane	NOUN
dti-2185	162	7	-	-	PUNCT
dti-2185	162	8	stabilizing	stabilize	VERB
dti-2185	162	9	cholesterol	cholesterol	NOUN
dti-2185	162	10	(	(	PUNCT
dti-2185	162	11	30	30	NUM
dti-2185	162	12	μg	μg	NOUN
dti-2185	162	13	/	/	SYM
dti-2185	162	14	ml	ml	NOUN
dti-2185	162	15	)	)	PUNCT
dti-2185	162	16	and	and	CCONJ
dti-2185	162	17	monosialoganglioside-1	monosialoganglioside-1	NUM
dti-2185	162	18	(	(	PUNCT
dti-2185	162	19	80	80	NUM
dti-2185	162	20	μm	μm	NUM
dti-2185	162	21	)	)	PUNCT
dti-2185	162	22	.	.	PUNCT
dti-2185	163	1	anticancer	anticancer	NOUN
dti-2185	163	2	antibiotics	antibiotic	NOUN
dti-2185	163	3	berquand	berquand	NOUN
dti-2185	163	4	et	et	PROPN
dti-2185	163	5	al	al	PROPN
dti-2185	163	6	treated	treat	VERB
dti-2185	163	7	suvs	suvs	NOUN
dti-2185	163	8	prepared	prepare	VERB
dti-2185	163	9	with	with	ADP
dti-2185	163	10	dopc	dopc	NOUN
dti-2185	163	11	,	,	PUNCT
dti-2185	163	12	sm	sm	PROPN
dti-2185	163	13	and	and	CCONJ
dti-2185	163	14	cholesterol	cholesterol	NOUN
dti-2185	163	15	(	(	PUNCT
dti-2185	163	16	1:1:1	1:1:1	PROPN
dti-2185	163	17	molar	molar	ADJ
dti-2185	163	18	ratio	ratio	NOUN
dti-2185	163	19	)	)	PUNCT
dti-2185	163	20	with	with	ADP
dti-2185	163	21	macrolide	macrolide	ADJ
dti-2185	163	22	antibiotic	antibiotic	ADJ
dti-2185	163	23	azithromycin	azithromycin	NOUN
dti-2185	163	24	(	(	PUNCT
dti-2185	163	25	77	77	NUM
dti-2185	163	26	)	)	PUNCT
dti-2185	163	27	.	.	PUNCT
dti-2185	164	1	fp	fp	DET
dti-2185	164	2	analysis	analysis	NOUN
dti-2185	164	3	revealed	reveal	VERB
dti-2185	164	4	that	that	SCONJ
dti-2185	164	5	azithromycin	azithromycin	PROPN
dti-2185	164	6	increases	increase	VERB
dti-2185	164	7	the	the	DET
dti-2185	164	8	fluidity	fluidity	NOUN
dti-2185	164	9	of	of	ADP
dti-2185	164	10	a	a	DET
dti-2185	164	11	hydrophobic	hydrophobic	NOUN
dti-2185	164	12	region	region	NOUN
dti-2185	164	13	of	of	ADP
dti-2185	164	14	raft	raft	NOUN
dti-2185	164	15	-	-	PUNCT
dti-2185	164	16	like	like	ADJ
dti-2185	164	17	membranes	membrane	NOUN
dti-2185	164	18	at	at	ADP
dti-2185	164	19	132	132	NUM
dti-2185	164	20	μm	μm	NOUN
dti-2185	164	21	.	.	PUNCT
dti-2185	165	1	in	in	ADP
dti-2185	165	2	fa	fa	NOUN
dti-2185	165	3	experiments	experiment	NOUN
dti-2185	165	4	of	of	ADP
dti-2185	165	5	alves	alves	PROPN
dti-2185	165	6	et	et	PROPN
dti-2185	165	7	al	al	PROPN
dti-2185	165	8	(	(	PUNCT
dti-2185	165	9	78	78	NUM
dti-2185	165	10	)	)	PUNCT
dti-2185	165	11	,	,	PUNCT
dti-2185	165	12	anthracycline	anthracycline	VERB
dti-2185	165	13	antibiotic	antibiotic	ADJ
dti-2185	165	14	daunorubicin	daunorubicin	NOUN
dti-2185	165	15	(	(	PUNCT
dti-2185	165	16	40	40	NUM
dti-2185	165	17	-	-	SYM
dti-2185	165	18	75	75	NUM
dti-2185	165	19	μm	μm	NUM
dti-2185	165	20	)	)	PUNCT
dti-2185	165	21	decreased	decrease	VERB
dti-2185	165	22	the	the	DET
dti-2185	165	23	fluidity	fluidity	NOUN
dti-2185	165	24	of	of	ADP
dti-2185	165	25	raft	raft	NOUN
dti-2185	165	26	-	-	PUNCT
dti-2185	165	27	like	like	ADJ
dti-2185	165	28	membranes	membrane	NOUN
dti-2185	165	29	of	of	ADP
dti-2185	165	30	luvs	luvs	PROPN
dti-2185	165	31	prepared	prepare	VERB
dti-2185	165	32	with	with	ADP
dti-2185	165	33	dmpc	dmpc	NOUN
dti-2185	165	34	,	,	PUNCT
dti-2185	165	35	sm	sm	PROPN
dti-2185	165	36	and	and	CCONJ
dti-2185	165	37	cholesterol	cholesterol	NOUN
dti-2185	165	38	(	(	PUNCT
dti-2185	165	39	7:1.5:1.5	7:1.5:1.5	NUM
dti-2185	165	40	molar	molar	ADJ
dti-2185	165	41	ratio	ratio	NOUN
dti-2185	165	42	)	)	PUNCT
dti-2185	165	43	,	,	PUNCT
dti-2185	165	44	while	while	SCONJ
dti-2185	165	45	this	this	DET
dti-2185	165	46	antibiotic	antibiotic	NOUN
dti-2185	165	47	was	be	AUX
dti-2185	165	48	more	more	ADV
dti-2185	165	49	effective	effective	ADJ
dti-2185	165	50	in	in	ADP
dti-2185	165	51	decreasing	decrease	VERB
dti-2185	165	52	the	the	DET
dti-2185	165	53	membrane	membrane	NOUN
dti-2185	165	54	fluidity	fluidity	NOUN
dti-2185	165	55	of	of	ADP
dti-2185	165	56	luvs	luvs	PROPN
dti-2185	165	57	prepared	prepare	VERB
dti-2185	165	58	without	without	ADP
dti-2185	165	59	cholesterol	cholesterol	NOUN
dti-2185	165	60	.	.	PUNCT
dti-2185	166	1	alves	alves	PROPN
dti-2185	166	2	et	et	PROPN
dti-2185	166	3	al	al	PROPN
dti-2185	166	4	also	also	ADV
dti-2185	166	5	investigated	investigate	VERB
dti-2185	166	6	the	the	DET
dti-2185	166	7	effects	effect	NOUN
dti-2185	166	8	of	of	ADP
dti-2185	166	9	doxorubicin	doxorubicin	PROPN
dti-2185	166	10	on	on	ADP
dti-2185	166	11	luvs	luvs	PROPN
dti-2185	166	12	prepared	prepare	VERB
dti-2185	166	13	with	with	ADP
dti-2185	166	14	dmpc	dmpc	NOUN
dti-2185	166	15	and	and	CCONJ
dti-2185	166	16	sm	sm	PROPN
dti-2185	166	17	(	(	PUNCT
dti-2185	166	18	8:2	8:2	NUM
dti-2185	166	19	molar	molar	ADJ
dti-2185	166	20	ratio	ratio	NOUN
dti-2185	166	21	)	)	PUNCT
dti-2185	166	22	or	or	CCONJ
dti-2185	166	23	with	with	ADP
dti-2185	166	24	dmpc	dmpc	NOUN
dti-2185	166	25	,	,	PUNCT
dti-2185	166	26	sm	sm	PROPN
dti-2185	166	27	and	and	CCONJ
dti-2185	166	28	cholesterol	cholesterol	NOUN
dti-2185	166	29	(	(	PUNCT
dti-2185	166	30	7:1.5:1.5	7:1.5:1.5	NUM
dti-2185	166	31	molar	molar	ADJ
dti-2185	166	32	ratio	ratio	NOUN
dti-2185	166	33	)	)	PUNCT
dti-2185	166	34	by	by	ADP
dti-2185	166	35	measuring	measure	VERB
dti-2185	166	36	fa	fa	PROPN
dti-2185	166	37	(	(	PUNCT
dti-2185	166	38	79	79	NUM
dti-2185	166	39	)	)	PUNCT
dti-2185	166	40	.	.	PUNCT
dti-2185	167	1	doxorubicin	doxorubicin	PROPN
dti-2185	167	2	increased	increase	VERB
dti-2185	167	3	the	the	DET
dti-2185	167	4	fluidity	fluidity	NOUN
dti-2185	167	5	of	of	ADP
dti-2185	167	6	binary	binary	ADJ
dti-2185	167	7	membranes	membrane	NOUN
dti-2185	167	8	at	at	ADP
dti-2185	167	9	40	40	NUM
dti-2185	167	10	-	-	SYM
dti-2185	167	11	75	75	NUM
dti-2185	167	12	μm	μm	NUM
dti-2185	167	13	,	,	PUNCT
dti-2185	167	14	but	but	CCONJ
dti-2185	167	15	not	not	PART
dti-2185	167	16	raft	raft	VERB
dti-2185	167	17	-	-	PUNCT
dti-2185	167	18	like	like	ADJ
dti-2185	167	19	ternary	ternary	ADJ
dti-2185	167	20	membranes	membrane	NOUN
dti-2185	167	21	containing	contain	VERB
dti-2185	167	22	cholesterol	cholesterol	NOUN
dti-2185	167	23	.	.	PUNCT
dti-2185	168	1	phytochemicals	phytochemical	NOUN
dti-2185	168	2	a	a	DET
dti-2185	168	3	variety	variety	NOUN
dti-2185	168	4	of	of	ADP
dti-2185	168	5	phytochemicals	phytochemical	NOUN
dti-2185	168	6	(	(	PUNCT
dti-2185	168	7	bioactive	bioactive	NOUN
dti-2185	168	8	components	component	NOUN
dti-2185	168	9	in	in	ADP
dti-2185	168	10	plants	plant	NOUN
dti-2185	168	11	)	)	PUNCT
dti-2185	168	12	such	such	ADJ
dti-2185	168	13	as	as	ADP
dti-2185	168	14	flavonoids	flavonoid	NOUN
dti-2185	168	15	exhibit	exhibit	VERB
dti-2185	168	16	a	a	DET
dti-2185	168	17	broad	broad	ADJ
dti-2185	168	18	spectrum	spectrum	NOUN
dti-2185	168	19	of	of	ADP
dti-2185	168	20	pharmacological	pharmacological	ADJ
dti-2185	168	21	activity	activity	NOUN
dti-2185	168	22	including	include	VERB
dti-2185	168	23	antioxidant	antioxidant	NOUN
dti-2185	168	24	,	,	PUNCT
dti-2185	168	25	antitumor	antitumor	PROPN
dti-2185	168	26	,	,	PUNCT
dti-2185	168	27	interaction	interaction	NOUN
dti-2185	168	28	of	of	ADP
dti-2185	168	29	drugs	drug	NOUN
dti-2185	168	30	with	with	ADP
dti-2185	168	31	lipid	lipid	ADJ
dti-2185	168	32	rafts42	rafts42	NOUN
dti-2185	169	1	©	©	PROPN
dti-2185	169	2	2020	2020	NUM
dti-2185	169	3	the	the	DET
dti-2185	169	4	authors	author	NOUN
dti-2185	169	5	.	.	PUNCT
dti-2185	170	1	published	publish	VERB
dti-2185	170	2	by	by	ADP
dti-2185	170	3	aboutscience	aboutscience	NOUN
dti-2185	170	4	anti	anti	ADJ
dti-2185	170	5	-	-	ADJ
dti-2185	170	6	inflammatory	inflammatory	ADJ
dti-2185	170	7	,	,	PUNCT
dti-2185	170	8	analgesic	analgesic	ADJ
dti-2185	170	9	,	,	PUNCT
dti-2185	170	10	antimicrobial	antimicrobial	ADJ
dti-2185	170	11	,	,	PUNCT
dti-2185	170	12	cardioprotective	cardioprotective	ADJ
dti-2185	170	13	,	,	PUNCT
dti-2185	170	14	anti	anti	ADJ
dti-2185	170	15	-	-	ADJ
dti-2185	170	16	allergic	allergic	ADJ
dti-2185	170	17	and	and	CCONJ
dti-2185	170	18	antiplatelet	antiplatelet	NOUN
dti-2185	170	19	ones	one	NOUN
dti-2185	170	20	.	.	PUNCT
dti-2185	171	1	many	many	ADJ
dti-2185	171	2	of	of	ADP
dti-2185	171	3	them	they	PRON
dti-2185	171	4	with	with	ADP
dti-2185	171	5	the	the	DET
dti-2185	171	6	amphiphilic	amphiphilic	ADJ
dti-2185	171	7	structure	structure	NOUN
dti-2185	171	8	share	share	VERB
dti-2185	171	9	the	the	DET
dti-2185	171	10	property	property	NOUN
dti-2185	171	11	to	to	PART
dti-2185	171	12	interact	interact	VERB
dti-2185	171	13	with	with	ADP
dti-2185	171	14	artificial	artificial	ADJ
dti-2185	171	15	and	and	CCONJ
dti-2185	171	16	biological	biological	ADJ
dti-2185	171	17	membranes	membrane	NOUN
dti-2185	171	18	.	.	PUNCT
dti-2185	172	1	the	the	DET
dti-2185	172	2	membrane	membrane	NOUN
dti-2185	172	3	interactivity	interactivity	NOUN
dti-2185	172	4	of	of	ADP
dti-2185	172	5	phytochemicals	phytochemical	NOUN
dti-2185	172	6	was	be	AUX
dti-2185	172	7	recently	recently	ADV
dti-2185	172	8	reviewed	review	VERB
dti-2185	172	9	by	by	ADP
dti-2185	172	10	tsuchiya	tsuchiya	PROPN
dti-2185	172	11	(	(	PUNCT
dti-2185	172	12	80	80	NUM
dti-2185	172	13	)	)	PUNCT
dti-2185	172	14	,	,	PUNCT
dti-2185	172	15	especially	especially	ADV
dti-2185	172	16	the	the	DET
dti-2185	172	17	interaction	interaction	NOUN
dti-2185	172	18	of	of	ADP
dti-2185	172	19	flavonoids	flavonoid	NOUN
dti-2185	172	20	with	with	ADP
dti-2185	172	21	lipid	lipid	ADJ
dti-2185	172	22	rafts	raft	NOUN
dti-2185	172	23	by	by	ADP
dti-2185	172	24	tarahovsky	tarahovsky	NOUN
dti-2185	172	25	et	et	PROPN
dti-2185	172	26	al	al	PROPN
dti-2185	172	27	(	(	PUNCT
dti-2185	172	28	81	81	NUM
dti-2185	172	29	)	)	PUNCT
dti-2185	172	30	and	and	CCONJ
dti-2185	172	31	their	their	PRON
dti-2185	172	32	induced	induce	VERB
dti-2185	172	33	changes	change	NOUN
dti-2185	172	34	in	in	ADP
dti-2185	172	35	membrane	membrane	NOUN
dti-2185	172	36	fluidity	fluidity	NOUN
dti-2185	172	37	by	by	ADP
dti-2185	172	38	selvaraj	selvaraj	PROPN
dti-2185	172	39	et	et	PROPN
dti-2185	172	40	al	al	PROPN
dti-2185	172	41	(	(	PUNCT
dti-2185	172	42	82	82	NUM
dti-2185	172	43	)	)	PUNCT
dti-2185	172	44	.	.	PUNCT
dti-2185	173	1	results	result	NOUN
dti-2185	173	2	of	of	ADP
dti-2185	173	3	the	the	DET
dti-2185	173	4	literature	literature	NOUN
dti-2185	173	5	search	search	NOUN
dti-2185	173	6	on	on	ADP
dti-2185	173	7	the	the	DET
dti-2185	173	8	interaction	interaction	NOUN
dti-2185	173	9	of	of	ADP
dti-2185	173	10	phytochemicals	phytochemical	NOUN
dti-2185	173	11	with	with	ADP
dti-2185	173	12	membrane	membrane	NOUN
dti-2185	173	13	lipid	lipid	NOUN
dti-2185	173	14	rafts	raft	NOUN
dti-2185	173	15	and	and	CCONJ
dti-2185	173	16	membranes	membrane	NOUN
dti-2185	173	17	are	be	AUX
dti-2185	173	18	shown	show	VERB
dti-2185	173	19	in	in	ADP
dti-2185	173	20	table	table	NOUN
dti-2185	173	21	v.	v.	ADP
dti-2185	173	22	table	table	NOUN
dti-2185	173	23	v	v	ADP
dti-2185	173	24	interaction	interaction	NOUN
dti-2185	173	25	of	of	ADP
dti-2185	173	26	phytochemicals	phytochemical	NOUN
dti-2185	173	27	with	with	ADP
dti-2185	173	28	lipid	lipid	ADJ
dti-2185	173	29	raft	raft	NOUN
dti-2185	173	30	membrane	membrane	NOUN
dti-2185	173	31	domains	domain	NOUN
dti-2185	173	32	and	and	CCONJ
dti-2185	173	33	membranes	membrane	NOUN
dti-2185	173	34	drug	drug	NOUN
dti-2185	173	35	class	class	NOUN
dti-2185	173	36	drug	drug	NOUN
dti-2185	173	37	membrane	membrane	NOUN
dti-2185	173	38	induced	induce	VERB
dti-2185	173	39	membrane	membrane	NOUN
dti-2185	173	40	modification	modification	NOUN
dti-2185	173	41	reference	reference	NOUN
dti-2185	173	42	flavonoid	flavonoid	NOUN
dti-2185	173	43	quercetin	quercetin	NOUN
dti-2185	173	44	(	(	PUNCT
dti-2185	173	45	10	10	NUM
dti-2185	173	46	μm	μm	NOUN
dti-2185	173	47	)	)	PUNCT
dti-2185	173	48	egcg	egcg	NOUN
dti-2185	173	49	(	(	PUNCT
dti-2185	173	50	10	10	NUM
dti-2185	173	51	μm	μm	NOUN
dti-2185	173	52	)	)	PUNCT
dti-2185	173	53	cyanidin	cyanidin	VERB
dti-2185	173	54	(	(	PUNCT
dti-2185	173	55	10	10	NUM
dti-2185	173	56	μm	μm	NOUN
dti-2185	173	57	)	)	PUNCT
dti-2185	173	58	suvs	suvs	NOUN
dti-2185	173	59	(	(	PUNCT
dti-2185	173	60	phospholipids	phospholipid	NOUN
dti-2185	173	61	(	(	PUNCT
dti-2185	173	62	popc	popc	NOUN
dti-2185	173	63	and	and	CCONJ
dti-2185	173	64	sm	sm	NOUN
dti-2185	173	65	)	)	PUNCT
dti-2185	173	66	and	and	CCONJ
dti-2185	173	67	cholesterol	cholesterol	NOUN
dti-2185	173	68	by	by	ADP
dti-2185	173	69	varying	vary	VERB
dti-2185	173	70	the	the	DET
dti-2185	173	71	composition	composition	NOUN
dti-2185	173	72	55	55	NUM
dti-2185	173	73	-	-	SYM
dti-2185	173	74	80	80	NUM
dti-2185	173	75	mol%	mol%	NOUN
dti-2185	173	76	and	and	CCONJ
dti-2185	173	77	20	20	NUM
dti-2185	173	78	-	-	SYM
dti-2185	173	79	45	45	NUM
dti-2185	173	80	mol%	mol%	NOUN
dti-2185	173	81	)	)	PUNCT
dti-2185	173	82	quercetin	quercetin	NOUN
dti-2185	173	83	decreased	decrease	VERB
dti-2185	173	84	the	the	DET
dti-2185	173	85	membrane	membrane	NOUN
dti-2185	173	86	fluidity	fluidity	NOUN
dti-2185	173	87	most	most	ADV
dti-2185	173	88	potently	potently	ADV
dti-2185	173	89	,	,	PUNCT
dti-2185	173	90	followed	follow	VERB
dti-2185	173	91	by	by	ADP
dti-2185	173	92	cyanidin	cyanidin	VERB
dti-2185	173	93	and	and	CCONJ
dti-2185	173	94	egcg	egcg	VERB
dti-2185	173	95	84	84	NUM
dti-2185	173	96	flavonoid	flavonoid	NOUN
dti-2185	173	97	quercetin	quercetin	NOUN
dti-2185	173	98	(	(	PUNCT
dti-2185	173	99	30	30	NUM
dti-2185	173	100	μm	μm	NUM
dti-2185	173	101	)	)	PUNCT
dti-2185	173	102	human	human	ADJ
dti-2185	173	103	colon	colon	NOUN
dti-2185	173	104	cancer	cancer	NOUN
dti-2185	173	105	cells	cell	NOUN
dti-2185	173	106	(	(	PUNCT
dti-2185	173	107	ht-29	ht-29	X
dti-2185	173	108	,	,	PUNCT
dti-2185	173	109	sw-620	sw-620	NOUN
dti-2185	173	110	and	and	CCONJ
dti-2185	173	111	caco-2	caco-2	NOUN
dti-2185	173	112	)	)	PUNCT
dti-2185	173	113	enhanced	enhance	VERB
dti-2185	173	114	trail	trail	NOUN
dti-2185	173	115	efficacy	efficacy	NOUN
dti-2185	173	116	to	to	PART
dti-2185	173	117	induce	induce	VERB
dti-2185	173	118	apoptosis	apoptosis	NOUN
dti-2185	173	119	by	by	ADP
dti-2185	173	120	accumulating	accumulate	VERB
dti-2185	173	121	death	death	NOUN
dti-2185	173	122	receptors	receptor	NOUN
dti-2185	173	123	in	in	ADP
dti-2185	173	124	membrane	membrane	NOUN
dti-2185	173	125	lipid	lipid	NOUN
dti-2185	173	126	rafts	raft	NOUN
dti-2185	173	127	85	85	NUM
dti-2185	173	128	flavonoid	flavonoid	NOUN
dti-2185	173	129	quercetin	quercetin	NOUN
dti-2185	173	130	(	(	PUNCT
dti-2185	173	131	10	10	NUM
dti-2185	173	132	and	and	CCONJ
dti-2185	173	133	100	100	NUM
dti-2185	173	134	μm	μm	NUM
dti-2185	173	135	)	)	PUNCT
dti-2185	173	136	luteolin	luteolin	PROPN
dti-2185	173	137	(	(	PUNCT
dti-2185	173	138	10	10	NUM
dti-2185	173	139	and	and	CCONJ
dti-2185	173	140	100	100	NUM
dti-2185	173	141	μm	μm	NUM
dti-2185	173	142	)	)	PUNCT
dti-2185	173	143	mouse	mouse	NOUN
dti-2185	173	144	macrophages	macrophage	NOUN
dti-2185	173	145	suppressed	suppress	VERB
dti-2185	173	146	the	the	DET
dti-2185	173	147	accumulation	accumulation	NOUN
dti-2185	173	148	of	of	ADP
dti-2185	173	149	lipid	lipid	ADJ
dti-2185	173	150	rafts	raft	NOUN
dti-2185	173	151	to	to	PART
dti-2185	173	152	inhibit	inhibit	VERB
dti-2185	173	153	tnf	tnf	PROPN
dti-2185	173	154	-	-	PUNCT
dti-2185	173	155	α	α	PROPN
dti-2185	173	156	production	production	NOUN
dti-2185	173	157	86	86	NUM
dti-2185	173	158	flavonoid	flavonoid	NOUN
dti-2185	173	159	quercetin	quercetin	NOUN
dti-2185	173	160	(	(	PUNCT
dti-2185	173	161	2	2	NUM
dti-2185	173	162	-	-	SYM
dti-2185	173	163	16	16	NUM
dti-2185	173	164	μm	μm	NUM
dti-2185	173	165	)	)	PUNCT
dti-2185	173	166	suvs	suvs	NOUN
dti-2185	173	167	(	(	PUNCT
dti-2185	173	168	dmpc	dmpc	NOUN
dti-2185	173	169	plus	plus	CCONJ
dti-2185	173	170	20	20	NUM
dti-2185	173	171	or	or	CCONJ
dti-2185	173	172	33	33	NUM
dti-2185	173	173	mol%	mol%	PROPN
dti-2185	173	174	cholesterol	cholesterol	NOUN
dti-2185	173	175	)	)	PUNCT
dti-2185	173	176	increased	increase	VERB
dti-2185	173	177	the	the	DET
dti-2185	173	178	fluidity	fluidity	NOUN
dti-2185	173	179	of	of	ADP
dti-2185	173	180	raft	raft	NOUN
dti-2185	173	181	model	model	NOUN
dti-2185	173	182	membranes	membrane	NOUN
dti-2185	173	183	87	87	NUM
dti-2185	173	184	flavonoid	flavonoid	NOUN
dti-2185	173	185	egcg	egcg	NOUN
dti-2185	173	186	(	(	PUNCT
dti-2185	173	187	5	5	NUM
dti-2185	173	188	-	-	SYM
dti-2185	173	189	100	100	NUM
dti-2185	173	190	μm	μm	NUM
dti-2185	173	191	)	)	PUNCT
dti-2185	173	192	suvs	suvs	NOUN
dti-2185	173	193	(	(	PUNCT
dti-2185	173	194	5	5	NUM
dti-2185	173	195	mol%	mol%	PROPN
dti-2185	173	196	cholesterol	cholesterol	NOUN
dti-2185	173	197	and	and	CCONJ
dti-2185	173	198	95	95	NUM
dti-2185	173	199	mol%	mol%	PROPN
dti-2185	173	200	popc	popc	NOUN
dti-2185	173	201	or	or	CCONJ
dti-2185	173	202	dopc	dopc	NOUN
dti-2185	173	203	)	)	PUNCT
dti-2185	173	204	decreased	decrease	VERB
dti-2185	173	205	the	the	DET
dti-2185	173	206	fluidity	fluidity	NOUN
dti-2185	173	207	of	of	ADP
dti-2185	173	208	binary	binary	ADJ
dti-2185	173	209	membranes	membrane	NOUN
dti-2185	173	210	88	88	NUM
dti-2185	173	211	flavonoid	flavonoid	NOUN
dti-2185	173	212	egcg	egcg	NOUN
dti-2185	173	213	(	(	PUNCT
dti-2185	173	214	5	5	NUM
dti-2185	173	215	-	-	SYM
dti-2185	173	216	20	20	NUM
dti-2185	173	217	μg	μg	NOUN
dti-2185	173	218	/	/	SYM
dti-2185	173	219	ml	ml	NOUN
dti-2185	173	220	)	)	PUNCT
dti-2185	173	221	human	human	ADJ
dti-2185	173	222	colon	colon	NOUN
dti-2185	173	223	carcinoma	carcinoma	NOUN
dti-2185	173	224	cells	cell	NOUN
dti-2185	173	225	reduced	reduce	VERB
dti-2185	173	226	the	the	DET
dti-2185	173	227	membrane	membrane	NOUN
dti-2185	173	228	resistance	resistance	NOUN
dti-2185	173	229	to	to	ADP
dti-2185	173	230	triton	triton	PROPN
dti-2185	173	231	x-100	x-100	PROPN
dti-2185	173	232	by	by	ADP
dti-2185	173	233	decreasing	decrease	VERB
dti-2185	173	234	ordered	order	VERB
dti-2185	173	235	membrane	membrane	NOUN
dti-2185	173	236	domains	domain	NOUN
dti-2185	173	237	89	89	NUM
dti-2185	173	238	flavonoid	flavonoid	NOUN
dti-2185	173	239	egcg	egcg	NOUN
dti-2185	173	240	(	(	PUNCT
dti-2185	173	241	5	5	NUM
dti-2185	173	242	μm	μm	NOUN
dti-2185	173	243	)	)	PUNCT
dti-2185	173	244	human	human	ADJ
dti-2185	173	245	prostate	prostate	NOUN
dti-2185	173	246	cancer	cancer	NOUN
dti-2185	173	247	cells	cell	NOUN
dti-2185	173	248	inhibited	inhibit	VERB
dti-2185	173	249	diic16	diic16	NOUN
dti-2185	173	250	accumulation	accumulation	NOUN
dti-2185	173	251	in	in	ADP
dti-2185	173	252	lipid	lipid	NOUN
dti-2185	173	253	ordered	order	VERB
dti-2185	173	254	domains	domain	NOUN
dti-2185	173	255	and	and	CCONJ
dti-2185	173	256	disrupted	disrupt	VERB
dti-2185	173	257	lipid	lipid	NOUN
dti-2185	173	258	rafts	raft	NOUN
dti-2185	173	259	90	90	NUM
dti-2185	173	260	flavonoid	flavonoid	NOUN
dti-2185	173	261	egcg	egcg	NOUN
dti-2185	173	262	(	(	PUNCT
dti-2185	173	263	5	5	NUM
dti-2185	173	264	-	-	SYM
dti-2185	173	265	20	20	NUM
dti-2185	173	266	μm	μm	NUM
dti-2185	173	267	)	)	PUNCT
dti-2185	173	268	human	human	ADJ
dti-2185	173	269	multiple	multiple	ADJ
dti-2185	173	270	myeloma	myeloma	NOUN
dti-2185	173	271	cells	cell	NOUN
dti-2185	173	272	induced	induce	VERB
dti-2185	173	273	lipid	lipid	NOUN
dti-2185	173	274	raft	raft	NOUN
dti-2185	173	275	clustering	clustering	NOUN
dti-2185	173	276	and	and	CCONJ
dti-2185	173	277	apoptotic	apoptotic	ADJ
dti-2185	173	278	cell	cell	NOUN
dti-2185	173	279	death	death	NOUN
dti-2185	173	280	91	91	NUM
dti-2185	173	281	flavonoid	flavonoid	NOUN
dti-2185	173	282	dimeric	dimeric	ADJ
dti-2185	173	283	procyanidin	procyanidin	NOUN
dti-2185	173	284	(	(	PUNCT
dti-2185	173	285	0.05	0.05	NUM
dti-2185	173	286	-	-	SYM
dti-2185	173	287	1	1	NUM
dti-2185	173	288	μg	μg	NOUN
dti-2185	173	289	/	/	SYM
dti-2185	173	290	ml	ml	NOUN
dti-2185	173	291	)	)	PUNCT
dti-2185	173	292	human	human	ADJ
dti-2185	173	293	acute	acute	NOUN
dti-2185	173	294	t	t	PROPN
dti-2185	173	295	-	-	PUNCT
dti-2185	173	296	cell	cell	NOUN
dti-2185	173	297	leukemia	leukemia	NOUN
dti-2185	173	298	cells	cell	NOUN
dti-2185	173	299	increased	increase	VERB
dti-2185	173	300	the	the	DET
dti-2185	173	301	membrane	membrane	NOUN
dti-2185	173	302	fluidity	fluidity	NOUN
dti-2185	173	303	92	92	NUM
dti-2185	173	304	flavonoid	flavonoid	NOUN
dti-2185	173	305	hexameric	hexameric	NOUN
dti-2185	173	306	procyanidin	procyanidin	PROPN
dti-2185	173	307	(	(	PUNCT
dti-2185	173	308	10	10	NUM
dti-2185	173	309	μm	μm	NOUN
dti-2185	173	310	)	)	PUNCT
dti-2185	173	311	human	human	ADJ
dti-2185	173	312	colon	colon	NOUN
dti-2185	173	313	cancer	cancer	NOUN
dti-2185	173	314	cells	cell	NOUN
dti-2185	173	315	decreased	decrease	VERB
dti-2185	173	316	the	the	DET
dti-2185	173	317	membrane	membrane	NOUN
dti-2185	173	318	fluidity	fluidity	NOUN
dti-2185	173	319	,	,	PUNCT
dti-2185	173	320	although	although	SCONJ
dti-2185	173	321	the	the	DET
dti-2185	173	322	membrane	membrane	NOUN
dti-2185	173	323	interactivity	interactivity	NOUN
dti-2185	173	324	was	be	AUX
dti-2185	173	325	lost	lose	VERB
dti-2185	173	326	by	by	ADP
dti-2185	173	327	mbc	mbc	PROPN
dti-2185	173	328	(	(	PUNCT
dti-2185	173	329	2.5	2.5	NUM
dti-2185	173	330	mm	mm	NOUN
dti-2185	173	331	)	)	PUNCT
dti-2185	173	332	prevented	prevent	VERB
dti-2185	173	333	the	the	DET
dti-2185	173	334	lipid	lipid	NOUN
dti-2185	173	335	raft	raft	NOUN
dti-2185	173	336	disruption	disruption	NOUN
dti-2185	173	337	induced	induce	VERB
dti-2185	173	338	by	by	ADP
dti-2185	173	339	mbc	mbc	PROPN
dti-2185	173	340	or	or	CCONJ
dti-2185	173	341	deoxycholate	deoxycholate	VERB
dti-2185	173	342	93	93	NUM
dti-2185	173	343	stilbenoid	stilbenoid	ADJ
dti-2185	173	344	resveratrol	resveratrol	NOUN
dti-2185	173	345	(	(	PUNCT
dti-2185	173	346	10	10	NUM
dti-2185	173	347	-	-	SYM
dti-2185	173	348	80	80	NUM
dti-2185	173	349	μm	μm	NUM
dti-2185	173	350	)	)	PUNCT
dti-2185	173	351	luvs	luvs	NOUN
dti-2185	173	352	(	(	PUNCT
dti-2185	173	353	egg	egg	NOUN
dti-2185	173	354	phosphatidylcholine	phosphatidylcholine	NOUN
dti-2185	173	355	,	,	PUNCT
dti-2185	173	356	sm	sm	PROPN
dti-2185	173	357	and	and	CCONJ
dti-2185	173	358	cholesterol	cholesterol	PROPN
dti-2185	173	359	,	,	PUNCT
dti-2185	173	360	1:1:1	1:1:1	PROPN
dti-2185	173	361	molar	molar	ADJ
dti-2185	173	362	ratio	ratio	NOUN
dti-2185	173	363	)	)	PUNCT
dti-2185	173	364	formed	form	VERB
dti-2185	173	365	the	the	DET
dti-2185	173	366	ordered	order	VERB
dti-2185	173	367	membrane	membrane	NOUN
dti-2185	173	368	domains	domain	NOUN
dti-2185	173	369	and	and	CCONJ
dti-2185	173	370	enhanced	enhance	VERB
dti-2185	173	371	the	the	DET
dti-2185	173	372	membrane	membrane	NOUN
dti-2185	173	373	resistance	resistance	NOUN
dti-2185	173	374	to	to	ADP
dti-2185	173	375	triton	triton	PROPN
dti-2185	173	376	x-100	x-100	PROPN
dti-2185	173	377	94	94	NUM
dti-2185	173	378	anthraquinonoid	anthraquinonoid	NOUN
dti-2185	173	379	emodin	emodin	VERB
dti-2185	173	380	(	(	PUNCT
dti-2185	173	381	1	1	NUM
dti-2185	173	382	-	-	SYM
dti-2185	173	383	5	5	NUM
dti-2185	173	384	mol%	mol%	NOUN
dti-2185	173	385	)	)	PUNCT
dti-2185	173	386	aloin	aloin	NOUN
dti-2185	173	387	(	(	PUNCT
dti-2185	173	388	1	1	NUM
dti-2185	173	389	-	-	SYM
dti-2185	173	390	5	5	NUM
dti-2185	173	391	mol%	mol%	NOUN
dti-2185	173	392	)	)	PUNCT
dti-2185	173	393	mlvs	mlv	NOUN
dti-2185	173	394	composed	compose	VERB
dti-2185	173	395	of	of	ADP
dti-2185	173	396	dmpc	dmpc	NOUN
dti-2185	173	397	reduced	reduce	VERB
dti-2185	173	398	the	the	DET
dti-2185	173	399	phase	phase	NOUN
dti-2185	173	400	transition	transition	NOUN
dti-2185	173	401	temperature	temperature	NOUN
dti-2185	173	402	95	95	NUM
dti-2185	173	403	anthraquinonoid	anthraquinonoid	NOUN
dti-2185	173	404	emodin	emodin	VERB
dti-2185	173	405	(	(	PUNCT
dti-2185	173	406	10	10	NUM
dti-2185	173	407	-	-	SYM
dti-2185	173	408	50	50	NUM
dti-2185	173	409	μg	μg	NOUN
dti-2185	173	410	/	/	SYM
dti-2185	173	411	ml	ml	NOUN
dti-2185	173	412	)	)	PUNCT
dti-2185	173	413	human	human	ADJ
dti-2185	173	414	umbilical	umbilical	ADJ
dti-2185	173	415	vein	vein	ADJ
dti-2185	173	416	endothelial	endothelial	NOUN
dti-2185	173	417	cells	cell	NOUN
dti-2185	173	418	disrupted	disrupt	VERB
dti-2185	173	419	lipid	lipid	NOUN
dti-2185	173	420	rafts	raft	NOUN
dti-2185	173	421	96	96	NUM
dti-2185	173	422	terpenoid	terpenoid	PROPN
dti-2185	173	423	ginsenosides	ginsenoside	NOUN
dti-2185	173	424	rb2	rb2	PROPN
dti-2185	173	425	,	,	PUNCT
dti-2185	173	426	rc	rc	PROPN
dti-2185	173	427	,	,	PUNCT
dti-2185	173	428	rd	rd	PROPN
dti-2185	173	429	,	,	PUNCT
dti-2185	173	430	re	re	ADP
dti-2185	173	431	,	,	PUNCT
dti-2185	173	432	rf	rf	PROPN
dti-2185	173	433	,	,	PUNCT
dti-2185	173	434	rg1	rg1	PROPN
dti-2185	173	435	,	,	PUNCT
dti-2185	173	436	rg2	rg2	NOUN
dti-2185	173	437	and	and	CCONJ
dti-2185	173	438	rh2	rh2	X
dti-2185	173	439	(	(	PUNCT
dti-2185	173	440	50	50	NUM
dti-2185	173	441	μm	μm	NOUN
dti-2185	173	442	)	)	PUNCT
dti-2185	174	1	hela	hela	PROPN
dti-2185	174	2	cells	cell	NOUN
dti-2185	174	3	increased	increase	VERB
dti-2185	174	4	the	the	DET
dti-2185	174	5	membrane	membrane	NOUN
dti-2185	174	6	fluidity	fluidity	NOUN
dti-2185	174	7	reduced	reduce	VERB
dti-2185	174	8	the	the	DET
dti-2185	174	9	raft	raft	NOUN
dti-2185	174	10	-	-	PUNCT
dti-2185	174	11	marker	marker	NOUN
dti-2185	174	12	protein	protein	NOUN
dti-2185	174	13	concentration	concentration	NOUN
dti-2185	174	14	in	in	ADP
dti-2185	174	15	lipid	lipid	ADJ
dti-2185	174	16	rafts	raft	NOUN
dti-2185	174	17	98	98	NUM
dti-2185	174	18	terpenoid	terpenoid	PROPN
dti-2185	174	19	saikosaponin	saikosaponin	NOUN
dti-2185	174	20	a	a	DET
dti-2185	174	21	(	(	PUNCT
dti-2185	174	22	3	3	NUM
dti-2185	174	23	-	-	SYM
dti-2185	174	24	12	12	NUM
dti-2185	174	25	μm	μm	NOUN
dti-2185	174	26	)	)	PUNCT
dti-2185	174	27	mouse	mouse	NOUN
dti-2185	174	28	macrophages	macrophage	NOUN
dti-2185	174	29	inhibited	inhibit	VERB
dti-2185	174	30	lps	lps	PROPN
dti-2185	174	31	-	-	PUNCT
dti-2185	174	32	induced	induce	VERB
dti-2185	174	33	cytokine	cytokine	ADJ
dti-2185	174	34	expression	expression	NOUN
dti-2185	174	35	and	and	CCONJ
dti-2185	174	36	toll	toll	NOUN
dti-2185	174	37	-	-	PUNCT
dti-2185	174	38	like	like	ADJ
dti-2185	174	39	receptor	receptor	NOUN
dti-2185	174	40	localization	localization	NOUN
dti-2185	174	41	in	in	ADP
dti-2185	174	42	lipid	lipid	ADJ
dti-2185	174	43	rafts	raft	NOUN
dti-2185	174	44	,	,	PUNCT
dti-2185	174	45	and	and	CCONJ
dti-2185	174	46	reduced	reduce	VERB
dti-2185	174	47	membrane	membrane	NOUN
dti-2185	174	48	cholesterol	cholesterol	NOUN
dti-2185	174	49	levels	level	NOUN
dti-2185	174	50	99	99	NUM
dti-2185	174	51	dmpc	dmpc	NOUN
dti-2185	174	52	=	=	SYM
dti-2185	174	53	1,2	1,2	NUM
dti-2185	174	54	-	-	PUNCT
dti-2185	174	55	dimyristoylphosphatidylcholine	dimyristoylphosphatidylcholine	NOUN
dti-2185	174	56	;	;	PUNCT
dti-2185	174	57	dopc	dopc	NOUN
dti-2185	174	58	=	=	SYM
dti-2185	174	59	1,2	1,2	NUM
dti-2185	174	60	-	-	PUNCT
dti-2185	174	61	dioleoylphosphatidylcholine	dioleoylphosphatidylcholine	NOUN
dti-2185	174	62	;	;	PUNCT
dti-2185	174	63	egcg	egcg	NOUN
dti-2185	174	64	=	=	SYM
dti-2185	174	65	(	(	PUNCT
dti-2185	174	66	–	–	PUNCT
dti-2185	174	67	)	)	PUNCT
dti-2185	174	68	-epigallocatechin-3	-epigallocatechin-3	NOUN
dti-2185	174	69	-	-	PUNCT
dti-2185	174	70	gallate	gallate	NOUN
dti-2185	174	71	;	;	PUNCT
dti-2185	175	1	lps	lps	PROPN
dti-2185	175	2	=	=	PUNCT
dti-2185	175	3	lipopolysaccharide	lipopolysaccharide	ADJ
dti-2185	175	4	;	;	PUNCT
dti-2185	175	5	luv	luv	NOUN
dti-2185	175	6	=	=	PROPN
dti-2185	175	7	large	large	ADJ
dti-2185	175	8	unilamellar	unilamellar	ADJ
dti-2185	175	9	vesicle	vesicle	NOUN
dti-2185	175	10	;	;	PUNCT
dti-2185	175	11	mbc	mbc	PROPN
dti-2185	175	12	=	=	SYM
dti-2185	175	13	methyl	methyl	NOUN
dti-2185	175	14	-	-	PUNCT
dti-2185	175	15	β	β	NOUN
dti-2185	175	16	-	-	NOUN
dti-2185	175	17	cyclodextrin	cyclodextrin	NOUN
dti-2185	175	18	;	;	PUNCT
dti-2185	175	19	mlv	mlv	ADJ
dti-2185	175	20	=	=	SYM
dti-2185	175	21	multilamellar	multilamellar	ADJ
dti-2185	175	22	vesicle	vesicle	NOUN
dti-2185	175	23	;	;	PUNCT
dti-2185	175	24	popc	popc	NOUN
dti-2185	175	25	=	=	SYM
dti-2185	175	26	1	1	NUM
dti-2185	175	27	-	-	PUNCT
dti-2185	175	28	palmitoyl-2	palmitoyl-2	VERB
dti-2185	175	29	-	-	PUNCT
dti-2185	175	30	oleoylphosphatidylcholine	oleoylphosphatidylcholine	NOUN
dti-2185	175	31	;	;	PUNCT
dti-2185	175	32	sm	sm	PROPN
dti-2185	175	33	=	=	SYM
dti-2185	175	34	sphingomyelin	sphingomyelin	NOUN
dti-2185	175	35	;	;	PUNCT
dti-2185	175	36	suv	suv	X
dti-2185	175	37	=	=	SYM
dti-2185	175	38	small	small	ADJ
dti-2185	175	39	unilamellar	unilamellar	ADJ
dti-2185	175	40	vesicle	vesicle	NOUN
dti-2185	175	41	;	;	PUNCT
dti-2185	175	42	tnf	tnf	PROPN
dti-2185	175	43	=	=	PUNCT
dti-2185	175	44	tumor	tumor	NOUN
dti-2185	175	45	necrosis	necrosis	NOUN
dti-2185	175	46	factor	factor	NOUN
dti-2185	175	47	;	;	PUNCT
dti-2185	175	48	trail	trail	NOUN
dti-2185	175	49	=	=	SYM
dti-2185	175	50	tnf	tnf	PROPN
dti-2185	175	51	-	-	PUNCT
dti-2185	175	52	related	relate	VERB
dti-2185	175	53	apoptosis	apoptosis	NOUN
dti-2185	175	54	-	-	PUNCT
dti-2185	175	55	inducing	induce	VERB
dti-2185	175	56	ligand	ligand	NOUN
dti-2185	175	57	.	.	PUNCT
dti-2185	176	1	tsuchiya	tsuchiya	PROPN
dti-2185	176	2	and	and	CCONJ
dti-2185	176	3	mizogami	mizogami	PROPN
dti-2185	176	4	43	43	NUM
dti-2185	176	5	©	©	PROPN
dti-2185	176	6	2020	2020	NUM
dti-2185	176	7	the	the	DET
dti-2185	176	8	authors	author	NOUN
dti-2185	176	9	.	.	PUNCT
dti-2185	177	1	published	publish	VERB
dti-2185	177	2	by	by	ADP
dti-2185	177	3	aboutscience	aboutscience	NOUN
dti-2185	177	4	flavonoids	flavonoid	NOUN
dti-2185	177	5	considering	consider	VERB
dti-2185	177	6	the	the	DET
dti-2185	177	7	distribution	distribution	NOUN
dti-2185	177	8	and	and	CCONJ
dti-2185	177	9	accumulation	accumulation	NOUN
dti-2185	177	10	in	in	ADP
dti-2185	177	11	lipid	lipid	ADJ
dti-2185	177	12	bilayers	bilayer	NOUN
dti-2185	177	13	,	,	PUNCT
dti-2185	177	14	representative	representative	ADJ
dti-2185	177	15	flavonoid	flavonoid	NOUN
dti-2185	177	16	quercetin	quercetin	NOUN
dti-2185	177	17	and	and	CCONJ
dti-2185	177	18	(	(	PUNCT
dti-2185	177	19	–	–	PUNCT
dti-2185	177	20	)	)	PUNCT
dti-2185	177	21	-epigallocatechin-3	-epigallocatechin-3	NOUN
dti-2185	177	22	-	-	PUNCT
dti-2185	177	23	gallate	gallate	NOUN
dti-2185	177	24	(	(	PUNCT
dti-2185	177	25	egcg	egcg	NOUN
dti-2185	177	26	)	)	PUNCT
dti-2185	177	27	possibly	possibly	ADV
dti-2185	177	28	alter	alter	VERB
dti-2185	177	29	membrane	membrane	NOUN
