id	sid	tid	token	lemma	pos
ecletica-1322	1	1	original	original	ADJ
ecletica-1322	1	2	article	article	NOUN
ecletica-1322	1	3	revista.iq.unesp.br	revista.iq.unesp.br	PROPN
ecletica-1322	1	4	|	|	ADJ
ecletica-1322	1	5	vol	vol	NOUN
ecletica-1322	1	6	.	.	PUNCT
ecletica-1322	2	1	47	47	NUM
ecletica-1322	3	1	|	|	ADV
ecletica-1322	3	2	n.	n.	NOUN
ecletica-1322	3	3	4	4	NUM
ecletica-1322	4	1	|	|	ADV
ecletica-1322	4	2	2022	2022	NUM
ecletica-1322	4	3	|	|	ADV
ecletica-1322	4	4	27	27	NUM
ecletica-1322	4	5	eclética	eclética	PROPN
ecletica-1322	4	6	química	química	PROPN
ecletica-1322	4	7	journal	journal	PROPN
ecletica-1322	4	8	,	,	PUNCT
ecletica-1322	4	9	vol	vol	NOUN
ecletica-1322	4	10	.	.	PROPN
ecletica-1322	5	1	47	47	NUM
ecletica-1322	5	2	,	,	PUNCT
ecletica-1322	5	3	n.	n.	NOUN
ecletica-1322	5	4	4	4	NUM
ecletica-1322	5	5	,	,	PUNCT
ecletica-1322	5	6	2022	2022	NUM
ecletica-1322	5	7	,	,	PUNCT
ecletica-1322	5	8	27	27	NUM
ecletica-1322	5	9	-	-	SYM
ecletica-1322	5	10	36	36	NUM
ecletica-1322	5	11	issn	issn	NOUN
ecletica-1322	5	12	:	:	PUNCT
ecletica-1322	5	13	1678	1678	NUM
ecletica-1322	5	14	-	-	SYM
ecletica-1322	5	15	4618	4618	NUM
ecletica-1322	5	16	doi	doi	NOUN
ecletica-1322	5	17	:	:	PUNCT
ecletica-1322	5	18	10.26850/1678	10.26850/1678	NUM
ecletica-1322	5	19	-	-	SYM
ecletica-1322	5	20	4618eqj.v47.4.2022.p27	4618eqj.v47.4.2022.p27	NUM
ecletica-1322	5	21	-	-	PUNCT
ecletica-1322	5	22	36	36	NUM
ecletica-1322	5	23	biological	biological	ADJ
ecletica-1322	5	24	evaluation	evaluation	NOUN
ecletica-1322	5	25	of	of	ADP
ecletica-1322	5	26	selected	select	VERB
ecletica-1322	5	27	metronidazole	metronidazole	NOUN
ecletica-1322	5	28	derivatives	derivative	NOUN
ecletica-1322	5	29	as	as	ADP
ecletica-1322	5	30	anti	anti	ADJ
ecletica-1322	5	31	-	-	ADJ
ecletica-1322	5	32	nitroreductase	nitroreductase	NOUN
ecletica-1322	5	33	via	via	ADP
ecletica-1322	5	34	in	in	ADP
ecletica-1322	5	35	silico	silico	NOUN
ecletica-1322	5	36	approach	approach	NOUN
ecletica-1322	5	37	moriam	moriam	PROPN
ecletica-1322	5	38	dasola	dasola	PROPN
ecletica-1322	5	39	adeoye1	adeoye1	PROPN
ecletica-1322	5	40	,	,	PUNCT
ecletica-1322	5	41	abel	abel	PROPN
ecletica-1322	5	42	kolawole	kolawole	VERB
ecletica-1322	5	43	oyebamiji2	oyebamiji2	PROPN
ecletica-1322	5	44	+	+	PROPN
ecletica-1322	5	45	,	,	PUNCT
ecletica-1322	5	46	mojeed	mojee	VERB
ecletica-1322	5	47	ayoola	ayoola	PROPN
ecletica-1322	5	48	ashiru1	ashiru1	NOUN
ecletica-1322	5	49	,	,	PUNCT
ecletica-1322	5	50	rasheed	rasheed	VERB
ecletica-1322	5	51	adewale	adewale	PROPN
ecletica-1322	5	52	adigun1	adigun1	PROPN
ecletica-1322	5	53	,	,	PUNCT
ecletica-1322	5	54	olabisi	olabisi	ADJ
ecletica-1322	5	55	hadijat	hadijat	PROPN
ecletica-1322	5	56	olalere1	olalere1	PROPN
ecletica-1322	5	57	,	,	PUNCT
ecletica-1322	5	58	banjo	banjo	NOUN
ecletica-1322	5	59	semire3	semire3	NOUN
ecletica-1322	5	60	1	1	NUM
ecletica-1322	5	61	.	.	X
ecletica-1322	5	62	fountain	fountain	NOUN
ecletica-1322	5	63	university	university	NOUN
ecletica-1322	5	64	,	,	PUNCT
ecletica-1322	5	65	faculty	faculty	NOUN
ecletica-1322	5	66	of	of	ADP
ecletica-1322	5	67	science	science	NOUN
ecletica-1322	5	68	,	,	PUNCT
ecletica-1322	5	69	osogbo	osogbo	PROPN
ecletica-1322	5	70	,	,	PUNCT
ecletica-1322	5	71	osun	osun	PROPN
ecletica-1322	5	72	state	state	PROPN
ecletica-1322	5	73	,	,	PUNCT
ecletica-1322	5	74	nigeria	nigeria	PROPN
ecletica-1322	5	75	.	.	PUNCT
ecletica-1322	6	1	2	2	X
ecletica-1322	6	2	.	.	X
ecletica-1322	6	3	bowen	bowen	PROPN
ecletica-1322	6	4	university	university	PROPN
ecletica-1322	6	5	,	,	PUNCT
ecletica-1322	6	6	department	department	NOUN
ecletica-1322	6	7	of	of	ADP
ecletica-1322	6	8	chemistry	chemistry	NOUN
ecletica-1322	6	9	and	and	CCONJ
ecletica-1322	6	10	industrial	industrial	ADJ
ecletica-1322	6	11	chemistry	chemistry	NOUN
ecletica-1322	6	12	,	,	PUNCT
ecletica-1322	6	13	iwo	iwo	PROPN
ecletica-1322	6	14	,	,	PUNCT
ecletica-1322	6	15	nigeria	nigeria	PROPN
ecletica-1322	6	16	.	.	PUNCT
ecletica-1322	7	1	3	3	X
ecletica-1322	7	2	.	.	NUM
ecletica-1322	7	3	ladoke	ladoke	PROPN
ecletica-1322	7	4	akintola	akintola	PROPN
ecletica-1322	7	5	university	university	PROPN
ecletica-1322	7	6	of	of	ADP
ecletica-1322	7	7	technology	technology	NOUN
ecletica-1322	7	8	,	,	PUNCT
ecletica-1322	7	9	faculty	faculty	NOUN
ecletica-1322	7	10	of	of	ADP
ecletica-1322	7	11	pure	pure	ADJ
ecletica-1322	7	12	and	and	CCONJ
ecletica-1322	7	13	applied	applied	ADJ
ecletica-1322	7	14	science	science	NOUN
ecletica-1322	7	15	,	,	PUNCT
ecletica-1322	7	16	ogbomoso	ogbomoso	NOUN
ecletica-1322	7	17	,	,	PUNCT
ecletica-1322	7	18	nigeria	nigeria	PROPN
ecletica-1322	7	19	.	.	PUNCT
ecletica-1322	8	1	+	+	PUNCT
ecletica-1322	8	2	corresponding	correspond	VERB
ecletica-1322	8	3	author	author	NOUN
ecletica-1322	8	4	:	:	PUNCT
ecletica-1322	8	5	abel	abel	PROPN
ecletica-1322	8	6	kolawole	kolawole	PROPN
ecletica-1322	8	7	oyebamiji	oyebamiji	PROPN
ecletica-1322	8	8	,	,	PUNCT
ecletica-1322	8	9	phone	phone	NOUN
ecletica-1322	8	10	:	:	PUNCT
ecletica-1322	8	11	+2348032493676	+2348032493676	NUM
ecletica-1322	8	12	,	,	PUNCT
ecletica-1322	8	13	email	email	NOUN
ecletica-1322	8	14	address	address	NOUN
ecletica-1322	8	15	:	:	PUNCT
ecletica-1322	8	16	abeloyebamiji@gmail.com	abeloyebamiji@gmail.com	X
ecletica-1322	8	17	article	article	NOUN
ecletica-1322	8	18	info	info	NOUN
ecletica-1322	8	19	article	article	NOUN
ecletica-1322	8	20	history	history	NOUN
ecletica-1322	8	21	:	:	PUNCT
ecletica-1322	8	22	received	receive	VERB
ecletica-1322	8	23	:	:	PUNCT
ecletica-1322	8	24	february	february	PROPN
ecletica-1322	8	25	27	27	NUM
ecletica-1322	8	26	,	,	PUNCT
ecletica-1322	8	27	2022	2022	NUM
ecletica-1322	8	28	accepted	accept	VERB
ecletica-1322	8	29	:	:	PUNCT
ecletica-1322	8	30	july	july	PROPN
ecletica-1322	8	31	11	11	NUM
ecletica-1322	8	32	,	,	PUNCT
ecletica-1322	8	33	2022	2022	NUM
ecletica-1322	8	34	published	publish	VERB
ecletica-1322	8	35	:	:	PUNCT
ecletica-1322	8	36	october	october	PROPN
ecletica-1322	8	37	28	28	NUM
ecletica-1322	8	38	,	,	PUNCT
ecletica-1322	8	39	2022	2022	NUM
ecletica-1322	8	40	keywords	keyword	NOUN
ecletica-1322	8	41	:	:	PUNCT
ecletica-1322	8	42	1	1	X
ecletica-1322	8	43	.	.	X
ecletica-1322	8	44	ligand	ligand	PROPN
ecletica-1322	8	45	2	2	NUM
ecletica-1322	8	46	.	.	PUNCT
ecletica-1322	8	47	antibacterial	antibacterial	ADJ
ecletica-1322	8	48	3	3	NUM
ecletica-1322	8	49	.	.	PUNCT
ecletica-1322	9	1	gastric	gastric	ADJ
ecletica-1322	9	2	4	4	NUM
ecletica-1322	9	3	.	.	PUNCT
ecletica-1322	9	4	phytochemicals	phytochemical	NOUN
ecletica-1322	9	5	5	5	NUM
ecletica-1322	9	6	.	.	PUNCT
ecletica-1322	9	7	adme	adme	NOUN
ecletica-1322	9	8	section	section	NOUN
ecletica-1322	9	9	editors	editor	NOUN
ecletica-1322	9	10	:	:	PUNCT
ecletica-1322	9	11	assis	assis	PROPN
ecletica-1322	9	12	vicente	vicente	PROPN
ecletica-1322	9	13	benedetti	benedetti	PROPN
ecletica-1322	9	14	abstract	abstract	PROPN
ecletica-1322	9	15	:	:	PUNCT
ecletica-1322	9	16	the	the	DET
ecletica-1322	9	17	1-(2	1-(2	PROPN
ecletica-1322	9	18	-	-	PUNCT
ecletica-1322	9	19	hydroxyethyl)-2	hydroxyethyl)-2	PROPN
ecletica-1322	9	20	-	-	PUNCT
ecletica-1322	9	21	methyl-5nitroimidazole	methyl-5nitroimidazole	NOUN
ecletica-1322	9	22	(	(	PUNCT
ecletica-1322	9	23	2hmn	2hmn	NOUN
ecletica-1322	9	24	)	)	PUNCT
ecletica-1322	9	25	is	be	AUX
ecletica-1322	9	26	a	a	DET
ecletica-1322	9	27	powerful	powerful	ADJ
ecletica-1322	9	28	antibacterial	antibacterial	ADJ
ecletica-1322	9	29	and	and	CCONJ
ecletica-1322	9	30	antiparasitic	antiparasitic	ADJ
ecletica-1322	9	31	drug	drug	NOUN
ecletica-1322	9	32	used	use	VERB
ecletica-1322	9	33	alongside	alongside	ADP
ecletica-1322	9	34	other	other	ADJ
ecletica-1322	9	35	drugs	drug	NOUN
ecletica-1322	9	36	against	against	ADP
ecletica-1322	9	37	helicobacter	helicobacter	NOUN
ecletica-1322	9	38	pylori	pylori	NOUN
ecletica-1322	9	39	infection	infection	NOUN
ecletica-1322	9	40	and	and	CCONJ
ecletica-1322	9	41	was	be	AUX
ecletica-1322	9	42	investigated	investigate	VERB
ecletica-1322	9	43	the	the	DET
ecletica-1322	9	44	effects	effect	NOUN
ecletica-1322	9	45	of	of	ADP
ecletica-1322	9	46	substituents	substituent	NOUN
ecletica-1322	9	47	:	:	PUNCT
ecletica-1322	9	48	–	–	PUNCT
ecletica-1322	9	49	oh	oh	INTJ
ecletica-1322	9	50	(	(	PUNCT
ecletica-1322	9	51	a	a	NOUN
ecletica-1322	9	52	)	)	PUNCT
ecletica-1322	9	53	,	,	PUNCT
ecletica-1322	9	54	h	h	NOUN
ecletica-1322	9	55	(	(	PUNCT
ecletica-1322	9	56	b	b	NOUN
ecletica-1322	9	57	)	)	PUNCT
ecletica-1322	9	58	,	,	PUNCT
ecletica-1322	9	59	–	–	PUNCT
ecletica-1322	9	60	sph	sph	NOUN
ecletica-1322	9	61	(	(	PUNCT
ecletica-1322	9	62	c	c	NOUN
ecletica-1322	9	63	)	)	PUNCT
ecletica-1322	9	64	,	,	PUNCT
ecletica-1322	9	65	–	–	PUNCT
ecletica-1322	9	66	cooh	cooh	NOUN
ecletica-1322	9	67	(	(	PUNCT
ecletica-1322	9	68	d	d	NOUN
ecletica-1322	9	69	)	)	PUNCT
ecletica-1322	9	70	,	,	PUNCT
ecletica-1322	9	71	–	–	PUNCT
ecletica-1322	9	72	no2	no2	NOUN
ecletica-1322	9	73	(	(	PUNCT
ecletica-1322	9	74	e	e	NOUN
ecletica-1322	9	75	)	)	PUNCT
ecletica-1322	9	76	and	and	CCONJ
ecletica-1322	9	77	–	–	PUNCT
ecletica-1322	9	78	och3	och3	ADJ
ecletica-1322	9	79	(	(	PUNCT
ecletica-1322	9	80	f	f	X
ecletica-1322	9	81	)	)	PUNCT
ecletica-1322	9	82	on	on	ADP
ecletica-1322	9	83	the	the	DET
ecletica-1322	9	84	interactions	interaction	NOUN
ecletica-1322	9	85	of	of	ADP
ecletica-1322	9	86	2hmn	2hmn	PROPN
ecletica-1322	9	87	with	with	ADP
ecletica-1322	9	88	the	the	DET
ecletica-1322	9	89	target	target	NOUN
ecletica-1322	9	90	nitroreductase	nitroreductase	NOUN
ecletica-1322	9	91	rdxa	rdxa	NOUN
ecletica-1322	9	92	protein	protein	NOUN
ecletica-1322	9	93	for	for	ADP
ecletica-1322	9	94	the	the	DET
ecletica-1322	9	95	treatment	treatment	NOUN
ecletica-1322	9	96	of	of	ADP
ecletica-1322	9	97	the	the	DET
ecletica-1322	9	98	infection	infection	NOUN
ecletica-1322	9	99	.	.	PUNCT
ecletica-1322	10	1	spartan	spartan	ADJ
ecletica-1322	10	2	14	14	NUM
ecletica-1322	10	3	(	(	PUNCT
ecletica-1322	10	4	optimization	optimization	NOUN
ecletica-1322	10	5	)	)	PUNCT
ecletica-1322	10	6	,	,	PUNCT
ecletica-1322	10	7	pymol	pymol	PROPN
ecletica-1322	10	8	1.7.4.4	1.7.4.4	NUM
ecletica-1322	10	9	(	(	PUNCT
ecletica-1322	10	10	to	to	PART
ecletica-1322	10	11	treat	treat	VERB
ecletica-1322	10	12	downloaded	download	VERB
ecletica-1322	10	13	protein	protein	NOUN
ecletica-1322	10	14	)	)	PUNCT
ecletica-1322	10	15	,	,	PUNCT
ecletica-1322	10	16	autodock	autodock	NOUN
ecletica-1322	10	17	tool	tool	NOUN
ecletica-1322	10	18	(	(	PUNCT
ecletica-1322	10	19	locate	locate	ADJ
ecletica-1322	10	20	protein	protein	NOUN
ecletica-1322	10	21	binding	bind	VERB
ecletica-1322	10	22	site	site	NOUN
ecletica-1322	10	23	)	)	PUNCT
ecletica-1322	10	24	,	,	PUNCT
ecletica-1322	10	25	autodock	autodock	NOUN
ecletica-1322	10	26	vina	vina	PROPN
ecletica-1322	10	27	1.1.2	1.1.2	NUM
ecletica-1322	10	28	(	(	PUNCT
ecletica-1322	10	29	docking	dock	VERB
ecletica-1322	10	30	calculation	calculation	NOUN
ecletica-1322	10	31	)	)	PUNCT
ecletica-1322	10	32	were	be	AUX
ecletica-1322	10	33	used	use	VERB
ecletica-1322	10	34	to	to	PART
ecletica-1322	10	35	discover	discover	VERB
ecletica-1322	10	36	the	the	DET
ecletica-1322	10	37	nonbonding	nonbonding	NOUN
ecletica-1322	10	38	interaction	interaction	NOUN
ecletica-1322	10	39	between	between	ADP
ecletica-1322	10	40	docked	docked	ADJ
ecletica-1322	10	41	complexes	complex	NOUN
ecletica-1322	10	42	using	use	VERB
ecletica-1322	10	43	swissadme	swissadme	NOUN
ecletica-1322	10	44	and	and	CCONJ
ecletica-1322	10	45	pre	pre	ADJ
ecletica-1322	10	46	-	-	ADJ
ecletica-1322	10	47	admet	admet	ADJ
ecletica-1322	10	48	software	software	NOUN
ecletica-1322	10	49	.	.	PUNCT
ecletica-1322	11	1	the	the	DET
ecletica-1322	11	2	band	band	NOUN
ecletica-1322	11	3	gaps	gap	VERB
ecletica-1322	11	4	order	order	NOUN
ecletica-1322	11	5	for	for	ADP
ecletica-1322	11	6	the	the	DET
ecletica-1322	11	7	studied	study	VERB
ecletica-1322	11	8	compounds	compound	NOUN
ecletica-1322	11	9	were	be	AUX
ecletica-1322	11	10	c	c	X
ecletica-1322	11	11	<	<	X
ecletica-1322	11	12	a	a	PRON
ecletica-1322	11	13	<	<	X
ecletica-1322	11	14	f	f	X
ecletica-1322	11	15	<	<	X
ecletica-1322	11	16	b	b	X
ecletica-1322	11	17	<	<	X
ecletica-1322	11	18	d	d	X
ecletica-1322	11	19	<	<	X
ecletica-1322	11	20	e	e	NOUN
ecletica-1322	11	21	,	,	PUNCT
ecletica-1322	11	22	a	a	DET
ecletica-1322	11	23	probability	probability	NOUN
ecletica-1322	11	24	of	of	ADP
ecletica-1322	11	25	highest	high	ADJ
ecletica-1322	11	26	charge	charge	NOUN
ecletica-1322	11	27	distribution	distribution	NOUN
ecletica-1322	11	28	and	and	CCONJ
ecletica-1322	11	29	activity	activity	NOUN
ecletica-1322	11	30	for	for	ADP
ecletica-1322	11	31	sph	sph	NOUN
ecletica-1322	11	32	substituted	substitute	VERB
ecletica-1322	11	33	derivatives	derivative	NOUN
ecletica-1322	11	34	and	and	CCONJ
ecletica-1322	11	35	the	the	DET
ecletica-1322	11	36	ligands	ligand	NOUN
ecletica-1322	11	37	conformed	conform	VERB
ecletica-1322	11	38	to	to	ADP
ecletica-1322	11	39	the	the	DET
ecletica-1322	11	40	lipinski	lipinski	PROPN
ecletica-1322	11	41	’s	’s	PART
ecletica-1322	11	42	rule	rule	NOUN
ecletica-1322	11	43	of	of	ADP
ecletica-1322	11	44	five	five	NUM
ecletica-1322	11	45	.	.	PUNCT
ecletica-1322	12	1	compounds	compound	NOUN
ecletica-1322	12	2	d	d	NOUN
ecletica-1322	12	3	and	and	CCONJ
ecletica-1322	12	4	e	e	NOUN
ecletica-1322	12	5	are	be	AUX
ecletica-1322	12	6	noninhibitors	noninhibitor	NOUN
ecletica-1322	12	7	and	and	CCONJ
ecletica-1322	12	8	nonsubstrate	nonsubstrate	VERB
ecletica-1322	12	9	for	for	ADP
ecletica-1322	12	10	cytochrome	cytochrome	ADJ
ecletica-1322	12	11	p450	p450	PROPN
ecletica-1322	12	12	2c9	2c9	NUM
ecletica-1322	12	13	,	,	PUNCT
ecletica-1322	12	14	p450	p450	PROPN
ecletica-1322	12	15	2d6	2d6	NUM
ecletica-1322	12	16	,	,	PUNCT
ecletica-1322	12	17	p450	p450	PROPN
ecletica-1322	12	18	2c19	2c19	NOUN
ecletica-1322	12	19	with	with	ADP
ecletica-1322	12	20	the	the	DET
ecletica-1322	12	21	same	same	ADJ
ecletica-1322	12	22	efficient	efficient	ADJ
ecletica-1322	12	23	calculated	calculate	VERB
ecletica-1322	12	24	binding	bind	VERB
ecletica-1322	12	25	affinity	affinity	NOUN
ecletica-1322	12	26	(	(	PUNCT
ecletica-1322	12	27	–	–	PUNCT
ecletica-1322	12	28	21.3	21.3	NUM
ecletica-1322	12	29	kj	kj	NOUN
ecletica-1322	12	30	mol–1	mol–1	PROPN
ecletica-1322	12	31	)	)	PUNCT
ecletica-1322	12	32	and	and	CCONJ
ecletica-1322	12	33	inhibition	inhibition	VERB
ecletica-1322	12	34	constant	constant	ADJ
ecletica-1322	12	35	(	(	PUNCT
ecletica-1322	12	36	7.8	7.8	NUM
ecletica-1322	12	37	)	)	PUNCT
ecletica-1322	12	38	comparable	comparable	ADJ
ecletica-1322	12	39	to	to	ADP
ecletica-1322	12	40	the	the	DET
ecletica-1322	12	41	standard	standard	ADJ
ecletica-1322	12	42	compound	compound	NOUN
ecletica-1322	12	43	a.	a.	PROPN
ecletica-1322	12	44	https://revista.iq.unesp.br/index.php/ecletica	https://revista.iq.unesp.br/index.php/ecletica	PROPN
ecletica-1322	12	45	https://doi.org/10.26850/1678-4618eqj.v47.4.2022.p27-36	https://doi.org/10.26850/1678-4618eqj.v47.4.2022.p27-36	PROPN
ecletica-1322	12	46	mailto:abeloyebamiji@gmail.com	mailto:abeloyebamiji@gmail.com	X
ecletica-1322	13	1	https://orcid.org/0000-0002-1274-9452	https://orcid.org/0000-0002-1274-9452	VERB
ecletica-1322	13	2	https://orcid.org/0000-0002-8932-6327	https://orcid.org/0000-0002-8932-6327	ADJ
ecletica-1322	13	3	https://orcid.org/0000-0002-6742-4698	https://orcid.org/0000-0002-6742-4698	NOUN
ecletica-1322	13	4	https://orcid.org/0000-0002-9588-4966	https://orcid.org/0000-0002-9588-4966	NOUN
ecletica-1322	13	5	https://orcid.org/0000-0001-6885-0253	https://orcid.org/0000-0001-6885-0253	VERB
ecletica-1322	13	6	https://orcid.org/0000-0002-4173-9165	https://orcid.org/0000-0002-4173-9165	ADJ
ecletica-1322	13	7	original	original	ADJ
ecletica-1322	13	8	article	article	NOUN
ecletica-1322	13	9	revista.iq.unesp.br	revista.iq.unesp.br	PROPN
ecletica-1322	13	10	28	28	NUM
ecletica-1322	13	11	eclética	eclética	PROPN
ecletica-1322	13	12	química	química	PROPN
ecletica-1322	13	13	journal	journal	PROPN
ecletica-1322	13	14	,	,	PUNCT
ecletica-1322	13	15	vol	vol	NOUN
ecletica-1322	13	16	.	.	PROPN
ecletica-1322	14	1	47	47	NUM
ecletica-1322	14	2	,	,	PUNCT
ecletica-1322	14	3	n.	n.	NOUN
ecletica-1322	14	4	4	4	NUM
ecletica-1322	14	5	,	,	PUNCT
ecletica-1322	14	6	2022	2022	NUM
ecletica-1322	14	7	,	,	PUNCT
ecletica-1322	14	8	27	27	NUM
ecletica-1322	14	9	-	-	SYM
ecletica-1322	14	10	36	36	NUM
ecletica-1322	14	11	issn	issn	NOUN
ecletica-1322	14	12	:	:	PUNCT
ecletica-1322	14	13	1678	1678	NUM
ecletica-1322	14	14	-	-	SYM
ecletica-1322	14	15	4618	4618	NUM
ecletica-1322	14	16	doi	doi	NOUN
ecletica-1322	14	17	:	:	PUNCT
ecletica-1322	14	18	10.26850/1678	10.26850/1678	NUM
ecletica-1322	14	19	-	-	SYM
ecletica-1322	14	20	4618eqj.v47.4.2022.p27	4618eqj.v47.4.2022.p27	NUM
ecletica-1322	14	21	-	-	PUNCT
ecletica-1322	14	22	36	36	NUM
ecletica-1322	14	23	1	1	NUM
ecletica-1322	14	24	.	.	PUNCT
ecletica-1322	15	1	introduction	introduction	NOUN
ecletica-1322	15	2	helicobacter	helicobacter	NOUN
ecletica-1322	15	3	pylori	pylori	NOUN
ecletica-1322	15	4	(	(	PUNCT
ecletica-1322	15	5	h.	h.	PROPN
ecletica-1322	15	6	pylori	pylori	PROPN
ecletica-1322	15	7	)	)	PUNCT
ecletica-1322	15	8	,	,	PUNCT
ecletica-1322	15	9	a	a	DET
ecletica-1322	15	10	microaerophilic	microaerophilic	ADJ
ecletica-1322	15	11	gram	gram	NOUN
ecletica-1322	15	12	-	-	PUNCT
ecletica-1322	15	13	negative	negative	ADJ
ecletica-1322	15	14	bacterium	bacterium	NOUN
ecletica-1322	15	15	,	,	PUNCT
ecletica-1322	15	16	has	have	AUX
ecletica-1322	15	17	been	be	AUX
ecletica-1322	15	18	described	describe	VERB
ecletica-1322	15	19	as	as	ADP
ecletica-1322	15	20	the	the	DET
ecletica-1322	15	21	first	first	ADJ
ecletica-1322	15	22	formally	formally	ADV
ecletica-1322	15	23	recognized	recognize	VERB
ecletica-1322	15	24	carcinogenic	carcinogenic	ADJ
ecletica-1322	15	25	bacterial	bacterial	ADJ
ecletica-1322	15	26	,	,	PUNCT
ecletica-1322	15	27	and	and	CCONJ
ecletica-1322	15	28	one	one	NUM
ecletica-1322	15	29	of	of	ADP
ecletica-1322	15	30	the	the	DET
ecletica-1322	15	31	most	most	ADV
ecletica-1322	15	32	successful	successful	ADJ
ecletica-1322	15	33	human	human	ADJ
ecletica-1322	15	34	pathogens	pathogen	NOUN
ecletica-1322	15	35	which	which	PRON
ecletica-1322	15	36	is	be	AUX
ecletica-1322	15	37	believed	believe	VERB
ecletica-1322	15	38	to	to	PART
ecletica-1322	15	39	be	be	AUX
ecletica-1322	15	40	transmitted	transmit	VERB
ecletica-1322	15	41	from	from	ADP
ecletica-1322	15	42	person	person	NOUN
ecletica-1322	15	43	to	to	ADP
ecletica-1322	15	44	person	person	NOUN
ecletica-1322	15	45	through	through	ADP
ecletica-1322	15	46	closed	closed	ADJ
ecletica-1322	15	47	contact	contact	NOUN
ecletica-1322	15	48	and	and	CCONJ
ecletica-1322	15	49	exposure	exposure	NOUN
ecletica-1322	15	50	to	to	ADP
ecletica-1322	15	51	fecal	fecal	ADJ
ecletica-1322	15	52	matters	matter	NOUN
ecletica-1322	15	53	or	or	CCONJ
ecletica-1322	15	54	vomit	vomit	NOUN
ecletica-1322	15	55	(	(	PUNCT
ecletica-1322	15	56	fig	fig	NOUN
ecletica-1322	15	57	.	.	NOUN
ecletica-1322	16	1	1	1	NUM
ecletica-1322	16	2	)	)	PUNCT
ecletica-1322	16	3	(	(	PUNCT
ecletica-1322	16	4	bürgers	bürger	NOUN
ecletica-1322	16	5	et	et	PROPN
ecletica-1322	16	6	al	al	PROPN
ecletica-1322	16	7	.	.	PROPN
ecletica-1322	16	8	,	,	PUNCT
ecletica-1322	16	9	2008	2008	NUM
ecletica-1322	16	10	;	;	PUNCT
ecletica-1322	16	11	kayali	kayali	VERB
ecletica-1322	16	12	et	et	PROPN
ecletica-1322	16	13	al	al	PROPN
ecletica-1322	16	14	.	.	PROPN
ecletica-1322	16	15	,	,	PUNCT
ecletica-1322	16	16	2018	2018	NUM
ecletica-1322	16	17	)	)	PUNCT
ecletica-1322	16	18	.	.	PUNCT
ecletica-1322	17	1	these	these	DET
ecletica-1322	17	2	bacteria	bacteria	NOUN
ecletica-1322	17	3	are	be	AUX
ecletica-1322	17	4	typically	typically	ADV
ecletica-1322	17	5	found	find	VERB
ecletica-1322	17	6	in	in	ADP
ecletica-1322	17	7	the	the	DET
ecletica-1322	17	8	mucous	mucous	ADJ
ecletica-1322	17	9	layer	layer	NOUN
ecletica-1322	17	10	that	that	PRON
ecletica-1322	17	11	covers	cover	VERB
ecletica-1322	17	12	and	and	CCONJ
ecletica-1322	17	13	protects	protect	VERB
ecletica-1322	17	14	the	the	DET
ecletica-1322	17	15	stomach	stomach	NOUN
ecletica-1322	17	16	and	and	CCONJ
ecletica-1322	17	17	small	small	ADJ
ecletica-1322	17	18	intestine	intestine	NOUN
ecletica-1322	17	19	’s	’s	PART
ecletica-1322	17	20	tissues	tissue	NOUN
ecletica-1322	17	21	(	(	PUNCT
ecletica-1322	17	22	houghton	houghton	PROPN
ecletica-1322	17	23	and	and	CCONJ
ecletica-1322	17	24	wang	wang	PROPN
ecletica-1322	17	25	,	,	PUNCT
ecletica-1322	17	26	2005	2005	NUM
ecletica-1322	17	27	)	)	PUNCT
ecletica-1322	17	28	.	.	PUNCT
ecletica-1322	18	1	its	its	PRON
ecletica-1322	18	2	infection	infection	NOUN
ecletica-1322	18	3	,	,	PUNCT
ecletica-1322	18	4	by	by	ADP
ecletica-1322	18	5	inflaming	inflame	VERB
ecletica-1322	18	6	the	the	DET
ecletica-1322	18	7	stomach	stomach	NOUN
ecletica-1322	18	8	’s	’s	PART
ecletica-1322	18	9	inner	inner	ADJ
ecletica-1322	18	10	layer	layer	NOUN
ecletica-1322	18	11	,	,	PUNCT
ecletica-1322	18	12	which	which	PRON
ecletica-1322	18	13	is	be	AUX
ecletica-1322	18	14	a	a	DET
ecletica-1322	18	15	complicated	complicated	ADJ
ecletica-1322	18	16	interplay	interplay	NOUN
ecletica-1322	18	17	between	between	ADP
ecletica-1322	18	18	the	the	DET
ecletica-1322	18	19	bacterial	bacterial	ADJ
ecletica-1322	18	20	,	,	PUNCT
ecletica-1322	18	21	the	the	DET
ecletica-1322	18	22	host	host	NOUN
ecletica-1322	18	23	,	,	PUNCT
ecletica-1322	18	24	and	and	CCONJ
ecletica-1322	18	25	environmental	environmental	ADJ
ecletica-1322	18	26	factors	factor	NOUN
ecletica-1322	18	27	,	,	PUNCT
ecletica-1322	18	28	has	have	AUX
ecletica-1322	18	29	been	be	AUX
ecletica-1322	18	30	established	establish	VERB
ecletica-1322	18	31	to	to	PART
ecletica-1322	18	32	be	be	AUX
ecletica-1322	18	33	the	the	DET
ecletica-1322	18	34	key	key	ADJ
ecletica-1322	18	35	factor	factor	NOUN
ecletica-1322	18	36	with	with	ADP
ecletica-1322	18	37	various	various	ADJ
ecletica-1322	18	38	gastric	gastric	ADJ
ecletica-1322	18	39	diseases	disease	NOUN
ecletica-1322	18	40	such	such	ADJ
ecletica-1322	18	41	as	as	ADP
ecletica-1322	18	42	chronic	chronic	ADJ
ecletica-1322	18	43	gastritis	gastritis	NOUN
ecletica-1322	18	44	,	,	PUNCT
ecletica-1322	18	45	peptic	peptic	ADJ
ecletica-1322	18	46	ulcers	ulcer	NOUN
ecletica-1322	18	47	,	,	PUNCT
ecletica-1322	18	48	and	and	CCONJ
ecletica-1322	18	49	gastric	gastric	ADJ
ecletica-1322	18	50	mucosa	mucosa	NOUN
ecletica-1322	18	51	-	-	PUNCT
ecletica-1322	18	52	associated	associate	VERB
ecletica-1322	18	53	lymphoid	lymphoid	ADJ
ecletica-1322	18	54	tissue	tissue	NOUN
ecletica-1322	18	55	(	(	PUNCT
ecletica-1322	18	56	malt	malt	NOUN
ecletica-1322	18	57	)	)	PUNCT
ecletica-1322	18	58	lymphoma	lymphoma	NOUN
ecletica-1322	18	59	(	(	PUNCT
ecletica-1322	18	60	jemilohun	jemilohun	PROPN
ecletica-1322	18	61	and	and	CCONJ
ecletica-1322	18	62	otegbayo	otegbayo	PROPN
ecletica-1322	18	63	,	,	PUNCT
ecletica-1322	18	64	2016	2016	NUM
ecletica-1322	18	65	;	;	PUNCT
ecletica-1322	18	66	wu	wu	PROPN
ecletica-1322	18	67	et	et	PROPN
ecletica-1322	18	68	al	al	PROPN
ecletica-1322	18	69	.	.	PROPN
ecletica-1322	18	70	,	,	PUNCT
ecletica-1322	18	71	2009	2009	NUM
ecletica-1322	18	72	)	)	PUNCT
ecletica-1322	18	73	.	.	PUNCT
ecletica-1322	19	1	although	although	SCONJ
ecletica-1322	19	2	,	,	PUNCT
ecletica-1322	19	3	many	many	ADJ
ecletica-1322	19	4	other	other	ADJ
ecletica-1322	19	5	factors	factor	NOUN
ecletica-1322	19	6	,	,	PUNCT
ecletica-1322	19	7	such	such	ADJ
ecletica-1322	19	8	as	as	ADP
ecletica-1322	19	9	the	the	DET
ecletica-1322	19	10	persistent	persistent	ADJ
ecletica-1322	19	11	use	use	NOUN
ecletica-1322	19	12	of	of	ADP
ecletica-1322	19	13	anti	anti	ADJ
ecletica-1322	19	14	-	-	ADJ
ecletica-1322	19	15	inflammatory	inflammatory	ADJ
ecletica-1322	19	16	pain	pain	NOUN
ecletica-1322	19	17	relievers	reliever	NOUN
ecletica-1322	19	18	,	,	PUNCT
ecletica-1322	19	19	including	include	VERB
ecletica-1322	19	20	aspirin	aspirin	NOUN
ecletica-1322	19	21	,	,	PUNCT
ecletica-1322	19	22	are	be	AUX
ecletica-1322	19	23	responsible	responsible	ADJ
ecletica-1322	19	24	for	for	ADP
ecletica-1322	19	25	peptic	peptic	ADJ
ecletica-1322	19	26	ulcer	ulcer	NOUN
ecletica-1322	19	27	diseases	disease	NOUN
ecletica-1322	19	28	(	(	PUNCT
ecletica-1322	19	29	bürgers	bürger	NOUN
ecletica-1322	19	30	et	et	PROPN
ecletica-1322	19	31	al	al	PROPN
ecletica-1322	19	32	.	.	PROPN
ecletica-1322	19	33	,	,	PUNCT
ecletica-1322	19	34	2008	2008	NUM
ecletica-1322	19	35	)	)	PUNCT
ecletica-1322	19	36	.	.	PUNCT
ecletica-1322	20	1	the	the	DET
ecletica-1322	20	2	clinical	clinical	ADJ
ecletica-1322	20	3	use	use	NOUN
ecletica-1322	20	4	of	of	ADP
ecletica-1322	20	5	many	many	ADJ
ecletica-1322	20	6	5	5	NUM
ecletica-1322	20	7	-	-	PUNCT
ecletica-1322	20	8	nitroimidazoles	nitroimidazole	NOUN
ecletica-1322	20	9	derivatives	derivative	NOUN
ecletica-1322	20	10	,	,	PUNCT
ecletica-1322	20	11	especially	especially	ADV
ecletica-1322	20	12	metronidazole	metronidazole	NOUN
ecletica-1322	20	13	[	[	X
ecletica-1322	20	14	1-(2hydroxyethyl)-2	1-(2hydroxyethyl)-2	NUM
ecletica-1322	20	15	-	-	PUNCT
ecletica-1322	20	16	methyl-5	methyl-5	NOUN
ecletica-1322	20	17	-	-	PUNCT
ecletica-1322	20	18	nitroimidazole	nitroimidazole	NOUN
ecletica-1322	20	19	]	]	PUNCT
ecletica-1322	20	20	(	(	PUNCT
ecletica-1322	20	21	2hmn	2hmn	NOUN
ecletica-1322	20	22	)	)	PUNCT
ecletica-1322	20	23	as	as	ADP
ecletica-1322	20	24	antibiotic	antibiotic	ADJ
ecletica-1322	20	25	for	for	ADP
ecletica-1322	20	26	the	the	DET
ecletica-1322	20	27	effective	effective	ADJ
ecletica-1322	20	28	treatment	treatment	NOUN
ecletica-1322	20	29	of	of	ADP
ecletica-1322	20	30	patients	patient	NOUN
ecletica-1322	20	31	with	with	ADP
ecletica-1322	20	32	h.	h.	PROPN
ecletica-1322	20	33	pylori	pylori	NOUN
ecletica-1322	20	34	linked	link	VERB
ecletica-1322	20	35	gastritis	gastritis	NOUN
ecletica-1322	20	36	and	and	CCONJ
ecletica-1322	20	37	peptic	peptic	ADJ
ecletica-1322	20	38	ulcer	ulcer	NOUN
ecletica-1322	20	39	ailment	ailment	NOUN
ecletica-1322	20	40	,	,	PUNCT
ecletica-1322	20	41	has	have	AUX
ecletica-1322	20	42	been	be	AUX
ecletica-1322	20	43	listed	list	VERB
ecletica-1322	20	44	and	and	CCONJ
ecletica-1322	20	45	approved	approve	VERB
ecletica-1322	20	46	by	by	ADP
ecletica-1322	20	47	the	the	DET
ecletica-1322	20	48	world	world	PROPN
ecletica-1322	20	49	health	health	PROPN
ecletica-1322	20	50	organization	organization	PROPN
ecletica-1322	20	51	.	.	PUNCT
ecletica-1322	21	1	metronidazole	metronidazole	NOUN
ecletica-1322	21	2	(	(	PUNCT
ecletica-1322	21	3	a	a	NOUN
ecletica-1322	21	4	)	)	PUNCT
ecletica-1322	21	5	(	(	PUNCT
ecletica-1322	21	6	fig	fig	NOUN
ecletica-1322	21	7	.	.	NOUN
ecletica-1322	21	8	2	2	NUM
ecletica-1322	21	9	)	)	PUNCT
ecletica-1322	21	10	has	have	AUX
ecletica-1322	21	11	also	also	ADV
ecletica-1322	21	12	been	be	AUX
ecletica-1322	21	13	used	use	VERB
ecletica-1322	21	14	in	in	ADP
ecletica-1322	21	15	combination	combination	NOUN
ecletica-1322	21	16	with	with	ADP
ecletica-1322	21	17	other	other	ADJ
ecletica-1322	21	18	antibiotics	antibiotic	NOUN
ecletica-1322	21	19	such	such	ADJ
ecletica-1322	21	20	as	as	ADP
ecletica-1322	21	21	tetracycline	tetracycline	NOUN
ecletica-1322	21	22	,	,	PUNCT
ecletica-1322	21	23	amoxicillin	amoxicillin	PROPN
ecletica-1322	21	24	and	and	CCONJ
ecletica-1322	21	25	clarithromycin	clarithromycin	PROPN
ecletica-1322	21	26	to	to	PART
ecletica-1322	21	27	treat	treat	VERB
ecletica-1322	21	28	ulcer	ulcer	NOUN
ecletica-1322	21	29	.	.	PUNCT
ecletica-1322	22	1	however	however	ADV
ecletica-1322	22	2	,	,	PUNCT
ecletica-1322	22	3	it	it	PRON
ecletica-1322	22	4	is	be	AUX
ecletica-1322	22	5	uncommon	uncommon	ADJ
ecletica-1322	22	6	to	to	PART
ecletica-1322	22	7	find	find	VERB
ecletica-1322	22	8	both	both	DET
ecletica-1322	22	9	bacteria	bacteria	NOUN
ecletica-1322	22	10	and	and	CCONJ
ecletica-1322	22	11	protozoa	protozoan	NOUN
ecletica-1322	22	12	to	to	PART
ecletica-1322	22	13	cause	cause	VERB
ecletica-1322	22	14	ulcer	ulcer	NOUN
ecletica-1322	22	15	(	(	PUNCT
ecletica-1322	22	16	houghton	houghton	PROPN
ecletica-1322	22	17	and	and	CCONJ
ecletica-1322	22	18	wang	wang	PROPN
ecletica-1322	22	19	,	,	PUNCT
ecletica-1322	22	20	2005	2005	NUM
ecletica-1322	22	21	)	)	PUNCT
ecletica-1322	22	22	.	.	PUNCT
ecletica-1322	23	1	some	some	DET
ecletica-1322	23	2	studies	study	NOUN
ecletica-1322	23	3	(	(	PUNCT
ecletica-1322	23	4	ghotaslou	ghotaslou	PROPN
ecletica-1322	23	5	et	et	PROPN
ecletica-1322	23	6	al	al	PROPN
ecletica-1322	23	7	.	.	PROPN
ecletica-1322	23	8	,	,	PUNCT
ecletica-1322	23	9	2015	2015	NUM
ecletica-1322	23	10	;	;	PUNCT
ecletica-1322	23	11	kim	kim	PROPN
ecletica-1322	23	12	et	et	PROPN
ecletica-1322	23	13	al	al	PROPN
ecletica-1322	23	14	.	.	PROPN
ecletica-1322	23	15	,	,	PUNCT
ecletica-1322	23	16	2020	2020	NUM
ecletica-1322	23	17	)	)	PUNCT
ecletica-1322	23	18	in	in	ADP
ecletica-1322	23	19	the	the	DET
ecletica-1322	23	20	last	last	ADJ
ecletica-1322	23	21	few	few	ADJ
ecletica-1322	23	22	years	year	NOUN
ecletica-1322	23	23	have	have	AUX
ecletica-1322	23	24	reported	report	VERB
ecletica-1322	23	25	that	that	SCONJ
ecletica-1322	23	26	h.	h.	PROPN
ecletica-1322	23	27	pylori	pylori	NOUN
ecletica-1322	23	28	is	be	AUX
ecletica-1322	23	29	exhibiting	exhibit	VERB
ecletica-1322	23	30	an	an	DET
ecletica-1322	23	31	increasing	increase	VERB
ecletica-1322	23	32	double	double	ADJ
ecletica-1322	23	33	resistance	resistance	NOUN
ecletica-1322	23	34	to	to	ADP
ecletica-1322	23	35	metronidazole	metronidazole	NOUN
ecletica-1322	23	36	and	and	CCONJ
ecletica-1322	23	37	this	this	PRON
ecletica-1322	23	38	has	have	AUX
ecletica-1322	23	39	drawn	draw	VERB
ecletica-1322	23	40	the	the	DET
ecletica-1322	23	41	attention	attention	NOUN
ecletica-1322	23	42	many	many	ADJ
ecletica-1322	23	43	researchers	researcher	NOUN
ecletica-1322	23	44	to	to	PART
ecletica-1322	23	45	study	study	VERB
ecletica-1322	23	46	physiological	physiological	ADJ
ecletica-1322	23	47	and	and	CCONJ
ecletica-1322	23	48	pharmacological	pharmacological	ADJ
ecletica-1322	23	49	significance	significance	NOUN
ecletica-1322	23	50	of	of	ADP
ecletica-1322	23	51	some	some	DET
ecletica-1322	23	52	metronidazole	metronidazole	NOUN
ecletica-1322	23	53	and	and	CCONJ
ecletica-1322	23	54	its	its	PRON
ecletica-1322	23	55	derivatives	derivative	NOUN
ecletica-1322	23	56	(	(	PUNCT
ecletica-1322	23	57	alawadi	alawadi	NOUN
ecletica-1322	23	58	et	et	PROPN
ecletica-1322	23	59	al	al	PROPN
ecletica-1322	23	60	.	.	PROPN
ecletica-1322	23	61	,	,	PUNCT
ecletica-1322	23	62	2015	2015	NUM
ecletica-1322	23	63	)	)	PUNCT
ecletica-1322	23	64	.	.	PUNCT
ecletica-1322	24	1	to	to	PART
ecletica-1322	24	2	contribute	contribute	VERB
ecletica-1322	24	3	to	to	ADP
ecletica-1322	24	4	this	this	DET
ecletica-1322	24	5	ongoing	ongoing	ADJ
ecletica-1322	24	6	area	area	NOUN
ecletica-1322	24	7	of	of	ADP
ecletica-1322	24	8	research	research	NOUN
ecletica-1322	24	9	,	,	PUNCT
ecletica-1322	24	10	this	this	DET
ecletica-1322	24	11	study	study	NOUN
ecletica-1322	24	12	investigates	investigate	VERB
ecletica-1322	24	13	the	the	DET
ecletica-1322	24	14	relative	relative	ADJ
ecletica-1322	24	15	substituents	substituent	NOUN
ecletica-1322	24	16	’	'	PUNCT
ecletica-1322	24	17	effects	effect	NOUN
ecletica-1322	24	18	on	on	ADP
ecletica-1322	24	19	the	the	DET
ecletica-1322	24	20	interactions	interaction	NOUN
ecletica-1322	24	21	of	of	ADP
ecletica-1322	24	22	some	some	DET
ecletica-1322	24	23	nitroimidazole	nitroimidazole	ADJ
ecletica-1322	24	24	derivatives	derivative	NOUN
ecletica-1322	24	25	on	on	ADP
ecletica-1322	24	26	the	the	DET
ecletica-1322	24	27	target	target	NOUN
ecletica-1322	24	28	;	;	PUNCT
ecletica-1322	24	29	nitroreductase	nitroreductase	NOUN
ecletica-1322	24	30	rdxa	rdxa	NOUN
ecletica-1322	24	31	proteins	protein	NOUN
ecletica-1322	24	32	(	(	PUNCT
ecletica-1322	24	33	pdb	pdb	NOUN
ecletica-1322	24	34	i	i	PROPN
ecletica-1322	24	35	d	d	PROPN
ecletica-1322	24	36	:	:	PUNCT
ecletica-1322	24	37	3qdl	3qdl	NUM
ecletica-1322	24	38	)	)	PUNCT
ecletica-1322	24	39	.	.	PUNCT
ecletica-1322	25	1	the	the	DET
ecletica-1322	25	2	roles	role	NOUN
ecletica-1322	25	3	of	of	ADP
ecletica-1322	25	4	computational	computational	ADJ
ecletica-1322	25	5	chemistry	chemistry	NOUN
ecletica-1322	25	6	for	for	ADP
ecletica-1322	25	7	the	the	DET
ecletica-1322	25	8	qualitative	qualitative	ADJ
ecletica-1322	25	9	and	and	CCONJ
ecletica-1322	25	10	quantitative	quantitative	ADJ
ecletica-1322	25	11	evaluation	evaluation	NOUN
ecletica-1322	25	12	of	of	ADP
ecletica-1322	25	13	substances	substance	NOUN
ecletica-1322	25	14	and	and	CCONJ
ecletica-1322	25	15	in	in	ADP
ecletica-1322	25	16	almost	almost	ADV
ecletica-1322	25	17	every	every	PRON
ecletica-1322	25	18	field	field	NOUN
ecletica-1322	25	19	of	of	ADP
ecletica-1322	25	20	chemistry	chemistry	NOUN
ecletica-1322	25	21	can	can	AUX
ecletica-1322	25	22	not	not	PART
ecletica-1322	25	23	be	be	AUX
ecletica-1322	25	24	overstated	overstate	VERB
ecletica-1322	25	25	.	.	PUNCT
ecletica-1322	26	1	of	of	ADP
ecletica-1322	26	2	recent	recent	ADJ
ecletica-1322	26	3	,	,	PUNCT
ecletica-1322	26	4	it	it	PRON
ecletica-1322	26	5	is	be	AUX
ecletica-1322	26	6	routinely	routinely	ADV
ecletica-1322	26	7	used	use	VERB
ecletica-1322	26	8	to	to	PART
ecletica-1322	26	9	accelerate	accelerate	VERB
ecletica-1322	26	10	the	the	DET
ecletica-1322	26	11	long	long	ADJ
ecletica-1322	26	12	and	and	CCONJ
ecletica-1322	26	13	costly	costly	ADJ
ecletica-1322	26	14	drug	drug	NOUN
ecletica-1322	26	15	discovery	discovery	NOUN
ecletica-1322	26	16	/	/	SYM
ecletica-1322	26	17	design	design	NOUN
ecletica-1322	26	18	activities	activity	NOUN
ecletica-1322	26	19	,	,	PUNCT
ecletica-1322	26	20	from	from	ADP
ecletica-1322	26	21	drug	drug	NOUN
ecletica-1322	26	22	target	target	NOUN
ecletica-1322	26	23	identification	identification	NOUN
ecletica-1322	26	24	,	,	PUNCT
ecletica-1322	26	25	commonly	commonly	ADV
ecletica-1322	26	26	a	a	DET
ecletica-1322	26	27	receptor	receptor	NOUN
ecletica-1322	26	28	or	or	CCONJ
ecletica-1322	26	29	an	an	DET
ecletica-1322	26	30	enzyme	enzyme	NOUN
ecletica-1322	26	31	,	,	PUNCT
ecletica-1322	26	32	to	to	ADP
ecletica-1322	26	33	the	the	DET
ecletica-1322	26	34	design	design	NOUN
ecletica-1322	26	35	and	and	CCONJ
ecletica-1322	26	36	optimization	optimization	NOUN
ecletica-1322	26	37	of	of	ADP
ecletica-1322	26	38	new	new	ADJ
ecletica-1322	26	39	drug	drug	NOUN
ecletica-1322	26	40	-	-	PUNCT
ecletica-1322	26	41	like	like	ADJ
ecletica-1322	26	42	compounds	compound	NOUN
ecletica-1322	26	43	.	.	PUNCT
ecletica-1322	27	1	thus	thus	ADV
ecletica-1322	27	2	,	,	PUNCT
ecletica-1322	27	3	each	each	DET
ecletica-1322	27	4	computational	computational	ADJ
ecletica-1322	27	5	chemistry	chemistry	NOUN
ecletica-1322	27	6	method	method	NOUN
ecletica-1322	27	7	can	can	AUX
ecletica-1322	27	8	impact	impact	VERB
ecletica-1322	27	9	and	and	CCONJ
ecletica-1322	27	10	accelerate	accelerate	VERB
ecletica-1322	27	11	a	a	DET
ecletica-1322	27	12	given	give	VERB
ecletica-1322	27	13	phase	phase	NOUN
ecletica-1322	27	14	of	of	ADP
ecletica-1322	27	15	the	the	DET
ecletica-1322	27	16	drug	drug	NOUN
ecletica-1322	27	17	discovery	discovery	NOUN
ecletica-1322	27	18	process	process	NOUN
ecletica-1322	27	19	,	,	PUNCT
ecletica-1322	27	20	from	from	ADP
ecletica-1322	27	21	structure	structure	NOUN
ecletica-1322	27	22	-	-	PUNCT
ecletica-1322	27	23	based	base	VERB
ecletica-1322	27	24	drug	drug	NOUN
ecletica-1322	27	25	design	design	NOUN
ecletica-1322	27	26	technique	technique	NOUN
ecletica-1322	27	27	molecular	molecular	ADJ
ecletica-1322	27	28	docking	docking	NOUN
ecletica-1322	27	29	(	(	PUNCT
ecletica-1322	27	30	stimulation	stimulation	NOUN
ecletica-1322	27	31	of	of	ADP
ecletica-1322	27	32	molecular	molecular	ADJ
ecletica-1322	27	33	interaction	interaction	NOUN
ecletica-1322	27	34	and	and	CCONJ
