id	sid	tid	token	lemma	pos
dti-2277	1	1	untitled	untitled	ADJ
dti-2277	1	2	9	9	NUM
dti-2277	1	3	correspondence	correspondence	NOUN
dti-2277	1	4	:	:	PUNCT
dti-2277	1	5	kunitada	kunitada	PROPN
dti-2277	1	6	shimotohno	shimotohno	NOUN
dti-2277	1	7	,	,	PUNCT
dti-2277	1	8	ph	ph	PROPN
dti-2277	1	9	.	.	PROPN
dti-2277	1	10	d.	d.	PROPN
dti-2277	1	11	,	,	PUNCT
dti-2277	1	12	laboratory	laboratory	NOUN
dti-2277	1	13	of	of	ADP
dti-2277	1	14	human	human	ADJ
dti-2277	1	15	tumor	tumor	NOUN
dti-2277	1	16	viruses	virus	NOUN
dti-2277	1	17	,	,	PUNCT
dti-2277	1	18	institute	institute	NOUN
dti-2277	1	19	for	for	ADP
dti-2277	1	20	virus	virus	NOUN
dti-2277	1	21	research	research	PROPN
dti-2277	1	22	,	,	PUNCT
dti-2277	1	23	kyoto	kyoto	PROPN
dti-2277	1	24	university	university	PROPN
dti-2277	1	25	,	,	PUNCT
dti-2277	1	26	53	53	NUM
dti-2277	1	27	kawaharacho	kawaharacho	NOUN
dti-2277	1	28	,	,	PUNCT
dti-2277	1	29	shogoin	shogoin	PROPN
dti-2277	1	30	,	,	PUNCT
dti-2277	1	31	sakyo	sakyo	PROPN
dti-2277	1	32	-	-	PUNCT
dti-2277	1	33	ku	ku	PROPN
dti-2277	1	34	,	,	PUNCT
dti-2277	1	35	kyoto	kyoto	PROPN
dti-2277	1	36	,	,	PUNCT
dti-2277	1	37	606	606	NUM
dti-2277	1	38	-	-	SYM
dti-2277	1	39	8507	8507	NUM
dti-2277	1	40	,	,	PUNCT
dti-2277	1	41	japan	japan	PROPN
dti-2277	1	42	.	.	PUNCT
dti-2277	2	1	tel	tel	ADP
dti-2277	2	2	:	:	PUNCT
dti-2277	2	3	+81	+81	NUM
dti-2277	2	4	-	-	PUNCT
dti-2277	2	5	75	75	NUM
dti-2277	2	6	-	-	PUNCT
dti-2277	2	7	751	751	NUM
dti-2277	2	8	-	-	SYM
dti-2277	2	9	4000	4000	NUM
dti-2277	2	10	;	;	PUNCT
dti-2277	2	11	fax	fax	NOUN
dti-2277	2	12	:	:	PUNCT
dti-2277	2	13	+81	+81	NUM
dti-2277	2	14	-	-	PUNCT
dti-2277	2	15	75	75	NUM
dti-2277	2	16	-	-	PUNCT
dti-2277	2	17	751	751	NUM
dti-2277	2	18	-	-	SYM
dti-2277	2	19	3998	3998	NUM
dti-2277	2	20	;	;	PUNCT
dti-2277	2	21	email	email	NOUN
dti-2277	2	22	:	:	PUNCT
dti-2277	2	23	kshimoto@virus.kyoto-u.ac.jp	kshimoto@virus.kyoto-u.ac.jp	PRON
dti-2277	2	24	please	please	INTJ
dti-2277	2	25	note	note	VERB
dti-2277	2	26	that	that	SCONJ
dti-2277	2	27	this	this	DET
dti-2277	2	28	article	article	NOUN
dti-2277	2	29	may	may	AUX
dti-2277	2	30	not	not	PART
dti-2277	2	31	be	be	AUX
dti-2277	2	32	used	use	VERB
dti-2277	2	33	for	for	ADP
dti-2277	2	34	commercial	commercial	ADJ
dti-2277	2	35	purposes	purpose	NOUN
dti-2277	2	36	.	.	PUNCT
dti-2277	3	1	for	for	ADP
dti-2277	3	2	further	further	ADJ
dti-2277	3	3	information	information	NOUN
dti-2277	3	4	please	please	INTJ
dti-2277	3	5	refer	refer	VERB
dti-2277	3	6	to	to	ADP
dti-2277	3	7	the	the	DET
dti-2277	3	8	copyright	copyright	NOUN
dti-2277	3	9	statement	statement	NOUN
dti-2277	3	10	at	at	ADP
dti-2277	3	11	http://www.la-press.com/copyright.htm	http://www.la-press.com/copyright.htm	PROPN
dti-2277	3	12	review	review	NOUN
dti-2277	3	13	cyclophilin	cyclophilin	PROPN
dti-2277	3	14	and	and	CCONJ
dti-2277	3	15	viruses	virus	NOUN
dti-2277	3	16	:	:	PUNCT
dti-2277	3	17	cyclophilin	cyclophilin	PROPN
dti-2277	3	18	as	as	ADP
dti-2277	3	19	a	a	DET
dti-2277	3	20	cofactor	cofactor	NOUN
dti-2277	3	21	for	for	ADP
dti-2277	3	22	viral	viral	ADJ
dti-2277	3	23	infection	infection	NOUN
dti-2277	3	24	and	and	CCONJ
dti-2277	3	25	possible	possible	ADJ
dti-2277	3	26	anti	anti	ADJ
dti-2277	3	27	-	-	ADJ
dti-2277	3	28	viral	viral	ADJ
dti-2277	3	29	target	target	NOUN
dti-2277	3	30	koichi	koichi	PROPN
dti-2277	3	31	watashi	watashi	PROPN
dti-2277	3	32	and	and	CCONJ
dti-2277	3	33	kunitada	kunitada	PROPN
dti-2277	3	34	shimotohno	shimotohno	PROPN
dti-2277	3	35	department	department	PROPN
dti-2277	3	36	of	of	ADP
dti-2277	3	37	viral	viral	ADJ
dti-2277	3	38	oncology	oncology	NOUN
dti-2277	3	39	,	,	PUNCT
dti-2277	3	40	institute	institute	NOUN
dti-2277	3	41	for	for	ADP
dti-2277	3	42	virus	virus	NOUN
dti-2277	3	43	research	research	PROPN
dti-2277	3	44	,	,	PUNCT
dti-2277	3	45	kyoto	kyoto	PROPN
dti-2277	3	46	university	university	PROPN
dti-2277	3	47	,	,	PUNCT
dti-2277	3	48	kyoto	kyoto	PROPN
dti-2277	3	49	,	,	PUNCT
dti-2277	3	50	japan	japan	PROPN
dti-2277	3	51	.	.	PUNCT
dti-2277	4	1	abstract	abstract	PROPN
dti-2277	4	2	:	:	PUNCT
dti-2277	4	3	cyclophilin	cyclophilin	PROPN
dti-2277	4	4	(	(	PUNCT
dti-2277	4	5	cyp	cyp	ADJ
dti-2277	4	6	)	)	PUNCT
dti-2277	4	7	is	be	AUX
dti-2277	4	8	a	a	DET
dti-2277	4	9	peptidyl	peptidyl	NOUN
dti-2277	4	10	prolyl	prolyl	NOUN
dti-2277	4	11	cis	cis	NOUN
dti-2277	4	12	/	/	SYM
dti-2277	4	13	trans	trans	X
dti-2277	4	14	isomerase	isomerase	NOUN
dti-2277	4	15	,	,	PUNCT
dti-2277	4	16	catalyzing	catalyze	VERB
dti-2277	4	17	the	the	DET
dti-2277	4	18	cis	cis	NOUN
dti-2277	4	19	-	-	PUNCT
dti-2277	4	20	trans	trans	ADJ
dti-2277	4	21	isomerization	isomerization	NOUN
dti-2277	4	22	of	of	ADP
dti-2277	4	23	proline	proline	NOUN
dti-2277	4	24	residues	residue	NOUN
dti-2277	4	25	in	in	ADP
dti-2277	4	26	proteins	protein	NOUN
dti-2277	4	27	.	.	PUNCT
dti-2277	5	1	cyp	cyp	ADJ
dti-2277	5	2	plays	play	VERB
dti-2277	5	3	key	key	ADJ
dti-2277	5	4	roles	role	NOUN
dti-2277	5	5	in	in	ADP
dti-2277	5	6	several	several	ADJ
dti-2277	5	7	different	different	ADJ
dti-2277	5	8	aspects	aspect	NOUN
dti-2277	5	9	of	of	ADP
dti-2277	5	10	cellular	cellular	ADJ
dti-2277	5	11	physiology	physiology	NOUN
dti-2277	5	12	including	include	VERB
dti-2277	5	13	the	the	DET
dti-2277	5	14	immune	immune	ADJ
dti-2277	5	15	response	response	NOUN
dti-2277	5	16	,	,	PUNCT
dti-2277	5	17	transcription	transcription	NOUN
dti-2277	5	18	,	,	PUNCT
dti-2277	5	19	mitochondrial	mitochondrial	ADJ
dti-2277	5	20	function	function	NOUN
dti-2277	5	21	,	,	PUNCT
dti-2277	5	22	cell	cell	NOUN
dti-2277	5	23	death	death	NOUN
dti-2277	5	24	,	,	PUNCT
dti-2277	5	25	and	and	CCONJ
dti-2277	5	26	chemotaxis	chemotaxis	ADJ
dti-2277	5	27	.	.	PUNCT
dti-2277	6	1	in	in	ADP
dti-2277	6	2	addition	addition	NOUN
dti-2277	6	3	to	to	ADP
dti-2277	6	4	these	these	DET
dti-2277	6	5	cellular	cellular	ADJ
dti-2277	6	6	events	event	NOUN
dti-2277	6	7	,	,	PUNCT
dti-2277	6	8	a	a	DET
dti-2277	6	9	number	number	NOUN
dti-2277	6	10	of	of	ADP
dti-2277	6	11	reports	report	NOUN
dti-2277	6	12	demonstrated	demonstrate	VERB
dti-2277	6	13	that	that	SCONJ
dti-2277	6	14	cyp	cyp	ADJ
dti-2277	6	15	plays	play	VERB
dti-2277	6	16	a	a	DET
dti-2277	6	17	critical	critical	ADJ
dti-2277	6	18	role	role	NOUN
dti-2277	6	19	in	in	ADP
dti-2277	6	20	the	the	DET
dti-2277	6	21	life	life	NOUN
dti-2277	6	22	cycle	cycle	NOUN
dti-2277	6	23	of	of	ADP
dti-2277	6	24	viruses	virus	NOUN
dti-2277	6	25	,	,	PUNCT
dti-2277	6	26	especially	especially	ADV
dti-2277	6	27	human	human	ADJ
dti-2277	6	28	immunodefi	immunodefi	ADJ
dti-2277	6	29	ciency	ciency	NOUN
dti-2277	6	30	virus	virus	NOUN
dti-2277	6	31	(	(	PUNCT
dti-2277	6	32	hiv	hiv	PROPN
dti-2277	6	33	)	)	PUNCT
dti-2277	6	34	and	and	CCONJ
dti-2277	6	35	hepatitis	hepatitis	PROPN
dti-2277	6	36	c	c	PROPN
dti-2277	6	37	virus	virus	NOUN
dti-2277	6	38	(	(	PUNCT
dti-2277	6	39	hcv	hcv	PROPN
dti-2277	6	40	)	)	PUNCT
dti-2277	6	41	.	.	PUNCT
dti-2277	7	1	these	these	DET
dti-2277	7	2	two	two	NUM
dti-2277	7	3	viruses	virus	NOUN
dti-2277	7	4	are	be	AUX
dti-2277	7	5	signifi	signifi	NOUN
dti-2277	7	6	ca	can	AUX
dti-2277	7	7	nt	not	PART
dti-2277	7	8	causes	cause	NOUN
dti-2277	7	9	of	of	ADP
dti-2277	7	10	morbidity	morbidity	NOUN
dti-2277	7	11	and	and	CCONJ
dti-2277	7	12	mortality	mortality	NOUN
dti-2277	7	13	worldwide	worldwide	ADV
dti-2277	7	14	,	,	PUNCT
dti-2277	7	15	but	but	CCONJ
dti-2277	7	16	current	current	ADJ
dti-2277	7	17	therapies	therapy	NOUN
dti-2277	7	18	are	be	AUX
dti-2277	7	19	often	often	ADV
dti-2277	7	20	insuffi	insuffi	ADJ
dti-2277	7	21	cient	cient	NOUN
dti-2277	7	22	.	.	PUNCT
dti-2277	8	1	cyp	cyp	PROPN
dti-2277	8	2	may	may	AUX
dti-2277	8	3	provide	provide	VERB
dti-2277	8	4	a	a	DET
dti-2277	8	5	novel	novel	ADJ
dti-2277	8	6	therapeutic	therapeutic	ADJ
dti-2277	8	7	target	target	NOUN
dti-2277	8	8	for	for	ADP
dti-2277	8	9	the	the	DET
dti-2277	8	10	management	management	NOUN
dti-2277	8	11	and/or	and/or	CCONJ
dti-2277	8	12	cure	cure	NOUN
dti-2277	8	13	of	of	ADP
dti-2277	8	14	these	these	DET
dti-2277	8	15	diseases	disease	NOUN
dti-2277	8	16	,	,	PUNCT
dti-2277	8	17	in	in	ADP
dti-2277	8	18	particular	particular	ADJ
dti-2277	8	19	hcv	hcv	NOUN
dti-2277	8	20	.	.	PUNCT
dti-2277	9	1	keywords	keyword	NOUN
dti-2277	9	2	:	:	PUNCT
dti-2277	9	3	cyclosporin	cyclosporin	NOUN
dti-2277	9	4	,	,	PUNCT
dti-2277	9	5	hiv	hiv	PROPN
dti-2277	9	6	,	,	PUNCT
dti-2277	9	7	hcv	hcv	PROPN
dti-2277	9	8	,	,	PUNCT
dti-2277	9	9	virus	virus	NOUN
dti-2277	9	10	,	,	PUNCT
dti-2277	9	11	replication	replication	NOUN
dti-2277	9	12	,	,	PUNCT
dti-2277	9	13	mptp	mptp	PROPN
dti-2277	9	14	.	.	PUNCT
dti-2277	10	1	immunophilins	immunophilin	NOUN
dti-2277	10	2	and	and	CCONJ
dti-2277	10	3	immunosuppressants	immunosuppressant	NOUN
dti-2277	10	4	cyclophilin	cyclophilin	PROPN
dti-2277	10	5	(	(	PUNCT
dti-2277	10	6	cyp	cyp	ADJ
dti-2277	10	7	)	)	PUNCT
dti-2277	10	8	and	and	CCONJ
dti-2277	10	9	fk506	fk506	NOUN
dti-2277	10	10	binding	bind	VERB
dti-2277	10	11	protein	protein	NOUN
dti-2277	10	12	(	(	PUNCT
dti-2277	10	13	fkbp	fkbp	NOUN
dti-2277	10	14	)	)	PUNCT
dti-2277	10	15	are	be	AUX
dti-2277	10	16	peptidyl	peptidyl	NOUN
dti-2277	10	17	-	-	PUNCT
dti-2277	10	18	prolyl	prolyl	NOUN
dti-2277	10	19	cis	cis	NOUN
dti-2277	10	20	-	-	PUNCT
dti-2277	10	21	trans	trans	ADJ
dti-2277	10	22	isomerases	isomerase	NOUN
dti-2277	10	23	(	(	PUNCT
dti-2277	10	24	ppiases	ppiase	NOUN
dti-2277	10	25	)	)	PUNCT
dti-2277	10	26	,	,	PUNCT
dti-2277	10	27	enzymes	enzyme	NOUN
dti-2277	10	28	that	that	PRON
dti-2277	10	29	catalyze	catalyze	VERB
dti-2277	10	30	the	the	DET
dti-2277	10	31	cis	cis	NOUN
dti-2277	10	32	-	-	PUNCT
dti-2277	10	33	trans	trans	ADJ
dti-2277	10	34	interconversion	interconversion	NOUN
dti-2277	10	35	of	of	ADP
dti-2277	10	36	peptide	peptide	ADJ
dti-2277	10	37	bonds	bond	NOUN
dti-2277	10	38	amino	amino	NOUN
dti-2277	10	39	terminal	terminal	NOUN
dti-2277	10	40	to	to	ADP
dti-2277	10	41	proline	proline	NOUN
dti-2277	10	42	residues	residue	NOUN
dti-2277	10	43	(	(	PUNCT
dti-2277	10	44	fischer	fischer	PROPN
dti-2277	10	45	et	et	PROPN
dti-2277	10	46	al	al	PROPN
dti-2277	10	47	.	.	PROPN
dti-2277	10	48	1989	1989	NUM
dti-2277	10	49	;	;	PUNCT
dti-2277	11	1	harding	harding	PROPN
dti-2277	11	2	et	et	PROPN
dti-2277	11	3	al	al	PROPN
dti-2277	11	4	.	.	PROPN
dti-2277	11	5	1989	1989	NUM
dti-2277	11	6	;	;	PUNCT
dti-2277	11	7	takahashi	takahashi	PROPN
dti-2277	11	8	,	,	PUNCT
dti-2277	11	9	1999	1999	NUM
dti-2277	11	10	;	;	PUNCT
dti-2277	11	11	takahashi	takahashi	PROPN
dti-2277	11	12	et	et	PROPN
dti-2277	11	13	al	al	PROPN
dti-2277	11	14	.	.	PROPN
dti-2277	11	15	1989	1989	NUM
dti-2277	11	16	)	)	PUNCT
dti-2277	11	17	.	.	PUNCT
dti-2277	12	1	cyp	cyp	ADJ
dti-2277	12	2	and	and	CCONJ
dti-2277	12	3	fkbp	fkbp	NOUN
dti-2277	12	4	are	be	AUX
dti-2277	12	5	originally	originally	ADV
dti-2277	12	6	identifi	identifi	NOUN
dti-2277	12	7	ed	ed	NOUN
dti-2277	12	8	as	as	ADP
dti-2277	12	9	cellular	cellular	ADJ
dti-2277	12	10	factors	factor	NOUN
dti-2277	12	11	that	that	PRON
dti-2277	12	12	bind	bind	VERB
dti-2277	12	13	csa	csa	PROPN
dti-2277	12	14	and	and	CCONJ
dti-2277	12	15	fk506	fk506	PROPN
dti-2277	12	16	,	,	PUNCT
dti-2277	12	17	respectively	respectively	ADV
dti-2277	12	18	,	,	PUNCT
dti-2277	12	19	both	both	PRON
dti-2277	12	20	of	of	ADP
dti-2277	12	21	which	which	PRON
dti-2277	12	22	are	be	AUX
dti-2277	12	23	immunosuppressants	immunosuppressant	NOUN
dti-2277	12	24	used	use	VERB
dti-2277	12	25	clinically	clinically	ADV
dti-2277	12	26	for	for	ADP
dti-2277	12	27	the	the	DET
dti-2277	12	28	prevention	prevention	NOUN
dti-2277	12	29	of	of	ADP
dti-2277	12	30	graft	graft	NOUN
dti-2277	12	31	rejection	rejection	NOUN
dti-2277	12	32	following	follow	VERB
dti-2277	12	33	organ	organ	NOUN
dti-2277	12	34	transplantation	transplantation	NOUN
dti-2277	12	35	(	(	PUNCT
dti-2277	12	36	handschumacher	handschumacher	ADV
dti-2277	12	37	et	et	PROPN
dti-2277	12	38	al	al	PROPN
dti-2277	12	39	.	.	PROPN
dti-2277	12	40	1984	1984	NUM
dti-2277	12	41	;	;	PUNCT
dti-2277	12	42	harding	harding	PROPN
dti-2277	12	43	et	et	PROPN
dti-2277	12	44	al	al	PROPN
dti-2277	12	45	.	.	PROPN
dti-2277	12	46	1989	1989	NUM
dti-2277	12	47	)	)	PUNCT
dti-2277	12	48	.	.	PUNCT
dti-2277	13	1	therefore	therefore	ADV
dti-2277	13	2	,	,	PUNCT
dti-2277	13	3	these	these	DET
dti-2277	13	4	ppiases	ppiase	NOUN
dti-2277	13	5	are	be	AUX
dti-2277	13	6	also	also	ADV
dti-2277	13	7	called	call	VERB
dti-2277	13	8	immunophilin	immunophilin	NOUN
dti-2277	13	9	.	.	PUNCT
dti-2277	14	1	the	the	DET
dti-2277	14	2	action	action	NOUN
dti-2277	14	3	of	of	ADP
dti-2277	14	4	ppiases	ppiase	NOUN
dti-2277	14	5	leads	lead	VERB
dti-2277	14	6	to	to	ADP
dti-2277	14	7	changes	change	NOUN
dti-2277	14	8	in	in	ADP
dti-2277	14	9	protein	protein	NOUN
dti-2277	14	10	conformation	conformation	NOUN
dti-2277	14	11	(	(	PUNCT
dti-2277	14	12	takahashi	takahashi	PROPN
dti-2277	14	13	,	,	PUNCT
dti-2277	14	14	1999	1999	NUM
dti-2277	14	15	)	)	PUNCT
dti-2277	14	16	,	,	PUNCT
dti-2277	14	17	but	but	CCONJ
dti-2277	14	18	the	the	DET
dti-2277	14	19	binding	binding	NOUN
dti-2277	14	20	of	of	ADP
dti-2277	14	21	csa	csa	PROPN
dti-2277	14	22	and	and	CCONJ
dti-2277	14	23	fk506	fk506	PROPN
dti-2277	14	24	to	to	PART
dti-2277	14	25	cyp	cyp	ADJ
dti-2277	14	26	and	and	CCONJ
dti-2277	14	27	fkbp	fkbp	ADJ
dti-2277	14	28	,	,	PUNCT
dti-2277	14	29	respectively	respectively	ADV
dti-2277	14	30	,	,	PUNCT
dti-2277	14	31	inhibits	inhibit	VERB
dti-2277	14	32	the	the	DET
dti-2277	14	33	activity	activity	NOUN
dti-2277	14	34	of	of	ADP
dti-2277	14	35	these	these	DET
dti-2277	14	36	enzymes	enzyme	NOUN
dti-2277	14	37	(	(	PUNCT
dti-2277	14	38	fischer	fischer	PROPN
dti-2277	14	39	et	et	PROPN
dti-2277	14	40	al	al	PROPN
dti-2277	14	41	.	.	PROPN
dti-2277	14	42	1989	1989	NUM
dti-2277	14	43	;	;	PUNCT
dti-2277	14	44	rosen	rosen	PROPN
dti-2277	14	45	et	et	PROPN
dti-2277	14	46	al	al	PROPN
dti-2277	14	47	.	.	PROPN
dti-2277	14	48	1990	1990	NUM
dti-2277	14	49	;	;	PUNCT
dti-2277	14	50	takahashi	takahashi	PROPN
dti-2277	14	51	et	et	PROPN
dti-2277	14	52	al	al	PROPN
dti-2277	14	53	.	.	PROPN
dti-2277	14	54	1989	1989	NUM
dti-2277	14	55	)	)	PUNCT
dti-2277	14	56	.	.	PUNCT
dti-2277	15	1	however	however	ADV
dti-2277	15	2	,	,	PUNCT
dti-2277	15	3	the	the	DET
dti-2277	15	4	inhibition	inhibition	NOUN
dti-2277	15	5	of	of	ADP
dti-2277	15	6	ppiase	ppiase	NOUN
dti-2277	15	7	activity	activity	NOUN
dti-2277	15	8	by	by	ADP
dti-2277	15	9	csa	csa	PROPN
dti-2277	15	10	and	and	CCONJ
dti-2277	15	11	fk506	fk506	PROPN
dti-2277	15	12	is	be	AUX
dti-2277	15	13	an	an	DET
dti-2277	15	14	insuffi	insuffi	ADJ
dti-2277	15	15	cient	cient	NOUN
dti-2277	15	16	requirement	requirement	NOUN
dti-2277	15	17	for	for	ADP
dti-2277	15	18	their	their	PRON
dti-2277	15	19	immunosuppressive	immunosuppressive	ADJ
dti-2277	15	20	function	function	NOUN
dti-2277	15	21	(	(	PUNCT
dti-2277	15	22	bierer	bierer	NOUN
dti-2277	15	23	et	et	PROPN
dti-2277	15	24	al	al	PROPN
dti-2277	15	25	.	.	PROPN
dti-2277	15	26	1990	1990	NUM
dti-2277	15	27	;	;	PUNCT
dti-2277	15	28	schreiber	schreiber	PROPN
dti-2277	15	29	,	,	PUNCT
dti-2277	15	30	1991	1991	NUM
dti-2277	15	31	)	)	PUNCT
dti-2277	15	32	.	.	PUNCT
dti-2277	16	1	the	the	DET
dti-2277	16	2	csa	csa	PROPN
dti-2277	16	3	/	/	SYM
dti-2277	16	4	cyp	cyp	ADJ
dti-2277	16	5	or	or	CCONJ
dti-2277	16	6	fk506	fk506	NOUN
dti-2277	16	7	/	/	SYM
dti-2277	16	8	fkbp	fkbp	PROPN
dti-2277	16	9	complex	complex	NOUN
dti-2277	16	10	,	,	PUNCT
dti-2277	16	11	subsequently	subsequently	ADV
dti-2277	16	12	interacts	interact	VERB
dti-2277	16	13	with	with	ADP
dti-2277	16	14	and	and	CCONJ
dti-2277	16	15	inhibits	inhibit	VERB
dti-2277	16	16	calcineurin	calcineurin	NOUN
dti-2277	16	17	(	(	PUNCT
dti-2277	16	18	cn	cn	PROPN
dti-2277	16	19	)	)	PUNCT
dti-2277	16	20	,	,	PUNCT
dti-2277	16	21	a	a	DET
dti-2277	16	22	phosphatase	phosphatase	NOUN
dti-2277	16	23	involved	involve	VERB
dti-2277	16	24	in	in	ADP
dti-2277	16	25	the	the	DET
dti-2277	16	26	activation	activation	NOUN
dti-2277	16	27	of	of	ADP
dti-2277	16	28	the	the	DET
dti-2277	16	29	transcription	transcription	NOUN
dti-2277	16	30	factor	factor	NOUN
dti-2277	16	31	nf	nf	NOUN
dti-2277	16	32	-	-	PUNCT
dti-2277	16	33	at	at	NOUN
dti-2277	16	34	.	.	PUNCT
dti-2277	17	1	proper	proper	ADJ
dti-2277	17	2	nf	nf	VERB
dti-2277	17	3	-	-	PUNCT
dti-2277	17	4	at	at	NOUN
dti-2277	17	5	function	function	NOUN
dti-2277	17	6	is	be	AUX
dti-2277	17	7	essential	essential	ADJ
dti-2277	17	8	for	for	ADP
dti-2277	17	9	the	the	DET
dti-2277	17	10	generation	generation	NOUN
dti-2277	17	11	of	of	ADP
dti-2277	17	12	a	a	DET
dti-2277	17	13	productive	productive	ADJ
dti-2277	17	14	t	t	NOUN
dti-2277	17	15	cell	cell	NOUN
dti-2277	17	16	response	response	NOUN
dti-2277	17	17	(	(	PUNCT
dti-2277	17	18	clipstone	clipstone	NOUN
dti-2277	17	19	and	and	CCONJ
dti-2277	17	20	crabtree	crabtree	PROPN
dti-2277	17	21	,	,	PUNCT
dti-2277	17	22	1992	1992	NUM
dti-2277	17	23	;	;	PUNCT
dti-2277	17	24	fruman	fruman	NOUN
dti-2277	17	25	et	et	PROPN
dti-2277	17	26	al	al	PROPN
dti-2277	17	27	.	.	PROPN
dti-2277	17	28	1992	1992	NUM
dti-2277	17	29	;	;	PUNCT
dti-2277	17	30	liu	liu	PROPN
dti-2277	17	31	et	et	PROPN
dti-2277	17	32	al	al	PROPN
dti-2277	17	33	.	.	PROPN
dti-2277	17	34	1991	1991	NUM
dti-2277	17	35	)	)	PUNCT
dti-2277	17	36	.	.	PUNCT
dti-2277	18	1	in	in	ADP
dti-2277	18	2	the	the	DET
dti-2277	18	3	absence	absence	NOUN
dti-2277	18	4	of	of	ADP
dti-2277	18	5	immunosuppressants	immunosuppressant	NOUN
dti-2277	18	6	,	,	PUNCT
dti-2277	18	7	cn	cn	PROPN
dti-2277	18	8	dephosphorylates	dephosphorylates	PROPN
dti-2277	18	9	cytoplasmic	cytoplasmic	ADJ
dti-2277	18	10	nf	nf	NOUN
dti-2277	18	11	-	-	PUNCT
dti-2277	18	12	at	at	NOUN
dti-2277	18	13	,	,	PUNCT
dti-2277	18	14	leading	lead	VERB
dti-2277	18	15	to	to	ADP
dti-2277	18	16	nf	nf	VERB
dti-2277	18	17	-	-	PUNCT
dti-2277	18	18	at	at	NOUN
dti-2277	18	19	nuclear	nuclear	ADJ
dti-2277	18	20	translocation	translocation	NOUN
dti-2277	18	21	and	and	CCONJ
dti-2277	18	22	transactivation	transactivation	NOUN
dti-2277	18	23	of	of	ADP
dti-2277	18	24	downstream	downstream	ADJ
dti-2277	18	25	genes	gene	NOUN
dti-2277	18	26	participating	participate	VERB
dti-2277	18	27	in	in	ADP
dti-2277	18	28	the	the	DET
dti-2277	18	29	immune	immune	ADJ
dti-2277	18	30	response	response	NOUN
dti-2277	18	31	(	(	PUNCT
dti-2277	18	32	liu	liu	PROPN
dti-2277	18	33	et	et	PROPN
dti-2277	18	34	al	al	PROPN
dti-2277	18	35	.	.	PROPN
dti-2277	18	36	1992	1992	NUM
dti-2277	18	37	;	;	PUNCT
dti-2277	18	38	mccaffrey	mccaffrey	PROPN
dti-2277	18	39	et	et	PROPN
dti-2277	18	40	al	al	PROPN
dti-2277	18	41	.	.	PROPN
dti-2277	18	42	1993	1993	NUM
dti-2277	18	43	)	)	PUNCT
dti-2277	18	44	.	.	PUNCT
dti-2277	19	1	csa	csa	PROPN
dti-2277	19	2	and	and	CCONJ
dti-2277	19	3	fk506	fk506	PROPN
dti-2277	19	4	prevent	prevent	VERB
dti-2277	19	5	the	the	DET
dti-2277	19	6	dephosphorylation	dephosphorylation	NOUN
dti-2277	19	7	and	and	CCONJ
dti-2277	19	8	subsequent	subsequent	ADJ
dti-2277	19	9	nuclear	nuclear	ADJ
dti-2277	19	10	translocation	translocation	NOUN
dti-2277	19	11	of	of	ADP
dti-2277	19	12	nf	nf	NOUN
dti-2277	19	13	-	-	PUNCT
dti-2277	19	14	at	at	NOUN
dti-2277	19	15	leading	lead	VERB
dti-2277	19	16	to	to	ADP
dti-2277	19	17	immunosuppression	immunosuppression	NOUN
dti-2277	19	18	.	.	PUNCT
dti-2277	20	1	role	role	NOUN
dti-2277	20	2	of	of	ADP
dti-2277	20	3	cyp	cyp	ADJ
dti-2277	20	4	family	family	NOUN
dti-2277	20	5	members	member	NOUN
dti-2277	20	6	in	in	ADP
dti-2277	20	7	cellular	cellular	ADJ
dti-2277	20	8	events	event	NOUN
dti-2277	20	9	more	more	ADJ
dti-2277	20	10	than	than	ADP
dti-2277	20	11	10	10	NUM
dti-2277	20	12	cyp	cyp	ADJ
dti-2277	20	13	subtypes	subtype	NOUN
dti-2277	20	14	are	be	AUX
dti-2277	20	15	found	find	VERB
dti-2277	20	16	in	in	ADP
dti-2277	20	17	mammals	mammal	NOUN
dti-2277	20	18	(	(	PUNCT
dti-2277	20	19	table	table	NOUN
dti-2277	20	20	1	1	NUM
dti-2277	20	21	)	)	PUNCT
dti-2277	20	22	.	.	PUNCT
dti-2277	21	1	the	the	DET
dti-2277	21	2	subcellular	subcellular	ADJ
dti-2277	21	3	localization	localization	NOUN
dti-2277	21	4	of	of	ADP
dti-2277	21	5	cyps	cyps	PROPN
dti-2277	21	6	varies	vary	VERB
dti-2277	21	7	.	.	PUNCT
dti-2277	22	1	cypa	cypa	PROPN
dti-2277	22	2	is	be	AUX
dti-2277	22	3	primarily	primarily	ADV
dti-2277	22	4	found	find	VERB
dti-2277	22	5	in	in	ADP
dti-2277	22	6	the	the	DET
dti-2277	22	7	cytoplasm	cytoplasm	NOUN
dti-2277	22	8	,	,	PUNCT
dti-2277	22	9	while	while	SCONJ
dti-2277	22	10	cypb	cypb	PROPN
dti-2277	22	11	,	,	PUNCT
dti-2277	22	12	cypd	cypd	PROPN
dti-2277	22	13	,	,	PUNCT
dti-2277	22	14	cype	cype	NOUN
dti-2277	22	15	,	,	PUNCT
dti-2277	22	16	and	and	CCONJ
dti-2277	22	17	ranbp2	ranbp2	NOUN
dti-2277	22	18	are	be	AUX
dti-2277	22	19	distributed	distribute	VERB
dti-2277	22	20	in	in	ADP
dti-2277	22	21	the	the	DET
dti-2277	22	22	endoplasmic	endoplasmic	ADJ
dti-2277	22	23	reticulum	reticulum	NOUN
dti-2277	22	24	(	(	PUNCT
dti-2277	22	25	er	er	INTJ
dti-2277	22	26	)	)	PUNCT
dti-2277	22	27	,	,	PUNCT
dti-2277	22	28	mitochondria	mitochondria	PROPN
dti-2277	22	29	,	,	PUNCT
dti-2277	22	30	nucleus	nucleus	NOUN
dti-2277	22	31	,	,	PUNCT
dti-2277	22	32	and	and	CCONJ
dti-2277	22	33	nuclear	nuclear	ADJ
dti-2277	22	34	pore	pore	NOUN
dti-2277	22	35	,	,	PUNCT
dti-2277	22	36	respectively	respectively	ADV
dti-2277	22	37	.	.	PUNCT
dti-2277	23	1	members	member	NOUN
dti-2277	23	2	of	of	ADP
dti-2277	23	3	the	the	DET
dti-2277	23	4	cyp	cyp	ADJ
dti-2277	23	5	family	family	NOUN
dti-2277	23	6	play	play	VERB
dti-2277	23	7	roles	role	NOUN
dti-2277	23	8	in	in	ADP
dti-2277	23	9	a	a	DET
dti-2277	23	10	variety	variety	NOUN
dti-2277	23	11	of	of	ADP
dti-2277	23	12	cellular	cellular	ADJ
dti-2277	23	13	processes	process	NOUN
dti-2277	23	14	including	include	VERB
dti-2277	23	15	the	the	DET
dti-2277	23	16	immune	immune	ADJ
dti-2277	23	17	response	response	NOUN
dti-2277	23	18	,	,	PUNCT
dti-2277	23	19	transcription	transcription	NOUN
dti-2277	23	20	,	,	PUNCT
dti-2277	23	21	mitochondrial	mitochondrial	ADJ
dti-2277	23	22	function	function	NOUN
dti-2277	23	23	,	,	PUNCT
dti-2277	23	24	cell	cell	NOUN
dti-2277	23	25	death	death	NOUN
dti-2277	23	26	,	,	PUNCT
dti-2277	23	27	and	and	CCONJ
dti-2277	23	28	chemotaxis	chemotaxis	ADJ
dti-2277	23	29	,	,	PUNCT
dti-2277	23	30	as	as	SCONJ
dti-2277	23	31	described	describe	VERB
dti-2277	23	32	below	below	ADV
dti-2277	23	33	.	.	PUNCT
dti-2277	24	1	while	while	SCONJ
dti-2277	24	2	a	a	DET
dti-2277	24	3	number	number	NOUN
dti-2277	24	4	of	of	ADP
dti-2277	24	5	cyp	cyp	ADJ
dti-2277	24	6	family	family	NOUN
dti-2277	24	7	members	member	NOUN
dti-2277	24	8	have	have	AUX
dti-2277	24	9	been	be	AUX
dti-2277	24	10	ideitifi	ideitifi	ADJ
dti-2277	24	11	ed	ed	NOUN
dti-2277	24	12	,	,	PUNCT
dti-2277	24	13	intensive	intensive	ADJ
dti-2277	24	14	functional	functional	ADJ
dti-2277	24	15	analysis	analysis	NOUN
dti-2277	24	16	has	have	AUX
dti-2277	24	17	been	be	AUX
dti-2277	24	18	performed	perform	VERB
dti-2277	24	19	on	on	ADP
dti-2277	24	20	only	only	ADV
dti-2277	24	21	a	a	DET
dti-2277	24	22	few	few	ADJ
dti-2277	24	23	including	include	VERB
dti-2277	24	24	cypa	cypa	PROPN
dti-2277	24	25	,	,	PUNCT
dti-2277	24	26	cypb	cypb	PROPN
dti-2277	24	27	,	,	PUNCT
dti-2277	24	28	cypd	cypd	PROPN
dti-2277	24	29	,	,	PUNCT
dti-2277	24	30	and	and	CCONJ
dti-2277	24	31	cyp40	cyp40	ADJ
dti-2277	24	32	.	.	PUNCT
dti-2277	25	1	cypa	cypa	PROPN
dti-2277	25	2	is	be	AUX
dti-2277	25	3	the	the	DET
dti-2277	25	4	most	most	ADV
dti-2277	25	5	abundant	abundant	ADJ
dti-2277	25	6	cyp	cyp	ADJ
dti-2277	25	7	subtype	subtype	NOUN
dti-2277	25	8	found	find	VERB
dti-2277	25	9	in	in	ADP
dti-2277	25	10	the	the	DET
dti-2277	25	11	cells	cell	NOUN
dti-2277	25	12	(	(	PUNCT
dti-2277	25	13	waldmeier	waldmei	ADJ
dti-2277	25	14	et	et	PROPN
dti-2277	25	15	al	al	PROPN
dti-2277	25	16	.	.	PROPN
dti-2277	25	17	2003	2003	NUM
dti-2277	25	18	)	)	PUNCT
dti-2277	25	19	,	,	PUNCT
dti-2277	25	20	and	and	CCONJ
dti-2277	25	21	it	it	PRON
dti-2277	25	22	is	be	AUX
dti-2277	25	23	the	the	DET
dti-2277	25	24	primary	primary	ADJ
dti-2277	25	25	factor	factor	NOUN
dti-2277	25	26	mediating	mediate	VERB
dti-2277	25	27	the	the	DET
dti-2277	25	28	immunosuppressive	immunosuppressive	ADJ
dti-2277	25	29	effects	effect	NOUN
dti-2277	25	30	of	of	ADP
dti-2277	25	31	csa	csa	PROPN
dti-2277	25	32	(	(	PUNCT
dti-2277	25	33	colgan	colgan	PROPN
dti-2277	25	34	et	et	PROPN
dti-2277	25	35	al	al	PROPN
dti-2277	25	36	.	.	PROPN
dti-2277	25	37	2005	2005	NUM
dti-2277	25	38	)	)	PUNCT
dti-2277	25	39	.	.	PUNCT
dti-2277	26	1	however	however	ADV
dti-2277	26	2	,	,	PUNCT
dti-2277	26	3	even	even	ADV
dti-2277	26	4	in	in	ADP
dti-2277	26	5	the	the	DET
dti-2277	26	6	absence	absence	NOUN
dti-2277	26	7	of	of	ADP
dti-2277	26	8	csa	csa	PROPN
dti-2277	26	9	,	,	PUNCT
dti-2277	26	10	cypa	cypa	PROPN
dti-2277	26	11	plays	play	VERB
dti-2277	26	12	an	an	DET
dti-2277	26	13	important	important	ADJ
dti-2277	26	14	role	role	NOUN
dti-2277	26	15	in	in	ADP
dti-2277	26	16	regulating	regulate	VERB
dti-2277	26	17	the	the	DET
dti-2277	26	18	immune	immune	ADJ
dti-2277	26	19	responses	response	NOUN
dti-2277	26	20	as	as	SCONJ
dti-2277	26	21	seen	see	VERB
dti-2277	26	22	in	in	ADP
dti-2277	26	23	drug	drug	NOUN
dti-2277	26	24	target	target	NOUN
dti-2277	26	25	insights	insight	NOUN
dti-2277	26	26	2007	2007	NUM
dti-2277	26	27	:	:	PUNCT
dti-2277	26	28	2	2	NUM
dti-2277	26	29	9–18	9–18	NUM
dti-2277	26	30	10	10	NUM
dti-2277	26	31	watashi	watashi	NOUN
dti-2277	26	32	and	and	CCONJ
dti-2277	26	33	shimotohno	shimotohno	NOUN
dti-2277	26	34	cypa	cypa	PROPN
dti-2277	26	35	-	-	PUNCT
dti-2277	26	36	defi	defi	PROPN
dti-2277	26	37	cient	cient	NOUN
dti-2277	26	38	mice	mouse	NOUN
dti-2277	26	39	.	.	PUNCT
dti-2277	27	1	cypa	cypa	ADJ
dti-2277	27	2	-	-	PUNCT
dti-2277	27	3	knockout	knockout	NOUN
dti-2277	27	4	mice	mouse	NOUN
dti-2277	27	5	have	have	VERB
dti-2277	27	6	an	an	DET
dti-2277	27	7	“	"	PUNCT
dti-2277	27	8	allergic	allergic	ADJ
dti-2277	27	9	”	"	PUNCT
dti-2277	27	10	phenotype	phenotype	NOUN
dti-2277	27	11	with	with	ADP
dti-2277	27	12	increased	increase	VERB
dti-2277	27	13	serum	serum	NOUN
dti-2277	27	14	igg1	igg1	NOUN
dti-2277	27	15	and	and	CCONJ
dti-2277	27	16	ige	ige	PROPN
dti-2277	27	17	levels	level	NOUN
dti-2277	27	18	and	and	CCONJ
dti-2277	27	19	tissue	tissue	NOUN
dti-2277	27	20	infi	infi	NOUN
dti-2277	27	21	ltration	ltration	NOUN
dti-2277	27	22	by	by	ADP
dti-2277	27	23	mononuclear	mononuclear	ADJ
dti-2277	27	24	cells	cell	NOUN
dti-2277	27	25	,	,	PUNCT
dti-2277	27	26	eosinophils	eosinophil	NOUN
dti-2277	27	27	,	,	PUNCT
dti-2277	27	28	and	and	CCONJ
dti-2277	27	29	mast	mast	NOUN
dti-2277	27	30	cells	cell	NOUN
dti-2277	27	31	(	(	PUNCT
dti-2277	27	32	colgan	colgan	PROPN
dti-2277	27	33	et	et	PROPN
dti-2277	27	34	al	al	PROPN
dti-2277	27	35	.	.	PROPN
dti-2277	27	36	2004	2004	NUM
dti-2277	27	37	)	)	PUNCT
dti-2277	27	38	,	,	PUNCT
dti-2277	27	39	related	relate	VERB
dti-2277	27	40	to	to	ADP
dti-2277	27	41	increased	increase	VERB
dti-2277	27	42	and	and	CCONJ
dti-2277	27	43	dysregulated	dysregulated	ADJ
dti-2277	27	44	activity	activity	NOUN
dti-2277	27	45	of	of	ADP
dti-2277	27	46	th2	th2	PROPN
dti-2277	27	47	cd4	cd4	PROPN
dti-2277	27	48	+	+	PROPN
dti-2277	27	49	t	t	NOUN
dti-2277	27	50	cells	cell	NOUN
dti-2277	27	51	.	.	PUNCT
dti-2277	28	1	in	in	ADP
dti-2277	28	2	cypa	cypa	PROPN
dti-2277	28	3	-	-	PUNCT
dti-2277	28	4	knockout	knockout	NOUN
dti-2277	28	5	cells	cell	NOUN
dti-2277	28	6	,	,	PUNCT
dti-2277	28	7	interleukin-2	interleukin-2	NUM
dti-2277	28	8	tyrosine	tyrosine	NOUN
dti-2277	28	9	kinase	kinase	NOUN
dti-2277	28	10	(	(	PUNCT
dti-2277	28	11	itk	itk	PROPN
dti-2277	28	12	)	)	PUNCT
dti-2277	28	13	,	,	PUNCT
dti-2277	28	14	a	a	DET
dti-2277	28	15	signaling	signal	VERB
dti-2277	28	16	molecule	molecule	NOUN
dti-2277	28	17	crucial	crucial	ADJ
dti-2277	28	18	for	for	ADP
dti-2277	28	19	the	the	DET
dti-2277	28	20	development	development	NOUN
dti-2277	28	21	of	of	ADP
dti-2277	28	22	a	a	DET
dti-2277	28	23	th2	th2	PROPN
dti-2277	28	24	response	response	NOUN
dti-2277	28	25	,	,	PUNCT
dti-2277	28	26	is	be	AUX
dti-2277	28	27	constitutively	constitutively	ADV
dti-2277	28	28	activated	activate	VERB
dti-2277	28	29	.	.	PUNCT
dti-2277	29	1	itk	itk	PROPN
dti-2277	29	2	is	be	AUX
dti-2277	29	3	a	a	DET
dti-2277	29	4	member	member	NOUN
dti-2277	29	5	of	of	ADP
dti-2277	29	6	the	the	DET
dti-2277	29	7	tec	tec	ADJ
dti-2277	29	8	family	family	NOUN
dti-2277	29	9	of	of	ADP
dti-2277	29	10	sh2	sh2	PROPN
dti-2277	29	11	/	/	SYM
dti-2277	29	12	sh3	sh3	NOUN
dti-2277	29	13	-	-	PUNCT
dti-2277	29	14	containing	contain	VERB
dti-2277	29	15	tyrosine	tyrosine	NOUN
dti-2277	29	16	kinases	kinase	NOUN
dti-2277	29	17	,	,	PUNCT
dti-2277	29	18	and	and	CCONJ
dti-2277	29	19	it	it	PRON
dti-2277	29	20	participates	participate	VERB
dti-2277	29	21	in	in	ADP
dti-2277	29	22	the	the	DET
dti-2277	29	23	signal	signal	ADJ
dti-2277	29	24	transduction	transduction	NOUN
dti-2277	29	25	cascade	cascade	NOUN
dti-2277	29	26	leading	lead	VERB
dti-2277	29	27	to	to	ADP
dti-2277	29	28	t	t	NOUN
dti-2277	29	29	cell	cell	NOUN
dti-2277	29	30	activation	activation	NOUN
dti-2277	29	31	.	.	PUNCT
dti-2277	30	1	cypa	cypa	PROPN
dti-2277	30	2	can	can	AUX
dti-2277	30	3	bind	bind	VERB
dti-2277	30	4	itk	itk	PROPN
dti-2277	30	5	,	,	PUNCT
dti-2277	30	6	and	and	CCONJ
dti-2277	30	7	this	this	PRON
dti-2277	30	8	negatively	negatively	ADV
dti-2277	30	9	regulates	regulate	VERB
dti-2277	30	10	itk	itk	PROPN
dti-2277	30	11	activity	activity	NOUN
dti-2277	30	12	(	(	PUNCT
dti-2277	30	13	brazin	brazin	PROPN
dti-2277	30	14	et	et	PROPN
dti-2277	30	15	al	al	PROPN
dti-2277	30	16	.	.	PROPN
dti-2277	30	17	2002	2002	NUM
dti-2277	30	18	)	)	PUNCT
dti-2277	30	19	.	.	PUNCT
dti-2277	31	1	thus	thus	ADV
dti-2277	31	2	,	,	PUNCT
dti-2277	31	3	cypa	cypa	PROPN
dti-2277	31	4	plays	play	VERB
dti-2277	31	5	a	a	DET
dti-2277	31	6	suppressive	suppressive	ADJ
dti-2277	31	7	role	role	NOUN
dti-2277	31	8	in	in	ADP
dti-2277	31	9	the	the	DET
dti-2277	31	10	development	development	NOUN
dti-2277	31	11	of	of	ADP
dti-2277	31	12	cd4	cd4	PROPN
dti-2277	31	13	+	+	PROPN
dti-2277	31	14	t	t	NOUN
dti-2277	31	15	cell	cell	NOUN
dti-2277	31	16	responses	response	NOUN
dti-2277	31	17	through	through	ADP
dti-2277	31	18	its	its	PRON
dti-2277	31	19	interaction	interaction	NOUN
dti-2277	31	20	with	with	ADP
dti-2277	31	21	itk	itk	PROPN
dti-2277	31	22	.	.	PUNCT
dti-2277	32	1	other	other	PROPN
dti-2277	32	2	s	s	PART
dti-2277	32	3	tudies	tudie	NOUN
dti-2277	32	4	have	have	VERB
dti-2277	32	5	repor	repor	PROPN
dti-2277	32	6	ted	ted	PROPN
dti-2277	32	7	severa	severa	PROPN
dti-2277	32	8	l	l	PROPN
dti-2277	32	9	non	non	ADJ
dti-2277	32	10	-	-	ADJ
dti-2277	32	11	immune	immune	ADJ
dti-2277	32	12	system	system	NOUN
dti-2277	32	13	roles	role	NOUN
dti-2277	32	14	for	for	ADP
dti-2277	32	15	cypa	cypa	NOUN
dti-2277	32	16	.	.	PUNCT
dti-2277	33	1	cypa	cypa	PROPN
dti-2277	33	2	interacts	interact	VERB
dti-2277	33	3	with	with	ADP
dti-2277	33	4	apoptosis	apoptosis	NOUN
dti-2277	33	5	-	-	PUNCT
dti-2277	33	6	inducing	induce	VERB
dti-2277	33	7	factor	factor	NOUN
dti-2277	33	8	(	(	PUNCT
dti-2277	33	9	aif	aif	PROPN
dti-2277	33	10	)	)	PUNCT
dti-2277	33	11	and	and	CCONJ
dti-2277	33	12	promotes	promote	VERB
dti-2277	33	13	aif	aif	PROPN
dti-2277	33	14	-	-	PUNCT
dti-2277	33	15	mediated	mediate	VERB
dti-2277	33	16	chromatinolysis	chromatinolysis	NOUN
dti-2277	33	17	during	during	ADP
dti-2277	33	18	apoptosis	apoptosis	NOUN
dti-2277	33	19	(	(	PUNCT
dti-2277	33	20	cande	cande	PROPN
dti-2277	33	21	et	et	PROPN
dti-2277	33	22	al	al	PROPN
dti-2277	33	23	.	.	PROPN
dti-2277	33	24	2004	2004	NUM
dti-2277	33	25	)	)	PUNCT
dti-2277	33	26	.	.	PUNCT
dti-2277	34	1	additionally	additionally	ADV
dti-2277	34	2	,	,	PUNCT
dti-2277	34	3	cypa	cypa	PROPN
dti-2277	34	4	interacts	interact	VERB
dti-2277	34	5	with	with	ADP
dti-2277	34	6	membrane	membrane	NOUN
dti-2277	34	7	-	-	PUNCT
dti-2277	34	8	bound	bind	VERB
dti-2277	34	9	guanylate	guanylate	NOUN
dti-2277	34	10	cyclase	cyclase	NOUN
dti-2277	34	11	-	-	PUNCT
dti-2277	34	12	a	a	DET
dti-2277	34	13	(	(	PUNCT
dti-2277	34	14	gc	gc	PROPN
dti-2277	34	15	-	-	PUNCT
dti-2277	34	16	a	a	NOUN
dti-2277	34	17	)	)	PUNCT
dti-2277	34	18	,	,	PUNCT
dti-2277	34	19	a	a	DET
dti-2277	34	20	receptor	receptor	NOUN
dti-2277	34	21	for	for	ADP
dti-2277	34	22	atrial	atrial	ADJ
dti-2277	34	23	natriuretic	natriuretic	ADJ
dti-2277	34	24	factor	factor	NOUN
dti-2277	34	25	(	(	PUNCT
dti-2277	34	26	anf	anf	PROPN
dti-2277	34	27	)	)	PUNCT
dti-2277	34	28	(	(	PUNCT
dti-2277	34	29	chen	chen	PROPN
dti-2277	34	30	et	et	PROPN
dti-2277	34	31	al	al	PROPN
dti-2277	34	32	.	.	PROPN
dti-2277	34	33	2004	2004	NUM
dti-2277	34	34	)	)	PUNCT
dti-2277	34	35	.	.	PUNCT
dti-2277	35	1	gc	gc	PROPN
dti-2277	35	2	-	-	PUNCT
dti-2277	35	3	a	a	NOUN
dti-2277	35	4	and	and	CCONJ
dti-2277	35	5	anf	anf	NOUN
dti-2277	35	6	are	be	AUX
dti-2277	35	7	involved	involve	VERB
dti-2277	35	8	in	in	ADP
dti-2277	35	9	cardiovascular	cardiovascular	ADJ
dti-2277	35	10	homeostasis	homeostasis	NOUN
dti-2277	35	11	,	,	PUNCT
dti-2277	35	12	and	and	CCONJ
dti-2277	35	13	cypa	cypa	PROPN
dti-2277	35	14	appears	appear	VERB
dti-2277	35	15	to	to	PART
dti-2277	35	16	function	function	VERB
dti-2277	35	17	as	as	ADP
dti-2277	35	18	an	an	DET
dti-2277	35	19	endogenous	endogenous	ADJ
dti-2277	35	20	inhibitor	inhibitor	NOUN
dti-2277	35	21	of	of	ADP
dti-2277	35	22	gc	gc	PROPN
dti-2277	35	23	-	-	PUNCT
dti-2277	35	24	a	a	DET
dti-2277	35	25	activation	activation	NOUN
dti-2277	35	26	by	by	ADP
dti-2277	35	27	competing	compete	VERB
dti-2277	35	28	for	for	ADP
dti-2277	35	29	anf	anf	NOUN
dti-2277	35	30	binding	binding	NOUN
dti-2277	35	31	.	.	PUNCT
dti-2277	36	1	further	further	ADJ
dti-2277	36	2	interactions	interaction	NOUN
dti-2277	36	3	of	of	ADP
dti-2277	36	4	cypa	cypa	PROPN
dti-2277	36	5	with	with	ADP
dti-2277	36	6	prolactin	prolactin	ADJ
dti-2277	36	7	receptor	receptor	NOUN
dti-2277	36	8	(	(	PUNCT
dti-2277	36	9	syed	syed	PROPN
dti-2277	36	10	et	et	PROPN
dti-2277	36	11	al	al	PROPN
dti-2277	36	12	.	.	PROPN
dti-2277	36	13	2003	2003	NUM
dti-2277	36	14	)	)	PUNCT
dti-2277	36	15	and	and	CCONJ
dti-2277	36	16	transcription	transcription	NOUN
dti-2277	36	17	factor	factor	NOUN
dti-2277	36	18	yy1	yy1	PROPN
dti-2277	36	19	(	(	PUNCT
dti-2277	36	20	yang	yang	PROPN
dti-2277	36	21	et	et	PROPN
dti-2277	36	22	al	al	PROPN
dti-2277	36	23	.	.	PROPN
dti-2277	36	24	1995	1995	NUM
dti-2277	36	25	)	)	PUNCT
dti-2277	36	26	have	have	AUX
dti-2277	36	27	been	be	AUX
dti-2277	36	28	observed	observe	VERB
dti-2277	36	29	,	,	PUNCT
dti-2277	36	30	but	but	CCONJ
dti-2277	36	31	the	the	DET
dti-2277	36	32	exact	exact	ADJ
dti-2277	36	33	role	role	NOUN
dti-2277	36	34	of	of	ADP
dti-2277	36	35	cypa	cypa	PROPN
dti-2277	36	36	in	in	ADP
dti-2277	36	37	these	these	DET
dti-2277	36	38	processes	process	NOUN
dti-2277	36	39	remains	remain	VERB
dti-2277	36	40	unclear	unclear	ADJ
dti-2277	36	41	.	.	PUNCT
dti-2277	37	1	cypa	cypa	PROPN
dti-2277	37	2	was	be	AUX
dti-2277	37	3	also	also	ADV
dti-2277	37	4	observed	observe	VERB
dti-2277	37	5	to	to	PART
dti-2277	37	6	bind	bind	VERB
dti-2277	37	7	dna	dna	NOUN
dti-2277	37	8	in	in	ADP
dti-2277	37	9	a	a	DET
dti-2277	37	10	zinc	zinc	NOUN
dti-2277	37	11	-	-	PUNCT
dti-2277	37	12	dependent	dependent	ADJ
dti-2277	37	13	manner	manner	NOUN
dti-2277	37	14	in	in	ADP
dti-2277	37	15	a	a	DET
dti-2277	37	16	mouse	mouse	NOUN
dti-2277	37	17	macrophage	macrophage	ADJ
dti-2277	37	18	cell	cell	NOUN
dti-2277	37	19	line	line	NOUN
dti-2277	37	20	(	(	PUNCT
dti-2277	37	21	krummrei	krummrei	NOUN
dti-2277	37	22	et	et	PROPN
dti-2277	37	23	al	al	PROPN
dti-2277	37	24	.	.	PROPN
dti-2277	37	25	1995	1995	NUM
dti-2277	37	26	)	)	PUNCT
dti-2277	37	27	.	.	PUNCT
dti-2277	38	1	however	however	ADV
dti-2277	38	2	,	,	PUNCT
dti-2277	38	3	the	the	DET
dti-2277	38	4	best	well	ADV
dti-2277	38	5	-	-	PUNCT
dti-2277	38	6	characterized	characterize	VERB
dti-2277	38	7	role	role	NOUN
dti-2277	38	8	identified	identify	VERB
dti-2277	38	9	for	for	ADP
dti-2277	38	10	cypa	cypa	PROPN
dti-2277	38	11	is	be	AUX
dti-2277	38	12	not	not	PART
dti-2277	38	13	in	in	ADP
dti-2277	38	14	normal	normal	ADJ
dti-2277	38	15	cellular	cellular	ADJ
dti-2277	38	16	physiology	physiology	NOUN
dti-2277	38	17	,	,	PUNCT
dti-2277	38	18	but	but	CCONJ
dti-2277	38	19	rather	rather	ADV
dti-2277	38	20	as	as	ADP
dti-2277	38	21	co	co	NOUN
dti-2277	38	22	-	-	NOUN
dti-2277	38	23	factor	factor	NOUN
dti-2277	38	24	during	during	ADP
dti-2277	38	25	the	the	DET
dti-2277	38	26	human	human	ADJ
dti-2277	38	27	immunodefi	immunodefi	NOUN
dti-2277	38	28	ciency	ciency	NOUN
dti-2277	38	29	virus-1	virus-1	CCONJ
dti-2277	38	30	(	(	PUNCT
dti-2277	38	31	hiv-1	hiv-1	X
dti-2277	38	32	)	)	PUNCT
dti-2277	38	33	viral	viral	ADJ
dti-2277	38	34	life	life	NOUN
dti-2277	38	35	cycle	cycle	NOUN
dti-2277	38	36	(	(	PUNCT
dti-2277	38	37	see	see	VERB
dti-2277	38	38	below	below	ADV
dti-2277	38	39	)	)	PUNCT
dti-2277	38	40	.	.	PUNCT
dti-2277	39	1	cypb	cypb	PROPN
dti-2277	39	2	was	be	AUX
dti-2277	39	3	originally	originally	ADV
dti-2277	39	4	identifi	identifi	NOUN
dti-2277	39	5	ed	ed	NOUN
dti-2277	39	6	as	as	ADP
dti-2277	39	7	a	a	DET
dti-2277	39	8	cyp	cyp	ADJ
dti-2277	39	9	family	family	NOUN
dti-2277	39	10	member	member	NOUN
dti-2277	39	11	bearing	bear	VERB
dti-2277	39	12	a	a	DET
dti-2277	39	13	signal	signal	ADJ
dti-2277	39	14	sequence	sequence	NOUN
dti-2277	39	15	leading	lead	VERB
dti-2277	39	16	to	to	ADP
dti-2277	39	17	the	the	DET
dti-2277	39	18	er	er	INTJ
dti-2277	39	19	lumen	luman	NOUN
dti-2277	39	20	or	or	CCONJ
dti-2277	39	21	the	the	DET
dti-2277	39	22	secretory	secretory	ADJ
dti-2277	39	23	pathway	pathway	NOUN
dti-2277	39	24	(	(	PUNCT
dti-2277	39	25	price	price	NOUN
dti-2277	39	26	et	et	PROPN
dti-2277	39	27	al	al	PROPN
dti-2277	39	28	.	.	PROPN
dti-2277	39	29	1991	1991	NUM
dti-2277	39	30	)	)	PUNCT
dti-2277	39	31	,	,	PUNCT
dti-2277	39	32	but	but	CCONJ
dti-2277	39	33	the	the	DET
dti-2277	39	34	specifi	specifi	PROPN
dti-2277	39	35	c	c	PROPN
dti-2277	39	36	function	function	NOUN
dti-2277	39	37	of	of	ADP
