id	sid	tid	token	lemma	pos
ecletica-1329	1	1	original	original	ADJ
ecletica-1329	1	2	article	article	NOUN
ecletica-1329	1	3	revista.iq.unesp.br	revista.iq.unesp.br	PROPN
ecletica-1329	1	4	|	|	ADJ
ecletica-1329	1	5	vol	vol	NOUN
ecletica-1329	1	6	.	.	PUNCT
ecletica-1329	2	1	48	48	NUM
ecletica-1329	2	2	|	|	ADV
ecletica-1329	2	3	n.	n.	NOUN
ecletica-1329	2	4	1	1	NUM
ecletica-1329	3	1	|	|	ADV
ecletica-1329	3	2	2023	2023	NUM
ecletica-1329	3	3	|	|	ADV
ecletica-1329	3	4	55	55	NUM
ecletica-1329	3	5	eclética	eclética	NOUN
ecletica-1329	3	6	química	química	PROPN
ecletica-1329	3	7	,	,	PUNCT
ecletica-1329	3	8	vol	vol	NOUN
ecletica-1329	3	9	.	.	PROPN
ecletica-1329	3	10	48	48	NUM
ecletica-1329	3	11	,	,	PUNCT
ecletica-1329	3	12	n.	n.	NOUN
ecletica-1329	3	13	1	1	NUM
ecletica-1329	3	14	,	,	PUNCT
ecletica-1329	3	15	2023	2023	NUM
ecletica-1329	3	16	,	,	PUNCT
ecletica-1329	3	17	55	55	NUM
ecletica-1329	3	18	-	-	SYM
ecletica-1329	3	19	71	71	NUM
ecletica-1329	3	20	issn	issn	NOUN
ecletica-1329	3	21	:	:	PUNCT
ecletica-1329	3	22	1678	1678	NUM
ecletica-1329	3	23	-	-	SYM
ecletica-1329	3	24	4618	4618	NUM
ecletica-1329	3	25	doi	doi	NOUN
ecletica-1329	3	26	:	:	PUNCT
ecletica-1329	3	27	10.26850/1678	10.26850/1678	NUM
ecletica-1329	3	28	-	-	PUNCT
ecletica-1329	3	29	4618eqj.v48.1.2023.p55	4618eqj.v48.1.2023.p55	NUM
ecletica-1329	3	30	-	-	PUNCT
ecletica-1329	3	31	71	71	NUM
ecletica-1329	3	32	quantitative	quantitative	ADJ
ecletica-1329	3	33	structure	structure	NOUN
ecletica-1329	3	34	-	-	PUNCT
ecletica-1329	3	35	activity	activity	NOUN
ecletica-1329	3	36	relationship	relationship	NOUN
ecletica-1329	3	37	,	,	PUNCT
ecletica-1329	3	38	molecular	molecular	ADJ
ecletica-1329	3	39	docking	docking	NOUN
ecletica-1329	3	40	and	and	CCONJ
ecletica-1329	3	41	admet	admet	PROPN
ecletica-1329	3	42	screening	screening	NOUN
ecletica-1329	3	43	of	of	ADP
ecletica-1329	3	44	tetrahydroquinoline	tetrahydroquinoline	ADJ
ecletica-1329	3	45	derivatives	derivative	NOUN
ecletica-1329	3	46	as	as	ADP
ecletica-1329	3	47	antismall	antismall	PROPN
ecletica-1329	3	48	cell	cell	NOUN
ecletica-1329	3	49	lung	lung	NOUN
ecletica-1329	3	50	cancer	cancer	NOUN
ecletica-1329	3	51	agents	agent	NOUN
ecletica-1329	3	52	ehimen	ehimen	PROPN
ecletica-1329	3	53	annastasia	annastasia	PROPN
ecletica-1329	3	54	erazua1	erazua1	PROPN
ecletica-1329	3	55	,	,	PUNCT
ecletica-1329	3	56	abel	abel	PROPN
ecletica-1329	3	57	kolawole	kolawole	VERB
ecletica-1329	3	58	oyebamiji2	oyebamiji2	PROPN
ecletica-1329	4	1	+	+	PROPN
ecletica-1329	4	2	,	,	PUNCT
ecletica-1329	4	3	sunday	sunday	PROPN
ecletica-1329	4	4	adewale	adewale	PROPN
ecletica-1329	4	5	akintelu3	akintelu3	PROPN
ecletica-1329	4	6	,	,	PUNCT
ecletica-1329	4	7	pelumi	pelumi	PROPN
ecletica-1329	4	8	daniel	daniel	PROPN
ecletica-1329	4	9	adewole4	adewole4	PROPN
ecletica-1329	4	10	,	,	PUNCT
ecletica-1329	4	11	adedayo	adedayo	PROPN
ecletica-1329	4	12	adelakun5	adelakun5	PROPN
ecletica-1329	4	13	,	,	PUNCT
ecletica-1329	4	14	babatunde	babatunde	PROPN
ecletica-1329	4	15	benjamin	benjamin	PROPN
ecletica-1329	4	16	adeleke1	adeleke1	PROPN
ecletica-1329	4	17	1	1	NUM
ecletica-1329	4	18	.	.	PUNCT
ecletica-1329	5	1	university	university	NOUN
ecletica-1329	5	2	of	of	ADP
ecletica-1329	5	3	ibadan	ibadan	PROPN
ecletica-1329	5	4	,	,	PUNCT
ecletica-1329	5	5	department	department	NOUN
ecletica-1329	5	6	of	of	ADP
ecletica-1329	5	7	chemistry	chemistry	NOUN
ecletica-1329	5	8	,	,	PUNCT
ecletica-1329	5	9	ibadan	ibadan	PROPN
ecletica-1329	5	10	,	,	PUNCT
ecletica-1329	5	11	nigeria	nigeria	PROPN
ecletica-1329	5	12	.	.	PUNCT
ecletica-1329	6	1	2	2	X
ecletica-1329	6	2	.	.	X
ecletica-1329	6	3	bowen	bowen	PROPN
ecletica-1329	6	4	university	university	PROPN
ecletica-1329	6	5	,	,	PUNCT
ecletica-1329	6	6	department	department	NOUN
ecletica-1329	6	7	of	of	ADP
ecletica-1329	6	8	chemistry	chemistry	NOUN
ecletica-1329	6	9	and	and	CCONJ
ecletica-1329	6	10	industrial	industrial	ADJ
ecletica-1329	6	11	chemistry	chemistry	NOUN
ecletica-1329	6	12	,	,	PUNCT
ecletica-1329	6	13	iwo	iwo	PROPN
ecletica-1329	6	14	,	,	PUNCT
ecletica-1329	6	15	nigeria	nigeria	PROPN
ecletica-1329	6	16	.	.	PUNCT
ecletica-1329	7	1	3	3	X
ecletica-1329	7	2	.	.	X
ecletica-1329	7	3	beijing	beijing	PROPN
ecletica-1329	7	4	institute	institute	PROPN
ecletica-1329	7	5	of	of	ADP
ecletica-1329	7	6	technology	technology	PROPN
ecletica-1329	7	7	,	,	PUNCT
ecletica-1329	7	8	school	school	NOUN
ecletica-1329	7	9	of	of	ADP
ecletica-1329	7	10	chemistry	chemistry	NOUN
ecletica-1329	7	11	and	and	CCONJ
ecletica-1329	7	12	chemical	chemical	PROPN
ecletica-1329	7	13	engineering	engineering	NOUN
ecletica-1329	7	14	,	,	PUNCT
ecletica-1329	7	15	beijing	beijing	PROPN
ecletica-1329	7	16	,	,	PUNCT
ecletica-1329	7	17	china	china	PROPN
ecletica-1329	7	18	.	.	PUNCT
ecletica-1329	8	1	4	4	NUM
ecletica-1329	8	2	.	.	NOUN
ecletica-1329	8	3	elizade	elizade	PROPN
ecletica-1329	8	4	university	university	PROPN
ecletica-1329	8	5	,	,	PUNCT
ecletica-1329	8	6	department	department	NOUN
ecletica-1329	8	7	of	of	ADP
ecletica-1329	8	8	medical	medical	ADJ
ecletica-1329	8	9	laboratory	laboratory	NOUN
ecletica-1329	8	10	science	science	NOUN
ecletica-1329	8	11	,	,	PUNCT
ecletica-1329	8	12	ilara	ilara	NOUN
ecletica-1329	8	13	-	-	PUNCT
ecletica-1329	8	14	mokin	mokin	PROPN
ecletica-1329	8	15	,	,	PUNCT
ecletica-1329	8	16	nigeria	nigeria	PROPN
ecletica-1329	8	17	.	.	PUNCT
ecletica-1329	9	1	5	5	X
ecletica-1329	9	2	.	.	X
ecletica-1329	9	3	southeast	southeast	PROPN
ecletica-1329	9	4	iowa	iowa	PROPN
ecletica-1329	9	5	regional	regional	PROPN
ecletica-1329	9	6	medical	medical	ADJ
ecletica-1329	9	7	center	center	NOUN
ecletica-1329	9	8	,	,	PUNCT
ecletica-1329	9	9	iowa	iowa	PROPN
ecletica-1329	9	10	,	,	PUNCT
ecletica-1329	9	11	united	united	PROPN
ecletica-1329	9	12	states	state	NOUN
ecletica-1329	9	13	.	.	PUNCT
ecletica-1329	10	1	+	+	X
ecletica-1329	10	2	corresponding	correspond	VERB
ecletica-1329	10	3	author	author	NOUN
ecletica-1329	10	4	:	:	PUNCT
ecletica-1329	10	5	abel	abel	PROPN
ecletica-1329	10	6	kolawole	kolawole	PROPN
ecletica-1329	10	7	oyebamiji	oyebamiji	PROPN
ecletica-1329	10	8	,	,	PUNCT
ecletica-1329	10	9	phone	phone	NOUN
ecletica-1329	10	10	:	:	PUNCT
ecletica-1329	10	11	+2348032493676	+2348032493676	NUM
ecletica-1329	10	12	,	,	PUNCT
ecletica-1329	10	13	email	email	NOUN
ecletica-1329	10	14	address	address	NOUN
ecletica-1329	10	15	:	:	PUNCT
ecletica-1329	10	16	abeloyebamiji@gmail.com	abeloyebamiji@gmail.com	X
ecletica-1329	10	17	article	article	NOUN
ecletica-1329	10	18	info	info	NOUN
ecletica-1329	10	19	article	article	NOUN
ecletica-1329	10	20	history	history	NOUN
ecletica-1329	10	21	:	:	PUNCT
ecletica-1329	10	22	received	receive	VERB
ecletica-1329	10	23	:	:	PUNCT
ecletica-1329	10	24	april	april	PROPN
ecletica-1329	10	25	19	19	NUM
ecletica-1329	10	26	,	,	PUNCT
ecletica-1329	10	27	2022	2022	NUM
ecletica-1329	10	28	accepted	accept	VERB
ecletica-1329	10	29	:	:	PUNCT
ecletica-1329	10	30	november	november	PROPN
ecletica-1329	10	31	7	7	NUM
ecletica-1329	10	32	,	,	PUNCT
ecletica-1329	10	33	2022	2022	NUM
ecletica-1329	10	34	published	publish	VERB
ecletica-1329	10	35	:	:	PUNCT
ecletica-1329	10	36	january	january	PROPN
ecletica-1329	10	37	01	01	NUM
ecletica-1329	10	38	,	,	PUNCT
ecletica-1329	10	39	2023	2023	NUM
ecletica-1329	10	40	keywords	keyword	NOUN
ecletica-1329	10	41	:	:	PUNCT
ecletica-1329	11	1	1	1	X
ecletica-1329	11	2	.	.	X
ecletica-1329	11	3	tetrahydroquinoline	tetrahydroquinoline	PROPN
ecletica-1329	11	4	2	2	NUM
ecletica-1329	11	5	.	.	PUNCT
ecletica-1329	11	6	lung	lung	NOUN
ecletica-1329	11	7	cancer	cancer	NOUN
ecletica-1329	11	8	3	3	PROPN
ecletica-1329	11	9	.	.	PUNCT
ecletica-1329	11	10	qsar	qsar	PROPN
ecletica-1329	11	11	4	4	NUM
ecletica-1329	11	12	.	.	X
ecletica-1329	12	1	molecular	molecular	ADJ
ecletica-1329	12	2	docking	docking	NOUN
ecletica-1329	12	3	5	5	NUM
ecletica-1329	12	4	.	.	PUNCT
ecletica-1329	12	5	admet	admet	PROPN
ecletica-1329	12	6	section	section	NOUN
ecletica-1329	12	7	editors	editor	NOUN
ecletica-1329	12	8	:	:	PUNCT
ecletica-1329	12	9	assis	assis	PROPN
ecletica-1329	12	10	vicente	vicente	PROPN
ecletica-1329	12	11	benedetti	benedetti	PROPN
ecletica-1329	12	12	abstract	abstract	PROPN
ecletica-1329	12	13	:	:	PUNCT
ecletica-1329	12	14	lung	lung	NOUN
ecletica-1329	12	15	carcinoma	carcinoma	NOUN
ecletica-1329	12	16	(	(	PUNCT
ecletica-1329	12	17	lc	lc	NOUN
ecletica-1329	12	18	)	)	PUNCT
ecletica-1329	12	19	is	be	AUX
ecletica-1329	12	20	responsible	responsible	ADJ
ecletica-1329	12	21	for	for	ADP
ecletica-1329	12	22	almost	almost	ADV
ecletica-1329	12	23	onethird	onethird	NOUN
ecletica-1329	12	24	of	of	ADP
ecletica-1329	12	25	all	all	DET
ecletica-1329	12	26	cancer	cancer	NOUN
ecletica-1329	12	27	fatalities	fatality	NOUN
ecletica-1329	12	28	worldwide	worldwide	ADV
ecletica-1329	12	29	.	.	PUNCT
ecletica-1329	13	1	tetrahydroquinoline	tetrahydroquinoline	PROPN
ecletica-1329	13	2	is	be	AUX
ecletica-1329	13	3	an	an	DET
ecletica-1329	13	4	organic	organic	ADJ
ecletica-1329	13	5	molecule	molecule	NOUN
ecletica-1329	13	6	that	that	PRON
ecletica-1329	13	7	is	be	AUX
ecletica-1329	13	8	the	the	DET
ecletica-1329	13	9	semi	semi	ADJ
ecletica-1329	13	10	-	-	ADJ
ecletica-1329	13	11	hydrogenated	hydrogenated	ADJ
ecletica-1329	13	12	derivative	derivative	NOUN
ecletica-1329	13	13	of	of	ADP
ecletica-1329	13	14	quinoline	quinoline	NOUN
ecletica-1329	13	15	and	and	CCONJ
ecletica-1329	13	16	could	could	AUX
ecletica-1329	13	17	be	be	AUX
ecletica-1329	13	18	found	find	VERB
ecletica-1329	13	19	in	in	ADP
ecletica-1329	13	20	several	several	ADJ
ecletica-1329	13	21	naturally	naturally	ADV
ecletica-1329	13	22	occurring	occur	VERB
ecletica-1329	13	23	compounds	compound	NOUN
ecletica-1329	13	24	such	such	ADJ
ecletica-1329	13	25	as	as	ADP
ecletica-1329	13	26	flindersine	flindersine	NOUN
ecletica-1329	13	27	,	,	PUNCT
ecletica-1329	13	28	oricine	oricine	VERB
ecletica-1329	13	29	etc	etc	X
ecletica-1329	13	30	.	.	PUNCT
ecletica-1329	14	1	some	some	DET
ecletica-1329	14	2	tetrahydroquinoline	tetrahydroquinoline	ADJ
ecletica-1329	14	3	derivatives	derivative	NOUN
ecletica-1329	14	4	with	with	ADP
ecletica-1329	14	5	pyrazole	pyrazole	NOUN
ecletica-1329	14	6	and	and	CCONJ
ecletica-1329	14	7	hydrazide	hydrazide	ADJ
ecletica-1329	14	8	moieties	moiety	NOUN
ecletica-1329	14	9	were	be	AUX
ecletica-1329	14	10	evaluated	evaluate	VERB
ecletica-1329	14	11	in	in	ADP
ecletica-1329	14	12	silico	silico	NOUN
ecletica-1329	14	13	against	against	ADP
ecletica-1329	14	14	a549	a549	PROPN
ecletica-1329	14	15	(	(	PUNCT
ecletica-1329	14	16	human	human	ADJ
ecletica-1329	14	17	lung	lung	NOUN
ecletica-1329	14	18	cancer	cancer	NOUN
ecletica-1329	14	19	cell	cell	NOUN
ecletica-1329	14	20	lines	line	NOUN
ecletica-1329	14	21	)	)	PUNCT
ecletica-1329	14	22	.	.	PUNCT
ecletica-1329	15	1	the	the	DET
ecletica-1329	15	2	quantitative	quantitative	ADJ
ecletica-1329	15	3	structural	structural	ADJ
ecletica-1329	15	4	-	-	PUNCT
ecletica-1329	15	5	activity	activity	NOUN
ecletica-1329	15	6	relationship	relationship	NOUN
ecletica-1329	15	7	(	(	PUNCT
ecletica-1329	15	8	qsar	qsar	NOUN
ecletica-1329	15	9	)	)	PUNCT
ecletica-1329	15	10	model	model	NOUN
ecletica-1329	15	11	created	create	VERB
ecletica-1329	15	12	was	be	AUX
ecletica-1329	15	13	statistically	statistically	ADV
ecletica-1329	15	14	significant	significant	ADJ
ecletica-1329	15	15	with	with	ADP
ecletica-1329	15	16	validation	validation	NOUN
ecletica-1329	15	17	metrics	metric	NOUN
ecletica-1329	15	18	of	of	ADP
ecletica-1329	15	19	r2	r2	PROPN
ecletica-1329	15	20	(	(	PUNCT
ecletica-1329	15	21	0.9525	0.9525	NUM
ecletica-1329	15	22	)	)	PUNCT
ecletica-1329	15	23	,	,	PUNCT
ecletica-1329	15	24	r2adj	r2adj	X
ecletica-1329	15	25	(	(	PUNCT
ecletica-1329	15	26	0.9314	0.9314	NUM
ecletica-1329	15	27	)	)	PUNCT
ecletica-1329	15	28	,	,	PUNCT
ecletica-1329	15	29	and	and	CCONJ
ecletica-1329	15	30	cv.r	cv.r	NUM
ecletica-1329	15	31	(	(	PUNCT
ecletica-1329	15	32	0.9719	0.9719	NUM
ecletica-1329	15	33	)	)	PUNCT
ecletica-1329	15	34	.	.	PUNCT
ecletica-1329	16	1	the	the	DET
ecletica-1329	16	2	molecular	molecular	ADJ
ecletica-1329	16	3	docking	docking	NOUN
ecletica-1329	16	4	analysis	analysis	NOUN
ecletica-1329	16	5	revealed	reveal	VERB
ecletica-1329	16	6	that	that	SCONJ
ecletica-1329	16	7	compound	compound	NOUN
ecletica-1329	16	8	c14	c14	PROPN
ecletica-1329	16	9	demonstrated	demonstrate	VERB
ecletica-1329	16	10	the	the	DET
ecletica-1329	16	11	best	good	ADJ
ecletica-1329	16	12	binding	bind	VERB
ecletica-1329	16	13	affinity	affinity	NOUN
ecletica-1329	16	14	towards	towards	ADP
ecletica-1329	16	15	the	the	DET
ecletica-1329	16	16	studied	study	VERB
ecletica-1329	16	17	protein	protein	NOUN
ecletica-1329	16	18	with	with	ADP
ecletica-1329	16	19	binding	bind	VERB
ecletica-1329	16	20	affinity	affinity	NOUN
ecletica-1329	16	21	value	value	NOUN
ecletica-1329	16	22	of	of	ADP
ecletica-1329	16	23	–	–	PUNCT
ecletica-1329	16	24	10.1	10.1	NUM
ecletica-1329	16	25	kcal	kcal	PROPN
ecletica-1329	16	26	mol–-1	mol–-1	PROPN
ecletica-1329	16	27	(	(	PUNCT
ecletica-1329	16	28	4lrm	4lrm	NOUN
ecletica-1329	16	29	)	)	PUNCT
ecletica-1329	16	30	.	.	PUNCT
ecletica-1329	17	1	this	this	PRON
ecletica-1329	17	2	is	be	AUX
ecletica-1329	17	3	in	in	ADP
ecletica-1329	17	4	accordance	accordance	NOUN
ecletica-1329	17	5	with	with	ADP
ecletica-1329	17	6	the	the	DET
ecletica-1329	17	7	experimental	experimental	ADJ
ecletica-1329	17	8	result	result	NOUN
ecletica-1329	17	9	(	(	PUNCT
ecletica-1329	17	10	ic50	ic50	PROPN
ecletica-1329	17	11	=	=	PROPN
ecletica-1329	17	12	0.69	0.69	NUM
ecletica-1329	17	13	)	)	PUNCT
ecletica-1329	17	14	.	.	PUNCT
ecletica-1329	18	1	the	the	DET
ecletica-1329	18	2	factors	factor	NOUN
ecletica-1329	18	3	observed	observe	VERB
ecletica-1329	18	4	for	for	ADP
ecletica-1329	18	5	adme&t	adme&t	PROPN
ecletica-1329	18	6	correlated	correlate	VERB
ecletica-1329	18	7	well	well	ADV
ecletica-1329	18	8	with	with	ADP
ecletica-1329	18	9	the	the	DET
ecletica-1329	18	10	factors	factor	NOUN
ecletica-1329	18	11	observed	observe	VERB
ecletica-1329	18	12	for	for	ADP
ecletica-1329	18	13	the	the	DET
ecletica-1329	18	14	referenced	reference	VERB
ecletica-1329	18	15	drug	drug	NOUN
ecletica-1329	18	16	.	.	PUNCT
ecletica-1329	19	1	this	this	DET
ecletica-1329	19	2	study	study	NOUN
ecletica-1329	19	3	indicates	indicate	VERB
ecletica-1329	19	4	that	that	SCONJ
ecletica-1329	19	5	compounds	compound	VERB
ecletica-1329	19	6	c1	c1	PROPN
ecletica-1329	19	7	and	and	CCONJ
ecletica-1329	19	8	c9	c9	PROPN
ecletica-1329	19	9	can	can	AUX
ecletica-1329	19	10	be	be	AUX
ecletica-1329	19	11	further	far	ADV
ecletica-1329	19	12	developed	develop	VERB
ecletica-1329	19	13	as	as	ADP
ecletica-1329	19	14	anti	anti	ADJ
ecletica-1329	19	15	-	-	ADJ
ecletica-1329	19	16	epidermal	epidermal	ADJ
ecletica-1329	19	17	growth	growth	NOUN
ecletica-1329	19	18	factor	factor	NOUN
ecletica-1329	19	19	receptor	receptor	NOUN
ecletica-1329	19	20	(	(	PUNCT
ecletica-1329	19	21	egfr	egfr	X
ecletica-1329	19	22	)	)	PUNCT
ecletica-1329	19	23	compounds	compound	NOUN
ecletica-1329	19	24	.	.	PUNCT
ecletica-1329	20	1	thus	thus	ADV
ecletica-1329	20	2	,	,	PUNCT
ecletica-1329	20	3	our	our	PRON
ecletica-1329	20	4	findings	finding	NOUN
ecletica-1329	20	5	may	may	AUX
ecletica-1329	20	6	open	open	VERB
ecletica-1329	20	7	door	door	NOUN
ecletica-1329	20	8	for	for	ADP
ecletica-1329	20	9	the	the	DET
ecletica-1329	20	10	design	design	NOUN
ecletica-1329	20	11	and	and	CCONJ
ecletica-1329	20	12	development	development	NOUN
ecletica-1329	20	13	of	of	ADP
ecletica-1329	20	14	library	library	NOUN
ecletica-1329	20	15	of	of	ADP
ecletica-1329	20	16	efficient	efficient	ADJ
ecletica-1329	20	17	tetrahydroquinolinebased	tetrahydroquinolinebase	VERB
ecletica-1329	20	18	drug	drug	NOUN
ecletica-1329	20	19	-	-	PUNCT
ecletica-1329	20	20	like	like	ADJ
ecletica-1329	20	21	compounds	compound	NOUN
ecletica-1329	20	22	as	as	ADP
ecletica-1329	20	23	potential	potential	ADJ
ecletica-1329	20	24	anti	anti	ADJ
ecletica-1329	20	25	-	-	ADJ
ecletica-1329	20	26	lc	lc	ADJ
ecletica-1329	20	27	agents	agent	NOUN
ecletica-1329	20	28	.	.	PUNCT
ecletica-1329	21	1	https://revista.iq.unesp.br/index.php/ecletica	https://revista.iq.unesp.br/index.php/ecletica	PROPN
ecletica-1329	21	2	https://doi.org/10.26850/1678-4618eqj.v48.1.2023.p55-71	https://doi.org/10.26850/1678-4618eqj.v48.1.2023.p55-71	PROPN
ecletica-1329	21	3	mailto:abeloyebamiji@gmail.com	mailto:abeloyebamiji@gmail.com	X
ecletica-1329	22	1	https://orcid.org/0000-0001-6887-6381	https://orcid.org/0000-0001-6887-6381	ADP
ecletica-1329	22	2	https://orcid.org/0000-0002-8932-6327	https://orcid.org/0000-0002-8932-6327	PROPN
ecletica-1329	23	1	https://orcid.org/0000-0001-8919-3029	https://orcid.org/0000-0001-8919-3029	PROPN
ecletica-1329	23	2	https://orcid.org/0000-0002-0229-2540	https://orcid.org/0000-0002-0229-2540	PROPN
ecletica-1329	23	3	https://orcid.org/0000-0001-7951-9275	https://orcid.org/0000-0001-7951-9275	PROPN
ecletica-1329	23	4	https://orcid.org/0000-0003-4000-9803	https://orcid.org/0000-0003-4000-9803	VERB
ecletica-1329	23	5	original	original	ADJ
ecletica-1329	23	6	article	article	NOUN
ecletica-1329	23	7	revista.iq.unesp.br	revista.iq.unesp.br	PROPN
ecletica-1329	23	8	56	56	NUM
ecletica-1329	23	9	eclética	eclética	PROPN
ecletica-1329	23	10	química	química	PROPN
ecletica-1329	23	11	,	,	PUNCT
ecletica-1329	23	12	vol	vol	NOUN
ecletica-1329	23	13	.	.	PROPN
ecletica-1329	23	14	48	48	NUM
ecletica-1329	23	15	,	,	PUNCT
ecletica-1329	23	16	n.	n.	NOUN
ecletica-1329	23	17	1	1	NUM
ecletica-1329	23	18	,	,	PUNCT
ecletica-1329	23	19	2023	2023	NUM
ecletica-1329	23	20	,	,	PUNCT
ecletica-1329	23	21	55	55	NUM
ecletica-1329	23	22	-	-	SYM
ecletica-1329	23	23	71	71	NUM
ecletica-1329	23	24	issn	issn	NOUN
ecletica-1329	23	25	:	:	PUNCT
ecletica-1329	23	26	1678	1678	NUM
ecletica-1329	23	27	-	-	SYM
ecletica-1329	23	28	4618	4618	NUM
ecletica-1329	23	29	doi	doi	NOUN
ecletica-1329	23	30	:	:	PUNCT
ecletica-1329	23	31	10.26850/1678	10.26850/1678	NUM
ecletica-1329	23	32	-	-	PUNCT
ecletica-1329	23	33	4618eqj.v48.1.2023.p55	4618eqj.v48.1.2023.p55	NUM
ecletica-1329	23	34	-	-	PUNCT
ecletica-1329	23	35	71	71	NUM
ecletica-1329	23	36	1	1	NUM
ecletica-1329	23	37	.	.	PUNCT
ecletica-1329	23	38	introduction	introduction	NOUN
ecletica-1329	23	39	lung	lung	NOUN
ecletica-1329	23	40	carcinoma	carcinoma	NOUN
ecletica-1329	23	41	(	(	PUNCT
ecletica-1329	23	42	lc	lc	NOUN
ecletica-1329	23	43	)	)	PUNCT
ecletica-1329	23	44	leads	lead	VERB
ecletica-1329	23	45	to	to	ADP
ecletica-1329	23	46	the	the	DET
ecletica-1329	23	47	greatest	great	ADJ
ecletica-1329	23	48	number	number	NOUN
ecletica-1329	23	49	of	of	ADP
ecletica-1329	23	50	cancer	cancer	NOUN
ecletica-1329	23	51	-	-	PUNCT
ecletica-1329	23	52	associated	associate	VERB
ecletica-1329	23	53	morbidity	morbidity	NOUN
ecletica-1329	23	54	and	and	CCONJ
ecletica-1329	23	55	death	death	NOUN
ecletica-1329	23	56	across	across	ADP
ecletica-1329	23	57	the	the	DET
ecletica-1329	23	58	globe	globe	NOUN
ecletica-1329	23	59	(	(	PUNCT
ecletica-1329	23	60	siegel	siegel	PROPN
ecletica-1329	23	61	et	et	PROPN
ecletica-1329	23	62	al	al	PROPN
ecletica-1329	23	63	.	.	PROPN
ecletica-1329	23	64	,	,	PUNCT
ecletica-1329	23	65	2016	2016	NUM
ecletica-1329	23	66	)	)	PUNCT
ecletica-1329	23	67	.	.	PUNCT
ecletica-1329	24	1	it	it	PRON
ecletica-1329	24	2	accounted	account	VERB
ecletica-1329	24	3	for	for	ADP
ecletica-1329	24	4	around	around	ADV
ecletica-1329	24	5	one	one	NUM
ecletica-1329	24	6	-	-	PUNCT
ecletica-1329	24	7	third	third	NOUN
ecletica-1329	24	8	of	of	ADP
ecletica-1329	24	9	all	all	DET
ecletica-1329	24	10	cancer	cancer	NOUN
ecletica-1329	24	11	deaths	death	NOUN
ecletica-1329	24	12	worldwide	worldwide	ADV
ecletica-1329	24	13	(	(	PUNCT
ecletica-1329	24	14	ibrahim	ibrahim	NOUN
ecletica-1329	24	15	et	et	PROPN
ecletica-1329	24	16	al	al	PROPN
ecletica-1329	24	17	.	.	PROPN
ecletica-1329	24	18	,	,	PUNCT
ecletica-1329	24	19	2020	2020	NUM
ecletica-1329	24	20	)	)	PUNCT
ecletica-1329	24	21	and	and	CCONJ
ecletica-1329	24	22	is	be	AUX
ecletica-1329	24	23	now	now	ADV
ecletica-1329	24	24	the	the	DET
ecletica-1329	24	25	fourth	fourth	ADJ
ecletica-1329	24	26	most	most	ADV
ecletica-1329	24	27	common	common	ADJ
ecletica-1329	24	28	reason	reason	NOUN
ecletica-1329	24	29	for	for	SCONJ
ecletica-1329	24	30	respiratory	respiratory	ADJ
ecletica-1329	24	31	disease	disease	NOUN
ecletica-1329	24	32	patients	patient	NOUN
ecletica-1329	24	33	to	to	PART
ecletica-1329	24	34	be	be	AUX
ecletica-1329	24	35	admitted	admit	VERB
ecletica-1329	24	36	to	to	ADP
ecletica-1329	24	37	the	the	DET
ecletica-1329	24	38	hospitals	hospital	NOUN
ecletica-1329	24	39	(	(	PUNCT
ecletica-1329	24	40	salim	salim	PROPN
ecletica-1329	24	41	et	et	PROPN
ecletica-1329	24	42	al	al	PROPN
ecletica-1329	24	43	.	.	PROPN
ecletica-1329	24	44	,	,	PUNCT
ecletica-1329	24	45	2011	2011	NUM
ecletica-1329	24	46	)	)	PUNCT
ecletica-1329	24	47	.	.	PUNCT
ecletica-1329	25	1	this	this	DET
ecletica-1329	25	2	disease	disease	NOUN
ecletica-1329	25	3	begins	begin	VERB
ecletica-1329	25	4	as	as	ADP
ecletica-1329	25	5	a	a	DET
ecletica-1329	25	6	primary	primary	ADJ
ecletica-1329	25	7	metastatic	metastatic	ADJ
ecletica-1329	25	8	tumor	tumor	NOUN
ecletica-1329	25	9	in	in	ADP
ecletica-1329	25	10	the	the	DET
ecletica-1329	25	11	lungs	lung	NOUN
ecletica-1329	25	12	and	and	CCONJ
ecletica-1329	25	13	escalate	escalate	VERB
ecletica-1329	25	14	to	to	ADP
ecletica-1329	25	15	other	other	ADJ
ecletica-1329	25	16	region	region	NOUN
ecletica-1329	25	17	of	of	ADP
ecletica-1329	25	18	the	the	DET
ecletica-1329	25	19	body	body	NOUN
ecletica-1329	25	20	.	.	PUNCT
ecletica-1329	26	1	weight	weight	NOUN
ecletica-1329	26	2	loss	loss	NOUN
ecletica-1329	26	3	,	,	PUNCT
ecletica-1329	26	4	difficulty	difficulty	NOUN
ecletica-1329	26	5	in	in	ADP
ecletica-1329	26	6	breathing	breathing	NOUN
ecletica-1329	26	7	,	,	PUNCT
ecletica-1329	26	8	cough	cough	NOUN
ecletica-1329	26	9	(	(	PUNCT
ecletica-1329	26	10	sometimes	sometimes	ADV
ecletica-1329	26	11	with	with	ADP
ecletica-1329	26	12	blood	blood	NOUN
ecletica-1329	26	13	)	)	PUNCT
ecletica-1329	26	14	,	,	PUNCT
ecletica-1329	26	15	and	and	CCONJ
ecletica-1329	26	16	chest	chest	NOUN
ecletica-1329	26	17	pain	pain	NOUN
ecletica-1329	26	18	(	(	PUNCT
ecletica-1329	26	19	wang	wang	PROPN
ecletica-1329	26	20	et	et	PROPN
ecletica-1329	26	21	al	al	PROPN
ecletica-1329	26	22	.	.	PROPN
ecletica-1329	26	23	,	,	PUNCT
ecletica-1329	26	24	2016	2016	NUM
ecletica-1329	26	25	)	)	PUNCT
ecletica-1329	26	26	are	be	AUX
ecletica-1329	26	27	all	all	PRON
ecletica-1329	26	28	known	know	VERB
ecletica-1329	26	29	signs	sign	NOUN
ecletica-1329	26	30	of	of	ADP
ecletica-1329	26	31	lc	lc	PROPN
ecletica-1329	26	32	.	.	PUNCT
ecletica-1329	27	1	genetic	genetic	ADJ
ecletica-1329	27	2	factors	factor	NOUN
ecletica-1329	27	3	,	,	PUNCT
ecletica-1329	27	4	tobacco	tobacco	NOUN
ecletica-1329	27	5	use	use	NOUN
ecletica-1329	27	6	,	,	PUNCT
ecletica-1329	27	7	nutrition	nutrition	NOUN
ecletica-1329	27	8	,	,	PUNCT
ecletica-1329	27	9	air	air	NOUN
ecletica-1329	27	10	pollution	pollution	NOUN
ecletica-1329	27	11	,	,	PUNCT
ecletica-1329	27	12	and	and	CCONJ
ecletica-1329	27	13	obesity	obesity	NOUN
ecletica-1329	27	14	are	be	AUX
ecletica-1329	27	15	some	some	PRON
ecletica-1329	27	16	of	of	ADP
ecletica-1329	27	17	the	the	DET
ecletica-1329	27	18	factors	factor	NOUN
ecletica-1329	27	19	that	that	PRON
ecletica-1329	27	20	have	have	AUX
ecletica-1329	27	21	been	be	AUX
ecletica-1329	27	22	linked	link	VERB
ecletica-1329	27	23	to	to	ADP
ecletica-1329	27	24	lungs	lung	NOUN
ecletica-1329	27	25	cancer	cancer	NOUN
ecletica-1329	27	26	(	(	PUNCT
ecletica-1329	27	27	cassidy	cassidy	PROPN
ecletica-1329	27	28	et	et	PROPN
ecletica-1329	27	29	al	al	PROPN
ecletica-1329	27	30	.	.	PROPN
ecletica-1329	27	31	,	,	PUNCT
ecletica-1329	27	32	2008	2008	NUM
ecletica-1329	27	33	)	)	PUNCT
ecletica-1329	27	34	.	.	PUNCT
ecletica-1329	28	1	small	small	ADJ
ecletica-1329	28	2	cell	cell	NOUN
ecletica-1329	28	3	lung	lung	NOUN
ecletica-1329	28	4	cancer	cancer	NOUN
ecletica-1329	28	5	(	(	PUNCT
ecletica-1329	28	6	sclc	sclc	PROPN
ecletica-1329	28	7	)	)	PUNCT
ecletica-1329	28	8	and	and	CCONJ
ecletica-1329	28	9	non	non	ADJ
ecletica-1329	28	10	-	-	ADJ
ecletica-1329	28	11	small	small	ADJ
ecletica-1329	28	12	cell	cell	NOUN
ecletica-1329	28	13	lung	lung	NOUN
ecletica-1329	28	14	carcinoma	carcinoma	NOUN
ecletica-1329	28	15	(	(	PUNCT
ecletica-1329	28	16	nsclc	nsclc	NOUN
ecletica-1329	28	17	)	)	PUNCT
ecletica-1329	28	18	are	be	AUX
ecletica-1329	28	19	the	the	DET
ecletica-1329	28	20	two	two	NUM
ecletica-1329	28	21	main	main	ADJ
ecletica-1329	28	22	types	type	NOUN
ecletica-1329	28	23	of	of	ADP
ecletica-1329	28	24	lung	lung	NOUN
ecletica-1329	28	25	cancer	cancer	NOUN
ecletica-1329	28	26	(	(	PUNCT
ecletica-1329	28	27	collins	collins	PROPN
ecletica-1329	28	28	et	et	PROPN
ecletica-1329	28	29	al	al	PROPN
ecletica-1329	28	30	.	.	PROPN
ecletica-1329	28	31	,	,	PUNCT
ecletica-1329	28	32	2007	2007	NUM
ecletica-1329	28	33	)	)	PUNCT
ecletica-1329	28	34	.	.	PUNCT
ecletica-1329	29	1	nsclc	nsclc	NOUN
ecletica-1329	29	2	constitutes	constitute	VERB
ecletica-1329	29	3	85	85	NUM
ecletica-1329	29	4	%	%	NOUN
ecletica-1329	29	5	of	of	ADP
ecletica-1329	29	6	total	total	ADJ
ecletica-1329	29	7	cases	case	NOUN
ecletica-1329	29	8	and	and	CCONJ
ecletica-1329	29	9	40	40	NUM
ecletica-1329	29	10	%	%	NOUN
ecletica-1329	29	11	of	of	ADP
ecletica-1329	29	12	nsclcs	nsclcs	NOUN
ecletica-1329	29	13	are	be	AUX
ecletica-1329	29	14	adenocarcinoma	adenocarcinoma	NOUN
ecletica-1329	29	15	(	(	PUNCT
ecletica-1329	29	16	devesa	devesa	PROPN
ecletica-1329	29	17	et	et	PROPN
ecletica-1329	29	18	al	al	PROPN
ecletica-1329	29	19	.	.	PROPN
ecletica-1329	29	20	,	,	PUNCT
ecletica-1329	29	21	2005	2005	NUM
ecletica-1329	29	22	;	;	PUNCT
ecletica-1329	29	23	morgensztern	morgensztern	PROPN
ecletica-1329	29	24	et	et	PROPN
ecletica-1329	29	25	al	al	PROPN
ecletica-1329	29	26	.	.	PROPN
ecletica-1329	29	27	,	,	PUNCT
ecletica-1329	29	28	2010	2010	NUM
ecletica-1329	29	29	)	)	PUNCT
ecletica-1329	29	30	.	.	PUNCT
ecletica-1329	30	1	the	the	DET
ecletica-1329	30	2	most	most	ADV
ecletica-1329	30	3	effective	effective	ADJ
ecletica-1329	30	4	strategy	strategy	NOUN
ecletica-1329	30	5	to	to	PART
ecletica-1329	30	6	treat	treat	VERB
ecletica-1329	30	7	nsclc	nsclc	NOUN
ecletica-1329	30	8	adenocarcinoma	adenocarcinoma	NOUN
ecletica-1329	30	9	is	be	AUX
ecletica-1329	30	10	to	to	PART
ecletica-1329	30	11	target	target	VERB
ecletica-1329	30	12	the	the	DET
ecletica-1329	30	13	adenosine	adenosine	NOUN
ecletica-1329	30	14	triphosphate	triphosphate	NOUN
ecletica-1329	30	15	(	(	PUNCT
ecletica-1329	30	16	atp	atp	NOUN
ecletica-1329	30	17	)	)	PUNCT
ecletica-1329	30	18	binding	bind	VERB
ecletica-1329	30	19	cleft	cleft	NOUN
ecletica-1329	30	20	of	of	ADP
ecletica-1329	30	21	the	the	DET
ecletica-1329	30	22	tyrosine	tyrosine	NOUN
ecletica-1329	30	23	kinase	kinase	NOUN
ecletica-1329	30	24	binding	bind	VERB
ecletica-1329	30	25	domain	domain	NOUN
ecletica-1329	30	26	of	of	ADP
ecletica-1329	30	27	epidermal	epidermal	ADJ
ecletica-1329	30	28	growth	growth	NOUN
ecletica-1329	30	29	factor	factor	NOUN
ecletica-1329	30	30	receptor	receptor	NOUN
ecletica-1329	30	31	(	(	PUNCT
ecletica-1329	30	32	egfr	egfr	X
ecletica-1329	30	33	)	)	PUNCT
ecletica-1329	30	34	using	use	VERB
ecletica-1329	30	35	possible	possible	ADJ
ecletica-1329	30	36	inhibitors	inhibitor	NOUN
ecletica-1329	30	37	(	(	PUNCT
ecletica-1329	30	38	such	such	ADJ
ecletica-1329	30	39	as	as	ADP
ecletica-1329	30	40	gefitinib	gefitinib	NOUN
ecletica-1329	30	41	and	and	CCONJ
ecletica-1329	30	42	erlotinib	erlotinib	NOUN
ecletica-1329	30	43	)	)	PUNCT
ecletica-1329	30	44	(	(	PUNCT
ecletica-1329	30	45	zhang	zhang	X
ecletica-1329	30	46	et	et	PROPN
ecletica-1329	30	47	al	al	PROPN
ecletica-1329	30	48	.	.	PROPN
ecletica-1329	30	49	,	,	PUNCT
ecletica-1329	30	50	2012	2012	NUM
ecletica-1329	30	51	)	)	PUNCT
ecletica-1329	30	52	.	.	PUNCT
ecletica-1329	31	1	however	however	ADV
ecletica-1329	31	2	,	,	PUNCT
ecletica-1329	31	3	the	the	DET
ecletica-1329	31	4	establishment	establishment	NOUN
ecletica-1329	31	5	of	of	ADP
ecletica-1329	31	6	acquired	acquire	VERB
ecletica-1329	31	7	drug	drug	NOUN
ecletica-1329	31	8	resistance	resistance	NOUN
ecletica-1329	31	9	in	in	ADP
ecletica-1329	31	10	patients	patient	NOUN
ecletica-1329	31	11	restricts	restrict	VERB
ecletica-1329	31	12	its	its	PRON
ecletica-1329	31	13	usage	usage	NOUN
ecletica-1329	31	14	in	in	ADP
ecletica-1329	31	15	therapeutic	therapeutic	ADJ
ecletica-1329	31	16	settings	setting	NOUN
ecletica-1329	31	17	(	(	PUNCT
ecletica-1329	31	18	stella	stella	X
ecletica-1329	31	19	et	et	PROPN
ecletica-1329	31	20	al	al	PROPN
ecletica-1329	31	21	.	.	PROPN
ecletica-1329	31	22	,	,	PUNCT
ecletica-1329	31	23	2012	2012	NUM
ecletica-1329	31	24	)	)	PUNCT
ecletica-1329	31	25	.	.	PUNCT
ecletica-1329	32	1	the	the	DET