ecletica-1322	27	35	generation	generation	NOUN
ecletica-1322	27	36	of	of	ADP
ecletica-1322	27	37	potent	potent	ADJ
ecletica-1322	27	38	inhibitory	inhibitory	ADJ
ecletica-1322	27	39	ability	ability	NOUN
ecletica-1322	27	40	,	,	PUNCT
ecletica-1322	27	41	i.e.	i.e.	X
ecletica-1322	27	42	,	,	PUNCT
ecletica-1322	27	43	binding	binding	ADJ
ecletica-1322	27	44	affinity	affinity	NOUN
ecletica-1322	27	45	)	)	PUNCT
ecletica-1322	27	46	,	,	PUNCT
ecletica-1322	27	47	molecular	molecular	ADJ
ecletica-1322	27	48	dynamics	dynamic	NOUN
ecletica-1322	27	49	for	for	ADP
ecletica-1322	27	50	hit	hit	VERB
ecletica-1322	27	51	identification	identification	NOUN
ecletica-1322	27	52	and	and	CCONJ
ecletica-1322	27	53	lead	lead	NOUN
ecletica-1322	27	54	generation	generation	NOUN
ecletica-1322	27	55	to	to	ADP
ecletica-1322	27	56	quantitative	quantitative	ADJ
ecletica-1322	27	57	structure	structure	NOUN
ecletica-1322	27	58	-	-	PUNCT
ecletica-1322	27	59	activity	activity	NOUN
ecletica-1322	27	60	relationship	relationship	NOUN
ecletica-1322	27	61	(	(	PUNCT
ecletica-1322	27	62	qsar	qsar	PROPN
ecletica-1322	27	63	)	)	PUNCT
ecletica-1322	27	64	(	(	PUNCT
ecletica-1322	27	65	adejoro	adejoro	VERB
ecletica-1322	27	66	et	et	PROPN
ecletica-1322	27	67	al	al	PROPN
ecletica-1322	27	68	.	.	PROPN
ecletica-1322	27	69	,	,	PUNCT
ecletica-1322	27	70	2016	2016	NUM
ecletica-1322	27	71	)	)	PUNCT
ecletica-1322	27	72	.	.	PUNCT
ecletica-1322	28	1	the	the	DET
ecletica-1322	28	2	quantum	quantum	NOUN
ecletica-1322	28	3	mechanically	mechanically	ADV
ecletica-1322	28	4	derived	derive	VERB
ecletica-1322	28	5	molecular	molecular	ADJ
ecletica-1322	28	6	descriptors	descriptor	NOUN
ecletica-1322	28	7	and	and	CCONJ
ecletica-1322	28	8	physicochemical	physicochemical	ADJ
ecletica-1322	28	9	variables	variable	NOUN
ecletica-1322	28	10	also	also	ADV
ecletica-1322	28	11	dictate	dictate	VERB
ecletica-1322	28	12	the	the	DET
ecletica-1322	28	13	pharmacokinetics	pharmacokinetic	NOUN
ecletica-1322	28	14	of	of	ADP
ecletica-1322	28	15	any	any	DET
ecletica-1322	28	16	studied	study	VERB
ecletica-1322	28	17	compounds	compound	NOUN
ecletica-1322	28	18	(	(	PUNCT
ecletica-1322	28	19	venkatesh	venkatesh	NOUN
ecletica-1322	28	20	and	and	CCONJ
ecletica-1322	28	21	aravinda	aravinda	NOUN
ecletica-1322	28	22	,	,	PUNCT
ecletica-1322	28	23	2017	2017	NUM
ecletica-1322	28	24	)	)	PUNCT
ecletica-1322	28	25	.	.	PUNCT
ecletica-1322	29	1	these	these	DET
ecletica-1322	29	2	calculated	calculate	VERB
ecletica-1322	29	3	descriptors	descriptor	NOUN
ecletica-1322	29	4	affect	affect	VERB
ecletica-1322	29	5	their	their	PRON
ecletica-1322	29	6	drug	drug	NOUN
ecletica-1322	29	7	-	-	PUNCT
ecletica-1322	29	8	likeness	likeness	NOUN
ecletica-1322	29	9	and	and	CCONJ
ecletica-1322	29	10	,	,	PUNCT
ecletica-1322	29	11	ultimately	ultimately	ADV
ecletica-1322	29	12	,	,	PUNCT
ecletica-1322	29	13	their	their	PRON
ecletica-1322	29	14	absorption	absorption	NOUN
ecletica-1322	29	15	,	,	PUNCT
ecletica-1322	29	16	distribution	distribution	NOUN
ecletica-1322	29	17	,	,	PUNCT
ecletica-1322	29	18	metabolism	metabolism	NOUN
ecletica-1322	29	19	,	,	PUNCT
ecletica-1322	29	20	excretion	excretion	NOUN
ecletica-1322	29	21	and	and	CCONJ
ecletica-1322	29	22	toxicity	toxicity	NOUN
ecletica-1322	29	23	(	(	PUNCT
ecletica-1322	29	24	admet	admet	ADJ
ecletica-1322	29	25	)	)	PUNCT
ecletica-1322	29	26	properties	property	NOUN
ecletica-1322	29	27	,	,	PUNCT
ecletica-1322	29	28	which	which	PRON
ecletica-1322	29	29	are	be	AUX
ecletica-1322	29	30	the	the	DET
ecletica-1322	29	31	key	key	ADJ
ecletica-1322	29	32	factors	factor	NOUN
ecletica-1322	29	33	to	to	PART
ecletica-1322	29	34	be	be	AUX
ecletica-1322	29	35	optimized	optimize	VERB
ecletica-1322	29	36	to	to	PART
ecletica-1322	29	37	generate	generate	VERB
ecletica-1322	29	38	drug	drug	NOUN
ecletica-1322	29	39	candidate	candidate	NOUN
ecletica-1322	29	40	in	in	ADP
ecletica-1322	29	41	clinical	clinical	ADJ
ecletica-1322	29	42	trials	trial	NOUN
ecletica-1322	29	43	(	(	PUNCT
ecletica-1322	29	44	palermo	palermo	NOUN
ecletica-1322	29	45	and	and	CCONJ
ecletica-1322	29	46	vivo	vivo	NOUN
ecletica-1322	29	47	,	,	PUNCT
ecletica-1322	29	48	2015	2015	NUM
ecletica-1322	29	49	)	)	PUNCT
ecletica-1322	29	50	.	.	PUNCT
ecletica-1322	30	1	admet	admet	PROPN
ecletica-1322	30	2	properties	property	NOUN
ecletica-1322	30	3	influence	influence	VERB
ecletica-1322	30	4	the	the	DET
ecletica-1322	30	5	drug	drug	NOUN
ecletica-1322	30	6	levels	level	NOUN
ecletica-1322	30	7	and	and	CCONJ
ecletica-1322	30	8	the	the	DET
ecletica-1322	30	9	kinetics	kinetic	NOUN
ecletica-1322	30	10	of	of	ADP
ecletica-1322	30	11	drug	drug	NOUN
ecletica-1322	30	12	exposures	exposure	NOUN
ecletica-1322	30	13	to	to	ADP
ecletica-1322	30	14	the	the	DET
ecletica-1322	30	15	tissues	tissue	NOUN
ecletica-1322	30	16	,	,	PUNCT
ecletica-1322	30	17	and	and	CCONJ
ecletica-1322	30	18	,	,	PUNCT
ecletica-1322	30	19	hence	hence	ADV
ecletica-1322	30	20	,	,	PUNCT
ecletica-1322	30	21	the	the	DET
ecletica-1322	30	22	performance	performance	NOUN
ecletica-1322	30	23	and	and	CCONJ
ecletica-1322	30	24	pharmacological	pharmacological	ADJ
ecletica-1322	30	25	activities	activity	NOUN
ecletica-1322	30	26	of	of	ADP
ecletica-1322	30	27	compounds	compound	NOUN
ecletica-1322	30	28	as	as	ADP
ecletica-1322	30	29	drugs	drug	NOUN
ecletica-1322	30	30	(	(	PUNCT
ecletica-1322	30	31	patil	patil	PROPN
ecletica-1322	30	32	,	,	PUNCT
ecletica-1322	30	33	2016	2016	NUM
ecletica-1322	30	34	)	)	PUNCT
ecletica-1322	30	35	.	.	PUNCT
ecletica-1322	31	1	this	this	DET
ecletica-1322	31	2	study	study	NOUN
ecletica-1322	31	3	,	,	PUNCT
ecletica-1322	31	4	therefore	therefore	ADV
ecletica-1322	31	5	,	,	PUNCT
ecletica-1322	31	6	determines	determine	VERB
ecletica-1322	31	7	the	the	DET
ecletica-1322	31	8	adme	adme	NOUN
ecletica-1322	31	9	properties	property	NOUN
ecletica-1322	31	10	of	of	ADP
ecletica-1322	31	11	the	the	DET
ecletica-1322	31	12	studied	study	VERB
ecletica-1322	31	13	2hmn	2hmn	PROPN
ecletica-1322	31	14	and	and	CCONJ
ecletica-1322	31	15	some	some	DET
ecletica-1322	31	16	other	other	ADJ
ecletica-1322	31	17	derivatives	derivative	NOUN
ecletica-1322	31	18	of	of	ADP
ecletica-1322	31	19	nitroimidazole	nitroimidazole	NOUN
ecletica-1322	31	20	to	to	PART
ecletica-1322	31	21	investigate	investigate	VERB
ecletica-1322	31	22	their	their	PRON
ecletica-1322	31	23	oralbioavailability	oralbioavailability	NOUN
ecletica-1322	31	24	and	and	CCONJ
ecletica-1322	31	25	drug	drug	NOUN
ecletica-1322	31	26	-	-	PUNCT
ecletica-1322	31	27	likeness	likeness	NOUN
ecletica-1322	31	28	properties	property	NOUN
ecletica-1322	31	29	.	.	PUNCT
ecletica-1322	32	1	figure	figure	NOUN
ecletica-1322	32	2	1	1	NUM
ecletica-1322	32	3	.	.	PUNCT
ecletica-1322	32	4	pictorial	pictorial	ADJ
ecletica-1322	32	5	view	view	NOUN
ecletica-1322	32	6	of	of	ADP
ecletica-1322	32	7	h.	h.	PROPN
ecletica-1322	32	8	pylori	pylori	PROPN
ecletica-1322	32	9	.	.	PUNCT
ecletica-1322	33	1	source	source	NOUN
ecletica-1322	33	2	:	:	PUNCT
ecletica-1322	33	3	bürgers	bürgers	PROPN
ecletica-1322	33	4	et	et	PROPN
ecletica-1322	33	5	al	al	PROPN
ecletica-1322	33	6	.	.	PUNCT
ecletica-1322	33	7	(	(	PUNCT
ecletica-1322	33	8	2008	2008	NUM
ecletica-1322	33	9	)	)	PUNCT
ecletica-1322	33	10	.	.	PUNCT
ecletica-1322	34	1	figure	figure	NOUN
ecletica-1322	34	2	2	2	NUM
ecletica-1322	34	3	.	.	PUNCT
ecletica-1322	35	1	structure	structure	NOUN
ecletica-1322	35	2	of	of	ADP
ecletica-1322	35	3	metronidazole	metronidazole	NOUN
ecletica-1322	36	1	[	[	X
ecletica-1322	36	2	a	a	X
ecletica-1322	36	3	]	]	X
ecletica-1322	36	4	.	.	PUNCT
ecletica-1322	37	1	https://revista.iq.unesp.br/index.php/ecletica	https://revista.iq.unesp.br/index.php/ecletica	PROPN
ecletica-1322	37	2	https://doi.org/10.26850/1678-4618eqj.v47.4.2022.p27-36	https://doi.org/10.26850/1678-4618eqj.v47.4.2022.p27-36	NOUN
ecletica-1322	37	3	original	original	ADJ
ecletica-1322	37	4	article	article	NOUN
ecletica-1322	37	5	revista.iq.unesp.br	revista.iq.unesp.br	PUNCT
ecletica-1322	37	6	29	29	NUM
ecletica-1322	37	7	eclética	eclética	PROPN
ecletica-1322	37	8	química	química	PROPN
ecletica-1322	37	9	journal	journal	PROPN
ecletica-1322	37	10	,	,	PUNCT
ecletica-1322	37	11	vol	vol	NOUN
ecletica-1322	37	12	.	.	PROPN
ecletica-1322	37	13	47	47	NUM
ecletica-1322	37	14	,	,	PUNCT
ecletica-1322	37	15	n.	n.	NOUN
ecletica-1322	37	16	4	4	NUM
ecletica-1322	37	17	,	,	PUNCT
ecletica-1322	37	18	2022	2022	NUM
ecletica-1322	37	19	,	,	PUNCT
ecletica-1322	37	20	27	27	NUM
ecletica-1322	37	21	-	-	SYM
ecletica-1322	37	22	36	36	NUM
ecletica-1322	37	23	issn	issn	NOUN
ecletica-1322	37	24	:	:	PUNCT
ecletica-1322	37	25	1678	1678	NUM
ecletica-1322	37	26	-	-	SYM
ecletica-1322	37	27	4618	4618	NUM
ecletica-1322	37	28	doi	doi	NOUN
ecletica-1322	37	29	:	:	PUNCT
ecletica-1322	37	30	10.26850/1678	10.26850/1678	NUM
ecletica-1322	37	31	-	-	SYM
ecletica-1322	37	32	4618eqj.v47.4.2022.p27	4618eqj.v47.4.2022.p27	NUM
ecletica-1322	37	33	-	-	PUNCT
ecletica-1322	37	34	36	36	NUM
ecletica-1322	37	35	2	2	NUM
ecletica-1322	37	36	.	.	PUNCT
ecletica-1322	37	37	materials	material	NOUN
ecletica-1322	37	38	and	and	CCONJ
ecletica-1322	37	39	methods	method	NOUN
ecletica-1322	37	40	2.1	2.1	NUM
ecletica-1322	37	41	ligand	ligand	NOUN
ecletica-1322	37	42	preparation	preparation	NOUN
ecletica-1322	37	43	the	the	DET
ecletica-1322	37	44	ligands	ligand	NOUN
ecletica-1322	37	45	preparation	preparation	NOUN
ecletica-1322	37	46	and	and	CCONJ
ecletica-1322	37	47	computational	computational	ADJ
ecletica-1322	37	48	analyses	analysis	NOUN
ecletica-1322	37	49	of	of	ADP
ecletica-1322	37	50	the	the	DET
ecletica-1322	37	51	studied	study	VERB
ecletica-1322	37	52	compounds	compound	NOUN
ecletica-1322	37	53	were	be	AUX
ecletica-1322	37	54	carried	carry	VERB
ecletica-1322	37	55	out	out	ADP
ecletica-1322	37	56	with	with	ADP
ecletica-1322	37	57	spartan14	spartan14	NOUN
ecletica-1322	37	58	software	software	NOUN
ecletica-1322	37	59	package	package	NOUN
ecletica-1322	37	60	at	at	ADP
ecletica-1322	37	61	dft	dft	PROPN
ecletica-1322	37	62	/	/	SYM
ecletica-1322	37	63	b3lyp/6	b3lyp/6	PROPN
ecletica-1322	37	64	-	-	NOUN
ecletica-1322	37	65	311	311	NUM
ecletica-1322	37	66	g	g	NOUN
ecletica-1322	37	67	*	*	NOUN
ecletica-1322	37	68	*	*	NOUN
ecletica-1322	37	69	level	level	NOUN
ecletica-1322	37	70	of	of	ADP
ecletica-1322	37	71	theory	theory	NOUN
ecletica-1322	37	72	.	.	PUNCT
ecletica-1322	38	1	using	use	VERB
ecletica-1322	38	2	molecular	molecular	ADJ
ecletica-1322	38	3	editor	editor	NOUN
ecletica-1322	38	4	builder	builder	NOUN
ecletica-1322	38	5	of	of	ADP
ecletica-1322	38	6	spartan	spartan	PROPN
ecletica-1322	38	7	14	14	NUM
ecletica-1322	38	8	,	,	PUNCT
ecletica-1322	38	9	the	the	DET
ecletica-1322	38	10	equilibrium	equilibrium	NOUN
ecletica-1322	38	11	geometries	geometry	NOUN
ecletica-1322	38	12	of	of	ADP
ecletica-1322	38	13	each	each	PRON
ecletica-1322	38	14	of	of	ADP
ecletica-1322	38	15	these	these	DET
ecletica-1322	38	16	compound	compound	NOUN
ecletica-1322	38	17	a	a	DET
ecletica-1322	38	18	–	–	PUNCT
ecletica-1322	38	19	f	f	X
ecletica-1322	38	20	(	(	PUNCT
ecletica-1322	38	21	tab	tab	NOUN
ecletica-1322	38	22	.	.	NOUN
ecletica-1322	38	23	1	1	NUM
ecletica-1322	38	24	)	)	PUNCT
ecletica-1322	38	25	,	,	PUNCT
ecletica-1322	38	26	were	be	AUX
ecletica-1322	38	27	modeled	model	VERB
ecletica-1322	38	28	,	,	PUNCT
ecletica-1322	38	29	and	and	CCONJ
ecletica-1322	38	30	their	their	PRON
ecletica-1322	38	31	structures	structure	NOUN
ecletica-1322	38	32	were	be	AUX
ecletica-1322	38	33	minimized	minimize	VERB
ecletica-1322	38	34	.	.	PUNCT
ecletica-1322	39	1	the	the	DET
ecletica-1322	39	2	compounds	compound	NOUN
ecletica-1322	39	3	were	be	AUX
ecletica-1322	39	4	fully	fully	ADV
ecletica-1322	39	5	optimized	optimize	VERB
ecletica-1322	39	6	(	(	PUNCT
ecletica-1322	39	7	fig	fig	NOUN
ecletica-1322	39	8	.	.	PUNCT
ecletica-1322	40	1	3	3	X
ecletica-1322	40	2	)	)	PUNCT
ecletica-1322	40	3	using	use	VERB
ecletica-1322	40	4	equilibrium	equilibrium	NOUN
ecletica-1322	40	5	geometry	geometry	NOUN
ecletica-1322	40	6	at	at	ADP
ecletica-1322	40	7	ground	ground	NOUN
ecletica-1322	40	8	state	state	NOUN
ecletica-1322	40	9	,	,	PUNCT
ecletica-1322	40	10	with	with	ADP
ecletica-1322	40	11	the	the	DET
ecletica-1322	40	12	features	feature	NOUN
ecletica-1322	40	13	in	in	ADP
ecletica-1322	40	14	the	the	DET
ecletica-1322	40	15	personal	personal	ADJ
ecletica-1322	40	16	computer	computer	NOUN
ecletica-1322	40	17	spartan	spartan	ADJ
ecletica-1322	40	18	14	14	NUM
ecletica-1322	40	19	software	software	NOUN
ecletica-1322	40	20	at	at	ADP
ecletica-1322	40	21	hf	hf	PROPN
ecletica-1322	40	22	-	-	PUNCT
ecletica-1322	40	23	dft	dft	NOUN
ecletica-1322	40	24	self	self	NOUN
ecletica-1322	40	25	-	-	PUNCT
ecletica-1322	40	26	consistent	consistent	ADJ
ecletica-1322	40	27	field	field	NOUN
ecletica-1322	40	28	level	level	NOUN
ecletica-1322	40	29	of	of	ADP
ecletica-1322	40	30	theory	theory	NOUN
ecletica-1322	40	31	,	,	PUNCT
ecletica-1322	40	32	to	to	PART
ecletica-1322	40	33	estimate	estimate	VERB
ecletica-1322	40	34	the	the	DET
ecletica-1322	40	35	physicochemical	physicochemical	ADJ
ecletica-1322	40	36	properties	property	NOUN
ecletica-1322	40	37	;	;	PUNCT
ecletica-1322	40	38	dipole	dipole	NOUN
ecletica-1322	40	39	moment	moment	NOUN
ecletica-1322	40	40	,	,	PUNCT
ecletica-1322	40	41	polarizability	polarizability	NOUN
ecletica-1322	40	42	,	,	PUNCT
ecletica-1322	40	43	solvation	solvation	NOUN
ecletica-1322	40	44	energy	energy	NOUN
ecletica-1322	40	45	,	,	PUNCT
ecletica-1322	40	46	partition	partition	NOUN
ecletica-1322	40	47	coefficient	coefficient	NOUN
ecletica-1322	40	48	(	(	PUNCT
ecletica-1322	40	49	log	log	VERB
ecletica-1322	40	50	p	p	PROPN
ecletica-1322	40	51	)	)	PUNCT
ecletica-1322	40	52	,	,	PUNCT
ecletica-1322	40	53	a	a	DET
ecletica-1322	40	54	measure	measure	NOUN
ecletica-1322	40	55	of	of	ADP
ecletica-1322	40	56	lipophilicity/	lipophilicity/	NUM
ecletica-1322	40	57	hydrophobicity	hydrophobicity	NOUN
ecletica-1322	40	58	,	,	PUNCT
ecletica-1322	40	59	frontier	frontier	NOUN
ecletica-1322	40	60	orbital	orbital	ADJ
ecletica-1322	40	61	energies	energy	NOUN
ecletica-1322	40	62	(	(	PUNCT
ecletica-1322	40	63	ehomo	ehomo	ADJ
ecletica-1322	40	64	and	and	CCONJ
ecletica-1322	40	65	elumo	elumo	ADJ
ecletica-1322	40	66	)	)	PUNCT
ecletica-1322	40	67	of	of	ADP
ecletica-1322	40	68	the	the	DET
ecletica-1322	40	69	studied	study	VERB
ecletica-1322	40	70	compounds	compound	NOUN
ecletica-1322	40	71	.	.	PUNCT
ecletica-1322	41	1	following	follow	VERB
ecletica-1322	41	2	their	their	PRON
ecletica-1322	41	3	geometry	geometry	NOUN
ecletica-1322	41	4	optimization	optimization	NOUN
ecletica-1322	41	5	,	,	PUNCT
ecletica-1322	41	6	their	their	PRON
ecletica-1322	41	7	energy	energy	NOUN
ecletica-1322	41	8	gaps	gap	NOUN
ecletica-1322	41	9	(	(	PUNCT
ecletica-1322	41	10	ehomo	ehomo	ADJ
ecletica-1322	41	11	–	–	PUNCT
ecletica-1322	41	12	elumo	elumo	ADJ
ecletica-1322	41	13	)	)	PUNCT
ecletica-1322	41	14	were	be	AUX
ecletica-1322	41	15	computed	compute	VERB
ecletica-1322	41	16	.	.	PUNCT
ecletica-1322	42	1	the	the	DET
ecletica-1322	42	2	ehomo	ehomo	NOUN
ecletica-1322	42	3	and	and	CCONJ
ecletica-1322	42	4	elumo	elumo	NOUN
ecletica-1322	42	5	of	of	ADP
ecletica-1322	42	6	the	the	DET
ecletica-1322	42	7	modeled	model	VERB
ecletica-1322	42	8	molecules	molecule	NOUN
ecletica-1322	42	9	were	be	AUX
ecletica-1322	42	10	related	relate	VERB
ecletica-1322	42	11	to	to	ADP
ecletica-1322	42	12	the	the	DET
ecletica-1322	42	13	ionization	ionization	NOUN
ecletica-1322	42	14	potential	potential	NOUN
ecletica-1322	42	15	(	(	PUNCT
ecletica-1322	42	16	ip	ip	NOUN
ecletica-1322	42	17	)	)	PUNCT
ecletica-1322	42	18	,	,	PUNCT
ecletica-1322	42	19	the	the	DET
ecletica-1322	42	20	electron	electron	NOUN
ecletica-1322	42	21	affinity	affinity	NOUN
ecletica-1322	42	22	(	(	PUNCT
ecletica-1322	42	23	ea	ea	NOUN
ecletica-1322	42	24	)	)	PUNCT
ecletica-1322	42	25	,	,	PUNCT
ecletica-1322	42	26	and	and	CCONJ
ecletica-1322	42	27	the	the	DET
ecletica-1322	42	28	global	global	ADJ
ecletica-1322	42	29	hardness	hardness	NOUN
ecletica-1322	42	30	(	(	PUNCT
ecletica-1322	42	31	η	η	NOUN
ecletica-1322	42	32	)	)	PUNCT
ecletica-1322	42	33	,	,	PUNCT
ecletica-1322	42	34	using	use	VERB
ecletica-1322	42	35	koopman	koopman	PROPN
ecletica-1322	42	36	’s	’s	PART
ecletica-1322	42	37	theorem	theorem	NOUN
ecletica-1322	42	38	(	(	PUNCT
ecletica-1322	42	39	1–3	1–3	NOUN
ecletica-1322	42	40	)	)	PUNCT
ecletica-1322	42	41	(	(	PUNCT
ecletica-1322	42	42	adeoye	adeoye	VERB
ecletica-1322	42	43	et	et	PROPN
ecletica-1322	42	44	al	al	PROPN
ecletica-1322	42	45	.	.	PROPN
ecletica-1322	42	46	,	,	PUNCT
ecletica-1322	42	47	2019	2019	NUM
ecletica-1322	42	48	)	)	PUNCT
ecletica-1322	42	49	.	.	PUNCT
ecletica-1322	43	1	these	these	DET
ecletica-1322	43	2	descriptors	descriptor	NOUN
ecletica-1322	43	3	help	help	VERB
ecletica-1322	43	4	to	to	PART
ecletica-1322	43	5	predict	predict	VERB
ecletica-1322	43	6	,	,	PUNCT
ecletica-1322	43	7	on	on	ADP
ecletica-1322	43	8	theoretical	theoretical	ADJ
ecletica-1322	43	9	basis	basis	NOUN
ecletica-1322	43	10	,	,	PUNCT
ecletica-1322	43	11	the	the	DET
ecletica-1322	43	12	chemical	chemical	NOUN
ecletica-1322	43	13	activities	activity	NOUN
ecletica-1322	43	14	of	of	ADP
ecletica-1322	43	15	these	these	DET
ecletica-1322	43	16	compounds	compound	NOUN
ecletica-1322	43	17	.	.	PUNCT
ecletica-1322	44	1	figure	figure	NOUN
ecletica-1322	44	2	3	3	NUM
ecletica-1322	44	3	.	.	PUNCT
ecletica-1322	44	4	structures	structure	NOUN
ecletica-1322	44	5	of	of	ADP
ecletica-1322	44	6	(	(	PUNCT
ecletica-1322	44	7	a	a	X
ecletica-1322	44	8	)	)	PUNCT
ecletica-1322	44	9	[	[	X
ecletica-1322	44	10	raw	raw	ADJ
ecletica-1322	44	11	protein	protein	NOUN
ecletica-1322	44	12	(	(	PUNCT
ecletica-1322	44	13	3dql	3dql	NUM
ecletica-1322	44	14	)	)	PUNCT
ecletica-1322	44	15	]	]	PUNCT
ecletica-1322	44	16	and	and	CCONJ
ecletica-1322	44	17	(	(	PUNCT
ecletica-1322	44	18	b	b	X
ecletica-1322	44	19	)	)	PUNCT
ecletica-1322	44	20	[	[	X
ecletica-1322	44	21	cleaned	clean	VERB
ecletica-1322	44	22	protein	protein	NOUN
ecletica-1322	44	23	]	]	PUNCT
ecletica-1322	44	24	.	.	PUNCT
ecletica-1322	45	1	source	source	NOUN
ecletica-1322	45	2	:	:	PUNCT
ecletica-1322	45	3	martínez	martínez	PROPN
ecletica-1322	45	4	-	-	PUNCT
ecletica-1322	45	5	júlvez	júlvez	PROPN
ecletica-1322	45	6	et	et	PROPN
ecletica-1322	45	7	al	al	PROPN
ecletica-1322	45	8	.	.	PROPN
ecletica-1322	45	9	(	(	PUNCT
ecletica-1322	45	10	2012	2012	NUM
ecletica-1322	45	11	)	)	PUNCT
ecletica-1322	45	12	.	.	PUNCT
ecletica-1322	46	1	table	table	NOUN
ecletica-1322	46	2	1	1	NUM
ecletica-1322	46	3	.	.	X
ecletica-1322	46	4	two	two	NUM
ecletica-1322	46	5	-	-	PUNCT
ecletica-1322	46	6	dimensional	dimensional	ADJ
ecletica-1322	46	7	(	(	PUNCT
ecletica-1322	46	8	2d	2d	NOUN
ecletica-1322	46	9	)	)	PUNCT
ecletica-1322	46	10	structures	structure	NOUN
ecletica-1322	46	11	of	of	ADP
ecletica-1322	46	12	the	the	DET
ecletica-1322	46	13	studied	study	VERB
ecletica-1322	46	14	compounds	compound	NOUN
ecletica-1322	46	15	.	.	PUNCT
ecletica-1322	47	1	r1	r1	PROPN
ecletica-1322	47	2	name	name	VERB
ecletica-1322	47	3	a	a	DET
ecletica-1322	47	4	oh	oh	NUM
ecletica-1322	47	5	1-(2	1-(2	PROPN
ecletica-1322	47	6	-	-	PUNCT
ecletica-1322	47	7	hydroxyethyl)-2	hydroxyethyl)-2	PROPN
ecletica-1322	47	8	-	-	PUNCT
ecletica-1322	47	9	methyl-5	methyl-5	NOUN
ecletica-1322	47	10	-	-	PUNCT
ecletica-1322	47	11	nitroimidazole	nitroimidazole	NOUN
ecletica-1322	47	12	b	b	PROPN
ecletica-1322	47	13	h	h	PROPN
ecletica-1322	47	14	n	n	CCONJ
ecletica-1322	47	15	-	-	PUNCT
ecletica-1322	47	16	ethyl-2	ethyl-2	NUM
ecletica-1322	47	17	-	-	PUNCT
ecletica-1322	47	18	methyl-5	methyl-5	NOUN
ecletica-1322	47	19	-	-	PUNCT
ecletica-1322	47	20	nitroimidazole	nitroimidazole	NOUN
ecletica-1322	47	21	c	c	PROPN
ecletica-1322	47	22	sph	sph	PROPN
ecletica-1322	47	23	1-(2	1-(2	PROPN
ecletica-1322	47	24	-	-	PUNCT
ecletica-1322	47	25	thiophenylethyl)-2	thiophenylethyl)-2	PROPN
ecletica-1322	47	26	-	-	PUNCT
ecletica-1322	47	27	methyl-5	methyl-5	NOUN
ecletica-1322	47	28	-	-	PUNCT
ecletica-1322	47	29	nitroimidazole	nitroimidazole	NOUN
ecletica-1322	48	1	d	d	PROPN
ecletica-1322	48	2	cooh	cooh	NOUN
ecletica-1322	48	3	1-(2	1-(2	PROPN
ecletica-1322	48	4	-	-	PUNCT
ecletica-1322	48	5	carboxylethyl)-2	carboxylethyl)-2	PROPN
ecletica-1322	48	6	-	-	PUNCT
ecletica-1322	48	7	methyl-5	methyl-5	NOUN
ecletica-1322	48	8	-	-	PUNCT
ecletica-1322	48	9	nitroimidazole	nitroimidazole	NOUN
ecletica-1322	48	10	e	e	PROPN
ecletica-1322	48	11	no2	no2	PROPN
ecletica-1322	48	12	1-(2	1-(2	PROPN
ecletica-1322	48	13	-	-	PUNCT
ecletica-1322	48	14	nitroethyl)-2	nitroethyl)-2	PROPN
ecletica-1322	48	15	-	-	PUNCT
ecletica-1322	48	16	methyl-5	methyl-5	NOUN
ecletica-1322	48	17	-	-	PUNCT
ecletica-1322	48	18	nitroimidazole	nitroimidazole	NOUN
ecletica-1322	48	19	f	f	PROPN
ecletica-1322	48	20	och3	och3	PROPN
ecletica-1322	48	21	1-(2	1-(2	PROPN
ecletica-1322	48	22	-	-	PUNCT
ecletica-1322	48	23	methoxylethyl)-2	methoxylethyl)-2	PROPN
ecletica-1322	48	24	-	-	PUNCT
ecletica-1322	48	25	methyl-5	methyl-5	NOUN
ecletica-1322	48	26	-	-	PUNCT
ecletica-1322	48	27	nitroimidazole	nitroimidazole	ADJ
ecletica-1322	48	28	2.2	2.2	NUM
ecletica-1322	48	29	preparation	preparation	NOUN
ecletica-1322	48	30	of	of	ADP
ecletica-1322	48	31	the	the	DET
ecletica-1322	48	32	studied	studied	ADJ
ecletica-1322	48	33	receptor	receptor	NOUN
ecletica-1322	48	34	(	(	PUNCT
ecletica-1322	48	35	protein	protein	NOUN
ecletica-1322	48	36	)	)	PUNCT
ecletica-1322	48	37	the	the	DET
ecletica-1322	48	38	target	target	NOUN
ecletica-1322	48	39	protein	protein	NOUN
ecletica-1322	48	40	for	for	ADP
ecletica-1322	48	41	this	this	DET
ecletica-1322	48	42	study	study	NOUN
ecletica-1322	48	43	was	be	AUX
ecletica-1322	48	44	nitroreductase	nitroreductase	NOUN
ecletica-1322	48	45	rdxa	rdxa	NOUN
ecletica-1322	48	46	protein	protein	NOUN
ecletica-1322	48	47	(	(	PUNCT
ecletica-1322	48	48	pdb	pdb	PROPN
ecletica-1322	48	49	i	i	PROPN
ecletica-1322	48	50	d	d	PROPN
ecletica-1322	48	51	:	:	PUNCT
ecletica-1322	48	52	3qdl	3qdl	NUM
ecletica-1322	48	53	)	)	PUNCT
ecletica-1322	48	54	(	(	PUNCT
ecletica-1322	48	55	martínez	martínez	NOUN
ecletica-1322	48	56	-	-	PUNCT
ecletica-1322	48	57	júlvez	júlvez	PROPN
ecletica-1322	48	58	et	et	PROPN
ecletica-1322	48	59	al	al	PROPN
ecletica-1322	48	60	.	.	PROPN
ecletica-1322	48	61	,	,	PUNCT
ecletica-1322	48	62	2012	2012	NUM
ecletica-1322	48	63	)	)	PUNCT
ecletica-1322	48	64	.	.	PUNCT
ecletica-1322	49	1	the	the	DET
ecletica-1322	49	2	3d	3d	PROPN
ecletica-1322	49	3	structure	structure	NOUN
ecletica-1322	49	4	(	(	PUNCT
ecletica-1322	49	5	x	x	NOUN
ecletica-1322	49	6	-	-	NOUN
ecletica-1322	49	7	ray	ray	NOUN
ecletica-1322	49	8	diffraction	diffraction	NOUN
ecletica-1322	49	9	)	)	PUNCT
ecletica-1322	49	10	was	be	AUX
ecletica-1322	49	11	obtained	obtain	VERB
ecletica-1322	49	12	from	from	ADP
ecletica-1322	49	13	the	the	DET
ecletica-1322	49	14	protein	protein	NOUN
ecletica-1322	49	15	data	datum	NOUN
ecletica-1322	49	16	bank	bank	PROPN
ecletica-1322	49	17	and	and	CCONJ
ecletica-1322	49	18	treated	treat	VERB
ecletica-1322	49	19	with	with	ADP
ecletica-1322	49	20	pymol	pymol	PROPN
ecletica-1322	49	21	1.7.4.4	1.7.4.4	NUM
ecletica-1322	49	22	for	for	ADP
ecletica-1322	49	23	the	the	DET
ecletica-1322	49	24	removal	removal	NOUN
ecletica-1322	49	25	of	of	ADP
ecletica-1322	49	26	water	water	NOUN
ecletica-1322	49	27	molecules	molecule	NOUN
ecletica-1322	49	28	and	and	CCONJ
ecletica-1322	49	29	any	any	DET
ecletica-1322	49	30	other	other	ADJ
ecletica-1322	49	31	residues	residue	NOUN
ecletica-1322	49	32	apart	apart	ADV
ecletica-1322	49	33	from	from	ADP
ecletica-1322	49	34	the	the	DET
ecletica-1322	49	35	desired	desire	VERB
ecletica-1322	49	36	molecule	molecule	NOUN
ecletica-1322	49	37	.	.	PUNCT
ecletica-1322	50	1	schrödinger	schrödinger	NOUN
ecletica-1322	50	2	(	(	PUNCT
ecletica-1322	50	3	maestro	maestro	NOUN
ecletica-1322	50	4	12.7	12.7	NUM
ecletica-1322	50	5	)	)	PUNCT
ecletica-1322	50	6	(	(	PUNCT
ecletica-1322	50	7	morakinyo	morakinyo	NOUN
ecletica-1322	50	8	et	et	PROPN
ecletica-1322	50	9	al	al	PROPN
ecletica-1322	50	10	.	.	PROPN
ecletica-1322	50	11	,	,	PUNCT
ecletica-1322	50	12	2022	2022	NUM
ecletica-1322	50	13	)	)	PUNCT
ecletica-1322	50	14	and	and	CCONJ
ecletica-1322	50	15	the	the	DET
ecletica-1322	50	16	https://revista.iq.unesp.br/index.php/ecletica	https://revista.iq.unesp.br/index.php/ecletica	PROPN
ecletica-1322	50	17	https://doi.org/10.26850/1678-4618eqj.v47.4.2022.p27-36	https://doi.org/10.26850/1678-4618eqj.v47.4.2022.p27-36	NOUN
ecletica-1322	50	18	original	original	ADJ
ecletica-1322	50	19	article	article	NOUN
ecletica-1322	50	20	revista.iq.unesp.br	revista.iq.unesp.br	PUNCT
ecletica-1322	50	21	30	30	NUM
ecletica-1322	50	22	eclética	eclética	PROPN
ecletica-1322	50	23	química	química	PROPN
ecletica-1322	50	24	journal	journal	PROPN
ecletica-1322	50	25	,	,	PUNCT
ecletica-1322	50	26	vol	vol	NOUN
ecletica-1322	50	27	.	.	PROPN
ecletica-1322	50	28	47	47	NUM
ecletica-1322	50	29	,	,	PUNCT
ecletica-1322	50	30	n.	n.	NOUN
ecletica-1322	50	31	4	4	NUM
ecletica-1322	50	32	,	,	PUNCT
ecletica-1322	50	33	2022	2022	NUM
ecletica-1322	50	34	,	,	PUNCT
ecletica-1322	50	35	27	27	NUM
ecletica-1322	50	36	-	-	SYM
ecletica-1322	50	37	36	36	NUM
ecletica-1322	50	38	issn	issn	NOUN
ecletica-1322	50	39	:	:	PUNCT
ecletica-1322	50	40	1678	1678	NUM
ecletica-1322	50	41	-	-	SYM
ecletica-1322	50	42	4618	4618	NUM
ecletica-1322	50	43	doi	doi	NOUN
ecletica-1322	50	44	:	:	PUNCT
ecletica-1322	50	45	10.26850/1678	10.26850/1678	NUM
ecletica-1322	50	46	-	-	SYM
ecletica-1322	50	47	4618eqj.v47.4.2022.p27	4618eqj.v47.4.2022.p27	NUM
ecletica-1322	50	48	-	-	PUNCT
ecletica-1322	50	49	36	36	NUM
ecletica-1322	50	50	references	reference	NOUN
ecletica-1322	50	51	therein	therein	ADV
ecletica-1322	50	52	attached	attach	VERB
ecletica-1322	50	53	journals	journal	NOUN
ecletica-1322	50	54	were	be	AUX
ecletica-1322	50	55	used	use	VERB
ecletica-1322	50	56	to	to	PART
ecletica-1322	50	57	determine	determine	VERB
ecletica-1322	50	58	the	the	DET
ecletica-1322	50	59	target	target	NOUN
ecletica-1322	50	60	protein	protein	NOUN
ecletica-1322	50	61	’s	’s	PART
ecletica-1322	50	62	active	active	ADJ
ecletica-1322	50	63	site	site	NOUN
ecletica-1322	50	64	,	,	PUNCT
ecletica-1322	50	65	in	in	ADP
ecletica-1322	50	66	preparation	preparation	NOUN
ecletica-1322	50	67	for	for	ADP
ecletica-1322	50	68	site	site	NOUN
ecletica-1322	50	69	specific	specific	ADJ
ecletica-1322	50	70	docking	docking	NOUN
ecletica-1322	50	71	.	.	PUNCT
ecletica-1322	51	1	the	the	DET
ecletica-1322	51	2	structure	structure	NOUN
ecletica-1322	51	3	of	of	ADP
ecletica-1322	51	4	the	the	DET
ecletica-1322	51	5	raw	raw	ADJ
ecletica-1322	51	6	protein	protein	NOUN
ecletica-1322	51	7	(	(	PUNCT
ecletica-1322	51	8	3dql	3dql	NUM
ecletica-1322	51	9	)	)	PUNCT
ecletica-1322	51	10	from	from	ADP
ecletica-1322	51	11	the	the	DET
ecletica-1322	51	12	data	data	PROPN
ecletica-1322	51	13	bank	bank	PROPN
ecletica-1322	51	14	and	and	CCONJ
ecletica-1322	51	15	the	the	DET
ecletica-1322	51	16	cleaned	clean	VERB
ecletica-1322	51	17	protein	protein	NOUN
ecletica-1322	51	18	are	be	AUX
ecletica-1322	51	19	as	as	SCONJ
ecletica-1322	51	20	presented	present	VERB
ecletica-1322	51	21	in	in	ADP
ecletica-1322	51	22	figs	fig	NOUN
ecletica-1322	51	23	.	.	PUNCT
ecletica-1322	52	1	4a	4a	NOUN
ecletica-1322	52	2	and	and	CCONJ
ecletica-1322	52	3	b.	b.	PROPN
ecletica-1322	52	4	2.3	2.3	NUM
ecletica-1322	52	5	molecular	molecular	ADJ
ecletica-1322	52	6	docking	docking	NOUN
ecletica-1322	52	7	analysis	analysis	NOUN
ecletica-1322	52	8	the	the	DET
ecletica-1322	52	9	optimized	optimize	VERB
ecletica-1322	52	10	compounds	compound	NOUN
ecletica-1322	52	11	were	be	AUX
ecletica-1322	52	12	docked	dock	VERB
ecletica-1322	52	13	into	into	ADP
ecletica-1322	52	14	the	the	DET
ecletica-1322	52	15	active	active	ADJ
ecletica-1322	52	16	pockets	pocket	NOUN
ecletica-1322	52	17	of	of	ADP
ecletica-1322	52	18	the	the	DET
ecletica-1322	52	19	target	target	NOUN
ecletica-1322	52	20	h.	h.	NOUN
ecletica-1322	52	21	pylori	pylori	ADJ
ecletica-1322	52	22	protease	protease	NOUN
ecletica-1322	52	23	;	;	PUNCT
ecletica-1322	52	24	nitroreductase	nitroreductase	NOUN
ecletica-1322	52	25	rdxa	rdxa	NOUN
ecletica-1322	52	26	protein	protein	NOUN
ecletica-1322	52	27	(	(	PUNCT
ecletica-1322	52	28	pdb	pdb	PROPN
ecletica-1322	52	29	i	i	PROPN
ecletica-1322	52	30	d	d	PROPN
ecletica-1322	52	31	:	:	PUNCT
ecletica-1322	52	32	3qdl	3qdl	NUM
ecletica-1322	52	33	)	)	PUNCT
ecletica-1322	52	34	,	,	PUNCT
ecletica-1322	52	35	using	use	VERB
ecletica-1322	52	36	two	two	NUM
ecletica-1322	52	37	softwares	software	NOUN
ecletica-1322	52	38	with	with	ADP
ecletica-1322	52	39	different	different	ADJ
ecletica-1322	52	40	algorithm	algorithm	NOUN
ecletica-1322	52	41	profiles	profile	NOUN
ecletica-1322	52	42	(	(	PUNCT
ecletica-1322	52	43	autodock	autodock	NOUN
ecletica-1322	52	44	vina	vina	NOUN
ecletica-1322	52	45	and	and	CCONJ
ecletica-1322	52	46	discovery	discovery	PROPN
ecletica-1322	52	47	studio	studio	NOUN
ecletica-1322	52	48	)	)	PUNCT
ecletica-1322	52	49	to	to	PART
ecletica-1322	52	50	predict	predict	VERB
ecletica-1322	52	51	their	their	PRON
ecletica-1322	52	52	binding	bind	VERB
ecletica-1322	52	53	abilities	ability	NOUN
ecletica-1322	52	54	with	with	ADP
ecletica-1322	52	55	the	the	DET
ecletica-1322	52	56	studied	studied	ADJ
ecletica-1322	52	57	receptor	receptor	NOUN
ecletica-1322	52	58	(	(	PUNCT
ecletica-1322	52	59	forli	forli	PROPN
ecletica-1322	52	60	et	et	PROPN
ecletica-1322	52	61	al	al	PROPN
ecletica-1322	52	62	.	.	PROPN
ecletica-1322	52	63	,	,	PUNCT
ecletica-1322	52	64	2016	2016	NUM
ecletica-1322	52	65	;	;	PUNCT
ecletica-1322	52	66	roche	roche	PROPN
ecletica-1322	52	67	et	et	PROPN
ecletica-1322	52	68	al	al	PROPN
ecletica-1322	52	69	.	.	PROPN
ecletica-1322	52	70	,	,	PUNCT
ecletica-1322	52	71	2015	2015	NUM
ecletica-1322	52	72	)	)	PUNCT
ecletica-1322	52	73	.	.	PUNCT
ecletica-1322	53	1	the	the	DET
ecletica-1322	53	2	docking	docking	NOUN
ecletica-1322	53	3	process	process	NOUN
ecletica-1322	53	4	mainly	mainly	ADV
ecletica-1322	53	5	involves	involve	VERB
ecletica-1322	53	6	spatial	spatial	ADJ
ecletica-1322	53	7	matching	matching	NOUN
ecletica-1322	53	8	and	and	CCONJ
ecletica-1322	53	9	energy	energy	NOUN
ecletica-1322	53	10	matching	matching	NOUN
ecletica-1322	53	11	(	(	PUNCT
ecletica-1322	53	12	meng	meng	PROPN
ecletica-1322	53	13	et	et	PROPN
ecletica-1322	53	14	al	al	PROPN
ecletica-1322	53	15	.	.	PROPN
ecletica-1322	53	16	,	,	PUNCT
ecletica-1322	53	17	2011	2011	NUM
ecletica-1322	53	18	)	)	PUNCT
ecletica-1322	53	19	between	between	ADP
ecletica-1322	53	20	the	the	DET
ecletica-1322	53	21	ligand	ligand	NOUN
ecletica-1322	53	22	and	and	CCONJ
ecletica-1322	53	23	the	the	DET
ecletica-1322	53	24	receptor	receptor	NOUN
ecletica-1322	53	25	(	(	PUNCT
ecletica-1322	53	26	cleaned	clean	VERB
ecletica-1322	53	27	protein	protein	NOUN
ecletica-1322	53	28	)	)	PUNCT
ecletica-1322	53	29	for	for	ADP
ecletica-1322	53	30	optimal	optimal	ADJ
ecletica-1322	53	31	conformation	conformation	NOUN
ecletica-1322	53	32	.	.	PUNCT
ecletica-1322	54	1	the	the	DET
ecletica-1322	54	2	grid	grid	NOUN
ecletica-1322	54	3	center	center	NOUN
ecletica-1322	54	4	(	(	PUNCT
ecletica-1322	54	5	x	x	SYM
ecletica-1322	54	6	=	=	SYM
ecletica-1322	54	7	16.082	16.082	NUM
ecletica-1322	54	8	,	,	PUNCT
ecletica-1322	54	9	y	y	PROPN
ecletica-1322	54	10	=	=	SYM
ecletica-1322	54	11	4.657	4.657	NUM
ecletica-1322	54	12	,	,	PUNCT
ecletica-1322	54	13	z	z	NOUN
ecletica-1322	54	14	=	=	SYM
ecletica-1322	54	15	10.976	10.976	NUM
ecletica-1322	54	16	)	)	PUNCT
ecletica-1322	54	17	and	and	CCONJ
ecletica-1322	54	18	box	box	NOUN
ecletica-1322	54	19	size	size	NOUN
ecletica-1322	54	20	(	(	PUNCT
ecletica-1322	54	21	x	x	SYM
ecletica-1322	54	22	=	=	SYM
ecletica-1322	54	23	84	84	NUM
ecletica-1322	54	24	,	,	PUNCT
ecletica-1322	54	25	y	y	PROPN
ecletica-1322	54	26	=	=	SYM
ecletica-1322	54	27	94	94	NUM
ecletica-1322	54	28	,	,	PUNCT
ecletica-1322	54	29	z	z	NOUN
ecletica-1322	54	30	=	=	SYM
ecletica-1322	54	31	46	46	NUM
ecletica-1322	54	32	)	)	PUNCT
ecletica-1322	54	33	were	be	AUX
ecletica-1322	54	34	used	use	VERB
ecletica-1322	54	35	.	.	PUNCT
ecletica-1322	55	1	and	and	CCONJ
ecletica-1322	55	2	the	the	DET
ecletica-1322	55	3	spacing	spacing	NOUN
ecletica-1322	55	4	was	be	AUX
ecletica-1322	55	5	set	set	VERB
ecletica-1322	55	6	to	to	PART
ecletica-1322	55	7	be	be	AUX
ecletica-1322	55	8	1.00	1.00	NUM
ecletica-1322	55	9	å	å	NOUN
ecletica-1322	55	10	.	.	PROPN
ecletica-1322	56	1	2.4	2.4	NUM
ecletica-1322	56	2	admet	admet	NOUN
ecletica-1322	56	3	prediction	prediction	NOUN
ecletica-1322	56	4	the	the	DET
ecletica-1322	56	5	absorption	absorption	NOUN
ecletica-1322	56	6	,	,	PUNCT
ecletica-1322	56	7	distribution	distribution	NOUN
ecletica-1322	56	8	,	,	PUNCT
ecletica-1322	56	9	metabolism	metabolism	NOUN
ecletica-1322	56	10	,	,	PUNCT
ecletica-1322	56	11	excretion	excretion	NOUN
ecletica-1322	56	12	and	and	CCONJ
ecletica-1322	56	13	toxicology	toxicology	NOUN
ecletica-1322	56	14	of	of	ADP
ecletica-1322	56	15	a	a	DET
ecletica-1322	56	16	substance	substance	NOUN
ecletica-1322	56	17	in	in	ADP
ecletica-1322	56	18	and	and	CCONJ
ecletica-1322	56	19	through	through	ADP
ecletica-1322	56	20	the	the	DET
ecletica-1322	56	21	human	human	ADJ
ecletica-1322	56	22	body	body	NOUN
ecletica-1322	56	23	are	be	AUX
ecletica-1322	56	24	dealt	deal	VERB
ecletica-1322	56	25	with	with	ADP
ecletica-1322	56	26	by	by	ADP
ecletica-1322	56	27	admet	admet	PROPN
ecletica-1322	56	28	characteristics	characteristics	PROPN
ecletica-1322	56	29	(	(	PUNCT
ecletica-1322	56	30	balani	balani	PROPN
ecletica-1322	56	31	et	et	PROPN
ecletica-1322	56	32	al	al	PROPN
ecletica-1322	56	33	.	.	PROPN
ecletica-1322	56	34	,	,	PUNCT
ecletica-1322	56	35	2005	2005	NUM
ecletica-1322	56	36	)	)	PUNCT
ecletica-1322	56	37	.	.	PUNCT
ecletica-1322	57	1	the	the	DET
ecletica-1322	57	2	modeled	model	VERB
ecletica-1322	57	3	ligands	ligand	NOUN
ecletica-1322	57	4	(	(	PUNCT
ecletica-1322	57	5	a	a	DET
ecletica-1322	57	6	–	–	PUNCT
ecletica-1322	57	7	f	f	X
ecletica-1322	57	8	)	)	PUNCT
ecletica-1322	57	9	were	be	AUX
ecletica-1322	57	10	evaluated	evaluate	VERB
ecletica-1322	57	11	for	for	ADP
ecletica-1322	57	12	their	their	PRON
ecletica-1322	57	13	adme	adme	NOUN
ecletica-1322	57	14	properties	property	NOUN
ecletica-1322	57	15	using	use	VERB
ecletica-1322	57	16	swissadme	swissadme	NOUN
ecletica-1322	57	17	software	software	NOUN
ecletica-1322	57	18	(	(	PUNCT
ecletica-1322	57	19	daina	daina	PROPN
ecletica-1322	57	20	et	et	PROPN
ecletica-1322	57	21	al	al	PROPN
ecletica-1322	57	22	.	.	PROPN
ecletica-1322	57	23	,	,	PUNCT
ecletica-1322	57	24	2017	2017	NUM
ecletica-1322	57	25	;	;	PUNCT
ecletica-1322	57	26	oyebamiji	oyebamiji	NOUN
ecletica-1322	57	27	et	et	PROPN
ecletica-1322	57	28	al	al	PROPN
ecletica-1322	57	29	.	.	PROPN
ecletica-1322	57	30	,	,	PUNCT
ecletica-1322	57	31	2022	2022	NUM
ecletica-1322	57	32	)	)	PUNCT
ecletica-1322	57	33	for	for	ADP
ecletica-1322	57	34	accessing	access	VERB
ecletica-1322	57	35	their	their	PRON
ecletica-1322	57	36	oral	oral	ADJ
ecletica-1322	57	37	-	-	PUNCT
ecletica-1322	57	38	bioavailability	bioavailability	NOUN
ecletica-1322	57	39	and	and	CCONJ
ecletica-1322	57	40	drug	drug	NOUN
ecletica-1322	57	41	-	-	PUNCT
ecletica-1322	57	42	likeness	likeness	NOUN
ecletica-1322	57	43	features	feature	NOUN
ecletica-1322	57	44	.	.	PUNCT
ecletica-1322	58	1	these	these	DET
ecletica-1322	58	2	assist	assist	NOUN
ecletica-1322	58	3	in	in	ADP
ecletica-1322	58	4	studying	study	VERB
ecletica-1322	58	5	the	the	DET
ecletica-1322	58	6	ligands	ligand	NOUN
ecletica-1322	58	7	’	’	PART
ecletica-1322	58	8	pharmacokinetics	pharmacokinetic	NOUN
ecletica-1322	58	9	and	and	CCONJ
