id	sid	tid	token	lemma	pos
dti-3574	1	1	microsoft	microsoft	PROPN
dti-3574	1	2	word	word	PROPN
dti-3574	1	3	g	g	PROPN
dti-3574	1	4	-	-	PUNCT
dti-3574	1	5	baicalein+supplementary+files	baicalein+supplementary+file	NOUN
dti-3574	1	6	drug	drug	NOUN
dti-3574	1	7	target	target	NOUN
dti-3574	1	8	insights	insight	NOUN
dti-3574	1	9	2025	2025	NUM
dti-3574	1	10	|	|	ADV
dti-3574	1	11	doi	doi	NOUN
dti-3574	1	12	:	:	PUNCT
dti-3574	1	13	10.33393	10.33393	NUM
dti-3574	1	14	/	/	SYM
dti-3574	1	15	dti.2025.3574	dti.2025.3574	PROPN
dti-3574	1	16	|	|	ADV
dti-3574	1	17	mishra	mishra	PROPN
dti-3574	1	18	et	et	PROPN
dti-3574	1	19	al	al	PROPN
dti-3574	1	20	1	1	NUM
dti-3574	1	21	supporting	support	VERB
dti-3574	1	22	information	information	NOUN
dti-3574	1	23	supplementary	supplementary	ADJ
dti-3574	1	24	tables	table	NOUN
dti-3574	1	25	table	table	NOUN
dti-3574	1	26	s	s	PROPN
dti-3574	1	27	-	-	PUNCT
dti-3574	1	28	i.	i.	NOUN
dti-3574	1	29	pubchem	pubchem	NOUN
dti-3574	1	30	i	i	PROPN
dti-3574	1	31	d	d	PROPN
dti-3574	1	32	and	and	CCONJ
dti-3574	1	33	canonical	canonical	ADJ
dti-3574	1	34	smiles	smile	NOUN
dti-3574	1	35	of	of	ADP
dti-3574	1	36	baicalein	baicalein	NOUN
dti-3574	1	37	and	and	CCONJ
dti-3574	1	38	reference	reference	NOUN
dti-3574	1	39	compounds	compound	VERB
dti-3574	1	40	ligands	ligand	NOUN
dti-3574	1	41	name	name	NOUN
dti-3574	1	42	of	of	ADP
dti-3574	1	43	ligands	ligand	NOUN
dti-3574	1	44	synonyms	synonym	NOUN
dti-3574	1	45	pubchem	pubchem	NOUN
dti-3574	1	46	i	i	PROPN
dti-3574	1	47	d	d	PROPN
dti-3574	1	48	canonical	canonical	PROPN
dti-3574	1	49	smiles	smile	VERB
dti-3574	1	50	a	a	DET
dti-3574	1	51	baicalein	baicalein	ADJ
dti-3574	1	52	noroxylin	noroxylin	NOUN
dti-3574	1	53	5281605	5281605	NUM
dti-3574	1	54	c1	c1	PROPN
dti-3574	1	55	=	=	SYM
dti-3574	1	56	cc	cc	PROPN
dti-3574	1	57	=	=	NOUN
dti-3574	1	58	c(c	c(c	NOUN
dti-3574	1	59	=	=	ADJ
dti-3574	1	60	c1)c2	c1)c2	PROPN
dti-3574	1	61	=	=	PROPN
dti-3574	1	62	cc(=o)c3	cc(=o)c3	PROPN
dti-3574	1	63	=	=	PRON
dti-3574	1	64	c(o	c(o	VERB
dti-3574	1	65	2)c	2)c	NOUN
dti-3574	1	66	=	=	NOUN
dti-3574	1	67	c(c(=c3o)o)o	c(c(=c3o)o)o	PROPN
dti-3574	1	68	b	b	PROPN
dti-3574	1	69	1,5	1,5	NUM
dti-3574	1	70	-	-	PUNCT
dti-3574	1	71	naphthyridine	naphthyridine	ADJ
dti-3574	1	72	1,5pyridopyridine	1,5pyridopyridine	NUM
dti-3574	1	73	136070	136070	NUM
dti-3574	1	74	c1	c1	NOUN
dti-3574	1	75	=	=	SYM
dti-3574	1	76	cc2	cc2	PROPN
dti-3574	1	77	=	=	PROPN
dti-3574	1	78	c(c	c(c	PROPN
dti-3574	1	79	=	=	ADJ
dti-3574	1	80	cc	cc	NOUN
dti-3574	1	81	=	=	NOUN
dti-3574	1	82	n2)n	n2)n	ADJ
dti-3574	1	83	=	=	PROPN
dti-3574	1	84	c1	c1	PROPN
dti-3574	1	85	c	c	PROPN
dti-3574	1	86	4-(4-(benzo[d][1,3]dioxol-5yl)-5-(1yridine-2	4-(4-(benzo[d][1,3]dioxol-5yl)-5-(1yridine-2	PROPN
dti-3574	1	87	-	-	PUNCT
dti-3574	1	88	yl)-1himidazol-2	yl)-1himidazol-2	NOUN
dti-3574	1	89	-	-	PUNCT
dti-3574	1	90	yl)benzamide	yl)benzamide	NOUN
dti-3574	1	91	sb431542	sb431542	PROPN
dti-3574	1	92	4521392	4521392	NUM
dti-3574	1	93	c1oc2	c1oc2	NOUN
dti-3574	1	94	=	=	ADJ
dti-3574	1	95	c(o1)c	c(o1)c	NOUN
dti-3574	1	96	=	=	NOUN
dti-3574	1	97	c(c	c(c	NOUN
dti-3574	1	98	=	=	ADJ
dti-3574	1	99	c2)c3	c2)c3	NOUN
dti-3574	1	100	=	=	SYM
dti-3574	1	101	c(nc	c(nc	X
dti-3574	1	102	(	(	PUNCT
dti-3574	1	103	=	=	NOUN
dti-3574	1	104	n3)c4	n3)c4	ADJ
dti-3574	1	105	=	=	NOUN
dti-3574	1	106	cc	cc	NOUN
dti-3574	1	107	=	=	NOUN
dti-3574	1	108	c(c	c(c	NOUN
dti-3574	1	109	=	=	NOUN
dti-3574	1	110	c4)c(=o)n)c5	c4)c(=o)n)c5	NOUN
dti-3574	1	111	=	=	NOUN
dti-3574	1	112	c	c	NOUN
dti-3574	1	113	c	c	NOUN
dti-3574	1	114	=	=	SYM
dti-3574	1	115	cc	cc	NOUN
dti-3574	1	116	=	=	PROPN
dti-3574	1	117	n5	n5	PROPN
dti-3574	1	118	d	d	PROPN
dti-3574	1	119	5-[(3s)-5,5	5-[(3s)-5,5	NUM
dti-3574	1	120	-	-	PUNCT
dti-3574	1	121	dimethyloxolan-3yl]-6	dimethyloxolan-3yl]-6	NOUN
dti-3574	1	122	-	-	PUNCT
dti-3574	1	123	methoxy-3-(2methoxypyridin-4yl)pyrazolo[1,5	methoxy-3-(2methoxypyridin-4yl)pyrazolo[1,5	PROPN
dti-3574	1	124	-	-	PUNCT
dti-3574	1	125	a]pyrimidine	a]pyrimidine	NOUN
dti-3574	1	126	chembl47924	chembl47924	PROPN
dti-3574	1	127	64	64	NUM
dti-3574	1	128	156022737	156022737	NUM
dti-3574	1	129	cc1(c[c@h](co1)c2	cc1(c[c@h](co1)c2	X
dti-3574	1	130	=	=	SYM
dti-3574	2	1	nc3	nc3	PROPN
dti-3574	2	2	=	=	NOUN
dti-3574	2	3	c(c	c(c	NOUN
dti-3574	2	4	=	=	NOUN
dti-3574	2	5	n	n	PRON
dti-3574	2	6	n3c	n3c	NOUN
dti-3574	2	7	=	=	SYM
dti-3574	2	8	c2oc)c4	c2oc)c4	NOUN
dti-3574	2	9	=	=	NOUN
dti-3574	2	10	cc(=nc	cc(=nc	NOUN
dti-3574	2	11	=	=	NOUN
dti-3574	2	12	c4)oc)c	c4)oc)c	NOUN
dti-3574	2	13	table	table	NOUN
dti-3574	2	14	s	s	NOUN
dti-3574	2	15	-	-	PUNCT
dti-3574	2	16	ii	ii	NOUN
dti-3574	2	17	.	.	PUNCT
dti-3574	3	1	ramachandran	ramachandran	PROPN
dti-3574	3	2	plot	plot	PROPN
dti-3574	3	3	statistical	statistical	ADJ
dti-3574	3	4	analysis	analysis	NOUN
dti-3574	3	5	s.n	s.n	PROPN
dti-3574	3	6	.	.	PROPN
dti-3574	3	7	target	target	NOUN
dti-3574	3	8	model	model	NOUN
dti-3574	3	9	region	region	NOUN
dti-3574	3	10	most	most	ADV
dti-3574	3	11	favoured	favour	VERB
dti-3574	3	12	additional	additional	ADJ
dti-3574	3	13	allowed	allowed	AUX
dti-3574	3	14	generously	generously	ADV
dti-3574	3	15	allowed	allow	VERB
dti-3574	3	16	disallowed	disallow	VERB
dti-3574	3	17	1	1	NUM
dti-3574	3	18	.	.	PUNCT
dti-3574	4	1	1vjy	1vjy	NUM
dti-3574	4	2	90.7	90.7	NUM
dti-3574	4	3	%	%	NOUN
dti-3574	4	4	9.3	9.3	NUM
dti-3574	4	5	%	%	NOUN
dti-3574	4	6	0.0	0.0	NUM
dti-3574	4	7	%	%	NOUN
dti-3574	4	8	0.0	0.0	NUM
dti-3574	4	9	%	%	NOUN
dti-3574	4	10	2	2	NUM
dti-3574	4	11	.	.	PUNCT
dti-3574	5	1	3tzm	3tzm	NOUN
dti-3574	5	2	92.5	92.5	NUM
dti-3574	5	3	%	%	NOUN
dti-3574	5	4	7.5	7.5	NUM
dti-3574	5	5	%	%	NOUN
dti-3574	5	6	0.0	0.0	NUM
dti-3574	5	7	%	%	NOUN
dti-3574	5	8	0.0	0.0	NUM
dti-3574	5	9	%	%	NOUN
dti-3574	5	10	3	3	NUM
dti-3574	5	11	.	.	NUM
dti-3574	5	12	7dv6	7dv6	NUM
dti-3574	5	13	95.3	95.3	NUM
dti-3574	5	14	%	%	NOUN
dti-3574	5	15	4.7	4.7	NUM
dti-3574	5	16	%	%	NOUN
dti-3574	5	17	0.0	0.0	NUM
dti-3574	5	18	%	%	NOUN
dti-3574	5	19	0.0	0.0	NUM
dti-3574	5	20	%	%	NOUN
dti-3574	5	21	table	table	NOUN
dti-3574	5	22	s	s	NOUN
dti-3574	5	23	-	-	PUNCT
dti-3574	5	24	iii	iii	NOUN
dti-3574	5	25	.	.	PUNCT
dti-3574	6	1	swiss	swiss	ADJ
dti-3574	6	2	adme	adme	NOUN
dti-3574	6	3	and	and	CCONJ
dti-3574	6	4	drug	drug	NOUN
dti-3574	6	5	-	-	PUNCT
dti-3574	6	6	likeness	likeness	NOUN
dti-3574	6	7	prediction	prediction	NOUN
dti-3574	6	8	summary	summary	NOUN
dti-3574	6	9	s.	s.	PROPN
dti-3574	6	10	n.	n.	PROPN
dti-3574	6	11	adme	adme	VERB
dti-3574	6	12	parameters	parameter	NOUN
dti-3574	6	13	baicalein	baicalein	VERB
dti-3574	6	14	physicochemical	physicochemical	ADJ
dti-3574	6	15	properties	property	NOUN
dti-3574	6	16	1	1	NUM
dti-3574	6	17	.	.	X
dti-3574	7	1	formula	formula	VERB
dti-3574	7	2	c15h10o5	c15h10o5	PROPN
dti-3574	7	3	drug	drug	NOUN
dti-3574	7	4	target	target	NOUN
dti-3574	7	5	insights	insight	NOUN
dti-3574	7	6	2025	2025	NUM
dti-3574	7	7	|	|	ADV
dti-3574	7	8	doi	doi	NOUN
dti-3574	7	9	:	:	PUNCT
dti-3574	7	10	10.33393	10.33393	NUM
dti-3574	7	11	/	/	SYM
dti-3574	7	12	dti.2025.3574	dti.2025.3574	PROPN
dti-3574	7	13	|	|	ADV
dti-3574	7	14	mishra	mishra	PROPN
dti-3574	7	15	et	et	PROPN
dti-3574	7	16	al	al	PROPN
dti-3574	7	17	2	2	NUM
dti-3574	7	18	2	2	NUM
dti-3574	7	19	.	.	PUNCT
dti-3574	7	20	molecular	molecular	ADJ
dti-3574	7	21	weight	weight	NOUN
dti-3574	7	22	(	(	PUNCT
dti-3574	7	23	g	g	NOUN
dti-3574	7	24	/	/	SYM
dti-3574	7	25	mol	mol	NOUN
dti-3574	7	26	)	)	PUNCT
dti-3574	7	27	270.24	270.24	NUM
dti-3574	7	28	3	3	NUM
dti-3574	7	29	.	.	PUNCT
dti-3574	8	1	num	num	ADJ
dti-3574	8	2	.	.	PUNCT
dti-3574	9	1	heavy	heavy	ADJ
dti-3574	9	2	atoms	atom	NOUN
dti-3574	9	3	20	20	NUM
dti-3574	9	4	4	4	NUM
dti-3574	9	5	.	.	PUNCT
dti-3574	10	1	num	num	ADJ
dti-3574	10	2	.	.	PUNCT
dti-3574	11	1	arom	arom	ADJ
dti-3574	11	2	.	.	PUNCT
dti-3574	12	1	heavy	heavy	ADJ
dti-3574	12	2	atoms	atom	NOUN
dti-3574	12	3	16	16	NUM
dti-3574	12	4	5	5	NUM
dti-3574	12	5	.	.	PUNCT
dti-3574	12	6	fraction	fraction	NOUN
dti-3574	12	7	csp3	csp3	NOUN
dti-3574	12	8	0.00	0.00	NUM
dti-3574	12	9	6	6	NUM
dti-3574	12	10	.	.	PUNCT