ecletica-1329	32	2	underlying	underlie	VERB
ecletica-1329	32	3	molecular	molecular	ADJ
ecletica-1329	32	4	reason	reason	NOUN
ecletica-1329	32	5	of	of	ADP
ecletica-1329	32	6	medication	medication	NOUN
ecletica-1329	32	7	resistance	resistance	NOUN
ecletica-1329	32	8	is	be	AUX
ecletica-1329	32	9	thought	think	VERB
ecletica-1329	32	10	to	to	PART
ecletica-1329	32	11	be	be	AUX
ecletica-1329	32	12	steric	steric	ADJ
ecletica-1329	32	13	interferences	interference	NOUN
ecletica-1329	32	14	in	in	ADP
ecletica-1329	32	15	the	the	DET
ecletica-1329	32	16	egfr	egfr	NOUN
ecletica-1329	32	17	and	and	CCONJ
ecletica-1329	32	18	inhibitor	inhibitor	NOUN
ecletica-1329	32	19	binding	bind	VERB
ecletica-1329	32	20	properties	property	NOUN
ecletica-1329	32	21	caused	cause	VERB
ecletica-1329	32	22	by	by	ADP
ecletica-1329	32	23	mutations	mutation	NOUN
ecletica-1329	32	24	.	.	PUNCT
ecletica-1329	33	1	although	although	SCONJ
ecletica-1329	33	2	irreversible	irreversible	ADJ
ecletica-1329	33	3	inhibitors	inhibitor	NOUN
ecletica-1329	33	4	such	such	ADJ
ecletica-1329	33	5	as	as	ADP
ecletica-1329	33	6	afatinib	afatinib	NOUN
ecletica-1329	33	7	and	and	CCONJ
ecletica-1329	33	8	osimertinib	osimertinib	NOUN
ecletica-1329	33	9	were	be	AUX
ecletica-1329	33	10	created	create	VERB
ecletica-1329	33	11	to	to	PART
ecletica-1329	33	12	combat	combat	VERB
ecletica-1329	33	13	egfr	egfr	ADJ
ecletica-1329	33	14	molecule	molecule	NOUN
ecletica-1329	33	15	acquired	acquire	VERB
ecletica-1329	33	16	resistance	resistance	NOUN
ecletica-1329	33	17	,	,	PUNCT
ecletica-1329	33	18	they	they	PRON
ecletica-1329	33	19	were	be	AUX
ecletica-1329	33	20	discovered	discover	VERB
ecletica-1329	33	21	to	to	PART
ecletica-1329	33	22	change	change	VERB
ecletica-1329	33	23	the	the	DET
ecletica-1329	33	24	covalent	covalent	ADJ
ecletica-1329	33	25	connections	connection	NOUN
ecletica-1329	33	26	in	in	ADP
ecletica-1329	33	27	the	the	DET
ecletica-1329	33	28	egfr	egfr	ADJ
ecletica-1329	33	29	protein	protein	NOUN
ecletica-1329	33	30	structure	structure	NOUN
ecletica-1329	33	31	,	,	PUNCT
ecletica-1329	33	32	restricting	restrict	VERB
ecletica-1329	33	33	their	their	PRON
ecletica-1329	33	34	practical	practical	ADJ
ecletica-1329	33	35	application	application	NOUN
ecletica-1329	33	36	(	(	PUNCT
ecletica-1329	33	37	sato	sato	PROPN
ecletica-1329	33	38	et	et	PROPN
ecletica-1329	33	39	al	al	PROPN
ecletica-1329	33	40	.	.	PROPN
ecletica-1329	33	41	,	,	PUNCT
ecletica-1329	33	42	2012	2012	NUM
ecletica-1329	33	43	)	)	PUNCT
ecletica-1329	33	44	.	.	PUNCT
ecletica-1329	34	1	as	as	ADP
ecletica-1329	34	2	a	a	DET
ecletica-1329	34	3	result	result	NOUN
ecletica-1329	34	4	,	,	PUNCT
ecletica-1329	34	5	there	there	PRON
ecletica-1329	34	6	is	be	VERB
ecletica-1329	34	7	a	a	DET
ecletica-1329	34	8	pressing	press	VERB
ecletica-1329	34	9	need	need	NOUN
ecletica-1329	34	10	to	to	PART
ecletica-1329	34	11	find	find	VERB
ecletica-1329	34	12	and	and	CCONJ
ecletica-1329	34	13	develop	develop	VERB
ecletica-1329	34	14	novel	novel	NOUN
ecletica-1329	34	15	,	,	PUNCT
ecletica-1329	34	16	safe	safe	ADJ
ecletica-1329	34	17	treatment	treatment	NOUN
ecletica-1329	34	18	regimens	regimen	NOUN
ecletica-1329	34	19	that	that	PRON
ecletica-1329	34	20	can	can	AUX
ecletica-1329	34	21	quickly	quickly	ADV
ecletica-1329	34	22	overcome	overcome	VERB
ecletica-1329	34	23	medication	medication	NOUN
ecletica-1329	34	24	resistance	resistance	NOUN
ecletica-1329	34	25	caused	cause	VERB
ecletica-1329	34	26	by	by	ADP
ecletica-1329	34	27	egfr	egfr	ADJ
ecletica-1329	34	28	mutations	mutation	NOUN
ecletica-1329	34	29	.	.	PUNCT
ecletica-1329	35	1	quinolines	quinoline	NOUN
ecletica-1329	35	2	and	and	CCONJ
ecletica-1329	35	3	their	their	PRON
ecletica-1329	35	4	derivatives	derivative	NOUN
ecletica-1329	35	5	are	be	AUX
ecletica-1329	35	6	a	a	DET
ecletica-1329	35	7	class	class	NOUN
ecletica-1329	35	8	of	of	ADP
ecletica-1329	35	9	chemical	chemical	NOUN
ecletica-1329	35	10	compounds	compound	NOUN
ecletica-1329	35	11	that	that	PRON
ecletica-1329	35	12	have	have	AUX
ecletica-1329	35	13	been	be	AUX
ecletica-1329	35	14	shown	show	VERB
ecletica-1329	35	15	to	to	PART
ecletica-1329	35	16	have	have	VERB
ecletica-1329	35	17	a	a	DET
ecletica-1329	35	18	variety	variety	NOUN
ecletica-1329	35	19	of	of	ADP
ecletica-1329	35	20	biological	biological	ADJ
ecletica-1329	35	21	actions	action	NOUN
ecletica-1329	35	22	,	,	PUNCT
ecletica-1329	35	23	including	include	VERB
ecletica-1329	35	24	anticancer	anticancer	NOUN
ecletica-1329	35	25	activity	activity	NOUN
ecletica-1329	35	26	(	(	PUNCT
ecletica-1329	35	27	hayat	hayat	X
ecletica-1329	35	28	et	et	PROPN
ecletica-1329	35	29	al	al	PROPN
ecletica-1329	35	30	.	.	PROPN
ecletica-1329	35	31	,	,	PUNCT
ecletica-1329	35	32	2010	2010	NUM
ecletica-1329	35	33	;	;	PUNCT
ecletica-1329	35	34	mekheimer	mekheimer	PROPN
ecletica-1329	35	35	et	et	PROPN
ecletica-1329	35	36	al	al	PROPN
ecletica-1329	35	37	.	.	PROPN
ecletica-1329	35	38	,	,	PUNCT
ecletica-1329	35	39	2020	2020	NUM
ecletica-1329	35	40	)	)	PUNCT
ecletica-1329	35	41	.	.	PUNCT
ecletica-1329	36	1	tetrahydroquinolines	tetrahydroquinoline	NOUN
ecletica-1329	36	2	are	be	AUX
ecletica-1329	36	3	significant	significant	ADJ
ecletica-1329	36	4	building	building	NOUN
ecletica-1329	36	5	blocks	block	NOUN
ecletica-1329	36	6	in	in	ADP
ecletica-1329	36	7	the	the	DET
ecletica-1329	36	8	chemical	chemical	NOUN
ecletica-1329	36	9	structure	structure	NOUN
ecletica-1329	36	10	of	of	ADP
ecletica-1329	36	11	a	a	DET
ecletica-1329	36	12	variety	variety	NOUN
ecletica-1329	36	13	of	of	ADP
ecletica-1329	36	14	physiologically	physiologically	ADV
ecletica-1329	36	15	active	active	ADJ
ecletica-1329	36	16	derivatives	derivative	NOUN
ecletica-1329	36	17	,	,	PUNCT
ecletica-1329	36	18	such	such	ADJ
ecletica-1329	36	19	as	as	ADP
ecletica-1329	36	20	pyrazolo[3,4	pyrazolo[3,4	NOUN
ecletica-1329	36	21	-	-	SYM
ecletica-1329	36	22	b]quinolines	b]quinoline	NOUN
ecletica-1329	36	23	,	,	PUNCT
ecletica-1329	36	24	and	and	CCONJ
ecletica-1329	36	25	have	have	VERB
ecletica-1329	36	26	strong	strong	ADJ
ecletica-1329	36	27	anticancer	anticancer	NOUN
ecletica-1329	36	28	properties	property	NOUN
ecletica-1329	36	29	(	(	PUNCT
ecletica-1329	36	30	faidallah	faidallah	ADJ
ecletica-1329	36	31	and	and	CCONJ
ecletica-1329	36	32	rostomb	rostomb	NOUN
ecletica-1329	36	33	,	,	PUNCT
ecletica-1329	36	34	2013	2013	NUM
ecletica-1329	36	35	)	)	PUNCT
ecletica-1329	36	36	.	.	PUNCT
ecletica-1329	37	1	the	the	DET
ecletica-1329	37	2	quinoline	quinoline	NOUN
ecletica-1329	37	3	and	and	CCONJ
ecletica-1329	37	4	pyrazole	pyrazole	NOUN
ecletica-1329	37	5	moieties	moiety	NOUN
ecletica-1329	37	6	in	in	ADP
ecletica-1329	37	7	the	the	DET
ecletica-1329	37	8	pyrazoloquinolines	pyrazoloquinoline	NOUN
ecletica-1329	37	9	framework	framework	NOUN
ecletica-1329	37	10	are	be	AUX
ecletica-1329	37	11	excellent	excellent	ADJ
ecletica-1329	37	12	anticancer	anticancer	NOUN
ecletica-1329	37	13	medicines	medicine	NOUN
ecletica-1329	37	14	with	with	ADP
ecletica-1329	37	15	a	a	DET
ecletica-1329	37	16	wide	wide	ADJ
ecletica-1329	37	17	range	range	NOUN
ecletica-1329	37	18	of	of	ADP
ecletica-1329	37	19	pharmacological	pharmacological	ADJ
ecletica-1329	37	20	efficacies	efficacy	NOUN
ecletica-1329	37	21	(	(	PUNCT
ecletica-1329	37	22	opoku	opoku	NOUN
ecletica-1329	37	23	-	-	PUNCT
ecletica-1329	37	24	temeng	temeng	NOUN
ecletica-1329	37	25	et	et	PROPN
ecletica-1329	37	26	al	al	PROPN
ecletica-1329	37	27	.	.	PROPN
ecletica-1329	37	28	,	,	PUNCT
ecletica-1329	37	29	2018	2018	NUM
ecletica-1329	37	30	)	)	PUNCT
ecletica-1329	37	31	.	.	PUNCT
ecletica-1329	38	1	in	in	ADP
ecletica-1329	38	2	the	the	DET
ecletica-1329	38	3	creation	creation	NOUN
ecletica-1329	38	4	of	of	ADP
ecletica-1329	38	5	anticancer	anticancer	NOUN
ecletica-1329	38	6	medicines	medicine	NOUN
ecletica-1329	38	7	,	,	PUNCT
ecletica-1329	38	8	the	the	DET
ecletica-1329	38	9	quinoline	quinoline	NOUN
ecletica-1329	38	10	hydrazide	hydrazide	ADV
ecletica-1329	38	11	scaffold	scaffold	NOUN
ecletica-1329	38	12	plays	play	VERB
ecletica-1329	38	13	a	a	DET
ecletica-1329	38	14	significant	significant	ADJ
ecletica-1329	38	15	role	role	NOUN
ecletica-1329	38	16	(	(	PUNCT
ecletica-1329	38	17	mandewale	mandewale	NOUN
ecletica-1329	38	18	et	et	PROPN
ecletica-1329	38	19	al	al	PROPN
ecletica-1329	38	20	.	.	PROPN
ecletica-1329	38	21	,	,	PUNCT
ecletica-1329	38	22	2017	2017	NUM
ecletica-1329	38	23	)	)	PUNCT
ecletica-1329	38	24	.	.	PUNCT
ecletica-1329	39	1	currently	currently	ADV
ecletica-1329	39	2	,	,	PUNCT
ecletica-1329	39	3	there	there	PRON
ecletica-1329	39	4	is	be	VERB
ecletica-1329	39	5	a	a	DET
ecletica-1329	39	6	lot	lot	NOUN
ecletica-1329	39	7	of	of	ADP
ecletica-1329	39	8	interest	interest	NOUN
ecletica-1329	39	9	in	in	ADP
ecletica-1329	39	10	pyrazoloquinolines	pyrazoloquinoline	NOUN
ecletica-1329	39	11	framework	framework	VERB
ecletica-1329	39	12	physiologically	physiologically	ADV
ecletica-1329	39	13	active	active	ADJ
ecletica-1329	39	14	molecules	molecule	NOUN
ecletica-1329	39	15	.	.	PUNCT
ecletica-1329	40	1	computational	computational	ADJ
ecletica-1329	40	2	studies	study	NOUN
ecletica-1329	40	3	based	base	VERB
ecletica-1329	40	4	on	on	ADP
ecletica-1329	40	5	ligand	ligand	NOUN
ecletica-1329	40	6	and	and	CCONJ
ecletica-1329	40	7	structurebased	structurebase	VERB
ecletica-1329	40	8	techniques	technique	NOUN
ecletica-1329	40	9	are	be	AUX
ecletica-1329	40	10	regarded	regard	VERB
ecletica-1329	40	11	useful	useful	ADJ
ecletica-1329	40	12	tools	tool	NOUN
ecletica-1329	40	13	in	in	ADP
ecletica-1329	40	14	medicinal	medicinal	ADJ
ecletica-1329	40	15	chemistry	chemistry	NOUN
ecletica-1329	40	16	for	for	ADP
ecletica-1329	40	17	speeding	speed	VERB
ecletica-1329	40	18	up	up	ADP
ecletica-1329	40	19	the	the	DET
ecletica-1329	40	20	drug	drug	NOUN
ecletica-1329	40	21	design	design	NOUN
ecletica-1329	40	22	process	process	NOUN
ecletica-1329	40	23	.	.	PUNCT
ecletica-1329	41	1	molecular	molecular	ADJ
ecletica-1329	41	2	docking	docking	NOUN
ecletica-1329	41	3	is	be	AUX
ecletica-1329	41	4	a	a	DET
ecletica-1329	41	5	computer	computer	NOUN
ecletica-1329	41	6	-	-	PUNCT
ecletica-1329	41	7	aided	aid	VERB
ecletica-1329	41	8	drug	drug	NOUN
ecletica-1329	41	9	design	design	NOUN
ecletica-1329	41	10	process	process	NOUN
ecletica-1329	41	11	that	that	PRON
ecletica-1329	41	12	uses	use	VERB
ecletica-1329	41	13	in	in	ADP
ecletica-1329	41	14	silico	silico	NOUN
ecletica-1329	41	15	virtual	virtual	ADJ
ecletica-1329	41	16	screening	screening	NOUN
ecletica-1329	41	17	to	to	PART
ecletica-1329	41	18	determine	determine	VERB
ecletica-1329	41	19	how	how	SCONJ
ecletica-1329	41	20	ligands	ligand	NOUN
ecletica-1329	41	21	and	and	CCONJ
ecletica-1329	41	22	receptors	receptor	NOUN
ecletica-1329	41	23	interact	interact	VERB
ecletica-1329	41	24	utilizing	utilize	VERB
ecletica-1329	41	25	their	their	PRON
ecletica-1329	41	26	specific	specific	ADJ
ecletica-1329	41	27	3d	3d	NOUN
ecletica-1329	41	28	architectures	architecture	NOUN
ecletica-1329	41	29	(	(	PUNCT
ecletica-1329	41	30	lapa	lapa	X
ecletica-1329	41	31	et	et	PROPN
ecletica-1329	41	32	al	al	PROPN
ecletica-1329	41	33	.	.	PROPN
ecletica-1329	41	34	,	,	PUNCT
ecletica-1329	41	35	2013	2013	NUM
ecletica-1329	41	36	)	)	PUNCT
ecletica-1329	41	37	.	.	PUNCT
ecletica-1329	42	1	a	a	DET
ecletica-1329	42	2	drug	drug	NOUN
ecletica-1329	42	3	’s	’s	PART
ecletica-1329	42	4	druglikeness	druglikeness	NOUN
ecletica-1329	42	5	,	,	PUNCT
ecletica-1329	42	6	lipophilicity	lipophilicity	NOUN
ecletica-1329	42	7	,	,	PUNCT
ecletica-1329	42	8	pharmacokinetic	pharmacokinetic	ADJ
ecletica-1329	42	9	,	,	PUNCT
ecletica-1329	42	10	and	and	CCONJ
ecletica-1329	42	11	toxicity	toxicity	NOUN
ecletica-1329	42	12	qualities	quality	NOUN
ecletica-1329	42	13	provide	provide	VERB
ecletica-1329	42	14	information	information	NOUN
ecletica-1329	42	15	about	about	ADP
ecletica-1329	42	16	how	how	SCONJ
ecletica-1329	42	17	the	the	DET
ecletica-1329	42	18	body	body	NOUN
ecletica-1329	42	19	reacts	react	VERB
ecletica-1329	42	20	to	to	ADP
ecletica-1329	42	21	its	its	PRON
ecletica-1329	42	22	administration	administration	NOUN
ecletica-1329	42	23	.	.	PUNCT
ecletica-1329	43	1	as	as	ADP
ecletica-1329	43	2	a	a	DET
ecletica-1329	43	3	result	result	NOUN
ecletica-1329	43	4	,	,	PUNCT
ecletica-1329	43	5	before	before	SCONJ
ecletica-1329	43	6	this	this	DET
ecletica-1329	43	7	medicine	medicine	NOUN
ecletica-1329	43	8	reaches	reach	VERB
ecletica-1329	43	9	the	the	DET
ecletica-1329	43	10	final	final	ADJ
ecletica-1329	43	11	(	(	PUNCT
ecletica-1329	43	12	clinical	clinical	ADJ
ecletica-1329	43	13	)	)	PUNCT
ecletica-1329	43	14	stage	stage	NOUN
ecletica-1329	43	15	,	,	PUNCT
ecletica-1329	43	16	it	it	PRON
ecletica-1329	43	17	must	must	AUX
ecletica-1329	43	18	be	be	AUX
ecletica-1329	43	19	studied	study	VERB
ecletica-1329	43	20	for	for	ADP
ecletica-1329	43	21	drug	drug	NOUN
ecletica-1329	43	22	-	-	PUNCT
ecletica-1329	43	23	likeness	likeness	NOUN
ecletica-1329	43	24	and	and	CCONJ
ecletica-1329	43	25	pharmacokinetic	pharmacokinetic	ADJ
ecletica-1329	43	26	features	feature	NOUN
ecletica-1329	43	27	.	.	PUNCT
ecletica-1329	44	1	therefore	therefore	ADV
ecletica-1329	44	2	,	,	PUNCT
ecletica-1329	44	3	this	this	DET
ecletica-1329	44	4	research	research	NOUN
ecletica-1329	44	5	was	be	AUX
ecletica-1329	44	6	aimed	aim	VERB
ecletica-1329	44	7	at	at	ADP
ecletica-1329	44	8	identifying	identify	VERB
ecletica-1329	44	9	the	the	DET
ecletica-1329	44	10	descriptors	descriptor	NOUN
ecletica-1329	44	11	that	that	PRON
ecletica-1329	44	12	are	be	AUX
ecletica-1329	44	13	responsible	responsible	ADJ
ecletica-1329	44	14	for	for	ADP
ecletica-1329	44	15	anti	anti	ADJ
ecletica-1329	44	16	-	-	ADJ
ecletica-1329	44	17	egfr	egfr	ADJ
ecletica-1329	44	18	activities	activity	NOUN
ecletica-1329	44	19	thereby	thereby	ADV
ecletica-1329	44	20	downregulating	downregulate	VERB
ecletica-1329	44	21	human	human	ADJ
ecletica-1329	44	22	lung	lung	NOUN
ecletica-1329	44	23	cancer	cancer	NOUN
ecletica-1329	44	24	and	and	CCONJ
ecletica-1329	44	25	developing	develop	VERB
ecletica-1329	44	26	valid	valid	ADJ
ecletica-1329	44	27	quantitative	quantitative	ADJ
ecletica-1329	44	28	structural	structural	ADJ
ecletica-1329	44	29	relationship	relationship	NOUN
ecletica-1329	44	30	activity	activity	NOUN
ecletica-1329	44	31	(	(	PUNCT
ecletica-1329	44	32	qsar	qsar	NOUN
ecletica-1329	44	33	)	)	PUNCT
ecletica-1329	44	34	model	model	NOUN
ecletica-1329	44	35	using	use	VERB
ecletica-1329	44	36	the	the	DET
ecletica-1329	44	37	obtained	obtain	VERB
ecletica-1329	44	38	descriptors	descriptor	NOUN
ecletica-1329	44	39	as	as	ADV
ecletica-1329	44	40	well	well	ADV
ecletica-1329	44	41	as	as	ADP
ecletica-1329	44	42	observing	observe	VERB
ecletica-1329	44	43	the	the	DET
ecletica-1329	44	44	nonbonding	nonbonding	NOUN
ecletica-1329	44	45	interactions	interaction	NOUN
ecletica-1329	44	46	between	between	ADP
ecletica-1329	44	47	the	the	DET
ecletica-1329	44	48	selected	select	VERB
ecletica-1329	44	49	phytochemicals	phytochemical	NOUN
ecletica-1329	44	50	(	(	PUNCT
ecletica-1329	44	51	synthesized	synthesize	VERB
ecletica-1329	44	52	by	by	ADP
ecletica-1329	44	53	fathy	fathy	PROPN
ecletica-1329	44	54	et	et	PROPN
ecletica-1329	44	55	al	al	PROPN
ecletica-1329	44	56	.	.	PROPN
ecletica-1329	44	57	,	,	PUNCT
ecletica-1329	44	58	2020	2020	NUM
ecletica-1329	44	59	)	)	PUNCT
ecletica-1329	44	60	and	and	CCONJ
ecletica-1329	44	61	egfr	egfr	NOUN
ecletica-1329	44	62	(	(	PUNCT
ecletica-1329	44	63	pdb	pdb	PROPN
ecletica-1329	44	64	i	i	NOUN
ecletica-1329	44	65	d	d	PROPN
ecletica-1329	44	66	:	:	PUNCT
ecletica-1329	44	67	4lrm	4lrm	NUM
ecletica-1329	44	68	)	)	PUNCT
ecletica-1329	44	69	(	(	PUNCT
ecletica-1329	44	70	yasuda	yasuda	NOUN
ecletica-1329	44	71	et	et	PROPN
ecletica-1329	44	72	al	al	PROPN
ecletica-1329	44	73	.	.	PROPN
ecletica-1329	44	74	,	,	PUNCT
ecletica-1329	44	75	2013	2013	NUM
ecletica-1329	44	76	)	)	PUNCT
ecletica-1329	44	77	.	.	PUNCT
ecletica-1329	45	1	2	2	X
ecletica-1329	45	2	.	.	X
ecletica-1329	45	3	methodology	methodology	NOUN
ecletica-1329	45	4	2.1	2.1	NUM
ecletica-1329	45	5	quantum	quantum	NOUN
ecletica-1329	45	6	chemical	chemical	NOUN
ecletica-1329	45	7	study	study	NOUN
ecletica-1329	45	8	for	for	ADP
ecletica-1329	45	9	this	this	DET
ecletica-1329	45	10	study	study	NOUN
ecletica-1329	45	11	,	,	PUNCT
ecletica-1329	45	12	a	a	DET
ecletica-1329	45	13	set	set	NOUN
ecletica-1329	45	14	of	of	ADP
ecletica-1329	45	15	14	14	NUM
ecletica-1329	45	16	tetrahydroquinoline	tetrahydroquinoline	ADJ
ecletica-1329	45	17	derivatives	derivative	NOUN
ecletica-1329	45	18	obtained	obtain	VERB
ecletica-1329	45	19	from	from	ADP
ecletica-1329	45	20	fathy	fathy	PROPN
ecletica-1329	45	21	et	et	PROPN
ecletica-1329	45	22	al	al	PROPN
ecletica-1329	45	23	.	.	PROPN
ecletica-1329	45	24	(	(	PUNCT
ecletica-1329	45	25	2020	2020	NUM
ecletica-1329	45	26	)	)	PUNCT
ecletica-1329	45	27	as	as	ADP
ecletica-1329	45	28	potential	potential	ADJ
ecletica-1329	45	29	anti	anti	ADJ
ecletica-1329	45	30	-	-	ADJ
ecletica-1329	45	31	egfr	egfr	ADJ
ecletica-1329	45	32	agents	agent	NOUN
ecletica-1329	45	33	with	with	ADP
ecletica-1329	45	34	inhibitory	inhibitory	ADJ
ecletica-1329	45	35	activities	activity	NOUN
ecletica-1329	45	36	(	(	PUNCT
ecletica-1329	45	37	ic50	ic50	PROPN
ecletica-1329	45	38	)	)	PUNCT
ecletica-1329	45	39	in	in	ADP
ecletica-1329	45	40	μmol	μmol	PROPN
ecletica-1329	45	41	l–1	l–1	NOUN
ecletica-1329	45	42	(	(	PUNCT
ecletica-1329	45	43	table	table	NOUN
ecletica-1329	45	44	1	1	NUM
ecletica-1329	45	45	)	)	PUNCT
ecletica-1329	45	46	was	be	AUX
ecletica-1329	45	47	investigated	investigate	VERB
ecletica-1329	45	48	.	.	PUNCT
ecletica-1329	46	1	all	all	DET
ecletica-1329	46	2	the	the	DET
ecletica-1329	46	3	studied	study	VERB
ecletica-1329	46	4	compounds	compound	NOUN
ecletica-1329	46	5	were	be	AUX
ecletica-1329	46	6	optimized	optimize	VERB
ecletica-1329	46	7	using	use	VERB
ecletica-1329	46	8	spartan	spartan	ADJ
ecletica-1329	46	9	14	14	NUM
ecletica-1329	46	10	software	software	NOUN
ecletica-1329	46	11	(	(	PUNCT
ecletica-1329	46	12	waziri	waziri	PROPN
ecletica-1329	46	13	et	et	PROPN
ecletica-1329	46	14	al	al	PROPN
ecletica-1329	46	15	.	.	PROPN
ecletica-1329	46	16	,	,	PUNCT
ecletica-1329	46	17	2023	2023	NUM
ecletica-1329	46	18	)	)	PUNCT
ecletica-1329	46	19	to	to	PART
ecletica-1329	46	20	achieve	achieve	VERB
ecletica-1329	46	21	a	a	DET
ecletica-1329	46	22	stable	stable	ADJ
ecletica-1329	46	23	conformation	conformation	NOUN
ecletica-1329	46	24	with	with	ADP
ecletica-1329	46	25	the	the	DET
ecletica-1329	46	26	least	least	ADJ
ecletica-1329	46	27	amount	amount	NOUN
ecletica-1329	46	28	of	of	ADP
ecletica-1329	46	29	energy	energy	NOUN
ecletica-1329	46	30	.	.	PUNCT
ecletica-1329	47	1	molecular	molecular	ADJ
ecletica-1329	47	2	mechanics	mechanic	NOUN
ecletica-1329	47	3	force	force	NOUN
ecletica-1329	47	4	field	field	NOUN
ecletica-1329	47	5	(	(	PUNCT
ecletica-1329	47	6	vanommeslaeghe	vanommeslaeghe	NOUN
ecletica-1329	47	7	et	et	PROPN
ecletica-1329	47	8	al	al	PROPN
ecletica-1329	47	9	.	.	PROPN
ecletica-1329	47	10	,	,	PUNCT
ecletica-1329	47	11	2014	2014	NUM
ecletica-1329	47	12	)	)	PUNCT
ecletica-1329	47	13	was	be	AUX
ecletica-1329	47	14	used	use	VERB
ecletica-1329	47	15	to	to	PART
ecletica-1329	47	16	remove	remove	VERB
ecletica-1329	47	17	the	the	DET
ecletica-1329	47	18	strain	strain	NOUN
ecletica-1329	47	19	energy	energy	NOUN
ecletica-1329	47	20	from	from	ADP
ecletica-1329	47	21	the	the	DET
ecletica-1329	47	22	molecules	molecule	NOUN
ecletica-1329	47	23	,	,	PUNCT
ecletica-1329	47	24	and	and	CCONJ
ecletica-1329	47	25	density	density	NOUN
ecletica-1329	47	26	functional	functional	ADJ
ecletica-1329	47	27	theory	theory	NOUN
ecletica-1329	47	28	was	be	AUX
ecletica-1329	47	29	used	use	VERB
ecletica-1329	47	30	to	to	PART
ecletica-1329	47	31	execute	execute	VERB
ecletica-1329	47	32	the	the	DET
ecletica-1329	47	33	optimization	optimization	NOUN
ecletica-1329	47	34	using	use	VERB
ecletica-1329	47	35	the	the	DET
ecletica-1329	47	36	standard	standard	ADJ
ecletica-1329	47	37	6	6	NUM
ecletica-1329	47	38	-	-	PUNCT
ecletica-1329	47	39	31+g	31+g	NUM
ecletica-1329	47	40	*	*	PUNCT
ecletica-1329	47	41	(	(	PUNCT
ecletica-1329	47	42	d	d	NOUN
ecletica-1329	47	43	,	,	PUNCT
ecletica-1329	47	44	p	p	NOUN
ecletica-1329	47	45	)	)	PUNCT
ecletica-1329	47	46	basis	basis	NOUN
ecletica-1329	47	47	set	set	NOUN
ecletica-1329	47	48	,	,	PUNCT
ecletica-1329	47	49	which	which	PRON
ecletica-1329	47	50	includes	include	VERB
ecletica-1329	47	51	becke	becke	NOUN
ecletica-1329	47	52	’s	’s	PART
ecletica-1329	47	53	(	(	PUNCT
ecletica-1329	47	54	1993	1993	NUM
ecletica-1329	47	55	)	)	PUNCT
ecletica-1329	47	56	gradient	gradient	NOUN
ecletica-1329	47	57	,	,	PUNCT
ecletica-1329	47	58	exchange	exchange	NOUN
ecletica-1329	47	59	correlation	correlation	NOUN
ecletica-1329	47	60	and	and	CCONJ
ecletica-1329	47	61	the	the	DET
ecletica-1329	47	62	yang	yang	PROPN
ecletica-1329	47	63	et	et	PROPN
ecletica-1329	47	64	al	al	PROPN
ecletica-1329	47	65	.	.	PROPN
ecletica-1329	48	1	(	(	PUNCT
ecletica-1329	48	2	2005	2005	NUM
ecletica-1329	48	3	)	)	PUNCT
ecletica-1329	48	4	,	,	PUNCT
ecletica-1329	48	5	parr	parr	PROPN
ecletica-1329	48	6	et	et	PROPN
ecletica-1329	48	7	al	al	PROPN
ecletica-1329	48	8	.	.	PROPN
ecletica-1329	49	1	(	(	PUNCT
ecletica-1329	49	2	1999	1999	NUM
ecletica-1329	49	3	)	)	PUNCT
ecletica-1329	49	4	correlation	correlation	NOUN
ecletica-1329	49	5	functional	functional	ADJ
ecletica-1329	49	6	(	(	PUNCT
ecletica-1329	49	7	i.e.	i.e.	X
ecletica-1329	49	8	,	,	PUNCT
ecletica-1329	49	9	b3lyp	b3lyp	NUM
ecletica-1329	49	10	)	)	PUNCT
ecletica-1329	49	11	.	.	PUNCT
ecletica-1329	50	1	https://revista.iq.unesp.br/index.php/ecletica	https://revista.iq.unesp.br/index.php/ecletica	PROPN
ecletica-1329	50	2	https://doi.org/10.26850/1678-4618eqj.v48.1.2023.p55-71	https://doi.org/10.26850/1678-4618eqj.v48.1.2023.p55-71	PROPN
ecletica-1329	50	3	original	original	ADJ
ecletica-1329	50	4	article	article	NOUN
ecletica-1329	50	5	revista.iq.unesp.br	revista.iq.unesp.br	PROPN
ecletica-1329	50	6	57	57	NUM
ecletica-1329	50	7	eclética	eclética	PROPN
ecletica-1329	50	8	química	química	PROPN
ecletica-1329	50	9	,	,	PUNCT
ecletica-1329	50	10	vol	vol	NOUN
ecletica-1329	50	11	.	.	PROPN
ecletica-1329	50	12	48	48	NUM
ecletica-1329	50	13	,	,	PUNCT
ecletica-1329	50	14	n.	n.	NOUN
ecletica-1329	50	15	1	1	NUM
ecletica-1329	50	16	,	,	PUNCT
ecletica-1329	50	17	2023	2023	NUM
ecletica-1329	50	18	,	,	PUNCT
ecletica-1329	50	19	55	55	NUM
ecletica-1329	50	20	-	-	SYM
ecletica-1329	50	21	71	71	NUM
ecletica-1329	50	22	issn	issn	NOUN
ecletica-1329	50	23	:	:	PUNCT
ecletica-1329	50	24	1678	1678	NUM
ecletica-1329	50	25	-	-	SYM
ecletica-1329	50	26	4618	4618	NUM
ecletica-1329	50	27	doi	doi	NOUN
ecletica-1329	50	28	:	:	PUNCT
ecletica-1329	50	29	10.26850/1678	10.26850/1678	NUM
ecletica-1329	50	30	-	-	PUNCT
ecletica-1329	50	31	4618eqj.v48.1.2023.p55	4618eqj.v48.1.2023.p55	NUM
ecletica-1329	50	32	-	-	PUNCT
ecletica-1329	50	33	71	71	NUM
ecletica-1329	50	34	table	table	NOUN
ecletica-1329	50	35	1	1	NUM
ecletica-1329	50	36	.	.	PUNCT
ecletica-1329	50	37	chemical	chemical	ADJ
ecletica-1329	50	38	structure	structure	NOUN
ecletica-1329	50	39	,	,	PUNCT
ecletica-1329	50	40	iupac	iupac	PROPN
ecletica-1329	50	41	name	name	NOUN
ecletica-1329	50	42	and	and	CCONJ
ecletica-1329	50	43	ic50	ic50	PROPN
ecletica-1329	50	44	of	of	ADP
ecletica-1329	50	45	studied	study	VERB
ecletica-1329	50	46	compounds	compound	NOUN
ecletica-1329	50	47	.	.	PUNCT
ecletica-1329	51	1	code	code	NOUN
ecletica-1329	51	2	chemical	chemical	NOUN
ecletica-1329	51	3	structure	structure	NOUN
ecletica-1329	51	4	iupac	iupac	PROPN
ecletica-1329	51	5	name	name	NOUN
ecletica-1329	51	6	ic50	ic50	PROPN
ecletica-1329	51	7	(	(	PUNCT
ecletica-1329	51	8	μmol	μmol	PROPN
ecletica-1329	51	9	l–1	l–1	PROPN
ecletica-1329	51	10	)	)	PUNCT
ecletica-1329	51	11	c1	c1	NOUN
ecletica-1329	51	12	2	2	NUM
ecletica-1329	51	13	-	-	PUNCT
ecletica-1329	51	14	chloro-4-(3,4	chloro-4-(3,4	NUM
ecletica-1329	51	15	-	-	PUNCT
ecletica-1329	51	16	dimethoxyphenyl)5,6,7,8tetrahydroquinoline-3	dimethoxyphenyl)5,6,7,8tetrahydroquinoline-3	NOUN
ecletica-1329	51	17	-	-	PUNCT
ecletica-1329	51	18	car	car	NOUN
ecletica-1329	51	19	-	-	PUNCT
ecletica-1329	51	20	bonitrile	bonitrile	NOUN
ecletica-1329	51	21	85.50	85.50	NUM
ecletica-1329	51	22	c2	c2	PROPN
ecletica-1329	51	23	4-(3,4	4-(3,4	PROPN
ecletica-1329	51	24	-	-	PUNCT
ecletica-1329	51	25	dimethoxyphenyl)-5,6,7,8	dimethoxyphenyl)-5,6,7,8	NOUN
ecletica-1329	51	26	-	-	PUNCT
ecletica-1329	51	27	tetra	tetra	NOUN
ecletica-1329	51	28	-	-	PUNCT
ecletica-1329	51	29	hydro-2hpyrazolo[3,4	hydro-2hpyrazolo[3,4	ADJ
ecletica-1329	51	30	-	-	PUNCT
ecletica-1329	51	31	b]quinolin-3	b]quinolin-3	NOUN
ecletica-1329	51	32	-	-	PUNCT
ecletica-1329	51	33	amine	amine	ADJ
ecletica-1329	51	34	58.60	58.60	NUM
ecletica-1329	51	35	c3	c3	NOUN
ecletica-1329	51	36	(	(	PUNCT
ecletica-1329	51	37	e)-4-(3,4	e)-4-(3,4	ADJ
ecletica-1329	51	38	-	-	PUNCT
ecletica-1329	51	39	dimethoxyphenyl)-n-(4(dimethylamino)benzylidene)-5,6,7,8	dimethoxyphenyl)-n-(4(dimethylamino)benzylidene)-5,6,7,8	NOUN
ecletica-1329	51	40	-	-	PUNCT
ecletica-1329	51	41	tetra	tetra	NOUN
ecletica-1329	51	42	-	-	PUNCT
ecletica-1329	51	43	hydro1h	hydro1h	NOUN
ecletica-1329	51	44	-	-	PUNCT
ecletica-1329	51	45	pyrazolo[3,4	pyrazolo[3,4	PROPN
ecletica-1329	51	46	-	-	PUNCT
ecletica-1329	51	47	b]quinolin-3	b]quinolin-3	NOUN
ecletica-1329	51	48	-	-	PUNCT
ecletica-1329	51	49	amine	amine	ADJ
ecletica-1329	51	50	17.90	17.90	NUM
ecletica-1329	51	51	c4	c4	NOUN
ecletica-1329	51	52	(	(	PUNCT
ecletica-1329	51	53	e)-n-(2,4	e)-n-(2,4	NOUN
ecletica-1329	51	54	-	-	PUNCT
ecletica-1329	51	55	dichlorobenzylidene)-4-(3,4dimethoxyphenyl)-5,6,7,8	dichlorobenzylidene)-4-(3,4dimethoxyphenyl)-5,6,7,8	NOUN
ecletica-1329	51	56	-	-	PUNCT
ecletica-1329	51	57	tetra	tetra	NOUN
ecletica-1329	51	58	hydro-1hpyrazolo[3,4	hydro-1hpyrazolo[3,4	ADJ
ecletica-1329	51	59	-	-	PUNCT
ecletica-1329	51	60	b]quinolin-3	b]quinolin-3	NOUN
ecletica-1329	51	61	-	-	PUNCT
ecletica-1329	51	62	amine	amine	ADJ
ecletica-1329	51	63	35.40	35.40	NUM
ecletica-1329	51	64	c5	c5	PROPN
ecletica-1329	51	65	(	(	PUNCT
ecletica-1329	51	66	e)-4-(3,4	e)-4-(3,4	ADJ
ecletica-1329	51	67	-	-	PUNCT
ecletica-1329	51	68	dimethoxyphenyl)-n-(3methylbenzylidene)-5,6,7,8	dimethoxyphenyl)-n-(3methylbenzylidene)-5,6,7,8	NOUN
ecletica-1329	51	69	-	-	PUNCT
ecletica-1329	51	70	tetrahydro-1hpyrazolo[3,4	tetrahydro-1hpyrazolo[3,4	NOUN
ecletica-1329	51	71	-	-	PUNCT
ecletica-1329	51	72	b]quinolin-3	b]quinolin-3	NOUN
ecletica-1329	51	73	-	-	PUNCT
ecletica-1329	51	74	amine	amine	ADJ
ecletica-1329	51	75	15.40	15.40	NUM
ecletica-1329	51	76	continue	continue	NOUN
ecletica-1329	51	77	…	…	PUNCT
ecletica-1329	51	78	https://revista.iq.unesp.br/index.php/ecletica	https://revista.iq.unesp.br/index.php/ecletica	PROPN
ecletica-1329	51	79	https://doi.org/10.26850/1678-4618eqj.v48.1.2023.p55-71	https://doi.org/10.26850/1678-4618eqj.v48.1.2023.p55-71	PROPN
ecletica-1329	51	80	original	original	ADJ
ecletica-1329	51	81	article	article	NOUN
ecletica-1329	51	82	revista.iq.unesp.br	revista.iq.unesp.br	PROPN
ecletica-1329	51	83	58	58	NUM
ecletica-1329	51	84	eclética	eclética	PROPN
ecletica-1329	51	85	química	química	PROPN
ecletica-1329	51	86	,	,	PUNCT
ecletica-1329	51	87	vol	vol	NOUN
ecletica-1329	51	88	.	.	PROPN
ecletica-1329	51	89	48	48	NUM
ecletica-1329	51	90	,	,	PUNCT
ecletica-1329	51	91	n.	n.	NOUN
ecletica-1329	51	92	1	1	NUM
ecletica-1329	51	93	,	,	PUNCT
ecletica-1329	51	94	2023	2023	NUM
ecletica-1329	51	95	,	,	PUNCT
ecletica-1329	51	96	55	55	NUM
ecletica-1329	51	97	-	-	SYM
ecletica-1329	51	98	71	71	NUM
ecletica-1329	51	99	issn	issn	NOUN
ecletica-1329	51	100	:	:	PUNCT
ecletica-1329	51	101	1678	1678	NUM
ecletica-1329	51	102	-	-	SYM
ecletica-1329	51	103	4618	4618	NUM
ecletica-1329	51	104	doi	doi	NOUN
ecletica-1329	51	105	:	:	PUNCT
ecletica-1329	51	106	10.26850/1678	10.26850/1678	NUM
ecletica-1329	51	107	-	-	PUNCT
ecletica-1329	51	108	4618eqj.v48.1.2023.p55	4618eqj.v48.1.2023.p55	NUM
ecletica-1329	51	109	-	-	PUNCT
ecletica-1329	51	110	71	71	NUM
ecletica-1329	51	111	c6	c6	NOUN
ecletica-1329	51	112	(	(	PUNCT
ecletica-1329	51	113	z)-3-((4-(3,4	z)-3-((4-(3,4	ADJ
ecletica-1329	51	114	-	-	ADJ
ecletica-1329	51	115	dimethoxyphenyl)-5,6,7,8tetrahydro-1h	dimethoxyphenyl)-5,6,7,8tetrahydro-1h	ADJ
ecletica-1329	51	116	-	-	PUNCT
ecletica-1329	51	117	pyrazolo[3,4	pyrazolo[3,4	ADJ
ecletica-1329	51	118	-	-	PUNCT
ecletica-1329	51	119	b]quinoline-3yl)imino)indolin-2	b]quinoline-3yl)imino)indolin-2	NOUN
ecletica-1329	51	120	-	-	PUNCT
ecletica-1329	51	121	one	one	NUM
ecletica-1329	51	122	1.37	1.37	NUM
ecletica-1329	51	123	c7	c7	PROPN
ecletica-1329	51	124	(	(	PUNCT
ecletica-1329	51	125	z)-5	z)-5	NOUN
ecletica-1329	51	126	-	-	PUNCT
ecletica-1329	51	127	chloro-3-((4-(3,4	chloro-3-((4-(3,4	ADJ
