id	sid	tid	token	lemma	pos
dti-2638	1	1	dti	dti	PROPN
dti-2638	1	2	drug	drug	PROPN
dti-2638	1	3	target	target	NOUN
dti-2638	1	4	insights	insight	NOUN
dti-2638	1	5	2023	2023	NUM
dti-2638	1	6	;	;	PUNCT
dti-2638	1	7	17	17	NUM
dti-2638	1	8	:	:	SYM
dti-2638	1	9	101	101	NUM
dti-2638	1	10	-	-	SYM
dti-2638	1	11	109	109	NUM
dti-2638	1	12	issn	issn	PROPN
dti-2638	1	13	1177	1177	NUM
dti-2638	1	14	-	-	SYM
dti-2638	1	15	3928	3928	NUM
dti-2638	1	16	|	|	ADV
dti-2638	1	17	doi	doi	NOUN
dti-2638	1	18	:	:	PUNCT
dti-2638	1	19	10.33393	10.33393	NUM
dti-2638	1	20	/	/	SYM
dti-2638	1	21	dti.2023.2638	dti.2023.2638	ADJ
dti-2638	1	22	original	original	ADJ
dti-2638	1	23	research	research	NOUN
dti-2638	1	24	article	article	NOUN
dti-2638	1	25	drug	drug	NOUN
dti-2638	1	26	target	target	NOUN
dti-2638	1	27	insights	insight	NOUN
dti-2638	1	28	issn	issn	VERB
dti-2638	1	29	1177	1177	NUM
dti-2638	1	30	-	-	SYM
dti-2638	1	31	3928	3928	NUM
dti-2638	1	32	www.aboutscience.eu/dti	www.aboutscience.eu/dti	NOUN
dti-2638	1	33	©	©	PROPN
dti-2638	1	34	2023	2023	NUM
dti-2638	1	35	the	the	DET
dti-2638	1	36	authors	author	NOUN
dti-2638	1	37	.	.	PUNCT
dti-2638	2	1	this	this	DET
dti-2638	2	2	article	article	NOUN
dti-2638	2	3	is	be	AUX
dti-2638	2	4	published	publish	VERB
dti-2638	2	5	by	by	ADP
dti-2638	2	6	aboutscience	aboutscience	NOUN
dti-2638	2	7	and	and	CCONJ
dti-2638	2	8	licensed	license	VERB
dti-2638	2	9	under	under	ADP
dti-2638	2	10	creative	creative	ADJ
dti-2638	2	11	commons	common	NOUN
dti-2638	2	12	attribution	attribution	NOUN
dti-2638	2	13	-	-	PUNCT
dti-2638	2	14	noncommercial	noncommercial	ADJ
dti-2638	2	15	4.0	4.0	NUM
dti-2638	2	16	international	international	NOUN
dti-2638	2	17	(	(	PUNCT
dti-2638	2	18	cc	cc	NOUN
dti-2638	2	19	by	by	ADP
dti-2638	2	20	-	-	PUNCT
dti-2638	2	21	nc	nc	PROPN
dti-2638	2	22	4.0	4.0	NUM
dti-2638	2	23	)	)	PUNCT
dti-2638	2	24	.	.	PUNCT
dti-2638	3	1	commercial	commercial	ADJ
dti-2638	3	2	use	use	NOUN
dti-2638	3	3	is	be	AUX
dti-2638	3	4	not	not	PART
dti-2638	3	5	permitted	permit	VERB
dti-2638	3	6	and	and	CCONJ
dti-2638	3	7	is	be	AUX
dti-2638	3	8	subject	subject	ADJ
dti-2638	3	9	to	to	ADP
dti-2638	3	10	publisher	publisher	NOUN
dti-2638	3	11	’s	’s	PART
dti-2638	3	12	permissions	permission	NOUN
dti-2638	3	13	.	.	PUNCT
dti-2638	4	1	full	full	ADJ
dti-2638	4	2	information	information	NOUN
dti-2638	4	3	is	be	AUX
dti-2638	4	4	available	available	ADJ
dti-2638	4	5	at	at	ADP
dti-2638	4	6	www.aboutscience.eu	www.aboutscience.eu	NOUN
dti-2638	4	7	identification	identification	NOUN
dti-2638	4	8	of	of	ADP
dti-2638	4	9	anti	anti	ADJ
dti-2638	4	10	-	-	ADJ
dti-2638	4	11	pathogenic	pathogenic	ADJ
dti-2638	4	12	activity	activity	NOUN
dti-2638	4	13	among	among	ADP
dti-2638	4	14	in	in	ADP
dti-2638	4	15	silico	silico	NOUN
dti-2638	4	16	predicted	predict	VERB
dti-2638	4	17	small	small	ADJ
dti-2638	4	18	-	-	PUNCT
dti-2638	4	19	molecule	molecule	NOUN
dti-2638	4	20	inhibitors	inhibitor	NOUN
dti-2638	4	21	of	of	ADP
dti-2638	4	22	pseudomonas	pseudomona	NOUN
dti-2638	4	23	aeruginosa	aeruginosa	NOUN
dti-2638	4	24	lasr	lasr	PROPN
dti-2638	4	25	or	or	CCONJ
dti-2638	4	26	nitric	nitric	ADJ
dti-2638	4	27	oxide	oxide	NOUN
dti-2638	4	28	reductase	reductase	NOUN
dti-2638	4	29	(	(	PUNCT
dti-2638	4	30	nor	nor	CCONJ
dti-2638	4	31	)	)	PUNCT
dti-2638	4	32	gemini	gemini	NOUN
dti-2638	4	33	gajera1	gajera1	PROPN
dti-2638	4	34	,	,	PUNCT
dti-2638	4	35	niel	niel	PROPN
dti-2638	4	36	henriksen2	henriksen2	PROPN
dti-2638	4	37	,	,	PUNCT
dti-2638	4	38	bryan	bryan	PROPN
dti-2638	4	39	cox2	cox2	PROPN
dti-2638	4	40	,	,	PUNCT
dti-2638	5	1	vijay	vijay	NOUN
dti-2638	5	2	kothari1	kothari1	NOUN
dti-2638	6	1	1institute	1institute	NUM
dti-2638	6	2	of	of	ADP
dti-2638	6	3	science	science	NOUN
dti-2638	6	4	,	,	PUNCT
dti-2638	6	5	nirma	nirma	VERB
dti-2638	6	6	university	university	PROPN
dti-2638	6	7	,	,	PUNCT
dti-2638	6	8	ahmedabad	ahmedabad	PROPN
dti-2638	6	9	india	india	PROPN
dti-2638	6	10	2atomwise	2atomwise	NUM
dti-2638	6	11	inc	inc	PROPN
dti-2638	6	12	,	,	PUNCT
dti-2638	6	13	san	san	PROPN
dti-2638	6	14	francisco	francisco	PROPN
dti-2638	6	15	,	,	PUNCT
dti-2638	6	16	ca	ca	PROPN
dti-2638	6	17	usa	usa	PROPN
dti-2638	6	18	abstract	abstract	ADJ
dti-2638	6	19	introduction	introduction	NOUN
dti-2638	6	20	:	:	PUNCT
dti-2638	6	21	antibiotic	antibiotic	ADJ
dti-2638	6	22	-	-	PUNCT
dti-2638	6	23	resistant	resistant	ADJ
dti-2638	6	24	pseudomonas	pseudomona	NOUN
dti-2638	6	25	aeruginosa	aeruginosa	NOUN
dti-2638	6	26	strains	strain	NOUN
dti-2638	6	27	cause	cause	VERB
dti-2638	6	28	considerable	considerable	ADJ
dti-2638	6	29	morbidity	morbidity	NOUN
dti-2638	6	30	and	and	CCONJ
dti-2638	6	31	mortality	mortality	NOUN
dti-2638	6	32	globally	globally	ADV
dti-2638	6	33	.	.	PUNCT
dti-2638	7	1	identification	identification	NOUN
dti-2638	7	2	of	of	ADP
dti-2638	7	3	novel	novel	ADJ
dti-2638	7	4	targets	target	NOUN
dti-2638	7	5	in	in	ADP
dti-2638	7	6	this	this	DET
dti-2638	7	7	notorious	notorious	ADJ
dti-2638	7	8	pathogen	pathogen	NOUN
dti-2638	7	9	is	be	AUX
dti-2638	7	10	urgently	urgently	ADV
dti-2638	7	11	warranted	warrant	VERB
dti-2638	7	12	to	to	PART
dti-2638	7	13	facilitate	facilitate	VERB
dti-2638	7	14	discovery	discovery	NOUN
dti-2638	7	15	of	of	ADP
dti-2638	7	16	new	new	ADJ
dti-2638	7	17	anti	anti	ADJ
dti-2638	7	18	-	-	ADJ
dti-2638	7	19	pathogenic	pathogenic	ADJ
dti-2638	7	20	agents	agent	NOUN
dti-2638	7	21	against	against	ADP
dti-2638	7	22	it	it	PRON
dti-2638	7	23	.	.	PUNCT
dti-2638	8	1	this	this	DET
dti-2638	8	2	study	study	NOUN
dti-2638	8	3	attempted	attempt	VERB
dti-2638	8	4	to	to	PART
dti-2638	8	5	identify	identify	VERB
dti-2638	8	6	small	small	ADJ
dti-2638	8	7	-	-	PUNCT
dti-2638	8	8	molecule	molecule	NOUN
dti-2638	8	9	inhibitors	inhibitor	NOUN
dti-2638	8	10	of	of	ADP
dti-2638	8	11	two	two	NUM
dti-2638	8	12	important	important	ADJ
dti-2638	8	13	proteins	protein	NOUN
dti-2638	8	14	lasr	lasr	NOUN
dti-2638	8	15	and	and	CCONJ
dti-2638	8	16	nitric	nitric	ADJ
dti-2638	8	17	oxide	oxide	NOUN
dti-2638	8	18	reductase	reductase	NOUN
dti-2638	8	19	(	(	PUNCT
dti-2638	8	20	nor	nor	CCONJ
dti-2638	8	21	)	)	PUNCT
dti-2638	8	22	in	in	ADP
dti-2638	8	23	p.	p.	PROPN
dti-2638	8	24	aeruginosa	aeruginosa	PROPN
dti-2638	8	25	.	.	PUNCT
dti-2638	9	1	‘	'	PUNCT
dti-2638	9	2	las	las	NOUN
dti-2638	9	3	’	'	PUNCT
dti-2638	9	4	system	system	NOUN
dti-2638	9	5	can	can	AUX
dti-2638	9	6	be	be	AUX
dti-2638	9	7	said	say	VERB
dti-2638	9	8	to	to	PART
dti-2638	9	9	be	be	AUX
dti-2638	9	10	the	the	DET
dti-2638	9	11	‘	'	PUNCT
dti-2638	9	12	master	master	NOUN
dti-2638	9	13	’	'	PUNCT
dti-2638	9	14	regulator	regulator	NOUN
dti-2638	9	15	of	of	ADP
dti-2638	9	16	quorum	quorum	NOUN
dti-2638	9	17	sensing	sense	VERB
dti-2638	9	18	in	in	ADP
dti-2638	9	19	p.	p.	PROPN
dti-2638	9	20	aeruginosa	aeruginosa	PROPN
dti-2638	9	21	,	,	PUNCT
dti-2638	9	22	whose	whose	DET
dti-2638	9	23	receptor	receptor	NOUN
dti-2638	9	24	protein	protein	NOUN
dti-2638	9	25	is	be	AUX
dti-2638	9	26	lasr	lasr	PROPN
dti-2638	9	27	.	.	PUNCT
dti-2638	10	1	similarly	similarly	ADV
dti-2638	10	2	,	,	PUNCT
dti-2638	10	3	nor	nor	CCONJ
dti-2638	10	4	is	be	AUX
dti-2638	10	5	crucial	crucial	ADJ
dti-2638	10	6	to	to	ADP
dti-2638	10	7	detoxification	detoxification	VERB
dti-2638	10	8	of	of	ADP
dti-2638	10	9	reactive	reactive	ADJ
dti-2638	10	10	nitrogen	nitrogen	NOUN
dti-2638	10	11	species	specie	NOUN
dti-2638	10	12	.	.	PUNCT
dti-2638	11	1	methods	method	NOUN
dti-2638	11	2	:	:	PUNCT
dti-2638	11	3	in	in	ADP
dti-2638	11	4	silico	silico	NOUN
dti-2638	11	5	identification	identification	NOUN
dti-2638	11	6	of	of	ADP
dti-2638	11	7	potential	potential	ADJ
dti-2638	11	8	lasr	lasr	PROPN
dti-2638	11	9	or	or	CCONJ
dti-2638	11	10	nor	nor	CCONJ
dti-2638	11	11	inhibitors	inhibitor	NOUN
dti-2638	11	12	was	be	AUX
dti-2638	11	13	attempted	attempt	VERB
dti-2638	11	14	through	through	ADP
dti-2638	11	15	a	a	DET
dti-2638	11	16	virtual	virtual	ADJ
dti-2638	11	17	screening	screening	NOUN
dti-2638	11	18	platform	platform	NOUN
dti-2638	11	19	atomnet	atomnet	NOUN
dti-2638	11	20	®	®	NOUN
dti-2638	11	21	to	to	PART
dti-2638	11	22	obtain	obtain	VERB
dti-2638	11	23	a	a	DET
dti-2638	11	24	final	final	ADJ
dti-2638	11	25	subset	subset	NOUN
dti-2638	11	26	of	of	ADP
dti-2638	11	27	<	<	NOUN
dti-2638	11	28	100	100	NUM
dti-2638	11	29	top	top	ADJ
dti-2638	11	30	scoring	scoring	NOUN
dti-2638	11	31	compounds	compound	NOUN
dti-2638	11	32	.	.	PUNCT
dti-2638	12	1	these	these	DET
dti-2638	12	2	compounds	compound	NOUN
dti-2638	12	3	were	be	AUX
dti-2638	12	4	evaluated	evaluate	VERB
dti-2638	12	5	for	for	ADP
dti-2638	12	6	their	their	PRON
dti-2638	12	7	in	in	ADP
dti-2638	12	8	vivo	vivo	ADJ
dti-2638	12	9	anti	anti	ADJ
dti-2638	12	10	-	-	ADJ
dti-2638	12	11	pathogenic	pathogenic	ADJ
dti-2638	12	12	activity	activity	NOUN
dti-2638	12	13	by	by	ADP
dti-2638	12	14	challenging	challenge	VERB
dti-2638	12	15	the	the	DET
dti-2638	12	16	model	model	NOUN
dti-2638	12	17	host	host	NOUN
dti-2638	12	18	caenorhabditis	caenorhabditis	PROPN
dti-2638	12	19	elegans	elegan	NOUN
dti-2638	12	20	with	with	ADP
dti-2638	12	21	p.	p.	NOUN
dti-2638	12	22	aeruginosa	aeruginosa	NOUN
dti-2638	12	23	in	in	ADP
dti-2638	12	24	the	the	DET
dti-2638	12	25	presence	presence	NOUN
dti-2638	12	26	or	or	CCONJ
dti-2638	12	27	absence	absence	NOUN
dti-2638	12	28	of	of	ADP
dti-2638	12	29	test	test	NOUN
dti-2638	12	30	compounds	compound	NOUN
dti-2638	12	31	.	.	PUNCT
dti-2638	13	1	survival	survival	NOUN
dti-2638	13	2	of	of	ADP
dti-2638	13	3	the	the	DET
dti-2638	13	4	worm	worm	NOUN
dti-2638	13	5	population	population	NOUN
dti-2638	13	6	in	in	ADP
dti-2638	13	7	24	24	NUM
dti-2638	13	8	-	-	PUNCT
dti-2638	13	9	well	well	NOUN
dti-2638	13	10	assay	assay	NOUN
dti-2638	13	11	plates	plate	NOUN
dti-2638	13	12	was	be	AUX
dti-2638	13	13	monitored	monitor	VERB
dti-2638	13	14	over	over	ADP
dti-2638	13	15	a	a	DET
dti-2638	13	16	period	period	NOUN
dti-2638	13	17	of	of	ADP
dti-2638	13	18	5	5	NUM
dti-2638	13	19	days	day	NOUN
dti-2638	13	20	microscopically	microscopically	ADV
dti-2638	13	21	.	.	PUNCT
dti-2638	14	1	results	result	NOUN
dti-2638	14	2	:	:	PUNCT
dti-2638	14	3	of	of	ADP
dti-2638	14	4	the	the	DET
dti-2638	14	5	96	96	NUM
dti-2638	14	6	predicted	predict	VERB
dti-2638	14	7	lasr	lasr	PROPN
dti-2638	14	8	inhibitors	inhibitor	NOUN
dti-2638	14	9	,	,	PUNCT
dti-2638	14	10	11	11	NUM
dti-2638	14	11	exhibited	exhibit	VERB
dti-2638	14	12	anti	anti	ADJ
dti-2638	14	13	-	-	ADJ
dti-2638	14	14	pseudomonas	pseudomonas	ADJ
dti-2638	14	15	activity	activity	NOUN
dti-2638	14	16	(	(	PUNCT
dti-2638	14	17	23%-96	23%-96	NUM
dti-2638	14	18	%	%	NOUN
dti-2638	14	19	inhibition	inhibition	NOUN
dti-2638	14	20	of	of	ADP
dti-2638	14	21	bacterial	bacterial	ADJ
dti-2638	14	22	virulence	virulence	NOUN
dti-2638	14	23	as	as	ADP
dti-2638	14	24	per	per	ADP
dti-2638	14	25	third	third	ADJ
dti-2638	14	26	-	-	PUNCT
dti-2638	14	27	day	day	NOUN
dti-2638	14	28	end	end	NOUN
dti-2638	14	29	-	-	PUNCT
dti-2638	14	30	point	point	NOUN
dti-2638	14	31	)	)	PUNCT
dti-2638	14	32	at	at	ADP
dti-2638	14	33	25	25	NUM
dti-2638	14	34	-	-	SYM
dti-2638	14	35	50	50	NUM
dti-2638	14	36	µg	µg	NOUN
dti-2638	14	37	/	/	SYM
dti-2638	14	38	ml	ml	NOUN
dti-2638	14	39	.	.	NOUN
dti-2638	14	40	of	of	ADP
dti-2638	14	41	the	the	DET
dti-2638	14	42	85	85	NUM
dti-2638	14	43	predicted	predict	VERB
dti-2638	14	44	nor	nor	CCONJ
dti-2638	14	45	inhibitors	inhibitor	NOUN
dti-2638	14	46	,	,	PUNCT
dti-2638	14	47	8	8	NUM
dti-2638	14	48	exhibited	exhibit	VERB
dti-2638	14	49	antipseudomonas	antipseudomonas	ADJ
dti-2638	14	50	activity	activity	NOUN
dti-2638	14	51	(	(	PUNCT
dti-2638	14	52	40%-85	40%-85	NUM
dti-2638	14	53	%	%	NOUN
dti-2638	14	54	inhibition	inhibition	NOUN
dti-2638	14	55	of	of	ADP
dti-2638	14	56	bacterial	bacterial	ADJ
dti-2638	14	57	virulence	virulence	NOUN
dti-2638	14	58	as	as	ADP
dti-2638	14	59	per	per	ADP
dti-2638	14	60	second	second	ADJ
dti-2638	14	61	-	-	PUNCT
dti-2638	14	62	day	day	NOUN
dti-2638	14	63	end	end	NOUN
dti-2638	14	64	-	-	PUNCT
dti-2638	14	65	point	point	NOUN
dti-2638	14	66	)	)	PUNCT
dti-2638	14	67	at	at	ADP
dti-2638	14	68	25	25	NUM
dti-2638	14	69	-	-	SYM
dti-2638	14	70	50	50	NUM
dti-2638	14	71	µg	µg	NOUN
dti-2638	14	72	/	/	SYM
dti-2638	14	73	ml	ml	NOUN
dti-2638	14	74	.	.	PUNCT
dti-2638	14	75	conclusion	conclusion	NOUN
dti-2638	14	76	:	:	PUNCT
dti-2638	14	77	further	further	ADJ
dti-2638	14	78	investigation	investigation	NOUN
dti-2638	14	79	on	on	ADP
dti-2638	14	80	molecular	molecular	ADJ
dti-2638	14	81	mode	mode	NOUN
dti-2638	14	82	of	of	ADP
dti-2638	14	83	action	action	NOUN
dti-2638	14	84	of	of	ADP
dti-2638	14	85	compounds	compound	NOUN
dti-2638	14	86	found	find	VERB
dti-2638	14	87	active	active	ADJ
dti-2638	14	88	in	in	ADP
dti-2638	14	89	this	this	DET
dti-2638	14	90	study	study	NOUN
dti-2638	14	91	is	be	AUX
dti-2638	14	92	warranted	warrant	VERB
dti-2638	14	93	.	.	PUNCT
dti-2638	15	1	virtual	virtual	ADJ
dti-2638	15	2	screening	screening	NOUN
dti-2638	15	3	can	can	AUX
dti-2638	15	4	be	be	AUX
dti-2638	15	5	said	say	VERB
dti-2638	15	6	to	to	PART
dti-2638	15	7	be	be	AUX
dti-2638	15	8	a	a	DET
dti-2638	15	9	useful	useful	ADJ
dti-2638	15	10	tool	tool	NOUN
dti-2638	15	11	in	in	ADP
dti-2638	15	12	narrowing	narrow	VERB
dti-2638	15	13	down	down	ADP
dti-2638	15	14	the	the	DET
dti-2638	15	15	list	list	NOUN
dti-2638	15	16	of	of	ADP
dti-2638	15	17	compounds	compound	NOUN
dti-2638	15	18	requiring	require	VERB
dti-2638	15	19	actual	actual	ADJ
dti-2638	15	20	wet	wet	ADJ
dti-2638	15	21	-	-	PUNCT
dti-2638	15	22	lab	lab	NOUN
dti-2638	15	23	screening	screening	NOUN
dti-2638	15	24	,	,	PUNCT
dti-2638	15	25	saving	save	VERB
dti-2638	15	26	considerable	considerable	ADJ
dti-2638	15	27	time	time	NOUN
dti-2638	15	28	and	and	CCONJ
dti-2638	15	29	efforts	effort	NOUN
dti-2638	15	30	for	for	ADP
dti-2638	15	31	drug	drug	NOUN
dti-2638	15	32	discovery	discovery	NOUN
dti-2638	15	33	.	.	PUNCT
dti-2638	16	1	keywords	keyword	NOUN
dti-2638	16	2	:	:	PUNCT
dti-2638	16	3	antimicrobial	antimicrobial	ADJ
dti-2638	16	4	resistance	resistance	NOUN
dti-2638	16	5	(	(	PUNCT
dti-2638	16	6	amr	amr	NOUN
dti-2638	16	7	)	)	PUNCT
dti-2638	16	8	,	,	PUNCT
dti-2638	16	9	nitric	nitric	ADJ
dti-2638	16	10	oxide	oxide	NOUN
dti-2638	16	11	,	,	PUNCT
dti-2638	16	12	nitrosative	nitrosative	ADJ
dti-2638	16	13	stress	stress	NOUN
dti-2638	16	14	,	,	PUNCT
dti-2638	16	15	priority	priority	NOUN
dti-2638	16	16	pathogen	pathogen	NOUN
dti-2638	16	17	,	,	PUNCT
dti-2638	16	18	pseudomonas	pseudomona	NOUN
dti-2638	16	19	aeruginosa	aeruginosa	NOUN
dti-2638	16	20	,	,	PUNCT
dti-2638	16	21	quorum	quorum	VERB
dti-2638	16	22	sensing	sense	VERB
dti-2638	16	23	(	(	PUNCT
dti-2638	16	24	qs	qs	NOUN
dti-2638	16	25	)	)	PUNCT
dti-2638	16	26	,	,	PUNCT
dti-2638	16	27	virulence	virulence	NOUN
dti-2638	16	28	received	receive	VERB
dti-2638	16	29	:	:	PUNCT
dti-2638	16	30	july	july	PROPN
dti-2638	16	31	20	20	NUM
dti-2638	16	32	,	,	PUNCT
dti-2638	16	33	2023	2023	NUM
dti-2638	16	34	accepted	accept	VERB
dti-2638	16	35	:	:	PUNCT
dti-2638	16	36	september	september	PROPN
dti-2638	16	37	4	4	NUM
dti-2638	16	38	,	,	PUNCT
dti-2638	16	39	2023	2023	NUM
dti-2638	16	40	published	publish	VERB
dti-2638	16	41	online	online	ADV
dti-2638	16	42	:	:	PUNCT
dti-2638	16	43	september	september	PROPN
dti-2638	16	44	28	28	NUM
dti-2638	16	45	,	,	PUNCT
dti-2638	16	46	2023	2023	NUM
dti-2638	16	47	this	this	DET
dti-2638	16	48	article	article	NOUN
dti-2638	16	49	includes	include	VERB
dti-2638	16	50	supplementary	supplementary	ADJ
dti-2638	16	51	material	material	NOUN
dti-2638	16	52	corresponding	corresponding	ADJ
dti-2638	16	53	author	author	NOUN
dti-2638	16	54	:	:	PUNCT
dti-2638	16	55	vijay	vijay	PROPN
dti-2638	16	56	kothari	kothari	PROPN
dti-2638	16	57	institute	institute	PROPN
dti-2638	16	58	of	of	ADP
dti-2638	16	59	science	science	PROPN
dti-2638	16	60	,	,	PUNCT
dti-2638	16	61	nirma	nirma	VERB
dti-2638	16	62	university	university	NOUN
dti-2638	16	63	s	s	PROPN
dti-2638	16	64	-	-	PUNCT
dti-2638	16	65	g	g	NOUN
dti-2638	16	66	highway	highway	NOUN
dti-2638	16	67	,	,	PUNCT
dti-2638	16	68	ahmedabad-382481	ahmedabad-382481	ADJ
dti-2638	16	69	india	india	PROPN
dti-2638	16	70	vijay23112004@yahoo.co.in	vijay23112004@yahoo.co.in	PROPN
dti-2638	16	71	;	;	PUNCT
dti-2638	16	72	vijay.kothari@nirmauni.ac.in	vijay.kothari@nirmauni.ac.in	NUM
dti-2638	16	73	bryan	bryan	PROPN
dti-2638	16	74	cox	cox	PROPN
dti-2638	16	75	’s	’s	PART
dti-2638	16	76	affiliation	affiliation	NOUN
dti-2638	16	77	at	at	ADP
dti-2638	16	78	the	the	DET
dti-2638	16	79	time	time	NOUN
dti-2638	16	80	of	of	ADP
dti-2638	16	81	study	study	NOUN
dti-2638	16	82	was	be	AUX
dti-2638	16	83	atomwise	atomwise	PROPN
dti-2638	16	84	inc	inc	PROPN
dti-2638	16	85	.	.	PROPN
dti-2638	16	86	also	also	ADV
dti-2638	16	87	published	publish	VERB
dti-2638	16	88	a	a	DET
dti-2638	16	89	global	global	ADJ
dti-2638	16	90	action	action	NOUN
dti-2638	16	91	plan	plan	NOUN
dti-2638	16	92	on	on	ADP
dti-2638	16	93	amr	amr	PROPN
dti-2638	16	94	in	in	ADP
dti-2638	16	95	2015	2015	NUM
dti-2638	16	96	.	.	PUNCT
dti-2638	17	1	as	as	ADP
dti-2638	17	2	per	per	ADP
dti-2638	17	3	the	the	DET
dti-2638	17	4	indian	indian	ADJ
dti-2638	17	5	national	national	ADJ
dti-2638	17	6	action	action	NOUN
dti-2638	17	7	plan	plan	NOUN
dti-2638	17	8	on	on	ADP
dti-2638	17	9	antimicrobial	antimicrobial	ADJ
dti-2638	17	10	resistance	resistance	NOUN
dti-2638	17	11	(	(	PUNCT
dti-2638	17	12	nap	nap	NOUN
dti-2638	17	13	-	-	PUNCT
dti-2638	17	14	amr	amr	NOUN
dti-2638	17	15	:	:	PUNCT
dti-2638	17	16	2017	2017	NUM
dti-2638	17	17	-	-	SYM
dti-2638	17	18	2021	2021	NUM
dti-2638	17	19	)	)	PUNCT
dti-2638	17	20	,	,	PUNCT
dti-2638	17	21	india	india	PROPN
dti-2638	17	22	is	be	AUX
dti-2638	17	23	among	among	ADP
dti-2638	17	24	the	the	DET
dti-2638	17	25	nations	nation	NOUN
dti-2638	17	26	with	with	ADP
dti-2638	17	27	the	the	DET
dti-2638	17	28	highest	high	ADJ
dti-2638	17	29	burden	burden	NOUN
dti-2638	17	30	of	of	ADP
dti-2638	17	31	bacterial	bacterial	ADJ
dti-2638	17	32	infections	infection	NOUN
dti-2638	17	33	.	.	PUNCT
dti-2638	18	1	the	the	DET
dti-2638	18	2	crude	crude	ADJ
dti-2638	18	3	mortality	mortality	NOUN
dti-2638	18	4	from	from	ADP
dti-2638	18	5	infectious	infectious	ADJ
dti-2638	18	6	diseases	disease	NOUN
dti-2638	18	7	in	in	ADP
dti-2638	18	8	india	india	PROPN
dti-2638	18	9	today	today	NOUN
dti-2638	18	10	is	be	AUX
dti-2638	18	11	417	417	NUM
dti-2638	18	12	per	per	ADP
dti-2638	18	13	100,000	100,000	NUM
dti-2638	18	14	persons	person	NOUN
dti-2638	18	15	.	.	PUNCT
dti-2638	19	1	the	the	DET
dti-2638	19	2	situation	situation	NOUN
dti-2638	19	3	in	in	ADP
dti-2638	19	4	other	other	ADJ
dti-2638	19	5	developing	develop	VERB
dti-2638	19	6	countries	country	NOUN
dti-2638	19	7	is	be	AUX
dti-2638	19	8	equally	equally	ADV
dti-2638	19	9	grave	grave	ADJ
dti-2638	19	10	.	.	PUNCT
dti-2638	20	1	murray	murray	PROPN
dti-2638	20	2	et	et	PROPN
dti-2638	20	3	al	al	PROPN
dti-2638	20	4	estimated	estimate	VERB
dti-2638	20	5	1.27	1.27	NUM
dti-2638	20	6	million	million	NUM
dti-2638	20	7	deaths	death	NOUN
dti-2638	20	8	attributable	attributable	ADJ
dti-2638	20	9	to	to	ADP
dti-2638	20	10	bacterial	bacterial	ADJ
dti-2638	20	11	amr	amr	NOUN
dti-2638	20	12	in	in	ADP
dti-2638	20	13	2019	2019	NUM
dti-2638	20	14	(	(	PUNCT
dti-2638	20	15	1	1	NUM
dti-2638	20	16	)	)	PUNCT
dti-2638	20	17	.	.	PUNCT
dti-2638	21	1	of	of	ADP
dti-2638	21	2	the	the	DET
dti-2638	21	3	six	six	NUM
dti-2638	21	4	leading	lead	VERB
dti-2638	21	5	pathogens	pathogen	NOUN
dti-2638	21	6	identified	identify	VERB
dti-2638	21	7	by	by	ADP
dti-2638	21	8	them	they	PRON
dti-2638	21	9	responsible	responsible	ADJ
dti-2638	21	10	for	for	ADP
dti-2638	21	11	maximum	maximum	ADJ
dti-2638	21	12	death	death	NOUN
dti-2638	21	13	toll	toll	NOUN
dti-2638	21	14	,	,	PUNCT
dti-2638	21	15	one	one	NUM
dti-2638	21	16	is	be	AUX
dti-2638	21	17	pseudomonas	pseudomona	NOUN
dti-2638	21	18	aeruginosa	aeruginosa	NOUN
dti-2638	21	19	.	.	PUNCT
dti-2638	22	1	it	it	PRON
dti-2638	22	2	is	be	AUX
dti-2638	22	3	among	among	ADP
dti-2638	22	4	the	the	DET
dti-2638	22	5	most	most	ADV
dti-2638	22	6	notorious	notorious	ADJ
dti-2638	22	7	pathogenic	pathogenic	ADJ
dti-2638	22	8	bacteria	bacteria	NOUN
dti-2638	22	9	,	,	PUNCT
dti-2638	22	10	and	and	CCONJ
dti-2638	22	11	its	its	PRON
dti-2638	22	12	carbapenem	carbapenem	NOUN
dti-2638	22	13	-	-	PUNCT
dti-2638	22	14	resistant	resistant	ADJ
dti-2638	22	15	phenotype	phenotype	NOUN
dti-2638	22	16	has	have	AUX
dti-2638	22	17	been	be	AUX
dti-2638	22	18	listed	list	VERB
dti-2638	22	19	by	by	ADP
dti-2638	22	20	the	the	DET
dti-2638	22	21	who	who	PRON
dti-2638	22	22	among	among	ADP
dti-2638	22	23	priority	priority	NOUN
dti-2638	22	24	pathogens	pathogen	NOUN
dti-2638	22	25	for	for	ADP
dti-2638	22	26	the	the	DET
dti-2638	22	27	development	development	NOUN
dti-2638	22	28	of	of	ADP
dti-2638	22	29	new	new	ADJ
dti-2638	22	30	antibiotics	antibiotic	NOUN
dti-2638	22	31	(	(	PUNCT
dti-2638	22	32	online	online	ADJ
dti-2638	22	33	)	)	PUNCT
dti-2638	22	34	.	.	PUNCT
dti-2638	23	1	antibiotic	antibiotic	ADJ
dti-2638	23	2	-	-	PUNCT
dti-2638	23	3	resistant	resistant	ADJ
dti-2638	23	4	p.	p.	NOUN
dti-2638	23	5	aeruginosa	aeruginosa	NOUN
dti-2638	23	6	has	have	AUX
dti-2638	23	7	been	be	AUX
dti-2638	23	8	listed	list	VERB
dti-2638	23	9	as	as	ADP
dti-2638	23	10	an	an	DET
dti-2638	23	11	important	important	ADJ
dti-2638	23	12	pathogen	pathogen	NOUN
dti-2638	23	13	by	by	ADP
dti-2638	23	14	the	the	DET
dti-2638	23	15	u.s	u.s	PROPN
dti-2638	23	16	.	.	PROPN
dti-2638	23	17	centers	center	NOUN
dti-2638	23	18	for	for	ADP
dti-2638	23	19	disease	disease	NOUN
dti-2638	23	20	control	control	NOUN
dti-2638	23	21	and	and	CCONJ
dti-2638	23	22	prevention	prevention	NOUN
dti-2638	23	23	(	(	PUNCT
dti-2638	23	24	cdc	cdc	PROPN
dti-2638	23	25	)	)	PUNCT
dti-2638	23	26	(	(	PUNCT
dti-2638	23	27	online	online	INTJ
dti-2638	23	28	)	)	PUNCT
dti-2638	23	29	as	as	ADV
dti-2638	23	30	well	well	ADV
dti-2638	23	31	as	as	ADP
dti-2638	23	32	the	the	DET
dti-2638	23	33	department	department	NOUN
dti-2638	23	34	of	of	ADP
dti-2638	23	35	biotechnology	biotechnology	NOUN
dti-2638	23	36	,	,	PUNCT
dti-2638	23	37	india	india	PROPN
dti-2638	23	38	(	(	PUNCT
dti-2638	23	39	dbt	dbt	PROPN
dti-2638	23	40	)	)	PUNCT
dti-2638	23	41	(	(	PUNCT
dti-2638	23	42	online	online	NOUN
dti-2638	23	43	)	)	PUNCT
dti-2638	23	44	against	against	ADP
dti-2638	23	45	which	which	PRON
dti-2638	23	46	new	new	ADJ
dti-2638	23	47	antimicrobials	antimicrobial	NOUN
dti-2638	23	48	are	be	AUX
dti-2638	23	49	urgently	urgently	ADV
dti-2638	23	50	required	require	VERB
dti-2638	23	51	.	.	PUNCT
dti-2638	24	1	introduction	introduction	NOUN
dti-2638	24	2	antimicrobial	antimicrobial	ADJ
dti-2638	24	3	resistance	resistance	NOUN
dti-2638	24	4	(	(	PUNCT
dti-2638	24	5	amr	amr	NOUN
dti-2638	24	6	)	)	PUNCT
dti-2638	24	7	among	among	ADP
dti-2638	24	8	infectious	infectious	ADJ
dti-2638	24	9	bacteria	bacteria	NOUN
dti-2638	24	10	has	have	AUX
dti-2638	24	11	emerged	emerge	VERB
dti-2638	24	12	as	as	ADP
dti-2638	24	13	a	a	DET
dti-2638	24	14	healthcare	healthcare	NOUN
dti-2638	24	15	challenge	challenge	NOUN
dti-2638	24	16	of	of	ADP
dti-2638	24	17	global	global	ADJ
dti-2638	24	18	concern	concern	NOUN
dti-2638	24	19	(	(	PUNCT
dti-2638	24	20	online	online	ADJ
dti-2638	24	21	)	)	PUNCT
dti-2638	24	22	.	.	PUNCT
dti-2638	25	1	the	the	DET
dti-2638	25	2	world	world	PROPN
dti-2638	25	3	health	health	PROPN
dti-2638	25	4	organization	organization	NOUN
dti-2638	25	5	(	(	PUNCT
dti-2638	25	6	who	who	PRON
dti-2638	25	7	)	)	PUNCT
dti-2638	25	8	has	have	VERB
dti-2638	25	9	https://doi.org/10.33393/dti.2023.2638	https://doi.org/10.33393/dti.2023.2638	PROPN
dti-2638	25	10	https://doi.org/dti.2023.2522	https://doi.org/dti.2023.2522	PROPN
dti-2638	25	11	https://creativecommons.org/licenses/by-nc/4.0/legalcode	https://creativecommons.org/licenses/by-nc/4.0/legalcode	PROPN
dti-2638	25	12	https://www.who.int/medicines/publications/who-ppl-short_summary_25feb-et_nm_who.pdf	https://www.who.int/medicines/publications/who-ppl-short_summary_25feb-et_nm_who.pdf	NOUN
dti-2638	25	13	https://www.cdc.gov/drugresistance/biggest-threats.html	https://www.cdc.gov/drugresistance/biggest-threats.html	PART
dti-2638	25	14	https://dbtindia.gov.in/sites/default/files/ippl_final.pdf	https://dbtindia.gov.in/sites/default/files/ippl_final.pdf	X
dti-2638	25	15	https://amr-review.org/	https://amr-review.org/	VERB
dti-2638	25	16	small	small	ADJ
dti-2638	25	17	-	-	PUNCT
dti-2638	25	18	molecule	molecule	NOUN
dti-2638	25	19	inhibitors	inhibitor	NOUN
dti-2638	25	20	of	of	ADP
dti-2638	25	21	pseudomonas	pseudomona	NOUN
dti-2638	25	22	aeruginosa	aeruginosa	NOUN
dti-2638	25	23	lasr	lasr	PROPN
dti-2638	25	24	or	or	CCONJ
dti-2638	25	25	nor102	nor102	PROPN
dti-2638	25	26	©	©	PROPN
dti-2638	25	27	2023	2023	NUM
dti-2638	25	28	the	the	DET
dti-2638	25	29	authors	author	NOUN
dti-2638	25	30	.	.	PUNCT
dti-2638	26	1	drug	drug	NOUN
dti-2638	26	2	target	target	NOUN
dti-2638	26	3	insights	insight	NOUN
dti-2638	26	4	issn	issn	VERB
dti-2638	26	5	1177	1177	NUM
dti-2638	26	6	-	-	SYM
dti-2638	26	7	3928	3928	NUM
dti-2638	26	8	www.aboutscience.eu/dti	www.aboutscience.eu/dti	VERB
dti-2638	26	9	the	the	DET
dti-2638	26	10	pipeline	pipeline	NOUN
dti-2638	26	11	for	for	ADP
dti-2638	26	12	new	new	ADJ
dti-2638	26	13	antibiotics	antibiotic	NOUN
dti-2638	26	14	does	do	AUX
dti-2638	26	15	not	not	PART
dti-2638	26	16	contain	contain	VERB
dti-2638	26	17	sufficient	sufficient	ADJ
dti-2638	26	18	number	number	NOUN
dti-2638	26	19	of	of	ADP
dti-2638	26	20	promising	promising	ADJ
dti-2638	26	21	candidates	candidate	NOUN
dti-2638	26	22	(	(	PUNCT
dti-2638	26	23	2	2	NUM
dti-2638	26	24	)	)	PUNCT
dti-2638	26	25	.	.	PUNCT
dti-2638	27	1	there	there	PRON
dti-2638	27	2	is	be	VERB
dti-2638	27	3	a	a	DET
dti-2638	27	4	dearth	dearth	NOUN
dti-2638	27	5	of	of	ADP
dti-2638	27	6	novel	novel	ADJ
dti-2638	27	7	antibacterial	antibacterial	ADJ
dti-2638	27	8	leads	lead	NOUN
dti-2638	27	9	as	as	ADV
dti-2638	27	10	well	well	ADV
dti-2638	27	11	as	as	ADP
dti-2638	27	12	targets	target	NOUN
dti-2638	27	13	(	(	PUNCT
dti-2638	27	14	3,4	3,4	NUM
dti-2638	27	15	)	)	PUNCT
dti-2638	27	16	.	.	PUNCT
dti-2638	28	1	identification	identification	NOUN
dti-2638	28	2	and	and	CCONJ
dti-2638	28	3	validation	validation	NOUN
dti-2638	28	4	of	of	ADP
dti-2638	28	5	new	new	ADJ
dti-2638	28	6	targets	target	NOUN
dti-2638	28	7	in	in	ADP
dti-2638	28	8	important	important	ADJ
dti-2638	28	9	pathogens	pathogen	NOUN
dti-2638	28	10	is	be	AUX
dti-2638	28	11	of	of	ADP
dti-2638	28	12	utmost	utmost	ADJ
dti-2638	28	13	significance	significance	NOUN
dti-2638	28	14	(	(	PUNCT
dti-2638	28	15	5,6	5,6	NUM
dti-2638	28	16	)	)	PUNCT
dti-2638	28	17	.	.	PUNCT
dti-2638	29	1	conventional	conventional	ADJ
dti-2638	29	2	bactericidal	bactericidal	ADJ
dti-2638	29	3	antibiotics	antibiotic	NOUN
dti-2638	29	4	attack	attack	NOUN
dti-2638	29	5	a	a	DET
dti-2638	29	6	very	very	ADV
dti-2638	29	7	narrow	narrow	ADJ
dti-2638	29	8	range	range	NOUN
dti-2638	29	9	of	of	ADP
dti-2638	29	10	targets	target	NOUN
dti-2638	29	11	in	in	ADP
dti-2638	29	12	susceptible	susceptible	ADJ
dti-2638	29	13	bacteria	bacteria	NOUN
dti-2638	29	14	,	,	PUNCT
dti-2638	29	15	for	for	ADP
dti-2638	29	16	example	example	NOUN
dti-2638	29	17	,	,	PUNCT
dti-2638	29	18	cell	cell	NOUN
dti-2638	29	19	wall	wall	NOUN
dti-2638	29	20	synthesis	synthesis	NOUN
dti-2638	29	21	,	,	PUNCT
dti-2638	29	22	protein	protein	NOUN
dti-2638	29	23	synthesis	synthesis	NOUN
dti-2638	29	24	,	,	PUNCT
dti-2638	29	25	nucleic	nucleic	ADJ
dti-2638	29	26	acid	acid	NOUN
dti-2638	29	27	synthesis	synthesis	NOUN
dti-2638	29	28	,	,	PUNCT
dti-2638	29	29	etc	etc	X
dti-2638	29	30	.	.	X
dti-2638	30	1	since	since	SCONJ
dti-2638	30	2	the	the	DET
dti-2638	30	3	past	past	ADJ
dti-2638	30	4	decade	decade	NOUN
dti-2638	30	5	,	,	PUNCT
dti-2638	30	6	there	there	PRON
dti-2638	30	7	has	have	AUX
dti-2638	30	8	been	be	AUX
dti-2638	30	9	much	much	ADJ
dti-2638	30	10	interest	interest	NOUN
dti-2638	30	11	in	in	ADP
dti-2638	30	12	the	the	DET
dti-2638	30	13	research	research	NOUN
dti-2638	30	14	community	community	NOUN
dti-2638	30	15	regarding	regard	VERB
dti-2638	30	16	discovery	discovery	NOUN
dti-2638	30	17	of	of	ADP
dti-2638	30	18	anti	anti	ADJ
dti-2638	30	19	-	-	ADJ
dti-2638	30	20	virulence	virulence	ADJ
dti-2638	30	21	molecules	molecule	NOUN
dti-2638	30	22	,	,	PUNCT
dti-2638	30	23	which	which	PRON
dti-2638	30	24	may	may	AUX
dti-2638	30	25	attenuate	attenuate	VERB
dti-2638	30	26	the	the	DET
dti-2638	30	27	bacterial	bacterial	ADJ
dti-2638	30	28	virulence	virulence	NOUN
dti-2638	30	29	without	without	ADP
dti-2638	30	30	necessarily	necessarily	ADV
dti-2638	30	31	killing	kill	VERB
dti-2638	30	32	them	they	PRON
dti-2638	30	33	.	.	PUNCT
dti-2638	31	1	such	such	ADJ
dti-2638	31	2	‘	'	PUNCT
dti-2638	31	3	pathoblockers	pathoblocker	NOUN
dti-2638	31	4	’	'	PUNCT
dti-2638	31	5	are	be	AUX
dti-2638	31	6	expected	expect	VERB
dti-2638	31	7	to	to	PART
dti-2638	31	8	compromise	compromise	VERB
dti-2638	31	9	the	the	DET
dti-2638	31	10	ability	ability	NOUN
dti-2638	31	11	of	of	ADP
dti-2638	31	12	the	the	DET
dti-2638	31	13	pathogen	pathogen	NOUN
dti-2638	31	14	to	to	PART
dti-2638	31	15	damage	damage	VERB
dti-2638	31	16	the	the	DET
dti-2638	31	17	host	host	NOUN
dti-2638	31	18	,	,	PUNCT
dti-2638	31	19	by	by	ADP
dti-2638	31	20	exerting	exert	VERB
dti-2638	31	21	their	their	PRON
dti-2638	31	22	effect	effect	NOUN
dti-2638	31	23	on	on	ADP
dti-2638	31	24	nonessential	nonessential	ADJ
dti-2638	31	25	targets	target	NOUN
dti-2638	31	26	such	such	ADJ
dti-2638	31	27	as	as	ADP
dti-2638	31	28	bacterial	bacterial	ADJ
dti-2638	31	29	quorum	quorum	NOUN
dti-2638	31	30	sensing	sense	VERB
dti-2638	31	31	(	(	PUNCT
dti-2638	31	32	qs	qs	NOUN
dti-2638	31	33	)	)	PUNCT
dti-2638	31	34	(	(	PUNCT
dti-2638	31	35	7	7	NUM
dti-2638	31	36	)	)	PUNCT
dti-2638	31	37	,	,	PUNCT
dti-2638	31	38	stress	stress	NOUN
dti-2638	31	39	-	-	PUNCT
dti-2638	31	40	response	response	NOUN
dti-2638	31	41	machinery	machinery	NOUN
dti-2638	31	42	(	(	PUNCT
dti-2638	31	43	8)	8)	NUM
dti-2638	31	44	,	,	PUNCT
dti-2638	31	45	metal	metal	NOUN
dti-2638	31	46	homeostasis	homeostasis	NOUN
dti-2638	31	47	(	(	PUNCT
dti-2638	31	48	9,10	9,10	NUM
dti-2638	31	49	)	)	PUNCT
dti-2638	31	50	,	,	PUNCT
dti-2638	31	51	etc	etc	X
dti-2638	31	52	.	.	X
dti-2638	31	53	the	the	DET
dti-2638	31	54	next	next	ADJ
dti-2638	31	55	-	-	PUNCT
dti-2638	31	56	generation	generation	NOUN
dti-2638	31	57	antibacterials	antibacterial	NOUN
dti-2638	31	58	preferably	preferably	ADV
dti-2638	31	59	should	should	AUX
dti-2638	31	60	be	be	AUX
dti-2638	31	61	attacking	attack	VERB
dti-2638	31	62	such	such	ADJ
dti-2638	31	63	hitherto	hitherto	NOUN
dti-2638	31	64	unexplored	unexplored	ADJ
dti-2638	31	65	/	/	SYM
dti-2638	31	66	underexplored	underexplored	ADJ
dti-2638	31	67	targets	target	NOUN
dti-2638	31	68	in	in	ADP
dti-2638	31	69	pathogenic	pathogenic	ADJ
dti-2638	31	70	bacteria	bacteria	NOUN
dti-2638	31	71	(	(	PUNCT
dti-2638	31	72	11	11	NUM
dti-2638	31	73	-	-	SYM
dti-2638	31	74	13	13	NUM
dti-2638	31	75	)	)	PUNCT
dti-2638	31	76	.	.	PUNCT
dti-2638	32	1	proper	proper	ADJ
dti-2638	32	2	functioning	functioning	NOUN
dti-2638	32	3	of	of	ADP
dti-2638	32	4	the	the	DET
dti-2638	32	5	chemical	chemical	NOUN
dti-2638	32	6	signal	signal	NOUN
dti-2638	32	7	-	-	PUNCT
dti-2638	32	8	based	base	VERB
dti-2638	32	9	intercellular	intercellular	ADJ
dti-2638	32	10	communication	communication	NOUN
dti-2638	32	11	,	,	PUNCT
dti-2638	32	12	known	know	VERB
dti-2638	32	13	as	as	ADP
dti-2638	32	14	qs	qs	PROPN
dti-2638	32	15	,	,	PUNCT
dti-2638	32	16	is	be	AUX
dti-2638	32	17	crucial	crucial	ADJ
dti-2638	32	18	for	for	ADP
dti-2638	32	19	sufficient	sufficient	ADJ
dti-2638	32	20	expression	expression	NOUN
dti-2638	32	21	of	of	ADP
dti-2638	32	22	virulence	virulence	NOUN
dti-2638	32	23	in	in	ADP
dti-2638	32	24	pathogens	pathogen	NOUN
dti-2638	32	25	like	like	ADP
dti-2638	32	26	p.	p.	PROPN
dti-2638	32	27	aeruginosa	aeruginosa	PROPN
dti-2638	32	28	,	,	PUNCT
dti-2638	32	29	as	as	SCONJ
dti-2638	32	30	qs	qs	PROPN
dti-2638	32	31	is	be	AUX
dti-2638	32	32	an	an	DET
dti-2638	32	33	effective	effective	ADJ
dti-2638	32	34	mechanism	mechanism	NOUN
dti-2638	32	35	for	for	ADP
dti-2638	32	36	regulating	regulate	VERB
dti-2638	32	37	expression	expression	NOUN
dti-2638	32	38	of	of	ADP
dti-2638	32	39	multiple	multiple	ADJ
dti-2638	32	40	genes	gene	NOUN
dti-2638	32	41	associated	associate	VERB
dti-2638	32	42	with	with	ADP
dti-2638	32	43	a	a	DET
dti-2638	32	44	multitude	multitude	NOUN
dti-2638	32	45	of	of	ADP
dti-2638	32	46	functions	function	NOUN
dti-2638	32	47	(	(	PUNCT
dti-2638	32	48	14	14	NUM
dti-2638	32	49	)	)	PUNCT
dti-2638	32	50	.	.	PUNCT
dti-2638	33	1	interrupting	interrupt	VERB
dti-2638	33	2	bacterial	bacterial	ADJ
dti-2638	33	3	qs	qs	NOUN
dti-2638	33	4	can	can	AUX
dti-2638	33	5	be	be	AUX
dti-2638	33	6	an	an	DET
dti-2638	33	7	effective	effective	ADJ
dti-2638	33	8	strategy	strategy	NOUN