dti-3574	13	1	num	num	ADJ
dti-3574	13	2	.	.	PUNCT
dti-3574	13	3	rotatable	rotatable	ADJ
dti-3574	13	4	bonds	bond	NOUN
dti-3574	13	5	1	1	NUM
dti-3574	13	6	7	7	NUM
dti-3574	13	7	.	.	PUNCT
dti-3574	14	1	num	num	ADJ
dti-3574	14	2	.	.	PUNCT
dti-3574	15	1	h	h	NOUN
dti-3574	15	2	-	-	PUNCT
dti-3574	15	3	bond	bond	NOUN
dti-3574	15	4	acceptors	acceptor	NOUN
dti-3574	15	5	5	5	NUM
dti-3574	15	6	8	8	NUM
dti-3574	15	7	.	.	PUNCT
dti-3574	16	1	num	num	ADJ
dti-3574	16	2	.	.	PUNCT
dti-3574	17	1	h	h	NOUN
dti-3574	17	2	-	-	PUNCT
dti-3574	17	3	bond	bond	NOUN
dti-3574	17	4	donors	donor	NOUN
dti-3574	17	5	3	3	NUM
dti-3574	17	6	9	9	NUM
dti-3574	17	7	.	.	PUNCT
dti-3574	17	8	molar	molar	ADJ
dti-3574	17	9	refractivity	refractivity	NOUN
dti-3574	17	10	(	(	PUNCT
dti-3574	17	11	mr	mr	PROPN
dti-3574	17	12	)	)	PUNCT
dti-3574	17	13	73.99	73.99	NUM
dti-3574	17	14	10	10	NUM
dti-3574	17	15	.	.	PUNCT
dti-3574	18	1	tpsa	tpsa	NOUN
dti-3574	18	2	(	(	PUNCT
dti-3574	18	3	å²	å²	PROPN
dti-3574	18	4	)	)	PUNCT
dti-3574	18	5	90.90	90.90	NUM
dti-3574	18	6	lipophilicity	lipophilicity	NOUN
dti-3574	18	7	11	11	NUM
dti-3574	18	8	.	.	PUNCT
dti-3574	19	1	log	log	VERB
dti-3574	19	2	po	po	PROPN
dti-3574	19	3	/	/	SYM
dti-3574	19	4	w	w	PROPN
dti-3574	19	5	(	(	PUNCT
dti-3574	19	6	ilogp	ilogp	PROPN
dti-3574	19	7	)	)	PUNCT
dti-3574	19	8	2.43	2.43	NUM
dti-3574	19	9	12	12	NUM
dti-3574	19	10	.	.	PUNCT
dti-3574	20	1	log	log	PROPN
dti-3574	20	2	po	po	PROPN
dti-3574	20	3	/	/	SYM
dti-3574	20	4	w	w	PROPN
dti-3574	20	5	(	(	PUNCT
dti-3574	20	6	xlogp3	xlogp3	PROPN
dti-3574	20	7	)	)	PUNCT
dti-3574	20	8	3.16	3.16	NUM
dti-3574	20	9	13	13	NUM
dti-3574	20	10	.	.	PUNCT
dti-3574	21	1	log	log	VERB
dti-3574	21	2	po	po	PROPN
dti-3574	21	3	/	/	SYM
dti-3574	21	4	w	w	PROPN
dti-3574	21	5	(	(	PUNCT
dti-3574	21	6	wlogp	wlogp	NOUN
dti-3574	21	7	)	)	PUNCT
dti-3574	21	8	2.58	2.58	NUM
dti-3574	21	9	water	water	NOUN
dti-3574	21	10	solubility	solubility	NOUN
dti-3574	21	11	14	14	NUM
dti-3574	21	12	.	.	PUNCT
dti-3574	22	1	log	log	PROPN
dti-3574	22	2	s	s	PART
dti-3574	22	3	(	(	PUNCT
dti-3574	22	4	esol	esol	X
dti-3574	22	5	)	)	PUNCT
dti-3574	22	6	-4.0	-4.0	PROPN
dti-3574	22	7	15	15	NUM
dti-3574	22	8	.	.	PUNCT
dti-3574	23	1	qualitative	qualitative	ADJ
dti-3574	23	2	solubility	solubility	NOUN
dti-3574	23	3	moderately	moderately	ADV
dti-3574	23	4	soluble	soluble	ADJ
dti-3574	23	5	pharmacokinetics	pharmacokinetic	NOUN
dti-3574	23	6	16	16	NUM
dti-3574	23	7	.	.	PUNCT
dti-3574	24	1	gi	gi	VERB
dti-3574	24	2	absorption	absorption	PROPN
dti-3574	24	3	high	high	ADJ
dti-3574	24	4	17	17	NUM
dti-3574	24	5	.	.	PUNCT
dti-3574	25	1	intestinal	intestinal	ADJ
dti-3574	25	2	absorption	absorption	NOUN
dti-3574	25	3	(	(	PUNCT
dti-3574	25	4	human	human	NOUN
dti-3574	25	5	)	)	PUNCT
dti-3574	25	6	*	*	PUNCT
dti-3574	26	1	90.14	90.14	NUM
dti-3574	26	2	%	%	NOUN
dti-3574	26	3	18	18	NUM
dti-3574	26	4	.	.	PUNCT
dti-3574	26	5	bbb	bbb	PROPN
dti-3574	26	6	permeant	permeant	PROPN
dti-3574	26	7	no	no	DET
dti-3574	26	8	19	19	NUM
dti-3574	26	9	.	.	PUNCT
dti-3574	27	1	p	p	X
dti-3574	27	2	-	-	PUNCT
dti-3574	27	3	gp	gp	NOUN
dti-3574	27	4	substrate	substrate	NOUN
dti-3574	27	5	no	no	DET
dti-3574	27	6	20	20	NUM
dti-3574	27	7	.	.	PUNCT
dti-3574	28	1	cyp1a2	cyp1a2	ADJ
dti-3574	28	2	inhibitor	inhibitor	NOUN
dti-3574	28	3	yes	yes	INTJ
dti-3574	28	4	21	21	NUM
dti-3574	28	5	.	.	PUNCT
dti-3574	29	1	cyp2c19	cyp2c19	NOUN
dti-3574	29	2	inhibitor	inhibitor	NOUN
dti-3574	29	3	no	no	DET
dti-3574	29	4	22	22	NUM
dti-3574	29	5	.	.	PUNCT
dti-3574	30	1	cyp2c9	cyp2c9	NOUN
dti-3574	30	2	inhibitor	inhibitor	NOUN
dti-3574	30	3	no	no	DET
dti-3574	30	4	23	23	NUM
dti-3574	30	5	.	.	PUNCT
dti-3574	31	1	cyp2d6	cyp2d6	NOUN
dti-3574	31	2	inhibitor	inhibitor	NOUN
dti-3574	31	3	yes	yes	INTJ
dti-3574	31	4	24	24	NUM
dti-3574	31	5	.	.	PUNCT
dti-3574	32	1	cyp3a4	cyp3a4	PROPN
dti-3574	32	2	inhibitor	inhibitor	NOUN
dti-3574	33	1	yes	yes	INTJ
dti-3574	33	2	25	25	NUM
dti-3574	33	3	.	.	PUNCT
dti-3574	34	1	log	log	PROPN
dti-3574	34	2	kp	kp	PROPN
dti-3574	34	3	(	(	PUNCT
dti-3574	34	4	skin	skin	NOUN
dti-3574	34	5	permeation	permeation	NOUN
dti-3574	34	6	)	)	PUNCT
dti-3574	34	7	(	(	PUNCT
dti-3574	34	8	cm	cm	NOUN
dti-3574	34	9	/	/	SYM
dti-3574	34	10	s	s	NOUN
dti-3574	34	11	)	)	PUNCT
dti-3574	34	12	-5.70	-5.70	NUM
dti-3574	34	13	26	26	NUM
dti-3574	34	14	.	.	PUNCT
dti-3574	35	1	skin	skin	NOUN
dti-3574	35	2	permeability	permeability	NOUN
dti-3574	35	3	(	(	PUNCT
dti-3574	35	4	log	log	NOUN
dti-3574	35	5	kp	kp	NOUN
dti-3574	35	6	)	)	PUNCT
dti-3574	35	7	*	*	PROPN
dti-3574	35	8	-3.433	-3.433	PUNCT
dti-3574	36	1	27	27	NUM
dti-3574	36	2	.	.	PUNCT
dti-3574	37	1	total	total	ADJ
dti-3574	37	2	clearance	clearance	NOUN
dti-3574	37	3	(	(	PUNCT
dti-3574	37	4	log	log	VERB
dti-3574	37	5	ml	ml	NOUN
dti-3574	37	6	/	/	SYM
dti-3574	37	7	min	min	NOUN
dti-3574	37	8	/	/	SYM
dti-3574	37	9	kg	kg	NOUN
dti-3574	37	10	)	)	PUNCT
dti-3574	37	11	*	*	PUNCT
dti-3574	37	12	0.273	0.273	NUM
dti-3574	37	13	28	28	NUM
dti-3574	37	14	.	.	PUNCT
dti-3574	38	1	renal	renal	ADJ
dti-3574	38	2	oct2	oct2	NOUN
dti-3574	38	3	#	#	NOUN
dti-3574	38	4	substrate	substrate	NOUN
dti-3574	38	5	*	*	VERB
dti-3574	38	6	no	no	DET
dti-3574	38	7	drug	drug	NOUN
dti-3574	38	8	-	-	PUNCT
dti-3574	38	9	likeness	likeness	NOUN
dti-3574	38	10	29	29	NUM
dti-3574	38	11	.	.	PUNCT
dti-3574	39	1	lipinski	lipinski	PROPN
dti-3574	39	2	(	(	PUNCT
dti-3574	39	3	ro5	ro5	PROPN
dti-3574	39	4	)	)	PUNCT
dti-3574	39	5	yes	yes	INTJ
dti-3574	39	6	;	;	PUNCT
dti-3574	39	7	0	0	NUM
dti-3574	39	8	violation	violation	NOUN
dti-3574	39	9	30	30	NUM
dti-3574	39	10	.	.	PUNCT
dti-3574	40	1	ghose	ghose	PROPN
dti-3574	40	2	yes	yes	INTJ
dti-3574	41	1	31	31	NUM
dti-3574	41	2	.	.	PUNCT
dti-3574	42	1	veber	veber	PROPN
dti-3574	43	1	yes	yes	INTJ
dti-3574	44	1	32	32	NUM
dti-3574	44	2	.	.	PUNCT
dti-3574	45	1	bioavailability	bioavailability	NOUN
dti-3574	45	2	score	score	NOUN
dti-3574	45	3	0.55	0.55	NUM
dti-3574	45	4	33	33	NUM
dti-3574	45	5	.	.	PUNCT
dti-3574	46	1	lead	lead	NOUN
dti-3574	46	2	-	-	PUNCT
dti-3574	46	3	likeness	likeness	NOUN
dti-3574	47	1	yes	yes	INTJ
dti-3574	47	2	34	34	NUM
dti-3574	47	3	.	.	PUNCT
dti-3574	48	1	sa	sa	PROPN
dti-3574	48	2	3.02	3.02	NUM
dti-3574	48	3	drug	drug	NOUN
dti-3574	48	4	target	target	NOUN
dti-3574	48	5	insights	insight	NOUN
dti-3574	48	6	2025	2025	NUM
dti-3574	48	7	|	|	ADV
dti-3574	48	8	doi	doi	NOUN
dti-3574	48	9	:	:	PUNCT
dti-3574	48	10	10.33393	10.33393	NUM
dti-3574	48	11	/	/	SYM
dti-3574	48	12	dti.2025.3574	dti.2025.3574	PROPN
dti-3574	48	13	|	|	ADV
dti-3574	48	14	mishra	mishra	PROPN
dti-3574	48	15	et	et	PROPN
dti-3574	48	16	al	al	PROPN
dti-3574	48	17	3	3	NUM
dti-3574	48	18	fraction	fraction	NOUN
dti-3574	48	19	csp3	csp3	NOUN
dti-3574	48	20	:	:	PUNCT
dti-3574	48	21	fraction	fraction	NOUN
dti-3574	48	22	of	of	ADP
dti-3574	48	23	carbon	carbon	NOUN
dti-3574	48	24	atoms	atom	NOUN
dti-3574	48	25	that	that	PRON
dti-3574	48	26	are	be	AUX
dti-3574	48	27	sp3	sp3	ADV
dti-3574	48	28	hybridised	hybridise	VERB
dti-3574	48	29	;	;	PUNCT
dti-3574	48	30	tpsa	tpsa	NOUN
dti-3574	48	31	:	:	PUNCT
dti-3574	48	32	topological	topological	ADJ
dti-3574	48	33	polar	polar	ADJ
dti-3574	48	34	surface	surface	NOUN
dti-3574	48	35	area	area	NOUN
dti-3574	48	36	;	;	PUNCT
dti-3574	48	37	log	log	VERB
dti-3574	48	38	po	po	NOUN
dti-3574	48	39	/	/	SYM
dti-3574	48	40	w	w	NOUN
dti-3574	48	41	:	:	PUNCT
dti-3574	48	42	partition	partition	NOUN
dti-3574	48	43	coefficient	coefficient	NOUN
dti-3574	48	44	between	between	ADP
dti-3574	48	45	n	n	NOUN
dti-3574	48	46	-	-	PUNCT
dti-3574	48	47	octanol	octanol	NOUN
dti-3574	48	48	and	and	CCONJ
dti-3574	48	49	water	water	NOUN
dti-3574	48	50	;	;	PUNCT
dti-3574	48	51	log	log	NOUN
dti-3574	48	52	s	s	PART
dti-3574	48	53	:	:	PUNCT
dti-3574	48	54	decimal	decimal	ADJ
dti-3574	48	55	logarithm	logarithm	NOUN
dti-3574	48	56	of	of	ADP
dti-3574	48	57	the	the	DET
dti-3574	48	58	molar	molar	ADJ
dti-3574	48	59	solubility	solubility	NOUN
dti-3574	48	60	in	in	ADP
dti-3574	48	61	water	water	NOUN
dti-3574	48	62	;	;	PUNCT
dti-3574	48	63	lipinski	lipinski	PROPN
dti-3574	48	64	(	(	PUNCT