dti-2277	39	38	cypb	cypb	PROPN
dti-2277	39	39	is	be	AUX
dti-2277	39	40	poorly	poorly	ADV
dti-2277	39	41	understood	understand	VERB
dti-2277	39	42	.	.	PUNCT
dti-2277	40	1	a	a	DET
dti-2277	40	2	yeast	yeast	NOUN
dti-2277	40	3	two	two	NUM
dti-2277	40	4	-	-	PUNCT
dti-2277	40	5	hybrid	hybrid	ADJ
dti-2277	40	6	screening	screening	NOUN
dti-2277	40	7	using	use	VERB
dti-2277	40	8	cypb	cypb	PROPN
dti-2277	40	9	as	as	SCONJ
dti-2277	40	10	a	a	DET
dti-2277	40	11	bait	bait	NOUN
dti-2277	40	12	identified	identify	VERB
dti-2277	40	13	an	an	DET
dti-2277	40	14	interaction	interaction	NOUN
dti-2277	40	15	with	with	ADP
dti-2277	40	16	calcium	calcium	NOUN
dti-2277	40	17	-	-	PUNCT
dti-2277	40	18	signal	signal	NOUN
dti-2277	40	19	modulating	modulate	VERB
dti-2277	40	20	cyclophilin	cyclophilin	PROPN
dti-2277	40	21	ligand	ligand	NOUN
dti-2277	40	22	(	(	PUNCT
dti-2277	40	23	caml	caml	PROPN
dti-2277	40	24	)	)	PUNCT
dti-2277	40	25	(	(	PUNCT
dti-2277	40	26	bram	bram	PROPN
dti-2277	40	27	and	and	CCONJ
dti-2277	40	28	crabtree	crabtree	PROPN
dti-2277	40	29	,	,	PUNCT
dti-2277	40	30	1994	1994	NUM
dti-2277	40	31	)	)	PUNCT
dti-2277	40	32	.	.	PUNCT
dti-2277	41	1	caml	caml	PROPN
dti-2277	41	2	is	be	AUX
dti-2277	41	3	located	locate	VERB
dti-2277	41	4	on	on	ADP
dti-2277	41	5	the	the	DET
dti-2277	41	6	cytoplasmic	cytoplasmic	ADJ
dti-2277	41	7	face	face	NOUN
dti-2277	41	8	of	of	ADP
dti-2277	41	9	the	the	DET
dti-2277	41	10	er	er	INTJ
dti-2277	41	11	membrane	membrane	NOUN
dti-2277	41	12	(	(	PUNCT
dti-2277	41	13	holloway	holloway	PROPN
dti-2277	41	14	and	and	CCONJ
dti-2277	41	15	bram	bram	PROPN
dti-2277	41	16	,	,	PUNCT
dti-2277	41	17	1998	1998	NUM
dti-2277	41	18	)	)	PUNCT
dti-2277	41	19	.	.	PUNCT
dti-2277	42	1	caml	caml	PROPN
dti-2277	42	2	participates	participate	VERB
dti-2277	42	3	in	in	ADP
dti-2277	42	4	calcium	calcium	NOUN
dti-2277	42	5	signal	signal	NOUN
dti-2277	42	6	transduction	transduction	NOUN
dti-2277	42	7	pathway	pathway	NOUN
dti-2277	42	8	and	and	CCONJ
dti-2277	42	9	it	it	PRON
dti-2277	42	10	is	be	AUX
dti-2277	42	11	essential	essential	ADJ
dti-2277	42	12	for	for	ADP
dti-2277	42	13	peripheral	peripheral	ADJ
dti-2277	42	14	t	t	PROPN
dti-2277	42	15	cell	cell	NOUN
dti-2277	42	16	development	development	NOUN
dti-2277	42	17	(	(	PUNCT
dti-2277	42	18	tran	tran	PROPN
dti-2277	42	19	et	et	PROPN
dti-2277	42	20	al	al	PROPN
dti-2277	42	21	.	.	PROPN
dti-2277	42	22	2005	2005	NUM
dti-2277	42	23	)	)	PUNCT
dti-2277	42	24	.	.	PUNCT
dti-2277	43	1	however	however	ADV
dti-2277	43	2	,	,	PUNCT
dti-2277	43	3	the	the	DET
dti-2277	43	4	importance	importance	NOUN
dti-2277	43	5	of	of	ADP
dti-2277	43	6	cypb	cypb	NOUN
dti-2277	43	7	binding	bind	VERB
dti-2277	43	8	to	to	ADP
dti-2277	43	9	caml	caml	PROPN
dti-2277	43	10	function	function	NOUN
dti-2277	43	11	remains	remain	VERB
dti-2277	43	12	unknown	unknown	ADJ
dti-2277	43	13	.	.	PUNCT
dti-2277	44	1	cypb	cypb	PROPN
dti-2277	44	2	also	also	ADV
dti-2277	44	3	enhances	enhance	VERB
dti-2277	44	4	prolactin	prolactin	NOUN
dti-2277	44	5	-	-	PUNCT
dti-2277	44	6	driven	drive	VERB
dti-2277	44	7	cell	cell	NOUN
dti-2277	44	8	proliferation	proliferation	NOUN
dti-2277	44	9	(	(	PUNCT
dti-2277	44	10	rycyzyn	rycyzyn	NOUN
dti-2277	44	11	et	et	PROPN
dti-2277	44	12	al	al	PROPN
dti-2277	44	13	.	.	PROPN
dti-2277	44	14	2000	2000	NUM
dti-2277	44	15	)	)	PUNCT
dti-2277	44	16	and	and	CCONJ
dti-2277	44	17	promotes	promote	VERB
dti-2277	44	18	the	the	DET
dti-2277	44	19	nuclear	nuclear	ADJ
dti-2277	44	20	retrotranslocation	retrotranslocation	NOUN
dti-2277	44	21	of	of	ADP
dti-2277	44	22	prolactin	prolactin	NOUN
dti-2277	44	23	through	through	ADP
dti-2277	44	24	a	a	DET
dti-2277	44	25	direct	direct	ADJ
dti-2277	44	26	interaction	interaction	NOUN
dti-2277	44	27	.	.	PUNCT
dti-2277	45	1	additionally	additionally	ADV
dti-2277	45	2	,	,	PUNCT
dti-2277	45	3	cypb	cypb	NOUN
dti-2277	45	4	potentiates	potentiate	VERB
dti-2277	45	5	prolactin	prolactin	NOUN
dti-2277	45	6	-	-	PUNCT
dti-2277	45	7	induced	induce	VERB
dti-2277	45	8	stat5	stat5	NOUN
dti-2277	45	9	transactivation	transactivation	NOUN
dti-2277	45	10	by	by	ADP
dti-2277	45	11	promoting	promote	VERB
dti-2277	45	12	the	the	DET
dti-2277	45	13	dissociation	dissociation	NOUN
dti-2277	45	14	of	of	ADP
dti-2277	45	15	pias3	pias3	NOUN
dti-2277	45	16	,	,	PUNCT
dti-2277	45	17	a	a	DET
dti-2277	45	18	stat5	stat5	NOUN
dti-2277	45	19	repressor	repressor	NOUN
dti-2277	45	20	(	(	PUNCT
dti-2277	45	21	rycyzyn	rycyzyn	NOUN
dti-2277	45	22	and	and	CCONJ
dti-2277	45	23	clevenger	clevenger	PROPN
dti-2277	45	24	,	,	PUNCT
dti-2277	45	25	2002	2002	NUM
dti-2277	45	26	)	)	PUNCT
dti-2277	45	27	.	.	PUNCT
dti-2277	46	1	cypb	cypb	PROPN
dti-2277	46	2	can	can	AUX
dti-2277	46	3	also	also	ADV
dti-2277	46	4	associate	associate	VERB
dti-2277	46	5	with	with	ADP
dti-2277	46	6	interferon	interferon	ADJ
dti-2277	46	7	regulatory	regulatory	ADJ
dti-2277	46	8	factor	factor	NOUN
dti-2277	46	9	(	(	PUNCT
dti-2277	46	10	irf)-3	irf)-3	PROPN
dti-2277	46	11	(	(	PUNCT
dti-2277	46	12	obata	obata	PROPN
dti-2277	46	13	et	et	PROPN
dti-2277	46	14	al	al	PROPN
dti-2277	46	15	.	.	PROPN
dti-2277	46	16	2005	2005	NUM
dti-2277	46	17	)	)	PUNCT
dti-2277	46	18	.	.	PUNCT
dti-2277	47	1	extracellular	extracellular	ADJ
dti-2277	47	2	cypb	cypb	NOUN
dti-2277	47	3	can	can	AUX
dti-2277	47	4	bind	bind	VERB
dti-2277	47	5	platelets	platelet	NOUN
dti-2277	47	6	(	(	PUNCT
dti-2277	47	7	allain	allain	PROPN
dti-2277	47	8	et	et	PROPN
dti-2277	47	9	al	al	PROPN
dti-2277	47	10	.	.	PROPN
dti-2277	47	11	1999	1999	NUM
dti-2277	47	12	)	)	PUNCT
dti-2277	47	13	and	and	CCONJ
dti-2277	47	14	table	table	NOUN
dti-2277	47	15	1	1	NUM
dti-2277	47	16	.	.	PUNCT
dti-2277	48	1	human	human	ADJ
dti-2277	48	2	cyclophilin	cyclophilin	PROPN
dti-2277	48	3	subtypes	subtype	NOUN
dti-2277	48	4	.	.	PUNCT
dti-2277	49	1	protein	protein	NOUN
dti-2277	49	2	name	name	NOUN
dti-2277	49	3	length	length	NOUN
dti-2277	49	4	genbank	genbank	PROPN
dti-2277	49	5	accession	accession	NOUN
dti-2277	49	6	no	no	PROPN
dti-2277	49	7	.	.	PUNCT
dti-2277	50	1	reference	reference	NOUN
dti-2277	50	2	cypa	cypa	VERB
dti-2277	51	1	165	165	NUM
dti-2277	51	2	aa	aa	NOUN
dti-2277	51	3	nm_021130	nm_021130	PROPN
dti-2277	51	4	liu	liu	PROPN
dti-2277	51	5	et	et	PROPN
dti-2277	51	6	al	al	PROPN
dti-2277	51	7	.	.	PROPN
dti-2277	51	8	1990	1990	NUM
dti-2277	51	9	cypb	cypb	NOUN
dti-2277	51	10	216	216	NUM
dti-2277	51	11	aa	aa	NOUN
dti-2277	51	12	nm_000942	nm_000942	ADJ
dti-2277	51	13	price	price	NOUN
dti-2277	51	14	et	et	NOUN
dti-2277	51	15	al	al	PROPN
dti-2277	51	16	.	.	PROPN
dti-2277	51	17	1991	1991	NUM
dti-2277	51	18	cypc	cypc	VERB
dti-2277	51	19	212	212	NUM
dti-2277	51	20	aa	aa	PROPN
dti-2277	51	21	nm_000943	nm_000943	PROPN
dti-2277	51	22	friedman	friedman	PROPN
dti-2277	51	23	et	et	PROPN
dti-2277	51	24	al	al	PROPN
dti-2277	51	25	.	.	PROPN
dti-2277	51	26	1991	1991	NUM
dti-2277	52	1	cyp40	cyp40	ADJ
dti-2277	52	2	370	370	NUM
dti-2277	52	3	aa	aa	PROPN
dti-2277	52	4	nm_005038	nm_005038	PROPN
dti-2277	52	5	kieffer	kieffer	PROPN
dti-2277	52	6	et	et	PROPN
dti-2277	52	7	al	al	PROPN
dti-2277	52	8	.	.	PROPN
dti-2277	52	9	1992	1992	NUM
dti-2277	52	10	cype	cype	NOUN
dti-2277	52	11	,	,	PUNCT
dti-2277	52	12	cyp33	cyp33	NOUN
dti-2277	52	13	301	301	NUM
dti-2277	52	14	aa	aa	PROPN
dti-2277	52	15	nm_006112	nm_006112	PROPN
dti-2277	52	16	mi	mi	PROPN
dti-2277	52	17	et	et	PROPN
dti-2277	52	18	al	al	PROPN
dti-2277	52	19	.	.	PROPN
dti-2277	52	20	1996	1996	NUM
dti-2277	52	21	cypd	cypd	PROPN
dti-2277	52	22	,	,	PUNCT
dti-2277	52	23	cypf	cypf	NOUN
dti-2277	52	24	,	,	PUNCT
dti-2277	52	25	cyp3	cyp3	PROPN
dti-2277	52	26	207	207	NUM
dti-2277	52	27	aa	aa	PROPN
dti-2277	52	28	nm_005729	nm_005729	PROPN
dti-2277	52	29	bergsma	bergsma	PROPN
dti-2277	52	30	et	et	PROPN
dti-2277	52	31	al	al	PROPN
dti-2277	52	32	.	.	PROPN
dti-2277	52	33	1991	1991	NUM
dti-2277	52	34	cypg	cypg	NOUN
dti-2277	52	35	,	,	PUNCT
dti-2277	52	36	cars	car	NOUN
dti-2277	52	37	-	-	PUNCT
dti-2277	52	38	cyp	cyp	ADJ
dti-2277	52	39	,	,	PUNCT
dti-2277	52	40	srcyp	srcyp	NOUN
dti-2277	52	41	754	754	NUM
dti-2277	52	42	aa	aa	NOUN
dti-2277	52	43	nm_004792	nm_004792	ADJ
dti-2277	52	44	nestel	nestel	NOUN
dti-2277	52	45	et	et	PROPN
dti-2277	52	46	al	al	PROPN
dti-2277	52	47	.	.	PROPN
dti-2277	52	48	1996	1996	NUM
dti-2277	52	49	cyph	cyph	NOUN
dti-2277	52	50	,	,	PUNCT
dti-2277	52	51	usa	usa	NOUN
dti-2277	52	52	-	-	PUNCT
dti-2277	52	53	cyp	cyp	ADJ
dti-2277	52	54	,	,	PUNCT
dti-2277	52	55	snucyp-20	snucyp-20	PROPN
dti-2277	52	56	177	177	NUM
dti-2277	52	57	aa	aa	PROPN
dti-2277	52	58	nm_006347	nm_006347	PROPN
dti-2277	52	59	horowitz	horowitz	PROPN
dti-2277	52	60	et	et	PROPN
dti-2277	52	61	al	al	PROPN
dti-2277	52	62	.	.	PROPN
dti-2277	52	63	1997	1997	NUM
dti-2277	52	64	ppi	ppi	PROPN
dti-2277	52	65	-	-	PUNCT
dti-2277	52	66	l1	l1	PROPN
dti-2277	52	67	166	166	NUM
dti-2277	52	68	aa	aa	PROPN
dti-2277	52	69	nm_016059	nm_016059	PROPN
dti-2277	52	70	ozaki	ozaki	PROPN
dti-2277	52	71	et	et	PROPN
dti-2277	52	72	al	al	PROPN
dti-2277	52	73	.	.	PROPN
dti-2277	52	74	1996	1996	NUM
dti-2277	52	75	ppi	ppi	NOUN
dti-2277	52	76	-	-	PUNCT
dti-2277	52	77	l2	l2	NOUN
dti-2277	52	78	,	,	PUNCT
dti-2277	52	79	cyp60	cyp60	PROPN
dti-2277	52	80	520	520	NUM
dti-2277	52	81	aa	aa	NOUN
dti-2277	52	82	nm_014337	nm_014337	PROPN
dti-2277	52	83	wang	wang	PROPN
dti-2277	52	84	et	et	PROPN
dti-2277	52	85	al	al	PROPN
dti-2277	52	86	.	.	PROPN
dti-2277	52	87	1996	1996	NUM
dti-2277	52	88	ppil3	ppil3	NOUN
dti-2277	53	1	165	165	NUM
dti-2277	53	2	aa	aa	NOUN
dti-2277	53	3	nm_032472	nm_032472	PROPN
dti-2277	53	4	zhou	zhou	PROPN
dti-2277	53	5	et	et	PROPN
dti-2277	53	6	al	al	PROPN
dti-2277	53	7	.	.	PROPN
dti-2277	53	8	2001	2001	NUM
dti-2277	53	9	ppi	ppi	PROPN
dti-2277	53	10	-	-	PUNCT
dti-2277	53	11	l4	l4	PROPN
dti-2277	53	12	492	492	NUM
dti-2277	53	13	aa	aa	PROPN
dti-2277	53	14	nm_139126	nm_139126	PROPN
dti-2277	53	15	zeng	zeng	PROPN
dti-2277	53	16	et	et	PROPN
dti-2277	53	17	al	al	PROPN
dti-2277	53	18	.	.	PROPN
dti-2277	53	19	2001	2001	NUM
dti-2277	53	20	ppi	ppi	NOUN
dti-2277	53	21	-	-	PUNCT
dti-2277	53	22	l5	l5	ADJ
dti-2277	53	23	,	,	PUNCT
dti-2277	53	24	lrr-1	lrr-1	NUM
dti-2277	53	25	414	414	NUM
dti-2277	53	26	aa	aa	PROPN
dti-2277	53	27	nm_152329	nm_152329	PROPN
dti-2277	53	28	jang	jang	PROPN
dti-2277	53	29	et	et	PROPN
dti-2277	53	30	al	al	PROPN
dti-2277	53	31	.	.	PROPN
dti-2277	53	32	2001	2001	NUM
dti-2277	53	33	ranbp2	ranbp2	NOUN
dti-2277	53	34	3224	3224	NUM
dti-2277	53	35	aa	aa	NOUN
dti-2277	53	36	nm_006267	nm_006267	PROPN
dti-2277	53	37	yokoyama	yokoyama	PROPN
dti-2277	53	38	et	et	PROPN
dti-2277	53	39	al	al	PROPN
dti-2277	53	40	.	.	PROPN
dti-2277	53	41	1995	1995	NUM
dti-2277	53	42	drug	drug	NOUN
dti-2277	53	43	target	target	NOUN
dti-2277	53	44	insights	insight	NOUN
dti-2277	53	45	2007	2007	NUM
dti-2277	53	46	:	:	PUNCT
dti-2277	53	47	2	2	NUM
dti-2277	53	48	11	11	NUM
dti-2277	53	49	cyclophilin	cyclophilin	NOUN
dti-2277	53	50	and	and	CCONJ
dti-2277	53	51	viruses	virus	NOUN
dti-2277	53	52	this	this	PRON
dti-2277	53	53	initiates	initiate	VERB
dti-2277	53	54	a	a	DET
dti-2277	53	55	transmembranous	transmembranous	ADJ
dti-2277	53	56	infl	infl	PROPN
dti-2277	53	57	ux	ux	PROPN
dti-2277	53	58	of	of	ADP
dti-2277	53	59	calcium	calcium	NOUN
dti-2277	53	60	ion	ion	NOUN
dti-2277	53	61	,	,	PUNCT
dti-2277	53	62	kinase	kinase	NOUN
dti-2277	53	63	activation	activation	NOUN
dti-2277	53	64	,	,	PUNCT
dti-2277	53	65	and	and	CCONJ
dti-2277	53	66	platelet	platelet	NOUN
dti-2277	53	67	adhesion	adhesion	NOUN
dti-2277	53	68	to	to	ADP
dti-2277	53	69	collagen	collagen	NOUN
dti-2277	53	70	.	.	PUNCT
dti-2277	54	1	accumulating	accumulate	VERB
dti-2277	54	2	evidence	evidence	NOUN
dti-2277	54	3	suggests	suggest	VERB
dti-2277	54	4	that	that	SCONJ
dti-2277	54	5	cyps	cyps	PROPN
dti-2277	54	6	,	,	PUNCT
dti-2277	54	7	in	in	ADP
dti-2277	54	8	particular	particular	ADJ
dti-2277	54	9	cypa	cypa	PROPN
dti-2277	54	10	and	and	CCONJ
dti-2277	54	11	cypb	cypb	PROPN
dti-2277	54	12	,	,	PUNCT
dti-2277	54	13	can	can	AUX
dti-2277	54	14	mediate	mediate	VERB
dti-2277	54	15	intercellular	intercellular	ADJ
dti-2277	54	16	communication	communication	NOUN
dti-2277	54	17	similar	similar	ADJ
dti-2277	54	18	to	to	ADP
dti-2277	54	19	cytokines	cytokine	NOUN
dti-2277	54	20	.	.	PUNCT
dti-2277	55	1	cyps	cyps	PROPN
dti-2277	55	2	are	be	AUX
dti-2277	55	3	secreted	secrete	VERB
dti-2277	55	4	from	from	ADP
dti-2277	55	5	cells	cell	NOUN
dti-2277	55	6	in	in	ADP
dti-2277	55	7	response	response	NOUN
dti-2277	55	8	to	to	ADP
dti-2277	55	9	infl	infl	PROPN
dti-2277	55	10	ammatory	ammatory	NOUN
dti-2277	55	11	stimuli	stimulus	NOUN
dti-2277	55	12	or	or	CCONJ
dti-2277	55	13	oxidative	oxidative	ADJ
dti-2277	55	14	stress	stress	NOUN
dti-2277	55	15	(	(	PUNCT
dti-2277	55	16	jin	jin	NOUN
dti-2277	55	17	et	et	PROPN
dti-2277	55	18	al	al	PROPN
dti-2277	55	19	.	.	PROPN
dti-2277	55	20	2000	2000	NUM
dti-2277	55	21	;	;	PUNCT
dti-2277	55	22	seko	seko	NOUN
dti-2277	55	23	et	et	PROPN
dti-2277	55	24	al	al	PROPN
dti-2277	55	25	.	.	PROPN
dti-2277	55	26	2004	2004	NUM
dti-2277	55	27	;	;	PUNCT
dti-2277	56	1	sherry	sherry	PROPN
dti-2277	56	2	et	et	PROPN
dti-2277	56	3	al	al	PROPN
dti-2277	56	4	.	.	PROPN
dti-2277	56	5	1992	1992	NUM
dti-2277	56	6	;	;	PUNCT
dti-2277	56	7	xu	xu	PROPN
dti-2277	56	8	et	et	PROPN
dti-2277	56	9	al	al	PROPN
dti-2277	56	10	.	.	PROPN
dti-2277	56	11	1992	1992	NUM
dti-2277	56	12	)	)	PUNCT
dti-2277	56	13	and	and	CCONJ
dti-2277	56	14	they	they	PRON
dti-2277	56	15	can	can	AUX
dti-2277	56	16	act	act	VERB
dti-2277	56	17	as	as	ADP
dti-2277	56	18	potent	potent	ADJ
dti-2277	56	19	chemoattractants	chemoattractant	NOUN
dti-2277	56	20	for	for	ADP
dti-2277	56	21	neutrophils	neutrophil	NOUN
dti-2277	56	22	(	(	PUNCT
dti-2277	56	23	sherry	sherry	PROPN
dti-2277	56	24	et	et	PROPN
dti-2277	56	25	al	al	PROPN
dti-2277	56	26	.	.	PROPN
dti-2277	56	27	1992	1992	NUM
dti-2277	56	28	)	)	PUNCT
dti-2277	56	29	,	,	PUNCT
dti-2277	56	30	eosinophils	eosinophil	NOUN
dti-2277	56	31	(	(	PUNCT
dti-2277	56	32	xu	xu	INTJ
dti-2277	56	33	et	et	PROPN
dti-2277	56	34	al	al	PROPN
dti-2277	56	35	.	.	PROPN
dti-2277	56	36	1992	1992	NUM
dti-2277	56	37	)	)	PUNCT
dti-2277	56	38	,	,	PUNCT
dti-2277	56	39	and	and	CCONJ
dti-2277	56	40	t	t	PROPN
dti-2277	56	41	cells	cell	NOUN
dti-2277	56	42	(	(	PUNCT
dti-2277	56	43	allain	allain	PROPN
dti-2277	56	44	et	et	PROPN
dti-2277	56	45	al	al	PROPN
dti-2277	56	46	.	.	PROPN
dti-2277	56	47	2002	2002	NUM
dti-2277	56	48	)	)	PUNCT
dti-2277	56	49	.	.	PUNCT
dti-2277	57	1	cypa	cypa	PROPN
dti-2277	57	2	and	and	CCONJ
dti-2277	57	3	cypb	cypb	NOUN
dti-2277	57	4	are	be	AUX
dti-2277	57	5	recognized	recognize	VERB
dti-2277	57	6	by	by	ADP
dti-2277	57	7	the	the	DET
dti-2277	57	8	cell	cell	NOUN
dti-2277	57	9	surface	surface	NOUN
dti-2277	57	10	receptor	receptor	NOUN
dti-2277	57	11	cd147	cd147	PROPN
dti-2277	57	12	,	,	PUNCT
dti-2277	57	13	and	and	CCONJ
dti-2277	57	14	cyp	cyp	ADJ
dti-2277	57	15	binding	bind	VERB
dti-2277	57	16	leads	lead	NOUN
dti-2277	57	17	to	to	ADP
dti-2277	57	18	erk	erk	NOUN
dti-2277	57	19	activation	activation	NOUN
dti-2277	57	20	and	and	CCONJ
dti-2277	57	21	chemotaxis	chemotaxis	ADJ
dti-2277	57	22	(	(	PUNCT
dti-2277	57	23	pushkarsky	pushkarsky	NOUN
dti-2277	57	24	et	et	PROPN
dti-2277	57	25	al	al	PROPN
dti-2277	57	26	.	.	PROPN
dti-2277	57	27	2001	2001	NUM
dti-2277	57	28	;	;	PUNCT
dti-2277	57	29	yurchenko	yurchenko	PROPN
dti-2277	57	30	et	et	PROPN
dti-2277	57	31	al	al	PROPN
dti-2277	57	32	.	.	PROPN
dti-2277	57	33	2001	2001	NUM
dti-2277	57	34	;	;	PUNCT
dti-2277	57	35	yurchenko	yurchenko	PROPN
dti-2277	57	36	et	et	PROPN
dti-2277	57	37	al	al	PROPN
dti-2277	57	38	.	.	PROPN
dti-2277	57	39	2002	2002	NUM
dti-2277	57	40	)	)	PUNCT
dti-2277	57	41	.	.	PUNCT
dti-2277	58	1	cypd	cypd	PROPN
dti-2277	58	2	plays	play	VERB
dti-2277	58	3	a	a	DET
dti-2277	58	4	critical	critical	ADJ
dti-2277	58	5	role	role	NOUN
dti-2277	58	6	in	in	ADP
dti-2277	58	7	mitochondrial	mitochondrial	ADJ
dti-2277	58	8	function	function	NOUN
dti-2277	58	9	and	and	CCONJ
dti-2277	58	10	cell	cell	NOUN
dti-2277	58	11	death	death	NOUN
dti-2277	58	12	(	(	PUNCT
dti-2277	58	13	tanveer	tanveer	PROPN
dti-2277	58	14	et	et	PROPN
dti-2277	58	15	al	al	PROPN
dti-2277	58	16	.	.	PROPN
dti-2277	58	17	1996	1996	NUM
dti-2277	58	18	)	)	PUNCT
dti-2277	58	19	.	.	PUNCT
dti-2277	59	1	during	during	ADP
dti-2277	59	2	ischemia	ischemia	NOUN
dti-2277	59	3	-	-	PUNCT
dti-2277	59	4	induced	induce	VERB
dti-2277	59	5	necrosis	necrosis	NOUN
dti-2277	59	6	,	,	PUNCT
dti-2277	59	7	e.g.	e.g.	ADV
dti-2277	59	8	following	follow	VERB
dti-2277	59	9	a	a	DET
dti-2277	59	10	heart	heart	NOUN
dti-2277	59	11	attack	attack	NOUN
dti-2277	59	12	or	or	CCONJ
dti-2277	59	13	stroke	stroke	NOUN
dti-2277	59	14	,	,	PUNCT
dti-2277	59	15	the	the	DET
dti-2277	59	16	accumulation	accumulation	NOUN
dti-2277	59	17	of	of	ADP
dti-2277	59	18	calcium	calcium	NOUN
dti-2277	59	19	and	and	CCONJ
dti-2277	59	20	increase	increase	NOUN
dti-2277	59	21	of	of	ADP
dti-2277	59	22	reactive	reactive	ADJ
dti-2277	59	23	oxygen	oxygen	NOUN
dti-2277	59	24	species	specie	NOUN
dti-2277	59	25	(	(	PUNCT
dti-2277	59	26	ros	ros	PROPN
dti-2277	59	27	)	)	PUNCT
dti-2277	59	28	trigger	trigger	NOUN
dti-2277	59	29	the	the	DET
dti-2277	59	30	opening	opening	NOUN
dti-2277	59	31	of	of	ADP
dti-2277	59	32	a	a	DET
dti-2277	59	33	pore	pore	NOUN
dti-2277	59	34	in	in	ADP
dti-2277	59	35	the	the	DET
dti-2277	59	36	inner	inner	ADJ
dti-2277	59	37	mitochondrial	mitochondrial	ADJ
dti-2277	59	38	membrane	membrane	NOUN
dti-2277	59	39	,	,	PUNCT
dti-2277	59	40	known	know	VERB
dti-2277	59	41	as	as	ADP
dti-2277	59	42	the	the	DET
dti-2277	59	43	membrane	membrane	NOUN
dti-2277	59	44	permeability	permeability	NOUN
dti-2277	59	45	transition	transition	NOUN
dti-2277	59	46	pore	pore	ADJ
dti-2277	59	47	(	(	PUNCT
dti-2277	59	48	mptp	mptp	PROPN
dti-2277	59	49	)	)	PUNCT
dti-2277	59	50	(	(	PUNCT
dti-2277	59	51	halestrap	halestrap	NOUN
dti-2277	59	52	,	,	PUNCT
dti-2277	59	53	1999	1999	NUM
dti-2277	59	54	)	)	PUNCT
dti-2277	59	55	.	.	PUNCT
dti-2277	60	1	calcium	calcium	NOUN
dti-2277	60	2	overload	overload	NOUN
dti-2277	60	3	and	and	CCONJ
dti-2277	60	4	ros	ros	PROPN
dti-2277	60	5	induce	induce	VERB
dti-2277	60	6	a	a	DET
dti-2277	60	7	conformational	conformational	ADJ
dti-2277	60	8	change	change	NOUN
dti-2277	60	9	in	in	ADP
dti-2277	60	10	adenine	adenine	ADJ
dti-2277	60	11	nucleotide	nucleotide	NOUN
dti-2277	60	12	translocase	translocase	NOUN
dti-2277	60	13	(	(	PUNCT
dti-2277	60	14	ant	ant	NOUN
dti-2277	60	15	)	)	PUNCT
dti-2277	60	16	,	,	PUNCT
dti-2277	60	17	a	a	DET
dti-2277	60	18	key	key	ADJ
dti-2277	60	19	component	component	NOUN
dti-2277	60	20	regulating	regulate	VERB
dti-2277	60	21	the	the	DET
dti-2277	60	22	opening	opening	NOUN
dti-2277	60	23	of	of	ADP
dti-2277	60	24	mptp	mptp	NOUN
dti-2277	60	25	at	at	ADP
dti-2277	60	26	the	the	DET
dti-2277	60	27	inner	inner	ADJ
dti-2277	60	28	mitochondrial	mitochondrial	ADJ
dti-2277	60	29	membrane	membrane	NOUN
dti-2277	60	30	.	.	PUNCT
dti-2277	61	1	the	the	DET
dti-2277	61	2	opening	opening	NOUN
dti-2277	61	3	of	of	ADP
dti-2277	61	4	mptp	mptp	PROPN
dti-2277	61	5	leads	lead	VERB
dti-2277	61	6	to	to	ADP
dti-2277	61	7	mitochondrial	mitochondrial	ADJ
dti-2277	61	8	swelling	swelling	NOUN
dti-2277	61	9	,	,	PUNCT
dti-2277	61	10	rupture	rupture	NOUN
dti-2277	61	11	of	of	ADP
dti-2277	61	12	the	the	DET
dti-2277	61	13	outer	outer	ADJ
dti-2277	61	14	membrane	membrane	NOUN
dti-2277	61	15	,	,	PUNCT
dti-2277	61	16	and	and	CCONJ
dti-2277	61	17	the	the	DET
dti-2277	61	18	release	release	NOUN
dti-2277	61	19	of	of	ADP
dti-2277	61	20	small	small	ADJ
dti-2277	61	21	molecules	molecule	NOUN
dti-2277	61	22	(	(	PUNCT
dti-2277	61	23	waldmeier	waldmei	ADJ
dti-2277	61	24	et	et	PROPN
dti-2277	61	25	al	al	PROPN
dti-2277	61	26	.	.	PROPN
dti-2277	61	27	2003	2003	NUM
dti-2277	61	28	)	)	PUNCT
dti-2277	61	29	.	.	PUNCT
dti-2277	62	1	cypd	cypd	PROPN
dti-2277	62	2	is	be	AUX
dti-2277	62	3	located	locate	VERB
dti-2277	62	4	within	within	ADP
dti-2277	62	5	the	the	DET
dti-2277	62	6	matrix	matrix	NOUN
dti-2277	62	7	of	of	ADP
dti-2277	62	8	the	the	DET
dti-2277	62	9	mitochondria	mitochondria	NOUN
dti-2277	62	10	and	and	CCONJ
dti-2277	62	11	it	it	PRON
dti-2277	62	12	binds	bind	VERB
dti-2277	62	13	ant	ant	ADJ
dti-2277	62	14	facilitating	facilitate	VERB
dti-2277	62	15	its	its	PRON
dti-2277	62	16	conformational	conformational	ADJ
dti-2277	62	17	change	change	NOUN
dti-2277	62	18	(	(	PUNCT
dti-2277	62	19	crompton	crompton	PROPN
dti-2277	62	20	et	et	PROPN
dti-2277	62	21	al	al	PROPN
dti-2277	62	22	.	.	PROPN
dti-2277	62	23	1998	1998	NUM
dti-2277	62	24	;	;	PUNCT
dti-2277	62	25	woodfi	woodfi	VERB
dti-2277	62	26	eld	eld	PROPN
dti-2277	62	27	et	et	PROPN
dti-2277	62	28	al	al	PROPN
dti-2277	62	29	.	.	PROPN
dti-2277	62	30	1998	1998	NUM
dti-2277	62	31	)	)	PUNCT
dti-2277	62	32	.	.	PUNCT
dti-2277	63	1	in	in	ADP
dti-2277	63	2	cypd	cypd	PROPN
dti-2277	63	3	-	-	PUNCT
dti-2277	63	4	knockout	knockout	NOUN
dti-2277	63	5	cells	cell	NOUN
dti-2277	63	6	,	,	PUNCT
dti-2277	63	7	necrosis	necrosis	NOUN
dti-2277	63	8	induced	induce	VERB
dti-2277	63	9	by	by	ADP
dti-2277	63	10	calcium	calcium	NOUN
dti-2277	63	11	and	and	CCONJ
dti-2277	63	12	ros	ros	PROPN
dti-2277	63	13	was	be	AUX
dti-2277	63	14	decreased	decrease	VERB
dti-2277	63	15	,	,	PUNCT
dti-2277	63	16	but	but	CCONJ
dti-2277	63	17	apoptotic	apoptotic	ADJ
dti-2277	63	18	cell	cell	NOUN
dti-2277	63	19	death	death	NOUN
dti-2277	63	20	induced	induce	VERB
dti-2277	63	21	by	by	ADP
dti-2277	63	22	cytokines	cytokine	NOUN
dti-2277	63	23	or	or	CCONJ
dti-2277	63	24	anticancer	anticancer	NOUN
dti-2277	63	25	agents	agent	NOUN
dti-2277	63	26	was	be	AUX
dti-2277	63	27	unaffected	unaffected	ADJ
dti-2277	63	28	(	(	PUNCT
dti-2277	63	29	baines	baine	NOUN
dti-2277	63	30	et	et	PROPN
dti-2277	63	31	al	al	PROPN
dti-2277	63	32	.	.	PROPN
dti-2277	63	33	2005	2005	NUM
dti-2277	63	34	;	;	PUNCT
dti-2277	64	1	nakagawa	nakagawa	PROPN
dti-2277	64	2	et	et	PROPN
dti-2277	64	3	al	al	PROPN
dti-2277	64	4	.	.	PROPN
dti-2277	64	5	2005	2005	NUM
dti-2277	64	6	)	)	PUNCT
dti-2277	64	7	.	.	PUNCT
dti-2277	65	1	cypd	cypd	ADJ
dti-2277	65	2	-	-	PUNCT
dti-2277	65	3	knockout	knockout	NOUN
dti-2277	65	4	mice	mouse	NOUN
dti-2277	65	5	also	also	ADV
dti-2277	65	6	experienced	experience	VERB
dti-2277	65	7	reduced	reduced	ADJ
dti-2277	65	8	cardiac	cardiac	ADJ
dti-2277	65	9	injury	injury	NOUN
dti-2277	65	10	following	follow	VERB
dti-2277	65	11	reperfusion	reperfusion	NOUN
dti-2277	65	12	after	after	ADP
dti-2277	65	13	ischemia	ischemia	NOUN
dti-2277	65	14	.	.	PUNCT
dti-2277	66	1	thus	thus	ADV
dti-2277	66	2	,	,	PUNCT
dti-2277	66	3	cypd	cypd	PROPN
dti-2277	66	4	is	be	AUX
dti-2277	66	5	a	a	DET
dti-2277	66	6	key	key	ADJ
dti-2277	66	7	molecule	molecule	NOUN
dti-2277	66	8	involved	involve	VERB
dti-2277	66	9	in	in	ADP
dti-2277	66	10	the	the	DET
dti-2277	66	11	cell	cell	NOUN
dti-2277	66	12	death	death	NOUN
dti-2277	66	13	process	process	NOUN
dti-2277	66	14	.	.	PUNCT
dti-2277	67	1	cyp40	cyp40	PROPN
dti-2277	67	2	regulates	regulate	VERB
dti-2277	67	3	the	the	DET
dti-2277	67	4	activity	activity	NOUN
dti-2277	67	5	of	of	ADP
dti-2277	67	6	steroid	steroid	NOUN
dti-2277	67	7	receptors	receptor	NOUN
dti-2277	67	8	(	(	PUNCT
dti-2277	67	9	srs	srs	PROPN
dti-2277	67	10	)	)	PUNCT
dti-2277	67	11	(	(	PUNCT
dti-2277	67	12	duina	duina	NOUN
dti-2277	67	13	et	et	PROPN
dti-2277	67	14	al	al	PROPN
dti-2277	67	15	.	.	PROPN
dti-2277	67	16	1996	1996	NUM
dti-2277	67	17	;	;	PUNCT
dti-2277	67	18	owens	owens	PROPN
dti-2277	67	19	-	-	PUNCT
dti-2277	67	20	grillo	grillo	PROPN
dti-2277	67	21	et	et	PROPN
dti-2277	67	22	al	al	PROPN
dti-2277	67	23	.	.	PROPN
dti-2277	67	24	1995	1995	NUM
dti-2277	67	25	;	;	PUNCT
dti-2277	67	26	ratajczak	ratajczak	PROPN
dti-2277	67	27	et	et	PROPN
dti-2277	67	28	al	al	PROPN
dti-2277	67	29	.	.	PROPN
dti-2277	67	30	1993	1993	NUM
dti-2277	67	31	)	)	PUNCT
dti-2277	67	32	.	.	PUNCT
dti-2277	68	1	srs	srs	PROPN
dti-2277	68	2	including	include	VERB
dti-2277	68	3	the	the	DET
dti-2277	68	4	glucocorticoid	glucocorticoid	ADJ
dti-2277	68	5	receptor	receptor	NOUN
dti-2277	68	6	,	,	PUNCT
dti-2277	68	7	estrogen	estrogen	NOUN
dti-2277	68	8	receptor	receptor	NOUN
dti-2277	68	9	,	,	PUNCT
dti-2277	68	10	androgen	androgen	NOUN
dti-2277	68	11	receptor	receptor	NOUN
dti-2277	68	12	and	and	CCONJ
dti-2277	68	13	progesterone	progesterone	NOUN
dti-2277	68	14	receptor	receptor	NOUN
dti-2277	68	15	are	be	AUX
dti-2277	68	16	nuclear	nuclear	ADJ
dti-2277	68	17	hormone	hormone	NOUN
dti-2277	68	18	receptors	receptor	NOUN
dti-2277	68	19	that	that	PRON
dti-2277	68	20	exert	exert	VERB
dti-2277	68	21	transcriptional	transcriptional	ADJ
dti-2277	68	22	activity	activity	NOUN
dti-2277	68	23	following	follow	VERB
dti-2277	68	24	steroid	steroid	NOUN
dti-2277	68	25	ligand	ligand	NOUN
dti-2277	68	26	binding	bind	VERB
dti-2277	68	27	and	and	CCONJ
dti-2277	68	28	nuclear	nuclear	ADJ
dti-2277	68	29	translocation	translocation	NOUN
dti-2277	68	30	.	.	PUNCT
dti-2277	69	1	in	in	ADP
dti-2277	69	2	the	the	DET
dti-2277	69	3	absence	absence	NOUN
dti-2277	69	4	of	of	ADP
dti-2277	69	5	steroid	steroid	NOUN
dti-2277	69	6	ligands	ligand	NOUN
dti-2277	69	7	,	,	PUNCT
dti-2277	69	8	srs	srs	PROPN
dti-2277	69	9	form	form	NOUN
dti-2277	69	10	complexes	complexe	VERB
dti-2277	69	11	with	with	ADP
dti-2277	69	12	heat	heat	NOUN
dti-2277	69	13	shock	shock	NOUN
dti-2277	69	14	protein	protein	NOUN
dti-2277	69	15	90	90	NUM
dti-2277	69	16	(	(	PUNCT
dti-2277	69	17	hsp90	hsp90	NOUN
dti-2277	69	18	)	)	PUNCT
dti-2277	69	19	together	together	ADV
dti-2277	69	20	with	with	ADP
dti-2277	69	21	the	the	DET
dti-2277	69	22	immunophilins	immunophilin	NOUN
dti-2277	69	23	cyp40	cyp40	ADJ
dti-2277	69	24	,	,	PUNCT
dti-2277	69	25	fkbp51	fkbp51	NOUN
dti-2277	69	26	,	,	PUNCT
dti-2277	69	27	or	or	CCONJ
dti-2277	69	28	fkbp52	fkbp52	NOUN
dti-2277	69	29	in	in	ADP
dti-2277	69	30	the	the	DET
dti-2277	69	31	cytoplasm	cytoplasm	NOUN
dti-2277	69	32	.	.	PUNCT
dti-2277	70	1	these	these	DET
dti-2277	70	2	immunophilins	immunophilin	NOUN
dti-2277	70	3	control	control	VERB
dti-2277	70	4	sr	sr	PROPN
dti-2277	70	5	activity	activity	NOUN
dti-2277	70	6	by	by	ADP
dti-2277	70	7	increasing	increase	VERB
dti-2277	70	8	receptor	receptor	NOUN
dti-2277	70	9	avidity	avidity	NOUN
dti-2277	70	10	for	for	ADP
dti-2277	70	11	hormone	hormone	NOUN
dti-2277	70	12	ligands	ligand	NOUN
dti-2277	70	13	through	through	ADP
dti-2277	70	14	ppiase	ppiase	NOUN
dti-2277	70	15	-	-	PUNCT
dti-2277	70	16	dependent	dependent	ADJ
dti-2277	70	17	conformational	conformational	ADJ
dti-2277	70	18	changes	change	NOUN
dti-2277	70	19	.	.	PUNCT
dti-2277	71	1	upon	upon	SCONJ
dti-2277	71	2	hormone	hormone	NOUN
dti-2277	71	3	binding	bind	VERB
dti-2277	71	4	,	,	PUNCT
dti-2277	71	5	this	this	PRON
dti-2277	71	6	sr	sr	PROPN
dti-2277	71	7	/	/	SYM
dti-2277	71	8	hsp90/	hsp90/	PROPN
dti-2277	71	9	immunophilin	immunophilin	NOUN
dti-2277	71	10	complex	complex	ADJ
dti-2277	71	11	dissociates	dissociate	NOUN
dti-2277	71	12	,	,	PUNCT
dti-2277	71	13	leaving	leave	VERB
dti-2277	71	14	homodimeric	homodimeric	PROPN
dti-2277	71	15	sr	sr	PROPN
dti-2277	71	16	,	,	PUNCT
dti-2277	71	17	which	which	PRON
dti-2277	71	18	then	then	ADV
dti-2277	71	19	translocates	translocate	VERB
dti-2277	71	20	into	into	ADP
dti-2277	71	21	the	the	DET
dti-2277	71	22	nucleus	nucleus	NOUN
dti-2277	71	23	to	to	PART
dti-2277	71	24	transactivate	transactivate	VERB
dti-2277	71	25	downstream	downstream	ADJ
dti-2277	71	26	genes	gene	NOUN
dti-2277	71	27	.	.	PUNCT
dti-2277	72	1	although	although	SCONJ
dti-2277	72	2	there	there	PRON
dti-2277	72	3	are	be	VERB
dti-2277	72	4	some	some	DET
dti-2277	72	5	reports	report	NOUN
dti-2277	72	6	on	on	ADP
dti-2277	72	7	other	other	ADJ
dti-2277	72	8	cyp	cyp	ADJ
dti-2277	72	9	subtypes	subtype	NOUN
dti-2277	72	10	(	(	PUNCT
dti-2277	72	11	table	table	NOUN
dti-2277	72	12	1	1	NUM
dti-2277	72	13	)	)	PUNCT
dti-2277	72	14	,	,	PUNCT
dti-2277	72	15	the	the	DET
dti-2277	72	16	precise	precise	ADJ
dti-2277	72	17	functions	function	NOUN
dti-2277	72	18	and	and	CCONJ
dti-2277	72	19	signifi	signifi	NOUN
dti-2277	72	20	cances	cance	NOUN
dti-2277	72	21	of	of	ADP
dti-2277	72	22	them	they	PRON
dti-2277	72	23	are	be	AUX
dti-2277	72	24	largely	largely	ADV
dti-2277	72	25	unknown	unknown	ADJ
dti-2277	72	26	.	.	PUNCT
dti-2277	73	1	viruses	virus	NOUN
dti-2277	73	2	requiring	require	VERB
dti-2277	73	3	cyps	cyp	NOUN
dti-2277	73	4	as	as	SCONJ
dti-2277	73	5	described	describe	VERB
dti-2277	73	6	above	above	ADV
dti-2277	73	7	,	,	PUNCT
dti-2277	73	8	cyps	cyps	PROPN
dti-2277	73	9	play	play	VERB
dti-2277	73	10	essential	essential	ADJ
dti-2277	73	11	roles	role	NOUN
dti-2277	73	12	in	in	ADP
dti-2277	73	13	diverse	diverse	ADJ
dti-2277	73	14	cellular	cellular	ADJ
dti-2277	73	15	processes	process	NOUN
dti-2277	73	16	.	.	PUNCT
dti-2277	74	1	interestingly	interestingly	ADV
dti-2277	74	2	,	,	PUNCT
dti-2277	74	3	several	several	ADJ
dti-2277	74	4	viruses	virus	NOUN
dti-2277	74	5	have	have	AUX
dti-2277	74	6	evolved	evolve	VERB
dti-2277	74	7	to	to	PART
dti-2277	74	8	use	use	VERB
dti-2277	74	9	cyps	cyp	NOUN
dti-2277	74	10	during	during	ADP
dti-2277	74	11	their	their	PRON
dti-2277	74	12	life	life	NOUN
dti-2277	74	13	cycles	cycle	NOUN
dti-2277	74	14	.	.	PUNCT
dti-2277	75	1	in	in	ADP
dti-2277	75	2	particular	particular	ADJ
dti-2277	75	3	,	,	PUNCT
dti-2277	75	4	cyps	cyps	PROPN
dti-2277	75	5	are	be	AUX
dti-2277	75	6	demonstrated	demonstrate	VERB
dti-2277	75	7	to	to	PART
dti-2277	75	8	be	be	AUX
dti-2277	75	9	involved	involve	VERB
dti-2277	75	10	in	in	ADP
dti-2277	75	11	the	the	DET
dti-2277	75	12	proliferation	proliferation	NOUN
dti-2277	75	13	of	of	ADP
dti-2277	75	14	hiv-1	hiv-1	PUNCT
dti-2277	75	15	and	and	CCONJ
dti-2277	75	16	hepatitis	hepatitis	PROPN
dti-2277	75	17	c	c	PROPN
dti-2277	75	18	virus	virus	NOUN
dti-2277	75	19	(	(	PUNCT
dti-2277	75	20	hcv	hcv	PROPN
dti-2277	75	21	)	)	PUNCT
dti-2277	75	22	.	.	PUNCT
dti-2277	76	1	other	other	ADJ
dti-2277	76	2	viruses	virus	NOUN
dti-2277	76	3	using	use	VERB
dti-2277	76	4	cyps	cyp	NOUN
dti-2277	76	5	during	during	ADP
dti-2277	76	6	their	their	PRON
dti-2277	76	7	life	life	NOUN
dti-2277	76	8	cycle	cycle	NOUN
dti-2277	76	9	include	include	VERB
dti-2277	76	10	vaccinia	vaccinia	NOUN
dti-2277	76	11	virus	virus	NOUN
dti-2277	76	12	(	(	PUNCT
dti-2277	76	13	vv	vv	NOUN
dti-2277	76	14	)	)	PUNCT
dti-2277	76	15	,	,	PUNCT
dti-2277	76	16	vesicular	vesicular	ADJ
dti-2277	76	17	stomatitis	stomatitis	PROPN
dti-2277	76	18	virus	virus	NOUN
dti-2277	76	19	(	(	PUNCT
dti-2277	76	20	vsv	vsv	PROPN
dti-2277	76	21	)	)	PUNCT
dti-2277	76	22	,	,	PUNCT
dti-2277	76	23	and	and	CCONJ
dti-2277	76	24	sars	sar	NOUN
dti-2277	76	25	-	-	PUNCT
dti-2277	76	26	coronavirus	coronavirus	NOUN
dti-2277	76	27	.	.	PUNCT
dti-2277	77	1	vaccinia	vaccinia	NOUN
dti-2277	77	2	virus	virus	PROPN
dti-2277	77	3	a	a	DET
dti-2277	77	4	signifi	signifi	NOUN
dti-2277	77	5	ca	can	AUX
dti-2277	77	6	nt	not	PART
dti-2277	77	7	role	role	VERB
dti-2277	77	8	of	of	ADP
dti-2277	77	9	cyp	cyp	ADJ
dti-2277	77	10	in	in	ADP
dti-2277	77	11	vv	vv	ADP
dti-2277	77	12	replication	replication	NOUN
dti-2277	77	13	was	be	AUX
dti-2277	77	14	fi	fi	NOUN
dti-2277	77	15	rst	rst	PROPN
dti-2277	77	16	identifi	identifi	PROPN
dti-2277	77	17	ed	ed	NOUN
dti-2277	77	18	through	through	ADP
dti-2277	77	19	the	the	DET
dti-2277	77	20	analysis	analysis	NOUN
dti-2277	77	21	of	of	ADP
dti-2277	77	22	several	several	ADJ
dti-2277	77	23	csa	csa	PROPN
dti-2277	77	24	analogs	analog	NOUN
dti-2277	77	25	.	.	PUNCT
dti-2277	78	1	the	the	DET
dti-2277	78	2	ability	ability	NOUN
dti-2277	78	3	of	of	ADP
dti-2277	78	4	cyclosporins	cyclosporin	NOUN
dti-2277	78	5	to	to	PART
dti-2277	78	6	suppress	suppress	VERB
dti-2277	78	7	vv	vv	ADP
dti-2277	78	8	replication	replication	NOUN
dti-2277	78	9	correlated	correlate	VERB
dti-2277	78	10	with	with	ADP
dti-2277	78	11	the	the	DET
dti-2277	78	12	inhibition	inhibition	NOUN
dti-2277	78	13	of	of	ADP
dti-2277	78	14	cyp	cyp	ADJ
dti-2277	78	15	function	function	NOUN
dti-2277	78	16	(	(	PUNCT
dti-2277	78	17	damaso	damaso	NOUN
dti-2277	78	18	and	and	CCONJ
dti-2277	78	19	moussatche	moussatche	NOUN
dti-2277	78	20	,	,	PUNCT
dti-2277	78	21	1998	1998	NUM
dti-2277	78	22	)	)	PUNCT
dti-2277	78	23	.	.	PUNCT
dti-2277	79	1	vv	vv	ADP
dti-2277	79	2	infection	infection	NOUN
dti-2277	79	3	stabilizes	stabilize	VERB
dti-2277	79	4	cypa	cypa	PROPN
dti-2277	79	5	,	,	PUNCT
dti-2277	79	6	leading	lead	VERB
dti-2277	79	7	to	to	ADP
dti-2277	79	8	the	the	DET
dti-2277	79	9	accumulation	accumulation	NOUN
dti-2277	79	10	of	of	ADP
dti-2277	79	11	cypa	cypa	PROPN
dti-2277	79	12	(	(	PUNCT
dti-2277	79	13	castro	castro	VERB
dti-2277	79	14	et	et	PROPN
dti-2277	79	15	al	al	PROPN
dti-2277	79	16	.	.	PROPN
dti-2277	79	17	2003	2003	NUM
dti-2277	79	18	)	)	PUNCT
dti-2277	79	19	.	.	PUNCT
dti-2277	80	1	in	in	ADP
dti-2277	80	2	vv	vv	ADP
dti-2277	80	3	infected	infected	ADJ
dti-2277	80	4	cells	cell	NOUN
dti-2277	80	5	,	,	PUNCT
dti-2277	80	6	cypa	cypa	PROPN
dti-2277	80	7	relocalizes	relocalize	VERB
dti-2277	80	8	to	to	ADP
dti-2277	80	9	the	the	DET
dti-2277	80	10	peripheral	peripheral	ADJ
dti-2277	80	11	region	region	NOUN
dti-2277	80	12	of	of	ADP
dti-2277	80	13	the	the	DET
dti-2277	80	14	nucleus	nucleus	NOUN
dti-2277	80	15	,	,	PUNCT
dti-2277	80	16	colocalizing	colocalize	VERB
dti-2277	80	17	with	with	ADP
dti-2277	80	18	sites	site	NOUN
dti-2277	80	19	of	of	ADP
dti-2277	80	20	virus	virus	NOUN
dti-2277	80	21	production	production	NOUN
dti-2277	80	22	.	.	PUNCT
dti-2277	81	1	cypa	cypa	PROPN
dti-2277	81	2	is	be	AUX
dti-2277	81	3	incorporated	incorporate	VERB
dti-2277	81	4	into	into	ADP
dti-2277	81	5	viral	viral	ADJ
dti-2277	81	6	particles	particle	NOUN
dti-2277	81	7	and	and	CCONJ
dti-2277	81	8	is	be	AUX
dti-2277	81	9	located	locate	VERB
dti-2277	81	10	in	in	ADP
dti-2277	81	11	the	the	DET
dti-2277	81	12	viral	viral	ADJ
dti-2277	81	13	core	core	NOUN
dti-2277	81	14	.	.	PUNCT
dti-2277	82	1	vesicular	vesicular	ADJ
dti-2277	82	2	stomatitis	stomatitis	PROPN
dti-2277	82	3	virus	virus	NOUN
dti-2277	82	4	cypa	cypa	PROPN
dti-2277	82	5	interacted	interact	VERB
dti-2277	82	6	with	with	ADP
dti-2277	82	7	the	the	DET
dti-2277	82	8	nucleocapsid	nucleocapsid	ADJ
dti-2277	82	9	protein	protein	NOUN
dti-2277	82	10	of	of	ADP
dti-2277	82	11	vsv	vsv	PROPN
dti-2277	82	12	(	(	PUNCT
dti-2277	82	13	bose	bose	PROPN
dti-2277	82	14	et	et	PROPN
dti-2277	82	15	al	al	PROPN
dti-2277	82	16	.	.	PROPN
dti-2277	82	17	2003	2003	NUM
dti-2277	82	18	)	)	PUNCT
dti-2277	82	19	,	,	PUNCT
dti-2277	82	20	and	and	CCONJ
dti-2277	82	21	,	,	PUNCT
dti-2277	82	22	like	like	ADP
dti-2277	82	23	vv	vv	VERB
dti-2277	82	24	,	,	PUNCT
dti-2277	82	25	cypa	cypa	PROPN
dti-2277	82	26	is	be	AUX
dti-2277	82	27	incorporated	incorporate	VERB
dti-2277	82	28	into	into	ADP
dti-2277	82	29	vsv	vsv	PROPN
dti-2277	82	30	viral	viral	ADJ
dti-2277	82	31	particles	particle	NOUN
dti-2277	82	32	.	.	PUNCT
dti-2277	83	1	although	although	SCONJ
dti-2277	83	2	the	the	DET
dti-2277	83	3	binding	binding	NOUN
dti-2277	83	4	and	and	CCONJ
dti-2277	83	5	incorporation	incorporation	NOUN
dti-2277	83	6	of	of	ADP
dti-2277	83	7	cypa	cypa	NOUN
dti-2277	83	8	occurred	occur	VERB
dti-2277	83	9	beyond	beyond	ADP
dti-2277	83	10	the	the	DET
dti-2277	83	11	virus	virus	NOUN
dti-2277	83	12	serotypes	serotype	NOUN
dti-2277	83	13	,	,	PUNCT
dti-2277	83	14	the	the	DET
dti-2277	83	15	functional	functional	ADJ
dti-2277	83	16	role	role	NOUN
dti-2277	83	17	of	of	ADP
dti-2277	83	18	cypa	cypa	PROPN
dti-2277	83	19	in	in	ADP
dti-2277	83	20	the	the	DET
dti-2277	83	21	viral	viral	ADJ
dti-2277	83	22	life	life	NOUN
dti-2277	83	23	cycle	cycle	NOUN
dti-2277	83	24	appears	appear	VERB
dti-2277	83	25	to	to	PART
dti-2277	83	26	be	be	AUX
dti-2277	83	27	straindependent	straindependent	NOUN
dti-2277	83	28	.	.	PUNCT
dti-2277	84	1	inhibition	inhibition	NOUN
dti-2277	84	2	of	of	ADP
dti-2277	84	3	cyp	cyp	ADJ
dti-2277	84	4	activity	activity	NOUN
dti-2277	84	5	by	by	ADP
dti-2277	84	6	csa	csa	PROPN
dti-2277	84	7	reduced	reduce	VERB
dti-2277	84	8	primary	primary	ADJ
dti-2277	84	9	transcription	transcription	NOUN
dti-2277	84	10	of	of	ADP
dti-2277	84	11	vsv	vsv	PROPN
dti-2277	84	12	-	-	PUNCT
dti-2277	84	13	new	new	PROPN
dti-2277	84	14	jersey	jersey	PROPN
dti-2277	84	15	(	(	PUNCT
dti-2277	84	16	vsv	vsv	PROPN
dti-2277	84	17	-	-	PUNCT
dti-2277	84	18	nj	nj	PROPN
dti-2277	84	19	)	)	PUNCT
dti-2277	84	20	but	but	CCONJ
dti-2277	84	21	not	not	PART
dti-2277	84	22	vsv	vsv	PROPN
dti-2277	84	23	-	-	PUNCT
dti-2277	84	24	indiana	indiana	PROPN
dti-2277	84	25	(	(	PUNCT
dti-2277	84	26	vsv	vsv	PROPN
dti-2277	84	27	-	-	PUNCT
dti-2277	84	28	ind	ind	ADJ
dti-2277	84	29	)	)	PUNCT
dti-2277	84	30	serotype	serotype	NOUN
dti-2277	84	31	,	,	PUNCT
dti-2277	84	32	and	and	CCONJ
dti-2277	84	33	cypa	cypa	ADJ
dti-2277	84	34	activity	activity	NOUN
dti-2277	84	35	was	be	AUX
dti-2277	84	36	required	require	VERB
dti-2277	84	37	for	for	ADP
dti-2277	84	38	the	the	DET
dti-2277	84	39	replication	replication	NOUN
dti-2277	84	40	of	of	ADP
dti-2277	84	41	vsv	vsv	PROPN
dti-2277	84	42	-	-	PUNCT
dti-2277	84	43	nj	nj	PROPN
dti-2277	84	44	to	to	ADP
dti-2277	84	45	a	a	DET
dti-2277	84	46	greater	great	ADJ
dti-2277	84	47	extent	extent	NOUN
dti-2277	84	48	than	than	ADP
dti-2277	84	49	vsv	vsv	PROPN
dti-2277	84	50	-	-	PUNCT
dti-2277	84	51	ind	ind	NOUN
dti-2277	84	52	.	.	PUNCT
dti-2277	85	1	the	the	DET
dti-2277	85	2	authors	author	NOUN
dti-2277	85	3	suggest	suggest	VERB
dti-2277	85	4	that	that	SCONJ
dti-2277	85	5	differential	differential	ADJ
dti-2277	85	6	requirements	requirement	NOUN
dti-2277	85	7	of	of	ADP
dti-2277	85	8	cypa	cypa	PROPN
dti-2277	85	9	are	be	AUX
dti-2277	85	10	likely	likely	ADJ
dti-2277	85	11	the	the	DET
dti-2277	85	12	results	result	NOUN
dti-2277	85	13	of	of	ADP
dti-2277	85	14	evolutionary	evolutionary	ADJ
dti-2277	85	15	pressure	pressure	NOUN
dti-2277	85	16	during	during	ADP
dti-2277	85	17	lineage	lineage	NOUN