ecletica-1322	58	10	pharmacodynamics	pharmacodynamic	NOUN
ecletica-1322	58	11	properties	property	NOUN
ecletica-1322	58	12	(	(	PUNCT
ecletica-1322	58	13	iwaloye	iwaloye	NOUN
ecletica-1322	58	14	et	et	PROPN
ecletica-1322	58	15	al	al	PROPN
ecletica-1322	58	16	.	.	PROPN
ecletica-1322	58	17	,	,	PUNCT
ecletica-1322	58	18	2021	2021	NUM
ecletica-1322	58	19	)	)	PUNCT
ecletica-1322	58	20	.	.	PUNCT
ecletica-1322	59	1	molecular	molecular	ADJ
ecletica-1322	59	2	weight	weight	NOUN
ecletica-1322	59	3	,	,	PUNCT
ecletica-1322	59	4	hydrogen	hydrogen	NOUN
ecletica-1322	59	5	bond	bond	NOUN
ecletica-1322	59	6	donor	donor	NOUN
ecletica-1322	59	7	(	(	PUNCT
ecletica-1322	59	8	hbd	hbd	PROPN
ecletica-1322	59	9	)	)	PUNCT
ecletica-1322	59	10	,	,	PUNCT
ecletica-1322	59	11	hydrogen	hydrogen	NOUN
ecletica-1322	59	12	bond	bond	NOUN
ecletica-1322	59	13	acceptor	acceptor	NOUN
ecletica-1322	59	14	(	(	PUNCT
ecletica-1322	59	15	hba	hba	NOUN
ecletica-1322	59	16	)	)	PUNCT
ecletica-1322	59	17	,	,	PUNCT
ecletica-1322	59	18	blood	blood	NOUN
ecletica-1322	59	19	–	–	PUNCT
ecletica-1322	59	20	brain	brain	NOUN
ecletica-1322	59	21	barrier	barrier	NOUN
ecletica-1322	59	22	(	(	PUNCT
ecletica-1322	59	23	bbb	bbb	PROPN
ecletica-1322	59	24	)	)	PUNCT
ecletica-1322	59	25	,	,	PUNCT
ecletica-1322	59	26	human	human	ADJ
ecletica-1322	59	27	intestinal	intestinal	ADJ
ecletica-1322	59	28	absorption	absorption	NOUN
ecletica-1322	59	29	(	(	PUNCT
ecletica-1322	59	30	hia	hia	PROPN
ecletica-1322	59	31	)	)	PUNCT
ecletica-1322	59	32	are	be	AUX
ecletica-1322	59	33	all	all	PRON
ecletica-1322	59	34	predicted	predict	VERB
ecletica-1322	59	35	significant	significant	ADJ
ecletica-1322	59	36	adme	adme	NOUN
ecletica-1322	59	37	properties	property	NOUN
ecletica-1322	59	38	.	.	PUNCT
ecletica-1322	60	1	https://revista.iq.unesp.br/index.php/ecletica	https://revista.iq.unesp.br/index.php/ecletica	PROPN
ecletica-1322	60	2	https://doi.org/10.26850/1678-4618eqj.v47.4.2022.p27-36	https://doi.org/10.26850/1678-4618eqj.v47.4.2022.p27-36	NOUN
ecletica-1322	60	3	original	original	ADJ
ecletica-1322	60	4	article	article	NOUN
ecletica-1322	60	5	revista.iq.unesp.br	revista.iq.unesp.br	PROPN
ecletica-1322	60	6	31	31	NUM
ecletica-1322	60	7	eclética	eclética	PROPN
ecletica-1322	60	8	química	química	PROPN
ecletica-1322	60	9	journal	journal	PROPN
ecletica-1322	60	10	,	,	PUNCT
ecletica-1322	60	11	vol	vol	NOUN
ecletica-1322	60	12	.	.	PROPN
ecletica-1322	60	13	47	47	NUM
ecletica-1322	60	14	,	,	PUNCT
ecletica-1322	60	15	n.	n.	NOUN
ecletica-1322	60	16	4	4	NUM
ecletica-1322	60	17	,	,	PUNCT
ecletica-1322	60	18	2022	2022	NUM
ecletica-1322	60	19	,	,	PUNCT
ecletica-1322	60	20	27	27	NUM
ecletica-1322	60	21	-	-	SYM
ecletica-1322	60	22	36	36	NUM
ecletica-1322	60	23	issn	issn	NOUN
ecletica-1322	60	24	:	:	PUNCT
ecletica-1322	60	25	1678	1678	NUM
ecletica-1322	60	26	-	-	SYM
ecletica-1322	60	27	4618	4618	NUM
ecletica-1322	60	28	doi	doi	NOUN
ecletica-1322	60	29	:	:	PUNCT
ecletica-1322	60	30	10.26850/1678	10.26850/1678	NUM
ecletica-1322	60	31	-	-	SYM
ecletica-1322	60	32	4618eqj.v47.4.2022.p27	4618eqj.v47.4.2022.p27	NUM
ecletica-1322	60	33	-	-	PUNCT
ecletica-1322	60	34	36	36	NUM
ecletica-1322	60	35	figure	figure	NOUN
ecletica-1322	60	36	4	4	NUM
ecletica-1322	60	37	.	.	PUNCT
ecletica-1322	60	38	2d	2d	NUM
ecletica-1322	60	39	structure	structure	NOUN
ecletica-1322	60	40	of	of	ADP
ecletica-1322	60	41	interaction	interaction	NOUN
ecletica-1322	60	42	between	between	ADP
ecletica-1322	60	43	compound	compound	NOUN
ecletica-1322	60	44	(	(	PUNCT
ecletica-1322	60	45	a	a	DET
ecletica-1322	60	46	–	–	PUNCT
ecletica-1322	60	47	f	f	NOUN
ecletica-1322	60	48	)	)	PUNCT
ecletica-1322	60	49	and	and	CCONJ
ecletica-1322	60	50	nitroreductase	nitroreductase	VERB
ecletica-1322	60	51	rdxa	rdxa	NOUN
ecletica-1322	60	52	protein	protein	NOUN
ecletica-1322	60	53	(	(	PUNCT
ecletica-1322	60	54	pdb	pdb	PROPN
ecletica-1322	60	55	i	i	PROPN
ecletica-1322	60	56	d	d	PROPN
ecletica-1322	60	57	:	:	PUNCT
ecletica-1322	60	58	3qdl	3qdl	NUM
ecletica-1322	60	59	)	)	PUNCT
ecletica-1322	60	60	.	.	PUNCT
ecletica-1322	61	1	3	3	X
ecletica-1322	61	2	.	.	NOUN
ecletica-1322	61	3	results	result	NOUN
ecletica-1322	61	4	and	and	CCONJ
ecletica-1322	61	5	discussion	discussion	NOUN
ecletica-1322	61	6	3.1	3.1	NUM
ecletica-1322	61	7	calculated	calculate	VERB
ecletica-1322	61	8	descriptors	descriptor	NOUN
ecletica-1322	61	9	the	the	DET
ecletica-1322	61	10	frontier	frontier	NOUN
ecletica-1322	61	11	orbital	orbital	ADJ
ecletica-1322	61	12	electron	electron	NOUN
ecletica-1322	61	13	densities	density	NOUN
ecletica-1322	61	14	of	of	ADP
ecletica-1322	61	15	atoms	atom	NOUN
ecletica-1322	61	16	in	in	ADP
ecletica-1322	61	17	a	a	DET
ecletica-1322	61	18	molecule	molecule	NOUN
ecletica-1322	61	19	can	can	AUX
ecletica-1322	61	20	be	be	AUX
ecletica-1322	61	21	used	use	VERB
ecletica-1322	61	22	to	to	PART
ecletica-1322	61	23	analyze	analyze	VERB
ecletica-1322	61	24	the	the	DET
ecletica-1322	61	25	electron	electron	NOUN
ecletica-1322	61	26	donor	donor	NOUN
ecletica-1322	61	27	acceptor	acceptor	NOUN
ecletica-1322	61	28	interaction	interaction	NOUN
ecletica-1322	61	29	(	(	PUNCT
ecletica-1322	61	30	akintelu	akintelu	ADV
ecletica-1322	61	31	et	et	PROPN
ecletica-1322	61	32	al	al	PROPN
ecletica-1322	61	33	.	.	PROPN
ecletica-1322	61	34	,	,	PUNCT
ecletica-1322	61	35	2021	2021	NUM
ecletica-1322	61	36	)	)	PUNCT
ecletica-1322	61	37	.	.	PUNCT
ecletica-1322	62	1	the	the	DET
ecletica-1322	62	2	2d	2d	PROPN
ecletica-1322	62	3	structures	structure	NOUN
ecletica-1322	62	4	for	for	ADP
ecletica-1322	62	5	the	the	DET
ecletica-1322	62	6	studied	study	VERB
ecletica-1322	62	7	compounds	compound	NOUN
ecletica-1322	62	8	are	be	AUX
ecletica-1322	62	9	as	as	SCONJ
ecletica-1322	62	10	shown	show	VERB
ecletica-1322	62	11	on	on	ADP
ecletica-1322	62	12	tab	tab	NOUN
ecletica-1322	62	13	.	.	PUNCT
ecletica-1322	63	1	1	1	X
ecletica-1322	63	2	.	.	X
ecletica-1322	64	1	the	the	DET
ecletica-1322	64	2	frontier	frontier	NOUN
ecletica-1322	64	3	molecular	molecular	ADJ
ecletica-1322	64	4	orbital	orbital	ADJ
ecletica-1322	64	5	energies	energy	NOUN
ecletica-1322	64	6	(	(	PUNCT
ecletica-1322	64	7	ehomo	ehomo	ADJ
ecletica-1322	64	8	and	and	CCONJ
ecletica-1322	64	9	elumo	elumo	ADJ
ecletica-1322	64	10	)	)	PUNCT
ecletica-1322	64	11	are	be	AUX
ecletica-1322	64	12	used	use	VERB
ecletica-1322	64	13	to	to	PART
ecletica-1322	64	14	determine	determine	VERB
ecletica-1322	64	15	how	how	SCONJ
ecletica-1322	64	16	a	a	DET
ecletica-1322	64	17	molecule	molecule	NOUN
ecletica-1322	64	18	interacts	interact	VERB
ecletica-1322	64	19	with	with	ADP
ecletica-1322	64	20	the	the	DET
ecletica-1322	64	21	other	other	ADJ
ecletica-1322	64	22	species	specie	NOUN
ecletica-1322	64	23	.	.	PUNCT
ecletica-1322	65	1	the	the	DET
ecletica-1322	65	2	ehomo	ehomo	ADJ
ecletica-1322	65	3	orbital	orbital	ADJ
ecletica-1322	65	4	energy	energy	NOUN
ecletica-1322	65	5	donates	donate	VERB
ecletica-1322	65	6	electron	electron	NOUN
ecletica-1322	65	7	,	,	PUNCT
ecletica-1322	65	8	since	since	SCONJ
ecletica-1322	65	9	it	it	PRON
ecletica-1322	65	10	is	be	AUX
ecletica-1322	65	11	the	the	DET
ecletica-1322	65	12	outermost	outermost	ADJ
ecletica-1322	65	13	(	(	PUNCT
ecletica-1322	65	14	highest	high	ADJ
ecletica-1322	65	15	energy	energy	NOUN
ecletica-1322	65	16	)	)	PUNCT
ecletica-1322	65	17	orbital	orbital	ADJ
ecletica-1322	65	18	containing	contain	VERB
ecletica-1322	65	19	electrons	electron	NOUN
ecletica-1322	65	20	.	.	PUNCT
ecletica-1322	66	1	in	in	ADP
ecletica-1322	66	2	contrast	contrast	NOUN
ecletica-1322	66	3	,	,	PUNCT
ecletica-1322	66	4	the	the	DET
ecletica-1322	66	5	elumo	elumo	ADJ
ecletica-1322	66	6	orbital	orbital	NOUN
ecletica-1322	66	7	accepts	accept	VERB
ecletica-1322	66	8	electrons	electron	NOUN
ecletica-1322	66	9	since	since	SCONJ
ecletica-1322	66	10	it	it	PRON
ecletica-1322	66	11	is	be	AUX
ecletica-1322	66	12	the	the	DET
ecletica-1322	66	13	innermost	innermost	NOUN
ecletica-1322	66	14	(	(	PUNCT
ecletica-1322	66	15	lowest	low	ADJ
ecletica-1322	66	16	energy	energy	NOUN
ecletica-1322	66	17	)	)	PUNCT
ecletica-1322	66	18	orbital	orbital	NOUN
ecletica-1322	66	19	that	that	PRON
ecletica-1322	66	20	can	can	AUX
ecletica-1322	66	21	accept	accept	VERB
ecletica-1322	66	22	electrons	electron	NOUN
ecletica-1322	66	23	(	(	PUNCT
ecletica-1322	66	24	raj	raj	NOUN
ecletica-1322	66	25	et	et	PROPN
ecletica-1322	66	26	al	al	PROPN
ecletica-1322	66	27	.	.	PROPN
ecletica-1322	66	28	,	,	PUNCT
ecletica-1322	66	29	2015	2015	NUM
ecletica-1322	66	30	)	)	PUNCT
ecletica-1322	66	31	.	.	PUNCT
ecletica-1322	67	1	according	accord	VERB
ecletica-1322	67	2	to	to	ADP
ecletica-1322	67	3	the	the	DET
ecletica-1322	67	4	frontier	frontier	NOUN
ecletica-1322	67	5	molecular	molecular	ADJ
ecletica-1322	67	6	orbital	orbital	ADJ
ecletica-1322	67	7	theory	theory	NOUN
ecletica-1322	67	8	,	,	PUNCT
ecletica-1322	67	9	the	the	DET
ecletica-1322	67	10	interaction	interaction	NOUN
ecletica-1322	67	11	between	between	ADP
ecletica-1322	67	12	the	the	DET
ecletica-1322	67	13	homo	homo	NOUN
ecletica-1322	67	14	and	and	CCONJ
ecletica-1322	67	15	lumo	lumo	NOUN
ecletica-1322	67	16	of	of	ADP
ecletica-1322	67	17	reactants	reactant	NOUN
ecletica-1322	67	18	formed	form	VERB
ecletica-1322	67	19	the	the	DET
ecletica-1322	67	20	transition	transition	NOUN
ecletica-1322	67	21	state	state	NOUN
ecletica-1322	67	22	.	.	PUNCT
ecletica-1322	68	1	the	the	DET
ecletica-1322	68	2	ehomo	ehomo	NOUN
ecletica-1322	68	3	and	and	CCONJ
ecletica-1322	68	4	elumo	elumo	NOUN
ecletica-1322	68	5	are	be	AUX
ecletica-1322	68	6	directly	directly	ADV
ecletica-1322	68	7	related	relate	VERB
ecletica-1322	68	8	to	to	ADP
ecletica-1322	68	9	the	the	DET
ecletica-1322	68	10	ip	ip	NOUN
ecletica-1322	68	11	and	and	CCONJ
ecletica-1322	68	12	ea	ea	NOUN
ecletica-1322	68	13	respectively	respectively	ADV
ecletica-1322	68	14	(	(	PUNCT
ecletica-1322	68	15	eqs	eqs	X
ecletica-1322	68	16	.	.	PROPN
ecletica-1322	68	17	1	1	NUM
ecletica-1322	68	18	and	and	CCONJ
ecletica-1322	68	19	2	2	NUM
ecletica-1322	68	20	)	)	PUNCT
ecletica-1322	68	21	.	.	PUNCT
ecletica-1322	69	1	higher	high	ADJ
ecletica-1322	69	2	ehomo	ehomo	NOUN
ecletica-1322	69	3	signify	signify	VERB
ecletica-1322	69	4	that	that	SCONJ
ecletica-1322	69	5	the	the	DET
ecletica-1322	69	6	compound	compound	NOUN
ecletica-1322	69	7	has	have	VERB
ecletica-1322	69	8	stronger	strong	ADJ
ecletica-1322	69	9	ability	ability	NOUN
ecletica-1322	69	10	to	to	PART
ecletica-1322	69	11	donate	donate	VERB
ecletica-1322	69	12	electron(s	electron(s	PROPN
ecletica-1322	69	13	)	)	PUNCT
ecletica-1322	69	14	to	to	ADP
ecletica-1322	69	15	the	the	DET
ecletica-1322	69	16	neighboring	neighboring	NOUN
ecletica-1322	69	17	compound	compound	NOUN
ecletica-1322	69	18	,	,	PUNCT
ecletica-1322	69	19	the	the	DET
ecletica-1322	69	20	better	well	ADJ
ecletica-1322	69	21	ability	ability	NOUN
ecletica-1322	69	22	of	of	ADP
ecletica-1322	69	23	its	its	PRON
ecletica-1322	69	24	drug	drug	NOUN
ecletica-1322	69	25	-	-	PUNCT
ecletica-1322	69	26	likeness	likeness	NOUN
ecletica-1322	69	27	properties	property	NOUN
ecletica-1322	69	28	,	,	PUNCT
ecletica-1322	69	29	as	as	ADV
ecletica-1322	69	30	well	well	ADV
ecletica-1322	69	31	as	as	ADP
ecletica-1322	69	32	the	the	DET
ecletica-1322	69	33	ability	ability	NOUN
ecletica-1322	69	34	of	of	ADP
ecletica-1322	69	35	such	such	ADJ
ecletica-1322	69	36	compound	compound	NOUN
ecletica-1322	69	37	to	to	PART
ecletica-1322	69	38	inhibit	inhibit	VERB
ecletica-1322	69	39	receptor	receptor	NOUN
ecletica-1322	69	40	(	(	PUNCT
ecletica-1322	69	41	gao	gao	PROPN
ecletica-1322	69	42	et	et	PROPN
ecletica-1322	69	43	al	al	PROPN
ecletica-1322	69	44	.	.	PROPN
ecletica-1322	69	45	,	,	PUNCT
ecletica-1322	69	46	2010	2010	NUM
ecletica-1322	69	47	)	)	PUNCT
ecletica-1322	69	48	.	.	PUNCT
ecletica-1322	70	1	the	the	DET
ecletica-1322	70	2	band	band	NOUN
ecletica-1322	70	3	gap	gap	NOUN
ecletica-1322	70	4	(	(	PUNCT
ecletica-1322	70	5	eg	eg	NOUN
ecletica-1322	70	6	/	/	SYM
ecletica-1322	70	7	ehomo	ehomo	ADJ
ecletica-1322	70	8	–	–	PUNCT
ecletica-1322	70	9	elumo	elumo	ADJ
ecletica-1322	70	10	)	)	PUNCT
ecletica-1322	70	11	is	be	AUX
ecletica-1322	70	12	also	also	ADV
ecletica-1322	70	13	an	an	DET
ecletica-1322	70	14	important	important	ADJ
ecletica-1322	70	15	parameter	parameter	NOUN
ecletica-1322	70	16	that	that	PRON
ecletica-1322	70	17	reflects	reflect	VERB
ecletica-1322	70	18	the	the	DET
ecletica-1322	70	19	chemical	chemical	ADJ
ecletica-1322	70	20	activity	activity	NOUN
ecletica-1322	70	21	of	of	ADP
ecletica-1322	70	22	the	the	DET
ecletica-1322	70	23	molecules	molecule	NOUN
ecletica-1322	70	24	.	.	PUNCT
ecletica-1322	71	1	the	the	DET
ecletica-1322	71	2	eg	eg	NOUN
ecletica-1322	71	3	and	and	CCONJ
ecletica-1322	71	4	associated	associate	VERB
ecletica-1322	71	5	molecular/	molecular/	NUM
ecletica-1322	71	6	physicochemical	physicochemical	ADJ
ecletica-1322	71	7	properties	property	NOUN
ecletica-1322	71	8	are	be	AUX
ecletica-1322	71	9	as	as	ADP
ecletica-1322	71	10	presented	present	VERB
ecletica-1322	71	11	in	in	ADP
ecletica-1322	71	12	tab	tab	NOUN
ecletica-1322	71	13	.	.	PUNCT
ecletica-1322	72	1	2	2	NUM
ecletica-1322	72	2	.	.	X
ecletica-1322	72	3	more	more	ADV
ecletica-1322	72	4	so	so	ADV
ecletica-1322	72	5	,	,	PUNCT
ecletica-1322	72	6	the	the	DET
ecletica-1322	72	7	homo	homo	NOUN
ecletica-1322	72	8	π	π	NOUN
ecletica-1322	72	9	-	-	PUNCT
ecletica-1322	72	10	electrons	electron	NOUN
ecletica-1322	72	11	are	be	AUX
ecletica-1322	72	12	delocalized	delocalize	VERB
ecletica-1322	72	13	on	on	ADP
ecletica-1322	72	14	the	the	DET
ecletica-1322	72	15	5	5	NUM
ecletica-1322	72	16	-	-	PUNCT
ecletica-1322	72	17	nitroimidazole	nitroimidazole	NOUN
ecletica-1322	72	18	ring	ring	NOUN
ecletica-1322	72	19	in	in	ADP
ecletica-1322	72	20	compounds	compound	NOUN
ecletica-1322	72	21	a	a	DET
ecletica-1322	72	22	,	,	PUNCT
ecletica-1322	72	23	b	b	NOUN
ecletica-1322	72	24	,	,	PUNCT
ecletica-1322	72	25	d	d	NOUN
ecletica-1322	72	26	and	and	CCONJ
ecletica-1322	72	27	e	e	NOUN
ecletica-1322	72	28	,	,	PUNCT
ecletica-1322	72	29	delocalized	delocalize	VERB
ecletica-1322	72	30	on	on	ADP
ecletica-1322	72	31	the	the	DET
ecletica-1322	72	32	entire	entire	ADJ
ecletica-1322	72	33	molecules	molecule	NOUN
ecletica-1322	72	34	in	in	ADP
ecletica-1322	72	35	compound	compound	NOUN
ecletica-1322	72	36	f	f	NOUN
ecletica-1322	72	37	,	,	PUNCT
ecletica-1322	72	38	but	but	CCONJ
ecletica-1322	72	39	localized	localize	VERB
ecletica-1322	72	40	on	on	ADP
ecletica-1322	72	41	thiophenylethyl	thiophenylethyl	PROPN
ecletica-1322	72	42	substituent	substituent	NOUN
ecletica-1322	72	43	of	of	ADP
ecletica-1322	72	44	compound	compound	NOUN
ecletica-1322	72	45	c.	c.	PROPN
ecletica-1322	72	46	however	however	ADV
ecletica-1322	72	47	,	,	PUNCT
ecletica-1322	72	48	the	the	DET
ecletica-1322	72	49	lumo	lumo	ADJ
ecletica-1322	72	50	π	π	NOUN
ecletica-1322	72	51	-	-	NOUN
ecletica-1322	72	52	electrons	electron	NOUN
ecletica-1322	72	53	are	be	AUX
ecletica-1322	72	54	more	more	ADV
ecletica-1322	72	55	localized	localized	ADJ
ecletica-1322	72	56	on	on	ADP
ecletica-1322	72	57	the	the	DET
ecletica-1322	72	58	nitro	nitro	NOUN
ecletica-1322	72	59	(	(	PUNCT
ecletica-1322	72	60	no2	no2	NOUN
ecletica-1322	72	61	)	)	PUNCT
ecletica-1322	72	62	group	group	NOUN
ecletica-1322	72	63	substituent	substituent	NOUN
ecletica-1322	72	64	of	of	ADP
ecletica-1322	72	65	the	the	DET
ecletica-1322	72	66	nitroimidazole	nitroimidazole	PROPN
ecletica-1322	72	67	ring	ring	NOUN
ecletica-1322	72	68	in	in	ADP
ecletica-1322	72	69	compounds	compound	NOUN
ecletica-1322	72	70	a	a	PRON
ecletica-1322	72	71	,	,	PUNCT
ecletica-1322	72	72	b	b	NOUN
ecletica-1322	72	73	,	,	PUNCT
ecletica-1322	72	74	d	d	NOUN
ecletica-1322	72	75	,	,	PUNCT
ecletica-1322	72	76	e	e	NOUN
ecletica-1322	72	77	and	and	CCONJ
ecletica-1322	72	78	f	f	X
ecletica-1322	72	79	,	,	PUNCT
ecletica-1322	72	80	but	but	CCONJ
ecletica-1322	72	81	are	be	AUX
ecletica-1322	72	82	more	more	ADV
ecletica-1322	72	83	localized	localized	ADJ
ecletica-1322	72	84	on	on	ADP
ecletica-1322	72	85	the	the	DET
ecletica-1322	72	86	5	5	NUM
ecletica-1322	72	87	-	-	PUNCT
ecletica-1322	72	88	nitroimidazole	nitroimidazole	NOUN
ecletica-1322	72	89	ring	ring	NOUN
ecletica-1322	72	90	in	in	ADP
ecletica-1322	72	91	compound	compound	NOUN
ecletica-1322	72	92	c.	c.	PROPN
ecletica-1322	72	93	this	this	PRON
ecletica-1322	72	94	attests	attest	VERB
ecletica-1322	72	95	to	to	ADP
ecletica-1322	72	96	studied	study	VERB
ecletica-1322	72	97	compounds	compound	NOUN
ecletica-1322	72	98	’	'	PUNCT
ecletica-1322	72	99	intramolecular	intramolecular	ADJ
ecletica-1322	72	100	charge	charge	NOUN
ecletica-1322	72	101	transfer	transfer	NOUN
ecletica-1322	72	102	characteristic	characteristic	ADJ
ecletica-1322	72	103	properties	property	NOUN
ecletica-1322	72	104	(	(	PUNCT
ecletica-1322	72	105	kulhánek	kulhánek	ADV
ecletica-1322	72	106	et	et	PROPN
ecletica-1322	72	107	al	al	PROPN
ecletica-1322	72	108	.	.	PROPN
ecletica-1322	72	109	,	,	PUNCT
ecletica-1322	72	110	2012	2012	NUM
ecletica-1322	72	111	)	)	PUNCT
ecletica-1322	72	112	.	.	PUNCT
ecletica-1322	73	1	the	the	DET
ecletica-1322	73	2	lowest	low	ADJ
ecletica-1322	73	3	and	and	CCONJ
ecletica-1322	73	4	highest	high	ADJ
ecletica-1322	73	5	eg	eg	NOUN
ecletica-1322	73	6	values	value	NOUN
ecletica-1322	73	7	were	be	AUX
ecletica-1322	73	8	recorded	record	VERB
ecletica-1322	73	9	for	for	ADP
ecletica-1322	73	10	compound	compound	NOUN
ecletica-1322	73	11	c	c	PROPN
ecletica-1322	73	12	(	(	PUNCT
ecletica-1322	73	13	3.94	3.94	NUM
ecletica-1322	73	14	ev	ev	NOUN
ecletica-1322	73	15	)	)	PUNCT
ecletica-1322	73	16	and	and	CCONJ
ecletica-1322	73	17	e	e	X
ecletica-1322	73	18	(	(	PUNCT
ecletica-1322	73	19	4.63	4.63	NUM
ecletica-1322	73	20	ev	ev	NOUN
ecletica-1322	73	21	)	)	PUNCT
ecletica-1322	73	22	respectively	respectively	ADV
ecletica-1322	73	23	;	;	PUNCT
ecletica-1322	73	24	a	a	DET
ecletica-1322	73	25	strong	strong	ADJ
ecletica-1322	73	26	indication	indication	NOUN
ecletica-1322	73	27	of	of	ADP
ecletica-1322	73	28	highest	high	ADJ
ecletica-1322	73	29	distribution	distribution	NOUN
ecletica-1322	73	30	of	of	ADP
ecletica-1322	73	31	charges	charge	NOUN
ecletica-1322	73	32	,	,	PUNCT
ecletica-1322	73	33	and	and	CCONJ
ecletica-1322	73	34	hence	hence	ADV
ecletica-1322	73	35	,	,	PUNCT
ecletica-1322	73	36	the	the	DET
ecletica-1322	73	37	probability	probability	NOUN
ecletica-1322	73	38	of	of	ADP
ecletica-1322	73	39	higher	high	ADJ
ecletica-1322	73	40	chemical	chemical	NOUN
ecletica-1322	73	41	activity	activity	NOUN
ecletica-1322	73	42	of	of	ADP
ecletica-1322	73	43	compound	compound	NOUN
ecletica-1322	73	44	c	c	NOUN
ecletica-1322	73	45	(	(	PUNCT
ecletica-1322	73	46	r	r	NOUN
ecletica-1322	73	47	=	=	SYM
ecletica-1322	73	48	sph3	sph3	NOUN
ecletica-1322	73	49	)	)	PUNCT
ecletica-1322	73	50	compared	compare	VERB
ecletica-1322	73	51	with	with	ADP
ecletica-1322	73	52	the	the	DET
ecletica-1322	73	53	other	other	ADJ
ecletica-1322	73	54	compounds	compound	NOUN
ecletica-1322	73	55	(	(	PUNCT
ecletica-1322	73	56	oyebamiji	oyebamiji	NOUN
ecletica-1322	73	57	et	et	PROPN
ecletica-1322	73	58	al	al	PROPN
ecletica-1322	73	59	.	.	PROPN
ecletica-1322	73	60	,	,	PUNCT
ecletica-1322	73	61	2021a	2021a	NUM
ecletica-1322	73	62	)	)	PUNCT
ecletica-1322	73	63	.	.	PUNCT
ecletica-1322	74	1	𝐼𝑃	𝐼𝑃	PROPN
ecletica-1322	74	2	=	=	SYM
ecletica-1322	74	3	𝐸𝐻𝑂𝑀𝑂	𝐸𝐻𝑂𝑀𝑂	PROPN
ecletica-1322	74	4	(	(	PUNCT
ecletica-1322	74	5	1	1	X
ecletica-1322	74	6	)	)	PUNCT
ecletica-1322	74	7	𝐸𝐴	𝐸𝐴	NOUN
ecletica-1322	74	8	=	=	SYM
ecletica-1322	74	9	𝐸𝐿𝑈𝑀𝑂	𝐸𝐿𝑈𝑀𝑂	NOUN
ecletica-1322	74	10	(	(	PUNCT
ecletica-1322	74	11	2	2	X
ecletica-1322	74	12	)	)	PUNCT
ecletica-1322	74	13	the	the	DET
ecletica-1322	74	14	partition	partition	NOUN
ecletica-1322	74	15	coefficient	coefficient	NOUN
ecletica-1322	74	16	(	(	PUNCT
ecletica-1322	74	17	lipophilicity	lipophilicity	NOUN
ecletica-1322	74	18	/	/	SYM
ecletica-1322	74	19	log	log	NOUN
ecletica-1322	74	20	p	p	NOUN
ecletica-1322	74	21	)	)	PUNCT
ecletica-1322	74	22	plays	play	VERB
ecletica-1322	74	23	important	important	ADJ
ecletica-1322	74	24	roles	role	NOUN
ecletica-1322	74	25	in	in	ADP
ecletica-1322	74	26	drugs	drug	NOUN
ecletica-1322	74	27	design	design	NOUN
ecletica-1322	74	28	(	(	PUNCT
ecletica-1322	74	29	méndez	méndez	NOUN
ecletica-1322	74	30	-	-	PUNCT
ecletica-1322	74	31	lucio	lucio	PROPN
ecletica-1322	74	32	et	et	PROPN
ecletica-1322	74	33	al	al	PROPN
ecletica-1322	74	34	.	.	PROPN
ecletica-1322	74	35	,	,	PUNCT
ecletica-1322	74	36	2017	2017	NUM
ecletica-1322	74	37	)	)	PUNCT
ecletica-1322	74	38	.	.	PUNCT
ecletica-1322	75	1	it	it	PRON
ecletica-1322	75	2	has	have	AUX
ecletica-1322	75	3	been	be	AUX
ecletica-1322	75	4	described	describe	VERB
ecletica-1322	75	5	as	as	ADP
ecletica-1322	75	6	the	the	DET
ecletica-1322	75	7	main	main	ADJ
ecletica-1322	75	8	physicochemical	physicochemical	ADJ
ecletica-1322	75	9	determinant	determinant	NOUN
ecletica-1322	75	10	that	that	PRON
ecletica-1322	75	11	influences	influence	VERB
ecletica-1322	75	12	the	the	DET
ecletica-1322	75	13	bioavailability	bioavailability	NOUN
ecletica-1322	75	14	,	,	PUNCT
ecletica-1322	75	15	permeability	permeability	NOUN
ecletica-1322	75	16	,	,	PUNCT
ecletica-1322	75	17	and	and	CCONJ
ecletica-1322	75	18	penetrability	penetrability	NOUN
ecletica-1322	75	19	of	of	ADP
ecletica-1322	75	20	pharmacophore	pharmacophore	NOUN
ecletica-1322	75	21	in	in	ADP
ecletica-1322	75	22	biological	biological	ADJ
ecletica-1322	75	23	membranes	membrane	NOUN
ecletica-1322	75	24	,	,	PUNCT
ecletica-1322	75	25	and	and	CCONJ
ecletica-1322	75	26	toxicity	toxicity	NOUN
ecletica-1322	75	27	of	of	ADP
ecletica-1322	75	28	the	the	DET
ecletica-1322	75	29	compounds	compound	NOUN
ecletica-1322	75	30	.	.	PUNCT
ecletica-1322	76	1	their	their	PRON
ecletica-1322	76	2	values	value	NOUN
ecletica-1322	76	3	are	be	AUX
ecletica-1322	76	4	therefore	therefore	ADV
ecletica-1322	76	5	used	use	VERB
ecletica-1322	76	6	as	as	ADP
ecletica-1322	76	7	determinants	determinant	NOUN
ecletica-1322	76	8	in	in	ADP
ecletica-1322	76	9	some	some	DET
ecletica-1322	76	10	industrial	industrial	ADJ
ecletica-1322	76	11	processes	process	NOUN
ecletica-1322	76	12	,	,	PUNCT
ecletica-1322	76	13	such	such	ADJ
ecletica-1322	76	14	as	as	ADP
ecletica-1322	76	15	agricultural	agricultural	ADJ
ecletica-1322	76	16	chemistry	chemistry	NOUN
ecletica-1322	76	17	,	,	PUNCT
ecletica-1322	76	18	drug	drug	NOUN
ecletica-1322	76	19	formulation	formulation	NOUN
ecletica-1322	76	20	and	and	CCONJ
ecletica-1322	76	21	flavoring	flavoring	NOUN
ecletica-1322	76	22	of	of	ADP
ecletica-1322	76	23	finished	finished	ADJ
ecletica-1322	76	24	products	product	NOUN
ecletica-1322	76	25	(	(	PUNCT
ecletica-1322	76	26	lipinski	lipinski	PROPN
ecletica-1322	76	27	et	et	PROPN
ecletica-1322	76	28	al	al	PROPN
ecletica-1322	76	29	.	.	PROPN
ecletica-1322	76	30	,	,	PUNCT
ecletica-1322	76	31	2020	2020	NUM
ecletica-1322	76	32	;	;	PUNCT
ecletica-1322	76	33	oyebamiji	oyebamiji	NOUN
ecletica-1322	76	34	et	et	PROPN
ecletica-1322	76	35	al	al	PROPN
ecletica-1322	76	36	.	.	PROPN
ecletica-1322	76	37	,	,	PUNCT
ecletica-1322	76	38	2021b	2021b	NUM
ecletica-1322	76	39	)	)	PUNCT
ecletica-1322	76	40	.	.	PUNCT
ecletica-1322	77	1	according	accord	VERB
ecletica-1322	77	2	to	to	ADP
ecletica-1322	77	3	the	the	DET
ecletica-1322	77	4	lipinski	lipinski	PROPN
ecletica-1322	77	5	’s	’s	PART
ecletica-1322	77	6	rule	rule	NOUN
ecletica-1322	77	7	of	of	ADP
ecletica-1322	77	8	5	5	NUM
ecletica-1322	77	9	(	(	PUNCT
ecletica-1322	77	10	mw	mw	ADJ
ecletica-1322	77	11	≤	≤	NUM
ecletica-1322	77	12	500	500	NUM
ecletica-1322	77	13	amu	amu	PROPN
ecletica-1322	77	14	,	,	PUNCT
ecletica-1322	77	15	logp	logp	NOUN
ecletica-1322	77	16	[	[	X
ecletica-1322	77	17	octanolwater	octanolwater	NOUN
ecletica-1322	77	18	partition	partition	NOUN
ecletica-1322	77	19	coefficient	coefficient	NOUN
ecletica-1322	77	20	]	]	PUNCT
ecletica-1322	77	21	≤	≤	NUM
ecletica-1322	77	22	5	5	NUM
ecletica-1322	77	23	,	,	PUNCT
ecletica-1322	77	24	hdb	hdb	NOUN
ecletica-1322	78	1	[	[	X
ecletica-1322	78	2	total	total	ADJ
ecletica-1322	78	3	number	number	NOUN
ecletica-1322	78	4	of	of	ADP
ecletica-1322	78	5	n	n	CCONJ
ecletica-1322	78	6	–	–	PUNCT
ecletica-1322	78	7	h	h	NOUN
ecletica-1322	78	8	and	and	CCONJ
ecletica-1322	78	9	o	o	NOUN
ecletica-1322	78	10	–	–	PUNCT
ecletica-1322	78	11	h	h	NOUN
ecletica-1322	78	12	bonds	bond	NOUN
ecletica-1322	78	13	]	]	PUNCT
ecletica-1322	78	14	≤	≤	NUM
ecletica-1322	78	15	5	5	NUM
ecletica-1322	78	16	and	and	CCONJ
ecletica-1322	78	17	hba	hba	PRON
ecletica-1322	79	1	[	[	X
ecletica-1322	79	2	total	total	ADJ
ecletica-1322	79	3	number	number	NOUN
ecletica-1322	79	4	of	of	ADP
ecletica-1322	79	5	n	n	NUM
ecletica-1322	79	6	and	and	CCONJ
ecletica-1322	79	7	o	o	NOUN
ecletica-1322	79	8	atoms	atom	NOUN
ecletica-1322	79	9	]	]	PUNCT
ecletica-1322	79	10	≤	≤	NUM
ecletica-1322	79	11	10	10	NUM
ecletica-1322	79	12	)	)	PUNCT
ecletica-1322	79	13	(	(	PUNCT
ecletica-1322	79	14	erazua	erazua	NOUN
ecletica-1322	79	15	et	et	PROPN
ecletica-1322	79	16	al	al	PROPN
ecletica-1322	79	17	.	.	PROPN
ecletica-1322	79	18	,	,	PUNCT
ecletica-1322	79	19	2021	2021	NUM
ecletica-1322	79	20	)	)	PUNCT
ecletica-1322	79	21	,	,	PUNCT
ecletica-1322	79	22	problem	problem	NOUN
ecletica-1322	79	23	is	be	AUX
ecletica-1322	79	24	likely	likely	ADJ
ecletica-1322	79	25	to	to	PART
ecletica-1322	79	26	be	be	AUX
ecletica-1322	79	27	encountered	encounter	VERB
ecletica-1322	79	28	in	in	ADP
ecletica-1322	79	29	the	the	DET
ecletica-1322	79	30	oral	oral	ADJ
ecletica-1322	79	31	usage	usage	NOUN
ecletica-1322	79	32	of	of	ADP
ecletica-1322	79	33	this	this	DET
ecletica-1322	79	34	druglike	druglike	NOUN
ecletica-1322	79	35	compound	compound	NOUN
ecletica-1322	79	36	if	if	SCONJ
ecletica-1322	79	37	log	log	NOUN
ecletica-1322	79	38	p	p	NOUN
ecletica-1322	79	39	value	value	NOUN
ecletica-1322	79	40	is	be	AUX
ecletica-1322	79	41	higher	high	ADJ
ecletica-1322	79	42	than	than	ADP
ecletica-1322	79	43	5	5	NUM
ecletica-1322	79	44	(	(	PUNCT
ecletica-1322	79	45	stefaniu	stefaniu	NOUN
ecletica-1322	79	46	and	and	CCONJ
ecletica-1322	79	47	pintilie	pintilie	NOUN
ecletica-1322	79	48	,	,	PUNCT
ecletica-1322	79	49	2018	2018	NUM
ecletica-1322	79	50	)	)	PUNCT
ecletica-1322	79	51	.	.	PUNCT
ecletica-1322	80	1	the	the	DET
ecletica-1322	80	2	log	log	NOUN
ecletica-1322	80	3	p	p	NOUN
ecletica-1322	80	4	for	for	ADP
ecletica-1322	80	5	all	all	DET
ecletica-1322	80	6	the	the	DET
ecletica-1322	80	7	studied	study	VERB
ecletica-1322	80	8	compounds	compound	NOUN
ecletica-1322	80	9	(	(	PUNCT
ecletica-1322	80	10	tab	tab	NOUN
ecletica-1322	80	11	.	.	NOUN
ecletica-1322	80	12	2	2	NUM
ecletica-1322	80	13	)	)	PUNCT
ecletica-1322	80	14	were	be	AUX
ecletica-1322	80	15	within	within	ADP
ecletica-1322	80	16	the	the	DET
ecletica-1322	80	17	acceptable	acceptable	ADJ
ecletica-1322	80	18	range	range	NOUN
ecletica-1322	80	19	,	,	PUNCT
ecletica-1322	80	20	which	which	PRON
ecletica-1322	80	21	therefore	therefore	ADV
ecletica-1322	80	22	showed	show	VERB
ecletica-1322	80	23	that	that	SCONJ
ecletica-1322	80	24	the	the	DET
ecletica-1322	80	25	compounds	compound	NOUN
ecletica-1322	80	26	can	can	AUX
ecletica-1322	80	27	be	be	AUX
ecletica-1322	80	28	taken	take	VERB
ecletica-1322	80	29	https://revista.iq.unesp.br/index.php/ecletica	https://revista.iq.unesp.br/index.php/ecletica	PROPN
ecletica-1322	80	30	https://doi.org/10.26850/1678-4618eqj.v47.4.2022.p27-36	https://doi.org/10.26850/1678-4618eqj.v47.4.2022.p27-36	NOUN
ecletica-1322	80	31	original	original	ADJ
ecletica-1322	80	32	article	article	NOUN
ecletica-1322	80	33	revista.iq.unesp.br	revista.iq.unesp.br	PUNCT
ecletica-1322	80	34	32	32	NUM
ecletica-1322	80	35	eclética	eclética	PROPN
ecletica-1322	80	36	química	química	PROPN
ecletica-1322	80	37	journal	journal	PROPN
ecletica-1322	80	38	,	,	PUNCT
ecletica-1322	80	39	vol	vol	NOUN
ecletica-1322	80	40	.	.	PROPN
ecletica-1322	81	1	47	47	NUM
ecletica-1322	81	2	,	,	PUNCT
ecletica-1322	81	3	n.	n.	NOUN
ecletica-1322	81	4	4	4	NUM
ecletica-1322	81	5	,	,	PUNCT
ecletica-1322	81	6	2022	2022	NUM
ecletica-1322	81	7	,	,	PUNCT
ecletica-1322	81	8	27	27	NUM
ecletica-1322	81	9	-	-	SYM
ecletica-1322	81	10	36	36	NUM
ecletica-1322	81	11	issn	issn	NOUN
ecletica-1322	81	12	:	:	PUNCT
ecletica-1322	81	13	1678	1678	NUM
ecletica-1322	81	14	-	-	SYM
ecletica-1322	81	15	4618	4618	NUM
ecletica-1322	81	16	doi	doi	NOUN
ecletica-1322	81	17	:	:	PUNCT
ecletica-1322	81	18	10.26850/1678	10.26850/1678	NUM
ecletica-1322	81	19	-	-	SYM
ecletica-1322	81	20	4618eqj.v47.4.2022.p27	4618eqj.v47.4.2022.p27	NUM
ecletica-1322	81	21	-	-	PUNCT
ecletica-1322	81	22	36	36	NUM
ecletica-1322	81	23	orally	orally	ADV
ecletica-1322	81	24	.	.	PUNCT
ecletica-1322	82	1	compounds	compound	NOUN
ecletica-1322	82	2	d	d	NOUN
ecletica-1322	82	3	,	,	PUNCT
ecletica-1322	82	4	e	e	PROPN
ecletica-1322	82	5	,	,	PUNCT
ecletica-1322	82	6	f	f	PROPN
ecletica-1322	82	7	have	have	VERB
ecletica-1322	82	8	their	their	PRON
ecletica-1322	82	9	log	log	NOUN
ecletica-1322	82	10	p	p	NOUN
ecletica-1322	82	11	values	value	NOUN
ecletica-1322	82	12	(	(	PUNCT
ecletica-1322	82	13	0.59	0.59	NUM
ecletica-1322	82	14	–	–	PUNCT
ecletica-1322	82	15	0.7	0.7	NUM
ecletica-1322	82	16	)	)	PUNCT
ecletica-1322	82	17	less	less	ADJ
ecletica-1322	82	18	than	than	ADP
ecletica-1322	82	19	1	1	NUM
ecletica-1322	82	20	,	,	PUNCT
ecletica-1322	82	21	being	be	AUX
ecletica-1322	82	22	closer	close	ADJ
ecletica-1322	82	23	to	to	ADP
ecletica-1322	82	24	that	that	PRON
ecletica-1322	82	25	of	of	ADP
ecletica-1322	82	26	the	the	DET
ecletica-1322	82	27	standard	standard	NOUN
ecletica-1322	82	28	—	—	PUNCT
ecletica-1322	82	29	metronidazole	metronidazole	NOUN
ecletica-1322	82	30	(	(	PUNCT
ecletica-1322	82	31	0.42	0.42	NUM
ecletica-1322	82	32	)	)	PUNCT
ecletica-1322	82	33	.	.	PUNCT
ecletica-1322	83	1	furthermore	furthermore	ADV
ecletica-1322	83	2	,	,	PUNCT
ecletica-1322	83	3	for	for	SCONJ
ecletica-1322	83	4	compounds	compound	NOUN
ecletica-1322	83	5	to	to	PART
ecletica-1322	83	6	be	be	AUX
ecletica-1322	83	7	useful	useful	ADJ
ecletica-1322	83	8	in	in	ADP
ecletica-1322	83	9	drug	drug	NOUN
ecletica-1322	83	10	formulation	formulation	NOUN
ecletica-1322	83	11	targeted	target	VERB
ecletica-1322	83	12	at	at	ADP
ecletica-1322	83	13	central	central	ADJ
ecletica-1322	83	14	nervous	nervous	ADJ
ecletica-1322	83	15	system	system	NOUN
ecletica-1322	83	16	,	,	PUNCT
ecletica-1322	83	17	and	and	CCONJ
ecletica-1322	83	18	intestinal	intestinal	ADJ
ecletica-1322	83	19	absorption	absorption	NOUN
ecletica-1322	83	20	,	,	PUNCT
ecletica-1322	83	21	their	their	PRON
ecletica-1322	83	22	log	log	NOUN
ecletica-1322	83	23	p	p	NOUN
ecletica-1322	83	24	should	should	AUX
ecletica-1322	83	25	fall	fall	VERB
ecletica-1322	83	26	in	in	ADP
ecletica-1322	83	27	the	the	DET
ecletica-1322	83	28	range	range	NOUN
ecletica-1322	83	29	;	;	PUNCT
ecletica-1322	83	30	1.35–1.8	1.35–1.8	NUM
ecletica-1322	83	31	(	(	PUNCT
ecletica-1322	83	32	adegoke	adegoke	VERB
ecletica-1322	83	33	et	et	PROPN
ecletica-1322	83	34	al	al	PROPN
ecletica-1322	83	35	.	.	PROPN
ecletica-1322	83	36	,	,	PUNCT
ecletica-1322	83	37	2020	2020	NUM
ecletica-1322	83	38	)	)	PUNCT
ecletica-1322	83	39	.	.	PUNCT
ecletica-1322	84	1	this	this	PRON
ecletica-1322	84	2	was	be	AUX
ecletica-1322	84	3	observed	observe	VERB
ecletica-1322	84	4	for	for	ADP
ecletica-1322	84	5	compounds	compound	NOUN
ecletica-1322	84	6	b	b	PROPN
ecletica-1322	84	7	(	(	PUNCT
ecletica-1322	84	8	1.28	1.28	NUM
ecletica-1322	84	9	)	)	PUNCT
ecletica-1322	84	10	,	,	PUNCT
ecletica-1322	84	11	while	while	SCONJ
ecletica-1322	84	12	the	the	DET
ecletica-1322	84	13	log	log	NOUN
ecletica-1322	84	14	p	p	NOUN
ecletica-1322	84	15	for	for	ADP
ecletica-1322	84	16	compound	compound	NOUN
ecletica-1322	84	17	c	c	NOUN
ecletica-1322	84	18	is	be	AUX
ecletica-1322	84	19	slightly	slightly	ADV
ecletica-1322	84	20	greater	great	ADJ
ecletica-1322	84	21	than	than	ADP
ecletica-1322	84	22	3	3	NUM
ecletica-1322	84	23	(	(	PUNCT
ecletica-1322	84	24	tab	tab	NOUN
ecletica-1322	84	25	.	.	NOUN
ecletica-1322	84	26	2	2	NUM
ecletica-1322	84	27	)	)	PUNCT
ecletica-1322	84	28	.	.	PUNCT
ecletica-1322	85	1	table	table	NOUN
ecletica-1322	85	2	2	2	NUM
ecletica-1322	85	3	.	.	PUNCT
ecletica-1322	85	4	calculated	calculate	VERB
ecletica-1322	85	5	descriptors	descriptor	NOUN
ecletica-1322	85	6	for	for	ADP
ecletica-1322	85	7	the	the	DET
ecletica-1322	85	8	studied	study	VERB
ecletica-1322	85	9	compounds	compound	NOUN
ecletica-1322	85	10	.	.	PUNCT
ecletica-1322	86	1	mol	mol	ADP
ecletica-1322	86	2	a	a	DET
ecletica-1322	86	3	b	b	NOUN
ecletica-1322	86	4	c	c	NOUN
ecletica-1322	86	5	d	d	X
ecletica-1322	86	6	e	e	X
ecletica-1322	86	7	f	f	X
ecletica-1322	86	8	mw	mw	X
ecletica-1322	86	9	(	(	PUNCT
ecletica-1322	86	10	amu	amu	PROPN
ecletica-1322	86	11	)	)	PUNCT
ecletica-1322	86	12	molecular	molecular	ADJ
ecletica-1322	86	13	weight	weight	NOUN
ecletica-1322	87	1	171.15	171.15	NUM
ecletica-1322	87	2	155.15	155.15	NUM
ecletica-1322	87	3	277.34	277.34	NUM
ecletica-1322	87	4	199.16	199.16	NUM
ecletica-1322	87	5	200.15	200.15	NUM
ecletica-1322	87	6	185.18	185.18	NUM
ecletica-1322	87	7	dm	dm	PROPN
ecletica-1322	87	8	(	(	PUNCT
ecletica-1322	87	9	debye	debye	ADJ
ecletica-1322	87	10	)	)	PUNCT
ecletica-1322	87	11	dipole	dipole	NOUN
ecletica-1322	87	12	moment	moment	NOUN
ecletica-1322	87	13	4.55	4.55	NUM
ecletica-1322	88	1	4.89	4.89	NUM
ecletica-1322	88	2	2.98	2.98	NUM
ecletica-1322	88	3	4.29	4.29	NUM
ecletica-1322	88	4	3.88	3.88	NUM
ecletica-1322	88	5	3.59	3.59	NUM
ecletica-1322	88	6	ehomo	ehomo	NOUN
ecletica-1322	88	7	(	(	PUNCT
ecletica-1322	88	8	ev	ev	INTJ
ecletica-1322	88	9	)	)	PUNCT
ecletica-1322	88	10	highest	high	ADJ
ecletica-1322	88	11	occupied	occupy	VERB
ecletica-1322	88	12	molecular	molecular	ADJ
ecletica-1322	88	13	orbital	orbital	NOUN
ecletica-1322	88	14	–	–	PUNCT
ecletica-1322	88	15	6.80	6.80	NUM
ecletica-1322	88	16	–	–	PUNCT
ecletica-1322	88	17	6.90	6.90	NUM
ecletica-1322	88	18	–	–	PUNCT
ecletica-1322	88	19	6.26	6.26	NUM
ecletica-1322	88	20	–	–	PUNCT
ecletica-1322	88	21	7.03	7.03	NUM
ecletica-1322	88	22	–	–	PUNCT
ecletica-1322	88	23	7.35	7.35	NUM
ecletica-1322	88	24	–	–	PUNCT
ecletica-1322	88	25	6.95	6.95	NUM
ecletica-1322	88	26	elumo	elumo	ADJ
ecletica-1322	88	27	(	(	PUNCT
ecletica-1322	88	28	ev	ev	INTJ
ecletica-1322	88	29	)	)	PUNCT
ecletica-1322	88	30	lowest	low	ADJ
ecletica-1322	88	31	unoccupied	unoccupied	ADJ
ecletica-1322	88	32	molecular	molecular	ADJ
ecletica-1322	88	33	orbital	orbital	NOUN
ecletica-1322	88	34	–	–	PUNCT
ecletica-1322	88	35	2.26	2.26	NUM
ecletica-1322	88	36	–	–	PUNCT
ecletica-1322	88	37	2.29	2.29	NUM
ecletica-1322	88	38	–	–	PUNCT
ecletica-1322	88	39	2.32	2.32	NUM
ecletica-1322	88	40	–	–	PUNCT
ecletica-1322	88	41	2.41	2.41	NUM
ecletica-1322	88	42	–	–	PUNCT
ecletica-1322	88	43	2.72	2.72	NUM
ecletica-1322	88	44	–	–	PUNCT
ecletica-1322	88	45	2.39	2.39	NUM
ecletica-1322	88	46	band	band	NOUN
ecletica-1322	88	47	gap	gap	NOUN
ecletica-1322	88	48	band	band	NOUN
ecletica-1322	88	49	gap	gap	NOUN
ecletica-1322	88	50	4.54	4.54	NUM
ecletica-1322	88	51	4.61	4.61	NUM
ecletica-1322	88	52	3.94	3.94	NUM
ecletica-1322	88	53	4.62	4.62	NUM
ecletica-1322	88	54	4.63	4.63	NUM
ecletica-1322	88	55	4.56	4.56	NUM
ecletica-1322	88	56	hba	hba	NOUN
ecletica-1322	88	57	hydrogen	hydrogen	NOUN
ecletica-1322	88	58	bond	bond	NOUN
ecletica-1322	88	59	accept	accept	VERB
ecletica-1322	88	60	5	5	NUM
ecletica-1322	88	61	4	4	NUM
ecletica-1322	88	62	5	5	NUM
ecletica-1322	88	63	5	5	NUM
ecletica-1322	88	64	5	5	NUM
ecletica-1322	88	65	5	5	NUM
ecletica-1322	88	66	hbd	hbd	NOUN
ecletica-1322	88	67	hydrogen	hydrogen	NOUN
ecletica-1322	88	68	bond	bond	NOUN
ecletica-1322	88	69	donor	donor	NOUN
ecletica-1322	88	70	1	1	NUM
ecletica-1322	88	71	0	0	NUM