dti-2638	33	9	to	to	PART
dti-2638	33	10	combat	combat	VERB
dti-2638	33	11	pathogens	pathogen	NOUN
dti-2638	33	12	(	(	PUNCT
dti-2638	33	13	15,16	15,16	NUM
dti-2638	33	14	)	)	PUNCT
dti-2638	33	15	.	.	PUNCT
dti-2638	34	1	qs	qs	PROPN
dti-2638	34	2	consists	consist	NOUN
dti-2638	34	3	of	of	ADP
dti-2638	34	4	two	two	NUM
dti-2638	34	5	components	component	NOUN
dti-2638	34	6	:	:	PUNCT
dti-2638	34	7	signal	signal	NOUN
dti-2638	34	8	generation	generation	NOUN
dti-2638	34	9	and	and	CCONJ
dti-2638	34	10	signal	signal	ADJ
dti-2638	34	11	response	response	NOUN
dti-2638	34	12	,	,	PUNCT
dti-2638	34	13	respectively	respectively	ADV
dti-2638	34	14	,	,	PUNCT
dti-2638	34	15	encoded	encode	VERB
dti-2638	34	16	by	by	ADP
dti-2638	34	17	luxi	luxi	NOUN
dti-2638	34	18	and	and	CCONJ
dti-2638	34	19	luxr	luxr	NOUN
dti-2638	34	20	homologues	homologue	NOUN
dti-2638	34	21	(	(	PUNCT
dti-2638	34	22	17,18	17,18	NUM
dti-2638	34	23	)	)	PUNCT
dti-2638	34	24	.	.	PUNCT
dti-2638	35	1	inhibiting	inhibit	VERB
dti-2638	35	2	the	the	DET
dti-2638	35	3	‘	'	PUNCT
dti-2638	35	4	signal	signal	ADJ
dti-2638	35	5	response	response	NOUN
dti-2638	35	6	’	'	PUNCT
dti-2638	35	7	component	component	NOUN
dti-2638	35	8	of	of	ADP
dti-2638	35	9	qs	qs	PROPN
dti-2638	35	10	(	(	PUNCT
dti-2638	35	11	e.g.	e.g.	ADV
dti-2638	35	12	lasr	lasr	PROPN
dti-2638	35	13	in	in	ADP
dti-2638	35	14	p.	p.	PROPN
dti-2638	35	15	aeruginosa	aeruginosa	PROPN
dti-2638	35	16	)	)	PUNCT
dti-2638	35	17	can	can	AUX
dti-2638	35	18	notably	notably	ADV
dti-2638	35	19	compromise	compromise	VERB
dti-2638	35	20	their	their	PRON
dti-2638	35	21	ability	ability	NOUN
dti-2638	35	22	to	to	PART
dti-2638	35	23	exert	exert	VERB
dti-2638	35	24	collective	collective	ADJ
dti-2638	35	25	behaviour	behaviour	NOUN
dti-2638	35	26	in	in	ADP
dti-2638	35	27	response	response	NOUN
dti-2638	35	28	to	to	ADP
dti-2638	35	29	environmental	environmental	ADJ
dti-2638	35	30	changes	change	NOUN
dti-2638	35	31	or	or	CCONJ
dti-2638	35	32	host	host	NOUN
dti-2638	35	33	defence	defence	NOUN
dti-2638	35	34	.	.	PUNCT
dti-2638	36	1	p.	p.	NOUN
dti-2638	36	2	aeruginosa	aeruginosa	PROPN
dti-2638	36	3	regulates	regulate	VERB
dti-2638	36	4	its	its	PRON
dti-2638	36	5	drug	drug	NOUN
dti-2638	36	6	resistance	resistance	NOUN
dti-2638	36	7	and	and	CCONJ
dti-2638	36	8	pathogenicity	pathogenicity	NOUN
dti-2638	36	9	through	through	ADP
dti-2638	36	10	multiple	multiple	ADJ
dti-2638	36	11	qs	qs	NOUN
dti-2638	36	12	mechanisms	mechanism	NOUN
dti-2638	36	13	including	include	VERB
dti-2638	36	14	the	the	DET
dti-2638	36	15	lasi	lasi	PROPN
dti-2638	36	16	/	/	SYM
dti-2638	36	17	r	r	PROPN
dti-2638	36	18	,	,	PUNCT
dti-2638	36	19	rhli	rhli	NOUN
dti-2638	36	20	/	/	SYM
dti-2638	36	21	r	r	NOUN
dti-2638	36	22	,	,	PUNCT
dti-2638	36	23	and	and	CCONJ
dti-2638	36	24	pqs	pqs	PROPN
dti-2638	36	25	/	/	SYM
dti-2638	36	26	mvfr	mvfr	NOUN
dti-2638	36	27	systems	system	NOUN
dti-2638	36	28	.	.	PUNCT
dti-2638	37	1	targeting	target	VERB
dti-2638	37	2	one	one	NUM
dti-2638	37	3	or	or	CCONJ
dti-2638	37	4	more	more	ADJ
dti-2638	37	5	of	of	ADP
dti-2638	37	6	these	these	DET
dti-2638	37	7	qs	qs	PROPN
dti-2638	37	8	systems	system	NOUN
dti-2638	37	9	may	may	AUX
dti-2638	37	10	prove	prove	VERB
dti-2638	37	11	an	an	DET
dti-2638	37	12	effective	effective	ADJ
dti-2638	37	13	way	way	NOUN
dti-2638	37	14	of	of	ADP
dti-2638	37	15	dealing	deal	VERB
dti-2638	37	16	with	with	ADP
dti-2638	37	17	p.	p.	NOUN
dti-2638	37	18	aeruginosa	aeruginosa	PROPN
dti-2638	37	19	infections	infection	NOUN
dti-2638	37	20	(	(	PUNCT
dti-2638	37	21	19	19	NUM
dti-2638	37	22	)	)	PUNCT
dti-2638	37	23	.	.	PUNCT
dti-2638	38	1	owing	owe	VERB
dti-2638	38	2	to	to	ADP
dti-2638	38	3	the	the	DET
dti-2638	38	4	important	important	ADJ
dti-2638	38	5	role	role	NOUN
dti-2638	38	6	of	of	ADP
dti-2638	38	7	las	las	NOUN
dti-2638	38	8	system	system	NOUN
dti-2638	38	9	in	in	ADP
dti-2638	38	10	overall	overall	ADJ
dti-2638	38	11	qs	qs	NOUN
dti-2638	38	12	circuit	circuit	NOUN
dti-2638	38	13	of	of	ADP
dti-2638	38	14	p.	p.	PROPN
dti-2638	38	15	aeruginosa	aeruginosa	PROPN
dti-2638	38	16	,	,	PUNCT
dti-2638	38	17	its	its	PRON
dti-2638	38	18	receptor	receptor	NOUN
dti-2638	38	19	protein	protein	NOUN
dti-2638	38	20	lasr	lasr	PROPN
dti-2638	38	21	is	be	AUX
dti-2638	38	22	believed	believe	VERB
dti-2638	38	23	to	to	PART
dti-2638	38	24	be	be	AUX
dti-2638	38	25	a	a	DET
dti-2638	38	26	plausible	plausible	ADJ
dti-2638	38	27	anti	anti	ADJ
dti-2638	38	28	-	-	ADJ
dti-2638	38	29	virulence	virulence	ADJ
dti-2638	38	30	target	target	NOUN
dti-2638	38	31	(	(	PUNCT
dti-2638	38	32	20	20	NUM
dti-2638	38	33	)	)	PUNCT
dti-2638	38	34	.	.	PUNCT
dti-2638	39	1	lasr	lasr	PROPN
dti-2638	39	2	is	be	AUX
dti-2638	39	3	a	a	DET
dti-2638	39	4	transcriptional	transcriptional	ADJ
dti-2638	39	5	activator	activator	NOUN
dti-2638	39	6	of	of	ADP
dti-2638	39	7	various	various	ADJ
dti-2638	39	8	virulenceassociated	virulenceassociate	VERB
dti-2638	39	9	genes	gene	NOUN
dti-2638	39	10	in	in	ADP
dti-2638	39	11	p.	p.	PROPN
dti-2638	39	12	aeruginosa	aeruginosa	PROPN
dti-2638	39	13	,	,	PUNCT
dti-2638	39	14	which	which	PRON
dti-2638	39	15	recognizes	recognize	VERB
dti-2638	39	16	a	a	DET
dti-2638	39	17	specific	specific	ADJ
dti-2638	39	18	signal	signal	NOUN
dti-2638	39	19	molecule	molecule	NOUN
dti-2638	39	20	,	,	PUNCT
dti-2638	39	21	namely	namely	ADV
dti-2638	39	22	n-(3	n-(3	NOUN
dti-2638	39	23	-	-	PUNCT
dti-2638	39	24	oxo	oxo	NOUN
dti-2638	39	25	-	-	PUNCT
dti-2638	39	26	dodecanoyl)-l	dodecanoyl)-l	NOUN
dti-2638	39	27	-	-	PUNCT
dti-2638	39	28	homoserine	homoserine	NOUN
dti-2638	39	29	lactone	lactone	NOUN
dti-2638	39	30	(	(	PUNCT
dti-2638	39	31	3o	3o	NUM
dti-2638	39	32	-	-	PUNCT
dti-2638	39	33	c12	c12	NOUN
dti-2638	39	34	-	-	PUNCT
dti-2638	39	35	hsl	hsl	NOUN
dti-2638	39	36	)	)	PUNCT
dti-2638	39	37	(	(	PUNCT
dti-2638	39	38	21	21	NUM
dti-2638	39	39	)	)	PUNCT
dti-2638	39	40	.	.	PUNCT
dti-2638	40	1	the	the	DET
dti-2638	40	2	lasr-3o	lasr-3o	NOUN
dti-2638	40	3	-	-	PUNCT
dti-2638	40	4	c12	c12	NOUN
dti-2638	40	5	-	-	PUNCT
dti-2638	40	6	hsl	hsl	NOUN
dti-2638	40	7	complex	complex	ADJ
dti-2638	40	8	triggers	trigger	VERB
dti-2638	40	9	the	the	DET
dti-2638	40	10	expression	expression	NOUN
dti-2638	40	11	of	of	ADP
dti-2638	40	12	multiple	multiple	ADJ
dti-2638	40	13	qs	qs	ADJ
dti-2638	40	14	-	-	PUNCT
dti-2638	40	15	regulated	regulated	ADJ
dti-2638	40	16	genes	gene	NOUN
dti-2638	40	17	.	.	PUNCT
dti-2638	41	1	potential	potential	ADJ
dti-2638	41	2	lasr	lasr	PROPN
dti-2638	41	3	inhibitors	inhibitor	NOUN
dti-2638	41	4	either	either	CCONJ
dti-2638	41	5	may	may	AUX
dti-2638	41	6	prevent	prevent	VERB
dti-2638	41	7	its	its	PRON
dti-2638	41	8	binding	binding	NOUN
dti-2638	41	9	with	with	ADP
dti-2638	41	10	its	its	PRON
dti-2638	41	11	natural	natural	ADJ
dti-2638	41	12	ligand	ligand	NOUN
dti-2638	41	13	or	or	CCONJ
dti-2638	41	14	compromise	compromise	VERB
dti-2638	41	15	its	its	PRON
dti-2638	41	16	ability	ability	NOUN
dti-2638	41	17	to	to	PART
dti-2638	41	18	affect	affect	VERB
dti-2638	41	19	expression	expression	NOUN
dti-2638	41	20	of	of	ADP
dti-2638	41	21	target	target	NOUN
dti-2638	41	22	genes	gene	NOUN
dti-2638	41	23	(	(	PUNCT
dti-2638	41	24	22	22	NUM
dti-2638	41	25	)	)	PUNCT
dti-2638	41	26	.	.	PUNCT
dti-2638	42	1	qs	qs	PART
dti-2638	42	2	not	not	PART
dti-2638	42	3	being	be	AUX
dti-2638	42	4	essential	essential	ADJ
dti-2638	42	5	for	for	ADP
dti-2638	42	6	bacterial	bacterial	ADJ
dti-2638	42	7	survival	survival	NOUN
dti-2638	42	8	,	,	PUNCT
dti-2638	42	9	its	its	PRON
dti-2638	42	10	inhibitors	inhibitor	NOUN
dti-2638	42	11	are	be	AUX
dti-2638	42	12	expected	expect	VERB
dti-2638	42	13	to	to	PART
dti-2638	42	14	exert	exert	VERB
dti-2638	42	15	lesser	less	ADJ
dti-2638	42	16	selection	selection	NOUN
dti-2638	42	17	pressure	pressure	NOUN
dti-2638	42	18	on	on	ADP
dti-2638	42	19	bacterial	bacterial	ADJ
dti-2638	42	20	population	population	NOUN
dti-2638	42	21	with	with	ADP
dti-2638	42	22	respect	respect	NOUN
dti-2638	42	23	to	to	ADP
dti-2638	42	24	development	development	NOUN
dti-2638	42	25	of	of	ADP
dti-2638	42	26	resistant	resistant	ADJ
dti-2638	42	27	phenotypes	phenotype	NOUN
dti-2638	42	28	(	(	PUNCT
dti-2638	42	29	23	23	NUM
dti-2638	42	30	)	)	PUNCT
dti-2638	42	31	.	.	PUNCT
dti-2638	43	1	additionally	additionally	ADV
dti-2638	43	2	,	,	PUNCT
dti-2638	43	3	due	due	ADP
dti-2638	43	4	to	to	ADP
dti-2638	43	5	the	the	DET
dti-2638	43	6	overlap	overlap	NOUN
dti-2638	43	7	in	in	ADP
dti-2638	43	8	qs	qs	PROPN
dti-2638	43	9	systems	system	NOUN
dti-2638	43	10	among	among	ADP
dti-2638	43	11	various	various	ADJ
dti-2638	43	12	gram	gram	NOUN
dti-2638	43	13	-	-	PUNCT
dti-2638	43	14	negative	negative	ADJ
dti-2638	43	15	bacteria	bacteria	NOUN
dti-2638	43	16	(	(	PUNCT
dti-2638	43	17	24	24	NUM
dti-2638	43	18	-	-	SYM
dti-2638	43	19	25	25	NUM
dti-2638	43	20	)	)	PUNCT
dti-2638	43	21	,	,	PUNCT
dti-2638	43	22	inhibitors	inhibitor	NOUN
dti-2638	43	23	effective	effective	ADJ
dti-2638	43	24	against	against	ADP
dti-2638	43	25	one	one	NUM
dti-2638	43	26	gram	gram	NOUN
dti-2638	43	27	-	-	PUNCT
dti-2638	43	28	negative	negative	ADJ
dti-2638	43	29	species	specie	NOUN
dti-2638	43	30	may	may	AUX
dti-2638	43	31	have	have	VERB
dti-2638	43	32	broad	broad	ADJ
dti-2638	43	33	-	-	PUNCT
dti-2638	43	34	spectrum	spectrum	NOUN
dti-2638	43	35	activity	activity	NOUN
dti-2638	43	36	against	against	ADP
dti-2638	43	37	multiple	multiple	ADJ
dti-2638	43	38	other	other	ADJ
dti-2638	43	39	gram	gram	NOUN
dti-2638	43	40	-	-	PUNCT
dti-2638	43	41	negative	negative	ADJ
dti-2638	43	42	pathogens	pathogen	NOUN
dti-2638	43	43	.	.	PUNCT
dti-2638	44	1	pathogens	pathogen	NOUN
dti-2638	44	2	striving	strive	VERB
dti-2638	44	3	to	to	PART
dti-2638	44	4	survive	survive	VERB
dti-2638	44	5	inside	inside	ADP
dti-2638	44	6	a	a	DET
dti-2638	44	7	host	host	NOUN
dti-2638	44	8	body	body	NOUN
dti-2638	44	9	are	be	AUX
dti-2638	44	10	forced	force	VERB
dti-2638	44	11	to	to	PART
dti-2638	44	12	face	face	VERB
dti-2638	44	13	a	a	DET
dti-2638	44	14	variety	variety	NOUN
dti-2638	44	15	of	of	ADP
dti-2638	44	16	stresses	stress	NOUN
dti-2638	44	17	such	such	ADJ
dti-2638	44	18	as	as	ADP
dti-2638	44	19	iron	iron	NOUN
dti-2638	44	20	deprivation	deprivation	NOUN
dti-2638	44	21	,	,	PUNCT
dti-2638	44	22	oxidative	oxidative	ADJ
dti-2638	44	23	stress	stress	NOUN
dti-2638	44	24	,	,	PUNCT
dti-2638	44	25	nitrosative	nitrosative	ADJ
dti-2638	44	26	stress	stress	NOUN
dti-2638	44	27	,	,	PUNCT
dti-2638	44	28	etc	etc	X
dti-2638	44	29	.	.	X
dti-2638	45	1	bacteria	bacteria	NOUN
dti-2638	45	2	employ	employ	VERB
dti-2638	45	3	antioxidant	antioxidant	ADJ
dti-2638	45	4	enzymes	enzyme	NOUN
dti-2638	45	5	to	to	PART
dti-2638	45	6	counter	counter	VERB
dti-2638	45	7	reactive	reactive	ADJ
dti-2638	45	8	oxygen	oxygen	NOUN
dti-2638	45	9	species	specie	NOUN
dti-2638	45	10	,	,	PUNCT
dti-2638	45	11	and	and	CCONJ
dti-2638	45	12	similarly	similarly	ADV
dti-2638	45	13	certain	certain	ADJ
dti-2638	45	14	other	other	ADJ
dti-2638	45	15	enzymes	enzyme	NOUN
dti-2638	45	16	to	to	PART
dti-2638	45	17	counter	counter	VERB
dti-2638	45	18	reactive	reactive	ADJ
dti-2638	45	19	nitrogen	nitrogen	NOUN
dti-2638	45	20	species	specie	NOUN
dti-2638	45	21	(	(	PUNCT
dti-2638	45	22	26	26	NUM
dti-2638	45	23	)	)	PUNCT
dti-2638	45	24	.	.	PUNCT
dti-2638	46	1	from	from	ADP
dti-2638	46	2	the	the	DET
dti-2638	46	3	work	work	NOUN
dti-2638	46	4	done	do	VERB
dti-2638	46	5	in	in	ADP
dti-2638	46	6	our	our	PRON
dti-2638	46	7	lab	lab	NOUN
dti-2638	46	8	as	as	ADV
dti-2638	46	9	well	well	ADV
dti-2638	46	10	as	as	ADP
dti-2638	46	11	literature	literature	NOUN
dti-2638	46	12	survey	survey	NOUN
dti-2638	46	13	,	,	PUNCT
dti-2638	46	14	we	we	PRON
dti-2638	46	15	consider	consider	VERB
dti-2638	46	16	the	the	DET
dti-2638	46	17	components	component	NOUN
dti-2638	46	18	of	of	ADP
dti-2638	46	19	p.	p.	NOUN
dti-2638	46	20	aeruginosa	aeruginosa	NOUN
dti-2638	46	21	genome	genome	NOUN
dti-2638	46	22	involved	involve	VERB
dti-2638	46	23	in	in	ADP
dti-2638	46	24	responding	respond	VERB
dti-2638	46	25	to	to	ADP
dti-2638	46	26	nitrosative	nitrosative	ADJ
dti-2638	46	27	stress	stress	NOUN
dti-2638	46	28	to	to	PART
dti-2638	46	29	be	be	AUX
dti-2638	46	30	potential	potential	ADJ
dti-2638	46	31	targets	target	NOUN
dti-2638	46	32	.	.	PUNCT
dti-2638	47	1	among	among	ADP
dti-2638	47	2	the	the	DET
dti-2638	47	3	components	component	NOUN
dti-2638	47	4	of	of	ADP
dti-2638	47	5	nitrosative	nitrosative	ADJ
dti-2638	47	6	stress	stress	NOUN
dti-2638	47	7	response	response	NOUN
dti-2638	47	8	in	in	ADP
dti-2638	47	9	p.	p.	PROPN
dti-2638	47	10	aeruginosa	aeruginosa	PROPN
dti-2638	47	11	,	,	PUNCT
dti-2638	47	12	one	one	NUM
dti-2638	47	13	important	important	ADJ
dti-2638	47	14	enzyme	enzyme	NOUN
dti-2638	47	15	is	be	AUX
dti-2638	47	16	nitric	nitric	ADJ
dti-2638	47	17	oxide	oxide	NOUN
dti-2638	47	18	reductase	reductase	NOUN
dti-2638	47	19	(	(	PUNCT
dti-2638	47	20	nor	nor	CCONJ
dti-2638	47	21	)	)	PUNCT
dti-2638	47	22	.	.	PUNCT
dti-2638	48	1	this	this	DET
dti-2638	48	2	protein	protein	NOUN
dti-2638	48	3	was	be	AUX
dti-2638	48	4	one	one	NUM
dti-2638	48	5	of	of	ADP
dti-2638	48	6	the	the	DET
dti-2638	48	7	major	major	ADJ
dti-2638	48	8	targets	target	NOUN
dti-2638	48	9	of	of	ADP
dti-2638	48	10	an	an	DET
dti-2638	48	11	antiinfective	antiinfective	ADJ
dti-2638	48	12	polyherbal	polyherbal	ADJ
dti-2638	48	13	formulation	formulation	NOUN
dti-2638	48	14	(	(	PUNCT
dti-2638	48	15	panchvalkal	panchvalkal	NOUN
dti-2638	48	16	)	)	PUNCT
dti-2638	48	17	investigated	investigate	VERB
dti-2638	48	18	by	by	ADP
dti-2638	48	19	us	we	PRON
dti-2638	48	20	in	in	ADP
dti-2638	48	21	the	the	DET
dti-2638	48	22	recent	recent	ADJ
dti-2638	48	23	past	past	NOUN
dti-2638	48	24	(	(	PUNCT
dti-2638	48	25	6,27	6,27	NUM
dti-2638	48	26	)	)	PUNCT
dti-2638	48	27	.	.	PUNCT
dti-2638	49	1	nor	nor	CCONJ
dti-2638	49	2	also	also	ADV
dti-2638	49	3	emerged	emerge	VERB
dti-2638	49	4	among	among	ADP
dti-2638	49	5	the	the	DET
dti-2638	49	6	top	top	NOUN
dti-2638	49	7	differentially	differentially	ADV
dti-2638	49	8	expressed	express	VERB
dti-2638	49	9	genes	gene	NOUN
dti-2638	49	10	in	in	ADP
dti-2638	49	11	p.	p.	PROPN
dti-2638	49	12	aeruginosa	aeruginosa	NOUN
dti-2638	49	13	treated	treat	VERB
dti-2638	49	14	by	by	ADP
dti-2638	49	15	us	we	PRON
dti-2638	49	16	with	with	ADP
dti-2638	49	17	other	other	ADJ
dti-2638	49	18	anti	anti	ADJ
dti-2638	49	19	-	-	ADJ
dti-2638	49	20	virulence	virulence	ADJ
dti-2638	49	21	polyherbal	polyherbal	ADJ
dti-2638	49	22	formulations	formulation	NOUN
dti-2638	49	23	enteropan	enteropan	NOUN
dti-2638	49	24	(	(	PUNCT
dti-2638	49	25	srx15248092	srx15248092	PROPN
dti-2638	49	26	)	)	PUNCT
dti-2638	49	27	or	or	CCONJ
dti-2638	49	28	colloidal	colloidal	NOUN
dti-2638	49	29	silver	silver	NOUN
dti-2638	49	30	(	(	PUNCT
dti-2638	49	31	srx14392191	srx14392191	NOUN
dti-2638	49	32	)	)	PUNCT
dti-2638	49	33	at	at	ADP
dti-2638	49	34	sub	sub	ADJ
dti-2638	49	35	-	-	ADJ
dti-2638	49	36	lethal	lethal	ADJ
dti-2638	49	37	levels	level	NOUN
dti-2638	49	38	.	.	PUNCT
dti-2638	50	1	nor	nor	CCONJ
dti-2638	50	2	is	be	AUX
dti-2638	50	3	an	an	DET
dti-2638	50	4	important	important	ADJ
dti-2638	50	5	detoxifying	detoxify	VERB
dti-2638	50	6	enzyme	enzyme	NOUN
dti-2638	50	7	in	in	ADP
dti-2638	50	8	p.	p.	PROPN
dti-2638	50	9	aeruginosa	aeruginosa	PROPN
dti-2638	50	10	,	,	PUNCT
dti-2638	50	11	which	which	PRON
dti-2638	50	12	is	be	AUX
dti-2638	50	13	crucial	crucial	ADJ
dti-2638	50	14	to	to	ADP
dti-2638	50	15	its	its	PRON
dti-2638	50	16	ability	ability	NOUN
dti-2638	50	17	to	to	PART
dti-2638	50	18	withstand	withstand	VERB
dti-2638	50	19	nitrosative	nitrosative	ADJ
dti-2638	50	20	stress	stress	NOUN
dti-2638	50	21	(	(	PUNCT
dti-2638	50	22	e.g.	e.g.	ADV
dti-2638	50	23	in	in	ADP
dti-2638	50	24	the	the	DET
dti-2638	50	25	form	form	NOUN
dti-2638	50	26	of	of	ADP
dti-2638	50	27	nitric	nitric	ADJ
dti-2638	50	28	oxide	oxide	NOUN
dti-2638	51	1	[	[	X
dti-2638	51	2	no	no	NOUN
dti-2638	51	3	]	]	X
dti-2638	51	4	)	)	PUNCT
dti-2638	51	5	.	.	PUNCT
dti-2638	52	1	nor	nor	CCONJ
dti-2638	52	2	has	have	AUX
dti-2638	52	3	also	also	ADV
dti-2638	52	4	been	be	AUX
dti-2638	52	5	reported	report	VERB
dti-2638	52	6	(	(	PUNCT
dti-2638	52	7	28,29	28,29	NUM
dti-2638	52	8	)	)	PUNCT
dti-2638	52	9	to	to	PART
dti-2638	52	10	be	be	AUX
dti-2638	52	11	important	important	ADJ
dti-2638	52	12	for	for	ADP
dti-2638	52	13	virulence	virulence	NOUN
dti-2638	52	14	expression	expression	NOUN
dti-2638	52	15	of	of	ADP
dti-2638	52	16	this	this	DET
dti-2638	52	17	pathogen	pathogen	NOUN
dti-2638	52	18	,	,	PUNCT
dti-2638	52	19	and	and	CCONJ
dti-2638	52	20	thus	thus	ADV
dti-2638	52	21	can	can	AUX
dti-2638	52	22	be	be	AUX
dti-2638	52	23	a	a	DET
dti-2638	52	24	plausible	plausible	ADJ
dti-2638	52	25	target	target	NOUN
dti-2638	52	26	for	for	ADP
dti-2638	52	27	novel	novel	ADJ
dti-2638	52	28	anti	anti	ADJ
dti-2638	52	29	-	-	ADJ
dti-2638	52	30	virulence	virulence	ADJ
dti-2638	52	31	agents	agent	NOUN
dti-2638	52	32	.	.	PUNCT
dti-2638	53	1	molecules	molecule	NOUN
dti-2638	53	2	capable	capable	ADJ
dti-2638	53	3	of	of	ADP
dti-2638	53	4	inhibiting	inhibit	VERB
dti-2638	53	5	nor	nor	CCONJ
dti-2638	53	6	can	can	AUX
dti-2638	53	7	be	be	AUX
dti-2638	53	8	expected	expect	VERB
dti-2638	53	9	to	to	PART
dti-2638	53	10	compromise	compromise	VERB
dti-2638	53	11	the	the	DET
dti-2638	53	12	pathogen	pathogen	NOUN
dti-2638	53	13	’s	’s	PART
dti-2638	53	14	ability	ability	NOUN
dti-2638	53	15	to	to	PART
dti-2638	53	16	detoxify	detoxify	VERB
dti-2638	53	17	no	no	PRON
dti-2638	53	18	,	,	PUNCT
dti-2638	53	19	not	not	PART
dti-2638	53	20	allowing	allow	VERB
dti-2638	53	21	its	its	PRON
dti-2638	53	22	virulence	virulence	NOUN
dti-2638	53	23	traits	trait	NOUN
dti-2638	53	24	(	(	PUNCT
dti-2638	53	25	e.g.	e.g.	ADV
dti-2638	53	26	biofilm	biofilm	NOUN
dti-2638	53	27	formation	formation	NOUN
dti-2638	53	28	,	,	PUNCT
dti-2638	53	29	as	as	SCONJ
dti-2638	53	30	no	no	PRON
dti-2638	53	31	has	have	AUX
dti-2638	53	32	been	be	AUX
dti-2638	53	33	indicated	indicate	VERB
dti-2638	53	34	to	to	PART
dti-2638	53	35	act	act	VERB
dti-2638	53	36	as	as	ADP
dti-2638	53	37	a	a	DET
dti-2638	53	38	biofilm	biofilm	NOUN
dti-2638	53	39	-	-	PUNCT
dti-2638	53	40	dispersal	dispersal	NOUN
dti-2638	53	41	signal	signal	NOUN
dti-2638	53	42	)	)	PUNCT
dti-2638	53	43	to	to	PART
dti-2638	53	44	be	be	AUX
dti-2638	53	45	expressed	express	VERB
dti-2638	53	46	fully	fully	ADV
dti-2638	53	47	(	(	PUNCT
dti-2638	53	48	30	30	NUM
dti-2638	53	49	)	)	PUNCT
dti-2638	53	50	.	.	PUNCT
dti-2638	54	1	the	the	DET
dti-2638	54	2	test	test	NOUN
dti-2638	54	3	molecules	molecule	NOUN
dti-2638	54	4	capable	capable	ADJ
dti-2638	54	5	of	of	ADP
dti-2638	54	6	inhibiting	inhibit	VERB
dti-2638	54	7	nor	nor	CCONJ
dti-2638	54	8	may	may	AUX
dti-2638	54	9	emerge	emerge	VERB
dti-2638	54	10	as	as	ADP
dti-2638	54	11	novel	novel	ADJ
dti-2638	54	12	anti	anti	ADJ
dti-2638	54	13	-	-	ADJ
dti-2638	54	14	biofilm	biofilm	ADJ
dti-2638	54	15	agents	agent	NOUN
dti-2638	54	16	not	not	PART
dti-2638	54	17	only	only	ADV
dti-2638	54	18	against	against	ADP
dti-2638	54	19	p.	p.	NOUN
dti-2638	54	20	aeruginosa	aeruginosa	NOUN
dti-2638	54	21	but	but	CCONJ
dti-2638	54	22	against	against	ADP
dti-2638	54	23	multiple	multiple	ADJ
dti-2638	54	24	pathogens	pathogen	NOUN
dti-2638	54	25	as	as	ADP
dti-2638	54	26	no	no	PRON
dti-2638	54	27	is	be	AUX
dti-2638	54	28	reported	report	VERB
dti-2638	54	29	to	to	PART
dti-2638	54	30	be	be	AUX
dti-2638	54	31	perceived	perceive	VERB
dti-2638	54	32	as	as	ADP
dti-2638	54	33	a	a	DET
dti-2638	54	34	dispersal	dispersal	NOUN
dti-2638	54	35	signal	signal	NOUN
dti-2638	54	36	by	by	ADP
dti-2638	54	37	various	various	ADJ
dti-2638	54	38	gram	gram	NOUN
dti-2638	54	39	-	-	PUNCT
dti-2638	54	40	negative	negative	ADJ
dti-2638	54	41	and	and	CCONJ
dti-2638	54	42	gram	gram	NOUN
dti-2638	54	43	-	-	PUNCT
dti-2638	54	44	positive	positive	ADJ
dti-2638	54	45	bacteria	bacteria	NOUN
dti-2638	54	46	(	(	PUNCT
dti-2638	54	47	31	31	NUM
dti-2638	54	48	)	)	PUNCT
dti-2638	54	49	.	.	PUNCT
dti-2638	55	1	thus	thus	ADV
dti-2638	55	2	,	,	PUNCT
dti-2638	55	3	nor	nor	CCONJ
dti-2638	55	4	inhibitors	inhibitor	NOUN
dti-2638	55	5	may	may	AUX
dti-2638	55	6	be	be	AUX
dti-2638	55	7	expected	expect	VERB
dti-2638	55	8	to	to	PART
dti-2638	55	9	have	have	VERB
dti-2638	55	10	a	a	DET
dti-2638	55	11	broad	broad	ADJ
dti-2638	55	12	-	-	PUNCT
dti-2638	55	13	spectrum	spectrum	NOUN
dti-2638	55	14	activity	activity	NOUN
dti-2638	55	15	against	against	ADP
dti-2638	55	16	multiple	multiple	ADJ
dti-2638	55	17	pathogens	pathogen	NOUN
dti-2638	55	18	.	.	PUNCT
dti-2638	56	1	major	major	ADJ
dti-2638	56	2	function	function	NOUN
dti-2638	56	3	of	of	ADP
dti-2638	56	4	nor	nor	CCONJ
dti-2638	56	5	is	be	AUX
dti-2638	56	6	to	to	PART
dti-2638	56	7	detoxify	detoxify	VERB
dti-2638	56	8	no	no	DET
dti-2638	56	9	generated	generate	VERB
dti-2638	56	10	by	by	ADP
dti-2638	56	11	nitrite	nitrite	NOUN
dti-2638	56	12	reductase	reductase	NOUN
dti-2638	56	13	(	(	PUNCT
dti-2638	56	14	nir	nir	NOUN
dti-2638	56	15	)	)	PUNCT
dti-2638	56	16	.	.	PUNCT
dti-2638	57	1	no	no	PRON
dti-2638	57	2	is	be	AUX
dti-2638	57	3	a	a	DET
dti-2638	57	4	toxic	toxic	ADJ
dti-2638	57	5	by	by	ADP
dti-2638	57	6	-	-	PUNCT
dti-2638	57	7	product	product	NOUN
dti-2638	57	8	of	of	ADP
dti-2638	57	9	anaerobic	anaerobic	ADJ
dti-2638	57	10	respiration	respiration	NOUN
dti-2638	57	11	in	in	ADP
dti-2638	57	12	p.	p.	PROPN
dti-2638	57	13	aeruginosa	aeruginosa	PROPN
dti-2638	57	14	.	.	PUNCT
dti-2638	58	1	no	no	PRON
dti-2638	58	2	-	-	PUNCT
dti-2638	58	3	derived	derive	VERB
dti-2638	58	4	nitrosative	nitrosative	ADJ
dti-2638	58	5	species	specie	NOUN
dti-2638	58	6	can	can	AUX
dti-2638	58	7	damage	damage	VERB
dti-2638	58	8	deoxyribonucleic	deoxyribonucleic	ADJ
dti-2638	58	9	acid	acid	NOUN
dti-2638	58	10	(	(	PUNCT
dti-2638	58	11	dna	dna	PROPN
dti-2638	58	12	)	)	PUNCT
dti-2638	58	13	and	and	CCONJ
dti-2638	58	14	compromise	compromise	VERB
dti-2638	58	15	protein	protein	NOUN
dti-2638	58	16	function	function	NOUN
dti-2638	58	17	.	.	PUNCT
dti-2638	59	1	intracellular	intracellular	ADJ
dti-2638	59	2	accumulation	accumulation	NOUN
dti-2638	59	3	of	of	ADP
dti-2638	59	4	no	no	PRON
dti-2638	59	5	is	be	AUX
dti-2638	59	6	likely	likely	ADJ
dti-2638	59	7	to	to	PART
dti-2638	59	8	be	be	AUX
dti-2638	59	9	lethal	lethal	ADJ
dti-2638	59	10	for	for	ADP
dti-2638	59	11	the	the	DET
dti-2638	59	12	pathogen	pathogen	NOUN
dti-2638	59	13	(	(	PUNCT
dti-2638	59	14	32	32	NUM
dti-2638	59	15	)	)	PUNCT
dti-2638	59	16	.	.	PUNCT
dti-2638	60	1	it	it	PRON
dti-2638	60	2	can	can	AUX
dti-2638	60	3	be	be	AUX
dti-2638	60	4	logically	logically	ADV
dti-2638	60	5	anticipated	anticipate	VERB
dti-2638	60	6	that	that	SCONJ
dti-2638	60	7	p.	p.	PROPN
dti-2638	60	8	aeruginosa	aeruginosa	PROPN
dti-2638	60	9	’s	’s	PART
dti-2638	60	10	ability	ability	NOUN
dti-2638	60	11	to	to	PART
dti-2638	60	12	detoxify	detoxify	VERB
dti-2638	60	13	no	no	PRON
dti-2638	60	14	will	will	AUX
dti-2638	60	15	be	be	AUX
dti-2638	60	16	compromised	compromise	VERB
dti-2638	60	17	under	under	ADP
dti-2638	60	18	the	the	DET
dti-2638	60	19	influence	influence	NOUN
dti-2638	60	20	of	of	ADP
dti-2638	60	21	a	a	DET
dti-2638	60	22	potent	potent	NOUN
dti-2638	60	23	nor	nor	CCONJ
dti-2638	60	24	inhibitor	inhibitor	NOUN
dti-2638	60	25	.	.	PUNCT
dti-2638	61	1	since	since	SCONJ
dti-2638	61	2	no	no	PRON
dti-2638	61	3	seems	seem	VERB
dti-2638	61	4	to	to	PART
dti-2638	61	5	have	have	VERB
dti-2638	61	6	a	a	DET
dti-2638	61	7	broad	broad	ADJ
dti-2638	61	8	spectrum	spectrum	NOUN
dti-2638	61	9	anti	anti	ADJ
dti-2638	61	10	-	-	ADJ
dti-2638	61	11	biofilm	biofilm	ADJ
dti-2638	61	12	effect	effect	NOUN
dti-2638	61	13	,	,	PUNCT
dti-2638	61	14	nor	nor	CCONJ
dti-2638	61	15	activity	activity	NOUN
dti-2638	61	16	is	be	AUX
dti-2638	61	17	essential	essential	ADJ
dti-2638	61	18	for	for	ADP
dti-2638	61	19	effective	effective	ADJ
dti-2638	61	20	biofilm	biofilm	NOUN
dti-2638	61	21	formation	formation	NOUN
dti-2638	61	22	by	by	ADP
dti-2638	61	23	the	the	DET
dti-2638	61	24	pathogens	pathogen	NOUN
dti-2638	61	25	.	.	PUNCT
dti-2638	62	1	nor	nor	CCONJ
dti-2638	62	2	activity	activity	NOUN
dti-2638	62	3	and	and	CCONJ
dti-2638	62	4	no	no	DET
dti-2638	62	5	concentration	concentration	NOUN
dti-2638	62	6	can	can	AUX
dti-2638	62	7	modulate	modulate	VERB
dti-2638	62	8	cellular	cellular	ADJ
dti-2638	62	9	levels	level	NOUN
dti-2638	62	10	of	of	ADP
dti-2638	62	11	cyclic	cyclic	PROPN
dti-2638	62	12	di	di	PROPN
dti-2638	62	13	-	-	PUNCT
dti-2638	62	14	gmp	gmp	PROPN
dti-2638	62	15	,	,	PUNCT
dti-2638	62	16	which	which	PRON
dti-2638	62	17	is	be	AUX
dti-2638	62	18	a	a	DET
dti-2638	62	19	secondary	secondary	ADJ
dti-2638	62	20	messenger	messenger	NOUN
dti-2638	62	21	molecule	molecule	NOUN
dti-2638	62	22	recognized	recognize	VERB
dti-2638	62	23	as	as	ADP
dti-2638	62	24	a	a	DET
dti-2638	62	25	key	key	ADJ
dti-2638	62	26	bacterial	bacterial	ADJ
dti-2638	62	27	regulator	regulator	NOUN
dti-2638	62	28	of	of	ADP
dti-2638	62	29	multiple	multiple	ADJ
dti-2638	62	30	processes	process	NOUN
dti-2638	62	31	such	such	ADJ
dti-2638	62	32	as	as	ADP
dti-2638	62	33	virulence	virulence	NOUN
dti-2638	62	34	,	,	PUNCT
dti-2638	62	35	differentiation	differentiation	NOUN
dti-2638	62	36	,	,	PUNCT
dti-2638	62	37	and	and	CCONJ
dti-2638	62	38	biofilm	biofilm	NOUN
dti-2638	62	39	formation	formation	NOUN
dti-2638	62	40	(	(	PUNCT
dti-2638	62	41	33	33	NUM
dti-2638	62	42	)	)	PUNCT
dti-2638	62	43	.	.	PUNCT
dti-2638	63	1	in	in	ADP
dti-2638	63	2	mammalian	mammalian	ADJ
dti-2638	63	3	pathogens	pathogen	NOUN
dti-2638	63	4	,	,	PUNCT
dti-2638	63	5	the	the	DET
dti-2638	63	6	host	host	NOUN
dti-2638	63	7	’s	’s	PART
dti-2638	63	8	macrophages	macrophage	NOUN
dti-2638	63	9	are	be	AUX
dti-2638	63	10	a	a	DET
dti-2638	63	11	likely	likely	ADJ
dti-2638	63	12	source	source	NOUN
dti-2638	63	13	of	of	ADP
dti-2638	63	14	no	no	NOUN
dti-2638	63	15	.	.	PUNCT
dti-2638	63	16	nor	nor	CCONJ
dti-2638	63	17	expressed	express	VERB
dti-2638	63	18	by	by	ADP
dti-2638	63	19	the	the	DET
dti-2638	63	20	pathogen	pathogen	NOUN
dti-2638	63	21	provides	provide	VERB
dti-2638	63	22	protection	protection	NOUN
dti-2638	63	23	against	against	ADP
dti-2638	63	24	the	the	DET
dti-2638	63	25	host	host	NOUN
dti-2638	63	26	defence	defence	NOUN
dti-2638	63	27	mechanism	mechanism	NOUN
dti-2638	63	28	.	.	PUNCT
dti-2638	64	1	since	since	SCONJ
dti-2638	64	2	nor	nor	CCONJ
dti-2638	64	3	activity	activity	NOUN
dti-2638	64	4	is	be	AUX
dti-2638	64	5	known	know	VERB
dti-2638	64	6	to	to	PART
dti-2638	64	7	be	be	AUX
dti-2638	64	8	important	important	ADJ
dti-2638	64	9	in	in	ADP
dti-2638	64	10	multiple	multiple	ADJ
dti-2638	64	11	pathogenic	pathogenic	ADJ
dti-2638	64	12	bacteria	bacteria	NOUN
dti-2638	64	13	(	(	PUNCT
dti-2638	64	14	e.g.	e.g.	ADV
dti-2638	64	15	p.	p.	NOUN
dti-2638	64	16	aeruginosa	aeruginosa	PROPN
dti-2638	64	17	,	,	PUNCT
dti-2638	64	18	staphylococcus	staphylococcus	NOUN
dti-2638	64	19	aureus	aureus	NOUN
dti-2638	64	20	,	,	PUNCT
dti-2638	64	21	serratia	serratia	NOUN
dti-2638	64	22	marcescens	marcescen	NOUN
dti-2638	64	23	)	)	PUNCT
dti-2638	64	24	for	for	ADP
dti-2638	64	25	biofilm	biofilm	NOUN
dti-2638	64	26	formation	formation	NOUN
dti-2638	64	27	,	,	PUNCT
dti-2638	64	28	virulence	virulence	NOUN
dti-2638	64	29	expression	expression	NOUN
dti-2638	64	30	,	,	PUNCT
dti-2638	64	31	combating	combat	VERB
dti-2638	64	32	nitrosative	nitrosative	ADJ
dti-2638	64	33	stress	stress	NOUN
dti-2638	64	34	,	,	PUNCT
dti-2638	64	35	and	and	CCONJ
dti-2638	64	36	evading	evade	VERB
dti-2638	64	37	hose	hose	NOUN
dti-2638	64	38	defence	defence	NOUN
dti-2638	64	39	,	,	PUNCT
dti-2638	64	40	nor	nor	CCONJ
dti-2638	64	41	seems	seem	VERB
dti-2638	64	42	to	to	PART
dti-2638	64	43	be	be	AUX
dti-2638	64	44	an	an	DET
dti-2638	64	45	important	important	ADJ
dti-2638	64	46	target	target	NOUN
dti-2638	64	47	for	for	ADP
dti-2638	64	48	novel	novel	ADJ
dti-2638	64	49	anti	anti	ADJ
dti-2638	64	50	-	-	ADJ
dti-2638	64	51	pathogenic	pathogenic	ADJ
dti-2638	64	52	agents	agent	NOUN
dti-2638	64	53	.	.	PUNCT
dti-2638	65	1	any	any	DET
dti-2638	65	2	molecule	molecule	NOUN
dti-2638	65	3	capable	capable	ADJ
dti-2638	65	4	of	of	ADP
dti-2638	65	5	interfering	interfere	VERB
dti-2638	65	6	with	with	ADP
dti-2638	65	7	bacterial	bacterial	ADJ
dti-2638	65	8	nor	nor	CCONJ
dti-2638	65	9	activity	activity	NOUN
dti-2638	65	10	is	be	AUX
dti-2638	65	11	likely	likely	ADJ
dti-2638	65	12	to	to	PART
dti-2638	65	13	be	be	AUX
dti-2638	65	14	an	an	DET
dti-2638	65	15	effective	effective	ADJ
dti-2638	65	16	anti	anti	ADJ
dti-2638	65	17	-	-	ADJ
dti-2638	65	18	pathogenic	pathogenic	ADJ
dti-2638	65	19	agent	agent	NOUN
dti-2638	65	20	,	,	PUNCT
dti-2638	65	21	since	since	SCONJ
dti-2638	65	22	bacterial	bacterial	ADJ
dti-2638	65	23	populations	population	NOUN
dti-2638	65	24	require	require	VERB
dti-2638	65	25	nor	nor	CCONJ
dti-2638	65	26	for	for	ADP
dti-2638	65	27	various	various	ADJ
dti-2638	65	28	purposes	purpose	NOUN
dti-2638	65	29	including	include	VERB
dti-2638	65	30	detoxification	detoxification	NOUN
dti-2638	65	31	and	and	CCONJ
dti-2638	65	32	evasion	evasion	NOUN
dti-2638	65	33	of	of	ADP
dti-2638	65	34	host	host	NOUN
dti-2638	65	35	defences	defence	NOUN
dti-2638	65	36	(	(	PUNCT
dti-2638	65	37	34	34	NUM
dti-2638	65	38	)	)	PUNCT
dti-2638	65	39	.	.	PUNCT
dti-2638	66	1	a	a	DET
dti-2638	66	2	potential	potential	NOUN
dti-2638	66	3	nor	nor	CCONJ
dti-2638	66	4	inhibitor	inhibitor	NOUN
dti-2638	66	5	besides	besides	SCONJ
dti-2638	66	6	troubling	trouble	VERB
dti-2638	66	7	the	the	DET
dti-2638	66	8	pathogen	pathogen	NOUN
dti-2638	66	9	directly	directly	ADV
dti-2638	66	10	may	may	AUX
dti-2638	66	11	also	also	ADV
dti-2638	66	12	boost	boost	VERB
dti-2638	66	13	its	its	PRON
dti-2638	66	14	clearance	clearance	NOUN
dti-2638	66	15	by	by	ADP
dti-2638	66	16	the	the	DET
dti-2638	66	17	host	host	NOUN
dti-2638	66	18	macrophages	macrophage	NOUN
dti-2638	66	19	.	.	PUNCT
dti-2638	67	1	proteins	protein	NOUN
dti-2638	67	2	such	such	ADJ
dti-2638	67	3	as	as	ADP
dti-2638	67	4	lasr	lasr	PROPN
dti-2638	67	5	and	and	CCONJ
dti-2638	67	6	nor	nor	CCONJ
dti-2638	67	7	important	important	ADJ
dti-2638	67	8	to	to	ADP
dti-2638	67	9	the	the	DET
dti-2638	67	10	pathogens	pathogen	NOUN
dti-2638	67	11	and	and	CCONJ
dti-2638	67	12	whose	whose	DET
dti-2638	67	13	structure	structure	NOUN
dti-2638	67	14	is	be	AUX
dti-2638	67	15	known	know	VERB
dti-2638	67	16	can	can	AUX
dti-2638	67	17	be	be	AUX
dti-2638	67	18	useful	useful	ADJ
dti-2638	67	19	starting	starting	NOUN
dti-2638	67	20	point	point	NOUN
dti-2638	67	21	for	for	ADP
dti-2638	67	22	a	a	DET
dti-2638	67	23	drug	drug	NOUN
dti-2638	67	24	discovery	discovery	NOUN
dti-2638	67	25	programme	programme	NOUN
dti-2638	67	26	.	.	PUNCT
dti-2638	68	1	in	in	ADP
dti-2638	68	2	silico	silico	NOUN
dti-2638	68	3	virtual	virtual	ADJ
dti-2638	68	4	screening	screening	NOUN
dti-2638	68	5	tools	tool	NOUN
dti-2638	68	6	can	can	AUX
dti-2638	68	7	be	be	AUX
dti-2638	68	8	used	use	VERB
dti-2638	68	9	to	to	PART
dti-2638	68	10	screen	screen	VERB
dti-2638	68	11	large	large	ADJ
dti-2638	68	12	chemical	chemical	NOUN
dti-2638	68	13	libraries	library	NOUN
dti-2638	68	14	gajera	gajera	PROPN
dti-2638	68	15	et	et	PROPN
dti-2638	68	16	al	al	PROPN
dti-2638	68	17	drug	drug	PROPN
dti-2638	68	18	target	target	NOUN
dti-2638	68	19	insights	insight	NOUN
dti-2638	68	20	2023	2023	NUM
dti-2638	68	21	;	;	PUNCT
dti-2638	68	22	17	17	NUM
dti-2638	68	23	:	:	SYM
dti-2638	68	24	103	103	NUM
dti-2638	68	25	©	©	PROPN
dti-2638	68	26	2023	2023	NUM
dti-2638	68	27	the	the	DET
dti-2638	68	28	authors	author	NOUN
dti-2638	68	29	.	.	PUNCT
dti-2638	69	1	published	publish	VERB
dti-2638	69	2	by	by	ADP
dti-2638	69	3	aboutscience	aboutscience	NOUN
dti-2638	69	4	www.aboutscience.eu	www.aboutscience.eu	NOUN
dti-2638	69	5	to	to	PART
dti-2638	69	6	predict	predict	VERB
dti-2638	69	7	inhibitors	inhibitor	NOUN
dti-2638	69	8	of	of	ADP
dti-2638	69	9	the	the	DET
dti-2638	69	10	target	target	NOUN
dti-2638	69	11	proteins	protein	NOUN
dti-2638	69	12	.	.	PUNCT
dti-2638	70	1	in	in	ADP
dti-2638	70	2	the	the	DET
dti-2638	70	3	recent	recent	ADJ
dti-2638	70	4	past	past	NOUN
dti-2638	70	5	,	,	PUNCT
dti-2638	70	6	quite	quite	DET
dti-2638	70	7	a	a	DET
dti-2638	70	8	few	few	ADJ
dti-2638	70	9	potent	potent	ADJ
dti-2638	70	10	anti	anti	ADJ
dti-2638	70	11	-	-	ADJ
dti-2638	70	12	pathogenic	pathogenic	ADJ
dti-2638	70	13	compounds	compound	NOUN
dti-2638	70	14	have	have	AUX
dti-2638	70	15	been	be	AUX
dti-2638	70	16	identified	identify	VERB
dti-2638	70	17	using	use	VERB
dti-2638	70	18	this	this	DET
dti-2638	70	19	approach	approach	NOUN
dti-2638	70	20	.	.	PUNCT
dti-2638	71	1	for	for	ADP
dti-2638	71	2	example	example	NOUN
dti-2638	71	3	,	,	PUNCT
dti-2638	71	4	one	one	NUM
dti-2638	71	5	such	such	ADJ
dti-2638	71	6	virtual	virtual	ADJ
dti-2638	71	7	screening	screening	NOUN
dti-2638	71	8	study	study	NOUN
dti-2638	71	9	by	by	ADP
dti-2638	71	10	abelyan	abelyan	PROPN
dti-2638	71	11	et	et	PROPN
dti-2638	71	12	al	al	PROPN