dti-2185	177	30	fluidity	fluidity	NOUN
dti-2185	177	31	and	and	CCONJ
dti-2185	177	32	order	order	NOUN
dti-2185	177	33	,	,	PUNCT
dti-2185	177	34	making	make	VERB
dti-2185	177	35	or	or	CCONJ
dti-2185	177	36	breaking	break	VERB
dti-2185	177	37	raft	raft	NOUN
dti-2185	177	38	-	-	PUNCT
dti-2185	177	39	like	like	ADJ
dti-2185	177	40	domains	domain	NOUN
dti-2185	177	41	(	(	PUNCT
dti-2185	177	42	83	83	NUM
dti-2185	177	43	)	)	PUNCT
dti-2185	177	44	.	.	PUNCT
dti-2185	178	1	tsuchiya	tsuchiya	PROPN
dti-2185	178	2	and	and	CCONJ
dti-2185	178	3	mizogami	mizogami	PROPN
dti-2185	178	4	compared	compare	VERB
dti-2185	178	5	the	the	DET
dti-2185	178	6	effects	effect	NOUN
dti-2185	178	7	of	of	ADP
dti-2185	178	8	different	different	ADJ
dti-2185	178	9	flavonoids	flavonoid	NOUN
dti-2185	178	10	on	on	ADP
dti-2185	178	11	suvs	suvs	NOUN
dti-2185	178	12	that	that	PRON
dti-2185	178	13	were	be	AUX
dti-2185	178	14	prepared	prepare	VERB
dti-2185	178	15	with	with	ADP
dti-2185	178	16	phospholipids	phospholipid	NOUN
dti-2185	178	17	(	(	PUNCT
dti-2185	178	18	popc	popc	NOUN
dti-2185	178	19	and	and	CCONJ
dti-2185	178	20	sm	sm	NOUN
dti-2185	178	21	)	)	PUNCT
dti-2185	178	22	and	and	CCONJ
dti-2185	178	23	cholesterol	cholesterol	NOUN
dti-2185	178	24	by	by	ADP
dti-2185	178	25	varying	vary	VERB
dti-2185	178	26	their	their	PRON
dti-2185	178	27	compositions	composition	NOUN
dti-2185	178	28	55	55	NUM
dti-2185	178	29	-	-	SYM
dti-2185	178	30	80	80	NUM
dti-2185	178	31	mol%	mol%	NOUN
dti-2185	178	32	and	and	CCONJ
dti-2185	178	33	20	20	NUM
dti-2185	178	34	-	-	SYM
dti-2185	178	35	45	45	NUM
dti-2185	178	36	mol%	mol%	NOUN
dti-2185	178	37	,	,	PUNCT
dti-2185	178	38	respectively	respectively	ADV
dti-2185	178	39	(	(	PUNCT
dti-2185	178	40	84	84	NUM
dti-2185	178	41	)	)	PUNCT
dti-2185	178	42	.	.	PUNCT
dti-2185	179	1	fp	fp	PROPN
dti-2185	179	2	data	datum	NOUN
dti-2185	179	3	indicated	indicate	VERB
dti-2185	179	4	that	that	SCONJ
dti-2185	179	5	quercetin	quercetin	NOUN
dti-2185	179	6	interacts	interact	VERB
dti-2185	179	7	preferentially	preferentially	ADV
dti-2185	179	8	with	with	ADP
dti-2185	179	9	the	the	DET
dti-2185	179	10	hydrophobic	hydrophobic	NOUN
dti-2185	179	11	region	region	NOUN
dti-2185	179	12	of	of	ADP
dti-2185	179	13	membranes	membrane	NOUN
dti-2185	179	14	to	to	PART
dti-2185	179	15	decrease	decrease	VERB
dti-2185	179	16	the	the	DET
dti-2185	179	17	fluidity	fluidity	NOUN
dti-2185	179	18	at	at	ADP
dti-2185	179	19	10	10	NUM
dti-2185	179	20	μm	μm	NOUN
dti-2185	179	21	most	most	ADV
dti-2185	179	22	potently	potently	ADV
dti-2185	179	23	,	,	PUNCT
dti-2185	179	24	followed	follow	VERB
dti-2185	179	25	by	by	ADP
dti-2185	179	26	cyanidin	cyanidin	VERB
dti-2185	179	27	and	and	CCONJ
dti-2185	179	28	egcg	egcg	NOUN
dti-2185	179	29	.	.	PUNCT
dti-2185	180	1	psahoulia	psahoulia	PROPN
dti-2185	180	2	et	et	PROPN
dti-2185	180	3	al	al	PROPN
dti-2185	180	4	investigated	investigate	VERB
dti-2185	180	5	the	the	DET
dti-2185	180	6	mechanism	mechanism	NOUN
dti-2185	180	7	underlying	underlie	VERB
dti-2185	180	8	an	an	DET
dti-2185	180	9	apoptosis	apoptosis	NOUN
dti-2185	180	10	enhancing	enhance	VERB
dti-2185	180	11	effect	effect	NOUN
dti-2185	180	12	of	of	ADP
dti-2185	180	13	quercetin	quercetin	NOUN
dti-2185	180	14	by	by	ADP
dti-2185	180	15	treating	treat	VERB
dti-2185	180	16	human	human	ADJ
dti-2185	180	17	colon	colon	NOUN
dti-2185	180	18	cancer	cancer	NOUN
dti-2185	180	19	cells	cell	NOUN
dti-2185	180	20	(	(	PUNCT
dti-2185	180	21	ht-29	ht-29	X
dti-2185	180	22	,	,	PUNCT
dti-2185	180	23	sw-620	sw-620	NOUN
dti-2185	180	24	and	and	CCONJ
dti-2185	180	25	caco-2	caco-2	NOUN
dti-2185	180	26	)	)	PUNCT
dti-2185	180	27	with	with	ADP
dti-2185	180	28	quercetin	quercetin	NOUN
dti-2185	180	29	at	at	ADP
dti-2185	180	30	30	30	NUM
dti-2185	180	31	μm	μm	NOUN
dti-2185	180	32	(	(	PUNCT
dti-2185	180	33	85	85	NUM
dti-2185	180	34	)	)	PUNCT
dti-2185	180	35	.	.	PUNCT
dti-2185	181	1	while	while	SCONJ
dti-2185	181	2	tumor	tumor	NOUN
dti-2185	181	3	necrosis	necrosis	NOUN
dti-2185	181	4	factor	factor	NOUN
dti-2185	181	5	(	(	PUNCT
dti-2185	181	6	tnf)-related	tnf)-relate	VERB
dti-2185	181	7	apoptosisinducing	apoptosisinducing	NOUN
dti-2185	181	8	ligand	ligand	NOUN
dti-2185	181	9	(	(	PUNCT
dti-2185	181	10	trail	trail	NOUN
dti-2185	181	11	)	)	PUNCT
dti-2185	181	12	contributes	contribute	VERB
dti-2185	181	13	to	to	ADP
dti-2185	181	14	apoptosis	apoptosis	NOUN
dti-2185	181	15	induction	induction	NOUN
dti-2185	181	16	,	,	PUNCT
dti-2185	181	17	quercetin	quercetin	NOUN
dti-2185	181	18	enhanced	enhance	VERB
dti-2185	181	19	the	the	DET
dti-2185	181	20	trail	trail	NOUN
dti-2185	181	21	efficacy	efficacy	NOUN
dti-2185	181	22	to	to	PART
dti-2185	181	23	induce	induce	VERB
dti-2185	181	24	apoptosis	apoptosis	NOUN
dti-2185	181	25	by	by	ADP
dti-2185	181	26	accumulating	accumulate	VERB
dti-2185	181	27	death	death	NOUN
dti-2185	181	28	receptors	receptor	NOUN
dti-2185	181	29	in	in	ADP
dti-2185	181	30	membrane	membrane	NOUN
dti-2185	181	31	lipid	lipid	NOUN
dti-2185	181	32	rafts	raft	NOUN
dti-2185	181	33	.	.	PUNCT
dti-2185	182	1	in	in	ADP
dti-2185	182	2	a	a	DET
dti-2185	182	3	cell	cell	NOUN
dti-2185	182	4	culture	culture	NOUN
dti-2185	182	5	study	study	NOUN
dti-2185	182	6	of	of	ADP
dti-2185	182	7	kaneko	kaneko	PROPN
dti-2185	182	8	et	et	PROPN
dti-2185	182	9	al	al	PROPN
dti-2185	182	10	,	,	PUNCT
dti-2185	182	11	quercetin	quercetin	NOUN
dti-2185	182	12	and	and	CCONJ
dti-2185	182	13	luteolin	luteolin	PROPN
dti-2185	182	14	suppressed	suppress	VERB
dti-2185	182	15	the	the	DET
dti-2185	182	16	accumulation	accumulation	NOUN
dti-2185	182	17	of	of	ADP
dti-2185	182	18	lipid	lipid	ADJ
dti-2185	182	19	rafts	raft	NOUN
dti-2185	182	20	at	at	ADP
dti-2185	182	21	10	10	NUM
dti-2185	182	22	and	and	CCONJ
dti-2185	182	23	100	100	NUM
dti-2185	182	24	μm	μm	NOUN
dti-2185	182	25	to	to	PART
dti-2185	182	26	inhibit	inhibit	VERB
dti-2185	182	27	tnf	tnf	PROPN
dti-2185	182	28	-	-	PUNCT
dti-2185	182	29	α	α	PROPN
dti-2185	182	30	production	production	NOUN
dti-2185	182	31	in	in	ADP
dti-2185	182	32	mouse	mouse	NOUN
dti-2185	182	33	macrophages	macrophage	NOUN
dti-2185	182	34	(	(	PUNCT
dti-2185	182	35	86	86	NUM
dti-2185	182	36	)	)	PUNCT
dti-2185	182	37	.	.	PUNCT
dti-2185	183	1	they	they	PRON
dti-2185	183	2	also	also	ADV
dti-2185	183	3	suggested	suggest	VERB
dti-2185	183	4	that	that	SCONJ
dti-2185	183	5	these	these	DET
dti-2185	183	6	flavonoids	flavonoid	NOUN
dti-2185	183	7	change	change	VERB
dti-2185	183	8	membrane	membrane	ADJ
dti-2185	183	9	fluidity	fluidity	NOUN
dti-2185	183	10	.	.	PUNCT
dti-2185	184	1	ionescu	ionescu	PROPN
dti-2185	184	2	et	et	PROPN
dti-2185	184	3	al	al	PROPN
dti-2185	184	4	prepared	prepare	VERB
dti-2185	184	5	suvs	suvs	NOUN
dti-2185	184	6	with	with	ADP
dti-2185	184	7	dmpc	dmpc	NOUN
dti-2185	184	8	plus	plus	CCONJ
dti-2185	184	9	20	20	NUM
dti-2185	184	10	or	or	CCONJ
dti-2185	184	11	33	33	NUM
dti-2185	184	12	mol%	mol%	PROPN
dti-2185	184	13	cholesterol	cholesterol	NOUN
dti-2185	184	14	to	to	PART
dti-2185	184	15	form	form	VERB
dti-2185	184	16	the	the	DET
dti-2185	184	17	lo	lo	PROPN
dti-2185	184	18	phase	phase	NOUN
dti-2185	184	19	and	and	CCONJ
dti-2185	184	20	examine	examine	VERB
dti-2185	184	21	the	the	DET
dti-2185	184	22	membrane	membrane	NOUN
dti-2185	184	23	effect	effect	NOUN
dti-2185	184	24	of	of	ADP
dti-2185	184	25	quercetin	quercetin	NOUN
dti-2185	184	26	(	(	PUNCT
dti-2185	184	27	87	87	NUM
dti-2185	184	28	)	)	PUNCT
dti-2185	184	29	.	.	PUNCT
dti-2185	185	1	fp	fp	PROPN
dti-2185	185	2	measurements	measurement	NOUN
dti-2185	185	3	showed	show	VERB
dti-2185	185	4	that	that	SCONJ
dti-2185	185	5	quercetin	quercetin	NOUN
dti-2185	185	6	increases	increase	VERB
dti-2185	185	7	the	the	DET
dti-2185	185	8	fluidity	fluidity	NOUN
dti-2185	185	9	of	of	ADP
dti-2185	185	10	raft	raft	NOUN
dti-2185	185	11	model	model	NOUN
dti-2185	185	12	membranes	membrane	NOUN
dti-2185	185	13	at	at	ADP
dti-2185	185	14	2	2	NUM
dti-2185	185	15	-	-	SYM
dti-2185	185	16	16	16	NUM
dti-2185	185	17	μm	μm	NOUN
dti-2185	185	18	.	.	PUNCT
dti-2185	186	1	tsuchiya	tsuchiya	PROPN
dti-2185	186	2	treated	treat	VERB
dti-2185	186	3	suvs	suvs	NOUN
dti-2185	186	4	consisting	consisting	NOUN
dti-2185	186	5	of	of	ADP
dti-2185	186	6	5	5	NUM
dti-2185	186	7	mol%	mol%	PROPN
dti-2185	186	8	cholesterol	cholesterol	NOUN
dti-2185	186	9	and	and	CCONJ
dti-2185	186	10	95	95	NUM
dti-2185	186	11	mol%	mol%	PROPN
dti-2185	186	12	popc	popc	NOUN
dti-2185	186	13	or	or	CCONJ
dti-2185	186	14	dopc	dopc	NOUN
dti-2185	186	15	with	with	ADP
dti-2185	186	16	several	several	ADJ
dti-2185	186	17	catechins	catechin	NOUN
dti-2185	186	18	,	,	PUNCT
dti-2185	186	19	followed	follow	VERB
dti-2185	186	20	by	by	ADP
dti-2185	186	21	fp	fp	NOUN
dti-2185	186	22	measurements	measurement	NOUN
dti-2185	186	23	(	(	PUNCT
dti-2185	186	24	88	88	NUM
dti-2185	186	25	)	)	PUNCT
dti-2185	186	26	.	.	PUNCT
dti-2185	187	1	of	of	ADP
dti-2185	187	2	the	the	DET
dti-2185	187	3	tested	test	VERB
dti-2185	187	4	catechins	catechin	NOUN
dti-2185	187	5	,	,	PUNCT
dti-2185	187	6	egcg	egcg	NOUN
dti-2185	187	7	most	most	ADV
dti-2185	187	8	potently	potently	ADV
dti-2185	187	9	interacted	interact	VERB
dti-2185	187	10	with	with	ADP
dti-2185	187	11	binary	binary	ADJ
dti-2185	187	12	membranes	membrane	NOUN
dti-2185	187	13	to	to	PART
dti-2185	187	14	decrease	decrease	VERB
dti-2185	187	15	their	their	PRON
dti-2185	187	16	fluidity	fluidity	NOUN
dti-2185	187	17	at	at	ADP
dti-2185	187	18	5	5	NUM
dti-2185	187	19	-	-	SYM
dti-2185	187	20	100	100	NUM
dti-2185	187	21	μm	μm	NOUN
dti-2185	187	22	.	.	PUNCT
dti-2185	188	1	adachi	adachi	PROPN
dti-2185	188	2	et	et	PROPN
dti-2185	188	3	al	al	PROPN
dti-2185	188	4	stained	stain	VERB
dti-2185	188	5	human	human	ADJ
dti-2185	188	6	colon	colon	NOUN
dti-2185	188	7	carcinoma	carcinoma	NOUN
dti-2185	188	8	(	(	PUNCT
dti-2185	188	9	ht29	ht29	PROPN
dti-2185	188	10	)	)	PUNCT
dti-2185	188	11	cells	cell	NOUN
dti-2185	188	12	with	with	ADP
dti-2185	188	13	fluorescent	fluorescent	ADJ
dti-2185	188	14	diic16	diic16	NOUN
dti-2185	188	15	(	(	PUNCT
dti-2185	188	16	1,1’-dihexadecyl3,3,3’,3’-tetramethylindocarbocyanine	1,1’-dihexadecyl3,3,3’,3’-tetramethylindocarbocyanine	NUM
dti-2185	188	17	perchlorate	perchlorate	NOUN
dti-2185	188	18	)	)	PUNCT
dti-2185	188	19	that	that	PRON
dti-2185	188	20	is	be	AUX
dti-2185	188	21	preferentially	preferentially	ADV
dti-2185	188	22	incorporated	incorporate	VERB
dti-2185	188	23	into	into	ADP
dti-2185	188	24	the	the	DET
dti-2185	188	25	ordered	order	VERB
dti-2185	188	26	membranes	membrane	NOUN
dti-2185	188	27	,	,	PUNCT
dti-2185	188	28	and	and	CCONJ
dti-2185	188	29	then	then	ADV
dti-2185	188	30	treated	treat	VERB
dti-2185	188	31	the	the	DET
dti-2185	188	32	cells	cell	NOUN
dti-2185	188	33	with	with	ADP
dti-2185	188	34	egcg	egcg	NOUN
dti-2185	188	35	at	at	ADP
dti-2185	188	36	5	5	NUM
dti-2185	188	37	-	-	SYM
dti-2185	188	38	20	20	NUM
dti-2185	188	39	μg	μg	NOUN
dti-2185	188	40	/	/	SYM
dti-2185	188	41	ml	ml	NOUN
dti-2185	188	42	to	to	PART
dti-2185	188	43	analyze	analyze	VERB
dti-2185	188	44	its	its	PRON
dti-2185	188	45	membrane	membrane	NOUN
dti-2185	188	46	effects	effect	NOUN
dti-2185	188	47	by	by	ADP
dti-2185	188	48	fluorescent	fluorescent	ADJ
dti-2185	188	49	confocal	confocal	ADJ
dti-2185	188	50	microscopy	microscopy	NOUN
dti-2185	188	51	(	(	PUNCT
dti-2185	188	52	89	89	NUM
dti-2185	188	53	)	)	PUNCT
dti-2185	188	54	.	.	PUNCT
dti-2185	189	1	egcg	egcg	NOUN
dti-2185	189	2	reduced	reduce	VERB
dti-2185	189	3	the	the	DET
dti-2185	189	4	membrane	membrane	NOUN
dti-2185	189	5	resistance	resistance	NOUN
dti-2185	189	6	to	to	ADP
dti-2185	189	7	triton	triton	PROPN
dti-2185	189	8	x-100	x-100	PROPN
dti-2185	190	1	at	at	ADP
dti-2185	190	2	as	as	ADV
dti-2185	190	3	little	little	ADJ
dti-2185	190	4	as	as	ADP
dti-2185	190	5	5	5	NUM
dti-2185	190	6	μg	μg	NOUN
dti-2185	190	7	/	/	SYM
dti-2185	190	8	ml	ml	PROPN
dti-2185	190	9	,	,	PUNCT
dti-2185	190	10	possibly	possibly	ADV
dti-2185	190	11	by	by	ADP
dti-2185	190	12	decreasing	decrease	VERB
dti-2185	190	13	the	the	DET
dti-2185	190	14	content	content	NOUN
dti-2185	190	15	of	of	ADP
dti-2185	190	16	ordered	order	VERB
dti-2185	190	17	membrane	membrane	NOUN
dti-2185	190	18	domains	domain	NOUN
dti-2185	190	19	.	.	PUNCT
dti-2185	191	1	duhon	duhon	PROPN
dti-2185	191	2	et	et	PROPN
dti-2185	191	3	al	al	PROPN
dti-2185	191	4	exposed	expose	VERB
dti-2185	191	5	human	human	ADJ
dti-2185	191	6	prostate	prostate	NOUN
dti-2185	191	7	cancer	cancer	NOUN
dti-2185	191	8	(	(	PUNCT
dti-2185	191	9	du145	du145	NOUN
dti-2185	191	10	)	)	PUNCT
dti-2185	191	11	cells	cell	NOUN
dti-2185	191	12	to	to	ADP
dti-2185	191	13	diic16	diic16	NOUN
dti-2185	191	14	in	in	ADP
dti-2185	191	15	the	the	DET
dti-2185	191	16	presence	presence	NOUN
dti-2185	191	17	or	or	CCONJ
dti-2185	191	18	absence	absence	NOUN
dti-2185	191	19	of	of	ADP
dti-2185	191	20	5	5	NUM
dti-2185	191	21	μm	μm	NOUN
dti-2185	191	22	egcg	egcg	NOUN
dti-2185	191	23	,	,	PUNCT
dti-2185	191	24	followed	follow	VERB
dti-2185	191	25	by	by	ADP
dti-2185	191	26	fluorescence	fluorescence	NOUN
dti-2185	191	27	microscopic	microscopic	ADJ
dti-2185	191	28	analysis	analysis	NOUN
dti-2185	191	29	(	(	PUNCT
dti-2185	191	30	90	90	NUM
dti-2185	191	31	)	)	PUNCT
dti-2185	191	32	.	.	PUNCT
dti-2185	192	1	egcg	egcg	NOUN
dti-2185	192	2	inhibited	inhibit	VERB
dti-2185	192	3	the	the	DET
dti-2185	192	4	accumulation	accumulation	NOUN
dti-2185	192	5	of	of	ADP
dti-2185	192	6	diic16	diic16	NOUN
dti-2185	192	7	in	in	ADP
dti-2185	192	8	lipid	lipid	NOUN
dti-2185	192	9	-	-	PUNCT
dti-2185	192	10	ordered	order	VERB
dti-2185	192	11	domains	domain	NOUN
dti-2185	192	12	and	and	CCONJ
dti-2185	192	13	disrupted	disrupt	VERB
dti-2185	192	14	lipid	lipid	NOUN
dti-2185	192	15	rafts	raft	NOUN
dti-2185	192	16	.	.	PUNCT
dti-2185	193	1	tsukamoto	tsukamoto	NOUN
dti-2185	193	2	et	et	PROPN
dti-2185	193	3	al	al	PROPN
dti-2185	193	4	treated	treat	VERB
dti-2185	193	5	human	human	ADJ
dti-2185	193	6	multiple	multiple	ADJ
dti-2185	193	7	myeloma	myeloma	NOUN
dti-2185	193	8	(	(	PUNCT
dti-2185	193	9	u266	u266	PROPN
dti-2185	193	10	)	)	PUNCT
dti-2185	193	11	cells	cell	NOUN
dti-2185	193	12	with	with	ADP
dti-2185	193	13	egcg	egcg	NOUN
dti-2185	193	14	at	at	ADP
dti-2185	193	15	5	5	NUM
dti-2185	193	16	-	-	SYM
dti-2185	193	17	20	20	NUM
dti-2185	193	18	μm	μm	NOUN
dti-2185	193	19	for	for	ADP
dti-2185	193	20	3	3	NUM
dti-2185	193	21	hours	hour	NOUN
dti-2185	193	22	and	and	CCONJ
dti-2185	193	23	at	at	ADP
dti-2185	193	24	10	10	NUM
dti-2185	193	25	μm	μm	NOUN
dti-2185	193	26	for	for	ADP
dti-2185	193	27	1	1	NUM
dti-2185	193	28	-	-	SYM
dti-2185	193	29	3	3	NUM
dti-2185	193	30	hours	hour	NOUN
dti-2185	193	31	(	(	PUNCT
dti-2185	193	32	91	91	NUM
dti-2185	193	33	)	)	PUNCT
dti-2185	193	34	.	.	PUNCT
dti-2185	194	1	fluorescence	fluorescence	PROPN
dti-2185	194	2	resonance	resonance	NOUN
dti-2185	194	3	energy	energy	NOUN
dti-2185	194	4	transfer	transfer	NOUN
dti-2185	194	5	and	and	CCONJ
dti-2185	194	6	fluorescence	fluorescence	NOUN
dti-2185	194	7	microscopic	microscopic	ADJ
dti-2185	194	8	assays	assay	NOUN
dti-2185	194	9	indicated	indicate	VERB
dti-2185	194	10	that	that	SCONJ
dti-2185	194	11	egcg	egcg	NOUN
dti-2185	194	12	doseand	doseand	VERB
dti-2185	194	13	time	time	NOUN
dti-2185	194	14	-	-	PUNCT
dti-2185	194	15	dependently	dependently	ADV
dti-2185	194	16	induces	induce	VERB
dti-2185	194	17	lipid	lipid	ADJ
dti-2185	194	18	raft	raft	NOUN
dti-2185	194	19	clustering	clustering	NOUN
dti-2185	194	20	and	and	CCONJ
dti-2185	194	21	apoptotic	apoptotic	ADJ
dti-2185	194	22	cell	cell	NOUN
dti-2185	194	23	death	death	NOUN
dti-2185	194	24	.	.	PUNCT
dti-2185	195	1	procyanidins	procyanidin	NOUN
dti-2185	195	2	contained	contain	VERB
dti-2185	195	3	in	in	ADP
dti-2185	195	4	fruits	fruit	NOUN
dti-2185	195	5	and	and	CCONJ
dti-2185	195	6	vegetables	vegetable	NOUN
dti-2185	195	7	are	be	AUX
dti-2185	195	8	oligomeric	oligomeric	ADJ
dti-2185	195	9	flavonoids	flavonoid	NOUN
dti-2185	195	10	with	with	ADP
dti-2185	195	11	the	the	DET
dti-2185	195	12	anticancer	anticancer	NOUN
dti-2185	195	13	activity	activity	NOUN
dti-2185	195	14	.	.	PUNCT
dti-2185	196	1	verstraeten	verstraeten	VERB
dti-2185	196	2	et	et	PROPN
dti-2185	196	3	al	al	PROPN
dti-2185	196	4	treated	treat	VERB
dti-2185	196	5	human	human	PROPN
dti-2185	196	6	acute	acute	PROPN
dti-2185	196	7	t	t	PROPN
dti-2185	196	8	-	-	PUNCT
dti-2185	196	9	cell	cell	NOUN
dti-2185	196	10	leukemia	leukemia	NOUN
dti-2185	196	11	(	(	PUNCT
dti-2185	196	12	jurkat	jurkat	PROPN
dti-2185	196	13	t	t	PROPN
dti-2185	196	14	)	)	PUNCT
dti-2185	196	15	cells	cell	NOUN
dti-2185	196	16	(	(	PUNCT
dti-2185	196	17	6	6	NUM
dti-2185	196	18	×	×	NOUN
dti-2185	196	19	104	104	NUM
dti-2185	196	20	cells	cell	NOUN
dti-2185	196	21	)	)	PUNCT
dti-2185	196	22	with	with	ADP
dti-2185	196	23	cocoa	cocoa	NOUN
dti-2185	196	24	procyanidins	procyanidin	NOUN
dti-2185	196	25	and	and	CCONJ
dti-2185	196	26	measured	measure	VERB
dti-2185	196	27	fp	fp	PROPN
dti-2185	196	28	(	(	PUNCT
dti-2185	196	29	92	92	NUM
dti-2185	196	30	)	)	PUNCT
dti-2185	196	31	.	.	PUNCT
dti-2185	197	1	dimeric	dimeric	ADJ
dti-2185	197	2	procyanidin	procyanidin	NOUN
dti-2185	197	3	increased	increase	VERB
dti-2185	197	4	the	the	DET
dti-2185	197	5	fluidity	fluidity	NOUN
dti-2185	197	6	of	of	ADP
dti-2185	197	7	plasma	plasma	NOUN
dti-2185	197	8	membranes	membrane	NOUN
dti-2185	197	9	in	in	ADP
dti-2185	197	10	a	a	DET
dti-2185	197	11	concentration	concentration	NOUN
dti-2185	197	12	-	-	PUNCT
dti-2185	197	13	dependent	dependent	ADJ
dti-2185	197	14	manner	manner	NOUN
dti-2185	197	15	at	at	ADP
dti-2185	197	16	0.05	0.05	NUM
dti-2185	197	17	-	-	SYM
dti-2185	197	18	1	1	NUM
dti-2185	197	19	μg/	μg/	NOUN
dti-2185	197	20	ml	ml	NOUN
dti-2185	197	21	.	.	PUNCT
dti-2185	198	1	in	in	ADP
dti-2185	198	2	the	the	DET
dti-2185	198	3	following	follow	VERB
dti-2185	198	4	experiment	experiment	NOUN
dti-2185	198	5	,	,	PUNCT
dti-2185	198	6	they	they	PRON
dti-2185	198	7	incubated	incubate	VERB
dti-2185	198	8	human	human	ADJ
dti-2185	198	9	colon	colon	NOUN
dti-2185	198	10	cancer	cancer	NOUN
dti-2185	198	11	(	(	PUNCT
dti-2185	198	12	caco-2	caco-2	NOUN
dti-2185	198	13	)	)	PUNCT
dti-2185	198	14	cells	cell	NOUN
dti-2185	198	15	with	with	ADP
dti-2185	198	16	10	10	NUM
dti-2185	198	17	μm	μm	NOUN
dti-2185	198	18	hexameric	hexameric	NOUN
dti-2185	198	19	procyanidin	procyanidin	NOUN
dti-2185	198	20	in	in	ADP
dti-2185	198	21	the	the	DET
dti-2185	198	22	absence	absence	NOUN
dti-2185	198	23	or	or	CCONJ
dti-2185	198	24	presence	presence	NOUN
dti-2185	198	25	of	of	ADP
dti-2185	198	26	2.5	2.5	NUM
dti-2185	198	27	mm	mm	PROPN
dti-2185	198	28	mbc	mbc	PROPN
dti-2185	198	29	(	(	PUNCT
dti-2185	198	30	93	93	NUM
dti-2185	198	31	)	)	PUNCT
dti-2185	198	32	.	.	PUNCT
dti-2185	199	1	in	in	ADP
dti-2185	199	2	contrast	contrast	NOUN
dti-2185	199	3	to	to	ADP
dti-2185	199	4	dimeric	dimeric	ADJ
dti-2185	199	5	procyanidin	procyanidin	NOUN
dti-2185	199	6	,	,	PUNCT
dti-2185	199	7	hexameric	hexameric	NOUN
dti-2185	199	8	procyanidin	procyanidin	NOUN
dti-2185	199	9	decreased	decrease	VERB
dti-2185	199	10	the	the	DET
dti-2185	199	11	fluidity	fluidity	NOUN
dti-2185	199	12	of	of	ADP
dti-2185	199	13	plasma	plasma	NOUN
dti-2185	199	14	membranes	membrane	NOUN
dti-2185	199	15	,	,	PUNCT
dti-2185	199	16	although	although	SCONJ
dti-2185	199	17	its	its	PRON
dti-2185	199	18	membrane	membrane	NOUN
dti-2185	199	19	interactivity	interactivity	NOUN
dti-2185	199	20	was	be	AUX
dti-2185	199	21	lost	lose	VERB
dti-2185	199	22	by	by	ADP
dti-2185	199	23	cholesterol	cholesterol	NOUN
dti-2185	199	24	-	-	PUNCT
dti-2185	199	25	depleting	deplete	VERB
dti-2185	199	26	mbc	mbc	PROPN
dti-2185	199	27	.	.	PUNCT
dti-2185	200	1	this	this	DET
dti-2185	200	2	procyanidin	procyanidin	NOUN
dti-2185	200	3	also	also	ADV
dti-2185	200	4	prevented	prevent	VERB
dti-2185	200	5	lipid	lipid	ADJ
dti-2185	200	6	raft	raft	NOUN
dti-2185	200	7	disruption	disruption	NOUN
dti-2185	200	8	induced	induce	VERB
dti-2185	200	9	by	by	ADP
dti-2185	200	10	mbc	mbc	PROPN
dti-2185	200	11	or	or	CCONJ
dti-2185	200	12	deoxycholate	deoxycholate	ADJ
dti-2185	200	13	(	(	PUNCT
dti-2185	200	14	cholesterol	cholesterol	NOUN
dti-2185	200	15	depletion	depletion	NOUN
dti-2185	200	16	/	/	SYM
dti-2185	200	17	redistribution	redistribution	NOUN
dti-2185	200	18	)	)	PUNCT
dti-2185	200	19	.	.	PUNCT
dti-2185	201	1	stilbenoids	stilbenoid	NOUN
dti-2185	201	2	resveratrol	resveratrol	VERB
dti-2185	201	3	present	present	NOUN
dti-2185	201	4	in	in	ADP
dti-2185	201	5	grape	grape	NOUN
dti-2185	201	6	skins	skin	NOUN
dti-2185	201	7	and	and	CCONJ
dti-2185	201	8	seeds	seed	NOUN
dti-2185	201	9	has	have	VERB
dti-2185	201	10	anticancer	anticancer	NOUN
dti-2185	201	11	,	,	PUNCT
dti-2185	201	12	antioxidant	antioxidant	ADJ
dti-2185	201	13	and	and	CCONJ
dti-2185	201	14	cardioprotective	cardioprotective	ADJ
dti-2185	201	15	property	property	NOUN
dti-2185	201	16	.	.	PUNCT
dti-2185	202	1	neves	neves	PROPN
dti-2185	202	2	et	et	PROPN
dti-2185	202	3	al	al	PROPN
dti-2185	202	4	treated	treat	VERB
dti-2185	202	5	luvs	luvs	PROPN
dti-2185	202	6	prepared	prepare	VERB
dti-2185	202	7	with	with	ADP
dti-2185	202	8	egg	egg	NOUN
dti-2185	202	9	phosphatidylcholine	phosphatidylcholine	NOUN
dti-2185	202	10	,	,	PUNCT
dti-2185	202	11	sm	sm	PROPN
dti-2185	202	12	and	and	CCONJ
dti-2185	202	13	cholesterol	cholesterol	NOUN
dti-2185	202	14	(	(	PUNCT
dti-2185	202	15	1:1:1	1:1:1	PROPN
dti-2185	202	16	molar	molar	ADJ
dti-2185	202	17	ratio	ratio	NOUN
dti-2185	202	18	)	)	PUNCT
dti-2185	202	19	with	with	ADP
dti-2185	202	20	10	10	NUM
dti-2185	202	21	-	-	SYM
dti-2185	202	22	80	80	NUM
dti-2185	202	23	μm	μm	NOUN
dti-2185	202	24	resveratrol	resveratrol	NOUN
dti-2185	202	25	to	to	PART
dti-2185	202	26	investigate	investigate	VERB
dti-2185	202	27	the	the	DET
dti-2185	202	28	effects	effect	NOUN
dti-2185	202	29	on	on	ADP
dti-2185	202	30	raft	raft	NOUN
dti-2185	202	31	model	model	NOUN
dti-2185	202	32	membranes	membrane	NOUN
dti-2185	202	33	by	by	ADP
dti-2185	202	34	three	three	NUM
dti-2185	202	35	different	different	ADJ
dti-2185	202	36	methods	method	NOUN
dti-2185	202	37	(	(	PUNCT
dti-2185	202	38	94	94	NUM
dti-2185	202	39	)	)	PUNCT
dti-2185	202	40	.	.	PUNCT
dti-2185	203	1	resveratrol	resveratrol	NOUN
dti-2185	203	2	induced	induce	VERB
dti-2185	203	3	the	the	DET
dti-2185	203	4	phase	phase	NOUN
dti-2185	203	5	separation	separation	NOUN
dti-2185	203	6	and	and	CCONJ
dti-2185	203	7	formed	form	VERB
dti-2185	203	8	the	the	DET
dti-2185	203	9	ordered	order	VERB
dti-2185	203	10	membrane	membrane	NOUN
dti-2185	203	11	domains	domain	NOUN
dti-2185	203	12	at	at	ADP
dti-2185	203	13	concentrations	concentration	NOUN
dti-2185	203	14	higher	high	ADJ
dti-2185	203	15	than	than	ADP
dti-2185	203	16	10	10	NUM
dti-2185	203	17	μm	μm	NOUN
dti-2185	203	18	.	.	PUNCT
dti-2185	204	1	such	such	ADJ
dti-2185	204	2	effects	effect	NOUN
dti-2185	204	3	were	be	AUX
dti-2185	204	4	more	more	ADV
dti-2185	204	5	pronounced	pronounce	VERB
dti-2185	204	6	in	in	ADP
dti-2185	204	7	the	the	DET
dti-2185	204	8	presence	presence	NOUN
dti-2185	204	9	of	of	ADP
dti-2185	204	10	cholesterol	cholesterol	NOUN
dti-2185	204	11	and	and	CCONJ
dti-2185	204	12	sm	sm	PROPN
dti-2185	204	13	.	.	PUNCT
dti-2185	205	1	resveratrol	resveratrol	NOUN
dti-2185	205	2	was	be	AUX
dti-2185	205	3	also	also	ADV
dti-2185	205	4	effective	effective	ADJ
dti-2185	205	5	at	at	ADP
dti-2185	205	6	80	80	NUM
dti-2185	205	7	μm	μm	NOUN
dti-2185	205	8	in	in	ADP
dti-2185	205	9	enhancing	enhance	VERB
dti-2185	205	10	the	the	DET
dti-2185	205	11	membrane	membrane	NOUN
dti-2185	205	12	resistance	resistance	NOUN
dti-2185	205	13	to	to	ADP
dti-2185	205	14	triton	triton	PROPN
dti-2185	205	15	x-100	x-100	PROPN
dti-2185	205	16	.	.	PUNCT
dti-2185	206	1	anthraquinonoids	anthraquinonoids	PROPN
dti-2185	206	2	pharmacological	pharmacological	ADJ
dti-2185	206	3	effects	effect	NOUN
dti-2185	206	4	of	of	ADP
dti-2185	206	5	aloe	aloe	PROPN
dti-2185	206	6	are	be	AUX
dti-2185	206	7	attributed	attribute	VERB
dti-2185	206	8	to	to	PART
dti-2185	206	9	anthraquinonoid	anthraquinonoid	VERB
dti-2185	206	10	component	component	NOUN
dti-2185	206	11	emodin	emodin	PROPN
dti-2185	206	12	and	and	CCONJ
dti-2185	206	13	aloin	aloin	VERB
dti-2185	206	14	(	(	PUNCT
dti-2185	206	15	barbaloin	barbaloin	PROPN
dti-2185	206	16	)	)	PUNCT
dti-2185	206	17	.	.	PUNCT
dti-2185	207	1	dsc	dsc	NOUN
dti-2185	207	2	experiments	experiment	NOUN
dti-2185	207	3	of	of	ADP
dti-2185	207	4	alves	alves	PROPN
dti-2185	207	5	et	et	PROPN
dti-2185	207	6	al	al	PROPN
dti-2185	207	7	demonstrated	demonstrate	VERB
dti-2185	207	8	that	that	SCONJ
dti-2185	207	9	emodin	emodin	NOUN
dti-2185	207	10	interacts	interact	VERB
dti-2185	207	11	with	with	ADP
dti-2185	207	12	mlvs	mlv	NOUN
dti-2185	207	13	composed	compose	VERB
dti-2185	207	14	of	of	ADP
dti-2185	207	15	dmpc	dmpc	NOUN
dti-2185	207	16	to	to	PART
dti-2185	207	17	reduce	reduce	VERB
dti-2185	207	18	the	the	DET
dti-2185	207	19	phase	phase	NOUN
dti-2185	207	20	transition	transition	NOUN
dti-2185	207	21	temperature	temperature	NOUN
dti-2185	207	22	at	at	ADP
dti-2185	207	23	1	1	NUM
dti-2185	207	24	-	-	SYM
dti-2185	207	25	5	5	NUM
dti-2185	207	26	mol%	mol%	NOUN
dti-2185	207	27	more	more	ADV
dti-2185	207	28	potently	potently	ADV
dti-2185	207	29	than	than	ADP
dti-2185	207	30	aloin	aloin	VERB
dti-2185	207	31	(	(	PUNCT
dti-2185	207	32	95	95	NUM
dti-2185	207	33	)	)	PUNCT
dti-2185	207	34	.	.	PUNCT
dti-2185	208	1	meng	meng	PROPN
dti-2185	208	2	et	et	PROPN
dti-2185	208	3	al	al	PROPN
dti-2185	208	4	investigated	investigate	VERB
dti-2185	208	5	the	the	DET
dti-2185	208	6	mechanism	mechanism	NOUN
dti-2185	208	7	underlying	underlie	VERB
dti-2185	208	8	a	a	DET
dti-2185	208	9	vascular	vascular	ADJ
dti-2185	208	10	anti	anti	ADJ
dti-2185	208	11	-	-	ADJ
dti-2185	208	12	inflammatory	inflammatory	ADJ
dti-2185	208	13	effect	effect	NOUN
dti-2185	208	14	of	of	ADP
dti-2185	208	15	aloe	aloe	PROPN
dti-2185	208	16	by	by	ADP
dti-2185	208	17	treating	treat	VERB
dti-2185	208	18	human	human	ADJ
dti-2185	208	19	umbilical	umbilical	ADJ
dti-2185	208	20	vein	vein	ADJ
dti-2185	208	21	endothelial	endothelial	NOUN
dti-2185	208	22	cells	cell	NOUN
dti-2185	208	23	grown	grow	VERB
dti-2185	208	24	to	to	ADP
dti-2185	208	25	approximately	approximately	ADV
dti-2185	208	26	90	90	NUM
dti-2185	208	27	%	%	NOUN
dti-2185	208	28	confluence	confluence	NOUN
dti-2185	208	29	with	with	ADP
dti-2185	208	30	emodin	emodin	PROPN
dti-2185	208	31	(	(	PUNCT
dti-2185	208	32	96	96	NUM
dti-2185	208	33	)	)	PUNCT
dti-2185	208	34	.	.	PUNCT
dti-2185	209	1	emodin	emodin	VERB
dti-2185	209	2	(	(	PUNCT
dti-2185	209	3	10	10	NUM
dti-2185	209	4	-	-	SYM
dti-2185	209	5	50	50	NUM
dti-2185	209	6	μg	μg	NOUN
dti-2185	209	7	/	/	SYM
dti-2185	209	8	ml	ml	NOUN
dti-2185	209	9	)	)	PUNCT
dti-2185	209	10	inhibited	inhibit	VERB
dti-2185	209	11	the	the	DET
dti-2185	209	12	expression	expression	NOUN
dti-2185	209	13	of	of	ADP
dti-2185	209	14	proinflammatory	proinflammatory	ADJ
dti-2185	209	15	cytokines	cytokine	NOUN
dti-2185	209	16	and	and	CCONJ
dti-2185	209	17	chemokines	chemokine	NOUN
dti-2185	209	18	induced	induce	VERB
dti-2185	209	19	by	by	ADP
dti-2185	209	20	0.1	0.1	NUM
dti-2185	209	21	μg	μg	PROPN
dti-2185	209	22	/	/	SYM
dti-2185	209	23	ml	ml	NOUN
dti-2185	209	24	lipopolysaccharide	lipopolysaccharide	ADJ
dti-2185	209	25	(	(	PUNCT
dti-2185	209	26	lps	lps	PROPN
dti-2185	209	27	)	)	PUNCT
dti-2185	209	28	.	.	PUNCT
dti-2185	210	1	similar	similar	ADJ
dti-2185	210	2	to	to	ADP
dti-2185	210	3	cholesterol	cholesterol	NOUN
dti-2185	210	4	-	-	PUNCT
dti-2185	210	5	depleting	deplete	VERB
dti-2185	210	6	mbc	mbc	NOUN
dti-2185	210	7	(	(	PUNCT
dti-2185	210	8	5	5	NUM
dti-2185	210	9	-	-	SYM
dti-2185	210	10	12.5	12.5	NUM
dti-2185	210	11	mm	mm	NOUN
dti-2185	210	12	)	)	PUNCT
dti-2185	210	13	,	,	PUNCT
dti-2185	210	14	emodin	emodin	VERB
dti-2185	210	15	(	(	PUNCT
dti-2185	210	16	10	10	NUM
dti-2185	210	17	-	-	SYM
dti-2185	210	18	50	50	NUM
dti-2185	210	19	μg	μg	NOUN
dti-2185	210	20	/	/	SYM
dti-2185	210	21	ml	ml	NOUN
dti-2185	210	22	)	)	PUNCT
dti-2185	210	23	disrupted	disrupt	VERB
dti-2185	210	24	lipid	lipid	NOUN
dti-2185	210	25	rafts	raft	NOUN
dti-2185	210	26	that	that	PRON
dti-2185	210	27	are	be	AUX
dti-2185	210	28	relevant	relevant	ADJ
dti-2185	210	29	to	to	ADP
dti-2185	210	30	the	the	DET
dti-2185	210	31	cell	cell	NOUN
dti-2185	210	32	activation	activation	NOUN
dti-2185	210	33	by	by	ADP
dti-2185	210	34	lps	lps	PROPN
dti-2185	210	35	.	.	PUNCT
dti-2185	211	1	lipid	lipid	NOUN
dti-2185	211	2	raft	raft	NOUN
dti-2185	211	3	disruption	disruption	NOUN
dti-2185	211	4	associated	associate	VERB
dti-2185	211	5	with	with	ADP
dti-2185	211	6	integrin	integrin	NOUN
dti-2185	211	7	signaling	signal	VERB
dti-2185	211	8	pathway	pathway	NOUN
dti-2185	211	9	is	be	AUX
dti-2185	211	10	also	also	ADV
dti-2185	211	11	responsible	responsible	ADJ
dti-2185	211	12	for	for	ADP
dti-2185	211	13	the	the	DET
dti-2185	211	14	inhibitory	inhibitory	ADJ
dti-2185	211	15	effects	effect	NOUN
dti-2185	211	16	of	of	ADP
dti-2185	211	17	emodin	emodin	VERB
dti-2185	211	18	on	on	ADP
dti-2185	211	19	tumor	tumor	NOUN
dti-2185	211	20	cell	cell	NOUN
dti-2185	211	21	adhesion	adhesion	NOUN
dti-2185	211	22	and	and	CCONJ
dti-2185	211	23	spreading	spread	VERB
dti-2185	211	24	(	(	PUNCT
dti-2185	211	25	97	97	NUM
dti-2185	211	26	)	)	PUNCT
dti-2185	211	27	.	.	PUNCT
dti-2185	212	1	terpenoids	terpenoid	NOUN
dti-2185	212	2	triterpenoid	triterpenoid	VERB
dti-2185	212	3	glycosides	glycoside	NOUN
dti-2185	212	4	from	from	ADP
dti-2185	212	5	panax	panax	PROPN
dti-2185	212	6	ginseng	ginseng	NOUN
dti-2185	212	7	and	and	CCONJ
dti-2185	212	8	triterpenoid	triterpenoid	VERB
dti-2185	212	9	saponin	saponin	ADJ
dti-2185	212	10	derivatives	derivative	NOUN
dti-2185	212	11	from	from	ADP
dti-2185	212	12	radix	radix	PROPN
dti-2185	212	13	bupleuri	bupleuri	PROPN
dti-2185	212	14	have	have	VERB
dti-2185	212	15	anti	anti	ADJ
dti-2185	212	16	inflammatory	inflammatory	ADJ
dti-2185	212	17	and	and	CCONJ
dti-2185	212	18	anticancer	anticancer	NOUN
dti-2185	212	19	activity	activity	NOUN
dti-2185	212	20	.	.	PUNCT
dti-2185	213	1	yi	yi	PROPN
dti-2185	213	2	et	et	PROPN
dti-2185	213	3	al	al	PROPN
