id	sid	tid	token	lemma	pos
dti-2192	1	1	dti	dti	PROPN
dti-2192	1	2	drug	drug	PROPN
dti-2192	1	3	target	target	NOUN
dti-2192	1	4	insights	insight	NOUN
dti-2192	1	5	2021	2021	NUM
dti-2192	1	6	;	;	PUNCT
dti-2192	1	7	15	15	NUM
dti-2192	1	8	:	:	SYM
dti-2192	1	9	5	5	NUM
dti-2192	1	10	-	-	SYM
dti-2192	1	11	12	12	NUM
dti-2192	1	12	issn	issn	PROPN
dti-2192	1	13	1177	1177	NUM
dti-2192	1	14	-	-	SYM
dti-2192	1	15	3928	3928	NUM
dti-2192	1	16	|	|	ADV
dti-2192	1	17	doi	doi	NOUN
dti-2192	1	18	:	:	PUNCT
dti-2192	1	19	10.33393	10.33393	NUM
dti-2192	1	20	/	/	SYM
dti-2192	1	21	dti.2021.2192	dti.2021.2192	NUM
dti-2192	1	22	review	review	VERB
dti-2192	1	23	drug	drug	NOUN
dti-2192	1	24	target	target	NOUN
dti-2192	1	25	insights	insight	NOUN
dti-2192	1	26	issn	issn	VERB
dti-2192	1	27	1177	1177	NUM
dti-2192	1	28	-	-	SYM
dti-2192	1	29	3928	3928	NUM
dti-2192	1	30	www.aboutscience.eu/dti	www.aboutscience.eu/dti	NOUN
dti-2192	1	31	©	©	PROPN
dti-2192	1	32	2021	2021	NUM
dti-2192	1	33	the	the	DET
dti-2192	1	34	authors	author	NOUN
dti-2192	1	35	.	.	PUNCT
dti-2192	2	1	this	this	DET
dti-2192	2	2	article	article	NOUN
dti-2192	2	3	is	be	AUX
dti-2192	2	4	published	publish	VERB
dti-2192	2	5	by	by	ADP
dti-2192	2	6	aboutscience	aboutscience	NOUN
dti-2192	2	7	and	and	CCONJ
dti-2192	2	8	licensed	license	VERB
dti-2192	2	9	under	under	ADP
dti-2192	2	10	creative	creative	ADJ
dti-2192	2	11	commons	common	NOUN
dti-2192	2	12	attribution	attribution	NOUN
dti-2192	2	13	-	-	PUNCT
dti-2192	2	14	noncommercial	noncommercial	ADJ
dti-2192	2	15	4.0	4.0	NUM
dti-2192	2	16	international	international	NOUN
dti-2192	2	17	(	(	PUNCT
dti-2192	2	18	cc	cc	NOUN
dti-2192	2	19	by	by	ADP
dti-2192	2	20	-	-	PUNCT
dti-2192	2	21	nc	nc	PROPN
dti-2192	2	22	4.0	4.0	NUM
dti-2192	2	23	)	)	PUNCT
dti-2192	2	24	.	.	PUNCT
dti-2192	3	1	commercial	commercial	ADJ
dti-2192	3	2	use	use	NOUN
dti-2192	3	3	is	be	AUX
dti-2192	3	4	not	not	PART
dti-2192	3	5	permitted	permit	VERB
dti-2192	3	6	and	and	CCONJ
dti-2192	3	7	is	be	AUX
dti-2192	3	8	subject	subject	ADJ
dti-2192	3	9	to	to	ADP
dti-2192	3	10	publisher	publisher	NOUN
dti-2192	3	11	’s	’s	PART
dti-2192	3	12	permissions	permission	NOUN
dti-2192	3	13	.	.	PUNCT
dti-2192	4	1	full	full	ADJ
dti-2192	4	2	information	information	NOUN
dti-2192	4	3	is	be	AUX
dti-2192	4	4	available	available	ADJ
dti-2192	4	5	at	at	ADP
dti-2192	4	6	www.aboutscience.eu	www.aboutscience.eu	NOUN
dti-2192	4	7	tamarind	tamarind	NOUN
dti-2192	4	8	(	(	PUNCT
dti-2192	4	9	tamarindus	tamarindus	PROPN
dti-2192	4	10	indica	indica	PROPN
dti-2192	4	11	l.	l.	PROPN
dti-2192	4	12	)	)	PUNCT
dti-2192	4	13	seed	seed	NOUN
dti-2192	4	14	a	a	DET
dti-2192	4	15	candidate	candidate	NOUN
dti-2192	4	16	protein	protein	NOUN
dti-2192	4	17	source	source	NOUN
dti-2192	4	18	with	with	ADP
dti-2192	4	19	potential	potential	NOUN
dti-2192	4	20	for	for	ADP
dti-2192	4	21	combating	combat	VERB
dti-2192	4	22	sars	sar	NOUN
dti-2192	4	23	-	-	PUNCT
dti-2192	4	24	cov-2	cov-2	PART
dti-2192	4	25	infection	infection	NOUN
dti-2192	4	26	in	in	ADP
dti-2192	4	27	obesity	obesity	NOUN
dti-2192	4	28	ana	ana	PROPN
dti-2192	4	29	h.	h.	PROPN
dti-2192	4	30	de	de	PROPN
dti-2192	4	31	a.	a.	NOUN
dti-2192	4	32	morais1	morais1	PROPN
dti-2192	4	33	-	-	PUNCT
dti-2192	4	34	3	3	NUM
dti-2192	4	35	,	,	PUNCT
dti-2192	4	36	amanda	amanda	PROPN
dti-2192	4	37	f.	f.	PROPN
dti-2192	4	38	de	de	PROPN
dti-2192	4	39	medeiros1	medeiros1	PROPN
dti-2192	4	40	,	,	PUNCT
dti-2192	4	41	isaiane	isaiane	PROPN
dti-2192	4	42	medeiros1	medeiros1	PROPN
dti-2192	4	43	,	,	PUNCT
dti-2192	5	1	vanessa	vanessa	PROPN
dti-2192	5	2	c.	c.	PROPN
dti-2192	5	3	o.	o.	PROPN
dti-2192	5	4	de	de	PROPN
dti-2192	5	5	lima1	lima1	PROPN
dti-2192	5	6	,	,	PUNCT
dti-2192	5	7	anna	anna	PROPN
dti-2192	5	8	b.	b.	PROPN
dti-2192	5	9	s.	s.	PROPN
dti-2192	5	10	luz1	luz1	PROPN
dti-2192	5	11	,	,	PUNCT
dti-2192	5	12	bruna	bruna	PROPN
dti-2192	5	13	l.	l.	PROPN
dti-2192	5	14	l.	l.	PROPN
dti-2192	5	15	maciel2,3	maciel2,3	PROPN
dti-2192	5	16	,	,	PUNCT
dti-2192	6	1	thaís	thaís	NOUN
dti-2192	6	2	s.	s.	PROPN
dti-2192	6	3	passos3	passos3	PROPN
dti-2192	7	1	1biochemistry	1biochemistry	NUM
dti-2192	7	2	postgraduate	postgraduate	NOUN
dti-2192	7	3	biosciences	bioscience	NOUN
dti-2192	7	4	center	center	NOUN
dti-2192	7	5	,	,	PUNCT
dti-2192	7	6	federal	federal	ADJ
dti-2192	7	7	university	university	PROPN
dti-2192	7	8	of	of	ADP
dti-2192	7	9	rio	rio	PROPN
dti-2192	7	10	grande	grande	PROPN
dti-2192	7	11	do	do	VERB
dti-2192	7	12	norte	norte	NOUN
dti-2192	7	13	,	,	PUNCT
dti-2192	7	14	natal	natal	ADJ
dti-2192	7	15	brazil	brazil	PROPN
dti-2192	7	16	2nutrition	2nutrition	NUM
dti-2192	7	17	postgraduate	postgraduate	NOUN
dti-2192	7	18	program	program	NOUN
dti-2192	7	19	,	,	PUNCT
dti-2192	7	20	center	center	NOUN
dti-2192	7	21	for	for	ADP
dti-2192	7	22	health	health	NOUN
dti-2192	7	23	sciences	sciences	PROPN
dti-2192	7	24	,	,	PUNCT
dti-2192	7	25	federal	federal	ADJ
dti-2192	7	26	university	university	PROPN
dti-2192	7	27	of	of	ADP
dti-2192	7	28	rio	rio	PROPN
dti-2192	7	29	grande	grande	PROPN
dti-2192	7	30	do	do	VERB
dti-2192	7	31	norte	norte	NOUN
dti-2192	7	32	,	,	PUNCT
dti-2192	7	33	natal	natal	PROPN
dti-2192	7	34	brazil	brazil	PROPN
dti-2192	7	35	3department	3department	NUM
dti-2192	7	36	of	of	ADP
dti-2192	7	37	nutrition	nutrition	NOUN
dti-2192	7	38	,	,	PUNCT
dti-2192	7	39	center	center	NOUN
dti-2192	7	40	for	for	ADP
dti-2192	7	41	health	health	NOUN
dti-2192	7	42	sciences	sciences	PROPN
dti-2192	7	43	,	,	PUNCT
dti-2192	7	44	federal	federal	ADJ
dti-2192	7	45	university	university	PROPN
dti-2192	7	46	of	of	ADP
dti-2192	7	47	rio	rio	PROPN
dti-2192	7	48	grande	grande	PROPN
dti-2192	7	49	do	do	AUX
dti-2192	7	50	norte	norte	NOUN
dti-2192	7	51	,	,	PUNCT
dti-2192	7	52	natal	natal	ADJ
dti-2192	7	53	brazil	brazil	PROPN
dti-2192	7	54	all	all	DET
dti-2192	7	55	authors	author	NOUN
dti-2192	7	56	contributed	contribute	VERB
dti-2192	7	57	equally	equally	ADV
dti-2192	7	58	to	to	ADP
dti-2192	7	59	this	this	DET
dti-2192	7	60	work	work	NOUN
dti-2192	7	61	.	.	PUNCT
dti-2192	8	1	abstract	abstract	ADJ
dti-2192	8	2	introduction	introduction	NOUN
dti-2192	8	3	:	:	PUNCT
dti-2192	8	4	obesity	obesity	NOUN
dti-2192	8	5	and	and	CCONJ
dti-2192	8	6	coronavirus	coronavirus	NOUN
dti-2192	8	7	disease	disease	NOUN
dti-2192	8	8	(	(	PUNCT
dti-2192	8	9	covid)-19	covid)-19	PROPN
dti-2192	8	10	are	be	AUX
dti-2192	8	11	overlapping	overlap	VERB
dti-2192	8	12	pandemics	pandemic	NOUN
dti-2192	8	13	,	,	PUNCT
dti-2192	8	14	and	and	CCONJ
dti-2192	8	15	one	one	PRON
dti-2192	8	16	might	might	AUX
dti-2192	8	17	worsen	worsen	VERB
dti-2192	8	18	the	the	DET
dti-2192	8	19	other	other	ADJ
dti-2192	8	20	.	.	PUNCT
dti-2192	9	1	methods	method	NOUN
dti-2192	9	2	:	:	PUNCT
dti-2192	9	3	this	this	DET
dti-2192	9	4	narrative	narrative	NOUN
dti-2192	9	5	review	review	NOUN
dti-2192	9	6	discusses	discuss	VERB
dti-2192	9	7	one	one	NUM
dti-2192	9	8	of	of	ADP
dti-2192	9	9	the	the	DET
dti-2192	9	10	primary	primary	ADJ
dti-2192	9	11	mechanisms	mechanism	NOUN
dti-2192	9	12	to	to	PART
dti-2192	9	13	initiate	initiate	VERB
dti-2192	9	14	acute	acute	ADJ
dti-2192	9	15	respiratory	respiratory	ADJ
dti-2192	9	16	distress	distress	NOUN
dti-2192	9	17	syndrome	syndrome	NOUN
dti-2192	9	18	,	,	PUNCT
dti-2192	9	19	uncontrolled	uncontrolled	ADJ
dti-2192	9	20	systemic	systemic	ADJ
dti-2192	9	21	inflammation	inflammation	NOUN
dti-2192	9	22	in	in	ADP
dti-2192	9	23	covid-19	covid-19	PROPN
dti-2192	9	24	,	,	PUNCT
dti-2192	9	25	and	and	CCONJ
dti-2192	9	26	presents	present	VERB
dti-2192	9	27	a	a	DET
dti-2192	9	28	potential	potential	ADJ
dti-2192	9	29	candidate	candidate	NOUN
dti-2192	9	30	for	for	ADP
dti-2192	9	31	adjuvant	adjuvant	ADJ
dti-2192	9	32	treatment	treatment	NOUN
dti-2192	9	33	.	.	PUNCT
dti-2192	10	1	blocking	block	VERB
dti-2192	10	2	the	the	DET
dti-2192	10	3	s	s	NOUN
dti-2192	10	4	protein	protein	NOUN
dti-2192	10	5	binding	bind	VERB
dti-2192	10	6	to	to	ADP
dti-2192	10	7	angiotensin	angiotensin	NOUN
dti-2192	10	8	-	-	PUNCT
dti-2192	10	9	converting	convert	VERB
dti-2192	10	10	enzyme	enzyme	NOUN
dti-2192	10	11	2	2	NUM
dti-2192	10	12	(	(	PUNCT
dti-2192	10	13	ace-2	ace-2	NUM
dti-2192	10	14	)	)	PUNCT
dti-2192	10	15	and	and	CCONJ
dti-2192	10	16	the	the	DET
dti-2192	10	17	3c	3c	NUM
dti-2192	10	18	-	-	PUNCT
dti-2192	10	19	like	like	ADJ
dti-2192	10	20	protease	protease	NOUN
dti-2192	10	21	(	(	PUNCT
dti-2192	10	22	3cl	3cl	ADJ
dti-2192	10	23	pro	pro	NOUN
dti-2192	10	24	)	)	PUNCT
dti-2192	10	25	is	be	AUX
dti-2192	10	26	an	an	DET
dti-2192	10	27	effective	effective	ADJ
dti-2192	10	28	strategy	strategy	NOUN
dti-2192	10	29	against	against	ADP
dti-2192	10	30	severe	severe	ADJ
dti-2192	10	31	acute	acute	ADJ
dti-2192	10	32	respiratory	respiratory	ADJ
dti-2192	10	33	syndrome	syndrome	NOUN
dti-2192	10	34	coronavirus	coronavirus	NOUN
dti-2192	10	35	2	2	NUM
dti-2192	10	36	(	(	PUNCT
dti-2192	10	37	sars	sar	NOUN
dti-2192	10	38	-	-	PUNCT
dti-2192	10	39	cov-2	cov-2	NOUN
dti-2192	10	40	)	)	PUNCT
dti-2192	10	41	infection	infection	NOUN
dti-2192	10	42	.	.	PUNCT
dti-2192	11	1	results	result	NOUN
dti-2192	11	2	:	:	PUNCT
dti-2192	11	3	host	host	NOUN
dti-2192	11	4	proteases	protease	NOUN
dti-2192	11	5	such	such	ADJ
dti-2192	11	6	as	as	ADP
dti-2192	11	7	furin	furin	NOUN
dti-2192	11	8	,	,	PUNCT
dti-2192	11	9	trypsin	trypsin	NOUN
dti-2192	11	10	,	,	PUNCT
dti-2192	11	11	and	and	CCONJ
dti-2192	11	12	transmembrane	transmembrane	ADJ
dti-2192	11	13	serine	serine	NOUN
dti-2192	11	14	protease	protease	NOUN
dti-2192	11	15	2	2	NUM
dti-2192	11	16	(	(	PUNCT
dti-2192	11	17	tmprss	tmprss	ADJ
dti-2192	11	18	)	)	PUNCT
dti-2192	11	19	act	act	NOUN
dti-2192	11	20	in	in	ADP
dti-2192	11	21	s	s	NOUN
dti-2192	11	22	protein	protein	NOUN
dti-2192	11	23	activation	activation	NOUN
dti-2192	11	24	.	.	PUNCT
dti-2192	12	1	tamarind	tamarind	NOUN
dti-2192	12	2	trypsin	trypsin	NOUN
dti-2192	12	3	inhibitor	inhibitor	NOUN
dti-2192	12	4	(	(	PUNCT
dti-2192	12	5	tti	tti	PROPN
dti-2192	12	6	)	)	PUNCT
dti-2192	12	7	shows	show	VERB
dti-2192	12	8	several	several	ADJ
dti-2192	12	9	beneficial	beneficial	ADJ
dti-2192	12	10	effects	effect	NOUN
dti-2192	12	11	on	on	ADP
dti-2192	12	12	the	the	DET
dti-2192	12	13	reduction	reduction	NOUN
dti-2192	12	14	of	of	ADP
dti-2192	12	15	inflammatory	inflammatory	ADJ
dti-2192	12	16	markers	marker	NOUN
dti-2192	12	17	(	(	PUNCT
dti-2192	12	18	tumor	tumor	NOUN
dti-2192	12	19	necrosis	necrosis	NOUN
dti-2192	12	20	factor	factor	NOUN
dti-2192	13	1	α	α	PROPN
dti-2192	14	1	[	[	X
dti-2192	14	2	tnf	tnf	PROPN
dti-2192	14	3	-	-	PUNCT
dti-2192	14	4	α	α	PROPN
dti-2192	14	5	]	]	X
dti-2192	14	6	,	,	PUNCT
dti-2192	14	7	leptin	leptin	NOUN
dti-2192	14	8	)	)	PUNCT
dti-2192	14	9	and	and	CCONJ
dti-2192	14	10	biochemical	biochemical	ADJ
dti-2192	14	11	parameters	parameter	NOUN
dti-2192	14	12	(	(	PUNCT
dti-2192	14	13	fasting	fast	VERB
dti-2192	14	14	glycemia	glycemia	NOUN
dti-2192	14	15	,	,	PUNCT
dti-2192	14	16	triglycerides	triglyceride	NOUN
dti-2192	14	17	,	,	PUNCT
dti-2192	14	18	and	and	CCONJ
dti-2192	14	19	very	very	ADV
dti-2192	14	20	low	low	ADJ
dti-2192	14	21	-	-	PUNCT
dti-2192	14	22	density	density	NOUN
dti-2192	14	23	lipoprotein	lipoprotein	NOUN
dti-2192	14	24	[	[	X
dti-2192	14	25	vldl	vldl	NOUN
dti-2192	14	26	]	]	X
dti-2192	14	27	)	)	PUNCT
dti-2192	14	28	,	,	PUNCT
dti-2192	14	29	in	in	ADP
dti-2192	14	30	addition	addition	NOUN
dti-2192	14	31	to	to	ADP
dti-2192	14	32	improving	improve	VERB
dti-2192	14	33	pancreatic	pancreatic	ADJ
dti-2192	14	34	function	function	NOUN
dti-2192	14	35	and	and	CCONJ
dti-2192	14	36	mucosal	mucosal	NOUN
dti-2192	14	37	integrity	integrity	NOUN
dti-2192	14	38	in	in	ADP
dti-2192	14	39	an	an	DET
dti-2192	14	40	obesity	obesity	NOUN
dti-2192	14	41	model	model	NOUN
dti-2192	14	42	.	.	PUNCT
dti-2192	15	1	tti	tti	PROPN
dti-2192	15	2	may	may	AUX
dti-2192	15	3	inhibit	inhibit	VERB
dti-2192	15	4	the	the	DET
dti-2192	15	5	action	action	NOUN
dti-2192	15	6	of	of	ADP
dti-2192	15	7	proteases	protease	NOUN
dti-2192	15	8	that	that	PRON
dti-2192	15	9	collaborate	collaborate	VERB
dti-2192	15	10	with	with	ADP
dti-2192	15	11	sars	sar	NOUN
dti-2192	15	12	-	-	PUNCT
dti-2192	15	13	cov-2	cov-2	PART
dti-2192	15	14	infection	infection	NOUN
dti-2192	15	15	and	and	CCONJ
dti-2192	15	16	the	the	DET
dti-2192	15	17	neutrophil	neutrophil	ADJ
dti-2192	15	18	activity	activity	NOUN
dti-2192	15	19	characteristic	characteristic	NOUN
dti-2192	15	20	of	of	ADP
dti-2192	15	21	lung	lung	NOUN
dti-2192	15	22	injury	injury	NOUN
dti-2192	15	23	promoted	promote	VERB
dti-2192	15	24	by	by	ADP
dti-2192	15	25	the	the	DET
dti-2192	15	26	virus	virus	NOUN
dti-2192	15	27	.	.	PUNCT
dti-2192	16	1	conclusion	conclusion	NOUN
dti-2192	16	2	:	:	PUNCT
dti-2192	16	3	thus	thus	ADV
dti-2192	16	4	,	,	PUNCT
dti-2192	16	5	tti	tti	PROPN
dti-2192	16	6	may	may	AUX
dti-2192	16	7	contribute	contribute	VERB
dti-2192	16	8	to	to	ADP
dti-2192	16	9	combating	combat	VERB
dti-2192	16	10	two	two	NUM
dti-2192	16	11	severe	severe	ADJ
dti-2192	16	12	overlapping	overlapping	NOUN
dti-2192	16	13	problems	problem	NOUN
dti-2192	16	14	with	with	ADP
dti-2192	16	15	high	high	ADJ
dti-2192	16	16	cost	cost	NOUN
dti-2192	16	17	and	and	CCONJ
dti-2192	16	18	social	social	ADJ
dti-2192	16	19	complex	complex	ADJ
dti-2192	16	20	implications	implication	NOUN
dti-2192	16	21	,	,	PUNCT
dti-2192	16	22	obesity	obesity	NOUN
dti-2192	16	23	and	and	CCONJ
dti-2192	16	24	covid-19	covid-19	PROPN
dti-2192	16	25	.	.	PUNCT
dti-2192	17	1	keywords	keyword	NOUN
dti-2192	17	2	:	:	PUNCT
dti-2192	18	1	3clpro	3clpro	NUM
dti-2192	18	2	,	,	PUNCT
dti-2192	18	3	ace-2	ace-2	NUM
dti-2192	18	4	,	,	PUNCT
dti-2192	18	5	covid-19	covid-19	PROPN
dti-2192	18	6	,	,	PUNCT
dti-2192	18	7	furin	furin	NOUN
dti-2192	18	8	,	,	PUNCT
dti-2192	18	9	hne	hne	NOUN
dti-2192	18	10	,	,	PUNCT
dti-2192	18	11	inflammation	inflammation	NOUN
dti-2192	18	12	,	,	PUNCT
dti-2192	18	13	tmprss	tmprss	PROPN
dti-2192	18	14	received	receive	VERB
dti-2192	18	15	:	:	PUNCT
dti-2192	18	16	october	october	PROPN
dti-2192	18	17	20	20	NUM
dti-2192	18	18	,	,	PUNCT
dti-2192	18	19	2020	2020	NUM
dti-2192	18	20	accepted	accept	VERB
dti-2192	18	21	:	:	PUNCT
dti-2192	18	22	march	march	PROPN
dti-2192	18	23	11	11	NUM
dti-2192	18	24	,	,	PUNCT
dti-2192	18	25	2021	2021	NUM
dti-2192	18	26	published	publish	VERB
dti-2192	18	27	online	online	ADV
dti-2192	18	28	:	:	PUNCT
dti-2192	18	29	april	april	PROPN
dti-2192	18	30	2	2	NUM
dti-2192	18	31	,	,	PUNCT
dti-2192	18	32	2021	2021	NUM
dti-2192	18	33	corresponding	correspond	VERB
dti-2192	18	34	author	author	NOUN
dti-2192	18	35	:	:	PUNCT
dti-2192	18	36	ana	ana	PROPN
dti-2192	18	37	h.	h.	PROPN
dti-2192	18	38	de	de	PROPN
dti-2192	18	39	a.	a.	PROPN
dti-2192	18	40	morais	morais	PROPN
dti-2192	18	41	department	department	PROPN
dti-2192	18	42	of	of	ADP
dti-2192	18	43	nutrition	nutrition	NOUN
dti-2192	18	44	center	center	NOUN
dti-2192	18	45	for	for	ADP
dti-2192	18	46	health	health	PROPN
dti-2192	18	47	sciences	sciences	PROPN
dti-2192	18	48	federal	federal	PROPN
dti-2192	18	49	university	university	PROPN
dti-2192	18	50	of	of	ADP
dti-2192	18	51	rio	rio	PROPN
dti-2192	18	52	grande	grande	PROPN
dti-2192	18	53	do	do	VERB
dti-2192	18	54	norte	norte	PROPN
dti-2192	18	55	natal	natal	PROPN
dti-2192	18	56	,	,	PUNCT
dti-2192	18	57	rn	rn	PROPN
dti-2192	18	58	59078	59078	NUM
dti-2192	18	59	-	-	SYM
dti-2192	18	60	970	970	NUM
dti-2192	18	61	brazil	brazil	PROPN
dti-2192	18	62	aharaujomorais@gmail.com	aharaujomorais@gmail.com	X
dti-2192	19	1	the	the	DET
dti-2192	19	2	consequences	consequence	NOUN
dti-2192	19	3	of	of	ADP
dti-2192	19	4	sars	sar	NOUN
dti-2192	19	5	-	-	PUNCT
dti-2192	19	6	cov-2	cov-2	PART
dti-2192	19	7	infection	infection	NOUN
dti-2192	19	8	range	range	NOUN
dti-2192	19	9	from	from	ADP
dti-2192	19	10	self	self	NOUN
dti-2192	19	11	-	-	PUNCT
dti-2192	19	12	limited	limit	VERB
dti-2192	19	13	flu	flu	NOUN
dti-2192	19	14	to	to	ADP
dti-2192	19	15	fulminant	fulminant	ADJ
dti-2192	19	16	pneumonia	pneumonia	NOUN
dti-2192	19	17	,	,	PUNCT
dti-2192	19	18	respiratory	respiratory	ADJ
dti-2192	19	19	failure	failure	NOUN
dti-2192	19	20	,	,	PUNCT
dti-2192	19	21	and	and	CCONJ
dti-2192	19	22	death	death	NOUN
dti-2192	19	23	(	(	PUNCT
dti-2192	19	24	4,5	4,5	NUM
dti-2192	19	25	)	)	PUNCT
dti-2192	19	26	.	.	PUNCT
dti-2192	20	1	although	although	SCONJ
dti-2192	20	2	the	the	DET
dti-2192	20	3	new	new	ADJ
dti-2192	20	4	coronavirus	coronavirus	NOUN
dti-2192	20	5	has	have	VERB
dti-2192	20	6	mutations	mutation	NOUN
dti-2192	20	7	,	,	PUNCT
dti-2192	20	8	it	it	PRON
dti-2192	20	9	is	be	AUX
dti-2192	20	10	still	still	ADV
dti-2192	20	11	unclear	unclear	ADJ
dti-2192	20	12	whether	whether	SCONJ
dti-2192	20	13	they	they	PRON
dti-2192	20	14	are	be	AUX
dti-2192	20	15	related	relate	VERB
dti-2192	20	16	to	to	ADP
dti-2192	20	17	its	its	PRON
dti-2192	20	18	virulence	virulence	NOUN
dti-2192	20	19	(	(	PUNCT
dti-2192	20	20	6	6	NUM
dti-2192	20	21	)	)	PUNCT
dti-2192	20	22	,	,	PUNCT
dti-2192	20	23	which	which	PRON
dti-2192	20	24	might	might	AUX
dti-2192	20	25	soon	soon	ADV
dti-2192	20	26	be	be	AUX
dti-2192	20	27	answered	answer	VERB
dti-2192	20	28	through	through	ADP
dti-2192	20	29	ongoing	ongoing	ADJ
dti-2192	20	30	studies	study	NOUN
dti-2192	20	31	(	(	PUNCT
dti-2192	20	32	7	7	NUM
dti-2192	20	33	)	)	PUNCT
dti-2192	20	34	.	.	PUNCT
dti-2192	21	1	advanced	advanced	ADJ
dti-2192	21	2	age	age	NOUN
dti-2192	21	3	is	be	AUX
dti-2192	21	4	a	a	DET
dti-2192	21	5	risk	risk	NOUN
dti-2192	21	6	factor	factor	NOUN
dti-2192	21	7	that	that	PRON
dti-2192	21	8	leads	lead	VERB
dti-2192	21	9	to	to	ADP
dti-2192	21	10	the	the	DET
dti-2192	21	11	worsening	worsening	NOUN
dti-2192	21	12	of	of	ADP
dti-2192	21	13	the	the	DET
dti-2192	21	14	clinical	clinical	ADJ
dti-2192	21	15	condition	condition	NOUN
dti-2192	21	16	of	of	ADP
dti-2192	21	17	the	the	DET
dti-2192	21	18	disease	disease	NOUN
dti-2192	21	19	,	,	PUNCT
dti-2192	21	20	placing	place	VERB
dti-2192	21	21	the	the	DET
dti-2192	21	22	elderly	elderly	ADJ
dti-2192	21	23	as	as	ADP
dti-2192	21	24	a	a	DET
dti-2192	21	25	vulnerable	vulnerable	ADJ
dti-2192	21	26	population	population	NOUN
dti-2192	21	27	with	with	ADP
dti-2192	21	28	a	a	DET
dti-2192	21	29	high	high	ADJ
dti-2192	21	30	risk	risk	NOUN
dti-2192	21	31	of	of	ADP
dti-2192	21	32	death	death	NOUN
dti-2192	21	33	.	.	PUNCT
dti-2192	22	1	however	however	ADV
dti-2192	22	2	,	,	PUNCT
dti-2192	22	3	severe	severe	ADJ
dti-2192	22	4	cases	case	NOUN
dti-2192	22	5	also	also	ADV
dti-2192	22	6	occur	occur	VERB
dti-2192	22	7	in	in	ADP
dti-2192	22	8	middle	middle	NOUN
dti-2192	22	9	-	-	PUNCT
dti-2192	22	10	aged	aged	ADJ
dti-2192	22	11	or	or	CCONJ
dti-2192	22	12	younger	young	ADJ
dti-2192	22	13	people	people	NOUN
dti-2192	22	14	,	,	PUNCT
dti-2192	22	15	and	and	CCONJ
dti-2192	22	16	one	one	NUM
dti-2192	22	17	of	of	ADP
dti-2192	22	18	the	the	DET
dti-2192	22	19	possible	possible	ADJ
dti-2192	22	20	contributing	contributing	NOUN
dti-2192	22	21	factors	factor	NOUN
dti-2192	22	22	for	for	ADP
dti-2192	22	23	this	this	PRON
dti-2192	22	24	is	be	AUX
dti-2192	22	25	the	the	DET
dti-2192	22	26	already	already	ADV
dti-2192	22	27	known	know	VERB
dti-2192	22	28	relationship	relationship	NOUN
dti-2192	22	29	between	between	ADP
dti-2192	22	30	nutritional	nutritional	ADJ
dti-2192	22	31	status	status	NOUN
dti-2192	22	32	and	and	CCONJ
dti-2192	22	33	the	the	DET
dti-2192	22	34	prognosis	prognosis	NOUN
dti-2192	22	35	of	of	ADP
dti-2192	22	36	viral	viral	ADJ
dti-2192	22	37	infections	infection	NOUN
dti-2192	22	38	,	,	PUNCT
dti-2192	22	39	which	which	PRON
dti-2192	22	40	can	can	AUX
dti-2192	22	41	contribute	contribute	VERB
dti-2192	22	42	to	to	ADP
dti-2192	22	43	the	the	DET
dti-2192	22	44	improvement	improvement	NOUN
dti-2192	22	45	or	or	CCONJ
dti-2192	22	46	worsening	worsening	NOUN
dti-2192	22	47	of	of	ADP
dti-2192	22	48	the	the	DET
dti-2192	22	49	disease	disease	NOUN
dti-2192	22	50	(	(	PUNCT
dti-2192	22	51	8	8	NUM
dti-2192	22	52	-	-	SYM
dti-2192	22	53	10	10	NUM
dti-2192	22	54	)	)	PUNCT
dti-2192	22	55	.	.	PUNCT
dti-2192	23	1	according	accord	VERB
dti-2192	23	2	to	to	ADP
dti-2192	23	3	butler	butler	PROPN
dti-2192	23	4	et	et	PROPN
dti-2192	23	5	al	al	PROPN
dti-2192	23	6	(	(	PUNCT
dti-2192	23	7	11	11	NUM
dti-2192	23	8	)	)	PUNCT
dti-2192	23	9	and	and	CCONJ
dti-2192	23	10	muscogiuri	muscogiuri	PROPN
dti-2192	23	11	et	et	PROPN
dti-2192	23	12	al	al	PROPN
dti-2192	23	13	(	(	PUNCT
dti-2192	23	14	12	12	NUM
dti-2192	23	15	)	)	PUNCT
dti-2192	23	16	broader	broad	ADJ
dti-2192	23	17	access	access	NOUN
dti-2192	23	18	to	to	ADP
dti-2192	23	19	a	a	DET
dti-2192	23	20	healthy	healthy	ADJ
dti-2192	23	21	and	and	CCONJ
dti-2192	23	22	balanced	balanced	ADJ
dti-2192	23	23	diet	diet	NOUN
dti-2192	23	24	rich	rich	ADJ
dti-2192	23	25	in	in	ADP
dti-2192	23	26	vitamins	vitamin	NOUN
dti-2192	23	27	,	,	PUNCT
dti-2192	23	28	minerals	mineral	NOUN
dti-2192	23	29	,	,	PUNCT
dti-2192	23	30	bioactive	bioactive	PROPN
dti-2192	23	31	compounds	compound	NOUN
dti-2192	23	32	,	,	PUNCT
dti-2192	23	33	and	and	CCONJ
dti-2192	23	34	antioxidants	antioxidant	NOUN
dti-2192	23	35	is	be	AUX
dti-2192	23	36	essential	essential	ADJ
dti-2192	23	37	to	to	PART
dti-2192	23	38	assist	assist	VERB
dti-2192	23	39	in	in	ADP
dti-2192	23	40	reducing	reduce	VERB
dti-2192	23	41	susceptibility	susceptibility	NOUN
dti-2192	23	42	to	to	ADP
dti-2192	23	43	sars	sar	NOUN
dti-2192	23	44	-	-	PUNCT
dti-2192	23	45	cov-2	cov-2	PART
dti-2192	23	46	infection	infection	NOUN
dti-2192	23	47	,	,	PUNCT
dti-2192	23	48	in	in	ADP
dti-2192	23	49	addition	addition	NOUN
dti-2192	23	50	to	to	ADP
dti-2192	23	51	the	the	DET
dti-2192	23	52	complications	complication	NOUN
dti-2192	23	53	that	that	PRON
dti-2192	23	54	can	can	AUX
dti-2192	23	55	occur	occur	VERB
dti-2192	23	56	in	in	ADP
dti-2192	23	57	the	the	DET
dti-2192	23	58	long	long	ADJ
dti-2192	23	59	term	term	NOUN
dti-2192	23	60	.	.	PUNCT
dti-2192	24	1	the	the	DET
dti-2192	24	2	regional	regional	ADJ
dti-2192	24	3	councils	council	NOUN
dti-2192	24	4	of	of	ADP
dti-2192	24	5	the	the	DET
dti-2192	24	6	four	four	NUM
dti-2192	24	7	united	united	PROPN
dti-2192	24	8	nations	nations	PROPN
dti-2192	24	9	agencies	agency	NOUN
dti-2192	24	10	(	(	PUNCT
dti-2192	24	11	food	food	NOUN
dti-2192	24	12	and	and	CCONJ
dti-2192	24	13	agriculture	agriculture	NOUN
dti-2192	24	14	organization	organization	NOUN
dti-2192	24	15	of	of	ADP
dti-2192	24	16	the	the	DET
dti-2192	24	17	united	united	PROPN
dti-2192	24	18	nations	nations	PROPN
dti-2192	24	19	—	—	PUNCT
dti-2192	24	20	fao	fao	PROPN
dti-2192	24	21	,	,	PUNCT
dti-2192	24	22	united	united	PROPN
dti-2192	24	23	nations	nations	PROPN
dti-2192	24	24	children	children	PROPN
dti-2192	24	25	’s	’s	PART
dti-2192	24	26	fund	fund	NOUN
dti-2192	24	27	—	—	PUNCT
dti-2192	24	28	unicef	unicef	PROPN
dti-2192	24	29	,	,	PUNCT
dti-2192	24	30	world	world	NOUN
dti-2192	24	31	health	health	NOUN
dti-2192	24	32	organization	organization	NOUN
dti-2192	24	33	—	—	PUNCT
dti-2192	24	34	who	who	PRON
dti-2192	24	35	,	,	PUNCT
dti-2192	24	36	and	and	CCONJ
dti-2192	24	37	world	world	NOUN
dti-2192	24	38	food	food	NOUN
dti-2192	24	39	program	program	NOUN
dti-2192	24	40	—	—	PUNCT
dti-2192	24	41	wfa	wfa	PROPN
dti-2192	24	42	)	)	PUNCT
dti-2192	24	43	issued	issue	VERB
dti-2192	24	44	introduction	introduction	NOUN
dti-2192	24	45	the	the	DET
dti-2192	24	46	relation	relation	NOUN
dti-2192	24	47	between	between	ADP
dti-2192	24	48	obesity	obesity	NOUN
dti-2192	24	49	and	and	CCONJ
dti-2192	24	50	severe	severe	ADJ
dti-2192	24	51	covid-19	covid-19	PROPN
dti-2192	24	52	coronavirus	coronavirus	NOUN
dti-2192	24	53	disease	disease	NOUN
dti-2192	24	54	(	(	PUNCT
dti-2192	24	55	covid)-19	covid)-19	PROPN
dti-2192	24	56	pandemic	pandemic	ADJ
dti-2192	24	57	,	,	PUNCT
dti-2192	24	58	caused	cause	VERB
dti-2192	24	59	by	by	ADP
dti-2192	24	60	severe	severe	ADJ
dti-2192	24	61	acute	acute	ADJ
dti-2192	24	62	respiratory	respiratory	ADJ
dti-2192	24	63	syndrome	syndrome	NOUN
dti-2192	24	64	coronavirus	coronavirus	NOUN
dti-2192	24	65	2	2	NUM
dti-2192	24	66	(	(	PUNCT
dti-2192	24	67	sars	sar	NOUN
dti-2192	24	68	-	-	PUNCT
dti-2192	24	69	cov-2	cov-2	NOUN
dti-2192	24	70	)	)	PUNCT
dti-2192	24	71	coronavirus	coronavirus	NOUN
dti-2192	24	72	,	,	PUNCT
dti-2192	24	73	is	be	AUX
dti-2192	24	74	a	a	DET
dti-2192	24	75	serious	serious	ADJ
dti-2192	24	76	threat	threat	NOUN
dti-2192	24	77	to	to	ADP
dti-2192	24	78	health	health	NOUN
dti-2192	24	79	systems	system	NOUN
dti-2192	24	80	around	around	ADP
dti-2192	24	81	the	the	DET
dti-2192	24	82	world	world	NOUN
dti-2192	24	83	.	.	PUNCT
dti-2192	25	1	it	it	PRON
dti-2192	25	2	overlaps	overlap	VERB
dti-2192	25	3	with	with	ADP
dti-2192	25	4	obesity	obesity	NOUN
dti-2192	25	5	,	,	PUNCT
dti-2192	25	6	another	another	DET
dti-2192	25	7	global	global	ADJ
dti-2192	25	8	pandemic	pandemic	ADJ
dti-2192	25	9	(	(	PUNCT
dti-2192	25	10	1	1	NUM
dti-2192	25	11	-	-	SYM
dti-2192	25	12	3	3	NUM
dti-2192	25	13	)	)	PUNCT
dti-2192	25	14	.	.	PUNCT
dti-2192	26	1	sars	sar	NOUN
dti-2192	26	2	-	-	PUNCT
dti-2192	26	3	cov-2	cov-2	PART
dti-2192	26	4	infection	infection	NOUN
dti-2192	26	5	started	start	VERB
dti-2192	26	6	in	in	ADP
dti-2192	26	7	december	december	PROPN
dti-2192	26	8	2019	2019	NUM
dti-2192	26	9	and	and	CCONJ
dti-2192	26	10	spread	spread	VERB
dti-2192	26	11	rapidly	rapidly	ADV
dti-2192	26	12	because	because	SCONJ
dti-2192	26	13	its	its	PRON
dti-2192	26	14	transmission	transmission	NOUN
dti-2192	26	15	occurs	occur	VERB
dti-2192	26	16	through	through	ADP
dti-2192	26	17	the	the	DET
dti-2192	26	18	airways	airway	NOUN
dti-2192	26	19	.	.	PUNCT
dti-2192	27	1	https://doi.org/10.33393/dti.2021.2192	https://doi.org/10.33393/dti.2021.2192	PRON
dti-2192	27	2	https://creativecommons.org/licenses/by-nc/4.0/legalcode	https://creativecommons.org/licenses/by-nc/4.0/legalcode	NUM
dti-2192	27	3	protein	protein	NOUN
dti-2192	27	4	with	with	ADP
dti-2192	27	5	potential	potential	NOUN
dti-2192	27	6	for	for	ADP
dti-2192	27	7	combating	combat	VERB
dti-2192	27	8	sars	sar	NOUN
dti-2192	27	9	-	-	PUNCT
dti-2192	27	10	cov-2	cov-2	PART
dti-2192	27	11	infection	infection	NOUN
dti-2192	27	12	in	in	ADP
dti-2192	27	13	obesity6	obesity6	PROPN
dti-2192	28	1	©	©	PROPN
dti-2192	28	2	2021	2021	NUM
dti-2192	29	1	the	the	DET
dti-2192	29	2	authors	author	NOUN
dti-2192	29	3	.	.	PUNCT
dti-2192	30	1	drug	drug	NOUN
dti-2192	30	2	target	target	NOUN
dti-2192	30	3	insights	insight	NOUN
dti-2192	30	4	issn	issn	VERB
dti-2192	30	5	1177	1177	NUM
dti-2192	30	6	-	-	SYM
dti-2192	30	7	3928	3928	NUM
dti-2192	30	8	www.aboutscience.eu/dti	www.aboutscience.eu/dti	VERB
dti-2192	30	9	a	a	DET
dti-2192	30	10	joint	joint	ADJ
dti-2192	30	11	statement	statement	NOUN
dti-2192	30	12	on	on	ADP
dti-2192	30	13	nutrition	nutrition	NOUN
dti-2192	30	14	in	in	ADP
dti-2192	30	15	the	the	DET
dti-2192	30	16	context	context	NOUN
dti-2192	30	17	of	of	ADP
dti-2192	30	18	the	the	DET
dti-2192	30	19	covid-19	covid-19	PROPN
dti-2192	30	20	pandemic	pandemic	NOUN
dti-2192	30	21	in	in	ADP
dti-2192	30	22	asia	asia	PROPN
dti-2192	30	23	and	and	CCONJ
dti-2192	30	24	the	the	DET
dti-2192	30	25	pacific	pacific	PROPN
dti-2192	30	26	.	.	PUNCT
dti-2192	31	1	the	the	DET
dti-2192	31	2	recommendations	recommendation	NOUN
dti-2192	31	3	emphasized	emphasize	VERB
dti-2192	31	4	the	the	DET
dti-2192	31	5	need	need	NOUN
dti-2192	31	6	for	for	ADP
dti-2192	31	7	continuous	continuous	ADJ
dti-2192	31	8	adoption	adoption	NOUN
dti-2192	31	9	of	of	ADP
dti-2192	31	10	advice	advice	NOUN
dti-2192	31	11	and	and	CCONJ
dti-2192	31	12	strategies	strategy	NOUN
dti-2192	31	13	ensuring	ensure	VERB
dti-2192	31	14	nutritional	nutritional	ADJ
dti-2192	31	15	surveillance	surveillance	NOUN
dti-2192	31	16	,	,	PUNCT
dti-2192	31	17	food	food	NOUN
dti-2192	31	18	quality	quality	NOUN
dti-2192	31	19	,	,	PUNCT
dti-2192	31	20	and	and	CCONJ
dti-2192	31	21	food	food	NOUN
dti-2192	31	22	security	security	NOUN
dti-2192	31	23	.	.	PUNCT
dti-2192	32	1	on	on	ADP
dti-2192	32	2	the	the	DET
dti-2192	32	3	other	other	ADJ
dti-2192	32	4	hand	hand	NOUN
dti-2192	32	5	,	,	PUNCT
dti-2192	32	6	the	the	DET
dti-2192	32	7	current	current	ADJ
dti-2192	32	8	moment	moment	NOUN
dti-2192	32	9	demands	demand	VERB
dti-2192	32	10	the	the	DET
dti-2192	32	11	isolation	isolation	NOUN
dti-2192	32	12	of	of	ADP
dti-2192	32	13	the	the	DET
dti-2192	32	14	world	world	NOUN
dti-2192	32	15	population	population	NOUN
dti-2192	32	16	as	as	ADP
dti-2192	32	17	a	a	DET
dti-2192	32	18	strategy	strategy	NOUN
dti-2192	32	19	to	to	PART
dti-2192	32	20	contain	contain	VERB
dti-2192	32	21	the	the	DET
dti-2192	32	22	infection	infection	NOUN
dti-2192	32	23	spread	spread	NOUN
dti-2192	32	24	.	.	PUNCT
dti-2192	33	1	isolation	isolation	NOUN
dti-2192	33	2	can	can	AUX
dti-2192	33	3	increases	increase	VERB
dti-2192	33	4	consumers	consumer	NOUN
dti-2192	33	5	’	'	PUNCT
dti-2192	33	6	preference	preference	NOUN
dti-2192	33	7	for	for	ADP
dti-2192	33	8	industrialized	industrialized	ADJ
dti-2192	33	9	and	and	CCONJ
dti-2192	33	10	ultra	ultra	ADJ
dti-2192	33	11	-	-	ADJ
dti-2192	33	12	processed	process	VERB
dti-2192	33	13	foods	food	NOUN
dti-2192	33	14	.	.	PUNCT
dti-2192	34	1	this	this	DET
dti-2192	34	2	preference	preference	NOUN
dti-2192	34	3	occurs	occur	VERB
dti-2192	34	4	due	due	ADJ
dti-2192	34	5	to	to	ADP
dti-2192	34	6	the	the	DET
dti-2192	34	7	practicality	practicality	NOUN
dti-2192	34	8	,	,	PUNCT
dti-2192	34	9	hygienic	hygienic	ADJ
dti-2192	34	10	safety	safety	NOUN
dti-2192	34	11	,	,	PUNCT
dti-2192	34	12	longer	long	ADJ
dti-2192	34	13	shelf	shelf	NOUN
dti-2192	34	14	life	life	NOUN
dti-2192	34	15	,	,	PUNCT
dti-2192	34	16	of	of	ADP
dti-2192	34	17	industrialized	industrialized	ADJ
dti-2192	34	18	and	and	CCONJ
dti-2192	34	19	ultra	ultra	ADJ
dti-2192	34	20	-	-	ADJ
dti-2192	34	21	processed	process	VERB
dti-2192	34	22	foods	food	NOUN
dti-2192	34	23	compared	compare	VERB
dti-2192	34	24	to	to	ADP
dti-2192	34	25	fresh	fresh	ADJ
dti-2192	34	26	and	and	CCONJ
dti-2192	34	27	unprocessed	unprocessed	ADJ
dti-2192	34	28	products	product	NOUN
dti-2192	34	29	(	(	PUNCT
dti-2192	34	30	13	13	NUM
dti-2192	34	31	)	)	PUNCT
dti-2192	34	32	.	.	PUNCT
dti-2192	35	1	this	this	DET
dti-2192	35	2	possible	possible	ADJ
dti-2192	35	3	trend	trend	NOUN
dti-2192	35	4	may	may	AUX
dti-2192	35	5	increase	increase	VERB
dti-2192	35	6	food	food	NOUN
dti-2192	35	7	insecurity	insecurity	NOUN
dti-2192	35	8	and	and	CCONJ
dti-2192	35	9	directly	directly	ADV
dti-2192	35	10	impact	impact	VERB
dti-2192	35	11	weight	weight	NOUN
dti-2192	35	12	gain	gain	NOUN
dti-2192	35	13	(	(	PUNCT
dti-2192	35	14	13	13	NUM
dti-2192	35	15	-	-	SYM
dti-2192	35	16	16	16	NUM
dti-2192	35	17	)	)	PUNCT
dti-2192	35	18	,	,	PUNCT
dti-2192	35	19	increasing	increase	VERB
dti-2192	35	20	the	the	DET
dti-2192	35	21	risk	risk	NOUN
dti-2192	35	22	of	of	ADP
dti-2192	35	23	overweight	overweight	NOUN
dti-2192	35	24	and	and	CCONJ
dti-2192	35	25	obesity	obesity	NOUN
dti-2192	35	26	,	,	PUNCT
dti-2192	35	27	which	which	PRON
dti-2192	35	28	can	can	AUX
dti-2192	35	29	persist	persist	VERB
dti-2192	35	30	for	for	ADP
dti-2192	35	31	an	an	DET
dti-2192	35	32	extended	extended	ADJ
dti-2192	35	33	period	period	NOUN
dti-2192	35	34	(	(	PUNCT
dti-2192	35	35	17	17	NUM
dti-2192	35	36	)	)	PUNCT
dti-2192	35	37	.	.	PUNCT
dti-2192	36	1	diet	diet	NOUN
dti-2192	36	2	composition	composition	NOUN
dti-2192	36	3	and	and	CCONJ
dti-2192	36	4	obesity	obesity	NOUN
dti-2192	36	5	have	have	VERB
dti-2192	36	6	a	a	DET
dti-2192	36	7	fundamental	fundamental	ADJ
dti-2192	36	8	role	role	NOUN
dti-2192	36	9	in	in	ADP
dti-2192	36	10	the	the	DET
dti-2192	36	11	coregulation	coregulation	NOUN
dti-2192	36	12	of	of	ADP
dti-2192	36	13	adaptive	adaptive	ADJ
dti-2192	36	14	immunity	immunity	NOUN
dti-2192	36	15	(	(	PUNCT
dti-2192	36	16	18	18	NUM
dti-2192	36	17	)	)	PUNCT
dti-2192	36	18	,	,	PUNCT
dti-2192	36	19	influencing	influence	VERB
dti-2192	36	20	the	the	DET
dti-2192	36	21	modulation	modulation	NOUN
dti-2192	36	22	of	of	ADP
dti-2192	36	23	the	the	DET
dti-2192	36	24	immune	immune	ADJ
dti-2192	36	25	response	response	NOUN
dti-2192	36	26	and	and	CCONJ
dti-2192	36	27	,	,	PUNCT
dti-2192	36	28	consequently	consequently	ADV
dti-2192	36	29	,	,	PUNCT
dti-2192	36	30	affecting	affect	VERB
dti-2192	36	31	the	the	DET
dti-2192	36	32	severity	severity	NOUN
dti-2192	36	33	of	of	ADP
dti-2192	36	34	respiratory	respiratory	ADJ
dti-2192	36	35	diseases	disease	NOUN
dti-2192	36	36	and	and	CCONJ
dti-2192	36	37	other	other	ADJ
dti-2192	36	38	infections	infection	NOUN
dti-2192	36	39	(	(	PUNCT
dti-2192	36	40	9	9	NUM
dti-2192	36	41	)	)	PUNCT
dti-2192	36	42	.	.	PUNCT
dti-2192	37	1	in	in	ADP
dti-2192	37	2	general	general	ADJ
dti-2192	37	3	,	,	PUNCT
dti-2192	37	4	adiposity	adiposity	NOUN
dti-2192	37	5	can	can	AUX
dti-2192	37	6	impair	impair	VERB
dti-2192	37	7	the	the	DET
dti-2192	37	8	ventilation	ventilation	NOUN
dti-2192	37	9	of	of	ADP
dti-2192	37	10	the	the	DET
dti-2192	37	11	base	base	NOUN
dti-2192	37	12	of	of	ADP
dti-2192	37	13	the	the	DET
dti-2192	37	14	lungs	lung	NOUN
dti-2192	37	15	,	,	PUNCT
dti-2192	37	16	resulting	result	VERB
dti-2192	37	17	in	in	ADP
dti-2192	37	18	less	less	ADJ
dti-2192	37	19	oxygen	oxygen	NOUN
dti-2192	37	20	saturation	saturation	NOUN
dti-2192	37	21	in	in	ADP
dti-2192	37	22	the	the	DET
dti-2192	37	23	blood	blood	NOUN
dti-2192	37	24	(	(	PUNCT
dti-2192	37	25	19	19	NUM
dti-2192	37	26	)	)	PUNCT
dti-2192	37	27	.	.	PUNCT
dti-2192	38	1	thus	thus	ADV
dti-2192	38	2	,	,	PUNCT
dti-2192	38	3	in	in	ADP
dti-2192	38	4	covid-19	covid-19	PROPN
dti-2192	38	5	,	,	PUNCT
dti-2192	38	6	the	the	DET
dti-2192	38	7	need	need	NOUN
dti-2192	38	8	for	for	ADP
dti-2192	38	9	treatment	treatment	NOUN
dti-2192	38	10	in	in	ADP
dti-2192	38	11	intensive	intensive	ADJ
dti-2192	38	12	care	care	NOUN
dti-2192	38	13	units	unit	NOUN
dti-2192	38	14	(	(	PUNCT
dti-2192	38	15	icus	icus	NOUN
dti-2192	38	16	)	)	PUNCT
dti-2192	38	17	increases	increase	NOUN
dti-2192	38	18	,	,	PUNCT
dti-2192	38	19	and	and	CCONJ
dti-2192	38	20	intubations	intubation	NOUN
dti-2192	38	21	are	be	AUX
dti-2192	38	22	technically	technically	ADV
dti-2192	38	23	more	more	ADV
dti-2192	38	24	challenging	challenging	ADJ
dti-2192	38	25	in	in	ADP
dti-2192	38	26	obese	obese	ADJ
dti-2192	38	27	patients	patient	NOUN
dti-2192	38	28	,	,	PUNCT
dti-2192	38	29	in	in	ADP
dti-2192	38	30	addition	addition	NOUN
dti-2192	38	31	to	to	ADP
dti-2192	38	32	the	the	DET
dti-2192	38	33	difficulty	difficulty	NOUN
dti-2192	38	34	in	in	ADP
dti-2192	38	35	obtaining	obtain	VERB
dti-2192	38	36	a	a	DET
dti-2192	38	37	diagnosis	diagnosis	NOUN
dti-2192	38	38	by	by	ADP
dti-2192	38	39	imaging	image	VERB
dti-2192	38	40	techniques	technique	NOUN
dti-2192	38	41	.	.	PUNCT
dti-2192	39	1	according	accord	VERB
dti-2192	39	2	to	to	ADP
dti-2192	39	3	the	the	DET
dti-2192	39	4	review	review	NOUN
dti-2192	39	5	study	study	NOUN
dti-2192	39	6	by	by	ADP
dti-2192	39	7	johnson	johnson	PROPN
dti-2192	39	8	et	et	PROPN
dti-2192	39	9	al	al	PROPN
dti-2192	39	10	(	(	PUNCT
dti-2192	39	11	20	20	NUM
dti-2192	39	12	)	)	PUNCT
dti-2192	39	13	,	,	PUNCT
dti-2192	39	14	obesity	obesity	NOUN
dti-2192	39	15	damages	damage	VERB
dti-2192	39	16	various	various	ADJ
dti-2192	39	17	organs	organ	NOUN
dti-2192	39	18	,	,	PUNCT
dti-2192	39	19	which	which	PRON
dti-2192	39	20	increases	increase	VERB
dti-2192	39	21	the	the	DET
dti-2192	39	22	susceptibility	susceptibility	NOUN
dti-2192	39	23	to	to	ADP
dti-2192	39	24	several	several	ADJ
dti-2192	39	25	diseases	disease	NOUN
dti-2192	39	26	,	,	PUNCT
dti-2192	39	27	such	such	ADJ
dti-2192	39	28	as	as	ADP
dti-2192	39	29	metabolic	metabolic	NOUN
dti-2192	39	30	disorders	disorder	NOUN
dti-2192	39	31	,	,	PUNCT
dti-2192	39	32	cardiovascular	cardiovascular	ADJ
dti-2192	39	33	diseases	disease	NOUN
dti-2192	39	34	,	,	PUNCT
dti-2192	39	35	cancer	cancer	NOUN
dti-2192	39	36	,	,	PUNCT
dti-2192	39	37	and	and	CCONJ
dti-2192	39	38	viral	viral	ADJ
dti-2192	39	39	infections	infection	NOUN
dti-2192	39	40	such	such	ADJ
dti-2192	39	41	as	as	ADP
dti-2192	39	42	influenza	influenza	NOUN
dti-2192	39	43	and	and	CCONJ
dti-2192	39	44	covid-19	covid-19	PROPN
dti-2192	39	45	(	(	PUNCT
dti-2192	39	46	1,21	1,21	PROPN
dti-2192	39	47	)	)	PUNCT
dti-2192	39	48	.	.	PUNCT
dti-2192	40	1	there	there	PRON
dti-2192	40	2	is	be	VERB
dti-2192	40	3	an	an	DET
dti-2192	40	4	intrinsic	intrinsic	ADJ
dti-2192	40	5	relationship	relationship	NOUN
dti-2192	40	6	between	between	ADP
dti-2192	40	7	fat	fat	ADJ
dti-2192	40	8	distribution	distribution	NOUN
dti-2192	40	9	and	and	CCONJ
dti-2192	40	10	metabolic	metabolic	NOUN
dti-2192	40	11	health	health	NOUN
dti-2192	40	12	status	status	NOUN
dti-2192	40	13	.	.	PUNCT
dti-2192	41	1	the	the	DET
dti-2192	41	2	location	location	NOUN
dti-2192	41	3	of	of	ADP
dti-2192	41	4	fat	fat	ADJ
dti-2192	41	5	deposition	deposition	NOUN
dti-2192	41	6	in	in	ADP
dti-2192	41	7	the	the	DET
dti-2192	41	8	body	body	NOUN
dti-2192	41	9	is	be	AUX
dti-2192	41	10	determinant	determinant	ADJ
dti-2192	41	11	for	for	ADP
dti-2192	41	12	health	health	NOUN
dti-2192	41	13	,	,	PUNCT
dti-2192	41	14	and	and	CCONJ
dti-2192	41	15	the	the	DET
dti-2192	41	16	ectopic	ectopic	ADJ
dti-2192	41	17	deposition	deposition	NOUN
dti-2192	41	18	of	of	ADP
dti-2192	41	19	triglycerides	triglyceride	NOUN
dti-2192	41	20	in	in	ADP
dti-2192	41	21	the	the	DET
dti-2192	41	22	abdominal	abdominal	ADJ
dti-2192	41	23	region	region	NOUN
dti-2192	41	24	,	,	PUNCT
dti-2192	41	25	mainly	mainly	ADV
dti-2192	41	26	visceral	visceral	ADJ
dti-2192	41	27	fat	fat	NOUN