dti-2277	85	18	development	development	NOUN
dti-2277	85	19	.	.	PUNCT
dti-2277	86	1	drug	drug	NOUN
dti-2277	86	2	target	target	NOUN
dti-2277	86	3	insights	insight	NOUN
dti-2277	86	4	2007	2007	NUM
dti-2277	86	5	:	:	PUNCT
dti-2277	86	6	2	2	NUM
dti-2277	86	7	12	12	NUM
dti-2277	86	8	watashi	watashi	NOUN
dti-2277	86	9	and	and	CCONJ
dti-2277	86	10	shimotohno	shimotohno	NOUN
dti-2277	86	11	sars	sars	PROPN
dti-2277	86	12	coronavirus	coronavirus	VERB
dti-2277	86	13	the	the	DET
dti-2277	86	14	nucleocapsid	nucleocapsid	ADJ
dti-2277	86	15	protein	protein	NOUN
dti-2277	86	16	(	(	PUNCT
dti-2277	86	17	np	np	INTJ
dti-2277	86	18	)	)	PUNCT
dti-2277	86	19	of	of	ADP
dti-2277	86	20	severe	severe	ADJ
dti-2277	86	21	acute	acute	ADJ
dti-2277	86	22	respiratory	respiratory	ADJ
dti-2277	86	23	syndrome	syndrome	NOUN
dti-2277	86	24	coronavirus	coronavirus	NOUN
dti-2277	86	25	(	(	PUNCT
dti-2277	86	26	sars	sars	PROPN
dti-2277	86	27	-	-	PUNCT
dti-2277	86	28	cov	cov	NOUN
dti-2277	86	29	)	)	PUNCT
dti-2277	86	30	binds	bind	VERB
dti-2277	86	31	cypa	cypa	PROPN
dti-2277	86	32	(	(	PUNCT
dti-2277	86	33	luo	luo	PROPN
dti-2277	86	34	et	et	PROPN
dti-2277	86	35	al	al	PROPN
dti-2277	86	36	.	.	PROPN
dti-2277	86	37	2004	2004	NUM
dti-2277	86	38	)	)	PUNCT
dti-2277	86	39	,	,	PUNCT
dti-2277	86	40	and	and	CCONJ
dti-2277	86	41	another	another	DET
dti-2277	86	42	group	group	NOUN
dti-2277	86	43	reported	report	VERB
dti-2277	86	44	that	that	SCONJ
dti-2277	86	45	cypa	cypa	PROPN
dti-2277	86	46	is	be	AUX
dti-2277	86	47	incorporated	incorporate	VERB
dti-2277	86	48	into	into	ADP
dti-2277	86	49	sars	sar	NOUN
dti-2277	86	50	-	-	PUNCT
dti-2277	86	51	cov	cov	NOUN
dti-2277	86	52	particles	particle	NOUN
dti-2277	86	53	(	(	PUNCT
dti-2277	86	54	chen	chen	PROPN
dti-2277	86	55	et	et	PROPN
dti-2277	86	56	al	al	PROPN
dti-2277	86	57	.	.	PROPN
dti-2277	86	58	2005	2005	NUM
dti-2277	86	59	)	)	PUNCT
dti-2277	86	60	.	.	PUNCT
dti-2277	87	1	extracellular	extracellular	ADJ
dti-2277	87	2	cypa	cypa	PROPN
dti-2277	87	3	binds	bind	VERB
dti-2277	87	4	cd147	cd147	PROPN
dti-2277	87	5	on	on	ADP
dti-2277	87	6	the	the	DET
dti-2277	87	7	cell	cell	NOUN
dti-2277	87	8	surface	surface	NOUN
dti-2277	87	9	,	,	PUNCT
dti-2277	87	10	and	and	CCONJ
dti-2277	87	11	treatment	treatment	NOUN
dti-2277	87	12	with	with	ADP
dti-2277	87	13	a	a	DET
dti-2277	87	14	peptide	peptide	NOUN
dti-2277	87	15	that	that	PRON
dti-2277	87	16	blocks	block	VERB
dti-2277	87	17	cd147	cd147	PROPN
dti-2277	87	18	binding	bind	VERB
dti-2277	87	19	inhibits	inhibit	VERB
dti-2277	87	20	viral	viral	ADJ
dti-2277	87	21	infection	infection	NOUN
dti-2277	87	22	.	.	PUNCT
dti-2277	88	1	thus	thus	ADV
dti-2277	88	2	,	,	PUNCT
dti-2277	88	3	cypa	cypa	PROPN
dti-2277	88	4	may	may	AUX
dti-2277	88	5	be	be	AUX
dti-2277	88	6	involved	involve	VERB
dti-2277	88	7	in	in	ADP
dti-2277	88	8	sars	sar	NOUN
dti-2277	88	9	-	-	PUNCT
dti-2277	88	10	cov	cov	NOUN
dti-2277	88	11	invasion	invasion	NOUN
dti-2277	88	12	into	into	ADP
dti-2277	88	13	host	host	NOUN
dti-2277	88	14	cells	cell	NOUN
dti-2277	88	15	through	through	ADP
dti-2277	88	16	interaction	interaction	NOUN
dti-2277	88	17	with	with	ADP
dti-2277	88	18	np	np	INTJ
dti-2277	88	19	and	and	CCONJ
dti-2277	88	20	cd147	cd147	PROPN
dti-2277	88	21	,	,	PUNCT
dti-2277	88	22	respectively	respectively	ADV
dti-2277	88	23	.	.	PUNCT
dti-2277	89	1	cypa	cypa	PROPN
dti-2277	89	2	and	and	CCONJ
dti-2277	89	3	hiv-1	hiv-1	X
dti-2277	89	4	cypa	cypa	PROPN
dti-2277	89	5	plays	play	VERB
dti-2277	89	6	an	an	DET
dti-2277	89	7	important	important	ADJ
dti-2277	89	8	role	role	NOUN
dti-2277	89	9	in	in	ADP
dti-2277	89	10	the	the	DET
dti-2277	89	11	viral	viral	ADJ
dti-2277	89	12	life	life	NOUN
dti-2277	89	13	cycle	cycle	NOUN
dti-2277	89	14	of	of	ADP
dti-2277	89	15	hiv-1	hiv-1	X
dti-2277	89	16	.	.	PUNCT
dti-2277	90	1	in	in	ADP
dti-2277	90	2	1993	1993	NUM
dti-2277	90	3	,	,	PUNCT
dti-2277	90	4	cypa	cypa	PROPN
dti-2277	90	5	was	be	AUX
dti-2277	90	6	found	find	VERB
dti-2277	90	7	to	to	PART
dti-2277	90	8	interact	interact	VERB
dti-2277	90	9	with	with	ADP
dti-2277	90	10	hiv-1	hiv-1	PUNCT
dti-2277	90	11	gag	gag	NOUN
dti-2277	90	12	(	(	PUNCT
dti-2277	90	13	luban	luban	PROPN
dti-2277	90	14	et	et	PROPN
dti-2277	90	15	al	al	PROPN
dti-2277	90	16	.	.	PROPN
dti-2277	90	17	1993	1993	NUM
dti-2277	90	18	)	)	PUNCT
dti-2277	90	19	,	,	PUNCT
dti-2277	90	20	and	and	CCONJ
dti-2277	90	21	in	in	ADP
dti-2277	90	22	1994	1994	NUM
dti-2277	90	23	,	,	PUNCT
dti-2277	90	24	cypa	cypa	PROPN
dti-2277	90	25	was	be	AUX
dti-2277	90	26	reportedly	reportedly	ADV
dti-2277	90	27	incorporated	incorporate	VERB
dti-2277	90	28	into	into	ADP
dti-2277	90	29	viral	viral	ADJ
dti-2277	90	30	particles	particle	NOUN
dti-2277	90	31	(	(	PUNCT
dti-2277	90	32	franke	franke	PROPN
dti-2277	90	33	et	et	PROPN
dti-2277	90	34	al	al	PROPN
dti-2277	90	35	.	.	PROPN
dti-2277	90	36	1994	1994	NUM
dti-2277	90	37	;	;	PUNCT
dti-2277	90	38	thali	thali	PROPN
dti-2277	90	39	et	et	PROPN
dti-2277	90	40	al	al	PROPN
dti-2277	90	41	.	.	PROPN
dti-2277	90	42	1994	1994	NUM
dti-2277	90	43	)	)	PUNCT
dti-2277	90	44	.	.	PUNCT
dti-2277	91	1	a	a	DET
dti-2277	91	2	gene	gene	NOUN
dti-2277	91	3	targeting	target	VERB
dti-2277	91	4	study	study	NOUN
dti-2277	91	5	demonstrated	demonstrate	VERB
dti-2277	91	6	that	that	SCONJ
dti-2277	91	7	only	only	ADV
dti-2277	91	8	cypa	cypa	X
dti-2277	91	9	among	among	ADP
dti-2277	91	10	cyp	cyp	ADJ
dti-2277	91	11	subtypes	subtype	NOUN
dti-2277	91	12	was	be	AUX
dti-2277	91	13	essential	essential	ADJ
dti-2277	91	14	for	for	ADP
dti-2277	91	15	hiv-1	hiv-1	PUNCT
dti-2277	91	16	proliferation	proliferation	NOUN
dti-2277	91	17	(	(	PUNCT
dti-2277	91	18	braaten	braaten	ADJ
dti-2277	91	19	and	and	CCONJ
dti-2277	91	20	luban	luban	ADJ
dti-2277	91	21	,	,	PUNCT
dti-2277	91	22	2001	2001	NUM
dti-2277	91	23	)	)	PUNCT
dti-2277	91	24	.	.	PUNCT
dti-2277	92	1	within	within	ADP
dti-2277	92	2	the	the	DET
dti-2277	92	3	hiv-1	hiv-1	ADJ
dti-2277	92	4	life	life	NOUN
dti-2277	92	5	cycle	cycle	NOUN
dti-2277	92	6	,	,	PUNCT
dti-2277	92	7	cypa	cypa	PROPN
dti-2277	92	8	plays	play	VERB
dti-2277	92	9	multiple	multiple	ADJ
dti-2277	92	10	roles	role	NOUN
dti-2277	92	11	through	through	ADP
dti-2277	92	12	different	different	ADJ
dti-2277	92	13	interaction	interaction	NOUN
dti-2277	92	14	partners	partner	NOUN
dti-2277	92	15	,	,	PUNCT
dti-2277	92	16	including	include	VERB
dti-2277	92	17	an	an	DET
dti-2277	92	18	early	early	ADJ
dti-2277	92	19	step	step	NOUN
dti-2277	92	20	prior	prior	ADV
dti-2277	92	21	to	to	ADP
dti-2277	92	22	reverse	reverse	VERB
dti-2277	92	23	transcription	transcription	NOUN
dti-2277	92	24	(	(	PUNCT
dti-2277	92	25	braaten	braaten	NOUN
dti-2277	92	26	et	et	PROPN
dti-2277	92	27	al	al	PROPN
dti-2277	92	28	.	.	PROPN
dti-2277	92	29	1996	1996	NUM
dti-2277	92	30	;	;	PUNCT
dti-2277	92	31	mlynar	mlynar	PROPN
dti-2277	92	32	et	et	PROPN
dti-2277	92	33	al	al	PROPN
dti-2277	92	34	.	.	PROPN
dti-2277	92	35	1997	1997	NUM
dti-2277	92	36	;	;	PUNCT
dti-2277	92	37	steinkasserer	steinkasserer	X
dti-2277	92	38	et	et	NOUN
dti-2277	92	39	al.1995	al.1995	PROPN
dti-2277	92	40	)	)	PUNCT
dti-2277	92	41	.	.	PUNCT
dti-2277	93	1	although	although	SCONJ
dti-2277	93	2	cypa	cypa	PROPN
dti-2277	93	3	is	be	AUX
dti-2277	93	4	incorporated	incorporate	VERB
dti-2277	93	5	into	into	ADP
dti-2277	93	6	virions	virion	NOUN
dti-2277	93	7	through	through	ADP
dti-2277	93	8	binding	bind	VERB
dti-2277	93	9	to	to	ADP
dti-2277	93	10	the	the	DET
dti-2277	93	11	ca	ca	NOUN
dti-2277	93	12	domain	domain	NOUN
dti-2277	93	13	of	of	ADP
dti-2277	93	14	the	the	DET
dti-2277	93	15	gag	gag	NOUN
dti-2277	93	16	polyprotein	polyprotein	NOUN
dti-2277	93	17	(	(	PUNCT
dti-2277	93	18	franke	franke	PROPN
dti-2277	93	19	et	et	PROPN
dti-2277	93	20	al	al	PROPN
dti-2277	93	21	.	.	PROPN
dti-2277	93	22	1994	1994	NUM
dti-2277	93	23	;	;	PUNCT
dti-2277	93	24	ott	ott	PROPN
dti-2277	93	25	et	et	PROPN
dti-2277	93	26	al	al	PROPN
dti-2277	93	27	.	.	PROPN
dti-2277	93	28	1995	1995	NUM
dti-2277	93	29	;	;	PUNCT
dti-2277	93	30	thali	thali	PROPN
dti-2277	93	31	et	et	PROPN
dti-2277	93	32	al	al	PROPN
dti-2277	93	33	.	.	PROPN
dti-2277	93	34	1994	1994	NUM
dti-2277	93	35	)	)	PUNCT
dti-2277	93	36	,	,	PUNCT
dti-2277	93	37	this	this	DET
dti-2277	93	38	incorporation	incorporation	NOUN
dti-2277	93	39	is	be	AUX
dti-2277	93	40	not	not	PART
dti-2277	93	41	required	require	VERB
dti-2277	93	42	for	for	ADP
dti-2277	93	43	viral	viral	ADJ
dti-2277	93	44	infection	infection	NOUN
dti-2277	93	45	.	.	PUNCT
dti-2277	94	1	instead	instead	ADV
dti-2277	94	2	,	,	PUNCT
dti-2277	94	3	target	target	NOUN
dti-2277	94	4	cell	cell	NOUN
dti-2277	94	5	expressed	express	VERB
dti-2277	94	6	cypa	cypa	PROPN
dti-2277	94	7	is	be	AUX
dti-2277	94	8	important	important	ADJ
dti-2277	94	9	for	for	ADP
dti-2277	94	10	productive	productive	ADJ
dti-2277	94	11	infection	infection	NOUN
dti-2277	94	12	and	and	CCONJ
dti-2277	94	13	viral	viral	ADJ
dti-2277	94	14	replication	replication	NOUN
dti-2277	94	15	(	(	PUNCT
dti-2277	94	16	hatziioannou	hatziioannou	NOUN
dti-2277	94	17	et	et	PROPN
dti-2277	94	18	al	al	PROPN
dti-2277	94	19	.	.	PROPN
dti-2277	94	20	2005	2005	NUM
dti-2277	94	21	;	;	PUNCT
dti-2277	94	22	sokolskaja	sokolskaja	VERB
dti-2277	94	23	et	et	PROPN
dti-2277	94	24	al	al	PROPN
dti-2277	94	25	.	.	PROPN
dti-2277	94	26	2004	2004	NUM
dti-2277	94	27	)	)	PUNCT
dti-2277	94	28	.	.	PUNCT
dti-2277	95	1	it	it	PRON
dti-2277	95	2	has	have	AUX
dti-2277	95	3	been	be	AUX
dti-2277	95	4	known	know	VERB
dti-2277	95	5	for	for	ADP
dti-2277	95	6	several	several	ADJ
dti-2277	95	7	decades	decade	NOUN
dti-2277	95	8	that	that	SCONJ
dti-2277	95	9	host	host	NOUN
dti-2277	95	10	cells	cell	NOUN
dti-2277	95	11	express	express	VERB
dti-2277	95	12	different	different	ADJ
dti-2277	95	13	restriction	restriction	NOUN
dti-2277	95	14	factors	factor	NOUN
dti-2277	95	15	to	to	PART
dti-2277	95	16	prevent	prevent	VERB
dti-2277	95	17	infection	infection	NOUN
dti-2277	95	18	by	by	ADP
dti-2277	95	19	certain	certain	ADJ
dti-2277	95	20	retroviruses	retrovirus	NOUN
dti-2277	95	21	(	(	PUNCT
dti-2277	95	22	cullen	cullen	VERB
dti-2277	95	23	,	,	PUNCT
dti-2277	95	24	2003	2003	NUM
dti-2277	95	25	)	)	PUNCT
dti-2277	95	26	,	,	PUNCT
dti-2277	95	27	and	and	CCONJ
dti-2277	95	28	several	several	ADJ
dti-2277	95	29	recent	recent	ADJ
dti-2277	95	30	studies	study	NOUN
dti-2277	95	31	have	have	AUX
dti-2277	95	32	suggested	suggest	VERB
dti-2277	95	33	that	that	SCONJ
dti-2277	95	34	cypa	cypa	PROPN
dti-2277	95	35	modulates	modulate	VERB
dti-2277	95	36	sensitivity	sensitivity	NOUN
dti-2277	95	37	to	to	ADP
dti-2277	95	38	such	such	DET
dti-2277	95	39	a	a	DET
dti-2277	95	40	restriction	restriction	NOUN
dti-2277	95	41	factor	factor	NOUN
dti-2277	95	42	early	early	ADV
dti-2277	95	43	in	in	ADP
dti-2277	95	44	the	the	DET
dti-2277	95	45	hiv-1	hiv-1	X
dti-2277	95	46	life	life	NOUN
dti-2277	95	47	cycle	cycle	NOUN
dti-2277	95	48	prior	prior	ADV
dti-2277	95	49	to	to	ADP
dti-2277	95	50	reverse	reverse	VERB
dti-2277	95	51	transcription	transcription	NOUN
dti-2277	95	52	.	.	PUNCT
dti-2277	96	1	trim5α	trim5α	PROPN
dti-2277	96	2	is	be	AUX
dti-2277	96	3	a	a	DET
dti-2277	96	4	host	host	NOUN
dti-2277	96	5	restriction	restriction	NOUN
dti-2277	96	6	factor	factor	NOUN
dti-2277	96	7	originally	originally	ADV
dti-2277	96	8	identifi	identifi	PROPN
dti-2277	96	9	ed	ed	NOUN
dti-2277	96	10	using	use	VERB
dti-2277	96	11	expression	expression	NOUN
dti-2277	96	12	cloning	cloning	NOUN
dti-2277	96	13	that	that	PRON
dti-2277	96	14	recognizes	recognize	VERB
dti-2277	96	15	ca	can	AUX
dti-2277	96	16	limiting	limit	VERB
dti-2277	96	17	retrovirus	retrovirus	NOUN
dti-2277	96	18	proliferation	proliferation	NOUN
dti-2277	96	19	(	(	PUNCT
dti-2277	96	20	stremlau	stremlau	NOUN
dti-2277	96	21	et	et	PROPN
dti-2277	96	22	al	al	PROPN
dti-2277	96	23	.	.	PROPN
dti-2277	96	24	2004	2004	NUM
dti-2277	96	25	)	)	PUNCT
dti-2277	96	26	.	.	PUNCT
dti-2277	97	1	towers	tower	NOUN
dti-2277	97	2	et	et	PROPN
dti-2277	97	3	al	al	PROPN
dti-2277	97	4	.	.	PROPN
dti-2277	97	5	showed	show	VERB
dti-2277	97	6	that	that	SCONJ
dti-2277	97	7	cypa	cypa	PROPN
dti-2277	97	8	regulates	regulate	VERB
dti-2277	97	9	the	the	DET
dti-2277	97	10	activity	activity	NOUN
dti-2277	97	11	of	of	ADP
dti-2277	97	12	a	a	DET
dti-2277	97	13	host	host	NOUN
dti-2277	97	14	restriction	restriction	NOUN
dti-2277	97	15	factor	factor	NOUN
dti-2277	97	16	(	(	PUNCT
dti-2277	97	17	towers	tower	NOUN
dti-2277	97	18	et	et	PROPN
dti-2277	97	19	al	al	PROPN
dti-2277	97	20	.	.	PROPN
dti-2277	97	21	2003	2003	NUM
dti-2277	97	22	)	)	PUNCT
dti-2277	97	23	.	.	PUNCT
dti-2277	98	1	disruption	disruption	NOUN
dti-2277	98	2	of	of	ADP
dti-2277	98	3	cypa	cypa	PROPN
dti-2277	98	4	-	-	PUNCT
dti-2277	98	5	ca	ca	NOUN
dti-2277	98	6	binding	bind	VERB
dti-2277	98	7	by	by	ADP
dti-2277	98	8	introducing	introduce	VERB
dti-2277	98	9	of	of	ADP
dti-2277	98	10	point	point	NOUN
dti-2277	98	11	mutation	mutation	NOUN
dti-2277	98	12	into	into	ADP
dti-2277	98	13	ca	ca	NOUN
dti-2277	98	14	or	or	CCONJ
dti-2277	98	15	treating	treat	VERB
dti-2277	98	16	human	human	ADJ
dti-2277	98	17	cells	cell	NOUN
dti-2277	98	18	with	with	ADP
dti-2277	98	19	csa	csa	PROPN
dti-2277	98	20	decreases	decrease	NOUN
dti-2277	98	21	hiv-1	hiv-1	PART
dti-2277	98	22	infectivity	infectivity	NOUN
dti-2277	98	23	.	.	PUNCT
dti-2277	99	1	conversely	conversely	ADV
dti-2277	99	2	,	,	PUNCT
dti-2277	99	3	the	the	DET
dti-2277	99	4	loss	loss	NOUN
dti-2277	99	5	of	of	ADP
dti-2277	99	6	cypa	cypa	PROPN
dti-2277	99	7	-	-	PUNCT
dti-2277	99	8	ca	ca	NOUN
dti-2277	99	9	binding	bind	VERB
dti-2277	99	10	greatly	greatly	ADV
dti-2277	99	11	enhanced	enhance	VERB
dti-2277	99	12	hiv-1	hiv-1	X
dti-2277	99	13	infectivity	infectivity	NOUN
dti-2277	99	14	in	in	ADP
dti-2277	99	15	simian	simian	ADJ
dti-2277	99	16	cells	cell	NOUN
dti-2277	99	17	(	(	PUNCT
dti-2277	99	18	berthoux	berthoux	VERB
dti-2277	99	19	et	et	PROPN
dti-2277	99	20	al	al	PROPN
dti-2277	99	21	.	.	PROPN
dti-2277	99	22	2005	2005	NUM
dti-2277	99	23	;	;	PUNCT
dti-2277	99	24	kootstra	kootstra	PROPN
dti-2277	99	25	et	et	PROPN
dti-2277	99	26	al	al	PROPN
dti-2277	99	27	.	.	PROPN
dti-2277	99	28	2003	2003	NUM
dti-2277	99	29	;	;	PUNCT
dti-2277	99	30	sayah	sayah	NOUN
dti-2277	99	31	et	et	PROPN
dti-2277	99	32	al	al	PROPN
dti-2277	99	33	.	.	PROPN
dti-2277	99	34	2004	2004	NUM
dti-2277	99	35	)	)	PUNCT
dti-2277	99	36	.	.	PUNCT
dti-2277	100	1	from	from	ADP
dti-2277	100	2	the	the	DET
dti-2277	100	3	results	result	NOUN
dti-2277	100	4	,	,	PUNCT
dti-2277	100	5	the	the	DET
dti-2277	100	6	hypothesis	hypothesis	NOUN
dti-2277	100	7	was	be	AUX
dti-2277	100	8	proposed	propose	VERB
dti-2277	100	9	by	by	ADP
dti-2277	100	10	luban	luban	PROPN
dti-2277	100	11	et	et	PROPN
dti-2277	100	12	al	al	PROPN
dti-2277	100	13	.	.	PUNCT
dti-2277	101	1	that	that	PRON
dti-2277	101	2	ca	can	AUX
dti-2277	101	3	binding	bind	VERB
dti-2277	101	4	by	by	ADP
dti-2277	101	5	cypa	cypa	PROPN
dti-2277	101	6	prevented	prevent	VERB
dti-2277	101	7	normal	normal	ADJ
dti-2277	101	8	antiviral	antiviral	ADJ
dti-2277	101	9	effects	effect	NOUN
dti-2277	101	10	mediated	mediate	VERB
dti-2277	101	11	by	by	ADP
dti-2277	101	12	trim5α	trim5α	PROPN
dti-2277	101	13	during	during	ADP
dti-2277	101	14	hiv-1	hiv-1	X
dti-2277	101	15	infection	infection	NOUN
dti-2277	101	16	of	of	ADP
dti-2277	101	17	human	human	ADJ
dti-2277	101	18	cells	cell	NOUN
dti-2277	101	19	,	,	PUNCT
dti-2277	101	20	but	but	CCONJ
dti-2277	101	21	this	this	DET
dti-2277	101	22	same	same	ADJ
dti-2277	101	23	interaction	interaction	NOUN
dti-2277	101	24	mediated	mediate	VERB
dti-2277	101	25	hiv-1	hiv-1	X
dti-2277	101	26	restriction	restriction	NOUN
dti-2277	101	27	in	in	ADP
dti-2277	101	28	nonhuman	nonhuman	ADJ
dti-2277	101	29	primate	primate	NOUN
dti-2277	101	30	cells	cell	NOUN
dti-2277	101	31	(	(	PUNCT
dti-2277	101	32	sokolskaja	sokolskaja	VERB
dti-2277	101	33	et	et	PROPN
dti-2277	101	34	al	al	PROPN
dti-2277	101	35	.	.	PROPN
dti-2277	101	36	2006	2006	NUM
dti-2277	101	37	;	;	PUNCT
dti-2277	101	38	luban	luban	VERB
dti-2277	101	39	,	,	PUNCT
dti-2277	101	40	in	in	ADP
dti-2277	101	41	press	press	NOUN
dti-2277	101	42	)	)	PUNCT
dti-2277	101	43	.	.	PUNCT
dti-2277	102	1	both	both	PRON
dti-2277	102	2	the	the	DET
dti-2277	102	3	mechanism	mechanism	NOUN
dti-2277	102	4	of	of	ADP
dti-2277	102	5	trim5α	trim5α	PROPN
dti-2277	102	6	restriction	restriction	NOUN
dti-2277	102	7	of	of	ADP
dti-2277	102	8	hiv-1	hiv-1	X
dti-2277	102	9	and	and	CCONJ
dti-2277	102	10	the	the	DET
dti-2277	102	11	modulation	modulation	NOUN
dti-2277	102	12	of	of	ADP
dti-2277	102	13	ca	ca	NOUN
dti-2277	102	14	recognition	recognition	NOUN
dti-2277	102	15	by	by	ADP
dti-2277	102	16	cypa	cypa	NOUN
dti-2277	102	17	remain	remain	VERB
dti-2277	102	18	unclear	unclear	ADJ
dti-2277	102	19	,	,	PUNCT
dti-2277	102	20	and	and	CCONJ
dti-2277	102	21	further	further	ADJ
dti-2277	102	22	studies	study	NOUN
dti-2277	102	23	are	be	AUX
dti-2277	102	24	clearly	clearly	ADV
dti-2277	102	25	needed	need	VERB
dti-2277	102	26	to	to	PART
dti-2277	102	27	resolve	resolve	VERB
dti-2277	102	28	these	these	DET
dti-2277	102	29	important	important	ADJ
dti-2277	102	30	issues	issue	NOUN
dti-2277	102	31	in	in	ADP
dti-2277	102	32	the	the	DET
dti-2277	102	33	hiv-1	hiv-1	X
dti-2277	102	34	life	life	NOUN
dti-2277	102	35	cycle	cycle	NOUN
dti-2277	102	36	and	and	CCONJ
dti-2277	102	37	the	the	DET
dti-2277	102	38	host	host	NOUN
dti-2277	102	39	response	response	NOUN
dti-2277	102	40	to	to	ADP
dti-2277	102	41	hiv-1	hiv-1	ADJ
dti-2277	102	42	infection	infection	NOUN
dti-2277	102	43	.	.	PUNCT
dti-2277	103	1	cypa	cypa	PROPN
dti-2277	103	2	may	may	AUX
dti-2277	103	3	be	be	AUX
dti-2277	103	4	important	important	ADJ
dti-2277	103	5	for	for	ADP
dti-2277	103	6	other	other	ADJ
dti-2277	103	7	aspects	aspect	NOUN
dti-2277	103	8	of	of	ADP
dti-2277	103	9	hiv-1	hiv-1	ADJ
dti-2277	103	10	infection	infection	NOUN
dti-2277	103	11	.	.	PUNCT
dti-2277	104	1	cypa	cypa	PROPN
dti-2277	104	2	interacts	interact	VERB
dti-2277	104	3	with	with	ADP
dti-2277	104	4	cd147	cd147	PROPN
dti-2277	104	5	(	(	PUNCT
dti-2277	104	6	pushkarsky	pushkarsky	ADV
dti-2277	104	7	et	et	PROPN
dti-2277	104	8	al	al	PROPN
dti-2277	104	9	.	.	PROPN
dti-2277	104	10	2001	2001	NUM
dti-2277	104	11	)	)	PUNCT
dti-2277	104	12	,	,	PUNCT
dti-2277	104	13	heparans	heparan	VERB
dti-2277	104	14	(	(	PUNCT
dti-2277	104	15	saphire	saphire	NOUN
dti-2277	104	16	et	et	PROPN
dti-2277	104	17	al	al	PROPN
dti-2277	104	18	.	.	PROPN
dti-2277	104	19	1999	1999	NUM
dti-2277	104	20	)	)	PUNCT
dti-2277	104	21	,	,	PUNCT
dti-2277	104	22	vpr	vpr	NOUN
dti-2277	104	23	(	(	PUNCT
dti-2277	104	24	zander	zander	NOUN
dti-2277	104	25	et	et	PROPN
dti-2277	104	26	al	al	PROPN
dti-2277	104	27	.	.	PROPN
dti-2277	104	28	2003	2003	NUM
dti-2277	104	29	)	)	PUNCT
dti-2277	104	30	,	,	PUNCT
dti-2277	104	31	and	and	CCONJ
dti-2277	104	32	envelope	envelope	VERB
dti-2277	104	33	glycoprotein	glycoprotein	NOUN
dti-2277	104	34	gp120	gp120	PROPN
dti-2277	104	35	(	(	PUNCT
dti-2277	104	36	endrich	endrich	ADV
dti-2277	104	37	and	and	CCONJ
dti-2277	104	38	gehring	gehring	NOUN
dti-2277	104	39	,	,	PUNCT
dti-2277	104	40	1998	1998	NUM
dti-2277	104	41	)	)	PUNCT
dti-2277	104	42	,	,	PUNCT
dti-2277	104	43	although	although	SCONJ
dti-2277	104	44	their	their	PRON
dti-2277	104	45	relevances	relevance	NOUN
dti-2277	104	46	of	of	ADP
dti-2277	104	47	the	the	DET
dti-2277	104	48	interactions	interaction	NOUN
dti-2277	104	49	should	should	AUX
dti-2277	104	50	be	be	AUX
dti-2277	104	51	further	further	ADJ
dti-2277	104	52	verifi	verifi	PROPN
dti-2277	104	53	ed	ed	PROPN
dti-2277	104	54	.	.	PUNCT
dti-2277	105	1	cypb	cypb	PROPN
dti-2277	105	2	and	and	CCONJ
dti-2277	105	3	hcv	hcv	VERB
dti-2277	105	4	current	current	ADJ
dti-2277	105	5	therapy	therapy	NOUN
dti-2277	105	6	against	against	ADP
dti-2277	105	7	hcv	hcv	PROPN
dti-2277	105	8	hcv	hcv	PROPN
dti-2277	105	9	is	be	AUX
dti-2277	105	10	a	a	DET
dti-2277	105	11	major	major	ADJ
dti-2277	105	12	causative	causative	ADJ
dti-2277	105	13	agent	agent	NOUN
dti-2277	105	14	of	of	ADP
dti-2277	105	15	chronic	chronic	ADJ
dti-2277	105	16	liver	liver	NOUN
dti-2277	105	17	diseases	disease	NOUN
dti-2277	105	18	such	such	ADJ
dti-2277	105	19	as	as	ADP
dti-2277	105	20	chronic	chronic	ADJ
dti-2277	105	21	hepatitis	hepatitis	NOUN
dti-2277	105	22	,	,	PUNCT
dti-2277	105	23	liver	liver	NOUN
dti-2277	105	24	cirrhosis	cirrhosis	NOUN
dti-2277	105	25	,	,	PUNCT
dti-2277	105	26	and	and	CCONJ
dti-2277	105	27	hepatocellular	hepatocellular	ADJ
dti-2277	105	28	carcinoma	carcinoma	NOUN
dti-2277	105	29	(	(	PUNCT
dti-2277	105	30	liang	liang	PROPN
dti-2277	105	31	et	et	PROPN
dti-2277	105	32	al	al	PROPN
dti-2277	105	33	.	.	PROPN
dti-2277	105	34	1993	1993	NUM
dti-2277	105	35	)	)	PUNCT
dti-2277	105	36	.	.	PUNCT
dti-2277	106	1	hcv	hcv	NOUN
dti-2277	106	2	infection	infection	NOUN
dti-2277	106	3	is	be	AUX
dti-2277	106	4	a	a	DET
dti-2277	106	5	serious	serious	ADJ
dti-2277	106	6	health	health	NOUN
dti-2277	106	7	problem	problem	NOUN
dti-2277	106	8	affecting	affect	VERB
dti-2277	106	9	approximately	approximately	ADV
dti-2277	106	10	170	170	NUM
dti-2277	106	11	million	million	NUM
dti-2277	106	12	individuals	individual	NOUN
dti-2277	106	13	worldwide	worldwide	ADV
dti-2277	106	14	(	(	PUNCT
dti-2277	106	15	poynard	poynard	NOUN
dti-2277	106	16	et	et	PROPN
dti-2277	106	17	al	al	PROPN
dti-2277	106	18	.	.	PROPN
dti-2277	106	19	2003	2003	NUM
dti-2277	106	20	)	)	PUNCT
dti-2277	106	21	.	.	PUNCT
dti-2277	107	1	the	the	DET
dti-2277	107	2	current	current	ADJ
dti-2277	107	3	standard	standard	ADJ
dti-2277	107	4	therapy	therapy	NOUN
dti-2277	107	5	for	for	ADP
dti-2277	107	6	hcv	hcv	PROPN
dti-2277	107	7	is	be	AUX
dti-2277	107	8	restricted	restrict	VERB
dti-2277	107	9	to	to	ADP
dti-2277	107	10	interferon	interferon	NOUN
dti-2277	107	11	(	(	PUNCT
dti-2277	107	12	ifn	ifn	PROPN
dti-2277	107	13	)	)	PUNCT
dti-2277	107	14	or	or	CCONJ
dti-2277	107	15	pegylated	pegylate	VERB
dti-2277	107	16	-	-	PUNCT
dti-2277	107	17	ifn	ifn	NOUN
dti-2277	107	18	either	either	CCONJ
dti-2277	107	19	alone	alone	ADJ
dti-2277	107	20	or	or	CCONJ
dti-2277	107	21	in	in	ADP
dti-2277	107	22	combination	combination	NOUN
dti-2277	107	23	with	with	ADP
dti-2277	107	24	ribavirin	ribavirin	NOUN
dti-2277	107	25	.	.	PUNCT
dti-2277	108	1	because	because	SCONJ
dti-2277	108	2	treatment	treatment	NOUN
dti-2277	108	3	with	with	ADP
dti-2277	108	4	these	these	DET
dti-2277	108	5	agents	agent	NOUN
dti-2277	108	6	,	,	PUNCT
dti-2277	108	7	however	however	ADV
dti-2277	108	8	,	,	PUNCT
dti-2277	108	9	fails	fail	VERB
dti-2277	108	10	to	to	PART
dti-2277	108	11	produce	produce	VERB
dti-2277	108	12	sustained	sustained	ADJ
dti-2277	108	13	virus	virus	NOUN
dti-2277	108	14	elimination	elimination	NOUN
dti-2277	108	15	in	in	ADP
dti-2277	108	16	about	about	ADV
dti-2277	108	17	one	one	NUM
dti-2277	108	18	half	half	NOUN
dti-2277	108	19	of	of	ADP
dti-2277	108	20	the	the	DET
dti-2277	108	21	patients	patient	NOUN
dti-2277	108	22	(	(	PUNCT
dti-2277	108	23	di	di	X
dti-2277	108	24	bisceglie	bisceglie	PROPN
dti-2277	108	25	et	et	PROPN
dti-2277	108	26	al	al	PROPN
dti-2277	108	27	.	.	PROPN
dti-2277	108	28	2002	2002	NUM
dti-2277	108	29	)	)	PUNCT
dti-2277	108	30	,	,	PUNCT
dti-2277	108	31	alternative	alternative	ADJ
dti-2277	108	32	and	and	CCONJ
dti-2277	108	33	effective	effective	ADJ
dti-2277	108	34	strategies	strategy	NOUN
dti-2277	108	35	to	to	PART
dti-2277	108	36	combat	combat	VERB
dti-2277	108	37	against	against	ADP
dti-2277	108	38	hcv	hcv	NOUN
dti-2277	108	39	are	be	AUX
dti-2277	108	40	greatly	greatly	ADV
dti-2277	108	41	needed	need	VERB
dti-2277	108	42	.	.	PUNCT
dti-2277	109	1	hcv	hcv	VERB
dti-2277	109	2	encodes	encode	NOUN
dti-2277	109	3	a	a	DET
dti-2277	109	4	single	single	ADJ
dti-2277	109	5	polypeptide	polypeptide	NOUN
dti-2277	109	6	that	that	PRON
dti-2277	109	7	is	be	AUX
dti-2277	109	8	cleaved	cleave	VERB
dti-2277	109	9	by	by	ADP
dti-2277	109	10	host	host	NOUN
dti-2277	109	11	and	and	CCONJ
dti-2277	109	12	hcv	hcv	NOUN
dti-2277	109	13	-	-	PUNCT
dti-2277	109	14	encoded	encode	VERB
dti-2277	109	15	protease	protease	NOUN
dti-2277	109	16	including	include	VERB
dti-2277	109	17	ns3	ns3	NOUN
dti-2277	109	18	to	to	PART
dti-2277	109	19	generate	generate	VERB
dti-2277	109	20	a	a	DET
dti-2277	109	21	set	set	NOUN
dti-2277	109	22	of	of	ADP
dti-2277	109	23	functional	functional	ADJ
dti-2277	109	24	proteins	protein	NOUN
dti-2277	109	25	.	.	PUNCT
dti-2277	110	1	its	its	PRON
dti-2277	110	2	genome	genome	NOUN
dti-2277	110	3	is	be	AUX
dti-2277	110	4	replicated	replicate	VERB
dti-2277	110	5	by	by	ADP
dti-2277	110	6	the	the	DET
dti-2277	110	7	hcv	hcv	PROPN
dti-2277	110	8	-	-	PUNCT
dti-2277	110	9	encoded	encode	VERB
dti-2277	110	10	rna	rna	NOUN
dti-2277	110	11	-	-	PUNCT
dti-2277	110	12	dependent	dependent	ADJ
dti-2277	110	13	rna	rna	NOUN
dti-2277	110	14	polymerase	polymerase	NOUN
dti-2277	110	15	(	(	PUNCT
dti-2277	110	16	rdrp	rdrp	NOUN
dti-2277	110	17	)	)	PUNCT
dti-2277	110	18	ns5b	ns5b	PROPN
dti-2277	110	19	.	.	PUNCT
dti-2277	111	1	both	both	PRON
dti-2277	111	2	of	of	ADP
dti-2277	111	3	these	these	DET
dti-2277	111	4	proteins	protein	NOUN
dti-2277	111	5	,	,	PUNCT
dti-2277	111	6	ns3	ns3	NOUN
dti-2277	111	7	and	and	CCONJ
dti-2277	111	8	ns5b	ns5b	PROPN
dti-2277	111	9	,	,	PUNCT
dti-2277	111	10	are	be	AUX
dti-2277	111	11	essential	essential	ADJ
dti-2277	111	12	for	for	ADP
dti-2277	111	13	hcv	hcv	NOUN
dti-2277	111	14	genome	genome	NOUN
dti-2277	111	15	replication	replication	NOUN
dti-2277	111	16	and	and	CCONJ
dti-2277	111	17	are	be	AUX
dti-2277	111	18	possible	possible	ADJ
dti-2277	111	19	targets	target	NOUN
dti-2277	111	20	for	for	ADP
dti-2277	111	21	the	the	DET
dti-2277	111	22	development	development	NOUN
dti-2277	111	23	of	of	ADP
dti-2277	111	24	anti	anti	ADJ
dti-2277	111	25	-	-	ADJ
dti-2277	111	26	hcv	hcv	ADJ
dti-2277	111	27	therapeutics	therapeutic	NOUN
dti-2277	111	28	(	(	PUNCT
dti-2277	111	29	di	di	X
dti-2277	111	30	bisceglie	bisceglie	PROPN
dti-2277	111	31	et	et	PROPN
dti-2277	111	32	al	al	PROPN
dti-2277	111	33	.	.	PROPN
dti-2277	111	34	2002	2002	NUM
dti-2277	111	35	)	)	PUNCT
dti-2277	111	36	.	.	PUNCT
dti-2277	112	1	small	small	ADJ
dti-2277	112	2	molecule	molecule	NOUN
dti-2277	112	3	compounds	compound	NOUN
dti-2277	112	4	targeting	target	VERB
dti-2277	112	5	ns3	ns3	NOUN
dti-2277	112	6	and	and	CCONJ
dti-2277	112	7	ns5b	ns5b	PROPN
dti-2277	112	8	have	have	AUX
dti-2277	112	9	been	be	AUX
dti-2277	112	10	developed	develop	VERB
dti-2277	112	11	,	,	PUNCT
dti-2277	112	12	and	and	CCONJ
dti-2277	112	13	their	their	PRON
dti-2277	112	14	effi	effi	PROPN
dti-2277	112	15	cacy	cacy	NOUN
dti-2277	112	16	has	have	AUX
dti-2277	112	17	been	be	AUX
dti-2277	112	18	examined	examine	VERB
dti-2277	112	19	in	in	ADP
dti-2277	112	20	clinical	clinical	ADJ
dti-2277	112	21	trials	trial	NOUN
dti-2277	112	22	(	(	PUNCT
dti-2277	112	23	di	di	X
dti-2277	112	24	bisceglie	bisceglie	PROPN
dti-2277	112	25	et	et	PROPN
dti-2277	112	26	al	al	PROPN
dti-2277	112	27	.	.	PROPN
dti-2277	112	28	2002	2002	NUM
dti-2277	112	29	)	)	PUNCT
dti-2277	112	30	.	.	PUNCT
dti-2277	113	1	in	in	ADP
dti-2277	113	2	addition	addition	NOUN
dti-2277	113	3	to	to	ADP
dti-2277	113	4	these	these	DET
dti-2277	113	5	viral	viral	ADJ
dti-2277	113	6	enzymes	enzyme	NOUN
dti-2277	113	7	,	,	PUNCT
dti-2277	113	8	host	host	NOUN
dti-2277	113	9	cell	cell	NOUN
dti-2277	113	10	factors	factor	NOUN
dti-2277	113	11	are	be	AUX
dti-2277	113	12	required	require	VERB
dti-2277	113	13	for	for	ADP
dti-2277	113	14	viral	viral	ADJ
dti-2277	113	15	replication	replication	NOUN
dti-2277	113	16	,	,	PUNCT
dti-2277	113	17	and	and	CCONJ
dti-2277	113	18	these	these	PRON
dti-2277	113	19	may	may	AUX
dti-2277	113	20	provide	provide	VERB
dti-2277	113	21	other	other	ADJ
dti-2277	113	22	options	option	NOUN
dti-2277	113	23	for	for	ADP
dti-2277	113	24	the	the	DET
dti-2277	113	25	development	development	NOUN
dti-2277	113	26	of	of	ADP
dti-2277	113	27	novel	novel	ADJ
dti-2277	113	28	anti	anti	ADJ
dti-2277	113	29	-	-	ADJ
dti-2277	113	30	viral	viral	ADJ
dti-2277	113	31	agents	agent	NOUN
dti-2277	113	32	.	.	PUNCT
dti-2277	114	1	disrupting	disrupt	VERB
dti-2277	114	2	the	the	DET
dti-2277	114	3	function	function	NOUN
dti-2277	114	4	of	of	ADP
dti-2277	114	5	drug	drug	NOUN
dti-2277	114	6	target	target	NOUN
dti-2277	114	7	insights	insight	NOUN
dti-2277	114	8	2007	2007	NUM
dti-2277	114	9	:	:	PUNCT
dti-2277	114	10	2	2	NUM
dti-2277	114	11	13	13	NUM
dti-2277	114	12	cyclophilin	cyclophilin	NOUN
dti-2277	114	13	and	and	CCONJ
dti-2277	114	14	viruses	viruse	VERB
dti-2277	114	15	host	host	NOUN
dti-2277	114	16	cell	cell	NOUN
dti-2277	114	17	derived	derive	VERB
dti-2277	114	18	factors	factor	NOUN
dti-2277	114	19	is	be	AUX
dti-2277	114	20	particularly	particularly	ADV
dti-2277	114	21	appealing	appealing	ADJ
dti-2277	114	22	as	as	SCONJ
dti-2277	114	23	the	the	DET
dti-2277	114	24	mutation	mutation	NOUN
dti-2277	114	25	rate	rate	NOUN
dti-2277	114	26	of	of	ADP
dti-2277	114	27	host	host	NOUN
dti-2277	114	28	proteins	protein	NOUN
dti-2277	114	29	is	be	AUX
dti-2277	114	30	much	much	ADV
dti-2277	114	31	less	less	ADJ
dti-2277	114	32	than	than	ADP
dti-2277	114	33	that	that	PRON
dti-2277	114	34	of	of	ADP
dti-2277	114	35	viral	viral	ADJ
dti-2277	114	36	encoded	encode	VERB
dti-2277	114	37	proteins	protein	NOUN
dti-2277	114	38	and	and	CCONJ
dti-2277	114	39	should	should	AUX
dti-2277	114	40	less	less	ADV
dti-2277	114	41	give	give	VERB
dti-2277	114	42	rise	rise	NOUN
dti-2277	114	43	to	to	ADP
dti-2277	114	44	drug	drug	NOUN
dti-2277	114	45	-	-	PUNCT
dti-2277	114	46	resistant	resistant	ADJ
dti-2277	114	47	viruses	virus	NOUN
dti-2277	114	48	.	.	PUNCT
dti-2277	115	1	however	however	ADV
dti-2277	115	2	,	,	PUNCT
dti-2277	115	3	while	while	SCONJ
dti-2277	115	4	some	some	DET
dti-2277	115	5	host	host	NOUN
dti-2277	115	6	factors	factor	NOUN
dti-2277	115	7	required	require	VERB
dti-2277	115	8	for	for	ADP
dti-2277	115	9	viral	viral	ADJ
dti-2277	115	10	genome	genome	NOUN
dti-2277	115	11	replication	replication	NOUN
dti-2277	115	12	have	have	AUX
dti-2277	115	13	been	be	AUX
dti-2277	115	14	identifi	identifi	PROPN
dti-2277	115	15	ed	ed	NOUN
dti-2277	115	16	,	,	PUNCT
dti-2277	115	17	other	other	ADJ
dti-2277	115	18	host	host	NOUN
dti-2277	115	19	proteins	protein	NOUN
dti-2277	115	20	need	need	VERB
dti-2277	115	21	to	to	PART
dti-2277	115	22	be	be	AUX
dti-2277	115	23	identifi	identifi	PROPN
dti-2277	115	24	ed	ed	NOUN
dti-2277	115	25	to	to	PART
dti-2277	115	26	develop	develop	VERB
dti-2277	115	27	optimal	optimal	ADJ
dti-2277	115	28	anti	anti	ADJ
dti-2277	115	29	-	-	ADJ
dti-2277	115	30	viral	viral	ADJ
dti-2277	115	31	therapies	therapy	NOUN
dti-2277	115	32	with	with	ADP
dti-2277	115	33	few	few	ADJ
dti-2277	115	34	side	side	NOUN
dti-2277	115	35	effects	effect	NOUN
dti-2277	115	36	.	.	PUNCT
dti-2277	116	1	at	at	ADP
dti-2277	116	2	this	this	DET
dti-2277	116	3	time	time	NOUN
dti-2277	116	4	,	,	PUNCT
dti-2277	116	5	only	only	ADV
dti-2277	116	6	a	a	DET
dti-2277	116	7	limited	limited	ADJ
dti-2277	116	8	number	number	NOUN
dti-2277	116	9	of	of	ADP
dti-2277	116	10	host	host	NOUN
dti-2277	116	11	proteins	protein	NOUN
dti-2277	116	12	have	have	AUX
dti-2277	116	13	been	be	AUX
dti-2277	116	14	found	find	VERB
dti-2277	116	15	to	to	PART
dti-2277	116	16	be	be	AUX
dti-2277	116	17	involved	involve	VERB
dti-2277	116	18	in	in	ADP
dti-2277	116	19	hcv	hcv	NOUN
dti-2277	116	20	genome	genome	NOUN
dti-2277	116	21	replication	replication	NOUN
dti-2277	116	22	with	with	ADP
dti-2277	116	23	biological	biological	ADJ
dti-2277	116	24	relevance	relevance	NOUN
dti-2277	116	25	.	.	PUNCT
dti-2277	117	1	hvap-33	hvap-33	PROPN
dti-2277	117	2	is	be	AUX
dti-2277	117	3	one	one	NUM
dti-2277	117	4	of	of	ADP
dti-2277	117	5	snare	snare	NOUN
dti-2277	117	6	family	family	NOUN
dti-2277	117	7	proteins	protein	NOUN
dti-2277	117	8	that	that	PRON
dti-2277	117	9	regulate	regulate	VERB
dti-2277	117	10	vesicle	vesicle	NOUN
dti-2277	117	11	biogenesis	biogenesis	NOUN
dti-2277	117	12	,	,	PUNCT
dti-2277	117	13	protein	protein	NOUN
dti-2277	117	14	sorting	sorting	NOUN
dti-2277	117	15	,	,	PUNCT
dti-2277	117	16	and	and	CCONJ
dti-2277	117	17	membrane	membrane	NOUN
dti-2277	117	18	fusion	fusion	NOUN
dti-2277	117	19	.	.	PUNCT
dti-2277	118	1	hvap-33	hvap-33	PROPN
dti-2277	118	2	binds	bind	VERB
dti-2277	118	3	hcv	hcv	X
dti-2277	118	4	ns5a	ns5a	PROPN
dti-2277	118	5	and	and	CCONJ
dti-2277	118	6	ns5b	ns5b	PROPN
dti-2277	118	7	,	,	PUNCT
dti-2277	118	8	and	and	CCONJ
dti-2277	118	9	this	this	DET
dti-2277	118	10	interaction	interaction	NOUN
dti-2277	118	11	regulates	regulate	VERB
dti-2277	118	12	the	the	DET
dti-2277	118	13	presence	presence	NOUN
dti-2277	118	14	of	of	ADP
dti-2277	118	15	hcv	hcv	ADJ
dti-2277	118	16	proteins	protein	NOUN
dti-2277	118	17	in	in	ADP
dti-2277	118	18	the	the	DET
dti-2277	118	19	subcellular	subcellular	ADJ
dti-2277	118	20	compartment	compartment	NOUN
dti-2277	118	21	performing	perform	VERB
dti-2277	118	22	viral	viral	ADJ
dti-2277	118	23	genome	genome	NOUN
dti-2277	118	24	replication	replication	NOUN
dti-2277	118	25	(	(	PUNCT
dti-2277	118	26	evans	evans	PROPN
dti-2277	118	27	et	et	PROPN
dti-2277	118	28	al	al	PROPN
dti-2277	118	29	.	.	PROPN
dti-2277	118	30	2004	2004	NUM
dti-2277	118	31	;	;	PUNCT
dti-2277	118	32	gao	gao	PROPN
dti-2277	118	33	et	et	PROPN
dti-2277	118	34	al	al	PROPN
dti-2277	118	35	.	.	PROPN
dti-2277	118	36	2004	2004	NUM
dti-2277	118	37	;	;	PUNCT
dti-2277	118	38	tu	tu	PROPN
dti-2277	118	39	et	et	PROPN
dti-2277	118	40	al	al	PROPN
dti-2277	118	41	.	.	PROPN
dti-2277	118	42	1999	1999	NUM
dti-2277	118	43	)	)	PUNCT
dti-2277	118	44	.	.	PUNCT
dti-2277	119	1	fbl2	fbl2	PROPN
dti-2277	119	2	is	be	AUX
dti-2277	119	3	a	a	DET
dti-2277	119	4	member	member	NOUN
dti-2277	119	5	of	of	ADP
dti-2277	119	6	the	the	DET
dti-2277	119	7	f	f	PROPN
dti-2277	119	8	-	-	PUNCT
dti-2277	119	9	box	box	NOUN
dti-2277	119	10	protein	protein	NOUN
dti-2277	119	11	family	family	NOUN
dti-2277	119	12	,	,	PUNCT
dti-2277	119	13	involved	involve	VERB
dti-2277	119	14	in	in	ADP
dti-2277	119	15	the	the	DET
dti-2277	119	16	ubiquitination	ubiquitination	NOUN
dti-2277	119	17	pathway	pathway	NOUN
dti-2277	119	18	.	.	PUNCT
dti-2277	120	1	fbl2	fbl2	NOUN
dti-2277	120	2	is	be	AUX
dti-2277	120	3	geranylgeranylated	geranylgeranylate	VERB
dti-2277	120	4	in	in	ADP
dti-2277	120	5	cells	cell	NOUN
dti-2277	120	6	(	(	PUNCT
dti-2277	120	7	wang	wang	PROPN
dti-2277	120	8	et	et	PROPN
dti-2277	120	9	al	al	PROPN
dti-2277	120	10	.	.	PROPN
dti-2277	120	11	2005	2005	NUM
dti-2277	120	12	)	)	PUNCT
dti-2277	120	13	,	,	PUNCT
dti-2277	120	14	and	and	CCONJ
dti-2277	120	15	associates	associate	NOUN
dti-2277	120	16	with	with	ADP
dti-2277	120	17	ns5a	ns5a	NOUN
dti-2277	120	18	in	in	ADP
dti-2277	120	19	a	a	DET
dti-2277	120	20	geranylgeranylation	geranylgeranylation	NOUN
dti-2277	120	21	-	-	PUNCT
dti-2277	120	22	dependent	dependent	ADJ
dti-2277	120	23	manner	manner	NOUN
dti-2277	120	24	to	to	PART
dti-2277	120	25	regulate	regulate	VERB
dti-2277	120	26	hcv	hcv	NOUN
dti-2277	120	27	genome	genome	NOUN
dti-2277	120	28	replication	replication	NOUN
dti-2277	120	29	.	.	PUNCT
dti-2277	121	1	however	however	ADV
dti-2277	121	2	,	,	PUNCT
dti-2277	121	3	the	the	DET
dti-2277	121	4	mechanism	mechanism	NOUN
dti-2277	121	5	of	of	ADP
dti-2277	121	6	action	action	NOUN
dti-2277	121	7	of	of	ADP
dti-2277	121	8	fbl2	fbl2	NOUN
dti-2277	121	9	in	in	ADP
dti-2277	121	10	hcv	hcv	NOUN
dti-2277	121	11	genome	genome	NOUN
dti-2277	121	12	replication	replication	NOUN
dti-2277	121	13	is	be	AUX
dti-2277	121	14	not	not	PART
dti-2277	121	15	known	know	VERB
dti-2277	121	16	.	.	PUNCT
dti-2277	122	1	additionally	additionally	ADV
dti-2277	122	2	,	,	PUNCT
dti-2277	122	3	we	we	PRON
dti-2277	122	4	recently	recently	ADV
dti-2277	122	5	found	find	VERB
dti-2277	122	6	that	that	SCONJ
dti-2277	122	7	cypb	cypb	NOUN
dti-2277	122	8	is	be	AUX
dti-2277	122	9	a	a	DET
dti-2277	122	10	cofactor	cofactor	NOUN
dti-2277	122	11	for	for	ADP
dti-2277	122	12	hcv	hcv	NOUN
dti-2277	122	13	replication	replication	NOUN
dti-2277	122	14	in	in	ADP
dti-2277	122	15	host	host	NOUN
dti-2277	122	16	cells	cell	NOUN
dti-2277	122	17	,	,	PUNCT
dti-2277	122	18	and	and	CCONJ
dti-2277	122	19	this	this	PRON
dti-2277	122	20	may	may	AUX
dti-2277	122	21	represent	represent	VERB
dti-2277	122	22	a	a	DET
dti-2277	122	23	new	new	ADJ
dti-2277	122	24	target	target	NOUN
dti-2277	122	25	for	for	ADP
dti-2277	122	26	anti	anti	ADJ
dti-2277	122	27	-	-	ADJ
dti-2277	122	28	hcv	hcv	ADJ
dti-2277	122	29	therapeutics	therapeutic	NOUN
dti-2277	122	30	(	(	PUNCT
dti-2277	122	31	watashi	watashi	NOUN
dti-2277	122	32	et	et	PROPN
dti-2277	122	33	al	al	PROPN
dti-2277	122	34	.	.	PROPN
dti-2277	122	35	2005	2005	NUM
dti-2277	122	36	)	)	PUNCT
dti-2277	122	37	.	.	PUNCT
dti-2277	123	1	we	we	PRON
dti-2277	123	2	will	will	AUX
dti-2277	123	3	fi	fi	VERB
dti-2277	123	4	rst	rst	AUX
dti-2277	123	5	discuss	discuss	VERB
dti-2277	123	6	the	the	DET
dti-2277	123	7	role	role	NOUN
dti-2277	123	8	of	of	ADP
dti-2277	123	9	cypb	cypb	NOUN
dti-2277	123	10	in	in	ADP
dti-2277	123	11	hcv	hcv	NOUN
dti-2277	123	12	genome	genome	NOUN
dti-2277	123	13	replication	replication	NOUN
dti-2277	123	14	followed	follow	VERB
dti-2277	123	15	by	by	ADP
dti-2277	123	16	the	the	DET
dti-2277	123	17	therapeutic	therapeutic	ADJ
dti-2277	123	18	implications	implication	NOUN
dti-2277	123	19	of	of	ADP
dti-2277	123	20	this	this	DET
dti-2277	123	21	discovery	discovery	NOUN
dti-2277	123	22	in	in	ADP
dti-2277	123	23	hcv	hcv	PROPN
dti-2277	123	24	treatment	treatment	NOUN
dti-2277	123	25	.	.	PUNCT
dti-2277	124	1	anti	anti	ADJ
dti-2277	124	2	-	-	ADJ
dti-2277	124	3	hcv	hcv	ADJ
dti-2277	124	4	activity	activity	NOUN
dti-2277	124	5	of	of	ADP
dti-2277	124	6	cyclosporin	cyclosporin	NOUN
dti-2277	124	7	we	we	PRON
dti-2277	124	8	identifi	identifi	VERB
dti-2277	124	9	ed	ed	PROPN
dti-2277	124	10	csa	csa	PROPN
dti-2277	124	11	as	as	ADP