dti-3574	48	65	ro5	ro5	PROPN
dti-3574	48	66	)	)	PUNCT
dti-3574	48	67	:	:	PUNCT
dti-3574	48	68	range	range	NOUN
dti-3574	48	69	are	be	AUX
dti-3574	48	70	mw	mw	VERB
dti-3574	48	71	≤	≤	NUM
dti-3574	48	72	500	500	NUM
dti-3574	48	73	,	,	PUNCT
dti-3574	48	74	mlogp	mlogp	ADJ
dti-3574	48	75	≤	≤	NOUN
dti-3574	48	76	4.15	4.15	NUM
dti-3574	48	77	,	,	PUNCT
dti-3574	48	78	n	n	NOUN
dti-3574	48	79	or	or	CCONJ
dti-3574	48	80	o	o	X
dti-3574	48	81	≤	≤	NUM
dti-3574	48	82	10	10	NUM
dti-3574	48	83	,	,	PUNCT
dti-3574	48	84	nh	nh	PROPN
dti-3574	48	85	or	or	CCONJ
dti-3574	48	86	oh	oh	INTJ
dti-3574	48	87	≤	≤	NUM
dti-3574	48	88	5	5	NUM
dti-3574	48	89	;	;	PUNCT
dti-3574	48	90	ghose	ghose	PROPN
dti-3574	48	91	:	:	PUNCT
dti-3574	48	92	range	range	VERB
dti-3574	48	93	160	160	NUM
dti-3574	48	94	≤	≤	NUM
dti-3574	48	95	mw	mw	VERB
dti-3574	48	96	≤	≤	NUM
dti-3574	48	97	480	480	NUM
dti-3574	48	98	,	,	PUNCT
dti-3574	48	99	-0.4	-0.4	NUM
dti-3574	48	100	≤	≤	NUM
dti-3574	48	101	wlogp	wlogp	VERB
dti-3574	48	102	≤	≤	ADJ
dti-3574	48	103	5.6	5.6	NUM
dti-3574	48	104	,	,	PUNCT
dti-3574	48	105	40	40	NUM
dti-3574	48	106	≤	≤	NOUN
dti-3574	48	107	mr	mr	PROPN
dti-3574	48	108	≤	≤	PROPN
dti-3574	48	109	130	130	NUM
dti-3574	48	110	,	,	PUNCT
dti-3574	48	111	20	20	NUM
dti-3574	48	112	≤	≤	NUM
dti-3574	48	113	atoms	atom	NOUN
dti-3574	48	114	≤	≤	NUM
dti-3574	48	115	70	70	NUM
dti-3574	48	116	;	;	PUNCT
dti-3574	48	117	veber	veber	PROPN
dti-3574	48	118	’s	’s	PART
dti-3574	48	119	rule	rule	NOUN
dti-3574	48	120	:	:	PUNCT
dti-3574	48	121	range	range	NOUN
dti-3574	48	122	are	be	AUX
dti-3574	48	123	rotatable	rotatable	ADJ
dti-3574	48	124	bonds	bond	NOUN
dti-3574	48	125	≤	≤	ADV
dti-3574	48	126	10	10	NUM
dti-3574	48	127	,	,	PUNCT
dti-3574	48	128	tpsa	tpsa	NOUN
dti-3574	48	129	≤	≤	NOUN
dti-3574	48	130	140	140	NUM
dti-3574	48	131	;	;	PUNCT
dti-3574	48	132	sa	sa	NOUN
dti-3574	48	133	:	:	PUNCT
dti-3574	48	134	synthetic	synthetic	ADJ
dti-3574	48	135	accessibility	accessibility	NOUN
dti-3574	48	136	score	score	NOUN
dti-3574	48	137	ranges	range	VERB
dti-3574	48	138	from	from	ADP
dti-3574	48	139	1	1	NUM
dti-3574	48	140	(	(	PUNCT
dti-3574	48	141	very	very	ADV
dti-3574	48	142	easy	easy	ADJ
dti-3574	48	143	)	)	PUNCT
dti-3574	48	144	to	to	ADP
dti-3574	48	145	10	10	NUM
dti-3574	48	146	(	(	PUNCT
dti-3574	48	147	very	very	ADV
dti-3574	48	148	difficult	difficult	ADJ
dti-3574	48	149	)	)	PUNCT
dti-3574	48	150	.	.	PUNCT
dti-3574	49	1	*	*	PUNCT
dti-3574	49	2	according	accord	VERB
dti-3574	49	3	to	to	ADP
dti-3574	49	4	pkcsm	pkcsm	NOUN
dti-3574	49	5	biosig	biosig	PRON
dti-3574	49	6	lab	lab	NOUN
dti-3574	49	7	prediction	prediction	NOUN
dti-3574	49	8	tool	tool	NOUN
dti-3574	49	9	.	.	PUNCT
dti-3574	50	1	#	#	NOUN
dti-3574	50	2	oct2	oct2	NOUN
dti-3574	50	3	:	:	PUNCT
dti-3574	50	4	organic	organic	ADJ
dti-3574	50	5	cation	cation	NOUN
dti-3574	50	6	transporter	transporter	NOUN
dti-3574	50	7	2	2	NUM
dti-3574	50	8	drug	drug	NOUN
dti-3574	50	9	target	target	NOUN
dti-3574	50	10	insights	insight	NOUN
dti-3574	50	11	2025	2025	NUM
dti-3574	50	12	|	|	ADV
dti-3574	50	13	doi	doi	NOUN
dti-3574	50	14	:	:	PUNCT
dti-3574	50	15	10.33393	10.33393	NUM
dti-3574	50	16	/	/	SYM
dti-3574	50	17	dti.2025.3574	dti.2025.3574	PROPN
dti-3574	50	18	|	|	ADV
dti-3574	50	19	mishra	mishra	PROPN
dti-3574	50	20	et	et	PROPN
dti-3574	50	21	al	al	PROPN
dti-3574	50	22	4	4	NUM
dti-3574	50	23	table	table	NOUN
dti-3574	50	24	s	s	NOUN
dti-3574	50	25	-	-	PUNCT
dti-3574	50	26	iv	iv	NOUN
dti-3574	50	27	.	.	NOUN
dti-3574	50	28	list	list	NOUN
dti-3574	50	29	of	of	ADP
dti-3574	50	30	the	the	DET
dti-3574	50	31	various	various	ADJ
dti-3574	50	32	targets	target	NOUN
dti-3574	50	33	,	,	PUNCT
dti-3574	50	34	baicalein	baicalein	NOUN
dti-3574	50	35	may	may	AUX
dti-3574	50	36	bind	bind	VERB
dti-3574	50	37	with	with	ADP
dti-3574	50	38	probable	probable	ADJ
dti-3574	50	39	score	score	NOUN
dti-3574	50	40	ranges	range	VERB
dti-3574	50	41	from	from	ADP
dti-3574	50	42	1.0000	1.0000	NUM
dti-3574	50	43	to	to	ADP
dti-3574	50	44	0.3299	0.3299	NUM
dti-3574	50	45	target	target	NOUN
dti-3574	50	46	common	common	ADJ
dti-3574	50	47	name	name	NOUN
dti-3574	50	48	uniprot	uniprot	PROPN
dti-3574	50	49	i	i	PROPN
dti-3574	50	50	d	d	NOUN
dti-3574	50	51	chembl	chembl	NOUN
dti-3574	50	52	i	i	PROPN
dti-3574	50	53	d	d	PROPN
dti-3574	50	54	target	target	NOUN
dti-3574	50	55	class	class	NOUN
dti-3574	50	56	probability	probability	NOUN
dti-3574	50	57	*	*	PUNCT
dti-3574	50	58	known	know	VERB
dti-3574	50	59	actives	active	NOUN
dti-3574	50	60	(	(	PUNCT
dti-3574	50	61	3d/2d	3d/2d	NUM
dti-3574	50	62	)	)	PUNCT
dti-3574	50	63	lysine	lysine	NOUN
dti-3574	50	64	-	-	PUNCT
dti-3574	50	65	specific	specific	ADJ
dti-3574	50	66	demethylase	demethylase	NOUN
dti-3574	50	67	4d	4d	NOUN
dti-3574	50	68	-	-	PUNCT
dti-3574	50	69	like	like	ADJ
dti-3574	50	70	kdm4e	kdm4e	PROPN
dti-3574	50	71	b2rxh2	b2rxh2	VERB
dti-3574	51	1	chembl1293226	chembl1293226	PROPN
dti-3574	51	2	eraser	eraser	NOUN
dti-3574	51	3	1	1	NUM
dti-3574	51	4	2	2	NUM
dti-3574	51	5	/	/	SYM
dti-3574	51	6	2	2	NUM
dti-3574	51	7	xanthine	xanthine	NOUN
dti-3574	51	8	dehydrogenase	dehydrogenase	NOUN
dti-3574	51	9	xdh	xdh	PROPN
dti-3574	51	10	p47989	p47989	PROPN
dti-3574	51	11	chembl1929	chembl1929	NOUN
dti-3574	51	12	oxidoreductase	oxidoreductase	NOUN
dti-3574	51	13	1	1	NUM
dti-3574	51	14	10	10	NUM
dti-3574	51	15	/	/	SYM
dti-3574	51	16	21	21	NUM
dti-3574	51	17	arachidonate	arachidonate	ADJ
dti-3574	51	18	15	15	NUM
dti-3574	51	19	-	-	PUNCT
dti-3574	51	20	lipoxygenase	lipoxygenase	NOUN
dti-3574	51	21	alox15	alox15	NOUN
dti-3574	51	22	p16050	p16050	PROPN
dti-3574	51	23	chembl2903	chembl2903	PROPN
dti-3574	51	24	enzyme	enzyme	NOUN
dti-3574	51	25	1	1	NUM
dti-3574	51	26	7	7	NUM
dti-3574	51	27	/	/	SYM
dti-3574	51	28	9	9	NUM
dti-3574	51	29	cyclin	cyclin	NOUN
dti-3574	51	30	-	-	PUNCT
dti-3574	51	31	dependent	dependent	ADJ
dti-3574	51	32	kinase	kinase	NOUN
dti-3574	51	33	1	1	NUM
dti-3574	51	34	cdk1	cdk1	PROPN
dti-3574	51	35	p06493	p06493	PROPN
dti-3574	51	36	chembl308	chembl308	PROPN
dti-3574	51	37	kinase	kinase	NOUN
dti-3574	51	38	1	1	NUM
dti-3574	51	39	3	3	NUM
dti-3574	51	40	/	/	SYM
dti-3574	51	41	10	10	NUM
dti-3574	51	42	arachidonate	arachidonate	ADJ
dti-3574	51	43	12	12	NUM
dti-3574	51	44	-	-	PUNCT
dti-3574	51	45	lipoxygenase	lipoxygenase	NOUN
dti-3574	51	46	alox12	alox12	NOUN
dti-3574	51	47	p18054	p18054	NOUN
dti-3574	52	1	chembl3687	chembl3687	ADJ
dti-3574	52	2	enzyme	enzyme	NOUN
dti-3574	52	3	1	1	NUM
dti-3574	52	4	10	10	NUM
dti-3574	52	5	/	/	SYM
dti-3574	52	6	12	12	NUM
dti-3574	52	7	g	g	NOUN
dti-3574	52	8	protein	protein	NOUN
dti-3574	52	9	-	-	PUNCT
dti-3574	52	10	coupled	couple	VERB
dti-3574	52	11	receptor	receptor	NOUN
dti-3574	52	12	kinase	kinase	PROPN
dti-3574	52	13	6	6	NUM
dti-3574	52	14	grk6	grk6	NOUN
dti-3574	52	15	p43250	p43250	NUM
dti-3574	52	16	chembl6144	chembl6144	PROPN
dti-3574	52	17	kinase	kinase	NOUN
dti-3574	52	18	1	1	NUM
dti-3574	52	19	3	3	NUM
dti-3574	52	20	/	/	SYM
dti-3574	52	21	4	4	NUM
dti-3574	52	22	cytochrome	cytochrome	NOUN
dti-3574	52	23	p450	p450	PROPN
dti-3574	52	24	19a1	19a1	NUM
dti-3574	53	1	cyp19a1	cyp19a1	ADJ
dti-3574	53	2	p11511	p11511	PROPN
dti-3574	53	3	chembl1978	chembl1978	PROPN
dti-3574	53	4	cytochrome	cytochrome	NOUN
dti-3574	53	5	p450	p450	NOUN
dti-3574	53	6	0.436430316	0.436430316	NUM
dti-3574	53	7	6	6	NUM
dti-3574	53	8	/	/	SYM
dti-3574	53	9	19	19	NUM
dti-3574	53	10	carbonic	carbonic	ADJ
dti-3574	53	11	anhydrase	anhydrase	NOUN
dti-3574	53	12	vii	vii	PROPN
dti-3574	53	13	ca7	ca7	PROPN
dti-3574	53	14	p43166	p43166	NOUN
dti-3574	53	15	chembl2326	chembl2326	NOUN
dti-3574	53	16	lyase	lyase	VERB
dti-3574	53	17	0.346270483	0.346270483	NUM
dti-3574	53	18	8	8	NUM
dti-3574	53	19	/	/	SYM
dti-3574	53	20	11	11	NUM
dti-3574	53	21	carbonic	carbonic	ADJ
dti-3574	53	22	anhydrase	anhydrase	NOUN
dti-3574	53	23	xii	xii	NOUN
dti-3574	54	1	ca12	ca12	PROPN
dti-3574	54	2	o43570	o43570	NOUN
dti-3574	54	3	chembl3242	chembl3242	PROPN
dti-3574	54	4	lyase	lyase	VERB
dti-3574	54	5	0.346270483	0.346270483	NUM
dti-3574	54	6	13	13	NUM
dti-3574	54	7	/	/	SYM