dti-2192	41	28	,	,	PUNCT
dti-2192	41	29	causes	cause	VERB
dti-2192	41	30	a	a	DET
dti-2192	41	31	phenotype	phenotype	NOUN
dti-2192	41	32	of	of	ADP
dti-2192	41	33	high	high	ADJ
dti-2192	41	34	cardiometabolic	cardiometabolic	NOUN
dti-2192	41	35	risk	risk	NOUN
dti-2192	41	36	—	—	PUNCT
dti-2192	41	37	even	even	ADV
dti-2192	41	38	for	for	ADP
dti-2192	41	39	individuals	individual	NOUN
dti-2192	41	40	who	who	PRON
dti-2192	41	41	have	have	VERB
dti-2192	41	42	a	a	DET
dti-2192	41	43	normal	normal	ADJ
dti-2192	41	44	body	body	NOUN
dti-2192	41	45	mass	mass	NOUN
dti-2192	41	46	index	index	NOUN
dti-2192	41	47	(	(	PUNCT
dti-2192	41	48	bmi	bmi	PROPN
dti-2192	41	49	)	)	PUNCT
dti-2192	41	50	but	but	CCONJ
dti-2192	41	51	with	with	ADP
dti-2192	41	52	a	a	DET
dti-2192	41	53	high	high	ADJ
dti-2192	41	54	abdominal	abdominal	ADJ
dti-2192	41	55	circumference	circumference	NOUN
dti-2192	41	56	(	(	PUNCT
dti-2192	41	57	ac)—due	ac)—due	ADJ
dti-2192	41	58	to	to	PART
dti-2192	41	59	unregulated	unregulated	ADJ
dti-2192	41	60	cytokine	cytokine	ADJ
dti-2192	41	61	secretion	secretion	NOUN
dti-2192	41	62	pathways	pathway	NOUN
dti-2192	41	63	.	.	PUNCT
dti-2192	42	1	in	in	ADP
dti-2192	42	2	addition	addition	NOUN
dti-2192	42	3	,	,	PUNCT
dti-2192	42	4	inflammation	inflammation	NOUN
dti-2192	42	5	and	and	CCONJ
dti-2192	42	6	increased	increase	VERB
dti-2192	42	7	release	release	NOUN
dti-2192	42	8	of	of	ADP
dti-2192	42	9	circulating	circulate	VERB
dti-2192	42	10	fatty	fatty	NOUN
dti-2192	42	11	acids	acid	NOUN
dti-2192	42	12	is	be	AUX
dti-2192	42	13	associated	associate	VERB
dti-2192	42	14	with	with	ADP
dti-2192	42	15	visceral	visceral	ADJ
dti-2192	42	16	fat	fat	NOUN
dti-2192	42	17	.	.	PUNCT
dti-2192	43	1	thus	thus	ADV
dti-2192	43	2	,	,	PUNCT
dti-2192	43	3	the	the	DET
dti-2192	43	4	fat	fat	ADJ
dti-2192	43	5	distribution	distribution	NOUN
dti-2192	43	6	phenotype	phenotype	NOUN
dti-2192	43	7	contributes	contribute	VERB
dti-2192	43	8	to	to	ADP
dti-2192	43	9	metabolism	metabolism	NOUN
dti-2192	43	10	,	,	PUNCT
dti-2192	43	11	leading	lead	VERB
dti-2192	43	12	to	to	ADP
dti-2192	43	13	metabolically	metabolically	ADV
dti-2192	43	14	unhealthy	unhealthy	ADJ
dti-2192	43	15	individuals	individual	NOUN
dti-2192	43	16	(	(	PUNCT
dti-2192	43	17	22	22	NUM
dti-2192	43	18	)	)	PUNCT
dti-2192	43	19	.	.	PUNCT
dti-2192	44	1	thus	thus	ADV
dti-2192	44	2	,	,	PUNCT
dti-2192	44	3	visceral	visceral	ADJ
dti-2192	44	4	obesity	obesity	NOUN
dti-2192	44	5	can	can	AUX
dti-2192	44	6	be	be	AUX
dti-2192	44	7	an	an	DET
dti-2192	44	8	important	important	ADJ
dti-2192	44	9	risk	risk	NOUN
dti-2192	44	10	factor	factor	NOUN
dti-2192	44	11	to	to	PART
dti-2192	44	12	increase	increase	VERB
dti-2192	44	13	the	the	DET
dti-2192	44	14	severity	severity	NOUN
dti-2192	44	15	of	of	ADP
dti-2192	44	16	covid-19	covid-19	PROPN
dti-2192	44	17	(	(	PUNCT
dti-2192	44	18	23	23	NUM
dti-2192	44	19	)	)	PUNCT
dti-2192	44	20	.	.	PUNCT
dti-2192	45	1	studies	study	NOUN
dti-2192	45	2	with	with	ADP
dti-2192	45	3	patients	patient	NOUN
dti-2192	45	4	affected	affect	VERB
dti-2192	45	5	by	by	ADP
dti-2192	45	6	this	this	DET
dti-2192	45	7	disease	disease	NOUN
dti-2192	45	8	in	in	ADP
dti-2192	45	9	germany	germany	PROPN
dti-2192	45	10	and	and	CCONJ
dti-2192	45	11	italy	italy	PROPN
dti-2192	45	12	have	have	AUX
dti-2192	45	13	shown	show	VERB
dti-2192	45	14	that	that	SCONJ
dti-2192	45	15	as	as	SCONJ
dti-2192	45	16	the	the	DET
dti-2192	45	17	area	area	NOUN
dti-2192	45	18	of	of	ADP
dti-2192	45	19	visceral	visceral	ADJ
dti-2192	45	20	adipose	adipose	ADJ
dti-2192	45	21	tissue	tissue	NOUN
dti-2192	45	22	increased	increase	VERB
dti-2192	45	23	,	,	PUNCT
dti-2192	45	24	there	there	PRON
dti-2192	45	25	was	be	VERB
dti-2192	45	26	a	a	DET
dti-2192	45	27	greater	great	ADJ
dti-2192	45	28	need	need	NOUN
dti-2192	45	29	for	for	ADP
dti-2192	45	30	intensive	intensive	ADJ
dti-2192	45	31	therapy	therapy	NOUN
dti-2192	45	32	,	,	PUNCT
dti-2192	45	33	regardless	regardless	ADV
dti-2192	45	34	of	of	ADP
dti-2192	45	35	other	other	ADJ
dti-2192	45	36	factors	factor	NOUN
dti-2192	45	37	,	,	PUNCT
dti-2192	45	38	such	such	ADJ
dti-2192	45	39	as	as	ADP
dti-2192	45	40	age	age	NOUN
dti-2192	45	41	,	,	PUNCT
dti-2192	45	42	sex	sex	NOUN
dti-2192	45	43	,	,	PUNCT
dti-2192	45	44	and	and	CCONJ
dti-2192	45	45	associated	associated	ADJ
dti-2192	45	46	diseases	disease	NOUN
dti-2192	45	47	(	(	PUNCT
dti-2192	45	48	24,25	24,25	NUM
dti-2192	45	49	)	)	PUNCT
dti-2192	45	50	.	.	PUNCT
dti-2192	46	1	another	another	DET
dti-2192	46	2	study	study	NOUN
dti-2192	46	3	performed	perform	VERB
dti-2192	46	4	in	in	ADP
dti-2192	46	5	china	china	PROPN
dti-2192	46	6	with	with	ADP
dti-2192	46	7	covid-19	covid-19	PROPN
dti-2192	46	8	patients	patient	NOUN
dti-2192	46	9	showed	show	VERB
dti-2192	46	10	that	that	SCONJ
dti-2192	46	11	higher	high	ADJ
dti-2192	46	12	visceral	visceral	ADJ
dti-2192	46	13	and	and	CCONJ
dti-2192	46	14	subcutaneous	subcutaneous	ADJ
dti-2192	46	15	adipose	adipose	ADJ
dti-2192	46	16	tissue	tissue	NOUN
dti-2192	46	17	were	be	AUX
dti-2192	46	18	independent	independent	ADJ
dti-2192	46	19	risk	risk	NOUN
dti-2192	46	20	factors	factor	NOUN
dti-2192	46	21	for	for	ADP
dti-2192	46	22	critical	critical	ADJ
dti-2192	46	23	illness	illness	NOUN
dti-2192	46	24	(	(	PUNCT
dti-2192	46	25	26	26	NUM
dti-2192	46	26	)	)	PUNCT
dti-2192	46	27	.	.	PUNCT
dti-2192	47	1	in	in	ADP
dti-2192	47	2	addition	addition	NOUN
dti-2192	47	3	,	,	PUNCT
dti-2192	47	4	visceral	visceral	ADJ
dti-2192	47	5	adipose	adipose	PRON
dti-2192	47	6	tissue	tissue	NOUN
dti-2192	47	7	positively	positively	ADV
dti-2192	47	8	regulates	regulate	VERB
dti-2192	47	9	the	the	DET
dti-2192	47	10	expression	expression	NOUN
dti-2192	47	11	of	of	ADP
dti-2192	47	12	plasminogen	plasminogen	NOUN
dti-2192	47	13	activator	activator	NOUN
dti-2192	47	14	inhibitor	inhibitor	NOUN
dti-2192	47	15	1	1	NUM
dti-2192	47	16	,	,	PUNCT
dti-2192	47	17	thus	thus	ADV
dti-2192	47	18	generating	generate	VERB
dti-2192	47	19	an	an	DET
dti-2192	47	20	increased	increase	VERB
dti-2192	47	21	risk	risk	NOUN
dti-2192	47	22	of	of	ADP
dti-2192	47	23	developing	develop	VERB
dti-2192	47	24	thrombosis	thrombosis	NOUN
dti-2192	47	25	in	in	ADP
dti-2192	47	26	patients	patient	NOUN
dti-2192	47	27	with	with	ADP
dti-2192	47	28	visceral	visceral	ADJ
dti-2192	47	29	obesity	obesity	NOUN
dti-2192	47	30	affected	affect	VERB
dti-2192	47	31	by	by	ADP
dti-2192	47	32	covid-19	covid-19	PROPN
dti-2192	47	33	(	(	PUNCT
dti-2192	47	34	27	27	NUM
dti-2192	47	35	)	)	PUNCT
dti-2192	47	36	.	.	PUNCT
dti-2192	48	1	thus	thus	ADV
dti-2192	48	2	,	,	PUNCT
dti-2192	48	3	understanding	understand	VERB
dti-2192	48	4	the	the	DET
dti-2192	48	5	metabolically	metabolically	ADV
dti-2192	48	6	unhealthy	unhealthy	ADJ
dti-2192	48	7	individual	individual	NOUN
dti-2192	48	8	is	be	AUX
dti-2192	48	9	essential	essential	ADJ
dti-2192	48	10	,	,	PUNCT
dti-2192	48	11	carefully	carefully	ADV
dti-2192	48	12	assessing	assess	VERB
dti-2192	48	13	the	the	DET
dti-2192	48	14	response	response	NOUN
dti-2192	48	15	to	to	ADP
dti-2192	48	16	sars	sars	PROPN
dti-2192	48	17	-	-	PUNCT
dti-2192	48	18	cov	cov	NOUN
dti-2192	48	19	vaccination	vaccination	NOUN
dti-2192	48	20	(	(	PUNCT
dti-2192	48	21	23	23	NUM
dti-2192	48	22	)	)	PUNCT
dti-2192	48	23	,	,	PUNCT
dti-2192	48	24	as	as	SCONJ
dti-2192	48	25	obesity	obesity	NOUN
dti-2192	48	26	and	and	CCONJ
dti-2192	48	27	impaired	impaired	ADJ
dti-2192	48	28	metabolic	metabolic	NOUN
dti-2192	48	29	health	health	NOUN
dti-2192	48	30	generate	generate	VERB
dti-2192	48	31	a	a	DET
dti-2192	48	32	potentially	potentially	ADV
dti-2192	48	33	reduced	reduce	VERB
dti-2192	48	34	immune	immune	ADJ
dti-2192	48	35	response	response	NOUN
dti-2192	48	36	,	,	PUNCT
dti-2192	48	37	which	which	PRON
dti-2192	48	38	can	can	AUX
dti-2192	48	39	negatively	negatively	ADV
dti-2192	48	40	affect	affect	VERB
dti-2192	48	41	the	the	DET
dti-2192	48	42	vaccine	vaccine	NOUN
dti-2192	48	43	’s	’s	PART
dti-2192	48	44	effectiveness	effectiveness	NOUN
dti-2192	48	45	(	(	PUNCT
dti-2192	48	46	28	28	NUM
dti-2192	48	47	-	-	SYM
dti-2192	48	48	31	31	NUM
dti-2192	48	49	)	)	PUNCT
dti-2192	48	50	.	.	PUNCT
dti-2192	49	1	obesity	obesity	NOUN
dti-2192	49	2	is	be	AUX
dti-2192	49	3	characterized	characterize	VERB
dti-2192	49	4	by	by	ADP
dti-2192	49	5	a	a	DET
dti-2192	49	6	state	state	NOUN
dti-2192	49	7	of	of	ADP
dti-2192	49	8	low	low	ADJ
dti-2192	49	9	-	-	PUNCT
dti-2192	49	10	grade	grade	NOUN
dti-2192	49	11	chronic	chronic	ADJ
dti-2192	49	12	inflammation	inflammation	NOUN
dti-2192	49	13	related	relate	VERB
dti-2192	49	14	to	to	ADP
dti-2192	49	15	changes	change	NOUN
dti-2192	49	16	in	in	ADP
dti-2192	49	17	immune	immune	ADJ
dti-2192	49	18	cells	cell	NOUN
dti-2192	49	19	,	,	PUNCT
dti-2192	49	20	including	include	VERB
dti-2192	49	21	the	the	DET
dti-2192	49	22	number	number	NOUN
dti-2192	49	23	and	and	CCONJ
dti-2192	49	24	types	type	NOUN
dti-2192	49	25	of	of	ADP
dti-2192	49	26	cells	cell	NOUN
dti-2192	49	27	present	present	ADJ
dti-2192	49	28	in	in	ADP
dti-2192	49	29	the	the	DET
dti-2192	49	30	inflamed	inflamed	ADJ
dti-2192	49	31	tissue	tissue	NOUN
dti-2192	49	32	.	.	PUNCT
dti-2192	50	1	at	at	ADP
dti-2192	50	2	the	the	DET
dti-2192	50	3	beginning	beginning	NOUN
dti-2192	50	4	of	of	ADP
dti-2192	50	5	weight	weight	NOUN
dti-2192	50	6	gain	gain	NOUN
dti-2192	50	7	,	,	PUNCT
dti-2192	50	8	immune	immune	ADJ
dti-2192	50	9	cells	cell	NOUN
dti-2192	50	10	infiltrate	infiltrate	VERB
dti-2192	50	11	adipose	adipose	ADJ
dti-2192	50	12	tissue	tissue	NOUN
dti-2192	50	13	,	,	PUNCT
dti-2192	50	14	contributing	contribute	VERB
dti-2192	50	15	to	to	ADP
dti-2192	50	16	persistent	persistent	ADJ
dti-2192	50	17	adipose	adipose	ADP
dti-2192	50	18	inflammation	inflammation	NOUN
dti-2192	50	19	and	and	CCONJ
dti-2192	50	20	insulin	insulin	NOUN
dti-2192	50	21	resistance	resistance	NOUN
dti-2192	50	22	.	.	PUNCT
dti-2192	51	1	macrophages	macrophage	NOUN
dti-2192	51	2	are	be	AUX
dti-2192	51	3	classified	classify	VERB
dti-2192	51	4	into	into	ADP
dti-2192	51	5	two	two	NUM
dti-2192	51	6	subtypes	subtype	NOUN
dti-2192	51	7	of	of	ADP
dti-2192	51	8	phenotypes	phenotype	NOUN
dti-2192	51	9	,	,	PUNCT
dti-2192	51	10	m1	m1	NOUN
dti-2192	51	11	proinflammatory	proinflammatory	NOUN
dti-2192	51	12	and	and	CCONJ
dti-2192	51	13	m2	m2	PROPN
dti-2192	51	14	anti	anti	ADJ
dti-2192	51	15	-	-	ADJ
dti-2192	51	16	inflammatory	inflammatory	ADJ
dti-2192	51	17	.	.	PUNCT
dti-2192	52	1	in	in	ADP
dti-2192	52	2	eutrophic	eutrophic	ADJ
dti-2192	52	3	individuals	individual	NOUN
dti-2192	52	4	,	,	PUNCT
dti-2192	52	5	the	the	DET
dti-2192	52	6	m2	m2	PROPN
dti-2192	52	7	subtype	subtype	NOUN
dti-2192	52	8	is	be	AUX
dti-2192	52	9	distributed	distribute	VERB
dti-2192	52	10	throughout	throughout	ADP
dti-2192	52	11	adipose	adipose	ADJ
dti-2192	52	12	tissue	tissue	NOUN
dti-2192	52	13	,	,	PUNCT
dti-2192	52	14	producing	produce	VERB
dti-2192	52	15	interleukin	interleukin	NOUN
dti-2192	52	16	(	(	PUNCT
dti-2192	52	17	il)-10	il)-10	PROPN
dti-2192	52	18	and	and	CCONJ
dti-2192	52	19	expressing	express	VERB
dti-2192	52	20	arginase-1	arginase-1	PROPN
dti-2192	52	21	for	for	ADP
dti-2192	52	22	collagen	collagen	NOUN
dti-2192	52	23	synthesis	synthesis	NOUN
dti-2192	52	24	,	,	PUNCT
dti-2192	52	25	which	which	PRON
dti-2192	52	26	is	be	AUX
dti-2192	52	27	important	important	ADJ
dti-2192	52	28	for	for	ADP
dti-2192	52	29	promoting	promote	VERB
dti-2192	52	30	tissue	tissue	NOUN
dti-2192	52	31	repair	repair	NOUN
dti-2192	52	32	.	.	PUNCT
dti-2192	53	1	during	during	ADP
dti-2192	53	2	the	the	DET
dti-2192	53	3	progression	progression	NOUN
dti-2192	53	4	of	of	ADP
dti-2192	53	5	weight	weight	NOUN
dti-2192	53	6	gain	gain	NOUN
dti-2192	53	7	to	to	ADP
dti-2192	53	8	obesity	obesity	NOUN
dti-2192	53	9	,	,	PUNCT
dti-2192	53	10	the	the	DET
dti-2192	53	11	m1	m1	NOUN
dti-2192	53	12	subtype	subtype	NOUN
dti-2192	53	13	becomes	become	VERB
dti-2192	53	14	dominant	dominant	ADJ
dti-2192	53	15	,	,	PUNCT
dti-2192	53	16	spreading	spread	VERB
dti-2192	53	17	inflammation	inflammation	NOUN
dti-2192	53	18	through	through	ADP
dti-2192	53	19	the	the	DET
dti-2192	53	20	production	production	NOUN
dti-2192	53	21	of	of	ADP
dti-2192	53	22	mediators	mediator	NOUN
dti-2192	53	23	,	,	PUNCT
dti-2192	53	24	such	such	ADJ
dti-2192	53	25	as	as	ADP
dti-2192	53	26	tumor	tumor	NOUN
dti-2192	53	27	necrosis	necrosis	NOUN
dti-2192	53	28	factor	factor	NOUN
dti-2192	53	29	α	α	PROPN
dti-2192	53	30	(	(	PUNCT
dti-2192	53	31	tnf	tnf	PROPN
dti-2192	53	32	-	-	PUNCT
dti-2192	53	33	α	α	NOUN
dti-2192	53	34	)	)	PUNCT
dti-2192	53	35	,	,	PUNCT
dti-2192	53	36	il-1β	il-1β	PROPN
dti-2192	53	37	,	,	PUNCT
dti-2192	53	38	monocyte	monocyte	NOUN
dti-2192	53	39	chemoattractant	chemoattractant	PROPN
dti-2192	53	40	protein-1	protein-1	PROPN
dti-2192	53	41	(	(	PUNCT
dti-2192	53	42	mcp1	mcp1	PROPN
dti-2192	53	43	)	)	PUNCT
dti-2192	53	44	,	,	PUNCT
dti-2192	53	45	plasminogen	plasminogen	NOUN
dti-2192	53	46	activator	activator	NOUN
dti-2192	53	47	inhibitor	inhibitor	NOUN
dti-2192	53	48	1	1	NUM
dti-2192	53	49	(	(	PUNCT
dti-2192	53	50	pai-1	pai-1	X
dti-2192	53	51	)	)	PUNCT
dti-2192	53	52	and	and	CCONJ
dti-2192	53	53	reactive	reactive	ADJ
dti-2192	53	54	oxygen	oxygen	NOUN
dti-2192	53	55	species	specie	NOUN
dti-2192	53	56	(	(	PUNCT
dti-2192	53	57	ros	ros	PROPN
dti-2192	53	58	)	)	PUNCT
dti-2192	53	59	.	.	PUNCT
dti-2192	54	1	as	as	ADP
dti-2192	54	2	a	a	DET
dti-2192	54	3	result	result	NOUN
dti-2192	54	4	,	,	PUNCT
dti-2192	54	5	m1	m1	NOUN
dti-2192	54	6	macrophages	macrophage	NOUN
dti-2192	54	7	interrupt	interrupt	ADJ
dti-2192	54	8	insulin	insulin	NOUN
dti-2192	54	9	sensitivity	sensitivity	NOUN
dti-2192	54	10	in	in	ADP
dti-2192	54	11	adipose	adipose	ADJ
dti-2192	54	12	tissue	tissue	NOUN
dti-2192	54	13	and	and	CCONJ
dti-2192	54	14	the	the	DET
dti-2192	54	15	liver	liver	NOUN
dti-2192	54	16	(	(	PUNCT
dti-2192	54	17	20	20	NUM
dti-2192	54	18	)	)	PUNCT
dti-2192	54	19	.	.	PUNCT
dti-2192	55	1	the	the	DET
dti-2192	55	2	hormone	hormone	NOUN
dti-2192	55	3	leptin	leptin	NOUN
dti-2192	55	4	overlaps	overlap	NOUN
dti-2192	55	5	when	when	SCONJ
dti-2192	55	6	referring	refer	VERB
dti-2192	55	7	to	to	ADP
dti-2192	55	8	the	the	DET
dti-2192	55	9	link	link	NOUN
dti-2192	55	10	between	between	ADP
dti-2192	55	11	obesity	obesity	NOUN
dti-2192	55	12	and	and	CCONJ
dti-2192	55	13	inflammation	inflammation	NOUN
dti-2192	55	14	,	,	PUNCT
dti-2192	55	15	since	since	SCONJ
dti-2192	55	16	leptin	leptin	NOUN
dti-2192	55	17	synthesis	synthesis	NOUN
dti-2192	55	18	is	be	AUX
dti-2192	55	19	directly	directly	ADV
dti-2192	55	20	proportional	proportional	ADJ
dti-2192	55	21	to	to	ADP
dti-2192	55	22	the	the	DET
dti-2192	55	23	amount	amount	NOUN
dti-2192	55	24	of	of	ADP
dti-2192	55	25	adipose	adipose	ADJ
dti-2192	55	26	tissue	tissue	NOUN
dti-2192	55	27	,	,	PUNCT
dti-2192	55	28	and	and	CCONJ
dti-2192	55	29	inflammatory	inflammatory	ADJ
dti-2192	55	30	cytokines	cytokine	NOUN
dti-2192	55	31	stimulate	stimulate	VERB
dti-2192	55	32	this	this	DET
dti-2192	55	33	synthesis	synthesis	NOUN
dti-2192	55	34	.	.	PUNCT
dti-2192	56	1	these	these	DET
dti-2192	56	2	inflammatory	inflammatory	ADJ
dti-2192	56	3	cytokines	cytokine	NOUN
dti-2192	56	4	,	,	PUNCT
dti-2192	56	5	such	such	ADJ
dti-2192	56	6	as	as	ADP
dti-2192	56	7	tnf	tnf	PROPN
dti-2192	56	8	-	-	PUNCT
dti-2192	56	9	α	α	PROPN
dti-2192	56	10	,	,	PUNCT
dti-2192	56	11	il-1β	il-1β	PROPN
dti-2192	56	12	,	,	PUNCT
dti-2192	56	13	il-6	il-6	NOUN
dti-2192	56	14	,	,	PUNCT
dti-2192	56	15	and	and	CCONJ
dti-2192	56	16	interferon	interferon	ADJ
dti-2192	56	17	gamma	gamma	NOUN
dti-2192	56	18	(	(	PUNCT
dti-2192	56	19	ifn	ifn	PROPN
dti-2192	56	20	-	-	PUNCT
dti-2192	56	21	γ	γ	NOUN
dti-2192	56	22	)	)	PUNCT
dti-2192	56	23	,	,	PUNCT
dti-2192	56	24	coagulation	coagulation	NOUN
dti-2192	56	25	factors	factor	NOUN
dti-2192	56	26	(	(	PUNCT
dti-2192	56	27	fibrinogen	fibrinogen	NOUN
dti-2192	56	28	and	and	CCONJ
dti-2192	56	29	pai-1	pai-1	NUM
dti-2192	56	30	)	)	PUNCT
dti-2192	56	31	,	,	PUNCT
dti-2192	56	32	acute	acute	ADJ
dti-2192	56	33	-	-	PUNCT
dti-2192	56	34	phase	phase	NOUN
dti-2192	56	35	protein	protein	NOUN
dti-2192	56	36	(	(	PUNCT
dti-2192	56	37	c	c	NOUN
dti-2192	56	38	-	-	ADJ
dti-2192	56	39	reactive	reactive	ADJ
dti-2192	56	40	protein	protein	NOUN
dti-2192	56	41	and	and	CCONJ
dti-2192	56	42	amyloid	amyloid	NOUN
dti-2192	56	43	serum	serum	VERB
dti-2192	56	44	a	a	DET
dti-2192	56	45	[	[	X
dti-2192	56	46	saa	saa	X
dti-2192	56	47	]	]	PUNCT
dti-2192	56	48	)	)	PUNCT
dti-2192	56	49	,	,	PUNCT
dti-2192	56	50	white	white	ADJ
dti-2192	56	51	blood	blood	NOUN
dti-2192	56	52	cell	cell	NOUN
dti-2192	56	53	count	count	NOUN
dti-2192	56	54	,	,	PUNCT
dti-2192	56	55	and	and	CCONJ
dti-2192	56	56	chemokines	chemokine	NOUN
dti-2192	56	57	are	be	AUX
dti-2192	56	58	markers	marker	NOUN
dti-2192	56	59	of	of	ADP
dti-2192	56	60	inflammation	inflammation	NOUN
dti-2192	56	61	.	.	PUNCT
dti-2192	57	1	in	in	ADP
dti-2192	57	2	patients	patient	NOUN
dti-2192	57	3	with	with	ADP
dti-2192	57	4	obesity	obesity	NOUN
dti-2192	57	5	,	,	PUNCT
dti-2192	57	6	these	these	DET
dti-2192	57	7	markers	marker	NOUN
dti-2192	57	8	are	be	AUX
dti-2192	57	9	commonly	commonly	ADV
dti-2192	57	10	elevated	elevate	VERB
dti-2192	57	11	,	,	PUNCT
dti-2192	57	12	and	and	CCONJ
dti-2192	57	13	with	with	ADP
dti-2192	57	14	the	the	DET
dti-2192	57	15	reduction	reduction	NOUN
dti-2192	57	16	of	of	ADP
dti-2192	57	17	excess	excess	ADJ
dti-2192	57	18	weight	weight	NOUN
dti-2192	57	19	,	,	PUNCT
dti-2192	57	20	there	there	PRON
dti-2192	57	21	is	be	VERB
dti-2192	57	22	a	a	DET
dti-2192	57	23	reduction	reduction	NOUN
dti-2192	57	24	in	in	ADP
dti-2192	57	25	their	their	PRON
dti-2192	57	26	plasma	plasma	NOUN
dti-2192	57	27	concentrations	concentration	NOUN
dti-2192	57	28	(	(	PUNCT
dti-2192	57	29	32	32	NUM
dti-2192	57	30	)	)	PUNCT
dti-2192	57	31	.	.	PUNCT
dti-2192	58	1	there	there	PRON
dti-2192	58	2	are	be	VERB
dti-2192	58	3	also	also	ADV
dti-2192	58	4	anti	anti	ADJ
dti-2192	58	5	-	-	ADJ
dti-2192	58	6	inflammatory	inflammatory	ADJ
dti-2192	58	7	adipokines	adipokine	NOUN
dti-2192	58	8	,	,	PUNCT
dti-2192	58	9	such	such	ADJ
dti-2192	58	10	as	as	ADP
dti-2192	58	11	il-4	il-4	NOUN
dti-2192	58	12	,	,	PUNCT
dti-2192	58	13	il-5	il-5	NOUN
dti-2192	58	14	,	,	PUNCT
dti-2192	58	15	and	and	CCONJ
dti-2192	58	16	il-10	il-10	PRON
dti-2192	58	17	,	,	PUNCT
dti-2192	58	18	which	which	PRON
dti-2192	58	19	can	can	AUX
dti-2192	58	20	be	be	AUX
dti-2192	58	21	observed	observe	VERB
dti-2192	58	22	in	in	ADP
dti-2192	58	23	obesity	obesity	NOUN
dti-2192	58	24	at	at	ADP
dti-2192	58	25	low	low	ADJ
dti-2192	58	26	concentrations	concentration	NOUN
dti-2192	58	27	.	.	PUNCT
dti-2192	59	1	thus	thus	ADV
dti-2192	59	2	,	,	PUNCT
dti-2192	59	3	an	an	DET
dti-2192	59	4	imbalance	imbalance	NOUN
dti-2192	59	5	between	between	ADP
dti-2192	59	6	these	these	DET
dti-2192	59	7	antiand	antiand	CCONJ
dti-2192	59	8	inflammatory	inflammatory	ADJ
dti-2192	59	9	cytokines	cytokine	NOUN
dti-2192	59	10	can	can	AUX
dti-2192	59	11	induce	induce	VERB
dti-2192	59	12	the	the	DET
dti-2192	59	13	inflammatory	inflammatory	ADJ
dti-2192	59	14	response	response	NOUN
dti-2192	59	15	(	(	PUNCT
dti-2192	59	16	33	33	NUM
dti-2192	59	17	)	)	PUNCT
dti-2192	59	18	.	.	PUNCT
dti-2192	60	1	considering	consider	VERB
dti-2192	60	2	that	that	SCONJ
dti-2192	60	3	obesity	obesity	NOUN
dti-2192	60	4	negatively	negatively	ADV
dti-2192	60	5	affects	affect	VERB
dti-2192	60	6	the	the	DET
dti-2192	60	7	immune	immune	ADJ
dti-2192	60	8	system	system	NOUN
dti-2192	60	9	,	,	PUNCT
dti-2192	60	10	there	there	PRON
dti-2192	60	11	is	be	VERB
dti-2192	60	12	,	,	PUNCT
dti-2192	60	13	therefore	therefore	ADV
dti-2192	60	14	,	,	PUNCT
dti-2192	60	15	a	a	DET
dti-2192	60	16	clear	clear	ADJ
dti-2192	60	17	relationship	relationship	NOUN
dti-2192	60	18	with	with	ADP
dti-2192	60	19	the	the	DET
dti-2192	60	20	higher	high	ADJ
dti-2192	60	21	susceptibility	susceptibility	NOUN
dti-2192	60	22	to	to	ADP
dti-2192	60	23	the	the	DET
dti-2192	60	24	more	more	ADV
dti-2192	60	25	severe	severe	ADJ
dti-2192	60	26	covid-19	covid-19	PROPN
dti-2192	60	27	.	.	PUNCT
dti-2192	61	1	this	this	DET
dti-2192	61	2	close	close	ADJ
dti-2192	61	3	relationship	relationship	NOUN
dti-2192	61	4	occurs	occur	VERB
dti-2192	61	5	due	due	ADJ
dti-2192	61	6	to	to	ADP
dti-2192	61	7	the	the	DET
dti-2192	61	8	increased	increase	VERB
dti-2192	61	9	release	release	NOUN
dti-2192	61	10	of	of	ADP
dti-2192	61	11	inflammatory	inflammatory	ADJ
dti-2192	61	12	cytokines	cytokine	NOUN
dti-2192	61	13	by	by	ADP
dti-2192	61	14	disrupting	disrupt	VERB
dti-2192	61	15	the	the	DET
dti-2192	61	16	integrity	integrity	NOUN
dti-2192	61	17	of	of	ADP
dti-2192	61	18	tissues	tissue	NOUN
dti-2192	61	19	(	(	PUNCT
dti-2192	61	20	adipose	adipose	X
dti-2192	61	21	and	and	CCONJ
dti-2192	61	22	lymphoid	lymphoid	ADJ
dti-2192	61	23	tissue	tissue	NOUN
dti-2192	61	24	,	,	PUNCT
dti-2192	61	25	intestines	intestine	NOUN
dti-2192	61	26	,	,	PUNCT
dti-2192	61	27	and	and	CCONJ
dti-2192	61	28	lungs	lung	NOUN
dti-2192	61	29	)	)	PUNCT
dti-2192	61	30	,	,	PUNCT
dti-2192	61	31	which	which	PRON
dti-2192	61	32	alters	alter	VERB
dti-2192	61	33	the	the	DET
dti-2192	61	34	activation	activation	NOUN
dti-2192	61	35	of	of	ADP
dti-2192	61	36	leukocytes	leukocyte	NOUN
dti-2192	61	37	,	,	PUNCT
dti-2192	61	38	impairing	impair	VERB
dti-2192	61	39	the	the	DET
dti-2192	61	40	action	action	NOUN
dti-2192	61	41	of	of	ADP
dti-2192	61	42	the	the	DET
dti-2192	61	43	immune	immune	ADJ
dti-2192	61	44	system	system	NOUN
dti-2192	61	45	.	.	PUNCT
dti-2192	62	1	as	as	ADP
dti-2192	62	2	a	a	DET
dti-2192	62	3	result	result	NOUN
dti-2192	62	4	,	,	PUNCT
dti-2192	62	5	there	there	PRON
dti-2192	62	6	is	be	VERB
dti-2192	62	7	a	a	DET
dti-2192	62	8	direct	direct	ADJ
dti-2192	62	9	impact	impact	NOUN
dti-2192	62	10	on	on	ADP
dti-2192	62	11	the	the	DET
dti-2192	62	12	healing	healing	NOUN
dti-2192	62	13	process	process	NOUN
dti-2192	62	14	,	,	PUNCT
dti-2192	62	15	which	which	PRON
dti-2192	62	16	prolongs	prolong	VERB
dti-2192	62	17	recovery	recovery	NOUN
dti-2192	62	18	and	and	CCONJ
dti-2192	62	19	increases	increase	VERB
dti-2192	62	20	the	the	DET
dti-2192	62	21	risk	risk	NOUN
dti-2192	62	22	of	of	ADP
dti-2192	62	23	evolution	evolution	NOUN
dti-2192	62	24	from	from	ADP
dti-2192	62	25	respiratory	respiratory	ADJ
dti-2192	62	26	infection	infection	NOUN
dti-2192	62	27	to	to	ADP
dti-2192	62	28	severe	severe	ADJ
dti-2192	62	29	diseases	disease	NOUN
dti-2192	62	30	with	with	ADP
dti-2192	62	31	a	a	DET
dti-2192	62	32	high	high	ADJ
dti-2192	62	33	risk	risk	NOUN
dti-2192	62	34	of	of	ADP
dti-2192	62	35	death	death	NOUN
dti-2192	62	36	(	(	PUNCT
dti-2192	62	37	34	34	NUM
dti-2192	62	38	)	)	PUNCT
dti-2192	62	39	.	.	PUNCT
dti-2192	63	1	it	it	PRON
dti-2192	63	2	is	be	AUX
dti-2192	63	3	important	important	ADJ
dti-2192	63	4	to	to	PART
dti-2192	63	5	highlight	highlight	VERB
dti-2192	63	6	that	that	SCONJ
dti-2192	63	7	sars	sar	NOUN
dti-2192	63	8	-	-	PUNCT
dti-2192	63	9	cov	cov	PROPN
dti-2192	63	10	is	be	AUX
dti-2192	63	11	responsible	responsible	ADJ
dti-2192	63	12	for	for	ADP
dti-2192	63	13	coding	code	VERB
dti-2192	63	14	3c	3c	NUM
dti-2192	63	15	-	-	PUNCT
dti-2192	63	16	like	like	ADJ
dti-2192	63	17	protease	protease	NOUN
dti-2192	63	18	(	(	PUNCT
dti-2192	63	19	3cl	3cl	ADJ
dti-2192	63	20	pro	pro	NOUN
dti-2192	63	21	)	)	PUNCT
dti-2192	63	22	,	,	PUNCT
dti-2192	63	23	a	a	DET
dti-2192	63	24	cysteine	cysteine	NOUN
dti-2192	63	25	protease	protease	NOUN
dti-2192	63	26	(	(	PUNCT
dti-2192	63	27	35	35	NUM
dti-2192	63	28	)	)	PUNCT
dti-2192	63	29	,	,	PUNCT
dti-2192	63	30	formally	formally	ADV
dti-2192	63	31	known	know	VERB
dti-2192	63	32	as	as	ADP
dti-2192	63	33	c30	c30	PROPN
dti-2192	63	34	endopeptidase	endopeptidase	NOUN
dti-2192	63	35	that	that	PRON
dti-2192	63	36	is	be	AUX
dti-2192	63	37	chymotrypsinlike	chymotrypsinlike	ADJ
dti-2192	63	38	(	(	PUNCT
dti-2192	63	39	36	36	NUM
dti-2192	63	40	)	)	PUNCT
dti-2192	63	41	.	.	PUNCT
dti-2192	64	1	it	it	PRON
dti-2192	64	2	is	be	AUX
dti-2192	64	3	considered	consider	VERB
dti-2192	64	4	a	a	DET
dti-2192	64	5	key	key	ADJ
dti-2192	64	6	component	component	NOUN
dti-2192	64	7	in	in	ADP
dti-2192	64	8	polyprotein	polyprotein	ADJ
dti-2192	64	9	processing	processing	NOUN
dti-2192	64	10	(	(	PUNCT
dti-2192	64	11	37	37	NUM
dti-2192	64	12	)	)	PUNCT
dti-2192	64	13	,	,	PUNCT
dti-2192	64	14	which	which	PRON
dti-2192	64	15	synthesizes	synthesize	VERB
dti-2192	64	16	nonstructural	nonstructural	ADJ
dti-2192	64	17	proteins	protein	NOUN
dti-2192	64	18	and	and	CCONJ
dti-2192	64	19	structural	structural	ADJ
dti-2192	64	20	proteins	protein	NOUN
dti-2192	64	21	,	,	PUNCT
dti-2192	64	22	such	such	ADJ
dti-2192	64	23	as	as	ADP
dti-2192	64	24	spike	spike	NOUN
dti-2192	64	25	(	(	PUNCT
dti-2192	64	26	s	s	NOUN
dti-2192	64	27	)	)	PUNCT
dti-2192	64	28	,	,	PUNCT
dti-2192	64	29	envelope	envelope	NOUN
dti-2192	64	30	(	(	PUNCT
dti-2192	64	31	e	e	NOUN
dti-2192	64	32	)	)	PUNCT
dti-2192	64	33	,	,	PUNCT
dti-2192	64	34	membrane	membrane	NOUN
dti-2192	64	35	(	(	PUNCT
dti-2192	64	36	m	m	NOUN
dti-2192	64	37	)	)	PUNCT
dti-2192	64	38	,	,	PUNCT
dti-2192	64	39	and	and	CCONJ
dti-2192	64	40	nucleocapsid	nucleocapsid	ADJ
dti-2192	64	41	(	(	PUNCT
dti-2192	64	42	n	n	CCONJ
dti-2192	64	43	)	)	PUNCT
dti-2192	64	44	proteins	protein	NOUN
dti-2192	64	45	(	(	PUNCT
dti-2192	64	46	38	38	NUM
dti-2192	64	47	)	)	PUNCT
dti-2192	64	48	.	.	PUNCT
dti-2192	65	1	thus	thus	ADV
dti-2192	65	2	,	,	PUNCT
dti-2192	65	3	this	this	DET
dti-2192	65	4	protease	protease	NOUN
dti-2192	65	5	plays	play	VERB
dti-2192	65	6	an	an	DET
dti-2192	65	7	important	important	ADJ
dti-2192	65	8	role	role	NOUN
dti-2192	65	9	in	in	ADP
dti-2192	65	10	the	the	DET
dti-2192	65	11	replication	replication	NOUN
dti-2192	65	12	and	and	CCONJ
dti-2192	65	13	transcription	transcription	NOUN
dti-2192	65	14	of	of	ADP
dti-2192	65	15	viral	viral	ADJ
dti-2192	65	16	ribonucleic	ribonucleic	ADJ
dti-2192	65	17	acid	acid	NOUN
dti-2192	65	18	(	(	PUNCT
dti-2192	65	19	rna	rna	PROPN
dti-2192	65	20	)	)	PUNCT
dti-2192	65	21	(	(	PUNCT
dti-2192	65	22	39	39	NUM
dti-2192	65	23	)	)	PUNCT
dti-2192	65	24	.	.	PUNCT
dti-2192	66	1	recently	recently	ADV
dti-2192	66	2	,	,	PUNCT
dti-2192	66	3	hoffmann	hoffmann	PROPN
dti-2192	66	4	et	et	PROPN
dti-2192	66	5	al	al	PROPN
dti-2192	66	6	(	(	PUNCT
dti-2192	66	7	40	40	NUM
dti-2192	66	8	)	)	PUNCT
dti-2192	66	9	demonstrated	demonstrate	VERB
dti-2192	66	10	that	that	SCONJ
dti-2192	66	11	the	the	DET
dti-2192	66	12	new	new	ADJ
dti-2192	66	13	coronavirus	coronavirus	NOUN
dti-2192	66	14	enters	enter	VERB
dti-2192	66	15	human	human	ADJ
dti-2192	66	16	cells	cell	NOUN
dti-2192	66	17	through	through	ADP
dti-2192	66	18	glycoprotein	glycoprotein	PROPN
dti-2192	66	19	s	s	PROPN
dti-2192	66	20	,	,	PUNCT
dti-2192	66	21	found	find	VERB
dti-2192	66	22	on	on	ADP
dti-2192	66	23	the	the	DET
dti-2192	66	24	surface	surface	NOUN
dti-2192	66	25	of	of	ADP
dti-2192	66	26	the	the	DET
dti-2192	66	27	virus	virus	NOUN
dti-2192	66	28	.	.	PUNCT
dti-2192	67	1	this	this	DET
dti-2192	67	2	glycoprotein	glycoprotein	NOUN
dti-2192	67	3	can	can	AUX
dti-2192	67	4	bind	bind	VERB
dti-2192	67	5	to	to	ADP
dti-2192	67	6	the	the	DET
dti-2192	67	7	angiotensin	angiotensin	NOUN
dti-2192	67	8	-	-	PUNCT
dti-2192	67	9	converting	convert	VERB
dti-2192	67	10	enzyme	enzyme	NOUN
dti-2192	67	11	2	2	NUM
dti-2192	67	12	(	(	PUNCT
dti-2192	67	13	ace-2	ace-2	NUM
dti-2192	67	14	)	)	PUNCT
dti-2192	67	15	located	locate	VERB
dti-2192	67	16	in	in	ADP
dti-2192	67	17	human	human	ADJ
dti-2192	67	18	cells	cell	NOUN
dti-2192	67	19	.	.	PUNCT
dti-2192	68	1	ace-2	ace-2	X
dti-2192	68	2	receptors	receptor	NOUN
dti-2192	68	3	are	be	AUX
dti-2192	68	4	expressed	express	VERB
dti-2192	68	5	in	in	ADP
dti-2192	68	6	the	the	DET
dti-2192	68	7	intestine	intestine	NOUN
dti-2192	68	8	,	,	PUNCT
dti-2192	68	9	kidneys	kidney	NOUN
dti-2192	68	10	,	,	PUNCT
dti-2192	68	11	lungs	lung	NOUN
dti-2192	68	12	,	,	PUNCT
dti-2192	68	13	and	and	CCONJ
dti-2192	68	14	blood	blood	NOUN
dti-2192	68	15	vessels	vessel	NOUN
dti-2192	68	16	,	,	PUNCT
dti-2192	68	17	becoming	become	VERB
dti-2192	68	18	targets	target	NOUN
dti-2192	68	19	for	for	ADP
dti-2192	68	20	sars	sar	NOUN
dti-2192	68	21	-	-	PUNCT
dti-2192	68	22	cov-2	cov-2	NOUN
dti-2192	68	23	infection	infection	NOUN
dti-2192	68	24	.	.	PUNCT
dti-2192	69	1	hoffmann	hoffmann	PROPN
dti-2192	69	2	et	et	PROPN
dti-2192	69	3	al	al	PROPN
dti-2192	69	4	(	(	PUNCT
dti-2192	69	5	40	40	NUM
dti-2192	69	6	)	)	PUNCT
dti-2192	69	7	also	also	ADV
dti-2192	69	8	morais	morais	PROPN
dti-2192	69	9	et	et	PROPN
dti-2192	69	10	al	al	PROPN
dti-2192	69	11	drug	drug	PROPN
dti-2192	69	12	target	target	NOUN
dti-2192	69	13	insights	insight	NOUN
dti-2192	69	14	2021	2021	NUM
dti-2192	69	15	;	;	PUNCT
dti-2192	69	16	15	15	NUM
dti-2192	69	17	:	:	SYM
dti-2192	69	18	7	7	NUM
dti-2192	69	19	©	©	PROPN
dti-2192	69	20	2021	2021	NUM
dti-2192	69	21	the	the	DET
dti-2192	69	22	authors	author	NOUN
dti-2192	69	23	.	.	PUNCT
dti-2192	70	1	published	publish	VERB
dti-2192	70	2	by	by	ADP
dti-2192	70	3	aboutscience	aboutscience	NOUN
dti-2192	70	4	www.aboutscience.eu	www.aboutscience.eu	NOUN
dti-2192	70	5	observed	observe	VERB
dti-2192	70	6	that	that	SCONJ
dti-2192	70	7	the	the	DET
dti-2192	70	8	cellular	cellular	ADJ
dti-2192	70	9	transmembrane	transmembrane	ADJ
dti-2192	70	10	serine	serine	NOUN
dti-2192	70	11	protease	protease	NOUN
dti-2192	70	12	2	2	NUM
dti-2192	70	13	(	(	PUNCT
dti-2192	70	14	tmprss2	tmprss2	ADV
dti-2192	70	15	)	)	PUNCT
dti-2192	70	16	is	be	AUX
dti-2192	70	17	needed	need	VERB
dti-2192	70	18	for	for	ADP
dti-2192	70	19	sars	sar	NOUN
dti-2192	70	20	-	-	PUNCT
dti-2192	70	21	cov-2	cov-2	NOUN
dti-2192	70	22	entrance	entrance	NOUN
dti-2192	70	23	in	in	ADP
dti-2192	70	24	host	host	NOUN
dti-2192	70	25	cells	cell	NOUN
dti-2192	70	26	.	.	PUNCT
dti-2192	71	1	xu	xu	PROPN
dti-2192	71	2	et	et	PROPN
dti-2192	71	3	al	al	PROPN
dti-2192	71	4	(	(	PUNCT
dti-2192	71	5	41	41	NUM
dti-2192	71	6	)	)	PUNCT
dti-2192	71	7	investigated	investigate	VERB
dti-2192	71	8	the	the	DET
dti-2192	71	9	possible	possible	ADJ
dti-2192	71	10	routes	route	NOUN
dti-2192	71	11	of	of	ADP
dti-2192	71	12	sars	sar	NOUN
dti-2192	71	13	-	-	PUNCT
dti-2192	71	14	cov-2	cov-2	PART
dti-2192	71	15	infection	infection	NOUN
dti-2192	71	16	in	in	ADP
dti-2192	71	17	the	the	DET
dti-2192	71	18	oral	oral	ADJ
dti-2192	71	19	cavity	cavity	NOUN
dti-2192	71	20	mucosa	mucosa	NOUN
dti-2192	71	21	,	,	PUNCT
dti-2192	71	22	exploring	explore	VERB
dti-2192	71	23	the	the	DET
dti-2192	71	24	expression	expression	NOUN
dti-2192	71	25	of	of	ADP
dti-2192	71	26	ace-2	ace-2	ADJ
dti-2192	71	27	and	and	CCONJ
dti-2192	71	28	the	the	DET
dti-2192	71	29	proportion	proportion	NOUN
dti-2192	71	30	and	and	CCONJ
dti-2192	71	31	composition	composition	NOUN
dti-2192	71	32	of	of	ADP
dti-2192	71	33	the	the	DET
dti-2192	71	34	cells	cell	NOUN
dti-2192	71	35	responsible	responsible	ADJ
dti-2192	71	36	for	for	ADP
dti-2192	71	37	this	this	DET
dti-2192	71	38	function	function	NOUN
dti-2192	71	39	based	base	VERB
dti-2192	71	40	on	on	ADP
dti-2192	71	41	rna	rna	NOUN
dti-2192	71	42	-	-	PUNCT
dti-2192	71	43	seq	seq	NOUN
dti-2192	71	44	profiles	profile	NOUN
dti-2192	71	45	and	and	CCONJ
dti-2192	71	46	cell	cell	NOUN
dti-2192	71	47	transcript	transcript	NOUN
dti-2192	71	48	-	-	PUNCT
dti-2192	71	49	independent	independent	ADJ
dti-2192	71	50	data	datum	NOUN
dti-2192	71	51	.	.	PUNCT
dti-2192	72	1	the	the	DET
dti-2192	72	2	results	result	NOUN
dti-2192	72	3	showed	show	VERB
dti-2192	72	4	that	that	SCONJ
dti-2192	72	5	ace-2	ace-2	PUNCT
dti-2192	72	6	could	could	AUX
dti-2192	72	7	be	be	AUX
dti-2192	72	8	expressed	express	VERB
dti-2192	72	9	in	in	ADP
dti-2192	72	10	the	the	DET
dti-2192	72	11	epithelial	epithelial	ADJ
dti-2192	72	12	cells	cell	NOUN
dti-2192	72	13	of	of	ADP
dti-2192	72	14	the	the	DET
dti-2192	72	15	oral	oral	ADJ
dti-2192	72	16	cavity	cavity	NOUN
dti-2192	72	17	,	,	PUNCT
dti-2192	72	18	mainly	mainly	ADV
dti-2192	72	19	in	in	ADP
dti-2192	72	20	the	the	DET
dti-2192	72	21	tongue	tongue	NOUN
dti-2192	72	22	,	,	PUNCT
dti-2192	72	23	oral	oral	ADJ
dti-2192	72	24	and	and	CCONJ
dti-2192	72	25	gingival	gingival	NOUN
dti-2192	72	26	tissues	tissue	NOUN
dti-2192	72	27	,	,	PUNCT
dti-2192	72	28	indicating	indicate	VERB
dti-2192	72	29	that	that	SCONJ
dti-2192	72	30	the	the	DET
dti-2192	72	31	oral	oral	ADJ
dti-2192	72	32	cavity	cavity	NOUN
dti-2192	72	33	mucosa	mucosa	NOUN
dti-2192	72	34	can	can	AUX
dti-2192	72	35	be	be	AUX
dti-2192	72	36	a	a	DET
dti-2192	72	37	potential	potential	ADJ
dti-2192	72	38	route	route	NOUN
dti-2192	72	39	for	for	ADP
dti-2192	72	40	infection	infection	NOUN
dti-2192	72	41	.	.	PUNCT
dti-2192	73	1	in	in	ADP
dti-2192	73	2	the	the	DET
dti-2192	73	3	respiratory	respiratory	ADJ
dti-2192	73	4	system	system	NOUN
dti-2192	73	5	,	,	PUNCT
dti-2192	73	6	ace-2	ace-2	NUM
dti-2192	73	7	hydrolyzes	hydrolyze	VERB
dti-2192	73	8	angiotensin	angiotensin	PROPN
dti-2192	73	9	ii	ii	PROPN
dti-2192	73	10	to	to	PART
dti-2192	73	11	angiotensin	angiotensin	VERB
dti-2192	73	12	1	1	NUM
dti-2192	73	13	-	-	SYM
dti-2192	73	14	7	7	NUM
dti-2192	73	15	,	,	PUNCT
dti-2192	73	16	with	with	ADP
dti-2192	73	17	an	an	DET
dti-2192	73	18	essential	essential	ADJ
dti-2192	73	19	role	role	NOUN
dti-2192	73	20	in	in	ADP
dti-2192	73	21	regulating	regulate	VERB
dti-2192	73	22	the	the	DET
dti-2192	73	23	system	system	NOUN
dti-2192	73	24	.	.	PUNCT
dti-2192	74	1	when	when	SCONJ
dti-2192	74	2	ace-1	ace-1	PUNCT
dti-2192	74	3	activity	activity	NOUN
dti-2192	74	4	is	be	AUX
dti-2192	74	5	increased	increase	VERB
dti-2192	74	6	and	and	CCONJ
dti-2192	74	7	ace-2	ace-2	ADV
dti-2192	74	8	is	be	AUX
dti-2192	74	9	inhibited	inhibit	VERB
dti-2192	74	10	,	,	PUNCT
dti-2192	74	11	intact	intact	ADJ
dti-2192	74	12	angiotensin	angiotensin	NOUN
dti-2192	74	13	ii	ii	PROPN
dti-2192	74	14	acts	act	VERB
dti-2192	74	15	through	through	ADP
dti-2192	74	16	the	the	DET
dti-2192	74	17	angiotensin	angiotensin	NOUN
dti-2192	74	18	1	1	NUM
dti-2192	74	19	(	(	PUNCT
dti-2192	74	20	at1	at1	PROPN
dti-2192	74	21	)	)	PUNCT
dti-2192	74	22	or	or	CCONJ
dti-2192	74	23	2	2	NUM
dti-2192	74	24	(	(	PUNCT
dti-2192	74	25	at2	at2	NOUN
dti-2192	74	26	)	)	PUNCT
dti-2192	74	27	receptor	receptor	NOUN
dti-2192	74	28	to	to	PART
dti-2192	74	29	exert	exert	VERB
dti-2192	74	30	proinflammatory	proinflammatory	ADJ
dti-2192	74	31	responses	response	NOUN
dti-2192	74	32	and	and	CCONJ
dti-2192	74	33	stimulate	stimulate	VERB
dti-2192	74	34	aldosterone	aldosterone	NOUN
dti-2192	74	35	secretion	secretion	NOUN
dti-2192	74	36	.	.	PUNCT
dti-2192	75	1	as	as	ADP
dti-2192	75	2	a	a	DET
dti-2192	75	3	result	result	NOUN
dti-2192	75	4	,	,	PUNCT
dti-2192	75	5	these	these	DET
dti-2192	75	6	effects	effect	NOUN
dti-2192	75	7	increase	increase	VERB
dti-2192	75	8	blood	blood	NOUN
dti-2192	75	9	pressure	pressure	NOUN
dti-2192	75	10	and	and	CCONJ
dti-2192	75	11	potentially	potentially	ADV
dti-2192	75	12	cause	cause	VERB
dti-2192	75	13	hypokalemia	hypokalemia	NOUN
dti-2192	75	14	,	,	PUNCT
dti-2192	75	15	in	in	ADP
dti-2192	75	16	addition	addition	NOUN
dti-2192	75	17	to	to	ADP
dti-2192	75	18	intensifying	intensify	VERB
dti-2192	75	19	local	local	ADJ
dti-2192	75	20	vascular	vascular	ADJ
dti-2192	75	21	permeability	permeability	NOUN
dti-2192	75	22	,	,	PUNCT
dti-2192	75	23	increasing	increase	VERB
dti-2192	75	24	the	the	DET
dti-2192	75	25	risk	risk	NOUN
dti-2192	75	26	of	of	ADP
dti-2192	75	27	respiratory	respiratory	ADJ
dti-2192	75	28	distress	distress	NOUN
dti-2192	75	29	syndrome	syndrome	NOUN
dti-2192	75	30	.	.	PUNCT
dti-2192	76	1	on	on	ADP
dti-2192	76	2	the	the	DET
dti-2192	76	3	other	other	ADJ
dti-2192	76	4	hand	hand	NOUN
dti-2192	76	5	,	,	PUNCT
dti-2192	76	6	angiotensin	angiotensin	NOUN
dti-2192	76	7	1	1	NUM
dti-2192	76	8	-	-	SYM
dti-2192	76	9	7	7	NUM
dti-2192	76	10	acts	act	NOUN
dti-2192	76	11	on	on	ADP
dti-2192	76	12	the	the	DET
dti-2192	76	13	receptor	receptor	NOUN
dti-2192	76	14	pathway	pathway	NOUN
dti-2192	76	15	,	,	PUNCT
dti-2192	76	16	leading	lead	VERB
dti-2192	76	17	to	to	ADP
dti-2192	76	18	antiinflammatory	antiinflammatory	NOUN
dti-2192	76	19	and	and	CCONJ
dti-2192	76	20	antifibrotic	antifibrotic	ADJ
dti-2192	76	21	responses	response	NOUN
dti-2192	76	22	that	that	PRON
dti-2192	76	23	would	would	AUX
dti-2192	76	24	be	be	AUX
dti-2192	76	25	favorable	favorable	ADJ
dti-2192	76	26	to	to	ADP
dti-2192	76	27	the	the	DET
dti-2192	76	28	recovery	recovery	NOUN
dti-2192	76	29	of	of	ADP
dti-2192	76	30	patients	patient	NOUN
dti-2192	76	31	with	with	ADP
dti-2192	76	32	covid-19	covid-19	PROPN
dti-2192	76	33	(	(	PUNCT
dti-2192	76	34	42	42	NUM
dti-2192	76	35	)	)	PUNCT
dti-2192	76	36	.	.	PUNCT
dti-2192	77	1	studies	study	NOUN
dti-2192	77	2	also	also	ADV
dti-2192	77	3	describe	describe	VERB
dti-2192	77	4	the	the	DET
dti-2192	77	5	importance	importance	NOUN
dti-2192	77	6	of	of	ADP
dti-2192	77	7	the	the	DET
dti-2192	77	8	renin	renin	ADJ
dti-2192	77	9	-	-	PUNCT
dti-2192	77	10	angiotensin	angiotensin	NOUN
dti-2192	77	11	system	system	NOUN
dti-2192	77	12	(	(	PUNCT
dti-2192	77	13	ras	ras	NOUN
dti-2192	77	14	)	)	PUNCT
dti-2192	77	15	in	in	ADP
dti-2192	77	16	the	the	DET
dti-2192	77	17	regulation	regulation	NOUN
dti-2192	77	18	of	of	ADP
dti-2192	77	19	metabolism	metabolism	NOUN
dti-2192	77	20	and	and	CCONJ
dti-2192	77	21	the	the	DET
dti-2192	77	22	development	development	NOUN
dti-2192	77	23	of	of	ADP
dti-2192	77	24	cardiovascular	cardiovascular	ADJ