ecletica-1329	51	128	-	-	PUNCT
ecletica-1329	51	129	dimethoxyphen	dimethoxyphen	NOUN
ecletica-1329	51	130	yl)5,6,7,8	yl)5,6,7,8	NOUN
ecletica-1329	51	131	-	-	PUNCT
ecletica-1329	51	132	tetrahydro-1h	tetrahydro-1h	NOUN
ecletica-1329	51	133	-	-	PUNCT
ecletica-1329	51	134	pyrazolo[3,4	pyrazolo[3,4	ADJ
ecletica-1329	51	135	-	-	PUNCT
ecletica-1329	51	136	b	b	NOUN
ecletica-1329	51	137	]	]	X
ecletica-1329	51	138	quinolin-3yl)imino)indo	quinolin-3yl)imino)indo	X
ecletica-1329	51	139	lin-2	lin-2	NOUN
ecletica-1329	51	140	-	-	NUM
ecletica-1329	51	141	one	one	NUM
ecletica-1329	51	142	1.20	1.20	NUM
ecletica-1329	51	143	c8	c8	NOUN
ecletica-1329	51	144	(	(	PUNCT
ecletica-1329	51	145	z)-5	z)-5	NOUN
ecletica-1329	51	146	-	-	PUNCT
ecletica-1329	51	147	bromo-3-((4-(3,4	bromo-3-((4-(3,4	ADJ
ecletica-1329	51	148	-	-	PUNCT
ecletica-1329	51	149	dimethoxyphenyl)5,6,7,8	dimethoxyphenyl)5,6,7,8	PRON
ecletica-1329	51	150	-	-	PUNCT
ecletica-1329	51	151	tetrahydro-1h	tetrahydro-1h	NOUN
ecletica-1329	51	152	-	-	PUNCT
ecletica-1329	51	153	pyrazolo	pyrazolo	NOUN
ecletica-1329	51	154	[	[	X
ecletica-1329	51	155	3,4	3,4	NUM
ecletica-1329	51	156	-	-	PUNCT
ecletica-1329	51	157	b]quinolin-3yl)imino)indolin-2	b]quinolin-3yl)imino)indolin-2	NOUN
ecletica-1329	51	158	-	-	PUNCT
ecletica-1329	51	159	one	one	NUM
ecletica-1329	51	160	1.10	1.10	NUM
ecletica-1329	51	161	c9	c9	NOUN
ecletica-1329	51	162	ethyl-2-((3	ethyl-2-((3	NOUN
ecletica-1329	51	163	-	-	PUNCT
ecletica-1329	51	164	cyano-4-(3,4	cyano-4-(3,4	ADV
ecletica-1329	51	165	-	-	PUNCT
ecletica-1329	51	166	dimethoxy	dimethoxy	ADJ
ecletica-1329	51	167	phenyl)5,6,7,8	phenyl)5,6,7,8	NOUN
ecletica-1329	51	168	-	-	PUNCT
ecletica-1329	51	169	tetrahydroquinolin-2	tetrahydroquinolin-2	NOUN
ecletica-1329	51	170	-	-	PUNCT
ecletica-1329	51	171	yl)oxy)acetate	yl)oxy)acetate	PROPN
ecletica-1329	51	172	39.60	39.60	NUM
ecletica-1329	51	173	continue	continue	NOUN
ecletica-1329	51	174	…	…	PUNCT
ecletica-1329	51	175	https://revista.iq.unesp.br/index.php/ecletica	https://revista.iq.unesp.br/index.php/ecletica	PROPN
ecletica-1329	51	176	https://doi.org/10.26850/1678-4618eqj.v48.1.2023.p55-71	https://doi.org/10.26850/1678-4618eqj.v48.1.2023.p55-71	PROPN
ecletica-1329	51	177	original	original	ADJ
ecletica-1329	51	178	article	article	NOUN
ecletica-1329	51	179	revista.iq.unesp.br	revista.iq.unesp.br	PROPN
ecletica-1329	51	180	59	59	NUM
ecletica-1329	51	181	eclética	eclética	PROPN
ecletica-1329	51	182	química	química	PROPN
ecletica-1329	51	183	,	,	PUNCT
ecletica-1329	51	184	vol	vol	NOUN
ecletica-1329	51	185	.	.	PROPN
ecletica-1329	51	186	48	48	NUM
ecletica-1329	51	187	,	,	PUNCT
ecletica-1329	51	188	n.	n.	NOUN
ecletica-1329	51	189	1	1	NUM
ecletica-1329	51	190	,	,	PUNCT
ecletica-1329	51	191	2023	2023	NUM
ecletica-1329	51	192	,	,	PUNCT
ecletica-1329	51	193	55	55	NUM
ecletica-1329	51	194	-	-	SYM
ecletica-1329	51	195	71	71	NUM
ecletica-1329	51	196	issn	issn	NOUN
ecletica-1329	51	197	:	:	PUNCT
ecletica-1329	51	198	1678	1678	NUM
ecletica-1329	51	199	-	-	SYM
ecletica-1329	51	200	4618	4618	NUM
ecletica-1329	51	201	doi	doi	NOUN
ecletica-1329	51	202	:	:	PUNCT
ecletica-1329	51	203	10.26850/1678	10.26850/1678	NUM
ecletica-1329	51	204	-	-	PUNCT
ecletica-1329	51	205	4618eqj.v48.1.2023.p55	4618eqj.v48.1.2023.p55	NUM
ecletica-1329	51	206	-	-	PUNCT
ecletica-1329	51	207	71	71	NUM
ecletica-1329	51	208	c10	c10	VERB
ecletica-1329	51	209	2-((3	2-((3	NUM
ecletica-1329	51	210	-	-	PUNCT
ecletica-1329	51	211	cyano-4-(3,4	cyano-4-(3,4	NUM
ecletica-1329	51	212	-	-	PUNCT
ecletica-1329	51	213	dimethoxyphenyl)-5,6,7,8tetrahydroquinolin-2	dimethoxyphenyl)-5,6,7,8tetrahydroquinolin-2	NOUN
ecletica-1329	51	214	-	-	PUNCT
ecletica-1329	51	215	yl)oxy)acetohydrazide	yl)oxy)acetohydrazide	NOUN
ecletica-1329	51	216	4.24	4.24	NUM
ecletica-1329	51	217	c11	c11	NOUN
ecletica-1329	51	218	(	(	PUNCT
ecletica-1329	51	219	e)-2-((3	e)-2-((3	ADJ
ecletica-1329	51	220	-	-	PUNCT
ecletica-1329	51	221	cyano-4-(3,4	cyano-4-(3,4	ADV
ecletica-1329	51	222	-	-	PUNCT
ecletica-1329	51	223	dimethoxyphenyl)5,6,7,8	dimethoxyphenyl)5,6,7,8	NOUN
ecletica-1329	51	224	-	-	PUNCT
ecletica-1329	51	225	tetrahydroquinolin-2	tetrahydroquinolin-2	NOUN
ecletica-1329	51	226	-	-	PUNCT
ecletica-1329	51	227	yl)oxy)-n'-(3methylbenzylidene)acetohydrazide	yl)oxy)-n'-(3methylbenzylidene)acetohydrazide	PROPN
ecletica-1329	51	228	3.10	3.10	NUM
ecletica-1329	51	229	c12	c12	NOUN
ecletica-1329	51	230	(	(	PUNCT
ecletica-1329	51	231	e)-2-((3	e)-2-((3	ADJ
ecletica-1329	51	232	-	-	PUNCT
ecletica-1329	51	233	cyano-4-(3,4	cyano-4-(3,4	ADV
ecletica-1329	51	234	-	-	PUNCT
ecletica-1329	51	235	dimethoxyphenyl)5,6,7,8	dimethoxyphenyl)5,6,7,8	NOUN
ecletica-1329	51	236	-	-	PUNCT
ecletica-1329	51	237	tetrahydroquinolin-2	tetrahydroquinolin-2	NUM
ecletica-1329	51	238	-	-	PUNCT
ecletica-1329	51	239	yl)oxy)-n'-(2oxoindolin-3	yl)oxy)-n'-(2oxoindolin-3	NOUN
ecletica-1329	51	240	-	-	PUNCT
ecletica-1329	51	241	yliden	yliden	ADJ
ecletica-1329	51	242	e)acetohydrazide	e)acetohydrazide	ADV
ecletica-1329	51	243	2.00	2.00	NUM
ecletica-1329	51	244	c13	c13	NOUN
ecletica-1329	51	245	(	(	PUNCT
ecletica-1329	51	246	e)-n'-(5	e)-n'-(5	ADJ
ecletica-1329	51	247	-	-	PUNCT
ecletica-1329	51	248	chloro-2	chloro-2	VERB
ecletica-1329	51	249	-	-	PUNCT
ecletica-1329	51	250	oxoindolin-3	oxoindolin-3	NUM
ecletica-1329	51	251	-	-	PUNCT
ecletica-1329	51	252	ylidene)-2-((3cyano-4-(3,4	ylidene)-2-((3cyano-4-(3,4	NOUN
ecletica-1329	51	253	-	-	PUNCT
ecletica-1329	51	254	dimethoxyphenyl)-5,6,7,8tetrahydroquinolin-2	dimethoxyphenyl)-5,6,7,8tetrahydroquinolin-2	NOUN
ecletica-1329	51	255	-	-	PUNCT
ecletica-1329	51	256	yl)oxy)acetohydrazide	yl)oxy)acetohydrazide	PROPN
ecletica-1329	51	257	1.06	1.06	NUM
ecletica-1329	51	258	c14	c14	NOUN
ecletica-1329	51	259	(	(	PUNCT
ecletica-1329	51	260	e)-n'-(5	e)-n'-(5	NOUN
ecletica-1329	51	261	-	-	PUNCT
ecletica-1329	51	262	bromo-2	bromo-2	VERB
ecletica-1329	51	263	-	-	PUNCT
ecletica-1329	51	264	oxoindolin-3	oxoindolin-3	NUM
ecletica-1329	51	265	-	-	PUNCT
ecletica-1329	51	266	ylidene)-2-((3cyano-4-(3,4	ylidene)-2-((3cyano-4-(3,4	NOUN
ecletica-1329	51	267	-	-	PUNCT
ecletica-1329	51	268	dimethoxylphenyl)-5,6,7,8tetrahydroquinolin-2	dimethoxylphenyl)-5,6,7,8tetrahydroquinolin-2	NOUN
ecletica-1329	51	269	-	-	PUNCT
ecletica-1329	51	270	yl)ox	yl)ox	NOUN
ecletica-1329	51	271	y)acetohydrazide	y)acetohydrazide	ADJ
ecletica-1329	51	272	0.69	0.69	NUM
ecletica-1329	51	273	5	5	NUM
ecletica-1329	51	274	-	-	PUNCT
ecletica-1329	51	275	fu	fu	NOUN
ecletica-1329	51	276	5	5	NUM
ecletica-1329	51	277	-	-	PUNCT
ecletica-1329	51	278	flurouracil	flurouracil	NOUN
ecletica-1329	51	279	0.60	0.60	NUM
ecletica-1329	51	280	5	5	NUM
ecletica-1329	51	281	-	-	PUNCT
ecletica-1329	51	282	fu	fu	NOUN
ecletica-1329	51	283	:	:	PUNCT
ecletica-1329	51	284	5	5	NUM
ecletica-1329	51	285	-	-	PUNCT
ecletica-1329	51	286	flurouracil	flurouracil	NOUN
ecletica-1329	51	287	.	.	PUNCT
ecletica-1329	52	1	source	source	NOUN
ecletica-1329	52	2	:	:	PUNCT
ecletica-1329	52	3	fathy	fathy	PROPN
ecletica-1329	52	4	et	et	PROPN
ecletica-1329	52	5	al	al	PROPN
ecletica-1329	52	6	.	.	PROPN
ecletica-1329	53	1	(	(	PUNCT
ecletica-1329	53	2	2020	2020	NUM
ecletica-1329	53	3	)	)	PUNCT
ecletica-1329	53	4	https://revista.iq.unesp.br/index.php/ecletica	https://revista.iq.unesp.br/index.php/ecletica	PROPN
ecletica-1329	53	5	https://doi.org/10.26850/1678-4618eqj.v48.1.2023.p55-71	https://doi.org/10.26850/1678-4618eqj.v48.1.2023.p55-71	PROPN
ecletica-1329	53	6	original	original	ADJ
ecletica-1329	53	7	article	article	NOUN
ecletica-1329	53	8	revista.iq.unesp.br	revista.iq.unesp.br	PROPN
ecletica-1329	53	9	60	60	NUM
ecletica-1329	53	10	eclética	eclética	PROPN
ecletica-1329	53	11	química	química	PROPN
ecletica-1329	53	12	,	,	PUNCT
ecletica-1329	53	13	vol	vol	NOUN
ecletica-1329	53	14	.	.	PROPN
ecletica-1329	53	15	48	48	NUM
ecletica-1329	53	16	,	,	PUNCT
ecletica-1329	53	17	n.	n.	NOUN
ecletica-1329	53	18	1	1	NUM
ecletica-1329	53	19	,	,	PUNCT
ecletica-1329	53	20	2023	2023	NUM
ecletica-1329	53	21	,	,	PUNCT
ecletica-1329	53	22	55	55	NUM
ecletica-1329	53	23	-	-	SYM
ecletica-1329	53	24	71	71	NUM
ecletica-1329	53	25	issn	issn	NOUN
ecletica-1329	53	26	:	:	PUNCT
ecletica-1329	53	27	1678	1678	NUM
ecletica-1329	53	28	-	-	SYM
ecletica-1329	53	29	4618	4618	NUM
ecletica-1329	53	30	doi	doi	NOUN
ecletica-1329	53	31	:	:	PUNCT
ecletica-1329	53	32	10.26850/1678	10.26850/1678	NUM
ecletica-1329	53	33	-	-	PUNCT
ecletica-1329	53	34	4618eqj.v48.1.2023.p55	4618eqj.v48.1.2023.p55	NUM
ecletica-1329	53	35	-	-	PUNCT
ecletica-1329	53	36	71	71	NUM
ecletica-1329	53	37	2.3	2.3	NUM
ecletica-1329	53	38	qsar	qsar	NOUN
ecletica-1329	53	39	modelling	model	VERB
ecletica-1329	53	40	the	the	DET
ecletica-1329	53	41	obtained	obtain	VERB
ecletica-1329	53	42	descriptors	descriptor	NOUN
ecletica-1329	53	43	were	be	AUX
ecletica-1329	53	44	extracted	extract	VERB
ecletica-1329	53	45	from	from	ADP
ecletica-1329	53	46	the	the	DET
ecletica-1329	53	47	optimized	optimize	VERB
ecletica-1329	53	48	compounds	compound	NOUN
ecletica-1329	53	49	together	together	ADV
ecletica-1329	53	50	and	and	CCONJ
ecletica-1329	53	51	were	be	AUX
ecletica-1329	53	52	used	use	VERB
ecletica-1329	53	53	in	in	ADP
ecletica-1329	53	54	developing	develop	VERB
ecletica-1329	53	55	valid	valid	ADJ
ecletica-1329	53	56	and	and	CCONJ
ecletica-1329	53	57	reliable	reliable	ADJ
ecletica-1329	53	58	qsar	qsar	NOUN
ecletica-1329	53	59	model	model	NOUN
ecletica-1329	53	60	.	.	PUNCT
ecletica-1329	54	1	the	the	DET
ecletica-1329	54	2	extracted	extract	VERB
ecletica-1329	54	3	descriptors	descriptor	NOUN
ecletica-1329	54	4	were	be	AUX
ecletica-1329	54	5	used	use	VERB
ecletica-1329	54	6	as	as	ADP
ecletica-1329	54	7	independent	independent	ADJ
ecletica-1329	54	8	variable	variable	NOUN
ecletica-1329	54	9	and	and	CCONJ
ecletica-1329	54	10	the	the	DET
ecletica-1329	54	11	experimental	experimental	ADJ
ecletica-1329	54	12	inhibition	inhibition	NOUN
ecletica-1329	54	13	concentration	concentration	NOUN
ecletica-1329	54	14	(	(	PUNCT
ecletica-1329	54	15	ic50	ic50	PROPN
ecletica-1329	54	16	)	)	PUNCT
ecletica-1329	54	17	was	be	AUX
ecletica-1329	54	18	used	use	VERB
ecletica-1329	54	19	as	as	ADP
ecletica-1329	54	20	dependent	dependent	ADJ
ecletica-1329	54	21	variable	variable	NOUN
ecletica-1329	54	22	.	.	PUNCT
ecletica-1329	55	1	the	the	DET
ecletica-1329	55	2	qsar	qsar	PROPN
ecletica-1329	55	3	model	model	PROPN
ecletica-1329	55	4	development	development	NOUN
ecletica-1329	55	5	was	be	AUX
ecletica-1329	55	6	achieved	achieve	VERB
ecletica-1329	55	7	using	use	VERB
ecletica-1329	55	8	genetic	genetic	ADJ
ecletica-1329	55	9	function	function	NOUN
ecletica-1329	55	10	approximation	approximation	NOUN
ecletica-1329	55	11	(	(	PUNCT
ecletica-1329	55	12	gfa	gfa	PROPN
ecletica-1329	55	13	)	)	PUNCT
ecletica-1329	55	14	via	via	ADP
ecletica-1329	55	15	material	material	NOUN
ecletica-1329	55	16	studio	studio	NOUN
ecletica-1329	55	17	software	software	NOUN
ecletica-1329	55	18	(	(	PUNCT
ecletica-1329	55	19	puzyn	puzyn	PROPN
ecletica-1329	55	20	et	et	PROPN
ecletica-1329	55	21	al	al	PROPN
ecletica-1329	55	22	.	.	PROPN
ecletica-1329	55	23	,	,	PUNCT
ecletica-1329	55	24	2010	2010	NUM
ecletica-1329	55	25	)	)	PUNCT
ecletica-1329	55	26	and	and	CCONJ
ecletica-1329	55	27	the	the	DET
ecletica-1329	55	28	mlr	mlr	PROPN
ecletica-1329	55	29	-	-	PROPN
ecletica-1329	55	30	gfa	gfa	PROPN
ecletica-1329	55	31	equation	equation	NOUN
ecletica-1329	55	32	for	for	ADP
ecletica-1329	55	33	the	the	DET
ecletica-1329	55	34	model	model	NOUN
ecletica-1329	55	35	is	be	AUX
ecletica-1329	55	36	shown	show	VERB
ecletica-1329	55	37	in	in	ADP
ecletica-1329	55	38	eq	eq	NOUN
ecletica-1329	55	39	.	.	PROPN
ecletica-1329	55	40	1	1	NUM
ecletica-1329	55	41	below	below	ADV
ecletica-1329	55	42	:	:	PUNCT
ecletica-1329	55	43	predicted	predict	VERB
ecletica-1329	55	44	ic50	ic50	PROPN
ecletica-1329	55	45	=	=	PUNCT
ecletica-1329	55	46	α	α	PROPN
ecletica-1329	56	1	+	+	X
ecletica-1329	57	1	β1x1	β1x1	PUNCT
ecletica-1329	58	1	+	+	NUM
ecletica-1329	58	2	β2x2	β2x2	PUNCT
ecletica-1329	58	3	+	+	CCONJ
ecletica-1329	58	4	..........	..........	PUNCT
ecletica-1329	59	1	+	+	NUM
ecletica-1329	59	2	βnxn	βnxn	NOUN
ecletica-1329	59	3	(	(	PUNCT
ecletica-1329	59	4	1	1	NUM
ecletica-1329	59	5	)	)	PUNCT
ecletica-1329	59	6	where	where	SCONJ
ecletica-1329	59	7	α	α	NOUN
ecletica-1329	59	8	is	be	AUX
ecletica-1329	59	9	the	the	DET
ecletica-1329	59	10	regression	regression	NOUN
ecletica-1329	59	11	constant	constant	ADJ
ecletica-1329	59	12	,	,	PUNCT
ecletica-1329	59	13	x1	x1	PROPN
ecletica-1329	59	14	,	,	PUNCT
ecletica-1329	59	15	x2	x2	PROPN
ecletica-1329	59	16	....	....	PUNCT
ecletica-1329	59	17	xn	xn	PROPN
ecletica-1329	59	18	are	be	AUX
ecletica-1329	59	19	the	the	DET
ecletica-1329	59	20	descriptors	descriptor	NOUN
ecletica-1329	59	21	and	and	CCONJ
ecletica-1329	59	22	β1	β1	PROPN
ecletica-1329	59	23	,	,	PUNCT
ecletica-1329	59	24	β2	β2	NOUN
ecletica-1329	59	25	…	…	SYM
ecletica-1329	59	26	βn	βn	NOUN
ecletica-1329	59	27	are	be	AUX
ecletica-1329	59	28	the	the	DET
ecletica-1329	59	29	coefficient	coefficient	NOUN
ecletica-1329	59	30	of	of	ADP
ecletica-1329	59	31	the	the	DET
ecletica-1329	59	32	corresponding	corresponding	ADJ
ecletica-1329	59	33	descriptors	descriptor	NOUN
ecletica-1329	59	34	.	.	PUNCT
ecletica-1329	60	1	the	the	DET
ecletica-1329	60	2	developed	develop	VERB
ecletica-1329	60	3	qsar	qsar	NOUN
ecletica-1329	60	4	model	model	NOUN
ecletica-1329	60	5	was	be	AUX
ecletica-1329	60	6	validated	validate	VERB
ecletica-1329	60	7	by	by	ADP
ecletica-1329	60	8	considering	consider	VERB
ecletica-1329	60	9	series	series	NOUN
ecletica-1329	60	10	of	of	ADP
ecletica-1329	60	11	statistic	statistic	ADJ
ecletica-1329	60	12	factors	factor	NOUN
ecletica-1329	60	13	such	such	ADJ
ecletica-1329	60	14	cross	cross	VERB
ecletica-1329	60	15	validation	validation	NOUN
ecletica-1329	60	16	r2	r2	NOUN
ecletica-1329	60	17	(	(	PUNCT
ecletica-1329	60	18	𝐶𝑉.	𝐶𝑉.	NOUN
ecletica-1329	60	19	𝑅2	𝑅2	NOUN
ecletica-1329	60	20	)	)	PUNCT
ecletica-1329	60	21	and	and	CCONJ
ecletica-1329	60	22	adjusted	adjust	VERB
ecletica-1329	60	23	r2	r2	PROPN
ecletica-1329	60	24	(	(	PUNCT
ecletica-1329	60	25	𝑅𝑎	𝑅𝑎	PROPN
ecletica-1329	60	26	2	2	NUM
ecletica-1329	60	27	)	)	PUNCT
ecletica-1329	60	28	(	(	PUNCT
ecletica-1329	60	29	eqs	eqs	X
ecletica-1329	60	30	.	.	PROPN
ecletica-1329	60	31	2	2	NUM
ecletica-1329	60	32	and	and	CCONJ
ecletica-1329	60	33	3	3	NUM
ecletica-1329	60	34	)	)	PUNCT
ecletica-1329	60	35	and	and	CCONJ
ecletica-1329	60	36	the	the	DET
ecletica-1329	60	37	developed	develop	VERB
ecletica-1329	60	38	model	model	NOUN
ecletica-1329	60	39	will	will	AUX
ecletica-1329	60	40	be	be	AUX
ecletica-1329	60	41	considered	consider	VERB
ecletica-1329	60	42	valid	valid	ADJ
ecletica-1329	60	43	when	when	SCONJ
ecletica-1329	60	44	the	the	DET
ecletica-1329	60	45	calculated	calculate	VERB
ecletica-1329	60	46	value	value	NOUN
ecletica-1329	60	47	for	for	ADP
ecletica-1329	60	48	𝑅𝑎	𝑅𝑎	PROPN
ecletica-1329	60	49	2	2	NUM
ecletica-1329	60	50	and	and	CCONJ
ecletica-1329	60	51	𝐶𝑉.	𝐶𝑉.	ADJ
ecletica-1329	60	52	𝑅2	𝑅2	NOUN
ecletica-1329	60	53	were	be	AUX
ecletica-1329	60	54	≥	≥	NOUN
ecletica-1329	60	55	0.6	0.6	NUM
ecletica-1329	60	56	and	and	CCONJ
ecletica-1329	60	57	≥	≥	NUM
ecletica-1329	60	58	0.5	0.5	NUM
ecletica-1329	60	59	respectively	respectively	ADV
ecletica-1329	60	60	.	.	PUNCT
ecletica-1329	61	1	𝐶𝑉.	𝐶𝑉.	NOUN
ecletica-1329	61	2	𝑅2	𝑅2	NOUN
ecletica-1329	61	3	=	=	SYM
ecletica-1329	61	4	1	1	NUM
ecletica-1329	61	5	−	−	NOUN
ecletica-1329	61	6	∑(𝑌𝑜𝑏𝑠−𝑌𝑐𝑎𝑙)2	∑(𝑌𝑜𝑏𝑠−𝑌𝑐𝑎𝑙)2	NOUN
ecletica-1329	61	7	∑(𝑌𝑜𝑏𝑠−	∑(𝑌𝑜𝑏𝑠−	PROPN
ecletica-1329	61	8	�	�	PROPN
ecletica-1329	61	9	̅	̅	NOUN
ecletica-1329	61	10	�	�	NOUN
ecletica-1329	61	11	𝑜𝑏𝑠2	𝑜𝑏𝑠2	PROPN
ecletica-1329	61	12	)	)	PUNCT
ecletica-1329	61	13	(	(	PUNCT
ecletica-1329	61	14	2	2	X
ecletica-1329	61	15	)	)	PUNCT
ecletica-1329	61	16	where	where	SCONJ
ecletica-1329	61	17	𝑌𝑜𝑏𝑠	𝑌𝑜𝑏𝑠	PROPN
ecletica-1329	61	18	=	=	PUNCT
ecletica-1329	61	19	experimentally	experimentally	ADV
ecletica-1329	61	20	observed	observe	VERB
ecletica-1329	61	21	ic50	ic50	PROPN
ecletica-1329	61	22	,	,	PUNCT
ecletica-1329	61	23	𝑌𝑐𝑎𝑙	𝑌𝑐𝑎𝑙	PROPN
ecletica-1329	61	24	=	=	PRON
ecletica-1329	61	25	calculated	calculate	VERB
ecletica-1329	61	26	ic50	ic50	PROPN
ecletica-1329	61	27	and	and	CCONJ
ecletica-1329	61	28	�	�	NOUN
ecletica-1329	61	29	̅	̅	NOUN
ecletica-1329	61	30	�	�	NOUN
ecletica-1329	61	31	𝑜𝑏𝑠	𝑜𝑏𝑠	NOUN
ecletica-1329	61	32	=	=	SYM
ecletica-1329	61	33	average	average	NOUN
ecletica-1329	61	34	of	of	ADP
ecletica-1329	61	35	the	the	DET
ecletica-1329	61	36	experimentally	experimentally	ADV
ecletica-1329	61	37	observed	observe	VERB
ecletica-1329	61	38	ic50	ic50	PROPN
ecletica-1329	61	39	𝑅𝑎	𝑅𝑎	PROPN
ecletica-1329	61	40	2	2	NUM
ecletica-1329	61	41	=	=	SYM
ecletica-1329	61	42	(	(	PUNCT
ecletica-1329	61	43	𝑁−1)×𝑅2−𝑃	𝑁−1)×𝑅2−𝑃	NOUN
ecletica-1329	61	44	𝑁−1−𝑃	𝑁−1−𝑃	PROPN
ecletica-1329	61	45	(	(	PUNCT
ecletica-1329	61	46	3	3	NUM
ecletica-1329	61	47	)	)	PUNCT
ecletica-1329	61	48	where	where	SCONJ
ecletica-1329	61	49	n	n	NOUN
ecletica-1329	61	50	=	=	SYM
ecletica-1329	61	51	no	no	PROPN
ecletica-1329	61	52	of	of	ADP
ecletica-1329	61	53	compounds	compound	NOUN
ecletica-1329	61	54	observed	observe	VERB
ecletica-1329	61	55	,	,	PUNCT
ecletica-1329	61	56	p	p	X
ecletica-1329	61	57	=	=	PUNCT
ecletica-1329	61	58	no	no	PROPN
ecletica-1329	61	59	of	of	ADP
ecletica-1329	61	60	molecular	molecular	ADJ
ecletica-1329	61	61	descriptors	descriptor	NOUN
ecletica-1329	61	62	used	use	VERB
ecletica-1329	61	63	in	in	ADP
ecletica-1329	61	64	the	the	DET
ecletica-1329	61	65	qsar	qsar	NOUN
ecletica-1329	61	66	model	model	NOUN
ecletica-1329	61	67	and	and	CCONJ
ecletica-1329	61	68	r2	r2	PROPN
ecletica-1329	61	69	=	=	SYM
ecletica-1329	61	70	rsquared	rsquare	VERB
ecletica-1329	61	71	value	value	NOUN
ecletica-1329	61	72	obtained	obtain	VERB
ecletica-1329	61	73	from	from	ADP
ecletica-1329	61	74	the	the	DET
ecletica-1329	61	75	qsar	qsar	NOUN
ecletica-1329	61	76	model	model	NOUN
ecletica-1329	61	77	.	.	PUNCT
ecletica-1329	62	1	2.4	2.4	NUM
ecletica-1329	62	2	molecular	molecular	ADJ
ecletica-1329	62	3	docking	docking	NOUN
ecletica-1329	62	4	crystal	crystal	NOUN
ecletica-1329	62	5	structure	structure	NOUN
ecletica-1329	62	6	of	of	ADP
ecletica-1329	62	7	the	the	DET
ecletica-1329	62	8	egfr	egfr	NOUN
ecletica-1329	62	9	(	(	PUNCT
ecletica-1329	62	10	pdb	pdb	PROPN
ecletica-1329	62	11	i	i	NOUN
ecletica-1329	62	12	d	d	PROPN
ecletica-1329	62	13	:	:	PUNCT
ecletica-1329	62	14	4lrm	4lrm	NUM
ecletica-1329	62	15	)	)	PUNCT
ecletica-1329	62	16	(	(	PUNCT
ecletica-1329	62	17	yasuda	yasuda	NOUN
ecletica-1329	62	18	et	et	PROPN
ecletica-1329	62	19	al	al	PROPN
ecletica-1329	62	20	.	.	PROPN
ecletica-1329	62	21	,	,	PUNCT
ecletica-1329	62	22	2013	2013	NUM
ecletica-1329	62	23	)	)	PUNCT
ecletica-1329	62	24	was	be	AUX
ecletica-1329	62	25	retrieved	retrieve	VERB
ecletica-1329	62	26	from	from	ADP
ecletica-1329	62	27	the	the	DET
ecletica-1329	62	28	protein	protein	NOUN
ecletica-1329	62	29	data	datum	NOUN
ecletica-1329	62	30	bank	bank	NOUN
ecletica-1329	62	31	(	(	PUNCT
ecletica-1329	62	32	https://www.rcsb.org/	https://www.rcsb.org/	ADV
ecletica-1329	62	33	)	)	PUNCT
ecletica-1329	62	34	(	(	PUNCT
ecletica-1329	62	35	yasuda	yasuda	NOUN
ecletica-1329	62	36	et	et	PROPN
ecletica-1329	62	37	al	al	PROPN
ecletica-1329	62	38	.	.	PROPN
ecletica-1329	62	39	,	,	PUNCT
ecletica-1329	62	40	2013	2013	NUM
ecletica-1329	62	41	)	)	PUNCT
ecletica-1329	62	42	and	and	CCONJ
ecletica-1329	62	43	employed	employ	VERB
ecletica-1329	62	44	as	as	ADP
ecletica-1329	62	45	target	target	NOUN
ecletica-1329	62	46	receptors	receptor	NOUN
ecletica-1329	62	47	in	in	ADP
ecletica-1329	62	48	this	this	DET
ecletica-1329	62	49	study	study	NOUN
ecletica-1329	62	50	.	.	PUNCT
ecletica-1329	63	1	also	also	ADV
ecletica-1329	63	2	,	,	PUNCT
ecletica-1329	63	3	the	the	DET
ecletica-1329	63	4	tetrahydroquinoline	tetrahydroquinoline	ADJ
ecletica-1329	63	5	derivatives	derivative	NOUN
ecletica-1329	63	6	(	(	PUNCT
ecletica-1329	63	7	table	table	NOUN
ecletica-1329	63	8	1	1	NUM
ecletica-1329	63	9	)	)	PUNCT
ecletica-1329	63	10	synthesized	synthesize	VERB
ecletica-1329	63	11	by	by	ADP
ecletica-1329	63	12	fathy	fathy	PROPN
ecletica-1329	63	13	et	et	PROPN
ecletica-1329	63	14	al	al	PROPN
ecletica-1329	63	15	.	.	PROPN
ecletica-1329	63	16	(	(	PUNCT
ecletica-1329	63	17	2020	2020	NUM
ecletica-1329	63	18	)	)	PUNCT
ecletica-1329	63	19	were	be	AUX
ecletica-1329	63	20	used	use	VERB
ecletica-1329	63	21	as	as	ADP
ecletica-1329	63	22	ligands	ligand	NOUN
ecletica-1329	63	23	.	.	PUNCT
ecletica-1329	64	1	the	the	DET
ecletica-1329	64	2	2d	2d	NUM
ecletica-1329	64	3	structures	structure	NOUN
ecletica-1329	64	4	of	of	ADP
ecletica-1329	64	5	the	the	DET
ecletica-1329	64	6	ligands	ligand	NOUN
ecletica-1329	64	7	were	be	AUX
ecletica-1329	64	8	drawn	draw	VERB
ecletica-1329	64	9	with	with	ADP
ecletica-1329	64	10	the	the	DET
ecletica-1329	64	11	help	help	NOUN
ecletica-1329	64	12	of	of	ADP
ecletica-1329	64	13	chem	chem	NOUN
ecletica-1329	64	14	professional	professional	NOUN
ecletica-1329	64	15	15.0	15.0	NUM
ecletica-1329	64	16	and	and	CCONJ
ecletica-1329	64	17	saved	save	VERB
ecletica-1329	64	18	as	as	ADP
ecletica-1329	64	19	structure	structure	NOUN
ecletica-1329	64	20	-	-	PUNCT
ecletica-1329	64	21	data	datum	NOUN
ecletica-1329	64	22	files	file	NOUN
ecletica-1329	64	23	(	(	PUNCT
ecletica-1329	64	24	sdfs	sdfs	NOUN
ecletica-1329	64	25	)	)	PUNCT
ecletica-1329	64	26	.	.	PUNCT
ecletica-1329	65	1	chimera	chimera	PROPN
ecletica-1329	65	2	1.14	1.14	NUM
ecletica-1329	65	3	was	be	AUX
ecletica-1329	65	4	employed	employ	VERB
ecletica-1329	65	5	to	to	PART
ecletica-1329	65	6	prepare	prepare	VERB
ecletica-1329	65	7	the	the	DET
ecletica-1329	65	8	protein	protein	NOUN
ecletica-1329	65	9	by	by	ADP
ecletica-1329	65	10	eliminating	eliminate	VERB
ecletica-1329	65	11	water	water	NOUN
ecletica-1329	65	12	molecules	molecule	NOUN
ecletica-1329	65	13	,	,	PUNCT
ecletica-1329	65	14	numerous	numerous	ADJ
ecletica-1329	65	15	ligands	ligand	NOUN
ecletica-1329	65	16	,	,	PUNCT
ecletica-1329	65	17	nonprotein	nonprotein	NOUN
ecletica-1329	65	18	component	component	NOUN
ecletica-1329	65	19	,	,	PUNCT
ecletica-1329	65	20	and	and	CCONJ
ecletica-1329	65	21	other	other	ADJ
ecletica-1329	65	22	extraneous	extraneous	ADJ
ecletica-1329	65	23	substances	substance	NOUN
ecletica-1329	65	24	downloaded	download	VERB
ecletica-1329	65	25	together	together	ADV
ecletica-1329	65	26	with	with	ADP
ecletica-1329	65	27	the	the	DET
ecletica-1329	65	28	proteins	protein	NOUN
ecletica-1329	65	29	(	(	PUNCT
ecletica-1329	65	30	pettersen	pettersen	NOUN
ecletica-1329	65	31	et	et	PROPN
ecletica-1329	65	32	al	al	PROPN
ecletica-1329	65	33	.	.	PROPN
ecletica-1329	65	34	,	,	PUNCT
ecletica-1329	65	35	2004	2004	NUM
ecletica-1329	65	36	)	)	PUNCT
ecletica-1329	65	37	.	.	PUNCT
ecletica-1329	66	1	the	the	DET
ecletica-1329	66	2	ligands	ligand	NOUN
ecletica-1329	66	3	were	be	AUX
ecletica-1329	66	4	saved	save	VERB
ecletica-1329	66	5	as	as	SCONJ
ecletica-1329	66	6	sdf	sdf	NOUN
ecletica-1329	66	7	files	file	NOUN
ecletica-1329	66	8	and	and	CCONJ
ecletica-1329	66	9	treated	treat	VERB
ecletica-1329	66	10	protein	protein	NOUN
ecletica-1329	66	11	was	be	AUX
ecletica-1329	66	12	converted	convert	VERB
ecletica-1329	66	13	to	to	ADP
ecletica-1329	66	14	pdbqt	pdbqt	ADJ
ecletica-1329	66	15	format	format	NOUN
ecletica-1329	66	16	using	use	VERB
ecletica-1329	66	17	autodock	autodock	NOUN
ecletica-1329	66	18	tool	tool	NOUN
ecletica-1329	66	19	4.2	4.2	NUM
ecletica-1329	66	20	.	.	PUNCT
ecletica-1329	67	1	grid	grid	NOUN
ecletica-1329	67	2	box	box	PROPN
ecletica-1329	67	3	size	size	NOUN
ecletica-1329	67	4	x	x	X
ecletica-1329	67	5	=	=	PUNCT
ecletica-1329	67	6	18.49	18.49	NUM
ecletica-1329	67	7	å	å	PROPN
ecletica-1329	67	8	,	,	PUNCT
ecletica-1329	67	9	y	y	PROPN
ecletica-1329	67	10	=	=	PROPN
ecletica-1329	67	11	22.59	22.59	NUM
ecletica-1329	67	12	å	å	NOUN
ecletica-1329	67	13	,	,	PUNCT
ecletica-1329	67	14	size	size	NOUN
ecletica-1329	67	15	z	z	NOUN
ecletica-1329	67	16	=	=	SYM
ecletica-1329	67	17	17.09	17.09	NUM
ecletica-1329	67	18	å	å	PROPN
ecletica-1329	67	19	and	and	CCONJ
ecletica-1329	67	20	grid	grid	NOUN
ecletica-1329	67	21	center	center	NOUN
ecletica-1329	67	22	dimensions	dimension	NOUN
ecletica-1329	67	23	x	x	PUNCT
ecletica-1329	68	1	=	=	SYM
ecletica-1329	68	2	41.77	41.77	NUM
ecletica-1329	68	3	,	,	PUNCT
ecletica-1329	68	4	y	y	PROPN
ecletica-1329	68	5	=	=	SYM
ecletica-1329	68	6	361.60	361.60	NUM
ecletica-1329	68	7	and	and	CCONJ
ecletica-1329	68	8	z	z	NOUN
ecletica-1329	68	9	=	=	SYM
ecletica-1329	68	10	17.09	17.09	NUM
ecletica-1329	68	11	were	be	AUX
ecletica-1329	68	12	set	set	VERB
ecletica-1329	68	13	for	for	ADP
ecletica-1329	68	14	4lrm	4lrm	PROPN
ecletica-1329	68	15	.	.	PUNCT
ecletica-1329	69	1	the	the	DET
ecletica-1329	69	2	prepared	prepare	VERB
ecletica-1329	69	3	ligands	ligand	NOUN
ecletica-1329	69	4	were	be	AUX
ecletica-1329	69	5	docked	dock	VERB
ecletica-1329	69	6	into	into	ADP
ecletica-1329	69	7	the	the	DET
ecletica-1329	69	8	binding	bind	VERB
ecletica-1329	69	9	site	site	NOUN
ecletica-1329	69	10	of	of	ADP
ecletica-1329	69	11	the	the	DET
ecletica-1329	69	12	receptor	receptor	NOUN
ecletica-1329	69	13	which	which	PRON
ecletica-1329	69	14	was	be	AUX
ecletica-1329	69	15	determined	determine	VERB
ecletica-1329	69	16	by	by	ADP
ecletica-1329	69	17	using	use	VERB
ecletica-1329	69	18	castp	castp	ADJ
ecletica-1329	69	19	online	online	ADJ
ecletica-1329	69	20	server	server	NOUN
ecletica-1329	69	21	)	)	PUNCT
ecletica-1329	69	22	and	and	CCONJ
ecletica-1329	69	23	the	the	DET
ecletica-1329	69	24	docking	docking	NOUN
ecletica-1329	69	25	calculation	calculation	NOUN
ecletica-1329	69	26	was	be	AUX
ecletica-1329	69	27	performed	perform	VERB
ecletica-1329	69	28	using	use	VERB
ecletica-1329	69	29	autodock	autodock	ADJ
ecletica-1329	69	30	vina	vina	NOUN
ecletica-1329	69	31	from	from	ADP
ecletica-1329	69	32	pyrx	pyrx	NOUN
ecletica-1329	69	33	workspace	workspace	NOUN
ecletica-1329	69	34	(	(	PUNCT
ecletica-1329	69	35	trott	trott	PROPN
ecletica-1329	69	36	and	and	CCONJ
ecletica-1329	69	37	olson	olson	NOUN
ecletica-1329	69	38	,	,	PUNCT
ecletica-1329	69	39	2010	2010	NUM
ecletica-1329	69	40	)	)	PUNCT
ecletica-1329	69	41	.	.	PUNCT
ecletica-1329	70	1	the	the	DET
ecletica-1329	70	2	inhibitors	inhibitor	NOUN
ecletica-1329	70	3	were	be	AUX
ecletica-1329	70	4	treated	treat	VERB
ecletica-1329	70	5	as	as	ADP
ecletica-1329	70	6	flexible	flexible	ADJ
ecletica-1329	70	7	throughout	throughout	ADP
ecletica-1329	70	8	the	the	DET
ecletica-1329	70	9	docking	docking	NOUN
ecletica-1329	70	10	simulations	simulation	NOUN
ecletica-1329	70	11	.	.	PUNCT
ecletica-1329	71	1	a	a	DET
ecletica-1329	71	2	forcefield	forcefield	NOUN
ecletica-1329	71	3	-	-	PUNCT
ecletica-1329	71	4	based	base	VERB
ecletica-1329	71	5	energy	energy	NOUN
ecletica-1329	71	6	scoring	scoring	NOUN
ecletica-1329	71	7	function	function	NOUN
ecletica-1329	71	8	was	be	AUX
ecletica-1329	71	9	used	use	VERB
ecletica-1329	71	10	to	to	PART
ecletica-1329	71	11	score	score	VERB
ecletica-1329	71	12	the	the	DET
ecletica-1329	71	13	ligand	ligand	ADJ
ecletica-1329	71	14	orientations	orientation	NOUN
ecletica-1329	71	15	,	,	PUNCT
ecletica-1329	71	16	and	and	CCONJ
ecletica-1329	71	17	the	the	DET
ecletica-1329	71	18	highest	highest	ADV
ecletica-1329	71	19	-	-	PUNCT
ecletica-1329	71	20	scoring	scoring	NOUN
ecletica-1329	71	21	binding	bind	VERB
ecletica-1329	71	22	structure	structure	NOUN
ecletica-1329	71	23	was	be	AUX
ecletica-1329	71	24	chosen	choose	VERB
ecletica-1329	71	25	.	.	PUNCT
ecletica-1329	72	1	finally	finally	ADV
ecletica-1329	72	2	,	,	PUNCT
ecletica-1329	72	3	3d	3d	NUM
ecletica-1329	72	4	views	view	NOUN
ecletica-1329	72	5	of	of	ADP
ecletica-1329	72	6	the	the	DET
ecletica-1329	72	7	proteinligand	proteinligand	ADJ
ecletica-1329	72	8	complex	complex	NOUN
ecletica-1329	72	9	were	be	AUX
ecletica-1329	72	10	analyzed	analyze	VERB
ecletica-1329	72	11	by	by	ADP
ecletica-1329	72	12	using	use	VERB
ecletica-1329	72	13	ucsf	ucsf	PROPN
ecletica-1329	72	14	chimera	chimera	PROPN
ecletica-1329	72	15	1.14	1.14	NUM
ecletica-1329	72	16	and	and	CCONJ
ecletica-1329	72	17	discovery	discovery	PROPN
ecletica-1329	72	18	studio	studio	NOUN
ecletica-1329	72	19	2020	2020	NUM
ecletica-1329	72	20	was	be	AUX
ecletica-1329	72	21	used	use	VERB
ecletica-1329	72	22	to	to	PART
ecletica-1329	72	23	create	create	VERB
ecletica-1329	72	24	the	the	DET
ecletica-1329	72	25	2d	2d	NUM
ecletica-1329	72	26	images	image	NOUN
ecletica-1329	72	27	of	of	ADP
ecletica-1329	72	28	the	the	DET
ecletica-1329	72	29	molecular	molecular	ADJ
ecletica-1329	72	30	interactions	interaction	NOUN
ecletica-1329	72	31	(	(	PUNCT
ecletica-1329	72	32	capra	capra	PROPN
ecletica-1329	72	33	et	et	PROPN