dti-2277	124	12	an	an	DET
dti-2277	124	13	anti	anti	ADJ
dti-2277	124	14	-	-	ADJ
dti-2277	124	15	hcv	hcv	ADJ
dti-2277	124	16	agent	agent	NOUN
dti-2277	124	17	using	use	VERB
dti-2277	124	18	a	a	DET
dti-2277	124	19	hcv	hcv	ADJ
dti-2277	124	20	replicon	replicon	NOUN
dti-2277	124	21	system	system	NOUN
dti-2277	124	22	,	,	PUNCT
dti-2277	124	23	a	a	DET
dti-2277	124	24	cell	cell	NOUN
dti-2277	124	25	culture	culture	NOUN
dti-2277	124	26	system	system	NOUN
dti-2277	124	27	supporting	support	VERB
dti-2277	124	28	hcv	hcv	NOUN
dti-2277	124	29	genome	genome	NOUN
dti-2277	124	30	replication	replication	NOUN
dti-2277	124	31	(	(	PUNCT
dti-2277	124	32	lohmann	lohmann	PROPN
dti-2277	124	33	et	et	PROPN
dti-2277	124	34	al	al	PROPN
dti-2277	124	35	.	.	PROPN
dti-2277	124	36	1999	1999	NUM
dti-2277	124	37	)	)	PUNCT
dti-2277	124	38	,	,	PUNCT
dti-2277	124	39	and	and	CCONJ
dti-2277	124	40	csa	csa	PROPN
dti-2277	124	41	inhibits	inhibit	VERB
dti-2277	124	42	hcv	hcv	NOUN
dti-2277	124	43	genome	genome	NOUN
dti-2277	124	44	replication	replication	NOUN
dti-2277	124	45	as	as	ADV
dti-2277	124	46	potently	potently	ADV
dti-2277	124	47	as	as	ADP
dti-2277	124	48	ifnα	ifnα	NOUN
dti-2277	124	49	(	(	PUNCT
dti-2277	124	50	watashi	watashi	NOUN
dti-2277	124	51	et	et	PROPN
dti-2277	124	52	al	al	PROPN
dti-2277	124	53	.	.	PROPN
dti-2277	124	54	2003	2003	NUM
dti-2277	124	55	)	)	PUNCT
dti-2277	124	56	.	.	PUNCT
dti-2277	125	1	since	since	SCONJ
dti-2277	125	2	that	that	DET
dti-2277	125	3	time	time	NOUN
dti-2277	125	4	,	,	PUNCT
dti-2277	125	5	several	several	ADJ
dti-2277	125	6	groups	group	NOUN
dti-2277	125	7	have	have	AUX
dti-2277	125	8	made	make	VERB
dti-2277	125	9	similar	similar	ADJ
dti-2277	125	10	observations	observation	NOUN
dti-2277	125	11	(	(	PUNCT
dti-2277	125	12	firpi	firpi	NOUN
dti-2277	125	13	et	et	PROPN
dti-2277	125	14	al	al	PROPN
dti-2277	125	15	.	.	PROPN
dti-2277	125	16	2006	2006	NUM
dti-2277	125	17	;	;	PUNCT
dti-2277	125	18	nakagawa	nakagawa	PROPN
dti-2277	125	19	et	et	PROPN
dti-2277	125	20	al	al	PROPN
dti-2277	125	21	.	.	PROPN
dti-2277	125	22	2004	2004	NUM
dti-2277	125	23	;	;	PUNCT
dti-2277	125	24	paeshuyse	paeshuyse	NOUN
dti-2277	125	25	et	et	PROPN
dti-2277	125	26	al	al	PROPN
dti-2277	125	27	.	.	PROPN
dti-2277	125	28	2006	2006	NUM
dti-2277	125	29	)	)	PUNCT
dti-2277	125	30	.	.	PUNCT
dti-2277	126	1	as	as	SCONJ
dti-2277	126	2	shown	show	VERB
dti-2277	126	3	in	in	ADP
dti-2277	126	4	fig.1a	fig.1a	ADJ
dti-2277	126	5	,	,	PUNCT
dti-2277	126	6	cellular	cellular	ADJ
dti-2277	126	7	treatment	treatment	NOUN
dti-2277	126	8	with	with	ADP
dti-2277	126	9	1	1	NUM
dti-2277	126	10	µg	µg	NOUN
dti-2277	126	11	/	/	SYM
dti-2277	126	12	ml	ml	NOUN
dti-2277	126	13	csa	csa	PROPN
dti-2277	126	14	decreases	decrease	NOUN
dti-2277	126	15	hcv	hcv	PROPN
dti-2277	126	16	rna	rna	NOUN
dti-2277	126	17	levels	level	NOUN
dti-2277	126	18	by	by	ADP
dti-2277	126	19	approximately	approximately	ADV
dti-2277	126	20	1/500	1/500	NUM
dti-2277	126	21	(	(	PUNCT
dti-2277	126	22	watashi	watashi	NOUN
dti-2277	126	23	et	et	PROPN
dti-2277	126	24	al	al	PROPN
dti-2277	126	25	.	.	PROPN
dti-2277	126	26	2003	2003	NUM
dti-2277	126	27	)	)	PUNCT
dti-2277	126	28	.	.	PUNCT
dti-2277	127	1	csa	csa	PROPN
dti-2277	127	2	also	also	ADV
dti-2277	127	3	reduces	reduce	VERB
dti-2277	127	4	the	the	DET
dti-2277	127	5	expression	expression	NOUN
dti-2277	127	6	of	of	ADP
dti-2277	127	7	hcv	hcv	NOUN
dti-2277	127	8	-	-	PUNCT
dti-2277	127	9	encoded	encode	VERB
dti-2277	127	10	proteins	protein	NOUN
dti-2277	127	11	to	to	ADP
dti-2277	127	12	undetectable	undetectable	ADJ
dti-2277	127	13	levels	level	NOUN
dti-2277	127	14	(	(	PUNCT
dti-2277	127	15	fig	fig	NOUN
dti-2277	127	16	.	.	PUNCT
dti-2277	127	17	1b	1b	NUM
dti-2277	127	18	)	)	PUNCT
dti-2277	127	19	.	.	PUNCT
dti-2277	128	1	in	in	ADP
dti-2277	128	2	contrast	contrast	NOUN
dti-2277	128	3	,	,	PUNCT
dti-2277	128	4	fk506	fk506	PROPN
dti-2277	128	5	has	have	VERB
dti-2277	128	6	no	no	DET
dti-2277	128	7	effect	effect	NOUN
dti-2277	128	8	on	on	ADP
dti-2277	128	9	the	the	DET
dti-2277	128	10	production	production	NOUN
dti-2277	128	11	of	of	ADP
dti-2277	128	12	hcv	hcv	PROPN
dti-2277	128	13	rna	rna	NOUN
dti-2277	128	14	or	or	CCONJ
dti-2277	128	15	proteins	protein	NOUN
dti-2277	128	16	(	(	PUNCT
dti-2277	128	17	fig	fig	NOUN
dti-2277	128	18	.	.	PUNCT
dti-2277	129	1	1a	1a	PROPN
dti-2277	129	2	and	and	CCONJ
dti-2277	129	3	b	b	X
dti-2277	129	4	)	)	PUNCT
dti-2277	129	5	.	.	PUNCT
dti-2277	130	1	the	the	DET
dti-2277	130	2	differences	difference	NOUN
dti-2277	130	3	between	between	ADP
dti-2277	130	4	csa	csa	PROPN
dti-2277	130	5	and	and	CCONJ
dti-2277	130	6	fk506	fk506	PROPN
dti-2277	130	7	suggest	suggest	VERB
dti-2277	130	8	that	that	SCONJ
dti-2277	130	9	csa	csa	PROPN
dti-2277	130	10	prevents	prevent	VERB
dti-2277	130	11	viral	viral	ADJ
dti-2277	130	12	genome	genome	NOUN
dti-2277	130	13	replication	replication	NOUN
dti-2277	130	14	independently	independently	ADV
dti-2277	130	15	of	of	ADP
dti-2277	130	16	cn	cn	PROPN
dti-2277	130	17	,	,	PUNCT
dti-2277	130	18	an	an	DET
dti-2277	130	19	effector	effector	NOUN
dti-2277	130	20	(	(	PUNCT
dti-2277	130	21	co	co	X
dti-2277	130	22	p	p	NOUN
dti-2277	130	23	y/	y/	NOUN
dti-2277	130	24	p	p	X
dti-2277	130	25	g	g	NOUN
dti-2277	130	26	t	t	X
dti-2277	130	27	o	o	X
dti-2277	130	28	ta	ta	ADP
dti-2277	130	29	l	l	NOUN
dti-2277	130	30	r	r	NOUN
dti-2277	131	1	n	n	NOUN
dti-2277	131	2	a	a	PRON
dti-2277	131	3	)	)	PUNCT
dti-2277	131	4	am	be	AUX
dti-2277	131	5	o	o	NOUN
dti-2277	131	6	u	u	NOUN
dti-2277	131	7	n	n	ADP
dti-2277	131	8	t	t	NOUN
dti-2277	132	1	o	o	X
dti-2277	132	2	f	f	NOUN
dti-2277	132	3	h	h	NOUN
dti-2277	132	4	c	c	NOUN
dti-2277	132	5	v	v	NOUN
dti-2277	132	6	r	r	NOUN
dti-2277	132	7	n	n	NOUN
dti-2277	132	8	a	a	DET
dti-2277	132	9	figure	figure	NOUN
dti-2277	132	10	.	.	PUNCT
dti-2277	133	1	1	1	NUM
dti-2277	133	2	csa	csa	PROPN
dti-2277	133	3	suppresses	suppress	VERB
dti-2277	133	4	hcv	hcv	VERB
dti-2277	133	5	genome	genome	NOUN
dti-2277	133	6	replication	replication	NOUN
dti-2277	133	7	.	.	PUNCT
dti-2277	134	1	(	(	PUNCT
dti-2277	134	2	a	a	X
dti-2277	134	3	)	)	PUNCT
dti-2277	134	4	hcv	hcv	PROPN
dti-2277	134	5	rna	rna	NOUN
dti-2277	134	6	was	be	AUX
dti-2277	134	7	quantifi	quantifi	ADJ
dti-2277	134	8	ed	ed	NOUN
dti-2277	134	9	in	in	ADP
dti-2277	134	10	total	total	ADJ
dti-2277	134	11	rna	rna	NOUN
dti-2277	134	12	isolated	isolate	VERB
dti-2277	134	13	from	from	ADP
dti-2277	134	14	hcv	hcv	ADJ
dti-2277	134	15	replicon	replicon	NOUN
dti-2277	134	16	-	-	PUNCT
dti-2277	134	17	bearing	bear	VERB
dti-2277	134	18	cells	cell	NOUN
dti-2277	134	19	treated	treat	VERB
dti-2277	134	20	with	with	ADP
dti-2277	134	21	various	various	ADJ
dti-2277	134	22	concentrations	concentration	NOUN
dti-2277	134	23	of	of	ADP
dti-2277	134	24	csa	csa	PROPN
dti-2277	134	25	,	,	PUNCT
dti-2277	134	26	fk506	fk506	PROPN
dti-2277	134	27	,	,	PUNCT
dti-2277	134	28	or	or	CCONJ
dti-2277	134	29	ifnα	ifnα	VERB
dti-2277	134	30	for	for	ADP
dti-2277	134	31	7	7	NUM
dti-2277	134	32	days	day	NOUN
dti-2277	134	33	.	.	PUNCT
dti-2277	135	1	the	the	DET
dti-2277	135	2	amount	amount	NOUN
dti-2277	135	3	of	of	ADP
dti-2277	135	4	hcv	hcv	PROPN
dti-2277	135	5	rna	rna	NOUN
dti-2277	135	6	per	per	ADP
dti-2277	135	7	1	1	NUM
dti-2277	135	8	pg	pg	PROPN
dti-2277	135	9	total	total	PROPN
dti-2277	135	10	rna	rna	PROPN
dti-2277	135	11	was	be	AUX
dti-2277	135	12	plotted	plot	VERB
dti-2277	135	13	against	against	ADP
dti-2277	135	14	the	the	DET
dti-2277	135	15	concentration	concentration	NOUN
dti-2277	135	16	of	of	ADP
dti-2277	135	17	csa	csa	PROPN
dti-2277	135	18	(	(	PUNCT
dti-2277	135	19	µg	µg	NOUN
dti-2277	135	20	/	/	SYM
dti-2277	135	21	ml	ml	NOUN
dti-2277	135	22	)	)	PUNCT
dti-2277	135	23	,	,	PUNCT
dti-2277	135	24	fk506	fk506	NOUN
dti-2277	135	25	(	(	PUNCT
dti-2277	135	26	µg	µg	NOUN
dti-2277	135	27	/	/	SYM
dti-2277	135	28	ml	ml	NOUN
dti-2277	135	29	)	)	PUNCT
dti-2277	135	30	,	,	PUNCT
dti-2277	135	31	or	or	CCONJ
dti-2277	135	32	ifnα	ifnα	ADJ
dti-2277	135	33	(	(	PUNCT
dti-2277	135	34	×	×	PROPN
dti-2277	135	35	100	100	NUM
dti-2277	135	36	iu	iu	NOUN
dti-2277	135	37	/	/	SYM
dti-2277	135	38	ml	ml	NOUN
dti-2277	135	39	)	)	PUNCT
dti-2277	135	40	.	.	PUNCT
dti-2277	136	1	(	(	PUNCT
dti-2277	136	2	b	b	X
dti-2277	136	3	)	)	PUNCT
dti-2277	136	4	the	the	DET
dti-2277	136	5	expression	expression	NOUN
dti-2277	136	6	of	of	ADP
dti-2277	136	7	hcv	hcv	PROPN
dti-2277	136	8	ns5a	ns5a	NOUN
dti-2277	136	9	and	and	CCONJ
dti-2277	136	10	protein	protein	NOUN
dti-2277	136	11	disulfi	disulfi	NOUN
dti-2277	136	12	de	de	X
dti-2277	136	13	isomerase	isomerase	NOUN
dti-2277	136	14	(	(	PUNCT
dti-2277	136	15	pdi	pdi	PROPN
dti-2277	136	16	)	)	PUNCT
dti-2277	136	17	as	as	ADP
dti-2277	136	18	a	a	DET
dti-2277	136	19	cellular	cellular	ADJ
dti-2277	136	20	protein	protein	NOUN
dti-2277	136	21	was	be	AUX
dti-2277	136	22	examined	examine	VERB
dti-2277	136	23	in	in	ADP
dti-2277	136	24	the	the	DET
dti-2277	136	25	hcv	hcv	PROPN
dti-2277	136	26	replicon	replicon	NOUN
dti-2277	136	27	-	-	PUNCT
dti-2277	136	28	bearing	bear	VERB
dti-2277	136	29	cells	cell	NOUN
dti-2277	136	30	treated	treat	VERB
dti-2277	136	31	without	without	ADP
dti-2277	136	32	(	(	PUNCT
dti-2277	136	33	control	control	NOUN
dti-2277	136	34	)	)	PUNCT
dti-2277	136	35	or	or	CCONJ
dti-2277	136	36	with	with	ADP
dti-2277	136	37	100	100	NUM
dti-2277	136	38	iu	iu	NOUN
dti-2277	136	39	/	/	SYM
dti-2277	136	40	ml	ml	NOUN
dti-2277	136	41	ifnα	ifnα	ADJ
dti-2277	136	42	,	,	PUNCT
dti-2277	136	43	1	1	NUM
dti-2277	136	44	�	�	NOUN
dti-2277	136	45	µg	µg	NOUN
dti-2277	136	46	/	/	SYM
dti-2277	136	47	ml	ml	X
dti-2277	136	48	csa	csa	PROPN
dti-2277	136	49	,	,	PUNCT
dti-2277	136	50	or	or	CCONJ
dti-2277	136	51	1	1	NUM
dti-2277	136	52	�	�	NOUN
dti-2277	136	53	µg	µg	NOUN
dti-2277	136	54	/	/	SYM
dti-2277	136	55	ml	ml	ADP
dti-2277	136	56	fk506	fk506	NOUN
dti-2277	136	57	for	for	ADP
dti-2277	136	58	7	7	NUM
dti-2277	136	59	days	day	NOUN
dti-2277	136	60	.	.	PUNCT
dti-2277	137	1	drug	drug	NOUN
dti-2277	137	2	target	target	NOUN
dti-2277	137	3	insights	insight	NOUN
dti-2277	137	4	2007	2007	NUM
dti-2277	137	5	:	:	PUNCT
dti-2277	137	6	2	2	NUM
dti-2277	137	7	14	14	NUM
dti-2277	137	8	watashi	watashi	NOUN
dti-2277	137	9	and	and	CCONJ
dti-2277	137	10	shimotohno	shimotohno	NOUN
dti-2277	137	11	common	common	ADJ
dti-2277	137	12	to	to	ADP
dti-2277	137	13	both	both	CCONJ
dti-2277	137	14	csa	csa	PROPN
dti-2277	137	15	and	and	CCONJ
dti-2277	137	16	fk506	fk506	NOUN
dti-2277	137	17	mediated	mediate	VERB
dti-2277	137	18	immunosuppression	immunosuppression	NOUN
dti-2277	137	19	.	.	PUNCT
dti-2277	138	1	and	and	CCONJ
dti-2277	138	2	the	the	DET
dti-2277	138	3	anti	anti	ADJ
dti-2277	138	4	-	-	ADJ
dti-2277	138	5	hcv	hcv	ADJ
dti-2277	138	6	effects	effect	NOUN
dti-2277	138	7	of	of	ADP
dti-2277	138	8	csa	csa	PROPN
dti-2277	138	9	are	be	AUX
dti-2277	138	10	mediated	mediate	VERB
dti-2277	138	11	by	by	ADP
dti-2277	138	12	pathway(s	pathway(s	NOUN
dti-2277	138	13	)	)	PUNCT
dti-2277	138	14	distinct	distinct	NOUN
dti-2277	138	15	from	from	ADP
dti-2277	138	16	those	those	PRON
dti-2277	138	17	of	of	ADP
dti-2277	138	18	ifnα	ifnα	PROPN
dti-2277	138	19	(	(	PUNCT
dti-2277	138	20	watashi	watashi	NOUN
dti-2277	138	21	et	et	PROPN
dti-2277	138	22	al	al	PROPN
dti-2277	138	23	.	.	PROPN
dti-2277	138	24	2003	2003	NUM
dti-2277	138	25	)	)	PUNCT
dti-2277	138	26	.	.	PUNCT
dti-2277	139	1	cypb	cypb	PROPN
dti-2277	139	2	as	as	ADP
dti-2277	139	3	a	a	DET
dti-2277	139	4	cellular	cellular	ADJ
dti-2277	139	5	cofactor	cofactor	NOUN
dti-2277	139	6	of	of	ADP
dti-2277	139	7	hcv	hcv	NOUN
dti-2277	139	8	genome	genome	NOUN
dti-2277	139	9	replication	replication	NOUN
dti-2277	139	10	the	the	DET
dti-2277	139	11	ability	ability	NOUN
dti-2277	139	12	of	of	ADP
dti-2277	139	13	csa	csa	PROPN
dti-2277	139	14	to	to	PART
dti-2277	139	15	inhibit	inhibit	VERB
dti-2277	139	16	hcv	hcv	NOUN
dti-2277	139	17	genome	genome	NOUN
dti-2277	139	18	replication	replication	NOUN
dti-2277	139	19	correlates	correlate	VERB
dti-2277	139	20	with	with	ADP
dti-2277	139	21	the	the	DET
dti-2277	139	22	inhibition	inhibition	NOUN
dti-2277	139	23	of	of	ADP
dti-2277	139	24	cyp	cyp	ADJ
dti-2277	139	25	activity	activity	NOUN
dti-2277	139	26	(	(	PUNCT
dti-2277	139	27	watashi	watashi	NOUN
dti-2277	139	28	et	et	PROPN
dti-2277	139	29	al	al	PROPN
dti-2277	139	30	.	.	PROPN
dti-2277	139	31	2005	2005	NUM
dti-2277	139	32	)	)	PUNCT
dti-2277	139	33	.	.	PUNCT
dti-2277	140	1	moreover	moreover	ADV
dti-2277	140	2	,	,	PUNCT
dti-2277	140	3	an	an	DET
dti-2277	140	4	alternative	alternative	ADJ
dti-2277	140	5	cyp	cyp	ADJ
dti-2277	140	6	inhibitor	inhibitor	NOUN
dti-2277	140	7	,	,	PUNCT
dti-2277	140	8	sanglifehrin	sanglifehrin	NOUN
dti-2277	140	9	,	,	PUNCT
dti-2277	140	10	also	also	ADV
dti-2277	140	11	decreases	decrease	VERB
dti-2277	140	12	the	the	DET
dti-2277	140	13	levels	level	NOUN
dti-2277	140	14	of	of	ADP
dti-2277	140	15	hcv	hcv	PROPN
dti-2277	140	16	rna	rna	PROPN
dti-2277	140	17	.	.	PUNCT
dti-2277	141	1	thus	thus	ADV
dti-2277	141	2	,	,	PUNCT
dti-2277	141	3	the	the	DET
dti-2277	141	4	inhibition	inhibition	NOUN
dti-2277	141	5	of	of	ADP
dti-2277	141	6	cyp	cyp	ADJ
dti-2277	141	7	activity	activity	NOUN
dti-2277	141	8	is	be	AUX
dti-2277	141	9	essential	essential	ADJ
dti-2277	141	10	for	for	ADP
dti-2277	141	11	the	the	DET
dti-2277	141	12	anti	anti	ADJ
dti-2277	141	13	-	-	ADJ
dti-2277	141	14	hcv	hcv	ADJ
dti-2277	141	15	effect	effect	NOUN
dti-2277	141	16	of	of	ADP
dti-2277	141	17	csa	csa	PROPN
dti-2277	141	18	,	,	PUNCT
dti-2277	141	19	and	and	CCONJ
dti-2277	141	20	this	this	PRON
dti-2277	141	21	strongly	strongly	ADV
dti-2277	141	22	suggests	suggest	VERB
dti-2277	141	23	that	that	SCONJ
dti-2277	141	24	cyp	cyp	ADJ
dti-2277	141	25	plays	play	VERB
dti-2277	141	26	a	a	DET
dti-2277	141	27	direct	direct	ADJ
dti-2277	141	28	,	,	PUNCT
dti-2277	141	29	important	important	ADJ
dti-2277	141	30	role	role	NOUN
dti-2277	141	31	in	in	ADP
dti-2277	141	32	hcv	hcv	NOUN
dti-2277	141	33	genome	genome	NOUN
dti-2277	141	34	replication	replication	NOUN
dti-2277	141	35	.	.	PUNCT
dti-2277	142	1	moreover	moreover	ADV
dti-2277	142	2	,	,	PUNCT
dti-2277	142	3	the	the	DET
dti-2277	142	4	specifi	specifi	PROPN
dti-2277	142	5	c	c	PROPN
dti-2277	142	6	knockdown	knockdown	NOUN
dti-2277	142	7	of	of	ADP
dti-2277	142	8	cypb	cypb	PROPN
dti-2277	142	9	by	by	ADP
dti-2277	142	10	rnai	rnai	PROPN
dti-2277	142	11	reduced	reduce	VERB
dti-2277	142	12	hcv	hcv	PROPN
dti-2277	142	13	rna	rna	NOUN
dti-2277	142	14	titer	titer	NOUN
dti-2277	142	15	,	,	PUNCT
dti-2277	142	16	but	but	CCONJ
dti-2277	142	17	knockdown	knockdown	NOUN
dti-2277	142	18	of	of	ADP
dti-2277	142	19	cypa	cypa	PROPN
dti-2277	142	20	,	,	PUNCT
dti-2277	142	21	cypc	cypc	NOUN
dti-2277	142	22	,	,	PUNCT
dti-2277	142	23	cype	cype	NOUN
dti-2277	142	24	,	,	PUNCT
dti-2277	142	25	or	or	CCONJ
dti-2277	142	26	cyph	cyph	NOUN
dti-2277	142	27	had	have	VERB
dti-2277	142	28	no	no	DET
dti-2277	142	29	effect	effect	NOUN
dti-2277	142	30	on	on	ADP
dti-2277	142	31	hcv	hcv	NOUN
dti-2277	142	32	replication	replication	NOUN
dti-2277	142	33	activity	activity	NOUN
dti-2277	142	34	.	.	PUNCT
dti-2277	143	1	these	these	DET
dti-2277	143	2	data	datum	NOUN
dti-2277	143	3	indicate	indicate	VERB
dti-2277	143	4	that	that	SCONJ
dti-2277	143	5	cypb	cypb	NOUN
dti-2277	143	6	plays	play	VERB
dti-2277	143	7	a	a	DET
dti-2277	143	8	critical	critical	ADJ
dti-2277	143	9	role	role	NOUN
dti-2277	143	10	in	in	ADP
dti-2277	143	11	hcv	hcv	NOUN
dti-2277	143	12	genome	genome	NOUN
dti-2277	143	13	replication	replication	NOUN
dti-2277	143	14	.	.	PUNCT
dti-2277	144	1	regulation	regulation	NOUN
dti-2277	144	2	of	of	ADP
dti-2277	144	3	ns5b	ns5b	PROPN
dti-2277	144	4	by	by	ADP
dti-2277	144	5	cypb	cypb	NOUN
dti-2277	144	6	the	the	DET
dti-2277	144	7	effects	effect	NOUN
dti-2277	144	8	of	of	ADP
dti-2277	144	9	cypb	cypb	NOUN
dti-2277	144	10	on	on	ADP
dti-2277	144	11	hcv	hcv	NOUN
dti-2277	144	12	genome	genome	NOUN
dti-2277	144	13	replication	replication	NOUN
dti-2277	144	14	are	be	AUX
dti-2277	144	15	mediated	mediate	VERB
dti-2277	144	16	through	through	ADP
dti-2277	144	17	a	a	DET
dti-2277	144	18	direct	direct	ADJ
dti-2277	144	19	interaction	interaction	NOUN
dti-2277	144	20	with	with	ADP
dti-2277	144	21	ns5b	ns5b	PROPN
dti-2277	144	22	as	as	SCONJ
dti-2277	144	23	demonstrated	demonstrate	VERB
dti-2277	144	24	in	in	ADP
dti-2277	144	25	both	both	PRON
dti-2277	144	26	in	in	ADP
dti-2277	144	27	vitro	vitro	X
dti-2277	144	28	and	and	CCONJ
dti-2277	144	29	in	in	ADP
dti-2277	144	30	cells	cell	NOUN
dti-2277	144	31	(	(	PUNCT
dti-2277	144	32	watashi	watashi	NOUN
dti-2277	144	33	et	et	PROPN
dti-2277	144	34	al	al	PROPN
dti-2277	144	35	.	.	PROPN
dti-2277	144	36	2005	2005	NUM
dti-2277	144	37	)	)	PUNCT
dti-2277	144	38	(	(	PUNCT
dti-2277	144	39	fig	fig	NOUN
dti-2277	144	40	.	.	PUNCT
dti-2277	145	1	2a	2a	NUM
dti-2277	145	2	)	)	PUNCT
dti-2277	145	3	.	.	PUNCT
dti-2277	146	1	cypb	cypb	PROPN
dti-2277	146	2	do	do	AUX
dti-2277	146	3	not	not	PART
dti-2277	146	4	bind	bind	VERB
dti-2277	146	5	any	any	DET
dti-2277	146	6	other	other	ADJ
dti-2277	146	7	hcv	hcv	NOUN
dti-2277	146	8	proteins	protein	NOUN
dti-2277	146	9	involved	involve	VERB
dti-2277	146	10	in	in	ADP
dti-2277	146	11	viral	viral	ADJ
dti-2277	146	12	replication	replication	NOUN
dti-2277	146	13	.	.	PUNCT
dti-2277	147	1	ns5b	ns5b	PROPN
dti-2277	147	2	binds	bind	VERB
dti-2277	147	3	hcv	hcv	NOUN
dti-2277	147	4	genome	genome	NOUN
dti-2277	147	5	rna	rna	NOUN
dti-2277	147	6	in	in	ADP
dti-2277	147	7	order	order	NOUN
dti-2277	147	8	to	to	PART
dti-2277	147	9	function	function	VERB
dti-2277	147	10	as	as	ADP
dti-2277	147	11	a	a	DET
dti-2277	147	12	rdrp	rdrp	NOUN
dti-2277	147	13	.	.	PUNCT
dti-2277	148	1	cypb	cypb	PROPN
dti-2277	148	2	but	but	CCONJ
dti-2277	148	3	not	not	PART
dti-2277	148	4	cypa	cypa	INTJ
dti-2277	148	5	promotes	promote	VERB
dti-2277	148	6	the	the	DET
dti-2277	148	7	rna	rna	NOUN
dti-2277	148	8	binding	bind	VERB
dti-2277	148	9	activity	activity	NOUN
dti-2277	148	10	of	of	ADP
dti-2277	148	11	ns5b	ns5b	PROPN
dti-2277	148	12	and	and	CCONJ
dti-2277	148	13	stimulates	stimulate	VERB
dti-2277	148	14	hcv	hcv	VERB
dti-2277	148	15	genome	genome	NOUN
dti-2277	148	16	replication	replication	NOUN
dti-2277	148	17	in	in	ADP
dti-2277	148	18	cells	cell	NOUN
dti-2277	148	19	(	(	PUNCT
dti-2277	148	20	fig	fig	NOUN
dti-2277	148	21	.	.	PUNCT
dti-2277	149	1	2a	2a	NUM
dti-2277	149	2	)	)	PUNCT
dti-2277	149	3	.	.	PUNCT
dti-2277	150	1	this	this	DET
dti-2277	150	2	functional	functional	ADJ
dti-2277	150	3	support	support	NOUN
dti-2277	150	4	by	by	ADP
dti-2277	150	5	cypb	cypb	NOUN
dti-2277	150	6	to	to	ADP
dti-2277	150	7	ns5b	ns5b	PROPN
dti-2277	150	8	is	be	AUX
dti-2277	150	9	essential	essential	ADJ
dti-2277	150	10	for	for	ADP
dti-2277	150	11	the	the	DET
dti-2277	150	12	effi	effi	PROPN
dti-2277	150	13	cient	cient	NOUN
dti-2277	150	14	replication	replication	NOUN
dti-2277	150	15	of	of	ADP
dti-2277	150	16	the	the	DET
dti-2277	150	17	hcv	hcv	NOUN
dti-2277	150	18	genome	genome	NOUN
dti-2277	150	19	,	,	PUNCT
dti-2277	150	20	and	and	CCONJ
dti-2277	150	21	csa	csa	PROPN
dti-2277	150	22	blocks	block	VERB
dti-2277	150	23	the	the	DET
dti-2277	150	24	interaction	interaction	NOUN
dti-2277	150	25	of	of	ADP
dti-2277	150	26	cypb	cypb	NOUN
dti-2277	150	27	with	with	ADP
dti-2277	150	28	ns5b	ns5b	PROPN
dti-2277	150	29	,	,	PUNCT
dti-2277	150	30	leading	lead	VERB
dti-2277	150	31	to	to	ADP
dti-2277	150	32	reduced	reduce	VERB
dti-2277	150	33	rna	rna	NOUN
dti-2277	150	34	binding	bind	VERB
dti-2277	150	35	(	(	PUNCT
dti-2277	150	36	fig	fig	NOUN
dti-2277	150	37	.	.	PUNCT
dti-2277	150	38	2b	2b	NUM
dti-2277	150	39	)	)	PUNCT
dti-2277	150	40	.	.	PUNCT
dti-2277	151	1	figure	figure	NOUN
dti-2277	151	2	.	.	PUNCT
dti-2277	152	1	2	2	NUM
dti-2277	152	2	cypb	cypb	NOUN
dti-2277	152	3	regulates	regulate	VERB
dti-2277	152	4	the	the	DET
dti-2277	152	5	activity	activity	NOUN
dti-2277	152	6	of	of	ADP
dti-2277	152	7	ns5b	ns5b	PROPN
dti-2277	152	8	.	.	PUNCT
dti-2277	153	1	(	(	PUNCT
dti-2277	153	2	a	a	X
dti-2277	153	3	)	)	PUNCT
dti-2277	153	4	in	in	ADP
dti-2277	153	5	the	the	DET
dti-2277	153	6	absence	absence	NOUN
dti-2277	153	7	of	of	ADP
dti-2277	153	8	csa	csa	PROPN
dti-2277	153	9	(	(	PUNCT
dti-2277	153	10	normal	normal	ADJ
dti-2277	153	11	conditions	condition	NOUN
dti-2277	153	12	)	)	PUNCT
dti-2277	153	13	,	,	PUNCT
dti-2277	153	14	ns5b	ns5b	PROPN
dti-2277	153	15	associates	associate	NOUN
dti-2277	153	16	with	with	ADP
dti-2277	153	17	cellular	cellular	ADJ
dti-2277	153	18	cypb	cypb	NOUN
dti-2277	153	19	to	to	ADP
dti-2277	153	20	effi	effi	PROPN
dti-2277	153	21	ciently	ciently	ADV
dti-2277	153	22	bind	bind	VERB
dti-2277	153	23	to	to	ADP
dti-2277	153	24	the	the	DET
dti-2277	153	25	hcv	hcv	NOUN
dti-2277	153	26	genome	genome	NOUN
dti-2277	153	27	rna	rna	NOUN
dti-2277	153	28	and	and	CCONJ
dti-2277	153	29	drive	drive	VERB
dti-2277	153	30	genome	genome	NOUN
dti-2277	153	31	replication	replication	NOUN
dti-2277	153	32	.	.	PUNCT
dti-2277	154	1	(	(	PUNCT
dti-2277	154	2	b	b	X
dti-2277	154	3	)	)	PUNCT
dti-2277	154	4	in	in	ADP
dti-2277	154	5	the	the	DET
dti-2277	154	6	presence	presence	NOUN
dti-2277	154	7	of	of	ADP
dti-2277	154	8	csa	csa	PROPN
dti-2277	154	9	,	,	PUNCT
dti-2277	154	10	cypb	cypb	PROPN
dti-2277	154	11	does	do	AUX
dti-2277	154	12	not	not	PART
dti-2277	154	13	interact	interact	VERB
dti-2277	154	14	with	with	ADP
dti-2277	154	15	ns5b	ns5b	PROPN
dti-2277	154	16	.	.	PUNCT
dti-2277	155	1	free	free	ADJ
dti-2277	155	2	ns5b	ns5b	PROPN
dti-2277	155	3	less	less	ADJ
dti-2277	155	4	functions	function	NOUN
dti-2277	155	5	,	,	PUNCT
dti-2277	155	6	and	and	CCONJ
dti-2277	155	7	viral	viral	ADJ
dti-2277	155	8	genome	genome	NOUN
dti-2277	155	9	replication	replication	NOUN
dti-2277	155	10	is	be	AUX
dti-2277	155	11	impaired	impair	VERB
dti-2277	155	12	in	in	ADP
dti-2277	155	13	the	the	DET
dti-2277	155	14	absence	absence	NOUN
dti-2277	155	15	of	of	ADP
dti-2277	155	16	functional	functional	ADJ
dti-2277	155	17	cypb	cypb	NOUN
dti-2277	155	18	.	.	PUNCT
dti-2277	156	1	drug	drug	NOUN
dti-2277	156	2	target	target	NOUN
dti-2277	156	3	insights	insight	NOUN
dti-2277	156	4	2007	2007	NUM
dti-2277	156	5	:	:	PUNCT
dti-2277	156	6	2	2	NUM
dti-2277	156	7	15	15	NUM
dti-2277	156	8	cyclophilin	cyclophilin	NOUN
dti-2277	156	9	and	and	CCONJ
dti-2277	156	10	viruses	virus	NOUN
dti-2277	156	11	thus	thus	ADV
dti-2277	156	12	,	,	PUNCT
dti-2277	156	13	cypb	cypb	NOUN
dti-2277	156	14	serves	serve	VERB
dti-2277	156	15	as	as	ADP
dti-2277	156	16	a	a	DET
dti-2277	156	17	cellular	cellular	ADJ
dti-2277	156	18	cofactor	cofactor	NOUN
dti-2277	156	19	for	for	ADP
dti-2277	156	20	hcv	hcv	NOUN
dti-2277	156	21	genome	genome	NOUN
dti-2277	156	22	replication	replication	NOUN
dti-2277	156	23	.	.	PUNCT
dti-2277	157	1	therapeutic	therapeutic	ADJ
dti-2277	157	2	implications	implication	NOUN
dti-2277	157	3	of	of	ADP
dti-2277	157	4	cyp	cyp	ADJ
dti-2277	157	5	inhibition	inhibition	NOUN
dti-2277	157	6	for	for	ADP
dti-2277	157	7	the	the	DET
dti-2277	157	8	treatment	treatment	NOUN
dti-2277	157	9	for	for	ADP
dti-2277	157	10	hcv	hcv	X
dti-2277	157	11	the	the	DET
dti-2277	157	12	anti	anti	ADJ
dti-2277	157	13	-	-	ADJ
dti-2277	157	14	hcv	hcv	ADJ
dti-2277	157	15	activity	activity	NOUN
dti-2277	157	16	of	of	ADP
dti-2277	157	17	csa	csa	PROPN
dti-2277	157	18	analogs	analogs	PROPN
dti-2277	157	19	correlates	correlate	VERB
dti-2277	157	20	with	with	ADP
dti-2277	157	21	their	their	PRON
dti-2277	157	22	ability	ability	NOUN
dti-2277	157	23	to	to	PART
dti-2277	157	24	inhibit	inhibit	VERB
dti-2277	157	25	cyp	cyp	ADJ
dti-2277	157	26	function	function	NOUN
dti-2277	157	27	(	(	PUNCT
dti-2277	157	28	watashi	watashi	NOUN
dti-2277	157	29	et	et	PROPN
dti-2277	157	30	al	al	PROPN
dti-2277	157	31	.	.	PROPN
dti-2277	157	32	2005	2005	NUM
dti-2277	157	33	)	)	PUNCT
dti-2277	157	34	.	.	PUNCT
dti-2277	158	1	the	the	DET
dti-2277	158	2	dissociation	dissociation	NOUN
dti-2277	158	3	of	of	ADP
dti-2277	158	4	cypb	cypb	PROPN
dti-2277	158	5	and	and	CCONJ
dti-2277	158	6	ns5b	ns5b	PROPN
dti-2277	158	7	greatly	greatly	ADV
dti-2277	158	8	reduces	reduce	VERB
dti-2277	158	9	the	the	DET
dti-2277	158	10	extent	extent	NOUN
dti-2277	158	11	of	of	ADP
dti-2277	158	12	hcv	hcv	NOUN
dti-2277	158	13	genome	genome	NOUN
dti-2277	158	14	replication	replication	NOUN
dti-2277	158	15	.	.	PUNCT
dti-2277	159	1	these	these	DET
dti-2277	159	2	observations	observation	NOUN
dti-2277	159	3	suggest	suggest	VERB
dti-2277	159	4	that	that	SCONJ
dti-2277	159	5	the	the	DET
dti-2277	159	6	inhibition	inhibition	NOUN
dti-2277	159	7	of	of	ADP
dti-2277	159	8	cypb	cypb	NOUN
dti-2277	159	9	may	may	AUX
dti-2277	159	10	represent	represent	VERB
dti-2277	159	11	a	a	DET
dti-2277	159	12	novel	novel	ADJ
dti-2277	159	13	therapeutic	therapeutic	ADJ
dti-2277	159	14	strategy	strategy	NOUN
dti-2277	159	15	against	against	ADP
dti-2277	159	16	hcv	hcv	PROPN
dti-2277	159	17	.	.	PUNCT
dti-2277	160	1	this	this	DET
dti-2277	160	2	possibility	possibility	NOUN
dti-2277	160	3	has	have	AUX
dti-2277	160	4	been	be	AUX
dti-2277	160	5	examined	examine	VERB
dti-2277	160	6	by	by	ADP
dti-2277	160	7	two	two	NUM
dti-2277	160	8	reports	report	NOUN
dti-2277	160	9	using	use	VERB
dti-2277	160	10	stronger	strong	ADJ
dti-2277	160	11	cyp	cyp	ADJ
dti-2277	160	12	inhibitors	inhibitor	NOUN
dti-2277	160	13	than	than	ADP
dti-2277	160	14	csa	csa	PROPN
dti-2277	160	15	.	.	PROPN
dti-2277	161	1	paeshuyse	paeshuyse	PROPN
dti-2277	161	2	et	et	PROPN
dti-2277	161	3	al	al	PROPN
dti-2277	161	4	.	.	PROPN
dti-2277	161	5	used	use	VERB
dti-2277	161	6	the	the	DET
dti-2277	161	7	csa	csa	PROPN
dti-2277	161	8	analog	analog	PROPN
dti-2277	161	9	debio-025	debio-025	NOUN
dti-2277	161	10	to	to	PART
dti-2277	161	11	inhibit	inhibit	VERB
dti-2277	161	12	cyp	cyp	ADJ
dti-2277	161	13	activity	activity	NOUN
dti-2277	161	14	(	(	PUNCT
dti-2277	161	15	paeshuyse	paeshuyse	NOUN
dti-2277	161	16	et	et	PROPN
dti-2277	161	17	al	al	PROPN
dti-2277	161	18	.	.	PROPN
dti-2277	161	19	2006	2006	NUM
dti-2277	161	20	)	)	PUNCT
dti-2277	161	21	,	,	PUNCT
dti-2277	161	22	and	and	CCONJ
dti-2277	161	23	this	this	DET
dti-2277	161	24	compound	compound	NOUN
dti-2277	161	25	inhibited	inhibit	VERB
dti-2277	161	26	hcv	hcv	NOUN
dti-2277	161	27	replication	replication	NOUN
dti-2277	161	28	10	10	NUM
dti-2277	161	29	-	-	NUM
dti-2277	161	30	fold	fold	VERB
dti-2277	161	31	more	more	ADV
dti-2277	161	32	potently	potently	ADV
dti-2277	161	33	than	than	ADP
dti-2277	161	34	csa	csa	PROPN
dti-2277	161	35	.	.	PUNCT
dti-2277	162	1	the	the	DET
dti-2277	162	2	authors	author	NOUN
dti-2277	162	3	speculated	speculate	VERB
dti-2277	162	4	that	that	SCONJ
dti-2277	162	5	debio-025	debio-025	NOUN
dti-2277	162	6	might	might	AUX
dti-2277	162	7	be	be	AUX
dti-2277	162	8	an	an	DET
dti-2277	162	9	attractive	attractive	ADJ
dti-2277	162	10	drug	drug	NOUN
dti-2277	162	11	candidate	candidate	NOUN
dti-2277	162	12	for	for	ADP
dti-2277	162	13	the	the	DET
dti-2277	162	14	treatment	treatment	NOUN
dti-2277	162	15	of	of	ADP
dti-2277	162	16	individuals	individual	NOUN
dti-2277	162	17	with	with	ADP
dti-2277	162	18	hcv	hcv	PROPN
dti-2277	162	19	/	/	SYM
dti-2277	162	20	hiv	hiv	PROPN
dti-2277	162	21	coinfection	coinfection	NOUN
dti-2277	162	22	because	because	SCONJ
dti-2277	162	23	csa	csa	PROPN
dti-2277	162	24	derivatives	derivative	NOUN
dti-2277	162	25	should	should	AUX
dti-2277	162	26	also	also	ADV
dti-2277	162	27	inhibit	inhibit	VERB
dti-2277	162	28	hiv-1	hiv-1	ADJ
dti-2277	162	29	replication	replication	NOUN
dti-2277	162	30	.	.	PUNCT
dti-2277	163	1	we	we	PRON
dti-2277	163	2	used	use	VERB
dti-2277	163	3	the	the	DET
dti-2277	163	4	non	non	ADJ
dti-2277	163	5	-	-	ADJ
dti-2277	163	6	immunosuppressive	immunosuppressive	ADJ
dti-2277	163	7	csa	csa	PROPN
dti-2277	163	8	derivative	derivative	PROPN
dti-2277	163	9	nim811	nim811	PROPN
dti-2277	163	10	to	to	PART
dti-2277	163	11	target	target	VERB
dti-2277	163	12	cyp	cyp	ADJ
dti-2277	163	13	(	(	PUNCT
dti-2277	163	14	goto	goto	NOUN
dti-2277	163	15	et	et	PROPN
dti-2277	163	16	al	al	PROPN
dti-2277	163	17	.	.	PROPN
dti-2277	163	18	2006	2006	NUM
dti-2277	163	19	;	;	PUNCT
dti-2277	163	20	ishii	ishii	PROPN
dti-2277	163	21	et	et	PROPN
dti-2277	163	22	al	al	PROPN
dti-2277	163	23	.	.	PROPN
dti-2277	163	24	2006	2006	NUM
dti-2277	163	25	)	)	PUNCT
dti-2277	163	26	.	.	PUNCT
dti-2277	164	1	nim811	nim811	PROPN
dti-2277	164	2	inhibits	inhibit	VERB
dti-2277	164	3	cyp	cyp	ADJ
dti-2277	164	4	enzymatic	enzymatic	ADJ
dti-2277	164	5	activity	activity	NOUN
dti-2277	164	6	two	two	NUM
dti-2277	164	7	-	-	NUM
dti-2277	164	8	fold	fold	VERB
dti-2277	164	9	more	more	ADV
dti-2277	164	10	than	than	ADP
dti-2277	164	11	csa	csa	PROPN
dti-2277	164	12	(	(	PUNCT
dti-2277	164	13	rosenwirth	rosenwirth	NOUN
dti-2277	164	14	et	et	PROPN
dti-2277	164	15	al	al	PROPN
dti-2277	164	16	.	.	PROPN
dti-2277	164	17	1994	1994	NUM
dti-2277	164	18	)	)	PUNCT
dti-2277	164	19	,	,	PUNCT
dti-2277	164	20	and	and	CCONJ
dti-2277	164	21	this	this	DET
dti-2277	164	22	increased	increase	VERB
dti-2277	164	23	inhibition	inhibition	NOUN
dti-2277	164	24	correlates	correlate	VERB
dti-2277	164	25	with	with	ADP
dti-2277	164	26	greater	great	ADJ
dti-2277	164	27	suppression	suppression	NOUN
dti-2277	164	28	of	of	ADP
dti-2277	164	29	hcv	hcv	NOUN
dti-2277	164	30	genome	genome	NOUN
dti-2277	164	31	replication	replication	NOUN
dti-2277	164	32	than	than	ADP
dti-2277	164	33	csa	csa	PROPN
dti-2277	164	34	,	,	PUNCT
dti-2277	164	35	especially	especially	ADV
dti-2277	164	36	at	at	ADP
dti-2277	164	37	lower	low	ADJ
dti-2277	164	38	doses	dose	NOUN
dti-2277	164	39	.	.	PUNCT
dti-2277	165	1	cotreatment	cotreatment	NOUN
dti-2277	165	2	of	of	ADP
dti-2277	165	3	cells	cell	NOUN
dti-2277	165	4	with	with	ADP
dti-2277	165	5	nim811	nim811	PROPN
dti-2277	165	6	and	and	CCONJ
dti-2277	165	7	ifnα	ifnα	NOUN
dti-2277	165	8	led	lead	VERB
dti-2277	165	9	to	to	ADP
dti-2277	165	10	a	a	DET
dti-2277	165	11	synergistic	synergistic	ADJ
dti-2277	165	12	anti	anti	ADJ
dti-2277	165	13	-	-	ADJ
dti-2277	165	14	hcv	hcv	ADJ
dti-2277	165	15	effect	effect	NOUN
dti-2277	165	16	at	at	ADP
dti-2277	165	17	higher	high	ADJ
dti-2277	165	18	doses	dose	NOUN
dti-2277	165	19	of	of	ADP
dti-2277	165	20	nim811	nim811	PROPN
dti-2277	165	21	.	.	PUNCT
dti-2277	166	1	treatment	treatment	NOUN
dti-2277	166	2	of	of	ADP
dti-2277	166	3	nim811	nim811	PROPN
dti-2277	166	4	for	for	ADP
dti-2277	166	5	three	three	NUM
dti-2277	166	6	weeks	week	NOUN
dti-2277	166	7	eliminated	eliminate	VERB
dti-2277	166	8	hcv	hcv	PROPN
dti-2277	166	9	rna	rna	NOUN
dti-2277	166	10	from	from	ADP
dti-2277	166	11	host	host	NOUN
dti-2277	166	12	cells	cell	NOUN
dti-2277	166	13	to	to	ADP
dti-2277	166	14	under	under	ADP
dti-2277	166	15	detectable	detectable	ADJ
dti-2277	166	16	level	level	NOUN
dti-2277	166	17	.	.	PUNCT
dti-2277	167	1	because	because	SCONJ
dti-2277	167	2	the	the	DET
dti-2277	167	3	immunosuppression	immunosuppression	NOUN
dti-2277	167	4	in	in	ADP
dti-2277	167	5	patients	patient	NOUN
dti-2277	167	6	during	during	ADP
dti-2277	167	7	a	a	DET
dti-2277	167	8	viral	viral	ADJ
dti-2277	167	9	infection	infection	NOUN
dti-2277	167	10	is	be	AUX
dti-2277	167	11	undesirable	undesirable	ADJ
dti-2277	167	12	,	,	PUNCT
dti-2277	167	13	these	these	DET
dti-2277	167	14	non	non	ADJ
dti-2277	167	15	-	-	ADJ
dti-2277	167	16	immunosuppressive	immunosuppressive	ADJ
dti-2277	167	17	variants	variant	NOUN
dti-2277	167	18	of	of	ADP
dti-2277	167	19	csa	csa	PROPN
dti-2277	167	20	that	that	PRON
dti-2277	167	21	inhibit	inhibit	VERB
dti-2277	167	22	cyp	cyp	ADJ
dti-2277	167	23	activity	activity	NOUN
dti-2277	167	24	are	be	AUX
dti-2277	167	25	likely	likely	ADJ
dti-2277	167	26	to	to	PART
dti-2277	167	27	offer	offer	VERB
dti-2277	167	28	great	great	ADJ
dti-2277	167	29	promise	promise	NOUN
dti-2277	167	30	for	for	ADP
dti-2277	167	31	the	the	DET
dti-2277	167	32	treatment	treatment	NOUN
dti-2277	167	33	of	of	ADP
dti-2277	167	34	patients	patient	NOUN
dti-2277	167	35	with	with	ADP
dti-2277	167	36	chronic	chronic	ADJ
dti-2277	167	37	hcv	hcv	NOUN
dti-2277	167	38	infection	infection	NOUN
dti-2277	167	39	.	.	PUNCT
dti-2277	168	1	conclusion	conclusion	NOUN
dti-2277	168	2	cyps	cyps	PROPN
dti-2277	168	3	are	be	AUX
dti-2277	168	4	cellular	cellular	ADJ
dti-2277	168	5	ppiases	ppiase	NOUN
dti-2277	168	6	that	that	PRON
dti-2277	168	7	catalyze	catalyze	VERB
dti-2277	168	8	conformational	conformational	ADJ
dti-2277	168	9	changes	change	NOUN
dti-2277	168	10	in	in	ADP
dti-2277	168	11	proteins	protein	NOUN
dti-2277	168	12	,	,	PUNCT
dti-2277	168	13	but	but	CCONJ
dti-2277	168	14	the	the	DET
dti-2277	168	15	role(s	role(s	PROPN
dti-2277	168	16	)	)	PUNCT
dti-2277	168	17	and	and	CCONJ
dti-2277	168	18	substrates	substrate	NOUN
dti-2277	168	19	for	for	ADP
dti-2277	168	20	this	this	DET
dti-2277	168	21	protein	protein	NOUN
dti-2277	168	22	family	family	NOUN
dti-2277	168	23	in	in	ADP
dti-2277	168	24	cells	cell	NOUN
dti-2277	168	25	are	be	AUX
dti-2277	168	26	not	not	PART
dti-2277	168	27	well	well	ADV
dti-2277	168	28	-	-	PUNCT
dti-2277	168	29	characterized	characterize	VERB
dti-2277	168	30	.	.	PUNCT
dti-2277	169	1	however	however	ADV
dti-2277	169	2	,	,	PUNCT
dti-2277	169	3	discoveries	discovery	NOUN
dti-2277	169	4	of	of	ADP
dti-2277	169	5	the	the	DET
dti-2277	169	6	signifi	signifi	NOUN
dti-2277	169	7	cance	cance	NOUN
dti-2277	169	8	of	of	ADP
dti-2277	169	9	cyp	cyp	ADJ
dti-2277	169	10	in	in	ADP
dti-2277	169	11	life	life	NOUN
dti-2277	169	12	cycles	cycle	NOUN
dti-2277	169	13	for	for	ADP
dti-2277	169	14	several	several	ADJ
dti-2277	169	15	viruses	virus	NOUN
dti-2277	169	16	make	make	VERB
dti-2277	169	17	this	this	DET
dti-2277	169	18	protein	protein	NOUN
dti-2277	169	19	virologically	virologically	ADV
dti-2277	169	20	notable	notable	ADJ
dti-2277	169	21	and	and	CCONJ
dti-2277	169	22	present	present	ADJ
dti-2277	169	23	novel	novel	NOUN
dti-2277	169	24	therapeutic	therapeutic	ADJ
dti-2277	169	25	anti	anti	ADJ
dti-2277	169	26	-	-	ADJ
dti-2277	169	27	viral	viral	ADJ
dti-2277	169	28	targets	target	NOUN
dti-2277	169	29	.	.	PUNCT
dti-2277	170	1	further	further	ADJ
dti-2277	170	2	analyses	analysis	NOUN
dti-2277	170	3	of	of	ADP
dti-2277	170	4	the	the	DET
dti-2277	170	5	role	role	NOUN
dti-2277	170	6	of	of	ADP
dti-2277	170	7	cyps	cyps	PROPN
dti-2277	170	8	in	in	ADP
dti-2277	170	9	viral	viral	ADJ
dti-2277	170	10	life	life	NOUN
dti-2277	170	11	cycles	cycle	NOUN
dti-2277	170	12	should	should	AUX
dti-2277	170	13	reveal	reveal	VERB
dti-2277	170	14	novel	novel	ADJ
dti-2277	170	15	functions	function	NOUN
dti-2277	170	16	for	for	ADP
dti-2277	170	17	these	these	DET
dti-2277	170	18	proteins	protein	NOUN
dti-2277	170	19	as	as	ADV
dti-2277	170	20	well	well	ADV
dti-2277	170	21	as	as	ADP
dti-2277	170	22	provide	provide	VERB
dti-2277	170	23	mechanistic	mechanistic	ADJ
dti-2277	170	24	insight	insight	NOUN
dti-2277	170	25	into	into	ADP
dti-2277	170	26	possible	possible	ADJ
dti-2277	170	27	therapeutic	therapeutic	ADJ
dti-2277	170	28	targets	target	NOUN
dti-2277	170	29	.	.	PUNCT
dti-2277	171	1	references	reference	NOUN
dti-2277	171	2	allain	allain	PROPN
dti-2277	171	3	,	,	PUNCT
dti-2277	171	4	f.	f.	PROPN
dti-2277	171	5	,	,	PUNCT
dti-2277	171	6	durieux	durieux	PROPN
dti-2277	171	7	,	,	PUNCT
dti-2277	171	8	s.	s.	PROPN
dti-2277	171	9	,	,	PUNCT
dti-2277	171	10	denys	denys	PROPN
dti-2277	171	11	,	,	PUNCT
dti-2277	171	12	a.	a.	NOUN
dti-2277	171	13	,	,	PUNCT
dti-2277	171	14	carpentier	carpentier	NOUN
dti-2277	171	15	,	,	PUNCT
dti-2277	171	16	m.	m.	NOUN
dti-2277	171	17	and	and	CCONJ
dti-2277	171	18	spik	spik	PROPN
dti-2277	171	19	,	,	PUNCT
dti-2277	171	20	g.	g.	PROPN
dti-2277	171	21	1999	1999	NUM
dti-2277	171	22	.	.	PUNCT
dti-2277	172	1	cyclophilin	cyclophilin	PROPN
dti-2277	172	2	b	b	PROPN
dti-2277	172	3	binding	bind	VERB
dti-2277	172	4	to	to	ADP
dti-2277	172	5	platelets	platelet	NOUN
dti-2277	172	6	supports	support	VERB
dti-2277	172	7	calcium	calcium	NOUN
dti-2277	172	8	-	-	PUNCT
dti-2277	172	9	dependent	dependent	ADJ
dti-2277	172	10	adhesion	adhesion	NOUN
dti-2277	172	11	to	to	ADP
dti-2277	172	12	collagen	collagen	PROPN
dti-2277	172	13	.	.	PUNCT
dti-2277	173	1	blood	blood	NOUN
dti-2277	173	2	,	,	PUNCT
dti-2277	173	3	94:976–983	94:976–983	PROPN
dti-2277	173	4	.	.	PUNCT
dti-2277	174	1	allain	allain	PROPN
dti-2277	174	2	,	,	PUNCT
dti-2277	174	3	f.	f.	PROPN
dti-2277	174	4	,	,	PUNCT
dti-2277	174	5	vanpouille	vanpouille	PROPN
dti-2277	174	6	,	,	PUNCT
dti-2277	174	7	c.	c.	PROPN
dti-2277	174	8	,	,	PUNCT
dti-2277	174	9	carpentier	carpentier	NOUN
dti-2277	174	10	,	,	PUNCT
dti-2277	174	11	m.	m.	NOUN
dti-2277	174	12	,	,	PUNCT
dti-2277	174	13	slomianny	slomianny	NOUN
dti-2277	174	14	,	,	PUNCT
dti-2277	174	15	m.	m.	PROPN
dti-2277	174	16	c.	c.	PROPN
dti-2277	174	17	,	,	PUNCT
dti-2277	174	18	durieux	durieux	PROPN
dti-2277	174	19	,	,	PUNCT
dti-2277	174	20	s.	s.	PROPN
dti-2277	174	21	and	and	CCONJ
dti-2277	174	22	spik	spik	PROPN
dti-2277	174	23	,	,	PUNCT
dti-2277	174	24	g.	g.	PROPN
dti-2277	174	25	2002	2002	NUM
dti-2277	174	26	.	.	PUNCT
dti-2277	175	1	interaction	interaction	NOUN
dti-2277	175	2	with	with	ADP
dti-2277	175	3	glycosaminoglycans	glycosaminoglycan	NOUN
dti-2277	175	4	is	be	AUX
dti-2277	175	5	required	require	VERB
dti-2277	175	6	for	for	ADP
dti-2277	175	7	cyclophilin	cyclophilin	PROPN
dti-2277	175	8	b	b	PROPN
dti-2277	175	9	to	to	PART
dti-2277	175	10	trigger	trigger	VERB
dti-2277	175	11	integrin	integrin	NOUN
dti-2277	175	12	-	-	PUNCT
dti-2277	175	13	mediated	mediate	VERB
dti-2277	175	14	adhesion	adhesion	NOUN
dti-2277	175	15	of	of	ADP
dti-2277	175	16	peripheral	peripheral	ADJ
dti-2277	175	17	blood	blood	NOUN
dti-2277	175	18	t	t	NOUN
dti-2277	175	19	lymphocytes	lymphocyte	VERB
dti-2277	175	20	to	to	ADP
dti-2277	175	21	extracellular	extracellular	ADJ
dti-2277	175	22	matrix	matrix	NOUN
dti-2277	175	23	.	.	PUNCT
dti-2277	176	1	proc	proc	NOUN
dti-2277	176	2	.	.	PUNCT
dti-2277	177	1	natl	natl	PROPN