dti-2192	77	25	and	and	CCONJ
dti-2192	77	26	inflammatory	inflammatory	ADJ
dti-2192	77	27	diseases	disease	NOUN
dti-2192	77	28	(	(	PUNCT
dti-2192	77	29	43	43	NUM
dti-2192	77	30	-	-	SYM
dti-2192	77	31	45	45	NUM
dti-2192	77	32	)	)	PUNCT
dti-2192	77	33	.	.	PUNCT
dti-2192	78	1	this	this	DET
dti-2192	78	2	system	system	NOUN
dti-2192	78	3	also	also	ADV
dti-2192	78	4	modulates	modulate	VERB
dti-2192	78	5	the	the	DET
dti-2192	78	6	endocrine	endocrine	NOUN
dti-2192	78	7	and	and	CCONJ
dti-2192	78	8	metabolic	metabolic	NOUN
dti-2192	78	9	functions	function	NOUN
dti-2192	78	10	of	of	ADP
dti-2192	78	11	adipocytes	adipocyte	NOUN
dti-2192	78	12	,	,	PUNCT
dti-2192	78	13	hypertrophy	hypertrophy	NOUN
dti-2192	78	14	,	,	PUNCT
dti-2192	78	15	and	and	CCONJ
dti-2192	78	16	hyperplasticity	hyperplasticity	NOUN
dti-2192	78	17	in	in	ADP
dti-2192	78	18	obesity	obesity	NOUN
dti-2192	78	19	(	(	PUNCT
dti-2192	78	20	46,47	46,47	NUM
dti-2192	78	21	)	)	PUNCT
dti-2192	78	22	.	.	PUNCT
dti-2192	79	1	obesity	obesity	NOUN
dti-2192	79	2	and	and	CCONJ
dti-2192	79	3	its	its	PRON
dti-2192	79	4	related	relate	VERB
dti-2192	79	5	comorbidities	comorbiditie	NOUN
dti-2192	79	6	facilitate	facilitate	VERB
dti-2192	79	7	viral	viral	ADJ
dti-2192	79	8	replication	replication	NOUN
dti-2192	79	9	,	,	PUNCT
dti-2192	79	10	increasing	increase	VERB
dti-2192	79	11	the	the	DET
dti-2192	79	12	risk	risk	NOUN
dti-2192	79	13	of	of	ADP
dti-2192	79	14	severe	severe	ADJ
dti-2192	79	15	complications	complication	NOUN
dti-2192	79	16	in	in	ADP
dti-2192	79	17	sars	sar	NOUN
dti-2192	79	18	-	-	PUNCT
dti-2192	79	19	cov-2	cov-2	PART
dti-2192	79	20	infections	infection	NOUN
dti-2192	79	21	.	.	PUNCT
dti-2192	80	1	this	this	DET
dti-2192	80	2	increased	increase	VERB
dti-2192	80	3	risk	risk	NOUN
dti-2192	80	4	occurs	occur	VERB
dti-2192	80	5	in	in	ADP
dti-2192	80	6	obesity	obesity	NOUN
dti-2192	80	7	because	because	SCONJ
dti-2192	80	8	the	the	DET
dti-2192	80	9	enlarged	enlarge	VERB
dti-2192	80	10	adipose	adipose	PRON
dti-2192	80	11	tissue	tissue	NOUN
dti-2192	80	12	expresses	express	VERB
dti-2192	80	13	higher	high	ADJ
dti-2192	80	14	levels	level	NOUN
dti-2192	80	15	of	of	ADP
dti-2192	80	16	ace-2	ace-2	ADJ
dti-2192	80	17	and	and	CCONJ
dti-2192	80	18	,	,	PUNCT
dti-2192	80	19	consequently	consequently	ADV
dti-2192	80	20	,	,	PUNCT
dti-2192	80	21	serves	serve	VERB
dti-2192	80	22	as	as	ADP
dti-2192	80	23	a	a	DET
dti-2192	80	24	reservoir	reservoir	NOUN
dti-2192	80	25	for	for	ADP
dti-2192	80	26	the	the	DET
dti-2192	80	27	virus	virus	NOUN
dti-2192	80	28	(	(	PUNCT
dti-2192	80	29	48	48	NUM
dti-2192	80	30	)	)	PUNCT
dti-2192	80	31	.	.	PUNCT
dti-2192	81	1	the	the	DET
dti-2192	81	2	expression	expression	NOUN
dti-2192	81	3	of	of	ADP
dti-2192	81	4	ace-2	ace-2	PUNCT
dti-2192	81	5	in	in	ADP
dti-2192	81	6	target	target	NOUN
dti-2192	81	7	tissues	tissue	NOUN
dti-2192	81	8	(	(	PUNCT
dti-2192	81	9	lung	lung	NOUN
dti-2192	81	10	,	,	PUNCT
dti-2192	81	11	liver	liver	NOUN
dti-2192	81	12	,	,	PUNCT
dti-2192	81	13	and	and	CCONJ
dti-2192	81	14	heart	heart	NOUN
dti-2192	81	15	)	)	PUNCT
dti-2192	81	16	is	be	AUX
dti-2192	81	17	increased	increase	VERB
dti-2192	81	18	in	in	ADP
dti-2192	81	19	diabetes	diabetes	NOUN
dti-2192	81	20	(	(	PUNCT
dti-2192	81	21	49	49	NUM
dti-2192	81	22	)	)	PUNCT
dti-2192	81	23	,	,	PUNCT
dti-2192	81	24	commonly	commonly	ADV
dti-2192	81	25	seen	see	VERB
dti-2192	81	26	in	in	ADP
dti-2192	81	27	obese	obese	ADJ
dti-2192	81	28	individuals	individual	NOUN
dti-2192	81	29	.	.	PUNCT
dti-2192	82	1	hyperglycemia	hyperglycemia	NOUN
dti-2192	82	2	and	and	CCONJ
dti-2192	82	3	type	type	NOUN
dti-2192	82	4	2	2	NUM
dti-2192	82	5	diabetes	diabetes	NOUN
dti-2192	82	6	also	also	ADV
dti-2192	82	7	trigger	trigger	VERB
dti-2192	82	8	the	the	DET
dti-2192	82	9	release	release	NOUN
dti-2192	82	10	of	of	ADP
dti-2192	82	11	inflammatory	inflammatory	ADJ
dti-2192	82	12	cytokines	cytokine	NOUN
dti-2192	82	13	,	,	PUNCT
dti-2192	82	14	which	which	PRON
dti-2192	82	15	in	in	ADP
dti-2192	82	16	cases	case	NOUN
dti-2192	82	17	of	of	ADP
dti-2192	82	18	covid-19	covid-19	PROPN
dti-2192	82	19	can	can	AUX
dti-2192	82	20	lead	lead	VERB
dti-2192	82	21	to	to	ADP
dti-2192	82	22	higher	high	ADJ
dti-2192	82	23	release	release	NOUN
dti-2192	82	24	of	of	ADP
dti-2192	82	25	cytokines	cytokine	NOUN
dti-2192	82	26	(	(	PUNCT
dti-2192	82	27	cytokine	cytokine	NOUN
dti-2192	82	28	storm	storm	NOUN
dti-2192	82	29	)	)	PUNCT
dti-2192	82	30	,	,	PUNCT
dti-2192	82	31	generating	generate	VERB
dti-2192	82	32	an	an	DET
dti-2192	82	33	immune	immune	ADJ
dti-2192	82	34	dysregulation	dysregulation	NOUN
dti-2192	82	35	that	that	PRON
dti-2192	82	36	can	can	AUX
dti-2192	82	37	lead	lead	VERB
dti-2192	82	38	to	to	ADP
dti-2192	82	39	multiple	multiple	ADJ
dti-2192	82	40	organ	organ	NOUN
dti-2192	82	41	failure	failure	NOUN
dti-2192	82	42	and	and	CCONJ
dti-2192	82	43	death	death	NOUN
dti-2192	82	44	(	(	PUNCT
dti-2192	82	45	50	50	NUM
dti-2192	82	46	)	)	PUNCT
dti-2192	82	47	.	.	PUNCT
dti-2192	83	1	obesity	obesity	NOUN
dti-2192	83	2	also	also	ADV
dti-2192	83	3	induces	induce	VERB
dti-2192	83	4	deregulated	deregulated	ADJ
dti-2192	83	5	lipogenesis	lipogenesis	NOUN
dti-2192	83	6	that	that	PRON
dti-2192	83	7	promotes	promote	VERB
dti-2192	83	8	the	the	DET
dti-2192	83	9	high	high	ADJ
dti-2192	83	10	expression	expression	NOUN
dti-2192	83	11	of	of	ADP
dti-2192	83	12	ace-2	ace-2	PUNCT
dti-2192	83	13	in	in	ADP
dti-2192	83	14	the	the	DET
dti-2192	83	15	lungs	lung	NOUN
dti-2192	83	16	(	(	PUNCT
dti-2192	83	17	51	51	NUM
dti-2192	83	18	)	)	PUNCT
dti-2192	83	19	.	.	PUNCT
dti-2192	84	1	the	the	DET
dti-2192	84	2	increased	increase	VERB
dti-2192	84	3	leptin	leptin	NOUN
dti-2192	84	4	synthesis	synthesis	NOUN
dti-2192	84	5	stimulated	stimulate	VERB
dti-2192	84	6	by	by	ADP
dti-2192	84	7	inflammatory	inflammatory	ADJ
dti-2192	84	8	cytokines	cytokine	NOUN
dti-2192	84	9	(	(	PUNCT
dti-2192	84	10	33	33	NUM
dti-2192	84	11	)	)	PUNCT
dti-2192	84	12	can	can	AUX
dti-2192	84	13	also	also	ADV
dti-2192	84	14	worsen	worsen	VERB
dti-2192	84	15	the	the	DET
dti-2192	84	16	clinical	clinical	ADJ
dti-2192	84	17	condition	condition	NOUN
dti-2192	84	18	of	of	ADP
dti-2192	84	19	obese	obese	ADJ
dti-2192	84	20	patients	patient	NOUN
dti-2192	84	21	with	with	ADP
dti-2192	84	22	covid-19	covid-19	PROPN
dti-2192	84	23	.	.	PUNCT
dti-2192	85	1	therefore	therefore	ADV
dti-2192	85	2	,	,	PUNCT
dti-2192	85	3	drugs	drug	NOUN
dti-2192	85	4	that	that	PRON
dti-2192	85	5	mediate	mediate	VERB
dti-2192	85	6	metabolic	metabolic	NOUN
dti-2192	85	7	responses	response	NOUN
dti-2192	85	8	targeting	target	VERB
dti-2192	85	9	ace-2	ace-2	VERB
dti-2192	85	10	have	have	AUX
dti-2192	85	11	been	be	AUX
dti-2192	85	12	considered	consider	VERB
dti-2192	85	13	promising	promise	VERB
dti-2192	85	14	in	in	ADP
dti-2192	85	15	the	the	DET
dti-2192	85	16	modulation	modulation	NOUN
dti-2192	85	17	of	of	ADP
dti-2192	85	18	glucose	glucose	NOUN
dti-2192	85	19	metabolism	metabolism	NOUN
dti-2192	85	20	and	and	CCONJ
dti-2192	85	21	blood	blood	NOUN
dti-2192	85	22	pressure	pressure	NOUN
dti-2192	85	23	control	control	NOUN
dti-2192	85	24	.	.	PUNCT
dti-2192	86	1	these	these	DET
dti-2192	86	2	drugs	drug	NOUN
dti-2192	86	3	may	may	AUX
dti-2192	86	4	also	also	ADV
dti-2192	86	5	prevent	prevent	VERB
dti-2192	86	6	the	the	DET
dti-2192	86	7	entry	entry	NOUN
dti-2192	86	8	of	of	ADP
dti-2192	86	9	the	the	DET
dti-2192	86	10	new	new	ADJ
dti-2192	86	11	coronavirus	coronavirus	NOUN
dti-2192	86	12	through	through	ADP
dti-2192	86	13	competitive	competitive	ADJ
dti-2192	86	14	pathways	pathway	NOUN
dti-2192	86	15	of	of	ADP
dti-2192	86	16	ace	ace	NOUN
dti-2192	86	17	(	(	PUNCT
dti-2192	86	18	9	9	NUM
dti-2192	86	19	)	)	PUNCT
dti-2192	86	20	.	.	PUNCT
dti-2192	87	1	results	result	NOUN
dti-2192	87	2	can	can	AUX
dti-2192	87	3	the	the	DET
dti-2192	87	4	kunitz	kunitz	PROPN
dti-2192	87	5	trypsin	trypsin	PROPN
dti-2192	87	6	inhibitor	inhibitor	NOUN
dti-2192	87	7	from	from	ADP
dti-2192	87	8	tamarind	tamarind	NOUN
dti-2192	87	9	seeds	seed	NOUN
dti-2192	87	10	combat	combat	NOUN
dti-2192	87	11	sas	sas	PROPN
dti-2192	87	12	-	-	PUNCT
dti-2192	87	13	cov-2	cov-2	PART
dti-2192	87	14	infection	infection	NOUN
dti-2192	87	15	in	in	ADP
dti-2192	87	16	obesity	obesity	NOUN
dti-2192	87	17	?	?	PUNCT
dti-2192	88	1	considering	consider	VERB
dti-2192	88	2	these	these	DET
dti-2192	88	3	dysfunctions	dysfunction	NOUN
dti-2192	88	4	in	in	ADP
dti-2192	88	5	patients	patient	NOUN
dti-2192	88	6	with	with	ADP
dti-2192	88	7	covid-19	covid-19	PROPN
dti-2192	88	8	,	,	PUNCT
dti-2192	88	9	several	several	ADJ
dti-2192	88	10	studies	study	NOUN
dti-2192	88	11	and	and	CCONJ
dti-2192	88	12	tests	test	NOUN
dti-2192	88	13	with	with	ADP
dti-2192	88	14	drugs	drug	NOUN
dti-2192	88	15	,	,	PUNCT
dti-2192	88	16	traditionally	traditionally	ADV
dti-2192	88	17	used	use	VERB
dti-2192	88	18	to	to	PART
dti-2192	88	19	control	control	VERB
dti-2192	88	20	these	these	DET
dti-2192	88	21	changes	change	NOUN
dti-2192	88	22	,	,	PUNCT
dti-2192	88	23	whether	whether	SCONJ
dti-2192	88	24	endocrine	endocrine	NOUN
dti-2192	88	25	or	or	CCONJ
dti-2192	88	26	metabolic	metabolic	NOUN
dti-2192	88	27	,	,	PUNCT
dti-2192	88	28	appear	appear	VERB
dti-2192	88	29	.	.	PUNCT
dti-2192	89	1	some	some	DET
dti-2192	89	2	adjuvant	adjuvant	ADJ
dti-2192	89	3	therapies	therapy	NOUN
dti-2192	89	4	for	for	ADP
dti-2192	89	5	covid-19	covid-19	PROPN
dti-2192	89	6	deserve	deserve	VERB
dti-2192	89	7	special	special	ADJ
dti-2192	89	8	mention	mention	NOUN
dti-2192	89	9	,	,	PUNCT
dti-2192	89	10	such	such	ADJ
dti-2192	89	11	as	as	ADP
dti-2192	89	12	immunomodulatory	immunomodulatory	ADJ
dti-2192	89	13	agents	agent	NOUN
dti-2192	89	14	,	,	PUNCT
dti-2192	89	15	immunoglobulin	immunoglobulin	NOUN
dti-2192	89	16	therapy	therapy	NOUN
dti-2192	89	17	,	,	PUNCT
dti-2192	89	18	corticosteroids	corticosteroid	NOUN
dti-2192	89	19	,	,	PUNCT
dti-2192	89	20	and	and	CCONJ
dti-2192	89	21	anticytokines	anticytokine	NOUN
dti-2192	89	22	used	use	VERB
dti-2192	89	23	to	to	PART
dti-2192	89	24	control	control	VERB
dti-2192	89	25	endocrine	endocrine	NOUN
dti-2192	89	26	and	and	CCONJ
dti-2192	89	27	metabolic	metabolic	NOUN
dti-2192	89	28	changes	change	NOUN
dti-2192	89	29	(	(	PUNCT
dti-2192	89	30	9,52,53	9,52,53	NUM
dti-2192	89	31	)	)	PUNCT
dti-2192	89	32	.	.	PUNCT
dti-2192	90	1	a	a	DET
dti-2192	90	2	new	new	ADJ
dti-2192	90	3	mechanism	mechanism	NOUN
dti-2192	90	4	related	relate	VERB
dti-2192	90	5	to	to	ADP
dti-2192	90	6	the	the	DET
dti-2192	90	7	inhibition	inhibition	NOUN
dti-2192	90	8	of	of	ADP
dti-2192	90	9	the	the	DET
dti-2192	90	10	transmembrane	transmembrane	ADJ
dti-2192	90	11	protease	protease	NOUN
dti-2192	90	12	serine	serine	NOUN
dti-2192	90	13	2	2	NUM
dti-2192	90	14	,	,	PUNCT
dti-2192	90	15	encoded	encode	VERB
dti-2192	90	16	by	by	ADP
dti-2192	90	17	the	the	DET
dti-2192	90	18	tmprss2	tmprss2	ADJ
dti-2192	90	19	gene	gene	NOUN
dti-2192	90	20	,	,	PUNCT
dti-2192	90	21	is	be	AUX
dti-2192	90	22	an	an	DET
dti-2192	90	23	additional	additional	ADJ
dti-2192	90	24	target	target	NOUN
dti-2192	90	25	for	for	ADP
dti-2192	90	26	drugs	drug	NOUN
dti-2192	90	27	for	for	ADP
dti-2192	90	28	research	research	NOUN
dti-2192	90	29	.	.	PUNCT
dti-2192	91	1	as	as	SCONJ
dti-2192	91	2	already	already	ADV
dti-2192	91	3	discussed	discuss	VERB
dti-2192	91	4	,	,	PUNCT
dti-2192	91	5	researchers	researcher	NOUN
dti-2192	91	6	have	have	AUX
dti-2192	91	7	demonstrated	demonstrate	VERB
dti-2192	91	8	that	that	SCONJ
dti-2192	91	9	sarscov-2	sarscov-2	PRON
dti-2192	91	10	uses	use	VERB
dti-2192	91	11	the	the	DET
dti-2192	91	12	sars	sar	NOUN
dti-2192	91	13	-	-	PUNCT
dti-2192	91	14	cov	cov	PROPN
dti-2192	91	15	ace-2	ace-2	PUNCT
dti-2192	91	16	receptor	receptor	NOUN
dti-2192	91	17	to	to	PART
dti-2192	91	18	enter	enter	VERB
dti-2192	91	19	cells	cell	NOUN
dti-2192	91	20	.	.	PUNCT
dti-2192	92	1	the	the	DET
dti-2192	92	2	serine	serine	NOUN
dti-2192	92	3	protease	protease	NOUN
dti-2192	92	4	tmprss2	tmprss2	PRON
dti-2192	92	5	is	be	AUX
dti-2192	92	6	also	also	ADV
dti-2192	92	7	necessary	necessary	ADJ
dti-2192	92	8	for	for	ADP
dti-2192	92	9	the	the	DET
dti-2192	92	10	initiation	initiation	NOUN
dti-2192	92	11	of	of	ADP
dti-2192	92	12	protein	protein	NOUN
dti-2192	92	13	s.	s.	PROPN
dti-2192	92	14	a	a	DET
dti-2192	92	15	tmprss2	tmprss2	ADJ
dti-2192	92	16	inhibitor	inhibitor	NOUN
dti-2192	92	17	,	,	PUNCT
dti-2192	92	18	camostat	camostat	NOUN
dti-2192	92	19	mesylate	mesylate	NOUN
dti-2192	92	20	—	—	PUNCT
dti-2192	92	21	a	a	DET
dti-2192	92	22	synthetic	synthetic	ADJ
dti-2192	92	23	serine	serine	NOUN
dti-2192	92	24	protease	protease	NOUN
dti-2192	92	25	inhibitor	inhibitor	NOUN
dti-2192	92	26	(	(	PUNCT
dti-2192	92	27	trypsin	trypsin	NOUN
dti-2192	92	28	)	)	PUNCT
dti-2192	92	29	,	,	PUNCT
dti-2192	92	30	approved	approve	VERB
dti-2192	92	31	in	in	ADP
dti-2192	92	32	japan	japan	PROPN
dti-2192	92	33	for	for	ADP
dti-2192	92	34	clinical	clinical	ADJ
dti-2192	92	35	use	use	NOUN
dti-2192	92	36	,	,	PUNCT
dti-2192	92	37	blocked	block	VERB
dti-2192	92	38	entry	entry	NOUN
dti-2192	92	39	and	and	CCONJ
dti-2192	92	40	could	could	AUX
dti-2192	92	41	be	be	AUX
dti-2192	92	42	another	another	DET
dti-2192	92	43	option	option	NOUN
dti-2192	92	44	treatment	treatment	NOUN
dti-2192	92	45	in	in	ADP
dti-2192	92	46	covid-19	covid-19	PROPN
dti-2192	92	47	(	(	PUNCT
dti-2192	92	48	9,40	9,40	NUM
dti-2192	92	49	)	)	PUNCT
dti-2192	92	50	.	.	PUNCT
dti-2192	93	1	other	other	ADJ
dti-2192	93	2	studies	study	NOUN
dti-2192	93	3	also	also	ADV
dti-2192	93	4	highlight	highlight	VERB
dti-2192	93	5	camostat	camostat	NOUN
dti-2192	93	6	mesylate	mesylate	NOUN
dti-2192	93	7	for	for	ADP
dti-2192	93	8	the	the	DET
dti-2192	93	9	treatment	treatment	NOUN
dti-2192	93	10	of	of	ADP
dti-2192	93	11	pancreatitis	pancreatitis	PROPN
dti-2192	93	12	(	(	PUNCT
dti-2192	93	13	9,52	9,52	NUM
dti-2192	93	14	)	)	PUNCT
dti-2192	93	15	currently	currently	ADV
dti-2192	93	16	in	in	ADP
dti-2192	93	17	phase	phase	NOUN
dti-2192	93	18	2	2	NUM
dti-2192	93	19	clinical	clinical	ADJ
dti-2192	93	20	trial	trial	NOUN
dti-2192	93	21	in	in	ADP
dti-2192	93	22	covid-19	covid-19	PROPN
dti-2192	93	23	.	.	PUNCT
dti-2192	94	1	furthermore	furthermore	ADV
dti-2192	94	2	,	,	PUNCT
dti-2192	94	3	inhibition	inhibition	NOUN
dti-2192	94	4	of	of	ADP
dti-2192	94	5	3cl	3cl	ADJ
dti-2192	94	6	pro	pro	NOUN
dti-2192	94	7	can	can	AUX
dti-2192	94	8	block	block	VERB
dti-2192	94	9	protein	protein	NOUN
dti-2192	94	10	s	s	PART
dti-2192	94	11	synthesis	synthesis	NOUN
dti-2192	94	12	and	and	CCONJ
dti-2192	94	13	coronavirus	coronavirus	NOUN
dti-2192	94	14	proliferation	proliferation	NOUN
dti-2192	94	15	(	(	PUNCT
dti-2192	94	16	39	39	NUM
dti-2192	94	17	)	)	PUNCT
dti-2192	94	18	.	.	PUNCT
dti-2192	95	1	most	most	ADJ
dti-2192	95	2	studies	study	NOUN
dti-2192	95	3	have	have	AUX
dti-2192	95	4	focused	focus	VERB
dti-2192	95	5	mainly	mainly	ADV
dti-2192	95	6	on	on	ADP
dti-2192	95	7	small	small	ADJ
dti-2192	95	8	-	-	PUNCT
dti-2192	95	9	molecule	molecule	NOUN
dti-2192	95	10	compounds	compound	NOUN
dti-2192	95	11	from	from	ADP
dti-2192	95	12	virtual	virtual	ADJ
dti-2192	95	13	screening	screening	NOUN
dti-2192	95	14	based	base	VERB
dti-2192	95	15	on	on	ADP
dti-2192	95	16	a	a	DET
dti-2192	95	17	3cl	3cl	ADJ
dti-2192	95	18	pro	pro	ADJ
dti-2192	95	19	structure	structure	NOUN
dti-2192	95	20	(	(	PUNCT
dti-2192	95	21	54	54	NUM
dti-2192	95	22	)	)	PUNCT
dti-2192	95	23	.	.	PUNCT
dti-2192	96	1	several	several	ADJ
dti-2192	96	2	inhibitors	inhibitor	NOUN
dti-2192	96	3	,	,	PUNCT
dti-2192	96	4	which	which	PRON
dti-2192	96	5	can	can	AUX
dti-2192	96	6	be	be	AUX
dti-2192	96	7	classified	classify	VERB
dti-2192	96	8	as	as	ADP
dti-2192	96	9	peptoids	peptoid	NOUN
dti-2192	96	10	and	and	CCONJ
dti-2192	96	11	non	non	NOUN
dti-2192	96	12	-	-	NOUN
dti-2192	96	13	peptidomimetics	peptidomimetic	NOUN
dti-2192	96	14	,	,	PUNCT
dti-2192	96	15	have	have	AUX
dti-2192	96	16	shown	show	VERB
dti-2192	96	17	good	good	ADJ
dti-2192	96	18	inhibitory	inhibitory	ADJ
dti-2192	96	19	activity	activity	NOUN
dti-2192	96	20	of	of	ADP
dti-2192	96	21	this	this	DET
dti-2192	96	22	protease	protease	NOUN
dti-2192	96	23	(	(	PUNCT
dti-2192	96	24	39	39	NUM
dti-2192	96	25	)	)	PUNCT
dti-2192	96	26	.	.	PUNCT
dti-2192	97	1	protease	protease	NOUN
dti-2192	97	2	inhibitors	inhibitor	NOUN
dti-2192	97	3	have	have	AUX
dti-2192	97	4	been	be	AUX
dti-2192	97	5	widely	widely	ADV
dti-2192	97	6	studied	study	VERB
dti-2192	97	7	.	.	PUNCT
dti-2192	98	1	one	one	NUM
dti-2192	98	2	reason	reason	NOUN
dti-2192	98	3	is	be	AUX
dti-2192	98	4	that	that	SCONJ
dti-2192	98	5	they	they	PRON
dti-2192	98	6	are	be	AUX
dti-2192	98	7	present	present	ADJ
dti-2192	98	8	in	in	ADP
dti-2192	98	9	multiple	multiple	ADJ
dti-2192	98	10	forms	form	NOUN
dti-2192	98	11	in	in	ADP
dti-2192	98	12	plants	plant	NOUN
dti-2192	98	13	,	,	PUNCT
dti-2192	98	14	animals	animal	NOUN
dti-2192	98	15	,	,	PUNCT
dti-2192	98	16	and	and	CCONJ
dti-2192	98	17	microorganisms	microorganism	NOUN
dti-2192	98	18	.	.	PUNCT
dti-2192	99	1	in	in	ADP
dti-2192	99	2	addition	addition	NOUN
dti-2192	99	3	,	,	PUNCT
dti-2192	99	4	protease	protease	NOUN
dti-2192	99	5	inhibitors	inhibitor	NOUN
dti-2192	99	6	are	be	AUX
dti-2192	99	7	natural	natural	ADJ
dti-2192	99	8	protease	protease	NOUN
dti-2192	99	9	regulators	regulator	NOUN
dti-2192	99	10	that	that	PRON
dti-2192	99	11	are	be	AUX
dti-2192	99	12	intrinsically	intrinsically	ADV
dti-2192	99	13	involved	involve	VERB
dti-2192	99	14	in	in	ADP
dti-2192	99	15	biological	biological	ADJ
dti-2192	99	16	processes	process	NOUN
dti-2192	99	17	such	such	ADJ
dti-2192	99	18	as	as	ADP
dti-2192	99	19	digestion	digestion	NOUN
dti-2192	99	20	,	,	PUNCT
dti-2192	99	21	healing	healing	NOUN
dti-2192	99	22	,	,	PUNCT
dti-2192	99	23	viral	viral	ADJ
dti-2192	99	24	replication	replication	NOUN
dti-2192	99	25	,	,	PUNCT
dti-2192	99	26	and	and	CCONJ
dti-2192	99	27	the	the	DET
dti-2192	99	28	blood	blood	NOUN
dti-2192	99	29	clotting	clot	VERB
dti-2192	99	30	cascade	cascade	NOUN
dti-2192	99	31	,	,	PUNCT
dti-2192	99	32	among	among	ADP
dti-2192	99	33	others	other	NOUN
dti-2192	99	34	,	,	PUNCT
dti-2192	99	35	and	and	CCONJ
dti-2192	99	36	that	that	PRON
dti-2192	99	37	need	need	VERB
dti-2192	99	38	precise	precise	ADJ
dti-2192	99	39	regulation	regulation	NOUN
dti-2192	99	40	(	(	PUNCT
dti-2192	99	41	55,56	55,56	NOUN
dti-2192	99	42	)	)	PUNCT
dti-2192	99	43	.	.	PUNCT
dti-2192	100	1	thus	thus	ADV
dti-2192	100	2	,	,	PUNCT
dti-2192	100	3	the	the	DET
dti-2192	100	4	prospect	prospect	NOUN
dti-2192	100	5	of	of	ADP
dti-2192	100	6	peptides	peptide	NOUN
dti-2192	100	7	for	for	ADP
dti-2192	100	8	use	use	NOUN
dti-2192	100	9	in	in	ADP
dti-2192	100	10	biotechnology	biotechnology	NOUN
dti-2192	100	11	has	have	AUX
dti-2192	100	12	led	lead	VERB
dti-2192	100	13	to	to	ADP
dti-2192	100	14	a	a	DET
dti-2192	100	15	number	number	NOUN
dti-2192	100	16	of	of	ADP
dti-2192	100	17	molecules	molecule	NOUN
dti-2192	100	18	’	'	PUNCT
dti-2192	100	19	discovery	discovery	NOUN
dti-2192	100	20	.	.	PUNCT
dti-2192	101	1	its	its	PRON
dti-2192	101	2	use	use	NOUN
dti-2192	101	3	in	in	ADP
dti-2192	101	4	experimental	experimental	ADJ
dti-2192	101	5	models	model	NOUN
dti-2192	101	6	has	have	AUX
dti-2192	101	7	exposed	expose	VERB
dti-2192	101	8	mammals	mammal	NOUN
dti-2192	101	9	to	to	ADP
dti-2192	101	10	risks	risk	NOUN
dti-2192	101	11	that	that	PRON
dti-2192	101	12	have	have	AUX
dti-2192	101	13	not	not	PART
dti-2192	101	14	yet	yet	ADV
dti-2192	101	15	been	be	AUX
dti-2192	101	16	evaluated	evaluate	VERB
dti-2192	101	17	.	.	PUNCT
dti-2192	102	1	although	although	SCONJ
dti-2192	102	2	the	the	DET
dti-2192	102	3	benefits	benefit	NOUN
dti-2192	102	4	of	of	ADP
dti-2192	102	5	proteins	protein	NOUN
dti-2192	102	6	and	and	CCONJ
dti-2192	102	7	peptides	peptide	NOUN
dti-2192	102	8	substantially	substantially	ADV
dti-2192	102	9	outweigh	outweigh	VERB
dti-2192	102	10	the	the	DET
dti-2192	102	11	potential	potential	ADJ
dti-2192	102	12	harmful	harmful	ADJ
dti-2192	102	13	effects	effect	NOUN
dti-2192	102	14	,	,	PUNCT
dti-2192	102	15	their	their	PRON
dti-2192	102	16	use	use	NOUN
dti-2192	102	17	is	be	AUX
dti-2192	102	18	not	not	PART
dti-2192	102	19	without	without	ADP
dti-2192	102	20	risks	risk	NOUN
dti-2192	102	21	.	.	PUNCT
dti-2192	103	1	there	there	PRON
dti-2192	103	2	is	be	VERB
dti-2192	103	3	a	a	DET
dti-2192	103	4	balance	balance	NOUN
dti-2192	103	5	between	between	ADP
dti-2192	103	6	the	the	DET
dti-2192	103	7	ability	ability	NOUN
dti-2192	103	8	of	of	ADP
dti-2192	103	9	peptides	peptide	NOUN
dti-2192	103	10	to	to	PART
dti-2192	103	11	induce	induce	VERB
dti-2192	103	12	desirable	desirable	ADJ
dti-2192	103	13	effects	effect	NOUN
dti-2192	103	14	,	,	PUNCT
dti-2192	103	15	that	that	ADV
dti-2192	103	16	is	is	ADV
dti-2192	103	17	,	,	PUNCT
dti-2192	103	18	their	their	PRON
dti-2192	103	19	bioactivity	bioactivity	NOUN
dti-2192	103	20	,	,	PUNCT
dti-2192	103	21	and	and	CCONJ
dti-2192	103	22	the	the	DET
dti-2192	103	23	potential	potential	ADJ
dti-2192	103	24	toxic	toxic	ADJ
dti-2192	103	25	effects	effect	NOUN
dti-2192	103	26	associated	associate	VERB
dti-2192	103	27	with	with	ADP
dti-2192	103	28	their	their	PRON
dti-2192	103	29	cell	cell	NOUN
dti-2192	103	30	-	-	PUNCT
dti-2192	103	31	penetrating	penetrate	VERB
dti-2192	103	32	properties	property	NOUN
dti-2192	103	33	(	(	PUNCT
dti-2192	103	34	57	57	NUM
dti-2192	103	35	)	)	PUNCT
dti-2192	103	36	.	.	PUNCT
dti-2192	104	1	among	among	ADP
dti-2192	104	2	protease	protease	NOUN
dti-2192	104	3	inhibitors	inhibitor	NOUN
dti-2192	104	4	,	,	PUNCT
dti-2192	104	5	trypsin	trypsin	NOUN
dti-2192	104	6	inhibitors	inhibitor	NOUN
dti-2192	104	7	are	be	AUX
dti-2192	104	8	widely	widely	ADV
dti-2192	104	9	extracted	extract	VERB
dti-2192	104	10	from	from	ADP
dti-2192	104	11	seeds	seed	NOUN
dti-2192	104	12	to	to	PART
dti-2192	104	13	be	be	AUX
dti-2192	104	14	purified	purify	VERB
dti-2192	104	15	and	and	CCONJ
dti-2192	104	16	characterized	characterize	VERB
dti-2192	104	17	for	for	ADP
dti-2192	104	18	application	application	NOUN
dti-2192	104	19	in	in	ADP
dti-2192	104	20	various	various	ADJ
dti-2192	104	21	studies	study	NOUN
dti-2192	104	22	(	(	PUNCT
dti-2192	104	23	58	58	NUM
dti-2192	104	24	)	)	PUNCT
dti-2192	104	25	.	.	PUNCT
dti-2192	105	1	these	these	DET
dti-2192	105	2	molecules	molecule	NOUN
dti-2192	105	3	have	have	AUX
dti-2192	105	4	shown	show	VERB
dti-2192	105	5	,	,	PUNCT
dti-2192	105	6	in	in	ADP
dti-2192	105	7	recent	recent	ADJ
dti-2192	105	8	studies	study	NOUN
dti-2192	105	9	,	,	PUNCT
dti-2192	105	10	performance	performance	NOUN
dti-2192	105	11	in	in	ADP
dti-2192	105	12	different	different	ADJ
dti-2192	105	13	mechanisms	mechanism	NOUN
dti-2192	105	14	involving	involve	VERB
dti-2192	105	15	the	the	DET
dti-2192	105	16	control	control	NOUN
dti-2192	105	17	of	of	ADP
dti-2192	105	18	obesity	obesity	NOUN
dti-2192	105	19	and	and	CCONJ
dti-2192	105	20	its	its	PRON
dti-2192	105	21	related	related	ADJ
dti-2192	105	22	effects	effect	NOUN
dti-2192	105	23	,	,	PUNCT
dti-2192	105	24	such	such	ADJ
dti-2192	105	25	as	as	ADP
dti-2192	105	26	the	the	DET
dti-2192	105	27	production	production	NOUN
dti-2192	105	28	of	of	ADP
dti-2192	105	29	hormones	hormone	NOUN
dti-2192	105	30	related	relate	VERB
dti-2192	105	31	to	to	ADP
dti-2192	105	32	satiety	satiety	NOUN
dti-2192	105	33	,	,	PUNCT
dti-2192	105	34	affecting	affect	VERB
dti-2192	105	35	the	the	DET
dti-2192	105	36	central	central	ADJ
dti-2192	105	37	nervous	nervous	ADJ
dti-2192	105	38	system	system	NOUN
dti-2192	105	39	and	and	CCONJ
dti-2192	105	40	the	the	DET
dti-2192	105	41	small	small	ADJ
dti-2192	105	42	intestine	intestine	NOUN
dti-2192	105	43	;	;	PUNCT
dti-2192	105	44	reduction	reduction	NOUN
dti-2192	105	45	of	of	ADP
dti-2192	105	46	food	food	NOUN
dti-2192	105	47	consumption	consumption	NOUN
dti-2192	105	48	and	and	CCONJ
dti-2192	105	49	weight	weight	NOUN
dti-2192	105	50	gain	gain	NOUN
dti-2192	105	51	;	;	PUNCT
dti-2192	105	52	improvement	improvement	NOUN
dti-2192	105	53	of	of	ADP
dti-2192	105	54	the	the	DET
dti-2192	105	55	lipid	lipid	NOUN
dti-2192	105	56	profile	profile	NOUN
dti-2192	105	57	;	;	PUNCT
dti-2192	105	58	and	and	CCONJ
dti-2192	105	59	reduction	reduction	NOUN
dti-2192	105	60	of	of	ADP
dti-2192	105	61	the	the	DET
dti-2192	105	62	inflammatory	inflammatory	ADJ
dti-2192	105	63	process	process	NOUN
dti-2192	105	64	associated	associate	VERB
dti-2192	105	65	with	with	ADP
dti-2192	105	66	obesity	obesity	NOUN
dti-2192	105	67	,	,	PUNCT
dti-2192	105	68	regardless	regardless	ADV
dti-2192	105	69	of	of	ADP
dti-2192	105	70	weight	weight	NOUN
dti-2192	105	71	loss	loss	NOUN
dti-2192	105	72	(	(	PUNCT
dti-2192	105	73	59	59	NUM
dti-2192	105	74	)	)	PUNCT
dti-2192	105	75	.	.	PUNCT
dti-2192	106	1	a	a	DET
dti-2192	106	2	trypsin	trypsin	NOUN
dti-2192	106	3	inhibitor	inhibitor	NOUN
dti-2192	106	4	extracted	extract	VERB
dti-2192	106	5	from	from	ADP
dti-2192	106	6	seeds	seed	NOUN
dti-2192	106	7	of	of	ADP
dti-2192	106	8	the	the	DET
dti-2192	106	9	tamarind	tamarind	NOUN
dti-2192	106	10	fruit	fruit	NOUN
dti-2192	106	11	,	,	PUNCT
dti-2192	106	12	tamarindus	tamarindu	VERB
dti-2192	106	13	indica	indica	PROPN
dti-2192	106	14	l.	l.	PROPN
dti-2192	106	15	,	,	PUNCT
dti-2192	106	16	belonging	belong	VERB
dti-2192	106	17	to	to	ADP
dti-2192	106	18	the	the	DET
dti-2192	106	19	legume	legume	NOUN
dti-2192	106	20	family	family	NOUN
dti-2192	106	21	,	,	PUNCT
dti-2192	106	22	occurring	occur	VERB
dti-2192	106	23	in	in	ADP
dti-2192	106	24	all	all	DET
dti-2192	106	25	regions	region	NOUN
dti-2192	106	26	of	of	ADP
dti-2192	106	27	brazil	brazil	PROPN
dti-2192	106	28	(	(	PUNCT
dti-2192	106	29	60	60	NUM
dti-2192	106	30	)	)	PUNCT
dti-2192	106	31	has	have	AUX
dti-2192	106	32	been	be	AUX
dti-2192	106	33	extensively	extensively	ADV
dti-2192	106	34	studied	study	VERB
dti-2192	106	35	by	by	ADP
dti-2192	106	36	our	our	PRON
dti-2192	106	37	research	research	NOUN
dti-2192	106	38	group	group	NOUN
dti-2192	106	39	.	.	PUNCT
dti-2192	107	1	the	the	DET
dti-2192	107	2	first	first	ADJ
dti-2192	107	3	study	study	NOUN
dti-2192	107	4	to	to	PART
dti-2192	107	5	evaluate	evaluate	VERB
dti-2192	107	6	the	the	DET
dti-2192	107	7	potential	potential	NOUN
dti-2192	107	8	of	of	ADP
dti-2192	107	9	the	the	DET
dti-2192	107	10	tamarind	tamarind	NOUN
dti-2192	107	11	trypsin	trypsin	NOUN
dti-2192	107	12	inhibitor	inhibitor	NOUN
dti-2192	107	13	(	(	PUNCT
dti-2192	107	14	tti	tti	PROPN
dti-2192	107	15	)	)	PUNCT
dti-2192	107	16	to	to	PART
dti-2192	107	17	reduce	reduce	VERB
dti-2192	107	18	weight	weight	NOUN
dti-2192	107	19	gain	gain	NOUN
dti-2192	107	20	was	be	AUX
dti-2192	107	21	developed	develop	VERB
dti-2192	107	22	by	by	ADP
dti-2192	107	23	ribeiro	ribeiro	PROPN
dti-2192	107	24	et	et	PROPN
dti-2192	107	25	al	al	PROPN
dti-2192	107	26	(	(	PUNCT
dti-2192	107	27	61	61	NUM
dti-2192	107	28	)	)	PUNCT
dti-2192	107	29	.	.	PUNCT
dti-2192	108	1	in	in	ADP
dti-2192	108	2	this	this	DET
dti-2192	108	3	study	study	NOUN
dti-2192	108	4	,	,	PUNCT
dti-2192	108	5	male	male	ADJ
dti-2192	108	6	eutrophic	eutrophic	NOUN
dti-2192	108	7	wistar	wistar	PROPN
dti-2192	108	8	rats	rat	NOUN
dti-2192	108	9	were	be	AUX
dti-2192	108	10	fed	feed	VERB
dti-2192	108	11	a	a	DET
dti-2192	108	12	standard	standard	ADJ
dti-2192	108	13	diet	diet	NOUN
dti-2192	108	14	and	and	CCONJ
dti-2192	108	15	received	receive	VERB
dti-2192	108	16	the	the	DET
dti-2192	108	17	isolated	isolated	ADJ
dti-2192	108	18	tti	tti	PROPN
dti-2192	108	19	by	by	ADP
dti-2192	108	20	gavage	gavage	NOUN
dti-2192	108	21	for	for	ADP
dti-2192	108	22	11	11	NUM
dti-2192	108	23	days	day	NOUN
dti-2192	108	24	at	at	ADP
dti-2192	108	25	a	a	DET
dti-2192	108	26	dose	dose	NOUN
dti-2192	108	27	of	of	ADP
dti-2192	108	28	25	25	NUM
dti-2192	108	29	mg	mg	PROPN
dti-2192	108	30	/	/	SYM
dti-2192	108	31	kg	kg	PROPN
dti-2192	108	32	.	.	PUNCT
dti-2192	109	1	tti	tti	PROPN
dti-2192	109	2	administration	administration	PROPN
dti-2192	109	3	reduced	reduce	VERB
dti-2192	109	4	food	food	NOUN
dti-2192	109	5	intake	intake	NOUN
dti-2192	109	6	in	in	ADP
dti-2192	109	7	these	these	DET
dti-2192	109	8	animals	animal	NOUN
dti-2192	109	9	.	.	PUNCT
dti-2192	110	1	to	to	PART
dti-2192	110	2	better	well	ADV
dti-2192	110	3	understand	understand	VERB
dti-2192	110	4	this	this	DET
dti-2192	110	5	reduction	reduction	NOUN
dti-2192	110	6	in	in	ADP
dti-2192	110	7	consumption	consumption	NOUN
dti-2192	110	8	,	,	PUNCT
dti-2192	110	9	another	another	DET
dti-2192	110	10	experiment	experiment	NOUN
dti-2192	110	11	using	use	VERB
dti-2192	110	12	the	the	DET
dti-2192	110	13	same	same	ADJ
dti-2192	110	14	experimental	experimental	ADJ
dti-2192	110	15	model	model	NOUN
dti-2192	110	16	evaluated	evaluate	VERB
dti-2192	110	17	food	food	NOUN
dti-2192	110	18	consumption	consumption	NOUN
dti-2192	110	19	1	1	NUM
dti-2192	110	20	h	h	NOUN
dti-2192	110	21	,	,	PUNCT
dti-2192	110	22	2	2	NUM
dti-2192	110	23	h	h	NOUN
dti-2192	110	24	,	,	PUNCT
dti-2192	110	25	and	and	CCONJ
dti-2192	110	26	16	16	NUM
dti-2192	110	27	h	h	NOUN
dti-2192	110	28	after	after	ADP
dti-2192	110	29	gavage	gavage	NOUN
dti-2192	110	30	with	with	ADP
dti-2192	110	31	tti	tti	PROPN
dti-2192	110	32	,	,	PUNCT
dti-2192	110	33	in	in	ADP
dti-2192	110	34	addition	addition	NOUN
dti-2192	110	35	to	to	PART
dti-2192	110	36	serum	serum	VERB
dti-2192	110	37	cholecystokinin	cholecystokinin	NOUN
dti-2192	110	38	(	(	PUNCT
dti-2192	110	39	cck	cck	NOUN
dti-2192	110	40	)	)	PUNCT
dti-2192	110	41	,	,	PUNCT
dti-2192	110	42	using	use	VERB
dti-2192	110	43	doses	dose	NOUN
dti-2192	110	44	of	of	ADP
dti-2192	110	45	25	25	NUM
dti-2192	110	46	and	and	CCONJ
dti-2192	110	47	50	50	NUM
dti-2192	110	48	mg	mg	NUM
dti-2192	110	49	/	/	SYM
dti-2192	110	50	kg	kg	PROPN
dti-2192	110	51	.	.	PUNCT
dti-2192	111	1	tti	tti	PROPN
dti-2192	111	2	protein	protein	NOUN
dti-2192	111	3	with	with	ADP
dti-2192	111	4	potential	potential	NOUN
dti-2192	111	5	for	for	ADP
dti-2192	111	6	combating	combat	VERB
dti-2192	111	7	sars	sar	NOUN
dti-2192	111	8	-	-	PUNCT
dti-2192	111	9	cov-2	cov-2	PART
dti-2192	111	10	infection	infection	NOUN
dti-2192	111	11	in	in	ADP
dti-2192	111	12	obesity8	obesity8	NOUN
dti-2192	112	1	©	©	ADP
dti-2192	112	2	2021	2021	NUM
dti-2192	113	1	the	the	DET
dti-2192	113	2	authors	author	NOUN
dti-2192	113	3	.	.	PUNCT
dti-2192	114	1	drug	drug	NOUN
dti-2192	114	2	target	target	NOUN
dti-2192	114	3	insights	insight	NOUN
dti-2192	114	4	issn	issn	VERB
dti-2192	114	5	1177	1177	NUM
dti-2192	114	6	-	-	SYM
dti-2192	114	7	3928	3928	NUM
dti-2192	114	8	www.aboutscience.eu/dti	www.aboutscience.eu/dti	NOUN
dti-2192	114	9	reduced	reduce	VERB
dti-2192	114	10	food	food	NOUN
dti-2192	114	11	consumption	consumption	NOUN
dti-2192	114	12	16	16	NUM
dti-2192	114	13	h	h	NOUN
dti-2192	114	14	after	after	ADP
dti-2192	114	15	its	its	PRON
dti-2192	114	16	administration	administration	NOUN
dti-2192	114	17	dosedependently	dosedependently	ADV
dti-2192	114	18	(	(	PUNCT
dti-2192	114	19	61	61	NUM
dti-2192	114	20	)	)	PUNCT
dti-2192	114	21	.	.	PUNCT
dti-2192	115	1	in	in	ADP
dti-2192	115	2	this	this	DET
dti-2192	115	3	study	study	NOUN
dti-2192	115	4	,	,	PUNCT
dti-2192	115	5	tti	tti	PROPN
dti-2192	115	6	did	do	AUX
dti-2192	115	7	not	not	PART
dti-2192	115	8	cause	cause	VERB
dti-2192	115	9	changes	change	NOUN
dti-2192	115	10	in	in	ADP
dti-2192	115	11	the	the	DET
dti-2192	115	12	liver	liver	NOUN
dti-2192	115	13	enzymes	enzyme	NOUN
dti-2192	115	14	and	and	CCONJ
dti-2192	115	15	serum	serum	NOUN
dti-2192	115	16	proteins	protein	NOUN
dti-2192	115	17	of	of	ADP
dti-2192	115	18	wistar	wistar	PROPN
dti-2192	115	19	rats	rat	NOUN
dti-2192	115	20	,	,	PUNCT
dti-2192	115	21	in	in	ADP
dti-2192	115	22	addition	addition	NOUN
dti-2192	115	23	to	to	ADP
dti-2192	115	24	not	not	PART
dti-2192	115	25	affecting	affect	VERB
dti-2192	115	26	the	the	DET
dti-2192	115	27	histological	histological	ADJ
dti-2192	115	28	aspects	aspect	NOUN
dti-2192	115	29	of	of	ADP
dti-2192	115	30	the	the	DET
dti-2192	115	31	liver	liver	NOUN
dti-2192	115	32	,	,	PUNCT
dti-2192	115	33	stomach	stomach	NOUN
dti-2192	115	34	,	,	PUNCT
dti-2192	115	35	intestine	intestine	NOUN
dti-2192	115	36	,	,	PUNCT
dti-2192	115	37	and	and	CCONJ
dti-2192	115	38	pancreas	pancrea	NOUN
dti-2192	115	39	.	.	PUNCT
dti-2192	116	1	in	in	ADP
dti-2192	116	2	addition	addition	NOUN
dti-2192	116	3	,	,	PUNCT
dti-2192	116	4	tti	tti	PROPN
dti-2192	116	5	did	do	AUX
dti-2192	116	6	not	not	PART
dti-2192	116	7	cause	cause	VERB
dti-2192	116	8	classical	classical	ADJ
dti-2192	116	9	deleterious	deleterious	ADJ
dti-2192	116	10	effects	effect	NOUN
dti-2192	116	11	on	on	ADP
dti-2192	116	12	protein	protein	NOUN
dti-2192	116	13	digestion	digestion	NOUN
dti-2192	116	14	and	and	CCONJ
dti-2192	116	15	,	,	PUNCT
dti-2192	116	16	consequently	consequently	ADV
dti-2192	116	17	,	,	PUNCT
dti-2192	116	18	malnutrition	malnutrition	NOUN
dti-2192	116	19	at	at	ADP
dti-2192	116	20	the	the	DET
dti-2192	116	21	doses	dose	NOUN
dti-2192	116	22	tested	test	VERB
dti-2192	116	23	,	,	PUNCT
dti-2192	116	24	as	as	SCONJ
dti-2192	116	25	demonstrated	demonstrate	VERB
dti-2192	116	26	by	by	ADP
dti-2192	116	27	the	the	DET
dti-2192	116	28	measurement	measurement	NOUN
dti-2192	116	29	of	of	ADP
dti-2192	116	30	serum	serum	NOUN
dti-2192	116	31	proteins	protein	NOUN
dti-2192	116	32	.	.	PUNCT
dti-2192	117	1	obesity	obesity	NOUN
dti-2192	117	2	is	be	AUX
dti-2192	117	3	a	a	DET
dti-2192	117	4	condition	condition	NOUN
dti-2192	117	5	that	that	PRON
dti-2192	117	6	leads	lead	VERB
dti-2192	117	7	to	to	ADP
dti-2192	117	8	numerous	numerous	ADJ
dti-2192	117	9	physiological	physiological	ADJ
dti-2192	117	10	changes	change	NOUN
dti-2192	117	11	,	,	PUNCT
dti-2192	117	12	and	and	CCONJ
dti-2192	117	13	the	the	DET
dti-2192	117	14	behavior	behavior	NOUN
dti-2192	117	15	of	of	ADP
dti-2192	117	16	tti	tti	PROPN
dti-2192	117	17	in	in	ADP
dti-2192	117	18	this	this	DET
dti-2192	117	19	condition	condition	NOUN
dti-2192	117	20	needs	need	VERB
dti-2192	117	21	to	to	PART
dti-2192	117	22	be	be	AUX
dti-2192	117	23	assessed	assess	VERB
dti-2192	117	24	.	.	PUNCT
dti-2192	118	1	for	for	ADP
dti-2192	118	2	this	this	PRON
dti-2192	118	3	,	,	PUNCT
dti-2192	118	4	carvalho	carvalho	PROPN
dti-2192	118	5	et	et	PROPN
dti-2192	118	6	al	al	PROPN
dti-2192	118	7	(	(	PUNCT
dti-2192	118	8	62	62	NUM
dti-2192	118	9	)	)	PUNCT
dti-2192	118	10	used	use	VERB
dti-2192	118	11	wistar	wistar	PROPN
dti-2192	118	12	rats	rat	NOUN
dti-2192	118	13	with	with	ADP
dti-2192	118	14	diet	diet	NOUN
dti-2192	118	15	-	-	PUNCT
dti-2192	118	16	induced	induce	VERB
dti-2192	118	17	obesity	obesity	NOUN
dti-2192	118	18	,	,	PUNCT
dti-2192	118	19	assessing	assess	VERB
dti-2192	118	20	food	food	NOUN
dti-2192	118	21	consumption	consumption	NOUN
dti-2192	118	22	and	and	CCONJ
dti-2192	118	23	other	other	ADJ
dti-2192	118	24	biochemical	biochemical	ADJ
dti-2192	118	25	parameters	parameter	NOUN
dti-2192	118	26	,	,	PUNCT
dti-2192	118	27	using	use	VERB
dti-2192	118	28	the	the	DET
dti-2192	118	29	25	25	NUM
dti-2192	118	30	mg	mg	PROPN
dti-2192	118	31	/	/	SYM
dti-2192	118	32	kg	kg	PROPN
dti-2192	118	33	dose	dose	NOUN
dti-2192	118	34	of	of	ADP
dti-2192	118	35	tti	tti	PROPN
dti-2192	118	36	,	,	PUNCT
dti-2192	118	37	as	as	SCONJ
dti-2192	118	38	proposed	propose	VERB
dti-2192	118	39	by	by	ADP
dti-2192	118	40	ribeiro	ribeiro	PROPN
dti-2192	118	41	et	et	PROPN
dti-2192	118	42	al	al	PROPN
dti-2192	118	43	(	(	PUNCT
dti-2192	118	44	61	61	NUM
dti-2192	118	45	)	)	PUNCT
dti-2192	118	46	.	.	PUNCT
dti-2192	119	1	in	in	ADP
dti-2192	119	2	animals	animal	NOUN
dti-2192	119	3	with	with	ADP
dti-2192	119	4	obesity	obesity	NOUN
dti-2192	119	5	,	,	PUNCT
dti-2192	119	6	tti	tti	PROPN
dti-2192	119	7	reduced	reduce	VERB
dti-2192	119	8	food	food	NOUN
dti-2192	119	9	consumption	consumption	NOUN
dti-2192	119	10	without	without	ADP
dti-2192	119	11	inducing	induce	VERB
dti-2192	119	12	weight	weight	NOUN
dti-2192	119	13	loss	loss	NOUN
dti-2192	119	14	.	.	PUNCT
dti-2192	120	1	tti	tti	PROPN
dti-2192	120	2	reduced	reduce	VERB
dti-2192	120	3	plasma	plasma	PROPN
dti-2192	120	4	tnf	tnf	PROPN
dti-2192	120	5	-	-	PUNCT
dti-2192	120	6	α	α	NOUN
dti-2192	120	7	to	to	ADP
dti-2192	120	8	undetectable	undetectable	ADJ
dti-2192	120	9	concentrations	concentration	NOUN
dti-2192	120	10	,	,	PUNCT
dti-2192	120	11	showing	show	VERB
dti-2192	120	12	that	that	SCONJ
dti-2192	120	13	the	the	DET
dti-2192	120	14	isolated	isolated	ADJ
dti-2192	120	15	inhibitor	inhibitor	NOUN
dti-2192	120	16	also	also	ADV
dti-2192	120	17	influenced	influence	VERB
dti-2192	120	18	other	other	ADJ
dti-2192	120	19	aspects	aspect	NOUN
dti-2192	120	20	related	relate	VERB
dti-2192	120	21	to	to	ADP
dti-2192	120	22	obesity	obesity	NOUN
dti-2192	120	23	,	,	PUNCT
dti-2192	120	24	such	such	ADJ
dti-2192	120	25	as	as	ADP
dti-2192	120	26	low	low	ADJ
dti-2192	120	27	-	-	PUNCT
dti-2192	120	28	grade	grade	NOUN
dti-2192	120	29	chronic	chronic	ADJ
dti-2192	120	30	inflammation	inflammation	NOUN
dti-2192	120	31	(	(	PUNCT
dti-2192	120	32	62	62	NUM
dti-2192	120	33	)	)	PUNCT
dti-2192	120	34	.	.	PUNCT
dti-2192	121	1	in	in	ADP
dti-2192	121	2	the	the	DET
dti-2192	121	3	same	same	ADJ
dti-2192	121	4	experimental	experimental	ADJ
dti-2192	121	5	model	model	NOUN
dti-2192	121	6	of	of	ADP
dti-2192	121	7	obesity	obesity	NOUN
dti-2192	121	8	,	,	PUNCT
dti-2192	121	9	costa	costa	PROPN
dti-2192	121	10	et	et	PROPN
dti-2192	121	11	al	al	PROPN
dti-2192	121	12	(	(	PUNCT
dti-2192	121	13	63	63	NUM
dti-2192	121	14	)	)	PUNCT