ecletica-1329	72	34	al	al	PROPN
ecletica-1329	72	35	.	.	PROPN
ecletica-1329	72	36	,	,	PUNCT
ecletica-1329	72	37	2009	2009	NUM
ecletica-1329	72	38	;	;	PUNCT
ecletica-1329	72	39	oyeneyin	oyeneyin	PROPN
ecletica-1329	72	40	et	et	PROPN
ecletica-1329	72	41	al	al	PROPN
ecletica-1329	72	42	.	.	PROPN
ecletica-1329	72	43	,	,	PUNCT
ecletica-1329	72	44	2022	2022	NUM
ecletica-1329	72	45	)	)	PUNCT
ecletica-1329	72	46	.	.	PUNCT
ecletica-1329	73	1	2.5	2.5	NUM
ecletica-1329	73	2	admet	admet	NOUN
ecletica-1329	73	3	screening	screen	VERB
ecletica-1329	73	4	the	the	DET
ecletica-1329	73	5	biological	biological	ADJ
ecletica-1329	73	6	action	action	NOUN
ecletica-1329	73	7	of	of	ADP
ecletica-1329	73	8	medications	medication	NOUN
ecletica-1329	73	9	and	and	CCONJ
ecletica-1329	73	10	their	their	PRON
ecletica-1329	73	11	metabolic	metabolic	NOUN
ecletica-1329	73	12	fate	fate	NOUN
ecletica-1329	73	13	in	in	ADP
ecletica-1329	73	14	an	an	DET
ecletica-1329	73	15	organism	organism	NOUN
ecletica-1329	73	16	are	be	AUX
ecletica-1329	73	17	intimately	intimately	ADV
ecletica-1329	73	18	related	relate	VERB
ecletica-1329	73	19	to	to	ADP
ecletica-1329	73	20	their	their	PRON
ecletica-1329	73	21	absorption	absorption	NOUN
ecletica-1329	73	22	,	,	PUNCT
ecletica-1329	73	23	distribution	distribution	NOUN
ecletica-1329	73	24	,	,	PUNCT
ecletica-1329	73	25	metabolism	metabolism	NOUN
ecletica-1329	73	26	,	,	PUNCT
ecletica-1329	73	27	and	and	CCONJ
ecletica-1329	73	28	excretion	excretion	NOUN
ecletica-1329	73	29	(	(	PUNCT
ecletica-1329	73	30	adme	adme	NOUN
ecletica-1329	73	31	)	)	PUNCT
ecletica-1329	73	32	and	and	CCONJ
ecletica-1329	73	33	toxicity	toxicity	NOUN
ecletica-1329	73	34	(	(	PUNCT
ecletica-1329	73	35	admet	admet	NOUN
ecletica-1329	73	36	)	)	PUNCT
ecletica-1329	73	37	qualities	quality	NOUN
ecletica-1329	73	38	.	.	PUNCT
ecletica-1329	74	1	in	in	ADP
ecletica-1329	74	2	silico	silico	NOUN
ecletica-1329	74	3	predictive	predictive	ADJ
ecletica-1329	74	4	models	model	NOUN
ecletica-1329	74	5	were	be	AUX
ecletica-1329	74	6	used	use	VERB
ecletica-1329	74	7	to	to	PART
ecletica-1329	74	8	determine	determine	VERB
ecletica-1329	74	9	the	the	DET
ecletica-1329	74	10	admet	admet	NOUN
ecletica-1329	74	11	properties	property	NOUN
ecletica-1329	74	12	of	of	ADP
ecletica-1329	74	13	the	the	DET
ecletica-1329	74	14	test	test	NOUN
ecletica-1329	74	15	substances	substance	NOUN
ecletica-1329	74	16	.	.	PUNCT
ecletica-1329	75	1	the	the	DET
ecletica-1329	75	2	adme	adme	NOUN
ecletica-1329	75	3	properties	property	NOUN
ecletica-1329	75	4	of	of	ADP
ecletica-1329	75	5	the	the	DET
ecletica-1329	75	6	substances	substance	NOUN
ecletica-1329	75	7	were	be	AUX
ecletica-1329	75	8	determined	determine	VERB
ecletica-1329	75	9	using	use	VERB
ecletica-1329	75	10	the	the	DET
ecletica-1329	75	11	swissadme	swissadme	NOUN
ecletica-1329	75	12	online	online	PROPN
ecletica-1329	75	13	server	server	PROPN
ecletica-1329	75	14	(	(	PUNCT
ecletica-1329	75	15	http://www.swissadme.ch/index.php/	http://www.swissadme.ch/index.php/	PROPN
ecletica-1329	75	16	)	)	PUNCT
ecletica-1329	75	17	(	(	PUNCT
ecletica-1329	75	18	daina	daina	PROPN
ecletica-1329	75	19	et	et	PROPN
ecletica-1329	75	20	al	al	PROPN
ecletica-1329	75	21	.	.	PROPN
ecletica-1329	75	22	,	,	PUNCT
ecletica-1329	75	23	2017	2017	NUM
ecletica-1329	75	24	)	)	PUNCT
ecletica-1329	75	25	.	.	PUNCT
ecletica-1329	76	1	the	the	DET
ecletica-1329	76	2	acute	acute	PROPN
ecletica-1329	76	3	toxicity	toxicity	NOUN
ecletica-1329	76	4	class	class	NOUN
ecletica-1329	76	5	,	,	PUNCT
ecletica-1329	76	6	ld50	ld50	PROPN
ecletica-1329	76	7	,	,	PUNCT
ecletica-1329	76	8	hepatotoxicity	hepatotoxicity	NOUN
ecletica-1329	76	9	,	,	PUNCT
ecletica-1329	76	10	carcinogenicity	carcinogenicity	NOUN
ecletica-1329	76	11	,	,	PUNCT
ecletica-1329	76	12	mutagenicity	mutagenicity	NOUN
ecletica-1329	76	13	,	,	PUNCT
ecletica-1329	76	14	cytotoxicity	cytotoxicity	NOUN
ecletica-1329	76	15	,	,	PUNCT
ecletica-1329	76	16	and	and	CCONJ
ecletica-1329	76	17	immunotoxicity	immunotoxicity	NOUN
ecletica-1329	76	18	of	of	ADP
ecletica-1329	76	19	the	the	DET
ecletica-1329	76	20	substances	substance	NOUN
ecletica-1329	76	21	were	be	AUX
ecletica-1329	76	22	all	all	PRON
ecletica-1329	76	23	predicted	predict	VERB
ecletica-1329	76	24	using	use	VERB
ecletica-1329	76	25	the	the	DET
ecletica-1329	76	26	protox	protox	NOUN
ecletica-1329	76	27	-	-	PUNCT
ecletica-1329	76	28	ii	ii	PROPN
ecletica-1329	76	29	web	web	NOUN
ecletica-1329	76	30	server	server	NOUN
ecletica-1329	76	31	(	(	PUNCT
ecletica-1329	76	32	banerjee	banerjee	PROPN
ecletica-1329	76	33	et	et	PROPN
ecletica-1329	76	34	al	al	PROPN
ecletica-1329	76	35	.	.	PROPN
ecletica-1329	76	36	,	,	PUNCT
ecletica-1329	76	37	2018	2018	NUM
ecletica-1329	76	38	)	)	PUNCT
ecletica-1329	76	39	.	.	PUNCT
ecletica-1329	77	1	the	the	DET
ecletica-1329	77	2	swiss	swiss	ADJ
ecletica-1329	77	3	adme	adme	NOUN
ecletica-1329	77	4	and	and	CCONJ
ecletica-1329	77	5	protox	protox	PROPN
ecletica-1329	77	6	-	-	PUNCT
ecletica-1329	77	7	ii	ii	NOUN
ecletica-1329	77	8	online	online	ADJ
ecletica-1329	77	9	servers	server	NOUN
ecletica-1329	77	10	take	take	VERB
ecletica-1329	77	11	one	one	NUM
ecletica-1329	77	12	or	or	CCONJ
ecletica-1329	77	13	more	more	ADJ
ecletica-1329	77	14	query	query	NOUN
ecletica-1329	77	15	molecules	molecule	NOUN
ecletica-1329	77	16	in	in	ADP
ecletica-1329	77	17	canonical	canonical	ADJ
ecletica-1329	77	18	smiles	smile	NOUN
ecletica-1329	77	19	format	format	NOUN
ecletica-1329	77	20	as	as	ADP
ecletica-1329	77	21	input	input	NOUN
ecletica-1329	77	22	and	and	CCONJ
ecletica-1329	77	23	use	use	VERB
ecletica-1329	77	24	a	a	DET
ecletica-1329	77	25	large	large	ADJ
ecletica-1329	77	26	database	database	NOUN
ecletica-1329	77	27	to	to	PART
ecletica-1329	77	28	accurately	accurately	ADV
ecletica-1329	77	29	predict	predict	VERB
ecletica-1329	77	30	the	the	DET
ecletica-1329	77	31	physicochemical	physicochemical	ADJ
ecletica-1329	77	32	properties	property	NOUN
ecletica-1329	77	33	,	,	PUNCT
ecletica-1329	77	34	pharmacokinetics	pharmacokinetic	NOUN
ecletica-1329	77	35	,	,	PUNCT
ecletica-1329	77	36	solubility	solubility	NOUN
ecletica-1329	77	37	,	,	PUNCT
ecletica-1329	77	38	lipophilicity	lipophilicity	NOUN
ecletica-1329	77	39	,	,	PUNCT
ecletica-1329	77	40	druglikeness	druglikeness	NOUN
ecletica-1329	77	41	,	,	PUNCT
ecletica-1329	77	42	bioavailability	bioavailability	NOUN
ecletica-1329	77	43	score	score	NOUN
ecletica-1329	77	44	,	,	PUNCT
ecletica-1329	77	45	therapeutic	therapeutic	ADJ
ecletica-1329	77	46	properties	property	NOUN
ecletica-1329	77	47	,	,	PUNCT
ecletica-1329	77	48	and	and	CCONJ
ecletica-1329	77	49	toxicity	toxicity	NOUN
ecletica-1329	77	50	of	of	ADP
ecletica-1329	77	51	compounds	compound	NOUN
ecletica-1329	77	52	.	.	PUNCT
ecletica-1329	78	1	3	3	X
ecletica-1329	78	2	.	.	NOUN
ecletica-1329	78	3	results	result	NOUN
ecletica-1329	78	4	and	and	CCONJ
ecletica-1329	78	5	discussion	discussion	NOUN
ecletica-1329	78	6	3.1	3.1	NUM
ecletica-1329	78	7	calculated	calculate	VERB
ecletica-1329	78	8	descriptors	descriptor	NOUN
ecletica-1329	78	9	the	the	DET
ecletica-1329	78	10	calculated	calculate	VERB
ecletica-1329	78	11	descriptors	descriptor	NOUN
ecletica-1329	78	12	from	from	ADP
ecletica-1329	78	13	optimized	optimize	VERB
ecletica-1329	78	14	compounds	compound	NOUN
ecletica-1329	78	15	were	be	AUX
ecletica-1329	78	16	screened	screen	VERB
ecletica-1329	78	17	and	and	CCONJ
ecletica-1329	78	18	for	for	ADP
ecletica-1329	78	19	further	further	ADJ
ecletica-1329	78	20	processing	processing	NOUN
ecletica-1329	78	21	.	.	PUNCT
ecletica-1329	79	1	the	the	DET
ecletica-1329	79	2	calculated	calculate	VERB
ecletica-1329	79	3	descriptors	descriptor	NOUN
ecletica-1329	79	4	were	be	AUX
ecletica-1329	79	5	the	the	DET
ecletica-1329	79	6	energy	energy	NOUN
ecletica-1329	79	7	of	of	ADP
ecletica-1329	79	8	the	the	DET
ecletica-1329	79	9	highest	high	ADJ
ecletica-1329	79	10	occupied	occupy	VERB
ecletica-1329	79	11	molecular	molecular	ADJ
ecletica-1329	79	12	orbital	orbital	ADJ
ecletica-1329	79	13	(	(	PUNCT
ecletica-1329	79	14	ehomo	ehomo	ADJ
ecletica-1329	79	15	)	)	PUNCT
ecletica-1329	79	16	,	,	PUNCT
ecletica-1329	79	17	lowest	low	ADJ
ecletica-1329	79	18	unoccupied	unoccupied	ADJ
ecletica-1329	79	19	https://revista.iq.unesp.br/index.php/ecletica	https://revista.iq.unesp.br/index.php/ecletica	NOUN
ecletica-1329	79	20	https://doi.org/10.26850/1678-4618eqj.v48.1.2023.p55-71	https://doi.org/10.26850/1678-4618eqj.v48.1.2023.p55-71	PROPN
ecletica-1329	79	21	original	original	ADJ
ecletica-1329	79	22	article	article	NOUN
ecletica-1329	79	23	revista.iq.unesp.br	revista.iq.unesp.br	PROPN
ecletica-1329	79	24	61	61	NUM
ecletica-1329	79	25	eclética	eclética	PROPN
ecletica-1329	79	26	química	química	PROPN
ecletica-1329	79	27	,	,	PUNCT
ecletica-1329	79	28	vol	vol	NOUN
ecletica-1329	79	29	.	.	PROPN
ecletica-1329	79	30	48	48	NUM
ecletica-1329	79	31	,	,	PUNCT
ecletica-1329	79	32	n.	n.	NOUN
ecletica-1329	79	33	1	1	NUM
ecletica-1329	79	34	,	,	PUNCT
ecletica-1329	79	35	2023	2023	NUM
ecletica-1329	79	36	,	,	PUNCT
ecletica-1329	79	37	55	55	NUM
ecletica-1329	79	38	-	-	SYM
ecletica-1329	79	39	71	71	NUM
ecletica-1329	79	40	issn	issn	NOUN
ecletica-1329	79	41	:	:	PUNCT
ecletica-1329	79	42	1678	1678	NUM
ecletica-1329	79	43	-	-	SYM
ecletica-1329	79	44	4618	4618	NUM
ecletica-1329	79	45	doi	doi	NOUN
ecletica-1329	79	46	:	:	PUNCT
ecletica-1329	79	47	10.26850/1678	10.26850/1678	NUM
ecletica-1329	79	48	-	-	PUNCT
ecletica-1329	79	49	4618eqj.v48.1.2023.p55	4618eqj.v48.1.2023.p55	NUM
ecletica-1329	79	50	-	-	PUNCT
ecletica-1329	79	51	71	71	NUM
ecletica-1329	79	52	molecular	molecular	ADJ
ecletica-1329	79	53	orbital	orbital	ADJ
ecletica-1329	79	54	energy	energy	NOUN
ecletica-1329	79	55	(	(	PUNCT
ecletica-1329	79	56	elumo	elumo	ADJ
ecletica-1329	79	57	)	)	PUNCT
ecletica-1329	79	58	,	,	PUNCT
ecletica-1329	79	59	dipole	dipole	NOUN
ecletica-1329	79	60	moment	moment	NOUN
ecletica-1329	79	61	(	(	PUNCT
ecletica-1329	79	62	dm	dm	NOUN
ecletica-1329	79	63	)	)	PUNCT
ecletica-1329	79	64	,	,	PUNCT
ecletica-1329	79	65	volume	volume	NOUN
ecletica-1329	79	66	,	,	PUNCT
ecletica-1329	79	67	area	area	NOUN
ecletica-1329	79	68	,	,	PUNCT
ecletica-1329	79	69	lipophilicity	lipophilicity	NOUN
ecletica-1329	79	70	(	(	PUNCT
ecletica-1329	79	71	log	log	VERB
ecletica-1329	79	72	p	p	NOUN
ecletica-1329	79	73	)	)	PUNCT
ecletica-1329	79	74	,	,	PUNCT
ecletica-1329	79	75	polar	polar	ADJ
ecletica-1329	79	76	surface	surface	NOUN
ecletica-1329	79	77	area	area	NOUN
ecletica-1329	79	78	(	(	PUNCT
ecletica-1329	79	79	psa	psa	NOUN
ecletica-1329	79	80	)	)	PUNCT
ecletica-1329	79	81	,	,	PUNCT
ecletica-1329	79	82	number	number	NOUN
ecletica-1329	79	83	of	of	ADP
ecletica-1329	79	84	hydrogen	hydrogen	NOUN
ecletica-1329	79	85	bond	bond	NOUN
ecletica-1329	79	86	donor	donor	NOUN
ecletica-1329	79	87	(	(	PUNCT
ecletica-1329	79	88	hbd	hbd	PROPN
ecletica-1329	79	89	)	)	PUNCT
ecletica-1329	79	90	,	,	PUNCT
ecletica-1329	79	91	hydrogen	hydrogen	NOUN
ecletica-1329	79	92	bond	bond	NOUN
ecletica-1329	79	93	acceptor	acceptor	NOUN
ecletica-1329	79	94	(	(	PUNCT
ecletica-1329	79	95	hba	hba	NOUN
ecletica-1329	79	96	)	)	PUNCT
ecletica-1329	79	97	.	.	PUNCT
ecletica-1329	80	1	the	the	DET
ecletica-1329	80	2	calculated	calculate	VERB
ecletica-1329	80	3	descriptors	descriptor	NOUN
ecletica-1329	80	4	also	also	ADV
ecletica-1329	80	5	helped	help	VERB
ecletica-1329	80	6	in	in	ADP
ecletica-1329	80	7	qsar	qsar	NOUN
ecletica-1329	80	8	study	study	NOUN
ecletica-1329	80	9	.	.	PUNCT
ecletica-1329	81	1	as	as	SCONJ
ecletica-1329	81	2	shown	show	VERB
ecletica-1329	81	3	in	in	ADP
ecletica-1329	81	4	table	table	NOUN
ecletica-1329	81	5	2	2	NUM
ecletica-1329	81	6	,	,	PUNCT
ecletica-1329	81	7	c3	c3	PROPN
ecletica-1329	81	8	possess	possess	VERB
ecletica-1329	81	9	higher	high	ADJ
ecletica-1329	81	10	ehomo	ehomo	ADJ
ecletica-1329	81	11	value	value	NOUN
ecletica-1329	81	12	and	and	CCONJ
ecletica-1329	81	13	according	accord	VERB
ecletica-1329	81	14	to	to	ADP
ecletica-1329	81	15	report	report	NOUN
ecletica-1329	81	16	by	by	ADP
ecletica-1329	81	17	semire	semire	NOUN
ecletica-1329	81	18	et	et	PROPN
ecletica-1329	81	19	al	al	PROPN
ecletica-1329	81	20	.	.	PROPN
ecletica-1329	82	1	(	(	PUNCT
ecletica-1329	82	2	2017	2017	NUM
ecletica-1329	82	3	)	)	PUNCT
ecletica-1329	82	4	,	,	PUNCT
ecletica-1329	82	5	compound	compound	VERB
ecletica-1329	82	6	with	with	ADP
ecletica-1329	82	7	high	high	ADJ
ecletica-1329	82	8	ehomo	ehomo	ADJ
ecletica-1329	82	9	value	value	NOUN
ecletica-1329	82	10	possess	possess	VERB
ecletica-1329	82	11	greater	great	ADJ
ecletica-1329	82	12	tendency	tendency	NOUN
ecletica-1329	82	13	to	to	PART
ecletica-1329	82	14	donate	donate	VERB
ecletica-1329	82	15	electron	electron	NOUN
ecletica-1329	82	16	to	to	ADP
ecletica-1329	82	17	the	the	DET
ecletica-1329	82	18	neighboring	neighboring	NOUN
ecletica-1329	82	19	compounds	compound	NOUN
ecletica-1329	82	20	and	and	CCONJ
ecletica-1329	82	21	it	it	PRON
ecletica-1329	82	22	is	be	AUX
ecletica-1329	82	23	expected	expect	VERB
ecletica-1329	82	24	to	to	PART
ecletica-1329	82	25	interact	interact	VERB
ecletica-1329	82	26	with	with	ADP
ecletica-1329	82	27	the	the	DET
ecletica-1329	82	28	target	target	NOUN
ecletica-1329	82	29	;	;	PUNCT
ecletica-1329	82	30	therefore	therefore	ADV
ecletica-1329	82	31	,	,	PUNCT
ecletica-1329	82	32	c3	c3	PROPN
ecletica-1329	82	33	with	with	ADP
ecletica-1329	82	34	–	–	PUNCT
ecletica-1329	82	35	4.29	4.29	NUM
ecletica-1329	82	36	ev	ev	NOUN
ecletica-1329	82	37	is	be	AUX
ecletica-1329	82	38	expected	expect	VERB
ecletica-1329	82	39	to	to	PART
ecletica-1329	82	40	interact	interact	VERB
ecletica-1329	82	41	well	well	ADV
ecletica-1329	82	42	with	with	ADP
ecletica-1329	82	43	neighboring	neighboring	NOUN
ecletica-1329	82	44	compounds	compound	NOUN
ecletica-1329	82	45	.	.	PUNCT
ecletica-1329	83	1	as	as	SCONJ
ecletica-1329	83	2	reported	report	VERB
ecletica-1329	83	3	by	by	ADP
ecletica-1329	83	4	oyebamiji	oyebamiji	NOUN
ecletica-1329	83	5	et	et	PROPN
ecletica-1329	83	6	al	al	PROPN
ecletica-1329	83	7	.	.	PROPN
ecletica-1329	84	1	(	(	PUNCT
ecletica-1329	84	2	2018	2018	NUM
ecletica-1329	84	3	)	)	PUNCT
ecletica-1329	84	4	,	,	PUNCT
ecletica-1329	84	5	the	the	PRON
ecletica-1329	84	6	lower	low	ADJ
ecletica-1329	84	7	the	the	DET
ecletica-1329	84	8	elumo	elumo	ADJ
ecletica-1329	84	9	value	value	NOUN
ecletica-1329	84	10	the	the	PRON
ecletica-1329	84	11	better	well	ADJ
ecletica-1329	84	12	the	the	DET
ecletica-1329	84	13	tendency	tendency	NOUN
ecletica-1329	84	14	of	of	ADP
ecletica-1329	84	15	the	the	DET
ecletica-1329	84	16	compound	compound	NOUN
ecletica-1329	84	17	to	to	PART
ecletica-1329	84	18	interact	interact	VERB
ecletica-1329	84	19	with	with	ADP
ecletica-1329	84	20	the	the	DET
ecletica-1329	84	21	target	target	NOUN
ecletica-1329	84	22	;	;	PUNCT
ecletica-1329	84	23	therefore	therefore	ADV
ecletica-1329	84	24	,	,	PUNCT
ecletica-1329	84	25	c8	c8	PROPN
ecletica-1329	84	26	proved	prove	VERB
ecletica-1329	84	27	to	to	PART
ecletica-1329	84	28	have	have	VERB
ecletica-1329	84	29	a	a	DET
ecletica-1329	84	30	tendency	tendency	NOUN
ecletica-1329	84	31	to	to	PART
ecletica-1329	84	32	interact	interact	VERB
ecletica-1329	84	33	than	than	ADP
ecletica-1329	84	34	other	other	ADJ
ecletica-1329	84	35	studied	study	VERB
ecletica-1329	84	36	compounds	compound	NOUN
ecletica-1329	84	37	(	(	PUNCT
ecletica-1329	84	38	table	table	NOUN
ecletica-1329	84	39	2	2	NUM
ecletica-1329	84	40	)	)	PUNCT
ecletica-1329	84	41	.	.	PUNCT
ecletica-1329	85	1	table	table	NOUN
ecletica-1329	85	2	2	2	NUM
ecletica-1329	85	3	.	.	NUM
ecletica-1329	85	4	selected	select	VERB
ecletica-1329	85	5	descriptors	descriptor	NOUN
ecletica-1329	85	6	for	for	ADP
ecletica-1329	85	7	the	the	DET
ecletica-1329	85	8	qsar	qsar	NOUN
ecletica-1329	85	9	model	model	NOUN
ecletica-1329	85	10	.	.	PUNCT
ecletica-1329	86	1	ehomo	ehomo	PROPN
ecletica-1329	86	2	ev	ev	PROPN
ecletica-1329	86	3	elumo	elumo	PROPN
ecletica-1329	86	4	ev	ev	X
ecletica-1329	86	5	dm	dm	PROPN
ecletica-1329	86	6	debye	debye	PROPN
ecletica-1329	86	7	mw	mw	PROPN
ecletica-1329	86	8	area	area	PROPN
ecletica-1329	86	9	vol	vol	NOUN
ecletica-1329	86	10	psa	psa	NOUN
ecletica-1329	86	11	log	log	PROPN
ecletica-1329	86	12	p	p	PROPN
ecletica-1329	86	13	pol	pol	PROPN
ecletica-1329	86	14	hbd	hbd	PROPN
ecletica-1329	86	15	hba	hba	PROPN
ecletica-1329	86	16	c1	c1	PROPN
ecletica-1329	86	17	–	–	PUNCT
ecletica-1329	86	18	5.27	5.27	NUM
ecletica-1329	86	19	–	–	PUNCT
ecletica-1329	86	20	2.24	2.24	NUM
ecletica-1329	86	21	7.73	7.73	NUM
ecletica-1329	86	22	328.8	328.8	NUM
ecletica-1329	87	1	339.08	339.08	NUM
ecletica-1329	87	2	322.96	322.96	NUM
ecletica-1329	87	3	36.526	36.526	NUM
ecletica-1329	87	4	1.24	1.24	NUM
ecletica-1329	87	5	66.86	66.86	NUM
ecletica-1329	87	6	0	0	NUM
ecletica-1329	87	7	4	4	NUM
ecletica-1329	87	8	c2	c2	PROPN
ecletica-1329	87	9	–	–	PUNCT
ecletica-1329	87	10	5.03	5.03	NUM
ecletica-1329	87	11	–	–	PUNCT
ecletica-1329	87	12	1.31	1.31	NUM
ecletica-1329	87	13	11.48	11.48	NUM
ecletica-1329	87	14	324.38	324.38	NUM
ecletica-1329	87	15	340.27	340.27	NUM
ecletica-1329	87	16	325.26	325.26	NUM
ecletica-1329	87	17	67.428	67.428	NUM
ecletica-1329	87	18	–	–	PUNCT
ecletica-1329	87	19	0.16	0.16	NUM
ecletica-1329	87	20	66.88	66.88	NUM
ecletica-1329	87	21	2	2	NUM
ecletica-1329	87	22	6	6	NUM
ecletica-1329	87	23	c3	c3	NOUN
ecletica-1329	87	24	–	–	PUNCT
ecletica-1329	87	25	4.29	4.29	NUM
ecletica-1329	87	26	–	–	PUNCT
ecletica-1329	87	27	1.99	1.99	NUM
ecletica-1329	87	28	6.56	6.56	NUM
ecletica-1329	87	29	455.56	455.56	NUM
ecletica-1329	87	30	492.87	492.87	NUM
ecletica-1329	87	31	474.59	474.59	NUM
ecletica-1329	87	32	54.06	54.06	NUM
ecletica-1329	87	33	0.66	0.66	NUM
ecletica-1329	87	34	79.33	79.33	NUM
ecletica-1329	87	35	1	1	NUM
ecletica-1329	87	36	7	7	NUM
ecletica-1329	87	37	c4	c4	NOUN
ecletica-1329	87	38	–	–	PUNCT
ecletica-1329	87	39	6.05	6.05	NUM
ecletica-1329	87	40	–	–	PUNCT
ecletica-1329	87	41	1.99	1.99	NUM
ecletica-1329	87	42	3.39	3.39	NUM
ecletica-1329	87	43	481.38	481.38	NUM
ecletica-1329	87	44	471.57	471.57	NUM
ecletica-1329	87	45	452.07	452.07	NUM
ecletica-1329	87	46	52.682	52.682	NUM
ecletica-1329	87	47	1.12	1.12	NUM
ecletica-1329	87	48	77.09	77.09	NUM
ecletica-1329	87	49	1	1	NUM
ecletica-1329	87	50	6	6	NUM
ecletica-1329	87	51	c5	c5	PROPN
ecletica-1329	87	52	–	–	PUNCT
ecletica-1329	87	53	5.93	5.93	NUM
ecletica-1329	87	54	–	–	PUNCT
ecletica-1329	87	55	1.78	1.78	NUM
ecletica-1329	87	56	3.43	3.43	NUM
ecletica-1329	87	57	426.5	426.5	NUM
ecletica-1329	87	58	461.31	461.31	NUM
ecletica-1329	87	59	43.34	43.34	NUM
ecletica-1329	87	60	52.55	52.55	NUM
ecletica-1329	87	61	1.66	1.66	NUM
ecletica-1329	87	62	76.36	76.36	NUM
ecletica-1329	87	63	1	1	NUM
ecletica-1329	87	64	6	6	NUM
ecletica-1329	87	65	c6	c6	NOUN
ecletica-1329	87	66	–	–	PUNCT
ecletica-1329	87	67	5.94	5.94	NUM
ecletica-1329	87	68	–	–	PUNCT
ecletica-1329	87	69	2.54	2.54	NUM
ecletica-1329	87	70	8.35	8.35	NUM
ecletica-1329	87	71	453.5	453.5	NUM
ecletica-1329	87	72	453.91	453.91	NUM
ecletica-1329	87	73	445.24	445.24	NUM
ecletica-1329	87	74	79.11	79.11	NUM
ecletica-1329	87	75	0.56	0.56	NUM
ecletica-1329	87	76	76.69	76.69	NUM
ecletica-1329	87	77	2	2	NUM
ecletica-1329	87	78	8	8	NUM
ecletica-1329	87	79	c7	c7	NOUN
ecletica-1329	87	80	–	–	PUNCT
ecletica-1329	87	81	5.86	5.86	NUM
ecletica-1329	87	82	–	–	PUNCT
ecletica-1329	87	83	2.91	2.91	NUM
ecletica-1329	87	84	9.09	9.09	NUM
ecletica-1329	87	85	487.94	487.94	NUM
ecletica-1329	87	86	467.07	467.07	NUM
ecletica-1329	87	87	459.43	459.43	NUM
ecletica-1329	87	88	79.3	79.3	NUM
ecletica-1329	87	89	0.42	0.42	NUM
ecletica-1329	87	90	77.95	77.95	NUM
ecletica-1329	87	91	2	2	NUM
ecletica-1329	87	92	8	8	NUM
ecletica-1329	87	93	c8	c8	NOUN
ecletica-1329	87	94	–	–	PUNCT
ecletica-1329	87	95	6.12	6.12	NUM
ecletica-1329	87	96	–	–	PUNCT
ecletica-1329	87	97	3.78	3.78	NUM
ecletica-1329	87	98	5.63	5.63	NUM
ecletica-1329	87	99	532.4	532.4	NUM
ecletica-1329	87	100	475.79	475.79	NUM
ecletica-1329	87	101	465.79	465.79	NUM
ecletica-1329	87	102	80.499	80.499	NUM
ecletica-1329	87	103	0.69	0.69	NUM
ecletica-1329	87	104	78.61	78.61	NUM
ecletica-1329	87	105	2	2	NUM
ecletica-1329	87	106	8	8	NUM
ecletica-1329	87	107	c9	c9	NOUN
ecletica-1329	87	108	–	–	PUNCT
ecletica-1329	87	109	6.35	6.35	NUM
ecletica-1329	87	110	–	–	PUNCT
ecletica-1329	87	111	1.67	1.67	NUM
ecletica-1329	87	112	8.61	8.61	NUM
ecletica-1329	87	113	396.44	396.44	NUM
ecletica-1329	87	114	430.16	430.16	NUM
ecletica-1329	87	115	404.16	404.16	NUM
ecletica-1329	87	116	62.633	62.633	NUM
ecletica-1329	87	117	0.64	0.64	NUM
ecletica-1329	87	118	73.05	73.05	NUM
ecletica-1329	87	119	0	0	NUM
ecletica-1329	87	120	6	6	NUM
ecletica-1329	87	121	c10	c10	VERB
ecletica-1329	87	122	–	–	PUNCT
ecletica-1329	87	123	6.35	6.35	NUM
ecletica-1329	87	124	–	–	PUNCT
ecletica-1329	87	125	1.66	1.66	NUM
ecletica-1329	87	126	9.72	9.72	NUM
ecletica-1329	87	127	382.42	382.42	NUM
ecletica-1329	87	128	407.97	407.97	NUM
ecletica-1329	87	129	380.79	380.79	NUM
ecletica-1329	87	130	98.07	98.07	NUM
ecletica-1329	87	131	–	–	PUNCT
ecletica-1329	87	132	0.86	0.86	NUM
ecletica-1329	87	133	71.15	71.15	NUM
ecletica-1329	87	134	2	2	NUM
ecletica-1329	87	135	8	8	NUM
ecletica-1329	87	136	c11	c11	NOUN
ecletica-1329	87	137	–	–	PUNCT
ecletica-1329	87	138	6.09	6.09	NUM
ecletica-1329	87	139	–	–	PUNCT
ecletica-1329	87	140	1.68	1.68	NUM
ecletica-1329	87	141	8.6	8.6	NUM
ecletica-1329	87	142	484.56	484.56	NUM
ecletica-1329	87	143	524.08	524.08	NUM
ecletica-1329	87	144	498.26	498.26	NUM
ecletica-1329	87	145	77.218	77.218	NUM
ecletica-1329	87	146	2.3	2.3	NUM
ecletica-1329	87	147	80.75	80.75	NUM
ecletica-1329	87	148	1	1	NUM
ecletica-1329	87	149	8	8	NUM
ecletica-1329	87	150	c12	c12	NOUN
ecletica-1329	87	151	–	–	PUNCT
ecletica-1329	87	152	5.93	5.93	NUM
ecletica-1329	87	153	–	–	PUNCT
ecletica-1329	87	154	2.25	2.25	NUM
ecletica-1329	87	155	13.74	13.74	NUM
ecletica-1329	87	156	511.54	511.54	NUM
ecletica-1329	87	157	523.44	523.44	NUM
ecletica-1329	87	158	501.31	501.31	NUM
ecletica-1329	87	159	98.47	98.47	NUM
ecletica-1329	87	160	–	–	PUNCT
ecletica-1329	87	161	0.37	0.37	NUM
ecletica-1329	87	162	81.17	81.17	NUM
ecletica-1329	87	163	2	2	NUM
ecletica-1329	87	164	10	10	NUM
ecletica-1329	87	165	c13	c13	NOUN
ecletica-1329	87	166	–	–	PUNCT
ecletica-1329	87	167	5.92	5.92	NUM
ecletica-1329	87	168	–	–	PUNCT
ecletica-1329	87	169	2.38	2.38	NUM
ecletica-1329	87	170	11.48	11.48	NUM
ecletica-1329	87	171	545.98	545.98	NUM
ecletica-1329	87	172	533.57	533.57	NUM
ecletica-1329	87	173	514.42	514.42	NUM
ecletica-1329	87	174	95.51	95.51	NUM
ecletica-1329	87	175	–	–	PUNCT
ecletica-1329	87	176	0.51	0.51	NUM
ecletica-1329	87	177	82.27	82.27	NUM
ecletica-1329	87	178	2	2	NUM
ecletica-1329	87	179	10	10	NUM
ecletica-1329	87	180	c14	c14	NOUN
ecletica-1329	87	181	–	–	PUNCT
ecletica-1329	87	182	5.91	5.91	NUM
ecletica-1329	87	183	–	–	PUNCT
ecletica-1329	87	184	2.39	2.39	NUM
ecletica-1329	87	185	11.62	11.62	NUM
ecletica-1329	87	186	590.43	590.43	NUM
ecletica-1329	87	187	536.62	536.62	NUM
ecletica-1329	87	188	518.51	518.51	NUM
ecletica-1329	87	189	94.66	94.66	NUM
ecletica-1329	87	190	–	–	PUNCT
ecletica-1329	87	191	0.24	0.24	NUM
ecletica-1329	87	192	82.6	82.6	NUM
ecletica-1329	87	193	2	2	NUM
ecletica-1329	87	194	10	10	NUM
ecletica-1329	87	195	dm	dm	NOUN
ecletica-1329	87	196	:	:	PUNCT
ecletica-1329	87	197	dipole	dipole	NOUN
ecletica-1329	87	198	moment	moment	NOUN
ecletica-1329	87	199	;	;	PUNCT
ecletica-1329	87	200	mw	mw	X
ecletica-1329	87	201	:	:	PUNCT
ecletica-1329	87	202	molecular	molecular	ADJ
ecletica-1329	87	203	weight	weight	NOUN
ecletica-1329	87	204	;	;	PUNCT
ecletica-1329	87	205	vol	vol	NOUN
ecletica-1329	87	206	:	:	PUNCT
ecletica-1329	87	207	volume	volume	NOUN
ecletica-1329	87	208	;	;	PUNCT
ecletica-1329	87	209	psa	psa	VERB
ecletica-1329	87	210	:	:	PUNCT
ecletica-1329	87	211	polar	polar	ADJ
ecletica-1329	87	212	surface	surface	NOUN
ecletica-1329	87	213	area	area	NOUN
ecletica-1329	87	214	;	;	PUNCT
ecletica-1329	87	215	pol	pol	NOUN
ecletica-1329	87	216	:	:	PUNCT
ecletica-1329	87	217	polarizability	polarizability	NOUN
ecletica-1329	87	218	;	;	PUNCT
ecletica-1329	87	219	hbd	hbd	NOUN
ecletica-1329	87	220	:	:	PUNCT
ecletica-1329	87	221	hydrogen	hydrogen	NOUN
ecletica-1329	87	222	bond	bond	NOUN
ecletica-1329	87	223	donor	donor	NOUN
ecletica-1329	87	224	and	and	CCONJ
ecletica-1329	87	225	hba	hba	NOUN
ecletica-1329	87	226	:	:	PUNCT
ecletica-1329	87	227	hydrogen	hydrogen	NOUN
ecletica-1329	87	228	bond	bond	NOUN
ecletica-1329	87	229	acceptor	acceptor	NOUN
ecletica-1329	87	230	.	.	PUNCT
ecletica-1329	88	1	3.2	3.2	NUM
ecletica-1329	88	2	qsar	qsar	NOUN
ecletica-1329	88	3	study	study	NOUN
ecletica-1329	88	4	five	five	NUM
ecletica-1329	88	5	distinct	distinct	ADJ
ecletica-1329	88	6	models	model	NOUN
ecletica-1329	88	7	were	be	AUX
ecletica-1329	88	8	developed	develop	VERB
ecletica-1329	88	9	and	and	CCONJ
ecletica-1329	88	10	the	the	DET
ecletica-1329	88	11	best	good	ADJ
ecletica-1329	88	12	model	model	NOUN
ecletica-1329	88	13	was	be	AUX
ecletica-1329	88	14	chosen	choose	VERB
ecletica-1329	88	15	and	and	CCONJ
ecletica-1329	88	16	reported	report	VERB
ecletica-1329	88	17	among	among	ADP
ecletica-1329	88	18	them	they	PRON
ecletica-1329	88	19	,	,	PUNCT
ecletica-1329	88	20	since	since	SCONJ
ecletica-1329	88	21	it	it	PRON
ecletica-1329	88	22	met	meet	VERB
ecletica-1329	88	23	the	the	DET
ecletica-1329	88	24	minimum	minimum	ADJ
ecletica-1329	88	25	conditions	condition	NOUN
ecletica-1329	88	26	for	for	ADP
ecletica-1329	88	27	the	the	DET
ecletica-1329	88	28	evaluation	evaluation	NOUN
ecletica-1329	88	29	of	of	ADP
ecletica-1329	88	30	a	a	DET
ecletica-1329	88	31	valid	valid	ADJ
ecletica-1329	88	32	qsar	qsar	NOUN
ecletica-1329	88	33	model	model	NOUN
ecletica-1329	88	34	,	,	PUNCT
ecletica-1329	88	35	as	as	SCONJ
ecletica-1329	88	36	reported	report	VERB
ecletica-1329	88	37	by	by	ADP
ecletica-1329	88	38	veerasamy	veerasamy	NOUN
ecletica-1329	88	39	et	et	PROPN
ecletica-1329	88	40	al	al	PROPN
ecletica-1329	88	41	.	.	PROPN
ecletica-1329	89	1	(	(	PUNCT
ecletica-1329	89	2	2011	2011	NUM
ecletica-1329	89	3	)	)	PUNCT
ecletica-1329	89	4	.	.	PUNCT
ecletica-1329	90	1	tables	table	NOUN
ecletica-1329	90	2	2–5	2–5	PROPN
ecletica-1329	90	3	as	as	ADV
ecletica-1329	90	4	well	well	ADV
ecletica-1329	90	5	as	as	ADP
ecletica-1329	90	6	figs	fig	NOUN
ecletica-1329	90	7	.	.	PUNCT
ecletica-1329	91	1	1	1	NUM
ecletica-1329	91	2	and	and	CCONJ
ecletica-1329	91	3	2	2	NUM
ecletica-1329	91	4	present	present	VERB
ecletica-1329	91	5	the	the	DET
ecletica-1329	91	6	findings	finding	NOUN
ecletica-1329	91	7	of	of	ADP
ecletica-1329	91	8	the	the	DET
ecletica-1329	91	9	qsar	qsar	NOUN
ecletica-1329	91	10	study	study	NOUN
ecletica-1329	91	11	and	and	CCONJ
ecletica-1329	91	12	the	the	DET
ecletica-1329	91	13	developed	develop	VERB
ecletica-1329	91	14	qsar	qsar	NOUN
ecletica-1329	91	15	model	model	NOUN
ecletica-1329	91	16	was	be	AUX
ecletica-1329	91	17	presented	present	VERB
ecletica-1329	91	18	in	in	ADP
ecletica-1329	91	19	eq	eq	ADP
ecletica-1329	91	20	.	.	PROPN
ecletica-1329	91	21	4	4	X
ecletica-1329	91	22	.	.	X
ecletica-1329	92	1	the	the	DET
ecletica-1329	92	2	selected	select	VERB
ecletica-1329	92	3	and	and	CCONJ
ecletica-1329	92	4	reported	report	VERB
ecletica-1329	92	5	model	model	NOUN
ecletica-1329	92	6	is	be	AUX
ecletica-1329	92	7	given	give	VERB
ecletica-1329	92	8	by	by	ADP
ecletica-1329	92	9	the	the	DET
ecletica-1329	92	10	eq	eq	NOUN
ecletica-1329	92	11	.	.	PROPN
ecletica-1329	92	12	4	4	NUM
ecletica-1329	92	13	with	with	ADP
ecletica-1329	92	14	the	the	DET
ecletica-1329	92	15	following	follow	VERB
ecletica-1329	92	16	validation	validation	NOUN
ecletica-1329	92	17	terms	term	NOUN
ecletica-1329	92	18	:	:	PUNCT
ecletica-1329	92	19	r2	r2	PROPN
ecletica-1329	92	20	=	=	SYM
ecletica-1329	92	21	0.9525	0.9525	NUM
ecletica-1329	92	22	,	,	PUNCT
ecletica-1329	92	23	adj.r2	adj.r2	NOUN
ecletica-1329	92	24	=	=	NOUN
ecletica-1329	92	25	0.9314	0.9314	NUM
ecletica-1329	92	26	and	and	CCONJ
ecletica-1329	92	27	cv.r2	cv.r2	NOUN
ecletica-1329	92	28	=	=	ADJ
ecletica-1329	92	29	0.9719	0.9719	NUM
ecletica-1329	92	30	.	.	PUNCT
ecletica-1329	92	31	predicted	predict	VERB
ecletica-1329	92	32	ic50=179.0741	ic50=179.0741	PROPN
ecletica-1329	92	33	+	+	PROPN
ecletica-1329	92	34	6.54433	6.54433	NUM
ecletica-1329	92	35	(	(	PUNCT
ecletica-1329	92	36	dm	dm	NOUN
ecletica-1329	92	37	)	)	PUNCT
ecletica-1329	92	38	-5.73413	-5.73413	NOUN
ecletica-1329	92	39	(	(	PUNCT
ecletica-1329	92	40	log	log	VERB
ecletica-1329	92	41	p	p	X
ecletica-1329	92	42	)	)	PUNCT
ecletica-1329	92	43	-28.2133	-28.2133	PUNCT
ecletica-1329	92	44	(	(	PUNCT
ecletica-1329	92	45	hba	hba	NOUN
ecletica-1329	92	46	)	)	PUNCT
ecletica-1329	93	1	+	+	NUM
ecletica-1329	94	1	0.215819	0.215819	NUM
ecletica-1329	94	2	(	(	PUNCT
ecletica-1329	94	3	mw	mw	NOUN
ecletica-1329	94	4	)	)	PUNCT