dti-2638	71	13	(	(	PUNCT
dti-2638	71	14	35	35	NUM
dti-2638	71	15	)	)	PUNCT
dti-2638	71	16	identified	identify	VERB
dti-2638	71	17	benzamides	benzamide	NOUN
dti-2638	71	18	,	,	PUNCT
dti-2638	71	19	synthetic	synthetic	ADJ
dti-2638	71	20	derivatives	derivative	NOUN
dti-2638	71	21	of	of	ADP
dti-2638	71	22	flavones	flavone	NOUN
dti-2638	71	23	,	,	PUNCT
dti-2638	71	24	as	as	ADP
dti-2638	71	25	potential	potential	ADJ
dti-2638	71	26	inhibitors	inhibitor	NOUN
dti-2638	71	27	of	of	ADP
dti-2638	71	28	lasr	lasr	PROPN
dti-2638	71	29	.	.	PUNCT
dti-2638	72	1	another	another	PRON
dti-2638	72	2	in	in	ADP
dti-2638	72	3	silico	silico	NOUN
dti-2638	72	4	effort	effort	NOUN
dti-2638	72	5	by	by	ADP
dti-2638	72	6	narayanaswamy	narayanaswamy	NOUN
dti-2638	72	7	et	et	PROPN
dti-2638	72	8	al	al	PROPN
dti-2638	72	9	(	(	PUNCT
dti-2638	72	10	36	36	NUM
dti-2638	72	11	)	)	PUNCT
dti-2638	72	12	identified	identify	VERB
dti-2638	72	13	potent	potent	ADJ
dti-2638	72	14	inhibitors	inhibitor	NOUN
dti-2638	72	15	of	of	ADP
dti-2638	72	16	enzymes	enzyme	NOUN
dti-2638	72	17	involved	involve	VERB
dti-2638	72	18	in	in	ADP
dti-2638	72	19	nitrogen	nitrogen	NOUN
dti-2638	72	20	metabolism	metabolism	NOUN
dti-2638	72	21	in	in	ADP
dti-2638	72	22	various	various	ADJ
dti-2638	72	23	bacteria	bacteria	NOUN
dti-2638	72	24	including	include	VERB
dti-2638	72	25	p.	p.	NOUN
dti-2638	72	26	aeruginosa	aeruginosa	PROPN
dti-2638	72	27	,	,	PUNCT
dti-2638	72	28	nitrous	nitrous	ADJ
dti-2638	72	29	oxide	oxide	NOUN
dti-2638	72	30	reductase	reductase	NOUN
dti-2638	72	31	(	(	PUNCT
dti-2638	72	32	n2or	n2or	NUM
dti-2638	72	33	)	)	PUNCT
dti-2638	72	34	,	,	PUNCT
dti-2638	72	35	and	and	CCONJ
dti-2638	72	36	nir	nir	NOUN
dti-2638	72	37	,	,	PUNCT
dti-2638	72	38	from	from	ADP
dti-2638	72	39	among	among	ADP
dti-2638	72	40	a	a	DET
dti-2638	72	41	library	library	NOUN
dti-2638	72	42	of	of	ADP
dti-2638	72	43	synthetic	synthetic	ADJ
dti-2638	72	44	and	and	CCONJ
dti-2638	72	45	natural	natural	ADJ
dti-2638	72	46	compounds	compound	NOUN
dti-2638	72	47	.	.	PUNCT
dti-2638	73	1	this	this	DET
dti-2638	73	2	study	study	NOUN
dti-2638	73	3	aimed	aim	VERB
dti-2638	73	4	at	at	ADP
dti-2638	73	5	screening	screen	VERB
dti-2638	73	6	96	96	NUM
dti-2638	73	7	compounds	compound	NOUN
dti-2638	73	8	identified	identify	VERB
dti-2638	73	9	through	through	ADP
dti-2638	73	10	a	a	DET
dti-2638	73	11	virtual	virtual	ADJ
dti-2638	73	12	screen	screen	NOUN
dti-2638	73	13	as	as	ADP
dti-2638	73	14	potential	potential	ADJ
dti-2638	73	15	lasr	lasr	PROPN
dti-2638	73	16	inhibitors	inhibitor	NOUN
dti-2638	73	17	,	,	PUNCT
dti-2638	73	18	and	and	CCONJ
dti-2638	73	19	85	85	NUM
dti-2638	73	20	compounds	compound	NOUN
dti-2638	73	21	predicted	predict	VERB
dti-2638	73	22	to	to	PART
dti-2638	73	23	be	be	AUX
dti-2638	73	24	nor	nor	CCONJ
dti-2638	73	25	inhibitors	inhibitor	NOUN
dti-2638	73	26	in	in	ADP
dti-2638	73	27	silico	silico	NOUN
dti-2638	73	28	for	for	ADP
dti-2638	73	29	their	their	PRON
dti-2638	73	30	possible	possible	ADJ
dti-2638	73	31	anti	anti	ADJ
dti-2638	73	32	-	-	ADJ
dti-2638	73	33	virulence	virulence	ADJ
dti-2638	73	34	activity	activity	NOUN
dti-2638	73	35	against	against	ADP
dti-2638	73	36	p.	p.	NOUN
dti-2638	73	37	aeruginosa	aeruginosa	PROPN
dti-2638	73	38	in	in	ADP
dti-2638	73	39	the	the	DET
dti-2638	73	40	model	model	NOUN
dti-2638	73	41	host	host	NOUN
dti-2638	73	42	caenorhabditis	caenorhabditis	PROPN
dti-2638	73	43	elegans	elegans	PROPN
dti-2638	73	44	.	.	PUNCT
dti-2638	74	1	any	any	DET
dti-2638	74	2	such	such	ADJ
dti-2638	74	3	potent	potent	NOUN
dti-2638	74	4	nor	nor	CCONJ
dti-2638	74	5	or	or	CCONJ
dti-2638	74	6	lasr	lasr	NOUN
dti-2638	74	7	inhibitors	inhibitor	NOUN
dti-2638	74	8	identified	identify	VERB
dti-2638	74	9	through	through	ADP
dti-2638	74	10	this	this	DET
dti-2638	74	11	study	study	NOUN
dti-2638	74	12	may	may	AUX
dti-2638	74	13	prove	prove	VERB
dti-2638	74	14	to	to	PART
dti-2638	74	15	be	be	AUX
dti-2638	74	16	useful	useful	ADJ
dti-2638	74	17	lead(s	lead(s	NOUN
dti-2638	74	18	)	)	PUNCT
dti-2638	74	19	for	for	ADP
dti-2638	74	20	novel	novel	ADJ
dti-2638	74	21	anti	anti	ADJ
dti-2638	74	22	-	-	ADJ
dti-2638	74	23	pathogenic	pathogenic	ADJ
dti-2638	74	24	drug	drug	NOUN
dti-2638	74	25	development	development	NOUN
dti-2638	74	26	.	.	PUNCT
dti-2638	75	1	they	they	PRON
dti-2638	75	2	can	can	AUX
dti-2638	75	3	be	be	AUX
dti-2638	75	4	useful	useful	ADJ
dti-2638	75	5	either	either	CCONJ
dti-2638	75	6	as	as	ADP
dti-2638	75	7	standalone	standalone	NOUN
dti-2638	75	8	therapy	therapy	NOUN
dti-2638	75	9	or	or	CCONJ
dti-2638	75	10	in	in	ADP
dti-2638	75	11	combination	combination	NOUN
dti-2638	75	12	with	with	ADP
dti-2638	75	13	conventional	conventional	ADJ
dti-2638	75	14	antibiotics	antibiotic	NOUN
dti-2638	75	15	.	.	PUNCT
dti-2638	76	1	methods	method	NOUN
dti-2638	76	2	virtual	virtual	ADJ
dti-2638	76	3	screening	screen	VERB
dti-2638	76	4	the	the	DET
dti-2638	76	5	virtual	virtual	ADJ
dti-2638	76	6	screening	screening	NOUN
dti-2638	76	7	from	from	ADP
dti-2638	76	8	a	a	DET
dti-2638	76	9	library	library	NOUN
dti-2638	76	10	of	of	ADP
dti-2638	76	11	approximately	approximately	ADV
dti-2638	76	12	3	3	NUM
dti-2638	76	13	million	million	NUM
dti-2638	76	14	compounds	compound	NOUN
dti-2638	76	15	was	be	AUX
dti-2638	76	16	conducted	conduct	VERB
dti-2638	76	17	using	use	VERB
dti-2638	76	18	atomnet	atomnet	ADJ
dti-2638	76	19	®	®	NOUN
dti-2638	76	20	screening	screen	VERB
dti-2638	76	21	platform	platform	NOUN
dti-2638	76	22	(	(	PUNCT
dti-2638	76	23	37	37	NUM
dti-2638	76	24	)	)	PUNCT
dti-2638	76	25	.	.	PUNCT
dti-2638	77	1	atomnet	atomnet	PROPN
dti-2638	77	2	®	®	NOUN
dti-2638	77	3	is	be	AUX
dti-2638	77	4	a	a	DET
dti-2638	77	5	proprietary	proprietary	ADJ
dti-2638	77	6	deep	deep	ADJ
dti-2638	77	7	learning	learn	VERB
dti-2638	77	8	neural	neural	ADJ
dti-2638	77	9	network	network	NOUN
dti-2638	77	10	useful	useful	ADJ
dti-2638	77	11	for	for	ADP
dti-2638	77	12	structure	structure	NOUN
dti-2638	77	13	-	-	PUNCT
dti-2638	77	14	based	base	VERB
dti-2638	77	15	drug	drug	NOUN
dti-2638	77	16	design	design	NOUN
dti-2638	77	17	and	and	CCONJ
dti-2638	77	18	discovery	discovery	NOUN
dti-2638	77	19	through	through	ADP
dti-2638	77	20	its	its	PRON
dti-2638	77	21	small	small	ADJ
dti-2638	77	22	-	-	PUNCT
dti-2638	77	23	molecule	molecule	NOUN
dti-2638	77	24	binding	bind	VERB
dti-2638	77	25	affinity	affinity	NOUN
dti-2638	77	26	prediction	prediction	NOUN
dti-2638	77	27	capacity	capacity	NOUN
dti-2638	77	28	.	.	PUNCT
dti-2638	78	1	screening	screen	VERB
dti-2638	78	2	for	for	ADP
dti-2638	78	3	lasr	lasr	PROPN
dti-2638	78	4	binding	bind	VERB
dti-2638	78	5	ligands	ligand	NOUN
dti-2638	78	6	there	there	PRON
dti-2638	78	7	are	be	VERB
dti-2638	78	8	a	a	DET
dti-2638	78	9	number	number	NOUN
dti-2638	78	10	of	of	ADP
dti-2638	78	11	available	available	ADJ
dti-2638	78	12	crystal	crystal	NOUN
dti-2638	78	13	structures	structure	NOUN
dti-2638	78	14	of	of	ADP
dti-2638	78	15	lasr	lasr	PROPN
dti-2638	78	16	in	in	ADP
dti-2638	78	17	complex	complex	NOUN
dti-2638	78	18	with	with	ADP
dti-2638	78	19	small	small	ADJ
dti-2638	78	20	molecules	molecule	NOUN
dti-2638	78	21	,	,	PUNCT
dti-2638	78	22	including	include	VERB
dti-2638	78	23	the	the	DET
dti-2638	78	24	endogenous	endogenous	ADJ
dti-2638	78	25	ligand	ligand	NOUN
dti-2638	78	26	and	and	CCONJ
dti-2638	78	27	other	other	ADJ
dti-2638	78	28	agonists	agonist	NOUN
dti-2638	78	29	.	.	PUNCT
dti-2638	79	1	although	although	SCONJ
dti-2638	79	2	discovery	discovery	NOUN
dti-2638	79	3	of	of	ADP
dti-2638	79	4	a	a	DET
dti-2638	79	5	potent	potent	ADJ
dti-2638	79	6	antagonist	antagonist	NOUN
dti-2638	79	7	is	be	AUX
dti-2638	79	8	preferable	preferable	ADJ
dti-2638	79	9	,	,	PUNCT
dti-2638	79	10	the	the	DET
dti-2638	79	11	virtual	virtual	ADJ
dti-2638	79	12	screen	screen	NOUN
dti-2638	79	13	attempted	attempt	VERB
dti-2638	79	14	to	to	PART
dti-2638	79	15	find	find	VERB
dti-2638	79	16	novel	novel	ADJ
dti-2638	79	17	chemical	chemical	NOUN
dti-2638	79	18	matter	matter	NOUN
dti-2638	79	19	that	that	PRON
dti-2638	79	20	binds	bind	VERB
dti-2638	79	21	at	at	ADP
dti-2638	79	22	the	the	DET
dti-2638	79	23	desired	desire	VERB
dti-2638	79	24	site	site	NOUN
dti-2638	79	25	and	and	CCONJ
dti-2638	79	26	the	the	DET
dti-2638	79	27	mode	mode	NOUN
dti-2638	79	28	of	of	ADP
dti-2638	79	29	binding	bind	VERB
dti-2638	79	30	may	may	AUX
dti-2638	79	31	be	be	AUX
dti-2638	79	32	analysed	analyse	VERB
dti-2638	79	33	later	later	ADV
dti-2638	79	34	.	.	PUNCT
dti-2638	80	1	all	all	PRON
dti-2638	80	2	of	of	ADP
dti-2638	80	3	the	the	DET
dti-2638	80	4	available	available	ADJ
dti-2638	80	5	crystal	crystal	NOUN
dti-2638	80	6	structures	structure	NOUN
dti-2638	80	7	were	be	AUX
dti-2638	80	8	considered	consider	VERB
dti-2638	80	9	as	as	ADP
dti-2638	80	10	receptor	receptor	NOUN
dti-2638	80	11	templates	template	NOUN
dti-2638	80	12	for	for	ADP
dti-2638	80	13	virtual	virtual	ADJ
dti-2638	80	14	screening	screening	NOUN
dti-2638	80	15	.	.	PUNCT
dti-2638	81	1	the	the	DET
dti-2638	81	2	highest	high	ADJ
dti-2638	81	3	resolution	resolution	NOUN
dti-2638	81	4	structure	structure	NOUN
dti-2638	81	5	,	,	PUNCT
dti-2638	81	6	pdb	pdb	PROPN
dti-2638	81	7	3ix3	3ix3	NUM
dti-2638	81	8	,	,	PUNCT
dti-2638	81	9	chosen	choose	VERB
dti-2638	81	10	as	as	ADP
dti-2638	81	11	the	the	DET
dti-2638	81	12	ligand	ligand	ADJ
dti-2638	81	13	binding	bind	VERB
dti-2638	81	14	pocket	pocket	NOUN
dti-2638	81	15	is	be	AUX
dti-2638	81	16	deep	deep	ADJ
dti-2638	81	17	and	and	CCONJ
dti-2638	81	18	solvent	solvent	NOUN
dti-2638	81	19	excluded	exclude	VERB
dti-2638	81	20	and	and	CCONJ
dti-2638	81	21	appears	appear	VERB
dti-2638	81	22	well	well	ADV
dti-2638	81	23	-	-	PUNCT
dti-2638	81	24	suited	suited	ADJ
dti-2638	81	25	for	for	ADP
dti-2638	81	26	binding	bind	VERB
dti-2638	81	27	small	small	ADJ
dti-2638	81	28	molecules	molecule	NOUN
dti-2638	81	29	(	(	PUNCT
dti-2638	81	30	fig	fig	NOUN
dti-2638	81	31	.	.	PUNCT
dti-2638	81	32	1	1	NUM
dti-2638	81	33	)	)	PUNCT
dti-2638	81	34	.	.	PUNCT
dti-2638	82	1	the	the	DET
dti-2638	82	2	screening	screening	NOUN
dti-2638	82	3	volume	volume	NOUN
dti-2638	82	4	was	be	AUX
dti-2638	82	5	restricted	restrict	VERB
dti-2638	82	6	to	to	ADP
dti-2638	82	7	the	the	DET
dti-2638	82	8	binding	bind	VERB
dti-2638	82	9	pocket	pocket	NOUN
dti-2638	82	10	surrounding	surround	VERB
dti-2638	82	11	the	the	DET
dti-2638	82	12	existing	exist	VERB
dti-2638	82	13	ligand	ligand	NOUN
dti-2638	82	14	.	.	PUNCT
dti-2638	83	1	a	a	DET
dti-2638	83	2	screening	screen	VERB
dti-2638	83	3	library	library	NOUN
dti-2638	83	4	of	of	ADP
dti-2638	83	5	approximately	approximately	ADV
dti-2638	83	6	3	3	NUM
dti-2638	83	7	million	million	NUM
dti-2638	83	8	compounds	compound	NOUN
dti-2638	83	9	was	be	AUX
dti-2638	83	10	exhaustively	exhaustively	ADV
dti-2638	83	11	posesampled	posesample	VERB
dti-2638	83	12	and	and	CCONJ
dti-2638	83	13	scored	score	VERB
dti-2638	83	14	,	,	PUNCT
dti-2638	83	15	followed	follow	VERB
dti-2638	83	16	by	by	ADP
dti-2638	83	17	filtering	filter	VERB
dti-2638	83	18	for	for	ADP
dti-2638	83	19	drug	drug	NOUN
dti-2638	83	20	-	-	PUNCT
dti-2638	83	21	like	like	ADJ
dti-2638	83	22	properties	property	NOUN
dti-2638	83	23	,	,	PUNCT
dti-2638	83	24	and	and	CCONJ
dti-2638	83	25	selection	selection	NOUN
dti-2638	83	26	of	of	ADP
dti-2638	83	27	the	the	DET
dti-2638	83	28	top	top	ADJ
dti-2638	83	29	96	96	NUM
dti-2638	83	30	compounds	compound	NOUN
dti-2638	83	31	for	for	ADP
dti-2638	83	32	ordering	order	VERB
dti-2638	83	33	in	in	ADP
dti-2638	83	34	physical	physical	ADJ
dti-2638	83	35	form	form	NOUN
dti-2638	83	36	.	.	PUNCT
dti-2638	84	1	screening	screen	VERB
dti-2638	84	2	for	for	ADP
dti-2638	84	3	nor	nor	CCONJ
dti-2638	84	4	binding	bind	VERB
dti-2638	84	5	ligands	ligand	NOUN
dti-2638	84	6	the	the	DET
dti-2638	84	7	structure	structure	NOUN
dti-2638	84	8	of	of	ADP
dti-2638	84	9	p.	p.	NOUN
dti-2638	84	10	aeruginosa	aeruginosa	PROPN
dti-2638	84	11	nor	nor	CCONJ
dti-2638	84	12	bound	bind	VERB
dti-2638	84	13	to	to	ADP
dti-2638	84	14	an	an	DET
dti-2638	84	15	antibody	antibody	NOUN
dti-2638	84	16	fragment	fragment	NOUN
dti-2638	84	17	has	have	AUX
dti-2638	84	18	been	be	AUX
dti-2638	84	19	determined	determine	VERB
dti-2638	84	20	by	by	ADP
dti-2638	84	21	crystallography	crystallography	NOUN
dti-2638	84	22	(	(	PUNCT
dti-2638	84	23	pdbid	pdbid	NOUN
dti-2638	84	24	3o0r	3o0r	NOUN
dti-2638	84	25	)	)	PUNCT
dti-2638	84	26	.	.	PUNCT
dti-2638	85	1	this	this	DET
dti-2638	85	2	structure	structure	NOUN
dti-2638	85	3	reveals	reveal	VERB
dti-2638	85	4	nor	nor	CCONJ
dti-2638	85	5	composed	compose	VERB
dti-2638	85	6	of	of	ADP
dti-2638	85	7	two	two	NUM
dti-2638	85	8	subunits	subunit	NOUN
dti-2638	85	9	:	:	PUNCT
dti-2638	85	10	norb	norb	NOUN
dti-2638	85	11	containing	contain	VERB
dti-2638	85	12	12	12	NUM
dti-2638	85	13	transmembrane	transmembrane	ADJ
dti-2638	85	14	helices	helix	NOUN
dti-2638	85	15	and	and	CCONJ
dti-2638	85	16	norc	norc	VERB
dti-2638	85	17	with	with	ADP
dti-2638	85	18	a	a	DET
dti-2638	85	19	transmembrane	transmembrane	NOUN
dti-2638	85	20	helix	helix	NOUN
dti-2638	85	21	and	and	CCONJ
dti-2638	85	22	hydrophilic	hydrophilic	ADJ
dti-2638	85	23	periplasmic	periplasmic	ADJ
dti-2638	85	24	domain	domain	NOUN
dti-2638	85	25	.	.	PUNCT
dti-2638	86	1	three	three	NUM
dti-2638	86	2	haem	haem	NOUN
dti-2638	86	3	cofactors	cofactor	NOUN
dti-2638	86	4	are	be	AUX
dti-2638	86	5	complexed	complexe	VERB
dti-2638	86	6	in	in	ADP
dti-2638	86	7	nor	nor	CCONJ
dti-2638	86	8	.	.	PUNCT
dti-2638	87	1	two	two	NUM
dti-2638	87	2	haems	haem	NOUN
dti-2638	87	3	are	be	AUX
dti-2638	87	4	deep	deep	ADJ
dti-2638	87	5	in	in	ADP
dti-2638	87	6	the	the	DET
dti-2638	87	7	norb	norb	ADJ
dti-2638	87	8	transmembrane	transmembrane	NOUN
dti-2638	87	9	region	region	NOUN
dti-2638	87	10	,	,	PUNCT
dti-2638	87	11	and	and	CCONJ
dti-2638	87	12	the	the	DET
dti-2638	87	13	third	third	ADJ
dti-2638	87	14	haem	haem	NOUN
dti-2638	87	15	spans	span	VERB
dti-2638	87	16	the	the	DET
dti-2638	87	17	norb	norb	NOUN
dti-2638	87	18	-	-	PUNCT
dti-2638	87	19	norc	norc	NOUN
dti-2638	87	20	interface	interface	NOUN
dti-2638	87	21	.	.	PUNCT
dti-2638	88	1	no	no	DET
dti-2638	88	2	drug	drug	NOUN
dti-2638	88	3	-	-	PUNCT
dti-2638	88	4	like	like	ADJ
dti-2638	88	5	small	small	ADJ
dti-2638	88	6	-	-	PUNCT
dti-2638	88	7	molecule	molecule	NOUN
dti-2638	88	8	inhibitors	inhibitor	NOUN
dti-2638	88	9	have	have	AUX
dti-2638	88	10	been	be	AUX
dti-2638	88	11	reported	report	VERB
dti-2638	88	12	for	for	ADP
dti-2638	88	13	nor	nor	CCONJ
dti-2638	88	14	,	,	PUNCT
dti-2638	88	15	and	and	CCONJ
dti-2638	88	16	no	no	DET
dti-2638	88	17	druggable	druggable	ADJ
dti-2638	88	18	pocket	pocket	NOUN
dti-2638	88	19	is	be	AUX
dti-2638	88	20	obvious	obvious	ADJ
dti-2638	88	21	from	from	ADP
dti-2638	88	22	the	the	DET
dti-2638	88	23	reported	report	VERB
dti-2638	88	24	structure	structure	NOUN
dti-2638	88	25	.	.	PUNCT
dti-2638	89	1	to	to	PART
dti-2638	89	2	identify	identify	VERB
dti-2638	89	3	potential	potential	ADJ
dti-2638	89	4	targetable	targetable	ADJ
dti-2638	89	5	sites	site	NOUN
dti-2638	89	6	,	,	PUNCT
dti-2638	89	7	the	the	DET
dti-2638	89	8	structure	structure	NOUN
dti-2638	89	9	of	of	ADP
dti-2638	89	10	nor	nor	CCONJ
dti-2638	89	11	was	be	AUX
dti-2638	89	12	analysed	analyse	VERB
dti-2638	89	13	by	by	ADP
dti-2638	89	14	fpocket	fpocket	NOUN
dti-2638	89	15	.	.	PUNCT
dti-2638	90	1	this	this	DET
dti-2638	90	2	analysis	analysis	NOUN
dti-2638	90	3	revealed	reveal	VERB
dti-2638	90	4	a	a	DET
dti-2638	90	5	pocket	pocket	NOUN
dti-2638	90	6	at	at	ADP
dti-2638	90	7	the	the	DET
dti-2638	90	8	interface	interface	NOUN
dti-2638	90	9	of	of	ADP
dti-2638	90	10	norb	norb	NOUN
dti-2638	90	11	and	and	CCONJ
dti-2638	90	12	norc	norc	NOUN
dti-2638	90	13	and	and	CCONJ
dti-2638	90	14	near	near	ADP
dti-2638	90	15	one	one	NUM
dti-2638	90	16	of	of	ADP
dti-2638	90	17	the	the	DET
dti-2638	90	18	norb	norb	ADJ
dti-2638	90	19	haem	haem	NOUN
dti-2638	90	20	cofactors	cofactor	NOUN
dti-2638	90	21	.	.	PUNCT
dti-2638	91	1	this	this	DET
dti-2638	91	2	positioning	positioning	NOUN
dti-2638	91	3	suggests	suggest	VERB
dti-2638	91	4	that	that	SCONJ
dti-2638	91	5	small	small	ADJ
dti-2638	91	6	-	-	PUNCT
dti-2638	91	7	molecule	molecule	NOUN
dti-2638	91	8	binding	binding	NOUN
dti-2638	91	9	to	to	ADP
dti-2638	91	10	this	this	DET
dti-2638	91	11	pocket	pocket	NOUN
dti-2638	91	12	may	may	AUX
dti-2638	91	13	disrupt	disrupt	VERB
dti-2638	91	14	norb	norb	NOUN
dti-2638	91	15	-	-	PUNCT
dti-2638	91	16	norc	norc	NOUN
dti-2638	91	17	interactions	interaction	NOUN
dti-2638	91	18	and/or	and/or	CCONJ
dti-2638	91	19	inhibit	inhibit	VERB
dti-2638	91	20	haem	haem	NOUN
dti-2638	91	21	-	-	PUNCT
dti-2638	91	22	mediated	mediate	VERB
dti-2638	91	23	electrochemistry	electrochemistry	NOUN
dti-2638	91	24	.	.	PUNCT
dti-2638	92	1	the	the	DET
dti-2638	92	2	virtual	virtual	ADJ
dti-2638	92	3	screen	screen	NOUN
dti-2638	92	4	therefore	therefore	ADV
dti-2638	92	5	sought	seek	VERB
dti-2638	92	6	to	to	PART
dti-2638	92	7	identify	identify	VERB
dti-2638	92	8	small	small	ADJ
dti-2638	92	9	molecules	molecule	NOUN
dti-2638	92	10	that	that	PRON
dti-2638	92	11	bind	bind	VERB
dti-2638	92	12	to	to	ADP
dti-2638	92	13	this	this	DET
dti-2638	92	14	pocket	pocket	NOUN
dti-2638	92	15	in	in	ADP
dti-2638	92	16	nor	nor	CCONJ
dti-2638	92	17	and	and	CCONJ
dti-2638	92	18	potentially	potentially	ADV
dti-2638	92	19	disrupt	disrupt	VERB
dti-2638	92	20	enzymatic	enzymatic	ADJ
dti-2638	92	21	function	function	NOUN
dti-2638	92	22	.	.	PUNCT
dti-2638	93	1	a	a	DET
dti-2638	93	2	library	library	NOUN
dti-2638	93	3	of	of	ADP
dti-2638	93	4	approximately	approximately	ADV
dti-2638	93	5	3	3	NUM
dti-2638	93	6	million	million	NUM
dti-2638	93	7	compounds	compound	NOUN
dti-2638	93	8	was	be	AUX
dti-2638	93	9	screened	screen	VERB
dti-2638	93	10	for	for	ADP
dti-2638	93	11	identifying	identify	VERB
dti-2638	93	12	compounds	compound	NOUN
dti-2638	93	13	capable	capable	ADJ
dti-2638	93	14	of	of	ADP
dti-2638	93	15	virtual	virtual	ADJ
dti-2638	93	16	binding	binding	NOUN
dti-2638	93	17	at	at	ADP
dti-2638	93	18	the	the	DET
dti-2638	93	19	selected	select	VERB
dti-2638	93	20	target	target	NOUN
dti-2638	93	21	site	site	NOUN
dti-2638	93	22	on	on	ADP
dti-2638	93	23	nor	nor	CCONJ
dti-2638	93	24	(	(	PUNCT
dti-2638	93	25	fig	fig	NOUN
dti-2638	93	26	.	.	NOUN
dti-2638	94	1	2	2	X
dti-2638	94	2	)	)	PUNCT
dti-2638	94	3	using	use	VERB
dti-2638	94	4	atomnet	atomnet	PROPN
dti-2638	94	5	®	®	NOUN
dti-2638	94	6	.	.	PUNCT
dti-2638	95	1	top	top	ADJ
dti-2638	95	2	scoring	scoring	NOUN
dti-2638	95	3	compounds	compound	NOUN
dti-2638	95	4	were	be	AUX
dti-2638	95	5	clustered	cluster	VERB
dti-2638	95	6	and	and	CCONJ
dti-2638	95	7	filtered	filter	VERB
dti-2638	95	8	to	to	PART
dti-2638	95	9	arrive	arrive	VERB
dti-2638	95	10	at	at	ADP
dti-2638	95	11	a	a	DET
dti-2638	95	12	final	final	ADJ
dti-2638	95	13	subset	subset	NOUN
dti-2638	95	14	of	of	ADP
dti-2638	95	15	85	85	NUM
dti-2638	95	16	deliverable	deliverable	ADJ
dti-2638	95	17	compounds	compound	NOUN
dti-2638	95	18	.	.	PUNCT
dti-2638	96	1	test	test	NOUN
dti-2638	96	2	compounds	compound	VERB
dti-2638	96	3	ninety	ninety	NUM
dti-2638	96	4	-	-	PUNCT
dti-2638	96	5	six	six	NUM
dti-2638	96	6	compounds	compound	NOUN
dti-2638	96	7	showing	show	VERB
dti-2638	96	8	in	in	ADP
dti-2638	96	9	silico	silico	NOUN
dti-2638	96	10	affinity	affinity	NOUN
dti-2638	96	11	to	to	ADP
dti-2638	96	12	lasr	lasr	PROPN
dti-2638	96	13	(	(	PUNCT
dti-2638	96	14	supplementary	supplementary	ADJ
dti-2638	96	15	table	table	NOUN
dti-2638	96	16	s1	s1	NOUN
dti-2638	96	17	,	,	PUNCT
dti-2638	96	18	list	list	NOUN
dti-2638	96	19	of	of	ADP
dti-2638	96	20	predicted	predict	VERB
dti-2638	96	21	lasr	lasr	PROPN
dti-2638	96	22	inhibitors	inhibitor	NOUN
dti-2638	96	23	subjected	subject	VERB
dti-2638	96	24	to	to	ADP
dti-2638	96	25	wet	wet	ADJ
dti-2638	96	26	-	-	PUNCT
dti-2638	96	27	lab	lab	NOUN
dti-2638	96	28	assay	assay	NOUN
dti-2638	96	29	)	)	PUNCT
dti-2638	96	30	and	and	CCONJ
dti-2638	96	31	85	85	NUM
dti-2638	96	32	compounds	compound	NOUN
dti-2638	96	33	showing	show	VERB
dti-2638	96	34	in	in	ADP
dti-2638	96	35	silico	silico	NOUN
dti-2638	96	36	fig	fig	NOUN
dti-2638	96	37	.	.	PUNCT
dti-2638	97	1	1	1	NUM
dti-2638	97	2	quorum	quorum	NOUN
dti-2638	97	3	sensing	sense	VERB
dti-2638	97	4	receptor	receptor	NOUN
dti-2638	97	5	lasr	lasr	PROPN
dti-2638	97	6	.	.	PUNCT
dti-2638	98	1	a	a	PRON
dti-2638	98	2	)	)	PUNCT
dti-2638	98	3	the	the	DET
dti-2638	98	4	structure	structure	NOUN
dti-2638	98	5	of	of	ADP
dti-2638	98	6	lasr	lasr	PROPN
dti-2638	98	7	(	(	PUNCT
dti-2638	98	8	green	green	ADJ
dti-2638	98	9	)	)	PUNCT
dti-2638	98	10	in	in	ADP
dti-2638	98	11	complex	complex	NOUN
dti-2638	98	12	with	with	ADP
dti-2638	98	13	its	its	PRON
dti-2638	98	14	natural	natural	ADJ
dti-2638	98	15	ligand	ligand	ADJ
dti-2638	98	16	3o	3o	NUM
dti-2638	98	17	-	-	PUNCT
dti-2638	98	18	c12	c12	NOUN
dti-2638	98	19	-	-	PUNCT
dti-2638	98	20	hsl	hsl	NOUN
dti-2638	98	21	(	(	PUNCT
dti-2638	98	22	tan	tan	PROPN
dti-2638	98	23	)	)	PUNCT
dti-2638	98	24	.	.	PUNCT
dti-2638	99	1	coordinates	coordinate	NOUN
dti-2638	99	2	taken	take	VERB
dti-2638	99	3	from	from	ADP
dti-2638	99	4	pdb	pdb	PROPN
dti-2638	99	5	3ix3	3ix3	NUM
dti-2638	99	6	.	.	PUNCT
dti-2638	100	1	b	b	X
dti-2638	100	2	)	)	PUNCT
dti-2638	100	3	the	the	DET
dti-2638	100	4	binding	bind	VERB
dti-2638	100	5	site	site	NOUN
dti-2638	100	6	of	of	ADP
dti-2638	100	7	lasr	lasr	PROPN
dti-2638	100	8	with	with	ADP
dti-2638	100	9	the	the	DET
dti-2638	100	10	3o	3o	NUM
dti-2638	100	11	-	-	PUNCT
dti-2638	100	12	c12	c12	NOUN
dti-2638	100	13	-	-	PUNCT
dti-2638	100	14	hsl	hsl	NOUN
dti-2638	100	15	ligand	ligand	NOUN
dti-2638	100	16	is	be	AUX
dti-2638	100	17	present	present	ADJ
dti-2638	100	18	.	.	PUNCT
dti-2638	101	1	residues	residue	NOUN
dti-2638	101	2	expected	expect	VERB
dti-2638	101	3	to	to	PART
dti-2638	101	4	make	make	VERB
dti-2638	101	5	direct	direct	ADJ
dti-2638	101	6	contacts	contact	NOUN
dti-2638	101	7	with	with	ADP
dti-2638	101	8	ligands	ligand	NOUN
dti-2638	101	9	are	be	AUX
dti-2638	101	10	labelled	label	VERB
dti-2638	101	11	.	.	PUNCT
dti-2638	101	12	small	small	ADJ
dti-2638	101	13	-	-	PUNCT
dti-2638	101	14	molecule	molecule	NOUN
dti-2638	101	15	inhibitors	inhibitor	NOUN
dti-2638	101	16	of	of	ADP
dti-2638	101	17	pseudomonas	pseudomona	NOUN
dti-2638	101	18	aeruginosa	aeruginosa	NOUN
dti-2638	101	19	lasr	lasr	PROPN
dti-2638	101	20	or	or	CCONJ
dti-2638	101	21	nor104	nor104	PROPN
dti-2638	101	22	©	©	PROPN
dti-2638	101	23	2023	2023	NUM
dti-2638	101	24	the	the	DET
dti-2638	101	25	authors	author	NOUN
dti-2638	101	26	.	.	PUNCT
dti-2638	102	1	drug	drug	NOUN
dti-2638	102	2	target	target	NOUN
dti-2638	102	3	insights	insight	NOUN
dti-2638	102	4	issn	issn	VERB
dti-2638	102	5	1177	1177	NUM
dti-2638	102	6	-	-	SYM
dti-2638	102	7	3928	3928	NUM
dti-2638	102	8	www.aboutscience.eu/dti	www.aboutscience.eu/dti	NOUN
dti-2638	102	9	affinity	affinity	NOUN
dti-2638	102	10	to	to	ADP
dti-2638	102	11	nor	nor	CCONJ
dti-2638	102	12	(	(	PUNCT
dti-2638	102	13	supplementary	supplementary	ADJ
dti-2638	102	14	table	table	NOUN
dti-2638	102	15	s2	s2	PROPN
dti-2638	102	16	,	,	PUNCT
dti-2638	102	17	list	list	NOUN
dti-2638	102	18	of	of	ADP
dti-2638	102	19	predicted	predict	VERB
dti-2638	102	20	nor	nor	CCONJ
dti-2638	102	21	inhibitors	inhibitor	NOUN
dti-2638	102	22	subjected	subject	VERB
dti-2638	102	23	to	to	ADP
dti-2638	102	24	wet	wet	ADJ
dti-2638	102	25	-	-	PUNCT
dti-2638	102	26	lab	lab	NOUN
dti-2638	102	27	assay	assay	NOUN
dti-2638	102	28	)	)	PUNCT
dti-2638	102	29	were	be	AUX
dti-2638	102	30	ordered	order	VERB
dti-2638	102	31	in	in	ADP
dti-2638	102	32	physical	physical	ADJ
dti-2638	102	33	form	form	NOUN
dti-2638	102	34	from	from	ADP
dti-2638	102	35	enamine	enamine	NOUN
dti-2638	102	36	(	(	PUNCT
dti-2638	102	37	kyiv	kyiv	ADJ
dti-2638	102	38	,	,	PUNCT
dti-2638	102	39	ukraine	ukraine	NOUN
dti-2638	102	40	)	)	PUNCT
dti-2638	102	41	and	and	CCONJ
dti-2638	102	42	mcule	mcule	ADJ
dti-2638	102	43	(	(	PUNCT
dti-2638	102	44	budapest	budapest	ADJ
dti-2638	102	45	,	,	PUNCT
dti-2638	102	46	hungary	hungary	PROPN
dti-2638	102	47	)	)	PUNCT
dti-2638	102	48	,	,	PUNCT
dti-2638	102	49	respectively	respectively	ADV
dti-2638	102	50	.	.	PUNCT
dti-2638	103	1	test	test	NOUN
dti-2638	103	2	compounds	compound	NOUN
dti-2638	103	3	were	be	AUX
dti-2638	103	4	stored	store	VERB
dti-2638	103	5	in	in	ADP
dti-2638	103	6	the	the	DET
dti-2638	103	7	refrigerator	refrigerator	NOUN
dti-2638	103	8	and	and	CCONJ
dti-2638	103	9	reconstituted	reconstitute	VERB
dti-2638	103	10	in	in	ADP
dti-2638	103	11	dimethyl	dimethyl	NOUN
dti-2638	103	12	sulfoxide	sulfoxide	NOUN
dti-2638	103	13	(	(	PUNCT
dti-2638	103	14	dmso	dmso	NOUN
dti-2638	103	15	;	;	PUNCT
dti-2638	103	16	500	500	NUM
dti-2638	103	17	-	-	SYM
dti-2638	103	18	1000	1000	NUM
dti-2638	103	19	µl	µl	NOUN
dti-2638	103	20	)	)	PUNCT
dti-2638	103	21	(	(	PUNCT
dti-2638	103	22	merck	merck	NOUN
dti-2638	103	23	)	)	PUNCT
dti-2638	103	24	on	on	ADP
dti-2638	103	25	the	the	DET
dti-2638	103	26	day	day	NOUN
dti-2638	103	27	of	of	ADP
dti-2638	103	28	assay	assay	NOUN
dti-2638	103	29	.	.	PUNCT
dti-2638	104	1	bacterial	bacterial	ADJ
dti-2638	104	2	strain	strain	NOUN
dti-2638	104	3	the	the	DET
dti-2638	104	4	p.	p.	PROPN
dti-2638	104	5	aeruginosa	aeruginosa	PROPN
dti-2638	104	6	strain	strain	NOUN
dti-2638	104	7	used	use	VERB
dti-2638	104	8	in	in	ADP
dti-2638	104	9	this	this	DET
dti-2638	104	10	study	study	NOUN
dti-2638	104	11	was	be	AUX
dti-2638	104	12	sourced	source	VERB
dti-2638	104	13	from	from	ADP
dti-2638	104	14	our	our	PRON
dti-2638	104	15	internal	internal	ADJ
dti-2638	104	16	culture	culture	NOUN
dti-2638	104	17	collection	collection	NOUN
dti-2638	104	18	,	,	PUNCT
dti-2638	104	19	which	which	PRON
dti-2638	104	20	has	have	AUX
dti-2638	104	21	been	be	AUX
dti-2638	104	22	characterized	characterize	VERB
dti-2638	104	23	by	by	ADP
dti-2638	104	24	us	we	PRON
dti-2638	104	25	for	for	ADP
dti-2638	104	26	its	its	PRON
dti-2638	104	27	antibiotic	antibiotic	ADJ
dti-2638	104	28	susceptibility	susceptibility	NOUN
dti-2638	104	29	/	/	SYM
dti-2638	104	30	resistance	resistance	NOUN
dti-2638	104	31	,	,	PUNCT
dti-2638	104	32	pigment	pigment	NOUN
dti-2638	104	33	production	production	NOUN
dti-2638	104	34	,	,	PUNCT
dti-2638	104	35	and	and	CCONJ
dti-2638	104	36	certain	certain	ADJ
dti-2638	104	37	other	other	ADJ
dti-2638	104	38	virulence	virulence	NOUN
dti-2638	104	39	traits	trait	NOUN
dti-2638	104	40	.	.	PUNCT
dti-2638	105	1	its	its	PRON
dti-2638	105	2	antibiogram	antibiogram	PROPN
dti-2638	105	3	(	(	PUNCT
dti-2638	105	4	online	online	NOUN
dti-2638	105	5	)	)	PUNCT
dti-2638	105	6	generated	generate	VERB
dti-2638	105	7	through	through	ADP
dti-2638	105	8	a	a	DET
dti-2638	105	9	disc	disc	NOUN
dti-2638	105	10	-	-	PUNCT
dti-2638	105	11	diffusion	diffusion	NOUN
dti-2638	105	12	assay	assay	NOUN
dti-2638	105	13	performed	perform	VERB
dti-2638	105	14	as	as	ADP
dti-2638	105	15	per	per	ADP
dti-2638	105	16	the	the	DET
dti-2638	105	17	national	national	PROPN
dti-2638	105	18	committee	committee	PROPN
dti-2638	105	19	for	for	ADP
dti-2638	105	20	clinical	clinical	ADJ
dti-2638	105	21	laboratory	laboratory	NOUN
dti-2638	105	22	standards	standard	NOUN
dti-2638	105	23	(	(	PUNCT
dti-2638	105	24	nccls	nccls	NOUN
dti-2638	105	25	)	)	PUNCT
dti-2638	105	26	guidelines	guideline	NOUN
dti-2638	105	27	revealed	reveal	VERB
dti-2638	105	28	it	it	PRON
dti-2638	105	29	to	to	PART
dti-2638	105	30	be	be	AUX
dti-2638	105	31	resistant	resistant	ADJ
dti-2638	105	32	to	to	ADP
dti-2638	105	33	eight	eight	NUM
dti-2638	105	34	antibiotics	antibiotic	NOUN
dti-2638	105	35	(	(	PUNCT
dti-2638	105	36	cotrimoxazole	cotrimoxazole	PROPN
dti-2638	105	37	,	,	PUNCT
dti-2638	105	38	augmentin	augmentin	PROPN
dti-2638	105	39	,	,	PUNCT
dti-2638	105	40	nitrofurantoin	nitrofurantoin	NOUN
dti-2638	105	41	,	,	PUNCT
dti-2638	105	42	ampicillin	ampicillin	PROPN
dti-2638	105	43	,	,	PUNCT
dti-2638	105	44	chloramphenicol	chloramphenicol	NOUN
dti-2638	105	45	,	,	PUNCT
dti-2638	105	46	clindamycin	clindamycin	NOUN
dti-2638	105	47	,	,	PUNCT
dti-2638	105	48	cefixime	cefixime	NOUN
dti-2638	105	49	,	,	PUNCT
dti-2638	105	50	and	and	CCONJ
dti-2638	105	51	vancomycin	vancomycin	PROPN
dti-2638	105	52	)	)	PUNCT
dti-2638	105	53	belonging	belong	VERB
dti-2638	105	54	to	to	ADP
dti-2638	105	55	five	five	NUM
dti-2638	105	56	different	different	ADJ
dti-2638	105	57	classes	class	NOUN
dti-2638	105	58	.	.	PUNCT
dti-2638	106	1	hence	hence	ADV
dti-2638	106	2	it	it	PRON
dti-2638	106	3	can	can	AUX
dti-2638	106	4	be	be	AUX
dti-2638	106	5	described	describe	VERB
dti-2638	106	6	as	as	ADP
dti-2638	106	7	a	a	DET
dti-2638	106	8	multidrug	multidrug	NOUN
dti-2638	106	9	-	-	PUNCT
dti-2638	106	10	resistant	resistant	ADJ
dti-2638	106	11	(	(	PUNCT
dti-2638	106	12	mdr	mdr	NOUN
dti-2638	106	13	)	)	PUNCT
dti-2638	106	14	strain	strain	NOUN
dti-2638	106	15	.	.	PUNCT
dti-2638	107	1	as	as	SCONJ
dti-2638	107	2	reported	report	VERB
dti-2638	107	3	in	in	ADP
dti-2638	107	4	our	our	PRON
dti-2638	107	5	earlier	early	ADJ
dti-2638	107	6	publications	publication	NOUN
dti-2638	107	7	(	(	PUNCT
dti-2638	107	8	27,38	27,38	NUM
dti-2638	107	9	)	)	PUNCT
dti-2638	107	10	with	with	ADP
dti-2638	107	11	this	this	DET
dti-2638	107	12	strain	strain	NOUN
dti-2638	107	13	,	,	PUNCT
dti-2638	107	14	it	it	PRON
dti-2638	107	15	is	be	AUX
dti-2638	107	16	a	a	DET
dti-2638	107	17	haemolytic	haemolytic	ADJ
dti-2638	107	18	strain	strain	NOUN
dti-2638	107	19	capable	capable	ADJ
dti-2638	107	20	of	of	ADP
dti-2638	107	21	producing	produce	VERB
dti-2638	107	22	the	the	DET
dti-2638	107	23	qs	qs	ADJ
dti-2638	107	24	-	-	PUNCT
dti-2638	107	25	regulated	regulated	ADJ
dti-2638	107	26	pigments	pigment	NOUN
dti-2638	107	27	(	(	PUNCT
dti-2638	107	28	pyocyanin	pyocyanin	NOUN
dti-2638	107	29	and	and	CCONJ
dti-2638	107	30	pyoverdine	pyoverdine	ADJ
dti-2638	107	31	)	)	PUNCT
dti-2638	107	32	,	,	PUNCT
dti-2638	107	33	and	and	CCONJ
dti-2638	107	34	also	also	ADV
dti-2638	107	35	of	of	ADP
dti-2638	107	36	biofilm	biofilm	NOUN
dti-2638	107	37	formation	formation	NOUN
dti-2638	107	38	.	.	PUNCT
dti-2638	108	1	we	we	PRON
dti-2638	108	2	maintained	maintain	VERB
dti-2638	108	3	this	this	DET
dti-2638	108	4	bacterium	bacterium	NOUN
dti-2638	108	5	on	on	ADP
dti-2638	108	6	pseudomonas	pseudomona	NOUN
dti-2638	108	7	agar	agar	NOUN
dti-2638	108	8	(	(	PUNCT
dti-2638	108	9	himedia	himedia	NOUN
dti-2638	108	10	)	)	PUNCT
dti-2638	108	11	.	.	PUNCT
dti-2638	109	1	while	while	SCONJ
dti-2638	109	2	culturing	culture	VERB
dti-2638	109	3	the	the	DET
dti-2638	109	4	bacteria	bacteria	NOUN
dti-2638	109	5	for	for	ADP
dti-2638	109	6	in	in	ADP
dti-2638	109	7	vivo	vivo	NOUN
dti-2638	109	8	assay	assay	NOUN
dti-2638	109	9	,	,	PUNCT
dti-2638	109	10	they	they	PRON
dti-2638	109	11	were	be	AUX
dti-2638	109	12	grown	grow	VERB
dti-2638	109	13	in	in	ADP
dti-2638	109	14	pseudomonas	pseudomona	NOUN
dti-2638	109	15	broth	broth	NOUN
dti-2638	109	16	(	(	PUNCT
dti-2638	109	17	magnesium	magnesium	NOUN
dti-2638	109	18	chloride	chloride	NOUN
dti-2638	109	19	1.4	1.4	NUM
dti-2638	109	20	g	g	NOUN
dti-2638	109	21	/	/	SYM
dti-2638	109	22	l	l	NOUN
dti-2638	109	23	,	,	PUNCT
dti-2638	109	24	potassium	potassium	NOUN
dti-2638	109	25	sulphate	sulphate	NOUN
dti-2638	109	26	10	10	NUM
dti-2638	109	27	g	g	NOUN
dti-2638	109	28	/	/	SYM
dti-2638	109	29	l	l	NOUN
dti-2638	109	30	,	,	PUNCT
dti-2638	109	31	peptic	peptic	ADJ
dti-2638	109	32	digest	digest	NOUN
dti-2638	109	33	of	of	ADP
dti-2638	109	34	animal	animal	NOUN
dti-2638	109	35	tissue	tissue	NOUN
dti-2638	109	36	20	20	NUM
dti-2638	109	37	g	g	NOUN
dti-2638	109	38	/	/	SYM
dti-2638	109	39	l	l	NOUN
dti-2638	109	40	,	,	PUNCT
dti-2638	109	41	ph	ph	PROPN
dti-2638	109	42	7.0	7.0	NUM
dti-2638	109	43	±	±	NUM
dti-2638	109	44	0.2	0.2	NUM
dti-2638	109	45	)	)	PUNCT
dti-2638	109	46	.	.	PUNCT
dti-2638	110	1	nematode	nematode	NOUN
dti-2638	110	2	host	host	NOUN
dti-2638	110	3	c.	c.	PROPN
dti-2638	110	4	elegans	elegan	NOUN
dti-2638	110	5	(	(	PUNCT
dti-2638	110	6	n2	n2	PROPN
dti-2638	110	7	bristol	bristol	PROPN
dti-2638	110	8	)	)	PUNCT
dti-2638	110	9	was	be	AUX
dti-2638	110	10	used	use	VERB
dti-2638	110	11	as	as	ADP
dti-2638	110	12	the	the	DET
dti-2638	110	13	model	model	NOUN
dti-2638	110	14	host	host	NOUN
dti-2638	110	15	in	in	ADP
dti-2638	110	16	this	this	DET
dti-2638	110	17	study	study	NOUN
dti-2638	110	18	.	.	PUNCT
dti-2638	111	1	worms	worm	NOUN
dti-2638	111	2	were	be	AUX
dti-2638	111	3	maintained	maintain	VERB
dti-2638	111	4	on	on	ADP
dti-2638	111	5	nematode	nematode	ADJ
dti-2638	111	6	growth	growth	NOUN
dti-2638	111	7	medium	medium	NOUN
dti-2638	111	8	(	(	PUNCT
dti-2638	111	9	ngm	ngm	ADJ
dti-2638	111	10	):	):	PUNCT
dti-2638	111	11	3	3	NUM
dti-2638	111	12	g	g	NOUN
dti-2638	111	13	/	/	SYM
dti-2638	111	14	l	l	NOUN
dti-2638	111	15	nacl	nacl	NOUN
dti-2638	111	16	(	(	PUNCT
dti-2638	111	17	himedia	himedia	NOUN
dti-2638	111	18	,	,	PUNCT
dti-2638	111	19	mb023	mb023	NOUN
dti-2638	111	20	-	-	PUNCT