ecletica-1322	88	72	0	0	NUM
ecletica-1322	88	73	1	1	NUM
ecletica-1322	88	74	0	0	NUM
ecletica-1322	88	75	0	0	NUM
ecletica-1322	88	76	log	log	NOUN
ecletica-1322	88	77	p	p	NOUN
ecletica-1322	88	78	lipophilicity	lipophilicity	NOUN
ecletica-1322	88	79	0.42	0.42	NUM
ecletica-1322	88	80	1.28	1.28	NUM
ecletica-1322	88	81	3.45	3.45	NUM
ecletica-1322	88	82	0.70	0.70	NUM
ecletica-1322	88	83	0.59	0.59	NUM
ecletica-1322	88	84	0.78	0.78	NUM
ecletica-1322	88	85	ovality	ovality	NOUN
ecletica-1322	88	86	ovality	ovality	NOUN
ecletica-1322	88	87	1.30	1.30	NUM
ecletica-1322	88	88	1.29	1.29	NUM
ecletica-1322	88	89	1.47	1.47	NUM
ecletica-1322	88	90	1.35	1.35	NUM
ecletica-1322	88	91	1.35	1.35	NUM
ecletica-1322	88	92	1.36	1.36	NUM
ecletica-1322	88	93	psa	psa	NOUN
ecletica-1322	88	94	(	(	PUNCT
ecletica-1322	88	95	a2	a2	PROPN
ecletica-1322	88	96	)	)	PUNCT
ecletica-1322	88	97	polar	polar	ADJ
ecletica-1322	88	98	surface	surface	NOUN
ecletica-1322	88	99	area	area	NOUN
ecletica-1322	88	100	65.15	65.15	NUM
ecletica-1322	88	101	46.30	46.30	NUM
ecletica-1322	88	102	46.06	46.06	NUM
ecletica-1322	88	103	80.15	80.15	NUM
ecletica-1322	88	104	85.44	85.44	NUM
ecletica-1322	88	105	53.77	53.77	NUM
ecletica-1322	88	106	se	se	X
ecletica-1322	88	107	(	(	PUNCT
ecletica-1322	88	108	kj	kj	PROPN
ecletica-1322	88	109	/	/	SYM
ecletica-1322	88	110	mol	mol	PROPN
ecletica-1322	88	111	)	)	PUNCT
ecletica-1322	88	112	solvation	solvation	NOUN
ecletica-1322	88	113	energy	energy	NOUN
ecletica-1322	88	114	–	–	PUNCT
ecletica-1322	88	115	37.24	37.24	NUM
ecletica-1322	88	116	–	–	PUNCT
ecletica-1322	88	117	27.70	27.70	NUM
ecletica-1322	88	118	–	–	SYM
ecletica-1322	88	119	45.09	45.09	NUM
ecletica-1322	88	120	–	–	PUNCT
ecletica-1322	88	121	43.64	43.64	NUM
ecletica-1322	88	122	–	–	SYM
ecletica-1322	88	123	34.32	34.32	NUM
ecletica-1322	88	124	–	–	PUNCT
ecletica-1322	88	125	31.80	31.80	NUM
ecletica-1322	88	126	note	note	NOUN
ecletica-1322	88	127	:	:	PUNCT
ecletica-1322	88	128	referenced	reference	VERB
ecletica-1322	88	129	drug	drug	NOUN
ecletica-1322	88	130	=	=	SYM
ecletica-1322	88	131	compound	compound	VERB
ecletica-1322	88	132	a	a	DET
ecletica-1322	88	133	=	=	NOUN
ecletica-1322	88	134	metronidazole	metronidazole	NOUN
ecletica-1322	88	135	.	.	PUNCT
ecletica-1322	89	1	solvation	solvation	NOUN
ecletica-1322	89	2	energy	energy	NOUN
ecletica-1322	89	3	,	,	PUNCT
ecletica-1322	89	4	a	a	DET
ecletica-1322	89	5	measure	measure	NOUN
ecletica-1322	89	6	of	of	ADP
ecletica-1322	89	7	interaction	interaction	NOUN
ecletica-1322	89	8	of	of	ADP
ecletica-1322	89	9	solute	solute	NOUN
ecletica-1322	89	10	with	with	ADP
ecletica-1322	89	11	solvent	solvent	NOUN
ecletica-1322	89	12	that	that	PRON
ecletica-1322	89	13	leads	lead	VERB
ecletica-1322	89	14	to	to	ADP
ecletica-1322	89	15	stabilization	stabilization	NOUN
ecletica-1322	89	16	of	of	ADP
ecletica-1322	89	17	species	specie	NOUN
ecletica-1322	89	18	in	in	ADP
ecletica-1322	89	19	solution	solution	NOUN
ecletica-1322	89	20	,	,	PUNCT
ecletica-1322	89	21	is	be	AUX
ecletica-1322	89	22	also	also	ADV
ecletica-1322	89	23	highly	highly	ADV
ecletica-1322	89	24	significant	significant	ADJ
ecletica-1322	89	25	in	in	ADP
ecletica-1322	89	26	drugs	drug	NOUN
ecletica-1322	89	27	development	development	NOUN
ecletica-1322	89	28	.	.	PUNCT
ecletica-1322	90	1	the	the	DET
ecletica-1322	90	2	highest	high	ADJ
ecletica-1322	90	3	solvation	solvation	NOUN
ecletica-1322	90	4	energies	energy	NOUN
ecletica-1322	90	5	recorded	record	VERB
ecletica-1322	90	6	for	for	ADP
ecletica-1322	90	7	compound	compound	NOUN
ecletica-1322	90	8	c	c	PROPN
ecletica-1322	90	9	is	be	AUX
ecletica-1322	90	10	an	an	DET
ecletica-1322	90	11	indication	indication	NOUN
ecletica-1322	90	12	that	that	SCONJ
ecletica-1322	90	13	its	its	PRON
ecletica-1322	90	14	interaction	interaction	NOUN
ecletica-1322	90	15	with	with	ADP
ecletica-1322	90	16	solvent	solvent	NOUN
ecletica-1322	90	17	will	will	AUX
ecletica-1322	90	18	be	be	AUX
ecletica-1322	90	19	more	more	ADV
ecletica-1322	90	20	thermodynamically	thermodynamically	ADV
ecletica-1322	90	21	favored	favor	VERB
ecletica-1322	90	22	than	than	ADP
ecletica-1322	90	23	other	other	ADJ
ecletica-1322	90	24	studied	study	VERB
ecletica-1322	90	25	molecules	molecule	NOUN
ecletica-1322	90	26	(	(	PUNCT
ecletica-1322	90	27	choi	choi	NOUN
ecletica-1322	90	28	et	et	PROPN
ecletica-1322	90	29	al	al	PROPN
ecletica-1322	90	30	.	.	PROPN
ecletica-1322	90	31	,	,	PUNCT
ecletica-1322	90	32	2013	2013	NUM
ecletica-1322	90	33	)	)	PUNCT
ecletica-1322	90	34	.	.	PUNCT
ecletica-1322	91	1	the	the	DET
ecletica-1322	91	2	trends	trend	NOUN
ecletica-1322	91	3	in	in	ADP
ecletica-1322	91	4	the	the	DET
ecletica-1322	91	5	polar	polar	ADJ
ecletica-1322	91	6	surface	surface	NOUN
ecletica-1322	91	7	area	area	NOUN
ecletica-1322	91	8	of	of	ADP
ecletica-1322	91	9	the	the	DET
ecletica-1322	91	10	compounds	compound	NOUN
ecletica-1322	91	11	(	(	PUNCT
ecletica-1322	91	12	c	c	X
ecletica-1322	91	13	<	<	X
ecletica-1322	91	14	b	b	X
ecletica-1322	91	15	<	<	X
ecletica-1322	91	16	f	f	X
ecletica-1322	91	17	<	<	X
ecletica-1322	91	18	a	a	PRON
ecletica-1322	91	19	<	<	X
ecletica-1322	91	20	d	d	X
ecletica-1322	91	21	<	<	X
ecletica-1322	91	22	e	e	NOUN
ecletica-1322	91	23	)	)	PUNCT
ecletica-1322	91	24	differ	differ	VERB
ecletica-1322	91	25	from	from	ADP
ecletica-1322	91	26	their	their	PRON
ecletica-1322	91	27	volumes	volume	NOUN
ecletica-1322	91	28	(	(	PUNCT
ecletica-1322	91	29	b	b	X
ecletica-1322	91	30	<	<	X
ecletica-1322	91	31	a	a	X
ecletica-1322	91	32	<	<	X
ecletica-1322	91	33	e	e	X
ecletica-1322	91	34	<	<	X
ecletica-1322	91	35	f	f	X
ecletica-1322	91	36	<	<	X
ecletica-1322	91	37	d	d	X
ecletica-1322	91	38	<	<	X
ecletica-1322	91	39	c	c	NOUN
ecletica-1322	91	40	)	)	PUNCT
ecletica-1322	91	41	,	,	PUNCT
ecletica-1322	91	42	and	and	CCONJ
ecletica-1322	91	43	molecular	molecular	ADJ
ecletica-1322	91	44	weight	weight	NOUN
ecletica-1322	91	45	(	(	PUNCT
ecletica-1322	91	46	b	b	NOUN
ecletica-1322	91	47	<	<	X
ecletica-1322	91	48	a	a	X
ecletica-1322	91	49	<	<	X
ecletica-1322	91	50	f	f	X
ecletica-1322	91	51	<	<	X
ecletica-1322	91	52	d	d	X
ecletica-1322	91	53	<	<	X
ecletica-1322	91	54	e	e	X
ecletica-1322	91	55	<	<	X
ecletica-1322	91	56	c	c	PROPN
ecletica-1322	91	57	)	)	PUNCT
ecletica-1322	91	58	variations	variation	NOUN
ecletica-1322	91	59	.	.	PUNCT
ecletica-1322	92	1	ovality	ovality	NOUN
ecletica-1322	92	2	is	be	AUX
ecletica-1322	92	3	related	relate	VERB
ecletica-1322	92	4	to	to	ADP
ecletica-1322	92	5	molecular	molecular	ADJ
ecletica-1322	92	6	surface	surface	NOUN
ecletica-1322	92	7	area	area	NOUN
ecletica-1322	92	8	and	and	CCONJ
ecletica-1322	92	9	van	van	PROPN
ecletica-1322	92	10	der	der	PROPN
ecletica-1322	92	11	waal	waal	PROPN
ecletica-1322	92	12	’s	’s	PART
ecletica-1322	92	13	volume	volume	NOUN
ecletica-1322	92	14	;	;	PUNCT
ecletica-1322	92	15	it	it	PRON
ecletica-1322	92	16	increases	increase	VERB
ecletica-1322	92	17	with	with	ADP
ecletica-1322	92	18	increasing	increase	VERB
ecletica-1322	92	19	structural	structural	ADJ
ecletica-1322	92	20	linearity	linearity	NOUN
ecletica-1322	92	21	and	and	CCONJ
ecletica-1322	92	22	deviate	deviate	VERB
ecletica-1322	92	23	from	from	ADP
ecletica-1322	92	24	spherical	spherical	ADJ
ecletica-1322	92	25	form	form	NOUN
ecletica-1322	92	26	,	,	PUNCT
ecletica-1322	92	27	which	which	PRON
ecletica-1322	92	28	is	be	AUX
ecletica-1322	92	29	usually	usually	ADV
ecletica-1322	92	30	1	1	NUM
ecletica-1322	92	31	for	for	ADP
ecletica-1322	92	32	spherical	spherical	ADJ
ecletica-1322	92	33	shape	shape	NOUN
ecletica-1322	92	34	molecules	molecule	NOUN
ecletica-1322	92	35	(	(	PUNCT
ecletica-1322	92	36	abdul	abdul	PROPN
ecletica-1322	92	37	-	-	PUNCT
ecletica-1322	92	38	hammed	hammed	PROPN
ecletica-1322	92	39	et	et	PROPN
ecletica-1322	92	40	al	al	PROPN
ecletica-1322	92	41	.	.	PROPN
ecletica-1322	92	42	,	,	PUNCT
ecletica-1322	92	43	2020	2020	NUM
ecletica-1322	92	44	)	)	PUNCT
ecletica-1322	92	45	.	.	PUNCT
ecletica-1322	93	1	the	the	DET
ecletica-1322	93	2	reported	report	VERB
ecletica-1322	93	3	trend	trend	NOUN
ecletica-1322	93	4	in	in	ADP
ecletica-1322	93	5	the	the	DET
ecletica-1322	93	6	ovality	ovality	NOUN
ecletica-1322	93	7	values	value	NOUN
ecletica-1322	93	8	of	of	ADP
ecletica-1322	93	9	the	the	DET
ecletica-1322	93	10	studied	study	VERB
ecletica-1322	93	11	compounds	compound	NOUN
ecletica-1322	93	12	:	:	PUNCT
ecletica-1322	93	13	b	b	X
ecletica-1322	93	14	(	(	PUNCT
ecletica-1322	93	15	1.29	1.29	NUM
ecletica-1322	93	16	)	)	PUNCT
ecletica-1322	93	17	<	<	X
ecletica-1322	93	18	a	a	DET
ecletica-1322	93	19	(	(	PUNCT
ecletica-1322	93	20	1.30	1.30	NUM
ecletica-1322	93	21	)	)	PUNCT
ecletica-1322	93	22	<	<	X
ecletica-1322	94	1	d	d	X
ecletica-1322	94	2	(	(	PUNCT
ecletica-1322	94	3	1.35	1.35	NUM
ecletica-1322	94	4	)	)	PUNCT
ecletica-1322	94	5	=	=	NOUN
ecletica-1322	94	6	e	e	X
ecletica-1322	94	7	(	(	PUNCT
ecletica-1322	94	8	1.35	1.35	NUM
ecletica-1322	94	9	)	)	PUNCT
ecletica-1322	94	10	<	<	X
ecletica-1322	94	11	f	f	X
ecletica-1322	94	12	(	(	PUNCT
ecletica-1322	94	13	1.36	1.36	NUM
ecletica-1322	94	14	)	)	PUNCT
ecletica-1322	94	15	<	<	X
ecletica-1322	94	16	c	c	X
ecletica-1322	94	17	(	(	PUNCT
ecletica-1322	94	18	1.49	1.49	NUM
ecletica-1322	94	19	)	)	PUNCT
ecletica-1322	94	20	,	,	PUNCT
ecletica-1322	94	21	suggests	suggest	VERB
ecletica-1322	94	22	that	that	SCONJ
ecletica-1322	94	23	compound	compound	NOUN
ecletica-1322	94	24	c	c	PROPN
ecletica-1322	94	25	vary	vary	VERB
ecletica-1322	94	26	more	more	ADV
ecletica-1322	94	27	greatly	greatly	ADV
ecletica-1322	94	28	from	from	ADP
ecletica-1322	94	29	spherical	spherical	ADJ
ecletica-1322	94	30	shape	shape	NOUN
ecletica-1322	94	31	than	than	ADP
ecletica-1322	94	32	the	the	DET
ecletica-1322	94	33	other	other	ADJ
ecletica-1322	94	34	compounds	compound	NOUN
ecletica-1322	94	35	.	.	PUNCT
ecletica-1322	95	1	the	the	DET
ecletica-1322	95	2	dipole	dipole	NOUN
ecletica-1322	95	3	moment	moment	NOUN
ecletica-1322	95	4	and	and	CCONJ
ecletica-1322	95	5	polarizability	polarizability	NOUN
ecletica-1322	95	6	of	of	ADP
ecletica-1322	95	7	molecule	molecule	NOUN
ecletica-1322	95	8	which	which	PRON
ecletica-1322	95	9	measure	measure	VERB
ecletica-1322	95	10	the	the	DET
ecletica-1322	95	11	bond	bond	NOUN
ecletica-1322	95	12	properties	property	NOUN
ecletica-1322	95	13	(	(	PUNCT
ecletica-1322	95	14	induction	induction	NOUN
ecletica-1322	95	15	polarization	polarization	NOUN
ecletica-1322	95	16	)	)	PUNCT
ecletica-1322	95	17	,	,	PUNCT
ecletica-1322	95	18	charge	charge	VERB
ecletica-1322	95	19	densities	density	NOUN
ecletica-1322	95	20	and	and	CCONJ
ecletica-1322	95	21	nonbonding	nonbonde	VERB
ecletica-1322	95	22	interactions	interaction	NOUN
ecletica-1322	95	23	between	between	ADP
ecletica-1322	95	24	ligand	ligand	NOUN
ecletica-1322	95	25	and	and	CCONJ
ecletica-1322	95	26	receptor	receptor	NOUN
ecletica-1322	95	27	of	of	ADP
ecletica-1322	95	28	molecules	molecule	NOUN
ecletica-1322	95	29	follow	follow	VERB
ecletica-1322	95	30	the	the	DET
ecletica-1322	95	31	trend	trend	NOUN
ecletica-1322	95	32	:	:	PUNCT
ecletica-1322	95	33	b	b	X
ecletica-1322	95	34	>	>	X
ecletica-1322	95	35	a	a	X
ecletica-1322	95	36	>	>	X
ecletica-1322	95	37	d	d	X
ecletica-1322	95	38	>	>	X
ecletica-1322	95	39	e	e	X
ecletica-1322	95	40	>	>	X
ecletica-1322	95	41	f	f	PROPN
ecletica-1322	95	42	>	>	X
ecletica-1322	95	43	c.	c.	PROPN
ecletica-1322	95	44	as	as	SCONJ
ecletica-1322	95	45	reported	report	VERB
ecletica-1322	95	46	by	by	ADP
ecletica-1322	95	47	adeoye	adeoye	PROPN
ecletica-1322	95	48	et	et	PROPN
ecletica-1322	95	49	al	al	PROPN
ecletica-1322	95	50	.	.	PROPN
ecletica-1322	96	1	(	(	PUNCT
ecletica-1322	96	2	2017	2017	NUM
ecletica-1322	96	3	)	)	PUNCT
ecletica-1322	96	4	and	and	CCONJ
ecletica-1322	96	5	oyewole	oyewole	NOUN
ecletica-1322	96	6	et	et	PROPN
ecletica-1322	96	7	al	al	PROPN
ecletica-1322	96	8	.	.	PROPN
ecletica-1322	97	1	(	(	PUNCT
ecletica-1322	97	2	2020	2020	NUM
ecletica-1322	97	3	)	)	PUNCT
ecletica-1322	97	4	,	,	PUNCT
ecletica-1322	97	5	the	the	DET
ecletica-1322	97	6	unpredictable	unpredictable	ADJ
ecletica-1322	97	7	properties	property	NOUN
ecletica-1322	97	8	of	of	ADP
ecletica-1322	97	9	drug	drug	NOUN
ecletica-1322	97	10	-	-	PUNCT
ecletica-1322	97	11	like	like	ADJ
ecletica-1322	97	12	molecules	molecule	NOUN
ecletica-1322	97	13	may	may	AUX
ecletica-1322	97	14	arise	arise	VERB
ecletica-1322	97	15	as	as	ADP
ecletica-1322	97	16	a	a	DET
ecletica-1322	97	17	result	result	NOUN
ecletica-1322	97	18	of	of	ADP
ecletica-1322	97	19	large	large	ADJ
ecletica-1322	97	20	dipole	dipole	NOUN
ecletica-1322	97	21	moment	moment	NOUN
ecletica-1322	97	22	value	value	NOUN
ecletica-1322	97	23	,	,	PUNCT
ecletica-1322	97	24	molecules	molecule	NOUN
ecletica-1322	97	25	with	with	ADP
ecletica-1322	97	26	better	well	ADJ
ecletica-1322	97	27	charge	charge	NOUN
ecletica-1322	97	28	distribution	distribution	NOUN
ecletica-1322	97	29	and	and	CCONJ
ecletica-1322	97	30	increasing	increase	VERB
ecletica-1322	97	31	distance	distance	NOUN
ecletica-1322	97	32	will	will	AUX
ecletica-1322	97	33	have	have	VERB
ecletica-1322	97	34	higher	high	ADJ
ecletica-1322	97	35	dipole	dipole	NOUN
ecletica-1322	97	36	moment	moment	NOUN
ecletica-1322	97	37	and	and	CCONJ
ecletica-1322	97	38	polarizability	polarizability	NOUN
ecletica-1322	97	39	.	.	PUNCT
ecletica-1322	98	1	thus	thus	ADV
ecletica-1322	98	2	,	,	PUNCT
ecletica-1322	98	3	the	the	DET
ecletica-1322	98	4	studied	study	VERB
ecletica-1322	98	5	compounds	compound	NOUN
ecletica-1322	98	6	may	may	AUX
ecletica-1322	98	7	possibly	possibly	ADV
ecletica-1322	98	8	have	have	VERB
ecletica-1322	98	9	strong	strong	ADJ
ecletica-1322	98	10	nonbonded	nonbonded	ADJ
ecletica-1322	98	11	connections	connection	NOUN
ecletica-1322	98	12	with	with	ADP
ecletica-1322	98	13	the	the	DET
ecletica-1322	98	14	target	target	NOUN
ecletica-1322	98	15	nitroreductase	nitroreductase	NOUN
ecletica-1322	98	16	rdxa	rdxa	NOUN
ecletica-1322	98	17	proteins	protein	NOUN
ecletica-1322	98	18	(	(	PUNCT
ecletica-1322	98	19	pdb	pdb	NOUN
ecletica-1322	98	20	i	i	PROPN
ecletica-1322	98	21	d	d	PROPN
ecletica-1322	98	22	:	:	PUNCT
ecletica-1322	98	23	3qdl	3qdl	NUM
ecletica-1322	98	24	)	)	PUNCT
ecletica-1322	98	25	.	.	PUNCT
ecletica-1322	99	1	3.2	3.2	NUM
ecletica-1322	99	2	molecular	molecular	ADJ
ecletica-1322	99	3	docking	docking	NOUN
ecletica-1322	99	4	and	and	CCONJ
ecletica-1322	99	5	adme	adme	VERB
ecletica-1322	99	6	studies	study	NOUN
ecletica-1322	99	7	a	a	DET
ecletica-1322	99	8	docking	docking	NOUN
ecletica-1322	99	9	study	study	NOUN
ecletica-1322	99	10	was	be	AUX
ecletica-1322	99	11	used	use	VERB
ecletica-1322	99	12	to	to	PART
ecletica-1322	99	13	predict	predict	VERB
ecletica-1322	99	14	the	the	DET
ecletica-1322	99	15	preferred	preferred	ADJ
ecletica-1322	99	16	orientation	orientation	NOUN
ecletica-1322	99	17	or	or	CCONJ
ecletica-1322	99	18	correct	correct	ADJ
ecletica-1322	99	19	conformation	conformation	NOUN
ecletica-1322	99	20	of	of	ADP
ecletica-1322	99	21	the	the	DET
ecletica-1322	99	22	ligand	ligand	NOUN
ecletica-1322	99	23	in	in	ADP
ecletica-1322	99	24	the	the	DET
ecletica-1322	99	25	active	active	ADJ
ecletica-1322	99	26	site	site	NOUN
ecletica-1322	99	27	of	of	ADP
ecletica-1322	99	28	the	the	DET
ecletica-1322	99	29	protein	protein	NOUN
ecletica-1322	99	30	.	.	PUNCT
ecletica-1322	100	1	the	the	DET
ecletica-1322	100	2	binding	bind	VERB
ecletica-1322	100	3	energy	energy	NOUN
ecletica-1322	100	4	measure	measure	NOUN
ecletica-1322	100	5	of	of	ADP
ecletica-1322	100	6	binding	bind	VERB
ecletica-1322	100	7	affinity	affinity	NOUN
ecletica-1322	100	8	is	be	AUX
ecletica-1322	100	9	an	an	DET
ecletica-1322	100	10	important	important	ADJ
ecletica-1322	100	11	parameter	parameter	NOUN
ecletica-1322	100	12	generated	generate	VERB
ecletica-1322	100	13	from	from	ADP
ecletica-1322	100	14	molecular	molecular	ADJ
ecletica-1322	100	15	docking	docking	NOUN
ecletica-1322	100	16	to	to	PART
ecletica-1322	100	17	provide	provide	VERB
ecletica-1322	100	18	information	information	NOUN
ecletica-1322	100	19	on	on	ADP
ecletica-1322	100	20	the	the	DET
ecletica-1322	100	21	strength	strength	NOUN
ecletica-1322	100	22	of	of	ADP
ecletica-1322	100	23	the	the	DET
ecletica-1322	100	24	interaction	interaction	NOUN
ecletica-1322	100	25	between	between	ADP
ecletica-1322	100	26	the	the	DET
ecletica-1322	100	27	ligand	ligand	NOUN
ecletica-1322	100	28	and	and	CCONJ
ecletica-1322	100	29	receptor	receptor	NOUN
ecletica-1322	100	30	.	.	PUNCT
ecletica-1322	101	1	the	the	DET
ecletica-1322	101	2	interaction	interaction	NOUN
ecletica-1322	101	3	is	be	AUX
ecletica-1322	101	4	spontaneous	spontaneous	ADJ
ecletica-1322	101	5	;	;	PUNCT
ecletica-1322	101	6	the	the	PRON
ecletica-1322	101	7	greater	great	ADJ
ecletica-1322	101	8	the	the	DET
ecletica-1322	101	9	binding	bind	VERB
ecletica-1322	101	10	affinity	affinity	NOUN
ecletica-1322	101	11	(	(	PUNCT
ecletica-1322	101	12	in	in	ADP
ecletica-1322	101	13	term	term	NOUN
ecletica-1322	101	14	of	of	ADP
ecletica-1322	101	15	negativity	negativity	NOUN
ecletica-1322	101	16	)	)	PUNCT
ecletica-1322	101	17	,	,	PUNCT
ecletica-1322	101	18	the	the	PRON
ecletica-1322	101	19	better	well	ADJ
ecletica-1322	101	20	the	the	DET
ecletica-1322	101	21	inhibition	inhibition	NOUN
ecletica-1322	101	22	(	(	PUNCT
ecletica-1322	101	23	adeoye	adeoye	VERB
ecletica-1322	101	24	et	et	PROPN
ecletica-1322	101	25	al	al	PROPN
ecletica-1322	101	26	.	.	PROPN
ecletica-1322	101	27	,	,	PUNCT
ecletica-1322	101	28	2022	2022	NUM
ecletica-1322	101	29	;	;	PUNCT
ecletica-1322	101	30	ibrahim	ibrahim	PROPN
ecletica-1322	101	31	et	et	PROPN
ecletica-1322	101	32	al	al	PROPN
ecletica-1322	101	33	.	.	PROPN
ecletica-1322	101	34	,	,	PUNCT
ecletica-1322	101	35	2019	2019	NUM
ecletica-1322	101	36	)	)	PUNCT
ecletica-1322	101	37	.	.	PUNCT
ecletica-1322	102	1	consequently	consequently	ADV
ecletica-1322	102	2	,	,	PUNCT
ecletica-1322	102	3	the	the	DET
ecletica-1322	102	4	five	five	NUM
ecletica-1322	102	5	studied	studied	ADJ
ecletica-1322	102	6	compounds	compound	NOUN
ecletica-1322	102	7	(	(	PUNCT
ecletica-1322	102	8	b	b	NOUN
ecletica-1322	102	9	–	–	PUNCT
ecletica-1322	102	10	f	f	X
ecletica-1322	102	11	)	)	PUNCT
ecletica-1322	102	12	were	be	AUX
ecletica-1322	102	13	docked	dock	VERB
ecletica-1322	102	14	against	against	ADP
ecletica-1322	102	15	the	the	DET
ecletica-1322	102	16	target	target	NOUN
ecletica-1322	102	17	(	(	PUNCT
ecletica-1322	102	18	pdb	pdb	PROPN
ecletica-1322	102	19	i	i	PROPN
ecletica-1322	102	20	d	d	PROPN
ecletica-1322	102	21	:	:	PUNCT
ecletica-1322	102	22	3qdl	3qdl	NUM
ecletica-1322	102	23	)	)	PUNCT
ecletica-1322	102	24	to	to	PART
ecletica-1322	102	25	determine	determine	VERB
ecletica-1322	102	26	the	the	DET
ecletica-1322	102	27	nonbonding	nonbonding	NOUN
ecletica-1322	102	28	interactions	interaction	NOUN
ecletica-1322	102	29	present	present	ADJ
ecletica-1322	102	30	in	in	ADP
ecletica-1322	102	31	the	the	DET
ecletica-1322	102	32	studied	studied	ADJ
ecletica-1322	102	33	complex	complex	NOUN
ecletica-1322	102	34	using	use	VERB
ecletica-1322	102	35	metronidazole	metronidazole	NOUN
ecletica-1322	102	36	(	(	PUNCT
ecletica-1322	102	37	a	a	NOUN
ecletica-1322	102	38	)	)	PUNCT
ecletica-1322	102	39	as	as	ADP
ecletica-1322	102	40	the	the	DET
ecletica-1322	102	41	standard	standard	NOUN
ecletica-1322	102	42	.	.	PUNCT
ecletica-1322	103	1	the	the	DET
ecletica-1322	103	2	calculated	calculated	ADJ
ecletica-1322	103	3	binding	bind	VERB
ecletica-1322	103	4	affinities	affinity	NOUN
ecletica-1322	103	5	for	for	ADP
ecletica-1322	103	6	the	the	DET
ecletica-1322	103	7	compounds	compound	NOUN
ecletica-1322	103	8	a	a	DET
ecletica-1322	103	9	–	–	PUNCT
ecletica-1322	103	10	f	f	PROPN
ecletica-1322	103	11	were	be	AUX
ecletica-1322	103	12	–	–	PUNCT
ecletica-1322	103	13	18.8	18.8	NUM
ecletica-1322	103	14	,	,	PUNCT
ecletica-1322	103	15	–	–	PUNCT
ecletica-1322	103	16	18.0	18.0	NUM
ecletica-1322	103	17	,	,	PUNCT
ecletica-1322	103	18	–	–	PUNCT
ecletica-1322	103	19	17.2	17.2	NUM
ecletica-1322	103	20	,	,	PUNCT
ecletica-1322	103	21	–	–	PUNCT
ecletica-1322	103	22	21.3	21.3	NUM
ecletica-1322	103	23	,	,	PUNCT
ecletica-1322	103	24	–	–	PUNCT
ecletica-1322	103	25	21.3	21.3	NUM
ecletica-1322	103	26	and	and	CCONJ
ecletica-1322	103	27	–	–	PUNCT
ecletica-1322	103	28	18.4	18.4	NUM
ecletica-1322	103	29	kj	kj	PROPN
ecletica-1322	103	30	mol–1	mol–1	PROPN
ecletica-1322	103	31	,	,	PUNCT
ecletica-1322	103	32	respectively	respectively	ADV
ecletica-1322	103	33	.	.	PUNCT
ecletica-1322	104	1	compounds	compound	NOUN
ecletica-1322	104	2	d	d	NOUN
ecletica-1322	104	3	and	and	CCONJ
ecletica-1322	104	4	e	e	PROPN
ecletica-1322	104	5	have	have	VERB
ecletica-1322	104	6	the	the	DET
ecletica-1322	104	7	same	same	ADJ
ecletica-1322	104	8	binding	bind	VERB
ecletica-1322	104	9	affinity	affinity	NOUN
ecletica-1322	104	10	(	(	PUNCT
ecletica-1322	104	11	–	–	PUNCT
ecletica-1322	104	12	21.3	21.3	NUM
ecletica-1322	104	13	kj	kj	NOUN
ecletica-1322	104	14	mol–1	mol–1	PROPN
ecletica-1322	104	15	)	)	PUNCT
ecletica-1322	104	16	and	and	CCONJ
ecletica-1322	104	17	inhibition	inhibition	VERB
ecletica-1322	104	18	constant	constant	ADJ
ecletica-1322	104	19	(	(	PUNCT
ecletica-1322	104	20	7.8	7.8	NUM
ecletica-1322	104	21	)	)	PUNCT
ecletica-1322	104	22	which	which	PRON
ecletica-1322	104	23	were	be	AUX
ecletica-1322	104	24	compared	compare	VERB
ecletica-1322	104	25	with	with	ADP
ecletica-1322	104	26	the	the	DET
ecletica-1322	104	27	referenced	reference	VERB
ecletica-1322	104	28	drug	drug	NOUN
ecletica-1322	104	29	(	(	PUNCT
ecletica-1322	104	30	compound	compound	VERB
ecletica-1322	104	31	a	a	DET
ecletica-1322	104	32	[	[	X
ecletica-1322	104	33	metronidazole	metronidazole	NOUN
ecletica-1322	104	34	]	]	PUNCT
ecletica-1322	104	35	)	)	PUNCT
ecletica-1322	104	36	(	(	PUNCT
ecletica-1322	104	37	tab	tab	NOUN
ecletica-1322	104	38	.	.	NOUN
ecletica-1322	104	39	3	3	NUM
ecletica-1322	104	40	and	and	CCONJ
ecletica-1322	104	41	fig	fig	NOUN
ecletica-1322	104	42	.	.	PUNCT
ecletica-1322	105	1	4	4	NUM
ecletica-1322	105	2	)	)	PUNCT
ecletica-1322	105	3	.	.	PUNCT
ecletica-1322	106	1	it	it	PRON
ecletica-1322	106	2	was	be	AUX
ecletica-1322	106	3	observed	observe	VERB
ecletica-1322	106	4	that	that	SCONJ
ecletica-1322	106	5	the	the	DET
ecletica-1322	106	6	addition	addition	NOUN
ecletica-1322	106	7	of	of	ADP
ecletica-1322	106	8	–	–	PUNCT
ecletica-1322	106	9	cooh	cooh	NOUN
ecletica-1322	106	10	and	and	CCONJ
ecletica-1322	106	11	–	–	PUNCT
ecletica-1322	106	12	no2	no2	NOUN
ecletica-1322	106	13	to	to	ADP
ecletica-1322	106	14	the	the	DET
ecletica-1322	106	15	parent	parent	NOUN
ecletica-1322	106	16	compound	compound	NOUN
ecletica-1322	106	17	enhanced	enhance	VERB
ecletica-1322	106	18	it	it	PRON
ecletica-1322	106	19	inhibit	inhibit	VERB
ecletica-1322	106	20	activity	activity	NOUN
ecletica-1322	106	21	.	.	PUNCT
ecletica-1322	107	1	also	also	ADV
ecletica-1322	107	2	,	,	PUNCT
ecletica-1322	107	3	as	as	SCONJ
ecletica-1322	107	4	shown	show	VERB
ecletica-1322	107	5	in	in	ADP
ecletica-1322	107	6	tab	tab	NOUN
ecletica-1322	107	7	.	.	PUNCT
ecletica-1322	108	1	2	2	NUM
ecletica-1322	108	2	,	,	PUNCT
ecletica-1322	108	3	lower	low	ADJ
ecletica-1322	108	4	ability	ability	NOUN
ecletica-1322	108	5	of	of	ADP
ecletica-1322	108	6	compounds	compound	NOUN
ecletica-1322	108	7	d	d	NOUN
ecletica-1322	108	8	and	and	CCONJ
ecletica-1322	108	9	e	e	NOUN
ecletica-1322	108	10	to	to	PART
ecletica-1322	108	11	donate	donate	VERB
ecletica-1322	108	12	electron	electron	NOUN
ecletica-1322	108	13	to	to	PART
ecletica-1322	108	14	target	target	VERB
ecletica-1322	108	15	compounds	compound	NOUN
ecletica-1322	108	16	as	as	ADV
ecletica-1322	108	17	well	well	ADV
ecletica-1322	108	18	as	as	ADP
ecletica-1322	108	19	their	their	PRON
ecletica-1322	108	20	greater	great	ADJ
ecletica-1322	108	21	capacity	capacity	NOUN
ecletica-1322	108	22	to	to	PART
ecletica-1322	108	23	receive	receive	VERB
ecletica-1322	108	24	from	from	ADP
ecletica-1322	108	25	the	the	DET
ecletica-1322	108	26	nearby	nearby	ADJ
ecletica-1322	108	27	compounds	compound	NOUN
ecletica-1322	108	28	enhanced	enhance	VERB
ecletica-1322	108	29	it	it	PRON
ecletica-1322	108	30	capability	capability	NOUN
ecletica-1322	108	31	to	to	PART
ecletica-1322	108	32	inhibit	inhibit	VERB
ecletica-1322	108	33	nitroreductase	nitroreductase	NOUN
ecletica-1322	108	34	rdxa	rdxa	NOUN
ecletica-1322	108	35	proteins	protein	NOUN
ecletica-1322	108	36	than	than	ADP
ecletica-1322	108	37	others	other	NOUN
ecletica-1322	108	38	studied	study	VERB
ecletica-1322	108	39	compound	compound	NOUN
ecletica-1322	108	40	as	as	ADV
ecletica-1322	108	41	well	well	ADV
ecletica-1322	108	42	as	as	ADP
ecletica-1322	108	43	the	the	DET
ecletica-1322	108	44	referenced	referenced	ADJ
ecletica-1322	108	45	drug	drug	NOUN
ecletica-1322	108	46	(	(	PUNCT
ecletica-1322	108	47	compound	compound	VERB
ecletica-1322	108	48	a	a	PRON
ecletica-1322	108	49	)	)	PUNCT
ecletica-1322	108	50	.	.	PUNCT
ecletica-1322	109	1	https://revista.iq.unesp.br/index.php/ecletica	https://revista.iq.unesp.br/index.php/ecletica	PROPN
ecletica-1322	109	2	https://doi.org/10.26850/1678-4618eqj.v47.4.2022.p27-36	https://doi.org/10.26850/1678-4618eqj.v47.4.2022.p27-36	NOUN
ecletica-1322	109	3	original	original	ADJ
ecletica-1322	109	4	article	article	NOUN
ecletica-1322	109	5	revista.iq.unesp.br	revista.iq.unesp.br	PUNCT
ecletica-1322	109	6	33	33	NUM
ecletica-1322	109	7	eclética	eclética	PROPN
ecletica-1322	109	8	química	química	PROPN
ecletica-1322	109	9	journal	journal	PROPN
ecletica-1322	109	10	,	,	PUNCT
ecletica-1322	109	11	vol	vol	NOUN
ecletica-1322	109	12	.	.	PROPN
ecletica-1322	109	13	47	47	NUM
ecletica-1322	109	14	,	,	PUNCT
ecletica-1322	109	15	n.	n.	NOUN
ecletica-1322	109	16	4	4	NUM
ecletica-1322	109	17	,	,	PUNCT
ecletica-1322	109	18	2022	2022	NUM
ecletica-1322	109	19	,	,	PUNCT
ecletica-1322	109	20	27	27	NUM
ecletica-1322	109	21	-	-	SYM
ecletica-1322	109	22	36	36	NUM
ecletica-1322	109	23	issn	issn	NOUN
ecletica-1322	109	24	:	:	PUNCT
ecletica-1322	109	25	1678	1678	NUM
ecletica-1322	109	26	-	-	SYM
ecletica-1322	109	27	4618	4618	NUM
ecletica-1322	109	28	doi	doi	NOUN
ecletica-1322	109	29	:	:	PUNCT
ecletica-1322	109	30	10.26850/1678	10.26850/1678	NUM
ecletica-1322	109	31	-	-	SYM
ecletica-1322	109	32	4618eqj.v47.4.2022.p27	4618eqj.v47.4.2022.p27	NUM
ecletica-1322	109	33	-	-	PUNCT
ecletica-1322	109	34	36	36	NUM
ecletica-1322	109	35	table	table	NOUN
ecletica-1322	109	36	3	3	NUM
ecletica-1322	109	37	.	.	PUNCT
ecletica-1322	109	38	calculated	calculate	VERB
ecletica-1322	109	39	scoring	scoring	NOUN
ecletica-1322	109	40	,	,	PUNCT
ecletica-1322	109	41	residues	residue	NOUN
ecletica-1322	109	42	,	,	PUNCT
ecletica-1322	109	43	inhibition	inhibition	VERB
ecletica-1322	109	44	constant	constant	ADJ
ecletica-1322	109	45	and	and	CCONJ
ecletica-1322	109	46	types	type	NOUN
ecletica-1322	109	47	of	of	ADP
ecletica-1322	109	48	non	non	ADJ
ecletica-1322	109	49	-	-	ADJ
ecletica-1322	109	50	bonding	bonding	ADJ
ecletica-1322	109	51	interactions	interaction	NOUN
ecletica-1322	109	52	between	between	ADP
ecletica-1322	109	53	2hmn	2hmn	PROPN
ecletica-1322	109	54	derivatives	derivative	NOUN
ecletica-1322	109	55	and	and	CCONJ
ecletica-1322	109	56	nitroreductase	nitroreductase	NOUN
ecletica-1322	109	57	rdxa	rdxa	NOUN
ecletica-1322	109	58	protein	protein	NOUN
ecletica-1322	109	59	(	(	PUNCT
ecletica-1322	109	60	pdb	pdb	PROPN
ecletica-1322	109	61	i	i	PROPN
ecletica-1322	109	62	d	d	PROPN
ecletica-1322	109	63	:	:	PUNCT
ecletica-1322	109	64	3qdl	3qdl	NUM
ecletica-1322	109	65	)	)	PUNCT
ecletica-1322	109	66	.	.	PUNCT
ecletica-1322	110	1	compounds	compound	VERB
ecletica-1322	110	2	binding	bind	VERB
ecletica-1322	110	3	affinity	affinity	NOUN
ecletica-1322	110	4	(	(	PUNCT
ecletica-1322	110	5	kj	kj	NOUN
ecletica-1322	110	6	mol–1	mol–1	NOUN
ecletica-1322	110	7	)	)	PUNCT
ecletica-1322	110	8	residue	residue	NOUN
ecletica-1322	110	9	involved	involve	VERB
ecletica-1322	110	10	in	in	ADP
ecletica-1322	110	11	the	the	DET
ecletica-1322	110	12	interaction	interaction	NOUN
ecletica-1322	110	13	inhibition	inhibition	VERB
ecletica-1322	110	14	constant	constant	ADJ
ecletica-1322	110	15	k1	k1	NOUN
ecletica-1322	110	16	(	(	PUNCT
ecletica-1322	110	17	nmol	nmol	PROPN
ecletica-1322	110	18	l–1	l–1	PROPN
ecletica-1322	110	19	)	)	PUNCT
ecletica-1322	110	20	types	type	NOUN
ecletica-1322	110	21	of	of	ADP
ecletica-1322	110	22	nonbonding	nonbonding	NOUN
ecletica-1322	110	23	interaction	interaction	NOUN
ecletica-1322	110	24	involved	involve	VERB
ecletica-1322	110	25	a	a	DET
ecletica-1322	110	26	–	–	SYM
ecletica-1322	110	27	18.8	18.8	NUM
ecletica-1322	110	28	ser	ser	NOUN
ecletica-1322	110	29	199	199	NUM
ecletica-1322	110	30	,	,	PUNCT
ecletica-1322	110	31	ser	ser	NOUN
ecletica-1322	110	32	196	196	NUM
ecletica-1322	110	33	,	,	PUNCT
ecletica-1322	110	34	lys	lys	PROPN
ecletica-1322	110	35	198	198	NUM
ecletica-1322	110	36	,	,	PUNCT
ecletica-1322	110	37	ser	ser	NOUN
ecletica-1322	110	38	18	18	NUM
ecletica-1322	110	39	,	,	PUNCT
ecletica-1322	110	40	arg	arg	VERB
ecletica-1322	110	41	200	200	NUM
ecletica-1322	110	42	6.1	6.1	NUM
ecletica-1322	110	43	conventional	conventional	ADJ
ecletica-1322	110	44	hydrogen	hydrogen	NOUN
ecletica-1322	110	45	bond	bond	NOUN
ecletica-1322	110	46	π	π	NOUN
ecletica-1322	110	47	-	-	NOUN
ecletica-1322	110	48	carbon	carbon	NOUN
ecletica-1322	110	49	,	,	PUNCT
ecletica-1322	110	50	π	π	PROPN
ecletica-1322	110	51	-	-	ADJ
ecletica-1322	110	52	donor	donor	ADJ
ecletica-1322	110	53	hydrogen	hydrogen	NOUN
ecletica-1322	110	54	bond	bond	NOUN
ecletica-1322	110	55	b	b	PROPN
ecletica-1322	110	56	–	–	PUNCT
ecletica-1322	110	57	18.0	18.0	NUM
ecletica-1322	110	58	arg	arg	NOUN
ecletica-1322	110	59	16	16	NUM
ecletica-1322	110	60	,	,	PUNCT
ecletica-1322	110	61	lys	lys	NOUN
ecletica-1322	110	62	198	198	NUM
ecletica-1322	110	63	,	,	PUNCT
ecletica-1322	110	64	arg	arg	VERB
ecletica-1322	110	65	200	200	NUM
ecletica-1322	110	66	,	,	PUNCT
ecletica-1322	110	67	ser	ser	NOUN
ecletica-1322	110	68	18	18	NUM
ecletica-1322	110	69	5.6	5.6	NUM
ecletica-1322	110	70	ππ	ππ	ADP
ecletica-1322	110	71	stacked	stack	VERB
ecletica-1322	110	72	,	,	PUNCT
ecletica-1322	110	73	π	π	PROPN
ecletica-1322	110	74	-	-	PUNCT
ecletica-1322	110	75	alkyl	alkyl	ADJ
ecletica-1322	110	76	c	c	PROPN
ecletica-1322	110	77	c	c	PROPN
ecletica-1322	110	78	–	–	PUNCT
ecletica-1322	110	79	17.2	17.2	NUM
ecletica-1322	110	80	phe	phe	NOUN
ecletica-1322	110	81	3	3	NUM
ecletica-1322	110	82	,	,	PUNCT
ecletica-1322	110	83	leu	leu	PROPN
ecletica-1322	110	84	153	153	NUM
ecletica-1322	110	85	5.2	5.2	NUM
ecletica-1322	110	86	conventional	conventional	ADJ
ecletica-1322	110	87	hydrogen	hydrogen	NOUN
ecletica-1322	110	88	bond	bond	NOUN
ecletica-1322	110	89	,	,	PUNCT
ecletica-1322	110	90	π	π	PROPN
ecletica-1322	110	91	-	-	ADJ
ecletica-1322	110	92	donor	donor	ADJ
ecletica-1322	110	93	hydrogen	hydrogen	NOUN
ecletica-1322	110	94	bond	bond	NOUN
ecletica-1322	110	95	d	d	PROPN
ecletica-1322	110	96	–	–	PUNCT
ecletica-1322	110	97	21.3	21.3	NUM
ecletica-1322	110	98	arg	arg	NOUN
ecletica-1322	110	99	16	16	NUM
ecletica-1322	110	100	,	,	PUNCT
ecletica-1322	110	101	gln	gln	NOUN
ecletica-1322	110	102	17	17	NUM
ecletica-1322	110	103	,	,	PUNCT
ecletica-1322	110	104	ser	ser	NOUN
ecletica-1322	110	105	199	199	NUM
ecletica-1322	110	106	,	,	PUNCT
ecletica-1322	110	107	ser	ser	NOUN
ecletica-1322	110	108	196	196	NUM
ecletica-1322	110	109	,	,	PUNCT
ecletica-1322	110	110	lys	lys	PROPN
ecletica-1322	110	111	198	198	NUM
ecletica-1322	110	112	,	,	PUNCT
ecletica-1322	110	113	ser	ser	NOUN
ecletica-1322	110	114	18	18	NUM
ecletica-1322	110	115	,	,	PUNCT
ecletica-1322	110	116	arg	arg	VERB
ecletica-1322	110	117	200	200	NUM
ecletica-1322	110	118	7.8	7.8	NUM
ecletica-1322	110	119	conventional	conventional	ADJ
ecletica-1322	110	120	hydrogen	hydrogen	NOUN
ecletica-1322	110	121	bond	bond	NOUN
ecletica-1322	110	122	,	,	PUNCT
ecletica-1322	110	123	π	π	PROPN
ecletica-1322	110	124	-	-	NOUN
ecletica-1322	110	125	carbon	carbon	NOUN
ecletica-1322	110	126	π	π	PROPN
ecletica-1322	110	127	-	-	ADJ
ecletica-1322	110	128	donor	donor	ADJ
ecletica-1322	110	129	hydrogen	hydrogen	NOUN
ecletica-1322	110	130	bond	bond	NOUN
ecletica-1322	110	131	e	e	PROPN
ecletica-1322	110	132	–	–	PUNCT
ecletica-1322	110	133	21.3	21.3	NUM
ecletica-1322	110	134	ser	ser	NOUN
ecletica-1322	110	135	199	199	NUM
ecletica-1322	110	136	,	,	PUNCT
ecletica-1322	110	137	ser	ser	NOUN
ecletica-1322	110	138	196	196	NUM
ecletica-1322	110	139	,	,	PUNCT
ecletica-1322	110	140	lys	lys	PROPN
ecletica-1322	110	141	198	198	NUM
ecletica-1322	110	142	,	,	PUNCT
ecletica-1322	110	143	arg	arg	NOUN
ecletica-1322	110	144	16	16	NUM
ecletica-1322	110	145	,	,	PUNCT
ecletica-1322	110	146	ser	ser	NOUN
ecletica-1322	110	147	18	18	NUM
ecletica-1322	110	148	,	,	PUNCT
ecletica-1322	110	149	arg	arg	VERB
ecletica-1322	110	150	200	200	NUM
ecletica-1322	110	151	7.8	7.8	NUM
ecletica-1322	110	152	conventional	conventional	ADJ
ecletica-1322	110	153	hydrogen	hydrogen	NOUN
ecletica-1322	110	154	bond	bond	NOUN
ecletica-1322	110	155	,	,	PUNCT
ecletica-1322	110	156	π	π	PROPN
ecletica-1322	110	157	-	-	NOUN
ecletica-1322	110	158	carbon	carbon	NOUN
ecletica-1322	110	159	π	π	PROPN
ecletica-1322	110	160	-	-	ADJ
ecletica-1322	110	161	donor	donor	ADJ
ecletica-1322	110	162	hydrogen	hydrogen	NOUN
ecletica-1322	110	163	bond	bond	NOUN
ecletica-1322	110	164	f	f	PROPN
ecletica-1322	110	165	–	–	PUNCT
ecletica-1322	110	166	18.4	18.4	NUM
ecletica-1322	110	167	his	his	PRON
ecletica-1322	110	168	17	17	NUM
ecletica-1322	110	169	,	,	PUNCT
ecletica-1322	110	170	ser	ser	NOUN
ecletica-1322	110	171	199	199	NUM
ecletica-1322	110	172	,	,	PUNCT
ecletica-1322	110	173	ser	ser	NOUN
ecletica-1322	110	174	196	196	NUM
ecletica-1322	110	175	,	,	PUNCT
ecletica-1322	110	176	lys	lys	PROPN
ecletica-1322	110	177	198	198	NUM
ecletica-1322	110	178	,	,	PUNCT
ecletica-1322	110	179	ser	ser	NOUN
ecletica-1322	110	180	18	18	NUM
ecletica-1322	110	181	,	,	PUNCT
ecletica-1322	110	182	arg	arg	VERB
ecletica-1322	110	183	200	200	NUM
ecletica-1322	110	184	5.9	5.9	NUM
ecletica-1322	110	185	conventional	conventional	ADJ
ecletica-1322	110	186	hydrogen	hydrogen	NOUN
ecletica-1322	110	187	bond	bond	NOUN
ecletica-1322	110	188	,	,	PUNCT
ecletica-1322	110	189	π	π	NOUN
ecletica-1322	110	190	-	-	ADJ
ecletica-1322	110	191	alkyl	alkyl	ADJ
ecletica-1322	110	192	,	,	PUNCT
ecletica-1322	110	193	π	π	PROPN
ecletica-1322	110	194	-	-	PUNCT
ecletica-1322	110	195	cation	cation	ADJ
ecletica-1322	110	196	carbonhydrogen	carbonhydrogen	NOUN
ecletica-1322	110	197	bond	bond	NOUN
ecletica-1322	110	198	note	note	NOUN
ecletica-1322	110	199	:	:	PUNCT
ecletica-1322	110	200	referenced	reference	VERB
ecletica-1322	110	201	drug	drug	NOUN
ecletica-1322	110	202	=	=	SYM
ecletica-1322	110	203	compound	compound	VERB
ecletica-1322	110	204	a	a	DET
ecletica-1322	110	205	=	=	NOUN
ecletica-1322	110	206	metronidazole	metronidazole	NOUN
ecletica-1322	110	207	.	.	PUNCT
ecletica-1322	111	1	these	these	DET
ecletica-1322	111	2	compounds	compound	NOUN
ecletica-1322	111	3	proved	prove	VERB
ecletica-1322	111	4	to	to	PART
ecletica-1322	111	5	possess	possess	VERB
ecletica-1322	111	6	highest	high	ADJ
ecletica-1322	111	7	tendency	tendency	NOUN
ecletica-1322	111	8	to	to	PART
ecletica-1322	111	9	inhibit	inhibit	VERB
ecletica-1322	111	10	nitroreductase	nitroreductase	NOUN
ecletica-1322	111	11	rdxa	rdxa	NOUN
ecletica-1322	111	12	proteins	protein	NOUN
ecletica-1322	111	13	(	(	PUNCT
ecletica-1322	111	14	pdb	pdb	NOUN
ecletica-1322	111	15	i	i	PROPN
ecletica-1322	111	16	d	d	PROPN
ecletica-1322	111	17	:	:	PUNCT
ecletica-1322	111	18	3qdl	3qdl	NUM
ecletica-1322	111	19	)	)	PUNCT
ecletica-1322	111	20	and	and	CCONJ
ecletica-1322	111	21	may	may	AUX
ecletica-1322	111	22	likely	likely	ADV