dti-3574	54	8	16	16	NUM
dti-3574	54	9	carbonic	carbonic	NOUN
dti-3574	54	10	anhydrase	anhydrase	NOUN
dti-3574	54	11	iv	iv	NOUN
dti-3574	54	12	ca4	ca4	NOUN
dti-3574	54	13	p22748	p22748	NOUN
dti-3574	54	14	chembl3729	chembl3729	PROPN
dti-3574	54	15	lyase	lyase	PROPN
dti-3574	54	16	0.346270483	0.346270483	NUM
dti-3574	54	17	9	9	NUM
dti-3574	54	18	/	/	SYM
dti-3574	54	19	11	11	NUM
dti-3574	54	20	p	p	NOUN
dti-3574	54	21	-	-	PUNCT
dti-3574	54	22	glycoprotein	glycoprotein	NOUN
dti-3574	54	23	1	1	NUM
dti-3574	54	24	abcb1	abcb1	NOUN
dti-3574	54	25	p08183	p08183	NOUN
dti-3574	54	26	chembl4302	chembl4302	PROPN
dti-3574	54	27	primary	primary	ADJ
dti-3574	54	28	active	active	ADJ
dti-3574	54	29	transporter	transporter	NOUN
dti-3574	54	30	0.346270483	0.346270483	NUM
dti-3574	54	31	12	12	NUM
dti-3574	54	32	/	/	SYM
dti-3574	54	33	45	45	NUM
dti-3574	54	34	cytochrome	cytochrome	NOUN
dti-3574	54	35	p450	p450	NUM
dti-3574	54	36	1b1	1b1	NUM
dti-3574	54	37	cyp1b1	cyp1b1	NOUN
dti-3574	54	38	q16678	q16678	CCONJ
dti-3574	54	39	chembl4878	chembl4878	PROPN
dti-3574	54	40	cytochrome	cytochrome	NOUN
dti-3574	54	41	p450	p450	NUM
dti-3574	54	42	0.346270483	0.346270483	NUM
dti-3574	54	43	12	12	NUM
dti-3574	54	44	/	/	SYM
dti-3574	54	45	47	47	NUM
dti-3574	54	46	estradiol	estradiol	PROPN
dti-3574	54	47	17	17	NUM
dti-3574	54	48	-	-	PUNCT
dti-3574	54	49	beta	beta	NOUN
dti-3574	54	50	-	-	PUNCT
dti-3574	54	51	dehydrogenase	dehydrogenase	NOUN
dti-3574	54	52	1	1	NUM
dti-3574	54	53	hsd17b1	hsd17b1	NOUN
dti-3574	54	54	p14061	p14061	PROPN
dti-3574	54	55	chembl3181	chembl3181	PROPN
dti-3574	54	56	enzyme	enzyme	VERB
dti-3574	54	57	0.33811031	0.33811031	NUM
dti-3574	54	58	8	8	NUM
dti-3574	54	59	/	/	SYM
dti-3574	54	60	4	4	NUM
dti-3574	54	61	aldose	aldose	PROPN
dti-3574	54	62	reductase	reductase	NOUN
dti-3574	54	63	akr1b1	akr1b1	PROPN
dti-3574	54	64	p15121	p15121	PUNCT
dti-3574	54	65	chembl1900	chembl1900	NOUN
dti-3574	54	66	enzyme	enzyme	NOUN
dti-3574	54	67	0.329868485	0.329868485	NUM
dti-3574	54	68	22	22	NUM
dti-3574	54	69	/	/	SYM
dti-3574	54	70	69	69	NUM
dti-3574	54	71	cyclin	cyclin	NOUN
dti-3574	54	72	-	-	PUNCT
dti-3574	54	73	dependent	dependent	ADJ
dti-3574	54	74	kinase	kinase	NOUN
dti-3574	54	75	5	5	NUM
dti-3574	54	76	/	/	SYM
dti-3574	54	77	cdk5	cdk5	PROPN
dti-3574	54	78	activator	activator	NOUN
dti-3574	54	79	1	1	NUM
dti-3574	54	80	cdk5r1	cdk5r1	NOUN
dti-3574	54	81	cdk5	cdk5	PROPN
dti-3574	55	1	q15078	q15078	PROPN
dti-3574	55	2	q00535	q00535	PROPN
dti-3574	55	3	chembl1907600	chembl1907600	PROPN
dti-3574	55	4	kinase	kinase	NOUN
dti-3574	55	5	0.329868485	0.329868485	NUM
dti-3574	55	6	6	6	NUM
dti-3574	55	7	/	/	SYM
dti-3574	55	8	18	18	NUM
dti-3574	55	9	*	*	NUM
dti-3574	55	10	probability	probability	NOUN
dti-3574	55	11	for	for	ADP
dti-3574	55	12	the	the	DET
dti-3574	55	13	query	query	NOUN
dti-3574	55	14	molecule	molecule	NOUN
dti-3574	55	15	assumed	assume	VERB
dti-3574	55	16	as	as	ADP
dti-3574	55	17	bioactive	bioactive	NOUN
dti-3574	55	18	to	to	PART
dti-3574	55	19	have	have	VERB
dti-3574	55	20	the	the	DET
dti-3574	55	21	protein	protein	NOUN
dti-3574	55	22	as	as	ADP
dti-3574	55	23	target	target	NOUN
dti-3574	55	24	.	.	PUNCT
dti-3574	56	1	drug	drug	NOUN
dti-3574	56	2	target	target	NOUN
dti-3574	56	3	insights	insight	NOUN
dti-3574	56	4	2025	2025	NUM
dti-3574	56	5	|	|	ADV
dti-3574	56	6	doi	doi	NOUN
dti-3574	56	7	:	:	PUNCT
dti-3574	56	8	10.33393	10.33393	NUM
dti-3574	56	9	/	/	SYM
dti-3574	56	10	dti.2025.3574	dti.2025.3574	PROPN
dti-3574	56	11	|	|	ADV
dti-3574	56	12	mishra	mishra	PROPN
dti-3574	56	13	et	et	PROPN
dti-3574	56	14	al	al	PROPN
dti-3574	56	15	5	5	NUM
dti-3574	56	16	table	table	NOUN
dti-3574	56	17	s	s	NOUN
dti-3574	56	18	-	-	ADJ
dti-3574	56	19	v.	v.	ADP
dti-3574	56	20	oral	oral	ADJ
dti-3574	56	21	toxicity	toxicity	NOUN
dti-3574	56	22	model	model	NOUN
dti-3574	56	23	report	report	NOUN
dti-3574	56	24	of	of	ADP
dti-3574	56	25	baicalein	baicalein	PROPN
dti-3574	56	26	classification	classification	NOUN
dti-3574	56	27	target	target	NOUN
dti-3574	56	28	shorthand	shorthand	NOUN
dti-3574	56	29	predictio	predictio	NOUN
dti-3574	56	30	n	n	CCONJ
dti-3574	56	31	probability	probability	NOUN
dti-3574	56	32	organ	organ	NOUN
dti-3574	56	33	toxicity	toxicity	NOUN
dti-3574	56	34	hepatotoxicity	hepatotoxicity	NOUN
dti-3574	56	35	dili	dili	PROPN
dti-3574	56	36	inactive	inactive	ADJ
dti-3574	56	37	0.69	0.69	NUM
dti-3574	56	38	organ	organ	NOUN
dti-3574	56	39	toxicity	toxicity	NOUN
dti-3574	56	40	neurotoxicity	neurotoxicity	NOUN
dti-3574	56	41	neuro	neuro	NOUN
dti-3574	56	42	inactive	inactive	ADJ
dti-3574	56	43	0.89	0.89	NUM
dti-3574	56	44	organ	organ	NOUN
dti-3574	56	45	toxicity	toxicity	NOUN
dti-3574	56	46	nephrotoxicity	nephrotoxicity	NOUN
dti-3574	56	47	nephro	nephro	NOUN
dti-3574	56	48	active	active	ADJ
dti-3574	56	49	0.62	0.62	NUM
dti-3574	56	50	organ	organ	NOUN
dti-3574	56	51	toxicity	toxicity	NOUN
dti-3574	56	52	respiratory	respiratory	ADJ
dti-3574	56	53	toxicity	toxicity	NOUN
dti-3574	56	54	respi	respi	NOUN
dti-3574	56	55	active	active	ADJ
dti-3574	56	56	0.83	0.83	NUM
dti-3574	56	57	organ	organ	NOUN
dti-3574	56	58	toxicity	toxicity	NOUN
dti-3574	56	59	cardiotoxicity	cardiotoxicity	NOUN
dti-3574	56	60	cardio	cardio	NOUN
dti-3574	56	61	inactive	inactive	ADJ
dti-3574	56	62	0.99	0.99	NUM
dti-3574	56	63	toxicity	toxicity	NOUN
dti-3574	56	64	end	end	NOUN
dti-3574	56	65	points	point	NOUN
dti-3574	56	66	carcinogenicity	carcinogenicity	NOUN
dti-3574	56	67	carcino	carcino	NOUN
dti-3574	56	68	active	active	ADJ
dti-3574	56	69	0.68	0.68	NUM
dti-3574	56	70	toxicity	toxicity	NOUN
dti-3574	56	71	end	end	NOUN
dti-3574	56	72	points	point	NOUN
dti-3574	56	73	immunotoxicity	immunotoxicity	NOUN
dti-3574	56	74	immuno	immuno	NOUN
dti-3574	56	75	inactive	inactive	ADJ
dti-3574	56	76	0.99	0.99	NUM
dti-3574	56	77	toxicity	toxicity	NOUN
dti-3574	56	78	end	end	NOUN
dti-3574	56	79	points	point	NOUN
dti-3574	56	80	mutagenicity	mutagenicity	NOUN
dti-3574	56	81	mutagen	mutagen	NOUN
dti-3574	56	82	active	active	ADJ
dti-3574	56	83	0.51	0.51	NUM
dti-3574	56	84	toxicity	toxicity	NOUN
dti-3574	56	85	end	end	NOUN
dti-3574	56	86	points	point	NOUN
dti-3574	56	87	cytotoxicity	cytotoxicity	NOUN
dti-3574	56	88	cyto	cyto	NOUN
dti-3574	56	89	inactive	inactive	ADJ
dti-3574	56	90	0.99	0.99	NUM
dti-3574	56	91	toxicity	toxicity	NOUN
dti-3574	56	92	end	end	NOUN
dti-3574	56	93	points	point	NOUN
dti-3574	56	94	bbb	bbb	NOUN
dti-3574	56	95	-	-	PUNCT
dti-3574	56	96	barrier	barrier	NOUN
dti-3574	56	97	bbb	bbb	PROPN
dti-3574	56	98	active	active	ADJ
dti-3574	56	99	0.53	0.53	NUM
dti-3574	56	100	toxicity	toxicity	NOUN
dti-3574	56	101	end	end	NOUN
dti-3574	56	102	points	point	NOUN
dti-3574	56	103	ecotoxicity	ecotoxicity	NOUN
dti-3574	56	104	eco	eco	NOUN
dti-3574	56	105	inactive	inactive	ADJ
dti-3574	56	106	0.53	0.53	NUM
dti-3574	56	107	toxicity	toxicity	NOUN
dti-3574	56	108	end	end	NOUN
dti-3574	56	109	points	point	VERB
dti-3574	56	110	clinical	clinical	ADJ
dti-3574	56	111	toxicity	toxicity	NOUN
dti-3574	56	112	clinical	clinical	ADJ
dti-3574	56	113	inactive	inactive	ADJ
dti-3574	56	114	0.53	0.53	NUM
dti-3574	56	115	toxicity	toxicity	NOUN
dti-3574	56	116	end	end	NOUN
dti-3574	56	117	points	point	VERB
dti-3574	56	118	nutritional	nutritional	ADJ
dti-3574	56	119	toxicity	toxicity	NOUN
dti-3574	56	120	nutri	nutri	NOUN
dti-3574	56	121	active	active	ADJ
dti-3574	56	122	0.63	0.63	NUM
dti-3574	56	123	tox21	tox21	PROPN
dti-3574	56	124	-	-	PUNCT
dti-3574	56	125	nuclear	nuclear	ADJ
dti-3574	56	126	receptor	receptor	NOUN
dti-3574	56	127	signalling	signal	VERB
dti-3574	56	128	pathways	pathways	ADJ
dti-3574	56	129	aryl	aryl	NOUN
dti-3574	56	130	hydrocarbon	hydrocarbon	NOUN
dti-3574	56	131	receptor	receptor	NOUN
dti-3574	56	132	(	(	PUNCT
dti-3574	56	133	ahr	ahr	PROPN
dti-3574	56	134	)	)	PUNCT
dti-3574	56	135	nr_ahr	nr_ahr	SCONJ
dti-3574	57	1	active	active	ADJ
dti-3574	57	2	0.91	0.91	NUM
dti-3574	57	3	tox21	tox21	PROPN
dti-3574	57	4	-	-	PUNCT
dti-3574	57	5	nuclear	nuclear	ADJ
dti-3574	57	6	receptor	receptor	NOUN