dti-2638	111	21	500	500	NUM
dti-2638	111	22	g	g	NOUN
dti-2638	111	23	)	)	PUNCT
dti-2638	111	24	,	,	PUNCT
dti-2638	111	25	2.5	2.5	NUM
dti-2638	111	26	g	g	NOUN
dti-2638	111	27	/	/	SYM
dti-2638	111	28	l	l	NOUN
dti-2638	111	29	peptone	peptone	NOUN
dti-2638	111	30	(	(	PUNCT
dti-2638	111	31	himedia	himedia	PROPN
dti-2638	111	32	)	)	PUNCT
dti-2638	111	33	,	,	PUNCT
dti-2638	111	34	17	17	NUM
dti-2638	111	35	g	g	NOUN
dti-2638	111	36	/	/	SYM
dti-2638	111	37	l	l	NOUN
dti-2638	111	38	agar	agar	NOUN
dti-2638	111	39	-	-	PUNCT
dti-2638	111	40	agar	agar	NOUN
dti-2638	111	41	(	(	PUNCT
dti-2638	111	42	himedia	himedia	PROPN
dti-2638	111	43	)	)	PUNCT
dti-2638	111	44	,	,	PUNCT
dti-2638	111	45	1	1	NUM
dti-2638	111	46	m	m	NOUN
dti-2638	111	47	cacl2	cacl2	NOUN
dti-2638	111	48	(	(	PUNCT
dti-2638	111	49	himedia	himedia	PROPN
dti-2638	111	50	)	)	PUNCT
dti-2638	111	51	,	,	PUNCT
dti-2638	111	52	1	1	NUM
dti-2638	111	53	m	m	NOUN
dti-2638	111	54	mgso4	mgso4	NOUN
dti-2638	111	55	(	(	PUNCT
dti-2638	111	56	merck	merck	PROPN
dti-2638	111	57	)	)	PUNCT
dti-2638	111	58	,	,	PUNCT
dti-2638	111	59	5	5	NUM
dti-2638	111	60	mg	mg	NUM
dti-2638	111	61	/	/	SYM
dti-2638	111	62	ml	ml	NOUN
dti-2638	111	63	cholesterol	cholesterol	NOUN
dti-2638	111	64	(	(	PUNCT
dti-2638	111	65	himedia	himedia	PROPN
dti-2638	111	66	)	)	PUNCT
dti-2638	111	67	,	,	PUNCT
dti-2638	111	68	1	1	NUM
dti-2638	111	69	m	m	NOUN
dti-2638	111	70	phosphate	phosphate	ADJ
dti-2638	111	71	buffer	buffer	NOUN
dti-2638	111	72	of	of	ADP
dti-2638	111	73	ph	ph	ADJ
dti-2638	111	74	6	6	NUM
dti-2638	111	75	,	,	PUNCT
dti-2638	111	76	agar	agar	NOUN
dti-2638	111	77	plate	plate	NOUN
dti-2638	111	78	with	with	ADP
dti-2638	111	79	escherichia	escherichia	NOUN
dti-2638	111	80	coli	coli	NOUN
dti-2638	111	81	op50	op50	PROPN
dti-2638	111	82	(	(	PUNCT
dti-2638	111	83	labtie	labtie	PROPN
dti-2638	111	84	b.v	b.v	PROPN
dti-2638	111	85	.	.	PROPN
dti-2638	111	86	,	,	PUNCT
dti-2638	111	87	the	the	DET
dti-2638	111	88	netherlands	netherlands	PROPN
dti-2638	111	89	)	)	PUNCT
dti-2638	111	90	as	as	ADP
dti-2638	111	91	food	food	NOUN
dti-2638	111	92	.	.	PUNCT
dti-2638	112	1	for	for	ADP
dti-2638	112	2	synchronization	synchronization	NOUN
dti-2638	112	3	of	of	ADP
dti-2638	112	4	the	the	DET
dti-2638	112	5	worm	worm	NOUN
dti-2638	112	6	population	population	NOUN
dti-2638	112	7	,	,	PUNCT
dti-2638	112	8	adult	adult	NOUN
dti-2638	112	9	worms	worm	NOUN
dti-2638	112	10	from	from	ADP
dti-2638	112	11	a	a	DET
dti-2638	112	12	4to	4to	ADJ
dti-2638	112	13	5	5	NUM
dti-2638	112	14	-	-	PUNCT
dti-2638	112	15	day	day	NOUN
dti-2638	112	16	-	-	PUNCT
dti-2638	112	17	old	old	ADJ
dti-2638	112	18	ngm	ngm	PROPN
dti-2638	112	19	plate	plate	NOUN
dti-2638	112	20	were	be	AUX
dti-2638	112	21	first	first	ADV
dti-2638	112	22	washed	wash	VERB
dti-2638	112	23	with	with	ADP
dti-2638	112	24	distilled	distilled	ADJ
dti-2638	112	25	water	water	NOUN
dti-2638	112	26	,	,	PUNCT
dti-2638	112	27	and	and	CCONJ
dti-2638	112	28	then	then	ADV
dti-2638	112	29	treated	treat	VERB
dti-2638	112	30	with	with	ADP
dti-2638	112	31	1	1	NUM
dti-2638	112	32	ml	ml	NOUN
dti-2638	112	33	of	of	ADP
dti-2638	112	34	bleaching	bleaching	NOUN
dti-2638	112	35	solution	solution	NOUN
dti-2638	112	36	(	(	PUNCT
dti-2638	112	37	water	water	NOUN
dti-2638	112	38	+	+	CCONJ
dti-2638	112	39	4	4	NUM
dti-2638	112	40	%	%	NOUN
dti-2638	112	41	naocl	naocl	NOUN
dti-2638	112	42	[	[	X
dti-2638	112	43	merck	merck	X
dti-2638	112	44	]	]	X
dti-2638	112	45	+1	+1	PROPN
dti-2638	112	46	n	n	PROPN
dti-2638	112	47	naoh	naoh	NOUN
dti-2638	112	48	[	[	X
dti-2638	112	49	himedia	himedia	X
dti-2638	112	50	]	]	PUNCT
dti-2638	112	51	in	in	ADP
dti-2638	112	52	3:1:1	3:1:1	NUM
dti-2638	112	53	proportion	proportion	NOUN
dti-2638	112	54	)	)	PUNCT
dti-2638	112	55	,	,	PUNCT
dti-2638	112	56	followed	follow	VERB
dti-2638	112	57	by	by	ADP
dti-2638	112	58	centrifugation	centrifugation	NOUN
dti-2638	112	59	(	(	PUNCT
dti-2638	112	60	1,500	1,500	NUM
dti-2638	112	61	rpm	rpm	NOUN
dti-2638	112	62	at	at	ADP
dti-2638	112	63	22	22	NUM
dti-2638	112	64	°	°	NOUN
dti-2638	112	65	c	c	NOUN
dti-2638	112	66	)	)	PUNCT
dti-2638	112	67	for	for	ADP
dti-2638	112	68	1	1	NUM
dti-2638	112	69	min	min	NOUN
dti-2638	112	70	.	.	PROPN
dti-2638	112	71	eggs	egg	NOUN
dti-2638	112	72	in	in	ADP
dti-2638	112	73	the	the	DET
dti-2638	112	74	resultant	resultant	NOUN
dti-2638	112	75	pellet	pellet	NOUN
dti-2638	112	76	were	be	AUX
dti-2638	112	77	washed	wash	VERB
dti-2638	112	78	multiple	multiple	ADJ
dti-2638	112	79	times	time	NOUN
dti-2638	112	80	with	with	ADP
dti-2638	112	81	sterile	sterile	ADJ
dti-2638	112	82	distilled	distil	VERB
dti-2638	112	83	water	water	NOUN
dti-2638	112	84	,	,	PUNCT
dti-2638	112	85	followed	follow	VERB
dti-2638	112	86	by	by	ADP
dti-2638	112	87	transfer	transfer	NOUN
dti-2638	112	88	onto	onto	ADP
dti-2638	112	89	a	a	DET
dti-2638	112	90	new	new	ADJ
dti-2638	112	91	ngm	ngm	PROPN
dti-2638	112	92	plate	plate	NOUN
dti-2638	112	93	seeded	seed	VERB
dti-2638	112	94	with	with	ADP
dti-2638	112	95	e.	e.	PROPN
dti-2638	112	96	coli	coli	PROPN
dti-2638	112	97	op50	op50	PROPN
dti-2638	112	98	.	.	PUNCT
dti-2638	113	1	l3	l3	PROPN
dti-2638	113	2	-	-	PUNCT
dti-2638	113	3	l4	l4	PROPN
dti-2638	113	4	stage	stage	NOUN
dti-2638	113	5	worms	worm	NOUN
dti-2638	113	6	appearing	appear	VERB
dti-2638	113	7	on	on	ADP
dti-2638	113	8	this	this	DET
dti-2638	113	9	plate	plate	NOUN
dti-2638	113	10	after	after	SCONJ
dti-2638	113	11	2	2	NUM
dti-2638	113	12	-	-	SYM
dti-2638	113	13	3	3	NUM
dti-2638	113	14	days	day	NOUN
dti-2638	113	15	of	of	ADP
dti-2638	113	16	incubation	incubation	NOUN
dti-2638	113	17	at	at	ADP
dti-2638	113	18	22	22	NUM
dti-2638	113	19	°	°	NOUN
dti-2638	113	20	c	c	NOUN
dti-2638	113	21	were	be	AUX
dti-2638	113	22	used	use	VERB
dti-2638	113	23	for	for	ADP
dti-2638	113	24	further	further	ADJ
dti-2638	113	25	experimentation	experimentation	NOUN
dti-2638	113	26	.	.	PUNCT
dti-2638	114	1	virulence	virulence	NOUN
dti-2638	114	2	assay	assay	PROPN
dti-2638	114	3	p.	p.	PROPN
dti-2638	114	4	aeruginosa	aeruginosa	PROPN
dti-2638	114	5	grown	grow	VERB
dti-2638	114	6	in	in	ADP
dti-2638	114	7	pseudomonas	pseudomona	NOUN
dti-2638	114	8	broth	broth	NOUN
dti-2638	114	9	(	(	PUNCT
dti-2638	114	10	at	at	ADP
dti-2638	114	11	35±1	35±1	NUM
dti-2638	114	12	°	°	ADP
dti-2638	114	13	c	c	NOUN
dti-2638	114	14	for	for	ADP
dti-2638	114	15	21	21	NUM
dti-2638	114	16	hours	hour	NOUN
dti-2638	114	17	with	with	ADP
dti-2638	114	18	intermittent	intermittent	ADJ
dti-2638	114	19	shaking	shaking	NOUN
dti-2638	114	20	)	)	PUNCT
dti-2638	114	21	was	be	AUX
dti-2638	114	22	allowed	allow	VERB
dti-2638	114	23	to	to	PART
dti-2638	114	24	attack	attack	VERB
dti-2638	114	25	c.	c.	PROPN
dti-2638	114	26	elegans	elegan	NOUN
dti-2638	114	27	(	(	PUNCT
dti-2638	114	28	l3	l3	PROPN
dti-2638	114	29	-	-	ADJ
dti-2638	114	30	l4	l4	PROPN
dti-2638	114	31	stage	stage	NOUN
dti-2638	114	32	)	)	PUNCT
dti-2638	114	33	in	in	ADP
dti-2638	114	34	a	a	DET
dti-2638	114	35	24	24	NUM
dti-2638	114	36	-	-	PUNCT
dti-2638	114	37	well	well	NOUN
dti-2638	114	38	plate	plate	NOUN
dti-2638	114	39	(	(	PUNCT
dti-2638	114	40	himedia	himedia	NOUN
dti-2638	114	41	)	)	PUNCT
dti-2638	114	42	in	in	ADP
dti-2638	114	43	the	the	DET
dti-2638	114	44	presence	presence	NOUN
dti-2638	114	45	or	or	CCONJ
dti-2638	114	46	absence	absence	NOUN
dti-2638	114	47	of	of	ADP
dti-2638	114	48	test	test	NOUN
dti-2638	114	49	compounds	compound	NOUN
dti-2638	114	50	,	,	PUNCT
dti-2638	114	51	and	and	CCONJ
dti-2638	114	52	their	their	PRON
dti-2638	114	53	capacity	capacity	NOUN
dti-2638	114	54	to	to	PART
dti-2638	114	55	kill	kill	VERB
dti-2638	114	56	the	the	DET
dti-2638	114	57	worm	worm	NOUN
dti-2638	114	58	population	population	NOUN
dti-2638	114	59	was	be	AUX
dti-2638	114	60	monitored	monitor	VERB
dti-2638	114	61	over	over	ADP
dti-2638	114	62	a	a	DET
dti-2638	114	63	period	period	NOUN
dti-2638	114	64	of	of	ADP
dti-2638	114	65	5	5	NUM
dti-2638	114	66	days	day	NOUN
dti-2638	114	67	.	.	PUNCT
dti-2638	115	1	in	in	ADP
dti-2638	115	2	each	each	PRON
dti-2638	115	3	well	well	ADV
dti-2638	115	4	,	,	PUNCT
dti-2638	115	5	there	there	PRON
dti-2638	115	6	were	be	VERB
dti-2638	115	7	10	10	NUM
dti-2638	115	8	worms	worm	NOUN
dti-2638	115	9	in	in	ADP
dti-2638	115	10	m9	m9	PROPN
dti-2638	115	11	buffer	buffer	NOUN
dti-2638	115	12	(	(	PUNCT
dti-2638	115	13	3	3	NUM
dti-2638	115	14	g	g	NOUN
dti-2638	115	15	/	/	SYM
dti-2638	115	16	l	l	NOUN
dti-2638	115	17	kh2po4	kh2po4	NOUN
dti-2638	115	18	,	,	PUNCT
dti-2638	115	19	6	6	NUM
dti-2638	115	20	g	g	NOUN
dti-2638	115	21	/	/	SYM
dti-2638	115	22	l	l	NOUN
dti-2638	115	23	na2hpo4	na2hpo4	PROPN
dti-2638	115	24	,	,	PUNCT
dti-2638	115	25	5	5	NUM
dti-2638	115	26	g	g	NOUN
dti-2638	115	27	/	/	SYM
dti-2638	115	28	l	l	NOUN
dti-2638	115	29	nacl	nacl	NOUN
dti-2638	115	30	)	)	PUNCT
dti-2638	115	31	,	,	PUNCT
dti-2638	115	32	which	which	PRON
dti-2638	115	33	were	be	AUX
dti-2638	115	34	challenged	challenge	VERB
dti-2638	115	35	with	with	ADP
dti-2638	115	36	p.	p.	NOUN
dti-2638	115	37	aeruginosa	aeruginosa	PROPN
dti-2638	115	38	by	by	ADP
dti-2638	115	39	adding	add	VERB
dti-2638	115	40	100	100	NUM
dti-2638	115	41	µl	µl	ADP
dti-2638	115	42	(	(	PUNCT
dti-2638	115	43	od764	od764	PROPN
dti-2638	115	44	=	=	SYM
dti-2638	115	45	1.30	1.30	NUM
dti-2638	115	46	)	)	PUNCT
dti-2638	115	47	of	of	ADP
dti-2638	115	48	bacterial	bacterial	ADJ
dti-2638	115	49	culture	culture	NOUN
dti-2638	115	50	grown	grow	VERB
dti-2638	115	51	in	in	ADP
dti-2638	115	52	pseudomonas	pseudomona	NOUN
dti-2638	115	53	broth	broth	NOUN
dti-2638	115	54	.	.	PUNCT
dti-2638	116	1	appropriate	appropriate	ADJ
dti-2638	116	2	controls	control	NOUN
dti-2638	116	3	,	,	PUNCT
dti-2638	116	4	that	that	ADV
dti-2638	116	5	is	is	ADV
dti-2638	116	6	,	,	PUNCT
dti-2638	116	7	worms	worm	NOUN
dti-2638	116	8	,	,	PUNCT
dti-2638	116	9	exposed	expose	VERB
dti-2638	116	10	neither	neither	ADV
dti-2638	116	11	to	to	PART
dti-2638	116	12	test	test	VERB
dti-2638	116	13	compound	compound	VERB
dti-2638	116	14	nor	nor	CCONJ
dti-2638	116	15	to	to	ADP
dti-2638	116	16	bacteria	bacteria	NOUN
dti-2638	116	17	;	;	PUNCT
dti-2638	116	18	worms	worm	NOUN
dti-2638	116	19	exposed	expose	VERB
dti-2638	116	20	to	to	ADP
dti-2638	116	21	test	test	NOUN
dti-2638	116	22	compound	compound	NOUN
dti-2638	116	23	,	,	PUNCT
dti-2638	116	24	but	but	CCONJ
dti-2638	116	25	not	not	PART
dti-2638	116	26	to	to	ADP
dti-2638	116	27	bacterial	bacterial	ADJ
dti-2638	116	28	pathogens	pathogen	NOUN
dti-2638	116	29	(	(	PUNCT
dti-2638	116	30	toxicity	toxicity	NOUN
dti-2638	116	31	control	control	NOUN
dti-2638	116	32	)	)	PUNCT
dti-2638	116	33	;	;	PUNCT
dti-2638	116	34	worms	worm	NOUN
dti-2638	116	35	challenged	challenge	VERB
dti-2638	116	36	with	with	ADP
dti-2638	116	37	bacteria	bacteria	NOUN
dti-2638	116	38	in	in	ADP
dti-2638	116	39	the	the	DET
dti-2638	116	40	presence	presence	NOUN
dti-2638	116	41	of	of	ADP
dti-2638	116	42	0.5	0.5	NUM
dti-2638	116	43	%	%	NOUN
dti-2638	116	44	v	v	ADP
dti-2638	116	45	/	/	SYM
dti-2638	116	46	v	v	NOUN
dti-2638	116	47	dmso	dmso	NOUN
dti-2638	116	48	(	(	PUNCT
dti-2638	116	49	vehicle	vehicle	NOUN
dti-2638	116	50	control	control	NOUN
dti-2638	116	51	)	)	PUNCT
dti-2638	116	52	;	;	PUNCT
dti-2638	116	53	and	and	CCONJ
dti-2638	116	54	worms	worm	NOUN
dti-2638	116	55	challenged	challenge	VERB
dti-2638	116	56	with	with	ADP
dti-2638	116	57	bacteria	bacteria	NOUN
dti-2638	116	58	in	in	ADP
dti-2638	116	59	the	the	DET
dti-2638	116	60	presence	presence	NOUN
dti-2638	116	61	of	of	ADP
dti-2638	116	62	0.5	0.5	NUM
dti-2638	116	63	µg	µg	NOUN
dti-2638	116	64	/	/	SYM
dti-2638	116	65	ml	ml	NOUN
dti-2638	116	66	ofloxacin	ofloxacin	NOUN
dti-2638	116	67	(	(	PUNCT
dti-2638	116	68	positive	positive	ADJ
dti-2638	116	69	control	control	NOUN
dti-2638	116	70	)	)	PUNCT
dti-2638	116	71	were	be	AUX
dti-2638	116	72	also	also	ADV
dti-2638	116	73	included	include	VERB
dti-2638	116	74	in	in	ADP
dti-2638	116	75	the	the	DET
dti-2638	116	76	experiment	experiment	NOUN
dti-2638	116	77	.	.	PUNCT
dti-2638	117	1	incubation	incubation	NOUN
dti-2638	117	2	was	be	AUX
dti-2638	117	3	carried	carry	VERB
dti-2638	117	4	out	out	ADP
dti-2638	117	5	at	at	ADP
dti-2638	117	6	22	22	NUM
dti-2638	117	7	°	°	NOUN
dti-2638	117	8	c	c	NOUN
dti-2638	117	9	.	.	PUNCT
dti-2638	118	1	the	the	DET
dti-2638	118	2	number	number	NOUN
dti-2638	118	3	of	of	ADP
dti-2638	118	4	dead	dead	ADJ
dti-2638	118	5	vs.	vs.	ADP
dti-2638	118	6	live	live	ADJ
dti-2638	118	7	worms	worm	NOUN
dti-2638	118	8	was	be	AUX
dti-2638	118	9	counted	count	VERB
dti-2638	118	10	every	every	DET
dti-2638	118	11	day	day	NOUN
dti-2638	118	12	for	for	ADP
dti-2638	118	13	5	5	NUM
dti-2638	118	14	days	day	NOUN
dti-2638	118	15	by	by	ADP
dti-2638	118	16	putting	put	VERB
dti-2638	118	17	the	the	DET
dti-2638	118	18	plate	plate	NOUN
dti-2638	118	19	with	with	ADP
dti-2638	118	20	lid	lid	NOUN
dti-2638	118	21	under	under	ADP
dti-2638	118	22	a	a	DET
dti-2638	118	23	light	light	ADJ
dti-2638	118	24	microscope	microscope	NOUN
dti-2638	118	25	4×	4×	NOUN
dti-2638	118	26	objective	objective	NOUN
dti-2638	118	27	.	.	PUNCT
dti-2638	119	1	straight	straight	ADJ
dti-2638	119	2	non	non	ADJ
dti-2638	119	3	-	-	ADJ
dti-2638	119	4	moving	moving	ADJ
dti-2638	119	5	worms	worm	NOUN
dti-2638	119	6	were	be	AUX
dti-2638	119	7	considered	consider	VERB
dti-2638	119	8	to	to	PART
dti-2638	119	9	be	be	AUX
dti-2638	119	10	dead	dead	ADJ
dti-2638	119	11	.	.	PUNCT
dti-2638	120	1	plates	plate	NOUN
dti-2638	120	2	were	be	AUX
dti-2638	120	3	gently	gently	ADV
dti-2638	120	4	tapped	tap	VERB
dti-2638	120	5	to	to	PART
dti-2638	120	6	confirm	confirm	VERB
dti-2638	120	7	lack	lack	NOUN
dti-2638	120	8	of	of	ADP
dti-2638	120	9	movement	movement	NOUN
dti-2638	120	10	in	in	ADP
dti-2638	120	11	the	the	DET
dti-2638	120	12	apparently	apparently	ADV
dti-2638	120	13	dead	dead	ADJ
dti-2638	120	14	worms	worm	NOUN
dti-2638	120	15	.	.	PUNCT
dti-2638	121	1	on	on	ADP
dti-2638	121	2	the	the	DET
dti-2638	121	3	last	last	ADJ
dti-2638	121	4	day	day	NOUN
dti-2638	121	5	of	of	ADP
dti-2638	121	6	the	the	DET
dti-2638	121	7	experiment	experiment	NOUN
dti-2638	121	8	,	,	PUNCT
dti-2638	121	9	when	when	SCONJ
dti-2638	121	10	plates	plate	NOUN
dti-2638	121	11	could	could	AUX
dti-2638	121	12	be	be	AUX
dti-2638	121	13	opened	open	VERB
dti-2638	121	14	,	,	PUNCT
dti-2638	121	15	their	their	PRON
dti-2638	121	16	death	death	NOUN
dti-2638	121	17	was	be	AUX
dti-2638	121	18	also	also	ADV
dti-2638	121	19	confirmed	confirm	VERB
dti-2638	121	20	by	by	ADP
dti-2638	121	21	prodding	prod	VERB
dti-2638	121	22	them	they	PRON
dti-2638	121	23	with	with	ADP
dti-2638	121	24	a	a	DET
dti-2638	121	25	straight	straight	ADJ
dti-2638	121	26	wire	wire	NOUN
dti-2638	121	27	,	,	PUNCT
dti-2638	121	28	wherein	wherein	SCONJ
dti-2638	121	29	no	no	DET
dti-2638	121	30	movement	movement	NOUN
dti-2638	121	31	was	be	AUX
dti-2638	121	32	taken	take	VERB
dti-2638	121	33	as	as	ADP
dti-2638	121	34	confirmation	confirmation	NOUN
dti-2638	121	35	of	of	ADP
dti-2638	121	36	death	death	NOUN
dti-2638	121	37	.	.	PUNCT
dti-2638	122	1	statistics	statistic	NOUN
dti-2638	122	2	results	result	NOUN
dti-2638	122	3	reported	report	VERB
dti-2638	122	4	are	be	AUX
dti-2638	122	5	means	mean	NOUN
dti-2638	122	6	of	of	ADP
dti-2638	122	7	three	three	NUM
dti-2638	122	8	replicates	replicate	NOUN
dti-2638	122	9	.	.	PUNCT
dti-2638	123	1	statistical	statistical	ADJ
dti-2638	123	2	significance	significance	NOUN
dti-2638	123	3	was	be	AUX
dti-2638	123	4	assessed	assess	VERB
dti-2638	123	5	through	through	ADP
dti-2638	123	6	a	a	DET
dti-2638	123	7	t	t	NOUN
dti-2638	123	8	-	-	PUNCT
dti-2638	123	9	test	test	NOUN
dti-2638	123	10	performed	perform	VERB
dti-2638	123	11	using	use	VERB
dti-2638	123	12	microsoft	microsoft	PROPN
dti-2638	123	13	excel	excel	PROPN
dti-2638	123	14	.	.	PUNCT
dti-2638	124	1	values	value	NOUN
dti-2638	124	2	of	of	ADP
dti-2638	124	3	p≤0.05	p≤0.05	NOUN
dti-2638	124	4	were	be	AUX
dti-2638	124	5	considered	consider	VERB
dti-2638	124	6	to	to	PART
dti-2638	124	7	be	be	AUX
dti-2638	124	8	significant	significant	ADJ
dti-2638	124	9	.	.	PUNCT
dti-2638	125	1	fig	fig	NOUN
dti-2638	125	2	.	.	PUNCT
dti-2638	126	1	2	2	NUM
dti-2638	126	2	nitric	nitric	ADJ
dti-2638	126	3	oxide	oxide	NOUN
dti-2638	126	4	reductase	reductase	NOUN
dti-2638	126	5	(	(	PUNCT
dti-2638	126	6	nor	nor	CCONJ
dti-2638	126	7	)	)	PUNCT
dti-2638	126	8	.	.	PUNCT
dti-2638	127	1	a	a	DET
dti-2638	127	2	)	)	PUNCT
dti-2638	127	3	crystal	crystal	NOUN
dti-2638	127	4	structure	structure	NOUN
dti-2638	127	5	of	of	ADP
dti-2638	127	6	nor	nor	CCONJ
dti-2638	127	7	complexed	complexe	VERB
dti-2638	127	8	with	with	ADP
dti-2638	127	9	an	an	DET
dti-2638	127	10	antibody	antibody	NOUN
dti-2638	127	11	fragment	fragment	NOUN
dti-2638	127	12	(	(	PUNCT
dti-2638	127	13	white	white	ADJ
dti-2638	127	14	cartoons	cartoon	NOUN
dti-2638	127	15	)	)	PUNCT
dti-2638	127	16	and	and	CCONJ
dti-2638	127	17	with	with	ADP
dti-2638	127	18	three	three	NUM
dti-2638	127	19	haem	haem	NOUN
dti-2638	127	20	cofactors	cofactor	NOUN
dti-2638	127	21	(	(	PUNCT
dti-2638	127	22	white	white	ADJ
dti-2638	127	23	sticks	stick	NOUN
dti-2638	127	24	)	)	PUNCT
dti-2638	127	25	.	.	PUNCT
dti-2638	128	1	b	b	X
dti-2638	128	2	)	)	PUNCT
dti-2638	128	3	proposed	propose	VERB
dti-2638	128	4	target	target	NOUN
dti-2638	128	5	for	for	ADP
dti-2638	128	6	virtual	virtual	ADJ
dti-2638	128	7	screen	screen	NOUN
dti-2638	128	8	(	(	PUNCT
dti-2638	128	9	white	white	ADJ
dti-2638	128	10	spheres	sphere	NOUN
dti-2638	128	11	)	)	PUNCT
dti-2638	128	12	with	with	ADP
dti-2638	128	13	surrounding	surround	VERB
dti-2638	128	14	residues	residue	NOUN
dti-2638	128	15	from	from	ADP
dti-2638	128	16	nor	nor	CCONJ
dti-2638	128	17	chains	chain	NOUN
dti-2638	128	18	b	b	NOUN
dti-2638	128	19	and	and	CCONJ
dti-2638	128	20	c	c	PROPN
dti-2638	128	21	showing	show	VERB
dti-2638	128	22	the	the	DET
dti-2638	128	23	proximity	proximity	NOUN
dti-2638	128	24	to	to	ADP
dti-2638	128	25	the	the	DET
dti-2638	128	26	haem	haem	NOUN
dti-2638	128	27	cofactors	cofactor	NOUN
dti-2638	128	28	.	.	PUNCT
dti-2638	129	1	https://www.biorxiv.org/content/10.1101/2023.06.27.546803v1.supplementary-material	https://www.biorxiv.org/content/10.1101/2023.06.27.546803v1.supplementary-material	ADJ
dti-2638	129	2	gajera	gajera	PROPN
dti-2638	129	3	et	et	PROPN
dti-2638	129	4	al	al	PROPN
dti-2638	129	5	drug	drug	PROPN
dti-2638	129	6	target	target	NOUN
dti-2638	129	7	insights	insight	NOUN
dti-2638	129	8	2023	2023	NUM
dti-2638	129	9	;	;	PUNCT
dti-2638	129	10	17	17	NUM
dti-2638	129	11	:	:	SYM
dti-2638	129	12	105	105	NUM
dti-2638	129	13	©	©	PROPN
dti-2638	129	14	2023	2023	NUM
dti-2638	129	15	the	the	DET
dti-2638	129	16	authors	author	NOUN
dti-2638	129	17	.	.	PUNCT
dti-2638	130	1	published	publish	VERB
dti-2638	130	2	by	by	ADP
dti-2638	130	3	aboutscience	aboutscience	NOUN
dti-2638	130	4	www.aboutscience.eu	www.aboutscience.eu	NOUN
dti-2638	130	5	results	result	VERB
dti-2638	130	6	anti	anti	ADJ
dti-2638	130	7	-	-	ADJ
dti-2638	130	8	pathogenic	pathogenic	ADJ
dti-2638	130	9	activity	activity	NOUN
dti-2638	130	10	of	of	ADP
dti-2638	130	11	potential	potential	ADJ
dti-2638	130	12	lasr	lasr	PROPN
dti-2638	130	13	inhibitors	inhibitor	NOUN
dti-2638	130	14	results	result	NOUN
dti-2638	130	15	of	of	ADP
dti-2638	130	16	anti	anti	ADJ
dti-2638	130	17	-	-	ADJ
dti-2638	130	18	virulence	virulence	ADJ
dti-2638	130	19	assay	assay	NOUN
dti-2638	130	20	for	for	ADP
dti-2638	130	21	all	all	DET
dti-2638	130	22	active	active	ADJ
dti-2638	130	23	compounds	compound	NOUN
dti-2638	130	24	are	be	AUX
dti-2638	130	25	presented	present	VERB
dti-2638	130	26	in	in	ADP
dti-2638	130	27	fig	fig	NOUN
dti-2638	130	28	.	.	PUNCT
dti-2638	131	1	3	3	X
dti-2638	131	2	.	.	X
dti-2638	131	3	since	since	SCONJ
dti-2638	131	4	p.	p.	PROPN
dti-2638	131	5	aeruginosa	aeruginosa	PROPN
dti-2638	131	6	strain	strain	NOUN
dti-2638	131	7	used	use	VERB
dti-2638	131	8	by	by	ADP
dti-2638	131	9	us	we	PRON
dti-2638	131	10	could	could	AUX
dti-2638	131	11	kill	kill	VERB
dti-2638	131	12	all	all	DET
dti-2638	131	13	worms	worm	NOUN
dti-2638	131	14	within	within	ADP
dti-2638	131	15	18	18	NUM
dti-2638	131	16	-	-	SYM
dti-2638	131	17	36	36	NUM
dti-2638	131	18	hours	hour	NOUN
dti-2638	131	19	,	,	PUNCT
dti-2638	131	20	any	any	DET
dti-2638	131	21	end	end	NOUN
dti-2638	131	22	-	-	PUNCT
dti-2638	131	23	point	point	NOUN
dti-2638	131	24	beyond	beyond	ADP
dti-2638	131	25	that	that	PRON
dti-2638	131	26	can	can	AUX
dti-2638	131	27	be	be	AUX
dti-2638	131	28	taken	take	VERB
dti-2638	131	29	as	as	ADP
dti-2638	131	30	valid	valid	ADJ
dti-2638	131	31	for	for	ADP
dti-2638	131	32	labelling	label	VERB
dti-2638	131	33	any	any	DET
dti-2638	131	34	compound	compound	NOUN
dti-2638	131	35	as	as	ADP
dti-2638	131	36	‘	'	PUNCT
dti-2638	131	37	active	active	ADJ
dti-2638	131	38	’	'	PUNCT
dti-2638	131	39	or	or	CCONJ
dti-2638	131	40	‘	'	PUNCT
dti-2638	131	41	inactive	inactive	ADJ
dti-2638	131	42	’	'	PUNCT
dti-2638	131	43	.	.	PUNCT
dti-2638	132	1	however	however	ADV
dti-2638	132	2	,	,	PUNCT
dti-2638	132	3	to	to	PART
dti-2638	132	4	have	have	VERB
dti-2638	132	5	more	more	ADJ
dti-2638	132	6	robust	robust	ADJ
dti-2638	132	7	interpretation	interpretation	NOUN
dti-2638	132	8	,	,	PUNCT
dti-2638	132	9	we	we	PRON
dti-2638	132	10	continued	continue	VERB
dti-2638	132	11	worm	worm	NOUN
dti-2638	132	12	counting	count	VERB
dti-2638	132	13	in	in	ADP
dti-2638	132	14	assay	assay	ADJ
dti-2638	132	15	plates	plate	NOUN
dti-2638	132	16	till	till	SCONJ
dti-2638	132	17	5	5	NUM
dti-2638	132	18	days	day	NOUN
dti-2638	132	19	for	for	ADP
dti-2638	132	20	comparing	compare	VERB
dti-2638	132	21	number	number	NOUN
dti-2638	132	22	of	of	ADP
dti-2638	132	23	live	live	ADJ
dti-2638	132	24	worms	worm	NOUN
dti-2638	132	25	in	in	ADP
dti-2638	132	26	experimental	experimental	ADJ
dti-2638	132	27	vs.	vs.	X
dti-2638	132	28	control	control	PROPN
dti-2638	132	29	wells	wells	PROPN
dti-2638	132	30	.	.	PUNCT
dti-2638	133	1	eleven	eleven	NUM
dti-2638	133	2	of	of	ADP
dti-2638	133	3	the	the	DET
dti-2638	133	4	88	88	NUM
dti-2638	133	5	dmso	dmso	ADJ
dti-2638	133	6	-	-	ADJ
dti-2638	133	7	soluble	soluble	ADJ
dti-2638	133	8	compounds	compound	NOUN
dti-2638	133	9	(	(	PUNCT
dti-2638	133	10	i.e.	i.e.	X
dti-2638	133	11	12.5	12.5	NUM
dti-2638	133	12	%	%	NOUN
dti-2638	133	13	)	)	PUNCT
dti-2638	133	14	assayed	assayed	ADJ
dti-2638	133	15	exhibited	exhibit	VERB
dti-2638	133	16	anti	anti	ADJ
dti-2638	133	17	-	-	ADJ
dti-2638	133	18	pseudomonas	pseudomonas	ADJ
dti-2638	133	19	activity	activity	NOUN
dti-2638	133	20	(	(	PUNCT
dti-2638	133	21	23%-96	23%-96	NUM
dti-2638	133	22	%	%	NOUN
dti-2638	133	23	as	as	ADP
dti-2638	133	24	per	per	ADP
dti-2638	133	25	third	third	ADJ
dti-2638	133	26	-	-	PUNCT
dti-2638	133	27	day	day	NOUN
dti-2638	133	28	end	end	NOUN
dti-2638	133	29	-	-	PUNCT
dti-2638	133	30	point	point	NOUN
dti-2638	133	31	)	)	PUNCT
dti-2638	133	32	at	at	ADP
dti-2638	133	33	25	25	NUM
dti-2638	133	34	-	-	SYM
dti-2638	133	35	50	50	NUM
dti-2638	133	36	µg	µg	NOUN
dti-2638	133	37	/	/	SYM
dti-2638	133	38	ml	ml	NOUN
dti-2638	133	39	(	(	PUNCT
dti-2638	133	40	tab	tab	NOUN
dti-2638	133	41	.	.	PUNCT
dti-2638	134	1	i	i	PRON
dti-2638	134	2	)	)	PUNCT
dti-2638	134	3	.	.	PUNCT
dti-2638	135	1	these	these	DET
dti-2638	135	2	11	11	NUM
dti-2638	135	3	compounds	compound	NOUN
dti-2638	135	4	(	(	PUNCT
dti-2638	135	5	g1	g1	PROPN
dti-2638	135	6	,	,	PUNCT
dti-2638	135	7	g2	g2	PROPN
dti-2638	135	8	,	,	PUNCT
dti-2638	135	9	g3	g3	PROPN
dti-2638	135	10	,	,	PUNCT
dti-2638	135	11	g5	g5	NOUN
dti-2638	135	12	,	,	PUNCT
dti-2638	135	13	g6	g6	PROPN
dti-2638	135	14	,	,	PUNCT
dti-2638	135	15	g10	g10	PROPN
dti-2638	135	16	,	,	PUNCT
dti-2638	135	17	g11	g11	PROPN
dti-2638	135	18	,	,	PUNCT
dti-2638	135	19	g14	g14	NOUN
dti-2638	135	20	,	,	PUNCT
dti-2638	135	21	g18	g18	PROPN
dti-2638	135	22	,	,	PUNCT
dti-2638	135	23	g19	g19	PROPN
dti-2638	135	24	,	,	PUNCT
dti-2638	135	25	and	and	CCONJ
dti-2638	135	26	g38	g38	NOUN
dti-2638	135	27	)	)	PUNCT
dti-2638	135	28	should	should	AUX
dti-2638	135	29	be	be	AUX
dti-2638	135	30	tested	test	VERB
dti-2638	135	31	at	at	ADP
dti-2638	135	32	still	still	ADV
dti-2638	135	33	lesser	less	ADJ
dti-2638	135	34	concentrations	concentration	NOUN
dti-2638	135	35	to	to	PART
dti-2638	135	36	find	find	VERB
dti-2638	135	37	out	out	ADP
dti-2638	135	38	minimum	minimum	ADJ
dti-2638	135	39	effective	effective	ADJ
dti-2638	135	40	concentration	concentration	NOUN
dti-2638	135	41	(	(	PUNCT
dti-2638	135	42	mec	mec	NOUN
dti-2638	135	43	)	)	PUNCT
dti-2638	135	44	.	.	PUNCT
dti-2638	136	1	eight	eight	NUM
dti-2638	136	2	of	of	ADP
dti-2638	136	3	the	the	DET
dti-2638	136	4	test	test	NOUN
dti-2638	136	5	compounds	compound	NOUN
dti-2638	136	6	were	be	AUX
dti-2638	136	7	found	find	VERB
dti-2638	136	8	to	to	PART
dti-2638	136	9	possess	possess	VERB
dti-2638	136	10	dual	dual	ADJ
dti-2638	136	11	activity	activity	NOUN
dti-2638	136	12	,	,	PUNCT
dti-2638	136	13	that	that	ADV
dti-2638	136	14	is	is	ADV
dti-2638	136	15	,	,	PUNCT
dti-2638	136	16	anti	anti	ADJ
dti-2638	136	17	-	-	ADJ
dti-2638	136	18	pathogenic	pathogenic	ADJ
dti-2638	136	19	as	as	ADV
dti-2638	136	20	well	well	ADV
dti-2638	136	21	as	as	ADP
dti-2638	136	22	anthelmintic	anthelmintic	ADJ
dti-2638	136	23	.	.	PUNCT
dti-2638	137	1	eight	eight	NUM
dti-2638	137	2	of	of	ADP
dti-2638	137	3	the	the	DET
dti-2638	137	4	active	active	ADJ
dti-2638	137	5	anti	anti	ADJ
dti-2638	137	6	-	-	ADJ
dti-2638	137	7	pseudomonas	pseudomonas	ADJ
dti-2638	137	8	compounds	compound	NOUN
dti-2638	137	9	(	(	PUNCT
dti-2638	137	10	g2	g2	PROPN
dti-2638	137	11	,	,	PUNCT
dti-2638	137	12	g5	g5	NOUN
dti-2638	137	13	,	,	PUNCT
dti-2638	137	14	g6	g6	PROPN
dti-2638	137	15	,	,	PUNCT
dti-2638	137	16	g10	g10	PROPN
dti-2638	137	17	,	,	PUNCT
dti-2638	137	18	g11	g11	PROPN
dti-2638	137	19	,	,	PUNCT
dti-2638	137	20	g14	g14	NOUN
dti-2638	137	21	,	,	PUNCT
dti-2638	137	22	g18	g18	PROPN
dti-2638	137	23	,	,	PUNCT
dti-2638	137	24	g19	g19	PROPN
dti-2638	137	25	)	)	PUNCT
dti-2638	137	26	identified	identify	VERB
dti-2638	137	27	in	in	ADP
dti-2638	137	28	this	this	DET
dti-2638	137	29	study	study	NOUN
dti-2638	137	30	were	be	AUX
dti-2638	137	31	also	also	ADV
dti-2638	137	32	toxic	toxic	ADJ
dti-2638	137	33	to	to	ADP
dti-2638	137	34	the	the	DET
dti-2638	137	35	host	host	NOUN
dti-2638	137	36	worm	worm	NOUN
dti-2638	137	37	at	at	ADP
dti-2638	137	38	concentrations	concentration	NOUN
dti-2638	137	39	employed	employ	VERB
dti-2638	137	40	.	.	PUNCT
dti-2638	138	1	hence	hence	ADV
dti-2638	138	2	,	,	PUNCT
dti-2638	138	3	they	they	PRON
dti-2638	138	4	should	should	AUX
dti-2638	138	5	be	be	AUX
dti-2638	138	6	tested	test	VERB
dti-2638	138	7	at	at	ADP
dti-2638	138	8	still	still	ADV
dti-2638	138	9	lower	low	ADJ
dti-2638	138	10	concentrations	concentration	NOUN
dti-2638	138	11	.	.	PUNCT
dti-2638	139	1	it	it	PRON
dti-2638	139	2	is	be	AUX
dti-2638	139	3	possible	possible	ADJ
dti-2638	139	4	that	that	SCONJ
dti-2638	139	5	their	their	PRON
dti-2638	139	6	lower	low	ADJ
dti-2638	139	7	concentrations	concentration	NOUN
dti-2638	139	8	may	may	AUX
dti-2638	139	9	exhibit	exhibit	VERB
dti-2638	139	10	anti	anti	ADJ
dti-2638	139	11	-	-	ADJ
dti-2638	139	12	pathogenic	pathogenic	ADJ
dti-2638	139	13	fig	fig	NOUN
dti-2638	139	14	.	.	PUNCT
dti-2638	140	1	3	3	NUM
dti-2638	140	2	pseudomonas	pseudomona	NOUN
dti-2638	140	3	aeruginosa	aeruginosa	NOUN
dti-2638	140	4	’s	’s	PART
dti-2638	140	5	virulence	virulence	NOUN
dti-2638	140	6	towards	towards	ADP
dti-2638	140	7	the	the	DET
dti-2638	140	8	host	host	NOUN
dti-2638	140	9	worm	worm	NOUN
dti-2638	140	10	gets	get	AUX
dti-2638	140	11	attenuated	attenuate	VERB
dti-2638	140	12	in	in	ADP
dti-2638	140	13	the	the	DET
dti-2638	140	14	presence	presence	NOUN
dti-2638	140	15	of	of	ADP
dti-2638	140	16	certain	certain	ADJ
dti-2638	140	17	predicted	predict	VERB
dti-2638	140	18	lasr	lasr	PROPN
dti-2638	140	19	inhibitors	inhibitor	NOUN
dti-2638	140	20	.	.	PUNCT
dti-2638	141	1	a	a	DET
dti-2638	141	2	)	)	PUNCT
dti-2638	141	3	p.	p.	NOUN
dti-2638	141	4	aeruginosa	aeruginosa	NOUN
dti-2638	141	5	could	could	AUX
dti-2638	141	6	kill	kill	VERB
dti-2638	141	7	90%±9.19	90%±9.19	NUM
dti-2638	141	8	%	%	NOUN
dti-2638	141	9	*	*	PUNCT
dti-2638	141	10	*	*	PUNCT
dti-2638	141	11	and	and	CCONJ
dti-2638	141	12	43%±5.7	43%±5.7	NUM
dti-2638	141	13	%	%	NOUN
dti-2638	141	14	*	*	PUNCT
dti-2638	142	1	*	*	PUNCT
dti-2638	142	2	*	*	PUNCT
dti-2638	142	3	lesser	less	ADJ
dti-2638	142	4	worms	worm	NOUN
dti-2638	142	5	in	in	ADP
dti-2638	142	6	the	the	DET
dti-2638	142	7	presence	presence	NOUN
dti-2638	142	8	of	of	ADP
dti-2638	142	9	g1	g1	PROPN
dti-2638	142	10	(	(	PUNCT
dti-2638	142	11	z30981775	z30981775	NOUN
dti-2638	142	12	)	)	PUNCT
dti-2638	142	13	and	and	CCONJ
dti-2638	142	14	g2	g2	PROPN
dti-2638	142	15	(	(	PUNCT
dti-2638	142	16	z65195564	z65195564	NOUN
dti-2638	142	17	)	)	PUNCT
dti-2638	142	18	,	,	PUNCT
dti-2638	142	19	respectively	respectively	ADV
dti-2638	142	20	.	.	PUNCT
dti-2638	143	1	b	b	X
dti-2638	143	2	)	)	PUNCT
dti-2638	143	3	p.	p.	NOUN
dti-2638	143	4	aeruginosa	aeruginosa	NOUN
dti-2638	143	5	could	could	AUX
dti-2638	143	6	kill	kill	VERB
dti-2638	143	7	90%±0	90%±0	NUM
dti-2638	143	8	%	%	NOUN
dti-2638	143	9	*	*	PUNCT
dti-2638	143	10	*	*	PUNCT
dti-2638	143	11	*	*	PUNCT
dti-2638	143	12	and	and	CCONJ
dti-2638	143	13	53%±5.7	53%±5.7	NUM
dti-2638	143	14	%	%	NOUN
dti-2638	143	15	*	*	PUNCT
dti-2638	143	16	*	*	PUNCT
dti-2638	143	17	*	*	PUNCT
dti-2638	143	18	lesser	less	ADJ
dti-2638	143	19	worms	worm	NOUN
dti-2638	143	20	in	in	ADP
dti-2638	143	21	the	the	DET
dti-2638	143	22	presence	presence	NOUN
dti-2638	143	23	of	of	ADP
dti-2638	143	24	g3	g3	PROPN
dti-2638	143	25	(	(	PUNCT
dti-2638	143	26	z212728858	z212728858	NOUN
dti-2638	143	27	)	)	PUNCT
dti-2638	143	28	and	and	CCONJ
dti-2638	143	29	g5	g5	NOUN
dti-2638	143	30	(	(	PUNCT
dti-2638	143	31	z354444420	z354444420	PROPN
dti-2638	143	32	)	)	PUNCT
dti-2638	143	33	,	,	PUNCT
dti-2638	143	34	respectively	respectively	ADV
dti-2638	143	35	.	.	PUNCT
dti-2638	144	1	c	c	X
dti-2638	144	2	)	)	PUNCT
dti-2638	144	3	p.	p.	NOUN
dti-2638	144	4	aeruginosa	aeruginosa	NOUN
dti-2638	144	5	could	could	AUX
dti-2638	144	6	kill	kill	VERB
dti-2638	144	7	23%±5.7	23%±5.7	NUM
dti-2638	144	8	%	%	NOUN
dti-2638	144	9	*	*	PUNCT
dti-2638	144	10	*	*	PUNCT
dti-2638	144	11	*	*	PUNCT
dti-2638	144	12	and	and	CCONJ
dti-2638	144	13	53%±5.7	53%±5.7	NUM
dti-2638	144	14	%	%	NOUN
dti-2638	144	15	*	*	PUNCT
dti-2638	144	16	*	*	PUNCT
dti-2638	144	17	*	*	PUNCT
dti-2638	144	18	lesser	less	ADJ
dti-2638	144	19	worms	worm	NOUN
dti-2638	144	20	in	in	ADP
dti-2638	144	21	the	the	DET
dti-2638	144	22	presence	presence	NOUN
dti-2638	144	23	of	of	ADP
dti-2638	144	24	g6	g6	ADJ
dti-2638	144	25	(	(	PUNCT
dti-2638	144	26	z400859658	z400859658	NOUN
dti-2638	144	27	)	)	PUNCT
dti-2638	144	28	and	and	CCONJ
dti-2638	144	29	g10	g10	PROPN
dti-2638	144	30	(	(	PUNCT
dti-2638	144	31	z1426094174	z1426094174	PROPN
dti-2638	144	32	)	)	PUNCT
dti-2638	144	33	,	,	PUNCT
dti-2638	144	34	respectively	respectively	ADV
dti-2638	144	35	.	.	PUNCT
dti-2638	145	1	d	d	X
dti-2638	145	2	)	)	PUNCT
dti-2638	145	3	p.	p.	NOUN
dti-2638	145	4	aeruginosa	aeruginosa	NOUN
dti-2638	145	5	could	could	AUX
dti-2638	145	6	kill	kill	VERB
dti-2638	145	7	43%±5.7	43%±5.7	NUM
dti-2638	145	8	%	%	NOUN
dti-2638	145	9	*	*	PUNCT
dti-2638	146	1	*	*	PUNCT
dti-2638	146	2	*	*	PUNCT
dti-2638	146	3	and	and	CCONJ
dti-2638	146	4	63%±5.7	63%±5.7	NUM
dti-2638	146	5	%	%	NOUN
dti-2638	146	6	*	*	PUNCT
dti-2638	146	7	*	*	PUNCT
dti-2638	146	8	*	*	PUNCT
dti-2638	146	9	lesser	less	ADJ
dti-2638	146	10	worms	worm	NOUN
dti-2638	146	11	in	in	ADP
dti-2638	146	12	the	the	DET
dti-2638	146	13	presence	presence	NOUN
dti-2638	146	14	of	of	ADP
dti-2638	146	15	g11	g11	X
dti-2638	146	16	(	(	PUNCT
dti-2638	146	17	z1625994950	z1625994950	PROPN
dti-2638	146	18	)	)	PUNCT
dti-2638	146	19	and	and	CCONJ
dti-2638	146	20	g14	g14	NOUN
dti-2638	146	21	(	(	PUNCT
dti-2638	146	22	z104586200	z104586200	NOUN
dti-2638	146	23	)	)	PUNCT
dti-2638	146	24	,	,	PUNCT
dti-2638	146	25	respectively	respectively	ADV
dti-2638	146	26	.	.	PUNCT
dti-2638	147	1	e	e	X
dti-2638	147	2	)	)	PUNCT
dti-2638	147	3	p.	p.	NOUN
dti-2638	147	4	aeruginosa	aeruginosa	NOUN
dti-2638	147	5	could	could	AUX
dti-2638	147	6	kill	kill	VERB
dti-2638	147	7	46%±5.7	46%±5.7	NUM
dti-2638	147	8	%	%	NOUN
dti-2638	147	9	*	*	PUNCT
dti-2638	147	10	*	*	PUNCT
dti-2638	147	11	*	*	PUNCT
dti-2638	147	12	and	and	CCONJ
dti-2638	147	13	67%±5.7	67%±5.7	NUM
dti-2638	147	14	%	%	NOUN
dti-2638	147	15	*	*	PUNCT
dti-2638	148	1	*	*	PUNCT
dti-2638	148	2	*	*	PUNCT
dti-2638	148	3	lesser	less	ADJ
dti-2638	148	4	worms	worm	NOUN
dti-2638	148	5	in	in	ADP
dti-2638	148	6	the	the	DET
dti-2638	148	7	presence	presence	NOUN
dti-2638	148	8	of	of	ADP
dti-2638	148	9	g18	g18	PROPN
dti-2638	148	10	(	(	PUNCT
dti-2638	148	11	z1084397894	z1084397894	NUM
dti-2638	148	12	)	)	PUNCT
dti-2638	148	13	and	and	CCONJ
dti-2638	148	14	g19	g19	PROPN
dti-2638	148	15	(	(	PUNCT