ecletica-1329	94	5	(	(	PUNCT
ecletica-1329	94	6	4	4	X
ecletica-1329	94	7	)	)	PUNCT
ecletica-1329	94	8	figure	figure	NOUN
ecletica-1329	94	9	1	1	NUM
ecletica-1329	94	10	.	.	PUNCT
ecletica-1329	94	11	scatter	scatter	NOUN
ecletica-1329	94	12	plot	plot	NOUN
ecletica-1329	94	13	of	of	ADP
ecletica-1329	94	14	predicted	predict	VERB
ecletica-1329	94	15	ic50	ic50	PROPN
ecletica-1329	94	16	versus	versus	ADP
ecletica-1329	94	17	the	the	DET
ecletica-1329	94	18	experimental	experimental	ADJ
ecletica-1329	94	19	ic50	ic50	PROPN
ecletica-1329	94	20	for	for	ADP
ecletica-1329	94	21	the	the	DET
ecletica-1329	94	22	reported	report	VERB
ecletica-1329	94	23	model	model	NOUN
ecletica-1329	94	24	.	.	PUNCT
ecletica-1329	95	1	figure	figure	NOUN
ecletica-1329	95	2	2	2	NUM
ecletica-1329	95	3	.	.	PUNCT
ecletica-1329	95	4	scatter	scatter	NOUN
ecletica-1329	95	5	plot	plot	NOUN
ecletica-1329	95	6	of	of	ADP
ecletica-1329	95	7	residual	residual	ADJ
ecletica-1329	95	8	versus	versus	ADP
ecletica-1329	95	9	the	the	DET
ecletica-1329	95	10	experimental	experimental	ADJ
ecletica-1329	95	11	ic50	ic50	PROPN
ecletica-1329	95	12	for	for	ADP
ecletica-1329	95	13	the	the	DET
ecletica-1329	95	14	reported	report	VERB
ecletica-1329	95	15	model	model	NOUN
ecletica-1329	95	16	.	.	PUNCT
ecletica-1329	96	1	https://revista.iq.unesp.br/index.php/ecletica	https://revista.iq.unesp.br/index.php/ecletica	PROPN
ecletica-1329	96	2	https://doi.org/10.26850/1678-4618eqj.v48.1.2023.p55-71	https://doi.org/10.26850/1678-4618eqj.v48.1.2023.p55-71	PROPN
ecletica-1329	96	3	original	original	ADJ
ecletica-1329	96	4	article	article	NOUN
ecletica-1329	96	5	revista.iq.unesp.br	revista.iq.unesp.br	ADP
ecletica-1329	96	6	62	62	NUM
ecletica-1329	96	7	eclética	eclética	PROPN
ecletica-1329	96	8	química	química	PROPN
ecletica-1329	96	9	,	,	PUNCT
ecletica-1329	96	10	vol	vol	NOUN
ecletica-1329	96	11	.	.	PROPN
ecletica-1329	96	12	48	48	NUM
ecletica-1329	96	13	,	,	PUNCT
ecletica-1329	96	14	n.	n.	NOUN
ecletica-1329	96	15	1	1	NUM
ecletica-1329	96	16	,	,	PUNCT
ecletica-1329	96	17	2023	2023	NUM
ecletica-1329	96	18	,	,	PUNCT
ecletica-1329	96	19	55	55	NUM
ecletica-1329	96	20	-	-	SYM
ecletica-1329	96	21	71	71	NUM
ecletica-1329	96	22	issn	issn	NOUN
ecletica-1329	96	23	:	:	PUNCT
ecletica-1329	96	24	1678	1678	NUM
ecletica-1329	96	25	-	-	SYM
ecletica-1329	96	26	4618	4618	NUM
ecletica-1329	96	27	doi	doi	NOUN
ecletica-1329	96	28	:	:	PUNCT
ecletica-1329	96	29	10.26850/1678	10.26850/1678	NUM
ecletica-1329	96	30	-	-	PUNCT
ecletica-1329	96	31	4618eqj.v48.1.2023.p55	4618eqj.v48.1.2023.p55	NUM
ecletica-1329	96	32	-	-	PUNCT
ecletica-1329	96	33	71	71	NUM
ecletica-1329	96	34	the	the	DET
ecletica-1329	96	35	negative	negative	ADJ
ecletica-1329	96	36	coefficients	coefficient	NOUN
ecletica-1329	96	37	of	of	ADP
ecletica-1329	96	38	the	the	DET
ecletica-1329	96	39	log	log	NOUN
ecletica-1329	96	40	p	p	NOUN
ecletica-1329	96	41	and	and	CCONJ
ecletica-1329	96	42	hba	hba	PROPN
ecletica-1329	96	43	descriptors	descriptor	NOUN
ecletica-1329	96	44	clearly	clearly	ADV
ecletica-1329	96	45	suggested	suggest	VERB
ecletica-1329	96	46	that	that	SCONJ
ecletica-1329	96	47	they	they	PRON
ecletica-1329	96	48	have	have	VERB
ecletica-1329	96	49	a	a	DET
ecletica-1329	96	50	negative	negative	ADJ
ecletica-1329	96	51	contribution	contribution	NOUN
ecletica-1329	96	52	to	to	ADP
ecletica-1329	96	53	the	the	DET
ecletica-1329	96	54	compounds	compound	NOUN
ecletica-1329	96	55	inhibitory	inhibitory	ADJ
ecletica-1329	96	56	actions	action	NOUN
ecletica-1329	96	57	.	.	PUNCT
ecletica-1329	97	1	this	this	PRON
ecletica-1329	97	2	suggests	suggest	VERB
ecletica-1329	97	3	that	that	SCONJ
ecletica-1329	97	4	reduction	reduction	NOUN
ecletica-1329	97	5	in	in	ADP
ecletica-1329	97	6	the	the	DET
ecletica-1329	97	7	amount	amount	NOUN
ecletica-1329	97	8	of	of	ADP
ecletica-1329	97	9	these	these	DET
ecletica-1329	97	10	independent	independent	ADJ
ecletica-1329	97	11	descriptors	descriptor	NOUN
ecletica-1329	97	12	improves	improve	VERB
ecletica-1329	97	13	the	the	DET
ecletica-1329	97	14	inhibition	inhibition	NOUN
ecletica-1329	97	15	concentration	concentration	NOUN
ecletica-1329	97	16	of	of	ADP
ecletica-1329	97	17	the	the	DET
ecletica-1329	97	18	studied	study	VERB
ecletica-1329	97	19	compounds	compound	NOUN
ecletica-1329	97	20	,	,	PUNCT
ecletica-1329	97	21	and	and	CCONJ
ecletica-1329	97	22	vice	vice	ADV
ecletica-1329	97	23	versa	versa	ADV
ecletica-1329	97	24	.	.	PUNCT
ecletica-1329	98	1	the	the	DET
ecletica-1329	98	2	positive	positive	ADJ
ecletica-1329	98	3	coefficients	coefficient	NOUN
ecletica-1329	98	4	of	of	ADP
ecletica-1329	98	5	dipole	dipole	NOUN
ecletica-1329	98	6	moment	moment	NOUN
ecletica-1329	98	7	and	and	CCONJ
ecletica-1329	98	8	molecular	molecular	ADJ
ecletica-1329	98	9	weight	weight	NOUN
ecletica-1329	98	10	in	in	ADP
ecletica-1329	98	11	the	the	DET
ecletica-1329	98	12	model	model	NOUN
ecletica-1329	98	13	,	,	PUNCT
ecletica-1329	98	14	on	on	ADP
ecletica-1329	98	15	the	the	DET
ecletica-1329	98	16	other	other	ADJ
ecletica-1329	98	17	hand	hand	NOUN
ecletica-1329	98	18	,	,	PUNCT
ecletica-1329	98	19	indicated	indicate	VERB
ecletica-1329	98	20	that	that	SCONJ
ecletica-1329	98	21	these	these	DET
ecletica-1329	98	22	independent	independent	ADJ
ecletica-1329	98	23	descriptors	descriptor	NOUN
ecletica-1329	98	24	contributed	contribute	VERB
ecletica-1329	98	25	positively	positively	ADV
ecletica-1329	98	26	to	to	ADP
ecletica-1329	98	27	the	the	DET
ecletica-1329	98	28	inhibitory	inhibitory	ADJ
ecletica-1329	98	29	effects	effect	NOUN
ecletica-1329	98	30	of	of	ADP
ecletica-1329	98	31	the	the	DET
ecletica-1329	98	32	ligands	ligand	NOUN
ecletica-1329	98	33	under	under	ADP
ecletica-1329	98	34	study	study	NOUN
ecletica-1329	98	35	.	.	PUNCT
ecletica-1329	99	1	it	it	PRON
ecletica-1329	99	2	suggests	suggest	VERB
ecletica-1329	99	3	that	that	SCONJ
ecletica-1329	99	4	by	by	ADP
ecletica-1329	99	5	increasing	increase	VERB
ecletica-1329	99	6	the	the	DET
ecletica-1329	99	7	amount	amount	NOUN
ecletica-1329	99	8	of	of	ADP
ecletica-1329	99	9	these	these	DET
ecletica-1329	99	10	descriptors	descriptor	NOUN
ecletica-1329	99	11	in	in	ADP
ecletica-1329	99	12	the	the	DET
ecletica-1329	99	13	structures	structure	NOUN
ecletica-1329	99	14	with	with	ADP
ecletica-1329	99	15	potential	potential	ADJ
ecletica-1329	99	16	anti	anti	ADJ
ecletica-1329	99	17	-	-	ADJ
ecletica-1329	99	18	egfr	egfr	ADJ
ecletica-1329	99	19	therapeutic	therapeutic	ADJ
ecletica-1329	99	20	agents	agent	NOUN
ecletica-1329	99	21	,	,	PUNCT
ecletica-1329	99	22	the	the	DET
ecletica-1329	99	23	inhibition	inhibition	NOUN
ecletica-1329	99	24	concentration	concentration	NOUN
ecletica-1329	99	25	these	these	DET
ecletica-1329	99	26	drug	drug	NOUN
ecletica-1329	99	27	-	-	PUNCT
ecletica-1329	99	28	like	like	ADJ
ecletica-1329	99	29	compounds	compound	NOUN
ecletica-1329	99	30	increases	increase	NOUN
ecletica-1329	99	31	and	and	CCONJ
ecletica-1329	99	32	vice	vice	NOUN
ecletica-1329	99	33	versa	versa	ADV
ecletica-1329	99	34	(	(	PUNCT
ecletica-1329	99	35	ibrahim	ibrahim	NOUN
ecletica-1329	99	36	et	et	PROPN
ecletica-1329	99	37	al	al	PROPN
ecletica-1329	99	38	.	.	PROPN
ecletica-1329	99	39	,	,	PUNCT
ecletica-1329	99	40	2020	2020	NUM
ecletica-1329	99	41	;	;	PUNCT
ecletica-1329	99	42	oke	oke	VERB
ecletica-1329	99	43	et	et	PROPN
ecletica-1329	99	44	al	al	PROPN
ecletica-1329	99	45	.	.	PROPN
ecletica-1329	99	46	,	,	PUNCT
ecletica-1329	99	47	2022	2022	NUM
ecletica-1329	99	48	)	)	PUNCT
ecletica-1329	99	49	.	.	PUNCT
ecletica-1329	100	1	also	also	ADV
ecletica-1329	100	2	,	,	PUNCT
ecletica-1329	100	3	as	as	SCONJ
ecletica-1329	100	4	reported	report	VERB
ecletica-1329	100	5	by	by	ADP
ecletica-1329	100	6	oyebamiji	oyebamiji	NOUN
ecletica-1329	100	7	et	et	PROPN
ecletica-1329	100	8	al	al	PROPN
ecletica-1329	100	9	.	.	PROPN
ecletica-1329	101	1	(	(	PUNCT
ecletica-1329	101	2	2021	2021	NUM
ecletica-1329	101	3	)	)	PUNCT
ecletica-1329	101	4	,	,	PUNCT
ecletica-1329	101	5	inhibition	inhibition	VERB
ecletica-1329	101	6	concentration	concentration	NOUN
ecletica-1329	101	7	of	of	ADP
ecletica-1329	101	8	any	any	DET
ecletica-1329	101	9	developed	develop	VERB
ecletica-1329	101	10	qsar	qsar	NOUN
ecletica-1329	101	11	model	model	NOUN
ecletica-1329	101	12	is	be	AUX
ecletica-1329	101	13	not	not	PART
ecletica-1329	101	14	enough	enough	ADJ
ecletica-1329	101	15	to	to	PART
ecletica-1329	101	16	judge	judge	VERB
ecletica-1329	101	17	the	the	DET
ecletica-1329	101	18	potency	potency	NOUN
ecletica-1329	101	19	of	of	ADP
ecletica-1329	101	20	such	such	ADJ
ecletica-1329	101	21	model	model	NOUN
ecletica-1329	101	22	and	and	CCONJ
ecletica-1329	101	23	this	this	PRON
ecletica-1329	101	24	therefore	therefore	ADV
ecletica-1329	101	25	called	call	VERB
ecletica-1329	101	26	for	for	ADP
ecletica-1329	101	27	validation	validation	NOUN
ecletica-1329	101	28	of	of	ADP
ecletica-1329	101	29	the	the	DET
ecletica-1329	101	30	developed	develop	VERB
ecletica-1329	101	31	qsar	qsar	NOUN
ecletica-1329	101	32	model	model	NOUN
ecletica-1329	101	33	.	.	PUNCT
ecletica-1329	102	1	the	the	DET
ecletica-1329	102	2	calculated	calculate	VERB
ecletica-1329	102	3	factors	factor	NOUN
ecletica-1329	102	4	considered	consider	VERB
ecletica-1329	102	5	for	for	ADP
ecletica-1329	102	6	validation	validation	NOUN
ecletica-1329	102	7	were	be	AUX
ecletica-1329	102	8	cross	cross	NOUN
ecletica-1329	102	9	validation	validation	NOUN
ecletica-1329	102	10	(	(	PUNCT
ecletica-1329	102	11	cv.r2	cv.r2	NOUN
ecletica-1329	102	12	)	)	PUNCT
ecletica-1329	102	13	and	and	CCONJ
ecletica-1329	102	14	adjusted	adjust	VERB
ecletica-1329	102	15	squared	square	VERB
ecletica-1329	102	16	correlation	correlation	NOUN
ecletica-1329	102	17	coefficient	coefficient	NOUN
ecletica-1329	102	18	(	(	PUNCT
ecletica-1329	102	19	adj.r2	adj.r2	NOUN
ecletica-1329	102	20	)	)	PUNCT
ecletica-1329	102	21	.	.	PUNCT
ecletica-1329	103	1	table	table	NOUN
ecletica-1329	104	1	3	3	NUM
ecletica-1329	104	2	.	.	PUNCT
ecletica-1329	105	1	statistical	statistical	ADJ
ecletica-1329	105	2	parameters	parameter	NOUN
ecletica-1329	105	3	and	and	CCONJ
ecletica-1329	105	4	limit	limit	NOUN
ecletica-1329	105	5	needed	need	VERB
ecletica-1329	105	6	for	for	ADP
ecletica-1329	105	7	the	the	DET
ecletica-1329	105	8	qsar	qsar	PROPN
ecletica-1329	105	9	model	model	NOUN
ecletica-1329	105	10	assessment	assessment	NOUN
ecletica-1329	105	11	.	.	PUNCT
ecletica-1329	106	1	statistical	statistical	ADJ
ecletica-1329	106	2	parameters	parameter	NOUN
ecletica-1329	106	3	details	detail	NOUN
ecletica-1329	106	4	accepted	accept	VERB
ecletica-1329	106	5	value	value	NOUN
ecletica-1329	106	6	selected	select	VERB
ecletica-1329	106	7	model	model	NOUN
ecletica-1329	106	8	r2	r2	PROPN
ecletica-1329	106	9	correlation	correlation	NOUN
ecletica-1329	106	10	coefficient	coefficient	NOUN
ecletica-1329	106	11	≥	≥	NUM
ecletica-1329	106	12	0.6	0.6	NUM
ecletica-1329	106	13	0.9525	0.9525	NUM
ecletica-1329	106	14	r2	r2	PROPN
ecletica-1329	106	15	adj	adj	NOUN
ecletica-1329	106	16	squared	square	VERB
ecletica-1329	106	17	correlation	correlation	NOUN
ecletica-1329	106	18	coefficient	coefficient	NOUN
ecletica-1329	106	19	≥	≥	NUM
ecletica-1329	106	20	0.6	0.6	NUM
ecletica-1329	106	21	0.9314	0.9314	NUM
ecletica-1329	106	22	cv.r	cv.r	NOUN
ecletica-1329	106	23	cross	cross	ADJ
ecletica-1329	106	24	-	-	ADJ
ecletica-1329	106	25	validation	validation	ADJ
ecletica-1329	106	26	coefficient	coefficient	NOUN
ecletica-1329	106	27	≥	≥	NUM
ecletica-1329	106	28	0.5	0.5	NUM
ecletica-1329	106	29	0.9719	0.9719	NUM
ecletica-1329	106	30	cv.r	cv.r	NOUN
ecletica-1329	106	31	–	–	PUNCT
ecletica-1329	106	32	r2	r2	NOUN
ecletica-1329	106	33	adj	adj	X
ecletica-1329	106	34	difference	difference	NOUN
ecletica-1329	106	35	between	between	ADP
ecletica-1329	106	36	cv.r	cv.r	NOUN
ecletica-1329	106	37	and	and	CCONJ
ecletica-1329	106	38	r2	r2	PROPN
ecletica-1329	106	39	≥	≥	NUM
ecletica-1329	106	40	0.3	0.3	NUM
ecletica-1329	106	41	0.0405	0.0405	NUM
ecletica-1329	106	42	the	the	DET
ecletica-1329	106	43	validation	validation	NOUN
ecletica-1329	106	44	factors	factor	NOUN
ecletica-1329	106	45	revealed	reveal	VERB
ecletica-1329	106	46	in	in	ADP
ecletica-1329	106	47	this	this	DET
ecletica-1329	106	48	study	study	NOUN
ecletica-1329	106	49	matched	match	VERB
ecletica-1329	106	50	the	the	DET
ecletica-1329	106	51	validation	validation	NOUN
ecletica-1329	106	52	parameters	parameter	NOUN
ecletica-1329	106	53	in	in	ADP
ecletica-1329	106	54	table	table	NOUN
ecletica-1329	106	55	3	3	NUM
ecletica-1329	106	56	,	,	PUNCT
ecletica-1329	106	57	indicating	indicate	VERB
ecletica-1329	106	58	that	that	SCONJ
ecletica-1329	106	59	the	the	DET
ecletica-1329	106	60	model	model	NOUN
ecletica-1329	106	61	created	create	VERB
ecletica-1329	106	62	is	be	AUX
ecletica-1329	106	63	both	both	CCONJ
ecletica-1329	106	64	predictive	predictive	ADJ
ecletica-1329	106	65	and	and	CCONJ
ecletica-1329	106	66	resilient	resilient	ADJ
ecletica-1329	106	67	.	.	PUNCT
ecletica-1329	107	1	for	for	ADP
ecletica-1329	107	2	the	the	DET
ecletica-1329	107	3	compounds	compound	NOUN
ecletica-1329	107	4	under	under	ADP
ecletica-1329	107	5	examination	examination	NOUN
ecletica-1329	107	6	,	,	PUNCT
ecletica-1329	107	7	table	table	NOUN
ecletica-1329	107	8	4	4	NUM
ecletica-1329	107	9	displays	display	VERB
ecletica-1329	107	10	the	the	DET
ecletica-1329	107	11	experimental	experimental	ADJ
ecletica-1329	107	12	ic50	ic50	PROPN
ecletica-1329	107	13	,	,	PUNCT
ecletica-1329	107	14	predicted	predict	VERB
ecletica-1329	107	15	ic50	ic50	PROPN
ecletica-1329	107	16	,	,	PUNCT
ecletica-1329	107	17	and	and	CCONJ
ecletica-1329	107	18	residual	residual	ADJ
ecletica-1329	107	19	values	value	NOUN
ecletica-1329	107	20	.	.	PUNCT
ecletica-1329	108	1	the	the	DET
ecletica-1329	108	2	minimal	minimal	ADJ
ecletica-1329	108	3	residual	residual	ADJ
ecletica-1329	108	4	values	value	NOUN
ecletica-1329	108	5	observed	observe	VERB
ecletica-1329	108	6	between	between	ADP
ecletica-1329	108	7	the	the	DET
ecletica-1329	108	8	experimental	experimental	ADJ
ecletica-1329	108	9	and	and	CCONJ
ecletica-1329	108	10	predicted	predict	VERB
ecletica-1329	108	11	ic50	ic50	PROPN
ecletica-1329	108	12	in	in	ADP
ecletica-1329	108	13	the	the	DET
ecletica-1329	108	14	table	table	NOUN
ecletica-1329	108	15	validated	validate	VERB
ecletica-1329	108	16	the	the	DET
ecletica-1329	108	17	model	model	NOUN
ecletica-1329	108	18	’s	’s	PART
ecletica-1329	108	19	high	high	ADJ
ecletica-1329	108	20	anticipated	anticipate	VERB
ecletica-1329	108	21	power	power	NOUN
ecletica-1329	108	22	(	(	PUNCT
ecletica-1329	108	23	meaning	mean	VERB
ecletica-1329	108	24	that	that	SCONJ
ecletica-1329	108	25	the	the	DET
ecletica-1329	108	26	reported	report	VERB
ecletica-1329	108	27	model	model	NOUN
ecletica-1329	108	28	was	be	AUX
ecletica-1329	108	29	reliable	reliable	ADJ
ecletica-1329	108	30	with	with	ADP
ecletica-1329	108	31	high	high	ADJ
ecletica-1329	108	32	predicted	predict	VERB
ecletica-1329	108	33	power	power	NOUN
ecletica-1329	108	34	)	)	PUNCT
ecletica-1329	108	35	.	.	PUNCT
ecletica-1329	109	1	figure	figure	NOUN
ecletica-1329	109	2	1	1	NUM
ecletica-1329	109	3	also	also	ADV
ecletica-1329	109	4	shows	show	VERB
ecletica-1329	109	5	a	a	DET
ecletica-1329	109	6	plot	plot	NOUN
ecletica-1329	109	7	of	of	ADP
ecletica-1329	109	8	the	the	DET
ecletica-1329	109	9	predicted	predict	VERB
ecletica-1329	109	10	ic50	ic50	PROPN
ecletica-1329	109	11	versus	versus	ADP
ecletica-1329	109	12	experimental	experimental	ADJ
ecletica-1329	109	13	ic50	ic50	PROPN
ecletica-1329	109	14	for	for	ADP
ecletica-1329	109	15	the	the	DET
ecletica-1329	109	16	compounds	compound	NOUN
ecletica-1329	109	17	,	,	PUNCT
ecletica-1329	109	18	and	and	CCONJ
ecletica-1329	109	19	the	the	DET
ecletica-1329	109	20	distribution	distribution	NOUN
ecletica-1329	109	21	of	of	ADP
ecletica-1329	109	22	the	the	DET
ecletica-1329	109	23	predicted	predict	VERB
ecletica-1329	109	24	ic50	ic50	PROPN
ecletica-1329	109	25	and	and	CCONJ
ecletica-1329	109	26	experimental	experimental	ADJ
ecletica-1329	109	27	ic50	ic50	PROPN
ecletica-1329	109	28	of	of	ADP
ecletica-1329	109	29	the	the	DET
ecletica-1329	109	30	compounds	compound	NOUN
ecletica-1329	109	31	along	along	ADP
ecletica-1329	109	32	the	the	DET
ecletica-1329	109	33	line	line	NOUN
ecletica-1329	109	34	reaffirmed	reaffirm	VERB
ecletica-1329	109	35	the	the	DET
ecletica-1329	109	36	model	model	NOUN
ecletica-1329	109	37	’s	’s	PART
ecletica-1329	109	38	dependability	dependability	NOUN
ecletica-1329	109	39	.	.	PUNCT
ecletica-1329	110	1	the	the	DET
ecletica-1329	110	2	r2	r2	PROPN
ecletica-1329	110	3	values	value	NOUN
ecletica-1329	110	4	of	of	ADP
ecletica-1329	110	5	the	the	DET
ecletica-1329	110	6	internal	internal	ADJ
ecletica-1329	110	7	validation	validation	NOUN
ecletica-1329	110	8	(	(	PUNCT
ecletica-1329	110	9	0.9525	0.9525	NUM
ecletica-1329	110	10	)	)	PUNCT
ecletica-1329	110	11	and	and	CCONJ
ecletica-1329	110	12	the	the	DET
ecletica-1329	110	13	plot	plot	NOUN
ecletica-1329	110	14	(	(	PUNCT
ecletica-1329	110	15	0.9944	0.9944	NUM
ecletica-1329	110	16	)	)	PUNCT
ecletica-1329	110	17	agreed	agree	VERB
ecletica-1329	110	18	with	with	ADP
ecletica-1329	110	19	one	one	NUM
ecletica-1329	110	20	another	another	DET
ecletica-1329	110	21	,	,	PUNCT
ecletica-1329	110	22	confirming	confirm	VERB
ecletica-1329	110	23	the	the	DET
ecletica-1329	110	24	reported	reported	ADJ
ecletica-1329	110	25	model	model	NOUN
ecletica-1329	110	26	’s	’s	PART
ecletica-1329	110	27	stability	stability	NOUN
ecletica-1329	110	28	and	and	CCONJ
ecletica-1329	110	29	reliability	reliability	NOUN
ecletica-1329	110	30	(	(	PUNCT
ecletica-1329	110	31	grisoni	grisoni	VERB
ecletica-1329	110	32	et	et	PROPN
ecletica-1329	110	33	al	al	PROPN
ecletica-1329	110	34	.	.	PROPN
ecletica-1329	110	35	,	,	PUNCT
ecletica-1329	110	36	2018	2018	NUM
ecletica-1329	110	37	)	)	PUNCT
ecletica-1329	110	38	.	.	PUNCT
ecletica-1329	111	1	furthermore	furthermore	ADV
ecletica-1329	111	2	,	,	PUNCT
ecletica-1329	111	3	fig	fig	NOUN
ecletica-1329	111	4	.	.	PUNCT
ecletica-1329	111	5	2	2	NUM
ecletica-1329	111	6	shows	show	VERB
ecletica-1329	111	7	a	a	DET
ecletica-1329	111	8	scatter	scatter	NOUN
ecletica-1329	111	9	plot	plot	NOUN
ecletica-1329	111	10	of	of	ADP
ecletica-1329	111	11	residuals	residual	NOUN
ecletica-1329	111	12	against	against	ADP
ecletica-1329	111	13	the	the	DET
ecletica-1329	111	14	experimental	experimental	ADJ
ecletica-1329	111	15	ic50	ic50	PROPN
ecletica-1329	111	16	which	which	PRON
ecletica-1329	111	17	the	the	DET
ecletica-1329	111	18	remarkable	remarkable	ADJ
ecletica-1329	111	19	appearance	appearance	NOUN
ecletica-1329	111	20	of	of	ADP
ecletica-1329	111	21	both	both	DET
ecletica-1329	111	22	sets	set	NOUN
ecletica-1329	111	23	of	of	ADP
ecletica-1329	111	24	residuals	residual	NOUN
ecletica-1329	111	25	on	on	ADP
ecletica-1329	111	26	the	the	DET
ecletica-1329	111	27	plot	plot	NOUN
ecletica-1329	111	28	's	's	PART
ecletica-1329	111	29	top	top	ADJ
ecletica-1329	111	30	and	and	CCONJ
ecletica-1329	111	31	lower	low	ADJ
ecletica-1329	111	32	sides	side	NOUN
ecletica-1329	111	33	confirms	confirm	VERB
ecletica-1329	111	34	that	that	SCONJ
ecletica-1329	111	35	the	the	DET
ecletica-1329	111	36	reported	report	VERB
ecletica-1329	111	37	model	model	NOUN
ecletica-1329	111	38	was	be	AUX
ecletica-1329	111	39	free	free	ADJ
ecletica-1329	111	40	of	of	ADP
ecletica-1329	111	41	methodological	methodological	ADJ
ecletica-1329	111	42	mistake	mistake	NOUN
ecletica-1329	111	43	(	(	PUNCT
ecletica-1329	111	44	systematic	systematic	ADJ
ecletica-1329	111	45	deviations	deviation	NOUN
ecletica-1329	111	46	)	)	PUNCT
ecletica-1329	111	47	.	.	PUNCT
ecletica-1329	112	1	table	table	NOUN
ecletica-1329	112	2	4	4	NUM
ecletica-1329	112	3	.	.	PUNCT
ecletica-1329	113	1	the	the	DET
ecletica-1329	113	2	experimental	experimental	ADJ
ecletica-1329	113	3	ic50	ic50	PROPN
ecletica-1329	113	4	,	,	PUNCT
ecletica-1329	113	5	predicted	predict	VERB
ecletica-1329	113	6	ic50	ic50	PROPN
ecletica-1329	113	7	and	and	CCONJ
ecletica-1329	113	8	the	the	DET
ecletica-1329	113	9	residual	residual	ADJ
ecletica-1329	113	10	values	value	NOUN
ecletica-1329	113	11	for	for	ADP
ecletica-1329	113	12	the	the	DET
ecletica-1329	113	13	studied	study	VERB
ecletica-1329	113	14	compounds	compound	NOUN
ecletica-1329	113	15	.	.	PUNCT
ecletica-1329	114	1	experimental	experimental	ADJ
ecletica-1329	114	2	ic50	ic50	PROPN
ecletica-1329	114	3	predicted	predict	VERB
ecletica-1329	114	4	ic50	ic50	PROPN
ecletica-1329	114	5	residual	residual	ADJ
ecletica-1329	114	6	c1	c1	NOUN
ecletica-1329	114	7	85.5	85.5	NUM
ecletica-1329	114	8	80.66	80.66	NUM
ecletica-1329	114	9	4.84	4.84	NUM
ecletica-1329	114	10	c2	c2	PROPN
ecletica-1329	114	11	58.6	58.6	NUM
ecletica-1329	114	12	55.85	55.85	NUM
ecletica-1329	114	13	2.75	2.75	NUM
ecletica-1329	114	14	c3	c3	NOUN
ecletica-1329	114	15	17.9	17.9	NUM
ecletica-1329	114	16	19.05	19.05	NUM
ecletica-1329	114	17	–	–	PUNCT
ecletica-1329	114	18	1.15	1.15	NUM
ecletica-1329	114	19	c4	c4	NOUN
ecletica-1329	114	20	35.14	35.14	NUM
ecletica-1329	114	21	29.45	29.45	NUM
ecletica-1329	114	22	5.69	5.69	NUM
ecletica-1329	114	23	c5	c5	PROPN
ecletica-1329	114	24	15.4	15.4	NUM
ecletica-1329	114	25	14.77	14.77	NUM
ecletica-1329	114	26	0.63	0.63	NUM
ecletica-1329	114	27	c6	c6	PROPN
ecletica-1329	114	28	1.37	1.37	NUM
ecletica-1329	114	29	2.68	2.68	NUM
ecletica-1329	114	30	–	–	PUNCT
ecletica-1329	114	31	1.31	1.31	NUM
ecletica-1329	114	32	c7	c7	PROPN
ecletica-1329	114	33	1.2	1.2	NUM
ecletica-1329	114	34	1.75	1.75	NUM
ecletica-1329	114	35	0.55	0.55	NUM
ecletica-1329	114	36	c8	c8	NOUN
ecletica-1329	114	37	1.1	1.1	NUM
ecletica-1329	114	38	1.16	1.16	NUM
ecletica-1329	114	39	–	–	PUNCT
ecletica-1329	114	40	0.06	0.06	NUM
ecletica-1329	114	41	c9	c9	NOUN
ecletica-1329	114	42	39.6	39.6	NUM
ecletica-1329	114	43	42.03	42.03	NUM
ecletica-1329	114	44	–	–	PUNCT
ecletica-1329	114	45	2.43	2.43	NUM
ecletica-1329	114	46	c10	c10	VERB
ecletica-1329	114	47	4.2	4.2	NUM
ecletica-1329	114	48	4.44	4.44	NUM
ecletica-1329	114	49	–	–	PUNCT
ecletica-1329	114	50	0.24	0.24	NUM
ecletica-1329	114	51	c11	c11	NOUN
ecletica-1329	114	52	3.1	3.1	NUM
ecletica-1329	114	53	1.04	1.04	NUM
ecletica-1329	114	54	2.06	2.06	NUM
ecletica-1329	114	55	c12	c12	NOUN
ecletica-1329	114	56	2.0	2.0	NUM
ecletica-1329	114	57	1.62	1.62	NUM
ecletica-1329	114	58	0.38	0.38	NUM
ecletica-1329	114	59	c13	c13	PROPN
ecletica-1329	114	60	1.06	1.06	NUM
ecletica-1329	114	61	1.01	1.01	NUM
ecletica-1329	114	62	0.05	0.05	NUM
ecletica-1329	114	63	c14	c14	NOUN
ecletica-1329	114	64	0.69	0.69	NUM
ecletica-1329	114	65	1.79	1.79	NUM
ecletica-1329	114	66	–	–	PUNCT
ecletica-1329	114	67	1.10	1.10	NUM
ecletica-1329	114	68	table	table	NOUN
ecletica-1329	114	69	6	6	NUM
ecletica-1329	114	70	shows	show	VERB
ecletica-1329	114	71	the	the	DET
ecletica-1329	114	72	correlation	correlation	NOUN
ecletica-1329	114	73	statistical	statistical	ADJ
ecletica-1329	114	74	analysis	analysis	NOUN
ecletica-1329	114	75	of	of	ADP
ecletica-1329	114	76	the	the	DET
ecletica-1329	114	77	independent	independent	ADJ
ecletica-1329	114	78	descriptors	descriptor	NOUN
ecletica-1329	114	79	in	in	ADP
ecletica-1329	114	80	the	the	DET
ecletica-1329	114	81	presented	present	VERB
ecletica-1329	114	82	model	model	NOUN
ecletica-1329	114	83	,	,	PUNCT
ecletica-1329	114	84	which	which	PRON
ecletica-1329	114	85	revealed	reveal	VERB
ecletica-1329	114	86	that	that	SCONJ
ecletica-1329	114	87	there	there	PRON
ecletica-1329	114	88	is	be	VERB
ecletica-1329	114	89	no	no	DET
ecletica-1329	114	90	relationship	relationship	NOUN
ecletica-1329	114	91	between	between	ADP
ecletica-1329	114	92	the	the	DET
ecletica-1329	114	93	descriptors	descriptor	NOUN
ecletica-1329	114	94	in	in	ADP
ecletica-1329	114	95	the	the	DET
ecletica-1329	114	96	model	model	NOUN
ecletica-1329	114	97	.	.	PUNCT
ecletica-1329	115	1	this	this	PRON
ecletica-1329	115	2	demonstrated	demonstrate	VERB
ecletica-1329	115	3	the	the	DET
ecletica-1329	115	4	good	good	ADJ
ecletica-1329	115	5	performance	performance	NOUN
ecletica-1329	115	6	of	of	ADP
ecletica-1329	115	7	the	the	DET
ecletica-1329	115	8	descriptors	descriptor	NOUN
ecletica-1329	115	9	utilized	utilize	VERB
ecletica-1329	115	10	in	in	ADP
ecletica-1329	115	11	creating	create	VERB
ecletica-1329	115	12	the	the	DET
ecletica-1329	115	13	reported	reported	ADJ
ecletica-1329	115	14	model	model	NOUN
ecletica-1329	115	15	.	.	PUNCT
ecletica-1329	116	1	the	the	DET
ecletica-1329	116	2	variation	variation	NOUN
ecletica-1329	116	3	inflation	inflation	NOUN
ecletica-1329	116	4	factor	factor	NOUN
ecletica-1329	116	5	(	(	PUNCT
ecletica-1329	116	6	vif	vif	PROPN
ecletica-1329	116	7	)	)	PUNCT
ecletica-1329	116	8	data	datum	NOUN
ecletica-1329	116	9	were	be	AUX
ecletica-1329	116	10	also	also	ADV
ecletica-1329	116	11	examined	examine	VERB
ecletica-1329	116	12	to	to	PART
ecletica-1329	116	13	see	see	VERB
ecletica-1329	116	14	if	if	SCONJ
ecletica-1329	116	15	the	the	DET
ecletica-1329	116	16	descriptors	descriptor	NOUN
ecletica-1329	116	17	employed	employ	VERB
ecletica-1329	116	18	in	in	ADP
ecletica-1329	116	19	the	the	DET
ecletica-1329	116	20	model	model	NOUN
ecletica-1329	116	21	had	have	VERB
ecletica-1329	116	22	any	any	DET
ecletica-1329	116	23	multicollinearity	multicollinearity	NOUN
ecletica-1329	116	24	issues	issue	NOUN
ecletica-1329	116	25	.	.	PUNCT
ecletica-1329	117	1	in	in	ADP
ecletica-1329	117	2	general	general	ADJ
ecletica-1329	117	3	,	,	PUNCT
ecletica-1329	117	4	a	a	DET
ecletica-1329	117	5	vif	vif	NOUN
ecletica-1329	117	6	value	value	NOUN
ecletica-1329	117	7	of	of	ADP
ecletica-1329	117	8	1	1	NUM
ecletica-1329	117	9	or	or	CCONJ
ecletica-1329	117	10	a	a	DET
ecletica-1329	117	11	value	value	NOUN
ecletica-1329	117	12	between	between	ADP
ecletica-1329	117	13	1	1	NUM
ecletica-1329	117	14	and	and	CCONJ
ecletica-1329	117	15	5	5	NUM
ecletica-1329	117	16	indicates	indicate	VERB
ecletica-1329	117	17	that	that	SCONJ
ecletica-1329	117	18	there	there	PRON
ecletica-1329	117	19	is	be	VERB
ecletica-1329	117	20	no	no	DET
ecletica-1329	117	21	intercorrelation	intercorrelation	NOUN
ecletica-1329	117	22	between	between	ADP
ecletica-1329	117	23	the	the	DET
ecletica-1329	117	24	descriptors	descriptor	NOUN
ecletica-1329	117	25	.	.	PUNCT
ecletica-1329	118	1	nevertheless	nevertheless	ADV
ecletica-1329	118	2	,	,	PUNCT
ecletica-1329	118	3	if	if	SCONJ
ecletica-1329	118	4	the	the	DET
ecletica-1329	118	5	vif	vif	NOUN
ecletica-1329	118	6	value	value	NOUN
ecletica-1329	118	7	is	be	AUX
ecletica-1329	118	8	larger	large	ADJ
ecletica-1329	118	9	than	than	ADP
ecletica-1329	118	10	10	10	NUM
ecletica-1329	118	11	,	,	PUNCT
ecletica-1329	118	12	the	the	DET
ecletica-1329	118	13	produced	produce	VERB
ecletica-1329	118	14	model	model	NOUN
ecletica-1329	118	15	is	be	AUX
ecletica-1329	118	16	https://revista.iq.unesp.br/index.php/ecletica	https://revista.iq.unesp.br/index.php/ecletica	PROPN
ecletica-1329	118	17	https://doi.org/10.26850/1678-4618eqj.v48.1.2023.p55-71	https://doi.org/10.26850/1678-4618eqj.v48.1.2023.p55-71	PROPN
ecletica-1329	118	18	original	original	ADJ
ecletica-1329	118	19	article	article	NOUN
ecletica-1329	118	20	revista.iq.unesp.br	revista.iq.unesp.br	PROPN
ecletica-1329	118	21	63	63	NUM
ecletica-1329	118	22	eclética	eclética	PROPN
ecletica-1329	118	23	química	química	PROPN
ecletica-1329	118	24	,	,	PUNCT
ecletica-1329	118	25	vol	vol	NOUN
ecletica-1329	118	26	.	.	PROPN
ecletica-1329	118	27	48	48	NUM
ecletica-1329	118	28	,	,	PUNCT
ecletica-1329	118	29	n.	n.	NOUN
ecletica-1329	118	30	1	1	NUM
ecletica-1329	118	31	,	,	PUNCT
ecletica-1329	118	32	2023	2023	NUM
ecletica-1329	118	33	,	,	PUNCT
ecletica-1329	118	34	55	55	NUM
ecletica-1329	118	35	-	-	SYM
ecletica-1329	118	36	71	71	NUM
ecletica-1329	118	37	issn	issn	NOUN
ecletica-1329	118	38	:	:	PUNCT
ecletica-1329	118	39	1678	1678	NUM
ecletica-1329	118	40	-	-	SYM
ecletica-1329	118	41	4618	4618	NUM
ecletica-1329	118	42	doi	doi	NOUN
ecletica-1329	118	43	:	:	PUNCT
ecletica-1329	118	44	10.26850/1678	10.26850/1678	NUM
ecletica-1329	118	45	-	-	PUNCT
ecletica-1329	118	46	4618eqj.v48.1.2023.p55	4618eqj.v48.1.2023.p55	NUM
ecletica-1329	118	47	-	-	PUNCT
ecletica-1329	118	48	71	71	NUM
ecletica-1329	118	49	unstable	unstable	ADJ
ecletica-1329	118	50	,	,	PUNCT
ecletica-1329	118	51	and	and	CCONJ
ecletica-1329	118	52	the	the	DET
ecletica-1329	118	53	model	model	NOUN
ecletica-1329	118	54	should	should	AUX
ecletica-1329	118	55	be	be	AUX
ecletica-1329	118	56	rechecked	rechecke	VERB
ecletica-1329	118	57	if	if	SCONJ
ecletica-1329	118	58	desired	desire	VERB
ecletica-1329	118	59	(	(	PUNCT
ecletica-1329	118	60	beheshti	beheshti	VERB
ecletica-1329	118	61	et	et	PROPN
ecletica-1329	118	62	al	al	PROPN
ecletica-1329	118	63	.	.	PROPN
ecletica-1329	118	64	,	,	PUNCT
ecletica-1329	118	65	2016	2016	NUM
ecletica-1329	118	66	)	)	PUNCT
ecletica-1329	118	67	.	.	PUNCT