dti-2192	121	15	observed	observe	VERB
dti-2192	121	16	that	that	SCONJ
dti-2192	121	17	animals	animal	NOUN
dti-2192	121	18	with	with	ADP
dti-2192	121	19	obesity	obesity	NOUN
dti-2192	121	20	treated	treat	VERB
dti-2192	121	21	with	with	ADP
dti-2192	121	22	tti	tti	PROPN
dti-2192	121	23	decreased	decrease	VERB
dti-2192	121	24	food	food	NOUN
dti-2192	121	25	intake	intake	NOUN
dti-2192	121	26	in	in	ADP
dti-2192	121	27	a	a	DET
dti-2192	121	28	similar	similar	ADJ
dti-2192	121	29	way	way	NOUN
dti-2192	121	30	to	to	ADP
dti-2192	121	31	eutrophic	eutrophic	ADJ
dti-2192	121	32	animals	animal	NOUN
dti-2192	121	33	.	.	PUNCT
dti-2192	122	1	the	the	DET
dti-2192	122	2	animals	animal	NOUN
dti-2192	122	3	with	with	ADP
dti-2192	122	4	obesity	obesity	NOUN
dti-2192	122	5	treated	treat	VERB
dti-2192	122	6	with	with	ADP
dti-2192	122	7	tti	tti	PROPN
dti-2192	122	8	showed	show	VERB
dti-2192	122	9	a	a	DET
dti-2192	122	10	slight	slight	ADJ
dti-2192	122	11	reduction	reduction	NOUN
dti-2192	122	12	in	in	ADP
dti-2192	122	13	the	the	DET
dti-2192	122	14	lee	lee	PROPN
dti-2192	122	15	index	index	PROPN
dti-2192	122	16	,	,	PUNCT
dti-2192	122	17	which	which	PRON
dti-2192	122	18	,	,	PUNCT
dti-2192	122	19	although	although	SCONJ
dti-2192	122	20	not	not	PART
dti-2192	122	21	significant	significant	ADJ
dti-2192	122	22	,	,	PUNCT
dti-2192	122	23	was	be	AUX
dti-2192	122	24	important	important	ADJ
dti-2192	122	25	because	because	SCONJ
dti-2192	122	26	of	of	ADP
dti-2192	122	27	the	the	DET
dti-2192	122	28	consumption	consumption	NOUN
dti-2192	122	29	of	of	ADP
dti-2192	122	30	a	a	DET
dti-2192	122	31	diet	diet	NOUN
dti-2192	122	32	rich	rich	ADJ
dti-2192	122	33	in	in	ADP
dti-2192	122	34	ultraprocessed	ultraprocessed	ADJ
dti-2192	122	35	foods	food	NOUN
dti-2192	122	36	called	call	VERB
dti-2192	122	37	high	high	ADJ
dti-2192	122	38	glycemic	glycemic	ADJ
dti-2192	122	39	index	index	NOUN
dti-2192	122	40	and	and	CCONJ
dti-2192	122	41	glycemic	glycemic	ADJ
dti-2192	122	42	load	load	NOUN
dti-2192	122	43	(	(	PUNCT
dti-2192	122	44	hgli	hgli	NOUN
dti-2192	122	45	)	)	PUNCT
dti-2192	122	46	(	(	PUNCT
dti-2192	122	47	64	64	NUM
dti-2192	122	48	)	)	PUNCT
dti-2192	122	49	.	.	PUNCT
dti-2192	123	1	although	although	SCONJ
dti-2192	123	2	tti	tti	PROPN
dti-2192	123	3	did	do	AUX
dti-2192	123	4	not	not	PART
dti-2192	123	5	alter	alter	VERB
dti-2192	123	6	the	the	DET
dti-2192	123	7	plasma	plasma	NOUN
dti-2192	123	8	cck	cck	NOUN
dti-2192	123	9	,	,	PUNCT
dti-2192	123	10	it	it	PRON
dti-2192	123	11	decreased	decrease	VERB
dti-2192	123	12	the	the	DET
dti-2192	123	13	expression	expression	NOUN
dti-2192	123	14	of	of	ADP
dti-2192	123	15	the	the	DET
dti-2192	123	16	cck-1r	cck-1r	ADJ
dti-2192	123	17	gene	gene	NOUN
dti-2192	123	18	and	and	CCONJ
dti-2192	123	19	plasma	plasma	NOUN
dti-2192	123	20	leptin	leptin	NOUN
dti-2192	123	21	in	in	ADP
dti-2192	123	22	animals	animal	NOUN
dti-2192	123	23	with	with	ADP
dti-2192	123	24	obesity	obesity	NOUN
dti-2192	123	25	compared	compare	VERB
dti-2192	123	26	to	to	ADP
dti-2192	123	27	the	the	DET
dti-2192	123	28	group	group	NOUN
dti-2192	123	29	with	with	ADP
dti-2192	123	30	obesity	obesity	NOUN
dti-2192	123	31	without	without	ADP
dti-2192	123	32	treatment	treatment	NOUN
dti-2192	123	33	(	(	PUNCT
dti-2192	123	34	63	63	NUM
dti-2192	123	35	)	)	PUNCT
dti-2192	123	36	.	.	PUNCT
dti-2192	124	1	tti	tti	PROPN
dti-2192	124	2	is	be	AUX
dti-2192	124	3	characterized	characterize	VERB
dti-2192	124	4	as	as	ADP
dti-2192	124	5	a	a	DET
dti-2192	124	6	protein	protein	NOUN
dti-2192	124	7	isolate	isolate	NOUN
dti-2192	124	8	with	with	ADP
dti-2192	124	9	high	high	ADJ
dti-2192	124	10	inhibitory	inhibitory	ADJ
dti-2192	124	11	activity	activity	NOUN
dti-2192	124	12	for	for	ADP
dti-2192	124	13	trypsin	trypsin	NOUN
dti-2192	124	14	,	,	PUNCT
dti-2192	124	15	obtained	obtain	VERB
dti-2192	124	16	in	in	ADP
dti-2192	124	17	a	a	DET
dti-2192	124	18	process	process	NOUN
dti-2192	124	19	that	that	PRON
dti-2192	124	20	generates	generate	VERB
dti-2192	124	21	enrichment	enrichment	NOUN
dti-2192	124	22	of	of	ADP
dti-2192	124	23	this	this	DET
dti-2192	124	24	protein	protein	NOUN
dti-2192	124	25	,	,	PUNCT
dti-2192	124	26	but	but	CCONJ
dti-2192	124	27	not	not	PART
dti-2192	124	28	its	its	PRON
dti-2192	124	29	purification	purification	NOUN
dti-2192	124	30	(	(	PUNCT
dti-2192	124	31	61	61	NUM
dti-2192	124	32	)	)	PUNCT
dti-2192	124	33	.	.	PUNCT
dti-2192	125	1	therefore	therefore	ADV
dti-2192	125	2	,	,	PUNCT
dti-2192	125	3	it	it	PRON
dti-2192	125	4	is	be	AUX
dti-2192	125	5	possible	possible	ADJ
dti-2192	125	6	that	that	SCONJ
dti-2192	125	7	other	other	ADJ
dti-2192	125	8	molecules	molecule	NOUN
dti-2192	125	9	can	can	AUX
dti-2192	125	10	influence	influence	VERB
dti-2192	125	11	the	the	DET
dti-2192	125	12	biochemical	biochemical	ADJ
dti-2192	125	13	and	and	CCONJ
dti-2192	125	14	bioactive	bioactive	ADJ
dti-2192	125	15	characteristics	characteristic	NOUN
dti-2192	125	16	of	of	ADP
dti-2192	125	17	tti	tti	PROPN
dti-2192	125	18	.	.	PUNCT
dti-2192	126	1	due	due	ADP
dti-2192	126	2	to	to	ADP
dti-2192	126	3	the	the	DET
dti-2192	126	4	many	many	ADJ
dti-2192	126	5	biological	biological	ADJ
dti-2192	126	6	functions	function	NOUN
dti-2192	126	7	of	of	ADP
dti-2192	126	8	tti	tti	PROPN
dti-2192	126	9	in	in	ADP
dti-2192	126	10	the	the	DET
dti-2192	126	11	context	context	NOUN
dti-2192	126	12	of	of	ADP
dti-2192	126	13	obesity	obesity	NOUN
dti-2192	126	14	,	,	PUNCT
dti-2192	126	15	new	new	ADJ
dti-2192	126	16	technologies	technology	NOUN
dti-2192	126	17	that	that	PRON
dti-2192	126	18	could	could	AUX
dti-2192	126	19	potentialize	potentialize	VERB
dti-2192	126	20	these	these	DET
dti-2192	126	21	functions	function	NOUN
dti-2192	126	22	were	be	AUX
dti-2192	126	23	assessed	assess	VERB
dti-2192	126	24	.	.	PUNCT
dti-2192	127	1	nanotechnology	nanotechnology	NOUN
dti-2192	127	2	,	,	PUNCT
dti-2192	127	3	through	through	ADP
dti-2192	127	4	nanoencapsulation	nanoencapsulation	NOUN
dti-2192	127	5	,	,	PUNCT
dti-2192	127	6	can	can	AUX
dti-2192	127	7	promote	promote	VERB
dti-2192	127	8	the	the	DET
dti-2192	127	9	protection	protection	NOUN
dti-2192	127	10	of	of	ADP
dti-2192	127	11	bioactive	bioactive	ADJ
dti-2192	127	12	substances	substance	NOUN
dti-2192	127	13	in	in	ADP
dti-2192	127	14	oral	oral	ADJ
dti-2192	127	15	administration	administration	NOUN
dti-2192	127	16	,	,	PUNCT
dti-2192	127	17	which	which	PRON
dti-2192	127	18	exposes	expose	VERB
dti-2192	127	19	these	these	DET
dti-2192	127	20	molecules	molecule	NOUN
dti-2192	127	21	to	to	ADP
dti-2192	127	22	digestive	digestive	ADJ
dti-2192	127	23	processes	process	NOUN
dti-2192	127	24	,	,	PUNCT
dti-2192	127	25	compromising	compromise	VERB
dti-2192	127	26	active	active	ADJ
dti-2192	127	27	sites	site	NOUN
dti-2192	127	28	essential	essential	ADJ
dti-2192	127	29	to	to	ADP
dti-2192	127	30	biological	biological	ADJ
dti-2192	127	31	activity	activity	NOUN
dti-2192	127	32	.	.	PUNCT
dti-2192	128	1	in	in	ADP
dti-2192	128	2	addition	addition	NOUN
dti-2192	128	3	,	,	PUNCT
dti-2192	128	4	nanoencapsulation	nanoencapsulation	NOUN
dti-2192	128	5	provides	provide	VERB
dti-2192	128	6	controlled	control	VERB
dti-2192	128	7	release	release	NOUN
dti-2192	128	8	at	at	ADP
dti-2192	128	9	a	a	DET
dti-2192	128	10	specific	specific	ADJ
dti-2192	128	11	target	target	NOUN
dti-2192	128	12	and	and	CCONJ
dti-2192	128	13	further	further	ADJ
dti-2192	128	14	intensification	intensification	NOUN
dti-2192	128	15	of	of	ADP
dti-2192	128	16	the	the	DET
dti-2192	128	17	biological	biological	ADJ
dti-2192	128	18	effect	effect	NOUN
dti-2192	128	19	(	(	PUNCT
dti-2192	128	20	65	65	NUM
dti-2192	128	21	)	)	PUNCT
dti-2192	128	22	.	.	PUNCT
dti-2192	129	1	thus	thus	ADV
dti-2192	129	2	,	,	PUNCT
dti-2192	129	3	tti	tti	PROPN
dti-2192	129	4	was	be	AUX
dti-2192	129	5	nanoencapsulated	nanoencapsulate	VERB
dti-2192	129	6	to	to	PART
dti-2192	129	7	increase	increase	VERB
dti-2192	129	8	the	the	DET
dti-2192	129	9	efficiency	efficiency	NOUN
dti-2192	129	10	and	and	CCONJ
dti-2192	129	11	stability	stability	NOUN
dti-2192	129	12	of	of	ADP
dti-2192	129	13	antitrypsin	antitrypsin	NOUN
dti-2192	129	14	activity	activity	NOUN
dti-2192	129	15	.	.	PUNCT
dti-2192	130	1	the	the	DET
dti-2192	130	2	isolated	isolated	ADJ
dti-2192	130	3	and	and	CCONJ
dti-2192	130	4	conjugated	conjugated	ADJ
dti-2192	130	5	effects	effect	NOUN
dti-2192	130	6	of	of	ADP
dti-2192	130	7	chitosan	chitosan	NOUN
dti-2192	130	8	and	and	CCONJ
dti-2192	130	9	isolated	isolate	VERB
dti-2192	130	10	whey	whey	PROPN
dti-2192	130	11	protein	protein	NOUN
dti-2192	130	12	on	on	ADP
dti-2192	130	13	incorporation	incorporation	NOUN
dti-2192	130	14	,	,	PUNCT
dti-2192	130	15	antitrypsin	antitrypsin	NOUN
dti-2192	130	16	activity	activity	NOUN
dti-2192	130	17	,	,	PUNCT
dti-2192	130	18	and	and	CCONJ
dti-2192	130	19	tti	tti	PROPN
dti-2192	130	20	stability	stability	NOUN
dti-2192	130	21	at	at	ADP
dti-2192	130	22	different	different	ADJ
dti-2192	130	23	temperatures	temperature	NOUN
dti-2192	130	24	and	and	CCONJ
dti-2192	130	25	ph	ph	ADJ
dti-2192	130	26	conditions	condition	NOUN
dti-2192	130	27	were	be	AUX
dti-2192	130	28	investigated	investigate	VERB
dti-2192	130	29	.	.	PUNCT
dti-2192	131	1	the	the	DET
dti-2192	131	2	combination	combination	NOUN
dti-2192	131	3	of	of	ADP
dti-2192	131	4	chitosan	chitosan	NOUN
dti-2192	131	5	and	and	CCONJ
dti-2192	131	6	isolated	isolate	VERB
dti-2192	131	7	whey	whey	PROPN
dti-2192	131	8	protein	protein	NOUN
dti-2192	131	9	(	(	PUNCT
dti-2192	131	10	ecw	ecw	PROPN
dti-2192	131	11	)	)	PUNCT
dti-2192	131	12	formed	form	VERB
dti-2192	131	13	nanoparticles	nanoparticle	NOUN
dti-2192	131	14	(	(	PUNCT
dti-2192	131	15	109	109	NUM
dti-2192	131	16	nm	nm	NOUN
dti-2192	131	17	)	)	PUNCT
dti-2192	131	18	,	,	PUNCT
dti-2192	131	19	promoted	promote	VERB
dti-2192	131	20	a	a	DET
dti-2192	131	21	reduction	reduction	NOUN
dti-2192	131	22	in	in	ADP
dti-2192	131	23	the	the	DET
dti-2192	131	24	half	half	ADJ
dti-2192	131	25	maximal	maximal	ADJ
dti-2192	131	26	inhibitory	inhibitory	ADJ
dti-2192	131	27	concentration	concentration	NOUN
dti-2192	131	28	(	(	PUNCT
dti-2192	131	29	ic50	ic50	PROPN
dti-2192	131	30	;	;	PUNCT
dti-2192	131	31	0.05	0.05	NUM
dti-2192	131	32	mg	mg	NOUN
dti-2192	131	33	)	)	PUNCT
dti-2192	131	34	compared	compare	VERB
dti-2192	131	35	to	to	ADP
dti-2192	131	36	pure	pure	ADJ
dti-2192	131	37	tti	tti	PROPN
dti-2192	131	38	(	(	PUNCT
dti-2192	131	39	0.21	0.21	NUM
dti-2192	131	40	mg	mg	NUM
dti-2192	131	41	)	)	PUNCT
dti-2192	131	42	,	,	PUNCT
dti-2192	131	43	and	and	CCONJ
dti-2192	131	44	preserved	preserve	VERB
dti-2192	131	45	antitrypsin	antitrypsin	NOUN
dti-2192	131	46	activity	activity	NOUN
dti-2192	131	47	up	up	ADP
dti-2192	131	48	to	to	PART
dti-2192	131	49	80	80	NUM
dti-2192	131	50	°	°	NOUN
dti-2192	131	51	c	c	X
dti-2192	131	52	(	(	PUNCT
dti-2192	131	53	35.0	35.0	NUM
dti-2192	131	54	%	%	NOUN
dti-2192	131	55	[	[	X
dti-2192	131	56	3.74	3.74	NUM
dti-2192	131	57	]	]	PUNCT
dti-2192	131	58	)	)	PUNCT
dti-2192	131	59	compared	compare	VERB
dti-2192	131	60	to	to	ADP
dti-2192	131	61	isolated	isolated	ADJ
dti-2192	131	62	agents	agent	NOUN
dti-2192	131	63	and	and	CCONJ
dti-2192	131	64	tti	tti	PROPN
dti-2192	131	65	,	,	PUNCT
dti-2192	131	66	which	which	PRON
dti-2192	131	67	have	have	VERB
dti-2192	131	68	no	no	DET
dti-2192	131	69	inhibitory	inhibitory	ADJ
dti-2192	131	70	activity	activity	NOUN
dti-2192	131	71	.	.	PUNCT
dti-2192	132	1	besides	besides	SCONJ
dti-2192	132	2	,	,	PUNCT
dti-2192	132	3	the	the	DET
dti-2192	132	4	nanoparticles	nanoparticle	NOUN
dti-2192	132	5	showed	show	VERB
dti-2192	132	6	stability	stability	NOUN
dti-2192	132	7	under	under	ADP
dti-2192	132	8	different	different	ADJ
dti-2192	132	9	ph	ph	ADJ
dti-2192	132	10	conditions	condition	NOUN
dti-2192	132	11	.	.	PUNCT
dti-2192	133	1	thus	thus	ADV
dti-2192	133	2	,	,	PUNCT
dti-2192	133	3	ecw	ecw	PROPN
dti-2192	133	4	proved	prove	VERB
dti-2192	133	5	to	to	PART
dti-2192	133	6	be	be	AUX
dti-2192	133	7	an	an	DET
dti-2192	133	8	essential	essential	ADJ
dti-2192	133	9	strategy	strategy	NOUN
dti-2192	133	10	to	to	PART
dti-2192	133	11	improve	improve	VERB
dti-2192	133	12	the	the	DET
dti-2192	133	13	function	function	NOUN
dti-2192	133	14	and	and	CCONJ
dti-2192	133	15	stability	stability	NOUN
dti-2192	133	16	of	of	ADP
dti-2192	133	17	tti	tti	PROPN
dti-2192	133	18	(	(	PUNCT
dti-2192	133	19	66	66	NUM
dti-2192	133	20	)	)	PUNCT
dti-2192	133	21	.	.	PUNCT
dti-2192	134	1	to	to	PART
dti-2192	134	2	assess	assess	VERB
dti-2192	134	3	the	the	DET
dti-2192	134	4	safety	safety	NOUN
dti-2192	134	5	of	of	ADP
dti-2192	134	6	administration	administration	NOUN
dti-2192	134	7	by	by	ADP
dti-2192	134	8	gavage	gavage	NOUN
dti-2192	134	9	in	in	ADP
dti-2192	134	10	addition	addition	NOUN
dti-2192	134	11	to	to	ADP
dti-2192	134	12	maintaining	maintain	VERB
dti-2192	134	13	the	the	DET
dti-2192	134	14	inhibitory	inhibitory	ADJ
dti-2192	134	15	activity	activity	NOUN
dti-2192	134	16	,	,	PUNCT
dti-2192	134	17	the	the	DET
dti-2192	134	18	encapsulated	encapsulate	VERB
dti-2192	134	19	tti	tti	PROPN
dti-2192	134	20	(	(	PUNCT
dti-2192	134	21	ecw	ecw	PROPN
dti-2192	134	22	)	)	PUNCT
dti-2192	134	23	was	be	AUX
dti-2192	134	24	evaluated	evaluate	VERB
dti-2192	134	25	in	in	ADP
dti-2192	134	26	a	a	DET
dti-2192	134	27	preclinical	preclinical	ADJ
dti-2192	134	28	obesity	obesity	NOUN
dti-2192	134	29	study	study	NOUN
dti-2192	134	30	.	.	PUNCT
dti-2192	135	1	costa	costa	PROPN
dti-2192	135	2	(	(	PUNCT
dti-2192	135	3	67	67	NUM
dti-2192	135	4	)	)	PUNCT
dti-2192	135	5	also	also	ADV
dti-2192	135	6	assessed	assess	VERB
dti-2192	135	7	cytotoxicity	cytotoxicity	NOUN
dti-2192	135	8	using	use	VERB
dti-2192	135	9	the	the	DET
dti-2192	135	10	caco-2	caco-2	NUM
dti-2192	135	11	and	and	CCONJ
dti-2192	135	12	ccd18co	ccd18co	NOUN
dti-2192	135	13	strains	strain	NOUN
dti-2192	135	14	(	(	PUNCT
dti-2192	135	15	human	human	ADJ
dti-2192	135	16	intestinal	intestinal	ADJ
dti-2192	135	17	cells	cell	NOUN
dti-2192	135	18	)	)	PUNCT
dti-2192	135	19	.	.	PUNCT
dti-2192	136	1	the	the	DET
dti-2192	136	2	cytotoxicity	cytotoxicity	NOUN
dti-2192	136	3	assay	assay	NOUN
dti-2192	136	4	exceeded	exceed	VERB
dti-2192	136	5	70	70	NUM
dti-2192	136	6	%	%	NOUN
dti-2192	136	7	cell	cell	NOUN
dti-2192	136	8	viability	viability	NOUN
dti-2192	136	9	for	for	ADP
dti-2192	136	10	caco-2	caco-2	NUM
dti-2192	136	11	and	and	CCONJ
dti-2192	136	12	ccd-18co	ccd-18co	NUM
dti-2192	136	13	when	when	SCONJ
dti-2192	136	14	exposed	expose	VERB
dti-2192	136	15	to	to	ADP
dti-2192	136	16	different	different	ADJ
dti-2192	136	17	concentrations	concentration	NOUN
dti-2192	136	18	of	of	ADP
dti-2192	136	19	ecw	ecw	PROPN
dti-2192	136	20	.	.	PUNCT
dti-2192	137	1	for	for	ADP
dti-2192	137	2	the	the	DET
dti-2192	137	3	subacute	subacute	ADJ
dti-2192	137	4	blood	blood	NOUN
dti-2192	137	5	toxicity	toxicity	NOUN
dti-2192	137	6	of	of	ADP
dti-2192	137	7	the	the	DET
dti-2192	137	8	bioactive	bioactive	PROPN
dti-2192	137	9	dose	dose	PROPN
dti-2192	137	10	of	of	ADP
dti-2192	137	11	ecw	ecw	PROPN
dti-2192	137	12	,	,	PUNCT
dti-2192	137	13	through	through	ADP
dti-2192	137	14	a	a	DET
dti-2192	137	15	complete	complete	ADJ
dti-2192	137	16	blood	blood	NOUN
dti-2192	137	17	count	count	NOUN
dti-2192	137	18	,	,	PUNCT
dti-2192	137	19	liver	liver	NOUN
dti-2192	137	20	,	,	PUNCT
dti-2192	137	21	and	and	CCONJ
dti-2192	137	22	kidney	kidney	NOUN
dti-2192	137	23	function	function	NOUN
dti-2192	137	24	,	,	PUNCT
dti-2192	137	25	there	there	PRON
dti-2192	137	26	was	be	VERB
dti-2192	137	27	an	an	DET
dti-2192	137	28	absence	absence	NOUN
dti-2192	137	29	of	of	ADP
dti-2192	137	30	subacute	subacute	ADJ
dti-2192	137	31	blood	blood	NOUN
dti-2192	137	32	toxicity	toxicity	NOUN
dti-2192	137	33	,	,	PUNCT
dti-2192	137	34	demonstrated	demonstrate	VERB
dti-2192	137	35	by	by	ADP
dti-2192	137	36	the	the	DET
dti-2192	137	37	lack	lack	NOUN
dti-2192	137	38	of	of	ADP
dti-2192	137	39	toxic	toxic	ADJ
dti-2192	137	40	effects	effect	NOUN
dti-2192	137	41	on	on	ADP
dti-2192	137	42	the	the	DET
dti-2192	137	43	biochemical	biochemical	ADJ
dti-2192	137	44	parameters	parameter	NOUN
dti-2192	137	45	evaluated	evaluate	VERB
dti-2192	137	46	.	.	PUNCT
dti-2192	138	1	considering	consider	VERB
dti-2192	138	2	that	that	SCONJ
dti-2192	138	3	ecw	ecw	PROPN
dti-2192	138	4	proved	prove	VERB
dti-2192	138	5	to	to	PART
dti-2192	138	6	be	be	AUX
dti-2192	138	7	safe	safe	ADJ
dti-2192	138	8	in	in	ADP
dti-2192	138	9	the	the	DET
dti-2192	138	10	face	face	NOUN
dti-2192	138	11	of	of	ADP
dti-2192	138	12	the	the	DET
dti-2192	138	13	parameters	parameter	NOUN
dti-2192	138	14	evaluated	evaluate	VERB
dti-2192	138	15	,	,	PUNCT
dti-2192	138	16	its	its	PRON
dti-2192	138	17	biological	biological	ADJ
dti-2192	138	18	activity	activity	NOUN
dti-2192	138	19	was	be	AUX
dti-2192	138	20	tested	test	VERB
dti-2192	138	21	after	after	ADP
dti-2192	138	22	encapsulation	encapsulation	NOUN
dti-2192	138	23	(	(	PUNCT
dti-2192	138	24	68	68	NUM
dti-2192	138	25	)	)	PUNCT
dti-2192	138	26	.	.	PUNCT
dti-2192	139	1	the	the	DET
dti-2192	139	2	nanoencapsulated	nanoencapsulate	VERB
dti-2192	139	3	tti	tti	PROPN
dti-2192	139	4	was	be	AUX
dti-2192	139	5	also	also	ADV
dti-2192	139	6	offered	offer	VERB
dti-2192	139	7	by	by	ADP
dti-2192	139	8	gavage	gavage	NOUN
dti-2192	139	9	in	in	ADP
dti-2192	139	10	a	a	DET
dti-2192	139	11	preclinical	preclinical	ADJ
dti-2192	139	12	obesity	obesity	NOUN
dti-2192	139	13	model	model	NOUN
dti-2192	139	14	to	to	PART
dti-2192	139	15	test	test	VERB
dti-2192	139	16	whether	whether	SCONJ
dti-2192	139	17	the	the	DET
dti-2192	139	18	isolated	isolated	ADJ
dti-2192	139	19	inhibitor	inhibitor	NOUN
dti-2192	139	20	would	would	AUX
dti-2192	139	21	maintain	maintain	VERB
dti-2192	139	22	its	its	PRON
dti-2192	139	23	modulating	modulate	VERB
dti-2192	139	24	properties	property	NOUN
dti-2192	139	25	on	on	ADP
dti-2192	139	26	the	the	DET
dti-2192	139	27	altered	altered	ADJ
dti-2192	139	28	biochemical	biochemical	ADJ
dti-2192	139	29	parameters	parameter	NOUN
dti-2192	139	30	of	of	ADP
dti-2192	139	31	the	the	DET
dti-2192	139	32	experimental	experimental	ADJ
dti-2192	139	33	model	model	NOUN
dti-2192	139	34	used	use	VERB
dti-2192	139	35	.	.	PUNCT
dti-2192	140	1	the	the	DET
dti-2192	140	2	biological	biological	ADJ
dti-2192	140	3	activity	activity	NOUN
dti-2192	140	4	was	be	AUX
dti-2192	140	5	maintained	maintain	VERB
dti-2192	140	6	,	,	PUNCT
dti-2192	140	7	with	with	ADP
dti-2192	140	8	emphasis	emphasis	NOUN
dti-2192	140	9	on	on	ADP
dti-2192	140	10	ecw	ecw	PROPN
dti-2192	140	11	,	,	PUNCT
dti-2192	140	12	which	which	PRON
dti-2192	140	13	significantly	significantly	ADV
dti-2192	140	14	reduced	reduce	VERB
dti-2192	140	15	blood	blood	NOUN
dti-2192	140	16	glucose	glucose	NOUN
dti-2192	140	17	,	,	PUNCT
dti-2192	140	18	homeostatic	homeostatic	ADJ
dti-2192	140	19	model	model	NOUN
dti-2192	140	20	assessment	assessment	NOUN
dti-2192	140	21	of	of	ADP
dti-2192	140	22	insulin	insulin	NOUN
dti-2192	140	23	resistance	resistance	NOUN
dti-2192	140	24	(	(	PUNCT
dti-2192	140	25	homa	homa	NOUN
dti-2192	140	26	-	-	PUNCT
dti-2192	140	27	ir	ir	NOUN
dti-2192	140	28	)	)	PUNCT
dti-2192	140	29	,	,	PUNCT
dti-2192	140	30	and	and	CCONJ
dti-2192	140	31	raised	raise	VERB
dti-2192	140	32	high	high	ADJ
dti-2192	140	33	-	-	PUNCT
dti-2192	140	34	density	density	NOUN
dti-2192	140	35	lipoprotein	lipoprotein	ADJ
dti-2192	140	36	cholesterol	cholesterol	NOUN
dti-2192	140	37	(	(	PUNCT
dti-2192	140	38	hdl	hdl	NOUN
dti-2192	140	39	-	-	PUNCT
dti-2192	140	40	c	c	NOUN
dti-2192	140	41	)	)	PUNCT
dti-2192	140	42	,	,	PUNCT
dti-2192	140	43	in	in	ADP
dti-2192	140	44	addition	addition	NOUN
dti-2192	140	45	to	to	ADP
dti-2192	140	46	possibly	possibly	ADV
dti-2192	140	47	favoring	favor	VERB
dti-2192	140	48	greater	great	ADJ
dti-2192	140	49	protection	protection	NOUN
dti-2192	140	50	to	to	ADP
dti-2192	140	51	pancreatic	pancreatic	ADJ
dti-2192	140	52	tissue	tissue	NOUN
dti-2192	140	53	.	.	PUNCT
dti-2192	141	1	the	the	DET
dti-2192	141	2	purification	purification	NOUN
dti-2192	141	3	of	of	ADP
dti-2192	141	4	these	these	DET
dti-2192	141	5	inhibitors	inhibitor	NOUN
dti-2192	141	6	is	be	AUX
dti-2192	141	7	a	a	DET
dti-2192	141	8	necessary	necessary	ADJ
dti-2192	141	9	and	and	CCONJ
dti-2192	141	10	critical	critical	ADJ
dti-2192	141	11	step	step	NOUN
dti-2192	141	12	to	to	PART
dti-2192	141	13	define	define	VERB
dti-2192	141	14	their	their	PRON
dti-2192	141	15	structural	structural	ADJ
dti-2192	141	16	characteristics	characteristic	NOUN
dti-2192	141	17	and	and	CCONJ
dti-2192	141	18	specificity	specificity	NOUN
dti-2192	141	19	of	of	ADP
dti-2192	141	20	binding	bind	VERB
dti-2192	141	21	to	to	ADP
dti-2192	141	22	other	other	ADJ
dti-2192	141	23	molecules	molecule	NOUN
dti-2192	141	24	.	.	PUNCT
dti-2192	142	1	isolating	isolate	VERB
dti-2192	142	2	these	these	DET
dti-2192	142	3	proteins	protein	NOUN
dti-2192	142	4	from	from	ADP
dti-2192	142	5	all	all	DET
dti-2192	142	6	other	other	ADJ
dti-2192	142	7	proteins	protein	NOUN
dti-2192	142	8	that	that	PRON
dti-2192	142	9	are	be	AUX
dti-2192	142	10	present	present	ADJ
dti-2192	142	11	in	in	ADP
dti-2192	142	12	the	the	DET
dti-2192	142	13	same	same	ADJ
dti-2192	142	14	biological	biological	ADJ
dti-2192	142	15	source	source	NOUN
dti-2192	142	16	is	be	AUX
dti-2192	142	17	difficult	difficult	ADJ
dti-2192	142	18	because	because	SCONJ
dti-2192	142	19	trypsin	trypsin	NOUN
dti-2192	142	20	inhibitors	inhibitor	NOUN
dti-2192	142	21	have	have	VERB
dti-2192	142	22	great	great	ADJ
dti-2192	142	23	molecular	molecular	ADJ
dti-2192	142	24	diversity	diversity	NOUN
dti-2192	142	25	(	(	PUNCT
dti-2192	142	26	69	69	NUM
dti-2192	142	27	)	)	PUNCT
dti-2192	142	28	.	.	PUNCT
dti-2192	143	1	medeiros	medeiros	PROPN
dti-2192	143	2	et	et	PROPN
dti-2192	143	3	al	al	PROPN
dti-2192	143	4	(	(	PUNCT
dti-2192	143	5	70	70	NUM
dti-2192	143	6	)	)	PUNCT
dti-2192	143	7	described	describe	VERB
dti-2192	143	8	the	the	DET
dti-2192	143	9	tti	tti	PROPN
dti-2192	143	10	purification	purification	NOUN
dti-2192	143	11	process	process	NOUN
dti-2192	143	12	,	,	PUNCT
dti-2192	143	13	obtaining	obtain	VERB
dti-2192	143	14	a	a	DET
dti-2192	143	15	molecule	molecule	NOUN
dti-2192	143	16	with	with	ADP
dti-2192	143	17	100	100	NUM
dti-2192	143	18	%	%	NOUN
dti-2192	143	19	inhibition	inhibition	NOUN
dti-2192	143	20	for	for	ADP
dti-2192	143	21	trypsin	trypsin	NOUN
dti-2192	143	22	(	(	PUNCT
dti-2192	143	23	ptti	ptti	NOUN
dti-2192	143	24	)	)	PUNCT
dti-2192	143	25	,	,	PUNCT
dti-2192	143	26	heat	heat	NOUN
dti-2192	143	27	resistant	resistant	ADJ
dti-2192	143	28	and	and	CCONJ
dti-2192	143	29	with	with	ADP
dti-2192	143	30	a	a	DET
dti-2192	143	31	partially	partially	ADV
dti-2192	143	32	identified	identify	VERB
dti-2192	143	33	amino	amino	NOUN
dti-2192	143	34	acid	acid	NOUN
dti-2192	143	35	sequence	sequence	NOUN
dti-2192	143	36	(	(	PUNCT
dti-2192	143	37	currently	currently	ADV
dti-2192	143	38	complete	complete	ADJ
dti-2192	143	39	and	and	CCONJ
dti-2192	143	40	with	with	ADP
dti-2192	143	41	structural	structural	ADJ
dti-2192	143	42	modeling	modeling	NOUN
dti-2192	143	43	—	—	PUNCT
dti-2192	143	44	unpublished	unpublished	ADJ
dti-2192	143	45	data	datum	NOUN
dti-2192	143	46	)	)	PUNCT
dti-2192	143	47	,	,	PUNCT
dti-2192	143	48	which	which	PRON
dti-2192	143	49	had	have	VERB
dti-2192	143	50	high	high	ADJ
dti-2192	143	51	homology	homology	NOUN
dti-2192	143	52	with	with	ADP
dti-2192	143	53	other	other	ADJ
dti-2192	143	54	trypsin	trypsin	NOUN
dti-2192	143	55	inhibitors	inhibitor	NOUN
dti-2192	143	56	of	of	ADP
dti-2192	143	57	the	the	DET
dti-2192	143	58	kunitz	kunitz	PROPN
dti-2192	143	59	family	family	PROPN
dti-2192	143	60	.	.	PUNCT
dti-2192	144	1	ptti	ptti	PROPN
dti-2192	144	2	also	also	ADV
dti-2192	144	3	did	do	AUX
dti-2192	144	4	not	not	PART
dti-2192	144	5	affect	affect	VERB
dti-2192	144	6	plasma	plasma	NOUN
dti-2192	144	7	cck	cck	ADJ
dti-2192	144	8	concentrations	concentration	NOUN
dti-2192	144	9	but	but	CCONJ
dti-2192	144	10	reduced	reduce	VERB
dti-2192	144	11	circulating	circulate	VERB
dti-2192	144	12	leptin	leptin	NOUN
dti-2192	144	13	concentrations	concentration	NOUN
dti-2192	144	14	in	in	ADP
dti-2192	144	15	animals	animal	NOUN
dti-2192	144	16	with	with	ADP
dti-2192	144	17	obesity	obesity	NOUN
dti-2192	144	18	at	at	ADP
dti-2192	144	19	a	a	DET
dti-2192	144	20	dose	dose	NOUN
dti-2192	144	21	of	of	ADP
dti-2192	144	22	730	730	NUM
dti-2192	144	23	μg	μg	PROPN
dti-2192	144	24	/	/	SYM
dti-2192	144	25	kg	kg	PROPN
dti-2192	144	26	.	.	PUNCT
dti-2192	145	1	leptin	leptin	PROPN
dti-2192	145	2	is	be	AUX
dti-2192	145	3	an	an	DET
dti-2192	145	4	important	important	ADJ
dti-2192	145	5	hormone	hormone	NOUN
dti-2192	145	6	in	in	ADP
dti-2192	145	7	the	the	DET
dti-2192	145	8	energy	energy	NOUN
dti-2192	145	9	balance	balance	NOUN
dti-2192	145	10	,	,	PUNCT
dti-2192	145	11	which	which	PRON
dti-2192	145	12	is	be	AUX
dti-2192	145	13	elevated	elevate	VERB
dti-2192	145	14	in	in	ADP
dti-2192	145	15	individuals	individual	NOUN
dti-2192	145	16	with	with	ADP
dti-2192	145	17	obesity	obesity	NOUN
dti-2192	145	18	,	,	PUNCT
dti-2192	145	19	leading	lead	VERB
dti-2192	145	20	to	to	ADP
dti-2192	145	21	the	the	DET
dti-2192	145	22	development	development	NOUN
dti-2192	145	23	of	of	ADP
dti-2192	145	24	a	a	DET
dti-2192	145	25	resistance	resistance	NOUN
dti-2192	145	26	condition	condition	NOUN
dti-2192	145	27	(	(	PUNCT
dti-2192	145	28	70	70	NUM
dti-2192	145	29	)	)	PUNCT
dti-2192	145	30	.	.	PUNCT
dti-2192	146	1	the	the	DET
dti-2192	146	2	effect	effect	NOUN
dti-2192	146	3	of	of	ADP
dti-2192	146	4	the	the	DET
dti-2192	146	5	purified	purified	ADJ
dti-2192	146	6	trypsin	trypsin	NOUN
dti-2192	146	7	inhibitor	inhibitor	NOUN
dti-2192	146	8	tamarind	tamarind	NOUN
dti-2192	146	9	was	be	AUX
dti-2192	146	10	also	also	ADV
dti-2192	146	11	evaluated	evaluate	VERB
dti-2192	146	12	in	in	ADP
dti-2192	146	13	a	a	DET
dti-2192	146	14	model	model	NOUN
dti-2192	146	15	of	of	ADP
dti-2192	146	16	metabolic	metabolic	NOUN
dti-2192	146	17	changes	change	NOUN
dti-2192	146	18	in	in	ADP
dti-2192	146	19	wistar	wistar	PROPN
dti-2192	146	20	rats	rat	NOUN
dti-2192	146	21	with	with	ADP
dti-2192	146	22	obesity	obesity	NOUN
dti-2192	146	23	and	and	CCONJ
dti-2192	146	24	dyslipidemia	dyslipidemia	NOUN
dti-2192	146	25	.	.	PUNCT
dti-2192	147	1	obesity	obesity	NOUN
dti-2192	147	2	was	be	AUX
dti-2192	147	3	induced	induce	VERB
dti-2192	147	4	using	use	VERB
dti-2192	147	5	the	the	DET
dti-2192	147	6	hgli	hgli	NOUN
dti-2192	147	7	diet	diet	PROPN
dti-2192	147	8	(	(	PUNCT
dti-2192	147	9	64	64	NUM
dti-2192	147	10	)	)	PUNCT
dti-2192	147	11	.	.	PUNCT
dti-2192	148	1	the	the	DET
dti-2192	148	2	animals	animal	NOUN
dti-2192	148	3	treated	treat	VERB
dti-2192	148	4	with	with	ADP
dti-2192	148	5	ptti	ptti	NUM
dti-2192	148	6	at	at	ADP
dti-2192	148	7	a	a	DET
dti-2192	148	8	dose	dose	NOUN
dti-2192	148	9	of	of	ADP
dti-2192	148	10	730	730	NUM
dti-2192	148	11	μg	μg	PROPN
dti-2192	148	12	/	/	SYM
dti-2192	148	13	kg	kg	PROPN
dti-2192	148	14	had	have	AUX
dti-2192	148	15	significantly	significantly	ADV
dti-2192	148	16	lower	low	ADJ
dti-2192	148	17	food	food	NOUN
dti-2192	148	18	intake	intake	NOUN
dti-2192	148	19	than	than	ADP
dti-2192	148	20	the	the	DET
dti-2192	148	21	untreated	untreated	ADJ
dti-2192	148	22	group	group	NOUN
dti-2192	148	23	.	.	PUNCT
dti-2192	149	1	however	however	ADV
dti-2192	149	2	,	,	PUNCT
dti-2192	149	3	the	the	DET
dti-2192	149	4	groups	group	NOUN
dti-2192	149	5	did	do	AUX
dti-2192	149	6	not	not	PART
dti-2192	149	7	show	show	VERB
dti-2192	149	8	differences	difference	NOUN
dti-2192	149	9	in	in	ADP
dti-2192	149	10	weight	weight	NOUN
dti-2192	149	11	gain	gain	NOUN
dti-2192	149	12	.	.	PUNCT
dti-2192	150	1	ptti	ptti	PROPN
dti-2192	150	2	showed	show	VERB
dti-2192	150	3	great	great	ADJ
dti-2192	150	4	anti	anti	ADJ
dti-2192	150	5	-	-	ADJ
dti-2192	150	6	inflammatory	inflammatory	ADJ
dti-2192	150	7	potential	potential	NOUN
dti-2192	150	8	,	,	PUNCT
dti-2192	150	9	reducing	reduce	VERB
dti-2192	150	10	the	the	DET
dti-2192	150	11	relative	relative	ADJ
dti-2192	150	12	expression	expression	NOUN
dti-2192	150	13	of	of	ADP
dti-2192	150	14	tnf	tnf	PROPN
dti-2192	150	15	-	-	PUNCT
dti-2192	150	16	α	α	PROPN
dti-2192	150	17	messenger	messenger	NOUN
dti-2192	150	18	rna	rna	NOUN
dti-2192	150	19	and	and	CCONJ
dti-2192	150	20	positive	positive	ADJ
dti-2192	150	21	immunostaining	immunostaining	NOUN
dti-2192	150	22	in	in	ADP
dti-2192	150	23	adipocyte	adipocyte	ADJ
dti-2192	150	24	immunohistochemical	immunohistochemical	ADJ
dti-2192	150	25	analysis	analysis	NOUN
dti-2192	150	26	of	of	ADP
dti-2192	150	27	obese	obese	ADJ
dti-2192	150	28	animals	animal	NOUN
dti-2192	150	29	,	,	PUNCT
dti-2192	150	30	as	as	ADV
dti-2192	150	31	well	well	ADV
dti-2192	150	32	as	as	ADP
dti-2192	150	33	plasma	plasma	NOUN
dti-2192	150	34	cytokine	cytokine	NOUN
dti-2192	150	35	concentrations	concentration	NOUN
dti-2192	150	36	(	(	PUNCT
dti-2192	150	37	71	71	NUM
dti-2192	150	38	)	)	PUNCT
dti-2192	150	39	.	.	PUNCT
dti-2192	151	1	the	the	DET
dti-2192	151	2	anti	anti	ADJ
dti-2192	151	3	-	-	ADJ
dti-2192	151	4	inflammatory	inflammatory	ADJ
dti-2192	151	5	effects	effect	NOUN
dti-2192	151	6	of	of	ADP
dti-2192	151	7	the	the	DET
dti-2192	151	8	isolated	isolated	ADJ
dti-2192	151	9	or	or	CCONJ
dti-2192	151	10	purified	purified	ADJ
dti-2192	151	11	inhibitor	inhibitor	NOUN
dti-2192	151	12	on	on	ADP
dti-2192	151	13	adipose	adipose	ADJ
dti-2192	151	14	tissue	tissue	NOUN
dti-2192	151	15	were	be	AUX
dti-2192	151	16	observed	observe	VERB
dti-2192	151	17	regardless	regardless	ADV
dti-2192	151	18	of	of	ADP
dti-2192	151	19	weight	weight	NOUN
dti-2192	151	20	changes	change	NOUN
dti-2192	151	21	,	,	PUNCT
dti-2192	151	22	which	which	PRON
dti-2192	151	23	may	may	AUX
dti-2192	151	24	suggest	suggest	VERB
dti-2192	151	25	a	a	DET
dti-2192	151	26	direct	direct	ADJ
dti-2192	151	27	beneficial	beneficial	ADJ
dti-2192	151	28	effect	effect	NOUN
dti-2192	151	29	on	on	ADP
dti-2192	151	30	this	this	DET
dti-2192	151	31	tissue	tissue	NOUN
dti-2192	151	32	that	that	PRON
dti-2192	151	33	may	may	AUX
dti-2192	151	34	alter	alter	VERB
dti-2192	151	35	its	its	PRON
dti-2192	151	36	structure	structure	NOUN
dti-2192	151	37	.	.	PUNCT
dti-2192	152	1	this	this	DET
dti-2192	152	2	result	result	NOUN
dti-2192	152	3	shows	show	VERB
dti-2192	152	4	the	the	DET
dti-2192	152	5	potential	potential	NOUN
dti-2192	152	6	of	of	ADP
dti-2192	152	7	this	this	DET
dti-2192	152	8	molecule	molecule	NOUN
dti-2192	152	9	since	since	SCONJ
dti-2192	152	10	obesity	obesity	NOUN
dti-2192	152	11	is	be	AUX
dti-2192	152	12	classically	classically	ADV
dti-2192	152	13	considered	consider	VERB
dti-2192	152	14	a	a	DET
dti-2192	152	15	disease	disease	NOUN
dti-2192	152	16	that	that	PRON
dti-2192	152	17	induces	induce	VERB
dti-2192	152	18	a	a	DET
dti-2192	152	19	low	low	ADJ
dti-2192	152	20	grade	grade	NOUN
dti-2192	152	21	of	of	ADP
dti-2192	152	22	chronic	chronic	ADJ
dti-2192	152	23	inflammation	inflammation	NOUN
dti-2192	152	24	,	,	PUNCT
dti-2192	152	25	causing	cause	VERB
dti-2192	152	26	changes	change	NOUN
dti-2192	152	27	in	in	ADP
dti-2192	152	28	tissues	tissue	NOUN
dti-2192	152	29	,	,	PUNCT
dti-2192	152	30	notably	notably	ADV
dti-2192	152	31	the	the	DET
dti-2192	152	32	intestinal	intestinal	ADJ
dti-2192	152	33	mucosa	mucosa	NOUN
dti-2192	152	34	(	(	PUNCT
dti-2192	152	35	72	72	NUM
dti-2192	152	36	)	)	PUNCT
dti-2192	152	37	and	and	CCONJ
dti-2192	152	38	adipose	adipose	PRON
dti-2192	152	39	tissue	tissue	NOUN
dti-2192	152	40	(	(	PUNCT
dti-2192	152	41	73	73	NUM
dti-2192	152	42	)	)	PUNCT
dti-2192	152	43	.	.	PUNCT
dti-2192	153	1	due	due	ADP
dti-2192	153	2	to	to	ADP
dti-2192	153	3	these	these	DET
dti-2192	153	4	promising	promising	ADJ
dti-2192	153	5	biological	biological	ADJ
dti-2192	153	6	effects	effect	NOUN
dti-2192	153	7	and	and	CCONJ
dti-2192	153	8	safety	safety	NOUN
dti-2192	153	9	demonstrated	demonstrate	VERB
dti-2192	153	10	in	in	ADP
dti-2192	153	11	preclinical	preclinical	ADJ
dti-2192	153	12	studies	study	NOUN
dti-2192	153	13	with	with	ADP
dti-2192	153	14	partially	partially	ADV
dti-2192	153	15	purified	purify	VERB
dti-2192	153	16	tti	tti	PROPN
dti-2192	153	17	,	,	PUNCT
dti-2192	153	18	this	this	DET
dti-2192	153	19	inhibitor	inhibitor	NOUN
dti-2192	153	20	could	could	AUX
dti-2192	153	21	be	be	AUX
dti-2192	153	22	explored	explore	VERB
dti-2192	153	23	in	in	ADP
dti-2192	153	24	alternative	alternative	ADJ
dti-2192	153	25	obesity	obesity	NOUN
dti-2192	153	26	therapies	therapy	NOUN
dti-2192	153	27	.	.	PUNCT
dti-2192	154	1	the	the	DET
dti-2192	154	2	purification	purification	NOUN
dti-2192	154	3	process	process	NOUN
dti-2192	154	4	can	can	AUX
dti-2192	154	5	enhance	enhance	VERB
dti-2192	154	6	the	the	DET
dti-2192	154	7	functional	functional	ADJ
dti-2192	154	8	properties	property	NOUN
dti-2192	154	9	of	of	ADP
dti-2192	154	10	a	a	DET
dti-2192	154	11	molecule	molecule	NOUN
dti-2192	154	12	,	,	PUNCT
dti-2192	154	13	making	make	VERB
dti-2192	154	14	it	it	PRON
dti-2192	154	15	necessary	necessary	ADJ
dti-2192	154	16	to	to	PART
dti-2192	154	17	reassess	reassess	VERB
dti-2192	154	18	the	the	DET
dti-2192	154	19	safety	safety	NOUN
dti-2192	154	20	of	of	ADP
dti-2192	154	21	its	its	PRON
dti-2192	154	22	use	use	NOUN
dti-2192	154	23	.	.	PUNCT
dti-2192	155	1	at	at	ADP
dti-2192	155	2	a	a	DET
dti-2192	155	3	dose	dose	NOUN
dti-2192	155	4	approximately	approximately	ADV
dti-2192	155	5	thirty	thirty	NUM
dti-2192	155	6	times	time	NOUN
dti-2192	155	7	lower	low	ADJ
dti-2192	155	8	,	,	PUNCT
dti-2192	155	9	ptti	ptti	PROPN
dti-2192	155	10	performed	perform	VERB
dti-2192	155	11	the	the	DET
dti-2192	155	12	same	same	ADJ
dti-2192	155	13	biological	biological	ADJ
dti-2192	155	14	activities	activity	NOUN
dti-2192	155	15	as	as	ADP
dti-2192	155	16	tti	tti	PROPN
dti-2192	155	17	.	.	PUNCT
dti-2192	156	1	this	this	DET
dti-2192	156	2	morais	morais	PROPN
dti-2192	156	3	et	et	PROPN
dti-2192	156	4	al	al	PROPN
dti-2192	156	5	drug	drug	PROPN
dti-2192	156	6	target	target	NOUN
dti-2192	156	7	insights	insight	NOUN
dti-2192	156	8	2021	2021	NUM
dti-2192	156	9	;	;	PUNCT
dti-2192	156	10	15	15	NUM
dti-2192	156	11	:	:	SYM
dti-2192	156	12	9	9	NUM
dti-2192	156	13	©	©	PROPN
dti-2192	156	14	2021	2021	NUM
dti-2192	156	15	the	the	DET
dti-2192	156	16	authors	author	NOUN
dti-2192	156	17	.	.	PUNCT
dti-2192	157	1	published	publish	VERB
dti-2192	157	2	by	by	ADP
dti-2192	157	3	aboutscience	aboutscience	NOUN
dti-2192	157	4	www.aboutscience.eu	www.aboutscience.eu	NOUN
dti-2192	157	5	result	result	NOUN
dti-2192	157	6	emphasizes	emphasize	VERB
dti-2192	157	7	the	the	DET
dti-2192	157	8	need	need	NOUN
dti-2192	157	9	to	to	PART
dti-2192	157	10	assess	assess	VERB
dti-2192	157	11	whether	whether	SCONJ
dti-2192	157	12	its	its	PRON
dti-2192	157	13	use	use	NOUN
dti-2192	157	14	generated	generate	VERB
dti-2192	157	15	harmful	harmful	ADJ
dti-2192	157	16	effects	effect	NOUN
dti-2192	157	17	on	on	ADP
dti-2192	157	18	the	the	DET
dti-2192	157	19	liver	liver	NOUN
dti-2192	157	20	,	,	PUNCT
dti-2192	157	21	a	a	DET
dti-2192	157	22	target	target	NOUN
dti-2192	157	23	tissue	tissue	NOUN
dti-2192	157	24	in	in	ADP
dti-2192	157	25	toxicity	toxicity	NOUN
dti-2192	157	26	studies	study	NOUN
dti-2192	157	27	;	;	PUNCT
dti-2192	157	28	pancreas	pancrea	NOUN
dti-2192	157	29	,	,	PUNCT
dti-2192	157	30	a	a	DET
dti-2192	157	31	classically	classically	ADV
dti-2192	157	32	affected	affect	VERB
dti-2192	157	33	organ	organ	NOUN
dti-2192	157	34	by	by	ADP
dti-2192	157	35	trypsin	trypsin	NOUN
dti-2192	157	36	inhibitors	inhibitor	NOUN
dti-2192	157	37	;	;	PUNCT
dti-2192	157	38	adipose	adipose	ADJ
dti-2192	157	39	tissue	tissue	NOUN
dti-2192	157	40	,	,	PUNCT
dti-2192	157	41	where	where	SCONJ
dti-2192	157	42	ptti	ptti	NOUN
dti-2192	157	43	,	,	PUNCT
dti-2192	157	44	in	in	ADP
dti-2192	157	45	previous	previous	ADJ
dti-2192	157	46	studies	study	NOUN
dti-2192	157	47	,	,	PUNCT
dti-2192	157	48	has	have	AUX
dti-2192	157	49	shown	show	VERB
dti-2192	157	50	anti	anti	ADJ
dti-2192	157	51	-	-	ADJ
dti-2192	157	52	inflammatory	inflammatory	ADJ
dti-2192	157	53	effects	effect	NOUN
dti-2192	157	54	;	;	PUNCT
dti-2192	157	55	and	and	CCONJ
dti-2192	157	56	intestine	intestine	VERB
dti-2192	157	57	,	,	PUNCT
dti-2192	157	58	a	a	DET
dti-2192	157	59	potential	potential	ADJ
dti-2192	157	60	site	site	NOUN
dti-2192	157	61	of	of	ADP
dti-2192	157	62	action	action	NOUN
dti-2192	157	63	that	that	PRON
dti-2192	157	64	has	have	AUX
dti-2192	157	65	not	not	PART
dti-2192	157	66	yet	yet	ADV
dti-2192	157	67	been	be	AUX
dti-2192	157	68	studied	study	VERB
dti-2192	157	69	.	.	PUNCT
dti-2192	158	1	trypsin	trypsin	NOUN
dti-2192	158	2	inhibitors	inhibitor	NOUN
dti-2192	158	3	have	have	VERB
dti-2192	158	4	well	well	ADV
dti-2192	158	5	-	-	PUNCT
dti-2192	158	6	reported	report	VERB
dti-2192	158	7	deleterious	deleterious	ADJ
dti-2192	158	8	effects	effect	NOUN
dti-2192	158	9	.	.	PUNCT
dti-2192	159	1	evidence	evidence	NOUN
dti-2192	159	2	has	have	AUX
dti-2192	159	3	shown	show	VERB
dti-2192	159	4	impaired	impaired	ADJ
dti-2192	159	5	growth	growth	NOUN
dti-2192	159	6	due	due	ADP
dti-2192	159	7	to	to	ADP
dti-2192	159	8	poor	poor	ADJ
dti-2192	159	9	digestion	digestion	NOUN
dti-2192	159	10	and	and	CCONJ
dti-2192	159	11	absorption	absorption	NOUN
dti-2192	159	12	,	,	PUNCT
dti-2192	159	13	metabolic	metabolic	NOUN
dti-2192	159	14	changes	change	NOUN
dti-2192	159	15	in	in	ADP
dti-2192	159	16	the	the	DET
dti-2192	159	17	pancreas	pancrea	NOUN
dti-2192	159	18	,	,	PUNCT
