id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
ecletica-1329	Erazua, Ehimen Annastasia; Oyebamiji, Abel Kolawole; Akintelu, Sunday Adewale; Adewole, Pelumi Daniel; Adelakun, Adedayo; Adeleke, Babatunde Benjamin	Quantitative Structure-Activity relationship, Molecular Docking and ADMET Screening of Tetrahydroquinoline Derivatives as Anti-Small Cell Lung Cancer Agents	2023	17	.pdf	application/pdf	8598	498	52	Therefore, this research was aimed at identifying the descriptors that are responsible for anti-EGFR activities thereby downregulating human lung cancer and developing valid quantitative structural relationship activity (QSAR) model using the obtained descriptors as well as observing the nonbonding interactions between the selected phytochemicals (synthesized by Fathy et al., 2020) and EGFR (PDB ID: 4LRM) 2. Methodology 2.1 Quantum Chemical Study For this study, a set of 14 tetrahydroquinoline derivatives obtained from Fathy et al. (2020) as potential anti-EGFR agents with inhibitory activities (IC50) in μmol L–1 (Table 1) was investigated.	cache/ecletica-1329.pdf	txt/ecletica-1329.txt