ecletica-1322	111	23	be	be	AUX
ecletica-1322	111	24	more	more	ADV
ecletica-1322	111	25	potent	potent	ADJ
ecletica-1322	111	26	than	than	ADP
ecletica-1322	111	27	other	other	ADJ
ecletica-1322	111	28	studied	study	VERB
ecletica-1322	111	29	ligands	ligand	NOUN
ecletica-1322	111	30	.	.	PUNCT
ecletica-1322	112	1	the	the	DET
ecletica-1322	112	2	amino	amino	NOUN
ecletica-1322	112	3	acid	acid	NOUN
ecletica-1322	112	4	residues	residue	NOUN
ecletica-1322	112	5	involved	involve	VERB
ecletica-1322	112	6	in	in	ADP
ecletica-1322	112	7	the	the	DET
ecletica-1322	112	8	interactions	interaction	NOUN
ecletica-1322	112	9	and	and	CCONJ
ecletica-1322	112	10	the	the	DET
ecletica-1322	112	11	types	type	NOUN
ecletica-1322	112	12	of	of	ADP
ecletica-1322	112	13	nonbonding	nonbonding	NOUN
ecletica-1322	112	14	interactions	interaction	NOUN
ecletica-1322	112	15	involved	involve	VERB
ecletica-1322	112	16	are	be	AUX
ecletica-1322	112	17	as	as	SCONJ
ecletica-1322	112	18	displayed	display	VERB
ecletica-1322	112	19	in	in	ADP
ecletica-1322	112	20	fig	fig	NOUN
ecletica-1322	112	21	.	.	PUNCT
ecletica-1322	113	1	4	4	NUM
ecletica-1322	113	2	and	and	CCONJ
ecletica-1322	113	3	tab	tab	NOUN
ecletica-1322	113	4	.	.	PUNCT
ecletica-1322	114	1	3	3	X
ecletica-1322	114	2	.	.	X
ecletica-1322	114	3	furthermore	furthermore	ADV
ecletica-1322	114	4	,	,	PUNCT
ecletica-1322	114	5	compounds	compound	NOUN
ecletica-1322	114	6	d	d	NOUN
ecletica-1322	114	7	and	and	CCONJ
ecletica-1322	114	8	e	e	NOUN
ecletica-1322	114	9	’s	’s	NOUN
ecletica-1322	114	10	adme	adme	VERB
ecletica-1322	114	11	features	feature	VERB
ecletica-1322	114	12	with	with	ADP
ecletica-1322	114	13	the	the	DET
ecletica-1322	114	14	best	well	ADV
ecletica-1322	114	15	efficient	efficient	ADJ
ecletica-1322	114	16	calculated	calculate	VERB
ecletica-1322	114	17	binding	bind	VERB
ecletica-1322	114	18	affinity	affinity	NOUN
ecletica-1322	114	19	were	be	AUX
ecletica-1322	114	20	comparable	comparable	ADJ
ecletica-1322	114	21	with	with	ADP
ecletica-1322	114	22	the	the	DET
ecletica-1322	114	23	standard	standard	ADJ
ecletica-1322	114	24	metronidazole	metronidazole	NOUN
ecletica-1322	114	25	(	(	PUNCT
ecletica-1322	114	26	tab	tab	NOUN
ecletica-1322	114	27	.	.	PUNCT
ecletica-1322	114	28	4	4	NUM
ecletica-1322	114	29	)	)	PUNCT
ecletica-1322	114	30	.	.	PUNCT
ecletica-1322	115	1	table	table	NOUN
ecletica-1322	115	2	4	4	NUM
ecletica-1322	115	3	.	.	PUNCT
ecletica-1322	115	4	drug	drug	NOUN
ecletica-1322	115	5	-	-	PUNCT
ecletica-1322	115	6	likeness	likeness	NOUN
ecletica-1322	115	7	prediction	prediction	NOUN
ecletica-1322	115	8	.	.	PUNCT
ecletica-1322	116	1	compounds	compound	VERB
ecletica-1322	116	2	molecular	molecular	ADJ
ecletica-1322	116	3	weight	weight	NOUN
ecletica-1322	116	4	log	log	NOUN
ecletica-1322	116	5	p	p	PROPN
ecletica-1322	116	6	hbd	hbd	PROPN
ecletica-1322	116	7	hba	hba	PROPN
ecletica-1322	116	8	violations	violation	VERB
ecletica-1322	116	9	a	a	DET
ecletica-1322	116	10	171.156	171.156	NUM
ecletica-1322	116	11	0.42	0.42	NUM
ecletica-1322	116	12	1	1	NUM
ecletica-1322	116	13	5	5	NUM
ecletica-1322	116	14	0	0	NUM
ecletica-1322	116	15	b	b	X
ecletica-1322	116	16	155.157	155.157	NUM
ecletica-1322	116	17	1.28	1.28	NUM
ecletica-1322	116	18	0	0	NUM
ecletica-1322	116	19	4	4	NUM
ecletica-1322	116	20	0	0	NUM
ecletica-1322	117	1	c	c	NOUN
ecletica-1322	117	2	277.348	277.348	NUM
ecletica-1322	117	3	3.45	3.45	NUM
ecletica-1322	117	4	0	0	NUM
ecletica-1322	117	5	5	5	NUM
ecletica-1322	117	6	0	0	NUM
ecletica-1322	117	7	d	d	ADP
ecletica-1322	117	8	199.166	199.166	NUM
ecletica-1322	118	1	0.70	0.70	NUM
ecletica-1322	118	2	1	1	NUM
ecletica-1322	118	3	5	5	NUM
ecletica-1322	118	4	0	0	NUM
ecletica-1322	118	5	e	e	NOUN
ecletica-1322	118	6	200.154	200.154	NUM
ecletica-1322	118	7	0.59	0.59	NUM
ecletica-1322	118	8	0	0	NUM
ecletica-1322	118	9	5	5	NUM
ecletica-1322	118	10	0	0	NUM
ecletica-1322	118	11	f	f	PROPN
ecletica-1322	118	12	185.183	185.183	NUM
ecletica-1322	118	13	0.78	0.78	NUM
ecletica-1322	118	14	0	0	NUM
ecletica-1322	118	15	5	5	NUM
ecletica-1322	118	16	0	0	NUM
ecletica-1322	118	17	the	the	PRON
ecletica-1322	118	18	higher	high	ADJ
ecletica-1322	118	19	the	the	DET
ecletica-1322	118	20	hia	hia	PROPN
ecletica-1322	118	21	,	,	PUNCT
ecletica-1322	118	22	the	the	PRON
ecletica-1322	118	23	better	well	ADJ
ecletica-1322	118	24	the	the	DET
ecletica-1322	118	25	compound	compound	NOUN
ecletica-1322	118	26	’s	’s	PART
ecletica-1322	118	27	tendency	tendency	NOUN
ecletica-1322	118	28	to	to	PART
ecletica-1322	118	29	be	be	AUX
ecletica-1322	118	30	absorbed	absorb	VERB
ecletica-1322	118	31	upon	upon	SCONJ
ecletica-1322	118	32	oral	oral	ADJ
ecletica-1322	118	33	administration	administration	NOUN
ecletica-1322	118	34	(	(	PUNCT
ecletica-1322	118	35	oyebamiji	oyebamiji	PROPN
ecletica-1322	118	36	et	et	PROPN
ecletica-1322	118	37	al	al	PROPN
ecletica-1322	118	38	.	.	PROPN
ecletica-1322	118	39	,	,	PUNCT
ecletica-1322	118	40	2020	2020	NUM
ecletica-1322	118	41	)	)	PUNCT
ecletica-1322	118	42	.	.	PUNCT
ecletica-1322	119	1	as	as	SCONJ
ecletica-1322	119	2	observed	observe	VERB
ecletica-1322	119	3	in	in	ADP
ecletica-1322	119	4	tab	tab	NOUN
ecletica-1322	119	5	.	.	PUNCT
ecletica-1322	120	1	5	5	NUM
ecletica-1322	120	2	,	,	PUNCT
ecletica-1322	120	3	the	the	DET
ecletica-1322	120	4	values	value	NOUN
ecletica-1322	120	5	of	of	ADP
ecletica-1322	120	6	hia	hia	PROPN
ecletica-1322	120	7	for	for	ADP
ecletica-1322	120	8	the	the	DET
ecletica-1322	120	9	studied	study	VERB
ecletica-1322	120	10	compounds	compound	NOUN
ecletica-1322	120	11	are	be	AUX
ecletica-1322	120	12	positive	positive	ADJ
ecletica-1322	120	13	and	and	CCONJ
ecletica-1322	120	14	correlated	correlate	VERB
ecletica-1322	120	15	with	with	ADP
ecletica-1322	120	16	the	the	DET
ecletica-1322	120	17	standard	standard	NOUN
ecletica-1322	120	18	.	.	PUNCT
ecletica-1322	121	1	this	this	PRON
ecletica-1322	121	2	further	far	ADV
ecletica-1322	121	3	proved	prove	VERB
ecletica-1322	121	4	that	that	SCONJ
ecletica-1322	121	5	the	the	DET
ecletica-1322	121	6	selected	select	VERB
ecletica-1322	121	7	compounds	compound	NOUN
ecletica-1322	121	8	have	have	VERB
ecletica-1322	121	9	capacities	capacity	NOUN
ecletica-1322	121	10	to	to	PART
ecletica-1322	121	11	be	be	AUX
ecletica-1322	121	12	absorbed	absorb	VERB
ecletica-1322	121	13	in	in	ADP
ecletica-1322	121	14	the	the	DET
ecletica-1322	121	15	intestine	intestine	NOUN
ecletica-1322	121	16	.	.	PUNCT
ecletica-1322	122	1	the	the	DET
ecletica-1322	122	2	ability	ability	NOUN
ecletica-1322	122	3	to	to	PART
ecletica-1322	122	4	cross	cross	VERB
ecletica-1322	122	5	the	the	DET
ecletica-1322	122	6	bbb	bbb	NOUN
ecletica-1322	122	7	for	for	ADP
ecletica-1322	122	8	compounds	compound	NOUN
ecletica-1322	122	9	d	d	NOUN
ecletica-1322	122	10	and	and	CCONJ
ecletica-1322	122	11	e	e	NOUN
ecletica-1322	122	12	are	be	AUX
ecletica-1322	122	13	also	also	ADV
ecletica-1322	122	14	closer	close	ADJ
ecletica-1322	122	15	to	to	ADP
ecletica-1322	122	16	the	the	DET
ecletica-1322	122	17	existing	exist	VERB
ecletica-1322	122	18	standard	standard	ADJ
ecletica-1322	122	19	drug	drug	NOUN
ecletica-1322	122	20	(	(	PUNCT
ecletica-1322	122	21	metronidazole	metronidazole	NOUN
ecletica-1322	122	22	)	)	PUNCT
ecletica-1322	122	23	,	,	PUNCT
ecletica-1322	122	24	while	while	SCONJ
ecletica-1322	122	25	the	the	DET
ecletica-1322	122	26	molar	molar	ADJ
ecletica-1322	122	27	solubility	solubility	NOUN
ecletica-1322	122	28	in	in	ADP
ecletica-1322	122	29	aqueous	aqueous	ADJ
ecletica-1322	122	30	state	state	NOUN
ecletica-1322	122	31	(	(	PUNCT
ecletica-1322	122	32	log	log	NOUN
ecletica-1322	122	33	s	s	PART
ecletica-1322	122	34	)	)	PUNCT
ecletica-1322	122	35	values	value	NOUN
ecletica-1322	122	36	of	of	ADP
ecletica-1322	122	37	the	the	DET
ecletica-1322	122	38	selected	select	VERB
ecletica-1322	122	39	compounds	compound	NOUN
ecletica-1322	122	40	and	and	CCONJ
ecletica-1322	122	41	standards	standard	NOUN
ecletica-1322	122	42	fall	fall	VERB
ecletica-1322	122	43	within	within	ADP
ecletica-1322	122	44	the	the	DET
ecletica-1322	122	45	recommended	recommend	VERB
ecletica-1322	122	46	range	range	NOUN
ecletica-1322	122	47	of	of	ADP
ecletica-1322	122	48	1	1	NUM
ecletica-1322	122	49	to	to	PART
ecletica-1322	122	50	5	5	NUM
ecletica-1322	122	51	(	(	PUNCT
ecletica-1322	122	52	ibrahim	ibrahim	NOUN
ecletica-1322	122	53	et	et	PROPN
ecletica-1322	122	54	al	al	PROPN
ecletica-1322	122	55	.	.	PROPN
ecletica-1322	122	56	,	,	PUNCT
ecletica-1322	122	57	2018	2018	NUM
ecletica-1322	122	58	)	)	PUNCT
ecletica-1322	122	59	.	.	PUNCT
ecletica-1322	123	1	the	the	DET
ecletica-1322	123	2	observed	observe	VERB
ecletica-1322	123	3	adme	adme	NOUN
ecletica-1322	123	4	factors	factor	NOUN
ecletica-1322	123	5	indicate	indicate	VERB
ecletica-1322	123	6	that	that	SCONJ
ecletica-1322	123	7	the	the	DET
ecletica-1322	123	8	selected	select	VERB
ecletica-1322	123	9	compounds	compound	NOUN
ecletica-1322	123	10	and	and	CCONJ
ecletica-1322	123	11	the	the	DET
ecletica-1322	123	12	standards	standard	NOUN
ecletica-1322	123	13	have	have	VERB
ecletica-1322	123	14	better	well	ADJ
ecletica-1322	123	15	absorption	absorption	NOUN
ecletica-1322	123	16	and	and	CCONJ
ecletica-1322	123	17	distribution	distribution	NOUN
ecletica-1322	123	18	properties	property	NOUN
ecletica-1322	123	19	.	.	PUNCT
ecletica-1322	124	1	the	the	DET
ecletica-1322	124	2	caco-2	caco-2	NUM
ecletica-1322	124	3	permeability	permeability	NOUN
ecletica-1322	124	4	reveals	reveal	VERB
ecletica-1322	124	5	the	the	DET
ecletica-1322	124	6	permeability	permeability	NOUN
ecletica-1322	124	7	on	on	ADP
ecletica-1322	124	8	lipid	lipid	ADJ
ecletica-1322	124	9	absorption	absorption	NOUN
ecletica-1322	124	10	and	and	CCONJ
ecletica-1322	124	11	metabolism	metabolism	NOUN
ecletica-1322	124	12	of	of	ADP
ecletica-1322	124	13	the	the	DET
ecletica-1322	124	14	studied	study	VERB
ecletica-1322	124	15	compounds	compound	NOUN
ecletica-1322	124	16	(	(	PUNCT
ecletica-1322	124	17	semire	semire	NOUN
ecletica-1322	124	18	et	et	PROPN
ecletica-1322	124	19	al	al	PROPN
ecletica-1322	124	20	.	.	PROPN
ecletica-1322	124	21	,	,	PUNCT
ecletica-1322	124	22	2017	2017	NUM
ecletica-1322	124	23	)	)	PUNCT
ecletica-1322	124	24	.	.	PUNCT
ecletica-1322	125	1	the	the	DET
ecletica-1322	125	2	probability	probability	NOUN
ecletica-1322	125	3	of	of	ADP
ecletica-1322	125	4	this	this	PRON
ecletica-1322	125	5	was	be	AUX
ecletica-1322	125	6	higher	high	ADJ
ecletica-1322	125	7	in	in	ADP
ecletica-1322	125	8	compound	compound	NOUN
ecletica-1322	125	9	d	d	NOUN
ecletica-1322	125	10	,	,	PUNCT
ecletica-1322	125	11	but	but	CCONJ
ecletica-1322	125	12	little	little	ADJ
ecletica-1322	125	13	lower	low	ADJ
ecletica-1322	125	14	than	than	ADP
ecletica-1322	125	15	the	the	DET
ecletica-1322	125	16	standard	standard	NOUN
ecletica-1322	125	17	in	in	ADP
ecletica-1322	125	18	the	the	DET
ecletica-1322	125	19	ligand	ligand	NOUN
ecletica-1322	125	20	e.	e.	PROPN
ecletica-1322	125	21	also	also	ADV
ecletica-1322	125	22	,	,	PUNCT
ecletica-1322	125	23	in	in	ADP
ecletica-1322	125	24	terms	term	NOUN
ecletica-1322	125	25	of	of	ADP
ecletica-1322	125	26	metabolic	metabolic	NOUN
ecletica-1322	125	27	activities	activity	NOUN
ecletica-1322	125	28	of	of	ADP
ecletica-1322	125	29	the	the	DET
ecletica-1322	125	30	selected	select	VERB
ecletica-1322	125	31	ligands	ligand	NOUN
ecletica-1322	125	32	,	,	PUNCT
ecletica-1322	125	33	compounds	compound	NOUN
ecletica-1322	125	34	d	d	NOUN
ecletica-1322	125	35	and	and	CCONJ
ecletica-1322	125	36	e	e	NOUN
ecletica-1322	125	37	are	be	AUX
ecletica-1322	125	38	non	non	ADJ
ecletica-1322	125	39	-	-	NOUN
ecletica-1322	125	40	inhibitors	inhibitor	NOUN
ecletica-1322	125	41	and	and	CCONJ
ecletica-1322	125	42	nonsubstrates	nonsubstrate	NOUN
ecletica-1322	125	43	for	for	ADP
ecletica-1322	125	44	microsomal	microsomal	ADJ
ecletica-1322	125	45	enzymes	enzyme	NOUN
ecletica-1322	125	46	(	(	PUNCT
ecletica-1322	125	47	cyp450	cyp450	NOUN
ecletica-1322	125	48	2c9	2c9	NUM
ecletica-1322	125	49	,	,	PUNCT
ecletica-1322	125	50	cyp450	cyp450	NOUN
ecletica-1322	125	51	2d6	2d6	NUM
ecletica-1322	125	52	and	and	CCONJ
ecletica-1322	125	53	cyp450	cyp450	NOUN
ecletica-1322	125	54	2c19	2c19	NOUN
ecletica-1322	125	55	)	)	PUNCT
ecletica-1322	125	56	,	,	PUNCT
ecletica-1322	125	57	similar	similar	ADJ
ecletica-1322	125	58	to	to	ADP
ecletica-1322	125	59	the	the	DET
ecletica-1322	125	60	standard	standard	NOUN
ecletica-1322	125	61	.	.	PUNCT
ecletica-1322	126	1	a	a	DET
ecletica-1322	126	2	noninhibitor	noninhibitor	NOUN
ecletica-1322	126	3	of	of	ADP
ecletica-1322	126	4	cyp450	cyp450	NOUN
ecletica-1322	126	5	means	mean	VERB
ecletica-1322	126	6	that	that	SCONJ
ecletica-1322	126	7	the	the	DET
ecletica-1322	126	8	molecule	molecule	NOUN
ecletica-1322	126	9	will	will	AUX
ecletica-1322	126	10	not	not	PART
ecletica-1322	126	11	hamper	hamper	VERB
ecletica-1322	126	12	the	the	DET
ecletica-1322	126	13	biotransformation	biotransformation	NOUN
ecletica-1322	126	14	of	of	ADP
ecletica-1322	126	15	the	the	DET
ecletica-1322	126	16	drugs	drug	NOUN
ecletica-1322	126	17	metabolized	metabolize	VERB
ecletica-1322	126	18	by	by	ADP
ecletica-1322	126	19	cyp450	cyp450	NOUN
ecletica-1322	126	20	enzyme	enzyme	NOUN
ecletica-1322	126	21	(	(	PUNCT
ecletica-1322	126	22	nisha	nisha	PROPN
ecletica-1322	126	23	et	et	PROPN
ecletica-1322	126	24	al	al	PROPN
ecletica-1322	126	25	.	.	PROPN
ecletica-1322	126	26	,	,	PUNCT
ecletica-1322	126	27	2016	2016	NUM
ecletica-1322	126	28	)	)	PUNCT
ecletica-1322	126	29	.	.	PUNCT
ecletica-1322	127	1	https://revista.iq.unesp.br/index.php/ecletica	https://revista.iq.unesp.br/index.php/ecletica	PROPN
ecletica-1322	127	2	https://doi.org/10.26850/1678-4618eqj.v47.4.2022.p27-36	https://doi.org/10.26850/1678-4618eqj.v47.4.2022.p27-36	NOUN
ecletica-1322	127	3	original	original	ADJ
ecletica-1322	127	4	article	article	NOUN
ecletica-1322	127	5	revista.iq.unesp.br	revista.iq.unesp.br	PUNCT
ecletica-1322	127	6	34	34	NUM
ecletica-1322	127	7	eclética	eclética	PROPN
ecletica-1322	127	8	química	química	PROPN
ecletica-1322	127	9	journal	journal	PROPN
ecletica-1322	127	10	,	,	PUNCT
ecletica-1322	127	11	vol	vol	NOUN
ecletica-1322	127	12	.	.	PROPN
ecletica-1322	127	13	47	47	NUM
ecletica-1322	127	14	,	,	PUNCT
ecletica-1322	127	15	n.	n.	NOUN
ecletica-1322	127	16	4	4	NUM
ecletica-1322	127	17	,	,	PUNCT
ecletica-1322	127	18	2022	2022	NUM
ecletica-1322	127	19	,	,	PUNCT
ecletica-1322	127	20	27	27	NUM
ecletica-1322	127	21	-	-	SYM
ecletica-1322	127	22	36	36	NUM
ecletica-1322	127	23	issn	issn	NOUN
ecletica-1322	127	24	:	:	PUNCT
ecletica-1322	127	25	1678	1678	NUM
ecletica-1322	127	26	-	-	SYM
ecletica-1322	127	27	4618	4618	NUM
ecletica-1322	127	28	doi	doi	NOUN
ecletica-1322	127	29	:	:	PUNCT
ecletica-1322	127	30	10.26850/1678	10.26850/1678	NUM
ecletica-1322	127	31	-	-	SYM
ecletica-1322	127	32	4618eqj.v47.4.2022.p27	4618eqj.v47.4.2022.p27	NUM
ecletica-1322	127	33	-	-	PUNCT
ecletica-1322	127	34	36	36	NUM
ecletica-1322	127	35	table	table	NOUN
ecletica-1322	127	36	5	5	NUM
ecletica-1322	127	37	.	.	PUNCT
ecletica-1322	127	38	predicted	predict	VERB
ecletica-1322	127	39	adme	adme	NOUN
ecletica-1322	127	40	properties	property	NOUN
ecletica-1322	127	41	of	of	ADP
ecletica-1322	127	42	the	the	DET
ecletica-1322	127	43	studied	study	VERB
ecletica-1322	127	44	compounds	compound	NOUN
ecletica-1322	127	45	.	.	PUNCT
ecletica-1322	128	1	compound	compound	NOUN
ecletica-1322	128	2	d	d	PROPN
ecletica-1322	128	3	compound	compound	NOUN
ecletica-1322	128	4	e	e	NOUN
ecletica-1322	128	5	compound	compound	VERB
ecletica-1322	128	6	a	a	DET
ecletica-1322	128	7	(	(	PUNCT
ecletica-1322	128	8	metronidazole	metronidazole	NOUN
ecletica-1322	128	9	)	)	PUNCT
ecletica-1322	128	10	mode	mode	NOUN
ecletica-1322	128	11	result	result	NOUN
ecletica-1322	128	12	probability	probability	NOUN
ecletica-1322	128	13	result	result	NOUN
ecletica-1322	128	14	probability	probability	NOUN
ecletica-1322	128	15	result	result	NOUN
ecletica-1322	128	16	probability	probability	NOUN
ecletica-1322	128	17	blood	blood	NOUN
ecletica-1322	128	18	-	-	PUNCT
ecletica-1322	128	19	brain	brain	NOUN
ecletica-1322	128	20	barrier	barrier	NOUN
ecletica-1322	128	21	bbb+	bbb+	PROPN
ecletica-1322	128	22	0.114253	0.114253	NUM
ecletica-1322	128	23	bbb+	bbb+	ADJ
ecletica-1322	128	24	0.12801	0.12801	NUM
ecletica-1322	128	25	bbb+	bbb+	ADV
ecletica-1322	128	26	0.173454	0.173454	NUM
ecletica-1322	128	27	human	human	ADJ
ecletica-1322	128	28	intestinal	intestinal	ADJ
ecletica-1322	128	29	absorption	absorption	NOUN
ecletica-1322	128	30	hia+	hia+	NOUN
ecletica-1322	128	31	high	high	ADV
ecletica-1322	128	32	hia+	hia+	PROPN
ecletica-1322	128	33	high	high	ADV
ecletica-1322	128	34	hia+	hia+	X
ecletica-1322	128	35	high	high	ADJ
ecletica-1322	128	36	caco-2	caco-2	NUM
ecletica-1322	128	37	permeability	permeability	NOUN
ecletica-1322	128	38	caco-2	caco-2	NUM
ecletica-1322	128	39	high	high	ADJ
ecletica-1322	128	40	caco2	caco2	NOUN
ecletica-1322	128	41	+	+	X
ecletica-1322	128	42	high	high	ADJ
ecletica-1322	128	43	caco2	caco2	NOUN
ecletica-1322	128	44	+	+	X
ecletica-1322	128	45	high	high	ADJ
ecletica-1322	128	46	log	log	NOUN
ecletica-1322	128	47	s	s	PART
ecletica-1322	128	48	esol	esol	NOUN
ecletica-1322	128	49	–	–	PUNCT
ecletica-1322	128	50	0.67	0.67	NUM
ecletica-1322	128	51	esol	esol	NOUN
ecletica-1322	128	52	–	–	PUNCT
ecletica-1322	128	53	0.86	0.86	NUM
ecletica-1322	128	54	esol	esol	NOUN
ecletica-1322	128	55	–	–	PUNCT
ecletica-1322	128	56	1.00	1.00	NUM
ecletica-1322	128	57	solubility	solubility	NOUN
ecletica-1322	128	58	(	(	PUNCT
ecletica-1322	128	59	mg	mg	PROPN
ecletica-1322	128	60	/	/	SYM
ecletica-1322	128	61	ml	ml	NOUN
ecletica-1322	128	62	)	)	PUNCT
ecletica-1322	128	63	very	very	ADV
ecletica-1322	128	64	soluble	soluble	ADJ
ecletica-1322	128	65	4.32	4.32	NUM
ecletica-1322	128	66	+	+	SYM
ecletica-1322	128	67	01	01	NUM
ecletica-1322	128	68	very	very	ADV
ecletica-1322	128	69	soluble	soluble	ADJ
ecletica-1322	128	70	2.76	2.76	NUM
ecletica-1322	128	71	+	+	NOUN
ecletica-1322	128	72	01	01	NUM
ecletica-1322	128	73	very	very	ADV
ecletica-1322	128	74	soluble	soluble	ADJ
ecletica-1322	128	75	1.72	1.72	NUM
ecletica-1322	128	76	+	+	SYM
ecletica-1322	128	77	01	01	NUM
ecletica-1322	128	78	log	log	NOUN
ecletica-1322	128	79	s	s	PROPN
ecletica-1322	128	80	ali	ali	PROPN
ecletica-1322	128	81	–	–	PUNCT
ecletica-1322	128	82	1.00	1.00	NUM
ecletica-1322	128	83	ali	ali	X
ecletica-1322	128	84	–	–	PUNCT
ecletica-1322	128	85	1.49	1.49	NUM
ecletica-1322	128	86	ali	ali	NOUN
ecletica-1322	128	87	–	–	PUNCT
ecletica-1322	128	88	1.29	1.29	NUM
ecletica-1322	128	89	p	p	NOUN
ecletica-1322	128	90	-	-	PUNCT
ecletica-1322	128	91	gp	gp	NOUN
ecletica-1322	128	92	substrate	substrate	NOUN
ecletica-1322	128	93	substrate	substrate	NOUN
ecletica-1322	128	94	no	no	DET
ecletica-1322	128	95	substrate	substrate	NOUN
ecletica-1322	128	96	no	no	DET
ecletica-1322	128	97	substrate	substrate	NOUN
ecletica-1322	128	98	no	no	DET
ecletica-1322	128	99	log	log	NOUN
ecletica-1322	129	1	p	p	PROPN
ecletica-1322	129	2	ilogp	ilogp	NOUN
ecletica-1322	129	3	0.77	0.77	NUM
ecletica-1322	129	4	ilogp	ilogp	NOUN
ecletica-1322	129	5	0.59	0.59	NUM
ecletica-1322	129	6	ilogp	ilogp	NOUN
ecletica-1322	129	7	1.16	1.16	NUM
ecletica-1322	129	8	lipinski	lipinski	PROPN
ecletica-1322	129	9	’s	’s	PART
ecletica-1322	129	10	rule	rule	NOUN
ecletica-1322	130	1	yes	yes	INTJ
ecletica-1322	130	2	yes	yes	INTJ
ecletica-1322	131	1	yes	yes	INTJ
ecletica-1322	131	2	cyp450	cyp450	NOUN
ecletica-1322	131	3	2d6	2d6	NOUN
ecletica-1322	131	4	substrate	substrate	NOUN
ecletica-1322	131	5	noninhibitor	noninhibitor	NOUN
ecletica-1322	131	6	no	no	DET
ecletica-1322	131	7	substrate	substrate	NOUN
ecletica-1322	131	8	no	no	DET
ecletica-1322	131	9	noninhibitor	noninhibitor	NOUN
ecletica-1322	131	10	no	no	DET
ecletica-1322	131	11	cyp450	cyp450	NOUN
ecletica-1322	131	12	2c9	2c9	NUM
ecletica-1322	131	13	inhibitor	inhibitor	NOUN
ecletica-1322	131	14	noninhibitor	noninhibitor	NOUN
ecletica-1322	131	15	no	no	DET
ecletica-1322	131	16	noninhibitor	noninhibitor	NOUN
ecletica-1322	131	17	no	no	DET
ecletica-1322	131	18	noninhibitor	noninhibitor	NOUN
ecletica-1322	131	19	no	no	DET
ecletica-1322	131	20	cyp450	cyp450	NOUN
ecletica-1322	131	21	2d6	2d6	NOUN
ecletica-1322	131	22	inhibitor	inhibitor	NOUN
ecletica-1322	131	23	noninhibitor	noninhibitor	NOUN
ecletica-1322	131	24	no	no	DET
ecletica-1322	131	25	noninhibitor	noninhibitor	NOUN
ecletica-1322	131	26	no	no	DET
ecletica-1322	131	27	noninhibitor	noninhibitor	NOUN
ecletica-1322	131	28	no	no	DET
ecletica-1322	131	29	cyp450	cyp450	NOUN
ecletica-1322	131	30	2c19	2c19	NOUN
ecletica-1322	131	31	inhibitor	inhibitor	NOUN
ecletica-1322	131	32	noninhibitor	noninhibitor	NOUN
ecletica-1322	131	33	no	no	DET
ecletica-1322	131	34	noninhibitor	noninhibitor	NOUN
ecletica-1322	131	35	no	no	DET
ecletica-1322	131	36	noninhibitor	noninhibitor	NOUN
ecletica-1322	131	37	no	no	DET
ecletica-1322	131	38	cyp450	cyp450	NOUN
ecletica-1322	131	39	3a4	3a4	NUM
ecletica-1322	131	40	inhibitor	inhibitor	NOUN
ecletica-1322	131	41	inhibitor	inhibitor	NOUN
ecletica-1322	131	42	no	no	DET
ecletica-1322	131	43	inhibitor	inhibitor	NOUN
ecletica-1322	131	44	no	no	DET
ecletica-1322	131	45	inhibitor	inhibitor	NOUN
ecletica-1322	131	46	no	no	DET
ecletica-1322	131	47	cyp450	cyp450	NOUN
ecletica-1322	131	48	3a4	3a4	NUM
ecletica-1322	131	49	substrate	substrate	NOUN
ecletica-1322	131	50	substrate	substrate	NOUN
ecletica-1322	131	51	no	no	DET
ecletica-1322	131	52	substrate	substrate	NOUN
ecletica-1322	131	53	substrate	substrate	NOUN
ecletica-1322	131	54	substrate	substrate	NOUN
ecletica-1322	131	55	substrate	substrate	NOUN
ecletica-1322	131	56	synthetic	synthetic	ADJ
ecletica-1322	131	57	accessibility	accessibility	NOUN
ecletica-1322	131	58	2.23	2.23	NUM
ecletica-1322	131	59	2.53	2.53	NUM
ecletica-1322	131	60	2.30	2.30	NUM
ecletica-1322	131	61	ghose	ghose	NOUN
ecletica-1322	131	62	0	0	NUM
ecletica-1322	131	63	0	0	NUM
ecletica-1322	131	64	0	0	NUM
ecletica-1322	131	65	vegar	vegar	NOUN
ecletica-1322	131	66	0	0	NUM
ecletica-1322	131	67	0	0	NUM
ecletica-1322	131	68	0	0	NUM
ecletica-1322	131	69	pain	pain	NOUN
ecletica-1322	131	70	0	0	NUM
ecletica-1322	131	71	,	,	PUNCT
ecletica-1322	131	72	alert	alert	VERB
ecletica-1322	131	73	0.12801	0.12801	NUM
ecletica-1322	131	74	0	0	NUM
ecletica-1322	131	75	,	,	PUNCT
ecletica-1322	131	76	alert	alert	ADJ
ecletica-1322	131	77	4	4	NUM
ecletica-1322	131	78	.	.	PUNCT
ecletica-1322	131	79	conclusions	conclusion	NOUN
ecletica-1322	131	80	this	this	DET
ecletica-1322	131	81	study	study	NOUN
ecletica-1322	131	82	was	be	AUX
ecletica-1322	131	83	carried	carry	VERB
ecletica-1322	131	84	out	out	ADP
ecletica-1322	131	85	to	to	PART
ecletica-1322	131	86	determine	determine	VERB
ecletica-1322	131	87	the	the	DET
ecletica-1322	131	88	effects	effect	NOUN
ecletica-1322	131	89	of	of	ADP
ecletica-1322	131	90	substituents	substituent	NOUN
ecletica-1322	131	91	:	:	PUNCT
ecletica-1322	131	92	–	–	PUNCT
ecletica-1322	131	93	oh	oh	INTJ
ecletica-1322	131	94	,	,	PUNCT
ecletica-1322	131	95	h	h	NOUN
ecletica-1322	131	96	,	,	PUNCT
ecletica-1322	131	97	–	–	PUNCT
ecletica-1322	131	98	sph	sph	NOUN
ecletica-1322	131	99	,	,	PUNCT
ecletica-1322	131	100	–	–	PUNCT
ecletica-1322	131	101	cooh	cooh	NOUN
ecletica-1322	131	102	,	,	PUNCT
ecletica-1322	131	103	–	–	PUNCT
ecletica-1322	131	104	no2	no2	NOUN
ecletica-1322	131	105	and	and	CCONJ
ecletica-1322	131	106	–	–	PUNCT
ecletica-1322	131	107	och3	och3	ADJ
ecletica-1322	131	108	on	on	ADP
ecletica-1322	131	109	the	the	DET
ecletica-1322	131	110	chemical	chemical	NOUN
ecletica-1322	131	111	activities	activity	NOUN
ecletica-1322	131	112	and	and	CCONJ
ecletica-1322	131	113	interactions	interaction	NOUN
ecletica-1322	131	114	of	of	ADP
ecletica-1322	131	115	six	six	NUM
ecletica-1322	131	116	nitroimidazole	nitroimidazole	ADJ
ecletica-1322	131	117	derivatives	derivative	NOUN
ecletica-1322	131	118	on	on	ADP
ecletica-1322	131	119	the	the	DET
ecletica-1322	131	120	target	target	NOUN
ecletica-1322	131	121	nitroreductase	nitroreductase	NOUN
ecletica-1322	131	122	rdxa	rdxa	NOUN
ecletica-1322	131	123	protein	protein	NOUN
ecletica-1322	131	124	(	(	PUNCT
ecletica-1322	131	125	pdb	pdb	PROPN
ecletica-1322	131	126	i	i	PROPN
ecletica-1322	131	127	d	d	PROPN
ecletica-1322	131	128	:	:	PUNCT
ecletica-1322	131	129	3qdl	3qdl	NUM
ecletica-1322	131	130	)	)	PUNCT
ecletica-1322	131	131	for	for	ADP
ecletica-1322	131	132	the	the	DET
ecletica-1322	131	133	treatment	treatment	NOUN
ecletica-1322	131	134	of	of	ADP
ecletica-1322	131	135	h.	h.	PROPN
ecletica-1322	131	136	pylori	pylori	ADJ
ecletica-1322	131	137	infection	infection	NOUN
ecletica-1322	131	138	.	.	PUNCT
ecletica-1322	132	1	the	the	DET
ecletica-1322	132	2	nonbonding	nonbonding	NOUN
ecletica-1322	132	3	interactions	interaction	NOUN
ecletica-1322	132	4	and	and	CCONJ
ecletica-1322	132	5	the	the	DET
ecletica-1322	132	6	calculated	calculated	ADJ
ecletica-1322	132	7	binding	bind	VERB
ecletica-1322	132	8	affinities	affinity	NOUN
ecletica-1322	132	9	that	that	PRON
ecletica-1322	132	10	exist	exist	VERB
ecletica-1322	132	11	between	between	ADP
ecletica-1322	132	12	the	the	DET
ecletica-1322	132	13	six	six	NUM
ecletica-1322	132	14	compounds	compound	NOUN
ecletica-1322	132	15	and	and	CCONJ
ecletica-1322	132	16	the	the	DET
ecletica-1322	132	17	nitroreductase	nitroreductase	NOUN
ecletica-1322	132	18	rdxa	rdxa	NOUN
ecletica-1322	132	19	protein	protein	NOUN
ecletica-1322	132	20	were	be	AUX
ecletica-1322	132	21	identified	identify	VERB
ecletica-1322	132	22	.	.	PUNCT
ecletica-1322	133	1	the	the	DET
ecletica-1322	133	2	adme	adme	NOUN
ecletica-1322	133	3	features	feature	NOUN
ecletica-1322	133	4	showed	show	VERB
ecletica-1322	133	5	that	that	SCONJ
ecletica-1322	133	6	substituted	substitute	VERB
ecletica-1322	133	7	–	–	PUNCT
ecletica-1322	133	8	cooh	cooh	NOUN
ecletica-1322	133	9	and	and	CCONJ
ecletica-1322	133	10	–	–	PUNCT
ecletica-1322	133	11	no2	no2	NOUN
ecletica-1322	133	12	nitroimidazole	nitroimidazole	NOUN
ecletica-1322	133	13	derivatives	derivative	NOUN
ecletica-1322	133	14	has	have	VERB
ecletica-1322	133	15	the	the	DET
ecletica-1322	133	16	same	same	ADJ
ecletica-1322	133	17	binding	bind	VERB
ecletica-1322	133	18	energies	energy	NOUN
ecletica-1322	133	19	(	(	PUNCT
ecletica-1322	133	20	kj	kj	NOUN
ecletica-1322	133	21	mol–1	mol–1	PROPN
ecletica-1322	133	22	)	)	PUNCT
ecletica-1322	133	23	and	and	CCONJ
ecletica-1322	133	24	higher	high	ADJ
ecletica-1322	133	25	tendency	tendency	NOUN
ecletica-1322	133	26	to	to	PART
ecletica-1322	133	27	inhibit	inhibit	VERB
ecletica-1322	133	28	target	target	NOUN
ecletica-1322	133	29	nitroreductase	nitroreductase	NOUN
ecletica-1322	133	30	rdxa	rdxa	NOUN
ecletica-1322	133	31	protein	protein	NOUN
ecletica-1322	133	32	(	(	PUNCT
ecletica-1322	133	33	pdb	pdb	PROPN
ecletica-1322	133	34	i	i	PROPN
ecletica-1322	133	35	d	d	PROPN
ecletica-1322	133	36	:	:	PUNCT
ecletica-1322	133	37	3qdl	3qdl	NUM
ecletica-1322	133	38	)	)	PUNCT
ecletica-1322	133	39	than	than	ADP
ecletica-1322	133	40	the	the	DET
ecletica-1322	133	41	referenced	referenced	ADJ
ecletica-1322	133	42	drug	drug	NOUN
ecletica-1322	133	43	despite	despite	SCONJ
ecletica-1322	133	44	their	their	PRON
ecletica-1322	133	45	higher	high	ADJ
ecletica-1322	133	46	band	band	NOUN
ecletica-1322	133	47	gaps	gap	NOUN
ecletica-1322	133	48	.	.	PUNCT
ecletica-1322	134	1	the	the	DET
ecletica-1322	134	2	compounds	compound	NOUN
ecletica-1322	134	3	are	be	AUX
ecletica-1322	134	4	also	also	ADV
ecletica-1322	134	5	noninhibitors	noninhibitor	NOUN
ecletica-1322	134	6	and	and	CCONJ
ecletica-1322	134	7	nonsubstrates	nonsubstrate	NOUN
ecletica-1322	134	8	for	for	ADP
ecletica-1322	134	9	microsomal	microsomal	ADJ
ecletica-1322	134	10	enzymes	enzyme	NOUN
ecletica-1322	134	11	(	(	PUNCT
ecletica-1322	134	12	cyp450	cyp450	NOUN
ecletica-1322	134	13	2c9	2c9	NUM
ecletica-1322	134	14	,	,	PUNCT
ecletica-1322	134	15	cyp450	cyp450	NOUN
ecletica-1322	134	16	2d6	2d6	NUM
ecletica-1322	134	17	and	and	CCONJ
ecletica-1322	134	18	cyp450	cyp450	NOUN
ecletica-1322	134	19	2c19	2c19	NOUN
ecletica-1322	134	20	)	)	PUNCT
ecletica-1322	134	21	,	,	PUNCT
ecletica-1322	134	22	with	with	SCONJ
ecletica-1322	134	23	capacities	capacity	NOUN
ecletica-1322	134	24	to	to	PART
ecletica-1322	134	25	be	be	AUX
ecletica-1322	134	26	absorbed	absorb	VERB
ecletica-1322	134	27	in	in	ADP
ecletica-1322	134	28	the	the	DET
ecletica-1322	134	29	intestine	intestine	NOUN
ecletica-1322	134	30	and	and	CCONJ
ecletica-1322	134	31	ability	ability	NOUN
ecletica-1322	134	32	to	to	PART
ecletica-1322	134	33	cross	cross	VERB
ecletica-1322	134	34	the	the	DET
ecletica-1322	134	35	bbb	bbb	NOUN
ecletica-1322	134	36	comparable	comparable	ADJ
ecletica-1322	134	37	with	with	ADP
ecletica-1322	134	38	the	the	DET
ecletica-1322	134	39	standard	standard	NOUN
ecletica-1322	134	40	.	.	PUNCT
ecletica-1322	135	1	authors	author	NOUN
ecletica-1322	135	2	’	’	PART
ecletica-1322	135	3	contribution	contribution	NOUN
ecletica-1322	135	4	conceptualization	conceptualization	NOUN
ecletica-1322	135	5	:	:	PUNCT
ecletica-1322	135	6	adeoye	adeoye	PROPN
ecletica-1322	135	7	,	,	PUNCT
ecletica-1322	135	8	m.	m.	PROPN
ecletica-1322	135	9	d.	d.	PROPN
ecletica-1322	135	10	;	;	PUNCT
ecletica-1322	135	11	oyebamiji	oyebamiji	PROPN
ecletica-1322	135	12	,	,	PUNCT
ecletica-1322	135	13	a.	a.	PROPN
ecletica-1322	135	14	k.	k.	PROPN
ecletica-1322	135	15	data	data	PROPN
ecletica-1322	135	16	curation	curation	PROPN
ecletica-1322	135	17	:	:	PUNCT
ecletica-1322	135	18	adeoye	adeoye	PROPN
ecletica-1322	135	19	,	,	PUNCT
ecletica-1322	135	20	m.	m.	PROPN
ecletica-1322	135	21	d.	d.	PROPN
ecletica-1322	135	22	;	;	PUNCT
ecletica-1322	135	23	oyebamiji	oyebamiji	PROPN
ecletica-1322	135	24	,	,	PUNCT
ecletica-1322	135	25	a.	a.	NOUN
ecletica-1322	135	26	k.	k.	PROPN
ecletica-1322	136	1	formal	formal	ADJ
ecletica-1322	136	2	analysis	analysis	NOUN
ecletica-1322	136	3	:	:	PUNCT
ecletica-1322	136	4	adeoye	adeoye	PROPN
ecletica-1322	136	5	,	,	PUNCT
ecletica-1322	136	6	m.	m.	PROPN
ecletica-1322	136	7	d.	d.	PROPN
ecletica-1322	136	8	;	;	PUNCT
ecletica-1322	136	9	oyebamiji	oyebamiji	PROPN
ecletica-1322	136	10	,	,	PUNCT
ecletica-1322	136	11	a.	a.	PROPN
ecletica-1322	136	12	k.	k.	PROPN
ecletica-1322	136	13	funding	funding	PROPN
ecletica-1322	136	14	acquisition	acquisition	PROPN
ecletica-1322	136	15	:	:	PUNCT
ecletica-1322	136	16	ashiru	ashiru	PROPN
ecletica-1322	136	17	,	,	PUNCT
ecletica-1322	136	18	m.	m.	NOUN
ecletica-1322	136	19	j.	j.	PROPN
ecletica-1322	136	20	;	;	PUNCT
ecletica-1322	136	21	adigun	adigun	VERB
ecletica-1322	136	22	,	,	PUNCT
ecletica-1322	136	23	r.	r.	PROPN
ecletica-1322	136	24	a.	a.	PROPN
ecletica-1322	136	25	investigation	investigation	PROPN
ecletica-1322	136	26	:	:	PUNCT
ecletica-1322	137	1	adeoye	adeoye	PROPN
ecletica-1322	137	2	,	,	PUNCT
ecletica-1322	137	3	m.	m.	PROPN
ecletica-1322	137	4	d.	d.	PROPN
ecletica-1322	137	5	methodology	methodology	PROPN
ecletica-1322	137	6	:	:	PUNCT
ecletica-1322	137	7	adeoye	adeoye	PROPN
ecletica-1322	137	8	,	,	PUNCT
ecletica-1322	137	9	m.	m.	PROPN
ecletica-1322	137	10	d.	d.	PROPN
ecletica-1322	137	11	project	project	PROPN
ecletica-1322	137	12	administration	administration	PROPN
ecletica-1322	137	13	:	:	PUNCT
ecletica-1322	137	14	adeoye	adeoye	PROPN
ecletica-1322	137	15	,	,	PUNCT
ecletica-1322	137	16	m.	m.	PROPN
ecletica-1322	137	17	d.	d.	PROPN
ecletica-1322	137	18	resources	resource	NOUN
ecletica-1322	137	19	:	:	PUNCT
ecletica-1322	137	20	olalere	olalere	ADV
ecletica-1322	137	21	,	,	PUNCT
ecletica-1322	137	22	o.	o.	PROPN
ecletica-1322	137	23	h.	h.	PROPN
ecletica-1322	137	24	software	software	PROPN
ecletica-1322	137	25	:	:	PUNCT
ecletica-1322	138	1	semire	semire	PROPN
ecletica-1322	138	2	,	,	PUNCT
ecletica-1322	138	3	b.	b.	PROPN
ecletica-1322	138	4	supervision	supervision	PROPN
ecletica-1322	138	5	:	:	PUNCT
ecletica-1322	138	6	semire	semire	PROPN
ecletica-1322	138	7	,	,	PUNCT
ecletica-1322	138	8	b.	b.	PROPN
ecletica-1322	138	9	validation	validation	NOUN
ecletica-1322	138	10	:	:	PUNCT
ecletica-1322	138	11	oyebamiji	oyebamiji	NOUN
ecletica-1322	138	12	,	,	PUNCT
ecletica-1322	138	13	a.	a.	NOUN
ecletica-1322	138	14	k.	k.	PROPN
ecletica-1322	138	15	visualization	visualization	PROPN
ecletica-1322	138	16	:	:	PUNCT
ecletica-1322	138	17	adeoye	adeoye	PROPN
ecletica-1322	138	18	,	,	PUNCT
ecletica-1322	138	19	m.	m.	PROPN
ecletica-1322	138	20	d.	d.	PROPN
ecletica-1322	138	21	;	;	PUNCT
ecletica-1322	138	22	oyebamiji	oyebamiji	PROPN
ecletica-1322	138	23	,	,	PUNCT
ecletica-1322	138	24	a.	a.	PROPN
ecletica-1322	138	25	k.	k.	PROPN
ecletica-1322	138	26	writing	writing	PROPN
ecletica-1322	138	27	–	–	PUNCT
ecletica-1322	138	28	original	original	ADJ
ecletica-1322	138	29	draft	draft	NOUN
ecletica-1322	138	30	:	:	PUNCT
ecletica-1322	138	31	adeoye	adeoye	PROPN
ecletica-1322	138	32	,	,	PUNCT
ecletica-1322	138	33	m.	m.	PROPN
ecletica-1322	138	34	d.	d.	PROPN
ecletica-1322	138	35	writing	write	VERB
ecletica-1322	138	36	–	–	PUNCT
ecletica-1322	138	37	review	review	NOUN
ecletica-1322	138	38	&	&	CCONJ
ecletica-1322	138	39	editing	editing	NOUN
ecletica-1322	138	40	:	:	PUNCT
ecletica-1322	138	41	oyebamiji	oyebamiji	NOUN
ecletica-1322	138	42	,	,	PUNCT
ecletica-1322	138	43	a.	a.	PROPN
ecletica-1322	138	44	k.	k.	PROPN
ecletica-1322	138	45	data	data	PROPN
ecletica-1322	138	46	availability	availability	NOUN
ecletica-1322	138	47	statement	statement	NOUN
ecletica-1322	138	48	all	all	DET
ecletica-1322	138	49	data	datum	NOUN
ecletica-1322	138	50	sets	set	NOUN
ecletica-1322	138	51	were	be	AUX
ecletica-1322	138	52	generated	generate	VERB
ecletica-1322	138	53	or	or	CCONJ
ecletica-1322	138	54	analyzed	analyze	VERB
ecletica-1322	138	55	in	in	ADP
ecletica-1322	138	56	the	the	DET
ecletica-1322	138	57	current	current	ADJ
ecletica-1322	138	58	study	study	NOUN
ecletica-1322	138	59	.	.	PUNCT
ecletica-1322	139	1	funding	funding	NOUN
ecletica-1322	139	2	not	not	PART
ecletica-1322	139	3	applicable	applicable	ADJ
ecletica-1322	139	4	acknowledgments	acknowledgment	NOUN
ecletica-1322	139	5	we	we	PRON
ecletica-1322	139	6	are	be	AUX
ecletica-1322	139	7	grateful	grateful	ADJ
ecletica-1322	139	8	to	to	ADP
ecletica-1322	139	9	computational	computational	ADJ
ecletica-1322	139	10	chemistry	chemistry	NOUN
ecletica-1322	139	11	research	research	NOUN
ecletica-1322	139	12	laboratory	laboratory	NOUN
ecletica-1322	139	13	,	,	PUNCT
ecletica-1322	139	14	chemical	chemical	PROPN
ecletica-1322	139	15	sciences	sciences	PROPN
ecletica-1322	139	16	department	department	PROPN
ecletica-1322	139	17	,	,	PUNCT
ecletica-1322	139	18	fountain	fountain	NOUN
ecletica-1322	139	19	university	university	PROPN
ecletica-1322	139	20	and	and	CCONJ
ecletica-1322	139	21	mrs	mrs	PROPN
ecletica-1322	139	22	.	.	PROPN
ecletica-1322	139	23	e.	e.	PROPN
ecletica-1322	139	24	t.	t.	PROPN
ecletica-1322	139	25	oyebamiji	oyebamiji	PROPN
ecletica-1322	139	26	as	as	ADV
ecletica-1322	139	27	well	well	ADV
ecletica-1322	139	28	as	as	ADP
ecletica-1322	139	29	miss	miss	PROPN
ecletica-1322	139	30	priscilla	priscilla	PROPN
ecletica-1322	139	31	f.	f.	PROPN
ecletica-1322	139	32	oyebamiji	oyebamiji	PROPN
ecletica-1322	139	33	for	for	ADP
ecletica-1322	139	34	the	the	DET
ecletica-1322	139	35	assistance	assistance	NOUN
ecletica-1322	139	36	in	in	ADP
ecletica-1322	139	37	the	the	DET
ecletica-1322	139	38	course	course	NOUN
ecletica-1322	139	39	of	of	ADP
ecletica-1322	139	40	this	this	DET
ecletica-1322	139	41	study	study	NOUN
ecletica-1322	139	42	.	.	PUNCT
ecletica-1322	140	1	references	reference	NOUN
ecletica-1322	140	2	abdul	abdul	PROPN
ecletica-1322	140	3	-	-	PUNCT
ecletica-1322	140	4	hammed	ham	VERB
ecletica-1322	140	5	,	,	PUNCT
ecletica-1322	140	6	m.	m.	NOUN