dti-2192	159	19	such	such	ADJ
dti-2192	159	20	as	as	ADP
dti-2192	159	21	increased	increase	VERB
dti-2192	159	22	enzyme	enzyme	NOUN
dti-2192	159	23	secretion	secretion	NOUN
dti-2192	159	24	,	,	PUNCT
dti-2192	159	25	hypertrophy	hypertrophy	NOUN
dti-2192	159	26	and	and	CCONJ
dti-2192	159	27	hyperplasia	hyperplasia	NOUN
dti-2192	159	28	,	,	PUNCT
dti-2192	159	29	and	and	CCONJ
dti-2192	159	30	metabolic	metabolic	NOUN
dti-2192	159	31	disturbance	disturbance	NOUN
dti-2192	159	32	in	in	ADP
dti-2192	159	33	the	the	DET
dti-2192	159	34	use	use	NOUN
dti-2192	159	35	of	of	ADP
dti-2192	159	36	amino	amino	ADJ
dti-2192	159	37	acids	acid	NOUN
dti-2192	159	38	(	(	PUNCT
dti-2192	159	39	74	74	NUM
dti-2192	159	40	)	)	PUNCT
dti-2192	159	41	.	.	PUNCT
dti-2192	160	1	thus	thus	ADV
dti-2192	160	2	,	,	PUNCT
dti-2192	160	3	ptti	ptti	PROPN
dti-2192	160	4	was	be	AUX
dti-2192	160	5	evaluated	evaluate	VERB
dti-2192	160	6	for	for	ADP
dti-2192	160	7	possible	possible	ADJ
dti-2192	160	8	toxic	toxic	ADJ
dti-2192	160	9	effects	effect	NOUN
dti-2192	160	10	,	,	PUNCT
dti-2192	160	11	focusing	focus	VERB
dti-2192	160	12	on	on	ADP
dti-2192	160	13	the	the	DET
dti-2192	160	14	histopathological	histopathological	ADJ
dti-2192	160	15	and	and	CCONJ
dti-2192	160	16	stereological	stereological	ADJ
dti-2192	160	17	characteristics	characteristic	NOUN
dti-2192	160	18	of	of	ADP
dti-2192	160	19	organs	organ	NOUN
dti-2192	160	20	involved	involve	VERB
dti-2192	160	21	in	in	ADP
dti-2192	160	22	its	its	PRON
dti-2192	160	23	metabolism	metabolism	NOUN
dti-2192	160	24	,	,	PUNCT
dti-2192	160	25	processing	processing	NOUN
dti-2192	160	26	,	,	PUNCT
dti-2192	160	27	and	and	CCONJ
dti-2192	160	28	biological	biological	ADJ
dti-2192	160	29	activity	activity	NOUN
dti-2192	160	30	(	(	PUNCT
dti-2192	160	31	liver	liver	NOUN
dti-2192	160	32	and	and	CCONJ
dti-2192	160	33	pancreas	pancrea	NOUN
dti-2192	160	34	)	)	PUNCT
dti-2192	160	35	and	and	CCONJ
dti-2192	160	36	the	the	DET
dti-2192	160	37	tissues	tissue	NOUN
dti-2192	160	38	most	most	ADV
dti-2192	160	39	affected	affect	VERB
dti-2192	160	40	by	by	ADP
dti-2192	160	41	the	the	DET
dti-2192	160	42	obesity	obesity	NOUN
dti-2192	160	43	model	model	NOUN
dti-2192	160	44	(	(	PUNCT
dti-2192	160	45	small	small	ADJ
dti-2192	160	46	intestine	intestine	NOUN
dti-2192	160	47	and	and	CCONJ
dti-2192	160	48	visceral	visceral	ADJ
dti-2192	160	49	adipose	adipose	ADJ
dti-2192	160	50	tissue	tissue	NOUN
dti-2192	160	51	)	)	PUNCT
dti-2192	160	52	.	.	PUNCT
dti-2192	161	1	ptti	ptti	VERB
dti-2192	161	2	at	at	ADP
dti-2192	161	3	its	its	PRON
dti-2192	161	4	bioactive	bioactive	PROPN
dti-2192	161	5	dose	dose	NOUN
dti-2192	161	6	did	do	AUX
dti-2192	161	7	not	not	PART
dti-2192	161	8	cause	cause	VERB
dti-2192	161	9	signs	sign	NOUN
dti-2192	161	10	or	or	CCONJ
dti-2192	161	11	symptoms	symptom	NOUN
dti-2192	161	12	of	of	ADP
dti-2192	161	13	general	general	ADJ
dti-2192	161	14	toxicity	toxicity	NOUN
dti-2192	161	15	or	or	CCONJ
dti-2192	161	16	potential	potential	ADJ
dti-2192	161	17	damage	damage	NOUN
dti-2192	161	18	to	to	ADP
dti-2192	161	19	the	the	DET
dti-2192	161	20	liver	liver	NOUN
dti-2192	161	21	and	and	CCONJ
dti-2192	161	22	pancreatic	pancreatic	ADJ
dti-2192	161	23	tissue	tissue	NOUN
dti-2192	161	24	of	of	ADP
dti-2192	161	25	obese	obese	ADJ
dti-2192	161	26	wistar	wistar	PROPN
dti-2192	161	27	rats	rat	NOUN
dti-2192	161	28	.	.	PUNCT
dti-2192	162	1	ptti	ptti	PROPN
dti-2192	162	2	also	also	ADV
dti-2192	162	3	promoted	promote	VERB
dti-2192	162	4	a	a	DET
dti-2192	162	5	protective	protective	ADJ
dti-2192	162	6	effect	effect	NOUN
dti-2192	162	7	on	on	ADP
dti-2192	162	8	the	the	DET
dti-2192	162	9	intestines	intestine	NOUN
dti-2192	162	10	of	of	ADP
dti-2192	162	11	these	these	DET
dti-2192	162	12	animals	animal	NOUN
dti-2192	162	13	,	,	PUNCT
dti-2192	162	14	reducing	reduce	VERB
dti-2192	162	15	the	the	DET
dti-2192	162	16	loss	loss	NOUN
dti-2192	162	17	of	of	ADP
dti-2192	162	18	intestinal	intestinal	ADJ
dti-2192	162	19	villi	villi	NOUN
dti-2192	162	20	,	,	PUNCT
dti-2192	162	21	a	a	DET
dti-2192	162	22	well	well	ADV
dti-2192	162	23	-	-	PUNCT
dti-2192	162	24	characterized	characterize	VERB
dti-2192	162	25	damage	damage	NOUN
dti-2192	162	26	in	in	ADP
dti-2192	162	27	obesity	obesity	NOUN
dti-2192	162	28	models	model	NOUN
dti-2192	162	29	.	.	PUNCT
dti-2192	163	1	ptti	ptti	PROPN
dti-2192	163	2	reduced	reduce	VERB
dti-2192	163	3	the	the	DET
dti-2192	163	4	presence	presence	NOUN
dti-2192	163	5	of	of	ADP
dti-2192	163	6	inflammatory	inflammatory	ADJ
dti-2192	163	7	infiltrates	infiltrate	NOUN
dti-2192	163	8	in	in	ADP
dti-2192	163	9	perirenal	perirenal	ADJ
dti-2192	163	10	(	(	PUNCT
dti-2192	163	11	visceral	visceral	ADJ
dti-2192	163	12	)	)	PUNCT
dti-2192	163	13	adipose	adipose	NOUN
dti-2192	163	14	tissue	tissue	NOUN
dti-2192	163	15	.	.	PUNCT
dti-2192	164	1	therefore	therefore	ADV
dti-2192	164	2	,	,	PUNCT
dti-2192	164	3	its	its	PRON
dti-2192	164	4	use	use	NOUN
dti-2192	164	5	in	in	ADP
dti-2192	164	6	the	the	DET
dti-2192	164	7	tested	test	VERB
dti-2192	164	8	models	model	NOUN
dti-2192	164	9	is	be	AUX
dti-2192	164	10	safe	safe	ADJ
dti-2192	164	11	and	and	CCONJ
dti-2192	164	12	presents	present	VERB
dti-2192	164	13	anti	anti	ADJ
dti-2192	164	14	-	-	ADJ
dti-2192	164	15	inflammatory	inflammatory	ADJ
dti-2192	164	16	effects	effect	NOUN
dti-2192	164	17	(	(	PUNCT
dti-2192	164	18	unpublished	unpublished	ADJ
dti-2192	164	19	data	datum	NOUN
dti-2192	164	20	)	)	PUNCT
dti-2192	164	21	.	.	PUNCT
dti-2192	165	1	besides	besides	SCONJ
dti-2192	165	2	the	the	DET
dti-2192	165	3	effects	effect	NOUN
dti-2192	165	4	mentioned	mention	VERB
dti-2192	165	5	above	above	ADV
dti-2192	165	6	,	,	PUNCT
dti-2192	165	7	tti	tti	PROPN
dti-2192	165	8	is	be	AUX
dti-2192	165	9	a	a	DET
dti-2192	165	10	promising	promising	ADJ
dti-2192	165	11	molecule	molecule	NOUN
dti-2192	165	12	concerning	concern	VERB
dti-2192	165	13	the	the	DET
dti-2192	165	14	mechanisms	mechanism	NOUN
dti-2192	165	15	associated	associate	VERB
dti-2192	165	16	with	with	ADP
dti-2192	165	17	the	the	DET
dti-2192	165	18	inhibition	inhibition	NOUN
dti-2192	165	19	of	of	ADP
dti-2192	165	20	genes	gene	NOUN
dti-2192	165	21	involved	involve	VERB
dti-2192	165	22	in	in	ADP
dti-2192	165	23	the	the	DET
dti-2192	165	24	production	production	NOUN
dti-2192	165	25	of	of	ADP
dti-2192	165	26	ace-2	ace-2	ADJ
dti-2192	165	27	,	,	PUNCT
dti-2192	165	28	such	such	ADJ
dti-2192	165	29	as	as	ADP
dti-2192	165	30	tmprss2	tmprss2	ADV
dti-2192	165	31	and	and	CCONJ
dti-2192	165	32	furin	furin	NOUN
dti-2192	165	33	(	(	PUNCT
dti-2192	165	34	fig	fig	NOUN
dti-2192	165	35	.	.	PUNCT
dti-2192	165	36	1	1	NUM
dti-2192	165	37	)	)	PUNCT
dti-2192	165	38	.	.	PUNCT
dti-2192	166	1	these	these	DET
dti-2192	166	2	genes	gene	NOUN
dti-2192	166	3	probably	probably	ADV
dti-2192	166	4	act	act	VERB
dti-2192	166	5	by	by	ADP
dti-2192	166	6	fig	fig	NOUN
dti-2192	166	7	.	.	PUNCT
dti-2192	167	1	1	1	NUM
dti-2192	167	2	obesity	obesity	NOUN
dti-2192	167	3	and	and	CCONJ
dti-2192	167	4	associated	associated	ADJ
dti-2192	167	5	comorbidities	comorbiditie	NOUN
dti-2192	167	6	as	as	ADP
dti-2192	167	7	risk	risk	NOUN
dti-2192	167	8	factors	factor	NOUN
dti-2192	167	9	for	for	ADP
dti-2192	167	10	complications	complication	NOUN
dti-2192	167	11	from	from	ADP
dti-2192	167	12	sars	sar	NOUN
dti-2192	167	13	-	-	PUNCT
dti-2192	167	14	cov-2	cov-2	PART
dti-2192	167	15	infection	infection	NOUN
dti-2192	167	16	,	,	PUNCT
dti-2192	167	17	and	and	CCONJ
dti-2192	167	18	hypothesis	hypothesis	NOUN
dti-2192	167	19	of	of	ADP
dti-2192	167	20	the	the	DET
dti-2192	167	21	tti	tti	PROPN
dti-2192	167	22	mechanism	mechanism	NOUN
dti-2192	167	23	of	of	ADP
dti-2192	167	24	action	action	NOUN
dti-2192	167	25	.	.	PUNCT
dti-2192	168	1	obesity	obesity	NOUN
dti-2192	168	2	affects	affect	VERB
dti-2192	168	3	several	several	ADJ
dti-2192	168	4	organs	organ	NOUN
dti-2192	168	5	,	,	PUNCT
dti-2192	168	6	which	which	PRON
dti-2192	168	7	have	have	VERB
dti-2192	168	8	several	several	ADJ
dti-2192	168	9	responses	response	NOUN
dti-2192	168	10	,	,	PUNCT
dti-2192	168	11	such	such	ADJ
dti-2192	168	12	as	as	ADP
dti-2192	168	13	increased	increase	VERB
dti-2192	168	14	inflammation	inflammation	NOUN
dti-2192	168	15	,	,	PUNCT
dti-2192	168	16	changes	change	NOUN
dti-2192	168	17	in	in	ADP
dti-2192	168	18	sensitivity	sensitivity	NOUN
dti-2192	168	19	and	and	CCONJ
dti-2192	168	20	the	the	DET
dti-2192	168	21	action	action	NOUN
dti-2192	168	22	of	of	ADP
dti-2192	168	23	hormones	hormone	NOUN
dti-2192	168	24	,	,	PUNCT
dti-2192	168	25	dyslipidemia	dyslipidemia	NOUN
dti-2192	168	26	,	,	PUNCT
dti-2192	168	27	and	and	CCONJ
dti-2192	168	28	others	other	NOUN
dti-2192	168	29	.	.	PUNCT
dti-2192	169	1	this	this	DET
dti-2192	169	2	metabolic	metabolic	NOUN
dti-2192	169	3	deregulation	deregulation	NOUN
dti-2192	169	4	favors	favor	VERB
dti-2192	169	5	increased	increase	VERB
dti-2192	169	6	expression	expression	NOUN
dti-2192	169	7	of	of	ADP
dti-2192	169	8	ace-2	ace-2	NUM
dti-2192	169	9	,	,	PUNCT
dti-2192	169	10	which	which	PRON
dti-2192	169	11	is	be	AUX
dti-2192	169	12	cleaved	cleave	VERB
dti-2192	169	13	in	in	ADP
dti-2192	169	14	the	the	DET
dti-2192	169	15	cterminal	cterminal	ADJ
dti-2192	169	16	segment	segment	NOUN
dti-2192	169	17	by	by	ADP
dti-2192	169	18	proteases	protease	NOUN
dti-2192	169	19	such	such	ADJ
dti-2192	169	20	as	as	ADP
dti-2192	169	21	tmprss2	tmprss2	ADV
dti-2192	169	22	and	and	CCONJ
dti-2192	169	23	furin	furin	NOUN
dti-2192	169	24	,	,	PUNCT
dti-2192	169	25	and	and	CCONJ
dti-2192	169	26	there	there	PRON
dti-2192	169	27	is	be	VERB
dti-2192	169	28	activation	activation	NOUN
dti-2192	169	29	of	of	ADP
dti-2192	169	30	the	the	DET
dti-2192	169	31	spike	spike	ADJ
dti-2192	169	32	glycoprotein	glycoprotein	NOUN
dti-2192	169	33	,	,	PUNCT
dti-2192	169	34	so	so	SCONJ
dti-2192	169	35	this	this	DET
dti-2192	169	36	process	process	NOUN
dti-2192	169	37	facilitates	facilitate	VERB
dti-2192	169	38	the	the	DET
dti-2192	169	39	entry	entry	NOUN
dti-2192	169	40	of	of	ADP
dti-2192	169	41	sars	sar	NOUN
dti-2192	169	42	-	-	PUNCT
dti-2192	169	43	cov-2	cov-2	NOUN
dti-2192	169	44	into	into	ADP
dti-2192	169	45	the	the	DET
dti-2192	169	46	cells	cell	NOUN
dti-2192	169	47	,	,	PUNCT
dti-2192	169	48	causing	cause	VERB
dti-2192	169	49	viral	viral	ADJ
dti-2192	169	50	infection	infection	NOUN
dti-2192	169	51	.	.	PUNCT
dti-2192	170	1	also	also	ADV
dti-2192	170	2	,	,	PUNCT
dti-2192	170	3	3cl	3cl	ADJ
dti-2192	170	4	pro	pro	NOUN
dti-2192	170	5	is	be	AUX
dti-2192	170	6	considered	consider	VERB
dti-2192	170	7	a	a	DET
dti-2192	170	8	key	key	ADJ
dti-2192	170	9	component	component	NOUN
dti-2192	170	10	in	in	ADP
dti-2192	170	11	polyprotein	polyprotein	ADJ
dti-2192	170	12	processing	processing	NOUN
dti-2192	170	13	and	and	CCONJ
dti-2192	170	14	plays	play	VERB
dti-2192	170	15	an	an	DET
dti-2192	170	16	important	important	ADJ
dti-2192	170	17	role	role	NOUN
dti-2192	170	18	in	in	ADP
dti-2192	170	19	the	the	DET
dti-2192	170	20	replication	replication	NOUN
dti-2192	170	21	and	and	CCONJ
dti-2192	170	22	transcription	transcription	NOUN
dti-2192	170	23	of	of	ADP
dti-2192	170	24	viral	viral	ADJ
dti-2192	170	25	rna	rna	NOUN
dti-2192	170	26	.	.	PUNCT
dti-2192	171	1	the	the	DET
dti-2192	171	2	tti	tti	PROPN
dti-2192	171	3	effects	effect	NOUN
dti-2192	171	4	in	in	ADP
dti-2192	171	5	in	in	ADP
dti-2192	171	6	vitro	vitro	X
dti-2192	171	7	and	and	CCONJ
dti-2192	171	8	preclinical	preclinical	ADJ
dti-2192	171	9	studies	study	NOUN
dti-2192	171	10	show	show	VERB
dti-2192	171	11	several	several	ADJ
dti-2192	171	12	antiobesity	antiobesity	NOUN
dti-2192	171	13	and	and	CCONJ
dti-2192	171	14	anti	anti	ADJ
dti-2192	171	15	-	-	ADJ
dti-2192	171	16	inflammatory	inflammatory	ADJ
dti-2192	171	17	effects	effect	NOUN
dti-2192	171	18	and	and	CCONJ
dti-2192	171	19	appear	appear	VERB
dti-2192	171	20	to	to	PART
dti-2192	171	21	be	be	AUX
dti-2192	171	22	possible	possible	ADJ
dti-2192	171	23	inhibitors	inhibitor	NOUN
dti-2192	171	24	of	of	ADP
dti-2192	171	25	the	the	DET
dti-2192	171	26	proteases	protease	NOUN
dti-2192	171	27	tmprss2	tmprss2	VERB
dti-2192	171	28	,	,	PUNCT
dti-2192	171	29	furin	furin	NOUN
dti-2192	171	30	,	,	PUNCT
dti-2192	171	31	and	and	CCONJ
dti-2192	171	32	3clpro	3clpro	NUM
dti-2192	171	33	.	.	PUNCT
dti-2192	171	34	ace-2	ace-2	NUM
dti-2192	171	35	=	=	VERB
dti-2192	171	36	angiotensin	angiotensin	NOUN
dti-2192	171	37	-	-	PUNCT
dti-2192	171	38	converting	convert	VERB
dti-2192	171	39	enzyme	enzyme	NOUN
dti-2192	171	40	2	2	NUM
dti-2192	171	41	;	;	PUNCT
dti-2192	171	42	cck	cck	ADJ
dti-2192	171	43	=	=	SYM
dti-2192	171	44	cholecystokinin	cholecystokinin	NOUN
dti-2192	171	45	;	;	PUNCT
dti-2192	171	46	furin	furin	NOUN
dti-2192	171	47	=	=	SYM
dti-2192	171	48	member	member	NOUN
dti-2192	171	49	of	of	ADP
dti-2192	171	50	the	the	DET
dti-2192	171	51	mammalian	mammalian	ADJ
dti-2192	171	52	prohormone	prohormone	NOUN
dti-2192	171	53	-	-	PUNCT
dti-2192	171	54	protein	protein	NOUN
dti-2192	171	55	convertases	convertase	NOUN
dti-2192	171	56	family	family	NOUN
dti-2192	171	57	;	;	PUNCT
dti-2192	171	58	hne	hne	PROPN
dti-2192	171	59	=	=	PROPN
dti-2192	171	60	human	human	ADJ
dti-2192	171	61	neutrophil	neutrophil	ADJ
dti-2192	171	62	elastase	elastase	NOUN
dti-2192	171	63	;	;	PUNCT
dti-2192	171	64	il-1β	il-1β	PROPN
dti-2192	171	65	=	=	SYM
dti-2192	171	66	interleukin	interleukin	NOUN
dti-2192	171	67	1	1	NUM
dti-2192	171	68	-	-	SYM
dti-2192	171	69	β	β	NOUN
dti-2192	171	70	;	;	PUNCT
dti-2192	171	71	lps	lps	PROPN
dti-2192	171	72	=	=	PUNCT
dti-2192	171	73	lipopolysaccharide	lipopolysaccharide	ADJ
dti-2192	171	74	;	;	PUNCT
dti-2192	171	75	mcp-1	mcp-1	NOUN
dti-2192	171	76	=	=	NUM
dti-2192	171	77	monocyte	monocyte	NOUN
dti-2192	171	78	chemoattractant	chemoattractant	NOUN
dti-2192	171	79	protein	protein	NOUN
dti-2192	171	80	1	1	NUM
dti-2192	171	81	;	;	PUNCT
dti-2192	171	82	srebp	srebp	ADJ
dti-2192	171	83	=	=	SYM
dti-2192	171	84	sterol	sterol	NOUN
dti-2192	171	85	regulatory	regulatory	ADJ
dti-2192	171	86	elementbinding	elementbinde	VERB
dti-2192	171	87	proteins	protein	NOUN
dti-2192	171	88	;	;	PUNCT
dti-2192	171	89	tg	tg	PROPN
dti-2192	171	90	=	=	PUNCT
dti-2192	171	91	triglyceride	triglyceride	ADJ
dti-2192	171	92	;	;	PUNCT
dti-2192	171	93	tmprss2	tmprss2	ADP
dti-2192	171	94	=	=	SYM
dti-2192	171	95	transmembrane	transmembrane	ADJ
dti-2192	171	96	serine	serine	NOUN
dti-2192	171	97	protease	protease	NOUN
dti-2192	171	98	2	2	NUM
dti-2192	171	99	;	;	PUNCT
dti-2192	171	100	tnf	tnf	PROPN
dti-2192	171	101	-	-	PUNCT
dti-2192	171	102	α	α	PROPN
dti-2192	171	103	=	=	PUNCT
dti-2192	171	104	tumor	tumor	NOUN
dti-2192	171	105	necrosis	necrosis	NOUN
dti-2192	171	106	factor	factor	NOUN
dti-2192	171	107	α	α	NOUN
dti-2192	171	108	;	;	PUNCT
dti-2192	171	109	tti	tti	PROPN
dti-2192	171	110	=	=	PUNCT
dti-2192	171	111	trypsin	trypsin	NOUN
dti-2192	171	112	inhibitor	inhibitor	NOUN
dti-2192	171	113	from	from	ADP
dti-2192	171	114	tamarind	tamarind	NOUN
dti-2192	171	115	;	;	PUNCT
dti-2192	171	116	vldl	vldl	NOUN
dti-2192	171	117	-	-	PUNCT
dti-2192	171	118	c	c	NOUN
dti-2192	171	119	=	=	PUNCT
dti-2192	171	120	very	very	ADV
dti-2192	171	121	-	-	PUNCT
dti-2192	171	122	low	low	ADJ
dti-2192	171	123	-	-	PUNCT
dti-2192	171	124	density	density	NOUN
dti-2192	171	125	lipoprotein	lipoprotein	ADJ
dti-2192	171	126	cholesterol	cholesterol	NOUN
dti-2192	171	127	;	;	PUNCT
dti-2192	171	128	3cl	3cl	ADJ
dti-2192	171	129	pro	pro	X
dti-2192	171	130	=	=	ADJ
dti-2192	171	131	3c	3c	NUM
dti-2192	171	132	-	-	PUNCT
dti-2192	171	133	like	like	ADJ
dti-2192	171	134	protease	protease	NOUN
dti-2192	171	135	.	.	PUNCT
dti-2192	172	1	protein	protein	NOUN
dti-2192	172	2	with	with	ADP
dti-2192	172	3	potential	potential	NOUN
dti-2192	172	4	for	for	ADP
dti-2192	172	5	combating	combat	VERB
dti-2192	172	6	sars	sar	NOUN
dti-2192	172	7	-	-	PUNCT
dti-2192	172	8	cov-2	cov-2	NOUN
dti-2192	172	9	infection	infection	NOUN
dti-2192	172	10	in	in	ADP
dti-2192	172	11	obesity10	obesity10	NOUN
dti-2192	172	12	©	©	PROPN
dti-2192	172	13	2021	2021	NUM
dti-2192	172	14	the	the	DET
dti-2192	172	15	authors	author	NOUN
dti-2192	172	16	.	.	PUNCT
dti-2192	173	1	drug	drug	NOUN
dti-2192	173	2	target	target	NOUN
dti-2192	173	3	insights	insight	NOUN
dti-2192	173	4	issn	issn	VERB
dti-2192	173	5	1177	1177	NUM
dti-2192	173	6	-	-	SYM
dti-2192	173	7	3928	3928	NUM
dti-2192	173	8	www.aboutscience.eu/dti	www.aboutscience.eu/dti	NOUN
dti-2192	173	9	changing	change	VERB
dti-2192	173	10	the	the	DET
dti-2192	173	11	organism	organism	NOUN
dti-2192	173	12	’s	’s	PART
dti-2192	173	13	epigenetic	epigenetic	ADJ
dti-2192	173	14	system	system	NOUN
dti-2192	173	15	responsible	responsible	ADJ
dti-2192	173	16	for	for	ADP
dti-2192	173	17	the	the	DET
dti-2192	173	18	increase	increase	NOUN
dti-2192	173	19	in	in	ADP
dti-2192	173	20	ace-2	ace-2	PUNCT
dti-2192	173	21	expression	expression	NOUN
dti-2192	173	22	,	,	PUNCT
dti-2192	173	23	a	a	DET
dti-2192	173	24	potential	potential	ADJ
dti-2192	173	25	target	target	NOUN
dti-2192	173	26	for	for	ADP
dti-2192	173	27	antiviral	antiviral	ADJ
dti-2192	173	28	intervention	intervention	NOUN
dti-2192	173	29	by	by	ADP
dti-2192	173	30	sars	sar	NOUN
dti-2192	173	31	-	-	PUNCT
dti-2192	173	32	cov-2	cov-2	NOUN
dti-2192	173	33	.	.	PUNCT
dti-2192	174	1	adipokines	adipokine	NOUN
dti-2192	174	2	secreted	secrete	VERB
dti-2192	174	3	by	by	ADP
dti-2192	174	4	adipose	adipose	ADJ
dti-2192	174	5	tissue	tissue	NOUN
dti-2192	174	6	can	can	AUX
dti-2192	174	7	also	also	ADV
dti-2192	174	8	affect	affect	VERB
dti-2192	174	9	airway	airway	NOUN
dti-2192	174	10	function	function	NOUN
dti-2192	174	11	.	.	PUNCT
dti-2192	175	1	leptin	leptin	NOUN
dti-2192	175	2	is	be	AUX
dti-2192	175	3	involved	involve	VERB
dti-2192	175	4	in	in	ADP
dti-2192	175	5	neonatal	neonatal	ADJ
dti-2192	175	6	lung	lung	NOUN
dti-2192	175	7	development	development	NOUN
dti-2192	175	8	,	,	PUNCT
dti-2192	175	9	surfactant	surfactant	ADJ
dti-2192	175	10	production	production	NOUN
dti-2192	175	11	(	(	PUNCT
dti-2192	175	12	75,76	75,76	NUM
dti-2192	175	13	)	)	PUNCT
dti-2192	175	14	,	,	PUNCT
dti-2192	175	15	and	and	CCONJ
dti-2192	175	16	regulation	regulation	NOUN
dti-2192	175	17	of	of	ADP
dti-2192	175	18	ventilatory	ventilatory	ADJ
dti-2192	175	19	impulse	impulse	ADJ
dti-2192	175	20	(	(	PUNCT
dti-2192	175	21	76,77	76,77	NUM
dti-2192	175	22	)	)	PUNCT
dti-2192	175	23	.	.	PUNCT
dti-2192	176	1	studies	study	NOUN
dti-2192	176	2	have	have	AUX
dti-2192	176	3	consistently	consistently	ADV
dti-2192	176	4	demonstrated	demonstrate	VERB
dti-2192	176	5	the	the	DET
dti-2192	176	6	association	association	NOUN
dti-2192	176	7	of	of	ADP
dti-2192	176	8	high	high	ADJ
dti-2192	176	9	concentrations	concentration	NOUN
dti-2192	176	10	of	of	ADP
dti-2192	176	11	leptin	leptin	NOUN
dti-2192	176	12	and	and	CCONJ
dti-2192	176	13	asthma	asthma	NOUN
dti-2192	176	14	(	(	PUNCT
dti-2192	176	15	78,79	78,79	NOUN
dti-2192	176	16	)	)	PUNCT
dti-2192	176	17	.	.	PUNCT
dti-2192	177	1	the	the	DET
dti-2192	177	2	leptin	leptin	NOUN
dti-2192	177	3	concentration	concentration	NOUN
dti-2192	177	4	was	be	AUX
dti-2192	177	5	reduced	reduce	VERB
dti-2192	177	6	with	with	ADP
dti-2192	177	7	the	the	DET
dti-2192	177	8	use	use	NOUN
dti-2192	177	9	of	of	ADP
dti-2192	177	10	tti	tti	PROPN
dti-2192	177	11	in	in	ADP
dti-2192	177	12	animal	animal	NOUN
dti-2192	177	13	models	model	NOUN
dti-2192	177	14	(	(	PUNCT
dti-2192	177	15	63,70	63,70	NOUN
dti-2192	177	16	)	)	PUNCT
dti-2192	177	17	.	.	PUNCT
dti-2192	178	1	several	several	ADJ
dti-2192	178	2	studies	study	NOUN
dti-2192	178	3	with	with	ADP
dti-2192	178	4	trypsin	trypsin	NOUN
dti-2192	178	5	inhibitors	inhibitor	NOUN
dti-2192	178	6	were	be	AUX
dti-2192	178	7	related	relate	VERB
dti-2192	178	8	to	to	ADP
dti-2192	178	9	obesity	obesity	NOUN
dti-2192	178	10	and	and	CCONJ
dti-2192	178	11	its	its	PRON
dti-2192	178	12	complications	complication	NOUN
dti-2192	178	13	(	(	PUNCT
dti-2192	178	14	59	59	NUM
dti-2192	178	15	)	)	PUNCT
dti-2192	178	16	.	.	PUNCT
dti-2192	179	1	according	accord	VERB
dti-2192	179	2	to	to	ADP
dti-2192	179	3	fook	fook	PROPN
dti-2192	179	4	et	et	PROPN
dti-2192	179	5	al	al	PROPN
dti-2192	179	6	.	.	PROPN
dti-2192	180	1	(	(	PUNCT
dti-2192	180	2	80	80	NUM
dti-2192	180	3	)	)	PUNCT
dti-2192	180	4	,	,	PUNCT
dti-2192	180	5	tti	tti	PROPN
dti-2192	180	6	showed	show	VERB
dti-2192	180	7	selective	selective	ADJ
dti-2192	180	8	activity	activity	NOUN
dti-2192	180	9	,	,	PUNCT
dti-2192	180	10	being	be	AUX
dti-2192	180	11	highly	highly	ADV
dti-2192	180	12	effective	effective	ADJ
dti-2192	180	13	against	against	ADP
dti-2192	180	14	serine	serine	NOUN
dti-2192	180	15	proteinases	proteinase	NOUN
dti-2192	180	16	,	,	PUNCT
dti-2192	180	17	especially	especially	ADV
dti-2192	180	18	against	against	ADP
dti-2192	180	19	bovine	bovine	NOUN
dti-2192	180	20	trypsin	trypsin	NOUN
dti-2192	180	21	and	and	CCONJ
dti-2192	180	22	neutrophil	neutrophil	ADJ
dti-2192	180	23	elastase	elastase	NOUN
dti-2192	180	24	isolated	isolate	VERB
dti-2192	180	25	from	from	ADP
dti-2192	180	26	humans	human	NOUN
dti-2192	180	27	.	.	PUNCT
dti-2192	181	1	the	the	DET
dti-2192	181	2	ic50	ic50	PROPN
dti-2192	181	3	value	value	NOUN
dti-2192	181	4	was	be	AUX
dti-2192	181	5	determined	determine	VERB
dti-2192	181	6	to	to	PART
dti-2192	181	7	be	be	AUX
dti-2192	181	8	55.96	55.96	NUM
dti-2192	181	9	μg	μg	NOUN
dti-2192	181	10	/	/	SYM
dti-2192	181	11	ml	ml	PROPN
dti-2192	181	12	.	.	PUNCT
dti-2192	182	1	the	the	DET
dti-2192	182	2	inhibitor	inhibitor	NOUN
dti-2192	182	3	also	also	ADV
dti-2192	182	4	showed	show	VERB
dti-2192	182	5	no	no	DET
dti-2192	182	6	cytotoxic	cytotoxic	ADJ
dti-2192	182	7	or	or	CCONJ
dti-2192	182	8	hemolytic	hemolytic	ADJ
dti-2192	182	9	activity	activity	NOUN
dti-2192	182	10	in	in	ADP
dti-2192	182	11	human	human	ADJ
dti-2192	182	12	blood	blood	NOUN
dti-2192	182	13	cells	cell	NOUN
dti-2192	182	14	.	.	PUNCT
dti-2192	183	1	in	in	ADP
dti-2192	183	2	addition	addition	NOUN
dti-2192	183	3	,	,	PUNCT
dti-2192	183	4	it	it	PRON
dti-2192	183	5	exhibited	exhibit	VERB
dti-2192	183	6	different	different	ADJ
dti-2192	183	7	inhibition	inhibition	NOUN
dti-2192	183	8	of	of	ADP
dti-2192	183	9	the	the	DET
dti-2192	183	10	release	release	NOUN
dti-2192	183	11	of	of	ADP
dti-2192	183	12	elastase	elastase	NOUN
dti-2192	183	13	by	by	ADP
dti-2192	183	14	platelet	platelet	NOUN
dti-2192	183	15	-	-	PUNCT
dti-2192	183	16	activating	activate	VERB
dti-2192	183	17	factor	factor	NOUN
dti-2192	183	18	(	(	PUNCT
dti-2192	183	19	paf	paf	NOUN
dti-2192	183	20	;	;	PUNCT
dti-2192	183	21	44.6	44.6	NUM
dti-2192	183	22	%	%	NOUN
dti-2192	183	23	)	)	PUNCT
dti-2192	183	24	and	and	CCONJ
dti-2192	183	25	release	release	NOUN
dti-2192	183	26	by	by	ADP
dti-2192	183	27	n	n	CCONJ
dti-2192	183	28	-	-	PUNCT
dti-2192	183	29	formyl	formyl	NOUN
dti-2192	183	30	-	-	PUNCT
dti-2192	183	31	l	l	NOUN
dti-2192	183	32	-	-	PUNCT
dti-2192	183	33	methionyl	methionyl	NOUN
dti-2192	183	34	-	-	PUNCT
dti-2192	183	35	l	l	NOUN
dti-2192	183	36	-	-	PUNCT
dti-2192	183	37	leucyl	leucyl	NOUN
dti-2192	183	38	-	-	PUNCT
dti-2192	183	39	phenylalanine	phenylalanine	NOUN
dti-2192	183	40	(	(	PUNCT
dti-2192	183	41	fmlp	fmlp	INTJ
dti-2192	183	42	;	;	PUNCT
dti-2192	183	43	28.4	28.4	NUM
dti-2192	183	44	%	%	NOUN
dti-2192	183	45	)	)	PUNCT
dti-2192	183	46	,	,	PUNCT
dti-2192	183	47	preferentially	preferentially	ADV
dti-2192	183	48	affecting	affect	VERB
dti-2192	183	49	elastase	elastase	NOUN
dti-2192	183	50	release	release	NOUN
dti-2192	183	51	by	by	ADP
dti-2192	183	52	paf	paf	PROPN
dti-2192	183	53	stimuli	stimulus	NOUN
dti-2192	183	54	.	.	PUNCT
dti-2192	184	1	this	this	PRON
dti-2192	184	2	may	may	AUX
dti-2192	184	3	indicate	indicate	VERB
dti-2192	184	4	selective	selective	ADJ
dti-2192	184	5	inhibition	inhibition	NOUN
dti-2192	184	6	in	in	ADP
dti-2192	184	7	the	the	DET
dti-2192	184	8	receptors	receptor	NOUN
dti-2192	184	9	of	of	ADP
dti-2192	184	10	the	the	DET
dti-2192	184	11	paf	paf	NOUN
dti-2192	184	12	(	(	PUNCT
dti-2192	184	13	80	80	NUM
dti-2192	184	14	)	)	PUNCT
dti-2192	184	15	.	.	PUNCT
dti-2192	185	1	the	the	DET
dti-2192	185	2	same	same	ADJ
dti-2192	185	3	research	research	NOUN
dti-2192	185	4	group	group	NOUN
dti-2192	185	5	in	in	ADP
dti-2192	185	6	2010	2010	NUM
dti-2192	185	7	conducted	conduct	VERB
dti-2192	185	8	another	another	DET
dti-2192	185	9	study	study	NOUN
dti-2192	185	10	and	and	CCONJ
dti-2192	185	11	demonstrated	demonstrate	VERB
dti-2192	185	12	that	that	SCONJ
dti-2192	185	13	the	the	DET
dti-2192	185	14	soy	soy	NOUN
dti-2192	185	15	inhibitor	inhibitor	NOUN
dti-2192	185	16	(	(	PUNCT
dti-2192	185	17	skti	skti	PROPN
dti-2192	185	18	)	)	PUNCT
dti-2192	185	19	reduced	reduce	VERB
dti-2192	185	20	lipopolysaccharide	lipopolysaccharide	ADV
dti-2192	185	21	(	(	PUNCT
dti-2192	185	22	lps)-induced	lps)-induce	VERB
dti-2192	185	23	acute	acute	ADJ
dti-2192	185	24	lung	lung	NOUN
dti-2192	185	25	injury	injury	NOUN
dti-2192	185	26	in	in	ADP
dti-2192	185	27	a	a	DET
dti-2192	185	28	preclinical	preclinical	ADJ
dti-2192	185	29	model	model	NOUN
dti-2192	185	30	,	,	PUNCT
dti-2192	185	31	significantly	significantly	ADV
dti-2192	185	32	suppressing	suppress	VERB
dti-2192	185	33	the	the	DET
dti-2192	185	34	inflammatory	inflammatory	ADJ
dti-2192	185	35	effects	effect	NOUN
dti-2192	185	36	caused	cause	VERB
dti-2192	185	37	by	by	ADP
dti-2192	185	38	elastase	elastase	NOUN
dti-2192	185	39	in	in	ADP
dti-2192	185	40	a	a	DET
dti-2192	185	41	dose	dose	NOUN
dti-2192	185	42	-	-	PUNCT
dti-2192	185	43	dependent	dependent	ADJ
dti-2192	185	44	manner	manner	NOUN
dti-2192	185	45	,	,	PUNCT
dti-2192	185	46	suggesting	suggest	VERB
dti-2192	185	47	the	the	DET
dti-2192	185	48	route	route	NOUN
dti-2192	185	49	of	of	ADP
dti-2192	185	50	inhibition	inhibition	NOUN
dti-2192	185	51	of	of	ADP
dti-2192	185	52	human	human	ADJ
dti-2192	185	53	neutrophil	neutrophil	ADJ
dti-2192	185	54	elastase	elastase	NOUN
dti-2192	185	55	as	as	ADP
dti-2192	185	56	a	a	DET
dti-2192	185	57	promoter	promoter	NOUN
dti-2192	185	58	of	of	ADP
dti-2192	185	59	the	the	DET
dti-2192	185	60	improvement	improvement	NOUN
dti-2192	185	61	(	(	PUNCT
dti-2192	185	62	81	81	NUM
dti-2192	185	63	)	)	PUNCT
dti-2192	185	64	.	.	PUNCT
dti-2192	186	1	several	several	ADJ
dti-2192	186	2	computational	computational	ADJ
dti-2192	186	3	molecular	molecular	ADJ
dti-2192	186	4	docking	docking	NOUN
dti-2192	186	5	studies	study	NOUN
dti-2192	186	6	have	have	AUX
dti-2192	186	7	been	be	AUX
dti-2192	186	8	carried	carry	VERB
dti-2192	186	9	out	out	ADP
dti-2192	186	10	with	with	ADP
dti-2192	186	11	some	some	DET
dti-2192	186	12	compounds	compound	NOUN
dti-2192	186	13	to	to	PART
dti-2192	186	14	model	model	VERB
dti-2192	186	15	binding	bind	VERB
dti-2192	186	16	interactions	interaction	NOUN
dti-2192	186	17	of	of	ADP
dti-2192	186	18	various	various	ADJ
dti-2192	186	19	3cl	3cl	ADJ
dti-2192	186	20	pro	pro	ADJ
dti-2192	186	21	inhibitors	inhibitor	NOUN
dti-2192	186	22	and	and	CCONJ
dti-2192	186	23	other	other	ADJ
dti-2192	186	24	proteases	protease	NOUN
dti-2192	186	25	,	,	PUNCT
dti-2192	186	26	such	such	ADJ
dti-2192	186	27	as	as	ADP
dti-2192	186	28	tmprss2	tmprss2	ADV
dti-2192	186	29	(	(	PUNCT
dti-2192	186	30	37,82	37,82	NUM
dti-2192	186	31	-	-	SYM
dti-2192	186	32	84	84	NUM
dti-2192	186	33	)	)	PUNCT
dti-2192	186	34	.	.	PUNCT
dti-2192	187	1	ptti	ptti	ADJ
dti-2192	187	2	-	-	PUNCT
dti-2192	187	3	derived	derive	VERB
dti-2192	187	4	peptides	peptide	NOUN
dti-2192	187	5	are	be	AUX
dti-2192	187	6	also	also	ADV
dti-2192	187	7	shown	show	VERB
dti-2192	187	8	to	to	PART
dti-2192	187	9	be	be	AUX
dti-2192	187	10	strong	strong	ADJ
dti-2192	187	11	candidates	candidate	NOUN
dti-2192	187	12	for	for	ADP
dti-2192	187	13	blocking	block	VERB
dti-2192	187	14	these	these	DET
dti-2192	187	15	proteases	protease	NOUN
dti-2192	187	16	since	since	SCONJ
dti-2192	187	17	tti	tti	PROPN
dti-2192	187	18	is	be	AUX
dti-2192	187	19	known	know	VERB
dti-2192	187	20	to	to	PART
dti-2192	187	21	inhibit	inhibit	VERB
dti-2192	187	22	serine	serine	NOUN
dti-2192	187	23	proteases	protease	NOUN
dti-2192	187	24	such	such	ADJ
dti-2192	187	25	as	as	ADP
dti-2192	187	26	trypsin	trypsin	NOUN
dti-2192	187	27	and	and	CCONJ
dti-2192	187	28	chymotrypsin	chymotrypsin	NOUN
dti-2192	187	29	,	,	PUNCT
dti-2192	187	30	as	as	SCONJ
dti-2192	187	31	previously	previously	ADV
dti-2192	187	32	demonstrated	demonstrate	VERB
dti-2192	187	33	.	.	PUNCT
dti-2192	188	1	conclusions	conclusion	NOUN
dti-2192	188	2	therefore	therefore	ADV
dti-2192	188	3	,	,	PUNCT
dti-2192	188	4	trypsin	trypsin	NOUN
dti-2192	188	5	inhibitors	inhibitor	NOUN
dti-2192	188	6	are	be	AUX
dti-2192	188	7	promising	promise	VERB
dti-2192	188	8	alternatives	alternative	NOUN
dti-2192	188	9	,	,	PUNCT
dti-2192	188	10	in	in	ADP
dti-2192	188	11	addition	addition	NOUN
dti-2192	188	12	to	to	ADP
dti-2192	188	13	others	other	NOUN
dti-2192	188	14	already	already	ADV
dti-2192	188	15	discussed	discuss	VERB
dti-2192	188	16	in	in	ADP
dti-2192	188	17	the	the	DET
dti-2192	188	18	scientific	scientific	ADJ
dti-2192	188	19	community	community	NOUN
dti-2192	188	20	,	,	PUNCT
dti-2192	188	21	which	which	PRON
dti-2192	188	22	can	can	AUX
dti-2192	188	23	be	be	AUX
dti-2192	188	24	used	use	VERB
dti-2192	188	25	as	as	ADP
dti-2192	188	26	adjuvants	adjuvant	NOUN
dti-2192	188	27	in	in	ADP
dti-2192	188	28	covid-19	covid-19	PROPN
dti-2192	188	29	,	,	PUNCT
dti-2192	188	30	especially	especially	ADV
dti-2192	188	31	in	in	ADP
dti-2192	188	32	obese	obese	ADJ
dti-2192	188	33	patients	patient	NOUN
dti-2192	188	34	.	.	PUNCT
dti-2192	189	1	thus	thus	ADV
dti-2192	189	2	,	,	PUNCT
dti-2192	189	3	the	the	DET
dti-2192	189	4	tamarind	tamarind	NOUN
dti-2192	189	5	seed	seed	NOUN
dti-2192	189	6	trypsin	trypsin	NOUN
dti-2192	189	7	inhibitor	inhibitor	NOUN
dti-2192	189	8	may	may	AUX
dti-2192	189	9	also	also	ADV
dti-2192	189	10	be	be	AUX
dti-2192	189	11	a	a	DET
dti-2192	189	12	preventive	preventive	ADJ
dti-2192	189	13	or	or	CCONJ
dti-2192	189	14	adjuvant	adjuvant	ADJ
dti-2192	189	15	drug	drug	NOUN
dti-2192	189	16	in	in	ADP
dti-2192	189	17	the	the	DET
dti-2192	189	18	context	context	NOUN
dti-2192	189	19	of	of	ADP
dti-2192	189	20	covid-19	covid-19	PROPN
dti-2192	189	21	,	,	PUNCT
dti-2192	189	22	especially	especially	ADV
dti-2192	189	23	in	in	ADP
dti-2192	189	24	worsened	worsen	VERB
dti-2192	189	25	inflammatory	inflammatory	ADJ
dti-2192	189	26	conditions	condition	NOUN
dti-2192	189	27	,	,	PUNCT
dti-2192	189	28	such	such	ADJ
dti-2192	189	29	as	as	ADP
dti-2192	189	30	obesity	obesity	NOUN
dti-2192	189	31	.	.	PUNCT
dti-2192	190	1	funding	fund	VERB
dti-2192	190	2	this	this	DET
dti-2192	190	3	study	study	NOUN
dti-2192	190	4	was	be	AUX
dti-2192	190	5	financed	finance	VERB
dti-2192	190	6	in	in	ADP
dti-2192	190	7	part	part	NOUN
dti-2192	190	8	by	by	ADP
dti-2192	190	9	the	the	DET
dti-2192	190	10	coordenação	coordenação	PROPN
dti-2192	190	11	de	de	PROPN
dti-2192	190	12	aperfeiçoamento	aperfeiçoamento	PROPN
dti-2192	190	13	de	de	X
dti-2192	190	14	pessoal	pessoal	PROPN
dti-2192	190	15	de	de	PROPN
dti-2192	190	16	nível	nível	PROPN
dti-2192	190	17	superior	superior	PROPN
dti-2192	190	18	—	—	PUNCT
dti-2192	190	19	brasil	brasil	PROPN
dti-2192	190	20	(	(	PUNCT
dti-2192	190	21	capes	cape	NOUN
dti-2192	190	22	)	)	PUNCT
dti-2192	190	23	,	,	PUNCT
dti-2192	190	24	finance	finance	NOUN
dti-2192	190	25	code	code	NOUN
dti-2192	190	26	001	001	NUM
dti-2192	190	27	.	.	PUNCT
dti-2192	191	1	acknowledgments	acknowledgment	NOUN
dti-2192	191	2	the	the	DET
dti-2192	191	3	authors	author	NOUN
dti-2192	191	4	thank	thank	VERB
dti-2192	191	5	professor	professor	PROPN
dti-2192	191	6	dr	dr	PROPN
dti-2192	191	7	.	.	PROPN
dti-2192	191	8	elizeu	elizeu	PROPN
dti-2192	191	9	antunes	antunes	PROPN
dti-2192	191	10	dos	do	NOUN
dti-2192	191	11	santos	santo	NOUN
dti-2192	191	12	for	for	ADP
dti-2192	191	13	figure	figure	NOUN
dti-2192	191	14	editing	editing	NOUN
dti-2192	191	15	and	and	CCONJ
dti-2192	191	16	the	the	DET
dti-2192	191	17	federal	federal	ADJ
dti-2192	191	18	university	university	PROPN
dti-2192	191	19	of	of	ADP
dti-2192	191	20	rio	rio	PROPN
dti-2192	191	21	grande	grande	PROPN
dti-2192	191	22	do	do	VERB
dti-2192	191	23	norte	norte	NOUN
dti-2192	191	24	(	(	PUNCT
dti-2192	191	25	ufrn	ufrn	PROPN
dti-2192	191	26	)	)	PUNCT
dti-2192	191	27	,	,	PUNCT
dti-2192	191	28	especially	especially	ADV
dti-2192	191	29	the	the	DET
dti-2192	191	30	pro	pro	ADJ
dti-2192	191	31	-	-	ADJ
dti-2192	191	32	rectory	rectory	ADJ
dti-2192	191	33	of	of	ADP
dti-2192	191	34	postgraduate	postgraduate	NOUN
dti-2192	191	35	and	and	CCONJ
dti-2192	191	36	the	the	DET
dti-2192	191	37	pro	pro	ADJ
dti-2192	191	38	-	-	ADJ
dti-2192	191	39	rectory	rectory	ADJ
dti-2192	191	40	of	of	ADP
dti-2192	191	41	research	research	NOUN
dti-2192	191	42	,	,	PUNCT
dti-2192	191	43	for	for	ADP
dti-2192	191	44	all	all	DET
dti-2192	191	45	efforts	effort	NOUN
dti-2192	191	46	dedicated	dedicate	VERB
dti-2192	191	47	to	to	ADP
dti-2192	191	48	supporting	support	VERB
dti-2192	191	49	the	the	DET
dti-2192	191	50	research	research	NOUN
dti-2192	191	51	in	in	ADP
dti-2192	191	52	our	our	PRON
dti-2192	191	53	institution	institution	NOUN
dti-2192	191	54	.	.	PUNCT
dti-2192	192	1	disclosures	disclosure	VERB
dti-2192	192	2	conflict	conflict	NOUN
dti-2192	192	3	of	of	ADP
dti-2192	192	4	interest	interest	NOUN
dti-2192	192	5	:	:	PUNCT
dti-2192	192	6	the	the	DET
dti-2192	192	7	authors	author	NOUN
dti-2192	192	8	declare	declare	VERB
dti-2192	192	9	no	no	DET
dti-2192	192	10	conflicts	conflict	NOUN
dti-2192	192	11	of	of	ADP
dti-2192	192	12	interest	interest	NOUN
dti-2192	192	13	.	.	PUNCT
dti-2192	193	1	financial	financial	ADJ
dti-2192	193	2	support	support	NOUN
dti-2192	193	3	:	:	PUNCT
dti-2192	193	4	this	this	DET
dti-2192	193	5	study	study	NOUN
dti-2192	193	6	was	be	AUX
dti-2192	193	7	financed	finance	VERB
dti-2192	193	8	in	in	ADP
dti-2192	193	9	part	part	NOUN
dti-2192	193	10	by	by	ADP
dti-2192	193	11	the	the	DET
dti-2192	193	12	coordenação	coordenação	PROPN
dti-2192	193	13	de	de	PROPN
dti-2192	193	14	aperfeiçoamento	aperfeiçoamento	PROPN
dti-2192	193	15	de	de	X
dti-2192	193	16	pessoal	pessoal	PROPN
dti-2192	193	17	de	de	PROPN
dti-2192	193	18	nível	nível	PROPN
dti-2192	193	19	superior	superior	PROPN
dti-2192	193	20	—	—	PUNCT
dti-2192	193	21	brasil	brasil	PROPN
dti-2192	193	22	(	(	PUNCT
dti-2192	193	23	capes	cape	NOUN
dti-2192	193	24	)	)	PUNCT
dti-2192	193	25	,	,	PUNCT
dti-2192	193	26	finance	finance	NOUN
dti-2192	193	27	code	code	NOUN
dti-2192	193	28	001	001	NUM
dti-2192	193	29	.	.	PUNCT
dti-2192	194	1	references	reference	NOUN
dti-2192	194	2	1	1	NUM
dti-2192	194	3	.	.	PUNCT
dti-2192	195	1	dietz	dietz	PROPN
dti-2192	195	2	w	w	PROPN
dti-2192	195	3	,	,	PUNCT
dti-2192	195	4	santos	santos	PROPN
dti-2192	195	5	-	-	PUNCT
dti-2192	195	6	burgoa	burgoa	PROPN
dti-2192	195	7	c.	c.	PROPN
dti-2192	195	8	obesity	obesity	PROPN
dti-2192	195	9	and	and	CCONJ
dti-2192	195	10	its	its	PRON
dti-2192	195	11	implications	implication	NOUN
dti-2192	195	12	for	for	ADP
dti-2192	195	13	covid-19	covid-19	PROPN
dti-2192	195	14	mortality	mortality	NOUN
dti-2192	195	15	.	.	PUNCT
dti-2192	196	1	obesity	obesity	NOUN
dti-2192	196	2	(	(	PUNCT
dti-2192	196	3	silver	silver	ADJ
dti-2192	196	4	spring	spring	NOUN
dti-2192	196	5	)	)	PUNCT
dti-2192	196	6	.	.	PUNCT
dti-2192	197	1	2020;28(6):1005	2020;28(6):1005	NUM
dti-2192	197	2	.	.	PUNCT
dti-2192	198	1	crossref	crossref	PROPN
dti-2192	198	2	pubmed	pubmed	PROPN
dti-2192	198	3	2	2	PROPN
dti-2192	198	4	.	.	PUNCT
dti-2192	199	1	jordan	jordan	PROPN
dti-2192	199	2	re	re	PROPN
dti-2192	199	3	,	,	PUNCT
dti-2192	199	4	adab	adab	NOUN
dti-2192	199	5	p	p	X
dti-2192	199	6	,	,	PUNCT
dti-2192	199	7	cheng	cheng	PROPN
dti-2192	199	8	kk	kk	PROPN
dti-2192	199	9	.	.	PUNCT
dti-2192	200	1	covid-19	covid-19	PROPN
dti-2192	200	2	:	:	PUNCT
dti-2192	200	3	risk	risk	NOUN
dti-2192	200	4	factors	factor	NOUN
dti-2192	200	5	for	for	ADP
dti-2192	200	6	severe	severe	ADJ
dti-2192	200	7	disease	disease	NOUN
dti-2192	200	8	and	and	CCONJ
dti-2192	200	9	death	death	NOUN
dti-2192	200	10	.	.	PUNCT
dti-2192	201	1	bmj	bmj	PROPN
dti-2192	201	2	.	.	PUNCT
dti-2192	202	1	2020;368(march):m1198	2020;368(march):m1198	NUM
dti-2192	202	2	.	.	PUNCT
dti-2192	203	1	crossref	crossref	PROPN
dti-2192	203	2	pubmed	pubmed	PROPN
dti-2192	203	3	3	3	PROPN
dti-2192	203	4	.	.	PUNCT
dti-2192	204	1	national	national	ADJ
dti-2192	204	2	academies	academy	NOUN
dti-2192	204	3	of	of	ADP
dti-2192	204	4	sciences	science	NOUN
dti-2192	204	5	and	and	CCONJ
dti-2192	204	6	medicine	medicine	NOUN
dti-2192	204	7	e	e	PROPN
dti-2192	204	8	,	,	PUNCT
dti-2192	204	9	national	national	ADJ
dti-2192	204	10	academies	academy	NOUN
dti-2192	204	11	of	of	ADP
dti-2192	204	12	sciences	science	NOUN
dti-2192	204	13	,	,	PUNCT
dti-2192	204	14	engineering	engineering	NOUN
dti-2192	204	15	and	and	CCONJ
dti-2192	204	16	m.	m.	NOUN
dti-2192	204	17	current	current	ADJ
dti-2192	204	18	status	status	NOUN
dti-2192	204	19	and	and	CCONJ
dti-2192	204	20	response	response	NOUN
dti-2192	204	21	to	to	ADP
dti-2192	204	22	the	the	DET
dti-2192	204	23	global	global	ADJ
dti-2192	204	24	obesity	obesity	NOUN
dti-2192	204	25	pandemic	pandemic	ADJ
dti-2192	204	26	:	:	PUNCT
dti-2192	204	27	proceedings	proceeding	NOUN
dti-2192	204	28	of	of	ADP
dti-2192	204	29	a	a	DET
dti-2192	204	30	workshop	workshop	NOUN
dti-2192	204	31	—	—	PUNCT
dti-2192	204	32	in	in	ADP
dti-2192	204	33	brief	brief	NOUN
dti-2192	204	34	.	.	PUNCT
