id	sid	tid	token	lemma	pos
dti-2574	1	1	dti	dti	PROPN
dti-2574	1	2	drug	drug	PROPN
dti-2574	1	3	target	target	NOUN
dti-2574	1	4	insights	insight	NOUN
dti-2574	1	5	2023	2023	NUM
dti-2574	1	6	;	;	PUNCT
dti-2574	1	7	17	17	NUM
dti-2574	1	8	:	:	SYM
dti-2574	1	9	39	39	NUM
dti-2574	1	10	-	-	SYM
dti-2574	1	11	44	44	NUM
dti-2574	1	12	issn	issn	PROPN
dti-2574	1	13	1177	1177	NUM
dti-2574	1	14	-	-	SYM
dti-2574	1	15	3928	3928	NUM
dti-2574	1	16	|	|	ADV
dti-2574	1	17	doi	doi	NOUN
dti-2574	1	18	:	:	PUNCT
dti-2574	1	19	10.33393	10.33393	NUM
dti-2574	1	20	/	/	SYM
dti-2574	1	21	dti.2023.2574	dti.2023.2574	ADJ
dti-2574	1	22	original	original	ADJ
dti-2574	1	23	research	research	NOUN
dti-2574	1	24	article	article	NOUN
dti-2574	1	25	drug	drug	NOUN
dti-2574	1	26	target	target	NOUN
dti-2574	1	27	insights	insight	NOUN
dti-2574	1	28	issn	issn	VERB
dti-2574	1	29	1177	1177	NUM
dti-2574	1	30	-	-	SYM
dti-2574	1	31	3928	3928	NUM
dti-2574	1	32	www.aboutscience.eu/dti	www.aboutscience.eu/dti	NOUN
dti-2574	1	33	©	©	PROPN
dti-2574	1	34	2023	2023	NUM
dti-2574	1	35	the	the	DET
dti-2574	1	36	authors	author	NOUN
dti-2574	1	37	.	.	PUNCT
dti-2574	2	1	this	this	DET
dti-2574	2	2	article	article	NOUN
dti-2574	2	3	is	be	AUX
dti-2574	2	4	published	publish	VERB
dti-2574	2	5	by	by	ADP
dti-2574	2	6	aboutscience	aboutscience	NOUN
dti-2574	2	7	and	and	CCONJ
dti-2574	2	8	licensed	license	VERB
dti-2574	2	9	under	under	ADP
dti-2574	2	10	creative	creative	ADJ
dti-2574	2	11	commons	common	NOUN
dti-2574	2	12	attribution	attribution	NOUN
dti-2574	2	13	-	-	PUNCT
dti-2574	2	14	noncommercial	noncommercial	ADJ
dti-2574	2	15	4.0	4.0	NUM
dti-2574	2	16	international	international	NOUN
dti-2574	2	17	(	(	PUNCT
dti-2574	2	18	cc	cc	NOUN
dti-2574	2	19	by	by	ADP
dti-2574	2	20	-	-	PUNCT
dti-2574	2	21	nc	nc	PROPN
dti-2574	2	22	4.0	4.0	NUM
dti-2574	2	23	)	)	PUNCT
dti-2574	2	24	.	.	PUNCT
dti-2574	3	1	commercial	commercial	ADJ
dti-2574	3	2	use	use	NOUN
dti-2574	3	3	is	be	AUX
dti-2574	3	4	not	not	PART
dti-2574	3	5	permitted	permit	VERB
dti-2574	3	6	and	and	CCONJ
dti-2574	3	7	is	be	AUX
dti-2574	3	8	subject	subject	ADJ
dti-2574	3	9	to	to	ADP
dti-2574	3	10	publisher	publisher	NOUN
dti-2574	3	11	’s	’s	PART
dti-2574	3	12	permissions	permission	NOUN
dti-2574	3	13	.	.	PUNCT
dti-2574	4	1	full	full	ADJ
dti-2574	4	2	information	information	NOUN
dti-2574	4	3	is	be	AUX
dti-2574	4	4	available	available	ADJ
dti-2574	4	5	at	at	ADP
dti-2574	4	6	www.aboutscience.eu	www.aboutscience.eu	NOUN
dti-2574	4	7	treatment	treatment	NOUN
dti-2574	4	8	with	with	ADP
dti-2574	4	9	levosimendan	levosimendan	PROPN
dti-2574	4	10	in	in	ADP
dti-2574	4	11	an	an	DET
dti-2574	4	12	experimental	experimental	ADJ
dti-2574	4	13	model	model	NOUN
dti-2574	4	14	of	of	ADP
dti-2574	4	15	early	early	ADJ
dti-2574	4	16	ventilator	ventilator	NOUN
dti-2574	4	17	-	-	PUNCT
dti-2574	4	18	induced	induce	VERB
dti-2574	4	19	diaphragmatic	diaphragmatic	ADJ
dti-2574	4	20	dysfunction	dysfunction	NOUN
dti-2574	4	21	vanessa	vanessa	PROPN
dti-2574	4	22	zambelli1	zambelli1	PROPN
dti-2574	4	23	,	,	PUNCT
dti-2574	4	24	emma	emma	PROPN
dti-2574	4	25	j.	j.	PROPN
dti-2574	4	26	murphy2	murphy2	PROPN
dti-2574	4	27	,	,	PUNCT
dti-2574	4	28	paolo	paolo	PROPN
dti-2574	4	29	delvecchio1	delvecchio1	PROPN
dti-2574	4	30	,	,	PUNCT
dti-2574	4	31	laura	laura	PROPN
dti-2574	4	32	rizzi1	rizzi1	PROPN
dti-2574	4	33	,	,	PUNCT
dti-2574	4	34	roberto	roberto	PROPN
dti-2574	4	35	fumagalli1,3	fumagalli1,3	PROPN
dti-2574	4	36	,	,	PUNCT
dti-2574	4	37	emanuele	emanuele	PROPN
dti-2574	4	38	rezoagli1,4	rezoagli1,4	PROPN
dti-2574	4	39	,	,	PUNCT
dti-2574	4	40	giacomo	giacomo	NOUN
dti-2574	4	41	bellani1,4	bellani1,4	PROPN
dti-2574	5	1	1school	1school	NUM
dti-2574	5	2	of	of	ADP
dti-2574	5	3	medicine	medicine	NOUN
dti-2574	5	4	and	and	CCONJ
dti-2574	5	5	surgery	surgery	NOUN
dti-2574	5	6	,	,	PUNCT
dti-2574	5	7	university	university	NOUN
dti-2574	5	8	of	of	ADP
dti-2574	5	9	milano	milano	PROPN
dti-2574	5	10	-	-	PUNCT
dti-2574	5	11	bicocca	bicocca	PROPN
dti-2574	5	12	,	,	PUNCT
dti-2574	5	13	monza	monza	PROPN
dti-2574	5	14	italy	italy	PROPN
dti-2574	5	15	2life	2life	PROPN
dti-2574	5	16	–	–	PUNCT
dti-2574	5	17	health	health	NOUN
dti-2574	5	18	and	and	CCONJ
dti-2574	5	19	bioscience	bioscience	PROPN
dti-2574	5	20	research	research	PROPN
dti-2574	5	21	institute	institute	PROPN
dti-2574	5	22	,	,	PUNCT
dti-2574	5	23	midwest	midwest	PROPN
dti-2574	5	24	campus	campus	PROPN
dti-2574	5	25	,	,	PUNCT
dti-2574	5	26	technological	technological	ADJ
dti-2574	5	27	university	university	NOUN
dti-2574	5	28	of	of	ADP
dti-2574	5	29	the	the	DET
dti-2574	5	30	shannon	shannon	PROPN
dti-2574	5	31	,	,	PUNCT
dti-2574	5	32	limerick	limerick	PROPN
dti-2574	5	33	ireland	ireland	PROPN
dti-2574	5	34	3department	3department	NUM
dti-2574	5	35	of	of	ADP
dti-2574	5	36	emergency	emergency	NOUN
dti-2574	5	37	medicine	medicine	NOUN
dti-2574	5	38	,	,	PUNCT
dti-2574	5	39	asst	asst	NOUN
dti-2574	5	40	grande	grande	PROPN
dti-2574	5	41	ospedale	ospedale	PROPN
dti-2574	5	42	metropolitano	metropolitano	PROPN
dti-2574	5	43	niguarda	niguarda	PROPN
dti-2574	5	44	,	,	PUNCT
dti-2574	5	45	milan	milan	PROPN
dti-2574	5	46	italy	italy	PROPN
dti-2574	5	47	4	4	NUM
dti-2574	5	48	department	department	NOUN
dti-2574	5	49	of	of	ADP
dti-2574	5	50	emergency	emergency	NOUN
dti-2574	5	51	and	and	CCONJ
dti-2574	5	52	intensive	intensive	ADJ
dti-2574	5	53	care	care	NOUN
dti-2574	5	54	,	,	PUNCT
dti-2574	5	55	fondazione	fondazione	PROPN
dti-2574	5	56	irccs	ircc	VERB
dti-2574	5	57	san	san	PROPN
dti-2574	5	58	gerardo	gerardo	PROPN
dti-2574	5	59	dei	dei	PROPN
dti-2574	5	60	tintori	tintori	PROPN
dti-2574	5	61	,	,	PUNCT
dti-2574	5	62	monza	monza	PROPN
dti-2574	5	63	italy	italy	PROPN
dti-2574	5	64	abstract	abstract	ADJ
dti-2574	5	65	introduction	introduction	NOUN
dti-2574	5	66	:	:	PUNCT
dti-2574	5	67	mechanical	mechanical	ADJ
dti-2574	5	68	ventilation	ventilation	NOUN
dti-2574	5	69	(	(	PUNCT
dti-2574	5	70	mv	mv	NOUN
dti-2574	5	71	)	)	PUNCT
dti-2574	5	72	is	be	AUX
dti-2574	5	73	a	a	DET
dti-2574	5	74	life	life	NOUN
dti-2574	5	75	-	-	PUNCT
dti-2574	5	76	saving	save	VERB
dti-2574	5	77	approach	approach	NOUN
dti-2574	5	78	in	in	ADP
dti-2574	5	79	critically	critically	ADV
dti-2574	5	80	ill	ill	ADJ
dti-2574	5	81	patients	patient	NOUN
dti-2574	5	82	.	.	PUNCT
dti-2574	6	1	however	however	ADV
dti-2574	6	2	,	,	PUNCT
dti-2574	6	3	it	it	PRON
dti-2574	6	4	may	may	AUX
dti-2574	6	5	affect	affect	VERB
dti-2574	6	6	the	the	DET
dti-2574	6	7	diaphragmatic	diaphragmatic	ADJ
dti-2574	6	8	structure	structure	NOUN
dti-2574	6	9	and	and	CCONJ
dti-2574	6	10	function	function	NOUN
dti-2574	6	11	,	,	PUNCT
dti-2574	6	12	beyond	beyond	ADP
dti-2574	6	13	the	the	DET
dti-2574	6	14	lungs	lung	NOUN
dti-2574	6	15	.	.	PUNCT
dti-2574	7	1	levosimendan	levosimendan	PROPN
dti-2574	7	2	is	be	AUX
dti-2574	7	3	a	a	DET
dti-2574	7	4	calcium	calcium	NOUN
dti-2574	7	5	sensitizer	sensitizer	NOUN
dti-2574	7	6	widely	widely	ADV
dti-2574	7	7	used	use	VERB
dti-2574	7	8	in	in	ADP
dti-2574	7	9	clinics	clinic	NOUN
dti-2574	7	10	to	to	PART
dti-2574	7	11	improve	improve	VERB
dti-2574	7	12	cardiac	cardiac	ADJ
dti-2574	7	13	contractility	contractility	NOUN
dti-2574	7	14	in	in	ADP
dti-2574	7	15	acute	acute	ADJ
dti-2574	7	16	heart	heart	NOUN
dti-2574	7	17	failure	failure	NOUN
dti-2574	7	18	patients	patient	NOUN
dti-2574	7	19	.	.	PUNCT
dti-2574	8	1	in	in	ADP
dti-2574	8	2	vitro	vitro	X
dti-2574	8	3	studies	study	NOUN
dti-2574	8	4	have	have	AUX
dti-2574	8	5	demonstrated	demonstrate	VERB
dti-2574	8	6	that	that	SCONJ
dti-2574	8	7	levosimendan	levosimendan	PROPN
dti-2574	8	8	increased	increase	VERB
dti-2574	8	9	force	force	NOUN
dti-2574	8	10	-	-	PUNCT
dti-2574	8	11	generating	generate	VERB
dti-2574	8	12	capacity	capacity	NOUN
dti-2574	8	13	of	of	ADP
dti-2574	8	14	the	the	DET
dti-2574	8	15	diaphragm	diaphragm	NOUN
dti-2574	8	16	in	in	ADP
dti-2574	8	17	chronic	chronic	ADJ
dti-2574	8	18	obstructive	obstructive	ADJ
dti-2574	8	19	pulmonary	pulmonary	ADJ
dti-2574	8	20	disease	disease	NOUN
dti-2574	8	21	patients	patient	NOUN
dti-2574	8	22	.	.	PUNCT
dti-2574	9	1	thus	thus	ADV
dti-2574	9	2	the	the	DET
dti-2574	9	3	aim	aim	NOUN
dti-2574	9	4	of	of	ADP
dti-2574	9	5	this	this	DET
dti-2574	9	6	study	study	NOUN
dti-2574	9	7	was	be	AUX
dti-2574	9	8	to	to	PART
dti-2574	9	9	evaluate	evaluate	VERB
dti-2574	9	10	the	the	DET
dti-2574	9	11	effects	effect	NOUN
dti-2574	9	12	of	of	ADP
dti-2574	9	13	levosimendan	levosimendan	PROPN
dti-2574	9	14	administration	administration	PROPN
dti-2574	9	15	in	in	ADP
dti-2574	9	16	an	an	DET
dti-2574	9	17	animal	animal	NOUN
dti-2574	9	18	model	model	NOUN
dti-2574	9	19	of	of	ADP
dti-2574	9	20	ventilator	ventilator	NOUN
dti-2574	9	21	-	-	PUNCT
dti-2574	9	22	induced	induce	VERB
dti-2574	9	23	diaphragmatic	diaphragmatic	ADJ
dti-2574	9	24	dysfunction	dysfunction	NOUN
dti-2574	9	25	(	(	PUNCT
dti-2574	9	26	vidd	vidd	NOUN
dti-2574	9	27	)	)	PUNCT
dti-2574	9	28	on	on	ADP
dti-2574	9	29	muscle	muscle	NOUN
dti-2574	9	30	contraction	contraction	NOUN
dti-2574	9	31	and	and	CCONJ
dti-2574	9	32	diaphragm	diaphragm	NOUN
dti-2574	9	33	muscle	muscle	NOUN
dti-2574	9	34	cell	cell	NOUN
dti-2574	9	35	viability	viability	NOUN
dti-2574	9	36	.	.	PUNCT
dti-2574	10	1	methods	method	NOUN
dti-2574	10	2	:	:	PUNCT
dti-2574	10	3	sprague	sprague	NOUN
dti-2574	10	4	-	-	PUNCT
dti-2574	10	5	dawley	dawley	NOUN
dti-2574	10	6	rats	rat	NOUN
dti-2574	10	7	underwent	undergo	VERB
dti-2574	10	8	prolonged	prolonged	ADJ
dti-2574	10	9	mv	mv	PROPN
dti-2574	10	10	(	(	PUNCT
dti-2574	10	11	5	5	NUM
dti-2574	10	12	hours	hour	NOUN
dti-2574	10	13	)	)	PUNCT
dti-2574	10	14	.	.	PUNCT
dti-2574	11	1	vidd+levo	vidd+levo	PROPN
dti-2574	11	2	group	group	NOUN
dti-2574	11	3	received	receive	VERB
dti-2574	11	4	a	a	DET
dti-2574	11	5	starting	starting	NOUN
dti-2574	11	6	bolus	bolus	NOUN
dti-2574	11	7	of	of	ADP
dti-2574	11	8	levosimendan	levosimendan	PROPN
dti-2574	11	9	immediately	immediately	ADV
dti-2574	11	10	after	after	ADP
dti-2574	11	11	intratracheal	intratracheal	NOUN
dti-2574	11	12	intubation	intubation	NOUN
dti-2574	11	13	and	and	CCONJ
dti-2574	11	14	then	then	ADV
dti-2574	11	15	an	an	DET
dti-2574	11	16	intravenous	intravenous	ADJ
dti-2574	11	17	infusion	infusion	NOUN
dti-2574	11	18	of	of	ADP
dti-2574	11	19	levosimendan	levosimendan	PROPN
dti-2574	11	20	throughout	throughout	ADP
dti-2574	11	21	the	the	DET
dti-2574	11	22	study	study	NOUN
dti-2574	11	23	.	.	PUNCT
dti-2574	12	1	diaphragms	diaphragm	NOUN
dti-2574	12	2	were	be	AUX
dti-2574	12	3	collected	collect	VERB
dti-2574	12	4	for	for	ADP
dti-2574	12	5	ex	ex	PRON
dti-2574	12	6	vivo	vivo	NOUN
dti-2574	12	7	contractility	contractility	NOUN
dti-2574	12	8	measurement	measurement	NOUN
dti-2574	12	9	(	(	PUNCT
dti-2574	12	10	with	with	ADP
dti-2574	12	11	electric	electric	ADJ
dti-2574	12	12	stimulation	stimulation	NOUN
dti-2574	12	13	)	)	PUNCT
dti-2574	12	14	,	,	PUNCT
dti-2574	12	15	histological	histological	ADJ
dti-2574	12	16	analysis	analysis	NOUN
dti-2574	12	17	and	and	CCONJ
dti-2574	12	18	western	western	ADJ
dti-2574	12	19	blot	blot	NOUN
dti-2574	12	20	analysis	analysis	NOUN
dti-2574	12	21	.	.	PUNCT
dti-2574	13	1	healthy	healthy	ADJ
dti-2574	13	2	rats	rat	NOUN
dti-2574	13	3	were	be	AUX
dti-2574	13	4	used	use	VERB
dti-2574	13	5	as	as	ADP
dti-2574	13	6	the	the	DET
dti-2574	13	7	control	control	NOUN
dti-2574	13	8	.	.	PUNCT
dti-2574	14	1	results	result	NOUN
dti-2574	14	2	:	:	PUNCT
dti-2574	14	3	levosimendan	levosimendan	ADJ
dti-2574	14	4	treatment	treatment	NOUN
dti-2574	14	5	maintained	maintain	VERB
dti-2574	14	6	an	an	DET
dti-2574	14	7	adequate	adequate	ADJ
dti-2574	14	8	mean	mean	NOUN
dti-2574	14	9	arterial	arterial	ADJ
dti-2574	14	10	pressure	pressure	NOUN
dti-2574	14	11	during	during	ADP
dti-2574	14	12	the	the	DET
dti-2574	14	13	entire	entire	ADJ
dti-2574	14	14	experimental	experimental	ADJ
dti-2574	14	15	protocol	protocol	NOUN
dti-2574	14	16	,	,	PUNCT
dti-2574	14	17	preserved	preserve	VERB
dti-2574	14	18	levels	level	NOUN
dti-2574	14	19	of	of	ADP
dti-2574	14	20	autophagy	autophagy	ADV
dti-2574	14	21	-	-	PUNCT
dti-2574	14	22	related	relate	VERB
dti-2574	14	23	proteins	protein	NOUN
dti-2574	14	24	(	(	PUNCT
dti-2574	14	25	lc3bi	lc3bi	NOUN
dti-2574	14	26	and	and	CCONJ
dti-2574	14	27	lc3bii	lc3bii	NOUN
dti-2574	14	28	)	)	PUNCT
dti-2574	14	29	and	and	CCONJ
dti-2574	14	30	the	the	DET
dti-2574	14	31	muscular	muscular	ADJ
dti-2574	14	32	cell	cell	NOUN
dti-2574	14	33	diameter	diameter	NOUN
dti-2574	14	34	demonstrated	demonstrate	VERB
dti-2574	14	35	by	by	ADP
dti-2574	14	36	histological	histological	ADJ
dti-2574	14	37	analysis	analysis	NOUN
dti-2574	14	38	.	.	PUNCT
dti-2574	15	1	levosimendan	levosimendan	PROPN
dti-2574	15	2	did	do	AUX
dti-2574	15	3	not	not	PART
dti-2574	15	4	affect	affect	VERB
dti-2574	15	5	the	the	DET
dti-2574	15	6	diaphragmatic	diaphragmatic	ADJ
dti-2574	15	7	contraction	contraction	NOUN
dti-2574	15	8	or	or	CCONJ
dti-2574	15	9	the	the	DET
dti-2574	15	10	levels	level	NOUN
dti-2574	15	11	of	of	ADP
dti-2574	15	12	proteins	protein	NOUN
dti-2574	15	13	involved	involve	VERB
dti-2574	15	14	in	in	ADP
dti-2574	15	15	the	the	DET
dti-2574	15	16	protein	protein	NOUN
dti-2574	15	17	degradation	degradation	NOUN
dti-2574	15	18	(	(	PUNCT
dti-2574	15	19	atrogin	atrogin	NOUN
dti-2574	15	20	)	)	PUNCT
dti-2574	15	21	.	.	PUNCT
dti-2574	16	1	conclusions	conclusion	NOUN
dti-2574	16	2	:	:	PUNCT
dti-2574	16	3	our	our	PRON
dti-2574	16	4	data	datum	NOUN
dti-2574	16	5	suggest	suggest	VERB
dti-2574	16	6	that	that	SCONJ
dti-2574	16	7	levosimendan	levosimendan	PROPN
dti-2574	16	8	preserves	preserve	VERB
dti-2574	16	9	muscular	muscular	ADJ
dti-2574	16	10	cell	cell	NOUN
dti-2574	16	11	structure	structure	NOUN
dti-2574	16	12	(	(	PUNCT
dti-2574	16	13	cross	cross	ADJ
dti-2574	16	14	-	-	ADJ
dti-2574	16	15	sectional	sectional	ADJ
dti-2574	16	16	area	area	NOUN
dti-2574	16	17	)	)	PUNCT
dti-2574	16	18	and	and	CCONJ
dti-2574	16	19	muscle	muscle	NOUN
dti-2574	16	20	autophagy	autophagy	ADV
dti-2574	16	21	after	after	ADP
dti-2574	16	22	5	5	NUM
dti-2574	16	23	hours	hour	NOUN
dti-2574	16	24	of	of	ADP
dti-2574	16	25	mv	mv	PROPN
dti-2574	16	26	in	in	ADP
dti-2574	16	27	a	a	DET
dti-2574	16	28	rat	rat	NOUN
dti-2574	16	29	model	model	NOUN
dti-2574	16	30	of	of	ADP
dti-2574	16	31	vidd	vidd	NOUN
dti-2574	16	32	.	.	PUNCT
dti-2574	17	1	however	however	ADV
dti-2574	17	2	,	,	PUNCT
dti-2574	17	3	levosimendan	levosimendan	PROPN
dti-2574	17	4	did	do	AUX
dti-2574	17	5	not	not	PART
dti-2574	17	6	improve	improve	VERB
dti-2574	17	7	diaphragm	diaphragm	NOUN
dti-2574	17	8	contractile	contractile	NOUN
dti-2574	17	9	efficiency	efficiency	NOUN
dti-2574	17	10	.	.	PUNCT
dti-2574	18	1	keywords	keyword	NOUN
dti-2574	18	2	:	:	PUNCT
dti-2574	18	3	diaphragm	diaphragm	PROPN
dti-2574	18	4	contractility	contractility	NOUN
dti-2574	18	5	,	,	PUNCT
dti-2574	18	6	levosimendan	levosimendan	PROPN
dti-2574	18	7	,	,	PUNCT
dti-2574	18	8	mechanical	mechanical	ADJ
dti-2574	18	9	ventilation	ventilation	NOUN
dti-2574	18	10	,	,	PUNCT
dti-2574	18	11	muscle	muscle	NOUN
dti-2574	18	12	fiber	fiber	NOUN
dti-2574	18	13	size	size	NOUN
dti-2574	18	14	,	,	PUNCT
dti-2574	18	15	ventilator	ventilator	NOUN
dti-2574	18	16	-	-	PUNCT
dti-2574	18	17	induced	induce	VERB
dti-2574	18	18	diaphragmatic	diaphragmatic	ADJ
dti-2574	18	19	dysfunction	dysfunction	NOUN
dti-2574	18	20	received	receive	VERB
dti-2574	18	21	:	:	PUNCT
dti-2574	18	22	february	february	PROPN
dti-2574	18	23	11	11	NUM
dti-2574	18	24	,	,	PUNCT
dti-2574	18	25	2023	2023	NUM
dti-2574	18	26	accepted	accept	VERB
dti-2574	18	27	:	:	PUNCT
dti-2574	18	28	march	march	PROPN
dti-2574	18	29	29	29	NUM
dti-2574	18	30	,	,	PUNCT
dti-2574	18	31	2023	2023	NUM
dti-2574	18	32	published	publish	VERB
dti-2574	18	33	online	online	ADV
dti-2574	18	34	:	:	PUNCT
dti-2574	18	35	april	april	PROPN
dti-2574	18	36	13	13	NUM
dti-2574	18	37	,	,	PUNCT
dti-2574	18	38	2023	2023	NUM
dti-2574	18	39	corresponding	correspond	VERB
dti-2574	18	40	author	author	NOUN
dti-2574	18	41	:	:	PUNCT
dti-2574	18	42	giacomo	giacomo	PROPN
dti-2574	18	43	bellani	bellani	PROPN
dti-2574	18	44	&	&	CCONJ
dti-2574	18	45	emanuele	emanuele	PROPN
dti-2574	18	46	rezoagli	rezoagli	PROPN
dti-2574	18	47	school	school	NOUN
dti-2574	18	48	of	of	ADP
dti-2574	18	49	medicine	medicine	NOUN
dti-2574	18	50	and	and	CCONJ
dti-2574	18	51	surgery	surgery	NOUN
dti-2574	18	52	university	university	PROPN
dti-2574	18	53	of	of	ADP
dti-2574	18	54	milano	milano	PROPN
dti-2574	18	55	-	-	PUNCT
dti-2574	18	56	bicocca	bicocca	PROPN
dti-2574	18	57	via	via	ADP
dti-2574	18	58	cadore	cadore	ADJ
dti-2574	18	59	48	48	NUM
dti-2574	18	60	,	,	PUNCT
dti-2574	18	61	20900	20900	NUM
dti-2574	18	62	monza	monza	NOUN
dti-2574	18	63	(	(	PUNCT
dti-2574	18	64	mb	mb	NOUN
dti-2574	18	65	)	)	PUNCT
dti-2574	18	66	italy	italy	PROPN
dti-2574	18	67	giacomo.bellani1@unimib.it	giacomo.bellani1@unimib.it	PROPN
dti-2574	18	68	;	;	PUNCT
dti-2574	18	69	emanuele.rezoagli@unimib.it	emanuele.rezoagli@unimib.it	VERB
dti-2574	18	70	a	a	DET
dti-2574	18	71	rapid	rapid	ADJ
dti-2574	18	72	impairment	impairment	NOUN
dti-2574	18	73	of	of	ADP
dti-2574	18	74	both	both	DET
dti-2574	18	75	lungs	lung	NOUN
dti-2574	18	76	(	(	PUNCT
dti-2574	18	77	i.e.	i.e.	X
dti-2574	18	78	,	,	PUNCT
dti-2574	18	79	ventilator	ventilator	NOUN
dti-2574	18	80	-	-	PUNCT
dti-2574	18	81	induced	induce	VERB
dti-2574	18	82	lung	lung	NOUN
dti-2574	18	83	injury	injury	NOUN
dti-2574	18	84	–	–	PUNCT
dti-2574	18	85	vili	vili	NOUN
dti-2574	18	86	)	)	PUNCT
dti-2574	18	87	and	and	CCONJ
dti-2574	18	88	diaphragm	diaphragm	NOUN
dti-2574	18	89	(	(	PUNCT
dti-2574	18	90	i.e.	i.e.	X
dti-2574	18	91	,	,	PUNCT
dti-2574	18	92	ventilator	ventilator	NOUN
dti-2574	18	93	-	-	PUNCT
dti-2574	18	94	induced	induce	VERB
dti-2574	18	95	diaphragmatic	diaphragmatic	ADJ
dti-2574	18	96	dysfunction	dysfunction	NOUN
dti-2574	18	97	–	–	PUNCT
dti-2574	18	98	vidd	vidd	NOUN
dti-2574	18	99	)	)	PUNCT
dti-2574	18	100	.	.	PUNCT
dti-2574	19	1	mv	mv	PROPN
dti-2574	19	2	can	can	AUX
dti-2574	19	3	also	also	ADV
dti-2574	19	4	exacerbate	exacerbate	VERB
dti-2574	19	5	a	a	DET
dti-2574	19	6	preexisting	preexist	VERB
dti-2574	19	7	vili	vili	NOUN
dti-2574	19	8	(	(	PUNCT
dti-2574	19	9	1	1	NUM
dti-2574	19	10	-	-	SYM
dti-2574	19	11	3	3	NUM
dti-2574	19	12	)	)	PUNCT
dti-2574	19	13	.	.	PUNCT
dti-2574	20	1	it	it	PRON
dti-2574	20	2	is	be	AUX
dti-2574	20	3	also	also	ADV
dti-2574	20	4	associated	associate	VERB
dti-2574	20	5	with	with	ADP
dti-2574	20	6	adverse	adverse	ADJ
dti-2574	20	7	effects	effect	NOUN
dti-2574	20	8	on	on	ADP
dti-2574	20	9	multiple	multiple	ADJ
dti-2574	20	10	aspects	aspect	NOUN
dti-2574	20	11	of	of	ADP
dti-2574	20	12	diaphragmatic	diaphragmatic	ADJ
dti-2574	20	13	structure	structure	NOUN
dti-2574	20	14	and	and	CCONJ
dti-2574	20	15	function	function	NOUN
dti-2574	20	16	(	(	PUNCT
dti-2574	20	17	vidd	vidd	NOUN
dti-2574	20	18	)	)	PUNCT
dti-2574	20	19	(	(	PUNCT
dti-2574	20	20	4	4	NUM
dti-2574	20	21	)	)	PUNCT
dti-2574	20	22	.	.	PUNCT
dti-2574	21	1	the	the	DET
dti-2574	21	2	detrimental	detrimental	ADJ
dti-2574	21	3	impact	impact	NOUN
dti-2574	21	4	of	of	ADP
dti-2574	21	5	prolonged	prolonged	ADJ
dti-2574	21	6	mv	mv	PROPN
dti-2574	21	7	on	on	ADP
dti-2574	21	8	the	the	DET
dti-2574	21	9	diaphragm	diaphragm	NOUN
dti-2574	21	10	is	be	AUX
dti-2574	21	11	strictly	strictly	ADV
dti-2574	21	12	correlated	correlate	VERB
dti-2574	21	13	to	to	ADP
dti-2574	21	14	problems	problem	NOUN
dti-2574	21	15	in	in	ADP
dti-2574	21	16	weaning	weaning	NOUN
dti-2574	21	17	patients	patient	NOUN
dti-2574	21	18	from	from	ADP
dti-2574	21	19	the	the	DET
dti-2574	21	20	ventilator	ventilator	NOUN
dti-2574	21	21	(	(	PUNCT
dti-2574	21	22	5	5	NUM
dti-2574	21	23	)	)	PUNCT
dti-2574	21	24	.	.	PUNCT
dti-2574	22	1	the	the	DET
dti-2574	22	2	incidence	incidence	NOUN
dti-2574	22	3	level	level	NOUN
dti-2574	22	4	can	can	AUX
dti-2574	22	5	reach	reach	VERB
dti-2574	22	6	35	35	NUM
dti-2574	22	7	%	%	NOUN
dti-2574	22	8	of	of	ADP
dti-2574	22	9	patients	patient	NOUN
dti-2574	22	10	exposed	expose	VERB
dti-2574	22	11	to	to	ADP
dti-2574	22	12	prolonged	prolonged	ADJ
dti-2574	22	13	mv	mv	PROPN
dti-2574	22	14	,	,	PUNCT
dti-2574	22	15	with	with	ADP
dti-2574	22	16	subsequent	subsequent	ADJ
dti-2574	22	17	increase	increase	NOUN
dti-2574	22	18	in	in	ADP
dti-2574	22	19	morbidity	morbidity	NOUN
dti-2574	22	20	and	and	CCONJ
dti-2574	22	21	mortality	mortality	NOUN
dti-2574	22	22	(	(	PUNCT
dti-2574	22	23	4,6,7	4,6,7	NOUN
dti-2574	22	24	)	)	PUNCT
dti-2574	22	25	.	.	PUNCT
dti-2574	23	1	furthermore	furthermore	ADV
dti-2574	23	2	,	,	PUNCT
dti-2574	23	3	body	body	NOUN
dti-2574	23	4	composition	composition	NOUN
dti-2574	23	5	indexes	index	NOUN
dti-2574	23	6	are	be	AUX
dti-2574	23	7	known	know	VERB
dti-2574	23	8	to	to	PART
dti-2574	23	9	predict	predict	VERB
dti-2574	23	10	outcome	outcome	NOUN
dti-2574	23	11	–	–	PUNCT
dti-2574	23	12	such	such	ADJ
dti-2574	23	13	as	as	ADP
dti-2574	23	14	mortality	mortality	NOUN
dti-2574	23	15	and	and	CCONJ
dti-2574	23	16	mv	mv	PROPN
dti-2574	23	17	duration	duration	NOUN
dti-2574	23	18	itself	itself	PRON
dti-2574	23	19	–	–	PUNCT
dti-2574	23	20	in	in	ADP
dti-2574	23	21	critically	critically	ADV
dti-2574	23	22	ill	ill	ADJ
dti-2574	23	23	patients	patient	NOUN
dti-2574	23	24	(	(	PUNCT
dti-2574	23	25	8)	8)	NUM
dti-2574	23	26	.	.	PUNCT
dti-2574	24	1	the	the	DET
dti-2574	24	2	first	first	ADJ
dti-2574	24	3	evidence	evidence	NOUN
dti-2574	24	4	on	on	ADP
dti-2574	24	5	the	the	DET
dti-2574	24	6	correlation	correlation	NOUN
dti-2574	24	7	between	between	ADP
dti-2574	24	8	mv	mv	PROPN
dti-2574	24	9	and	and	CCONJ