ecletica-1329	119	1	table	table	NOUN
ecletica-1329	119	2	5	5	NUM
ecletica-1329	119	3	shows	show	VERB
ecletica-1329	119	4	that	that	SCONJ
ecletica-1329	119	5	the	the	DET
ecletica-1329	119	6	vif	vif	NOUN
ecletica-1329	119	7	values	value	NOUN
ecletica-1329	119	8	for	for	ADP
ecletica-1329	119	9	each	each	DET
ecletica-1329	119	10	descriptor	descriptor	NOUN
ecletica-1329	119	11	were	be	AUX
ecletica-1329	119	12	less	less	ADJ
ecletica-1329	119	13	than	than	ADP
ecletica-1329	119	14	5	5	NUM
ecletica-1329	119	15	,	,	PUNCT
ecletica-1329	119	16	indicating	indicate	VERB
ecletica-1329	119	17	that	that	SCONJ
ecletica-1329	119	18	the	the	DET
ecletica-1329	119	19	descriptors	descriptor	NOUN
ecletica-1329	119	20	were	be	AUX
ecletica-1329	119	21	highly	highly	ADV
ecletica-1329	119	22	orthogonal	orthogonal	ADJ
ecletica-1329	119	23	to	to	ADP
ecletica-1329	119	24	each	each	DET
ecletica-1329	119	25	other	other	ADJ
ecletica-1329	119	26	and	and	CCONJ
ecletica-1329	119	27	that	that	SCONJ
ecletica-1329	119	28	there	there	PRON
ecletica-1329	119	29	was	be	VERB
ecletica-1329	119	30	no	no	DET
ecletica-1329	119	31	intercorrelation	intercorrelation	NOUN
ecletica-1329	119	32	between	between	ADP
ecletica-1329	119	33	them	they	PRON
ecletica-1329	119	34	.	.	PUNCT
ecletica-1329	120	1	this	this	PRON
ecletica-1329	120	2	demonstrates	demonstrate	VERB
ecletica-1329	120	3	that	that	SCONJ
ecletica-1329	120	4	the	the	DET
ecletica-1329	120	5	descriptors	descriptor	NOUN
ecletica-1329	120	6	used	use	VERB
ecletica-1329	120	7	to	to	PART
ecletica-1329	120	8	construct	construct	VERB
ecletica-1329	120	9	the	the	DET
ecletica-1329	120	10	provided	provide	VERB
ecletica-1329	120	11	model	model	NOUN
ecletica-1329	120	12	do	do	AUX
ecletica-1329	120	13	not	not	PART
ecletica-1329	120	14	have	have	VERB
ecletica-1329	120	15	a	a	DET
ecletica-1329	120	16	multicollinearity	multicollinearity	NOUN
ecletica-1329	120	17	problem	problem	NOUN
ecletica-1329	120	18	.	.	PUNCT
ecletica-1329	121	1	a	a	DET
ecletica-1329	121	2	one	one	NUM
ecletica-1329	121	3	-	-	PUNCT
ecletica-1329	121	4	way	way	NOUN
ecletica-1329	121	5	analysis	analysis	NOUN
ecletica-1329	121	6	of	of	ADP
ecletica-1329	121	7	variance	variance	NOUN
ecletica-1329	121	8	was	be	AUX
ecletica-1329	121	9	used	use	VERB
ecletica-1329	121	10	to	to	PART
ecletica-1329	121	11	determine	determine	VERB
ecletica-1329	121	12	the	the	DET
ecletica-1329	121	13	association	association	NOUN
ecletica-1329	121	14	between	between	ADP
ecletica-1329	121	15	the	the	DET
ecletica-1329	121	16	descriptors	descriptor	NOUN
ecletica-1329	121	17	and	and	CCONJ
ecletica-1329	121	18	each	each	DET
ecletica-1329	121	19	compound	compound	NOUN
ecletica-1329	121	20	’s	’s	PART
ecletica-1329	121	21	biological	biological	ADJ
ecletica-1329	121	22	activity	activity	NOUN
ecletica-1329	121	23	(	(	PUNCT
ecletica-1329	121	24	anova	anova	PROPN
ecletica-1329	121	25	)	)	PUNCT
ecletica-1329	121	26	.	.	PUNCT
ecletica-1329	122	1	table	table	NOUN
ecletica-1329	122	2	5	5	NUM
ecletica-1329	122	3	shows	show	VERB
ecletica-1329	122	4	the	the	DET
ecletica-1329	122	5	probability	probability	NOUN
ecletica-1329	122	6	value	value	NOUN
ecletica-1329	122	7	of	of	ADP
ecletica-1329	122	8	each	each	DET
ecletica-1329	122	9	descriptor	descriptor	NOUN
ecletica-1329	122	10	at	at	ADP
ecletica-1329	122	11	the	the	DET
ecletica-1329	122	12	95	95	NUM
ecletica-1329	122	13	%	%	NOUN
ecletica-1329	122	14	confidence	confidence	NOUN
ecletica-1329	122	15	level	level	NOUN
ecletica-1329	122	16	(	(	PUNCT
ecletica-1329	122	17	p	p	X
ecletica-1329	122	18	=	=	NOUN
ecletica-1329	122	19	0.05	0.05	NUM
ecletica-1329	122	20	)	)	PUNCT
ecletica-1329	122	21	.	.	PUNCT
ecletica-1329	123	1	as	as	ADP
ecletica-1329	123	2	a	a	DET
ecletica-1329	123	3	result	result	NOUN
ecletica-1329	123	4	,	,	PUNCT
ecletica-1329	123	5	the	the	DET
ecletica-1329	123	6	alternative	alternative	ADJ
ecletica-1329	123	7	hypothesis	hypothesis	NOUN
ecletica-1329	123	8	stating	state	VERB
ecletica-1329	123	9	that	that	SCONJ
ecletica-1329	123	10	there	there	PRON
ecletica-1329	123	11	is	be	VERB
ecletica-1329	123	12	a	a	DET
ecletica-1329	123	13	direct	direct	ADJ
ecletica-1329	123	14	relationship	relationship	NOUN
ecletica-1329	123	15	between	between	ADP
ecletica-1329	123	16	the	the	DET
ecletica-1329	123	17	biological	biological	ADJ
ecletica-1329	123	18	activity	activity	NOUN
ecletica-1329	123	19	of	of	ADP
ecletica-1329	123	20	each	each	DET
ecletica-1329	123	21	compound	compound	NOUN
ecletica-1329	123	22	and	and	CCONJ
ecletica-1329	123	23	the	the	DET
ecletica-1329	123	24	descriptor	descriptor	NOUN
ecletica-1329	123	25	swaying	sway	VERB
ecletica-1329	123	26	the	the	DET
ecletica-1329	123	27	built	build	VERB
ecletica-1329	123	28	model	model	NOUN
ecletica-1329	123	29	is	be	AUX
ecletica-1329	123	30	accepted	accept	VERB
ecletica-1329	123	31	;	;	PUNCT
ecletica-1329	123	32	however	however	ADV
ecletica-1329	123	33	,	,	PUNCT
ecletica-1329	123	34	the	the	DET
ecletica-1329	123	35	null	null	ADJ
ecletica-1329	123	36	hypothesis	hypothesis	NOUN
ecletica-1329	123	37	stating	state	VERB
ecletica-1329	123	38	that	that	SCONJ
ecletica-1329	123	39	there	there	PRON
ecletica-1329	123	40	is	be	VERB
ecletica-1329	123	41	no	no	DET
ecletica-1329	123	42	direct	direct	ADJ
ecletica-1329	123	43	relationship	relationship	NOUN
ecletica-1329	123	44	between	between	ADP
ecletica-1329	123	45	the	the	DET
ecletica-1329	123	46	biological	biological	ADJ
ecletica-1329	123	47	activity	activity	NOUN
ecletica-1329	123	48	of	of	ADP
ecletica-1329	123	49	each	each	DET
ecletica-1329	123	50	compound	compound	NOUN
ecletica-1329	123	51	and	and	CCONJ
ecletica-1329	123	52	the	the	DET
ecletica-1329	123	53	descriptor	descriptor	NOUN
ecletica-1329	123	54	swaying	sway	VERB
ecletica-1329	123	55	the	the	DET
ecletica-1329	123	56	created	create	VERB
ecletica-1329	123	57	model	model	NOUN
ecletica-1329	123	58	is	be	AUX
ecletica-1329	123	59	rejected	reject	VERB
ecletica-1329	123	60	.	.	PUNCT
ecletica-1329	124	1	table	table	NOUN
ecletica-1329	124	2	5	5	NUM
ecletica-1329	124	3	.	.	PUNCT
ecletica-1329	125	1	statistical	statistical	ADJ
ecletica-1329	125	2	parameters	parameter	NOUN
ecletica-1329	125	3	that	that	PRON
ecletica-1329	125	4	affect	affect	VERB
ecletica-1329	125	5	the	the	DET
ecletica-1329	125	6	model	model	NOUN
ecletica-1329	125	7	.	.	PUNCT
ecletica-1329	126	1	descriptors	descriptor	NOUN
ecletica-1329	126	2	regression	regression	VERB
ecletica-1329	126	3	coefficient	coefficient	NOUN
ecletica-1329	126	4	p	p	X
ecletica-1329	126	5	–	–	PUNCT
ecletica-1329	126	6	value	value	NOUN
ecletica-1329	126	7	(	(	PUNCT
ecletica-1329	126	8	confidence	confidence	NOUN
ecletica-1329	126	9	interval	interval	NOUN
ecletica-1329	126	10	)	)	PUNCT
ecletica-1329	126	11	vif	vif	PROPN
ecletica-1329	126	12	standard	standard	NOUN
ecletica-1329	126	13	error	error	NOUN
ecletica-1329	126	14	dm	dm	NOUN
ecletica-1329	126	15	–	–	PUNCT
ecletica-1329	126	16	4.43867	4.43867	NUM
ecletica-1329	126	17	0.2580	0.2580	NUM
ecletica-1329	126	18	3.297	3.297	NUM
ecletica-1329	126	19	3.47832	3.47832	NUM
ecletica-1329	126	20	mw	mw	NOUN
ecletica-1329	126	21	–	–	PUNCT
ecletica-1329	126	22	0.31745	0.31745	NUM
ecletica-1329	126	23	0.5345	0.5345	NUM
ecletica-1329	126	24	3.541	3.541	NUM
ecletica-1329	126	25	0.476184	0.476184	NUM
ecletica-1329	126	26	hba	hba	NOUN
ecletica-1329	126	27	–	–	PUNCT
ecletica-1329	126	28	8.97918	8.97918	NUM
ecletica-1329	126	29	0.4406	0.4406	NUM
ecletica-1329	126	30	4.349	4.349	NUM
ecletica-1329	126	31	10.7244	10.7244	NUM
ecletica-1329	126	32	log	log	NOUN
ecletica-1329	126	33	p	p	NOUN
ecletica-1329	126	34	–	–	PUNCT
ecletica-1329	126	35	1.51775	1.51775	NUM
ecletica-1329	126	36	0.8604	0.8604	NUM
ecletica-1329	126	37	2.202	2.202	NUM
ecletica-1329	126	38	8.19602	8.19602	NUM
ecletica-1329	126	39	table	table	NOUN
ecletica-1329	126	40	6	6	NUM
ecletica-1329	126	41	.	.	PUNCT
ecletica-1329	127	1	coefficient	coefficient	NOUN
ecletica-1329	127	2	of	of	ADP
ecletica-1329	127	3	pearson	pearson	PROPN
ecletica-1329	127	4	’s	’s	PART
ecletica-1329	127	5	correlation	correlation	NOUN
ecletica-1329	127	6	for	for	ADP
ecletica-1329	127	7	descriptor	descriptor	NOUN
ecletica-1329	127	8	in	in	ADP
ecletica-1329	127	9	qsar	qsar	NOUN
ecletica-1329	127	10	model	model	NOUN
ecletica-1329	127	11	.	.	PUNCT
ecletica-1329	128	1	intercorrelation	intercorrelation	NOUN
ecletica-1329	128	2	constant	constant	ADJ
ecletica-1329	128	3	dm	dm	PROPN
ecletica-1329	128	4	mw	mw	NOUN
ecletica-1329	128	5	hba	hba	NOUN
ecletica-1329	128	6	log	log	NOUN
ecletica-1329	128	7	p	p	NOUN
ecletica-1329	128	8	constant	constant	ADJ
ecletica-1329	128	9	225.902	225.902	NUM
ecletica-1329	128	10	dm	dm	PROPN
ecletica-1329	128	11	–	–	PUNCT
ecletica-1329	128	12	10.9752	10.9752	NUM
ecletica-1329	128	13	1.29913	1.29913	NUM
ecletica-1329	128	14	mw	mw	NOUN
ecletica-1329	128	15	–	–	PUNCT
ecletica-1329	128	16	0.607345	0.607345	NUM
ecletica-1329	128	17	0.0415951	0.0415951	NUM
ecletica-1329	128	18	0.00386242	0.00386242	NUM
ecletica-1329	128	19	hba	hba	NOUN
ecletica-1329	128	20	20.7074	20.7074	NUM
ecletica-1329	128	21	–	–	PUNCT
ecletica-1329	128	22	2.59999	2.59999	NUM
ecletica-1329	128	23	–	–	PUNCT
ecletica-1329	128	24	0.197066	0.197066	NUM
ecletica-1329	128	25	11.9110	11.9110	NUM
ecletica-1329	128	26	log	log	NOUN
ecletica-1329	128	27	p	p	NOUN
ecletica-1329	128	28	–	–	PUNCT
ecletica-1329	128	29	12.6244	12.6244	NUM
ecletica-1329	128	30	0.728923	0.728923	NUM
ecletica-1329	128	31	–	–	PUNCT
ecletica-1329	128	32	0.0698522	0.0698522	NUM
ecletica-1329	128	33	4.41221	4.41221	NUM
ecletica-1329	128	34	10.2917	10.2917	NUM
ecletica-1329	128	35	3.2	3.2	NUM
ecletica-1329	128	36	molecular	molecular	ADJ
ecletica-1329	128	37	docking	docking	NOUN
ecletica-1329	128	38	studies	study	NOUN
ecletica-1329	128	39	molecular	molecular	ADJ
ecletica-1329	128	40	docking	docking	NOUN
ecletica-1329	128	41	technique	technique	NOUN
ecletica-1329	128	42	was	be	AUX
ecletica-1329	128	43	used	use	VERB
ecletica-1329	128	44	to	to	PART
ecletica-1329	128	45	recognize	recognize	VERB
ecletica-1329	128	46	the	the	DET
ecletica-1329	128	47	compounds	compound	NOUN
ecletica-1329	128	48	which	which	PRON
ecletica-1329	128	49	bind	bind	VERB
ecletica-1329	128	50	well	well	ADV
ecletica-1329	128	51	to	to	ADP
ecletica-1329	128	52	the	the	DET
ecletica-1329	128	53	egfr	egfr	ADJ
ecletica-1329	128	54	pocket	pocket	NOUN
ecletica-1329	128	55	.	.	PUNCT
ecletica-1329	129	1	all	all	DET
ecletica-1329	129	2	tested	test	VERB
ecletica-1329	129	3	compounds	compound	NOUN
ecletica-1329	129	4	had	have	VERB
ecletica-1329	129	5	strong	strong	ADJ
ecletica-1329	129	6	binding	bind	VERB
ecletica-1329	129	7	affinity	affinity	NOUN
ecletica-1329	129	8	with	with	ADP
ecletica-1329	129	9	the	the	DET
ecletica-1329	129	10	receptor	receptor	NOUN
ecletica-1329	129	11	.	.	PUNCT
ecletica-1329	130	1	they	they	PRON
ecletica-1329	130	2	perfectly	perfectly	ADV
ecletica-1329	130	3	fit	fit	VERB
ecletica-1329	130	4	into	into	ADP
ecletica-1329	130	5	the	the	DET
ecletica-1329	130	6	active	active	ADJ
ecletica-1329	130	7	site	site	NOUN
ecletica-1329	130	8	of	of	ADP
ecletica-1329	130	9	the	the	DET
ecletica-1329	130	10	receptor	receptor	NOUN
ecletica-1329	130	11	by	by	ADP
ecletica-1329	130	12	interacting	interact	VERB
ecletica-1329	130	13	with	with	ADP
ecletica-1329	130	14	the	the	DET
ecletica-1329	130	15	amino	amino	NOUN
ecletica-1329	130	16	acid	acid	NOUN
ecletica-1329	130	17	residue	residue	NOUN
ecletica-1329	130	18	in	in	ADP
ecletica-1329	130	19	the	the	DET
ecletica-1329	130	20	active	active	ADJ
ecletica-1329	130	21	site	site	NOUN
ecletica-1329	130	22	of	of	ADP
ecletica-1329	130	23	the	the	DET
ecletica-1329	130	24	receptor	receptor	NOUN
ecletica-1329	130	25	.	.	PUNCT
ecletica-1329	131	1	the	the	DET
ecletica-1329	131	2	protein	protein	NOUN
ecletica-1329	131	3	residues	residue	NOUN
ecletica-1329	131	4	involved	involve	VERB
ecletica-1329	131	5	in	in	ADP
ecletica-1329	131	6	the	the	DET
ecletica-1329	131	7	interaction	interaction	NOUN
ecletica-1329	131	8	,	,	PUNCT
ecletica-1329	131	9	types	type	NOUN
ecletica-1329	131	10	of	of	ADP
ecletica-1329	131	11	interaction	interaction	NOUN
ecletica-1329	131	12	involved	involve	VERB
ecletica-1329	131	13	,	,	PUNCT
ecletica-1329	131	14	distance	distance	NOUN
ecletica-1329	131	15	and	and	CCONJ
ecletica-1329	131	16	binding	bind	VERB
ecletica-1329	131	17	affinity	affinity	NOUN
ecletica-1329	131	18	obtained	obtain	VERB
ecletica-1329	131	19	for	for	ADP
ecletica-1329	131	20	each	each	DET
ecletica-1329	131	21	complex	complex	NOUN
ecletica-1329	131	22	formed	form	VERB
ecletica-1329	131	23	by	by	ADP
ecletica-1329	131	24	the	the	DET
ecletica-1329	131	25	studied	study	VERB
ecletica-1329	131	26	compounds	compound	NOUN
ecletica-1329	131	27	and	and	CCONJ
ecletica-1329	131	28	standard	standard	NOUN
ecletica-1329	131	29	were	be	AUX
ecletica-1329	131	30	displayed	display	VERB
ecletica-1329	131	31	in	in	ADP
ecletica-1329	131	32	tables	table	NOUN
ecletica-1329	131	33	7	7	NUM
ecletica-1329	131	34	and	and	CCONJ
ecletica-1329	131	35	8	8	NUM
ecletica-1329	131	36	.	.	PUNCT
ecletica-1329	132	1	the	the	DET
ecletica-1329	132	2	protein	protein	NOUN
ecletica-1329	132	3	residues	residue	NOUN
ecletica-1329	132	4	involved	involve	VERB
ecletica-1329	132	5	in	in	ADP
ecletica-1329	132	6	the	the	DET
ecletica-1329	132	7	interaction	interaction	NOUN
ecletica-1329	132	8	and	and	CCONJ
ecletica-1329	132	9	type	type	NOUN
ecletica-1329	132	10	of	of	ADP
ecletica-1329	132	11	interactions	interaction	NOUN
ecletica-1329	132	12	observed	observe	VERB
ecletica-1329	132	13	for	for	ADP
ecletica-1329	132	14	c14efgr	c14efgr	ADJ
ecletica-1329	132	15	complex	complex	NOUN
ecletica-1329	132	16	was	be	AUX
ecletica-1329	132	17	also	also	ADV
ecletica-1329	132	18	displayed	display	VERB
ecletica-1329	132	19	in	in	ADP
ecletica-1329	132	20	fig	fig	NOUN
ecletica-1329	132	21	.	.	PUNCT
ecletica-1329	133	1	3	3	X
ecletica-1329	133	2	.	.	X
ecletica-1329	134	1	the	the	DET
ecletica-1329	134	2	complexes	complex	NOUN
ecletica-1329	134	3	formed	form	VERB
ecletica-1329	134	4	by	by	ADP
ecletica-1329	134	5	4lrm	4lrm	NUM
ecletica-1329	134	6	receptor	receptor	NOUN
ecletica-1329	134	7	showed	show	VERB
ecletica-1329	134	8	good	good	ADJ
ecletica-1329	134	9	interactions	interaction	NOUN
ecletica-1329	134	10	(	(	PUNCT
ecletica-1329	134	11	fig	fig	NOUN
ecletica-1329	134	12	.	.	PUNCT
ecletica-1329	135	1	3	3	NUM
ecletica-1329	135	2	)	)	PUNCT
ecletica-1329	135	3	.	.	PUNCT
ecletica-1329	136	1	the	the	DET
ecletica-1329	136	2	tested	test	VERB
ecletica-1329	136	3	compounds	compound	NOUN
ecletica-1329	136	4	showed	show	VERB
ecletica-1329	136	5	binding	binding	ADJ
ecletica-1329	136	6	affinity	affinity	NOUN
ecletica-1329	136	7	ranging	range	VERB
ecletica-1329	136	8	from	from	ADP
ecletica-1329	136	9	–	–	PUNCT
ecletica-1329	136	10	4.6	4.6	NUM
ecletica-1329	136	11	to	to	PART
ecletica-1329	136	12	–	–	PUNCT
ecletica-1329	136	13	10.1	10.1	NUM
ecletica-1329	136	14	kcal	kcal	ADJ
ecletica-1329	136	15	mol–1	mol–1	NOUN
ecletica-1329	136	16	.	.	PUNCT
ecletica-1329	137	1	according	accord	VERB
ecletica-1329	137	2	to	to	ADP
ecletica-1329	137	3	adepoju	adepoju	PROPN
ecletica-1329	137	4	et	et	PROPN
ecletica-1329	137	5	al	al	PROPN
ecletica-1329	137	6	.	.	PROPN
ecletica-1329	138	1	(	(	PUNCT
ecletica-1329	138	2	2022	2022	NUM
ecletica-1329	138	3	)	)	PUNCT
ecletica-1329	138	4	,	,	PUNCT
ecletica-1329	138	5	the	the	PRON
ecletica-1329	138	6	lower	low	ADJ
ecletica-1329	138	7	the	the	DET
ecletica-1329	138	8	binding	bind	VERB
ecletica-1329	138	9	affinity	affinity	NOUN
ecletica-1329	138	10	value	value	NOUN
ecletica-1329	138	11	of	of	ADP
ecletica-1329	138	12	any	any	DET
ecletica-1329	138	13	compound	compound	NOUN
ecletica-1329	138	14	,	,	PUNCT
ecletica-1329	138	15	the	the	PRON
ecletica-1329	138	16	better	well	ADJ
ecletica-1329	138	17	the	the	DET
ecletica-1329	138	18	inhibiting	inhibit	VERB
ecletica-1329	138	19	ability	ability	NOUN
ecletica-1329	138	20	of	of	ADP
ecletica-1329	138	21	such	such	ADJ
ecletica-1329	138	22	compound	compound	NOUN
ecletica-1329	138	23	;	;	PUNCT
ecletica-1329	138	24	thus	thus	ADV
ecletica-1329	138	25	,	,	PUNCT
ecletica-1329	138	26	compound	compound	NOUN
ecletica-1329	138	27	c14	c14	NOUN
ecletica-1329	138	28	with	with	ADP
ecletica-1329	138	29	–	–	PUNCT
ecletica-1329	138	30	10.1	10.1	NUM
ecletica-1329	138	31	kcal	kcal	NOUN
ecletica-1329	138	32	mol–1	mol–1	NOUN
ecletica-1329	138	33	was	be	AUX
ecletica-1329	138	34	observed	observe	VERB
ecletica-1329	138	35	to	to	PART
ecletica-1329	138	36	have	have	VERB
ecletica-1329	138	37	highest	high	ADJ
ecletica-1329	138	38	tendency	tendency	NOUN
ecletica-1329	138	39	to	to	PART
ecletica-1329	138	40	inhibit	inhibit	VERB
ecletica-1329	138	41	the	the	DET
ecletica-1329	138	42	studied	studied	ADJ
ecletica-1329	138	43	receptor	receptor	NOUN
ecletica-1329	138	44	than	than	ADP
ecletica-1329	138	45	other	other	ADJ
ecletica-1329	138	46	studied	study	VERB
ecletica-1329	138	47	compounds	compound	NOUN
ecletica-1329	138	48	.	.	PUNCT
ecletica-1329	139	1	pi	pi	NOUN
ecletica-1329	139	2	-	-	PUNCT
ecletica-1329	139	3	anion	anion	NOUN
ecletica-1329	139	4	interaction	interaction	NOUN
ecletica-1329	139	5	was	be	AUX
ecletica-1329	139	6	observed	observe	VERB
ecletica-1329	139	7	in	in	ADP
ecletica-1329	139	8	all	all	DET
ecletica-1329	139	9	the	the	DET
ecletica-1329	139	10	complexes	complex	NOUN
ecletica-1329	139	11	except	except	SCONJ
ecletica-1329	139	12	in	in	ADP
ecletica-1329	139	13	compounds	compound	NOUN
ecletica-1329	139	14	c5	c5	PROPN
ecletica-1329	139	15	,	,	PUNCT
ecletica-1329	139	16	c7	c7	PROPN
ecletica-1329	139	17	,	,	PUNCT
ecletica-1329	139	18	c8	c8	PROPN
ecletica-1329	139	19	,	,	PUNCT
ecletica-1329	139	20	and	and	CCONJ
ecletica-1329	139	21	c9	c9	NOUN
ecletica-1329	139	22	.	.	PUNCT
ecletica-1329	140	1	a	a	DET
ecletica-1329	140	2	salt	salt	NOUN
ecletica-1329	140	3	bridge	bridge	NOUN
ecletica-1329	140	4	was	be	AUX
ecletica-1329	140	5	formed	form	VERB
ecletica-1329	140	6	between	between	ADP
ecletica-1329	140	7	asp858	asp858	PROPN
ecletica-1329	140	8	,	,	PUNCT
ecletica-1329	140	9	and	and	CCONJ
ecletica-1329	140	10	the	the	DET
ecletica-1329	140	11	nitro	nitro	NOUN
ecletica-1329	140	12	group	group	NOUN
ecletica-1329	140	13	of	of	ADP
ecletica-1329	140	14	the	the	DET
ecletica-1329	140	15	ligand	ligand	NOUN
ecletica-1329	140	16	in	in	ADP
ecletica-1329	140	17	complex	complex	NOUN
ecletica-1329	140	18	formed	form	VERB
ecletica-1329	140	19	by	by	ADP
ecletica-1329	140	20	compound	compound	NOUN
ecletica-1329	140	21	c12	c12	PROPN
ecletica-1329	140	22	.	.	PUNCT
ecletica-1329	140	23	complexes	complex	NOUN
ecletica-1329	140	24	formed	form	VERB
ecletica-1329	140	25	by	by	ADP
ecletica-1329	140	26	compound	compound	NOUN
ecletica-1329	140	27	c4	c4	PROPN
ecletica-1329	140	28	,	,	PUNCT
ecletica-1329	140	29	c6	c6	PROPN
ecletica-1329	140	30	,	,	PUNCT
ecletica-1329	140	31	c8	c8	PROPN
ecletica-1329	140	32	,	,	PUNCT
ecletica-1329	140	33	c11	c11	NOUN
ecletica-1329	140	34	,	,	PUNCT
ecletica-1329	140	35	and	and	CCONJ
ecletica-1329	140	36	c14	c14	NOUN
ecletica-1329	140	37	showed	show	VERB
ecletica-1329	140	38	a	a	DET
ecletica-1329	140	39	pi	pi	NOUN
ecletica-1329	140	40	-	-	PUNCT
ecletica-1329	140	41	sulfur	sulfur	NOUN
ecletica-1329	140	42	interaction	interaction	NOUN
ecletica-1329	140	43	between	between	ADP
ecletica-1329	140	44	cys800	cys800	PROPN
ecletica-1329	140	45	and	and	CCONJ
ecletica-1329	140	46	the	the	DET
ecletica-1329	140	47	respective	respective	ADJ
ecletica-1329	140	48	ligands	ligand	NOUN
ecletica-1329	140	49	.	.	PUNCT
ecletica-1329	141	1	pi	pi	NOUN
ecletica-1329	141	2	-	-	PUNCT
ecletica-1329	141	3	sigma	sigma	PROPN
ecletica-1329	141	4	bond	bond	NOUN
ecletica-1329	141	5	was	be	AUX
ecletica-1329	141	6	observed	observe	VERB
ecletica-1329	141	7	for	for	ADP
ecletica-1329	141	8	all	all	DET
ecletica-1329	141	9	complexes	complex	NOUN
ecletica-1329	141	10	except	except	SCONJ
ecletica-1329	141	11	for	for	ADP
ecletica-1329	141	12	complexes	complex	NOUN
ecletica-1329	141	13	formed	form	VERB
ecletica-1329	141	14	by	by	ADP
ecletica-1329	141	15	c2	c2	PROPN
ecletica-1329	141	16	,	,	PUNCT
ecletica-1329	141	17	c5	c5	PROPN
ecletica-1329	141	18	,	,	PUNCT
ecletica-1329	141	19	c9	c9	NOUN
ecletica-1329	141	20	,	,	PUNCT
ecletica-1329	141	21	c12	c12	PROPN
ecletica-1329	141	22	and	and	CCONJ
ecletica-1329	141	23	c13	c13	PROPN
ecletica-1329	141	24	.	.	PUNCT
ecletica-1329	142	1	only	only	ADV
ecletica-1329	142	2	the	the	DET
ecletica-1329	142	3	complex	complex	NOUN
ecletica-1329	142	4	formed	form	VERB
ecletica-1329	142	5	by	by	ADP
ecletica-1329	142	6	c14	c14	PROPN
ecletica-1329	142	7	had	have	VERB
ecletica-1329	142	8	unfavorable	unfavorable	ADJ
ecletica-1329	142	9	acceptor	acceptor	NOUN
ecletica-1329	142	10	-	-	PUNCT
ecletica-1329	142	11	acceptor	acceptor	NOUN
ecletica-1329	142	12	interaction	interaction	NOUN
ecletica-1329	142	13	.	.	PUNCT
ecletica-1329	143	1	complexes	complex	NOUN
ecletica-1329	143	2	formed	form	VERB
ecletica-1329	143	3	by	by	ADP
ecletica-1329	143	4	compound	compound	PROPN
ecletica-1329	143	5	c2	c2	PROPN
ecletica-1329	143	6	,	,	PUNCT
ecletica-1329	143	7	c5	c5	PROPN
ecletica-1329	143	8	,	,	PUNCT
ecletica-1329	143	9	c9	c9	PROPN
ecletica-1329	143	10	,	,	PUNCT
ecletica-1329	143	11	c10	c10	PROPN
ecletica-1329	143	12	,	,	PUNCT
ecletica-1329	143	13	c11	c11	NOUN
ecletica-1329	143	14	,	,	PUNCT
ecletica-1329	143	15	c12	c12	PROPN
ecletica-1329	143	16	,	,	PUNCT
ecletica-1329	143	17	and	and	CCONJ
ecletica-1329	143	18	c14	c14	NOUN
ecletica-1329	143	19	showed	show	VERB
ecletica-1329	143	20	a	a	DET
ecletica-1329	143	21	conventional	conventional	ADJ
ecletica-1329	143	22	hydrogen	hydrogen	NOUN
ecletica-1329	143	23	bond	bond	NOUN
ecletica-1329	143	24	while	while	SCONJ
ecletica-1329	143	25	others	other	NOUN
ecletica-1329	143	26	do	do	VERB
ecletica-1329	143	27	not	not	PART
ecletica-1329	143	28	.	.	PUNCT
ecletica-1329	144	1	other	other	ADJ
ecletica-1329	144	2	interactions	interaction	NOUN
ecletica-1329	144	3	observed	observe	VERB
ecletica-1329	144	4	in	in	ADP
ecletica-1329	144	5	the	the	DET
ecletica-1329	144	6	complexes	complex	NOUN
ecletica-1329	144	7	are	be	AUX
ecletica-1329	144	8	carbon	carbon	NOUN
ecletica-1329	144	9	hydrogen	hydrogen	NOUN
ecletica-1329	144	10	bond	bond	NOUN
ecletica-1329	144	11	,	,	PUNCT
ecletica-1329	144	12	pi	pi	NOUN
ecletica-1329	144	13	-	-	PUNCT
ecletica-1329	144	14	pi	pi	NOUN
ecletica-1329	144	15	stacked	stack	VERB
ecletica-1329	144	16	,	,	PUNCT
ecletica-1329	144	17	alkyl	alkyl	NOUN
ecletica-1329	144	18	and	and	CCONJ
ecletica-1329	144	19	pi	pi	NOUN
ecletica-1329	144	20	-	-	PUNCT
ecletica-1329	144	21	alkyl	alkyl	ADJ
ecletica-1329	144	22	(	(	PUNCT
ecletica-1329	144	23	table	table	NOUN
ecletica-1329	144	24	7	7	NUM
ecletica-1329	144	25	)	)	PUNCT
ecletica-1329	144	26	.	.	PUNCT
ecletica-1329	145	1	https://revista.iq.unesp.br/index.php/ecletica	https://revista.iq.unesp.br/index.php/ecletica	PROPN
ecletica-1329	145	2	https://doi.org/10.26850/1678-4618eqj.v48.1.2023.p55-71	https://doi.org/10.26850/1678-4618eqj.v48.1.2023.p55-71	PROPN
ecletica-1329	145	3	original	original	ADJ
ecletica-1329	145	4	article	article	NOUN
ecletica-1329	145	5	revista.iq.unesp.br	revista.iq.unesp.br	PROPN
ecletica-1329	145	6	64	64	NUM
ecletica-1329	145	7	eclética	eclética	PROPN
ecletica-1329	145	8	química	química	PROPN
ecletica-1329	145	9	,	,	PUNCT
ecletica-1329	145	10	vol	vol	NOUN
ecletica-1329	145	11	.	.	PROPN
ecletica-1329	145	12	48	48	NUM
ecletica-1329	145	13	,	,	PUNCT
ecletica-1329	145	14	n.	n.	NOUN
ecletica-1329	145	15	1	1	NUM
ecletica-1329	145	16	,	,	PUNCT
ecletica-1329	145	17	2023	2023	NUM
ecletica-1329	145	18	,	,	PUNCT
ecletica-1329	145	19	55	55	NUM
ecletica-1329	145	20	-	-	SYM
ecletica-1329	145	21	71	71	NUM
ecletica-1329	145	22	issn	issn	NOUN
ecletica-1329	145	23	:	:	PUNCT
ecletica-1329	145	24	1678	1678	NUM
ecletica-1329	145	25	-	-	SYM
ecletica-1329	145	26	4618	4618	NUM
ecletica-1329	145	27	doi	doi	NOUN
ecletica-1329	145	28	:	:	PUNCT
ecletica-1329	145	29	10.26850/1678	10.26850/1678	NUM
ecletica-1329	145	30	-	-	PUNCT
ecletica-1329	145	31	4618eqj.v48.1.2023.p55	4618eqj.v48.1.2023.p55	NUM
ecletica-1329	145	32	-	-	PUNCT
ecletica-1329	145	33	71	71	NUM
ecletica-1329	145	34	table	table	NOUN
ecletica-1329	145	35	7	7	NUM
ecletica-1329	145	36	.	.	PUNCT
ecletica-1329	146	1	binding	bind	VERB
ecletica-1329	146	2	interactions	interaction	NOUN
ecletica-1329	146	3	and	and	CCONJ
ecletica-1329	146	4	binding	bind	VERB
ecletica-1329	146	5	affinity	affinity	NOUN
ecletica-1329	146	6	between	between	ADP
ecletica-1329	146	7	ligands	ligand	NOUN
ecletica-1329	146	8	and	and	CCONJ
ecletica-1329	146	9	receptor	receptor	NOUN
ecletica-1329	146	10	4lrm	4lrm	NOUN
ecletica-1329	146	11	.	.	PUNCT
ecletica-1329	147	1	hydrogen	hydrogen	NOUN
ecletica-1329	147	2	interaction	interaction	NOUN
ecletica-1329	147	3	hydrophobic	hydrophobic	NOUN
ecletica-1329	147	4	interaction	interaction	NOUN
ecletica-1329	147	5	∆g	∆g	PROPN
ecletica-1329	147	6	(	(	PUNCT
ecletica-1329	147	7	kcal	kcal	X
ecletica-1329	147	8	mol–1	mol–1	NOUN
ecletica-1329	147	9	)	)	PUNCT
ecletica-1329	147	10	c1	c1	PROPN
ecletica-1329	147	11	thr793	thr793	PROPN
ecletica-1329	147	12	,	,	PUNCT
ecletica-1329	147	13	ala743	ala743	PROPN
ecletica-1329	147	14	,	,	PUNCT
ecletica-1329	147	15	cys800	cys800	PROPN
ecletica-1329	147	16	,	,	PUNCT
ecletica-1329	147	17	ser720	ser720	PROPN
ecletica-1329	147	18	,	,	PUNCT
ecletica-1329	147	19	gly724	gly724	PROPN
ecletica-1329	147	20	,	,	PUNCT
ecletica-1329	147	21	gly719	gly719	PROPN
ecletica-1329	147	22	,	,	PUNCT
ecletica-1329	147	23	arg844	arg844	PROPN
ecletica-1329	147	24	,	,	PUNCT
ecletica-1329	147	25	asn845	asn845	PROPN
ecletica-1329	147	26	,	,	PUNCT
ecletica-1329	147	27	asp858	asp858	PROPN
ecletica-1329	147	28	,	,	PUNCT
ecletica-1329	147	29	lys745	lys745	ADV
ecletica-1329	147	30	,	,	PUNCT
ecletica-1329	147	31	glu762	glu762	PROPN
ecletica-1329	147	32	,	,	PUNCT
ecletica-1329	147	33	leu718	leu718	PROPN
ecletica-1329	147	34	,	,	PUNCT
ecletica-1329	147	35	thr857	thr857	PROPN
ecletica-1329	147	36	,	,	PUNCT
ecletica-1329	147	37	met766	met766	PROPN
ecletica-1329	147	38	,	,	PUNCT
ecletica-1329	147	39	leu847	leu847	PROPN
ecletica-1329	147	40	,	,	PUNCT
ecletica-1329	147	41	val726	val726	NOUN
ecletica-1329	147	42	–	–	PUNCT
ecletica-1329	147	43	8.4	8.4	NUM
ecletica-1329	147	44	c2	c2	PROPN
ecletica-1329	147	45	glu762	glu762	PROPN
ecletica-1329	147	46	,	,	PUNCT
ecletica-1329	147	47	asp858	asp858	PROPN
ecletica-1329	147	48	leu847	leu847	PROPN
ecletica-1329	147	49	,	,	PUNCT
ecletica-1329	147	50	thr793	thr793	PROPN
ecletica-1329	147	51	,	,	PUNCT
ecletica-1329	147	52	thr857	thr857	PROPN
ecletica-1329	147	53	,	,	PUNCT
ecletica-1329	147	54	met766	met766	PROPN
ecletica-1329	147	55	,	,	PUNCT
ecletica-1329	147	56	leu791	leu791	PROPN
ecletica-1329	147	57	,	,	PUNCT
ecletica-1329	147	58	lys745	lys745	PROPN
ecletica-1329	147	59	,	,	PUNCT
ecletica-1329	147	60	phe859	phe859	PROPN
ecletica-1329	147	61	,	,	PUNCT
ecletica-1329	147	62	ser720	ser720	PROPN
ecletica-1329	147	63	,	,	PUNCT
ecletica-1329	147	64	gly719	gly719	PROPN
ecletica-1329	147	65	,	,	PUNCT
ecletica-1329	147	66	gly724	gly724	PROPN
ecletica-1329	147	67	,	,	PUNCT
ecletica-1329	147	68	arg844	arg844	PROPN
ecletica-1329	147	69	,	,	PUNCT
ecletica-1329	147	70	phe723	phe723	PROPN
ecletica-1329	147	71	,	,	PUNCT
ecletica-1329	147	72	asn845	asn845	PROPN
ecletica-1329	147	73	,	,	PUNCT
ecletica-1329	147	74	ala743	ala743	PROPN
ecletica-1329	147	75	,	,	PUNCT
ecletica-1329	147	76	val726	val726	PROPN
ecletica-1329	147	77	,	,	PUNCT
ecletica-1329	147	78	leu718	leu718	PROPN
ecletica-1329	147	79	,	,	PUNCT
ecletica-1329	147	80	–	–	PUNCT
ecletica-1329	147	81	8.1	8.1	NUM
ecletica-1329	147	82	c3	c3	PROPN
ecletica-1329	147	83	ala743	ala743	PROPN
ecletica-1329	147	84	,	,	PUNCT
ecletica-1329	147	85	val726	val726	PROPN
ecletica-1329	147	86	,	,	PUNCT
ecletica-1329	147	87	leu847	leu847	PROPN
ecletica-1329	147	88	,	,	PUNCT
ecletica-1329	147	89	leu718	leu718	PROPN
ecletica-1329	147	90	,	,	PUNCT
ecletica-1329	147	91	gly799	gly799	PROPN
ecletica-1329	147	92	,	,	PUNCT
ecletica-1329	147	93	cys800	cys800	PROPN
ecletica-1329	147	94	,	,	PUNCT
ecletica-1329	147	95	gly719	gly719	PROPN
ecletica-1329	147	96	,	,	PUNCT
ecletica-1329	147	97	arg844	arg844	PROPN
ecletica-1329	147	98	,	,	PUNCT
ecletica-1329	147	99	ser720	ser720	PROPN
ecletica-1329	147	100	,	,	PUNCT
ecletica-1329	147	101	gly721	gly721	PROPN
ecletica-1329	147	102	,	,	PUNCT
ecletica-1329	147	103	phe723	phe723	PROPN
ecletica-1329	147	104	,	,	PUNCT
ecletica-1329	147	105	gly724	gly724	PROPN
ecletica-1329	147	106	,	,	PUNCT
ecletica-1329	147	107	asp858	asp858	PROPN
ecletica-1329	147	108	,	,	PUNCT
ecletica-1329	147	109	asn854	asn854	PROPN
ecletica-1329	147	110	,	,	PUNCT
ecletica-1329	147	111	lys745	lys745	PROPN
ecletica-1329	147	112	,	,	PUNCT