dti-2277	177	2	.	.	PUNCT
dti-2277	178	1	acad	acad	PROPN
dti-2277	178	2	.	.	PUNCT
dti-2277	179	1	sci	sci	PROPN
dti-2277	179	2	.	.	PUNCT
dti-2277	179	3	u.s.a	u.s.a	PROPN
dti-2277	179	4	.	.	PROPN
dti-2277	179	5	,	,	PUNCT
dti-2277	179	6	99:2714–2719	99:2714–2719	NUM
dti-2277	179	7	.	.	PUNCT
dti-2277	180	1	baines	baine	NOUN
dti-2277	180	2	,	,	PUNCT
dti-2277	180	3	c.p	c.p	PROPN
dti-2277	180	4	.	.	PROPN
dti-2277	180	5	,	,	PUNCT
dti-2277	180	6	kaiser	kaiser	PROPN
dti-2277	180	7	,	,	PUNCT
dti-2277	180	8	r.a	r.a	PROPN
dti-2277	180	9	.	.	PROPN
dti-2277	180	10	,	,	PUNCT
dti-2277	180	11	purcell	purcell	PROPN
dti-2277	180	12	,	,	PUNCT
dti-2277	180	13	n.h	n.h	PROPN
dti-2277	180	14	.	.	PROPN
dti-2277	180	15	,	,	PUNCT
dti-2277	180	16	blair	blair	PROPN
dti-2277	180	17	,	,	PUNCT
dti-2277	180	18	n.s	n.s	PROPN
dti-2277	180	19	.	.	PROPN
dti-2277	180	20	,	,	PUNCT
dti-2277	180	21	osinska	osinska	PROPN
dti-2277	180	22	,	,	PUNCT
dti-2277	180	23	h.	h.	PROPN
dti-2277	180	24	,	,	PUNCT
dti-2277	180	25	hambleton	hambleton	PROPN
dti-2277	180	26	,	,	PUNCT
dti-2277	180	27	m.a	m.a	PROPN
dti-2277	180	28	.	.	PROPN
dti-2277	180	29	,	,	PUNCT
dti-2277	180	30	brunskill	brunskill	NOUN
dti-2277	180	31	,	,	PUNCT
dti-2277	180	32	e.w	e.w	PROPN
dti-2277	180	33	.	.	PROPN
dti-2277	180	34	,	,	PUNCT
dti-2277	180	35	sayen	sayen	NOUN
dti-2277	180	36	,	,	PUNCT
dti-2277	180	37	m.r	m.r	PROPN
dti-2277	180	38	.	.	PROPN
dti-2277	180	39	,	,	PUNCT
dti-2277	180	40	gottlieb	gottlieb	PROPN
dti-2277	180	41	,	,	PUNCT
dti-2277	180	42	r.a	r.a	PROPN
dti-2277	180	43	.	.	PROPN
dti-2277	180	44	and	and	CCONJ
dti-2277	180	45	dorn	dorn	PROPN
dti-2277	180	46	,	,	PUNCT
dti-2277	180	47	g.	g.	PROPN
dti-2277	180	48	w.	w.	PROPN
dti-2277	180	49	et	et	PROPN
dti-2277	180	50	al	al	PROPN
dti-2277	180	51	.	.	PROPN
dti-2277	180	52	2005	2005	NUM
dti-2277	180	53	.	.	PUNCT
dti-2277	181	1	loss	loss	NOUN
dti-2277	181	2	of	of	ADP
dti-2277	181	3	cyclophilin	cyclophilin	PROPN
dti-2277	181	4	d	d	PROPN
dti-2277	181	5	reveals	reveal	VERB
dti-2277	181	6	a	a	DET
dti-2277	181	7	critical	critical	ADJ
dti-2277	181	8	role	role	NOUN
dti-2277	181	9	for	for	ADP
dti-2277	181	10	mitochondrial	mitochondrial	ADJ
dti-2277	181	11	permeability	permeability	NOUN
dti-2277	181	12	transition	transition	NOUN
dti-2277	181	13	in	in	ADP
dti-2277	181	14	cell	cell	NOUN
dti-2277	181	15	death	death	NOUN
dti-2277	181	16	.	.	PUNCT
dti-2277	182	1	nature	nature	NOUN
dti-2277	182	2	,	,	PUNCT
dti-2277	182	3	434:658–662	434:658–662	NUM
dti-2277	182	4	.	.	PUNCT
dti-2277	183	1	bergsma	bergsma	PROPN
dti-2277	183	2	,	,	PUNCT
dti-2277	183	3	d.j	d.j	PROPN
dti-2277	183	4	.	.	PROPN
dti-2277	183	5	,	,	PUNCT
dti-2277	183	6	eder	eder	NOUN
dti-2277	183	7	,	,	PUNCT
dti-2277	183	8	c.	c.	NOUN
dti-2277	183	9	,	,	PUNCT
dti-2277	183	10	gross	gross	ADJ
dti-2277	183	11	,	,	PUNCT
dti-2277	183	12	m.	m.	NOUN
dti-2277	183	13	,	,	PUNCT
dti-2277	183	14	kersten	kersten	PROPN
dti-2277	183	15	,	,	PUNCT
dti-2277	183	16	h.	h.	PROPN
dti-2277	183	17	,	,	PUNCT
dti-2277	183	18	sylvester	sylvester	PROPN
dti-2277	183	19	,	,	PUNCT
dti-2277	183	20	d.	d.	PROPN
dti-2277	183	21	,	,	PUNCT
dti-2277	183	22	appelbaum	appelbaum	PROPN
dti-2277	183	23	,	,	PUNCT
dti-2277	183	24	e.	e.	PROPN
dti-2277	183	25	,	,	PUNCT
dti-2277	183	26	cusimano	cusimano	PROPN
dti-2277	183	27	,	,	PUNCT
dti-2277	183	28	d.	d.	PROPN
dti-2277	183	29	,	,	PUNCT
dti-2277	183	30	livi	livi	PROPN
dti-2277	183	31	,	,	PUNCT
dti-2277	183	32	g.p	g.p	PROPN
dti-2277	183	33	.	.	PROPN
dti-2277	183	34	,	,	PUNCT
dti-2277	183	35	mclaughlin	mclaughlin	PROPN
dti-2277	183	36	,	,	PUNCT
dti-2277	183	37	m.m	m.m	PROPN
dti-2277	183	38	.	.	PROPN
dti-2277	183	39	and	and	CCONJ
dti-2277	183	40	kasyan	kasyan	PROPN
dti-2277	183	41	,	,	PUNCT
dti-2277	183	42	k.	k.	PROPN
dti-2277	183	43	et	et	PROPN
dti-2277	183	44	al	al	PROPN
dti-2277	183	45	.	.	PROPN
dti-2277	183	46	1991	1991	NUM
dti-2277	183	47	.	.	PUNCT
dti-2277	184	1	the	the	DET
dti-2277	184	2	cyclophilin	cyclophilin	PROPN
dti-2277	184	3	multigene	multigene	PROPN
dti-2277	184	4	family	family	NOUN
dti-2277	184	5	of	of	ADP
dti-2277	184	6	peptidyl	peptidyl	NOUN
dti-2277	184	7	-	-	PUNCT
dti-2277	184	8	prolyl	prolyl	NOUN
dti-2277	184	9	isomerases	isomerase	NOUN
dti-2277	184	10	.	.	PUNCT
dti-2277	185	1	characterization	characterization	NOUN
dti-2277	185	2	of	of	ADP
dti-2277	185	3	three	three	NUM
dti-2277	185	4	separate	separate	ADJ
dti-2277	185	5	human	human	ADJ
dti-2277	185	6	isoforms	isoform	NOUN
dti-2277	185	7	.	.	PUNCT
dti-2277	186	1	j.	j.	PROPN
dti-2277	186	2	biol	biol	PROPN
dti-2277	186	3	.	.	PUNCT
dti-2277	187	1	chem	chem	PROPN
dti-2277	187	2	.	.	PUNCT
dti-2277	187	3	,	,	PUNCT
dti-2277	187	4	266:23204–23214	266:23204–23214	PROPN
dti-2277	187	5	.	.	PUNCT
dti-2277	188	1	berthoux	berthoux	PROPN
dti-2277	188	2	,	,	PUNCT
dti-2277	188	3	l.	l.	PROPN
dti-2277	188	4	,	,	PUNCT
dti-2277	188	5	sebastian	sebastian	PROPN
dti-2277	188	6	,	,	PUNCT
dti-2277	188	7	s.	s.	PROPN
dti-2277	188	8	,	,	PUNCT
dti-2277	188	9	sokolskaja	sokolskaja	PROPN
dti-2277	188	10	,	,	PUNCT
dti-2277	188	11	e.	e.	PROPN
dti-2277	188	12	and	and	CCONJ
dti-2277	188	13	luban	luban	PROPN
dti-2277	188	14	,	,	PUNCT
dti-2277	188	15	j.	j.	PROPN
dti-2277	188	16	2005	2005	NUM
dti-2277	188	17	.	.	PUNCT
dti-2277	189	1	cyclophilin	cyclophilin	PROPN
dti-2277	189	2	a	a	PRON
dti-2277	189	3	is	be	AUX
dti-2277	189	4	required	require	VERB
dti-2277	189	5	for	for	ADP
dti-2277	189	6	trim5{alpha}-mediated	trim5{alpha}-mediate	VERB
dti-2277	189	7	resistance	resistance	NOUN
dti-2277	189	8	to	to	ADP
dti-2277	189	9	hiv-1	hiv-1	X
dti-2277	189	10	in	in	ADP
dti-2277	189	11	old	old	ADJ
dti-2277	189	12	world	world	NOUN
dti-2277	189	13	monkey	monkey	NOUN
dti-2277	189	14	cells	cell	NOUN
dti-2277	189	15	.	.	PUNCT
dti-2277	190	1	proc	proc	NOUN
dti-2277	190	2	.	.	PUNCT
dti-2277	191	1	natl	natl	PROPN
dti-2277	191	2	.	.	PUNCT
dti-2277	192	1	acad	acad	PROPN
dti-2277	192	2	.	.	PUNCT
dti-2277	193	1	sci	sci	PROPN
dti-2277	193	2	.	.	PUNCT
dti-2277	193	3	u.s.a	u.s.a	PROPN
dti-2277	193	4	.	.	PROPN
dti-2277	193	5	,	,	PUNCT
dti-2277	193	6	102:14849	102:14849	NUM
dti-2277	193	7	–	–	PUNCT
dti-2277	193	8	14853	14853	NUM
dti-2277	193	9	.	.	PUNCT
dti-2277	194	1	bierer	bierer	NOUN
dti-2277	194	2	,	,	PUNCT
dti-2277	194	3	b.e	b.e	PROPN
dti-2277	194	4	.	.	PROPN
dti-2277	194	5	,	,	PUNCT
dti-2277	194	6	somers	somers	PROPN
dti-2277	194	7	,	,	PUNCT
dti-2277	194	8	p.k	p.k	PROPN
dti-2277	194	9	.	.	PROPN
dti-2277	194	10	,	,	PUNCT
dti-2277	194	11	wandless	wandless	NOUN
dti-2277	194	12	,	,	PUNCT
dti-2277	194	13	t.j	t.j	PROPN
dti-2277	194	14	.	.	PROPN
dti-2277	194	15	,	,	PUNCT
dti-2277	194	16	burakoff	burakoff	PROPN
dti-2277	194	17	,	,	PUNCT
dti-2277	194	18	s.j	s.j	PROPN
dti-2277	194	19	.	.	PROPN
dti-2277	194	20	and	and	CCONJ
dti-2277	194	21	schreiber	schreiber	PROPN
dti-2277	194	22	,	,	PUNCT
dti-2277	194	23	s.l	s.l	PROPN
dti-2277	194	24	.	.	PROPN
dti-2277	194	25	1990	1990	NUM
dti-2277	194	26	.	.	PUNCT
dti-2277	195	1	probing	probe	VERB
dti-2277	195	2	immunosuppressant	immunosuppressant	ADJ
dti-2277	195	3	action	action	NOUN
dti-2277	195	4	with	with	ADP
dti-2277	195	5	a	a	DET
dti-2277	195	6	nonnatural	nonnatural	ADJ
dti-2277	195	7	immunophilin	immunophilin	NOUN
dti-2277	195	8	ligand	ligand	NOUN
dti-2277	195	9	.	.	PUNCT
dti-2277	196	1	science	science	NOUN
dti-2277	196	2	,	,	PUNCT
dti-2277	196	3	250:556–559	250:556–559	NUM
dti-2277	196	4	.	.	PUNCT
dti-2277	197	1	bose	bose	PROPN
dti-2277	197	2	,	,	PUNCT
dti-2277	197	3	s.	s.	PROPN
dti-2277	197	4	,	,	PUNCT
dti-2277	197	5	mathur	mathur	PROPN
dti-2277	197	6	,	,	PUNCT
dti-2277	197	7	m.	m.	NOUN
dti-2277	197	8	,	,	PUNCT
dti-2277	197	9	bates	bate	NOUN
dti-2277	197	10	,	,	PUNCT
dti-2277	197	11	p.	p.	PROPN
dti-2277	197	12	,	,	PUNCT
dti-2277	197	13	joshi	joshi	PROPN
dti-2277	197	14	,	,	PUNCT
dti-2277	197	15	n.	n.	PROPN
dti-2277	197	16	and	and	CCONJ
dti-2277	197	17	banerjee	banerjee	PROPN
dti-2277	197	18	,	,	PUNCT
dti-2277	197	19	a.k	a.k	PROPN
dti-2277	197	20	.	.	PROPN
dti-2277	197	21	2003	2003	NUM
dti-2277	197	22	.	.	PUNCT
dti-2277	198	1	requirement	requirement	NOUN
dti-2277	198	2	for	for	ADP
dti-2277	198	3	cyclophilin	cyclophilin	PROPN
dti-2277	198	4	a	a	PRON
dti-2277	198	5	for	for	ADP
dti-2277	198	6	the	the	DET
dti-2277	198	7	replication	replication	NOUN
dti-2277	198	8	of	of	ADP
dti-2277	198	9	vesicular	vesicular	ADJ
dti-2277	198	10	stomatitis	stomatitis	NOUN
dti-2277	198	11	virus	virus	NOUN
dti-2277	198	12	new	new	PROPN
dti-2277	198	13	jersey	jersey	PROPN
dti-2277	198	14	serotype	serotype	PROPN
dti-2277	198	15	.	.	PUNCT
dti-2277	199	1	j.	j.	PROPN
dti-2277	199	2	gen	gen	PROPN
dti-2277	199	3	.	.	PROPN
dti-2277	199	4	virol	virol	PROPN
dti-2277	199	5	.	.	PUNCT
dti-2277	200	1	,	,	PUNCT
dti-2277	200	2	84:1687–1699	84:1687–1699	NUM
dti-2277	200	3	.	.	PUNCT
dti-2277	200	4	braaten	braaten	PROPN
dti-2277	200	5	,	,	PUNCT
dti-2277	200	6	d.	d.	PROPN
dti-2277	200	7	,	,	PUNCT
dti-2277	200	8	franke	franke	PROPN
dti-2277	200	9	,	,	PUNCT
dti-2277	200	10	e.k	e.k	PROPN
dti-2277	200	11	.	.	PROPN
dti-2277	200	12	and	and	CCONJ
dti-2277	200	13	luban	luban	PROPN
dti-2277	200	14	,	,	PUNCT
dti-2277	200	15	j.	j.	PROPN
dti-2277	200	16	1996	1996	NUM
dti-2277	200	17	.	.	PUNCT
dti-2277	201	1	cyclophilin	cyclophilin	PROPN
dti-2277	201	2	a	a	PRON
dti-2277	201	3	is	be	AUX
dti-2277	201	4	required	require	VERB
dti-2277	201	5	for	for	ADP
dti-2277	201	6	an	an	DET
dti-2277	201	7	early	early	ADJ
dti-2277	201	8	step	step	NOUN
dti-2277	201	9	in	in	ADP
dti-2277	201	10	the	the	DET
dti-2277	201	11	life	life	NOUN
dti-2277	201	12	cycle	cycle	NOUN
dti-2277	201	13	of	of	ADP
dti-2277	201	14	human	human	ADJ
dti-2277	201	15	immunodefi	immunodefi	PROPN
dti-2277	201	16	ciency	ciency	NOUN
dti-2277	201	17	virus	virus	NOUN
dti-2277	201	18	type	type	NOUN
dti-2277	201	19	1	1	NUM
dti-2277	201	20	before	before	ADP
dti-2277	201	21	the	the	DET
dti-2277	201	22	initiation	initiation	NOUN
dti-2277	201	23	of	of	ADP
dti-2277	201	24	reverse	reverse	ADJ
dti-2277	201	25	transcription	transcription	NOUN
dti-2277	201	26	.	.	PUNCT
dti-2277	202	1	j.	j.	PROPN
dti-2277	202	2	virol	virol	PROPN
dti-2277	202	3	.	.	PUNCT
dti-2277	202	4	,	,	PUNCT
dti-2277	202	5	70:3551–3560	70:3551–3560	X
dti-2277	202	6	.	.	PUNCT
dti-2277	202	7	braaten	braaten	PROPN
dti-2277	202	8	,	,	PUNCT
dti-2277	202	9	d.	d.	PROPN
dti-2277	202	10	and	and	CCONJ
dti-2277	202	11	luban	luban	PROPN
dti-2277	202	12	,	,	PUNCT
dti-2277	202	13	j.	j.	PROPN
dti-2277	202	14	2001	2001	NUM
dti-2277	202	15	.	.	PUNCT
dti-2277	203	1	cyclophilin	cyclophilin	PROPN
dti-2277	203	2	a	a	DET
dti-2277	203	3	regulates	regulate	VERB
dti-2277	203	4	hiv-1	hiv-1	PART
dti-2277	203	5	infectivity	infectivity	NOUN
dti-2277	203	6	,	,	PUNCT
dti-2277	203	7	as	as	SCONJ
dti-2277	203	8	demonstrated	demonstrate	VERB
dti-2277	203	9	by	by	ADP
dti-2277	203	10	gene	gene	NOUN
dti-2277	203	11	targeting	target	VERB
dti-2277	203	12	in	in	ADP
dti-2277	203	13	human	human	PROPN
dti-2277	203	14	t	t	PROPN
dti-2277	203	15	cells	cell	NOUN
dti-2277	203	16	.	.	PUNCT
dti-2277	204	1	embo	embo	NOUN
dti-2277	204	2	.	.	PUNCT
dti-2277	205	1	j.	j.	PROPN
dti-2277	205	2	,	,	PUNCT
dti-2277	205	3	20	20	NUM
dti-2277	205	4	:	:	SYM
dti-2277	205	5	1300–1309	1300–1309	NUM
dti-2277	205	6	.	.	PUNCT
dti-2277	206	1	bram	bram	PROPN
dti-2277	206	2	,	,	PUNCT
dti-2277	206	3	r.j	r.j	PROPN
dti-2277	206	4	.	.	PROPN
dti-2277	206	5	and	and	CCONJ
dti-2277	206	6	crabtree	crabtree	PROPN
dti-2277	206	7	,	,	PUNCT
dti-2277	206	8	g.r	g.r	PROPN
dti-2277	206	9	.	.	PROPN
dti-2277	206	10	1994	1994	NUM
dti-2277	206	11	.	.	PUNCT
dti-2277	207	1	calcium	calcium	NOUN
dti-2277	207	2	signalling	signal	VERB
dti-2277	207	3	in	in	ADP
dti-2277	207	4	t	t	PROPN
dti-2277	207	5	cells	cell	NOUN
dti-2277	207	6	stimulated	stimulate	VERB
dti-2277	207	7	by	by	ADP
dti-2277	207	8	a	a	DET
dti-2277	207	9	cyclophilin	cyclophilin	PROPN
dti-2277	207	10	b	b	NOUN
dti-2277	207	11	-	-	PUNCT
dti-2277	207	12	binding	bind	VERB
dti-2277	207	13	protein	protein	NOUN
dti-2277	207	14	.	.	PUNCT
dti-2277	208	1	nature	nature	NOUN
dti-2277	208	2	,	,	PUNCT
dti-2277	208	3	371:355–358	371:355–358	NUM
dti-2277	208	4	.	.	PUNCT
dti-2277	209	1	brazin	brazin	PROPN
dti-2277	209	2	,	,	PUNCT
dti-2277	209	3	k.n	k.n	PROPN
dti-2277	209	4	.	.	PROPN
dti-2277	209	5	,	,	PUNCT
dti-2277	209	6	mallis	mallis	PROPN
dti-2277	209	7	,	,	PUNCT
dti-2277	209	8	r.j	r.j	PROPN
dti-2277	209	9	.	.	PROPN
dti-2277	209	10	,	,	PUNCT
dti-2277	209	11	fulton	fulton	PROPN
dti-2277	209	12	,	,	PUNCT
dti-2277	209	13	d.b	d.b	PROPN
dti-2277	209	14	.	.	PROPN
dti-2277	209	15	and	and	CCONJ
dti-2277	209	16	andreotti	andreotti	PROPN
dti-2277	209	17	,	,	PUNCT
dti-2277	209	18	a.h	a.h	PROPN
dti-2277	209	19	.	.	PROPN
dti-2277	209	20	2002	2002	NUM
dti-2277	209	21	.	.	PUNCT
dti-2277	210	1	regulation	regulation	NOUN
dti-2277	210	2	of	of	ADP
dti-2277	210	3	the	the	DET
dti-2277	210	4	tyrosine	tyrosine	NOUN
dti-2277	210	5	kinase	kinase	PROPN
dti-2277	210	6	itk	itk	PROPN
dti-2277	210	7	by	by	ADP
dti-2277	210	8	the	the	DET
dti-2277	210	9	peptidyl	peptidyl	NOUN
dti-2277	210	10	-	-	PUNCT
dti-2277	210	11	prolyl	prolyl	NOUN
dti-2277	210	12	isomerase	isomerase	ADJ
dti-2277	210	13	cyclophilin	cyclophilin	PROPN
dti-2277	210	14	a.	a.	NOUN
dti-2277	210	15	proc	proc	PROPN
dti-2277	210	16	.	.	PUNCT
dti-2277	211	1	natl	natl	PROPN
dti-2277	211	2	.	.	PUNCT
dti-2277	212	1	acad	acad	PROPN
dti-2277	212	2	.	.	PUNCT
dti-2277	213	1	sci	sci	PROPN
dti-2277	213	2	.	.	PUNCT
dti-2277	213	3	u.s.a	u.s.a	PROPN
dti-2277	213	4	.	.	PROPN
dti-2277	213	5	,	,	PUNCT
dti-2277	213	6	99:1899–1904	99:1899–1904	NUM
dti-2277	213	7	.	.	X
dti-2277	214	1	cande	cande	PROPN
dti-2277	214	2	,	,	PUNCT
dti-2277	214	3	c.	c.	PROPN
dti-2277	214	4	,	,	PUNCT
dti-2277	214	5	vahsen	vahsen	NOUN
dti-2277	214	6	,	,	PUNCT
dti-2277	214	7	n.	n.	NOUN
dti-2277	214	8	,	,	PUNCT
dti-2277	214	9	kouranti	kouranti	PROPN
dti-2277	214	10	,	,	PUNCT
dti-2277	214	11	i.	i.	PROPN
dti-2277	214	12	,	,	PUNCT
dti-2277	214	13	schmitt	schmitt	PROPN
dti-2277	214	14	,	,	PUNCT
dti-2277	214	15	e.	e.	PROPN
dti-2277	214	16	,	,	PUNCT
dti-2277	214	17	daugas	daugas	PROPN
dti-2277	214	18	,	,	PUNCT
dti-2277	214	19	e.	e.	PROPN
dti-2277	214	20	,	,	PUNCT
dti-2277	214	21	spahr	spahr	PROPN
dti-2277	214	22	,	,	PUNCT
dti-2277	214	23	c.	c.	NOUN
dti-2277	214	24	,	,	PUNCT
dti-2277	214	25	luban	luban	PROPN
dti-2277	214	26	,	,	PUNCT
dti-2277	214	27	j.	j.	PROPN
dti-2277	214	28	,	,	PUNCT
dti-2277	214	29	kroemer	kroemer	PROPN
dti-2277	214	30	,	,	PUNCT
dti-2277	214	31	r.t	r.t	PROPN
dti-2277	214	32	.	.	PROPN
dti-2277	214	33	,	,	PUNCT
dti-2277	214	34	giordanetto	giordanetto	PROPN
dti-2277	214	35	,	,	PUNCT
dti-2277	214	36	f.	f.	PROPN
dti-2277	214	37	,	,	PUNCT
dti-2277	214	38	garrido	garrido	PROPN
dti-2277	214	39	,	,	PUNCT
dti-2277	214	40	c.	c.	PROPN
dti-2277	214	41	et	et	PROPN
dti-2277	214	42	al	al	PROPN
dti-2277	214	43	.	.	PROPN
dti-2277	214	44	2004	2004	NUM
dti-2277	214	45	.	.	PUNCT
dti-2277	215	1	aif	aif	PROPN
dti-2277	215	2	and	and	CCONJ
dti-2277	215	3	cyclophilin	cyclophilin	PROPN
dti-2277	215	4	a	a	DET
dti-2277	215	5	cooperate	cooperate	NOUN
dti-2277	215	6	in	in	ADP
dti-2277	215	7	apoptosis	apoptosis	NOUN
dti-2277	215	8	-	-	PUNCT
dti-2277	215	9	associated	associate	VERB
dti-2277	215	10	chromatinolysis	chromatinolysis	NOUN
dti-2277	215	11	.	.	PUNCT
dti-2277	216	1	oncogene	oncogene	NOUN
dti-2277	216	2	,	,	PUNCT
dti-2277	216	3	23:1514–1521	23:1514–1521	PROPN
dti-2277	216	4	.	.	PUNCT
dti-2277	216	5	castro	castro	PROPN
dti-2277	216	6	,	,	PUNCT
dti-2277	216	7	a.p	a.p	PROPN
dti-2277	216	8	.	.	PROPN
dti-2277	216	9	,	,	PUNCT
dti-2277	216	10	carvalho	carvalho	PROPN
dti-2277	216	11	,	,	PUNCT
dti-2277	216	12	t.m	t.m	PROPN
dti-2277	216	13	.	.	PROPN
dti-2277	216	14	,	,	PUNCT
dti-2277	216	15	moussatche	moussatche	PROPN
dti-2277	216	16	,	,	PUNCT
dti-2277	216	17	n.	n.	NOUN
dti-2277	216	18	and	and	CCONJ
dti-2277	216	19	damaso	damaso	NOUN
dti-2277	216	20	,	,	PUNCT
dti-2277	216	21	c.r	c.r	PROPN
dti-2277	216	22	.	.	PROPN
dti-2277	216	23	2003	2003	NUM
dti-2277	216	24	.	.	PUNCT
dti-2277	217	1	redistribution	redistribution	NOUN
dti-2277	217	2	of	of	ADP
dti-2277	217	3	cyclophilin	cyclophilin	PROPN
dti-2277	217	4	a	a	DET
dti-2277	217	5	to	to	ADP
dti-2277	217	6	viral	viral	ADJ
dti-2277	217	7	factories	factory	NOUN
dti-2277	217	8	during	during	ADP
dti-2277	217	9	vaccinia	vaccinia	NOUN
dti-2277	217	10	virus	virus	NOUN
dti-2277	217	11	infection	infection	NOUN
dti-2277	217	12	and	and	CCONJ
dti-2277	217	13	its	its	PRON
dti-2277	217	14	incorporation	incorporation	NOUN
dti-2277	217	15	into	into	ADP
dti-2277	217	16	mature	mature	ADJ
dti-2277	217	17	particles	particle	NOUN
dti-2277	217	18	.	.	PUNCT
dti-2277	218	1	j	j	PROPN
dti-2277	218	2	.virol	.virol	NOUN
dti-2277	218	3	.	.	PUNCT
dti-2277	219	1	77:9052	77:9052	X
dti-2277	219	2	–	–	PUNCT
dti-2277	219	3	9068	9068	NUM
dti-2277	219	4	.	.	PUNCT
dti-2277	220	1	chen	chen	PROPN
dti-2277	220	2	,	,	PUNCT
dti-2277	220	3	z.	z.	PROPN
dti-2277	220	4	,	,	PUNCT
dti-2277	220	5	mi	mi	PROPN
dti-2277	220	6	,	,	PUNCT
dti-2277	220	7	l.	l.	PROPN
dti-2277	220	8	,	,	PUNCT
dti-2277	220	9	xu	xu	PROPN
dti-2277	220	10	,	,	PUNCT
dti-2277	220	11	j.	j.	PROPN
dti-2277	220	12	,	,	PUNCT
dti-2277	220	13	yu	yu	PROPN
dti-2277	220	14	,	,	PUNCT
dti-2277	220	15	j.	j.	PROPN
dti-2277	220	16	,	,	PUNCT
dti-2277	220	17	wang	wang	PROPN
dti-2277	220	18	,	,	PUNCT
dti-2277	220	19	x.	x.	PROPN
dti-2277	220	20	,	,	PUNCT
dti-2277	220	21	jiang	jiang	PROPN
dti-2277	220	22	,	,	PUNCT
dti-2277	220	23	j.	j.	PROPN
dti-2277	220	24	,	,	PUNCT
dti-2277	220	25	xing	xing	PROPN
dti-2277	220	26	,	,	PUNCT
dti-2277	220	27	j.	j.	PROPN
dti-2277	220	28	,	,	PUNCT
dti-2277	220	29	shang	shang	PROPN
dti-2277	220	30	,	,	PUNCT
dti-2277	220	31	p.	p.	PROPN
dti-2277	220	32	,	,	PUNCT
dti-2277	220	33	qian	qian	PROPN
dti-2277	220	34	,	,	PUNCT
dti-2277	220	35	a.	a.	PROPN
dti-2277	220	36	and	and	CCONJ
dti-2277	220	37	li	li	PROPN
dti-2277	220	38	,	,	PUNCT
dti-2277	220	39	y.	y.	PROPN
dti-2277	220	40	et	et	PROPN
dti-2277	220	41	al	al	PROPN
dti-2277	220	42	.	.	PROPN
dti-2277	220	43	2005	2005	NUM
dti-2277	220	44	.	.	PUNCT
dti-2277	221	1	function	function	NOUN
dti-2277	221	2	of	of	ADP
dti-2277	221	3	hab18g	hab18g	NOUN
dti-2277	221	4	/	/	SYM
dti-2277	221	5	cd147	cd147	PROPN
dti-2277	221	6	in	in	ADP
dti-2277	221	7	invasion	invasion	NOUN
dti-2277	221	8	of	of	ADP
dti-2277	221	9	host	host	NOUN
dti-2277	221	10	cells	cell	NOUN
dti-2277	221	11	by	by	ADP
dti-2277	221	12	severe	severe	ADJ
dti-2277	221	13	acute	acute	ADJ
dti-2277	221	14	respiratory	respiratory	ADJ
dti-2277	221	15	syndrome	syndrome	NOUN
dti-2277	221	16	coronavirus	coronavirus	NOUN
dti-2277	221	17	.	.	PUNCT
dti-2277	222	1	j.	j.	PROPN
dti-2277	222	2	infect	infect	PROPN
dti-2277	222	3	.	.	PUNCT
dti-2277	223	1	dis	dis	PROPN
dti-2277	223	2	.	.	PROPN
dti-2277	223	3	,	,	PUNCT
dti-2277	223	4	191:755–760	191:755–760	NUM
dti-2277	223	5	.	.	PUNCT
dti-2277	224	1	chen	chen	PROPN
dti-2277	224	2	,	,	PUNCT
dti-2277	224	3	z.j	z.j	PROPN
dti-2277	224	4	.	.	PROPN
dti-2277	224	5	,	,	PUNCT
dti-2277	224	6	vetter	vetter	PROPN
dti-2277	224	7	,	,	PUNCT
dti-2277	224	8	m.	m.	PROPN
dti-2277	224	9	,	,	PUNCT
dti-2277	224	10	chang	chang	PROPN
dti-2277	224	11	,	,	PUNCT
dti-2277	224	12	g.d	g.d	PROPN
dti-2277	224	13	.	.	PROPN
dti-2277	224	14	,	,	PUNCT
dti-2277	224	15	liu	liu	PROPN
dti-2277	224	16	,	,	PUNCT
dti-2277	224	17	s.	s.	PROPN
dti-2277	224	18	,	,	PUNCT
dti-2277	224	19	che	che	PROPN
dti-2277	224	20	,	,	PUNCT
dti-2277	224	21	d.	d.	PROPN
dti-2277	224	22	,	,	PUNCT
dti-2277	224	23	ding	ding	NOUN
dti-2277	224	24	,	,	PUNCT
dti-2277	224	25	y.	y.	PROPN
dti-2277	224	26	,	,	PUNCT
dti-2277	224	27	kim	kim	PROPN
dti-2277	224	28	,	,	PUNCT
dti-2277	224	29	s.s	s.s	PROPN
dti-2277	224	30	.	.	PROPN
dti-2277	224	31	and	and	CCONJ
dti-2277	224	32	chang	chang	PROPN
dti-2277	224	33	,	,	PUNCT
dti-2277	224	34	c.h	c.h	PROPN
dti-2277	224	35	.	.	PROPN
dti-2277	224	36	2004	2004	NUM
dti-2277	224	37	.	.	PUNCT
dti-2277	225	1	cyclophilin	cyclophilin	PROPN
dti-2277	225	2	a	a	DET
dti-2277	225	3	functions	function	NOUN
dti-2277	225	4	as	as	ADP
dti-2277	225	5	an	an	DET
dti-2277	225	6	endogenous	endogenous	ADJ
dti-2277	225	7	inhibitor	inhibitor	NOUN
dti-2277	225	8	for	for	ADP
dti-2277	225	9	membrane	membrane	NOUN
dti-2277	225	10	-	-	PUNCT
dti-2277	225	11	bound	bind	VERB
dti-2277	225	12	guanylate	guanylate	NOUN
dti-2277	225	13	cyclase	cyclase	NOUN
dti-2277	225	14	-	-	PUNCT
dti-2277	225	15	a.	a.	NOUN
dti-2277	225	16	hypertension	hypertension	NOUN
dti-2277	225	17	,	,	PUNCT
dti-2277	225	18	44:963–968	44:963–968	PROPN
dti-2277	225	19	.	.	PUNCT
dti-2277	226	1	clipstone	clipstone	PROPN
dti-2277	226	2	,	,	PUNCT
dti-2277	226	3	n.a	n.a	PROPN
dti-2277	226	4	.	.	PROPN
dti-2277	226	5	and	and	CCONJ
dti-2277	226	6	crabtree	crabtree	PROPN
dti-2277	226	7	,	,	PUNCT
dti-2277	226	8	g.r	g.r	PROPN
dti-2277	226	9	.	.	PROPN
dti-2277	226	10	1992	1992	NUM
dti-2277	226	11	.	.	PUNCT
dti-2277	227	1	identifi	identifi	PROPN
dti-2277	227	2	cation	cation	NOUN
dti-2277	227	3	of	of	ADP
dti-2277	227	4	calcineurin	calcineurin	NOUN
dti-2277	227	5	as	as	ADP
dti-2277	227	6	a	a	DET
dti-2277	227	7	key	key	ADJ
dti-2277	227	8	signalling	signal	VERB
dti-2277	227	9	enzyme	enzyme	NOUN
dti-2277	227	10	in	in	ADP
dti-2277	227	11	t	t	NOUN
dti-2277	227	12	-	-	PUNCT
dti-2277	227	13	lymphocyte	lymphocyte	ADJ
dti-2277	227	14	activation	activation	NOUN
dti-2277	227	15	.	.	PUNCT
dti-2277	228	1	nature	nature	NOUN
dti-2277	228	2	,	,	PUNCT
dti-2277	228	3	357	357	NUM
dti-2277	228	4	:	:	PUNCT
dti-2277	228	5	695–697	695–697	NUM
dti-2277	228	6	.	.	PUNCT
dti-2277	229	1	colgan	colgan	PROPN
dti-2277	229	2	,	,	PUNCT
dti-2277	229	3	j.	j.	PROPN
dti-2277	229	4	,	,	PUNCT
dti-2277	229	5	asmal	asmal	ADJ
dti-2277	229	6	,	,	PUNCT
dti-2277	229	7	m.	m.	NOUN
dti-2277	229	8	,	,	PUNCT
dti-2277	229	9	neagu	neagu	NOUN
dti-2277	229	10	,	,	PUNCT
dti-2277	229	11	m.	m.	NOUN
dti-2277	229	12	,	,	PUNCT
dti-2277	229	13	yu	yu	PROPN
dti-2277	229	14	,	,	PUNCT
dti-2277	229	15	b.	b.	PROPN
dti-2277	229	16	,	,	PUNCT
dti-2277	229	17	schneidkraut	schneidkraut	PROPN
dti-2277	229	18	,	,	PUNCT
dti-2277	229	19	j.	j.	PROPN
dti-2277	229	20	,	,	PUNCT
dti-2277	229	21	lee	lee	PROPN
dti-2277	229	22	,	,	PUNCT
dti-2277	229	23	y.	y.	PROPN
dti-2277	229	24	,	,	PUNCT
dti-2277	229	25	sokolskaja	sokolskaja	PROPN
dti-2277	229	26	,	,	PUNCT
dti-2277	229	27	e.	e.	PROPN
dti-2277	229	28	,	,	PUNCT
dti-2277	229	29	andreotti	andreotti	PROPN
dti-2277	229	30	,	,	PUNCT
dti-2277	229	31	a.	a.	NOUN
dti-2277	229	32	and	and	CCONJ
dti-2277	229	33	luban	luban	PROPN
dti-2277	229	34	,	,	PUNCT
dti-2277	229	35	j.	j.	PROPN
dti-2277	229	36	2004	2004	NUM
dti-2277	229	37	.	.	PUNCT
dti-2277	230	1	cyclophilin	cyclophilin	PROPN
dti-2277	230	2	a	a	DET
dti-2277	230	3	regulates	regulate	VERB
dti-2277	230	4	tcr	tcr	PROPN
dti-2277	230	5	signal	signal	PROPN
dti-2277	230	6	strength	strength	NOUN
dti-2277	230	7	in	in	ADP
dti-2277	230	8	cd4	cd4	PROPN
dti-2277	230	9	+	+	PROPN
dti-2277	230	10	t	t	NOUN
dti-2277	230	11	cells	cell	NOUN
dti-2277	230	12	via	via	ADP
dti-2277	230	13	a	a	DET
dti-2277	230	14	proline	proline	NOUN
dti-2277	230	15	-	-	PUNCT
dti-2277	230	16	directed	direct	VERB
dti-2277	230	17	conformational	conformational	ADJ
dti-2277	230	18	switch	switch	NOUN
dti-2277	230	19	in	in	ADP
dti-2277	230	20	itk	itk	PROPN
dti-2277	230	21	.	.	PUNCT
dti-2277	231	1	immunity	immunity	NOUN
dti-2277	231	2	,	,	PUNCT
dti-2277	231	3	21:189–201	21:189–201	PROPN
dti-2277	231	4	.	.	PUNCT
dti-2277	232	1	colgan	colgan	PROPN
dti-2277	232	2	,	,	PUNCT
dti-2277	232	3	j.	j.	PROPN
dti-2277	232	4	,	,	PUNCT
dti-2277	232	5	asmal	asmal	PROPN
dti-2277	232	6	,	,	PUNCT
dti-2277	232	7	m.	m.	NOUN
dti-2277	232	8	,	,	PUNCT
dti-2277	232	9	yu	yu	PROPN
dti-2277	232	10	,	,	PUNCT
dti-2277	232	11	b.	b.	PROPN
dti-2277	232	12	and	and	CCONJ
dti-2277	232	13	luban	luban	PROPN
dti-2277	232	14	,	,	PUNCT
dti-2277	232	15	j.	j.	PROPN
dti-2277	232	16	2005	2005	NUM
dti-2277	232	17	.	.	PUNCT
dti-2277	233	1	cyclophilin	cyclophilin	PROPN
dti-2277	233	2	a	a	PROPN
dti-2277	233	3	-	-	PUNCT
dti-2277	233	4	defi	defi	NOUN
dti-2277	233	5	cient	cient	NOUN
dti-2277	233	6	mice	mouse	NOUN
dti-2277	233	7	are	be	AUX
dti-2277	233	8	resistant	resistant	ADJ
dti-2277	233	9	to	to	ADP
dti-2277	233	10	immunosuppression	immunosuppression	NOUN
dti-2277	233	11	by	by	ADP
dti-2277	233	12	cyclosporine	cyclosporine	NOUN
dti-2277	233	13	.	.	PUNCT
dti-2277	234	1	j.	j.	PROPN
dti-2277	234	2	immunol	immunol	PROPN
dti-2277	234	3	.	.	PROPN
dti-2277	234	4	,	,	PUNCT
dti-2277	234	5	174:6030–6038	174:6030–6038	PROPN
dti-2277	234	6	.	.	PUNCT
dti-2277	234	7	drug	drug	NOUN
dti-2277	234	8	target	target	NOUN
dti-2277	234	9	insights	insight	NOUN
dti-2277	234	10	2007	2007	NUM
dti-2277	234	11	:	:	PUNCT
dti-2277	234	12	2	2	NUM
dti-2277	234	13	16	16	NUM
dti-2277	234	14	watashi	watashi	NOUN
dti-2277	234	15	and	and	CCONJ
dti-2277	234	16	shimotohno	shimotohno	PROPN
dti-2277	234	17	crompton	crompton	PROPN
dti-2277	234	18	,	,	PUNCT
dti-2277	234	19	m.	m.	NOUN
dti-2277	234	20	,	,	PUNCT
dti-2277	234	21	virji	virji	PROPN
dti-2277	234	22	,	,	PUNCT
dti-2277	234	23	s.	s.	PROPN
dti-2277	234	24	and	and	CCONJ
dti-2277	234	25	ward	ward	PROPN
dti-2277	234	26	,	,	PUNCT
dti-2277	234	27	j.m	j.m	PROPN
dti-2277	234	28	.	.	PROPN
dti-2277	234	29	1998	1998	NUM
dti-2277	234	30	.	.	PUNCT
dti-2277	235	1	cyclophilin	cyclophilin	PROPN
dti-2277	235	2	-	-	PUNCT
dti-2277	235	3	d	d	PROPN
dti-2277	235	4	binds	bind	VERB
dti-2277	235	5	strongly	strongly	ADV
dti-2277	235	6	to	to	ADP
dti-2277	235	7	complexes	complex	NOUN
dti-2277	235	8	of	of	ADP
dti-2277	235	9	the	the	DET
dti-2277	235	10	voltage	voltage	NOUN
dti-2277	235	11	-	-	PUNCT
dti-2277	235	12	dependent	dependent	ADJ
dti-2277	235	13	anion	anion	NOUN
dti-2277	235	14	channel	channel	NOUN
dti-2277	235	15	and	and	CCONJ
dti-2277	235	16	the	the	DET
dti-2277	235	17	adenine	adenine	ADJ
dti-2277	235	18	nucleotide	nucleotide	NOUN
dti-2277	235	19	translocase	translocase	NOUN
dti-2277	235	20	to	to	PART
dti-2277	235	21	form	form	VERB
dti-2277	235	22	the	the	DET
dti-2277	235	23	permeability	permeability	NOUN
dti-2277	235	24	transition	transition	NOUN
dti-2277	235	25	pore	pore	NOUN
dti-2277	235	26	.	.	PUNCT
dti-2277	236	1	eur	eur	PROPN
dti-2277	236	2	.	.	PUNCT
dti-2277	237	1	j.	j.	PROPN
dti-2277	237	2	biochem	biochem	PROPN
dti-2277	237	3	,	,	PUNCT
dti-2277	237	4	258:729–735	258:729–735	NUM
dti-2277	237	5	.	.	PUNCT
dti-2277	238	1	cullen	cullen	PROPN
dti-2277	238	2	,	,	PUNCT
dti-2277	238	3	b.r	b.r	PROPN
dti-2277	238	4	.	.	PROPN
dti-2277	238	5	2003	2003	NUM
dti-2277	238	6	.	.	PUNCT
dti-2277	239	1	hiv-1	hiv-1	X
dti-2277	239	2	infection	infection	NOUN
dti-2277	239	3	:	:	PUNCT
dti-2277	239	4	fooling	fool	VERB
dti-2277	239	5	the	the	DET
dti-2277	239	6	gatekeeper	gatekeeper	NOUN
dti-2277	239	7	.	.	PUNCT
dti-2277	240	1	nat	nat	PROPN
dti-2277	240	2	.	.	PUNCT
dti-2277	241	1	med	med	PROPN
dti-2277	241	2	.	.	PROPN
dti-2277	241	3	,	,	PUNCT
dti-2277	241	4	9	9	NUM
dti-2277	241	5	:	:	SYM
dti-2277	241	6	1112–1113	1112–1113	NUM
dti-2277	241	7	.	.	PUNCT
dti-2277	242	1	damaso	damaso	PROPN
dti-2277	242	2	,	,	PUNCT
dti-2277	242	3	c.r	c.r	PROPN
dti-2277	242	4	.	.	PROPN
dti-2277	242	5	and	and	CCONJ
dti-2277	242	6	moussatche	moussatche	PROPN
dti-2277	242	7	,	,	PUNCT
dti-2277	242	8	n.	n.	NOUN
dti-2277	242	9	1998	1998	NUM
dti-2277	242	10	.	.	PUNCT
dti-2277	243	1	inhibition	inhibition	NOUN
dti-2277	243	2	of	of	ADP
dti-2277	243	3	vaccinia	vaccinia	NOUN
dti-2277	243	4	virus	virus	NOUN
dti-2277	243	5	replication	replication	NOUN
dti-2277	243	6	by	by	ADP
dti-2277	243	7	cyclosporin	cyclosporin	NOUN
dti-2277	243	8	a	a	DET
dti-2277	243	9	analogues	analogue	NOUN
dti-2277	243	10	correlates	correlate	VERB
dti-2277	243	11	with	with	ADP
dti-2277	243	12	their	their	PRON
dti-2277	243	13	affi	affi	ADJ
dti-2277	243	14	nity	nity	NOUN
dti-2277	243	15	for	for	ADP
dti-2277	243	16	cellular	cellular	ADJ
dti-2277	243	17	cyclophilins	cyclophilin	NOUN
dti-2277	243	18	.	.	PUNCT
dti-2277	244	1	j.	j.	PROPN
dti-2277	244	2	gen	gen	PROPN
dti-2277	244	3	.	.	PROPN
dti-2277	244	4	virol	virol	PROPN
dti-2277	244	5	.	.	PUNCT
dti-2277	244	6	,	,	PUNCT
dti-2277	244	7	79	79	NUM
dti-2277	244	8	(	(	PUNCT
dti-2277	244	9	pt	pt	NOUN
dti-2277	244	10	2):339–346	2):339–346	NUM
dti-2277	244	11	.	.	PUNCT
dti-2277	244	12	di	di	NOUN
dti-2277	244	13	bisceglie	bisceglie	PROPN
dti-2277	244	14	,	,	PUNCT
dti-2277	244	15	a.m.	a.m.	ADV
dti-2277	244	16	,	,	PUNCT
dti-2277	244	17	mchutchison	mchutchison	PROPN
dti-2277	244	18	,	,	PUNCT
dti-2277	244	19	j.	j.	PROPN
dti-2277	244	20	and	and	CCONJ
dti-2277	244	21	rice	rice	PROPN
dti-2277	244	22	,	,	PUNCT
dti-2277	244	23	c.m	c.m	PROPN
dti-2277	244	24	.	.	PROPN
dti-2277	244	25	2002	2002	NUM
dti-2277	244	26	.	.	PUNCT
dti-2277	245	1	new	new	ADJ
dti-2277	245	2	therapeutic	therapeutic	ADJ
dti-2277	245	3	strategies	strategy	NOUN
dti-2277	245	4	for	for	ADP
dti-2277	245	5	hepatitis	hepatitis	PROPN
dti-2277	245	6	c.	c.	PROPN
dti-2277	245	7	hepatology	hepatology	NOUN
dti-2277	245	8	35:224–231	35:224–231	PROPN
dti-2277	245	9	.	.	PUNCT
dti-2277	246	1	duina	duina	PROPN
dti-2277	246	2	,	,	PUNCT
dti-2277	246	3	a.a	a.a	PROPN
dti-2277	246	4	.	.	PROPN
dti-2277	246	5	,	,	PUNCT
dti-2277	246	6	chang	chang	PROPN
dti-2277	246	7	,	,	PUNCT
dti-2277	246	8	h.c	h.c	PROPN
dti-2277	246	9	.	.	PROPN
dti-2277	246	10	,	,	PUNCT
dti-2277	246	11	marsh	marsh	PROPN
dti-2277	246	12	,	,	PUNCT
dti-2277	246	13	j.a	j.a	PROPN
dti-2277	246	14	.	.	PROPN
dti-2277	246	15	,	,	PUNCT
dti-2277	246	16	lindquist	lindquist	PROPN
dti-2277	246	17	,	,	PUNCT
dti-2277	246	18	s.	s.	PROPN
dti-2277	246	19	and	and	CCONJ
dti-2277	246	20	gaber	gaber	PROPN
dti-2277	246	21	,	,	PUNCT
dti-2277	246	22	r.	r.	PROPN
dti-2277	246	23	f.	f.	PROPN
dti-2277	246	24	1996	1996	NUM
dti-2277	246	25	.	.	PUNCT
dti-2277	247	1	a	a	DET
dti-2277	247	2	cyclophilin	cyclophilin	PROPN
dti-2277	247	3	function	function	NOUN
dti-2277	247	4	in	in	ADP
dti-2277	247	5	hsp90	hsp90	ADJ
dti-2277	247	6	-	-	PUNCT
dti-2277	247	7	dependent	dependent	ADJ
dti-2277	247	8	signal	signal	NOUN
dti-2277	247	9	transduction	transduction	NOUN
dti-2277	247	10	.	.	PUNCT
dti-2277	248	1	science	science	NOUN
dti-2277	248	2	,	,	PUNCT
dti-2277	248	3	274:1713–1715	274:1713–1715	NUM
dti-2277	248	4	.	.	PUNCT
dti-2277	249	1	endrich	endrich	PROPN
dti-2277	249	2	,	,	PUNCT
dti-2277	249	3	m.m	m.m	PROPN
dti-2277	249	4	.	.	PROPN
dti-2277	249	5	and	and	CCONJ
dti-2277	249	6	gehring	gehring	PROPN
dti-2277	249	7	,	,	PUNCT
dti-2277	249	8	h.	h.	PROPN
dti-2277	249	9	1998	1998	NUM
dti-2277	249	10	.	.	PUNCT
dti-2277	250	1	the	the	DET
dti-2277	250	2	v3	v3	PROPN
dti-2277	250	3	loop	loop	NOUN
dti-2277	250	4	of	of	ADP
dti-2277	250	5	human	human	ADJ
dti-2277	250	6	immunodefi	immunodefi	PROPN
dti-2277	250	7	ciency	ciency	NOUN
dti-2277	250	8	virus	virus	NOUN
dti-2277	250	9	type-1	type-1	PROPN
dti-2277	250	10	envelope	envelope	NOUN
dti-2277	250	11	protein	protein	NOUN
dti-2277	250	12	is	be	AUX
dti-2277	250	13	a	a	DET
dti-2277	250	14	high	high	ADJ
dti-2277	250	15	-	-	PUNCT
dti-2277	250	16	affi	affi	NOUN
dti-2277	250	17	nity	nity	NOUN
dti-2277	250	18	ligand	ligand	NOUN
dti-2277	250	19	for	for	ADP
dti-2277	250	20	immunophilins	immunophilin	NOUN
dti-2277	250	21	present	present	ADJ
dti-2277	250	22	in	in	ADP
dti-2277	250	23	human	human	ADJ
dti-2277	250	24	blood	blood	NOUN
dti-2277	250	25	.	.	PUNCT
dti-2277	251	1	eur	eur	PROPN
dti-2277	251	2	.	.	PUNCT
dti-2277	252	1	j.	j.	PROPN
dti-2277	252	2	biochem	biochem	PROPN
dti-2277	252	3	.	.	PUNCT
dti-2277	252	4	,	,	PUNCT
dti-2277	252	5	252	252	NUM
dti-2277	252	6	:	:	PUNCT
dti-2277	252	7	441–446	441–446	NUM
dti-2277	252	8	.	.	PUNCT
dti-2277	252	9	evans	evans	PROPN
dti-2277	252	10	,	,	PUNCT
dti-2277	252	11	m.j	m.j	PROPN
dti-2277	252	12	.	.	PROPN
dti-2277	252	13	,	,	PUNCT
dti-2277	252	14	rice	rice	PROPN
dti-2277	252	15	,	,	PUNCT
dti-2277	252	16	c.m	c.m	PROPN
dti-2277	252	17	.	.	PROPN
dti-2277	252	18	and	and	CCONJ
dti-2277	252	19	goff	goff	PROPN
dti-2277	252	20	,	,	PUNCT
dti-2277	252	21	s.p	s.p	PROPN
dti-2277	252	22	.	.	PROPN
dti-2277	252	23	2004	2004	NUM
dti-2277	252	24	.	.	PUNCT
dti-2277	253	1	phosphorylation	phosphorylation	NOUN
dti-2277	253	2	of	of	ADP
dti-2277	253	3	hepatitis	hepatitis	PROPN
dti-2277	253	4	c	c	PROPN
dti-2277	253	5	virus	virus	NOUN
dti-2277	253	6	nonstructural	nonstructural	ADJ
dti-2277	253	7	protein	protein	NOUN
dti-2277	253	8	5a	5a	NUM
dti-2277	253	9	modulates	modulate	VERB
dti-2277	253	10	its	its	PRON
dti-2277	253	11	protein	protein	NOUN
dti-2277	253	12	interactions	interaction	NOUN
dti-2277	253	13	and	and	CCONJ
dti-2277	253	14	viral	viral	ADJ
dti-2277	253	15	rna	rna	NOUN
dti-2277	253	16	replication	replication	NOUN
dti-2277	253	17	.	.	PUNCT
dti-2277	254	1	proc	proc	PROPN
dti-2277	254	2	.	.	PUNCT
dti-2277	255	1	natl	natl	PROPN
dti-2277	255	2	.	.	PUNCT
dti-2277	256	1	acad	acad	PROPN
dti-2277	256	2	.	.	PUNCT
dti-2277	257	1	sci	sci	PROPN
dti-2277	257	2	.	.	PUNCT
dti-2277	257	3	u.s.a	u.s.a	PROPN
dti-2277	257	4	.	.	PROPN
dti-2277	257	5	,	,	PUNCT
dti-2277	257	6	101	101	NUM
dti-2277	257	7	:	:	SYM
dti-2277	257	8	13038–13043	13038–13043	NUM
dti-2277	257	9	.	.	PUNCT
dti-2277	258	1	firpi	firpi	PROPN
dti-2277	258	2	,	,	PUNCT
dti-2277	258	3	r.j	r.j	PROPN
dti-2277	258	4	.	.	PROPN
dti-2277	258	5	,	,	PUNCT
dti-2277	258	6	zhu	zhu	PROPN
dti-2277	258	7	,	,	PUNCT
dti-2277	258	8	h.	h.	PROPN
dti-2277	258	9	,	,	PUNCT
dti-2277	258	10	morelli	morelli	PROPN
dti-2277	258	11	,	,	PUNCT
dti-2277	258	12	g.	g.	PROPN
dti-2277	258	13	,	,	PUNCT
dti-2277	258	14	abdelmalek	abdelmalek	PROPN
dti-2277	258	15	,	,	PUNCT
dti-2277	258	16	m.f	m.f	PROPN
dti-2277	258	17	.	.	PROPN
dti-2277	258	18	,	,	PUNCT
dti-2277	258	19	soldevila	soldevila	PROPN
dti-2277	258	20	-	-	PUNCT
dti-2277	258	21	pico	pico	NOUN
dti-2277	258	22	,	,	PUNCT
dti-2277	258	23	c.	c.	PROPN
dti-2277	258	24	,	,	PUNCT
dti-2277	258	25	machicao	machicao	PROPN
dti-2277	258	26	,	,	PUNCT
dti-2277	258	27	v.i	v.i	PROPN
dti-2277	258	28	.	.	PROPN
dti-2277	258	29	,	,	PUNCT
dti-2277	258	30	cabrera	cabrera	PROPN
dti-2277	258	31	,	,	PUNCT
dti-2277	258	32	r.	r.	PROPN
dti-2277	258	33	,	,	PUNCT
dti-2277	258	34	reed	reed	PROPN
dti-2277	258	35	,	,	PUNCT
dti-2277	258	36	a.i	a.i	PROPN
dti-2277	258	37	.	.	PROPN
dti-2277	258	38	,	,	PUNCT
dti-2277	258	39	liu	liu	PROPN
dti-2277	258	40	,	,	PUNCT
dti-2277	258	41	c.	c.	PROPN
dti-2277	258	42	and	and	CCONJ
dti-2277	258	43	nelson	nelson	PROPN
dti-2277	258	44	,	,	PUNCT
dti-2277	258	45	d.r	d.r	PROPN
dti-2277	258	46	.	.	PROPN
dti-2277	258	47	2006	2006	NUM
dti-2277	258	48	.	.	PUNCT
dti-2277	259	1	cyclosporine	cyclosporine	PROPN
dti-2277	259	2	suppresses	suppress	VERB
dti-2277	259	3	hepatitis	hepatitis	PROPN
dti-2277	259	4	c	c	PROPN
dti-2277	259	5	virus	virus	NOUN
dti-2277	259	6	in	in	ADP
dti-2277	259	7	vitro	vitro	X
dti-2277	259	8	and	and	CCONJ
dti-2277	259	9	increases	increase	VERB
dti-2277	259	10	the	the	DET
dti-2277	259	11	chance	chance	NOUN
dti-2277	259	12	of	of	ADP
dti-2277	259	13	a	a	DET
dti-2277	259	14	sustained	sustain	VERB
dti-2277	259	15	virological	virological	ADJ
dti-2277	259	16	response	response	NOUN
dti-2277	259	17	after	after	ADP
dti-2277	259	18	liver	liver	NOUN
dti-2277	259	19	transplantation	transplantation	NOUN
dti-2277	259	20	.	.	PUNCT
dti-2277	260	1	liver	liver	NOUN
dti-2277	260	2	transpl	transpl	NOUN
dti-2277	260	3	.	.	PUNCT
dti-2277	260	4	,	,	PUNCT
dti-2277	261	1	12:51–57	12:51–57	NUM
dti-2277	261	2	.	.	PUNCT
dti-2277	262	1	fischer	fischer	PROPN
dti-2277	262	2	,	,	PUNCT
dti-2277	262	3	g.	g.	PROPN
dti-2277	262	4	,	,	PUNCT
dti-2277	262	5	wittmann	wittmann	PROPN
dti-2277	262	6	-	-	PUNCT
dti-2277	262	7	liebold	liebold	ADJ
dti-2277	262	8	,	,	PUNCT
dti-2277	262	9	b.	b.	PROPN
dti-2277	262	10	,	,	PUNCT
dti-2277	262	11	lang	lang	PROPN
dti-2277	262	12	,	,	PUNCT
dti-2277	262	13	k.	k.	PROPN
dti-2277	262	14	,	,	PUNCT
dti-2277	262	15	kiefhaber	kiefhaber	PROPN
dti-2277	262	16	,	,	PUNCT
dti-2277	262	17	t.	t.	PROPN
dti-2277	262	18	and	and	CCONJ
dti-2277	262	19	schmid	schmid	PROPN
dti-2277	262	20	,	,	PUNCT
dti-2277	262	21	f.	f.	PROPN
dti-2277	262	22	x.	x.	PROPN
dti-2277	262	23	1989	1989	NUM
dti-2277	262	24	.	.	PUNCT
dti-2277	263	1	cyclophilin	cyclophilin	PROPN
dti-2277	263	2	and	and	CCONJ
dti-2277	263	3	peptidyl	peptidyl	NOUN
dti-2277	263	4	-	-	PUNCT
dti-2277	263	5	prolyl	prolyl	NOUN
dti-2277	263	6	cis	cis	NOUN
dti-2277	263	7	-	-	PUNCT
dti-2277	263	8	trans	trans	ADJ
dti-2277	263	9	isomerase	isomerase	NOUN
dti-2277	263	10	are	be	AUX
dti-2277	263	11	probably	probably	ADV
dti-2277	263	12	identical	identical	ADJ
dti-2277	263	13	proteins	protein	NOUN
dti-2277	263	14	.	.	PUNCT
dti-2277	264	1	nature	nature	NOUN
dti-2277	264	2	,	,	PUNCT
dti-2277	264	3	337:476–478	337:476–478	NUM
dti-2277	264	4	.	.	PUNCT
dti-2277	265	1	franke	franke	PROPN
dti-2277	265	2	,	,	PUNCT
dti-2277	265	3	e.	e.	PROPN
dti-2277	265	4	k.	k.	PROPN
dti-2277	265	5	,	,	PUNCT
dti-2277	265	6	yuan	yuan	PROPN
dti-2277	265	7	,	,	PUNCT
dti-2277	265	8	h.	h.	PROPN
dti-2277	265	9	e.	e.	PROPN
dti-2277	265	10	and	and	CCONJ
dti-2277	265	11	luban	luban	PROPN
dti-2277	265	12	,	,	PUNCT
dti-2277	265	13	j.	j.	PROPN
dti-2277	265	14	1994	1994	NUM
dti-2277	265	15	.	.	PUNCT
dti-2277	266	1	specifi	specifi	PROPN
dti-2277	266	2	c	c	PROPN
dti-2277	266	3	incorporation	incorporation	NOUN
dti-2277	266	4	of	of	ADP
dti-2277	266	5	cyclophilin	cyclophilin	PROPN
dti-2277	267	1	a	a	PRON
dti-2277	267	2	into	into	ADP
dti-2277	267	3	hiv-1	hiv-1	ADJ
dti-2277	267	4	virions	virion	NOUN
dti-2277	267	5	.	.	PUNCT
dti-2277	268	1	nature	nature	NOUN
dti-2277	268	2	,	,	PUNCT
dti-2277	268	3	372:359–362	372:359–362	NUM
dti-2277	268	4	.	.	PUNCT
dti-2277	269	1	friedman	friedman	PROPN
dti-2277	269	2	,	,	PUNCT
dti-2277	269	3	j.	j.	PROPN
dti-2277	269	4	and	and	CCONJ
dti-2277	269	5	weissman	weissman	PROPN
dti-2277	269	6	,	,	PUNCT
dti-2277	269	7	i.	i.	PROPN