dti-2185	213	4	treated	treat	VERB
dti-2185	213	5	hela	hela	ADJ
dti-2185	213	6	cells	cell	NOUN
dti-2185	213	7	with	with	ADP
dti-2185	213	8	different	different	ADJ
dti-2185	213	9	ginsenosides	ginsenoside	NOUN
dti-2185	213	10	at	at	ADP
dti-2185	213	11	50	50	NUM
dti-2185	213	12	μm	μm	NOUN
dti-2185	213	13	and	and	CCONJ
dti-2185	213	14	stained	stain	VERB
dti-2185	213	15	the	the	DET
dti-2185	213	16	cells	cell	NOUN
dti-2185	213	17	with	with	ADP
dti-2185	213	18	carboxy	carboxy	PROPN
dti-2185	213	19	laurdan	laurdan	PROPN
dti-2185	213	20	,	,	PUNCT
dti-2185	213	21	followed	follow	VERB
dti-2185	213	22	by	by	ADP
dti-2185	213	23	fluorescence	fluorescence	NOUN
dti-2185	213	24	microscopy	microscopy	NOUN
dti-2185	213	25	and	and	CCONJ
dti-2185	213	26	generalized	generalized	ADJ
dti-2185	213	27	polarization	polarization	NOUN
dti-2185	213	28	imaging	imaging	NOUN
dti-2185	213	29	(	(	PUNCT
dti-2185	213	30	98	98	NUM
dti-2185	213	31	)	)	PUNCT
dti-2185	213	32	.	.	PUNCT
dti-2185	214	1	ginsenosides	ginsenoside	NOUN
dti-2185	214	2	rb2	rb2	PROPN
dti-2185	214	3	,	,	PUNCT
dti-2185	214	4	rc	rc	PROPN
dti-2185	214	5	,	,	PUNCT
dti-2185	214	6	rd	rd	PROPN
dti-2185	214	7	,	,	PUNCT
dti-2185	214	8	re	re	ADP
dti-2185	214	9	,	,	PUNCT
dti-2185	214	10	rf	rf	PROPN
dti-2185	214	11	,	,	PUNCT
dti-2185	214	12	rg1	rg1	PROPN
dti-2185	214	13	,	,	PUNCT
dti-2185	214	14	rg2	rg2	NOUN
dti-2185	214	15	and	and	CCONJ
dti-2185	214	16	rh2	rh2	PROPN
dti-2185	214	17	increased	increase	VERB
dti-2185	214	18	the	the	DET
dti-2185	214	19	fluidity	fluidity	NOUN
dti-2185	214	20	of	of	ADP
dti-2185	214	21	plasma	plasma	NOUN
dti-2185	214	22	membranes	membrane	NOUN
dti-2185	214	23	as	as	ADV
dti-2185	214	24	well	well	ADV
dti-2185	214	25	as	as	ADP
dti-2185	214	26	cholesterol	cholesterol	NOUN
dti-2185	214	27	-	-	PUNCT
dti-2185	214	28	depleting	deplete	VERB
dti-2185	214	29	mbc	mbc	NOUN
dti-2185	214	30	(	(	PUNCT
dti-2185	214	31	10	10	NUM
dti-2185	214	32	mm	mm	NOUN
dti-2185	214	33	)	)	PUNCT
dti-2185	214	34	.	.	PUNCT
dti-2185	215	1	when	when	SCONJ
dti-2185	215	2	fractionating	fractionate	VERB
dti-2185	215	3	the	the	DET
dti-2185	215	4	hela	hela	PROPN
dti-2185	215	5	cells	cell	NOUN
dti-2185	215	6	by	by	ADP
dti-2185	215	7	sdgc	sdgc	NOUN
dti-2185	215	8	,	,	PUNCT
dti-2185	215	9	ginsenoside	ginsenoside	ADV
dti-2185	215	10	rh2	rh2	PROPN
dti-2185	215	11	and	and	CCONJ
dti-2185	215	12	mbc	mbc	PROPN
dti-2185	215	13	reduced	reduce	VERB
dti-2185	215	14	the	the	DET
dti-2185	215	15	concentration	concentration	NOUN
dti-2185	215	16	of	of	ADP
dti-2185	215	17	raft	raft	NOUN
dti-2185	215	18	-	-	PUNCT
dti-2185	215	19	marker	marker	NOUN
dti-2185	215	20	proteins	protein	NOUN
dti-2185	215	21	in	in	ADP
dti-2185	215	22	the	the	DET
dti-2185	215	23	raft	raft	NOUN
dti-2185	215	24	fraction	fraction	NOUN
dti-2185	215	25	,	,	PUNCT
dti-2185	215	26	indicating	indicate	VERB
dti-2185	215	27	that	that	SCONJ
dti-2185	215	28	they	they	PRON
dti-2185	215	29	disrupt	disrupt	VERB
dti-2185	215	30	lipid	lipid	NOUN
dti-2185	215	31	rafts	raft	NOUN
dti-2185	215	32	.	.	PUNCT
dti-2185	216	1	these	these	DET
dti-2185	216	2	effects	effect	NOUN
dti-2185	216	3	of	of	ADP
dti-2185	216	4	ginsenoside	ginsenoside	ADJ
dti-2185	216	5	rh2	rh2	PROPN
dti-2185	216	6	were	be	AUX
dti-2185	216	7	reversed	reverse	VERB
dti-2185	216	8	by	by	ADP
dti-2185	216	9	cholesterol	cholesterol	NOUN
dti-2185	216	10	overloading	overloading	NOUN
dti-2185	216	11	(	(	PUNCT
dti-2185	216	12	20	20	NUM
dti-2185	216	13	μg	μg	NOUN
dti-2185	216	14	/	/	SYM
dti-2185	216	15	ml	ml	NOUN
dti-2185	216	16	)	)	PUNCT
dti-2185	216	17	.	.	PUNCT
dti-2185	217	1	in	in	ADP
dti-2185	217	2	a	a	DET
dti-2185	217	3	cell	cell	NOUN
dti-2185	217	4	culture	culture	NOUN
dti-2185	217	5	study	study	NOUN
dti-2185	217	6	of	of	ADP
dti-2185	217	7	wei	wei	PROPN
dti-2185	217	8	et	et	PROPN
dti-2185	217	9	al	al	PROPN
dti-2185	217	10	(	(	PUNCT
dti-2185	217	11	99	99	NUM
dti-2185	217	12	)	)	PUNCT
dti-2185	217	13	,	,	PUNCT
dti-2185	217	14	3	3	NUM
dti-2185	217	15	-	-	SYM
dti-2185	217	16	12	12	NUM
dti-2185	217	17	μm	μm	NOUN
dti-2185	217	18	saikosaponin	saikosaponin	NOUN
dti-2185	217	19	a	a	DET
dti-2185	217	20	inhibited	inhibited	ADJ
dti-2185	217	21	the	the	DET
dti-2185	217	22	expression	expression	NOUN
dti-2185	217	23	of	of	ADP
dti-2185	217	24	cytokines	cytokine	NOUN
dti-2185	217	25	in	in	ADP
dti-2185	217	26	primary	primary	ADJ
dti-2185	217	27	mouse	mouse	NOUN
dti-2185	217	28	macrophages	macrophage	NOUN
dti-2185	217	29	stimulated	stimulate	VERB
dti-2185	217	30	by	by	ADP
dti-2185	217	31	0.1	0.1	NUM
dti-2185	217	32	μg	μg	NOUN
dti-2185	217	33	/	/	SYM
dti-2185	217	34	ml	ml	NOUN
dti-2185	217	35	lps	lps	PROPN
dti-2185	217	36	.	.	PUNCT
dti-2185	218	1	such	such	ADJ
dti-2185	218	2	inhibitory	inhibitory	ADJ
dti-2185	218	3	effects	effect	NOUN
dti-2185	218	4	were	be	AUX
dti-2185	218	5	attenuated	attenuate	VERB
dti-2185	218	6	by	by	ADP
dti-2185	218	7	replenishment	replenishment	NOUN
dti-2185	218	8	of	of	ADP
dti-2185	218	9	84	84	NUM
dti-2185	218	10	μg	μg	NOUN
dti-2185	218	11	/	/	SYM
dti-2185	218	12	ml	ml	NOUN
dti-2185	218	13	cholesterol	cholesterol	NOUN
dti-2185	218	14	,	,	PUNCT
dti-2185	218	15	while	while	SCONJ
dti-2185	218	16	3	3	NUM
dti-2185	218	17	-	-	SYM
dti-2185	218	18	12	12	NUM
dti-2185	218	19	μm	μm	NOUN
dti-2185	218	20	saikosaponin	saikosaponin	NOUN
dti-2185	218	21	a	a	DET
dti-2185	218	22	reduced	reduced	ADJ
dti-2185	218	23	cholesterol	cholesterol	NOUN
dti-2185	218	24	levels	level	NOUN
dti-2185	218	25	in	in	ADP
dti-2185	218	26	macrophage	macrophage	ADJ
dti-2185	218	27	membranes	membrane	NOUN
dti-2185	218	28	.	.	PUNCT
dti-2185	219	1	saikosaponin	saikosaponin	ADJ
dti-2185	219	2	a	a	DET
dti-2185	219	3	(	(	PUNCT
dti-2185	219	4	3	3	NUM
dti-2185	219	5	-	-	SYM
dti-2185	219	6	12	12	NUM
dti-2185	219	7	μm	μm	NOUN
dti-2185	219	8	)	)	PUNCT
dti-2185	219	9	and	and	CCONJ
dti-2185	219	10	mbc	mbc	PROPN
dti-2185	219	11	(	(	PUNCT
dti-2185	219	12	10	10	NUM
dti-2185	219	13	mm	mm	NOUN
dti-2185	219	14	)	)	PUNCT
dti-2185	219	15	also	also	ADV
dti-2185	219	16	inhibited	inhibit	VERB
dti-2185	219	17	the	the	DET
dti-2185	219	18	lps	lps	PROPN
dti-2185	219	19	-	-	PUNCT
dti-2185	219	20	induced	induce	VERB
dti-2185	219	21	interaction	interaction	NOUN
dti-2185	219	22	of	of	ADP
dti-2185	219	23	drugs	drug	NOUN
dti-2185	219	24	with	with	ADP
dti-2185	219	25	lipid	lipid	ADJ
dti-2185	219	26	rafts44	rafts44	NOUN
dti-2185	220	1	©	©	PROPN
dti-2185	220	2	2020	2020	NUM
dti-2185	221	1	the	the	DET
dti-2185	221	2	authors	author	NOUN
dti-2185	221	3	.	.	PUNCT
dti-2185	221	4	published	publish	VERB
dti-2185	221	5	by	by	ADP
dti-2185	221	6	aboutscience	aboutscience	NOUN
dti-2185	221	7	localization	localization	NOUN
dti-2185	221	8	in	in	ADP
dti-2185	221	9	lipid	lipid	ADJ
dti-2185	221	10	rafts	raft	NOUN
dti-2185	221	11	of	of	ADP
dti-2185	221	12	toll	toll	NOUN
dti-2185	221	13	-	-	PUNCT
dti-2185	221	14	like	like	ADJ
dti-2185	221	15	receptors	receptor	NOUN
dti-2185	221	16	that	that	PRON
dti-2185	221	17	play	play	VERB
dti-2185	221	18	a	a	DET
dti-2185	221	19	crucial	crucial	ADJ
dti-2185	221	20	role	role	NOUN
dti-2185	221	21	in	in	ADP
dti-2185	221	22	the	the	DET
dti-2185	221	23	innate	innate	ADJ
dti-2185	221	24	immune	immune	ADJ
dti-2185	221	25	system	system	NOUN
dti-2185	221	26	.	.	PUNCT
dti-2185	222	1	conclusions	conclusion	NOUN
dti-2185	222	2	results	result	NOUN
dti-2185	222	3	of	of	ADP
dti-2185	222	4	the	the	DET
dti-2185	222	5	literature	literature	NOUN
dti-2185	222	6	search	search	NOUN
dti-2185	222	7	indicate	indicate	VERB
dti-2185	222	8	that	that	SCONJ
dti-2185	222	9	different	different	ADJ
dti-2185	222	10	classes	class	NOUN
dti-2185	222	11	of	of	ADP
dti-2185	222	12	drugs	drug	NOUN
dti-2185	222	13	interact	interact	VERB
dti-2185	222	14	with	with	ADP
dti-2185	222	15	raft	raft	NOUN
dti-2185	222	16	model	model	NOUN
dti-2185	222	17	membranes	membrane	NOUN
dti-2185	222	18	and	and	CCONJ
dti-2185	222	19	cellular	cellular	ADJ
dti-2185	222	20	membrane	membrane	NOUN
dti-2185	222	21	lipid	lipid	NOUN
dti-2185	222	22	rafts	raft	NOUN
dti-2185	222	23	in	in	ADP
dti-2185	222	24	addition	addition	NOUN
dti-2185	222	25	to	to	ADP
dti-2185	222	26	interacting	interact	VERB
dti-2185	222	27	directly	directly	ADV
dti-2185	222	28	with	with	ADP
dti-2185	222	29	membrane	membrane	NOUN
dti-2185	222	30	receptors	receptor	NOUN
dti-2185	222	31	,	,	PUNCT
dti-2185	222	32	ion	ion	NOUN
dti-2185	222	33	channels	channel	NOUN
dti-2185	222	34	and	and	CCONJ
dti-2185	222	35	enzymes	enzyme	NOUN
dti-2185	222	36	.	.	PUNCT
dti-2185	223	1	they	they	PRON
dti-2185	223	2	could	could	AUX
dti-2185	223	3	physicochemically	physicochemically	ADV
dti-2185	223	4	modify	modify	VERB
dti-2185	223	5	membrane	membrane	NOUN
dti-2185	223	6	lipid	lipid	NOUN
dti-2185	223	7	rafts	raft	NOUN
dti-2185	223	8	to	to	PART
dti-2185	223	9	be	be	AUX
dti-2185	223	10	a	a	DET
dti-2185	223	11	platform	platform	NOUN
dti-2185	223	12	for	for	ADP
dti-2185	223	13	functional	functional	ADJ
dti-2185	223	14	proteins	protein	NOUN
dti-2185	223	15	and	and	CCONJ
dti-2185	223	16	the	the	DET
dti-2185	223	17	membranes	membrane	NOUN
dti-2185	223	18	surrounding	surround	VERB
dti-2185	223	19	such	such	ADJ
dti-2185	223	20	raft	raft	NOUN
dti-2185	223	21	domains	domain	NOUN
dti-2185	223	22	,	,	PUNCT
dti-2185	223	23	affecting	affect	VERB
dti-2185	223	24	the	the	DET
dti-2185	223	25	organizational	organizational	ADJ
dti-2185	223	26	integrity	integrity	NOUN
dti-2185	223	27	of	of	ADP
dti-2185	223	28	lipid	lipid	ADJ
dti-2185	223	29	rafts	raft	NOUN
dti-2185	223	30	with	with	ADP
dti-2185	223	31	the	the	DET
dti-2185	223	32	subsequent	subsequent	ADJ
dti-2185	223	33	alteration	alteration	NOUN
dti-2185	223	34	of	of	ADP
dti-2185	223	35	receptor	receptor	NOUN
dti-2185	223	36	,	,	PUNCT
dti-2185	223	37	channel	channel	NOUN
dti-2185	223	38	and	and	CCONJ
dti-2185	223	39	enzyme	enzyme	NOUN
dti-2185	223	40	activity	activity	NOUN
dti-2185	223	41	,	,	PUNCT
dti-2185	223	42	thereby	thereby	ADV
dti-2185	223	43	producing	produce	VERB
dti-2185	223	44	pharmacological	pharmacological	ADJ
dti-2185	223	45	effects	effect	NOUN
dti-2185	223	46	.	.	PUNCT
dti-2185	224	1	with	with	ADP
dti-2185	224	2	respect	respect	NOUN
dti-2185	224	3	to	to	ADP
dti-2185	224	4	the	the	DET
dti-2185	224	5	induced	induced	ADJ
dti-2185	224	6	membrane	membrane	NOUN
dti-2185	224	7	modification	modification	NOUN
dti-2185	224	8	,	,	PUNCT
dti-2185	224	9	raft	raft	NOUN
dti-2185	224	10	-	-	PUNCT
dti-2185	224	11	acting	act	VERB
dti-2185	224	12	drugs	drug	NOUN
dti-2185	224	13	are	be	AUX
dti-2185	224	14	characterized	characterize	VERB
dti-2185	224	15	as	as	ADP
dti-2185	224	16	ones	one	NOUN
dti-2185	224	17	to	to	PART
dti-2185	224	18	decrease	decrease	VERB
dti-2185	224	19	membrane	membrane	ADJ
dti-2185	224	20	fluidity	fluidity	NOUN
dti-2185	224	21	,	,	PUNCT
dti-2185	224	22	induce	induce	VERB
dti-2185	224	23	lo	lo	NOUN
dti-2185	224	24	phase	phase	NOUN
dti-2185	224	25	or	or	CCONJ
dti-2185	224	26	order	order	VERB
dti-2185	224	27	plasma	plasma	NOUN
dti-2185	224	28	membranes	membrane	NOUN
dti-2185	224	29	,	,	PUNCT
dti-2185	224	30	leading	lead	VERB
dti-2185	224	31	to	to	ADP
dti-2185	224	32	lipid	lipid	NOUN
dti-2185	224	33	raft	raft	NOUN
dti-2185	224	34	formation	formation	NOUN
dti-2185	224	35	;	;	PUNCT
dti-2185	224	36	and	and	CCONJ
dti-2185	224	37	ones	one	NOUN
dti-2185	224	38	to	to	PART
dti-2185	224	39	increase	increase	VERB
dti-2185	224	40	membrane	membrane	ADJ
dti-2185	224	41	fluidity	fluidity	NOUN
dti-2185	224	42	,	,	PUNCT
dti-2185	224	43	induce	induce	VERB
dti-2185	224	44	ld	ld	NOUN
dti-2185	224	45	phase	phase	NOUN
dti-2185	224	46	or	or	CCONJ
dti-2185	224	47	reduce	reduce	VERB
dti-2185	224	48	phase	phase	NOUN
dti-2185	224	49	transition	transition	NOUN
dti-2185	224	50	temperature	temperature	NOUN
dti-2185	224	51	,	,	PUNCT
dti-2185	224	52	leading	lead	VERB
dti-2185	224	53	to	to	ADP
dti-2185	224	54	lipid	lipid	NOUN
dti-2185	224	55	raft	raft	NOUN
dti-2185	224	56	disruption	disruption	NOUN
dti-2185	224	57	.	.	PUNCT
dti-2185	225	1	targeting	target	VERB
dti-2185	225	2	lipid	lipid	NOUN
dti-2185	225	3	raft	raft	NOUN
dti-2185	225	4	membrane	membrane	NOUN
dti-2185	225	5	domains	domain	NOUN
dti-2185	225	6	would	would	AUX
dti-2185	225	7	open	open	VERB
dti-2185	225	8	a	a	DET
dti-2185	225	9	new	new	ADJ
dti-2185	225	10	way	way	NOUN
dti-2185	225	11	for	for	ADP
dti-2185	225	12	drug	drug	NOUN
dti-2185	225	13	design	design	NOUN
dti-2185	225	14	and	and	CCONJ
dti-2185	225	15	development	development	NOUN
dti-2185	225	16	.	.	PUNCT
dti-2185	226	1	given	give	VERB
dti-2185	226	2	the	the	DET
dti-2185	226	3	critical	critical	ADJ
dti-2185	226	4	role	role	NOUN
dti-2185	226	5	of	of	ADP
dti-2185	226	6	lipid	lipid	ADJ
dti-2185	226	7	rafts	raft	NOUN
dti-2185	226	8	/	/	SYM
dti-2185	226	9	caveolae	caveolae	NOUN
dti-2185	226	10	in	in	ADP
dti-2185	226	11	cellular	cellular	ADJ
dti-2185	226	12	signal	signal	NOUN
dti-2185	226	13	transduction	transduction	NOUN
dti-2185	226	14	,	,	PUNCT
dti-2185	226	15	odontology	odontology	NOUN
dti-2185	226	16	may	may	AUX
dti-2185	226	17	be	be	AUX
dti-2185	226	18	the	the	DET
dti-2185	226	19	promising	promising	ADJ
dti-2185	226	20	field	field	NOUN
dti-2185	226	21	to	to	PART
dti-2185	226	22	which	which	PRON
dti-2185	226	23	a	a	DET
dti-2185	226	24	raft	raft	NOUN
dti-2185	226	25	-	-	PUNCT
dti-2185	226	26	targeting	target	VERB
dti-2185	226	27	concept	concept	NOUN
dti-2185	226	28	is	be	AUX
dti-2185	226	29	applied	apply	VERB
dti-2185	226	30	.	.	PUNCT
dti-2185	227	1	anticancer	anticancer	NOUN
dti-2185	227	2	drugs	drug	NOUN
dti-2185	227	3	interact	interact	VERB
dti-2185	227	4	with	with	ADP
dti-2185	227	5	membrane	membrane	NOUN
dti-2185	227	6	lipid	lipid	NOUN
dti-2185	227	7	rafts	raft	NOUN
dti-2185	227	8	to	to	PART
dti-2185	227	9	affect	affect	VERB
dti-2185	227	10	their	their	PRON
dti-2185	227	11	physicochemical	physicochemical	ADJ
dti-2185	227	12	property	property	NOUN
dti-2185	227	13	and	and	CCONJ
dti-2185	227	14	organizational	organizational	ADJ
dti-2185	227	15	integrity	integrity	NOUN
dti-2185	227	16	in	in	ADP
dti-2185	227	17	association	association	NOUN
dti-2185	227	18	with	with	ADP
dti-2185	227	19	apoptosis	apoptosis	NOUN
dti-2185	227	20	induction	induction	NOUN
dti-2185	227	21	.	.	PUNCT
dti-2185	228	1	lipid	lipid	NOUN
dti-2185	228	2	raft	raft	NOUN
dti-2185	228	3	membrane	membrane	NOUN
dti-2185	228	4	domains	domain	NOUN
dti-2185	228	5	are	be	AUX
dti-2185	228	6	responsible	responsible	ADJ
dti-2185	228	7	for	for	ADP
dti-2185	228	8	cancer	cancer	NOUN
dti-2185	228	9	cell	cell	NOUN
dti-2185	228	10	adhesion	adhesion	NOUN
dti-2185	228	11	and	and	CCONJ
dti-2185	228	12	migration	migration	NOUN
dti-2185	228	13	,	,	PUNCT
dti-2185	228	14	and	and	CCONJ
dti-2185	228	15	the	the	DET
dti-2185	228	16	levels	level	NOUN
dti-2185	228	17	of	of	ADP
dti-2185	228	18	cholesterol	cholesterol	NOUN
dti-2185	228	19	-	-	PUNCT
dti-2185	228	20	rich	rich	ADJ
dti-2185	228	21	lipid	lipid	NOUN
dti-2185	228	22	rafts	raft	NOUN
dti-2185	228	23	are	be	AUX
dti-2185	228	24	elevated	elevate	VERB
dti-2185	228	25	in	in	ADP
dti-2185	228	26	cancer	cancer	NOUN
dti-2185	228	27	cells	cell	NOUN
dti-2185	228	28	compared	compare	VERB
dti-2185	228	29	with	with	ADP
dti-2185	228	30	normal	normal	ADJ
dti-2185	228	31	counterparts	counterpart	NOUN
dti-2185	228	32	(	(	PUNCT
dti-2185	228	33	100,101	100,101	NUM
dti-2185	228	34	)	)	PUNCT
dti-2185	228	35	.	.	PUNCT
dti-2185	229	1	while	while	SCONJ
dti-2185	229	2	phytochemicals	phytochemical	NOUN
dti-2185	229	3	interact	interact	VERB
dti-2185	229	4	with	with	ADP
dti-2185	229	5	membrane	membrane	NOUN
dti-2185	229	6	lipid	lipid	NOUN
dti-2185	229	7	rafts	raft	NOUN
dti-2185	229	8	and	and	CCONJ
dti-2185	229	9	regulate	regulate	VERB
dti-2185	229	10	raft	raft	NOUN
dti-2185	229	11	formation	formation	NOUN
dti-2185	229	12	(	(	PUNCT
dti-2185	229	13	83,85	83,85	NUM
dti-2185	229	14	)	)	PUNCT
dti-2185	229	15	,	,	PUNCT
dti-2185	229	16	such	such	ADJ
dti-2185	229	17	interactivity	interactivity	NOUN
dti-2185	229	18	is	be	AUX
dti-2185	229	19	responsible	responsible	ADJ
dti-2185	229	20	for	for	ADP
dti-2185	229	21	their	their	PRON
dti-2185	229	22	diverse	diverse	ADJ
dti-2185	229	23	bioactivities	bioactivitie	NOUN
dti-2185	229	24	including	include	VERB
dti-2185	229	25	apoptosis	apoptosis	NOUN
dti-2185	229	26	induction	induction	NOUN
dti-2185	229	27	.	.	PUNCT
dti-2185	230	1	among	among	ADP
dti-2185	230	2	raft	raft	NOUN
dti-2185	230	3	-	-	PUNCT
dti-2185	230	4	targeting	target	VERB
dti-2185	230	5	compounds	compound	NOUN
dti-2185	230	6	,	,	PUNCT
dti-2185	230	7	alkylphospholipids	alkylphospholipid	NOUN
dti-2185	230	8	and	and	CCONJ
dti-2185	230	9	flavonoids	flavonoid	NOUN
dti-2185	230	10	could	could	AUX
dti-2185	230	11	be	be	AUX
dti-2185	230	12	a	a	DET
dti-2185	230	13	novel	novel	ADJ
dti-2185	230	14	type	type	NOUN
dti-2185	230	15	of	of	ADP
dti-2185	230	16	anticancer	anticancer	NOUN
dti-2185	230	17	drug	drug	NOUN
dti-2185	230	18	.	.	PUNCT
dti-2185	231	1	since	since	SCONJ
dti-2185	231	2	an	an	DET
dti-2185	231	3	outbreak	outbreak	NOUN
dti-2185	231	4	of	of	ADP
dti-2185	231	5	atypical	atypical	ADJ
dti-2185	231	6	pneumonia	pneumonia	NOUN
dti-2185	231	7	was	be	AUX
dti-2185	231	8	first	first	ADV
dti-2185	231	9	reported	report	VERB
dti-2185	231	10	in	in	ADP
dti-2185	231	11	wuhan	wuhan	PROPN
dti-2185	231	12	(	(	PUNCT
dti-2185	231	13	china	china	PROPN
dti-2185	231	14	)	)	PUNCT
dti-2185	231	15	in	in	ADP
dti-2185	231	16	december	december	PROPN
dti-2185	231	17	2019	2019	NUM
dti-2185	231	18	,	,	PUNCT
dti-2185	231	19	novel	novel	ADJ
dti-2185	231	20	coronavirus	coronavirus	NOUN
dti-2185	231	21	or	or	CCONJ
dti-2185	231	22	severe	severe	ADJ
dti-2185	231	23	acute	acute	ADJ
dti-2185	231	24	respiratory	respiratory	ADJ
dti-2185	231	25	syndrome	syndrome	NOUN
dti-2185	231	26	coronavirus	coronavirus	NOUN
dti-2185	231	27	2	2	NUM
dti-2185	231	28	(	(	PUNCT
dti-2185	231	29	sars	sar	NOUN
dti-2185	231	30	-	-	PUNCT
dti-2185	231	31	cov-2	cov-2	NOUN
dti-2185	231	32	)	)	PUNCT
dti-2185	231	33	infections	infection	NOUN
dti-2185	231	34	have	have	AUX
dti-2185	231	35	spread	spread	VERB
dti-2185	231	36	worldwide	worldwide	ADV
dti-2185	231	37	,	,	PUNCT
dti-2185	231	38	causing	cause	VERB
dti-2185	231	39	a	a	DET
dti-2185	231	40	global	global	ADJ
dti-2185	231	41	pandemic	pandemic	NOUN
dti-2185	231	42	of	of	ADP
dti-2185	231	43	coronavirus	coronavirus	NOUN
dti-2185	231	44	disease	disease	NOUN
dti-2185	231	45	2019	2019	NUM
dti-2185	231	46	(	(	PUNCT
dti-2185	231	47	covid-19	covid-19	PROPN
dti-2185	231	48	)	)	PUNCT
dti-2185	231	49	.	.	PUNCT
dti-2185	232	1	sars	sars	PROPN
dti-2185	232	2	-	-	PUNCT
dti-2185	232	3	cov-2	cov-2	NOUN
dti-2185	232	4	spike	spike	ADJ
dti-2185	232	5	proteins	protein	NOUN
dti-2185	232	6	have	have	VERB
dti-2185	232	7	a	a	DET
dti-2185	232	8	strong	strong	ADJ
dti-2185	232	9	binding	bind	VERB
dti-2185	232	10	affinity	affinity	NOUN
dti-2185	232	11	to	to	ADP
dti-2185	232	12	human	human	ADJ
dti-2185	232	13	angiotensin	angiotensin	NOUN
dti-2185	232	14	-	-	PUNCT
dti-2185	232	15	converting	convert	VERB
dti-2185	232	16	enzyme	enzyme	NOUN
dti-2185	232	17	2	2	NUM
dti-2185	232	18	(	(	PUNCT
dti-2185	232	19	ace2	ace2	PROPN
dti-2185	232	20	)	)	PUNCT
dti-2185	232	21	(	(	PUNCT
dti-2185	232	22	102	102	NUM
dti-2185	232	23	)	)	PUNCT
dti-2185	232	24	.	.	PUNCT
dti-2185	233	1	host	host	NOUN
dti-2185	233	2	cell	cell	NOUN
dti-2185	233	3	ace2	ace2	NOUN
dti-2185	233	4	receptors	receptor	NOUN
dti-2185	233	5	,	,	PUNCT
dti-2185	233	6	which	which	PRON
dti-2185	233	7	are	be	AUX
dti-2185	233	8	a	a	DET
dti-2185	233	9	cell	cell	NOUN
dti-2185	233	10	-	-	PUNCT
dti-2185	233	11	specific	specific	ADJ
dti-2185	233	12	target	target	NOUN
dti-2185	233	13	of	of	ADP
dti-2185	233	14	and	and	CCONJ
dti-2185	233	15	responsible	responsible	ADJ
dti-2185	233	16	for	for	ADP
dti-2185	233	17	the	the	DET
dti-2185	233	18	cellular	cellular	ADJ
dti-2185	233	19	entry	entry	NOUN
dti-2185	233	20	of	of	ADP
dti-2185	233	21	sars	sar	NOUN
dti-2185	233	22	-	-	PUNCT
dti-2185	233	23	cov-2	cov-2	NOUN
dti-2185	233	24	,	,	PUNCT
dti-2185	233	25	are	be	AUX
dti-2185	233	26	localized	localize	VERB
dti-2185	233	27	in	in	ADP
dti-2185	233	28	lipid	lipid	ADJ
dti-2185	233	29	rafts	raft	NOUN
dti-2185	233	30	(	(	PUNCT
dti-2185	233	31	103	103	NUM
dti-2185	233	32	)	)	PUNCT
dti-2185	233	33	.	.	PUNCT
dti-2185	234	1	cholesterol	cholesterol	NOUN
dti-2185	234	2	-	-	PUNCT
dti-2185	234	3	rich	rich	ADJ
dti-2185	234	4	membrane	membrane	NOUN
dti-2185	234	5	domains	domain	NOUN
dti-2185	234	6	are	be	AUX
dti-2185	234	7	essential	essential	ADJ
dti-2185	234	8	for	for	SCONJ
dti-2185	234	9	the	the	DET
dti-2185	234	10	spike	spike	ADJ
dti-2185	234	11	proteins	protein	NOUN
dti-2185	234	12	to	to	PART
dti-2185	234	13	interact	interact	VERB
dti-2185	234	14	with	with	ADP
dti-2185	234	15	ace2	ace2	NOUN
dti-2185	234	16	receptors	receptor	NOUN
dti-2185	234	17	efficiently	efficiently	ADV
dti-2185	234	18	(	(	PUNCT
dti-2185	234	19	104	104	NUM
dti-2185	234	20	)	)	PUNCT
dti-2185	234	21	and	and	CCONJ
dti-2185	234	22	cellular	cellular	ADJ
dti-2185	234	23	cholesterol	cholesterol	NOUN
dti-2185	234	24	levels	level	NOUN
dti-2185	234	25	are	be	AUX
dti-2185	234	26	closely	closely	ADV
dti-2185	234	27	associated	associate	VERB
dti-2185	234	28	with	with	ADP
dti-2185	234	29	covid-19	covid-19	PROPN
dti-2185	234	30	lethality	lethality	NOUN
dti-2185	234	31	(	(	PUNCT
dti-2185	234	32	105	105	NUM
dti-2185	234	33	)	)	PUNCT
dti-2185	234	34	.	.	PUNCT
dti-2185	235	1	agents	agent	NOUN
dti-2185	235	2	that	that	PRON
dti-2185	235	3	specifically	specifically	ADV
dti-2185	235	4	disrupt	disrupt	VERB
dti-2185	235	5	ace2	ace2	NOUN
dti-2185	235	6	-	-	PUNCT
dti-2185	235	7	localizing	localize	VERB
dti-2185	235	8	lipid	lipid	NOUN
dti-2185	235	9	rafts	raft	NOUN
dti-2185	235	10	and	and	CCONJ
dti-2185	235	11	deplete	deplete	NOUN
dti-2185	235	12	raft	raft	NOUN
dti-2185	235	13	cholesterol	cholesterol	NOUN
dti-2185	235	14	may	may	AUX
dti-2185	235	15	be	be	AUX
dti-2185	235	16	a	a	DET
dti-2185	235	17	drug	drug	NOUN
dti-2185	235	18	to	to	PART
dti-2185	235	19	reduce	reduce	VERB
dti-2185	235	20	sars	sar	NOUN
dti-2185	235	21	-	-	PUNCT
dti-2185	235	22	cov-2	cov-2	NOUN
dti-2185	235	23	infectivity	infectivity	NOUN
dti-2185	235	24	and	and	CCONJ
dti-2185	235	25	covid-19	covid-19	PROPN
dti-2185	235	26	severity	severity	NOUN
dti-2185	235	27	.	.	PUNCT
dti-2185	236	1	abbreviations	abbreviation	NOUN
dti-2185	236	2	lo	lo	PROPN
dti-2185	236	3	,	,	PUNCT
dti-2185	236	4	liquid	liquid	NOUN
dti-2185	236	5	-	-	PUNCT
dti-2185	236	6	ordered	order	VERB
dti-2185	236	7	;	;	PUNCT
dti-2185	236	8	ld	ld	PROPN
dti-2185	236	9	,	,	PUNCT
dti-2185	236	10	liquid	liquid	NOUN
dti-2185	236	11	-	-	PUNCT
dti-2185	236	12	disordered	disorder	VERB
dti-2185	236	13	;	;	PUNCT
dti-2185	236	14	popc	popc	NOUN
dti-2185	236	15	,	,	PUNCT
dti-2185	236	16	1	1	NUM
dti-2185	236	17	-	-	PUNCT
dti-2185	236	18	palmitoyl-2	palmitoyl-2	VERB
dti-2185	236	19	-	-	PUNCT
dti-2185	236	20	oleoylphosphatidylcholine	oleoylphosphatidylcholine	NOUN
dti-2185	236	21	;	;	PUNCT
dti-2185	237	1	sm	sm	PROPN
dti-2185	237	2	,	,	PUNCT
dti-2185	237	3	sphingomyelin	sphingomyelin	NOUN
dti-2185	237	4	;	;	PUNCT
dti-2185	237	5	sdgc	sdgc	NOUN
dti-2185	237	6	,	,	PUNCT
dti-2185	237	7	sucrose	sucrose	VERB
dti-2185	237	8	density	density	NOUN
dti-2185	237	9	gradient	gradient	NOUN
dti-2185	237	10	centrifugation	centrifugation	NOUN
dti-2185	237	11	;	;	PUNCT
dti-2185	237	12	mbc	mbc	PROPN
dti-2185	237	13	,	,	PUNCT
dti-2185	237	14	methyl	methyl	NOUN
dti-2185	237	15	-	-	PUNCT
dti-2185	237	16	βcyclodextrin	βcyclodextrin	NOUN
dti-2185	237	17	;	;	PUNCT
dti-2185	237	18	fp	fp	X
dti-2185	237	19	,	,	PUNCT
dti-2185	237	20	fluorescence	fluorescence	NOUN
dti-2185	237	21	polarization	polarization	NOUN
dti-2185	237	22	;	;	PUNCT
dti-2185	237	23	fa	fa	X
dti-2185	237	24	,	,	PUNCT
dti-2185	237	25	fluorescence	fluorescence	NOUN
dti-2185	237	26	anisotropy	anisotropy	NOUN
dti-2185	237	27	;	;	PUNCT
dti-2185	237	28	dsc	dsc	NOUN
dti-2185	237	29	,	,	PUNCT
dti-2185	237	30	differential	differential	NOUN
dti-2185	237	31	scanning	scanning	NOUN
dti-2185	237	32	calorimetry	calorimetry	NOUN
dti-2185	237	33	;	;	PUNCT
dti-2185	237	34	nmr	nmr	NOUN
dti-2185	237	35	,	,	PUNCT
dti-2185	237	36	nuclear	nuclear	ADJ
dti-2185	237	37	magnetic	magnetic	ADJ
dti-2185	237	38	resonance	resonance	NOUN
dti-2185	237	39	;	;	PUNCT
dti-2185	237	40	nd	nd	NUM
dti-2185	237	41	,	,	PUNCT
dti-2185	237	42	neutron	neutron	NOUN
dti-2185	237	43	diffraction	diffraction	NOUN
dti-2185	237	44	;	;	PUNCT
dti-2185	237	45	xd	xd	ADP
dti-2185	237	46	,	,	PUNCT
dti-2185	237	47	xray	xray	PROPN
dti-2185	237	48	diffraction	diffraction	PROPN
dti-2185	237	49	;	;	PUNCT
dti-2185	237	50	gabaa	gabaa	NOUN
dti-2185	237	51	,	,	PUNCT
dti-2185	237	52	γ	γ	NOUN
dti-2185	237	53	-	-	ADJ
dti-2185	237	54	aminobutyric	aminobutyric	ADJ
dti-2185	237	55	acid	acid	NOUN
dti-2185	237	56	type	type	NOUN
dti-2185	237	57	a	a	DET
dti-2185	237	58	;	;	PUNCT
dti-2185	237	59	nmda	nmda	ADJ
dti-2185	237	60	,	,	PUNCT
dti-2185	237	61	n	n	CCONJ
dti-2185	237	62	-	-	PUNCT
dti-2185	237	63	methyl	methyl	NOUN
dti-2185	237	64	-	-	PUNCT
dti-2185	237	65	d	d	NOUN
dti-2185	237	66	-	-	NOUN
dti-2185	237	67	aspartate	aspartate	NOUN
dti-2185	237	68	;	;	PUNCT
dti-2185	237	69	pope	pope	NOUN
dti-2185	237	70	,	,	PUNCT
dti-2185	237	71	1	1	NUM
dti-2185	237	72	-	-	PUNCT
dti-2185	237	73	palmitoyl-2	palmitoyl-2	VERB
dti-2185	237	74	-	-	PUNCT
dti-2185	237	75	oleoylphosphatidylethanolamine	oleoylphosphatidylethanolamine	NOUN
dti-2185	237	76	;	;	PUNCT
dti-2185	237	77	pops	pop	NOUN
dti-2185	237	78	,	,	PUNCT
dti-2185	237	79	1	1	NUM
dti-2185	237	80	-	-	PUNCT
dti-2185	237	81	palmitoyl-2	palmitoyl-2	VERB
dti-2185	237	82	-	-	PUNCT
dti-2185	237	83	oleoylphosphatidylserine	oleoylphosphatidylserine	ADJ
dti-2185	237	84	;	;	PUNCT
dti-2185	237	85	gpmv	gpmv	X
dti-2185	237	86	,	,	PUNCT
dti-2185	237	87	giant	giant	ADJ
dti-2185	237	88	plasma	plasma	NOUN
dti-2185	237	89	membrane	membrane	NOUN
dti-2185	237	90	vesicle	vesicle	NOUN
dti-2185	237	91	;	;	PUNCT
dti-2185	237	92	luv	luv	PROPN
dti-2185	237	93	,	,	PUNCT
dti-2185	237	94	large	large	ADJ
dti-2185	237	95	unilamellar	unilamellar	ADJ
dti-2185	237	96	vesicle	vesicle	NOUN
dti-2185	237	97	;	;	PUNCT
dti-2185	237	98	dppc	dppc	NOUN
dti-2185	237	99	,	,	PUNCT
dti-2185	237	100	1,2	1,2	NUM
dti-2185	237	101	-	-	NUM
dti-2185	237	102	dipalmitoylphosphatidylcholine	dipalmitoylphosphatidylcholine	ADJ
dti-2185	237	103	;	;	PUNCT
dti-2185	237	104	dlpc	dlpc	NOUN
dti-2185	237	105	,	,	PUNCT
dti-2185	237	106	1,2	1,2	NUM
dti-2185	237	107	-	-	NUM
dti-2185	237	108	dilauroylphosphatidylcholine	dilauroylphosphatidylcholine	ADJ
dti-2185	237	109	;	;	PUNCT
dti-2185	237	110	mac	mac	NOUN
dti-2185	237	111	,	,	PUNCT
dti-2185	237	112	minimum	minimum	ADJ
dti-2185	237	113	alveolar	alveolar	ADJ
dti-2185	237	114	concentration	concentration	NOUN
dti-2185	237	115	;	;	PUNCT
dti-2185	237	116	dopc	dopc	NOUN
dti-2185	237	117	,	,	PUNCT
dti-2185	237	118	1,2	1,2	NUM
dti-2185	237	119	-	-	NOUN
dti-2185	237	120	dioleoylphosphatidylcholine	dioleoylphosphatidylcholine	NOUN
dti-2185	237	121	;	;	PUNCT
dti-2185	237	122	nav	nav	NOUN
dti-2185	237	123	,	,	PUNCT
dti-2185	237	124	voltage	voltage	NOUN
dti-2185	237	125	-	-	PUNCT
dti-2185	237	126	gated	gate	VERB
dti-2185	237	127	sodium	sodium	NOUN
dti-2185	237	128	;	;	PUNCT
dti-2185	237	129	suv	suv	PROPN
dti-2185	237	130	,	,	PUNCT
dti-2185	237	131	small	small	ADJ
dti-2185	237	132	unilamellar	unilamellar	ADJ
dti-2185	237	133	vesicle	vesicle	NOUN
dti-2185	237	134	;	;	PUNCT
dti-2185	237	135	cb	cb	PROPN
dti-2185	237	136	,	,	PUNCT
dti-2185	237	137	cerebroside	cerebroside	PROPN
dti-2185	237	138	;	;	PUNCT
dti-2185	237	139	popi	popi	PROPN
dti-2185	237	140	,	,	PUNCT
dti-2185	237	141	1	1	NUM
dti-2185	237	142	-	-	PUNCT
dti-2185	237	143	palmitoyl-2	palmitoyl-2	VERB
dti-2185	237	144	-	-	PUNCT
dti-2185	237	145	oleoylphosphatidylinositol	oleoylphosphatidylinositol	ADJ
dti-2185	237	146	;	;	PUNCT
dti-2185	237	147	mlv	mlv	PROPN
dti-2185	237	148	,	,	PUNCT
dti-2185	237	149	multilamellar	multilamellar	ADJ
dti-2185	237	150	vesicle	vesicle	NOUN
dti-2185	237	151	;	;	PUNCT
dti-2185	237	152	epr	epr	PROPN
dti-2185	237	153	,	,	PUNCT
dti-2185	237	154	electron	electron	NOUN
dti-2185	237	155	paramagnetic	paramagnetic	ADJ
dti-2185	237	156	resonance	resonance	NOUN
dti-2185	237	157	;	;	PUNCT
dti-2185	237	158	cox	cox	PROPN
dti-2185	237	159	,	,	PUNCT
dti-2185	237	160	cyclooxygenase	cyclooxygenase	PROPN
dti-2185	237	161	;	;	PUNCT
dti-2185	237	162	dmpc	dmpc	NOUN
dti-2185	237	163	,	,	PUNCT
dti-2185	237	164	1,2	1,2	NUM
dti-2185	237	165	-	-	NUM
dti-2185	237	166	dimyristoylphosphatidylcholine	dimyristoylphosphatidylcholine	NOUN
dti-2185	237	167	;	;	PUNCT
dti-2185	237	168	odpc	odpc	ADV
dti-2185	237	169	,	,	PUNCT
dti-2185	237	170	10-(octyloxy	10-(octyloxy	NUM
dti-2185	237	171	)	)	PUNCT
dti-2185	237	172	decyl-2-(trimethylammonium	decyl-2-(trimethylammonium	NOUN
dti-2185	237	173	)	)	PUNCT
dti-2185	237	174	ethyl	ethyl	PROPN
dti-2185	237	175	phosphate	phosphate	NOUN
dti-2185	237	176	;	;	PUNCT
dti-2185	237	177	guv	guv	NOUN
dti-2185	237	178	,	,	PUNCT
dti-2185	237	179	giant	giant	ADJ
dti-2185	237	180	unilamellar	unilamellar	ADJ
dti-2185	237	181	vesicle	vesicle	NOUN
dti-2185	237	182	;	;	PUNCT
dti-2185	237	183	ulv	ulv	NOUN
dti-2185	237	184	,	,	PUNCT
dti-2185	237	185	unilamellar	unilamellar	ADJ
dti-2185	237	186	vesicle	vesicle	NOUN
dti-2185	237	187	;	;	PUNCT
dti-2185	237	188	egcg	egcg	NOUN
dti-2185	237	189	,	,	PUNCT
dti-2185	237	190	(	(	PUNCT
dti-2185	237	191	–	–	PUNCT
dti-2185	237	192	)	)	PUNCT
dti-2185	237	193	epigallocatechin-3	epigallocatechin-3	PROPN
dti-2185	237	194	-	-	NOUN
dti-2185	237	195	gallate	gallate	NOUN
dti-2185	237	196	;	;	PUNCT
dti-2185	237	197	tnf	tnf	PROPN
dti-2185	237	198	,	,	PUNCT
dti-2185	237	199	tumor	tumor	NOUN
dti-2185	237	200	necrosis	necrosis	NOUN
dti-2185	237	201	factor	factor	NOUN
dti-2185	237	202	;	;	PUNCT
dti-2185	237	203	trail	trail	NOUN
dti-2185	237	204	,	,	PUNCT
dti-2185	237	205	tnf	tnf	PROPN
dti-2185	237	206	-	-	PUNCT
dti-2185	237	207	related	relate	VERB
dti-2185	237	208	apoptosis	apoptosis	NOUN
dti-2185	237	209	-	-	PUNCT
