id	sid	tid	token	lemma	pos
dti-2520	1	1	dti	dti	PROPN
dti-2520	1	2	drug	drug	PROPN
dti-2520	1	3	target	target	NOUN
dti-2520	1	4	insights	insight	NOUN
dti-2520	1	5	issn	issn	VERB
dti-2520	1	6	1177	1177	NUM
dti-2520	1	7	-	-	SYM
dti-2520	1	8	3928	3928	NUM
dti-2520	1	9	www.aboutscience.eu/dti	www.aboutscience.eu/dti	NOUN
dti-2520	1	10	©	©	PROPN
dti-2520	1	11	2022	2022	NUM
dti-2520	1	12	the	the	DET
dti-2520	1	13	authors	author	NOUN
dti-2520	1	14	.	.	PUNCT
dti-2520	2	1	this	this	DET
dti-2520	2	2	article	article	NOUN
dti-2520	2	3	is	be	AUX
dti-2520	2	4	published	publish	VERB
dti-2520	2	5	by	by	ADP
dti-2520	2	6	aboutscience	aboutscience	NOUN
dti-2520	2	7	and	and	CCONJ
dti-2520	2	8	licensed	license	VERB
dti-2520	2	9	under	under	ADP
dti-2520	2	10	creative	creative	ADJ
dti-2520	2	11	commons	common	NOUN
dti-2520	2	12	attribution	attribution	NOUN
dti-2520	2	13	-	-	PUNCT
dti-2520	2	14	noncommercial	noncommercial	ADJ
dti-2520	2	15	4.0	4.0	NUM
dti-2520	2	16	international	international	NOUN
dti-2520	2	17	(	(	PUNCT
dti-2520	2	18	cc	cc	NOUN
dti-2520	2	19	by	by	ADP
dti-2520	2	20	-	-	PUNCT
dti-2520	2	21	nc	nc	PROPN
dti-2520	2	22	4.0	4.0	NUM
dti-2520	2	23	)	)	PUNCT
dti-2520	2	24	.	.	PUNCT
dti-2520	3	1	commercial	commercial	ADJ
dti-2520	3	2	use	use	NOUN
dti-2520	3	3	is	be	AUX
dti-2520	3	4	not	not	PART
dti-2520	3	5	permitted	permit	VERB
dti-2520	3	6	and	and	CCONJ
dti-2520	3	7	is	be	AUX
dti-2520	3	8	subject	subject	ADJ
dti-2520	3	9	to	to	ADP
dti-2520	3	10	publisher	publisher	NOUN
dti-2520	3	11	’s	’s	PART
dti-2520	3	12	permissions	permission	NOUN
dti-2520	3	13	.	.	PUNCT
dti-2520	4	1	full	full	ADJ
dti-2520	4	2	information	information	NOUN
dti-2520	4	3	is	be	AUX
dti-2520	4	4	available	available	ADJ
dti-2520	4	5	at	at	ADP
dti-2520	4	6	www.aboutscience.eu	www.aboutscience.eu	PROPN
dti-2520	4	7	drug	drug	NOUN
dti-2520	4	8	target	target	NOUN
dti-2520	4	9	insights	insight	NOUN
dti-2520	4	10	2022	2022	NUM
dti-2520	4	11	;	;	PUNCT
dti-2520	4	12	16	16	NUM
dti-2520	4	13	:	:	SYM
dti-2520	4	14	81	81	NUM
dti-2520	4	15	-	-	SYM
dti-2520	4	16	87	87	NUM
dti-2520	4	17	issn	issn	PROPN
dti-2520	4	18	1177	1177	NUM
dti-2520	4	19	-	-	SYM
dti-2520	4	20	3928	3928	NUM
dti-2520	4	21	|	|	ADV
dti-2520	4	22	doi	doi	NOUN
dti-2520	4	23	:	:	PUNCT
dti-2520	4	24	10.33393	10.33393	NUM
dti-2520	4	25	/	/	SYM
dti-2520	4	26	dti.2022.2520	dti.2022.2520	ADJ
dti-2520	4	27	review	review	NOUN
dti-2520	4	28	antibiotic	antibiotic	ADJ
dti-2520	4	29	-	-	PUNCT
dti-2520	4	30	resistant	resistant	ADJ
dti-2520	4	31	bacteria	bacteria	NOUN
dti-2520	4	32	originating	originate	VERB
dti-2520	4	33	from	from	ADP
dti-2520	4	34	the	the	DET
dti-2520	4	35	gut	gut	NOUN
dti-2520	4	36	may	may	AUX
dti-2520	4	37	modulate	modulate	VERB
dti-2520	4	38	the	the	DET
dti-2520	4	39	mucosal	mucosal	ADJ
dti-2520	4	40	immune	immune	ADJ
dti-2520	4	41	response	response	NOUN
dti-2520	4	42	during	during	ADP
dti-2520	4	43	sepsis	sepsis	NOUN
dti-2520	4	44	and	and	CCONJ
dti-2520	4	45	septic	septic	ADJ
dti-2520	4	46	shock	shock	NOUN
dti-2520	4	47	swinder	swinder	NOUN
dti-2520	4	48	jeet	jeet	PROPN
dti-2520	4	49	singh	singh	PROPN
dti-2520	4	50	kalra1	kalra1	PROPN
dti-2520	4	51	,	,	PUNCT
dti-2520	4	52	hari	hari	PROPN
dti-2520	4	53	shankar2	shankar2	PROPN
dti-2520	4	54	,	,	PUNCT
dti-2520	4	55	nasim	nasim	PROPN
dti-2520	4	56	mansoori3	mansoori3	PROPN
dti-2520	4	57	,	,	PUNCT
dti-2520	4	58	dablu	dablu	PROPN
dti-2520	4	59	lal	lal	PROPN
dti-2520	4	60	gupta4	gupta4	PROPN
dti-2520	4	61	1d.a	1d.a	NUM
dti-2520	4	62	-	-	PUNCT
dti-2520	4	63	v	v	NOUN
dti-2520	4	64	college	college	NOUN
dti-2520	4	65	kanpur	kanpur	PROPN
dti-2520	4	66	,	,	PUNCT
dti-2520	4	67	uttar	uttar	PROPN
dti-2520	4	68	pradesh	pradesh	PROPN
dti-2520	4	69	india	india	PROPN
dti-2520	4	70	2indian	2indian	PROPN
dti-2520	4	71	council	council	NOUN
dti-2520	4	72	of	of	ADP
dti-2520	4	73	medical	medical	ADJ
dti-2520	4	74	research	research	NOUN
dti-2520	4	75	(	(	PUNCT
dti-2520	4	76	icmr	icmr	PROPN
dti-2520	4	77	)	)	PUNCT
dti-2520	4	78	,	,	PUNCT
dti-2520	4	79	new	new	PROPN
dti-2520	4	80	delhi	delhi	PROPN
dti-2520	4	81	india	india	PROPN
dti-2520	4	82	3all	3all	PROPN
dti-2520	4	83	india	india	PROPN
dti-2520	4	84	institute	institute	PROPN
dti-2520	4	85	of	of	ADP
dti-2520	4	86	medical	medical	PROPN
dti-2520	4	87	sciences	sciences	PROPN
dti-2520	4	88	(	(	PUNCT
dti-2520	4	89	aiims	aiims	PROPN
dti-2520	4	90	)	)	PUNCT
dti-2520	4	91	,	,	PUNCT
dti-2520	4	92	new	new	PROPN
dti-2520	4	93	delhi	delhi	PROPN
dti-2520	4	94	india	india	PROPN
dti-2520	4	95	4all	4all	PROPN
dti-2520	4	96	india	india	PROPN
dti-2520	4	97	institute	institute	PROPN
dti-2520	4	98	of	of	ADP
dti-2520	4	99	medical	medical	PROPN
dti-2520	4	100	sciences	sciences	PROPN
dti-2520	4	101	(	(	PUNCT
dti-2520	4	102	aiims	aiims	PROPN
dti-2520	4	103	)	)	PUNCT
dti-2520	4	104	,	,	PUNCT
dti-2520	4	105	raipur	raipur	NOUN
dti-2520	4	106	,	,	PUNCT
dti-2520	4	107	chhattisgarh	chhattisgarh	NOUN
dti-2520	4	108	india	india	PROPN
dti-2520	4	109	abstract	abstract	ADJ
dti-2520	4	110	the	the	DET
dti-2520	4	111	enrichment	enrichment	NOUN
dti-2520	4	112	and	and	CCONJ
dti-2520	4	113	diversity	diversity	NOUN
dti-2520	4	114	of	of	ADP
dti-2520	4	115	gut	gut	NOUN
dti-2520	4	116	microbiota	microbiota	NOUN
dti-2520	4	117	play	play	VERB
dti-2520	4	118	an	an	DET
dti-2520	4	119	important	important	ADJ
dti-2520	4	120	role	role	NOUN
dti-2520	4	121	in	in	ADP
dti-2520	4	122	sepsis	sepsis	NOUN
dti-2520	4	123	,	,	PUNCT
dti-2520	4	124	but	but	CCONJ
dti-2520	4	125	the	the	DET
dti-2520	4	126	role	role	NOUN
dti-2520	4	127	of	of	ADP
dti-2520	4	128	gut	gut	ADJ
dti-2520	4	129	microbiota	microbiota	NOUN
dti-2520	4	130	composition	composition	NOUN
dti-2520	4	131	and	and	CCONJ
dti-2520	4	132	early	early	ADJ
dti-2520	4	133	-	-	PUNCT
dti-2520	4	134	life	life	NOUN
dti-2520	4	135	colonization	colonization	NOUN
dti-2520	4	136	in	in	ADP
dti-2520	4	137	sepsis	sepsis	NOUN
dti-2520	4	138	and	and	CCONJ
dti-2520	4	139	septic	septic	ADJ
dti-2520	4	140	shock	shock	NOUN
dti-2520	4	141	has	have	AUX
dti-2520	4	142	not	not	PART
dti-2520	4	143	yet	yet	ADV
dti-2520	4	144	been	be	AUX
dti-2520	4	145	characterized	characterize	VERB
dti-2520	4	146	.	.	PUNCT
dti-2520	5	1	the	the	DET
dti-2520	5	2	impact	impact	NOUN
dti-2520	5	3	of	of	ADP
dti-2520	5	4	gut	gut	ADJ
dti-2520	5	5	microbiota	microbiota	NOUN
dti-2520	5	6	diversity	diversity	NOUN
dti-2520	5	7	on	on	ADP
dti-2520	5	8	host	host	NOUN
dti-2520	5	9	immunological	immunological	ADJ
dti-2520	5	10	disorders	disorder	NOUN
dti-2520	5	11	and	and	CCONJ
dti-2520	5	12	future	future	ADJ
dti-2520	5	13	treatments	treatment	NOUN
dti-2520	5	14	of	of	ADP
dti-2520	5	15	inflammatory	inflammatory	ADJ
dti-2520	5	16	diseases	disease	NOUN
dti-2520	5	17	are	be	AUX
dti-2520	5	18	not	not	PART
dti-2520	5	19	yet	yet	ADV
dti-2520	5	20	fully	fully	ADV
dti-2520	5	21	elucidated	elucidated	ADJ
dti-2520	5	22	.	.	PUNCT
dti-2520	6	1	further	far	ADV
dti-2520	6	2	,	,	PUNCT
dti-2520	6	3	the	the	DET
dti-2520	6	4	association	association	NOUN
dti-2520	6	5	between	between	ADP
dti-2520	6	6	the	the	DET
dti-2520	6	7	microbiota	microbiota	NOUN
dti-2520	6	8	and	and	CCONJ
dti-2520	6	9	immune	immune	ADJ
dti-2520	6	10	development	development	NOUN
dti-2520	6	11	in	in	ADP
dti-2520	6	12	sepsis	sepsis	NOUN
dti-2520	6	13	remains	remain	VERB
dti-2520	6	14	unknown	unknown	ADJ
dti-2520	6	15	,	,	PUNCT
dti-2520	6	16	and	and	CCONJ
dti-2520	6	17	the	the	DET
dti-2520	6	18	underlying	underlying	ADJ
dti-2520	6	19	mechanisms	mechanism	NOUN
dti-2520	6	20	are	be	AUX
dti-2520	6	21	not	not	PART
dti-2520	6	22	well	well	ADV
dti-2520	6	23	understood	understand	VERB
dti-2520	6	24	.	.	PUNCT
dti-2520	7	1	the	the	DET
dti-2520	7	2	altered	alter	VERB
dti-2520	7	3	composition	composition	NOUN
dti-2520	7	4	of	of	ADP
dti-2520	7	5	gut	gut	NOUN
dti-2520	7	6	microbiota	microbiota	NOUN
dti-2520	7	7	during	during	ADP
dti-2520	7	8	sepsis	sepsis	NOUN
dti-2520	7	9	is	be	AUX
dti-2520	7	10	profoundly	profoundly	ADV
dti-2520	7	11	associated	associate	VERB
dti-2520	7	12	with	with	ADP
dti-2520	7	13	a	a	DET
dti-2520	7	14	loss	loss	NOUN
dti-2520	7	15	of	of	ADP
dti-2520	7	16	commensal	commensal	ADJ
dti-2520	7	17	bacteria	bacteria	NOUN
dti-2520	7	18	and	and	CCONJ
dti-2520	7	19	an	an	DET
dti-2520	7	20	overgrowth	overgrowth	NOUN
dti-2520	7	21	of	of	ADP
dti-2520	7	22	potentially	potentially	ADV
dti-2520	7	23	pathogenic	pathogenic	ADJ
dti-2520	7	24	bacteria	bacteria	NOUN
dti-2520	7	25	,	,	PUNCT
dti-2520	7	26	especially	especially	ADV
dti-2520	7	27	amr	amr	ADJ
dti-2520	7	28	bacteria	bacteria	NOUN
dti-2520	7	29	.	.	PUNCT
dti-2520	8	1	disruptions	disruption	NOUN
dti-2520	8	2	of	of	ADP
dti-2520	8	3	gut	gut	ADJ
dti-2520	8	4	microbiota	microbiota	NOUN
dti-2520	8	5	diversity	diversity	NOUN
dti-2520	8	6	are	be	AUX
dti-2520	8	7	directly	directly	ADV
dti-2520	8	8	associated	associate	VERB
dti-2520	8	9	with	with	ADP
dti-2520	8	10	susceptibility	susceptibility	NOUN
dti-2520	8	11	to	to	ADP
dti-2520	8	12	sepsis	sepsis	NOUN
dti-2520	8	13	and	and	CCONJ
dti-2520	8	14	a	a	DET
dti-2520	8	15	higher	high	ADJ
dti-2520	8	16	risk	risk	NOUN
dti-2520	8	17	of	of	ADP
dti-2520	8	18	adverse	adverse	ADJ
dti-2520	8	19	outcomes	outcome	NOUN
dti-2520	8	20	.	.	PUNCT
dti-2520	9	1	several	several	ADJ
dti-2520	9	2	studies	study	NOUN
dti-2520	9	3	have	have	AUX
dti-2520	9	4	confirmed	confirm	VERB
dti-2520	9	5	that	that	SCONJ
dti-2520	9	6	a	a	DET
dti-2520	9	7	mutual	mutual	ADJ
dti-2520	9	8	association	association	NOUN
dti-2520	9	9	between	between	ADP
dti-2520	9	10	gut	gut	NOUN
dti-2520	9	11	microbiota	microbiota	NOUN
dti-2520	9	12	and	and	CCONJ
dti-2520	9	13	the	the	DET
dti-2520	9	14	host	host	NOUN
dti-2520	9	15	is	be	AUX
dti-2520	9	16	important	important	ADJ
dti-2520	9	17	for	for	ADP
dti-2520	9	18	the	the	DET
dti-2520	9	19	metabolism	metabolism	NOUN
dti-2520	9	20	of	of	ADP
dti-2520	9	21	essential	essential	ADJ
dti-2520	9	22	nutrients	nutrient	NOUN
dti-2520	9	23	for	for	ADP
dti-2520	9	24	the	the	DET
dti-2520	9	25	organism	organism	NOUN
dti-2520	9	26	,	,	PUNCT
dti-2520	9	27	for	for	ADP
dti-2520	9	28	gut	gut	NOUN
dti-2520	9	29	development	development	NOUN
dti-2520	9	30	,	,	PUNCT
dti-2520	9	31	and	and	CCONJ
dti-2520	9	32	for	for	ADP
dti-2520	9	33	the	the	DET
dti-2520	9	34	maturation	maturation	NOUN
dti-2520	9	35	and	and	CCONJ
dti-2520	9	36	development	development	NOUN
dti-2520	9	37	of	of	ADP
dti-2520	9	38	a	a	DET
dti-2520	9	39	fully	fully	ADV
dti-2520	9	40	functional	functional	ADJ
dti-2520	9	41	immune	immune	ADJ
dti-2520	9	42	system	system	NOUN
dti-2520	9	43	.	.	PUNCT
dti-2520	10	1	therefore	therefore	ADV
dti-2520	10	2	,	,	PUNCT
dti-2520	10	3	understanding	understand	VERB
dti-2520	10	4	the	the	DET
dti-2520	10	5	gut	gut	ADJ
dti-2520	10	6	microbiota	microbiota	NOUN
dti-2520	10	7	diversity	diversity	NOUN
dti-2520	10	8	,	,	PUNCT
dti-2520	10	9	composition	composition	NOUN
dti-2520	10	10	,	,	PUNCT
dti-2520	10	11	and	and	CCONJ
dti-2520	10	12	function	function	NOUN
dti-2520	10	13	during	during	ADP
dti-2520	10	14	various	various	ADJ
dti-2520	10	15	inflammatory	inflammatory	ADJ
dti-2520	10	16	conditions	condition	NOUN
dti-2520	10	17	and	and	CCONJ
dti-2520	10	18	sepsis	sepsis	NOUN
dti-2520	10	19	may	may	AUX
dti-2520	10	20	provide	provide	VERB
dti-2520	10	21	a	a	DET
dti-2520	10	22	comprehensive	comprehensive	ADJ
dti-2520	10	23	knowledge	knowledge	NOUN
dti-2520	10	24	of	of	ADP
dti-2520	10	25	the	the	DET
dti-2520	10	26	mechanisms	mechanism	NOUN
dti-2520	10	27	behind	behind	ADP
dti-2520	10	28	the	the	DET
dti-2520	10	29	pathogenesis	pathogenesis	NOUN
dti-2520	10	30	of	of	ADP
dti-2520	10	31	gut	gut	NOUN
dti-2520	10	32	-	-	PUNCT
dti-2520	10	33	derived	derive	VERB
dti-2520	10	34	infection	infection	NOUN
dti-2520	10	35	in	in	ADP
dti-2520	10	36	diseases	disease	NOUN
dti-2520	10	37	and	and	CCONJ
dti-2520	10	38	the	the	DET
dti-2520	10	39	design	design	NOUN
dti-2520	10	40	of	of	ADP
dti-2520	10	41	new	new	ADJ
dti-2520	10	42	treatment	treatment	NOUN
dti-2520	10	43	options	option	NOUN
dti-2520	10	44	(	(	PUNCT
dti-2520	10	45	e.g.	e.g.	ADV
dti-2520	10	46	,	,	PUNCT
dti-2520	10	47	probiotics	probiotic	NOUN
dti-2520	10	48	or	or	CCONJ
dti-2520	10	49	fecal	fecal	ADJ
dti-2520	10	50	microbiota	microbiota	NOUN
dti-2520	10	51	transplantation	transplantation	NOUN
dti-2520	10	52	)	)	PUNCT
dti-2520	10	53	.	.	PUNCT
dti-2520	11	1	emerging	emerge	VERB
dti-2520	11	2	evidence	evidence	NOUN
dti-2520	11	3	displays	display	VERB
dti-2520	11	4	an	an	DET
dti-2520	11	5	important	important	ADJ
dti-2520	11	6	role	role	NOUN
dti-2520	11	7	of	of	ADP
dti-2520	11	8	gut	gut	NOUN
dti-2520	11	9	microbiota	microbiota	NOUN
dti-2520	11	10	and	and	CCONJ
dti-2520	11	11	their	their	PRON
dti-2520	11	12	derived	derive	VERB
dti-2520	11	13	metabolites	metabolite	NOUN
dti-2520	11	14	in	in	ADP
dti-2520	11	15	modulating	modulate	VERB
dti-2520	11	16	the	the	DET
dti-2520	11	17	host	host	NOUN
dti-2520	11	18	mucosal	mucosal	NOUN
dti-2520	11	19	immune	immune	ADJ
dti-2520	11	20	response	response	NOUN
dti-2520	11	21	and	and	CCONJ
dti-2520	11	22	determining	determine	VERB
dti-2520	11	23	the	the	DET
dti-2520	11	24	susceptibility	susceptibility	NOUN
dti-2520	11	25	to	to	PART
dti-2520	11	26	,	,	PUNCT
dti-2520	11	27	as	as	ADV
dti-2520	11	28	well	well	ADV
dti-2520	11	29	as	as	ADP
dti-2520	11	30	outcomes	outcome	NOUN
dti-2520	11	31	of	of	ADP
dti-2520	11	32	sepsis	sepsis	NOUN
dti-2520	11	33	.	.	PUNCT
dti-2520	12	1	keywords	keyword	NOUN
dti-2520	12	2	:	:	PUNCT
dti-2520	12	3	immune	immune	ADJ
dti-2520	12	4	response	response	NOUN
dti-2520	12	5	,	,	PUNCT
dti-2520	12	6	inflammation	inflammation	NOUN
dti-2520	12	7	,	,	PUNCT
dti-2520	12	8	metabolites	metabolite	NOUN
dti-2520	12	9	,	,	PUNCT
dti-2520	12	10	microbiota	microbiota	NOUN
dti-2520	12	11	,	,	PUNCT
dti-2520	12	12	sepsis	sepsis	NOUN
dti-2520	12	13	received	receive	VERB
dti-2520	12	14	:	:	PUNCT
dti-2520	12	15	november	november	PROPN
dti-2520	12	16	16	16	NUM
dti-2520	12	17	,	,	PUNCT
dti-2520	12	18	2022	2022	NUM
dti-2520	12	19	accepted	accept	VERB
dti-2520	12	20	:	:	PUNCT
dti-2520	12	21	december	december	PROPN
dti-2520	12	22	30	30	NUM
dti-2520	12	23	,	,	PUNCT
dti-2520	12	24	2022	2022	NUM
dti-2520	12	25	published	publish	VERB
dti-2520	12	26	online	online	ADV
dti-2520	12	27	:	:	PUNCT
dti-2520	12	28	december	december	PROPN
dti-2520	12	29	31	31	NUM
dti-2520	12	30	,	,	PUNCT
dti-2520	12	31	2022	2022	NUM
dti-2520	12	32	corresponding	correspond	VERB
dti-2520	12	33	author	author	NOUN
dti-2520	12	34	:	:	PUNCT
dti-2520	12	35	dr	dr	PROPN
dti-2520	12	36	.	.	PROPN
dti-2520	12	37	dablu	dablu	PROPN
dti-2520	12	38	lal	lal	PROPN
dti-2520	12	39	gupta	gupta	PROPN
dti-2520	12	40	assistant	assistant	PROPN
dti-2520	12	41	professor	professor	PROPN
dti-2520	12	42	department	department	PROPN
dti-2520	12	43	of	of	ADP
dti-2520	12	44	biochemistry	biochemistry	PROPN
dti-2520	12	45	all	all	DET
dti-2520	12	46	india	india	PROPN
dti-2520	12	47	institute	institute	PROPN
dti-2520	12	48	of	of	ADP
dti-2520	12	49	medical	medical	PROPN
dti-2520	12	50	sciences	sciences	PROPN
dti-2520	12	51	(	(	PUNCT
dti-2520	12	52	aiims	aiims	PROPN
dti-2520	12	53	)	)	PUNCT
dti-2520	12	54	raipur	raipur	NOUN
dti-2520	12	55	,	,	PUNCT
dti-2520	12	56	chhattisgarh	chhattisgarh	NOUN
dti-2520	12	57	india	india	PROPN
dti-2520	12	58	dablugupta10@gmail.com	dablugupta10@gmail.com	PROPN
dti-2520	12	59	illness	illness	NOUN
dti-2520	12	60	,	,	PUNCT
dti-2520	12	61	and	and	CCONJ
dti-2520	12	62	death	death	NOUN
dti-2520	12	63	(	(	PUNCT
dti-2520	12	64	2	2	NUM
dti-2520	12	65	)	)	PUNCT
dti-2520	12	66	.	.	PUNCT
dti-2520	13	1	resistant	resistant	ADJ
dti-2520	13	2	infections	infection	NOUN
dti-2520	13	3	can	can	AUX
dti-2520	13	4	be	be	AUX
dti-2520	13	5	difficult	difficult	ADJ
dti-2520	13	6	,	,	PUNCT
dti-2520	13	7	and	and	CCONJ
dti-2520	13	8	sometimes	sometimes	ADV
dti-2520	13	9	impossible	impossible	ADJ
dti-2520	13	10	,	,	PUNCT
dti-2520	13	11	to	to	PART
dti-2520	13	12	treat	treat	VERB
dti-2520	13	13	.	.	PUNCT
dti-2520	14	1	when	when	SCONJ
dti-2520	14	2	the	the	DET
dti-2520	14	3	microorganisms	microorganism	NOUN
dti-2520	14	4	become	become	VERB
dti-2520	14	5	resistant	resistant	ADJ
dti-2520	14	6	to	to	ADP
dti-2520	14	7	most	most	ADJ
dti-2520	14	8	of	of	ADP
dti-2520	14	9	the	the	DET
dti-2520	14	10	antibiotics	antibiotic	NOUN
dti-2520	14	11	and	and	CCONJ
dti-2520	14	12	other	other	ADJ
dti-2520	14	13	medications	medication	NOUN
dti-2520	14	14	commonly	commonly	ADV
dti-2520	14	15	used	use	VERB
dti-2520	14	16	to	to	PART
dti-2520	14	17	treat	treat	VERB
dti-2520	14	18	the	the	DET
dti-2520	14	19	infections	infection	NOUN
dti-2520	14	20	they	they	PRON
dti-2520	14	21	cause	cause	VERB
dti-2520	14	22	,	,	PUNCT
dti-2520	14	23	they	they	PRON
dti-2520	14	24	are	be	AUX
dti-2520	14	25	often	often	ADV
dti-2520	14	26	referred	refer	VERB
dti-2520	14	27	to	to	ADP
dti-2520	14	28	as	as	ADP
dti-2520	14	29	“	"	PUNCT
dti-2520	14	30	superbugs	superbug	NOUN
dti-2520	14	31	.	.	PUNCT
dti-2520	14	32	”	"	PUNCT
dti-2520	15	1	amr	amr	NOUN
dti-2520	15	2	is	be	AUX
dti-2520	15	3	considered	consider	VERB
dti-2520	15	4	one	one	NUM
dti-2520	15	5	of	of	ADP
dti-2520	15	6	the	the	DET
dti-2520	15	7	leading	lead	VERB
dti-2520	15	8	public	public	ADJ
dti-2520	15	9	health	health	NOUN
dti-2520	15	10	threats	threat	NOUN
dti-2520	15	11	of	of	ADP
dti-2520	15	12	the	the	DET
dti-2520	15	13	21st	21st	ADJ
dti-2520	15	14	century	century	NOUN
dti-2520	15	15	(	(	PUNCT
dti-2520	15	16	3	3	NUM
dti-2520	15	17	)	)	PUNCT
dti-2520	15	18	.	.	PUNCT
dti-2520	16	1	about	about	ADV
dti-2520	16	2	700,000	700,000	NUM
dti-2520	16	3	deaths	death	NOUN
dti-2520	16	4	have	have	AUX
dti-2520	16	5	been	be	AUX
dti-2520	16	6	reported	report	VERB
dti-2520	16	7	due	due	ADJ
dti-2520	16	8	to	to	ADP
dti-2520	16	9	drug	drug	NOUN
dti-2520	16	10	-	-	PUNCT
dti-2520	16	11	resistant	resistant	ADJ
dti-2520	16	12	infections	infection	NOUN
dti-2520	16	13	(	(	PUNCT
dti-2520	16	14	4	4	NUM
dti-2520	16	15	)	)	PUNCT
dti-2520	16	16	.	.	PUNCT
dti-2520	17	1	about	about	ADV
dti-2520	17	2	2.8	2.8	NUM
dti-2520	17	3	million	million	NUM
dti-2520	17	4	people	people	NOUN
dti-2520	17	5	suffer	suffer	VERB
dti-2520	17	6	from	from	ADP
dti-2520	17	7	acquired	acquire	VERB
dti-2520	17	8	drug	drug	NOUN
dti-2520	17	9	-	-	PUNCT
dti-2520	17	10	resistant	resistant	ADJ
dti-2520	17	11	infections	infection	NOUN
dti-2520	17	12	across	across	ADP
dti-2520	17	13	the	the	DET
dti-2520	17	14	globe	globe	NOUN
dti-2520	17	15	and	and	CCONJ
dti-2520	17	16	35,000	35,000	NUM
dti-2520	17	17	patients	patient	NOUN
dti-2520	17	18	die	die	VERB
dti-2520	17	19	annually	annually	ADV
dti-2520	17	20	in	in	ADP
dti-2520	17	21	the	the	DET
dti-2520	17	22	united	united	PROPN
dti-2520	17	23	states	states	PROPN
dti-2520	17	24	due	due	ADP
dti-2520	17	25	to	to	ADP
dti-2520	17	26	infections	infection	NOUN
dti-2520	17	27	alone	alone	ADV
dti-2520	17	28	(	(	PUNCT
dti-2520	17	29	5	5	NUM
dti-2520	17	30	)	)	PUNCT
dti-2520	17	31	.	.	PUNCT
dti-2520	18	1	it	it	PRON
dti-2520	18	2	is	be	AUX
dti-2520	18	3	responsible	responsible	ADJ
dti-2520	18	4	for	for	ADP
dti-2520	18	5	an	an	DET
dti-2520	18	6	estimated	estimate	VERB
dti-2520	18	7	33,000	33,000	NUM
dti-2520	18	8	deaths	death	NOUN
dti-2520	18	9	per	per	ADP
dti-2520	18	10	year	year	NOUN
dti-2520	18	11	in	in	ADP
dti-2520	18	12	the	the	DET
dti-2520	18	13	european	european	PROPN
dti-2520	18	14	union	union	PROPN
dti-2520	18	15	(	(	PUNCT
dti-2520	18	16	eu	eu	PROPN
dti-2520	18	17	)	)	PUNCT
dti-2520	18	18	(	(	PUNCT
dti-2520	18	19	6	6	NUM
dti-2520	18	20	)	)	PUNCT
dti-2520	18	21	.	.	PUNCT
dti-2520	19	1	in	in	ADP
dti-2520	19	2	2019	2019	NUM
dti-2520	19	3	,	,	PUNCT
dti-2520	19	4	the	the	DET
dti-2520	19	5	world	world	PROPN
dti-2520	19	6	health	health	NOUN
dti-2520	19	7	organization	organization	NOUN
dti-2520	19	8	(	(	PUNCT
dti-2520	19	9	who	who	PRON
dti-2520	19	10	)	)	PUNCT
dti-2520	19	11	reported	report	VERB
dti-2520	19	12	that	that	SCONJ
dti-2520	19	13	,	,	PUNCT
dti-2520	19	14	if	if	SCONJ
dti-2520	19	15	left	leave	VERB
dti-2520	19	16	unchecked	unchecked	ADJ
dti-2520	19	17	,	,	PUNCT
dti-2520	19	18	the	the	DET
dti-2520	19	19	anticipated	anticipate	VERB
dti-2520	19	20	deaths	death	NOUN
dti-2520	19	21	due	due	ADJ
dti-2520	19	22	to	to	ADP
dti-2520	19	23	amr	amr	PROPN
dti-2520	19	24	would	would	AUX
dti-2520	19	25	rise	rise	VERB
dti-2520	19	26	to	to	ADP
dti-2520	19	27	10	10	NUM
dti-2520	19	28	million	million	NUM
dti-2520	19	29	by	by	ADP
dti-2520	19	30	2050	2050	NUM
dti-2520	19	31	(	(	PUNCT
dti-2520	19	32	5	5	NUM
dti-2520	19	33	)	)	PUNCT
dti-2520	19	34	.	.	PUNCT
dti-2520	20	1	these	these	DET
dti-2520	20	2	infections	infection	NOUN
dti-2520	20	3	have	have	VERB
dti-2520	20	4	significant	significant	ADJ
dti-2520	20	5	economic	economic	ADJ
dti-2520	20	6	and	and	CCONJ
dti-2520	20	7	human	human	ADJ
dti-2520	20	8	costs	cost	NOUN
dti-2520	20	9	.	.	PUNCT
dti-2520	21	1	economic	economic	ADJ
dti-2520	21	2	projections	projection	NOUN
dti-2520	21	3	suggest	suggest	VERB
dti-2520	21	4	that	that	SCONJ
dti-2520	21	5	by	by	ADP
dti-2520	21	6	2050	2050	NUM
dti-2520	21	7	,	,	PUNCT
dti-2520	21	8	the	the	DET
dti-2520	21	9	economic	economic	ADJ
dti-2520	21	10	costs	cost	NOUN
dti-2520	21	11	of	of	ADP
dti-2520	21	12	healthcare	healthcare	NOUN
dti-2520	21	13	-	-	PUNCT
dti-2520	21	14	associated	associate	VERB
dti-2520	21	15	infections	infection	NOUN
dti-2520	21	16	(	(	PUNCT
dti-2520	21	17	hais	hais	PROPN
dti-2520	21	18	)	)	PUNCT
dti-2520	21	19	to	to	ADP
dti-2520	21	20	the	the	DET
dti-2520	21	21	us	us	PROPN
dti-2520	21	22	healthcare	healthcare	NOUN
dti-2520	21	23	system	system	NOUN
dti-2520	21	24	will	will	AUX
dti-2520	21	25	range	range	VERB
dti-2520	21	26	from	from	ADP
dti-2520	21	27	28	28	NUM
dti-2520	21	28	to	to	PART
dti-2520	21	29	45	45	NUM
dti-2520	21	30	billion	billion	NUM
dti-2520	21	31	dollars	dollar	NOUN
dti-2520	21	32	per	per	ADP
dti-2520	21	33	year	year	NOUN
dti-2520	21	34	(	(	PUNCT
dti-2520	21	35	7	7	NUM
dti-2520	21	36	)	)	PUNCT
dti-2520	21	37	.	.	PUNCT
dti-2520	22	1	further	far	ADV
dti-2520	22	2	,	,	PUNCT
dti-2520	22	3	recent	recent	ADJ
dti-2520	22	4	data	datum	NOUN
dti-2520	22	5	released	release	VERB
dti-2520	22	6	by	by	ADP
dti-2520	22	7	the	the	DET
dti-2520	22	8	uk	uk	PROPN
dti-2520	22	9	government	government	NOUN
dti-2520	22	10	argued	argue	VERB
dti-2520	22	11	that	that	SCONJ
dti-2520	22	12	amr	amr	PROPN
dti-2520	22	13	could	could	AUX
dti-2520	22	14	kill	kill	VERB
dti-2520	22	15	10	10	NUM
dti-2520	22	16	million	million	NUM
dti-2520	22	17	people	people	NOUN
dti-2520	22	18	per	per	ADP
dti-2520	22	19	year	year	NOUN
dti-2520	22	20	by	by	ADP
dti-2520	22	21	2050	2050	NUM
dti-2520	22	22	(	(	PUNCT
dti-2520	22	23	8)	8)	NUM
dti-2520	22	24	.	.	PUNCT
dti-2520	23	1	the	the	DET
dti-2520	23	2	who	who	PRON
dti-2520	23	3	and	and	CCONJ
dti-2520	23	4	numerous	numerous	ADJ
dti-2520	23	5	other	other	ADJ
dti-2520	23	6	introduction	introduction	NOUN
dti-2520	23	7	antimicrobial	antimicrobial	ADJ
dti-2520	23	8	resistance	resistance	NOUN
dti-2520	23	9	(	(	PUNCT
dti-2520	23	10	amr	amr	NOUN
dti-2520	23	11	)	)	PUNCT
dti-2520	23	12	also	also	ADV
dti-2520	23	13	known	know	VERB
dti-2520	23	14	as	as	ADP
dti-2520	23	15	drug	drug	NOUN
dti-2520	23	16	resistance	resistance	NOUN
dti-2520	23	17	,	,	PUNCT
dti-2520	23	18	is	be	AUX
dti-2520	23	19	a	a	DET
dti-2520	23	20	naturally	naturally	ADV
dti-2520	23	21	occurring	occur	VERB
dti-2520	23	22	process	process	NOUN
dti-2520	23	23	that	that	PRON
dti-2520	23	24	happens	happen	VERB
dti-2520	23	25	when	when	SCONJ
dti-2520	23	26	germs	germ	NOUN
dti-2520	23	27	like	like	ADP
dti-2520	23	28	bacteria	bacteria	NOUN
dti-2520	23	29	,	,	PUNCT
dti-2520	23	30	fungi	fungus	NOUN
dti-2520	23	31	,	,	PUNCT
dti-2520	23	32	viruses	virus	NOUN
dti-2520	23	33	,	,	PUNCT
dti-2520	23	34	and	and	CCONJ
dti-2520	23	35	parasites	parasite	NOUN
dti-2520	23	36	develop	develop	VERB
dti-2520	23	37	the	the	DET
dti-2520	23	38	ability	ability	NOUN
dti-2520	23	39	to	to	PART
dti-2520	23	40	defeat	defeat	VERB
dti-2520	23	41	the	the	DET
dti-2520	23	42	drugs	drug	NOUN
dti-2520	23	43	designed	design	VERB
dti-2520	23	44	to	to	PART
dti-2520	23	45	kill	kill	VERB
dti-2520	23	46	them	they	PRON
dti-2520	23	47	(	(	PUNCT
dti-2520	23	48	1	1	NUM
dti-2520	23	49	)	)	PUNCT
dti-2520	23	50	.	.	PUNCT
dti-2520	24	1	microbes	microbe	NOUN
dti-2520	24	2	change	change	VERB
dti-2520	24	3	over	over	ADP
dti-2520	24	4	time	time	NOUN
dti-2520	24	5	and	and	CCONJ
dti-2520	24	6	no	no	ADV
dti-2520	24	7	longer	long	ADV
dti-2520	24	8	respond	respond	VERB
dti-2520	24	9	to	to	ADP
dti-2520	24	10	antibiotics	antibiotic	NOUN
dti-2520	24	11	and	and	CCONJ
dti-2520	24	12	other	other	ADJ
dti-2520	24	13	antimicrobial	antimicrobial	ADJ
dti-2520	24	14	drugs	drug	NOUN
dti-2520	24	15	,	,	PUNCT
dti-2520	24	16	making	make	VERB
dti-2520	24	17	infections	infection	NOUN
dti-2520	24	18	harder	hard	ADV
dti-2520	24	19	to	to	PART
dti-2520	24	20	treat	treat	VERB
dti-2520	24	21	and	and	CCONJ
dti-2520	24	22	increasing	increase	VERB
dti-2520	24	23	the	the	DET
dti-2520	24	24	risk	risk	NOUN
dti-2520	24	25	of	of	ADP
dti-2520	24	26	disease	disease	NOUN
dti-2520	24	27	spread	spread	VERB
dti-2520	24	28	,	,	PUNCT
dti-2520	24	29	severe	severe	ADJ
dti-2520	24	30	focus	focus	NOUN
dti-2520	24	31	on	on	ADP
dti-2520	24	32	antimicrobial	antimicrobial	ADJ
dti-2520	24	33	resistance	resistance	NOUN
dti-2520	24	34	(	(	PUNCT
dti-2520	24	35	amr	amr	NOUN
dti-2520	24	36	)	)	PUNCT
dti-2520	24	37	https://creativecommons.org/licenses/by-nc/4.0/legalcode	https://creativecommons.org/licenses/by-nc/4.0/legalcode	NUM
dti-2520	24	38	https://doi.org/10.33393/dti.2022.2520	https://doi.org/10.33393/dti.2022.2520	X
dti-2520	24	39	mailto:dablugupta10@gmail.com	mailto:dablugupta10@gmail.com	NOUN
dti-2520	24	40	gut	gut	NOUN
dti-2520	24	41	microbiota	microbiota	NOUN
dti-2520	24	42	and	and	CCONJ
dti-2520	24	43	sepsis82	sepsis82	NOUN
dti-2520	25	1	©	©	ADP
dti-2520	25	2	2022	2022	NUM
dti-2520	26	1	the	the	DET
dti-2520	26	2	authors	author	NOUN
dti-2520	26	3	.	.	PUNCT
dti-2520	27	1	drug	drug	NOUN
dti-2520	27	2	target	target	NOUN
dti-2520	27	3	insights	insight	NOUN
dti-2520	27	4	issn	issn	VERB
dti-2520	27	5	1177	1177	NUM
dti-2520	27	6	-	-	SYM
dti-2520	27	7	3928	3928	NUM
dti-2520	27	8	www.aboutscience.eu/dti	www.aboutscience.eu/dti	NOUN
dti-2520	27	9	groups	group	NOUN
dti-2520	27	10	anticipated	anticipate	VERB
dti-2520	27	11	that	that	SCONJ
dti-2520	27	12	amr	amr	PROPN
dti-2520	27	13	is	be	AUX
dti-2520	27	14	a	a	DET
dti-2520	27	15	global	global	ADJ
dti-2520	27	16	issue	issue	NOUN
dti-2520	27	17	that	that	PRON
dti-2520	27	18	requires	require	VERB
dti-2520	27	19	a	a	DET
dti-2520	27	20	coordinated	coordinated	ADJ
dti-2520	27	21	action	action	NOUN
dti-2520	27	22	plan	plan	NOUN