dti-2277	269	8	1991	1991	NUM
dti-2277	269	9	.	.	PUNCT
dti-2277	270	1	two	two	NUM
dti-2277	270	2	cytoplasmic	cytoplasmic	ADJ
dti-2277	270	3	candidates	candidate	NOUN
dti-2277	270	4	for	for	ADP
dti-2277	270	5	immunophilin	immunophilin	NOUN
dti-2277	270	6	action	action	NOUN
dti-2277	270	7	are	be	AUX
dti-2277	270	8	revealed	reveal	VERB
dti-2277	270	9	by	by	ADP
dti-2277	270	10	affi	affi	PROPN
dti-2277	270	11	nity	nity	NOUN
dti-2277	270	12	for	for	ADP
dti-2277	270	13	a	a	DET
dti-2277	270	14	new	new	ADJ
dti-2277	270	15	cyclophilin	cyclophilin	NOUN
dti-2277	270	16	:	:	PUNCT
dti-2277	270	17	one	one	NUM
dti-2277	270	18	in	in	ADP
dti-2277	270	19	the	the	DET
dti-2277	270	20	presence	presence	NOUN
dti-2277	270	21	and	and	CCONJ
dti-2277	270	22	one	one	NUM
dti-2277	270	23	in	in	ADP
dti-2277	270	24	the	the	DET
dti-2277	270	25	absence	absence	NOUN
dti-2277	270	26	of	of	ADP
dti-2277	270	27	csa	csa	PROPN
dti-2277	270	28	.	.	PROPN
dti-2277	270	29	cell	cell	PROPN
dti-2277	270	30	,	,	PUNCT
dti-2277	270	31	66:799–806	66:799–806	PROPN
dti-2277	270	32	.	.	PUNCT
dti-2277	271	1	fruman	fruman	NOUN
dti-2277	271	2	,	,	PUNCT
dti-2277	271	3	d.a	d.a	PROPN
dti-2277	271	4	.	.	PROPN
dti-2277	271	5	,	,	PUNCT
dti-2277	271	6	klee	klee	PROPN
dti-2277	271	7	,	,	PUNCT
dti-2277	271	8	c.b	c.b	PROPN
dti-2277	271	9	.	.	PROPN
dti-2277	271	10	,	,	PUNCT
dti-2277	271	11	bierer	bierer	PROPN
dti-2277	271	12	,	,	PUNCT
dti-2277	271	13	b.e	b.e	PROPN
dti-2277	271	14	.	.	PROPN
dti-2277	271	15	and	and	CCONJ
dti-2277	271	16	burakoff	burakoff	PROPN
dti-2277	271	17	,	,	PUNCT
dti-2277	271	18	s.j	s.j	PROPN
dti-2277	271	19	.	.	PROPN
dti-2277	271	20	1992	1992	NUM
dti-2277	271	21	.	.	PUNCT
dti-2277	272	1	calcineurin	calcineurin	ADJ
dti-2277	272	2	phosphatase	phosphatase	NOUN
dti-2277	272	3	activity	activity	NOUN
dti-2277	272	4	in	in	ADP
dti-2277	272	5	t	t	PROPN
dti-2277	272	6	lymphocytes	lymphocyte	NOUN
dti-2277	272	7	is	be	AUX
dti-2277	272	8	inhibited	inhibit	VERB
dti-2277	272	9	by	by	ADP
dti-2277	272	10	fk	fk	INTJ
dti-2277	272	11	506	506	NUM
dti-2277	272	12	and	and	CCONJ
dti-2277	272	13	cyclosporin	cyclosporin	NOUN
dti-2277	272	14	a.	a.	PROPN
dti-2277	272	15	proc	proc	PROPN
dti-2277	272	16	.	.	PUNCT
dti-2277	273	1	natl	natl	PROPN
dti-2277	273	2	.	.	PUNCT
dti-2277	274	1	acad	acad	PROPN
dti-2277	274	2	.	.	PUNCT
dti-2277	275	1	sci	sci	PROPN
dti-2277	275	2	.	.	PUNCT
dti-2277	275	3	u.s.a	u.s.a	PROPN
dti-2277	275	4	.	.	PROPN
dti-2277	275	5	,	,	PUNCT
dti-2277	275	6	89:3686–3690	89:3686–3690	NUM
dti-2277	275	7	.	.	PUNCT
dti-2277	276	1	gao	gao	PROPN
dti-2277	276	2	,	,	PUNCT
dti-2277	276	3	l.	l.	PROPN
dti-2277	276	4	,	,	PUNCT
dti-2277	276	5	aizaki	aizaki	PROPN
dti-2277	276	6	,	,	PUNCT
dti-2277	276	7	h.	h.	PROPN
dti-2277	276	8	,	,	PUNCT
dti-2277	276	9	he	he	PRON
dti-2277	276	10	,	,	PUNCT
dti-2277	276	11	j.	j.	PROPN
dti-2277	276	12	w.	w.	PROPN
dti-2277	276	13	and	and	CCONJ
dti-2277	276	14	lai	lai	PROPN
dti-2277	276	15	,	,	PUNCT
dti-2277	276	16	m.m	m.m	PROPN
dti-2277	276	17	.	.	PROPN
dti-2277	276	18	2004	2004	NUM
dti-2277	276	19	.	.	PUNCT
dti-2277	277	1	interactions	interaction	NOUN
dti-2277	277	2	between	between	ADP
dti-2277	277	3	viral	viral	ADJ
dti-2277	277	4	nonstructural	nonstructural	ADJ
dti-2277	277	5	proteins	protein	NOUN
dti-2277	277	6	and	and	CCONJ
dti-2277	277	7	host	host	NOUN
dti-2277	277	8	protein	protein	NOUN
dti-2277	277	9	hvap-33	hvap-33	PROPN
dti-2277	277	10	mediate	mediate	VERB
dti-2277	277	11	the	the	DET
dti-2277	277	12	formation	formation	NOUN
dti-2277	277	13	of	of	ADP
dti-2277	277	14	hepatitis	hepatitis	PROPN
dti-2277	277	15	c	c	PROPN
dti-2277	277	16	virus	virus	NOUN
dti-2277	277	17	rna	rna	NOUN
dti-2277	277	18	replication	replication	NOUN
dti-2277	277	19	complex	complex	NOUN
dti-2277	277	20	on	on	ADP
dti-2277	277	21	lipid	lipid	NOUN
dti-2277	277	22	raft	raft	NOUN
dti-2277	277	23	.	.	PUNCT
dti-2277	278	1	j.	j.	PROPN
dti-2277	278	2	virol	virol	PROPN
dti-2277	278	3	.	.	PUNCT
dti-2277	278	4	,	,	PUNCT
dti-2277	279	1	78:3480–3488	78:3480–3488	X
dti-2277	279	2	.	.	PUNCT
dti-2277	280	1	goto	goto	NOUN
dti-2277	280	2	,	,	PUNCT
dti-2277	280	3	k.	k.	PROPN
dti-2277	280	4	,	,	PUNCT
dti-2277	280	5	watashi	watashi	PROPN
dti-2277	280	6	,	,	PUNCT
dti-2277	280	7	k.	k.	PROPN
dti-2277	280	8	,	,	PUNCT
dti-2277	280	9	murata	murata	PROPN
dti-2277	280	10	,	,	PUNCT
dti-2277	280	11	t.	t.	PROPN
dti-2277	280	12	,	,	PUNCT
dti-2277	280	13	hishiki	hishiki	PROPN
dti-2277	280	14	,	,	PUNCT
dti-2277	280	15	t.	t.	PROPN
dti-2277	280	16	,	,	PUNCT
dti-2277	280	17	hijikata	hijikata	PROPN
dti-2277	280	18	,	,	PUNCT
dti-2277	280	19	m.	m.	NOUN
dti-2277	280	20	and	and	CCONJ
dti-2277	280	21	shimotohno	shimotohno	NOUN
dti-2277	280	22	,	,	PUNCT
dti-2277	280	23	k.	k.	PROPN
dti-2277	280	24	2006	2006	NUM
dti-2277	280	25	.	.	PUNCT
dti-2277	281	1	evaluation	evaluation	NOUN
dti-2277	281	2	of	of	ADP
dti-2277	281	3	the	the	DET
dti-2277	281	4	anti	anti	ADJ
dti-2277	281	5	-	-	ADJ
dti-2277	281	6	hepatitis	hepatitis	ADJ
dti-2277	281	7	c	c	NOUN
dti-2277	281	8	virus	virus	NOUN
dti-2277	281	9	effects	effect	NOUN
dti-2277	281	10	of	of	ADP
dti-2277	281	11	cyclophilin	cyclophilin	PROPN
dti-2277	281	12	inhibitors	inhibitor	NOUN
dti-2277	281	13	,	,	PUNCT
dti-2277	281	14	cyclosporin	cyclosporin	NOUN
dti-2277	281	15	a	a	PRON
dti-2277	281	16	and	and	CCONJ
dti-2277	281	17	nim811	nim811	PROPN
dti-2277	281	18	.	.	PUNCT
dti-2277	282	1	biochem	biochem	PROPN
dti-2277	282	2	.	.	PUNCT
dti-2277	283	1	biophys	biophy	NOUN
dti-2277	283	2	.	.	PUNCT
dti-2277	284	1	res	re	NOUN
dti-2277	284	2	.	.	PUNCT
dti-2277	285	1	commun	commun	PROPN
dti-2277	285	2	.	.	PROPN
dti-2277	285	3	,	,	PUNCT
dti-2277	285	4	343:879–884	343:879–884	NUM
dti-2277	285	5	.	.	PUNCT
dti-2277	286	1	halestrap	halestrap	PROPN
dti-2277	286	2	,	,	PUNCT
dti-2277	286	3	a.p	a.p	PROPN
dti-2277	286	4	.	.	PROPN
dti-2277	286	5	1999	1999	NUM
dti-2277	286	6	.	.	PUNCT
dti-2277	287	1	the	the	DET
dti-2277	287	2	mitochondrial	mitochondrial	ADJ
dti-2277	287	3	permeability	permeability	NOUN
dti-2277	287	4	transition	transition	NOUN
dti-2277	287	5	:	:	PUNCT
dti-2277	287	6	its	its	PRON
dti-2277	287	7	molecular	molecular	ADJ
dti-2277	287	8	mechanism	mechanism	NOUN
dti-2277	287	9	and	and	CCONJ
dti-2277	287	10	role	role	NOUN
dti-2277	287	11	in	in	ADP
dti-2277	287	12	reperfusion	reperfusion	NOUN
dti-2277	287	13	injury	injury	NOUN
dti-2277	287	14	.	.	PUNCT
dti-2277	288	1	biochem	biochem	PROPN
dti-2277	288	2	.	.	PUNCT
dti-2277	289	1	soc	soc	PROPN
dti-2277	289	2	.	.	PUNCT
dti-2277	290	1	symp	symp	PROPN
dti-2277	290	2	.	.	PUNCT
dti-2277	290	3	,	,	PUNCT
dti-2277	291	1	66:181–203	66:181–203	PROPN
dti-2277	291	2	.	.	PUNCT
dti-2277	292	1	handschumacher	handschumacher	PROPN
dti-2277	292	2	,	,	PUNCT
dti-2277	292	3	r.e	r.e	PROPN
dti-2277	292	4	.	.	PROPN
dti-2277	292	5	,	,	PUNCT
dti-2277	292	6	harding	harding	PROPN
dti-2277	292	7	,	,	PUNCT
dti-2277	292	8	m.w	m.w	PROPN
dti-2277	292	9	.	.	PROPN
dti-2277	292	10	,	,	PUNCT
dti-2277	292	11	rice	rice	PROPN
dti-2277	292	12	,	,	PUNCT
dti-2277	292	13	j.	j.	PROPN
dti-2277	292	14	,	,	PUNCT
dti-2277	292	15	drugge	drugge	PROPN
dti-2277	292	16	,	,	PUNCT
dti-2277	292	17	r.j	r.j	PROPN
dti-2277	292	18	.	.	PROPN
dti-2277	292	19	and	and	CCONJ
dti-2277	292	20	speicher	speicher	NOUN
dti-2277	292	21	,	,	PUNCT
dti-2277	292	22	d.w	d.w	PROPN
dti-2277	292	23	.	.	NOUN
dti-2277	292	24	1984	1984	NUM
dti-2277	292	25	.	.	PUNCT
dti-2277	293	1	cyclophilin	cyclophilin	PROPN
dti-2277	293	2	:	:	PUNCT
dti-2277	293	3	a	a	DET
dti-2277	293	4	specifi	specifi	PROPN
dti-2277	293	5	c	c	PROPN
dti-2277	293	6	cytosolic	cytosolic	ADJ
dti-2277	293	7	binding	bind	VERB
dti-2277	293	8	protein	protein	NOUN
dti-2277	293	9	for	for	ADP
dti-2277	293	10	cyclosporin	cyclosporin	NOUN
dti-2277	293	11	a.	a.	NOUN
dti-2277	293	12	science	science	PROPN
dti-2277	293	13	,	,	PUNCT
dti-2277	293	14	226:544–547	226:544–547	NUM
dti-2277	293	15	.	.	PUNCT
dti-2277	294	1	harding	harding	PROPN
dti-2277	294	2	,	,	PUNCT
dti-2277	294	3	m.w	m.w	PROPN
dti-2277	294	4	.	.	PROPN
dti-2277	294	5	,	,	PUNCT
dti-2277	294	6	galat	galat	PROPN
dti-2277	294	7	,	,	PUNCT
dti-2277	294	8	a.	a.	NOUN
dti-2277	294	9	,	,	PUNCT
dti-2277	294	10	uehling	uehling	NOUN
dti-2277	294	11	,	,	PUNCT
dti-2277	294	12	d.e	d.e	PROPN
dti-2277	294	13	.	.	PROPN
dti-2277	294	14	and	and	CCONJ
dti-2277	294	15	schreiber	schreiber	PROPN
dti-2277	294	16	,	,	PUNCT
dti-2277	294	17	s.l	s.l	PROPN
dti-2277	294	18	.	.	PROPN
dti-2277	294	19	1989	1989	NUM
dti-2277	294	20	.	.	PUNCT
dti-2277	295	1	a	a	DET
dti-2277	295	2	receptor	receptor	NOUN
dti-2277	295	3	for	for	ADP
dti-2277	295	4	the	the	DET
dti-2277	295	5	immunosuppressant	immunosuppressant	ADJ
dti-2277	295	6	fk506	fk506	PROPN
dti-2277	295	7	is	be	AUX
dti-2277	295	8	a	a	DET
dti-2277	295	9	cis	cis	NOUN
dti-2277	295	10	-	-	PUNCT
dti-2277	295	11	trans	trans	ADJ
dti-2277	295	12	peptidyl	peptidyl	NOUN
dti-2277	295	13	-	-	PUNCT
dti-2277	295	14	prolyl	prolyl	NOUN
dti-2277	295	15	isomerase	isomerase	NOUN
dti-2277	295	16	.	.	PUNCT
dti-2277	296	1	nature	nature	NOUN
dti-2277	296	2	,	,	PUNCT
dti-2277	296	3	341:758–760	341:758–760	NUM
dti-2277	296	4	.	.	PUNCT
dti-2277	297	1	hatziioannou	hatziioannou	NOUN
dti-2277	297	2	,	,	PUNCT
dti-2277	297	3	t.	t.	PROPN
dti-2277	297	4	,	,	PUNCT
dti-2277	297	5	perez	perez	PROPN
dti-2277	297	6	-	-	PUNCT
dti-2277	297	7	caballero	caballero	PROPN
dti-2277	297	8	,	,	PUNCT
dti-2277	297	9	d.	d.	PROPN
dti-2277	297	10	,	,	PUNCT
dti-2277	297	11	cowan	cowan	PROPN
dti-2277	297	12	,	,	PUNCT
dti-2277	297	13	s.	s.	PROPN
dti-2277	297	14	and	and	CCONJ
dti-2277	297	15	bieniasz	bieniasz	PROPN
dti-2277	297	16	,	,	PUNCT
dti-2277	297	17	p.d	p.d	PROPN
dti-2277	297	18	.	.	PROPN
dti-2277	297	19	2005	2005	NUM
dti-2277	297	20	.	.	PUNCT
dti-2277	298	1	cyclophilin	cyclophilin	PROPN
dti-2277	298	2	interactions	interaction	NOUN
dti-2277	298	3	with	with	ADP
dti-2277	298	4	incoming	incoming	ADJ
dti-2277	298	5	human	human	ADJ
dti-2277	298	6	immunodefi	immunodefi	PROPN
dti-2277	298	7	ciency	ciency	NOUN
dti-2277	298	8	virus	virus	NOUN
dti-2277	298	9	type	type	NOUN
dti-2277	298	10	1	1	NUM
dti-2277	298	11	capsids	capsid	NOUN
dti-2277	298	12	with	with	ADP
dti-2277	298	13	opposing	oppose	VERB
dti-2277	298	14	effects	effect	NOUN
dti-2277	298	15	on	on	ADP
dti-2277	298	16	infectivity	infectivity	NOUN
dti-2277	298	17	in	in	ADP
dti-2277	298	18	human	human	ADJ
dti-2277	298	19	cells	cell	NOUN
dti-2277	298	20	.	.	PUNCT
dti-2277	299	1	j.	j.	PROPN
dti-2277	299	2	virol	virol	PROPN
dti-2277	299	3	,	,	PUNCT
dti-2277	299	4	79:176–183	79:176–183	PROPN
dti-2277	299	5	.	.	PUNCT
dti-2277	300	1	holloway	holloway	PROPN
dti-2277	300	2	,	,	PUNCT
dti-2277	300	3	m.p	m.p	PROPN
dti-2277	300	4	.	.	PROPN
dti-2277	300	5	and	and	CCONJ
dti-2277	300	6	bram	bram	PROPN
dti-2277	300	7	,	,	PUNCT
dti-2277	300	8	r.j	r.j	PROPN
dti-2277	300	9	.	.	PROPN
dti-2277	300	10	1998	1998	NUM
dti-2277	300	11	.	.	PUNCT
dti-2277	301	1	co	co	NOUN
dti-2277	301	2	-	-	NOUN
dti-2277	301	3	localization	localization	NOUN
dti-2277	301	4	of	of	ADP
dti-2277	301	5	calcium	calcium	NOUN
dti-2277	301	6	-	-	PUNCT
dti-2277	301	7	modulating	modulate	VERB
dti-2277	301	8	cyclophilin	cyclophilin	PROPN
dti-2277	301	9	ligand	ligand	NOUN
dti-2277	301	10	with	with	ADP
dti-2277	301	11	intracellular	intracellular	ADJ
dti-2277	301	12	calcium	calcium	NOUN
dti-2277	301	13	pools	pool	NOUN
dti-2277	301	14	.	.	PUNCT
dti-2277	302	1	j.	j.	PROPN
dti-2277	302	2	biol	biol	PROPN
dti-2277	302	3	.	.	PUNCT
dti-2277	303	1	chem	chem	PROPN
dti-2277	303	2	,	,	PUNCT
dti-2277	303	3	273:16346–16350	273:16346–16350	NUM
dti-2277	303	4	.	.	PUNCT
dti-2277	304	1	horowitz	horowitz	PROPN
dti-2277	304	2	,	,	PUNCT
dti-2277	304	3	d.s	d.s	PROPN
dti-2277	304	4	.	.	PROPN
dti-2277	304	5	,	,	PUNCT
dti-2277	304	6	kobayashi	kobayashi	PROPN
dti-2277	304	7	,	,	PUNCT
dti-2277	304	8	r.	r.	PROPN
dti-2277	304	9	and	and	CCONJ
dti-2277	304	10	krainer	krainer	NOUN
dti-2277	304	11	,	,	PUNCT
dti-2277	304	12	a.r	a.r	PROPN
dti-2277	304	13	.	.	PROPN
dti-2277	304	14	1997	1997	NUM
dti-2277	304	15	.	.	PUNCT
dti-2277	305	1	a	a	DET
dti-2277	305	2	new	new	ADJ
dti-2277	305	3	cyclophilin	cyclophilin	NOUN
dti-2277	305	4	and	and	CCONJ
dti-2277	305	5	the	the	DET
dti-2277	305	6	human	human	ADJ
dti-2277	305	7	homologues	homologue	NOUN
dti-2277	305	8	of	of	ADP
dti-2277	305	9	yeast	yeast	NOUN
dti-2277	305	10	prp3	prp3	NOUN
dti-2277	305	11	and	and	CCONJ
dti-2277	305	12	prp4	prp4	PROPN
dti-2277	305	13	form	form	VERB
dti-2277	305	14	a	a	DET
dti-2277	305	15	complex	complex	NOUN
dti-2277	305	16	associated	associate	VERB
dti-2277	305	17	with	with	ADP
dti-2277	305	18	u4	u4	PROPN
dti-2277	305	19	/	/	SYM
dti-2277	305	20	u6	u6	PROPN
dti-2277	305	21	snrnps	snrnps	NOUN
dti-2277	305	22	.	.	PUNCT
dti-2277	306	1	rna	rna	PROPN
dti-2277	306	2	,	,	PUNCT
dti-2277	306	3	3:1374–1387	3:1374–1387	NUM
dti-2277	306	4	.	.	PUNCT
dti-2277	306	5	ishii	ishii	PROPN
dti-2277	306	6	,	,	PUNCT
dti-2277	306	7	n.	n.	NOUN
dti-2277	306	8	,	,	PUNCT
dti-2277	306	9	watashi	watashi	NOUN
dti-2277	306	10	,	,	PUNCT
dti-2277	306	11	k.	k.	PROPN
dti-2277	306	12	,	,	PUNCT
dti-2277	306	13	hishiki	hishiki	PROPN
dti-2277	306	14	,	,	PUNCT
dti-2277	306	15	t.	t.	PROPN
dti-2277	306	16	,	,	PUNCT
dti-2277	306	17	goto	goto	NOUN
dti-2277	306	18	,	,	PUNCT
dti-2277	306	19	k.	k.	PROPN
dti-2277	306	20	,	,	PUNCT
dti-2277	306	21	inoue	inoue	PROPN
dti-2277	306	22	,	,	PUNCT
dti-2277	306	23	d.	d.	PROPN
dti-2277	306	24	,	,	PUNCT
dti-2277	306	25	hijikata	hijikata	PROPN
dti-2277	306	26	,	,	PUNCT
dti-2277	306	27	m.	m.	NOUN
dti-2277	306	28	,	,	PUNCT
dti-2277	306	29	wakita	wakita	PROPN
dti-2277	306	30	,	,	PUNCT
dti-2277	306	31	t.	t.	PROPN
dti-2277	306	32	,	,	PUNCT
dti-2277	306	33	kato	kato	PROPN
dti-2277	306	34	,	,	PUNCT
dti-2277	306	35	n.	n.	NOUN
dti-2277	306	36	,	,	PUNCT
dti-2277	306	37	and	and	CCONJ
dti-2277	306	38	shimotohno	shimotohno	NOUN
dti-2277	306	39	,	,	PUNCT
dti-2277	306	40	k.	k.	PROPN
dti-2277	306	41	2006	2006	NUM
dti-2277	306	42	.	.	PUNCT
dti-2277	307	1	diverse	diverse	ADJ
dti-2277	307	2	effects	effect	NOUN
dti-2277	307	3	of	of	ADP
dti-2277	307	4	cyclosporine	cyclosporine	NOUN
dti-2277	307	5	on	on	ADP
dti-2277	307	6	hepatitis	hepatitis	PROPN
dti-2277	307	7	c	c	PROPN
dti-2277	307	8	virus	virus	NOUN
dti-2277	307	9	strain	strain	NOUN
dti-2277	307	10	replication	replication	NOUN
dti-2277	307	11	.	.	PUNCT
dti-2277	308	1	j.	j.	PROPN
dti-2277	308	2	virol	virol	PROPN
dti-2277	308	3	.	.	PUNCT
dti-2277	308	4	,	,	PUNCT
dti-2277	308	5	80:4510–4520	80:4510–4520	PROPN
dti-2277	308	6	.	.	PUNCT
dti-2277	309	1	jang	jang	PROPN
dti-2277	309	2	,	,	PUNCT
dti-2277	309	3	l.k	l.k	PROPN
dti-2277	309	4	.	.	PROPN
dti-2277	309	5	,	,	PUNCT
dti-2277	309	6	lee	lee	PROPN
dti-2277	309	7	,	,	PUNCT
dti-2277	309	8	z.	z.	PROPN
dti-2277	309	9	h.	h.	PROPN
dti-2277	309	10	,	,	PUNCT
dti-2277	309	11	kim	kim	PROPN
dti-2277	309	12	,	,	PUNCT
dti-2277	309	13	h.h	h.h	PROPN
dti-2277	309	14	.	.	PROPN
dti-2277	309	15	,	,	PUNCT
dti-2277	309	16	hill	hill	PROPN
dti-2277	309	17	,	,	PUNCT
dti-2277	309	18	j.m	j.m	PROPN
dti-2277	309	19	.	.	PROPN
dti-2277	309	20	,	,	PUNCT
dti-2277	309	21	kim	kim	PROPN
dti-2277	309	22	,	,	PUNCT
dti-2277	309	23	j.d	j.d	PROPN
dti-2277	309	24	.	.	PROPN
dti-2277	309	25	and	and	CCONJ
dti-2277	309	26	kwon	kwon	PROPN
dti-2277	309	27	,	,	PUNCT
dti-2277	309	28	b.s	b.s	PROPN
dti-2277	309	29	.	.	PROPN
dti-2277	309	30	2001	2001	NUM
dti-2277	309	31	.	.	PUNCT
dti-2277	310	1	a	a	DET
dti-2277	310	2	novel	novel	ADJ
dti-2277	310	3	leucine	leucine	NOUN
dti-2277	310	4	-	-	PUNCT
dti-2277	310	5	rich	rich	ADJ
dti-2277	310	6	repeat	repeat	NOUN
dti-2277	310	7	protein	protein	NOUN
dti-2277	310	8	(	(	PUNCT
dti-2277	310	9	lrr-1	lrr-1	NUM
dti-2277	310	10	):	):	PUNCT
dti-2277	310	11	potential	potential	ADJ
dti-2277	310	12	involvement	involvement	NOUN
dti-2277	310	13	in	in	ADP
dti-2277	310	14	4	4	NUM
dti-2277	310	15	-	-	PUNCT
dti-2277	310	16	1bb	1bb	ADV
dti-2277	310	17	-	-	PUNCT
dti-2277	310	18	mediated	mediate	VERB
dti-2277	310	19	signal	signal	NOUN
dti-2277	310	20	transduction	transduction	NOUN
dti-2277	310	21	.	.	PUNCT
dti-2277	311	1	mol	mol	NOUN
dti-2277	311	2	.	.	PUNCT
dti-2277	312	1	cells	cell	NOUN
dti-2277	312	2	.	.	PUNCT
dti-2277	313	1	,	,	PUNCT
dti-2277	313	2	12:304	12:304	NUM
dti-2277	313	3	–	–	PUNCT
dti-2277	313	4	312	312	NUM
dti-2277	313	5	.	.	PUNCT
dti-2277	314	1	jin	jin	NOUN
dti-2277	314	2	,	,	PUNCT
dti-2277	314	3	z.g	z.g	PROPN
dti-2277	314	4	.	.	PROPN
dti-2277	314	5	,	,	PUNCT
dti-2277	314	6	melaragno	melaragno	NOUN
dti-2277	314	7	,	,	PUNCT
dti-2277	314	8	m.g	m.g	PROPN
dti-2277	314	9	.	.	PROPN
dti-2277	314	10	,	,	PUNCT
dti-2277	314	11	liao	liao	PROPN
dti-2277	314	12	,	,	PUNCT
dti-2277	314	13	d.f	d.f	PROPN
dti-2277	314	14	.	.	PROPN
dti-2277	314	15	,	,	PUNCT
dti-2277	314	16	yan	yan	PROPN
dti-2277	314	17	,	,	PUNCT
dti-2277	314	18	c.	c.	PROPN
dti-2277	314	19	,	,	PUNCT
dti-2277	314	20	haendeler	haendeler	PROPN
dti-2277	314	21	,	,	PUNCT
dti-2277	314	22	j.	j.	PROPN
dti-2277	314	23	,	,	PUNCT
dti-2277	314	24	suh	suh	PROPN
dti-2277	314	25	,	,	PUNCT
dti-2277	314	26	y.a	y.a	PROPN
dti-2277	314	27	.	.	PROPN
dti-2277	314	28	,	,	PUNCT
dti-2277	314	29	lambeth	lambeth	PROPN
dti-2277	314	30	,	,	PUNCT
dti-2277	314	31	j.d	j.d	PROPN
dti-2277	314	32	.	.	PROPN
dti-2277	314	33	and	and	CCONJ
dti-2277	314	34	berk	berk	PROPN
dti-2277	314	35	,	,	PUNCT
dti-2277	314	36	b.c	b.c	PROPN
dti-2277	314	37	.	.	PROPN
dti-2277	314	38	2000	2000	NUM
dti-2277	314	39	.	.	PUNCT
dti-2277	315	1	cyclophilin	cyclophilin	PROPN
dti-2277	315	2	a	a	PRON
dti-2277	315	3	is	be	AUX
dti-2277	315	4	a	a	DET
dti-2277	315	5	secreted	secrete	VERB
dti-2277	315	6	growth	growth	NOUN
dti-2277	315	7	factor	factor	NOUN
dti-2277	315	8	induced	induce	VERB
dti-2277	315	9	by	by	ADP
dti-2277	315	10	oxidative	oxidative	ADJ
dti-2277	315	11	stress	stress	NOUN
dti-2277	315	12	.	.	PUNCT
dti-2277	316	1	circ	circ	NOUN
dti-2277	316	2	.	.	PUNCT
dti-2277	317	1	res	re	NOUN
dti-2277	317	2	.	.	PROPN
dti-2277	317	3	,	,	PUNCT
dti-2277	317	4	87:789–796	87:789–796	PROPN
dti-2277	317	5	.	.	PUNCT
dti-2277	318	1	kieffer	kieffer	PROPN
dti-2277	318	2	,	,	PUNCT
dti-2277	318	3	l.j	l.j	PROPN
dti-2277	318	4	.	.	PROPN
dti-2277	318	5	,	,	PUNCT
dti-2277	318	6	thalhammer	thalhammer	NOUN
dti-2277	318	7	,	,	PUNCT
dti-2277	318	8	t.	t.	PROPN
dti-2277	318	9	and	and	CCONJ
dti-2277	318	10	handschumacher	handschumacher	PROPN
dti-2277	318	11	,	,	PUNCT
dti-2277	318	12	r.e	r.e	PROPN
dti-2277	318	13	.	.	PROPN
dti-2277	318	14	1992	1992	NUM
dti-2277	318	15	.	.	PUNCT
dti-2277	319	1	isolation	isolation	NOUN
dti-2277	319	2	and	and	CCONJ
dti-2277	319	3	characterization	characterization	NOUN
dti-2277	319	4	of	of	ADP
dti-2277	319	5	a	a	DET
dti-2277	319	6	40	40	NUM
dti-2277	319	7	-	-	PUNCT
dti-2277	319	8	kda	kda	NOUN
dti-2277	319	9	cyclophilin	cyclophilin	PROPN
dti-2277	319	10	-	-	PUNCT
dti-2277	319	11	related	relate	VERB
dti-2277	319	12	protein	protein	NOUN
dti-2277	319	13	.	.	PUNCT
dti-2277	320	1	j.	j.	PROPN
dti-2277	320	2	biol	biol	PROPN
dti-2277	320	3	.	.	PUNCT
dti-2277	321	1	chem	chem	PROPN
dti-2277	321	2	.	.	PUNCT
dti-2277	321	3	,	,	PUNCT
dti-2277	321	4	267:5503–5507	267:5503–5507	NUM
dti-2277	321	5	.	.	PUNCT
dti-2277	322	1	kootstra	kootstra	PROPN
dti-2277	322	2	,	,	PUNCT
dti-2277	322	3	n.a	n.a	PROPN
dti-2277	322	4	.	.	PROPN
dti-2277	322	5	,	,	PUNCT
dti-2277	322	6	munk	munk	NOUN
dti-2277	322	7	,	,	PUNCT
dti-2277	322	8	c.	c.	PROPN
dti-2277	322	9	,	,	PUNCT
dti-2277	322	10	tonnu	tonnu	NOUN
dti-2277	322	11	,	,	PUNCT
dti-2277	322	12	n.	n.	NOUN
dti-2277	322	13	,	,	PUNCT
dti-2277	322	14	landau	landau	NOUN
dti-2277	322	15	,	,	PUNCT
dti-2277	322	16	n.r	n.r	PROPN
dti-2277	322	17	.	.	PROPN
dti-2277	322	18	and	and	CCONJ
dti-2277	322	19	verma	verma	PROPN
dti-2277	322	20	,	,	PUNCT
dti-2277	322	21	i.m	i.m	PROPN
dti-2277	322	22	.	.	PROPN
dti-2277	322	23	2003	2003	NUM
dti-2277	322	24	.	.	PUNCT
dti-2277	323	1	abrogation	abrogation	NOUN
dti-2277	323	2	of	of	ADP
dti-2277	323	3	postentry	postentry	NOUN
dti-2277	323	4	restriction	restriction	NOUN
dti-2277	323	5	of	of	ADP
dti-2277	323	6	hiv-1	hiv-1	X
dti-2277	323	7	-	-	PUNCT
dti-2277	323	8	based	base	VERB
dti-2277	323	9	lentiviral	lentiviral	ADJ
dti-2277	323	10	vector	vector	NOUN
dti-2277	323	11	transduction	transduction	NOUN
dti-2277	323	12	in	in	ADP
dti-2277	323	13	simian	simian	ADJ
dti-2277	323	14	cells	cell	NOUN
dti-2277	323	15	.	.	PUNCT
dti-2277	324	1	proc	proc	NOUN
dti-2277	324	2	.	.	PUNCT
dti-2277	325	1	natl	natl	PROPN
dti-2277	325	2	.	.	PUNCT
dti-2277	326	1	acad	acad	PROPN
dti-2277	326	2	.	.	PUNCT
dti-2277	327	1	sci	sci	PROPN
dti-2277	327	2	.	.	PUNCT
dti-2277	327	3	u.s.a	u.s.a	PROPN
dti-2277	327	4	.	.	PROPN
dti-2277	327	5	,	,	PUNCT
dti-2277	328	1	100	100	NUM
dti-2277	328	2	:	:	SYM
dti-2277	328	3	1298–1303	1298–1303	NUM
dti-2277	328	4	.	.	PUNCT
dti-2277	328	5	krummrei	krummrei	PROPN
dti-2277	328	6	,	,	PUNCT
dti-2277	328	7	u.	u.	PROPN
dti-2277	328	8	,	,	PUNCT
dti-2277	328	9	bang	bang	PROPN
dti-2277	328	10	,	,	PUNCT
dti-2277	328	11	r.	r.	PROPN
dti-2277	328	12	,	,	PUNCT
dti-2277	328	13	schmidtchen	schmidtchen	ADV
dti-2277	328	14	,	,	PUNCT
dti-2277	328	15	r.	r.	PROPN
dti-2277	328	16	,	,	PUNCT
dti-2277	328	17	brune	brune	PROPN
dti-2277	328	18	,	,	PUNCT
dti-2277	328	19	k.	k.	PROPN
dti-2277	328	20	and	and	CCONJ
dti-2277	328	21	bang	bang	PROPN
dti-2277	328	22	,	,	PUNCT
dti-2277	328	23	h.	h.	PROPN
dti-2277	328	24	1995	1995	NUM
dti-2277	328	25	.	.	PUNCT
dti-2277	329	1	cyclophilin	cyclophilin	PROPN
dti-2277	329	2	-	-	PUNCT
dti-2277	329	3	a	a	PROPN
dti-2277	329	4	is	be	AUX
dti-2277	329	5	a	a	DET
dti-2277	329	6	zinc	zinc	NOUN
dti-2277	329	7	-	-	PUNCT
dti-2277	329	8	dependent	dependent	ADJ
dti-2277	329	9	dna	dna	NOUN
dti-2277	329	10	binding	bind	VERB
dti-2277	329	11	protein	protein	NOUN
dti-2277	329	12	in	in	ADP
dti-2277	329	13	macrophages	macrophage	NOUN
dti-2277	329	14	.	.	PUNCT
dti-2277	330	1	febs	febs	NOUN
dti-2277	330	2	.	.	PUNCT
dti-2277	331	1	lett	lett	PROPN
dti-2277	331	2	.	.	PROPN
dti-2277	331	3	,	,	PUNCT
dti-2277	331	4	371:47–51	371:47–51	X
dti-2277	331	5	.	.	X
dti-2277	331	6	liang	liang	PROPN
dti-2277	331	7	,	,	PUNCT
dti-2277	331	8	t.j	t.j	PROPN
dti-2277	331	9	.	.	PROPN
dti-2277	331	10	,	,	PUNCT
dti-2277	331	11	jeffers	jeffers	PROPN
dti-2277	331	12	,	,	PUNCT
dti-2277	331	13	l.j	l.j	PROPN
dti-2277	331	14	.	.	PROPN
dti-2277	331	15	,	,	PUNCT
dti-2277	331	16	reddy	reddy	PROPN
dti-2277	331	17	,	,	PUNCT
dti-2277	331	18	k.r	k.r	PROPN
dti-2277	331	19	.	.	PROPN
dti-2277	331	20	,	,	PUNCT
dti-2277	331	21	de	de	PROPN
dti-2277	331	22	medina	medina	PROPN
dti-2277	331	23	,	,	PUNCT
dti-2277	331	24	m.	m.	NOUN
dti-2277	331	25	,	,	PUNCT
dti-2277	331	26	parker	parker	PROPN
dti-2277	331	27	,	,	PUNCT
dti-2277	331	28	i.t	i.t	PROPN
dti-2277	331	29	.	.	PROPN
dti-2277	331	30	,	,	PUNCT
dti-2277	331	31	cheinquer	cheinquer	PROPN
dti-2277	331	32	,	,	PUNCT
dti-2277	331	33	h.	h.	PROPN
dti-2277	331	34	,	,	PUNCT
dti-2277	331	35	idrovo	idrovo	PROPN
dti-2277	331	36	,	,	PUNCT
dti-2277	331	37	v.	v.	ADV
dti-2277	331	38	,	,	PUNCT
dti-2277	331	39	rabassa	rabassa	NOUN
dti-2277	331	40	,	,	PUNCT
dti-2277	331	41	a.	a.	NOUN
dti-2277	331	42	and	and	CCONJ
dti-2277	331	43	schiff	schiff	PROPN
dti-2277	331	44	,	,	PUNCT
dti-2277	331	45	e.r	e.r	PROPN
dti-2277	331	46	.	.	PROPN
dti-2277	331	47	1993	1993	NUM
dti-2277	331	48	.	.	PUNCT
dti-2277	332	1	viral	viral	ADJ
dti-2277	332	2	pathogenesis	pathogenesis	NOUN
dti-2277	332	3	of	of	ADP
dti-2277	332	4	hepatocellular	hepatocellular	ADJ
dti-2277	332	5	carcinoma	carcinoma	NOUN
dti-2277	332	6	in	in	ADP
dti-2277	332	7	the	the	DET
dti-2277	332	8	united	united	PROPN
dti-2277	332	9	states	states	PROPN
dti-2277	332	10	.	.	PUNCT
dti-2277	333	1	hepatology	hepatology	NOUN
dti-2277	333	2	,	,	PUNCT
dti-2277	333	3	18:1326–1333	18:1326–1333	NUM
dti-2277	333	4	.	.	PUNCT
dti-2277	334	1	liu	liu	PROPN
dti-2277	334	2	,	,	PUNCT
dti-2277	334	3	j.	j.	PROPN
dti-2277	334	4	,	,	PUNCT
dti-2277	334	5	albers	albers	PROPN
dti-2277	334	6	,	,	PUNCT
dti-2277	334	7	m.w	m.w	PROPN
dti-2277	334	8	.	.	PROPN
dti-2277	334	9	,	,	PUNCT
dti-2277	334	10	chen	chen	PROPN
dti-2277	334	11	,	,	PUNCT
dti-2277	334	12	c.m	c.m	PROPN
dti-2277	334	13	.	.	PROPN
dti-2277	334	14	,	,	PUNCT
dti-2277	334	15	schreiber	schreiber	PROPN
dti-2277	334	16	,	,	PUNCT
dti-2277	334	17	s.l	s.l	PROPN
dti-2277	334	18	.	.	PROPN
dti-2277	334	19	and	and	CCONJ
dti-2277	334	20	walsh	walsh	PROPN
dti-2277	334	21	,	,	PUNCT
dti-2277	334	22	c.t	c.t	PROPN
dti-2277	334	23	.	.	PROPN
dti-2277	334	24	1990	1990	NUM
dti-2277	334	25	.	.	PUNCT
dti-2277	335	1	cloning	cloning	NOUN
dti-2277	335	2	,	,	PUNCT
dti-2277	335	3	expression	expression	NOUN
dti-2277	335	4	,	,	PUNCT
dti-2277	335	5	and	and	CCONJ
dti-2277	335	6	purifi	purifi	ADJ
dti-2277	335	7	cation	cation	NOUN
dti-2277	335	8	of	of	ADP
dti-2277	335	9	human	human	ADJ
dti-2277	335	10	cyclophilin	cyclophilin	PROPN
dti-2277	335	11	in	in	ADP
dti-2277	335	12	escherichia	escherichia	NOUN
dti-2277	335	13	coli	coli	NOUN
dti-2277	335	14	and	and	CCONJ
dti-2277	335	15	assessment	assessment	NOUN
dti-2277	335	16	of	of	ADP
dti-2277	335	17	the	the	DET
dti-2277	335	18	catalytic	catalytic	ADJ
dti-2277	335	19	role	role	NOUN
dti-2277	335	20	of	of	ADP
dti-2277	335	21	cysteines	cysteine	NOUN
dti-2277	335	22	by	by	ADP
dti-2277	335	23	sitedirected	sitedirected	ADJ
dti-2277	335	24	mutagenesis	mutagenesis	NOUN
dti-2277	335	25	.	.	PUNCT
dti-2277	336	1	proc	proc	PROPN
dti-2277	336	2	.	.	PUNCT
dti-2277	337	1	natl	natl	PROPN
dti-2277	337	2	.	.	PUNCT
dti-2277	338	1	acad	acad	PROPN
dti-2277	338	2	.	.	PUNCT
dti-2277	339	1	sci	sci	PROPN
dti-2277	339	2	.	.	PUNCT
dti-2277	339	3	u.s.a	u.s.a	PROPN
dti-2277	339	4	.	.	PROPN
dti-2277	339	5	,	,	PUNCT
dti-2277	339	6	87:2304–2308	87:2304–2308	NUM
dti-2277	339	7	.	.	PUNCT
dti-2277	340	1	liu	liu	PROPN
dti-2277	340	2	,	,	PUNCT
dti-2277	340	3	j.	j.	PROPN
dti-2277	340	4	,	,	PUNCT
dti-2277	340	5	albers	albers	PROPN
dti-2277	340	6	,	,	PUNCT
dti-2277	340	7	m.w	m.w	PROPN
dti-2277	340	8	.	.	PROPN
dti-2277	340	9	,	,	PUNCT
dti-2277	340	10	wandless	wandless	NOUN
dti-2277	340	11	,	,	PUNCT
dti-2277	340	12	t.j	t.j	PROPN
dti-2277	340	13	.	.	PROPN
dti-2277	340	14	,	,	PUNCT
dti-2277	340	15	luan	luan	PROPN
dti-2277	340	16	,	,	PUNCT
dti-2277	340	17	s.	s.	PROPN
dti-2277	340	18	,	,	PUNCT
dti-2277	340	19	alberg	alberg	PROPN
dti-2277	340	20	,	,	PUNCT
dti-2277	340	21	d.g	d.g	PROPN
dti-2277	340	22	.	.	PROPN
dti-2277	340	23	,	,	PUNCT
dti-2277	340	24	belshaw	belshaw	NOUN
dti-2277	340	25	,	,	PUNCT
dti-2277	340	26	p.	p.	PROPN
dti-2277	340	27	j.	j.	PROPN
dti-2277	340	28	,	,	PUNCT
dti-2277	340	29	cohen	cohen	PROPN
dti-2277	340	30	,	,	PUNCT
dti-2277	340	31	p.	p.	PROPN
dti-2277	340	32	,	,	PUNCT
dti-2277	340	33	mackintosh	mackintosh	PROPN
dti-2277	340	34	,	,	PUNCT
dti-2277	340	35	c.	c.	PROPN
dti-2277	340	36	,	,	PUNCT
dti-2277	340	37	klee	klee	PROPN
dti-2277	340	38	,	,	PUNCT
dti-2277	340	39	c.b	c.b	PROPN
dti-2277	340	40	.	.	PROPN
dti-2277	340	41	and	and	CCONJ
dti-2277	340	42	schreiber	schreiber	PROPN
dti-2277	340	43	,	,	PUNCT
dti-2277	340	44	s.l	s.l	PROPN
dti-2277	340	45	.	.	PROPN
dti-2277	340	46	1992	1992	NUM
dti-2277	340	47	.	.	PUNCT
dti-2277	341	1	inhibition	inhibition	NOUN
dti-2277	341	2	of	of	ADP
dti-2277	341	3	t	t	NOUN
dti-2277	341	4	cell	cell	NOUN
dti-2277	341	5	signaling	signal	VERB
dti-2277	341	6	by	by	ADP
dti-2277	341	7	immunophilin	immunophilin	NOUN
dti-2277	341	8	-	-	PUNCT
dti-2277	341	9	ligand	ligand	ADJ
dti-2277	341	10	complexes	complex	NOUN
dti-2277	341	11	correlates	correlate	VERB
dti-2277	341	12	with	with	ADP
dti-2277	341	13	loss	loss	NOUN
dti-2277	341	14	of	of	ADP
dti-2277	341	15	calcineurin	calcineurin	ADJ
dti-2277	341	16	phosphatase	phosphatase	NOUN
dti-2277	341	17	activity	activity	NOUN
dti-2277	341	18	.	.	PUNCT
dti-2277	342	1	biochemistry	biochemistry	NOUN
dti-2277	342	2	.	.	PUNCT
dti-2277	342	3	,	,	PUNCT
dti-2277	343	1	31:3896–3901	31:3896–3901	X
dti-2277	343	2	.	.	PUNCT
dti-2277	344	1	liu	liu	PROPN
dti-2277	344	2	,	,	PUNCT
dti-2277	344	3	j.	j.	PROPN
dti-2277	344	4	,	,	PUNCT
dti-2277	344	5	farmer	farmer	NOUN
dti-2277	344	6	,	,	PUNCT
dti-2277	344	7	j.d	j.d	PROPN
dti-2277	344	8	.	.	PROPN
dti-2277	344	9	jr	jr	PROPN
dti-2277	344	10	.	.	PROPN
dti-2277	344	11	,	,	PUNCT
dti-2277	344	12	lane	lane	PROPN
dti-2277	344	13	,	,	PUNCT
dti-2277	344	14	w.s	w.s	PROPN
dti-2277	344	15	.	.	PROPN
dti-2277	344	16	,	,	PUNCT
dti-2277	344	17	friedman	friedman	PROPN
dti-2277	344	18	,	,	PUNCT
dti-2277	344	19	j.	j.	PROPN
dti-2277	344	20	,	,	PUNCT
dti-2277	344	21	weissman	weissman	PROPN
dti-2277	344	22	,	,	PUNCT
dti-2277	344	23	i.	i.	PROPN
dti-2277	344	24	and	and	CCONJ
dti-2277	344	25	schreiber	schreiber	PROPN
dti-2277	344	26	,	,	PUNCT
dti-2277	344	27	s.l	s.l	PROPN
dti-2277	344	28	.	.	PROPN
dti-2277	344	29	1991	1991	NUM
dti-2277	344	30	.	.	PUNCT
dti-2277	345	1	calcineurin	calcineurin	PROPN
dti-2277	345	2	is	be	AUX
dti-2277	345	3	a	a	DET
dti-2277	345	4	common	common	ADJ
dti-2277	345	5	target	target	NOUN
dti-2277	345	6	of	of	ADP
dti-2277	345	7	cyclophilin	cyclophilin	PROPN
dti-2277	345	8	-	-	PUNCT
dti-2277	345	9	cyclosporin	cyclosporin	NOUN
dti-2277	345	10	a	a	PRON
dti-2277	345	11	and	and	CCONJ
dti-2277	345	12	fkbp	fkbp	ADJ
dti-2277	345	13	-	-	PUNCT
dti-2277	345	14	fk506	fk506	NOUN
dti-2277	345	15	complexes	complex	NOUN
dti-2277	345	16	.	.	PUNCT
dti-2277	346	1	cell	cell	NOUN
dti-2277	346	2	,	,	PUNCT
dti-2277	346	3	66:807–815	66:807–815	PROPN
dti-2277	346	4	.	.	PUNCT
dti-2277	347	1	lohmann	lohmann	PROPN
dti-2277	347	2	,	,	PUNCT
dti-2277	347	3	v.	v.	PROPN
dti-2277	347	4	,	,	PUNCT
dti-2277	347	5	korner	korner	PROPN
dti-2277	347	6	,	,	PUNCT
dti-2277	347	7	f.	f.	PROPN
dti-2277	347	8	,	,	PUNCT
dti-2277	347	9	koch	koch	PROPN
dti-2277	347	10	,	,	PUNCT
dti-2277	347	11	j.	j.	PROPN
dti-2277	347	12	,	,	PUNCT
dti-2277	347	13	herian	herian	NOUN
dti-2277	347	14	,	,	PUNCT
dti-2277	347	15	u.	u.	PROPN
dti-2277	347	16	,	,	PUNCT
dti-2277	347	17	theilmann	theilmann	PROPN
dti-2277	347	18	,	,	PUNCT
dti-2277	347	19	l.	l.	PROPN
dti-2277	347	20	and	and	CCONJ
dti-2277	347	21	bartenschlager	bartenschlager	PROPN
dti-2277	347	22	,	,	PUNCT
dti-2277	347	23	r.	r.	PROPN
dti-2277	347	24	1999	1999	NUM
dti-2277	347	25	.	.	PUNCT
dti-2277	348	1	replication	replication	NOUN
dti-2277	348	2	of	of	ADP
dti-2277	348	3	subgenomic	subgenomic	ADJ
dti-2277	348	4	hepatitis	hepatitis	PROPN
dti-2277	348	5	c	c	PROPN
dti-2277	348	6	virus	virus	NOUN
dti-2277	348	7	rnas	rna	VERB
dti-2277	348	8	in	in	ADP
dti-2277	348	9	a	a	DET
dti-2277	348	10	hepatoma	hepatoma	ADJ
dti-2277	348	11	cell	cell	NOUN
dti-2277	348	12	line	line	NOUN
dti-2277	348	13	.	.	PUNCT
dti-2277	349	1	science	science	NOUN
dti-2277	349	2	,	,	PUNCT
dti-2277	349	3	285:110–113	285:110–113	NUM
dti-2277	349	4	.	.	PUNCT
dti-2277	350	1	luban	luban	PROPN
dti-2277	350	2	,	,	PUNCT
dti-2277	350	3	j.	j.	PROPN
dti-2277	350	4	,	,	PUNCT
dti-2277	350	5	bossolt	bossolt	PROPN
dti-2277	350	6	,	,	PUNCT
dti-2277	350	7	k.l	k.l	PROPN
dti-2277	350	8	.	.	PROPN
dti-2277	350	9	,	,	PUNCT
dti-2277	350	10	franke	franke	PROPN
dti-2277	350	11	,	,	PUNCT
dti-2277	350	12	e.k	e.k	PROPN
dti-2277	350	13	.	.	PROPN
dti-2277	350	14	,	,	PUNCT
dti-2277	350	15	kalpana	kalpana	PROPN
dti-2277	350	16	,	,	PUNCT
dti-2277	350	17	g.v	g.v	PROPN
dti-2277	350	18	.	.	PROPN
dti-2277	350	19	and	and	CCONJ
dti-2277	350	20	goff	goff	PROPN
dti-2277	350	21	,	,	PUNCT
dti-2277	350	22	s.p	s.p	PROPN
dti-2277	350	23	.	.	PROPN
dti-2277	350	24	1993	1993	NUM
dti-2277	350	25	.	.	PUNCT
dti-2277	351	1	human	human	ADJ
dti-2277	351	2	immunodefi	immunodefi	PROPN
dti-2277	351	3	ciency	ciency	NOUN
dti-2277	351	4	virus	virus	NOUN
dti-2277	351	5	type	type	NOUN
dti-2277	351	6	1	1	NUM
dti-2277	351	7	gag	gag	NOUN
dti-2277	351	8	protein	protein	NOUN
dti-2277	351	9	binds	bind	VERB
dti-2277	351	10	to	to	PART
dti-2277	351	11	cyclophilins	cyclophilin	NOUN
dti-2277	351	12	a	a	DET
dti-2277	351	13	and	and	CCONJ
dti-2277	351	14	b.	b.	NOUN
dti-2277	351	15	cell	cell	NOUN
dti-2277	351	16	.	.	PUNCT
dti-2277	351	17	,	,	PUNCT
dti-2277	351	18	73:1067–1078	73:1067–1078	X
dti-2277	351	19	.	.	PUNCT
dti-2277	351	20	luban	luban	PROPN
dti-2277	351	21	,	,	PUNCT
dti-2277	351	22	j.	j.	PROPN
dti-2277	351	23	(	(	PUNCT
dti-2277	351	24	in	in	ADP
dti-2277	351	25	press	press	NOUN
dti-2277	351	26	)	)	PUNCT
dti-2277	351	27	.	.	PUNCT
dti-2277	352	1	cyclophilin	cyclophilin	PROPN
dti-2277	352	2	a	a	PRON
dti-2277	352	3	,	,	PUNCT
dti-2277	352	4	trim5	trim5	NOUN
dti-2277	352	5	and	and	CCONJ
dti-2277	352	6	resistance	resistance	NOUN
dti-2277	352	7	to	to	ADP
dti-2277	352	8	hiv-1	hiv-1	ADJ
dti-2277	352	9	infection	infection	NOUN
dti-2277	352	10	.	.	PUNCT
dti-2277	353	1	j.	j.	PROPN
dti-2277	353	2	virol	virol	PROPN
dti-2277	353	3	.	.	PUNCT
dti-2277	353	4	,	,	PUNCT
dti-2277	354	1	[	[	X
dti-2277	354	2	epub	epub	NOUN
dti-2277	354	3	ahead	ahead	ADV
dti-2277	354	4	of	of	ADP
dti-2277	354	5	print	print	NOUN
dti-2277	354	6	]	]	PUNCT
dti-2277	354	7	.	.	PUNCT
dti-2277	355	1	luo	luo	PROPN
dti-2277	355	2	,	,	PUNCT
dti-2277	355	3	c.	c.	PROPN
dti-2277	355	4	,	,	PUNCT
dti-2277	355	5	luo	luo	PROPN
dti-2277	355	6	,	,	PUNCT
dti-2277	355	7	h.	h.	PROPN
dti-2277	355	8	,	,	PUNCT
dti-2277	355	9	zheng	zheng	PROPN
dti-2277	355	10	,	,	PUNCT
dti-2277	355	11	s.	s.	PROPN
dti-2277	355	12	,	,	PUNCT
dti-2277	355	13	gui	gui	PROPN
dti-2277	355	14	,	,	PUNCT
dti-2277	355	15	c.	c.	PROPN
dti-2277	355	16	,	,	PUNCT
dti-2277	355	17	yue	yue	PROPN
dti-2277	355	18	,	,	PUNCT
dti-2277	355	19	l.	l.	PROPN
dti-2277	355	20	,	,	PUNCT
dti-2277	355	21	yu	yu	PROPN
dti-2277	355	22	,	,	PUNCT
dti-2277	355	23	c.	c.	PROPN
dti-2277	355	24	,	,	PUNCT
dti-2277	355	25	sun	sun	NOUN
dti-2277	355	26	,	,	PUNCT
dti-2277	355	27	t.	t.	PROPN
dti-2277	355	28	,	,	PUNCT
dti-2277	355	29	he	he	PRON
dti-2277	355	30	,	,	PUNCT
dti-2277	355	31	p.	p.	PROPN
dti-2277	355	32	,	,	PUNCT
dti-2277	355	33	chen	chen	PROPN
dti-2277	355	34	,	,	PUNCT
dti-2277	355	35	j.	j.	PROPN
dti-2277	355	36	,	,	PUNCT
dti-2277	355	37	shen	shen	PROPN
dti-2277	355	38	,	,	PUNCT
dti-2277	355	39	j.	j.	PROPN
dti-2277	355	40	et	et	PROPN
dti-2277	355	41	al	al	PROPN
dti-2277	355	42	.	.	PROPN
dti-2277	355	43	2004	2004	NUM
dti-2277	355	44	.	.	PUNCT
dti-2277	356	1	nucleocapsid	nucleocapsid	ADJ
dti-2277	356	2	protein	protein	NOUN
dti-2277	356	3	of	of	ADP
dti-2277	356	4	sars	sars	PROPN
dti-2277	356	5	coronavirus	coronavirus	PROPN
dti-2277	356	6	tightly	tightly	ADV
dti-2277	356	7	binds	bind	VERB
dti-2277	356	8	to	to	ADP
dti-2277	356	9	human	human	PROPN
dti-2277	356	10	cyclophilin	cyclophilin	PROPN
dti-2277	356	11	a.	a.	PROPN
dti-2277	356	12	biochem	biochem	PROPN
dti-2277	356	13	.	.	PUNCT
dti-2277	357	1	biophys	biophy	NOUN
dti-2277	357	2	.	.	PUNCT
dti-2277	358	1	res	re	NOUN
dti-2277	358	2	.	.	PUNCT
dti-2277	359	1	commun	commun	PROPN
dti-2277	359	2	.	.	PROPN
dti-2277	359	3	,	,	PUNCT
dti-2277	359	4	321:557–565	321:557–565	NUM
dti-2277	359	5	.	.	PUNCT
dti-2277	360	1	mccaffrey	mccaffrey	PROPN
dti-2277	360	2	,	,	PUNCT
dti-2277	360	3	p.g	p.g	PROPN
dti-2277	360	4	.	.	PROPN
dti-2277	360	5	,	,	PUNCT
dti-2277	360	6	perrino	perrino	PROPN
dti-2277	360	7	,	,	PUNCT
dti-2277	360	8	b.a	b.a	PROPN
dti-2277	360	9	.	.	PROPN
dti-2277	360	10	,	,	PUNCT
dti-2277	360	11	soderling	soderling	PROPN
dti-2277	360	12	,	,	PUNCT
dti-2277	360	13	t.r	t.r	PROPN
dti-2277	360	14	.	.	PROPN
dti-2277	360	15	and	and	CCONJ
dti-2277	360	16	rao	rao	PROPN
dti-2277	360	17	,	,	PUNCT
dti-2277	360	18	a.	a.	NOUN
dti-2277	360	19	1993	1993	NUM
dti-2277	360	20	.	.	PUNCT
dti-2277	361	1	nf	nf	X
dti-2277	361	2	-	-	PUNCT
dti-2277	361	3	atp	atp	PROPN
dti-2277	361	4	,	,	PUNCT
dti-2277	361	5	a	a	DET
dti-2277	361	6	t	t	NOUN
dti-2277	361	7	lymphocyte	lymphocyte	NOUN
dti-2277	361	8	dna	dna	NOUN
dti-2277	361	9	-	-	PUNCT
dti-2277	361	10	binding	bind	VERB
dti-2277	361	11	protein	protein	NOUN
dti-2277	361	12	that	that	PRON
dti-2277	361	13	is	be	AUX
dti-2277	361	14	a	a	DET
dti-2277	361	15	target	target	NOUN
dti-2277	361	16	for	for	ADP
dti-2277	361	17	calcineurin	calcineurin	NOUN
dti-2277	361	18	and	and	CCONJ
dti-2277	361	19	immunosuppressive	immunosuppressive	ADJ
dti-2277	361	20	drugs	drug	NOUN
dti-2277	361	21	.	.	PUNCT
dti-2277	362	1	j.	j.	PROPN
dti-2277	362	2	biol	biol	PROPN
dti-2277	362	3	.	.	PUNCT
dti-2277	363	1	chem	chem	PROPN
dti-2277	363	2	.	.	PUNCT
dti-2277	363	3	,	,	PUNCT
dti-2277	363	4	268:3747–3752	268:3747–3752	NUM
dti-2277	363	5	.	.	PUNCT
dti-2277	363	6	mi	mi	PROPN
dti-2277	363	7	,	,	PUNCT
dti-2277	363	8	h.	h.	PROPN
dti-2277	363	9	,	,	PUNCT
dti-2277	363	10	kops	kop	NOUN
dti-2277	363	11	,	,	PUNCT
dti-2277	363	12	o.	o.	PROPN
dti-2277	363	13	,	,	PUNCT
dti-2277	363	14	zimmermann	zimmermann	PROPN
dti-2277	363	15	,	,	PUNCT
dti-2277	363	16	e.	e.	PROPN
dti-2277	363	17	,	,	PUNCT
dti-2277	363	18	jaschke	jaschke	PROPN
dti-2277	363	19	,	,	PUNCT
dti-2277	363	20	a.	a.	NOUN
dti-2277	363	21	and	and	CCONJ
dti-2277	363	22	tropschug	tropschug	VERB
dti-2277	363	23	,	,	PUNCT
dti-2277	363	24	m.	m.	NOUN
dti-2277	363	25	1996	1996	NUM
dti-2277	363	26	.	.	PUNCT
dti-2277	364	1	a	a	DET
dti-2277	364	2	nuclear	nuclear	ADJ
dti-2277	364	3	rna	rna	NOUN
dti-2277	364	4	-	-	PUNCT
dti-2277	364	5	binding	bind	VERB
dti-2277	364	6	cyclophilin	cyclophilin	NOUN
dti-2277	364	7	in	in	ADP
dti-2277	364	8	human	human	PROPN
dti-2277	364	9	t	t	PROPN
dti-2277	364	10	cells	cell	NOUN
dti-2277	364	11	.	.	PUNCT
dti-2277	365	1	febs	febs	NOUN
dti-2277	365	2	.	.	PUNCT
dti-2277	366	1	lett	lett	PROPN
dti-2277	366	2	.	.	PROPN
dti-2277	366	3	,	,	PUNCT
dti-2277	366	4	398:201–205	398:201–205	NUM
dti-2277	366	5	.	.	PUNCT
dti-2277	367	1	mlynar	mlynar	PROPN
dti-2277	367	2	,	,	PUNCT
dti-2277	367	3	e.	e.	PROPN
dti-2277	367	4	,	,	PUNCT
dti-2277	367	5	bevec	bevec	PROPN
dti-2277	367	6	,	,	PUNCT
dti-2277	367	7	d.	d.	PROPN
dti-2277	367	8	,	,	PUNCT
dti-2277	367	9	billich	billich	PROPN
dti-2277	367	10	,	,	PUNCT
dti-2277	367	11	a.	a.	PROPN
dti-2277	367	12	,	,	PUNCT
dti-2277	367	13	rosenwirth	rosenwirth	PROPN