dti-2185	237	210	inducing	induce	VERB
dti-2185	237	211	ligand	ligand	NOUN
dti-2185	237	212	;	;	PUNCT
dti-2185	237	213	lps	lps	PROPN
dti-2185	237	214	,	,	PUNCT
dti-2185	237	215	lipopolysaccharide	lipopolysaccharide	PROPN
dti-2185	237	216	;	;	PUNCT
dti-2185	237	217	sars	sar	NOUN
dti-2185	237	218	-	-	PUNCT
dti-2185	237	219	cov-2	cov-2	NOUN
dti-2185	237	220	,	,	PUNCT
dti-2185	237	221	severe	severe	ADJ
dti-2185	237	222	acute	acute	ADJ
dti-2185	237	223	respiratory	respiratory	ADJ
dti-2185	237	224	syndrome	syndrome	NOUN
dti-2185	237	225	coronavirus	coronavirus	NOUN
dti-2185	237	226	2	2	NUM
dti-2185	237	227	;	;	PUNCT
dti-2185	237	228	covid-19	covid-19	PROPN
dti-2185	237	229	,	,	PUNCT
dti-2185	237	230	coronavirus	coronavirus	NOUN
dti-2185	237	231	disease	disease	NOUN
dti-2185	237	232	2019	2019	NUM
dti-2185	237	233	;	;	PUNCT
dti-2185	237	234	ace2	ace2	NOUN
dti-2185	237	235	,	,	PUNCT
dti-2185	237	236	angiotensin	angiotensin	NOUN
dti-2185	237	237	-	-	PUNCT
dti-2185	237	238	converting	convert	VERB
dti-2185	237	239	enzyme	enzyme	NOUN
dti-2185	237	240	2	2	NUM
dti-2185	237	241	.	.	PUNCT
dti-2185	238	1	author	author	NOUN
dti-2185	238	2	contributions	contribution	NOUN
dti-2185	238	3	ht	ht	PROPN
dti-2185	238	4	designed	design	VERB
dti-2185	238	5	and	and	CCONJ
dti-2185	238	6	conducted	conduct	VERB
dti-2185	238	7	the	the	DET
dti-2185	238	8	present	present	ADJ
dti-2185	238	9	study	study	NOUN
dti-2185	238	10	and	and	CCONJ
dti-2185	238	11	prepared	prepare	VERB
dti-2185	238	12	the	the	DET
dti-2185	238	13	first	first	ADJ
dti-2185	238	14	draft	draft	NOUN
dti-2185	238	15	of	of	ADP
dti-2185	238	16	the	the	DET
dti-2185	238	17	manuscript	manuscript	NOUN
dti-2185	238	18	.	.	PUNCT
dti-2185	239	1	ht	ht	PROPN
dti-2185	240	1	and	and	CCONJ
dti-2185	240	2	mm	mm	PROPN
dti-2185	240	3	did	do	VERB
dti-2185	240	4	literature	literature	NOUN
dti-2185	240	5	search	search	NOUN
dti-2185	240	6	,	,	PUNCT
dti-2185	240	7	information	information	NOUN
dti-2185	240	8	analysis	analysis	NOUN
dti-2185	240	9	and	and	CCONJ
dti-2185	240	10	manuscript	manuscript	NOUN
dti-2185	240	11	preparation	preparation	NOUN
dti-2185	240	12	.	.	PUNCT
dti-2185	241	1	both	both	DET
dti-2185	241	2	authors	author	NOUN
dti-2185	241	3	reviewed	review	VERB
dti-2185	241	4	and	and	CCONJ
dti-2185	241	5	approved	approve	VERB
dti-2185	241	6	the	the	DET
dti-2185	241	7	final	final	ADJ
dti-2185	241	8	manuscript	manuscript	NOUN
dti-2185	241	9	.	.	PUNCT
dti-2185	242	1	disclosures	disclosure	VERB
dti-2185	242	2	conflict	conflict	NOUN
dti-2185	242	3	of	of	ADP
dti-2185	242	4	interest	interest	NOUN
dti-2185	242	5	:	:	PUNCT
dti-2185	242	6	authors	author	NOUN
dti-2185	242	7	disclose	disclose	VERB
dti-2185	242	8	no	no	DET
dti-2185	242	9	potential	potential	ADJ
dti-2185	242	10	conflicts	conflict	NOUN
dti-2185	242	11	of	of	ADP
dti-2185	242	12	interest	interest	NOUN
dti-2185	242	13	.	.	PUNCT
dti-2185	243	1	financial	financial	ADJ
dti-2185	243	2	support	support	NOUN
dti-2185	243	3	:	:	PUNCT
dti-2185	243	4	this	this	DET
dti-2185	243	5	study	study	NOUN
dti-2185	243	6	was	be	AUX
dti-2185	243	7	supported	support	VERB
dti-2185	243	8	by	by	ADP
dti-2185	243	9	jsps	jsps	PROPN
dti-2185	243	10	kakenhi	kakenhi	PROPN
dti-2185	243	11	grant	grant	PROPN
dti-2185	243	12	number	number	NOUN
dti-2185	243	13	20k10152	20k10152	PROPN
dti-2185	243	14	and	and	CCONJ
dti-2185	243	15	jsps	jsps	PROPN
dti-2185	243	16	kakenhi	kakenhi	PROPN
dti-2185	243	17	grant	grant	PROPN
dti-2185	243	18	number	number	NOUN
dti-2185	243	19	17k11924	17k11924	NUM
dti-2185	243	20	.	.	PUNCT
dti-2185	244	1	references	reference	NOUN
dti-2185	244	2	1	1	NUM
dti-2185	244	3	.	.	PUNCT
dti-2185	244	4	kusumi	kusumi	PROPN
dti-2185	244	5	a	a	PROPN
dti-2185	244	6	,	,	PUNCT
dti-2185	244	7	fujiwara	fujiwara	PROPN
dti-2185	244	8	tk	tk	PROPN
dti-2185	244	9	,	,	PUNCT
dti-2185	244	10	chadda	chadda	NOUN
dti-2185	244	11	r	r	NOUN
dti-2185	244	12	,	,	PUNCT
dti-2185	244	13	et	et	PROPN
dti-2185	244	14	al	al	PROPN
dti-2185	244	15	.	.	PUNCT
dti-2185	244	16	dynamic	dynamic	ADJ
dti-2185	244	17	organizing	organizing	NOUN
dti-2185	244	18	principles	principle	NOUN
dti-2185	244	19	of	of	ADP
dti-2185	244	20	the	the	DET
dti-2185	244	21	plasma	plasma	NOUN
dti-2185	244	22	membrane	membrane	NOUN
dti-2185	244	23	that	that	PRON
dti-2185	244	24	regulate	regulate	VERB
dti-2185	244	25	signal	signal	NOUN
dti-2185	244	26	transduction	transduction	NOUN
dti-2185	244	27	:	:	PUNCT
dti-2185	244	28	commemorating	commemorate	VERB
dti-2185	244	29	the	the	DET
dti-2185	244	30	fortieth	fortieth	ADJ
dti-2185	244	31	anniversary	anniversary	NOUN
dti-2185	244	32	of	of	ADP
dti-2185	244	33	singer	singer	NOUN
dti-2185	244	34	and	and	CCONJ
dti-2185	244	35	nicolson	nicolson	PROPN
dti-2185	244	36	’s	’s	PART
dti-2185	244	37	fluid	fluid	ADJ
dti-2185	244	38	-	-	PUNCT
dti-2185	244	39	mosaic	mosaic	ADJ
dti-2185	244	40	model	model	NOUN
dti-2185	244	41	.	.	PUNCT
dti-2185	245	1	annu	annu	PROPN
dti-2185	245	2	rev	rev	PROPN
dti-2185	245	3	cell	cell	PROPN
dti-2185	245	4	dev	dev	PROPN
dti-2185	245	5	biol	biol	NOUN
dti-2185	245	6	.	.	PUNCT
dti-2185	246	1	2012;28(1):215	2012;28(1):215	NUM
dti-2185	246	2	-	-	SYM
dti-2185	246	3	250	250	NUM
dti-2185	246	4	.	.	PUNCT
dti-2185	247	1	crossref	crossref	PROPN
dti-2185	247	2	medline	medline	NOUN
dti-2185	247	3	2	2	NUM
dti-2185	247	4	.	.	PUNCT
dti-2185	248	1	pike	pike	PROPN
dti-2185	248	2	lj	lj	PROPN
dti-2185	248	3	.	.	PUNCT
dti-2185	249	1	rafts	raft	NOUN
dti-2185	249	2	defined	define	VERB
dti-2185	249	3	:	:	PUNCT
dti-2185	249	4	a	a	DET
dti-2185	249	5	report	report	NOUN
dti-2185	249	6	on	on	ADP
dti-2185	249	7	the	the	DET
dti-2185	249	8	keystone	keystone	PROPN
dti-2185	249	9	symposium	symposium	NOUN
dti-2185	249	10	on	on	ADP
dti-2185	249	11	lipid	lipid	ADJ
dti-2185	249	12	rafts	raft	NOUN
dti-2185	249	13	and	and	CCONJ
dti-2185	249	14	cell	cell	NOUN
dti-2185	249	15	function	function	NOUN
dti-2185	249	16	.	.	PUNCT
dti-2185	250	1	j	j	PROPN
dti-2185	250	2	lipid	lipid	PROPN
dti-2185	250	3	res	re	NOUN
dti-2185	250	4	.	.	PUNCT
dti-2185	251	1	2006;47(7):1597	2006;47(7):1597	NUM
dti-2185	251	2	-	-	SYM
dti-2185	251	3	1598	1598	NUM
dti-2185	251	4	.	.	PUNCT
dti-2185	252	1	crossref	crossref	PROPN
dti-2185	252	2	medline	medline	NOUN
dti-2185	252	3	3	3	NUM
dti-2185	252	4	.	.	PUNCT
dti-2185	252	5	hanzal	hanzal	PROPN
dti-2185	252	6	-	-	PUNCT
dti-2185	252	7	bayer	bayer	PROPN
dti-2185	252	8	mf	mf	PROPN
dti-2185	252	9	,	,	PUNCT
dti-2185	252	10	hancock	hancock	PROPN
dti-2185	252	11	jf	jf	PROPN
dti-2185	252	12	.	.	PROPN
dti-2185	252	13	lipid	lipid	PROPN
dti-2185	252	14	rafts	raft	NOUN
dti-2185	252	15	and	and	CCONJ
dti-2185	252	16	membrane	membrane	NOUN
dti-2185	252	17	traffic	traffic	NOUN
dti-2185	252	18	.	.	PUNCT
dti-2185	253	1	febs	febs	PROPN
dti-2185	253	2	lett	lett	PROPN
dti-2185	253	3	.	.	PUNCT
dti-2185	254	1	2007;581(11):2098	2007;581(11):2098	NUM
dti-2185	254	2	-	-	SYM
dti-2185	254	3	2104	2104	NUM
dti-2185	254	4	.	.	PUNCT
dti-2185	255	1	crossref	crossref	PROPN
dti-2185	255	2	medline	medline	PROPN
dti-2185	255	3	4	4	NUM
dti-2185	255	4	.	.	PUNCT
dti-2185	256	1	mcmullen	mcmullen	PROPN
dti-2185	256	2	t	t	PROPN
dti-2185	256	3	,	,	PUNCT
dti-2185	256	4	lewis	lewis	PROPN
dti-2185	256	5	r	r	PROPN
dti-2185	256	6	,	,	PUNCT
dti-2185	256	7	mcelhany	mcelhany	VERB
dti-2185	256	8	r.	r.	PROPN
dti-2185	256	9	cholesterol	cholesterol	NOUN
dti-2185	256	10	-	-	PUNCT
dti-2185	256	11	phospholipid	phospholipid	NOUN
dti-2185	256	12	interactions	interaction	NOUN
dti-2185	256	13	,	,	PUNCT
dti-2185	256	14	the	the	DET
dti-2185	256	15	liquid	liquid	NOUN
dti-2185	256	16	-	-	PUNCT
dti-2185	256	17	ordered	order	VERB
dti-2185	256	18	phase	phase	NOUN
dti-2185	256	19	and	and	CCONJ
dti-2185	256	20	lipid	lipid	NOUN
dti-2185	256	21	rafts	raft	NOUN
dti-2185	256	22	in	in	ADP
dti-2185	256	23	model	model	NOUN
dti-2185	256	24	and	and	CCONJ
dti-2185	256	25	biological	biological	ADJ
dti-2185	256	26	membranes	membrane	NOUN
dti-2185	256	27	.	.	PUNCT
dti-2185	257	1	curr	curr	PROPN
dti-2185	257	2	opin	opin	NOUN
dti-2185	257	3	colloid	colloid	PROPN
dti-2185	257	4	interface	interface	NOUN
dti-2185	257	5	sci	sci	PROPN
dti-2185	257	6	.	.	PUNCT
dti-2185	257	7	2004;8(6):459	2004;8(6):459	NUM
dti-2185	257	8	-	-	NOUN
dti-2185	257	9	468	468	NUM
dti-2185	257	10	.	.	PUNCT
dti-2185	258	1	crossref	crossref	PROPN
dti-2185	258	2	5	5	NUM
dti-2185	258	3	.	.	PUNCT
dti-2185	259	1	simons	simons	PROPN
dti-2185	259	2	k	k	PROPN
dti-2185	259	3	,	,	PUNCT
dti-2185	259	4	toomre	toomre	PROPN
dti-2185	259	5	d.	d.	PROPN
dti-2185	259	6	lipid	lipid	PROPN
dti-2185	259	7	rafts	raft	NOUN
dti-2185	259	8	and	and	CCONJ
dti-2185	259	9	signal	signal	ADJ
dti-2185	259	10	transduction	transduction	NOUN
dti-2185	259	11	.	.	PUNCT
dti-2185	260	1	nat	nat	PROPN
dti-2185	260	2	rev	rev	VERB
dti-2185	260	3	mol	mol	ADP
dti-2185	260	4	cell	cell	NOUN
dti-2185	260	5	biol	biol	NOUN
dti-2185	260	6	.	.	PUNCT
dti-2185	261	1	2000;1(1):31	2000;1(1):31	NUM
dti-2185	261	2	-	-	SYM
dti-2185	261	3	39	39	NUM
dti-2185	261	4	.	.	PUNCT
dti-2185	262	1	crossref	crossref	PROPN
dti-2185	262	2	medline	medline	PROPN
dti-2185	262	3	6	6	NUM
dti-2185	262	4	.	.	PUNCT
dti-2185	263	1	laude	laude	PROPN
dti-2185	263	2	aj	aj	PROPN
dti-2185	263	3	,	,	PUNCT
dti-2185	263	4	prior	prior	ADV
dti-2185	263	5	ia	ia	PROPN
dti-2185	263	6	.	.	PROPN
dti-2185	263	7	plasma	plasma	NOUN
dti-2185	263	8	membrane	membrane	NOUN
dti-2185	263	9	microdomains	microdomain	NOUN
dti-2185	263	10	:	:	PUNCT
dti-2185	263	11	organization	organization	NOUN
dti-2185	263	12	,	,	PUNCT
dti-2185	263	13	function	function	NOUN
dti-2185	263	14	and	and	CCONJ
dti-2185	263	15	trafficking	trafficking	NOUN
dti-2185	263	16	.	.	PUNCT
dti-2185	264	1	mol	mol	ADP
dti-2185	264	2	membr	membr	NOUN
dti-2185	264	3	biol	biol	PROPN
dti-2185	264	4	.	.	PUNCT
dti-2185	265	1	2004;21(3):193205	2004;21(3):193205	NUM
dti-2185	265	2	.	.	PUNCT
dti-2185	265	3	crossref	crossref	PROPN
dti-2185	265	4	medline	medline	PROPN
dti-2185	265	5	7	7	X
dti-2185	265	6	.	.	PUNCT
dti-2185	265	7	george	george	PROPN
dti-2185	265	8	ks	ks	PROPN
dti-2185	265	9	,	,	PUNCT
dti-2185	265	10	wu	wu	PROPN
dti-2185	265	11	s.	s.	PROPN
dti-2185	265	12	lipid	lipid	PROPN
dti-2185	265	13	raft	raft	PROPN
dti-2185	265	14	:	:	PUNCT
dti-2185	265	15	a	a	DET
dti-2185	265	16	floating	float	VERB
dti-2185	265	17	island	island	NOUN
dti-2185	265	18	of	of	ADP
dti-2185	265	19	death	death	NOUN
dti-2185	265	20	or	or	CCONJ
dti-2185	265	21	survival	survival	NOUN
dti-2185	265	22	.	.	PUNCT
dti-2185	266	1	toxicol	toxicol	PROPN
dti-2185	266	2	appl	appl	PROPN
dti-2185	266	3	pharmacol	pharmacol	PROPN
dti-2185	266	4	.	.	PUNCT
dti-2185	267	1	2012;259(3):311	2012;259(3):311	NUM
dti-2185	267	2	-	-	SYM
dti-2185	267	3	319	319	NUM
dti-2185	267	4	.	.	PUNCT
dti-2185	267	5	crossref	crossref	PROPN
dti-2185	267	6	medline	medline	PROPN
dti-2185	267	7	8	8	NUM
dti-2185	267	8	.	.	PUNCT
dti-2185	268	1	o’connell	o’connell	INTJ
dti-2185	268	2	km	km	PROPN
dti-2185	268	3	,	,	PUNCT
dti-2185	268	4	martens	martens	PROPN
dti-2185	268	5	jr	jr	PROPN
dti-2185	268	6	,	,	PUNCT
dti-2185	268	7	tamkun	tamkun	PROPN
dti-2185	268	8	mm	mm	INTJ
dti-2185	268	9	.	.	PUNCT
dti-2185	269	1	localization	localization	NOUN
dti-2185	269	2	of	of	ADP
dti-2185	269	3	ion	ion	NOUN
dti-2185	269	4	channels	channel	NOUN
dti-2185	269	5	to	to	ADP
dti-2185	269	6	lipid	lipid	NOUN
dti-2185	269	7	raft	raft	NOUN
dti-2185	269	8	domains	domain	NOUN
dti-2185	269	9	within	within	ADP
dti-2185	269	10	the	the	DET
dti-2185	269	11	cardiovascular	cardiovascular	ADJ
dti-2185	269	12	system	system	NOUN
dti-2185	269	13	.	.	PUNCT
dti-2185	270	1	trends	trend	NOUN
dti-2185	270	2	cardiovasc	cardiovasc	PROPN
dti-2185	270	3	med	me	VERB
dti-2185	270	4	.	.	PUNCT
dti-2185	271	1	2004;14(2):37	2004;14(2):37	NUM
dti-2185	271	2	-	-	SYM
dti-2185	271	3	42	42	NUM
dti-2185	271	4	.	.	PUNCT
dti-2185	272	1	crossref	crossref	PROPN
dti-2185	272	2	medline	medline	PROPN
dti-2185	272	3	https://doi.org/10.1146/annurev-cellbio-100809-151736	https://doi.org/10.1146/annurev-cellbio-100809-151736	PROPN
dti-2185	272	4	https://www.ncbi.nlm.nih.gov/pubmed/22905956	https://www.ncbi.nlm.nih.gov/pubmed/22905956	PRON
dti-2185	273	1	https://doi.org/10.1194/jlr.e600002-jlr200	https://doi.org/10.1194/jlr.e600002-jlr200	PRON
dti-2185	273	2	https://www.ncbi.nlm.nih.gov/pubmed/16645198	https://www.ncbi.nlm.nih.gov/pubmed/16645198	NUM
dti-2185	273	3	https://doi.org/10.1016/j.febslet.2007.03.019	https://doi.org/10.1016/j.febslet.2007.03.019	PROPN
dti-2185	273	4	https://www.ncbi.nlm.nih.gov/pubmed/17382322	https://www.ncbi.nlm.nih.gov/pubmed/17382322	PRON
dti-2185	273	5	https://doi.org/10.1016/j.cocis.2004.01.007	https://doi.org/10.1016/j.cocis.2004.01.007	VERB
dti-2185	273	6	https://doi.org/10.1038/35036052	https://doi.org/10.1038/35036052	PRON
dti-2185	273	7	https://www.ncbi.nlm.nih.gov/pubmed/11413487	https://www.ncbi.nlm.nih.gov/pubmed/11413487	X
dti-2185	273	8	https://doi.org/10.1080/09687680410001700517	https://doi.org/10.1080/09687680410001700517	X
dti-2185	273	9	https://www.ncbi.nlm.nih.gov/pubmed/15204627	https://www.ncbi.nlm.nih.gov/pubmed/15204627	X
dti-2185	273	10	https://doi.org/10.1016/j.taap.2012.01.007	https://doi.org/10.1016/j.taap.2012.01.007	PROPN
dti-2185	273	11	https://www.ncbi.nlm.nih.gov/pubmed/22289360	https://www.ncbi.nlm.nih.gov/pubmed/22289360	NOUN
dti-2185	273	12	https://doi.org/10.1016/j.tcm.2003.10.002	https://doi.org/10.1016/j.tcm.2003.10.002	PRON
dti-2185	273	13	https://www.ncbi.nlm.nih.gov/pubmed/15030787	https://www.ncbi.nlm.nih.gov/pubmed/15030787	X
dti-2185	273	14	tsuchiya	tsuchiya	PROPN
dti-2185	273	15	and	and	CCONJ
dti-2185	273	16	mizogami	mizogami	PROPN
dti-2185	273	17	45	45	NUM
dti-2185	274	1	©	©	PROPN
dti-2185	274	2	2020	2020	NUM
dti-2185	274	3	the	the	DET
dti-2185	274	4	authors	author	NOUN
dti-2185	274	5	.	.	PUNCT
dti-2185	275	1	published	publish	VERB
dti-2185	275	2	by	by	ADP
dti-2185	275	3	aboutscience	aboutscience	NOUN
dti-2185	275	4	9	9	NUM
dti-2185	275	5	.	.	PUNCT
dti-2185	275	6	maguy	maguy	PROPN
dti-2185	275	7	a	a	PROPN
dti-2185	275	8	,	,	PUNCT
dti-2185	275	9	hebert	hebert	NOUN
dti-2185	275	10	te	te	PROPN
dti-2185	275	11	,	,	PUNCT
dti-2185	275	12	nattel	nattel	PROPN
dti-2185	275	13	s.	s.	PROPN
dti-2185	275	14	involvement	involvement	PROPN
dti-2185	275	15	of	of	ADP
dti-2185	275	16	lipid	lipid	ADJ
dti-2185	275	17	rafts	raft	NOUN
dti-2185	275	18	and	and	CCONJ
dti-2185	275	19	caveolae	caveolae	NOUN
dti-2185	275	20	in	in	ADP
dti-2185	275	21	cardiac	cardiac	ADJ
dti-2185	275	22	ion	ion	NOUN
dti-2185	275	23	channel	channel	NOUN
dti-2185	275	24	function	function	NOUN
dti-2185	275	25	.	.	PUNCT
dti-2185	276	1	cardiovasc	cardiovasc	PROPN
dti-2185	276	2	res	res	PROPN
dti-2185	276	3	.	.	PUNCT
dti-2185	277	1	2006;69(4):798	2006;69(4):798	NUM
dti-2185	277	2	-	-	PUNCT
dti-2185	277	3	807	807	NUM
dti-2185	277	4	.	.	PUNCT
dti-2185	277	5	crossref	crossref	PROPN
dti-2185	277	6	medline	medline	PROPN
dti-2185	277	7	10	10	NUM
dti-2185	277	8	.	.	PUNCT
dti-2185	278	1	dalskov	dalskov	PROPN
dti-2185	278	2	sm	sm	PROPN
dti-2185	278	3	,	,	PUNCT
dti-2185	278	4	immerdal	immerdal	ADJ
dti-2185	278	5	l	l	NOUN
dti-2185	278	6	,	,	PUNCT
dti-2185	278	7	niels	niel	NOUN
dti-2185	278	8	-	-	PUNCT
dti-2185	278	9	christiansen	christiansen	PROPN
dti-2185	278	10	ll	ll	PROPN
dti-2185	278	11	,	,	PUNCT
dti-2185	278	12	hansen	hansen	PROPN
dti-2185	278	13	gh	gh	PROPN
dti-2185	278	14	,	,	PUNCT
dti-2185	278	15	schousboe	schousboe	VERB
dti-2185	278	16	a	a	PRON
dti-2185	278	17	,	,	PUNCT
dti-2185	278	18	danielsen	danielsen	VERB
dti-2185	278	19	em	em	PRON
dti-2185	278	20	.	.	PUNCT
dti-2185	279	1	lipid	lipid	NOUN
dti-2185	279	2	raft	raft	NOUN
dti-2185	279	3	localization	localization	NOUN
dti-2185	279	4	of	of	ADP
dti-2185	279	5	gabaa	gabaa	NOUN
dti-2185	279	6	receptor	receptor	NOUN
dti-2185	279	7	and	and	CCONJ
dti-2185	279	8	na+	na+	NOUN
dti-2185	279	9	,	,	PUNCT
dti-2185	279	10	k+-atpase	k+-atpase	NOUN
dti-2185	279	11	in	in	ADP
dti-2185	279	12	discrete	discrete	ADJ
dti-2185	279	13	microdomain	microdomain	NOUN
dti-2185	279	14	clusters	cluster	NOUN
dti-2185	279	15	in	in	ADP
dti-2185	279	16	rat	rat	NOUN
dti-2185	279	17	cerebellar	cerebellar	ADJ
dti-2185	279	18	granule	granule	NOUN
dti-2185	279	19	cells	cell	NOUN
dti-2185	279	20	.	.	PUNCT
dti-2185	280	1	neurochem	neurochem	PROPN
dti-2185	280	2	int	int	NOUN
dti-2185	280	3	.	.	PUNCT
dti-2185	281	1	2005;46(6):489499	2005;46(6):489499	NUM
dti-2185	281	2	.	.	PUNCT
dti-2185	282	1	crossref	crossref	PROPN
dti-2185	282	2	medline	medline	PROPN
dti-2185	282	3	11	11	NUM
dti-2185	282	4	.	.	PUNCT
dti-2185	283	1	patel	patel	PROPN
dti-2185	283	2	hh	hh	PROPN
dti-2185	283	3	,	,	PUNCT
dti-2185	283	4	murray	murray	PROPN
dti-2185	283	5	f	f	PROPN
dti-2185	283	6	,	,	PUNCT
dti-2185	283	7	insel	insel	PROPN
dti-2185	283	8	pa	pa	PROPN
dti-2185	283	9	.	.	PROPN
dti-2185	284	1	g	g	NOUN
dti-2185	284	2	-	-	PUNCT
dti-2185	284	3	protein	protein	NOUN
dti-2185	284	4	-	-	PUNCT
dti-2185	284	5	coupled	couple	VERB
dti-2185	284	6	receptor	receptor	NOUN
dti-2185	284	7	-	-	PUNCT
dti-2185	284	8	signaling	signal	VERB
dti-2185	284	9	components	component	NOUN
dti-2185	284	10	in	in	ADP
dti-2185	284	11	membrane	membrane	NOUN
dti-2185	284	12	raft	raft	NOUN
dti-2185	284	13	and	and	CCONJ
dti-2185	284	14	caveolae	caveolae	NOUN
dti-2185	284	15	microdomains	microdomain	NOUN
dti-2185	284	16	.	.	PUNCT
dti-2185	285	1	handb	handb	NOUN
dti-2185	285	2	exp	exp	NOUN
dti-2185	285	3	pharmacol	pharmacol	NOUN
dti-2185	285	4	.	.	PUNCT
dti-2185	286	1	2008;186(186):167	2008;186(186):167	NUM
dti-2185	286	2	-	-	SYM
dti-2185	286	3	184	184	NUM
dti-2185	286	4	.	.	PUNCT
dti-2185	286	5	crossref	crossref	PROPN
dti-2185	286	6	medline	medline	PROPN
dti-2185	286	7	12	12	NUM
dti-2185	286	8	.	.	PUNCT
dti-2185	287	1	xiang	xiang	PROPN
dti-2185	287	2	y	y	PROPN
dti-2185	287	3	,	,	PUNCT
dti-2185	287	4	rybin	rybin	PROPN
dti-2185	287	5	vo	vo	PROPN
dti-2185	287	6	,	,	PUNCT
dti-2185	287	7	steinberg	steinberg	PROPN
dti-2185	287	8	sf	sf	PROPN
dti-2185	287	9	,	,	PUNCT
dti-2185	287	10	kobilka	kobilka	PROPN
dti-2185	287	11	b.	b.	PROPN
dti-2185	288	1	caveolar	caveolar	ADJ
dti-2185	288	2	localization	localization	NOUN
dti-2185	288	3	dictates	dictate	VERB
dti-2185	288	4	physiologic	physiologic	ADJ
dti-2185	288	5	signaling	signal	VERB
dti-2185	288	6	of	of	ADP
dti-2185	288	7	β2	β2	NOUN
dti-2185	288	8	-	-	PUNCT
dti-2185	288	9	adrenoceptors	adrenoceptor	NOUN
dti-2185	288	10	in	in	ADP
dti-2185	288	11	neonatal	neonatal	ADJ
dti-2185	288	12	cardiac	cardiac	ADJ
dti-2185	288	13	myocytes	myocyte	NOUN
dti-2185	288	14	.	.	PUNCT
dti-2185	289	1	j	j	PROPN
dti-2185	289	2	biol	biol	PROPN
dti-2185	289	3	chem	chem	NOUN
dti-2185	289	4	.	.	PUNCT
dti-2185	290	1	2002;277(37):34280	2002;277(37):34280	NUM
dti-2185	290	2	-	-	SYM
dti-2185	290	3	34286	34286	NUM
dti-2185	290	4	.	.	PUNCT
dti-2185	291	1	crossref	crossref	PROPN
dti-2185	291	2	medline	medline	PROPN
dti-2185	291	3	13	13	NUM
dti-2185	291	4	.	.	PUNCT
dti-2185	292	1	pottosin	pottosin	PROPN
dti-2185	292	2	ii	ii	PROPN
dti-2185	292	3	,	,	PUNCT
dti-2185	292	4	valencia	valencia	PROPN
dti-2185	292	5	-	-	PUNCT
dti-2185	292	6	cruz	cruz	PROPN
dti-2185	292	7	g	g	PROPN
dti-2185	292	8	,	,	PUNCT
dti-2185	292	9	bonales	bonale	NOUN
dti-2185	292	10	-	-	PUNCT
dti-2185	292	11	alatorre	alatorre	NOUN
dti-2185	292	12	e	e	NOUN
dti-2185	292	13	,	,	PUNCT
dti-2185	292	14	shabala	shabala	PROPN
dti-2185	292	15	sn	sn	PROPN
dti-2185	292	16	,	,	PUNCT
dti-2185	292	17	dobrovinskaya	dobrovinskaya	NOUN
dti-2185	292	18	or	or	CCONJ
dti-2185	292	19	.	.	PUNCT
dti-2185	293	1	methyl	methyl	NOUN
dti-2185	293	2	-	-	PUNCT
dti-2185	293	3	β	β	NOUN
dti-2185	293	4	-	-	PUNCT
dti-2185	293	5	cyclodextrin	cyclodextrin	NOUN
dti-2185	293	6	reversibly	reversibly	ADV
dti-2185	293	7	alters	alter	VERB
dti-2185	293	8	the	the	DET
dti-2185	293	9	gating	gating	NOUN
dti-2185	293	10	of	of	ADP
dti-2185	293	11	lipid	lipid	ADJ
dti-2185	293	12	rafts	raft	NOUN
dti-2185	293	13	-	-	PUNCT
dti-2185	293	14	associated	associate	VERB
dti-2185	293	15	kv1.3	kv1.3	ADJ
dti-2185	293	16	channels	channel	NOUN
dti-2185	293	17	in	in	ADP
dti-2185	293	18	jurkat	jurkat	PROPN
dti-2185	293	19	t	t	PROPN
dti-2185	293	20	lymphocytes	lymphocytes	PROPN
dti-2185	293	21	.	.	PUNCT
dti-2185	294	1	pflugers	pfluger	NOUN
dti-2185	294	2	arch	arch	VERB
dti-2185	294	3	.	.	PUNCT
dti-2185	295	1	2007;454(2):235	2007;454(2):235	X
dti-2185	295	2	-	-	SYM
dti-2185	295	3	244	244	NUM
dti-2185	295	4	.	.	PUNCT
dti-2185	296	1	crossref	crossref	PROPN
dti-2185	296	2	medline	medline	PROPN
dti-2185	296	3	14	14	NUM
dti-2185	296	4	.	.	PUNCT
dti-2185	297	1	levitt	levitt	PROPN
dti-2185	297	2	es	es	PROPN
dti-2185	297	3	,	,	PUNCT
dti-2185	297	4	clark	clark	PROPN
dti-2185	297	5	mj	mj	PROPN
dti-2185	297	6	,	,	PUNCT
dti-2185	297	7	jenkins	jenkins	PROPN
dti-2185	297	8	pm	pm	PROPN
dti-2185	297	9	,	,	PUNCT
dti-2185	297	10	martens	martens	PROPN
dti-2185	297	11	jr	jr	PROPN
dti-2185	297	12	,	,	PUNCT
dti-2185	297	13	traynor	traynor	PROPN
dti-2185	297	14	jr	jr	PROPN
dti-2185	297	15	.	.	PROPN
dti-2185	297	16	differential	differential	ADJ
dti-2185	297	17	effect	effect	NOUN
dti-2185	297	18	of	of	ADP
dti-2185	297	19	membrane	membrane	ADJ
dti-2185	297	20	cholesterol	cholesterol	NOUN
dti-2185	297	21	removal	removal	NOUN
dti-2185	297	22	on	on	ADP
dti-2185	297	23	μand	μand	PROPN
dti-2185	297	24	δ	δ	PROPN
dti-2185	297	25	-	-	PUNCT
dti-2185	297	26	opioid	opioid	ADJ
dti-2185	297	27	receptors	receptor	NOUN
dti-2185	297	28	:	:	PUNCT
dti-2185	297	29	a	a	DET
dti-2185	297	30	parallel	parallel	ADJ
dti-2185	297	31	comparison	comparison	NOUN
dti-2185	297	32	of	of	ADP
dti-2185	297	33	acute	acute	ADJ
dti-2185	297	34	and	and	CCONJ
dti-2185	297	35	chronic	chronic	ADJ
dti-2185	297	36	signaling	signal	VERB
dti-2185	297	37	to	to	ADP
dti-2185	297	38	adenylyl	adenylyl	NOUN
dti-2185	297	39	cyclase	cyclase	NOUN
dti-2185	297	40	.	.	PUNCT
dti-2185	298	1	j	j	PROPN
dti-2185	298	2	biol	biol	PROPN
dti-2185	298	3	chem	chem	NOUN
dti-2185	298	4	.	.	PUNCT
dti-2185	299	1	2009;284(33):2210822122	2009;284(33):2210822122	NUM
dti-2185	299	2	.	.	PUNCT
dti-2185	300	1	crossref	crossref	PROPN
dti-2185	300	2	medline	medline	PROPN
dti-2185	300	3	15	15	NUM
dti-2185	300	4	.	.	PUNCT
dti-2185	301	1	ding	ding	PROPN
dti-2185	301	2	xq	xq	PROPN
dti-2185	301	3	,	,	PUNCT
dti-2185	301	4	fitzgerald	fitzgerald	PROPN
dti-2185	301	5	jb	jb	PROPN
dti-2185	301	6	,	,	PUNCT
dti-2185	301	7	matveev	matveev	PROPN
dti-2185	301	8	av	av	PROPN
dti-2185	301	9	,	,	PUNCT
dti-2185	301	10	mcclellan	mcclellan	PROPN
dti-2185	301	11	me	me	PROPN
dti-2185	301	12	,	,	PUNCT
dti-2185	301	13	elliott	elliott	PROPN
dti-2185	301	14	mh	mh	PROPN
dti-2185	301	15	.	.	PUNCT
dti-2185	302	1	functional	functional	ADJ
dti-2185	302	2	activity	activity	NOUN
dti-2185	302	3	of	of	ADP
dti-2185	302	4	photoreceptor	photoreceptor	NOUN
dti-2185	302	5	cyclic	cyclic	ADJ
dti-2185	302	6	nucleotide	nucleotide	NOUN
dti-2185	302	7	-	-	PUNCT
dti-2185	302	8	gated	gate	VERB
dti-2185	302	9	channels	channel	NOUN
dti-2185	302	10	is	be	AUX
dti-2185	302	11	dependent	dependent	ADJ
dti-2185	302	12	on	on	ADP
dti-2185	302	13	the	the	DET
dti-2185	302	14	integrity	integrity	NOUN
dti-2185	302	15	of	of	ADP
dti-2185	302	16	cholesteroland	cholesteroland	PROPN
dti-2185	302	17	sphingolipid	sphingolipid	PROPN
dti-2185	302	18	-	-	PUNCT
dti-2185	302	19	enriched	enrich	VERB
dti-2185	302	20	membrane	membrane	NOUN
dti-2185	302	21	domains	domain	NOUN
dti-2185	302	22	.	.	PUNCT
dti-2185	303	1	biochemistry	biochemistry	NOUN
dti-2185	303	2	.	.	PUNCT
dti-2185	304	1	2008;47(12):3677	2008;47(12):3677	NUM
dti-2185	304	2	-	-	SYM
dti-2185	304	3	3687	3687	NUM
dti-2185	304	4	.	.	PUNCT
dti-2185	305	1	crossref	crossref	PROPN
dti-2185	305	2	medline	medline	PROPN
dti-2185	305	3	16	16	NUM
dti-2185	305	4	.	.	PUNCT
dti-2185	306	1	gandhavadi	gandhavadi	PROPN
dti-2185	306	2	m	m	PROPN
dti-2185	306	3	,	,	PUNCT
dti-2185	306	4	allende	allende	PROPN
dti-2185	306	5	d	d	PROPN
dti-2185	306	6	,	,	PUNCT
dti-2185	306	7	vidal	vidal	PROPN
dti-2185	306	8	a	a	PROPN
dti-2185	306	9	,	,	PUNCT
dti-2185	306	10	simon	simon	PROPN
dti-2185	306	11	sa	sa	PROPN
dti-2185	306	12	,	,	PUNCT
dti-2185	306	13	mcintosh	mcintosh	PROPN
dti-2185	306	14	tj	tj	PROPN
dti-2185	306	15	.	.	PROPN
dti-2185	306	16	structure	structure	NOUN
dti-2185	306	17	,	,	PUNCT
dti-2185	306	18	composition	composition	NOUN
dti-2185	306	19	,	,	PUNCT
dti-2185	306	20	and	and	CCONJ
dti-2185	306	21	peptide	peptide	ADJ
dti-2185	306	22	binding	bind	VERB
dti-2185	306	23	properties	property	NOUN
dti-2185	306	24	of	of	ADP
dti-2185	306	25	detergent	detergent	ADJ
dti-2185	306	26	soluble	soluble	ADJ
dti-2185	306	27	bilayers	bilayer	NOUN
dti-2185	306	28	and	and	CCONJ
dti-2185	306	29	detergent	detergent	ADJ
dti-2185	306	30	resistant	resistant	ADJ
dti-2185	306	31	rafts	raft	NOUN
dti-2185	306	32	.	.	PUNCT
dti-2185	307	1	biophys	biophy	NOUN
dti-2185	307	2	j.	j.	PROPN
dti-2185	307	3	2002;82(3):1469	2002;82(3):1469	PROPN
dti-2185	307	4	-	-	PROPN
dti-2185	307	5	1482	1482	NUM
dti-2185	307	6	.	.	PUNCT
dti-2185	308	1	crossref	crossref	PROPN
dti-2185	308	2	medline	medline	PROPN
dti-2185	308	3	17	17	NUM
dti-2185	308	4	.	.	PUNCT
dti-2185	309	1	koumanov	koumanov	PROPN
dti-2185	309	2	ks	ks	PROPN
dti-2185	309	3	,	,	PUNCT
dti-2185	309	4	tessier	tessier	PROPN
dti-2185	309	5	c	c	PROPN
dti-2185	309	6	,	,	PUNCT
dti-2185	309	7	momchilova	momchilova	PROPN
dti-2185	309	8	ab	ab	PROPN
dti-2185	309	9	,	,	PUNCT
dti-2185	309	10	rainteau	rainteau	NOUN
dti-2185	309	11	d	d	NOUN
dti-2185	309	12	,	,	PUNCT
dti-2185	309	13	wolf	wolf	PROPN
dti-2185	309	14	c	c	AUX
dti-2185	309	15	,	,	PUNCT
dti-2185	309	16	quinn	quinn	PROPN
dti-2185	309	17	pj	pj	PROPN
dti-2185	309	18	.	.	PROPN
dti-2185	309	19	comparative	comparative	ADJ
dti-2185	309	20	lipid	lipid	NOUN
dti-2185	309	21	analysis	analysis	NOUN
dti-2185	309	22	and	and	CCONJ
dti-2185	309	23	structure	structure	NOUN
dti-2185	309	24	of	of	ADP
dti-2185	309	25	detergentresistant	detergentresistant	ADJ
dti-2185	309	26	membrane	membrane	NOUN
dti-2185	309	27	raft	raft	NOUN
dti-2185	309	28	fractions	fraction	NOUN
dti-2185	309	29	isolated	isolate	VERB
dti-2185	309	30	from	from	ADP
dti-2185	309	31	human	human	ADJ
dti-2185	309	32	and	and	CCONJ
dti-2185	309	33	ruminant	ruminant	NOUN
dti-2185	309	34	erythrocytes	erythrocyte	NOUN
dti-2185	309	35	.	.	PUNCT
dti-2185	310	1	arch	arch	ADJ
dti-2185	310	2	biochem	biochem	PROPN
dti-2185	310	3	biophys	biophy	NOUN
dti-2185	310	4	.	.	PUNCT
dti-2185	311	1	2005;434(1	2005;434(1	NUM
dti-2185	311	2	):	):	PUNCT
dti-2185	312	1	150	150	NUM
dti-2185	312	2	-	-	SYM
dti-2185	312	3	158	158	NUM
dti-2185	312	4	.	.	PUNCT
dti-2185	313	1	crossref	crossref	PROPN
dti-2185	313	2	medline	medline	PROPN
dti-2185	313	3	18	18	NUM
dti-2185	313	4	.	.	PUNCT
dti-2185	314	1	holland	holland	PROPN
dti-2185	314	2	gp	gp	PROPN
dti-2185	314	3	,	,	PUNCT
dti-2185	314	4	mcintyre	mcintyre	PROPN
dti-2185	314	5	sk	sk	PROPN
dti-2185	314	6	,	,	PUNCT
dti-2185	314	7	alam	alam	PROPN
dti-2185	314	8	tm	tm	PROPN
dti-2185	314	9	.	.	PUNCT
dti-2185	314	10	distinguishing	distinguish	VERB
dti-2185	314	11	individual	individual	ADJ
dti-2185	314	12	lipid	lipid	NOUN
dti-2185	314	13	headgroup	headgroup	NOUN
dti-2185	314	14	mobility	mobility	NOUN
dti-2185	314	15	and	and	CCONJ
dti-2185	314	16	phase	phase	NOUN
dti-2185	314	17	transitions	transition	NOUN
dti-2185	314	18	in	in	ADP
dti-2185	314	19	raft	raft	NOUN
dti-2185	314	20	-	-	PUNCT
dti-2185	314	21	forming	form	VERB
dti-2185	314	22	lipid	lipid	NOUN
dti-2185	314	23	mixtures	mixture	NOUN
dti-2185	314	24	with	with	ADP
dti-2185	314	25	31p	31p	ADJ
dti-2185	314	26	mas	mas	PROPN
dti-2185	314	27	nmr	nmr	NOUN
dti-2185	314	28	.	.	PUNCT
dti-2185	315	1	biophys	biophys	PROPN
dti-2185	315	2	j.	j.	PROPN
dti-2185	316	1	2006;90(11):42484260	2006;90(11):42484260	PROPN
dti-2185	316	2	.	.	PUNCT
dti-2185	316	3	crossref	crossref	PROPN
dti-2185	316	4	medline	medline	PROPN
dti-2185	316	5	19	19	NUM
dti-2185	316	6	.	.	PUNCT
dti-2185	317	1	simons	simons	PROPN
dti-2185	317	2	k	k	PROPN
dti-2185	317	3	,	,	PUNCT
dti-2185	317	4	ehehalt	ehehalt	PROPN
dti-2185	317	5	r.	r.	PROPN
dti-2185	317	6	cholesterol	cholesterol	PROPN
dti-2185	317	7	,	,	PUNCT
dti-2185	317	8	lipid	lipid	NOUN
dti-2185	317	9	rafts	raft	NOUN
dti-2185	317	10	,	,	PUNCT
dti-2185	317	11	and	and	CCONJ
dti-2185	317	12	disease	disease	NOUN
dti-2185	317	13	.	.	PUNCT
dti-2185	318	1	j	j	PROPN
dti-2185	318	2	clin	clin	PROPN
dti-2185	318	3	invest	invest	PROPN
dti-2185	318	4	.	.	PUNCT
dti-2185	319	1	2002;110(5):597	2002;110(5):597	NUM
dti-2185	319	2	-	-	SYM
dti-2185	319	3	603	603	NUM
dti-2185	319	4	.	.	PUNCT
dti-2185	319	5	crossref	crossref	PROPN
dti-2185	319	6	medline	medline	PROPN
dti-2185	319	7	20	20	NUM
dti-2185	319	8	.	.	PUNCT
dti-2185	320	1	jacobson	jacobson	PROPN
dti-2185	320	2	k	k	PROPN
dti-2185	320	3	,	,	PUNCT
dti-2185	320	4	mouritsen	mouritsen	VERB
dti-2185	320	5	og	og	PROPN
dti-2185	320	6	,	,	PUNCT
dti-2185	320	7	anderson	anderson	PROPN
dti-2185	320	8	rg	rg	PROPN
dti-2185	320	9	.	.	PROPN
dti-2185	320	10	lipid	lipid	PROPN
dti-2185	320	11	rafts	raft	NOUN
dti-2185	320	12	:	:	PUNCT
dti-2185	320	13	at	at	ADP
dti-2185	320	14	a	a	DET
dti-2185	320	15	crossroad	crossroad	NOUN
dti-2185	320	16	between	between	ADP
dti-2185	320	17	cell	cell	NOUN
dti-2185	320	18	biology	biology	NOUN
dti-2185	320	19	and	and	CCONJ
dti-2185	320	20	physics	physics	NOUN
dti-2185	320	21	.	.	PUNCT
dti-2185	321	1	nat	nat	PROPN
dti-2185	321	2	cell	cell	NOUN
dti-2185	321	3	biol	biol	PROPN
dti-2185	321	4	.	.	PUNCT
dti-2185	322	1	2007;9(1):7	2007;9(1):7	NUM
dti-2185	322	2	-	-	SYM
dti-2185	322	3	14	14	NUM
dti-2185	322	4	.	.	PUNCT
dti-2185	323	1	crossref	crossref	PROPN
dti-2185	323	2	medline	medline	PROPN
dti-2185	323	3	21	21	NUM
dti-2185	323	4	.	.	PUNCT
dti-2185	324	1	boesze	boesze	PROPN
dti-2185	324	2	-	-	PUNCT
dti-2185	324	3	battaglia	battaglia	PROPN
dti-2185	324	4	k.	k.	PROPN
dti-2185	324	5	isolation	isolation	NOUN
dti-2185	324	6	of	of	ADP
dti-2185	324	7	membrane	membrane	NOUN
dti-2185	324	8	rafts	raft	NOUN
dti-2185	324	9	and	and	CCONJ
dti-2185	324	10	signaling	signal	VERB