dti-2520	27	23	to	to	PART
dti-2520	27	24	address	address	VERB
dti-2520	27	25	.	.	PUNCT
dti-2520	28	1	the	the	DET
dti-2520	28	2	way	way	NOUN
dti-2520	28	3	amr	amr	PROPN
dti-2520	28	4	infections	infection	NOUN
dti-2520	28	5	are	be	AUX
dti-2520	28	6	spreading	spread	VERB
dti-2520	28	7	could	could	AUX
dti-2520	28	8	make	make	VERB
dti-2520	28	9	many	many	ADJ
dti-2520	28	10	bacterial	bacterial	ADJ
dti-2520	28	11	pathogens	pathogen	NOUN
dti-2520	28	12	resistant	resistant	ADJ
dti-2520	28	13	to	to	ADP
dti-2520	28	14	emerging	emerge	VERB
dti-2520	28	15	antibiotics	antibiotic	NOUN
dti-2520	28	16	and	and	CCONJ
dti-2520	28	17	more	more	ADV
dti-2520	28	18	lethal	lethal	ADJ
dti-2520	28	19	in	in	ADP
dti-2520	28	20	the	the	DET
dti-2520	28	21	future	future	NOUN
dti-2520	28	22	than	than	SCONJ
dti-2520	28	23	they	they	PRON
dti-2520	28	24	are	be	AUX
dti-2520	28	25	today	today	NOUN
dti-2520	28	26	(	(	PUNCT
dti-2520	28	27	9	9	NUM
dti-2520	28	28	)	)	PUNCT
dti-2520	28	29	.	.	PUNCT
dti-2520	29	1	india	india	PROPN
dti-2520	29	2	is	be	AUX
dti-2520	29	3	considered	consider	VERB
dti-2520	29	4	the	the	DET
dti-2520	29	5	amr	amr	ADJ
dti-2520	29	6	capital	capital	NOUN
dti-2520	29	7	of	of	ADP
dti-2520	29	8	the	the	DET
dti-2520	29	9	world	world	NOUN
dti-2520	29	10	.	.	PUNCT
dti-2520	30	1	india	india	PROPN
dti-2520	30	2	has	have	VERB
dti-2520	30	3	one	one	NUM
dti-2520	30	4	of	of	ADP
dti-2520	30	5	the	the	DET
dti-2520	30	6	largest	large	ADJ
dti-2520	30	7	numbers	number	NOUN
dti-2520	30	8	of	of	ADP
dti-2520	30	9	antibiotic	antibiotic	ADJ
dti-2520	30	10	-	-	PUNCT
dti-2520	30	11	resistant	resistant	ADJ
dti-2520	30	12	pathogens	pathogen	NOUN
dti-2520	30	13	worldwide	worldwide	ADV
dti-2520	30	14	(	(	PUNCT
dti-2520	30	15	10	10	NUM
dti-2520	30	16	)	)	PUNCT
dti-2520	30	17	.	.	PUNCT
dti-2520	31	1	the	the	DET
dti-2520	31	2	highest	high	ADJ
dti-2520	31	3	burden	burden	NOUN
dti-2520	31	4	of	of	ADP
dti-2520	31	5	multidrug	multidrug	NOUN
dti-2520	31	6	-	-	PUNCT
dti-2520	31	7	resistant	resistant	ADJ
dti-2520	31	8	tuberculosis	tuberculosis	NOUN
dti-2520	31	9	cases	case	NOUN
dti-2520	31	10	has	have	AUX
dti-2520	31	11	been	be	AUX
dti-2520	31	12	reported	report	VERB
dti-2520	31	13	in	in	ADP
dti-2520	31	14	different	different	ADJ
dti-2520	31	15	parts	part	NOUN
dti-2520	31	16	of	of	ADP
dti-2520	31	17	india	india	PROPN
dti-2520	31	18	,	,	PUNCT
dti-2520	31	19	as	as	ADP
dti-2520	31	20	alarmingly	alarmingly	ADV
dti-2520	31	21	high	high	ADJ
dti-2520	31	22	-	-	PUNCT
dti-2520	31	23	resistance	resistance	NOUN
dti-2520	31	24	bacterial	bacterial	ADJ
dti-2520	31	25	cases	case	NOUN
dti-2520	31	26	(	(	PUNCT
dti-2520	31	27	11	11	NUM
dti-2520	31	28	)	)	PUNCT
dti-2520	31	29	.	.	PUNCT
dti-2520	32	1	india	india	PROPN
dti-2520	32	2	is	be	AUX
dti-2520	32	3	one	one	NUM
dti-2520	32	4	of	of	ADP
dti-2520	32	5	the	the	DET
dti-2520	32	6	largest	large	ADJ
dti-2520	32	7	consumers	consumer	NOUN
dti-2520	32	8	of	of	ADP
dti-2520	32	9	antibiotics	antibiotic	NOUN
dti-2520	32	10	worldwide	worldwide	ADV
dti-2520	32	11	and	and	CCONJ
dti-2520	32	12	consumption	consumption	NOUN
dti-2520	32	13	and	and	CCONJ
dti-2520	32	14	sales	sale	NOUN
dti-2520	32	15	of	of	ADP
dti-2520	32	16	antibiotics	antibiotic	NOUN
dti-2520	32	17	continue	continue	VERB
dti-2520	32	18	to	to	PART
dti-2520	32	19	rise	rise	VERB
dti-2520	32	20	rapidly	rapidly	ADV
dti-2520	32	21	.	.	PUNCT
dti-2520	33	1	despite	despite	SCONJ
dti-2520	33	2	the	the	DET
dti-2520	33	3	decline	decline	NOUN
dti-2520	33	4	in	in	ADP
dti-2520	33	5	the	the	DET
dti-2520	33	6	number	number	NOUN
dti-2520	33	7	of	of	ADP
dti-2520	33	8	cases	case	NOUN
dti-2520	33	9	of	of	ADP
dti-2520	33	10	communicable	communicable	NOUN
dti-2520	33	11	diseases	disease	NOUN
dti-2520	33	12	,	,	PUNCT
dti-2520	33	13	the	the	DET
dti-2520	33	14	consumption	consumption	NOUN
dti-2520	33	15	of	of	ADP
dti-2520	33	16	antibiotics	antibiotic	NOUN
dti-2520	33	17	continues	continue	VERB
dti-2520	33	18	to	to	PART
dti-2520	33	19	increase	increase	VERB
dti-2520	33	20	(	(	PUNCT
dti-2520	33	21	12	12	NUM
dti-2520	33	22	)	)	PUNCT
dti-2520	33	23	.	.	PUNCT
dti-2520	34	1	on	on	ADP
dti-2520	34	2	the	the	DET
dti-2520	34	3	one	one	NUM
dti-2520	34	4	hand	hand	NOUN
dti-2520	34	5	,	,	PUNCT
dti-2520	34	6	emerging	emerge	VERB
dti-2520	34	7	new	new	ADJ
dti-2520	34	8	multidrug	multidrug	NOUN
dti-2520	34	9	-	-	PUNCT
dti-2520	34	10	resistant	resistant	ADJ
dti-2520	34	11	(	(	PUNCT
dti-2520	34	12	mdr	mdr	NOUN
dti-2520	34	13	)	)	PUNCT
dti-2520	34	14	organisms	organism	NOUN
dti-2520	34	15	pose	pose	VERB
dti-2520	34	16	newer	new	ADJ
dti-2520	34	17	diagnostic	diagnostic	ADJ
dti-2520	34	18	and	and	CCONJ
dti-2520	34	19	therapeutic	therapeutic	ADJ
dti-2520	34	20	challenges	challenge	NOUN
dti-2520	34	21	in	in	ADP
dti-2520	34	22	front	front	NOUN
dti-2520	34	23	of	of	ADP
dti-2520	34	24	policymakers	policymaker	NOUN
dti-2520	34	25	and	and	CCONJ
dti-2520	34	26	health	health	NOUN
dti-2520	34	27	care	care	NOUN
dti-2520	34	28	workers	worker	NOUN
dti-2520	34	29	,	,	PUNCT
dti-2520	34	30	while	while	SCONJ
dti-2520	34	31	on	on	ADP
dti-2520	34	32	the	the	DET
dti-2520	34	33	other	other	ADJ
dti-2520	34	34	hand	hand	NOUN
dti-2520	34	35	india	india	PROPN
dti-2520	34	36	is	be	AUX
dti-2520	34	37	still	still	ADV
dti-2520	34	38	striving	strive	VERB
dti-2520	34	39	to	to	AUX
dti-2520	34	40	battle	battle	VERB
dti-2520	34	41	old	old	ADJ
dti-2520	34	42	enemies	enemy	NOUN
dti-2520	34	43	such	such	ADJ
dti-2520	34	44	as	as	ADP
dti-2520	34	45	malaria	malaria	NOUN
dti-2520	34	46	,	,	PUNCT
dti-2520	34	47	cholera	cholera	NOUN
dti-2520	34	48	,	,	PUNCT
dti-2520	34	49	and	and	CCONJ
dti-2520	34	50	tuberculosis	tuberculosis	NOUN
dti-2520	34	51	(	(	PUNCT
dti-2520	34	52	13	13	NUM
dti-2520	34	53	)	)	PUNCT
dti-2520	34	54	.	.	PUNCT
dti-2520	35	1	infectious	infectious	ADJ
dti-2520	35	2	disease	disease	NOUN
dti-2520	35	3	remains	remain	VERB
dti-2520	35	4	a	a	DET
dti-2520	35	5	leading	lead	VERB
dti-2520	35	6	cause	cause	NOUN
dti-2520	35	7	of	of	ADP
dti-2520	35	8	mortality	mortality	NOUN
dti-2520	35	9	in	in	ADP
dti-2520	35	10	india	india	PROPN
dti-2520	35	11	.	.	PUNCT
dti-2520	36	1	about	about	ADV
dti-2520	36	2	50,000	50,000	NUM
dti-2520	36	3	newborns	newborn	NOUN
dti-2520	36	4	lose	lose	VERB
dti-2520	36	5	the	the	DET
dti-2520	36	6	battle	battle	NOUN
dti-2520	36	7	to	to	ADP
dti-2520	36	8	sepsis	sepsis	NOUN
dti-2520	36	9	annually	annually	ADV
dti-2520	36	10	due	due	ADP
dti-2520	36	11	to	to	ADP
dti-2520	36	12	pathogens	pathogen	NOUN
dti-2520	36	13	resistant	resistant	ADJ
dti-2520	36	14	to	to	ADP
dti-2520	36	15	first	first	ADJ
dti-2520	36	16	-	-	PUNCT
dti-2520	36	17	line	line	NOUN
dti-2520	36	18	antibiotics	antibiotic	NOUN
dti-2520	36	19	(	(	PUNCT
dti-2520	36	20	14	14	NUM
dti-2520	36	21	)	)	PUNCT
dti-2520	36	22	.	.	PUNCT
dti-2520	37	1	two	two	NUM
dti-2520	37	2	million	million	NUM
dti-2520	37	3	deaths	death	NOUN
dti-2520	37	4	are	be	AUX
dti-2520	37	5	anticipated	anticipate	VERB
dti-2520	37	6	in	in	ADP
dti-2520	37	7	india	india	PROPN
dti-2520	37	8	due	due	ADP
dti-2520	37	9	to	to	ADP
dti-2520	37	10	amr	amr	NOUN
dti-2520	37	11	by	by	ADP
dti-2520	37	12	the	the	DET
dti-2520	37	13	year	year	NOUN
dti-2520	37	14	2050	2050	NUM
dti-2520	37	15	(	(	PUNCT
dti-2520	37	16	13	13	NUM
dti-2520	37	17	)	)	PUNCT
dti-2520	37	18	.	.	PUNCT
dti-2520	38	1	there	there	PRON
dti-2520	38	2	are	be	VERB
dti-2520	38	3	several	several	ADJ
dti-2520	38	4	factors	factor	NOUN
dti-2520	38	5	such	such	ADJ
dti-2520	38	6	as	as	ADP
dti-2520	38	7	illiteracy	illiteracy	NOUN
dti-2520	38	8	,	,	PUNCT
dti-2520	38	9	congestion	congestion	NOUN
dti-2520	38	10	,	,	PUNCT
dti-2520	38	11	poverty	poverty	NOUN
dti-2520	38	12	,	,	PUNCT
dti-2520	38	13	malnutrition	malnutrition	NOUN
dti-2520	38	14	,	,	PUNCT
dti-2520	38	15	and	and	CCONJ
dti-2520	38	16	excessive	excessive	ADJ
dti-2520	38	17	antibiotic	antibiotic	ADJ
dti-2520	38	18	use	use	NOUN
dti-2520	38	19	that	that	PRON
dti-2520	38	20	contribute	contribute	VERB
dti-2520	38	21	amr	amr	ADJ
dti-2520	38	22	situation	situation	NOUN
dti-2520	38	23	being	be	AUX
dti-2520	38	24	worse	bad	ADJ
dti-2520	38	25	in	in	ADP
dti-2520	38	26	india	india	PROPN
dti-2520	38	27	.	.	PUNCT
dti-2520	39	1	the	the	DET
dti-2520	39	2	lack	lack	NOUN
dti-2520	39	3	of	of	ADP
dti-2520	39	4	awareness	awareness	NOUN
dti-2520	39	5	about	about	ADP
dti-2520	39	6	the	the	DET
dti-2520	39	7	pathogenesis	pathogenesis	NOUN
dti-2520	39	8	of	of	ADP
dti-2520	39	9	infectious	infectious	ADJ
dti-2520	39	10	diseases	disease	NOUN
dti-2520	39	11	and	and	CCONJ
dti-2520	39	12	their	their	PRON
dti-2520	39	13	spread	spread	NOUN
dti-2520	39	14	among	among	ADP
dti-2520	39	15	the	the	DET
dti-2520	39	16	public	public	NOUN
dti-2520	39	17	and	and	CCONJ
dti-2520	39	18	inaccessibility	inaccessibility	NOUN
dti-2520	39	19	to	to	PART
dti-2520	39	20	healthcare	healthcare	PROPN
dti-2520	39	21	further	far	ADV
dti-2520	39	22	compound	compound	VERB
dti-2520	39	23	the	the	DET
dti-2520	39	24	situation	situation	NOUN
dti-2520	39	25	.	.	PUNCT
dti-2520	40	1	easy	easy	ADJ
dti-2520	40	2	availability	availability	NOUN
dti-2520	40	3	of	of	ADP
dti-2520	40	4	over	over	ADP
dti-2520	40	5	-	-	PUNCT
dti-2520	40	6	the	the	DET
dti-2520	40	7	-	-	PUNCT
dti-2520	40	8	counter	counter	NOUN
dti-2520	40	9	(	(	PUNCT
dti-2520	40	10	otc	otc	ADJ
dti-2520	40	11	)	)	PUNCT
dti-2520	40	12	antimicrobial	antimicrobial	ADJ
dti-2520	40	13	drugs	drug	NOUN
dti-2520	40	14	and	and	CCONJ
dti-2520	40	15	self	self	NOUN
dti-2520	40	16	-	-	PUNCT
dti-2520	40	17	prescription	prescription	NOUN
dti-2520	40	18	of	of	ADP
dti-2520	40	19	these	these	DET
dti-2520	40	20	drugs	drug	NOUN
dti-2520	40	21	without	without	ADP
dti-2520	40	22	any	any	DET
dti-2520	40	23	professional	professional	ADJ
dti-2520	40	24	knowledge	knowledge	NOUN
dti-2520	40	25	regarding	regard	VERB
dti-2520	40	26	the	the	DET
dti-2520	40	27	dose	dose	NOUN
dti-2520	40	28	and	and	CCONJ
dti-2520	40	29	duration	duration	NOUN
dti-2520	40	30	of	of	ADP
dti-2520	40	31	treatment	treatment	NOUN
dti-2520	40	32	significantly	significantly	ADV
dti-2520	40	33	contribute	contribute	VERB
dti-2520	40	34	to	to	ADP
dti-2520	40	35	amr	amr	PROPN
dti-2520	40	36	.	.	PUNCT
dti-2520	41	1	the	the	DET
dti-2520	41	2	lack	lack	NOUN
dti-2520	41	3	of	of	ADP
dti-2520	41	4	tertiary	tertiary	ADJ
dti-2520	41	5	care	care	NOUN
dti-2520	41	6	hospital	hospital	NOUN
dti-2520	41	7	facilities	facility	NOUN
dti-2520	41	8	to	to	PART
dti-2520	41	9	diagnose	diagnose	VERB
dti-2520	41	10	patients	patient	NOUN
dti-2520	41	11	with	with	ADP
dti-2520	41	12	mdr	mdr	PROPN
dti-2520	41	13	,	,	PUNCT
dti-2520	41	14	a	a	DET
dti-2520	41	15	significant	significant	ADJ
dti-2520	41	16	load	load	NOUN
dti-2520	41	17	of	of	ADP
dti-2520	41	18	resistant	resistant	ADJ
dti-2520	41	19	infections	infection	NOUN
dti-2520	41	20	,	,	PUNCT
dti-2520	41	21	and	and	CCONJ
dti-2520	41	22	unregulated	unregulated	ADJ
dti-2520	41	23	sales	sale	NOUN
dti-2520	41	24	of	of	ADP
dti-2520	41	25	antibiotics	antibiotic	NOUN
dti-2520	41	26	have	have	AUX
dti-2520	41	27	contributed	contribute	VERB
dti-2520	41	28	to	to	ADP
dti-2520	41	29	a	a	DET
dti-2520	41	30	speedy	speedy	ADJ
dti-2520	41	31	rise	rise	NOUN
dti-2520	41	32	in	in	ADP
dti-2520	41	33	resistant	resistant	ADJ
dti-2520	41	34	infections	infection	NOUN
dti-2520	41	35	in	in	ADP
dti-2520	41	36	india	india	PROPN
dti-2520	41	37	.	.	PUNCT
dti-2520	42	1	this	this	PRON
dti-2520	42	2	has	have	VERB
dti-2520	42	3	an	an	DET
dti-2520	42	4	enormous	enormous	ADJ
dti-2520	42	5	socioeconomic	socioeconomic	ADJ
dti-2520	42	6	impact	impact	NOUN
dti-2520	42	7	due	due	ADP
dti-2520	42	8	to	to	ADP
dti-2520	42	9	a	a	DET
dti-2520	42	10	large	large	ADJ
dti-2520	42	11	number	number	NOUN
dti-2520	42	12	of	of	ADP
dti-2520	42	13	deaths	death	NOUN
dti-2520	42	14	and	and	CCONJ
dti-2520	42	15	increased	increase	VERB
dti-2520	42	16	costs	cost	NOUN
dti-2520	42	17	due	due	ADJ
dti-2520	42	18	to	to	ADP
dti-2520	42	19	protracted	protract	VERB
dti-2520	42	20	stay	stay	NOUN
dti-2520	42	21	in	in	ADP
dti-2520	42	22	the	the	DET
dti-2520	42	23	hospital	hospital	NOUN
dti-2520	42	24	.	.	PUNCT
dti-2520	43	1	despite	despite	SCONJ
dti-2520	43	2	the	the	DET
dti-2520	43	3	high	high	ADJ
dti-2520	43	4	burden	burden	NOUN
dti-2520	43	5	of	of	ADP
dti-2520	43	6	amr	amr	ADJ
dti-2520	43	7	cases	case	NOUN
dti-2520	43	8	and	and	CCONJ
dti-2520	43	9	the	the	DET
dti-2520	43	10	continuous	continuous	ADJ
dti-2520	43	11	rise	rise	NOUN
dti-2520	43	12	in	in	ADP
dti-2520	43	13	resistance	resistance	NOUN
dti-2520	43	14	cases	case	NOUN
dti-2520	43	15	,	,	PUNCT
dti-2520	43	16	india	india	PROPN
dti-2520	43	17	spends	spend	VERB
dti-2520	43	18	only	only	ADV
dti-2520	43	19	4.7	4.7	NUM
dti-2520	43	20	%	%	NOUN
dti-2520	43	21	of	of	ADP
dti-2520	43	22	its	its	PRON
dti-2520	43	23	total	total	ADJ
dti-2520	43	24	gross	gross	ADJ
dti-2520	43	25	domestic	domestic	ADJ
dti-2520	43	26	product	product	NOUN
dti-2520	43	27	(	(	PUNCT
dti-2520	43	28	gdp	gdp	NOUN
dti-2520	43	29	)	)	PUNCT
dti-2520	43	30	on	on	ADP
dti-2520	43	31	health	health	NOUN
dti-2520	43	32	.	.	PUNCT
dti-2520	44	1	however	however	ADV
dti-2520	44	2	,	,	PUNCT
dti-2520	44	3	the	the	DET
dti-2520	44	4	government	government	NOUN
dti-2520	44	5	shared	share	VERB
dti-2520	44	6	only	only	ADV
dti-2520	44	7	one	one	NUM
dti-2520	44	8	-	-	PUNCT
dti-2520	44	9	fourth	fourth	NOUN
dti-2520	44	10	(	(	PUNCT
dti-2520	44	11	1.15	1.15	NUM
dti-2520	44	12	%	%	NOUN
dti-2520	44	13	)	)	PUNCT
dti-2520	44	14	of	of	ADP
dti-2520	44	15	its	its	PRON
dti-2520	44	16	gdp	gdp	NOUN
dti-2520	44	17	,	,	PUNCT
dti-2520	44	18	making	make	VERB
dti-2520	44	19	the	the	DET
dti-2520	44	20	task	task	NOUN
dti-2520	44	21	massive	massive	ADJ
dti-2520	44	22	(	(	PUNCT
dti-2520	44	23	15	15	NUM
dti-2520	44	24	)	)	PUNCT
dti-2520	44	25	.	.	PUNCT
dti-2520	45	1	the	the	DET
dti-2520	45	2	contribution	contribution	NOUN
dti-2520	45	3	of	of	ADP
dti-2520	45	4	the	the	DET
dti-2520	45	5	government	government	NOUN
dti-2520	45	6	of	of	ADP
dti-2520	45	7	india	india	PROPN
dti-2520	45	8	to	to	ADP
dti-2520	45	9	health	health	NOUN
dti-2520	45	10	is	be	AUX
dti-2520	45	11	very	very	ADV
dti-2520	45	12	poor	poor	ADJ
dti-2520	45	13	(	(	PUNCT
dti-2520	45	14	16	16	NUM
dti-2520	45	15	)	)	PUNCT
dti-2520	45	16	.	.	PUNCT
dti-2520	46	1	in	in	ADP
dti-2520	46	2	2017	2017	NUM
dti-2520	46	3	the	the	DET
dti-2520	46	4	government	government	NOUN
dti-2520	46	5	of	of	ADP
dti-2520	46	6	india	india	PROPN
dti-2520	46	7	adopted	adopt	VERB
dti-2520	46	8	a	a	DET
dti-2520	46	9	national	national	ADJ
dti-2520	46	10	action	action	NOUN
dti-2520	46	11	plan	plan	NOUN
dti-2520	46	12	(	(	PUNCT
dti-2520	46	13	nap	nap	NOUN
dti-2520	46	14	)	)	PUNCT
dti-2520	46	15	on	on	ADP
dti-2520	46	16	amr	amr	PROPN
dti-2520	46	17	.	.	PUNCT
dti-2520	47	1	the	the	DET
dti-2520	47	2	gut	gut	NOUN
dti-2520	47	3	microbiota	microbiota	NOUN
dti-2520	47	4	is	be	AUX
dti-2520	47	5	essentially	essentially	ADV
dti-2520	47	6	required	require	VERB
dti-2520	47	7	to	to	PART
dti-2520	47	8	maintain	maintain	VERB
dti-2520	47	9	gut	gut	NOUN
dti-2520	47	10	homeostasis	homeostasis	NOUN
dti-2520	47	11	by	by	ADP
dti-2520	47	12	mutually	mutually	ADV
dti-2520	47	13	interacting	interact	VERB
dti-2520	47	14	with	with	ADP
dti-2520	47	15	intestinal	intestinal	ADJ
dti-2520	47	16	epithelial	epithelial	ADJ
dti-2520	47	17	cells	cell	NOUN
dti-2520	47	18	and	and	CCONJ
dti-2520	47	19	mucosal	mucosal	ADJ
dti-2520	47	20	immune	immune	ADJ
dti-2520	47	21	cells	cell	NOUN
dti-2520	47	22	(	(	PUNCT
dti-2520	47	23	17	17	NUM
dti-2520	47	24	)	)	PUNCT
dti-2520	47	25	.	.	PUNCT
dti-2520	48	1	during	during	ADP
dti-2520	48	2	prolonged	prolonged	ADJ
dti-2520	48	3	inflammation	inflammation	NOUN
dti-2520	48	4	,	,	PUNCT
dti-2520	48	5	this	this	DET
dti-2520	48	6	interaction	interaction	NOUN
dti-2520	48	7	could	could	AUX
dti-2520	48	8	become	become	VERB
dti-2520	48	9	pathological	pathological	ADJ
dti-2520	48	10	due	due	ADP
dti-2520	48	11	to	to	ADP
dti-2520	48	12	changes	change	NOUN
dti-2520	48	13	in	in	ADP
dti-2520	48	14	the	the	DET
dti-2520	48	15	composition	composition	NOUN
dti-2520	48	16	and	and	CCONJ
dti-2520	48	17	diversity	diversity	NOUN
dti-2520	48	18	of	of	ADP
dti-2520	48	19	gut	gut	NOUN
dti-2520	48	20	microbiota	microbiota	NOUN
dti-2520	48	21	(	(	PUNCT
dti-2520	48	22	18	18	NUM
dti-2520	48	23	)	)	PUNCT
dti-2520	48	24	.	.	PUNCT
dti-2520	49	1	the	the	DET
dti-2520	49	2	loss	loss	NOUN
dti-2520	49	3	of	of	ADP
dti-2520	49	4	diversity	diversity	NOUN
dti-2520	49	5	and	and	CCONJ
dti-2520	49	6	compositions	composition	NOUN
dti-2520	49	7	of	of	ADP
dti-2520	49	8	gut	gut	NOUN
dti-2520	49	9	microbiota	microbiota	NOUN
dti-2520	49	10	may	may	AUX
dti-2520	49	11	lead	lead	VERB
dti-2520	49	12	to	to	ADP
dti-2520	49	13	disruption	disruption	NOUN
dti-2520	49	14	of	of	ADP
dti-2520	49	15	intestinal	intestinal	ADJ
dti-2520	49	16	homeostasis	homeostasis	NOUN
dti-2520	49	17	and	and	CCONJ
dti-2520	49	18	deleterious	deleterious	ADJ
dti-2520	49	19	clinical	clinical	ADJ
dti-2520	49	20	manifestations	manifestation	NOUN
dti-2520	49	21	(	(	PUNCT
dti-2520	49	22	19	19	NUM
dti-2520	49	23	)	)	PUNCT
dti-2520	49	24	.	.	PUNCT
dti-2520	50	1	recent	recent	ADJ
dti-2520	50	2	studies	study	NOUN
dti-2520	50	3	reported	report	VERB
dti-2520	50	4	the	the	DET
dti-2520	50	5	key	key	ADJ
dti-2520	50	6	role	role	NOUN
dti-2520	50	7	of	of	ADP
dti-2520	50	8	microbiota	microbiota	NOUN
dti-2520	50	9	and	and	CCONJ
dti-2520	50	10	their	their	PRON
dti-2520	50	11	metabolites	metabolite	NOUN
dti-2520	50	12	in	in	ADP
dti-2520	50	13	the	the	DET
dti-2520	50	14	development	development	NOUN
dti-2520	50	15	of	of	ADP
dti-2520	50	16	gut	gut	NOUN
dti-2520	50	17	-	-	PUNCT
dti-2520	50	18	derived	derive	VERB
dti-2520	50	19	infection	infection	NOUN
dti-2520	50	20	,	,	PUNCT
dti-2520	50	21	sepsis	sepsis	NOUN
dti-2520	50	22	,	,	PUNCT
dti-2520	50	23	and	and	CCONJ
dti-2520	50	24	multiple	multiple	ADJ
dti-2520	50	25	organ	organ	NOUN
dti-2520	50	26	dysfunctions	dysfunction	NOUN
dti-2520	50	27	in	in	ADP
dti-2520	50	28	sepsis	sepsis	NOUN
dti-2520	50	29	(	(	PUNCT
dti-2520	50	30	20	20	NUM
dti-2520	50	31	)	)	PUNCT
dti-2520	50	32	.	.	PUNCT
dti-2520	51	1	therefore	therefore	ADV
dti-2520	51	2	,	,	PUNCT
dti-2520	51	3	it	it	PRON
dti-2520	51	4	is	be	AUX
dti-2520	51	5	important	important	ADJ
dti-2520	51	6	to	to	PART
dti-2520	51	7	understand	understand	VERB
dti-2520	51	8	the	the	DET
dti-2520	51	9	gut	gut	ADJ
dti-2520	51	10	microbiota	microbiota	NOUN
dti-2520	51	11	composition	composition	NOUN
dti-2520	51	12	,	,	PUNCT
dti-2520	51	13	diversity	diversity	NOUN
dti-2520	51	14	,	,	PUNCT
dti-2520	51	15	and	and	CCONJ
dti-2520	51	16	functions	function	NOUN
dti-2520	51	17	of	of	ADP
dti-2520	51	18	their	their	PRON
dti-2520	51	19	metabolites	metabolite	NOUN
dti-2520	51	20	during	during	ADP
dti-2520	51	21	sepsis	sepsis	NOUN
dti-2520	51	22	and	and	CCONJ
dti-2520	51	23	other	other	ADJ
dti-2520	51	24	inflammatory	inflammatory	ADJ
dti-2520	51	25	conditions	condition	NOUN
dti-2520	51	26	.	.	PUNCT
dti-2520	52	1	the	the	DET
dti-2520	52	2	present	present	ADJ
dti-2520	52	3	review	review	NOUN
dti-2520	52	4	article	article	NOUN
dti-2520	52	5	may	may	AUX
dti-2520	52	6	provide	provide	VERB
dti-2520	52	7	a	a	DET
dti-2520	52	8	more	more	ADV
dti-2520	52	9	inclusive	inclusive	ADJ
dti-2520	52	10	understanding	understanding	NOUN
dti-2520	52	11	of	of	ADP
dti-2520	52	12	the	the	DET
dti-2520	52	13	mechanisms	mechanism	NOUN
dti-2520	52	14	of	of	ADP
dti-2520	52	15	gut	gut	NOUN
dti-2520	52	16	-	-	PUNCT
dti-2520	52	17	derived	derive	VERB
dti-2520	52	18	infection	infection	NOUN
dti-2520	52	19	in	in	ADP
dti-2520	52	20	the	the	DET
dti-2520	52	21	pathogenesis	pathogenesis	NOUN
dti-2520	52	22	of	of	ADP
dti-2520	52	23	sepsis	sepsis	NOUN
dti-2520	52	24	and	and	CCONJ
dti-2520	52	25	the	the	DET
dti-2520	52	26	design	design	NOUN
dti-2520	52	27	of	of	ADP
dti-2520	52	28	new	new	ADJ
dti-2520	52	29	treatment	treatment	NOUN
dti-2520	52	30	options	option	NOUN
dti-2520	52	31	.	.	PUNCT
dti-2520	53	1	here	here	ADV
dti-2520	53	2	,	,	PUNCT
dti-2520	53	3	we	we	PRON
dti-2520	53	4	present	present	VERB
dti-2520	53	5	current	current	ADJ
dti-2520	53	6	knowledge	knowledge	NOUN
dti-2520	53	7	and	and	CCONJ
dti-2520	53	8	key	key	ADJ
dti-2520	53	9	concepts	concept	NOUN
dti-2520	53	10	linking	link	VERB
dti-2520	53	11	gut	gut	ADJ
dti-2520	53	12	microbiota	microbiota	NOUN
dti-2520	53	13	to	to	ADP
dti-2520	53	14	the	the	DET
dti-2520	53	15	development	development	NOUN
dti-2520	53	16	and	and	CCONJ
dti-2520	53	17	function	function	NOUN
dti-2520	53	18	of	of	ADP
dti-2520	53	19	the	the	DET
dti-2520	53	20	immune	immune	ADJ
dti-2520	53	21	system	system	NOUN
dti-2520	53	22	.	.	PUNCT
dti-2520	54	1	through	through	ADP
dti-2520	54	2	this	this	DET
dti-2520	54	3	article	article	NOUN
dti-2520	54	4	,	,	PUNCT
dti-2520	54	5	we	we	PRON
dti-2520	54	6	discuss	discuss	VERB
dti-2520	54	7	how	how	SCONJ
dti-2520	54	8	amr	amr	PROPN
dti-2520	54	9	causes	cause	VERB
dti-2520	54	10	the	the	DET
dti-2520	54	11	defective	defective	ADJ
dti-2520	54	12	host	host	NOUN
dti-2520	54	13	immune	immune	ADJ
dti-2520	54	14	system	system	NOUN
dti-2520	54	15	activation	activation	NOUN
dti-2520	54	16	by	by	ADP
dti-2520	54	17	modulating	modulate	VERB
dti-2520	54	18	the	the	DET
dti-2520	54	19	gut	gut	NOUN
dti-2520	54	20	microbiota	microbiota	NOUN
dti-2520	54	21	,	,	PUNCT
dti-2520	54	22	the	the	DET
dti-2520	54	23	current	current	ADJ
dti-2520	54	24	progress	progress	NOUN
dti-2520	54	25	in	in	ADP
dti-2520	54	26	the	the	DET
dti-2520	54	27	field	field	NOUN
dti-2520	54	28	,	,	PUNCT
dti-2520	54	29	and	and	CCONJ
dti-2520	54	30	identify	identify	VERB
dti-2520	54	31	the	the	DET
dti-2520	54	32	need	need	NOUN
dti-2520	54	33	for	for	ADP
dti-2520	54	34	experimental	experimental	ADJ
dti-2520	54	35	studies	study	NOUN
dti-2520	54	36	investigating	investigate	VERB
dti-2520	54	37	the	the	DET
dti-2520	54	38	use	use	NOUN
dti-2520	54	39	of	of	ADP
dti-2520	54	40	these	these	DET
dti-2520	54	41	treatments	treatment	NOUN
dti-2520	54	42	in	in	ADP
dti-2520	54	43	sepsis	sepsis	NOUN
dti-2520	54	44	management	management	NOUN
dti-2520	54	45	.	.	PUNCT
dti-2520	55	1	finally	finally	ADV
dti-2520	55	2	,	,	PUNCT
dti-2520	55	3	we	we	PRON
dti-2520	55	4	highlighted	highlight	VERB
dti-2520	55	5	the	the	DET
dti-2520	55	6	challenges	challenge	NOUN
dti-2520	55	7	and	and	CCONJ
dti-2520	55	8	perspectives	perspective	NOUN
dti-2520	55	9	of	of	ADP
dti-2520	55	10	microbiome	microbiome	NOUN
dti-2520	55	11	-	-	PUNCT
dti-2520	55	12	targeted	target	VERB
dti-2520	55	13	approaches	approach	NOUN
dti-2520	55	14	in	in	ADP
dti-2520	55	15	studying	study	VERB
dti-2520	55	16	disease	disease	NOUN
dti-2520	55	17	pathogenesis	pathogenesis	NOUN
dti-2520	55	18	and	and	CCONJ
dti-2520	55	19	developing	develop	VERB
dti-2520	55	20	new	new	ADJ
dti-2520	55	21	microbiome	microbiome	NOUN
dti-2520	55	22	-	-	PUNCT
dti-2520	55	23	related	relate	VERB
dti-2520	55	24	treatments	treatment	NOUN
dti-2520	55	25	.	.	PUNCT
dti-2520	56	1	gut	gut	VERB
dti-2520	56	2	microbiota	microbiota	NOUN
dti-2520	56	3	in	in	ADP
dti-2520	56	4	health	health	NOUN
dti-2520	56	5	and	and	CCONJ
dti-2520	56	6	disease	disease	NOUN
dti-2520	56	7	the	the	DET
dti-2520	56	8	mammalian	mammalian	ADJ
dti-2520	56	9	gut	gut	NOUN
dti-2520	56	10	contains	contain	VERB
dti-2520	56	11	highly	highly	ADV
dti-2520	56	12	diverse	diverse	ADJ
dti-2520	56	13	and	and	CCONJ
dti-2520	56	14	wide	wide	ADJ
dti-2520	56	15	varieties	variety	NOUN
dti-2520	56	16	of	of	ADP
dti-2520	56	17	the	the	DET
dti-2520	56	18	microbial	microbial	ADJ
dti-2520	56	19	community	community	NOUN
dti-2520	56	20	called	call	VERB
dti-2520	56	21	the	the	DET
dti-2520	56	22	microbiome	microbiome	NOUN
dti-2520	56	23	,	,	PUNCT
dti-2520	56	24	which	which	PRON
dti-2520	56	25	includes	include	VERB
dti-2520	56	26	mostly	mostly	ADV
dti-2520	56	27	bacteria	bacteria	NOUN
dti-2520	56	28	,	,	PUNCT
dti-2520	56	29	viruses	virus	NOUN
dti-2520	56	30	,	,	PUNCT
dti-2520	56	31	fungi	fungus	NOUN
dti-2520	56	32	,	,	PUNCT
dti-2520	56	33	etc	etc	X
dti-2520	56	34	.	.	X
dti-2520	57	1	gut	gut	NOUN
dti-2520	57	2	microbiota	microbiota	NOUN
dti-2520	57	3	includes	include	VERB
dti-2520	57	4	about	about	ADV
dti-2520	57	5	1,000	1,000	NUM
dti-2520	57	6	to	to	ADP
dti-2520	57	7	1,500	1,500	NUM
dti-2520	57	8	bacterial	bacterial	ADJ
dti-2520	57	9	species	specie	NOUN
dti-2520	57	10	(	(	PUNCT
dti-2520	57	11	21	21	NUM
dti-2520	57	12	)	)	PUNCT
dti-2520	57	13	.	.	PUNCT
dti-2520	58	1	gut	gut	NOUN
dti-2520	58	2	microbiota	microbiota	NOUN
dti-2520	58	3	is	be	AUX
dti-2520	58	4	highly	highly	ADV
dti-2520	58	5	dynamic	dynamic	ADJ
dti-2520	58	6	and	and	CCONJ
dti-2520	58	7	varies	vary	VERB
dti-2520	58	8	from	from	ADP
dti-2520	58	9	one	one	NUM
dti-2520	58	10	individual	individual	NOUN
dti-2520	58	11	to	to	ADP
dti-2520	58	12	another	another	DET
dti-2520	58	13	individual	individual	NOUN
dti-2520	58	14	.	.	PUNCT
dti-2520	59	1	the	the	DET
dti-2520	59	2	diversity	diversity	NOUN
dti-2520	59	3	of	of	ADP
dti-2520	59	4	gut	gut	NOUN
dti-2520	59	5	microbiota	microbiota	NOUN
dti-2520	59	6	can	can	AUX
dti-2520	59	7	be	be	AUX
dti-2520	59	8	imagined	imagine	VERB
dti-2520	59	9	from	from	ADP
dti-2520	59	10	the	the	DET
dti-2520	59	11	data	datum	NOUN
dti-2520	59	12	obtained	obtain	VERB
dti-2520	59	13	from	from	ADP
dti-2520	59	14	an	an	DET
dti-2520	59	15	individual	individual	NOUN
dti-2520	59	16	that	that	PRON
dti-2520	59	17	contains	contain	VERB
dti-2520	59	18	only	only	ADV
dti-2520	59	19	about	about	ADV
dti-2520	59	20	160	160	NUM
dti-2520	59	21	bacterial	bacterial	ADJ
dti-2520	59	22	species	specie	NOUN
dti-2520	59	23	(	(	PUNCT
dti-2520	59	24	22	22	NUM
dti-2520	59	25	)	)	PUNCT
dti-2520	59	26	.	.	PUNCT
dti-2520	60	1	it	it	PRON
dti-2520	60	2	indicates	indicate	VERB
dti-2520	60	3	that	that	SCONJ
dti-2520	60	4	the	the	DET
dti-2520	60	5	composition	composition	NOUN
dti-2520	60	6	of	of	ADP
dti-2520	60	7	gut	gut	NOUN
dti-2520	60	8	microbiota	microbiota	NOUN
dti-2520	60	9	is	be	AUX
dti-2520	60	10	highly	highly	ADV
dti-2520	60	11	diverse	diverse	ADJ
dti-2520	60	12	among	among	ADP
dti-2520	60	13	individuals	individual	NOUN
dti-2520	60	14	and	and	CCONJ
dti-2520	60	15	depends	depend	VERB
dti-2520	60	16	on	on	ADP
dti-2520	60	17	nutrition	nutrition	NOUN
dti-2520	60	18	,	,	PUNCT
dti-2520	60	19	environmental	environmental	ADJ
dti-2520	60	20	changes	change	NOUN
dti-2520	60	21	,	,	PUNCT
dti-2520	60	22	and	and	CCONJ
dti-2520	60	23	genetic	genetic	ADJ
dti-2520	60	24	inheritance	inheritance	NOUN
dti-2520	60	25	(	(	PUNCT
dti-2520	60	26	21,22	21,22	NOUN
dti-2520	60	27	)	)	PUNCT
dti-2520	60	28	.	.	PUNCT
dti-2520	61	1	nutrition	nutrition	NOUN
dti-2520	61	2	and	and	CCONJ
dti-2520	61	3	environmental	environmental	ADJ