ecletica-1322	140	7	;	;	PUNCT
ecletica-1322	140	8	semire	semire	NOUN
ecletica-1322	140	9	,	,	PUNCT
ecletica-1322	140	10	b.	b.	PROPN
ecletica-1322	140	11	;	;	PUNCT
ecletica-1322	140	12	adegboyega	adegboyega	PROPN
ecletica-1322	140	13	,	,	PUNCT
ecletica-1322	140	14	s.	s.	PROPN
ecletica-1322	140	15	a.	a.	PROPN
ecletica-1322	140	16	;	;	PUNCT
ecletica-1322	140	17	oyebamiji	oyebamiji	NOUN
ecletica-1322	140	18	,	,	PUNCT
ecletica-1322	140	19	a.	a.	PROPN
ecletica-1322	140	20	k.	k.	PROPN
ecletica-1322	140	21	;	;	PUNCT
ecletica-1322	140	22	olowolafe	olowolafe	NOUN
ecletica-1322	140	23	,	,	PUNCT
ecletica-1322	140	24	t.	t.	NOUN
ecletica-1322	140	25	a.	a.	NOUN
ecletica-1322	140	26	inhibition	inhibition	NOUN
ecletica-1322	140	27	of	of	ADP
ecletica-1322	140	28	cyclooxygenase-2	cyclooxygenase-2	NUM
ecletica-1322	140	29	and	and	CCONJ
ecletica-1322	140	30	thymidylate	thymidylate	VERB
ecletica-1322	140	31	synthase	synthase	NOUN
ecletica-1322	140	32	by	by	ADP
ecletica-1322	140	33	dietary	dietary	ADJ
ecletica-1322	140	34	sphingomyelins	sphingomyelin	NOUN
ecletica-1322	140	35	:	:	PUNCT
ecletica-1322	140	36	insights	insight	NOUN
ecletica-1322	140	37	from	from	ADP
ecletica-1322	140	38	dft	dft	PROPN
ecletica-1322	140	39	and	and	CCONJ
ecletica-1322	140	40	molecular	molecular	ADJ
ecletica-1322	140	41	docking	docking	NOUN
ecletica-1322	140	42	studies	study	NOUN
ecletica-1322	140	43	.	.	PUNCT
ecletica-1322	141	1	phys	phy	NOUN
ecletica-1322	141	2	.	.	PUNCT
ecletica-1322	142	1	chem	chem	PROPN
ecletica-1322	142	2	.	.	PUNCT
ecletica-1322	143	1	res	re	NOUN
ecletica-1322	143	2	.	.	PUNCT
ecletica-1322	144	1	2020	2020	NUM
ecletica-1322	144	2	,	,	PUNCT
ecletica-1322	144	3	8	8	NUM
ecletica-1322	144	4	(	(	PUNCT
ecletica-1322	144	5	2	2	NUM
ecletica-1322	144	6	)	)	PUNCT
ecletica-1322	144	7	,	,	PUNCT
ecletica-1322	145	1	297–311	297–311	NUM
ecletica-1322	145	2	.	.	PUNCT
ecletica-1322	146	1	https://doi.org/10.22036/pcr.2020.214026.1717	https://doi.org/10.22036/pcr.2020.214026.1717	ADJ
ecletica-1322	146	2	adegoke	adegoke	NOUN
ecletica-1322	146	3	,	,	PUNCT
ecletica-1322	146	4	r.	r.	PROPN
ecletica-1322	146	5	o.	o.	PROPN
ecletica-1322	146	6	;	;	PUNCT
ecletica-1322	146	7	oyebamiji	oyebamiji	PROPN
ecletica-1322	146	8	,	,	PUNCT
ecletica-1322	146	9	a.	a.	PROPN
ecletica-1322	146	10	k.	k.	PROPN
ecletica-1322	146	11	;	;	PUNCT
ecletica-1322	146	12	semire	semire	PROPN
ecletica-1322	146	13	,	,	PUNCT
ecletica-1322	146	14	b.	b.	PROPN
ecletica-1322	146	15	dataset	dataset	PROPN
ecletica-1322	146	16	on	on	ADP
ecletica-1322	146	17	the	the	DET
ecletica-1322	146	18	dft	dft	NOUN
ecletica-1322	146	19	-	-	PUNCT
ecletica-1322	146	20	qsar	qsar	NOUN
ecletica-1322	146	21	,	,	PUNCT
ecletica-1322	146	22	and	and	CCONJ
ecletica-1322	146	23	docking	dock	VERB
ecletica-1322	146	24	approaches	approach	NOUN
ecletica-1322	146	25	for	for	ADP
ecletica-1322	146	26	anticancer	anticancer	NOUN
ecletica-1322	146	27	activities	activity	NOUN
ecletica-1322	146	28	of	of	ADP
ecletica-1322	146	29	1	1	NUM
ecletica-1322	146	30	,	,	PUNCT
ecletica-1322	146	31	2	2	NUM
ecletica-1322	146	32	,	,	PUNCT
ecletica-1322	146	33	3	3	NUM
ecletica-1322	146	34	-	-	PUNCT
ecletica-1322	146	35	triazole	triazole	ADJ
ecletica-1322	146	36	-	-	PUNCT
ecletica-1322	146	37	pyrimidine	pyrimidine	NOUN
ecletica-1322	146	38	derivatives	derivative	NOUN
ecletica-1322	146	39	against	against	ADP
ecletica-1322	146	40	human	human	ADJ
ecletica-1322	146	41	https://revista.iq.unesp.br/index.php/ecletica	https://revista.iq.unesp.br/index.php/ecletica	NOUN
ecletica-1322	146	42	https://doi.org/10.26850/1678-4618eqj.v47.4.2022.p27-36	https://doi.org/10.26850/1678-4618eqj.v47.4.2022.p27-36	NOUN
ecletica-1322	146	43	https://doi.org/10.22036/pcr.2020.214026.1717	https://doi.org/10.22036/pcr.2020.214026.1717	PRON
ecletica-1322	146	44	https://doi.org/10.22036/pcr.2020.214026.1717	https://doi.org/10.22036/pcr.2020.214026.1717	ADP
ecletica-1322	146	45	https://doi.org/10.22036/pcr.2020.214026.1717	https://doi.org/10.22036/pcr.2020.214026.1717	ADJ
ecletica-1322	146	46	https://doi.org/10.22036/pcr.2020.214026.1717	https://doi.org/10.22036/pcr.2020.214026.1717	ADJ
ecletica-1322	146	47	https://doi.org/10.22036/pcr.2020.214026.1717	https://doi.org/10.22036/pcr.2020.214026.1717	ADJ
ecletica-1322	146	48	https://doi.org/10.22036/pcr.2020.214026.1717	https://doi.org/10.22036/pcr.2020.214026.1717	X
ecletica-1322	146	49	https://doi.org/10.1016/j.dib.2020.105963	https://doi.org/10.1016/j.dib.2020.105963	PROPN
ecletica-1322	146	50	https://doi.org/10.1016/j.dib.2020.105963	https://doi.org/10.1016/j.dib.2020.105963	PROPN
ecletica-1322	146	51	https://doi.org/10.1016/j.dib.2020.105963	https://doi.org/10.1016/j.dib.2020.105963	PROPN
ecletica-1322	146	52	original	original	ADJ
ecletica-1322	146	53	article	article	NOUN
ecletica-1322	146	54	revista.iq.unesp.br	revista.iq.unesp.br	PROPN
ecletica-1322	146	55	35	35	NUM
ecletica-1322	146	56	eclética	eclética	PROPN
ecletica-1322	146	57	química	química	PROPN
ecletica-1322	146	58	journal	journal	PROPN
ecletica-1322	146	59	,	,	PUNCT
ecletica-1322	146	60	vol	vol	NOUN
ecletica-1322	146	61	.	.	PROPN
ecletica-1322	147	1	47	47	NUM
ecletica-1322	147	2	,	,	PUNCT
ecletica-1322	147	3	n.	n.	NOUN
ecletica-1322	147	4	4	4	NUM
ecletica-1322	147	5	,	,	PUNCT
ecletica-1322	147	6	2022	2022	NUM
ecletica-1322	147	7	,	,	PUNCT
ecletica-1322	147	8	27	27	NUM
ecletica-1322	147	9	-	-	SYM
ecletica-1322	147	10	36	36	NUM
ecletica-1322	147	11	issn	issn	NOUN
ecletica-1322	147	12	:	:	PUNCT
ecletica-1322	147	13	1678	1678	NUM
ecletica-1322	147	14	-	-	SYM
ecletica-1322	147	15	4618	4618	NUM
ecletica-1322	147	16	doi	doi	NOUN
ecletica-1322	147	17	:	:	PUNCT
ecletica-1322	147	18	10.26850/1678	10.26850/1678	NUM
ecletica-1322	147	19	-	-	SYM
ecletica-1322	147	20	4618eqj.v47.4.2022.p27	4618eqj.v47.4.2022.p27	NUM
ecletica-1322	147	21	-	-	PUNCT
ecletica-1322	147	22	36	36	NUM
ecletica-1322	147	23	esophageal	esophageal	ADJ
ecletica-1322	147	24	carcinoma	carcinoma	NOUN
ecletica-1322	147	25	(	(	PUNCT
ecletica-1322	147	26	ec-109	ec-109	PROPN
ecletica-1322	147	27	)	)	PUNCT
ecletica-1322	147	28	.	.	PUNCT
ecletica-1322	148	1	data	data	PROPN
ecletica-1322	148	2	br	br	PROPN
ecletica-1322	148	3	.	.	PROPN
ecletica-1322	148	4	2020	2020	NUM
ecletica-1322	148	5	,	,	PUNCT
ecletica-1322	148	6	31	31	NUM
ecletica-1322	148	7	,	,	PUNCT
ecletica-1322	148	8	105963	105963	NUM
ecletica-1322	148	9	.	.	PUNCT
ecletica-1322	149	1	https://doi.org/10.1016/j.dib.2020.105963	https://doi.org/10.1016/j.dib.2020.105963	PROPN
ecletica-1322	149	2	adejoro	adejoro	PROPN
ecletica-1322	149	3	,	,	PUNCT
ecletica-1322	149	4	i.	i.	PROPN
ecletica-1322	149	5	a.	a.	PROPN
ecletica-1322	149	6	;	;	PUNCT
ecletica-1322	149	7	waheed	waheed	PROPN
ecletica-1322	149	8	,	,	PUNCT
ecletica-1322	149	9	s.	s.	PROPN
ecletica-1322	149	10	o.	o.	PROPN
ecletica-1322	149	11	;	;	PUNCT
ecletica-1322	149	12	adeboye	adeboye	NOUN
ecletica-1322	149	13	,	,	PUNCT
ecletica-1322	149	14	o.	o.	NOUN
ecletica-1322	149	15	o.	o.	PROPN
ecletica-1322	149	16	molecular	molecular	ADJ
ecletica-1322	149	17	docking	docking	NOUN
ecletica-1322	149	18	studies	study	NOUN
ecletica-1322	149	19	of	of	ADP
ecletica-1322	149	20	lonchocarpus	lonchocarpus	PROPN
ecletica-1322	149	21	cyanescens	cyanescen	NOUN
ecletica-1322	149	22	triterpenoids	triterpenoid	NOUN
ecletica-1322	149	23	as	as	ADP
ecletica-1322	149	24	inhibitors	inhibitor	NOUN
ecletica-1322	149	25	for	for	ADP
ecletica-1322	149	26	malaria	malaria	NOUN
ecletica-1322	149	27	.	.	PUNCT
ecletica-1322	150	1	j.	j.	PROPN
ecletica-1322	150	2	phys	phys	PROPN
ecletica-1322	150	3	.	.	PUNCT
ecletica-1322	151	1	chem	chem	PROPN
ecletica-1322	151	2	.	.	PUNCT
ecletica-1322	152	1	biophys	biophy	NOUN
ecletica-1322	152	2	.	.	PUNCT
ecletica-1322	153	1	2016	2016	NUM
ecletica-1322	153	2	,	,	PUNCT
ecletica-1322	153	3	6	6	NUM
ecletica-1322	153	4	(	(	PUNCT
ecletica-1322	153	5	2	2	NUM
ecletica-1322	153	6	)	)	PUNCT
ecletica-1322	153	7	,	,	PUNCT
ecletica-1322	153	8	1000213	1000213	NUM
ecletica-1322	153	9	.	.	PUNCT
ecletica-1322	154	1	https://doi.org/10.4172/2161-0398.1000213	https://doi.org/10.4172/2161-0398.1000213	PROPN
ecletica-1322	154	2	adeoye	adeoye	PROPN
ecletica-1322	154	3	,	,	PUNCT
ecletica-1322	154	4	m.	m.	PROPN
ecletica-1322	154	5	d.	d.	PROPN
ecletica-1322	154	6	;	;	PUNCT
ecletica-1322	154	7	obi	obi	PROPN
ecletica-1322	154	8	-	-	PUNCT
ecletica-1322	154	9	egbedi	egbedi	PROPN
ecletica-1322	154	10	,	,	PUNCT
ecletica-1322	154	11	n.	n.	PROPN
ecletica-1322	154	12	o.	o.	PROPN
ecletica-1322	154	13	;	;	PUNCT
ecletica-1322	154	14	iweibo	iweibo	PROPN
ecletica-1322	154	15	,	,	PUNCT
ecletica-1322	154	16	i.	i.	PROPN
ecletica-1322	154	17	solvent	solvent	PROPN
ecletica-1322	154	18	effect	effect	NOUN
ecletica-1322	154	19	and	and	CCONJ
ecletica-1322	154	20	photo	photo	NOUN
ecletica-1322	154	21	-	-	PUNCT
ecletica-1322	154	22	physical	physical	ADJ
ecletica-1322	154	23	properties	property	NOUN
ecletica-1322	154	24	of	of	ADP
ecletica-1322	154	25	2	2	NUM
ecletica-1322	154	26	,	,	PUNCT
ecletica-1322	154	27	3diphenylcyclopropenone	3diphenylcyclopropenone	NUM
ecletica-1322	154	28	.	.	PUNCT
ecletica-1322	154	29	arabian	arabian	ADJ
ecletica-1322	154	30	journal	journal	PROPN
ecletica-1322	154	31	of	of	ADP
ecletica-1322	154	32	chemistry	chemistry	PROPN
ecletica-1322	154	33	2017	2017	NUM
ecletica-1322	154	34	,	,	PUNCT
ecletica-1322	154	35	10	10	NUM
ecletica-1322	154	36	(	(	PUNCT
ecletica-1322	154	37	suppl	suppl	ADJ
ecletica-1322	154	38	1	1	NUM
ecletica-1322	154	39	)	)	PUNCT
ecletica-1322	154	40	,	,	PUNCT
ecletica-1322	154	41	s134	s134	PROPN
ecletica-1322	154	42	–	–	PUNCT
ecletica-1322	154	43	s140	s140	PROPN
ecletica-1322	154	44	.	.	PROPN
ecletica-1322	155	1	https://doi.org/10.1016/j.arabjc.2012.06.019	https://doi.org/10.1016/j.arabjc.2012.06.019	PROPN
ecletica-1322	155	2	adeoye	adeoye	PROPN
ecletica-1322	155	3	,	,	PUNCT
ecletica-1322	155	4	m.	m.	PROPN
ecletica-1322	155	5	d.	d.	PROPN
ecletica-1322	155	6	;	;	PUNCT
ecletica-1322	155	7	abdulsalami	abdulsalami	PROPN
ecletica-1322	155	8	,	,	PUNCT
ecletica-1322	155	9	i.	i.	PROPN
ecletica-1322	155	10	o.	o.	PROPN
ecletica-1322	155	11	;	;	PUNCT
ecletica-1322	155	12	oyeleke	oyeleke	PROPN
ecletica-1322	155	13	,	,	PUNCT
ecletica-1322	155	14	g.	g.	PROPN
ecletica-1322	155	15	o.	o.	PROPN
ecletica-1322	155	16	;	;	PUNCT
ecletica-1322	155	17	alabi	alabi	PROPN
ecletica-1322	155	18	,	,	PUNCT
ecletica-1322	155	19	k.	k.	PROPN
ecletica-1322	155	20	a.	a.	PROPN
ecletica-1322	155	21	theoretical	theoretical	PROPN
ecletica-1322	155	22	studies	study	NOUN
ecletica-1322	155	23	of	of	ADP
ecletica-1322	155	24	solvent	solvent	ADJ
ecletica-1322	155	25	effects	effect	NOUN
ecletica-1322	155	26	on	on	ADP
ecletica-1322	155	27	the	the	DET
ecletica-1322	155	28	electronic	electronic	ADJ
ecletica-1322	155	29	properties	property	NOUN
ecletica-1322	155	30	of	of	ADP
ecletica-1322	155	31	1	1	NUM
ecletica-1322	155	32	,	,	PUNCT
ecletica-1322	155	33	3	3	NUM
ecletica-1322	155	34	-	-	PUNCT
ecletica-1322	155	35	bis	bis	NOUN
ecletica-1322	156	1	[	[	X
ecletica-1322	156	2	(	(	PUNCT
ecletica-1322	156	3	furan-2	furan-2	NOUN
ecletica-1322	156	4	-	-	PUNCT
ecletica-1322	156	5	yl	yl	NOUN
ecletica-1322	156	6	)	)	PUNCT
ecletica-1322	156	7	methylene	methylene	NOUN
ecletica-1322	156	8	]	]	PUNCT
ecletica-1322	156	9	urea	urea	NOUN
ecletica-1322	156	10	and	and	CCONJ
ecletica-1322	156	11	thiourea	thiourea	NOUN
ecletica-1322	156	12	.	.	PUNCT
ecletica-1322	157	1	j.	j.	PROPN
ecletica-1322	157	2	phys	phys	PROPN
ecletica-1322	157	3	.	.	PUNCT
ecletica-1322	158	1	theor	theor	PROPN
ecletica-1322	158	2	.	.	PUNCT
ecletica-1322	158	3	chem	chem	PROPN
ecletica-1322	158	4	.	.	PUNCT
ecletica-1322	159	1	iau	iau	PROPN
ecletica-1322	159	2	,	,	PUNCT
ecletica-1322	159	3	iran	iran	PROPN
ecletica-1322	159	4	.	.	PUNCT
ecletica-1322	160	1	2019	2019	NUM
ecletica-1322	160	2	,	,	PUNCT
ecletica-1322	160	3	15	15	NUM
ecletica-1322	160	4	(	(	PUNCT
ecletica-1322	160	5	3–4	3–4	NUM
ecletica-1322	160	6	)	)	PUNCT
ecletica-1322	160	7	,	,	PUNCT
ecletica-1322	160	8	115–125	115–125	NUM
ecletica-1322	160	9	.	.	PUNCT
ecletica-1322	160	10	adeoye	adeoye	PROPN
ecletica-1322	160	11	,	,	PUNCT
ecletica-1322	160	12	m.	m.	PROPN
ecletica-1322	160	13	d.	d.	PROPN
ecletica-1322	160	14	;	;	PUNCT
ecletica-1322	160	15	olarinoye	olarinoye	PROPN
ecletica-1322	160	16	,	,	PUNCT
ecletica-1322	160	17	e.	e.	PROPN
ecletica-1322	160	18	f.	f.	PROPN
ecletica-1322	160	19	;	;	PUNCT
ecletica-1322	160	20	oyebamiji	oyebamiji	PROPN
ecletica-1322	160	21	,	,	PUNCT
ecletica-1322	160	22	a.	a.	PROPN
ecletica-1322	160	23	k.	k.	PROPN
ecletica-1322	160	24	;	;	PUNCT
ecletica-1322	160	25	latona	latona	PROPN
ecletica-1322	160	26	,	,	PUNCT
ecletica-1322	160	27	d.	d.	PROPN
ecletica-1322	160	28	f.	f.	PROPN
ecletica-1322	160	29	theoretical	theoretical	ADJ
ecletica-1322	160	30	evaluation	evaluation	NOUN
ecletica-1322	160	31	of	of	ADP
ecletica-1322	160	32	potential	potential	ADJ
ecletica-1322	160	33	anti	anti	ADJ
ecletica-1322	160	34	-	-	ADJ
ecletica-1322	160	35	alanine	alanine	ADJ
ecletica-1322	160	36	dehydrogenase	dehydrogenase	NOUN
ecletica-1322	160	37	activities	activity	NOUN
ecletica-1322	160	38	of	of	ADP
ecletica-1322	160	39	acetamide	acetamide	NOUN
ecletica-1322	160	40	derivatives	derivative	NOUN
ecletica-1322	160	41	.	.	PUNCT
ecletica-1322	161	1	biointerface	biointerface	NOUN
ecletica-1322	161	2	res	re	NOUN
ecletica-1322	161	3	.	.	PUNCT
ecletica-1322	162	1	appl	appl	PROPN
ecletica-1322	162	2	.	.	PUNCT
ecletica-1322	163	1	chem	chem	PROPN
ecletica-1322	163	2	.	.	PUNCT
ecletica-1322	164	1	2022	2022	NUM
ecletica-1322	164	2	,	,	PUNCT
ecletica-1322	164	3	12	12	NUM
ecletica-1322	164	4	(	(	PUNCT
ecletica-1322	164	5	6	6	NUM
ecletica-1322	164	6	)	)	PUNCT
ecletica-1322	164	7	,	,	PUNCT
ecletica-1322	164	8	7469–7477	7469–7477	NUM
ecletica-1322	164	9	https://doi.org/10.33263/briac126.74697477	https://doi.org/10.33263/briac126.74697477	NUM
ecletica-1322	164	10	akintelu	akintelu	ADV
ecletica-1322	164	11	,	,	PUNCT
ecletica-1322	164	12	s.	s.	PROPN
ecletica-1322	164	13	a.	a.	PROPN
ecletica-1322	164	14	;	;	PUNCT
ecletica-1322	164	15	folorunso	folorunso	NOUN
ecletica-1322	164	16	,	,	PUNCT
ecletica-1322	164	17	a.	a.	NOUN
ecletica-1322	164	18	s.	s.	PROPN
ecletica-1322	164	19	;	;	PUNCT
ecletica-1322	164	20	oyebamiji	oyebamiji	PROPN
ecletica-1322	164	21	,	,	PUNCT
ecletica-1322	164	22	a.	a.	NOUN
ecletica-1322	164	23	k.	k.	PROPN
ecletica-1322	164	24	phytochemical	phytochemical	ADJ
ecletica-1322	164	25	and	and	CCONJ
ecletica-1322	164	26	antibacterial	antibacterial	ADJ
ecletica-1322	164	27	investigation	investigation	NOUN
ecletica-1322	164	28	of	of	ADP
ecletica-1322	164	29	moringa	moringa	PROPN
ecletica-1322	164	30	oleifera	oleifera	NOUN
ecletica-1322	164	31	seed	seed	NOUN
ecletica-1322	164	32	:	:	PUNCT
ecletica-1322	164	33	experimental	experimental	ADJ
ecletica-1322	164	34	and	and	CCONJ
ecletica-1322	164	35	computational	computational	ADJ
ecletica-1322	164	36	approaches	approach	NOUN
ecletica-1322	164	37	.	.	PUNCT
ecletica-1322	165	1	eclet	eclet	NOUN
ecletica-1322	165	2	.	.	PUNCT
ecletica-1322	166	1	quim	quim	PROPN
ecletica-1322	166	2	.	.	PUNCT
ecletica-1322	167	1	j.	j.	PROPN
ecletica-1322	167	2	2021	2021	NUM
ecletica-1322	167	3	,	,	PUNCT
ecletica-1322	167	4	46	46	NUM
ecletica-1322	167	5	(	(	PUNCT
ecletica-1322	167	6	2	2	NUM
ecletica-1322	167	7	)	)	PUNCT
ecletica-1322	167	8	,	,	PUNCT
ecletica-1322	167	9	17–25	17–25	NUM
ecletica-1322	167	10	.	.	NOUN
ecletica-1322	167	11	https://doi.org/10.26850/1678-4618eqj.v46.2.2021.p17-25	https://doi.org/10.26850/1678-4618eqj.v46.2.2021.p17-25	PROPN
ecletica-1322	167	12	alawadi	alawadi	PROPN
ecletica-1322	167	13	,	,	PUNCT
ecletica-1322	167	14	d.	d.	PROPN
ecletica-1322	167	15	y.	y.	PROPN
ecletica-1322	167	16	;	;	PUNCT
ecletica-1322	167	17	saadeh	saadeh	PROPN
ecletica-1322	167	18	,	,	PUNCT
ecletica-1322	167	19	h.	h.	PROPN
ecletica-1322	167	20	a.	a.	PROPN
ecletica-1322	167	21	;	;	PUNCT
ecletica-1322	167	22	kaur	kaur	PROPN
ecletica-1322	167	23	,	,	PUNCT
ecletica-1322	167	24	h.	h.	PROPN
ecletica-1322	167	25	;	;	PUNCT
ecletica-1322	167	26	goyal	goyal	PROPN
ecletica-1322	167	27	,	,	PUNCT
ecletica-1322	167	28	k.	k.	PROPN
ecletica-1322	167	29	;	;	PUNCT
ecletica-1322	167	30	sehgal	sehgal	PROPN
ecletica-1322	167	31	,	,	PUNCT
ecletica-1322	167	32	r.	r.	PROPN
ecletica-1322	167	33	;	;	PUNCT
ecletica-1322	167	34	hadda	hadda	NOUN
ecletica-1322	167	35	,	,	PUNCT
ecletica-1322	167	36	t.	t.	PROPN
ecletica-1322	167	37	b.	b.	PROPN
ecletica-1322	167	38	;	;	PUNCT
ecletica-1322	167	39	elsawy	elsawy	PROPN
ecletica-1322	167	40	,	,	PUNCT
ecletica-1322	167	41	n.	n.	NOUN
ecletica-1322	167	42	a.	a.	PROPN
ecletica-1322	167	43	;	;	PUNCT
ecletica-1322	168	1	mubarak	mubarak	PROPN
ecletica-1322	168	2	,	,	PUNCT
ecletica-1322	168	3	m.	m.	NOUN
ecletica-1322	168	4	s.	s.	PROPN
ecletica-1322	168	5	metronidazole	metronidazole	PROPN
ecletica-1322	168	6	derivatives	derivative	NOUN
ecletica-1322	168	7	as	as	ADP
ecletica-1322	168	8	a	a	DET
ecletica-1322	168	9	new	new	ADJ
ecletica-1322	168	10	class	class	NOUN
ecletica-1322	168	11	of	of	ADP
ecletica-1322	168	12	antiparasitic	antiparasitic	ADJ
ecletica-1322	168	13	agents	agent	NOUN
ecletica-1322	168	14	:	:	PUNCT
ecletica-1322	168	15	synthesis	synthesis	NOUN
ecletica-1322	168	16	,	,	PUNCT
ecletica-1322	168	17	prediction	prediction	NOUN
ecletica-1322	168	18	of	of	ADP
ecletica-1322	168	19	biological	biological	ADJ
ecletica-1322	168	20	activity	activity	NOUN
ecletica-1322	168	21	,	,	PUNCT
ecletica-1322	168	22	and	and	CCONJ
ecletica-1322	168	23	molecular	molecular	ADJ
ecletica-1322	168	24	properties	property	NOUN
ecletica-1322	168	25	.	.	PUNCT
ecletica-1322	169	1	med	med	PROPN
ecletica-1322	169	2	.	.	PROPN
ecletica-1322	169	3	chem	chem	PROPN
ecletica-1322	169	4	.	.	PUNCT
ecletica-1322	170	1	res	re	NOUN
ecletica-1322	170	2	.	.	PROPN
ecletica-1322	170	3	2015	2015	NUM
ecletica-1322	170	4	,	,	PUNCT
ecletica-1322	170	5	24	24	NUM
ecletica-1322	170	6	(	(	PUNCT
ecletica-1322	170	7	9	9	NUM
ecletica-1322	170	8	)	)	PUNCT
ecletica-1322	170	9	,	,	PUNCT
ecletica-1322	170	10	1196	1196	NUM
ecletica-1322	170	11	–	–	PUNCT
ecletica-1322	170	12	1209	1209	NUM
ecletica-1322	170	13	.	.	PUNCT
ecletica-1322	171	1	https://doi.org/10.1007/s00044-014-1197-4	https://doi.org/10.1007/s00044-014-1197-4	PROPN
ecletica-1322	171	2	balani	balani	PROPN
ecletica-1322	171	3	,	,	PUNCT
ecletica-1322	171	4	s.	s.	PROPN
ecletica-1322	171	5	;	;	PUNCT
ecletica-1322	171	6	miwa	miwa	PROPN
ecletica-1322	171	7	,	,	PUNCT
ecletica-1322	171	8	g.	g.	PROPN
ecletica-1322	171	9	t.	t.	PROPN
ecletica-1322	171	10	;	;	PUNCT
ecletica-1322	171	11	gan	gan	PROPN
ecletica-1322	171	12	,	,	PUNCT
ecletica-1322	171	13	l.-s	l.-s	PROPN
ecletica-1322	171	14	.	.	PUNCT
ecletica-1322	171	15	;	;	PUNCT
ecletica-1322	171	16	wu	wu	PROPN
ecletica-1322	171	17	,	,	PUNCT
ecletica-1322	171	18	j.-t	j.-t	PROPN
ecletica-1322	171	19	.	.	PUNCT
ecletica-1322	171	20	;	;	PUNCT
ecletica-1322	171	21	lee	lee	PROPN
ecletica-1322	171	22	,	,	PUNCT
ecletica-1322	171	23	f.	f.	PROPN
ecletica-1322	171	24	w.	w.	PROPN
ecletica-1322	171	25	strategy	strategy	NOUN
ecletica-1322	171	26	of	of	ADP
ecletica-1322	171	27	utilizing	utilize	VERB
ecletica-1322	171	28	in	in	ADP
ecletica-1322	171	29	-	-	PUNCT
ecletica-1322	171	30	vitro	vitro	X
ecletica-1322	171	31	and	and	CCONJ
ecletica-1322	171	32	in	in	ADP
ecletica-1322	171	33	-	-	PUNCT
ecletica-1322	171	34	vivo	vivo	NOUN
ecletica-1322	171	35	adme	adme	NOUN
ecletica-1322	171	36	tools	tool	NOUN
ecletica-1322	171	37	for	for	ADP
ecletica-1322	171	38	lead	lead	ADJ
ecletica-1322	171	39	optimization	optimization	NOUN
ecletica-1322	171	40	and	and	CCONJ
ecletica-1322	171	41	drug	drug	NOUN
ecletica-1322	171	42	candidate	candidate	NOUN
ecletica-1322	171	43	selection	selection	NOUN
ecletica-1322	171	44	.	.	PUNCT
ecletica-1322	172	1	curr	curr	PROPN
ecletica-1322	172	2	.	.	PUNCT
ecletica-1322	172	3	top	top	PROPN
ecletica-1322	172	4	.	.	PUNCT
ecletica-1322	173	1	med	med	PROPN
ecletica-1322	173	2	.	.	PROPN
ecletica-1322	173	3	chem	chem	PROPN
ecletica-1322	173	4	.	.	PUNCT
ecletica-1322	174	1	2005	2005	NUM
ecletica-1322	174	2	,	,	PUNCT
ecletica-1322	174	3	5	5	NUM
ecletica-1322	174	4	(	(	PUNCT
ecletica-1322	174	5	11	11	NUM
ecletica-1322	174	6	)	)	PUNCT
ecletica-1322	174	7	,	,	PUNCT
ecletica-1322	174	8	1033–1038	1033–1038	NUM
ecletica-1322	174	9	.	.	PUNCT
ecletica-1322	174	10	https://doi.org/10.2174/156802605774297038	https://doi.org/10.2174/156802605774297038	VERB
ecletica-1322	174	11	bürgers	bürgers	PROPN
ecletica-1322	174	12	,	,	PUNCT
ecletica-1322	174	13	r.	r.	PROPN
ecletica-1322	174	14	;	;	PUNCT
ecletica-1322	174	15	schneider	schneider	NOUN
ecletica-1322	174	16	-	-	PUNCT
ecletica-1322	174	17	brachert	brachert	PROPN
ecletica-1322	174	18	,	,	PUNCT
ecletica-1322	174	19	w.	w.	PROPN
ecletica-1322	174	20	;	;	PUNCT
ecletica-1322	174	21	reischl	reischl	PROPN
ecletica-1322	174	22	,	,	PUNCT
ecletica-1322	174	23	u.	u.	PROPN
ecletica-1322	174	24	;	;	PUNCT
ecletica-1322	174	25	behr	behr	NOUN
ecletica-1322	174	26	,	,	PUNCT
ecletica-1322	174	27	a.	a.	NOUN
ecletica-1322	174	28	;	;	PUNCT
ecletica-1322	174	29	hiller	hiller	NOUN
ecletica-1322	174	30	,	,	PUNCT
ecletica-1322	174	31	k.-a	k.-a	PROPN
ecletica-1322	174	32	.	.	PUNCT
ecletica-1322	175	1	;	;	PUNCT
ecletica-1322	175	2	lehn	lehn	NOUN
ecletica-1322	175	3	,	,	PUNCT
ecletica-1322	175	4	n.	n.	PROPN
ecletica-1322	175	5	;	;	PUNCT
ecletica-1322	175	6	schmalz	schmalz	PROPN
ecletica-1322	175	7	,	,	PUNCT
ecletica-1322	175	8	g.	g.	PROPN
ecletica-1322	175	9	;	;	PUNCT
ecletica-1322	175	10	ruhl	ruhl	PROPN
ecletica-1322	175	11	,	,	PUNCT
ecletica-1322	175	12	s.	s.	PROPN
ecletica-1322	175	13	helicobacter	helicobacter	NOUN
ecletica-1322	175	14	pylori	pylori	NOUN
ecletica-1322	175	15	in	in	ADP
ecletica-1322	175	16	human	human	ADJ
ecletica-1322	175	17	oral	oral	ADJ
ecletica-1322	175	18	cavity	cavity	NOUN
ecletica-1322	175	19	and	and	CCONJ
ecletica-1322	175	20	stomach	stomach	NOUN
ecletica-1322	175	21	.	.	PUNCT
ecletica-1322	176	1	eur	eur	PROPN
ecletica-1322	176	2	.	.	PUNCT
ecletica-1322	177	1	j.	j.	PROPN
ecletica-1322	177	2	oral	oral	PROPN
ecletica-1322	177	3	.	.	PUNCT
ecletica-1322	178	1	sci	sci	PROPN
ecletica-1322	178	2	.	.	PROPN
ecletica-1322	178	3	2008	2008	NUM
ecletica-1322	178	4	,	,	PUNCT
ecletica-1322	178	5	116	116	NUM
ecletica-1322	178	6	(	(	PUNCT
ecletica-1322	178	7	4	4	NUM
ecletica-1322	178	8	)	)	PUNCT
ecletica-1322	178	9	,	,	PUNCT
ecletica-1322	178	10	297–304	297–304	NUM
ecletica-1322	178	11	.	.	PUNCT
ecletica-1322	179	1	https://doi.org/10.1111/j.16000722.2008.00543.x	https://doi.org/10.1111/j.16000722.2008.00543.x	X
ecletica-1322	179	2	choi	choi	PROPN
ecletica-1322	179	3	,	,	PUNCT
ecletica-1322	179	4	h.	h.	PROPN
ecletica-1322	179	5	;	;	PUNCT
ecletica-1322	179	6	kang	kang	PROPN
ecletica-1322	179	7	,	,	PUNCT
ecletica-1322	179	8	h.	h.	PROPN
ecletica-1322	179	9	;	;	PUNCT
ecletica-1322	179	10	park	park	PROPN
ecletica-1322	179	11	,	,	PUNCT
ecletica-1322	179	12	h.	h.	PROPN
ecletica-1322	179	13	new	new	ADJ
ecletica-1322	179	14	solvation	solvation	NOUN
ecletica-1322	179	15	free	free	ADJ
ecletica-1322	179	16	energy	energy	NOUN
ecletica-1322	179	17	function	function	NOUN
ecletica-1322	179	18	comprising	comprise	VERB
ecletica-1322	179	19	intermolecular	intermolecular	ADJ
ecletica-1322	179	20	solvation	solvation	NOUN
ecletica-1322	179	21	and	and	CCONJ
ecletica-1322	179	22	intramolecular	intramolecular	ADJ
ecletica-1322	179	23	self	self	NOUN
ecletica-1322	179	24	-	-	PUNCT
ecletica-1322	179	25	solvation	solvation	NOUN
ecletica-1322	179	26	terms	term	NOUN
ecletica-1322	179	27	.	.	PUNCT
ecletica-1322	180	1	j.	j.	PROPN
ecletica-1322	180	2	cheminformatics	cheminformatics	PROPN
ecletica-1322	180	3	.	.	PUNCT
ecletica-1322	181	1	2013	2013	NUM
ecletica-1322	181	2	,	,	PUNCT
ecletica-1322	181	3	5	5	NUM
ecletica-1322	181	4	,	,	PUNCT
ecletica-1322	181	5	8	8	NUM
ecletica-1322	181	6	.	.	PUNCT
ecletica-1322	182	1	https://doi.org/10.1186/1758-2946-5-8	https://doi.org/10.1186/1758-2946-5-8	PROPN
ecletica-1322	182	2	daina	daina	PROPN
ecletica-1322	182	3	,	,	PUNCT
ecletica-1322	182	4	a.	a.	PROPN
ecletica-1322	182	5	;	;	PUNCT
ecletica-1322	182	6	michielin	michielin	PROPN
ecletica-1322	182	7	,	,	PUNCT
ecletica-1322	182	8	o.	o.	PROPN
ecletica-1322	182	9	;	;	PUNCT
ecletica-1322	182	10	zoete	zoete	NOUN
ecletica-1322	182	11	,	,	PUNCT
ecletica-1322	182	12	v.	v.	CCONJ
ecletica-1322	182	13	swiss	swiss	ADJ
ecletica-1322	182	14	adme	adme	NOUN
ecletica-1322	182	15	:	:	PUNCT
ecletica-1322	182	16	a	a	DET
ecletica-1322	182	17	free	free	ADJ
ecletica-1322	182	18	web	web	NOUN
ecletica-1322	182	19	tool	tool	NOUN
ecletica-1322	182	20	to	to	PART
ecletica-1322	182	21	evaluate	evaluate	VERB
ecletica-1322	182	22	pharmacokinetics	pharmacokinetic	NOUN
ecletica-1322	182	23	,	,	PUNCT
ecletica-1322	182	24	drug	drug	NOUN
ecletica-1322	182	25	-	-	PUNCT
ecletica-1322	182	26	likeness	likeness	NOUN
ecletica-1322	182	27	and	and	CCONJ
ecletica-1322	182	28	medicinal	medicinal	ADJ
ecletica-1322	182	29	chemistry	chemistry	NOUN
ecletica-1322	182	30	friendliness	friendliness	NOUN
ecletica-1322	182	31	of	of	ADP
ecletica-1322	182	32	small	small	ADJ
ecletica-1322	182	33	molecules	molecule	NOUN
ecletica-1322	182	34	.	.	PUNCT
ecletica-1322	183	1	sci	sci	PROPN
ecletica-1322	183	2	.	.	PROPN
ecletica-1322	183	3	rep	rep	PROPN
ecletica-1322	183	4	.	.	PROPN
ecletica-1322	183	5	2017	2017	NUM
ecletica-1322	183	6	,	,	PUNCT
ecletica-1322	183	7	7	7	NUM
ecletica-1322	183	8	,	,	PUNCT
ecletica-1322	183	9	42717	42717	NUM
ecletica-1322	183	10	.	.	PUNCT
ecletica-1322	184	1	https://doi.org/10.1038/srep42717	https://doi.org/10.1038/srep42717	PROPN
ecletica-1322	184	2	erazua	erazua	PROPN
ecletica-1322	184	3	,	,	PUNCT
ecletica-1322	184	4	e.	e.	PROPN
ecletica-1322	184	5	a.	a.	PROPN
ecletica-1322	184	6	;	;	PUNCT
ecletica-1322	184	7	akintelu	akintelu	PROPN
ecletica-1322	184	8	,	,	PUNCT
ecletica-1322	184	9	s.	s.	PROPN
ecletica-1322	184	10	a.	a.	PROPN
ecletica-1322	184	11	;	;	PUNCT
ecletica-1322	184	12	adelowo	adelowo	PROPN
ecletica-1322	184	13	,	,	PUNCT
ecletica-1322	184	14	j.	j.	PROPN
ecletica-1322	184	15	m.	m.	PROPN
ecletica-1322	184	16	;	;	PUNCT
ecletica-1322	184	17	odoemene	odoemene	ADJ
ecletica-1322	184	18	,	,	PUNCT
ecletica-1322	184	19	s.	s.	PROPN
ecletica-1322	184	20	n.	n.	PROPN
ecletica-1322	184	21	;	;	PUNCT
ecletica-1322	184	22	josiah	josiah	PROPN
ecletica-1322	184	23	,	,	PUNCT
ecletica-1322	184	24	o.	o.	PROPN
ecletica-1322	184	25	m.	m.	NOUN
ecletica-1322	184	26	;	;	PUNCT
ecletica-1322	184	27	raheem	raheem	PROPN
ecletica-1322	184	28	,	,	PUNCT
ecletica-1322	184	29	s.	s.	PROPN
ecletica-1322	184	30	f.	f.	PROPN
ecletica-1322	184	31	;	;	PUNCT
ecletica-1322	184	32	latona	latona	PROPN
ecletica-1322	184	33	,	,	PUNCT
ecletica-1322	184	34	d.	d.	PROPN
ecletica-1322	184	35	f.	f.	PROPN
ecletica-1322	184	36	;	;	PUNCT
ecletica-1322	184	37	adeoye	adeoye	PROPN
ecletica-1322	184	38	,	,	PUNCT
ecletica-1322	184	39	m.	m.	PROPN
ecletica-1322	184	40	d.	d.	PROPN
ecletica-1322	184	41	;	;	PUNCT
ecletica-1322	185	1	esan	esan	PROPN
ecletica-1322	185	2	,	,	PUNCT
ecletica-1322	185	3	a.	a.	NOUN
ecletica-1322	185	4	o.	o.	PROPN
ecletica-1322	185	5	;	;	PUNCT
ecletica-1322	185	6	oyebamiji	oyebamiji	PROPN
ecletica-1322	185	7	,	,	PUNCT
ecletica-1322	185	8	a.	a.	PROPN
ecletica-1322	185	9	k.	k.	PROPN
ecletica-1322	185	10	qsar	qsar	PROPN
ecletica-1322	185	11	and	and	CCONJ
ecletica-1322	185	12	molecular	molecular	ADJ
ecletica-1322	185	13	docking	docking	NOUN
ecletica-1322	185	14	studies	study	NOUN
ecletica-1322	185	15	on	on	ADP
ecletica-1322	185	16	nitro(triazole	nitro(triazole	PROPN
ecletica-1322	185	17	/	/	SYM
ecletica-1322	185	18	imidazole)-based	imidazole)-base	VERB
ecletica-1322	185	19	compounds	compound	NOUN
ecletica-1322	185	20	as	as	ADP
ecletica-1322	185	21	anti	anti	ADJ
ecletica-1322	185	22	-	-	ADJ
ecletica-1322	185	23	tubercular	tubercular	ADJ
ecletica-1322	185	24	agents	agent	NOUN
ecletica-1322	185	25	.	.	PUNCT
ecletica-1322	186	1	trop	trop	X
ecletica-1322	186	2	.	.	PUNCT
ecletica-1322	187	1	j.	j.	PROPN
ecletica-1322	187	2	nat	nat	PROPN
ecletica-1322	187	3	.	.	PUNCT
ecletica-1322	188	1	prod	prod	PROPN
ecletica-1322	188	2	.	.	PUNCT
ecletica-1322	189	1	res	re	NOUN
ecletica-1322	189	2	.	.	PROPN
ecletica-1322	189	3	2021	2021	NUM
ecletica-1322	189	4	,	,	PUNCT
ecletica-1322	189	5	5	5	NUM
ecletica-1322	189	6	(	(	PUNCT
ecletica-1322	189	7	11	11	NUM
ecletica-1322	189	8	)	)	PUNCT
ecletica-1322	189	9	,	,	PUNCT
ecletica-1322	189	10	2022–2029	2022–2029	NUM
ecletica-1322	189	11	.	.	PUNCT
ecletica-1322	190	1	https://doi.org/10.26538/tjnpr/v5i11.22	https://doi.org/10.26538/tjnpr/v5i11.22	NOUN
ecletica-1322	190	2	forli	forli	NOUN
ecletica-1322	190	3	,	,	PUNCT
ecletica-1322	190	4	s.	s.	PROPN
ecletica-1322	190	5	;	;	PUNCT
ecletica-1322	190	6	huey	huey	PROPN
ecletica-1322	190	7	,	,	PUNCT
ecletica-1322	190	8	r.	r.	PROPN
ecletica-1322	190	9	;	;	PUNCT
ecletica-1322	190	10	pique	pique	NOUN
ecletica-1322	190	11	,	,	PUNCT
ecletica-1322	190	12	m.	m.	NOUN
ecletica-1322	190	13	;	;	PUNCT
ecletica-1322	190	14	sanner	sanner	NOUN
ecletica-1322	190	15	,	,	PUNCT
ecletica-1322	190	16	m.	m.	NOUN
ecletica-1322	190	17	f.	f.	PROPN
ecletica-1322	190	18	;	;	PUNCT
ecletica-1322	191	1	goodsell	goodsell	PROPN
ecletica-1322	191	2	,	,	PUNCT
ecletica-1322	191	3	d.	d.	PROPN
ecletica-1322	191	4	s.	s.	PROPN
ecletica-1322	191	5	;	;	PUNCT
ecletica-1322	191	6	olson	olson	NOUN
ecletica-1322	191	7	,	,	PUNCT
ecletica-1322	191	8	a.	a.	NOUN
ecletica-1322	191	9	computational	computational	ADJ
ecletica-1322	191	10	protein	protein	NOUN
ecletica-1322	191	11	-	-	PUNCT
ecletica-1322	191	12	ligand	ligand	NOUN
ecletica-1322	191	13	docking	docking	NOUN
ecletica-1322	191	14	and	and	CCONJ
ecletica-1322	191	15	virtual	virtual	ADJ
ecletica-1322	191	16	drug	drug	NOUN
ecletica-1322	191	17	screening	screening	NOUN
ecletica-1322	191	18	with	with	ADP
ecletica-1322	191	19	the	the	DET
ecletica-1322	191	20	autodock	autodock	NOUN
ecletica-1322	191	21	suite	suite	NOUN
ecletica-1322	191	22	.	.	PUNCT
ecletica-1322	192	1	nat	nat	PROPN
ecletica-1322	192	2	.	.	PUNCT
ecletica-1322	193	1	protoc	protoc	VERB
ecletica-1322	193	2	.	.	PUNCT
ecletica-1322	194	1	2016	2016	NUM
ecletica-1322	194	2	,	,	PUNCT
ecletica-1322	194	3	11	11	NUM
ecletica-1322	194	4	(	(	PUNCT
ecletica-1322	194	5	5	5	NUM
ecletica-1322	194	6	)	)	PUNCT
ecletica-1322	194	7	,	,	PUNCT
ecletica-1322	194	8	905–919	905–919	NUM
ecletica-1322	194	9	.	.	PUNCT
ecletica-1322	195	1	https://doi.org/10.1038/nprot.2016.051	https://doi.org/10.1038/nprot.2016.051	ADJ
ecletica-1322	195	2	gao	gao	PROPN
ecletica-1322	195	3	,	,	PUNCT
ecletica-1322	195	4	q.	q.	PROPN
ecletica-1322	195	5	;	;	PUNCT
ecletica-1322	195	6	yang	yang	PROPN
ecletica-1322	195	7	,	,	PUNCT
ecletica-1322	195	8	l.	l.	PROPN
ecletica-1322	195	9	;	;	PUNCT
ecletica-1322	195	10	zhu	zhu	PROPN
ecletica-1322	195	11	,	,	PUNCT
ecletica-1322	195	12	y.	y.	PROPN
ecletica-1322	195	13	pharmacophore	pharmacophore	PROPN
ecletica-1322	195	14	based	base	VERB
ecletica-1322	195	15	drug	drug	NOUN
ecletica-1322	195	16	design	design	NOUN
ecletica-1322	195	17	approach	approach	NOUN
ecletica-1322	195	18	as	as	ADP
ecletica-1322	195	19	a	a	DET
ecletica-1322	195	20	practical	practical	ADJ
ecletica-1322	195	21	process	process	NOUN
ecletica-1322	195	22	in	in	ADP
ecletica-1322	195	23	drug	drug	NOUN
ecletica-1322	195	24	discovery	discovery	NOUN
ecletica-1322	195	25	.	.	PUNCT
ecletica-1322	196	1	curr	curr	PROPN
ecletica-1322	196	2	.	.	PUNCT
ecletica-1322	196	3	comput.-aided	comput.-aided	PROPN
ecletica-1322	196	4	drug	drug	NOUN
ecletica-1322	196	5	des	des	PROPN
ecletica-1322	196	6	.	.	PROPN
ecletica-1322	196	7	2010	2010	NUM
ecletica-1322	196	8	,	,	PUNCT
ecletica-1322	196	9	6	6	NUM
ecletica-1322	196	10	(	(	PUNCT
ecletica-1322	196	11	1	1	NUM
ecletica-1322	196	12	)	)	PUNCT
ecletica-1322	196	13	,	,	PUNCT
ecletica-1322	196	14	37–49	37–49	NUM
ecletica-1322	196	15	.	.	PUNCT
ecletica-1322	197	1	https://doi.org/10.2174/157340910790980151	https://doi.org/10.2174/157340910790980151	PRON
ecletica-1322	197	2	ghotaslou	ghotaslou	NOUN
ecletica-1322	197	3	,	,	PUNCT
ecletica-1322	197	4	r.	r.	PROPN
ecletica-1322	197	5	;	;	PUNCT
ecletica-1322	197	6	leylabadlo	leylabadlo	PROPN
ecletica-1322	197	7	,	,	PUNCT
ecletica-1322	197	8	h.	h.	PROPN
ecletica-1322	197	9	e.	e.	PROPN
ecletica-1322	197	10	;	;	PUNCT
ecletica-1322	197	11	asl	asl	PROPN
ecletica-1322	197	12	,	,	PUNCT
ecletica-1322	197	13	y.	y.	PROPN
ecletica-1322	197	14	m.	m.	PROPN
ecletica-1322	197	15	prevalence	prevalence	NOUN
ecletica-1322	197	16	of	of	ADP
ecletica-1322	197	17	antibiotic	antibiotic	ADJ
ecletica-1322	197	18	resistance	resistance	NOUN
ecletica-1322	197	19	in	in	ADP
ecletica-1322	197	20	helicobacter	helicobacter	NOUN
ecletica-1322	197	21	pylori	pylori	NOUN
ecletica-1322	197	22	:	:	PUNCT
ecletica-1322	197	23	a	a	DET
ecletica-1322	197	24	recent	recent	ADJ
ecletica-1322	197	25	literature	literature	NOUN
ecletica-1322	197	26	review	review	NOUN
ecletica-1322	197	27	.	.	PUNCT
ecletica-1322	198	1	world	world	PROPN
ecletica-1322	198	2	j.	j.	PROPN
ecletica-1322	198	3	methodol	methodol	PROPN
ecletica-1322	198	4	.	.	PUNCT
ecletica-1322	199	1	2015	2015	NUM
ecletica-1322	199	2	,	,	PUNCT
ecletica-1322	199	3	5	5	NUM
ecletica-1322	199	4	(	(	PUNCT
ecletica-1322	199	5	3	3	NUM
ecletica-1322	199	6	)	)	PUNCT
ecletica-1322	199	7	,	,	PUNCT
ecletica-1322	199	8	164–174	164–174	NUM
ecletica-1322	199	9	.	.	PUNCT
ecletica-1322	200	1	https://doi.org/10.5662/wjm.v5.i3.164	https://doi.org/10.5662/wjm.v5.i3.164	PROPN
ecletica-1322	200	2	houghton	houghton	PROPN
ecletica-1322	200	3	,	,	PUNCT
ecletica-1322	200	4	j.	j.	PROPN
ecletica-1322	200	5	m.	m.	PROPN
ecletica-1322	200	6	;	;	PUNCT
ecletica-1322	200	7	wang	wang	PROPN
ecletica-1322	200	8	,	,	PUNCT
ecletica-1322	200	9	t.	t.	PROPN
ecletica-1322	200	10	c.	c.	PROPN
ecletica-1322	200	11	helicobacter	helicobacter	NOUN
ecletica-1322	200	12	pylori	pylori	NOUN
ecletica-1322	200	13	and	and	CCONJ
ecletica-1322	200	14	gastric	gastric	ADJ
ecletica-1322	200	15	cancer	cancer	NOUN
ecletica-1322	200	16	:	:	PUNCT
ecletica-1322	200	17	a	a	DET
ecletica-1322	200	18	new	new	ADJ
ecletica-1322	200	19	paradigm	paradigm	NOUN
ecletica-1322	200	20	for	for	ADP
ecletica-1322	200	21	inflammation	inflammation	NOUN
ecletica-1322	200	22	-	-	PUNCT
ecletica-1322	200	23	associated	associate	VERB
ecletica-1322	200	24	epithelial	epithelial	ADJ
ecletica-1322	200	25	cancers	cancer	NOUN
ecletica-1322	200	26	.	.	PUNCT
ecletica-1322	201	1	gastroenterology	gastroenterology	NOUN
ecletica-1322	201	2	.	.	PUNCT
ecletica-1322	202	1	2005	2005	NUM
ecletica-1322	202	2	,	,	PUNCT
ecletica-1322	202	3	128	128	NUM
ecletica-1322	202	4	(	(	PUNCT
ecletica-1322	202	5	6	6	NUM
ecletica-1322	202	6	)	)	PUNCT
ecletica-1322	202	7	,	,	PUNCT
ecletica-1322	202	8	1567	1567	NUM
ecletica-1322	202	9	–	–	PUNCT
ecletica-1322	202	10	1578	1578	NUM
ecletica-1322	202	11	.	.	PUNCT
ecletica-1322	203	1	https://doi.org/10.1053/j.gastro.2005.03.037	https://doi.org/10.1053/j.gastro.2005.03.037	ADJ
ecletica-1322	203	2	ibrahim	ibrahim	NOUN
ecletica-1322	203	3	,	,	PUNCT
ecletica-1322	203	4	a.	a.	NOUN
ecletica-1322	203	5	o.	o.	PROPN
ecletica-1322	203	6	;	;	PUNCT
ecletica-1322	203	7	oyebamiji	oyebamiji	PROPN
ecletica-1322	203	8	,	,	PUNCT
ecletica-1322	203	9	a.	a.	PROPN
ecletica-1322	203	10	k.	k.	PROPN
ecletica-1322	203	11	;	;	PUNCT
ecletica-1322	203	12	semire	semire	PROPN
ecletica-1322	203	13	,	,	PUNCT
ecletica-1322	203	14	b.	b.	PROPN
ecletica-1322	203	15	computational	computational	ADJ
ecletica-1322	203	16	investigations	investigation	NOUN
ecletica-1322	203	17	on	on	ADP
ecletica-1322	203	18	stability	stability	NOUN
ecletica-1322	203	19	and	and	CCONJ