dti-2185	324	11	complexes	complex	NOUN
dti-2185	324	12	.	.	PUNCT
dti-2185	325	1	methods	method	NOUN
dti-2185	325	2	mol	mol	ADP
dti-2185	325	3	biol	biol	PROPN
dti-2185	325	4	.	.	PUNCT
dti-2185	326	1	2006;332:169	2006;332:169	NUM
dti-2185	326	2	-	-	SYM
dti-2185	326	3	179	179	NUM
dti-2185	326	4	.	.	PUNCT
dti-2185	327	1	crossref	crossref	PROPN
dti-2185	327	2	medline	medline	PROPN
dti-2185	327	3	22	22	NUM
dti-2185	327	4	.	.	PUNCT
dti-2185	328	1	loftsson	loftsson	PROPN
dti-2185	328	2	t	t	PROPN
dti-2185	328	3	,	,	PUNCT
dti-2185	328	4	magnúsdóttir	magnúsdóttir	VERB
dti-2185	328	5	a	a	DET
dti-2185	328	6	,	,	PUNCT
dti-2185	328	7	másson	másson	PROPN
dti-2185	328	8	m	m	PROPN
dti-2185	328	9	,	,	PUNCT
dti-2185	328	10	sigurjónsdóttir	sigurjónsdóttir	VERB
dti-2185	328	11	jf	jf	PROPN
dti-2185	328	12	.	.	PUNCT
dti-2185	329	1	selfassociation	selfassociation	PROPN
dti-2185	329	2	and	and	CCONJ
dti-2185	329	3	cyclodextrin	cyclodextrin	NOUN
dti-2185	329	4	solubilization	solubilization	NOUN
dti-2185	329	5	of	of	ADP
dti-2185	329	6	drugs	drug	NOUN
dti-2185	329	7	.	.	PUNCT
dti-2185	330	1	j	j	PROPN
dti-2185	330	2	pharm	pharm	PROPN
dti-2185	330	3	sci	sci	PROPN
dti-2185	330	4	.	.	PUNCT
dti-2185	331	1	2002;91(11):2307	2002;91(11):2307	NUM
dti-2185	331	2	-	-	SYM
dti-2185	331	3	2316	2316	NUM
dti-2185	331	4	.	.	PUNCT
dti-2185	332	1	crossref	crossref	PROPN
dti-2185	332	2	medline	medline	NOUN
dti-2185	332	3	23	23	NUM
dti-2185	332	4	.	.	PUNCT
dti-2185	333	1	mahammad	mahammad	PROPN
dti-2185	333	2	s	s	PROPN
dti-2185	333	3	,	,	PUNCT
dti-2185	333	4	parmryd	parmryd	PROPN
dti-2185	333	5	i.	i.	PROPN
dti-2185	333	6	cholesterol	cholesterol	PROPN
dti-2185	333	7	depletion	depletion	NOUN
dti-2185	333	8	using	use	VERB
dti-2185	333	9	methylβ	methylβ	NOUN
dti-2185	333	10	-	-	PUNCT
dti-2185	333	11	cyclodextrin	cyclodextrin	NOUN
dti-2185	333	12	.	.	PUNCT
dti-2185	334	1	methods	method	NOUN
dti-2185	334	2	mol	mol	ADP
dti-2185	334	3	biol	biol	PROPN
dti-2185	334	4	.	.	PUNCT
dti-2185	335	1	2015;1232:91	2015;1232:91	NUM
dti-2185	335	2	-	-	SYM
dti-2185	335	3	102	102	NUM
dti-2185	335	4	.	.	PUNCT
dti-2185	336	1	crossref	crossref	PROPN
dti-2185	336	2	medline	medline	NOUN
dti-2185	336	3	24	24	NUM
dti-2185	336	4	.	.	PUNCT
dti-2185	337	1	chau	chau	PROPN
dti-2185	337	2	pl	pl	PROPN
dti-2185	337	3	.	.	PUNCT
dti-2185	337	4	new	new	ADJ
dti-2185	337	5	insights	insight	NOUN
dti-2185	337	6	into	into	ADP
dti-2185	337	7	the	the	DET
dti-2185	337	8	molecular	molecular	ADJ
dti-2185	337	9	mechanisms	mechanism	NOUN
dti-2185	337	10	of	of	ADP
dti-2185	337	11	general	general	ADJ
dti-2185	337	12	anaesthetics	anaesthetic	NOUN
dti-2185	337	13	.	.	PUNCT
dti-2185	338	1	br	br	PROPN
dti-2185	338	2	j	j	PROPN
dti-2185	338	3	pharmacol	pharmacol	PROPN
dti-2185	338	4	.	.	PUNCT
dti-2185	339	1	2010;161(2):288	2010;161(2):288	NUM
dti-2185	339	2	-	-	SYM
dti-2185	339	3	307	307	NUM
dti-2185	339	4	.	.	PUNCT
dti-2185	340	1	crossref	crossref	PROPN
dti-2185	340	2	medline	medline	PROPN
dti-2185	340	3	25	25	NUM
dti-2185	340	4	.	.	PUNCT
dti-2185	341	1	olsen	olsen	PROPN
dti-2185	341	2	rw	rw	PROPN
dti-2185	341	3	,	,	PUNCT
dti-2185	341	4	li	li	PROPN
dti-2185	341	5	gd	gd	PROPN
dti-2185	341	6	.	.	PUNCT
dti-2185	341	7	gaba	gaba	PROPN
dti-2185	341	8	a	a	DET
dti-2185	341	9	receptors	receptor	NOUN
dti-2185	341	10	as	as	ADP
dti-2185	341	11	molecular	molecular	ADJ
dti-2185	341	12	targets	target	NOUN
dti-2185	341	13	of	of	ADP
dti-2185	341	14	general	general	ADJ
dti-2185	341	15	anesthetics	anesthetic	NOUN
dti-2185	341	16	:	:	PUNCT
dti-2185	341	17	identification	identification	NOUN
dti-2185	341	18	of	of	ADP
dti-2185	341	19	binding	bind	VERB
dti-2185	341	20	sites	site	NOUN
dti-2185	341	21	provides	provide	VERB
dti-2185	341	22	clues	clue	NOUN
dti-2185	341	23	to	to	ADP
dti-2185	341	24	allosteric	allosteric	ADJ
dti-2185	341	25	modulation	modulation	NOUN
dti-2185	341	26	.	.	PUNCT
dti-2185	342	1	can	can	AUX
dti-2185	342	2	j	j	PROPN
dti-2185	342	3	anaesth	anaesth	PROPN
dti-2185	342	4	.	.	PUNCT
dti-2185	343	1	2011;58(2):206	2011;58(2):206	NUM
dti-2185	343	2	-	-	PUNCT
dti-2185	343	3	215	215	NUM
dti-2185	343	4	.	.	PUNCT
dti-2185	343	5	crossref	crossref	PROPN
dti-2185	343	6	medline	medline	PROPN
dti-2185	343	7	26	26	NUM
dti-2185	343	8	.	.	PUNCT
dti-2185	344	1	yamakura	yamakura	PROPN
dti-2185	344	2	t	t	PROPN
dti-2185	344	3	,	,	PUNCT
dti-2185	344	4	harris	harris	PROPN
dti-2185	344	5	ra	ra	PROPN
dti-2185	344	6	.	.	PUNCT
dti-2185	345	1	effects	effect	NOUN
dti-2185	345	2	of	of	ADP
dti-2185	345	3	gaseous	gaseous	ADJ
dti-2185	345	4	anesthetics	anesthetic	NOUN
dti-2185	345	5	nitrous	nitrous	ADJ
dti-2185	345	6	oxide	oxide	NOUN
dti-2185	345	7	and	and	CCONJ
dti-2185	345	8	xenon	xenon	NOUN
dti-2185	345	9	on	on	ADP
dti-2185	345	10	ligand	ligand	NOUN
dti-2185	345	11	-	-	PUNCT
dti-2185	345	12	gated	gate	VERB
dti-2185	345	13	ion	ion	NOUN
dti-2185	345	14	channels	channel	NOUN
dti-2185	345	15	.	.	PUNCT
dti-2185	346	1	comparison	comparison	NOUN
dti-2185	346	2	with	with	ADP
dti-2185	346	3	isoflurane	isoflurane	NOUN
dti-2185	346	4	and	and	CCONJ
dti-2185	346	5	ethanol	ethanol	NOUN
dti-2185	346	6	.	.	PUNCT
dti-2185	347	1	anesthesiology	anesthesiology	NOUN
dti-2185	347	2	.	.	PUNCT
dti-2185	348	1	2000;93(4):10951101	2000;93(4):10951101	NUM
dti-2185	348	2	.	.	PUNCT
dti-2185	349	1	crossref	crossref	PROPN
dti-2185	349	2	medline	medline	PROPN
dti-2185	349	3	27	27	NUM
dti-2185	349	4	.	.	PUNCT
dti-2185	350	1	daniell	daniell	PROPN
dti-2185	350	2	lc	lc	PROPN
dti-2185	350	3	.	.	PROPN
dti-2185	350	4	effect	effect	NOUN
dti-2185	350	5	of	of	ADP
dti-2185	350	6	anesthetic	anesthetic	NOUN
dti-2185	350	7	and	and	CCONJ
dti-2185	350	8	convulsant	convulsant	NOUN
dti-2185	350	9	barbiturates	barbiturate	NOUN
dti-2185	350	10	on	on	ADP
dti-2185	350	11	n	n	CCONJ
dti-2185	350	12	-	-	PUNCT
dti-2185	350	13	methyl	methyl	NOUN
dti-2185	350	14	-	-	PUNCT
dti-2185	350	15	d	d	NOUN
dti-2185	350	16	-	-	PUNCT
dti-2185	350	17	aspartate	aspartate	ADJ
dti-2185	350	18	receptor	receptor	NOUN
dti-2185	350	19	-	-	PUNCT
dti-2185	350	20	mediated	mediate	VERB
dti-2185	350	21	calcium	calcium	NOUN
dti-2185	350	22	flux	flux	NOUN
dti-2185	350	23	in	in	ADP
dti-2185	350	24	brain	brain	NOUN
dti-2185	350	25	membrane	membrane	NOUN
dti-2185	350	26	vesicles	vesicle	NOUN
dti-2185	350	27	.	.	PUNCT
dti-2185	351	1	pharmacology	pharmacology	NOUN
dti-2185	351	2	.	.	PUNCT
dti-2185	352	1	1994;49(5):296	1994;49(5):296	NUM
dti-2185	352	2	-	-	PUNCT
dti-2185	352	3	307	307	NUM
dti-2185	352	4	.	.	PUNCT
dti-2185	353	1	crossref	crossref	PROPN
dti-2185	353	2	medline	medline	PROPN
dti-2185	353	3	28	28	NUM
dti-2185	353	4	.	.	PUNCT
dti-2185	354	1	li	li	PROPN
dti-2185	354	2	x	x	PROPN
dti-2185	354	3	,	,	PUNCT
dti-2185	354	4	serwanski	serwanski	PROPN
dti-2185	354	5	dr	dr	PROPN
dti-2185	354	6	,	,	PUNCT
dti-2185	354	7	miralles	miralle	NOUN
dti-2185	354	8	cp	cp	PROPN
dti-2185	354	9	,	,	PUNCT
dti-2185	354	10	bahr	bahr	PROPN
dti-2185	354	11	ba	ba	PROPN
dti-2185	354	12	,	,	PUNCT
dti-2185	354	13	de	de	PROPN
dti-2185	354	14	blas	blas	PROPN
dti-2185	354	15	al	al	PROPN
dti-2185	354	16	.	.	PROPN
dti-2185	354	17	two	two	NUM
dti-2185	354	18	pools	pool	NOUN
dti-2185	354	19	of	of	ADP
dti-2185	354	20	triton	triton	PROPN
dti-2185	354	21	x-100	x-100	PROPN
dti-2185	354	22	-	-	PUNCT
dti-2185	354	23	insoluble	insoluble	ADJ
dti-2185	354	24	gabaa	gabaa	NOUN
dti-2185	354	25	receptors	receptor	NOUN
dti-2185	354	26	are	be	AUX
dti-2185	354	27	present	present	ADJ
dti-2185	354	28	in	in	ADP
dti-2185	354	29	the	the	DET
dti-2185	354	30	brain	brain	NOUN
dti-2185	354	31	,	,	PUNCT
dti-2185	354	32	one	one	NUM
dti-2185	354	33	associated	associate	VERB
dti-2185	354	34	to	to	ADP
dti-2185	354	35	lipid	lipid	NOUN
dti-2185	354	36	rafts	raft	NOUN
dti-2185	354	37	and	and	CCONJ
dti-2185	354	38	another	another	DET
dti-2185	354	39	one	one	NOUN
dti-2185	354	40	to	to	ADP
dti-2185	354	41	the	the	DET
dti-2185	354	42	postsynaptic	postsynaptic	ADJ
dti-2185	354	43	gabaergic	gabaergic	ADJ
dti-2185	354	44	complex	complex	NOUN
dti-2185	354	45	.	.	PUNCT
dti-2185	355	1	j	j	PROPN
dti-2185	355	2	neurochem	neurochem	PROPN
dti-2185	355	3	.	.	PUNCT
dti-2185	356	1	2007;102(4):13291345	2007;102(4):13291345	NUM
dti-2185	356	2	.	.	PUNCT
dti-2185	356	3	crossref	crossref	PROPN
dti-2185	356	4	medline	medline	PROPN
dti-2185	356	5	29	29	NUM
dti-2185	356	6	.	.	PUNCT
dti-2185	357	1	parat	parat	PROPN
dti-2185	357	2	mo	mo	PROPN
dti-2185	357	3	.	.	PROPN
dti-2185	357	4	could	could	AUX
dti-2185	357	5	endothelial	endothelial	NOUN
dti-2185	357	6	caveolae	caveolae	NOUN
dti-2185	357	7	be	be	AUX
dti-2185	357	8	the	the	DET
dti-2185	357	9	target	target	NOUN
dti-2185	357	10	of	of	ADP
dti-2185	357	11	general	general	ADJ
dti-2185	357	12	anaesthetics	anaesthetic	NOUN
dti-2185	357	13	?	?	PUNCT
dti-2185	358	1	br	br	PROPN
dti-2185	358	2	j	j	PROPN
dti-2185	358	3	anaesth	anaesth	PROPN
dti-2185	358	4	.	.	PUNCT
dti-2185	359	1	2006;96(5):547	2006;96(5):547	PROPN
dti-2185	359	2	-	-	PUNCT
dti-2185	359	3	550	550	NUM
dti-2185	359	4	.	.	PUNCT
dti-2185	360	1	crossref	crossref	PROPN
dti-2185	360	2	medline	medline	PROPN
dti-2185	360	3	30	30	NUM
dti-2185	360	4	.	.	PUNCT
dti-2185	361	1	tsuchiya	tsuchiya	PROPN
dti-2185	361	2	h.	h.	PROPN
dti-2185	361	3	structure	structure	NOUN
dti-2185	361	4	-	-	PUNCT
dti-2185	361	5	specific	specific	ADJ
dti-2185	361	6	membrane	membrane	NOUN
dti-2185	361	7	-	-	PUNCT
dti-2185	361	8	fluidizing	fluidize	VERB
dti-2185	361	9	effect	effect	NOUN
dti-2185	361	10	of	of	ADP
dti-2185	361	11	propofol	propofol	NOUN
dti-2185	361	12	.	.	PUNCT
dti-2185	362	1	clin	clin	PROPN
dti-2185	362	2	exp	exp	PROPN
dti-2185	362	3	pharmacol	pharmacol	PROPN
dti-2185	362	4	physiol	physiol	PROPN
dti-2185	362	5	.	.	PUNCT
dti-2185	363	1	2001;28(4):292	2001;28(4):292	NUM
dti-2185	363	2	-	-	SYM
dti-2185	363	3	299	299	NUM
dti-2185	363	4	.	.	PUNCT
dti-2185	363	5	crossref	crossref	PROPN
dti-2185	363	6	medline	medline	NOUN
dti-2185	363	7	31	31	NUM
dti-2185	363	8	.	.	PUNCT
dti-2185	364	1	tsuchiya	tsuchiya	PROPN
dti-2185	364	2	h	h	PROPN
dti-2185	364	3	,	,	PUNCT
dti-2185	364	4	ueno	ueno	PROPN
dti-2185	364	5	t	t	PROPN
dti-2185	364	6	,	,	PUNCT
dti-2185	364	7	tanaka	tanaka	PROPN
dti-2185	364	8	t	t	PROPN
dti-2185	364	9	,	,	PUNCT
dti-2185	364	10	matsuura	matsuura	PROPN
dti-2185	364	11	n	n	PROPN
dti-2185	364	12	,	,	PUNCT
dti-2185	364	13	mizogami	mizogami	PROPN
dti-2185	364	14	m.	m.	PROPN
dti-2185	364	15	comparative	comparative	ADJ
dti-2185	364	16	study	study	NOUN
dti-2185	364	17	on	on	ADP
dti-2185	364	18	determination	determination	NOUN
dti-2185	364	19	of	of	ADP
dti-2185	364	20	antioxidant	antioxidant	ADJ
dti-2185	364	21	and	and	CCONJ
dti-2185	364	22	membrane	membrane	NOUN
dti-2185	364	23	activities	activity	NOUN
dti-2185	364	24	of	of	ADP
dti-2185	364	25	propofol	propofol	NOUN
dti-2185	364	26	and	and	CCONJ
dti-2185	364	27	its	its	PRON
dti-2185	364	28	related	related	ADJ
dti-2185	364	29	compounds	compound	NOUN
dti-2185	364	30	.	.	PUNCT
dti-2185	365	1	eur	eur	PROPN
dti-2185	365	2	j	j	PROPN
dti-2185	365	3	pharm	pharm	PROPN
dti-2185	365	4	sci	sci	PROPN
dti-2185	365	5	.	.	PUNCT
dti-2185	366	1	2010;39(1	2010;39(1	NUM
dti-2185	366	2	-	-	PUNCT
dti-2185	366	3	3):97	3):97	NUM
dti-2185	366	4	-	-	PUNCT
dti-2185	366	5	102	102	NUM
dti-2185	366	6	.	.	PUNCT
dti-2185	367	1	crossref	crossref	PROPN
dti-2185	367	2	medline	medline	NOUN
dti-2185	367	3	32	32	NUM
dti-2185	367	4	.	.	PUNCT
dti-2185	368	1	gray	gray	ADJ
dti-2185	368	2	e	e	NOUN
dti-2185	368	3	,	,	PUNCT
dti-2185	368	4	karslake	karslake	PROPN
dti-2185	368	5	j	j	PROPN
dti-2185	368	6	,	,	PUNCT
dti-2185	368	7	machta	machta	PROPN
dti-2185	368	8	bb	bb	PROPN
dti-2185	368	9	,	,	PUNCT
dti-2185	368	10	veatch	veatch	NOUN
dti-2185	368	11	sl	sl	NOUN
dti-2185	368	12	.	.	PUNCT
dti-2185	369	1	liquid	liquid	ADJ
dti-2185	369	2	general	general	ADJ
dti-2185	369	3	anesthetics	anesthetic	NOUN
dti-2185	369	4	lower	low	ADJ
dti-2185	369	5	critical	critical	ADJ
dti-2185	369	6	temperatures	temperature	NOUN
dti-2185	369	7	in	in	ADP
dti-2185	369	8	plasma	plasma	NOUN
dti-2185	369	9	membrane	membrane	NOUN
dti-2185	369	10	vesicles	vesicle	NOUN
dti-2185	369	11	.	.	PUNCT
dti-2185	370	1	biophys	biophy	NOUN
dti-2185	370	2	j.	j.	PROPN
dti-2185	370	3	2013;105(12):2751	2013;105(12):2751	PROPN
dti-2185	370	4	-	-	PUNCT
dti-2185	370	5	2759	2759	NUM
dti-2185	370	6	.	.	PUNCT
dti-2185	371	1	crossref	crossref	PROPN
dti-2185	371	2	medline	medline	PROPN
dti-2185	371	3	33	33	NUM
dti-2185	371	4	.	.	PUNCT
dti-2185	372	1	grim	grim	PROPN
dti-2185	372	2	kj	kj	PROPN
dti-2185	372	3	,	,	PUNCT
dti-2185	372	4	abcejo	abcejo	PROPN
dti-2185	372	5	aj	aj	PROPN
dti-2185	372	6	,	,	PUNCT
dti-2185	372	7	barnes	barnes	PROPN
dti-2185	372	8	a	a	PROPN
dti-2185	372	9	,	,	PUNCT
dti-2185	372	10	et	et	PROPN
dti-2185	372	11	al	al	PROPN
dti-2185	372	12	.	.	PUNCT
dti-2185	372	13	caveolae	caveolae	NOUN
dti-2185	372	14	and	and	CCONJ
dti-2185	372	15	propofol	propofol	NOUN
dti-2185	372	16	effects	effect	NOUN
dti-2185	372	17	on	on	ADP
dti-2185	372	18	airway	airway	NOUN
dti-2185	372	19	smooth	smooth	ADJ
dti-2185	372	20	muscle	muscle	NOUN
dti-2185	372	21	.	.	PUNCT
dti-2185	373	1	br	br	PROPN
dti-2185	373	2	j	j	PROPN
dti-2185	373	3	anaesth	anaesth	PROPN
dti-2185	373	4	.	.	PUNCT
dti-2185	374	1	2012;109(3):444453	2012;109(3):444453	NUM
dti-2185	374	2	.	.	PUNCT
dti-2185	374	3	crossref	crossref	PROPN
dti-2185	374	4	medline	medline	NOUN
dti-2185	374	5	34	34	NUM
dti-2185	374	6	.	.	PUNCT
dti-2185	375	1	patel	patel	PROPN
dti-2185	375	2	j	j	PROPN
dti-2185	375	3	,	,	PUNCT
dti-2185	375	4	chowdhury	chowdhury	PROPN
dti-2185	375	5	ea	ea	PROPN
dti-2185	375	6	,	,	PUNCT
dti-2185	375	7	noorani	noorani	PROPN
dti-2185	375	8	b	b	PROPN
dti-2185	375	9	,	,	PUNCT
dti-2185	375	10	bickel	bickel	PROPN
dti-2185	375	11	u	u	PROPN
dti-2185	375	12	,	,	PUNCT
dti-2185	375	13	huang	huang	PROPN
dti-2185	375	14	j.	j.	PROPN
dti-2185	375	15	isoflurane	isoflurane	PROPN
dti-2185	375	16	increases	increase	VERB
dti-2185	375	17	cell	cell	NOUN
dti-2185	375	18	membrane	membrane	NOUN
dti-2185	375	19	fluidity	fluidity	NOUN
dti-2185	375	20	significantly	significantly	ADV
dti-2185	375	21	at	at	ADP
dti-2185	375	22	clinical	clinical	ADJ
dti-2185	375	23	concentrations	concentration	NOUN
dti-2185	375	24	.	.	PUNCT
dti-2185	376	1	biochim	biochim	PROPN
dti-2185	376	2	biophys	biophy	NOUN
dti-2185	376	3	acta	acta	PROPN
dti-2185	376	4	biomembr	biomembr	NOUN
dti-2185	376	5	.	.	PUNCT
dti-2185	377	1	2020;1862(2):183140	2020;1862(2):183140	NUM
dti-2185	377	2	.	.	PUNCT
dti-2185	378	1	crossref	crossref	PROPN
dti-2185	378	2	medline	medline	PROPN
dti-2185	378	3	35	35	NUM
dti-2185	378	4	.	.	PUNCT
dti-2185	379	1	turkyilmaz	turkyilmaz	PROPN
dti-2185	379	2	s	s	PROPN
dti-2185	379	3	,	,	PUNCT
dti-2185	379	4	almeida	almeida	PROPN
dti-2185	379	5	pf	pf	PROPN
dti-2185	379	6	,	,	PUNCT
dti-2185	379	7	regen	regen	PROPN
dti-2185	379	8	sl	sl	PROPN
dti-2185	379	9	.	.	PUNCT
dti-2185	379	10	effects	effect	NOUN
dti-2185	379	11	of	of	ADP
dti-2185	379	12	isoflurane	isoflurane	NOUN
dti-2185	379	13	,	,	PUNCT
dti-2185	379	14	halothane	halothane	ADJ
dti-2185	379	15	,	,	PUNCT
dti-2185	379	16	and	and	CCONJ
dti-2185	379	17	chloroform	chloroform	NOUN
dti-2185	379	18	on	on	ADP
dti-2185	379	19	the	the	DET
dti-2185	379	20	interactions	interaction	NOUN
dti-2185	379	21	and	and	CCONJ
dti-2185	379	22	lateral	lateral	ADJ
dti-2185	379	23	organization	organization	NOUN
dti-2185	379	24	of	of	ADP
dti-2185	379	25	lipids	lipid	NOUN
dti-2185	379	26	in	in	ADP
dti-2185	379	27	the	the	DET
dti-2185	379	28	liquid	liquid	NOUN
dti-2185	379	29	-	-	PUNCT
dti-2185	379	30	ordered	order	VERB
dti-2185	379	31	phase	phase	NOUN
dti-2185	379	32	.	.	PUNCT
dti-2185	380	1	langmuir	langmuir	PROPN
dti-2185	380	2	.	.	PUNCT
dti-2185	381	1	2011;27(23):14380	2011;27(23):14380	X
dti-2185	381	2	-	-	SYM
dti-2185	381	3	14385	14385	NUM
dti-2185	381	4	.	.	PUNCT
dti-2185	382	1	crossref	crossref	PROPN
dti-2185	382	2	medline	medline	PROPN
dti-2185	382	3	36	36	NUM
dti-2185	382	4	.	.	PUNCT
dti-2185	383	1	weinrich	weinrich	PROPN
dti-2185	383	2	m	m	PROPN
dti-2185	383	3	,	,	PUNCT
dti-2185	383	4	nanda	nanda	ADJ
dti-2185	383	5	h	h	PROPN
dti-2185	383	6	,	,	PUNCT
dti-2185	383	7	worcester	worcester	PROPN
dti-2185	383	8	dl	dl	PROPN
dti-2185	383	9	,	,	PUNCT
dti-2185	383	10	majkrzak	majkrzak	NOUN
dti-2185	383	11	cf	cf	NOUN
dti-2185	383	12	,	,	PUNCT
dti-2185	383	13	maranville	maranville	NOUN
dti-2185	383	14	bb	bb	PROPN
dti-2185	383	15	,	,	PUNCT
dti-2185	383	16	bezrukov	bezrukov	PROPN
dti-2185	383	17	sm	sm	PROPN
dti-2185	383	18	.	.	PROPN
dti-2185	383	19	halothane	halothane	PROPN
dti-2185	383	20	changes	change	VERB
dti-2185	383	21	the	the	DET
dti-2185	383	22	domain	domain	NOUN
dti-2185	383	23	structure	structure	NOUN
dti-2185	383	24	of	of	ADP
dti-2185	383	25	a	a	DET
dti-2185	383	26	binary	binary	ADJ
dti-2185	383	27	lipid	lipid	NOUN
dti-2185	383	28	membrane	membrane	NOUN
dti-2185	383	29	.	.	PUNCT
dti-2185	384	1	langmuir	langmuir	PROPN
dti-2185	384	2	.	.	PUNCT
dti-2185	385	1	2012;28(10):4723	2012;28(10):4723	NUM
dti-2185	385	2	-	-	SYM
dti-2185	385	3	4728	4728	NUM
dti-2185	385	4	.	.	PUNCT
dti-2185	386	1	crossref	crossref	PROPN
dti-2185	386	2	medline	medline	PROPN
dti-2185	387	1	37	37	NUM
dti-2185	387	2	.	.	PUNCT
dti-2185	388	1	weinrich	weinrich	PROPN
dti-2185	388	2	m	m	PROPN
dti-2185	388	3	,	,	PUNCT
dti-2185	388	4	worcester	worcester	PROPN
dti-2185	388	5	dl	dl	PROPN
dti-2185	388	6	.	.	PROPN
dti-2185	388	7	xenon	xenon	PROPN
dti-2185	388	8	and	and	CCONJ
dti-2185	388	9	other	other	ADJ
dti-2185	388	10	volatile	volatile	ADJ
dti-2185	388	11	anesthetics	anesthetic	NOUN
dti-2185	388	12	change	change	VERB
dti-2185	388	13	domain	domain	NOUN
dti-2185	388	14	structure	structure	NOUN
dti-2185	388	15	in	in	ADP
dti-2185	388	16	model	model	NOUN
dti-2185	388	17	lipid	lipid	NOUN
dti-2185	388	18	raft	raft	NOUN
dti-2185	388	19	membranes	membrane	NOUN
dti-2185	388	20	.	.	PUNCT
dti-2185	389	1	j	j	PROPN
dti-2185	389	2	phys	phys	PROPN
dti-2185	389	3	chem	chem	PROPN
dti-2185	389	4	b.	b.	PROPN
dti-2185	389	5	2013;117(50):16141	2013;117(50):16141	PROPN
dti-2185	389	6	-	-	NUM
dti-2185	389	7	16147	16147	NUM
dti-2185	389	8	.	.	PUNCT
dti-2185	390	1	crossref	crossref	PROPN
dti-2185	390	2	medline	medline	NOUN
dti-2185	390	3	38	38	NUM
dti-2185	390	4	.	.	PUNCT
dti-2185	391	1	sierra	sierra	PROPN
dti-2185	391	2	-	-	PUNCT
dti-2185	391	3	valdez	valdez	PROPN
dti-2185	391	4	fj	fj	PROPN
dti-2185	391	5	,	,	PUNCT
dti-2185	391	6	ruiz	ruiz	NOUN
dti-2185	391	7	-	-	PUNCT
dti-2185	391	8	suárez	suárez	NOUN
dti-2185	391	9	jc	jc	PROPN
dti-2185	391	10	,	,	PUNCT
dti-2185	391	11	delint	delint	NOUN
dti-2185	391	12	-	-	PUNCT
dti-2185	391	13	ramirez	ramirez	PROPN
dti-2185	391	14	i.	i.	PROPN
dti-2185	391	15	pentobarbital	pentobarbital	PROPN
dti-2185	391	16	modifies	modify	VERB
dti-2185	391	17	the	the	DET
dti-2185	391	18	lipid	lipid	NOUN
dti-2185	391	19	raft	raft	NOUN
dti-2185	391	20	-	-	PUNCT
dti-2185	391	21	protein	protein	NOUN
dti-2185	391	22	interaction	interaction	NOUN
dti-2185	391	23	:	:	PUNCT
dti-2185	391	24	a	a	DET
dti-2185	391	25	first	first	ADJ
dti-2185	391	26	clue	clue	NOUN
dti-2185	391	27	about	about	ADP
dti-2185	391	28	the	the	DET
dti-2185	391	29	anesthesia	anesthesia	NOUN
dti-2185	391	30	mechanism	mechanism	NOUN
dti-2185	391	31	on	on	ADP
dti-2185	391	32	nmda	nmda	NOUN
dti-2185	391	33	and	and	CCONJ
dti-2185	391	34	gaba	gaba	VERB
dti-2185	391	35	a	a	DET
dti-2185	391	36	receptors	receptor	NOUN
dti-2185	391	37	.	.	PUNCT
dti-2185	392	1	biochim	biochim	PROPN
dti-2185	392	2	biophys	biophy	NOUN
dti-2185	392	3	acta	acta	PROPN
dti-2185	392	4	.	.	PUNCT
dti-2185	393	1	2016;1858(11):2603	2016;1858(11):2603	PROPN
dti-2185	393	2	-	-	SYM
dti-2185	393	3	2610	2610	NUM
dti-2185	393	4	.	.	PUNCT
dti-2185	394	1	crossref	crossref	PROPN
dti-2185	394	2	medline	medline	NOUN
dti-2185	394	3	39	39	NUM
dti-2185	394	4	.	.	PUNCT
dti-2185	395	1	fozzard	fozzard	PROPN
dti-2185	395	2	ha	ha	INTJ
dti-2185	395	3	,	,	PUNCT
dti-2185	395	4	lee	lee	PROPN
dti-2185	395	5	pj	pj	PROPN
dti-2185	395	6	,	,	PUNCT
dti-2185	395	7	lipkind	lipkind	ADJ
dti-2185	395	8	gm	gm	PROPN
dti-2185	395	9	.	.	PUNCT
dti-2185	396	1	mechanism	mechanism	NOUN
dti-2185	396	2	of	of	ADP
dti-2185	396	3	local	local	ADJ
dti-2185	396	4	anesthetic	anesthetic	ADJ
dti-2185	396	5	drug	drug	NOUN
dti-2185	396	6	action	action	NOUN
dti-2185	396	7	on	on	ADP
dti-2185	396	8	voltage	voltage	NOUN
dti-2185	396	9	-	-	PUNCT
dti-2185	396	10	gated	gate	VERB
dti-2185	396	11	sodium	sodium	NOUN
dti-2185	396	12	channels	channel	NOUN
dti-2185	396	13	.	.	PUNCT
dti-2185	397	1	curr	curr	PROPN
dti-2185	397	2	pharm	pharm	PROPN
dti-2185	397	3	des	des	PROPN
dti-2185	397	4	.	.	PROPN
dti-2185	397	5	2005;11(21):2671	2005;11(21):2671	NUM
dti-2185	397	6	-	-	SYM
dti-2185	397	7	2686	2686	NUM
dti-2185	397	8	.	.	PUNCT
dti-2185	398	1	crossref	crossref	PROPN
dti-2185	398	2	medline	medline	NOUN
dti-2185	398	3	40	40	NUM
dti-2185	398	4	.	.	PUNCT
dti-2185	399	1	pristerá	pristerá	PROPN
dti-2185	399	2	a	a	PRON
dti-2185	399	3	,	,	PUNCT
dti-2185	399	4	okuse	okuse	NOUN
dti-2185	399	5	k.	k.	PROPN
dti-2185	399	6	building	build	VERB
dti-2185	399	7	excitable	excitable	ADJ
dti-2185	399	8	membranes	membrane	NOUN
dti-2185	399	9	:	:	PUNCT
dti-2185	399	10	lipid	lipid	NOUN
dti-2185	399	11	rafts	raft	NOUN
dti-2185	399	12	and	and	CCONJ
dti-2185	399	13	multiple	multiple	ADJ
dti-2185	399	14	controls	control	NOUN
dti-2185	399	15	on	on	ADP
dti-2185	399	16	trafficking	trafficking	NOUN
dti-2185	399	17	of	of	ADP
dti-2185	399	18	electrogenic	electrogenic	ADJ
dti-2185	399	19	molecules	molecule	NOUN
dti-2185	399	20	.	.	PUNCT
dti-2185	400	1	neuroscientist	neuroscientist	NOUN
dti-2185	400	2	.	.	PUNCT
dti-2185	401	1	2012;18(1):70	2012;18(1):70	PROPN
dti-2185	401	2	-	-	SYM
dti-2185	401	3	81	81	NUM
dti-2185	401	4	.	.	PUNCT
dti-2185	402	1	crossref	crossref	PROPN
dti-2185	402	2	medline	medline	PROPN
dti-2185	402	3	41	41	NUM
dti-2185	402	4	.	.	PUNCT
dti-2185	403	1	bao	bao	PROPN
dti-2185	403	2	l.	l.	PROPN
dti-2185	403	3	trafficking	trafficking	NOUN
dti-2185	403	4	regulates	regulate	VERB
dti-2185	403	5	the	the	DET
dti-2185	403	6	subcellular	subcellular	ADJ
dti-2185	403	7	distribution	distribution	NOUN
dti-2185	403	8	of	of	ADP
dti-2185	403	9	voltage	voltage	NOUN
dti-2185	403	10	-	-	PUNCT
dti-2185	403	11	gated	gate	VERB
dti-2185	403	12	sodium	sodium	NOUN
dti-2185	403	13	channels	channel	NOUN
dti-2185	403	14	in	in	ADP
dti-2185	403	15	primary	primary	ADJ
dti-2185	403	16	sensory	sensory	ADJ
dti-2185	403	17	neurons	neuron	NOUN
dti-2185	403	18	.	.	PUNCT
dti-2185	404	1	mol	mol	ADP
dti-2185	404	2	pain	pain	NOUN
dti-2185	404	3	.	.	PUNCT
dti-2185	405	1	2015;11:61	2015;11:61	NUM
dti-2185	405	2	.	.	PUNCT
dti-2185	405	3	crossref	crossref	PROPN
dti-2185	405	4	medline	medline	NOUN
dti-2185	405	5	42	42	NUM
dti-2185	405	6	.	.	PUNCT
dti-2185	406	1	pristerà	pristerà	PROPN
dti-2185	406	2	a	a	PRON
dti-2185	406	3	,	,	PUNCT
dti-2185	406	4	baker	baker	PROPN
dti-2185	406	5	md	md	PROPN
dti-2185	406	6	,	,	PUNCT
dti-2185	406	7	okuse	okuse	PROPN
dti-2185	406	8	k.	k.	PROPN
dti-2185	406	9	association	association	PROPN
dti-2185	406	10	between	between	ADP
dti-2185	406	11	tetrodotoxin	tetrodotoxin	NOUN
dti-2185	406	12	resistant	resistant	ADJ
dti-2185	406	13	channels	channel	NOUN
dti-2185	406	14	and	and	CCONJ
dti-2185	406	15	lipid	lipid	NOUN
dti-2185	406	16	rafts	raft	NOUN
dti-2185	406	17	regulates	regulate	VERB
dti-2185	406	18	sensory	sensory	ADJ
dti-2185	406	19	neuron	neuron	NOUN
dti-2185	406	20	excitability	excitability	NOUN
dti-2185	406	21	.	.	PUNCT
dti-2185	407	1	plos	plos	PROPN
dti-2185	407	2	one	one	NUM
dti-2185	407	3	.	.	PUNCT
dti-2185	408	1	2012;7(8):e40079	2012;7(8):e40079	PROPN
dti-2185	408	2	.	.	PUNCT
dti-2185	408	3	crossref	crossref	PROPN
dti-2185	408	4	medline	medline	NOUN
dti-2185	408	5	43	43	NUM
dti-2185	408	6	.	.	PUNCT
dti-2185	409	1	kamata	kamata	PROPN
dti-2185	409	2	k	k	PROPN
dti-2185	409	3	,	,	PUNCT
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dti-2185	409	6	,	,	PUNCT
dti-2185	409	7	ozaki	ozaki	PROPN
dti-2185	409	8	m	m	PROPN
dti-2185	409	9	,	,	PUNCT
dti-2185	409	10	takakuwa	takakuwa	PROPN
dti-2185	409	11	y.	y.	PROPN
dti-2185	409	12	functional	functional	ADJ
dti-2185	409	13	evidence	evidence	NOUN
dti-2185	409	14	for	for	ADP
dti-2185	409	15	presence	presence	NOUN
dti-2185	409	16	of	of	ADP
dti-2185	409	17	lipid	lipid	ADJ
dti-2185	409	18	rafts	raft	NOUN
dti-2185	409	19	in	in	ADP
dti-2185	409	20	erythrocyte	erythrocyte	ADJ
dti-2185	409	21	membranes	membrane	NOUN
dti-2185	409	22	:	:	PUNCT
dti-2185	409	23	gsα	gsα	NOUN
dti-2185	409	24	in	in	ADP
dti-2185	409	25	rafts	raft	NOUN
dti-2185	409	26	is	be	AUX
dti-2185	409	27	essential	essential	ADJ
dti-2185	409	28	for	for	ADP
dti-2185	409	29	signal	signal	ADJ
dti-2185	409	30	transduction	transduction	NOUN
dti-2185	409	31	.	.	PUNCT
dti-2185	410	1	am	be	AUX
dti-2185	410	2	j	j	PROPN
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dti-2185	410	4	.	.	PUNCT
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dti-2185	411	2	-	-	SYM
dti-2185	411	3	375	375	NUM
dti-2185	411	4	.	.	PUNCT
dti-2185	412	1	crossref	crossref	PROPN
dti-2185	412	2	medline	medline	NOUN
dti-2185	412	3	44	44	NUM
dti-2185	412	4	.	.	PUNCT
dti-2185	413	1	bandeiras	bandeiras	PROPN
dti-2185	413	2	c	c	PROPN
dti-2185	413	3	,	,	PUNCT
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dti-2185	413	5	ap	ap	PROPN
dti-2185	413	6	,	,	PUNCT
dti-2185	413	7	luzyanin	luzyanin	PROPN
dti-2185	413	8	k	k	PROPN
dti-2185	413	9	,	,	PUNCT
dti-2185	413	10	fernandes	fernandes	PROPN
dti-2185	413	11	a	a	PROPN
dti-2185	413	12	,	,	PUNCT
dti-2185	413	13	saramago	saramago	PROPN
dti-2185	413	14	b.	b.	PROPN
dti-2185	413	15	anesthetics	anesthetic	NOUN
dti-2185	413	16	interacting	interact	VERB
dti-2185	413	17	with	with	ADP
dti-2185	413	18	lipid	lipid	ADJ
dti-2185	413	19	rafts	raft	NOUN
dti-2185	413	20	.	.	PUNCT
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dti-2185	414	2	j	j	PROPN
dti-2185	414	3	pharm	pharm	PROPN
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dti-2185	414	5	.	.	PUNCT
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dti-2185	415	2	-	-	PUNCT
dti-2185	415	3	2):153	2):153	NUM
dti-2185	415	4	-	-	PUNCT
dti-2185	415	5	165	165	NUM
dti-2185	415	6	.	.	PUNCT
dti-2185	415	7	crossref	crossref	PROPN
dti-2185	415	8	medline	medline	NOUN
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dti-2185	416	1	https://www.ncbi.nlm.nih.gov/pubmed/16405931	https://www.ncbi.nlm.nih.gov/pubmed/16405931	PRON
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dti-2185	416	4	https://doi.org/10.1007/978-3-540-72843-6_7	https://doi.org/10.1007/978-3-540-72843-6_7	NOUN
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dti-2185	416	6	https://doi.org/10.1074/jbc.m201644200	https://doi.org/10.1074/jbc.m201644200	PROPN
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dti-2185	418	3	https://doi.org/10.1172/jci0216390	https://doi.org/10.1172/jci0216390	X
dti-2185	418	4	https://www.ncbi.nlm.nih.gov/pubmed/12208858	https://www.ncbi.nlm.nih.gov/pubmed/12208858	NUM
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dti-2185	418	16	https://www.ncbi.nlm.nih.gov/pubmed/21194017	https://www.ncbi.nlm.nih.gov/pubmed/21194017	NUM
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dti-2185	418	18	https://www.ncbi.nlm.nih.gov/pubmed/11020766	https://www.ncbi.nlm.nih.gov/pubmed/11020766	NUM
dti-2185	418	19	https://doi.org/10.1159/000139246	https://doi.org/10.1159/000139246	NOUN
dti-2185	418	20	https://www.ncbi.nlm.nih.gov/pubmed/7862741	https://www.ncbi.nlm.nih.gov/pubmed/7862741	X
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dti-2185	419	1	https://doi.org/10.1093/bja/ael079	https://doi.org/10.1093/bja/ael079	PROPN
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dti-2185	419	4	https://www.ncbi.nlm.nih.gov/pubmed/11251643	https://www.ncbi.nlm.nih.gov/pubmed/11251643	X
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dti-2185	419	10	https://www.ncbi.nlm.nih.gov/pubmed/22542538	https://www.ncbi.nlm.nih.gov/pubmed/22542538	NOUN
dti-2185	419	11	https://doi.org/10.1016/j.bbamem.2019.183140	https://doi.org/10.1016/j.bbamem.2019.183140	PROPN
dti-2185	419	12	https://www.ncbi.nlm.nih.gov/pubmed/31790694	https://www.ncbi.nlm.nih.gov/pubmed/31790694	PROPN
dti-2185	419	13	https://doi.org/10.1021/la2035278	https://doi.org/10.1021/la2035278	PRON
dti-2185	419	14	https://www.ncbi.nlm.nih.gov/pubmed/21995557	https://www.ncbi.nlm.nih.gov/pubmed/21995557	PROPN
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dti-2185	419	16	https://www.ncbi.nlm.nih.gov/pubmed/22352350	https://www.ncbi.nlm.nih.gov/pubmed/22352350	X
dti-2185	419	17	https://doi.org/10.1021/jp411261	https://doi.org/10.1021/jp411261	X
dti-2185	419	18	g	g	NOUN
dti-2185	419	19	https://www.ncbi.nlm.nih.gov/pubmed/24299622	https://www.ncbi.nlm.nih.gov/pubmed/24299622	NUM
dti-2185	419	20	https://doi.org/10.1016/j.bbamem.2016.07.011	https://doi.org/10.1016/j.bbamem.2016.07.011	NOUN
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dti-2185	419	27	https://www.ncbi.nlm.nih.gov/pubmed/26423360	https://www.ncbi.nlm.nih.gov/pubmed/26423360	NUM
dti-2185	419	28	https://doi.org/10.1371/journal.pone.0040079	https://doi.org/10.1371/journal.pone.0040079	PROPN
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dti-2185	419	30	https://doi.org/10.1002/ajh.21126	https://doi.org/10.1002/ajh.21126	PROPN
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dti-2185	419	32	https://doi.org/10.1016/j.ejps.2012.10.023	https://doi.org/10.1016/j.ejps.2012.10.023	PROPN
dti-2185	419	33	https://www.ncbi.nlm.nih.gov/pubmed/23142844	https://www.ncbi.nlm.nih.gov/pubmed/23142844	NUM
dti-2185	419	34	interaction	interaction	NOUN
dti-2185	419	35	of	of	ADP
dti-2185	419	36	drugs	drug	NOUN
dti-2185	419	37	with	with	ADP
dti-2185	419	38	lipid	lipid	ADJ
dti-2185	419	39	rafts46	rafts46	NOUN
dti-2185	419	40	©	©	ADP
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dti-2185	419	43	authors	author	NOUN
dti-2185	419	44	.	.	PUNCT
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dti-2185	420	2	by	by	ADP