dti-2574	24	10	vidd	vidd	NOUN
dti-2574	24	11	was	be	AUX
dti-2574	24	12	published	publish	VERB
dti-2574	24	13	almost	almost	ADV
dti-2574	24	14	35	35	NUM
dti-2574	24	15	years	year	NOUN
dti-2574	24	16	ago	ago	ADV
dti-2574	24	17	,	,	PUNCT
dti-2574	24	18	in	in	ADP
dti-2574	24	19	which	which	PRON
dti-2574	24	20	a	a	DET
dti-2574	24	21	study	study	NOUN
dti-2574	24	22	of	of	ADP
dti-2574	24	23	infant	infant	NOUN
dti-2574	24	24	and	and	CCONJ
dti-2574	24	25	neonates	neonate	NOUN
dti-2574	24	26	suggested	suggest	VERB
dti-2574	24	27	that	that	SCONJ
dti-2574	24	28	mv	mv	PROPN
dti-2574	24	29	predisposes	predispose	VERB
dti-2574	24	30	diaphragm	diaphragm	ADJ
dti-2574	24	31	fibers	fiber	NOUN
dti-2574	24	32	to	to	ADP
dti-2574	24	33	atrophy	atrophy	NOUN
dti-2574	24	34	(	(	PUNCT
dti-2574	24	35	9	9	NUM
dti-2574	24	36	)	)	PUNCT
dti-2574	24	37	.	.	PUNCT
dti-2574	25	1	thenceforth	thenceforth	VERB
dti-2574	25	2	introduction	introduction	NOUN
dti-2574	25	3	mechanical	mechanical	ADJ
dti-2574	25	4	ventilation	ventilation	NOUN
dti-2574	25	5	(	(	PUNCT
dti-2574	25	6	mv	mv	NOUN
dti-2574	25	7	)	)	PUNCT
dti-2574	25	8	is	be	AUX
dti-2574	25	9	a	a	DET
dti-2574	25	10	life	life	NOUN
dti-2574	25	11	support	support	NOUN
dti-2574	25	12	technique	technique	NOUN
dti-2574	25	13	used	use	VERB
dti-2574	25	14	in	in	ADP
dti-2574	25	15	critically	critically	ADV
dti-2574	25	16	ill	ill	ADJ
dti-2574	25	17	patients	patient	NOUN
dti-2574	25	18	.	.	PUNCT
dti-2574	26	1	however	however	ADV
dti-2574	26	2	,	,	PUNCT
dti-2574	26	3	prolonged	prolonged	ADJ
dti-2574	26	4	mv	mv	PROPN
dti-2574	26	5	is	be	AUX
dti-2574	26	6	also	also	ADV
dti-2574	26	7	associated	associate	VERB
dti-2574	26	8	with	with	ADP
dti-2574	26	9	numerous	numerous	ADJ
dti-2574	26	10	potential	potential	ADJ
dti-2574	26	11	complications	complication	NOUN
dti-2574	26	12	including	include	VERB
dti-2574	26	13	https://doi.org/10.33393/dti.2023.2574	https://doi.org/10.33393/dti.2023.2574	NOUN
dti-2574	26	14	https://creativecommons.org/licenses/by-nc/4.0/legalcode	https://creativecommons.org/licenses/by-nc/4.0/legalcode	NOUN
dti-2574	26	15	mailto:vanessa.zambelli@unimib.it	mailto:vanessa.zambelli@unimib.it	PROPN
dti-2574	26	16	effects	effect	NOUN
dti-2574	26	17	of	of	ADP
dti-2574	26	18	levosimendan	levosimendan	ADJ
dti-2574	26	19	treatment	treatment	NOUN
dti-2574	26	20	on	on	ADP
dti-2574	26	21	diaphragmatic	diaphragmatic	ADJ
dti-2574	26	22	injury40	injury40	NOUN
dti-2574	26	23	©	©	ADP
dti-2574	26	24	2023	2023	NUM
dti-2574	26	25	the	the	DET
dti-2574	26	26	authors	author	NOUN
dti-2574	26	27	.	.	PUNCT
dti-2574	27	1	drug	drug	NOUN
dti-2574	27	2	target	target	NOUN
dti-2574	27	3	insights	insight	NOUN
dti-2574	27	4	issn	issn	VERB
dti-2574	27	5	1177	1177	NUM
dti-2574	27	6	-	-	SYM
dti-2574	27	7	3928	3928	NUM
dti-2574	27	8	www.aboutscience.eu/dti	www.aboutscience.eu/dti	VERB
dti-2574	27	9	numerous	numerous	ADJ
dti-2574	27	10	experimental	experimental	ADJ
dti-2574	27	11	and	and	CCONJ
dti-2574	27	12	clinical	clinical	ADJ
dti-2574	27	13	studies	study	NOUN
dti-2574	27	14	documented	document	VERB
dti-2574	27	15	that	that	SCONJ
dti-2574	27	16	prolonged	prolong	VERB
dti-2574	27	17	mv	mv	PROPN
dti-2574	27	18	induces	induce	VERB
dti-2574	27	19	a	a	DET
dti-2574	27	20	rapid	rapid	ADJ
dti-2574	27	21	muscular	muscular	ADJ
dti-2574	27	22	atrophy	atrophy	NOUN
dti-2574	27	23	and	and	CCONJ
dti-2574	27	24	contractile	contractile	ADJ
dti-2574	27	25	dysfunction	dysfunction	NOUN
dti-2574	27	26	(	(	PUNCT
dti-2574	27	27	10	10	NUM
dti-2574	27	28	)	)	PUNCT
dti-2574	27	29	.	.	PUNCT
dti-2574	28	1	skeletal	skeletal	ADJ
dti-2574	28	2	muscle	muscle	NOUN
dti-2574	28	3	is	be	AUX
dti-2574	28	4	one	one	NUM
dti-2574	28	5	of	of	ADP
dti-2574	28	6	the	the	DET
dti-2574	28	7	most	most	ADV
dti-2574	28	8	significant	significant	ADJ
dti-2574	28	9	muscle	muscle	NOUN
dti-2574	28	10	tissues	tissue	NOUN
dti-2574	28	11	in	in	ADP
dti-2574	28	12	the	the	DET
dti-2574	28	13	body	body	NOUN
dti-2574	28	14	.	.	PUNCT
dti-2574	29	1	thousands	thousand	NOUN
dti-2574	29	2	of	of	ADP
dti-2574	29	3	muscle	muscle	NOUN
dti-2574	29	4	fibers	fiber	NOUN
dti-2574	29	5	are	be	AUX
dti-2574	29	6	encased	encased	ADJ
dti-2574	29	7	in	in	ADP
dti-2574	29	8	connective	connective	ADJ
dti-2574	29	9	tissue	tissue	NOUN
dti-2574	29	10	sheaths	sheath	NOUN
dti-2574	29	11	to	to	PART
dti-2574	29	12	form	form	VERB
dti-2574	29	13	each	each	DET
dti-2574	29	14	skeletal	skeletal	ADJ
dti-2574	29	15	muscle	muscle	NOUN
dti-2574	29	16	.	.	PUNCT
dti-2574	30	1	the	the	DET
dti-2574	30	2	size	size	NOUN
dti-2574	30	3	of	of	ADP
dti-2574	30	4	skeletal	skeletal	ADJ
dti-2574	30	5	muscle	muscle	NOUN
dti-2574	30	6	fiber	fiber	NOUN
dti-2574	30	7	is	be	AUX
dti-2574	30	8	dependent	dependent	ADJ
dti-2574	30	9	on	on	ADP
dti-2574	30	10	the	the	DET
dti-2574	30	11	balance	balance	NOUN
dti-2574	30	12	between	between	ADP
dti-2574	30	13	the	the	DET
dti-2574	30	14	protein	protein	NOUN
dti-2574	30	15	synthesis	synthesis	NOUN
dti-2574	30	16	and	and	CCONJ
dti-2574	30	17	protein	protein	NOUN
dti-2574	30	18	degradation	degradation	NOUN
dti-2574	30	19	(	(	PUNCT
dti-2574	30	20	11,12	11,12	NOUN
dti-2574	30	21	)	)	PUNCT
dti-2574	30	22	.	.	PUNCT
dti-2574	31	1	animal	animal	NOUN
dti-2574	31	2	studies	study	NOUN
dti-2574	31	3	have	have	AUX
dti-2574	31	4	demonstrated	demonstrate	VERB
dti-2574	31	5	that	that	SCONJ
dti-2574	31	6	protein	protein	NOUN
dti-2574	31	7	synthesis	synthesis	NOUN
dti-2574	31	8	declines	decline	VERB
dti-2574	31	9	rapidly	rapidly	ADV
dti-2574	31	10	within	within	ADP
dti-2574	31	11	the	the	DET
dti-2574	31	12	first	first	ADJ
dti-2574	31	13	6	6	NUM
dti-2574	31	14	hours	hour	NOUN
dti-2574	31	15	of	of	ADP
dti-2574	31	16	mv	mv	PROPN
dti-2574	31	17	and	and	CCONJ
dti-2574	31	18	remains	remain	VERB
dti-2574	31	19	depressed	depressed	ADJ
dti-2574	31	20	during	during	ADP
dti-2574	31	21	the	the	DET
dti-2574	31	22	next	next	ADJ
dti-2574	31	23	12	12	NUM
dti-2574	31	24	hours	hour	NOUN
dti-2574	31	25	(	(	PUNCT
dti-2574	31	26	11	11	NUM
dti-2574	31	27	)	)	PUNCT
dti-2574	31	28	.	.	PUNCT
dti-2574	32	1	at	at	ADP
dti-2574	32	2	the	the	DET
dti-2574	32	3	same	same	ADJ
dti-2574	32	4	time	time	NOUN
dti-2574	32	5	,	,	PUNCT
dti-2574	32	6	the	the	DET
dti-2574	32	7	prolonged	prolonged	ADJ
dti-2574	32	8	mv	mv	PROPN
dti-2574	32	9	increases	increase	VERB
dti-2574	32	10	the	the	DET
dti-2574	32	11	activity	activity	NOUN
dti-2574	32	12	of	of	ADP
dti-2574	32	13	all	all	DET
dti-2574	32	14	major	major	ADJ
dti-2574	32	15	proteolytic	proteolytic	ADJ
dti-2574	32	16	systems	system	NOUN
dti-2574	32	17	:	:	PUNCT
dti-2574	32	18	macroautophagy	macroautophagy	ADJ
dti-2574	32	19	,	,	PUNCT
dti-2574	32	20	calpains	calpain	NOUN
dti-2574	32	21	,	,	PUNCT
dti-2574	32	22	caspases	caspase	NOUN
dti-2574	32	23	and	and	CCONJ
dti-2574	32	24	the	the	DET
dti-2574	32	25	ubiquitin	ubiquitin	ADJ
dti-2574	32	26	-	-	PUNCT
dti-2574	32	27	proteasome	proteasome	NOUN
dti-2574	32	28	systems	system	NOUN
dti-2574	32	29	.	.	PUNCT
dti-2574	33	1	moreover	moreover	ADV
dti-2574	33	2	prolonged	prolong	VERB
dti-2574	33	3	mv	mv	PROPN
dti-2574	33	4	results	result	NOUN
dti-2574	33	5	in	in	ADP
dti-2574	33	6	oxidative	oxidative	ADJ
dti-2574	33	7	damage	damage	NOUN
dti-2574	33	8	to	to	ADP
dti-2574	33	9	the	the	DET
dti-2574	33	10	diaphragm	diaphragm	NOUN
dti-2574	33	11	–	–	PUNCT
dti-2574	33	12	reactive	reactive	ADJ
dti-2574	33	13	oxygen	oxygen	NOUN
dti-2574	33	14	species	specie	NOUN
dti-2574	33	15	and	and	CCONJ
dti-2574	33	16	their	their	PRON
dti-2574	33	17	derivatives	derivative	NOUN
dti-2574	33	18	have	have	VERB
dti-2574	33	19	a	a	DET
dti-2574	33	20	significant	significant	ADJ
dti-2574	33	21	impact	impact	NOUN
dti-2574	33	22	on	on	ADP
dti-2574	33	23	skeletal	skeletal	ADJ
dti-2574	33	24	muscle	muscle	NOUN
dti-2574	33	25	contractile	contractile	NOUN
dti-2574	33	26	function	function	NOUN
dti-2574	33	27	(	(	PUNCT
dti-2574	33	28	13	13	NUM
dti-2574	33	29	)	)	PUNCT
dti-2574	33	30	.	.	PUNCT
dti-2574	34	1	prolonged	prolong	VERB
dti-2574	34	2	mv	mv	PROPN
dti-2574	34	3	results	result	NOUN
dti-2574	34	4	in	in	ADP
dti-2574	34	5	less	less	ADV
dti-2574	34	6	efficient	efficient	ADJ
dti-2574	34	7	calcium	calcium	NOUN
dti-2574	34	8	activation	activation	NOUN
dti-2574	34	9	of	of	ADP
dti-2574	34	10	diaphragm	diaphragm	NOUN
dti-2574	34	11	fibers	fiber	NOUN
dti-2574	34	12	most	most	ADV
dti-2574	34	13	likely	likely	ADJ
dti-2574	34	14	due	due	ADJ
dti-2574	34	15	to	to	ADP
dti-2574	34	16	oxidative	oxidative	ADJ
dti-2574	34	17	modification	modification	NOUN
dti-2574	34	18	of	of	ADP
dti-2574	34	19	diaphragm	diaphragm	NOUN
dti-2574	34	20	contractile	contractile	NOUN
dti-2574	34	21	proteins	protein	NOUN
dti-2574	34	22	(	(	PUNCT
dti-2574	34	23	14	14	NUM
dti-2574	34	24	)	)	PUNCT
dti-2574	34	25	.	.	PUNCT
dti-2574	35	1	levosimendan	levosimendan	PROPN
dti-2574	35	2	is	be	AUX
dti-2574	35	3	a	a	DET
dti-2574	35	4	calcium	calcium	NOUN
dti-2574	35	5	sensitizer	sensitizer	NOUN
dti-2574	35	6	,	,	PUNCT
dti-2574	35	7	first	first	ADV
dti-2574	35	8	described	describe	VERB
dti-2574	35	9	in	in	ADP
dti-2574	35	10	1995	1995	NUM
dti-2574	35	11	,	,	PUNCT
dti-2574	35	12	that	that	PRON
dti-2574	35	13	is	be	AUX
dti-2574	35	14	administered	administer	VERB
dti-2574	35	15	to	to	PART
dti-2574	35	16	enhance	enhance	VERB
dti-2574	35	17	cardiac	cardiac	ADJ
dti-2574	35	18	contractility	contractility	NOUN
dti-2574	35	19	in	in	ADP
dti-2574	35	20	patients	patient	NOUN
dti-2574	35	21	with	with	ADP
dti-2574	35	22	acute	acute	ADJ
dti-2574	35	23	heart	heart	NOUN
dti-2574	35	24	failure	failure	NOUN
dti-2574	35	25	(	(	PUNCT
dti-2574	35	26	15,16	15,16	NUM
dti-2574	35	27	)	)	PUNCT
dti-2574	35	28	.	.	PUNCT
dti-2574	36	1	in	in	ADP
dti-2574	36	2	addition	addition	NOUN
dti-2574	36	3	,	,	PUNCT
dti-2574	36	4	levosimendan	levosimendan	PROPN
dti-2574	36	5	improves	improve	VERB
dti-2574	36	6	respiratory	respiratory	ADJ
dti-2574	36	7	muscle	muscle	NOUN
dti-2574	36	8	function	function	NOUN
dti-2574	36	9	in	in	ADP
dti-2574	36	10	healthy	healthy	ADJ
dti-2574	36	11	subjects	subject	NOUN
dti-2574	36	12	and	and	CCONJ
dti-2574	36	13	patients	patient	NOUN
dti-2574	36	14	with	with	ADP
dti-2574	36	15	chronic	chronic	ADJ
dti-2574	36	16	obstructive	obstructive	ADJ
dti-2574	36	17	pulmonary	pulmonary	ADJ
dti-2574	36	18	disease	disease	NOUN
dti-2574	36	19	(	(	PUNCT
dti-2574	36	20	copd	copd	NOUN
dti-2574	36	21	)	)	PUNCT
dti-2574	36	22	(	(	PUNCT
dti-2574	36	23	17	17	NUM
dti-2574	36	24	)	)	PUNCT
dti-2574	36	25	,	,	PUNCT
dti-2574	36	26	through	through	ADP
dti-2574	36	27	the	the	DET
dti-2574	36	28	improvement	improvement	NOUN
dti-2574	36	29	of	of	ADP
dti-2574	36	30	calcium	calcium	NOUN
dti-2574	36	31	sensitization	sensitization	NOUN
dti-2574	36	32	of	of	ADP
dti-2574	36	33	the	the	DET
dti-2574	36	34	contractile	contractile	NOUN
dti-2574	36	35	proteins	protein	NOUN
dti-2574	36	36	(	(	PUNCT
dti-2574	36	37	18	18	NUM
dti-2574	36	38	)	)	PUNCT
dti-2574	36	39	.	.	PUNCT
dti-2574	37	1	moreover	moreover	ADV
dti-2574	37	2	,	,	PUNCT
dti-2574	37	3	it	it	PRON
dti-2574	37	4	reduces	reduce	VERB
dti-2574	37	5	inflammation	inflammation	NOUN
dti-2574	37	6	and	and	CCONJ
dti-2574	37	7	oxidative	oxidative	ADJ
dti-2574	37	8	stress	stress	NOUN
dti-2574	37	9	(	(	PUNCT
dti-2574	37	10	19	19	NUM
dti-2574	37	11	)	)	PUNCT
dti-2574	37	12	.	.	PUNCT
dti-2574	38	1	a	a	DET
dti-2574	38	2	recent	recent	ADJ
dti-2574	38	3	study	study	NOUN
dti-2574	38	4	also	also	ADV
dti-2574	38	5	demonstrated	demonstrate	VERB
dti-2574	38	6	that	that	SCONJ
dti-2574	38	7	levosimendan	levosimendan	PROPN
dti-2574	38	8	dampens	dampen	VERB
dti-2574	38	9	nitrosative	nitrosative	ADJ
dti-2574	38	10	stress	stress	NOUN
dti-2574	38	11	in	in	ADP
dti-2574	38	12	the	the	DET
dti-2574	38	13	diaphragm	diaphragm	NOUN
dti-2574	38	14	of	of	ADP
dti-2574	38	15	mechanically	mechanically	ADV
dti-2574	38	16	ventilated	ventilate	VERB
dti-2574	38	17	endotoxemic	endotoxemic	ADJ
dti-2574	38	18	mice	mouse	NOUN
dti-2574	38	19	(	(	PUNCT
dti-2574	38	20	20	20	NUM
dti-2574	38	21	)	)	PUNCT
dti-2574	38	22	.	.	PUNCT
dti-2574	39	1	thus	thus	ADV
dti-2574	39	2	,	,	PUNCT
dti-2574	39	3	we	we	PRON
dti-2574	39	4	administered	administer	VERB
dti-2574	39	5	levosimendan	levosimendan	PROPN
dti-2574	39	6	to	to	ADP
dti-2574	39	7	an	an	DET
dti-2574	39	8	in	in	ADP
dti-2574	39	9	vivo	vivo	NOUN
dti-2574	39	10	model	model	NOUN
dti-2574	39	11	of	of	ADP
dti-2574	39	12	vidd	vidd	NOUN
dti-2574	39	13	to	to	PART
dti-2574	39	14	determine	determine	VERB
dti-2574	39	15	if	if	SCONJ
dti-2574	39	16	it	it	PRON
dti-2574	39	17	could	could	AUX
dti-2574	39	18	alleviate	alleviate	VERB
dti-2574	39	19	the	the	DET
dti-2574	39	20	negative	negative	ADJ
dti-2574	39	21	impacts	impact	NOUN
dti-2574	39	22	of	of	ADP
dti-2574	39	23	mv	mv	PROPN
dti-2574	39	24	.	.	PUNCT
dti-2574	40	1	therapeutic	therapeutic	ADJ
dti-2574	40	2	effects	effect	NOUN
dti-2574	40	3	were	be	AUX
dti-2574	40	4	determined	determine	VERB
dti-2574	40	5	by	by	ADP
dti-2574	40	6	measuring	measure	VERB
dti-2574	40	7	muscle	muscle	NOUN
dti-2574	40	8	contraction	contraction	NOUN
dti-2574	40	9	and	and	CCONJ
dti-2574	40	10	diaphragm	diaphragm	NOUN
dti-2574	40	11	muscle	muscle	NOUN
dti-2574	40	12	viability	viability	NOUN
dti-2574	40	13	.	.	PUNCT
dti-2574	41	1	the	the	DET
dti-2574	41	2	aim	aim	NOUN
dti-2574	41	3	of	of	ADP
dti-2574	41	4	the	the	DET
dti-2574	41	5	study	study	NOUN
dti-2574	41	6	was	be	AUX
dti-2574	41	7	to	to	PART
dti-2574	41	8	evaluate	evaluate	VERB
dti-2574	41	9	the	the	DET
dti-2574	41	10	effect	effect	NOUN
dti-2574	41	11	of	of	ADP
dti-2574	41	12	the	the	DET
dti-2574	41	13	treatment	treatment	NOUN
dti-2574	41	14	of	of	ADP
dti-2574	41	15	levosimendan	levosimendan	PROPN
dti-2574	41	16	in	in	ADP
dti-2574	41	17	a	a	DET
dti-2574	41	18	rat	rat	NOUN
dti-2574	41	19	model	model	NOUN
dti-2574	41	20	on	on	ADP
dti-2574	41	21	vidd	vidd	NOUN
dti-2574	41	22	on	on	ADP
dti-2574	41	23	:	:	PUNCT
dti-2574	41	24	1	1	X
dti-2574	41	25	.	.	X
dti-2574	42	1	the	the	DET
dti-2574	42	2	preservation	preservation	NOUN
dti-2574	42	3	of	of	ADP
dti-2574	42	4	diaphragm	diaphragm	NOUN
dti-2574	42	5	muscle	muscle	NOUN
dti-2574	42	6	structure	structure	NOUN
dti-2574	42	7	;	;	PUNCT
dti-2574	42	8	2	2	X
dti-2574	42	9	.	.	X
dti-2574	42	10	the	the	DET
dti-2574	42	11	level	level	NOUN
dti-2574	42	12	of	of	ADP
dti-2574	42	13	autophagy	autophagy	ADJ
dti-2574	42	14	activation	activation	NOUN
dti-2574	42	15	in	in	ADP
dti-2574	42	16	the	the	DET
dti-2574	42	17	diaphragm	diaphragm	NOUN
dti-2574	42	18	;	;	PUNCT
dti-2574	42	19	3	3	X
dti-2574	42	20	.	.	X
dti-2574	43	1	the	the	DET
dti-2574	43	2	diaphragm	diaphragm	NOUN
dti-2574	43	3	muscular	muscular	ADJ
dti-2574	43	4	contractile	contractile	NOUN
dti-2574	43	5	function	function	NOUN
dti-2574	43	6	.	.	PUNCT
dti-2574	44	1	materials	material	NOUN
dti-2574	44	2	and	and	CCONJ
dti-2574	44	3	methods	method	NOUN
dti-2574	44	4	animals	animal	NOUN
dti-2574	44	5	male	male	ADJ
dti-2574	44	6	sprague	sprague	NOUN
dti-2574	44	7	-	-	PUNCT
dti-2574	44	8	dawley	dawley	NOUN
dti-2574	44	9	rats	rat	NOUN
dti-2574	44	10	(	(	PUNCT
dti-2574	44	11	250	250	NUM
dti-2574	44	12	-	-	SYM
dti-2574	44	13	300	300	NUM
dti-2574	44	14	g	g	NOUN
dti-2574	44	15	;	;	PUNCT
dti-2574	44	16	envigo	envigo	PROPN
dti-2574	44	17	rms	rm	NOUN
dti-2574	44	18	s.r.l	s.r.l	NOUN
dti-2574	44	19	.	.	PROPN
dti-2574	44	20	,	,	PUNCT
dti-2574	44	21	udine	udine	PROPN
dti-2574	44	22	,	,	PUNCT
dti-2574	44	23	italy	italy	PROPN
dti-2574	44	24	)	)	PUNCT
dti-2574	44	25	were	be	AUX
dti-2574	44	26	used	use	VERB
dti-2574	44	27	in	in	ADP
dti-2574	44	28	this	this	DET
dti-2574	44	29	study	study	NOUN
dti-2574	44	30	.	.	PUNCT
dti-2574	45	1	animals	animal	NOUN
dti-2574	45	2	were	be	AUX
dti-2574	45	3	housed	house	VERB
dti-2574	45	4	two	two	NUM
dti-2574	45	5	per	per	ADP
dti-2574	45	6	cage	cage	NOUN
dti-2574	45	7	in	in	ADP
dti-2574	45	8	a	a	DET
dti-2574	45	9	limited	limited	ADJ
dti-2574	45	10	access	access	NOUN
dti-2574	45	11	animal	animal	NOUN
dti-2574	45	12	facility	facility	NOUN
dti-2574	45	13	,	,	PUNCT
dti-2574	45	14	with	with	ADP
dti-2574	45	15	the	the	DET
dti-2574	45	16	room	room	NOUN
dti-2574	45	17	temperature	temperature	NOUN
dti-2574	45	18	at	at	ADP
dti-2574	45	19	20	20	NUM
dti-2574	45	20	±	±	NUM
dti-2574	45	21	2	2	NUM
dti-2574	45	22	°	°	ADP
dti-2574	45	23	c	c	NOUN
dti-2574	45	24	and	and	CCONJ
dti-2574	45	25	the	the	DET
dti-2574	45	26	relative	relative	ADJ
dti-2574	45	27	humidity	humidity	NOUN
dti-2574	45	28	set	set	VERB
dti-2574	45	29	at	at	ADP
dti-2574	45	30	55	55	NUM
dti-2574	45	31	±	±	NUM
dti-2574	45	32	10	10	NUM
dti-2574	45	33	%	%	NOUN
dti-2574	45	34	.	.	PUNCT
dti-2574	46	1	artificial	artificial	ADJ
dti-2574	46	2	lighting	lighting	NOUN
dti-2574	46	3	provided	provide	VERB
dti-2574	46	4	a	a	DET
dti-2574	46	5	12	12	NUM
dti-2574	46	6	-	-	PUNCT
dti-2574	46	7	hour	hour	NOUN
dti-2574	46	8	light/12	light/12	ADJ
dti-2574	46	9	-	-	PUNCT
dti-2574	46	10	hour	hour	NOUN
dti-2574	46	11	dark	dark	NOUN
dti-2574	46	12	(	(	PUNCT
dti-2574	46	13	7	7	NUM
dti-2574	46	14	am.–7	am.–7	ADP
dti-2574	46	15	pm	pm	NOUN
dti-2574	46	16	)	)	PUNCT
dti-2574	46	17	cycle	cycle	NOUN
dti-2574	46	18	.	.	PUNCT
dti-2574	47	1	the	the	DET
dti-2574	47	2	general	general	ADJ
dti-2574	47	3	condition	condition	NOUN
dti-2574	47	4	of	of	ADP
dti-2574	47	5	the	the	DET
dti-2574	47	6	animals	animal	NOUN
dti-2574	47	7	before	before	SCONJ
dti-2574	47	8	the	the	DET
dti-2574	47	9	experiment	experiment	NOUN
dti-2574	47	10	was	be	AUX
dti-2574	47	11	assessed	assess	VERB
dti-2574	47	12	daily	daily	ADV
dti-2574	47	13	.	.	PUNCT
dti-2574	48	1	the	the	DET
dti-2574	48	2	care	care	NOUN
dti-2574	48	3	and	and	CCONJ
dti-2574	48	4	husbandry	husbandry	NOUN
dti-2574	48	5	of	of	ADP
dti-2574	48	6	animals	animal	NOUN
dti-2574	48	7	were	be	AUX
dti-2574	48	8	in	in	ADP
dti-2574	48	9	conformity	conformity	NOUN
dti-2574	48	10	with	with	ADP
dti-2574	48	11	the	the	DET
dti-2574	48	12	institutional	institutional	ADJ
dti-2574	48	13	guidelines	guideline	NOUN
dti-2574	48	14	in	in	ADP
dti-2574	48	15	compliance	compliance	NOUN
dti-2574	48	16	with	with	ADP
dti-2574	48	17	italian	italian	ADJ
dti-2574	48	18	and	and	CCONJ
dti-2574	48	19	european	european	ADJ
dti-2574	48	20	laws	law	NOUN
dti-2574	48	21	and	and	CCONJ
dti-2574	48	22	policies	policy	NOUN
dti-2574	48	23	.	.	PUNCT
dti-2574	49	1	the	the	DET
dti-2574	49	2	animal	animal	NOUN
dti-2574	49	3	study	study	NOUN
dti-2574	49	4	was	be	AUX
dti-2574	49	5	reviewed	review	VERB
dti-2574	49	6	and	and	CCONJ
dti-2574	49	7	approved	approve	VERB
dti-2574	49	8	by	by	ADP
dti-2574	49	9	the	the	DET
dti-2574	49	10	italian	italian	PROPN
dti-2574	49	11	ministry	ministry	PROPN
dti-2574	49	12	of	of	ADP
dti-2574	49	13	health	health	PROPN
dti-2574	49	14	(	(	PUNCT
dti-2574	49	15	773/2018	773/2018	NUM
dti-2574	49	16	-	-	PUNCT
dti-2574	49	17	pr	pr	NOUN
dti-2574	49	18	)	)	PUNCT
dti-2574	49	19	and	and	CCONJ
dti-2574	49	20	by	by	ADP
dti-2574	49	21	the	the	DET
dti-2574	49	22	animal	animal	NOUN
dti-2574	49	23	care	care	NOUN
dti-2574	49	24	unit	unit	NOUN
dti-2574	49	25	of	of	ADP
dti-2574	49	26	the	the	DET
dti-2574	49	27	university	university	PROPN
dti-2574	49	28	of	of	ADP
dti-2574	49	29	milano	milano	PROPN
dti-2574	49	30	-	-	PUNCT
dti-2574	49	31	bicocca	bicocca	PROPN
dti-2574	49	32	,	,	PUNCT
dti-2574	49	33	monza	monza	PROPN
dti-2574	49	34	,	,	PUNCT
dti-2574	49	35	italy	italy	PROPN
dti-2574	49	36	.	.	PUNCT
dti-2574	50	1	in	in	ADP
dti-2574	50	2	full	full	ADJ
dti-2574	50	3	respect	respect	NOUN
dti-2574	50	4	of	of	ADP
dti-2574	50	5	the	the	DET
dti-2574	50	6	reduction	reduction	NOUN
dti-2574	50	7	principle	principle	NOUN
dti-2574	50	8	of	of	ADP
dti-2574	50	9	the	the	DET
dti-2574	50	10	3rs	3rs	NOUN
dti-2574	50	11	(	(	PUNCT
dti-2574	50	12	21	21	NUM
dti-2574	50	13	)	)	PUNCT
dti-2574	50	14	,	,	PUNCT
dti-2574	50	15	the	the	DET
dti-2574	50	16	number	number	NOUN
dti-2574	50	17	of	of	ADP
dti-2574	50	18	animals	animal	NOUN
dti-2574	50	19	/	/	SYM
dti-2574	50	20	groups	group	NOUN
dti-2574	50	21	was	be	AUX
dti-2574	50	22	selected	select	VERB
dti-2574	50	23	to	to	PART
dti-2574	50	24	obtain	obtain	VERB
dti-2574	50	25	reliable	reliable	ADJ
dti-2574	50	26	results	result	NOUN
dti-2574	50	27	and	and	CCONJ
dti-2574	50	28	enough	enough	ADJ
dti-2574	50	29	biological	biological	ADJ
dti-2574	50	30	samples	sample	NOUN
dti-2574	50	31	to	to	PART
dti-2574	50	32	perform	perform	VERB
dti-2574	50	33	the	the	DET
dti-2574	50	34	analysis	analysis	NOUN
dti-2574	50	35	planned	plan	VERB
dti-2574	50	36	.	.	PUNCT
dti-2574	51	1	experimental	experimental	ADJ
dti-2574	51	2	protocol	protocol	NOUN
dti-2574	51	3	the	the	DET
dti-2574	51	4	experimental	experimental	ADJ
dti-2574	51	5	design	design	NOUN
dti-2574	51	6	is	be	AUX
dti-2574	51	7	composed	compose	VERB
dti-2574	51	8	of	of	ADP
dti-2574	51	9	three	three	NUM
dti-2574	51	10	experimental	experimental	ADJ
dti-2574	51	11	group	group	NOUN
dti-2574	51	12	of	of	ADP
dti-2574	51	13	rats	rat	NOUN
dti-2574	51	14	:	:	PUNCT
dti-2574	51	15	–	–	PUNCT
dti-2574	51	16	healthy	healthy	ADJ
dti-2574	51	17	:	:	PUNCT
dti-2574	51	18	non	non	ADJ
dti-2574	51	19	-	-	ADJ
dti-2574	51	20	anesthetized	anesthetized	ADJ
dti-2574	51	21	and	and	CCONJ
dti-2574	51	22	spontaneously	spontaneously	ADV
dti-2574	51	23	breathing	breathe	VERB
dti-2574	51	24	rats	rat	NOUN
dti-2574	51	25	;	;	PUNCT
dti-2574	51	26	–	–	PUNCT
dti-2574	51	27	vidd	vidd	NOUN
dti-2574	51	28	:	:	PUNCT
dti-2574	51	29	anesthetized	anesthetized	ADJ
dti-2574	51	30	and	and	CCONJ
dti-2574	51	31	mechanically	mechanically	ADV
dti-2574	51	32	ventilated	ventilate	VERB
dti-2574	51	33	rats	rat	NOUN
dti-2574	51	34	without	without	ADP
dti-2574	51	35	any	any	DET