dti-2520	61	4	factors	factor	NOUN
dti-2520	61	5	are	be	AUX
dti-2520	61	6	very	very	ADV
dti-2520	61	7	important	important	ADJ
dti-2520	61	8	in	in	ADP
dti-2520	61	9	determining	determine	VERB
dti-2520	61	10	bacterial	bacterial	ADJ
dti-2520	61	11	richness	richness	NOUN
dti-2520	61	12	and	and	CCONJ
dti-2520	61	13	diversity	diversity	NOUN
dti-2520	61	14	among	among	ADP
dti-2520	61	15	individuals	individual	NOUN
dti-2520	61	16	(	(	PUNCT
dti-2520	61	17	23	23	NUM
dti-2520	61	18	)	)	PUNCT
dti-2520	61	19	.	.	PUNCT
dti-2520	62	1	a	a	DET
dti-2520	62	2	direct	direct	ADJ
dti-2520	62	3	mutual	mutual	ADJ
dti-2520	62	4	association	association	NOUN
dti-2520	62	5	between	between	ADP
dti-2520	62	6	gut	gut	NOUN
dti-2520	62	7	microbiota	microbiota	NOUN
dti-2520	62	8	and	and	CCONJ
dti-2520	62	9	the	the	DET
dti-2520	62	10	host	host	NOUN
dti-2520	62	11	is	be	AUX
dti-2520	62	12	reported	report	VERB
dti-2520	62	13	in	in	ADP
dti-2520	62	14	several	several	ADJ
dti-2520	62	15	studies	study	NOUN
dti-2520	62	16	.	.	PUNCT
dti-2520	63	1	the	the	DET
dti-2520	63	2	gut	gut	NOUN
dti-2520	63	3	provides	provide	VERB
dti-2520	63	4	a	a	DET
dti-2520	63	5	favorable	favorable	ADJ
dti-2520	63	6	condition	condition	NOUN
dti-2520	63	7	for	for	ADP
dti-2520	63	8	the	the	DET
dti-2520	63	9	growth	growth	NOUN
dti-2520	63	10	and	and	CCONJ
dti-2520	63	11	development	development	NOUN
dti-2520	63	12	of	of	ADP
dti-2520	63	13	microbiota	microbiota	NOUN
dti-2520	63	14	,	,	PUNCT
dti-2520	63	15	and	and	CCONJ
dti-2520	63	16	the	the	DET
dti-2520	63	17	gut	gut	NOUN
dti-2520	63	18	microbiota	microbiota	NOUN
dti-2520	63	19	supports	support	VERB
dti-2520	63	20	the	the	DET
dti-2520	63	21	maturation	maturation	NOUN
dti-2520	63	22	of	of	ADP
dti-2520	63	23	the	the	DET
dti-2520	63	24	mucosal	mucosal	ADJ
dti-2520	63	25	immune	immune	ADJ
dti-2520	63	26	system	system	NOUN
dti-2520	63	27	and	and	CCONJ
dti-2520	63	28	metabolic	metabolic	NOUN
dti-2520	63	29	system	system	NOUN
dti-2520	63	30	by	by	ADP
dti-2520	63	31	providing	provide	VERB
dti-2520	63	32	beneficial	beneficial	ADJ
dti-2520	63	33	nutrients	nutrient	NOUN
dti-2520	63	34	such	such	ADJ
dti-2520	63	35	as	as	ADP
dti-2520	63	36	vitamins	vitamin	NOUN
dti-2520	63	37	and	and	CCONJ
dti-2520	63	38	short	short	ADJ
dti-2520	63	39	-	-	PUNCT
dti-2520	63	40	chain	chain	NOUN
dti-2520	63	41	fatty	fatty	NOUN
dti-2520	63	42	acids	acid	NOUN
dti-2520	63	43	(	(	PUNCT
dti-2520	63	44	scfas	scfas	NOUN
dti-2520	63	45	)	)	PUNCT
dti-2520	63	46	(	(	PUNCT
dti-2520	63	47	24	24	NUM
dti-2520	63	48	)	)	PUNCT
dti-2520	63	49	.	.	PUNCT
dti-2520	64	1	therefore	therefore	ADV
dti-2520	64	2	,	,	PUNCT
dti-2520	64	3	understanding	understand	VERB
dti-2520	64	4	the	the	DET
dti-2520	64	5	association	association	NOUN
dti-2520	64	6	between	between	ADP
dti-2520	64	7	the	the	DET
dti-2520	64	8	gut	gut	NOUN
dti-2520	64	9	microbiota	microbiota	NOUN
dti-2520	64	10	and	and	CCONJ
dti-2520	64	11	its	its	PRON
dti-2520	64	12	metabolites	metabolite	NOUN
dti-2520	64	13	with	with	ADP
dti-2520	64	14	the	the	DET
dti-2520	64	15	intestinal	intestinal	ADJ
dti-2520	64	16	immune	immune	ADJ
dti-2520	64	17	system	system	NOUN
dti-2520	64	18	is	be	AUX
dti-2520	64	19	vital	vital	ADJ
dti-2520	64	20	for	for	ADP
dti-2520	64	21	the	the	DET
dti-2520	64	22	development	development	NOUN
dti-2520	64	23	and	and	CCONJ
dti-2520	64	24	maturation	maturation	NOUN
dti-2520	64	25	of	of	ADP
dti-2520	64	26	the	the	DET
dti-2520	64	27	mucosal	mucosal	ADJ
dti-2520	64	28	immune	immune	ADJ
dti-2520	64	29	system	system	NOUN
dti-2520	64	30	.	.	PUNCT
dti-2520	65	1	a	a	DET
dti-2520	65	2	change	change	NOUN
dti-2520	65	3	in	in	ADP
dti-2520	65	4	the	the	DET
dti-2520	65	5	richness	richness	NOUN
dti-2520	65	6	and	and	CCONJ
dti-2520	65	7	diversity	diversity	NOUN
dti-2520	65	8	of	of	ADP
dti-2520	65	9	the	the	DET
dti-2520	65	10	microbiome	microbiome	ADJ
dti-2520	65	11	profile	profile	NOUN
dti-2520	65	12	in	in	ADP
dti-2520	65	13	the	the	DET
dti-2520	65	14	gut	gut	NOUN
dti-2520	65	15	is	be	AUX
dti-2520	65	16	known	know	VERB
dti-2520	65	17	as	as	ADP
dti-2520	65	18	dysbiosis	dysbiosis	NOUN
dti-2520	65	19	.	.	PUNCT
dti-2520	66	1	the	the	DET
dti-2520	66	2	dysbiosis	dysbiosis	NOUN
dti-2520	66	3	of	of	ADP
dti-2520	66	4	gut	gut	NOUN
dti-2520	66	5	microbiota	microbiota	NOUN
dti-2520	66	6	is	be	AUX
dti-2520	66	7	closely	closely	ADV
dti-2520	66	8	linked	link	VERB
dti-2520	66	9	to	to	ADP
dti-2520	66	10	several	several	ADJ
dti-2520	66	11	diseases	disease	NOUN
dti-2520	66	12	,	,	PUNCT
dti-2520	66	13	such	such	ADJ
dti-2520	66	14	as	as	ADP
dti-2520	66	15	type	type	NOUN
dti-2520	66	16	2	2	NUM
dti-2520	66	17	diabetes	diabetes	NOUN
dti-2520	66	18	,	,	PUNCT
dti-2520	66	19	obesity	obesity	NOUN
dti-2520	66	20	,	,	PUNCT
dti-2520	66	21	hypertension	hypertension	NOUN
dti-2520	66	22	,	,	PUNCT
dti-2520	66	23	necrotizing	necrotize	VERB
dti-2520	66	24	enterocolitis	enterocolitis	NOUN
dti-2520	66	25	(	(	PUNCT
dti-2520	66	26	nec	nec	PROPN
dti-2520	66	27	)	)	PUNCT
dti-2520	66	28	,	,	PUNCT
dti-2520	66	29	inflammatory	inflammatory	ADJ
dti-2520	66	30	bowel	bowel	NOUN
dti-2520	66	31	disease	disease	NOUN
dti-2520	66	32	(	(	PUNCT
dti-2520	66	33	ibd	ibd	PROPN
dti-2520	66	34	)	)	PUNCT
dti-2520	66	35	,	,	PUNCT
dti-2520	66	36	etc	etc	X
dti-2520	66	37	.	.	X
dti-2520	67	1	(	(	PUNCT
dti-2520	67	2	18,25	18,25	NUM
dti-2520	67	3	)	)	PUNCT
dti-2520	67	4	.	.	PUNCT
dti-2520	68	1	gut	gut	NOUN
dti-2520	68	2	dysbiosis	dysbiosis	NOUN
dti-2520	68	3	leads	lead	VERB
dti-2520	68	4	to	to	ADP
dti-2520	68	5	the	the	DET
dti-2520	68	6	development	development	NOUN
dti-2520	68	7	of	of	ADP
dti-2520	68	8	gut	gut	NOUN
dti-2520	68	9	barrier	barrier	NOUN
dti-2520	68	10	dysfunction	dysfunction	NOUN
dti-2520	68	11	and	and	CCONJ
dti-2520	68	12	bacterial	bacterial	ADJ
dti-2520	68	13	translocation	translocation	NOUN
dti-2520	68	14	.	.	PUNCT
dti-2520	69	1	it	it	PRON
dti-2520	69	2	impairs	impair	VERB
dti-2520	69	3	the	the	DET
dti-2520	69	4	ability	ability	NOUN
dti-2520	69	5	to	to	PART
dti-2520	69	6	maintain	maintain	VERB
dti-2520	69	7	mucosal	mucosal	ADJ
dti-2520	69	8	membrane	membrane	NOUN
dti-2520	69	9	function	function	NOUN
dti-2520	69	10	and	and	CCONJ
dti-2520	69	11	contributes	contribute	VERB
dti-2520	69	12	to	to	ADP
dti-2520	69	13	systemic	systemic	ADJ
dti-2520	69	14	inflammation	inflammation	NOUN
dti-2520	69	15	(	(	PUNCT
dti-2520	69	16	26	26	NUM
dti-2520	69	17	)	)	PUNCT
dti-2520	69	18	.	.	PUNCT
dti-2520	70	1	when	when	SCONJ
dti-2520	70	2	dysbiosis	dysbiosis	NOUN
dti-2520	70	3	occurs	occur	VERB
dti-2520	70	4	,	,	PUNCT
dti-2520	70	5	bacteria	bacteria	NOUN
dti-2520	70	6	and	and	CCONJ
dti-2520	70	7	bacterial	bacterial	ADJ
dti-2520	70	8	endotoxins	endotoxin	NOUN
dti-2520	70	9	or	or	CCONJ
dti-2520	70	10	toxins	toxin	NOUN
dti-2520	70	11	can	can	AUX
dti-2520	70	12	leak	leak	VERB
dti-2520	70	13	from	from	ADP
dti-2520	70	14	the	the	DET
dti-2520	70	15	gut	gut	NOUN
dti-2520	70	16	,	,	PUNCT
dti-2520	70	17	along	along	ADP
dti-2520	70	18	with	with	ADP
dti-2520	70	19	food	food	NOUN
dti-2520	70	20	particles	particle	NOUN
dti-2520	70	21	.	.	PUNCT
dti-2520	71	1	this	this	DET
dti-2520	71	2	systemic	systemic	ADJ
dti-2520	71	3	translocation	translocation	NOUN
dti-2520	71	4	of	of	ADP
dti-2520	71	5	bacteria	bacteria	NOUN
dti-2520	71	6	and	and	CCONJ
dti-2520	71	7	bacterial	bacterial	ADJ
dti-2520	71	8	products	product	NOUN
dti-2520	71	9	is	be	AUX
dti-2520	71	10	responsible	responsible	ADJ
dti-2520	71	11	for	for	ADP
dti-2520	71	12	other	other	ADJ
dti-2520	71	13	clinical	clinical	ADJ
dti-2520	71	14	manifestations	manifestation	NOUN
dti-2520	71	15	in	in	ADP
dti-2520	71	16	critically	critically	ADV
dti-2520	71	17	ill	ill	ADJ
dti-2520	71	18	patients	patient	NOUN
dti-2520	71	19	(	(	PUNCT
dti-2520	71	20	27	27	NUM
dti-2520	71	21	)	)	PUNCT
dti-2520	71	22	.	.	PUNCT
dti-2520	72	1	the	the	DET
dti-2520	72	2	different	different	ADJ
dti-2520	72	3	bacterial	bacterial	ADJ
dti-2520	72	4	genera	genera	NOUN
dti-2520	72	5	present	present	NOUN
dti-2520	72	6	in	in	ADP
dti-2520	72	7	the	the	DET
dti-2520	72	8	gut	gut	NOUN
dti-2520	72	9	are	be	AUX
dti-2520	72	10	likely	likely	ADJ
dti-2520	72	11	to	to	PART
dti-2520	72	12	affect	affect	VERB
dti-2520	72	13	the	the	DET
dti-2520	72	14	intestinal	intestinal	ADJ
dti-2520	72	15	environment	environment	NOUN
dti-2520	72	16	of	of	ADP
dti-2520	72	17	the	the	DET
dti-2520	72	18	hosts	host	NOUN
dti-2520	72	19	and	and	CCONJ
dti-2520	72	20	alter	alter	VERB
dti-2520	72	21	the	the	DET
dti-2520	72	22	metabolic	metabolic	NOUN
dti-2520	72	23	patterns	pattern	NOUN
dti-2520	72	24	and	and	CCONJ
dti-2520	72	25	influence	influence	VERB
dti-2520	72	26	the	the	DET
dti-2520	72	27	occurrence	occurrence	NOUN
dti-2520	72	28	of	of	ADP
dti-2520	72	29	diseases	disease	NOUN
dti-2520	72	30	.	.	PUNCT
dti-2520	73	1	the	the	DET
dti-2520	73	2	altered	alter	VERB
dti-2520	73	3	gut	gut	NOUN
dti-2520	73	4	microbiota	microbiota	NOUN
dti-2520	73	5	is	be	AUX
dti-2520	73	6	also	also	ADV
dti-2520	73	7	associated	associate	VERB
dti-2520	73	8	with	with	ADP
dti-2520	73	9	metabolic	metabolic	NOUN
dti-2520	73	10	parameters	parameter	NOUN
dti-2520	73	11	,	,	PUNCT
dti-2520	73	12	sex	sex	NOUN
dti-2520	73	13	hormones	hormone	NOUN
dti-2520	73	14	,	,	PUNCT
dti-2520	73	15	and	and	CCONJ
dti-2520	73	16	the	the	DET
dti-2520	73	17	mediators	mediator	NOUN
dti-2520	73	18	of	of	ADP
dti-2520	73	19	the	the	DET
dti-2520	73	20	gut	gut	NOUN
dti-2520	73	21	-	-	PUNCT
dti-2520	73	22	brain	brain	NOUN
dti-2520	73	23	axis	axis	NOUN
dti-2520	73	24	(	(	PUNCT
dti-2520	73	25	22,28	22,28	NUM
dti-2520	73	26	)	)	PUNCT
dti-2520	73	27	.	.	PUNCT
dti-2520	74	1	several	several	ADJ
dti-2520	74	2	studies	study	NOUN
dti-2520	74	3	have	have	AUX
dti-2520	74	4	confirmed	confirm	VERB
dti-2520	74	5	the	the	DET
dti-2520	74	6	role	role	NOUN
dti-2520	74	7	of	of	ADP
dti-2520	74	8	gut	gut	NOUN
dti-2520	74	9	microbiota	microbiota	NOUN
dti-2520	74	10	in	in	ADP
dti-2520	74	11	kalra	kalra	PROPN
dti-2520	74	12	et	et	PROPN
dti-2520	74	13	al	al	PROPN
dti-2520	74	14	drug	drug	PROPN
dti-2520	74	15	target	target	NOUN
dti-2520	74	16	insights	insight	NOUN
dti-2520	74	17	2022	2022	NUM
dti-2520	74	18	;	;	PUNCT
dti-2520	74	19	16	16	NUM
dti-2520	74	20	:	:	SYM
dti-2520	74	21	83	83	NUM
dti-2520	74	22	©	©	ADP
dti-2520	74	23	2022	2022	NUM
dti-2520	74	24	the	the	DET
dti-2520	74	25	authors	author	NOUN
dti-2520	74	26	.	.	PUNCT
dti-2520	75	1	published	publish	VERB
dti-2520	75	2	by	by	ADP
dti-2520	75	3	aboutscience	aboutscience	NOUN
dti-2520	75	4	www.aboutscience.eu	www.aboutscience.eu	NOUN
dti-2520	75	5	sepsis	sepsis	NOUN
dti-2520	75	6	,	,	PUNCT
dti-2520	75	7	but	but	CCONJ
dti-2520	75	8	the	the	DET
dti-2520	75	9	direct	direct	ADJ
dti-2520	75	10	association	association	NOUN
dti-2520	75	11	of	of	ADP
dti-2520	75	12	gut	gut	ADJ
dti-2520	75	13	microbiota	microbiota	NOUN
dti-2520	75	14	diversity	diversity	NOUN
dti-2520	75	15	with	with	ADP
dti-2520	75	16	the	the	DET
dti-2520	75	17	pathogenesis	pathogenesis	NOUN
dti-2520	75	18	of	of	ADP
dti-2520	75	19	disease	disease	NOUN
dti-2520	75	20	and	and	CCONJ
dti-2520	75	21	outcomes	outcome	NOUN
dti-2520	75	22	has	have	AUX
dti-2520	75	23	not	not	PART
dti-2520	75	24	yet	yet	ADV
dti-2520	75	25	been	be	AUX
dti-2520	75	26	fully	fully	ADV
dti-2520	75	27	understood	understand	VERB
dti-2520	75	28	(	(	PUNCT
dti-2520	75	29	20	20	NUM
dti-2520	75	30	)	)	PUNCT
dti-2520	75	31	.	.	PUNCT
dti-2520	76	1	figure	figure	NOUN
dti-2520	76	2	1	1	NUM
dti-2520	76	3	shows	show	VERB
dti-2520	76	4	the	the	DET
dti-2520	76	5	association	association	NOUN
dti-2520	76	6	of	of	ADP
dti-2520	76	7	gut	gut	ADJ
dti-2520	76	8	microbiota	microbiota	NOUN
dti-2520	76	9	dysbiosis	dysbiosis	NOUN
dti-2520	76	10	with	with	ADP
dti-2520	76	11	changed	change	VERB
dti-2520	76	12	metabolites	metabolite	NOUN
dti-2520	76	13	and	and	CCONJ
dti-2520	76	14	immune	immune	ADJ
dti-2520	76	15	system	system	NOUN
dti-2520	76	16	dysregulation	dysregulation	NOUN
dti-2520	76	17	in	in	ADP
dti-2520	76	18	critical	critical	ADJ
dti-2520	76	19	illness	illness	NOUN
dti-2520	76	20	and	and	CCONJ
dti-2520	76	21	disease	disease	NOUN
dti-2520	76	22	.	.	PUNCT
dti-2520	77	1	role	role	NOUN
dti-2520	77	2	of	of	ADP
dti-2520	77	3	gut	gut	NOUN
dti-2520	77	4	microbiota	microbiota	NOUN
dti-2520	77	5	in	in	ADP
dti-2520	77	6	sepsis	sepsis	NOUN
dti-2520	77	7	and	and	CCONJ
dti-2520	77	8	septic	septic	ADJ
dti-2520	77	9	shock	shock	NOUN
dti-2520	77	10	sepsis	sepsis	NOUN
dti-2520	77	11	,	,	PUNCT
dti-2520	77	12	defined	define	VERB
dti-2520	77	13	as	as	ADP
dti-2520	77	14	life	life	NOUN
dti-2520	77	15	-	-	PUNCT
dti-2520	77	16	threatening	threaten	VERB
dti-2520	77	17	organ	organ	NOUN
dti-2520	77	18	dysfunction	dysfunction	NOUN
dti-2520	77	19	caused	cause	VERB
dti-2520	77	20	by	by	ADP
dti-2520	77	21	a	a	DET
dti-2520	77	22	dysregulated	dysregulated	ADJ
dti-2520	77	23	host	host	NOUN
dti-2520	77	24	response	response	NOUN
dti-2520	77	25	to	to	ADP
dti-2520	77	26	infection	infection	NOUN
dti-2520	77	27	,	,	PUNCT
dti-2520	77	28	affects	affect	VERB
dti-2520	77	29	1.7	1.7	NUM
dti-2520	77	30	million	million	NUM
dti-2520	77	31	people	people	NOUN
dti-2520	77	32	annually	annually	ADV
dti-2520	77	33	in	in	ADP
dti-2520	77	34	the	the	DET
dti-2520	77	35	united	united	PROPN
dti-2520	77	36	states	states	PROPN
dti-2520	77	37	(	(	PUNCT
dti-2520	77	38	14	14	NUM
dti-2520	77	39	)	)	PUNCT
dti-2520	77	40	.	.	PUNCT
dti-2520	78	1	about	about	ADP
dti-2520	78	2	20%-30	20%-30	NUM
dti-2520	78	3	%	%	NOUN
dti-2520	78	4	of	of	ADP
dti-2520	78	5	patients	patient	NOUN
dti-2520	78	6	die	die	VERB
dti-2520	78	7	annually	annually	ADV
dti-2520	78	8	across	across	ADP
dti-2520	78	9	the	the	DET
dti-2520	78	10	globe	globe	NOUN
dti-2520	78	11	due	due	ADP
dti-2520	78	12	to	to	ADP
dti-2520	78	13	sepsis	sepsis	NOUN
dti-2520	78	14	(	(	PUNCT
dti-2520	78	15	29	29	NUM
dti-2520	78	16	)	)	PUNCT
dti-2520	78	17	.	.	PUNCT
dti-2520	79	1	it	it	PRON
dti-2520	79	2	is	be	AUX
dti-2520	79	3	recognized	recognize	VERB
dti-2520	79	4	as	as	ADP
dti-2520	79	5	a	a	DET
dti-2520	79	6	global	global	ADJ
dti-2520	79	7	health	health	NOUN
dti-2520	79	8	emergency	emergency	NOUN
dti-2520	79	9	by	by	ADP
dti-2520	79	10	who	who	PRON
dti-2520	79	11	(	(	PUNCT
dti-2520	79	12	30	30	NUM
dti-2520	79	13	)	)	PUNCT
dti-2520	79	14	.	.	PUNCT
dti-2520	80	1	the	the	DET
dti-2520	80	2	overwhelming	overwhelming	ADJ
dti-2520	80	3	inflammatory	inflammatory	ADJ
dti-2520	80	4	response	response	NOUN
dti-2520	80	5	is	be	AUX
dti-2520	80	6	a	a	DET
dti-2520	80	7	hallmark	hallmark	ADJ
dti-2520	80	8	property	property	NOUN
dti-2520	80	9	of	of	ADP
dti-2520	80	10	sepsis	sepsis	NOUN
dti-2520	80	11	.	.	PUNCT
dti-2520	81	1	the	the	DET
dti-2520	81	2	exaggerated	exaggerated	ADJ
dti-2520	81	3	inflammatory	inflammatory	ADJ
dti-2520	81	4	response	response	NOUN
dti-2520	81	5	that	that	PRON
dti-2520	81	6	occurs	occur	VERB
dti-2520	81	7	during	during	ADP
dti-2520	81	8	sepsis	sepsis	NOUN
dti-2520	81	9	may	may	AUX
dti-2520	81	10	lead	lead	VERB
dti-2520	81	11	to	to	ADP
dti-2520	81	12	immune	immune	ADJ
dti-2520	81	13	suppression	suppression	NOUN
dti-2520	81	14	and	and	CCONJ
dti-2520	81	15	dysregulated	dysregulated	ADJ
dti-2520	81	16	immune	immune	ADJ
dti-2520	81	17	response	response	NOUN
dti-2520	81	18	(	(	PUNCT
dti-2520	81	19	31	31	NUM
dti-2520	81	20	)	)	PUNCT
dti-2520	81	21	.	.	PUNCT
dti-2520	82	1	these	these	DET
dti-2520	82	2	dysregulated	dysregulate	VERB
dti-2520	82	3	host	host	NOUN
dti-2520	82	4	immune	immune	ADJ
dti-2520	82	5	responses	response	NOUN
dti-2520	82	6	during	during	ADP
dti-2520	82	7	sepsis	sepsis	NOUN
dti-2520	82	8	may	may	AUX
dti-2520	82	9	lead	lead	VERB
dti-2520	82	10	to	to	ADP
dti-2520	82	11	the	the	DET
dti-2520	82	12	dysfunction	dysfunction	NOUN
dti-2520	82	13	of	of	ADP
dti-2520	82	14	multiple	multiple	ADJ
dti-2520	82	15	organ	organ	NOUN
dti-2520	82	16	systems	system	NOUN
dti-2520	82	17	,	,	PUNCT
dti-2520	82	18	which	which	PRON
dti-2520	82	19	includes	include	VERB
dti-2520	82	20	the	the	DET
dti-2520	82	21	cardiovascular	cardiovascular	ADJ
dti-2520	82	22	,	,	PUNCT
dti-2520	82	23	renal	renal	ADJ
dti-2520	82	24	,	,	PUNCT
dti-2520	82	25	pulmonary	pulmonary	ADJ
dti-2520	82	26	,	,	PUNCT
dti-2520	82	27	hepatic	hepatic	ADJ
dti-2520	82	28	,	,	PUNCT
dti-2520	82	29	and	and	CCONJ
dti-2520	82	30	gastrointestinal	gastrointestinal	ADJ
dti-2520	82	31	systems	system	NOUN
dti-2520	82	32	(	(	PUNCT
dti-2520	82	33	31	31	NUM
dti-2520	82	34	)	)	PUNCT
dti-2520	82	35	.	.	PUNCT
dti-2520	83	1	sepsis	sepsis	NOUN
dti-2520	83	2	-	-	PUNCT
dti-2520	83	3	induced	induce	VERB
dti-2520	83	4	hyperactivation	hyperactivation	NOUN
dti-2520	83	5	of	of	ADP
dti-2520	83	6	immune	immune	ADJ
dti-2520	83	7	cells	cell	NOUN
dti-2520	83	8	and	and	CCONJ
dti-2520	83	9	immune	immune	ADJ
dti-2520	83	10	suppression	suppression	NOUN
dti-2520	83	11	may	may	AUX
dti-2520	83	12	be	be	AUX
dti-2520	83	13	considered	consider	VERB
dti-2520	83	14	the	the	DET
dti-2520	83	15	main	main	ADJ
dti-2520	83	16	contributors	contributor	NOUN
dti-2520	83	17	to	to	ADP
dti-2520	83	18	the	the	DET
dti-2520	83	19	pathophysiology	pathophysiology	NOUN
dti-2520	83	20	of	of	ADP
dti-2520	83	21	sepsis	sepsis	NOUN
dti-2520	83	22	(	(	PUNCT
dti-2520	83	23	32	32	NUM
dti-2520	83	24	)	)	PUNCT
dti-2520	83	25	.	.	PUNCT
dti-2520	84	1	immune	immune	ADJ
dti-2520	84	2	suppression	suppression	NOUN
dti-2520	84	3	often	often	ADV
dti-2520	84	4	increases	increase	VERB
dti-2520	84	5	the	the	DET
dti-2520	84	6	individual	individual	NOUN
dti-2520	84	7	’s	’s	PART
dti-2520	84	8	susceptibility	susceptibility	NOUN
dti-2520	84	9	to	to	ADP
dti-2520	84	10	secondary	secondary	ADJ
dti-2520	84	11	infections	infection	NOUN
dti-2520	84	12	,	,	PUNCT
dti-2520	84	13	further	far	ADV
dti-2520	84	14	increasing	increase	VERB
dti-2520	84	15	the	the	DET
dti-2520	84	16	risk	risk	NOUN
dti-2520	84	17	of	of	ADP
dti-2520	84	18	death	death	NOUN
dti-2520	84	19	(	(	PUNCT
dti-2520	84	20	33	33	NUM
dti-2520	84	21	)	)	PUNCT
dti-2520	84	22	.	.	PUNCT
dti-2520	85	1	the	the	DET
dti-2520	85	2	recent	recent	ADJ
dti-2520	85	3	development	development	NOUN
dti-2520	85	4	of	of	ADP
dti-2520	85	5	molecular	molecular	NOUN
dti-2520	85	6	-	-	PUNCT
dti-2520	85	7	based	base	VERB
dti-2520	85	8	sequencing	sequencing	NOUN
dti-2520	85	9	tools	tool	NOUN
dti-2520	85	10	has	have	AUX
dti-2520	85	11	exposed	expose	VERB
dti-2520	85	12	the	the	DET
dti-2520	85	13	importance	importance	NOUN
dti-2520	85	14	of	of	ADP
dti-2520	85	15	gut	gut	ADJ
dti-2520	85	16	microbiota	microbiota	NOUN
dti-2520	85	17	diversity	diversity	NOUN
dti-2520	85	18	in	in	ADP
dti-2520	85	19	human	human	ADJ
dti-2520	85	20	health	health	NOUN
dti-2520	85	21	and	and	CCONJ
dti-2520	85	22	disease	disease	NOUN
dti-2520	85	23	(	(	PUNCT
dti-2520	85	24	34	34	NUM
dti-2520	85	25	)	)	PUNCT
dti-2520	85	26	.	.	PUNCT
dti-2520	86	1	several	several	ADJ
dti-2520	86	2	studies	study	NOUN
dti-2520	86	3	have	have	AUX
dti-2520	86	4	reported	report	VERB
dti-2520	86	5	gut	gut	NOUN
dti-2520	86	6	dysbiosis	dysbiosis	NOUN
dti-2520	86	7	with	with	ADP
dti-2520	86	8	a	a	DET
dti-2520	86	9	sharp	sharp	ADJ
dti-2520	86	10	decrease	decrease	NOUN
dti-2520	86	11	in	in	ADP
dti-2520	86	12	diversity	diversity	NOUN
dti-2520	86	13	,	,	PUNCT
dti-2520	86	14	overgrowth	overgrowth	NOUN
dti-2520	86	15	of	of	ADP
dti-2520	86	16	pathogenic	pathogenic	ADJ
dti-2520	86	17	bacteria	bacteria	NOUN
dti-2520	86	18	,	,	PUNCT
dti-2520	86	19	and	and	CCONJ
dti-2520	86	20	loss	loss	NOUN
dti-2520	86	21	of	of	ADP
dti-2520	86	22	commensal	commensal	ADJ
dti-2520	86	23	bacteria	bacteria	NOUN
dti-2520	86	24	(	(	PUNCT
dti-2520	86	25	21	21	NUM
dti-2520	86	26	)	)	PUNCT
dti-2520	86	27	.	.	PUNCT
dti-2520	87	1	recent	recent	ADJ
dti-2520	87	2	studies	study	NOUN
dti-2520	87	3	have	have	AUX
dti-2520	87	4	elucidated	elucidate	VERB
dti-2520	87	5	key	key	ADJ
dti-2520	87	6	immune	immune	ADJ
dti-2520	87	7	pathways	pathway	NOUN
dti-2520	87	8	that	that	PRON
dti-2520	87	9	are	be	AUX
dti-2520	87	10	modulated	modulate	VERB
dti-2520	87	11	by	by	ADP
dti-2520	87	12	gut	gut	NOUN
dti-2520	87	13	microbiota	microbiota	NOUN
dti-2520	87	14	and	and	CCONJ
dti-2520	87	15	their	their	PRON
dti-2520	87	16	metabolites	metabolite	NOUN
dti-2520	87	17	(	(	PUNCT
dti-2520	87	18	24	24	NUM
dti-2520	87	19	)	)	PUNCT
dti-2520	87	20	.	.	PUNCT
dti-2520	88	1	the	the	DET
dti-2520	88	2	altered	alter	VERB
dti-2520	88	3	gut	gut	NOUN
dti-2520	88	4	microbiota	microbiota	NOUN
dti-2520	88	5	during	during	ADP
dti-2520	88	6	sepsis	sepsis	NOUN
dti-2520	88	7	may	may	AUX
dti-2520	88	8	influence	influence	VERB
dti-2520	88	9	inflammatory	inflammatory	ADJ
dti-2520	88	10	responses	response	NOUN
dti-2520	88	11	and	and	CCONJ
dti-2520	88	12	increase	increase	VERB
dti-2520	88	13	gut	gut	NOUN
dti-2520	88	14	barrier	barrier	NOUN
dti-2520	88	15	permeability	permeability	NOUN
dti-2520	88	16	,	,	PUNCT
dti-2520	88	17	which	which	PRON
dti-2520	88	18	could	could	AUX
dti-2520	88	19	enable	enable	VERB
dti-2520	88	20	the	the	DET
dti-2520	88	21	translocation	translocation	NOUN
dti-2520	88	22	of	of	ADP
dti-2520	88	23	pathogenic	pathogenic	ADJ
dti-2520	88	24	bacteria	bacteria	NOUN
dti-2520	88	25	to	to	ADP
dti-2520	88	26	the	the	DET
dti-2520	88	27	systemic	systemic	ADJ
dti-2520	88	28	circulation	circulation	NOUN
dti-2520	88	29	and	and	CCONJ
dti-2520	88	30	distant	distant	ADJ
dti-2520	88	31	organs	organ	NOUN
dti-2520	88	32	.	.	PUNCT
dti-2520	89	1	the	the	DET
dti-2520	89	2	increased	increase	VERB
dti-2520	89	3	gut	gut	NOUN
dti-2520	89	4	permeability	permeability	NOUN
dti-2520	89	5	during	during	ADP
dti-2520	89	6	inflammatory	inflammatory	ADJ
dti-2520	89	7	conditions	condition	NOUN
dti-2520	89	8	and	and	CCONJ
dti-2520	89	9	sepsis	sepsis	NOUN
dti-2520	89	10	may	may	AUX
dti-2520	89	11	lead	lead	VERB
dti-2520	89	12	to	to	ADP
dti-2520	89	13	the	the	DET
dti-2520	89	14	translocation	translocation	NOUN
dti-2520	89	15	of	of	ADP
dti-2520	89	16	enteric	enteric	ADJ
dti-2520	89	17	bacteria	bacteria	NOUN
dti-2520	89	18	from	from	ADP
dti-2520	89	19	the	the	DET
dti-2520	89	20	gut	gut	NOUN
dti-2520	89	21	to	to	ADP
dti-2520	89	22	the	the	DET
dti-2520	89	23	systemic	systemic	ADJ
dti-2520	89	24	circulation	circulation	NOUN
dti-2520	89	25	served	serve	VERB
dti-2520	89	26	as	as	ADP
dti-2520	89	27	the	the	DET
dti-2520	89	28	motor	motor	NOUN
dti-2520	89	29	of	of	ADP
dti-2520	89	30	multiple	multiple	ADJ
dti-2520	89	31	organ	organ	NOUN
dti-2520	89	32	dysfunction	dysfunction	NOUN
dti-2520	89	33	syndromes	syndrome	NOUN
dti-2520	89	34	(	(	PUNCT
dti-2520	89	35	mods	mod	NOUN
dti-2520	89	36	)	)	PUNCT
dti-2520	89	37	and	and	CCONJ
dti-2520	89	38	,	,	PUNCT
dti-2520	89	39	subsequently	subsequently	ADV
dti-2520	89	40	,	,	PUNCT
dti-2520	89	41	cause	cause	VERB
dti-2520	89	42	acute	acute	ADJ
dti-2520	89	43	septic	septic	ADJ
dti-2520	89	44	responses	response	NOUN
dti-2520	89	45	(	(	PUNCT
dti-2520	89	46	35	35	NUM
dti-2520	89	47	)	)	PUNCT
dti-2520	89	48	.	.	PUNCT
dti-2520	90	1	the	the	DET
dti-2520	90	2	altered	alter	VERB
dti-2520	90	3	gut	gut	NOUN
dti-2520	90	4	microbiota	microbiota	NOUN
dti-2520	90	5	composition	composition	NOUN
dti-2520	90	6	and	and	CCONJ
dti-2520	90	7	diversity	diversity	NOUN
dti-2520	90	8	during	during	ADP
dti-2520	90	9	inflammatory	inflammatory	ADJ
dti-2520	90	10	conditions	condition	NOUN
dti-2520	90	11	and	and	CCONJ
dti-2520	90	12	subsequently	subsequently	ADV
dti-2520	90	13	enhanced	enhance	VERB
dti-2520	90	14	translocation	translocation	NOUN
dti-2520	90	15	of	of	ADP
dti-2520	90	16	gut	gut	NOUN
dti-2520	90	17	microbiota	microbiota	NOUN
dti-2520	90	18	may	may	AUX
dti-2520	90	19	cause	cause	VERB
dti-2520	90	20	mucosal	mucosal	ADJ
dti-2520	90	21	immune	immune	ADJ
dti-2520	90	22	dysfunction	dysfunction	NOUN
dti-2520	90	23	(	(	PUNCT
dti-2520	90	24	35	35	NUM
dti-2520	90	25	)	)	PUNCT
dti-2520	90	26	.	.	PUNCT
dti-2520	91	1	fig	fig	NOUN
dti-2520	91	2	.	.	PUNCT
dti-2520	92	1	1	1	NUM
dti-2520	92	2	gut	gut	NOUN
dti-2520	92	3	microbiome	microbiome	ADJ
dti-2520	92	4	dysbiosis	dysbiosis	NOUN
dti-2520	92	5	predisposes	predispose	NOUN
dti-2520	92	6	to	to	ADP
dti-2520	92	7	selection	selection	NOUN
dti-2520	92	8	for	for	ADP
dti-2520	92	9	pathogenic	pathogenic	ADJ
dti-2520	92	10	bacteria	bacteria	NOUN
dti-2520	92	11	that	that	PRON
dti-2520	92	12	leads	lead	VERB
dti-2520	92	13	to	to	ADP
dti-2520	92	14	immune	immune	ADJ
dti-2520	92	15	dysregulation	dysregulation	NOUN
dti-2520	92	16	,	,	PUNCT
dti-2520	92	17	and	and	CCONJ
dti-2520	92	18	decreased	decrease	VERB
dti-2520	92	19	production	production	NOUN
dti-2520	92	20	of	of	ADP
dti-2520	92	21	beneficial	beneficial	ADJ
dti-2520	92	22	metabolites	metabolite	NOUN
dti-2520	92	23	by	by	ADP
dti-2520	92	24	the	the	DET
dti-2520	92	25	gut	gut	NOUN
dti-2520	92	26	microbiome	microbiome	NOUN
dti-2520	92	27	.	.	PUNCT
dti-2520	93	1	amps	amp	NOUN
dti-2520	93	2	=	=	PUNCT
dti-2520	93	3	antimicrobial	antimicrobial	ADJ
dti-2520	93	4	peptides	peptide	NOUN
dti-2520	93	5	;	;	PUNCT
dti-2520	93	6	dcs	dcs	PROPN
dti-2520	93	7	=	=	PROPN
dti-2520	93	8	dendritic	dendritic	ADJ
dti-2520	93	9	cells	cell	NOUN
dti-2520	93	10	;	;	PUNCT
dti-2520	93	11	ilc	ilc	NOUN
dti-2520	93	12	=	=	SYM
dti-2520	93	13	innate	innate	ADJ
dti-2520	93	14	lymphoid	lymphoid	ADJ
dti-2520	93	15	cell	cell	NOUN
dti-2520	93	16	;	;	PUNCT
dti-2520	93	17	lps	lps	PROPN
dti-2520	93	18	=	=	PUNCT
dti-2520	93	19	lipopolysaccharides	lipopolysaccharide	NOUN
dti-2520	93	20	;	;	PUNCT
dti-2520	93	21	pamps	pamp	NOUN
dti-2520	93	22	=	=	SYM
dti-2520	93	23	pathogen	pathogen	NOUN
dti-2520	93	24	associated	associate	VERB
dti-2520	93	25	molecular	molecular	ADJ
dti-2520	93	26	patterns	pattern	NOUN
dti-2520	93	27	;	;	PUNCT
dti-2520	93	28	scfas	scfas	NOUN
dti-2520	93	29	=	=	PUNCT
dti-2520	93	30	short	short	ADJ
dti-2520	93	31	-	-	PUNCT
dti-2520	93	32	chain	chain	NOUN
dti-2520	93	33	fatty	fatty	NOUN
dti-2520	93	34	acids	acid	NOUN
dti-2520	93	35	gut	gut	NOUN
dti-2520	93	36	microbiota	microbiota	NOUN
dti-2520	93	37	and	and	CCONJ
dti-2520	93	38	sepsis84	sepsis84	NOUN
dti-2520	94	1	©	©	ADP
dti-2520	94	2	2022	2022	NUM
dti-2520	95	1	the	the	DET
dti-2520	95	2	authors	author	NOUN
dti-2520	95	3	.	.	PUNCT
dti-2520	96	1	drug	drug	NOUN
dti-2520	96	2	target	target	NOUN
dti-2520	96	3	insights	insight	NOUN
dti-2520	96	4	issn	issn	VERB
dti-2520	96	5	1177	1177	NUM
dti-2520	96	6	-	-	SYM
dti-2520	96	7	3928	3928	NUM
dti-2520	96	8	www.aboutscience.eu/dti	www.aboutscience.eu/dti	VERB
dti-2520	96	9	the	the	DET
dti-2520	96	10	loss	loss	NOUN
dti-2520	96	11	of	of	ADP
dti-2520	96	12	membrane	membrane	NOUN
dti-2520	96	13	integrity	integrity	NOUN
dti-2520	96	14	and	and	CCONJ
dti-2520	96	15	translocation	translocation	NOUN
dti-2520	96	16	of	of	ADP
dti-2520	96	17	enteric	enteric	ADJ
dti-2520	96	18	bacteria	bacteria	NOUN
