E- Global Congress Hosted online from Dubai, U. A. E., E - Conference. Date: 30th May 2025 Website: https://eglobalcongress.com/index.php/egc ISSN (E): 2836-3612 113 | P a g e RETROSPECTIVE ANALYSIS OF BRUCELLOSIS AMONG REGIONS AMONG BLOOD DONORS Bobojonova Sh.D.1, Saidov A.B.2, Samatova L.D.1 Tashkent Medical Academy1 Republican blood transfusion center2 Introduction Continuous information and up-to-date information on infectious diseases that can be transmitted through blood transfusions are transmitted through blood transfusions it is necessary to report adverse events that are a component of disease control. [1,3]. Although the risk of transmission of blood transfusion infections is lower than ever today, in the delivery of safe blood products, it remains under contamination with known and not yet identified pathogens (or infections). Only improving and implementing donor selection, sensitive screening tests, and effective inactivation practices can ensure that transfusion-transmitted infections eliminate or reduce the risk of transmission in the absence.[1]. Since the 1950s, it has been known about the risk of contracting brucellosis with blood transfusions [2,3]. Brucellosis is a zoonotic infectious and allergic disease, prone to chronic conditions, accompanied by systemic major damage to the musculoskeletal system, cardiovascular, nervous and genital organs. Brucellosis is widespread in more than 170 countries and regions of the world. [1,2] Aim. Conducting a comparative retrospective analysis of the detection of a brucellosis infection in the donor blood. Research methods and materials. The Republican Center for blood transfusion of the Republic of Uzbekistan in 2013-2023 a retrospective analysis based on statistical documents on the registration of cases of detection of brucellosis among blood donors. https://eglobalcongress.com/index.php/egc E- Global Congress Hosted online from Dubai, U. A. E., E - Conference. Date: 30th May 2025 Website: https://eglobalcongress.com/index.php/egc ISSN (E): 2836-3612 114 | P a g e Results In our study, on the basis of a retrospective analysis on the period 2013-2020, analysis were carried out among donors who applied in the cross section of Regions. (number) (1-diagram) 1-diagram Our study showed that between 2013 and 2020, the most analysis with the number of analyzes in the blood of donors made up the results of the Republic of Karakolpokistan and the Fergana region, while the lowest analysis made up the results of the Syrdarya and Jizzakh regions. (%) (2- diagram) 2-diagram 99,545 68,273 58,687 47,013 68,560 31,179 28,959 67,618 68,560 78,279 91,626 46,119 NUMBER OF ANALAYZES 2013-2020 YY number of analayzes 2013-2020 yy 0.24 0.03 0.19 0.1 0.52 0.61 0.06 1.38 0.95 0.6 0.47 0.08 0 0.2 0.4 0.6 0.8 1 1.2 1.4 1.6 detection % 2013-2020 yy https://eglobalcongress.com/index.php/egc E- Global Congress Hosted online from Dubai, U. A. E., E - Conference. Date: 30th May 2025 Website: https://eglobalcongress.com/index.php/egc ISSN (E): 2836-3612 115 | P a g e Analysis showed that between 2013 and 2020, the highest detection results of brucellosis infection in donor blood with a positive result were in the regions of Kashkadarya and Surkhandarya, the results of the lowest detection were established by the Khorezm and Syrdarya regions. In our study, the analysis carried out between 2021 and 2023 on the basis of retrospective analysis among donors who applied in the cross section of regions (number) (3-diagram) 3-diagram Observations showed these figures, in the highest result among donors in 2021-2023 was 104,400 analysis of the Samarkand region, during this period, the sleeve showed low indicators Jizzakh region 21736 number of analyzes. Brucellosis infection detection indicator among donors who applied in provincial cross section based on retrospective reviews between 2021 and 2023. (%) (4-diagram) 75358 46495 41917 30077 104400 21736 23117 45332 43395 46113 60984 33984 0 20000 40000 60000 80000 100000 120000 Number of analyzes 2021-2023 yy Number of analyzes https://eglobalcongress.com/index.php/egc E- Global Congress Hosted online from Dubai, U. A. E., E - Conference. Date: 30th May 2025 Website: https://eglobalcongress.com/index.php/egc ISSN (E): 2836-3612 116 | P a g e 4-diagram The analysis showed that between 2021 and 2023, the results of the highest detection of brucellosis infection in the blood of donors with a positive result were established by the regions of Jizzakh and Surkhandarya, the results of the lowest detection were established by the Republic of Karakolpokistan, Khorezm and Syrdarya regions. Conclusion: From the study, it can be concluded that between 2013 and 2020, the most highest positive result for brucellosis in the blood of donors was the regions of Surkhandarya and Kashkadarya, while in 2021-2023, Jizzakh and Surkhandarya region showed the most highest positive results. References: 1. Жибурт Е. Б., Мадзаев С. Р., Кузьмин Н. С., Вергопуло А. А. Гемотрансмиссивные инфекции у населения и доноров крови// Вестник Национального медико-хирургического центра им. Н. И. Пирогова.- 2016.- Т.11, № 1.- С.88–90/ 0.09 0.… 0.… 0.74 0.7 7 3.53 0.32 1.19 3.… 1.17 0.19 0.74 0 0.5 1 1.5 2 2.5 3 3.5 4 Detection % 2021-2023 yy Detection % https://eglobalcongress.com/index.php/egc E- Global Congress Hosted online from Dubai, U. A. E., E - Conference. Date: 30th May 2025 Website: https://eglobalcongress.com/index.php/egc ISSN (E): 2836-3612 117 | P a g e 2. Литусов Н. Возбудители бруцеллеза ,иллюстрированное учебное пособие. 2012 й.-С 5-10. 3.М. Н. Губанова, Т. Г. Копченко, О. М. Резникова, С. Р. Мадзаев, Е. Б. Жибурт. Бруцеллез: обследование доноров крови Ставропольского края. Трансфузиология № 3 (том 18) / 2017- С 37-40. https://eglobalcongress.com/index.php/egc