dti-2574	51	36	pharmacological	pharmacological	ADJ
dti-2574	51	37	treatment	treatment	NOUN
dti-2574	51	38	;	;	PUNCT
dti-2574	51	39	–	–	PUNCT
dti-2574	51	40	vidd+levo	vidd+levo	NOUN
dti-2574	51	41	:	:	PUNCT
dti-2574	51	42	anesthetized	anesthetized	ADJ
dti-2574	51	43	and	and	CCONJ
dti-2574	51	44	ventilated	ventilate	VERB
dti-2574	51	45	rats	rat	NOUN
dti-2574	51	46	with	with	ADP
dti-2574	51	47	levosimendan	levosimendan	PROPN
dti-2574	51	48	infusion	infusion	NOUN
dti-2574	51	49	.	.	PUNCT
dti-2574	52	1	rats	rat	NOUN
dti-2574	52	2	were	be	AUX
dti-2574	52	3	anesthetized	anesthetize	VERB
dti-2574	52	4	with	with	ADP
dti-2574	52	5	ketamine	ketamine	PROPN
dti-2574	52	6	(	(	PUNCT
dti-2574	52	7	100	100	NUM
dti-2574	52	8	mg	mg	PROPN
dti-2574	52	9	/	/	SYM
dti-2574	52	10	kg	kg	NOUN
dti-2574	52	11	)	)	PUNCT
dti-2574	52	12	and	and	CCONJ
dti-2574	52	13	xylazine	xylazine	NOUN
dti-2574	52	14	(	(	PUNCT
dti-2574	52	15	4	4	NUM
dti-2574	52	16	mg	mg	NUM
dti-2574	52	17	/	/	SYM
dti-2574	52	18	kg	kg	PROPN
dti-2574	52	19	)	)	PUNCT
dti-2574	52	20	,	,	PUNCT
dti-2574	52	21	orotracheally	orotracheally	ADV
dti-2574	52	22	intubated	intubate	VERB
dti-2574	52	23	and	and	CCONJ
dti-2574	52	24	ventilated	ventilate	VERB
dti-2574	52	25	for	for	ADP
dti-2574	52	26	5	5	NUM
dti-2574	52	27	hours	hour	NOUN
dti-2574	52	28	(	(	PUNCT
dti-2574	52	29	harvard	harvard	PROPN
dti-2574	52	30	inspira	inspira	PROPN
dti-2574	52	31	;	;	PUNCT
dti-2574	52	32	tidal	tidal	ADJ
dti-2574	52	33	volume	volume	NOUN
dti-2574	52	34	:	:	PUNCT
dti-2574	52	35	10	10	NUM
dti-2574	52	36	ml	ml	NOUN
dti-2574	52	37	/	/	SYM
dti-2574	52	38	kg	kg	PROPN
dti-2574	52	39	;	;	PUNCT
dti-2574	52	40	respiratory	respiratory	ADJ
dti-2574	52	41	rate	rate	NOUN
dti-2574	52	42	:	:	PUNCT
dti-2574	52	43	80	80	NUM
dti-2574	52	44	/	/	SYM
dti-2574	52	45	min	min	NOUN
dti-2574	52	46	;	;	PUNCT
dti-2574	52	47	positive	positive	ADJ
dti-2574	52	48	end	end	NOUN
dti-2574	52	49	-	-	PUNCT
dti-2574	52	50	expiratory	expiratory	NOUN
dti-2574	52	51	pressure	pressure	NOUN
dti-2574	53	1	[	[	X
dti-2574	53	2	peep	peep	NOUN
dti-2574	53	3	]	]	X
dti-2574	53	4	:	:	PUNCT
dti-2574	53	5	2	2	NUM
dti-2574	53	6	-	-	SYM
dti-2574	53	7	2.5	2.5	NUM
dti-2574	53	8	cmh2o	cmh2o	NOUN
dti-2574	53	9	;	;	PUNCT
dti-2574	53	10	fraction	fraction	NOUN
dti-2574	53	11	of	of	ADP
dti-2574	53	12	inspired	inspire	VERB
dti-2574	53	13	oxygen	oxygen	NOUN
dti-2574	54	1	[	[	X
dti-2574	54	2	fio2	fio2	NOUN
dti-2574	54	3	:	:	PUNCT
dti-2574	54	4	0.5	0.5	NUM
dti-2574	54	5	]	]	NUM
dti-2574	54	6	)	)	PUNCT
dti-2574	54	7	.	.	PUNCT
dti-2574	55	1	anesthesia	anesthesia	PROPN
dti-2574	55	2	and	and	CCONJ
dti-2574	55	3	paralysis	paralysis	NOUN
dti-2574	55	4	were	be	AUX
dti-2574	55	5	maintained	maintain	VERB
dti-2574	55	6	throughout	throughout	ADP
dti-2574	55	7	the	the	DET
dti-2574	55	8	experiment	experiment	NOUN
dti-2574	55	9	by	by	ADP
dti-2574	55	10	infusion	infusion	NOUN
dti-2574	55	11	in	in	ADP
dti-2574	55	12	the	the	DET
dti-2574	55	13	right	right	ADJ
dti-2574	55	14	femoral	femoral	ADJ
dti-2574	55	15	artery	artery	NOUN
dti-2574	55	16	of	of	ADP
dti-2574	55	17	propofol	propofol	NOUN
dti-2574	55	18	(	(	PUNCT
dti-2574	55	19	13	13	NUM
dti-2574	55	20	mg/	mg/	NOUN
dti-2574	55	21	kg	kg	PROPN
dti-2574	55	22	/	/	SYM
dti-2574	55	23	h	h	NOUN
dti-2574	55	24	)	)	PUNCT
dti-2574	55	25	and	and	CCONJ
dti-2574	55	26	ketamine	ketamine	PROPN
dti-2574	55	27	(	(	PUNCT
dti-2574	55	28	5	5	NUM
dti-2574	55	29	mg	mg	PROPN
dti-2574	55	30	/	/	SYM
dti-2574	55	31	kg	kg	PROPN
dti-2574	55	32	/	/	SYM
dti-2574	55	33	h	h	NOUN
dti-2574	55	34	)	)	PUNCT
dti-2574	55	35	and	and	CCONJ
dti-2574	55	36	in	in	ADP
dti-2574	55	37	the	the	DET
dti-2574	55	38	right	right	ADJ
dti-2574	55	39	jugular	jugular	PROPN
dti-2574	55	40	vein	vein	NOUN
dti-2574	55	41	of	of	ADP
dti-2574	55	42	rocuronium	rocuronium	NOUN
dti-2574	55	43	bromide	bromide	NOUN
dti-2574	55	44	(	(	PUNCT
dti-2574	55	45	1.5	1.5	NUM
dti-2574	55	46	mg	mg	PROPN
dti-2574	55	47	/	/	SYM
dti-2574	55	48	kg	kg	PROPN
dti-2574	55	49	/	/	SYM
dti-2574	55	50	h	h	NOUN
dti-2574	55	51	)	)	PUNCT
dti-2574	55	52	and	and	CCONJ
dti-2574	55	53	ringer	ringer	NOUN
dti-2574	55	54	acetate	acetate	NOUN
dti-2574	55	55	(	(	PUNCT
dti-2574	55	56	1.8	1.8	NUM
dti-2574	55	57	ml	ml	NOUN
dti-2574	55	58	/	/	SYM
dti-2574	55	59	h	h	NOUN
dti-2574	55	60	)	)	PUNCT
dti-2574	55	61	.	.	PUNCT
dti-2574	56	1	airway	airway	NOUN
dti-2574	56	2	pressure	pressure	NOUN
dti-2574	56	3	and	and	CCONJ
dti-2574	56	4	hemodynamic	hemodynamic	ADJ
dti-2574	56	5	parameters	parameter	NOUN
dti-2574	56	6	were	be	AUX
dti-2574	56	7	monitored	monitor	VERB
dti-2574	56	8	through	through	ADP
dti-2574	56	9	pressure	pressure	NOUN
dti-2574	56	10	transducers	transducer	NOUN
dti-2574	56	11	in	in	ADP
dti-2574	56	12	ventilator	ventilator	NOUN
dti-2574	56	13	and	and	CCONJ
dti-2574	56	14	at	at	ADP
dti-2574	56	15	the	the	DET
dti-2574	56	16	arterial	arterial	ADJ
dti-2574	56	17	catheter	catheter	NOUN
dti-2574	56	18	.	.	PUNCT
dti-2574	57	1	a	a	DET
dti-2574	57	2	recruitment	recruitment	NOUN
dti-2574	57	3	maneuver	maneuver	NOUN
dti-2574	57	4	(	(	PUNCT
dti-2574	57	5	30	30	NUM
dti-2574	57	6	cmh2o	cmh2o	X
dti-2574	57	7	for	for	ADP
dti-2574	57	8	10	10	NUM
dti-2574	57	9	sec	sec	PROPN
dti-2574	57	10	)	)	PUNCT
dti-2574	57	11	was	be	AUX
dti-2574	57	12	performed	perform	VERB
dti-2574	57	13	every	every	DET
dti-2574	57	14	60	60	NUM
dti-2574	57	15	minutes	minute	NOUN
dti-2574	57	16	,	,	PUNCT
dti-2574	57	17	being	be	AUX
dti-2574	57	18	the	the	DET
dti-2574	57	19	plateau	plateau	NOUN
dti-2574	57	20	pressure	pressure	NOUN
dti-2574	57	21	,	,	PUNCT
dti-2574	57	22	and	and	CCONJ
dti-2574	57	23	respiratory	respiratory	ADJ
dti-2574	57	24	system	system	NOUN
dti-2574	57	25	static	static	ADJ
dti-2574	57	26	compliance	compliance	NOUN
dti-2574	57	27	was	be	AUX
dti-2574	57	28	measured	measure	VERB
dti-2574	57	29	every	every	DET
dti-2574	57	30	hour	hour	NOUN
dti-2574	57	31	.	.	PUNCT
dti-2574	58	1	rats	rat	NOUN
dti-2574	58	2	belonging	belong	VERB
dti-2574	58	3	to	to	ADP
dti-2574	58	4	the	the	DET
dti-2574	58	5	treatment	treatment	NOUN
dti-2574	58	6	group	group	NOUN
dti-2574	58	7	(	(	PUNCT
dti-2574	58	8	vidd+levo	vidd+levo	PROPN
dti-2574	58	9	)	)	PUNCT
dti-2574	58	10	received	receive	VERB
dti-2574	58	11	a	a	DET
dti-2574	58	12	dose	dose	NOUN
dti-2574	58	13	(	(	PUNCT
dti-2574	58	14	24	24	NUM
dti-2574	58	15	µg	µg	NOUN
dti-2574	58	16	/	/	SYM
dti-2574	58	17	kg	kg	NOUN
dti-2574	58	18	)	)	PUNCT
dti-2574	58	19	of	of	ADP
dti-2574	58	20	levosimendan	levosimendan	PROPN
dti-2574	58	21	(	(	PUNCT
dti-2574	58	22	simdax	simdax	PROPN
dti-2574	58	23	;	;	PUNCT
dti-2574	58	24	orion	orion	PROPN
dti-2574	58	25	pharma	pharma	PROPN
dti-2574	58	26	)	)	PUNCT
dti-2574	58	27	into	into	ADP
dti-2574	58	28	the	the	DET
dti-2574	58	29	tail	tail	NOUN
dti-2574	58	30	vein	vein	NOUN
dti-2574	58	31	at	at	ADP
dti-2574	58	32	the	the	DET
dti-2574	58	33	beginning	beginning	NOUN
dti-2574	58	34	of	of	ADP
dti-2574	58	35	the	the	DET
dti-2574	58	36	experiment	experiment	NOUN
dti-2574	58	37	and	and	CCONJ
dti-2574	58	38	then	then	ADV
dti-2574	58	39	a	a	DET
dti-2574	58	40	maintenance	maintenance	NOUN
dti-2574	58	41	of	of	ADP
dti-2574	58	42	the	the	DET
dti-2574	58	43	treatment	treatment	NOUN
dti-2574	58	44	was	be	AUX
dti-2574	58	45	achieved	achieve	VERB
dti-2574	58	46	by	by	ADP
dti-2574	58	47	an	an	DET
dti-2574	58	48	infusion	infusion	NOUN
dti-2574	58	49	in	in	ADP
dti-2574	58	50	the	the	DET
dti-2574	58	51	left	left	ADJ
dti-2574	58	52	jugular	jugular	ADJ
dti-2574	58	53	vein	vein	NOUN
dti-2574	58	54	of	of	ADP
dti-2574	58	55	levosimendan	levosimendan	PROPN
dti-2574	58	56	(	(	PUNCT
dti-2574	58	57	0.2	0.2	NUM
dti-2574	58	58	µg	µg	ADV
dti-2574	58	59	/	/	SYM
dti-2574	58	60	kg	kg	NOUN
dti-2574	58	61	/	/	SYM
dti-2574	58	62	min	min	NOUN
dti-2574	58	63	)	)	PUNCT
dti-2574	58	64	(	(	PUNCT
dti-2574	58	65	22	22	NUM
dti-2574	58	66	)	)	PUNCT
dti-2574	58	67	.	.	PUNCT
dti-2574	59	1	pulmonary	pulmonary	ADJ
dti-2574	59	2	function	function	NOUN
dti-2574	59	3	for	for	ADP
dti-2574	59	4	the	the	DET
dti-2574	59	5	lung	lung	NOUN
dti-2574	59	6	mechanical	mechanical	ADJ
dti-2574	59	7	properties	property	NOUN
dti-2574	59	8	,	,	PUNCT
dti-2574	59	9	a	a	DET
dti-2574	59	10	pressure	pressure	NOUN
dti-2574	59	11	to	to	PART
dti-2574	59	12	volume	volume	VERB
dti-2574	59	13	(	(	PUNCT
dti-2574	59	14	pv	pv	NOUN
dti-2574	59	15	)	)	PUNCT
dti-2574	59	16	curve	curve	NOUN
dti-2574	59	17	was	be	AUX
dti-2574	59	18	calculated	calculate	VERB
dti-2574	59	19	.	.	PUNCT
dti-2574	60	1	after	after	ADP
dti-2574	60	2	a	a	DET
dti-2574	60	3	recruitment	recruitment	NOUN
dti-2574	60	4	maneuver	maneuver	NOUN
dti-2574	60	5	,	,	PUNCT
dti-2574	60	6	five	five	NUM
dti-2574	60	7	steps	step	NOUN
dti-2574	60	8	of	of	ADP
dti-2574	60	9	0.5	0.5	NUM
dti-2574	60	10	ml	ml	NOUN
dti-2574	60	11	inspiratory	inspiratory	NOUN
dti-2574	60	12	volumes	volume	NOUN
dti-2574	60	13	(	(	PUNCT
dti-2574	60	14	i.e.	i.e.	X
dti-2574	60	15	,	,	PUNCT
dti-2574	60	16	total	total	ADJ
dti-2574	60	17	2.5	2.5	NUM
dti-2574	60	18	ml	ml	NOUN
dti-2574	60	19	)	)	PUNCT
dti-2574	60	20	were	be	AUX
dti-2574	60	21	delivered	deliver	VERB
dti-2574	60	22	into	into	ADP
dti-2574	60	23	the	the	DET
dti-2574	60	24	lungs	lung	NOUN
dti-2574	60	25	.	.	PUNCT
dti-2574	61	1	for	for	ADP
dti-2574	61	2	each	each	DET
dti-2574	61	3	step	step	NOUN
dti-2574	61	4	,	,	PUNCT
dti-2574	61	5	the	the	DET
dti-2574	61	6	plateau	plateau	NOUN
dti-2574	61	7	pressure	pressure	NOUN
dti-2574	61	8	was	be	AUX
dti-2574	61	9	recorded	record	VERB
dti-2574	61	10	to	to	PART
dti-2574	61	11	calculate	calculate	VERB
dti-2574	61	12	the	the	DET
dti-2574	61	13	static	static	ADJ
dti-2574	61	14	compliance	compliance	NOUN
dti-2574	61	15	.	.	PUNCT
dti-2574	62	1	diaphragmatic	diaphragmatic	ADJ
dti-2574	62	2	contractile	contractile	NOUN
dti-2574	62	3	function	function	NOUN
dti-2574	62	4	diaphragmatic	diaphragmatic	ADJ
dti-2574	62	5	contractile	contractile	NOUN
dti-2574	62	6	function	function	NOUN
dti-2574	62	7	was	be	AUX
dti-2574	62	8	measured	measure	VERB
dti-2574	62	9	as	as	ADP
dti-2574	62	10	already	already	ADV
dti-2574	62	11	described	describe	VERB
dti-2574	62	12	(	(	PUNCT
dti-2574	62	13	23	23	NUM
dti-2574	62	14	)	)	PUNCT
dti-2574	62	15	,	,	PUNCT
dti-2574	62	16	briefly	briefly	ADV
dti-2574	62	17	a	a	DET
dti-2574	62	18	diaphragm	diaphragm	NOUN
dti-2574	62	19	strip	strip	NOUN
dti-2574	62	20	was	be	AUX
dti-2574	62	21	mounted	mount	VERB
dti-2574	62	22	into	into	ADP
dti-2574	62	23	a	a	DET
dti-2574	62	24	tissue	tissue	NOUN
dti-2574	62	25	bath	bath	NOUN
dti-2574	62	26	and	and	CCONJ
dti-2574	62	27	,	,	PUNCT
dti-2574	62	28	through	through	ADP
dti-2574	62	29	an	an	DET
dti-2574	62	30	electric	electric	ADJ
dti-2574	62	31	stimulator	stimulator	NOUN
dti-2574	62	32	,	,	PUNCT
dti-2574	62	33	the	the	DET
dti-2574	62	34	peak	peak	ADJ
dti-2574	62	35	tetanic	tetanic	ADJ
dti-2574	62	36	tension	tension	NOUN
dti-2574	62	37	and	and	CCONJ
dti-2574	62	38	the	the	DET
dti-2574	62	39	force	force	NOUN
dti-2574	62	40	-	-	PUNCT
dti-2574	62	41	frequency	frequency	NOUN
dti-2574	62	42	relationship	relationship	NOUN
dti-2574	62	43	were	be	AUX
dti-2574	62	44	evaluated	evaluate	VERB
dti-2574	62	45	.	.	PUNCT
dti-2574	63	1	histological	histological	ADJ
dti-2574	63	2	analysis	analysis	NOUN
dti-2574	63	3	:	:	PUNCT
dti-2574	63	4	muscular	muscular	ADJ
dti-2574	63	5	fibers	fiber	NOUN
dti-2574	63	6	cross	cross	ADJ
dti-2574	63	7	-	-	ADJ
dti-2574	63	8	sectional	sectional	ADJ
dti-2574	63	9	area	area	NOUN
dti-2574	63	10	a	a	DET
dti-2574	63	11	section	section	NOUN
dti-2574	63	12	from	from	ADP
dti-2574	63	13	the	the	DET
dti-2574	63	14	right	right	NOUN
dti-2574	63	15	and	and	CCONJ
dti-2574	63	16	one	one	NUM
dti-2574	63	17	from	from	ADP
dti-2574	63	18	the	the	DET
dti-2574	63	19	left	left	ADJ
dti-2574	63	20	hemidiaphragm	hemidiaphragm	NOUN
dti-2574	63	21	tissue	tissue	NOUN
dti-2574	63	22	was	be	AUX
dti-2574	63	23	used	use	VERB
dti-2574	63	24	for	for	ADP
dti-2574	63	25	histology	histology	NOUN
dti-2574	63	26	analysis	analysis	NOUN
dti-2574	63	27	.	.	PUNCT
dti-2574	64	1	the	the	DET
dti-2574	64	2	cross	cross	PROPN
dti-2574	64	3	sectional	sectional	PROPN
dti-2574	64	4	area	area	NOUN
dti-2574	64	5	(	(	PUNCT
dti-2574	64	6	csa	csa	PROPN
dti-2574	64	7	)	)	PUNCT
dti-2574	64	8	of	of	ADP
dti-2574	64	9	the	the	DET
dti-2574	64	10	muscular	muscular	ADJ
dti-2574	64	11	fiber	fiber	NOUN
dti-2574	64	12	was	be	AUX
dti-2574	64	13	determined	determine	VERB
dti-2574	64	14	by	by	ADP
dti-2574	64	15	manually	manually	ADV
dti-2574	64	16	tracing	trace	VERB
dti-2574	64	17	the	the	DET
dti-2574	64	18	cell	cell	NOUN
dti-2574	64	19	contour	contour	NOUN
dti-2574	64	20	on	on	ADP
dti-2574	64	21	digitized	digitize	VERB
dti-2574	64	22	zambelli	zambelli	PROPN
dti-2574	64	23	et	et	PROPN
dti-2574	64	24	al	al	PROPN
dti-2574	64	25	drug	drug	PROPN
dti-2574	64	26	target	target	NOUN
dti-2574	64	27	insights	insight	NOUN
dti-2574	64	28	2023	2023	NUM
dti-2574	64	29	;	;	PUNCT
dti-2574	64	30	17	17	NUM
dti-2574	64	31	:	:	SYM
dti-2574	64	32	41	41	NUM
dti-2574	64	33	©	©	PROPN
dti-2574	64	34	2023	2023	NUM
dti-2574	64	35	the	the	DET
dti-2574	64	36	authors	author	NOUN
dti-2574	64	37	.	.	PUNCT
dti-2574	65	1	published	publish	VERB
dti-2574	65	2	by	by	ADP
dti-2574	65	3	aboutscience	aboutscience	NOUN
dti-2574	65	4	www.aboutscience.eu	www.aboutscience.eu	NOUN
dti-2574	65	5	images	image	NOUN
dti-2574	65	6	from	from	ADP
dti-2574	65	7	hematoxylin	hematoxylin	NOUN
dti-2574	65	8	and	and	CCONJ
dti-2574	65	9	eosin	eosin	NOUN
dti-2574	65	10	-	-	PUNCT
dti-2574	65	11	stained	stain	VERB
dti-2574	65	12	frozen	frozen	ADJ
dti-2574	65	13	section	section	NOUN
dti-2574	65	14	.	.	PUNCT
dti-2574	66	1	the	the	DET
dti-2574	66	2	csa	csa	PROPN
dti-2574	66	3	of	of	ADP
dti-2574	66	4	at	at	ADV
dti-2574	66	5	least	least	ADV
dti-2574	66	6	150	150	NUM
dti-2574	66	7	fibers	fiber	NOUN
dti-2574	66	8	per	per	ADP
dti-2574	66	9	diaphragm	diaphragm	NOUN
dti-2574	66	10	were	be	AUX
dti-2574	66	11	then	then	ADV
dti-2574	66	12	averaged	average	VERB
dti-2574	66	13	.	.	PUNCT
dti-2574	67	1	western	western	ADJ
dti-2574	67	2	blot	blot	NOUN
dti-2574	67	3	analysis	analysis	NOUN
dti-2574	67	4	another	another	DET
dti-2574	67	5	section	section	NOUN
dti-2574	67	6	of	of	ADP
dti-2574	67	7	the	the	DET
dti-2574	67	8	diaphragm	diaphragm	NOUN
dti-2574	67	9	excised	excise	VERB
dti-2574	67	10	at	at	ADP
dti-2574	67	11	the	the	DET
dti-2574	67	12	sacrifice	sacrifice	NOUN
dti-2574	67	13	was	be	AUX
dti-2574	67	14	immediately	immediately	ADV
dti-2574	67	15	frozen	freeze	VERB
dti-2574	67	16	in	in	ADP
dti-2574	67	17	liquid	liquid	ADJ
dti-2574	67	18	nitrogen	nitrogen	NOUN
dti-2574	67	19	and	and	CCONJ
dti-2574	67	20	stored	store	VERB
dti-2574	67	21	at	at	ADP
dti-2574	67	22	−80	−80	PROPN
dti-2574	67	23	°	°	ADP
dti-2574	67	24	c	c	NOUN
dti-2574	67	25	.	.	PUNCT
dti-2574	68	1	the	the	DET
dti-2574	68	2	cytoplasmic	cytoplasmic	ADJ
dti-2574	68	3	extraction	extraction	NOUN
dti-2574	68	4	was	be	AUX
dti-2574	68	5	prepared	prepare	VERB
dti-2574	68	6	using	use	VERB
dti-2574	68	7	an	an	DET
dti-2574	68	8	ne	ne	NOUN
dti-2574	68	9	-	-	NOUN
dti-2574	68	10	per	per	ADP
dti-2574	68	11	nuclear	nuclear	ADJ
dti-2574	68	12	cytoplasmic	cytoplasmic	ADJ
dti-2574	68	13	extraction	extraction	NOUN
dti-2574	68	14	reagent	reagent	NOUN
dti-2574	68	15	kit	kit	NOUN
dti-2574	68	16	(	(	PUNCT
dti-2574	68	17	pierce	pierce	PROPN
dti-2574	68	18	,	,	PUNCT
dti-2574	68	19	rockford	rockford	PROPN
dti-2574	68	20	,	,	PUNCT
dti-2574	68	21	il	il	PROPN
dti-2574	68	22	,	,	PUNCT
dti-2574	68	23	usa	usa	PROPN
dti-2574	68	24	)	)	PUNCT
dti-2574	68	25	according	accord	VERB
dti-2574	68	26	to	to	ADP
dti-2574	68	27	the	the	DET
dti-2574	68	28	manufacturer	manufacturer	NOUN
dti-2574	68	29	’s	’s	PART
dti-2574	68	30	instruction	instruction	NOUN
dti-2574	68	31	.	.	PUNCT
dti-2574	69	1	equal	equal	ADJ
dti-2574	69	2	amounts	amount	NOUN
dti-2574	69	3	of	of	ADP
dti-2574	69	4	the	the	DET
dti-2574	69	5	protein	protein	NOUN
dti-2574	69	6	concentrations	concentration	NOUN
dti-2574	69	7	were	be	AUX
dti-2574	69	8	quantified	quantify	VERB
dti-2574	69	9	by	by	ADP
dti-2574	69	10	the	the	DET
dti-2574	69	11	bicinchoninic	bicinchoninic	ADJ
dti-2574	69	12	acid	acid	NOUN
dti-2574	69	13	assay	assay	NOUN
dti-2574	69	14	(	(	PUNCT
dti-2574	69	15	bca	bca	PROPN
dti-2574	69	16	assay	assay	PROPN
dti-2574	69	17	;	;	PUNCT
dti-2574	69	18	pierce	pierce	PROPN
dti-2574	69	19	,	,	PUNCT
dti-2574	69	20	rockford	rockford	PROPN
dti-2574	69	21	,	,	PUNCT
dti-2574	69	22	il	il	PROPN
dti-2574	69	23	,	,	PUNCT
dti-2574	69	24	usa	usa	PROPN
dti-2574	69	25	)	)	PUNCT
dti-2574	69	26	,	,	PUNCT
dti-2574	69	27	and	and	CCONJ
dti-2574	69	28	each	each	DET
dti-2574	69	29	sample	sample	NOUN
dti-2574	69	30	was	be	AUX
dti-2574	69	31	analyzed	analyze	VERB
dti-2574	69	32	according	accord	VERB
dti-2574	69	33	to	to	ADP
dti-2574	69	34	standard	standard	ADJ
dti-2574	69	35	western	western	ADJ
dti-2574	69	36	blotting	blotting	ADJ
dti-2574	69	37	protocols	protocol	NOUN
dti-2574	69	38	.	.	PUNCT
dti-2574	70	1	the	the	DET
dti-2574	70	2	following	follow	VERB
dti-2574	70	3	antibodies	antibody	NOUN
dti-2574	70	4	were	be	AUX
dti-2574	70	5	used	use	VERB
dti-2574	70	6	:	:	PUNCT
dti-2574	70	7	atrogin	atrogin	NOUN
dti-2574	70	8	(	(	PUNCT
dti-2574	70	9	ap2041	ap2041	PROPN
dti-2574	70	10	;	;	PUNCT
dti-2574	70	11	ecm	ecm	PROPN
dti-2574	70	12	biosciences	bioscience	NOUN
dti-2574	70	13	,	,	PUNCT
dti-2574	70	14	versailles	versaille	NOUN
dti-2574	70	15	,	,	PUNCT
dti-2574	70	16	ky	ky	PROPN
dti-2574	70	17	,	,	PUNCT
dti-2574	70	18	usa	usa	PROPN
dti-2574	70	19	)	)	PUNCT
dti-2574	70	20	and	and	CCONJ
dti-2574	70	21	lc3b	lc3b	PROPN
dti-2574	70	22	(	(	PUNCT
dti-2574	70	23	light	light	ADJ
dti-2574	70	24	chain	chain	NOUN
dti-2574	70	25	3	3	NUM
dti-2574	70	26	,	,	PUNCT
dti-2574	70	27	isoform	isoform	NOUN
dti-2574	70	28	b	b	PROPN
dti-2574	70	29	ii	ii	PROPN
dti-2574	70	30	,	,	PUNCT
dti-2574	70	31	2775	2775	NUM
dti-2574	70	32	;	;	PUNCT
dti-2574	70	33	cell	cell	NOUN
dti-2574	70	34	signaling	signal	VERB
dti-2574	70	35	technology	technology	NOUN
dti-2574	70	36	,	,	PUNCT
dti-2574	70	37	danvers	danver	NOUN
dti-2574	70	38	,	,	PUNCT
dti-2574	70	39	ma	ma	PROPN
dti-2574	70	40	,	,	PUNCT
dti-2574	70	41	usa	usa	PROPN
dti-2574	70	42	)	)	PUNCT
dti-2574	70	43	.	.	PUNCT
dti-2574	71	1	the	the	DET
dti-2574	71	2	antibody	antibody	NOUN
dti-2574	71	3	α	α	NOUN
dti-2574	71	4	-	-	PUNCT
dti-2574	71	5	tubulin	tubulin	NOUN
dti-2574	71	6	(	(	PUNCT
dti-2574	71	7	#	#	SYM
dti-2574	71	8	2125	2125	NUM
dti-2574	71	9	;	;	PUNCT
dti-2574	71	10	cell	cell	NOUN
dti-2574	71	11	signaling	signaling	NOUN
dti-2574	71	12	,	,	PUNCT
dti-2574	71	13	danvers	danver	NOUN
dti-2574	71	14	,	,	PUNCT
dti-2574	71	15	ma	ma	PROPN
dti-2574	71	16	,	,	PUNCT
dti-2574	71	17	usa	usa	PROPN
dti-2574	71	18	)	)	PUNCT
dti-2574	71	19	was	be	AUX
dti-2574	71	20	used	use	VERB
dti-2574	71	21	as	as	ADP
dti-2574	71	22	the	the	DET
dti-2574	71	23	reference	reference	NOUN
dti-2574	71	24	of	of	ADP
dti-2574	71	25	internal	internal	ADJ
dti-2574	71	26	control	control	NOUN
dti-2574	71	27	.	.	PUNCT
dti-2574	72	1	statistical	statistical	ADJ
dti-2574	72	2	analysis	analysis	NOUN
dti-2574	72	3	data	datum	NOUN
dti-2574	72	4	are	be	AUX
dti-2574	72	5	expressed	express	VERB
dti-2574	72	6	as	as	ADP
dti-2574	72	7	mean	mean	NOUN
dti-2574	72	8	±	±	NUM
dti-2574	72	9	standard	standard	ADJ
dti-2574	72	10	error	error	NOUN
dti-2574	72	11	of	of	ADP
dti-2574	72	12	the	the	DET
dti-2574	72	13	mean	mean	NOUN
dti-2574	72	14	(	(	PUNCT
dti-2574	72	15	sem	sem	NOUN
dti-2574	72	16	)	)	PUNCT
dti-2574	72	17	.	.	PUNCT
dti-2574	73	1	differences	difference	NOUN
dti-2574	73	2	in	in	ADP
dti-2574	73	3	variances	variance	NOUN
dti-2574	73	4	between	between	ADP
dti-2574	73	5	groups	group	NOUN
dti-2574	73	6	were	be	AUX
dti-2574	73	7	assessed	assess	VERB
dti-2574	73	8	by	by	ADP
dti-2574	73	9	one	one	NUM
dti-2574	73	10	-	-	PUNCT
dti-2574	73	11	way	way	NOUN
dti-2574	73	12	analysis	analysis	NOUN
dti-2574	73	13	of	of	ADP
dti-2574	73	14	variance	variance	NOUN
dti-2574	73	15	(	(	PUNCT
dti-2574	73	16	anova	anova	PROPN
dti-2574	73	17	)	)	PUNCT
dti-2574	73	18	.	.	PUNCT
dti-2574	74	1	post	post	VERB
dti-2574	74	2	hoc	hoc	X
dti-2574	74	3	comparisons	comparison	NOUN
dti-2574	74	4	were	be	AUX
dti-2574	74	5	performed	perform	VERB
dti-2574	74	6	by	by	ADP
dti-2574	74	7	benjamini	benjamini	NOUN
dti-2574	74	8	,	,	PUNCT
dti-2574	74	9	krieger	krieger	NOUN
dti-2574	74	10	and	and	CCONJ
dti-2574	74	11	yekutieli	yekutieli	PROPN
dti-2574	74	12	.	.	PUNCT
dti-2574	75	1	differences	difference	NOUN
dti-2574	75	2	in	in	ADP
dti-2574	75	3	physiological	physiological	ADJ
dti-2574	75	4	variables	variable	NOUN
dti-2574	75	5	between	between	ADP
dti-2574	75	6	vidd	vidd	NOUN
dti-2574	75	7	and	and	CCONJ
dti-2574	75	8	vidd+levo	vidd+levo	PROPN
dti-2574	75	9	were	be	AUX
dti-2574	75	10	performed	perform	VERB
dti-2574	75	11	by	by	ADP
dti-2574	75	12	unpaired	unpaired	ADJ
dti-2574	75	13	t	t	NOUN
dti-2574	75	14	-	-	PUNCT
dti-2574	75	15	test	test	NOUN
dti-2574	75	16	.	.	PUNCT
dti-2574	76	1	p	p	X
dti-2574	76	2	-	-	PUNCT
dti-2574	76	3	values	value	NOUN
dti-2574	76	4	<	<	X
dti-2574	76	5	0.05	0.05	NUM
dti-2574	76	6	were	be	AUX
dti-2574	76	7	considered	consider	VERB
dti-2574	76	8	as	as	ADP
dti-2574	76	9	statistically	statistically	ADV
dti-2574	76	10	significant	significant	ADJ
dti-2574	76	11	(	(	PUNCT
dti-2574	76	12	two	two	NUM
dti-2574	76	13	-	-	PUNCT
dti-2574	76	14	tailed	tail	VERB
dti-2574	76	15	)	)	PUNCT
dti-2574	76	16	.	.	PUNCT
dti-2574	77	1	statistical	statistical	ADJ
dti-2574	77	2	analysis	analysis	NOUN
dti-2574	77	3	was	be	AUX
dti-2574	77	4	performed	perform	VERB
dti-2574	77	5	by	by	ADP