ecletica-1329	147	113	met766	met766	NOUN
ecletica-1329	147	114	,	,	PUNCT
ecletica-1329	147	115	thr857	thr857	PROPN
ecletica-1329	147	116	,	,	PUNCT
ecletica-1329	147	117	thr793	thr793	PROPN
ecletica-1329	147	118	,	,	PUNCT
ecletica-1329	147	119	–	–	PUNCT
ecletica-1329	147	120	8.2	8.2	NUM
ecletica-1329	147	121	c4	c4	NOUN
ecletica-1329	147	122	thr857	thr857	PROPN
ecletica-1329	147	123	,	,	PUNCT
ecletica-1329	147	124	thr793	thr793	PROPN
ecletica-1329	147	125	,	,	PUNCT
ecletica-1329	147	126	val726	val726	PROPN
ecletica-1329	147	127	,	,	PUNCT
ecletica-1329	147	128	leu718	leu718	PROPN
ecletica-1329	147	129	,	,	PUNCT
ecletica-1329	147	130	gly799	gly799	PROPN
ecletica-1329	147	131	,	,	PUNCT
ecletica-1329	147	132	leu847	leu847	PROPN
ecletica-1329	147	133	,	,	PUNCT
ecletica-1329	147	134	gly719	gly719	PROPN
ecletica-1329	147	135	,	,	PUNCT
ecletica-1329	147	136	cys800	cys800	PROPN
ecletica-1329	147	137	,	,	PUNCT
ecletica-1329	147	138	ser720	ser720	PROPN
ecletica-1329	147	139	,	,	PUNCT
ecletica-1329	147	140	arg844	arg844	PROPN
ecletica-1329	147	141	,	,	PUNCT
ecletica-1329	147	142	leu802	leu802	PROPN
ecletica-1329	147	143	,	,	PUNCT
ecletica-1329	147	144	gly724	gly724	PROPN
ecletica-1329	147	145	,	,	PUNCT
ecletica-1329	147	146	asp803	asp803	PROPN
ecletica-1329	147	147	,	,	PUNCT
ecletica-1329	147	148	phe723	phe723	PROPN
ecletica-1329	147	149	,	,	PUNCT
ecletica-1329	147	150	asp840	asp840	PROPN
ecletica-1329	147	151	,	,	PUNCT
ecletica-1329	147	152	asp858	asp858	PROPN
ecletica-1329	147	153	,	,	PUNCT
ecletica-1329	147	154	asn845	asn845	PROPN
ecletica-1329	147	155	,	,	PUNCT
ecletica-1329	147	156	lys745	lys745	ADV
ecletica-1329	147	157	–	–	PUNCT
ecletica-1329	147	158	8.7	8.7	NUM
ecletica-1329	147	159	c5	c5	PROPN
ecletica-1329	147	160	asp858	asp858	PROPN
ecletica-1329	147	161	,	,	PUNCT
ecletica-1329	147	162	lys745	lys745	ADV
ecletica-1329	147	163	lys878	lys878	PROPN
ecletica-1329	147	164	,	,	PUNCT
ecletica-1329	147	165	phe723	phe723	ADJ
ecletica-1329	147	166	,	,	PUNCT
ecletica-1329	147	167	val879	val879	ADJ
ecletica-1329	147	168	,	,	PUNCT
ecletica-1329	147	169	pro880	pro880	PROPN
ecletica-1329	147	170	,	,	PUNCT
ecletica-1329	147	171	asp840	asp840	NOUN
ecletica-1329	147	172	,	,	PUNCT
ecletica-1329	147	173	leu861	leu861	PROPN
ecletica-1329	147	174	,	,	PUNCT
ecletica-1329	147	175	gly860	gly860	PROPN
ecletica-1329	147	176	,	,	PUNCT
ecletica-1329	147	177	glu762	glu762	PROPN
ecletica-1329	147	178	,	,	PUNCT
ecletica-1329	147	179	ala755	ala755	PROPN
ecletica-1329	147	180	,	,	PUNCT
ecletica-1329	147	181	ile759	ile759	ADJ
ecletica-1329	147	182	,	,	PUNCT
ecletica-1329	147	183	leu747	leu747	PROPN
ecletica-1329	147	184	,	,	PUNCT
ecletica-1329	147	185	glu758	glu758	PROPN
ecletica-1329	147	186	,	,	PUNCT
ecletica-1329	147	187	lys754	lys754	PROPN
ecletica-1329	147	188	,	,	PUNCT
ecletica-1329	147	189	ala722	ala722	PROPN
ecletica-1329	147	190	,	,	PUNCT
ecletica-1329	147	191	–	–	PUNCT
ecletica-1329	147	192	8.0	8.0	NUM
ecletica-1329	147	193	c6	c6	PROPN
ecletica-1329	147	194	arg844	arg844	PROPN
ecletica-1329	147	195	,	,	PUNCT
ecletica-1329	147	196	asp803	asp803	PROPN
ecletica-1329	147	197	,	,	PUNCT
ecletica-1329	147	198	cys800	cys800	PROPN
ecletica-1329	147	199	,	,	PUNCT
ecletica-1329	147	200	gly719	gly719	PROPN
ecletica-1329	147	201	,	,	PUNCT
ecletica-1329	147	202	asn845	asn845	PROPN
ecletica-1329	147	203	,	,	PUNCT
ecletica-1329	147	204	leu847	leu847	PROPN
ecletica-1329	147	205	,	,	PUNCT
ecletica-1329	147	206	val726	val726	PROPN
ecletica-1329	147	207	,	,	PUNCT
ecletica-1329	147	208	ala743	ala743	PROPN
ecletica-1329	147	209	,	,	PUNCT
ecletica-1329	147	210	leu718	leu718	PROPN
ecletica-1329	147	211	,	,	PUNCT
ecletica-1329	147	212	thr857	thr857	PROPN
ecletica-1329	147	213	,	,	PUNCT
ecletica-1329	147	214	lys745	lys745	PROPN
ecletica-1329	147	215	,	,	PUNCT
ecletica-1329	147	216	asp840	asp840	PROPN
ecletica-1329	147	217	,	,	PUNCT
ecletica-1329	147	218	phe723	phe723	PROPN
ecletica-1329	147	219	,	,	PUNCT
ecletica-1329	147	220	gly724	gly724	PROPN
ecletica-1329	147	221	,	,	PUNCT
ecletica-1329	147	222	asp858	asp858	PROPN
ecletica-1329	147	223	,	,	PUNCT
ecletica-1329	147	224	ser720	ser720	PROPN
ecletica-1329	147	225	,	,	PUNCT
ecletica-1329	147	226	gly721	gly721	PROPN
ecletica-1329	147	227	–	–	PUNCT
ecletica-1329	147	228	7.8	7.8	NUM
ecletica-1329	147	229	c7	c7	PROPN
ecletica-1329	147	230	asp803	asp803	PROPN
ecletica-1329	147	231	,	,	PUNCT
ecletica-1329	147	232	arg844	arg844	PROPN
ecletica-1329	147	233	,	,	PUNCT
ecletica-1329	147	234	leu802	leu802	PROPN
ecletica-1329	147	235	,	,	PUNCT
ecletica-1329	147	236	cys800	cys800	PROPN
ecletica-1329	147	237	,	,	PUNCT
ecletica-1329	147	238	glu762	glu762	PROPN
ecletica-1329	147	239	,	,	PUNCT
ecletica-1329	147	240	thr857	thr857	PROPN
ecletica-1329	147	241	,	,	PUNCT
ecletica-1329	147	242	leu847	leu847	PROPN
ecletica-1329	147	243	,	,	PUNCT
ecletica-1329	147	244	val726	val726	PROPN
ecletica-1329	147	245	,	,	PUNCT
ecletica-1329	147	246	leu718	leu718	PROPN
ecletica-1329	147	247	,	,	PUNCT
ecletica-1329	147	248	asp858	asp858	PROPN
ecletica-1329	147	249	,	,	PUNCT
ecletica-1329	147	250	lys745	lys745	PROPN
ecletica-1329	147	251	,	,	PUNCT
ecletica-1329	147	252	gly719	gly719	PROPN
ecletica-1329	147	253	,	,	PUNCT
ecletica-1329	147	254	thr725	thr725	PROPN
ecletica-1329	147	255	,	,	PUNCT
ecletica-1329	147	256	gly724	gly724	PROPN
ecletica-1329	147	257	,	,	PUNCT
ecletica-1329	147	258	ser720	ser720	PROPN
ecletica-1329	147	259	,	,	PUNCT
ecletica-1329	147	260	phe723	phe723	PROPN
ecletica-1329	147	261	,	,	PUNCT
ecletica-1329	147	262	gly721	gly721	PROPN
ecletica-1329	147	263	7.6	7.6	NUM
ecletica-1329	147	264	c8	c8	PROPN
ecletica-1329	147	265	arg844	arg844	PROPN
ecletica-1329	147	266	,	,	PUNCT
ecletica-1329	147	267	asp803	asp803	PROPN
ecletica-1329	147	268	,	,	PUNCT
ecletica-1329	147	269	leu802	leu802	PROPN
ecletica-1329	147	270	,	,	PUNCT
ecletica-1329	147	271	cys800	cys800	PROPN
ecletica-1329	147	272	,	,	PUNCT
ecletica-1329	147	273	gly762	gly762	PROPN
ecletica-1329	147	274	,	,	PUNCT
ecletica-1329	147	275	lys	lys	NOUN
ecletica-1329	147	276	745	745	NUM
ecletica-1329	147	277	,	,	PUNCT
ecletica-1329	147	278	thr857	thr857	PROPN
ecletica-1329	147	279	,	,	PUNCT
ecletica-1329	147	280	val726	val726	PROPN
ecletica-1329	147	281	,	,	PUNCT
ecletica-1329	147	282	leu847	leu847	PROPN
ecletica-1329	147	283	,	,	PUNCT
ecletica-1329	147	284	leu718	leu718	PROPN
ecletica-1329	147	285	,	,	PUNCT
ecletica-1329	147	286	asp856	asp856	PROPN
ecletica-1329	147	287	,	,	PUNCT
ecletica-1329	147	288	gly719	gly719	PROPN
ecletica-1329	147	289	,	,	PUNCT
ecletica-1329	147	290	gly724	gly724	PROPN
ecletica-1329	147	291	,	,	PUNCT
ecletica-1329	147	292	phe723	phe723	PROPN
ecletica-1329	147	293	,	,	PUNCT
ecletica-1329	147	294	asp840	asp840	PROPN
ecletica-1329	147	295	,	,	PUNCT
ecletica-1329	147	296	asn845	asn845	PROPN
ecletica-1329	147	297	,	,	PUNCT
ecletica-1329	147	298	ser720	ser720	PROPN
ecletica-1329	147	299	,	,	PUNCT
ecletica-1329	147	300	gly721	gly721	PROPN
ecletica-1329	147	301	–	–	PUNCT
ecletica-1329	147	302	8.4	8.4	NUM
ecletica-1329	147	303	c9	c9	PROPN
ecletica-1329	147	304	thr793	thr793	PROPN
ecletica-1329	147	305	,	,	PUNCT
ecletica-1329	147	306	lys745	lys745	PROPN
ecletica-1329	147	307	met766	met766	PROPN
ecletica-1329	147	308	,	,	PUNCT
ecletica-1329	147	309	thr793	thr793	PROPN
ecletica-1329	147	310	,	,	PUNCT
ecletica-1329	147	311	asp858	asp858	PROPN
ecletica-1329	147	312	,	,	PUNCT
ecletica-1329	147	313	gly724	gly724	PROPN
ecletica-1329	147	314	,	,	PUNCT
ecletica-1329	147	315	asn845	asn845	PROPN
ecletica-1329	147	316	,	,	PUNCT
ecletica-1329	147	317	arg844	arg844	PROPN
ecletica-1329	147	318	,	,	PUNCT
ecletica-1329	147	319	phe723	phe723	PROPN
ecletica-1329	147	320	,	,	PUNCT
ecletica-1329	147	321	asp840	asp840	PROPN
ecletica-1329	147	322	,	,	PUNCT
ecletica-1329	147	323	gly721	gly721	PROPN
ecletica-1329	147	324	,	,	PUNCT
ecletica-1329	147	325	ser720	ser720	PROPN
ecletica-1329	147	326	,	,	PUNCT
ecletica-1329	147	327	gly719	gly719	PROPN
ecletica-1329	147	328	,	,	PUNCT
ecletica-1329	147	329	val726	val726	PROPN
ecletica-1329	147	330	,	,	PUNCT
ecletica-1329	147	331	cys800	cys800	PROPN
ecletica-1329	147	332	,	,	PUNCT
ecletica-1329	147	333	leu718	leu718	PROPN
ecletica-1329	147	334	,	,	PUNCT
ecletica-1329	147	335	leu847	leu847	PROPN
ecletica-1329	147	336	,	,	PUNCT
ecletica-1329	147	337	aa743	aa743	PROPN
ecletica-1329	147	338	,	,	PUNCT
ecletica-1329	147	339	thr857	thr857	PROPN
ecletica-1329	147	340	–	–	PUNCT
ecletica-1329	147	341	8.4	8.4	NUM
ecletica-1329	147	342	c10	c10	PROPN
ecletica-1329	147	343	gln794	gln794	PROPN
ecletica-1329	147	344	,	,	PUNCT
ecletica-1329	147	345	met796	met796	PROPN
ecletica-1329	147	346	leu795	leu795	PROPN
ecletica-1329	147	347	,	,	PUNCT
ecletica-1329	147	348	leu718	leu718	PROPN
ecletica-1329	147	349	,	,	PUNCT
ecletica-1329	147	350	leu847	leu847	PROPN
ecletica-1329	147	351	,	,	PUNCT
ecletica-1329	147	352	cys800	cys800	PROPN
ecletica-1329	147	353	,	,	PUNCT
ecletica-1329	147	354	gly719	gly719	PROPN
ecletica-1329	147	355	,	,	PUNCT
ecletica-1329	147	356	ser720	ser720	PROPN
ecletica-1329	147	357	,	,	PUNCT
ecletica-1329	147	358	gly724	gly724	PROPN
ecletica-1329	147	359	,	,	PUNCT
ecletica-1329	147	360	arg844	arg844	PROPN
ecletica-1329	147	361	,	,	PUNCT
ecletica-1329	147	362	phe723	phe723	PROPN
ecletica-1329	147	363	,	,	PUNCT
ecletica-1329	147	364	asp858	asp858	PROPN
ecletica-1329	147	365	,	,	PUNCT
ecletica-1329	147	366	asn845	asn845	PROPN
ecletica-1329	147	367	,	,	PUNCT
ecletica-1329	147	368	glu762	glu762	PROPN
ecletica-1329	147	369	,	,	PUNCT
ecletica-1329	147	370	lys745	lys745	ADV
ecletica-1329	147	371	,	,	PUNCT
ecletica-1329	147	372	met766	met766	NOUN
ecletica-1329	147	373	,	,	PUNCT
ecletica-1329	147	374	thr857	thr857	PROPN
ecletica-1329	147	375	,	,	PUNCT
ecletica-1329	147	376	val726	val726	PROPN
ecletica-1329	147	377	,	,	PUNCT
ecletica-1329	147	378	al743	al743	PROPN
ecletica-1329	147	379	,	,	PUNCT
ecletica-1329	147	380	thr793	thr793	PROPN
ecletica-1329	147	381	–	–	PUNCT
ecletica-1329	147	382	6.9	6.9	NUM
ecletica-1329	147	383	c11	c11	NOUN
ecletica-1329	147	384	glu762	glu762	NOUN
ecletica-1329	147	385	,	,	PUNCT
ecletica-1329	147	386	lys745	lys745	ADV
ecletica-1329	147	387	,	,	PUNCT
ecletica-1329	147	388	val726	val726	PROPN
ecletica-1329	147	389	,	,	PUNCT
ecletica-1329	147	390	met766	met766	PROPN
ecletica-1329	147	391	,	,	PUNCT
ecletica-1329	147	392	thr793	thr793	PROPN
ecletica-1329	147	393	,	,	PUNCT
ecletica-1329	147	394	ala743	ala743	PROPN
ecletica-1329	147	395	,	,	PUNCT
ecletica-1329	147	396	thr857	thr857	PROPN
ecletica-1329	147	397	,	,	PUNCT
ecletica-1329	147	398	arg	arg	NOUN
ecletica-1329	147	399	844	844	NUM
ecletica-1329	147	400	,	,	PUNCT
ecletica-1329	147	401	cys800	cys800	PROPN
ecletica-1329	147	402	,	,	PUNCT
ecletica-1329	147	403	ser720	ser720	PROPN
ecletica-1329	147	404	,	,	PUNCT
ecletica-1329	147	405	gly724	gly724	PROPN
ecletica-1329	147	406	,	,	PUNCT
ecletica-1329	147	407	asp840	asp840	PROPN
ecletica-1329	147	408	,	,	PUNCT
ecletica-1329	147	409	leu861	leu861	PROPN
ecletica-1329	147	410	,	,	PUNCT
ecletica-1329	147	411	phe723	phe723	PROPN
ecletica-1329	147	412	,	,	PUNCT
ecletica-1329	147	413	asn845	asn845	PROPN
ecletica-1329	147	414	,	,	PUNCT
ecletica-1329	147	415	asp858	asp858	PROPN
ecletica-1329	147	416	,	,	PUNCT
ecletica-1329	147	417	gly719	gly719	PROPN
ecletica-1329	147	418	,	,	PUNCT
ecletica-1329	147	419	leu847	leu847	PROPN
ecletica-1329	147	420	–	–	PUNCT
ecletica-1329	147	421	8.4	8.4	NUM
ecletica-1329	147	422	c12	c12	PROPN
ecletica-1329	147	423	lys745	lys745	PROPN
ecletica-1329	147	424	cys800	cys800	PROPN
ecletica-1329	147	425	,	,	PUNCT
ecletica-1329	147	426	asn845	asn845	PROPN
ecletica-1329	147	427	,	,	PUNCT
ecletica-1329	147	428	asp858	asp858	PROPN
ecletica-1329	147	429	,	,	PUNCT
ecletica-1329	147	430	gly724	gly724	PROPN
ecletica-1329	147	431	,	,	PUNCT
ecletica-1329	147	432	glu758	glu758	PROPN
ecletica-1329	147	433	,	,	PUNCT
ecletica-1329	147	434	leu747	leu747	PROPN
ecletica-1329	147	435	,	,	PUNCT
ecletica-1329	147	436	leu861	leu861	PROPN
ecletica-1329	147	437	,	,	PUNCT
ecletica-1329	147	438	gly860	gly860	NOUN
ecletica-1329	147	439	,	,	PUNCT
ecletica-1329	147	440	lys878	lys878	PROPN
ecletica-1329	147	441	,	,	PUNCT
ecletica-1329	147	442	pro880	pro880	ADJ
ecletica-1329	147	443	,	,	PUNCT
ecletica-1329	147	444	val879	val879	ADJ
ecletica-1329	147	445	,	,	PUNCT
ecletica-1329	147	446	phe723	phe723	PROPN
ecletica-1329	147	447	,	,	PUNCT
ecletica-1329	147	448	asp840	asp840	PROPN
ecletica-1329	147	449	,	,	PUNCT
ecletica-1329	147	450	arg844	arg844	PROPN
ecletica-1329	147	451	,	,	PUNCT
ecletica-1329	147	452	val726	val726	PROPN
ecletica-1329	147	453	,	,	PUNCT
ecletica-1329	147	454	thr857	thr857	PROPN
ecletica-1329	147	455	,	,	PUNCT
ecletica-1329	147	456	leu847	leu847	PROPN
ecletica-1329	147	457	–	–	PUNCT
ecletica-1329	147	458	9.5	9.5	NUM
ecletica-1329	147	459	c13	c13	PROPN
ecletica-1329	147	460	arg844	arg844	PROPN
ecletica-1329	147	461	thr793	thr793	PROPN
ecletica-1329	147	462	,	,	PUNCT
ecletica-1329	147	463	thr857	thr857	PROPN
ecletica-1329	147	464	,	,	PUNCT
ecletica-1329	147	465	lys745	lys745	ADV
ecletica-1329	147	466	,	,	PUNCT
ecletica-1329	147	467	glu762	glu762	PROPN
ecletica-1329	147	468	,	,	PUNCT
ecletica-1329	147	469	cys800	cys800	PROPN
ecletica-1329	147	470	,	,	PUNCT
ecletica-1329	147	471	gly724	gly724	PROPN
ecletica-1329	147	472	,	,	PUNCT
ecletica-1329	147	473	asp840	asp840	NOUN
ecletica-1329	147	474	,	,	PUNCT
ecletica-1329	147	475	leu861	leu861	PROPN
ecletica-1329	147	476	,	,	PUNCT
ecletica-1329	147	477	asp858	asp858	PROPN
ecletica-1329	147	478	,	,	PUNCT
ecletica-1329	147	479	phe723	phe723	PROPN
ecletica-1329	147	480	,	,	PUNCT
ecletica-1329	147	481	asn845	asn845	PROPN
ecletica-1329	147	482	,	,	PUNCT
ecletica-1329	147	483	gly721	gly721	PROPN
ecletica-1329	147	484	,	,	PUNCT
ecletica-1329	147	485	ser720	ser720	PROPN
ecletica-1329	147	486	,	,	PUNCT
ecletica-1329	147	487	gy719	gy719	PROPN
ecletica-1329	147	488	,	,	PUNCT
ecletica-1329	147	489	gly799	gly799	PROPN
ecletica-1329	147	490	,	,	PUNCT
ecletica-1329	147	491	ala743	ala743	PROPN
ecletica-1329	147	492	,	,	PUNCT
ecletica-1329	147	493	leu718	leu718	PROPN
ecletica-1329	147	494	,	,	PUNCT
ecletica-1329	147	495	leu847	leu847	PROPN
ecletica-1329	147	496	,	,	PUNCT
ecletica-1329	147	497	leu795	leu795	PROPN
ecletica-1329	147	498	,	,	PUNCT
ecletica-1329	147	499	val726	val726	PROPN
ecletica-1329	147	500	–	–	PUNCT
ecletica-1329	147	501	9.4	9.4	NUM
ecletica-1329	147	502	c14	c14	NOUN
ecletica-1329	147	503	lys745	lys745	ADV
ecletica-1329	147	504	,	,	PUNCT
ecletica-1329	147	505	arg844	arg844	PROPN
ecletica-1329	147	506	thr857	thr857	PROPN
ecletica-1329	147	507	,	,	PUNCT
ecletica-1329	147	508	thr793	thr793	PROPN
ecletica-1329	147	509	,	,	PUNCT
ecletica-1329	147	510	asp858	asp858	PROPN
ecletica-1329	147	511	,	,	PUNCT
ecletica-1329	147	512	asn845	asn845	PROPN
ecletica-1329	147	513	,	,	PUNCT
ecletica-1329	147	514	gly724	gly724	PROPN
ecletica-1329	147	515	,	,	PUNCT
ecletica-1329	147	516	gly860	gly860	NOUN
ecletica-1329	147	517	,	,	PUNCT
ecletica-1329	147	518	ile759	ile759	ADJ
ecletica-1329	147	519	,	,	PUNCT
ecletica-1329	147	520	glu758	glu758	PROPN
ecletica-1329	147	521	,	,	PUNCT
ecletica-1329	147	522	lys878	lys878	PROPN
ecletica-1329	147	523	,	,	PUNCT
ecletica-1329	147	524	leu861	leu861	PROPN
ecletica-1329	147	525	,	,	PUNCT
ecletica-1329	147	526	val879	val879	VERB
ecletica-1329	147	527	,	,	PUNCT
ecletica-1329	147	528	pro880	pro880	PROPN
ecletica-1329	147	529	,	,	PUNCT
ecletica-1329	147	530	asp840	asp840	NOUN
ecletica-1329	147	531	,	,	PUNCT
ecletica-1329	147	532	phe723	phe723	PROPN
ecletica-1329	147	533	,	,	PUNCT
ecletica-1329	147	534	gly719	gly719	PROPN
ecletica-1329	147	535	,	,	PUNCT
ecletica-1329	147	536	cys800	cys800	PROPN
ecletica-1329	147	537	,	,	PUNCT
ecletica-1329	147	538	val726	val726	PROPN
ecletica-1329	147	539	,	,	PUNCT
ecletica-1329	147	540	ala743	ala743	PROPN
ecletica-1329	147	541	,	,	PUNCT
ecletica-1329	147	542	leu847	leu847	ADJ
ecletica-1329	147	543	thr857	thr857	PROPN
ecletica-1329	147	544	–	–	PUNCT
ecletica-1329	147	545	10.1	10.1	NUM
ecletica-1329	147	546	figure	figure	NOUN
ecletica-1329	147	547	3	3	NUM
ecletica-1329	147	548	.	.	PUNCT
ecletica-1329	148	1	(	(	PUNCT
ecletica-1329	148	2	a	a	X
ecletica-1329	148	3	)	)	PUNCT
ecletica-1329	148	4	3d	3d	NOUN
ecletica-1329	148	5	and	and	CCONJ
ecletica-1329	148	6	(	(	PUNCT
ecletica-1329	148	7	b	b	NOUN
ecletica-1329	148	8	)	)	PUNCT
ecletica-1329	148	9	2d	2d	NOUN
ecletica-1329	148	10	views	view	NOUN
ecletica-1329	148	11	of	of	ADP
ecletica-1329	148	12	the	the	DET
ecletica-1329	148	13	molecular	molecular	ADJ
ecletica-1329	148	14	interactions	interaction	NOUN
ecletica-1329	148	15	of	of	ADP
ecletica-1329	148	16	amino	amino	NOUN
ecletica-1329	148	17	acid	acid	NOUN
ecletica-1329	148	18	residues	residue	NOUN
ecletica-1329	148	19	of	of	ADP
ecletica-1329	148	20	receptor	receptor	NOUN
ecletica-1329	148	21	4lrm	4lrm	NOUN
ecletica-1329	148	22	with	with	ADP
ecletica-1329	148	23	compound	compound	NOUN
ecletica-1329	148	24	14	14	NUM
ecletica-1329	148	25	.	.	PUNCT
ecletica-1329	149	1	https://revista.iq.unesp.br/index.php/ecletica	https://revista.iq.unesp.br/index.php/ecletica	PROPN
ecletica-1329	149	2	https://doi.org/10.26850/1678-4618eqj.v48.1.2023.p55-71	https://doi.org/10.26850/1678-4618eqj.v48.1.2023.p55-71	PROPN
ecletica-1329	149	3	original	original	ADJ
ecletica-1329	149	4	article	article	NOUN
ecletica-1329	149	5	revista.iq.unesp.br	revista.iq.unesp.br	PROPN
ecletica-1329	149	6	65	65	NUM
ecletica-1329	149	7	eclética	eclética	PROPN
ecletica-1329	149	8	química	química	PROPN
ecletica-1329	149	9	,	,	PUNCT
ecletica-1329	149	10	vol	vol	NOUN
ecletica-1329	149	11	.	.	PROPN
ecletica-1329	149	12	48	48	NUM
ecletica-1329	149	13	,	,	PUNCT
ecletica-1329	149	14	n.	n.	NOUN
ecletica-1329	149	15	1	1	NUM
ecletica-1329	149	16	,	,	PUNCT
ecletica-1329	149	17	2023	2023	NUM
ecletica-1329	149	18	,	,	PUNCT
ecletica-1329	149	19	55	55	NUM
ecletica-1329	149	20	-	-	SYM
ecletica-1329	149	21	71	71	NUM
ecletica-1329	149	22	issn	issn	NOUN
ecletica-1329	149	23	:	:	PUNCT
ecletica-1329	149	24	1678	1678	NUM
ecletica-1329	149	25	-	-	SYM
ecletica-1329	149	26	4618	4618	NUM
ecletica-1329	149	27	doi	doi	NOUN
ecletica-1329	149	28	:	:	PUNCT
ecletica-1329	149	29	10.26850/1678	10.26850/1678	NUM
ecletica-1329	149	30	-	-	PUNCT
ecletica-1329	149	31	4618eqj.v48.1.2023.p55	4618eqj.v48.1.2023.p55	NUM
ecletica-1329	149	32	-	-	PUNCT
ecletica-1329	149	33	71	71	NUM
ecletica-1329	149	34	3.3	3.3	NUM
ecletica-1329	149	35	admet	admet	NOUN
ecletica-1329	149	36	profiling	profiling	NOUN
ecletica-1329	149	37	regardless	regardless	ADV
ecletica-1329	149	38	of	of	ADP
ecletica-1329	149	39	the	the	DET
ecletica-1329	149	40	compounds	compound	NOUN
ecletica-1329	149	41	inhibitory	inhibitory	ADJ
ecletica-1329	149	42	capability	capability	NOUN
ecletica-1329	149	43	against	against	ADP
ecletica-1329	149	44	target	target	NOUN
ecletica-1329	149	45	proteins	protein	NOUN
ecletica-1329	149	46	,	,	PUNCT
ecletica-1329	149	47	the	the	DET
ecletica-1329	149	48	admet	admet	NOUN
ecletica-1329	149	49	properties	property	NOUN
ecletica-1329	149	50	of	of	ADP
ecletica-1329	149	51	the	the	DET
ecletica-1329	149	52	compounds	compound	NOUN
ecletica-1329	149	53	are	be	AUX
ecletica-1329	149	54	a	a	DET
ecletica-1329	149	55	critical	critical	ADJ
ecletica-1329	149	56	element	element	NOUN
ecletica-1329	149	57	in	in	ADP
ecletica-1329	149	58	determining	determine	VERB
ecletica-1329	149	59	their	their	PRON
ecletica-1329	149	60	pharmacological	pharmacological	ADJ
ecletica-1329	149	61	activities	activity	NOUN
ecletica-1329	149	62	such	such	ADJ
ecletica-1329	149	63	as	as	ADP
ecletica-1329	149	64	drug	drug	NOUN
ecletica-1329	149	65	-	-	PUNCT
ecletica-1329	149	66	likeness	likeness	NOUN
ecletica-1329	149	67	,	,	PUNCT
ecletica-1329	149	68	lipophilicity	lipophilicity	NOUN
ecletica-1329	149	69	,	,	PUNCT
ecletica-1329	149	70	pharmacokinetics	pharmacokinetic	NOUN
ecletica-1329	149	71	,	,	PUNCT
ecletica-1329	149	72	and	and	CCONJ
ecletica-1329	149	73	toxicity	toxicity	NOUN
ecletica-1329	149	74	profile	profile	NOUN
ecletica-1329	149	75	when	when	SCONJ
ecletica-1329	149	76	used	use	VERB
ecletica-1329	149	77	as	as	ADP
ecletica-1329	149	78	drug	drug	NOUN
ecletica-1329	149	79	.	.	PUNCT
ecletica-1329	150	1	in	in	ADP
ecletica-1329	150	2	silico	silico	NOUN
ecletica-1329	150	3	admet	admet	NOUN
ecletica-1329	150	4	prediction	prediction	NOUN
ecletica-1329	150	5	is	be	AUX
ecletica-1329	150	6	a	a	DET
ecletica-1329	150	7	quick	quick	ADJ
ecletica-1329	150	8	and	and	CCONJ
ecletica-1329	150	9	low	low	ADJ
ecletica-1329	150	10	-	-	PUNCT
ecletica-1329	150	11	cost	cost	NOUN
ecletica-1329	150	12	method	method	NOUN
ecletica-1329	150	13	of	of	ADP
ecletica-1329	150	14	determining	determine	VERB
ecletica-1329	150	15	whether	whether	SCONJ
ecletica-1329	150	16	a	a	DET
ecletica-1329	150	17	molecule	molecule	NOUN
ecletica-1329	150	18	will	will	AUX
ecletica-1329	150	19	be	be	AUX
ecletica-1329	150	20	well	well	ADV
ecletica-1329	150	21	distributed	distribute	VERB
ecletica-1329	150	22	to	to	ADP
ecletica-1329	150	23	its	its	PRON
ecletica-1329	150	24	intended	intended	ADJ
ecletica-1329	150	25	site	site	NOUN
ecletica-1329	150	26	of	of	ADP
ecletica-1329	150	27	action	action	NOUN
ecletica-1329	150	28	,	,	PUNCT
ecletica-1329	150	29	metabolized	metabolize	VERB
ecletica-1329	150	30	efficiently	efficiently	ADV
ecletica-1329	150	31	,	,	PUNCT
ecletica-1329	150	32	and	and	CCONJ
ecletica-1329	150	33	quickly	quickly	ADV
ecletica-1329	150	34	removed	remove	VERB
ecletica-1329	150	35	from	from	ADP
ecletica-1329	150	36	the	the	DET
ecletica-1329	150	37	body	body	NOUN
ecletica-1329	150	38	without	without	ADP
ecletica-1329	150	39	causing	cause	VERB
ecletica-1329	150	40	hazardous	hazardous	ADJ
ecletica-1329	150	41	side	side	NOUN
ecletica-1329	150	42	effects	effect	NOUN
ecletica-1329	150	43	(	(	PUNCT
ecletica-1329	150	44	ntie	ntie	NOUN
ecletica-1329	150	45	-	-	PUNCT
ecletica-1329	150	46	kang	kang	PROPN
ecletica-1329	150	47	,	,	PUNCT
ecletica-1329	150	48	2013	2013	NUM
ecletica-1329	150	49	)	)	PUNCT
ecletica-1329	150	50	.	.	PUNCT
ecletica-1329	151	1	the	the	DET
ecletica-1329	151	2	prediction	prediction	NOUN
ecletica-1329	151	3	output	output	NOUN
ecletica-1329	151	4	for	for	ADP
ecletica-1329	151	5	drug	drug	NOUN
ecletica-1329	151	6	likeness	likeness	NOUN
ecletica-1329	151	7	,	,	PUNCT
ecletica-1329	151	8	lipophilicity	lipophilicity	NOUN
ecletica-1329	151	9	pharmacokinetics	pharmacokinetic	NOUN
ecletica-1329	151	10	,	,	PUNCT
ecletica-1329	151	11	and	and	CCONJ
ecletica-1329	151	12	toxicity	toxicity	NOUN
ecletica-1329	151	13	profiles	profile	NOUN
ecletica-1329	151	14	of	of	ADP
ecletica-1329	151	15	test	test	NOUN
ecletica-1329	151	16	molecules	molecule	NOUN
ecletica-1329	151	17	are	be	AUX
ecletica-1329	151	18	displayed	display	VERB
ecletica-1329	151	19	on	on	ADP
ecletica-1329	151	20	tables	table	NOUN
ecletica-1329	151	21	9–11	9–11	NOUN
ecletica-1329	151	22	respectively	respectively	ADV
ecletica-1329	151	23	.	.	PUNCT
ecletica-1329	152	1	drug	drug	NOUN
ecletica-1329	152	2	-	-	PUNCT
ecletica-1329	152	3	likeness	likeness	NOUN
ecletica-1329	152	4	analysis	analysis	NOUN
ecletica-1329	152	5	is	be	AUX
ecletica-1329	152	6	a	a	DET
ecletica-1329	152	7	qualitative	qualitative	ADJ
ecletica-1329	152	8	evaluation	evaluation	NOUN
ecletica-1329	152	9	of	of	ADP
ecletica-1329	152	10	oral	oral	ADJ
ecletica-1329	152	11	bioavailability	bioavailability	NOUN
ecletica-1329	152	12	based	base	VERB
ecletica-1329	152	13	on	on	ADP
ecletica-1329	152	14	structural	structural	ADJ
ecletica-1329	152	15	or	or	CCONJ
ecletica-1329	152	16	physicochemical	physicochemical	ADJ
ecletica-1329	152	17	examination	examination	NOUN
ecletica-1329	152	18	of	of	ADP
ecletica-1329	152	19	molecules	molecule	NOUN
ecletica-1329	152	20	.	.	PUNCT
ecletica-1329	153	1	in	in	ADP
ecletica-1329	153	2	this	this	DET
ecletica-1329	153	3	study	study	NOUN
ecletica-1329	153	4	the	the	DET
ecletica-1329	153	5	rule	rule	NOUN
ecletica-1329	153	6	base	base	NOUN
ecletica-1329	153	7	filters	filter	NOUN
ecletica-1329	153	8	which	which	PRON
ecletica-1329	153	9	include	include	VERB
ecletica-1329	153	10	lipinski	lipinski	PROPN
ecletica-1329	153	11	’s	’s	PROPN
ecletica-1329	153	12	et	et	PROPN
ecletica-1329	153	13	al	al	PROPN
ecletica-1329	153	14	.	.	PROPN
ecletica-1329	154	1	(	(	PUNCT
ecletica-1329	154	2	2013	2013	NUM
ecletica-1329	154	3	)	)	PUNCT
ecletica-1329	154	4	,	,	PUNCT
ecletica-1329	154	5	veber	veber	PROPN
ecletica-1329	154	6	et	et	PROPN
ecletica-1329	154	7	al	al	PROPN
ecletica-1329	154	8	.	.	PROPN
ecletica-1329	155	1	(	(	PUNCT
ecletica-1329	155	2	2002	2002	NUM
ecletica-1329	155	3	)	)	PUNCT
ecletica-1329	155	4	,	,	PUNCT
ecletica-1329	155	5	and	and	CCONJ
ecletica-1329	155	6	muegge	muegge	PROPN
ecletica-1329	155	7	and	and	CCONJ
ecletica-1329	155	8	ghose	ghose	PROPN
ecletica-1329	155	9	(	(	PUNCT
ecletica-1329	155	10	2001	2001	NUM
ecletica-1329	155	11	)	)	PUNCT
ecletica-1329	155	12	rules	rule	NOUN
ecletica-1329	155	13	were	be	AUX
ecletica-1329	155	14	employed	employ	VERB
ecletica-1329	155	15	to	to	PART
ecletica-1329	155	16	determine	determine	VERB
ecletica-1329	155	17	if	if	SCONJ
ecletica-1329	155	18	a	a	DET
ecletica-1329	155	19	molecule	molecule	NOUN
ecletica-1329	155	20	is	be	AUX
ecletica-1329	155	21	impermeable	impermeable	ADJ
ecletica-1329	155	22	or	or	CCONJ
ecletica-1329	155	23	badly	badly	ADV
ecletica-1329	155	24	absorbed	absorb	VERB
ecletica-1329	155	25	.	.	PUNCT
ecletica-1329	156	1	if	if	SCONJ
ecletica-1329	156	2	a	a	DET
ecletica-1329	156	3	molecule	molecule	NOUN
ecletica-1329	156	4	does	do	AUX
ecletica-1329	156	5	not	not	PART
ecletica-1329	156	6	break	break	VERB
ecletica-1329	156	7	more	more	ADJ
ecletica-1329	156	8	than	than	ADP
ecletica-1329	156	9	two	two	NUM
ecletica-1329	156	10	rules	rule	NOUN
ecletica-1329	156	11	,	,	PUNCT
ecletica-1329	156	12	it	it	PRON
ecletica-1329	156	13	is	be	AUX
ecletica-1329	156	14	deemed	deem	VERB
ecletica-1329	156	15	orally	orally	ADV
ecletica-1329	156	16	bioavailable	bioavailable	ADJ
ecletica-1329	156	17	.	.	PUNCT
ecletica-1329	157	1	as	as	SCONJ
ecletica-1329	157	2	indicated	indicate	VERB
ecletica-1329	157	3	on	on	ADP
ecletica-1329	157	4	table	table	NOUN
ecletica-1329	157	5	8	8	NUM
ecletica-1329	157	6	,	,	PUNCT
ecletica-1329	157	7	the	the	DET
ecletica-1329	157	8	molecular	molecular	ADJ
ecletica-1329	157	9	weights	weight	NOUN
ecletica-1329	157	10	of	of	ADP
ecletica-1329	157	11	the	the	DET
ecletica-1329	157	12	compounds	compound	NOUN
ecletica-1329	157	13	range	range	VERB
ecletica-1329	157	14	from	from	ADP
ecletica-1329	157	15	130	130	NUM
ecletica-1329	157	16	(	(	PUNCT
ecletica-1329	157	17	5	5	NUM
ecletica-1329	157	18	-	-	PUNCT
ecletica-1329	157	19	fu	fu	NOUN
ecletica-1329	157	20	)	)	PUNCT
ecletica-1329	157	21	to	to	ADP
ecletica-1329	157	22	590	590	NUM
ecletica-1329	157	23	g	g	NOUN
ecletica-1329	157	24	mol–1	mol–1	NOUN
ecletica-1329	157	25	(	(	PUNCT
ecletica-1329	157	26	c14	c14	NOUN
ecletica-1329	157	27	)	)	PUNCT
ecletica-1329	157	28	.	.	PUNCT
ecletica-1329	158	1	the	the	DET
ecletica-1329	158	2	hba	hba	NOUN
ecletica-1329	158	3	ranged	range	VERB
ecletica-1329	158	4	from	from	ADP
ecletica-1329	158	5	3	3	NUM
ecletica-1329	158	6	to	to	PART
ecletica-1329	158	7	8	8	NUM
ecletica-1329	158	8	and	and	CCONJ
ecletica-1329	158	9	hbds	hbds	NOUN
ecletica-1329	158	10	ranged	range	VERB
ecletica-1329	158	11	from	from	ADP
ecletica-1329	158	12	0	0	NUM
ecletica-1329	158	13	to	to	ADP
ecletica-1329	158	14	2	2	NUM
ecletica-1329	158	15	;	;	PUNCT
ecletica-1329	158	16	number	number	NOUN
ecletica-1329	158	17	of	of	ADP
ecletica-1329	158	18	rotatable	rotatable	ADJ
ecletica-1329	158	19	bonds	bond	NOUN
ecletica-1329	158	20	are	be	AUX
ecletica-1329	158	21	between	between	ADP
ecletica-1329	158	22	0	0	NUM
ecletica-1329	158	23	(	(	PUNCT
ecletica-1329	158	24	5	5	NUM
ecletica-1329	158	25	-	-	PUNCT
ecletica-1329	158	26	fu	fu	NOUN
ecletica-1329	158	27	)	)	PUNCT
ecletica-1329	158	28	to	to	ADP
ecletica-1329	158	29	9	9	NUM
ecletica-1329	158	30	(	(	PUNCT
ecletica-1329	158	31	c11	c11	NOUN
ecletica-1329	158	32	)	)	PUNCT
ecletica-1329	158	33	.	.	PUNCT
ecletica-1329	159	1	the	the	DET
ecletica-1329	159	2	tpsa	tpsa	NOUN
ecletica-1329	159	3	are	be	AUX
ecletica-1329	159	4	between	between	ADP
ecletica-1329	159	5	55.14	55.14	NUM
ecletica-1329	159	6	(	(	PUNCT
ecletica-1329	159	7	5	5	NUM
ecletica-1329	159	8	-	-	PUNCT
ecletica-1329	159	9	fu	fu	NOUN
ecletica-1329	159	10	)	)	PUNCT
ecletica-1329	159	11	and	and	CCONJ
ecletica-1329	159	12	134.93	134.93	NUM
ecletica-1329	159	13	(	(	PUNCT
ecletica-1329	159	14	c13	c13	NOUN
ecletica-1329	159	15	and	and	CCONJ
ecletica-1329	159	16	c14	c14	PROPN
ecletica-1329	159	17	)	)	PUNCT
ecletica-1329	159	18	.	.	PUNCT
ecletica-1329	160	1	mr	mr	PROPN