dti-2277	367	14	,	,	PUNCT
dti-2277	367	15	b.	b.	PROPN
dti-2277	367	16	and	and	CCONJ
dti-2277	367	17	steinkasserer	steinkasserer	NOUN
dti-2277	367	18	,	,	PUNCT
dti-2277	367	19	a.	a.	NOUN
dti-2277	367	20	1997	1997	NUM
dti-2277	367	21	.	.	PUNCT
dti-2277	368	1	the	the	DET
dti-2277	368	2	non	non	ADJ
dti-2277	368	3	-	-	ADJ
dti-2277	368	4	immunosuppressive	immunosuppressive	ADJ
dti-2277	368	5	cyclosporin	cyclosporin	NOUN
dti-2277	368	6	a	a	DET
dti-2277	368	7	analogue	analogue	NOUN
dti-2277	368	8	sdz	sdz	PROPN
dti-2277	368	9	nim	nim	PROPN
dti-2277	368	10	811	811	NUM
dti-2277	368	11	inhibits	inhibit	VERB
dti-2277	368	12	cyclophilin	cyclophilin	PROPN
dti-2277	368	13	a	a	DET
dti-2277	368	14	incorporation	incorporation	NOUN
dti-2277	368	15	into	into	ADP
dti-2277	368	16	virions	virion	NOUN
dti-2277	368	17	and	and	CCONJ
dti-2277	368	18	virus	virus	NOUN
dti-2277	368	19	replication	replication	NOUN
dti-2277	368	20	in	in	ADP
dti-2277	368	21	human	human	ADJ
dti-2277	368	22	immunodefi	immunodefi	PROPN
dti-2277	368	23	ciency	ciency	NOUN
dti-2277	368	24	virus	virus	NOUN
dti-2277	368	25	type	type	NOUN
dti-2277	368	26	1	1	NUM
dti-2277	368	27	-	-	PUNCT
dti-2277	368	28	infected	infect	VERB
dti-2277	368	29	primary	primary	ADJ
dti-2277	368	30	and	and	CCONJ
dti-2277	368	31	growth	growth	NOUN
dti-2277	368	32	-	-	PUNCT
dti-2277	368	33	arrested	arrest	VERB
dti-2277	368	34	t	t	NOUN
dti-2277	368	35	cells	cell	NOUN
dti-2277	368	36	.	.	PUNCT
dti-2277	369	1	j.	j.	PROPN
dti-2277	369	2	gen	gen	PROPN
dti-2277	369	3	.	.	PROPN
dti-2277	369	4	virol	virol	PROPN
dti-2277	369	5	.	.	PUNCT
dti-2277	369	6	,	,	PUNCT
dti-2277	369	7	78	78	NUM
dti-2277	369	8	(	(	PUNCT
dti-2277	369	9	pt	pt	PROPN
dti-2277	369	10	4):825	4):825	PROPN
dti-2277	369	11	–	–	PUNCT
dti-2277	369	12	835	835	NUM
dti-2277	369	13	.	.	PUNCT
dti-2277	370	1	nakagawa	nakagawa	PROPN
dti-2277	370	2	,	,	PUNCT
dti-2277	370	3	m.	m.	NOUN
dti-2277	370	4	,	,	PUNCT
dti-2277	370	5	sakamoto	sakamoto	NOUN
dti-2277	370	6	,	,	PUNCT
dti-2277	370	7	n.	n.	NOUN
dti-2277	370	8	,	,	PUNCT
dti-2277	370	9	enomoto	enomoto	NOUN
dti-2277	370	10	,	,	PUNCT
dti-2277	370	11	n.	n.	NOUN
dti-2277	370	12	,	,	PUNCT
dti-2277	370	13	tanabe	tanabe	PROPN
dti-2277	370	14	,	,	PUNCT
dti-2277	370	15	y.	y.	PROPN
dti-2277	370	16	,	,	PUNCT
dti-2277	370	17	kanazawa	kanazawa	PROPN
dti-2277	370	18	,	,	PUNCT
dti-2277	370	19	n.	n.	PROPN
dti-2277	370	20	,	,	PUNCT
dti-2277	370	21	koyama	koyama	PROPN
dti-2277	370	22	,	,	PUNCT
dti-2277	370	23	t.	t.	PROPN
dti-2277	370	24	,	,	PUNCT
dti-2277	370	25	kurosaki	kurosaki	PROPN
dti-2277	370	26	,	,	PUNCT
dti-2277	370	27	m.	m.	NOUN
dti-2277	370	28	,	,	PUNCT
dti-2277	370	29	maekawa	maekawa	PROPN
dti-2277	370	30	,	,	PUNCT
dti-2277	370	31	s.	s.	PROPN
dti-2277	370	32	,	,	PUNCT
dti-2277	370	33	yamashiro	yamashiro	NOUN
dti-2277	370	34	,	,	PUNCT
dti-2277	370	35	t.	t.	PROPN
dti-2277	370	36	,	,	PUNCT
dti-2277	370	37	chen	chen	PROPN
dti-2277	370	38	,	,	PUNCT
dti-2277	370	39	c.	c.	PROPN
dti-2277	370	40	h.	h.	PROPN
dti-2277	370	41	et	et	PROPN
dti-2277	370	42	al	al	PROPN
dti-2277	370	43	.	.	PROPN
dti-2277	370	44	2004	2004	NUM
dti-2277	370	45	.	.	PUNCT
dti-2277	371	1	specifi	specifi	PROPN
dti-2277	371	2	c	c	PROPN
dti-2277	371	3	inhibition	inhibition	NOUN
dti-2277	371	4	of	of	ADP
dti-2277	371	5	hepatitis	hepatitis	PROPN
dti-2277	371	6	c	c	PROPN
dti-2277	371	7	virus	virus	NOUN
dti-2277	371	8	replication	replication	NOUN
dti-2277	371	9	by	by	ADP
dti-2277	371	10	cyclosporin	cyclosporin	NOUN
dti-2277	371	11	a.	a.	PROPN
dti-2277	371	12	biochem	biochem	PROPN
dti-2277	371	13	.	.	PUNCT
dti-2277	372	1	biophys	biophy	NOUN
dti-2277	372	2	.	.	PUNCT
dti-2277	373	1	res	re	NOUN
dti-2277	373	2	.	.	PUNCT
dti-2277	374	1	commun	commun	PROPN
dti-2277	374	2	.	.	PROPN
dti-2277	374	3	,	,	PUNCT
dti-2277	374	4	313:42–47	313:42–47	X
dti-2277	374	5	.	.	PUNCT
dti-2277	374	6	drug	drug	NOUN
dti-2277	374	7	target	target	NOUN
dti-2277	374	8	insights	insight	NOUN
dti-2277	374	9	2007	2007	NUM
dti-2277	374	10	:	:	PUNCT
dti-2277	374	11	2	2	NUM
dti-2277	374	12	17	17	NUM
dti-2277	374	13	cyclophilin	cyclophilin	NOUN
dti-2277	374	14	and	and	CCONJ
dti-2277	374	15	viruses	virus	NOUN
dti-2277	374	16	nakagawa	nakagawa	PROPN
dti-2277	374	17	,	,	PUNCT
dti-2277	374	18	t.	t.	PROPN
dti-2277	374	19	,	,	PUNCT
dti-2277	374	20	shimizu	shimizu	PROPN
dti-2277	374	21	,	,	PUNCT
dti-2277	374	22	s.	s.	PROPN
dti-2277	374	23	,	,	PUNCT
dti-2277	374	24	watanabe	watanabe	PROPN
dti-2277	374	25	,	,	PUNCT
dti-2277	374	26	t.	t.	PROPN
dti-2277	374	27	,	,	PUNCT
dti-2277	374	28	yamaguchi	yamaguchi	PROPN
dti-2277	374	29	,	,	PUNCT
dti-2277	374	30	o.	o.	PROPN
dti-2277	374	31	,	,	PUNCT
dti-2277	374	32	otsu	otsu	PROPN
dti-2277	374	33	,	,	PUNCT
dti-2277	374	34	k.	k.	PROPN
dti-2277	374	35	,	,	PUNCT
dti-2277	374	36	yamagata	yamagata	PROPN
dti-2277	374	37	,	,	PUNCT
dti-2277	374	38	h.	h.	PROPN
dti-2277	374	39	,	,	PUNCT
dti-2277	374	40	inohara	inohara	PROPN
dti-2277	374	41	,	,	PUNCT
dti-2277	374	42	h.	h.	PROPN
dti-2277	374	43	,	,	PUNCT
dti-2277	374	44	kubo	kubo	PROPN
dti-2277	374	45	,	,	PUNCT
dti-2277	374	46	t.	t.	PROPN
dti-2277	374	47	and	and	CCONJ
dti-2277	374	48	tsujimoto	tsujimoto	NOUN
dti-2277	374	49	,	,	PUNCT
dti-2277	374	50	y.	y.	PROPN
dti-2277	374	51	2005	2005	NUM
dti-2277	374	52	.	.	PUNCT
dti-2277	375	1	cyclophilin	cyclophilin	PROPN
dti-2277	375	2	d	d	PROPN
dti-2277	375	3	-	-	PUNCT
dti-2277	375	4	dependent	dependent	ADJ
dti-2277	375	5	mitochondrial	mitochondrial	ADJ
dti-2277	375	6	permeability	permeability	NOUN
dti-2277	375	7	transition	transition	NOUN
dti-2277	375	8	regulates	regulate	VERB
dti-2277	375	9	some	some	DET
dti-2277	375	10	necrotic	necrotic	ADJ
dti-2277	375	11	but	but	CCONJ
dti-2277	375	12	not	not	PART
dti-2277	375	13	apoptotic	apoptotic	ADJ
dti-2277	375	14	cell	cell	NOUN
dti-2277	375	15	death	death	NOUN
dti-2277	375	16	.	.	PUNCT
dti-2277	376	1	nature	nature	NOUN
dti-2277	376	2	,	,	PUNCT
dti-2277	376	3	434:652–658	434:652–658	NUM
dti-2277	376	4	.	.	PUNCT
dti-2277	377	1	nestel	nestel	NOUN
dti-2277	377	2	,	,	PUNCT
dti-2277	377	3	f.	f.	PROPN
dti-2277	377	4	p.	p.	PROPN
dti-2277	377	5	,	,	PUNCT
dti-2277	377	6	colwill	colwill	PROPN
dti-2277	377	7	,	,	PUNCT
dti-2277	377	8	k.	k.	PROPN
dti-2277	377	9	,	,	PUNCT
dti-2277	377	10	harper	harper	PROPN
dti-2277	377	11	,	,	PUNCT
dti-2277	377	12	s.	s.	PROPN
dti-2277	377	13	,	,	PUNCT
dti-2277	377	14	pawson	pawson	PROPN
dti-2277	377	15	,	,	PUNCT
dti-2277	377	16	t.	t.	PROPN
dti-2277	377	17	and	and	CCONJ
dti-2277	377	18	anderson	anderson	PROPN
dti-2277	377	19	,	,	PUNCT
dti-2277	377	20	s.	s.	PROPN
dti-2277	377	21	k.	k.	PROPN
dti-2277	377	22	1996	1996	NUM
dti-2277	377	23	.	.	PUNCT
dti-2277	378	1	rs	rs	PROPN
dti-2277	378	2	cyclophilins	cyclophilin	NOUN
dti-2277	378	3	:	:	PUNCT
dti-2277	378	4	identifi	identifi	PROPN
dti-2277	378	5	cation	cation	NOUN
dti-2277	378	6	of	of	ADP
dti-2277	378	7	an	an	DET
dti-2277	378	8	nk	nk	PROPN
dti-2277	378	9	-	-	PUNCT
dti-2277	378	10	tr1	tr1	NOUN
dti-2277	378	11	-	-	PUNCT
dti-2277	378	12	related	relate	VERB
dti-2277	378	13	cyclophilin	cyclophilin	PROPN
dti-2277	378	14	.	.	PUNCT
dti-2277	379	1	gene	gene	NOUN
dti-2277	379	2	.	.	PUNCT
dti-2277	379	3	,	,	PUNCT
dti-2277	379	4	180:151–155	180:151–155	NUM
dti-2277	379	5	.	.	PUNCT
dti-2277	380	1	obata	obata	NOUN
dti-2277	380	2	,	,	PUNCT
dti-2277	380	3	y.	y.	PROPN
dti-2277	380	4	,	,	PUNCT
dti-2277	380	5	yamamoto	yamamoto	PROPN
dti-2277	380	6	,	,	PUNCT
dti-2277	380	7	k.	k.	PROPN
dti-2277	380	8	,	,	PUNCT
dti-2277	380	9	miyazaki	miyazaki	PROPN
dti-2277	380	10	,	,	PUNCT
dti-2277	380	11	m.	m.	NOUN
dti-2277	380	12	,	,	PUNCT
dti-2277	380	13	shimotohno	shimotohno	NOUN
dti-2277	380	14	,	,	PUNCT
dti-2277	380	15	k.	k.	PROPN
dti-2277	380	16	,	,	PUNCT
dti-2277	380	17	kohno	kohno	PROPN
dti-2277	380	18	,	,	PUNCT
dti-2277	380	19	s.	s.	PROPN
dti-2277	380	20	and	and	CCONJ
dti-2277	380	21	matsuyama	matsuyama	PROPN
dti-2277	380	22	,	,	PUNCT
dti-2277	380	23	t.	t.	PROPN
dti-2277	380	24	2005	2005	NUM
dti-2277	380	25	.	.	PUNCT
dti-2277	381	1	role	role	NOUN
dti-2277	381	2	of	of	ADP
dti-2277	381	3	cyclophilin	cyclophilin	PROPN
dti-2277	381	4	b	b	PROPN
dti-2277	381	5	in	in	ADP
dti-2277	381	6	activation	activation	NOUN
dti-2277	381	7	of	of	ADP
dti-2277	381	8	interferon	interferon	ADJ
dti-2277	381	9	regulatory	regulatory	ADJ
dti-2277	381	10	factor-3	factor-3	PROPN
dti-2277	381	11	.	.	PUNCT
dti-2277	382	1	j.	j.	PROPN
dti-2277	382	2	biol	biol	PROPN
dti-2277	382	3	.	.	PUNCT
dti-2277	383	1	chem	chem	PROPN
dti-2277	383	2	.	.	PUNCT
dti-2277	383	3	,	,	PUNCT
dti-2277	383	4	280:18355–18360	280:18355–18360	X
dti-2277	383	5	.	.	PUNCT
dti-2277	384	1	ott	ott	PROPN
dti-2277	384	2	,	,	PUNCT
dti-2277	384	3	d.e	d.e	PROPN
dti-2277	384	4	.	.	PROPN
dti-2277	384	5	,	,	PUNCT
dti-2277	384	6	coren	coren	PROPN
dti-2277	384	7	,	,	PUNCT
dti-2277	384	8	l.v	l.v	PROPN
dti-2277	384	9	.	.	PROPN
dti-2277	384	10	,	,	PUNCT
dti-2277	384	11	johnson	johnson	PROPN
dti-2277	384	12	,	,	PUNCT
dti-2277	384	13	d.g	d.g	PROPN
dti-2277	384	14	.	.	PROPN
dti-2277	384	15	,	,	PUNCT
dti-2277	384	16	sowder	sowder	NOUN
dti-2277	384	17	,	,	PUNCT
dti-2277	384	18	r.c	r.c	PROPN
dti-2277	384	19	.	.	PROPN
dti-2277	384	20	,	,	PUNCT
dti-2277	384	21	2nd	2nd	PROPN
dti-2277	384	22	,	,	PUNCT
dti-2277	384	23	arthur	arthur	PROPN
dti-2277	384	24	,	,	PUNCT
dti-2277	384	25	l.o	l.o	PROPN
dti-2277	384	26	.	.	PROPN
dti-2277	384	27	and	and	CCONJ
dti-2277	384	28	henderson	henderson	PROPN
dti-2277	384	29	,	,	PUNCT
dti-2277	384	30	l.e	l.e	PROPN
dti-2277	384	31	.	.	PROPN
dti-2277	384	32	1995	1995	NUM
dti-2277	384	33	.	.	PUNCT
dti-2277	385	1	analysis	analysis	NOUN
dti-2277	385	2	and	and	CCONJ
dti-2277	385	3	localization	localization	NOUN
dti-2277	385	4	of	of	ADP
dti-2277	385	5	cyclophilin	cyclophilin	PROPN
dti-2277	385	6	a	a	DET
dti-2277	385	7	found	find	VERB
dti-2277	385	8	in	in	ADP
dti-2277	385	9	the	the	DET
dti-2277	385	10	virions	virion	NOUN
dti-2277	385	11	of	of	ADP
dti-2277	385	12	human	human	ADJ
dti-2277	385	13	immunodefi	immunodefi	PROPN
dti-2277	385	14	ciency	ciency	NOUN
dti-2277	385	15	virus	virus	NOUN
dti-2277	385	16	type	type	NOUN
dti-2277	385	17	1	1	NUM
dti-2277	385	18	mn	mn	PROPN
dti-2277	385	19	strain	strain	NOUN
dti-2277	385	20	.	.	PUNCT
dti-2277	386	1	aids	aids	PROPN
dti-2277	386	2	.	.	PUNCT
dti-2277	387	1	res	re	NOUN
dti-2277	387	2	.	.	PUNCT
dti-2277	387	3	hum	hum	PROPN
dti-2277	387	4	.	.	PUNCT
dti-2277	388	1	retroviruses	retrovirus	NOUN
dti-2277	388	2	11:1003–1006	11:1003–1006	NUM
dti-2277	388	3	.	.	PUNCT
dti-2277	389	1	owens	owens	PROPN
dti-2277	389	2	-	-	PUNCT
dti-2277	389	3	grillo	grillo	PROPN
dti-2277	389	4	,	,	PUNCT
dti-2277	389	5	j.k	j.k	PROPN
dti-2277	389	6	.	.	PROPN
dti-2277	389	7	,	,	PUNCT
dti-2277	389	8	hoffmann	hoffmann	PROPN
dti-2277	389	9	,	,	PUNCT
dti-2277	389	10	k.	k.	PROPN
dti-2277	389	11	,	,	PUNCT
dti-2277	389	12	hutchison	hutchison	PROPN
dti-2277	389	13	,	,	PUNCT
dti-2277	389	14	k.a	k.a	PROPN
dti-2277	389	15	.	.	PROPN
dti-2277	389	16	,	,	PUNCT
dti-2277	389	17	yem	yem	PROPN
dti-2277	389	18	,	,	PUNCT
dti-2277	389	19	a.w	a.w	PROPN
dti-2277	389	20	.	.	PROPN
dti-2277	389	21	,	,	PUNCT
dti-2277	389	22	deibel	deibel	PROPN
dti-2277	389	23	,	,	PUNCT
dti-2277	389	24	m.r	m.r	PROPN
dti-2277	389	25	.	.	PROPN
dti-2277	389	26	jr	jr	PROPN
dti-2277	389	27	.	.	PROPN
dti-2277	389	28	,	,	PUNCT
dti-2277	389	29	handschumacher	handschumacher	PROPN
dti-2277	389	30	,	,	PUNCT
dti-2277	389	31	r.	r.	PROPN
dti-2277	389	32	e.	e.	PROPN
dti-2277	389	33	and	and	CCONJ
dti-2277	389	34	pratt	pratt	PROPN
dti-2277	389	35	,	,	PUNCT
dti-2277	389	36	w.b	w.b	PROPN
dti-2277	389	37	.	.	PROPN
dti-2277	389	38	1995	1995	NUM
dti-2277	389	39	.	.	PUNCT
dti-2277	390	1	the	the	DET
dti-2277	390	2	cyclosporin	cyclosporin	NOUN
dti-2277	390	3	a	a	ADV
dti-2277	390	4	-	-	PUNCT
dti-2277	390	5	binding	bind	VERB
dti-2277	390	6	immunophilin	immunophilin	NOUN
dti-2277	390	7	cyp-40	cyp-40	ADP
dti-2277	390	8	and	and	CCONJ
dti-2277	390	9	the	the	DET
dti-2277	390	10	fk506	fk506	NOUN
dti-2277	390	11	-	-	PUNCT
dti-2277	390	12	binding	bind	VERB
dti-2277	390	13	immunophilin	immunophilin	NOUN
dti-2277	390	14	hsp56	hsp56	NOUN
dti-2277	390	15	bind	bind	NOUN
dti-2277	390	16	to	to	ADP
dti-2277	390	17	a	a	DET
dti-2277	390	18	common	common	ADJ
dti-2277	390	19	site	site	NOUN
dti-2277	390	20	on	on	ADP
dti-2277	390	21	hsp90	hsp90	NOUN
dti-2277	390	22	and	and	CCONJ
dti-2277	390	23	exist	exist	VERB
dti-2277	390	24	in	in	ADP
dti-2277	390	25	independent	independent	ADJ
dti-2277	390	26	cytosolic	cytosolic	ADJ
dti-2277	390	27	heterocomplexes	heterocomplexe	NOUN
dti-2277	390	28	with	with	ADP
dti-2277	390	29	the	the	DET
dti-2277	390	30	untransformed	untransformed	ADJ
dti-2277	390	31	glucocorticoid	glucocorticoid	ADJ
dti-2277	390	32	receptor	receptor	NOUN
dti-2277	390	33	.	.	PUNCT
dti-2277	391	1	j.	j.	PROPN
dti-2277	391	2	biol	biol	PROPN
dti-2277	391	3	.	.	PUNCT
dti-2277	392	1	chem	chem	PROPN
dti-2277	392	2	.	.	PUNCT
dti-2277	392	3	,	,	PUNCT
dti-2277	393	1	270:20479–20484	270:20479–20484	PROPN
dti-2277	393	2	.	.	PUNCT
dti-2277	393	3	ozaki	ozaki	PROPN
dti-2277	393	4	,	,	PUNCT
dti-2277	393	5	k.	k.	PROPN
dti-2277	393	6	,	,	PUNCT
dti-2277	393	7	fujiwara	fujiwara	PROPN
dti-2277	393	8	,	,	PUNCT
dti-2277	393	9	t.	t.	PROPN
dti-2277	393	10	,	,	PUNCT
dti-2277	393	11	kawai	kawai	PROPN
dti-2277	393	12	,	,	PUNCT
dti-2277	393	13	a.	a.	PROPN
dti-2277	393	14	,	,	PUNCT
dti-2277	393	15	shimizu	shimizu	PROPN
dti-2277	393	16	,	,	PUNCT
dti-2277	393	17	f.	f.	PROPN
dti-2277	393	18	,	,	PUNCT
dti-2277	393	19	takami	takami	PROPN
dti-2277	393	20	,	,	PUNCT
dti-2277	393	21	s.	s.	PROPN
dti-2277	393	22	,	,	PUNCT
dti-2277	393	23	okuno	okuno	PROPN
dti-2277	393	24	,	,	PUNCT
dti-2277	393	25	s.	s.	PROPN
dti-2277	393	26	,	,	PUNCT
dti-2277	393	27	takeda	takeda	PROPN
dti-2277	393	28	,	,	PUNCT
dti-2277	393	29	s.	s.	PROPN
dti-2277	393	30	,	,	PUNCT
dti-2277	393	31	shimada	shimada	PROPN
dti-2277	393	32	,	,	PUNCT
dti-2277	393	33	y.	y.	PROPN
dti-2277	393	34	,	,	PUNCT
dti-2277	393	35	nagata	nagata	PROPN
dti-2277	393	36	,	,	PUNCT
dti-2277	393	37	m.	m.	NOUN
dti-2277	393	38	and	and	CCONJ
dti-2277	393	39	watanabe	watanabe	PROPN
dti-2277	393	40	,	,	PUNCT
dti-2277	393	41	t.	t.	PROPN
dti-2277	393	42	et	et	PROPN
dti-2277	393	43	al	al	PROPN
dti-2277	393	44	.	.	PROPN
dti-2277	393	45	1996	1996	NUM
dti-2277	393	46	.	.	PUNCT
dti-2277	394	1	cloning	cloning	NOUN
dti-2277	394	2	,	,	PUNCT
dti-2277	394	3	expression	expression	NOUN
dti-2277	394	4	and	and	CCONJ
dti-2277	394	5	chromosomal	chromosomal	ADJ
dti-2277	394	6	mapping	mapping	NOUN
dti-2277	394	7	of	of	ADP
dti-2277	394	8	a	a	DET
dti-2277	394	9	novel	novel	ADJ
dti-2277	394	10	cyclophilin	cyclophilin	ADV
dti-2277	394	11	-	-	PUNCT
dti-2277	394	12	related	relate	VERB
dti-2277	394	13	gene	gene	NOUN
dti-2277	394	14	(	(	PUNCT
dti-2277	394	15	ppil1	ppil1	NOUN
dti-2277	394	16	)	)	PUNCT
dti-2277	394	17	from	from	ADP
dti-2277	394	18	human	human	ADJ
dti-2277	394	19	fetal	fetal	ADJ
dti-2277	394	20	brain	brain	NOUN
dti-2277	394	21	.	.	PUNCT
dti-2277	395	1	cytogenet	cytogenet	NOUN
dti-2277	395	2	.	.	PUNCT
dti-2277	396	1	cell	cell	NOUN
dti-2277	396	2	.	.	PUNCT
dti-2277	397	1	genet	genet	NOUN
dti-2277	397	2	.	.	PUNCT
dti-2277	397	3	,	,	PUNCT
dti-2277	398	1	72:242–245	72:242–245	NUM
dti-2277	398	2	.	.	PUNCT
dti-2277	398	3	paeshuyse	paeshuyse	NOUN
dti-2277	398	4	,	,	PUNCT
dti-2277	398	5	j.	j.	PROPN
dti-2277	398	6	,	,	PUNCT
dti-2277	398	7	kaul	kaul	PROPN
dti-2277	398	8	,	,	PUNCT
dti-2277	398	9	a.	a.	NOUN
dti-2277	398	10	,	,	PUNCT
dti-2277	398	11	de	de	X
dti-2277	398	12	clercq	clercq	PROPN
dti-2277	398	13	,	,	PUNCT
dti-2277	398	14	e.	e.	PROPN
dti-2277	398	15	,	,	PUNCT
dti-2277	398	16	rosenwirth	rosenwirth	PROPN
dti-2277	398	17	,	,	PUNCT
dti-2277	398	18	b.	b.	PROPN
dti-2277	398	19	,	,	PUNCT
dti-2277	398	20	dumont	dumont	PROPN
dti-2277	398	21	,	,	PUNCT
dti-2277	398	22	j.m	j.m	AUX
dti-2277	398	23	.	.	PROPN
dti-2277	398	24	,	,	PUNCT
dti-2277	398	25	scalfaro	scalfaro	VERB
dti-2277	398	26	,	,	PUNCT
dti-2277	398	27	p.	p.	NOUN
dti-2277	398	28	,	,	PUNCT
dti-2277	398	29	bartenschlager	bartenschlager	NOUN
dti-2277	398	30	,	,	PUNCT
dti-2277	398	31	r.	r.	PROPN
dti-2277	398	32	and	and	CCONJ
dti-2277	398	33	neyts	neyts	PROPN
dti-2277	398	34	,	,	PUNCT
dti-2277	398	35	j.	j.	PROPN
dti-2277	398	36	2006	2006	NUM
dti-2277	398	37	.	.	PUNCT
dti-2277	399	1	the	the	DET
dti-2277	399	2	non	non	ADJ
dti-2277	399	3	-	-	ADJ
dti-2277	399	4	immunosuppressive	immunosuppressive	ADJ
dti-2277	399	5	cyclosporin	cyclosporin	NOUN
dti-2277	399	6	debio-025	debio-025	NOUN
dti-2277	399	7	is	be	AUX
dti-2277	399	8	a	a	DET
dti-2277	399	9	potent	potent	ADJ
dti-2277	399	10	inhibitor	inhibitor	NOUN
dti-2277	399	11	of	of	ADP
dti-2277	399	12	hepatitis	hepatitis	PROPN
dti-2277	399	13	c	c	PROPN
dti-2277	399	14	virus	virus	NOUN
dti-2277	399	15	replication	replication	NOUN
dti-2277	399	16	in	in	ADP
dti-2277	399	17	vitro	vitro	X
dti-2277	399	18	.	.	PUNCT
dti-2277	400	1	hepatology	hepatology	NOUN
dti-2277	400	2	,	,	PUNCT
dti-2277	400	3	43:761–770	43:761–770	PROPN
dti-2277	400	4	.	.	PUNCT
dti-2277	401	1	poynard	poynard	PROPN
dti-2277	401	2	,	,	PUNCT
dti-2277	401	3	t.	t.	PROPN
dti-2277	401	4	,	,	PUNCT
dti-2277	401	5	yuen	yuen	PROPN
dti-2277	401	6	,	,	PUNCT
dti-2277	401	7	m.f	m.f	PROPN
dti-2277	401	8	.	.	PROPN
dti-2277	401	9	,	,	PUNCT
dti-2277	401	10	ratziu	ratziu	NOUN
dti-2277	401	11	,	,	PUNCT
dti-2277	401	12	v.	v.	PROPN
dti-2277	401	13	and	and	CCONJ
dti-2277	401	14	lai	lai	PROPN
dti-2277	401	15	,	,	PUNCT
dti-2277	401	16	c.l	c.l	PROPN
dti-2277	401	17	.	.	PROPN
dti-2277	401	18	2003	2003	NUM
dti-2277	401	19	.	.	PUNCT
dti-2277	402	1	viral	viral	ADJ
dti-2277	402	2	hepatitis	hepatitis	PROPN
dti-2277	402	3	c.	c.	PROPN
dti-2277	402	4	lancet	lancet	PROPN
dti-2277	402	5	.	.	PUNCT
dti-2277	403	1	,	,	PUNCT
dti-2277	403	2	362:2095–2100	362:2095–2100	X
dti-2277	403	3	.	.	PUNCT
dti-2277	404	1	price	price	NOUN
dti-2277	404	2	,	,	PUNCT
dti-2277	404	3	e.r	e.r	PROPN
dti-2277	404	4	.	.	PROPN
dti-2277	404	5	,	,	PUNCT
dti-2277	404	6	zydowsky	zydowsky	PROPN
dti-2277	404	7	,	,	PUNCT
dti-2277	404	8	l.d	l.d	PROPN
dti-2277	404	9	.	.	PROPN
dti-2277	404	10	,	,	PUNCT
dti-2277	404	11	jin	jin	PROPN
dti-2277	404	12	,	,	PUNCT
dti-2277	404	13	m.j	m.j	PROPN
dti-2277	404	14	.	.	PROPN
dti-2277	404	15	,	,	PUNCT
dti-2277	404	16	baker	baker	PROPN
dti-2277	404	17	,	,	PUNCT
dti-2277	404	18	c.h	c.h	PROPN
dti-2277	404	19	.	.	PROPN
dti-2277	404	20	,	,	PUNCT
dti-2277	404	21	mckeon	mckeon	PROPN
dti-2277	404	22	,	,	PUNCT
dti-2277	404	23	f.d	f.d	PROPN
dti-2277	404	24	.	.	PROPN
dti-2277	404	25	and	and	CCONJ
dti-2277	404	26	walsh	walsh	PROPN
dti-2277	404	27	,	,	PUNCT
dti-2277	404	28	c.t	c.t	PROPN
dti-2277	404	29	.	.	PROPN
dti-2277	404	30	1991	1991	NUM
dti-2277	404	31	.	.	PUNCT
dti-2277	405	1	human	human	ADJ
dti-2277	405	2	cyclophilin	cyclophilin	PROPN
dti-2277	405	3	b	b	PROPN
dti-2277	405	4	:	:	PUNCT
dti-2277	405	5	a	a	DET
dti-2277	405	6	second	second	ADJ
dti-2277	405	7	cyclophilin	cyclophilin	PROPN
dti-2277	405	8	gene	gene	NOUN
dti-2277	405	9	encodes	encode	VERB
dti-2277	405	10	a	a	DET
dti-2277	405	11	peptidyl	peptidyl	NOUN
dti-2277	405	12	-	-	PUNCT
dti-2277	405	13	prolyl	prolyl	NOUN
dti-2277	405	14	isomerase	isomerase	NOUN
dti-2277	405	15	with	with	ADP
dti-2277	405	16	a	a	DET
dti-2277	405	17	signal	signal	ADJ
dti-2277	405	18	sequence	sequence	NOUN
dti-2277	405	19	.	.	PUNCT
dti-2277	406	1	proc	proc	PROPN
dti-2277	406	2	.	.	PUNCT
dti-2277	407	1	natl	natl	PROPN
dti-2277	407	2	.	.	PUNCT
dti-2277	408	1	acad	acad	PROPN
dti-2277	408	2	.	.	PUNCT
dti-2277	409	1	sci	sci	PROPN
dti-2277	409	2	.	.	PUNCT
dti-2277	409	3	u.s.a	u.s.a	PROPN
dti-2277	409	4	.	.	PROPN
dti-2277	409	5	,	,	PUNCT
dti-2277	409	6	88:1903–1907	88:1903–1907	PROPN
dti-2277	409	7	.	.	PUNCT
dti-2277	410	1	pushkarsky	pushkarsky	ADJ
dti-2277	410	2	,	,	PUNCT
dti-2277	410	3	t.	t.	PROPN
dti-2277	410	4	,	,	PUNCT
dti-2277	410	5	zybarth	zybarth	PROPN
dti-2277	410	6	,	,	PUNCT
dti-2277	410	7	g.	g.	PROPN
dti-2277	410	8	,	,	PUNCT
dti-2277	410	9	dubrovsky	dubrovsky	PROPN
dti-2277	410	10	,	,	PUNCT
dti-2277	410	11	l.	l.	PROPN
dti-2277	410	12	,	,	PUNCT
dti-2277	410	13	yurchenko	yurchenko	PROPN
dti-2277	410	14	,	,	PUNCT
dti-2277	410	15	v.	v.	PROPN
dti-2277	410	16	,	,	PUNCT
dti-2277	410	17	tang	tang	PROPN
dti-2277	410	18	,	,	PUNCT
dti-2277	410	19	h.	h.	PROPN
dti-2277	410	20	,	,	PUNCT
dti-2277	410	21	guo	guo	PROPN
dti-2277	410	22	,	,	PUNCT
dti-2277	410	23	h.	h.	PROPN
dti-2277	410	24	,	,	PUNCT
dti-2277	410	25	toole	toole	PROPN
dti-2277	410	26	,	,	PUNCT
dti-2277	410	27	b.	b.	PROPN
dti-2277	410	28	,	,	PUNCT
dti-2277	410	29	sherry	sherry	PROPN
dti-2277	410	30	,	,	PUNCT
dti-2277	410	31	b.	b.	PROPN
dti-2277	410	32	and	and	CCONJ
dti-2277	410	33	bukrinsky	bukrinsky	PROPN
dti-2277	410	34	,	,	PUNCT
dti-2277	410	35	m.	m.	NOUN
dti-2277	410	36	2001	2001	NUM
dti-2277	410	37	.	.	PUNCT
dti-2277	411	1	cd147	cd147	PROPN
dti-2277	411	2	facilitates	facilitate	VERB
dti-2277	411	3	hiv-1	hiv-1	PART
dti-2277	411	4	infection	infection	NOUN
dti-2277	411	5	by	by	ADP
dti-2277	411	6	interacting	interact	VERB
dti-2277	411	7	with	with	ADP
dti-2277	411	8	virus	virus	NOUN
dti-2277	411	9	-	-	PUNCT
dti-2277	411	10	associated	associate	VERB
dti-2277	411	11	cyclophilin	cyclophilin	PROPN
dti-2277	411	12	a.	a.	NOUN
dti-2277	411	13	proc	proc	PROPN
dti-2277	411	14	.	.	PUNCT
dti-2277	412	1	natl	natl	PROPN
dti-2277	412	2	.	.	PUNCT
dti-2277	413	1	acad	acad	PROPN
dti-2277	413	2	.	.	PUNCT
dti-2277	414	1	sci	sci	PROPN
dti-2277	414	2	.	.	PUNCT
dti-2277	414	3	u.s.a	u.s.a	PROPN
dti-2277	414	4	.	.	PROPN
dti-2277	414	5	,	,	PUNCT
dti-2277	414	6	98:6360–6365	98:6360–6365	X
dti-2277	414	7	.	.	PUNCT
dti-2277	415	1	ratajczak	ratajczak	PROPN
dti-2277	415	2	,	,	PUNCT
dti-2277	415	3	t.	t.	PROPN
dti-2277	415	4	,	,	PUNCT
dti-2277	415	5	carrello	carrello	PROPN
dti-2277	415	6	,	,	PUNCT
dti-2277	415	7	a.	a.	NOUN
dti-2277	415	8	,	,	PUNCT
dti-2277	415	9	mark	mark	NOUN
dti-2277	415	10	,	,	PUNCT
dti-2277	415	11	p.j	p.j	PROPN
dti-2277	415	12	.	.	PROPN
dti-2277	415	13	,	,	PUNCT
dti-2277	415	14	warner	warner	PROPN
dti-2277	415	15	,	,	PUNCT
dti-2277	415	16	b.j	b.j	PROPN
dti-2277	415	17	.	.	PROPN
dti-2277	415	18	,	,	PUNCT
dti-2277	415	19	simpson	simpson	PROPN
dti-2277	415	20	,	,	PUNCT
dti-2277	415	21	r.j	r.j	PROPN
dti-2277	415	22	.	.	PROPN
dti-2277	415	23	,	,	PUNCT
dti-2277	415	24	moritz	moritz	PROPN
dti-2277	415	25	,	,	PUNCT
dti-2277	415	26	r.l	r.l	PROPN
dti-2277	415	27	.	.	PROPN
dti-2277	415	28	and	and	CCONJ
dti-2277	415	29	house	house	PROPN
dti-2277	415	30	,	,	PUNCT
dti-2277	415	31	a.k	a.k	PROPN
dti-2277	415	32	.	.	PROPN
dti-2277	415	33	1993	1993	NUM
dti-2277	415	34	.	.	PUNCT
dti-2277	416	1	the	the	DET
dti-2277	416	2	cyclophilin	cyclophilin	PROPN
dti-2277	416	3	component	component	NOUN
dti-2277	416	4	of	of	ADP
dti-2277	416	5	the	the	DET
dti-2277	416	6	unactivated	unactivated	ADJ
dti-2277	416	7	estrogen	estrogen	NOUN
dti-2277	416	8	receptor	receptor	NOUN
dti-2277	416	9	contains	contain	VERB
dti-2277	416	10	a	a	DET
dti-2277	416	11	tetratricopeptide	tetratricopeptide	ADJ
dti-2277	416	12	repeat	repeat	NOUN
dti-2277	416	13	domain	domain	NOUN
dti-2277	416	14	and	and	CCONJ
dti-2277	416	15	shares	share	VERB
dti-2277	416	16	identity	identity	NOUN
dti-2277	416	17	with	with	ADP
dti-2277	416	18	p59	p59	NOUN
dti-2277	416	19	(	(	PUNCT
dti-2277	416	20	fkbp59	fkbp59	NOUN
dti-2277	416	21	)	)	PUNCT
dti-2277	416	22	.	.	PUNCT
dti-2277	417	1	j.	j.	PROPN
dti-2277	417	2	biol	biol	PROPN
dti-2277	417	3	.	.	PUNCT
dti-2277	418	1	chem	chem	PROPN
dti-2277	418	2	.	.	PUNCT
dti-2277	418	3	,	,	PUNCT
dti-2277	419	1	268:13187–13192	268:13187–13192	X
dti-2277	419	2	.	.	PUNCT
dti-2277	420	1	rosen	rosen	PROPN
dti-2277	420	2	,	,	PUNCT
dti-2277	420	3	m.k	m.k	PROPN
dti-2277	420	4	.	.	PROPN
dti-2277	420	5	,	,	PUNCT
dti-2277	420	6	standaert	standaert	PROPN
dti-2277	420	7	,	,	PUNCT
dti-2277	420	8	r.f	r.f	PROPN
dti-2277	420	9	.	.	PROPN
dti-2277	420	10	,	,	PUNCT
dti-2277	420	11	galat	galat	PROPN
dti-2277	420	12	,	,	PUNCT
dti-2277	420	13	a.	a.	NOUN
dti-2277	420	14	,	,	PUNCT
dti-2277	420	15	nakatsuka	nakatsuka	PROPN
dti-2277	420	16	,	,	PUNCT
dti-2277	420	17	m.	m.	NOUN
dti-2277	420	18	and	and	CCONJ
dti-2277	420	19	schreiber	schreiber	PROPN
dti-2277	420	20	,	,	PUNCT
dti-2277	420	21	s.	s.	PROPN
dti-2277	420	22	l.	l.	PROPN
dti-2277	420	23	1990	1990	NUM
dti-2277	420	24	.	.	PUNCT
dti-2277	421	1	inhibition	inhibition	NOUN
dti-2277	421	2	of	of	ADP
dti-2277	421	3	fkbp	fkbp	ADJ
dti-2277	421	4	rotamase	rotamase	NOUN
dti-2277	421	5	activity	activity	NOUN
dti-2277	421	6	by	by	ADP
dti-2277	421	7	immunosuppressant	immunosuppressant	ADJ
dti-2277	421	8	fk506	fk506	PROPN
dti-2277	421	9	:	:	PUNCT
dti-2277	421	10	twisted	twisted	ADJ
dti-2277	421	11	amide	amide	NOUN
dti-2277	421	12	surrogate	surrogate	NOUN
dti-2277	421	13	.	.	PUNCT
dti-2277	422	1	science	science	NOUN
dti-2277	422	2	,	,	PUNCT
dti-2277	422	3	248:863–866	248:863–866	PROPN
dti-2277	422	4	.	.	PUNCT
dti-2277	422	5	rosenwirth	rosenwirth	PROPN
dti-2277	422	6	,	,	PUNCT
dti-2277	422	7	b.	b.	PROPN
dti-2277	422	8	,	,	PUNCT
dti-2277	422	9	billich	billich	PROPN
dti-2277	422	10	,	,	PUNCT
dti-2277	422	11	a.	a.	PROPN
dti-2277	422	12	,	,	PUNCT
dti-2277	422	13	datema	datema	PROPN
dti-2277	422	14	,	,	PUNCT
dti-2277	422	15	r.	r.	PROPN
dti-2277	422	16	,	,	PUNCT
dti-2277	422	17	donatsch	donatsch	VERB
dti-2277	422	18	,	,	PUNCT
dti-2277	422	19	p.	p.	NOUN
dti-2277	422	20	,	,	PUNCT
dti-2277	422	21	hammerschmid	hammerschmid	PROPN
dti-2277	422	22	,	,	PUNCT
dti-2277	422	23	f.	f.	PROPN
dti-2277	422	24	,	,	PUNCT
dti-2277	422	25	harrison	harrison	PROPN
dti-2277	422	26	,	,	PUNCT
dti-2277	422	27	r.	r.	PROPN
dti-2277	422	28	,	,	PUNCT
dti-2277	422	29	hiestand	hiestand	NOUN
dti-2277	422	30	,	,	PUNCT
dti-2277	422	31	p.	p.	PROPN
dti-2277	422	32	,	,	PUNCT
dti-2277	422	33	jaksche	jaksche	PROPN
dti-2277	422	34	,	,	PUNCT
dti-2277	422	35	h.	h.	PROPN
dti-2277	422	36	,	,	PUNCT
dti-2277	422	37	mayer	mayer	PROPN
dti-2277	422	38	,	,	PUNCT
dti-2277	422	39	p.	p.	NOUN
dti-2277	422	40	and	and	CCONJ
dti-2277	422	41	peichl	peichl	ADJ
dti-2277	422	42	,	,	PUNCT
dti-2277	422	43	p.	p.	NOUN
dti-2277	422	44	et	et	NOUN
dti-2277	423	1	al	al	PROPN
dti-2277	423	2	.	.	PROPN
dti-2277	423	3	1994	1994	NUM
dti-2277	423	4	.	.	PUNCT
dti-2277	424	1	inhibition	inhibition	NOUN
dti-2277	424	2	of	of	ADP
dti-2277	424	3	human	human	ADJ
dti-2277	424	4	immunodefi	immunodefi	PROPN
dti-2277	424	5	ciency	ciency	NOUN
dti-2277	424	6	virus	virus	NOUN
dti-2277	424	7	type	type	NOUN
dti-2277	424	8	1	1	NUM
dti-2277	424	9	replication	replication	NOUN
dti-2277	424	10	by	by	ADP
dti-2277	424	11	sdz	sdz	PROPN
dti-2277	424	12	nim	nim	PROPN
dti-2277	424	13	811	811	NUM
dti-2277	424	14	,	,	PUNCT
dti-2277	424	15	a	a	DET
dti-2277	424	16	nonimmunosuppressive	nonimmunosuppressive	ADJ
dti-2277	424	17	cyclosporine	cyclosporine	ADJ
dti-2277	424	18	analog	analog	NOUN
dti-2277	424	19	.	.	PUNCT
dti-2277	425	1	antimicrob	antimicrob	PROPN
dti-2277	425	2	.	.	PUNCT
dti-2277	426	1	agents	agent	NOUN
dti-2277	426	2	.	.	PUNCT
dti-2277	427	1	chemother	chemother	PROPN
dti-2277	427	2	.	.	PUNCT
dti-2277	428	1	,	,	PUNCT
dti-2277	428	2	38:1763–1772	38:1763–1772	PROPN
dti-2277	428	3	.	.	PUNCT
dti-2277	428	4	rycyzyn	rycyzyn	PROPN
dti-2277	428	5	,	,	PUNCT
dti-2277	428	6	m.a	m.a	PROPN
dti-2277	428	7	.	.	PROPN
dti-2277	428	8	and	and	CCONJ
dti-2277	428	9	clevenger	clevenger	PROPN
dti-2277	428	10	,	,	PUNCT
dti-2277	428	11	c.v	c.v	PROPN
dti-2277	428	12	.	.	PROPN
dti-2277	428	13	2002	2002	NUM
dti-2277	428	14	.	.	PUNCT
dti-2277	429	1	the	the	DET
dti-2277	429	2	intranuclear	intranuclear	NOUN
dti-2277	429	3	prolactin	prolactin	PROPN
dti-2277	429	4	/	/	SYM
dti-2277	429	5	cyclophilin	cyclophilin	PROPN
dti-2277	429	6	b	b	PROPN
dti-2277	429	7	complex	complex	NOUN
dti-2277	429	8	as	as	ADP
dti-2277	429	9	a	a	DET
dti-2277	429	10	transcriptional	transcriptional	ADJ
dti-2277	429	11	inducer	inducer	NOUN
dti-2277	429	12	.	.	PUNCT
dti-2277	430	1	proc	proc	PROPN
dti-2277	430	2	.	.	PUNCT
dti-2277	431	1	natl	natl	PROPN
dti-2277	431	2	.	.	PUNCT
dti-2277	432	1	acad	acad	PROPN
dti-2277	432	2	.	.	PUNCT
dti-2277	433	1	sci	sci	PROPN
dti-2277	433	2	.	.	PUNCT
dti-2277	433	3	u.s.a	u.s.a	PROPN
dti-2277	433	4	.	.	PROPN
dti-2277	433	5	,	,	PUNCT
dti-2277	433	6	99:6790–6795	99:6790–6795	NUM
dti-2277	433	7	.	.	PUNCT
dti-2277	433	8	rycyzyn	rycyzyn	PROPN
dti-2277	433	9	,	,	PUNCT
dti-2277	433	10	m.a	m.a	PROPN
dti-2277	433	11	.	.	PROPN
dti-2277	433	12	,	,	PUNCT
dti-2277	433	13	reilly	reilly	PROPN
dti-2277	433	14	,	,	PUNCT
dti-2277	433	15	s.c	s.c	PROPN
dti-2277	433	16	.	.	PROPN
dti-2277	433	17	,	,	PUNCT
dti-2277	433	18	o’malley	o’malley	PROPN
dti-2277	433	19	,	,	PUNCT
dti-2277	433	20	k.	k.	PROPN
dti-2277	433	21	and	and	CCONJ
dti-2277	433	22	clevenger	clevenger	PROPN
dti-2277	433	23	,	,	PUNCT
dti-2277	433	24	c.v	c.v	PROPN
dti-2277	433	25	.	.	PROPN
dti-2277	433	26	2000	2000	NUM
dti-2277	433	27	.	.	PUNCT
dti-2277	434	1	role	role	NOUN
dti-2277	434	2	of	of	ADP
dti-2277	434	3	cyclophilin	cyclophilin	PROPN
dti-2277	434	4	b	b	PROPN
dti-2277	434	5	in	in	ADP
dti-2277	434	6	prolactin	prolactin	NOUN
dti-2277	434	7	signal	signal	NOUN
dti-2277	434	8	transduction	transduction	NOUN
dti-2277	434	9	and	and	CCONJ
dti-2277	434	10	nuclear	nuclear	ADJ
dti-2277	434	11	retrotranslocation	retrotranslocation	NOUN
dti-2277	434	12	.	.	PUNCT
dti-2277	435	1	mol	mol	PROPN
dti-2277	435	2	.	.	PROPN
dti-2277	435	3	endocrinol	endocrinol	NOUN
dti-2277	435	4	.	.	PUNCT
dti-2277	436	1	14:1175–1186	14:1175–1186	X
dti-2277	436	2	.	.	PUNCT
dti-2277	436	3	saphire	saphire	PROPN
dti-2277	436	4	,	,	PUNCT
dti-2277	436	5	a.c	a.c	PROPN
dti-2277	436	6	.	.	PROPN
dti-2277	436	7	,	,	PUNCT
dti-2277	436	8	bobardt	bobardt	PROPN
dti-2277	436	9	,	,	PUNCT
dti-2277	436	10	m.d	m.d	PROPN
dti-2277	436	11	.	.	PROPN
dti-2277	436	12	and	and	CCONJ
dti-2277	436	13	gallay	gallay	NOUN
dti-2277	436	14	,	,	PUNCT
dti-2277	436	15	p.a	p.a	PROPN
dti-2277	436	16	.	.	PROPN
dti-2277	436	17	1999	1999	NUM
dti-2277	436	18	.	.	PUNCT
dti-2277	437	1	host	host	NOUN
dti-2277	437	2	cyclophilin	cyclophilin	PROPN
dti-2277	437	3	a	a	DET
dti-2277	437	4	mediates	mediate	NOUN
dti-2277	437	5	hiv-1	hiv-1	X
dti-2277	437	6	attachment	attachment	NOUN
dti-2277	437	7	to	to	PART
dti-2277	437	8	target	target	VERB
dti-2277	437	9	cells	cell	NOUN
dti-2277	437	10	via	via	ADP
dti-2277	437	11	heparans	heparans	PROPN
dti-2277	437	12	.	.	PUNCT
dti-2277	437	13	embo	embo	PROPN
dti-2277	437	14	.	.	PUNCT
dti-2277	438	1	j.	j.	PROPN
dti-2277	438	2	18	18	NUM
dti-2277	438	3	:	:	SYM
dti-2277	438	4	6771–6785	6771–6785	NUM
dti-2277	438	5	.	.	PUNCT
dti-2277	438	6	sayah	sayah	NOUN
dti-2277	438	7	,	,	PUNCT
dti-2277	438	8	d.m	d.m	PROPN
dti-2277	438	9	.	.	PROPN
dti-2277	438	10	,	,	PUNCT
dti-2277	438	11	sokolskaja	sokolskaja	PROPN
dti-2277	438	12	,	,	PUNCT
dti-2277	438	13	e.	e.	PROPN
dti-2277	438	14	,	,	PUNCT
dti-2277	438	15	berthoux	berthoux	VERB
dti-2277	438	16	,	,	PUNCT
dti-2277	438	17	l.	l.	NOUN
dti-2277	438	18	and	and	CCONJ
dti-2277	438	19	luban	luban	PROPN
dti-2277	438	20	,	,	PUNCT
dti-2277	438	21	j.	j.	PROPN
dti-2277	438	22	2004	2004	NUM
dti-2277	438	23	.	.	PUNCT
dti-2277	439	1	cyclophilin	cyclophilin	PROPN
dti-2277	439	2	a	a	DET
dti-2277	439	3	retrotransposition	retrotransposition	NOUN
dti-2277	439	4	into	into	ADP
dti-2277	439	5	trim5	trim5	NOUN
dti-2277	439	6	explains	explain	VERB
dti-2277	439	7	owl	owl	VERB
dti-2277	439	8	monkey	monkey	NOUN
dti-2277	439	9	resistance	resistance	NOUN
dti-2277	439	10	to	to	ADP
dti-2277	439	11	hiv-1	hiv-1	X
dti-2277	439	12	.	.	PUNCT
dti-2277	439	13	nature	nature	NOUN
dti-2277	439	14	,	,	PUNCT
dti-2277	439	15	430:569–573	430:569–573	NUM
dti-2277	439	16	.	.	PUNCT
dti-2277	440	1	schreiber	schreiber	PROPN
dti-2277	440	2	,	,	PUNCT
dti-2277	440	3	s.l	s.l	PROPN
dti-2277	440	4	.	.	PROPN
dti-2277	440	5	1991	1991	NUM
dti-2277	440	6	.	.	PUNCT
dti-2277	441	1	chemistry	chemistry	NOUN
dti-2277	441	2	and	and	CCONJ
dti-2277	441	3	biology	biology	NOUN
dti-2277	441	4	of	of	ADP
dti-2277	441	5	the	the	DET
dti-2277	441	6	immunophilins	immunophilin	NOUN
dti-2277	441	7	and	and	CCONJ
dti-2277	441	8	their	their	PRON
dti-2277	441	9	immunosuppressive	immunosuppressive	ADJ
dti-2277	441	10	ligands	ligand	NOUN
dti-2277	441	11	.	.	PUNCT
dti-2277	442	1	science	science	NOUN
dti-2277	442	2	,	,	PUNCT
dti-2277	442	3	251:283–287	251:283–287	NUM
dti-2277	442	4	.	.	PUNCT
dti-2277	443	1	seko	seko	NOUN
dti-2277	443	2	,	,	PUNCT
dti-2277	443	3	y.	y.	PROPN
dti-2277	443	4	,	,	PUNCT
dti-2277	443	5	fujimura	fujimura	PROPN
dti-2277	443	6	,	,	PUNCT
dti-2277	443	7	t.	t.	PROPN
dti-2277	443	8	,	,	PUNCT
dti-2277	443	9	taka	taka	PROPN
dti-2277	443	10	,	,	PUNCT
dti-2277	443	11	h.	h.	PROPN
dti-2277	443	12	,	,	PUNCT
dti-2277	443	13	mineki	mineki	PROPN
dti-2277	443	14	,	,	PUNCT
dti-2277	443	15	r.	r.	PROPN
dti-2277	443	16	,	,	PUNCT
dti-2277	443	17	murayama	murayama	PROPN
dti-2277	443	18	,	,	PUNCT
dti-2277	443	19	k.	k.	PROPN
dti-2277	443	20	and	and	CCONJ
dti-2277	443	21	nagai	nagai	PROPN
dti-2277	443	22	,	,	PUNCT
dti-2277	443	23	r.	r.	PROPN
dti-2277	443	24	2004	2004	NUM
dti-2277	443	25	.	.	PUNCT
dti-2277	444	1	hypoxia	hypoxia	NOUN
dti-2277	444	2	followed	follow	VERB
dti-2277	444	3	by	by	ADP
dti-2277	444	4	reoxygenation	reoxygenation	NOUN
dti-2277	444	5	induces	induce	VERB
dti-2277	444	6	secretion	secretion	NOUN
dti-2277	444	7	of	of	ADP
dti-2277	444	8	cyclophilin	cyclophilin	PROPN
dti-2277	444	9	a	a	PRON
dti-2277	444	10	from	from	ADP
dti-2277	444	11	cultured	cultured	ADJ
dti-2277	444	12	rat	rat	NOUN
dti-2277	444	13	cardiac	cardiac	ADJ
dti-2277	444	14	myocytes	myocyte	NOUN
dti-2277	444	15	.	.	PUNCT
dti-2277	445	1	biochem	biochem	PROPN
dti-2277	445	2	.	.	PUNCT
dti-2277	446	1	biophys	biophy	NOUN
dti-2277	446	2	res	res	PROPN
dti-2277	446	3	.	.	PUNCT
dti-2277	447	1	commun	commun	PROPN
dti-2277	447	2	.	.	PROPN
dti-2277	447	3	,	,	PUNCT
dti-2277	447	4	317:162–168	317:162–168	NUM
dti-2277	447	5	.	.	PUNCT
dti-2277	448	1	sherry	sherry	PROPN
dti-2277	448	2	,	,	PUNCT
dti-2277	448	3	b.	b.	PROPN
dti-2277	448	4	,	,	PUNCT
dti-2277	448	5	yarlett	yarlett	PROPN
dti-2277	448	6	,	,	PUNCT
dti-2277	448	7	n.	n.	NOUN
dti-2277	448	8	,	,	PUNCT
dti-2277	448	9	strupp	strupp	PROPN
dti-2277	448	10	,	,	PUNCT
dti-2277	448	11	a.	a.	NOUN
dti-2277	448	12	and	and	CCONJ
dti-2277	448	13	cerami	cerami	PROPN
dti-2277	448	14	,	,	PUNCT
dti-2277	448	15	a.	a.	NOUN
dti-2277	448	16	1992	1992	NUM
dti-2277	448	17	.	.	PUNCT
dti-2277	449	1	identifi	identifi	PROPN
dti-2277	449	2	cation	cation	NOUN
dti-2277	449	3	of	of	ADP
dti-2277	449	4	cyclophilin	cyclophilin	PROPN
dti-2277	449	5	as	as	ADP
dti-2277	449	6	a	a	DET
dti-2277	449	7	proinfl	proinfl	NOUN
dti-2277	449	8	ammatory	ammatory	NOUN
dti-2277	449	9	secretory	secretory	ADJ
dti-2277	449	10	product	product	NOUN
dti-2277	449	11	of	of	ADP
dti-2277	449	12	lipopolysaccharide	lipopolysaccharide	ADV
dti-2277	449	13	-	-	PUNCT
dti-2277	449	14	activated	activate	VERB
dti-2277	449	15	macrophages	macrophage	NOUN
dti-2277	449	16	.	.	PUNCT
dti-2277	450	1	proc	proc	NOUN
dti-2277	450	2	.	.	PUNCT
dti-2277	451	1	natl	natl	PROPN
dti-2277	451	2	.	.	PUNCT
dti-2277	452	1	acad	acad	PROPN
dti-2277	452	2	.	.	PUNCT
dti-2277	453	1	sci	sci	PROPN
dti-2277	453	2	.	.	PUNCT
dti-2277	453	3	u.s.a	u.s.a	PROPN
dti-2277	453	4	.	.	PROPN
dti-2277	453	5	,	,	PUNCT
dti-2277	453	6	89	89	NUM
dti-2277	453	7	:	:	PUNCT
dti-2277	453	8	3511–3515	3511–3515	NUM
dti-2277	453	9	.	.	PUNCT
dti-2277	454	1	sokolskaja	sokolskaja	PROPN
dti-2277	454	2	,	,	PUNCT
dti-2277	454	3	e.	e.	PROPN
dti-2277	454	4	,	,	PUNCT
dti-2277	454	5	sayah	sayah	NOUN
dti-2277	454	6	,	,	PUNCT
dti-2277	454	7	d.m	d.m	PROPN
dti-2277	454	8	.	.	PUNCT
dti-2277	454	9	and	and	CCONJ
dti-2277	454	10	luban	luban	PROPN
dti-2277	454	11	,	,	PUNCT
dti-2277	454	12	j.	j.	PROPN
dti-2277	454	13	2004	2004	NUM
dti-2277	454	14	.	.	PUNCT
dti-2277	455	1	target	target	NOUN
dti-2277	455	2	cell	cell	NOUN
dti-2277	455	3	cyclophilin	cyclophilin	PROPN
dti-2277	455	4	a	a	DET
dti-2277	455	5	modulates	modulate	NOUN
dti-2277	455	6	human	human	ADJ
dti-2277	455	7	immunodefi	immunodefi	PROPN
dti-2277	455	8	ciency	ciency	NOUN
dti-2277	455	9	virus	virus	NOUN
dti-2277	455	10	type	type	NOUN
dti-2277	455	11	1	1	NUM
dti-2277	455	12	infectivity	infectivity	NOUN
dti-2277	455	13	.	.	PUNCT
dti-2277	456	1	j.	j.	PROPN
dti-2277	456	2	virol	virol	PROPN
dti-2277	456	3	.	.	PUNCT
dti-2277	456	4	,	,	PUNCT
dti-2277	456	5	78:12800–12808	78:12800–12808	X
dti-2277	456	6	.	.	PUNCT
dti-2277	456	7	sokolskaja	sokolskaja	PROPN
dti-2277	456	8	,	,	PUNCT
dti-2277	456	9	e.	e.	PROPN
dti-2277	456	10	and	and	CCONJ
dti-2277	456	11	luban	luban	PROPN
dti-2277	456	12	,	,	PUNCT
dti-2277	456	13	j.	j.	PROPN
dti-2277	456	14	2006	2006	NUM
dti-2277	456	15	.	.	PUNCT
dti-2277	457	1	cyclophilin	cyclophilin	PROPN
dti-2277	457	2	a	a	PRON
dti-2277	457	3	,	,	PUNCT
dti-2277	457	4	trim5	trim5	NOUN
dti-2277	457	5	,	,	PUNCT
dti-2277	457	6	and	and	CCONJ
dti-2277	457	7	innate	innate	VERB
dti-2277	457	8	immunity	immunity	NOUN
dti-2277	457	9	to	to	ADP
dti-2277	457	10	hiv-1	hiv-1	X
dti-2277	457	11	.	.	PUNCT
dti-2277	458	1	curr	curr	PROPN
dti-2277	458	2	.	.	PUNCT
dti-2277	459	1	opin	opin	NOUN
dti-2277	459	2	.	.	PUNCT
dti-2277	460	1	microbiol	microbiol	PROPN
dti-2277	460	2	.	.	PUNCT
dti-2277	460	3	,	,	PUNCT
dti-2277	460	4	9:404–408	9:404–408	NUM
dti-2277	460	5	.	.	PUNCT
dti-2277	461	1	steinkasserer	steinkasserer	PROPN
dti-2277	461	2	,	,	PUNCT
dti-2277	461	3	a.	a.	NOUN
dti-2277	461	4	,	,	PUNCT
dti-2277	461	5	harrison	harrison	PROPN
dti-2277	461	6	,	,	PUNCT
dti-2277	461	7	r.	r.	PROPN
dti-2277	461	8	,	,	PUNCT
dti-2277	461	9	billich	billich	PROPN
dti-2277	461	10	,	,	PUNCT
dti-2277	461	11	a.	a.	NOUN
dti-2277	461	12	,	,	PUNCT
dti-2277	461	13	hammerschmid	hammerschmid	PROPN
dti-2277	461	14	,	,	PUNCT
dti-2277	461	15	f.	f.	PROPN
dti-2277	461	16	,	,	PUNCT