dti-2574	77	6	graphpad	graphpad	NOUN
dti-2574	77	7	prism	prism	NOUN
dti-2574	77	8	(	(	PUNCT
dti-2574	77	9	version	version	NOUN
dti-2574	77	10	8.4.2	8.4.2	NUM
dti-2574	77	11	)	)	PUNCT
dti-2574	77	12	.	.	PUNCT
dti-2574	78	1	some	some	DET
dti-2574	78	2	histologic	histologic	ADJ
dti-2574	78	3	and	and	CCONJ
dti-2574	78	4	western	western	ADJ
dti-2574	78	5	blot	blot	NOUN
dti-2574	78	6	analyses	analysis	NOUN
dti-2574	78	7	could	could	AUX
dti-2574	78	8	not	not	PART
dti-2574	78	9	be	be	AUX
dti-2574	78	10	performed	perform	VERB
dti-2574	78	11	in	in	ADP
dti-2574	78	12	some	some	DET
dti-2574	78	13	animals	animal	NOUN
dti-2574	78	14	because	because	SCONJ
dti-2574	78	15	of	of	ADP
dti-2574	78	16	technical	technical	ADJ
dti-2574	78	17	problems	problem	NOUN
dti-2574	78	18	.	.	PUNCT
dti-2574	79	1	results	result	VERB
dti-2574	79	2	systemic	systemic	ADJ
dti-2574	79	3	response	response	NOUN
dti-2574	79	4	no	no	DET
dti-2574	79	5	rats	rat	NOUN
dti-2574	79	6	died	die	VERB
dti-2574	79	7	during	during	ADP
dti-2574	79	8	the	the	DET
dti-2574	79	9	experiments	experiment	NOUN
dti-2574	79	10	.	.	PUNCT
dti-2574	80	1	in	in	ADP
dti-2574	80	2	terms	term	NOUN
dti-2574	80	3	of	of	ADP
dti-2574	80	4	body	body	NOUN
dti-2574	80	5	weight	weight	NOUN
dti-2574	80	6	,	,	PUNCT
dti-2574	80	7	no	no	DET
dti-2574	80	8	differences	difference	NOUN
dti-2574	80	9	were	be	AUX
dti-2574	80	10	found	find	VERB
dti-2574	80	11	between	between	ADP
dti-2574	80	12	groups	group	NOUN
dti-2574	80	13	(	(	PUNCT
dti-2574	80	14	healthy	healthy	ADJ
dti-2574	80	15	:	:	PUNCT
dti-2574	80	16	310	310	NUM
dti-2574	80	17	±	±	NUM
dti-2574	80	18	6	6	NUM
dti-2574	80	19	,	,	PUNCT
dti-2574	80	20	vidd	vidd	NOUN
dti-2574	80	21	:	:	PUNCT
dti-2574	80	22	300	300	NUM
dti-2574	80	23	±	±	NUM
dti-2574	80	24	6	6	NUM
dti-2574	80	25	,	,	PUNCT
dti-2574	80	26	vidd	vidd	NOUN
dti-2574	80	27	+	+	CCONJ
dti-2574	80	28	levo	levo	PROPN
dti-2574	80	29	:	:	PUNCT
dti-2574	80	30	295	295	NUM
dti-2574	80	31	±	±	NUM
dti-2574	80	32	7	7	NUM
dti-2574	80	33	g	g	NOUN
dti-2574	80	34	;	;	PUNCT
dti-2574	80	35	anova	anova	PROPN
dti-2574	80	36	p	p	X
dti-2574	80	37	=	=	PROPN
dti-2574	80	38	0.25	0.25	NUM
dti-2574	80	39	)	)	PUNCT
dti-2574	80	40	.	.	PUNCT
dti-2574	81	1	the	the	DET
dti-2574	81	2	mean	mean	ADJ
dti-2574	81	3	arterial	arterial	ADJ
dti-2574	81	4	pressure	pressure	NOUN
dti-2574	81	5	(	(	PUNCT
dti-2574	81	6	map	map	NOUN
dti-2574	81	7	)	)	PUNCT
dti-2574	81	8	was	be	AUX
dti-2574	81	9	similar	similar	ADJ
dti-2574	81	10	between	between	ADP
dti-2574	81	11	the	the	DET
dti-2574	81	12	test	test	NOUN
dti-2574	81	13	groups	group	NOUN
dti-2574	81	14	at	at	ADP
dti-2574	81	15	the	the	DET
dti-2574	81	16	beginning	beginning	NOUN
dti-2574	81	17	of	of	ADP
dti-2574	81	18	the	the	DET
dti-2574	81	19	experiment	experiment	NOUN
dti-2574	81	20	and	and	CCONJ
dti-2574	81	21	after	after	ADP
dti-2574	81	22	3	3	NUM
dti-2574	81	23	hours	hour	NOUN
dti-2574	81	24	of	of	ADP
dti-2574	81	25	mv	mv	PROPN
dti-2574	81	26	.	.	PUNCT
dti-2574	82	1	at	at	ADP
dti-2574	82	2	the	the	DET
dti-2574	82	3	end	end	NOUN
dti-2574	82	4	of	of	ADP
dti-2574	82	5	the	the	DET
dti-2574	82	6	mv	mv	PROPN
dti-2574	82	7	,	,	PUNCT
dti-2574	82	8	rats	rat	NOUN
dti-2574	82	9	without	without	ADP
dti-2574	82	10	levosimendan	levosimendan	PROPN
dti-2574	82	11	treatment	treatment	NOUN
dti-2574	82	12	showed	show	VERB
dti-2574	82	13	a	a	DET
dti-2574	82	14	significant	significant	ADJ
dti-2574	82	15	lower	low	ADJ
dti-2574	82	16	map	map	NOUN
dti-2574	82	17	versus	versus	ADP
dti-2574	82	18	vidd	vidd	NOUN
dti-2574	82	19	+	+	CCONJ
dti-2574	82	20	levo	levo	PROPN
dti-2574	82	21	group	group	NOUN
dti-2574	82	22	,	,	PUNCT
dti-2574	82	23	as	as	SCONJ
dti-2574	82	24	demonstrated	demonstrate	VERB
dti-2574	82	25	in	in	ADP
dti-2574	82	26	table	table	NOUN
dti-2574	82	27	i.	i.	NOUN
dti-2574	82	28	the	the	DET
dti-2574	82	29	difference	difference	NOUN
dti-2574	82	30	in	in	ADP
dti-2574	82	31	map	map	NOUN
dti-2574	82	32	was	be	AUX
dti-2574	82	33	not	not	PART
dti-2574	82	34	influenced	influence	VERB
dti-2574	82	35	by	by	ADP
dti-2574	82	36	a	a	DET
dti-2574	82	37	difference	difference	NOUN
dti-2574	82	38	in	in	ADP
dti-2574	82	39	terms	term	NOUN
dti-2574	82	40	of	of	ADP
dti-2574	82	41	fluid	fluid	ADJ
dti-2574	82	42	balance	balance	NOUN
dti-2574	82	43	,	,	PUNCT
dti-2574	82	44	since	since	SCONJ
dti-2574	82	45	it	it	PRON
dti-2574	82	46	was	be	AUX
dti-2574	82	47	similar	similar	ADJ
dti-2574	82	48	between	between	ADP
dti-2574	82	49	two	two	NUM
dti-2574	82	50	groups	group	NOUN
dti-2574	82	51	(	(	PUNCT
dti-2574	82	52	vidd	vidd	NOUN
dti-2574	82	53	:	:	PUNCT
dti-2574	82	54	18.6	18.6	NUM
dti-2574	82	55	±	±	NUM
dti-2574	82	56	0.6	0.6	NUM
dti-2574	82	57	ml	ml	NOUN
dti-2574	82	58	vs.	vs.	ADP
dti-2574	82	59	vidd	vidd	NOUN
dti-2574	82	60	+	+	CCONJ
dti-2574	82	61	levo	levo	PROPN
dti-2574	82	62	:	:	PUNCT
dti-2574	82	63	19.9	19.9	NUM
dti-2574	82	64	±	±	NUM
dti-2574	82	65	1.3	1.3	NUM
dti-2574	82	66	ml	ml	NOUN
dti-2574	82	67	,	,	PUNCT
dti-2574	82	68	p	p	X
dti-2574	82	69	=	=	NOUN
dti-2574	82	70	0.31	0.31	NUM
dti-2574	82	71	)	)	PUNCT
dti-2574	82	72	.	.	PUNCT
dti-2574	83	1	regarding	regard	VERB
dti-2574	83	2	the	the	DET
dti-2574	83	3	respiratory	respiratory	ADJ
dti-2574	83	4	function	function	NOUN
dti-2574	83	5	,	,	PUNCT
dti-2574	83	6	no	no	DET
dti-2574	83	7	differences	difference	NOUN
dti-2574	83	8	were	be	AUX
dti-2574	83	9	found	find	VERB
dti-2574	83	10	between	between	ADP
dti-2574	83	11	ventilated	ventilate	VERB
dti-2574	83	12	groups	group	NOUN
dti-2574	83	13	in	in	ADP
dti-2574	83	14	oxygenation	oxygenation	NOUN
dti-2574	83	15	nor	nor	CCONJ
dti-2574	83	16	in	in	ADP
dti-2574	83	17	respiratory	respiratory	ADJ
dti-2574	83	18	system	system	NOUN
dti-2574	83	19	static	static	ADJ
dti-2574	83	20	compliance	compliance	NOUN
dti-2574	83	21	.	.	PUNCT
dti-2574	84	1	histological	histological	ADJ
dti-2574	84	2	analysis	analysis	NOUN
dti-2574	84	3	levosimendan	levosimendan	PROPN
dti-2574	84	4	treatment	treatment	NOUN
dti-2574	84	5	seemed	seem	VERB
dti-2574	84	6	to	to	PART
dti-2574	84	7	induce	induce	VERB
dti-2574	84	8	a	a	DET
dti-2574	84	9	protection	protection	NOUN
dti-2574	84	10	in	in	ADP
dti-2574	84	11	muscle	muscle	NOUN
dti-2574	84	12	fiber	fiber	NOUN
dti-2574	84	13	size	size	NOUN
dti-2574	84	14	from	from	ADP
dti-2574	84	15	cellular	cellular	ADJ
dti-2574	84	16	atrophy	atrophy	NOUN
dti-2574	84	17	induced	induce	VERB
dti-2574	84	18	by	by	ADP
dti-2574	84	19	mv	mv	PROPN
dti-2574	84	20	.	.	PROPN
dti-2574	85	1	as	as	SCONJ
dti-2574	85	2	shown	show	VERB
dti-2574	85	3	in	in	ADP
dti-2574	85	4	figure	figure	NOUN
dti-2574	85	5	1	1	NUM
dti-2574	85	6	,	,	PUNCT
dti-2574	85	7	mv	mv	PROPN
dti-2574	85	8	affects	affect	VERB
dti-2574	85	9	the	the	DET
dti-2574	85	10	cross	cross	ADJ
dti-2574	85	11	-	-	ADJ
dti-2574	85	12	sectional	sectional	ADJ
dti-2574	85	13	fiber	fiber	NOUN
dti-2574	85	14	area	area	NOUN
dti-2574	85	15	in	in	ADP
dti-2574	85	16	table	table	NOUN
dti-2574	85	17	i	i	PRON
dti-2574	85	18	mean	mean	VERB
dti-2574	85	19	arterial	arterial	ADJ
dti-2574	85	20	pressure	pressure	NOUN
dti-2574	85	21	,	,	PUNCT
dti-2574	85	22	heart	heart	NOUN
dti-2574	85	23	rate	rate	NOUN
dti-2574	85	24	,	,	PUNCT
dti-2574	85	25	pao2	pao2	PROPN
dti-2574	85	26	/	/	SYM
dti-2574	85	27	fio2	fio2	PROPN
dti-2574	85	28	,	,	PUNCT
dti-2574	85	29	respiratory	respiratory	ADJ
dti-2574	85	30	system	system	NOUN
dti-2574	85	31	static	static	ADJ
dti-2574	85	32	compliance	compliance	NOUN
dti-2574	85	33	vidd	vidd	NOUN
dti-2574	85	34	vidd	vidd	NOUN
dti-2574	85	35	+	+	CCONJ
dti-2574	85	36	levo	levo	PROPN
dti-2574	85	37	p	p	NOUN
dti-2574	85	38	values	value	NOUN
dti-2574	85	39	mean	mean	VERB
dti-2574	85	40	arterial	arterial	ADJ
dti-2574	85	41	pressure	pressure	NOUN
dti-2574	85	42	(	(	PUNCT
dti-2574	85	43	mm	mm	PROPN
dti-2574	85	44	hg	hg	NOUN
dti-2574	85	45	)	)	PUNCT
dti-2574	85	46	start	start	VERB
dti-2574	85	47	90	90	NUM
dti-2574	85	48	±	±	NUM
dti-2574	85	49	5	5	NUM
dti-2574	85	50	91	91	NUM
dti-2574	85	51	±	±	NUM
dti-2574	85	52	11	11	NUM
dti-2574	85	53	0.93	0.93	NUM
dti-2574	85	54	3	3	NUM
dti-2574	85	55	hours	hour	NOUN
dti-2574	85	56	94	94	NUM
dti-2574	85	57	±	±	NUM
dti-2574	85	58	6	6	NUM
dti-2574	85	59	97	97	NUM
dti-2574	85	60	±	±	NUM
dti-2574	85	61	9	9	NUM
dti-2574	85	62	0.78	0.78	NUM
dti-2574	85	63	end	end	NOUN
dti-2574	85	64	66	66	NUM
dti-2574	85	65	±	±	NUM
dti-2574	85	66	6	6	NUM
dti-2574	85	67	89	89	NUM
dti-2574	85	68	±	±	NUM
dti-2574	85	69	10	10	NUM
dti-2574	85	70	0.04	0.04	NUM
dti-2574	85	71	*	*	PUNCT
dti-2574	85	72	heart	heart	NOUN
dti-2574	85	73	rate	rate	NOUN
dti-2574	85	74	(	(	PUNCT
dti-2574	85	75	/min	/min	PUNCT
dti-2574	85	76	)	)	PUNCT
dti-2574	85	77	start	start	VERB
dti-2574	85	78	254	254	NUM
dti-2574	85	79	±	±	NUM
dti-2574	85	80	10	10	NUM
dti-2574	85	81	285	285	NUM
dti-2574	85	82	±	±	NUM
dti-2574	85	83	16	16	NUM
dti-2574	85	84	0.10	0.10	NUM
dti-2574	85	85	3	3	NUM
dti-2574	85	86	hours	hour	NOUN
dti-2574	85	87	329	329	NUM
dti-2574	85	88	±	±	NUM
dti-2574	85	89	12	12	NUM
dti-2574	85	90	329	329	NUM
dti-2574	85	91	±	±	NUM
dti-2574	85	92	6	6	NUM
dti-2574	85	93	0.95	0.95	NUM
dti-2574	85	94	end	end	NOUN
dti-2574	85	95	306	306	NUM
dti-2574	85	96	±	±	NUM
dti-2574	85	97	12	12	NUM
dti-2574	85	98	330	330	NUM
dti-2574	85	99	±	±	NUM
dti-2574	85	100	9	9	NUM
dti-2574	85	101	0.15	0.15	NUM
dti-2574	85	102	pao2	pao2	PROPN
dti-2574	85	103	/	/	SYM
dti-2574	85	104	fio2	fio2	PROPN
dti-2574	85	105	end	end	VERB
dti-2574	85	106	476	476	NUM
dti-2574	85	107	±	±	NUM
dti-2574	85	108	48	48	NUM
dti-2574	85	109	529	529	NUM
dti-2574	85	110	±	±	NUM
dti-2574	85	111	13	13	NUM
dti-2574	85	112	0.25	0.25	NUM
dti-2574	85	113	respiratory	respiratory	ADJ
dti-2574	85	114	system	system	NOUN
dti-2574	85	115	static	static	ADJ
dti-2574	85	116	compliance	compliance	NOUN
dti-2574	85	117	(	(	PUNCT
dti-2574	85	118	ml	ml	NOUN
dti-2574	85	119	/	/	SYM
dti-2574	85	120	cmh2o	cmh2o	NOUN
dti-2574	85	121	)	)	PUNCT
dti-2574	85	122	end	end	VERB
dti-2574	85	123	0.34	0.34	NUM
dti-2574	85	124	±	±	NUM
dti-2574	85	125	0.01	0.01	NUM
dti-2574	85	126	0.32	0.32	NUM
dti-2574	85	127	±	±	NUM
dti-2574	85	128	0.01	0.01	NUM
dti-2574	85	129	0.38	0.38	NUM
dti-2574	85	130	all	all	DET
dti-2574	85	131	parameters	parameter	NOUN
dti-2574	85	132	were	be	AUX
dti-2574	85	133	measured	measure	VERB
dti-2574	85	134	during	during	ADP
dti-2574	85	135	mechanical	mechanical	ADJ
dti-2574	85	136	ventilation	ventilation	NOUN
dti-2574	85	137	.	.	PUNCT
dti-2574	86	1	vidd	vidd	NOUN
dti-2574	86	2	:	:	PUNCT
dti-2574	87	1	mv	mv	PROPN
dti-2574	87	2	+	+	CCONJ
dti-2574	87	3	no	no	DET
dti-2574	87	4	treatment	treatment	NOUN
dti-2574	87	5	(	(	PUNCT
dti-2574	87	6	n	n	NOUN
dti-2574	87	7	=	=	NUM
dti-2574	87	8	12	12	NUM
dti-2574	87	9	)	)	PUNCT
dti-2574	87	10	;	;	PUNCT
dti-2574	88	1	vidd+levo	vidd+levo	PROPN
dti-2574	88	2	:	:	PUNCT
dti-2574	88	3	mv	mv	PROPN
dti-2574	88	4	+	+	CCONJ
dti-2574	88	5	levosimendan	levosimendan	PROPN
dti-2574	88	6	treatment	treatment	NOUN
dti-2574	88	7	(	(	PUNCT
dti-2574	88	8	n	n	NOUN
dti-2574	88	9	=	=	SYM
dti-2574	88	10	8)	8)	NUM
dti-2574	88	11	.	.	PUNCT
dti-2574	89	1	mv	mv	PROPN
dti-2574	89	2	=	=	NOUN
dti-2574	89	3	mechanical	mechanical	ADJ
dti-2574	89	4	ventilation	ventilation	NOUN
dti-2574	89	5	;	;	PUNCT
dti-2574	89	6	vidd	vidd	NOUN
dti-2574	89	7	=	=	SYM
dti-2574	89	8	ventilator	ventilator	NOUN
dti-2574	89	9	-	-	PUNCT
dti-2574	89	10	induced	induce	VERB
dti-2574	89	11	diaphragmatic	diaphragmatic	ADJ
dti-2574	89	12	dysfunction	dysfunction	NOUN
dti-2574	89	13	.	.	PUNCT
dti-2574	90	1	*	*	PUNCT
dti-2574	90	2	p	p	X
dti-2574	90	3	<	<	X
dti-2574	90	4	0.05	0.05	NUM
dti-2574	90	5	.	.	PUNCT
dti-2574	90	6	fig	fig	NOUN
dti-2574	90	7	.	.	PUNCT
dti-2574	91	1	1	1	NUM
dti-2574	91	2	diaphragm	diaphragm	NOUN
dti-2574	91	3	fiber	fiber	NOUN
dti-2574	91	4	size	size	NOUN
dti-2574	91	5	.	.	PUNCT
dti-2574	92	1	cross	cross	ADJ
dti-2574	92	2	-	-	ADJ
dti-2574	92	3	sectional	sectional	ADJ
dti-2574	92	4	diaphragmatic	diaphragmatic	ADJ
dti-2574	92	5	fiber	fiber	NOUN
dti-2574	92	6	size	size	NOUN
dti-2574	92	7	in	in	ADP
dti-2574	92	8	histological	histological	ADJ
dti-2574	92	9	slice	slice	NOUN
dti-2574	92	10	.	.	PUNCT
dti-2574	93	1	a	a	DET
dti-2574	93	2	)	)	PUNCT
dti-2574	93	3	histological	histological	ADJ
dti-2574	93	4	images	image	NOUN
dti-2574	93	5	,	,	PUNCT
dti-2574	93	6	hematoxylin	hematoxylin	NOUN
dti-2574	93	7	-	-	PUNCT
dti-2574	93	8	eosin	eosin	NOUN
dti-2574	93	9	staining	staining	NOUN
dti-2574	93	10	,	,	PUNCT
dti-2574	93	11	200×	200×	NOUN
dti-2574	93	12	,	,	PUNCT
dti-2574	93	13	scale	scale	NOUN
dti-2574	93	14	bar	bar	NOUN
dti-2574	93	15	=	=	PUNCT
dti-2574	93	16	200	200	NUM
dti-2574	93	17	µm	µm	NOUN
dti-2574	93	18	.	.	PUNCT
dti-2574	94	1	b	b	X
dti-2574	94	2	)	)	PUNCT
dti-2574	94	3	anova	anova	PROPN
dti-2574	95	1	p	p	X
dti-2574	95	2	<	<	X
dti-2574	95	3	0.01	0.01	NUM
dti-2574	95	4	.	.	PUNCT
dti-2574	96	1	benjamini	benjamini	PROPN
dti-2574	96	2	,	,	PUNCT
dti-2574	96	3	krieger	krieger	PROPN
dti-2574	96	4	and	and	CCONJ
dti-2574	96	5	yekutieli	yekutieli	ADV
dti-2574	96	6	post	post	VERB
dti-2574	96	7	hoc	hoc	X
dti-2574	96	8	test	test	NOUN
dti-2574	96	9	:	:	PUNCT
dti-2574	97	1	p	p	X
dti-2574	97	2	=	=	NOUN
dti-2574	97	3	0.004	0.004	NUM
dti-2574	97	4	vs.	vs.	CCONJ
dti-2574	97	5	healthy	healthy	ADJ
dti-2574	97	6	and	and	CCONJ
dti-2574	97	7	p	p	X
dti-2574	97	8	=	=	NOUN
dti-2574	97	9	0.01	0.01	NUM
dti-2574	97	10	vs.	vs.	ADP
dti-2574	97	11	vidd+levo	vidd+levo	PROPN
dti-2574	97	12	.	.	PUNCT
dti-2574	98	1	healthy	healthy	ADJ
dti-2574	98	2	:	:	PUNCT
dti-2574	99	1	no	no	DET
dti-2574	99	2	surgical	surgical	ADJ
dti-2574	99	3	interventions	intervention	NOUN
dti-2574	99	4	,	,	PUNCT
dti-2574	99	5	no	no	DET
dti-2574	99	6	mv	mv	NOUN
dti-2574	99	7	,	,	PUNCT
dti-2574	99	8	and	and	CCONJ
dti-2574	99	9	no	no	DET
dti-2574	99	10	treatment	treatment	NOUN
dti-2574	99	11	(	(	PUNCT
dti-2574	99	12	n	n	NOUN
dti-2574	99	13	=	=	SYM
dti-2574	99	14	8)	8)	NUM
dti-2574	99	15	;	;	PUNCT
dti-2574	99	16	vidd	vidd	NOUN
dti-2574	99	17	:	:	PUNCT
dti-2574	99	18	surgical	surgical	ADJ
dti-2574	99	19	intervention	intervention	NOUN
dti-2574	99	20	+	+	CCONJ
dti-2574	99	21	mv	mv	PROPN
dti-2574	99	22	and	and	CCONJ
dti-2574	99	23	no	no	DET
dti-2574	99	24	treatment	treatment	NOUN
dti-2574	99	25	(	(	PUNCT
dti-2574	99	26	n	n	NOUN
dti-2574	99	27	=	=	SYM
dti-2574	99	28	10	10	NUM
dti-2574	99	29	)	)	PUNCT
dti-2574	99	30	;	;	PUNCT
dti-2574	99	31	vidd+levo	vidd+levo	NOUN
dti-2574	99	32	:	:	PUNCT
dti-2574	99	33	surgical	surgical	ADJ
dti-2574	99	34	intervention	intervention	NOUN
dti-2574	99	35	+	+	CCONJ
dti-2574	99	36	mv	mv	PROPN
dti-2574	99	37	+	+	CCONJ
dti-2574	99	38	levosimendan	levosimendan	PROPN
dti-2574	99	39	treatment	treatment	NOUN
dti-2574	99	40	(	(	PUNCT
dti-2574	99	41	n	n	NOUN
dti-2574	99	42	=	=	SYM
dti-2574	99	43	8)	8)	NUM
dti-2574	99	44	.	.	PUNCT
dti-2574	99	45	anova	anova	PROPN
dti-2574	100	1	=	=	PUNCT
dti-2574	100	2	analysis	analysis	NOUN
dti-2574	100	3	of	of	ADP
dti-2574	100	4	variance	variance	NOUN
dti-2574	100	5	;	;	PUNCT
dti-2574	100	6	mv	mv	PROPN
dti-2574	100	7	=	=	NOUN
dti-2574	100	8	mechanical	mechanical	ADJ
dti-2574	100	9	ventilation	ventilation	NOUN
dti-2574	100	10	;	;	PUNCT
dti-2574	100	11	vidd	vidd	NOUN
dti-2574	100	12	=	=	SYM
dti-2574	100	13	ventilator	ventilator	NOUN
dti-2574	100	14	-	-	PUNCT
dti-2574	100	15	induced	induce	VERB
dti-2574	100	16	diaphragmatic	diaphragmatic	ADJ
dti-2574	100	17	dysfunction	dysfunction	NOUN
dti-2574	100	18	.	.	PUNCT
dti-2574	101	1	effects	effect	NOUN
dti-2574	101	2	of	of	ADP
dti-2574	101	3	levosimendan	levosimendan	ADJ
dti-2574	101	4	treatment	treatment	NOUN
dti-2574	101	5	on	on	ADP
dti-2574	101	6	diaphragmatic	diaphragmatic	ADJ
dti-2574	101	7	injury42	injury42	NOUN
dti-2574	102	1	©	©	SCONJ
dti-2574	102	2	2023	2023	NUM
dti-2574	102	3	the	the	DET
dti-2574	102	4	authors	author	NOUN
dti-2574	102	5	.	.	PUNCT
dti-2574	102	6	drug	drug	NOUN
dti-2574	102	7	target	target	NOUN
dti-2574	102	8	insights	insight	NOUN
dti-2574	102	9	issn	issn	VERB
dti-2574	102	10	1177	1177	NUM
dti-2574	102	11	-	-	SYM
dti-2574	102	12	3928	3928	NUM
dti-2574	102	13	www.aboutscience.eu/dti	www.aboutscience.eu/dti	VERB
dti-2574	102	14	vidd	vidd	NOUN
dti-2574	102	15	animals	animal	NOUN
dti-2574	102	16	if	if	SCONJ
dti-2574	102	17	compared	compare	VERB
dti-2574	102	18	to	to	ADP
dti-2574	102	19	healthy	healthy	ADJ
dti-2574	102	20	rats	rat	NOUN
dti-2574	102	21	.	.	PUNCT
dti-2574	103	1	vidd+levo	vidd+levo	PROPN
dti-2574	103	2	group	group	NOUN
dti-2574	103	3	had	have	VERB
dti-2574	103	4	fiber	fiber	NOUN
dti-2574	103	5	diameters	diameter	NOUN
dti-2574	103	6	like	like	ADP
dti-2574	103	7	unventilated	unventilated	ADJ
dti-2574	103	8	animals	animal	NOUN
dti-2574	103	9	.	.	PUNCT
dti-2574	104	1	western	western	ADJ
dti-2574	104	2	blot	blot	NOUN
dti-2574	104	3	analysis	analysis	NOUN
dti-2574	104	4	western	western	ADJ
dti-2574	104	5	blot	blot	NOUN
dti-2574	104	6	analysis	analysis	NOUN
dti-2574	104	7	(	(	PUNCT
dti-2574	104	8	fig	fig	NOUN
dti-2574	104	9	.	.	NOUN
dti-2574	104	10	2	2	NUM
dti-2574	104	11	)	)	PUNCT
dti-2574	104	12	on	on	ADP
dti-2574	104	13	levels	level	NOUN
dti-2574	104	14	of	of	ADP
dti-2574	104	15	proteins	protein	NOUN
dti-2574	104	16	involved	involve	VERB
dti-2574	104	17	in	in	ADP
dti-2574	104	18	muscle	muscle	NOUN
dti-2574	104	19	protein	protein	NOUN
dti-2574	104	20	degradation	degradation	NOUN
dti-2574	104	21	(	(	PUNCT
dti-2574	104	22	atrogin	atrogin	NOUN
dti-2574	104	23	)	)	PUNCT
dti-2574	104	24	did	do	AUX
dti-2574	104	25	not	not	PART
dti-2574	104	26	reveal	reveal	VERB
dti-2574	104	27	any	any	DET
dti-2574	104	28	statistical	statistical	ADJ
dti-2574	104	29	difference	difference	NOUN
dti-2574	104	30	between	between	ADP
dti-2574	104	31	groups	group	NOUN
dti-2574	104	32	.	.	PUNCT
dti-2574	105	1	proteins	protein	NOUN
dti-2574	105	2	implicated	implicate	VERB
dti-2574	105	3	in	in	ADP
dti-2574	105	4	autophagy	autophagy	NOUN
dti-2574	105	5	and	and	CCONJ
dti-2574	105	6	autophagy	autophagy	ADV
dti-2574	105	7	-	-	PUNCT
dti-2574	105	8	related	relate	VERB
dti-2574	105	9	processes	process	NOUN
dti-2574	105	10	(	(	PUNCT
dti-2574	105	11	lc3bi	lc3bi	NOUN
dti-2574	105	12	and	and	CCONJ
dti-2574	105	13	lc3bii	lc3bii	NOUN
dti-2574	105	14	)	)	PUNCT
dti-2574	105	15	were	be	AUX
dti-2574	105	16	significantly	significantly	ADV
dti-2574	105	17	higher	high	ADJ
dti-2574	105	18	in	in	ADP
dti-2574	105	19	the	the	DET
dti-2574	105	20	vidd	vidd	NOUN
dti-2574	105	21	group	group	NOUN
dti-2574	105	22	,	,	PUNCT
dti-2574	105	23	if	if	SCONJ
dti-2574	105	24	compared	compare	VERB
dti-2574	105	25	to	to	ADP
dti-2574	105	26	healthy	healthy	ADJ
dti-2574	105	27	and	and	CCONJ
dti-2574	105	28	vidd+levo	vidd+levo	PROPN
dti-2574	105	29	groups	group	NOUN
dti-2574	105	30	,	,	PUNCT
dti-2574	105	31	while	while	SCONJ
dti-2574	105	32	these	these	DET
dti-2574	105	33	proteins	protein	NOUN
dti-2574	105	34	did	do	AUX
dti-2574	105	35	not	not	PART
dti-2574	105	36	differ	differ	VERB
dti-2574	105	37	in	in	ADP
dti-2574	105	38	the	the	DET
dti-2574	105	39	vidd+levo	vidd+levo	PROPN
dti-2574	105	40	group	group	NOUN
dti-2574	105	41	as	as	SCONJ
dti-2574	105	42	compared	compare	VERB
dti-2574	105	43	with	with	ADP
dti-2574	105	44	the	the	DET
dti-2574	105	45	healthy	healthy	ADJ
dti-2574	105	46	group	group	NOUN
dti-2574	105	47	.	.	PUNCT
dti-2574	106	1	diaphragm	diaphragm	NOUN
dti-2574	106	2	contractile	contractile	NOUN
dti-2574	106	3	dysfunction	dysfunction	NOUN
dti-2574	106	4	after	after	ADP
dti-2574	106	5	5	5	NUM
dti-2574	106	6	hours	hour	NOUN
dti-2574	106	7	of	of	ADP
dti-2574	106	8	mv	mv	PROPN
dti-2574	106	9	,	,	PUNCT
dti-2574	106	10	rats	rat	NOUN
dti-2574	106	11	that	that	PRON
dti-2574	106	12	underwent	undergo	VERB
dti-2574	106	13	ventilation	ventilation	NOUN
dti-2574	106	14	(	(	PUNCT
dti-2574	106	15	vidd	vidd	NOUN
dti-2574	106	16	and	and	CCONJ
dti-2574	106	17	vidd+levo	vidd+levo	PROPN
dti-2574	106	18	)	)	PUNCT
dti-2574	106	19	showed	show	VERB
dti-2574	106	20	a	a	DET
dti-2574	106	21	significant	significant	ADJ
dti-2574	106	22	reduction	reduction	NOUN
dti-2574	106	23	in	in	ADP
dti-2574	106	24	diaphragmatic	diaphragmatic	ADJ
dti-2574	106	25	contractility	contractility	NOUN
dti-2574	106	26	in	in	ADP
dti-2574	106	27	response	response	NOUN
dti-2574	106	28	to	to	ADP
dti-2574	106	29	in	in	ADP
dti-2574	106	30	vitro	vitro	X
dti-2574	106	31	electric	electric	ADJ
dti-2574	106	32	stimulation	stimulation	NOUN
dti-2574	106	33	,	,	PUNCT
dti-2574	106	34	fig	fig	NOUN
dti-2574	106	35	.	.	PUNCT
dti-2574	107	1	3	3	NUM
dti-2574	107	2	diaphragm	diaphragm	NOUN
dti-2574	107	3	contractility	contractility	NOUN
dti-2574	107	4	.	.	PUNCT
dti-2574	108	1	force	force	NOUN
dti-2574	108	2	-	-	PUNCT
dti-2574	108	3	frequency	frequency	NOUN
dti-2574	108	4	relationship	relationship	NOUN
dti-2574	108	5	(	(	PUNCT
dti-2574	108	6	panel	panel	NOUN
dti-2574	108	7	a	a	NOUN
dti-2574	108	8	)	)	PUNCT
dti-2574	108	9	and	and	CCONJ
dti-2574	108	10	peak	peak	VERB
dti-2574	108	11	tetanic	tetanic	ADJ
dti-2574	108	12	tension	tension	NOUN
dti-2574	108	13	(	(	PUNCT
dti-2574	108	14	panel	panel	NOUN
dti-2574	108	15	b	b	NOUN
dti-2574	108	16	)	)	PUNCT
dti-2574	108	17	measured	measure	VERB
dti-2574	108	18	on	on	ADP
dti-2574	108	19	diaphragmatic	diaphragmatic	ADJ
dti-2574	108	20	strips	strip	NOUN
dti-2574	108	21	with	with	ADP
dti-2574	108	22	electric	electric	ADJ
dti-2574	108	23	stimulator	stimulator	NOUN
dti-2574	108	24	at	at	ADP
dti-2574	108	25	the	the	DET
dti-2574	108	26	end	end	NOUN
dti-2574	108	27	of	of	ADP
dti-2574	108	28	the	the	DET
dti-2574	108	29	experiment	experiment	NOUN
dti-2574	108	30	.	.	PUNCT
dti-2574	109	1	a	a	DET
dti-2574	109	2	)	)	PUNCT