dti-2520	96	19	and	and	CCONJ
dti-2520	96	20	its	its	PRON
dti-2520	96	21	metabolites	metabolite	NOUN
dti-2520	96	22	from	from	ADP
dti-2520	96	23	the	the	DET
dti-2520	96	24	gut	gut	NOUN
dti-2520	96	25	to	to	ADP
dti-2520	96	26	the	the	DET
dti-2520	96	27	systemic	systemic	ADJ
dti-2520	96	28	circulation	circulation	NOUN
dti-2520	96	29	is	be	AUX
dti-2520	96	30	a	a	DET
dti-2520	96	31	hallmark	hallmark	ADJ
dti-2520	96	32	property	property	NOUN
dti-2520	96	33	of	of	ADP
dti-2520	96	34	sepsis	sepsis	NOUN
dti-2520	96	35	and	and	CCONJ
dti-2520	96	36	other	other	ADJ
dti-2520	96	37	inflammatory	inflammatory	ADJ
dti-2520	96	38	diseases	disease	NOUN
dti-2520	96	39	(	(	PUNCT
dti-2520	96	40	17	17	NUM
dti-2520	96	41	)	)	PUNCT
dti-2520	96	42	.	.	PUNCT
dti-2520	97	1	further	far	ADV
dti-2520	97	2	,	,	PUNCT
dti-2520	97	3	the	the	DET
dti-2520	97	4	antibiotics	antibiotic	NOUN
dti-2520	97	5	treatment	treatment	NOUN
dti-2520	97	6	may	may	AUX
dti-2520	97	7	change	change	VERB
dti-2520	97	8	the	the	DET
dti-2520	97	9	composition	composition	NOUN
dti-2520	97	10	and	and	CCONJ
dti-2520	97	11	diversity	diversity	NOUN
dti-2520	97	12	of	of	ADP
dti-2520	97	13	gut	gut	ADJ
dti-2520	97	14	microbiota	microbiota	NOUN
dti-2520	97	15	that	that	PRON
dti-2520	97	16	may	may	AUX
dti-2520	97	17	lead	lead	VERB
dti-2520	97	18	to	to	ADP
dti-2520	97	19	the	the	DET
dti-2520	97	20	translocation	translocation	NOUN
dti-2520	97	21	of	of	ADP
dti-2520	97	22	enteric	enteric	ADJ
dti-2520	97	23	bacteria	bacteria	NOUN
dti-2520	97	24	and	and	CCONJ
dti-2520	97	25	their	their	PRON
dti-2520	97	26	metabolites	metabolite	NOUN
dti-2520	97	27	across	across	ADP
dti-2520	97	28	the	the	DET
dti-2520	97	29	epithelium	epithelium	NOUN
dti-2520	97	30	,	,	PUNCT
dti-2520	97	31	which	which	PRON
dti-2520	97	32	may	may	AUX
dti-2520	97	33	provide	provide	VERB
dti-2520	97	34	vital	vital	ADJ
dti-2520	97	35	information	information	NOUN
dti-2520	97	36	about	about	ADP
dti-2520	97	37	the	the	DET
dti-2520	97	38	importance	importance	NOUN
dti-2520	97	39	of	of	ADP
dti-2520	97	40	the	the	DET
dti-2520	97	41	microbiota	microbiota	NOUN
dti-2520	97	42	in	in	ADP
dti-2520	97	43	host	host	NOUN
dti-2520	97	44	resistance	resistance	NOUN
dti-2520	97	45	against	against	ADP
dti-2520	97	46	pathogens	pathogen	NOUN
dti-2520	97	47	(	(	PUNCT
dti-2520	97	48	36	36	NUM
dti-2520	97	49	)	)	PUNCT
dti-2520	97	50	.	.	PUNCT
dti-2520	98	1	despite	despite	SCONJ
dti-2520	98	2	the	the	DET
dti-2520	98	3	recent	recent	ADJ
dti-2520	98	4	findings	finding	NOUN
dti-2520	98	5	of	of	ADP
dti-2520	98	6	gut	gut	NOUN
dti-2520	98	7	dysbiosis	dysbiosis	NOUN
dti-2520	98	8	to	to	ADP
dti-2520	98	9	sepsis	sepsis	NOUN
dti-2520	98	10	outcomes	outcome	NOUN
dti-2520	98	11	,	,	PUNCT
dti-2520	98	12	the	the	DET
dti-2520	98	13	precise	precise	ADJ
dti-2520	98	14	mechanisms	mechanism	NOUN
dti-2520	98	15	underlying	underlie	VERB
dti-2520	98	16	the	the	DET
dti-2520	98	17	protective	protective	ADJ
dti-2520	98	18	effects	effect	NOUN
dti-2520	98	19	of	of	ADP
dti-2520	98	20	gut	gut	NOUN
dti-2520	98	21	microbes	microbe	NOUN
dti-2520	98	22	in	in	ADP
dti-2520	98	23	sepsis	sepsis	NOUN
dti-2520	98	24	have	have	AUX
dti-2520	98	25	not	not	PART
dti-2520	98	26	been	be	AUX
dti-2520	98	27	well	well	ADV
dti-2520	98	28	defined	define	VERB
dti-2520	98	29	.	.	PUNCT
dti-2520	99	1	further	far	ADV
dti-2520	99	2	,	,	PUNCT
dti-2520	99	3	the	the	DET
dti-2520	99	4	role	role	NOUN
dti-2520	99	5	of	of	ADP
dti-2520	99	6	gut	gut	NOUN
dti-2520	99	7	microbiota	microbiota	NOUN
dti-2520	99	8	and	and	CCONJ
dti-2520	99	9	their	their	PRON
dti-2520	99	10	metabolites	metabolite	NOUN
dti-2520	99	11	in	in	ADP
dti-2520	99	12	modulating	modulate	VERB
dti-2520	99	13	the	the	DET
dti-2520	99	14	host	host	NOUN
dti-2520	99	15	mucosal	mucosal	NOUN
dti-2520	99	16	immune	immune	ADJ
dti-2520	99	17	response	response	NOUN
dti-2520	99	18	is	be	AUX
dti-2520	99	19	not	not	PART
dti-2520	99	20	well	well	ADV
dti-2520	99	21	known	know	VERB
dti-2520	99	22	.	.	PUNCT
dti-2520	100	1	more	more	ADV
dti-2520	100	2	importantly	importantly	ADV
dti-2520	100	3	,	,	PUNCT
dti-2520	100	4	at	at	ADP
dti-2520	100	5	present	present	ADJ
dti-2520	100	6	,	,	PUNCT
dti-2520	100	7	we	we	PRON
dti-2520	100	8	do	do	AUX
dti-2520	100	9	not	not	PART
dti-2520	100	10	have	have	VERB
dti-2520	100	11	diagnostic	diagnostic	ADJ
dti-2520	100	12	kits	kit	NOUN
dti-2520	100	13	or	or	CCONJ
dti-2520	100	14	therapies	therapy	NOUN
dti-2520	100	15	directed	direct	VERB
dti-2520	100	16	at	at	ADP
dti-2520	100	17	the	the	DET
dti-2520	100	18	gut	gut	NOUN
dti-2520	100	19	microbiome	microbiome	NOUN
dti-2520	100	20	that	that	PRON
dti-2520	100	21	could	could	AUX
dti-2520	100	22	be	be	AUX
dti-2520	100	23	implemented	implement	VERB
dti-2520	100	24	in	in	ADP
dti-2520	100	25	the	the	DET
dti-2520	100	26	clinical	clinical	ADJ
dti-2520	100	27	management	management	NOUN
dti-2520	100	28	of	of	ADP
dti-2520	100	29	sepsis	sepsis	NOUN
dti-2520	100	30	.	.	PUNCT
dti-2520	101	1	patients	patient	NOUN
dti-2520	101	2	in	in	ADP
dti-2520	101	3	the	the	DET
dti-2520	101	4	early	early	ADJ
dti-2520	101	5	stages	stage	NOUN
dti-2520	101	6	of	of	ADP
dti-2520	101	7	sepsis	sepsis	NOUN
dti-2520	101	8	manifest	manif	ADJ
dti-2520	101	9	differences	difference	NOUN
dti-2520	101	10	in	in	ADP
dti-2520	101	11	their	their	PRON
dti-2520	101	12	microbiome	microbiome	ADJ
dti-2520	101	13	composition	composition	NOUN
dti-2520	101	14	and	and	CCONJ
dti-2520	101	15	diversity	diversity	NOUN
dti-2520	101	16	as	as	SCONJ
dti-2520	101	17	compared	compare	VERB
dti-2520	101	18	to	to	ADP
dti-2520	101	19	critically	critically	ADV
dti-2520	101	20	ill	ill	ADJ
dti-2520	101	21	stages	stage	NOUN
dti-2520	101	22	of	of	ADP
dti-2520	101	23	sepsis	sepsis	NOUN
dti-2520	101	24	(	(	PUNCT
dti-2520	101	25	20	20	NUM
dti-2520	101	26	)	)	PUNCT
dti-2520	101	27	.	.	PUNCT
dti-2520	102	1	as	as	SCONJ
dti-2520	102	2	compared	compare	VERB
dti-2520	102	3	to	to	ADP
dti-2520	102	4	survivors	survivor	NOUN
dti-2520	102	5	,	,	PUNCT
dti-2520	102	6	non	non	ADJ
dti-2520	102	7	-	-	NOUN
dti-2520	102	8	survivors	survivor	NOUN
dti-2520	102	9	with	with	ADP
dti-2520	102	10	sepsis	sepsis	NOUN
dti-2520	102	11	have	have	AUX
dti-2520	102	12	pathogenic	pathogenic	ADJ
dti-2520	102	13	and	and	CCONJ
dti-2520	102	14	antibioticresistant	antibioticresistant	ADJ
dti-2520	102	15	bacterial	bacterial	ADJ
dti-2520	102	16	species	specie	NOUN
dti-2520	102	17	such	such	ADJ
dti-2520	102	18	as	as	ADP
dti-2520	102	19	clostridia	clostridia	NOUN
dti-2520	102	20	species	specie	NOUN
dti-2520	102	21	and	and	CCONJ
dti-2520	102	22	enterococcus	enterococcus	NOUN
dti-2520	102	23	species	specie	NOUN
dti-2520	102	24	(	(	PUNCT
dti-2520	102	25	37	37	NUM
dti-2520	102	26	)	)	PUNCT
dti-2520	102	27	.	.	PUNCT
dti-2520	103	1	use	use	NOUN
dti-2520	103	2	of	of	ADP
dti-2520	103	3	excessive	excessive	ADJ
dti-2520	103	4	antibiotics	antibiotic	NOUN
dti-2520	103	5	for	for	ADP
dti-2520	103	6	the	the	DET
dti-2520	103	7	treatment	treatment	NOUN
dti-2520	103	8	of	of	ADP
dti-2520	103	9	sepsis	sepsis	NOUN
dti-2520	103	10	patients	patient	NOUN
dti-2520	103	11	inclines	incline	VERB
dti-2520	103	12	to	to	PART
dti-2520	103	13	gut	gut	VERB
dti-2520	103	14	dysbiosis	dysbiosis	NOUN
dti-2520	103	15	and	and	CCONJ
dti-2520	103	16	a	a	DET
dti-2520	103	17	state	state	NOUN
dti-2520	103	18	of	of	ADP
dti-2520	103	19	immune	immune	ADJ
dti-2520	103	20	suppression	suppression	NOUN
dti-2520	103	21	,	,	PUNCT
dti-2520	103	22	with	with	ADP
dti-2520	103	23	subsequent	subsequent	ADJ
dti-2520	103	24	poor	poor	ADJ
dti-2520	103	25	outcomes	outcome	NOUN
dti-2520	103	26	in	in	ADP
dti-2520	103	27	the	the	DET
dti-2520	103	28	later	later	ADJ
dti-2520	103	29	course	course	NOUN
dti-2520	103	30	of	of	ADP
dti-2520	103	31	hospitalization	hospitalization	NOUN
dti-2520	103	32	during	during	ADP
dti-2520	103	33	sepsis	sepsis	NOUN
dti-2520	103	34	(	(	PUNCT
dti-2520	103	35	38	38	NUM
dti-2520	103	36	)	)	PUNCT
dti-2520	103	37	.	.	PUNCT
dti-2520	104	1	a	a	DET
dti-2520	104	2	study	study	NOUN
dti-2520	104	3	conducted	conduct	VERB
dti-2520	104	4	in	in	ADP
dti-2520	104	5	the	the	DET
dti-2520	104	6	murine	murine	ADJ
dti-2520	104	7	model	model	NOUN
dti-2520	104	8	of	of	ADP
dti-2520	104	9	sepsis	sepsis	NOUN
dti-2520	104	10	confirmed	confirm	VERB
dti-2520	104	11	the	the	DET
dti-2520	104	12	translocation	translocation	NOUN
dti-2520	104	13	of	of	ADP
dti-2520	104	14	bacteria	bacteria	NOUN
dti-2520	104	15	klebsiella	klebsiella	NOUN
dti-2520	104	16	pneumoniae	pneumoniae	ADJ
dti-2520	104	17	from	from	ADP
dti-2520	104	18	the	the	DET
dti-2520	104	19	gut	gut	NOUN
dti-2520	104	20	to	to	ADP
dti-2520	104	21	the	the	DET
dti-2520	104	22	systemic	systemic	ADJ
dti-2520	104	23	circulation	circulation	NOUN
dti-2520	104	24	(	(	PUNCT
dti-2520	104	25	35	35	NUM
dti-2520	104	26	)	)	PUNCT
dti-2520	104	27	.	.	PUNCT
dti-2520	105	1	a	a	DET
dti-2520	105	2	prospective	prospective	ADJ
dti-2520	105	3	cohort	cohort	NOUN
dti-2520	105	4	study	study	NOUN
dti-2520	105	5	conducted	conduct	VERB
dti-2520	105	6	on	on	ADP
dti-2520	105	7	71	71	NUM
dti-2520	105	8	preterm	preterm	ADJ
dti-2520	105	9	infants	infant	NOUN
dti-2520	105	10	with	with	ADP
dti-2520	105	11	sepsis	sepsis	NOUN
dti-2520	105	12	showed	show	VERB
dti-2520	105	13	domination	domination	NOUN
dti-2520	105	14	of	of	ADP
dti-2520	105	15	the	the	DET
dti-2520	105	16	gut	gut	NOUN
dti-2520	105	17	microbiota	microbiota	NOUN
dti-2520	105	18	with	with	ADP
dti-2520	105	19	bacilli	bacilli	NOUN
dti-2520	105	20	and	and	CCONJ
dti-2520	105	21	decreased	decrease	VERB
dti-2520	105	22	abundance	abundance	NOUN
dti-2520	105	23	of	of	ADP
dti-2520	105	24	anaerobic	anaerobic	ADJ
dti-2520	105	25	bacteria	bacteria	NOUN
dti-2520	105	26	(	(	PUNCT
dti-2520	105	27	39	39	NUM
dti-2520	105	28	)	)	PUNCT
dti-2520	105	29	.	.	PUNCT
dti-2520	106	1	a	a	DET
dti-2520	106	2	recent	recent	ADJ
dti-2520	106	3	study	study	NOUN
dti-2520	106	4	highlighted	highlight	VERB
dti-2520	106	5	that	that	SCONJ
dti-2520	106	6	gut	gut	VERB
dti-2520	106	7	dysbiosis	dysbiosis	NOUN
dti-2520	106	8	with	with	ADP
dti-2520	106	9	an	an	DET
dti-2520	106	10	accumulation	accumulation	NOUN
dti-2520	106	11	of	of	ADP
dti-2520	106	12	bacilli	bacilli	NOUN
dti-2520	106	13	(	(	PUNCT
dti-2520	106	14	largely	largely	ADV
dti-2520	106	15	coagulase	coagulase	ADJ
dti-2520	106	16	-	-	PUNCT
dti-2520	106	17	negative	negative	ADJ
dti-2520	106	18	staphylococci	staphylococci	NOUN
dti-2520	106	19	)	)	PUNCT
dti-2520	106	20	and	and	CCONJ
dti-2520	106	21	their	their	PRON
dti-2520	106	22	fermentation	fermentation	NOUN
dti-2520	106	23	metabolites	metabolite	NOUN
dti-2520	106	24	could	could	AUX
dti-2520	106	25	precede	precede	VERB
dti-2520	106	26	late	late	ADJ
dti-2520	106	27	-	-	PUNCT
dti-2520	106	28	onset	onset	NOUN
dti-2520	106	29	sepsis	sepsis	NOUN
dti-2520	106	30	(	(	PUNCT
dti-2520	106	31	40	40	NUM
dti-2520	106	32	)	)	PUNCT
dti-2520	106	33	.	.	PUNCT
dti-2520	107	1	a	a	DET
dti-2520	107	2	significant	significant	ADJ
dti-2520	107	3	reduction	reduction	NOUN
dti-2520	107	4	of	of	ADP
dti-2520	107	5	commensal	commensal	ADJ
dti-2520	107	6	bacteria	bacteria	NOUN
dti-2520	107	7	and	and	CCONJ
dti-2520	107	8	overgrowth	overgrowth	NOUN
dti-2520	107	9	of	of	ADP
dti-2520	107	10	enteric	enteric	ADJ
dti-2520	107	11	bacteria	bacteria	NOUN
dti-2520	107	12	may	may	AUX
dti-2520	107	13	lead	lead	VERB
dti-2520	107	14	to	to	ADP
dti-2520	107	15	overwhelming	overwhelming	ADJ
dti-2520	107	16	inflammation	inflammation	NOUN
dti-2520	107	17	and	and	CCONJ
dti-2520	107	18	inflammatory	inflammatory	ADJ
dti-2520	107	19	diseases	disease	NOUN
dti-2520	107	20	.	.	PUNCT
dti-2520	108	1	several	several	ADJ
dti-2520	108	2	studies	study	NOUN
dti-2520	108	3	have	have	AUX
dti-2520	108	4	highlighted	highlight	VERB
dti-2520	108	5	the	the	DET
dti-2520	108	6	importance	importance	NOUN
dti-2520	108	7	of	of	ADP
dti-2520	108	8	diverse	diverse	ADJ
dti-2520	108	9	and	and	CCONJ
dti-2520	108	10	balanced	balanced	ADJ
dti-2520	108	11	intestinal	intestinal	ADJ
dti-2520	108	12	microbiota	microbiota	NOUN
dti-2520	108	13	in	in	ADP
dti-2520	108	14	enhancing	enhance	VERB
dti-2520	108	15	the	the	DET
dti-2520	108	16	host	host	NOUN
dti-2520	108	17	’s	’s	PART
dti-2520	108	18	immunity	immunity	NOUN
dti-2520	108	19	to	to	ADP
dti-2520	108	20	intestinal	intestinal	ADJ
dti-2520	108	21	and	and	CCONJ
dti-2520	108	22	systemic	systemic	ADJ
dti-2520	108	23	pathogens	pathogen	NOUN
dti-2520	108	24	,	,	PUNCT
dti-2520	108	25	and	and	CCONJ
dti-2520	108	26	disturbing	disturb	VERB
dti-2520	108	27	this	this	DET
dti-2520	108	28	balance	balance	NOUN
dti-2520	108	29	is	be	AUX
dti-2520	108	30	likely	likely	ADJ
dti-2520	108	31	to	to	PART
dti-2520	108	32	increase	increase	VERB
dti-2520	108	33	the	the	DET
dti-2520	108	34	susceptibility	susceptibility	NOUN
dti-2520	108	35	to	to	ADP
dti-2520	108	36	sepsis	sepsis	NOUN
dti-2520	108	37	(	(	PUNCT
dti-2520	108	38	14,17	14,17	NUM
dti-2520	108	39	)	)	PUNCT
dti-2520	108	40	.	.	PUNCT
dti-2520	109	1	however	however	ADV
dti-2520	109	2	,	,	PUNCT
dti-2520	109	3	the	the	DET
dti-2520	109	4	role	role	NOUN
dti-2520	109	5	of	of	ADP
dti-2520	109	6	gut	gut	NOUN
dti-2520	109	7	microbiota	microbiota	NOUN
dti-2520	109	8	and	and	CCONJ
dti-2520	109	9	its	its	PRON
dti-2520	109	10	association	association	NOUN
dti-2520	109	11	with	with	ADP
dti-2520	109	12	the	the	DET
dti-2520	109	13	pathogenesis	pathogenesis	NOUN
dti-2520	109	14	of	of	ADP
dti-2520	109	15	sepsis	sepsis	NOUN
dti-2520	109	16	is	be	AUX
dti-2520	109	17	not	not	PART
dti-2520	109	18	yet	yet	ADV
dti-2520	109	19	fully	fully	ADV
dti-2520	109	20	understood	understand	VERB
dti-2520	109	21	.	.	PUNCT
dti-2520	110	1	moreover	moreover	ADV
dti-2520	110	2	,	,	PUNCT
dti-2520	110	3	association	association	NOUN
dti-2520	110	4	studies	study	NOUN
dti-2520	110	5	of	of	ADP
dti-2520	110	6	the	the	DET
dti-2520	110	7	gut	gut	NOUN
dti-2520	110	8	microbiota	microbiota	NOUN
dti-2520	110	9	with	with	ADP
dti-2520	110	10	clinical	clinical	ADJ
dti-2520	110	11	parameters	parameter	NOUN
dti-2520	110	12	and	and	CCONJ
dti-2520	110	13	the	the	DET
dti-2520	110	14	outcome	outcome	NOUN
dti-2520	110	15	of	of	ADP
dti-2520	110	16	patients	patient	NOUN
dti-2520	110	17	with	with	ADP
dti-2520	110	18	sepsis	sepsis	NOUN
dti-2520	110	19	are	be	AUX
dti-2520	110	20	urgently	urgently	ADV
dti-2520	110	21	needed	need	VERB
dti-2520	110	22	.	.	PUNCT
dti-2520	111	1	effects	effect	NOUN
dti-2520	111	2	of	of	ADP
dti-2520	111	3	gut	gut	NOUN
dti-2520	111	4	microbiota	microbiota	NOUN
dti-2520	111	5	in	in	ADP
dti-2520	111	6	modulating	modulate	VERB
dti-2520	111	7	the	the	DET
dti-2520	111	8	mucosal	mucosal	ADJ
dti-2520	111	9	immune	immune	ADJ
dti-2520	111	10	response	response	NOUN
dti-2520	111	11	the	the	DET
dti-2520	111	12	major	major	ADJ
dti-2520	111	13	components	component	NOUN
dti-2520	111	14	of	of	ADP
dti-2520	111	15	the	the	DET
dti-2520	111	16	immune	immune	ADJ
dti-2520	111	17	system	system	NOUN
dti-2520	111	18	that	that	PRON
dti-2520	111	19	are	be	AUX
dti-2520	111	20	involved	involve	VERB
dti-2520	111	21	in	in	ADP
dti-2520	111	22	protecting	protect	VERB
dti-2520	111	23	the	the	DET
dti-2520	111	24	host	host	NOUN
dti-2520	111	25	against	against	ADP
dti-2520	111	26	diverse	diverse	ADJ
dti-2520	111	27	pathogens	pathogen	NOUN
dti-2520	111	28	are	be	AUX
dti-2520	111	29	immune	immune	ADJ
dti-2520	111	30	cells	cell	NOUN
dti-2520	111	31	,	,	PUNCT
dti-2520	111	32	tissues	tissue	NOUN
dti-2520	111	33	,	,	PUNCT
dti-2520	111	34	organs	organ	NOUN
dti-2520	111	35	,	,	PUNCT
dti-2520	111	36	soluble	soluble	ADJ
dti-2520	111	37	mediators	mediator	NOUN
dti-2520	111	38	such	such	ADJ
dti-2520	111	39	as	as	ADP
dti-2520	111	40	cytokines	cytokine	NOUN
dti-2520	111	41	,	,	PUNCT
dti-2520	111	42	and	and	CCONJ
dti-2520	111	43	cell	cell	NOUN
dti-2520	111	44	receptors	receptor	NOUN
dti-2520	111	45	.	.	PUNCT
dti-2520	112	1	the	the	DET
dti-2520	112	2	gastrointestinal	gastrointestinal	ADJ
dti-2520	112	3	tract	tract	NOUN
dti-2520	112	4	is	be	AUX
dti-2520	112	5	considered	consider	VERB
dti-2520	112	6	the	the	DET
dti-2520	112	7	most	most	ADV
dti-2520	112	8	important	important	ADJ
dti-2520	112	9	immunological	immunological	ADJ
dti-2520	112	10	organ	organ	NOUN
dti-2520	112	11	in	in	ADP
dti-2520	112	12	the	the	DET
dti-2520	112	13	body	body	NOUN
dti-2520	112	14	because	because	SCONJ
dti-2520	112	15	it	it	PRON
dti-2520	112	16	harbors	harbor	VERB
dti-2520	112	17	up	up	ADP
dti-2520	112	18	to	to	PART
dti-2520	112	19	70	70	NUM
dti-2520	112	20	%	%	NOUN
dti-2520	112	21	of	of	ADP
dti-2520	112	22	the	the	DET
dti-2520	112	23	body	body	NOUN
dti-2520	112	24	’s	’s	PART
dti-2520	112	25	lymphocyte	lymphocyte	ADJ
dti-2520	112	26	population	population	NOUN
dti-2520	112	27	.	.	PUNCT
dti-2520	113	1	the	the	DET
dti-2520	113	2	intestine	intestine	ADJ
dti-2520	113	3	mucosal	mucosal	ADJ
dti-2520	113	4	immune	immune	ADJ
dti-2520	113	5	system	system	NOUN
dti-2520	113	6	is	be	AUX
dti-2520	113	7	an	an	DET
dti-2520	113	8	integral	integral	ADJ
dti-2520	113	9	component	component	NOUN
dti-2520	113	10	of	of	ADP
dti-2520	113	11	innate	innate	ADJ
dti-2520	113	12	and	and	CCONJ
dti-2520	113	13	adaptive	adaptive	ADJ
dti-2520	113	14	immunity	immunity	NOUN
dti-2520	113	15	that	that	PRON
dti-2520	113	16	includes	include	VERB
dti-2520	113	17	three	three	NUM
dti-2520	113	18	different	different	ADJ
dti-2520	113	19	mucosal	mucosal	ADJ
dti-2520	113	20	lymphoid	lymphoid	NOUN
dti-2520	113	21	structures	structure	NOUN
dti-2520	113	22	:	:	PUNCT
dti-2520	113	23	peyer	peyer	NOUN
dti-2520	113	24	’s	’s	PART
dti-2520	113	25	patches	patch	NOUN
dti-2520	113	26	(	(	PUNCT
dti-2520	113	27	pp	pp	PROPN
dti-2520	113	28	)	)	PUNCT
dti-2520	113	29	,	,	PUNCT
dti-2520	113	30	the	the	DET
dti-2520	113	31	lamina	lamina	ADJ
dti-2520	113	32	propria	propria	PROPN
dti-2520	113	33	(	(	PUNCT
dti-2520	113	34	lp	lp	NOUN
dti-2520	113	35	)	)	PUNCT
dti-2520	113	36	,	,	PUNCT
dti-2520	113	37	and	and	CCONJ
dti-2520	113	38	the	the	DET
dti-2520	113	39	epithelia	epithelia	PROPN
dti-2520	113	40	.	.	PUNCT
dti-2520	114	1	beneath	beneath	ADP
dti-2520	114	2	the	the	DET
dti-2520	114	3	epithelium	epithelium	NOUN
dti-2520	114	4	,	,	PUNCT
dti-2520	114	5	the	the	DET
dti-2520	114	6	lp	lp	PROPN
dti-2520	114	7	harbors	harbor	VERB
dti-2520	114	8	dendritic	dendritic	ADJ
dti-2520	114	9	cells	cell	NOUN
dti-2520	114	10	(	(	PUNCT
dti-2520	114	11	dcs	dcs	PROPN
dti-2520	114	12	)	)	PUNCT
dti-2520	114	13	,	,	PUNCT
dti-2520	114	14	which	which	PRON
dti-2520	114	15	are	be	AUX
dti-2520	114	16	potent	potent	ADJ
dti-2520	114	17	antigen	antigen	ADV
dti-2520	114	18	-	-	PUNCT
dti-2520	114	19	presenting	present	VERB
dti-2520	114	20	cells	cell	NOUN
dti-2520	114	21	(	(	PUNCT
dti-2520	114	22	apcs	apc	NOUN
dti-2520	114	23	)	)	PUNCT
dti-2520	114	24	,	,	PUNCT
dti-2520	114	25	and	and	CCONJ
dti-2520	114	26	the	the	DET
dti-2520	114	27	gut	gut	NOUN
dti-2520	114	28	-	-	PUNCT
dti-2520	114	29	associated	associate	VERB
dti-2520	114	30	lymphoid	lymphoid	ADJ
dti-2520	114	31	tissue	tissue	NOUN
dti-2520	114	32	(	(	PUNCT
dti-2520	114	33	galt	galt	PROPN
dti-2520	114	34	)	)	PUNCT
dti-2520	114	35	,	,	PUNCT
dti-2520	114	36	which	which	PRON
dti-2520	114	37	includes	include	VERB
dti-2520	114	38	pp	pp	ADV
dti-2520	114	39	,	,	PUNCT
dti-2520	114	40	lymphocytes	lymphocyte	NOUN
dti-2520	114	41	,	,	PUNCT
dti-2520	114	42	and	and	CCONJ
dti-2520	114	43	intraepithelial	intraepithelial	ADJ
dti-2520	114	44	lymphocytes	lymphocyte	NOUN
dti-2520	114	45	(	(	PUNCT
dti-2520	114	46	iels	iel	NOUN
dti-2520	114	47	)	)	PUNCT
dti-2520	114	48	.	.	PUNCT
dti-2520	115	1	iels	iel	NOUN
dti-2520	115	2	are	be	AUX
dti-2520	115	3	the	the	DET
dti-2520	115	4	first	first	ADJ
dti-2520	115	5	immune	immune	ADJ
dti-2520	115	6	cells	cell	NOUN
dti-2520	115	7	that	that	PRON
dti-2520	115	8	encounter	encounter	VERB
dti-2520	115	9	invading	invade	VERB
dti-2520	115	10	pathogens	pathogen	NOUN
dti-2520	115	11	through	through	ADP
dti-2520	115	12	an	an	DET
dti-2520	115	13	epithelial	epithelial	ADJ
dti-2520	115	14	surface	surface	NOUN
dti-2520	115	15	of	of	ADP
dti-2520	115	16	the	the	DET
dti-2520	115	17	intestinal	intestinal	ADJ
dti-2520	115	18	tract	tract	NOUN
dti-2520	115	19	,	,	PUNCT
dti-2520	115	20	urinogenital	urinogenital	ADJ
dti-2520	115	21	tract	tract	NOUN
dti-2520	115	22	,	,	PUNCT
dti-2520	115	23	and	and	CCONJ
dti-2520	115	24	respiratory	respiratory	ADJ
dti-2520	115	25	tract	tract	NOUN
dti-2520	115	26	.	.	PUNCT
dti-2520	116	1	the	the	DET
dti-2520	116	2	mucus	mucus	NOUN
dti-2520	116	3	layer	layer	NOUN
dti-2520	116	4	present	present	ADJ
dti-2520	116	5	on	on	ADP
dti-2520	116	6	the	the	DET
dti-2520	116	7	surface	surface	NOUN
dti-2520	116	8	of	of	ADP
dti-2520	116	9	epithelial	epithelial	ADJ
dti-2520	116	10	cells	cell	NOUN
dti-2520	116	11	along	along	ADV
dti-2520	116	12	with	with	ADP
dti-2520	116	13	secreting	secrete	VERB
dti-2520	116	14	antimicrobial	antimicrobial	ADJ
dti-2520	116	15	peptides	peptide	NOUN
dti-2520	116	16	(	(	PUNCT
dti-2520	116	17	amps	amp	NOUN
dti-2520	116	18	)	)	PUNCT
dti-2520	116	19	in	in	ADP
dti-2520	116	20	response	response	NOUN
dti-2520	116	21	to	to	ADP
dti-2520	116	22	bacteria	bacteria	NOUN
dti-2520	116	23	or	or	CCONJ
dti-2520	116	24	pathogens	pathogen	NOUN
dti-2520	116	25	primarily	primarily	ADV
dti-2520	116	26	contributes	contribute	VERB
dti-2520	116	27	to	to	ADP
dti-2520	116	28	the	the	DET
dti-2520	116	29	intestinal	intestinal	ADJ
dti-2520	116	30	innate	innate	ADJ
dti-2520	116	31	host	host	NOUN
dti-2520	116	32	defense	defense	NOUN
dti-2520	116	33	system	system	NOUN
dti-2520	116	34	(	(	PUNCT
dti-2520	116	35	1	1	NUM
dti-2520	116	36	)	)	PUNCT
dti-2520	116	37	.	.	PUNCT
dti-2520	117	1	the	the	DET
dti-2520	117	2	intestinal	intestinal	ADJ
dti-2520	117	3	epithelial	epithelial	ADJ
dti-2520	117	4	cells	cell	NOUN
dti-2520	117	5	are	be	AUX
dti-2520	117	6	directly	directly	ADV
dti-2520	117	7	involved	involve	VERB
dti-2520	117	8	in	in	ADP
dti-2520	117	9	defense	defense	NOUN
dti-2520	117	10	against	against	ADP
dti-2520	117	11	invading	invade	VERB
dti-2520	117	12	pathogens	pathogen	NOUN
dti-2520	117	13	and	and	CCONJ
dti-2520	117	14	also	also	ADV
dti-2520	117	15	send	send	VERB
dti-2520	117	16	signals	signal	NOUN
dti-2520	117	17	to	to	ADP
dti-2520	117	18	the	the	DET
dti-2520	117	19	mucosal	mucosal	ADJ
dti-2520	117	20	immune	immune	ADJ
dti-2520	117	21	system	system	NOUN
dti-2520	117	22	by	by	ADP
dti-2520	117	23	producing	produce	VERB
dti-2520	117	24	soluble	soluble	ADJ
dti-2520	117	25	mediators	mediator	NOUN
dti-2520	117	26	such	such	ADJ
dti-2520	117	27	as	as	ADP
dti-2520	117	28	cytokines	cytokine	NOUN
dti-2520	117	29	and	and	CCONJ
dti-2520	117	30	chemokines	chemokine	NOUN
dti-2520	117	31	(	(	PUNCT
dti-2520	117	32	41	41	NUM
dti-2520	117	33	)	)	PUNCT
dti-2520	117	34	.	.	PUNCT
dti-2520	118	1	the	the	DET
dti-2520	118	2	innate	innate	ADJ
dti-2520	118	3	lymphoid	lymphoid	ADJ
dti-2520	118	4	cells	cell	NOUN
dti-2520	118	5	(	(	PUNCT
dti-2520	118	6	ilcs	ilcs	NOUN
dti-2520	118	7	)	)	PUNCT
dti-2520	118	8	located	locate	VERB
dti-2520	118	9	in	in	ADP
dti-2520	118	10	the	the	DET
dti-2520	118	11	epithelial	epithelial	ADJ
dti-2520	118	12	cells	cell	NOUN
dti-2520	118	13	also	also	ADV
dti-2520	118	14	work	work	VERB
dti-2520	118	15	as	as	ADP
dti-2520	118	16	the	the	DET
dti-2520	118	17	first	first	ADJ
dti-2520	118	18	line	line	NOUN
dti-2520	118	19	of	of	ADP
dti-2520	118	20	defense	defense	NOUN
dti-2520	118	21	and	and	CCONJ
dti-2520	118	22	get	get	AUX
dti-2520	118	23	activated	activate	VERB
dti-2520	118	24	in	in	ADP
dti-2520	118	25	response	response	NOUN
dti-2520	118	26	to	to	ADP
dti-2520	118	27	stimuli	stimulus	NOUN
dti-2520	118	28	.	.	PUNCT
dti-2520	119	1	once	once	ADV
dti-2520	119	2	ilcs	ilcs	NOUN
dti-2520	119	3	get	get	AUX
dti-2520	119	4	activated	activate	VERB
dti-2520	119	5	it	it	PRON
dti-2520	119	6	produces	produce	VERB
dti-2520	119	7	various	various	ADJ
dti-2520	119	8	soluble	soluble	ADJ
dti-2520	119	9	mediators	mediator	NOUN
dti-2520	119	10	such	such	ADJ
dti-2520	119	11	as	as	ADP
dti-2520	119	12	cytokines	cytokine	NOUN
dti-2520	119	13	and	and	CCONJ
dti-2520	119	14	chemokines	chemokine	NOUN
dti-2520	119	15	that	that	PRON
dti-2520	119	16	are	be	AUX
dti-2520	119	17	essentially	essentially	ADV
dti-2520	119	18	required	require	VERB
dti-2520	119	19	for	for	ADP
dti-2520	119	20	the	the	DET
dti-2520	119	21	development	development	NOUN
dti-2520	119	22	and	and	CCONJ
dti-2520	119	23	maturation	maturation	NOUN
dti-2520	119	24	of	of	ADP
dti-2520	119	25	the	the	DET
dti-2520	119	26	mucosal	mucosal	ADJ
dti-2520	119	27	immune	immune	ADJ
dti-2520	119	28	system	system	NOUN
dti-2520	119	29	(	(	PUNCT
dti-2520	119	30	42	42	NUM
dti-2520	119	31	)	)	PUNCT
dti-2520	119	32	.	.	PUNCT
dti-2520	120	1	the	the	DET
dti-2520	120	2	composition	composition	NOUN
dti-2520	120	3	and	and	CCONJ
dti-2520	120	4	diversity	diversity	NOUN
dti-2520	120	5	of	of	ADP
dti-2520	120	6	gut	gut	NOUN
dti-2520	120	7	microbiota	microbiota	NOUN
dti-2520	120	8	are	be	AUX
dti-2520	120	9	vital	vital	ADJ
dti-2520	120	10	in	in	ADP
dti-2520	120	11	maintaining	maintain	VERB
dti-2520	120	12	intestinal	intestinal	ADJ
dti-2520	120	13	homeostasis	homeostasis	NOUN
dti-2520	120	14	in	in	ADP
dti-2520	120	15	mammals	mammal	NOUN
dti-2520	120	16	.	.	PUNCT
dti-2520	121	1	dysbiosis	dysbiosis	NOUN
dti-2520	121	2	of	of	ADP
dti-2520	121	3	gut	gut	NOUN
dti-2520	121	4	microbiota	microbiota	NOUN
dti-2520	121	5	occurs	occur	VERB
dti-2520	121	6	due	due	ADJ
dti-2520	121	7	to	to	ADP
dti-2520	121	8	excessive	excessive	ADJ
dti-2520	121	9	use	use	NOUN
dti-2520	121	10	of	of	ADP
dti-2520	121	11	antibiotics	antibiotic	NOUN
dti-2520	121	12	during	during	ADP
dti-2520	121	13	inflammatory	inflammatory	ADJ
dti-2520	121	14	conditions	condition	NOUN
dti-2520	121	15	and	and	CCONJ
dti-2520	121	16	sepsis	sepsis	NOUN
dti-2520	121	17	may	may	AUX
dti-2520	121	18	lead	lead	VERB
dti-2520	121	19	to	to	ADP
dti-2520	121	20	the	the	DET
dti-2520	121	21	uncontrolled	uncontrolled	ADJ
dti-2520	121	22	production	production	NOUN
dti-2520	121	23	of	of	ADP
dti-2520	121	24	inflammatory	inflammatory	ADJ
dti-2520	121	25	mediators	mediator	NOUN
dti-2520	121	26	and	and	CCONJ
dti-2520	121	27	overwhelming	overwhelming	ADJ
dti-2520	121	28	activation	activation	NOUN
dti-2520	121	29	of	of	ADP
dti-2520	121	30	innate	innate	ADJ
dti-2520	121	31	immune	immune	ADJ
dti-2520	121	32	cells	cell	NOUN
dti-2520	121	33	.	.	PUNCT
dti-2520	122	1	in	in	ADP
dti-2520	122	2	addition	addition	NOUN
dti-2520	122	3	,	,	PUNCT
dti-2520	122	4	the	the	DET
dti-2520	122	5	adaptive	adaptive	ADJ
dti-2520	122	6	immune	immune	ADJ
dti-2520	122	7	system	system	NOUN
dti-2520	122	8	of	of	ADP
dti-2520	122	9	the	the	DET
dti-2520	122	10	gut	gut	NOUN