dti-2185	420	3	aboutscience	aboutscience	NOUN
dti-2185	420	4	45	45	NUM
dti-2185	420	5	.	.	PUNCT
dti-2185	421	1	yoshida	yoshida	PROPN
dti-2185	421	2	k	k	PROPN
dti-2185	421	3	,	,	PUNCT
dti-2185	421	4	takashima	takashima	PROPN
dti-2185	421	5	a	a	DET
dti-2185	421	6	,	,	PUNCT
dti-2185	421	7	nishio	nishio	PROPN
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dti-2185	421	11	dibucaine	dibucaine	ADJ
dti-2185	421	12	hydrochloride	hydrochloride	NOUN
dti-2185	421	13	on	on	ADP
dti-2185	421	14	raft	raft	NOUN
dti-2185	421	15	-	-	PUNCT
dti-2185	421	16	like	like	ADJ
dti-2185	421	17	lipid	lipid	NOUN
dti-2185	421	18	domains	domain	NOUN
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dti-2185	421	20	model	model	NOUN
dti-2185	421	21	membrane	membrane	NOUN
dti-2185	421	22	system	system	NOUN
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dti-2185	423	2	-	-	SYM
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dti-2185	423	4	.	.	PUNCT
dti-2185	424	1	crossref	crossref	PROPN
dti-2185	424	2	46	46	NUM
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dti-2185	425	3	,	,	PUNCT
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dti-2185	425	10	stability	stability	NOUN
dti-2185	425	11	of	of	ADP
dti-2185	425	12	phaseseparated	phaseseparate	VERB
dti-2185	425	13	domains	domain	NOUN
dti-2185	425	14	in	in	ADP
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dti-2185	425	16	lipid	lipid	NOUN
dti-2185	425	17	membranes	membrane	NOUN
dti-2185	425	18	with	with	ADP
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dti-2185	425	20	anesthetics	anesthetic	NOUN
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dti-2185	426	1	membranes	membrane	NOUN
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dti-2185	426	4	)	)	PUNCT
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dti-2185	427	3	crossref	crossref	PROPN
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dti-2185	428	17	raft	raft	NOUN
dti-2185	428	18	-	-	PUNCT
dti-2185	428	19	like	like	NOUN
dti-2185	428	20	ordered	order	VERB
dti-2185	428	21	membrane	membrane	NOUN
dti-2185	428	22	domains	domain	NOUN
dti-2185	428	23	.	.	PUNCT
dti-2185	429	1	biochim	biochim	PROPN
dti-2185	429	2	biophys	biophy	NOUN
dti-2185	429	3	acta	acta	PROPN
dti-2185	429	4	,	,	PUNCT
dti-2185	429	5	gen	gen	PROPN
dti-2185	429	6	subj	subj	NOUN
dti-2185	429	7	.	.	PUNCT
dti-2185	430	1	2019;1863(9):13811389	2019;1863(9):13811389	X
dti-2185	430	2	.	.	PUNCT
dti-2185	431	1	crossref	crossref	PROPN
dti-2185	431	2	medline	medline	NOUN
dti-2185	431	3	48	48	NUM
dti-2185	431	4	.	.	PUNCT
dti-2185	432	1	groban	groban	PROPN
dti-2185	432	2	l	l	PROPN
dti-2185	432	3	,	,	PUNCT
dti-2185	432	4	deal	deal	NOUN
dti-2185	432	5	dd	dd	PROPN
dti-2185	432	6	,	,	PUNCT
dti-2185	432	7	vernon	vernon	PROPN
dti-2185	432	8	jc	jc	PROPN
dti-2185	432	9	,	,	PUNCT
dti-2185	432	10	james	james	PROPN
dti-2185	432	11	rl	rl	PROPN
dti-2185	432	12	,	,	PUNCT
dti-2185	432	13	butterworth	butterworth	PROPN
dti-2185	432	14	j.	j.	PROPN
dti-2185	432	15	cardiac	cardiac	PROPN
dti-2185	432	16	resuscitation	resuscitation	NOUN
dti-2185	432	17	after	after	ADP
dti-2185	432	18	incremental	incremental	ADJ
dti-2185	432	19	overdosage	overdosage	NOUN
dti-2185	432	20	with	with	ADP
dti-2185	432	21	lidocaine	lidocaine	NOUN
dti-2185	432	22	,	,	PUNCT
dti-2185	432	23	bupivacaine	bupivacaine	NOUN
dti-2185	432	24	,	,	PUNCT
dti-2185	432	25	levobupivacaine	levobupivacaine	NOUN
dti-2185	432	26	,	,	PUNCT
dti-2185	432	27	and	and	CCONJ
dti-2185	432	28	ropivacaine	ropivacaine	VERB
dti-2185	432	29	in	in	ADP
dti-2185	432	30	anesthetized	anesthetize	VERB
dti-2185	432	31	dogs	dog	NOUN
dti-2185	432	32	.	.	PUNCT
dti-2185	433	1	anesth	anesth	PROPN
dti-2185	433	2	analg	analg	PROPN
dti-2185	433	3	.	.	PUNCT
dti-2185	434	1	2001;92(1):37	2001;92(1):37	NUM
dti-2185	434	2	-	-	SYM
dti-2185	434	3	43	43	NUM
dti-2185	434	4	.	.	PUNCT
dti-2185	435	1	crossref	crossref	PROPN
dti-2185	435	2	medline	medline	NOUN
dti-2185	435	3	49	49	NUM
dti-2185	435	4	.	.	PUNCT
dti-2185	436	1	tsuchiya	tsuchiya	PROPN
dti-2185	436	2	h	h	PROPN
dti-2185	436	3	,	,	PUNCT
dti-2185	436	4	ueno	ueno	PROPN
dti-2185	436	5	t	t	PROPN
dti-2185	436	6	,	,	PUNCT
dti-2185	436	7	mizogami	mizogami	PROPN
dti-2185	436	8	m	m	PROPN
dti-2185	436	9	,	,	PUNCT
dti-2185	436	10	takakura	takakura	PROPN
dti-2185	436	11	k.	k.	PROPN
dti-2185	436	12	do	do	AUX
dti-2185	436	13	local	local	ADJ
dti-2185	436	14	anesthetics	anesthetic	NOUN
dti-2185	436	15	interact	interact	VERB
dti-2185	436	16	preferentially	preferentially	ADV
dti-2185	436	17	with	with	ADP
dti-2185	436	18	membrane	membrane	NOUN
dti-2185	436	19	lipid	lipid	NOUN
dti-2185	436	20	rafts	raft	NOUN
dti-2185	436	21	?	?	PUNCT
dti-2185	437	1	comparative	comparative	ADJ
dti-2185	437	2	interactivities	interactivitie	NOUN
dti-2185	437	3	with	with	ADP
dti-2185	437	4	raft	raft	NOUN
dti-2185	437	5	-	-	PUNCT
dti-2185	437	6	like	like	ADJ
dti-2185	437	7	membranes	membrane	NOUN
dti-2185	437	8	.	.	PUNCT
dti-2185	438	1	j	j	PROPN
dti-2185	438	2	anesth	anesth	PROPN
dti-2185	438	3	.	.	PUNCT
dti-2185	439	1	2010;24(4):639	2010;24(4):639	PROPN
dti-2185	439	2	-	-	PUNCT
dti-2185	439	3	642	642	NUM
dti-2185	439	4	.	.	PUNCT
dti-2185	440	1	crossref	crossref	PROPN
dti-2185	440	2	medline	medline	PROPN
dti-2185	440	3	50	50	NUM
dti-2185	440	4	.	.	PUNCT
dti-2185	441	1	tsuchiya	tsuchiya	PROPN
dti-2185	441	2	h	h	PROPN
dti-2185	441	3	,	,	PUNCT
dti-2185	441	4	mizogami	mizogami	PROPN
dti-2185	441	5	m.	m.	PROPN
dti-2185	441	6	r(+)-	r(+)-	PROPN
dti-2185	441	7	,	,	PUNCT
dti-2185	441	8	rac-	rac-	NOUN
dti-2185	441	9	,	,	PUNCT
dti-2185	441	10	and	and	CCONJ
dti-2185	441	11	s(-)-bupivacaine	s(-)-bupivacaine	ADP
dti-2185	441	12	stereostructure	stereostructure	NOUN
dti-2185	441	13	-	-	PUNCT
dti-2185	441	14	specifically	specifically	ADV
dti-2185	441	15	interact	interact	VERB
dti-2185	441	16	with	with	ADP
dti-2185	441	17	membrane	membrane	NOUN
dti-2185	441	18	lipids	lipid	NOUN
dti-2185	441	19	at	at	ADP
dti-2185	441	20	cardiotoxically	cardiotoxically	ADV
dti-2185	441	21	relevant	relevant	ADJ
dti-2185	441	22	concentrations	concentration	NOUN
dti-2185	441	23	.	.	PUNCT
dti-2185	442	1	anesth	anesth	PROPN
dti-2185	442	2	analg	analg	PROPN
dti-2185	442	3	.	.	PUNCT
dti-2185	443	1	2012;114(2	2012;114(2	NUM
dti-2185	443	2	):	):	PUNCT
dti-2185	443	3	310	310	NUM
dti-2185	443	4	-	-	SYM
dti-2185	443	5	312	312	NUM
dti-2185	443	6	.	.	PUNCT
dti-2185	443	7	crossref	crossref	PROPN
dti-2185	443	8	medline	medline	NOUN
dti-2185	443	9	51	51	NUM
dti-2185	443	10	.	.	PUNCT
dti-2185	444	1	pontier	pontier	NOUN
dti-2185	444	2	sm	sm	PROPN
dti-2185	444	3	,	,	PUNCT
dti-2185	444	4	percherancier	percherancier	NOUN
dti-2185	444	5	y	y	PROPN
dti-2185	444	6	,	,	PUNCT
dti-2185	444	7	galandrin	galandrin	PROPN
dti-2185	444	8	s	s	PROPN
dti-2185	444	9	,	,	PUNCT
dti-2185	444	10	breit	breit	NOUN
dti-2185	444	11	a	a	X
dti-2185	444	12	,	,	PUNCT
dti-2185	444	13	galés	galés	NOUN
dti-2185	444	14	c	c	NOUN
dti-2185	444	15	,	,	PUNCT
dti-2185	444	16	bouvier	bouvier	ADJ
dti-2185	444	17	m.	m.	NOUN
dti-2185	444	18	cholesterol	cholesterol	NOUN
dti-2185	444	19	-	-	PUNCT
dti-2185	444	20	dependent	dependent	ADJ
dti-2185	444	21	separation	separation	NOUN
dti-2185	444	22	of	of	ADP
dti-2185	444	23	the	the	DET
dti-2185	444	24	β	β	PROPN
dti-2185	444	25	2	2	NUM
dti-2185	444	26	-	-	PUNCT
dti-2185	444	27	adrenergic	adrenergic	ADJ
dti-2185	444	28	receptor	receptor	NOUN
dti-2185	444	29	from	from	ADP
dti-2185	444	30	its	its	PRON
dti-2185	444	31	partners	partner	NOUN
dti-2185	444	32	determines	determine	VERB
dti-2185	444	33	signaling	signal	VERB
dti-2185	444	34	efficacy	efficacy	NOUN
dti-2185	444	35	:	:	PUNCT
dti-2185	444	36	insight	insight	NOUN
dti-2185	444	37	into	into	ADP
dti-2185	444	38	nanoscale	nanoscale	NOUN
dti-2185	444	39	organization	organization	NOUN
dti-2185	444	40	of	of	ADP
dti-2185	444	41	signal	signal	ADJ
dti-2185	444	42	transduction	transduction	NOUN
dti-2185	444	43	.	.	PUNCT
dti-2185	445	1	j	j	PROPN
dti-2185	445	2	biol	biol	PROPN
dti-2185	445	3	chem	chem	NOUN
dti-2185	445	4	.	.	PUNCT
dti-2185	446	1	2008;283(36):24659	2008;283(36):24659	NUM
dti-2185	446	2	-	-	SYM
dti-2185	446	3	24672	24672	NUM
dti-2185	446	4	.	.	PUNCT
dti-2185	447	1	crossref	crossref	PROPN
dti-2185	447	2	medline	medline	NOUN
dti-2185	447	3	52	52	NUM
dti-2185	447	4	.	.	PUNCT
dti-2185	448	1	mizogami	mizogami	PROPN
dti-2185	448	2	m	m	PROPN
dti-2185	448	3	,	,	PUNCT
dti-2185	448	4	takakura	takakura	PROPN
dti-2185	448	5	k	k	PROPN
dti-2185	448	6	,	,	PUNCT
dti-2185	448	7	tsuchiya	tsuchiya	PROPN
dti-2185	448	8	h.	h.	PROPN
dti-2185	449	1	the	the	DET
dti-2185	449	2	interactivities	interactivitie	NOUN
dti-2185	449	3	with	with	ADP
dti-2185	449	4	lipid	lipid	NOUN
dti-2185	449	5	membranes	membrane	NOUN
dti-2185	449	6	differentially	differentially	ADV
dti-2185	449	7	characterize	characterize	VERB
dti-2185	449	8	selective	selective	ADJ
dti-2185	449	9	and	and	CCONJ
dti-2185	449	10	nonselective	nonselective	ADJ
dti-2185	449	11	β1	β1	NOUN
dti-2185	449	12	-	-	PUNCT
dti-2185	449	13	blockers	blocker	NOUN
dti-2185	449	14	.	.	PUNCT
dti-2185	450	1	eur	eur	PROPN
dti-2185	450	2	j	j	PROPN
dti-2185	450	3	anaesthesiol	anaesthesiol	PROPN
dti-2185	450	4	.	.	PUNCT
dti-2185	451	1	2010;27(9):829	2010;27(9):829	NUM
dti-2185	451	2	-	-	SYM
dti-2185	451	3	834	834	NUM
dti-2185	451	4	.	.	PUNCT
dti-2185	451	5	crossref	crossref	PROPN
dti-2185	451	6	medline	medline	NOUN
dti-2185	451	7	53	53	NUM
dti-2185	451	8	.	.	PUNCT
dti-2185	452	1	tsuchiya	tsuchiya	PROPN
dti-2185	452	2	h	h	PROPN
dti-2185	452	3	,	,	PUNCT
dti-2185	452	4	mizogami	mizogami	PROPN
dti-2185	452	5	m.	m.	NOUN
dti-2185	452	6	characteristic	characteristic	ADJ
dti-2185	452	7	interactivity	interactivity	NOUN
dti-2185	452	8	of	of	ADP
dti-2185	452	9	landiolol	landiolol	PROPN
dti-2185	452	10	,	,	PUNCT
dti-2185	452	11	an	an	DET
dti-2185	452	12	ultra	ultra	ADJ
dti-2185	452	13	-	-	ADJ
dti-2185	452	14	short	short	ADJ
dti-2185	452	15	-	-	PUNCT
dti-2185	452	16	acting	act	VERB
dti-2185	452	17	highly	highly	ADV
dti-2185	452	18	selective	selective	ADJ
dti-2185	452	19	β1	β1	NOUN
dti-2185	452	20	-	-	PUNCT
dti-2185	452	21	blocker	blocker	NOUN
dti-2185	452	22	,	,	PUNCT
dti-2185	452	23	with	with	ADP
dti-2185	452	24	biomimetic	biomimetic	ADJ
dti-2185	452	25	membranes	membrane	NOUN
dti-2185	452	26	:	:	PUNCT
dti-2185	452	27	comparisons	comparison	NOUN
dti-2185	452	28	with	with	ADP
dti-2185	452	29	β1	β1	NOUN
dti-2185	452	30	-	-	PUNCT
dti-2185	452	31	selective	selective	ADJ
dti-2185	452	32	esmolol	esmolol	NOUN
dti-2185	452	33	and	and	CCONJ
dti-2185	452	34	non	non	ADJ
dti-2185	452	35	-	-	ADJ
dti-2185	452	36	selective	selective	ADJ
dti-2185	452	37	propranolol	propranolol	NOUN
dti-2185	452	38	and	and	CCONJ
dti-2185	452	39	alprenolol	alprenolol	NOUN
dti-2185	452	40	.	.	PUNCT
dti-2185	453	1	front	front	ADJ
dti-2185	453	2	pharmacol	pharmacol	PROPN
dti-2185	453	3	.	.	PUNCT
dti-2185	454	1	2013;4:150	2013;4:150	NUM
dti-2185	454	2	.	.	PUNCT
dti-2185	455	1	crossref	crossref	PROPN
dti-2185	455	2	medline	medline	NOUN
dti-2185	455	3	54	54	NUM
dti-2185	455	4	.	.	PUNCT
dti-2185	456	1	prichard	prichard	PROPN
dti-2185	456	2	bn	bn	PROPN
dti-2185	456	3	,	,	PUNCT
dti-2185	456	4	cruickshank	cruickshank	PROPN
dti-2185	456	5	jm	jm	PROPN
dti-2185	456	6	,	,	PUNCT
dti-2185	456	7	graham	graham	PROPN
dti-2185	456	8	br	br	PROPN
dti-2185	456	9	.	.	PUNCT
dti-2185	457	1	beta	beta	NOUN
dti-2185	457	2	-	-	PUNCT
dti-2185	457	3	adrenergic	adrenergic	NOUN
dti-2185	457	4	blocking	block	VERB
dti-2185	457	5	drugs	drug	NOUN
dti-2185	457	6	in	in	ADP
dti-2185	457	7	the	the	DET
dti-2185	457	8	treatment	treatment	NOUN
dti-2185	457	9	of	of	ADP
dti-2185	457	10	hypertension	hypertension	NOUN
dti-2185	457	11	.	.	PUNCT
dti-2185	458	1	blood	blood	NOUN
dti-2185	458	2	press	press	NOUN
dti-2185	458	3	.	.	PUNCT
dti-2185	459	1	2001;10(5	2001;10(5	NUM
dti-2185	459	2	-	-	PUNCT
dti-2185	459	3	6):366	6):366	NUM
dti-2185	459	4	-	-	PUNCT
dti-2185	459	5	386	386	NUM
dti-2185	459	6	.	.	PUNCT
dti-2185	459	7	crossref	crossref	PROPN
dti-2185	459	8	medline	medline	NOUN
dti-2185	459	9	55	55	NUM
dti-2185	459	10	.	.	PUNCT
dti-2185	460	1	callera	callera	PROPN
dti-2185	460	2	ge	ge	PROPN
dti-2185	460	3	,	,	PUNCT
dti-2185	460	4	montezano	montezano	PROPN
dti-2185	460	5	ac	ac	PROPN
dti-2185	460	6	,	,	PUNCT
dti-2185	460	7	yogi	yogi	NOUN
dti-2185	460	8	a	a	PRON
dti-2185	460	9	,	,	PUNCT
dti-2185	460	10	tostes	tostes	PROPN
dti-2185	460	11	rc	rc	PROPN
dti-2185	460	12	,	,	PUNCT
dti-2185	460	13	touyz	touyz	PROPN
dti-2185	460	14	rm	rm	PROPN
dti-2185	460	15	.	.	PUNCT
dti-2185	460	16	vascular	vascular	PROPN
dti-2185	460	17	signaling	signal	VERB
dti-2185	460	18	through	through	ADP
dti-2185	460	19	cholesterol	cholesterol	NOUN
dti-2185	460	20	-	-	PUNCT
dti-2185	460	21	rich	rich	ADJ
dti-2185	460	22	domains	domain	NOUN
dti-2185	460	23	:	:	PUNCT
dti-2185	460	24	implications	implication	NOUN
dti-2185	460	25	in	in	ADP
dti-2185	460	26	hypertension	hypertension	NOUN
dti-2185	460	27	.	.	PUNCT
dti-2185	461	1	curr	curr	PROPN
dti-2185	461	2	opin	opin	NOUN
dti-2185	461	3	nephrol	nephrol	NOUN
dti-2185	461	4	hypertens	hyperten	NOUN
dti-2185	461	5	.	.	PUNCT
dti-2185	462	1	2007;16(2):90104	2007;16(2):90104	PROPN
dti-2185	462	2	.	.	PUNCT
dti-2185	463	1	crossref	crossref	PROPN
dti-2185	463	2	medline	medline	PROPN
dti-2185	463	3	56	56	NUM
dti-2185	463	4	.	.	PUNCT
dti-2185	464	1	mizogami	mizogami	PROPN
dti-2185	464	2	m	m	PROPN
dti-2185	464	3	,	,	PUNCT
dti-2185	464	4	tsuchiya	tsuchiya	PROPN
dti-2185	464	5	h.	h.	PROPN
dti-2185	464	6	membrane	membrane	NOUN
dti-2185	464	7	interactivity	interactivity	NOUN
dti-2185	464	8	of	of	ADP
dti-2185	464	9	anesthetic	anesthetic	ADJ
dti-2185	464	10	adjuvant	adjuvant	NOUN
dti-2185	464	11	dexmedetomidine	dexmedetomidine	PROPN
dti-2185	464	12	discriminable	discriminable	ADJ
dti-2185	464	13	from	from	ADP
dti-2185	464	14	clonidine	clonidine	PROPN
dti-2185	464	15	and	and	CCONJ
dti-2185	464	16	enantiomeric	enantiomeric	ADJ
dti-2185	464	17	levomedetomidine	levomedetomidine	PROPN
dti-2185	464	18	.	.	PUNCT
dti-2185	465	1	j	j	PROPN
dti-2185	465	2	adv	adv	PROPN
dti-2185	465	3	med	me	VERB
dti-2185	465	4	med	med	ADJ
dti-2185	465	5	res	re	NOUN
dti-2185	465	6	.	.	PUNCT
dti-2185	466	1	2019;29:1	2019;29:1	NOUN
dti-2185	466	2	-	-	PUNCT
dti-2185	466	3	15	15	NUM
dti-2185	466	4	.	.	PUNCT
dti-2185	467	1	crossref	crossref	PROPN
dti-2185	467	2	57	57	NUM
dti-2185	467	3	.	.	PUNCT
dti-2185	468	1	morris	morris	PROPN
dti-2185	468	2	dp	dp	PROPN
dti-2185	468	3	,	,	PUNCT
dti-2185	468	4	lei	lei	PROPN
dti-2185	468	5	b	b	PROPN
dti-2185	468	6	,	,	PUNCT
dti-2185	468	7	wu	wu	PROPN
dti-2185	468	8	yx	yx	PROPN
dti-2185	468	9	,	,	PUNCT
dti-2185	468	10	michelotti	michelotti	PROPN
dti-2185	468	11	ga	ga	PROPN
dti-2185	468	12	,	,	PUNCT
dti-2185	468	13	schwinn	schwinn	PROPN
dti-2185	468	14	da	da	PROPN
dti-2185	468	15	.	.	PUNCT
dti-2185	469	1	the	the	DET
dti-2185	469	2	α	α	PROPN
dti-2185	469	3	1aadrenergic	1aadrenergic	PROPN
dti-2185	469	4	receptor	receptor	NOUN
dti-2185	469	5	occupies	occupy	VERB
dti-2185	469	6	membrane	membrane	NOUN
dti-2185	469	7	rafts	raft	NOUN
dti-2185	469	8	with	with	ADP
dti-2185	469	9	its	its	PRON
dti-2185	469	10	g	g	NOUN
dti-2185	469	11	protein	protein	NOUN
dti-2185	469	12	effectors	effector	NOUN
dti-2185	469	13	but	but	CCONJ
dti-2185	469	14	internalizes	internalize	VERB
dti-2185	469	15	via	via	ADP
dti-2185	469	16	clathrin	clathrin	NOUN
dti-2185	469	17	-	-	PUNCT
dti-2185	469	18	coated	coat	VERB
dti-2185	469	19	pits	pit	NOUN
dti-2185	469	20	.	.	PUNCT
dti-2185	470	1	j	j	PROPN
dti-2185	470	2	biol	biol	PROPN
dti-2185	470	3	chem	chem	NOUN
dti-2185	470	4	.	.	PUNCT
dti-2185	471	1	2008;283(5):2973	2008;283(5):2973	NUM
dti-2185	471	2	-	-	SYM
dti-2185	471	3	2985	2985	NUM
dti-2185	471	4	.	.	PUNCT
dti-2185	472	1	crossref	crossref	PROPN
dti-2185	472	2	medline	medline	NOUN
dti-2185	473	1	58	58	NUM
dti-2185	473	2	.	.	PUNCT
dti-2185	474	1	huang	huang	PROPN
dti-2185	474	2	p	p	PROPN
dti-2185	474	3	,	,	PUNCT
dti-2185	474	4	xu	xu	PROPN
dti-2185	474	5	w	w	PROPN
dti-2185	474	6	,	,	PUNCT
dti-2185	474	7	yoon	yoon	PROPN
dti-2185	474	8	si	si	PROPN
dti-2185	474	9	,	,	PUNCT
dti-2185	474	10	et	et	PROPN
dti-2185	474	11	al	al	PROPN
dti-2185	474	12	.	.	PUNCT
dti-2185	475	1	agonist	agonist	NOUN
dti-2185	475	2	treatment	treatment	NOUN
dti-2185	475	3	did	do	AUX
dti-2185	475	4	not	not	PART
dti-2185	475	5	affect	affect	VERB
dti-2185	475	6	association	association	NOUN
dti-2185	475	7	of	of	ADP
dti-2185	475	8	mu	mu	PROPN
dti-2185	475	9	opioid	opioid	ADJ
dti-2185	475	10	receptors	receptor	NOUN
dti-2185	475	11	with	with	ADP
dti-2185	475	12	lipid	lipid	ADJ
dti-2185	475	13	rafts	raft	NOUN
dti-2185	475	14	and	and	CCONJ
dti-2185	475	15	cholesterol	cholesterol	NOUN
dti-2185	475	16	reduction	reduction	NOUN
dti-2185	475	17	had	have	VERB
dti-2185	475	18	opposite	opposite	ADJ
dti-2185	475	19	effects	effect	NOUN
dti-2185	475	20	on	on	ADP
dti-2185	475	21	the	the	DET
dti-2185	475	22	receptor	receptor	NOUN
dti-2185	475	23	-	-	PUNCT
dti-2185	475	24	mediated	mediate	VERB
dti-2185	475	25	signaling	signal	VERB
dti-2185	475	26	in	in	ADP
dti-2185	475	27	rat	rat	NOUN
dti-2185	475	28	brain	brain	NOUN
dti-2185	475	29	and	and	CCONJ
dti-2185	475	30	cho	cho	NOUN
dti-2185	475	31	cells	cell	NOUN
dti-2185	475	32	.	.	PUNCT
dti-2185	476	1	brain	brain	NOUN
dti-2185	476	2	res	re	NOUN
dti-2185	476	3	.	.	PUNCT
dti-2185	477	1	2007;1184:4656	2007;1184:4656	NUM
dti-2185	477	2	.	.	PUNCT
dti-2185	478	1	crossref	crossref	PROPN
dti-2185	478	2	medline	medline	PROPN
dti-2185	478	3	59	59	NUM
dti-2185	478	4	.	.	PUNCT
dti-2185	479	1	heron	heron	PROPN
dti-2185	479	2	ds	ds	PROPN
dti-2185	479	3	,	,	PUNCT
dti-2185	479	4	shinitzky	shinitzky	NOUN
dti-2185	479	5	m	m	PROPN
dti-2185	479	6	,	,	PUNCT
dti-2185	479	7	zamir	zamir	PROPN
dti-2185	479	8	n	n	PROPN
dti-2185	479	9	,	,	PUNCT
dti-2185	479	10	samuel	samuel	PROPN
dti-2185	479	11	d.	d.	PROPN
dti-2185	479	12	adaptive	adaptive	PROPN
dti-2185	479	13	modulations	modulation	NOUN
dti-2185	479	14	of	of	ADP
dti-2185	479	15	brain	brain	NOUN
dti-2185	479	16	membrane	membrane	NOUN
dti-2185	479	17	lipid	lipid	NOUN
dti-2185	479	18	fluidity	fluidity	NOUN
dti-2185	479	19	in	in	ADP
dti-2185	479	20	drug	drug	NOUN
dti-2185	479	21	addiction	addiction	NOUN
dti-2185	479	22	and	and	CCONJ
dti-2185	479	23	denervation	denervation	NOUN
dti-2185	479	24	supersensitivity	supersensitivity	NOUN
dti-2185	479	25	.	.	PUNCT
dti-2185	480	1	biochem	biochem	PROPN
dti-2185	480	2	pharmacol	pharmacol	PROPN
dti-2185	480	3	.	.	PUNCT
dti-2185	481	1	1982;31(14):2435	1982;31(14):2435	NUM
dti-2185	481	2	-	-	SYM
dti-2185	481	3	2438	2438	NUM
dti-2185	481	4	.	.	PUNCT
dti-2185	482	1	crossref	crossref	PROPN
dti-2185	482	2	medline	medline	PROPN
dti-2185	482	3	60	60	NUM
dti-2185	482	4	.	.	PUNCT
dti-2185	483	1	budai	budai	PROPN
dti-2185	483	2	m	m	PROPN
dti-2185	483	3	,	,	PUNCT
dti-2185	483	4	szabó	szabó	PROPN
dti-2185	483	5	z	z	PROPN
dti-2185	483	6	,	,	PUNCT
dti-2185	483	7	szogyi	szogyi	PROPN
dti-2185	483	8	m	m	PROPN
dti-2185	483	9	,	,	PUNCT
dti-2185	483	10	gróf	gróf	NOUN
dti-2185	484	1	p.	p.	NOUN
dti-2185	484	2	molecular	molecular	ADJ
dti-2185	484	3	interactions	interaction	NOUN
dti-2185	484	4	between	between	ADP
dti-2185	484	5	dppc	dppc	NOUN
dti-2185	484	6	and	and	CCONJ
dti-2185	484	7	morphine	morphine	NOUN
dti-2185	484	8	derivatives	derivative	NOUN
dti-2185	484	9	:	:	PUNCT
dti-2185	484	10	a	a	DET
dti-2185	484	11	dsc	dsc	PROPN
dti-2185	484	12	and	and	CCONJ
dti-2185	484	13	epr	epr	PROPN
dti-2185	484	14	study	study	PROPN
dti-2185	484	15	.	.	PUNCT
dti-2185	485	1	int	int	PROPN
dti-2185	485	2	j	j	PROPN
dti-2185	485	3	pharm	pharm	PROPN
dti-2185	485	4	.	.	PUNCT
dti-2185	486	1	2003;250:239–250	2003;250:239–250	NUM
dti-2185	486	2	.	.	PUNCT
dti-2185	487	1	crossref	crossref	PROPN
dti-2185	487	2	61	61	NUM
dti-2185	487	3	.	.	PUNCT
dti-2185	488	1	zheng	zheng	PROPN
dti-2185	488	2	h	h	PROPN
dti-2185	488	3	,	,	PUNCT
dti-2185	488	4	chu	chu	PROPN
dti-2185	488	5	j	j	PROPN
dti-2185	488	6	,	,	PUNCT
dti-2185	488	7	qiu	qiu	PROPN
dti-2185	488	8	y	y	PROPN
dti-2185	488	9	,	,	PUNCT
dti-2185	488	10	loh	loh	PROPN
dti-2185	488	11	hh	hh	PROPN
dti-2185	488	12	,	,	PUNCT
dti-2185	488	13	law	law	NOUN
dti-2185	488	14	py	py	NOUN
dti-2185	488	15	.	.	PUNCT
dti-2185	489	1	agonist	agonist	NOUN
dti-2185	489	2	-	-	PUNCT
dti-2185	489	3	selective	selective	ADJ
dti-2185	489	4	signaling	signaling	NOUN
dti-2185	489	5	is	be	AUX
dti-2185	489	6	determined	determine	VERB
dti-2185	489	7	by	by	ADP
dti-2185	489	8	the	the	DET
dti-2185	489	9	receptor	receptor	NOUN
dti-2185	489	10	location	location	NOUN
dti-2185	489	11	within	within	ADP
dti-2185	489	12	the	the	DET
dti-2185	489	13	membrane	membrane	NOUN
dti-2185	489	14	domains	domain	NOUN
dti-2185	489	15	.	.	PUNCT
dti-2185	490	1	proc	proc	PROPN
dti-2185	490	2	natl	natl	PROPN
dti-2185	490	3	acad	acad	PROPN
dti-2185	490	4	sci	sci	PROPN
dti-2185	490	5	usa	usa	PROPN
dti-2185	490	6	.	.	PROPN
dti-2185	491	1	2008;105(27):9421	2008;105(27):9421	PROPN
dti-2185	491	2	-	-	PUNCT
dti-2185	491	3	9426	9426	NUM
dti-2185	491	4	.	.	PUNCT
dti-2185	492	1	crossref	crossref	PROPN
dti-2185	492	2	medline	medline	PROPN
dti-2185	492	3	62	62	NUM
dti-2185	492	4	.	.	PUNCT
dti-2185	493	1	liou	liou	PROPN
dti-2185	493	2	jy	jy	PROPN
dti-2185	493	3	,	,	PUNCT
dti-2185	493	4	deng	deng	PROPN
dti-2185	493	5	wg	wg	PROPN
dti-2185	493	6	,	,	PUNCT
dti-2185	493	7	gilroy	gilroy	PROPN
dti-2185	493	8	dw	dw	PROPN
dti-2185	493	9	,	,	PUNCT
dti-2185	493	10	shyue	shyue	VERB
dti-2185	493	11	sk	sk	ADP
dti-2185	493	12	,	,	PUNCT
dti-2185	493	13	wu	wu	PROPN
dti-2185	493	14	kk	kk	PROPN
dti-2185	493	15	.	.	PROPN
dti-2185	493	16	colocalization	colocalization	NOUN
dti-2185	493	17	and	and	CCONJ
dti-2185	493	18	interaction	interaction	NOUN
dti-2185	493	19	of	of	ADP
dti-2185	493	20	cyclooxygenase-2	cyclooxygenase-2	NUM
dti-2185	493	21	with	with	ADP
dti-2185	493	22	caveolin-1	caveolin-1	NUM
dti-2185	493	23	in	in	ADP
dti-2185	493	24	human	human	ADJ
dti-2185	493	25	fibroblasts	fibroblast	NOUN
dti-2185	493	26	.	.	PUNCT
dti-2185	494	1	j	j	PROPN
dti-2185	494	2	biol	biol	PROPN
dti-2185	494	3	chem	chem	NOUN
dti-2185	494	4	.	.	PUNCT
dti-2185	495	1	2001;276(37):34975	2001;276(37):34975	NUM
dti-2185	495	2	-	-	SYM
dti-2185	495	3	34982	34982	NUM
dti-2185	495	4	.	.	PUNCT
dti-2185	496	1	crossref	crossref	PROPN
dti-2185	496	2	medline	medline	PROPN
dti-2185	496	3	63	63	NUM
dti-2185	496	4	.	.	PUNCT
dti-2185	497	1	alsop	alsop	PROPN
dti-2185	497	2	rj	rj	PROPN
dti-2185	497	3	,	,	PUNCT
dti-2185	497	4	toppozini	toppozini	PROPN
dti-2185	497	5	l	l	NOUN
dti-2185	497	6	,	,	PUNCT
dti-2185	497	7	marquardt	marquardt	PROPN
dti-2185	497	8	d	d	PROPN
dti-2185	497	9	,	,	PUNCT
dti-2185	497	10	kučerka	kučerka	PROPN
dti-2185	497	11	n	n	CCONJ
dti-2185	497	12	,	,	PUNCT
dti-2185	497	13	harroun	harroun	NOUN
dti-2185	497	14	ta	ta	PROPN
dti-2185	497	15	,	,	PUNCT
dti-2185	497	16	rheinstädter	rheinstädter	PROPN
dti-2185	497	17	mc	mc	PROPN
dti-2185	497	18	.	.	PROPN
dti-2185	497	19	aspirin	aspirin	PROPN
dti-2185	497	20	inhibits	inhibit	VERB
dti-2185	497	21	formation	formation	NOUN
dti-2185	497	22	of	of	ADP
dti-2185	497	23	cholesterol	cholesterol	NOUN
dti-2185	497	24	rafts	raft	NOUN
dti-2185	497	25	in	in	ADP
dti-2185	497	26	fluid	fluid	ADJ
dti-2185	497	27	lipid	lipid	NOUN
dti-2185	497	28	membranes	membrane	NOUN
dti-2185	497	29	.	.	PUNCT
dti-2185	498	1	biochim	biochim	PROPN
dti-2185	498	2	biophys	biophy	NOUN
dti-2185	498	3	acta	acta	PROPN
dti-2185	498	4	.	.	PUNCT
dti-2185	499	1	2015;1848(3):805	2015;1848(3):805	NUM
dti-2185	499	2	-	-	PUNCT
dti-2185	499	3	812	812	NUM
dti-2185	499	4	.	.	PUNCT
dti-2185	499	5	crossref	crossref	PROPN
dti-2185	499	6	medline	medline	NOUN
dti-2185	499	7	64	64	NUM
dti-2185	499	8	.	.	PUNCT
dti-2185	500	1	alsop	alsop	PROPN
dti-2185	500	2	rj	rj	PROPN
dti-2185	500	3	,	,	PUNCT
dti-2185	500	4	himbert	himbert	PROPN
dti-2185	500	5	s	s	PROPN
dti-2185	500	6	,	,	PUNCT
dti-2185	500	7	dhaliwal	dhaliwal	PROPN
dti-2185	500	8	a	a	PRON
dti-2185	500	9	,	,	PUNCT
dti-2185	500	10	schmalzl	schmalzl	NOUN
dti-2185	500	11	k	k	NOUN
dti-2185	500	12	,	,	PUNCT
dti-2185	500	13	rheinstädter	rheinstädter	PROPN
dti-2185	500	14	mc	mc	PROPN
dti-2185	500	15	.	.	PROPN
dti-2185	500	16	aspirin	aspirin	PROPN
dti-2185	500	17	locally	locally	ADV
dti-2185	500	18	disrupts	disrupt	VERB
dti-2185	500	19	the	the	DET
dti-2185	500	20	liquid	liquid	NOUN
dti-2185	500	21	-	-	PUNCT
dti-2185	500	22	ordered	order	VERB
dti-2185	500	23	phase	phase	NOUN
dti-2185	500	24	.	.	PUNCT
dti-2185	501	1	r	r	NOUN
dti-2185	501	2	soc	soc	NOUN
dti-2185	501	3	open	open	VERB
dti-2185	501	4	sci	sci	PROPN
dti-2185	501	5	.	.	PUNCT
dti-2185	502	1	2018;5(2):171710	2018;5(2):171710	X
dti-2185	502	2	.	.	PUNCT
dti-2185	502	3	crossref	crossref	PROPN
dti-2185	502	4	medline	medline	PROPN
dti-2185	502	5	65	65	NUM
dti-2185	502	6	.	.	PUNCT
dti-2185	503	1	zhou	zhou	PROPN
dti-2185	503	2	y	y	PROPN
dti-2185	503	3	,	,	PUNCT
dti-2185	503	4	cho	cho	PROPN
dti-2185	503	5	kj	kj	PROPN
dti-2185	503	6	,	,	PUNCT
dti-2185	503	7	plowman	plowman	PROPN
dti-2185	503	8	sj	sj	PROPN
dti-2185	503	9	,	,	PUNCT
dti-2185	503	10	hancock	hancock	PROPN
dti-2185	503	11	jf	jf	PROPN
dti-2185	503	12	.	.	PROPN
dti-2185	503	13	nonsteroidal	nonsteroidal	NOUN
dti-2185	503	14	antiinflammatory	antiinflammatory	NOUN
dti-2185	503	15	drugs	drug	NOUN
dti-2185	503	16	alter	alter	VERB
dti-2185	503	17	the	the	DET
dti-2185	503	18	spatiotemporal	spatiotemporal	ADJ
dti-2185	503	19	organization	organization	NOUN
dti-2185	503	20	of	of	ADP
dti-2185	503	21	ras	ras	PROPN
dti-2185	503	22	proteins	protein	NOUN
dti-2185	503	23	on	on	ADP
dti-2185	503	24	the	the	DET
dti-2185	503	25	plasma	plasma	NOUN
dti-2185	503	26	membrane	membrane	NOUN
dti-2185	503	27	.	.	PUNCT
dti-2185	504	1	j	j	PROPN
dti-2185	504	2	biol	biol	PROPN
dti-2185	504	3	chem	chem	NOUN
dti-2185	504	4	.	.	PUNCT
dti-2185	505	1	2012;287(20):16586	2012;287(20):16586	NUM
dti-2185	505	2	-	-	NOUN
dti-2185	505	3	16595	16595	NUM
dti-2185	505	4	.	.	PUNCT
dti-2185	506	1	crossref	crossref	PROPN
dti-2185	506	2	medline	medline	NOUN
dti-2185	506	3	66	66	NUM
dti-2185	506	4	.	.	PUNCT
dti-2185	507	1	alves	alves	PROPN
dti-2185	507	2	acs	acs	PROPN
dti-2185	507	3	,	,	PUNCT
dti-2185	507	4	dias	dias	PROPN
dti-2185	507	5	ra	ra	PROPN
dti-2185	507	6	,	,	PUNCT
dti-2185	507	7	kagami	kagami	PROPN
dti-2185	507	8	lp	lp	PROPN
dti-2185	507	9	,	,	PUNCT
dti-2185	507	10	et	et	PROPN
dti-2185	507	11	al	al	PROPN
dti-2185	507	12	.	.	PROPN
dti-2185	508	1	beyond	beyond	ADP
dti-2185	508	2	the	the	DET
dti-2185	508	3	“	"	PUNCT
dti-2185	508	4	lock	lock	NOUN
dti-2185	508	5	and	and	CCONJ
dti-2185	508	6	key	key	ADJ
dti-2185	508	7	”	"	PUNCT
dti-2185	508	8	paradigm	paradigm	NOUN
dti-2185	508	9	:	:	PUNCT
dti-2185	508	10	targeting	target	VERB
dti-2185	508	11	lipid	lipid	NOUN
dti-2185	508	12	rafts	raft	NOUN
dti-2185	508	13	to	to	PART
dti-2185	508	14	induce	induce	VERB
dti-2185	508	15	the	the	DET
dti-2185	508	16	selective	selective	ADJ
dti-2185	508	17	apoptosis	apoptosis	NOUN
dti-2185	508	18	of	of	ADP
dti-2185	508	19	cancer	cancer	NOUN
dti-2185	508	20	cells	cell	NOUN
dti-2185	508	21	.	.	PUNCT
dti-2185	509	1	curr	curr	PROPN
dti-2185	509	2	med	med	PROPN
dti-2185	509	3	chem	chem	NOUN
dti-2185	509	4	.	.	PUNCT
dti-2185	510	1	2018;25(18):2082	2018;25(18):2082	NUM
dti-2185	510	2	-	-	SYM
dti-2185	510	3	2104	2104	NUM
dti-2185	510	4	.	.	PUNCT
dti-2185	511	1	crossref	crossref	PROPN
dti-2185	511	2	medline	medline	PROPN
dti-2185	511	3	67	67	NUM
dti-2185	511	4	.	.	PUNCT
dti-2185	512	1	van	van	PROPN
dti-2185	512	2	der	der	PROPN
dti-2185	512	3	luit	luit	PROPN
dti-2185	512	4	ah	ah	INTJ
dti-2185	512	5	,	,	PUNCT
dti-2185	512	6	vink	vink	PROPN
dti-2185	512	7	sr	sr	PROPN
dti-2185	512	8	,	,	PUNCT
dti-2185	512	9	klarenbeek	klarenbeek	PROPN
dti-2185	512	10	jb	jb	PROPN
dti-2185	512	11	,	,	PUNCT
dti-2185	512	12	et	et	PROPN
dti-2185	512	13	al	al	PROPN
dti-2185	512	14	.	.	PUNCT
dti-2185	513	1	a	a	DET
dti-2185	513	2	new	new	ADJ
dti-2185	513	3	class	class	NOUN
dti-2185	513	4	of	of	ADP
dti-2185	513	5	anticancer	anticancer	NOUN
dti-2185	513	6	alkylphospholipids	alkylphospholipid	NOUN
dti-2185	513	7	uses	use	VERB
dti-2185	513	8	lipid	lipid	NOUN
dti-2185	513	9	rafts	raft	NOUN
dti-2185	513	10	as	as	ADP
dti-2185	513	11	membrane	membrane	NOUN
dti-2185	513	12	gateways	gateway	NOUN
dti-2185	513	13	to	to	PART
dti-2185	513	14	induce	induce	VERB
dti-2185	513	15	apoptosis	apoptosis	NOUN
dti-2185	513	16	in	in	ADP
dti-2185	513	17	lymphoma	lymphoma	NOUN
dti-2185	513	18	cells	cell	NOUN
dti-2185	513	19	.	.	PUNCT
dti-2185	514	1	mol	mol	ADP
dti-2185	514	2	cancer	cancer	NOUN
dti-2185	514	3	ther	ther	ADV
dti-2185	514	4	.	.	PUNCT
dti-2185	515	1	2007;6(8):2337	2007;6(8):2337	NUM
dti-2185	515	2	-	-	SYM
dti-2185	515	3	2345	2345	NUM
dti-2185	515	4	.	.	PUNCT
dti-2185	516	1	crossref	crossref	PROPN
dti-2185	516	2	medline	medline	NOUN
dti-2185	516	3	68	68	NUM
dti-2185	516	4	.	.	PUNCT
dti-2185	517	1	alves	alves	PROPN
dti-2185	517	2	ac	ac	PROPN
dti-2185	517	3	,	,	PUNCT
dti-2185	517	4	ribeiro	ribeiro	PROPN
dti-2185	517	5	d	d	PROPN
dti-2185	517	6	,	,	PUNCT
dti-2185	517	7	nunes	nunes	PROPN
dti-2185	517	8	c	c	NOUN
dti-2185	517	9	,	,	PUNCT
dti-2185	517	10	reis	reis	NOUN
dti-2185	517	11	s.	s.	PROPN
dti-2185	517	12	biophysics	biophysics	PROPN
dti-2185	517	13	in	in	ADP
dti-2185	517	14	cancer	cancer	NOUN
dti-2185	517	15	:	:	PUNCT
dti-2185	517	16	the	the	DET
dti-2185	517	17	relevance	relevance	NOUN
dti-2185	517	18	of	of	ADP
dti-2185	517	19	drug	drug	NOUN
dti-2185	517	20	-	-	PUNCT
dti-2185	517	21	membrane	membrane	NOUN
dti-2185	517	22	interaction	interaction	NOUN
dti-2185	517	23	studies	study	NOUN
dti-2185	517	24	.	.	PUNCT
dti-2185	518	1	biochim	biochim	PROPN
dti-2185	518	2	biophys	biophy	NOUN
dti-2185	518	3	acta	acta	PROPN
dti-2185	518	4	.	.	PUNCT
dti-2185	519	1	2016;1858(9):2231	2016;1858(9):2231	NUM
dti-2185	519	2	-	-	PUNCT
dti-2185	519	3	2244	2244	NUM
dti-2185	519	4	.	.	PUNCT
dti-2185	520	1	crossref	crossref	PROPN
dti-2185	520	2	medline	medline	PROPN
dti-2185	520	3	69	69	NUM
dti-2185	520	4	.	.	PUNCT