dti-3574	57	7	signalling	signal	VERB
dti-3574	57	8	pathways	pathway	NOUN
dti-3574	57	9	androgen	androgen	NOUN
dti-3574	57	10	receptor	receptor	NOUN
dti-3574	57	11	(	(	PUNCT
dti-3574	57	12	ar	ar	NOUN
dti-3574	57	13	)	)	PUNCT
dti-3574	57	14	nr_ar	nr_ar	NOUN
dti-3574	57	15	inactive	inactive	ADJ
dti-3574	57	16	0.99	0.99	NUM
dti-3574	57	17	tox21	tox21	NOUN
dti-3574	57	18	-	-	PUNCT
dti-3574	57	19	nuclear	nuclear	ADJ
dti-3574	57	20	receptor	receptor	NOUN
dti-3574	57	21	signalling	signal	VERB
dti-3574	57	22	pathways	pathway	NOUN
dti-3574	57	23	androgen	androgen	NOUN
dti-3574	57	24	receptor	receptor	NOUN
dti-3574	57	25	ligand	ligand	NOUN
dti-3574	57	26	binding	bind	VERB
dti-3574	57	27	domain	domain	NOUN
dti-3574	57	28	(	(	PUNCT
dti-3574	57	29	ar	ar	NOUN
dti-3574	57	30	-	-	PUNCT
dti-3574	57	31	lbd	lbd	NOUN
dti-3574	57	32	)	)	PUNCT
dti-3574	57	33	nr_ar_lbd	nr_ar_lbd	X
dti-3574	57	34	inactive	inactive	ADJ
dti-3574	57	35	0.97	0.97	NUM
dti-3574	57	36	tox21	tox21	PROPN
dti-3574	57	37	-	-	PUNCT
dti-3574	57	38	nuclear	nuclear	ADJ
dti-3574	57	39	receptor	receptor	NOUN
dti-3574	57	40	signalling	signal	VERB
dti-3574	57	41	pathways	pathway	NOUN
dti-3574	57	42	aromatase	aromatase	NOUN
dti-3574	57	43	nr_aromatas	nr_aromata	NOUN
dti-3574	57	44	e	e	NOUN
dti-3574	57	45	inactive	inactive	ADJ
dti-3574	57	46	0.91	0.91	NUM
dti-3574	57	47	tox21	tox21	NOUN
dti-3574	57	48	-	-	PUNCT
dti-3574	57	49	nuclear	nuclear	ADJ
dti-3574	57	50	receptor	receptor	NOUN
dti-3574	57	51	signalling	signal	VERB
dti-3574	57	52	pathways	pathway	NOUN
dti-3574	57	53	estrogen	estrogen	NOUN
dti-3574	57	54	receptor	receptor	NOUN
dti-3574	57	55	alpha	alpha	NOUN
dti-3574	57	56	(	(	PUNCT
dti-3574	57	57	er	er	INTJ
dti-3574	57	58	)	)	PUNCT
dti-3574	57	59	nr_er	nr_er	NOUN
dti-3574	57	60	active	active	ADJ
dti-3574	57	61	0.87	0.87	NUM
dti-3574	57	62	tox21	tox21	PROPN
dti-3574	57	63	-	-	PUNCT
dti-3574	57	64	nuclear	nuclear	ADJ
dti-3574	57	65	receptor	receptor	NOUN
dti-3574	57	66	signalling	signal	VERB
dti-3574	57	67	pathways	pathway	NOUN
dti-3574	57	68	estrogen	estrogen	NOUN
dti-3574	57	69	receptor	receptor	NOUN
dti-3574	57	70	ligand	ligand	NOUN
dti-3574	57	71	binding	bind	VERB
dti-3574	57	72	domain	domain	NOUN
dti-3574	57	73	(	(	PUNCT
dti-3574	57	74	er	er	INTJ
dti-3574	57	75	-	-	PUNCT
dti-3574	57	76	lbd	lbd	NOUN
dti-3574	57	77	)	)	PUNCT
dti-3574	57	78	nr_er_lbd	nr_er_lbd	X
dti-3574	57	79	active	active	ADJ
dti-3574	57	80	0.95	0.95	NUM
dti-3574	57	81	tox21	tox21	PROPN
dti-3574	57	82	-	-	PUNCT
dti-3574	57	83	nuclear	nuclear	ADJ
dti-3574	57	84	receptor	receptor	NOUN
dti-3574	57	85	signalling	signal	VERB
dti-3574	57	86	pathways	pathway	NOUN
dti-3574	57	87	peroxisome	peroxisome	NOUN
dti-3574	57	88	proliferator	proliferator	NOUN
dti-3574	57	89	activated	activate	VERB
dti-3574	57	90	receptor	receptor	NOUN
dti-3574	57	91	gamma	gamma	NOUN
dti-3574	57	92	(	(	PUNCT
dti-3574	57	93	ppargamma	ppargamma	PROPN
dti-3574	57	94	)	)	PUNCT
dti-3574	57	95	nr_ppar_ga	nr_ppar_ga	PROPN
dti-3574	57	96	mma	mma	PROPN
dti-3574	57	97	inactive	inactive	ADJ
dti-3574	57	98	0.98	0.98	NUM
dti-3574	57	99	tox21	tox21	PROPN
dti-3574	57	100	-	-	PUNCT
dti-3574	57	101	stress	stress	NOUN
dti-3574	57	102	response	response	NOUN
dti-3574	57	103	pathways	pathway	NOUN
dti-3574	57	104	nuclear	nuclear	ADJ
dti-3574	57	105	factor	factor	NOUN
dti-3574	57	106	(	(	PUNCT
dti-3574	57	107	erythroid	erythroid	ADJ
dti-3574	57	108	-	-	PUNCT
dti-3574	57	109	derived	derive	VERB
dti-3574	57	110	2)-like	2)-like	NUM
dti-3574	57	111	2	2	NUM
dti-3574	57	112	/	/	SYM
dti-3574	57	113	antioxidant	antioxidant	ADJ
dti-3574	57	114	responsive	responsive	ADJ
dti-3574	57	115	element	element	NOUN
dti-3574	57	116	(	(	PUNCT
dti-3574	57	117	nrf2	nrf2	PROPN
dti-3574	57	118	/	/	SYM
dti-3574	57	119	are	be	AUX
dti-3574	57	120	)	)	PUNCT
dti-3574	57	121	sr_are	sr_are	ADJ
dti-3574	57	122	inactive	inactive	ADJ
dti-3574	57	123	0.99	0.99	NUM
dti-3574	57	124	tox21	tox21	NOUN
dti-3574	57	125	-	-	PUNCT
dti-3574	57	126	stress	stress	NOUN
dti-3574	57	127	response	response	NOUN
dti-3574	57	128	pathways	pathway	NOUN
dti-3574	57	129	heat	heat	NOUN
dti-3574	57	130	shock	shock	NOUN
dti-3574	57	131	factor	factor	NOUN
dti-3574	57	132	response	response	NOUN
dti-3574	57	133	element	element	NOUN
dti-3574	57	134	(	(	PUNCT
dti-3574	57	135	hse	hse	PROPN
dti-3574	57	136	)	)	PUNCT
dti-3574	57	137	sr_hse	sr_hse	PROPN
dti-3574	57	138	inactive	inactive	ADJ
dti-3574	57	139	0.99	0.99	NUM
dti-3574	57	140	drug	drug	NOUN
dti-3574	57	141	target	target	NOUN
dti-3574	57	142	insights	insight	NOUN
dti-3574	57	143	2025	2025	NUM
dti-3574	57	144	|	|	ADV
dti-3574	57	145	doi	doi	NOUN
dti-3574	57	146	:	:	PUNCT
dti-3574	57	147	10.33393	10.33393	NUM
dti-3574	57	148	/	/	SYM
dti-3574	57	149	dti.2025.3574	dti.2025.3574	PROPN
dti-3574	57	150	|	|	ADV
dti-3574	57	151	mishra	mishra	PROPN
dti-3574	57	152	et	et	PROPN
dti-3574	57	153	al	al	PROPN
dti-3574	57	154	6	6	NUM
dti-3574	57	155	tox21	tox21	PROPN
dti-3574	57	156	-	-	PUNCT
dti-3574	57	157	stress	stress	NOUN
dti-3574	57	158	response	response	NOUN
dti-3574	57	159	pathways	pathway	NOUN
dti-3574	57	160	mitochondrial	mitochondrial	ADJ
dti-3574	57	161	membrane	membrane	NOUN
dti-3574	57	162	potential	potential	NOUN
dti-3574	57	163	(	(	PUNCT
dti-3574	57	164	mmp	mmp	PROPN
dti-3574	57	165	)	)	PUNCT
dti-3574	57	166	sr_mmp	sr_mmp	PROPN
dti-3574	58	1	active	active	ADJ
dti-3574	58	2	1	1	NUM
dti-3574	58	3	tox21	tox21	PROPN
dti-3574	58	4	-	-	PUNCT
dti-3574	58	5	stress	stress	NOUN
dti-3574	58	6	response	response	NOUN
dti-3574	58	7	pathways	pathway	NOUN
dti-3574	58	8	phosphoprotein	phosphoprotein	NOUN
dti-3574	58	9	(	(	PUNCT
dti-3574	58	10	tumor	tumor	NOUN
dti-3574	58	11	supressor	supressor	NOUN
dti-3574	58	12	)	)	PUNCT
dti-3574	58	13	p53	p53	NOUN
dti-3574	58	14	sr_p53	sr_p53	PROPN
dti-3574	58	15	inactive	inactive	PROPN
dti-3574	58	16	0.97	0.97	NUM
dti-3574	58	17	tox21	tox21	PROPN
dti-3574	58	18	-	-	PUNCT
dti-3574	58	19	stress	stress	NOUN
dti-3574	58	20	response	response	NOUN
dti-3574	58	21	pathways	pathway	NOUN
dti-3574	58	22	atpase	atpase	PROPN
dti-3574	58	23	family	family	PROPN
dti-3574	58	24	aaa	aaa	NOUN
dti-3574	58	25	domaincontaining	domaincontaine	VERB
dti-3574	58	26	protein	protein	NOUN
dti-3574	58	27	5	5	NUM
dti-3574	58	28	(	(	PUNCT
dti-3574	58	29	atad5	atad5	NOUN
dti-3574	58	30	)	)	PUNCT
dti-3574	58	31	sr_atad5	sr_atad5	PROPN
dti-3574	58	32	inactive	inactive	ADJ
dti-3574	58	33	0.99	0.99	NUM
dti-3574	58	34	molecular	molecular	ADJ
dti-3574	58	35	initiating	initiate	VERB
dti-3574	58	36	events	event	NOUN
dti-3574	58	37	thyroid	thyroid	VERB
dti-3574	58	38	hormone	hormone	NOUN
dti-3574	58	39	receptor	receptor	NOUN
dti-3574	58	40	alpha	alpha	NOUN
dti-3574	58	41	(	(	PUNCT
dti-3574	58	42	thrα	thrα	NOUN
dti-3574	58	43	)	)	PUNCT
dti-3574	58	44	mie_thr_alp	mie_thr_alp	NOUN
dti-3574	58	45	ha	ha	INTJ
dti-3574	58	46	inactive	inactive	ADJ
dti-3574	58	47	0.90	0.90	NUM
dti-3574	58	48	molecular	molecular	ADJ
dti-3574	58	49	initiating	initiate	VERB
dti-3574	58	50	events	event	NOUN
dti-3574	58	51	thyroid	thyroid	VERB
dti-3574	58	52	hormone	hormone	NOUN
dti-3574	58	53	receptor	receptor	NOUN
dti-3574	58	54	beta	beta	NOUN
dti-3574	58	55	(	(	PUNCT
dti-3574	58	56	thrβ	thrβ	PROPN
dti-3574	58	57	)	)	PUNCT
dti-3574	58	58	mie_thr_bet	mie_thr_bet	PROPN
dti-3574	58	59	a	a	DET
dti-3574	58	60	inactive	inactive	ADJ
dti-3574	58	61	0.78	0.78	NUM
dti-3574	58	62	molecular	molecular	ADJ
dti-3574	58	63	initiating	initiate	VERB
dti-3574	58	64	events	event	NOUN
dti-3574	58	65	transtyretrin	transtyretrin	NOUN
dti-3574	58	66	(	(	PUNCT
dti-3574	58	67	ttr	ttr	NOUN
dti-3574	58	68	)	)	PUNCT
dti-3574	58	69	mie_ttr	mie_ttr	NOUN
dti-3574	58	70	inactive	inactive	ADJ
dti-3574	58	71	0.97	0.97	NUM
dti-3574	58	72	molecular	molecular	ADJ
dti-3574	58	73	initiating	initiate	VERB
dti-3574	58	74	events	event	NOUN
dti-3574	58	75	ryanodine	ryanodine	NOUN
dti-3574	59	1	receptor	receptor	NOUN
dti-3574	59	2	(	(	PUNCT
dti-3574	59	3	ryr	ryr	NOUN
dti-3574	59	4	)	)	PUNCT
dti-3574	59	5	mie_ryr	mie_ryr	NOUN
dti-3574	59	6	inactive	inactive	ADJ