dti-2192	205	1	(	(	PUNCT
dti-2192	205	2	callahan	callahan	PROPN
dti-2192	205	3	ea	ea	PROPN
dti-2192	205	4	,	,	PUNCT
dti-2192	205	5	ed	ed	NOUN
dti-2192	205	6	.	.	PUNCT
dti-2192	205	7	)	)	PUNCT
dti-2192	205	8	.	.	PUNCT
dti-2192	206	1	the	the	DET
dti-2192	206	2	national	national	PROPN
dti-2192	206	3	academies	academies	PROPN
dti-2192	206	4	press	press	PROPN
dti-2192	206	5	;	;	PUNCT
dti-2192	206	6	2019	2019	NUM
dti-2192	206	7	.	.	PUNCT
dti-2192	207	1	crossref	crossref	PROPN
dti-2192	207	2	4	4	NUM
dti-2192	207	3	.	.	PUNCT
dti-2192	207	4	del	del	PROPN
dti-2192	207	5	rio	rio	PROPN
dti-2192	207	6	c	c	PROPN
dti-2192	207	7	,	,	PUNCT
dti-2192	207	8	malani	malani	PROPN
dti-2192	207	9	pn	pn	PROPN
dti-2192	207	10	.	.	PUNCT
dti-2192	207	11	covid-19	covid-19	PROPN
dti-2192	207	12	—	—	PUNCT
dti-2192	207	13	new	new	ADJ
dti-2192	207	14	insights	insight	NOUN
dti-2192	207	15	on	on	ADP
dti-2192	207	16	a	a	DET
dti-2192	207	17	rapidly	rapidly	ADV
dti-2192	207	18	changing	change	VERB
dti-2192	207	19	epidemic	epidemic	NOUN
dti-2192	207	20	.	.	PUNCT
dti-2192	208	1	jama	jama	PROPN
dti-2192	208	2	.	.	PUNCT
dti-2192	209	1	2020;323(14):1339	2020;323(14):1339	NUM
dti-2192	209	2	-	-	SYM
dti-2192	209	3	1340	1340	NUM
dti-2192	209	4	.	.	PUNCT
dti-2192	210	1	crossref	crossref	PROPN
dti-2192	210	2	pubmed	pubmed	PROPN
dti-2192	210	3	5	5	NUM
dti-2192	210	4	.	.	PUNCT
dti-2192	211	1	gupta	gupta	PROPN
dti-2192	211	2	r	r	PROPN
dti-2192	211	3	,	,	PUNCT
dti-2192	211	4	ghosh	ghosh	PROPN
dti-2192	211	5	a	a	PROPN
dti-2192	211	6	,	,	PUNCT
dti-2192	211	7	singh	singh	PROPN
dti-2192	211	8	ak	ak	PROPN
dti-2192	211	9	,	,	PUNCT
dti-2192	211	10	misra	misra	ADJ
dti-2192	211	11	a.	a.	NOUN
dti-2192	211	12	clinical	clinical	ADJ
dti-2192	211	13	considerations	consideration	NOUN
dti-2192	211	14	for	for	ADP
dti-2192	211	15	patients	patient	NOUN
dti-2192	211	16	with	with	ADP
dti-2192	211	17	diabetes	diabetes	NOUN
dti-2192	211	18	in	in	ADP
dti-2192	211	19	times	time	NOUN
dti-2192	211	20	of	of	ADP
dti-2192	211	21	covid-19	covid-19	PROPN
dti-2192	211	22	epidemic	epidemic	NOUN
dti-2192	211	23	.	.	PUNCT
dti-2192	212	1	diabetes	diabete	VERB
dti-2192	212	2	metab	metab	NOUN
dti-2192	212	3	syndr	syndr	NOUN
dti-2192	212	4	.	.	PUNCT
dti-2192	213	1	2020;14(3):211	2020;14(3):211	NOUN
dti-2192	213	2	-	-	NUM
dti-2192	213	3	212	212	NUM
dti-2192	213	4	.	.	PUNCT
dti-2192	214	1	crossref	crossref	PROPN
dti-2192	214	2	pubmed	pubmed	PROPN
dti-2192	214	3	6	6	NUM
dti-2192	214	4	.	.	PUNCT
dti-2192	215	1	pachetti	pachetti	PROPN
dti-2192	215	2	m	m	PROPN
dti-2192	215	3	,	,	PUNCT
dti-2192	215	4	marini	marini	PROPN
dti-2192	215	5	b	b	PROPN
dti-2192	215	6	,	,	PUNCT
dti-2192	215	7	benedetti	benedetti	PROPN
dti-2192	215	8	f	f	PROPN
dti-2192	215	9	,	,	PUNCT
dti-2192	215	10	et	et	PROPN
dti-2192	215	11	al	al	PROPN
dti-2192	215	12	.	.	PUNCT
dti-2192	216	1	emerging	emerge	VERB
dti-2192	216	2	sars	sar	NOUN
dti-2192	216	3	-	-	PUNCT
dti-2192	216	4	cov-2	cov-2	NOUN
dti-2192	216	5	mutation	mutation	NOUN
dti-2192	216	6	hot	hot	ADJ
dti-2192	216	7	spots	spot	NOUN
dti-2192	216	8	include	include	VERB
dti-2192	216	9	a	a	DET
dti-2192	216	10	novel	novel	ADJ
dti-2192	216	11	rna	rna	NOUN
dti-2192	216	12	-	-	PUNCT
dti-2192	216	13	dependent	dependent	ADJ
dti-2192	216	14	-	-	PUNCT
dti-2192	216	15	rna	rna	NOUN
dti-2192	216	16	polymerase	polymerase	NOUN
dti-2192	216	17	variant	variant	NOUN
dti-2192	216	18	.	.	PUNCT
dti-2192	217	1	j	j	PROPN
dti-2192	217	2	transl	transl	PROPN
dti-2192	217	3	med	med	PROPN
dti-2192	217	4	.	.	PUNCT
dti-2192	218	1	2020;18(1):179	2020;18(1):179	PROPN
dti-2192	218	2	.	.	PUNCT
dti-2192	219	1	crossref	crossref	PROPN
dti-2192	219	2	pubmed	pubmed	PROPN
dti-2192	219	3	7	7	NUM
dti-2192	219	4	.	.	PUNCT
dti-2192	219	5	yao	yao	PROPN
dti-2192	220	1	x	x	SYM
dti-2192	220	2	,	,	PUNCT
dti-2192	220	3	ye	ye	PRON
dti-2192	220	4	f	f	PROPN
dti-2192	220	5	,	,	PUNCT
dti-2192	220	6	zhang	zhang	PROPN
dti-2192	220	7	m	m	PROPN
dti-2192	220	8	,	,	PUNCT
dti-2192	220	9	et	et	PROPN
dti-2192	220	10	al	al	PROPN
dti-2192	220	11	.	.	PUNCT
dti-2192	221	1	in	in	ADP
dti-2192	221	2	vitro	vitro	X
dti-2192	221	3	antiviral	antiviral	ADJ
dti-2192	221	4	activity	activity	NOUN
dti-2192	221	5	and	and	CCONJ
dti-2192	221	6	projection	projection	NOUN
dti-2192	221	7	of	of	ADP
dti-2192	221	8	optimized	optimize	VERB
dti-2192	221	9	dosing	dosing	NOUN
dti-2192	221	10	design	design	NOUN
dti-2192	221	11	of	of	ADP
dti-2192	221	12	hydroxychloroquine	hydroxychloroquine	NOUN
dti-2192	221	13	for	for	ADP
dti-2192	221	14	the	the	DET
dti-2192	221	15	treatment	treatment	NOUN
dti-2192	221	16	of	of	ADP
dti-2192	221	17	severe	severe	ADJ
dti-2192	221	18	acute	acute	ADJ
dti-2192	221	19	respiratory	respiratory	ADJ
dti-2192	221	20	syndrome	syndrome	NOUN
dti-2192	221	21	main	main	ADJ
dti-2192	221	22	point	point	NOUN
dti-2192	221	23	:	:	PUNCT
dti-2192	221	24	hydroxychloroquine	hydroxychloroquine	PROPN
dti-2192	221	25	was	be	AUX
dti-2192	221	26	found	find	VERB
dti-2192	221	27	to	to	PART
dti-2192	221	28	be	be	AUX
dti-2192	221	29	more	more	ADV
dti-2192	221	30	potent	potent	ADJ
dti-2192	221	31	than	than	ADP
dti-2192	221	32	chloroquine	chloroquine	NOUN
dti-2192	221	33	at	at	ADP
dti-2192	221	34	inhibiting	inhibit	VERB
dti-2192	221	35	sars	sar	NOUN
dti-2192	221	36	-	-	PUNCT
dti-2192	221	37	cov-2	cov-2	NOUN
dti-2192	221	38	in	in	ADP
dti-2192	221	39	vit	vit	PROPN
dti-2192	221	40	.	.	PUNCT
dti-2192	222	1	clin	clin	PROPN
dti-2192	222	2	infect	infect	PROPN
dti-2192	222	3	dis	dis	PROPN
dti-2192	222	4	.	.	PUNCT
dti-2192	223	1	2020;2	2020;2	NUM
dti-2192	223	2	:	:	PUNCT
dti-2192	224	1	1	1	NUM
dti-2192	224	2	-	-	SYM
dti-2192	224	3	25	25	NUM
dti-2192	224	4	.	.	NOUN
dti-2192	224	5	8	8	NUM
dti-2192	224	6	.	.	PUNCT
dti-2192	225	1	calder	calder	PROPN
dti-2192	225	2	pc	pc	PROPN
dti-2192	225	3	,	,	PUNCT
dti-2192	225	4	waitzberg	waitzberg	PROPN
dti-2192	225	5	dl	dl	PROPN
dti-2192	225	6	,	,	PUNCT
dti-2192	225	7	klek	klek	PROPN
dti-2192	225	8	s	s	PROPN
dti-2192	225	9	,	,	PUNCT
dti-2192	225	10	martindale	martindale	PROPN
dti-2192	225	11	rg	rg	PROPN
dti-2192	225	12	.	.	PROPN
dti-2192	225	13	lipids	lipid	NOUN
dti-2192	225	14	in	in	ADP
dti-2192	225	15	parenteral	parenteral	ADJ
dti-2192	225	16	nutrition	nutrition	NOUN
dti-2192	225	17	:	:	PUNCT
dti-2192	225	18	biological	biological	ADJ
dti-2192	225	19	aspects	aspect	NOUN
dti-2192	225	20	.	.	PUNCT
dti-2192	226	1	jpen	jpen	PROPN
dti-2192	226	2	j	j	PROPN
dti-2192	226	3	parenter	parenter	PROPN
dti-2192	226	4	enteral	enteral	ADJ
dti-2192	226	5	nutr	nutr	NOUN
dti-2192	226	6	.	.	PUNCT
dti-2192	227	1	2020;44(s1)(suppl	2020;44(s1)(suppl	ADJ
dti-2192	227	2	1):s21	1):s21	PROPN
dti-2192	227	3	-	-	PUNCT
dti-2192	227	4	s27	s27	PROPN
dti-2192	227	5	.	.	PUNCT
dti-2192	228	1	crossref	crossref	PROPN
dti-2192	228	2	pubmed	pubmed	PROPN
dti-2192	228	3	9	9	PROPN
dti-2192	228	4	.	.	PUNCT
dti-2192	229	1	bornstein	bornstein	PROPN
dti-2192	229	2	sr	sr	PROPN
dti-2192	229	3	,	,	PUNCT
dti-2192	229	4	dalan	dalan	PROPN
dti-2192	229	5	r	r	NOUN
dti-2192	229	6	,	,	PUNCT
dti-2192	229	7	hopkins	hopkins	PROPN
dti-2192	229	8	d	d	PROPN
dti-2192	229	9	,	,	PUNCT
dti-2192	229	10	mingrone	mingrone	NOUN
dti-2192	229	11	g	g	NOUN
dti-2192	229	12	,	,	PUNCT
dti-2192	229	13	boehm	boehm	PROPN
dti-2192	229	14	bo	bo	PROPN
dti-2192	229	15	.	.	PROPN
dti-2192	229	16	endocrine	endocrine	PROPN
dti-2192	229	17	and	and	CCONJ
dti-2192	229	18	metabolic	metabolic	NOUN
dti-2192	229	19	link	link	NOUN
dti-2192	229	20	to	to	ADP
dti-2192	229	21	coronavirus	coronavirus	NOUN
dti-2192	229	22	infection	infection	NOUN
dti-2192	229	23	.	.	PUNCT
dti-2192	230	1	nat	nat	PROPN
dti-2192	230	2	rev	rev	PROPN
dti-2192	230	3	endocrinol	endocrinol	NOUN
dti-2192	230	4	.	.	PUNCT
dti-2192	231	1	2020;16(6):297	2020;16(6):297	NUM
dti-2192	231	2	-	-	PUNCT
dti-2192	231	3	298	298	NUM
dti-2192	231	4	.	.	PUNCT
dti-2192	232	1	crossref	crossref	PROPN
dti-2192	232	2	pubmed	pubmed	PROPN
dti-2192	232	3	10	10	PROPN
dti-2192	232	4	.	.	PUNCT
dti-2192	233	1	ryan	ryan	PROPN
dti-2192	233	2	dh	dh	PROPN
dti-2192	233	3	,	,	PUNCT
dti-2192	233	4	ravussin	ravussin	NOUN
dti-2192	233	5	e	e	NOUN
dti-2192	233	6	,	,	PUNCT
dti-2192	233	7	heymsfield	heymsfield	PROPN
dti-2192	233	8	s.	s.	PROPN
dti-2192	233	9	covid	covid	PROPN
dti-2192	233	10	19	19	NUM
dti-2192	233	11	and	and	CCONJ
dti-2192	233	12	the	the	DET
dti-2192	233	13	patient	patient	NOUN
dti-2192	233	14	with	with	ADP
dti-2192	233	15	obesity	obesity	NOUN
dti-2192	233	16	—	—	PUNCT
dti-2192	233	17	the	the	DET
dti-2192	233	18	editors	editor	NOUN
dti-2192	233	19	speak	speak	VERB
dti-2192	233	20	out	out	ADP
dti-2192	233	21	.	.	PUNCT
dti-2192	234	1	obesity	obesity	NOUN
dti-2192	234	2	(	(	PUNCT
dti-2192	234	3	silver	silver	ADJ
dti-2192	234	4	spring	spring	NOUN
dti-2192	234	5	)	)	PUNCT
dti-2192	234	6	.	.	PUNCT
dti-2192	235	1	2020;28(5):847	2020;28(5):847	NOUN
dti-2192	235	2	.	.	PUNCT
dti-2192	236	1	crossref	crossref	PROPN
dti-2192	236	2	pubmed	pubmed	PROPN
dti-2192	236	3	11	11	NUM
dti-2192	236	4	.	.	PUNCT
dti-2192	237	1	butler	butler	PROPN
dti-2192	237	2	cc	cc	PROPN
dti-2192	237	3	,	,	PUNCT
dti-2192	237	4	van	van	PROPN
dti-2192	237	5	der	der	PROPN
dti-2192	237	6	velden	velden	PROPN
dti-2192	237	7	aw	aw	PROPN
dti-2192	237	8	,	,	PUNCT
dti-2192	237	9	bongard	bongard	NOUN
dti-2192	237	10	e	e	NOUN
dti-2192	237	11	,	,	PUNCT
dti-2192	237	12	et	et	PROPN
dti-2192	237	13	al	al	PROPN
dti-2192	237	14	.	.	PUNCT
dti-2192	238	1	oseltamivir	oseltamivir	PROPN
dti-2192	238	2	plus	plus	CCONJ
dti-2192	238	3	usual	usual	ADJ
dti-2192	238	4	care	care	NOUN
dti-2192	238	5	versus	versus	ADP
dti-2192	238	6	usual	usual	ADJ
dti-2192	238	7	care	care	NOUN
dti-2192	238	8	for	for	ADP
dti-2192	238	9	influenza	influenza	NOUN
dti-2192	238	10	-	-	PUNCT
dti-2192	238	11	like	like	ADJ
dti-2192	238	12	illness	illness	NOUN
dti-2192	238	13	in	in	ADP
dti-2192	238	14	primary	primary	ADJ
dti-2192	238	15	care	care	NOUN
dti-2192	238	16	:	:	PUNCT
dti-2192	238	17	an	an	DET
dti-2192	238	18	open	open	ADJ
dti-2192	238	19	-	-	PUNCT
dti-2192	238	20	label	label	NOUN
dti-2192	238	21	,	,	PUNCT
dti-2192	238	22	pragmatic	pragmatic	ADJ
dti-2192	238	23	,	,	PUNCT
dti-2192	238	24	randomised	randomise	VERB
dti-2192	238	25	controlled	control	VERB
dti-2192	238	26	trial	trial	NOUN
dti-2192	238	27	.	.	PUNCT
dti-2192	239	1	lancet	lancet	NOUN
dti-2192	239	2	.	.	PUNCT
dti-2192	240	1	2020;395(10217):42	2020;395(10217):42	ADJ
dti-2192	240	2	-	-	SYM
dti-2192	240	3	52	52	NUM
dti-2192	240	4	.	.	PUNCT
dti-2192	241	1	crossref	crossref	PROPN
dti-2192	241	2	pubmed	pubmed	PROPN
dti-2192	241	3	12	12	NUM
dti-2192	241	4	.	.	PUNCT
dti-2192	242	1	muscogiuri	muscogiuri	PROPN
dti-2192	242	2	g	g	PROPN
dti-2192	242	3	,	,	PUNCT
dti-2192	242	4	barrea	barrea	PROPN
dti-2192	242	5	l	l	PROPN
dti-2192	242	6	,	,	PUNCT
dti-2192	242	7	savastano	savastano	PROPN
dti-2192	242	8	s	s	PART
dti-2192	242	9	,	,	PUNCT
dti-2192	242	10	colao	colao	VERB
dti-2192	242	11	a.	a.	NOUN
dti-2192	242	12	nutritional	nutritional	ADJ
dti-2192	242	13	recommendations	recommendation	NOUN
dti-2192	242	14	for	for	ADP
dti-2192	242	15	covid-19	covid-19	PROPN
dti-2192	242	16	quarantine	quarantine	NOUN
dti-2192	242	17	.	.	PUNCT
dti-2192	243	1	eur	eur	PROPN
dti-2192	243	2	j	j	PROPN
dti-2192	243	3	clin	clin	PROPN
dti-2192	243	4	nutr	nutr	PROPN
dti-2192	243	5	.	.	PROPN
dti-2192	243	6	published	publish	VERB
dti-2192	243	7	online	online	ADJ
dti-2192	243	8	2020:10	2020:10	NUM
dti-2192	243	9	-	-	SYM
dti-2192	243	10	11	11	NUM
dti-2192	243	11	.	.	PUNCT
dti-2192	244	1	crossref	crossref	PROPN
dti-2192	244	2	13	13	NUM
dti-2192	244	3	.	.	PUNCT
dti-2192	245	1	united	united	PROPN
dti-2192	245	2	nations	nations	PROPN
dti-2192	245	3	system	system	PROPN
dti-2192	245	4	standing	standing	PROPN
dti-2192	245	5	committee	committee	PROPN
dti-2192	245	6	on	on	ADP
dti-2192	245	7	nutrition	nutrition	NOUN
dti-2192	245	8	—	—	PUNCT
dti-2192	246	1	unscn	unscn	ADJ
dti-2192	246	2	.	.	PUNCT
dti-2192	247	1	food	food	NOUN
dti-2192	247	2	environments	environment	NOUN
dti-2192	247	3	in	in	ADP
dti-2192	247	4	the	the	DET
dti-2192	247	5	covid-19	covid-19	PROPN
dti-2192	247	6	pandemic	pandemic	NOUN
dti-2192	247	7	.	.	PUNCT
dti-2192	248	1	unscn	unscn	PROPN
dti-2192	248	2	.	.	PUNCT
dti-2192	249	1	published	publish	VERB
dti-2192	249	2	2020	2020	NUM
dti-2192	249	3	.	.	PUNCT
dti-2192	250	1	online	online	INTJ
dti-2192	250	2	.	.	PUNCT
dti-2192	251	1	accessed	access	VERB
dti-2192	251	2	april	april	PROPN
dti-2192	251	3	29	29	NUM
dti-2192	251	4	,	,	PUNCT
dti-2192	251	5	2020	2020	NUM
dti-2192	251	6	.	.	PUNCT
dti-2192	252	1	14	14	NUM
dti-2192	252	2	.	.	PUNCT
dti-2192	252	3	rundle	rundle	PROPN
dti-2192	252	4	ag	ag	PROPN
dti-2192	252	5	,	,	PUNCT
dti-2192	252	6	park	park	NOUN
dti-2192	252	7	y	y	PROPN
dti-2192	252	8	,	,	PUNCT
dti-2192	252	9	herbstman	herbstman	NOUN
dti-2192	252	10	jb	jb	PROPN
dti-2192	252	11	,	,	PUNCT
dti-2192	252	12	kinsey	kinsey	PROPN
dti-2192	252	13	ew	ew	PROPN
dti-2192	252	14	,	,	PUNCT
dti-2192	252	15	wang	wang	PROPN
dti-2192	252	16	yc	yc	PROPN
dti-2192	252	17	.	.	PUNCT
dti-2192	252	18	covid19	covid19	NOUN
dti-2192	252	19	-	-	PUNCT
dti-2192	252	20	related	relate	VERB
dti-2192	252	21	school	school	NOUN
dti-2192	252	22	closings	closing	NOUN
dti-2192	252	23	and	and	CCONJ
dti-2192	252	24	risk	risk	NOUN
dti-2192	252	25	of	of	ADP
dti-2192	252	26	weight	weight	NOUN
dti-2192	252	27	gain	gain	NOUN
dti-2192	252	28	among	among	ADP
dti-2192	252	29	children	child	NOUN
dti-2192	252	30	.	.	PUNCT
dti-2192	253	1	obesity	obesity	NOUN
dti-2192	253	2	(	(	PUNCT
dti-2192	253	3	silver	silver	ADJ
dti-2192	253	4	spring	spring	NOUN
dti-2192	253	5	)	)	PUNCT
dti-2192	253	6	.	.	PUNCT
dti-2192	254	1	2020;28(6):1008	2020;28(6):1008	NOUN
dti-2192	254	2	-	-	PUNCT
dti-2192	254	3	1009	1009	NUM
dti-2192	254	4	.	.	PUNCT
dti-2192	255	1	crossref	crossref	PROPN
dti-2192	255	2	pubmed	pubmed	PROPN
dti-2192	255	3	15	15	PROPN
dti-2192	255	4	.	.	PUNCT
dti-2192	256	1	berger	berger	PROPN
dti-2192	256	2	zd	zd	PROPN
dti-2192	256	3	,	,	PUNCT
dti-2192	256	4	evans	evans	PROPN
dti-2192	256	5	ng	ng	PROPN
dti-2192	256	6	,	,	PUNCT
dti-2192	256	7	phelan	phelan	PROPN
dti-2192	256	8	al	al	PROPN
dti-2192	256	9	,	,	PUNCT
dti-2192	256	10	silverman	silverman	PROPN
dti-2192	256	11	rd	rd	PROPN
dti-2192	256	12	.	.	PUNCT
dti-2192	257	1	covid-19	covid-19	PROPN
dti-2192	257	2	:	:	PUNCT
dti-2192	257	3	control	control	NOUN
dti-2192	257	4	measures	measure	NOUN
dti-2192	257	5	must	must	AUX
dti-2192	257	6	be	be	AUX
dti-2192	257	7	equitable	equitable	ADJ
dti-2192	257	8	and	and	CCONJ
dti-2192	257	9	inclusive	inclusive	ADJ
dti-2192	257	10	.	.	PUNCT
dti-2192	258	1	bmj	bmj	PROPN
dti-2192	258	2	.	.	PUNCT
dti-2192	259	1	2020;368(sept	2020;368(sept	NUM
dti-2192	259	2	2001):m1141	2001):m1141	NUM
dti-2192	259	3	.	.	PUNCT
dti-2192	260	1	crossref	crossref	PROPN
dti-2192	260	2	https://doi.org/10.1002/oby.22818	https://doi.org/10.1002/oby.22818	PROPN
dti-2192	260	3	https://www.ncbi.nlm.nih.gov/pubmed/32237206	https://www.ncbi.nlm.nih.gov/pubmed/32237206	ADV
dti-2192	260	4	https://doi.org/10.1136/bmj.m1198	https://doi.org/10.1136/bmj.m1198	ADJ
dti-2192	260	5	https://www.ncbi.nlm.nih.gov/pubmed/32217618	https://www.ncbi.nlm.nih.gov/pubmed/32217618	ADP
dti-2192	260	6	https://doi.org/10.17226/25349	https://doi.org/10.17226/25349	NOUN
dti-2192	260	7	https://www.ncbi.nlm.nih.gov/pubmed/32108857	https://www.ncbi.nlm.nih.gov/pubmed/32108857	PRON
dti-2192	260	8	https://doi.org/10.1001/jama.2020.3072	https://doi.org/10.1001/jama.2020.3072	PROPN
dti-2192	260	9	https://doi.org/10.1016/j.dsx.2020.03.002	https://doi.org/10.1016/j.dsx.2020.03.002	NOUN
dti-2192	260	10	https://www.ncbi.nlm.nih.gov/pubmed/32172175	https://www.ncbi.nlm.nih.gov/pubmed/32172175	PRON
dti-2192	260	11	https://www.ncbi.nlm.nih.gov/pubmed/32321524	https://www.ncbi.nlm.nih.gov/pubmed/32321524	PROPN
dti-2192	260	12	https://doi.org/10.1186/s12967-020-02344-6	https://doi.org/10.1186/s12967-020-02344-6	NUM
dti-2192	260	13	https://doi.org/10.1002/jpen.1756	https://doi.org/10.1002/jpen.1756	NOUN
dti-2192	260	14	https://www.ncbi.nlm.nih.gov/pubmed/32049394	https://www.ncbi.nlm.nih.gov/pubmed/32049394	NUM
dti-2192	260	15	https://doi.org/10.1038/s41574-020-0353-9	https://doi.org/10.1038/s41574-020-0353-9	PROPN
dti-2192	260	16	https://www.ncbi.nlm.nih.gov/pubmed/32242089	https://www.ncbi.nlm.nih.gov/pubmed/32242089	NUM
dti-2192	260	17	https://doi.org/10.1002/oby.22808	https://doi.org/10.1002/oby.22808	PROPN
dti-2192	260	18	https://www.ncbi.nlm.nih.gov/pubmed/32237212	https://www.ncbi.nlm.nih.gov/pubmed/32237212	NUM
dti-2192	260	19	https://doi.org/10.1016/s0140-6736(19)32982-4	https://doi.org/10.1016/s0140-6736(19)32982-4	PROPN
dti-2192	260	20	https://www.ncbi.nlm.nih.gov/pubmed/31839279	https://www.ncbi.nlm.nih.gov/pubmed/31839279	PROPN
dti-2192	260	21	https://doi.org/10.1038/s41430-020-0635-2	https://doi.org/10.1038/s41430-020-0635-2	PROPN
dti-2192	260	22	https://www.unscn.org/en/news-events/recent-news?idnews=2040	https://www.unscn.org/en/news-events/recent-news?idnews=2040	NOUN
dti-2192	260	23	https://doi.org/10.1002/oby.22813	https://doi.org/10.1002/oby.22813	PROPN
dti-2192	260	24	https://www.ncbi.nlm.nih.gov/pubmed/32227671	https://www.ncbi.nlm.nih.gov/pubmed/32227671	PROPN
dti-2192	260	25	https://doi.org/10.1136/bmj.m1141	https://doi.org/10.1136/bmj.m1141	NUM
dti-2192	260	26	morais	morais	PROPN
dti-2192	260	27	et	et	PROPN
dti-2192	260	28	al	al	PROPN
dti-2192	260	29	drug	drug	PROPN
dti-2192	260	30	target	target	NOUN
dti-2192	260	31	insights	insight	NOUN
dti-2192	260	32	2021	2021	NUM
dti-2192	260	33	;	;	PUNCT
dti-2192	260	34	15	15	NUM
dti-2192	260	35	:	:	SYM
dti-2192	260	36	11	11	NUM
dti-2192	260	37	©	©	PROPN
dti-2192	260	38	2021	2021	NUM
dti-2192	260	39	the	the	DET
dti-2192	260	40	authors	author	NOUN
dti-2192	260	41	.	.	PUNCT
dti-2192	261	1	published	publish	VERB
dti-2192	261	2	by	by	ADP
dti-2192	261	3	aboutscience	aboutscience	NOUN
dti-2192	261	4	www.aboutscience.eu	www.aboutscience.eu	PROPN
dti-2192	261	5	16	16	NUM
dti-2192	261	6	.	.	PUNCT
dti-2192	262	1	farrell	farrell	PROPN
dti-2192	262	2	p	p	PROPN
dti-2192	262	3	,	,	PUNCT
dti-2192	262	4	thow	thow	ADV
dti-2192	262	5	am	be	AUX
dti-2192	262	6	,	,	PUNCT
dti-2192	262	7	abimbola	abimbola	PROPN
dti-2192	262	8	s	s	PROPN
dti-2192	262	9	,	,	PUNCT
dti-2192	262	10	faruqui	faruqui	NOUN
dti-2192	262	11	n	n	CCONJ
dti-2192	262	12	,	,	PUNCT
dti-2192	262	13	negin	negin	PROPN
dti-2192	262	14	j.	j.	PROPN
dti-2192	263	1	how	how	SCONJ
dti-2192	263	2	food	food	NOUN
dti-2192	263	3	insecurity	insecurity	NOUN
dti-2192	263	4	could	could	AUX
dti-2192	263	5	lead	lead	VERB
dti-2192	263	6	to	to	ADP
dti-2192	263	7	obesity	obesity	NOUN
dti-2192	263	8	in	in	ADP
dti-2192	263	9	lmics	lmic	NOUN
dti-2192	263	10	:	:	PUNCT
dti-2192	263	11	when	when	SCONJ
dti-2192	263	12	not	not	PART
dti-2192	263	13	enough	enough	ADV
dti-2192	263	14	is	be	AUX
dti-2192	263	15	too	too	ADV
dti-2192	263	16	much	much	ADJ
dti-2192	263	17	:	:	PUNCT
dti-2192	263	18	a	a	DET
dti-2192	263	19	realist	realist	ADJ
dti-2192	263	20	review	review	NOUN
dti-2192	263	21	of	of	ADP
dti-2192	263	22	how	how	SCONJ
dti-2192	263	23	food	food	NOUN
dti-2192	263	24	insecurity	insecurity	NOUN
dti-2192	263	25	could	could	AUX
dti-2192	263	26	lead	lead	VERB
dti-2192	263	27	to	to	ADP
dti-2192	263	28	obesity	obesity	NOUN
dti-2192	263	29	in	in	ADP
dti-2192	263	30	lowand	lowand	ADJ
dti-2192	263	31	middle	middle	ADJ
dti-2192	263	32	-	-	PUNCT
dti-2192	263	33	income	income	NOUN
dti-2192	263	34	countries	country	NOUN
dti-2192	263	35	.	.	PUNCT
dti-2192	264	1	health	health	NOUN
dti-2192	264	2	promot	promot	PROPN
dti-2192	264	3	int	int	NOUN
dti-2192	264	4	.	.	PUNCT
dti-2192	265	1	2018;33(5):812	2018;33(5):812	NUM
dti-2192	265	2	-	-	PUNCT
dti-2192	265	3	826	826	NUM
dti-2192	265	4	.	.	PUNCT
dti-2192	266	1	crossref	crossref	PROPN
dti-2192	266	2	pubmed	pubmed	PROPN
dti-2192	266	3	17	17	NUM
dti-2192	266	4	.	.	PUNCT
dti-2192	267	1	kissler	kissler	PROPN
dti-2192	267	2	sm	sm	PROPN
dti-2192	267	3	,	,	PUNCT
dti-2192	267	4	tedijanto	tedijanto	ADP
dti-2192	267	5	c	c	PROPN
dti-2192	267	6	,	,	PUNCT
dti-2192	267	7	goldstein	goldstein	PROPN
dti-2192	267	8	e	e	PROPN
dti-2192	267	9	,	,	PUNCT
dti-2192	267	10	grad	grad	PROPN
dti-2192	267	11	yh	yh	PROPN
dti-2192	267	12	,	,	PUNCT
dti-2192	267	13	lipsitch	lipsitch	VERB
dti-2192	267	14	m.	m.	NOUN
dti-2192	267	15	projecting	project	VERB
dti-2192	267	16	the	the	DET
dti-2192	267	17	transmission	transmission	NOUN
dti-2192	267	18	dynamics	dynamic	NOUN
dti-2192	267	19	of	of	ADP
dti-2192	267	20	sars	sar	NOUN
dti-2192	267	21	-	-	PUNCT
dti-2192	267	22	cov-2	cov-2	NOUN
dti-2192	267	23	through	through	ADP
dti-2192	267	24	the	the	DET
dti-2192	267	25	postpandemic	postpandemic	ADJ
dti-2192	267	26	period	period	NOUN
dti-2192	267	27	.	.	PUNCT
dti-2192	268	1	science	science	NOUN
dti-2192	268	2	.	.	PUNCT
dti-2192	269	1	2020;5793(february	2020;5793(february	PROPN
dti-2192	269	2	2019):eabb5793	2019):eabb5793	NUM
dti-2192	269	3	.	.	PUNCT
dti-2192	270	1	crossref	crossref	PROPN
dti-2192	270	2	18	18	NUM
dti-2192	270	3	.	.	PUNCT
dti-2192	271	1	pindjakova	pindjakova	PROPN
dti-2192	271	2	j	j	PROPN
dti-2192	271	3	,	,	PUNCT
dti-2192	271	4	sartini	sartini	PROPN
dti-2192	271	5	c	c	PROPN
dti-2192	271	6	,	,	PUNCT
dti-2192	271	7	lo	lo	PROPN
dti-2192	271	8	re	re	NOUN
dti-2192	271	9	o	o	PROPN
dti-2192	271	10	,	,	PUNCT
dti-2192	271	11	et	et	PROPN
dti-2192	271	12	al	al	PROPN
dti-2192	271	13	.	.	PUNCT
dti-2192	272	1	gut	gut	VERB
dti-2192	272	2	dysbiosis	dysbiosis	NOUN
dti-2192	272	3	and	and	CCONJ
dti-2192	272	4	adaptive	adaptive	ADJ
dti-2192	272	5	immune	immune	ADJ
dti-2192	272	6	response	response	NOUN
dti-2192	272	7	in	in	ADP
dti-2192	272	8	diet	diet	NOUN
dti-2192	272	9	-	-	PUNCT
dti-2192	272	10	induced	induce	VERB
dti-2192	272	11	obesity	obesity	NOUN
dti-2192	272	12	vs.	vs.	ADP
dti-2192	272	13	systemic	systemic	ADJ
dti-2192	272	14	inflammation	inflammation	NOUN
dti-2192	272	15	.	.	PUNCT
dti-2192	273	1	front	front	ADJ
dti-2192	273	2	microbiol	microbiol	PROPN
dti-2192	273	3	.	.	PUNCT
dti-2192	274	1	2017;8(jun):1157	2017;8(jun):1157	NUM
dti-2192	274	2	.	.	PUNCT
dti-2192	275	1	crossref	crossref	PROPN
dti-2192	275	2	pubmed	pubmed	PROPN
dti-2192	275	3	19	19	NUM
dti-2192	275	4	.	.	PUNCT
dti-2192	276	1	dixon	dixon	PROPN
dti-2192	276	2	ae	ae	PROPN
dti-2192	276	3	,	,	PUNCT
dti-2192	276	4	peters	peters	PROPN
dti-2192	276	5	u.	u.	VERB
dti-2192	276	6	the	the	DET
dti-2192	276	7	effect	effect	NOUN
dti-2192	276	8	of	of	ADP
dti-2192	276	9	obesity	obesity	NOUN
dti-2192	276	10	on	on	ADP
dti-2192	276	11	lung	lung	NOUN
dti-2192	276	12	function	function	NOUN
dti-2192	276	13	.	.	PUNCT
dti-2192	277	1	expert	expert	NOUN
dti-2192	277	2	rev	rev	AUX
dti-2192	277	3	respir	respir	VERB
dti-2192	277	4	med	me	VERB
dti-2192	277	5	.	.	PUNCT
dti-2192	278	1	2018;12(9):755	2018;12(9):755	PROPN
dti-2192	278	2	-	-	PUNCT
dti-2192	278	3	767	767	NUM
dti-2192	278	4	.	.	PUNCT
dti-2192	279	1	crossref	crossref	PROPN
dti-2192	279	2	pubmed	pubmed	PROPN
dti-2192	279	3	20	20	PROPN
dti-2192	279	4	.	.	PUNCT
dti-2192	280	1	johnson	johnson	PROPN
dti-2192	280	2	ar	ar	PROPN
dti-2192	280	3	,	,	PUNCT
dti-2192	280	4	milner	milner	PROPN
dti-2192	280	5	jj	jj	PROPN
dti-2192	280	6	,	,	PUNCT
dti-2192	280	7	makowski	makowski	PROPN
dti-2192	280	8	l.	l.	PROPN
dti-2192	280	9	the	the	DET
dti-2192	280	10	inflammation	inflammation	ADJ
dti-2192	280	11	highway	highway	NOUN
dti-2192	280	12	:	:	PUNCT
dti-2192	280	13	metabolism	metabolism	NOUN
dti-2192	280	14	accelerates	accelerate	VERB
dti-2192	280	15	inflammatory	inflammatory	ADJ
dti-2192	280	16	traffic	traffic	NOUN
dti-2192	280	17	in	in	ADP
dti-2192	280	18	obesity	obesity	NOUN
dti-2192	280	19	.	.	PUNCT
dti-2192	281	1	immunol	immunol	PROPN
dti-2192	281	2	rev	rev	PROPN
dti-2192	281	3	.	.	PROPN
dti-2192	281	4	2012;249(1):218	2012;249(1):218	NUM
dti-2192	281	5	-	-	NOUN
dti-2192	281	6	238	238	NUM
dti-2192	281	7	.	.	PUNCT
dti-2192	282	1	crossref	crossref	PROPN
dti-2192	282	2	pubmed	pubmed	PROPN
dti-2192	282	3	21	21	NUM
dti-2192	282	4	.	.	PUNCT
dti-2192	283	1	kassir	kassir	PROPN
dti-2192	283	2	r.	r.	PROPN
dti-2192	283	3	risk	risk	NOUN
dti-2192	283	4	of	of	ADP
dti-2192	283	5	covid-19	covid-19	PROPN
dti-2192	283	6	for	for	ADP
dti-2192	283	7	patients	patient	NOUN
dti-2192	283	8	with	with	ADP
dti-2192	283	9	obesity	obesity	NOUN
dti-2192	283	10	.	.	PUNCT
dti-2192	284	1	obes	obes	PROPN
dti-2192	284	2	rev	rev	VERB
dti-2192	284	3	.	.	PUNCT
dti-2192	285	1	2020;21(6):e13034	2020;21(6):e13034	X
dti-2192	285	2	.	.	PUNCT
dti-2192	285	3	crossref	crossref	PROPN
dti-2192	285	4	pubmed	pubmed	PROPN
dti-2192	285	5	22	22	NUM
dti-2192	285	6	.	.	PUNCT
dti-2192	286	1	stefan	stefan	PROPN
dti-2192	286	2	n.	n.	PROPN
dti-2192	286	3	causes	cause	NOUN
dti-2192	286	4	,	,	PUNCT
dti-2192	286	5	consequences	consequence	NOUN
dti-2192	286	6	,	,	PUNCT
dti-2192	286	7	and	and	CCONJ
dti-2192	286	8	treatment	treatment	NOUN
dti-2192	286	9	of	of	ADP
dti-2192	286	10	metabolically	metabolically	ADV
dti-2192	286	11	unhealthy	unhealthy	ADJ
dti-2192	286	12	fat	fat	ADJ
dti-2192	286	13	distribution	distribution	NOUN
dti-2192	286	14	.	.	PUNCT
dti-2192	287	1	lancet	lancet	NOUN
dti-2192	287	2	diabetes	diabetes	NOUN
dti-2192	287	3	endocrinol	endocrinol	NOUN
dti-2192	287	4	.	.	PUNCT
dti-2192	288	1	2020;8(7):616	2020;8(7):616	X
dti-2192	288	2	-	-	PUNCT
dti-2192	288	3	627	627	NUM
dti-2192	288	4	.	.	PUNCT
dti-2192	289	1	crossref	crossref	PROPN
dti-2192	289	2	pubmed	pubmed	PROPN
dti-2192	289	3	23	23	NUM
dti-2192	289	4	.	.	PUNCT
dti-2192	290	1	stefan	stefan	PROPN
dti-2192	290	2	n	n	PROPN
dti-2192	290	3	,	,	PUNCT
dti-2192	290	4	birkenfeld	birkenfeld	PROPN
dti-2192	290	5	al	al	PROPN
dti-2192	290	6	,	,	PUNCT
dti-2192	290	7	schulze	schulze	NOUN
dti-2192	290	8	mb	mb	PROPN
dti-2192	290	9	.	.	PUNCT
dti-2192	291	1	global	global	ADJ
dti-2192	291	2	pandemics	pandemic	NOUN
dti-2192	291	3	interconnected	interconnect	VERB
dti-2192	291	4	—	—	PUNCT
dti-2192	291	5	obesity	obesity	NOUN
dti-2192	291	6	,	,	PUNCT
dti-2192	291	7	impaired	impaired	ADJ
dti-2192	291	8	metabolic	metabolic	NOUN
dti-2192	291	9	health	health	NOUN
dti-2192	291	10	and	and	CCONJ
dti-2192	291	11	covid-19	covid-19	PROPN
dti-2192	291	12	.	.	PUNCT
dti-2192	292	1	nat	nat	PROPN
dti-2192	292	2	rev	rev	PROPN
dti-2192	292	3	endocrinol	endocrinol	NOUN
dti-2192	292	4	.	.	PUNCT
dti-2192	293	1	2021;17(3):135	2021;17(3):135	NOUN
dti-2192	293	2	-	-	SYM
dti-2192	293	3	149	149	NUM
dti-2192	293	4	.	.	PUNCT
dti-2192	294	1	crossref	crossref	PROPN
dti-2192	294	2	pubmed	pubmed	PROPN
dti-2192	294	3	24	24	NUM
dti-2192	294	4	.	.	PUNCT
dti-2192	295	1	petersen	petersen	PROPN
dti-2192	295	2	a	a	DET
dti-2192	295	3	,	,	PUNCT
dti-2192	295	4	bressem	bressem	PROPN
dti-2192	295	5	k	k	PROPN
dti-2192	295	6	,	,	PUNCT
dti-2192	295	7	albrecht	albrecht	PROPN
dti-2192	295	8	j	j	PROPN
dti-2192	295	9	,	,	PUNCT
dti-2192	295	10	et	et	PROPN
dti-2192	295	11	al	al	PROPN
dti-2192	295	12	.	.	PUNCT
dti-2192	296	1	the	the	DET
dti-2192	296	2	role	role	NOUN
dti-2192	296	3	of	of	ADP
dti-2192	296	4	visceral	visceral	ADJ
dti-2192	296	5	adiposity	adiposity	NOUN
dti-2192	296	6	in	in	ADP
dti-2192	296	7	the	the	DET
dti-2192	296	8	severity	severity	NOUN
dti-2192	296	9	of	of	ADP
dti-2192	296	10	covid-19	covid-19	PROPN
dti-2192	296	11	:	:	PUNCT
dti-2192	296	12	highlights	highlight	NOUN
dti-2192	296	13	from	from	ADP
dti-2192	296	14	a	a	DET
dti-2192	296	15	unicenter	unicenter	NOUN
dti-2192	296	16	cross	cross	ADJ
dti-2192	296	17	-	-	ADJ
dti-2192	296	18	sectional	sectional	ADJ
dti-2192	296	19	pilot	pilot	NOUN
dti-2192	296	20	study	study	NOUN
dti-2192	296	21	in	in	ADP
dti-2192	296	22	germany	germany	PROPN
dti-2192	296	23	.	.	PUNCT
dti-2192	297	1	metabolism	metabolism	NOUN
dti-2192	297	2	.	.	PUNCT
dti-2192	298	1	2020;110(january):154317	2020;110(january):154317	NUM
dti-2192	298	2	.	.	PUNCT
dti-2192	298	3	crossref	crossref	PROPN
dti-2192	298	4	pubmed	pubmed	PROPN
dti-2192	298	5	25	25	NUM
dti-2192	298	6	.	.	PUNCT
dti-2192	299	1	watanabe	watanabe	PROPN
dti-2192	299	2	m	m	PROPN
dti-2192	299	3	,	,	PUNCT
dti-2192	299	4	caruso	caruso	PROPN
dti-2192	299	5	d	d	PROPN
dti-2192	299	6	,	,	PUNCT
dti-2192	299	7	tuccinardi	tuccinardi	PROPN
dti-2192	299	8	d	d	NOUN
dti-2192	299	9	,	,	PUNCT
dti-2192	299	10	et	et	PROPN
dti-2192	299	11	al	al	PROPN
dti-2192	299	12	.	.	PUNCT
dti-2192	300	1	visceral	visceral	ADJ
dti-2192	300	2	fat	fat	NOUN
dti-2192	300	3	shows	show	VERB
dti-2192	300	4	the	the	DET
dti-2192	300	5	strongest	strong	ADJ
dti-2192	300	6	association	association	NOUN
dti-2192	300	7	with	with	ADP
dti-2192	300	8	the	the	DET
dti-2192	300	9	need	need	NOUN
dti-2192	300	10	of	of	ADP
dti-2192	300	11	intensive	intensive	ADJ
dti-2192	300	12	care	care	NOUN
dti-2192	300	13	in	in	ADP
dti-2192	300	14	patients	patient	NOUN
dti-2192	300	15	with	with	ADP
dti-2192	300	16	covid-19	covid-19	PROPN
dti-2192	300	17	.	.	PUNCT
dti-2192	300	18	metabolism	metabolism	NOUN
dti-2192	300	19	.	.	PUNCT
dti-2192	301	1	2020;111:154319	2020;111:154319	NUM
dti-2192	301	2	.	.	PUNCT
dti-2192	302	1	crossref	crossref	PROPN
dti-2192	302	2	pubmed	pubmed	PROPN
dti-2192	302	3	26	26	NUM
dti-2192	302	4	.	.	PUNCT
dti-2192	303	1	yang	yang	PROPN
dti-2192	303	2	y	y	PROPN
dti-2192	303	3	,	,	PUNCT
dti-2192	303	4	ding	ding	NOUN
dti-2192	303	5	l	l	PROPN
dti-2192	303	6	,	,	PUNCT
dti-2192	303	7	zou	zou	PROPN
dti-2192	303	8	x	x	PROPN
dti-2192	303	9	,	,	PUNCT
dti-2192	303	10	et	et	PROPN
dti-2192	303	11	al	al	PROPN
dti-2192	303	12	.	.	PUNCT
dti-2192	304	1	visceral	visceral	ADJ
dti-2192	304	2	adiposity	adiposity	NOUN
dti-2192	304	3	and	and	CCONJ
dti-2192	304	4	high	high	ADJ
dti-2192	304	5	intramuscular	intramuscular	ADJ
dti-2192	304	6	fat	fat	ADJ
dti-2192	304	7	deposition	deposition	NOUN
dti-2192	304	8	independently	independently	ADV
dti-2192	304	9	predict	predict	VERB
dti-2192	304	10	critical	critical	ADJ
dti-2192	304	11	illness	illness	NOUN
dti-2192	304	12	in	in	ADP
dti-2192	304	13	patients	patient	NOUN
dti-2192	304	14	with	with	ADP
dti-2192	304	15	sars	sar	NOUN
dti-2192	304	16	-	-	PUNCT
dti-2192	304	17	cov-2	cov-2	NOUN
dti-2192	304	18	.	.	PUNCT
dti-2192	304	19	obesity	obesity	NOUN
dti-2192	304	20	(	(	PUNCT
dti-2192	304	21	silver	silver	ADJ
dti-2192	304	22	spring	spring	NOUN
dti-2192	304	23	)	)	PUNCT
dti-2192	304	24	.	.	PUNCT
dti-2192	305	1	2020;28(11):2040	2020;28(11):2040	NUM
dti-2192	305	2	-	-	SYM
dti-2192	305	3	2048	2048	NUM
dti-2192	305	4	.	.	PUNCT
dti-2192	306	1	crossref	crossref	PROPN
dti-2192	306	2	pubmed	pubmed	PROPN
dti-2192	306	3	27	27	NUM
dti-2192	306	4	.	.	PUNCT
dti-2192	307	1	shimomura	shimomura	PROPN
dti-2192	307	2	i	i	PROPN
dti-2192	307	3	,	,	PUNCT
dti-2192	307	4	funahashi	funahashi	PROPN
dti-2192	307	5	t	t	PROPN
dti-2192	307	6	,	,	PUNCT
dti-2192	307	7	takahashi	takahashi	PROPN
dti-2192	307	8	m	m	PROPN
dti-2192	307	9	,	,	PUNCT
dti-2192	307	10	et	et	PROPN
dti-2192	307	11	al	al	PROPN
dti-2192	307	12	.	.	PROPN
dti-2192	307	13	enhanced	enhance	VERB
dti-2192	307	14	expression	expression	NOUN
dti-2192	307	15	of	of	ADP
dti-2192	307	16	pai-1	pai-1	NUM
dti-2192	307	17	in	in	ADP
dti-2192	307	18	visceral	visceral	ADJ
dti-2192	307	19	fat	fat	ADJ
dti-2192	307	20	:	:	PUNCT
dti-2192	307	21	possible	possible	ADJ
dti-2192	307	22	contributor	contributor	NOUN
dti-2192	307	23	to	to	PART
dti-2192	307	24	vascular	vascular	VERB
dti-2192	307	25	disease	disease	NOUN
dti-2192	307	26	in	in	ADP
dti-2192	307	27	obesity	obesity	NOUN
dti-2192	307	28	.	.	PUNCT
dti-2192	308	1	nat	nat	PROPN
dti-2192	308	2	med	med	PROPN
dti-2192	308	3	.	.	PUNCT
dti-2192	309	1	1996;2(7):800	1996;2(7):800	NUM
dti-2192	309	2	-	-	SYM
dti-2192	309	3	803	803	NUM
dti-2192	309	4	.	.	PUNCT
dti-2192	310	1	crossref	crossref	PROPN
dti-2192	310	2	pubmed	pubmed	PROPN
dti-2192	310	3	28	28	PROPN
dti-2192	310	4	.	.	PUNCT
dti-2192	311	1	hazeldine	hazeldine	PROPN
dti-2192	311	2	j	j	PROPN
dti-2192	311	3	,	,	PUNCT
dti-2192	311	4	lord	lord	PROPN
dti-2192	311	5	jm	jm	PROPN
dti-2192	311	6	.	.	PROPN
dti-2192	311	7	immunesenescence	immunesenescence	PROPN
dti-2192	311	8	:	:	PUNCT
dti-2192	311	9	a	a	DET
dti-2192	311	10	predisposing	predispose	VERB
dti-2192	311	11	risk	risk	NOUN
dti-2192	311	12	factor	factor	NOUN
dti-2192	311	13	for	for	ADP
dti-2192	311	14	the	the	DET
dti-2192	311	15	development	development	NOUN
dti-2192	311	16	of	of	ADP
dti-2192	311	17	covid-19	covid-19	PROPN
dti-2192	311	18	?	?	PUNCT
dti-2192	311	19	front	front	ADJ
dti-2192	311	20	immunol	immunol	NOUN
dti-2192	311	21	.	.	PUNCT
dti-2192	312	1	2020;11(oct):573662	2020;11(oct):573662	NOUN
dti-2192	312	2	.	.	PUNCT
dti-2192	313	1	crossref	crossref	PROPN
dti-2192	313	2	pubmed	pubmed	PROPN
dti-2192	313	3	29	29	NUM
dti-2192	313	4	.	.	PUNCT
dti-2192	314	1	kumar	kumar	PROPN
dti-2192	314	2	h.	h.	PROPN
dti-2192	314	3	healthy	healthy	ADJ
dti-2192	314	4	immunity	immunity	NOUN
dti-2192	314	5	:	:	PUNCT
dti-2192	314	6	it	it	PRON
dti-2192	314	7	’s	’	VERB
dti-2192	314	8	all	all	ADV
dti-2192	314	9	about	about	ADP
dti-2192	314	10	immune	immune	ADJ
dti-2192	314	11	regulation	regulation	NOUN
dti-2192	314	12	.	.	PUNCT
dti-2192	315	1	int	int	PROPN
dti-2192	315	2	rev	rev	PROPN
dti-2192	315	3	immunol	immunol	NOUN
dti-2192	315	4	.	.	PUNCT
dti-2192	316	1	2020;39(6):245	2020;39(6):245	NUM
dti-2192	316	2	-	-	SYM
dti-2192	316	3	246	246	NUM
dti-2192	316	4	.	.	PUNCT
dti-2192	317	1	crossref	crossref	PROPN
dti-2192	317	2	pubmed	pubmed	PROPN
dti-2192	317	3	30	30	PROPN
dti-2192	317	4	.	.	PUNCT
dti-2192	318	1	popkin	popkin	PROPN
dti-2192	318	2	bm	bm	PROPN
dti-2192	318	3	,	,	PUNCT
dti-2192	318	4	du	du	PROPN
dti-2192	318	5	s	s	PROPN
dti-2192	318	6	,	,	PUNCT
dti-2192	318	7	green	green	PROPN
dti-2192	318	8	wd	wd	PROPN
dti-2192	318	9	,	,	PUNCT
dti-2192	318	10	et	et	PROPN
dti-2192	318	11	al	al	PROPN
dti-2192	318	12	.	.	PUNCT
dti-2192	318	13	individuals	individual	NOUN
dti-2192	318	14	with	with	ADP
dti-2192	318	15	obesity	obesity	NOUN
dti-2192	318	16	and	and	CCONJ
dti-2192	318	17	covid-19	covid-19	PROPN
dti-2192	318	18	:	:	PUNCT
dti-2192	318	19	a	a	DET
dti-2192	318	20	global	global	ADJ
dti-2192	318	21	perspective	perspective	NOUN
dti-2192	318	22	on	on	ADP
dti-2192	318	23	the	the	DET
dti-2192	318	24	epidemiology	epidemiology	NOUN
dti-2192	318	25	and	and	CCONJ
dti-2192	318	26	biological	biological	ADJ
dti-2192	318	27	relationships	relationship	NOUN
dti-2192	318	28	.	.	PUNCT
dti-2192	319	1	obes	obes	PROPN
dti-2192	319	2	rev	rev	VERB
dti-2192	319	3	.	.	PUNCT
dti-2192	319	4	2020;21(11):e13128	2020;21(11):e13128	PROPN
dti-2192	319	5	.	.	PUNCT
dti-2192	320	1	crossref	crossref	PROPN
dti-2192	320	2	pubmed	pubmed	PROPN
dti-2192	320	3	31	31	NUM
dti-2192	320	4	.	.	PUNCT
dti-2192	321	1	ledford	ledford	PROPN
dti-2192	321	2	h.	h.	PROPN
dti-2192	321	3	how	how	SCONJ
dti-2192	321	4	obesity	obesity	NOUN
dti-2192	321	5	could	could	AUX
dti-2192	321	6	create	create	VERB
dti-2192	321	7	problems	problem	NOUN
dti-2192	321	8	for	for	ADP
dti-2192	321	9	a	a	DET
dti-2192	321	10	covid	covid	ADJ
dti-2192	321	11	vaccine	vaccine	NOUN
dti-2192	321	12	.	.	PUNCT
dti-2192	322	1	nature	nature	NOUN
dti-2192	322	2	.	.	PUNCT
dti-2192	323	1	2020;586(7830):488	2020;586(7830):488	NUM
dti-2192	323	2	-	-	SYM
dti-2192	323	3	489	489	NUM
dti-2192	323	4	.	.	PUNCT
dti-2192	324	1	crossref	crossref	PROPN
dti-2192	324	2	pubmed	pubmed	PROPN
dti-2192	324	3	32	32	NUM
dti-2192	324	4	.	.	PUNCT
dti-2192	325	1	esser	esser	PROPN
dti-2192	325	2	n	n	CCONJ
dti-2192	325	3	,	,	PUNCT
dti-2192	325	4	legrand	legrand	PROPN
dti-2192	325	5	-	-	PUNCT
dti-2192	325	6	poels	poels	PROPN
dti-2192	325	7	s	s	PART
dti-2192	325	8	,	,	PUNCT
dti-2192	325	9	piette	piette	PROPN
dti-2192	325	10	j	j	PROPN
dti-2192	325	11	,	,	PUNCT
dti-2192	325	12	scheen	scheen	PROPN
dti-2192	325	13	aj	aj	PROPN
dti-2192	325	14	,	,	PUNCT
dti-2192	325	15	paquot	paquot	ADJ
dti-2192	325	16	n.	n.	NOUN
dti-2192	325	17	inflammation	inflammation	NOUN
dti-2192	325	18	as	as	ADP
dti-2192	325	19	a	a	DET
dti-2192	325	20	link	link	NOUN
dti-2192	325	21	between	between	ADP
dti-2192	325	22	obesity	obesity	NOUN
dti-2192	325	23	,	,	PUNCT
dti-2192	325	24	metabolic	metabolic	NOUN
dti-2192	325	25	syndrome	syndrome	NOUN
dti-2192	325	26	and	and	CCONJ
dti-2192	325	27	type	type	NOUN
dti-2192	325	28	2	2	NUM
dti-2192	325	29	diabetes	diabetes	NOUN
dti-2192	325	30	.	.	PUNCT
dti-2192	326	1	diabetes	diabetes	NOUN
dti-2192	326	2	res	re	VERB
dti-2192	326	3	clin	clin	PROPN
dti-2192	326	4	pract	pract	PROPN
dti-2192	326	5	.	.	PUNCT
dti-2192	327	1	2014;105(2):141	2014;105(2):141	NUM
dti-2192	327	2	-	-	SYM
dti-2192	327	3	150	150	NUM
dti-2192	327	4	.	.	PUNCT
dti-2192	328	1	crossref	crossref	PROPN
dti-2192	328	2	pubmed	pubmed	PROPN
dti-2192	328	3	33	33	NUM
dti-2192	328	4	.	.	PUNCT
dti-2192	329	1	do	do	VERB
dti-2192	329	2	prado	prado	PROPN
dti-2192	329	3	wl	wl	PROPN
dti-2192	329	4	,	,	PUNCT
dti-2192	329	5	lofrano	lofrano	PROPN
dti-2192	329	6	mc	mc	PROPN
dti-2192	329	7	,	,	PUNCT
dti-2192	329	8	oyama	oyama	PROPN
dti-2192	329	9	lm	lm	PROPN
dti-2192	329	10	,	,	PUNCT
dti-2192	329	11	et	et	PROPN
dti-2192	329	12	al	al	PROPN
dti-2192	329	13	.	.	PROPN
dti-2192	329	14	obesity	obesity	NOUN
dti-2192	329	15	and	and	CCONJ
dti-2192	329	16	inflammatory	inflammatory	ADJ
dti-2192	329	17	adipokines	adipokine	NOUN
dti-2192	329	18	:	:	PUNCT
dti-2192	329	19	practical	practical	ADJ
dti-2192	329	20	implications	implication	NOUN
dti-2192	329	21	for	for	ADP
dti-2192	329	22	exercise	exercise	NOUN