dti-2638	148	16	z1212781307	z1212781307	NUM
dti-2638	148	17	)	)	PUNCT
dti-2638	148	18	,	,	PUNCT
dti-2638	148	19	respectively	respectively	ADV
dti-2638	148	20	.	.	PUNCT
dti-2638	149	1	f	f	X
dti-2638	149	2	)	)	PUNCT
dti-2638	150	1	p.	p.	NOUN
dti-2638	150	2	aeruginosa	aeruginosa	NOUN
dti-2638	150	3	could	could	AUX
dti-2638	150	4	kill	kill	VERB
dti-2638	150	5	63.3%±5.7	63.3%±5.7	NUM
dti-2638	150	6	%	%	NOUN
dti-2638	150	7	*	*	PUNCT
dti-2638	151	1	*	*	PUNCT
dti-2638	151	2	*	*	PUNCT
dti-2638	151	3	and	and	CCONJ
dti-2638	151	4	100%±0	100%±0	NUM
dti-2638	151	5	%	%	NOUN
dti-2638	151	6	*	*	PUNCT
dti-2638	151	7	*	*	PUNCT
dti-2638	151	8	*	*	PUNCT
dti-2638	151	9	lesser	less	ADJ
dti-2638	151	10	worms	worm	NOUN
dti-2638	151	11	in	in	ADP
dti-2638	151	12	the	the	DET
dti-2638	151	13	presence	presence	NOUN
dti-2638	151	14	of	of	ADP
dti-2638	151	15	g38	g38	ADJ
dti-2638	151	16	(	(	PUNCT
dti-2638	151	17	z89293640	z89293640	NOUN
dti-2638	151	18	)	)	PUNCT
dti-2638	151	19	and	and	CCONJ
dti-2638	151	20	ofloxacin	ofloxacin	NOUN
dti-2638	151	21	(	(	PUNCT
dti-2638	151	22	0.5	0.5	NUM
dti-2638	151	23	µg	µg	NOUN
dti-2638	151	24	/	/	SYM
dti-2638	151	25	ml	ml	NOUN
dti-2638	151	26	)	)	PUNCT
dti-2638	151	27	,	,	PUNCT
dti-2638	151	28	respectively	respectively	ADV
dti-2638	151	29	.	.	PUNCT
dti-2638	152	1	later	later	ADV
dti-2638	152	2	it	it	PRON
dti-2638	152	3	was	be	AUX
dti-2638	152	4	employed	employ	VERB
dti-2638	152	5	as	as	ADP
dti-2638	152	6	a	a	DET
dti-2638	152	7	positive	positive	ADJ
dti-2638	152	8	control	control	NOUN
dti-2638	152	9	at	at	ADP
dti-2638	152	10	its	its	PRON
dti-2638	152	11	sub	sub	ADJ
dti-2638	152	12	-	-	ADJ
dti-2638	152	13	minimum	minimum	ADJ
dti-2638	152	14	inhibitory	inhibitory	ADJ
dti-2638	152	15	concentration	concentration	NOUN
dti-2638	152	16	(	(	PUNCT
dti-2638	152	17	mic	mic	ADJ
dti-2638	152	18	)	)	PUNCT
dti-2638	152	19	level	level	NOUN
dti-2638	152	20	,	,	PUNCT
dti-2638	152	21	and	and	CCONJ
dti-2638	152	22	it	it	PRON
dti-2638	152	23	did	do	AUX
dti-2638	152	24	allow	allow	VERB
dti-2638	152	25	progeny	progeny	ADJ
dti-2638	152	26	formation	formation	NOUN
dti-2638	152	27	in	in	ADP
dti-2638	152	28	worm	worm	NOUN
dti-2638	152	29	population	population	NOUN
dti-2638	152	30	from	from	ADP
dti-2638	152	31	the	the	DET
dti-2638	152	32	third	third	ADJ
dti-2638	152	33	day	day	NOUN
dti-2638	152	34	onwards	onwards	ADV
dti-2638	152	35	.	.	PUNCT
dti-2638	153	1	dimethyl	dimethyl	NOUN
dti-2638	153	2	sulfoxide	sulfoxide	NOUN
dti-2638	153	3	(	(	PUNCT
dti-2638	153	4	dmso	dmso	NOUN
dti-2638	153	5	;	;	PUNCT
dti-2638	153	6	0.5	0.5	NUM
dti-2638	153	7	%	%	NOUN
dti-2638	153	8	v	v	ADP
dti-2638	153	9	/	/	SYM
dti-2638	153	10	v	v	NOUN
dti-2638	153	11	)	)	PUNCT
dti-2638	153	12	present	present	ADJ
dti-2638	153	13	in	in	ADP
dti-2638	153	14	the	the	DET
dti-2638	153	15	‘	'	PUNCT
dti-2638	153	16	vehicle	vehicle	NOUN
dti-2638	153	17	control	control	NOUN
dti-2638	153	18	’	'	PUNCT
dti-2638	153	19	neither	neither	CCONJ
dti-2638	153	20	affected	affect	VERB
dti-2638	153	21	virulence	virulence	NOUN
dti-2638	153	22	of	of	ADP
dti-2638	153	23	the	the	DET
dti-2638	153	24	bacterium	bacterium	NOUN
dti-2638	153	25	towards	towards	ADP
dti-2638	153	26	caenorhabditis	caenorhabditis	ADJ
dti-2638	153	27	elegans	elegan	NOUN
dti-2638	153	28	,	,	PUNCT
dti-2638	153	29	nor	nor	CCONJ
dti-2638	153	30	did	do	AUX
dti-2638	153	31	it	it	PRON
dti-2638	153	32	show	show	VERB
dti-2638	153	33	any	any	DET
dti-2638	153	34	effect	effect	NOUN
dti-2638	153	35	on	on	ADP
dti-2638	153	36	worm	worm	NOUN
dti-2638	153	37	survival	survival	NOUN
dti-2638	153	38	.	.	PUNCT
dti-2638	154	1	*	*	PUNCT
dti-2638	154	2	*	*	PUNCT
dti-2638	154	3	p<0.01	p<0.01	PROPN
dti-2638	154	4	,	,	PUNCT
dti-2638	154	5	*	*	PUNCT
dti-2638	154	6	*	*	PUNCT
dti-2638	154	7	*	*	PUNCT
dti-2638	154	8	p<0.001	p<0.001	ADJ
dti-2638	154	9	.	.	PUNCT
dti-2638	155	1	the	the	DET
dti-2638	155	2	percent	percent	NOUN
dti-2638	155	3	values	value	NOUN
dti-2638	155	4	reported	report	VERB
dti-2638	155	5	pertain	pertain	NOUN
dti-2638	155	6	to	to	ADP
dti-2638	155	7	the	the	DET
dti-2638	155	8	worm	worm	NOUN
dti-2638	155	9	survival	survival	NOUN
dti-2638	155	10	3	3	NUM
dti-2638	155	11	days	day	NOUN
dti-2638	155	12	post	post	ADJ
dti-2638	155	13	-	-	NOUN
dti-2638	155	14	infection	infection	NOUN
dti-2638	155	15	.	.	PUNCT
dti-2638	156	1	table	table	NOUN
dti-2638	156	2	i	i	PRON
dti-2638	156	3	list	list	NOUN
dti-2638	156	4	of	of	ADP
dti-2638	156	5	predicted	predict	VERB
dti-2638	156	6	lasr	lasr	PROPN
dti-2638	156	7	inhibitors	inhibitor	NOUN
dti-2638	156	8	found	find	VERB
dti-2638	156	9	to	to	PART
dti-2638	156	10	possess	possess	VERB
dti-2638	156	11	in	in	ADP
dti-2638	156	12	vivo	vivo	ADJ
dti-2638	156	13	anti	anti	ADJ
dti-2638	156	14	-	-	ADJ
dti-2638	156	15	pseudomonas	pseudomonas	ADJ
dti-2638	156	16	aeruginosa	aeruginosa	NOUN
dti-2638	156	17	activity	activity	NOUN
dti-2638	156	18	lab	lab	NOUN
dti-2638	156	19	code	code	NOUN
dti-2638	156	20	manufacturer	manufacturer	NOUN
dti-2638	156	21	’s	’s	PART
dti-2638	156	22	code	code	NOUN
dti-2638	156	23	conc	conc	NOUN
dti-2638	156	24	.	.	PUNCT
dti-2638	157	1	(	(	PUNCT
dti-2638	157	2	µg	µg	NOUN
dti-2638	157	3	/	/	SYM
dti-2638	157	4	ml	ml	NOUN
dti-2638	157	5	)	)	PUNCT
dti-2638	157	6	%	%	NOUN
dti-2638	157	7	reduction	reduction	NOUN
dti-2638	157	8	in	in	ADP
dti-2638	157	9	bacterial	bacterial	ADJ
dti-2638	157	10	virulence	virulence	NOUN
dti-2638	157	11	3rd	3rd	ADJ
dti-2638	157	12	day	day	NOUN
dti-2638	157	13	end	end	NOUN
dti-2638	157	14	-	-	PUNCT
dti-2638	157	15	point	point	NOUN
dti-2638	157	16	5th	5th	ADJ
dti-2638	157	17	day	day	NOUN
dti-2638	157	18	end	end	NOUN
dti-2638	157	19	-	-	PUNCT
dti-2638	157	20	point	point	NOUN
dti-2638	157	21	g1	g1	NOUN
dti-2638	157	22	z30981775	z30981775	NOUN
dti-2638	157	23	25	25	NUM
dti-2638	157	24	90	90	NUM
dti-2638	157	25	±	±	NUM
dti-2638	157	26	9.19	9.19	NUM
dti-2638	157	27	*	*	NOUN
dti-2638	157	28	*	*	PROPN
dti-2638	157	29	82	82	NUM
dti-2638	157	30	±	±	NUM
dti-2638	157	31	7.07	7.07	NUM
dti-2638	157	32	*	*	PUNCT
dti-2638	157	33	*	*	PUNCT
dti-2638	157	34	*	*	PUNCT
dti-2638	157	35	g2	g2	PROPN
dti-2638	157	36	z65195564	z65195564	PROPN
dti-2638	157	37	25	25	NUM
dti-2638	157	38	43	43	NUM
dti-2638	157	39	±	±	NUM
dti-2638	157	40	5.7	5.7	NUM
dti-2638	157	41	*	*	PUNCT
dti-2638	157	42	*	*	PUNCT
dti-2638	157	43	*	*	PUNCT
dti-2638	157	44	10	10	NUM
dti-2638	157	45	±	±	NOUN
dti-2638	157	46	0	0	NUM
dti-2638	157	47	*	*	PUNCT
dti-2638	157	48	*	*	PUNCT
dti-2638	157	49	*	*	PUNCT
dti-2638	157	50	g3	g3	X
dti-2638	157	51	z212728858	z212728858	NOUN
dti-2638	157	52	25	25	NUM
dti-2638	157	53	90	90	NUM
dti-2638	157	54	±	±	NOUN
dti-2638	157	55	0	0	NUM
dti-2638	157	56	*	*	PUNCT
dti-2638	157	57	*	*	PUNCT
dti-2638	157	58	*	*	PUNCT
dti-2638	157	59	73	73	NUM
dti-2638	157	60	±	±	NUM
dti-2638	157	61	11.5	11.5	NUM
dti-2638	157	62	*	*	PUNCT
dti-2638	157	63	*	*	PUNCT
dti-2638	157	64	*	*	PUNCT
dti-2638	158	1	g5	g5	NOUN
dti-2638	158	2	z354444420	z354444420	PROPN
dti-2638	158	3	25	25	NUM
dti-2638	158	4	53	53	NUM
dti-2638	158	5	±	±	NUM
dti-2638	158	6	5.7	5.7	NUM
dti-2638	158	7	*	*	PUNCT
dti-2638	158	8	*	*	PUNCT
dti-2638	158	9	*	*	PUNCT
dti-2638	158	10	33	33	NUM
dti-2638	158	11	±	±	NUM
dti-2638	158	12	5.7	5.7	NUM
dti-2638	158	13	*	*	PUNCT
dti-2638	158	14	*	*	PUNCT
dti-2638	159	1	*	*	PUNCT
dti-2638	159	2	g6	g6	ADJ
dti-2638	159	3	z400859658	z400859658	NUM
dti-2638	159	4	25	25	NUM
dti-2638	159	5	23	23	NUM
dti-2638	159	6	±	±	NUM
dti-2638	159	7	5.7	5.7	NUM
dti-2638	159	8	*	*	PUNCT
dti-2638	159	9	*	*	PUNCT
dti-2638	159	10	*	*	PUNCT
dti-2638	159	11	3	3	NUM
dti-2638	159	12	±	±	NUM
dti-2638	159	13	5.7	5.7	NUM
dti-2638	159	14	g10	g10	PROPN
dti-2638	159	15	z1426094174	z1426094174	PROPN
dti-2638	159	16	25	25	NUM
dti-2638	159	17	53	53	NUM
dti-2638	159	18	±	±	NUM
dti-2638	159	19	5.7	5.7	NUM
dti-2638	159	20	*	*	PUNCT
dti-2638	159	21	*	*	PUNCT
dti-2638	159	22	*	*	PUNCT
dti-2638	159	23	33	33	NUM
dti-2638	159	24	±	±	NUM
dti-2638	159	25	5.7	5.7	NUM
dti-2638	159	26	*	*	PUNCT
dti-2638	159	27	*	*	PUNCT
dti-2638	159	28	*	*	PUNCT
dti-2638	159	29	g11	g11	X
dti-2638	159	30	z1625994950	z1625994950	NOUN
dti-2638	159	31	25	25	NUM
dti-2638	159	32	43	43	NUM
dti-2638	159	33	±	±	NUM
dti-2638	159	34	5.7	5.7	NUM
dti-2638	159	35	*	*	PUNCT
dti-2638	159	36	*	*	PUNCT
dti-2638	159	37	*	*	PUNCT
dti-2638	159	38	6	6	NUM
dti-2638	159	39	±	±	NUM
dti-2638	159	40	11.5	11.5	NUM
dti-2638	159	41	g14	g14	NOUN
dti-2638	159	42	z104586200	z104586200	PROPN
dti-2638	159	43	25	25	NUM
dti-2638	159	44	63	63	NUM
dti-2638	159	45	±	±	NUM
dti-2638	159	46	5.7	5.7	NUM
dti-2638	159	47	*	*	PUNCT
dti-2638	159	48	*	*	PUNCT
dti-2638	159	49	*	*	PUNCT
dti-2638	159	50	23	23	NUM
dti-2638	159	51	±	±	NUM
dti-2638	159	52	5.7	5.7	NUM
dti-2638	159	53	*	*	PUNCT
dti-2638	159	54	*	*	PUNCT
dti-2638	159	55	*	*	PROPN
dti-2638	159	56	g18	g18	PROPN
dti-2638	159	57	z1084397894	z1084397894	PROPN
dti-2638	159	58	25	25	NUM
dti-2638	159	59	46	46	NUM
dti-2638	159	60	±	±	NUM
dti-2638	159	61	5.7	5.7	NUM
dti-2638	159	62	*	*	PUNCT
dti-2638	159	63	*	*	PUNCT
dti-2638	159	64	*	*	PUNCT
dti-2638	159	65	16	16	NUM
dti-2638	159	66	±	±	NUM
dti-2638	159	67	5.7	5.7	NUM
dti-2638	159	68	*	*	PUNCT
dti-2638	159	69	*	*	PUNCT
dti-2638	159	70	g19	g19	PROPN
dti-2638	159	71	z1212781307	z1212781307	NUM
dti-2638	159	72	25	25	NUM
dti-2638	159	73	67	67	NUM
dti-2638	159	74	±	±	NUM
dti-2638	159	75	5.7	5.7	NUM
dti-2638	159	76	*	*	PUNCT
dti-2638	159	77	*	*	PUNCT
dti-2638	159	78	*	*	PUNCT
dti-2638	159	79	26	26	NUM
dti-2638	159	80	±	±	NUM
dti-2638	159	81	11.5	11.5	NUM
dti-2638	159	82	*	*	NOUN
dti-2638	159	83	*	*	NOUN
dti-2638	159	84	g38	g38	NOUN
dti-2638	159	85	z89293640	z89293640	NUM
dti-2638	159	86	50	50	NUM
dti-2638	159	87	63.3	63.3	NUM
dti-2638	159	88	±	±	NUM
dti-2638	159	89	5.7	5.7	NUM
dti-2638	159	90	*	*	PUNCT
dti-2638	159	91	*	*	PUNCT
dti-2638	159	92	*	*	PUNCT
dti-2638	159	93	6	6	NUM
dti-2638	159	94	±	±	NUM
dti-2638	159	95	5.7	5.7	NUM
dti-2638	159	96	*	*	PUNCT
dti-2638	159	97	*	*	PUNCT
dti-2638	159	98	p<0.01	p<0.01	PROPN
dti-2638	159	99	,	,	PUNCT
dti-2638	159	100	*	*	PUNCT
dti-2638	159	101	*	*	PUNCT
dti-2638	159	102	*	*	PUNCT
dti-2638	159	103	p<0.001	p<0.001	ADJ
dti-2638	159	104	.	.	PUNCT
dti-2638	160	1	small	small	ADJ
dti-2638	160	2	-	-	PUNCT
dti-2638	160	3	molecule	molecule	NOUN
dti-2638	160	4	inhibitors	inhibitor	NOUN
dti-2638	160	5	of	of	ADP
dti-2638	160	6	pseudomonas	pseudomona	NOUN
dti-2638	160	7	aeruginosa	aeruginosa	NOUN
dti-2638	160	8	lasr	lasr	PROPN
dti-2638	160	9	or	or	CCONJ
dti-2638	160	10	nor106	nor106	NOUN
dti-2638	160	11	©	©	PROPN
dti-2638	160	12	2023	2023	NUM
dti-2638	160	13	the	the	DET
dti-2638	160	14	authors	author	NOUN
dti-2638	160	15	.	.	PUNCT
dti-2638	161	1	drug	drug	NOUN
dti-2638	161	2	target	target	NOUN
dti-2638	161	3	insights	insight	NOUN
dti-2638	161	4	issn	issn	VERB
dti-2638	161	5	1177	1177	NUM
dti-2638	161	6	-	-	SYM
dti-2638	161	7	3928	3928	NUM
dti-2638	161	8	www.aboutscience.eu/dti	www.aboutscience.eu/dti	NOUN
dti-2638	161	9	activity	activity	NOUN
dti-2638	161	10	without	without	ADP
dti-2638	161	11	exerting	exert	VERB
dti-2638	161	12	any	any	DET
dti-2638	161	13	toxicity	toxicity	NOUN
dti-2638	161	14	towards	towards	ADP
dti-2638	161	15	the	the	DET
dti-2638	161	16	eukaryotic	eukaryotic	ADJ
dti-2638	161	17	host	host	NOUN
dti-2638	161	18	.	.	PUNCT
dti-2638	162	1	masking	mask	VERB
dti-2638	162	2	of	of	ADP
dti-2638	162	3	the	the	DET
dti-2638	162	4	anti	anti	ADJ
dti-2638	162	5	-	-	ADJ
dti-2638	162	6	pathogenic	pathogenic	ADJ
dti-2638	162	7	activity	activity	NOUN
dti-2638	162	8	by	by	ADP
dti-2638	162	9	antiworm	antiworm	ADJ
dti-2638	162	10	activity	activity	NOUN
dti-2638	162	11	of	of	ADP
dti-2638	162	12	the	the	DET
dti-2638	162	13	same	same	ADJ
dti-2638	162	14	compound	compound	NOUN
dti-2638	162	15	(	(	PUNCT
dti-2638	162	16	tab	tab	PROPN
dti-2638	162	17	.	.	PUNCT
dti-2638	162	18	ii	ii	PROPN
dti-2638	162	19	)	)	PUNCT
dti-2638	162	20	needs	need	VERB
dti-2638	162	21	to	to	PART
dti-2638	162	22	be	be	AUX
dti-2638	162	23	paid	pay	VERB
dti-2638	162	24	attention	attention	NOUN
dti-2638	162	25	while	while	SCONJ
dti-2638	162	26	interpreting	interpret	VERB
dti-2638	162	27	the	the	DET
dti-2638	162	28	results	result	NOUN
dti-2638	162	29	.	.	PUNCT
dti-2638	163	1	compounds	compound	NOUN
dti-2638	163	2	found	find	VERB
dti-2638	163	3	to	to	PART
dti-2638	163	4	possess	possess	VERB
dti-2638	163	5	anti	anti	ADJ
dti-2638	163	6	-	-	ADJ
dti-2638	163	7	pathogenic	pathogenic	ADJ
dti-2638	163	8	activity	activity	NOUN
dti-2638	163	9	in	in	ADP
dti-2638	163	10	our	our	PRON
dti-2638	163	11	study	study	NOUN
dti-2638	163	12	were	be	AUX
dti-2638	163	13	effective	effective	ADJ
dti-2638	163	14	at	at	ADP
dti-2638	163	15	25	25	NUM
dti-2638	163	16	-	-	SYM
dti-2638	163	17	50	50	NUM
dti-2638	163	18	ppm	ppm	NOUN
dti-2638	163	19	,	,	PUNCT
dti-2638	163	20	which	which	PRON
dti-2638	163	21	seems	seem	VERB
dti-2638	163	22	to	to	PART
dti-2638	163	23	be	be	AUX
dti-2638	163	24	good	good	ADJ
dti-2638	163	25	enough	enough	ADV
dti-2638	163	26	to	to	PART
dti-2638	163	27	warrant	warrant	VERB
dti-2638	163	28	further	further	ADJ
dti-2638	163	29	investigation	investigation	NOUN
dti-2638	163	30	,	,	PUNCT
dti-2638	163	31	while	while	SCONJ
dti-2638	163	32	comparing	compare	VERB
dti-2638	163	33	with	with	ADP
dti-2638	163	34	effective	effective	ADJ
dti-2638	163	35	concentrations	concentration	NOUN
dti-2638	163	36	reported	report	VERB
dti-2638	163	37	for	for	ADP
dti-2638	163	38	other	other	ADJ
dti-2638	163	39	lasr	lasr	PROPN
dti-2638	163	40	inhibitors	inhibitor	NOUN
dti-2638	163	41	.	.	PUNCT
dti-2638	164	1	for	for	ADP
dti-2638	164	2	example	example	NOUN
dti-2638	164	3	,	,	PUNCT
dti-2638	164	4	a	a	DET
dti-2638	164	5	potent	potent	ADJ
dti-2638	164	6	lasr	lasr	NOUN
dti-2638	164	7	inhibitor	inhibitor	NOUN
dti-2638	164	8	,	,	PUNCT
dti-2638	164	9	lasr	lasr	PROPN
dti-2638	164	10	-	-	PUNCT
dti-2638	164	11	in-4	in-4	PROPN
dti-2638	164	12	,	,	PUNCT
dti-2638	164	13	was	be	AUX
dti-2638	164	14	shown	show	VERB
dti-2638	164	15	to	to	PART
dti-2638	164	16	possess	possess	VERB
dti-2638	164	17	inhibitory	inhibitory	ADJ
dti-2638	164	18	activity	activity	NOUN
dti-2638	164	19	against	against	ADP
dti-2638	164	20	p.	p.	NOUN
dti-2638	164	21	aeruginosa	aeruginosa	PROPN
dti-2638	164	22	with	with	ADP
dti-2638	164	23	mic	mic	NOUN
dti-2638	164	24	of	of	ADP
dti-2638	164	25	56.25	56.25	NUM
dti-2638	164	26	μg	μg	NOUN
dti-2638	164	27	/	/	SYM
dti-2638	164	28	ml	ml	PROPN
dti-2638	164	29	(	(	PUNCT
dti-2638	164	30	39	39	NUM
dti-2638	164	31	)	)	PUNCT
dti-2638	164	32	.	.	PUNCT
dti-2638	165	1	another	another	DET
dti-2638	165	2	lasr	lasr	PROPN
dti-2638	165	3	inhibitor	inhibitor	NOUN
dti-2638	165	4	,	,	PUNCT
dti-2638	165	5	naringenin	naringenin	PROPN
dti-2638	165	6	,	,	PUNCT
dti-2638	165	7	was	be	AUX
dti-2638	165	8	reported	report	VERB
dti-2638	165	9	to	to	PART
dti-2638	165	10	inhibit	inhibit	VERB
dti-2638	165	11	qs	qs	ADP
dti-2638	165	12	response	response	NOUN
dti-2638	165	13	in	in	ADP
dti-2638	165	14	p.	p.	NOUN
dti-2638	165	15	aeruginosa	aeruginosa	NOUN
dti-2638	165	16	by	by	ADP
dti-2638	165	17	competing	compete	VERB
dti-2638	165	18	with	with	ADP
dti-2638	165	19	n-(3	n-(3	NOUN
dti-2638	165	20	-	-	PUNCT
dti-2638	165	21	oxo	oxo	NOUN
dti-2638	165	22	-	-	PUNCT
dti-2638	165	23	dodecanoyl)-l	dodecanoyl)-l	NOUN
dti-2638	165	24	-	-	PUNCT
dti-2638	165	25	homoserine	homoserine	NOUN
dti-2638	165	26	lactone	lactone	NOUN
dti-2638	165	27	for	for	ADP
dti-2638	165	28	lasr	lasr	PROPN
dti-2638	165	29	binding	bind	VERB
dti-2638	165	30	at	at	ADP
dti-2638	165	31	136	136	NUM
dti-2638	165	32	µg	µg	NOUN
dti-2638	165	33	/	/	SYM
dti-2638	165	34	ml	ml	NOUN
dti-2638	165	35	(	(	PUNCT
dti-2638	165	36	40	40	NUM
dti-2638	165	37	)	)	PUNCT
dti-2638	165	38	.	.	PUNCT
dti-2638	166	1	o’brien	o’brien	PROPN
dti-2638	166	2	et	et	PROPN
dti-2638	166	3	al	al	PROPN
dti-2638	166	4	(	(	PUNCT
dti-2638	166	5	41	41	NUM
dti-2638	166	6	)	)	PUNCT
dti-2638	166	7	reported	report	VERB
dti-2638	166	8	br	br	PROPN
dti-2638	166	9	-	-	PUNCT
dti-2638	166	10	hsl	hsl	NOUN
dti-2638	166	11	to	to	PART
dti-2638	166	12	antagonize	antagonize	VERB
dti-2638	166	13	lasr	lasr	PROPN
dti-2638	166	14	with	with	ADP
dti-2638	166	15	ic50	ic50	PROPN
dti-2638	166	16	of	of	ADP
dti-2638	166	17	5	5	NUM
dti-2638	166	18	μg	μg	NOUN
dti-2638	166	19	/	/	SYM
dti-2638	166	20	ml	ml	NOUN
dti-2638	166	21	.	.	PUNCT
dti-2638	166	22	further	far	ADV
dti-2638	166	23	,	,	PUNCT
dti-2638	166	24	in	in	ADP
dti-2638	166	25	vitro	vitro	X
dti-2638	166	26	incubation	incubation	NOUN
dti-2638	166	27	of	of	ADP
dti-2638	166	28	bacteria	bacteria	NOUN
dti-2638	166	29	with	with	ADP
dti-2638	166	30	the	the	DET
dti-2638	166	31	compounds	compound	NOUN
dti-2638	166	32	identified	identify	VERB
dti-2638	166	33	in	in	ADP
dti-2638	166	34	this	this	DET
dti-2638	166	35	study	study	NOUN
dti-2638	166	36	to	to	PART
dti-2638	166	37	possess	possess	VERB
dti-2638	166	38	anti	anti	ADJ
dti-2638	166	39	-	-	ADJ
dti-2638	166	40	p.	p.	ADJ
dti-2638	166	41	aeruginosa	aeruginosa	NOUN
dti-2638	166	42	activity	activity	NOUN
dti-2638	166	43	is	be	AUX
dti-2638	166	44	required	require	VERB
dti-2638	166	45	to	to	PART
dti-2638	166	46	find	find	VERB
dti-2638	166	47	out	out	ADP
dti-2638	166	48	whether	whether	SCONJ
dti-2638	166	49	these	these	DET
dti-2638	166	50	compounds	compound	NOUN
dti-2638	166	51	exhibit	exhibit	VERB
dti-2638	166	52	bactericidal	bactericidal	ADJ
dti-2638	166	53	/	/	SYM
dti-2638	166	54	bacteriostatic	bacteriostatic	ADJ
dti-2638	166	55	/	/	SYM
dti-2638	166	56	anti	anti	ADJ
dti-2638	166	57	-	-	ADJ
dti-2638	166	58	virulence	virulence	ADJ
dti-2638	166	59	activity	activity	NOUN
dti-2638	166	60	.	.	PUNCT
dti-2638	167	1	while	while	SCONJ
dti-2638	167	2	evaluating	evaluate	VERB
dti-2638	167	3	any	any	DET
dti-2638	167	4	compound(s	compound(s	NOUN
dti-2638	167	5	)	)	PUNCT
dti-2638	167	6	for	for	ADP
dti-2638	167	7	their	their	PRON
dti-2638	167	8	anti	anti	ADJ
dti-2638	167	9	-	-	ADJ
dti-2638	167	10	virulence	virulence	ADJ
dti-2638	167	11	activity	activity	NOUN
dti-2638	167	12	,	,	PUNCT
dti-2638	167	13	it	it	PRON
dti-2638	167	14	should	should	AUX
dti-2638	167	15	be	be	AUX
dti-2638	167	16	kept	keep	VERB
dti-2638	167	17	in	in	ADP
dti-2638	167	18	mind	mind	NOUN
dti-2638	167	19	that	that	SCONJ
dti-2638	167	20	even	even	ADV
dti-2638	167	21	compounds	compound	VERB
dti-2638	167	22	capable	capable	ADJ
dti-2638	167	23	of	of	ADP
dti-2638	167	24	curbing	curb	VERB
dti-2638	167	25	bacterial	bacterial	ADJ
dti-2638	167	26	virulence	virulence	NOUN
dti-2638	167	27	partially	partially	ADV
dti-2638	167	28	can	can	AUX
dti-2638	167	29	be	be	AUX
dti-2638	167	30	potentially	potentially	ADV
dti-2638	167	31	useful	useful	ADJ
dti-2638	167	32	in	in	ADP
dti-2638	167	33	combination	combination	NOUN
dti-2638	167	34	with	with	ADP
dti-2638	167	35	conventional	conventional	ADJ
dti-2638	167	36	antibiotics	antibiotic	NOUN
dti-2638	167	37	.	.	PUNCT
dti-2638	168	1	such	such	ADJ
dti-2638	168	2	compounds	compound	NOUN
dti-2638	168	3	may	may	AUX
dti-2638	168	4	be	be	AUX
dti-2638	168	5	potential	potential	ADJ
dti-2638	168	6	resistance	resistance	NOUN
dti-2638	168	7	modifiers	modifier	NOUN
dti-2638	168	8	.	.	PUNCT
dti-2638	169	1	even	even	ADV
dti-2638	169	2	as	as	ADP
dti-2638	169	3	a	a	DET
dti-2638	169	4	standalone	standalone	NOUN
dti-2638	169	5	therapy	therapy	NOUN
dti-2638	169	6	,	,	PUNCT
dti-2638	169	7	they	they	PRON
dti-2638	169	8	may	may	AUX
dti-2638	169	9	be	be	AUX
dti-2638	169	10	of	of	ADP
dti-2638	169	11	indirect	indirect	ADJ
dti-2638	169	12	help	help	NOUN
dti-2638	169	13	to	to	PART
dti-2638	169	14	host	host	VERB
dti-2638	169	15	immune	immune	ADJ
dti-2638	169	16	system	system	NOUN
dti-2638	169	17	by	by	ADP
dti-2638	169	18	reducing	reduce	VERB
dti-2638	169	19	the	the	DET
dti-2638	169	20	overall	overall	ADJ
dti-2638	169	21	bacterial	bacterial	ADJ
dti-2638	169	22	load	load	NOUN
dti-2638	169	23	to	to	PART
dti-2638	169	24	be	be	AUX
dti-2638	169	25	cleared	clear	VERB
dti-2638	169	26	by	by	ADP
dti-2638	169	27	the	the	DET
dti-2638	169	28	immune	immune	ADJ
dti-2638	169	29	system	system	NOUN
dti-2638	169	30	(	(	PUNCT
dti-2638	169	31	42,43	42,43	NOUN
dti-2638	169	32	)	)	PUNCT
dti-2638	169	33	.	.	PUNCT
dti-2638	170	1	three	three	NUM
dti-2638	170	2	of	of	ADP
dti-2638	170	3	these	these	DET
dti-2638	170	4	anti	anti	ADJ
dti-2638	170	5	-	-	ADJ
dti-2638	170	6	pathogenic	pathogenic	ADJ
dti-2638	170	7	compounds	compound	NOUN
dti-2638	170	8	(	(	PUNCT
dti-2638	170	9	g1	g1	PROPN
dti-2638	170	10	,	,	PUNCT
dti-2638	170	11	g3	g3	NOUN
dti-2638	170	12	,	,	PUNCT
dti-2638	170	13	g38	g38	NOUN
dti-2638	170	14	)	)	PUNCT
dti-2638	170	15	did	do	AUX
dti-2638	170	16	not	not	PART
dti-2638	170	17	exhibit	exhibit	VERB
dti-2638	170	18	any	any	DET
dti-2638	170	19	notable	notable	ADJ
dti-2638	170	20	toxicity	toxicity	NOUN
dti-2638	170	21	towards	towards	ADP
dti-2638	170	22	the	the	DET
dti-2638	170	23	host	host	NOUN
dti-2638	170	24	worm	worm	NOUN
dti-2638	170	25	,	,	PUNCT
dti-2638	170	26	and	and	CCONJ
dti-2638	170	27	hence	hence	ADV
dti-2638	170	28	seem	seem	VERB
dti-2638	170	29	to	to	PART
dti-2638	170	30	be	be	AUX
dti-2638	170	31	the	the	DET
dti-2638	170	32	most	most	ADV
dti-2638	170	33	logical	logical	ADJ
dti-2638	170	34	candidates	candidate	NOUN
dti-2638	170	35	for	for	ADP
dti-2638	170	36	further	further	ADJ
dti-2638	170	37	investigation	investigation	NOUN
dti-2638	170	38	.	.	PUNCT
dti-2638	171	1	these	these	DET
dti-2638	171	2	compounds	compound	NOUN
dti-2638	171	3	should	should	AUX
dti-2638	171	4	be	be	AUX
dti-2638	171	5	tested	test	VERB
dti-2638	171	6	against	against	ADP
dti-2638	171	7	multiple	multiple	ADJ
dti-2638	171	8	species	specie	NOUN
dti-2638	171	9	of	of	ADP
dti-2638	171	10	antibiotic	antibiotic	ADJ
dti-2638	171	11	-	-	PUNCT
dti-2638	171	12	resistant	resistant	ADJ
dti-2638	171	13	bacteria	bacteria	NOUN
dti-2638	171	14	to	to	PART
dti-2638	171	15	know	know	VERB
dti-2638	171	16	whether	whether	SCONJ
dti-2638	171	17	they	they	PRON
dti-2638	171	18	are	be	AUX
dti-2638	171	19	broad	broad	ADJ
dti-2638	171	20	-	-	PUNCT
dti-2638	171	21	spectrum	spectrum	NOUN
dti-2638	171	22	antimicrobials	antimicrobial	NOUN
dti-2638	171	23	.	.	PUNCT
dti-2638	172	1	additionally	additionally	ADV
dti-2638	172	2	,	,	PUNCT
dti-2638	172	3	their	their	PRON
dti-2638	172	4	effect	effect	NOUN
dti-2638	172	5	on	on	ADP
dti-2638	172	6	bacterial	bacterial	ADJ
dti-2638	172	7	gene	gene	NOUN
dti-2638	172	8	expression	expression	NOUN
dti-2638	172	9	at	at	ADP
dti-2638	172	10	whole	whole	ADJ
dti-2638	172	11	transcriptome	transcriptome	ADJ
dti-2638	172	12	level	level	NOUN
dti-2638	172	13	should	should	AUX
dti-2638	172	14	also	also	ADV
dti-2638	172	15	be	be	AUX
dti-2638	172	16	investigated	investigate	VERB
dti-2638	172	17	to	to	PART
dti-2638	172	18	elucidate	elucidate	VERB
dti-2638	172	19	the	the	DET
dti-2638	172	20	underlying	underlying	ADJ
dti-2638	172	21	molecular	molecular	ADJ
dti-2638	172	22	mechanisms	mechanism	NOUN
dti-2638	172	23	.	.	PUNCT
dti-2638	173	1	anti	anti	ADJ
dti-2638	173	2	-	-	ADJ
dti-2638	173	3	pathogenic	pathogenic	ADJ
dti-2638	173	4	activity	activity	NOUN
dti-2638	173	5	of	of	ADP
dti-2638	173	6	potential	potential	NOUN
dti-2638	173	7	nor	nor	CCONJ
dti-2638	173	8	inhibitors	inhibitor	NOUN
dti-2638	173	9	of	of	ADP
dti-2638	173	10	the	the	DET
dti-2638	173	11	total	total	ADJ
dti-2638	173	12	85	85	NUM
dti-2638	173	13	compounds	compound	NOUN
dti-2638	173	14	received	receive	VERB
dti-2638	173	15	,	,	PUNCT
dti-2638	173	16	10	10	NUM
dti-2638	173	17	were	be	AUX
dti-2638	173	18	insoluble	insoluble	ADJ
dti-2638	173	19	in	in	ADP
dti-2638	173	20	the	the	DET
dti-2638	173	21	vehicle	vehicle	NOUN
dti-2638	173	22	solvent	solvent	NOUN
dti-2638	173	23	dmso	dmso	NOUN
dti-2638	173	24	.	.	PUNCT
dti-2638	174	1	remaining	remain	VERB
dti-2638	174	2	75	75	NUM
dti-2638	174	3	compounds	compound	NOUN
dti-2638	174	4	were	be	AUX
dti-2638	174	5	assayed	assayed	ADJ
dti-2638	174	6	for	for	ADP
dti-2638	174	7	their	their	PRON
dti-2638	174	8	possible	possible	ADJ
dti-2638	174	9	anti	anti	ADJ
dti-2638	174	10	-	-	ADJ
dti-2638	174	11	pathogenic	pathogenic	ADJ
dti-2638	174	12	activity	activity	NOUN
dti-2638	174	13	by	by	ADP
dti-2638	174	14	challenging	challenge	VERB
dti-2638	174	15	the	the	DET
dti-2638	174	16	host	host	NOUN
dti-2638	174	17	worm	worm	NOUN
dti-2638	174	18	with	with	ADP
dti-2638	174	19	p.	p.	NOUN
dti-2638	174	20	aeruginosa	aeruginosa	PROPN
dti-2638	174	21	in	in	ADP
dti-2638	174	22	the	the	DET
dti-2638	174	23	presence	presence	NOUN
dti-2638	174	24	or	or	CCONJ
dti-2638	174	25	absence	absence	NOUN
dti-2638	174	26	of	of	ADP
dti-2638	174	27	test	test	NOUN
dti-2638	174	28	compounds	compound	NOUN
dti-2638	174	29	.	.	PUNCT
dti-2638	175	1	eight	eight	NUM
dti-2638	175	2	(	(	PUNCT
dti-2638	175	3	~11	~11	NOUN
dti-2638	175	4	%	%	NOUN
dti-2638	175	5	of	of	ADP
dti-2638	175	6	all	all	DET
dti-2638	175	7	the	the	DET
dti-2638	175	8	compounds	compound	NOUN
dti-2638	175	9	tested	test	VERB
dti-2638	175	10	)	)	PUNCT
dti-2638	175	11	of	of	ADP
dti-2638	175	12	the	the	DET
dti-2638	175	13	test	test	NOUN
dti-2638	175	14	compounds	compound	NOUN
dti-2638	175	15	were	be	AUX
dti-2638	175	16	able	able	ADJ
dti-2638	175	17	to	to	PART
dti-2638	175	18	rescue	rescue	VERB
dti-2638	175	19	the	the	DET
dti-2638	175	20	worm	worm	NOUN
dti-2638	175	21	population	population	NOUN
dti-2638	175	22	from	from	ADP
dti-2638	175	23	the	the	DET
dti-2638	175	24	pathogen	pathogen	NOUN
dti-2638	175	25	induced	induce	VERB
dti-2638	175	26	death	death	NOUN
dti-2638	175	27	by	by	ADP
dti-2638	175	28	40%-85	40%-85	NUM
dti-2638	175	29	%	%	NOUN
dti-2638	175	30	(	(	PUNCT
dti-2638	175	31	second	second	ADJ
dti-2638	175	32	-	-	PUNCT
dti-2638	175	33	day	day	NOUN
dti-2638	175	34	end	end	NOUN
dti-2638	175	35	-	-	PUNCT
dti-2638	175	36	point	point	NOUN
dti-2638	175	37	)	)	PUNCT
dti-2638	175	38	(	(	PUNCT
dti-2638	175	39	fig	fig	NOUN
dti-2638	175	40	.	.	PUNCT
dti-2638	176	1	4	4	NUM
dti-2638	176	2	;	;	PUNCT
dti-2638	176	3	tab	tab	PROPN
dti-2638	176	4	.	.	PUNCT
dti-2638	176	5	iii	iii	PROPN
dti-2638	176	6	)	)	PUNCT
dti-2638	176	7	.	.	PUNCT
dti-2638	177	1	five	five	NUM
dti-2638	177	2	of	of	ADP
dti-2638	177	3	the	the	DET
dti-2638	177	4	test	test	NOUN
dti-2638	177	5	compounds	compound	NOUN
dti-2638	177	6	were	be	AUX
dti-2638	177	7	found	find	VERB
dti-2638	177	8	to	to	PART
dti-2638	177	9	possess	possess	VERB
dti-2638	177	10	dual	dual	ADJ
dti-2638	177	11	activity	activity	NOUN
dti-2638	177	12	,	,	PUNCT
dti-2638	177	13	that	that	ADV
dti-2638	177	14	is	is	ADV
dti-2638	177	15	,	,	PUNCT
dti-2638	177	16	anti	anti	ADJ
dti-2638	177	17	-	-	ADJ
dti-2638	177	18	pathogenic	pathogenic	ADJ
dti-2638	177	19	as	as	ADV
dti-2638	177	20	well	well	ADV
dti-2638	177	21	as	as	ADP
dti-2638	177	22	anthelmintic	anthelmintic	ADJ
dti-2638	177	23	.	.	PUNCT
dti-2638	178	1	five	five	NUM
dti-2638	178	2	of	of	ADP
dti-2638	178	3	the	the	DET
dti-2638	178	4	active	active	ADJ
dti-2638	178	5	anti	anti	ADJ
dti-2638	178	6	-	-	ADJ
dti-2638	178	7	pseudomonas	pseudomonas	ADJ
dti-2638	178	8	compounds	compound	NOUN
dti-2638	178	9	(	(	PUNCT
dti-2638	178	10	n4	n4	PROPN
dti-2638	178	11	,	,	PUNCT
dti-2638	178	12	n36	n36	NOUN
dti-2638	178	13	,	,	PUNCT
dti-2638	178	14	n37	n37	NOUN
dti-2638	178	15	,	,	PUNCT
dti-2638	178	16	n61	n61	PROPN
dti-2638	178	17	,	,	PUNCT
dti-2638	178	18	n65	n65	NOUN
dti-2638	178	19	)	)	PUNCT
dti-2638	178	20	identified	identify	VERB
dti-2638	178	21	in	in	ADP
dti-2638	178	22	this	this	DET
dti-2638	178	23	study	study	NOUN
dti-2638	178	24	were	be	AUX
dti-2638	178	25	also	also	ADV
dti-2638	178	26	toxic	toxic	ADJ
dti-2638	178	27	to	to	ADP
dti-2638	178	28	the	the	DET
dti-2638	178	29	host	host	NOUN
dti-2638	178	30	worm	worm	NOUN
dti-2638	178	31	at	at	ADP
dti-2638	178	32	concentrations	concentration	NOUN
dti-2638	178	33	employed	employ	VERB
dti-2638	178	34	.	.	PUNCT
dti-2638	179	1	hence	hence	ADV
dti-2638	179	2	,	,	PUNCT
dti-2638	179	3	they	they	PRON
dti-2638	179	4	(	(	PUNCT
dti-2638	179	5	excluding	exclude	VERB
dti-2638	179	6	n61	n61	NOUN
dti-2638	179	7	)	)	PUNCT
dti-2638	179	8	should	should	AUX
dti-2638	179	9	be	be	AUX
dti-2638	179	10	tested	test	VERB
dti-2638	179	11	at	at	ADP
dti-2638	179	12	still	still	ADV
dti-2638	179	13	lower	low	ADJ
dti-2638	179	14	concentrations	concentration	NOUN
dti-2638	179	15	.	.	PUNCT
dti-2638	180	1	it	it	PRON
dti-2638	180	2	is	be	AUX
dti-2638	180	3	possible	possible	ADJ
dti-2638	180	4	that	that	SCONJ
dti-2638	180	5	their	their	PRON
dti-2638	180	6	lower	low	ADJ
dti-2638	180	7	concentrations	concentration	NOUN
dti-2638	180	8	may	may	AUX
dti-2638	180	9	exhibit	exhibit	VERB
dti-2638	180	10	antipathogenic	antipathogenic	ADJ
dti-2638	180	11	activity	activity	NOUN
dti-2638	180	12	without	without	ADP
dti-2638	180	13	exerting	exert	VERB
dti-2638	180	14	any	any	DET
dti-2638	180	15	toxicity	toxicity	NOUN
dti-2638	180	16	towards	towards	ADP
dti-2638	180	17	the	the	DET
dti-2638	180	18	eukaryotic	eukaryotic	ADJ
dti-2638	180	19	host	host	NOUN
dti-2638	180	20	.	.	PUNCT
dti-2638	181	1	masking	mask	VERB
dti-2638	181	2	of	of	ADP
dti-2638	181	3	the	the	DET
dti-2638	181	4	anti	anti	ADJ
dti-2638	181	5	-	-	ADJ
dti-2638	181	6	pathogenic	pathogenic	ADJ
dti-2638	181	7	activity	activity	NOUN
dti-2638	181	8	by	by	ADP
dti-2638	181	9	anti	anti	ADJ
dti-2638	181	10	-	-	ADJ
dti-2638	181	11	worm	worm	ADJ
dti-2638	181	12	activity	activity	NOUN
dti-2638	181	13	of	of	ADP
dti-2638	181	14	the	the	DET
dti-2638	181	15	same	same	ADJ
dti-2638	181	16	compound	compound	NOUN
dti-2638	181	17	(	(	PUNCT
dti-2638	181	18	tab	tab	NOUN
dti-2638	181	19	.	.	PUNCT
dti-2638	182	1	iv	iv	X
dti-2638	182	2	)	)	PUNCT
dti-2638	182	3	needs	need	VERB
dti-2638	182	4	to	to	PART
dti-2638	182	5	be	be	AUX
dti-2638	182	6	paid	pay	VERB
dti-2638	182	7	attention	attention	NOUN
dti-2638	182	8	while	while	SCONJ
dti-2638	182	9	interpreting	interpret	VERB
dti-2638	182	10	the	the	DET
dti-2638	182	11	results	result	NOUN
dti-2638	182	12	.	.	PUNCT
dti-2638	183	1	conclusion	conclusion	NOUN
dti-2638	183	2	this	this	DET
dti-2638	183	3	study	study	NOUN
dti-2638	183	4	is	be	AUX
dti-2638	183	5	a	a	DET
dti-2638	183	6	preliminary	preliminary	ADJ
dti-2638	183	7	demonstration	demonstration	NOUN
dti-2638	183	8	of	of	ADP
dti-2638	183	9	the	the	DET
dti-2638	183	10	utility	utility	NOUN
dti-2638	183	11	of	of	ADP
dti-2638	183	12	virtual	virtual	ADJ
dti-2638	183	13	screening	screening	NOUN
dti-2638	183	14	approach	approach	NOUN
dti-2638	183	15	for	for	ADP
dti-2638	183	16	discovery	discovery	NOUN
dti-2638	183	17	of	of	ADP
dti-2638	183	18	potentially	potentially	ADV
dti-2638	183	19	novel	novel	ADJ
dti-2638	183	20	anti	anti	ADJ
dti-2638	183	21	-	-	ADJ
dti-2638	183	22	pathogenic	pathogenic	ADJ
dti-2638	183	23	agents	agent	NOUN
dti-2638	183	24	.	.	PUNCT
dti-2638	184	1	virtual	virtual	ADJ
dti-2638	184	2	screening	screening	NOUN
dti-2638	184	3	can	can	AUX
dti-2638	184	4	reduce	reduce	VERB
dti-2638	184	5	the	the	DET
dti-2638	184	6	number	number	NOUN
dti-2638	184	7	of	of	ADP
dti-2638	184	8	compounds	compound	NOUN
dti-2638	184	9	required	require	VERB
dti-2638	184	10	to	to	PART
dti-2638	184	11	be	be	AUX
dti-2638	184	12	actually	actually	ADV
dti-2638	184	13	subjected	subject	VERB
dti-2638	184	14	to	to	ADP
dti-2638	184	15	wet	wet	ADJ
dti-2638	184	16	-	-	PUNCT
dti-2638	184	17	lab	lab	NOUN
dti-2638	184	18	assays	assay	NOUN
dti-2638	184	19	,	,	PUNCT
dti-2638	184	20	and	and	CCONJ
dti-2638	184	21	thus	thus	ADV
dti-2638	184	22	reducing	reduce	VERB
dti-2638	184	23	the	the	DET
dti-2638	184	24	investment	investment	NOUN
dti-2638	184	25	of	of	ADP
dti-2638	184	26	labour	labour	NOUN
dti-2638	184	27	,	,	PUNCT
dti-2638	184	28	time	time	NOUN
dti-2638	184	29	,	,	PUNCT
dti-2638	184	30	and	and	CCONJ
dti-2638	184	31	money	money	NOUN
dti-2638	184	32	.	.	PUNCT
dti-2638	185	1	among	among	ADP
dti-2638	185	2	the	the	DET
dti-2638	185	3	top	top	ADJ
dti-2638	185	4	181	181	NUM
dti-2638	185	5	compounds	compound	NOUN
dti-2638	185	6	predicted	predict	VERB
dti-2638	185	7	through	through	ADP
dti-2638	185	8	virtual	virtual	ADJ
dti-2638	185	9	screening	screening	NOUN
dti-2638	185	10	to	to	PART
dti-2638	185	11	be	be	AUX
dti-2638	185	12	capable	capable	ADJ
dti-2638	185	13	of	of	ADP
dti-2638	185	14	binding	bind	VERB
dti-2638	185	15	to	to	ADP
dti-2638	185	16	nor	nor	CCONJ
dti-2638	185	17	or	or	CCONJ
dti-2638	185	18	lasr	lasr	PROPN
dti-2638	185	19	of	of	ADP
dti-2638	185	20	p.	p.	PROPN
dti-2638	185	21	aeruginosa	aeruginosa	PROPN
dti-2638	185	22	,	,	PUNCT
dti-2638	185	23	we	we	PRON
dti-2638	185	24	could	could	AUX
dti-2638	185	25	detect	detect	VERB
dti-2638	185	26	in	in	ADP
dti-2638	185	27	vivo	vivo	ADJ
dti-2638	185	28	anti	anti	ADJ
dti-2638	185	29	-	-	ADJ
dti-2638	185	30	p.	p.	ADJ
dti-2638	185	31	aeruginosa	aeruginosa	NOUN
dti-2638	185	32	activity	activity	NOUN
dti-2638	185	33	in	in	ADP
dti-2638	185	34	19	19	NUM
dti-2638	185	35	(	(	PUNCT
dti-2638	185	36	i.e.	i.e.	X
dti-2638	185	37	10.4	10.4	NUM
dti-2638	185	38	%	%	NOUN
dti-2638	185	39	of	of	ADP