dti-2185	521	1	ausili	ausili	PROPN
dti-2185	521	2	a	a	PRON
dti-2185	521	3	,	,	PUNCT
dti-2185	521	4	torrecillas	torrecillas	PROPN
dti-2185	521	5	a	a	PRON
dti-2185	521	6	,	,	PUNCT
dti-2185	521	7	aranda	aranda	PROPN
dti-2185	521	8	fj	fj	PROPN
dti-2185	521	9	,	,	PUNCT
dti-2185	522	1	et	et	PROPN
dti-2185	522	2	al	al	PROPN
dti-2185	522	3	.	.	PROPN
dti-2185	522	4	edelfosine	edelfosine	PROPN
dti-2185	522	5	is	be	AUX
dti-2185	522	6	incorporated	incorporate	VERB
dti-2185	522	7	into	into	ADP
dti-2185	522	8	rafts	raft	NOUN
dti-2185	522	9	and	and	CCONJ
dti-2185	522	10	alters	alter	VERB
dti-2185	522	11	their	their	PRON
dti-2185	522	12	organization	organization	NOUN
dti-2185	522	13	.	.	PUNCT
dti-2185	523	1	j	j	PROPN
dti-2185	523	2	phys	phys	PROPN
dti-2185	523	3	chem	chem	PROPN
dti-2185	523	4	b.	b.	PROPN
dti-2185	523	5	2008;112(37):11643	2008;112(37):11643	PROPN
dti-2185	523	6	-	-	SYM
dti-2185	523	7	11654	11654	NUM
dti-2185	523	8	.	.	PUNCT
dti-2185	524	1	crossref	crossref	PROPN
dti-2185	524	2	medline	medline	PROPN
dti-2185	524	3	70	70	NUM
dti-2185	524	4	.	.	PUNCT
dti-2185	525	1	gomide	gomide	PROPN
dti-2185	525	2	ab	ab	PROPN
dti-2185	525	3	,	,	PUNCT
dti-2185	525	4	thomé	thomé	ADJ
dti-2185	525	5	ch	ch	NOUN
dti-2185	525	6	,	,	PUNCT
dti-2185	525	7	dos	do	VERB
dti-2185	525	8	santos	santos	PROPN
dti-2185	525	9	ga	ga	PROPN
dti-2185	525	10	,	,	PUNCT
dti-2185	525	11	et	et	PROPN
dti-2185	525	12	al	al	PROPN
dti-2185	525	13	.	.	PUNCT
dti-2185	526	1	disrupting	disrupt	VERB
dti-2185	526	2	membrane	membrane	NOUN
dti-2185	526	3	raft	raft	NOUN
dti-2185	526	4	domains	domain	NOUN
dti-2185	526	5	by	by	ADP
dti-2185	526	6	alkylphospholipids	alkylphospholipid	NOUN
dti-2185	526	7	.	.	PUNCT
dti-2185	527	1	biochim	biochim	PROPN
dti-2185	527	2	biophys	biophy	NOUN
dti-2185	527	3	acta	acta	PROPN
dti-2185	527	4	.	.	PUNCT
dti-2185	528	1	2013;1828(5):1384	2013;1828(5):1384	NUM
dti-2185	528	2	-	-	SYM
dti-2185	528	3	1389	1389	NUM
dti-2185	528	4	.	.	PUNCT
dti-2185	529	1	crossref	crossref	PROPN
dti-2185	529	2	medline	medline	NOUN
dti-2185	529	3	71	71	NUM
dti-2185	529	4	.	.	PUNCT
dti-2185	530	1	castro	castro	PROPN
dti-2185	530	2	bm	bm	PROPN
dti-2185	530	3	,	,	PUNCT
dti-2185	530	4	fedorov	fedorov	PROPN
dti-2185	530	5	a	a	PRON
dti-2185	530	6	,	,	PUNCT
dti-2185	530	7	hornillos	hornillos	PROPN
dti-2185	530	8	v	v	PROPN
dti-2185	530	9	,	,	PUNCT
dti-2185	530	10	et	et	PROPN
dti-2185	530	11	al	al	PROPN
dti-2185	530	12	.	.	PROPN
dti-2185	530	13	edelfosine	edelfosine	PROPN
dti-2185	530	14	and	and	CCONJ
dti-2185	530	15	miltefosine	miltefosine	ADJ
dti-2185	530	16	effects	effect	NOUN
dti-2185	530	17	on	on	ADP
dti-2185	530	18	lipid	lipid	ADJ
dti-2185	530	19	raft	raft	NOUN
dti-2185	530	20	properties	property	NOUN
dti-2185	530	21	:	:	PUNCT
dti-2185	530	22	membrane	membrane	NOUN
dti-2185	530	23	biophysics	biophysic	NOUN
dti-2185	530	24	in	in	ADP
dti-2185	530	25	cell	cell	NOUN
dti-2185	530	26	death	death	NOUN
dti-2185	530	27	by	by	ADP
dti-2185	530	28	antitumor	antitumor	PROPN
dti-2185	530	29	lipids	lipids	PROPN
dti-2185	530	30	.	.	PUNCT
dti-2185	531	1	j	j	PROPN
dti-2185	531	2	phys	phys	PROPN
dti-2185	531	3	chem	chem	PROPN
dti-2185	531	4	b.	b.	PROPN
dti-2185	531	5	2013;117(26):79297940	2013;117(26):79297940	NUM
dti-2185	531	6	.	.	PUNCT
dti-2185	532	1	crossref	crossref	PROPN
dti-2185	532	2	medline	medline	PROPN
dti-2185	532	3	72	72	NUM
dti-2185	532	4	.	.	PUNCT
dti-2185	533	1	wnętrzak	wnętrzak	PROPN
dti-2185	533	2	a	a	PRON
dti-2185	533	3	,	,	PUNCT
dti-2185	533	4	łątka	łątka	PROPN
dti-2185	533	5	k	k	PROPN
dti-2185	533	6	,	,	PUNCT
dti-2185	533	7	makyła	makyła	ADJ
dti-2185	533	8	-	-	PUNCT
dti-2185	533	9	juzak	juzak	NOUN
dti-2185	533	10	k	k	PROPN
dti-2185	533	11	,	,	PUNCT
dti-2185	533	12	zemla	zemla	PROPN
dti-2185	533	13	j	j	PROPN
dti-2185	533	14	,	,	PUNCT
dti-2185	533	15	dynarowicz	dynarowicz	NOUN
dti-2185	533	16	-	-	PUNCT
dti-2185	533	17	łątka	łątka	NOUN
dti-2185	533	18	p.	p.	NOUN
dti-2185	533	19	the	the	DET
dti-2185	533	20	influence	influence	NOUN
dti-2185	533	21	of	of	ADP
dti-2185	533	22	an	an	DET
dti-2185	533	23	antitumor	antitumor	PROPN
dti-2185	533	24	lipid	lipid	NOUN
dti-2185	533	25	erucylphosphocholine	erucylphosphocholine	ADJ
dti-2185	533	26	on	on	ADP
dti-2185	533	27	artificial	artificial	ADJ
dti-2185	533	28	lipid	lipid	NOUN
dti-2185	533	29	raft	raft	NOUN
dti-2185	533	30	system	system	NOUN
dti-2185	533	31	modeled	model	VERB
dti-2185	533	32	as	as	ADP
dti-2185	533	33	langmuir	langmuir	PROPN
dti-2185	533	34	monolayer	monolayer	PROPN
dti-2185	533	35	.	.	PUNCT
dti-2185	534	1	mol	mol	ADP
dti-2185	534	2	membr	membr	NOUN
dti-2185	534	3	biol	biol	PROPN
dti-2185	534	4	.	.	PUNCT
dti-2185	535	1	2015;32(5	2015;32(5	NUM
dti-2185	535	2	-	-	PUNCT
dti-2185	535	3	8):189	8):189	NUM
dti-2185	535	4	-	-	PUNCT
dti-2185	535	5	197	197	NUM
dti-2185	535	6	.	.	PUNCT
dti-2185	535	7	crossref	crossref	PROPN
dti-2185	535	8	medline	medline	NOUN
dti-2185	535	9	73	73	NUM
dti-2185	535	10	.	.	PUNCT
dti-2185	536	1	węder	węder	NOUN
dti-2185	536	2	k	k	PROPN
dti-2185	536	3	,	,	PUNCT
dti-2185	536	4	mach	mach	NOUN
dti-2185	536	5	m	m	PROPN
dti-2185	536	6	,	,	PUNCT
dti-2185	536	7	hąc	hąc	NOUN
dti-2185	536	8	-	-	PUNCT
dti-2185	536	9	wydro	wydro	NOUN
dti-2185	536	10	k	k	NOUN
dti-2185	536	11	,	,	PUNCT
dti-2185	536	12	wydro	wydro	PROPN
dti-2185	536	13	p.	p.	PROPN
dti-2185	536	14	studies	study	NOUN
dti-2185	536	15	on	on	ADP
dti-2185	536	16	the	the	DET
dti-2185	536	17	interactions	interaction	NOUN
dti-2185	536	18	of	of	ADP
dti-2185	536	19	anticancer	anticancer	NOUN
dti-2185	536	20	drug	drug	NOUN
dti-2185	536	21	minerval	minerval	NOUN
dti-2185	536	22	with	with	ADP
dti-2185	536	23	membrane	membrane	NOUN
dti-2185	536	24	lipids	lipid	NOUN
dti-2185	536	25	in	in	ADP
dti-2185	536	26	binary	binary	ADJ
dti-2185	536	27	and	and	CCONJ
dti-2185	536	28	ternary	ternary	ADJ
dti-2185	536	29	langmuir	langmuir	PROPN
dti-2185	536	30	monolayers	monolayer	NOUN
dti-2185	536	31	.	.	PUNCT
dti-2185	537	1	biochim	biochim	PROPN
dti-2185	537	2	biophys	biophy	NOUN
dti-2185	537	3	acta	acta	PROPN
dti-2185	537	4	biomembr	biomembr	NOUN
dti-2185	537	5	.	.	PUNCT
dti-2185	538	1	2018;1860(11):2329	2018;1860(11):2329	X
dti-2185	538	2	-	-	SYM
dti-2185	538	3	2336	2336	NUM
dti-2185	538	4	.	.	PUNCT
dti-2185	539	1	crossref	crossref	PROPN
dti-2185	539	2	medline	medline	NOUN
dti-2185	539	3	74	74	NUM
dti-2185	539	4	.	.	PUNCT
dti-2185	540	1	rebillard	rebillard	VERB
dti-2185	540	2	a	a	DET
dti-2185	540	3	,	,	PUNCT
dti-2185	540	4	lagadic	lagadic	ADJ
dti-2185	540	5	-	-	ADJ
dti-2185	540	6	gossmann	gossmann	ADJ
dti-2185	540	7	d	d	NOUN
dti-2185	540	8	,	,	PUNCT
dti-2185	540	9	dimanche	dimanche	NOUN
dti-2185	540	10	-	-	PUNCT
dti-2185	540	11	boitrel	boitrel	PROPN
dti-2185	540	12	mt	mt	PROPN
dti-2185	540	13	.	.	PROPN
dti-2185	540	14	cisplatin	cisplatin	NOUN
dti-2185	540	15	cytotoxicity	cytotoxicity	NOUN
dti-2185	540	16	:	:	PUNCT
dti-2185	540	17	dna	dna	NOUN
dti-2185	540	18	and	and	CCONJ
dti-2185	540	19	plasma	plasma	NOUN
dti-2185	540	20	membrane	membrane	NOUN
dti-2185	540	21	targets	target	NOUN
dti-2185	540	22	.	.	PUNCT
dti-2185	541	1	curr	curr	PROPN
dti-2185	541	2	med	med	PROPN
dti-2185	541	3	chem	chem	NOUN
dti-2185	541	4	.	.	PUNCT
dti-2185	542	1	2008;15(26):2656	2008;15(26):2656	NUM
dti-2185	542	2	-	-	SYM
dti-2185	542	3	2663	2663	NUM
dti-2185	542	4	.	.	PUNCT
dti-2185	543	1	crossref	crossref	PROPN
dti-2185	543	2	medline	medline	NOUN
dti-2185	543	3	75	75	NUM
dti-2185	543	4	.	.	PUNCT
dti-2185	544	1	lacour	lacour	PROPN
dti-2185	544	2	s	s	PROPN
dti-2185	544	3	,	,	PUNCT
dti-2185	544	4	hammann	hammann	X
dti-2185	544	5	a	a	DET
dti-2185	544	6	,	,	PUNCT
dti-2185	544	7	grazide	grazide	NOUN
dti-2185	544	8	s	s	PROPN
dti-2185	544	9	,	,	PUNCT
dti-2185	544	10	et	et	PROPN
dti-2185	544	11	al	al	PROPN
dti-2185	544	12	.	.	PUNCT
dti-2185	544	13	cisplatin	cisplatin	NOUN
dti-2185	544	14	-	-	PUNCT
dti-2185	544	15	induced	induce	VERB
dti-2185	544	16	cd95	cd95	PROPN
dti-2185	544	17	redistribution	redistribution	NOUN
dti-2185	544	18	into	into	ADP
dti-2185	544	19	membrane	membrane	NOUN
dti-2185	544	20	lipid	lipid	NOUN
dti-2185	544	21	rafts	raft	NOUN
dti-2185	544	22	of	of	ADP
dti-2185	544	23	ht29	ht29	PROPN
dti-2185	544	24	human	human	ADJ
dti-2185	544	25	colon	colon	NOUN
dti-2185	544	26	cancer	cancer	NOUN
dti-2185	544	27	cells	cell	NOUN
dti-2185	544	28	.	.	PUNCT
dti-2185	545	1	cancer	cancer	NOUN
dti-2185	545	2	res	re	NOUN
dti-2185	545	3	.	.	PUNCT
dti-2185	546	1	2004;64(10):3593	2004;64(10):3593	NUM
dti-2185	546	2	-	-	SYM
dti-2185	546	3	3598	3598	NUM
dti-2185	546	4	.	.	PUNCT
dti-2185	547	1	crossref	crossref	PROPN
dti-2185	547	2	medline	medline	NOUN
dti-2185	547	3	76	76	NUM
dti-2185	547	4	.	.	PUNCT
dti-2185	548	1	rebillard	rebillard	VERB
dti-2185	548	2	a	a	DET
dti-2185	548	3	,	,	PUNCT
dti-2185	548	4	tekpli	tekpli	ADJ
dti-2185	548	5	x	x	NOUN
dti-2185	548	6	,	,	PUNCT
dti-2185	548	7	meurette	meurette	PROPN
dti-2185	548	8	o	o	PROPN
dti-2185	548	9	,	,	PUNCT
dti-2185	548	10	et	et	PROPN
dti-2185	548	11	al	al	PROPN
dti-2185	548	12	.	.	PUNCT
dti-2185	549	1	cisplatin	cisplatin	NOUN
dti-2185	549	2	-	-	PUNCT
dti-2185	549	3	induced	induce	VERB
dti-2185	549	4	apoptosis	apoptosis	NOUN
dti-2185	549	5	involves	involve	VERB
dti-2185	549	6	membrane	membrane	NOUN
dti-2185	549	7	fluidification	fluidification	NOUN
dti-2185	549	8	via	via	ADP
dti-2185	549	9	inhibition	inhibition	NOUN
dti-2185	549	10	of	of	ADP
dti-2185	549	11	nhe1	nhe1	PROPN
dti-2185	549	12	in	in	ADP
dti-2185	549	13	human	human	ADJ
dti-2185	549	14	colon	colon	NOUN
dti-2185	549	15	cancer	cancer	NOUN
dti-2185	549	16	cells	cell	NOUN
dti-2185	549	17	.	.	PUNCT
dti-2185	550	1	cancer	cancer	NOUN
dti-2185	550	2	res	re	NOUN
dti-2185	550	3	.	.	PUNCT
dti-2185	551	1	2007;67(16):7865	2007;67(16):7865	NUM
dti-2185	551	2	-	-	SYM
dti-2185	551	3	7874	7874	NUM
dti-2185	551	4	.	.	PUNCT
dti-2185	552	1	crossref	crossref	PROPN
dti-2185	552	2	medline	medline	PROPN
dti-2185	552	3	77	77	NUM
dti-2185	552	4	.	.	PUNCT
dti-2185	553	1	berquand	berquand	PROPN
dti-2185	553	2	a	a	DET
dti-2185	553	3	,	,	PUNCT
dti-2185	553	4	fa	fa	PROPN
dti-2185	553	5	n	n	CCONJ
dti-2185	553	6	,	,	PUNCT
dti-2185	553	7	dufrêne	dufrêne	VERB
dti-2185	553	8	yf	yf	NOUN
dti-2185	553	9	,	,	PUNCT
dti-2185	553	10	mingeot	mingeot	NOUN
dti-2185	553	11	-	-	PUNCT
dti-2185	553	12	leclercq	leclercq	PROPN
dti-2185	553	13	mp	mp	PROPN
dti-2185	553	14	.	.	PROPN
dti-2185	553	15	interaction	interaction	NOUN
dti-2185	553	16	of	of	ADP
dti-2185	553	17	the	the	DET
dti-2185	553	18	macrolide	macrolide	ADJ
dti-2185	553	19	antibiotic	antibiotic	ADJ
dti-2185	553	20	azithromycin	azithromycin	NOUN
dti-2185	553	21	with	with	ADP
dti-2185	553	22	lipid	lipid	ADJ
dti-2185	553	23	bilayers	bilayer	NOUN
dti-2185	553	24	:	:	PUNCT
dti-2185	553	25	effect	effect	NOUN
dti-2185	553	26	on	on	ADP
dti-2185	553	27	membrane	membrane	NOUN
dti-2185	553	28	organization	organization	NOUN
dti-2185	553	29	,	,	PUNCT
dti-2185	553	30	fluidity	fluidity	NOUN
dti-2185	553	31	,	,	PUNCT
dti-2185	553	32	and	and	CCONJ
dti-2185	553	33	permeability	permeability	NOUN
dti-2185	553	34	.	.	PUNCT
dti-2185	554	1	pharm	pharm	NOUN
dti-2185	554	2	res	re	NOUN
dti-2185	554	3	.	.	PUNCT
dti-2185	555	1	2005;22(3):465	2005;22(3):465	NUM
dti-2185	555	2	-	-	SYM
dti-2185	555	3	475	475	NUM
dti-2185	555	4	.	.	PUNCT
dti-2185	556	1	crossref	crossref	PROPN
dti-2185	556	2	medline	medline	PROPN
dti-2185	556	3	78	78	NUM
dti-2185	556	4	.	.	PUNCT
dti-2185	557	1	alves	alves	PROPN
dti-2185	557	2	ac	ac	PROPN
dti-2185	557	3	,	,	PUNCT
dti-2185	557	4	ribeiro	ribeiro	PROPN
dti-2185	557	5	d	d	PROPN
dti-2185	557	6	,	,	PUNCT
dti-2185	557	7	horta	horta	PROPN
dti-2185	557	8	m	m	PROPN
dti-2185	557	9	,	,	PUNCT
dti-2185	557	10	lima	lima	PROPN
dti-2185	557	11	jlfc	jlfc	PROPN
dti-2185	557	12	,	,	PUNCT
dti-2185	557	13	nunes	nunes	PROPN
dti-2185	557	14	c	c	NOUN
dti-2185	557	15	,	,	PUNCT
dti-2185	557	16	reis	reis	NOUN
dti-2185	557	17	s.	s.	PROPN
dti-2185	557	18	a	a	DET
dti-2185	557	19	biophysical	biophysical	ADJ
dti-2185	557	20	approach	approach	NOUN
dti-2185	557	21	to	to	ADP
dti-2185	557	22	daunorubicin	daunorubicin	PROPN
dti-2185	557	23	interaction	interaction	NOUN
dti-2185	557	24	with	with	ADP
dti-2185	557	25	model	model	NOUN
dti-2185	557	26	membranes	membrane	NOUN
dti-2185	557	27	:	:	PUNCT
dti-2185	557	28	relevance	relevance	NOUN
dti-2185	557	29	for	for	ADP
dti-2185	557	30	the	the	DET
dti-2185	557	31	drug	drug	NOUN
dti-2185	557	32	’s	’s	PART
dti-2185	557	33	biological	biological	ADJ
dti-2185	557	34	activity	activity	NOUN
dti-2185	557	35	.	.	PUNCT
dti-2185	558	1	j	j	PROPN
dti-2185	558	2	r	r	NOUN
dti-2185	558	3	soc	soc	NOUN
dti-2185	558	4	interface	interface	NOUN
dti-2185	558	5	.	.	PUNCT
dti-2185	559	1	2017;14(133):20170408	2017;14(133):20170408	X
dti-2185	559	2	.	.	PUNCT
dti-2185	560	1	crossref	crossref	PROPN
dti-2185	560	2	medline	medline	PROPN
dti-2185	560	3	79	79	NUM
dti-2185	560	4	.	.	PUNCT
dti-2185	561	1	alves	alves	PROPN
dti-2185	561	2	ac	ac	PROPN
dti-2185	561	3	,	,	PUNCT
dti-2185	561	4	magarkar	magarkar	PROPN
dti-2185	561	5	a	a	PROPN
dti-2185	561	6	,	,	PUNCT
dti-2185	561	7	horta	horta	PROPN
dti-2185	561	8	m	m	PROPN
dti-2185	561	9	,	,	PUNCT
dti-2185	561	10	et	et	PROPN
dti-2185	561	11	al	al	PROPN
dti-2185	561	12	.	.	PUNCT
dti-2185	561	13	influence	influence	NOUN
dti-2185	561	14	of	of	ADP
dti-2185	561	15	doxorubicin	doxorubicin	PROPN
dti-2185	561	16	on	on	ADP
dti-2185	561	17	model	model	NOUN
dti-2185	561	18	cell	cell	NOUN
dti-2185	561	19	membrane	membrane	NOUN
dti-2185	561	20	properties	property	NOUN
dti-2185	561	21	:	:	PUNCT
dti-2185	561	22	insights	insight	NOUN
dti-2185	561	23	from	from	ADP
dti-2185	561	24	in	in	ADP
dti-2185	561	25	vitro	vitro	X
dti-2185	561	26	and	and	CCONJ
dti-2185	561	27	in	in	ADP
dti-2185	561	28	silico	silico	NOUN
dti-2185	561	29	studies	study	NOUN
dti-2185	561	30	.	.	PUNCT
dti-2185	562	1	sci	sci	PROPN
dti-2185	562	2	rep	rep	PROPN
dti-2185	562	3	.	.	PROPN
dti-2185	562	4	2017;7(1):6343	2017;7(1):6343	PROPN
dti-2185	562	5	.	.	PUNCT
dti-2185	563	1	crossref	crossref	PROPN
dti-2185	563	2	medline	medline	PROPN
dti-2185	563	3	https://doi.org/10.1039/c5md00108k	https://doi.org/10.1039/c5md00108k	PROPN
dti-2185	563	4	https://doi.org/10.3390/membranes7030033	https://doi.org/10.3390/membranes7030033	PROPN
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dti-2185	563	7	https://www.ncbi.nlm.nih.gov/pubmed/31207252	https://www.ncbi.nlm.nih.gov/pubmed/31207252	NUM
dti-2185	563	8	https://doi.org/10.1097/00000539-200101000-00008	https://doi.org/10.1097/00000539-200101000-00008	NOUN
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dti-2185	563	10	https://doi.org/10.1007/s00540-010-0943-0	https://doi.org/10.1007/s00540-010-0943-0	NUM
dti-2185	563	11	https://www.ncbi.nlm.nih.gov/pubmed/20414686	https://www.ncbi.nlm.nih.gov/pubmed/20414686	NUM
dti-2185	563	12	https://doi.org/10.1213/ane.0b013e31823ed410	https://doi.org/10.1213/ane.0b013e31823ed410	NUM
dti-2185	563	13	https://www.ncbi.nlm.nih.gov/pubmed/22156330	https://www.ncbi.nlm.nih.gov/pubmed/22156330	NUM
dti-2185	563	14	https://doi.org/10.1074/jbc.m800778200	https://doi.org/10.1074/jbc.m800778200	X
dti-2185	563	15	https://www.ncbi.nlm.nih.gov/pubmed/18566454	https://www.ncbi.nlm.nih.gov/pubmed/18566454	NUM
dti-2185	563	16	https://doi.org/10.1097/eja.0b013e32833bf5e4	https://doi.org/10.1097/eja.0b013e32833bf5e4	PROPN
dti-2185	563	17	https://www.ncbi.nlm.nih.gov/pubmed/20601889	https://www.ncbi.nlm.nih.gov/pubmed/20601889	PROPN
dti-2185	564	1	https://doi.org/10.3389/fphar.2013.00150	https://doi.org/10.3389/fphar.2013.00150	PROPN
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dti-2185	564	3	https://doi.org/10.1080/080370501753400665	https://doi.org/10.1080/080370501753400665	NOUN
dti-2185	564	4	https://www.ncbi.nlm.nih.gov/pubmed/11822540	https://www.ncbi.nlm.nih.gov/pubmed/11822540	NUM
dti-2185	564	5	https://doi.org/10.1097/mnh.0b013e328040bfbd	https://doi.org/10.1097/mnh.0b013e328040bfbd	PRON
dti-2185	564	6	https://www.ncbi.nlm.nih.gov/pubmed/17293683	https://www.ncbi.nlm.nih.gov/pubmed/17293683	NUM
dti-2185	565	1	https://doi.org/10.9734/jammr/2019/v29i1130142	https://doi.org/10.9734/jammr/2019/v29i1130142	ADP
dti-2185	565	2	https://doi.org/10.1074/jbc.m705795200	https://doi.org/10.1074/jbc.m705795200	X
dti-2185	565	3	https://www.ncbi.nlm.nih.gov/pubmed/18048357	https://www.ncbi.nlm.nih.gov/pubmed/18048357	NUM
dti-2185	565	4	https://doi.org/10.1016/j.brainres.2007.09.096	https://doi.org/10.1016/j.brainres.2007.09.096	NOUN
dti-2185	565	5	https://www.ncbi.nlm.nih.gov/pubmed/17980352	https://www.ncbi.nlm.nih.gov/pubmed/17980352	X
dti-2185	565	6	https://doi.org/10.1016/0006-2952(82)90543-3	https://doi.org/10.1016/0006-2952(82)90543-3	PROPN
dti-2185	565	7	https://www.ncbi.nlm.nih.gov/pubmed/6889866	https://www.ncbi.nlm.nih.gov/pubmed/6889866	X
dti-2185	566	1	https://doi.org/10.1016/s0378-5173(02)00560-4	https://doi.org/10.1016/s0378-5173(02)00560-4	PROPN
dti-2185	566	2	https://doi.org/10.1073/pnas.0802253105	https://doi.org/10.1073/pnas.0802253105	NOUN
dti-2185	566	3	https://www.ncbi.nlm.nih.gov/pubmed/18599439	https://www.ncbi.nlm.nih.gov/pubmed/18599439	PRON
dti-2185	566	4	https://doi.org/10.1074/jbc.m105946200	https://doi.org/10.1074/jbc.m105946200	X
dti-2185	566	5	https://www.ncbi.nlm.nih.gov/pubmed/11432874	https://www.ncbi.nlm.nih.gov/pubmed/11432874	PUNCT
dti-2185	566	6	https://doi.org/10.1016/j.bbamem.2014.11.023	https://doi.org/10.1016/j.bbamem.2014.11.023	PROPN
dti-2185	566	7	https://www.ncbi.nlm.nih.gov/pubmed/25475646	https://www.ncbi.nlm.nih.gov/pubmed/25475646	NOUN
dti-2185	566	8	https://doi.org/10.1098/rsos.171710	https://doi.org/10.1098/rsos.171710	NOUN
dti-2185	566	9	https://www.ncbi.nlm.nih.gov/pubmed/29515878	https://www.ncbi.nlm.nih.gov/pubmed/29515878	PROPN
dti-2185	566	10	https://doi.org/10.1074/jbc.m112.348490	https://doi.org/10.1074/jbc.m112.348490	PROPN
dti-2185	566	11	https://www.ncbi.nlm.nih.gov/pubmed/22433858	https://www.ncbi.nlm.nih.gov/pubmed/22433858	X
dti-2185	566	12	https://doi.org/10.2174/0929867325666180111100601	https://doi.org/10.2174/0929867325666180111100601	PRON
dti-2185	566	13	https://www.ncbi.nlm.nih.gov/pubmed/29332565	https://www.ncbi.nlm.nih.gov/pubmed/29332565	PROPN
dti-2185	566	14	https://doi.org/10.1158/1535-7163.mct-07-0202	https://doi.org/10.1158/1535-7163.mct-07-0202	X
dti-2185	566	15	https://www.ncbi.nlm.nih.gov/pubmed/17699729	https://www.ncbi.nlm.nih.gov/pubmed/17699729	NUM
dti-2185	566	16	https://doi.org/10.1016/j.bbamem.2016.06.025	https://doi.org/10.1016/j.bbamem.2016.06.025	NUM
dti-2185	566	17	https://www.ncbi.nlm.nih.gov/pubmed/27368477	https://www.ncbi.nlm.nih.gov/pubmed/27368477	NUM
dti-2185	566	18	https://doi.org/10.1021/jp802165n	https://doi.org/10.1021/jp802165n	PROPN
dti-2185	566	19	https://www.ncbi.nlm.nih.gov/pubmed/18712919	https://www.ncbi.nlm.nih.gov/pubmed/18712919	NUM
dti-2185	566	20	https://doi.org/10.1016/j.bbamem.2013.01.017	https://doi.org/10.1016/j.bbamem.2013.01.017	NUM
dti-2185	566	21	https://www.ncbi.nlm.nih.gov/pubmed/23376656	https://www.ncbi.nlm.nih.gov/pubmed/23376656	NUM
dti-2185	566	22	https://doi.org/10.1021/jp401407d	https://doi.org/10.1021/jp401407d	NOUN
dti-2185	566	23	https://www.ncbi.nlm.nih.gov/pubmed/23738749	https://www.ncbi.nlm.nih.gov/pubmed/23738749	NUM
dti-2185	567	1	https://doi.org/10.3109/09687688.2015.1125537	https://doi.org/10.3109/09687688.2015.1125537	INTJ
dti-2185	567	2	https://www.ncbi.nlm.nih.gov/pubmed/26911703	https://www.ncbi.nlm.nih.gov/pubmed/26911703	PROPN
dti-2185	568	1	https://doi.org/10.1016/j.bbamem.2018.05.019	https://doi.org/10.1016/j.bbamem.2018.05.019	NUM
dti-2185	568	2	https://www.ncbi.nlm.nih.gov/pubmed/29864405	https://www.ncbi.nlm.nih.gov/pubmed/29864405	X
dti-2185	568	3	https://doi.org/10.2174/092986708786242903	https://doi.org/10.2174/092986708786242903	NOUN
dti-2185	569	1	https://www.ncbi.nlm.nih.gov/pubmed/18991628	https://www.ncbi.nlm.nih.gov/pubmed/18991628	X
dti-2185	569	2	https://doi.org/10.1158/0008-5472.can-03-2787	https://doi.org/10.1158/0008-5472.can-03-2787	PUNCT
dti-2185	570	1	https://www.ncbi.nlm.nih.gov/pubmed/15150117	https://www.ncbi.nlm.nih.gov/pubmed/15150117	X
dti-2185	570	2	https://doi.org/10.1158/0008-5472.can-07-0353	https://doi.org/10.1158/0008-5472.can-07-0353	PROPN
dti-2185	570	3	https://www.ncbi.nlm.nih.gov/pubmed/17699793	https://www.ncbi.nlm.nih.gov/pubmed/17699793	NUM
dti-2185	570	4	https://doi.org/10.1007/s11095-004-1885-8	https://doi.org/10.1007/s11095-004-1885-8	NUM
dti-2185	570	5	https://www.ncbi.nlm.nih.gov/pubmed/15835753	https://www.ncbi.nlm.nih.gov/pubmed/15835753	NUM
dti-2185	570	6	https://doi.org/10.1098/rsif.2017.0408	https://doi.org/10.1098/rsif.2017.0408	X
dti-2185	570	7	https://www.ncbi.nlm.nih.gov/pubmed/28855387	https://www.ncbi.nlm.nih.gov/pubmed/28855387	VERB
dti-2185	570	8	https://doi.org/10.1038/s41598-017-06445-z	https://doi.org/10.1038/s41598-017-06445-z	PROPN
dti-2185	570	9	https://www.ncbi.nlm.nih.gov/pubmed/28740256	https://www.ncbi.nlm.nih.gov/pubmed/28740256	X
dti-2185	570	10	tsuchiya	tsuchiya	PROPN
dti-2185	570	11	and	and	CCONJ
dti-2185	570	12	mizogami	mizogami	PROPN
dti-2185	570	13	47	47	NUM
dti-2185	570	14	©	©	PROPN
dti-2185	570	15	2020	2020	NUM
dti-2185	570	16	the	the	DET
dti-2185	570	17	authors	author	NOUN
dti-2185	570	18	.	.	PUNCT
dti-2185	571	1	published	publish	VERB
dti-2185	571	2	by	by	ADP
dti-2185	571	3	aboutscience	aboutscience	NOUN
dti-2185	571	4	80	80	NUM
dti-2185	571	5	.	.	PUNCT
dti-2185	572	1	tsuchiya	tsuchiya	PROPN
dti-2185	572	2	h.	h.	PROPN
dti-2185	572	3	membrane	membrane	NOUN
dti-2185	572	4	interactions	interaction	NOUN
dti-2185	572	5	of	of	ADP
dti-2185	572	6	phytochemicals	phytochemical	NOUN
dti-2185	572	7	as	as	ADP
dti-2185	572	8	their	their	PRON
dti-2185	572	9	molecular	molecular	ADJ
dti-2185	572	10	mechanism	mechanism	NOUN
dti-2185	572	11	applicable	applicable	ADJ
dti-2185	572	12	to	to	ADP
dti-2185	572	13	the	the	DET
dti-2185	572	14	discovery	discovery	NOUN
dti-2185	572	15	of	of	ADP
dti-2185	572	16	drug	drug	NOUN
dti-2185	572	17	leads	lead	VERB
dti-2185	572	18	from	from	ADP
dti-2185	572	19	plants	plant	NOUN
dti-2185	572	20	.	.	PUNCT
dti-2185	573	1	molecules	molecule	NOUN
dti-2185	573	2	.	.	PUNCT
dti-2185	574	1	2015;20(10):18923	2015;20(10):18923	NUM
dti-2185	574	2	-	-	SYM
dti-2185	574	3	18966	18966	NUM
dti-2185	574	4	.	.	PUNCT
dti-2185	575	1	crossref	crossref	PROPN
dti-2185	575	2	medline	medline	NOUN
dti-2185	575	3	81	81	NUM
dti-2185	575	4	.	.	PUNCT
dti-2185	576	1	tarahovsky	tarahovsky	PROPN
dti-2185	576	2	ys	ys	PROPN
dti-2185	576	3	,	,	PUNCT
dti-2185	576	4	kim	kim	PROPN
dti-2185	576	5	ya	ya	PROPN
dti-2185	576	6	,	,	PUNCT
dti-2185	576	7	yagolnik	yagolnik	X
dti-2185	576	8	ea	ea	PROPN
dti-2185	576	9	,	,	PUNCT
dti-2185	576	10	muzafarov	muzafarov	PROPN
dti-2185	576	11	en	en	PROPN
dti-2185	576	12	.	.	PUNCT
dti-2185	576	13	flavonoidmembrane	flavonoidmembrane	NOUN
dti-2185	576	14	interactions	interaction	NOUN
dti-2185	576	15	:	:	PUNCT
dti-2185	576	16	involvement	involvement	NOUN
dti-2185	576	17	of	of	ADP
dti-2185	576	18	flavonoid	flavonoid	NOUN
dti-2185	576	19	-	-	PUNCT
dti-2185	576	20	metal	metal	NOUN
dti-2185	576	21	complexes	complex	NOUN
dti-2185	576	22	in	in	ADP
dti-2185	576	23	raft	raft	NOUN
dti-2185	576	24	signaling	signal	VERB
dti-2185	576	25	.	.	PUNCT
dti-2185	577	1	biochim	biochim	PROPN
dti-2185	577	2	biophys	biophy	NOUN
dti-2185	577	3	acta	acta	PROPN
dti-2185	577	4	.	.	PUNCT
dti-2185	578	1	2014;1838(5):12351246	2014;1838(5):12351246	NUM
dti-2185	578	2	.	.	PUNCT
dti-2185	579	1	crossref	crossref	PROPN
dti-2185	579	2	medline	medline	PROPN
dti-2185	579	3	82	82	NUM
dti-2185	579	4	.	.	PUNCT
dti-2185	580	1	selvaraj	selvaraj	PROPN
dti-2185	580	2	s	s	PROPN
dti-2185	580	3	,	,	PUNCT
dti-2185	580	4	krishnaswamy	krishnaswamy	PROPN
dti-2185	580	5	s	s	PROPN
dti-2185	580	6	,	,	PUNCT
dti-2185	580	7	devashya	devashya	ADJ
dti-2185	580	8	v	v	ADP
dti-2185	580	9	,	,	PUNCT
dti-2185	580	10	sethuraman	sethuraman	PROPN
dti-2185	580	11	s	s	PROPN
dti-2185	580	12	,	,	PUNCT
dti-2185	580	13	krishnan	krishnan	PROPN
dti-2185	580	14	um	um	INTJ
dti-2185	580	15	.	.	PUNCT
dti-2185	580	16	influence	influence	NOUN
dti-2185	580	17	of	of	ADP
dti-2185	580	18	membrane	membrane	NOUN
dti-2185	580	19	lipid	lipid	NOUN
dti-2185	580	20	composition	composition	NOUN
dti-2185	580	21	on	on	ADP
dti-2185	580	22	flavonoidmembrane	flavonoidmembrane	NOUN
dti-2185	580	23	interactions	interaction	NOUN
dti-2185	580	24	:	:	PUNCT
dti-2185	580	25	implications	implication	NOUN
dti-2185	580	26	on	on	ADP
dti-2185	580	27	their	their	PRON
dti-2185	580	28	biological	biological	ADJ
dti-2185	580	29	activity	activity	NOUN
dti-2185	580	30	.	.	PUNCT
dti-2185	581	1	prog	prog	NOUN
dti-2185	581	2	lipid	lipid	NOUN
dti-2185	581	3	res	re	NOUN
dti-2185	581	4	.	.	PUNCT
dti-2185	582	1	2015;58:1	2015;58:1	NUM
dti-2185	582	2	-	-	SYM
dti-2185	582	3	13	13	NUM
dti-2185	582	4	.	.	PUNCT
dti-2185	583	1	crossref	crossref	PROPN
dti-2185	583	2	medline	medline	PROPN
dti-2185	583	3	83	83	NUM
dti-2185	583	4	.	.	PUNCT
dti-2185	584	1	tarahovsky	tarahovsky	PROPN
dti-2185	584	2	ys	ys	NOUN
dti-2185	584	3	,	,	PUNCT
dti-2185	584	4	muzafarov	muzafarov	X
dti-2185	584	5	en	en	PROPN
dti-2185	584	6	,	,	PUNCT
dti-2185	584	7	kim	kim	PROPN
dti-2185	584	8	ya	ya	PROPN
dti-2185	584	9	.	.	PROPN
dti-2185	585	1	rafts	raft	NOUN
dti-2185	585	2	making	make	VERB
dti-2185	585	3	and	and	CCONJ
dti-2185	585	4	rafts	raft	NOUN
dti-2185	585	5	braking	brake	VERB
dti-2185	585	6	:	:	PUNCT
dti-2185	585	7	how	how	SCONJ
dti-2185	585	8	plant	plant	NOUN
dti-2185	585	9	flavonoids	flavonoid	NOUN
dti-2185	585	10	may	may	AUX
dti-2185	585	11	control	control	VERB
dti-2185	585	12	membrane	membrane	NOUN
dti-2185	585	13	heterogeneity	heterogeneity	NOUN
dti-2185	585	14	.	.	PUNCT
dti-2185	586	1	mol	mol	ADP
dti-2185	586	2	cell	cell	NOUN
dti-2185	586	3	biochem	biochem	PROPN
dti-2185	586	4	.	.	PUNCT
dti-2185	587	1	2008;314(1	2008;314(1	NOUN
dti-2185	587	2	-	-	PUNCT
dti-2185	587	3	2):65	2):65	NUM
dti-2185	587	4	-	-	SYM
dti-2185	587	5	71	71	NUM
dti-2185	587	6	.	.	PUNCT
dti-2185	588	1	crossref	crossref	PROPN
dti-2185	588	2	medline	medline	PROPN
dti-2185	588	3	84	84	NUM
dti-2185	588	4	.	.	PUNCT
dti-2185	589	1	tsuchiya	tsuchiya	PROPN
dti-2185	589	2	h	h	PROPN
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dti-2185	589	4	mizogami	mizogami	PROPN
dti-2185	589	5	m.	m.	NOUN
dti-2185	589	6	plant	plant	NOUN
dti-2185	589	7	components	component	NOUN
dti-2185	589	8	exhibit	exhibit	VERB
dti-2185	589	9	pharmacological	pharmacological	ADJ
dti-2185	589	10	activities	activity	NOUN
dti-2185	589	11	and	and	CCONJ
dti-2185	589	12	drug	drug	NOUN
dti-2185	589	13	interactions	interaction	NOUN
dti-2185	589	14	by	by	ADP
dti-2185	589	15	acting	act	VERB
dti-2185	589	16	on	on	ADP
dti-2185	589	17	lipid	lipid	ADJ
dti-2185	589	18	membranes	membrane	NOUN
dti-2185	589	19	.	.	PUNCT
dti-2185	590	1	pharmacog	pharmacog	PROPN
dti-2185	590	2	commun	commun	PROPN
dti-2185	590	3	.	.	PUNCT
dti-2185	591	1	2012;2:58–71	2012;2:58–71	X
dti-2185	591	2	.	.	PUNCT
dti-2185	592	1	online	online	ADJ
dti-2185	592	2	85	85	NUM
dti-2185	592	3	.	.	PUNCT
dti-2185	592	4	psahoulia	psahoulia	PROPN
dti-2185	592	5	fh	fh	PROPN
dti-2185	592	6	,	,	PUNCT
dti-2185	592	7	drosopoulos	drosopoulos	NOUN
dti-2185	592	8	kg	kg	PROPN
dti-2185	592	9	,	,	PUNCT
dti-2185	592	10	doubravska	doubravska	PROPN
dti-2185	592	11	l	l	NOUN
dti-2185	592	12	,	,	PUNCT
dti-2185	592	13	andera	andera	NOUN
dti-2185	592	14	l	l	NOUN
dti-2185	592	15	,	,	PUNCT
dti-2185	592	16	pintzas	pintzas	PROPN
dti-2185	592	17	a.	a.	NOUN
dti-2185	592	18	quercetin	quercetin	NOUN
dti-2185	592	19	enhances	enhance	VERB
dti-2185	592	20	trail	trail	NOUN
dti-2185	592	21	-	-	PUNCT
dti-2185	592	22	mediated	mediate	VERB
dti-2185	592	23	apoptosis	apoptosis	NOUN
dti-2185	592	24	in	in	ADP
dti-2185	592	25	colon	colon	NOUN
dti-2185	592	26	cancer	cancer	NOUN
dti-2185	592	27	cells	cell	NOUN
dti-2185	592	28	by	by	ADP
dti-2185	592	29	inducing	induce	VERB
dti-2185	592	30	the	the	DET
dti-2185	592	31	accumulation	accumulation	NOUN
dti-2185	592	32	of	of	ADP
dti-2185	592	33	death	death	NOUN
dti-2185	592	34	receptors	receptor	NOUN
dti-2185	592	35	in	in	ADP
dti-2185	592	36	lipid	lipid	ADJ
dti-2185	592	37	rafts	raft	NOUN
dti-2185	592	38	.	.	PUNCT
dti-2185	593	1	mol	mol	ADP
dti-2185	593	2	cancer	cancer	NOUN
dti-2185	593	3	ther	ther	ADV
dti-2185	593	4	.	.	PUNCT
dti-2185	594	1	2007;6(9):2591	2007;6(9):2591	NUM
dti-2185	594	2	-	-	PUNCT
dti-2185	594	3	2599	2599	NUM
dti-2185	594	4	.	.	PUNCT
dti-2185	595	1	crossref	crossref	PROPN
dti-2185	595	2	medline	medline	PROPN
dti-2185	595	3	86	86	NUM
dti-2185	595	4	.	.	PUNCT
dti-2185	596	1	kaneko	kaneko	PROPN
dti-2185	596	2	m	m	PROPN
dti-2185	596	3	,	,	PUNCT
dti-2185	596	4	takimoto	takimoto	PROPN
dti-2185	596	5	h	h	PROPN
dti-2185	596	6	,	,	PUNCT
dti-2185	596	7	sugiyama	sugiyama	PROPN
dti-2185	596	8	t	t	PROPN
dti-2185	596	9	,	,	PUNCT
dti-2185	596	10	seki	seki	PROPN
dti-2185	596	11	y	y	PROPN
dti-2185	596	12	,	,	PUNCT
dti-2185	596	13	kawaguchi	kawaguchi	PROPN
dti-2185	596	14	k	k	PROPN
dti-2185	596	15	,	,	PUNCT
dti-2185	596	16	kumazawa	kumazawa	PROPN
dti-2185	596	17	y.	y.	PROPN
dti-2185	596	18	suppressive	suppressive	ADJ
dti-2185	596	19	effects	effect	NOUN
dti-2185	596	20	of	of	ADP
dti-2185	596	21	the	the	DET
dti-2185	596	22	flavonoids	flavonoid	NOUN
dti-2185	596	23	quercetin	quercetin	NOUN
dti-2185	596	24	and	and	CCONJ
dti-2185	596	25	luteolin	luteolin	PROPN
dti-2185	596	26	on	on	ADP
dti-2185	596	27	the	the	DET
dti-2185	596	28	accumulation	accumulation	NOUN
dti-2185	596	29	of	of	ADP
dti-2185	596	30	lipid	lipid	ADJ
dti-2185	596	31	rafts	raft	NOUN
dti-2185	596	32	after	after	ADP
dti-2185	596	33	signal	signal	NOUN
dti-2185	596	34	transduction	transduction	NOUN
dti-2185	596	35	via	via	ADP
dti-2185	596	36	receptors	receptor	NOUN
dti-2185	596	37	.	.	PUNCT
dti-2185	597	1	immunopharmacol	immunopharmacol	PROPN
dti-2185	597	2	immunotoxicol	immunotoxicol	PROPN
dti-2185	597	3	.	.	PUNCT
dti-2185	598	1	2008;30(4):867	2008;30(4):867	NUM