ecletica-1322	203	20	equilibrium	equilibrium	NOUN
ecletica-1322	203	21	composition	composition	NOUN
ecletica-1322	203	22	of	of	ADP
ecletica-1322	203	23	(	(	PUNCT
ecletica-1322	203	24	z)-indol-3	z)-indol-3	NOUN
ecletica-1322	203	25	-	-	PUNCT
ecletica-1322	203	26	ylidenemethanol	ylidenemethanol	NOUN
ecletica-1322	203	27	:	:	PUNCT
ecletica-1322	203	28	an	an	DET
ecletica-1322	203	29	enol	enol	NOUN
ecletica-1322	203	30	-	-	PUNCT
ecletica-1322	203	31	tautomer	tautomer	NOUN
ecletica-1322	203	32	of	of	ADP
ecletica-1322	203	33	1h	1h	NUM
ecletica-1322	203	34	-	-	PUNCT
ecletica-1322	203	35	indole3	indole3	PROPN
ecletica-1322	203	36	-	-	PUNCT
ecletica-1322	203	37	carbaldehyde	carbaldehyde	NOUN
ecletica-1322	203	38	via	via	ADP
ecletica-1322	203	39	dft	dft	PROPN
ecletica-1322	203	40	approach	approach	NOUN
ecletica-1322	203	41	.	.	PUNCT
ecletica-1322	204	1	curr	curr	PROPN
ecletica-1322	204	2	.	.	PUNCT
ecletica-1322	205	1	phys	phy	NOUN
ecletica-1322	205	2	.	.	PUNCT
ecletica-1322	206	1	chem	chem	NOUN
ecletica-1322	206	2	.	.	PUNCT
ecletica-1322	207	1	2018	2018	NUM
ecletica-1322	207	2	,	,	PUNCT
ecletica-1322	207	3	8	8	NUM
ecletica-1322	207	4	(	(	PUNCT
ecletica-1322	207	5	3	3	NUM
ecletica-1322	207	6	)	)	PUNCT
ecletica-1322	207	7	,	,	PUNCT
ecletica-1322	207	8	194–210	194–210	NUM
ecletica-1322	207	9	.	.	PUNCT
ecletica-1322	208	1	https://doi.org/10.2174/1877946809666181212113209	https://doi.org/10.2174/1877946809666181212113209	PROPN
ecletica-1322	208	2	ibrahim	ibrahim	PROPN
ecletica-1322	208	3	,	,	PUNCT
ecletica-1322	208	4	a.	a.	PROPN
ecletica-1322	208	5	o.	o.	PROPN
ecletica-1322	208	6	;	;	PUNCT
ecletica-1322	208	7	oyebamiji	oyebamiji	PROPN
ecletica-1322	208	8	,	,	PUNCT
ecletica-1322	208	9	a.	a.	PROPN
ecletica-1322	208	10	k.	k.	PROPN
ecletica-1322	208	11	;	;	PUNCT
ecletica-1322	208	12	semire	semire	PROPN
ecletica-1322	208	13	,	,	PUNCT
ecletica-1322	208	14	b.	b.	PROPN
ecletica-1322	208	15	thermodynamics	thermodynamic	NOUN
ecletica-1322	208	16	and	and	CCONJ
ecletica-1322	208	17	kinetics	kinetic	NOUN
ecletica-1322	208	18	of	of	ADP
ecletica-1322	208	19	hydrogen	hydrogen	NOUN
ecletica-1322	208	20	transfer	transfer	NOUN
ecletica-1322	208	21	mechanism	mechanism	NOUN
ecletica-1322	208	22	in	in	ADP
ecletica-1322	208	23	1-[(e)-1,3	1-[(e)-1,3	NUM
ecletica-1322	208	24	-	-	PUNCT
ecletica-1322	208	25	benzothiazol-2	benzothiazol-2	PROPN
ecletica-1322	208	26	-	-	PUNCT
ecletica-1322	208	27	ylazo]naphthalen-2ol	ylazo]naphthalen-2ol	PROPN
ecletica-1322	208	28	tautomers	tautomer	NOUN
ecletica-1322	208	29	in	in	ADP
ecletica-1322	208	30	aqueous	aqueous	ADJ
ecletica-1322	208	31	medium	medium	NOUN
ecletica-1322	208	32	:	:	PUNCT
ecletica-1322	208	33	density	density	NOUN
ecletica-1322	208	34	functional	functional	ADJ
ecletica-1322	208	35	theory	theory	NOUN
ecletica-1322	208	36	.	.	PUNCT
ecletica-1322	209	1	iraqi	iraqi	ADJ
ecletica-1322	209	2	j.	j.	PROPN
ecletica-1322	209	3	sci	sci	PROPN
ecletica-1322	209	4	.	.	PROPN
ecletica-1322	209	5	2019	2019	NUM
ecletica-1322	209	6	,	,	PUNCT
ecletica-1322	209	7	60	60	NUM
ecletica-1322	209	8	(	(	PUNCT
ecletica-1322	209	9	4	4	NUM
ecletica-1322	209	10	)	)	PUNCT
ecletica-1322	209	11	,	,	PUNCT
ecletica-1322	209	12	677–687	677–687	NUM
ecletica-1322	209	13	.	.	PUNCT
ecletica-1322	210	1	iwaloye	iwaloye	NOUN
ecletica-1322	210	2	,	,	PUNCT
ecletica-1322	210	3	o.	o.	PROPN
ecletica-1322	210	4	;	;	PUNCT
ecletica-1322	210	5	elekofehinti	elekofehinti	ADV
ecletica-1322	210	6	,	,	PUNCT
ecletica-1322	210	7	o.	o.	PROPN
ecletica-1322	210	8	o.	o.	PROPN
ecletica-1322	210	9	;	;	PUNCT
ecletica-1322	210	10	kikiowo	kikiowo	PROPN
ecletica-1322	210	11	,	,	PUNCT
ecletica-1322	210	12	b.	b.	PROPN
ecletica-1322	210	13	;	;	PUNCT
ecletica-1322	210	14	fadipe	fadipe	PROPN
ecletica-1322	210	15	,	,	PUNCT
ecletica-1322	210	16	t.	t.	NOUN
ecletica-1322	210	17	m.	m.	NOUN
ecletica-1322	210	18	;	;	PUNCT
ecletica-1322	210	19	akinjiyan	akinjiyan	ADJ
ecletica-1322	210	20	,	,	PUNCT
ecletica-1322	210	21	m.	m.	NOUN
ecletica-1322	210	22	o.	o.	PROPN
ecletica-1322	210	23	;	;	PUNCT
ecletica-1322	210	24	ariyo	ariyo	PROPN
ecletica-1322	210	25	,	,	PUNCT
ecletica-1322	210	26	e.	e.	PROPN
ecletica-1322	210	27	o.	o.	PROPN
ecletica-1322	210	28	;	;	PUNCT
ecletica-1322	210	29	aiyeku	aiyeku	PROPN
ecletica-1322	210	30	,	,	PUNCT
ecletica-1322	210	31	o.	o.	PROPN
ecletica-1322	210	32	o.	o.	PROPN
ecletica-1322	210	33	;	;	PUNCT
ecletica-1322	210	34	adewumi	adewumi	PROPN
ecletica-1322	210	35	,	,	PUNCT
ecletica-1322	210	36	n.	n.	NOUN
ecletica-1322	210	37	a.	a.	NOUN
ecletica-1322	210	38	discovery	discovery	PROPN
ecletica-1322	210	39	of	of	ADP
ecletica-1322	210	40	traditional	traditional	ADJ
ecletica-1322	210	41	chinese	chinese	ADJ
ecletica-1322	210	42	medicine	medicine	NOUN
ecletica-1322	210	43	derived	derive	VERB
ecletica-1322	210	44	compounds	compound	NOUN
ecletica-1322	210	45	as	as	ADP
ecletica-1322	210	46	wild	wild	ADJ
ecletica-1322	210	47	type	type	NOUN
ecletica-1322	210	48	and	and	CCONJ
ecletica-1322	210	49	mutant	mutant	ADJ
ecletica-1322	210	50	plasmodium	plasmodium	NOUN
ecletica-1322	210	51	falciparum	falciparum	ADJ
ecletica-1322	210	52	dihydrofolate	dihydrofolate	NOUN
ecletica-1322	210	53	reductase	reductase	NOUN
ecletica-1322	210	54	inhibitors	inhibitor	NOUN
ecletica-1322	210	55	:	:	PUNCT
ecletica-1322	210	56	induced	induce	VERB
ecletica-1322	210	57	fit	fit	ADJ
ecletica-1322	210	58	docking	docking	NOUN
ecletica-1322	210	59	and	and	CCONJ
ecletica-1322	210	60	adme	adme	NOUN
ecletica-1322	210	61	studies	study	NOUN
ecletica-1322	210	62	.	.	PUNCT
ecletica-1322	211	1	curr	curr	PROPN
ecletica-1322	211	2	.	.	PUNCT
ecletica-1322	211	3	drug	drug	NOUN
ecletica-1322	211	4	discov	discov	PROPN
ecletica-1322	211	5	.	.	PUNCT
ecletica-1322	212	1	technol	technol	NOUN
ecletica-1322	212	2	.	.	PROPN
ecletica-1322	212	3	2021	2021	NUM
ecletica-1322	212	4	,	,	PUNCT
ecletica-1322	212	5	18	18	NUM
ecletica-1322	212	6	(	(	PUNCT
ecletica-1322	212	7	4	4	NUM
ecletica-1322	212	8	)	)	PUNCT
ecletica-1322	212	9	,	,	PUNCT
ecletica-1322	212	10	554–569	554–569	NUM
ecletica-1322	212	11	.	.	PUNCT
ecletica-1322	212	12	https://doi.org/10.2174/1570163817999200729122753	https://doi.org/10.2174/1570163817999200729122753	PROPN
ecletica-1322	212	13	jemilohun	jemilohun	PROPN
ecletica-1322	212	14	,	,	PUNCT
ecletica-1322	212	15	a.	a.	PROPN
ecletica-1322	212	16	c.	c.	PROPN
ecletica-1322	212	17	otegbayo	otegbayo	PROPN
ecletica-1322	212	18	,	,	PUNCT
ecletica-1322	212	19	j.	j.	PROPN
ecletica-1322	212	20	a.	a.	NOUN
ecletica-1322	212	21	helicobacter	helicobacter	PROPN
ecletica-1322	212	22	pylori	pylori	NOUN
ecletica-1322	212	23	infection	infection	NOUN
ecletica-1322	212	24	:	:	PUNCT
ecletica-1322	213	1	past	past	ADJ
ecletica-1322	213	2	,	,	PUNCT
ecletica-1322	213	3	present	present	ADJ
ecletica-1322	213	4	and	and	CCONJ
ecletica-1322	213	5	future	future	NOUN
ecletica-1322	213	6	.	.	PUNCT
ecletica-1322	214	1	pan	pan	PROPN
ecletica-1322	214	2	afr	afr	PROPN
ecletica-1322	214	3	.	.	PUNCT
ecletica-1322	214	4	med	med	PROPN
ecletica-1322	214	5	.	.	PUNCT
ecletica-1322	215	1	j.	j.	PROPN
ecletica-1322	215	2	2016	2016	NUM
ecletica-1322	215	3	,	,	PUNCT
ecletica-1322	215	4	23	23	NUM
ecletica-1322	215	5	,	,	PUNCT
ecletica-1322	215	6	216	216	NUM
ecletica-1322	215	7	.	.	PUNCT
ecletica-1322	216	1	https://doi.org/10.11604/pamj.2016.23.216.8852	https://doi.org/10.11604/pamj.2016.23.216.8852	PROPN
ecletica-1322	216	2	kayali	kayali	PROPN
ecletica-1322	216	3	,	,	PUNCT
ecletica-1322	216	4	s.	s.	PROPN
ecletica-1322	216	5	;	;	PUNCT
ecletica-1322	216	6	manfredi	manfredi	PROPN
ecletica-1322	216	7	,	,	PUNCT
ecletica-1322	216	8	m.	m.	NOUN
ecletica-1322	216	9	;	;	PUNCT
ecletica-1322	216	10	gaiani	gaiani	PROPN
ecletica-1322	216	11	,	,	PUNCT
ecletica-1322	216	12	f.	f.	PROPN
ecletica-1322	216	13	;	;	PUNCT
ecletica-1322	216	14	bianchi	bianchi	PROPN
ecletica-1322	216	15	,	,	PUNCT
ecletica-1322	216	16	l.	l.	PROPN
ecletica-1322	216	17	;	;	PUNCT
ecletica-1322	216	18	bizzarri	bizzarri	PROPN
ecletica-1322	216	19	,	,	PUNCT
ecletica-1322	216	20	b.	b.	PROPN
ecletica-1322	216	21	;	;	PUNCT
ecletica-1322	216	22	leandro	leandro	PROPN
ecletica-1322	216	23	,	,	PUNCT
ecletica-1322	216	24	g.	g.	PROPN
ecletica-1322	216	25	;	;	PUNCT
ecletica-1322	216	26	di	di	PROPN
ecletica-1322	216	27	mario	mario	PROPN
ecletica-1322	216	28	,	,	PUNCT
ecletica-1322	216	29	f.	f.	PROPN
ecletica-1322	216	30	;	;	PUNCT
ecletica-1322	216	31	de	de	X
ecletica-1322	216	32	’	'	PUNCT
ecletica-1322	216	33	angelis	angeli	NOUN
ecletica-1322	216	34	,	,	PUNCT
ecletica-1322	216	35	g.	g.	PROPN
ecletica-1322	216	36	l.	l.	PROPN
ecletica-1322	216	37	helicobacter	helicobacter	PROPN
ecletica-1322	216	38	pylori	pylori	NOUN
ecletica-1322	216	39	,	,	PUNCT
ecletica-1322	216	40	transmission	transmission	NOUN
ecletica-1322	216	41	routes	route	NOUN
ecletica-1322	216	42	and	and	CCONJ
ecletica-1322	216	43	recurrence	recurrence	NOUN
ecletica-1322	216	44	of	of	ADP
ecletica-1322	216	45	infection	infection	NOUN
ecletica-1322	216	46	:	:	PUNCT
ecletica-1322	216	47	state	state	NOUN
ecletica-1322	216	48	of	of	ADP
ecletica-1322	216	49	the	the	DET
ecletica-1322	216	50	art	art	NOUN
ecletica-1322	216	51	.	.	PUNCT
ecletica-1322	217	1	acta	acta	PROPN
ecletica-1322	217	2	.	.	PROPN
ecletica-1322	217	3	biomed	biome	VERB
ecletica-1322	217	4	.	.	PUNCT
ecletica-1322	218	1	2018	2018	NUM
ecletica-1322	218	2	,	,	PUNCT
ecletica-1322	218	3	89	89	NUM
ecletica-1322	218	4	(	(	PUNCT
ecletica-1322	218	5	8	8	NUM
ecletica-1322	218	6	-	-	PUNCT
ecletica-1322	218	7	s	s	NOUN
ecletica-1322	218	8	)	)	PUNCT
ecletica-1322	218	9	,	,	PUNCT
ecletica-1322	218	10	72–76	72–76	NUM
ecletica-1322	218	11	.	.	PUNCT
ecletica-1322	219	1	https://doi.org/10.23750/abm.v89i8-s.7947	https://doi.org/10.23750/abm.v89i8-s.7947	PROPN
ecletica-1322	219	2	kim	kim	PROPN
ecletica-1322	219	3	,	,	PUNCT
ecletica-1322	219	4	y.	y.	PROPN
ecletica-1322	219	5	;	;	PUNCT
ecletica-1322	219	6	lee	lee	PROPN
ecletica-1322	219	7	,	,	PUNCT
ecletica-1322	219	8	k.	k.	PROPN
ecletica-1322	219	9	h.	h.	PROPN
ecletica-1322	219	10	;	;	PUNCT
ecletica-1322	219	11	kim	kim	PROPN
ecletica-1322	219	12	,	,	PUNCT
ecletica-1322	219	13	j.-h	j.-h	PROPN
ecletica-1322	219	14	.	.	PUNCT
ecletica-1322	219	15	;	;	PUNCT
ecletica-1322	219	16	park	park	NOUN
ecletica-1322	219	17	,	,	PUNCT
ecletica-1322	219	18	s.	s.	PROPN
ecletica-1322	219	19	p.	p.	PROPN
ecletica-1322	219	20	;	;	PUNCT
ecletica-1322	219	21	song	song	NOUN
ecletica-1322	219	22	,	,	PUNCT
ecletica-1322	219	23	y.	y.	PROPN
ecletica-1322	219	24	g.	g.	PROPN
ecletica-1322	219	25	;	;	PUNCT
ecletica-1322	219	26	jeon	jeon	PROPN
ecletica-1322	219	27	,	,	PUNCT
ecletica-1322	219	28	s.	s.	PROPN
ecletica-1322	219	29	y.	y.	PROPN
ecletica-1322	219	30	;	;	PUNCT
ecletica-1322	219	31	park	park	PROPN
ecletica-1322	219	32	,	,	PUNCT
ecletica-1322	219	33	h.	h.	PROPN
ecletica-1322	219	34	is	be	AUX
ecletica-1322	219	35	only	only	ADV
ecletica-1322	219	36	clarithromycin	clarithromycin	NOUN
ecletica-1322	219	37	susceptibility	susceptibility	NOUN
ecletica-1322	219	38	important	important	ADJ
ecletica-1322	219	39	for	for	ADP
ecletica-1322	219	40	the	the	DET
ecletica-1322	219	41	successful	successful	ADJ
ecletica-1322	219	42	eradication	eradication	NOUN
ecletica-1322	219	43	of	of	ADP
ecletica-1322	219	44	helicobacter	helicobacter	NOUN
ecletica-1322	219	45	pylori	pylori	NOUN
ecletica-1322	219	46	?	?	PUNCT
ecletica-1322	220	1	antibiotics	antibiotic	NOUN
ecletica-1322	220	2	2020	2020	NUM
ecletica-1322	220	3	,	,	PUNCT
ecletica-1322	220	4	9	9	NUM
ecletica-1322	220	5	(	(	PUNCT
ecletica-1322	220	6	9	9	NUM
ecletica-1322	220	7	)	)	PUNCT
ecletica-1322	220	8	,	,	PUNCT
ecletica-1322	220	9	589	589	NUM
ecletica-1322	220	10	.	.	PUNCT
ecletica-1322	220	11	https://doi.org/10.3390/antibiotics9090589	https://doi.org/10.3390/antibiotics9090589	PROPN
ecletica-1322	220	12	https://revista.iq.unesp.br/index.php/ecletica	https://revista.iq.unesp.br/index.php/ecletica	PROPN
ecletica-1322	220	13	https://doi.org/10.26850/1678-4618eqj.v47.4.2022.p27-36	https://doi.org/10.26850/1678-4618eqj.v47.4.2022.p27-36	VERB
ecletica-1322	220	14	https://doi.org/10.1016/j.dib.2020.105963	https://doi.org/10.1016/j.dib.2020.105963	PROPN
ecletica-1322	220	15	https://doi.org/10.1016/j.dib.2020.105963	https://doi.org/10.1016/j.dib.2020.105963	PROPN
ecletica-1322	220	16	https://doi.org/10.4172/2161-0398.1000213	https://doi.org/10.4172/2161-0398.1000213	PROPN
ecletica-1322	220	17	https://doi.org/10.4172/2161-0398.1000213	https://doi.org/10.4172/2161-0398.1000213	PROPN
ecletica-1322	220	18	https://doi.org/10.4172/2161-0398.1000213	https://doi.org/10.4172/2161-0398.1000213	PROPN
ecletica-1322	220	19	https://doi.org/10.4172/2161-0398.1000213	https://doi.org/10.4172/2161-0398.1000213	PROPN
ecletica-1322	220	20	https://doi.org/10.1016/j.arabjc.2012.06.019	https://doi.org/10.1016/j.arabjc.2012.06.019	PROPN
ecletica-1322	220	21	https://doi.org/10.1016/j.arabjc.2012.06.019	https://doi.org/10.1016/j.arabjc.2012.06.019	PROPN
ecletica-1322	220	22	https://doi.org/10.1016/j.arabjc.2012.06.019	https://doi.org/10.1016/j.arabjc.2012.06.019	PROPN
ecletica-1322	220	23	https://doi.org/10.1016/j.arabjc.2012.06.019	https://doi.org/10.1016/j.arabjc.2012.06.019	PROPN
ecletica-1322	220	24	https://doi.org/10.1016/j.arabjc.2012.06.019	https://doi.org/10.1016/j.arabjc.2012.06.019	PROPN
ecletica-1322	220	25	https://doi.org/10.33263/briac126.74697477	https://doi.org/10.33263/briac126.74697477	NUM
ecletica-1322	220	26	https://doi.org/10.33263/briac126.74697477	https://doi.org/10.33263/briac126.74697477	NUM
ecletica-1322	220	27	https://doi.org/10.33263/briac126.74697477	https://doi.org/10.33263/briac126.74697477	NUM
ecletica-1322	220	28	https://doi.org/10.33263/briac126.74697477	https://doi.org/10.33263/briac126.74697477	NUM
ecletica-1322	220	29	https://doi.org/10.33263/briac126.74697477	https://doi.org/10.33263/briac126.74697477	NUM
ecletica-1322	220	30	https://doi.org/10.26850/1678-4618eqj.v46.2.2021.p17-25	https://doi.org/10.26850/1678-4618eqj.v46.2.2021.p17-25	NUM
ecletica-1322	220	31	https://doi.org/10.26850/1678-4618eqj.v46.2.2021.p17-25	https://doi.org/10.26850/1678-4618eqj.v46.2.2021.p17-25	NUM
ecletica-1322	220	32	https://doi.org/10.26850/1678-4618eqj.v46.2.2021.p17-25	https://doi.org/10.26850/1678-4618eqj.v46.2.2021.p17-25	X
ecletica-1322	220	33	https://doi.org/10.26850/1678-4618eqj.v46.2.2021.p17-25	https://doi.org/10.26850/1678-4618eqj.v46.2.2021.p17-25	X
ecletica-1322	220	34	https://doi.org/10.26850/1678-4618eqj.v46.2.2021.p17-25	https://doi.org/10.26850/1678-4618eqj.v46.2.2021.p17-25	X
ecletica-1322	220	35	https://doi.org/10.1007/s00044-014-1197-4	https://doi.org/10.1007/s00044-014-1197-4	PROPN
ecletica-1322	221	1	https://doi.org/10.1007/s00044-014-1197-4	https://doi.org/10.1007/s00044-014-1197-4	PROPN
ecletica-1322	221	2	https://doi.org/10.1007/s00044-014-1197-4	https://doi.org/10.1007/s00044-014-1197-4	PROPN
ecletica-1322	221	3	https://doi.org/10.1007/s00044-014-1197-4	https://doi.org/10.1007/s00044-014-1197-4	PROPN
ecletica-1322	221	4	https://doi.org/10.1007/s00044-014-1197-4	https://doi.org/10.1007/s00044-014-1197-4	PROPN
ecletica-1322	221	5	https://doi.org/10.1007/s00044-014-1197-4	https://doi.org/10.1007/s00044-014-1197-4	PROPN
ecletica-1322	221	6	https://doi.org/10.2174/156802605774297038	https://doi.org/10.2174/156802605774297038	PROPN
ecletica-1322	221	7	https://doi.org/10.2174/156802605774297038	https://doi.org/10.2174/156802605774297038	PROPN
ecletica-1322	221	8	https://doi.org/10.2174/156802605774297038	https://doi.org/10.2174/156802605774297038	PROPN
ecletica-1322	221	9	https://doi.org/10.2174/156802605774297038	https://doi.org/10.2174/156802605774297038	PROPN
ecletica-1322	221	10	https://doi.org/10.2174/156802605774297038	https://doi.org/10.2174/156802605774297038	NOUN
ecletica-1322	222	1	https://doi.org/10.1111/j.1600-0722.2008.00543.x	https://doi.org/10.1111/j.1600-0722.2008.00543.x	NOUN
ecletica-1322	222	2	https://doi.org/10.1111/j.1600-0722.2008.00543.x	https://doi.org/10.1111/j.1600-0722.2008.00543.x	NOUN
ecletica-1322	222	3	https://doi.org/10.1111/j.1600-0722.2008.00543.x	https://doi.org/10.1111/j.1600-0722.2008.00543.x	NOUN
ecletica-1322	222	4	https://doi.org/10.1111/j.1600-0722.2008.00543.x	https://doi.org/10.1111/j.1600-0722.2008.00543.x	NOUN
ecletica-1322	222	5	https://doi.org/10.1111/j.1600-0722.2008.00543.x	https://doi.org/10.1111/j.1600-0722.2008.00543.x	NOUN
ecletica-1322	222	6	https://doi.org/10.1186/1758-2946-5-8	https://doi.org/10.1186/1758-2946-5-8	PROPN
ecletica-1322	222	7	https://doi.org/10.1186/1758-2946-5-8	https://doi.org/10.1186/1758-2946-5-8	PROPN
ecletica-1322	222	8	https://doi.org/10.1186/1758-2946-5-8	https://doi.org/10.1186/1758-2946-5-8	NOUN
ecletica-1322	223	1	https://doi.org/10.1186/1758-2946-5-8	https://doi.org/10.1186/1758-2946-5-8	PROPN
ecletica-1322	223	2	https://doi.org/10.1038/srep42717	https://doi.org/10.1038/srep42717	PROPN
ecletica-1322	223	3	https://doi.org/10.1038/srep42717	https://doi.org/10.1038/srep42717	PROPN
ecletica-1322	223	4	https://doi.org/10.1038/srep42717	https://doi.org/10.1038/srep42717	PROPN
ecletica-1322	223	5	https://doi.org/10.1038/srep42717	https://doi.org/10.1038/srep42717	PROPN
ecletica-1322	223	6	https://doi.org/10.26538/tjnpr/v5i11.22	https://doi.org/10.26538/tjnpr/v5i11.22	PROPN
ecletica-1322	223	7	https://doi.org/10.26538/tjnpr/v5i11.22	https://doi.org/10.26538/tjnpr/v5i11.22	NOUN
ecletica-1322	223	8	https://doi.org/10.26538/tjnpr/v5i11.22	https://doi.org/10.26538/tjnpr/v5i11.22	NOUN
ecletica-1322	223	9	https://doi.org/10.26538/tjnpr/v5i11.22	https://doi.org/10.26538/tjnpr/v5i11.22	NOUN
ecletica-1322	223	10	https://doi.org/10.26538/tjnpr/v5i11.22	https://doi.org/10.26538/tjnpr/v5i11.22	NOUN
ecletica-1322	223	11	https://doi.org/10.26538/tjnpr/v5i11.22	https://doi.org/10.26538/tjnpr/v5i11.22	NOUN
ecletica-1322	223	12	https://doi.org/10.26538/tjnpr/v5i11.22	https://doi.org/10.26538/tjnpr/v5i11.22	PROPN
ecletica-1322	223	13	https://doi.org/10.1038/nprot.2016.051	https://doi.org/10.1038/nprot.2016.051	PROPN
ecletica-1322	223	14	https://doi.org/10.1038/nprot.2016.051	https://doi.org/10.1038/nprot.2016.051	PROPN
ecletica-1322	223	15	https://doi.org/10.1038/nprot.2016.051	https://doi.org/10.1038/nprot.2016.051	PROPN
ecletica-1322	223	16	https://doi.org/10.1038/nprot.2016.051	https://doi.org/10.1038/nprot.2016.051	PROPN
ecletica-1322	223	17	https://doi.org/10.2174/157340910790980151	https://doi.org/10.2174/157340910790980151	ADV
ecletica-1322	223	18	https://doi.org/10.2174/157340910790980151	https://doi.org/10.2174/157340910790980151	ADV
ecletica-1322	223	19	https://doi.org/10.2174/157340910790980151	https://doi.org/10.2174/157340910790980151	ADV
ecletica-1322	223	20	https://doi.org/10.2174/157340910790980151	https://doi.org/10.2174/157340910790980151	NOUN
ecletica-1322	223	21	https://doi.org/10.5662/wjm.v5.i3.164	https://doi.org/10.5662/wjm.v5.i3.164	NOUN
ecletica-1322	223	22	https://doi.org/10.5662/wjm.v5.i3.164	https://doi.org/10.5662/wjm.v5.i3.164	NOUN
ecletica-1322	223	23	https://doi.org/10.5662/wjm.v5.i3.164	https://doi.org/10.5662/wjm.v5.i3.164	NOUN
ecletica-1322	223	24	https://doi.org/10.5662/wjm.v5.i3.164	https://doi.org/10.5662/wjm.v5.i3.164	NOUN
ecletica-1322	223	25	https://doi.org/10.1053/j.gastro.2005.03.037	https://doi.org/10.1053/j.gastro.2005.03.037	ADJ
ecletica-1322	223	26	https://doi.org/10.1053/j.gastro.2005.03.037	https://doi.org/10.1053/j.gastro.2005.03.037	NOUN
ecletica-1322	223	27	https://doi.org/10.1053/j.gastro.2005.03.037	https://doi.org/10.1053/j.gastro.2005.03.037	NOUN
ecletica-1322	223	28	https://doi.org/10.1053/j.gastro.2005.03.037	https://doi.org/10.1053/j.gastro.2005.03.037	NUM
ecletica-1322	223	29	https://doi.org/10.2174/1877946809666181212113209	https://doi.org/10.2174/1877946809666181212113209	NOUN
ecletica-1322	223	30	https://doi.org/10.2174/1877946809666181212113209	https://doi.org/10.2174/1877946809666181212113209	NOUN
ecletica-1322	223	31	https://doi.org/10.2174/1877946809666181212113209	https://doi.org/10.2174/1877946809666181212113209	NOUN
ecletica-1322	224	1	https://doi.org/10.2174/1877946809666181212113209	https://doi.org/10.2174/1877946809666181212113209	INTJ
ecletica-1322	224	2	https://doi.org/10.2174/1877946809666181212113209	https://doi.org/10.2174/1877946809666181212113209	INTJ
ecletica-1322	224	3	https://doi.org/10.2174/1877946809666181212113209	https://doi.org/10.2174/1877946809666181212113209	PUNCT
ecletica-1322	224	4	https://doi.org/10.2174/1570163817999200729122753	https://doi.org/10.2174/1570163817999200729122753	X
ecletica-1322	224	5	https://doi.org/10.2174/1570163817999200729122753	https://doi.org/10.2174/1570163817999200729122753	X
ecletica-1322	224	6	https://doi.org/10.2174/1570163817999200729122753	https://doi.org/10.2174/1570163817999200729122753	PUNCT
ecletica-1322	224	7	https://doi.org/10.2174/1570163817999200729122753	https://doi.org/10.2174/1570163817999200729122753	PUNCT
ecletica-1322	224	8	https://doi.org/10.2174/1570163817999200729122753	https://doi.org/10.2174/1570163817999200729122753	PUNCT
ecletica-1322	224	9	https://doi.org/10.2174/1570163817999200729122753	https://doi.org/10.2174/1570163817999200729122753	PUNCT
ecletica-1322	224	10	https://doi.org/10.2174/1570163817999200729122753	https://doi.org/10.2174/1570163817999200729122753	X
ecletica-1322	224	11	https://doi.org/10.2174/1570163817999200729122753	https://doi.org/10.2174/1570163817999200729122753	X
ecletica-1322	224	12	https://doi.org/10.11604/pamj.2016.23.216.8852	https://doi.org/10.11604/pamj.2016.23.216.8852	PROPN
ecletica-1322	224	13	https://doi.org/10.11604/pamj.2016.23.216.8852	https://doi.org/10.11604/pamj.2016.23.216.8852	PROPN
ecletica-1322	224	14	https://doi.org/10.11604/pamj.2016.23.216.8852	https://doi.org/10.11604/pamj.2016.23.216.8852	PROPN
ecletica-1322	224	15	https://doi.org/10.23750/abm.v89i8-s.7947	https://doi.org/10.23750/abm.v89i8-s.7947	X
ecletica-1322	224	16	https://doi.org/10.23750/abm.v89i8-s.7947	https://doi.org/10.23750/abm.v89i8-s.7947	PROPN
ecletica-1322	224	17	https://doi.org/10.23750/abm.v89i8-s.7947	https://doi.org/10.23750/abm.v89i8-s.7947	PROPN
ecletica-1322	224	18	https://doi.org/10.23750/abm.v89i8-s.7947	https://doi.org/10.23750/abm.v89i8-s.7947	PROPN
ecletica-1322	224	19	https://doi.org/10.23750/abm.v89i8-s.7947	https://doi.org/10.23750/abm.v89i8-s.7947	PROPN
ecletica-1322	224	20	https://doi.org/10.3390/antibiotics9090589	https://doi.org/10.3390/antibiotics9090589	PROPN
ecletica-1322	224	21	https://doi.org/10.3390/antibiotics9090589	https://doi.org/10.3390/antibiotics9090589	PROPN
ecletica-1322	224	22	https://doi.org/10.3390/antibiotics9090589	https://doi.org/10.3390/antibiotics9090589	PROPN
ecletica-1322	224	23	https://doi.org/10.3390/antibiotics9090589	https://doi.org/10.3390/antibiotics9090589	PROPN
ecletica-1322	224	24	https://doi.org/10.3390/antibiotics9090589	https://doi.org/10.3390/antibiotics9090589	PROPN
ecletica-1322	224	25	original	original	ADJ
ecletica-1322	224	26	article	article	NOUN
ecletica-1322	224	27	revista.iq.unesp.br	revista.iq.unesp.br	VERB
ecletica-1322	224	28	36	36	NUM
ecletica-1322	224	29	eclética	eclética	PROPN
ecletica-1322	224	30	química	química	PROPN
ecletica-1322	224	31	journal	journal	PROPN
ecletica-1322	224	32	,	,	PUNCT
ecletica-1322	224	33	vol	vol	NOUN
ecletica-1322	224	34	.	.	PROPN
ecletica-1322	224	35	47	47	NUM
ecletica-1322	224	36	,	,	PUNCT
ecletica-1322	224	37	n.	n.	NOUN
ecletica-1322	224	38	4	4	NUM
ecletica-1322	224	39	,	,	PUNCT
ecletica-1322	224	40	2022	2022	NUM
ecletica-1322	224	41	,	,	PUNCT
ecletica-1322	224	42	27	27	NUM
ecletica-1322	224	43	-	-	SYM
ecletica-1322	224	44	36	36	NUM
ecletica-1322	224	45	issn	issn	NOUN
ecletica-1322	224	46	:	:	PUNCT
ecletica-1322	224	47	1678	1678	NUM
ecletica-1322	224	48	-	-	SYM
ecletica-1322	224	49	4618	4618	NUM
ecletica-1322	224	50	doi	doi	NOUN
ecletica-1322	224	51	:	:	PUNCT
ecletica-1322	224	52	10.26850/1678	10.26850/1678	NUM
ecletica-1322	224	53	-	-	SYM
ecletica-1322	224	54	4618eqj.v47.4.2022.p27	4618eqj.v47.4.2022.p27	NUM
ecletica-1322	224	55	-	-	PUNCT
ecletica-1322	224	56	36	36	NUM
ecletica-1322	224	57	kulhánek	kulhánek	ADJ
ecletica-1322	224	58	,	,	PUNCT
ecletica-1322	224	59	j.	j.	PROPN
ecletica-1322	224	60	;	;	PUNCT
ecletica-1322	224	61	bureš	bureš	PROPN
ecletica-1322	224	62	,	,	PUNCT
ecletica-1322	224	63	f.	f.	PROPN
ecletica-1322	224	64	imidazole	imidazole	PROPN
ecletica-1322	224	65	as	as	ADP
ecletica-1322	224	66	a	a	DET
ecletica-1322	224	67	parent	parent	NOUN
ecletica-1322	224	68	π	π	NOUN
ecletica-1322	224	69	-	-	PUNCT
ecletica-1322	224	70	conjugated	conjugate	VERB
ecletica-1322	224	71	backbone	backbone	NOUN
ecletica-1322	224	72	in	in	ADP
ecletica-1322	224	73	charge	charge	NOUN
ecletica-1322	224	74	-	-	PUNCT
ecletica-1322	224	75	transfer	transfer	NOUN
ecletica-1322	224	76	chromophores	chromophore	NOUN
ecletica-1322	224	77	.	.	PUNCT
ecletica-1322	225	1	beilstein	beilstein	PROPN
ecletica-1322	225	2	j.	j.	PROPN
ecletica-1322	225	3	org	org	PROPN
ecletica-1322	225	4	.	.	PUNCT
ecletica-1322	226	1	chem	chem	PROPN
ecletica-1322	226	2	.	.	PUNCT
ecletica-1322	227	1	2012	2012	NUM
ecletica-1322	227	2	,	,	PUNCT
ecletica-1322	227	3	8	8	NUM
ecletica-1322	227	4	,	,	PUNCT
ecletica-1322	227	5	25–49	25–49	NUM
ecletica-1322	227	6	.	.	PUNCT
ecletica-1322	228	1	https://doi.org/10.3762/bjoc.8.4	https://doi.org/10.3762/bjoc.8.4	X
ecletica-1322	228	2	lipinski	lipinski	PROPN
ecletica-1322	228	3	,	,	PUNCT
ecletica-1322	228	4	c.	c.	PROPN
ecletica-1322	228	5	a.	a.	PROPN
ecletica-1322	228	6	;	;	PUNCT
ecletica-1322	228	7	lombardo	lombardo	PROPN
ecletica-1322	228	8	,	,	PUNCT
ecletica-1322	228	9	f.	f.	PROPN
ecletica-1322	228	10	;	;	PUNCT
ecletica-1322	228	11	dominy	dominy	PROPN
ecletica-1322	228	12	,	,	PUNCT
ecletica-1322	228	13	b.	b.	PROPN
ecletica-1322	228	14	w.	w.	PROPN
ecletica-1322	228	15	;	;	PUNCT
ecletica-1322	228	16	feeney	feeney	PROPN
ecletica-1322	228	17	,	,	PUNCT
ecletica-1322	228	18	p.	p.	PROPN
ecletica-1322	228	19	j.	j.	PROPN
ecletica-1322	228	20	experimental	experimental	PROPN
ecletica-1322	228	21	and	and	CCONJ
ecletica-1322	228	22	computational	computational	ADJ
ecletica-1322	228	23	approaches	approach	NOUN
ecletica-1322	228	24	to	to	PART
ecletica-1322	228	25	estimate	estimate	VERB
ecletica-1322	228	26	solubility	solubility	NOUN
ecletica-1322	228	27	and	and	CCONJ
ecletica-1322	228	28	permeability	permeability	NOUN
ecletica-1322	228	29	in	in	ADP
ecletica-1322	228	30	drug	drug	NOUN
ecletica-1322	228	31	discovery	discovery	NOUN
ecletica-1322	228	32	and	and	CCONJ
ecletica-1322	228	33	development	development	NOUN
ecletica-1322	228	34	settings	setting	NOUN
ecletica-1322	228	35	.	.	PUNCT
ecletica-1322	229	1	advanced	advanced	ADJ
ecletica-1322	229	2	drug	drug	NOUN
ecletica-1322	229	3	delivery	delivery	NOUN
ecletica-1322	229	4	reviews	review	NOUN
ecletica-1322	229	5	.	.	PUNCT
ecletica-1322	230	1	2001	2001	NUM
ecletica-1322	230	2	,	,	PUNCT
ecletica-1322	230	3	46	46	NUM
ecletica-1322	230	4	,	,	PUNCT
ecletica-1322	230	5	1–3	1–3	NUM
ecletica-1322	230	6	,	,	PUNCT
ecletica-1322	230	7	3–26	3–26	NUM
ecletica-1322	230	8	.	.	PUNCT
ecletica-1322	231	1	https://doi.org/10.1016/s0169409x(00)00129-0	https://doi.org/10.1016/s0169409x(00)00129-0	PROPN
ecletica-1322	231	2	martínez	martínez	NOUN
ecletica-1322	231	3	-	-	PUNCT
ecletica-1322	231	4	júlvez	júlvez	PROPN
ecletica-1322	231	5	,	,	PUNCT
ecletica-1322	231	6	m.	m.	NOUN
ecletica-1322	231	7	;	;	PUNCT
ecletica-1322	231	8	rojas	rojas	PROPN
ecletica-1322	231	9	,	,	PUNCT
ecletica-1322	231	10	a.	a.	PROPN
ecletica-1322	231	11	l.	l.	PROPN
ecletica-1322	231	12	;	;	PUNCT
ecletica-1322	231	13	olekhnovich	olekhnovich	PROPN
ecletica-1322	231	14	,	,	PUNCT
ecletica-1322	231	15	i.	i.	PROPN
ecletica-1322	231	16	;	;	PUNCT
ecletica-1322	231	17	angarica	angarica	PROPN
ecletica-1322	231	18	,	,	PUNCT
ecletica-1322	231	19	v.	v.	PROPN
ecletica-1322	231	20	e.	e.	PROPN
ecletica-1322	231	21	;	;	PUNCT
ecletica-1322	231	22	hoffman	hoffman	PROPN
ecletica-1322	231	23	,	,	PUNCT
ecletica-1322	231	24	p.	p.	PROPN
ecletica-1322	231	25	s.	s.	PROPN
ecletica-1322	231	26	;	;	PUNCT
ecletica-1322	231	27	sancho	sancho	PROPN
ecletica-1322	231	28	,	,	PUNCT
ecletica-1322	231	29	j.	j.	PROPN
ecletica-1322	231	30	structure	structure	PROPN
ecletica-1322	231	31	of	of	ADP
ecletica-1322	231	32	rdxa	rdxa	PROPN
ecletica-1322	231	33	–	–	PUNCT
ecletica-1322	231	34	an	an	DET
ecletica-1322	231	35	oxygen	oxygen	NOUN
ecletica-1322	231	36	-	-	PUNCT
ecletica-1322	231	37	insensitive	insensitive	ADJ
ecletica-1322	231	38	nitroreductase	nitroreductase	NOUN
ecletica-1322	231	39	essential	essential	ADJ
ecletica-1322	231	40	for	for	ADP
ecletica-1322	231	41	metronidazole	metronidazole	NOUN
ecletica-1322	231	42	activation	activation	NOUN
ecletica-1322	231	43	in	in	ADP
ecletica-1322	231	44	helicobacter	helicobacter	NOUN
ecletica-1322	231	45	pylori	pylori	NOUN
ecletica-1322	231	46	.	.	PUNCT
ecletica-1322	232	1	febs	febs	PROPN
ecletica-1322	232	2	j.	j.	PROPN
ecletica-1322	232	3	2012	2012	NUM
ecletica-1322	232	4	,	,	PUNCT
ecletica-1322	232	5	279	279	NUM
ecletica-1322	232	6	,	,	PUNCT
ecletica-1322	232	7	4306	4306	NUM
ecletica-1322	232	8	–	–	PUNCT
ecletica-1322	232	9	4317	4317	NUM
ecletica-1322	232	10	.	.	PUNCT
ecletica-1322	233	1	https://doi.org/10.1111/febs.12020	https://doi.org/10.1111/febs.12020	PROPN
ecletica-1322	233	2	méndez	méndez	PROPN
ecletica-1322	233	3	-	-	PUNCT
ecletica-1322	233	4	lucio	lucio	PROPN
ecletica-1322	233	5	,	,	PUNCT
ecletica-1322	233	6	o.	o.	PROPN
ecletica-1322	233	7	;	;	PUNCT
ecletica-1322	233	8	medina	medina	PROPN
ecletica-1322	233	9	-	-	PUNCT
ecletica-1322	233	10	franco	franco	PROPN
ecletica-1322	233	11	,	,	PUNCT
ecletica-1322	233	12	j.	j.	PROPN
ecletica-1322	233	13	l.	l.	PROPN
ecletica-1322	233	14	the	the	DET
ecletica-1322	233	15	many	many	ADJ
ecletica-1322	233	16	roles	role	NOUN
ecletica-1322	233	17	of	of	ADP
ecletica-1322	233	18	molecular	molecular	ADJ
ecletica-1322	233	19	complexity	complexity	NOUN
ecletica-1322	233	20	in	in	ADP
ecletica-1322	233	21	drug	drug	NOUN
ecletica-1322	233	22	discovery	discovery	NOUN
ecletica-1322	233	23	.	.	PUNCT
ecletica-1322	234	1	drug	drug	NOUN
ecletica-1322	234	2	discov	discov	NOUN
ecletica-1322	234	3	.	.	PUNCT
ecletica-1322	235	1	today	today	NOUN
ecletica-1322	235	2	.	.	PUNCT
ecletica-1322	236	1	2017	2017	NUM
ecletica-1322	236	2	,	,	PUNCT
ecletica-1322	236	3	22	22	NUM
ecletica-1322	236	4	(	(	PUNCT
ecletica-1322	236	5	1	1	NUM
ecletica-1322	236	6	)	)	PUNCT
ecletica-1322	236	7	,	,	PUNCT
ecletica-1322	236	8	122–126	122–126	NUM
ecletica-1322	236	9	https://doi.org/10.1016/j.drudis.2016.08.009	https://doi.org/10.1016/j.drudis.2016.08.009	PROPN
ecletica-1322	236	10	meng	meng	PROPN
ecletica-1322	236	11	,	,	PUNCT
ecletica-1322	236	12	x.-y	x.-y	PROPN
ecletica-1322	236	13	.	.	PUNCT
ecletica-1322	236	14	;	;	PUNCT
ecletica-1322	236	15	zhang	zhang	PROPN
ecletica-1322	236	16	,	,	PUNCT
ecletica-1322	236	17	h.-x	h.-x	NOUN
ecletica-1322	236	18	.	.	PUNCT
ecletica-1322	236	19	;	;	PUNCT
ecletica-1322	237	1	mazei	mazei	VERB
ecletica-1322	237	2	,	,	PUNCT
ecletica-1322	237	3	m.	m.	NOUN
ecletica-1322	237	4	;	;	PUNCT
ecletica-1322	237	5	cui	cui	NOUN
ecletica-1322	237	6	,	,	PUNCT
ecletica-1322	237	7	m.	m.	NOUN
ecletica-1322	237	8	molecular	molecular	ADJ
ecletica-1322	237	9	docking	docking	NOUN
ecletica-1322	237	10	:	:	PUNCT
ecletica-1322	237	11	a	a	DET
ecletica-1322	237	12	powerful	powerful	ADJ
ecletica-1322	237	13	approach	approach	NOUN
ecletica-1322	237	14	for	for	ADP
ecletica-1322	237	15	structure	structure	NOUN
ecletica-1322	237	16	-	-	PUNCT
ecletica-1322	237	17	based	base	VERB
ecletica-1322	237	18	drug	drug	NOUN
ecletica-1322	237	19	discovery	discovery	NOUN
ecletica-1322	237	20	.	.	PUNCT
ecletica-1322	238	1	curr	curr	PROPN
ecletica-1322	238	2	.	.	PUNCT
ecletica-1322	238	3	comput.-aided	comput.-aided	PROPN
ecletica-1322	238	4	drug	drug	NOUN
ecletica-1322	238	5	des	des	PROPN
ecletica-1322	238	6	.	.	PROPN
ecletica-1322	238	7	2011	2011	NUM
ecletica-1322	238	8	,	,	PUNCT
ecletica-1322	238	9	7	7	NUM
ecletica-1322	238	10	(	(	PUNCT
ecletica-1322	238	11	2	2	NUM
ecletica-1322	238	12	)	)	PUNCT
ecletica-1322	238	13	,	,	PUNCT
ecletica-1322	239	1	146	146	NUM
ecletica-1322	239	2	–	–	SYM
ecletica-1322	239	3	157	157	NUM
ecletica-1322	239	4	.	.	PUNCT
ecletica-1322	239	5	https://doi.org/10.2174/157340911795677602	https://doi.org/10.2174/157340911795677602	PROPN
ecletica-1322	239	6	morakinyo	morakinyo	PROPN
ecletica-1322	239	7	,	,	PUNCT
ecletica-1322	239	8	a.	a.	PROPN
ecletica-1322	239	9	e.	e.	PROPN
ecletica-1322	239	10	;	;	PUNCT
ecletica-1322	239	11	omoniyi	omoniyi	PROPN
ecletica-1322	239	12	,	,	PUNCT
ecletica-1322	239	13	f.	f.	PROPN
ecletica-1322	239	14	e.	e.	PROPN
ecletica-1322	239	15	;	;	PUNCT
ecletica-1322	239	16	nzekwe	nzekwe	VERB
ecletica-1322	239	17	,	,	PUNCT
ecletica-1322	239	18	s.	s.	PROPN
ecletica-1322	239	19	c.	c.	PROPN
ecletica-1322	239	20	;	;	PUNCT
ecletica-1322	239	21	oyebamiji	oyebamiji	PROPN
ecletica-1322	239	22	a.	a.	PROPN
ecletica-1322	239	23	k.	k.	PROPN
ecletica-1322	239	24	;	;	PUNCT
ecletica-1322	239	25	adelowo	adelowo	PROPN
ecletica-1322	239	26	,	,	PUNCT
ecletica-1322	239	27	j.	j.	PROPN
ecletica-1322	239	28	m.	m.	PROPN
ecletica-1322	239	29	;	;	PUNCT
ecletica-1322	239	30	lawal	lawal	PROPN
ecletica-1322	239	31	,	,	PUNCT
ecletica-1322	239	32	s.	s.	PROPN
ecletica-1322	239	33	a.	a.	PROPN
ecletica-1322	239	34	;	;	PUNCT
ecletica-1322	239	35	olumade	olumade	PROPN
ecletica-1322	239	36	,	,	PUNCT
ecletica-1322	239	37	a.	a.	NOUN
ecletica-1322	239	38	a.	a.	NOUN
ecletica-1322	239	39	;	;	PUNCT
ecletica-1322	239	40	olopade	olopade	PROPN
ecletica-1322	239	41	,	,	PUNCT
ecletica-1322	239	42	e.	e.	PROPN
ecletica-1322	239	43	o.	o.	PROPN
ecletica-1322	239	44	;	;	PUNCT
ecletica-1322	239	45	oyedepo	oyedepo	NOUN
ecletica-1322	239	46	,	,	PUNCT
ecletica-1322	239	47	t.	t.	NOUN
ecletica-1322	239	48	a.	a.	NOUN
ecletica-1322	239	49	cardio	cardio	NOUN
ecletica-1322	239	50	-	-	PUNCT
ecletica-1322	239	51	protective	protective	ADJ
ecletica-1322	239	52	effect	effect	NOUN
ecletica-1322	239	53	of	of	ADP
ecletica-1322	239	54	hunteria	hunteria	PROPN
ecletica-1322	239	55	umbellata	umbellata	ADJ
ecletica-1322	239	56	seed	seed	NOUN
ecletica-1322	239	57	:	:	PUNCT
ecletica-1322	239	58	experimental	experimental	ADJ
ecletica-1322	239	59	and	and	CCONJ
ecletica-1322	239	60	in	in	ADP
ecletica-1322	239	61	-	-	PUNCT
ecletica-1322	239	62	silico	silico	NOUN
ecletica-1322	239	63	approaches	approach	NOUN
ecletica-1322	239	64	.	.	PUNCT
ecletica-1322	240	1	trop	trop	X
ecletica-1322	240	2	.	.	PUNCT
ecletica-1322	241	1	j.	j.	PROPN
ecletica-1322	241	2	nat	nat	PROPN
ecletica-1322	241	3	.	.	PUNCT
ecletica-1322	242	1	prod	prod	PROPN
ecletica-1322	242	2	.	.	PUNCT
ecletica-1322	243	1	res	re	NOUN
ecletica-1322	243	2	.	.	PROPN
ecletica-1322	243	3	2022	2022	NUM
ecletica-1322	243	4	,	,	PUNCT
ecletica-1322	243	5	6	6	NUM
ecletica-1322	243	6	(	(	PUNCT
ecletica-1322	243	7	1	1	NUM
ecletica-1322	243	8	)	)	PUNCT
ecletica-1322	243	9	,	,	PUNCT
ecletica-1322	243	10	87–94	87–94	PROPN
ecletica-1322	243	11	.	.	PROPN
ecletica-1322	243	12	https://doi.org/10.26538/tjnpr/v6i1.16	https://doi.org/10.26538/tjnpr/v6i1.16	PROPN
ecletica-1322	243	13	nisha	nisha	PROPN
ecletica-1322	243	14	,	,	PUNCT
ecletica-1322	243	15	c.	c.	PROPN
ecletica-1322	243	16	m.	m.	NOUN
ecletica-1322	243	17	;	;	PUNCT
ecletica-1322	243	18	kumar	kumar	PROPN
ecletica-1322	243	19	,	,	PUNCT
ecletica-1322	243	20	a.	a.	PROPN
ecletica-1322	243	21	;	;	PUNCT
ecletica-1322	243	22	nair	nair	NOUN
ecletica-1322	243	23	,	,	PUNCT
ecletica-1322	243	24	p.	p.	NOUN