dti-2277	461	17	werner	werner	PROPN
dti-2277	461	18	,	,	PUNCT
dti-2277	461	19	g.	g.	PROPN
dti-2277	461	20	,	,	PUNCT
dti-2277	461	21	wolff	wolff	PROPN
dti-2277	461	22	,	,	PUNCT
dti-2277	461	23	b.	b.	PROPN
dti-2277	461	24	,	,	PUNCT
dti-2277	461	25	peichl	peichl	ADJ
dti-2277	461	26	,	,	PUNCT
dti-2277	461	27	p.	p.	NOUN
dti-2277	461	28	,	,	PUNCT
dti-2277	461	29	palfi	palfi	INTJ
dti-2277	461	30	,	,	PUNCT
dti-2277	461	31	g.	g.	PROPN
dti-2277	461	32	,	,	PUNCT
dti-2277	461	33	schnitzel	schnitzel	NOUN
dti-2277	461	34	,	,	PUNCT
dti-2277	461	35	w.	w.	PROPN
dti-2277	461	36	and	and	CCONJ
dti-2277	461	37	mlynar	mlynar	PROPN
dti-2277	461	38	,	,	PUNCT
dti-2277	461	39	e.	e.	PROPN
dti-2277	461	40	et	et	PROPN
dti-2277	461	41	al	al	PROPN
dti-2277	461	42	.	.	PROPN
dti-2277	461	43	1995	1995	NUM
dti-2277	461	44	.	.	PUNCT
dti-2277	462	1	mode	mode	NOUN
dti-2277	462	2	of	of	ADP
dti-2277	462	3	action	action	NOUN
dti-2277	462	4	of	of	ADP
dti-2277	462	5	sdz	sdz	PROPN
dti-2277	462	6	nim	nim	PROPN
dti-2277	462	7	811	811	NUM
dti-2277	462	8	,	,	PUNCT
dti-2277	462	9	a	a	DET
dti-2277	462	10	nonimmunosuppressive	nonimmunosuppressive	ADJ
dti-2277	462	11	cyclosporin	cyclosporin	NOUN
dti-2277	462	12	a	a	DET
dti-2277	462	13	analog	analog	NOUN
dti-2277	462	14	with	with	ADP
dti-2277	462	15	activity	activity	NOUN
dti-2277	462	16	against	against	ADP
dti-2277	462	17	human	human	ADJ
dti-2277	462	18	immunodefi	immunodefi	PROPN
dti-2277	462	19	ciency	ciency	NOUN
dti-2277	462	20	virus	virus	NOUN
dti-2277	462	21	type	type	NOUN
dti-2277	462	22	1	1	NUM
dti-2277	462	23	(	(	PUNCT
dti-2277	462	24	hiv-1	hiv-1	NUM
dti-2277	462	25	):	):	PUNCT
dti-2277	462	26	interference	interference	NOUN
dti-2277	462	27	with	with	ADP
dti-2277	462	28	early	early	ADJ
dti-2277	462	29	and	and	CCONJ
dti-2277	462	30	late	late	ADJ
dti-2277	462	31	events	event	NOUN
dti-2277	462	32	in	in	ADP
dti-2277	462	33	hiv-1	hiv-1	ADJ
dti-2277	462	34	replication	replication	NOUN
dti-2277	462	35	.	.	PUNCT
dti-2277	463	1	j.	j.	PROPN
dti-2277	463	2	virol	virol	PROPN
dti-2277	463	3	.	.	PUNCT
dti-2277	463	4	,	,	PUNCT
dti-2277	464	1	69:814–824	69:814–824	PROPN
dti-2277	464	2	.	.	PUNCT
dti-2277	465	1	stremlau	stremlau	NOUN
dti-2277	465	2	,	,	PUNCT
dti-2277	465	3	m.	m.	NOUN
dti-2277	465	4	,	,	PUNCT
dti-2277	465	5	owens	owens	PROPN
dti-2277	465	6	,	,	PUNCT
dti-2277	465	7	c.m	c.m	PROPN
dti-2277	465	8	.	.	PROPN
dti-2277	465	9	,	,	PUNCT
dti-2277	465	10	perron	perron	PROPN
dti-2277	465	11	,	,	PUNCT
dti-2277	465	12	m.j	m.j	PROPN
dti-2277	465	13	.	.	PROPN
dti-2277	465	14	,	,	PUNCT
dti-2277	465	15	kiessling	kiessling	NOUN
dti-2277	465	16	,	,	PUNCT
dti-2277	465	17	m.	m.	NOUN
dti-2277	465	18	,	,	PUNCT
dti-2277	465	19	autissier	autissier	ADV
dti-2277	465	20	,	,	PUNCT
dti-2277	465	21	p.	p.	NOUN
dti-2277	465	22	and	and	CCONJ
dti-2277	465	23	sodroski	sodroski	PROPN
dti-2277	465	24	,	,	PUNCT
dti-2277	465	25	j.	j.	PROPN
dti-2277	465	26	2004	2004	NUM
dti-2277	465	27	.	.	PUNCT
dti-2277	466	1	the	the	DET
dti-2277	466	2	cytoplasmic	cytoplasmic	ADJ
dti-2277	466	3	body	body	NOUN
dti-2277	466	4	component	component	NOUN
dti-2277	466	5	trim5alpha	trim5alpha	PROPN
dti-2277	466	6	restricts	restrict	VERB
dti-2277	466	7	hiv-1	hiv-1	ADJ
dti-2277	466	8	infection	infection	NOUN
dti-2277	466	9	in	in	ADP
dti-2277	466	10	old	old	ADJ
dti-2277	466	11	world	world	NOUN
dti-2277	466	12	monkeys	monkey	NOUN
dti-2277	466	13	.	.	PUNCT
dti-2277	467	1	nature	nature	NOUN
dti-2277	467	2	,	,	PUNCT
dti-2277	467	3	427:848–853	427:848–853	NOUN
dti-2277	467	4	.	.	PUNCT
dti-2277	468	1	syed	syed	PROPN
dti-2277	468	2	,	,	PUNCT
dti-2277	468	3	f.	f.	PROPN
dti-2277	468	4	,	,	PUNCT
dti-2277	468	5	rycyzyn	rycyzyn	PROPN
dti-2277	468	6	,	,	PUNCT
dti-2277	468	7	m.a	m.a	PROPN
dti-2277	468	8	.	.	PROPN
dti-2277	468	9	,	,	PUNCT
dti-2277	468	10	westgate	westgate	PROPN
dti-2277	468	11	,	,	PUNCT
dti-2277	468	12	l.	l.	PROPN
dti-2277	468	13	and	and	CCONJ
dti-2277	468	14	clevenger	clevenger	PROPN
dti-2277	468	15	,	,	PUNCT
dti-2277	468	16	c.v	c.v	PROPN
dti-2277	468	17	.	.	PROPN
dti-2277	468	18	2003	2003	NUM
dti-2277	468	19	.	.	PUNCT
dti-2277	469	1	a	a	DET
dti-2277	469	2	novel	novel	ADJ
dti-2277	469	3	and	and	CCONJ
dti-2277	469	4	functional	functional	ADJ
dti-2277	469	5	interaction	interaction	NOUN
dti-2277	469	6	between	between	ADP
dti-2277	469	7	cyclophilin	cyclophilin	PROPN
dti-2277	469	8	a	a	PROPN
dti-2277	469	9	and	and	CCONJ
dti-2277	469	10	prolactin	prolactin	ADJ
dti-2277	469	11	receptor	receptor	NOUN
dti-2277	469	12	.	.	PUNCT
dti-2277	470	1	endocrine	endocrine	PROPN
dti-2277	470	2	,	,	PUNCT
dti-2277	470	3	20:83–90	20:83–90	PROPN
dti-2277	470	4	.	.	PUNCT
dti-2277	471	1	takahashi	takahashi	PROPN
dti-2277	471	2	,	,	PUNCT
dti-2277	471	3	n.	n.	PROPN
dti-2277	471	4	1999	1999	NUM
dti-2277	471	5	.	.	PUNCT
dti-2277	472	1	pharmacodynamics	pharmacodynamic	NOUN
dti-2277	472	2	of	of	ADP
dti-2277	472	3	ciclosporin	ciclosporin	NOUN
dti-2277	472	4	a	a	DET
dti-2277	472	5	(	(	PUNCT
dti-2277	472	6	cyclosporine	cyclosporine	NOUN
dti-2277	472	7	)	)	PUNCT
dti-2277	472	8	.	.	PUNCT
dti-2277	473	1	clin	clin	PROPN
dti-2277	473	2	.	.	PUNCT
dti-2277	474	1	exp	exp	PROPN
dti-2277	474	2	.	.	PUNCT
dti-2277	474	3	nephrol	nephrol	PROPN
dti-2277	474	4	.	.	PUNCT
dti-2277	474	5	,	,	PUNCT
dti-2277	474	6	3	3	NUM
dti-2277	474	7	:	:	PUNCT
dti-2277	474	8	s16	s16	NOUN
dti-2277	474	9	–	–	PUNCT
dti-2277	474	10	s26	s26	PROPN
dti-2277	474	11	.	.	PUNCT
dti-2277	475	1	takahashi	takahashi	PROPN
dti-2277	475	2	,	,	PUNCT
dti-2277	475	3	n.	n.	PROPN
dti-2277	475	4	,	,	PUNCT
dti-2277	475	5	hayano	hayano	NOUN
dti-2277	475	6	,	,	PUNCT
dti-2277	475	7	t.	t.	PROPN
dti-2277	475	8	and	and	CCONJ
dti-2277	475	9	suzuki	suzuki	PROPN
dti-2277	475	10	,	,	PUNCT
dti-2277	475	11	m.	m.	NOUN
dti-2277	475	12	1989	1989	NUM
dti-2277	475	13	.	.	PUNCT
dti-2277	476	1	peptidyl	peptidyl	NOUN
dti-2277	476	2	-	-	PUNCT
dti-2277	476	3	prolyl	prolyl	NOUN
dti-2277	476	4	cis	cis	NOUN
dti-2277	476	5	-	-	PUNCT
dti-2277	476	6	trans	trans	ADJ
dti-2277	476	7	isomerase	isomerase	NOUN
dti-2277	476	8	is	be	AUX
dti-2277	476	9	the	the	DET
dti-2277	476	10	cyclosporin	cyclosporin	NOUN
dti-2277	476	11	a	a	ADV
dti-2277	476	12	-	-	PUNCT
dti-2277	476	13	binding	bind	VERB
dti-2277	476	14	protein	protein	NOUN
dti-2277	476	15	cyclophilin	cyclophilin	PROPN
dti-2277	476	16	.	.	PUNCT
dti-2277	477	1	nature	nature	NOUN
dti-2277	477	2	,	,	PUNCT
dti-2277	477	3	337:473–475	337:473–475	NUM
dti-2277	477	4	.	.	PUNCT
dti-2277	478	1	tanveer	tanveer	PROPN
dti-2277	478	2	,	,	PUNCT
dti-2277	478	3	a.	a.	PROPN
dti-2277	478	4	,	,	PUNCT
dti-2277	478	5	virji	virji	PROPN
dti-2277	478	6	,	,	PUNCT
dti-2277	478	7	s.	s.	PROPN
dti-2277	478	8	,	,	PUNCT
dti-2277	478	9	andreeva	andreeva	PROPN
dti-2277	478	10	,	,	PUNCT
dti-2277	478	11	l.	l.	PROPN
dti-2277	478	12	,	,	PUNCT
dti-2277	478	13	totty	totty	PROPN
dti-2277	478	14	,	,	PUNCT
dti-2277	478	15	n.f	n.f	PROPN
dti-2277	478	16	.	.	PROPN
dti-2277	478	17	,	,	PUNCT
dti-2277	478	18	hsuan	hsuan	PROPN
dti-2277	478	19	,	,	PUNCT
dti-2277	478	20	j.j	j.j	PROPN
dti-2277	478	21	.	.	PROPN
dti-2277	478	22	,	,	PUNCT
dti-2277	478	23	ward	ward	NOUN
dti-2277	478	24	,	,	PUNCT
dti-2277	478	25	j.m	j.m	PROPN
dti-2277	478	26	.	.	PROPN
dti-2277	478	27	and	and	CCONJ
dti-2277	478	28	crompton	crompton	PROPN
dti-2277	478	29	,	,	PUNCT
dti-2277	478	30	m.	m.	NOUN
dti-2277	478	31	1996	1996	NUM
dti-2277	478	32	.	.	PUNCT
dti-2277	479	1	involvement	involvement	NOUN
dti-2277	479	2	of	of	ADP
dti-2277	479	3	cyclophilin	cyclophilin	PROPN
dti-2277	479	4	d	d	PROPN
dti-2277	479	5	in	in	ADP
dti-2277	479	6	the	the	DET
dti-2277	479	7	activation	activation	NOUN
dti-2277	479	8	of	of	ADP
dti-2277	479	9	a	a	DET
dti-2277	479	10	mitochondrial	mitochondrial	ADJ
dti-2277	479	11	pore	pore	NOUN
dti-2277	479	12	by	by	ADP
dti-2277	479	13	ca2	ca2	PROPN
dti-2277	479	14	+	+	PROPN
dti-2277	479	15	and	and	CCONJ
dti-2277	479	16	oxidant	oxidant	ADJ
dti-2277	479	17	stress	stress	NOUN
dti-2277	479	18	.	.	PUNCT
dti-2277	480	1	eur	eur	PROPN
dti-2277	480	2	.	.	PUNCT
dti-2277	481	1	j.	j.	PROPN
dti-2277	481	2	biochem	biochem	PROPN
dti-2277	481	3	.	.	PUNCT
dti-2277	481	4	,	,	PUNCT
dti-2277	481	5	238:166–172	238:166–172	NOUN
dti-2277	481	6	.	.	PUNCT
dti-2277	482	1	thali	thali	PROPN
dti-2277	482	2	,	,	PUNCT
dti-2277	482	3	m.	m.	NOUN
dti-2277	482	4	,	,	PUNCT
dti-2277	482	5	bukovsky	bukovsky	NOUN
dti-2277	482	6	,	,	PUNCT
dti-2277	482	7	a.	a.	NOUN
dti-2277	482	8	,	,	PUNCT
dti-2277	482	9	kondo	kondo	PROPN
dti-2277	482	10	,	,	PUNCT
dti-2277	482	11	e.	e.	PROPN
dti-2277	482	12	,	,	PUNCT
dti-2277	482	13	rosenwirth	rosenwirth	PROPN
dti-2277	482	14	,	,	PUNCT
dti-2277	482	15	b.	b.	PROPN
dti-2277	482	16	,	,	PUNCT
dti-2277	482	17	walsh	walsh	PROPN
dti-2277	482	18	,	,	PUNCT
dti-2277	482	19	c.t	c.t	PROPN
dti-2277	482	20	.	.	PROPN
dti-2277	482	21	,	,	PUNCT
dti-2277	482	22	sodroski	sodroski	PROPN
dti-2277	482	23	,	,	PUNCT
dti-2277	482	24	j.	j.	PROPN
dti-2277	482	25	and	and	CCONJ
dti-2277	482	26	gottlinger	gottlinger	PROPN
dti-2277	482	27	,	,	PUNCT
dti-2277	482	28	h.g	h.g	PROPN
dti-2277	482	29	.	.	PROPN
dti-2277	482	30	1994	1994	NUM
dti-2277	482	31	.	.	PUNCT
dti-2277	483	1	functional	functional	ADJ
dti-2277	483	2	association	association	NOUN
dti-2277	483	3	of	of	ADP
dti-2277	483	4	cyclophilin	cyclophilin	PROPN
dti-2277	483	5	a	a	DET
dti-2277	483	6	with	with	ADP
dti-2277	483	7	hiv-1	hiv-1	ADJ
dti-2277	483	8	virions	virion	NOUN
dti-2277	483	9	.	.	PUNCT
dti-2277	484	1	nature	nature	NOUN
dti-2277	484	2	,	,	PUNCT
dti-2277	484	3	372:363–365	372:363–365	NUM
dti-2277	484	4	.	.	PUNCT
dti-2277	485	1	towers	tower	NOUN
dti-2277	485	2	,	,	PUNCT
dti-2277	485	3	g.j	g.j	PROPN
dti-2277	485	4	.	.	PROPN
dti-2277	485	5	,	,	PUNCT
dti-2277	485	6	hatziioannou	hatziioannou	NOUN
dti-2277	485	7	,	,	PUNCT
dti-2277	485	8	t.	t.	PROPN
dti-2277	485	9	,	,	PUNCT
dti-2277	485	10	cowan	cowan	PROPN
dti-2277	485	11	,	,	PUNCT
dti-2277	485	12	s.	s.	PROPN
dti-2277	485	13	,	,	PUNCT
dti-2277	485	14	goff	goff	PROPN
dti-2277	485	15	,	,	PUNCT
dti-2277	485	16	s.p	s.p	PROPN
dti-2277	485	17	.	.	PROPN
dti-2277	485	18	,	,	PUNCT
dti-2277	485	19	luban	luban	PROPN
dti-2277	485	20	,	,	PUNCT
dti-2277	485	21	j.	j.	PROPN
dti-2277	485	22	and	and	CCONJ
dti-2277	485	23	bieniasz	bieniasz	PROPN
dti-2277	485	24	,	,	PUNCT
dti-2277	485	25	p.d	p.d	PROPN
dti-2277	485	26	.	.	PROPN
dti-2277	485	27	2003	2003	NUM
dti-2277	485	28	.	.	PUNCT
dti-2277	486	1	cyclophilin	cyclophilin	PROPN
dti-2277	486	2	a	a	DET
dti-2277	486	3	modulates	modulate	NOUN
dti-2277	486	4	the	the	DET
dti-2277	486	5	sensitivity	sensitivity	NOUN
dti-2277	486	6	of	of	ADP
dti-2277	486	7	hiv-1	hiv-1	X
dti-2277	486	8	to	to	PART
dti-2277	486	9	host	host	NOUN
dti-2277	486	10	restriction	restriction	NOUN
dti-2277	486	11	factors	factor	NOUN
dti-2277	486	12	.	.	PUNCT
dti-2277	487	1	nat	nat	PROPN
dti-2277	487	2	.	.	PUNCT
dti-2277	488	1	med	med	PROPN
dti-2277	488	2	.	.	PROPN
dti-2277	488	3	,	,	PUNCT
dti-2277	489	1	9:1138–1143	9:1138–1143	NUM
dti-2277	489	2	.	.	PUNCT
dti-2277	490	1	tran	tran	PROPN
dti-2277	490	2	,	,	PUNCT
dti-2277	490	3	d.d	d.d	PROPN
dti-2277	490	4	.	.	PROPN
dti-2277	490	5	,	,	PUNCT
dti-2277	490	6	edgar	edgar	PROPN
dti-2277	490	7	,	,	PUNCT
dti-2277	490	8	c.e	c.e	PROPN
dti-2277	490	9	.	.	PROPN
dti-2277	490	10	,	,	PUNCT
dti-2277	490	11	heckman	heckman	PROPN
dti-2277	490	12	,	,	PUNCT
dti-2277	490	13	k.l	k.l	PROPN
dti-2277	490	14	.	.	PROPN
dti-2277	490	15	,	,	PUNCT
dti-2277	490	16	sutor	sutor	PROPN
dti-2277	490	17	,	,	PUNCT
dti-2277	490	18	s.l	s.l	PROPN
dti-2277	490	19	.	.	PROPN
dti-2277	490	20	,	,	PUNCT
dti-2277	490	21	huntoon	huntoon	PROPN
dti-2277	490	22	,	,	PUNCT
dti-2277	490	23	c.j	c.j	PROPN
dti-2277	490	24	.	.	PROPN
dti-2277	490	25	,	,	PUNCT
dti-2277	490	26	van	van	PROPN
dti-2277	490	27	deursen	deursen	NOUN
dti-2277	490	28	,	,	PUNCT
dti-2277	490	29	j.	j.	PROPN
dti-2277	490	30	,	,	PUNCT
dti-2277	490	31	mckean	mckean	PROPN
dti-2277	490	32	,	,	PUNCT
dti-2277	490	33	d.l	d.l	PROPN
dti-2277	490	34	.	.	PROPN
dti-2277	490	35	and	and	CCONJ
dti-2277	490	36	bram	bram	PROPN
dti-2277	490	37	,	,	PUNCT
dti-2277	490	38	r.j	r.j	PROPN
dti-2277	490	39	.	.	PROPN
dti-2277	490	40	2005	2005	NUM
dti-2277	490	41	.	.	PUNCT
dti-2277	491	1	caml	caml	PROPN
dti-2277	491	2	is	be	AUX
dti-2277	491	3	a	a	DET
dti-2277	491	4	p56lck	p56lck	NOUN
dti-2277	491	5	-	-	PUNCT
dti-2277	491	6	interacting	interact	VERB
dti-2277	491	7	protein	protein	NOUN
dti-2277	491	8	that	that	PRON
dti-2277	491	9	is	be	AUX
dti-2277	491	10	required	require	VERB
dti-2277	491	11	for	for	ADP
dti-2277	491	12	thymocyte	thymocyte	NOUN
dti-2277	491	13	development	development	NOUN
dti-2277	491	14	.	.	PUNCT
dti-2277	492	1	immunity	immunity	NOUN
dti-2277	492	2	,	,	PUNCT
dti-2277	492	3	23:139–152	23:139–152	NUM
dti-2277	492	4	.	.	PUNCT
dti-2277	492	5	tu	tu	PROPN
dti-2277	492	6	,	,	PUNCT
dti-2277	492	7	h.	h.	PROPN
dti-2277	492	8	,	,	PUNCT
dti-2277	492	9	gao	gao	PROPN
dti-2277	492	10	,	,	PUNCT
dti-2277	492	11	l.	l.	PROPN
dti-2277	492	12	,	,	PUNCT
dti-2277	492	13	shi	shi	PROPN
dti-2277	492	14	,	,	PUNCT
dti-2277	492	15	s.t	s.t	PROPN
dti-2277	492	16	.	.	PROPN
dti-2277	492	17	,	,	PUNCT
dti-2277	492	18	taylor	taylor	PROPN
dti-2277	492	19	,	,	PUNCT
dti-2277	492	20	d.r	d.r	PROPN
dti-2277	492	21	.	.	PROPN
dti-2277	492	22	,	,	PUNCT
dti-2277	492	23	yang	yang	PROPN
dti-2277	492	24	,	,	PUNCT
dti-2277	492	25	t.	t.	PROPN
dti-2277	492	26	,	,	PUNCT
dti-2277	492	27	mircheff	mircheff	PROPN
dti-2277	492	28	,	,	PUNCT
dti-2277	492	29	a.k	a.k	PROPN
dti-2277	492	30	.	.	PROPN
dti-2277	492	31	,	,	PUNCT
dti-2277	492	32	wen	wen	PROPN
dti-2277	492	33	,	,	PUNCT
dti-2277	492	34	y.	y.	PROPN
dti-2277	492	35	,	,	PUNCT
dti-2277	492	36	gorbalenya	gorbalenya	NOUN
dti-2277	492	37	,	,	PUNCT
dti-2277	492	38	a.e	a.e	PROPN
dti-2277	492	39	.	.	PROPN
dti-2277	492	40	,	,	PUNCT
dti-2277	492	41	hwang	hwang	PROPN
dti-2277	492	42	,	,	PUNCT
dti-2277	492	43	s.b	s.b	PROPN
dti-2277	492	44	.	.	PROPN
dti-2277	492	45	and	and	CCONJ
dti-2277	492	46	lai	lai	PROPN
dti-2277	492	47	,	,	PUNCT
dti-2277	492	48	m.m	m.m	PROPN
dti-2277	492	49	.	.	PROPN
dti-2277	492	50	1999	1999	NUM
dti-2277	492	51	.	.	PUNCT
dti-2277	493	1	hepatitis	hepatitis	PROPN
dti-2277	493	2	c	c	PROPN
dti-2277	493	3	virus	virus	PROPN
dti-2277	493	4	rna	rna	NOUN
dti-2277	493	5	polymerase	polymerase	NOUN
dti-2277	493	6	and	and	CCONJ
dti-2277	493	7	ns5a	ns5a	PROPN
dti-2277	493	8	complex	complex	NOUN
dti-2277	493	9	with	with	ADP
dti-2277	493	10	a	a	DET
dti-2277	493	11	snare	snare	NOUN
dti-2277	493	12	-	-	PUNCT
dti-2277	493	13	like	like	ADJ
dti-2277	493	14	protein	protein	NOUN
dti-2277	493	15	.	.	PUNCT
dti-2277	494	1	virology	virology	NOUN
dti-2277	494	2	,	,	PUNCT
dti-2277	494	3	263:30–41	263:30–41	NUM
dti-2277	494	4	.	.	PUNCT
dti-2277	495	1	waldmeier	waldmei	ADJ
dti-2277	495	2	,	,	PUNCT
dti-2277	495	3	p.c	p.c	PROPN
dti-2277	495	4	.	.	PROPN
dti-2277	495	5	,	,	PUNCT
dti-2277	495	6	zimmermann	zimmermann	PROPN
dti-2277	495	7	,	,	PUNCT
dti-2277	495	8	k.	k.	PROPN
dti-2277	495	9	,	,	PUNCT
dti-2277	495	10	qian	qian	PROPN
dti-2277	495	11	,	,	PUNCT
dti-2277	495	12	t.	t.	PROPN
dti-2277	495	13	,	,	PUNCT
dti-2277	495	14	tintelnot	tintelnot	NOUN
dti-2277	495	15	-	-	PUNCT
dti-2277	495	16	blomley	blomley	ADJ
dti-2277	495	17	,	,	PUNCT
dti-2277	495	18	m.	m.	NOUN
dti-2277	495	19	and	and	CCONJ
dti-2277	495	20	lemasters	lemaster	NOUN
dti-2277	495	21	,	,	PUNCT
dti-2277	495	22	j.j	j.j	PROPN
dti-2277	495	23	.	.	PROPN
dti-2277	495	24	2003	2003	NUM
dti-2277	495	25	.	.	PUNCT
dti-2277	496	1	cyclophilin	cyclophilin	PROPN
dti-2277	496	2	d	d	PROPN
dti-2277	496	3	as	as	ADP
dti-2277	496	4	a	a	DET
dti-2277	496	5	drug	drug	NOUN
dti-2277	496	6	target	target	NOUN
dti-2277	496	7	.	.	PUNCT
dti-2277	497	1	curr	curr	AUX
dti-2277	497	2	.	.	PUNCT
dti-2277	497	3	med	med	PROPN
dti-2277	497	4	.	.	PROPN
dti-2277	497	5	chem	chem	PROPN
dti-2277	497	6	.	.	PUNCT
dti-2277	497	7	,	,	PUNCT
dti-2277	497	8	10:1485–1506	10:1485–1506	NUM
dti-2277	497	9	.	.	PUNCT
dti-2277	498	1	wang	wang	PROPN
dti-2277	498	2	,	,	PUNCT
dti-2277	498	3	b.b	b.b	PROPN
dti-2277	498	4	.	.	PROPN
dti-2277	498	5	,	,	PUNCT
dti-2277	498	6	hayenga	hayenga	PROPN
dti-2277	498	7	,	,	PUNCT
dti-2277	498	8	k.j	k.j	PROPN
dti-2277	498	9	.	.	PROPN
dti-2277	498	10	,	,	PUNCT
dti-2277	498	11	payan	payan	PROPN
dti-2277	498	12	,	,	PUNCT
dti-2277	498	13	d.g	d.g	PROPN
dti-2277	498	14	.	.	PROPN
dti-2277	498	15	and	and	CCONJ
dti-2277	498	16	fisher	fisher	PROPN
dti-2277	498	17	,	,	PUNCT
dti-2277	498	18	j.m	j.m	PROPN
dti-2277	498	19	.	.	NOUN
dti-2277	498	20	1996	1996	NUM
dti-2277	498	21	.	.	PUNCT
dti-2277	499	1	identifi	identifi	PROPN
dti-2277	499	2	cation	cation	NOUN
dti-2277	499	3	of	of	ADP
dti-2277	499	4	a	a	DET
dti-2277	499	5	nuclear	nuclear	NOUN
dti-2277	499	6	-	-	PUNCT
dti-2277	499	7	specifi	specifi	PROPN
dti-2277	499	8	c	c	PROPN
dti-2277	499	9	cyclophilin	cyclophilin	PROPN
dti-2277	499	10	which	which	PRON
dti-2277	499	11	interacts	interact	VERB
dti-2277	499	12	with	with	ADP
dti-2277	499	13	the	the	DET
dti-2277	499	14	proteinase	proteinase	NOUN
dti-2277	499	15	inhibitor	inhibitor	PROPN
dti-2277	499	16	eglin	eglin	PROPN
dti-2277	499	17	c.	c.	PROPN
dti-2277	499	18	biochem	biochem	PROPN
dti-2277	499	19	.	.	PUNCT
dti-2277	500	1	j.	j.	PROPN
dti-2277	500	2	,	,	PUNCT
dti-2277	500	3	314(pt	314(pt	PROPN
dti-2277	500	4	1):313–319	1):313–319	NUM
dti-2277	500	5	.	.	PUNCT
dti-2277	501	1	wang	wang	PROPN
dti-2277	501	2	,	,	PUNCT
dti-2277	501	3	c.	c.	PROPN
dti-2277	501	4	,	,	PUNCT
dti-2277	501	5	gale	gale	NOUN
dti-2277	501	6	,	,	PUNCT
dti-2277	501	7	m.	m.	NOUN
dti-2277	501	8	,	,	PUNCT
dti-2277	501	9	jr	jr	PROPN
dti-2277	501	10	.	.	PROPN
dti-2277	501	11	,	,	PUNCT
dti-2277	501	12	keller	keller	PROPN
dti-2277	501	13	,	,	PUNCT
dti-2277	501	14	b.	b.	PROPN
dti-2277	501	15	c.	c.	PROPN
dti-2277	501	16	,	,	PUNCT
dti-2277	501	17	huang	huang	PROPN
dti-2277	501	18	,	,	PUNCT
dti-2277	501	19	h.	h.	PROPN
dti-2277	501	20	,	,	PUNCT
dti-2277	501	21	brown	brown	PROPN
dti-2277	501	22	,	,	PUNCT
dti-2277	501	23	m.s	m.s	PROPN
dti-2277	501	24	.	.	PROPN
dti-2277	501	25	,	,	PUNCT
dti-2277	501	26	goldstein	goldstein	PROPN
dti-2277	501	27	,	,	PUNCT
dti-2277	501	28	j.l	j.l	PROPN
dti-2277	501	29	.	.	PROPN
dti-2277	501	30	and	and	CCONJ
dti-2277	501	31	ye	ye	PROPN
dti-2277	501	32	,	,	PUNCT
dti-2277	501	33	j.	j.	PROPN
dti-2277	501	34	2005	2005	NUM
dti-2277	501	35	.	.	PUNCT
dti-2277	502	1	identifi	identifi	PROPN
dti-2277	502	2	cation	cation	NOUN
dti-2277	502	3	of	of	ADP
dti-2277	502	4	fbl2	fbl2	PROPN
dti-2277	502	5	as	as	ADP
dti-2277	502	6	a	a	DET
dti-2277	502	7	geranylgeranylated	geranylgeranylated	ADJ
dti-2277	502	8	cellular	cellular	ADJ
dti-2277	502	9	protein	protein	NOUN
dti-2277	502	10	required	require	VERB
dti-2277	502	11	for	for	ADP
dti-2277	502	12	hepatitis	hepatitis	PROPN
dti-2277	502	13	c	c	PROPN
dti-2277	502	14	virus	virus	NOUN
dti-2277	502	15	rna	rna	NOUN
dti-2277	502	16	replication	replication	NOUN
dti-2277	502	17	.	.	PUNCT
dti-2277	503	1	mol	mol	PROPN
dti-2277	503	2	.	.	PROPN
dti-2277	503	3	cell	cell	NOUN
dti-2277	503	4	.	.	PUNCT
dti-2277	503	5	,	,	PUNCT
dti-2277	504	1	18:425–434	18:425–434	NUM
dti-2277	504	2	.	.	PUNCT
dti-2277	505	1	watashi	watashi	PROPN
dti-2277	505	2	,	,	PUNCT
dti-2277	505	3	k.	k.	PROPN
dti-2277	505	4	,	,	PUNCT
dti-2277	505	5	hijikata	hijikata	PROPN
dti-2277	505	6	,	,	PUNCT
dti-2277	505	7	m.	m.	NOUN
dti-2277	505	8	,	,	PUNCT
dti-2277	505	9	hosaka	hosaka	NOUN
dti-2277	505	10	,	,	PUNCT
dti-2277	505	11	m.	m.	NOUN
dti-2277	505	12	,	,	PUNCT
dti-2277	505	13	yamaji	yamaji	NOUN
dti-2277	505	14	,	,	PUNCT
dti-2277	505	15	m.	m.	NOUN
dti-2277	505	16	and	and	CCONJ
dti-2277	505	17	shimotohno	shimotohno	NOUN
dti-2277	505	18	,	,	PUNCT
dti-2277	505	19	k.	k.	PROPN
dti-2277	505	20	2003	2003	NUM
dti-2277	505	21	.	.	PUNCT
dti-2277	506	1	cyclosporin	cyclosporin	NOUN
dti-2277	506	2	a	a	PRON
dti-2277	506	3	suppresses	suppress	VERB
dti-2277	506	4	replication	replication	NOUN
dti-2277	506	5	of	of	ADP
dti-2277	506	6	hepatitis	hepatitis	PROPN
dti-2277	506	7	c	c	PROPN
dti-2277	506	8	virus	virus	NOUN
dti-2277	506	9	genome	genome	NOUN
dti-2277	506	10	in	in	ADP
dti-2277	506	11	cultured	cultured	ADJ
dti-2277	506	12	hepatocytes	hepatocyte	NOUN
dti-2277	506	13	.	.	PUNCT
dti-2277	507	1	hepatology	hepatology	NOUN
dti-2277	507	2	,	,	PUNCT
dti-2277	507	3	38:1282–1288	38:1282–1288	PROPN
dti-2277	507	4	.	.	PUNCT
dti-2277	507	5	watashi	watashi	PROPN
dti-2277	507	6	,	,	PUNCT
dti-2277	507	7	k.	k.	PROPN
dti-2277	507	8	,	,	PUNCT
dti-2277	507	9	ishii	ishii	PROPN
dti-2277	507	10	,	,	PUNCT
dti-2277	507	11	n.	n.	NOUN
dti-2277	507	12	,	,	PUNCT
dti-2277	507	13	hijikata	hijikata	PROPN
dti-2277	507	14	,	,	PUNCT
dti-2277	507	15	m.	m.	NOUN
dti-2277	507	16	,	,	PUNCT
dti-2277	507	17	inoue	inoue	PROPN
dti-2277	507	18	,	,	PUNCT
dti-2277	507	19	d.	d.	PROPN
dti-2277	507	20	,	,	PUNCT
dti-2277	507	21	murata	murata	PROPN
dti-2277	507	22	,	,	PUNCT
dti-2277	507	23	t.	t.	PROPN
dti-2277	507	24	,	,	PUNCT
dti-2277	507	25	miyanari	miyanari	NOUN
dti-2277	507	26	,	,	PUNCT
dti-2277	507	27	y.	y.	NOUN
dti-2277	507	28	and	and	CCONJ
dti-2277	507	29	shimotohno	shimotohno	NOUN
dti-2277	507	30	,	,	PUNCT
dti-2277	507	31	k.	k.	PROPN
dti-2277	507	32	2005	2005	NUM
dti-2277	507	33	.	.	PUNCT
dti-2277	508	1	cyclophilin	cyclophilin	PROPN
dti-2277	508	2	b	b	PROPN
dti-2277	508	3	is	be	AUX
dti-2277	508	4	a	a	DET
dti-2277	508	5	functional	functional	ADJ
dti-2277	508	6	regulator	regulator	NOUN
dti-2277	508	7	of	of	ADP
dti-2277	508	8	hepatitis	hepatitis	PROPN
dti-2277	508	9	c	c	PROPN
dti-2277	508	10	virus	virus	PROPN
dti-2277	508	11	rna	rna	NOUN
dti-2277	508	12	polymerase	polymerase	NOUN
dti-2277	508	13	.	.	PUNCT
dti-2277	509	1	mol	mol	PROPN
dti-2277	509	2	.	.	PROPN
dti-2277	509	3	cell	cell	NOUN
dti-2277	509	4	.	.	PUNCT
dti-2277	510	1	,	,	PUNCT
dti-2277	510	2	19:111–122	19:111–122	NUM
dti-2277	510	3	.	.	PUNCT
dti-2277	510	4	drug	drug	NOUN
dti-2277	510	5	target	target	NOUN
dti-2277	510	6	insights	insight	NOUN
dti-2277	510	7	2007	2007	NUM
dti-2277	510	8	:	:	PUNCT
dti-2277	510	9	2	2	NUM
dti-2277	510	10	18	18	NUM
dti-2277	510	11	watashi	watashi	NOUN
dti-2277	510	12	and	and	CCONJ
dti-2277	510	13	shimotohno	shimotohno	NOUN
dti-2277	510	14	woodfi	woodfi	PROPN
dti-2277	510	15	eld	eld	PROPN
dti-2277	510	16	,	,	PUNCT
dti-2277	510	17	k.	k.	PROPN
dti-2277	510	18	,	,	PUNCT
dti-2277	510	19	ruck	ruck	NOUN
dti-2277	510	20	,	,	PUNCT
dti-2277	510	21	a.	a.	NOUN
dti-2277	510	22	,	,	PUNCT
dti-2277	510	23	brdiczka	brdiczka	PROPN
dti-2277	510	24	,	,	PUNCT
dti-2277	510	25	d.	d.	PROPN
dti-2277	510	26	and	and	CCONJ
dti-2277	510	27	halestrap	halestrap	PROPN
dti-2277	510	28	,	,	PUNCT
dti-2277	510	29	a.p	a.p	PROPN
dti-2277	510	30	.	.	PROPN
dti-2277	510	31	1998	1998	NUM
dti-2277	510	32	.	.	PUNCT
dti-2277	511	1	direct	direct	ADJ
dti-2277	511	2	demonstration	demonstration	NOUN
dti-2277	511	3	of	of	ADP
dti-2277	511	4	a	a	DET
dti-2277	511	5	specifi	specifi	PROPN
dti-2277	511	6	c	c	NOUN
dti-2277	511	7	interaction	interaction	NOUN
dti-2277	511	8	between	between	ADP
dti-2277	511	9	cyclophilin	cyclophilin	PROPN
dti-2277	511	10	-	-	PUNCT
dti-2277	511	11	d	d	PROPN
dti-2277	511	12	and	and	CCONJ
dti-2277	511	13	the	the	DET
dti-2277	511	14	adenine	adenine	ADJ
dti-2277	511	15	nucleotide	nucleotide	NOUN
dti-2277	511	16	translocase	translocase	NOUN
dti-2277	511	17	confi	confi	VERB
dti-2277	511	18	rms	rm	VERB
dti-2277	511	19	their	their	PRON
dti-2277	511	20	role	role	NOUN
dti-2277	511	21	in	in	ADP
dti-2277	511	22	the	the	DET
dti-2277	511	23	mitochondrial	mitochondrial	ADJ
dti-2277	511	24	permeability	permeability	NOUN
dti-2277	511	25	transition	transition	NOUN
dti-2277	511	26	.	.	PUNCT
dti-2277	512	1	biochem	biochem	PROPN
dti-2277	512	2	.	.	PUNCT
dti-2277	513	1	j.	j.	PROPN
dti-2277	513	2	,	,	PUNCT
dti-2277	513	3	336(pt	336(pt	NUM
dti-2277	513	4	2):287–290	2):287–290	NUM
dti-2277	513	5	.	.	PUNCT
dti-2277	514	1	xu	xu	PROPN
dti-2277	514	2	,	,	PUNCT
dti-2277	514	3	q.	q.	PROPN
dti-2277	514	4	,	,	PUNCT
dti-2277	514	5	leiva	leiva	PROPN
dti-2277	514	6	,	,	PUNCT
dti-2277	514	7	m.c	m.c	PROPN
dti-2277	514	8	.	.	PROPN
dti-2277	514	9	,	,	PUNCT
dti-2277	514	10	fischkoff	fischkoff	PROPN
dti-2277	514	11	,	,	PUNCT
dti-2277	514	12	s.a	s.a	PROPN
dti-2277	514	13	.	.	PROPN
dti-2277	514	14	,	,	PUNCT
dti-2277	514	15	handschumacher	handschumacher	PROPN
dti-2277	514	16	,	,	PUNCT
dti-2277	514	17	r.e	r.e	PROPN
dti-2277	514	18	.	.	PROPN
dti-2277	514	19	and	and	CCONJ
dti-2277	514	20	lyttle	lyttle	PROPN
dti-2277	514	21	,	,	PUNCT
dti-2277	514	22	c.	c.	PROPN
dti-2277	514	23	r.	r.	PROPN
dti-2277	514	24	1992	1992	NUM
dti-2277	514	25	.	.	PUNCT
dti-2277	515	1	leukocyte	leukocyte	ADJ
dti-2277	515	2	chemotactic	chemotactic	ADJ
dti-2277	515	3	activity	activity	NOUN
dti-2277	515	4	of	of	ADP
dti-2277	515	5	cyclophilin	cyclophilin	PROPN
dti-2277	515	6	.	.	PUNCT
dti-2277	516	1	j.	j.	PROPN
dti-2277	516	2	biol	biol	PROPN
dti-2277	516	3	.	.	PUNCT
dti-2277	517	1	chem	chem	PROPN
dti-2277	517	2	.	.	PUNCT
dti-2277	517	3	,	,	PUNCT
dti-2277	518	1	267:11968–11971	267:11968–11971	X
dti-2277	518	2	.	.	PUNCT
dti-2277	519	1	yang	yang	PROPN
dti-2277	519	2	,	,	PUNCT
dti-2277	519	3	w.m	w.m	PROPN
dti-2277	519	4	.	.	PROPN
dti-2277	519	5	,	,	PUNCT
dti-2277	519	6	inouye	inouye	PROPN
dti-2277	519	7	,	,	PUNCT
dti-2277	519	8	c.j	c.j	PROPN
dti-2277	519	9	.	.	PROPN
dti-2277	519	10	and	and	CCONJ
dti-2277	519	11	seto	seto	VERB
dti-2277	519	12	,	,	PUNCT
dti-2277	519	13	e.	e.	PROPN
dti-2277	519	14	1995	1995	NUM
dti-2277	519	15	.	.	PUNCT
dti-2277	520	1	cyclophilin	cyclophilin	PROPN
dti-2277	520	2	a	a	PRON
dti-2277	520	3	and	and	CCONJ
dti-2277	520	4	fkbp12	fkbp12	NOUN
dti-2277	520	5	interact	interact	VERB
dti-2277	520	6	with	with	ADP
dti-2277	520	7	yy1	yy1	NOUN
dti-2277	520	8	and	and	CCONJ
dti-2277	520	9	alter	alter	VERB
dti-2277	520	10	its	its	PRON
dti-2277	520	11	transcriptional	transcriptional	ADJ
dti-2277	520	12	activity	activity	NOUN
dti-2277	520	13	.	.	PUNCT
dti-2277	521	1	j.	j.	PROPN
dti-2277	521	2	biol	biol	PROPN
dti-2277	521	3	.	.	PUNCT
dti-2277	522	1	chem	chem	PROPN
dti-2277	522	2	.	.	PUNCT
dti-2277	523	1	,	,	PUNCT
dti-2277	523	2	270:15187–15193	270:15187–15193	PROPN
dti-2277	523	3	.	.	PUNCT
dti-2277	524	1	yokoyama	yokoyama	PROPN
dti-2277	524	2	,	,	PUNCT
dti-2277	524	3	n.	n.	PROPN
dti-2277	524	4	,	,	PUNCT
dti-2277	524	5	hayashi	hayashi	PROPN
dti-2277	524	6	,	,	PUNCT
dti-2277	524	7	n.	n.	PROPN
dti-2277	524	8	,	,	PUNCT
dti-2277	524	9	seki	seki	PROPN
dti-2277	524	10	,	,	PUNCT
dti-2277	524	11	t.	t.	PROPN
dti-2277	524	12	,	,	PUNCT
dti-2277	524	13	pante	pante	PROPN
dti-2277	524	14	,	,	PUNCT
dti-2277	524	15	n.	n.	NOUN
dti-2277	524	16	,	,	PUNCT
dti-2277	524	17	ohba	ohba	NOUN
dti-2277	524	18	,	,	PUNCT
dti-2277	524	19	t.	t.	PROPN
dti-2277	524	20	,	,	PUNCT
dti-2277	524	21	nishii	nishii	NOUN
dti-2277	524	22	,	,	PUNCT
dti-2277	524	23	k.	k.	PROPN
dti-2277	524	24	,	,	PUNCT
dti-2277	524	25	kuma	kuma	PROPN
dti-2277	524	26	,	,	PUNCT
dti-2277	524	27	k.	k.	PROPN
dti-2277	524	28	,	,	PUNCT
dti-2277	524	29	hayashida	hayashida	PROPN
dti-2277	524	30	,	,	PUNCT
dti-2277	524	31	t.	t.	PROPN
dti-2277	524	32	,	,	PUNCT
dti-2277	524	33	miyata	miyata	PROPN
dti-2277	524	34	,	,	PUNCT
dti-2277	524	35	t.	t.	PROPN
dti-2277	524	36	,	,	PUNCT
dti-2277	524	37	aebi	aebi	ADJ
dti-2277	524	38	,	,	PUNCT
dti-2277	524	39	u.	u.	PROPN
dti-2277	524	40	and	and	CCONJ
dti-2277	524	41	et	et	PROPN
dti-2277	524	42	al	al	PROPN
dti-2277	524	43	.	.	PROPN
dti-2277	524	44	1995	1995	NUM
dti-2277	524	45	.	.	PUNCT
dti-2277	525	1	a	a	DET
dti-2277	525	2	giant	giant	ADJ
dti-2277	525	3	nucleopore	nucleopore	NOUN
dti-2277	525	4	protein	protein	NOUN
dti-2277	525	5	that	that	PRON
dti-2277	525	6	binds	bind	VERB
dti-2277	525	7	ran	ran	NOUN
dti-2277	525	8	/	/	SYM
dti-2277	525	9	tc4	tc4	PROPN
dti-2277	525	10	.	.	PUNCT
dti-2277	526	1	nature	nature	PROPN
dti-2277	526	2	,	,	PUNCT
dti-2277	526	3	376:184–188	376:184–188	NUM
dti-2277	526	4	.	.	PUNCT
dti-2277	527	1	yurchenko	yurchenko	PROPN
dti-2277	527	2	,	,	PUNCT
dti-2277	527	3	v.	v.	ADV
dti-2277	527	4	,	,	PUNCT
dti-2277	527	5	o’connor	o’connor	ADV
dti-2277	527	6	,	,	PUNCT
dti-2277	527	7	m.	m.	NOUN
dti-2277	527	8	,	,	PUNCT
dti-2277	527	9	dai	dai	PROPN
dti-2277	527	10	,	,	PUNCT
dti-2277	527	11	w.	w.	PROPN
dti-2277	527	12	w.	w.	PROPN
dti-2277	527	13	,	,	PUNCT
dti-2277	527	14	guo	guo	PROPN
dti-2277	527	15	,	,	PUNCT
dti-2277	527	16	h.	h.	PROPN
dti-2277	527	17	,	,	PUNCT
dti-2277	527	18	toole	toole	PROPN
dti-2277	527	19	,	,	PUNCT
dti-2277	527	20	b.	b.	PROPN
dti-2277	527	21	,	,	PUNCT
dti-2277	527	22	sherry	sherry	PROPN
dti-2277	527	23	,	,	PUNCT
dti-2277	527	24	b.	b.	PROPN
dti-2277	527	25	and	and	CCONJ
dti-2277	527	26	bukrinsky	bukrinsky	PROPN
dti-2277	527	27	,	,	PUNCT
dti-2277	527	28	m.	m.	NOUN
dti-2277	527	29	2001	2001	NUM
dti-2277	527	30	.	.	PUNCT
dti-2277	528	1	cd147	cd147	PROPN
dti-2277	528	2	is	be	AUX
dti-2277	528	3	a	a	DET
dti-2277	528	4	signaling	signal	VERB
dti-2277	528	5	receptor	receptor	NOUN
dti-2277	528	6	for	for	ADP
dti-2277	528	7	cyclophilin	cyclophilin	PROPN
dti-2277	528	8	b.	b.	PROPN
dti-2277	528	9	biochem	biochem	PROPN
dti-2277	528	10	.	.	PUNCT
dti-2277	529	1	biophys	biophy	NOUN
dti-2277	529	2	.	.	PUNCT
dti-2277	530	1	res	re	NOUN
dti-2277	530	2	.	.	PUNCT
dti-2277	531	1	commun	commun	PROPN
dti-2277	531	2	.	.	PROPN
dti-2277	531	3	,	,	PUNCT
dti-2277	531	4	288:786–788	288:786–788	NUM
dti-2277	531	5	.	.	PUNCT
dti-2277	532	1	yurchenko	yurchenko	PROPN
dti-2277	532	2	,	,	PUNCT
dti-2277	532	3	v.	v.	PROPN
dti-2277	532	4	,	,	PUNCT
dti-2277	532	5	zybarth	zybarth	PROPN
dti-2277	532	6	,	,	PUNCT
dti-2277	532	7	g.	g.	PROPN
dti-2277	532	8	,	,	PUNCT
dti-2277	532	9	o’connor	o’connor	ADV
dti-2277	532	10	,	,	PUNCT
dti-2277	532	11	m.	m.	NOUN
dti-2277	532	12	,	,	PUNCT
dti-2277	532	13	dai	dai	PROPN
dti-2277	532	14	,	,	PUNCT
dti-2277	532	15	w.	w.	PROPN
dti-2277	532	16	w.	w.	PROPN
dti-2277	532	17	,	,	PUNCT
dti-2277	532	18	franchin	franchin	NOUN
dti-2277	532	19	,	,	PUNCT
dti-2277	532	20	g.	g.	PROPN
dti-2277	532	21	,	,	PUNCT
dti-2277	532	22	hao	hao	PROPN
dti-2277	532	23	,	,	PUNCT
dti-2277	532	24	t.	t.	PROPN
dti-2277	532	25	,	,	PUNCT
dti-2277	532	26	guo	guo	PROPN
dti-2277	532	27	,	,	PUNCT
dti-2277	532	28	h.	h.	PROPN
dti-2277	532	29	,	,	PUNCT
dti-2277	532	30	hung	hung	PROPN
dti-2277	532	31	,	,	PUNCT
dti-2277	532	32	h.	h.	PROPN
dti-2277	532	33	c.	c.	PROPN
dti-2277	532	34	,	,	PUNCT
dti-2277	532	35	toole	toole	PROPN
dti-2277	532	36	,	,	PUNCT
dti-2277	532	37	b.	b.	PROPN
dti-2277	532	38	and	and	CCONJ
dti-2277	532	39	gallay	gallay	NOUN
dti-2277	532	40	,	,	PUNCT
dti-2277	532	41	p.	p.	NOUN
dti-2277	532	42	et	et	NOUN
dti-2277	533	1	al	al	PROPN
dti-2277	533	2	.	.	PROPN
dti-2277	533	3	2002	2002	NUM
dti-2277	533	4	.	.	PUNCT
dti-2277	534	1	active	active	ADJ
dti-2277	534	2	site	site	NOUN
dti-2277	534	3	residues	residue	NOUN
dti-2277	534	4	of	of	ADP
dti-2277	534	5	cyclophilin	cyclophilin	PROPN
dti-2277	534	6	a	a	PRON
dti-2277	534	7	are	be	AUX
dti-2277	534	8	crucial	crucial	ADJ
dti-2277	534	9	for	for	ADP
dti-2277	534	10	its	its	PRON
dti-2277	534	11	signaling	signal	VERB
dti-2277	534	12	activity	activity	NOUN
dti-2277	534	13	via	via	ADP
dti-2277	534	14	cd147	cd147	PROPN
dti-2277	534	15	.	.	PUNCT
dti-2277	535	1	j.	j.	PROPN
dti-2277	535	2	biol	biol	PROPN
dti-2277	535	3	.	.	PUNCT
dti-2277	536	1	chem	chem	NOUN
dti-2277	536	2	.	.	PUNCT
dti-2277	537	1	277:22959–22965	277:22959–22965	NOUN
dti-2277	537	2	.	.	PUNCT
dti-2277	538	1	zander	zander	PROPN
dti-2277	538	2	,	,	PUNCT
dti-2277	538	3	k.	k.	PROPN
dti-2277	538	4	,	,	PUNCT
dti-2277	538	5	sherman	sherman	PROPN
dti-2277	538	6	,	,	PUNCT
dti-2277	538	7	m.p	m.p	PROPN
dti-2277	538	8	.	.	PROPN
dti-2277	538	9	,	,	PUNCT
dti-2277	538	10	tessmer	tessmer	NOUN
dti-2277	538	11	,	,	PUNCT
dti-2277	538	12	u.	u.	PROPN
dti-2277	538	13	,	,	PUNCT
dti-2277	538	14	bruns	brun	NOUN
dti-2277	538	15	,	,	PUNCT
dti-2277	538	16	k.	k.	PROPN
dti-2277	538	17	,	,	PUNCT
dti-2277	538	18	wray	wray	PROPN
dti-2277	538	19	,	,	PUNCT
dti-2277	538	20	v.	v.	PROPN
dti-2277	538	21	,	,	PUNCT
dti-2277	538	22	prechtel	prechtel	NOUN
dti-2277	538	23	,	,	PUNCT
dti-2277	538	24	a.	a.	NOUN
dti-2277	538	25	t.	t.	PROPN
dti-2277	538	26	,	,	PUNCT
dti-2277	538	27	schubert	schubert	PROPN
dti-2277	538	28	,	,	PUNCT
dti-2277	538	29	e.	e.	PROPN
dti-2277	538	30	,	,	PUNCT
dti-2277	538	31	henklein	henklein	PROPN
dti-2277	538	32	,	,	PUNCT
dti-2277	538	33	p.	p.	NOUN
dti-2277	538	34	,	,	PUNCT
dti-2277	538	35	luban	luban	PROPN
dti-2277	538	36	,	,	PUNCT
dti-2277	538	37	j.	j.	PROPN
dti-2277	538	38	and	and	CCONJ
dti-2277	538	39	neidleman	neidleman	PROPN
dti-2277	538	40	,	,	PUNCT
dti-2277	538	41	j.	j.	PROPN
dti-2277	538	42	et	et	PROPN
dti-2277	538	43	al	al	PROPN
dti-2277	538	44	.	.	PROPN
dti-2277	538	45	2003	2003	NUM
dti-2277	538	46	.	.	PUNCT
dti-2277	539	1	cyclophilin	cyclophilin	PROPN
dti-2277	539	2	a	a	PRON
dti-2277	539	3	interacts	interact	VERB
dti-2277	539	4	with	with	ADP
dti-2277	539	5	hiv-1	hiv-1	X
dti-2277	539	6	vpr	vpr	NOUN
dti-2277	539	7	and	and	CCONJ
dti-2277	539	8	is	be	AUX
dti-2277	539	9	required	require	VERB
dti-2277	539	10	for	for	ADP
dti-2277	539	11	its	its	PRON
dti-2277	539	12	functional	functional	ADJ
dti-2277	539	13	expression	expression	NOUN
dti-2277	539	14	.	.	PUNCT
dti-2277	540	1	j.	j.	PROPN
dti-2277	540	2	biol	biol	PROPN
dti-2277	540	3	.	.	PUNCT
dti-2277	541	1	chem	chem	PROPN
dti-2277	541	2	.	.	PUNCT
dti-2277	541	3	,	,	PUNCT
dti-2277	541	4	278:43202–43213	278:43202–43213	NUM
dti-2277	541	5	.	.	PUNCT
dti-2277	542	1	zeng	zeng	PROPN
dti-2277	542	2	,	,	PUNCT
dti-2277	542	3	l.	l.	PROPN
dti-2277	542	4	,	,	PUNCT
dti-2277	542	5	zhou	zhou	PROPN
dti-2277	542	6	,	,	PUNCT
dti-2277	542	7	z.	z.	PROPN
dti-2277	542	8	,	,	PUNCT
dti-2277	542	9	xu	xu	PROPN
dti-2277	542	10	,	,	PUNCT
dti-2277	542	11	j.	j.	PROPN
dti-2277	542	12	,	,	PUNCT
dti-2277	542	13	zhao	zhao	PROPN
dti-2277	542	14	,	,	PUNCT
dti-2277	542	15	w.	w.	PROPN
dti-2277	542	16	,	,	PUNCT
dti-2277	542	17	wang	wang	PROPN
dti-2277	542	18	,	,	PUNCT
dti-2277	542	19	w.	w.	PROPN
dti-2277	542	20	,	,	PUNCT
dti-2277	542	21	huang	huang	PROPN
dti-2277	542	22	,	,	PUNCT
dti-2277	542	23	y.	y.	PROPN
dti-2277	542	24	,	,	PUNCT
dti-2277	542	25	cheng	cheng	PROPN
dti-2277	542	26	,	,	PUNCT
dti-2277	542	27	c.	c.	PROPN
dti-2277	542	28	,	,	PUNCT
dti-2277	542	29	xu	xu	PROPN
dti-2277	542	30	,	,	PUNCT
dti-2277	542	31	m.	m.	NOUN
dti-2277	542	32	,	,	PUNCT
dti-2277	542	33	xie	xie	PROPN
dti-2277	542	34	,	,	PUNCT
dti-2277	542	35	y.	y.	PROPN
dti-2277	542	36	and	and	CCONJ
dti-2277	542	37	mao	mao	PROPN
dti-2277	542	38	,	,	PUNCT
dti-2277	542	39	y.	y.	PROPN
dti-2277	542	40	2001	2001	NUM
dti-2277	542	41	.	.	PUNCT
dti-2277	543	1	molecular	molecular	ADJ
dti-2277	543	2	cloning	cloning	NOUN
dti-2277	543	3	,	,	PUNCT
dti-2277	543	4	structure	structure	NOUN
dti-2277	543	5	and	and	CCONJ
dti-2277	543	6	expression	expression	NOUN
dti-2277	543	7	of	of	ADP
dti-2277	543	8	a	a	DET
dti-2277	543	9	novel	novel	ADJ
dti-2277	543	10	nuclear	nuclear	ADJ
dti-2277	543	11	rna	rna	NOUN
dti-2277	543	12	-	-	PUNCT
dti-2277	543	13	binding	bind	VERB
dti-2277	543	14	cyclophilin	cyclophilin	ADJ
dti-2277	543	15	-	-	PUNCT
dti-2277	543	16	like	like	ADJ
dti-2277	543	17	gene	gene	NOUN
dti-2277	543	18	(	(	PUNCT
dti-2277	543	19	ppil4	ppil4	VERB
dti-2277	543	20	)	)	PUNCT
dti-2277	543	21	from	from	ADP
dti-2277	543	22	human	human	ADJ
dti-2277	543	23	fetal	fetal	ADJ
dti-2277	543	24	brain	brain	NOUN
dti-2277	543	25	.	.	PUNCT
dti-2277	544	1	cytogenet	cytogenet	NOUN
dti-2277	544	2	.	.	PUNCT
dti-2277	545	1	cell	cell	NOUN
dti-2277	545	2	.	.	PUNCT
dti-2277	546	1	genet	genet	NOUN
dti-2277	546	2	.	.	PUNCT
dti-2277	546	3	,	,	PUNCT
dti-2277	546	4	95:43–47	95:43–47	NUM
dti-2277	546	5	.	.	PUNCT
dti-2277	547	1	zhou	zhou	PROPN
dti-2277	547	2	,	,	PUNCT
dti-2277	547	3	z.	z.	PROPN
dti-2277	547	4	,	,	PUNCT
dti-2277	547	5	ying	ying	PROPN
dti-2277	547	6	,	,	PUNCT
dti-2277	547	7	k.	k.	PROPN
dti-2277	547	8	,	,	PUNCT
dti-2277	547	9	dai	dai	PROPN
dti-2277	547	10	,	,	PUNCT
dti-2277	547	11	j.	j.	PROPN
dti-2277	547	12	,	,	PUNCT
dti-2277	547	13	tang	tang	PROPN
dti-2277	547	14	,	,	PUNCT
dti-2277	547	15	r.	r.	PROPN
dti-2277	547	16	,	,	PUNCT
dti-2277	547	17	wang	wang	PROPN
dti-2277	547	18	,	,	PUNCT
dti-2277	547	19	w.	w.	PROPN
dti-2277	547	20	,	,	PUNCT
dti-2277	547	21	huang	huang	PROPN
dti-2277	547	22	,	,	PUNCT
dti-2277	547	23	y.	y.	PROPN
dti-2277	547	24	,	,	PUNCT
dti-2277	547	25	zhao	zhao	PROPN
dti-2277	547	26	,	,	PUNCT
dti-2277	547	27	w.	w.	PROPN
dti-2277	547	28	,	,	PUNCT
dti-2277	547	29	xie	xie	PROPN
dti-2277	547	30	,	,	PUNCT
dti-2277	547	31	y.	y.	PROPN
dti-2277	547	32	and	and	CCONJ
dti-2277	547	33	mao	mao	PROPN
dti-2277	547	34	,	,	PUNCT
dti-2277	547	35	y.	y.	PROPN
dti-2277	547	36	2001	2001	NUM
dti-2277	547	37	.	.	PUNCT
dti-2277	548	1	molecular	molecular	ADJ
dti-2277	548	2	cloning	cloning	NOUN
dti-2277	548	3	and	and	CCONJ
dti-2277	548	4	characterization	characterization	NOUN
dti-2277	548	5	of	of	ADP
dti-2277	548	6	a	a	DET
dti-2277	548	7	novel	novel	ADJ
dti-2277	548	8	peptidylprolyl	peptidylprolyl	ADJ
dti-2277	548	9	isomerase	isomerase	NOUN
dti-2277	548	10	(	(	PUNCT
dti-2277	548	11	cyclophilin)-like	cyclophilin)-like	ADJ
dti-2277	548	12	gene	gene	NOUN
dti-2277	548	13	(	(	PUNCT
dti-2277	548	14	ppil3	ppil3	NOUN
dti-2277	548	15	)	)	PUNCT
dti-2277	548	16	from	from	ADP
dti-2277	548	17	human	human	ADJ
dti-2277	548	18	fetal	fetal	ADJ
dti-2277	548	19	brain	brain	NOUN
dti-2277	548	20	.	.	PUNCT
dti-2277	549	1	cytogenet	cytogenet	NOUN
dti-2277	549	2	.	.	PUNCT
dti-2277	550	1	cell	cell	NOUN
dti-2277	550	2	.	.	PUNCT
dti-2277	551	1	genet	genet	NOUN
dti-2277	551	2	.	.	PUNCT
dti-2277	551	3	,	,	PUNCT
dti-2277	551	4	92:231–236	92:231–236	NUM
dti-2277	551	5	.	.	PUNCT
dti-2277	551	6	drug	drug	NOUN
dti-2277	551	7	target	target	NOUN
dti-2277	551	8	insights	insight	NOUN
dti-2277	551	9	2007	2007	NUM
dti-2277	551	10	:	:	PUNCT
dti-2277	551	11	2	2	NUM