dti-2574	109	3	anova	anova	PROPN
dti-2574	110	1	*	*	PUNCT
dti-2574	110	2	p	p	X
dti-2574	110	3	<	<	X
dti-2574	110	4	0.05	0.05	NUM
dti-2574	110	5	,	,	PUNCT
dti-2574	110	6	*	*	PUNCT
dti-2574	110	7	*	*	PUNCT
dti-2574	110	8	p	p	X
dti-2574	110	9	<	<	X
dti-2574	110	10	0.01	0.01	NUM
dti-2574	110	11	.	.	PUNCT
dti-2574	111	1	benjamini	benjamini	PROPN
dti-2574	111	2	,	,	PUNCT
dti-2574	111	3	krieger	krieger	PROPN
dti-2574	111	4	and	and	CCONJ
dti-2574	111	5	yekutieli	yekutieli	ADV
dti-2574	111	6	post	post	VERB
dti-2574	111	7	hoc	hoc	X
dti-2574	111	8	test	test	NOUN
dti-2574	111	9	:	:	PUNCT
dti-2574	111	10	10	10	NUM
dti-2574	111	11	hz	hz	VERB
dti-2574	111	12	p	p	PROPN
dti-2574	111	13	=	=	PROPN
dti-2574	111	14	0.03	0.03	NUM
dti-2574	111	15	vs.	vs.	ADP
dti-2574	111	16	vidd	vidd	NOUN
dti-2574	111	17	and	and	CCONJ
dti-2574	111	18	vs.	vs.	ADP
dti-2574	111	19	vidd+levo	vidd+levo	PROPN
dti-2574	111	20	,	,	PUNCT
dti-2574	111	21	30	30	NUM
dti-2574	111	22	hz	hz	VERB
dti-2574	111	23	p	p	NOUN
dti-2574	111	24	=	=	PROPN
dti-2574	111	25	0.001	0.001	NUM
dti-2574	111	26	vs.	vs.	ADP
dti-2574	111	27	vidd	vidd	NOUN
dti-2574	111	28	and	and	CCONJ
dti-2574	111	29	p	p	NOUN
dti-2574	111	30	=	=	NOUN
dti-2574	111	31	0.004	0.004	NUM
dti-2574	111	32	vs.	vs.	ADP
dti-2574	111	33	vidd+levo	vidd+levo	NOUN
dti-2574	111	34	,	,	PUNCT
dti-2574	111	35	60	60	NUM
dti-2574	111	36	hz	hz	VERB
dti-2574	111	37	p	p	PROPN
dti-2574	111	38	=	=	PROPN
dti-2574	111	39	0.002	0.002	NUM
dti-2574	111	40	vs.	vs.	ADP
dti-2574	111	41	vidd	vidd	NOUN
dti-2574	111	42	and	and	CCONJ
dti-2574	111	43	p	p	NOUN
dti-2574	111	44	=	=	NOUN
dti-2574	111	45	0.005	0.005	NUM
dti-2574	111	46	vs.	vs.	ADP
dti-2574	111	47	vidd+levo	vidd+levo	PROPN
dti-2574	111	48	,	,	PUNCT
dti-2574	111	49	90	90	NUM
dti-2574	111	50	hz	hz	VERB
dti-2574	111	51	p	p	NOUN
dti-2574	111	52	=	=	NOUN
dti-2574	111	53	0.004	0.004	NUM
dti-2574	111	54	vs.	vs.	ADP
dti-2574	111	55	vidd	vidd	NOUN
dti-2574	111	56	and	and	CCONJ
dti-2574	111	57	p	p	NOUN
dti-2574	111	58	=	=	NOUN
dti-2574	111	59	0.01	0.01	NUM
dti-2574	111	60	vs.	vs.	ADP
dti-2574	111	61	vidd+levo	vidd+levo	NOUN
dti-2574	111	62	,	,	PUNCT
dti-2574	111	63	120	120	NUM
dti-2574	111	64	hz	hz	VERB
dti-2574	111	65	p	p	NOUN
dti-2574	111	66	=	=	PROPN
dti-2574	111	67	0.006	0.006	NUM
dti-2574	111	68	vs.	vs.	ADP
dti-2574	111	69	vidd	vidd	NOUN
dti-2574	111	70	and	and	CCONJ
dti-2574	111	71	p	p	NOUN
dti-2574	111	72	=	=	NOUN
dti-2574	111	73	0.01	0.01	NUM
dti-2574	111	74	vs.	vs.	ADP
dti-2574	111	75	vidd+levo	vidd+levo	NOUN
dti-2574	111	76	,	,	PUNCT
dti-2574	111	77	150	150	NUM
dti-2574	111	78	hz	hz	VERB
dti-2574	111	79	p	p	NOUN
dti-2574	111	80	=	=	PROPN
dti-2574	111	81	0.007	0.007	NUM
dti-2574	111	82	vs.	vs.	ADP
dti-2574	111	83	vidd	vidd	NOUN
dti-2574	111	84	and	and	CCONJ
dti-2574	111	85	p	p	NOUN
dti-2574	111	86	=	=	PROPN
dti-2574	111	87	0.002	0.002	NUM
dti-2574	111	88	vs.	vs.	ADP
dti-2574	111	89	vidd+levo	vidd+levo	PROPN
dti-2574	111	90	.	.	PUNCT
dti-2574	112	1	b	b	X
dti-2574	112	2	)	)	PUNCT
dti-2574	112	3	anova	anova	PROPN
dti-2574	113	1	p	p	X
dti-2574	113	2	<	<	X
dti-2574	113	3	0.05	0.05	NUM
dti-2574	113	4	.	.	PUNCT
dti-2574	114	1	anova	anova	PROPN
dti-2574	115	1	=	=	PUNCT
dti-2574	115	2	analysis	analysis	NOUN
dti-2574	115	3	of	of	ADP
dti-2574	115	4	variance	variance	NOUN
dti-2574	115	5	;	;	PUNCT
dti-2574	115	6	vidd	vidd	NOUN
dti-2574	115	7	=	=	SYM
dti-2574	115	8	ventilatorinduced	ventilatorinduce	VERB
dti-2574	115	9	diaphragmatic	diaphragmatic	ADJ
dti-2574	115	10	dysfunction	dysfunction	NOUN
dti-2574	115	11	.	.	PUNCT
dti-2574	116	1	b	b	X
dti-2574	116	2	)	)	PUNCT
dti-2574	116	3	anova	anova	PROPN
dti-2574	117	1	p	p	X
dti-2574	117	2	<	<	X
dti-2574	117	3	0.05	0.05	NUM
dti-2574	117	4	.	.	PUNCT
dti-2574	117	5	benjamini	benjamini	PROPN
dti-2574	117	6	,	,	PUNCT
dti-2574	117	7	krieger	krieger	PROPN
dti-2574	117	8	and	and	CCONJ
dti-2574	117	9	yekutieli	yekutieli	ADV
dti-2574	117	10	post	post	ADJ
dti-2574	117	11	-	-	ADJ
dti-2574	117	12	hoc	hoc	ADJ
dti-2574	117	13	test	test	NOUN
dti-2574	117	14	:	:	PUNCT
dti-2574	118	1	p	p	X
dti-2574	118	2	=	=	PUNCT
dti-2574	118	3	0.007	0.007	NUM
dti-2574	118	4	vs	vs	ADP
dti-2574	118	5	vidd	vidd	NOUN
dti-2574	118	6	,	,	PUNCT
dti-2574	118	7	p	p	NOUN
dti-2574	118	8	=	=	NOUN
dti-2574	118	9	0.01	0.01	NUM
dti-2574	118	10	vs	vs	ADP
dti-2574	118	11	vidd+levo	vidd+levo	PROPN
dti-2574	118	12	.	.	PUNCT
dti-2574	119	1	healthy	healthy	ADJ
dti-2574	119	2	:	:	PUNCT
dti-2574	120	1	no	no	DET
dti-2574	120	2	surgical	surgical	ADJ
dti-2574	120	3	interventions	intervention	NOUN
dti-2574	120	4	,	,	PUNCT
dti-2574	120	5	no	no	DET
dti-2574	120	6	mv	mv	NOUN
dti-2574	120	7	,	,	PUNCT
dti-2574	120	8	and	and	CCONJ
dti-2574	120	9	no	no	DET
dti-2574	120	10	treatment	treatment	NOUN
dti-2574	120	11	(	(	PUNCT
dti-2574	120	12	n	n	NOUN
dti-2574	120	13	=	=	SYM
dti-2574	120	14	8)	8)	NUM
dti-2574	120	15	;	;	PUNCT
dti-2574	120	16	vidd	vidd	NOUN
dti-2574	120	17	:	:	PUNCT
dti-2574	120	18	surgical	surgical	ADJ
dti-2574	120	19	intervention	intervention	NOUN
dti-2574	120	20	+	+	CCONJ
dti-2574	120	21	mv	mv	PROPN
dti-2574	120	22	and	and	CCONJ
dti-2574	120	23	no	no	DET
dti-2574	120	24	treatment	treatment	NOUN
dti-2574	120	25	(	(	PUNCT
dti-2574	120	26	n	n	NOUN
dti-2574	120	27	=	=	NUM
dti-2574	120	28	12	12	NUM
dti-2574	120	29	)	)	PUNCT
dti-2574	120	30	;	;	PUNCT
dti-2574	120	31	vidd+levo	vidd+levo	NOUN
dti-2574	120	32	:	:	PUNCT
dti-2574	120	33	surgical	surgical	ADJ
dti-2574	120	34	intervention	intervention	NOUN
dti-2574	120	35	+	+	CCONJ
dti-2574	120	36	mv	mv	PROPN
dti-2574	120	37	+	+	CCONJ
dti-2574	120	38	levosimendan	levosimendan	PROPN
dti-2574	120	39	treatment	treatment	NOUN
dti-2574	120	40	(	(	PUNCT
dti-2574	120	41	n	n	NOUN
dti-2574	120	42	=	=	SYM
dti-2574	120	43	8)	8)	NUM
dti-2574	120	44	.	.	PUNCT
dti-2574	121	1	in	in	ADP
dti-2574	121	2	comparison	comparison	NOUN
dti-2574	121	3	to	to	ADP
dti-2574	121	4	unventilated	unventilated	ADJ
dti-2574	121	5	animals	animal	NOUN
dti-2574	121	6	.	.	PUNCT
dti-2574	122	1	as	as	SCONJ
dti-2574	122	2	demonstrated	demonstrate	VERB
dti-2574	122	3	in	in	ADP
dti-2574	122	4	figure	figure	NOUN
dti-2574	122	5	3a	3a	NUM
dti-2574	122	6	,	,	PUNCT
dti-2574	122	7	increasing	increase	VERB
dti-2574	122	8	the	the	DET
dti-2574	122	9	frequency	frequency	NOUN
dti-2574	122	10	of	of	ADP
dti-2574	122	11	stimulation	stimulation	NOUN
dti-2574	122	12	the	the	DET
dti-2574	122	13	diaphragmatic	diaphragmatic	ADJ
dti-2574	122	14	muscle	muscle	NOUN
dti-2574	122	15	strip	strip	NOUN
dti-2574	122	16	of	of	ADP
dti-2574	122	17	ventilated	ventilate	VERB
dti-2574	122	18	rats	rat	NOUN
dti-2574	122	19	generated	generate	VERB
dti-2574	122	20	less	less	ADJ
dti-2574	122	21	force	force	NOUN
dti-2574	122	22	than	than	ADP
dti-2574	122	23	the	the	DET
dti-2574	122	24	healthy	healthy	ADJ
dti-2574	122	25	diaphragm	diaphragm	NOUN
dti-2574	122	26	.	.	PUNCT
dti-2574	123	1	levosimendan	levosimendan	PROPN
dti-2574	123	2	treatment	treatment	PROPN
dti-2574	123	3	did	do	AUX
dti-2574	123	4	not	not	PART
dti-2574	123	5	affect	affect	VERB
dti-2574	123	6	the	the	DET
dti-2574	123	7	diaphragmatic	diaphragmatic	ADJ
dti-2574	123	8	contractility	contractility	NOUN
dti-2574	123	9	.	.	PUNCT
dti-2574	124	1	the	the	DET
dti-2574	124	2	analysis	analysis	NOUN
dti-2574	124	3	of	of	ADP
dti-2574	124	4	peak	peak	ADJ
dti-2574	124	5	tetanic	tetanic	ADJ
dti-2574	124	6	tension	tension	NOUN
dti-2574	124	7	unveiled	unveil	VERB
dti-2574	124	8	that	that	SCONJ
dti-2574	124	9	ventilated	ventilate	VERB
dti-2574	124	10	rats	rat	NOUN
dti-2574	124	11	(	(	PUNCT
dti-2574	124	12	with	with	ADP
dti-2574	124	13	or	or	CCONJ
dti-2574	124	14	without	without	ADP
dti-2574	124	15	levosimendan	levosimendan	PROPN
dti-2574	124	16	treatment	treatment	PROPN
dti-2574	124	17	)	)	PUNCT
dti-2574	124	18	showed	show	VERB
dti-2574	124	19	a	a	DET
dti-2574	124	20	similar	similar	ADJ
dti-2574	124	21	diaphragmatic	diaphragmatic	ADJ
dti-2574	124	22	muscular	muscular	ADJ
dti-2574	124	23	contractility	contractility	NOUN
dti-2574	124	24	(	(	PUNCT
dti-2574	124	25	fig	fig	NOUN
dti-2574	124	26	.	.	PUNCT
dti-2574	125	1	3b	3b	NUM
dti-2574	125	2	)	)	PUNCT
dti-2574	125	3	.	.	PUNCT
dti-2574	126	1	discussion	discussion	NOUN
dti-2574	126	2	in	in	ADP
dti-2574	126	3	this	this	DET
dti-2574	126	4	experimental	experimental	ADJ
dti-2574	126	5	model	model	NOUN
dti-2574	126	6	of	of	ADP
dti-2574	126	7	vidd	vidd	NOUN
dti-2574	126	8	,	,	PUNCT
dti-2574	126	9	after	after	ADP
dti-2574	126	10	5	5	NUM
dti-2574	126	11	hours	hour	NOUN
dti-2574	126	12	of	of	ADP
dti-2574	126	13	mv	mv	PROPN
dti-2574	126	14	in	in	ADP
dti-2574	126	15	a	a	DET
dti-2574	126	16	rat	rat	NOUN
dti-2574	126	17	model	model	NOUN
dti-2574	126	18	of	of	ADP
dti-2574	126	19	vidd	vidd	NOUN
dti-2574	126	20	as	as	SCONJ
dti-2574	126	21	compared	compare	VERB
dti-2574	126	22	to	to	ADP
dti-2574	126	23	control	control	VERB
dti-2574	126	24	,	,	PUNCT
dti-2574	126	25	our	our	PRON
dti-2574	126	26	data	datum	NOUN
dti-2574	126	27	suggest	suggest	VERB
dti-2574	126	28	that	that	SCONJ
dti-2574	126	29	the	the	DET
dti-2574	126	30	administration	administration	NOUN
dti-2574	126	31	of	of	ADP
dti-2574	126	32	levosimendan	levosimendan	PROPN
dti-2574	126	33	:	:	PUNCT
dti-2574	126	34	fig	fig	NOUN
dti-2574	126	35	.	.	NOUN
dti-2574	126	36	2	2	NUM
dti-2574	126	37	western	western	ADJ
dti-2574	126	38	blot	blot	NOUN
dti-2574	126	39	analysis	analysis	NOUN
dti-2574	126	40	.	.	PUNCT
dti-2574	127	1	atrogin	atrogin	NOUN
dti-2574	127	2	and	and	CCONJ
dti-2574	127	3	lc3bii	lc3bii	PROPN
dti-2574	127	4	/	/	SYM
dti-2574	127	5	lc3bi	lc3bi	NOUN
dti-2574	127	6	levels	level	NOUN
dti-2574	127	7	on	on	ADP
dti-2574	127	8	diaphragm	diaphragm	NOUN
dti-2574	127	9	tissue	tissue	NOUN
dti-2574	127	10	.	.	PUNCT
dti-2574	128	1	a	a	PRON
dti-2574	128	2	)	)	PUNCT
dti-2574	128	3	anova	anova	PROPN
dti-2574	129	1	p	p	X
dti-2574	130	1	=	=	PROPN
dti-2574	131	1	0.21	0.21	NUM
dti-2574	131	2	.	.	PUNCT
dti-2574	132	1	b	b	X
dti-2574	132	2	)	)	PUNCT
dti-2574	132	3	anova	anova	PROPN
dti-2574	133	1	p	p	X
dti-2574	133	2	=	=	PROPN
dti-2574	133	3	0.03	0.03	NUM
dti-2574	133	4	.	.	PUNCT
dti-2574	133	5	benjamini	benjamini	PROPN
dti-2574	133	6	,	,	PUNCT
dti-2574	133	7	krieger	krieger	PROPN
dti-2574	133	8	and	and	CCONJ
dti-2574	133	9	yekutieli	yekutieli	ADV
dti-2574	133	10	post	post	VERB
dti-2574	133	11	hoc	hoc	X
dti-2574	133	12	test	test	NOUN
dti-2574	133	13	:	:	PUNCT
dti-2574	134	1	p	p	X
dti-2574	134	2	=	=	PUNCT
dti-2574	134	3	0.02	0.02	NUM
dti-2574	134	4	vs.	vs.	ADP
dti-2574	134	5	healthy	healthy	ADJ
dti-2574	134	6	and	and	CCONJ
dti-2574	134	7	p	p	X
dti-2574	134	8	=	=	PROPN
dti-2574	134	9	0.04	0.04	NUM
dti-2574	134	10	vs.	vs.	ADP
dti-2574	134	11	vidd+levo	vidd+levo	PROPN
dti-2574	134	12	.	.	PUNCT
dti-2574	135	1	healthy	healthy	ADJ
dti-2574	135	2	:	:	PUNCT
dti-2574	136	1	no	no	DET
dti-2574	136	2	surgical	surgical	ADJ
dti-2574	136	3	interventions	intervention	NOUN
dti-2574	136	4	,	,	PUNCT
dti-2574	136	5	no	no	DET
dti-2574	136	6	mv	mv	NOUN
dti-2574	136	7	,	,	PUNCT
dti-2574	136	8	and	and	CCONJ
dti-2574	136	9	no	no	DET
dti-2574	136	10	treatment	treatment	NOUN
dti-2574	136	11	(	(	PUNCT
dti-2574	136	12	n	n	NOUN
dti-2574	136	13	=	=	SYM
dti-2574	136	14	8)	8)	NUM
dti-2574	136	15	;	;	PUNCT
dti-2574	136	16	vidd	vidd	NOUN
dti-2574	136	17	:	:	PUNCT
dti-2574	136	18	surgical	surgical	ADJ
dti-2574	136	19	intervention	intervention	NOUN
dti-2574	136	20	+	+	CCONJ
dti-2574	136	21	mv	mv	PROPN
dti-2574	136	22	and	and	CCONJ
dti-2574	136	23	no	no	DET
dti-2574	136	24	treatment	treatment	NOUN
dti-2574	136	25	(	(	PUNCT
dti-2574	136	26	n	n	NOUN
dti-2574	136	27	=	=	NUM
dti-2574	136	28	11	11	NUM
dti-2574	136	29	)	)	PUNCT
dti-2574	136	30	;	;	PUNCT
dti-2574	136	31	vidd+levo	vidd+levo	NOUN
dti-2574	136	32	:	:	PUNCT
dti-2574	136	33	surgical	surgical	ADJ
dti-2574	136	34	intervention	intervention	NOUN
dti-2574	136	35	+	+	CCONJ
dti-2574	136	36	mv	mv	PROPN
dti-2574	136	37	+	+	CCONJ
dti-2574	136	38	levosimendan	levosimendan	PROPN
dti-2574	136	39	treatment	treatment	NOUN
dti-2574	136	40	(	(	PUNCT
dti-2574	136	41	n	n	NOUN
dti-2574	136	42	=	=	SYM
dti-2574	136	43	8)	8)	NUM
dti-2574	136	44	.	.	PUNCT
dti-2574	136	45	anova	anova	PROPN
dti-2574	137	1	=	=	PUNCT
dti-2574	137	2	analysis	analysis	NOUN
dti-2574	137	3	of	of	ADP
dti-2574	137	4	variance	variance	NOUN
dti-2574	137	5	;	;	PUNCT
dti-2574	137	6	mv	mv	PROPN
dti-2574	137	7	=	=	NOUN
dti-2574	137	8	mechanical	mechanical	ADJ
dti-2574	137	9	ventilation	ventilation	NOUN
dti-2574	137	10	;	;	PUNCT
dti-2574	137	11	vidd	vidd	NOUN
dti-2574	137	12	=	=	SYM
dti-2574	137	13	ventilator	ventilator	NOUN
dti-2574	137	14	-	-	PUNCT
dti-2574	137	15	induced	induce	VERB
dti-2574	137	16	diaphragmatic	diaphragmatic	ADJ
dti-2574	137	17	dysfunction	dysfunction	NOUN
dti-2574	137	18	.	.	PUNCT
dti-2574	138	1	zambelli	zambelli	PROPN
dti-2574	138	2	et	et	PROPN
dti-2574	138	3	al	al	PROPN
dti-2574	138	4	drug	drug	PROPN
dti-2574	138	5	target	target	NOUN
dti-2574	138	6	insights	insight	NOUN
dti-2574	138	7	2023	2023	NUM
dti-2574	138	8	;	;	PUNCT
dti-2574	138	9	17	17	NUM
dti-2574	138	10	:	:	SYM
dti-2574	138	11	43	43	NUM
dti-2574	138	12	©	©	PROPN
dti-2574	138	13	2023	2023	NUM
dti-2574	138	14	the	the	DET
dti-2574	138	15	authors	author	NOUN
dti-2574	138	16	.	.	PUNCT
dti-2574	139	1	published	publish	VERB
dti-2574	139	2	by	by	ADP
dti-2574	139	3	aboutscience	aboutscience	NOUN
dti-2574	139	4	www.aboutscience.eu	www.aboutscience.eu	NOUN
dti-2574	139	5	1	1	NUM
dti-2574	139	6	.	.	PUNCT
dti-2574	140	1	preserves	preserve	VERB
dti-2574	140	2	the	the	DET
dti-2574	140	3	diaphragm	diaphragm	PROPN
dti-2574	140	4	muscular	muscular	ADJ
dti-2574	140	5	cell	cell	NOUN
dti-2574	140	6	structure	structure	NOUN
dti-2574	140	7	;	;	PUNCT
dti-2574	140	8	2	2	X
dti-2574	140	9	.	.	NOUN
dti-2574	140	10	reduces	reduce	VERB
dti-2574	140	11	autophagy	autophagy	ADV
dti-2574	140	12	-	-	PUNCT
dti-2574	140	13	implicated	implicate	VERB
dti-2574	140	14	proteins	protein	NOUN
dti-2574	140	15	of	of	ADP
dti-2574	140	16	the	the	DET
dti-2574	140	17	diaphragm	diaphragm	NOUN
dti-2574	140	18	muscle	muscle	NOUN
dti-2574	140	19	cells	cell	NOUN
dti-2574	140	20	;	;	PUNCT
dti-2574	140	21	3	3	X
dti-2574	140	22	.	.	X
dti-2574	140	23	does	do	AUX
dti-2574	140	24	not	not	PART
dti-2574	140	25	affect	affect	VERB
dti-2574	140	26	diaphragm	diaphragm	NOUN
dti-2574	140	27	contractile	contractile	NOUN
dti-2574	140	28	function	function	NOUN
dti-2574	140	29	.	.	PUNCT
dti-2574	141	1	levosimendan	levosimendan	PROPN
dti-2574	141	2	is	be	AUX
dti-2574	141	3	a	a	DET
dti-2574	141	4	calcium	calcium	NOUN
dti-2574	141	5	-	-	PUNCT
dti-2574	141	6	sensitizing	sensitize	VERB
dti-2574	141	7	inodilator	inodilator	NOUN
dti-2574	141	8	widely	widely	ADV
dti-2574	141	9	used	use	VERB
dti-2574	141	10	in	in	ADP
dti-2574	141	11	the	the	DET
dti-2574	141	12	management	management	NOUN
dti-2574	141	13	of	of	ADP
dti-2574	141	14	acutely	acutely	ADV
dti-2574	141	15	decompensated	decompensate	VERB
dti-2574	141	16	chronic	chronic	ADJ
dti-2574	141	17	heart	heart	NOUN
dti-2574	141	18	failure	failure	NOUN
dti-2574	141	19	from	from	ADP
dti-2574	141	20	over	over	ADP
dti-2574	141	21	20	20	NUM
dti-2574	141	22	years	year	NOUN
dti-2574	141	23	.	.	PUNCT
dti-2574	142	1	in	in	ADP
dti-2574	142	2	addition	addition	NOUN
dti-2574	142	3	,	,	PUNCT
dti-2574	142	4	it	it	PRON
dti-2574	142	5	has	have	AUX
dti-2574	142	6	been	be	AUX
dti-2574	142	7	evaluated	evaluate	VERB
dti-2574	142	8	in	in	ADP
dti-2574	142	9	a	a	DET
dti-2574	142	10	variety	variety	NOUN
dti-2574	142	11	of	of	ADP
dti-2574	142	12	clinical	clinical	ADJ
dti-2574	142	13	settings	setting	NOUN
dti-2574	142	14	for	for	ADP
dti-2574	142	15	both	both	CCONJ
dti-2574	142	16	cardiac	cardiac	ADJ
dti-2574	142	17	and	and	CCONJ
dti-2574	142	18	non	non	ADJ
dti-2574	142	19	-	-	ADJ
dti-2574	142	20	cardiac	cardiac	ADJ
dti-2574	142	21	disease	disease	NOUN
dti-2574	142	22	(	(	PUNCT
dti-2574	142	23	24,25	24,25	NUM
dti-2574	142	24	)	)	PUNCT
dti-2574	142	25	.	.	PUNCT
dti-2574	143	1	one	one	NUM
dti-2574	143	2	possible	possible	ADJ
dti-2574	143	3	area	area	NOUN
dti-2574	143	4	of	of	ADP
dti-2574	143	5	investigation	investigation	NOUN
dti-2574	143	6	is	be	AUX
dti-2574	143	7	respiratory	respiratory	ADJ
dti-2574	143	8	muscle	muscle	NOUN
dti-2574	143	9	dysfunction	dysfunction	NOUN
dti-2574	143	10	,	,	PUNCT
dti-2574	143	11	because	because	SCONJ
dti-2574	143	12	,	,	PUNCT
dti-2574	143	13	in	in	ADP
dti-2574	143	14	addition	addition	NOUN
dti-2574	143	15	to	to	ADP
dti-2574	143	16	cellular	cellular	ADJ
dti-2574	143	17	atrophy	atrophy	NOUN
dti-2574	143	18	,	,	PUNCT
dti-2574	143	19	reduced	reduce	VERB
dti-2574	143	20	calcium	calcium	NOUN
dti-2574	143	21	sensitivity	sensitivity	NOUN
dti-2574	143	22	of	of	ADP
dti-2574	143	23	contraction	contraction	NOUN
dti-2574	143	24	causes	cause	VERB
dti-2574	143	25	respiratory	respiratory	ADJ
dti-2574	143	26	muscle	muscle	NOUN
dti-2574	143	27	weakness	weakness	NOUN
dti-2574	143	28	(	(	PUNCT
dti-2574	143	29	26	26	NUM
dti-2574	143	30	)	)	PUNCT
dti-2574	143	31	.	.	PUNCT
dti-2574	144	1	in	in	ADP
dti-2574	144	2	vitro	vitro	X
dti-2574	144	3	studies	study	NOUN
dti-2574	144	4	on	on	ADP
dti-2574	144	5	isolated	isolated	ADJ
dti-2574	144	6	muscle	muscle	NOUN
dti-2574	144	7	fibers	fiber	NOUN
dti-2574	144	8	showed	show	VERB
dti-2574	144	9	that	that	SCONJ
dti-2574	144	10	levosimendan	levosimendan	PROPN
dti-2574	144	11	increased	increase	VERB
dti-2574	144	12	force	force	NOUN
dti-2574	144	13	-	-	PUNCT
dti-2574	144	14	generating	generate	VERB
dti-2574	144	15	capacity	capacity	NOUN
dti-2574	144	16	of	of	ADP
dti-2574	144	17	diaphragm	diaphragm	NOUN
dti-2574	144	18	from	from	ADP
dti-2574	144	19	copd	copd	PROPN
dti-2574	144	20	and	and	CCONJ
dti-2574	144	21	non	non	ADJ
dti-2574	144	22	-	-	ADJ
dti-2574	144	23	copd	copd	ADJ
dti-2574	144	24	patients	patient	NOUN
dti-2574	144	25	by	by	ADP
dti-2574	144	26	improving	improve	VERB
dti-2574	144	27	calcium	calcium	NOUN
dti-2574	144	28	sensitivity	sensitivity	NOUN
dti-2574	144	29	of	of	ADP
dti-2574	144	30	force	force	NOUN
dti-2574	144	31	generation	generation	NOUN
dti-2574	144	32	(	(	PUNCT
dti-2574	144	33	17	17	NUM
dti-2574	144	34	)	)	PUNCT
dti-2574	144	35	.	.	PUNCT
dti-2574	145	1	clinical	clinical	ADJ
dti-2574	145	2	studies	study	NOUN
dti-2574	145	3	have	have	AUX
dti-2574	145	4	produced	produce	VERB
dti-2574	145	5	mixed	mixed	ADJ
dti-2574	145	6	results	result	NOUN
dti-2574	145	7	,	,	PUNCT
dti-2574	145	8	the	the	DET
dti-2574	145	9	same	same	ADJ
dti-2574	145	10	investigators	investigator	NOUN
dti-2574	145	11	discovered	discover	VERB
dti-2574	145	12	that	that	SCONJ
dti-2574	145	13	levosimendan	levosimendan	PROPN
dti-2574	145	14	increased	increase	VERB
dti-2574	145	15	in	in	ADP
dti-2574	145	16	vivo	vivo	ADJ
dti-2574	145	17	diaphragmatic	diaphragmatic	ADJ
dti-2574	145	18	contractile	contractile	NOUN
dti-2574	145	19	efficiency	efficiency	NOUN
dti-2574	145	20	in	in	ADP
dti-2574	145	21	healthy	healthy	ADJ
dti-2574	145	22	participants	participant	NOUN
dti-2574	145	23	(	(	PUNCT
dti-2574	145	24	27	27	NUM
dti-2574	145	25	)	)	PUNCT
dti-2574	145	26	,	,	PUNCT
dti-2574	145	27	while	while	SCONJ
dti-2574	145	28	it	it	PRON
dti-2574	145	29	had	have	VERB
dti-2574	145	30	no	no	DET
dti-2574	145	31	effect	effect	NOUN
dti-2574	145	32	on	on	ADP
dti-2574	145	33	diaphragm	diaphragm	NOUN
dti-2574	145	34	function	function	NOUN
dti-2574	145	35	in	in	ADP
dti-2574	145	36	intensive	intensive	ADJ
dti-2574	145	37	care	care	NOUN
dti-2574	145	38	unit	unit	NOUN
dti-2574	145	39	(	(	PUNCT
dti-2574	145	40	icu	icu	PROPN
dti-2574	145	41	)	)	PUNCT
dti-2574	145	42	patients	patient	NOUN
dti-2574	145	43	(	(	PUNCT
dti-2574	145	44	28	28	NUM
dti-2574	145	45	)	)	PUNCT
dti-2574	145	46	.	.	PUNCT
dti-2574	146	1	the	the	DET
dti-2574	146	2	role	role	NOUN
dti-2574	146	3	of	of	ADP
dti-2574	146	4	levosimendan	levosimendan	PROPN
dti-2574	146	5	as	as	ADP
dti-2574	146	6	potential	potential	ADJ
dti-2574	146	7	therapeutic	therapeutic	ADJ
dti-2574	146	8	intervention	intervention	NOUN
dti-2574	146	9	of	of	ADP
dti-2574	146	10	diaphragm	diaphragm	NOUN
dti-2574	146	11	dysfunction	dysfunction	NOUN
dti-2574	146	12	is	be	AUX
dti-2574	146	13	an	an	DET
dti-2574	146	14	open	open	ADJ
dti-2574	146	15	field	field	NOUN
dti-2574	146	16	of	of	ADP
dti-2574	146	17	current	current	ADJ
dti-2574	146	18	pharmacological	pharmacological	ADJ
dti-2574	146	19	research	research	NOUN
dti-2574	146	20	for	for	ADP
dti-2574	146	21	vidd	vidd	NOUN
dti-2574	146	22	in	in	ADP
dti-2574	146	23	addition	addition	NOUN
dti-2574	146	24	to	to	ADP
dti-2574	146	25	the	the	DET
dti-2574	146	26	one	one	NOUN
dti-2574	146	27	for	for	ADP
dti-2574	146	28	vili	vili	NOUN
dti-2574	146	29	because	because	SCONJ
dti-2574	146	30	of	of	ADP
dti-2574	146	31	the	the	DET
dti-2574	146	32	need	need	NOUN
dti-2574	146	33	of	of	ADP
dti-2574	146	34	mv	mv	PROPN
dti-2574	146	35	in	in	ADP
dti-2574	146	36	the	the	DET
dti-2574	146	37	presence	presence	NOUN
dti-2574	146	38	of	of	ADP
dti-2574	146	39	severe	severe	ADJ
dti-2574	146	40	respiratory	respiratory	ADJ
dti-2574	146	41	failure	failure	NOUN
dti-2574	146	42	(	(	PUNCT
dti-2574	146	43	3,29	3,29	NUM
dti-2574	146	44	)	)	PUNCT
dti-2574	146	45	.	.	PUNCT
dti-2574	147	1	in	in	ADP
dti-2574	147	2	this	this	DET
dti-2574	147	3	study	study	NOUN
dti-2574	147	4	we	we	PRON
dti-2574	147	5	evaluated	evaluate	VERB
dti-2574	147	6	the	the	DET
dti-2574	147	7	effects	effect	NOUN
dti-2574	147	8	of	of	ADP
dti-2574	147	9	levosimendan	levosimendan	ADJ
dti-2574	147	10	treatment	treatment	NOUN
dti-2574	147	11	in	in	ADP
dti-2574	147	12	preclinical	preclinical	NOUN
dti-2574	147	13	in	in	ADP
dti-2574	147	14	vivo	vivo	ADJ