dti-2520	122	11	contributes	contribute	VERB
dti-2520	122	12	to	to	ADP
dti-2520	122	13	intestinal	intestinal	ADJ
dti-2520	122	14	barrier	barrier	NOUN
dti-2520	122	15	defense	defense	NOUN
dti-2520	122	16	by	by	ADP
dti-2520	122	17	secreting	secrete	VERB
dti-2520	122	18	immunoglobulins	immunoglobulin	NOUN
dti-2520	122	19	(	(	PUNCT
dti-2520	122	20	ig	ig	PROPN
dti-2520	122	21	)	)	PUNCT
dti-2520	122	22	.	.	PUNCT
dti-2520	123	1	the	the	DET
dti-2520	123	2	secreted	secrete	VERB
dti-2520	123	3	ig	ig	PROPN
dti-2520	123	4	by	by	ADP
dti-2520	123	5	the	the	DET
dti-2520	123	6	activated	activate	VERB
dti-2520	123	7	b	b	PROPN
dti-2520	123	8	cells	cell	NOUN
dti-2520	123	9	in	in	ADP
dti-2520	123	10	response	response	NOUN
dti-2520	123	11	to	to	ADP
dti-2520	123	12	invading	invade	VERB
dti-2520	123	13	pathogens	pathogen	NOUN
dti-2520	123	14	into	into	ADP
dti-2520	123	15	the	the	DET
dti-2520	123	16	intestinal	intestinal	ADJ
dti-2520	123	17	lumen	luman	NOUN
dti-2520	123	18	neutralize	neutralize	VERB
dti-2520	123	19	the	the	DET
dti-2520	123	20	pathogenic	pathogenic	ADJ
dti-2520	123	21	microorganism	microorganism	NOUN
dti-2520	123	22	and	and	CCONJ
dti-2520	123	23	protect	protect	VERB
dti-2520	123	24	the	the	DET
dti-2520	123	25	mucosal	mucosal	NOUN
dti-2520	123	26	tissue	tissue	NOUN
dti-2520	123	27	(	(	PUNCT
dti-2520	123	28	43	43	NUM
dti-2520	123	29	)	)	PUNCT
dti-2520	123	30	.	.	PUNCT
dti-2520	124	1	the	the	DET
dti-2520	124	2	role	role	NOUN
dti-2520	124	3	of	of	ADP
dti-2520	124	4	gut	gut	NOUN
dti-2520	124	5	microbiota	microbiota	NOUN
dti-2520	124	6	in	in	ADP
dti-2520	124	7	shaping	shape	VERB
dti-2520	124	8	the	the	DET
dti-2520	124	9	host	host	NOUN
dti-2520	124	10	mucosal	mucosal	NOUN
dti-2520	124	11	immune	immune	ADJ
dti-2520	124	12	response	response	NOUN
dti-2520	124	13	is	be	AUX
dti-2520	124	14	confirmed	confirm	VERB
dti-2520	124	15	by	by	ADP
dti-2520	124	16	several	several	ADJ
dti-2520	124	17	studies	study	NOUN
dti-2520	124	18	(	(	PUNCT
dti-2520	124	19	24	24	NUM
dti-2520	124	20	)	)	PUNCT
dti-2520	124	21	.	.	PUNCT
dti-2520	125	1	the	the	DET
dti-2520	125	2	various	various	ADJ
dti-2520	125	3	metabolites	metabolite	NOUN
dti-2520	125	4	such	such	ADJ
dti-2520	125	5	as	as	ADP
dti-2520	125	6	scfas	scfas	NOUN
dti-2520	125	7	and	and	CCONJ
dti-2520	125	8	tryptophan	tryptophan	NOUN
dti-2520	125	9	decomposition	decomposition	NOUN
dti-2520	125	10	metabolites	metabolite	NOUN
dti-2520	125	11	produced	produce	VERB
dti-2520	125	12	by	by	ADP
dti-2520	125	13	gut	gut	NOUN
dti-2520	125	14	microbiota	microbiota	NOUN
dti-2520	125	15	are	be	AUX
dti-2520	125	16	required	require	VERB
dti-2520	125	17	to	to	PART
dti-2520	125	18	stimulate	stimulate	VERB
dti-2520	125	19	ilcs	ilcs	NOUN
dti-2520	125	20	and	and	CCONJ
dti-2520	125	21	enhance	enhance	VERB
dti-2520	125	22	gut	gut	NOUN
dti-2520	125	23	integrity	integrity	NOUN
dti-2520	125	24	(	(	PUNCT
dti-2520	125	25	44	44	NUM
dti-2520	125	26	)	)	PUNCT
dti-2520	125	27	.	.	PUNCT
dti-2520	126	1	iels	iel	NOUN
dti-2520	126	2	are	be	AUX
dti-2520	126	3	considered	consider	VERB
dti-2520	126	4	an	an	DET
dti-2520	126	5	important	important	ADJ
dti-2520	126	6	player	player	NOUN
dti-2520	126	7	in	in	ADP
dti-2520	126	8	the	the	DET
dti-2520	126	9	adaptive	adaptive	ADJ
dti-2520	126	10	immune	immune	ADJ
dti-2520	126	11	response	response	NOUN
dti-2520	126	12	against	against	ADP
dti-2520	126	13	invading	invade	VERB
dti-2520	126	14	pathogens	pathogen	NOUN
dti-2520	126	15	(	(	PUNCT
dti-2520	126	16	45	45	NUM
dti-2520	126	17	)	)	PUNCT
dti-2520	126	18	.	.	PUNCT
dti-2520	127	1	they	they	PRON
dti-2520	127	2	are	be	AUX
dti-2520	127	3	rich	rich	ADJ
dti-2520	127	4	in	in	ADP
dti-2520	127	5	αβ+	αβ+	NOUN
dti-2520	127	6	and	and	CCONJ
dti-2520	127	7	γδ+	γδ+	PROPN
dti-2520	127	8	t	t	PROPN
dti-2520	127	9	-	-	PUNCT
dti-2520	127	10	cell	cell	NOUN
dti-2520	127	11	populations	population	NOUN
dti-2520	127	12	that	that	PRON
dti-2520	127	13	are	be	AUX
dti-2520	127	14	required	require	VERB
dti-2520	127	15	to	to	PART
dti-2520	127	16	protect	protect	VERB
dti-2520	127	17	against	against	ADP
dti-2520	127	18	germs	germ	NOUN
dti-2520	127	19	and	and	CCONJ
dti-2520	127	20	pathogens	pathogen	NOUN
dti-2520	127	21	during	during	ADP
dti-2520	127	22	inflammation	inflammation	NOUN
dti-2520	127	23	(	(	PUNCT
dti-2520	127	24	46	46	NUM
dti-2520	127	25	)	)	PUNCT
dti-2520	127	26	.	.	PUNCT
dti-2520	128	1	iels	iel	NOUN
dti-2520	128	2	showed	show	VERB
dti-2520	128	3	a	a	DET
dti-2520	128	4	diverse	diverse	ADJ
dti-2520	128	5	immune	immune	ADJ
dti-2520	128	6	response	response	NOUN
dti-2520	128	7	when	when	SCONJ
dti-2520	128	8	they	they	PRON
dti-2520	128	9	get	get	AUX
dti-2520	128	10	activated	activate	VERB
dti-2520	128	11	with	with	ADP
dti-2520	128	12	stimuli	stimulus	NOUN
dti-2520	128	13	.	.	PUNCT
dti-2520	129	1	once	once	SCONJ
dti-2520	129	2	iels	iel	NOUN
dti-2520	129	3	are	be	AUX
dti-2520	129	4	activated	activate	VERB
dti-2520	129	5	,	,	PUNCT
dti-2520	129	6	they	they	PRON
dti-2520	129	7	express	express	VERB
dti-2520	129	8	cytokines	cytokine	NOUN
dti-2520	129	9	such	such	ADJ
dti-2520	129	10	as	as	ADP
dti-2520	129	11	interferon	interferon	ADJ
dti-2520	129	12	-	-	PUNCT
dti-2520	129	13	γ	γ	NOUN
dti-2520	129	14	and	and	CCONJ
dti-2520	129	15	growth	growth	NOUN
dti-2520	129	16	factor	factor	NOUN
dti-2520	129	17	,	,	PUNCT
dti-2520	129	18	to	to	PART
dti-2520	129	19	protect	protect	VERB
dti-2520	129	20	epithelial	epithelial	ADJ
dti-2520	129	21	cells	cell	NOUN
dti-2520	129	22	from	from	ADP
dti-2520	129	23	injury	injury	NOUN
dti-2520	129	24	.	.	PUNCT
dti-2520	130	1	recently	recently	ADV
dti-2520	130	2	,	,	PUNCT
dti-2520	130	3	the	the	DET
dti-2520	130	4	association	association	NOUN
dti-2520	130	5	of	of	ADP
dti-2520	130	6	gut	gut	ADJ
dti-2520	130	7	microbiota	microbiota	NOUN
dti-2520	130	8	with	with	ADP
dti-2520	130	9	the	the	DET
dti-2520	130	10	development	development	NOUN
dti-2520	130	11	of	of	ADP
dti-2520	130	12	host	host	NOUN
dti-2520	130	13	immunity	immunity	NOUN
dti-2520	130	14	has	have	AUX
dti-2520	130	15	been	be	AUX
dti-2520	130	16	confirmed	confirm	VERB
dti-2520	130	17	by	by	ADP
dti-2520	130	18	several	several	ADJ
dti-2520	130	19	studies	study	NOUN
dti-2520	130	20	.	.	PUNCT
dti-2520	131	1	colonization	colonization	NOUN
dti-2520	131	2	of	of	ADP
dti-2520	131	3	commensal	commensal	ADJ
dti-2520	131	4	bacteria	bacteria	NOUN
dti-2520	131	5	in	in	ADP
dti-2520	131	6	early	early	ADJ
dti-2520	131	7	life	life	NOUN
dti-2520	131	8	is	be	AUX
dti-2520	131	9	important	important	ADJ
dti-2520	131	10	for	for	ADP
dti-2520	131	11	the	the	DET
dti-2520	131	12	metabolism	metabolism	NOUN
dti-2520	131	13	of	of	ADP
dti-2520	131	14	essential	essential	ADJ
dti-2520	131	15	nutrients	nutrient	NOUN
dti-2520	131	16	required	require	VERB
dti-2520	131	17	for	for	ADP
dti-2520	131	18	the	the	DET
dti-2520	131	19	host	host	NOUN
dti-2520	131	20	,	,	PUNCT
dti-2520	131	21	for	for	ADP
dti-2520	131	22	gut	gut	NOUN
dti-2520	131	23	development	development	NOUN
dti-2520	131	24	,	,	PUNCT
dti-2520	131	25	and	and	CCONJ
dti-2520	131	26	for	for	ADP
dti-2520	131	27	the	the	DET
dti-2520	131	28	maturation	maturation	NOUN
dti-2520	131	29	of	of	ADP
dti-2520	131	30	the	the	DET
dti-2520	131	31	innate	innate	ADJ
dti-2520	131	32	and	and	CCONJ
dti-2520	131	33	adaptive	adaptive	ADJ
dti-2520	131	34	immune	immune	ADJ
dti-2520	131	35	system	system	NOUN
dti-2520	131	36	(	(	PUNCT
dti-2520	131	37	47	47	NUM
dti-2520	131	38	)	)	PUNCT
dti-2520	131	39	.	.	PUNCT
dti-2520	132	1	a	a	DET
dti-2520	132	2	study	study	NOUN
dti-2520	132	3	conducted	conduct	VERB
dti-2520	132	4	in	in	ADP
dti-2520	132	5	germ	germ	NOUN
dti-2520	132	6	-	-	PUNCT
dti-2520	132	7	free	free	ADJ
dti-2520	132	8	(	(	PUNCT
dti-2520	132	9	gf	gf	NOUN
dti-2520	132	10	)	)	PUNCT
dti-2520	132	11	animals	animal	NOUN
dti-2520	132	12	showed	show	VERB
dti-2520	132	13	that	that	SCONJ
dti-2520	132	14	colonization	colonization	NOUN
dti-2520	132	15	of	of	ADP
dti-2520	132	16	gut	gut	NOUN
dti-2520	132	17	microbiota	microbiota	NOUN
dti-2520	132	18	in	in	ADP
dti-2520	132	19	the	the	DET
dti-2520	132	20	early	early	ADJ
dti-2520	132	21	stages	stage	NOUN
dti-2520	132	22	of	of	ADP
dti-2520	132	23	life	life	NOUN
dti-2520	132	24	is	be	AUX
dti-2520	132	25	crucial	crucial	ADJ
dti-2520	132	26	for	for	ADP
dti-2520	132	27	the	the	DET
dti-2520	132	28	optimum	optimum	ADJ
dti-2520	132	29	development	development	NOUN
dti-2520	132	30	and	and	CCONJ
dti-2520	132	31	maturation	maturation	NOUN
dti-2520	132	32	of	of	ADP
dti-2520	132	33	the	the	DET
dti-2520	132	34	immune	immune	ADJ
dti-2520	132	35	system	system	NOUN
dti-2520	132	36	(	(	PUNCT
dti-2520	132	37	48	48	NUM
dti-2520	132	38	)	)	PUNCT
dti-2520	132	39	.	.	PUNCT
dti-2520	133	1	early	early	ADJ
dti-2520	133	2	studies	study	NOUN
dti-2520	133	3	on	on	ADP
dti-2520	133	4	gf	gf	NOUN
dti-2520	133	5	animals	animal	NOUN
dti-2520	133	6	showed	show	VERB
dti-2520	133	7	that	that	SCONJ
dti-2520	133	8	the	the	DET
dti-2520	133	9	lack	lack	NOUN
dti-2520	133	10	of	of	ADP
dti-2520	133	11	colonization	colonization	NOUN
dti-2520	133	12	of	of	ADP
dti-2520	133	13	commensal	commensal	NOUN
dti-2520	133	14	microbes	microbe	NOUN
dti-2520	133	15	is	be	AUX
dti-2520	133	16	associated	associate	VERB
dti-2520	133	17	with	with	ADP
dti-2520	133	18	significant	significant	ADJ
dti-2520	133	19	intestinal	intestinal	ADJ
dti-2520	133	20	defects	defect	NOUN
dti-2520	133	21	in	in	ADP
dti-2520	133	22	immune	immune	ADJ
dti-2520	133	23	cell	cell	NOUN
dti-2520	133	24	development	development	NOUN
dti-2520	133	25	and	and	CCONJ
dti-2520	133	26	functions	function	NOUN
dti-2520	133	27	(	(	PUNCT
dti-2520	133	28	49	49	NUM
dti-2520	133	29	)	)	PUNCT
dti-2520	133	30	.	.	PUNCT
dti-2520	134	1	intestinal	intestinal	ADJ
dti-2520	134	2	microbial	microbial	ADJ
dti-2520	134	3	colonization	colonization	NOUN
dti-2520	134	4	during	during	ADP
dti-2520	134	5	the	the	DET
dti-2520	134	6	early	early	ADJ
dti-2520	134	7	-	-	PUNCT
dti-2520	134	8	life	life	NOUN
dti-2520	134	9	stage	stage	NOUN
dti-2520	134	10	is	be	AUX
dti-2520	134	11	critical	critical	ADJ
dti-2520	134	12	for	for	ADP
dti-2520	134	13	the	the	DET
dti-2520	134	14	development	development	NOUN
dti-2520	134	15	of	of	ADP
dti-2520	134	16	αβ	αβ	INTJ
dti-2520	134	17	and	and	CCONJ
dti-2520	134	18	γδ	γδ	ADP
dti-2520	134	19	iels	iel	NOUN
dti-2520	134	20	,	,	PUNCT
dti-2520	134	21	induction	induction	NOUN
dti-2520	134	22	of	of	ADP
dti-2520	134	23	mucosal	mucosal	ADJ
dti-2520	134	24	iga	iga	PROPN
dti-2520	134	25	antibodies	antibodie	VERB
dti-2520	134	26	,	,	PUNCT
dti-2520	134	27	and	and	CCONJ
dti-2520	134	28	th17	th17	PROPN
dti-2520	134	29	cells	cell	NOUN
dti-2520	134	30	kalra	kalra	VERB
dti-2520	134	31	et	et	PROPN
dti-2520	134	32	al	al	PROPN
dti-2520	134	33	drug	drug	PROPN
dti-2520	134	34	target	target	NOUN
dti-2520	134	35	insights	insight	NOUN
dti-2520	134	36	2022	2022	NUM
dti-2520	134	37	;	;	PUNCT
dti-2520	134	38	16	16	NUM
dti-2520	134	39	:	:	SYM
dti-2520	134	40	85	85	NUM
dti-2520	134	41	©	©	PROPN
dti-2520	134	42	2022	2022	NUM
dti-2520	134	43	the	the	DET
dti-2520	134	44	authors	author	NOUN
dti-2520	134	45	.	.	PUNCT
dti-2520	135	1	published	publish	VERB
dti-2520	135	2	by	by	ADP
dti-2520	135	3	aboutscience	aboutscience	NOUN
dti-2520	135	4	www.aboutscience.eu	www.aboutscience.eu	NOUN
dti-2520	135	5	(	(	PUNCT
dti-2520	135	6	47	47	NUM
dti-2520	135	7	)	)	PUNCT
dti-2520	135	8	.	.	PUNCT
dti-2520	136	1	these	these	DET
dti-2520	136	2	immune	immune	ADJ
dti-2520	136	3	dysfunctions	dysfunction	NOUN
dti-2520	136	4	are	be	AUX
dti-2520	136	5	restored	restore	VERB
dti-2520	136	6	by	by	ADP
dti-2520	136	7	microbial	microbial	ADJ
dti-2520	136	8	colonization	colonization	NOUN
dti-2520	136	9	,	,	PUNCT
dti-2520	136	10	most	most	ADV
dti-2520	136	11	notably	notably	ADV
dti-2520	136	12	with	with	ADP
dti-2520	136	13	segmented	segment	VERB
dti-2520	136	14	filamentous	filamentous	ADJ
dti-2520	136	15	bacteria	bacteria	NOUN
dti-2520	136	16	and	and	CCONJ
dti-2520	136	17	other	other	ADJ
dti-2520	136	18	commensal	commensal	NOUN
dti-2520	136	19	bacteria	bacteria	NOUN
dti-2520	136	20	.	.	PUNCT
dti-2520	137	1	any	any	DET
dti-2520	137	2	abnormalities	abnormality	NOUN
dti-2520	137	3	that	that	PRON
dti-2520	137	4	lead	lead	VERB
dti-2520	137	5	to	to	PART
dti-2520	137	6	gut	gut	VERB
dti-2520	137	7	dysbiosis	dysbiosis	NOUN
dti-2520	137	8	severely	severely	ADV
dti-2520	137	9	affected	affect	VERB
dti-2520	137	10	the	the	DET
dti-2520	137	11	development	development	NOUN
dti-2520	137	12	of	of	ADP
dti-2520	137	13	intestinal	intestinal	ADJ
dti-2520	137	14	mucosal	mucosal	NOUN
dti-2520	137	15	immunity	immunity	NOUN
dti-2520	137	16	and	and	CCONJ
dti-2520	137	17	make	make	VERB
dti-2520	137	18	individuals	individual	NOUN
dti-2520	137	19	more	more	ADV
dti-2520	137	20	susceptible	susceptible	ADJ
dti-2520	137	21	to	to	ADP
dti-2520	137	22	secondary	secondary	ADJ
dti-2520	137	23	infections	infection	NOUN
dti-2520	137	24	.	.	PUNCT
dti-2520	138	1	a	a	DET
dti-2520	138	2	small	small	ADJ
dti-2520	138	3	animal	animal	NOUN
dti-2520	138	4	study	study	NOUN
dti-2520	138	5	conducted	conduct	VERB
dti-2520	138	6	in	in	ADP
dti-2520	138	7	gf	gf	PROPN
dti-2520	138	8	mice	mouse	NOUN
dti-2520	138	9	showed	show	VERB
dti-2520	138	10	comparatively	comparatively	ADV
dti-2520	138	11	smaller	small	ADJ
dti-2520	138	12	mesenteric	mesenteric	ADJ
dti-2520	138	13	lymph	lymph	NOUN
dti-2520	138	14	nodes	node	NOUN
dti-2520	138	15	,	,	PUNCT
dti-2520	138	16	pp	pp	ADV
dti-2520	138	17	,	,	PUNCT
dti-2520	138	18	and	and	CCONJ
dti-2520	138	19	reduced	reduced	ADJ
dti-2520	138	20	numbers	number	NOUN
dti-2520	138	21	of	of	ADP
dti-2520	138	22	immune	immune	ADJ
dti-2520	138	23	cells	cell	NOUN
dti-2520	138	24	such	such	ADJ
dti-2520	138	25	as	as	ADP
dti-2520	138	26	cd4	cd4	PROPN
dti-2520	138	27	+	+	PROPN
dti-2520	138	28	t	t	NOUN
dti-2520	138	29	cells	cell	NOUN
dti-2520	138	30	,	,	PUNCT
dti-2520	138	31	cd8	cd8	PROPN
dti-2520	138	32	+	+	PROPN
dti-2520	138	33	t	t	NOUN
dti-2520	138	34	cells	cell	NOUN
dti-2520	138	35	,	,	PUNCT
dti-2520	138	36	iga	iga	PROPN
dti-2520	138	37	-	-	PUNCT
dti-2520	138	38	producing	produce	VERB
dti-2520	138	39	plasma	plasma	NOUN
dti-2520	138	40	cells	cell	NOUN
dti-2520	138	41	,	,	PUNCT
dti-2520	138	42	and	and	CCONJ
dti-2520	138	43	intraepithelial	intraepithelial	ADJ
dti-2520	138	44	t	t	PROPN
dti-2520	138	45	-	-	PUNCT
dti-2520	138	46	cell	cell	NOUN
dti-2520	138	47	receptors	receptor	NOUN
dti-2520	138	48	in	in	ADP
dti-2520	138	49	mice	mouse	NOUN
dti-2520	138	50	having	have	VERB
dti-2520	138	51	sepsis	sepsis	NOUN
dti-2520	138	52	as	as	SCONJ
dti-2520	138	53	compared	compare	VERB
dti-2520	138	54	to	to	ADP
dti-2520	138	55	the	the	DET
dti-2520	138	56	control	control	NOUN
dti-2520	138	57	(	(	PUNCT
dti-2520	138	58	14	14	NUM
dti-2520	138	59	)	)	PUNCT
dti-2520	138	60	.	.	PUNCT
dti-2520	139	1	challenges	challenge	NOUN
dti-2520	139	2	,	,	PUNCT
dti-2520	139	3	pitfalls	pitfall	NOUN
dti-2520	139	4	and	and	CCONJ
dti-2520	139	5	future	future	ADJ
dti-2520	139	6	aspects	aspect	NOUN
dti-2520	139	7	in	in	ADP
dti-2520	139	8	immune	immune	ADJ
dti-2520	139	9	microbiome	microbiome	ADJ
dti-2520	139	10	research	research	NOUN
dti-2520	139	11	despite	despite	SCONJ
dti-2520	139	12	the	the	DET
dti-2520	139	13	impressive	impressive	ADJ
dti-2520	139	14	achievement	achievement	NOUN
dti-2520	139	15	that	that	PRON
dti-2520	139	16	has	have	AUX
dti-2520	139	17	greatly	greatly	ADV
dti-2520	139	18	enhanced	enhance	VERB
dti-2520	139	19	our	our	PRON
dti-2520	139	20	understanding	understanding	NOUN
dti-2520	139	21	of	of	ADP
dti-2520	139	22	gut	gut	ADJ
dti-2520	139	23	microbiota	microbiota	NOUN
dti-2520	139	24	diversity	diversity	NOUN
dti-2520	139	25	and	and	CCONJ
dti-2520	139	26	its	its	PRON
dti-2520	139	27	association	association	NOUN
dti-2520	139	28	with	with	ADP
dti-2520	139	29	immune	immune	ADJ
dti-2520	139	30	system	system	NOUN
dti-2520	139	31	development	development	NOUN
dti-2520	139	32	,	,	PUNCT
dti-2520	139	33	many	many	ADJ
dti-2520	139	34	challenges	challenge	NOUN
dti-2520	139	35	remain	remain	VERB
dti-2520	139	36	in	in	ADP
dti-2520	139	37	disentangling	disentangle	VERB
dti-2520	139	38	microbiome	microbiome	ADJ
dti-2520	139	39	-	-	PUNCT
dti-2520	139	40	immune	immune	ADJ
dti-2520	139	41	system	system	NOUN
dti-2520	139	42	interactions	interaction	NOUN
dti-2520	139	43	in	in	ADP
dti-2520	139	44	homeostasis	homeostasis	NOUN
dti-2520	139	45	and	and	CCONJ
dti-2520	139	46	disease	disease	NOUN
dti-2520	139	47	(	(	PUNCT
dti-2520	139	48	50	50	NUM
dti-2520	139	49	)	)	PUNCT
dti-2520	139	50	.	.	PUNCT
dti-2520	140	1	several	several	ADJ
dti-2520	140	2	mechanistic	mechanistic	ADJ
dti-2520	140	3	studies	study	NOUN
dti-2520	140	4	are	be	AUX
dti-2520	140	5	required	require	VERB
dti-2520	140	6	to	to	PART
dti-2520	140	7	explore	explore	VERB
dti-2520	140	8	the	the	DET
dti-2520	140	9	role	role	NOUN
dti-2520	140	10	of	of	ADP
dti-2520	140	11	the	the	DET
dti-2520	140	12	commensal	commensal	ADJ
dti-2520	140	13	microbiome	microbiome	NOUN
dti-2520	140	14	in	in	ADP
dti-2520	140	15	modulating	modulate	VERB
dti-2520	140	16	the	the	DET
dti-2520	140	17	host	host	NOUN
dti-2520	140	18	’s	’s	PART
dti-2520	140	19	innate	innate	ADJ
dti-2520	140	20	and	and	CCONJ
dti-2520	140	21	adaptive	adaptive	ADJ
dti-2520	140	22	immunity	immunity	NOUN
dti-2520	140	23	in	in	ADP
dti-2520	140	24	health	health	NOUN
dti-2520	140	25	and	and	CCONJ
dti-2520	140	26	disease	disease	NOUN
dti-2520	140	27	.	.	PUNCT
dti-2520	141	1	recent	recent	ADJ
dti-2520	141	2	studies	study	NOUN
dti-2520	141	3	conducted	conduct	VERB
dti-2520	141	4	in	in	ADP
dti-2520	141	5	animals	animal	NOUN
dti-2520	141	6	show	show	VERB
dti-2520	141	7	a	a	DET
dti-2520	141	8	bidirectional	bidirectional	ADJ
dti-2520	141	9	relationship	relationship	NOUN
dti-2520	141	10	exists	exist	VERB
dti-2520	141	11	between	between	ADP
dti-2520	141	12	microbiome	microbiome	ADJ
dti-2520	141	13	perturbation	perturbation	NOUN
dti-2520	141	14	and	and	CCONJ
dti-2520	141	15	immune	immune	ADJ
dti-2520	141	16	dysregulation	dysregulation	NOUN
dti-2520	141	17	(	(	PUNCT
dti-2520	141	18	48	48	NUM
dti-2520	141	19	)	)	PUNCT
dti-2520	141	20	.	.	PUNCT
dti-2520	142	1	early	early	ADJ
dti-2520	142	2	-	-	PUNCT
dti-2520	142	3	life	life	NOUN
dti-2520	142	4	colonization	colonization	NOUN
dti-2520	142	5	of	of	ADP
dti-2520	142	6	gut	gut	NOUN
dti-2520	142	7	microbiota	microbiota	NOUN
dti-2520	142	8	and	and	CCONJ
dti-2520	142	9	metabolites	metabolite	NOUN
dti-2520	142	10	causing	cause	VERB
dti-2520	142	11	immune	immune	ADJ
dti-2520	142	12	development	development	NOUN
dti-2520	142	13	,	,	PUNCT
dti-2520	142	14	activation	activation	NOUN
dti-2520	142	15	,	,	PUNCT
dti-2520	142	16	and	and	CCONJ
dti-2520	142	17	chronic	chronic	ADJ
dti-2520	142	18	inflammation	inflammation	NOUN
dti-2520	142	19	conversely	conversely	ADV
dti-2520	142	20	may	may	AUX
dti-2520	142	21	shape	shape	VERB
dti-2520	142	22	the	the	DET
dti-2520	142	23	dysbiotic	dysbiotic	ADJ
dti-2520	142	24	configuration	configuration	NOUN
dti-2520	142	25	and	and	CCONJ
dti-2520	142	26	functions	function	NOUN
dti-2520	142	27	of	of	ADP
dti-2520	142	28	microbial	microbial	ADJ
dti-2520	142	29	communities	community	NOUN
dti-2520	142	30	.	.	PUNCT
dti-2520	143	1	however	however	ADV
dti-2520	143	2	,	,	PUNCT
dti-2520	143	3	a	a	DET
dti-2520	143	4	direct	direct	ADJ
dti-2520	143	5	causal	causal	NOUN
dti-2520	143	6	association	association	NOUN
dti-2520	143	7	between	between	ADP
dti-2520	143	8	the	the	DET
dti-2520	143	9	richness	richness	NOUN
dti-2520	143	10	and	and	CCONJ
dti-2520	143	11	diversity	diversity	NOUN
dti-2520	143	12	of	of	ADP
dti-2520	143	13	gut	gut	ADJ
dti-2520	143	14	microbiota	microbiota	NOUN
dti-2520	143	15	with	with	ADP
dti-2520	143	16	immune	immune	ADJ
dti-2520	143	17	development	development	NOUN
dti-2520	143	18	before	before	ADP
dti-2520	143	19	the	the	DET
dti-2520	143	20	onset	onset	NOUN
dti-2520	143	21	or	or	CCONJ
dti-2520	143	22	during	during	ADP
dti-2520	143	23	the	the	DET
dti-2520	143	24	early	early	ADJ
dti-2520	143	25	stages	stage	NOUN
dti-2520	143	26	of	of	ADP
dti-2520	143	27	the	the	DET
dti-2520	143	28	disease	disease	NOUN
dti-2520	143	29	has	have	AUX
dti-2520	143	30	not	not	PART
dti-2520	143	31	been	be	AUX
dti-2520	143	32	established	establish	VERB
dti-2520	143	33	in	in	ADP
dti-2520	143	34	most	most	ADJ
dti-2520	143	35	medical	medical	ADJ
dti-2520	143	36	conditions	condition	NOUN
dti-2520	143	37	.	.	PUNCT
dti-2520	144	1	in	in	ADP
dti-2520	144	2	the	the	DET
dti-2520	144	3	context	context	NOUN
dti-2520	144	4	of	of	ADP
dti-2520	144	5	septic	septic	ADJ
dti-2520	144	6	patients	patient	NOUN
dti-2520	144	7	,	,	PUNCT
dti-2520	144	8	a	a	DET
dti-2520	144	9	large	large	ADJ
dti-2520	144	10	human	human	ADJ
dti-2520	144	11	study	study	NOUN
dti-2520	144	12	cohort	cohort	NOUN
dti-2520	144	13	is	be	AUX
dti-2520	144	14	required	require	VERB
dti-2520	144	15	to	to	PART
dti-2520	144	16	find	find	VERB
dti-2520	144	17	microbiota	microbiota	NOUN
dti-2520	144	18	composition	composition	NOUN
dti-2520	144	19	,	,	PUNCT
dti-2520	144	20	diversity	diversity	NOUN
dti-2520	144	21	,	,	PUNCT
dti-2520	144	22	and	and	CCONJ
dti-2520	144	23	dysbiotic	dysbiotic	ADJ
dti-2520	144	24	changes	change	NOUN
dti-2520	144	25	before	before	ADV
dti-2520	144	26	,	,	PUNCT
dti-2520	144	27	during	during	ADP
dti-2520	144	28	,	,	PUNCT
dti-2520	144	29	and	and	CCONJ
dti-2520	144	30	after	after	SCONJ
dti-2520	144	31	the	the	DET
dti-2520	144	32	occurrence	occurrence	NOUN
dti-2520	144	33	of	of	ADP
dti-2520	144	34	sepsis	sepsis	NOUN
dti-2520	144	35	to	to	PART
dti-2520	144	36	identify	identify	VERB
dti-2520	144	37	the	the	DET
dti-2520	144	38	protective	protective	ADJ
dti-2520	144	39	commensals	commensal	NOUN
dti-2520	144	40	and	and	CCONJ
dti-2520	144	41	microbiota	microbiota	NOUN
dti-2520	144	42	potentially	potentially	ADV
dti-2520	144	43	associated	associate	VERB
dti-2520	144	44	with	with	ADP
dti-2520	144	45	susceptibility	susceptibility	NOUN
dti-2520	144	46	to	to	ADP
dti-2520	144	47	sepsis	sepsis	NOUN
dti-2520	144	48	and	and	CCONJ
dti-2520	144	49	worse	bad	ADJ
dti-2520	144	50	outcomes	outcome	NOUN
dti-2520	144	51	.	.	PUNCT
dti-2520	145	1	in	in	ADP
dti-2520	145	2	addition	addition	NOUN
dti-2520	145	3	,	,	PUNCT
dti-2520	145	4	a	a	DET
dti-2520	145	5	multidimensional	multidimensional	ADJ
dti-2520	145	6	approach	approach	NOUN
dti-2520	145	7	,	,	PUNCT
dti-2520	145	8	including	include	VERB
dti-2520	145	9	metabolomics	metabolomic	NOUN
dti-2520	145	10	,	,	PUNCT
dti-2520	145	11	proteomics	proteomic	NOUN
dti-2520	145	12	,	,	PUNCT
dti-2520	145	13	single	single	ADJ
dti-2520	145	14	-	-	PUNCT
dti-2520	145	15	cell	cell	NOUN
dti-2520	145	16	transcriptomics	transcriptomic	NOUN
dti-2520	145	17	,	,	PUNCT
dti-2520	145	18	epigenomics	epigenomic	NOUN
dti-2520	145	19	,	,	PUNCT
dti-2520	145	20	and	and	CCONJ
dti-2520	145	21	meta	meta	NOUN
dti-2520	145	22	-	-	PUNCT
dti-2520	145	23	genomics	genomic	NOUN
dti-2520	145	24	,	,	PUNCT
dti-2520	145	25	is	be	AUX
dti-2520	145	26	required	require	VERB
dti-2520	145	27	to	to	PART
dti-2520	145	28	elucidate	elucidate	VERB
dti-2520	145	29	how	how	SCONJ
dti-2520	145	30	the	the	DET
dti-2520	145	31	gut	gut	NOUN
dti-2520	145	32	microbiome	microbiome	ADJ
dti-2520	145	33	and	and	CCONJ
dti-2520	145	34	immune	immune	ADJ
dti-2520	145	35	system	system	NOUN
dti-2520	145	36	are	be	AUX
dti-2520	145	37	cross	cross	ADJ
dti-2520	145	38	-	-	ADJ
dti-2520	145	39	regulated	regulated	ADJ
dti-2520	145	40	during	during	ADP
dti-2520	145	41	sepsis	sepsis	NOUN
dti-2520	145	42	.	.	PUNCT
dti-2520	146	1	finally	finally	ADV
dti-2520	146	2	,	,	PUNCT
dti-2520	146	3	the	the	DET
dti-2520	146	4	microbiome	microbiome	NOUN
dti-2520	146	5	composition	composition	NOUN
dti-2520	146	6	and	and	CCONJ
dti-2520	146	7	immune	immune	ADJ
dti-2520	146	8	responses	response	NOUN
dti-2520	146	9	are	be	AUX
dti-2520	146	10	highly	highly	ADV
dti-2520	146	11	variables	variable	NOUN
dti-2520	146	12	among	among	ADP
dti-2520	146	13	human	human	ADJ
dti-2520	146	14	individuals	individual	NOUN
dti-2520	146	15	and	and	CCONJ
dti-2520	146	16	disease	disease	NOUN
dti-2520	146	17	states	state	NOUN
dti-2520	146	18	.	.	PUNCT
dti-2520	147	1	this	this	DET
dti-2520	147	2	inherent	inherent	ADJ
dti-2520	147	3	interindividual	interindividual	ADJ
dti-2520	147	4	variability	variability	NOUN
dti-2520	147	5	of	of	ADP
dti-2520	147	6	the	the	DET
dti-2520	147	7	gut	gut	NOUN
dti-2520	147	8	microbiome	microbiome	NOUN
dti-2520	147	9	and	and	CCONJ
dti-2520	147	10	associated	associate	VERB
dti-2520	147	11	complexity	complexity	NOUN
dti-2520	147	12	constitutes	constitute	VERB
dti-2520	147	13	a	a	DET
dti-2520	147	14	major	major	ADJ
dti-2520	147	15	experimental	experimental	ADJ
dti-2520	147	16	challenge	challenge	NOUN
dti-2520	147	17	.	.	PUNCT
dti-2520	148	1	this	this	PRON
dti-2520	148	2	increases	increase	VERB
dti-2520	148	3	the	the	DET
dti-2520	148	4	likelihood	likelihood	NOUN
dti-2520	148	5	of	of	ADP
dti-2520	148	6	precision	precision	NOUN
dti-2520	148	7	medicine	medicine	NOUN
dti-2520	148	8	concerning	concern	VERB
dti-2520	148	9	microbiota	microbiota	NOUN
dti-2520	148	10	.	.	PUNCT
dti-2520	149	1	it	it	PRON
dti-2520	149	2	intrigued	intrigue	VERB
dti-2520	149	3	us	we	PRON
dti-2520	149	4	to	to	PART
dti-2520	149	5	predict	predict	VERB
dti-2520	149	6	the	the	DET
dti-2520	149	7	personalized	personalize	VERB
dti-2520	149	8	,	,	PUNCT
dti-2520	149	9	host	host	NOUN
dti-2520	149	10	immune	immune	ADJ
dti-2520	149	11	responses	response	NOUN
dti-2520	149	12	based	base	VERB
dti-2520	149	13	on	on	ADP
dti-2520	149	14	gut	gut	NOUN
dti-2520	149	15	microbiome	microbiome	ADJ
dti-2520	149	16	profiles	profile	NOUN
dti-2520	149	17	in	in	ADP
dti-2520	149	18	terms	term	NOUN
dti-2520	149	19	of	of	ADP
dti-2520	149	20	treatment	treatment	NOUN
dti-2520	149	21	and	and	CCONJ
dti-2520	149	22	prognosis	prognosis	NOUN
dti-2520	149	23	.	.	PUNCT
dti-2520	150	1	therefore	therefore	ADV
dti-2520	150	2	,	,	PUNCT
dti-2520	150	3	the	the	DET
dti-2520	150	4	microbiota	microbiota	NOUN
dti-2520	150	5	is	be	AUX
dti-2520	150	6	a	a	DET
dti-2520	150	7	next	next	ADJ
dti-2520	150	8	-	-	PUNCT
dti-2520	150	9	generation	generation	NOUN
dti-2520	150	10	medicine	medicine	NOUN
dti-2520	150	11	and	and	CCONJ
dti-2520	150	12	may	may	AUX
dti-2520	150	13	facilitate	facilitate	VERB
dti-2520	150	14	the	the	DET
dti-2520	150	15	development	development	NOUN
dti-2520	150	16	of	of	ADP
dti-2520	150	17	personalized	personalized	ADJ
dti-2520	150	18	microbiome	microbiome	NOUN
dti-2520	150	19	-	-	PUNCT
dti-2520	150	20	targeted	target	VERB
dti-2520	150	21	treatments	treatment	NOUN
dti-2520	150	22	for	for	ADP
dti-2520	150	23	immunological	immunological	ADJ
dti-2520	150	24	disease	disease	NOUN