dti-3574	59	7	0.98	0.98	NUM
dti-3574	59	8	molecular	molecular	ADJ
dti-3574	59	9	initiating	initiate	VERB
dti-3574	59	10	events	event	NOUN
dti-3574	59	11	gaba	gaba	NOUN
dti-3574	59	12	receptor	receptor	NOUN
dti-3574	59	13	(	(	PUNCT
dti-3574	59	14	gabar	gabar	NOUN
dti-3574	59	15	)	)	PUNCT
dti-3574	59	16	mie_gabar	mie_gabar	X
dti-3574	59	17	inactive	inactive	ADJ
dti-3574	59	18	0.96	0.96	NUM
dti-3574	59	19	molecular	molecular	ADJ
dti-3574	59	20	initiating	initiate	VERB
dti-3574	59	21	events	event	NOUN
dti-3574	59	22	glutamate	glutamate	VERB
dti-3574	59	23	n	n	CCONJ
dti-3574	59	24	-	-	PUNCT
dti-3574	59	25	methyl	methyl	NOUN
dti-3574	59	26	-	-	PUNCT
dti-3574	59	27	d	d	NOUN
dti-3574	59	28	-	-	PUNCT
dti-3574	59	29	aspartate	aspartate	ADJ
dti-3574	59	30	receptor	receptor	NOUN
dti-3574	59	31	(	(	PUNCT
dti-3574	59	32	nmdar	nmdar	ADV
dti-3574	59	33	)	)	PUNCT
dti-3574	59	34	mie_nmdar	mie_nmdar	VERB
dti-3574	59	35	inactive	inactive	ADJ
dti-3574	59	36	0.92	0.92	NUM
dti-3574	59	37	molecular	molecular	ADJ
dti-3574	59	38	initiating	initiate	VERB
dti-3574	59	39	events	event	NOUN
dti-3574	59	40	alpha	alpha	NOUN
dti-3574	59	41	-	-	PUNCT
dti-3574	59	42	amino-3	amino-3	ADJ
dti-3574	59	43	-	-	PUNCT
dti-3574	59	44	hydroxy-5	hydroxy-5	NUM
dti-3574	59	45	-	-	PUNCT
dti-3574	59	46	methyl4	methyl4	NOUN
dti-3574	59	47	-	-	PUNCT
dti-3574	59	48	isoxazolepropionate	isoxazolepropionate	NOUN
dti-3574	59	49	receptor	receptor	NOUN
dti-3574	59	50	(	(	PUNCT
dti-3574	59	51	ampar	ampar	NOUN
dti-3574	59	52	)	)	PUNCT
dti-3574	59	53	mie_ampar	mie_ampar	VERB
dti-3574	59	54	inactive	inactive	ADJ
dti-3574	59	55	0.97	0.97	NUM
dti-3574	59	56	molecular	molecular	ADJ
dti-3574	59	57	initiating	initiate	VERB
dti-3574	59	58	events	event	NOUN
dti-3574	59	59	kainate	kainate	NOUN
dti-3574	59	60	receptor	receptor	NOUN
dti-3574	59	61	(	(	PUNCT
dti-3574	59	62	kar	kar	NOUN
dti-3574	59	63	)	)	PUNCT
dti-3574	59	64	mie_kar	mie_kar	NOUN
dti-3574	59	65	inactive	inactive	ADJ
dti-3574	59	66	0.99	0.99	NUM
dti-3574	59	67	molecular	molecular	ADJ
dti-3574	59	68	initiating	initiate	VERB
dti-3574	59	69	events	event	NOUN
dti-3574	59	70	achetylcholinesterase	achetylcholinesterase	NOUN
dti-3574	59	71	(	(	PUNCT
dti-3574	59	72	ache	ache	PROPN
dti-3574	59	73	)	)	PUNCT
dti-3574	59	74	mie_ache	mie_ache	X
dti-3574	59	75	inactive	inactive	ADJ
dti-3574	59	76	0.69	0.69	NUM
dti-3574	59	77	molecular	molecular	ADJ
dti-3574	59	78	initiating	initiate	VERB
dti-3574	59	79	events	event	NOUN
dti-3574	59	80	constitutive	constitutive	ADJ
dti-3574	59	81	androstane	androstane	ADJ
dti-3574	59	82	receptor	receptor	NOUN
dti-3574	59	83	(	(	PUNCT
dti-3574	59	84	car	car	NOUN
dti-3574	59	85	)	)	PUNCT
dti-3574	59	86	mie_car	mie_car	NOUN
dti-3574	59	87	inactive	inactive	ADJ
dti-3574	59	88	0.98	0.98	NUM
dti-3574	59	89	molecular	molecular	ADJ
dti-3574	59	90	initiating	initiate	VERB
dti-3574	59	91	events	event	NOUN
dti-3574	59	92	pregnane	pregnane	ADJ
dti-3574	59	93	x	x	PUNCT
dti-3574	59	94	receptor	receptor	NOUN
dti-3574	59	95	(	(	PUNCT
dti-3574	59	96	pxr	pxr	PROPN
dti-3574	59	97	)	)	PUNCT
dti-3574	59	98	mie_pxr	mie_pxr	ADP
dti-3574	59	99	inactive	inactive	ADJ
dti-3574	59	100	0.92	0.92	NUM
dti-3574	59	101	molecular	molecular	ADJ
dti-3574	59	102	initiating	initiate	VERB
dti-3574	59	103	events	event	NOUN
dti-3574	59	104	nadh	nadh	NOUN
dti-3574	59	105	-	-	PUNCT
dti-3574	59	106	quinone	quinone	NOUN
dti-3574	59	107	oxidoreductase	oxidoreductase	NOUN
dti-3574	59	108	(	(	PUNCT
dti-3574	59	109	nadhox	nadhox	NOUN
dti-3574	59	110	)	)	PUNCT
dti-3574	59	111	mie_nadhox	mie_nadhox	NOUN
dti-3574	59	112	inactive	inactive	ADJ
dti-3574	59	113	0.97	0.97	NUM
dti-3574	59	114	molecular	molecular	ADJ
dti-3574	59	115	initiating	initiate	VERB
dti-3574	59	116	events	event	NOUN
dti-3574	59	117	voltage	voltage	NOUN
dti-3574	59	118	gated	gate	VERB
dti-3574	59	119	sodium	sodium	NOUN
dti-3574	59	120	channel	channel	NOUN
dti-3574	59	121	(	(	PUNCT
dti-3574	59	122	vgsc	vgsc	ADJ
dti-3574	59	123	)	)	PUNCT
dti-3574	59	124	mie_vgsc	mie_vgsc	NOUN
dti-3574	59	125	inactive	inactive	ADJ
dti-3574	59	126	0.95	0.95	NUM
dti-3574	59	127	molecular	molecular	ADJ
dti-3574	59	128	initiating	initiate	VERB
dti-3574	59	129	events	event	NOUN
dti-3574	59	130	na+/isymporter	na+/isymporter	NOUN
dti-3574	59	131	(	(	PUNCT
dti-3574	59	132	nis	nis	NOUN
dti-3574	59	133	)	)	PUNCT
dti-3574	59	134	mie_nis	mie_ni	NOUN
dti-3574	59	135	inactive	inactive	ADJ
dti-3574	59	136	0.98	0.98	NUM
dti-3574	59	137	metabolism	metabolism	NOUN
dti-3574	59	138	cytochrome	cytochrome	NOUN
dti-3574	59	139	cyp1a2	cyp1a2	PROPN
dti-3574	59	140	cyp1a2	cyp1a2	PROPN
dti-3574	59	141	active	active	ADJ
dti-3574	59	142	1	1	NUM
dti-3574	59	143	metabolism	metabolism	NOUN
dti-3574	59	144	cytochrome	cytochrome	NOUN
dti-3574	59	145	cyp2c19	cyp2c19	NOUN
dti-3574	59	146	cyp2c19	cyp2c19	NOUN
dti-3574	59	147	active	active	ADJ
dti-3574	59	148	0.77	0.77	NUM
dti-3574	59	149	drug	drug	NOUN
dti-3574	59	150	target	target	NOUN
dti-3574	59	151	insights	insight	NOUN
dti-3574	59	152	2025	2025	NUM
dti-3574	59	153	|	|	ADV
dti-3574	59	154	doi	doi	NOUN
dti-3574	59	155	:	:	PUNCT
dti-3574	59	156	10.33393	10.33393	NUM
dti-3574	59	157	/	/	SYM
dti-3574	59	158	dti.2025.3574	dti.2025.3574	PROPN
dti-3574	59	159	|	|	ADV
dti-3574	59	160	mishra	mishra	PROPN
dti-3574	59	161	et	et	PROPN
dti-3574	59	162	al	al	PROPN
dti-3574	59	163	7	7	NUM
dti-3574	59	164	metabolism	metabolism	NOUN
dti-3574	59	165	cytochrome	cytochrome	NOUN
dti-3574	59	166	cyp2c9	cyp2c9	NOUN
dti-3574	59	167	cyp2c9	cyp2c9	NOUN
dti-3574	59	168	active	active	ADJ
dti-3574	59	169	0.99	0.99	NUM
dti-3574	59	170	metabolism	metabolism	NOUN
dti-3574	59	171	cytochrome	cytochrome	NOUN
dti-3574	59	172	cyp2d6	cyp2d6	NOUN
dti-3574	59	173	cyp2d6	cyp2d6	NOUN
dti-3574	59	174	inactive	inactive	ADJ
dti-3574	59	175	0.85	0.85	NUM
dti-3574	59	176	metabolism	metabolism	NOUN
dti-3574	59	177	cytochrome	cytochrome	NOUN
dti-3574	59	178	cyp3a4	cyp3a4	PROPN
dti-3574	59	179	cyp3a4	cyp3a4	PROPN
dti-3574	59	180	inactive	inactive	ADJ
dti-3574	59	181	0.79	0.79	NUM
dti-3574	59	182	metabolism	metabolism	NOUN
dti-3574	59	183	cytochrome	cytochrome	NOUN
dti-3574	59	184	cyp2e1	cyp2e1	ADJ
dti-3574	59	185	cyp2e1	cyp2e1	ADJ
dti-3574	59	186	inactive	inactive	ADJ
dti-3574	59	187	1	1	NUM
dti-3574	59	188	drug	drug	NOUN
dti-3574	59	189	target	target	NOUN
dti-3574	59	190	insights	insight	NOUN
dti-3574	59	191	2025	2025	NUM
dti-3574	59	192	|	|	ADV
dti-3574	59	193	doi	doi	NOUN
dti-3574	59	194	:	:	PUNCT
dti-3574	59	195	10.33393	10.33393	NUM
dti-3574	59	196	/	/	SYM
dti-3574	59	197	dti.2025.3574	dti.2025.3574	PROPN
dti-3574	59	198	|	|	ADV
dti-3574	59	199	mishra	mishra	PROPN
dti-3574	59	200	et	et	PROPN
dti-3574	59	201	al	al	PROPN
dti-3574	59	202	8	8	NUM
dti-3574	59	203	table	table	NOUN
dti-3574	59	204	s	s	NOUN
dti-3574	59	205	-	-	PUNCT
dti-3574	59	206	vi	vi	NOUN
dti-3574	59	207	.	.	NOUN
dti-3574	59	208	osiris	osiris	PROPN
dti-3574	59	209	and	and	CCONJ
dti-3574	59	210	molinspiration	molinspiration	NOUN
dti-3574	59	211	calculation	calculation	NOUN
dti-3574	59	212	of	of	ADP
dti-3574	59	213	apigenin	apigenin	PROPN
dti-3574	59	214	,	,	PUNCT
dti-3574	59	215	fisetin	fisetin	ADJ
dti-3574	59	216	acid	acid	NOUN
dti-3574	59	217	,	,	PUNCT
dti-3574	59	218	cosmosiin	cosmosiin	NOUN
dti-3574	59	219	and	and	CCONJ
dti-3574	59	220	baicalein	baicalein	PROPN
dti-3574	59	221	.	.	PUNCT
dti-3574	60	1	compound	compound	NOUN
dti-3574	60	2	name	name	NOUN
dti-3574	60	3	2d/3d	2d/3d	NUM
dti-3574	60	4	molecular	molecular	ADJ
dti-3574	60	5	structure	structure	NOUN
dti-3574	60	6	drug	drug	NOUN
dti-3574	60	7	score	score	NOUN
dti-3574	60	8	(	(	PUNCT
dti-3574	60	9	ds	ds	ADJ
dti-3574	60	10	)	)	PUNCT
dti-3574	60	11	apigenin	apigenin	PROPN
dti-3574	60	12	milogp	milogp	NOUN
dti-3574	60	13	2.46	2.46	NUM
dti-3574	60	14	tpsa	tpsa	NOUN
dti-3574	60	15	90.89	90.89	NUM
dti-3574	60	16	natoms	natom	NOUN
dti-3574	60	17	20	20	NUM
dti-3574	60	18	mw	mw	NOUN
dti-3574	60	19	270.24	270.24	NUM
dti-3574	60	20	non	non	X
dti-3574	60	21	5	5	NUM
dti-3574	60	22	nohnh	nohnh	NOUN
dti-3574	60	23	3	3	NUM