dti-2574	147	15	rodent	rodent	NOUN
dti-2574	147	16	model	model	NOUN
dti-2574	147	17	of	of	ADP
dti-2574	147	18	vidd	vidd	NOUN
dti-2574	147	19	.	.	PUNCT
dti-2574	148	1	we	we	PRON
dti-2574	148	2	have	have	AUX
dti-2574	148	3	previously	previously	ADV
dti-2574	148	4	demonstrated	demonstrate	VERB
dti-2574	148	5	that	that	SCONJ
dti-2574	148	6	the	the	DET
dti-2574	148	7	model	model	NOUN
dti-2574	148	8	resembles	resemble	VERB
dti-2574	148	9	the	the	DET
dti-2574	148	10	main	main	ADJ
dti-2574	148	11	features	feature	NOUN
dti-2574	148	12	of	of	ADP
dti-2574	148	13	diaphragmatic	diaphragmatic	ADJ
dti-2574	148	14	dysfunction	dysfunction	NOUN
dti-2574	148	15	(	(	PUNCT
dti-2574	148	16	22	22	NUM
dti-2574	148	17	)	)	PUNCT
dti-2574	148	18	.	.	PUNCT
dti-2574	149	1	as	as	SCONJ
dti-2574	149	2	levosimendan	levosimendan	PROPN
dti-2574	149	3	has	have	VERB
dti-2574	149	4	a	a	DET
dti-2574	149	5	short	short	ADJ
dti-2574	149	6	half	half	ADJ
dti-2574	149	7	-	-	PUNCT
dti-2574	149	8	life	life	NOUN
dti-2574	149	9	of	of	ADP
dti-2574	149	10	1	1	NUM
dti-2574	149	11	hour	hour	NOUN
dti-2574	149	12	,	,	PUNCT
dti-2574	149	13	a	a	DET
dti-2574	149	14	bolus	bolus	NOUN
dti-2574	149	15	of	of	ADP
dti-2574	149	16	24	24	NUM
dti-2574	149	17	µg/	µg/	NOUN
dti-2574	149	18	kg	kg	NOUN
dti-2574	149	19	was	be	AUX
dti-2574	149	20	immediately	immediately	ADV
dti-2574	149	21	administered	administer	VERB
dti-2574	149	22	after	after	ADP
dti-2574	149	23	orotracheal	orotracheal	ADJ
dti-2574	149	24	intubation	intubation	NOUN
dti-2574	149	25	and	and	CCONJ
dti-2574	149	26	mv	mv	NOUN
dti-2574	149	27	.	.	PUNCT
dti-2574	150	1	it	it	PRON
dti-2574	150	2	is	be	AUX
dti-2574	150	3	well	well	ADV
dti-2574	150	4	known	know	VERB
dti-2574	150	5	that	that	SCONJ
dti-2574	150	6	the	the	DET
dti-2574	150	7	use	use	NOUN
dti-2574	150	8	of	of	ADP
dti-2574	150	9	a	a	DET
dti-2574	150	10	bolus	bolus	ADJ
dti-2574	150	11	dose	dose	NOUN
dti-2574	150	12	should	should	AUX
dti-2574	150	13	be	be	AUX
dti-2574	150	14	avoided	avoid	VERB
dti-2574	150	15	due	due	ADP
dti-2574	150	16	to	to	ADP
dti-2574	150	17	the	the	DET
dti-2574	150	18	risk	risk	NOUN
dti-2574	150	19	of	of	ADP
dti-2574	150	20	hypotension	hypotension	NOUN
dti-2574	150	21	(	(	PUNCT
dti-2574	150	22	30	30	NUM
dti-2574	150	23	)	)	PUNCT
dti-2574	150	24	,	,	PUNCT
dti-2574	150	25	but	but	CCONJ
dti-2574	150	26	the	the	DET
dti-2574	150	27	animals	animal	NOUN
dti-2574	150	28	in	in	ADP
dti-2574	150	29	this	this	DET
dti-2574	150	30	study	study	NOUN
dti-2574	150	31	were	be	AUX
dti-2574	150	32	healthy	healthy	ADJ
dti-2574	150	33	at	at	ADP
dti-2574	150	34	the	the	DET
dti-2574	150	35	beginning	beginning	NOUN
dti-2574	150	36	of	of	ADP
dti-2574	150	37	the	the	DET
dti-2574	150	38	study	study	NOUN
dti-2574	150	39	with	with	ADP
dti-2574	150	40	physiological	physiological	ADJ
dti-2574	150	41	hemodynamics	hemodynamic	NOUN
dti-2574	150	42	,	,	PUNCT
dti-2574	150	43	as	as	SCONJ
dti-2574	150	44	shown	show	VERB
dti-2574	150	45	in	in	ADP
dti-2574	150	46	table	table	NOUN
dti-2574	150	47	i.	i.	NOUN
dti-2574	150	48	in	in	ADP
dti-2574	150	49	our	our	PRON
dti-2574	150	50	experimental	experimental	ADJ
dti-2574	150	51	design	design	NOUN
dti-2574	150	52	,	,	PUNCT
dti-2574	150	53	levosimendan	levosimendan	PROPN
dti-2574	150	54	treatment	treatment	PROPN
dti-2574	150	55	,	,	PUNCT
dti-2574	150	56	rather	rather	ADV
dti-2574	150	57	than	than	ADP
dti-2574	150	58	inducing	induce	VERB
dti-2574	150	59	hypotension	hypotension	NOUN
dti-2574	150	60	,	,	PUNCT
dti-2574	150	61	maintained	maintain	VERB
dti-2574	150	62	higher	high	ADJ
dti-2574	150	63	levels	level	NOUN
dti-2574	150	64	of	of	ADP
dti-2574	150	65	map	map	NOUN
dti-2574	150	66	as	as	SCONJ
dti-2574	150	67	compared	compare	VERB
dti-2574	150	68	to	to	ADP
dti-2574	150	69	untreated	untreated	ADJ
dti-2574	150	70	animals	animal	NOUN
dti-2574	150	71	at	at	ADP
dti-2574	150	72	the	the	DET
dti-2574	150	73	end	end	NOUN
dti-2574	150	74	of	of	ADP
dti-2574	150	75	experiment	experiment	NOUN
dti-2574	150	76	(	(	PUNCT
dti-2574	150	77	tab	tab	NOUN
dti-2574	150	78	.	.	PUNCT
dti-2574	151	1	i	i	PRON
dti-2574	151	2	)	)	PUNCT
dti-2574	151	3	.	.	PUNCT
dti-2574	152	1	the	the	DET
dti-2574	152	2	diaphragmatic	diaphragmatic	ADJ
dti-2574	152	3	contraction	contraction	NOUN
dti-2574	152	4	was	be	AUX
dti-2574	152	5	evaluated	evaluate	VERB
dti-2574	152	6	by	by	ADP
dti-2574	152	7	in	in	ADP
dti-2574	152	8	vitro	vitro	X
dti-2574	152	9	electric	electric	ADJ
dti-2574	152	10	stimulation	stimulation	NOUN
dti-2574	152	11	after	after	ADP
dti-2574	152	12	5	5	NUM
dti-2574	152	13	hours	hour	NOUN
dti-2574	152	14	of	of	ADP
dti-2574	152	15	mv	mv	NOUN
dti-2574	152	16	:	:	PUNCT
dti-2574	152	17	both	both	DET
dti-2574	152	18	ventilated	ventilate	VERB
dti-2574	152	19	groups	group	NOUN
dti-2574	152	20	showed	show	VERB
dti-2574	152	21	a	a	DET
dti-2574	152	22	significant	significant	ADJ
dti-2574	152	23	reduction	reduction	NOUN
dti-2574	152	24	in	in	ADP
dti-2574	152	25	muscular	muscular	ADJ
dti-2574	152	26	force	force	NOUN
dti-2574	152	27	compared	compare	VERB
dti-2574	152	28	to	to	ADP
dti-2574	152	29	healthy	healthy	ADJ
dti-2574	152	30	control	control	NOUN
dti-2574	152	31	rats	rat	NOUN
dti-2574	152	32	(	(	PUNCT
dti-2574	152	33	fig	fig	NOUN
dti-2574	152	34	.	.	PUNCT
dti-2574	153	1	3a	3a	NUM
dti-2574	153	2	,	,	PUNCT
dti-2574	153	3	b	b	NOUN
dti-2574	153	4	)	)	PUNCT
dti-2574	153	5	.	.	PUNCT
dti-2574	154	1	levosimendan	levosimendan	PROPN
dti-2574	154	2	treatment	treatment	PROPN
dti-2574	154	3	did	do	AUX
dti-2574	154	4	not	not	PART
dti-2574	154	5	improve	improve	VERB
dti-2574	154	6	diaphragm	diaphragm	NOUN
dti-2574	154	7	contraction	contraction	NOUN
dti-2574	154	8	,	,	PUNCT
dti-2574	154	9	maybe	maybe	ADV
dti-2574	154	10	due	due	ADP
dti-2574	154	11	to	to	ADP
dti-2574	154	12	the	the	DET
dti-2574	154	13	bolus	bolus	ADJ
dti-2574	154	14	dose	dose	NOUN
dti-2574	154	15	used	use	VERB
dti-2574	154	16	in	in	ADP
dti-2574	154	17	the	the	DET
dti-2574	154	18	study	study	NOUN
dti-2574	154	19	:	:	PUNCT
dti-2574	154	20	24	24	NUM
dti-2574	154	21	vs.	vs.	CCONJ
dti-2574	154	22	40	40	NUM
dti-2574	154	23	µg	µg	NOUN
dti-2574	154	24	/	/	SYM
dti-2574	154	25	kg	kg	PROPN
dti-2574	154	26	,	,	PUNCT
dti-2574	154	27	which	which	PRON
dti-2574	154	28	was	be	AUX
dti-2574	154	29	used	use	VERB
dti-2574	154	30	in	in	ADP
dti-2574	154	31	similar	similar	ADJ
dti-2574	154	32	investigations	investigation	NOUN
dti-2574	154	33	(	(	PUNCT
dti-2574	154	34	27	27	NUM
dti-2574	154	35	)	)	PUNCT
dti-2574	154	36	.	.	PUNCT
dti-2574	155	1	however	however	ADV
dti-2574	155	2	,	,	PUNCT
dti-2574	155	3	histological	histological	ADJ
dti-2574	155	4	analysis	analysis	NOUN
dti-2574	155	5	of	of	ADP
dti-2574	155	6	muscular	muscular	ADJ
dti-2574	155	7	diaphragmatic	diaphragmatic	ADJ
dti-2574	155	8	fiber	fiber	NOUN
dti-2574	155	9	revealed	reveal	VERB
dti-2574	155	10	that	that	SCONJ
dti-2574	155	11	levosimendan	levosimendan	PROPN
dti-2574	155	12	administration	administration	PROPN
dti-2574	155	13	preserved	preserve	VERB
dti-2574	155	14	significant	significant	ADJ
dti-2574	155	15	cellular	cellular	ADJ
dti-2574	155	16	diameter	diameter	NOUN
dti-2574	155	17	from	from	ADP
dti-2574	155	18	atrophy	atrophy	NOUN
dti-2574	155	19	.	.	PUNCT
dti-2574	156	1	prolonged	prolong	VERB
dti-2574	156	2	mv	mv	PROPN
dti-2574	156	3	led	lead	VERB
dti-2574	156	4	to	to	ADP
dti-2574	156	5	a	a	DET
dti-2574	156	6	reduction	reduction	NOUN
dti-2574	156	7	in	in	ADP
dti-2574	156	8	cross	cross	ADJ
dti-2574	156	9	-	-	ADJ
dti-2574	156	10	sectional	sectional	ADJ
dti-2574	156	11	muscular	muscular	ADJ
dti-2574	156	12	fiber	fiber	NOUN
dti-2574	156	13	area	area	NOUN
dti-2574	156	14	of	of	ADP
dti-2574	156	15	16	16	NUM
dti-2574	156	16	%	%	NOUN
dti-2574	156	17	(	(	PUNCT
dti-2574	156	18	fig	fig	NOUN
dti-2574	156	19	.	.	PUNCT
dti-2574	157	1	1	1	NUM
dti-2574	157	2	)	)	PUNCT
dti-2574	157	3	,	,	PUNCT
dti-2574	157	4	whereas	whereas	SCONJ
dti-2574	157	5	levosimendan	levosimendan	ADJ
dti-2574	157	6	-	-	PUNCT
dti-2574	157	7	treated	treat	VERB
dti-2574	157	8	rats	rat	NOUN
dti-2574	157	9	showed	show	VERB
dti-2574	157	10	conserved	conserve	VERB
dti-2574	157	11	cellular	cellular	ADJ
dti-2574	157	12	structure	structure	NOUN
dti-2574	157	13	when	when	SCONJ
dti-2574	157	14	compared	compare	VERB
dti-2574	157	15	to	to	ADP
dti-2574	157	16	the	the	DET
dti-2574	157	17	vidd	vidd	NOUN
dti-2574	157	18	group	group	NOUN
dti-2574	157	19	.	.	PUNCT
dti-2574	158	1	the	the	DET
dti-2574	158	2	levels	level	NOUN
dti-2574	158	3	of	of	ADP
dti-2574	158	4	atrogin	atrogin	NOUN
dti-2574	158	5	,	,	PUNCT
dti-2574	158	6	a	a	DET
dti-2574	158	7	protein	protein	NOUN
dti-2574	158	8	belonging	belong	VERB
dti-2574	158	9	to	to	ADP
dti-2574	158	10	the	the	DET
dti-2574	158	11	ubiquitin	ubiquitin	ADJ
dti-2574	158	12	-	-	PUNCT
dti-2574	158	13	proteasome	proteasome	NOUN
dti-2574	158	14	system	system	NOUN
dti-2574	158	15	of	of	ADP
dti-2574	158	16	proteolysis	proteolysis	NOUN
dti-2574	158	17	,	,	PUNCT
dti-2574	158	18	did	do	AUX
dti-2574	158	19	not	not	PART
dti-2574	158	20	differ	differ	VERB
dti-2574	158	21	between	between	ADP
dti-2574	158	22	groups	group	NOUN
dti-2574	158	23	(	(	PUNCT
dti-2574	158	24	fig	fig	NOUN
dti-2574	158	25	.	.	PUNCT
dti-2574	159	1	2	2	NUM
dti-2574	159	2	)	)	PUNCT
dti-2574	159	3	,	,	PUNCT
dti-2574	159	4	whereas	whereas	SCONJ
dti-2574	159	5	microtubule	microtubule	NOUN
dti-2574	159	6	-	-	PUNCT
dti-2574	159	7	associated	associate	VERB
dti-2574	159	8	protein	protein	NOUN
dti-2574	159	9	light	light	NOUN
dti-2574	159	10	chain	chain	NOUN
dti-2574	159	11	3	3	NUM
dti-2574	160	1	i	i	NOUN
dti-2574	160	2	and	and	CCONJ
dti-2574	160	3	ii	ii	PROPN
dti-2574	160	4	(	(	PUNCT
dti-2574	160	5	lc3bi	lc3bi	PROPN
dti-2574	160	6	and	and	CCONJ
dti-2574	160	7	ii	ii	NOUN
dti-2574	160	8	)	)	PUNCT
dti-2574	160	9	,	,	PUNCT
dti-2574	160	10	autophagosome	autophagosome	VERB
dti-2574	160	11	marker	marker	NOUN
dti-2574	160	12	,	,	PUNCT
dti-2574	160	13	were	be	AUX
dti-2574	160	14	significantly	significantly	ADV
dti-2574	160	15	modified	modify	VERB
dti-2574	160	16	by	by	ADP
dti-2574	160	17	mv	mv	PROPN
dti-2574	160	18	.	.	PUNCT
dti-2574	161	1	it	it	PRON
dti-2574	161	2	has	have	AUX
dti-2574	161	3	been	be	AUX
dti-2574	161	4	previously	previously	ADV
dti-2574	161	5	reported	report	VERB
dti-2574	161	6	that	that	SCONJ
dti-2574	161	7	prolonged	prolong	VERB
dti-2574	161	8	mv	mv	PROPN
dti-2574	161	9	can	can	AUX
dti-2574	161	10	lead	lead	VERB
dti-2574	161	11	to	to	ADP
dti-2574	161	12	upregulation	upregulation	NOUN
dti-2574	161	13	of	of	ADP
dti-2574	161	14	atrogin	atrogin	NOUN
dti-2574	161	15	and	and	CCONJ
dti-2574	161	16	lc3b	lc3b	PROPN
dti-2574	161	17	(	(	PUNCT
dti-2574	161	18	4,31	4,31	NUM
dti-2574	161	19	)	)	PUNCT
dti-2574	161	20	.	.	PUNCT
dti-2574	162	1	we	we	PRON
dti-2574	162	2	hypothesize	hypothesize	VERB
dti-2574	162	3	that	that	SCONJ
dti-2574	162	4	,	,	PUNCT
dti-2574	162	5	in	in	ADP
dti-2574	162	6	our	our	PRON
dti-2574	162	7	experimental	experimental	ADJ
dti-2574	162	8	protocol	protocol	NOUN
dti-2574	162	9	,	,	PUNCT
dti-2574	162	10	the	the	DET
dti-2574	162	11	hours	hour	NOUN
dti-2574	162	12	of	of	ADP
dti-2574	162	13	mv	mv	PROPN
dti-2574	162	14	should	should	AUX
dti-2574	162	15	influence	influence	VERB
dti-2574	162	16	the	the	DET
dti-2574	162	17	protein	protein	NOUN
dti-2574	162	18	expression	expression	NOUN
dti-2574	162	19	,	,	PUNCT
dti-2574	162	20	maybe	maybe	ADV
dti-2574	162	21	5	5	NUM
dti-2574	162	22	hours	hour	NOUN
dti-2574	162	23	mv	mv	PROPN
dti-2574	162	24	were	be	AUX
dti-2574	162	25	not	not	PART
dti-2574	162	26	sufficient	sufficient	ADJ
dti-2574	162	27	to	to	PART
dti-2574	162	28	stimulate	stimulate	VERB
dti-2574	162	29	atrogin	atrogin	NOUN
dti-2574	162	30	production	production	NOUN
dti-2574	162	31	.	.	PUNCT
dti-2574	163	1	this	this	DET
dti-2574	163	2	study	study	NOUN
dti-2574	163	3	has	have	VERB
dti-2574	163	4	some	some	DET
dti-2574	163	5	limitations	limitation	NOUN
dti-2574	163	6	that	that	PRON
dti-2574	163	7	should	should	AUX
dti-2574	163	8	be	be	AUX
dti-2574	163	9	acknowledged	acknowledge	VERB
dti-2574	163	10	.	.	PUNCT
dti-2574	164	1	first	first	ADV
dti-2574	164	2	,	,	PUNCT
dti-2574	164	3	the	the	DET
dti-2574	164	4	duration	duration	NOUN
dti-2574	164	5	of	of	ADP
dti-2574	164	6	mv	mv	PROPN
dti-2574	164	7	(	(	PUNCT
dti-2574	164	8	5	5	NUM
dti-2574	164	9	hours	hour	NOUN
dti-2574	164	10	)	)	PUNCT
dti-2574	164	11	potentially	potentially	ADV
dti-2574	164	12	did	do	AUX
dti-2574	164	13	not	not	PART
dti-2574	164	14	allow	allow	VERB
dti-2574	164	15	enough	enough	ADJ
dti-2574	164	16	time	time	NOUN
dti-2574	164	17	to	to	PART
dti-2574	164	18	evaluate	evaluate	VERB
dti-2574	164	19	all	all	DET
dti-2574	164	20	the	the	DET
dti-2574	164	21	parameters	parameter	NOUN
dti-2574	164	22	(	(	PUNCT
dti-2574	164	23	such	such	ADJ
dti-2574	164	24	as	as	ADP
dti-2574	164	25	atrogin	atrogin	NOUN
dti-2574	164	26	levels	level	NOUN
dti-2574	164	27	)	)	PUNCT
dti-2574	164	28	.	.	PUNCT
dti-2574	165	1	however	however	ADV
dti-2574	165	2	,	,	PUNCT
dti-2574	165	3	the	the	DET
dti-2574	165	4	purpose	purpose	NOUN
dti-2574	165	5	of	of	ADP
dti-2574	165	6	this	this	DET
dti-2574	165	7	study	study	NOUN
dti-2574	165	8	was	be	AUX
dti-2574	165	9	to	to	PART
dti-2574	165	10	determine	determine	VERB
dti-2574	165	11	the	the	DET
dti-2574	165	12	early	early	ADJ
dti-2574	165	13	effects	effect	NOUN
dti-2574	165	14	of	of	ADP
dti-2574	165	15	levosimendan	levosimendan	PROPN
dti-2574	165	16	.	.	PUNCT
dti-2574	166	1	early	early	ADJ
dti-2574	166	2	administration	administration	NOUN
dti-2574	166	3	ensured	ensure	VERB
dti-2574	166	4	that	that	SCONJ
dti-2574	166	5	possible	possible	ADJ
dti-2574	166	6	side	side	NOUN
dti-2574	166	7	effects	effect	NOUN
dti-2574	166	8	on	on	ADP
dti-2574	166	9	hemodynamics	hemodynamic	NOUN
dti-2574	166	10	were	be	AUX
dti-2574	166	11	avoided	avoid	VERB
dti-2574	166	12	.	.	PUNCT
dti-2574	167	1	it	it	PRON
dti-2574	167	2	has	have	AUX
dti-2574	167	3	been	be	AUX
dti-2574	167	4	previously	previously	ADV
dti-2574	167	5	demonstrated	demonstrate	VERB
dti-2574	167	6	that	that	SCONJ
dti-2574	167	7	mv	mv	PROPN
dti-2574	167	8	can	can	AUX
dti-2574	167	9	have	have	VERB
dti-2574	167	10	detrimental	detrimental	ADJ
dti-2574	167	11	effects	effect	NOUN
dti-2574	167	12	on	on	ADP
dti-2574	167	13	muscle	muscle	NOUN
dti-2574	167	14	fibers	fiber	NOUN
dti-2574	167	15	.	.	PUNCT
dti-2574	168	1	therefore	therefore	ADV
dti-2574	168	2	,	,	PUNCT
dti-2574	168	3	future	future	ADJ
dti-2574	168	4	studies	study	NOUN
dti-2574	168	5	will	will	AUX
dti-2574	168	6	identify	identify	VERB
dti-2574	168	7	more	more	ADV
dti-2574	168	8	specifically	specifically	ADV
dti-2574	168	9	the	the	DET
dti-2574	168	10	different	different	ADJ
dti-2574	168	11	types	type	NOUN
dti-2574	168	12	of	of	ADP
dti-2574	168	13	muscle	muscle	NOUN
dti-2574	168	14	fibers	fiber	NOUN
dti-2574	168	15	after	after	ADP
dti-2574	168	16	mv	mv	PROPN
dti-2574	168	17	with	with	ADP
dti-2574	168	18	and	and	CCONJ
dti-2574	168	19	without	without	ADP
dti-2574	168	20	treatment	treatment	NOUN
dti-2574	168	21	.	.	PUNCT
dti-2574	169	1	second	second	ADJ
dti-2574	169	2	,	,	PUNCT
dti-2574	169	3	we	we	PRON
dti-2574	169	4	decided	decide	VERB
dti-2574	169	5	to	to	PART
dti-2574	169	6	administer	administer	VERB
dti-2574	169	7	the	the	DET
dti-2574	169	8	dose	dose	NOUN
dti-2574	169	9	of	of	ADP
dti-2574	169	10	levosimendan	levosimendan	PROPN
dti-2574	169	11	used	use	VERB
dti-2574	169	12	routinely	routinely	ADV
dti-2574	169	13	in	in	ADP
dti-2574	169	14	the	the	DET
dti-2574	169	15	clinical	clinical	ADJ
dti-2574	169	16	setting	setting	NOUN
dti-2574	169	17	(	(	PUNCT
dti-2574	169	18	decompensated	decompensate	VERB
dti-2574	169	19	heart	heart	NOUN
dti-2574	169	20	failure	failure	NOUN
dti-2574	169	21	)	)	PUNCT
dti-2574	169	22	.	.	PUNCT
dti-2574	170	1	we	we	PRON
dti-2574	170	2	can	can	AUX
dti-2574	170	3	not	not	PART
dti-2574	170	4	exclude	exclude	VERB
dti-2574	170	5	that	that	SCONJ
dti-2574	170	6	the	the	DET
dti-2574	170	7	use	use	NOUN
dti-2574	170	8	of	of	ADP
dti-2574	170	9	a	a	DET
dti-2574	170	10	higher	high	ADJ
dti-2574	170	11	dose	dose	NOUN
dti-2574	170	12	of	of	ADP
dti-2574	170	13	levosimendan	levosimendan	PROPN
dti-2574	170	14	might	might	AUX
dti-2574	170	15	provide	provide	VERB
dti-2574	170	16	a	a	DET
dti-2574	170	17	benefit	benefit	NOUN
dti-2574	170	18	in	in	ADP
dti-2574	170	19	terms	term	NOUN
dti-2574	170	20	of	of	ADP
dti-2574	170	21	diaphragmatic	diaphragmatic	ADJ
dti-2574	170	22	contraction	contraction	NOUN
dti-2574	170	23	.	.	PUNCT
dti-2574	171	1	a	a	DET
dti-2574	171	2	dose	dose	NOUN
dti-2574	171	3	-	-	PUNCT
dti-2574	171	4	response	response	NOUN
dti-2574	171	5	study	study	NOUN
dti-2574	171	6	may	may	AUX
dti-2574	171	7	be	be	AUX
dti-2574	171	8	a	a	DET
dti-2574	171	9	useful	useful	ADJ
dti-2574	171	10	potential	potential	ADJ
dti-2574	171	11	step	step	NOUN
dti-2574	171	12	to	to	PART
dti-2574	171	13	further	far	ADV
dti-2574	171	14	explore	explore	VERB
dti-2574	171	15	the	the	DET
dti-2574	171	16	role	role	NOUN
dti-2574	171	17	of	of	ADP
dti-2574	171	18	levosimendan	levosimendan	PROPN
dti-2574	171	19	during	during	ADP
dti-2574	171	20	vidd	vidd	NOUN
dti-2574	171	21	.	.	PUNCT
dti-2574	172	1	third	third	ADJ
dti-2574	172	2	,	,	PUNCT
dti-2574	172	3	during	during	ADP
dti-2574	172	4	the	the	DET
dti-2574	172	5	mv	mv	PROPN
dti-2574	172	6	period	period	NOUN
dti-2574	172	7	,	,	PUNCT
dti-2574	172	8	all	all	DET
dti-2574	172	9	rats	rat	NOUN
dti-2574	172	10	received	receive	VERB
dti-2574	172	11	a	a	DET
dti-2574	172	12	continuous	continuous	ADJ
dti-2574	172	13	infusion	infusion	NOUN
dti-2574	172	14	of	of	ADP
dti-2574	172	15	rocuronium	rocuronium	NOUN
dti-2574	172	16	bromide	bromide	NOUN
dti-2574	172	17	that	that	PRON
dti-2574	172	18	may	may	AUX
dti-2574	172	19	probably	probably	ADV
dti-2574	172	20	affect	affect	VERB
dti-2574	172	21	the	the	DET
dti-2574	172	22	diaphragmatic	diaphragmatic	ADJ
dti-2574	172	23	muscle	muscle	NOUN
dti-2574	172	24	contraction	contraction	NOUN
dti-2574	172	25	that	that	PRON
dti-2574	172	26	was	be	AUX
dti-2574	172	27	assessed	assess	VERB
dti-2574	172	28	ex	ex	PRON
dti-2574	172	29	vivo	vivo	NOUN
dti-2574	172	30	after	after	ADP
dti-2574	172	31	animal	animal	NOUN
dti-2574	172	32	euthanasia	euthanasia	NOUN
dti-2574	172	33	.	.	PUNCT
dti-2574	173	1	indeed	indeed	ADV
dti-2574	173	2	,	,	PUNCT
dti-2574	173	3	it	it	PRON
dti-2574	173	4	is	be	AUX
dti-2574	173	5	known	know	VERB
dti-2574	173	6	that	that	SCONJ
dti-2574	173	7	,	,	PUNCT
dti-2574	173	8	simultaneously	simultaneously	ADV
dti-2574	173	9	with	with	ADP
dti-2574	173	10	mv	mv	PROPN
dti-2574	173	11	,	,	PUNCT
dti-2574	173	12	some	some	DET
dti-2574	173	13	drugs	drug	NOUN
dti-2574	173	14	–	–	PUNCT
dti-2574	173	15	such	such	ADJ
dti-2574	173	16	as	as	ADP
dti-2574	173	17	neuromuscular	neuromuscular	ADJ
dti-2574	173	18	blocking	block	VERB
dti-2574	173	19	agents	agent	NOUN
dti-2574	173	20	–	–	PUNCT
dti-2574	173	21	may	may	AUX
dti-2574	173	22	worsen	worsen	VERB
dti-2574	173	23	the	the	DET
dti-2574	173	24	diaphragm	diaphragm	NOUN
dti-2574	173	25	dysfunction	dysfunction	NOUN
dti-2574	173	26	,	,	PUNCT
dti-2574	173	27	albeit	albeit	SCONJ
dti-2574	173	28	data	datum	NOUN
dti-2574	173	29	on	on	ADP
dti-2574	173	30	their	their	PRON
dti-2574	173	31	effects	effect	NOUN
dti-2574	173	32	on	on	ADP
dti-2574	173	33	diaphragm	diaphragm	NOUN
dti-2574	173	34	are	be	AUX
dti-2574	173	35	not	not	PART
dti-2574	173	36	debated	debate	VERB
dti-2574	173	37	(	(	PUNCT
dti-2574	173	38	32	32	NUM
dti-2574	173	39	-	-	SYM
dti-2574	173	40	35	35	NUM
dti-2574	173	41	)	)	PUNCT
dti-2574	173	42	.	.	PUNCT
dti-2574	174	1	in	in	ADP
dti-2574	174	2	conclusion	conclusion	NOUN
dti-2574	174	3	,	,	PUNCT
dti-2574	174	4	in	in	ADP
dti-2574	174	5	an	an	DET
dti-2574	174	6	experimental	experimental	ADJ
dti-2574	174	7	animal	animal	NOUN
dti-2574	174	8	model	model	NOUN
dti-2574	174	9	of	of	ADP
dti-2574	174	10	vidd	vidd	NOUN
dti-2574	174	11	,	,	PUNCT
dti-2574	174	12	levosimendan	levosimendan	PROPN
dti-2574	174	13	prevented	prevent	VERB
dti-2574	174	14	autophagy	autophagy	ADV
dti-2574	174	15	allowing	allow	VERB
dti-2574	174	16	to	to	PART
dti-2574	174	17	preserve	preserve	VERB
dti-2574	174	18	diaphragm	diaphragm	NOUN
dti-2574	174	19	muscular	muscular	ADJ
dti-2574	174	20	cellular	cellular	ADJ
dti-2574	174	21	structure	structure	NOUN
dti-2574	174	22	as	as	ADP
dti-2574	174	23	compared	compare	VERB
dti-2574	174	24	with	with	ADP
dti-2574	174	25	vidd	vidd	ADJ
dti-2574	174	26	untreated	untreated	ADJ
dti-2574	174	27	group	group	NOUN
dti-2574	174	28	.	.	PUNCT
dti-2574	175	1	however	however	ADV
dti-2574	175	2	,	,	PUNCT
dti-2574	175	3	levosimendan	levosimendan	PROPN
dti-2574	175	4	did	do	AUX
dti-2574	175	5	not	not	PART
dti-2574	175	6	improve	improve	VERB
dti-2574	175	7	the	the	DET
dti-2574	175	8	diaphragm	diaphragm	NOUN
dti-2574	175	9	contractile	contractile	NOUN
dti-2574	175	10	efficiency	efficiency	NOUN
dti-2574	175	11	.	.	PUNCT
dti-2574	176	1	disclosures	disclosure	VERB
dti-2574	176	2	conflict	conflict	NOUN
dti-2574	176	3	of	of	ADP
dti-2574	176	4	interest	interest	NOUN
dti-2574	176	5	:	:	PUNCT
dti-2574	176	6	the	the	DET
dti-2574	176	7	authors	author	NOUN
dti-2574	176	8	declare	declare	VERB
dti-2574	176	9	that	that	SCONJ
dti-2574	176	10	the	the	DET
dti-2574	176	11	research	research	NOUN
dti-2574	176	12	was	be	AUX
dti-2574	176	13	conducted	conduct	VERB
dti-2574	176	14	in	in	ADP
dti-2574	176	15	the	the	DET
dti-2574	176	16	absence	absence	NOUN
dti-2574	176	17	of	of	ADP
dti-2574	176	18	any	any	DET
dti-2574	176	19	commercial	commercial	ADJ
dti-2574	176	20	or	or	CCONJ
dti-2574	176	21	financial	financial	ADJ