dti-2192	329	23	prescription	prescription	NOUN
dti-2192	329	24	.	.	PUNCT
dti-2192	330	1	rev	rev	PROPN
dti-2192	330	2	bras	bras	PROPN
dti-2192	330	3	med	med	PROPN
dti-2192	330	4	esporte	esporte	PROPN
dti-2192	330	5	.	.	PUNCT
dti-2192	331	1	2009;15(5):378	2009;15(5):378	NUM
dti-2192	331	2	-	-	PUNCT
dti-2192	331	3	383	383	NUM
dti-2192	331	4	.	.	PUNCT
dti-2192	332	1	crossref	crossref	PROPN
dti-2192	332	2	34	34	NUM
dti-2192	332	3	.	.	PUNCT
dti-2192	333	1	morais	morais	PROPN
dti-2192	333	2	ah	ah	INTJ
dti-2192	333	3	de	de	PROPN
dti-2192	333	4	a	a	PROPN
dti-2192	333	5	,	,	PUNCT
dti-2192	333	6	aquino	aquino	PROPN
dti-2192	333	7	j	j	PROPN
dti-2192	333	8	de	de	PROPN
dti-2192	333	9	s	s	PROPN
dti-2192	333	10	,	,	PUNCT
dti-2192	333	11	silva	silva	PROPN
dti-2192	333	12	-	-	PUNCT
dti-2192	333	13	maia	maia	PROPN
dti-2192	333	14	jk	jk	PROPN
dti-2192	333	15	da	da	PROPN
dti-2192	333	16	,	,	PUNCT
dti-2192	333	17	vale	vale	ADJ
dti-2192	333	18	sh	sh	PROPN
dti-2192	333	19	de	de	PROPN
dti-2192	333	20	l	l	PROPN
dti-2192	333	21	,	,	PUNCT
dti-2192	333	22	maciel	maciel	PROPN
dti-2192	333	23	bll	bll	PROPN
dti-2192	333	24	,	,	PUNCT
dti-2192	333	25	passos	passos	PROPN
dti-2192	333	26	ts	ts	PROPN
dti-2192	333	27	.	.	PUNCT
dti-2192	333	28	nutritional	nutritional	ADJ
dti-2192	333	29	status	status	NOUN
dti-2192	333	30	,	,	PUNCT
dti-2192	333	31	diet	diet	NOUN
dti-2192	333	32	and	and	CCONJ
dti-2192	333	33	viral	viral	ADJ
dti-2192	333	34	respiratory	respiratory	ADJ
dti-2192	333	35	infections	infection	NOUN
dti-2192	333	36	:	:	PUNCT
dti-2192	333	37	perspectives	perspective	NOUN
dti-2192	333	38	for	for	ADP
dti-2192	333	39	sars	sar	NOUN
dti-2192	333	40	-	-	PUNCT
dti-2192	333	41	cov-2	cov-2	NOUN
dti-2192	333	42	.	.	PUNCT
dti-2192	334	1	br	br	PROPN
dti-2192	334	2	j	j	PROPN
dti-2192	334	3	nutr	nutr	PROPN
dti-2192	334	4	.	.	PROPN
dti-2192	334	5	published	publish	VERB
dti-2192	334	6	online	online	ADJ
dti-2192	334	7	august	august	PROPN
dti-2192	334	8	26	26	NUM
dti-2192	334	9	,	,	PUNCT
dti-2192	334	10	2020:1	2020:1	NUM
dti-2192	334	11	-	-	SYM
dti-2192	334	12	32	32	NUM
dti-2192	334	13	.	.	PUNCT
dti-2192	335	1	crossref	crossref	PROPN
dti-2192	335	2	35	35	NUM
dti-2192	335	3	.	.	PUNCT
dti-2192	336	1	pillaiyar	pillaiyar	PROPN
dti-2192	336	2	t	t	PROPN
dti-2192	336	3	,	,	PUNCT
dti-2192	336	4	meenakshisundaram	meenakshisundaram	PROPN
dti-2192	336	5	s	s	PROPN
dti-2192	336	6	,	,	PUNCT
dti-2192	336	7	manickam	manickam	ADJ
dti-2192	336	8	m.	m.	NOUN
dti-2192	336	9	recent	recent	ADJ
dti-2192	336	10	discovery	discovery	NOUN
dti-2192	336	11	and	and	CCONJ
dti-2192	336	12	development	development	NOUN
dti-2192	336	13	of	of	ADP
dti-2192	336	14	inhibitors	inhibitor	NOUN
dti-2192	336	15	targeting	target	VERB
dti-2192	336	16	coronaviruses	coronaviruse	NOUN
dti-2192	336	17	.	.	PUNCT
dti-2192	337	1	drug	drug	NOUN
dti-2192	337	2	discov	discov	PROPN
dti-2192	337	3	today	today	NOUN
dti-2192	337	4	.	.	PUNCT
dti-2192	338	1	2020;25(4):668	2020;25(4):668	NOUN
dti-2192	338	2	-	-	PUNCT
dti-2192	338	3	688	688	NUM
dti-2192	338	4	.	.	PUNCT
dti-2192	339	1	crossref	crossref	PROPN
dti-2192	339	2	pubmed	pubmed	PROPN
dti-2192	339	3	36	36	NUM
dti-2192	339	4	.	.	PUNCT
dti-2192	340	1	rota	rota	PROPN
dti-2192	340	2	pa	pa	PROPN
dti-2192	340	3	,	,	PUNCT
dti-2192	340	4	oberste	oberste	PROPN
dti-2192	340	5	ms	ms	PROPN
dti-2192	340	6	,	,	PUNCT
dti-2192	340	7	monroe	monroe	PROPN
dti-2192	340	8	ss	ss	PROPN
dti-2192	340	9	,	,	PUNCT
dti-2192	340	10	et	et	PROPN
dti-2192	340	11	al	al	PROPN
dti-2192	340	12	.	.	PUNCT
dti-2192	341	1	characterization	characterization	NOUN
dti-2192	341	2	of	of	ADP
dti-2192	341	3	a	a	DET
dti-2192	341	4	novel	novel	ADJ
dti-2192	341	5	coronavirus	coronavirus	NOUN
dti-2192	341	6	associated	associate	VERB
dti-2192	341	7	with	with	ADP
dti-2192	341	8	severe	severe	ADJ
dti-2192	341	9	acute	acute	ADJ
dti-2192	341	10	respiratory	respiratory	ADJ
dti-2192	341	11	syndrome	syndrome	NOUN
dti-2192	341	12	.	.	PUNCT
dti-2192	342	1	science	science	NOUN
dti-2192	342	2	.	.	PUNCT
dti-2192	343	1	2003;300(5624):1394	2003;300(5624):1394	NUM
dti-2192	343	2	-	-	SYM
dti-2192	343	3	1399	1399	NUM
dti-2192	343	4	.	.	PUNCT
dti-2192	344	1	crossref	crossref	PROPN
dti-2192	344	2	37	37	NUM
dti-2192	344	3	.	.	PUNCT
dti-2192	344	4	yu	yu	PROPN
dti-2192	345	1	r	r	PROPN
dti-2192	345	2	,	,	PUNCT
dti-2192	345	3	chen	chen	PROPN
dti-2192	345	4	l	l	PROPN
dti-2192	345	5	,	,	PUNCT
dti-2192	345	6	lan	lan	PROPN
dti-2192	345	7	r	r	PROPN
dti-2192	345	8	,	,	PUNCT
dti-2192	345	9	shen	shen	NOUN
dti-2192	345	10	r	r	NOUN
dti-2192	345	11	,	,	PUNCT
dti-2192	345	12	li	li	PROPN
dti-2192	346	1	p.	p.	PROPN
dti-2192	346	2	computational	computational	ADJ
dti-2192	346	3	screening	screening	NOUN
dti-2192	346	4	of	of	ADP
dti-2192	346	5	antagonists	antagonist	NOUN
dti-2192	346	6	against	against	ADP
dti-2192	346	7	the	the	DET
dti-2192	346	8	sars	sar	NOUN
dti-2192	346	9	-	-	PUNCT
dti-2192	346	10	cov-2	cov-2	PART
dti-2192	346	11	(	(	PUNCT
dti-2192	346	12	covid-19	covid-19	PROPN
dti-2192	346	13	)	)	PUNCT
dti-2192	346	14	coronavirus	coronavirus	NOUN
dti-2192	346	15	by	by	ADP
dti-2192	346	16	molecular	molecular	ADJ
dti-2192	346	17	docking	docking	NOUN
dti-2192	346	18	.	.	PUNCT
dti-2192	347	1	int	int	NOUN
dti-2192	347	2	j	j	PROPN
dti-2192	347	3	antimicrob	antimicrob	PROPN
dti-2192	347	4	agents	agent	NOUN
dti-2192	347	5	.	.	PUNCT
dti-2192	348	1	2020;56(2):106012	2020;56(2):106012	NUM
dti-2192	348	2	.	.	PUNCT
dti-2192	349	1	crossref	crossref	PROPN
dti-2192	349	2	pubmed	pubmed	PROPN
dti-2192	349	3	38	38	NUM
dti-2192	349	4	.	.	PUNCT
dti-2192	350	1	forni	forni	PROPN
dti-2192	350	2	d	d	PROPN
dti-2192	350	3	,	,	PUNCT
dti-2192	350	4	cagliani	cagliani	PROPN
dti-2192	350	5	r	r	NOUN
dti-2192	350	6	,	,	PUNCT
dti-2192	350	7	clerici	clerici	NOUN
dti-2192	350	8	m	m	PROPN
dti-2192	350	9	,	,	PUNCT
dti-2192	350	10	sironi	sironi	PROPN
dti-2192	350	11	m.	m.	NOUN
dti-2192	350	12	molecular	molecular	ADJ
dti-2192	350	13	evolution	evolution	NOUN
dti-2192	350	14	of	of	ADP
dti-2192	350	15	human	human	ADJ
dti-2192	350	16	coronavirus	coronavirus	NOUN
dti-2192	350	17	genomes	genome	NOUN
dti-2192	350	18	.	.	PUNCT
dti-2192	351	1	trends	trend	NOUN
dti-2192	351	2	microbiol	microbiol	PROPN
dti-2192	351	3	.	.	PUNCT
dti-2192	352	1	2017;25(1	2017;25(1	NUM
dti-2192	352	2	):	):	PUNCT
dti-2192	352	3	35	35	NUM
dti-2192	352	4	-	-	SYM
dti-2192	352	5	48	48	NUM
dti-2192	352	6	.	.	PUNCT
dti-2192	353	1	crossref	crossref	PROPN
dti-2192	353	2	pubmed	pubmed	PROPN
dti-2192	353	3	39	39	NUM
dti-2192	353	4	.	.	PUNCT
dti-2192	354	1	liu	liu	PROPN
dti-2192	354	2	y	y	PROPN
dti-2192	354	3	,	,	PUNCT
dti-2192	354	4	liang	liang	PROPN
dti-2192	354	5	c	c	PROPN
dti-2192	354	6	,	,	PUNCT
dti-2192	354	7	xin	xin	PROPN
dti-2192	354	8	l	l	PROPN
dti-2192	354	9	,	,	PUNCT
dti-2192	354	10	et	et	PROPN
dti-2192	354	11	al	al	PROPN
dti-2192	354	12	.	.	PUNCT
dti-2192	355	1	the	the	DET
dti-2192	355	2	development	development	NOUN
dti-2192	355	3	of	of	ADP
dti-2192	355	4	coronavirus	coronavirus	NOUN
dti-2192	355	5	3clike	3clike	NUM
dti-2192	355	6	protease	protease	NOUN
dti-2192	355	7	(	(	PUNCT
dti-2192	355	8	3clpro	3clpro	NUM
dti-2192	355	9	)	)	PUNCT
dti-2192	355	10	inhibitors	inhibitor	NOUN
dti-2192	355	11	from	from	ADP
dti-2192	355	12	2010	2010	NUM
dti-2192	355	13	to	to	ADP
dti-2192	355	14	2020	2020	NUM
dti-2192	355	15	.	.	PUNCT
dti-2192	356	1	eur	eur	PROPN
dti-2192	356	2	j	j	PROPN
dti-2192	356	3	med	med	PROPN
dti-2192	356	4	chem	chem	NOUN
dti-2192	356	5	.	.	PUNCT
dti-2192	357	1	2020;206:112711	2020;206:112711	X
dti-2192	357	2	.	.	PUNCT
dti-2192	358	1	crossref	crossref	PROPN
dti-2192	358	2	pubmed	pubmed	PROPN
dti-2192	358	3	40	40	NUM
dti-2192	358	4	.	.	PUNCT
dti-2192	359	1	hoffmann	hoffmann	PROPN
dti-2192	359	2	m	m	PROPN
dti-2192	359	3	,	,	PUNCT
dti-2192	359	4	kleine	kleine	PROPN
dti-2192	359	5	-	-	PUNCT
dti-2192	359	6	weber	weber	PROPN
dti-2192	359	7	h	h	PROPN
dti-2192	359	8	,	,	PUNCT
dti-2192	359	9	schroeder	schroeder	PROPN
dti-2192	359	10	s	s	PROPN
dti-2192	359	11	,	,	PUNCT
dti-2192	359	12	et	et	PROPN
dti-2192	359	13	al	al	PROPN
dti-2192	359	14	.	.	PUNCT
dti-2192	360	1	sars	sars	PROPN
dti-2192	360	2	-	-	PUNCT
dti-2192	360	3	cov-2	cov-2	PART
dti-2192	360	4	cell	cell	NOUN
dti-2192	360	5	entry	entry	NOUN
dti-2192	360	6	depends	depend	VERB
dti-2192	360	7	on	on	ADP
dti-2192	360	8	ace2	ace2	NOUN
dti-2192	360	9	and	and	CCONJ
dti-2192	360	10	tmprss2	tmprss2	ADV
dti-2192	360	11	and	and	CCONJ
dti-2192	360	12	is	be	AUX
dti-2192	360	13	blocked	block	VERB
dti-2192	360	14	by	by	ADP
dti-2192	360	15	a	a	DET
dti-2192	360	16	clinically	clinically	ADV
dti-2192	360	17	proven	prove	VERB
dti-2192	360	18	protease	protease	NOUN
dti-2192	360	19	inhibitor	inhibitor	NOUN
dti-2192	360	20	.	.	PUNCT
dti-2192	361	1	cell	cell	NOUN
dti-2192	361	2	.	.	PUNCT
dti-2192	362	1	published	publish	VERB
dti-2192	362	2	online	online	ADJ
dti-2192	362	3	2020:1	2020:1	NUM
dti-2192	362	4	-	-	SYM
dti-2192	362	5	10	10	NUM
dti-2192	362	6	.	.	PUNCT
dti-2192	363	1	crossref	crossref	PROPN
dti-2192	363	2	41	41	NUM
dti-2192	363	3	.	.	PUNCT
dti-2192	364	1	xu	xu	PROPN
dti-2192	364	2	xw	xw	PROPN
dti-2192	364	3	,	,	PUNCT
dti-2192	364	4	wu	wu	PROPN
dti-2192	364	5	xx	xx	PROPN
dti-2192	364	6	,	,	PUNCT
dti-2192	364	7	jiang	jiang	PROPN
dti-2192	364	8	xg	xg	PROPN
dti-2192	364	9	,	,	PUNCT
dti-2192	364	10	et	et	PROPN
dti-2192	364	11	al	al	PROPN
dti-2192	364	12	.	.	PUNCT
dti-2192	365	1	clinical	clinical	ADJ
dti-2192	365	2	findings	finding	NOUN
dti-2192	365	3	in	in	ADP
dti-2192	365	4	a	a	DET
dti-2192	365	5	group	group	NOUN
dti-2192	365	6	of	of	ADP
dti-2192	365	7	patients	patient	NOUN
dti-2192	365	8	infected	infect	VERB
dti-2192	365	9	with	with	ADP
dti-2192	365	10	the	the	DET
dti-2192	365	11	2019	2019	NUM
dti-2192	365	12	novel	novel	ADJ
dti-2192	365	13	coronavirus	coronavirus	NOUN
dti-2192	365	14	(	(	PUNCT
dti-2192	365	15	sars	sar	NOUN
dti-2192	365	16	-	-	PUNCT
dti-2192	365	17	cov-2	cov-2	NOUN
dti-2192	365	18	)	)	PUNCT
dti-2192	365	19	outside	outside	ADV
dti-2192	365	20	of	of	ADP
dti-2192	365	21	wuhan	wuhan	PROPN
dti-2192	365	22	,	,	PUNCT
dti-2192	365	23	china	china	PROPN
dti-2192	365	24	:	:	PUNCT
dti-2192	365	25	retrospective	retrospective	ADJ
dti-2192	365	26	case	case	NOUN
dti-2192	365	27	series	series	NOUN
dti-2192	365	28	.	.	PUNCT
dti-2192	366	1	bmj	bmj	PROPN
dti-2192	366	2	.	.	PUNCT
dti-2192	367	1	2020;368(jan):m606	2020;368(jan):m606	PROPN
dti-2192	367	2	.	.	PUNCT
dti-2192	368	1	crossref	crossref	PROPN
dti-2192	368	2	pubmed	pubmed	PROPN
dti-2192	368	3	42	42	NUM
dti-2192	368	4	.	.	PUNCT
dti-2192	369	1	simões	simões	PROPN
dti-2192	369	2	e	e	PROPN
dti-2192	369	3	silva	silva	PROPN
dti-2192	369	4	ac	ac	PROPN
dti-2192	369	5	,	,	PUNCT
dti-2192	369	6	silveira	silveira	PROPN
dti-2192	369	7	kd	kd	PROPN
dti-2192	369	8	,	,	PUNCT
dti-2192	369	9	ferreira	ferreira	PROPN
dti-2192	369	10	aj	aj	PROPN
dti-2192	369	11	,	,	PUNCT
dti-2192	369	12	teixeira	teixeira	PROPN
dti-2192	369	13	mm	mm	PROPN
dti-2192	369	14	.	.	PUNCT
dti-2192	369	15	ace2	ace2	PROPN
dti-2192	369	16	,	,	PUNCT
dti-2192	369	17	angiotensin-(1	angiotensin-(1	PROPN
dti-2192	369	18	-	-	PUNCT
dti-2192	369	19	7	7	NUM
dti-2192	369	20	)	)	PUNCT
dti-2192	369	21	and	and	CCONJ
dti-2192	369	22	mas	mas	PROPN
dti-2192	369	23	receptor	receptor	NOUN
dti-2192	369	24	axis	axis	NOUN
dti-2192	369	25	in	in	ADP
dti-2192	369	26	inflammation	inflammation	NOUN
dti-2192	369	27	and	and	CCONJ
dti-2192	369	28	fibrosis	fibrosis	NOUN
dti-2192	369	29	.	.	PUNCT
dti-2192	370	1	br	br	PROPN
dti-2192	370	2	j	j	PROPN
dti-2192	370	3	pharmacol	pharmacol	PROPN
dti-2192	370	4	.	.	PUNCT
dti-2192	371	1	2013;169(3):477	2013;169(3):477	NUM
dti-2192	371	2	-	-	SYM
dti-2192	371	3	492	492	NUM
dti-2192	371	4	.	.	PUNCT
dti-2192	372	1	crossref	crossref	PROPN
dti-2192	372	2	pubmed	pubmed	PROPN
dti-2192	372	3	43	43	NUM
dti-2192	372	4	.	.	PUNCT
dti-2192	373	1	santos	santos	PROPN
dti-2192	373	2	ras	ras	PROPN
dti-2192	373	3	,	,	PUNCT
dti-2192	373	4	ferreira	ferreira	PROPN
dti-2192	373	5	aj	aj	PROPN
dti-2192	373	6	,	,	PUNCT
dti-2192	373	7	simões	simões	ADJ
dti-2192	373	8	e	e	NOUN
dti-2192	373	9	,	,	PUNCT
dti-2192	373	10	silva	silva	PROPN
dti-2192	373	11	ac	ac	PROPN
dti-2192	373	12	,	,	PUNCT
dti-2192	373	13	silva	silva	PROPN
dti-2192	373	14	ac	ac	PROPN
dti-2192	373	15	.	.	PUNCT
dti-2192	374	1	recent	recent	ADJ
dti-2192	374	2	advances	advance	NOUN
dti-2192	374	3	in	in	ADP
dti-2192	374	4	the	the	DET
dti-2192	374	5	angiotensin	angiotensin	NOUN
dti-2192	374	6	-	-	PUNCT
dti-2192	374	7	converting	convert	VERB
dti-2192	374	8	enzyme	enzyme	NOUN
dti-2192	374	9	2	2	NUM
dti-2192	374	10	-	-	PUNCT
dti-2192	374	11	angiotensin	angiotensin	NOUN
dti-2192	374	12	(	(	PUNCT
dti-2192	374	13	1	1	NUM
dti-2192	374	14	-	-	PUNCT
dti-2192	374	15	7)-mas	7)-mas	NUM
dti-2192	374	16	axis	axis	NOUN
dti-2192	374	17	.	.	PUNCT
dti-2192	375	1	exp	exp	NOUN
dti-2192	375	2	physiol	physiol	NOUN
dti-2192	375	3	.	.	PUNCT
dti-2192	376	1	2008;93(5):519	2008;93(5):519	NUM
dti-2192	376	2	-	-	SYM
dti-2192	376	3	527	527	NUM
dti-2192	376	4	.	.	PUNCT
dti-2192	377	1	crossref	crossref	PROPN
dti-2192	377	2	pubmed	pubmed	PROPN
dti-2192	377	3	44	44	NUM
dti-2192	377	4	.	.	PUNCT
dti-2192	378	1	ferreira	ferreira	PROPN
dti-2192	378	2	aj	aj	PROPN
dti-2192	378	3	,	,	PUNCT
dti-2192	378	4	santos	santos	PROPN
dti-2192	378	5	ras	ras	PROPN
dti-2192	378	6	,	,	PUNCT
dti-2192	378	7	bradford	bradford	PROPN
dti-2192	378	8	cn	cn	PROPN
dti-2192	378	9	,	,	PUNCT
dti-2192	378	10	et	et	PROPN
dti-2192	378	11	al	al	PROPN
dti-2192	378	12	.	.	PUNCT
dti-2192	379	1	therapeutic	therapeutic	ADJ
dti-2192	379	2	implications	implication	NOUN
dti-2192	379	3	of	of	ADP
dti-2192	379	4	the	the	DET
dti-2192	379	5	vasoprotective	vasoprotective	ADJ
dti-2192	379	6	axis	axis	NOUN
dti-2192	379	7	of	of	ADP
dti-2192	379	8	the	the	DET
dti-2192	379	9	renin	renin	ADJ
dti-2192	379	10	-	-	PUNCT
dti-2192	379	11	angiotensin	angiotensin	NOUN
dti-2192	379	12	system	system	NOUN
dti-2192	379	13	in	in	ADP
dti-2192	379	14	cardiovascular	cardiovascular	ADJ
dti-2192	379	15	diseases	disease	NOUN
dti-2192	379	16	.	.	PUNCT
dti-2192	380	1	hypertension	hypertension	NOUN
dti-2192	380	2	.	.	PUNCT
dti-2192	381	1	2010;55(2):207213	2010;55(2):207213	NUM
dti-2192	381	2	.	.	PUNCT
dti-2192	382	1	crossref	crossref	PROPN
dti-2192	382	2	pubmed	pubmed	PROPN
dti-2192	382	3	45	45	NUM
dti-2192	382	4	.	.	PUNCT
dti-2192	383	1	santos	santos	PROPN
dti-2192	383	2	pcjl	pcjl	PROPN
dti-2192	383	3	,	,	PUNCT
dti-2192	383	4	krieger	krieger	PROPN
dti-2192	383	5	je	je	PROPN
dti-2192	383	6	,	,	PUNCT
dti-2192	383	7	pereira	pereira	PROPN
dti-2192	383	8	ac	ac	PROPN
dti-2192	383	9	.	.	PUNCT
dti-2192	384	1	renin	renin	ADJ
dti-2192	384	2	-	-	PUNCT
dti-2192	384	3	angiotensin	angiotensin	NOUN
dti-2192	384	4	system	system	NOUN
dti-2192	384	5	,	,	PUNCT
dti-2192	384	6	hypertension	hypertension	NOUN
dti-2192	384	7	,	,	PUNCT
dti-2192	384	8	and	and	CCONJ
dti-2192	384	9	chronic	chronic	ADJ
dti-2192	384	10	kidney	kidney	NOUN
dti-2192	384	11	disease	disease	NOUN
dti-2192	384	12	:	:	PUNCT
dti-2192	384	13	pharmacogenetic	pharmacogenetic	ADJ
dti-2192	384	14	implications	implication	NOUN
dti-2192	384	15	.	.	PUNCT
dti-2192	385	1	j	j	PROPN
dti-2192	385	2	pharmacol	pharmacol	PROPN
dti-2192	385	3	sci	sci	PROPN
dti-2192	385	4	.	.	PUNCT
dti-2192	385	5	2012;120(2):77	2012;120(2):77	PROPN
dti-2192	385	6	-	-	PUNCT
dti-2192	385	7	88	88	NUM
dti-2192	385	8	.	.	PUNCT
dti-2192	386	1	crossref	crossref	PROPN
dti-2192	386	2	pubmed	pubmed	PROPN
dti-2192	386	3	46	46	NUM
dti-2192	386	4	.	.	PUNCT
dti-2192	387	1	shinozaki	shinozaki	PROPN
dti-2192	387	2	k	k	PROPN
dti-2192	387	3	,	,	PUNCT
dti-2192	387	4	ayajiki	ayajiki	PROPN
dti-2192	387	5	k	k	PROPN
dti-2192	387	6	,	,	PUNCT
dti-2192	387	7	nishio	nishio	PROPN
dti-2192	387	8	y	y	PROPN
dti-2192	387	9	,	,	PUNCT
dti-2192	387	10	sugaya	sugaya	PROPN
dti-2192	387	11	t	t	PROPN
dti-2192	387	12	,	,	PUNCT
dti-2192	387	13	kashiwagi	kashiwagi	PROPN
dti-2192	387	14	a	a	PROPN
dti-2192	387	15	,	,	PUNCT
dti-2192	387	16	okamura	okamura	PRON
dti-2192	387	17	t.	t.	NOUN
dti-2192	387	18	evidence	evidence	NOUN
dti-2192	387	19	for	for	ADP
dti-2192	387	20	a	a	DET
dti-2192	387	21	causal	causal	ADJ
dti-2192	387	22	role	role	NOUN
dti-2192	387	23	of	of	ADP
dti-2192	387	24	the	the	DET
dti-2192	387	25	renin	renin	ADJ
dti-2192	387	26	-	-	PUNCT
dti-2192	387	27	angiotensin	angiotensin	NOUN
dti-2192	387	28	system	system	NOUN
dti-2192	387	29	in	in	ADP
dti-2192	387	30	vascular	vascular	ADJ
dti-2192	387	31	dysfunction	dysfunction	NOUN
dti-2192	387	32	associated	associate	VERB
dti-2192	387	33	with	with	ADP
dti-2192	387	34	insulin	insulin	NOUN
dti-2192	387	35	resistance	resistance	NOUN
dti-2192	387	36	.	.	PUNCT
dti-2192	388	1	hypertension	hypertension	NOUN
dti-2192	388	2	.	.	PUNCT
dti-2192	389	1	2004;43(2	2004;43(2	NUM
dti-2192	389	2	i):255	i):255	NOUN
dti-2192	389	3	-	-	SYM
dti-2192	389	4	262	262	NUM
dti-2192	389	5	.	.	PUNCT
dti-2192	390	1	crossref	crossref	PROPN
dti-2192	390	2	47	47	NUM
dti-2192	390	3	.	.	PUNCT
dti-2192	391	1	engeli	engeli	PROPN
dti-2192	391	2	s	s	PROPN
dti-2192	391	3	,	,	PUNCT
dti-2192	391	4	negrel	negrel	NOUN
dti-2192	391	5	r	r	NOUN
dti-2192	391	6	,	,	PUNCT
dti-2192	391	7	sharma	sharma	PROPN
dti-2192	391	8	am	be	AUX
dti-2192	391	9	.	.	PUNCT
dti-2192	391	10	physiology	physiology	NOUN
dti-2192	391	11	and	and	CCONJ
dti-2192	391	12	pathophysiology	pathophysiology	NOUN
dti-2192	391	13	of	of	ADP
dti-2192	391	14	the	the	DET
dti-2192	391	15	adipose	adipose	ADJ
dti-2192	391	16	tissue	tissue	NOUN
dti-2192	391	17	renin	renin	ADJ
dti-2192	391	18	-	-	PUNCT
dti-2192	391	19	angiotensin	angiotensin	NOUN
dti-2192	391	20	system	system	NOUN
dti-2192	391	21	.	.	PUNCT
dti-2192	392	1	hypertension	hypertension	NOUN
dti-2192	392	2	.	.	PUNCT
dti-2192	393	1	2000;35(6):1270	2000;35(6):1270	NUM
dti-2192	393	2	-	-	PUNCT
dti-2192	393	3	1277	1277	NUM
dti-2192	393	4	.	.	PUNCT
dti-2192	394	1	crossref	crossref	PROPN
dti-2192	394	2	pubmed	pubmed	PROPN
dti-2192	394	3	48	48	NUM
dti-2192	394	4	.	.	PUNCT
dti-2192	395	1	liu	liu	PROPN
dti-2192	395	2	j	j	PROPN
dti-2192	395	3	,	,	PUNCT
dti-2192	395	4	cao	cao	PROPN
dti-2192	395	5	r	r	PROPN
dti-2192	395	6	,	,	PUNCT
dti-2192	395	7	xu	xu	PROPN
dti-2192	395	8	m	m	PROPN
dti-2192	395	9	,	,	PUNCT
dti-2192	395	10	et	et	PROPN
dti-2192	395	11	al	al	PROPN
dti-2192	395	12	.	.	PROPN
dti-2192	395	13	hydroxychloroquine	hydroxychloroquine	PROPN
dti-2192	395	14	,	,	PUNCT
dti-2192	395	15	a	a	DET
dti-2192	395	16	less	less	ADV
dti-2192	395	17	toxic	toxic	ADJ
dti-2192	395	18	derivative	derivative	NOUN
dti-2192	395	19	of	of	ADP
dti-2192	395	20	chloroquine	chloroquine	NOUN
dti-2192	395	21	,	,	PUNCT
dti-2192	395	22	is	be	AUX
dti-2192	395	23	effective	effective	ADJ
dti-2192	395	24	in	in	ADP
dti-2192	395	25	inhibiting	inhibit	VERB
dti-2192	395	26	sars	sar	NOUN
dti-2192	395	27	-	-	PUNCT
dti-2192	395	28	cov-2	cov-2	NOUN
dti-2192	395	29	infection	infection	NOUN
dti-2192	395	30	in	in	ADP
dti-2192	395	31	vitro	vitro	X
dti-2192	395	32	.	.	PUNCT
dti-2192	396	1	cell	cell	NOUN
dti-2192	396	2	discov	discov	NOUN
dti-2192	396	3	.	.	PUNCT
dti-2192	397	1	2020;6(1):16	2020;6(1):16	X
dti-2192	397	2	.	.	PUNCT
dti-2192	397	3	crossref	crossref	PROPN
dti-2192	397	4	pubmed	pubmed	PROPN
dti-2192	397	5	49	49	NUM
dti-2192	397	6	.	.	PUNCT
dti-2192	398	1	roca	roca	PROPN
dti-2192	398	2	-	-	PUNCT
dti-2192	398	3	ho	ho	PROPN
dti-2192	398	4	h	h	PROPN
dti-2192	398	5	,	,	PUNCT
dti-2192	398	6	riera	riera	PROPN
dti-2192	398	7	m	m	PROPN
dti-2192	398	8	,	,	PUNCT
dti-2192	398	9	palau	palau	PROPN
dti-2192	398	10	v	v	ADP
dti-2192	398	11	,	,	PUNCT
dti-2192	398	12	pascual	pascual	PROPN
dti-2192	398	13	j	j	PROPN
dti-2192	398	14	,	,	PUNCT
dti-2192	398	15	soler	soler	PROPN
dti-2192	398	16	mj	mj	PROPN
dti-2192	398	17	.	.	PROPN
dti-2192	398	18	characterization	characterization	NOUN
dti-2192	398	19	of	of	ADP
dti-2192	398	20	ace	ace	NOUN
dti-2192	398	21	and	and	CCONJ
dti-2192	398	22	ace2	ace2	NOUN
dti-2192	398	23	expression	expression	NOUN
dti-2192	398	24	within	within	ADP
dti-2192	398	25	different	different	ADJ
dti-2192	398	26	organs	organ	NOUN
dti-2192	398	27	of	of	ADP
dti-2192	398	28	the	the	DET
dti-2192	398	29	nod	nod	PROPN
dti-2192	398	30	mouse	mouse	NOUN
dti-2192	398	31	.	.	PUNCT
dti-2192	399	1	int	int	PROPN
dti-2192	399	2	j	j	PROPN
dti-2192	399	3	mol	mol	ADP
dti-2192	399	4	sci	sci	PROPN
dti-2192	399	5	.	.	PUNCT
dti-2192	399	6	2017;18(3):e563	2017;18(3):e563	NOUN
dti-2192	399	7	.	.	PUNCT
dti-2192	400	1	crossref	crossref	PROPN
dti-2192	400	2	pubmed	pubmed	PROPN
dti-2192	400	3	50	50	NUM
dti-2192	400	4	.	.	PUNCT
dti-2192	401	1	mehta	mehta	PROPN
dti-2192	401	2	p	p	PROPN
dti-2192	401	3	,	,	PUNCT
dti-2192	401	4	mcauley	mcauley	PROPN
dti-2192	401	5	df	df	PROPN
dti-2192	401	6	,	,	PUNCT
dti-2192	401	7	brown	brown	PROPN
dti-2192	401	8	m	m	PROPN
dti-2192	401	9	,	,	PUNCT
dti-2192	401	10	sanchez	sanchez	PROPN
dti-2192	401	11	e	e	NOUN
dti-2192	401	12	,	,	PUNCT
dti-2192	401	13	tattersall	tattersall	NOUN
dti-2192	401	14	rs	rs	NOUN
dti-2192	401	15	,	,	PUNCT
dti-2192	401	16	manson	manson	PROPN
dti-2192	401	17	jj	jj	PROPN
dti-2192	401	18	.	.	PROPN
dti-2192	401	19	hlh	hlh	PROPN
dti-2192	401	20	across	across	ADP
dti-2192	401	21	speciality	speciality	NOUN
dti-2192	401	22	collaboration	collaboration	NOUN
dti-2192	401	23	,	,	PUNCT
dti-2192	401	24	uk	uk	PROPN
dti-2192	401	25	.	.	PUNCT
dti-2192	401	26	covid-19	covid-19	PROPN
dti-2192	401	27	:	:	PUNCT
dti-2192	401	28	consider	consider	VERB
dti-2192	401	29	cytokine	cytokine	ADJ
dti-2192	401	30	storm	storm	NOUN
dti-2192	401	31	syndromes	syndrome	NOUN
dti-2192	401	32	and	and	CCONJ
dti-2192	401	33	immunosuppression	immunosuppression	NOUN
dti-2192	401	34	.	.	PUNCT
dti-2192	402	1	lancet	lancet	PROPN
dti-2192	402	2	.	.	PUNCT
dti-2192	403	1	2020;395(10229):1033	2020;395(10229):1033	NUM
dti-2192	403	2	-	-	SYM
dti-2192	403	3	1034	1034	NUM
dti-2192	403	4	.	.	PUNCT
dti-2192	404	1	crossref	crossref	PROPN
dti-2192	404	2	pubmed	pubmed	PROPN
dti-2192	404	3	51	51	NUM
dti-2192	404	4	.	.	PUNCT
dti-2192	405	1	al	al	PROPN
dti-2192	405	2	heialy	heialy	PROPN
dti-2192	405	3	s	s	PART
dti-2192	405	4	,	,	PUNCT
dti-2192	405	5	hachim	hachim	PRON
dti-2192	405	6	my	my	PRON
dti-2192	405	7	,	,	PUNCT
dti-2192	405	8	senok	senok	PROPN
dti-2192	405	9	a	a	NOUN
dti-2192	405	10	,	,	PUNCT
dti-2192	405	11	et	et	PROPN
dti-2192	405	12	al	al	PROPN
dti-2192	405	13	.	.	PUNCT
dti-2192	406	1	regulation	regulation	NOUN
dti-2192	406	2	of	of	ADP
dti-2192	406	3	angiotensin	angiotensin	NOUN
dti-2192	406	4	converting	convert	VERB
dti-2192	406	5	enzyme	enzyme	NOUN
dti-2192	406	6	2	2	NUM
dti-2192	406	7	(	(	PUNCT
dti-2192	406	8	ace2	ace2	PROPN
dti-2192	406	9	)	)	PUNCT
dti-2192	406	10	in	in	ADP
dti-2192	406	11	obesity	obesity	NOUN
dti-2192	406	12	:	:	PUNCT
dti-2192	406	13	implications	implication	NOUN
dti-2192	406	14	for	for	ADP
dti-2192	406	15	covid-19	covid-19	PROPN
dti-2192	406	16	.	.	PUNCT
dti-2192	406	17	biorxiv	biorxiv	PROPN
dti-2192	406	18	.	.	PUNCT
dti-2192	407	1	2020;2:2020.04.17.046938	2020;2:2020.04.17.046938	NOUN
dti-2192	407	2	.	.	PUNCT
dti-2192	408	1	crossref	crossref	PROPN
dti-2192	408	2	52	52	NUM
dti-2192	408	3	.	.	PUNCT
dti-2192	409	1	sanders	sanders	PROPN
dti-2192	409	2	jm	jm	PROPN
dti-2192	409	3	,	,	PUNCT
dti-2192	409	4	monogue	monogue	NOUN
dti-2192	409	5	ml	ml	NOUN
dti-2192	409	6	,	,	PUNCT
dti-2192	409	7	jodlowski	jodlowski	PROPN
dti-2192	409	8	tz	tz	PROPN
dti-2192	409	9	,	,	PUNCT
dti-2192	409	10	cutrell	cutrell	VERB
dti-2192	409	11	jb	jb	PROPN
dti-2192	409	12	.	.	PUNCT
dti-2192	410	1	pharmacologic	pharmacologic	ADJ
dti-2192	410	2	treatments	treatment	NOUN
dti-2192	410	3	for	for	ADP
dti-2192	410	4	coronavirus	coronavirus	NOUN
dti-2192	410	5	disease	disease	NOUN
dti-2192	410	6	2019	2019	NUM
dti-2192	410	7	(	(	PUNCT
dti-2192	410	8	covid-19	covid-19	PROPN
dti-2192	410	9	):	):	PUNCT
dti-2192	410	10	a	a	DET
dti-2192	410	11	review	review	NOUN
dti-2192	410	12	.	.	PUNCT
dti-2192	411	1	jama	jama	PROPN
dti-2192	411	2	.	.	PUNCT
dti-2192	412	1	2020;323(18):1824	2020;323(18):1824	NUM
dti-2192	412	2	-	-	SYM
dti-2192	412	3	1836	1836	NUM
dti-2192	412	4	.	.	PUNCT
dti-2192	413	1	crossref	crossref	PROPN
dti-2192	413	2	pubmed	pubmed	PROPN
dti-2192	413	3	53	53	NUM
dti-2192	413	4	.	.	PUNCT
dti-2192	414	1	mamber	mamber	PROPN
dti-2192	414	2	s	s	PROPN
dti-2192	414	3	,	,	PUNCT
dti-2192	414	4	krakowka	krakowka	NOUN
dti-2192	414	5	s	s	PROPN
dti-2192	414	6	,	,	PUNCT
dti-2192	414	7	osborn	osborn	PROPN
dti-2192	414	8	j	j	PROPN
dti-2192	414	9	,	,	PUNCT
dti-2192	414	10	et	et	PROPN
dti-2192	414	11	al	al	PROPN
dti-2192	414	12	.	.	PROPN
dti-2192	415	1	could	could	AUX
dti-2192	415	2	unconventional	unconventional	ADJ
dti-2192	415	3	immunomodulatory	immunomodulatory	ADJ
dti-2192	415	4	agents	agent	NOUN
dti-2192	415	5	help	help	AUX
dti-2192	415	6	alleviate	alleviate	VERB
dti-2192	415	7	covid-19	covid-19	PROPN
dti-2192	415	8	symptoms	symptom	NOUN
dti-2192	415	9	and	and	CCONJ
dti-2192	415	10	severity	severity	NOUN
dti-2192	415	11	?	?	PUNCT
dti-2192	416	1	preprints	preprint	NOUN
dti-2192	416	2	.	.	PUNCT
dti-2192	417	1	2020;(april	2020;(april	NUM
dti-2192	417	2	)	)	PUNCT
dti-2192	417	3	.	.	PUNCT
dti-2192	418	1	crossref	crossref	PROPN
dti-2192	418	2	54	54	NUM
dti-2192	418	3	.	.	PUNCT
dti-2192	419	1	he	he	PRON
dti-2192	419	2	j	j	PROPN
dti-2192	419	3	,	,	PUNCT
dti-2192	419	4	hu	hu	PROPN
dti-2192	420	1	l	l	PROPN
dti-2192	420	2	,	,	PUNCT
dti-2192	420	3	huang	huang	PROPN
dti-2192	420	4	x	x	PROPN
dti-2192	420	5	,	,	PUNCT
dti-2192	420	6	et	et	PROPN
dti-2192	420	7	al	al	PROPN
dti-2192	420	8	.	.	PROPN
dti-2192	420	9	potential	potential	NOUN
dti-2192	420	10	of	of	ADP
dti-2192	420	11	coronavirus	coronavirus	NOUN
dti-2192	420	12	3c	3c	NUM
dti-2192	420	13	-	-	PUNCT
dti-2192	420	14	like	like	ADJ
dti-2192	420	15	protease	protease	NOUN
dti-2192	420	16	inhibitors	inhibitor	NOUN
dti-2192	420	17	for	for	ADP
dti-2192	420	18	the	the	DET
dti-2192	420	19	development	development	NOUN
dti-2192	420	20	of	of	ADP
dti-2192	420	21	new	new	ADJ
dti-2192	420	22	anti	anti	ADJ
dti-2192	420	23	-	-	ADJ
dti-2192	420	24	sars	sar	NOUN
dti-2192	420	25	-	-	PUNCT
dti-2192	420	26	cov-2	cov-2	NOUN
dti-2192	420	27	https://doi.org/10.1093/heapro/dax026	https://doi.org/10.1093/heapro/dax026	PROPN
dti-2192	420	28	https://www.ncbi.nlm.nih.gov/pubmed/28541498	https://www.ncbi.nlm.nih.gov/pubmed/28541498	NUM
dti-2192	420	29	https://doi.org/10.1126/science.abb5793	https://doi.org/10.1126/science.abb5793	PROPN
dti-2192	420	30	https://doi.org/10.3389/fmicb.2017.01157	https://doi.org/10.3389/fmicb.2017.01157	PROPN
dti-2192	420	31	https://www.ncbi.nlm.nih.gov/pubmed/28690599	https://www.ncbi.nlm.nih.gov/pubmed/28690599	NUM
dti-2192	420	32	https://doi.org/10.1080/17476348.2018.1506331	https://doi.org/10.1080/17476348.2018.1506331	PROPN
dti-2192	420	33	https://www.ncbi.nlm.nih.gov/pubmed/30056777	https://www.ncbi.nlm.nih.gov/pubmed/30056777	NUM
dti-2192	420	34	https://doi.org/10.1111/j.1600-065x.2012.01151.x	https://doi.org/10.1111/j.1600-065x.2012.01151.x	PROPN
dti-2192	420	35	https://www.ncbi.nlm.nih.gov/pubmed/22889225	https://www.ncbi.nlm.nih.gov/pubmed/22889225	PUNCT
dti-2192	420	36	https://doi.org/10.1111/obr.13034	https://doi.org/10.1111/obr.13034	ADJ
dti-2192	420	37	https://www.ncbi.nlm.nih.gov/pubmed/32281287	https://www.ncbi.nlm.nih.gov/pubmed/32281287	ADV
dti-2192	420	38	https://doi.org/10.1016/s2213-8587(20)30110-8	https://doi.org/10.1016/s2213-8587(20)30110-8	VERB
dti-2192	420	39	https://www.ncbi.nlm.nih.gov/pubmed/32559477	https://www.ncbi.nlm.nih.gov/pubmed/32559477	NOUN
dti-2192	420	40	https://doi.org/10.1038/s41574-020-00462-1	https://doi.org/10.1038/s41574-020-00462-1	NUM
dti-2192	420	41	https://www.ncbi.nlm.nih.gov/pubmed/33479538	https://www.ncbi.nlm.nih.gov/pubmed/33479538	PROPN
dti-2192	420	42	https://doi.org/10.1016/j.metabol.2020.154317	https://doi.org/10.1016/j.metabol.2020.154317	PROPN
dti-2192	420	43	https://www.ncbi.nlm.nih.gov/pubmed/32673651	https://www.ncbi.nlm.nih.gov/pubmed/32673651	NUM
dti-2192	420	44	https://www.ncbi.nlm.nih.gov/pubmed/32712222	https://www.ncbi.nlm.nih.gov/pubmed/32712222	PRON
dti-2192	420	45	https://doi.org/10.1016/j.metabol.2020.154319	https://doi.org/10.1016/j.metabol.2020.154319	PROPN
dti-2192	420	46	https://doi.org/10.1002/oby.22971	https://doi.org/10.1002/oby.22971	PROPN
dti-2192	420	47	https://www.ncbi.nlm.nih.gov/pubmed/32677752	https://www.ncbi.nlm.nih.gov/pubmed/32677752	ADP
dti-2192	420	48	https://doi.org/10.1038/nm0796-800	https://doi.org/10.1038/nm0796-800	PROPN
dti-2192	420	49	https://www.ncbi.nlm.nih.gov/pubmed/8673927	https://www.ncbi.nlm.nih.gov/pubmed/8673927	NUM
dti-2192	420	50	https://doi.org/10.3389/fimmu.2020.573662	https://doi.org/10.3389/fimmu.2020.573662	VERB
dti-2192	420	51	https://www.ncbi.nlm.nih.gov/pubmed/33123152	https://www.ncbi.nlm.nih.gov/pubmed/33123152	PROPN
dti-2192	421	1	https://doi.org/10.1080/08830185.2020.1845518	https://doi.org/10.1080/08830185.2020.1845518	INTJ
dti-2192	421	2	https://www.ncbi.nlm.nih.gov/pubmed/33275480	https://www.ncbi.nlm.nih.gov/pubmed/33275480	NUM
dti-2192	421	3	https://doi.org/10.1111/obr.13128	https://doi.org/10.1111/obr.13128	PROPN
dti-2192	421	4	https://www.ncbi.nlm.nih.gov/pubmed/32845580	https://www.ncbi.nlm.nih.gov/pubmed/32845580	PROPN
dti-2192	421	5	https://doi.org/10.1038/d41586-020-02946-6	https://doi.org/10.1038/d41586-020-02946-6	NUM
dti-2192	421	6	https://www.ncbi.nlm.nih.gov/pubmed/33082543	https://www.ncbi.nlm.nih.gov/pubmed/33082543	NUM
dti-2192	421	7	https://www.ncbi.nlm.nih.gov/pubmed/24798950	https://www.ncbi.nlm.nih.gov/pubmed/24798950	NUM
dti-2192	421	8	https://doi.org/10.1016/j.diabres.2014.04.006	https://doi.org/10.1016/j.diabres.2014.04.006	PROPN
dti-2192	421	9	https://doi.org/10.1590/s1517-86922009000600012	https://doi.org/10.1590/s1517-86922009000600012	NOUN
dti-2192	421	10	https://doi.org/10.1017/s0007114520003311	https://doi.org/10.1017/s0007114520003311	NUM
dti-2192	421	11	https://doi.org/10.1016/j.drudis.2020.01.015	https://doi.org/10.1016/j.drudis.2020.01.015	PROPN
dti-2192	421	12	https://www.ncbi.nlm.nih.gov/pubmed/32006468	https://www.ncbi.nlm.nih.gov/pubmed/32006468	NUM
dti-2192	421	13	https://doi.org/10.1126/science.1085952	https://doi.org/10.1126/science.1085952	PROPN
dti-2192	421	14	https://doi.org/10.1016/j.ijantimicag.2020.106012	https://doi.org/10.1016/j.ijantimicag.2020.106012	PROPN
dti-2192	421	15	https://www.ncbi.nlm.nih.gov/pubmed/32389723	https://www.ncbi.nlm.nih.gov/pubmed/32389723	PUNCT
dti-2192	421	16	https://doi.org/10.1016/j.tim.2016.09.001	https://doi.org/10.1016/j.tim.2016.09.001	PROPN
dti-2192	421	17	https://www.ncbi.nlm.nih.gov/pubmed/27743750	https://www.ncbi.nlm.nih.gov/pubmed/27743750	PRON
dti-2192	421	18	https://doi.org/10.1016/j.ejmech.2020.112711	https://doi.org/10.1016/j.ejmech.2020.112711	VERB
dti-2192	421	19	https://www.ncbi.nlm.nih.gov/pubmed/32810751	https://www.ncbi.nlm.nih.gov/pubmed/32810751	PRON
dti-2192	421	20	https://doi.org/10.1016/j.cell.2020.02.052	https://doi.org/10.1016/j.cell.2020.02.052	PROPN
dti-2192	421	21	https://doi.org/10.1136/bmj.m606	https://doi.org/10.1136/bmj.m606	PROPN
dti-2192	421	22	https://www.ncbi.nlm.nih.gov/pubmed/32075786	https://www.ncbi.nlm.nih.gov/pubmed/32075786	PROPN
dti-2192	421	23	https://doi.org/10.1111/bph.12159	https://doi.org/10.1111/bph.12159	PROPN
dti-2192	421	24	https://www.ncbi.nlm.nih.gov/pubmed/23488800	https://www.ncbi.nlm.nih.gov/pubmed/23488800	X
dti-2192	421	25	https://www.ncbi.nlm.nih.gov/pubmed/18310257	https://www.ncbi.nlm.nih.gov/pubmed/18310257	NUM
dti-2192	422	1	https://doi.org/10.1113/expphysiol.2008.042002	https://doi.org/10.1113/expphysiol.2008.042002	PROPN
dti-2192	422	2	https://www.ncbi.nlm.nih.gov/pubmed/18310257	https://www.ncbi.nlm.nih.gov/pubmed/18310257	NUM
dti-2192	422	3	https://doi.org/10.1161/hypertensionaha.109.140145	https://doi.org/10.1161/hypertensionaha.109.140145	NOUN
dti-2192	422	4	https://www.ncbi.nlm.nih.gov/pubmed/23079502	https://www.ncbi.nlm.nih.gov/pubmed/23079502	X
dti-2192	422	5	https://doi.org/10.1254/jphs.12r03cr	https://doi.org/10.1254/jphs.12r03cr	NOUN
dti-2192	423	1	https://doi.org/10.1161/01.hyp.0000111136.86976.26	https://doi.org/10.1161/01.hyp.0000111136.86976.26	NOUN
dti-2192	423	2	https://doi.org/10.1161/01.hyp.35.6.1270	https://doi.org/10.1161/01.hyp.35.6.1270	PROPN
dti-2192	423	3	https://www.ncbi.nlm.nih.gov/pubmed/10856276	https://www.ncbi.nlm.nih.gov/pubmed/10856276	PROPN
dti-2192	423	4	https://doi.org/10.1038/s41421-020-0156-0	https://doi.org/10.1038/s41421-020-0156-0	NUM
dti-2192	423	5	https://www.ncbi.nlm.nih.gov/pubmed/32194981	https://www.ncbi.nlm.nih.gov/pubmed/32194981	NUM
dti-2192	423	6	https://doi.org/10.3390/ijms18030563	https://doi.org/10.3390/ijms18030563	PROPN
dti-2192	423	7	https://www.ncbi.nlm.nih.gov/pubmed/28273875	https://www.ncbi.nlm.nih.gov/pubmed/28273875	PRON
dti-2192	423	8	https://doi.org/10.1016/s0140-6736(20)30628-0	https://doi.org/10.1016/s0140-6736(20)30628-0	PROPN
dti-2192	423	9	https://www.ncbi.nlm.nih.gov/pubmed/32192578	https://www.ncbi.nlm.nih.gov/pubmed/32192578	NUM
dti-2192	423	10	https://doi.org/10.1101/2020.04.17.046938	https://doi.org/10.1101/2020.04.17.046938	PROPN
dti-2192	423	11	https://doi.org/10.1001/jama.2020.6019	https://doi.org/10.1001/jama.2020.6019	PROPN
dti-2192	423	12	https://www.ncbi.nlm.nih.gov/pubmed/32282022	https://www.ncbi.nlm.nih.gov/pubmed/32282022	X
dti-2192	423	13	https://doi.org/10.20944/preprints202004.0014.v1	https://doi.org/10.20944/preprints202004.0014.v1	DET
dti-2192	423	14	protein	protein	NOUN
dti-2192	423	15	with	with	ADP
dti-2192	423	16	potential	potential	NOUN
dti-2192	423	17	for	for	ADP
dti-2192	423	18	combating	combat	VERB
dti-2192	423	19	sars	sar	NOUN
dti-2192	423	20	-	-	PUNCT
dti-2192	423	21	cov-2	cov-2	NOUN
dti-2192	423	22	infection	infection	NOUN
dti-2192	423	23	in	in	ADP
dti-2192	423	24	obesity12	obesity12	ADJ
dti-2192	423	25	©	©	PROPN
dti-2192	423	26	2021	2021	NUM
dti-2192	423	27	the	the	DET
dti-2192	423	28	authors	author	NOUN
dti-2192	423	29	.	.	PUNCT
dti-2192	424	1	drug	drug	NOUN
dti-2192	424	2	target	target	NOUN
dti-2192	424	3	insights	insight	NOUN
dti-2192	424	4	issn	issn	VERB
dti-2192	424	5	1177	1177	NUM
dti-2192	424	6	-	-	SYM
dti-2192	424	7	3928	3928	NUM
dti-2192	424	8	www.aboutscience.eu/dti	www.aboutscience.eu/dti	NOUN
dti-2192	424	9	drugs	drug	NOUN
dti-2192	424	10	:	:	PUNCT
dti-2192	424	11	insights	insight	NOUN
dti-2192	424	12	from	from	ADP
dti-2192	424	13	structures	structure	NOUN
dti-2192	424	14	of	of	ADP
dti-2192	424	15	protease	protease	NOUN
dti-2192	424	16	and	and	CCONJ
dti-2192	424	17	inhibitors	inhibitor	NOUN
dti-2192	424	18	.	.	PUNCT
dti-2192	425	1	int	int	NOUN
dti-2192	425	2	j	j	PROPN
dti-2192	425	3	antimicrob	antimicrob	PROPN
dti-2192	425	4	agents	agent	NOUN
dti-2192	425	5	.	.	PUNCT
dti-2192	426	1	2020;56(2):106055	2020;56(2):106055	NUM
dti-2192	426	2	.	.	PUNCT
dti-2192	427	1	crossref	crossref	PROPN
dti-2192	427	2	pubmed	pubmed	PROPN
dti-2192	427	3	55	55	NUM
dti-2192	427	4	.	.	PUNCT
dti-2192	428	1	farady	farady	PROPN
dti-2192	428	2	cj	cj	PROPN
dti-2192	428	3	,	,	PUNCT
dti-2192	428	4	craik	craik	PROPN
dti-2192	428	5	cs	cs	PROPN
dti-2192	428	6	.	.	PROPN
dti-2192	428	7	mechanisms	mechanism	NOUN
dti-2192	428	8	of	of	ADP
dti-2192	428	9	macromolecular	macromolecular	ADJ
dti-2192	428	10	protease	protease	NOUN
dti-2192	428	11	inhibitors	inhibitor	NOUN
dti-2192	428	12	.	.	PUNCT
dti-2192	429	1	clin	clin	PROPN
dti-2192	429	2	lymphoma	lymphoma	NOUN
dti-2192	429	3	.	.	PUNCT
dti-2192	430	1	2010;11(17):19	2010;11(17):19	NUM
dti-2192	430	2	-	-	PUNCT
dti-2192	430	3	222341	222341	NUM
dti-2192	430	4	-	-	SYM
dti-2192	430	5	222346	222346	NUM
dti-2192	430	6	.	.	PUNCT
dti-2192	431	1	crossref	crossref	PROPN
dti-2192	431	2	56	56	NUM
dti-2192	431	3	.	.	PUNCT
dti-2192	432	1	laskowski	laskowski	PROPN
dti-2192	432	2	m	m	PROPN
dti-2192	432	3	jr	jr	PROPN
dti-2192	432	4	,	,	PUNCT
dti-2192	432	5	kato	kato	PROPN
dti-2192	432	6	i.	i.	NOUN
dti-2192	432	7	protein	protein	NOUN
dti-2192	432	8	inhibitors	inhibitor	NOUN
dti-2192	432	9	of	of	ADP
dti-2192	432	10	proteinases	proteinase	NOUN
dti-2192	432	11	.	.	PUNCT
dti-2192	432	12	annu	annu	PROPN
dti-2192	432	13	rev	rev	VERB
dti-2192	432	14	biochem	biochem	PROPN
dti-2192	432	15	.	.	PUNCT
dti-2192	433	1	1980;49(1):593	1980;49(1):593	NUM
dti-2192	433	2	-	-	SYM
dti-2192	433	3	626	626	NUM
dti-2192	433	4	.	.	PUNCT
dti-2192	434	1	crossref	crossref	PROPN
dti-2192	434	2	pubmed	pubmed	PROPN
dti-2192	434	3	57	57	NUM
dti-2192	434	4	.	.	PUNCT
dti-2192	435	1	barkia	barkia	PROPN
dti-2192	435	2	i	i	PROPN
dti-2192	435	3	,	,	PUNCT
dti-2192	435	4	ketata	ketata	PROPN
dti-2192	435	5	bouaziz	bouaziz	PROPN
dti-2192	435	6	h	h	NOUN
dti-2192	435	7	,	,	PUNCT
dti-2192	435	8	sellami	sellami	VERB
dti-2192	435	9	boudawara	boudawara	PROPN
dti-2192	435	10	t	t	PROPN
dti-2192	435	11	,	,	PUNCT
dti-2192	435	12	aleya	aleya	PROPN
dti-2192	435	13	l	l	PROPN
dti-2192	435	14	,	,	PUNCT
dti-2192	435	15	gargouri	gargouri	PROPN
dti-2192	435	16	af	af	PROPN
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dti-2192	435	18	saari	saari	PROPN
dti-2192	435	19	n.	n.	PROPN
dti-2192	435	20	acute	acute	PROPN
dti-2192	435	21	oral	oral	ADJ
dti-2192	435	22	toxicity	toxicity	NOUN
dti-2192	435	23	study	study	NOUN