dti-2638	185	40	all	all	DET
dti-2638	185	41	compounds	compound	NOUN
dti-2638	185	42	tested	test	VERB
dti-2638	185	43	)	)	PUNCT
dti-2638	185	44	of	of	ADP
dti-2638	185	45	them	they	PRON
dti-2638	185	46	in	in	ADP
dti-2638	185	47	the	the	DET
dti-2638	185	48	model	model	NOUN
dti-2638	185	49	host	host	NOUN
dti-2638	185	50	c.	c.	PROPN
dti-2638	185	51	elegans	elegan	NOUN
dti-2638	185	52	.	.	PUNCT
dti-2638	186	1	as	as	ADP
dti-2638	186	2	per	per	ADP
dti-2638	186	3	our	our	PRON
dti-2638	186	4	search	search	NOUN
dti-2638	186	5	on	on	ADP
dti-2638	186	6	pubchem	pubchem	NOUN
dti-2638	186	7	on	on	ADP
dti-2638	186	8	1	1	NUM
dti-2638	186	9	june	june	PROPN
dti-2638	186	10	2023	2023	NUM
dti-2638	186	11	,	,	PUNCT
dti-2638	186	12	these	these	DET
dti-2638	186	13	19	19	NUM
dti-2638	186	14	compounds	compound	NOUN
dti-2638	186	15	have	have	AUX
dti-2638	186	16	yet	yet	ADV
dti-2638	186	17	not	not	PART
dti-2638	186	18	been	be	AUX
dti-2638	186	19	reported	report	VERB
dti-2638	186	20	to	to	PART
dti-2638	186	21	possess	possess	VERB
dti-2638	186	22	any	any	DET
dti-2638	186	23	kind	kind	NOUN
dti-2638	186	24	of	of	ADP
dti-2638	186	25	biological	biological	ADJ
dti-2638	186	26	activity	activity	NOUN
dti-2638	186	27	,	,	PUNCT
dti-2638	186	28	and	and	CCONJ
dti-2638	186	29	hence	hence	ADV
dti-2638	186	30	we	we	PRON
dti-2638	186	31	believe	believe	VERB
dti-2638	186	32	this	this	PRON
dti-2638	186	33	to	to	PART
dti-2638	186	34	be	be	AUX
dti-2638	186	35	the	the	DET
dti-2638	186	36	first	first	ADJ
dti-2638	186	37	report	report	NOUN
dti-2638	186	38	of	of	ADP
dti-2638	186	39	anti	anti	ADJ
dti-2638	186	40	pathogenic	pathogenic	ADJ
dti-2638	186	41	activity	activity	NOUN
dti-2638	186	42	in	in	ADP
dti-2638	186	43	these	these	DET
dti-2638	186	44	compounds	compound	NOUN
dti-2638	186	45	.	.	PUNCT
dti-2638	187	1	further	further	ADJ
dti-2638	187	2	investigation	investigation	NOUN
dti-2638	187	3	on	on	ADP
dti-2638	187	4	these	these	DET
dti-2638	187	5	active	active	ADJ
dti-2638	187	6	compounds	compound	NOUN
dti-2638	187	7	with	with	ADP
dti-2638	187	8	respect	respect	NOUN
dti-2638	187	9	to	to	ADP
dti-2638	187	10	their	their	PRON
dti-2638	187	11	mode	mode	NOUN
dti-2638	187	12	of	of	ADP
dti-2638	187	13	action	action	NOUN
dti-2638	187	14	is	be	AUX
dti-2638	187	15	warranted	warrant	VERB
dti-2638	187	16	,	,	PUNCT
dti-2638	187	17	which	which	PRON
dti-2638	187	18	besides	besides	SCONJ
dti-2638	187	19	confirming	confirm	VERB
dti-2638	187	20	their	their	PRON
dti-2638	187	21	antibacterial	antibacterial	ADJ
dti-2638	187	22	activity	activity	NOUN
dti-2638	187	23	will	will	AUX
dti-2638	187	24	also	also	ADV
dti-2638	187	25	provide	provide	VERB
dti-2638	187	26	additional	additional	ADJ
dti-2638	187	27	validation	validation	NOUN
dti-2638	187	28	to	to	ADP
dti-2638	187	29	the	the	DET
dti-2638	187	30	targetability	targetability	NOUN
dti-2638	187	31	of	of	ADP
dti-2638	187	32	nor	nor	CCONJ
dti-2638	187	33	and	and	CCONJ
dti-2638	187	34	lasr	lasr	PROPN
dti-2638	187	35	.	.	PUNCT
dti-2638	188	1	limitations	limitation	VERB
dti-2638	188	2	the	the	DET
dti-2638	188	3	anti	anti	ADJ
dti-2638	188	4	-	-	ADJ
dti-2638	188	5	virulence	virulence	ADJ
dti-2638	188	6	assay	assay	NOUN
dti-2638	188	7	performed	perform	VERB
dti-2638	188	8	in	in	ADP
dti-2638	188	9	this	this	DET
dti-2638	188	10	study	study	NOUN
dti-2638	188	11	is	be	AUX
dti-2638	188	12	not	not	PART
dti-2638	188	13	specific	specific	ADJ
dti-2638	188	14	to	to	ADP
dti-2638	188	15	lasr	lasr	PROPN
dti-2638	188	16	or	or	CCONJ
dti-2638	188	17	nor	nor	CCONJ
dti-2638	188	18	,	,	PUNCT
dti-2638	188	19	hence	hence	ADV
dti-2638	188	20	precise	precise	ADJ
dti-2638	188	21	mode	mode	NOUN
dti-2638	188	22	of	of	ADP
dti-2638	188	23	action	action	NOUN
dti-2638	188	24	of	of	ADP
dti-2638	188	25	active	active	ADJ
dti-2638	188	26	anti	anti	ADJ
dti-2638	188	27	-	-	ADJ
dti-2638	188	28	pathogenic	pathogenic	ADJ
dti-2638	188	29	compounds	compound	NOUN
dti-2638	188	30	warrants	warrant	NOUN
dti-2638	188	31	further	far	ADV
dti-2638	188	32	confirmatory	confirmatory	ADJ
dti-2638	188	33	assays	assay	NOUN
dti-2638	188	34	.	.	PUNCT
dti-2638	189	1	we	we	PRON
dti-2638	189	2	could	could	AUX
dti-2638	189	3	not	not	PART
dti-2638	189	4	carry	carry	VERB
dti-2638	189	5	out	out	ADP
dti-2638	189	6	in	in	ADP
dti-2638	189	7	vitro	vitro	X
dti-2638	189	8	mic	mic	ADJ
dti-2638	189	9	/	/	SYM
dti-2638	189	10	mbc	mbc	PROPN
dti-2638	189	11	assay	assay	VERB
dti-2638	189	12	for	for	ADP
dti-2638	189	13	active	active	ADJ
dti-2638	189	14	compounds	compound	NOUN
dti-2638	189	15	owing	owe	VERB
dti-2638	189	16	to	to	ADP
dti-2638	189	17	limited	limited	ADJ
dti-2638	189	18	quantity	quantity	NOUN
dti-2638	189	19	at	at	ADP
dti-2638	189	20	our	our	PRON
dti-2638	189	21	disposal	disposal	NOUN
dti-2638	189	22	,	,	PUNCT
dti-2638	189	23	hence	hence	ADV
dti-2638	189	24	it	it	PRON
dti-2638	189	25	was	be	AUX
dti-2638	189	26	not	not	PART
dti-2638	189	27	possible	possible	ADJ
dti-2638	189	28	to	to	PART
dti-2638	189	29	distinguish	distinguish	VERB
dti-2638	189	30	between	between	ADP
dti-2638	189	31	growthinhibitory	growthinhibitory	NOUN
dti-2638	189	32	and	and	CCONJ
dti-2638	189	33	virulence	virulence	NOUN
dti-2638	189	34	-	-	PUNCT
dti-2638	189	35	inhibitory	inhibitory	NOUN
dti-2638	189	36	(	(	PUNCT
dti-2638	189	37	i.e.	i.e.	X
dti-2638	189	38	non	non	ADJ
dti-2638	189	39	-	-	ADJ
dti-2638	189	40	antibiotic	antibiotic	ADJ
dti-2638	189	41	action	action	NOUN
dti-2638	189	42	)	)	PUNCT
dti-2638	189	43	table	table	NOUN
dti-2638	189	44	ii	ii	NOUN
dti-2638	189	45	anti	anti	ADJ
dti-2638	189	46	-	-	ADJ
dti-2638	189	47	pathogenic	pathogenic	ADJ
dti-2638	189	48	activity	activity	NOUN
dti-2638	189	49	of	of	ADP
dti-2638	189	50	potential	potential	ADJ
dti-2638	189	51	lasr	lasr	PROPN
dti-2638	189	52	inhibitors	inhibitor	NOUN
dti-2638	189	53	may	may	AUX
dti-2638	189	54	be	be	AUX
dti-2638	189	55	masked	mask	VERB
dti-2638	189	56	by	by	ADP
dti-2638	189	57	their	their	PRON
dti-2638	189	58	anthelmintic	anthelmintic	ADJ
dti-2638	189	59	activity	activity	NOUN
dti-2638	189	60	lab	lab	NOUN
dti-2638	189	61	code	code	NOUN
dti-2638	189	62	manufacturer	manufacturer	NOUN
dti-2638	189	63	’s	’s	PART
dti-2638	189	64	code	code	NOUN
dti-2638	189	65	conc	conc	NOUN
dti-2638	189	66	(	(	PUNCT
dti-2638	189	67	µg	µg	NOUN
dti-2638	189	68	/	/	SYM
dti-2638	189	69	ml	ml	NOUN
dti-2638	189	70	)	)	PUNCT
dti-2638	189	71	%	%	NOUN
dti-2638	189	72	anti	anti	ADJ
dti-2638	189	73	-	-	ADJ
dti-2638	189	74	pathogenic	pathogenic	ADJ
dti-2638	189	75	activity	activity	NOUN
dti-2638	189	76	based	base	VERB
dti-2638	189	77	on	on	ADP
dti-2638	189	78	fifth	fifth	ADJ
dti-2638	189	79	day	day	NOUN
dti-2638	189	80	end	end	NOUN
dti-2638	189	81	-	-	PUNCT
dti-2638	189	82	point	point	NOUN
dti-2638	189	83	without	without	ADP
dti-2638	189	84	nullifying	nullify	VERB
dti-2638	189	85	compound	compound	NOUN
dti-2638	189	86	’s	’s	PART
dti-2638	189	87	toxicity	toxicity	NOUN
dti-2638	189	88	towards	towards	ADP
dti-2638	189	89	worms	worm	NOUN
dti-2638	189	90	after	after	ADP
dti-2638	189	91	nullifying	nullify	VERB
dti-2638	189	92	compound	compound	NOUN
dti-2638	189	93	’s	’s	PART
dti-2638	189	94	toxicity	toxicity	NOUN
dti-2638	189	95	towards	towards	ADP
dti-2638	189	96	worms	worm	NOUN
dti-2638	189	97	g2	g2	PROPN
dti-2638	189	98	z65195564	z65195564	PROPN
dti-2638	189	99	25	25	NUM
dti-2638	189	100	10	10	NUM
dti-2638	189	101	±	±	NOUN
dti-2638	189	102	0	0	NUM
dti-2638	189	103	*	*	PUNCT
dti-2638	189	104	*	*	PUNCT
dti-2638	189	105	*	*	PUNCT
dti-2638	189	106	67	67	NUM
dti-2638	189	107	±	±	NOUN
dti-2638	189	108	0	0	NUM
dti-2638	189	109	*	*	PUNCT
dti-2638	189	110	*	*	PUNCT
dti-2638	189	111	*	*	PUNCT
dti-2638	190	1	g5	g5	NOUN
dti-2638	190	2	z354444420	z354444420	PROPN
dti-2638	190	3	25	25	NUM
dti-2638	190	4	33	33	NUM
dti-2638	190	5	±	±	NUM
dti-2638	190	6	5	5	NUM
dti-2638	190	7	*	*	PUNCT
dti-2638	190	8	*	*	PUNCT
dti-2638	190	9	*	*	NOUN
dti-2638	190	10	87	87	NUM
dti-2638	190	11	±	±	NUM
dti-2638	190	12	5	5	NUM
dti-2638	190	13	*	*	PUNCT
dti-2638	190	14	*	*	PUNCT
dti-2638	190	15	*	*	PUNCT
dti-2638	191	1	g6	g6	ADJ
dti-2638	191	2	z400859658	z400859658	NUM
dti-2638	191	3	25	25	NUM
dti-2638	191	4	3	3	NUM
dti-2638	191	5	±	±	NUM
dti-2638	191	6	5.7	5.7	NUM
dti-2638	191	7	83	83	NUM
dti-2638	191	8	±	±	NUM
dti-2638	191	9	5.7	5.7	NUM
dti-2638	191	10	*	*	PUNCT
dti-2638	191	11	*	*	PUNCT
dti-2638	191	12	*	*	PROPN
dti-2638	191	13	g10	g10	PROPN
dti-2638	191	14	z1426094174	z1426094174	PROPN
dti-2638	191	15	25	25	NUM
dti-2638	191	16	33	33	NUM
dti-2638	191	17	±	±	NUM
dti-2638	191	18	5	5	NUM
dti-2638	191	19	*	*	PUNCT
dti-2638	191	20	*	*	PUNCT
dti-2638	191	21	*	*	PUNCT
dti-2638	191	22	90	90	NUM
dti-2638	191	23	±	±	NUM
dti-2638	191	24	5	5	NUM
dti-2638	191	25	*	*	PUNCT
dti-2638	191	26	*	*	PUNCT
dti-2638	191	27	*	*	NOUN
dti-2638	191	28	g11	g11	X
dti-2638	191	29	z1625994950	z1625994950	NOUN
dti-2638	191	30	25	25	NUM
dti-2638	191	31	6	6	NUM
dti-2638	191	32	±	±	NUM
dti-2638	191	33	11.5	11.5	NUM
dti-2638	191	34	93	93	NUM
dti-2638	191	35	±	±	NUM
dti-2638	191	36	11.5	11.5	NUM
dti-2638	191	37	*	*	PUNCT
dti-2638	191	38	*	*	PUNCT
dti-2638	191	39	*	*	PUNCT
dti-2638	191	40	g14	g14	ADJ
dti-2638	191	41	z104586200	z104586200	NOUN
dti-2638	191	42	25	25	NUM
dti-2638	191	43	23	23	NUM
dti-2638	191	44	±	±	NUM
dti-2638	191	45	5.7	5.7	NUM
dti-2638	191	46	*	*	SYM
dti-2638	191	47	*	*	PROPN
dti-2638	191	48	50	50	NUM
dti-2638	191	49	±	±	NUM
dti-2638	191	50	5.7	5.7	NUM
dti-2638	191	51	*	*	PUNCT
dti-2638	191	52	*	*	PUNCT
dti-2638	191	53	*	*	PROPN
dti-2638	191	54	g18	g18	PROPN
dti-2638	191	55	z1084397894	z1084397894	PROPN
dti-2638	191	56	25	25	NUM
dti-2638	191	57	16	16	NUM
dti-2638	191	58	±	±	NUM
dti-2638	191	59	5.7	5.7	NUM
dti-2638	191	60	*	*	PUNCT
dti-2638	191	61	*	*	PROPN
dti-2638	191	62	63	63	NUM
dti-2638	191	63	±	±	NUM
dti-2638	191	64	5.7	5.7	NUM
dti-2638	191	65	*	*	PUNCT
dti-2638	191	66	*	*	PUNCT
dti-2638	191	67	*	*	PUNCT
dti-2638	191	68	g19	g19	PROPN
dti-2638	191	69	z1212781307	z1212781307	NUM
dti-2638	191	70	25	25	NUM
dti-2638	191	71	26	26	NUM
dti-2638	191	72	±	±	NUM
dti-2638	191	73	11.5	11.5	NUM
dti-2638	191	74	*	*	SYM
dti-2638	191	75	*	*	PROPN
dti-2638	191	76	53	53	NUM
dti-2638	191	77	±	±	NUM
dti-2638	191	78	11.5	11.5	NUM
dti-2638	191	79	*	*	PUNCT
dti-2638	191	80	*	*	PUNCT
dti-2638	191	81	*	*	PUNCT
dti-2638	191	82	g38	g38	NOUN
dti-2638	191	83	z89293640	z89293640	NUM
dti-2638	191	84	50	50	NUM
dti-2638	191	85	6	6	NUM
dti-2638	191	86	±	±	NUM
dti-2638	191	87	5.7	5.7	NUM
dti-2638	191	88	20	20	NUM
dti-2638	191	89	±	±	NUM
dti-2638	191	90	5.7	5.7	NUM
dti-2638	191	91	*	*	PUNCT
dti-2638	191	92	*	*	PUNCT
dti-2638	192	1	*	*	PUNCT
dti-2638	192	2	*	*	PUNCT
dti-2638	192	3	p<0.01	p<0.01	PROPN
dti-2638	192	4	,	,	PUNCT
dti-2638	192	5	*	*	PUNCT
dti-2638	192	6	*	*	PUNCT
dti-2638	192	7	*	*	PUNCT
dti-2638	192	8	p<0.001	p<0.001	PROPN
dti-2638	192	9	.	.	PUNCT
dti-2638	193	1	gajera	gajera	PROPN
dti-2638	193	2	et	et	PROPN
dti-2638	193	3	al	al	PROPN
dti-2638	193	4	drug	drug	PROPN
dti-2638	193	5	target	target	NOUN
dti-2638	193	6	insights	insight	NOUN
dti-2638	193	7	2023	2023	NUM
dti-2638	193	8	;	;	PUNCT
dti-2638	193	9	17	17	NUM
dti-2638	193	10	:	:	SYM
dti-2638	193	11	107	107	NUM
dti-2638	193	12	©	©	PROPN
dti-2638	193	13	2023	2023	NUM
dti-2638	193	14	the	the	DET
dti-2638	193	15	authors	author	NOUN
dti-2638	193	16	.	.	PUNCT
dti-2638	194	1	published	publish	VERB
dti-2638	194	2	by	by	ADP
dti-2638	194	3	aboutscience	aboutscience	NOUN
dti-2638	194	4	www.aboutscience.eu	www.aboutscience.eu	NOUN
dti-2638	194	5	fig	fig	NOUN
dti-2638	194	6	.	.	PUNCT
dti-2638	195	1	4	4	NUM
dti-2638	195	2	pseudomonas	pseudomona	NOUN
dti-2638	195	3	aeruginosa	aeruginosa	NOUN
dti-2638	195	4	’s	’s	PART
dti-2638	195	5	virulence	virulence	NOUN
dti-2638	195	6	towards	towards	ADP
dti-2638	195	7	the	the	DET
dti-2638	195	8	host	host	NOUN
dti-2638	195	9	worm	worm	NOUN
dti-2638	195	10	gets	get	AUX
dti-2638	195	11	attenuated	attenuate	VERB
dti-2638	195	12	in	in	ADP
dti-2638	195	13	the	the	DET
dti-2638	195	14	presence	presence	NOUN
dti-2638	195	15	of	of	ADP
dti-2638	195	16	certain	certain	ADJ
dti-2638	195	17	predicted	predict	VERB
dti-2638	195	18	nitric	nitric	ADJ
dti-2638	195	19	oxide	oxide	NOUN
dti-2638	195	20	reductase	reductase	NOUN
dti-2638	195	21	(	(	PUNCT
dti-2638	195	22	nor	nor	CCONJ
dti-2638	195	23	)	)	PUNCT
dti-2638	195	24	inhibitors	inhibitor	NOUN
dti-2638	195	25	.	.	PUNCT
dti-2638	196	1	a	a	DET
dti-2638	196	2	)	)	PUNCT
dti-2638	196	3	p.	p.	NOUN
dti-2638	196	4	aeruginosa	aeruginosa	NOUN
dti-2638	196	5	could	could	AUX
dti-2638	196	6	kill	kill	VERB
dti-2638	196	7	70%±0	70%±0	NUM
dti-2638	196	8	%	%	NOUN
dti-2638	196	9	*	*	PUNCT
dti-2638	196	10	*	*	PUNCT
dti-2638	196	11	*	*	PUNCT
dti-2638	196	12	and	and	CCONJ
dti-2638	196	13	55%±7	55%±7	NUM
dti-2638	196	14	%	%	NOUN
dti-2638	196	15	*	*	PUNCT
dti-2638	196	16	*	*	PUNCT
dti-2638	196	17	lesser	less	ADJ
dti-2638	196	18	worms	worm	NOUN
dti-2638	196	19	in	in	ADP
dti-2638	196	20	the	the	DET
dti-2638	196	21	presence	presence	NOUN
dti-2638	196	22	of	of	ADP
dti-2638	196	23	n4	n4	PROPN
dti-2638	196	24	(	(	PUNCT
dti-2638	196	25	z954454636	z954454636	PROPN
dti-2638	196	26	)	)	PUNCT
dti-2638	196	27	and	and	CCONJ
dti-2638	196	28	n14	n14	PROPN
dti-2638	196	29	(	(	PUNCT
dti-2638	196	30	z1765101069	z1765101069	PROPN
dti-2638	196	31	)	)	PUNCT
dti-2638	196	32	,	,	PUNCT
dti-2638	196	33	respectively	respectively	ADV
dti-2638	196	34	.	.	PUNCT
dti-2638	197	1	b	b	X
dti-2638	197	2	)	)	PUNCT
dti-2638	197	3	p.	p.	NOUN
dti-2638	197	4	aeruginosa	aeruginosa	NOUN
dti-2638	197	5	could	could	AUX
dti-2638	197	6	kill	kill	VERB
dti-2638	197	7	50%±0	50%±0	NUM
dti-2638	197	8	%	%	NOUN
dti-2638	197	9	*	*	PUNCT
dti-2638	197	10	*	*	PUNCT
dti-2638	197	11	*	*	PROPN
dti-2638	197	12	and	and	CCONJ
dti-2638	197	13	40%±14	40%±14	NUM
dti-2638	197	14	%	%	NOUN
dti-2638	197	15	*	*	PUNCT
dti-2638	197	16	*	*	PUNCT
dti-2638	197	17	lesser	less	ADJ
dti-2638	197	18	worms	worm	NOUN
dti-2638	197	19	in	in	ADP
dti-2638	197	20	the	the	DET
dti-2638	197	21	presence	presence	NOUN
dti-2638	197	22	of	of	ADP
dti-2638	197	23	n18	n18	PROPN
dti-2638	197	24	(	(	PUNCT
dti-2638	197	25	z110018576	z110018576	PROPN
dti-2638	197	26	)	)	PUNCT
dti-2638	197	27	and	and	CCONJ
dti-2638	197	28	n27	n27	PROPN
dti-2638	197	29	(	(	PUNCT
dti-2638	197	30	z1611882500	z1611882500	NOUN
dti-2638	197	31	)	)	PUNCT
dti-2638	197	32	,	,	PUNCT
dti-2638	197	33	respectively	respectively	ADV
dti-2638	197	34	.	.	PUNCT
dti-2638	198	1	c	c	X
dti-2638	198	2	)	)	PUNCT
dti-2638	198	3	p.	p.	NOUN
dti-2638	198	4	aeruginosa	aeruginosa	NOUN
dti-2638	198	5	could	could	AUX
dti-2638	198	6	kill	kill	VERB
dti-2638	198	7	65%±7	65%±7	NUM
dti-2638	198	8	%	%	NOUN
dti-2638	198	9	*	*	PUNCT
dti-2638	198	10	and	and	CCONJ
dti-2638	198	11	85%±7	85%±7	NUM
dti-2638	198	12	%	%	NOUN
dti-2638	198	13	*	*	PUNCT
dti-2638	198	14	*	*	PUNCT
dti-2638	198	15	lesser	less	ADJ
dti-2638	198	16	worms	worm	NOUN
dti-2638	198	17	in	in	ADP
dti-2638	198	18	the	the	DET
dti-2638	198	19	presence	presence	NOUN
dti-2638	198	20	of	of	ADP
dti-2638	198	21	n36	n36	NOUN
dti-2638	198	22	(	(	PUNCT
dti-2638	198	23	z397755956	z397755956	PROPN
dti-2638	198	24	)	)	PUNCT
dti-2638	198	25	and	and	CCONJ
dti-2638	198	26	n37	n37	NOUN
dti-2638	198	27	(	(	PUNCT
dti-2638	198	28	z1190350270	z1190350270	NUM
dti-2638	198	29	)	)	PUNCT
dti-2638	198	30	,	,	PUNCT
dti-2638	198	31	respectively	respectively	ADV
dti-2638	198	32	.	.	PUNCT
dti-2638	199	1	d	d	X
dti-2638	199	2	)	)	PUNCT
dti-2638	199	3	p.	p.	NOUN
dti-2638	199	4	aeruginosa	aeruginosa	NOUN
dti-2638	199	5	could	could	AUX
dti-2638	199	6	kill	kill	VERB
dti-2638	199	7	50%±14	50%±14	NUM
dti-2638	199	8	%	%	NOUN
dti-2638	199	9	*	*	NOUN
dti-2638	199	10	*	*	NOUN
dti-2638	199	11	,	,	PUNCT
dti-2638	199	12	55%±0.7	55%±0.7	NUM
dti-2638	199	13	%	%	NOUN
dti-2638	199	14	*	*	PUNCT
dti-2638	199	15	*	*	PUNCT
dti-2638	199	16	,	,	PUNCT
dti-2638	199	17	and	and	CCONJ
dti-2638	199	18	100%±0	100%±0	NUM
dti-2638	199	19	%	%	NOUN
dti-2638	199	20	*	*	PUNCT
dti-2638	199	21	*	*	PUNCT
dti-2638	199	22	*	*	PUNCT
dti-2638	199	23	lesser	less	ADJ
dti-2638	199	24	worms	worm	NOUN
dti-2638	199	25	in	in	ADP
dti-2638	199	26	the	the	DET
dti-2638	199	27	presence	presence	NOUN
dti-2638	199	28	of	of	ADP
dti-2638	199	29	n61	n61	PROPN
dti-2638	199	30	(	(	PUNCT
dti-2638	199	31	z2740017161	z2740017161	NUM
dti-2638	199	32	)	)	PUNCT
dti-2638	199	33	,	,	PUNCT
dti-2638	199	34	n65	n65	NOUN
dti-2638	199	35	(	(	PUNCT
dti-2638	199	36	z1874308288	z1874308288	NUM
dti-2638	199	37	)	)	PUNCT
dti-2638	199	38	,	,	PUNCT
dti-2638	199	39	and	and	CCONJ
dti-2638	199	40	ofloxacin	ofloxacin	NOUN
dti-2638	199	41	(	(	PUNCT
dti-2638	199	42	0.5	0.5	NUM
dti-2638	199	43	µg	µg	NOUN
dti-2638	199	44	/	/	SYM
dti-2638	199	45	ml	ml	NOUN
dti-2638	199	46	)	)	PUNCT
dti-2638	199	47	,	,	PUNCT
dti-2638	199	48	respectively	respectively	ADV
dti-2638	199	49	.	.	PUNCT
dti-2638	200	1	later	later	ADV
dti-2638	200	2	it	it	PRON
dti-2638	200	3	was	be	AUX
dti-2638	200	4	employed	employ	VERB
dti-2638	200	5	as	as	ADP
dti-2638	200	6	a	a	DET
dti-2638	200	7	positive	positive	ADJ
dti-2638	200	8	control	control	NOUN
dti-2638	200	9	at	at	ADP
dti-2638	200	10	its	its	PRON
dti-2638	200	11	subminimum	subminimum	ADJ
dti-2638	200	12	inhibitory	inhibitory	ADJ
dti-2638	200	13	concentration	concentration	NOUN
dti-2638	200	14	(	(	PUNCT
dti-2638	200	15	mic	mic	ADJ
dti-2638	200	16	)	)	PUNCT
dti-2638	200	17	level	level	NOUN
dti-2638	200	18	,	,	PUNCT
dti-2638	200	19	and	and	CCONJ
dti-2638	200	20	it	it	PRON
dti-2638	200	21	did	do	AUX
dti-2638	200	22	allow	allow	VERB
dti-2638	200	23	progeny	progeny	ADJ
dti-2638	200	24	formation	formation	NOUN
dti-2638	200	25	in	in	ADP
dti-2638	200	26	worm	worm	NOUN
dti-2638	200	27	population	population	NOUN
dti-2638	200	28	from	from	ADP
dti-2638	200	29	the	the	DET
dti-2638	200	30	third	third	ADJ
dti-2638	200	31	day	day	NOUN
dti-2638	200	32	onwards	onwards	ADV
dti-2638	200	33	.	.	PUNCT
dti-2638	201	1	dimethyl	dimethyl	NOUN
dti-2638	201	2	sulfoxide	sulfoxide	NOUN
dti-2638	201	3	(	(	PUNCT
dti-2638	201	4	dmso	dmso	NOUN
dti-2638	201	5	;	;	PUNCT
dti-2638	201	6	0.5	0.5	NUM
dti-2638	201	7	%	%	NOUN
dti-2638	201	8	v	v	ADP
dti-2638	201	9	/	/	SYM
dti-2638	201	10	v	v	NOUN
dti-2638	201	11	)	)	PUNCT
dti-2638	201	12	present	present	ADJ
dti-2638	201	13	in	in	ADP
dti-2638	201	14	the	the	DET
dti-2638	201	15	‘	'	PUNCT
dti-2638	201	16	vehicle	vehicle	NOUN
dti-2638	201	17	control	control	NOUN
dti-2638	201	18	’	'	PUNCT
dti-2638	201	19	neither	neither	CCONJ
dti-2638	201	20	affected	affect	VERB
dti-2638	201	21	virulence	virulence	NOUN
dti-2638	201	22	of	of	ADP
dti-2638	201	23	the	the	DET
dti-2638	201	24	bacterium	bacterium	NOUN
dti-2638	201	25	towards	towards	ADP
dti-2638	201	26	caenorhabditis	caenorhabditis	ADJ
dti-2638	201	27	elegans	elegan	NOUN
dti-2638	201	28	,	,	PUNCT
dti-2638	201	29	nor	nor	CCONJ
dti-2638	201	30	did	do	AUX
dti-2638	201	31	it	it	PRON
dti-2638	201	32	show	show	VERB
dti-2638	201	33	any	any	DET
dti-2638	201	34	effect	effect	NOUN
dti-2638	201	35	on	on	ADP
dti-2638	201	36	worm	worm	NOUN
dti-2638	201	37	survival	survival	NOUN
dti-2638	201	38	.	.	PUNCT
dti-2638	202	1	*	*	PUNCT
dti-2638	202	2	*	*	PUNCT
dti-2638	202	3	p<0.01	p<0.01	PROPN
dti-2638	202	4	,	,	PUNCT
dti-2638	202	5	*	*	PUNCT
dti-2638	202	6	*	*	PUNCT
dti-2638	202	7	*	*	PUNCT
dti-2638	202	8	p<0.001	p<0.001	ADJ
dti-2638	202	9	.	.	PUNCT
dti-2638	203	1	the	the	DET
dti-2638	203	2	percent	percent	NOUN
dti-2638	203	3	values	value	NOUN
dti-2638	203	4	reported	report	VERB
dti-2638	203	5	pertain	pertain	NOUN
dti-2638	203	6	to	to	ADP
dti-2638	203	7	the	the	DET
dti-2638	203	8	worm	worm	NOUN
dti-2638	203	9	survival	survival	NOUN
dti-2638	203	10	2	2	NUM
dti-2638	203	11	days	day	NOUN
dti-2638	203	12	post	post	ADJ
dti-2638	203	13	-	-	NOUN
dti-2638	203	14	infection	infection	NOUN
dti-2638	203	15	.	.	PUNCT
dti-2638	204	1	table	table	NOUN
dti-2638	204	2	iii	iii	NOUN
dti-2638	204	3	list	list	NOUN
dti-2638	204	4	of	of	ADP
dti-2638	204	5	predicted	predict	VERB
dti-2638	204	6	nor	nor	CCONJ
dti-2638	204	7	inhibitors	inhibitor	NOUN
dti-2638	204	8	found	find	VERB
dti-2638	204	9	to	to	PART
dti-2638	204	10	possess	possess	VERB
dti-2638	204	11	in	in	ADP
dti-2638	204	12	vivo	vivo	ADJ
dti-2638	204	13	anti	anti	ADJ
dti-2638	204	14	-	-	ADJ
dti-2638	204	15	pseudomonas	pseudomonas	ADJ
dti-2638	204	16	aeruginosa	aeruginosa	NOUN
dti-2638	204	17	activity	activity	NOUN
dti-2638	204	18	lab	lab	NOUN
dti-2638	204	19	code	code	NOUN
dti-2638	204	20	manufacturer	manufacturer	NOUN
dti-2638	204	21	’s	’s	PART
dti-2638	204	22	code	code	NOUN
dti-2638	204	23	conc	conc	NOUN
dti-2638	204	24	.	.	PUNCT
dti-2638	205	1	(	(	PUNCT
dti-2638	205	2	µg	µg	NOUN
dti-2638	205	3	/	/	SYM
dti-2638	205	4	ml	ml	NOUN
dti-2638	205	5	)	)	PUNCT
dti-2638	205	6	%	%	NOUN
dti-2638	205	7	reduction	reduction	NOUN
dti-2638	205	8	in	in	ADP
dti-2638	205	9	bacterial	bacterial	ADJ
dti-2638	205	10	virulence	virulence	NOUN
dti-2638	205	11	1st	1st	ADJ
dti-2638	205	12	day	day	NOUN
dti-2638	205	13	end	end	NOUN
dti-2638	205	14	-	-	PUNCT
dti-2638	205	15	point	point	NOUN
dti-2638	205	16	2nd	2nd	ADJ
dti-2638	205	17	day	day	NOUN
dti-2638	205	18	end	end	NOUN
dti-2638	205	19	-	-	PUNCT
dti-2638	205	20	point	point	NOUN
dti-2638	205	21	n4	n4	PROPN
dti-2638	205	22	z954454636	z954454636	PROPN
dti-2638	205	23	25	25	NUM
dti-2638	205	24	95	95	NUM
dti-2638	205	25	±	±	NUM
dti-2638	205	26	7	7	NUM
dti-2638	205	27	*	*	PUNCT
dti-2638	205	28	*	*	PUNCT
dti-2638	205	29	*	*	PUNCT
dti-2638	205	30	70	70	NUM
dti-2638	205	31	±	±	NOUN
dti-2638	205	32	0	0	NUM
dti-2638	205	33	*	*	PUNCT
dti-2638	205	34	*	*	PUNCT
dti-2638	205	35	*	*	PUNCT
dti-2638	205	36	n14	n14	PROPN
dti-2638	205	37	z1765101069	z1765101069	PROPN
dti-2638	205	38	25	25	NUM
dti-2638	205	39	85	85	NUM
dti-2638	205	40	±	±	NUM
dti-2638	205	41	7	7	NUM
dti-2638	205	42	*	*	SYM
dti-2638	205	43	*	*	PROPN
dti-2638	205	44	55	55	NUM
dti-2638	205	45	±	±	NUM
dti-2638	205	46	7	7	NUM
dti-2638	205	47	*	*	SYM
dti-2638	205	48	*	*	PROPN
dti-2638	205	49	n18	n18	NUM
dti-2638	205	50	z110018576	z110018576	PROPN
dti-2638	205	51	25	25	NUM
dti-2638	205	52	75	75	NUM
dti-2638	205	53	±	±	NUM
dti-2638	205	54	7	7	NUM
dti-2638	205	55	*	*	SYM
dti-2638	205	56	*	*	PROPN
dti-2638	205	57	50	50	NUM
dti-2638	205	58	±	±	NOUN
dti-2638	205	59	0	0	NUM
dti-2638	205	60	*	*	PUNCT
dti-2638	205	61	*	*	PUNCT
dti-2638	205	62	*	*	PUNCT
dti-2638	205	63	n27	n27	PROPN
dti-2638	205	64	z1611882500	z1611882500	PROPN
dti-2638	205	65	25	25	NUM
dti-2638	205	66	80	80	NUM
dti-2638	205	67	±	±	NOUN
dti-2638	205	68	0	0	NUM
dti-2638	205	69	*	*	PUNCT
dti-2638	205	70	*	*	PUNCT
dti-2638	205	71	*	*	PUNCT
dti-2638	205	72	40	40	NUM
dti-2638	205	73	±	±	NUM
dti-2638	205	74	14	14	NUM
dti-2638	205	75	*	*	SYM
dti-2638	205	76	n36	n36	NOUN
dti-2638	205	77	z397755956	z397755956	NOUN
dti-2638	205	78	25	25	NUM
dti-2638	205	79	100	100	NUM
dti-2638	205	80	±	±	NUM
dti-2638	205	81	0	0	NUM
dti-2638	205	82	*	*	PUNCT
dti-2638	205	83	*	*	PUNCT
dti-2638	205	84	*	*	PUNCT
dti-2638	205	85	65	65	NUM
dti-2638	205	86	±	±	NUM
dti-2638	205	87	7	7	NUM
dti-2638	205	88	*	*	NOUN
dti-2638	205	89	n37	n37	NOUN
dti-2638	205	90	z1190350270	z1190350270	NUM
dti-2638	205	91	25	25	NUM
dti-2638	205	92	95	95	NUM
dti-2638	205	93	±	±	NUM
dti-2638	205	94	7	7	NUM
dti-2638	205	95	*	*	SYM
dti-2638	205	96	*	*	NUM
dti-2638	205	97	85	85	NUM
dti-2638	205	98	±	±	NUM
dti-2638	205	99	7	7	NUM
dti-2638	205	100	*	*	PUNCT
dti-2638	205	101	*	*	PUNCT
dti-2638	205	102	n61	n61	PROPN
dti-2638	205	103	z2740017161	z2740017161	VERB
dti-2638	205	104	50	50	NUM
dti-2638	205	105	85	85	NUM
dti-2638	205	106	±	±	NUM
dti-2638	205	107	7	7	NUM
dti-2638	205	108	*	*	SYM
dti-2638	205	109	*	*	PROPN
dti-2638	205	110	50	50	NUM
dti-2638	205	111	±	±	NUM
dti-2638	205	112	14	14	NUM
dti-2638	205	113	*	*	PUNCT
dti-2638	205	114	*	*	NOUN
dti-2638	205	115	n65	n65	PROPN
dti-2638	205	116	z1874308288	z1874308288	NUM
dti-2638	205	117	25	25	NUM
dti-2638	205	118	70	70	NUM
dti-2638	205	119	±	±	NOUN
dti-2638	205	120	0	0	NUM
dti-2638	205	121	*	*	PUNCT
dti-2638	205	122	*	*	PUNCT
dti-2638	205	123	*	*	PUNCT
dti-2638	205	124	55	55	NUM
dti-2638	205	125	±	±	NUM
dti-2638	205	126	0.7	0.7	NUM
dti-2638	205	127	*	*	PUNCT
dti-2638	205	128	*	*	PUNCT
dti-2638	205	129	*	*	PUNCT
dti-2638	205	130	*	*	PUNCT
dti-2638	205	131	p<0.01	p<0.01	PROPN
dti-2638	205	132	,	,	PUNCT
dti-2638	205	133	*	*	PUNCT
dti-2638	205	134	*	*	PUNCT
dti-2638	205	135	*	*	PUNCT
dti-2638	205	136	p<0.001	p<0.001	ADJ
dti-2638	205	137	.	.	PUNCT
dti-2638	206	1	nor	nor	CCONJ
dti-2638	206	2	=	=	SYM
dti-2638	206	3	nitric	nitric	ADJ
dti-2638	206	4	oxide	oxide	NOUN
dti-2638	206	5	reductase	reductase	NOUN
dti-2638	206	6	.	.	PUNCT
dti-2638	207	1	table	table	NOUN
dti-2638	207	2	iv	iv	NUM
dti-2638	207	3	anti	anti	ADJ
dti-2638	207	4	-	-	ADJ
dti-2638	207	5	pathogenic	pathogenic	ADJ
dti-2638	207	6	activity	activity	NOUN
dti-2638	207	7	of	of	ADP
dti-2638	207	8	potential	potential	NOUN
dti-2638	207	9	nor	nor	CCONJ
dti-2638	207	10	inhibitors	inhibitor	NOUN
dti-2638	207	11	may	may	AUX
dti-2638	207	12	be	be	AUX
dti-2638	207	13	masked	mask	VERB
dti-2638	207	14	by	by	ADP
dti-2638	207	15	their	their	PRON
dti-2638	207	16	anthelmintic	anthelmintic	ADJ
dti-2638	207	17	activity	activity	NOUN
dti-2638	207	18	lab	lab	NOUN
dti-2638	207	19	code	code	NOUN
dti-2638	207	20	manufacturer	manufacturer	NOUN
dti-2638	207	21	’s	’s	PART
dti-2638	207	22	code	code	NOUN
dti-2638	207	23	conc	conc	NOUN
dti-2638	207	24	(	(	PUNCT
dti-2638	207	25	µg	µg	NOUN
dti-2638	207	26	/	/	SYM
dti-2638	207	27	ml	ml	NOUN
dti-2638	207	28	)	)	PUNCT
dti-2638	207	29	%	%	NOUN
dti-2638	207	30	anti	anti	ADJ
dti-2638	207	31	-	-	ADJ
dti-2638	207	32	pathogenic	pathogenic	ADJ
dti-2638	207	33	activity	activity	NOUN
dti-2638	207	34	based	base	VERB
dti-2638	207	35	on	on	ADP
dti-2638	207	36	fifth	fifth	ADJ
dti-2638	207	37	day	day	NOUN
dti-2638	207	38	end	end	NOUN
dti-2638	207	39	-	-	PUNCT
dti-2638	207	40	point	point	NOUN
dti-2638	207	41	without	without	ADP
dti-2638	207	42	nullifying	nullify	VERB
dti-2638	207	43	compound	compound	NOUN
dti-2638	207	44	’s	’s	PART
dti-2638	207	45	toxicity	toxicity	NOUN
dti-2638	207	46	towards	towards	ADP
dti-2638	207	47	worms	worm	NOUN
dti-2638	207	48	after	after	ADP
dti-2638	207	49	nullifying	nullify	VERB
dti-2638	207	50	compound	compound	NOUN
dti-2638	207	51	’s	’s	PART
dti-2638	207	52	toxicity	toxicity	NOUN
dti-2638	207	53	towards	towards	ADP
dti-2638	207	54	worms	worm	NOUN
dti-2638	207	55	(	(	PUNCT
dti-2638	207	56	a	a	NOUN
dti-2638	207	57	)	)	PUNCT
dti-2638	207	58	(	(	PUNCT
dti-2638	207	59	b	b	X
dti-2638	207	60	)	)	PUNCT
dti-2638	207	61	n4	n4	PROPN
dti-2638	207	62	z954454636	z954454636	PROPN
dti-2638	207	63	25	25	NUM
dti-2638	207	64	25	25	NUM
dti-2638	207	65	±	±	NUM
dti-2638	207	66	7	7	NUM
dti-2638	207	67	*	*	SYM
dti-2638	207	68	*	*	PROPN
dti-2638	207	69	60	60	NUM
dti-2638	207	70	±	±	NUM
dti-2638	207	71	7	7	NUM
dti-2638	207	72	*	*	NOUN
dti-2638	207	73	*	*	PUNCT
dti-2638	207	74	n36	n36	NOUN
dti-2638	207	75	z397755956	z397755956	NOUN
dti-2638	207	76	25	25	NUM
dti-2638	207	77	40	40	NUM
dti-2638	207	78	±	±	NOUN
dti-2638	207	79	0	0	NUM
dti-2638	207	80	*	*	PUNCT
dti-2638	207	81	*	*	PROPN
dti-2638	207	82	65	65	NUM
dti-2638	207	83	±	±	NOUN
dti-2638	207	84	0	0	NUM
dti-2638	207	85	*	*	PUNCT
dti-2638	207	86	*	*	PUNCT
dti-2638	207	87	*	*	NOUN
dti-2638	207	88	n37	n37	NOUN
dti-2638	207	89	z1190350270	z1190350270	NUM
dti-2638	207	90	25	25	NUM
dti-2638	207	91	20	20	NUM
dti-2638	207	92	±	±	NOUN
dti-2638	207	93	0	0	NUM
dti-2638	207	94	*	*	PUNCT
dti-2638	207	95	*	*	PUNCT
dti-2638	207	96	*	*	PUNCT
dti-2638	207	97	45	45	NUM
dti-2638	207	98	±	±	NOUN
dti-2638	207	99	0	0	NUM
dti-2638	207	100	*	*	PUNCT
dti-2638	207	101	*	*	PUNCT
dti-2638	207	102	*	*	PUNCT
dti-2638	207	103	n61	n61	PROPN
dti-2638	207	104	z2740017161	z2740017161	VERB
dti-2638	207	105	50	50	NUM
dti-2638	207	106	20	20	NUM
dti-2638	207	107	±	±	NUM
dti-2638	207	108	14	14	NUM
dti-2638	207	109	80	80	NUM
dti-2638	207	110	±	±	NUM
dti-2638	207	111	14	14	NUM
dti-2638	207	112	*	*	PUNCT
dti-2638	207	113	*	*	NOUN
dti-2638	207	114	n65	n65	PROPN
dti-2638	207	115	z1874308288	z1874308288	NUM
dti-2638	207	116	25	25	NUM
dti-2638	207	117	15	15	NUM
dti-2638	207	118	±	±	NUM
dti-2638	207	119	21	21	NUM
dti-2638	207	120	40	40	NUM
dti-2638	207	121	±	±	NUM
dti-2638	207	122	21	21	NUM
dti-2638	207	123	*	*	PUNCT
dti-2638	207	124	*	*	PUNCT
dti-2638	207	125	*	*	PUNCT
dti-2638	207	126	*	*	PUNCT
dti-2638	207	127	p<0.01	p<0.01	PROPN
dti-2638	207	128	,	,	PUNCT
dti-2638	207	129	*	*	PUNCT
dti-2638	207	130	*	*	PUNCT
dti-2638	207	131	*	*	PUNCT
dti-2638	207	132	p<0.001	p<0.001	ADJ
dti-2638	207	133	.	.	PUNCT
dti-2638	208	1	nor	nor	CCONJ
dti-2638	208	2	=	=	SYM
dti-2638	208	3	nitric	nitric	ADJ
dti-2638	208	4	oxide	oxide	NOUN
dti-2638	208	5	reductase	reductase	NOUN
dti-2638	208	6	.	.	PUNCT
dti-2638	209	1	small	small	ADJ
dti-2638	209	2	-	-	PUNCT
dti-2638	209	3	molecule	molecule	NOUN
dti-2638	209	4	inhibitors	inhibitor	NOUN
dti-2638	209	5	of	of	ADP
dti-2638	209	6	pseudomonas	pseudomona	NOUN
dti-2638	209	7	aeruginosa	aeruginosa	NOUN
dti-2638	209	8	lasr	lasr	PROPN
dti-2638	209	9	or	or	CCONJ
dti-2638	209	10	nor108	nor108	PROPN
dti-2638	209	11	©	©	PROPN
dti-2638	209	12	2023	2023	NUM
dti-2638	209	13	the	the	DET
dti-2638	209	14	authors	author	NOUN
dti-2638	209	15	.	.	PUNCT
dti-2638	210	1	drug	drug	NOUN
dti-2638	210	2	target	target	NOUN
dti-2638	210	3	insights	insight	NOUN
dti-2638	210	4	issn	issn	VERB
dti-2638	210	5	1177	1177	NUM
dti-2638	210	6	-	-	SYM
dti-2638	210	7	3928	3928	NUM
dti-2638	210	8	www.aboutscience.eu/dti	www.aboutscience.eu/dti	NOUN
dti-2638	210	9	activity	activity	NOUN
dti-2638	210	10	.	.	PUNCT
dti-2638	211	1	further	far	ADV
dti-2638	211	2	,	,	PUNCT
dti-2638	211	3	anti	anti	ADJ
dti-2638	211	4	-	-	ADJ
dti-2638	211	5	pathogenic	pathogenic	ADJ
dti-2638	211	6	activity	activity	NOUN
dti-2638	211	7	of	of	ADP
dti-2638	211	8	some	some	PRON
dti-2638	211	9	of	of	ADP
dti-2638	211	10	the	the	DET
dti-2638	211	11	compounds	compound	NOUN
dti-2638	211	12	might	might	AUX
dti-2638	211	13	be	be	AUX
dti-2638	211	14	masked	mask	VERB
dti-2638	211	15	by	by	ADP
dti-2638	211	16	their	their	PRON
dti-2638	211	17	anthelmintic	anthelmintic	ADJ
dti-2638	211	18	activity	activity	NOUN
dti-2638	211	19	(	(	PUNCT
dti-2638	211	20	tabs	tab	NOUN
dti-2638	211	21	.	.	PUNCT
dti-2638	212	1	ii	ii	PROPN
dti-2638	212	2	-	-	PUNCT
dti-2638	212	3	iv	iv	NUM
dti-2638	212	4	)	)	PUNCT
dti-2638	212	5	.	.	PUNCT
dti-2638	213	1	acknowledgements	acknowledgement	NOUN
dti-2638	213	2	authors	author	NOUN
dti-2638	213	3	thank	thank	VERB
dti-2638	213	4	nirma	nirma	VERB
dti-2638	213	5	education	education	NOUN
dti-2638	213	6	and	and	CCONJ
dti-2638	213	7	research	research	NOUN
dti-2638	213	8	foundation	foundation	NOUN
dti-2638	213	9	(	(	PUNCT
dti-2638	213	10	nerf	nerf	PROPN
dti-2638	213	11	)	)	PUNCT
dti-2638	213	12	,	,	PUNCT
dti-2638	213	13	ahmedabad	ahmedabad	PROPN
dti-2638	213	14	,	,	PUNCT
dti-2638	213	15	for	for	ADP
dti-2638	213	16	infrastructural	infrastructural	ADJ
dti-2638	213	17	support	support	NOUN
dti-2638	213	18	.	.	PUNCT
dti-2638	214	1	gg	gg	NOUN
dti-2638	214	2	acknowledges	acknowledge	VERB
dti-2638	214	3	scholarship	scholarship	NOUN
dti-2638	214	4	from	from	ADP
dti-2638	214	5	the	the	DET
dti-2638	214	6	government	government	NOUN
dti-2638	214	7	of	of	ADP
dti-2638	214	8	gujarat	gujarat	PROPN
dti-2638	214	9	through	through	ADP
dti-2638	214	10	their	their	PRON
dti-2638	214	11	shodh	shodh	NOUN
dti-2638	214	12	scheme	scheme	NOUN
dti-2638	214	13	.	.	PUNCT
dti-2638	215	1	disclosures	disclosure	VERB
dti-2638	215	2	conflict	conflict	NOUN
dti-2638	215	3	of	of	ADP
dti-2638	215	4	interest	interest	NOUN
dti-2638	215	5	:	:	PUNCT
dti-2638	215	6	the	the	DET
dti-2638	215	7	authors	author	NOUN
dti-2638	215	8	declare	declare	VERB
dti-2638	215	9	no	no	DET
dti-2638	215	10	conflict	conflict	NOUN
dti-2638	215	11	of	of	ADP
dti-2638	215	12	interest	interest	NOUN
dti-2638	215	13	.	.	PUNCT
dti-2638	216	1	financial	financial	ADJ
dti-2638	216	2	support	support	NOUN
dti-2638	216	3	:	:	PUNCT
dti-2638	216	4	this	this	DET
dti-2638	216	5	research	research	NOUN
dti-2638	216	6	received	receive	VERB
dti-2638	216	7	no	no	DET
dti-2638	216	8	specific	specific	ADJ
dti-2638	216	9	grant	grant	NOUN
dti-2638	216	10	from	from	ADP
dti-2638	216	11	any	any	DET
dti-2638	216	12	funding	funding	NOUN
dti-2638	216	13	agency	agency	NOUN
dti-2638	216	14	in	in	ADP
dti-2638	216	15	the	the	DET
dti-2638	216	16	public	public	ADJ
dti-2638	216	17	,	,	PUNCT
dti-2638	216	18	commercial	commercial	ADJ
dti-2638	216	19	,	,	PUNCT
dti-2638	216	20	or	or	CCONJ
dti-2638	216	21	not	not	PART
dti-2638	216	22	-	-	PUNCT
dti-2638	216	23	for	for	ADP
dti-2638	216	24	-	-	PUNCT
dti-2638	216	25	profit	profit	NOUN
dti-2638	216	26	sectors	sector	NOUN
dti-2638	216	27	.	.	PUNCT
dti-2638	217	1	authors	author	NOUN
dti-2638	217	2	contribution	contribution	VERB
dti-2638	217	3	:	:	PUNCT