dti-2574	176	22	relationships	relationship	NOUN
dti-2574	176	23	that	that	PRON
dti-2574	176	24	could	could	AUX
dti-2574	176	25	be	be	AUX
dti-2574	176	26	construed	construe	VERB
dti-2574	176	27	as	as	ADP
dti-2574	176	28	a	a	DET
dti-2574	176	29	potential	potential	ADJ
dti-2574	176	30	conflict	conflict	NOUN
dti-2574	176	31	of	of	ADP
dti-2574	176	32	interest	interest	NOUN
dti-2574	176	33	.	.	PUNCT
dti-2574	177	1	funding	funding	NOUN
dti-2574	177	2	/	/	SYM
dti-2574	177	3	support	support	NOUN
dti-2574	177	4	:	:	PUNCT
dti-2574	177	5	we	we	PRON
dti-2574	177	6	acknowledge	acknowledge	VERB
dti-2574	177	7	that	that	SCONJ
dti-2574	177	8	this	this	DET
dti-2574	177	9	research	research	NOUN
dti-2574	177	10	was	be	AUX
dti-2574	177	11	partially	partially	ADV
dti-2574	177	12	supported	support	VERB
dti-2574	177	13	by	by	ADP
dti-2574	177	14	the	the	DET
dti-2574	177	15	italian	italian	PROPN
dti-2574	177	16	ministry	ministry	PROPN
dti-2574	177	17	of	of	ADP
dti-2574	177	18	university	university	PROPN
dti-2574	177	19	and	and	CCONJ
dti-2574	177	20	research	research	NOUN
dti-2574	177	21	(	(	PUNCT
dti-2574	177	22	miur	miur	NOUN
dti-2574	177	23	)	)	PUNCT
dti-2574	177	24	,	,	PUNCT
dti-2574	177	25	department	department	NOUN
dti-2574	177	26	of	of	ADP
dti-2574	177	27	excellence	excellence	PROPN
dti-2574	177	28	project	project	PROPN
dti-2574	177	29	premia	premia	PROPN
dti-2574	177	30	(	(	PUNCT
dti-2574	177	31	precision	precision	NOUN
dti-2574	177	32	medicine	medicine	NOUN
dti-2574	177	33	approach	approach	NOUN
dti-2574	177	34	:	:	PUNCT
dti-2574	177	35	bringing	bring	VERB
dti-2574	177	36	biomarker	biomarker	NOUN
dti-2574	177	37	research	research	NOUN
dti-2574	177	38	to	to	ADP
dti-2574	177	39	clinic	clinic	NOUN
dti-2574	177	40	)	)	PUNCT
dti-2574	177	41	.	.	PUNCT
dti-2574	178	1	dr	dr	PROPN
dti-2574	178	2	.	.	PROPN
dti-2574	178	3	emanuele	emanuele	PROPN
dti-2574	178	4	rezoagli	rezoagli	PROPN
dti-2574	178	5	was	be	AUX
dti-2574	178	6	supported	support	VERB
dti-2574	178	7	by	by	ADP
dti-2574	178	8	the	the	DET
dti-2574	178	9	bicocca	bicocca	PROPN
dti-2574	178	10	starting	start	VERB
dti-2574	178	11	grant	grant	NOUN
dti-2574	178	12	2020	2020	NUM
dti-2574	178	13	from	from	ADP
dti-2574	178	14	the	the	DET
dti-2574	178	15	university	university	NOUN
dti-2574	178	16	of	of	ADP
dti-2574	178	17	milano	milano	PROPN
dti-2574	178	18	-	-	PUNCT
dti-2574	178	19	bicocca	bicocca	PROPN
dti-2574	178	20	with	with	ADP
dti-2574	178	21	the	the	DET
dti-2574	178	22	project	project	NOUN
dti-2574	178	23	titled	title	VERB
dti-2574	178	24	:	:	PUNCT
dti-2574	178	25	“	"	PUNCT
dti-2574	178	26	functional	functional	ADJ
dti-2574	178	27	residual	residual	ADJ
dti-2574	178	28	capacity	capacity	NOUN
dti-2574	178	29	assessment	assessment	NOUN
dti-2574	178	30	using	use	VERB
dti-2574	178	31	a	a	DET
dti-2574	178	32	wash	wash	NOUN
dti-2574	178	33	-	-	PUNCT
dti-2574	178	34	in	in	ADP
dti-2574	178	35	/	/	SYM
dti-2574	178	36	washout	washout	NOUN
dti-2574	178	37	technique	technique	NOUN
dti-2574	178	38	based	base	VERB
dti-2574	178	39	on	on	ADP
dti-2574	178	40	a	a	DET
dti-2574	178	41	fast	fast	ADJ
dti-2574	178	42	mainstream	mainstream	NOUN
dti-2574	178	43	o2	o2	ADJ
dti-2574	178	44	sensor	sensor	NOUN
dti-2574	178	45	with	with	ADP
dti-2574	178	46	nanofluorescent	nanofluorescent	NOUN
dti-2574	178	47	geometry	geometry	NOUN
dti-2574	178	48	for	for	ADP
dti-2574	178	49	severe	severe	ADJ
dti-2574	178	50	lung	lung	NOUN
dti-2574	178	51	injury	injury	NOUN
dti-2574	178	52	(	(	PUNCT
dti-2574	178	53	fast	fast	ADJ
dti-2574	178	54	)	)	PUNCT
dti-2574	178	55	–	–	PUNCT
dti-2574	178	56	covid	covid	PROPN
dti-2574	178	57	and	and	CCONJ
dti-2574	178	58	beyond	beyond	ADP
dti-2574	178	59	”	"	PUNCT
dti-2574	178	60	and	and	CCONJ
dti-2574	178	61	by	by	ADP
dti-2574	178	62	the	the	DET
dti-2574	178	63	international	international	ADJ
dti-2574	178	64	young	young	ADJ
dti-2574	178	65	investigator	investigator	NOUN
dti-2574	178	66	award	award	PROPN
dti-2574	178	67	2018	2018	NUM
dti-2574	178	68	from	from	ADP
dti-2574	178	69	the	the	DET
dti-2574	178	70	european	european	PROPN
dti-2574	178	71	society	society	NOUN
dti-2574	178	72	of	of	ADP
dti-2574	178	73	intensive	intensive	ADJ
dti-2574	178	74	care	care	NOUN
dti-2574	178	75	medicine	medicine	NOUN
dti-2574	178	76	(	(	PUNCT
dti-2574	178	77	esicm	esicm	NOUN
dti-2574	178	78	)	)	PUNCT
dti-2574	178	79	with	with	ADP
dti-2574	178	80	the	the	DET
dti-2574	178	81	project	project	NOUN
dti-2574	178	82	titled	title	VERB
dti-2574	178	83	:	:	PUNCT
dti-2574	178	84	“	"	PUNCT
dti-2574	178	85	role	role	NOUN
dti-2574	178	86	of	of	ADP
dti-2574	178	87	the	the	DET
dti-2574	178	88	exhaled	exhale	VERB
dti-2574	178	89	breath	breath	NOUN
dti-2574	178	90	condensate	condensate	NOUN
dti-2574	178	91	as	as	ADP
dti-2574	178	92	non	non	ADJ
dti-2574	178	93	-	-	ADJ
dti-2574	178	94	invasive	invasive	ADJ
dti-2574	178	95	monitoring	monitoring	NOUN
dti-2574	178	96	of	of	ADP
dti-2574	178	97	the	the	DET
dti-2574	178	98	lung	lung	NOUN
dti-2574	178	99	inflammation	inflammation	NOUN
dti-2574	178	100	during	during	ADP
dti-2574	178	101	ards	ard	NOUN
dti-2574	178	102	:	:	PUNCT
dti-2574	178	103	a	a	DET
dti-2574	178	104	prospective	prospective	ADJ
dti-2574	178	105	cohort	cohort	NOUN
dti-2574	178	106	study	study	NOUN
dti-2574	178	107	.	.	PUNCT
dti-2574	178	108	”	"	PUNCT
dti-2574	179	1	references	reference	NOUN
dti-2574	179	2	1	1	NUM
dti-2574	179	3	.	.	PUNCT
dti-2574	180	1	dreyfuss	dreyfuss	PROPN
dti-2574	180	2	d	d	PROPN
dti-2574	180	3	,	,	PUNCT
dti-2574	180	4	saumon	saumon	PROPN
dti-2574	180	5	g.	g.	PROPN
dti-2574	180	6	ventilator	ventilator	NOUN
dti-2574	180	7	-	-	PUNCT
dti-2574	180	8	induced	induce	VERB
dti-2574	180	9	lung	lung	NOUN
dti-2574	180	10	injury	injury	NOUN
dti-2574	180	11	:	:	PUNCT
dti-2574	180	12	lessons	lesson	NOUN
dti-2574	180	13	from	from	ADP
dti-2574	180	14	experimental	experimental	ADJ
dti-2574	180	15	studies	study	NOUN
dti-2574	180	16	.	.	PUNCT
dti-2574	181	1	am	be	AUX
dti-2574	181	2	j	j	PROPN
dti-2574	181	3	respir	respir	NOUN
dti-2574	181	4	crit	crit	PROPN
dti-2574	181	5	care	care	NOUN
dti-2574	181	6	med	me	VERB
dti-2574	181	7	.	.	PUNCT
dti-2574	182	1	1998;157(1):294	1998;157(1):294	NUM
dti-2574	182	2	-	-	SYM
dti-2574	182	3	323	323	NUM
dti-2574	182	4	.	.	PUNCT
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dti-2574	188	6	-	-	SYM
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dti-2574	188	10	.	.	PUNCT
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dti-2574	190	6	:	:	PUNCT
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dti-2574	190	10	.	.	PUNCT
dti-2574	191	1	intensive	intensive	ADJ
dti-2574	191	2	care	care	NOUN
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dti-2574	191	4	.	.	PUNCT
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dti-2574	192	2	-	-	SYM
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dti-2574	192	4	.	.	PUNCT
dti-2574	193	1	crossref	crossref	PROPN
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dti-2574	193	4	.	.	PUNCT
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dti-2574	195	8	.	.	PUNCT
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dti-2574	196	8	.	.	PUNCT
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dti-2574	200	6	.	.	PUNCT
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dti-2574	201	6	.	.	PUNCT
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dti-2574	201	12	.	.	PUNCT
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dti-2574	203	2	-	-	SYM
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dti-2574	203	4	.	.	PUNCT
dti-2574	204	1	crossref	crossref	PROPN
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dti-2574	204	4	.	.	PUNCT
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dti-2574	205	24	(	(	PUNCT
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dti-2574	207	4	:	:	PUNCT
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dti-2574	207	6	-	-	PUNCT
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dti-2574	207	8	-	-	PUNCT
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dti-2574	207	10	.	.	PUNCT
dti-2574	208	1	crossref	crossref	PROPN
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dti-2574	208	3	.	.	PUNCT
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dti-2574	209	5	.	.	PUNCT
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dti-2574	210	2	.	.	X
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dti-2574	210	5	,	,	PUNCT
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dti-2574	210	8	,	,	PUNCT
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dti-2574	210	25	in	in	ADP
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dti-2574	210	30	.	.	PUNCT
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dti-2574	211	2	.	.	PUNCT
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dti-2574	213	1	crossref	crossref	PROPN
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dti-2574	213	13	.	.	PUNCT
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dti-2574	218	3	,	,	PUNCT
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dti-2574	218	13	diaphragmatic	diaphragmatic	ADJ
dti-2574	218	14	structure	structure	NOUN
dti-2574	218	15	and	and	CCONJ
dti-2574	218	16	function	function	NOUN
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dti-2574	219	1	crit	crit	PROPN
dti-2574	219	2	care	care	PROPN
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dti-2574	219	4	.	.	PUNCT
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dti-2574	220	2	-	-	SYM
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dti-2574	220	5	crossref	crossref	PROPN
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dti-2574	220	8	.	.	PUNCT
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dti-2574	222	4	protein	protein	NOUN
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dti-2574	224	2	-	-	SYM
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dti-2574	227	4	.	.	PUNCT
dti-2574	228	1	2010;153(4):240	2010;153(4):240	NUM
dti-2574	228	2	-	-	SYM
dti-2574	228	3	245	245	NUM
dti-2574	228	4	.	.	PUNCT
dti-2574	229	1	crossref	crossref	PROPN
dti-2574	229	2	pubmed	pubmed	PROPN
dti-2574	229	3	13	13	PROPN
dti-2574	229	4	.	.	PUNCT
dti-2574	230	1	powers	power	NOUN
dti-2574	230	2	sk	sk	VERB
dti-2574	230	3	,	,	PUNCT
dti-2574	230	4	jackson	jackson	PROPN
dti-2574	230	5	mj	mj	PROPN
dti-2574	230	6	.	.	PROPN
dti-2574	230	7	exercise	exercise	NOUN
dti-2574	230	8	-	-	PUNCT
dti-2574	230	9	induced	induce	VERB
dti-2574	230	10	oxidative	oxidative	ADJ
dti-2574	230	11	stress	stress	NOUN
dti-2574	230	12	:	:	PUNCT
dti-2574	230	13	cellular	cellular	ADJ
dti-2574	230	14	mechanisms	mechanism	NOUN
dti-2574	230	15	and	and	CCONJ
dti-2574	230	16	impact	impact	NOUN
dti-2574	230	17	on	on	ADP
dti-2574	230	18	muscle	muscle	NOUN
dti-2574	230	19	force	force	NOUN
dti-2574	230	20	production	production	NOUN
dti-2574	230	21	.	.	PUNCT
dti-2574	231	1	physiol	physiol	PROPN
dti-2574	231	2	rev	rev	VERB
dti-2574	231	3	.	.	PUNCT
dti-2574	232	1	2008;88(4):1243	2008;88(4):1243	PROPN
dti-2574	232	2	-	-	PUNCT
dti-2574	232	3	1276	1276	NUM
dti-2574	232	4	.	.	PUNCT
dti-2574	233	1	crossref	crossref	PROPN
dti-2574	233	2	pubmed	pubmed	PROPN
dti-2574	233	3	14	14	PROPN
dti-2574	233	4	.	.	PUNCT
dti-2574	234	1	andrade	andrade	PROPN
dti-2574	234	2	fh	fh	PROPN
dti-2574	234	3	,	,	PUNCT
dti-2574	234	4	reid	reid	PROPN
dti-2574	234	5	mb	mb	PROPN
dti-2574	234	6	,	,	PUNCT
dti-2574	234	7	westerblad	westerblad	ADJ
dti-2574	234	8	h.	h.	NOUN
dti-2574	234	9	contractile	contractile	NOUN
dti-2574	234	10	response	response	NOUN
dti-2574	234	11	of	of	ADP
dti-2574	234	12	skeletal	skeletal	ADJ
dti-2574	234	13	muscle	muscle	NOUN
dti-2574	234	14	to	to	ADP
dti-2574	234	15	low	low	ADJ
dti-2574	234	16	peroxide	peroxide	NOUN
dti-2574	234	17	concentrations	concentration	NOUN
dti-2574	234	18	:	:	PUNCT
dti-2574	234	19	myofibrillar	myofibrillar	ADJ
dti-2574	234	20	calcium	calcium	NOUN
dti-2574	234	21	sensitivity	sensitivity	NOUN
dti-2574	234	22	as	as	ADP
dti-2574	234	23	a	a	DET
dti-2574	234	24	likely	likely	ADJ
dti-2574	234	25	target	target	NOUN
dti-2574	234	26	for	for	ADP
dti-2574	234	27	redox	redox	NOUN
dti-2574	234	28	-	-	PUNCT
dti-2574	234	29	modulation	modulation	NOUN
dti-2574	234	30	.	.	PUNCT
dti-2574	235	1	faseb	faseb	PROPN
dti-2574	235	2	j.	j.	PROPN
dti-2574	235	3	2001;15(2):309	2001;15(2):309	PROPN
dti-2574	235	4	-	-	PUNCT
dti-2574	235	5	311	311	NUM
dti-2574	235	6	.	.	PUNCT
dti-2574	236	1	crossref	crossref	PROPN
dti-2574	236	2	pubmed	pubmed	PROPN
dti-2574	236	3	15	15	PROPN
dti-2574	236	4	.	.	PUNCT
dti-2574	237	1	pollesello	pollesello	PROPN
dti-2574	237	2	p	p	PROPN
dti-2574	237	3	,	,	PUNCT
dti-2574	237	4	ovaska	ovaska	PROPN
dti-2574	237	5	m	m	PROPN
dti-2574	237	6	,	,	PUNCT
dti-2574	237	7	kaivola	kaivola	PROPN
dti-2574	237	8	j	j	PROPN
dti-2574	237	9	,	,	PUNCT
dti-2574	237	10	et	et	PROPN
dti-2574	237	11	al	al	PROPN
dti-2574	237	12	.	.	PUNCT
dti-2574	238	1	binding	bind	VERB
dti-2574	238	2	of	of	ADP
dti-2574	238	3	a	a	DET
dti-2574	238	4	new	new	ADJ
dti-2574	238	5	ca2	ca2	PROPN
dti-2574	238	6	+	+	NOUN
dti-2574	238	7	sensitizer	sensitizer	NOUN
dti-2574	238	8	,	,	PUNCT
dti-2574	238	9	levosimendan	levosimendan	PROPN
dti-2574	238	10	,	,	PUNCT
dti-2574	238	11	to	to	PART
dti-2574	238	12	recombinant	recombinant	VERB
dti-2574	238	13	human	human	ADJ
dti-2574	238	14	cardiac	cardiac	ADJ
dti-2574	238	15	troponin	troponin	PROPN
dti-2574	238	16	c.	c.	PROPN
dti-2574	238	17	a	a	DET
dti-2574	238	18	molecular	molecular	ADJ
dti-2574	238	19	modelling	modelling	NOUN
dti-2574	238	20	,	,	PUNCT
dti-2574	238	21	fluorescence	fluorescence	NOUN
dti-2574	238	22	probe	probe	NOUN
dti-2574	238	23	,	,	PUNCT
dti-2574	238	24	and	and	CCONJ
dti-2574	238	25	proton	proton	NOUN
dti-2574	238	26	nuclear	nuclear	ADJ
dti-2574	238	27	magnetic	magnetic	ADJ
dti-2574	238	28	resonance	resonance	NOUN
dti-2574	238	29	study	study	NOUN
dti-2574	238	30	.	.	PUNCT
dti-2574	239	1	j	j	PROPN
dti-2574	239	2	biol	biol	PROPN
dti-2574	239	3	chem	chem	NOUN
dti-2574	239	4	.	.	PUNCT
dti-2574	240	1	1994;269(46):28584	1994;269(46):28584	X
dti-2574	240	2	-	-	SYM
dti-2574	240	3	28590	28590	NUM
dti-2574	240	4	.	.	PUNCT
dti-2574	241	1	erratum	erratum	PROPN
dti-2574	241	2	in	in	ADP
dti-2574	241	3	:	:	PUNCT
dti-2574	241	4	j	j	PROPN
dti-2574	241	5	biol	biol	PROPN
dti-2574	241	6	chem	chem	NOUN
dti-2574	241	7	.	.	PUNCT
dti-2574	242	1	1995	1995	NUM
dti-2574	242	2	feb	feb	NOUN
dti-2574	242	3	10;270	10;270	NUM
dti-2574	242	4	.	.	PUNCT
dti-2574	243	1	6	6	NUM
dti-2574	243	2	.	.	PUNCT
dti-2574	243	3	:	:	PUNCT
dti-2574	244	1	2880	2880	NUM
dti-2574	244	2	.	.	PUNCT
dti-2574	245	1	crossref	crossref	PROPN
dti-2574	245	2	pubmed	pubmed	PROPN
dti-2574	245	3	16	16	NUM
dti-2574	245	4	.	.	PUNCT
dti-2574	246	1	haikala	haikala	PROPN
dti-2574	246	2	h	h	PROPN
dti-2574	246	3	,	,	PUNCT
dti-2574	246	4	kaivola	kaivola	PROPN
dti-2574	246	5	j	j	PROPN
dti-2574	246	6	,	,	PUNCT
dti-2574	246	7	nissinen	nissinen	PROPN
dti-2574	246	8	e	e	PROPN
dti-2574	246	9	,	,	PUNCT
dti-2574	246	10	wall	wall	PROPN
dti-2574	246	11	p	p	NOUN
dti-2574	246	12	,	,	PUNCT
dti-2574	246	13	levijoki	levijoki	PROPN
dti-2574	246	14	j	j	PROPN
dti-2574	246	15	,	,	PUNCT
dti-2574	246	16	lindén	lindén	PROPN
dti-2574	246	17	ib	ib	PROPN
dti-2574	246	18	.	.	PUNCT
dti-2574	247	1	cardiac	cardiac	ADJ
dti-2574	247	2	troponin	troponin	PROPN
dti-2574	247	3	c	c	PROPN
dti-2574	247	4	as	as	ADP
dti-2574	247	5	a	a	DET
dti-2574	247	6	target	target	NOUN
dti-2574	247	7	protein	protein	NOUN
dti-2574	247	8	for	for	ADP
dti-2574	247	9	a	a	DET
dti-2574	247	10	novel	novel	ADJ
dti-2574	247	11	calcium	calcium	NOUN
dti-2574	247	12	sensitizing	sensitize	VERB
dti-2574	247	13	drug	drug	NOUN
dti-2574	247	14	,	,	PUNCT
dti-2574	247	15	levosimendan	levosimendan	PROPN
dti-2574	247	16	.	.	PUNCT
dti-2574	248	1	j	j	PROPN
dti-2574	248	2	mol	mol	PROPN
dti-2574	248	3	cell	cell	NOUN
dti-2574	248	4	cardiol	cardiol	NOUN
dti-2574	248	5	.	.	PUNCT
dti-2574	249	1	1995;27(9):18591866	1995;27(9):18591866	PROPN
dti-2574	249	2	.	.	PUNCT
dti-2574	250	1	crossref	crossref	PROPN
dti-2574	250	2	pubmed	pubmed	PROPN
dti-2574	250	3	17	17	NUM
dti-2574	250	4	.	.	PUNCT
dti-2574	251	1	van	van	PROPN
dti-2574	251	2	hees	hees	PROPN
dti-2574	251	3	hw	hw	PROPN
dti-2574	251	4	,	,	PUNCT
dti-2574	251	5	dekhuijzen	dekhuijzen	PROPN
dti-2574	251	6	pn	pn	NOUN
dti-2574	251	7	,	,	PUNCT
dti-2574	251	8	heunks	heunk	VERB
dti-2574	251	9	lm	lm	INTJ
dti-2574	251	10	.	.	PUNCT
dti-2574	252	1	levosimendan	levosimendan	PROPN
dti-2574	252	2	enhances	enhance	VERB
dti-2574	252	3	force	force	NOUN
dti-2574	252	4	generation	generation	NOUN
dti-2574	252	5	of	of	ADP
dti-2574	252	6	diaphragm	diaphragm	NOUN
dti-2574	252	7	muscle	muscle	NOUN
dti-2574	252	8	from	from	ADP
dti-2574	252	9	patients	patient	NOUN
dti-2574	252	10	with	with	ADP
dti-2574	252	11	chronic	chronic	ADJ
dti-2574	252	12	obstructive	obstructive	ADJ
dti-2574	252	13	pulmonary	pulmonary	ADJ
dti-2574	252	14	disease	disease	NOUN
dti-2574	252	15	.	.	PUNCT
dti-2574	253	1	am	be	AUX
dti-2574	253	2	j	j	PROPN
dti-2574	253	3	respir	respir	NOUN
dti-2574	253	4	crit	crit	PROPN
dti-2574	253	5	care	care	NOUN
dti-2574	253	6	med	me	VERB
dti-2574	253	7	.	.	PUNCT
dti-2574	254	1	2009;179(1):41	2009;179(1):41	NUM
dti-2574	254	2	-	-	SYM
dti-2574	254	3	47	47	NUM
dti-2574	254	4	.	.	PUNCT
dti-2574	255	1	crossref	crossref	PROPN
dti-2574	255	2	pubmed	pubmed	PROPN
dti-2574	255	3	18	18	NUM
dti-2574	255	4	.	.	PUNCT
dti-2574	256	1	follath	follath	PROPN
dti-2574	256	2	f	f	PROPN
dti-2574	256	3	,	,	PUNCT
dti-2574	256	4	cleland	cleland	PROPN
dti-2574	256	5	jgf	jgf	PROPN
dti-2574	256	6	,	,	PUNCT
dti-2574	256	7	just	just	ADV
dti-2574	256	8	h	h	NOUN
dti-2574	256	9	,	,	PUNCT
dti-2574	256	10	et	et	PROPN
dti-2574	256	11	al	al	PROPN
dti-2574	256	12	;	;	PUNCT
dti-2574	256	13	steering	steering	NOUN
dti-2574	256	14	committee	committee	NOUN
dti-2574	256	15	and	and	CCONJ
dti-2574	256	16	investigators	investigator	NOUN
dti-2574	256	17	of	of	ADP
dti-2574	256	18	the	the	DET
dti-2574	256	19	levosimendan	levosimendan	PROPN
dti-2574	256	20	infusion	infusion	NOUN
dti-2574	256	21	versus	versus	ADP
dti-2574	256	22	dobutamine	dobutamine	ADJ
dti-2574	256	23	(	(	PUNCT
dti-2574	256	24	lido	lido	NOUN
dti-2574	256	25	)	)	PUNCT
dti-2574	256	26	study	study	NOUN
dti-2574	256	27	.	.	PUNCT
dti-2574	257	1	efficacy	efficacy	NOUN
dti-2574	257	2	and	and	CCONJ
dti-2574	257	3	safety	safety	NOUN
dti-2574	257	4	of	of	ADP
dti-2574	257	5	intravenous	intravenous	ADJ
dti-2574	257	6	levosimendan	levosimendan	NOUN
dti-2574	257	7	compared	compare	VERB
dti-2574	257	8	with	with	ADP
dti-2574	257	9	dobutamine	dobutamine	NOUN
dti-2574	257	10	in	in	ADP
dti-2574	257	11	severe	severe	ADJ
dti-2574	257	12	low	low	ADJ
dti-2574	257	13	-	-	PUNCT
dti-2574	257	14	output	output	NOUN
dti-2574	257	15	heart	heart	NOUN
dti-2574	257	16	failure	failure	NOUN
dti-2574	257	17	(	(	PUNCT
dti-2574	257	18	the	the	DET
dti-2574	257	19	lido	lido	NOUN
dti-2574	257	20	study	study	NOUN
dti-2574	257	21	):	):	PUNCT
dti-2574	257	22	a	a	DET
dti-2574	257	23	randomised	randomised	ADJ
dti-2574	257	24	double	double	ADJ
dti-2574	257	25	-	-	PUNCT
dti-2574	257	26	blind	blind	ADJ
dti-2574	257	27	trial	trial	NOUN
dti-2574	257	28	.	.	PUNCT
dti-2574	258	1	lancet	lancet	NOUN
dti-2574	258	2	.	.	PUNCT
dti-2574	259	1	2002;360(9328):196	2002;360(9328):196	NUM
dti-2574	259	2	-	-	SYM
dti-2574	259	3	202	202	NUM
dti-2574	259	4	.	.	PUNCT
dti-2574	260	1	crossref	crossref	PROPN
dti-2574	260	2	pubmed	pubmed	PROPN
dti-2574	260	3	19	19	NUM
dti-2574	260	4	.	.	PUNCT
dti-2574	261	1	sareila	sareila	PROPN
dti-2574	262	1	o	o	NOUN
dti-2574	262	2	,	,	PUNCT
dti-2574	262	3	korhonen	korhonen	PROPN
dti-2574	262	4	r	r	PROPN
dti-2574	262	5	,	,	PUNCT
dti-2574	262	6	auvinen	auvinen	PROPN
dti-2574	262	7	h	h	NOUN
dti-2574	262	8	,	,	PUNCT
dti-2574	262	9	et	et	PROPN
dti-2574	262	10	al	al	PROPN
dti-2574	262	11	.	.	PUNCT
dti-2574	262	12	effects	effect	NOUN
dti-2574	262	13	of	of	ADP
dti-2574	262	14	levoand	levoand	PROPN
dti-2574	262	15	dextrosimendan	dextrosimendan	PROPN
dti-2574	262	16	on	on	ADP
dti-2574	262	17	nf	nf	ADJ
dti-2574	262	18	-	-	PUNCT
dti-2574	262	19	kappab	kappab	NOUN
dti-2574	262	20	-	-	PUNCT
dti-2574	262	21	mediated	mediate	VERB
dti-2574	262	22	transcription	transcription	NOUN
dti-2574	262	23	,	,	PUNCT
dti-2574	262	24	inos	ino	NOUN
dti-2574	262	25	expression	expression	NOUN
dti-2574	262	26	and	and	CCONJ
dti-2574	262	27	no	no	DET
dti-2574	262	28	production	production	NOUN
dti-2574	262	29	in	in	ADP
dti-2574	262	30	response	response	NOUN
dti-2574	262	31	to	to	ADP
dti-2574	262	32	inflammatory	inflammatory	ADJ
dti-2574	262	33	stimuli	stimulus	NOUN
dti-2574	262	34	.	.	PUNCT
dti-2574	263	1	br	br	PROPN
dti-2574	263	2	j	j	PROPN
dti-2574	263	3	pharmacol	pharmacol	PROPN
dti-2574	263	4	.	.	PUNCT
dti-2574	264	1	2008;155(6):884	2008;155(6):884	NUM
dti-2574	264	2	-	-	SYM
dti-2574	264	3	895	895	NUM
dti-2574	264	4	.	.	PUNCT
dti-2574	265	1	crossref	crossref	PROPN
dti-2574	265	2	pubmed	pubmed	PROPN
dti-2574	265	3	20	20	NUM
dti-2574	265	4	.	.	PUNCT
dti-2574	266	1	schellekens	schelleken	NOUN
dti-2574	266	2	wj	wj	PROPN
dti-2574	266	3	,	,	PUNCT
dti-2574	266	4	van	van	PROPN
dti-2574	266	5	hees	hees	PROPN
dti-2574	266	6	hw	hw	PROPN
dti-2574	266	7	,	,	PUNCT
dti-2574	266	8	linkels	linkel	NOUN
dti-2574	266	9	m	m	PROPN
dti-2574	266	10	,	,	PUNCT
dti-2574	266	11	et	et	PROPN
dti-2574	266	12	al	al	PROPN
dti-2574	266	13	.	.	PROPN
dti-2574	266	14	levosimendan	levosimendan	PROPN
dti-2574	266	15	affects	affect	VERB
dti-2574	266	16	oxidative	oxidative	ADJ
dti-2574	266	17	and	and	CCONJ
dti-2574	266	18	inflammatory	inflammatory	ADJ