ecletica-1322	243	25	;	;	PUNCT
ecletica-1322	243	26	gupta	gupta	PROPN
ecletica-1322	243	27	,	,	PUNCT
ecletica-1322	243	28	n.	n.	NOUN
ecletica-1322	243	29	;	;	PUNCT
ecletica-1322	243	30	silakari	silakari	PROPN
ecletica-1322	243	31	,	,	PUNCT
ecletica-1322	243	32	c.	c.	PROPN
ecletica-1322	243	33	;	;	PUNCT
ecletica-1322	243	34	tripathi	tripathi	PROPN
ecletica-1322	243	35	,	,	PUNCT
ecletica-1322	243	36	t.	t.	PROPN
ecletica-1322	243	37	;	;	PUNCT
ecletica-1322	243	38	kumar	kumar	PROPN
ecletica-1322	243	39	,	,	PUNCT
ecletica-1322	243	40	a.	a.	NOUN
ecletica-1322	243	41	molecular	molecular	ADJ
ecletica-1322	243	42	docking	docking	NOUN
ecletica-1322	243	43	and	and	CCONJ
ecletica-1322	243	44	in	in	ADP
ecletica-1322	243	45	silico	silico	NOUN
ecletica-1322	243	46	admet	admet	NOUN
ecletica-1322	243	47	study	study	NOUN
ecletica-1322	243	48	reveals	reveal	VERB
ecletica-1322	243	49	acylguanidine	acylguanidine	ADJ
ecletica-1322	243	50	7a	7a	NOUN
ecletica-1322	243	51	as	as	ADP
ecletica-1322	243	52	a	a	DET
ecletica-1322	243	53	potential	potential	ADJ
ecletica-1322	243	54	inhibitor	inhibitor	NOUN
ecletica-1322	243	55	of	of	ADP
ecletica-1322	243	56	𝛽-secretase	𝛽-secretase	NOUN
ecletica-1322	243	57	.	.	PUNCT
ecletica-1322	244	1	adv	adv	PROPN
ecletica-1322	244	2	.	.	PUNCT
ecletica-1322	244	3	bioinform	bioinform	PROPN
ecletica-1322	244	4	.	.	PUNCT
ecletica-1322	245	1	2016	2016	NUM
ecletica-1322	245	2	,	,	PUNCT
ecletica-1322	245	3	2016	2016	NUM
ecletica-1322	245	4	,	,	PUNCT
ecletica-1322	245	5	9258578	9258578	NUM
ecletica-1322	245	6	.	.	PUNCT
ecletica-1322	246	1	https://doi.org/10.1155/2016/9258578	https://doi.org/10.1155/2016/9258578	NOUN
ecletica-1322	246	2	oyebamiji	oyebamiji	NOUN
ecletica-1322	246	3	,	,	PUNCT
ecletica-1322	246	4	a.	a.	PROPN
ecletica-1322	246	5	k.	k.	PROPN
ecletica-1322	246	6	;	;	PUNCT
ecletica-1322	246	7	tolufashe	tolufashe	PROPN
ecletica-1322	246	8	,	,	PUNCT
ecletica-1322	246	9	g.	g.	PROPN
ecletica-1322	246	10	f.	f.	PROPN
ecletica-1322	246	11	;	;	PUNCT
ecletica-1322	246	12	oyawoye	oyawoye	PROPN
ecletica-1322	246	13	,	,	PUNCT
ecletica-1322	246	14	o.	o.	NOUN
ecletica-1322	246	15	m.	m.	NOUN
ecletica-1322	246	16	;	;	PUNCT
ecletica-1322	246	17	oyedepo	oyedepo	NOUN
ecletica-1322	246	18	,	,	PUNCT
ecletica-1322	246	19	t.	t.	NOUN
ecletica-1322	246	20	a.	a.	NOUN
ecletica-1322	246	21	;	;	PUNCT
ecletica-1322	246	22	semire	semire	NOUN
ecletica-1322	246	23	,	,	PUNCT
ecletica-1322	246	24	b.	b.	PROPN
ecletica-1322	246	25	biological	biological	ADJ
ecletica-1322	246	26	activity	activity	NOUN
ecletica-1322	246	27	of	of	ADP
ecletica-1322	246	28	selected	select	VERB
ecletica-1322	246	29	compounds	compound	NOUN
ecletica-1322	246	30	from	from	ADP
ecletica-1322	246	31	annona	annona	PROPN
ecletica-1322	246	32	muricata	muricata	NOUN
ecletica-1322	246	33	seed	seed	NOUN
ecletica-1322	246	34	as	as	ADP
ecletica-1322	246	35	antibreast	antibreast	NOUN
ecletica-1322	246	36	cancer	cancer	NOUN
ecletica-1322	246	37	agents	agent	NOUN
ecletica-1322	246	38	:	:	PUNCT
ecletica-1322	246	39	theoretical	theoretical	ADJ
ecletica-1322	246	40	study	study	NOUN
ecletica-1322	246	41	.	.	PUNCT
ecletica-1322	247	1	j.	j.	PROPN
ecletica-1322	247	2	chem	chem	PROPN
ecletica-1322	247	3	.	.	PUNCT
ecletica-1322	248	1	2020	2020	NUM
ecletica-1322	248	2	,	,	PUNCT
ecletica-1322	248	3	2020	2020	NUM
ecletica-1322	248	4	,	,	PUNCT
ecletica-1322	248	5	6735232	6735232	NUM
ecletica-1322	248	6	.	.	PUNCT
ecletica-1322	249	1	https://doi.org/10.1155/2020/6735232	https://doi.org/10.1155/2020/6735232	PROPN
ecletica-1322	249	2	oyebamiji	oyebamiji	PROPN
ecletica-1322	249	3	,	,	PUNCT
ecletica-1322	249	4	a.	a.	PROPN
ecletica-1322	249	5	k.	k.	PROPN
ecletica-1322	249	6	;	;	PUNCT
ecletica-1322	249	7	fadare	fadare	VERB
ecletica-1322	249	8	,	,	PUNCT
ecletica-1322	249	9	o.	o.	NOUN
ecletica-1322	249	10	a.	a.	NOUN
ecletica-1322	249	11	;	;	PUNCT
ecletica-1322	250	1	akintelu	akintelu	ADV
ecletica-1322	250	2	,	,	PUNCT
ecletica-1322	250	3	s.	s.	PROPN
ecletica-1322	250	4	a.	a.	PROPN
ecletica-1322	250	5	;	;	PUNCT
ecletica-1322	250	6	semire	semire	NOUN
ecletica-1322	250	7	,	,	PUNCT
ecletica-1322	250	8	b.	b.	PROPN
ecletica-1322	250	9	biological	biological	ADJ
ecletica-1322	250	10	studies	study	NOUN
ecletica-1322	250	11	on	on	ADP
ecletica-1322	250	12	anthra[1,9	anthra[1,9	PROPN
ecletica-1322	250	13	-	-	PUNCT
ecletica-1322	250	14	cd]pyrazol-6(2d)-one	cd]pyrazol-6(2d)-one	NUM
ecletica-1322	250	15	analogues	analogue	NOUN
ecletica-1322	250	16	as	as	ADP
ecletica-1322	250	17	anti	anti	ADJ
ecletica-1322	250	18	-	-	ADJ
ecletica-1322	250	19	vascular	vascular	ADJ
ecletica-1322	250	20	endothelial	endothelial	ADJ
ecletica-1322	250	21	growth	growth	NOUN
ecletica-1322	250	22	factor	factor	NOUN
ecletica-1322	250	23	via	via	ADP
ecletica-1322	250	24	in	in	ADP
ecletica-1322	250	25	silico	silico	NOUN
ecletica-1322	250	26	mechanisms	mechanism	NOUN
ecletica-1322	250	27	.	.	PUNCT
ecletica-1322	251	1	chemistry	chemistry	PROPN
ecletica-1322	251	2	africa	africa	PROPN
ecletica-1322	251	3	.	.	PUNCT
ecletica-1322	252	1	2021a	2021a	NUM
ecletica-1322	252	2	,	,	PUNCT
ecletica-1322	252	3	4	4	NUM
ecletica-1322	252	4	(	(	PUNCT
ecletica-1322	252	5	4	4	NUM
ecletica-1322	252	6	)	)	PUNCT
ecletica-1322	252	7	,	,	PUNCT
ecletica-1322	252	8	955–963	955–963	NUM
ecletica-1322	252	9	.	.	PUNCT
ecletica-1322	253	1	https://doi.org/10.1007/s42250-021-00276-2	https://doi.org/10.1007/s42250-021-00276-2	NOUN
ecletica-1322	253	2	oyebamiji	oyebamiji	NOUN
ecletica-1322	253	3	,	,	PUNCT
ecletica-1322	253	4	a.	a.	PROPN
ecletica-1322	253	5	k.	k.	PROPN
ecletica-1322	253	6	;	;	PUNCT
ecletica-1322	253	7	josiah	josiah	PROPN
ecletica-1322	253	8	o.	o.	PROPN
ecletica-1322	253	9	m.	m.	PROPN
ecletica-1322	253	10	;	;	PUNCT
ecletica-1322	253	11	akintelu	akintelu	ADV
ecletica-1322	253	12	,	,	PUNCT
ecletica-1322	253	13	s.	s.	PROPN
ecletica-1322	253	14	a.	a.	PROPN
ecletica-1322	253	15	;	;	PUNCT
ecletica-1322	253	16	adeoye	adeoye	PROPN
ecletica-1322	253	17	,	,	PUNCT
ecletica-1322	253	18	m.	m.	PROPN
ecletica-1322	253	19	d.	d.	PROPN
ecletica-1322	253	20	;	;	PUNCT
ecletica-1322	253	21	sabitu	sabitu	PROPN
ecletica-1322	253	22	,	,	PUNCT
ecletica-1322	253	23	b.	b.	PROPN
ecletica-1322	253	24	o.	o.	PROPN
ecletica-1322	253	25	;	;	PUNCT
ecletica-1322	253	26	latona	latona	PROPN
ecletica-1322	253	27	,	,	PUNCT
ecletica-1322	253	28	d.	d.	PROPN
ecletica-1322	253	29	f.	f.	PROPN
ecletica-1322	253	30	;	;	PUNCT
ecletica-1322	253	31	esan	esan	PROPN
ecletica-1322	253	32	,	,	PUNCT
ecletica-1322	253	33	a.	a.	NOUN
ecletica-1322	253	34	o.	o.	PROPN
ecletica-1322	253	35	;	;	PUNCT
ecletica-1322	253	36	soetan	soetan	PROPN
ecletica-1322	253	37	,	,	PUNCT
ecletica-1322	253	38	e.	e.	PROPN
ecletica-1322	253	39	a.	a.	PROPN
ecletica-1322	253	40	;	;	PUNCT
ecletica-1322	253	41	semire	semire	NOUN
ecletica-1322	253	42	,	,	PUNCT
ecletica-1322	253	43	b.	b.	PROPN
ecletica-1322	253	44	dataset	dataset	PROPN
ecletica-1322	253	45	on	on	ADP
ecletica-1322	253	46	insightful	insightful	ADJ
ecletica-1322	253	47	bio	bio	NOUN
ecletica-1322	253	48	-	-	NOUN
ecletica-1322	253	49	evaluation	evaluation	NOUN
ecletica-1322	253	50	of	of	ADP
ecletica-1322	253	51	2(quinoline-4	2(quinoline-4	NOUN
ecletica-1322	253	52	-	-	SYM
ecletica-1322	253	53	yloxy)acetamide	yloxy)acetamide	NOUN
ecletica-1322	253	54	analogues	analogue	NOUN
ecletica-1322	253	55	as	as	ADP
ecletica-1322	253	56	potential	potential	ADJ
ecletica-1322	253	57	antimycobacterium	antimycobacterium	NOUN
ecletica-1322	253	58	tuberculosis	tuberculosis	NOUN
ecletica-1322	253	59	catalase	catalase	NOUN
ecletica-1322	253	60	-	-	PUNCT
ecletica-1322	253	61	peroxidase	peroxidase	NOUN
ecletica-1322	253	62	agents	agent	NOUN
ecletica-1322	253	63	via	via	ADP
ecletica-1322	253	64	in	in	ADP
ecletica-1322	253	65	silico	silico	NOUN
ecletica-1322	253	66	mechanisms	mechanism	NOUN
ecletica-1322	253	67	.	.	PUNCT
ecletica-1322	254	1	data	data	PROPN
ecletica-1322	254	2	br	br	PROPN
ecletica-1322	254	3	.	.	PROPN
ecletica-1322	254	4	2021b	2021b	NUM
ecletica-1322	254	5	,	,	PUNCT
ecletica-1322	254	6	38	38	NUM
ecletica-1322	254	7	,	,	PUNCT
ecletica-1322	254	8	107441	107441	NUM
ecletica-1322	254	9	.	.	PUNCT
ecletica-1322	255	1	https://doi.org/10.1016/j.dib.2021.107441	https://doi.org/10.1016/j.dib.2021.107441	NOUN
ecletica-1322	255	2	oyebamiji	oyebamiji	NOUN
ecletica-1322	255	3	,	,	PUNCT
ecletica-1322	255	4	a.	a.	PROPN
ecletica-1322	255	5	k.	k.	PROPN
ecletica-1322	255	6	;	;	PUNCT
ecletica-1322	255	7	soetan	soetan	PROPN
ecletica-1322	255	8	,	,	PUNCT
ecletica-1322	255	9	e.	e.	PROPN
ecletica-1322	255	10	a.	a.	PROPN
ecletica-1322	255	11	;	;	PUNCT
ecletica-1322	255	12	akintelu	akintelu	PROPN
ecletica-1322	255	13	,	,	PUNCT
ecletica-1322	255	14	s.	s.	PROPN
ecletica-1322	255	15	a.	a.	PROPN
ecletica-1322	255	16	;	;	PUNCT
ecletica-1322	255	17	ayeleso	ayeleso	NOUN
ecletica-1322	255	18	,	,	PUNCT
ecletica-1322	255	19	a.	a.	NOUN
ecletica-1322	255	20	o.	o.	PROPN
ecletica-1322	255	21	;	;	PUNCT
ecletica-1322	255	22	mukwevho	mukwevho	PROPN
ecletica-1322	255	23	,	,	PUNCT
ecletica-1322	255	24	e.	e.	PROPN
ecletica-1322	255	25	alpha	alpha	PROPN
ecletica-1322	255	26	-	-	PUNCT
ecletica-1322	255	27	glucosidase	glucosidase	ADJ
ecletica-1322	255	28	activity	activity	NOUN
ecletica-1322	255	29	of	of	ADP
ecletica-1322	255	30	phytochemicals	phytochemical	NOUN
ecletica-1322	255	31	from	from	ADP
ecletica-1322	255	32	phyllanthus	phyllanthus	PROPN
ecletica-1322	255	33	amarus	amarus	NOUN
ecletica-1322	255	34	leaves	leave	NOUN
ecletica-1322	255	35	via	via	ADP
ecletica-1322	255	36	in	in	ADP
ecletica-1322	255	37	-	-	PUNCT
ecletica-1322	255	38	silico	silico	NOUN
ecletica-1322	255	39	approaches	approach	NOUN
ecletica-1322	255	40	.	.	PUNCT
ecletica-1322	256	1	pharmacological	pharmacological	ADJ
ecletica-1322	256	2	research	research	NOUN
ecletica-1322	256	3	modern	modern	ADJ
ecletica-1322	256	4	chinese	chinese	ADJ
ecletica-1322	256	5	medicine	medicine	NOUN
ecletica-1322	256	6	.	.	PUNCT
ecletica-1322	257	1	2022	2022	NUM
ecletica-1322	257	2	,	,	PUNCT
ecletica-1322	257	3	2	2	NUM
ecletica-1322	257	4	,	,	PUNCT
ecletica-1322	257	5	00054	00054	NUM
ecletica-1322	257	6	.	.	PUNCT
ecletica-1322	258	1	https://doi.org/10.1016/j.prmcm.2022.100054	https://doi.org/10.1016/j.prmcm.2022.100054	ADJ
ecletica-1322	258	2	oyewole	oyewole	NOUN
ecletica-1322	258	3	,	,	PUNCT
ecletica-1322	258	4	r.	r.	PROPN
ecletica-1322	258	5	o.	o.	PROPN
ecletica-1322	258	6	;	;	PUNCT
ecletica-1322	258	7	oyebamiji	oyebamiji	PROPN
ecletica-1322	258	8	,	,	PUNCT
ecletica-1322	258	9	a.	a.	PROPN
ecletica-1322	258	10	k.	k.	PROPN
ecletica-1322	258	11	;	;	PUNCT
ecletica-1322	258	12	semire	semire	PROPN
ecletica-1322	258	13	,	,	PUNCT
ecletica-1322	258	14	b.	b.	PROPN
ecletica-1322	258	15	theoretical	theoretical	ADJ
ecletica-1322	258	16	calculations	calculation	NOUN
ecletica-1322	258	17	of	of	ADP
ecletica-1322	258	18	molecular	molecular	ADJ
ecletica-1322	258	19	descriptors	descriptor	NOUN
ecletica-1322	258	20	for	for	ADP
ecletica-1322	258	21	anticancer	anticancer	NOUN
ecletica-1322	258	22	activities	activity	NOUN
ecletica-1322	258	23	of	of	ADP
ecletica-1322	258	24	1	1	NUM
ecletica-1322	258	25	,	,	PUNCT
ecletica-1322	258	26	2	2	NUM
ecletica-1322	258	27	,	,	PUNCT
ecletica-1322	258	28	3	3	NUM
ecletica-1322	258	29	-	-	PUNCT
ecletica-1322	258	30	triazole	triazole	ADJ
ecletica-1322	258	31	-	-	PUNCT
ecletica-1322	258	32	pyrimidine	pyrimidine	NOUN
ecletica-1322	258	33	derivatives	derivative	NOUN
ecletica-1322	258	34	against	against	ADP
ecletica-1322	258	35	gastric	gastric	ADJ
ecletica-1322	258	36	cancer	cancer	NOUN
ecletica-1322	258	37	cell	cell	NOUN
ecletica-1322	258	38	line	line	NOUN
ecletica-1322	258	39	(	(	PUNCT
ecletica-1322	258	40	mgc-803	mgc-803	NOUN
ecletica-1322	258	41	):	):	PUNCT
ecletica-1322	258	42	dft	dft	PROPN
ecletica-1322	258	43	,	,	PUNCT
ecletica-1322	258	44	qsar	qsar	NOUN
ecletica-1322	258	45	and	and	CCONJ
ecletica-1322	258	46	docking	docking	NOUN
ecletica-1322	258	47	approaches	approach	NOUN
ecletica-1322	258	48	.	.	PUNCT
ecletica-1322	259	1	heliyon	heliyon	NOUN
ecletica-1322	259	2	.	.	PUNCT
ecletica-1322	260	1	2020	2020	NUM
ecletica-1322	260	2	,	,	PUNCT
ecletica-1322	260	3	6	6	NUM
ecletica-1322	260	4	(	(	PUNCT
ecletica-1322	260	5	5	5	NUM
ecletica-1322	260	6	)	)	PUNCT
ecletica-1322	260	7	,	,	PUNCT
ecletica-1322	260	8	e03926	e03926	PROPN
ecletica-1322	260	9	.	.	PUNCT
ecletica-1322	261	1	https://doi.org/10.1016/j.heliyon.2020.e03926	https://doi.org/10.1016/j.heliyon.2020.e03926	NOUN
ecletica-1322	261	2	palermo	palermo	PROPN
ecletica-1322	261	3	,	,	PUNCT
ecletica-1322	261	4	g.	g.	PROPN
ecletica-1322	261	5	;	;	PUNCT
ecletica-1322	261	6	vivo	vivo	NOUN
ecletica-1322	261	7	,	,	PUNCT
ecletica-1322	261	8	m.	m.	NOUN
ecletica-1322	261	9	computational	computational	ADJ
ecletica-1322	261	10	chemistry	chemistry	NOUN
ecletica-1322	261	11	for	for	ADP
ecletica-1322	261	12	drug	drug	NOUN
ecletica-1322	261	13	discovery	discovery	NOUN
ecletica-1322	261	14	.	.	PUNCT
ecletica-1322	262	1	in	in	ADP
ecletica-1322	262	2	encyclopedia	encyclopedia	NOUN
ecletica-1322	262	3	of	of	ADP
ecletica-1322	262	4	nanotechnology	nanotechnology	PROPN
ecletica-1322	262	5	.	.	PUNCT
ecletica-1322	263	1	springer	springer	NOUN
ecletica-1322	263	2	science	science	PROPN
ecletica-1322	263	3	,	,	PUNCT
ecletica-1322	263	4	2015	2015	NUM
ecletica-1322	263	5	;	;	PUNCT
ecletica-1322	263	6	pp	pp	ADP
ecletica-1322	263	7	1–15	1–15	NUM
ecletica-1322	263	8	.	.	PUNCT
ecletica-1322	264	1	https://doi.org/10.1007/978-94-0076178-0_100975-1	https://doi.org/10.1007/978-94-0076178-0_100975-1	PROPN
ecletica-1322	264	2	patil	patil	PROPN
ecletica-1322	264	3	,	,	PUNCT
ecletica-1322	264	4	p.	p.	PROPN
ecletica-1322	264	5	s.	s.	PROPN
ecletica-1322	264	6	drug	drug	PROPN
ecletica-1322	264	7	discovery	discovery	PROPN
ecletica-1322	264	8	and	and	CCONJ
ecletica-1322	264	9	admet	admet	PROPN
ecletica-1322	264	10	process	process	NOUN
ecletica-1322	264	11	:	:	PUNCT
ecletica-1322	264	12	a	a	DET
ecletica-1322	264	13	review	review	NOUN
ecletica-1322	264	14	.	.	PUNCT
ecletica-1322	265	1	int	int	NOUN
ecletica-1322	265	2	.	.	PUNCT
ecletica-1322	266	1	j.	j.	PROPN
ecletica-1322	266	2	adv	adv	PROPN
ecletica-1322	266	3	.	.	PUNCT
ecletica-1322	267	1	res	re	NOUN
ecletica-1322	267	2	.	.	PUNCT
ecletica-1322	268	1	biol	biol	PROPN
ecletica-1322	268	2	.	.	PUNCT
ecletica-1322	269	1	sci	sci	PROPN
ecletica-1322	269	2	.	.	PROPN
ecletica-1322	269	3	2016	2016	NUM
ecletica-1322	269	4	,	,	PUNCT
ecletica-1322	269	5	3	3	NUM
ecletica-1322	269	6	(	(	PUNCT
ecletica-1322	269	7	7	7	NUM
ecletica-1322	269	8	)	)	PUNCT
ecletica-1322	269	9	,	,	PUNCT
ecletica-1322	269	10	181–192	181–192	NUM
ecletica-1322	269	11	.	.	PUNCT
ecletica-1322	269	12	http://s-oi.org/1.15/ijarbs-2016-3-7-26	http://s-oi.org/1.15/ijarbs-2016-3-7-26	PROPN
ecletica-1322	269	13	raj	raj	PROPN
ecletica-1322	269	14	,	,	PUNCT
ecletica-1322	269	15	u.	u.	PROPN
ecletica-1322	269	16	;	;	PUNCT
ecletica-1322	269	17	kumar	kumar	PROPN
ecletica-1322	269	18	,	,	PUNCT
ecletica-1322	269	19	h.	h.	PROPN
ecletica-1322	269	20	;	;	PUNCT
ecletica-1322	269	21	gupta	gupta	PROPN
ecletica-1322	269	22	,	,	PUNCT
ecletica-1322	269	23	s.	s.	PROPN
ecletica-1322	269	24	;	;	PUNCT
ecletica-1322	269	25	varadwaj	varadwaj	NOUN
ecletica-1322	269	26	,	,	PUNCT
ecletica-1322	269	27	p.	p.	PROPN
ecletica-1322	269	28	k.	k.	PROPN
ecletica-1322	270	1	novel	novel	PROPN
ecletica-1322	270	2	dot1l	dot1l	PROPN
ecletica-1322	270	3	receptor	receptor	NOUN
ecletica-1322	270	4	natural	natural	ADJ
ecletica-1322	270	5	inhibitors	inhibitor	NOUN
ecletica-1322	270	6	involved	involve	VERB
ecletica-1322	270	7	in	in	ADP
ecletica-1322	270	8	mixed	mixed	ADJ
ecletica-1322	270	9	lineage	lineage	NOUN
ecletica-1322	270	10	leukemia	leukemia	NOUN
ecletica-1322	270	11	:	:	PUNCT
ecletica-1322	270	12	a	a	DET
ecletica-1322	270	13	virtual	virtual	ADJ
ecletica-1322	270	14	screening	screening	NOUN
ecletica-1322	270	15	,	,	PUNCT
ecletica-1322	270	16	molecular	molecular	ADJ
ecletica-1322	270	17	docking	docking	NOUN
ecletica-1322	270	18	and	and	CCONJ
ecletica-1322	270	19	dynamics	dynamic	NOUN
ecletica-1322	270	20	simulation	simulation	NOUN
ecletica-1322	270	21	study	study	PROPN
ecletica-1322	270	22	.	.	PUNCT
ecletica-1322	271	1	asian	asian	PROPN
ecletica-1322	271	2	pac	pac	PROPN
ecletica-1322	271	3	.	.	PUNCT
ecletica-1322	272	1	j.	j.	PROPN
ecletica-1322	272	2	cancer	cancer	PROPN
ecletica-1322	272	3	prev	prev	PROPN
ecletica-1322	272	4	.	.	PROPN
ecletica-1322	272	5	2015	2015	NUM
ecletica-1322	272	6	,	,	PUNCT
ecletica-1322	272	7	16	16	NUM
ecletica-1322	272	8	(	(	PUNCT
ecletica-1322	272	9	9	9	NUM
ecletica-1322	272	10	)	)	PUNCT
ecletica-1322	272	11	,	,	PUNCT
ecletica-1322	272	12	3817–3825	3817–3825	NUM
ecletica-1322	272	13	.	.	PUNCT
ecletica-1322	273	1	https://doi.org/10.7314/apjcp.2015.16.9.3817	https://doi.org/10.7314/apjcp.2015.16.9.3817	PROPN
ecletica-1322	273	2	roche	roche	PROPN
ecletica-1322	273	3	,	,	PUNCT
ecletica-1322	273	4	d.	d.	PROPN
ecletica-1322	273	5	b.	b.	PROPN
ecletica-1322	273	6	;	;	PUNCT
ecletica-1322	273	7	brackenridge	brackenridge	PROPN
ecletica-1322	273	8	,	,	PUNCT
ecletica-1322	273	9	d.	d.	PROPN
ecletica-1322	273	10	a.	a.	PROPN
ecletica-1322	273	11	;	;	PUNCT
ecletica-1322	273	12	guffin	guffin	NOUN
ecletica-1322	273	13	,	,	PUNCT
ecletica-1322	273	14	l.	l.	PROPN
ecletica-1322	273	15	j.	j.	PROPN
ecletica-1322	273	16	proteins	proteins	PROPN
ecletica-1322	273	17	and	and	CCONJ
ecletica-1322	273	18	their	their	PRON
ecletica-1322	273	19	interacting	interact	VERB
ecletica-1322	273	20	partners	partner	NOUN
ecletica-1322	273	21	:	:	PUNCT
ecletica-1322	273	22	an	an	DET
ecletica-1322	273	23	introduction	introduction	NOUN
ecletica-1322	273	24	to	to	ADP
ecletica-1322	273	25	protein	protein	NOUN
ecletica-1322	273	26	-	-	PUNCT
ecletica-1322	273	27	ligand	ligand	ADJ
ecletica-1322	273	28	binding	bind	VERB
ecletica-1322	273	29	site	site	NOUN
ecletica-1322	273	30	prediction	prediction	NOUN
ecletica-1322	273	31	methods	method	NOUN
ecletica-1322	273	32	.	.	PUNCT
ecletica-1322	274	1	int	int	NOUN
ecletica-1322	274	2	.	.	PUNCT
ecletica-1322	275	1	j.	j.	PROPN
ecletica-1322	275	2	mol	mol	PROPN
ecletica-1322	275	3	.	.	PUNCT
ecletica-1322	276	1	sci	sci	PROPN
ecletica-1322	276	2	.	.	PROPN
ecletica-1322	276	3	2015	2015	NUM
ecletica-1322	276	4	,	,	PUNCT
ecletica-1322	276	5	16	16	NUM
ecletica-1322	276	6	(	(	PUNCT
ecletica-1322	276	7	12	12	NUM
ecletica-1322	276	8	)	)	PUNCT
ecletica-1322	276	9	,	,	PUNCT
ecletica-1322	276	10	29829–29842	29829–29842	NUM
ecletica-1322	276	11	.	.	PUNCT
ecletica-1322	277	1	https://doi.org/10.3390/ijms161226202	https://doi.org/10.3390/ijms161226202	PROPN
ecletica-1322	277	2	semire	semire	PROPN
ecletica-1322	277	3	,	,	PUNCT
ecletica-1322	277	4	b.	b.	PROPN
ecletica-1322	277	5	;	;	PUNCT
ecletica-1322	277	6	mutiu	mutiu	NOUN
ecletica-1322	277	7	,	,	PUNCT
ecletica-1322	277	8	o.	o.	PROPN
ecletica-1322	277	9	a.	a.	PROPN
ecletica-1322	277	10	;	;	PUNCT
ecletica-1322	277	11	oyebamiji	oyebamiji	NOUN
ecletica-1322	277	12	,	,	PUNCT
ecletica-1322	277	13	a.	a.	PROPN
ecletica-1322	277	14	k.	k.	PROPN
ecletica-1322	277	15	dft	dft	PROPN
ecletica-1322	277	16	and	and	CCONJ
ecletica-1322	277	17	ab	ab	PROPN
ecletica-1322	277	18	initio	initio	NOUN
ecletica-1322	277	19	methods	method	NOUN
ecletica-1322	277	20	on	on	ADP
ecletica-1322	277	21	nmr	nmr	NOUN
ecletica-1322	277	22	,	,	PUNCT
ecletica-1322	277	23	ir	ir	NOUN
ecletica-1322	277	24	and	and	CCONJ
ecletica-1322	277	25	reactivity	reactivity	NOUN
ecletica-1322	277	26	indices	index	NOUN
ecletica-1322	277	27	of	of	ADP
ecletica-1322	277	28	indol-3carboxylate	indol-3carboxylate	NOUN
ecletica-1322	277	29	and	and	CCONJ
ecletica-1322	277	30	indazole-3	indazole-3	NUM
ecletica-1322	277	31	-	-	PUNCT
ecletica-1322	277	32	carboxylate	carboxylate	NOUN
ecletica-1322	277	33	derivatives	derivative	NOUN
ecletica-1322	277	34	of	of	ADP
ecletica-1322	277	35	cannabinoids	cannabinoid	NOUN
ecletica-1322	277	36	:	:	PUNCT
ecletica-1322	277	37	comparative	comparative	ADJ
ecletica-1322	277	38	study	study	NOUN
ecletica-1322	277	39	.	.	PUNCT
ecletica-1322	278	1	j.	j.	PROPN
ecletica-1322	278	2	phys	phys	PROPN
ecletica-1322	278	3	.	.	PUNCT
ecletica-1322	279	1	theor	theor	PROPN
ecletica-1322	279	2	.	.	PUNCT
ecletica-1322	279	3	chem	chem	PROPN
ecletica-1322	279	4	.	.	PUNCT
ecletica-1322	280	1	iau	iau	PROPN
ecletica-1322	280	2	,	,	PUNCT
ecletica-1322	280	3	iran	iran	PROPN
ecletica-1322	280	4	.	.	PUNCT
ecletica-1322	281	1	2017	2017	NUM
ecletica-1322	281	2	,	,	PUNCT
ecletica-1322	281	3	13	13	NUM
ecletica-1322	281	4	(	(	PUNCT
ecletica-1322	281	5	4	4	NUM
ecletica-1322	281	6	)	)	PUNCT
ecletica-1322	281	7	,	,	PUNCT
ecletica-1322	281	8	353–377	353–377	NUM
ecletica-1322	281	9	.	.	PUNCT
ecletica-1322	281	10	stefaniu	stefaniu	NOUN
ecletica-1322	281	11	a.	a.	PROPN
ecletica-1322	281	12	;	;	PUNCT
ecletica-1322	281	13	pintilie	pintilie	NOUN
ecletica-1322	281	14	,	,	PUNCT
ecletica-1322	281	15	l.	l.	PROPN
ecletica-1322	281	16	molecular	molecular	ADJ
ecletica-1322	281	17	descriptors	descriptor	NOUN
ecletica-1322	281	18	and	and	CCONJ
ecletica-1322	281	19	properties	property	NOUN
ecletica-1322	281	20	of	of	ADP
ecletica-1322	281	21	organic	organic	ADJ
ecletica-1322	281	22	molecules	molecule	NOUN
ecletica-1322	281	23	.	.	PUNCT
ecletica-1322	282	1	in	in	ADP
ecletica-1322	282	2	symmetry	symmetry	NOUN
ecletica-1322	282	3	(	(	PUNCT
ecletica-1322	282	4	group	group	NOUN
ecletica-1322	282	5	theory	theory	NOUN
ecletica-1322	282	6	)	)	PUNCT
ecletica-1322	282	7	and	and	CCONJ
ecletica-1322	282	8	mathematical	mathematical	ADJ
ecletica-1322	282	9	treatment	treatment	NOUN
ecletica-1322	282	10	in	in	ADP
ecletica-1322	282	11	chemistry	chemistry	NOUN
ecletica-1322	282	12	.	.	PUNCT
ecletica-1322	283	1	intechopen	intechopen	ADJ
ecletica-1322	283	2	,	,	PUNCT
ecletica-1322	283	3	2018	2018	NUM
ecletica-1322	283	4	;	;	PUNCT
ecletica-1322	283	5	pp	pp	ADP
ecletica-1322	284	1	161–177	161–177	NUM
ecletica-1322	284	2	.	.	PUNCT
ecletica-1322	285	1	https://doi.org/10.5772/intechopen.72840	https://doi.org/10.5772/intechopen.72840	PROPN
ecletica-1322	285	2	venkatesh	venkatesh	PROPN
ecletica-1322	285	3	,	,	PUNCT
ecletica-1322	285	4	k.	k.	PROPN
ecletica-1322	285	5	;	;	PUNCT
ecletica-1322	285	6	aravinda	aravinda	PROPN
ecletica-1322	285	7	,	,	PUNCT
ecletica-1322	285	8	p.	p.	NOUN
ecletica-1322	285	9	application	application	NOUN
ecletica-1322	285	10	of	of	ADP
ecletica-1322	285	11	molecular	molecular	ADJ
ecletica-1322	285	12	descriptors	descriptor	NOUN
ecletica-1322	285	13	in	in	ADP
ecletica-1322	285	14	modern	modern	ADJ
ecletica-1322	285	15	computational	computational	ADJ
ecletica-1322	285	16	drug	drug	NOUN
ecletica-1322	285	17	design	design	NOUN
ecletica-1322	285	18	-	-	PUNCT
ecletica-1322	285	19	an	an	DET
ecletica-1322	285	20	overview	overview	NOUN
ecletica-1322	285	21	.	.	PUNCT
ecletica-1322	286	1	research	research	NOUN
ecletica-1322	286	2	j.	j.	PROPN
ecletica-1322	286	3	pharm	pharm	PROPN
ecletica-1322	286	4	.	.	PUNCT
ecletica-1322	287	1	tech	tech	NOUN
ecletica-1322	287	2	.	.	PUNCT
ecletica-1322	288	1	2017	2017	NUM
ecletica-1322	288	2	,	,	PUNCT
ecletica-1322	288	3	10	10	NUM
ecletica-1322	288	4	(	(	PUNCT
ecletica-1322	288	5	9	9	NUM
ecletica-1322	288	6	)	)	PUNCT
ecletica-1322	288	7	,	,	PUNCT
ecletica-1322	288	8	3237–3241	3237–3241	NUM
ecletica-1322	288	9	.	.	PUNCT
ecletica-1322	288	10	https://doi.org/10.5958/0974-360x.2017.00574.1	https://doi.org/10.5958/0974-360x.2017.00574.1	PROPN
ecletica-1322	288	11	wu	wu	PROPN
ecletica-1322	288	12	,	,	PUNCT
ecletica-1322	288	13	c.-y	c.-y	NOUN
ecletica-1322	288	14	.	.	PUNCT
ecletica-1322	288	15	;	;	PUNCT
ecletica-1322	289	1	kuo	kuo	PROPN
ecletica-1322	289	2	,	,	PUNCT
ecletica-1322	289	3	k.	k.	PROPN
ecletica-1322	289	4	n.	n.	PROPN
ecletica-1322	289	5	;	;	PUNCT
ecletica-1322	289	6	wu	wu	PROPN
ecletica-1322	289	7	,	,	PUNCT
ecletica-1322	289	8	m.-s	m.-s	PROPN
ecletica-1322	289	9	.	.	PUNCT
ecletica-1322	289	10	;	;	PUNCT
ecletica-1322	289	11	chen	chen	PROPN
ecletica-1322	289	12	,	,	PUNCT
ecletica-1322	289	13	y.-j	y.-j	PROPN
ecletica-1322	289	14	.	.	PROPN
ecletica-1322	289	15	;	;	PUNCT
ecletica-1322	289	16	wang	wang	PROPN
ecletica-1322	289	17	,	,	PUNCT
ecletica-1322	289	18	c.-b	c.-b	PROPN
ecletica-1322	289	19	.	.	PROPN
ecletica-1322	289	20	;	;	PUNCT
ecletica-1322	289	21	lin	lin	PROPN
ecletica-1322	289	22	,	,	PUNCT
ecletica-1322	289	23	j.-t	j.-t	PROPN
ecletica-1322	289	24	.	.	PUNCT
ecletica-1322	290	1	early	early	ADJ
ecletica-1322	290	2	helicobacter	helicobacter	NOUN
ecletica-1322	290	3	pylori	pylori	NOUN
ecletica-1322	290	4	decreases	decrease	VERB
ecletica-1322	290	5	patients	patient	NOUN
ecletica-1322	290	6	with	with	ADP
ecletica-1322	290	7	peptic	peptic	ADJ
ecletica-1322	290	8	ulcer	ulcer	NOUN
ecletica-1322	290	9	diseases	disease	NOUN
ecletica-1322	290	10	.	.	PUNCT
ecletica-1322	291	1	gastroenterology	gastroenterology	NOUN
ecletica-1322	291	2	.	.	PUNCT
ecletica-1322	292	1	2009	2009	NUM
ecletica-1322	292	2	,	,	PUNCT
ecletica-1322	292	3	137	137	NUM
ecletica-1322	292	4	(	(	PUNCT
ecletica-1322	292	5	5	5	NUM
ecletica-1322	292	6	)	)	PUNCT
ecletica-1322	292	7	,	,	PUNCT
ecletica-1322	292	8	16411648	16411648	NUM
ecletica-1322	292	9	.	.	PUNCT
ecletica-1322	293	1	https://doi.org/10.1053/j.gastro.2009.07.060	https://doi.org/10.1053/j.gastro.2009.07.060	NOUN
ecletica-1322	293	2	https://revista.iq.unesp.br/index.php/ecletica	https://revista.iq.unesp.br/index.php/ecletica	PROPN
ecletica-1322	293	3	https://doi.org/10.26850/1678-4618eqj.v47.4.2022.p27-36	https://doi.org/10.26850/1678-4618eqj.v47.4.2022.p27-36	NOUN
ecletica-1322	293	4	https://doi.org/10.3762/bjoc.8.4	https://doi.org/10.3762/bjoc.8.4	X
ecletica-1322	293	5	https://doi.org/10.3762/bjoc.8.4	https://doi.org/10.3762/bjoc.8.4	X
ecletica-1322	293	6	https://doi.org/10.3762/bjoc.8.4	https://doi.org/10.3762/bjoc.8.4	X
ecletica-1322	294	1	https://doi.org/10.1016/s0169-409x(00)00129-0	https://doi.org/10.1016/s0169-409x(00)00129-0	PROPN
ecletica-1322	294	2	https://doi.org/10.1016/s0169-409x(00)00129-0	https://doi.org/10.1016/s0169-409x(00)00129-0	PROPN
ecletica-1322	295	1	https://doi.org/10.1016/s0169-409x(00)00129-0	https://doi.org/10.1016/s0169-409x(00)00129-0	PROPN
ecletica-1322	296	1	https://doi.org/10.1016/s0169-409x(00)00129-0	https://doi.org/10.1016/s0169-409x(00)00129-0	PROPN
ecletica-1322	296	2	https://doi.org/10.1016/s0169-409x(00)00129-0	https://doi.org/10.1016/s0169-409x(00)00129-0	PROPN
ecletica-1322	296	3	https://doi.org/10.1016/s0169-409x(00)00129-0	https://doi.org/10.1016/s0169-409x(00)00129-0	ADJ
ecletica-1322	296	4	https://doi.org/10.1111/febs.12020	https://doi.org/10.1111/febs.12020	ADV
ecletica-1322	296	5	https://doi.org/10.1111/febs.12020	https://doi.org/10.1111/febs.12020	ADV
ecletica-1322	296	6	https://doi.org/10.1111/febs.12020	https://doi.org/10.1111/febs.12020	ADV
ecletica-1322	296	7	https://doi.org/10.1111/febs.12020	https://doi.org/10.1111/febs.12020	ADV
ecletica-1322	296	8	https://doi.org/10.1111/febs.12020	https://doi.org/10.1111/febs.12020	X
ecletica-1322	296	9	https://doi.org/10.1016/j.drudis.2016.08.009	https://doi.org/10.1016/j.drudis.2016.08.009	PROPN
ecletica-1322	296	10	https://doi.org/10.1016/j.drudis.2016.08.009	https://doi.org/10.1016/j.drudis.2016.08.009	PROPN
ecletica-1322	296	11	https://doi.org/10.1016/j.drudis.2016.08.009	https://doi.org/10.1016/j.drudis.2016.08.009	PROPN
ecletica-1322	296	12	https://doi.org/10.1016/j.drudis.2016.08.009	https://doi.org/10.1016/j.drudis.2016.08.009	PROPN
ecletica-1322	296	13	https://doi.org/10.2174/157340911795677602	https://doi.org/10.2174/157340911795677602	PROPN
ecletica-1322	296	14	https://doi.org/10.2174/157340911795677602	https://doi.org/10.2174/157340911795677602	NOUN
ecletica-1322	296	15	https://doi.org/10.2174/157340911795677602	https://doi.org/10.2174/157340911795677602	NOUN
ecletica-1322	296	16	https://doi.org/10.2174/157340911795677602	https://doi.org/10.2174/157340911795677602	PROPN
ecletica-1322	296	17	https://doi.org/10.26538/tjnpr/v6i1.16	https://doi.org/10.26538/tjnpr/v6i1.16	PROPN
ecletica-1322	296	18	https://doi.org/10.26538/tjnpr/v6i1.16	https://doi.org/10.26538/tjnpr/v6i1.16	PROPN
ecletica-1322	296	19	https://doi.org/10.26538/tjnpr/v6i1.16	https://doi.org/10.26538/tjnpr/v6i1.16	PROPN
ecletica-1322	296	20	https://doi.org/10.26538/tjnpr/v6i1.16	https://doi.org/10.26538/tjnpr/v6i1.16	PROPN
ecletica-1322	296	21	https://doi.org/10.26538/tjnpr/v6i1.16	https://doi.org/10.26538/tjnpr/v6i1.16	PROPN
ecletica-1322	296	22	https://doi.org/10.26538/tjnpr/v6i1.16	https://doi.org/10.26538/tjnpr/v6i1.16	PROPN
ecletica-1322	296	23	https://doi.org/10.1155/2016/9258578	https://doi.org/10.1155/2016/9258578	PROPN
ecletica-1322	296	24	https://doi.org/10.1155/2016/9258578	https://doi.org/10.1155/2016/9258578	PROPN
ecletica-1322	296	25	https://doi.org/10.1155/2016/9258578	https://doi.org/10.1155/2016/9258578	PROPN
ecletica-1322	296	26	https://doi.org/10.1155/2016/9258578	https://doi.org/10.1155/2016/9258578	PROPN
ecletica-1322	296	27	https://doi.org/10.1155/2016/9258578	https://doi.org/10.1155/2016/9258578	PROPN
ecletica-1322	296	28	https://doi.org/10.1155/2020/6735232	https://doi.org/10.1155/2020/6735232	PROPN
ecletica-1322	297	1	https://doi.org/10.1155/2020/6735232	https://doi.org/10.1155/2020/6735232	PROPN
ecletica-1322	297	2	https://doi.org/10.1155/2020/6735232	https://doi.org/10.1155/2020/6735232	PROPN
ecletica-1322	298	1	https://doi.org/10.1155/2020/6735232	https://doi.org/10.1155/2020/6735232	PROPN
ecletica-1322	298	2	https://doi.org/10.1155/2020/6735232	https://doi.org/10.1155/2020/6735232	PROPN
ecletica-1322	298	3	https://doi.org/10.1007/s42250-021-00276-2	https://doi.org/10.1007/s42250-021-00276-2	X
ecletica-1322	298	4	https://doi.org/10.1007/s42250-021-00276-2	https://doi.org/10.1007/s42250-021-00276-2	X
ecletica-1322	299	1	https://doi.org/10.1007/s42250-021-00276-2	https://doi.org/10.1007/s42250-021-00276-2	X
ecletica-1322	299	2	https://doi.org/10.1007/s42250-021-00276-2	https://doi.org/10.1007/s42250-021-00276-2	NOUN
ecletica-1322	299	3	https://doi.org/10.1007/s42250-021-00276-2	https://doi.org/10.1007/s42250-021-00276-2	NOUN
ecletica-1322	299	4	https://doi.org/10.1016/j.dib.2021.107441	https://doi.org/10.1016/j.dib.2021.107441	PUNCT
ecletica-1322	299	5	https://doi.org/10.1016/j.dib.2021.107441	https://doi.org/10.1016/j.dib.2021.107441	X
ecletica-1322	300	1	https://doi.org/10.1016/j.dib.2021.107441	https://doi.org/10.1016/j.dib.2021.107441	PUNCT
ecletica-1322	300	2	https://doi.org/10.1016/j.dib.2021.107441	https://doi.org/10.1016/j.dib.2021.107441	X
ecletica-1322	300	3	https://doi.org/10.1016/j.dib.2021.107441	https://doi.org/10.1016/j.dib.2021.107441	NOUN
ecletica-1322	300	4	https://doi.org/10.1016/j.dib.2021.107441	https://doi.org/10.1016/j.dib.2021.107441	PROPN
ecletica-1322	301	1	https://doi.org/10.1016/j.dib.2021.107441	https://doi.org/10.1016/j.dib.2021.107441	PROPN
ecletica-1322	302	1	https://doi.org/10.1016/j.prmcm.2022.100054	https://doi.org/10.1016/j.prmcm.2022.100054	ADV
ecletica-1322	302	2	https://doi.org/10.1016/j.prmcm.2022.100054	https://doi.org/10.1016/j.prmcm.2022.100054	ADV
ecletica-1322	302	3	https://doi.org/10.1016/j.prmcm.2022.100054	https://doi.org/10.1016/j.prmcm.2022.100054	ADV
ecletica-1322	302	4	https://doi.org/10.1016/j.prmcm.2022.100054	https://doi.org/10.1016/j.prmcm.2022.100054	ADV
ecletica-1322	302	5	https://doi.org/10.1016/j.prmcm.2022.100054	https://doi.org/10.1016/j.prmcm.2022.100054	ADJ
ecletica-1322	302	6	https://doi.org/10.1016/j.prmcm.2022.100054	https://doi.org/10.1016/j.prmcm.2022.100054	ADJ
ecletica-1322	302	7	https://doi.org/10.1016/j.heliyon.2020.e03926	https://doi.org/10.1016/j.heliyon.2020.e03926	NOUN
ecletica-1322	302	8	https://doi.org/10.1016/j.heliyon.2020.e03926	https://doi.org/10.1016/j.heliyon.2020.e03926	NOUN
ecletica-1322	302	9	https://doi.org/10.1016/j.heliyon.2020.e03926	https://doi.org/10.1016/j.heliyon.2020.e03926	NOUN
ecletica-1322	302	10	https://doi.org/10.1016/j.heliyon.2020.e03926	https://doi.org/10.1016/j.heliyon.2020.e03926	NOUN
ecletica-1322	302	11	https://doi.org/10.1016/j.heliyon.2020.e03926	https://doi.org/10.1016/j.heliyon.2020.e03926	NOUN
ecletica-1322	302	12	https://doi.org/10.1016/j.heliyon.2020.e03926	https://doi.org/10.1016/j.heliyon.2020.e03926	NOUN
ecletica-1322	302	13	https://doi.org/10.1007/978-94-007-6178-0_100975-1	https://doi.org/10.1007/978-94-007-6178-0_100975-1	ADJ
ecletica-1322	302	14	https://doi.org/10.1007/978-94-007-6178-0_100975-1	https://doi.org/10.1007/978-94-007-6178-0_100975-1	ADJ
ecletica-1322	302	15	https://doi.org/10.1007/978-94-007-6178-0_100975-1	https://doi.org/10.1007/978-94-007-6178-0_100975-1	ADJ
ecletica-1322	302	16	https://doi.org/10.1007/978-94-007-6178-0_100975-1	https://doi.org/10.1007/978-94-007-6178-0_100975-1	ADJ
ecletica-1322	303	1	http://s-o-i.org/1.15/ijarbs-2016-3-7-26	http://s-o-i.org/1.15/ijarbs-2016-3-7-26	NOUN
ecletica-1322	303	2	http://s-o-i.org/1.15/ijarbs-2016-3-7-26	http://s-o-i.org/1.15/ijarbs-2016-3-7-26	PROPN
ecletica-1322	303	3	http://s-o-i.org/1.15/ijarbs-2016-3-7-26	http://s-o-i.org/1.15/ijarbs-2016-3-7-26	PROPN
ecletica-1322	303	4	https://doi.org/10.7314/apjcp.2015.16.9.3817	https://doi.org/10.7314/apjcp.2015.16.9.3817	PROPN
ecletica-1322	303	5	https://doi.org/10.7314/apjcp.2015.16.9.3817	https://doi.org/10.7314/apjcp.2015.16.9.3817	PROPN
ecletica-1322	303	6	https://doi.org/10.7314/apjcp.2015.16.9.3817	https://doi.org/10.7314/apjcp.2015.16.9.3817	PROPN
ecletica-1322	303	7	https://doi.org/10.7314/apjcp.2015.16.9.3817	https://doi.org/10.7314/apjcp.2015.16.9.3817	PROPN
ecletica-1322	303	8	https://doi.org/10.7314/apjcp.2015.16.9.3817	https://doi.org/10.7314/apjcp.2015.16.9.3817	PROPN
ecletica-1322	303	9	https://doi.org/10.7314/apjcp.2015.16.9.3817	https://doi.org/10.7314/apjcp.2015.16.9.3817	PROPN
ecletica-1322	303	10	https://doi.org/10.3390/ijms161226202	https://doi.org/10.3390/ijms161226202	PROPN
ecletica-1322	303	11	https://doi.org/10.3390/ijms161226202	https://doi.org/10.3390/ijms161226202	PROPN
ecletica-1322	303	12	https://doi.org/10.3390/ijms161226202	https://doi.org/10.3390/ijms161226202	PROPN
ecletica-1322	303	13	https://doi.org/10.3390/ijms161226202	https://doi.org/10.3390/ijms161226202	PROPN
ecletica-1322	303	14	https://doi.org/10.5772/intechopen.72840	https://doi.org/10.5772/intechopen.72840	PROPN
ecletica-1322	303	15	https://doi.org/10.5772/intechopen.72840	https://doi.org/10.5772/intechopen.72840	PROPN
ecletica-1322	303	16	https://doi.org/10.5772/intechopen.72840	https://doi.org/10.5772/intechopen.72840	PROPN
ecletica-1322	303	17	https://doi.org/10.5772/intechopen.72840	https://doi.org/10.5772/intechopen.72840	PROPN
ecletica-1322	303	18	https://doi.org/10.5958/0974-360x.2017.00574.1	https://doi.org/10.5958/0974-360x.2017.00574.1	NUM
ecletica-1322	303	19	https://doi.org/10.5958/0974-360x.2017.00574.1	https://doi.org/10.5958/0974-360x.2017.00574.1	NUM
ecletica-1322	303	20	https://doi.org/10.5958/0974-360x.2017.00574.1	https://doi.org/10.5958/0974-360x.2017.00574.1	NUM
ecletica-1322	303	21	https://doi.org/10.5958/0974-360x.2017.00574.1	https://doi.org/10.5958/0974-360x.2017.00574.1	NUM
ecletica-1322	303	22	https://doi.org/10.1053/j.gastro.2009.07.060	https://doi.org/10.1053/j.gastro.2009.07.060	NOUN
ecletica-1322	303	23	https://doi.org/10.1053/j.gastro.2009.07.060	https://doi.org/10.1053/j.gastro.2009.07.060	NOUN
ecletica-1322	303	24	https://doi.org/10.1053/j.gastro.2009.07.060	https://doi.org/10.1053/j.gastro.2009.07.060	NOUN
ecletica-1322	303	25	https://doi.org/10.1053/j.gastro.2009.07.060	https://doi.org/10.1053/j.gastro.2009.07.060	NOUN