dti-2192	435	24	on	on	ADP
dti-2192	435	25	wistar	wistar	PROPN
dti-2192	435	26	rats	rat	NOUN
dti-2192	435	27	fed	feed	VERB
dti-2192	435	28	microalgal	microalgal	ADJ
dti-2192	435	29	protein	protein	NOUN
dti-2192	435	30	hydrolysates	hydrolysate	NOUN
dti-2192	435	31	from	from	ADP
dti-2192	435	32	bellerochea	bellerochea	PROPN
dti-2192	435	33	malleus	malleus	PROPN
dti-2192	435	34	.	.	PUNCT
dti-2192	436	1	environ	environ	PROPN
dti-2192	436	2	sci	sci	PROPN
dti-2192	436	3	pollut	pollut	PROPN
dti-2192	436	4	res	re	NOUN
dti-2192	436	5	int	int	NOUN
dti-2192	436	6	.	.	PUNCT
dti-2192	437	1	2020;27(16):19087	2020;27(16):19087	NUM
dti-2192	437	2	-	-	SYM
dti-2192	437	3	19094	19094	NUM
dti-2192	437	4	.	.	PUNCT
dti-2192	438	1	crossref	crossref	PROPN
dti-2192	438	2	pubmed	pubmed	PROPN
dti-2192	438	3	58	58	NUM
dti-2192	438	4	.	.	PUNCT
dti-2192	439	1	souza	souza	PROPN
dti-2192	439	2	dd	dd	PROPN
dti-2192	439	3	,	,	PUNCT
dti-2192	439	4	brandão	brandão	PROPN
dti-2192	439	5	-	-	PUNCT
dti-2192	439	6	costa	costa	PROPN
dti-2192	439	7	rmp	rmp	PROPN
dti-2192	439	8	,	,	PUNCT
dti-2192	439	9	albuquerque	albuquerque	PROPN
dti-2192	439	10	wwc	wwc	PROPN
dti-2192	439	11	,	,	PUNCT
dti-2192	439	12	porto	porto	PROPN
dti-2192	439	13	alf	alf	PROPN
dti-2192	439	14	.	.	PUNCT
dti-2192	439	15	partial	partial	ADJ
dti-2192	439	16	purification	purification	NOUN
dti-2192	439	17	and	and	CCONJ
dti-2192	439	18	characterization	characterization	NOUN
dti-2192	439	19	of	of	ADP
dti-2192	439	20	a	a	DET
dti-2192	439	21	trypsin	trypsin	NOUN
dti-2192	439	22	inhibitor	inhibitor	NOUN
dti-2192	439	23	isolated	isolate	VERB
dti-2192	439	24	from	from	ADP
dti-2192	439	25	adenanthera	adenanthera	PROPN
dti-2192	439	26	pavonina	pavonina	PROPN
dti-2192	439	27	l.	l.	PROPN
dti-2192	439	28	seeds	seed	NOUN
dti-2192	439	29	.	.	PUNCT
dti-2192	440	1	s	s	PROPN
dti-2192	440	2	afr	afr	PROPN
dti-2192	440	3	j	j	PROPN
dti-2192	440	4	bot	bot	PROPN
dti-2192	440	5	.	.	PUNCT
dti-2192	441	1	2016;104:30	2016;104:30	NUM
dti-2192	441	2	-	-	SYM
dti-2192	441	3	34	34	NUM
dti-2192	441	4	.	.	PUNCT
dti-2192	442	1	crossref	crossref	PROPN
dti-2192	442	2	59	59	NUM
dti-2192	442	3	.	.	PUNCT
dti-2192	443	1	cristina	cristina	PROPN
dti-2192	443	2	oliveira	oliveira	PROPN
dti-2192	443	3	de	de	PROPN
dti-2192	443	4	lima	lima	PROPN
dti-2192	443	5	v	v	PROPN
dti-2192	443	6	,	,	PUNCT
dti-2192	443	7	piuvezam	piuvezam	ADP
dti-2192	443	8	g	g	PROPN
dti-2192	443	9	,	,	PUNCT
dti-2192	443	10	leal	leal	PROPN
dti-2192	443	11	lima	lima	PROPN
dti-2192	443	12	maciel	maciel	PROPN
dti-2192	443	13	b	b	PROPN
dti-2192	443	14	,	,	PUNCT
dti-2192	443	15	heloneida	heloneida	PROPN
dti-2192	443	16	de	de	PROPN
dti-2192	443	17	araújo	araújo	PROPN
dti-2192	443	18	morais	morais	PROPN
dti-2192	443	19	a.	a.	PROPN
dti-2192	443	20	trypsin	trypsin	PROPN
dti-2192	443	21	inhibitors	inhibitor	NOUN
dti-2192	443	22	:	:	PUNCT
dti-2192	443	23	promising	promise	VERB
dti-2192	443	24	candidate	candidate	NOUN
dti-2192	443	25	satietogenic	satietogenic	ADJ
dti-2192	443	26	proteins	protein	NOUN
dti-2192	443	27	as	as	ADP
dti-2192	443	28	complementary	complementary	ADJ
dti-2192	443	29	treatment	treatment	NOUN
dti-2192	443	30	for	for	ADP
dti-2192	443	31	obesity	obesity	NOUN
dti-2192	443	32	and	and	CCONJ
dti-2192	443	33	metabolic	metabolic	NOUN
dti-2192	443	34	disorders	disorder	NOUN
dti-2192	443	35	?	?	PUNCT
dti-2192	444	1	j	j	NOUN
dti-2192	444	2	enzyme	enzyme	NOUN
dti-2192	444	3	inhib	inhib	VERB
dti-2192	444	4	med	med	ADJ
dti-2192	444	5	chem	chem	NOUN
dti-2192	444	6	.	.	PUNCT
dti-2192	445	1	2019;34(1):405	2019;34(1):405	NOUN
dti-2192	445	2	-	-	SYM
dti-2192	445	3	419	419	NUM
dti-2192	445	4	.	.	PUNCT
dti-2192	446	1	crossref	crossref	PROPN
dti-2192	446	2	pubmed	pubmed	PROPN
dti-2192	446	3	60	60	PROPN
dti-2192	446	4	.	.	PUNCT
dti-2192	447	1	lewis	lewis	PROPN
dti-2192	447	2	gp	gp	PROPN
dti-2192	447	3	.	.	PUNCT
dti-2192	447	4	lista	lista	PROPN
dti-2192	447	5	de	de	PROPN
dti-2192	447	6	espécies	espécies	PROPN
dti-2192	447	7	da	da	PROPN
dti-2192	447	8	flora	flora	NOUN
dti-2192	447	9	do	do	VERB
dti-2192	447	10	brasil	brasil	PROPN
dti-2192	447	11	.	.	PUNCT
dti-2192	448	1	jardim	jardim	PROPN
dti-2192	448	2	botânico	botânico	PROPN
dti-2192	448	3	do	do	VERB
dti-2192	448	4	rio	rio	PROPN
dti-2192	448	5	de	de	PROPN
dti-2192	448	6	janeiro	janeiro	PROPN
dti-2192	448	7	.	.	PUNCT
dti-2192	449	1	crossref	crossref	PROPN
dti-2192	449	2	61	61	NUM
dti-2192	449	3	.	.	PUNCT
dti-2192	450	1	ribeiro	ribeiro	PROPN
dti-2192	450	2	ja	ja	PROPN
dti-2192	450	3	,	,	PUNCT
dti-2192	450	4	serquiz	serquiz	PROPN
dti-2192	450	5	ac	ac	PROPN
dti-2192	450	6	,	,	PUNCT
dti-2192	450	7	silva	silva	PROPN
dti-2192	450	8	pf	pf	PROPN
dti-2192	450	9	,	,	PUNCT
dti-2192	450	10	et	et	PROPN
dti-2192	450	11	al	al	PROPN
dti-2192	450	12	.	.	PROPN
dti-2192	450	13	trypsin	trypsin	PROPN
dti-2192	450	14	inhibitor	inhibitor	NOUN
dti-2192	450	15	from	from	ADP
dti-2192	450	16	tamarindus	tamarindus	PROPN
dti-2192	450	17	indica	indica	PROPN
dti-2192	450	18	l.	l.	PROPN
dti-2192	450	19	seeds	seed	NOUN
dti-2192	450	20	reduces	reduce	VERB
dti-2192	450	21	weight	weight	NOUN
dti-2192	450	22	gain	gain	NOUN
dti-2192	450	23	and	and	CCONJ
dti-2192	450	24	food	food	NOUN
dti-2192	450	25	consumption	consumption	NOUN
dti-2192	450	26	and	and	CCONJ
dti-2192	450	27	increases	increase	VERB
dti-2192	450	28	plasmatic	plasmatic	ADJ
dti-2192	450	29	cholecystokinin	cholecystokinin	ADJ
dti-2192	450	30	levels	level	NOUN
dti-2192	450	31	.	.	PUNCT
dti-2192	451	1	clinics	clinic	NOUN
dti-2192	451	2	(	(	PUNCT
dti-2192	451	3	são	são	NOUN
dti-2192	451	4	paulo	paulo	PROPN
dti-2192	451	5	)	)	PUNCT
dti-2192	451	6	.	.	PUNCT
dti-2192	452	1	2015;70(2):136	2015;70(2):136	NUM
dti-2192	452	2	-	-	SYM
dti-2192	452	3	143	143	NUM
dti-2192	452	4	.	.	PUNCT
dti-2192	453	1	crossref	crossref	PROPN
dti-2192	453	2	pubmed	pubmed	PROPN
dti-2192	453	3	62	62	NUM
dti-2192	453	4	.	.	PUNCT
dti-2192	454	1	carvalho	carvalho	PROPN
dti-2192	454	2	fmcc	fmcc	PROPN
dti-2192	454	3	,	,	PUNCT
dti-2192	454	4	lima	lima	PROPN
dti-2192	454	5	vcoo	vcoo	NOUN
dti-2192	454	6	,	,	PUNCT
dti-2192	454	7	costa	costa	PROPN
dti-2192	454	8	is	be	AUX
dti-2192	454	9	,	,	PUNCT
dti-2192	454	10	et	et	PROPN
dti-2192	454	11	al	al	PROPN
dti-2192	454	12	.	.	PUNCT
dti-2192	455	1	a	a	DET
dti-2192	455	2	trypsin	trypsin	NOUN
dti-2192	455	3	inhibitor	inhibitor	NOUN
dti-2192	455	4	from	from	ADP
dti-2192	455	5	tamarind	tamarind	NOUN
dti-2192	455	6	reduces	reduce	VERB
dti-2192	455	7	food	food	NOUN
dti-2192	455	8	intake	intake	NOUN
dti-2192	455	9	and	and	CCONJ
dti-2192	455	10	improves	improve	VERB
dti-2192	455	11	inflammatory	inflammatory	ADJ
dti-2192	455	12	status	status	NOUN
dti-2192	455	13	in	in	ADP
dti-2192	455	14	rats	rat	NOUN
dti-2192	455	15	with	with	ADP
dti-2192	455	16	metabolic	metabolic	NOUN
dti-2192	455	17	syndrome	syndrome	NOUN
dti-2192	455	18	regardless	regardless	ADV
dti-2192	455	19	of	of	ADP
dti-2192	455	20	weight	weight	NOUN
dti-2192	455	21	loss	loss	NOUN
dti-2192	455	22	.	.	PUNCT
dti-2192	456	1	nutrients	nutrient	NOUN
dti-2192	456	2	.	.	PUNCT
dti-2192	457	1	2016;8(10):1	2016;8(10):1	NUM
dti-2192	457	2	-	-	SYM
dti-2192	457	3	14	14	NUM
dti-2192	457	4	.	.	PUNCT
dti-2192	458	1	crossref	crossref	PROPN
dti-2192	458	2	pubmed	pubmed	PROPN
dti-2192	458	3	63	63	NUM
dti-2192	458	4	.	.	PUNCT
dti-2192	459	1	costa	costa	PROPN
dti-2192	459	2	is	be	AUX
dti-2192	459	3	,	,	PUNCT
dti-2192	459	4	medeiros	medeiros	PROPN
dti-2192	459	5	af	af	PROPN
dti-2192	459	6	,	,	PUNCT
dti-2192	459	7	carvalho	carvalho	PROPN
dti-2192	459	8	fmc	fmc	PROPN
dti-2192	459	9	,	,	PUNCT
dti-2192	459	10	et	et	PROPN
dti-2192	459	11	al	al	PROPN
dti-2192	459	12	.	.	PROPN
dti-2192	459	13	satietogenic	satietogenic	ADJ
dti-2192	459	14	protein	protein	NOUN
dti-2192	459	15	from	from	ADP
dti-2192	459	16	tamarind	tamarind	NOUN
dti-2192	459	17	seeds	seed	NOUN
dti-2192	459	18	decreases	decrease	VERB
dti-2192	459	19	food	food	NOUN
dti-2192	459	20	intake	intake	NOUN
dti-2192	459	21	,	,	PUNCT
dti-2192	459	22	leptin	leptin	NOUN
dti-2192	459	23	plasma	plasma	NOUN
dti-2192	459	24	and	and	CCONJ
dti-2192	459	25	cck-1r	cck-1r	ADJ
dti-2192	459	26	gene	gene	NOUN
dti-2192	459	27	expression	expression	NOUN
dti-2192	459	28	in	in	ADP
dti-2192	459	29	obese	obese	ADJ
dti-2192	459	30	wistar	wistar	PROPN
dti-2192	459	31	rats	rat	NOUN
dti-2192	459	32	.	.	PUNCT
dti-2192	460	1	obes	obe	NOUN
dti-2192	460	2	facts	fact	NOUN
dti-2192	460	3	.	.	PUNCT
dti-2192	461	1	2018;11(6):440	2018;11(6):440	NUM
dti-2192	461	2	-	-	SYM
dti-2192	461	3	453	453	NUM
dti-2192	461	4	.	.	PUNCT
dti-2192	462	1	crossref	crossref	PROPN
dti-2192	462	2	pubmed	pubmed	PROPN
dti-2192	462	3	64	64	NUM
dti-2192	462	4	.	.	PUNCT
dti-2192	463	1	luz	luz	PROPN
dti-2192	463	2	abs	abs	PROPN
dti-2192	463	3	,	,	PUNCT
dti-2192	463	4	dos	do	NOUN
dti-2192	463	5	santos	santos	PROPN
dti-2192	463	6	figueredo	figueredo	PROPN
dti-2192	463	7	jb	jb	PROPN
dti-2192	463	8	,	,	PUNCT
dti-2192	463	9	salviano	salviano	PROPN
dti-2192	463	10	bdpd	bdpd	PROPN
dti-2192	463	11	,	,	PUNCT
dti-2192	463	12	et	et	PROPN
dti-2192	463	13	al	al	PROPN
dti-2192	463	14	.	.	PROPN
dti-2192	463	15	adipocytes	adipocytes	PROPN
dti-2192	463	16	and	and	CCONJ
dti-2192	463	17	intestinal	intestinal	ADJ
dti-2192	463	18	epithelium	epithelium	NOUN
dti-2192	463	19	dysfunctions	dysfunction	NOUN
dti-2192	463	20	linking	link	VERB
dti-2192	463	21	obesity	obesity	NOUN
dti-2192	463	22	to	to	ADP
dti-2192	463	23	inflammation	inflammation	NOUN
dti-2192	463	24	induced	induce	VERB
dti-2192	463	25	by	by	ADP
dti-2192	463	26	high	high	ADJ
dti-2192	463	27	glycemic	glycemic	ADJ
dti-2192	463	28	index	index	NOUN
dti-2192	463	29	pellet	pellet	NOUN
dti-2192	463	30	-	-	PUNCT
dti-2192	463	31	diet	diet	NOUN
dti-2192	463	32	in	in	ADP
dti-2192	463	33	wistar	wistar	PROPN
dti-2192	463	34	rats	rat	NOUN
dti-2192	463	35	.	.	PUNCT
dti-2192	464	1	biosci	biosci	PROPN
dti-2192	464	2	rep	rep	PROPN
dti-2192	464	3	.	.	PROPN
dti-2192	464	4	2018;38(3):1	2018;38(3):1	NUM
dti-2192	464	5	-	-	SYM
dti-2192	464	6	15	15	NUM
dti-2192	464	7	.	.	PUNCT
dti-2192	465	1	crossref	crossref	PROPN
dti-2192	465	2	pubmed	pubmed	PROPN
dti-2192	465	3	65	65	NUM
dti-2192	465	4	.	.	PUNCT
dti-2192	466	1	li	li	PROPN
dti-2192	466	2	s	s	PROPN
dti-2192	466	3	,	,	PUNCT
dti-2192	466	4	liu	liu	PROPN
dti-2192	466	5	l	l	PROPN
dti-2192	466	6	,	,	PUNCT
dti-2192	466	7	he	he	PRON
dti-2192	466	8	g	g	PROPN
dti-2192	466	9	,	,	PUNCT
dti-2192	466	10	wu	wu	PROPN
dti-2192	466	11	j.	j.	PROPN
dti-2192	466	12	molecular	molecular	ADJ
dti-2192	466	13	targets	target	NOUN
dti-2192	466	14	and	and	CCONJ
dti-2192	466	15	mechanisms	mechanism	NOUN
dti-2192	466	16	of	of	ADP
dti-2192	466	17	bioactive	bioactive	ADJ
dti-2192	466	18	peptides	peptide	NOUN
dti-2192	466	19	against	against	ADP
dti-2192	466	20	metabolic	metabolic	NOUN
dti-2192	466	21	syndromes	syndrome	NOUN
dti-2192	466	22	.	.	PUNCT
dti-2192	467	1	food	food	NOUN
dti-2192	467	2	funct	funct	NOUN
dti-2192	467	3	.	.	PUNCT
dti-2192	468	1	2018;9(1):42	2018;9(1):42	NUM
dti-2192	468	2	-	-	SYM
dti-2192	468	3	52	52	NUM
dti-2192	468	4	.	.	PUNCT
dti-2192	469	1	crossref	crossref	PROPN
dti-2192	469	2	pubmed	pubmed	PROPN
dti-2192	469	3	66	66	NUM
dti-2192	469	4	.	.	PUNCT
dti-2192	470	1	de	de	PROPN
dti-2192	470	2	queiroz	queiroz	PROPN
dti-2192	470	3	jlc	jlc	PROPN
dti-2192	470	4	,	,	PUNCT
dti-2192	470	5	de	de	PROPN
dti-2192	470	6	araújo	araújo	PROPN
dti-2192	470	7	costa	costa	PROPN
dti-2192	470	8	ro	ro	PROPN
dti-2192	470	9	,	,	PUNCT
dti-2192	470	10	rodrigues	rodrigues	PROPN
dti-2192	470	11	matias	matias	PROPN
dti-2192	470	12	ll	ll	PROPN
dti-2192	470	13	,	,	PUNCT
dti-2192	470	14	et	et	PROPN
dti-2192	470	15	al	al	PROPN
dti-2192	470	16	.	.	PUNCT
dti-2192	471	1	chitosan	chitosan	PROPN
dti-2192	471	2	-	-	PUNCT
dti-2192	471	3	whey	whey	PROPN
dti-2192	471	4	protein	protein	NOUN
dti-2192	471	5	nanoparticles	nanoparticle	NOUN
dti-2192	471	6	improve	improve	VERB
dti-2192	471	7	encapsulation	encapsulation	NOUN
dti-2192	471	8	efficiency	efficiency	NOUN
dti-2192	471	9	and	and	CCONJ
dti-2192	471	10	stability	stability	NOUN
dti-2192	471	11	of	of	ADP
dti-2192	471	12	a	a	DET
dti-2192	471	13	trypsin	trypsin	NOUN
dti-2192	471	14	inhibitor	inhibitor	NOUN
dti-2192	471	15	isolated	isolate	VERB
dti-2192	471	16	from	from	ADP
dti-2192	471	17	tamarindus	tamarindus	PROPN
dti-2192	471	18	indica	indica	PROPN
dti-2192	471	19	l.	l.	PROPN
dti-2192	471	20	food	food	PROPN
dti-2192	471	21	hydrocoll	hydrocoll	PROPN
dti-2192	471	22	.	.	PUNCT
dti-2192	472	1	2018;84:247	2018;84:247	NUM
dti-2192	472	2	-	-	SYM
dti-2192	472	3	256	256	NUM
dti-2192	472	4	.	.	PUNCT
dti-2192	473	1	crossref	crossref	PROPN
dti-2192	473	2	67	67	NUM
dti-2192	473	3	.	.	PUNCT
dti-2192	474	1	costa	costa	PROPN
dti-2192	474	2	roa	roa	PROPN
dti-2192	474	3	.	.	PUNCT
dti-2192	475	1	identification	identification	NOUN
dti-2192	475	2	of	of	ADP
dti-2192	475	3	safety	safety	NOUN
dti-2192	475	4	and	and	CCONJ
dti-2192	475	5	potential	potential	ADJ
dti-2192	475	6	clinical	clinical	ADJ
dti-2192	475	7	application	application	NOUN
dti-2192	475	8	of	of	ADP
dti-2192	475	9	nanoparticles	nanoparticle	NOUN
dti-2192	475	10	loaded	load	VERB
dti-2192	475	11	with	with	ADP
dti-2192	475	12	a	a	DET
dti-2192	475	13	trypsin	trypsin	NOUN
dti-2192	475	14	inhibitor	inhibitor	NOUN
dti-2192	475	15	isolated	isolate	VERB
dti-2192	475	16	from	from	ADP
dti-2192	475	17	tamarind	tamarind	NOUN
dti-2192	475	18	seeds	seed	NOUN
dti-2192	475	19	(	(	PUNCT
dti-2192	475	20	tamarindus	tamarindus	INTJ
dti-2192	475	21	indica	indica	PROPN
dti-2192	475	22	l.	l.	PROPN
dti-2192	475	23	)	)	PUNCT
dti-2192	475	24	.	.	PUNCT
dti-2192	476	1	dissertation	dissertation	NOUN
dti-2192	476	2	.	.	PUNCT
dti-2192	477	1	published	publish	VERB
dti-2192	477	2	online	online	ADJ
dti-2192	477	3	2019	2019	NUM
dti-2192	477	4	.	.	PUNCT
dti-2192	478	1	crossref	crossref	PROPN
dti-2192	478	2	68	68	NUM
dti-2192	478	3	.	.	PUNCT
dti-2192	479	1	matias	matias	PROPN
dti-2192	479	2	llr	llr	PROPN
dti-2192	479	3	,	,	PUNCT
dti-2192	479	4	costa	costa	PROPN
dti-2192	479	5	roa	roa	PROPN
dti-2192	479	6	,	,	PUNCT
dti-2192	479	7	passos	passos	PROPN
dti-2192	479	8	ts	ts	PROPN
dti-2192	479	9	,	,	PUNCT
dti-2192	479	10	et	et	PROPN
dti-2192	479	11	al	al	PROPN
dti-2192	479	12	.	.	PUNCT
dti-2192	480	1	tamarind	tamarind	NOUN
dti-2192	480	2	trypsin	trypsin	NOUN
dti-2192	480	3	inhibitor	inhibitor	NOUN
dti-2192	480	4	in	in	ADP
dti-2192	480	5	chitosan	chitosan	NOUN
dti-2192	480	6	-	-	PUNCT
dti-2192	480	7	whey	whey	NOUN
dti-2192	480	8	protein	protein	NOUN
dti-2192	480	9	nanoparticles	nanoparticle	NOUN
dti-2192	480	10	reduces	reduce	VERB
dti-2192	480	11	fasting	fast	VERB
dti-2192	480	12	blood	blood	NOUN
dti-2192	480	13	glucose	glucose	NOUN
dti-2192	480	14	levels	level	NOUN
dti-2192	480	15	without	without	ADP
dti-2192	480	16	compromising	compromise	VERB
dti-2192	480	17	insulinemia	insulinemia	NOUN
dti-2192	480	18	:	:	PUNCT
dti-2192	480	19	a	a	DET
dti-2192	480	20	preclinical	preclinical	ADJ
dti-2192	480	21	study	study	NOUN
dti-2192	480	22	.	.	PUNCT
dti-2192	481	1	nutrients	nutrient	NOUN
dti-2192	481	2	.	.	PUNCT
dti-2192	482	1	2019;11(11):2770	2019;11(11):2770	X
dti-2192	482	2	.	.	X
dti-2192	482	3	crossref	crossref	PROPN
dti-2192	482	4	pubmed	pubmed	PROPN
dti-2192	482	5	69	69	NUM
dti-2192	482	6	.	.	PUNCT
dti-2192	483	1	santos	santos	PROPN
dti-2192	483	2	ea	ea	PROPN
dti-2192	483	3	,	,	PUNCT
dti-2192	483	4	oliveira	oliveira	PROPN
dti-2192	483	5	as	as	ADP
dti-2192	483	6	,	,	PUNCT
dti-2192	483	7	arajo	arajo	ADP
dti-2192	483	8	rablo	rablo	NOUN
dti-2192	483	9	lm	lm	PROPN
dti-2192	483	10	,	,	PUNCT
dti-2192	483	11	ferreira	ferreira	PROPN
dti-2192	483	12	a	a	PROPN
dti-2192	483	13	,	,	PUNCT
dti-2192	483	14	arajo	arajo	ADP
dti-2192	483	15	morais	morais	PROPN
dti-2192	483	16	ah	ah	INTJ
dti-2192	483	17	.	.	PUNCT
dti-2192	484	1	affinity	affinity	NOUN
dti-2192	484	2	chromatography	chromatography	NOUN
dti-2192	484	3	as	as	ADP
dti-2192	484	4	a	a	DET
dti-2192	484	5	key	key	ADJ
dti-2192	484	6	tool	tool	NOUN
dti-2192	484	7	to	to	PART
dti-2192	484	8	purify	purify	VERB
dti-2192	484	9	protein	protein	NOUN
dti-2192	484	10	protease	protease	NOUN
dti-2192	484	11	inhibitors	inhibitor	NOUN
dti-2192	484	12	from	from	ADP
dti-2192	484	13	plants	plant	NOUN
dti-2192	484	14	.	.	PUNCT
dti-2192	485	1	in	in	ADP
dti-2192	485	2	:	:	PUNCT
dti-2192	485	3	affinity	affinity	NOUN
dti-2192	485	4	chromatography	chromatography	NOUN
dti-2192	485	5	.	.	PUNCT
dti-2192	486	1	intech	intech	PROPN
dti-2192	486	2	;	;	PUNCT
dti-2192	486	3	2012:35	2012:35	NUM
dti-2192	486	4	.	.	PUNCT
dti-2192	487	1	crossref	crossref	PROPN
dti-2192	487	2	70	70	NUM
dti-2192	487	3	.	.	PUNCT
dti-2192	488	1	medeiros	medeiros	PROPN
dti-2192	488	2	af	af	PROPN
dti-2192	488	3	,	,	PUNCT
dti-2192	488	4	costa	costa	PROPN
dti-2192	488	5	is	be	AUX
dti-2192	488	6	,	,	PUNCT
dti-2192	488	7	carvalho	carvalho	PROPN
dti-2192	488	8	fmc	fmc	PROPN
dti-2192	488	9	,	,	PUNCT
dti-2192	488	10	et	et	PROPN
dti-2192	488	11	al	al	PROPN
dti-2192	488	12	.	.	PUNCT
dti-2192	489	1	biochemical	biochemical	ADJ
dti-2192	489	2	characterisation	characterisation	NOUN
dti-2192	489	3	of	of	ADP
dti-2192	489	4	a	a	DET
dti-2192	489	5	kunitz	kunitz	NOUN
dti-2192	489	6	-	-	PUNCT
dti-2192	489	7	type	type	NOUN
dti-2192	489	8	inhibitor	inhibitor	NOUN
dti-2192	489	9	from	from	ADP
dti-2192	489	10	tamarindus	tamarindus	PROPN
dti-2192	489	11	indica	indica	PROPN
dti-2192	489	12	l.	l.	PROPN
dti-2192	489	13	seeds	seed	NOUN
dti-2192	489	14	and	and	CCONJ
dti-2192	489	15	its	its	PRON
dti-2192	489	16	efficacy	efficacy	NOUN
dti-2192	489	17	in	in	ADP
dti-2192	489	18	reducing	reduce	VERB
dti-2192	489	19	plasma	plasma	NOUN
dti-2192	489	20	leptin	leptin	NOUN
dti-2192	489	21	in	in	ADP
dti-2192	489	22	an	an	DET
dti-2192	489	23	experimental	experimental	ADJ
dti-2192	489	24	model	model	NOUN
dti-2192	489	25	of	of	ADP
dti-2192	489	26	obesity	obesity	NOUN
dti-2192	489	27	.	.	PUNCT
dti-2192	490	1	j	j	PROPN
dti-2192	490	2	enzyme	enzyme	NOUN
dti-2192	490	3	inhib	inhib	VERB
dti-2192	490	4	med	med	ADJ
dti-2192	490	5	chem	chem	NOUN
dti-2192	490	6	.	.	PUNCT
dti-2192	491	1	2018;33(1):334	2018;33(1):334	NUM
dti-2192	491	2	-	-	PUNCT
dti-2192	491	3	348	348	NUM
dti-2192	491	4	.	.	PUNCT
dti-2192	492	1	crossref	crossref	PROPN
dti-2192	492	2	pubmed	pubmed	PROPN
dti-2192	492	3	71	71	NUM
dti-2192	492	4	.	.	PUNCT
dti-2192	493	1	carvalho	carvalho	PROPN
dti-2192	493	2	fmc	fmc	PROPN
dti-2192	493	3	,	,	PUNCT
dti-2192	493	4	lima	lima	PROPN
dti-2192	493	5	vco	vco	PROPN
dti-2192	493	6	,	,	PUNCT
dti-2192	493	7	costa	costa	PROPN
dti-2192	493	8	is	be	AUX
dti-2192	493	9	,	,	PUNCT
dti-2192	493	10	et	et	PROPN
dti-2192	493	11	al	al	PROPN
dti-2192	493	12	.	.	PUNCT
dti-2192	494	1	anti	anti	PROPN
dti-2192	494	2	-	-	ADJ
dti-2192	494	3	tnf	tnf	ADJ
dti-2192	494	4	-	-	PUNCT
dti-2192	494	5	α	α	PROPN
dti-2192	494	6	agent	agent	NOUN
dti-2192	494	7	tamarind	tamarind	NOUN
dti-2192	494	8	kunitz	kunitz	PROPN
dti-2192	494	9	trypsin	trypsin	PROPN
dti-2192	494	10	inhibitor	inhibitor	NOUN
dti-2192	494	11	improves	improve	VERB
dti-2192	494	12	lipid	lipid	NOUN
dti-2192	494	13	profile	profile	NOUN
dti-2192	494	14	of	of	ADP
dti-2192	494	15	wistar	wistar	PROPN
dti-2192	494	16	rats	rat	NOUN
dti-2192	494	17	presenting	present	VERB
dti-2192	494	18	dyslipidemia	dyslipidemia	NOUN
dti-2192	494	19	and	and	CCONJ
dti-2192	494	20	diet	diet	NOUN
dti-2192	494	21	-	-	PUNCT
dti-2192	494	22	induced	induce	VERB
dti-2192	494	23	obesity	obesity	NOUN
dti-2192	494	24	regardless	regardless	ADV
dti-2192	494	25	of	of	ADP
dti-2192	494	26	ppar	ppar	NOUN
dti-2192	494	27	-	-	PUNCT
dti-2192	494	28	γ	γ	NOUN
dti-2192	494	29	induction	induction	NOUN
dti-2192	494	30	.	.	PUNCT
dti-2192	495	1	nutrients	nutrient	NOUN
dti-2192	495	2	.	.	PUNCT
dti-2192	496	1	2019;11(3):e512	2019;11(3):e512	ADJ
dti-2192	496	2	.	.	PUNCT
dti-2192	497	1	crossref	crossref	PROPN
dti-2192	497	2	pubmed	pubmed	PROPN
dti-2192	497	3	72	72	NUM
dti-2192	497	4	.	.	PUNCT
dti-2192	498	1	winer	winer	NOUN
dti-2192	498	2	da	da	PROPN
dti-2192	498	3	,	,	PUNCT
dti-2192	498	4	luck	luck	NOUN
dti-2192	498	5	h	h	NOUN
dti-2192	498	6	,	,	PUNCT
dti-2192	498	7	tsai	tsai	PROPN
dti-2192	498	8	s	s	PROPN
dti-2192	498	9	,	,	PUNCT
dti-2192	498	10	winer	winer	NOUN
dti-2192	498	11	s.	s.	PROPN
dti-2192	498	12	the	the	DET
dti-2192	498	13	intestinal	intestinal	ADJ
dti-2192	498	14	immune	immune	ADJ
dti-2192	498	15	system	system	NOUN
dti-2192	498	16	in	in	ADP
dti-2192	498	17	obesity	obesity	NOUN
dti-2192	498	18	and	and	CCONJ
dti-2192	498	19	insulin	insulin	NOUN
dti-2192	498	20	resistance	resistance	NOUN
dti-2192	498	21	.	.	PUNCT
dti-2192	499	1	cell	cell	NOUN
dti-2192	499	2	metab	metab	NOUN
dti-2192	499	3	.	.	PUNCT
dti-2192	500	1	2016;23(3	2016;23(3	NUM
dti-2192	500	2	):	):	PUNCT
dti-2192	500	3	413	413	NUM
dti-2192	500	4	-	-	SYM
dti-2192	500	5	426	426	NUM
dti-2192	500	6	.	.	PUNCT
dti-2192	501	1	crossref	crossref	PROPN
dti-2192	501	2	pubmed	pubmed	PROPN
dti-2192	501	3	73	73	NUM
dti-2192	501	4	.	.	PUNCT
dti-2192	502	1	maurizi	maurizi	PROPN
dti-2192	502	2	g	g	PROPN
dti-2192	502	3	,	,	PUNCT
dti-2192	502	4	della	della	PROPN
dti-2192	502	5	guardia	guardia	PROPN
dti-2192	502	6	l	l	PROPN
dti-2192	502	7	,	,	PUNCT
dti-2192	502	8	maurizi	maurizi	PROPN
dti-2192	502	9	a	a	X
dti-2192	502	10	,	,	PUNCT
dti-2192	502	11	poloni	poloni	PROPN
dti-2192	502	12	a.	a.	NOUN
dti-2192	502	13	adipocytes	adipocyte	NOUN
dti-2192	502	14	properties	property	NOUN
dti-2192	502	15	and	and	CCONJ
dti-2192	502	16	crosstalk	crosstalk	VERB
dti-2192	502	17	with	with	ADP
dti-2192	502	18	immune	immune	ADJ
dti-2192	502	19	system	system	NOUN
dti-2192	502	20	in	in	ADP
dti-2192	502	21	obesity	obesity	NOUN
dti-2192	502	22	related	relate	VERB
dti-2192	502	23	inflammation	inflammation	NOUN
dti-2192	502	24	.	.	PUNCT
dti-2192	503	1	j	j	PROPN
dti-2192	503	2	cell	cell	NOUN
dti-2192	503	3	physiol	physiol	PROPN
dti-2192	503	4	.	.	PUNCT
dti-2192	504	1	2018;233(1):88	2018;233(1):88	X
dti-2192	504	2	-	-	SYM
dti-2192	504	3	97	97	NUM
dti-2192	504	4	.	.	PUNCT
dti-2192	505	1	crossref	crossref	PROPN
dti-2192	505	2	pubmed	pubmed	PROPN
dti-2192	505	3	74	74	NUM
dti-2192	505	4	.	.	PUNCT
dti-2192	506	1	adeyemo	adeyemo	PROPN
dti-2192	506	2	sm	sm	PROPN
dti-2192	506	3	,	,	PUNCT
dti-2192	506	4	onilude	onilude	VERB
dti-2192	506	5	aa	aa	NOUN
dti-2192	506	6	.	.	PUNCT
dti-2192	507	1	enzymatic	enzymatic	ADJ
dti-2192	507	2	reduction	reduction	NOUN
dti-2192	507	3	of	of	ADP
dti-2192	507	4	antinutritional	antinutritional	ADJ
dti-2192	507	5	factors	factor	NOUN
dti-2192	507	6	in	in	ADP
dti-2192	507	7	fermenting	ferment	VERB
dti-2192	507	8	soybeans	soybean	NOUN
dti-2192	507	9	by	by	ADP
dti-2192	507	10	lactobacillus	lactobacillus	NOUN
dti-2192	507	11	plantarum	plantarum	NOUN
dti-2192	507	12	isolates	isolate	NOUN
dti-2192	507	13	from	from	ADP
dti-2192	507	14	fermenting	ferment	VERB
dti-2192	507	15	cereals	cereal	NOUN
dti-2192	507	16	.	.	PUNCT
dti-2192	508	1	niger	niger	NOUN
dti-2192	508	2	food	food	PROPN
dti-2192	508	3	j.	j.	PROPN
dti-2192	508	4	2013;31(2):84	2013;31(2):84	PROPN
dti-2192	508	5	-	-	SYM
dti-2192	508	6	90	90	NUM
dti-2192	508	7	.	.	PUNCT
dti-2192	509	1	crossref	crossref	PROPN
dti-2192	509	2	75	75	NUM
dti-2192	509	3	.	.	PUNCT
dti-2192	510	1	de	de	PROPN
dti-2192	510	2	blasio	blasio	PROPN
dti-2192	510	3	mj	mj	PROPN
dti-2192	510	4	,	,	PUNCT
dti-2192	510	5	boije	boije	PROPN
dti-2192	510	6	m	m	PROPN
dti-2192	510	7	,	,	PUNCT
dti-2192	510	8	kempster	kempster	PROPN
dti-2192	510	9	sl	sl	PROPN
dti-2192	510	10	,	,	PUNCT
dti-2192	510	11	et	et	PROPN
dti-2192	510	12	al	al	PROPN
dti-2192	510	13	.	.	PROPN
dti-2192	510	14	leptin	leptin	PROPN
dti-2192	510	15	matures	matures	PROPN
dti-2192	510	16	aspects	aspect	NOUN
dti-2192	510	17	of	of	ADP
dti-2192	510	18	lung	lung	NOUN
dti-2192	510	19	structure	structure	NOUN
dti-2192	510	20	and	and	CCONJ
dti-2192	510	21	function	function	NOUN
dti-2192	510	22	in	in	ADP
dti-2192	510	23	the	the	DET
dti-2192	510	24	ovine	ovine	ADJ
dti-2192	510	25	fetus	fetus	NOUN
dti-2192	510	26	.	.	PUNCT
dti-2192	511	1	endocrinology	endocrinology	NOUN
dti-2192	511	2	.	.	PUNCT
dti-2192	512	1	2016;157(1):395	2016;157(1):395	NUM
dti-2192	512	2	-	-	SYM
dti-2192	512	3	404	404	NUM
dti-2192	512	4	.	.	PUNCT
dti-2192	513	1	crossref	crossref	PROPN
dti-2192	513	2	pubmed	pubmed	PROPN
dti-2192	513	3	76	76	NUM
dti-2192	513	4	.	.	PUNCT
dti-2192	514	1	torday	torday	PROPN
dti-2192	514	2	js	js	PROPN
dti-2192	514	3	,	,	PUNCT
dti-2192	514	4	powell	powell	PROPN
dti-2192	514	5	fl	fl	PROPN
dti-2192	514	6	,	,	PUNCT
dti-2192	514	7	farmer	farmer	NOUN
dti-2192	514	8	cg	cg	NOUN
dti-2192	514	9	,	,	PUNCT
dti-2192	514	10	orgeig	orgeig	NOUN
dti-2192	514	11	s	s	PART
dti-2192	514	12	,	,	PUNCT
dti-2192	514	13	nielsen	nielsen	PROPN
dti-2192	514	14	hc	hc	PROPN
dti-2192	514	15	,	,	PUNCT
dti-2192	514	16	hall	hall	PROPN
dti-2192	514	17	aj	aj	PROPN
dti-2192	514	18	.	.	PROPN
dti-2192	514	19	leptin	leptin	PROPN
dti-2192	514	20	integrates	integrate	NOUN
dti-2192	514	21	vertebrate	vertebrate	ADJ
dti-2192	514	22	evolution	evolution	NOUN
dti-2192	514	23	:	:	PUNCT
dti-2192	514	24	from	from	ADP
dti-2192	514	25	oxygen	oxygen	NOUN
dti-2192	514	26	to	to	ADP
dti-2192	514	27	the	the	DET
dti-2192	514	28	blood	blood	NOUN
dti-2192	514	29	-	-	PUNCT
dti-2192	514	30	gas	gas	NOUN
dti-2192	514	31	barrier	barrier	NOUN
dti-2192	514	32	.	.	PUNCT
dti-2192	515	1	respir	respir	VERB
dti-2192	515	2	physiol	physiol	PROPN
dti-2192	515	3	neurobiol	neurobiol	PROPN
dti-2192	515	4	.	.	PUNCT
dti-2192	516	1	2010;173(1	2010;173(1	X
dti-2192	516	2	)	)	PUNCT
dti-2192	516	3	(	(	PUNCT
dti-2192	516	4	suppl):s37	suppl):s37	PROPN
dti-2192	516	5	-	-	PUNCT
dti-2192	516	6	s42	s42	NOUN
dti-2192	516	7	.	.	PUNCT
dti-2192	517	1	crossref	crossref	PROPN
dti-2192	517	2	pubmed	pubmed	PROPN
dti-2192	517	3	77	77	NUM
dti-2192	517	4	.	.	PUNCT
dti-2192	518	1	bassi	bassi	PROPN
dti-2192	518	2	m	m	PROPN
dti-2192	518	3	,	,	PUNCT
dti-2192	518	4	furuya	furuya	PROPN
dti-2192	518	5	wi	wi	PROPN
dti-2192	518	6	,	,	PUNCT
dti-2192	518	7	menani	menani	PROPN
dti-2192	518	8	jv	jv	PROPN
dti-2192	518	9	,	,	PUNCT
dti-2192	518	10	et	et	PROPN
dti-2192	518	11	al	al	PROPN
dti-2192	518	12	.	.	PROPN
dti-2192	518	13	leptin	leptin	PROPN
dti-2192	518	14	into	into	ADP
dti-2192	518	15	the	the	DET
dti-2192	518	16	ventrolateral	ventrolateral	ADJ
dti-2192	518	17	medulla	medulla	NOUN
dti-2192	518	18	facilitates	facilitate	VERB
dti-2192	518	19	chemorespiratory	chemorespiratory	ADJ
dti-2192	518	20	response	response	NOUN
dti-2192	518	21	in	in	ADP
dti-2192	518	22	leptin	leptin	NOUN
dti-2192	518	23	-	-	PUNCT
dti-2192	518	24	deficient	deficient	ADJ
dti-2192	518	25	(	(	PUNCT
dti-2192	518	26	ob	ob	NOUN
dti-2192	518	27	/	/	SYM
dti-2192	518	28	ob	ob	NOUN
dti-2192	518	29	)	)	PUNCT
dti-2192	518	30	mice	mouse	NOUN
dti-2192	518	31	.	.	PUNCT
dti-2192	519	1	acta	acta	PROPN
dti-2192	519	2	physiol	physiol	PROPN
dti-2192	519	3	(	(	PUNCT
dti-2192	519	4	oxf	oxf	PROPN
dti-2192	519	5	)	)	PUNCT
dti-2192	519	6	.	.	PUNCT
dti-2192	520	1	2014;211(1	2014;211(1	X
dti-2192	520	2	):	):	PUNCT
dti-2192	520	3	240	240	NUM
dti-2192	520	4	-	-	SYM
dti-2192	520	5	248	248	NUM
dti-2192	520	6	.	.	PUNCT
dti-2192	521	1	crossref	crossref	PROPN
dti-2192	521	2	pubmed	pubmed	PROPN
dti-2192	521	3	78	78	NUM
dti-2192	521	4	.	.	PUNCT
dti-2192	522	1	sideleva	sideleva	PROPN
dti-2192	522	2	o	o	PROPN
dti-2192	522	3	,	,	PUNCT
dti-2192	522	4	dixon	dixon	PROPN
dti-2192	522	5	ae	ae	PROPN
dti-2192	522	6	.	.	PUNCT
dti-2192	523	1	the	the	DET
dti-2192	523	2	many	many	ADJ
dti-2192	523	3	faces	face	NOUN
dti-2192	523	4	of	of	ADP
dti-2192	523	5	asthma	asthma	NOUN
dti-2192	523	6	in	in	ADP
dti-2192	523	7	obesity	obesity	NOUN
dti-2192	523	8	.	.	PUNCT
dti-2192	524	1	j	j	PROPN
dti-2192	524	2	cell	cell	PROPN
dti-2192	524	3	biochem	biochem	PROPN
dti-2192	524	4	.	.	PUNCT
dti-2192	525	1	2014;115(3):421	2014;115(3):421	NUM
dti-2192	525	2	-	-	SYM
dti-2192	525	3	426	426	NUM
dti-2192	525	4	.	.	PUNCT
dti-2192	526	1	crossref	crossref	PROPN
dti-2192	526	2	pubmed	pubmed	PROPN
dti-2192	526	3	79	79	NUM
dti-2192	526	4	.	.	PUNCT
dti-2192	527	1	sood	sood	PROPN
dti-2192	527	2	a	a	PRON
dti-2192	527	3	,	,	PUNCT
dti-2192	527	4	ford	ford	PROPN
dti-2192	527	5	es	es	PROPN
dti-2192	527	6	,	,	PUNCT
dti-2192	527	7	camargo	camargo	PROPN
dti-2192	527	8	ca	ca	PROPN
dti-2192	527	9	jr	jr	PROPN
dti-2192	527	10	.	.	PROPN
dti-2192	527	11	association	association	PROPN
dti-2192	527	12	between	between	ADP
dti-2192	527	13	leptin	leptin	NOUN
dti-2192	527	14	and	and	CCONJ
dti-2192	527	15	asthma	asthma	NOUN
dti-2192	527	16	in	in	ADP
dti-2192	527	17	adults	adult	NOUN
dti-2192	527	18	.	.	PUNCT
dti-2192	528	1	thorax	thorax	NOUN
dti-2192	528	2	.	.	PUNCT
dti-2192	529	1	2006;61(4):300	2006;61(4):300	NUM
dti-2192	529	2	-	-	SYM
dti-2192	529	3	305	305	NUM
dti-2192	529	4	.	.	PUNCT
dti-2192	530	1	crossref	crossref	PROPN
dti-2192	530	2	pubmed	pubmed	PROPN
dti-2192	530	3	80	80	NUM
dti-2192	530	4	.	.	PUNCT
dti-2192	531	1	fook	fook	PROPN
dti-2192	531	2	jmsll	jmsll	PROPN
dti-2192	531	3	,	,	PUNCT
dti-2192	531	4	macedo	macedo	PROPN
dti-2192	531	5	llp	llp	PROPN
dti-2192	531	6	,	,	PUNCT
dti-2192	531	7	moura	moura	PROPN
dti-2192	531	8	gedd	gedd	PROPN
dti-2192	531	9	,	,	PUNCT
dti-2192	531	10	et	et	PROPN
dti-2192	531	11	al	al	PROPN
dti-2192	531	12	.	.	PUNCT
dti-2192	532	1	a	a	DET
dti-2192	532	2	serine	serine	ADJ
dti-2192	532	3	proteinase	proteinase	NOUN
dti-2192	532	4	inhibitor	inhibitor	NOUN
dti-2192	532	5	isolated	isolate	VERB
dti-2192	532	6	from	from	ADP
dti-2192	532	7	tamarindus	tamarindus	NOUN
dti-2192	532	8	indica	indica	ADJ
dti-2192	532	9	seeds	seed	NOUN
dti-2192	532	10	and	and	CCONJ
dti-2192	532	11	its	its	PRON
dti-2192	532	12	effects	effect	NOUN
dti-2192	532	13	on	on	ADP
dti-2192	532	14	the	the	DET
dti-2192	532	15	release	release	NOUN
dti-2192	532	16	of	of	ADP
dti-2192	532	17	human	human	ADJ
dti-2192	532	18	neutrophil	neutrophil	ADJ
dti-2192	532	19	elastase	elastase	NOUN
dti-2192	532	20	.	.	PUNCT
dti-2192	533	1	life	life	PROPN
dti-2192	533	2	sci	sci	PROPN
dti-2192	533	3	.	.	PUNCT
dti-2192	534	1	2005;76(25):2881	2005;76(25):2881	NUM
dti-2192	534	2	-	-	SYM
dti-2192	534	3	2891	2891	NUM
dti-2192	534	4	.	.	PUNCT
dti-2192	535	1	crossref	crossref	PROPN
dti-2192	535	2	pubmed	pubmed	PROPN
dti-2192	535	3	81	81	NUM
dti-2192	535	4	.	.	PUNCT
dti-2192	536	1	ribeiro	ribeiro	PROPN
dti-2192	536	2	jkc	jkc	PROPN
dti-2192	536	3	,	,	PUNCT
dti-2192	536	4	cunha	cunha	PROPN
dti-2192	536	5	dds	dds	PROPN
dti-2192	536	6	,	,	PUNCT
dti-2192	536	7	fook	fook	NOUN
dti-2192	536	8	jmsll	jmsll	PROPN
dti-2192	536	9	,	,	PUNCT
dti-2192	536	10	sales	sales	PROPN
dti-2192	536	11	mp	mp	PROPN
dti-2192	536	12	.	.	PUNCT
dti-2192	537	1	new	new	ADJ
dti-2192	537	2	properties	property	NOUN
dti-2192	537	3	of	of	ADP
dti-2192	537	4	the	the	DET
dti-2192	537	5	soybean	soybean	NOUN
dti-2192	537	6	trypsin	trypsin	NOUN
dti-2192	537	7	inhibitor	inhibitor	NOUN
dti-2192	537	8	:	:	PUNCT
dti-2192	537	9	inhibition	inhibition	NOUN
dti-2192	537	10	of	of	ADP
dti-2192	537	11	human	human	ADJ
dti-2192	537	12	neutrophil	neutrophil	ADJ
dti-2192	537	13	elastase	elastase	NOUN
dti-2192	537	14	and	and	CCONJ
dti-2192	537	15	its	its	PRON
dti-2192	537	16	effect	effect	NOUN
dti-2192	537	17	on	on	ADP
dti-2192	537	18	acute	acute	ADJ
dti-2192	537	19	pulmonary	pulmonary	ADJ
dti-2192	537	20	injury	injury	NOUN
dti-2192	537	21	.	.	PUNCT
dti-2192	538	1	eur	eur	PROPN
dti-2192	538	2	j	j	PROPN
dti-2192	538	3	pharmacol	pharmacol	PROPN
dti-2192	538	4	.	.	PUNCT
dti-2192	539	1	2010;644(1	2010;644(1	NUM
dti-2192	539	2	-	-	PUNCT
dti-2192	539	3	3):238	3):238	PROPN
dti-2192	539	4	-	-	PUNCT
dti-2192	539	5	244	244	NUM
dti-2192	539	6	.	.	PUNCT
dti-2192	540	1	crossref	crossref	PROPN
dti-2192	540	2	pubmed	pubmed	PROPN
dti-2192	540	3	82	82	NUM
dti-2192	540	4	.	.	PUNCT
dti-2192	541	1	thanigaimalai	thanigaimalai	PROPN
dti-2192	541	2	p	p	X
dti-2192	541	3	,	,	PUNCT
dti-2192	541	4	konno	konno	NOUN
dti-2192	541	5	s	s	PROPN
dti-2192	541	6	,	,	PUNCT
dti-2192	541	7	yamamoto	yamamoto	PROPN
dti-2192	541	8	t	t	PROPN
dti-2192	541	9	,	,	PUNCT
dti-2192	541	10	et	et	PROPN
dti-2192	541	11	al	al	PROPN
dti-2192	541	12	.	.	PUNCT
dti-2192	541	13	development	development	NOUN
dti-2192	541	14	of	of	ADP
dti-2192	541	15	potent	potent	ADJ
dti-2192	541	16	dipeptide	dipeptide	NOUN
dti-2192	541	17	-	-	PUNCT
dti-2192	541	18	type	type	NOUN
dti-2192	541	19	sars	sar	NOUN
dti-2192	541	20	-	-	PUNCT
dti-2192	541	21	cov	cov	NOUN
dti-2192	541	22	3cl	3cl	ADJ
dti-2192	541	23	protease	protease	NOUN
dti-2192	541	24	inhibitors	inhibitor	NOUN
dti-2192	541	25	with	with	ADP
dti-2192	541	26	novel	novel	ADJ
dti-2192	541	27	p3	p3	NOUN
dti-2192	541	28	scaffolds	scaffold	NOUN
dti-2192	541	29	:	:	PUNCT
dti-2192	541	30	design	design	NOUN
dti-2192	541	31	,	,	PUNCT
dti-2192	541	32	synthesis	synthesis	NOUN
dti-2192	541	33	,	,	PUNCT
dti-2192	541	34	biological	biological	ADJ
dti-2192	541	35	evaluation	evaluation	NOUN
dti-2192	541	36	,	,	PUNCT
dti-2192	541	37	and	and	CCONJ
dti-2192	541	38	docking	dock	VERB
dti-2192	541	39	studies	study	NOUN
dti-2192	541	40	.	.	PUNCT
dti-2192	542	1	eur	eur	PROPN
dti-2192	542	2	j	j	PROPN
dti-2192	542	3	med	med	PROPN
dti-2192	542	4	chem	chem	NOUN
dti-2192	542	5	.	.	PUNCT
dti-2192	543	1	2013;68:372	2013;68:372	VERB
dti-2192	543	2	-	-	SYM
dti-2192	543	3	384	384	NUM
dti-2192	543	4	.	.	PUNCT
dti-2192	544	1	crossref	crossref	PROPN
dti-2192	544	2	pubmed	pubmed	PROPN
dti-2192	544	3	83	83	NUM
dti-2192	544	4	.	.	PUNCT
dti-2192	545	1	elfiky	elfiky	VERB
dti-2192	545	2	aa	aa	PROPN
dti-2192	545	3	.	.	PUNCT
dti-2192	546	1	ribavirin	ribavirin	NOUN
dti-2192	546	2	,	,	PUNCT
dti-2192	546	3	remdesivir	remdesivir	PROPN
dti-2192	546	4	,	,	PUNCT
dti-2192	546	5	sofosbuvir	sofosbuvir	PROPN
dti-2192	546	6	,	,	PUNCT
dti-2192	546	7	galidesivir	galidesivir	PROPN
dti-2192	546	8	,	,	PUNCT
dti-2192	546	9	and	and	CCONJ
dti-2192	546	10	tenofovir	tenofovir	NOUN
dti-2192	546	11	against	against	ADP
dti-2192	546	12	sars	sar	NOUN
dti-2192	546	13	-	-	PUNCT
dti-2192	546	14	cov-2	cov-2	NOUN
dti-2192	546	15	rna	rna	NOUN
dti-2192	546	16	dependent	dependent	ADJ
dti-2192	546	17	rna	rna	NOUN
dti-2192	546	18	polymerase	polymerase	NOUN
dti-2192	546	19	(	(	PUNCT
dti-2192	546	20	rdrp	rdrp	PROPN
dti-2192	546	21	):	):	PUNCT
dti-2192	546	22	a	a	DET
dti-2192	546	23	molecular	molecular	ADJ
dti-2192	546	24	docking	docking	NOUN
dti-2192	546	25	study	study	NOUN
dti-2192	546	26	.	.	PUNCT
dti-2192	547	1	life	life	PROPN
dti-2192	547	2	sci	sci	PROPN
dti-2192	547	3	.	.	PUNCT
dti-2192	548	1	2020;253(february):117592	2020;253(february):117592	NUM
dti-2192	548	2	.	.	PUNCT
dti-2192	549	1	crossref	crossref	PROPN
dti-2192	549	2	pubmed	pubmed	PROPN
dti-2192	549	3	84	84	NUM
dti-2192	549	4	.	.	PUNCT
dti-2192	550	1	wu	wu	PROPN
dti-2192	550	2	c	c	PROPN
dti-2192	550	3	,	,	PUNCT
dti-2192	550	4	liu	liu	PROPN
dti-2192	550	5	y	y	PROPN
dti-2192	550	6	,	,	PUNCT
dti-2192	550	7	yang	yang	PROPN
dti-2192	550	8	y	y	PROPN
dti-2192	550	9	,	,	PUNCT
dti-2192	550	10	et	et	PROPN
dti-2192	550	11	al	al	PROPN
dti-2192	550	12	.	.	PUNCT
dti-2192	551	1	analysis	analysis	NOUN
dti-2192	551	2	of	of	ADP
dti-2192	551	3	therapeutic	therapeutic	ADJ
dti-2192	551	4	targets	target	NOUN
dti-2192	551	5	for	for	ADP
dti-2192	551	6	sarscov-2	sarscov-2	NUM
dti-2192	551	7	and	and	CCONJ
dti-2192	551	8	discovery	discovery	NOUN
dti-2192	551	9	of	of	ADP
dti-2192	551	10	potential	potential	ADJ
dti-2192	551	11	drugs	drug	NOUN
dti-2192	551	12	by	by	ADP
dti-2192	551	13	computational	computational	ADJ
dti-2192	551	14	methods	method	NOUN
dti-2192	551	15	.	.	PUNCT
dti-2192	552	1	acta	acta	PROPN
dti-2192	552	2	pharm	pharm	PROPN
dti-2192	552	3	sin	sin	PROPN
dti-2192	552	4	b.	b.	PROPN
dti-2192	552	5	2020;10(5):766	2020;10(5):766	PROPN
dti-2192	552	6	-	-	NUM
dti-2192	552	7	788	788	NUM
dti-2192	552	8	.	.	PUNCT
dti-2192	553	1	crossref	crossref	PROPN
dti-2192	553	2	pubmed	pubmed	PROPN
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dti-2192	553	7	https://www.ncbi.nlm.nih.gov/pubmed/6996568	https://www.ncbi.nlm.nih.gov/pubmed/6996568	PRON
dti-2192	553	8	https://doi.org/10.1007/s11356-018-4007-6	https://doi.org/10.1007/s11356-018-4007-6	NUM
dti-2192	553	9	https://www.ncbi.nlm.nih.gov/pubmed/30612348	https://www.ncbi.nlm.nih.gov/pubmed/30612348	NUM
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dti-2192	553	27	https://www.ncbi.nlm.nih.gov/pubmed/31739532	https://www.ncbi.nlm.nih.gov/pubmed/31739532	NUM
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dti-2192	554	1	https://doi.org/10.1002/jcb.24678	https://doi.org/10.1002/jcb.24678	PROPN
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dti-2192	555	1	https://doi.org/10.1016/j.lfs.2004.10.053	https://doi.org/10.1016/j.lfs.2004.10.053	PROPN
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dti-2192	557	1	https://www.ncbi.nlm.nih.gov/pubmed/20624384	https://www.ncbi.nlm.nih.gov/pubmed/20624384	NUM
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dti-2192	557	4	https://doi.org/10.1016/j.lfs.2020.117592	https://doi.org/10.1016/j.lfs.2020.117592	X
dti-2192	557	5	https://www.ncbi.nlm.nih.gov/pubmed/32222463	https://www.ncbi.nlm.nih.gov/pubmed/32222463	PRON
dti-2192	557	6	https://doi.org/10.1016/j.apsb.2020.02.008	https://doi.org/10.1016/j.apsb.2020.02.008	PROPN
dti-2192	557	7	https://www.ncbi.nlm.nih.gov/pubmed/32292689	https://www.ncbi.nlm.nih.gov/pubmed/32292689	NUM