dti-2520	150	25	.	.	PUNCT
dti-2520	151	1	conclusions	conclusion	NOUN
dti-2520	151	2	in	in	ADP
dti-2520	151	3	summary	summary	NOUN
dti-2520	151	4	,	,	PUNCT
dti-2520	151	5	the	the	DET
dti-2520	151	6	intestinal	intestinal	ADJ
dti-2520	151	7	microbiota	microbiota	NOUN
dti-2520	151	8	is	be	AUX
dti-2520	151	9	essentially	essentially	ADV
dti-2520	151	10	required	require	VERB
dti-2520	151	11	for	for	ADP
dti-2520	151	12	the	the	DET
dti-2520	151	13	development	development	NOUN
dti-2520	151	14	and	and	CCONJ
dti-2520	151	15	maturation	maturation	NOUN
dti-2520	151	16	of	of	ADP
dti-2520	151	17	host	host	NOUN
dti-2520	151	18	immunity	immunity	NOUN
dti-2520	151	19	and	and	CCONJ
dti-2520	151	20	contributes	contribute	VERB
dti-2520	151	21	to	to	ADP
dti-2520	151	22	maintaining	maintain	VERB
dti-2520	151	23	intestinal	intestinal	ADJ
dti-2520	151	24	homeostasis	homeostasis	NOUN
dti-2520	151	25	.	.	PUNCT
dti-2520	152	1	recent	recent	ADJ
dti-2520	152	2	studies	study	NOUN
dti-2520	152	3	have	have	AUX
dti-2520	152	4	shown	show	VERB
dti-2520	152	5	the	the	DET
dti-2520	152	6	pivotal	pivotal	ADJ
dti-2520	152	7	role	role	NOUN
dti-2520	152	8	of	of	ADP
dti-2520	152	9	intestinal	intestinal	ADJ
dti-2520	152	10	microbiota	microbiota	NOUN
dti-2520	152	11	in	in	ADP
dti-2520	152	12	modulating	modulate	VERB
dti-2520	152	13	the	the	DET
dti-2520	152	14	host	host	NOUN
dti-2520	152	15	cellular	cellular	ADJ
dti-2520	152	16	immune	immune	ADJ
dti-2520	152	17	response	response	NOUN
dti-2520	152	18	to	to	PART
dti-2520	152	19	stimuli	stimulus	NOUN
dti-2520	152	20	and	and	CCONJ
dti-2520	152	21	enhancing	enhance	VERB
dti-2520	152	22	mucosal	mucosal	ADJ
dti-2520	152	23	immunity	immunity	NOUN
dti-2520	152	24	.	.	PUNCT
dti-2520	153	1	the	the	DET
dti-2520	153	2	mutual	mutual	ADJ
dti-2520	153	3	association	association	NOUN
dti-2520	153	4	between	between	ADP
dti-2520	153	5	the	the	DET
dti-2520	153	6	gut	gut	NOUN
dti-2520	153	7	microbiota	microbiota	NOUN
dti-2520	153	8	and	and	CCONJ
dti-2520	153	9	the	the	DET
dti-2520	153	10	host	host	NOUN
dti-2520	153	11	is	be	AUX
dti-2520	153	12	required	require	VERB
dti-2520	153	13	for	for	ADP
dti-2520	153	14	the	the	DET
dti-2520	153	15	maturation	maturation	NOUN
dti-2520	153	16	and	and	CCONJ
dti-2520	153	17	development	development	NOUN
dti-2520	153	18	of	of	ADP
dti-2520	153	19	host	host	NOUN
dti-2520	153	20	gut	gut	NOUN
dti-2520	153	21	immunity	immunity	NOUN
dti-2520	153	22	.	.	PUNCT
dti-2520	154	1	the	the	DET
dti-2520	154	2	host	host	NOUN
dti-2520	154	3	provides	provide	VERB
dti-2520	154	4	a	a	DET
dti-2520	154	5	suitable	suitable	ADJ
dti-2520	154	6	environment	environment	NOUN
dti-2520	154	7	for	for	ADP
dti-2520	154	8	the	the	DET
dti-2520	154	9	growth	growth	NOUN
dti-2520	154	10	of	of	ADP
dti-2520	154	11	the	the	DET
dti-2520	154	12	microbiome	microbiome	NOUN
dti-2520	154	13	,	,	PUNCT
dti-2520	154	14	and	and	CCONJ
dti-2520	154	15	subsequently	subsequently	ADV
dti-2520	154	16	,	,	PUNCT
dti-2520	154	17	the	the	DET
dti-2520	154	18	gut	gut	NOUN
dti-2520	154	19	microbiota	microbiota	NOUN
dti-2520	154	20	facilitates	facilitate	VERB
dti-2520	154	21	the	the	DET
dti-2520	154	22	development	development	NOUN
dti-2520	154	23	and	and	CCONJ
dti-2520	154	24	maturation	maturation	NOUN
dti-2520	154	25	of	of	ADP
dti-2520	154	26	the	the	DET
dti-2520	154	27	mucosal	mucosal	ADJ
dti-2520	154	28	immune	immune	ADJ
dti-2520	154	29	system	system	NOUN
dti-2520	154	30	.	.	PUNCT
dti-2520	155	1	the	the	DET
dti-2520	155	2	altered	alter	VERB
dti-2520	155	3	composition	composition	NOUN
dti-2520	155	4	and	and	CCONJ
dti-2520	155	5	diversity	diversity	NOUN
dti-2520	155	6	of	of	ADP
dti-2520	155	7	gut	gut	NOUN
dti-2520	155	8	microbiota	microbiota	NOUN
dti-2520	155	9	especially	especially	ADV
dti-2520	155	10	amr	amr	ADJ
dti-2520	155	11	bacteria	bacteria	NOUN
dti-2520	155	12	due	due	ADP
dti-2520	155	13	to	to	ADP
dti-2520	155	14	antibiotics	antibiotic	NOUN
dti-2520	155	15	treatment	treatment	NOUN
dti-2520	155	16	can	can	AUX
dti-2520	155	17	lead	lead	VERB
dti-2520	155	18	to	to	ADP
dti-2520	155	19	the	the	DET
dti-2520	155	20	translocation	translocation	NOUN
dti-2520	155	21	of	of	ADP
dti-2520	155	22	enteric	enteric	ADJ
dti-2520	155	23	bacteria	bacteria	NOUN
dti-2520	155	24	from	from	ADP
dti-2520	155	25	the	the	DET
dti-2520	155	26	gut	gut	NOUN
dti-2520	155	27	to	to	ADP
dti-2520	155	28	the	the	DET
dti-2520	155	29	systemic	systemic	ADJ
dti-2520	155	30	circulation	circulation	NOUN
dti-2520	155	31	and	and	CCONJ
dti-2520	155	32	cause	cause	VERB
dti-2520	155	33	the	the	DET
dti-2520	155	34	pathogenesis	pathogenesis	NOUN
dti-2520	155	35	of	of	ADP
dti-2520	155	36	sepsis	sepsis	NOUN
dti-2520	155	37	.	.	PUNCT
dti-2520	156	1	the	the	DET
dti-2520	156	2	interaction	interaction	NOUN
dti-2520	156	3	between	between	ADP
dti-2520	156	4	the	the	DET
dti-2520	156	5	gut	gut	NOUN
dti-2520	156	6	microbiota	microbiota	NOUN
dti-2520	156	7	and	and	CCONJ
dti-2520	156	8	mucosal	mucosal	ADJ
dti-2520	156	9	immune	immune	ADJ
dti-2520	156	10	system	system	NOUN
dti-2520	156	11	is	be	AUX
dti-2520	156	12	key	key	ADJ
dti-2520	156	13	for	for	ADP
dti-2520	156	14	controlling	control	VERB
dti-2520	156	15	normal	normal	ADJ
dti-2520	156	16	homeostasis	homeostasis	NOUN
dti-2520	156	17	and	and	CCONJ
dti-2520	156	18	inflammatory	inflammatory	ADJ
dti-2520	156	19	response	response	NOUN
dti-2520	156	20	.	.	PUNCT
dti-2520	157	1	impaired	impaired	ADJ
dti-2520	157	2	communication	communication	NOUN
dti-2520	157	3	between	between	ADP
dti-2520	157	4	these	these	DET
dti-2520	157	5	two	two	NUM
dti-2520	157	6	is	be	AUX
dti-2520	157	7	associated	associate	VERB
dti-2520	157	8	with	with	ADP
dti-2520	157	9	the	the	DET
dti-2520	157	10	pathogenesis	pathogenesis	NOUN
dti-2520	157	11	of	of	ADP
dti-2520	157	12	several	several	ADJ
dti-2520	157	13	inflammatory	inflammatory	ADJ
dti-2520	157	14	diseases	disease	NOUN
dti-2520	157	15	and	and	CCONJ
dti-2520	157	16	sepsis	sepsis	NOUN
dti-2520	157	17	,	,	PUNCT
dti-2520	157	18	and	and	CCONJ
dti-2520	157	19	it	it	PRON
dti-2520	157	20	highlights	highlight	VERB
dti-2520	157	21	the	the	DET
dti-2520	157	22	importance	importance	NOUN
dti-2520	157	23	of	of	ADP
dti-2520	157	24	exploring	explore	VERB
dti-2520	157	25	the	the	DET
dti-2520	157	26	function	function	NOUN
dti-2520	157	27	of	of	ADP
dti-2520	157	28	microbiota	microbiota	NOUN
dti-2520	157	29	in	in	ADP
dti-2520	157	30	such	such	ADJ
dti-2520	157	31	diseases	disease	NOUN
dti-2520	157	32	.	.	PUNCT
dti-2520	158	1	disclosures	disclosure	NOUN
dti-2520	158	2	conflict	conflict	NOUN
dti-2520	158	3	of	of	ADP
dti-2520	158	4	interest	interest	NOUN
dti-2520	158	5	:	:	PUNCT
dti-2520	158	6	the	the	DET
dti-2520	158	7	authors	author	NOUN
dti-2520	158	8	declare	declare	VERB
dti-2520	158	9	no	no	DET
dti-2520	158	10	conflict	conflict	NOUN
dti-2520	158	11	of	of	ADP
dti-2520	158	12	interest	interest	NOUN
dti-2520	158	13	.	.	PUNCT
dti-2520	159	1	financial	financial	ADJ
dti-2520	159	2	support	support	NOUN
dti-2520	159	3	:	:	PUNCT
dti-2520	159	4	this	this	DET
dti-2520	159	5	research	research	NOUN
dti-2520	159	6	received	receive	VERB
dti-2520	159	7	no	no	DET
dti-2520	159	8	specific	specific	ADJ
dti-2520	159	9	grant	grant	NOUN
dti-2520	159	10	from	from	ADP
dti-2520	159	11	any	any	DET
dti-2520	159	12	funding	funding	NOUN
dti-2520	159	13	agency	agency	NOUN
dti-2520	159	14	in	in	ADP
dti-2520	159	15	the	the	DET
dti-2520	159	16	public	public	ADJ
dti-2520	159	17	,	,	PUNCT
dti-2520	159	18	commercial	commercial	ADJ
dti-2520	159	19	,	,	PUNCT
dti-2520	159	20	or	or	CCONJ
dti-2520	159	21	not	not	PART
dti-2520	159	22	-	-	PUNCT
dti-2520	159	23	for	for	ADP
dti-2520	159	24	-	-	PUNCT
dti-2520	159	25	profit	profit	NOUN
dti-2520	159	26	sectors	sector	NOUN
dti-2520	159	27	.	.	PUNCT
dti-2520	160	1	authors	author	NOUN
dti-2520	160	2	contribution	contribution	VERB
dti-2520	160	3	:	:	PUNCT
dti-2520	160	4	all	all	DET
dti-2520	160	5	authors	author	NOUN
dti-2520	160	6	contributed	contribute	VERB
dti-2520	160	7	equally	equally	ADV
dti-2520	160	8	to	to	ADP
dti-2520	160	9	this	this	DET
dti-2520	160	10	manuscript	manuscript	NOUN
dti-2520	160	11	.	.	PUNCT
dti-2520	161	1	references	reference	NOUN
dti-2520	161	2	1	1	NUM
dti-2520	161	3	.	.	PUNCT
dti-2520	161	4	bhopale	bhopale	PROPN
dti-2520	161	5	gm	gm	PROPN
dti-2520	161	6	.	.	PUNCT
dti-2520	162	1	antimicrobial	antimicrobial	ADJ
dti-2520	162	2	peptides	peptide	NOUN
dti-2520	162	3	:	:	PUNCT
dti-2520	162	4	a	a	DET
dti-2520	162	5	promising	promising	ADJ
dti-2520	162	6	avenue	avenue	NOUN
dti-2520	162	7	for	for	ADP
dti-2520	162	8	human	human	ADJ
dti-2520	162	9	healthcare	healthcare	PROPN
dti-2520	162	10	.	.	PUNCT
dti-2520	163	1	curr	curr	PROPN
dti-2520	163	2	pharm	pharm	PROPN
dti-2520	163	3	biotechnol	biotechnol	PROPN
dti-2520	163	4	.	.	PUNCT
dti-2520	164	1	2020;21(2	2020;21(2	NUM
dti-2520	164	2	):	):	PUNCT
dti-2520	164	3	90	90	NUM
dti-2520	164	4	-	-	SYM
dti-2520	164	5	96	96	NUM
dti-2520	164	6	.	.	PUNCT
dti-2520	165	1	crossref	crossref	PROPN
dti-2520	165	2	pubmed	pubmed	PROPN
dti-2520	165	3	2	2	NUM
dti-2520	165	4	.	.	PUNCT
dti-2520	166	1	droz	droz	PROPN
dti-2520	166	2	n	n	CCONJ
dti-2520	166	3	,	,	PUNCT
dti-2520	166	4	hsia	hsia	PROPN
dti-2520	166	5	y	y	PROPN
dti-2520	166	6	,	,	PUNCT
dti-2520	166	7	ellis	ellis	PROPN
dti-2520	166	8	s	s	PROPN
dti-2520	166	9	,	,	PUNCT
dti-2520	166	10	dramowski	dramowski	VERB
dti-2520	166	11	a	a	X
dti-2520	166	12	,	,	PUNCT
dti-2520	166	13	sharland	sharland	NOUN
dti-2520	166	14	m	m	PROPN
dti-2520	166	15	,	,	PUNCT
dti-2520	166	16	basmaci	basmaci	PROPN
dti-2520	166	17	r.	r.	PROPN
dti-2520	166	18	bacterial	bacterial	ADJ
dti-2520	166	19	pathogens	pathogen	NOUN
dti-2520	166	20	and	and	CCONJ
dti-2520	166	21	resistance	resistance	NOUN
dti-2520	166	22	causing	cause	VERB
dti-2520	166	23	community	community	NOUN
dti-2520	166	24	acquired	acquire	VERB
dti-2520	166	25	paediatric	paediatric	ADJ
dti-2520	166	26	bloodstream	bloodstream	NOUN
dti-2520	166	27	infections	infection	NOUN
dti-2520	166	28	in	in	ADP
dti-2520	166	29	lowand	lowand	ADJ
dti-2520	166	30	middle	middle	ADJ
dti-2520	166	31	-	-	PUNCT
dti-2520	166	32	income	income	NOUN
dti-2520	166	33	countries	country	NOUN
dti-2520	166	34	:	:	PUNCT
dti-2520	166	35	a	a	DET
dti-2520	166	36	systematic	systematic	ADJ
dti-2520	166	37	review	review	NOUN
dti-2520	166	38	and	and	CCONJ
dti-2520	166	39	meta	meta	ADJ
dti-2520	166	40	-	-	PUNCT
dti-2520	166	41	analysis	analysis	NOUN
dti-2520	166	42	.	.	PUNCT
dti-2520	167	1	antimicrob	antimicrob	PROPN
dti-2520	167	2	resist	resist	VERB
dti-2520	167	3	infect	infect	ADJ
dti-2520	167	4	control	control	NOUN
dti-2520	167	5	.	.	PUNCT
dti-2520	168	1	2019;8(1):207	2019;8(1):207	X
dti-2520	168	2	.	.	PUNCT
dti-2520	169	1	crossref	crossref	PROPN
dti-2520	169	2	pubmed	pubmed	PROPN
dti-2520	169	3	3	3	PROPN
dti-2520	169	4	.	.	PUNCT
dti-2520	169	5	samreen	samreen	VERB
dti-2520	169	6	,	,	PUNCT
dti-2520	169	7	ahmad	ahmad	PROPN
dti-2520	169	8	i	i	PRON
dti-2520	169	9	,	,	PUNCT
dti-2520	169	10	malak	malak	PROPN
dti-2520	169	11	ha	ha	INTJ
dti-2520	169	12	,	,	PUNCT
dti-2520	169	13	abulreesh	abulreesh	ADJ
dti-2520	169	14	hh	hh	PROPN
dti-2520	169	15	.	.	PROPN
dti-2520	169	16	environmental	environmental	ADJ
dti-2520	169	17	antimicrobial	antimicrobial	ADJ
dti-2520	169	18	resistance	resistance	NOUN
dti-2520	169	19	and	and	CCONJ
dti-2520	169	20	its	its	PRON
dti-2520	169	21	drivers	driver	NOUN
dti-2520	169	22	:	:	PUNCT
dti-2520	169	23	a	a	DET
dti-2520	169	24	potential	potential	ADJ
dti-2520	169	25	threat	threat	NOUN
dti-2520	169	26	to	to	ADP
dti-2520	169	27	public	public	ADJ
dti-2520	169	28	health	health	NOUN
dti-2520	169	29	.	.	PUNCT
dti-2520	170	1	j	j	PROPN
dti-2520	170	2	glob	glob	PROPN
dti-2520	170	3	antimicrob	antimicrob	PROPN
dti-2520	170	4	resist	resist	VERB
dti-2520	170	5	.	.	PUNCT
dti-2520	171	1	2021;27:101	2021;27:101	NUM
dti-2520	171	2	-	-	SYM
dti-2520	171	3	111	111	NUM
dti-2520	171	4	.	.	PUNCT
dti-2520	172	1	crossref	crossref	PROPN
dti-2520	172	2	pubmed	pubmed	PROPN
dti-2520	172	3	4	4	PROPN
dti-2520	172	4	.	.	PUNCT
dti-2520	172	5	brinkac	brinkac	PROPN
dti-2520	172	6	l	l	PROPN
dti-2520	172	7	,	,	PUNCT
dti-2520	172	8	voorhies	voorhies	PROPN
dti-2520	172	9	a	a	PROPN
dti-2520	172	10	,	,	PUNCT
dti-2520	172	11	gomez	gomez	PROPN
dti-2520	172	12	a	a	X
dti-2520	172	13	,	,	PUNCT
dti-2520	172	14	nelson	nelson	PROPN
dti-2520	172	15	ke	ke	PROPN
dti-2520	172	16	.	.	PUNCT
dti-2520	173	1	the	the	DET
dti-2520	173	2	threat	threat	NOUN
dti-2520	173	3	of	of	ADP
dti-2520	173	4	antimicrobial	antimicrobial	ADJ
dti-2520	173	5	resistance	resistance	NOUN
dti-2520	173	6	on	on	ADP
dti-2520	173	7	the	the	DET
dti-2520	173	8	human	human	ADJ
dti-2520	173	9	microbiome	microbiome	NOUN
dti-2520	173	10	.	.	PUNCT
dti-2520	174	1	microb	microb	PROPN
dti-2520	174	2	ecol	ecol	PROPN
dti-2520	174	3	.	.	PUNCT
dti-2520	175	1	2017;74(4):1001	2017;74(4):1001	NUM
dti-2520	175	2	-	-	PUNCT
dti-2520	175	3	1008	1008	NUM
dti-2520	175	4	.	.	PUNCT
dti-2520	176	1	crossref	crossref	PROPN
dti-2520	176	2	pubmed	pubmed	PROPN
dti-2520	176	3	5	5	NUM
dti-2520	176	4	.	.	PUNCT
dti-2520	176	5	unemo	unemo	PROPN
dti-2520	176	6	m	m	PROPN
dti-2520	176	7	,	,	PUNCT
dti-2520	176	8	lahra	lahra	NOUN
dti-2520	176	9	mm	mm	PROPN
dti-2520	176	10	,	,	PUNCT
dti-2520	176	11	escher	escher	PROPN
dti-2520	176	12	m	m	PROPN
dti-2520	176	13	,	,	PUNCT
dti-2520	176	14	et	et	PROPN
dti-2520	176	15	al	al	PROPN
dti-2520	176	16	.	.	PROPN
dti-2520	177	1	who	who	PRON
dti-2520	177	2	global	global	ADJ
dti-2520	177	3	antimicrobial	antimicrobial	ADJ
dti-2520	177	4	resistance	resistance	NOUN
dti-2520	177	5	surveillance	surveillance	NOUN
dti-2520	177	6	for	for	ADP
dti-2520	177	7	neisseria	neisseria	NOUN
dti-2520	177	8	gonorrhoeae	gonorrhoeae	PROPN
dti-2520	177	9	2017	2017	NUM
dti-2520	177	10	-	-	SYM
dti-2520	177	11	18	18	NUM
dti-2520	177	12	:	:	PUNCT
dti-2520	177	13	a	a	DET
dti-2520	177	14	retrospective	retrospective	ADJ
dti-2520	177	15	observational	observational	ADJ
dti-2520	177	16	study	study	NOUN
dti-2520	177	17	.	.	PUNCT
dti-2520	178	1	lancet	lancet	PROPN
dti-2520	178	2	microbe	microbe	PROPN
dti-2520	178	3	.	.	PUNCT
dti-2520	179	1	2021;2(11	2021;2(11	NUM
dti-2520	179	2	):	):	PUNCT
dti-2520	180	1	e627	e627	PROPN
dti-2520	180	2	-	-	PUNCT
dti-2520	180	3	e636	e636	PROPN
dti-2520	180	4	.	.	PUNCT
dti-2520	181	1	crossref	crossref	PROPN
dti-2520	181	2	pubmed	pubmed	PROPN
dti-2520	181	3	6	6	NUM
dti-2520	181	4	.	.	PUNCT
dti-2520	182	1	diallo	diallo	PROPN
dti-2520	182	2	oo	oo	PROPN
dti-2520	182	3	,	,	PUNCT
dti-2520	182	4	baron	baron	PROPN
dti-2520	182	5	sa	sa	PROPN
dti-2520	182	6	,	,	PUNCT
dti-2520	182	7	abat	abat	NOUN
dti-2520	182	8	c	c	NOUN
dti-2520	182	9	,	,	PUNCT
dti-2520	182	10	colson	colson	PROPN
dti-2520	182	11	p	p	PROPN
dti-2520	182	12	,	,	PUNCT
dti-2520	182	13	chaudet	chaudet	NOUN
dti-2520	182	14	h	h	NOUN
dti-2520	182	15	,	,	PUNCT
dti-2520	182	16	rolain	rolain	PROPN
dti-2520	183	1	jm	jm	PROPN
dti-2520	183	2	.	.	PROPN
dti-2520	183	3	antibiotic	antibiotic	ADJ
dti-2520	183	4	resistance	resistance	NOUN
dti-2520	183	5	surveillance	surveillance	NOUN
dti-2520	183	6	systems	system	NOUN
dti-2520	183	7	:	:	PUNCT
dti-2520	183	8	a	a	DET
dti-2520	183	9	review	review	NOUN
dti-2520	183	10	.	.	PUNCT
dti-2520	184	1	j	j	PROPN
dti-2520	184	2	glob	glob	PROPN
dti-2520	184	3	antimicrob	antimicrob	PROPN
dti-2520	184	4	resist	resist	VERB
dti-2520	184	5	.	.	PUNCT
dti-2520	185	1	2020;23:430	2020;23:430	NUM
dti-2520	185	2	-	-	PUNCT
dti-2520	185	3	438	438	NUM
dti-2520	185	4	.	.	PUNCT
dti-2520	186	1	crossref	crossref	PROPN
dti-2520	186	2	pubmed	pubmed	PROPN
dti-2520	186	3	7	7	PROPN
dti-2520	186	4	.	.	PUNCT
dti-2520	187	1	naylor	naylor	PROPN
dti-2520	187	2	nr	nr	PROPN
dti-2520	187	3	,	,	PUNCT
dti-2520	187	4	atun	atun	PROPN
dti-2520	187	5	r	r	PROPN
dti-2520	187	6	,	,	PUNCT
dti-2520	187	7	zhu	zhu	PROPN
dti-2520	187	8	n	n	CCONJ
dti-2520	187	9	,	,	PUNCT
dti-2520	187	10	et	et	PROPN
dti-2520	187	11	al	al	PROPN
dti-2520	187	12	.	.	PUNCT
dti-2520	187	13	estimating	estimate	VERB
dti-2520	187	14	the	the	DET
dti-2520	187	15	burden	burden	NOUN
dti-2520	187	16	of	of	ADP
dti-2520	187	17	antimicrobial	antimicrobial	ADJ
dti-2520	187	18	resistance	resistance	NOUN
dti-2520	187	19	:	:	PUNCT
dti-2520	187	20	a	a	DET
dti-2520	187	21	systematic	systematic	ADJ
dti-2520	187	22	literature	literature	NOUN
dti-2520	187	23	review	review	NOUN
dti-2520	187	24	.	.	PUNCT
dti-2520	188	1	antimicrob	antimicrob	PROPN
dti-2520	188	2	resist	resist	VERB
dti-2520	188	3	infect	infect	ADJ
dti-2520	188	4	control	control	NOUN
dti-2520	188	5	.	.	PUNCT
dti-2520	189	1	2018;7(1):58	2018;7(1):58	NUM
dti-2520	189	2	.	.	PUNCT
dti-2520	189	3	crossref	crossref	PROPN
dti-2520	189	4	pubmed	pubmed	PROPN
dti-2520	189	5	8	8	PROPN
dti-2520	189	6	.	.	PUNCT
dti-2520	190	1	paladino	paladino	PROPN
dti-2520	190	2	ja	ja	PROPN
dti-2520	190	3	,	,	PUNCT
dti-2520	190	4	sunderlin	sunderlin	PROPN
dti-2520	190	5	jl	jl	PROPN
dti-2520	190	6	,	,	PUNCT
dti-2520	190	7	price	price	NOUN
dti-2520	190	8	cs	cs	PROPN
dti-2520	190	9	,	,	PUNCT
dti-2520	190	10	schentag	schentag	ADJ
dti-2520	190	11	jj	jj	PROPN
dti-2520	190	12	.	.	PUNCT
dti-2520	191	1	economic	economic	ADJ
dti-2520	191	2	consequences	consequence	NOUN
dti-2520	191	3	of	of	ADP
dti-2520	191	4	antimicrobial	antimicrobial	ADJ
dti-2520	191	5	resistance	resistance	NOUN
dti-2520	191	6	.	.	PUNCT
dti-2520	192	1	surg	surg	PROPN
dti-2520	192	2	infect	infect	PROPN
dti-2520	192	3	(	(	PUNCT
dti-2520	192	4	larchmt	larchmt	PROPN
dti-2520	192	5	)	)	PUNCT
dti-2520	192	6	.	.	PUNCT
dti-2520	193	1	2002;3(3):259	2002;3(3):259	X
dti-2520	193	2	-	-	SYM
dti-2520	193	3	267	267	NUM
dti-2520	193	4	.	.	PUNCT
dti-2520	194	1	crossref	crossref	PROPN
dti-2520	194	2	pubmed	pubmed	PROPN
dti-2520	194	3	9	9	PROPN
dti-2520	194	4	.	.	PUNCT
dti-2520	195	1	murray	murray	PROPN
dti-2520	195	2	cjl	cjl	PROPN
dti-2520	195	3	,	,	PUNCT
dti-2520	195	4	ikuta	ikuta	PROPN
dti-2520	195	5	ks	ks	PROPN
dti-2520	195	6	,	,	PUNCT
dti-2520	195	7	sharara	sharara	NOUN
dti-2520	195	8	f	f	X
dti-2520	195	9	,	,	PUNCT
dti-2520	195	10	et	et	PROPN
dti-2520	195	11	al	al	PROPN
dti-2520	195	12	;	;	PUNCT
dti-2520	195	13	antimicrobial	antimicrobial	ADJ
dti-2520	195	14	resistance	resistance	NOUN
dti-2520	195	15	collaborators	collaborator	NOUN
dti-2520	195	16	.	.	PUNCT
dti-2520	196	1	global	global	ADJ
dti-2520	196	2	burden	burden	NOUN
dti-2520	196	3	of	of	ADP
dti-2520	196	4	bacterial	bacterial	ADJ
dti-2520	196	5	antimicrobial	antimicrobial	ADJ
dti-2520	196	6	resistance	resistance	NOUN
dti-2520	196	7	in	in	ADP
dti-2520	196	8	2019	2019	NUM
dti-2520	196	9	:	:	PUNCT
dti-2520	196	10	a	a	DET
dti-2520	196	11	systematic	systematic	ADJ
dti-2520	196	12	analysis	analysis	NOUN
dti-2520	196	13	.	.	PUNCT
dti-2520	197	1	lancet	lancet	NOUN
dti-2520	197	2	.	.	PUNCT
dti-2520	198	1	2022;399(10325):629	2022;399(10325):629	NUM
dti-2520	198	2	-	-	SYM
dti-2520	198	3	655	655	NUM
dti-2520	198	4	.	.	PUNCT
dti-2520	199	1	crossref	crossref	PROPN
dti-2520	199	2	pubmed	pubmed	PROPN
dti-2520	199	3	https://doi.org/10.2174/1389201020666191011121722	https://doi.org/10.2174/1389201020666191011121722	NUM
dti-2520	199	4	https://www.ncbi.nlm.nih.gov/pubmed/31612826	https://www.ncbi.nlm.nih.gov/pubmed/31612826	NUM
dti-2520	199	5	https://doi.org/10.1186/s13756-019-0673-5	https://doi.org/10.1186/s13756-019-0673-5	NUM
dti-2520	199	6	https://www.ncbi.nlm.nih.gov/pubmed/31893041	https://www.ncbi.nlm.nih.gov/pubmed/31893041	NUM
dti-2520	199	7	https://doi.org/10.1016/j.jgar.2021.08.001	https://doi.org/10.1016/j.jgar.2021.08.001	NOUN
dti-2520	199	8	https://www.ncbi.nlm.nih.gov/pubmed/34454098	https://www.ncbi.nlm.nih.gov/pubmed/34454098	NUM
dti-2520	199	9	https://doi.org/10.1007/s00248-017-0985-z	https://doi.org/10.1007/s00248-017-0985-z	PROPN
dti-2520	199	10	https://www.ncbi.nlm.nih.gov/pubmed/28492988	https://www.ncbi.nlm.nih.gov/pubmed/28492988	X
dti-2520	199	11	https://doi.org/10.1016/s2666-5247(21)00171-3	https://doi.org/10.1016/s2666-5247(21)00171-3	PROPN
dti-2520	199	12	https://www.ncbi.nlm.nih.gov/pubmed/35544082	https://www.ncbi.nlm.nih.gov/pubmed/35544082	NUM
dti-2520	199	13	https://doi.org/10.1016/j.jgar.2020.10.009	https://doi.org/10.1016/j.jgar.2020.10.009	NOUN
dti-2520	199	14	https://www.ncbi.nlm.nih.gov/pubmed/33176216	https://www.ncbi.nlm.nih.gov/pubmed/33176216	NUM
dti-2520	199	15	https://doi.org/10.1186/s13756-018-0336-y	https://doi.org/10.1186/s13756-018-0336-y	PROPN
dti-2520	199	16	https://www.ncbi.nlm.nih.gov/pubmed/29713465	https://www.ncbi.nlm.nih.gov/pubmed/29713465	NUM
dti-2520	199	17	https://doi.org/10.1089/109629602761624225	https://doi.org/10.1089/109629602761624225	PRON
dti-2520	199	18	https://www.ncbi.nlm.nih.gov/pubmed/12542927	https://www.ncbi.nlm.nih.gov/pubmed/12542927	NUM
dti-2520	199	19	https://doi.org/10.1016/s0140-6736(21)02724-0	https://doi.org/10.1016/s0140-6736(21)02724-0	NOUN
dti-2520	199	20	https://www.ncbi.nlm.nih.gov/pubmed/35065702	https://www.ncbi.nlm.nih.gov/pubmed/35065702	NUM
dti-2520	199	21	gut	gut	NOUN
dti-2520	199	22	microbiota	microbiota	NOUN
dti-2520	199	23	and	and	CCONJ
dti-2520	199	24	sepsis86	sepsis86	NOUN
dti-2520	200	1	©	©	PROPN
dti-2520	200	2	2022	2022	NUM
dti-2520	201	1	the	the	DET
dti-2520	201	2	authors	author	NOUN
dti-2520	201	3	.	.	PUNCT
dti-2520	202	1	drug	drug	NOUN
dti-2520	202	2	target	target	NOUN
dti-2520	202	3	insights	insight	NOUN
dti-2520	202	4	issn	issn	VERB
dti-2520	202	5	1177	1177	NUM
dti-2520	202	6	-	-	SYM
dti-2520	202	7	3928	3928	NUM
dti-2520	202	8	www.aboutscience.eu/dti	www.aboutscience.eu/dti	VERB
dti-2520	202	9	10	10	NUM
dti-2520	202	10	.	.	PUNCT
dti-2520	203	1	bhardwaj	bhardwaj	PROPN
dti-2520	203	2	n	n	CCONJ
dti-2520	203	3	,	,	PUNCT
dti-2520	203	4	mathur	mathur	PROPN
dti-2520	203	5	p	p	PROPN
dti-2520	203	6	,	,	PUNCT
dti-2520	203	7	behera	behera	PROPN
dti-2520	203	8	b	b	PROPN
dti-2520	203	9	,	,	PUNCT
dti-2520	203	10	mathur	mathur	PROPN
dti-2520	203	11	k	k	PROPN
dti-2520	203	12	,	,	PUNCT
dti-2520	203	13	kapil	kapil	PROPN
dti-2520	203	14	a	a	PROPN
dti-2520	203	15	,	,	PUNCT
dti-2520	203	16	misra	misra	PROPN
dti-2520	203	17	mc	mc	PROPN
dti-2520	203	18	.	.	PROPN
dti-2520	203	19	antimicrobial	antimicrobial	ADJ
dti-2520	203	20	resistance	resistance	NOUN
dti-2520	203	21	in	in	ADP
dti-2520	203	22	beta	beta	NOUN
dti-2520	203	23	-	-	PUNCT
dti-2520	203	24	haemolytic	haemolytic	ADJ
dti-2520	203	25	streptococci	streptococci	NOUN
dti-2520	203	26	in	in	ADP
dti-2520	203	27	india	india	PROPN
dti-2520	203	28	:	:	PUNCT
dti-2520	203	29	a	a	DET
dti-2520	203	30	four	four	NUM
dti-2520	203	31	-	-	PUNCT
dti-2520	203	32	year	year	NOUN
dti-2520	203	33	study	study	NOUN
dti-2520	203	34	.	.	PUNCT
dti-2520	204	1	indian	indian	PROPN
dti-2520	204	2	j	j	PROPN
dti-2520	204	3	med	med	PROPN
dti-2520	204	4	res	re	NOUN
dti-2520	204	5	.	.	PUNCT
dti-2520	205	1	2018;147(1	2018;147(1	NUM
dti-2520	205	2	):	):	PUNCT
dti-2520	205	3	81	81	NUM
dti-2520	205	4	-	-	SYM
dti-2520	205	5	87	87	NUM
dti-2520	205	6	.	.	PUNCT
dti-2520	206	1	crossref	crossref	PROPN
dti-2520	206	2	pubmed	pubmed	PROPN
dti-2520	206	3	11	11	NUM
dti-2520	206	4	.	.	PUNCT
dti-2520	207	1	veeraraghavan	veeraraghavan	PROPN
dti-2520	207	2	b	b	PROPN
dti-2520	207	3	,	,	PUNCT
dti-2520	207	4	walia	walia	PROPN
dti-2520	207	5	k.	k.	PROPN
dti-2520	207	6	antimicrobial	antimicrobial	PROPN
dti-2520	207	7	susceptibility	susceptibility	NOUN
dti-2520	207	8	profile	profile	PROPN
dti-2520	207	9	&	&	CCONJ
dti-2520	207	10	resistance	resistance	NOUN
dti-2520	207	11	mechanisms	mechanism	NOUN
dti-2520	207	12	of	of	ADP
dti-2520	207	13	global	global	ADJ
dti-2520	207	14	antimicrobial	antimicrobial	ADJ
dti-2520	207	15	resistance	resistance	NOUN
dti-2520	207	16	surveillance	surveillance	NOUN
dti-2520	207	17	system	system	NOUN
dti-2520	207	18	(	(	PUNCT
dti-2520	207	19	glass	glass	NOUN
dti-2520	207	20	)	)	PUNCT
dti-2520	207	21	priority	priority	NOUN
dti-2520	207	22	pathogens	pathogen	NOUN
dti-2520	207	23	from	from	ADP
dti-2520	207	24	india	india	PROPN
dti-2520	207	25	.	.	PUNCT
dti-2520	208	1	indian	indian	PROPN
dti-2520	208	2	j	j	PROPN
dti-2520	208	3	med	med	PROPN
dti-2520	208	4	res	re	NOUN
dti-2520	208	5	.	.	PUNCT
dti-2520	209	1	2019;149(2):87	2019;149(2):87	NUM
dti-2520	209	2	-	-	SYM
dti-2520	209	3	96	96	NUM
dti-2520	209	4	.	.	PUNCT
dti-2520	210	1	crossref	crossref	PROPN
dti-2520	210	2	pubmed	pubmed	PROPN
dti-2520	210	3	12	12	NUM
dti-2520	210	4	.	.	PUNCT
dti-2520	211	1	broom	broom	PROPN
dti-2520	211	2	a	a	PRON
dti-2520	211	3	,	,	PUNCT
dti-2520	211	4	doron	doron	PROPN
dti-2520	211	5	a.	a.	PROPN
dti-2520	211	6	antimicrobial	antimicrobial	PROPN
dti-2520	211	7	resistance	resistance	NOUN
dti-2520	211	8	,	,	PUNCT
dti-2520	211	9	politics	politic	NOUN
dti-2520	211	10	,	,	PUNCT
dti-2520	211	11	and	and	CCONJ
dti-2520	211	12	practice	practice	NOUN
dti-2520	211	13	in	in	ADP
dti-2520	211	14	india	india	PROPN
dti-2520	211	15	.	.	PUNCT
dti-2520	212	1	qual	qual	PROPN
dti-2520	212	2	health	health	PROPN
dti-2520	212	3	res	re	NOUN
dti-2520	212	4	.	.	PUNCT
dti-2520	213	1	2020;30(11):1684	2020;30(11):1684	NUM
dti-2520	213	2	-	-	SYM
dti-2520	213	3	1696	1696	NUM
dti-2520	213	4	.	.	PUNCT
dti-2520	214	1	crossref	crossref	PROPN
dti-2520	214	2	pubmed	pubmed	PROPN
dti-2520	214	3	13	13	NUM
dti-2520	214	4	.	.	PUNCT
dti-2520	215	1	ramachandran	ramachandran	PROPN
dti-2520	215	2	r	r	PROPN
dti-2520	215	3	,	,	PUNCT
dti-2520	215	4	muniyandi	muniyandi	ADJ
dti-2520	215	5	m.	m.	NOUN
dti-2520	215	6	rapid	rapid	ADJ
dti-2520	215	7	molecular	molecular	ADJ
dti-2520	215	8	diagnostics	diagnostic	NOUN
dti-2520	215	9	for	for	ADP
dti-2520	215	10	multi	multi	ADJ
dti-2520	215	11	-	-	ADJ
dti-2520	215	12	drug	drug	ADJ
dti-2520	215	13	resistant	resistant	ADJ
dti-2520	215	14	tuberculosis	tuberculosis	NOUN
dti-2520	215	15	in	in	ADP
dti-2520	215	16	india	india	PROPN
dti-2520	215	17	.	.	PUNCT
dti-2520	216	1	expert	expert	PROPN
dti-2520	216	2	rev	rev	VERB
dti-2520	216	3	anti	anti	PROPN
dti-2520	216	4	infect	infect	PROPN
dti-2520	216	5	ther	ther	ADV
dti-2520	216	6	.	.	PUNCT
dti-2520	217	1	2018;16(3):197	2018;16(3):197	NUM
dti-2520	217	2	-	-	SYM
dti-2520	217	3	204	204	NUM
dti-2520	217	4	.	.	PUNCT
dti-2520	218	1	crossref	crossref	PROPN
dti-2520	218	2	pubmed	pubmed	PROPN
dti-2520	218	3	14	14	PROPN
dti-2520	218	4	.	.	PUNCT
dti-2520	219	1	stoll	stoll	PROPN
dti-2520	219	2	bj	bj	PROPN
dti-2520	219	3	,	,	PUNCT
dti-2520	219	4	puopolo	puopolo	PROPN
dti-2520	219	5	km	km	PROPN
dti-2520	219	6	,	,	PUNCT
dti-2520	219	7	hansen	hansen	PROPN
dti-2520	219	8	ni	ni	PROPN
dti-2520	219	9	,	,	PUNCT
dti-2520	219	10	et	et	PROPN
dti-2520	219	11	al	al	PROPN
dti-2520	219	12	;	;	PUNCT
dti-2520	219	13	eunice	eunice	PROPN