dti-3574	60	24	nviolations	nviolation	NOUN
dti-3574	60	25	0	0	NUM
dti-3574	60	26	nrotb	nrotb	NUM
dti-3574	60	27	1	1	NUM
dti-3574	60	28	volume	volume	NOUN
dti-3574	60	29	224.05	224.05	NUM
dti-3574	60	30	fisetin	fisetin	NOUN
dti-3574	60	31	acid	acid	NOUN
dti-3574	60	32	milogp	milogp	NOUN
dti-3574	60	33	1.97	1.97	NUM
dti-3574	60	34	tpsa	tpsa	NOUN
dti-3574	60	35	111.12	111.12	NUM
dti-3574	60	36	natoms	natom	NOUN
dti-3574	60	37	21	21	NUM
dti-3574	60	38	mw	mw	NOUN
dti-3574	60	39	286.24	286.24	NUM
dti-3574	60	40	non	non	X
dti-3574	60	41	6	6	NUM
dti-3574	60	42	nohnh	nohnh	NOUN
dti-3574	60	43	4	4	NUM
dti-3574	60	44	nviolations	nviolation	NOUN
dti-3574	60	45	0	0	SYM
dti-3574	60	46	nrotb	nrotb	NUM
dti-3574	60	47	1	1	NUM
dti-3574	60	48	volume	volume	NOUN
dti-3574	60	49	232.07	232.07	NUM
dti-3574	60	50	drug	drug	NOUN
dti-3574	60	51	target	target	NOUN
dti-3574	60	52	insights	insight	NOUN
dti-3574	60	53	2025	2025	NUM
dti-3574	60	54	|	|	ADV
dti-3574	60	55	doi	doi	NOUN
dti-3574	60	56	:	:	PUNCT
dti-3574	60	57	10.33393	10.33393	NUM
dti-3574	60	58	/	/	SYM
dti-3574	60	59	dti.2025.3574	dti.2025.3574	PROPN
dti-3574	60	60	|	|	ADV
dti-3574	60	61	mishra	mishra	PROPN
dti-3574	60	62	et	et	PROPN
dti-3574	60	63	al	al	PROPN
dti-3574	60	64	9	9	NUM
dti-3574	60	65	cosmosiin	cosmosiin	NOUN
dti-3574	60	66	milogp	milogp	NOUN
dti-3574	60	67	0.39	0.39	NUM
dti-3574	60	68	tpsa	tpsa	PROPN
dti-3574	60	69	190.28	190.28	NUM
dti-3574	60	70	natoms	natom	NOUN
dti-3574	60	71	32	32	NUM
dti-3574	60	72	mw	mw	PROPN
dti-3574	60	73	448.38	448.38	NUM
dti-3574	60	74	non	non	ADJ
dti-3574	60	75	11	11	NUM
dti-3574	60	76	nohnh	nohnh	NOUN
dti-3574	60	77	7	7	NUM
dti-3574	60	78	nviolations	nviolation	NOUN
dti-3574	61	1	2	2	NUM
dti-3574	61	2	nrotb	nrotb	NUM
dti-3574	61	3	4	4	NUM
dti-3574	61	4	volume	volume	NOUN
dti-3574	61	5	364.19	364.19	NUM
dti-3574	61	6	baicalein	baicalein	NOUN
dti-3574	61	7	milogp	milogp	VERB
dti-3574	61	8	2.68	2.68	NUM
dti-3574	61	9	tpsa	tpsa	NOUN
dti-3574	61	10	90.89	90.89	NUM
dti-3574	61	11	natoms	natom	NOUN
dti-3574	61	12	20	20	NUM
dti-3574	61	13	mw	mw	NOUN
dti-3574	61	14	270.24	270.24	NUM
dti-3574	61	15	non	non	X
dti-3574	61	16	5	5	NUM
dti-3574	61	17	nohnh	nohnh	NOUN
dti-3574	61	18	3	3	NUM
dti-3574	61	19	nviolations	nviolation	NOUN
dti-3574	61	20	0	0	NUM
dti-3574	61	21	nrotb	nrotb	NUM
dti-3574	61	22	1	1	NUM
dti-3574	61	23	volume	volume	NOUN
dti-3574	61	24	224.05	224.05	NUM
dti-3574	61	25	drug	drug	NOUN
dti-3574	61	26	target	target	NOUN
dti-3574	61	27	insights	insight	NOUN
dti-3574	61	28	2025	2025	NUM
dti-3574	61	29	|	|	ADV
dti-3574	61	30	doi	doi	NOUN
dti-3574	61	31	:	:	PUNCT
dti-3574	61	32	10.33393	10.33393	NUM
dti-3574	61	33	/	/	SYM
dti-3574	61	34	dti.2025.3574	dti.2025.3574	PROPN
dti-3574	61	35	|	|	ADV
dti-3574	61	36	mishra	mishra	PROPN
dti-3574	61	37	et	et	PROPN
dti-3574	61	38	al	al	PROPN
dti-3574	61	39	10	10	NUM
dti-3574	61	40	supplementary	supplementary	ADJ
dti-3574	61	41	figures	figure	NOUN
dti-3574	61	42	fig	fig	NOUN
dti-3574	61	43	.	.	PUNCT
dti-3574	62	1	s1	s1	NOUN
dti-3574	62	2	.	.	PUNCT
dti-3574	63	1	organigram	organigram	PROPN
dti-3574	63	2	of	of	ADP
dti-3574	63	3	pom	pom	PROPN
dti-3574	63	4	theory	theory	NOUN
dti-3574	63	5	,	,	PUNCT
dti-3574	63	6	serving	serve	VERB
dti-3574	63	7	as	as	ADP
dti-3574	63	8	a	a	DET
dti-3574	63	9	guide	guide	NOUN
dti-3574	63	10	to	to	PART
dti-3574	63	11	identify	identify	VERB
dti-3574	63	12	various	various	ADJ
dti-3574	63	13	pharmacophore	pharmacophore	NOUN
dti-3574	63	14	sites	site	NOUN
dti-3574	63	15	of	of	ADP
dti-3574	63	16	bioactive	bioactive	ADJ
dti-3574	63	17	molecules	molecule	NOUN
dti-3574	63	18	(	(	PUNCT
dti-3574	63	19	46,47	46,47	NUM
dti-3574	63	20	)	)	PUNCT
dti-3574	63	21	.	.	PUNCT
dti-3574	64	1	drug	drug	NOUN
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dti-3574	64	5	|	|	ADV
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dti-3574	64	7	:	:	PUNCT
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dti-3574	64	21	.	.	PUNCT
dti-3574	65	1	s2	s2	PROPN
dti-3574	65	2	.	.	PUNCT
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dti-3574	66	4	baicalein	baicalein	NOUN
dti-3574	66	5	(	(	PUNCT
dti-3574	66	6	a	a	NOUN
dti-3574	66	7	)	)	PUNCT
dti-3574	66	8	,	,	PUNCT
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dti-3574	66	10	-	-	NOUN
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dti-3574	66	12	(	(	PUNCT
dti-3574	66	13	b	b	NOUN
dti-3574	66	14	)	)	PUNCT
dti-3574	66	15	,	,	PUNCT
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dti-3574	66	20	yl-4	yl-4	NOUN
dti-3574	66	21	-	-	PUNCT
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dti-3574	66	23	-	-	PUNCT
dti-3574	66	24	yl-1h	yl-1h	NOUN
dti-3574	66	25	-	-	PUNCT
dti-3574	66	26	imidazol-2	imidazol-2	NUM
dti-3574	66	27	-	-	PUNCT
dti-3574	66	28	yl)benzamide	yl)benzamide	NOUN
dti-3574	66	29	(	(	PUNCT
dti-3574	66	30	c	c	NOUN
dti-3574	66	31	)	)	PUNCT
dti-3574	66	32	and	and	CCONJ
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dti-3574	66	34	-	-	PUNCT
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dti-3574	66	36	-	-	PUNCT
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dti-3574	66	38	-	-	PUNCT
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dti-3574	66	40	-	-	PUNCT
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dti-3574	66	42	-	-	PUNCT
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dti-3574	66	44	(	(	PUNCT
dti-3574	66	45	d	d	NOUN
dti-3574	66	46	)	)	PUNCT
dti-3574	66	47	.	.	PUNCT
dti-3574	67	1	fig	fig	NOUN
dti-3574	67	2	.	.	PUNCT
dti-3574	68	1	s3	s3	PROPN
dti-3574	68	2	.	.	PUNCT
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dti-3574	69	2	plots	plot	NOUN
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dti-3574	69	4	via	via	ADP
dti-3574	69	5	procheck	procheck	NOUN
dti-3574	69	6	for	for	ADP
dti-3574	69	7	1vjy	1vjy	NUM
dti-3574	69	8	,	,	PUNCT
dti-3574	69	9	3tzm	3tzm	PROPN
dti-3574	69	10	(	(	PUNCT
dti-3574	69	11	b	b	NOUN
dti-3574	69	12	)	)	PUNCT
dti-3574	69	13	,	,	PUNCT
dti-3574	69	14	and	and	CCONJ
dti-3574	69	15	7dv6	7dv6	NUM
dti-3574	69	16	demonstrate	demonstrate	VERB
dti-3574	69	17	that	that	SCONJ
dti-3574	69	18	the	the	DET
dti-3574	69	19	target	target	NOUN
dti-3574	69	20	protein	protein	NOUN
dti-3574	69	21	’s	’s	PART
dti-3574	69	22	geometry	geometry	NOUN
dti-3574	69	23	matches	match	VERB
dti-3574	69	24	the	the	DET
dti-3574	69	25	most	most	ADV
dti-3574	69	26	likely	likely	ADJ
dti-3574	69	27	shape	shape	NOUN
dti-3574	69	28	based	base	VERB
dti-3574	69	29	on	on	ADP
dti-3574	69	30	the	the	DET
dti-3574	69	31	torsional	torsional	ADJ
dti-3574	69	32	angles	angle	NOUN
dti-3574	69	33	(	(	PUNCT
dti-3574	69	34	ϕ	ϕ	NOUN
dti-3574	69	35	and	and	CCONJ
dti-3574	69	36	ψ	ψ	NOUN
dti-3574	69	37	)	)	PUNCT
dti-3574	69	38	of	of	ADP
dti-3574	69	39	its	its	PRON
dti-3574	69	40	amino	amino	NOUN
dti-3574	69	41	acid	acid	NOUN
dti-3574	69	42	residues	residue	NOUN
dti-3574	69	43	.	.	PUNCT
dti-3574	70	1	procheck	procheck	NOUN
dti-3574	70	2	displays	display	VERB
dti-3574	70	3	the	the	DET
dti-3574	70	4	residues	residue	NOUN
dti-3574	70	5	in	in	ADP
dti-3574	70	6	most	most	ADV
dti-3574	70	7	favoured	favour	VERB
dti-3574	70	8	(	(	PUNCT
dti-3574	70	9	red	red	ADJ
dti-3574	70	10	)	)	PUNCT
dti-3574	70	11	,	,	PUNCT
dti-3574	70	12	additionally	additionally	ADV
dti-3574	70	13	allowed	allow	VERB
dti-3574	70	14	(	(	PUNCT
dti-3574	70	15	light	light	ADJ
dti-3574	70	16	brown	brown	NOUN
dti-3574	70	17	)	)	PUNCT
dti-3574	70	18	,	,	PUNCT
dti-3574	70	19	generously	generously	ADV
dti-3574	70	20	allowed	allow	VERB
dti-3574	70	21	(	(	PUNCT
dti-3574	70	22	yellow	yellow	ADJ
dti-3574	70	23	)	)	PUNCT
dti-3574	70	24	and	and	CCONJ
dti-3574	70	25	disallowed	disallow	VERB
dti-3574	70	26	regions	region	NOUN
dti-3574	70	27	(	(	PUNCT
dti-3574	70	28	pale	pale	ADJ
dti-3574	70	29	yellow	yellow	NOUN
dti-3574	70	30	)	)	PUNCT
dti-3574	70	31	.	.	PUNCT
dti-3574	71	1	drug	drug	NOUN
dti-3574	71	2	target	target	NOUN
dti-3574	71	3	insights	insight	NOUN
dti-3574	71	4	2025	2025	NUM
dti-3574	71	5	|	|	ADV
dti-3574	71	6	doi	doi	NOUN
dti-3574	71	7	:	:	PUNCT