dti-2185	598	2	-	-	PUNCT
dti-2185	598	3	882	882	NUM
dti-2185	598	4	.	.	PUNCT
dti-2185	599	1	crossref	crossref	PROPN
dti-2185	599	2	medline	medline	NOUN
dti-2185	599	3	87	87	NUM
dti-2185	599	4	.	.	PUNCT
dti-2185	600	1	ionescu	ionescu	PROPN
dti-2185	600	2	d	d	PROPN
dti-2185	600	3	,	,	PUNCT
dti-2185	600	4	margină	margină	NOUN
dti-2185	600	5	d	d	NOUN
dti-2185	600	6	,	,	PUNCT
dti-2185	600	7	ilie	ilie	PROPN
dti-2185	600	8	m	m	PROPN
dti-2185	600	9	,	,	PUNCT
dti-2185	600	10	iftime	iftime	ADV
dti-2185	600	11	a	a	PRON
dti-2185	600	12	,	,	PUNCT
dti-2185	600	13	ganea	ganea	NOUN
dti-2185	600	14	c.	c.	NOUN
dti-2185	600	15	quercetin	quercetin	NOUN
dti-2185	600	16	and	and	CCONJ
dti-2185	600	17	epigallocatechin-3	epigallocatechin-3	PROPN
dti-2185	600	18	-	-	ADJ
dti-2185	600	19	gallate	gallate	NOUN
dti-2185	600	20	effect	effect	NOUN
dti-2185	600	21	on	on	ADP
dti-2185	600	22	the	the	DET
dti-2185	600	23	anisotropy	anisotropy	NOUN
dti-2185	600	24	of	of	ADP
dti-2185	600	25	model	model	NOUN
dti-2185	600	26	membranes	membrane	NOUN
dti-2185	600	27	with	with	ADP
dti-2185	600	28	cholesterol	cholesterol	NOUN
dti-2185	600	29	.	.	PUNCT
dti-2185	601	1	food	food	NOUN
dti-2185	601	2	chem	chem	NOUN
dti-2185	601	3	toxicol	toxicol	NOUN
dti-2185	601	4	.	.	PUNCT
dti-2185	602	1	2013;61:94100	2013;61:94100	X
dti-2185	602	2	.	.	PUNCT
dti-2185	602	3	crossref	crossref	PROPN
dti-2185	602	4	medline	medline	PROPN
dti-2185	602	5	88	88	NUM
dti-2185	602	6	.	.	PUNCT
dti-2185	603	1	tsuchiya	tsuchiya	PROPN
dti-2185	603	2	h.	h.	PROPN
dti-2185	603	3	stereospecificity	stereospecificity	NOUN
dti-2185	603	4	in	in	ADP
dti-2185	603	5	membrane	membrane	NOUN
dti-2185	603	6	effects	effect	NOUN
dti-2185	603	7	of	of	ADP
dti-2185	603	8	catechins	catechin	NOUN
dti-2185	603	9	.	.	PUNCT
dti-2185	604	1	chem	chem	NOUN
dti-2185	604	2	biol	biol	PROPN
dti-2185	604	3	interact	interact	VERB
dti-2185	604	4	.	.	PUNCT
dti-2185	605	1	2001;134(1):41	2001;134(1):41	NUM
dti-2185	605	2	-	-	SYM
dti-2185	605	3	54	54	NUM
dti-2185	605	4	.	.	PUNCT
dti-2185	606	1	crossref	crossref	PROPN
dti-2185	606	2	medline	medline	PROPN
dti-2185	606	3	89	89	NUM
dti-2185	606	4	.	.	PUNCT
dti-2185	607	1	adachi	adachi	PROPN
dti-2185	607	2	s	s	PROPN
dti-2185	607	3	,	,	PUNCT
dti-2185	607	4	nagao	nagao	ADJ
dti-2185	607	5	t	t	PROPN
dti-2185	607	6	,	,	PUNCT
dti-2185	607	7	ingolfsson	ingolfsson	NOUN
dti-2185	607	8	hi	hi	PROPN
dti-2185	607	9	,	,	PUNCT
dti-2185	607	10	et	et	PROPN
dti-2185	607	11	al	al	PROPN
dti-2185	607	12	.	.	PUNCT
dti-2185	608	1	the	the	DET
dti-2185	608	2	inhibitory	inhibitory	ADJ
dti-2185	608	3	effect	effect	NOUN
dti-2185	608	4	of	of	ADP
dti-2185	608	5	(	(	PUNCT
dti-2185	608	6	-)-epigallocatechin	-)-epigallocatechin	PROPN
dti-2185	608	7	gallate	gallate	NOUN
dti-2185	608	8	on	on	ADP
dti-2185	608	9	activation	activation	NOUN
dti-2185	608	10	of	of	ADP
dti-2185	608	11	the	the	DET
dti-2185	608	12	epidermal	epidermal	ADJ
dti-2185	608	13	growth	growth	NOUN
dti-2185	608	14	factor	factor	NOUN
dti-2185	608	15	receptor	receptor	NOUN
dti-2185	608	16	is	be	AUX
dti-2185	608	17	associated	associate	VERB
dti-2185	608	18	with	with	ADP
dti-2185	608	19	altered	altered	ADJ
dti-2185	608	20	lipid	lipid	NOUN
dti-2185	608	21	order	order	NOUN
dti-2185	608	22	in	in	ADP
dti-2185	608	23	ht29	ht29	PROPN
dti-2185	608	24	colon	colon	NOUN
dti-2185	608	25	cancer	cancer	NOUN
dti-2185	608	26	cells	cell	NOUN
dti-2185	608	27	.	.	PUNCT
dti-2185	609	1	cancer	cancer	NOUN
dti-2185	609	2	res	re	NOUN
dti-2185	609	3	.	.	PUNCT
dti-2185	610	1	2007;67(13):6493	2007;67(13):6493	NUM
dti-2185	610	2	-	-	PUNCT
dti-2185	610	3	6501	6501	NUM
dti-2185	610	4	.	.	PUNCT
dti-2185	611	1	crossref	crossref	PROPN
dti-2185	611	2	medline	medline	NOUN
dti-2185	611	3	90	90	NUM
dti-2185	611	4	.	.	PUNCT
dti-2185	612	1	duhon	duhon	PROPN
dti-2185	612	2	d	d	PROPN
dti-2185	612	3	,	,	PUNCT
dti-2185	612	4	bigelow	bigelow	PROPN
dti-2185	612	5	rl	rl	PROPN
dti-2185	612	6	,	,	PUNCT
dti-2185	612	7	coleman	coleman	PROPN
dti-2185	612	8	dt	dt	PROPN
dti-2185	612	9	,	,	PUNCT
dti-2185	612	10	et	et	PROPN
dti-2185	612	11	al	al	PROPN
dti-2185	612	12	.	.	PUNCT
dti-2185	613	1	the	the	DET
dti-2185	613	2	polyphenol	polyphenol	NOUN
dti-2185	613	3	epigallocatechin-3	epigallocatechin-3	PROPN
dti-2185	613	4	-	-	ADJ
dti-2185	613	5	gallate	gallate	NOUN
dti-2185	613	6	affects	affect	VERB
dti-2185	613	7	lipid	lipid	NOUN
dti-2185	613	8	rafts	raft	NOUN
dti-2185	613	9	to	to	PART
dti-2185	613	10	block	block	VERB
dti-2185	613	11	activation	activation	NOUN
dti-2185	613	12	of	of	ADP
dti-2185	613	13	the	the	DET
dti-2185	613	14	c	c	NOUN
dti-2185	613	15	-	-	PUNCT
dti-2185	613	16	met	meet	VERB
dti-2185	613	17	receptor	receptor	NOUN
dti-2185	613	18	in	in	ADP
dti-2185	613	19	prostate	prostate	NOUN
dti-2185	613	20	cancer	cancer	NOUN
dti-2185	613	21	cells	cell	NOUN
dti-2185	613	22	.	.	PUNCT
dti-2185	614	1	mol	mol	ADP
dti-2185	614	2	carcinog	carcinog	NOUN
dti-2185	614	3	.	.	PUNCT
dti-2185	615	1	2010;49(8):739	2010;49(8):739	NUM
dti-2185	615	2	-	-	SYM
dti-2185	615	3	749	749	NUM
dti-2185	615	4	.	.	PUNCT
dti-2185	616	1	crossref	crossref	PROPN
dti-2185	616	2	medline	medline	PROPN
dti-2185	616	3	91	91	NUM
dti-2185	616	4	.	.	PUNCT
dti-2185	617	1	tsukamoto	tsukamoto	PROPN
dti-2185	617	2	s	s	PROPN
dti-2185	617	3	,	,	PUNCT
dti-2185	617	4	hirotsu	hirotsu	NOUN
dti-2185	617	5	k	k	NOUN
dti-2185	617	6	,	,	PUNCT
dti-2185	617	7	kumazoe	kumazoe	PROPN
dti-2185	617	8	m	m	PROPN
dti-2185	617	9	,	,	PUNCT
dti-2185	617	10	et	et	PROPN
dti-2185	617	11	al	al	PROPN
dti-2185	617	12	.	.	PROPN
dti-2185	618	1	green	green	ADJ
dti-2185	618	2	tea	tea	NOUN
dti-2185	618	3	polyphenol	polyphenol	NOUN
dti-2185	618	4	egcg	egcg	NOUN
dti-2185	618	5	induces	induce	VERB
dti-2185	618	6	lipid	lipid	NOUN
dti-2185	618	7	-	-	PUNCT
dti-2185	618	8	raft	raft	NOUN
dti-2185	618	9	clustering	clustering	NOUN
dti-2185	618	10	and	and	CCONJ
dti-2185	618	11	apoptotic	apoptotic	ADJ
dti-2185	618	12	cell	cell	NOUN
dti-2185	618	13	death	death	NOUN
dti-2185	618	14	by	by	ADP
dti-2185	618	15	activating	activate	VERB
dti-2185	618	16	protein	protein	NOUN
dti-2185	618	17	kinase	kinase	NOUN
dti-2185	618	18	cδ	cδ	NOUN
dti-2185	618	19	and	and	CCONJ
dti-2185	618	20	acid	acid	PROPN
dti-2185	618	21	sphingomyelinase	sphingomyelinase	NOUN
dti-2185	618	22	through	through	ADP
dti-2185	618	23	a	a	DET
dti-2185	618	24	67	67	NUM
dti-2185	618	25	kda	kda	NOUN
dti-2185	618	26	laminin	laminin	NOUN
dti-2185	618	27	receptor	receptor	NOUN
dti-2185	618	28	in	in	ADP
dti-2185	618	29	multiple	multiple	ADJ
dti-2185	618	30	myeloma	myeloma	NOUN
dti-2185	618	31	cells	cell	NOUN
dti-2185	618	32	.	.	PUNCT
dti-2185	619	1	biochem	biochem	PROPN
dti-2185	619	2	j.	j.	PROPN
dti-2185	619	3	2012;443(2):525	2012;443(2):525	PROPN
dti-2185	619	4	-	-	SYM
dti-2185	619	5	534	534	NUM
dti-2185	619	6	.	.	PUNCT
dti-2185	620	1	crossref	crossref	PROPN
dti-2185	620	2	medline	medline	PROPN
dti-2185	620	3	92	92	NUM
dti-2185	620	4	.	.	PUNCT
dti-2185	620	5	verstraeten	verstraeten	VERB
dti-2185	620	6	sv	sv	ADP
dti-2185	620	7	,	,	PUNCT
dti-2185	620	8	oteiza	oteiza	PROPN
dti-2185	620	9	pi	pi	NOUN
dti-2185	620	10	,	,	PUNCT
dti-2185	620	11	fraga	fraga	PROPN
dti-2185	620	12	cg	cg	PROPN
dti-2185	620	13	.	.	PUNCT
dti-2185	621	1	membrane	membrane	NOUN
dti-2185	621	2	effects	effect	NOUN
dti-2185	621	3	of	of	ADP
dti-2185	621	4	cocoa	cocoa	NOUN
dti-2185	621	5	procyanidins	procyanidin	NOUN
dti-2185	621	6	in	in	ADP
dti-2185	621	7	liposomes	liposome	NOUN
dti-2185	621	8	and	and	CCONJ
dti-2185	621	9	jurkat	jurkat	PROPN
dti-2185	621	10	t	t	PROPN
dti-2185	621	11	cells	cell	NOUN
dti-2185	621	12	.	.	PUNCT
dti-2185	622	1	biol	biol	PROPN
dti-2185	622	2	res	re	NOUN
dti-2185	622	3	.	.	PUNCT
dti-2185	623	1	2004;37(2):293	2004;37(2):293	NUM
dti-2185	623	2	-	-	SYM
dti-2185	623	3	300	300	NUM
dti-2185	623	4	.	.	PUNCT
dti-2185	623	5	crossref	crossref	PROPN
dti-2185	623	6	medline	medline	NOUN
dti-2185	623	7	93	93	NUM
dti-2185	623	8	.	.	PUNCT
dti-2185	623	9	verstraeten	verstraeten	VERB
dti-2185	623	10	sv	sv	PROPN
dti-2185	623	11	,	,	PUNCT
dti-2185	623	12	jaggers	jaggers	PROPN
dti-2185	623	13	gk	gk	PROPN
dti-2185	623	14	,	,	PUNCT
dti-2185	623	15	fraga	fraga	NOUN
dti-2185	623	16	cg	cg	PROPN
dti-2185	623	17	,	,	PUNCT
dti-2185	623	18	oteiza	oteiza	NOUN
dti-2185	623	19	pi	pi	NOUN
dti-2185	623	20	.	.	PUNCT
dti-2185	624	1	procyanidins	procyanidin	NOUN
dti-2185	624	2	can	can	AUX
dti-2185	624	3	interact	interact	VERB
dti-2185	624	4	with	with	ADP
dti-2185	624	5	caco-2	caco-2	NUM
dti-2185	624	6	cell	cell	NOUN
dti-2185	624	7	membrane	membrane	NOUN
dti-2185	624	8	lipid	lipid	NOUN
dti-2185	624	9	rafts	raft	NOUN
dti-2185	624	10	:	:	PUNCT
dti-2185	624	11	involvement	involvement	NOUN
dti-2185	624	12	of	of	ADP
dti-2185	624	13	cholesterol	cholesterol	NOUN
dti-2185	624	14	.	.	PUNCT
dti-2185	625	1	biochim	biochim	PROPN
dti-2185	625	2	biophys	biophy	NOUN
dti-2185	625	3	acta	acta	PROPN
dti-2185	625	4	.	.	PUNCT
dti-2185	626	1	2013;1828(11):26462653	2013;1828(11):26462653	X
dti-2185	626	2	.	.	PUNCT
dti-2185	626	3	crossref	crossref	PROPN
dti-2185	626	4	medline	medline	PROPN
dti-2185	626	5	94	94	NUM
dti-2185	626	6	.	.	PUNCT
dti-2185	627	1	neves	neves	PROPN
dti-2185	627	2	ar	ar	PROPN
dti-2185	627	3	,	,	PUNCT
dti-2185	627	4	nunes	nunes	PROPN
dti-2185	627	5	c	c	NOUN
dti-2185	627	6	,	,	PUNCT
dti-2185	627	7	reis	reis	NOUN
dti-2185	627	8	s.	s.	PROPN
dti-2185	627	9	resveratrol	resveratrol	PROPN
dti-2185	627	10	induces	induce	NOUN
dti-2185	627	11	ordered	order	VERB
dti-2185	627	12	domains	domain	NOUN
dti-2185	627	13	formation	formation	NOUN
dti-2185	627	14	in	in	ADP
dti-2185	627	15	biomembranes	biomembrane	NOUN
dti-2185	627	16	:	:	PUNCT
dti-2185	627	17	implication	implication	NOUN
dti-2185	627	18	for	for	ADP
dti-2185	627	19	its	its	PRON
dti-2185	627	20	pleiotropic	pleiotropic	ADJ
dti-2185	627	21	action	action	NOUN
dti-2185	627	22	.	.	PUNCT
dti-2185	628	1	biochim	biochim	PROPN
dti-2185	628	2	biophys	biophy	NOUN
dti-2185	628	3	acta	acta	PROPN
dti-2185	628	4	.	.	PUNCT
dti-2185	629	1	2016;1858(1):12	2016;1858(1):12	NUM
dti-2185	629	2	-	-	SYM
dti-2185	629	3	18	18	NUM
dti-2185	629	4	.	.	PUNCT
dti-2185	629	5	crossref	crossref	PROPN
dti-2185	629	6	medline	medline	NOUN
dti-2185	629	7	95	95	NUM
dti-2185	629	8	.	.	PUNCT
dti-2185	630	1	alves	alves	PROPN
dti-2185	630	2	ds	ds	PROPN
dti-2185	630	3	,	,	PUNCT
dti-2185	630	4	pérez	pérez	NOUN
dti-2185	630	5	-	-	PUNCT
dti-2185	630	6	fons	fon	NOUN
dti-2185	630	7	l	l	NOUN
dti-2185	630	8	,	,	PUNCT
dti-2185	630	9	estepa	estepa	NOUN
dti-2185	630	10	a	a	DET
dti-2185	630	11	,	,	PUNCT
dti-2185	630	12	micol	micol	NOUN
dti-2185	630	13	v.	v.	CCONJ
dti-2185	630	14	membrane	membrane	NOUN
dti-2185	630	15	-	-	PUNCT
dti-2185	630	16	related	relate	VERB
dti-2185	630	17	effects	effect	NOUN
dti-2185	630	18	underlying	underlie	VERB
dti-2185	630	19	the	the	DET
dti-2185	630	20	biological	biological	ADJ
dti-2185	630	21	activity	activity	NOUN
dti-2185	630	22	of	of	ADP
dti-2185	630	23	the	the	DET
dti-2185	630	24	anthraquinones	anthraquinone	NOUN
dti-2185	630	25	emodin	emodin	ADJ
dti-2185	630	26	and	and	CCONJ
dti-2185	630	27	barbaloin	barbaloin	PROPN
dti-2185	630	28	.	.	PUNCT
dti-2185	631	1	biochem	biochem	PROPN
dti-2185	631	2	pharmacol	pharmacol	PROPN
dti-2185	631	3	.	.	PUNCT
dti-2185	632	1	2004;68(3):549561	2004;68(3):549561	NUM
dti-2185	632	2	.	.	PUNCT
dti-2185	633	1	crossref	crossref	PROPN
dti-2185	633	2	medline	medline	NOUN
dti-2185	634	1	96	96	NUM
dti-2185	634	2	.	.	PUNCT
dti-2185	635	1	meng	meng	PROPN
dti-2185	635	2	g	g	PROPN
dti-2185	635	3	,	,	PUNCT
dti-2185	635	4	liu	liu	PROPN
dti-2185	635	5	y	y	PROPN
dti-2185	635	6	,	,	PUNCT
dti-2185	635	7	lou	lou	PROPN
dti-2185	635	8	c	c	PROPN
dti-2185	635	9	,	,	PUNCT
dti-2185	635	10	yang	yang	PROPN
dti-2185	635	11	h.	h.	PROPN
dti-2185	635	12	emodin	emodin	PROPN
dti-2185	635	13	suppresses	suppress	VERB
dti-2185	635	14	lipopolysaccharide	lipopolysaccharide	ADV
dti-2185	635	15	-	-	PUNCT
dti-2185	635	16	induced	induce	VERB
dti-2185	635	17	pro	pro	ADJ
dti-2185	635	18	-	-	ADJ
dti-2185	635	19	inflammatory	inflammatory	ADJ
dti-2185	635	20	responses	response	NOUN
dti-2185	635	21	and	and	CCONJ
dti-2185	635	22	nf	nf	ADJ
dti-2185	635	23	-	-	PUNCT
dti-2185	635	24	κb	κb	NOUN
dti-2185	635	25	activation	activation	NOUN
dti-2185	635	26	by	by	ADP
dti-2185	635	27	disrupting	disrupt	VERB
dti-2185	635	28	lipid	lipid	ADJ
dti-2185	635	29	rafts	raft	NOUN
dti-2185	635	30	in	in	ADP
dti-2185	635	31	cd14	cd14	PROPN
dti-2185	635	32	-	-	PUNCT
dti-2185	635	33	negative	negative	ADJ
dti-2185	635	34	endothelial	endothelial	ADJ
dti-2185	635	35	cells	cell	NOUN
dti-2185	635	36	.	.	PUNCT
dti-2185	636	1	br	br	PROPN
dti-2185	636	2	j	j	PROPN
dti-2185	636	3	pharmacol	pharmacol	PROPN
dti-2185	636	4	.	.	PUNCT
dti-2185	637	1	2010;161(7):1628	2010;161(7):1628	NUM
dti-2185	637	2	-	-	SYM
dti-2185	637	3	1644	1644	NUM
dti-2185	637	4	.	.	PUNCT
dti-2185	638	1	crossref	crossref	PROPN
dti-2185	638	2	medline	medline	PROPN
dti-2185	638	3	97	97	NUM
dti-2185	638	4	.	.	PUNCT
dti-2185	639	1	huang	huang	PROPN
dti-2185	639	2	q	q	PROPN
dti-2185	639	3	,	,	PUNCT
dti-2185	639	4	shen	shen	PROPN
dti-2185	639	5	hm	hm	PROPN
dti-2185	639	6	,	,	PUNCT
dti-2185	639	7	shui	shui	PROPN
dti-2185	639	8	g	g	PROPN
dti-2185	639	9	,	,	PUNCT
dti-2185	639	10	wenk	wenk	PROPN
dti-2185	639	11	mr	mr	PROPN
dti-2185	639	12	,	,	PUNCT
dti-2185	639	13	ong	ong	PROPN
dti-2185	639	14	cn	cn	PROPN
dti-2185	639	15	.	.	PUNCT
dti-2185	639	16	emodin	emodin	PROPN
dti-2185	639	17	inhibits	inhibit	VERB
dti-2185	639	18	tumor	tumor	NOUN
dti-2185	639	19	cell	cell	NOUN
dti-2185	639	20	adhesion	adhesion	NOUN
dti-2185	639	21	through	through	ADP
dti-2185	639	22	disruption	disruption	NOUN
dti-2185	639	23	of	of	ADP
dti-2185	639	24	the	the	DET
dti-2185	639	25	membrane	membrane	NOUN
dti-2185	639	26	lipid	lipid	NOUN
dti-2185	639	27	raft	raft	NOUN
dti-2185	639	28	-	-	PUNCT
dti-2185	639	29	associated	associate	VERB
dti-2185	639	30	integrin	integrin	NOUN
dti-2185	639	31	signaling	signal	VERB
dti-2185	639	32	pathway	pathway	NOUN
dti-2185	639	33	.	.	PUNCT
dti-2185	640	1	cancer	cancer	NOUN
dti-2185	640	2	res	re	NOUN
dti-2185	640	3	.	.	PUNCT
dti-2185	641	1	2006;66(11):5807	2006;66(11):5807	NOUN
dti-2185	641	2	-	-	SYM
dti-2185	641	3	5815	5815	NUM
dti-2185	641	4	.	.	PUNCT
dti-2185	642	1	crossref	crossref	PROPN
dti-2185	642	2	medline	medline	PROPN
dti-2185	642	3	98	98	NUM
dti-2185	642	4	.	.	PUNCT
dti-2185	643	1	yi	yi	PROPN
dti-2185	643	2	js	js	PROPN
dti-2185	643	3	,	,	PUNCT
dti-2185	643	4	choo	choo	PROPN
dti-2185	643	5	hj	hj	PROPN
dti-2185	643	6	,	,	PUNCT
dti-2185	643	7	cho	cho	PROPN
dti-2185	643	8	br	br	PROPN
dti-2185	643	9	,	,	PUNCT
dti-2185	643	10	et	et	PROPN
dti-2185	643	11	al	al	PROPN
dti-2185	643	12	.	.	PUNCT
dti-2185	644	1	ginsenoside	ginsenoside	PROPN
dti-2185	644	2	rh2	rh2	PROPN
dti-2185	644	3	induces	induce	VERB
dti-2185	644	4	ligandindependent	ligandindependent	ADJ
dti-2185	644	5	fas	fas	NOUN
dti-2185	644	6	activation	activation	NOUN
dti-2185	644	7	via	via	ADP
dti-2185	644	8	lipid	lipid	ADJ
dti-2185	644	9	raft	raft	NOUN
dti-2185	644	10	disruption	disruption	NOUN
dti-2185	644	11	.	.	PUNCT
dti-2185	645	1	biochem	biochem	PROPN
dti-2185	645	2	biophys	biophy	VERB
dti-2185	645	3	res	res	PROPN
dti-2185	645	4	commun	commun	PROPN
dti-2185	645	5	.	.	PUNCT
dti-2185	646	1	2009;385(2):154	2009;385(2):154	NUM
dti-2185	646	2	-	-	SYM
dti-2185	646	3	159	159	NUM
dti-2185	646	4	.	.	PUNCT
dti-2185	647	1	crossref	crossref	PROPN
dti-2185	647	2	medline	medline	NOUN
dti-2185	647	3	99	99	NUM
dti-2185	647	4	.	.	PUNCT
dti-2185	648	1	wei	wei	PROPN
dti-2185	648	2	z	z	PROPN
dti-2185	648	3	,	,	PUNCT
dti-2185	648	4	wang	wang	PROPN
dti-2185	648	5	j	j	PROPN
dti-2185	648	6	,	,	PUNCT
dti-2185	648	7	shi	shi	PROPN
dti-2185	648	8	m	m	PROPN
dti-2185	648	9	,	,	PUNCT
dti-2185	648	10	liu	liu	PROPN
dti-2185	648	11	w	w	PROPN
dti-2185	648	12	,	,	PUNCT
dti-2185	648	13	yang	yang	PROPN
dti-2185	648	14	z	z	PROPN
dti-2185	648	15	,	,	PUNCT
dti-2185	648	16	fu	fu	PROPN
dti-2185	648	17	y.	y.	PROPN
dti-2185	648	18	saikosaponin	saikosaponin	PROPN
dti-2185	648	19	a	a	DET
dti-2185	648	20	inhibits	inhibit	VERB
dti-2185	648	21	lps	lps	PROPN
dti-2185	648	22	-	-	PUNCT
dti-2185	648	23	induced	induce	VERB
dti-2185	648	24	inflammatory	inflammatory	ADJ
dti-2185	648	25	response	response	NOUN
dti-2185	648	26	by	by	ADP
dti-2185	648	27	inducing	induce	VERB
dti-2185	648	28	liver	liver	NOUN
dti-2185	648	29	x	x	PUNCT
dti-2185	648	30	receptor	receptor	NOUN
dti-2185	648	31	alpha	alpha	NOUN
dti-2185	648	32	activation	activation	NOUN
dti-2185	648	33	in	in	ADP
dti-2185	648	34	primary	primary	ADJ
dti-2185	648	35	mouse	mouse	NOUN
dti-2185	648	36	macrophages	macrophage	NOUN
dti-2185	648	37	.	.	PUNCT
dti-2185	649	1	oncotarget	oncotarget	NOUN
dti-2185	649	2	.	.	PUNCT
dti-2185	650	1	2016;7(31):48995	2016;7(31):48995	NUM
dti-2185	650	2	-	-	SYM
dti-2185	650	3	49007	49007	NUM
dti-2185	650	4	.	.	PUNCT
dti-2185	651	1	crossref	crossref	PROPN
dti-2185	651	2	medline	medline	PROPN
dti-2185	651	3	100	100	NUM
dti-2185	651	4	.	.	PUNCT
dti-2185	652	1	murai	murai	PROPN
dti-2185	652	2	t.	t.	NOUN
dti-2185	653	1	the	the	DET
dti-2185	653	2	role	role	NOUN
dti-2185	653	3	of	of	ADP
dti-2185	653	4	lipid	lipid	ADJ
dti-2185	653	5	rafts	raft	NOUN
dti-2185	653	6	in	in	ADP
dti-2185	653	7	cancer	cancer	NOUN
dti-2185	653	8	cell	cell	NOUN
dti-2185	653	9	adhesion	adhesion	NOUN
dti-2185	653	10	and	and	CCONJ
dti-2185	653	11	migration	migration	NOUN
dti-2185	653	12	.	.	PUNCT
dti-2185	654	1	int	int	NOUN
dti-2185	654	2	j	j	PROPN
dti-2185	654	3	cell	cell	NOUN
dti-2185	654	4	biol	biol	NOUN
dti-2185	654	5	.	.	PUNCT
dti-2185	655	1	2012;2012:763283	2012;2012:763283	NUM
dti-2185	655	2	.	.	PUNCT
dti-2185	656	1	crossref	crossref	PROPN
dti-2185	656	2	medline	medline	NOUN
dti-2185	656	3	101	101	NUM
dti-2185	656	4	.	.	PUNCT
dti-2185	657	1	li	li	PROPN
dti-2185	657	2	yc	yc	PROPN
dti-2185	657	3	,	,	PUNCT
dti-2185	657	4	park	park	PROPN
dti-2185	657	5	mj	mj	PROPN
dti-2185	657	6	,	,	PUNCT
dti-2185	657	7	ye	ye	PROPN
dti-2185	657	8	sk	sk	PROPN
dti-2185	657	9	,	,	PUNCT
dti-2185	657	10	kim	kim	PROPN
dti-2185	657	11	cw	cw	PROPN
dti-2185	657	12	,	,	PUNCT
dti-2185	657	13	kim	kim	PROPN
dti-2185	657	14	yn	yn	PROPN
dti-2185	657	15	.	.	PROPN
dti-2185	657	16	elevated	elevate	VERB
dti-2185	657	17	levels	level	NOUN
dti-2185	657	18	of	of	ADP
dti-2185	657	19	cholesterol	cholesterol	NOUN
dti-2185	657	20	-	-	PUNCT
dti-2185	657	21	rich	rich	ADJ
dti-2185	657	22	lipid	lipid	NOUN
dti-2185	657	23	rafts	raft	NOUN
dti-2185	657	24	in	in	ADP
dti-2185	657	25	cancer	cancer	NOUN
dti-2185	657	26	cells	cell	NOUN
dti-2185	657	27	are	be	AUX
dti-2185	657	28	correlated	correlate	VERB
dti-2185	657	29	with	with	ADP
dti-2185	657	30	apoptosis	apoptosis	NOUN
dti-2185	657	31	sensitivity	sensitivity	NOUN
dti-2185	657	32	induced	induce	VERB
dti-2185	657	33	by	by	ADP
dti-2185	657	34	cholesterol	cholesterol	NOUN
dti-2185	657	35	-	-	PUNCT
dti-2185	657	36	depleting	deplete	VERB
dti-2185	657	37	agents	agent	NOUN
dti-2185	657	38	.	.	PUNCT
dti-2185	658	1	am	be	AUX
dti-2185	658	2	j	j	PROPN
dti-2185	658	3	pathol	pathol	NOUN
dti-2185	658	4	.	.	PUNCT
dti-2185	659	1	2006;168(4):1107	2006;168(4):1107	NUM
dti-2185	659	2	-	-	SYM
dti-2185	659	3	1118	1118	NUM
dti-2185	659	4	.	.	PUNCT
dti-2185	660	1	crossref	crossref	PROPN
dti-2185	660	2	medline	medline	PROPN
dti-2185	660	3	102	102	NUM
dti-2185	660	4	.	.	PUNCT
dti-2185	661	1	zhang	zhang	PROPN
dti-2185	661	2	h	h	PROPN
dti-2185	661	3	,	,	PUNCT
dti-2185	661	4	penninger	penninger	PROPN
dti-2185	661	5	jm	jm	PROPN
dti-2185	661	6	,	,	PUNCT
dti-2185	661	7	li	li	PROPN
dti-2185	661	8	y	y	PROPN
dti-2185	661	9	,	,	PUNCT
dti-2185	661	10	zhong	zhong	PROPN
dti-2185	661	11	n	n	CCONJ
dti-2185	661	12	,	,	PUNCT
dti-2185	661	13	slutsky	slutsky	PROPN
dti-2185	661	14	as	as	ADP
dti-2185	661	15	.	.	PUNCT
dti-2185	661	16	angiotensinconverting	angiotensinconverte	VERB
dti-2185	661	17	enzyme	enzyme	NOUN
dti-2185	661	18	2	2	NUM
dti-2185	661	19	(	(	PUNCT
dti-2185	661	20	ace2	ace2	PROPN
dti-2185	661	21	)	)	PUNCT
dti-2185	661	22	as	as	ADP
dti-2185	661	23	a	a	DET
dti-2185	661	24	sars	sar	NOUN
dti-2185	661	25	-	-	PUNCT
dti-2185	661	26	cov-2	cov-2	NOUN
dti-2185	661	27	receptor	receptor	NOUN
dti-2185	661	28	:	:	PUNCT
dti-2185	661	29	molecular	molecular	ADJ
dti-2185	661	30	mechanisms	mechanism	NOUN
dti-2185	661	31	and	and	CCONJ
dti-2185	661	32	potential	potential	ADJ
dti-2185	661	33	therapeutic	therapeutic	ADJ
dti-2185	661	34	target	target	NOUN
dti-2185	661	35	.	.	PUNCT
dti-2185	662	1	intensive	intensive	ADJ
dti-2185	662	2	care	care	NOUN
dti-2185	662	3	med	me	VERB
dti-2185	662	4	.	.	PUNCT
dti-2185	663	1	2020;46(4):586	2020;46(4):586	NUM
dti-2185	663	2	-	-	PUNCT
dti-2185	663	3	590	590	NUM
dti-2185	663	4	.	.	PUNCT
dti-2185	664	1	crossref	crossref	PROPN
dti-2185	664	2	medline	medline	PROPN
dti-2185	664	3	103	103	NUM
dti-2185	664	4	.	.	PUNCT
dti-2185	665	1	lu	lu	PROPN
dti-2185	665	2	y	y	PROPN
dti-2185	665	3	,	,	PUNCT
dti-2185	665	4	liu	liu	PROPN
dti-2185	665	5	dx	dx	PROPN
dti-2185	665	6	,	,	PUNCT
dti-2185	665	7	tam	tam	PROPN
dti-2185	665	8	jp	jp	PROPN
dti-2185	665	9	.	.	PUNCT
dti-2185	666	1	lipid	lipid	PROPN
dti-2185	666	2	rafts	raft	NOUN
dti-2185	666	3	are	be	AUX
dti-2185	666	4	involved	involve	VERB
dti-2185	666	5	in	in	ADP
dti-2185	666	6	sars	sar	NOUN
dti-2185	666	7	-	-	PUNCT
dti-2185	666	8	cov	cov	NOUN
dti-2185	666	9	entry	entry	NOUN
dti-2185	666	10	into	into	ADP
dti-2185	666	11	vero	vero	PROPN
dti-2185	666	12	e6	e6	PROPN
dti-2185	666	13	cells	cell	NOUN
dti-2185	666	14	.	.	PUNCT
dti-2185	667	1	biochem	biochem	PROPN
dti-2185	667	2	biophys	biophys	PROPN
dti-2185	667	3	res	re	NOUN
dti-2185	667	4	commun	commun	PROPN
dti-2185	667	5	.	.	PUNCT
dti-2185	668	1	2008;369(2):344349	2008;369(2):344349	NUM
dti-2185	668	2	.	.	PUNCT
dti-2185	668	3	crossref	crossref	PROPN
dti-2185	668	4	medline	medline	PROPN
dti-2185	668	5	104	104	NUM
dti-2185	668	6	.	.	PUNCT
dti-2185	669	1	glende	glende	PROPN
dti-2185	669	2	j	j	PROPN
dti-2185	669	3	,	,	PUNCT
dti-2185	669	4	schwegmann	schwegmann	PROPN
dti-2185	669	5	-	-	PUNCT
dti-2185	669	6	wessels	wessels	PROPN
dti-2185	669	7	c	c	PROPN
dti-2185	669	8	,	,	PUNCT
dti-2185	669	9	al	al	PROPN
dti-2185	669	10	-	-	PUNCT
dti-2185	669	11	falah	falah	PROPN
dti-2185	669	12	m	m	PROPN
dti-2185	669	13	,	,	PUNCT
dti-2185	669	14	et	et	PROPN
dti-2185	669	15	al	al	PROPN
dti-2185	669	16	.	.	PUNCT
dti-2185	669	17	importance	importance	NOUN
dti-2185	669	18	of	of	ADP
dti-2185	669	19	cholesterol	cholesterol	NOUN
dti-2185	669	20	-	-	PUNCT
dti-2185	669	21	rich	rich	ADJ
dti-2185	669	22	membrane	membrane	NOUN
dti-2185	669	23	microdomains	microdomain	NOUN
dti-2185	669	24	in	in	ADP
dti-2185	669	25	the	the	DET
dti-2185	669	26	interaction	interaction	NOUN
dti-2185	669	27	of	of	ADP
dti-2185	669	28	the	the	DET
dti-2185	669	29	s	s	NOUN
dti-2185	669	30	protein	protein	NOUN
dti-2185	669	31	of	of	ADP
dti-2185	669	32	sars	sar	NOUN
dti-2185	669	33	-	-	PUNCT
dti-2185	669	34	coronavirus	coronavirus	NOUN
dti-2185	669	35	with	with	ADP
dti-2185	669	36	the	the	DET
dti-2185	669	37	cellular	cellular	ADJ
dti-2185	669	38	receptor	receptor	NOUN
dti-2185	669	39	angiotensin	angiotensin	NOUN
dti-2185	669	40	-	-	PUNCT
dti-2185	669	41	converting	convert	VERB
dti-2185	669	42	enzyme	enzyme	NOUN
dti-2185	669	43	2	2	NUM
dti-2185	669	44	.	.	PUNCT
dti-2185	669	45	virology	virology	NOUN
dti-2185	669	46	.	.	PUNCT
dti-2185	670	1	2008;381(2):215221	2008;381(2):215221	NUM
dti-2185	670	2	.	.	PUNCT
dti-2185	671	1	crossref	crossref	PROPN
dti-2185	671	2	medline	medline	PROPN
dti-2185	671	3	105	105	NUM
dti-2185	671	4	.	.	PUNCT
dti-2185	672	1	wang	wang	PROPN
dti-2185	672	2	h	h	PROPN
dti-2185	672	3	,	,	PUNCT
dti-2185	672	4	yuan	yuan	PROPN
dti-2185	672	5	z	z	PROPN
dti-2185	672	6	,	,	PUNCT
dti-2185	672	7	pavel	pavel	PROPN
dti-2185	672	8	ma	ma	PROPN
dti-2185	672	9	,	,	PUNCT
dti-2185	672	10	hobson	hobson	PROPN
dti-2185	672	11	r	r	PROPN
dti-2185	672	12	,	,	PUNCT
dti-2185	672	13	hansen	hansen	PROPN
dti-2185	672	14	sb	sb	PROPN
dti-2185	672	15	.	.	PUNCT
dti-2185	673	1	the	the	DET
dti-2185	673	2	role	role	NOUN
dti-2185	673	3	of	of	ADP
dti-2185	673	4	high	high	ADJ
dti-2185	673	5	cholesterol	cholesterol	NOUN
dti-2185	673	6	in	in	ADP
dti-2185	673	7	age	age	NOUN
dti-2185	673	8	-	-	PUNCT
dti-2185	673	9	related	relate	VERB
dti-2185	673	10	covid19	covid19	NOUN
dti-2185	673	11	lethality	lethality	NOUN
dti-2185	673	12	.	.	PUNCT
dti-2185	674	1	biorxiv	biorxiv	NOUN
dti-2185	674	2	.	.	PUNCT
dti-2185	675	1	2020.05.09.086249	2020.05.09.086249	NOUN
dti-2185	675	2	.	.	PUNCT
dti-2185	676	1	crossref	crossref	PROPN
dti-2185	676	2	https://doi.org/10.3390/molecules201018923	https://doi.org/10.3390/molecules201018923	PROPN
dti-2185	676	3	https://www.ncbi.nlm.nih.gov/pubmed/26501254	https://www.ncbi.nlm.nih.gov/pubmed/26501254	X
dti-2185	676	4	https://doi.org/10.1016/j.bbamem.2014.01.021	https://doi.org/10.1016/j.bbamem.2014.01.021	VERB
dti-2185	676	5	https://www.ncbi.nlm.nih.gov/pubmed/24472512	https://www.ncbi.nlm.nih.gov/pubmed/24472512	PRON
dti-2185	676	6	https://doi.org/10.1016/j.plipres.2014.11.002	https://doi.org/10.1016/j.plipres.2014.11.002	NOUN
dti-2185	676	7	https://www.ncbi.nlm.nih.gov/pubmed/25479162	https://www.ncbi.nlm.nih.gov/pubmed/25479162	ADV
dti-2185	676	8	https://doi.org/10.1007/s11010-008-9766-9	https://doi.org/10.1007/s11010-008-9766-9	PROPN
dti-2185	676	9	https://www.ncbi.nlm.nih.gov/pubmed/18414995	https://www.ncbi.nlm.nih.gov/pubmed/18414995	NUM
dti-2185	676	10	http://phcogfirst.com/article/869	http://phcogfirst.com/article/869	PROPN
dti-2185	676	11	https://doi.org/10.1158/1535-7163.mct-07-0001	https://doi.org/10.1158/1535-7163.mct-07-0001	PROPN
dti-2185	677	1	https://www.ncbi.nlm.nih.gov/pubmed/17876056	https://www.ncbi.nlm.nih.gov/pubmed/17876056	NUM
dti-2185	677	2	https://doi.org/10.1080/08923970802135690	https://doi.org/10.1080/08923970802135690	VERB
dti-2185	677	3	https://www.ncbi.nlm.nih.gov/pubmed/18720166	https://www.ncbi.nlm.nih.gov/pubmed/18720166	NUM
dti-2185	677	4	https://doi.org/10.1016/j.fct.2013.03.007	https://doi.org/10.1016/j.fct.2013.03.007	ADJ
dti-2185	677	5	https://www.ncbi.nlm.nih.gov/pubmed/23523830	https://www.ncbi.nlm.nih.gov/pubmed/23523830	NUM
dti-2185	677	6	https://doi.org/10.1016/s0009-2797(00)00308-2	https://doi.org/10.1016/s0009-2797(00)00308-2	NOUN
dti-2185	677	7	https://www.ncbi.nlm.nih.gov/pubmed/11248221	https://www.ncbi.nlm.nih.gov/pubmed/11248221	X
dti-2185	677	8	https://doi.org/10.1158/0008-5472.can-07-0411	https://doi.org/10.1158/0008-5472.can-07-0411	NOUN
dti-2185	677	9	https://www.ncbi.nlm.nih.gov/pubmed/17616711	https://www.ncbi.nlm.nih.gov/pubmed/17616711	NOUN
dti-2185	677	10	https://doi.org/10.1002/mc.20649	https://doi.org/10.1002/mc.20649	PRON
dti-2185	677	11	https://www.ncbi.nlm.nih.gov/pubmed/20623641	https://www.ncbi.nlm.nih.gov/pubmed/20623641	X
dti-2185	677	12	https://doi.org/10.1042/bj20111837	https://doi.org/10.1042/bj20111837	X
dti-2185	677	13	https://www.ncbi.nlm.nih.gov/pubmed/22257159	https://www.ncbi.nlm.nih.gov/pubmed/22257159	NUM
dti-2185	677	14	https://doi.org/10.4067/s0716-97602004000200016	https://doi.org/10.4067/s0716-97602004000200016	PROPN
dti-2185	677	15	https://www.ncbi.nlm.nih.gov/pubmed/15455659	https://www.ncbi.nlm.nih.gov/pubmed/15455659	NUM
dti-2185	677	16	https://doi.org/10.1016/j.bbamem.2013.07.023	https://doi.org/10.1016/j.bbamem.2013.07.023	PROPN
dti-2185	677	17	https://www.ncbi.nlm.nih.gov/pubmed/23899501	https://www.ncbi.nlm.nih.gov/pubmed/23899501	NUM
dti-2185	677	18	https://doi.org/10.1016/j.bbamem.2015.10.005	https://doi.org/10.1016/j.bbamem.2015.10.005	PROPN
dti-2185	677	19	https://www.ncbi.nlm.nih.gov/pubmed/26456556	https://www.ncbi.nlm.nih.gov/pubmed/26456556	X
dti-2185	677	20	https://doi.org/10.1016/j.bcp.2004.04.012	https://doi.org/10.1016/j.bcp.2004.04.012	NOUN
dti-2185	677	21	https://www.ncbi.nlm.nih.gov/pubmed/15242821	https://www.ncbi.nlm.nih.gov/pubmed/15242821	NUM
dti-2185	677	22	https://doi.org/10.1111/j.1476-5381.2010.00993.x	https://doi.org/10.1111/j.1476-5381.2010.00993.x	NOUN
dti-2185	677	23	https://www.ncbi.nlm.nih.gov/pubmed/20726986	https://www.ncbi.nlm.nih.gov/pubmed/20726986	X
dti-2185	677	24	https://doi.org/10.1158/0008-5472.can-06-0077	https://doi.org/10.1158/0008-5472.can-06-0077	PROPN
dti-2185	677	25	https://www.ncbi.nlm.nih.gov/pubmed/16740720	https://www.ncbi.nlm.nih.gov/pubmed/16740720	PROPN
dti-2185	677	26	https://doi.org/10.1016/j.bbrc.2009.05.028	https://doi.org/10.1016/j.bbrc.2009.05.028	PROPN
dti-2185	677	27	https://www.ncbi.nlm.nih.gov/pubmed/19445898	https://www.ncbi.nlm.nih.gov/pubmed/19445898	NUM
dti-2185	677	28	https://doi.org/10.18632/oncotarget.9863	https://doi.org/10.18632/oncotarget.9863	ADJ
dti-2185	677	29	https://www.ncbi.nlm.nih.gov/pubmed/27285988	https://www.ncbi.nlm.nih.gov/pubmed/27285988	NUM
dti-2185	677	30	https://doi.org/10.1155/2012/763283	https://doi.org/10.1155/2012/763283	PROPN
dti-2185	677	31	https://www.ncbi.nlm.nih.gov/pubmed/22253629	https://www.ncbi.nlm.nih.gov/pubmed/22253629	NUM
dti-2185	677	32	https://doi.org/10.2353/ajpath.2006.050959	https://doi.org/10.2353/ajpath.2006.050959	PROPN
dti-2185	677	33	https://www.ncbi.nlm.nih.gov/pubmed/16565487	https://www.ncbi.nlm.nih.gov/pubmed/16565487	X
dti-2185	677	34	https://doi.org/10.1007/s00134-020-05985-9	https://doi.org/10.1007/s00134-020-05985-9	NUM
dti-2185	677	35	https://www.ncbi.nlm.nih.gov/pubmed/32125455	https://www.ncbi.nlm.nih.gov/pubmed/32125455	PUNCT
dti-2185	677	36	https://doi.org/10.1016/j.bbrc.2008.02.023	https://doi.org/10.1016/j.bbrc.2008.02.023	PROPN
dti-2185	677	37	https://www.ncbi.nlm.nih.gov/pubmed/18279660	https://www.ncbi.nlm.nih.gov/pubmed/18279660	PROPN
dti-2185	677	38	https://doi.org/10.1016/j.virol.2008.08.026	https://doi.org/10.1016/j.virol.2008.08.026	PROPN
dti-2185	677	39	https://www.ncbi.nlm.nih.gov/pubmed/18814896	https://www.ncbi.nlm.nih.gov/pubmed/18814896	NUM
dti-2185	677	40	https://doi.org/10.1101/2020.05.09.086249	https://doi.org/10.1101/2020.05.09.086249	PROPN