dti-2520	219	14	kennedy	kennedy	PROPN
dti-2520	219	15	shriver	shriver	PROPN
dti-2520	219	16	national	national	PROPN
dti-2520	219	17	institute	institute	PROPN
dti-2520	219	18	of	of	ADP
dti-2520	219	19	child	child	PROPN
dti-2520	219	20	health	health	PROPN
dti-2520	219	21	and	and	CCONJ
dti-2520	219	22	human	human	ADJ
dti-2520	219	23	development	development	NOUN
dti-2520	219	24	neonatal	neonatal	ADJ
dti-2520	219	25	research	research	NOUN
dti-2520	219	26	network	network	NOUN
dti-2520	219	27	.	.	PUNCT
dti-2520	220	1	early	early	ADJ
dti-2520	220	2	-	-	PUNCT
dti-2520	220	3	onset	onset	NOUN
dti-2520	220	4	neonatal	neonatal	ADJ
dti-2520	220	5	sepsis	sepsis	NOUN
dti-2520	220	6	2015	2015	NUM
dti-2520	220	7	to	to	ADP
dti-2520	220	8	2017	2017	NUM
dti-2520	220	9	,	,	PUNCT
dti-2520	220	10	the	the	DET
dti-2520	220	11	rise	rise	NOUN
dti-2520	220	12	of	of	ADP
dti-2520	220	13	escherichia	escherichia	NOUN
dti-2520	220	14	coli	coli	NOUN
dti-2520	220	15	,	,	PUNCT
dti-2520	220	16	and	and	CCONJ
dti-2520	220	17	the	the	DET
dti-2520	220	18	need	need	NOUN
dti-2520	220	19	for	for	ADP
dti-2520	220	20	novel	novel	ADJ
dti-2520	220	21	prevention	prevention	NOUN
dti-2520	220	22	strategies	strategy	NOUN
dti-2520	220	23	.	.	PUNCT
dti-2520	221	1	jama	jama	PROPN
dti-2520	221	2	pediatr	pediatr	PROPN
dti-2520	221	3	.	.	PUNCT
dti-2520	222	1	2020;174(7):e200593	2020;174(7):e200593	NUM
dti-2520	222	2	.	.	PUNCT
dti-2520	222	3	crossref	crossref	PROPN
dti-2520	222	4	pubmed	pubmed	PROPN
dti-2520	222	5	15	15	PROPN
dti-2520	222	6	.	.	PUNCT
dti-2520	223	1	mutua	mutua	PROPN
dti-2520	223	2	f	f	PROPN
dti-2520	223	3	,	,	PUNCT
dti-2520	223	4	sharma	sharma	PROPN
dti-2520	223	5	g	g	PROPN
dti-2520	223	6	,	,	PUNCT
dti-2520	223	7	grace	grace	NOUN
dti-2520	223	8	d	d	NOUN
dti-2520	223	9	,	,	PUNCT
dti-2520	223	10	bandyopadhyay	bandyopadhyay	NOUN
dti-2520	223	11	s	s	PART
dti-2520	223	12	,	,	PUNCT
dti-2520	223	13	shome	shome	PROPN
dti-2520	223	14	b	b	NUM
dti-2520	223	15	,	,	PUNCT
dti-2520	223	16	lindahl	lindahl	PROPN
dti-2520	223	17	j.	j.	PROPN
dti-2520	224	1	a	a	DET
dti-2520	224	2	review	review	NOUN
dti-2520	224	3	of	of	ADP
dti-2520	224	4	animal	animal	NOUN
dti-2520	224	5	health	health	NOUN
dti-2520	224	6	and	and	CCONJ
dti-2520	224	7	drug	drug	NOUN
dti-2520	224	8	use	use	NOUN
dti-2520	224	9	practices	practice	NOUN
dti-2520	224	10	in	in	ADP
dti-2520	224	11	india	india	PROPN
dti-2520	224	12	,	,	PUNCT
dti-2520	224	13	and	and	CCONJ
dti-2520	224	14	their	their	PRON
dti-2520	224	15	possible	possible	ADJ
dti-2520	224	16	link	link	NOUN
dti-2520	224	17	to	to	ADP
dti-2520	224	18	antimicrobial	antimicrobial	ADJ
dti-2520	224	19	resistance	resistance	NOUN
dti-2520	224	20	.	.	PUNCT
dti-2520	225	1	antimicrob	antimicrob	PROPN
dti-2520	225	2	resist	resist	VERB
dti-2520	225	3	infect	infect	ADJ
dti-2520	225	4	control	control	NOUN
dti-2520	225	5	.	.	PUNCT
dti-2520	226	1	2020;9(1):103	2020;9(1):103	X
dti-2520	226	2	.	.	PUNCT
dti-2520	226	3	crossref	crossref	PROPN
dti-2520	226	4	pubmed	pubmed	PROPN
dti-2520	226	5	16	16	NUM
dti-2520	226	6	.	.	PUNCT
dti-2520	227	1	verma	verma	PROPN
dti-2520	227	2	a	a	PROPN
dti-2520	227	3	,	,	PUNCT
dti-2520	227	4	sahay	sahay	PROPN
dti-2520	227	5	s.	s.	PROPN
dti-2520	227	6	healthcare	healthcare	PROPN
dti-2520	227	7	needs	need	NOUN
dti-2520	227	8	and	and	CCONJ
dti-2520	227	9	programmatic	programmatic	ADJ
dti-2520	227	10	gaps	gap	NOUN
dti-2520	227	11	in	in	ADP
dti-2520	227	12	transition	transition	NOUN
dti-2520	227	13	from	from	ADP
dti-2520	227	14	pediatric	pediatric	ADJ
dti-2520	227	15	to	to	ADP
dti-2520	227	16	adult	adult	NOUN
dti-2520	227	17	care	care	NOUN
dti-2520	227	18	of	of	ADP
dti-2520	227	19	vertically	vertically	ADV
dti-2520	227	20	transmitted	transmit	VERB
dti-2520	227	21	hiv	hiv	PROPN
dti-2520	227	22	infected	infect	VERB
dti-2520	227	23	adolescents	adolescent	NOUN
dti-2520	227	24	in	in	ADP
dti-2520	227	25	india	india	PROPN
dti-2520	227	26	.	.	PUNCT
dti-2520	228	1	plos	plos	PROPN
dti-2520	228	2	one	one	NUM
dti-2520	228	3	.	.	PUNCT
dti-2520	229	1	2019;14(10):e022	2019;14(10):e022	NUM
dti-2520	229	2	4490	4490	NUM
dti-2520	229	3	.	.	PUNCT
dti-2520	230	1	crossref	crossref	PROPN
dti-2520	230	2	pubmed	pubmed	PROPN
dti-2520	230	3	17	17	NUM
dti-2520	230	4	.	.	PUNCT
dti-2520	231	1	adelman	adelman	PROPN
dti-2520	231	2	mw	mw	PROPN
dti-2520	231	3	,	,	PUNCT
dti-2520	231	4	woodworth	woodworth	PROPN
dti-2520	231	5	mh	mh	PROPN
dti-2520	231	6	,	,	PUNCT
dti-2520	231	7	langelier	langelier	NOUN
dti-2520	231	8	c	c	NOUN
dti-2520	231	9	,	,	PUNCT
dti-2520	231	10	et	et	PROPN
dti-2520	231	11	al	al	PROPN
dti-2520	231	12	.	.	PUNCT
dti-2520	232	1	the	the	DET
dti-2520	232	2	gut	gut	NOUN
dti-2520	232	3	microbiome	microbiome	NOUN
dti-2520	232	4	’s	’s	PART
dti-2520	232	5	role	role	NOUN
dti-2520	232	6	in	in	ADP
dti-2520	232	7	the	the	DET
dti-2520	232	8	development	development	NOUN
dti-2520	232	9	,	,	PUNCT
dti-2520	232	10	maintenance	maintenance	NOUN
dti-2520	232	11	,	,	PUNCT
dti-2520	232	12	and	and	CCONJ
dti-2520	232	13	outcomes	outcome	NOUN
dti-2520	232	14	of	of	ADP
dti-2520	232	15	sepsis	sepsis	NOUN
dti-2520	232	16	.	.	PUNCT
dti-2520	233	1	crit	crit	PROPN
dti-2520	233	2	care	care	NOUN
dti-2520	233	3	.	.	PUNCT
dti-2520	234	1	2020;24(1):278	2020;24(1):278	NUM
dti-2520	234	2	.	.	PUNCT
dti-2520	235	1	crossref	crossref	PROPN
dti-2520	235	2	pubmed	pubmed	PROPN
dti-2520	235	3	18	18	NUM
dti-2520	235	4	.	.	PUNCT
dti-2520	235	5	scheithauer	scheithauer	PROPN
dti-2520	235	6	tpm	tpm	PROPN
dti-2520	235	7	,	,	PUNCT
dti-2520	235	8	rampanelli	rampanelli	NOUN
dti-2520	235	9	e	e	NOUN
dti-2520	235	10	,	,	PUNCT
dti-2520	235	11	nieuwdorp	nieuwdorp	PROPN
dti-2520	235	12	m	m	PROPN
dti-2520	235	13	,	,	PUNCT
dti-2520	235	14	et	et	PROPN
dti-2520	235	15	al	al	PROPN
dti-2520	235	16	.	.	PUNCT
dti-2520	236	1	gut	gut	NOUN
dti-2520	236	2	microbiota	microbiota	NOUN
dti-2520	236	3	as	as	ADP
dti-2520	236	4	a	a	DET
dti-2520	236	5	trigger	trigger	NOUN
dti-2520	236	6	for	for	ADP
dti-2520	236	7	metabolic	metabolic	ADJ
dti-2520	236	8	inflammation	inflammation	NOUN
dti-2520	236	9	in	in	ADP
dti-2520	236	10	obesity	obesity	NOUN
dti-2520	236	11	and	and	CCONJ
dti-2520	236	12	type	type	NOUN
dti-2520	236	13	2	2	NUM
dti-2520	236	14	diabetes	diabetes	NOUN
dti-2520	236	15	.	.	PUNCT
dti-2520	237	1	front	front	ADJ
dti-2520	237	2	immunol	immunol	NOUN
dti-2520	237	3	.	.	PUNCT
dti-2520	238	1	2020;11:571731	2020;11:571731	NUM
dti-2520	238	2	.	.	PUNCT
dti-2520	238	3	crossref	crossref	PROPN
dti-2520	238	4	pubmed	pubmed	PROPN
dti-2520	238	5	19	19	NUM
dti-2520	238	6	.	.	PUNCT
dti-2520	239	1	chen	chen	PROPN
dti-2520	239	2	y	y	PROPN
dti-2520	239	3	,	,	PUNCT
dti-2520	239	4	zhou	zhou	PROPN
dti-2520	239	5	j	j	PROPN
dti-2520	239	6	,	,	PUNCT
dti-2520	239	7	wang	wang	PROPN
dti-2520	239	8	l.	l.	PROPN
dti-2520	239	9	role	role	PROPN
dti-2520	239	10	and	and	CCONJ
dti-2520	239	11	mechanism	mechanism	NOUN
dti-2520	239	12	of	of	ADP
dti-2520	239	13	gut	gut	NOUN
dti-2520	239	14	microbiota	microbiota	NOUN
dti-2520	239	15	in	in	ADP
dti-2520	239	16	human	human	ADJ
dti-2520	239	17	disease	disease	NOUN
dti-2520	239	18	.	.	PUNCT
dti-2520	240	1	front	front	ADJ
dti-2520	240	2	cell	cell	NOUN
dti-2520	240	3	infect	infect	VERB
dti-2520	240	4	microbiol	microbiol	NOUN
dti-2520	240	5	.	.	PUNCT
dti-2520	241	1	2021;11:625913	2021;11:625913	X
dti-2520	241	2	.	.	PUNCT
dti-2520	241	3	crossref	crossref	PROPN
dti-2520	241	4	pubmed	pubmed	PROPN
dti-2520	241	5	20	20	PROPN
dti-2520	241	6	.	.	PUNCT
dti-2520	242	1	haak	haak	PROPN
dti-2520	242	2	bw	bw	PROPN
dti-2520	242	3	,	,	PUNCT
dti-2520	242	4	wiersinga	wiersinga	ADV
dti-2520	242	5	wj	wj	NOUN
dti-2520	242	6	.	.	PUNCT
dti-2520	243	1	the	the	DET
dti-2520	243	2	role	role	NOUN
dti-2520	243	3	of	of	ADP
dti-2520	243	4	the	the	DET
dti-2520	243	5	gut	gut	NOUN
dti-2520	243	6	microbiota	microbiota	NOUN
dti-2520	243	7	in	in	ADP
dti-2520	243	8	sepsis	sepsis	NOUN
dti-2520	243	9	.	.	PUNCT
dti-2520	244	1	lancet	lancet	PROPN
dti-2520	244	2	gastroenterol	gastroenterol	PROPN
dti-2520	244	3	hepatol	hepatol	ADV
dti-2520	244	4	.	.	PUNCT
dti-2520	245	1	2017;2(2):135	2017;2(2):135	X
dti-2520	245	2	-	-	SYM
dti-2520	245	3	143	143	NUM
dti-2520	245	4	.	.	PUNCT
dti-2520	246	1	crossref	crossref	PROPN
dti-2520	246	2	pubmed	pubmed	PROPN
dti-2520	246	3	21	21	NUM
dti-2520	246	4	.	.	PUNCT
dti-2520	247	1	adak	adak	PROPN
dti-2520	247	2	a	a	PROPN
dti-2520	247	3	,	,	PUNCT
dti-2520	247	4	khan	khan	PROPN
dti-2520	247	5	mr	mr	PROPN
dti-2520	247	6	.	.	PROPN
dti-2520	247	7	an	an	DET
dti-2520	247	8	insight	insight	NOUN
dti-2520	247	9	into	into	ADP
dti-2520	247	10	gut	gut	NOUN
dti-2520	247	11	microbiota	microbiota	NOUN
dti-2520	247	12	and	and	CCONJ
dti-2520	247	13	its	its	PRON
dti-2520	247	14	functionalities	functionality	NOUN
dti-2520	247	15	.	.	PUNCT
dti-2520	248	1	cell	cell	NOUN
dti-2520	248	2	mol	mol	ADP
dti-2520	248	3	life	life	PROPN
dti-2520	248	4	sci	sci	PROPN
dti-2520	248	5	.	.	PUNCT
dti-2520	249	1	2019;76(3):473	2019;76(3):473	NUM
dti-2520	249	2	-	-	SYM
dti-2520	249	3	493	493	NUM
dti-2520	249	4	.	.	PUNCT
dti-2520	250	1	crossref	crossref	PROPN
dti-2520	250	2	pubmed	pubmed	PROPN
dti-2520	250	3	22	22	NUM
dti-2520	250	4	.	.	PUNCT
dti-2520	251	1	hills	hills	PROPN
dti-2520	251	2	rd	rd	PROPN
dti-2520	251	3	jr	jr	PROPN
dti-2520	251	4	,	,	PUNCT
dti-2520	251	5	pontefract	pontefract	PROPN
dti-2520	251	6	ba	ba	PROPN
dti-2520	251	7	,	,	PUNCT
dti-2520	251	8	mishcon	mishcon	PROPN
dti-2520	251	9	hr	hr	PROPN
dti-2520	251	10	,	,	PUNCT
dti-2520	251	11	black	black	ADJ
dti-2520	251	12	ca	ca	NOUN
dti-2520	251	13	,	,	PUNCT
dti-2520	251	14	sutton	sutton	PROPN
dti-2520	251	15	sc	sc	PROPN
dti-2520	251	16	,	,	PUNCT
dti-2520	251	17	theberge	theberge	NOUN
dti-2520	251	18	cr	cr	PROPN
dti-2520	251	19	.	.	PUNCT
dti-2520	252	1	gut	gut	PROPN
dti-2520	252	2	microbiome	microbiome	NOUN
dti-2520	252	3	:	:	PUNCT
dti-2520	252	4	profound	profound	ADJ
dti-2520	252	5	implications	implication	NOUN
dti-2520	252	6	for	for	ADP
dti-2520	252	7	diet	diet	NOUN
dti-2520	252	8	and	and	CCONJ
dti-2520	252	9	disease	disease	NOUN
dti-2520	252	10	.	.	PUNCT
dti-2520	253	1	nutrients	nutrient	NOUN
dti-2520	253	2	.	.	PUNCT
dti-2520	254	1	2019;11(7):e1613	2019;11(7):e1613	NUM
dti-2520	254	2	.	.	PUNCT
dti-2520	254	3	crossref	crossref	PROPN
dti-2520	254	4	pubmed	pubmed	PROPN
dti-2520	254	5	23	23	NUM
dti-2520	254	6	.	.	PUNCT
dti-2520	255	1	sakkas	sakkas	PROPN
dti-2520	255	2	h	h	PROPN
dti-2520	255	3	,	,	PUNCT
dti-2520	255	4	bozidis	bozidis	X
dti-2520	255	5	p	p	NOUN
dti-2520	255	6	,	,	PUNCT
dti-2520	255	7	touzios	touzio	NOUN
dti-2520	255	8	c	c	NOUN
dti-2520	255	9	,	,	PUNCT
dti-2520	255	10	et	et	PROPN
dti-2520	255	11	al	al	PROPN
dti-2520	255	12	.	.	PUNCT
dti-2520	255	13	nutritional	nutritional	ADJ
dti-2520	255	14	status	status	NOUN
dti-2520	255	15	and	and	CCONJ
dti-2520	255	16	the	the	DET
dti-2520	255	17	influence	influence	NOUN
dti-2520	255	18	of	of	ADP
dti-2520	255	19	the	the	DET
dti-2520	255	20	vegan	vegan	NOUN
dti-2520	255	21	diet	diet	NOUN
dti-2520	255	22	on	on	ADP
dti-2520	255	23	the	the	DET
dti-2520	255	24	gut	gut	NOUN
dti-2520	255	25	microbiota	microbiota	NOUN
dti-2520	255	26	and	and	CCONJ
dti-2520	255	27	human	human	ADJ
dti-2520	255	28	health	health	NOUN
dti-2520	255	29	.	.	PUNCT
dti-2520	256	1	medicina	medicina	PROPN
dti-2520	256	2	(	(	PUNCT
dti-2520	256	3	kaunas	kaunas	PROPN
dti-2520	256	4	)	)	PUNCT
dti-2520	256	5	.	.	PUNCT
dti-2520	257	1	2020;56(2):88	2020;56(2):88	X
dti-2520	257	2	.	.	PUNCT
dti-2520	258	1	crossref	crossref	PROPN
dti-2520	258	2	pubmed	pubmed	PROPN
dti-2520	258	3	24	24	NUM
dti-2520	258	4	.	.	PUNCT
dti-2520	259	1	amoroso	amoroso	PROPN
dti-2520	259	2	c	c	PROPN
dti-2520	259	3	,	,	PUNCT
dti-2520	259	4	perillo	perillo	PROPN
dti-2520	259	5	f	f	PROPN
dti-2520	259	6	,	,	PUNCT
dti-2520	259	7	strati	strati	PROPN
dti-2520	259	8	f	f	PROPN
dti-2520	259	9	,	,	PUNCT
dti-2520	259	10	fantini	fantini	PROPN
dti-2520	259	11	mc	mc	PROPN
dti-2520	259	12	,	,	PUNCT
dti-2520	259	13	caprioli	caprioli	PROPN
dti-2520	259	14	f	f	PROPN
dti-2520	259	15	,	,	PUNCT
dti-2520	259	16	facciotti	facciotti	PROPN
dti-2520	259	17	f.	f.	PROPN
dti-2520	259	18	the	the	DET
dti-2520	259	19	role	role	NOUN
dti-2520	259	20	of	of	ADP
dti-2520	259	21	gut	gut	ADJ
dti-2520	259	22	microbiota	microbiota	NOUN
dti-2520	259	23	biomodulators	biomodulator	NOUN
dti-2520	259	24	on	on	ADP
dti-2520	259	25	mucosal	mucosal	NOUN
dti-2520	259	26	immunity	immunity	NOUN
dti-2520	259	27	and	and	CCONJ
dti-2520	259	28	intestinal	intestinal	ADJ
dti-2520	259	29	inflammation	inflammation	NOUN
dti-2520	259	30	.	.	PUNCT
dti-2520	260	1	cells	cell	NOUN
dti-2520	260	2	.	.	PUNCT
dti-2520	261	1	2020;9(5):e1234	2020;9(5):e1234	NUM
dti-2520	261	2	.	.	PUNCT
dti-2520	262	1	crossref	crossref	PROPN
dti-2520	262	2	pubmed	pubmed	PROPN
dti-2520	262	3	25	25	NUM
dti-2520	262	4	.	.	PUNCT
dti-2520	263	1	gomaa	gomaa	PROPN
dti-2520	263	2	ez	ez	PROPN
dti-2520	263	3	.	.	PROPN
dti-2520	263	4	human	human	ADJ
dti-2520	263	5	gut	gut	NOUN
dti-2520	263	6	microbiota	microbiota	NOUN
dti-2520	263	7	/	/	SYM
dti-2520	263	8	microbiome	microbiome	NOUN
dti-2520	263	9	in	in	ADP
dti-2520	263	10	health	health	NOUN
dti-2520	263	11	and	and	CCONJ
dti-2520	263	12	diseases	disease	NOUN
dti-2520	263	13	:	:	PUNCT
dti-2520	263	14	a	a	DET
dti-2520	263	15	review	review	NOUN
dti-2520	263	16	.	.	PUNCT
dti-2520	264	1	antonie	antonie	PROPN
dti-2520	264	2	van	van	PROPN
dti-2520	264	3	leeuwenhoek	leeuwenhoek	PROPN
dti-2520	264	4	.	.	PUNCT
dti-2520	265	1	2020;113(12):20192040	2020;113(12):20192040	NUM
dti-2520	265	2	.	.	X
dti-2520	265	3	crossref	crossref	PROPN
dti-2520	265	4	pubmed	pubmed	PROPN
dti-2520	265	5	26	26	NUM
dti-2520	265	6	.	.	PUNCT
dti-2520	266	1	leclercq	leclercq	PROPN
dti-2520	266	2	s	s	PROPN
dti-2520	266	3	,	,	PUNCT
dti-2520	266	4	matamoros	matamoros	PROPN
dti-2520	266	5	s	s	PROPN
dti-2520	266	6	,	,	PUNCT
dti-2520	266	7	cani	cani	PROPN
dti-2520	266	8	pd	pd	PROPN
dti-2520	266	9	,	,	PUNCT
dti-2520	266	10	et	et	PROPN
dti-2520	266	11	al	al	PROPN
dti-2520	266	12	.	.	PUNCT
dti-2520	267	1	intestinal	intestinal	ADJ
dti-2520	267	2	permeability	permeability	NOUN
dti-2520	267	3	,	,	PUNCT
dti-2520	267	4	gut	gut	NOUN
dti-2520	267	5	-	-	PUNCT
dti-2520	267	6	bacterial	bacterial	ADJ
dti-2520	267	7	dysbiosis	dysbiosis	NOUN
dti-2520	267	8	,	,	PUNCT
dti-2520	267	9	and	and	CCONJ
dti-2520	267	10	behavioral	behavioral	ADJ
dti-2520	267	11	markers	marker	NOUN
dti-2520	267	12	of	of	ADP
dti-2520	267	13	alcoholdependence	alcoholdependence	NOUN
dti-2520	267	14	severity	severity	NOUN
dti-2520	267	15	.	.	PUNCT
dti-2520	268	1	proc	proc	PROPN
dti-2520	268	2	natl	natl	PROPN
dti-2520	268	3	acad	acad	PROPN
dti-2520	268	4	sci	sci	PROPN
dti-2520	268	5	usa	usa	PROPN
dti-2520	268	6	.	.	PROPN
dti-2520	268	7	2014;111(42	2014;111(42	PROPN
dti-2520	268	8	):	):	PUNCT
dti-2520	268	9	e4485	e4485	PROPN
dti-2520	268	10	-	-	PUNCT
dti-2520	268	11	e4493	e4493	PROPN
dti-2520	268	12	.	.	PUNCT
dti-2520	269	1	crossref	crossref	PROPN
dti-2520	269	2	pubmed	pubmed	PROPN
dti-2520	269	3	27	27	NUM
dti-2520	269	4	.	.	PUNCT
dti-2520	270	1	marizzoni	marizzoni	VERB
dti-2520	270	2	m	m	PROPN
dti-2520	270	3	,	,	PUNCT
dti-2520	270	4	cattaneo	cattaneo	VERB
dti-2520	270	5	a	a	PRON
dti-2520	270	6	,	,	PUNCT
dti-2520	270	7	mirabelli	mirabelli	NOUN
dti-2520	270	8	p	p	NOUN
dti-2520	270	9	,	,	PUNCT
dti-2520	270	10	et	et	PROPN
dti-2520	270	11	al	al	PROPN
dti-2520	270	12	.	.	PUNCT
dti-2520	270	13	short	short	ADJ
dti-2520	270	14	-	-	PUNCT
dti-2520	270	15	chain	chain	NOUN
dti-2520	270	16	fatty	fatty	NOUN
dti-2520	270	17	acids	acid	NOUN
dti-2520	270	18	and	and	CCONJ
dti-2520	270	19	lipopolysaccharide	lipopolysaccharide	ADV
dti-2520	270	20	as	as	ADP
dti-2520	270	21	mediators	mediator	NOUN
dti-2520	270	22	between	between	ADP
dti-2520	270	23	gut	gut	NOUN
dti-2520	270	24	dysbiosis	dysbiosis	NOUN
dti-2520	270	25	and	and	CCONJ
dti-2520	270	26	amyloid	amyloid	NOUN
dti-2520	270	27	pathology	pathology	NOUN
dti-2520	270	28	in	in	ADP
dti-2520	270	29	alzheimer	alzheimer	PROPN
dti-2520	270	30	’s	’s	PART
dti-2520	270	31	disease	disease	NOUN
dti-2520	270	32	.	.	PUNCT
dti-2520	271	1	j	j	PROPN
dti-2520	271	2	alzheimers	alzheimers	PROPN
dti-2520	271	3	dis	dis	PROPN
dti-2520	271	4	.	.	PUNCT
dti-2520	272	1	2020;78(2):683	2020;78(2):683	X
dti-2520	272	2	-	-	SYM
dti-2520	272	3	697	697	NUM
dti-2520	272	4	.	.	PUNCT
dti-2520	273	1	crossref	crossref	PROPN
dti-2520	273	2	pubmed	pubmed	PROPN
dti-2520	273	3	28	28	PROPN
dti-2520	273	4	.	.	PUNCT
dti-2520	274	1	dinan	dinan	PROPN
dti-2520	274	2	tg	tg	PROPN
dti-2520	274	3	,	,	PUNCT
dti-2520	274	4	cryan	cryan	PROPN
dti-2520	274	5	jf	jf	PROPN
dti-2520	274	6	.	.	PUNCT
dti-2520	275	1	the	the	DET
dti-2520	275	2	microbiome	microbiome	ADJ
dti-2520	275	3	-	-	PUNCT
dti-2520	275	4	gut	gut	NOUN
dti-2520	275	5	-	-	PUNCT
dti-2520	275	6	brain	brain	NOUN
dti-2520	275	7	axis	axis	NOUN
dti-2520	275	8	in	in	ADP
dti-2520	275	9	health	health	NOUN
dti-2520	275	10	and	and	CCONJ
dti-2520	275	11	disease	disease	NOUN
dti-2520	275	12	.	.	PUNCT
dti-2520	276	1	gastroenterol	gastroenterol	PROPN
dti-2520	276	2	clin	clin	PROPN
dti-2520	276	3	north	north	PROPN
dti-2520	276	4	am	am	PROPN
dti-2520	276	5	.	.	PUNCT
dti-2520	277	1	2017;46(1):77	2017;46(1):77	X
dti-2520	277	2	-	-	SYM
dti-2520	277	3	89	89	NUM
dti-2520	277	4	.	.	PUNCT
dti-2520	278	1	crossref	crossref	PROPN
dti-2520	278	2	pubmed	pubmed	PROPN
dti-2520	278	3	29	29	NUM
dti-2520	278	4	.	.	PUNCT
dti-2520	279	1	fleischmann	fleischmann	PROPN
dti-2520	279	2	c	c	PROPN
dti-2520	279	3	,	,	PUNCT
dti-2520	279	4	scherag	scherag	NOUN
dti-2520	279	5	a	a	NOUN
dti-2520	279	6	,	,	PUNCT
dti-2520	279	7	adhikari	adhikari	PROPN
dti-2520	279	8	nkj	nkj	PROPN
dti-2520	279	9	,	,	PUNCT
dti-2520	279	10	et	et	PROPN
dti-2520	279	11	al	al	PROPN
dti-2520	279	12	;	;	PUNCT
dti-2520	279	13	international	international	ADJ
dti-2520	279	14	forum	forum	PROPN
dti-2520	279	15	of	of	ADP
dti-2520	279	16	acute	acute	PROPN
dti-2520	279	17	care	care	NOUN
dti-2520	279	18	trialists	trialist	NOUN
dti-2520	279	19	.	.	PUNCT
dti-2520	280	1	assessment	assessment	NOUN
dti-2520	280	2	of	of	ADP
dti-2520	280	3	global	global	ADJ
dti-2520	280	4	incidence	incidence	NOUN
dti-2520	280	5	and	and	CCONJ
dti-2520	280	6	mortality	mortality	NOUN
dti-2520	280	7	of	of	ADP
dti-2520	280	8	hospital	hospital	NOUN
dti-2520	280	9	-	-	PUNCT
dti-2520	280	10	treated	treat	VERB
dti-2520	280	11	sepsis	sepsis	NOUN
dti-2520	280	12	.	.	PUNCT
dti-2520	281	1	current	current	ADJ
dti-2520	281	2	estimates	estimate	NOUN
dti-2520	281	3	and	and	CCONJ
dti-2520	281	4	limitations	limitation	NOUN
dti-2520	281	5	.	.	PUNCT
dti-2520	282	1	am	be	AUX
dti-2520	282	2	j	j	PROPN
dti-2520	282	3	respir	respir	NOUN
dti-2520	282	4	crit	crit	PROPN
dti-2520	282	5	care	care	NOUN
dti-2520	282	6	med	me	VERB
dti-2520	282	7	.	.	PUNCT
dti-2520	283	1	2016;193(3	2016;193(3	NUM
dti-2520	283	2	):	):	PUNCT
dti-2520	283	3	259	259	NUM
dti-2520	283	4	-	-	SYM
dti-2520	283	5	272	272	NUM
dti-2520	283	6	.	.	PUNCT
dti-2520	284	1	crossref	crossref	PROPN
dti-2520	284	2	pubmed	pubmed	PROPN
dti-2520	284	3	30	30	PROPN
dti-2520	284	4	.	.	PUNCT
dti-2520	285	1	rhee	rhee	PROPN
dti-2520	285	2	c	c	PROPN
dti-2520	285	3	,	,	PUNCT
dti-2520	285	4	jones	jones	PROPN
dti-2520	285	5	tm	tm	PROPN
dti-2520	285	6	,	,	PUNCT
dti-2520	285	7	hamad	hamad	PROPN
dti-2520	285	8	y	y	PROPN
dti-2520	285	9	,	,	PUNCT
dti-2520	285	10	et	et	PROPN
dti-2520	285	11	al	al	PROPN
dti-2520	285	12	;	;	PUNCT
dti-2520	285	13	centers	center	NOUN
dti-2520	285	14	for	for	ADP
dti-2520	285	15	disease	disease	NOUN
dti-2520	285	16	control	control	NOUN
dti-2520	285	17	and	and	CCONJ
dti-2520	285	18	prevention	prevention	NOUN
dti-2520	285	19	(	(	PUNCT
dti-2520	285	20	cdc	cdc	PROPN
dti-2520	285	21	)	)	PUNCT
dti-2520	285	22	prevention	prevention	NOUN
dti-2520	285	23	epicenters	epicenter	NOUN
dti-2520	285	24	program	program	NOUN
dti-2520	285	25	.	.	PUNCT
dti-2520	286	1	prevalence	prevalence	NOUN
dti-2520	286	2	,	,	PUNCT
dti-2520	286	3	underlying	underlie	VERB
dti-2520	286	4	causes	cause	NOUN
dti-2520	286	5	,	,	PUNCT
dti-2520	286	6	and	and	CCONJ
dti-2520	286	7	preventability	preventability	NOUN
dti-2520	286	8	of	of	ADP
dti-2520	286	9	sepsisassociated	sepsisassociate	VERB
dti-2520	286	10	mortality	mortality	NOUN
dti-2520	286	11	in	in	ADP
dti-2520	286	12	us	us	PROPN
dti-2520	286	13	acute	acute	PROPN
dti-2520	286	14	care	care	NOUN
dti-2520	286	15	hospitals	hospital	NOUN
dti-2520	286	16	.	.	PUNCT
dti-2520	287	1	jama	jama	PROPN
dti-2520	287	2	netw	netw	PROPN
dti-2520	287	3	open	open	ADJ
dti-2520	287	4	.	.	PUNCT
dti-2520	288	1	2019;2(2):e187571	2019;2(2):e187571	X
dti-2520	288	2	.	.	PUNCT
dti-2520	289	1	crossref	crossref	PROPN
dti-2520	289	2	pubmed	pubmed	PROPN
dti-2520	289	3	31	31	NUM
dti-2520	289	4	.	.	PUNCT
dti-2520	290	1	rossaint	rossaint	PROPN
dti-2520	290	2	j	j	PROPN
dti-2520	290	3	,	,	PUNCT
dti-2520	290	4	zarbock	zarbock	NOUN
dti-2520	290	5	a.	a.	NOUN
dti-2520	290	6	pathogenesis	pathogenesis	NOUN
dti-2520	290	7	of	of	ADP
dti-2520	290	8	multiple	multiple	ADJ
dti-2520	290	9	organ	organ	NOUN
dti-2520	290	10	failure	failure	NOUN
dti-2520	290	11	in	in	ADP
dti-2520	290	12	sepsis	sepsis	NOUN
dti-2520	290	13	.	.	PUNCT
dti-2520	291	1	crit	crit	PROPN
dti-2520	291	2	rev	rev	PROPN
dti-2520	291	3	immunol	immunol	NOUN
dti-2520	291	4	.	.	PUNCT
dti-2520	292	1	2015;35(4):277	2015;35(4):277	NOUN
dti-2520	292	2	-	-	PUNCT
dti-2520	292	3	291	291	NUM
dti-2520	292	4	.	.	PUNCT
dti-2520	293	1	crossref	crossref	PROPN
dti-2520	293	2	pubmed	pubmed	PROPN
dti-2520	293	3	32	32	NUM
dti-2520	293	4	.	.	PUNCT
dti-2520	294	1	gupta	gupta	PROPN
dti-2520	294	2	dl	dl	PROPN
dti-2520	294	3	,	,	PUNCT
dti-2520	294	4	bhoi	bhoi	NOUN
dti-2520	294	5	s	s	PROPN
dti-2520	294	6	,	,	PUNCT
dti-2520	294	7	mohan	mohan	PROPN
dti-2520	294	8	t	t	PROPN
dti-2520	294	9	,	,	PUNCT
dti-2520	294	10	galwnkar	galwnkar	NOUN
dti-2520	294	11	s	s	PROPN
dti-2520	294	12	,	,	PUNCT
dti-2520	294	13	rao	rao	PROPN
dti-2520	294	14	dn	dn	PROPN
dti-2520	294	15	.	.	PROPN
dti-2520	294	16	coexistence	coexistence	NOUN
dti-2520	294	17	of	of	ADP
dti-2520	294	18	th1	th1	PROPN
dti-2520	294	19	/	/	SYM
dti-2520	294	20	th2	th2	PROPN
dti-2520	294	21	and	and	CCONJ
dti-2520	294	22	th17	th17	PROPN
dti-2520	294	23	/	/	SYM
dti-2520	294	24	treg	treg	PROPN
dti-2520	294	25	imbalances	imbalance	NOUN
dti-2520	294	26	in	in	ADP
dti-2520	294	27	patients	patient	NOUN
dti-2520	294	28	with	with	ADP
dti-2520	294	29	post	post	NOUN
dti-2520	294	30	traumatic	traumatic	ADJ
dti-2520	294	31	sepsis	sepsis	NOUN
dti-2520	294	32	.	.	PUNCT
dti-2520	295	1	cytokine	cytokine	NOUN
dti-2520	295	2	.	.	PUNCT
dti-2520	296	1	2016;88:214	2016;88:214	X
dti-2520	296	2	-	-	PUNCT
dti-2520	296	3	221	221	NUM
dti-2520	296	4	.	.	PUNCT
dti-2520	297	1	crossref	crossref	PROPN
dti-2520	297	2	pubmed	pubmed	PROPN
dti-2520	297	3	33	33	NUM
dti-2520	297	4	.	.	PUNCT
dti-2520	298	1	gupta	gupta	PROPN
dti-2520	298	2	dl	dl	PROPN
dti-2520	298	3	,	,	PUNCT
dti-2520	298	4	sharma	sharma	PROPN
dti-2520	298	5	a	a	PROPN
dti-2520	298	6	,	,	PUNCT
dti-2520	298	7	soni	soni	PROPN
dti-2520	298	8	kd	kd	PROPN
dti-2520	298	9	,	,	PUNCT
dti-2520	298	10	kazim	kazim	PROPN
dti-2520	298	11	sn	sn	PROPN
dti-2520	298	12	,	,	PUNCT
dti-2520	298	13	bhoi	bhoi	PROPN
dti-2520	298	14	s	s	PROPN
dti-2520	298	15	,	,	PUNCT
dti-2520	298	16	rao	rao	PROPN
dti-2520	298	17	dn	dn	PROPN
dti-2520	298	18	.	.	PROPN
dti-2520	298	19	changes	change	NOUN
dti-2520	298	20	in	in	ADP
dti-2520	298	21	the	the	DET
dti-2520	298	22	behaviour	behaviour	NOUN
dti-2520	298	23	of	of	ADP
dti-2520	298	24	monocyte	monocyte	NOUN
dti-2520	298	25	subsets	subset	NOUN
dti-2520	298	26	in	in	ADP
dti-2520	298	27	acute	acute	ADJ
dti-2520	298	28	posttraumatic	posttraumatic	ADJ
dti-2520	298	29	sepsis	sepsis	NOUN
dti-2520	298	30	patients	patient	NOUN
dti-2520	298	31	.	.	PUNCT
dti-2520	299	1	mol	mol	ADP
dti-2520	299	2	immunol	immunol	NOUN
dti-2520	299	3	.	.	PUNCT
dti-2520	299	4	2021;136:65	2021;136:65	NUM
dti-2520	299	5	-	-	SYM
dti-2520	299	6	72	72	NUM
dti-2520	299	7	.	.	PUNCT
dti-2520	300	1	crossref	crossref	PROPN
dti-2520	300	2	pubmed	pubmed	PROPN
dti-2520	300	3	34	34	NUM
dti-2520	300	4	.	.	PUNCT
dti-2520	301	1	chen	chen	PROPN
dti-2520	301	2	r	r	PROPN
dti-2520	301	3	,	,	PUNCT
dti-2520	301	4	wang	wang	PROPN
dti-2520	301	5	j	j	PROPN
dti-2520	301	6	,	,	PUNCT
dti-2520	301	7	zhan	zhan	PROPN
dti-2520	301	8	r	r	PROPN
dti-2520	301	9	,	,	PUNCT
dti-2520	301	10	zhang	zhang	PROPN
dti-2520	301	11	l	l	PROPN
dti-2520	301	12	,	,	PUNCT
dti-2520	301	13	wang	wang	PROPN
dti-2520	301	14	x.	x.	PROPN
dti-2520	301	15	fecal	fecal	ADJ
dti-2520	301	16	metabonomics	metabonomic	NOUN
dti-2520	301	17	combined	combine	VERB
dti-2520	301	18	with	with	ADP
dti-2520	301	19	16s	16s	PROPN
dti-2520	301	20	rrna	rrna	PROPN
dti-2520	301	21	gene	gene	NOUN
dti-2520	301	22	sequencing	sequence	VERB
dti-2520	301	23	to	to	PART
dti-2520	301	24	analyze	analyze	VERB
dti-2520	301	25	the	the	DET
dti-2520	301	26	changes	change	NOUN
dti-2520	301	27	of	of	ADP
dti-2520	301	28	gut	gut	NOUN
dti-2520	301	29	microbiota	microbiota	NOUN
dti-2520	301	30	in	in	ADP
dti-2520	301	31	rats	rat	NOUN
dti-2520	301	32	with	with	ADP
dti-2520	301	33	kidney	kidney	NOUN
dti-2520	301	34	-	-	PUNCT
dti-2520	301	35	yang	yang	PROPN
dti-2520	301	36	deficiency	deficiency	NOUN
dti-2520	301	37	syndrome	syndrome	NOUN
dti-2520	301	38	and	and	CCONJ
dti-2520	301	39	the	the	DET
dti-2520	301	40	intervention	intervention	ADJ
dti-2520	301	41	effect	effect	NOUN
dti-2520	301	42	of	of	ADP
dti-2520	301	43	you	you	NOUN
dti-2520	301	44	-	-	PUNCT
dti-2520	301	45	gui	gui	NOUN
dti-2520	301	46	pill	pill	NOUN
dti-2520	301	47	.	.	PUNCT
dti-2520	302	1	j	j	PROPN
dti-2520	302	2	ethnopharmacol	ethnopharmacol	PROPN
dti-2520	302	3	.	.	PUNCT
dti-2520	303	1	2019;244:112139	2019;244:112139	NUM
dti-2520	303	2	.	.	PUNCT
dti-2520	304	1	crossref	crossref	PROPN
dti-2520	304	2	pubmed	pubmed	PROPN
dti-2520	304	3	35	35	NUM
dti-2520	304	4	.	.	PUNCT
dti-2520	305	1	zhou	zhou	PROPN
dti-2520	305	2	x	x	PROPN
dti-2520	305	3	,	,	PUNCT
dti-2520	305	4	li	li	PROPN
dti-2520	305	5	j	j	PROPN
dti-2520	305	6	,	,	PUNCT
dti-2520	305	7	guo	guo	PROPN
dti-2520	305	8	j	j	PROPN
dti-2520	305	9	,	,	PUNCT
dti-2520	305	10	et	et	PROPN
dti-2520	305	11	al	al	PROPN
dti-2520	305	12	.	.	PUNCT
dti-2520	306	1	gut	gut	NOUN
dti-2520	306	2	-	-	PUNCT
dti-2520	306	3	dependent	dependent	ADJ
dti-2520	306	4	microbial	microbial	ADJ
dti-2520	306	5	translocation	translocation	NOUN
dti-2520	306	6	induces	induce	VERB
dti-2520	306	7	inflammation	inflammation	NOUN
dti-2520	306	8	and	and	CCONJ
dti-2520	306	9	cardiovascular	cardiovascular	ADJ
dti-2520	306	10	events	event	NOUN
dti-2520	306	11	after	after	ADP