dti-2638	217	4	gg	gg	NOUN
dti-2638	217	5	:	:	PUNCT
dti-2638	217	6	carried	carry	VERB
dti-2638	217	7	out	out	ADP
dti-2638	217	8	experiments	experiment	NOUN
dti-2638	217	9	;	;	PUNCT
dti-2638	217	10	participated	participate	VERB
dti-2638	217	11	in	in	ADP
dti-2638	217	12	manuscript	manuscript	NOUN
dti-2638	217	13	preparation	preparation	NOUN
dti-2638	217	14	;	;	PUNCT
dti-2638	217	15	literature	literature	NOUN
dti-2638	217	16	survey	survey	NOUN
dti-2638	217	17	;	;	PUNCT
dti-2638	217	18	nh	nh	PROPN
dti-2638	217	19	and	and	CCONJ
dti-2638	217	20	bc	bc	PROPN
dti-2638	217	21	:	:	PUNCT
dti-2638	217	22	executed	execute	VERB
dti-2638	217	23	in	in	ADP
dti-2638	217	24	silico	silico	NOUN
dti-2638	217	25	part	part	NOUN
dti-2638	217	26	of	of	ADP
dti-2638	217	27	the	the	DET
dti-2638	217	28	study	study	NOUN
dti-2638	217	29	;	;	PUNCT
dti-2638	217	30	arranged	arrange	VERB
dti-2638	217	31	procurement	procurement	NOUN
dti-2638	217	32	of	of	ADP
dti-2638	217	33	test	test	NOUN
dti-2638	217	34	compounds	compound	NOUN
dti-2638	217	35	in	in	ADP
dti-2638	217	36	physical	physical	ADJ
dti-2638	217	37	form	form	NOUN
dti-2638	217	38	;	;	PUNCT
dti-2638	217	39	vk	vk	X
dti-2638	217	40	:	:	PUNCT
dti-2638	217	41	conceptualization	conceptualization	NOUN
dti-2638	217	42	,	,	PUNCT
dti-2638	217	43	data	datum	NOUN
dti-2638	217	44	analysis	analysis	NOUN
dti-2638	217	45	,	,	PUNCT
dti-2638	217	46	and	and	CCONJ
dti-2638	217	47	manuscript	manuscript	NOUN
dti-2638	217	48	preparation	preparation	NOUN
dti-2638	217	49	references	reference	NOUN
dti-2638	217	50	1	1	NUM
dti-2638	217	51	.	.	PUNCT
dti-2638	218	1	murray	murray	PROPN
dti-2638	218	2	cj	cj	PROPN
dti-2638	218	3	,	,	PUNCT
dti-2638	218	4	ikuta	ikuta	PROPN
dti-2638	218	5	ks	ks	PROPN
dti-2638	218	6	,	,	PUNCT
dti-2638	218	7	sharara	sharara	NOUN
dti-2638	218	8	f	f	X
dti-2638	218	9	,	,	PUNCT
dti-2638	218	10	et	et	PROPN
dti-2638	218	11	al	al	PROPN
dti-2638	218	12	;	;	PUNCT
dti-2638	218	13	antimicrobial	antimicrobial	ADJ
dti-2638	218	14	resistance	resistance	NOUN
dti-2638	218	15	collaborators	collaborator	NOUN
dti-2638	218	16	.	.	PUNCT
dti-2638	219	1	global	global	ADJ
dti-2638	219	2	burden	burden	NOUN
dti-2638	219	3	of	of	ADP
dti-2638	219	4	bacterial	bacterial	ADJ
dti-2638	219	5	antimicrobial	antimicrobial	ADJ
dti-2638	219	6	resistance	resistance	NOUN
dti-2638	219	7	in	in	ADP
dti-2638	219	8	2019	2019	NUM
dti-2638	219	9	:	:	PUNCT
dti-2638	219	10	a	a	DET
dti-2638	219	11	systematic	systematic	ADJ
dti-2638	219	12	analysis	analysis	NOUN
dti-2638	219	13	.	.	PUNCT
dti-2638	220	1	lancet	lancet	PROPN
dti-2638	220	2	.	.	PUNCT
dti-2638	221	1	2022;399(10325	2022;399(10325	NUM
dti-2638	221	2	):	):	PUNCT
dti-2638	221	3	629	629	NUM
dti-2638	221	4	-	-	SYM
dti-2638	221	5	655	655	NUM
dti-2638	221	6	.	.	PUNCT
dti-2638	222	1	crossref	crossref	PROPN
dti-2638	222	2	pubmed	pubmed	PROPN
dti-2638	222	3	2	2	PROPN
dti-2638	222	4	.	.	PUNCT
dti-2638	222	5	tacconelli	tacconelli	PROPN
dti-2638	222	6	e	e	PROPN
dti-2638	222	7	,	,	PUNCT
dti-2638	222	8	carrara	carrara	ADJ
dti-2638	222	9	e	e	NOUN
dti-2638	222	10	,	,	PUNCT
dti-2638	222	11	savoldi	savoldi	NOUN
dti-2638	222	12	a	a	PROPN
dti-2638	222	13	,	,	PUNCT
dti-2638	222	14	et	et	PROPN
dti-2638	222	15	al	al	PROPN
dti-2638	222	16	;	;	PUNCT
dti-2638	222	17	who	who	PRON
dti-2638	222	18	pathogens	pathogen	VERB
dti-2638	222	19	priority	priority	NOUN
dti-2638	222	20	list	list	NOUN
dti-2638	222	21	working	working	NOUN
dti-2638	222	22	group	group	NOUN
dti-2638	222	23	.	.	PUNCT
dti-2638	223	1	discovery	discovery	NOUN
dti-2638	223	2	,	,	PUNCT
dti-2638	223	3	research	research	NOUN
dti-2638	223	4	,	,	PUNCT
dti-2638	223	5	and	and	CCONJ
dti-2638	223	6	development	development	NOUN
dti-2638	223	7	of	of	ADP
dti-2638	223	8	new	new	ADJ
dti-2638	223	9	antibiotics	antibiotic	NOUN
dti-2638	223	10	:	:	PUNCT
dti-2638	223	11	the	the	DET
dti-2638	223	12	who	who	PRON
dti-2638	223	13	priority	priority	NOUN
dti-2638	223	14	list	list	NOUN
dti-2638	223	15	of	of	ADP
dti-2638	223	16	antibiotic	antibiotic	ADJ
dti-2638	223	17	-	-	PUNCT
dti-2638	223	18	resistant	resistant	ADJ
dti-2638	223	19	bacteria	bacteria	NOUN
dti-2638	223	20	and	and	CCONJ
dti-2638	223	21	tuberculosis	tuberculosis	NOUN
dti-2638	223	22	.	.	PUNCT
dti-2638	224	1	lancet	lancet	PROPN
dti-2638	224	2	infect	infect	PROPN
dti-2638	224	3	dis	dis	PROPN
dti-2638	224	4	.	.	PUNCT
dti-2638	225	1	2018;18(3):318	2018;18(3):318	PROPN
dti-2638	225	2	-	-	PUNCT
dti-2638	225	3	327	327	NUM
dti-2638	225	4	.	.	PUNCT
dti-2638	226	1	crossref	crossref	PROPN
dti-2638	226	2	pubmed	pubmed	PROPN
dti-2638	226	3	3	3	PROPN
dti-2638	226	4	.	.	PUNCT
dti-2638	227	1	singh	singh	PROPN
dti-2638	227	2	sb	sb	PROPN
dti-2638	227	3	,	,	PUNCT
dti-2638	227	4	barrett	barrett	PROPN
dti-2638	227	5	jf	jf	PROPN
dti-2638	227	6	.	.	PROPN
dti-2638	228	1	empirical	empirical	ADJ
dti-2638	228	2	antibacterial	antibacterial	ADJ
dti-2638	228	3	drug	drug	NOUN
dti-2638	228	4	discovery	discovery	NOUN
dti-2638	228	5	–	–	PUNCT
dti-2638	228	6	foundation	foundation	NOUN
dti-2638	228	7	in	in	ADP
dti-2638	228	8	natural	natural	ADJ
dti-2638	228	9	products	product	NOUN
dti-2638	228	10	.	.	PUNCT
dti-2638	229	1	biochem	biochem	PROPN
dti-2638	229	2	pharmacol	pharmacol	PROPN
dti-2638	229	3	.	.	PUNCT
dti-2638	230	1	2006;71(7	2006;71(7	NUM
dti-2638	230	2	):	):	PUNCT
dti-2638	230	3	1006	1006	NUM
dti-2638	230	4	-	-	SYM
dti-2638	230	5	1015	1015	NUM
dti-2638	230	6	.	.	PUNCT
dti-2638	231	1	crossref	crossref	PROPN
dti-2638	231	2	pubmed	pubmed	PROPN
dti-2638	231	3	4	4	PROPN
dti-2638	231	4	.	.	PUNCT
dti-2638	232	1	payne	payne	PROPN
dti-2638	232	2	dj	dj	PROPN
dti-2638	232	3	,	,	PUNCT
dti-2638	232	4	gwynn	gwynn	PROPN
dti-2638	232	5	mn	mn	PROPN
dti-2638	232	6	,	,	PUNCT
dti-2638	232	7	holmes	holmes	PROPN
dti-2638	232	8	dj	dj	PROPN
dti-2638	232	9	,	,	PUNCT
dti-2638	232	10	pompliano	pompliano	PROPN
dti-2638	232	11	dl	dl	PROPN
dti-2638	232	12	.	.	PUNCT
dti-2638	232	13	drugs	drug	NOUN
dti-2638	232	14	for	for	ADP
dti-2638	232	15	bad	bad	ADJ
dti-2638	232	16	bugs	bug	NOUN
dti-2638	232	17	:	:	PUNCT
dti-2638	232	18	confronting	confront	VERB
dti-2638	232	19	the	the	DET
dti-2638	232	20	challenges	challenge	NOUN
dti-2638	232	21	of	of	ADP
dti-2638	232	22	antibacterial	antibacterial	ADJ
dti-2638	232	23	discovery	discovery	NOUN
dti-2638	232	24	.	.	PUNCT
dti-2638	233	1	nat	nat	PROPN
dti-2638	233	2	rev	rev	VERB
dti-2638	233	3	drug	drug	NOUN
dti-2638	233	4	discov	discov	NOUN
dti-2638	233	5	.	.	PUNCT
dti-2638	234	1	2007;6(1):29	2007;6(1):29	NUM
dti-2638	234	2	-	-	SYM
dti-2638	234	3	40	40	NUM
dti-2638	234	4	.	.	PUNCT
dti-2638	235	1	crossref	crossref	PROPN
dti-2638	235	2	pubmed	pubmed	PROPN
dti-2638	235	3	5	5	PROPN
dti-2638	235	4	.	.	PUNCT
dti-2638	236	1	jaeger	jaeger	PROPN
dti-2638	236	2	t	t	PROPN
dti-2638	236	3	,	,	PUNCT
dti-2638	236	4	flohé	flohé	ADJ
dti-2638	236	5	l.	l.	PROPN
dti-2638	236	6	the	the	DET
dti-2638	236	7	thiol	thiol	NOUN
dti-2638	236	8	-	-	PUNCT
dti-2638	236	9	based	base	VERB
dti-2638	236	10	redox	redox	ADJ
dti-2638	236	11	networks	network	NOUN
dti-2638	236	12	of	of	ADP
dti-2638	236	13	pathogens	pathogen	NOUN
dti-2638	236	14	:	:	PUNCT
dti-2638	236	15	unexploited	unexploited	ADJ
dti-2638	236	16	targets	target	NOUN
dti-2638	236	17	in	in	ADP
dti-2638	236	18	the	the	DET
dti-2638	236	19	search	search	NOUN
dti-2638	236	20	for	for	ADP
dti-2638	236	21	new	new	ADJ
dti-2638	236	22	drugs	drug	NOUN
dti-2638	236	23	.	.	PUNCT
dti-2638	237	1	biofactors	biofactor	NOUN
dti-2638	237	2	.	.	PUNCT
dti-2638	238	1	2006;27(1	2006;27(1	NUM
dti-2638	238	2	-	-	PUNCT
dti-2638	238	3	4):109	4):109	NUM
dti-2638	238	4	-	-	PUNCT
dti-2638	238	5	120	120	NUM
dti-2638	238	6	.	.	PUNCT
dti-2638	239	1	crossref	crossref	PROPN
dti-2638	239	2	pubmed	pubmed	PROPN
dti-2638	239	3	6	6	NUM
dti-2638	239	4	.	.	PUNCT
dti-2638	239	5	ruparel	ruparel	PROPN
dti-2638	239	6	fj	fj	PROPN
dti-2638	239	7	,	,	PUNCT
dti-2638	239	8	shah	shah	PROPN
dti-2638	239	9	sk	sk	PROPN
dti-2638	239	10	,	,	PUNCT
dti-2638	239	11	patel	patel	PROPN
dti-2638	239	12	jh	jh	PROPN
dti-2638	239	13	,	,	PUNCT
dti-2638	239	14	thakkar	thakkar	PROPN
dti-2638	239	15	nr	nr	PROPN
dti-2638	239	16	,	,	PUNCT
dti-2638	239	17	gajera	gajera	PROPN
dti-2638	239	18	gn	gn	PROPN
dti-2638	239	19	,	,	PUNCT
dti-2638	239	20	kothari	kothari	PROPN
dti-2638	239	21	vo	vo	PROPN
dti-2638	239	22	.	.	PUNCT
dti-2638	240	1	network	network	NOUN
dti-2638	240	2	analysis	analysis	NOUN
dti-2638	240	3	for	for	ADP
dti-2638	240	4	identifying	identify	VERB
dti-2638	240	5	potential	potential	ADJ
dti-2638	240	6	anti	anti	ADJ
dti-2638	240	7	-	-	ADJ
dti-2638	240	8	virulence	virulence	ADJ
dti-2638	240	9	targets	target	NOUN
dti-2638	240	10	from	from	ADP
dti-2638	240	11	whole	whole	ADJ
dti-2638	240	12	transcriptome	transcriptome	NOUN
dti-2638	240	13	of	of	ADP
dti-2638	240	14	pseudomonas	pseudomona	NOUN
dti-2638	240	15	aeruginosa	aeruginosa	NOUN
dti-2638	240	16	and	and	CCONJ
dti-2638	240	17	staphylococcus	staphylococcus	NOUN
dti-2638	240	18	aureus	aureus	NOUN
dti-2638	240	19	exposed	expose	VERB
dti-2638	240	20	to	to	ADP
dti-2638	240	21	certain	certain	ADJ
dti-2638	240	22	anti	anti	ADJ
dti-2638	240	23	-	-	ADJ
dti-2638	240	24	pathogenic	pathogenic	ADJ
dti-2638	240	25	polyherbal	polyherbal	ADJ
dti-2638	240	26	formulations	formulation	NOUN
dti-2638	240	27	.	.	PUNCT
dti-2638	241	1	drug	drug	NOUN
dti-2638	241	2	target	target	NOUN
dti-2638	241	3	insights	insight	NOUN
dti-2638	241	4	.	.	PUNCT
dti-2638	242	1	2023;17:58	2023;17:58	NUM
dti-2638	242	2	-	-	SYM
dti-2638	242	3	69	69	NUM
dti-2638	242	4	.	.	PUNCT
dti-2638	243	1	crossref	crossref	PROPN
dti-2638	243	2	pubmed	pubmed	PROPN
dti-2638	243	3	7	7	PROPN
dti-2638	243	4	.	.	PUNCT
dti-2638	244	1	groleau	groleau	PROPN
dti-2638	244	2	mc	mc	PROPN
dti-2638	244	3	,	,	PUNCT
dti-2638	244	4	de	de	PROPN
dti-2638	244	5	oliveira	oliveira	PROPN
dti-2638	244	6	pereira	pereira	PROPN
dti-2638	244	7	t	t	PROPN
dti-2638	244	8	,	,	PUNCT
dti-2638	244	9	dekimpe	dekimpe	PROPN
dti-2638	244	10	v	v	PROPN
dti-2638	244	11	,	,	PUNCT
dti-2638	244	12	déziel	déziel	PROPN
dti-2638	244	13	e.	e.	PROPN
dti-2638	244	14	pqse	pqse	PROPN
dti-2638	244	15	is	be	AUX
dti-2638	244	16	essential	essential	ADJ
dti-2638	244	17	for	for	ADP
dti-2638	244	18	rhlr	rhlr	NOUN
dti-2638	244	19	-	-	PUNCT
dti-2638	244	20	dependent	dependent	ADJ
dti-2638	244	21	quorum	quorum	NOUN
dti-2638	244	22	sensing	sense	VERB
dti-2638	244	23	regulation	regulation	NOUN
dti-2638	244	24	in	in	ADP
dti-2638	244	25	pseudomonas	pseudomona	NOUN
dti-2638	244	26	aeruginosa	aeruginosa	NOUN
dti-2638	244	27	.	.	PUNCT
dti-2638	245	1	msystems	msystem	NOUN
dti-2638	245	2	.	.	PUNCT
dti-2638	246	1	2020;5(3):10	2020;5(3):10	NUM
dti-2638	246	2	-	-	SYM
dti-2638	246	3	128	128	NUM
dti-2638	246	4	.	.	PUNCT
dti-2638	247	1	crossref	crossref	PROPN
dti-2638	247	2	pubmed	pubmed	PROPN
dti-2638	247	3	8	8	PROPN
dti-2638	247	4	.	.	PUNCT
dti-2638	248	1	joshi	joshi	PROPN
dti-2638	248	2	c	c	PROPN
dti-2638	248	3	,	,	PUNCT
dti-2638	248	4	kothari	kothari	PROPN
dti-2638	248	5	v.	v.	ADP
dti-2638	248	6	bacterial	bacterial	ADJ
dti-2638	248	7	stress	stress	NOUN
dti-2638	248	8	-	-	PUNCT
dti-2638	248	9	response	response	NOUN
dti-2638	248	10	machinery	machinery	NOUN
dti-2638	248	11	as	as	ADP
dti-2638	248	12	a	a	DET
dti-2638	248	13	target	target	NOUN
dti-2638	248	14	for	for	ADP
dti-2638	248	15	next	next	ADJ
dti-2638	248	16	-	-	PUNCT
dti-2638	248	17	generation	generation	NOUN
dti-2638	248	18	antimicrobials	antimicrobial	NOUN
dti-2638	248	19	.	.	PUNCT
dti-2638	249	1	infect	infect	VERB
dti-2638	249	2	disord	disord	NOUN
dti-2638	249	3	drug	drug	NOUN
dti-2638	249	4	targets	target	NOUN
dti-2638	249	5	.	.	PUNCT
dti-2638	250	1	2022;22(6):e210322202493	2022;22(6):e210322202493	NUM
dti-2638	250	2	.	.	PUNCT
dti-2638	251	1	crossref	crossref	PROPN
dti-2638	251	2	pubmed	pubmed	PROPN
dti-2638	251	3	9	9	PROPN
dti-2638	251	4	.	.	PUNCT
dti-2638	252	1	porcheron	porcheron	PROPN
dti-2638	252	2	g	g	PROPN
dti-2638	252	3	,	,	PUNCT
dti-2638	252	4	dozois	dozois	ADJ
dti-2638	252	5	cm	cm	PROPN
dti-2638	252	6	.	.	PUNCT
dti-2638	253	1	interplay	interplay	NOUN
dti-2638	253	2	between	between	ADP
dti-2638	253	3	iron	iron	NOUN
dti-2638	253	4	homeostasis	homeostasis	NOUN
dti-2638	253	5	and	and	CCONJ
dti-2638	253	6	virulence	virulence	NOUN
dti-2638	253	7	:	:	PUNCT
dti-2638	253	8	fur	fur	NOUN
dti-2638	253	9	and	and	CCONJ
dti-2638	253	10	ryhb	ryhb	NOUN
dti-2638	253	11	as	as	ADP
dti-2638	253	12	major	major	ADJ
dti-2638	253	13	regulators	regulator	NOUN
dti-2638	253	14	of	of	ADP
dti-2638	253	15	bacterial	bacterial	ADJ
dti-2638	253	16	pathogenicity	pathogenicity	NOUN
dti-2638	253	17	.	.	PUNCT
dti-2638	254	1	vet	vet	NOUN
dti-2638	254	2	microbiol	microbiol	PROPN
dti-2638	254	3	.	.	PUNCT
dti-2638	255	1	2015;179(1	2015;179(1	NUM
dti-2638	255	2	-	-	PUNCT
dti-2638	255	3	2):2	2):2	NUM
dti-2638	255	4	-	-	SYM
dti-2638	255	5	14	14	NUM
dti-2638	255	6	.	.	PUNCT
dti-2638	256	1	crossref	crossref	PROPN
dti-2638	256	2	pubmed	pubmed	PROPN
dti-2638	256	3	10	10	PROPN
dti-2638	256	4	.	.	PUNCT
dti-2638	257	1	hofmann	hofmann	PROPN
dti-2638	257	2	l	l	PROPN
dti-2638	257	3	,	,	PUNCT
dti-2638	257	4	hirsch	hirsch	PROPN
dti-2638	257	5	m	m	PROPN
dti-2638	257	6	,	,	PUNCT
dti-2638	257	7	ruthstein	ruthstein	PROPN
dti-2638	257	8	s.	s.	PROPN
dti-2638	257	9	advances	advance	VERB
dti-2638	257	10	in	in	ADP
dti-2638	257	11	understanding	understanding	NOUN
dti-2638	257	12	of	of	ADP
dti-2638	257	13	the	the	DET
dti-2638	257	14	copper	copper	NOUN
dti-2638	257	15	homeostasis	homeostasis	NOUN
dti-2638	257	16	in	in	ADP
dti-2638	257	17	pseudomonas	pseudomona	NOUN
dti-2638	257	18	aeruginosa	aeruginosa	NOUN
dti-2638	257	19	.	.	PUNCT
dti-2638	258	1	int	int	PROPN
dti-2638	258	2	j	j	PROPN
dti-2638	258	3	mol	mol	ADP
dti-2638	258	4	sci	sci	PROPN
dti-2638	258	5	.	.	PUNCT
dti-2638	259	1	2021;22(4):2050	2021;22(4):2050	NUM
dti-2638	259	2	.	.	PUNCT
dti-2638	260	1	crossref	crossref	PROPN
dti-2638	260	2	pubmed	pubmed	PROPN
dti-2638	260	3	11	11	NUM
dti-2638	260	4	.	.	PUNCT
dti-2638	261	1	chen	chen	PROPN
dti-2638	261	2	h	h	PROPN
dti-2638	261	3	,	,	PUNCT
dti-2638	261	4	han	han	PROPN
dti-2638	261	5	j	j	PROPN
dti-2638	261	6	,	,	PUNCT
dti-2638	261	7	wang	wang	PROPN
dti-2638	261	8	l.	l.	PROPN
dti-2638	261	9	diels	diels	PROPN
dti-2638	261	10	-	-	PUNCT
dti-2638	261	11	alder	alder	NOUN
dti-2638	261	12	cycloadditions	cycloaddition	NOUN
dti-2638	261	13	of	of	ADP
dti-2638	261	14	n	n	NOUN
dti-2638	261	15	-	-	PUNCT
dti-2638	261	16	arylpyrroles	arylpyrrole	NOUN
dti-2638	261	17	via	via	ADP
dti-2638	261	18	aryne	aryne	NOUN
dti-2638	261	19	intermediates	intermediate	NOUN
dti-2638	261	20	using	use	VERB
dti-2638	261	21	diaryliodonium	diaryliodonium	ADJ
dti-2638	261	22	salts	salt	NOUN
dti-2638	261	23	.	.	PUNCT
dti-2638	262	1	beilstein	beilstein	ADJ
dti-2638	262	2	j	j	PROPN
dti-2638	262	3	org	org	PROPN
dti-2638	262	4	chem	chem	NOUN
dti-2638	262	5	.	.	PUNCT
dti-2638	263	1	2018;14(1):354	2018;14(1):354	NUM
dti-2638	263	2	-	-	SYM
dti-2638	263	3	363	363	NUM
dti-2638	263	4	.	.	PUNCT
dti-2638	264	1	crossref	crossref	PROPN
dti-2638	264	2	pubmed	pubmed	PROPN
dti-2638	264	3	12	12	NUM
dti-2638	264	4	.	.	PUNCT
dti-2638	265	1	kamal	kamal	PROPN
dti-2638	265	2	aa	aa	PROPN
dti-2638	265	3	,	,	PUNCT
dti-2638	265	4	maurer	maurer	PROPN
dti-2638	265	5	ck	ck	PROPN
dti-2638	265	6	,	,	PUNCT
dti-2638	265	7	allegretta	allegretta	NOUN
dti-2638	265	8	g	g	NOUN
dti-2638	265	9	,	,	PUNCT
dti-2638	265	10	haupenthal	haupenthal	PROPN
dti-2638	265	11	j	j	PROPN
dti-2638	265	12	,	,	PUNCT
dti-2638	265	13	empting	empting	PROPN
dti-2638	265	14	m	m	PROPN
dti-2638	265	15	,	,	PUNCT
dti-2638	265	16	hartmann	hartmann	PROPN
dti-2638	265	17	rw	rw	PROPN
dti-2638	265	18	.	.	PUNCT
dti-2638	265	19	quorum	quorum	PROPN
dti-2638	265	20	sensing	sense	VERB
dti-2638	265	21	inhibitors	inhibitor	NOUN
dti-2638	265	22	as	as	ADP
dti-2638	265	23	pathoblockers	pathoblocker	NOUN
dti-2638	265	24	for	for	ADP
dti-2638	265	25	pseudomonas	pseudomona	NOUN
dti-2638	265	26	aeruginosa	aeruginosa	NOUN
dti-2638	265	27	infections	infection	NOUN
dti-2638	265	28	:	:	PUNCT
dti-2638	265	29	a	a	DET
dti-2638	265	30	new	new	ADJ
dti-2638	265	31	concept	concept	NOUN
dti-2638	265	32	in	in	ADP
dti-2638	265	33	anti	anti	ADJ
dti-2638	265	34	-	-	ADJ
dti-2638	265	35	infective	infective	ADJ
dti-2638	265	36	drug	drug	NOUN
dti-2638	265	37	discovery	discovery	NOUN
dti-2638	265	38	.	.	PUNCT
dti-2638	266	1	antibacterials	antibacterial	NOUN
dti-2638	266	2	.	.	PUNCT
dti-2638	267	1	2018;ii:185	2018;ii:185	NUM
dti-2638	267	2	-	-	SYM
dti-2638	267	3	210	210	NUM
dti-2638	267	4	.	.	PUNCT
dti-2638	268	1	crossref	crossref	PROPN
dti-2638	268	2	13	13	NUM
dti-2638	268	3	.	.	PUNCT
dti-2638	269	1	bonvicini	bonvicini	PROPN
dti-2638	269	2	f	f	PROPN
dti-2638	269	3	,	,	PUNCT
dti-2638	269	4	mandrone	mandrone	PROPN
dti-2638	269	5	m	m	PROPN
dti-2638	269	6	,	,	PUNCT
dti-2638	269	7	cosa	cosa	PROPN
dti-2638	269	8	s.	s.	PROPN
dti-2638	269	9	editorial	editorial	PROPN
dti-2638	269	10	:	:	PUNCT
dti-2638	269	11	pathoblockers	pathoblocker	NOUN
dti-2638	269	12	and	and	CCONJ
dti-2638	269	13	antivirulence	antivirulence	NOUN
dti-2638	269	14	agents	agent	NOUN
dti-2638	269	15	of	of	ADP
dti-2638	269	16	plant	plant	NOUN
dti-2638	269	17	-	-	PUNCT
dti-2638	269	18	origin	origin	NOUN
dti-2638	269	19	for	for	ADP
dti-2638	269	20	the	the	DET
dti-2638	269	21	management	management	NOUN
dti-2638	269	22	of	of	ADP
dti-2638	269	23	multidrug	multidrug	NOUN
dti-2638	269	24	resistant	resistant	ADJ
dti-2638	269	25	pathogens	pathogen	NOUN
dti-2638	269	26	.	.	PUNCT
dti-2638	270	1	front	front	ADJ
dti-2638	270	2	microbiol	microbiol	NOUN
dti-2638	270	3	.	.	PUNCT
dti-2638	271	1	2023;14:1201495	2023;14:1201495	NUM
dti-2638	271	2	.	.	PUNCT
dti-2638	272	1	crossref	crossref	PROPN
dti-2638	272	2	pubmed	pubmed	PROPN
dti-2638	272	3	14	14	PROPN
dti-2638	272	4	.	.	PUNCT
dti-2638	273	1	huang	huang	PROPN
dti-2638	273	2	y	y	PROPN
dti-2638	273	3	,	,	PUNCT
dti-2638	273	4	chen	chen	PROPN
dti-2638	273	5	y	y	PROPN
dti-2638	273	6	,	,	PUNCT
dti-2638	273	7	zhang	zhang	PROPN
dti-2638	273	8	lh	lh	PROPN
dti-2638	273	9	.	.	PUNCT
dti-2638	274	1	the	the	DET
dti-2638	274	2	roles	role	NOUN
dti-2638	274	3	of	of	ADP
dti-2638	274	4	microbial	microbial	ADJ
dti-2638	274	5	cell	cell	NOUN
dti-2638	274	6	-	-	PUNCT
dti-2638	274	7	cell	cell	NOUN
dti-2638	274	8	chemical	chemical	NOUN
dti-2638	274	9	communication	communication	NOUN
dti-2638	274	10	systems	system	NOUN
dti-2638	274	11	in	in	ADP
dti-2638	274	12	the	the	DET
dti-2638	274	13	modulation	modulation	NOUN
dti-2638	274	14	of	of	ADP
dti-2638	274	15	antimicrobial	antimicrobial	ADJ
dti-2638	274	16	resistance	resistance	NOUN
dti-2638	274	17	.	.	PUNCT
dti-2638	275	1	antibiotics	antibiotic	NOUN
dti-2638	275	2	(	(	PUNCT
dti-2638	275	3	basel	basel	PROPN
dti-2638	275	4	)	)	PUNCT
dti-2638	275	5	.	.	PUNCT
dti-2638	276	1	2020;9(11):779	2020;9(11):779	PROPN
dti-2638	276	2	.	.	PUNCT
dti-2638	277	1	crossref	crossref	PROPN
dti-2638	277	2	pubmed	pubmed	PROPN
dti-2638	277	3	15	15	PROPN
dti-2638	277	4	.	.	PUNCT
dti-2638	278	1	nandi	nandi	PROPN
dti-2638	278	2	s.	s.	PROPN
dti-2638	278	3	recent	recent	ADJ
dti-2638	278	4	advances	advance	NOUN
dti-2638	278	5	in	in	ADP
dti-2638	278	6	ligand	ligand	NOUN
dti-2638	278	7	and	and	CCONJ
dti-2638	278	8	structure	structure	NOUN
dti-2638	278	9	based	base	VERB
dti-2638	278	10	screening	screening	NOUN
dti-2638	278	11	of	of	ADP
dti-2638	278	12	potent	potent	ADJ
dti-2638	278	13	quorum	quorum	NOUN
dti-2638	278	14	sensing	sense	VERB
dti-2638	278	15	inhibitors	inhibitor	NOUN
dti-2638	278	16	against	against	ADP
dti-2638	278	17	antibiotic	antibiotic	ADJ
dti-2638	278	18	resistance	resistance	NOUN
dti-2638	278	19	induced	induce	VERB
dti-2638	278	20	bacterial	bacterial	ADJ
dti-2638	278	21	virulence	virulence	NOUN
dti-2638	278	22	.	.	PUNCT
dti-2638	279	1	recent	recent	ADJ
dti-2638	279	2	pat	pat	PROPN
dti-2638	279	3	biotechnol	biotechnol	NOUN
dti-2638	279	4	.	.	PUNCT
dti-2638	280	1	2016;10(2):195	2016;10(2):195	NUM
dti-2638	280	2	-	-	PUNCT
dti-2638	280	3	216	216	NUM
dti-2638	280	4	.	.	PUNCT
dti-2638	281	1	crossref	crossref	PROPN
dti-2638	281	2	pubmed	pubmed	PROPN
dti-2638	281	3	16	16	NUM
dti-2638	281	4	.	.	PUNCT
dti-2638	282	1	kumar	kumar	PROPN
dti-2638	282	2	m	m	PROPN
dti-2638	282	3	,	,	PUNCT
dti-2638	282	4	saxena	saxena	PROPN
dti-2638	282	5	m	m	PROPN
dti-2638	282	6	,	,	PUNCT
dti-2638	282	7	saxena	saxena	PROPN
dti-2638	282	8	ak	ak	PROPN
dti-2638	282	9	,	,	PUNCT
dti-2638	282	10	nandi	nandi	PROPN
dti-2638	282	11	s.	s.	PROPN
dti-2638	282	12	recent	recent	ADJ
dti-2638	282	13	breakthroughs	breakthrough	NOUN
dti-2638	282	14	in	in	ADP
dti-2638	282	15	various	various	ADJ
dti-2638	282	16	antimicrobial	antimicrobial	ADJ
dti-2638	282	17	resistance	resistance	NOUN
dti-2638	282	18	induced	induce	VERB
dti-2638	282	19	quorum	quorum	NOUN
dti-2638	282	20	sensing	sense	VERB
dti-2638	282	21	biosynthetic	biosynthetic	ADJ
dti-2638	282	22	pathway	pathway	NOUN
dti-2638	282	23	mediated	mediate	VERB
dti-2638	282	24	targets	target	NOUN
dti-2638	282	25	and	and	CCONJ
dti-2638	282	26	design	design	NOUN
dti-2638	282	27	of	of	ADP
dti-2638	282	28	their	their	PRON
dti-2638	282	29	inhibitors	inhibitor	NOUN
dti-2638	282	30	.	.	PUNCT
dti-2638	283	1	comb	comb	VERB
dti-2638	283	2	chem	chem	NOUN
dti-2638	283	3	high	high	ADJ
dti-2638	283	4	throughput	throughput	NOUN
dti-2638	283	5	screen	screen	NOUN
dti-2638	283	6	.	.	PUNCT
dti-2638	284	1	2020;23(6):458	2020;23(6):458	NUM
dti-2638	284	2	-	-	PUNCT
dti-2638	284	3	476	476	NUM
dti-2638	284	4	.	.	PUNCT
dti-2638	285	1	crossref	crossref	PROPN
dti-2638	285	2	pubmed	pubmed	PROPN
dti-2638	285	3	17	17	NUM
dti-2638	285	4	.	.	PUNCT
dti-2638	286	1	abisado	abisado	PROPN
dti-2638	286	2	rg	rg	PROPN
dti-2638	286	3	,	,	PUNCT
dti-2638	286	4	benomar	benomar	PROPN
dti-2638	286	5	s	s	PROPN
dti-2638	286	6	,	,	PUNCT
dti-2638	286	7	klaus	klaus	PROPN
dti-2638	286	8	jr	jr	PROPN
dti-2638	286	9	,	,	PUNCT
dti-2638	286	10	dandekar	dandekar	PROPN
dti-2638	286	11	aa	aa	PROPN
dti-2638	286	12	,	,	PUNCT
dti-2638	286	13	chandler	chandler	PROPN
dti-2638	286	14	jr	jr	PROPN
dti-2638	286	15	.	.	PROPN
dti-2638	287	1	bacterial	bacterial	ADJ
dti-2638	287	2	quorum	quorum	NOUN
dti-2638	287	3	sensing	sense	VERB
dti-2638	287	4	and	and	CCONJ
dti-2638	287	5	microbial	microbial	ADJ
dti-2638	287	6	community	community	NOUN
dti-2638	287	7	interactions	interaction	NOUN
dti-2638	287	8	.	.	PUNCT
dti-2638	288	1	mbio	mbio	NOUN
dti-2638	288	2	.	.	PUNCT
dti-2638	289	1	2018;9(3):10	2018;9(3):10	NUM
dti-2638	289	2	-	-	SYM
dti-2638	289	3	128	128	NUM
dti-2638	289	4	.	.	PUNCT
dti-2638	290	1	crossref	crossref	PROPN
dti-2638	290	2	pubmed	pubmed	PROPN
dti-2638	290	3	18	18	NUM
dti-2638	290	4	.	.	PUNCT
dti-2638	290	5	della	della	PROPN
dti-2638	290	6	sala	sala	PROPN
dti-2638	290	7	g	g	PROPN
dti-2638	290	8	,	,	PUNCT
dti-2638	290	9	teta	teta	PROPN
dti-2638	290	10	r	r	PROPN
dti-2638	290	11	,	,	PUNCT
dti-2638	290	12	esposito	esposito	PROPN
dti-2638	290	13	g	g	PROPN
dti-2638	290	14	,	,	PUNCT
dti-2638	290	15	costantino	costantino	PROPN
dti-2638	290	16	v.	v.	ADP
dti-2638	290	17	the	the	DET
dti-2638	290	18	chemical	chemical	NOUN
dti-2638	290	19	language	language	NOUN
dti-2638	290	20	of	of	ADP
dti-2638	290	21	gram	gram	NOUN
dti-2638	290	22	-	-	PUNCT
dti-2638	290	23	negative	negative	ADJ
dti-2638	290	24	bacteria	bacteria	NOUN
dti-2638	290	25	.	.	PUNCT
dti-2638	291	1	inquorum	inquorum	PROPN
dti-2638	291	2	sensing	sensing	NOUN
dti-2638	291	3	.	.	PUNCT
dti-2638	292	1	academic	academic	ADJ
dti-2638	292	2	press	press	NOUN
dti-2638	292	3	;	;	PUNCT
dti-2638	292	4	2019:3	2019:3	NUM
dti-2638	292	5	-	-	SYM
dti-2638	292	6	28	28	NUM
dti-2638	292	7	.	.	PUNCT
dti-2638	293	1	crossref	crossref	PROPN
dti-2638	293	2	.	.	PUNCT
dti-2638	294	1	19	19	NUM
dti-2638	294	2	.	.	PUNCT
dti-2638	294	3	kanak	kanak	PROPN
dti-2638	294	4	kr	kr	PROPN
dti-2638	294	5	,	,	PUNCT
dti-2638	294	6	dass	dass	PROPN
dti-2638	294	7	rs	rs	PROPN
dti-2638	294	8	,	,	PUNCT
dti-2638	294	9	pan	pan	PROPN
dti-2638	294	10	a.	a.	NOUN
dti-2638	294	11	anti	anti	ADJ
dti-2638	294	12	-	-	ADJ
dti-2638	294	13	quorum	quorum	ADJ
dti-2638	294	14	sensing	sense	VERB
dti-2638	294	15	potential	potential	NOUN
dti-2638	294	16	of	of	ADP
dti-2638	294	17	selenium	selenium	NOUN
dti-2638	294	18	nanoparticles	nanoparticle	NOUN
dti-2638	294	19	against	against	ADP
dti-2638	294	20	lasi	lasi	PROPN
dti-2638	294	21	/	/	SYM
dti-2638	294	22	r	r	PROPN
dti-2638	294	23	,	,	PUNCT
dti-2638	294	24	rhli	rhli	NOUN
dti-2638	294	25	/	/	SYM
dti-2638	294	26	r	r	NOUN
dti-2638	294	27	,	,	PUNCT
dti-2638	294	28	and	and	CCONJ
dti-2638	294	29	pqs	pqs	PROPN
dti-2638	294	30	/	/	SYM
dti-2638	294	31	mvfr	mvfr	NOUN
dti-2638	294	32	in	in	ADP
dti-2638	294	33	pseudomonas	pseudomona	NOUN
dti-2638	294	34	aeruginosa	aeruginosa	NOUN
dti-2638	294	35	:	:	PUNCT
dti-2638	294	36	a	a	DET
dti-2638	294	37	molecular	molecular	ADJ
dti-2638	294	38	docking	docking	NOUN
dti-2638	294	39	approach	approach	NOUN
dti-2638	294	40	.	.	PUNCT
dti-2638	295	1	front	front	NOUN
dti-2638	295	2	mol	mol	ADP
dti-2638	295	3	biosci	biosci	PROPN
dti-2638	295	4	.	.	PUNCT
dti-2638	296	1	2023	2023	NUM
dti-2638	296	2	aug	aug	NOUN
dti-2638	296	3	10;10:1203672	10;10:1203672	NUM
dti-2638	296	4	.	.	PUNCT
dti-2638	297	1	crossref	crossref	PROPN
dti-2638	297	2	pubmed	pubmed	PROPN
dti-2638	297	3	20	20	PROPN
dti-2638	297	4	.	.	PUNCT
dti-2638	298	1	kostylev	kostylev	PROPN
dti-2638	298	2	m	m	PROPN
dti-2638	298	3	,	,	PUNCT
dti-2638	298	4	kim	kim	PROPN
dti-2638	298	5	dy	dy	PROPN
dti-2638	298	6	,	,	PUNCT
dti-2638	298	7	smalley	smalley	PROPN
dti-2638	298	8	ne	ne	PROPN
dti-2638	298	9	,	,	PUNCT
dti-2638	298	10	salukhe	salukhe	VERB
dti-2638	298	11	i	i	PRON
dti-2638	298	12	,	,	PUNCT
dti-2638	298	13	greenberg	greenberg	PROPN
dti-2638	298	14	ep	ep	PROPN
dti-2638	298	15	,	,	PUNCT
dti-2638	298	16	dandekar	dandekar	PROPN
dti-2638	298	17	aa	aa	PROPN
dti-2638	298	18	.	.	PUNCT
dti-2638	299	1	evolution	evolution	NOUN
dti-2638	299	2	of	of	ADP
dti-2638	299	3	the	the	DET
dti-2638	299	4	pseudomonas	pseudomona	NOUN
dti-2638	299	5	aeruginosa	aeruginosa	NOUN
dti-2638	299	6	quorum	quorum	ADV
dti-2638	299	7	-	-	PUNCT
dti-2638	299	8	sensing	sense	VERB
dti-2638	299	9	hierarchy	hierarchy	NOUN
dti-2638	299	10	.	.	PUNCT
dti-2638	300	1	proc	proc	PROPN
dti-2638	300	2	natl	natl	PROPN
dti-2638	300	3	acad	acad	PROPN
dti-2638	300	4	sci	sci	PROPN
dti-2638	300	5	usa	usa	PROPN
dti-2638	300	6	.	.	PROPN
dti-2638	300	7	2019;116(14):7027	2019;116(14):7027	NUM
dti-2638	300	8	-	-	SYM
dti-2638	300	9	7032	7032	NUM
dti-2638	300	10	.	.	PUNCT
dti-2638	301	1	crossref	crossref	PROPN
dti-2638	301	2	pubmed	pubmed	PROPN
dti-2638	301	3	21	21	NUM
dti-2638	301	4	.	.	PUNCT
dti-2638	302	1	schuster	schuster	PROPN
dti-2638	302	2	m	m	PROPN
dti-2638	302	3	,	,	PUNCT
dti-2638	302	4	urbanowski	urbanowski	ADJ
dti-2638	302	5	ml	ml	NOUN
dti-2638	302	6	,	,	PUNCT
dti-2638	302	7	greenberg	greenberg	PROPN
dti-2638	302	8	ep	ep	PROPN
dti-2638	302	9	.	.	PUNCT
dti-2638	303	1	promoter	promoter	PROPN
dti-2638	303	2	specificity	specificity	NOUN
dti-2638	303	3	in	in	ADP
dti-2638	303	4	pseudomonas	pseudomona	NOUN
dti-2638	303	5	aeruginosa	aeruginosa	NOUN
dti-2638	303	6	quorum	quorum	NOUN
dti-2638	303	7	sensing	sensing	NOUN
dti-2638	303	8	revealed	reveal	VERB
dti-2638	303	9	by	by	ADP
dti-2638	303	10	dna	dna	NOUN
dti-2638	303	11	binding	bind	VERB
dti-2638	303	12	of	of	ADP
dti-2638	303	13	purified	purified	ADJ
dti-2638	303	14	lasr	lasr	PROPN
dti-2638	303	15	.	.	PUNCT
dti-2638	304	1	proc	proc	PROPN
dti-2638	304	2	natl	natl	PROPN
dti-2638	304	3	acad	acad	PROPN
dti-2638	304	4	sci	sci	PROPN
dti-2638	304	5	usa	usa	PROPN
dti-2638	304	6	.	.	PROPN
dti-2638	304	7	2004	2004	NUM
dti-2638	304	8	;	;	PUNCT
dti-2638	305	1	101(45):15833	101(45):15833	NUM
dti-2638	305	2	-	-	SYM
dti-2638	305	3	15839	15839	NUM
dti-2638	305	4	.	.	PUNCT
dti-2638	306	1	crossref	crossref	PROPN
dti-2638	306	2	pubmed	pubmed	PROPN
dti-2638	306	3	22	22	NUM
dti-2638	306	4	.	.	PUNCT
dti-2638	307	1	maddocks	maddocks	PROPN
dti-2638	307	2	se	se	PROPN
dti-2638	307	3	.	.	PUNCT
dti-2638	308	1	novel	novel	ADJ
dti-2638	308	2	targets	target	NOUN
dti-2638	308	3	of	of	ADP
dti-2638	308	4	antimicrobial	antimicrobial	ADJ
dti-2638	308	5	therapies	therapy	NOUN
dti-2638	308	6	.	.	PUNCT
dti-2638	309	1	microbiol	microbiol	PROPN
dti-2638	309	2	spectr	spectr	PROPN
dti-2638	309	3	.	.	PUNCT
dti-2638	310	1	2016;4(2):10	2016;4(2):10	NUM
dti-2638	310	2	-	-	SYM
dti-2638	310	3	128	128	NUM
dti-2638	310	4	.	.	PUNCT
dti-2638	311	1	crossref	crossref	PROPN
dti-2638	311	2	pubmed	pubmed	PROPN
dti-2638	311	3	23	23	NUM
dti-2638	311	4	.	.	PUNCT
dti-2638	312	1	haque	haque	PROPN
dti-2638	312	2	s	s	PROPN
dti-2638	312	3	,	,	PUNCT
dti-2638	312	4	ahmad	ahmad	PROPN
dti-2638	312	5	f	f	PROPN
dti-2638	312	6	,	,	PUNCT
dti-2638	312	7	dar	dar	PROPN
dti-2638	312	8	sa	sa	PROPN
dti-2638	312	9	,	,	PUNCT
dti-2638	312	10	et	et	PROPN
dti-2638	312	11	al	al	PROPN
dti-2638	312	12	.	.	PUNCT
dti-2638	313	1	developments	development	NOUN
dti-2638	313	2	in	in	ADP
dti-2638	313	3	strategies	strategy	NOUN
dti-2638	313	4	for	for	ADP
dti-2638	313	5	quorum	quorum	NOUN
dti-2638	313	6	sensing	sense	VERB
dti-2638	313	7	virulence	virulence	NOUN
dti-2638	313	8	factor	factor	NOUN
dti-2638	313	9	inhibition	inhibition	NOUN
dti-2638	313	10	to	to	AUX
dti-2638	313	11	combat	combat	VERB
dti-2638	313	12	bacterial	bacterial	ADJ
dti-2638	313	13	drug	drug	NOUN
dti-2638	313	14	resistance	resistance	NOUN
dti-2638	313	15	.	.	PUNCT
dti-2638	314	1	microb	microb	PROPN
dti-2638	314	2	pathog	pathog	PROPN
dti-2638	314	3	.	.	PUNCT
dti-2638	315	1	2018;121:293	2018;121:293	NUM
dti-2638	315	2	-	-	SYM
dti-2638	315	3	302	302	NUM
dti-2638	315	4	.	.	PUNCT
dti-2638	316	1	crossref	crossref	PROPN
dti-2638	316	2	pubmed	pubmed	PROPN
dti-2638	316	3	24	24	NUM
dti-2638	316	4	.	.	PUNCT
dti-2638	317	1	geske	geske	PROPN
dti-2638	317	2	gd	gd	PROPN
dti-2638	317	3	,	,	PUNCT
dti-2638	317	4	o’neill	o’neill	PROPN
dti-2638	317	5	jc	jc	PROPN
dti-2638	317	6	,	,	PUNCT
dti-2638	317	7	blackwell	blackwell	VERB
dti-2638	317	8	he	he	PRON
dti-2638	317	9	.	.	PUNCT
dti-2638	318	1	expanding	expand	VERB
dti-2638	318	2	dialogues	dialogue	NOUN
dti-2638	318	3	:	:	PUNCT
dti-2638	318	4	from	from	ADP
dti-2638	318	5	natural	natural	ADJ
dti-2638	318	6	autoinducers	autoinducer	NOUN
dti-2638	318	7	to	to	ADP
dti-2638	318	8	non	non	ADJ
dti-2638	318	9	-	-	ADJ
dti-2638	318	10	natural	natural	ADJ
dti-2638	318	11	analogues	analogue	NOUN
dti-2638	318	12	that	that	PRON
dti-2638	318	13	modulate	modulate	VERB
dti-2638	318	14	quorum	quorum	NOUN
dti-2638	318	15	sensing	sense	VERB
dti-2638	318	16	in	in	ADP
dti-2638	318	17	gram	gram	NOUN
dti-2638	318	18	-	-	PUNCT
dti-2638	318	19	negative	negative	ADJ
dti-2638	318	20	bacteria	bacteria	NOUN
dti-2638	318	21	.	.	PUNCT
dti-2638	319	1	chem	chem	PROPN
dti-2638	319	2	soc	soc	NOUN
dti-2638	319	3	rev	rev	VERB
dti-2638	319	4	.	.	PUNCT
dti-2638	320	1	2008;37(7):1432	2008;37(7):1432	NUM
dti-2638	320	2	-	-	SYM
dti-2638	320	3	1447	1447	NUM
dti-2638	320	4	.	.	PUNCT
dti-2638	321	1	crossref	crossref	PROPN
dti-2638	321	2	pubmed	pubmed	PROPN
dti-2638	321	3	25	25	NUM
dti-2638	321	4	.	.	PUNCT
dti-2638	321	5	packiavathy	packiavathy	ADJ
dti-2638	321	6	iasv	iasv	NOUN
dti-2638	321	7	,	,	PUNCT
dti-2638	321	8	kannappan	kannappan	NOUN
dti-2638	321	9	a	a	PRON
dti-2638	321	10	,	,	PUNCT
dti-2638	321	11	thiyagarajan	thiyagarajan	NOUN
dti-2638	321	12	s	s	PROPN
dti-2638	321	13	,	,	PUNCT
dti-2638	321	14	et	et	PROPN
dti-2638	321	15	al	al	PROPN
dti-2638	321	16	.	.	PROPN
dti-2638	321	17	ahllactonase	ahllactonase	PROPN
dti-2638	321	18	producing	produce	VERB
dti-2638	321	19	psychrobacter	psychrobacter	NOUN
dti-2638	321	20	sp	sp	NOUN
dti-2638	321	21	.	.	PROPN
dti-2638	322	1	from	from	ADP
dti-2638	322	2	palk	palk	PROPN
dti-2638	322	3	bay	bay	PROPN
dti-2638	322	4	sediment	sediment	NOUN
dti-2638	322	5	mitigates	mitigate	VERB
dti-2638	322	6	quorum	quorum	VERB
dti-2638	322	7	sensing	sensing	NOUN
dti-2638	322	8	-	-	PUNCT
dti-2638	322	9	mediated	mediate	VERB
dti-2638	322	10	virulence	virulence	NOUN
dti-2638	322	11	production	production	NOUN
dti-2638	322	12	in	in	ADP
dti-2638	322	13	gram	gram	NOUN
dti-2638	322	14	negative	negative	ADJ
dti-2638	322	15	bacterial	bacterial	ADJ
dti-2638	322	16	pathogens	pathogen	NOUN
dti-2638	322	17	.	.	PUNCT
dti-2638	323	1	front	front	ADJ
dti-2638	323	2	microbiol	microbiol	PROPN
dti-2638	323	3	.	.	PUNCT
dti-2638	324	1	2021;12	2021;12	NUM
dti-2638	324	2	:	:	PUNCT
dti-2638	324	3	634593	634593	NUM
dti-2638	324	4	.	.	PUNCT
dti-2638	325	1	crossref	crossref	PROPN
dti-2638	325	2	pubmed	pubmed	PROPN
dti-2638	325	3	26	26	NUM
dti-2638	325	4	.	.	PUNCT
dti-2638	326	1	poole	poole	PROPN
dti-2638	326	2	k.	k.	PROPN
dti-2638	326	3	stress	stress	PROPN
dti-2638	326	4	responses	response	NOUN
dti-2638	326	5	as	as	ADP
dti-2638	326	6	determinants	determinant	NOUN
dti-2638	326	7	of	of	ADP