dti-2574	266	19	pathways	pathway	NOUN
dti-2574	266	20	in	in	ADP
dti-2574	266	21	the	the	DET
dti-2574	266	22	diaphragm	diaphragm	NOUN
dti-2574	266	23	of	of	ADP
dti-2574	266	24	ventilated	ventilate	VERB
dti-2574	266	25	endotoxemic	endotoxemic	ADJ
dti-2574	266	26	mice	mouse	NOUN
dti-2574	266	27	.	.	PUNCT
dti-2574	267	1	crit	crit	PROPN
dti-2574	267	2	care	care	NOUN
dti-2574	267	3	.	.	PUNCT
dti-2574	268	1	2015;19(1):69	2015;19(1):69	X
dti-2574	268	2	.	.	PUNCT
dti-2574	268	3	crossref	crossref	PROPN
dti-2574	268	4	pubmed	pubmed	PROPN
dti-2574	268	5	21	21	NUM
dti-2574	268	6	.	.	PUNCT
dti-2574	269	1	díaz	díaz	PROPN
dti-2574	269	2	l	l	PROPN
dti-2574	269	3	,	,	PUNCT
dti-2574	269	4	zambrano	zambrano	PROPN
dti-2574	269	5	e	e	PROPN
dti-2574	269	6	,	,	PUNCT
dti-2574	269	7	flores	flore	VERB
dti-2574	269	8	me	i	PRON
dti-2574	269	9	,	,	PUNCT
dti-2574	269	10	et	et	PROPN
dti-2574	269	11	al	al	PROPN
dti-2574	269	12	.	.	PUNCT
dti-2574	270	1	ethical	ethical	ADJ
dti-2574	270	2	considerations	consideration	NOUN
dti-2574	270	3	in	in	ADP
dti-2574	270	4	animal	animal	NOUN
dti-2574	270	5	research	research	NOUN
dti-2574	270	6	:	:	PUNCT
dti-2574	270	7	the	the	DET
dti-2574	270	8	principle	principle	NOUN
dti-2574	270	9	of	of	ADP
dti-2574	270	10	3r	3r	NUM
dti-2574	270	11	’s	’s	PART
dti-2574	270	12	.	.	PUNCT
dti-2574	271	1	rev	rev	AUX
dti-2574	271	2	invest	invest	VERB
dti-2574	271	3	clin	clin	PROPN
dti-2574	271	4	.	.	PUNCT
dti-2574	272	1	2020;73(4):199	2020;73(4):199	NUM
dti-2574	272	2	-	-	PUNCT
dti-2574	272	3	209	209	NUM
dti-2574	272	4	.	.	PUNCT
dti-2574	273	1	crossref	crossref	PROPN
dti-2574	273	2	pubmed	pubmed	PROPN
dti-2574	273	3	22	22	NUM
dti-2574	273	4	.	.	PUNCT
dti-2574	274	1	innes	innes	PROPN
dti-2574	274	2	ca	can	AUX
dti-2574	274	3	,	,	PUNCT
dti-2574	274	4	wagstaff	wagstaff	PROPN
dti-2574	274	5	aj	aj	PROPN
dti-2574	274	6	.	.	PROPN
dti-2574	275	1	levosimendan	levosimendan	PROPN
dti-2574	275	2	:	:	PUNCT
dti-2574	275	3	a	a	DET
dti-2574	275	4	review	review	NOUN
dti-2574	275	5	of	of	ADP
dti-2574	275	6	its	its	PRON
dti-2574	275	7	use	use	NOUN
dti-2574	275	8	in	in	ADP
dti-2574	275	9	the	the	DET
dti-2574	275	10	management	management	NOUN
dti-2574	275	11	of	of	ADP
dti-2574	275	12	acute	acute	ADJ
dti-2574	275	13	decompensated	decompensate	VERB
dti-2574	275	14	heart	heart	NOUN
dti-2574	275	15	failure	failure	NOUN
dti-2574	275	16	.	.	PUNCT
dti-2574	276	1	drugs	drug	NOUN
dti-2574	276	2	.	.	PUNCT
dti-2574	277	1	2003;63(23):2651	2003;63(23):2651	NUM
dti-2574	277	2	-	-	SYM
dti-2574	277	3	2671	2671	NUM
dti-2574	277	4	.	.	PUNCT
dti-2574	278	1	crossref	crossref	PROPN
dti-2574	278	2	pubmed	pubmed	PROPN
dti-2574	278	3	23	23	NUM
dti-2574	278	4	.	.	PUNCT
dti-2574	279	1	zambelli	zambelli	PROPN
dti-2574	279	2	v	v	PROPN
dti-2574	279	3	,	,	PUNCT
dti-2574	279	4	sigurtà	sigurtà	PROPN
dti-2574	279	5	a	a	X
dti-2574	279	6	,	,	PUNCT
dti-2574	279	7	rizzi	rizzi	PROPN
dti-2574	279	8	l	l	PROPN
dti-2574	279	9	,	,	PUNCT
dti-2574	279	10	et	et	PROPN
dti-2574	279	11	al	al	PROPN
dti-2574	279	12	.	.	PUNCT
dti-2574	280	1	angiotensin-(1	angiotensin-(1	PROPN
dti-2574	280	2	-	-	PUNCT
dti-2574	280	3	7	7	NUM
dti-2574	280	4	)	)	PUNCT
dti-2574	280	5	exerts	exert	VERB
dti-2574	280	6	a	a	DET
dti-2574	280	7	protective	protective	ADJ
dti-2574	280	8	action	action	NOUN
dti-2574	280	9	in	in	ADP
dti-2574	280	10	a	a	DET
dti-2574	280	11	rat	rat	NOUN
dti-2574	280	12	model	model	NOUN
dti-2574	280	13	of	of	ADP
dti-2574	280	14	ventilator	ventilator	NOUN
dti-2574	280	15	-	-	PUNCT
dti-2574	280	16	induced	induce	VERB
dti-2574	280	17	diaphragmatic	diaphragmatic	ADJ
dti-2574	280	18	dysfunction	dysfunction	NOUN
dti-2574	280	19	.	.	PUNCT
dti-2574	281	1	intensive	intensive	ADJ
dti-2574	281	2	care	care	NOUN
dti-2574	281	3	med	med	ADJ
dti-2574	281	4	exp	exp	NOUN
dti-2574	281	5	.	.	PUNCT
dti-2574	282	1	2019;7(1):8	2019;7(1):8	PROPN
dti-2574	282	2	.	.	PUNCT
dti-2574	283	1	crossref	crossref	PROPN
dti-2574	283	2	pubmed	pubmed	PROPN
dti-2574	283	3	24	24	NUM
dti-2574	283	4	.	.	PUNCT
dti-2574	284	1	papp	papp	PROPN
dti-2574	284	2	z	z	PROPN
dti-2574	284	3	,	,	PUNCT
dti-2574	284	4	agostoni	agostoni	NOUN
dti-2574	284	5	p	p	PROPN
dti-2574	284	6	,	,	PUNCT
dti-2574	284	7	alvarez	alvarez	PROPN
dti-2574	284	8	j	j	PROPN
dti-2574	284	9	,	,	PUNCT
dti-2574	284	10	et	et	PROPN
dti-2574	284	11	al	al	PROPN
dti-2574	284	12	.	.	PROPN
dti-2574	284	13	levosimendan	levosimendan	PROPN
dti-2574	284	14	efficacy	efficacy	PROPN
dti-2574	284	15	and	and	CCONJ
dti-2574	284	16	safety	safety	NOUN
dti-2574	284	17	:	:	PUNCT
dti-2574	284	18	20	20	NUM
dti-2574	284	19	years	year	NOUN
dti-2574	284	20	of	of	ADP
dti-2574	284	21	simdax	simdax	PROPN
dti-2574	284	22	in	in	ADP
dti-2574	284	23	clinical	clinical	ADJ
dti-2574	284	24	use	use	NOUN
dti-2574	284	25	.	.	PUNCT
dti-2574	285	1	j	j	PROPN
dti-2574	285	2	cardiovasc	cardiovasc	PROPN
dti-2574	285	3	pharmacol	pharmacol	PROPN
dti-2574	285	4	.	.	PUNCT
dti-2574	286	1	2020;76(1):4	2020;76(1):4	NUM
dti-2574	286	2	-	-	SYM
dti-2574	286	3	22	22	NUM
dti-2574	286	4	.	.	PUNCT
dti-2574	287	1	crossref	crossref	PROPN
dti-2574	287	2	pubmed	pubmed	PROPN
dti-2574	287	3	25	25	NUM
dti-2574	287	4	.	.	PUNCT
dti-2574	288	1	girardis	girardis	PROPN
dti-2574	288	2	m	m	PROPN
dti-2574	288	3	,	,	PUNCT
dti-2574	288	4	bettex	bettex	NOUN
dti-2574	288	5	d	d	PROPN
dti-2574	288	6	,	,	PUNCT
dti-2574	288	7	bojan	bojan	PROPN
dti-2574	288	8	m	m	PROPN
dti-2574	288	9	,	,	PUNCT
dti-2574	288	10	et	et	PROPN
dti-2574	288	11	al	al	PROPN
dti-2574	288	12	.	.	PROPN
dti-2574	288	13	levosimendan	levosimendan	PROPN
dti-2574	288	14	in	in	ADP
dti-2574	288	15	intensive	intensive	ADJ
dti-2574	288	16	care	care	NOUN
dti-2574	288	17	and	and	CCONJ
dti-2574	288	18	emergency	emergency	NOUN
dti-2574	288	19	medicine	medicine	NOUN
dti-2574	288	20	:	:	PUNCT
dti-2574	288	21	literature	literature	NOUN
dti-2574	288	22	update	update	NOUN
dti-2574	288	23	and	and	CCONJ
dti-2574	288	24	expert	expert	ADJ
dti-2574	288	25	recommendations	recommendation	NOUN
dti-2574	288	26	for	for	ADP
dti-2574	288	27	optimal	optimal	ADJ
dti-2574	288	28	efficacy	efficacy	NOUN
dti-2574	288	29	and	and	CCONJ
dti-2574	288	30	safety	safety	NOUN
dti-2574	288	31	.	.	PUNCT
dti-2574	289	1	j	j	PROPN
dti-2574	289	2	anesth	anesth	VERB
dti-2574	289	3	analg	analg	PROPN
dti-2574	289	4	crit	crit	PROPN
dti-2574	289	5	care	care	PROPN
dti-2574	289	6	.	.	PUNCT
dti-2574	290	1	2022;2(1):1	2022;2(1):1	PROPN
dti-2574	290	2	-	-	PUNCT
dti-2574	290	3	22	22	NUM
dti-2574	290	4	.	.	PUNCT
dti-2574	291	1	crossref	crossref	PROPN
dti-2574	291	2	26	26	NUM
dti-2574	291	3	.	.	PUNCT
dti-2574	292	1	hooijman	hooijman	NOUN
dti-2574	292	2	pe	pe	PROPN
dti-2574	292	3	,	,	PUNCT
dti-2574	292	4	beishuizen	beishuizen	VERB
dti-2574	292	5	a	a	PRON
dti-2574	292	6	,	,	PUNCT
dti-2574	292	7	de	de	X
dti-2574	292	8	waard	waard	PROPN
dti-2574	292	9	mc	mc	PROPN
dti-2574	292	10	,	,	PUNCT
dti-2574	292	11	et	et	PROPN
dti-2574	292	12	al	al	PROPN
dti-2574	292	13	.	.	PROPN
dti-2574	293	1	diaphragm	diaphragm	PROPN
dti-2574	293	2	fiber	fiber	NOUN
dti-2574	293	3	strength	strength	NOUN
dti-2574	293	4	is	be	AUX
dti-2574	293	5	reduced	reduce	VERB
dti-2574	293	6	in	in	ADP
dti-2574	293	7	critically	critically	ADV
dti-2574	293	8	ill	ill	ADJ
dti-2574	293	9	patients	patient	NOUN
dti-2574	293	10	and	and	CCONJ
dti-2574	293	11	restored	restore	VERB
dti-2574	293	12	by	by	ADP
dti-2574	293	13	a	a	DET
dti-2574	293	14	troponin	troponin	ADJ
dti-2574	293	15	activator	activator	NOUN
dti-2574	293	16	.	.	PUNCT
dti-2574	294	1	am	be	AUX
dti-2574	294	2	j	j	PROPN
dti-2574	294	3	respir	respir	NOUN
dti-2574	294	4	crit	crit	PROPN
dti-2574	294	5	care	care	NOUN
dti-2574	294	6	med	me	VERB
dti-2574	294	7	.	.	PUNCT
dti-2574	295	1	2014;189(7):863	2014;189(7):863	NUM
dti-2574	295	2	-	-	PUNCT
dti-2574	295	3	865	865	NUM
dti-2574	295	4	.	.	PUNCT
dti-2574	296	1	crossref	crossref	PROPN
dti-2574	296	2	pubmed	pubmed	PROPN
dti-2574	296	3	27	27	NUM
dti-2574	296	4	.	.	PUNCT
dti-2574	297	1	doorduin	doorduin	PROPN
dti-2574	297	2	j	j	PROPN
dti-2574	297	3	,	,	PUNCT
dti-2574	297	4	sinderby	sinderby	PROPN
dti-2574	297	5	ca	ca	PROPN
dti-2574	297	6	,	,	PUNCT
dti-2574	297	7	beck	beck	PROPN
dti-2574	297	8	j	j	PROPN
dti-2574	297	9	,	,	PUNCT
dti-2574	297	10	et	et	PROPN
dti-2574	297	11	al	al	PROPN
dti-2574	297	12	.	.	PUNCT
dti-2574	298	1	the	the	DET
dti-2574	298	2	calcium	calcium	NOUN
dti-2574	298	3	sensitizer	sensitizer	NOUN
dti-2574	298	4	levosimendan	levosimendan	NOUN
dti-2574	298	5	improves	improve	VERB
dti-2574	298	6	human	human	ADJ
dti-2574	298	7	diaphragm	diaphragm	NOUN
dti-2574	298	8	function	function	NOUN
dti-2574	298	9	.	.	PUNCT
dti-2574	299	1	am	be	AUX
dti-2574	299	2	j	j	PROPN
dti-2574	299	3	respir	respir	NOUN
dti-2574	299	4	crit	crit	PROPN
dti-2574	299	5	care	care	NOUN
dti-2574	299	6	med	me	VERB
dti-2574	299	7	.	.	PUNCT
dti-2574	300	1	2012;185(1):90	2012;185(1):90	NUM
dti-2574	300	2	-	-	SYM
dti-2574	300	3	95	95	NUM
dti-2574	300	4	.	.	PUNCT
dti-2574	301	1	crossref	crossref	PROPN
dti-2574	301	2	pubmed	pubmed	PROPN
dti-2574	301	3	28	28	PROPN
dti-2574	301	4	.	.	PUNCT
dti-2574	302	1	roesthuis	roesthuis	PROPN
dti-2574	302	2	l	l	PROPN
dti-2574	302	3	,	,	PUNCT
dti-2574	302	4	van	van	PROPN
dti-2574	302	5	der	der	PROPN
dti-2574	302	6	hoeven	hoeven	PROPN
dti-2574	302	7	h	h	PROPN
dti-2574	302	8	,	,	PUNCT
dti-2574	302	9	sinderby	sinderby	ADJ
dti-2574	302	10	c	c	NOUN
dti-2574	302	11	,	,	PUNCT
dti-2574	302	12	et	et	PROPN
dti-2574	302	13	al	al	PROPN
dti-2574	302	14	.	.	PUNCT
dti-2574	302	15	effects	effect	NOUN
dti-2574	302	16	of	of	ADP
dti-2574	302	17	levosimendan	levosimendan	PROPN
dti-2574	302	18	on	on	ADP
dti-2574	302	19	respiratory	respiratory	ADJ
dti-2574	302	20	muscle	muscle	NOUN
dti-2574	302	21	function	function	NOUN
dti-2574	302	22	in	in	ADP
dti-2574	302	23	patients	patient	NOUN
dti-2574	302	24	weaning	wean	VERB
dti-2574	302	25	from	from	ADP
dti-2574	302	26	mechanical	mechanical	ADJ
dti-2574	302	27	ventilation	ventilation	NOUN
dti-2574	302	28	.	.	PUNCT
dti-2574	303	1	intensive	intensive	ADJ
dti-2574	303	2	care	care	NOUN
dti-2574	303	3	med	me	VERB
dti-2574	303	4	.	.	PUNCT
dti-2574	304	1	2019;45(10):1372	2019;45(10):1372	NUM
dti-2574	304	2	-	-	SYM
dti-2574	304	3	1381	1381	NUM
dti-2574	304	4	.	.	PUNCT
dti-2574	305	1	crossref	crossref	PROPN
dti-2574	305	2	pubmed	pubmed	PROPN
dti-2574	305	3	29	29	NUM
dti-2574	305	4	.	.	PUNCT
dti-2574	306	1	zambelli	zambelli	PROPN
dti-2574	306	2	v	v	PROPN
dti-2574	306	3	,	,	PUNCT
dti-2574	306	4	rizzi	rizzi	PROPN
dti-2574	306	5	l	l	PROPN
dti-2574	306	6	,	,	PUNCT
dti-2574	306	7	delvecchio	delvecchio	VERB
dti-2574	306	8	p	p	PRON
dti-2574	306	9	,	,	PUNCT
dti-2574	306	10	et	et	PROPN
dti-2574	306	11	al	al	PROPN
dti-2574	306	12	.	.	PROPN
dti-2574	307	1	hexarelin	hexarelin	PROPN
dti-2574	307	2	modulates	modulate	VERB
dti-2574	307	3	lung	lung	NOUN
dti-2574	307	4	mechanics	mechanic	NOUN
dti-2574	307	5	,	,	PUNCT
dti-2574	307	6	inflammation	inflammation	NOUN
dti-2574	307	7	,	,	PUNCT
dti-2574	307	8	and	and	CCONJ
dti-2574	307	9	fibrosis	fibrosis	NOUN
dti-2574	307	10	in	in	ADP
dti-2574	307	11	acute	acute	ADJ
dti-2574	307	12	lung	lung	NOUN
dti-2574	307	13	injury	injury	NOUN
dti-2574	307	14	.	.	PUNCT
dti-2574	308	1	drug	drug	NOUN
dti-2574	308	2	target	target	NOUN
dti-2574	308	3	insights	insight	NOUN
dti-2574	308	4	.	.	PUNCT
dti-2574	309	1	2021;15:26	2021;15:26	NUM
dti-2574	309	2	-	-	SYM
dti-2574	309	3	33	33	NUM
dti-2574	309	4	.	.	PUNCT
dti-2574	310	1	crossref	crossref	PROPN
dti-2574	310	2	pubmed	pubmed	PROPN
dti-2574	310	3	30	30	PROPN
dti-2574	310	4	.	.	PUNCT
dti-2574	311	1	nieminen	nieminen	PROPN
dti-2574	311	2	ms	ms	PROPN
dti-2574	311	3	,	,	PUNCT
dti-2574	311	4	buerke	buerke	PROPN
dti-2574	311	5	m	m	PROPN
dti-2574	311	6	,	,	PUNCT
dti-2574	311	7	cohen	cohen	PROPN
dti-2574	311	8	-	-	PUNCT
dti-2574	311	9	solál	solál	PROPN
dti-2574	311	10	a	a	PRON
dti-2574	311	11	,	,	PUNCT
dti-2574	311	12	et	et	PROPN
dti-2574	311	13	al	al	PROPN
dti-2574	311	14	.	.	PUNCT
dti-2574	312	1	the	the	DET
dti-2574	312	2	role	role	NOUN
dti-2574	312	3	of	of	ADP
dti-2574	312	4	levosimendan	levosimendan	PROPN
dti-2574	312	5	in	in	ADP
dti-2574	312	6	acute	acute	ADJ
dti-2574	312	7	heart	heart	NOUN
dti-2574	312	8	failure	failure	NOUN
dti-2574	312	9	complicating	complicate	VERB
dti-2574	312	10	acute	acute	ADJ
dti-2574	312	11	coronary	coronary	ADJ
dti-2574	312	12	syndrome	syndrome	NOUN
dti-2574	312	13	:	:	PUNCT
dti-2574	312	14	a	a	DET
dti-2574	312	15	review	review	NOUN
dti-2574	312	16	and	and	CCONJ
dti-2574	312	17	expert	expert	ADJ
dti-2574	312	18	consensus	consensus	NOUN
dti-2574	312	19	opinion	opinion	NOUN
dti-2574	312	20	.	.	PUNCT
dti-2574	313	1	int	int	NOUN
dti-2574	313	2	j	j	PROPN
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dti-2574	313	4	.	.	PUNCT
dti-2574	314	1	2016;218:150	2016;218:150	NUM
dti-2574	314	2	-	-	SYM
dti-2574	314	3	157	157	NUM
dti-2574	314	4	.	.	PUNCT
dti-2574	315	1	crossref	crossref	PROPN
dti-2574	315	2	pubmed	pubmed	PROPN
dti-2574	315	3	31	31	NUM
dti-2574	315	4	.	.	PUNCT
dti-2574	316	1	schellekens	schelleken	NOUN
dti-2574	316	2	wj	wj	PROPN
dti-2574	316	3	,	,	PUNCT
dti-2574	316	4	van	van	PROPN
dti-2574	316	5	hees	hees	PROPN
dti-2574	316	6	hw	hw	PROPN
dti-2574	316	7	,	,	PUNCT
dti-2574	316	8	vaneker	vaneker	PROPN
dti-2574	316	9	m	m	PROPN
dti-2574	316	10	,	,	PUNCT
dti-2574	316	11	et	et	PROPN
dti-2574	316	12	al	al	PROPN
dti-2574	316	13	.	.	PUNCT
dti-2574	317	1	toll	toll	NOUN
dti-2574	317	2	-	-	PUNCT
dti-2574	317	3	like	like	ADJ
dti-2574	317	4	receptor	receptor	NOUN
dti-2574	317	5	4	4	NUM
dti-2574	317	6	signaling	signal	VERB
dti-2574	317	7	in	in	ADP
dti-2574	317	8	ventilator	ventilator	NOUN
dti-2574	317	9	-	-	PUNCT
dti-2574	317	10	induced	induce	VERB
dti-2574	317	11	diaphragm	diaphragm	NOUN
dti-2574	317	12	atrophy	atrophy	NOUN
dti-2574	317	13	.	.	PUNCT
dti-2574	318	1	anesthesiology	anesthesiology	NOUN
dti-2574	318	2	.	.	PUNCT
dti-2574	319	1	2012;117(2):329	2012;117(2):329	NUM
dti-2574	319	2	-	-	SYM
dti-2574	319	3	338	338	NUM
dti-2574	319	4	.	.	PUNCT
dti-2574	320	1	crossref	crossref	PROPN
dti-2574	320	2	pubmed	pubmed	PROPN
dti-2574	320	3	32	32	NUM
dti-2574	320	4	.	.	PUNCT
dti-2574	321	1	dres	dres	PROPN
dti-2574	321	2	m	m	PROPN
dti-2574	321	3	,	,	PUNCT
dti-2574	321	4	demoule	demoule	NOUN
dti-2574	321	5	a.	a.	NOUN
dti-2574	321	6	diaphragm	diaphragm	PROPN
dti-2574	321	7	dysfunction	dysfunction	NOUN
dti-2574	321	8	during	during	ADP
dti-2574	321	9	weaning	weaning	NOUN
dti-2574	321	10	from	from	ADP
dti-2574	321	11	mechanical	mechanical	ADJ
dti-2574	321	12	ventilation	ventilation	NOUN
dti-2574	321	13	:	:	PUNCT
dti-2574	321	14	an	an	DET
dti-2574	321	15	underestimated	underestimated	ADJ
dti-2574	321	16	phenomenon	phenomenon	NOUN
dti-2574	321	17	with	with	ADP
dti-2574	321	18	clinical	clinical	ADJ
dti-2574	321	19	implications	implication	NOUN
dti-2574	321	20	.	.	PUNCT
dti-2574	322	1	crit	crit	PROPN
dti-2574	322	2	care	care	NOUN
dti-2574	322	3	.	.	PUNCT
dti-2574	323	1	2018;22(1):73	2018;22(1):73	X
dti-2574	323	2	.	.	PUNCT
dti-2574	324	1	crossref	crossref	PROPN
dti-2574	324	2	pubmed	pubmed	PROPN
dti-2574	324	3	33	33	NUM
dti-2574	324	4	.	.	PUNCT
dti-2574	325	1	testelmans	testelmans	PROPN
dti-2574	325	2	d	d	PROPN
dti-2574	325	3	,	,	PUNCT
dti-2574	325	4	maes	maes	PROPN
dti-2574	325	5	k	k	PROPN
dti-2574	325	6	,	,	PUNCT
dti-2574	325	7	wouters	wouter	NOUN
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dti-2574	325	9	,	,	PUNCT
dti-2574	325	10	et	et	PROPN
dti-2574	325	11	al	al	PROPN
dti-2574	325	12	.	.	PROPN
dti-2574	325	13	rocuronium	rocuronium	NOUN
dti-2574	325	14	exacerbates	exacerbate	VERB
dti-2574	325	15	mechanical	mechanical	ADJ
dti-2574	325	16	ventilation	ventilation	NOUN
dti-2574	325	17	-	-	PUNCT
dti-2574	325	18	induced	induce	VERB
dti-2574	325	19	diaphragm	diaphragm	NOUN
dti-2574	325	20	dysfunction	dysfunction	NOUN
dti-2574	325	21	in	in	ADP
dti-2574	325	22	rats	rat	NOUN
dti-2574	325	23	.	.	PUNCT
dti-2574	326	1	crit	crit	PROPN
dti-2574	326	2	care	care	PROPN
dti-2574	326	3	med	me	VERB
dti-2574	326	4	.	.	PUNCT
dti-2574	327	1	2006;34(12):3018	2006;34(12):3018	NOUN
dti-2574	327	2	-	-	SYM
dti-2574	327	3	3023	3023	NUM
dti-2574	327	4	.	.	PUNCT
dti-2574	328	1	crossref	crossref	PROPN
dti-2574	328	2	pubmed	pubmed	PROPN
dti-2574	328	3	34	34	NUM
dti-2574	328	4	.	.	PUNCT
dti-2574	329	1	testelmans	testelmans	PROPN
dti-2574	329	2	d	d	PROPN
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dti-2574	329	5	k	k	PROPN
dti-2574	329	6	,	,	PUNCT
dti-2574	329	7	wouters	wouter	NOUN
dti-2574	329	8	p	p	X
dti-2574	329	9	,	,	PUNCT
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dti-2574	329	11	sk	sk	NOUN
dti-2574	329	12	,	,	PUNCT
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dti-2574	329	14	m	m	PROPN
dti-2574	329	15	,	,	PUNCT
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dti-2574	329	17	-	-	PUNCT
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dti-2574	329	19	g.	g.	PROPN
dti-2574	329	20	infusions	infusion	NOUN
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dti-2574	329	23	and	and	CCONJ
dti-2574	329	24	cisatracurium	cisatracurium	PROPN
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dti-2574	329	26	different	different	ADJ
dti-2574	329	27	effects	effect	NOUN
dti-2574	329	28	on	on	ADP
dti-2574	329	29	rat	rat	NOUN
dti-2574	329	30	diaphragm	diaphragm	NOUN
dti-2574	329	31	function	function	NOUN
dti-2574	329	32	.	.	PUNCT
dti-2574	330	1	intensive	intensive	ADJ
dti-2574	330	2	care	care	NOUN
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dti-2574	330	4	.	.	PUNCT
dti-2574	331	1	2007;33(5):872	2007;33(5):872	NUM
dti-2574	331	2	-	-	PUNCT
dti-2574	331	3	879	879	NUM
dti-2574	331	4	.	.	PUNCT
dti-2574	332	1	crossref	crossref	PROPN
dti-2574	332	2	pubmed	pubmed	PROPN
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dti-2574	332	4	.	.	PUNCT
dti-2574	333	1	hraiech	hraiech	PROPN
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dti-2574	333	8	l.	l.	PROPN
dti-2574	334	1	the	the	DET
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dti-2574	334	5	blockers	blocker	NOUN
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dti-2574	334	8	:	:	PUNCT
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dti-2574	334	10	and	and	CCONJ
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dti-2574	335	1	curr	curr	PROPN
dti-2574	335	2	opin	opin	PROPN
dti-2574	335	3	crit	crit	NOUN
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dti-2574	335	5	.	.	PUNCT
dti-2574	336	1	2012;18(5):495	2012;18(5):495	NUM
dti-2574	336	2	-	-	PUNCT
dti-2574	336	3	502	502	NUM
dti-2574	336	4	.	.	PUNCT
dti-2574	337	1	crossref	crossref	PROPN
dti-2574	337	2	pubmed	pubmed	PROPN
dti-2574	337	3	https://doi.org/10.1007/s00134-020-06141-z	https://doi.org/10.1007/s00134-020-06141-z	PROPN
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dti-2574	337	5	https://doi.org/10.1152/ajpregu.00231.2013	https://doi.org/10.1152/ajpregu.00231.2013	PROPN
dti-2574	337	6	https://www.ncbi.nlm.nih.gov/pubmed/23842681	https://www.ncbi.nlm.nih.gov/pubmed/23842681	PRON
dti-2574	337	7	https://doi.org/10.3390/diagnostics12112890	https://doi.org/10.3390/diagnostics12112890	VERB
dti-2574	337	8	https://www.ncbi.nlm.nih.gov/pubmed/36428947	https://www.ncbi.nlm.nih.gov/pubmed/36428947	NUM
dti-2574	337	9	https://doi.org/10.1164/rccm.200304-489cp	https://doi.org/10.1164/rccm.200304-489cp	X
dti-2574	337	10	https://www.ncbi.nlm.nih.gov/pubmed/14739134	https://www.ncbi.nlm.nih.gov/pubmed/14739134	X
dti-2574	338	1	https://doi.org/10.1016/s2213-2600(22)00449-0	https://doi.org/10.1016/s2213-2600(22)00449-0	PROPN
dti-2574	338	2	https://www.ncbi.nlm.nih.gov/pubmed/36693401	https://www.ncbi.nlm.nih.gov/pubmed/36693401	NUM
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dti-2574	338	4	https://www.ncbi.nlm.nih.gov/pubmed/35700589	https://www.ncbi.nlm.nih.gov/pubmed/35700589	NOUN
dti-2574	339	1	https://doi.org/10.1016/s0022-3476(88)80585-7	https://doi.org/10.1016/s0022-3476(88)80585-7	PROPN
dti-2574	339	2	https://www.ncbi.nlm.nih.gov/pubmed/3142983	https://www.ncbi.nlm.nih.gov/pubmed/3142983	NUM
dti-2574	340	1	https://doi.org/10.1097/ccm.0b013e3181b6e760	https://doi.org/10.1097/ccm.0b013e3181b6e760	PRON
dti-2574	340	2	https://www.ncbi.nlm.nih.gov/pubmed/20046120	https://www.ncbi.nlm.nih.gov/pubmed/20046120	PRON
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dti-2574	340	4	https://www.ncbi.nlm.nih.gov/pubmed/15297271	https://www.ncbi.nlm.nih.gov/pubmed/15297271	NOUN
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dti-2574	340	6	https://www.ncbi.nlm.nih.gov/pubmed/20713792	https://www.ncbi.nlm.nih.gov/pubmed/20713792	NUM
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dti-2574	341	1	https://www.ncbi.nlm.nih.gov/pubmed/11156946	https://www.ncbi.nlm.nih.gov/pubmed/11156946	NUM
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dti-2574	341	7	https://www.ncbi.nlm.nih.gov/pubmed/18990676	https://www.ncbi.nlm.nih.gov/pubmed/18990676	NUM
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dti-2574	341	10	https://doi.org/10.1038/bjp.2008.328	https://doi.org/10.1038/bjp.2008.328	PROPN
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dti-2574	341	12	https://doi.org/10.1186/s13054-015-0798-8	https://doi.org/10.1186/s13054-015-0798-8	NUM
dti-2574	341	13	https://www.ncbi.nlm.nih.gov/pubmed/25888356	https://www.ncbi.nlm.nih.gov/pubmed/25888356	NUM
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dti-2574	341	40	https://www.ncbi.nlm.nih.gov/pubmed/17361387	https://www.ncbi.nlm.nih.gov/pubmed/17361387	NUM
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