dti-3574	71	8	10.33393	10.33393	NUM
dti-3574	71	9	/	/	SYM
dti-3574	71	10	dti.2025.3574	dti.2025.3574	PROPN
dti-3574	71	11	|	|	ADV
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dti-3574	71	14	al	al	PROPN
dti-3574	71	15	12	12	NUM
dti-3574	71	16	fig	fig	NOUN
dti-3574	71	17	.	.	PUNCT
dti-3574	72	1	s4	s4	PROPN
dti-3574	72	2	.	.	PUNCT
dti-3574	73	1	analysis	analysis	NOUN
dti-3574	73	2	of	of	ADP
dti-3574	73	3	hydropathy	hydropathy	ADJ
dti-3574	73	4	demonstrating	demonstrate	VERB
dti-3574	73	5	the	the	DET
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dti-3574	73	7	of	of	ADP
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dti-3574	73	9	and	and	CCONJ
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dti-3574	73	13	the	the	DET
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dti-3574	73	15	of	of	ADP
dti-3574	73	16	amino	amino	ADJ
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dti-3574	73	18	,	,	PUNCT
dti-3574	73	19	(	(	PUNCT
dti-3574	73	20	a	a	X
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dti-3574	73	23	,	,	PUNCT
dti-3574	73	24	(	(	PUNCT
dti-3574	73	25	b	b	X
dti-3574	73	26	):	):	PUNCT
dti-3574	73	27	3tzm	3tzm	NOUN
dti-3574	73	28	,	,	PUNCT
dti-3574	73	29	and	and	CCONJ
dti-3574	73	30	(	(	PUNCT
dti-3574	73	31	c	c	NOUN
dti-3574	73	32	):	):	PUNCT
dti-3574	73	33	7dv6	7dv6	NUM
dti-3574	73	34	.	.	PUNCT
dti-3574	74	1	drug	drug	NOUN
dti-3574	74	2	target	target	NOUN
dti-3574	74	3	insights	insight	NOUN
dti-3574	74	4	2025	2025	NUM
dti-3574	74	5	|	|	ADV
dti-3574	74	6	doi	doi	NOUN
dti-3574	74	7	:	:	PUNCT
dti-3574	74	8	10.33393	10.33393	NUM
dti-3574	74	9	/	/	SYM
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dti-3574	74	11	|	|	ADV
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dti-3574	74	16	fig	fig	NOUN
dti-3574	74	17	.	.	PUNCT
dti-3574	75	1	s5	s5	PROPN
dti-3574	75	2	.	.	PUNCT
dti-3574	76	1	bioavailability	bioavailability	NOUN
dti-3574	76	2	radar	radar	NOUN
dti-3574	76	3	plots	plot	NOUN
dti-3574	76	4	of	of	ADP
dti-3574	76	5	baicalein	baicalein	PROPN
dti-3574	76	6	.	.	PUNCT
dti-3574	77	1	the	the	DET
dti-3574	77	2	colour	colour	NOUN
dti-3574	77	3	zone	zone	NOUN
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dti-3574	77	5	the	the	DET
dti-3574	77	6	suitable	suitable	ADJ
dti-3574	77	7	physicochemical	physicochemical	ADJ
dti-3574	77	8	space	space	NOUN
dti-3574	77	9	for	for	ADP
dti-3574	77	10	oral	oral	ADJ
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dti-3574	77	12	.	.	PUNCT
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dti-3574	78	2	=	=	SYM
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dti-3574	78	4	(	(	PUNCT
dti-3574	78	5	−0.7	−0.7	NOUN
dti-3574	78	6	<	<	X
dti-3574	78	7	xlogp3	xlogp3	X
dti-3574	78	8	<	<	X
dti-3574	78	9	+5.0	+5.0	NUM
dti-3574	78	10	and	and	CCONJ
dti-3574	78	11	+3.0	+3.0	NUM
dti-3574	78	12	)	)	PUNCT
dti-3574	78	13	,	,	PUNCT
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dti-3574	78	15	:	:	PUNCT
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dti-3574	78	17	<	<	X
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dti-3574	78	19	<	<	X
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dti-3574	78	24	,	,	PUNCT
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dti-3574	78	26	=	=	NOUN
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dti-3574	78	28	(	(	PUNCT
dti-3574	78	29	20	20	NUM
dti-3574	78	30	å2	å2	PROPN
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dti-3574	78	33	<	<	X
dti-3574	78	34	130	130	NUM
dti-3574	78	35	å2	å2	NOUN
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dti-3574	78	37	,	,	PUNCT
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dti-3574	78	39	=	=	PUNCT
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dti-3574	79	2	(	(	PUNCT
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dti-3574	79	7	<	<	X
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dti-3574	79	9	s	s	X
dti-3574	79	10	(	(	PUNCT
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dti-3574	79	12	)	)	PUNCT
dti-3574	79	13	<	<	X
dti-3574	79	14	0	0	NUM
dti-3574	79	15	)	)	PUNCT
dti-3574	79	16	,	,	PUNCT
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dti-3574	79	18	=	=	SYM
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dti-3574	79	25	<	<	X
dti-3574	79	26	1	1	NUM
dti-3574	79	27	)	)	PUNCT
dti-3574	79	28	,	,	PUNCT
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dti-3574	79	30	=	=	SYM
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dti-3574	79	32	(	(	PUNCT
dti-3574	79	33	0	0	PUNCT
dti-3574	79	34	<	<	X
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dti-3574	79	39	<	<	X
dti-3574	79	40	9	9	NUM
dti-3574	79	41	)	)	PUNCT
dti-3574	79	42	.	.	PUNCT
dti-3574	80	1	drug	drug	NOUN
dti-3574	80	2	target	target	NOUN
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dti-3574	80	5	|	|	ADV
dti-3574	80	6	doi	doi	NOUN
dti-3574	80	7	:	:	PUNCT
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dti-3574	80	9	/	/	SYM
dti-3574	80	10	dti.2025.3574	dti.2025.3574	PROPN
dti-3574	80	11	|	|	ADV
dti-3574	80	12	mishra	mishra	PROPN
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dti-3574	80	16	fig	fig	NOUN
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dti-3574	81	2	.	.	PUNCT
dti-3574	82	1	boiled	boil	VERB
dti-3574	82	2	-	-	PUNCT
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dti-3574	82	4	plot	plot	NOUN
dti-3574	82	5	between	between	ADP
dti-3574	82	6	lipophilicity	lipophilicity	NOUN
dti-3574	82	7	(	(	PUNCT
dti-3574	82	8	wlogp	wlogp	NOUN
dti-3574	82	9	)	)	PUNCT
dti-3574	82	10	and	and	CCONJ
dti-3574	82	11	polarity	polarity	NOUN
dti-3574	82	12	(	(	PUNCT
dti-3574	82	13	tpsa	tpsa	PROPN
dti-3574	82	14	)	)	PUNCT
dti-3574	82	15	showing	show	VERB
dti-3574	82	16	baicalein	baicalein	NOUN
dti-3574	82	17	is	be	AUX
dti-3574	82	18	not	not	PART
dti-3574	82	19	able	able	ADJ
dti-3574	82	20	to	to	PART
dti-3574	82	21	permeate	permeate	VERB
dti-3574	82	22	blood	blood	NOUN
dti-3574	82	23	–	–	PUNCT
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dti-3574	82	25	barrier	barrier	NOUN
dti-3574	82	26	(	(	PUNCT
dti-3574	82	27	bbb	bbb	NOUN
dti-3574	82	28	)	)	PUNCT
dti-3574	82	29	but	but	CCONJ
dti-3574	82	30	passive	passive	ADJ
dti-3574	82	31	absorption	absorption	NOUN
dti-3574	82	32	by	by	ADP
dti-3574	82	33	the	the	DET
dti-3574	82	34	gastrointestinal	gastrointestinal	ADJ
dti-3574	82	35	tract	tract	NOUN
dti-3574	82	36	is	be	AUX
dti-3574	82	37	possible	possible	ADJ
dti-3574	82	38	.	.	PUNCT
dti-3574	83	1	fig	fig	NOUN
dti-3574	83	2	.	.	PUNCT
dti-3574	84	1	s7	s7	NOUN
dti-3574	84	2	.	.	PUNCT
dti-3574	85	1	top	top	ADJ
dti-3574	85	2	15	15	NUM
dti-3574	85	3	targets	target	NOUN
dti-3574	85	4	predicted	predict	VERB
dti-3574	85	5	for	for	ADP
dti-3574	85	6	baicalein	baicalein	PROPN
dti-3574	85	7	.	.	PUNCT
dti-3574	86	1	baicalein	baicalein	PROPN
dti-3574	86	2	drug	drug	NOUN
dti-3574	86	3	target	target	NOUN
dti-3574	86	4	insights	insight	NOUN
dti-3574	86	5	2025	2025	NUM
dti-3574	86	6	|	|	ADV
dti-3574	86	7	doi	doi	NOUN
dti-3574	86	8	:	:	PUNCT
dti-3574	86	9	10.33393	10.33393	NUM
dti-3574	86	10	/	/	SYM
dti-3574	86	11	dti.2025.3574	dti.2025.3574	PROPN
dti-3574	86	12	|	|	ADV
dti-3574	86	13	mishra	mishra	PROPN
dti-3574	86	14	et	et	PROPN
dti-3574	86	15	al	al	PROPN
dti-3574	86	16	15	15	NUM
dti-3574	86	17	fig	fig	NOUN
dti-3574	86	18	.	.	PUNCT
dti-3574	87	1	s8	s8	PROPN
dti-3574	87	2	.	.	PUNCT
dti-3574	88	1	oral	oral	ADJ
dti-3574	88	2	toxicity	toxicity	NOUN
dti-3574	88	3	model	model	NOUN
dti-3574	88	4	report	report	NOUN
dti-3574	88	5	of	of	ADP
dti-3574	88	6	baicalein	baicalein	PROPN
dti-3574	88	7	.	.	PUNCT
dti-3574	89	1	apigenin	apigenin	PROPN
dti-3574	89	2	cosmosin	cosmosin	PROPN
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dti-3574	89	4	acid	acid	PROPN
dti-3574	89	5	baicalein	baicalein	PROPN
dti-3574	89	6	fig	fig	NOUN
dti-3574	89	7	.	.	PUNCT
dti-3574	90	1	s9	s9	NOUN
dti-3574	90	2	.	.	PUNCT
dti-3574	91	1	atomic	atomic	ADJ
dti-3574	91	2	charge	charge	NOUN
dti-3574	91	3	of	of	ADP
dti-3574	91	4	the	the	DET
dti-3574	91	5	compounds	compound	NOUN
dti-3574	91	6	.	.	PUNCT