dti-2638	326	8	antimicrobial	antimicrobial	ADJ
dti-2638	326	9	resistance	resistance	NOUN
dti-2638	326	10	in	in	ADP
dti-2638	326	11	pseudomonas	pseudomona	NOUN
dti-2638	326	12	aeruginosa	aeruginosa	NOUN
dti-2638	326	13	:	:	PUNCT
dti-2638	326	14	multidrug	multidrug	NOUN
dti-2638	326	15	efflux	efflux	NOUN
dti-2638	326	16	and	and	CCONJ
dti-2638	326	17	more	more	ADJ
dti-2638	326	18	.	.	PUNCT
dti-2638	327	1	can	can	AUX
dti-2638	327	2	j	j	PROPN
dti-2638	327	3	microbiol	microbiol	PROPN
dti-2638	327	4	.	.	PUNCT
dti-2638	328	1	2014;60(12):783	2014;60(12):783	PROPN
dti-2638	328	2	-	-	SYM
dti-2638	328	3	791	791	NUM
dti-2638	328	4	.	.	PUNCT
dti-2638	329	1	crossref	crossref	PROPN
dti-2638	329	2	pubmed	pubmed	PROPN
dti-2638	329	3	27	27	NUM
dti-2638	329	4	.	.	PUNCT
dti-2638	330	1	joshi	joshi	PROPN
dti-2638	330	2	c	c	PROPN
dti-2638	330	3	,	,	PUNCT
dti-2638	330	4	patel	patel	PROPN
dti-2638	330	5	p	p	NOUN
dti-2638	330	6	,	,	PUNCT
dti-2638	330	7	palep	palep	VERB
dti-2638	330	8	h	h	NOUN
dti-2638	330	9	,	,	PUNCT
dti-2638	330	10	kothari	kothari	PROPN
dti-2638	330	11	v.	v.	ADP
dti-2638	330	12	validation	validation	NOUN
dti-2638	330	13	of	of	ADP
dti-2638	330	14	the	the	DET
dti-2638	330	15	antiinfective	antiinfective	ADJ
dti-2638	330	16	potential	potential	NOUN
dti-2638	330	17	of	of	ADP
dti-2638	330	18	a	a	DET
dti-2638	330	19	polyherbal	polyherbal	ADJ
dti-2638	330	20	‘	'	PUNCT
dti-2638	330	21	panchvalkal	panchvalkal	ADJ
dti-2638	330	22	’	'	PUNCT
dti-2638	330	23	preparation	preparation	NOUN
dti-2638	330	24	,	,	PUNCT
dti-2638	330	25	and	and	CCONJ
dti-2638	330	26	elucidation	elucidation	NOUN
dti-2638	330	27	of	of	ADP
dti-2638	330	28	the	the	DET
dti-2638	330	29	molecular	molecular	ADJ
dti-2638	330	30	basis	basis	NOUN
dti-2638	330	31	underlining	underline	VERB
dti-2638	330	32	its	its	PRON
dti-2638	330	33	efficacy	efficacy	NOUN
dti-2638	330	34	against	against	ADP
dti-2638	330	35	pseudomonas	pseudomona	NOUN
dti-2638	330	36	aeruginosa	aeruginosa	NOUN
dti-2638	330	37	.	.	PUNCT
dti-2638	331	1	bmc	bmc	PROPN
dti-2638	331	2	complement	complement	PROPN
dti-2638	331	3	altern	altern	NOUN
dti-2638	331	4	med	me	VERB
dti-2638	331	5	.	.	PUNCT
dti-2638	332	1	2019;19(1):1	2019;19(1):1	NUM
dti-2638	332	2	-	-	SYM
dti-2638	332	3	5	5	NUM
dti-2638	332	4	.	.	PUNCT
dti-2638	332	5	crossref	crossref	PROPN
dti-2638	332	6	pubmed	pubmed	PROPN
dti-2638	332	7	https://doi.org/10.1016/s0140-6736(21)02724-0	https://doi.org/10.1016/s0140-6736(21)02724-0	PROPN
dti-2638	332	8	https://www.ncbi.nlm.nih.gov/pubmed/35065702	https://www.ncbi.nlm.nih.gov/pubmed/35065702	NUM
dti-2638	332	9	https://doi.org/10.1016/s1473-3099(17)30753-3	https://doi.org/10.1016/s1473-3099(17)30753-3	NOUN
dti-2638	332	10	https://www.ncbi.nlm.nih.gov/pubmed/29276051	https://www.ncbi.nlm.nih.gov/pubmed/29276051	NUM
dti-2638	332	11	https://doi.org/10.1016/j.bcp.2005.12.016	https://doi.org/10.1016/j.bcp.2005.12.016	PROPN
dti-2638	332	12	https://www.ncbi.nlm.nih.gov/pubmed/16412984	https://www.ncbi.nlm.nih.gov/pubmed/16412984	PROPN
dti-2638	332	13	https://doi.org/10.1038/nrd2201	https://doi.org/10.1038/nrd2201	VERB
dti-2638	332	14	https://www.ncbi.nlm.nih.gov/pubmed/17159923	https://www.ncbi.nlm.nih.gov/pubmed/17159923	NUM
dti-2638	332	15	https://doi.org/10.1002/biof.5520270110	https://doi.org/10.1002/biof.5520270110	PROPN
dti-2638	332	16	https://www.ncbi.nlm.nih.gov/pubmed/17012768	https://www.ncbi.nlm.nih.gov/pubmed/17012768	PRON
dti-2638	332	17	https://doi.org/10.33393/dti.2023.2595	https://doi.org/10.33393/dti.2023.2595	NOUN
dti-2638	332	18	https://www.ncbi.nlm.nih.gov/pubmed/37275512	https://www.ncbi.nlm.nih.gov/pubmed/37275512	X
dti-2638	332	19	https://doi.org/10.1128/msystems.00194-20	https://doi.org/10.1128/msystems.00194-20	NOUN
dti-2638	332	20	https://www.ncbi.nlm.nih.gov/pubmed/32457239	https://www.ncbi.nlm.nih.gov/pubmed/32457239	NUM
dti-2638	332	21	https://doi.org/10.2174/1871526522666220321153332	https://doi.org/10.2174/1871526522666220321153332	X
dti-2638	332	22	https://www.ncbi.nlm.nih.gov/pubmed/35319398	https://www.ncbi.nlm.nih.gov/pubmed/35319398	X
dti-2638	332	23	https://doi.org/10.1016/j.vetmic.2015.03.024	https://doi.org/10.1016/j.vetmic.2015.03.024	VERB
dti-2638	332	24	https://www.ncbi.nlm.nih.gov/pubmed/25888312	https://www.ncbi.nlm.nih.gov/pubmed/25888312	PROPN
dti-2638	332	25	https://doi.org/10.3390/ijms22042050	https://doi.org/10.3390/ijms22042050	PROPN
dti-2638	332	26	https://www.ncbi.nlm.nih.gov/pubmed/33669570	https://www.ncbi.nlm.nih.gov/pubmed/33669570	NUM
dti-2638	332	27	https://doi.org/10.3762/bjoc.14.23	https://doi.org/10.3762/bjoc.14.23	PROPN
dti-2638	332	28	https://www.ncbi.nlm.nih.gov/pubmed/29507640	https://www.ncbi.nlm.nih.gov/pubmed/29507640	PROPN
dti-2638	332	29	https://doi.org/10.1007/7355_2017_17	https://doi.org/10.1007/7355_2017_17	PROPN
dti-2638	332	30	https://doi.org/10.3389/fmicb.2023.1201495	https://doi.org/10.3389/fmicb.2023.1201495	PROPN
dti-2638	332	31	https://www.ncbi.nlm.nih.gov/pubmed/37180278	https://www.ncbi.nlm.nih.gov/pubmed/37180278	NUM
dti-2638	333	1	https://doi.org/10.3390/antibiotics9110779	https://doi.org/10.3390/antibiotics9110779	PROPN
dti-2638	333	2	https://www.ncbi.nlm.nih.gov/pubmed/33171916	https://www.ncbi.nlm.nih.gov/pubmed/33171916	NUM
dti-2638	333	3	https://doi.org/10.2174/1872208310666160728104450	https://doi.org/10.2174/1872208310666160728104450	NOUN
dti-2638	333	4	https://www.ncbi.nlm.nih.gov/pubmed/27468815	https://www.ncbi.nlm.nih.gov/pubmed/27468815	X
dti-2638	333	5	https://doi.org/10.2174/1386207323666200425205808	https://doi.org/10.2174/1386207323666200425205808	NOUN
dti-2638	333	6	https://www.ncbi.nlm.nih.gov/pubmed/32334498	https://www.ncbi.nlm.nih.gov/pubmed/32334498	NUM
dti-2638	333	7	https://doi.org/10.1128/mbio.02331-17	https://doi.org/10.1128/mbio.02331-17	NOUN
dti-2638	333	8	https://www.ncbi.nlm.nih.gov/pubmed/29789364	https://www.ncbi.nlm.nih.gov/pubmed/29789364	NUM
dti-2638	333	9	https://doi.org/10.1016/b978-0-12-814905-8.00001-0	https://doi.org/10.1016/b978-0-12-814905-8.00001-0	PROPN
dti-2638	333	10	https://doi.org/10.3389/fmolb.2023.1203672	https://doi.org/10.3389/fmolb.2023.1203672	PROPN
dti-2638	333	11	https://pubmed.ncbi.nlm.nih.gov/37635941/	https://pubmed.ncbi.nlm.nih.gov/37635941/	PROPN
dti-2638	333	12	https://doi.org/10.1073/pnas.1819796116	https://doi.org/10.1073/pnas.1819796116	ADV
dti-2638	333	13	https://www.ncbi.nlm.nih.gov/pubmed/30850547	https://www.ncbi.nlm.nih.gov/pubmed/30850547	NUM
dti-2638	333	14	https://doi.org/10.1073/pnas.0407229101	https://doi.org/10.1073/pnas.0407229101	NOUN
dti-2638	333	15	https://www.ncbi.nlm.nih.gov/pubmed/15505212	https://www.ncbi.nlm.nih.gov/pubmed/15505212	NUM
dti-2638	333	16	https://doi.org/10.1128/microbiolspec.vmbf-0018-2015	https://doi.org/10.1128/microbiolspec.vmbf-0018-2015	PROPN
dti-2638	333	17	https://www.ncbi.nlm.nih.gov/pubmed/27227296	https://www.ncbi.nlm.nih.gov/pubmed/27227296	PRON
dti-2638	333	18	https://doi.org/10.1016/j.micpath.2018.05.046	https://doi.org/10.1016/j.micpath.2018.05.046	VERB
dti-2638	333	19	https://www.ncbi.nlm.nih.gov/pubmed/29857121	https://www.ncbi.nlm.nih.gov/pubmed/29857121	NUM
dti-2638	333	20	https://doi.org/10.1039/b703021p	https://doi.org/10.1039/b703021p	PROPN
dti-2638	333	21	https://www.ncbi.nlm.nih.gov/pubmed/18568169	https://www.ncbi.nlm.nih.gov/pubmed/18568169	PRON
dti-2638	333	22	https://doi.org/10.3389/fmicb.2021.634593	https://doi.org/10.3389/fmicb.2021.634593	PROPN
dti-2638	333	23	https://www.ncbi.nlm.nih.gov/pubmed/33935995	https://www.ncbi.nlm.nih.gov/pubmed/33935995	CCONJ
dti-2638	333	24	https://doi.org/10.1139/cjm-2014-0666	https://doi.org/10.1139/cjm-2014-0666	VERB
dti-2638	333	25	https://www.ncbi.nlm.nih.gov/pubmed/25388098	https://www.ncbi.nlm.nih.gov/pubmed/25388098	NUM
dti-2638	333	26	https://doi.org/10.1186/s12906-019-2428-5	https://doi.org/10.1186/s12906-019-2428-5	NUM
dti-2638	333	27	https://www.ncbi.nlm.nih.gov/pubmed/30654785	https://www.ncbi.nlm.nih.gov/pubmed/30654785	NUM
dti-2638	334	1	gajera	gajera	NOUN
dti-2638	334	2	et	et	PROPN
dti-2638	334	3	al	al	PROPN
dti-2638	334	4	drug	drug	PROPN
dti-2638	334	5	target	target	NOUN
dti-2638	334	6	insights	insight	NOUN
dti-2638	334	7	2023	2023	NUM
dti-2638	334	8	;	;	PUNCT
dti-2638	334	9	17	17	NUM
dti-2638	334	10	:	:	SYM
dti-2638	334	11	109	109	NUM
dti-2638	334	12	©	©	PROPN
dti-2638	334	13	2023	2023	NUM
dti-2638	334	14	the	the	DET
dti-2638	334	15	authors	author	NOUN
dti-2638	334	16	.	.	PUNCT
dti-2638	335	1	published	publish	VERB
dti-2638	335	2	by	by	ADP
dti-2638	335	3	aboutscience	aboutscience	NOUN
dti-2638	335	4	www.aboutscience.eu	www.aboutscience.eu	PROPN
dti-2638	335	5	28	28	NUM
dti-2638	335	6	.	.	PUNCT
dti-2638	336	1	van	van	PROPN
dti-2638	336	2	alst	alst	PROPN
dti-2638	336	3	ne	ne	PROPN
dti-2638	336	4	,	,	PUNCT
dti-2638	336	5	picardo	picardo	PROPN
dti-2638	336	6	kf	kf	PROPN
dti-2638	336	7	,	,	PUNCT
dti-2638	336	8	iglewski	iglewski	PROPN
dti-2638	336	9	bh	bh	PROPN
dti-2638	336	10	,	,	PUNCT
dti-2638	336	11	haidaris	haidaris	PROPN
dti-2638	336	12	cg	cg	PROPN
dti-2638	336	13	.	.	PUNCT
dti-2638	337	1	nitrate	nitrate	NOUN
dti-2638	337	2	sensing	sensing	NOUN
dti-2638	337	3	and	and	CCONJ
dti-2638	337	4	metabolism	metabolism	NOUN
dti-2638	337	5	modulate	modulate	VERB
dti-2638	337	6	motility	motility	NOUN
dti-2638	337	7	,	,	PUNCT
dti-2638	337	8	biofilm	biofilm	NOUN
dti-2638	337	9	formation	formation	NOUN
dti-2638	337	10	,	,	PUNCT
dti-2638	337	11	and	and	CCONJ
dti-2638	337	12	virulence	virulence	NOUN
dti-2638	337	13	in	in	ADP
dti-2638	337	14	pseudomonas	pseudomona	NOUN
dti-2638	337	15	aeruginosa	aeruginosa	NOUN
dti-2638	337	16	.	.	PUNCT
dti-2638	338	1	infect	infect	VERB
dti-2638	338	2	immun	immun	PROPN
dti-2638	338	3	.	.	PUNCT
dti-2638	339	1	2007;75(8):3780	2007;75(8):3780	NUM
dti-2638	339	2	-	-	SYM
dti-2638	339	3	3790	3790	NUM
dti-2638	339	4	.	.	PUNCT
dti-2638	340	1	crossref	crossref	PROPN
dti-2638	340	2	pubmed	pubmed	PROPN
dti-2638	340	3	29	29	NUM
dti-2638	340	4	.	.	PUNCT
dti-2638	341	1	han	han	PROPN
dti-2638	341	2	s	s	PROPN
dti-2638	341	3	,	,	PUNCT
dti-2638	341	4	liu	liu	PROPN
dti-2638	341	5	j	j	PROPN
dti-2638	341	6	,	,	PUNCT
dti-2638	341	7	li	li	PROPN
dti-2638	341	8	m	m	PROPN
dti-2638	341	9	,	,	PUNCT
dti-2638	341	10	et	et	PROPN
dti-2638	341	11	al	al	PROPN
dti-2638	341	12	.	.	PROPN
dti-2638	342	1	dna	dna	PROPN
dti-2638	342	2	methyltransferase	methyltransferase	NOUN
dti-2638	342	3	regulates	regulate	VERB
dti-2638	342	4	nitric	nitric	ADJ
dti-2638	342	5	oxide	oxide	NOUN
dti-2638	342	6	homeostasis	homeostasis	NOUN
dti-2638	342	7	and	and	CCONJ
dti-2638	342	8	virulence	virulence	NOUN
dti-2638	342	9	in	in	ADP
dti-2638	342	10	a	a	DET
dti-2638	342	11	chronically	chronically	ADV
dti-2638	342	12	adapted	adapt	VERB
dti-2638	342	13	pseudomonas	pseudomona	NOUN
dti-2638	342	14	aeruginosa	aeruginosa	NOUN
dti-2638	342	15	strain	strain	NOUN
dti-2638	342	16	.	.	PUNCT
dti-2638	343	1	msystems	msystem	NOUN
dti-2638	343	2	.	.	PUNCT
dti-2638	344	1	2022;7(5	2022;7(5	X
dti-2638	344	2	):	):	PUNCT
dti-2638	344	3	e0043422	e0043422	NOUN
dti-2638	344	4	.	.	PUNCT
dti-2638	345	1	crossref	crossref	PROPN
dti-2638	345	2	pubmed	pubmed	PROPN
dti-2638	345	3	30	30	PROPN
dti-2638	345	4	.	.	PUNCT
dti-2638	346	1	toyofuku	toyofuku	PROPN
dti-2638	346	2	m	m	PROPN
dti-2638	346	3	,	,	PUNCT
dti-2638	346	4	yoon	yoon	PROPN
dti-2638	346	5	ss	ss	PROPN
dti-2638	346	6	.	.	PROPN
dti-2638	346	7	nitric	nitric	ADJ
dti-2638	346	8	oxide	oxide	NOUN
dti-2638	346	9	,	,	PUNCT
dti-2638	346	10	an	an	DET
dti-2638	346	11	old	old	ADJ
dti-2638	346	12	molecule	molecule	NOUN
dti-2638	346	13	with	with	ADP
dti-2638	346	14	noble	noble	ADJ
dti-2638	346	15	functions	function	NOUN
dti-2638	346	16	in	in	ADP
dti-2638	346	17	pseudomonas	pseudomona	NOUN
dti-2638	346	18	aeruginosa	aeruginosa	NOUN
dti-2638	346	19	biology	biology	NOUN
dti-2638	346	20	.	.	PUNCT
dti-2638	347	1	adv	adv	PROPN
dti-2638	347	2	microb	microb	PROPN
dti-2638	347	3	physiol	physiol	PROPN
dti-2638	347	4	.	.	PUNCT
dti-2638	348	1	2018;72:117	2018;72:117	NUM
dti-2638	348	2	-	-	SYM
dti-2638	348	3	145	145	NUM
dti-2638	348	4	.	.	PUNCT
dti-2638	349	1	crossref	crossref	PROPN
dti-2638	349	2	pubmed	pubmed	PROPN
dti-2638	349	3	31	31	NUM
dti-2638	349	4	.	.	PUNCT
dti-2638	350	1	barraud	barraud	PROPN
dti-2638	350	2	n	n	CCONJ
dti-2638	350	3	,	,	PUNCT
dti-2638	350	4	kelso	kelso	PROPN
dti-2638	350	5	mj	mj	PROPN
dti-2638	350	6	,	,	PUNCT
dti-2638	350	7	rice	rice	PROPN
dti-2638	350	8	sa	sa	PROPN
dti-2638	350	9	,	,	PUNCT
dti-2638	350	10	kjelleberg	kjelleberg	PROPN
dti-2638	350	11	s.	s.	PROPN
dti-2638	350	12	nitric	nitric	ADJ
dti-2638	350	13	oxide	oxide	NOUN
dti-2638	350	14	:	:	PUNCT
dti-2638	350	15	a	a	DET
dti-2638	350	16	key	key	ADJ
dti-2638	350	17	mediator	mediator	NOUN
dti-2638	350	18	of	of	ADP
dti-2638	350	19	biofilm	biofilm	NOUN
dti-2638	350	20	dispersal	dispersal	NOUN
dti-2638	350	21	with	with	ADP
dti-2638	350	22	applications	application	NOUN
dti-2638	350	23	in	in	ADP
dti-2638	350	24	infectious	infectious	ADJ
dti-2638	350	25	diseases	disease	NOUN
dti-2638	350	26	.	.	PUNCT
dti-2638	351	1	curr	curr	PROPN
dti-2638	351	2	pharm	pharm	PROPN
dti-2638	351	3	des	des	PROPN
dti-2638	351	4	.	.	PROPN
dti-2638	351	5	2015;21(1):31	2015;21(1):31	NUM
dti-2638	351	6	-	-	SYM
dti-2638	351	7	42	42	NUM
dti-2638	351	8	.	.	PUNCT
dti-2638	352	1	crossref	crossref	PROPN
dti-2638	352	2	pubmed	pubmed	PROPN
dti-2638	352	3	32	32	NUM
dti-2638	352	4	.	.	PUNCT
dti-2638	353	1	carvalho	carvalho	PROPN
dti-2638	353	2	sm	sm	PROPN
dti-2638	353	3	,	,	PUNCT
dti-2638	353	4	beas	beas	PROPN
dti-2638	353	5	jz	jz	PROPN
dti-2638	353	6	,	,	PUNCT
dti-2638	353	7	videira	videira	PROPN
dti-2638	353	8	mam	mam	PROPN
dti-2638	353	9	,	,	PUNCT
dti-2638	353	10	saraiva	saraiva	NOUN
dti-2638	353	11	lm	lm	PROPN
dti-2638	353	12	.	.	PUNCT
dti-2638	354	1	defenses	defense	NOUN
dti-2638	354	2	of	of	ADP
dti-2638	354	3	multidrug	multidrug	NOUN
dti-2638	354	4	resistant	resistant	ADJ
dti-2638	354	5	pathogens	pathogen	NOUN
dti-2638	354	6	against	against	ADP
dti-2638	354	7	reactive	reactive	ADJ
dti-2638	354	8	nitrogen	nitrogen	NOUN
dti-2638	354	9	species	specie	NOUN
dti-2638	354	10	produced	produce	VERB
dti-2638	354	11	in	in	ADP
dti-2638	354	12	infected	infected	ADJ
dti-2638	354	13	hosts	host	NOUN
dti-2638	354	14	.	.	PUNCT
dti-2638	355	1	adv	adv	PROPN
dti-2638	355	2	microb	microb	PROPN
dti-2638	355	3	physiol	physiol	PROPN
dti-2638	355	4	.	.	PUNCT
dti-2638	356	1	2022;80:85155	2022;80:85155	X
dti-2638	356	2	.	.	X
dti-2638	356	3	crossref	crossref	PROPN
dti-2638	356	4	pubmed	pubmed	PROPN
dti-2638	356	5	33	33	NUM
dti-2638	356	6	.	.	PUNCT
dti-2638	357	1	wang	wang	PROPN
dti-2638	357	2	z	z	PROPN
dti-2638	357	3	,	,	PUNCT
dti-2638	357	4	xie	xie	PROPN
dti-2638	357	5	x	x	PROPN
dti-2638	357	6	,	,	PUNCT
dti-2638	357	7	shang	shang	PROPN
dti-2638	357	8	d	d	PROPN
dti-2638	357	9	,	,	PUNCT
dti-2638	357	10	et	et	PROPN
dti-2638	357	11	al	al	PROPN
dti-2638	357	12	.	.	PUNCT
dti-2638	358	1	a	a	DET
dti-2638	358	2	c	c	NOUN
dti-2638	358	3	-	-	PUNCT
dti-2638	358	4	di	di	NOUN
dti-2638	358	5	-	-	PUNCT
dti-2638	358	6	gmp	gmp	NOUN
dti-2638	358	7	signaling	signal	VERB
dti-2638	358	8	cascade	cascade	NOUN
dti-2638	358	9	controls	control	NOUN
dti-2638	358	10	motility	motility	NOUN
dti-2638	358	11	,	,	PUNCT
dti-2638	358	12	biofilm	biofilm	NOUN
dti-2638	358	13	formation	formation	NOUN
dti-2638	358	14	,	,	PUNCT
dti-2638	358	15	and	and	CCONJ
dti-2638	358	16	virulence	virulence	NOUN
dti-2638	358	17	in	in	ADP
dti-2638	358	18	burkholderia	burkholderia	PROPN
dti-2638	358	19	thailandensis	thailandensis	PROPN
dti-2638	358	20	.	.	PUNCT
dti-2638	359	1	appl	appl	PROPN
dti-2638	359	2	environ	environ	X
dti-2638	359	3	microbiol	microbiol	PROPN
dti-2638	359	4	.	.	PUNCT
dti-2638	360	1	2022;88(7):e0252921	2022;88(7):e0252921	X
dti-2638	360	2	.	.	PUNCT
dti-2638	360	3	crossref	crossref	PROPN
dti-2638	360	4	pubmed	pubmed	PROPN
dti-2638	360	5	34	34	NUM
dti-2638	360	6	.	.	PUNCT
dti-2638	361	1	kakishima	kakishima	PROPN
dti-2638	361	2	k	k	PROPN
dti-2638	361	3	,	,	PUNCT
dti-2638	361	4	shiratsuchi	shiratsuchi	VERB
dti-2638	361	5	a	a	PRON
dti-2638	361	6	,	,	PUNCT
dti-2638	361	7	taoka	taoka	NOUN
dti-2638	361	8	a	a	X
dti-2638	361	9	,	,	PUNCT
dti-2638	361	10	nakanishi	nakanishi	PROPN
dti-2638	361	11	y	y	PROPN
dti-2638	361	12	,	,	PUNCT
dti-2638	361	13	fukumori	fukumori	PROPN
dti-2638	361	14	y.	y.	NOUN
dti-2638	361	15	participation	participation	NOUN
dti-2638	361	16	of	of	ADP
dti-2638	361	17	nitric	nitric	ADJ
dti-2638	361	18	oxide	oxide	NOUN
dti-2638	361	19	reductase	reductase	NOUN
dti-2638	361	20	in	in	ADP
dti-2638	361	21	survival	survival	NOUN
dti-2638	361	22	of	of	ADP
dti-2638	361	23	pseudomonas	pseudomona	NOUN
dti-2638	361	24	aeruginosa	aeruginosa	NOUN
dti-2638	361	25	in	in	ADP
dti-2638	361	26	lps	lps	PROPN
dti-2638	361	27	-	-	PUNCT
dti-2638	361	28	activated	activate	VERB
dti-2638	361	29	macrophages	macrophage	NOUN
dti-2638	361	30	.	.	PUNCT
dti-2638	362	1	biochem	biochem	PROPN
dti-2638	362	2	biophys	biophy	VERB
dti-2638	362	3	res	re	NOUN
dti-2638	362	4	commun	commun	PROPN
dti-2638	362	5	.	.	PUNCT
dti-2638	363	1	2007;355(2):587	2007;355(2):587	PROPN
dti-2638	363	2	-	-	SYM
dti-2638	363	3	591	591	NUM
dti-2638	363	4	.	.	PUNCT
dti-2638	364	1	crossref	crossref	PROPN
dti-2638	364	2	pubmed	pubmed	PROPN
dti-2638	364	3	35	35	PROPN
dti-2638	364	4	.	.	PUNCT
dti-2638	365	1	abelyan	abelyan	PROPN
dti-2638	365	2	n	n	CCONJ
dti-2638	365	3	,	,	PUNCT
dti-2638	365	4	grabski	grabski	ADP
dti-2638	365	5	h	h	NOUN
dti-2638	365	6	,	,	PUNCT
dti-2638	365	7	tiratsuyan	tiratsuyan	PROPN
dti-2638	365	8	s.	s.	PROPN
dti-2638	365	9	in	in	ADP
dti-2638	365	10	silico	silico	NOUN
dti-2638	365	11	screening	screen	VERB
dti-2638	365	12	of	of	ADP
dti-2638	365	13	flavones	flavone	NOUN
dti-2638	365	14	and	and	CCONJ
dti-2638	365	15	its	its	PRON
dti-2638	365	16	derivatives	derivative	NOUN
dti-2638	365	17	as	as	ADP
dti-2638	365	18	potential	potential	ADJ
dti-2638	365	19	inhibitors	inhibitor	NOUN
dti-2638	365	20	of	of	ADP
dti-2638	365	21	quorumsensing	quorumsense	VERB
dti-2638	365	22	regulator	regulator	NOUN
dti-2638	365	23	lasr	lasr	PROPN
dti-2638	365	24	of	of	ADP
dti-2638	365	25	pseudomonas	pseudomona	NOUN
dti-2638	365	26	aeruginosa	aeruginosa	NOUN
dti-2638	365	27	.	.	PUNCT
dti-2638	366	1	mol	mol	ADP
dti-2638	366	2	biol	biol	PROPN
dti-2638	366	3	(	(	PUNCT
dti-2638	366	4	mosk	mosk	PROPN
dti-2638	366	5	)	)	PUNCT
dti-2638	366	6	.	.	PUNCT
dti-2638	367	1	2020;54(1):153	2020;54(1):153	NUM
dti-2638	367	2	-	-	SYM
dti-2638	367	3	163	163	NUM
dti-2638	367	4	.	.	PUNCT
dti-2638	368	1	crossref	crossref	PROPN
dti-2638	368	2	pubmed	pubmed	PROPN
dti-2638	368	3	36	36	NUM
dti-2638	368	4	.	.	PUNCT
dti-2638	369	1	narayanaswamy	narayanaswamy	PROPN
dti-2638	369	2	r	r	PROPN
dti-2638	369	3	,	,	PUNCT
dti-2638	369	4	prabhakaran	prabhakaran	PROPN
dti-2638	369	5	vs	vs	ADP
dti-2638	369	6	,	,	PUNCT
dti-2638	369	7	al	al	PROPN
dti-2638	369	8	-	-	PUNCT
dti-2638	369	9	ansari	ansari	PROPN
dti-2638	369	10	mm	mm	PROPN
dti-2638	369	11	,	,	PUNCT
dti-2638	369	12	al	al	PROPN
dti-2638	369	13	-	-	PUNCT
dti-2638	369	14	humaid	humaid	PROPN
dti-2638	369	15	la	la	PROPN
dti-2638	369	16	,	,	PUNCT
dti-2638	369	17	tiwari	tiwari	ADJ
dti-2638	370	1	p.	p.	NOUN
dti-2638	370	2	an	an	PRON
dti-2638	370	3	in	in	ADP
dti-2638	370	4	silico	silico	NOUN
dti-2638	370	5	analysis	analysis	NOUN
dti-2638	370	6	of	of	ADP
dti-2638	370	7	synthetic	synthetic	ADJ
dti-2638	370	8	and	and	CCONJ
dti-2638	370	9	natural	natural	ADJ
dti-2638	370	10	compounds	compound	NOUN
dti-2638	370	11	as	as	ADP
dti-2638	370	12	inhibitors	inhibitor	NOUN
dti-2638	370	13	of	of	ADP
dti-2638	370	14	nitrous	nitrous	ADJ
dti-2638	370	15	oxide	oxide	NOUN
dti-2638	370	16	reductase	reductase	NOUN
dti-2638	370	17	(	(	PUNCT
dti-2638	370	18	n2or	n2or	NUM
dti-2638	370	19	)	)	PUNCT
dti-2638	370	20	and	and	CCONJ
dti-2638	370	21	nitrite	nitrite	NOUN
dti-2638	370	22	reductase	reductase	NOUN
dti-2638	370	23	(	(	PUNCT
dti-2638	370	24	nir	nir	NOUN
dti-2638	370	25	)	)	PUNCT
dti-2638	370	26	.	.	PUNCT
dti-2638	371	1	toxics	toxic	NOUN
dti-2638	371	2	.	.	PUNCT
dti-2638	372	1	2023;11(8):660	2023;11(8):660	PROPN
dti-2638	372	2	.	.	PUNCT
dti-2638	373	1	crossref	crossref	PROPN
dti-2638	373	2	pubmed	pubmed	PROPN
dti-2638	373	3	37	37	NUM
dti-2638	373	4	.	.	PUNCT
dti-2638	374	1	wallach	wallach	PROPN
dti-2638	374	2	i	i	PRON
dti-2638	374	3	,	,	PUNCT
dti-2638	374	4	dzamba	dzamba	NOUN
dti-2638	374	5	m	m	PROPN
dti-2638	374	6	,	,	PUNCT
dti-2638	374	7	heifets	heifet	NOUN
dti-2638	374	8	a.	a.	NOUN
dti-2638	374	9	atomnet	atomnet	PROPN
dti-2638	374	10	:	:	PUNCT
dti-2638	374	11	a	a	DET
dti-2638	374	12	deep	deep	ADJ
dti-2638	374	13	convolutional	convolutional	ADJ
dti-2638	374	14	neural	neural	ADJ
dti-2638	374	15	network	network	NOUN
dti-2638	374	16	for	for	ADP
dti-2638	374	17	bioactivity	bioactivity	NOUN
dti-2638	374	18	prediction	prediction	NOUN
dti-2638	374	19	in	in	ADP
dti-2638	374	20	structurebased	structurebase	VERB
dti-2638	374	21	drug	drug	NOUN
dti-2638	374	22	discovery	discovery	NOUN
dti-2638	374	23	.	.	PUNCT
dti-2638	375	1	arxiv	arxiv	PROPN
dti-2638	375	2	preprint	preprint	PROPN
dti-2638	375	3	arxiv:1510.02855	arxiv:1510.02855	PROPN
dti-2638	375	4	.	.	PUNCT
dti-2638	376	1	2015	2015	NUM
dti-2638	376	2	.	.	PUNCT
dti-2638	377	1	crossref	crossref	PROPN
dti-2638	377	2	38	38	NUM
dti-2638	377	3	.	.	PUNCT
dti-2638	378	1	patel	patel	PROPN
dti-2638	378	2	p	p	PROPN
dti-2638	378	3	,	,	PUNCT
dti-2638	378	4	joshi	joshi	PROPN
dti-2638	378	5	c	c	PROPN
dti-2638	378	6	,	,	PUNCT
dti-2638	378	7	kothari	kothari	PROPN
dti-2638	378	8	v.	v.	ADP
dti-2638	378	9	antipathogenic	antipathogenic	ADJ
dti-2638	378	10	potential	potential	NOUN
dti-2638	378	11	of	of	ADP
dti-2638	378	12	a	a	DET
dti-2638	378	13	polyherbal	polyherbal	ADJ
dti-2638	378	14	wound	wound	NOUN
dti-2638	378	15	-	-	PUNCT
dti-2638	378	16	care	care	NOUN
dti-2638	378	17	formulation	formulation	NOUN
dti-2638	378	18	(	(	PUNCT
dti-2638	378	19	herboheal	herboheal	NOUN
dti-2638	378	20	)	)	PUNCT
dti-2638	378	21	against	against	ADP
dti-2638	378	22	certain	certain	ADJ
dti-2638	378	23	wound	wound	NOUN
dti-2638	378	24	-	-	PUNCT
dti-2638	378	25	infective	infective	ADJ
dti-2638	378	26	gram	gram	NOUN
dti-2638	378	27	-	-	PUNCT
dti-2638	378	28	negative	negative	ADJ
dti-2638	378	29	bacteria	bacteria	NOUN
dti-2638	378	30	.	.	PUNCT
dti-2638	379	1	adv	adv	PROPN
dti-2638	379	2	pharmacol	pharmacol	PROPN
dti-2638	379	3	sci	sci	PROPN
dti-2638	379	4	.	.	PUNCT
dti-2638	379	5	2019;2019:1739868	2019;2019:1739868	NUM
dti-2638	379	6	.	.	PUNCT
dti-2638	380	1	crossref	crossref	PROPN
dti-2638	380	2	pubmed	pubmed	PROPN
dti-2638	380	3	39	39	NUM
dti-2638	380	4	.	.	PUNCT
dti-2638	381	1	abd	abd	PROPN
dti-2638	381	2	el	el	PROPN
dti-2638	381	3	-	-	PUNCT
dti-2638	381	4	aleam	aleam	PROPN
dti-2638	381	5	rh	rh	PROPN
dti-2638	381	6	,	,	PUNCT
dti-2638	381	7	sayed	say	VERB
dti-2638	381	8	am	am	PROPN
dti-2638	381	9	,	,	PUNCT
dti-2638	381	10	taha	taha	PROPN
dti-2638	381	11	mn	mn	PROPN
dti-2638	381	12	,	,	PUNCT
dti-2638	381	13	george	george	PROPN
dti-2638	381	14	rf	rf	PROPN
dti-2638	381	15	,	,	PUNCT
dti-2638	381	16	georgey	georgey	PROPN
dti-2638	381	17	hh	hh	PROPN
dti-2638	381	18	,	,	PUNCT
dti-2638	382	1	abdel	abdel	PROPN
dti-2638	382	2	-	-	PUNCT
dti-2638	382	3	rahman	rahman	PROPN
dti-2638	382	4	hm	hm	PROPN
dti-2638	382	5	.	.	PUNCT
dti-2638	382	6	design	design	NOUN
dti-2638	382	7	and	and	CCONJ
dti-2638	382	8	synthesis	synthesis	NOUN
dti-2638	382	9	of	of	ADP
dti-2638	382	10	novel	novel	ADJ
dti-2638	382	11	benzimidazole	benzimidazole	NOUN
dti-2638	382	12	derivatives	derivative	NOUN
dti-2638	382	13	as	as	ADP
dti-2638	382	14	potential	potential	ADJ
dti-2638	382	15	pseudomonas	pseudomona	NOUN
dti-2638	382	16	aeruginosa	aeruginosa	NOUN
dti-2638	382	17	antibiofilm	antibiofilm	NOUN
dti-2638	382	18	agents	agent	NOUN
dti-2638	382	19	inhibiting	inhibit	VERB
dti-2638	382	20	lasr	lasr	PROPN
dti-2638	382	21	:	:	PUNCT
dti-2638	382	22	evidence	evidence	NOUN
dti-2638	382	23	from	from	ADP
dti-2638	382	24	comprehensive	comprehensive	ADJ
dti-2638	382	25	molecular	molecular	ADJ
dti-2638	382	26	dynamics	dynamic	NOUN
dti-2638	382	27	simulation	simulation	NOUN
dti-2638	382	28	and	and	CCONJ
dti-2638	382	29	in	in	ADP
dti-2638	382	30	vitro	vitro	X
dti-2638	382	31	investigation	investigation	NOUN
dti-2638	382	32	.	.	PUNCT
dti-2638	383	1	eur	eur	PROPN
dti-2638	383	2	j	j	PROPN
dti-2638	383	3	med	med	PROPN
dti-2638	383	4	chem	chem	NOUN
dti-2638	383	5	.	.	PUNCT
dti-2638	384	1	2022;241:114629	2022;241:114629	NUM
dti-2638	384	2	.	.	PUNCT
dti-2638	385	1	crossref	crossref	PROPN
dti-2638	385	2	pubmed	pubmed	PROPN
dti-2638	385	3	40	40	NUM
dti-2638	385	4	.	.	PUNCT
dti-2638	386	1	hernando	hernando	NOUN
dti-2638	386	2	-	-	PUNCT
dti-2638	386	3	amado	amado	NOUN
dti-2638	386	4	s	s	NOUN
dti-2638	386	5	,	,	PUNCT
dti-2638	386	6	alcalde	alcalde	NOUN
dti-2638	386	7	-	-	PUNCT
dti-2638	386	8	rico	rico	PROPN
dti-2638	386	9	m	m	PROPN
dti-2638	386	10	,	,	PUNCT
dti-2638	386	11	gil	gil	PROPN
dti-2638	386	12	-	-	PUNCT
dti-2638	386	13	gil	gil	PROPN
dti-2638	386	14	t	t	PROPN
dti-2638	386	15	,	,	PUNCT
dti-2638	386	16	valverde	valverde	PROPN
dti-2638	386	17	jr	jr	PROPN
dti-2638	386	18	,	,	PUNCT
dti-2638	386	19	martínez	martínez	PROPN
dti-2638	386	20	jl	jl	PROPN
dti-2638	386	21	.	.	PUNCT
dti-2638	387	1	naringenin	naringenin	PROPN
dti-2638	387	2	inhibition	inhibition	NOUN
dti-2638	387	3	of	of	ADP
dti-2638	387	4	the	the	DET
dti-2638	387	5	pseudomonas	pseudomona	NOUN
dti-2638	387	6	aeruginosa	aeruginosa	NOUN
dti-2638	387	7	quorum	quorum	NOUN
dti-2638	387	8	sensing	sense	VERB
dti-2638	387	9	response	response	NOUN
dti-2638	387	10	is	be	AUX
dti-2638	387	11	based	base	VERB
dti-2638	387	12	on	on	ADP
dti-2638	387	13	its	its	PRON
dti-2638	387	14	time	time	NOUN
dti-2638	387	15	-	-	PUNCT
dti-2638	387	16	dependent	dependent	ADJ
dti-2638	387	17	competition	competition	NOUN
dti-2638	387	18	with	with	ADP
dti-2638	387	19	n-(3	n-(3	NOUN
dti-2638	387	20	-	-	PUNCT
dti-2638	387	21	oxo	oxo	NOUN
dti-2638	387	22	-	-	PUNCT
dti-2638	387	23	dodecanoyl)-l	dodecanoyl)-l	NOUN
dti-2638	387	24	-	-	PUNCT
dti-2638	387	25	homoserine	homoserine	NOUN
dti-2638	387	26	lactone	lactone	NOUN
dti-2638	387	27	for	for	ADP
dti-2638	387	28	lasr	lasr	PROPN
dti-2638	387	29	binding	binding	NOUN
dti-2638	387	30	.	.	PUNCT
dti-2638	388	1	front	front	NOUN
dti-2638	388	2	mol	mol	ADP
dti-2638	388	3	biosci	biosci	PROPN
dti-2638	388	4	.	.	PUNCT
dti-2638	389	1	2020;7:25	2020;7:25	PROPN
dti-2638	389	2	.	.	PUNCT
dti-2638	390	1	crossref	crossref	PROPN
dti-2638	390	2	pubmed	pubmed	PROPN
dti-2638	390	3	41	41	NUM
dti-2638	390	4	.	.	PUNCT
dti-2638	391	1	o’brien	o’brien	PROPN
dti-2638	391	2	kt	kt	PROPN
dti-2638	391	3	,	,	PUNCT
dti-2638	391	4	noto	noto	PROPN
dti-2638	391	5	jg	jg	PROPN
dti-2638	391	6	,	,	PUNCT
dti-2638	391	7	nichols	nichols	PROPN
dti-2638	391	8	-	-	PUNCT
dti-2638	391	9	o’neill	o’neill	PROPN
dti-2638	391	10	l	l	NOUN
dti-2638	391	11	,	,	PUNCT
dti-2638	391	12	perez	perez	PROPN
dti-2638	391	13	lj	lj	PROPN
dti-2638	391	14	.	.	PUNCT
dti-2638	391	15	potent	potent	ADJ
dti-2638	391	16	irreversible	irreversible	ADJ
dti-2638	391	17	inhibitors	inhibitor	NOUN
dti-2638	391	18	of	of	ADP
dti-2638	391	19	lasr	lasr	PROPN
dti-2638	391	20	quorum	quorum	PROPN
dti-2638	391	21	sensing	sense	VERB
dti-2638	391	22	in	in	ADP
dti-2638	391	23	pseudomonas	pseudomona	NOUN
dti-2638	391	24	aeruginosa	aeruginosa	NOUN
dti-2638	391	25	.	.	PUNCT
dti-2638	392	1	acs	acs	PROPN
dti-2638	392	2	med	med	PROPN
dti-2638	392	3	chem	chem	PROPN
dti-2638	392	4	lett	lett	PROPN
dti-2638	392	5	.	.	PUNCT
dti-2638	393	1	2015;6(2):162	2015;6(2):162	X
dti-2638	393	2	-	-	SYM
dti-2638	393	3	167	167	NUM
dti-2638	393	4	.	.	PUNCT
dti-2638	394	1	crossref	crossref	PROPN
dti-2638	394	2	pubmed	pubmed	PROPN
dti-2638	394	3	42	42	NUM
dti-2638	394	4	.	.	PUNCT
dti-2638	395	1	walsh	walsh	PROPN
dti-2638	395	2	c.	c.	PROPN
dti-2638	395	3	where	where	SCONJ
dti-2638	395	4	will	will	AUX
dti-2638	395	5	new	new	ADJ
dti-2638	395	6	antibiotics	antibiotic	NOUN
dti-2638	395	7	come	come	VERB
dti-2638	395	8	from	from	ADP
dti-2638	395	9	?	?	PUNCT
dti-2638	396	1	nat	nat	PROPN
dti-2638	396	2	rev	rev	PROPN
dti-2638	396	3	microbiol	microbiol	PROPN
dti-2638	396	4	.	.	PUNCT
dti-2638	397	1	2003;1(1):65	2003;1(1):65	NUM
dti-2638	397	2	-	-	SYM
dti-2638	397	3	70	70	NUM
dti-2638	397	4	.	.	PUNCT
dti-2638	398	1	crossref	crossref	PROPN
dti-2638	398	2	pubmed	pubmed	PROPN
dti-2638	398	3	43	43	NUM
dti-2638	398	4	.	.	PUNCT
dti-2638	399	1	allen	allen	PROPN
dti-2638	399	2	rc	rc	PROPN
dti-2638	399	3	,	,	PUNCT
dti-2638	399	4	popat	popat	NOUN
dti-2638	399	5	r	r	PROPN
dti-2638	399	6	,	,	PUNCT
dti-2638	399	7	diggle	diggle	PROPN
dti-2638	399	8	sp	sp	PROPN
dti-2638	399	9	,	,	PUNCT
dti-2638	399	10	brown	brown	ADJ
dti-2638	399	11	sp	sp	NOUN
dti-2638	399	12	.	.	NOUN
dti-2638	399	13	targeting	target	VERB
dti-2638	399	14	virulence	virulence	NOUN
dti-2638	399	15	:	:	PUNCT
dti-2638	399	16	can	can	AUX
dti-2638	399	17	we	we	PRON
dti-2638	399	18	make	make	VERB
dti-2638	399	19	evolution	evolution	NOUN
dti-2638	399	20	-	-	PUNCT
dti-2638	399	21	proof	proof	ADJ
dti-2638	399	22	drugs	drug	NOUN
dti-2638	399	23	?	?	PUNCT
dti-2638	400	1	nat	nat	PROPN
dti-2638	400	2	rev	rev	PROPN
dti-2638	400	3	microbiol	microbiol	PROPN
dti-2638	400	4	.	.	PUNCT
dti-2638	401	1	2014;12(4):300	2014;12(4):300	NUM
dti-2638	401	2	-	-	SYM
dti-2638	401	3	308	308	NUM
dti-2638	401	4	.	.	PUNCT
dti-2638	402	1	crossref	crossref	PROPN
dti-2638	402	2	pubmed	pubmed	PROPN
dti-2638	402	3	https://doi.org/10.1128/iai.00201-07	https://doi.org/10.1128/iai.00201-07	PROPN
dti-2638	402	4	https://www.ncbi.nlm.nih.gov/pubmed/17526746	https://www.ncbi.nlm.nih.gov/pubmed/17526746	PROPN
dti-2638	402	5	https://doi.org/10.1128/msystems.00434-22	https://doi.org/10.1128/msystems.00434-22	PROPN
dti-2638	402	6	https://www.ncbi.nlm.nih.gov/pubmed/36106744	https://www.ncbi.nlm.nih.gov/pubmed/36106744	PRON
dti-2638	402	7	https://doi.org/10.1016/bs.ampbs.2018.01.005	https://doi.org/10.1016/bs.ampbs.2018.01.005	X
dti-2638	402	8	https://www.ncbi.nlm.nih.gov/pubmed/29778213	https://www.ncbi.nlm.nih.gov/pubmed/29778213	NOUN
dti-2638	402	9	https://doi.org/10.2174/1381612820666140905112822	https://doi.org/10.2174/1381612820666140905112822	ADV
dti-2638	402	10	https://www.ncbi.nlm.nih.gov/pubmed/25189865	https://www.ncbi.nlm.nih.gov/pubmed/25189865	NUM
dti-2638	402	11	https://doi.org/10.1016/bs.ampbs.2022.02.001	https://doi.org/10.1016/bs.ampbs.2022.02.001	X
dti-2638	402	12	https://www.ncbi.nlm.nih.gov/pubmed/35489794	https://www.ncbi.nlm.nih.gov/pubmed/35489794	PRON
dti-2638	402	13	https://doi.org/10.1128/aem.02529-21	https://doi.org/10.1128/aem.02529-21	PROPN
dti-2638	402	14	https://www.ncbi.nlm.nih.gov/pubmed/35323023	https://www.ncbi.nlm.nih.gov/pubmed/35323023	NUM
dti-2638	402	15	https://doi.org/10.1016/j.bbrc.2007.02.017	https://doi.org/10.1016/j.bbrc.2007.02.017	NUM
dti-2638	402	16	https://www.ncbi.nlm.nih.gov/pubmed/17307144	https://www.ncbi.nlm.nih.gov/pubmed/17307144	NUM
dti-2638	402	17	https://doi.org/10.1134/s0026893320010021	https://doi.org/10.1134/s0026893320010021	PROPN
dti-2638	402	18	https://www.ncbi.nlm.nih.gov/pubmed/32163399	https://www.ncbi.nlm.nih.gov/pubmed/32163399	PRON
dti-2638	402	19	https://doi.org/10.3390/toxics11080660	https://doi.org/10.3390/toxics11080660	NOUN
dti-2638	402	20	https://www.ncbi.nlm.nih.gov/pubmed/37624165	https://www.ncbi.nlm.nih.gov/pubmed/37624165	PROPN
dti-2638	402	21	https://doi.org/10.48550/arxiv.1510.02855	https://doi.org/10.48550/arxiv.1510.02855	PROPN
dti-2638	402	22	https://doi.org/10.1155/2019/1739868	https://doi.org/10.1155/2019/1739868	NOUN
dti-2638	402	23	https://www.ncbi.nlm.nih.gov/pubmed/30833966	https://www.ncbi.nlm.nih.gov/pubmed/30833966	PROPN
dti-2638	402	24	https://doi.org/10.1016/j.ejmech.2022.114629	https://doi.org/10.1016/j.ejmech.2022.114629	PROPN
dti-2638	402	25	https://www.ncbi.nlm.nih.gov/pubmed/35961070	https://www.ncbi.nlm.nih.gov/pubmed/35961070	NUM
dti-2638	402	26	https://doi.org/10.3389/fmolb.2020.00025	https://doi.org/10.3389/fmolb.2020.00025	PROPN
dti-2638	402	27	https://www.ncbi.nlm.nih.gov/pubmed/32181260	https://www.ncbi.nlm.nih.gov/pubmed/32181260	PROPN
dti-2638	402	28	https://doi.org/10.1021/ml500459f	https://doi.org/10.1021/ml500459f	PROPN
dti-2638	402	29	https://www.ncbi.nlm.nih.gov/pubmed/25699144	https://www.ncbi.nlm.nih.gov/pubmed/25699144	PROPN
dti-2638	402	30	https://doi.org/10.1038/nrmicro727	https://doi.org/10.1038/nrmicro727	PROPN
dti-2638	402	31	https://www.ncbi.nlm.nih.gov/pubmed/15040181	https://www.ncbi.nlm.nih.gov/pubmed/15040181	PRON
dti-2638	402	32	https://doi.org/10.1038/nrmicro3232	https://doi.org/10.1038/nrmicro3232	PROPN
dti-2638	402	33	https://www.ncbi.nlm.nih.gov/pubmed/24625893	https://www.ncbi.nlm.nih.gov/pubmed/24625893	NUM