dti-2520	306	12	st	st	NOUN
dti-2520	306	13	-	-	PUNCT
dti-2520	306	14	elevation	elevation	NOUN
dti-2520	306	15	myocardial	myocardial	ADJ
dti-2520	306	16	infarction	infarction	NOUN
dti-2520	306	17	.	.	PUNCT
dti-2520	307	1	microbiome	microbiome	NOUN
dti-2520	307	2	.	.	PUNCT
dti-2520	308	1	2018;6(1):66	2018;6(1):66	NUM
dti-2520	308	2	.	.	PUNCT
dti-2520	309	1	crossref	crossref	PROPN
dti-2520	309	2	pubmed	pubmed	PROPN
dti-2520	309	3	36	36	NUM
dti-2520	309	4	.	.	PUNCT
dti-2520	310	1	becattini	becattini	PROPN
dti-2520	310	2	s	s	PROPN
dti-2520	310	3	,	,	PUNCT
dti-2520	310	4	taur	taur	PROPN
dti-2520	310	5	y	y	PROPN
dti-2520	310	6	,	,	PUNCT
dti-2520	310	7	pamer	pamer	NOUN
dti-2520	310	8	eg	eg	NOUN
dti-2520	310	9	.	.	PUNCT
dti-2520	311	1	antibiotic	antibiotic	ADJ
dti-2520	311	2	-	-	PUNCT
dti-2520	311	3	induced	induce	VERB
dti-2520	311	4	changes	change	NOUN
dti-2520	311	5	in	in	ADP
dti-2520	311	6	the	the	DET
dti-2520	311	7	intestinal	intestinal	ADJ
dti-2520	311	8	microbiota	microbiota	NOUN
dti-2520	311	9	and	and	CCONJ
dti-2520	311	10	disease	disease	NOUN
dti-2520	311	11	.	.	PUNCT
dti-2520	312	1	trends	trend	NOUN
dti-2520	312	2	mol	mol	ADP
dti-2520	312	3	med	med	PROPN
dti-2520	312	4	.	.	PUNCT
dti-2520	313	1	2016;22(6):458	2016;22(6):458	NUM
dti-2520	313	2	-	-	PUNCT
dti-2520	313	3	478	478	NUM
dti-2520	313	4	.	.	PUNCT
dti-2520	314	1	crossref	crossref	PROPN
dti-2520	314	2	pubmed	pubmed	PROPN
dti-2520	314	3	37	37	NUM
dti-2520	314	4	.	.	PUNCT
dti-2520	315	1	shimizu	shimizu	PROPN
dti-2520	315	2	k	k	PROPN
dti-2520	315	3	,	,	PUNCT
dti-2520	315	4	yamada	yamada	PROPN
dti-2520	315	5	t	t	PROPN
dti-2520	315	6	,	,	PUNCT
dti-2520	315	7	ogura	ogura	PROPN
dti-2520	315	8	h	h	PROPN
dti-2520	315	9	,	,	PUNCT
dti-2520	315	10	et	et	PROPN
dti-2520	315	11	al	al	PROPN
dti-2520	315	12	.	.	PUNCT
dti-2520	315	13	synbiotics	synbiotic	NOUN
dti-2520	315	14	modulate	modulate	VERB
dti-2520	315	15	gut	gut	NOUN
dti-2520	315	16	microbiota	microbiota	NOUN
dti-2520	315	17	and	and	CCONJ
dti-2520	315	18	reduce	reduce	VERB
dti-2520	315	19	enteritis	enteritis	NOUN
dti-2520	315	20	and	and	CCONJ
dti-2520	315	21	ventilator	ventilator	NOUN
dti-2520	315	22	-	-	PUNCT
dti-2520	315	23	associated	associate	VERB
dti-2520	315	24	pneumonia	pneumonia	NOUN
dti-2520	315	25	in	in	ADP
dti-2520	315	26	patients	patient	NOUN
dti-2520	315	27	with	with	ADP
dti-2520	315	28	sepsis	sepsis	NOUN
dti-2520	315	29	:	:	PUNCT
dti-2520	315	30	a	a	DET
dti-2520	315	31	randomized	randomized	ADJ
dti-2520	315	32	controlled	control	VERB
dti-2520	315	33	trial	trial	NOUN
dti-2520	315	34	.	.	PUNCT
dti-2520	316	1	crit	crit	PROPN
dti-2520	316	2	care	care	NOUN
dti-2520	316	3	.	.	PUNCT
dti-2520	317	1	2018;22(1):239	2018;22(1):239	NUM
dti-2520	317	2	.	.	PUNCT
dti-2520	318	1	crossref	crossref	PROPN
dti-2520	318	2	pubmed	pubmed	PROPN
dti-2520	318	3	38	38	NUM
dti-2520	318	4	.	.	PUNCT
dti-2520	319	1	lange	lange	PROPN
dti-2520	319	2	k	k	NOUN
dti-2520	319	3	,	,	PUNCT
dti-2520	319	4	buerger	buerger	NOUN
dti-2520	319	5	m	m	PROPN
dti-2520	319	6	,	,	PUNCT
dti-2520	319	7	stallmach	stallmach	VERB
dti-2520	319	8	a	a	NOUN
dti-2520	319	9	,	,	PUNCT
dti-2520	319	10	bruns	brun	NOUN
dti-2520	319	11	t.	t.	NOUN
dti-2520	319	12	effects	effect	NOUN
dti-2520	319	13	of	of	ADP
dti-2520	319	14	antibiotics	antibiotic	NOUN
dti-2520	319	15	on	on	ADP
dti-2520	319	16	gut	gut	NOUN
dti-2520	319	17	microbiota	microbiota	NOUN
dti-2520	319	18	.	.	PUNCT
dti-2520	320	1	dig	dig	VERB
dti-2520	320	2	dis	dis	PROPN
dti-2520	320	3	.	.	PUNCT
dti-2520	321	1	2016;34(3):260	2016;34(3):260	NUM
dti-2520	321	2	-	-	PUNCT
dti-2520	321	3	268	268	NUM
dti-2520	321	4	.	.	PUNCT
dti-2520	322	1	crossref	crossref	PROPN
dti-2520	322	2	pubmed	pubmed	PROPN
dti-2520	322	3	39	39	NUM
dti-2520	322	4	.	.	PUNCT
dti-2520	323	1	shin	shin	PROPN
dti-2520	323	2	nr	nr	PROPN
dti-2520	323	3	,	,	PUNCT
dti-2520	323	4	whon	whon	PROPN
dti-2520	323	5	tw	tw	PROPN
dti-2520	323	6	,	,	PUNCT
dti-2520	324	1	bae	bae	PROPN
dti-2520	324	2	jw	jw	PROPN
dti-2520	324	3	.	.	PROPN
dti-2520	324	4	proteobacteria	proteobacteria	PROPN
dti-2520	324	5	:	:	PUNCT
dti-2520	324	6	microbial	microbial	ADJ
dti-2520	324	7	signature	signature	NOUN
dti-2520	324	8	of	of	ADP
dti-2520	324	9	dysbiosis	dysbiosis	NOUN
dti-2520	324	10	in	in	ADP
dti-2520	324	11	gut	gut	NOUN
dti-2520	324	12	microbiota	microbiota	NOUN
dti-2520	324	13	.	.	PUNCT
dti-2520	325	1	trends	trend	NOUN
dti-2520	325	2	biotechnol	biotechnol	VERB
dti-2520	325	3	.	.	PUNCT
dti-2520	326	1	2015;33(9):496	2015;33(9):496	NOUN
dti-2520	326	2	-	-	SYM
dti-2520	326	3	503	503	NUM
dti-2520	326	4	.	.	PUNCT
dti-2520	327	1	crossref	crossref	PROPN
dti-2520	327	2	pubmed	pubmed	PROPN
dti-2520	327	3	40	40	NUM
dti-2520	327	4	.	.	PUNCT
dti-2520	328	1	graspeuntner	graspeuntner	PROPN
dti-2520	328	2	s	s	PROPN
dti-2520	328	3	,	,	PUNCT
dti-2520	328	4	waschina	waschina	PROPN
dti-2520	328	5	s	s	PROPN
dti-2520	328	6	,	,	PUNCT
dti-2520	328	7	künzel	künzel	PROPN
dti-2520	328	8	s	s	PROPN
dti-2520	328	9	,	,	PUNCT
dti-2520	328	10	et	et	PROPN
dti-2520	328	11	al	al	AUX
dti-2520	328	12	.	.	PUNCT
dti-2520	328	13	gut	gut	VERB
dti-2520	328	14	dysbiosis	dysbiosis	NOUN
dti-2520	328	15	with	with	ADP
dti-2520	328	16	bacilli	bacilli	NOUN
dti-2520	328	17	dominance	dominance	NOUN
dti-2520	328	18	and	and	CCONJ
dti-2520	328	19	accumulation	accumulation	NOUN
dti-2520	328	20	of	of	ADP
dti-2520	328	21	fermentation	fermentation	NOUN
dti-2520	328	22	products	product	NOUN
dti-2520	328	23	precedes	precede	VERB
dti-2520	328	24	late	late	ADJ
dti-2520	328	25	-	-	PUNCT
dti-2520	328	26	onset	onset	NOUN
dti-2520	328	27	sepsis	sepsis	NOUN
dti-2520	328	28	in	in	ADP
dti-2520	328	29	preterm	preterm	ADJ
dti-2520	328	30	infants	infant	NOUN
dti-2520	328	31	.	.	PUNCT
dti-2520	329	1	clin	clin	PROPN
dti-2520	329	2	infect	infect	PROPN
dti-2520	329	3	dis	dis	PROPN
dti-2520	329	4	.	.	PUNCT
dti-2520	330	1	2019;69(2):268	2019;69(2):268	PROPN
dti-2520	330	2	-	-	PUNCT
dti-2520	330	3	277	277	NUM
dti-2520	330	4	.	.	PUNCT
dti-2520	331	1	crossref	crossref	PROPN
dti-2520	331	2	pubmed	pubmed	PROPN
dti-2520	331	3	41	41	NUM
dti-2520	331	4	.	.	PUNCT
dti-2520	332	1	hoytema	hoytema	PROPN
dti-2520	332	2	van	van	PROPN
dti-2520	332	3	konijnenburg	konijnenburg	PROPN
dti-2520	332	4	dp	dp	PROPN
dti-2520	332	5	,	,	PUNCT
dti-2520	332	6	reis	reis	NOUN
dti-2520	332	7	bs	bs	NOUN
dti-2520	332	8	,	,	PUNCT
dti-2520	332	9	pedicord	pedicord	PROPN
dti-2520	332	10	va	va	PROPN
dti-2520	332	11	,	,	PUNCT
dti-2520	332	12	farache	farache	PROPN
dti-2520	332	13	j	j	PROPN
dti-2520	332	14	,	,	PUNCT
dti-2520	332	15	victora	victora	PROPN
dti-2520	332	16	gd	gd	PROPN
dti-2520	332	17	,	,	PUNCT
dti-2520	332	18	mucida	mucida	PROPN
dti-2520	332	19	d.	d.	PROPN
dti-2520	332	20	intestinal	intestinal	ADJ
dti-2520	332	21	epithelial	epithelial	ADJ
dti-2520	332	22	and	and	CCONJ
dti-2520	332	23	intraepithelial	intraepithelial	ADJ
dti-2520	332	24	t	t	PROPN
dti-2520	332	25	cell	cell	NOUN
dti-2520	332	26	crosstalk	crosstalk	NOUN
dti-2520	332	27	mediates	mediate	VERB
dti-2520	332	28	a	a	DET
dti-2520	332	29	dynamic	dynamic	ADJ
dti-2520	332	30	response	response	NOUN
dti-2520	332	31	to	to	ADP
dti-2520	332	32	infection	infection	NOUN
dti-2520	332	33	.	.	PUNCT
dti-2520	333	1	cell	cell	NOUN
dti-2520	333	2	.	.	PUNCT
dti-2520	334	1	2017;171(4):783	2017;171(4):783	NUM
dti-2520	334	2	-	-	SYM
dti-2520	334	3	794.e13	794.e13	PROPN
dti-2520	334	4	.	.	PUNCT
dti-2520	335	1	crossref	crossref	PROPN
dti-2520	335	2	pubmed	pubmed	PROPN
dti-2520	335	3	42	42	NUM
dti-2520	335	4	.	.	PUNCT
dti-2520	336	1	saez	saez	PROPN
dti-2520	336	2	a	a	PROPN
dti-2520	336	3	,	,	PUNCT
dti-2520	336	4	gomez	gomez	PROPN
dti-2520	336	5	-	-	PUNCT
dti-2520	336	6	bris	bris	PROPN
dti-2520	336	7	r	r	NOUN
dti-2520	336	8	,	,	PUNCT
dti-2520	336	9	herrero	herrero	PROPN
dti-2520	336	10	-	-	PUNCT
dti-2520	336	11	fernandez	fernandez	PROPN
dti-2520	336	12	b	b	PROPN
dti-2520	336	13	,	,	PUNCT
dti-2520	336	14	mingorance	mingorance	NOUN
dti-2520	336	15	c	c	NOUN
dti-2520	336	16	,	,	PUNCT
dti-2520	336	17	rius	rius	NOUN
dti-2520	336	18	c	c	NOUN
dti-2520	336	19	,	,	PUNCT
dti-2520	336	20	gonzalez	gonzalez	PROPN
dti-2520	336	21	-	-	PUNCT
dti-2520	336	22	granado	granado	PROPN
dti-2520	336	23	jm	jm	PROPN
dti-2520	336	24	.	.	PROPN
dti-2520	336	25	innate	innate	ADJ
dti-2520	336	26	lymphoid	lymphoid	ADJ
dti-2520	336	27	cells	cell	NOUN
dti-2520	336	28	in	in	ADP
dti-2520	336	29	intestinal	intestinal	ADJ
dti-2520	336	30	homeostasis	homeostasis	NOUN
dti-2520	336	31	and	and	CCONJ
dti-2520	336	32	inflammatory	inflammatory	ADJ
dti-2520	336	33	bowel	bowel	NOUN
dti-2520	336	34	disease	disease	NOUN
dti-2520	336	35	.	.	PUNCT
dti-2520	337	1	int	int	PROPN
dti-2520	337	2	j	j	PROPN
dti-2520	337	3	mol	mol	ADP
dti-2520	337	4	sci	sci	PROPN
dti-2520	337	5	.	.	PUNCT
dti-2520	338	1	2021;22(14):7618	2021;22(14):7618	X
dti-2520	338	2	.	.	PUNCT
dti-2520	339	1	crossref	crossref	PROPN
dti-2520	339	2	pubmed	pubmed	PROPN
dti-2520	339	3	43	43	NUM
dti-2520	339	4	.	.	PUNCT
dti-2520	340	1	li	li	PROPN
dti-2520	340	2	y	y	PROPN
dti-2520	340	3	,	,	PUNCT
dti-2520	340	4	jin	jin	PROPN
dti-2520	340	5	l	l	PROPN
dti-2520	340	6	,	,	PUNCT
dti-2520	340	7	chen	chen	PROPN
dti-2520	340	8	t.	t.	PROPN
dti-2520	340	9	the	the	DET
dti-2520	340	10	effects	effect	NOUN
dti-2520	340	11	of	of	ADP
dti-2520	340	12	secretory	secretory	NOUN
dti-2520	340	13	iga	iga	PROPN
dti-2520	340	14	in	in	ADP
dti-2520	340	15	the	the	DET
dti-2520	340	16	mucosal	mucosal	ADJ
dti-2520	340	17	immune	immune	ADJ
dti-2520	340	18	system	system	NOUN
dti-2520	340	19	.	.	PUNCT
dti-2520	340	20	biomed	biome	VERB
dti-2520	340	21	res	re	NOUN
dti-2520	340	22	int	int	NOUN
dti-2520	340	23	.	.	PUNCT
dti-2520	341	1	2020;2020:2032057	2020;2020:2032057	NUM
dti-2520	341	2	.	.	PUNCT
dti-2520	342	1	crossref	crossref	PROPN
dti-2520	342	2	pubmed	pubmed	PROPN
dti-2520	342	3	44	44	NUM
dti-2520	342	4	.	.	PUNCT
dti-2520	343	1	agus	agus	PROPN
dti-2520	343	2	a	a	PROPN
dti-2520	343	3	,	,	PUNCT
dti-2520	343	4	planchais	planchais	PROPN
dti-2520	343	5	j	j	PROPN
dti-2520	343	6	,	,	PUNCT
dti-2520	343	7	sokol	sokol	PROPN
dti-2520	343	8	h.	h.	PROPN
dti-2520	343	9	gut	gut	PROPN
dti-2520	343	10	microbiota	microbiota	NOUN
dti-2520	343	11	regulation	regulation	NOUN
dti-2520	343	12	of	of	ADP
dti-2520	343	13	tryptophan	tryptophan	NOUN
dti-2520	343	14	metabolism	metabolism	NOUN
dti-2520	343	15	in	in	ADP
dti-2520	343	16	health	health	NOUN
dti-2520	343	17	and	and	CCONJ
dti-2520	343	18	disease	disease	NOUN
dti-2520	343	19	.	.	PUNCT
dti-2520	344	1	cell	cell	NOUN
dti-2520	344	2	host	host	NOUN
dti-2520	344	3	microbe	microbe	NOUN
dti-2520	344	4	.	.	PUNCT
dti-2520	345	1	2018;23(6):716	2018;23(6):716	NOUN
dti-2520	345	2	-	-	SYM
dti-2520	345	3	724	724	NUM
dti-2520	345	4	.	.	PUNCT
dti-2520	346	1	crossref	crossref	PROPN
dti-2520	346	2	pubmed	pubmed	PROPN
dti-2520	346	3	45	45	NUM
dti-2520	346	4	.	.	PUNCT
dti-2520	347	1	ma	ma	PROPN
dti-2520	347	2	h	h	PROPN
dti-2520	347	3	,	,	PUNCT
dti-2520	347	4	qiu	qiu	PROPN
dti-2520	347	5	y	y	PROPN
dti-2520	347	6	,	,	PUNCT
dti-2520	347	7	yang	yang	PROPN
dti-2520	347	8	h.	h.	PROPN
dti-2520	347	9	intestinal	intestinal	ADJ
dti-2520	347	10	intraepithelial	intraepithelial	ADJ
dti-2520	347	11	lymphocytes	lymphocyte	NOUN
dti-2520	347	12	:	:	PUNCT
dti-2520	347	13	maintainers	maintainer	NOUN
dti-2520	347	14	of	of	ADP
dti-2520	347	15	intestinal	intestinal	ADJ
dti-2520	347	16	immune	immune	ADJ
dti-2520	347	17	tolerance	tolerance	NOUN
dti-2520	347	18	and	and	CCONJ
dti-2520	347	19	regulators	regulator	NOUN
dti-2520	347	20	of	of	ADP
dti-2520	347	21	intestinal	intestinal	ADJ
dti-2520	347	22	immunity	immunity	NOUN
dti-2520	347	23	.	.	PUNCT
dti-2520	348	1	j	j	PROPN
dti-2520	348	2	leukoc	leukoc	VERB
dti-2520	348	3	biol	biol	PROPN
dti-2520	348	4	.	.	PUNCT
dti-2520	349	1	2021;109(2):339	2021;109(2):339	NUM
dti-2520	349	2	-	-	SYM
dti-2520	349	3	347	347	NUM
dti-2520	349	4	.	.	PUNCT
dti-2520	350	1	crossref	crossref	PROPN
dti-2520	350	2	pubmed	pubmed	PROPN
dti-2520	350	3	46	46	NUM
dti-2520	350	4	.	.	PUNCT
dti-2520	351	1	panda	panda	NOUN
dti-2520	351	2	sk	sk	NOUN
dti-2520	351	3	,	,	PUNCT
dti-2520	351	4	colonna	colonna	NOUN
dti-2520	351	5	m.	m.	NOUN
dti-2520	351	6	innate	innate	ADJ
dti-2520	351	7	lymphoid	lymphoid	NOUN
dti-2520	351	8	cells	cell	NOUN
dti-2520	351	9	in	in	ADP
dti-2520	351	10	mucosal	mucosal	NOUN
dti-2520	351	11	immunity	immunity	NOUN
dti-2520	351	12	.	.	PUNCT
dti-2520	352	1	front	front	ADJ
dti-2520	352	2	immunol	immunol	NOUN
dti-2520	352	3	.	.	PUNCT
dti-2520	353	1	2019;10:861	2019;10:861	NOUN
dti-2520	353	2	.	.	PUNCT
dti-2520	354	1	crossref	crossref	PROPN
dti-2520	354	2	pubmed	pubmed	PROPN
dti-2520	354	3	https://doi.org/10.4103/ijmr.ijmr_1517_16	https://doi.org/10.4103/ijmr.ijmr_1517_16	PROPN
dti-2520	354	4	https://www.ncbi.nlm.nih.gov/pubmed/29749365	https://www.ncbi.nlm.nih.gov/pubmed/29749365	PROPN
dti-2520	354	5	https://doi.org/10.4103/ijmr.ijmr_214_18	https://doi.org/10.4103/ijmr.ijmr_214_18	PROPN
dti-2520	354	6	https://www.ncbi.nlm.nih.gov/pubmed/31219073	https://www.ncbi.nlm.nih.gov/pubmed/31219073	X
dti-2520	354	7	https://doi.org/10.1177/1049732320919088	https://doi.org/10.1177/1049732320919088	X
dti-2520	354	8	https://www.ncbi.nlm.nih.gov/pubmed/32458726	https://www.ncbi.nlm.nih.gov/pubmed/32458726	NUM
dti-2520	354	9	https://doi.org/10.1080/14787210.2018.1438262	https://doi.org/10.1080/14787210.2018.1438262	PROPN
dti-2520	354	10	https://www.ncbi.nlm.nih.gov/pubmed/29406800	https://www.ncbi.nlm.nih.gov/pubmed/29406800	NUM
dti-2520	354	11	https://doi.org/10.1001/jamapediatrics.2020.0593	https://doi.org/10.1001/jamapediatrics.2020.0593	PROPN
dti-2520	355	1	https://www.ncbi.nlm.nih.gov/pubmed/32364598	https://www.ncbi.nlm.nih.gov/pubmed/32364598	PRON
dti-2520	355	2	https://doi.org/10.1186/s13756-020-00760-3	https://doi.org/10.1186/s13756-020-00760-3	NOUN
dti-2520	355	3	https://www.ncbi.nlm.nih.gov/pubmed/32641109	https://www.ncbi.nlm.nih.gov/pubmed/32641109	NUM
dti-2520	355	4	https://doi.org/10.1371/journal.pone.0224490	https://doi.org/10.1371/journal.pone.0224490	PROPN
dti-2520	355	5	https://www.ncbi.nlm.nih.gov/pubmed/31661535	https://www.ncbi.nlm.nih.gov/pubmed/31661535	PROPN
dti-2520	355	6	https://doi.org/10.1186/s13054-020-02989-1	https://doi.org/10.1186/s13054-020-02989-1	NUM
dti-2520	355	7	https://www.ncbi.nlm.nih.gov/pubmed/32487252	https://www.ncbi.nlm.nih.gov/pubmed/32487252	NUM
dti-2520	356	1	https://doi.org/10.3389/fimmu.2020.571731	https://doi.org/10.3389/fimmu.2020.571731	PROPN
dti-2520	356	2	https://www.ncbi.nlm.nih.gov/pubmed/33178196	https://www.ncbi.nlm.nih.gov/pubmed/33178196	X
dti-2520	356	3	https://doi.org/10.3389/fcimb.2021.625913	https://doi.org/10.3389/fcimb.2021.625913	PROPN
dti-2520	356	4	https://www.ncbi.nlm.nih.gov/pubmed/33816335	https://www.ncbi.nlm.nih.gov/pubmed/33816335	NUM
dti-2520	356	5	https://doi.org/10.1016/s2468-1253(16)30119-4	https://doi.org/10.1016/s2468-1253(16)30119-4	NOUN
dti-2520	356	6	https://www.ncbi.nlm.nih.gov/pubmed/28403983	https://www.ncbi.nlm.nih.gov/pubmed/28403983	NUM
dti-2520	356	7	https://doi.org/10.1007/s00018-018-2943-4	https://doi.org/10.1007/s00018-018-2943-4	NUM
dti-2520	356	8	https://www.ncbi.nlm.nih.gov/pubmed/30317530	https://www.ncbi.nlm.nih.gov/pubmed/30317530	NUM
dti-2520	356	9	https://doi.org/10.3390/nu11071613	https://doi.org/10.3390/nu11071613	PROPN
dti-2520	356	10	https://www.ncbi.nlm.nih.gov/pubmed/31315227	https://www.ncbi.nlm.nih.gov/pubmed/31315227	NUM
dti-2520	356	11	https://doi.org/10.3390/medicina56020088	https://doi.org/10.3390/medicina56020088	NOUN
dti-2520	356	12	https://www.ncbi.nlm.nih.gov/pubmed/32098430	https://www.ncbi.nlm.nih.gov/pubmed/32098430	NUM
dti-2520	356	13	https://doi.org/10.3390/cells9051234	https://doi.org/10.3390/cells9051234	NOUN
dti-2520	356	14	https://www.ncbi.nlm.nih.gov/pubmed/32429359	https://www.ncbi.nlm.nih.gov/pubmed/32429359	PROPN
dti-2520	356	15	https://doi.org/10.1007/s10482-020-01474-7	https://doi.org/10.1007/s10482-020-01474-7	NUM
dti-2520	356	16	https://www.ncbi.nlm.nih.gov/pubmed/33136284	https://www.ncbi.nlm.nih.gov/pubmed/33136284	NUM
dti-2520	356	17	https://doi.org/10.1073/pnas.1415174111	https://doi.org/10.1073/pnas.1415174111	PROPN
dti-2520	356	18	https://www.ncbi.nlm.nih.gov/pubmed/25288760	https://www.ncbi.nlm.nih.gov/pubmed/25288760	NUM
dti-2520	356	19	https://doi.org/10.3233/jad-200306	https://doi.org/10.3233/jad-200306	NOUN
dti-2520	356	20	https://www.ncbi.nlm.nih.gov/pubmed/33074224	https://www.ncbi.nlm.nih.gov/pubmed/33074224	NUM
dti-2520	356	21	https://doi.org/10.1016/j.gtc.2016.09.007	https://doi.org/10.1016/j.gtc.2016.09.007	VERB
dti-2520	356	22	https://www.ncbi.nlm.nih.gov/pubmed/28164854	https://www.ncbi.nlm.nih.gov/pubmed/28164854	X
dti-2520	356	23	https://doi.org/10.1164/rccm.201504-0781oc	https://doi.org/10.1164/rccm.201504-0781oc	NOUN
dti-2520	356	24	https://www.ncbi.nlm.nih.gov/pubmed/26414292	https://www.ncbi.nlm.nih.gov/pubmed/26414292	NUM
dti-2520	356	25	https://doi.org/10.1001/jamanetworkopen.2018.7571	https://doi.org/10.1001/jamanetworkopen.2018.7571	PROPN
dti-2520	356	26	https://www.ncbi.nlm.nih.gov/pubmed/30768188	https://www.ncbi.nlm.nih.gov/pubmed/30768188	ADP
dti-2520	356	27	https://doi.org/10.1615/critrevimmunol.2015015461	https://doi.org/10.1615/critrevimmunol.2015015461	ADJ
dti-2520	356	28	https://www.ncbi.nlm.nih.gov/pubmed/26757392	https://www.ncbi.nlm.nih.gov/pubmed/26757392	NUM
dti-2520	356	29	https://doi.org/10.1016/j.cyto.2016.09.010	https://doi.org/10.1016/j.cyto.2016.09.010	X
dti-2520	356	30	https://www.ncbi.nlm.nih.gov/pubmed/27676155	https://www.ncbi.nlm.nih.gov/pubmed/27676155	NUM
dti-2520	356	31	https://doi.org/10.1016/j.molimm.2021.04.005	https://doi.org/10.1016/j.molimm.2021.04.005	PROPN
dti-2520	356	32	https://www.ncbi.nlm.nih.gov/pubmed/34087625	https://www.ncbi.nlm.nih.gov/pubmed/34087625	NUM
dti-2520	357	1	https://doi.org/10.1016/j.jep.2019.112139	https://doi.org/10.1016/j.jep.2019.112139	PROPN
dti-2520	358	1	https://www.ncbi.nlm.nih.gov/pubmed/31401318	https://www.ncbi.nlm.nih.gov/pubmed/31401318	VERB
dti-2520	358	2	https://doi.org/10.1186/s40168-018-0441-4	https://doi.org/10.1186/s40168-018-0441-4	NUM
dti-2520	358	3	https://www.ncbi.nlm.nih.gov/pubmed/29615110	https://www.ncbi.nlm.nih.gov/pubmed/29615110	PROPN
dti-2520	358	4	https://doi.org/10.1016/j.molmed.2016.04.003	https://doi.org/10.1016/j.molmed.2016.04.003	PROPN
dti-2520	358	5	https://www.ncbi.nlm.nih.gov/pubmed/27178527	https://www.ncbi.nlm.nih.gov/pubmed/27178527	PROPN
dti-2520	358	6	https://doi.org/10.1186/s13054-018-2167-x	https://doi.org/10.1186/s13054-018-2167-x	NOUN
dti-2520	358	7	https://www.ncbi.nlm.nih.gov/pubmed/30261905	https://www.ncbi.nlm.nih.gov/pubmed/30261905	NUM
dti-2520	358	8	https://doi.org/10.1159/000443360	https://doi.org/10.1159/000443360	NOUN
dti-2520	358	9	https://www.ncbi.nlm.nih.gov/pubmed/27028893	https://www.ncbi.nlm.nih.gov/pubmed/27028893	NUM
dti-2520	358	10	https://doi.org/10.1016/j.tibtech.2015.06.011	https://doi.org/10.1016/j.tibtech.2015.06.011	PROPN
dti-2520	358	11	https://www.ncbi.nlm.nih.gov/pubmed/26210164	https://www.ncbi.nlm.nih.gov/pubmed/26210164	X
dti-2520	358	12	https://doi.org/10.1093/cid/ciy882	https://doi.org/10.1093/cid/ciy882	PROPN
dti-2520	358	13	https://www.ncbi.nlm.nih.gov/pubmed/30329017	https://www.ncbi.nlm.nih.gov/pubmed/30329017	CCONJ
dti-2520	358	14	https://doi.org/10.1016/j.cell.2017.08.046	https://doi.org/10.1016/j.cell.2017.08.046	NOUN
dti-2520	358	15	https://www.ncbi.nlm.nih.gov/pubmed/28942917	https://www.ncbi.nlm.nih.gov/pubmed/28942917	X
dti-2520	358	16	https://doi.org/10.3390/ijms22147618	https://doi.org/10.3390/ijms22147618	NOUN
dti-2520	358	17	https://www.ncbi.nlm.nih.gov/pubmed/34299236	https://www.ncbi.nlm.nih.gov/pubmed/34299236	X
dti-2520	358	18	https://doi.org/10.1155/2020/2032057	https://doi.org/10.1155/2020/2032057	PROPN
dti-2520	358	19	https://www.ncbi.nlm.nih.gov/pubmed/31998782	https://www.ncbi.nlm.nih.gov/pubmed/31998782	X
dti-2520	358	20	https://doi.org/10.1016/j.chom.2018.05.003	https://doi.org/10.1016/j.chom.2018.05.003	PROPN
dti-2520	358	21	https://www.ncbi.nlm.nih.gov/pubmed/29902437	https://www.ncbi.nlm.nih.gov/pubmed/29902437	NUM
dti-2520	358	22	https://doi.org/10.1002/jlb.3ru0220-111	https://doi.org/10.1002/jlb.3ru0220-111	NOUN
dti-2520	358	23	https://www.ncbi.nlm.nih.gov/pubmed/32678936	https://www.ncbi.nlm.nih.gov/pubmed/32678936	NUM
dti-2520	359	1	https://doi.org/10.3389/fimmu.2019.00861	https://doi.org/10.3389/fimmu.2019.00861	PROPN
dti-2520	359	2	https://www.ncbi.nlm.nih.gov/pubmed/31134050	https://www.ncbi.nlm.nih.gov/pubmed/31134050	NUM
dti-2520	359	3	kalra	kalra	PROPN
dti-2520	359	4	et	et	PROPN
dti-2520	359	5	al	al	PROPN
dti-2520	359	6	drug	drug	PROPN
dti-2520	359	7	target	target	NOUN
dti-2520	359	8	insights	insight	NOUN
dti-2520	359	9	2022	2022	NUM
dti-2520	359	10	;	;	PUNCT
dti-2520	359	11	16	16	NUM
dti-2520	359	12	:	:	SYM
dti-2520	359	13	87	87	NUM
dti-2520	359	14	©	©	PROPN
dti-2520	359	15	2022	2022	NUM
dti-2520	359	16	the	the	DET
dti-2520	359	17	authors	author	NOUN
dti-2520	359	18	.	.	PUNCT
dti-2520	360	1	published	publish	VERB
dti-2520	360	2	by	by	ADP
dti-2520	360	3	aboutscience	aboutscience	NOUN
dti-2520	360	4	www.aboutscience.eu	www.aboutscience.eu	NOUN
dti-2520	360	5	47	47	NUM
dti-2520	360	6	.	.	PUNCT
dti-2520	361	1	gensollen	gensollen	PROPN
dti-2520	361	2	t	t	PROPN
dti-2520	361	3	,	,	PUNCT
dti-2520	361	4	iyer	iyer	PROPN
dti-2520	361	5	ss	ss	PROPN
dti-2520	361	6	,	,	PUNCT
dti-2520	361	7	kasper	kasper	PROPN
dti-2520	361	8	dl	dl	PROPN
dti-2520	361	9	,	,	PUNCT
dti-2520	361	10	blumberg	blumberg	PROPN
dti-2520	361	11	rs	rs	PROPN
dti-2520	361	12	.	.	PUNCT
dti-2520	362	1	how	how	SCONJ
dti-2520	362	2	colonization	colonization	NOUN
dti-2520	362	3	by	by	ADP
dti-2520	362	4	microbiota	microbiota	NOUN
dti-2520	362	5	in	in	ADP
dti-2520	362	6	early	early	ADJ
dti-2520	362	7	life	life	NOUN
dti-2520	362	8	shapes	shape	VERB
dti-2520	362	9	the	the	DET
dti-2520	362	10	immune	immune	ADJ
dti-2520	362	11	system	system	NOUN
dti-2520	362	12	.	.	PUNCT
dti-2520	363	1	science	science	NOUN
dti-2520	363	2	.	.	PUNCT
dti-2520	364	1	2016;352(6285):539	2016;352(6285):539	NUM
dti-2520	364	2	-	-	SYM
dti-2520	364	3	544	544	NUM
dti-2520	364	4	.	.	PUNCT
dti-2520	365	1	crossref	crossref	PROPN
dti-2520	365	2	pubmed	pubmed	PROPN
dti-2520	365	3	48	48	NUM
dti-2520	365	4	.	.	PUNCT
dti-2520	366	1	hapfelmeier	hapfelmeier	PROPN
dti-2520	366	2	s	s	PROPN
dti-2520	366	3	,	,	PUNCT
dti-2520	366	4	lawson	lawson	PROPN
dti-2520	366	5	mae	mae	PROPN
dti-2520	366	6	,	,	PUNCT
dti-2520	366	7	slack	slack	VERB
dti-2520	366	8	e	e	NOUN
dti-2520	366	9	,	,	PUNCT
dti-2520	366	10	et	et	PROPN
dti-2520	366	11	al	al	PROPN
dti-2520	366	12	.	.	PUNCT
dti-2520	367	1	reversible	reversible	ADJ
dti-2520	367	2	microbial	microbial	ADJ
dti-2520	367	3	colonization	colonization	NOUN
dti-2520	367	4	of	of	ADP
dti-2520	367	5	germ	germ	NOUN
dti-2520	367	6	-	-	PUNCT
dti-2520	367	7	free	free	ADJ
dti-2520	367	8	mice	mouse	NOUN
dti-2520	367	9	reveals	reveal	VERB
dti-2520	367	10	the	the	DET
dti-2520	367	11	dynamics	dynamic	NOUN
dti-2520	367	12	of	of	ADP
dti-2520	367	13	iga	iga	PROPN
dti-2520	367	14	immune	immune	ADJ
dti-2520	367	15	responses	response	NOUN
dti-2520	367	16	.	.	PUNCT
dti-2520	368	1	science	science	NOUN
dti-2520	368	2	.	.	PUNCT
dti-2520	369	1	2010;328(5986):1705	2010;328(5986):1705	NUM
dti-2520	369	2	-	-	SYM
dti-2520	369	3	1709	1709	NUM
dti-2520	369	4	.	.	PUNCT
dti-2520	370	1	crossref	crossref	PROPN
dti-2520	370	2	pubmed	pubmed	PROPN
dti-2520	370	3	49	49	NUM
dti-2520	370	4	.	.	PUNCT
dti-2520	371	1	hernández	hernández	PROPN
dti-2520	371	2	-	-	PUNCT
dti-2520	371	3	chirlaque	chirlaque	NOUN
dti-2520	371	4	c	c	NOUN
dti-2520	371	5	,	,	PUNCT
dti-2520	371	6	aranda	aranda	PROPN
dti-2520	371	7	cj	cj	PROPN
dti-2520	371	8	,	,	PUNCT
dti-2520	371	9	ocón	ocón	PROPN
dti-2520	371	10	b	b	AUX
dti-2520	371	11	,	,	PUNCT
dti-2520	371	12	et	et	PROPN
dti-2520	371	13	al	al	PROPN
dti-2520	371	14	.	.	PROPN
dti-2520	371	15	germ	germ	NOUN
dti-2520	371	16	-	-	PUNCT
dti-2520	371	17	free	free	ADJ
dti-2520	371	18	and	and	CCONJ
dti-2520	371	19	antibiotic	antibiotic	ADJ
dti-2520	371	20	-	-	PUNCT
dti-2520	371	21	treated	treat	VERB
dti-2520	371	22	mice	mouse	NOUN
dti-2520	371	23	are	be	AUX
dti-2520	371	24	highly	highly	ADV
dti-2520	371	25	susceptible	susceptible	ADJ
dti-2520	371	26	to	to	ADP
dti-2520	371	27	epithelial	epithelial	ADJ
dti-2520	371	28	injury	injury	NOUN
dti-2520	371	29	in	in	ADP
dti-2520	371	30	dss	dss	NOUN
dti-2520	371	31	colitis	colitis	NOUN
dti-2520	371	32	.	.	PUNCT
dti-2520	372	1	j	j	PROPN
dti-2520	372	2	crohn	crohn	PROPN
dti-2520	372	3	’s	’s	PART
dti-2520	372	4	colitis	colitis	NOUN
dti-2520	372	5	.	.	PUNCT
dti-2520	373	1	2016;10(11):1324	2016;10(11):1324	NUM
dti-2520	373	2	-	-	SYM
dti-2520	373	3	1335	1335	NUM
dti-2520	373	4	.	.	PUNCT
dti-2520	374	1	crossref	crossref	PROPN
dti-2520	374	2	pubmed	pubmed	PROPN
dti-2520	374	3	50	50	NUM
dti-2520	374	4	.	.	PUNCT
dti-2520	375	1	rooks	rooks	PROPN
dti-2520	375	2	mg	mg	PROPN
dti-2520	375	3	,	,	PUNCT
dti-2520	375	4	garrett	garrett	PROPN
dti-2520	375	5	ws	ws	PROPN
dti-2520	375	6	.	.	PUNCT
dti-2520	376	1	gut	gut	NOUN
dti-2520	376	2	microbiota	microbiota	NOUN
dti-2520	376	3	,	,	PUNCT
dti-2520	376	4	metabolites	metabolite	NOUN
dti-2520	376	5	and	and	CCONJ
dti-2520	376	6	host	host	NOUN
dti-2520	376	7	immunity	immunity	NOUN
dti-2520	376	8	.	.	PUNCT
dti-2520	377	1	nat	nat	PROPN
dti-2520	377	2	rev	rev	PROPN
dti-2520	377	3	immunol	immunol	NOUN
dti-2520	377	4	.	.	PUNCT
dti-2520	378	1	2016;16(6):341	2016;16(6):341	NUM
dti-2520	378	2	-	-	PUNCT
dti-2520	378	3	352	352	NUM
dti-2520	378	4	.	.	PUNCT
dti-2520	378	5	crossref	crossref	PROPN
dti-2520	378	6	pubmed	pubmed	PROPN
dti-2520	378	7	https://doi.org/10.1126/science.aad9378	https://doi.org/10.1126/science.aad9378	PROPN
dti-2520	378	8	https://www.ncbi.nlm.nih.gov/pubmed/27126036	https://www.ncbi.nlm.nih.gov/pubmed/27126036	NUM
dti-2520	378	9	https://doi.org/10.1126/science.1188454	https://doi.org/10.1126/science.1188454	NOUN
dti-2520	378	10	https://www.ncbi.nlm.nih.gov/pubmed/20576892	https://www.ncbi.nlm.nih.gov/pubmed/20576892	NUM
dti-2520	378	11	https://doi.org/10.1093/ecco-jcc/jjw096	https://doi.org/10.1093/ecco-jcc/jjw096	ADP
dti-2520	378	12	https://www.ncbi.nlm.nih.gov/pubmed/27117829	https://www.ncbi.nlm.nih.gov/pubmed/27117829	X
dti-2520	378	13	https://doi.org/10.1038/nri.2016.42	https://doi.org/10.1038/nri.2016.42	NOUN
dti-2520	378	14	https://www.ncbi.nlm.nih.gov/pubmed/27231050	https://www.ncbi.nlm.nih.gov/pubmed/27231050	X