ecletica-1329	160	2	ranged	range	VERB
ecletica-1329	160	3	from	from	ADP
ecletica-1329	160	4	27.64	27.64	NUM
ecletica-1329	160	5	(	(	PUNCT
ecletica-1329	160	6	5	5	NUM
ecletica-1329	160	7	-	-	PUNCT
ecletica-1329	160	8	fu	fu	NOUN
ecletica-1329	160	9	)	)	PUNCT
ecletica-1329	160	10	to	to	ADP
ecletica-1329	160	11	150.11	150.11	NUM
ecletica-1329	160	12	(	(	PUNCT
ecletica-1329	160	13	c14	c14	NOUN
ecletica-1329	160	14	)	)	PUNCT
ecletica-1329	160	15	.	.	PUNCT
ecletica-1329	161	1	the	the	PRON
ecletica-1329	161	2	less	less	ADJ
ecletica-1329	161	3	the	the	DET
ecletica-1329	161	4	drug	drug	NOUN
ecletica-1329	161	5	candidate	candidate	NOUN
ecletica-1329	161	6	can	can	AUX
ecletica-1329	161	7	infiltrate	infiltrate	VERB
ecletica-1329	161	8	,	,	PUNCT
ecletica-1329	161	9	the	the	PRON
ecletica-1329	161	10	higher	high	ADJ
ecletica-1329	161	11	the	the	DET
ecletica-1329	161	12	tpsa	tpsa	NOUN
ecletica-1329	161	13	and	and	CCONJ
ecletica-1329	161	14	molecular	molecular	ADJ
ecletica-1329	161	15	weight	weight	NOUN
ecletica-1329	161	16	values	value	NOUN
ecletica-1329	161	17	are	be	AUX
ecletica-1329	161	18	,	,	PUNCT
ecletica-1329	161	19	and	and	CCONJ
ecletica-1329	161	20	vice	vice	ADV
ecletica-1329	161	21	versa	versa	ADV
ecletica-1329	161	22	.	.	PUNCT
ecletica-1329	162	1	a	a	DET
ecletica-1329	162	2	target	target	NOUN
ecletica-1329	162	3	molecule	molecule	NOUN
ecletica-1329	162	4	’s	’s	PART
ecletica-1329	162	5	synthetic	synthetic	ADJ
ecletica-1329	162	6	accessibility	accessibility	NOUN
ecletica-1329	162	7	(	(	PUNCT
ecletica-1329	162	8	sa	sa	NOUN
ecletica-1329	162	9	)	)	PUNCT
ecletica-1329	162	10	score	score	NOUN
ecletica-1329	162	11	is	be	AUX
ecletica-1329	162	12	used	use	VERB
ecletica-1329	162	13	to	to	PART
ecletica-1329	162	14	evaluate	evaluate	VERB
ecletica-1329	162	15	it	it	PRON
ecletica-1329	162	16	before	before	SCONJ
ecletica-1329	162	17	it	it	PRON
ecletica-1329	162	18	is	be	AUX
ecletica-1329	162	19	synthesized	synthesize	VERB
ecletica-1329	162	20	.	.	PUNCT
ecletica-1329	163	1	it	it	PRON
ecletica-1329	163	2	is	be	AUX
ecletica-1329	163	3	a	a	DET
ecletica-1329	163	4	parameter	parameter	NOUN
ecletica-1329	163	5	used	use	VERB
ecletica-1329	163	6	to	to	PART
ecletica-1329	163	7	rate	rate	VERB
ecletica-1329	163	8	the	the	DET
ecletica-1329	163	9	ease	ease	NOUN
ecletica-1329	163	10	or	or	CCONJ
ecletica-1329	163	11	difficulty	difficulty	NOUN
ecletica-1329	163	12	of	of	ADP
ecletica-1329	163	13	synthesizing	synthesize	VERB
ecletica-1329	163	14	a	a	DET
ecletica-1329	163	15	compound	compound	NOUN
ecletica-1329	163	16	.	.	PUNCT
ecletica-1329	164	1	the	the	DET
ecletica-1329	164	2	sa	sa	PROPN
ecletica-1329	164	3	score	score	NOUN
ecletica-1329	164	4	runs	run	VERB
ecletica-1329	164	5	from	from	ADP
ecletica-1329	164	6	1	1	NUM
ecletica-1329	164	7	(	(	PUNCT
ecletica-1329	164	8	very	very	ADV
ecletica-1329	164	9	easy	easy	ADJ
ecletica-1329	164	10	)	)	PUNCT
ecletica-1329	164	11	to	to	ADP
ecletica-1329	164	12	10	10	NUM
ecletica-1329	164	13	(	(	PUNCT
ecletica-1329	164	14	very	very	ADV
ecletica-1329	164	15	tough	tough	ADJ
ecletica-1329	164	16	)	)	PUNCT
ecletica-1329	164	17	(	(	PUNCT
ecletica-1329	164	18	swierczewska	swierczewska	NOUN
ecletica-1329	164	19	et	et	PROPN
ecletica-1329	164	20	al	al	PROPN
ecletica-1329	164	21	.	.	PROPN
ecletica-1329	164	22	,	,	PUNCT
ecletica-1329	164	23	2015	2015	NUM
ecletica-1329	164	24	)	)	PUNCT
ecletica-1329	164	25	.	.	PUNCT
ecletica-1329	165	1	the	the	DET
ecletica-1329	165	2	studied	study	VERB
ecletica-1329	165	3	compounds	compound	NOUN
ecletica-1329	165	4	possess	possess	VERB
ecletica-1329	165	5	good	good	ADJ
ecletica-1329	165	6	sa	sa	PROPN
ecletica-1329	165	7	,	,	PUNCT
ecletica-1329	165	8	with	with	ADP
ecletica-1329	165	9	sa	sa	PROPN
ecletica-1329	165	10	scores	score	NOUN
ecletica-1329	165	11	ranging	range	VERB
ecletica-1329	165	12	from	from	ADP
ecletica-1329	165	13	1.52	1.52	NUM
ecletica-1329	165	14	to	to	ADP
ecletica-1329	165	15	4.13	4.13	NUM
ecletica-1329	165	16	as	as	SCONJ
ecletica-1329	165	17	shown	show	VERB
ecletica-1329	165	18	in	in	ADP
ecletica-1329	165	19	table	table	NOUN
ecletica-1329	165	20	8	8	NUM
ecletica-1329	165	21	.	.	PUNCT
ecletica-1329	165	22	table	table	NOUN
ecletica-1329	165	23	8	8	NUM
ecletica-1329	165	24	.	.	PUNCT
ecletica-1329	165	25	drug	drug	NOUN
ecletica-1329	165	26	-	-	PUNCT
ecletica-1329	165	27	likeness	likeness	NOUN
ecletica-1329	165	28	prediction	prediction	NOUN
ecletica-1329	165	29	output	output	NOUN
ecletica-1329	165	30	of	of	ADP
ecletica-1329	165	31	test	test	NOUN
ecletica-1329	165	32	compounds	compound	NOUN
ecletica-1329	165	33	.	.	PUNCT
ecletica-1329	166	1	sample	sample	NOUN
ecletica-1329	166	2	code	code	NOUN
ecletica-1329	166	3	chemical	chemical	NOUN
ecletica-1329	166	4	formula	formula	NOUN
ecletica-1329	166	5	mw	mw	X
ecletica-1329	166	6	(	(	PUNCT
ecletica-1329	166	7	g	g	NOUN
ecletica-1329	166	8	mol–1	mol–1	NOUN
ecletica-1329	166	9	)	)	PUNCT
ecletica-1329	166	10	rotatable	rotatable	ADJ
ecletica-1329	166	11	bond	bond	NOUN
ecletica-1329	166	12	hba	hba	PROPN
ecletica-1329	166	13	hbd	hbd	PROPN
ecletica-1329	166	14	tpsa	tpsa	PROPN
ecletica-1329	166	15	mr	mr	PROPN
ecletica-1329	166	16	sa	sa	PROPN
ecletica-1329	166	17	c1	c1	PROPN
ecletica-1329	166	18	c18h17cln2o2	c18h17cln2o2	VERB
ecletica-1329	166	19	328.79	328.79	NUM
ecletica-1329	166	20	3	3	NUM
ecletica-1329	166	21	4	4	NUM
ecletica-1329	166	22	0	0	NUM
ecletica-1329	166	23	55.14	55.14	NUM
ecletica-1329	166	24	89.81	89.81	NUM
ecletica-1329	166	25	2.93	2.93	NUM
ecletica-1329	166	26	c2	c2	PROPN
ecletica-1329	166	27	c18h20n4o2	c18h20n4o2	PROPN
ecletica-1329	167	1	324.38	324.38	NUM
ecletica-1329	167	2	3	3	NUM
ecletica-1329	167	3	4	4	NUM
ecletica-1329	167	4	2	2	NUM
ecletica-1329	167	5	86.05	86.05	NUM
ecletica-1329	167	6	94.15	94.15	NUM
ecletica-1329	167	7	3.11	3.11	NUM
ecletica-1329	167	8	c3	c3	NOUN
ecletica-1329	167	9	c27h29n5o2	c27h29n5o2	PROPN
ecletica-1329	167	10	455.55	455.55	NUM
ecletica-1329	167	11	6	6	NUM
ecletica-1329	167	12	5	5	NUM
ecletica-1329	167	13	1	1	NUM
ecletica-1329	167	14	75.63	75.63	NUM
ecletica-1329	167	15	137.64	137.64	NUM
ecletica-1329	167	16	4.04	4.04	NUM
ecletica-1329	167	17	c4	c4	NOUN
ecletica-1329	167	18	c25h22cl2n4o2	c25h22cl2n4o2	VERB
ecletica-1329	167	19	481.37	481.37	NUM
ecletica-1329	167	20	5	5	NUM
ecletica-1329	167	21	5	5	NUM
ecletica-1329	167	22	1	1	NUM
ecletica-1329	167	23	72.39	72.39	NUM
ecletica-1329	167	24	133.46	133.46	NUM
ecletica-1329	167	25	3.82	3.82	NUM
ecletica-1329	167	26	c5	c5	PROPN
ecletica-1329	167	27	c26h26n4o2	c26h26n4o2	VERB
ecletica-1329	167	28	426.51	426.51	NUM
ecletica-1329	167	29	5	5	NUM
ecletica-1329	167	30	5	5	NUM
ecletica-1329	167	31	1	1	NUM
ecletica-1329	167	32	72.39	72.39	NUM
ecletica-1329	167	33	128.4	128.4	NUM
ecletica-1329	167	34	3.89	3.89	NUM
ecletica-1329	167	35	c6	c6	PROPN
ecletica-1329	167	36	c26h23n5o3	c26h23n5o3	PROPN
ecletica-1329	167	37	453.49	453.49	NUM
ecletica-1329	167	38	4	4	NUM
ecletica-1329	167	39	6	6	NUM
ecletica-1329	167	40	2	2	NUM
ecletica-1329	167	41	101.49	101.49	NUM
ecletica-1329	167	42	133.76	133.76	NUM
ecletica-1329	167	43	3.91	3.91	NUM
ecletica-1329	167	44	c7	c7	PROPN
ecletica-1329	167	45	c26h22cln5o3	c26h22cln5o3	PROPN
ecletica-1329	167	46	487.94	487.94	NUM
ecletica-1329	167	47	4	4	NUM
ecletica-1329	167	48	6	6	NUM
ecletica-1329	167	49	2	2	NUM
ecletica-1329	167	50	101.49	101.49	NUM
ecletica-1329	167	51	138.77	138.77	NUM
ecletica-1329	167	52	3.92	3.92	NUM
ecletica-1329	167	53	c8	c8	PROPN
ecletica-1329	167	54	c26h22brn5o3	c26h22brn5o3	PROPN
ecletica-1329	167	55	532.39	532.39	NUM
ecletica-1329	167	56	4	4	NUM
ecletica-1329	167	57	6	6	NUM
ecletica-1329	167	58	2	2	NUM
ecletica-1329	167	59	101.49	101.49	NUM
ecletica-1329	167	60	141.46	141.46	NUM
ecletica-1329	167	61	3.97	3.97	NUM
ecletica-1329	167	62	c9	c9	NOUN
ecletica-1329	167	63	c22h24n2o5	c22h24n2o5	PROPN
ecletica-1329	167	64	396.44	396.44	NUM
ecletica-1329	167	65	8	8	NUM
ecletica-1329	167	66	7	7	NUM
ecletica-1329	167	67	0	0	NUM
ecletica-1329	167	68	90.67	90.67	NUM
ecletica-1329	167	69	107.00	107.00	NUM
ecletica-1329	167	70	3.55	3.55	NUM
ecletica-1329	167	71	c10	c10	VERB
ecletica-1329	167	72	c20h22n4o4	c20h22n4o4	PROPN
ecletica-1329	167	73	382.41	382.41	NUM
ecletica-1329	167	74	7	7	NUM
ecletica-1329	167	75	7	7	NUM
ecletica-1329	167	76	2	2	NUM
ecletica-1329	167	77	119.49	119.49	NUM
ecletica-1329	167	78	101.81	101.81	NUM
ecletica-1329	167	79	3.36	3.36	NUM
ecletica-1329	167	80	c11	c11	NOUN
ecletica-1329	167	81	c28h28n4o4	c28h28n4o4	NOUN
ecletica-1329	168	1	484.55	484.55	NUM
ecletica-1329	168	2	9	9	NUM
ecletica-1329	168	3	7	7	NUM
ecletica-1329	168	4	1	1	NUM
ecletica-1329	168	5	105.83	105.83	NUM
ecletica-1329	168	6	137.05	137.05	NUM
ecletica-1329	168	7	4.02	4.02	NUM
ecletica-1329	168	8	c12	c12	PROPN
ecletica-1329	168	9	c28h25n5o5	c28h25n5o5	PROPN
ecletica-1329	168	10	511.53	511.53	NUM
ecletica-1329	168	11	8	8	NUM
ecletica-1329	168	12	8	8	NUM
ecletica-1329	168	13	2	2	NUM
ecletica-1329	168	14	134.93	134.93	NUM
ecletica-1329	168	15	142.41	142.41	NUM
ecletica-1329	168	16	4.06	4.06	NUM
ecletica-1329	168	17	c13	c13	PROPN
ecletica-1329	168	18	c28h24cln5o5	c28h24cln5o5	NOUN
ecletica-1329	168	19	545.97	545.97	NUM
ecletica-1329	168	20	8	8	NUM
ecletica-1329	168	21	8	8	NUM
ecletica-1329	168	22	2	2	NUM
ecletica-1329	168	23	134.93	134.93	NUM
ecletica-1329	168	24	147.42	147.42	NUM
ecletica-1329	168	25	4.06	4.06	NUM
ecletica-1329	168	26	c14	c14	NOUN
ecletica-1329	168	27	c28h24brn5o5	c28h24brn5o5	NOUN
ecletica-1329	168	28	590.42	590.42	NUM
ecletica-1329	168	29	8	8	NUM
ecletica-1329	168	30	8	8	NUM
ecletica-1329	168	31	2	2	NUM
ecletica-1329	168	32	134.93	134.93	NUM
ecletica-1329	168	33	150.11	150.11	NUM
ecletica-1329	168	34	4.13	4.13	NUM
ecletica-1329	168	35	5	5	NUM
ecletica-1329	168	36	-	-	PUNCT
ecletica-1329	168	37	flu	flu	NOUN
ecletica-1329	168	38	c4h3fn2o2	c4h3fn2o2	NOUN
ecletica-1329	168	39	130.08	130.08	NUM
ecletica-1329	168	40	0	0	NUM
ecletica-1329	168	41	3	3	NUM
ecletica-1329	168	42	2	2	NUM
ecletica-1329	168	43	65.72	65.72	NUM
ecletica-1329	168	44	27.64	27.64	NUM
ecletica-1329	168	45	1.52	1.52	NUM
ecletica-1329	168	46	5	5	NUM
ecletica-1329	168	47	-	-	PUNCT
ecletica-1329	168	48	flu	flu	NOUN
ecletica-1329	168	49	:	:	PUNCT
ecletica-1329	168	50	5	5	NUM
ecletica-1329	168	51	-	-	PUNCT
ecletica-1329	168	52	flurouracil	flurouracil	NOUN
ecletica-1329	168	53	;	;	PUNCT
ecletica-1329	168	54	mw	mw	X
ecletica-1329	168	55	:	:	PUNCT
ecletica-1329	168	56	molecular	molecular	ADJ
ecletica-1329	168	57	weight	weight	NOUN
ecletica-1329	168	58	;	;	PUNCT
ecletica-1329	168	59	mr	mr	PROPN
ecletica-1329	168	60	:	:	PUNCT
ecletica-1329	168	61	molar	molar	ADJ
ecletica-1329	168	62	refractivity	refractivity	NOUN
ecletica-1329	168	63	;	;	PUNCT
ecletica-1329	168	64	hba	hba	NOUN
ecletica-1329	168	65	:	:	PUNCT
ecletica-1329	168	66	hydrogen	hydrogen	NOUN
ecletica-1329	168	67	bond	bond	NOUN
ecletica-1329	168	68	acceptor	acceptor	NOUN
ecletica-1329	168	69	;	;	PUNCT
ecletica-1329	168	70	hbd	hbd	NOUN
ecletica-1329	168	71	:	:	PUNCT
ecletica-1329	168	72	hydrogen	hydrogen	NOUN
ecletica-1329	168	73	bond	bond	NOUN
ecletica-1329	168	74	donor	donor	NOUN
ecletica-1329	168	75	;	;	PUNCT
ecletica-1329	168	76	tpsa	tpsa	NOUN
ecletica-1329	168	77	:	:	PUNCT
ecletica-1329	168	78	topology	topology	NOUN
ecletica-1329	168	79	polar	polar	ADJ
ecletica-1329	168	80	surface	surface	NOUN
ecletica-1329	168	81	area	area	NOUN
ecletica-1329	168	82	;	;	PUNCT
ecletica-1329	168	83	mr	mr	PROPN
ecletica-1329	168	84	:	:	PUNCT
ecletica-1329	168	85	molar	molar	ADJ
ecletica-1329	168	86	refractivity	refractivity	NOUN
ecletica-1329	168	87	;	;	PUNCT
ecletica-1329	168	88	sa	sa	NOUN
ecletica-1329	168	89	:	:	PUNCT
ecletica-1329	168	90	synthetic	synthetic	ADJ
ecletica-1329	168	91	accessibility	accessibility	NOUN
ecletica-1329	168	92	.	.	PUNCT
ecletica-1329	169	1	the	the	DET
ecletica-1329	169	2	partition	partition	NOUN
ecletica-1329	169	3	coefficient	coefficient	NOUN
ecletica-1329	169	4	between	between	ADP
ecletica-1329	169	5	n	n	NOUN
ecletica-1329	169	6	-	-	PUNCT
ecletica-1329	169	7	octanol	octanol	NOUN
ecletica-1329	169	8	and	and	CCONJ
ecletica-1329	169	9	water	water	NOUN
ecletica-1329	169	10	(	(	PUNCT
ecletica-1329	169	11	log	log	VERB
ecletica-1329	169	12	po	po	PROPN
ecletica-1329	169	13	/	/	SYM
ecletica-1329	169	14	w	w	PROPN
ecletica-1329	169	15	)	)	PUNCT
ecletica-1329	169	16	is	be	AUX
ecletica-1329	169	17	the	the	DET
ecletica-1329	169	18	fundamental	fundamental	ADJ
ecletica-1329	169	19	descriptor	descriptor	NOUN
ecletica-1329	169	20	for	for	ADP
ecletica-1329	169	21	lipophilicity	lipophilicity	NOUN
ecletica-1329	169	22	(	(	PUNCT
ecletica-1329	169	23	log	log	VERB
ecletica-1329	169	24	p	p	NOUN
ecletica-1329	169	25	)	)	PUNCT
ecletica-1329	169	26	.	.	PUNCT
ecletica-1329	170	1	the	the	DET
ecletica-1329	170	2	tested	test	VERB
ecletica-1329	170	3	compounds	compound	NOUN
ecletica-1329	170	4	’	'	PUNCT
ecletica-1329	170	5	log	log	NOUN
ecletica-1329	170	6	p	p	NOUN
ecletica-1329	170	7	values	value	NOUN
ecletica-1329	170	8	,	,	PUNCT
ecletica-1329	170	9	water	water	NOUN
ecletica-1329	170	10	solubility	solubility	NOUN
ecletica-1329	170	11	,	,	PUNCT
ecletica-1329	170	12	and	and	CCONJ
ecletica-1329	170	13	bioavailability	bioavailability	NOUN
ecletica-1329	170	14	are	be	AUX
ecletica-1329	170	15	reported	report	VERB
ecletica-1329	170	16	in	in	ADP
ecletica-1329	170	17	table	table	NOUN
ecletica-1329	170	18	9	9	NUM
ecletica-1329	170	19	.	.	PUNCT
ecletica-1329	170	20	lipophilicity	lipophilicity	NOUN
ecletica-1329	170	21	and	and	CCONJ
ecletica-1329	170	22	water	water	NOUN
ecletica-1329	170	23	solubility	solubility	NOUN
ecletica-1329	170	24	are	be	AUX
ecletica-1329	170	25	two	two	NUM
ecletica-1329	170	26	important	important	ADJ
ecletica-1329	170	27	physicochemical	physicochemical	ADJ
ecletica-1329	170	28	qualities	quality	NOUN
ecletica-1329	170	29	that	that	PRON
ecletica-1329	170	30	influence	influence	VERB
ecletica-1329	170	31	a	a	DET
ecletica-1329	170	32	drug	drug	NOUN
ecletica-1329	170	33	’s	’s	PART
ecletica-1329	170	34	behavior	behavior	NOUN
ecletica-1329	170	35	.	.	PUNCT
ecletica-1329	171	1	an	an	DET
ecletica-1329	171	2	orally	orally	ADV
ecletica-1329	171	3	delivered	deliver	VERB
ecletica-1329	171	4	medicine	medicine	NOUN
ecletica-1329	171	5	should	should	AUX
ecletica-1329	171	6	be	be	AUX
ecletica-1329	171	7	lipophilic	lipophilic	ADJ
ecletica-1329	171	8	enough	enough	ADV
ecletica-1329	171	9	to	to	PART
ecletica-1329	171	10	pass	pass	VERB
ecletica-1329	171	11	through	through	ADP
ecletica-1329	171	12	the	the	DET
ecletica-1329	171	13	intestinal	intestinal	ADJ
ecletica-1329	171	14	lining	lining	NOUN
ecletica-1329	171	15	,	,	PUNCT
ecletica-1329	171	16	permeate	permeate	VERB
ecletica-1329	171	17	target	target	NOUN
ecletica-1329	171	18	cell	cell	NOUN
ecletica-1329	171	19	membranes	membrane	NOUN
ecletica-1329	171	20	,	,	PUNCT
ecletica-1329	171	21	and	and	CCONJ
ecletica-1329	171	22	be	be	AUX
ecletica-1329	171	23	hydrophilic	hydrophilic	ADJ
ecletica-1329	171	24	enough	enough	ADV
ecletica-1329	171	25	to	to	PART
ecletica-1329	171	26	move	move	VERB
ecletica-1329	171	27	through	through	ADP
ecletica-1329	171	28	the	the	DET
ecletica-1329	171	29	aqueous	aqueous	ADJ
ecletica-1329	171	30	blood	blood	NOUN
ecletica-1329	171	31	.	.	PUNCT
ecletica-1329	172	1	the	the	PRON
ecletica-1329	172	2	higher	high	ADJ
ecletica-1329	172	3	a	a	DET
ecletica-1329	172	4	compound	compound	NOUN
ecletica-1329	172	5	’s	’s	PART
ecletica-1329	172	6	log	log	NOUN
ecletica-1329	172	7	p	p	NOUN
ecletica-1329	172	8	value	value	NOUN
ecletica-1329	172	9	,	,	PUNCT
ecletica-1329	172	10	the	the	DET
ecletica-1329	172	11	more	more	ADV
ecletica-1329	172	12	lipophilic	lipophilic	ADJ
ecletica-1329	172	13	it	it	PRON
ecletica-1329	172	14	is	be	AUX
ecletica-1329	172	15	and	and	CCONJ
ecletica-1329	172	16	the	the	DET
ecletica-1329	172	17	less	less	ADV
ecletica-1329	172	18	water	water	NOUN
ecletica-1329	172	19	soluble	soluble	ADJ
ecletica-1329	172	20	it	it	PRON
ecletica-1329	172	21	is	be	AUX
ecletica-1329	172	22	(	(	PUNCT
ecletica-1329	172	23	johnson	johnson	PROPN
ecletica-1329	172	24	et	et	PROPN
ecletica-1329	172	25	al	al	PROPN
ecletica-1329	172	26	.	.	PROPN
ecletica-1329	172	27	,	,	PUNCT
ecletica-1329	172	28	2021	2021	NUM
ecletica-1329	172	29	)	)	PUNCT
ecletica-1329	172	30	.	.	PUNCT
ecletica-1329	173	1	the	the	DET
ecletica-1329	173	2	log	log	NOUN
ecletica-1329	173	3	p	p	NOUN
ecletica-1329	173	4	values	value	NOUN
ecletica-1329	173	5	for	for	ADP
ecletica-1329	173	6	the	the	DET
ecletica-1329	173	7	studied	study	VERB
ecletica-1329	173	8	compounds	compound	NOUN
ecletica-1329	173	9	ranged	range	VERB
ecletica-1329	173	10	from	from	ADP
ecletica-1329	173	11	–	–	PUNCT
ecletica-1329	173	12	0.13	0.13	NUM
ecletica-1329	173	13	(	(	PUNCT
ecletica-1329	173	14	5	5	NUM
ecletica-1329	173	15	-	-	PUNCT
ecletica-1329	173	16	fu	fu	NOUN
ecletica-1329	173	17	)	)	PUNCT
ecletica-1329	173	18	to	to	ADP
ecletica-1329	173	19	5.77	5.77	NUM
ecletica-1329	173	20	(	(	PUNCT
ecletica-1329	173	21	c4	c4	NOUN
ecletica-1329	173	22	)	)	PUNCT
ecletica-1329	173	23	,	,	PUNCT
ecletica-1329	173	24	which	which	PRON
ecletica-1329	173	25	revealed	reveal	VERB
ecletica-1329	173	26	that	that	SCONJ
ecletica-1329	173	27	c4	c4	NOUN
ecletica-1329	173	28	is	be	AUX
ecletica-1329	173	29	not	not	PART
ecletica-1329	173	30	as	as	ADV
ecletica-1329	173	31	soluble	soluble	ADJ
ecletica-1329	173	32	as	as	ADP
ecletica-1329	173	33	the	the	DET
ecletica-1329	173	34	referenced	referenced	ADJ
ecletica-1329	173	35	drug	drug	NOUN
ecletica-1329	173	36	(	(	PUNCT
ecletica-1329	173	37	table	table	NOUN
ecletica-1329	173	38	9	9	NUM
ecletica-1329	173	39	)	)	PUNCT
ecletica-1329	173	40	.	.	PUNCT
ecletica-1329	174	1	the	the	DET
ecletica-1329	174	2	silicos	silico	NOUN
ecletica-1329	174	3	-	-	PUNCT
ecletica-1329	174	4	it	it	PRON
ecletica-1329	174	5	prediction	prediction	NOUN
ecletica-1329	174	6	model	model	NOUN
ecletica-1329	174	7	was	be	AUX
ecletica-1329	174	8	used	use	VERB
ecletica-1329	174	9	to	to	PART
ecletica-1329	174	10	calculate	calculate	VERB
ecletica-1329	174	11	water	water	NOUN
ecletica-1329	174	12	solubility	solubility	NOUN
ecletica-1329	174	13	as	as	ADP
ecletica-1329	174	14	the	the	DET
ecletica-1329	174	15	logarithm	logarithm	NOUN
ecletica-1329	174	16	of	of	ADP
ecletica-1329	174	17	molar	molar	ADJ
ecletica-1329	174	18	solubility	solubility	NOUN
ecletica-1329	174	19	in	in	ADP
ecletica-1329	174	20	water	water	NOUN
ecletica-1329	174	21	(	(	PUNCT
ecletica-1329	174	22	log	log	VERB
ecletica-1329	174	23	s	s	PART
ecletica-1329	174	24	)	)	PUNCT
ecletica-1329	174	25	.	.	PUNCT
ecletica-1329	175	1	the	the	DET
ecletica-1329	175	2	log	log	NOUN
ecletica-1329	175	3	s	s	NOUN
ecletica-1329	175	4	value	value	NOUN
ecletica-1329	175	5	of	of	ADP
ecletica-1329	175	6	a	a	DET
ecletica-1329	175	7	drug	drug	NOUN
ecletica-1329	175	8	affects	affect	VERB
ecletica-1329	175	9	its	its	PRON
ecletica-1329	175	10	capacity	capacity	NOUN
ecletica-1329	175	11	to	to	PART
ecletica-1329	175	12	dissolve	dissolve	VERB
ecletica-1329	175	13	,	,	PUNCT
ecletica-1329	175	14	and	and	CCONJ
ecletica-1329	175	15	the	the	DET
ecletica-1329	175	16	lower	low	ADJ
ecletica-1329	175	17	the	the	DET
ecletica-1329	175	18	value	value	NOUN
ecletica-1329	175	19	,	,	PUNCT
ecletica-1329	175	20	the	the	PRON
ecletica-1329	175	21	better	well	ADJ
ecletica-1329	175	22	(	(	PUNCT
ecletica-1329	175	23	darvas	darvas	PROPN
ecletica-1329	175	24	et	et	PROPN
ecletica-1329	175	25	al	al	PROPN
ecletica-1329	175	26	.	.	PROPN
ecletica-1329	175	27	,	,	PUNCT
ecletica-1329	175	28	2002	2002	NUM
ecletica-1329	175	29	)	)	PUNCT
ecletica-1329	175	30	.	.	PUNCT
ecletica-1329	176	1	the	the	DET
ecletica-1329	176	2	compounds	compound	NOUN
ecletica-1329	176	3	had	have	VERB
ecletica-1329	176	4	log	log	NOUN
ecletica-1329	176	5	s	s	NOUN
ecletica-1329	176	6	values	value	NOUN
ecletica-1329	176	7	ranging	range	VERB
ecletica-1329	176	8	from	from	ADP
ecletica-1329	176	9	–	–	PUNCT
ecletica-1329	176	10	0.76	0.76	NUM
ecletica-1329	176	11	(	(	PUNCT
ecletica-1329	176	12	poorly	poorly	ADV
ecletica-1329	176	13	soluble	soluble	ADJ
ecletica-1329	176	14	,	,	PUNCT
ecletica-1329	176	15	c4	c4	NOUN
ecletica-1329	176	16	)	)	PUNCT
ecletica-1329	176	17	to	to	ADP
ecletica-1329	176	18	–	–	PUNCT
ecletica-1329	176	19	3.5	3.5	NUM
ecletica-1329	176	20	(	(	PUNCT
ecletica-1329	176	21	soluble	soluble	ADJ
ecletica-1329	176	22	,	,	PUNCT
ecletica-1329	176	23	c10	c10	PROPN
ecletica-1329	176	24	)	)	PUNCT
ecletica-1329	176	25	indicating	indicate	VERB
ecletica-1329	176	26	.	.	PUNCT
ecletica-1329	177	1	this	this	DET
ecletica-1329	177	2	trend	trend	NOUN
ecletica-1329	177	3	is	be	AUX
ecletica-1329	177	4	in	in	ADP
ecletica-1329	177	5	accordance	accordance	NOUN
ecletica-1329	177	6	with	with	ADP
ecletica-1329	177	7	the	the	DET
ecletica-1329	177	8	values	value	NOUN
ecletica-1329	177	9	of	of	ADP
ecletica-1329	177	10	log	log	NOUN
ecletica-1329	177	11	p	p	NOUN
ecletica-1329	177	12	earlier	early	ADV
ecletica-1329	177	13	discussed	discuss	VERB
ecletica-1329	177	14	.	.	PUNCT
ecletica-1329	178	1	the	the	DET
ecletica-1329	178	2	bioavailability	bioavailability	NOUN
ecletica-1329	178	3	score	score	NOUN
ecletica-1329	178	4	employs	employ	VERB
ecletica-1329	178	5	the	the	DET
ecletica-1329	178	6	total	total	ADJ
ecletica-1329	178	7	charge	charge	NOUN
ecletica-1329	178	8	,	,	PUNCT
ecletica-1329	178	9	the	the	DET
ecletica-1329	178	10	tpsa	tpsa	NOUN
ecletica-1329	178	11	,	,	PUNCT
ecletica-1329	178	12	and	and	CCONJ
ecletica-1329	178	13	the	the	DET
ecletica-1329	178	14	lipinski	lipinski	PROPN
ecletica-1329	178	15	filter	filter	NOUN
ecletica-1329	178	16	to	to	PART
ecletica-1329	178	17	provide	provide	VERB
ecletica-1329	178	18	a	a	DET
ecletica-1329	178	19	semiquantitative	semiquantitative	ADJ
ecletica-1329	178	20	indication	indication	NOUN
ecletica-1329	178	21	of	of	ADP
ecletica-1329	178	22	the	the	DET
ecletica-1329	178	23	compounds	compound	NOUN
ecletica-1329	178	24	’	'	PUNCT
ecletica-1329	178	25	https://revista.iq.unesp.br/index.php/ecletica	https://revista.iq.unesp.br/index.php/ecletica	PROPN
ecletica-1329	178	26	https://doi.org/10.26850/1678-4618eqj.v48.1.2023.p55-71	https://doi.org/10.26850/1678-4618eqj.v48.1.2023.p55-71	PROPN
ecletica-1329	178	27	original	original	ADJ
ecletica-1329	178	28	article	article	NOUN
ecletica-1329	178	29	revista.iq.unesp.br	revista.iq.unesp.br	PROPN
ecletica-1329	178	30	66	66	NUM
ecletica-1329	178	31	eclética	eclética	PROPN
ecletica-1329	178	32	química	química	PROPN
ecletica-1329	178	33	,	,	PUNCT
ecletica-1329	178	34	vol	vol	NOUN
ecletica-1329	178	35	.	.	PROPN
ecletica-1329	178	36	48	48	NUM
ecletica-1329	178	37	,	,	PUNCT
ecletica-1329	178	38	n.	n.	NOUN
ecletica-1329	178	39	1	1	NUM
ecletica-1329	178	40	,	,	PUNCT
ecletica-1329	178	41	2023	2023	NUM
ecletica-1329	178	42	,	,	PUNCT
ecletica-1329	178	43	55	55	NUM
ecletica-1329	178	44	-	-	SYM
ecletica-1329	178	45	71	71	NUM
ecletica-1329	178	46	issn	issn	NOUN
ecletica-1329	178	47	:	:	PUNCT
ecletica-1329	178	48	1678	1678	NUM
ecletica-1329	178	49	-	-	SYM
ecletica-1329	178	50	4618	4618	NUM
ecletica-1329	178	51	doi	doi	NOUN
ecletica-1329	178	52	:	:	PUNCT
ecletica-1329	178	53	10.26850/1678	10.26850/1678	NUM
ecletica-1329	178	54	-	-	PUNCT
ecletica-1329	178	55	4618eqj.v48.1.2023.p55	4618eqj.v48.1.2023.p55	NUM
ecletica-1329	178	56	-	-	PUNCT
ecletica-1329	178	57	71	71	NUM
ecletica-1329	178	58	likelihood	likelihood	NOUN
ecletica-1329	178	59	of	of	ADP
ecletica-1329	178	60	being	be	AUX
ecletica-1329	178	61	effective	effective	ADJ
ecletica-1329	178	62	oral	oral	ADJ
ecletica-1329	178	63	medicines	medicine	NOUN
ecletica-1329	178	64	(	(	PUNCT
ecletica-1329	178	65	testa	testa	NOUN
ecletica-1329	178	66	and	and	CCONJ
ecletica-1329	178	67	krämer	krämer	NOUN
ecletica-1329	178	68	,	,	PUNCT
ecletica-1329	178	69	2009	2009	NUM
ecletica-1329	178	70	)	)	PUNCT
ecletica-1329	178	71	.	.	PUNCT
ecletica-1329	179	1	the	the	PRON
ecletica-1329	179	2	less	less	ADJ
ecletica-1329	179	3	the	the	DET
ecletica-1329	179	4	drug	drug	NOUN
ecletica-1329	179	5	candidate	candidate	NOUN
ecletica-1329	179	6	can	can	AUX
ecletica-1329	179	7	penetrate	penetrate	VERB
ecletica-1329	179	8	,	,	PUNCT
ecletica-1329	179	9	the	the	PRON
ecletica-1329	179	10	higher	high	ADJ
ecletica-1329	179	11	the	the	DET
ecletica-1329	179	12	tpsa	tpsa	NOUN
ecletica-1329	179	13	and	and	CCONJ
ecletica-1329	179	14	molecular	molecular	ADJ
ecletica-1329	179	15	weight	weight	NOUN
ecletica-1329	179	16	values	value	NOUN
ecletica-1329	179	17	are	be	AUX
ecletica-1329	179	18	,	,	PUNCT
ecletica-1329	179	19	and	and	CCONJ
ecletica-1329	179	20	vice	vice	ADV
ecletica-1329	179	21	versa	versa	ADV
ecletica-1329	179	22	.	.	PUNCT
ecletica-1329	180	1	the	the	DET
ecletica-1329	180	2	bioavailability	bioavailability	NOUN
ecletica-1329	180	3	score	score	NOUN
ecletica-1329	180	4	of	of	ADP
ecletica-1329	180	5	the	the	DET
ecletica-1329	180	6	test	test	NOUN
ecletica-1329	180	7	compounds	compound	NOUN
ecletica-1329	180	8	is	be	AUX
ecletica-1329	180	9	0.55	0.55	NUM
ecletica-1329	180	10	,	,	PUNCT
ecletica-1329	180	11	which	which	PRON
ecletica-1329	180	12	means	mean	VERB
ecletica-1329	180	13	that	that	SCONJ
ecletica-1329	180	14	these	these	DET
ecletica-1329	180	15	compounds	compound	NOUN
ecletica-1329	180	16	have	have	VERB
ecletica-1329	180	17	a	a	DET
ecletica-1329	180	18	55	55	NUM
ecletica-1329	180	19	%	%	NOUN
ecletica-1329	180	20	chance	chance	NOUN
ecletica-1329	180	21	of	of	ADP
ecletica-1329	180	22	a	a	DET
ecletica-1329	180	23	minimum	minimum	NOUN
ecletica-1329	180	24	of	of	ADP
ecletica-1329	180	25	10	10	NUM
ecletica-1329	180	26	%	%	NOUN
ecletica-1329	180	27	oral	oral	ADJ
ecletica-1329	180	28	absorption	absorption	NOUN
ecletica-1329	180	29	in	in	ADP
ecletica-1329	180	30	rat	rat	NOUN
ecletica-1329	180	31	or	or	CCONJ
ecletica-1329	180	32	human	human	ADJ
ecletica-1329	180	33	colon	colon	NOUN
ecletica-1329	180	34	carcinoma	carcinoma	NOUN
ecletica-1329	180	35	(	(	PUNCT
ecletica-1329	180	36	caco-2	caco-2	NOUN
ecletica-1329	180	37	)	)	PUNCT
ecletica-1329	180	38	permeability	permeability	NOUN
ecletica-1329	180	39	(	(	PUNCT
ecletica-1329	180	40	testa	testa	PROPN
ecletica-1329	180	41	and	and	CCONJ
ecletica-1329	180	42	krämer	krämer	NOUN
ecletica-1329	180	43	,	,	PUNCT
ecletica-1329	180	44	2009	2009	NUM
ecletica-1329	180	45	)	)	PUNCT
ecletica-1329	180	46	indicating	indicate	VERB
ecletica-1329	180	47	that	that	SCONJ
ecletica-1329	180	48	they	they	PRON
ecletica-1329	180	49	could	could	AUX
ecletica-1329	180	50	be	be	AUX
ecletica-1329	180	51	useful	useful	ADJ
ecletica-1329	180	52	as	as	ADP
ecletica-1329	180	53	oral	oral	ADJ
ecletica-1329	180	54	drug	drug	NOUN
ecletica-1329	180	55	.	.	PUNCT
ecletica-1329	181	1	table	table	NOUN
ecletica-1329	181	2	9	9	NUM
ecletica-1329	181	3	.	.	PUNCT
ecletica-1329	181	4	predicted	predict	VERB
ecletica-1329	181	5	lipophilicity	lipophilicity	NOUN
ecletica-1329	181	6	(	(	PUNCT
ecletica-1329	181	7	log	log	VERB
ecletica-1329	181	8	p	p	NOUN
ecletica-1329	181	9	)	)	PUNCT
ecletica-1329	181	10	values	value	NOUN
ecletica-1329	181	11	,	,	PUNCT
ecletica-1329	181	12	water	water	NOUN
ecletica-1329	181	13	solubility	solubility	NOUN
ecletica-1329	181	14	and	and	CCONJ
ecletica-1329	181	15	bioavailability	bioavailability	NOUN
ecletica-1329	181	16	of	of	ADP
ecletica-1329	181	17	the	the	DET
ecletica-1329	181	18	studied	study	VERB
ecletica-1329	181	19	compounds	compound	NOUN
ecletica-1329	181	20	.	.	PUNCT
ecletica-1329	182	1	sample	sample	NOUN
ecletica-1329	182	2	code	code	PROPN
ecletica-1329	182	3	ilogp	ilogp	NOUN
ecletica-1329	182	4	xlogp3	xlogp3	PROPN
ecletica-1329	183	1	wlogp	wlogp	PROPN
ecletica-1329	183	2	mlogp	mlogp	PROPN
ecletica-1329	183	3	silicos	silico	NOUN
ecletica-1329	183	4	-	-	PUNCT
ecletica-1329	183	5	it	it	PRON
ecletica-1329	183	6	log	log	VERB
ecletica-1329	183	7	p	p	NOUN
ecletica-1329	183	8	consensus	consensus	NOUN
ecletica-1329	183	9	log	log	NOUN
ecletica-1329	183	10	p	p	NOUN
ecletica-1329	183	11	esol	esol	PROPN
ecletica-1329	183	12	log	log	NOUN
ecletica-1329	183	13	s	s	NOUN
ecletica-1329	183	14	solubility	solubility	NOUN
ecletica-1329	183	15	class	class	NOUN
ecletica-1329	183	16	bs	bs	PROPN
ecletica-1329	183	17	c1	c1	PROPN
ecletica-1329	183	18	3.13	3.13	NUM
ecletica-1329	183	19	4.33	4.33	NUM
ecletica-1329	183	20	4.17	4.17	NUM
ecletica-1329	183	21	2.23	2.23	NUM
ecletica-1329	183	22	5.03	5.03	NUM
ecletica-1329	183	23	3.78	3.78	NUM
ecletica-1329	183	24	–	–	PUNCT
ecletica-1329	183	25	4.79	4.79	NUM
ecletica-1329	183	26	moderately	moderately	ADV
ecletica-1329	183	27	soluble	soluble	ADJ
ecletica-1329	183	28	0.55	0.55	NUM
ecletica-1329	183	29	c2	c2	PROPN
ecletica-1329	183	30	2.08	2.08	NUM
ecletica-1329	183	31	3.27	3.27	NUM
ecletica-1329	183	32	3.11	3.11	NUM
ecletica-1329	183	33	2.17	2.17	NUM
ecletica-1329	183	34	3.64	3.64	NUM
ecletica-1329	183	35	2.85	2.85	NUM
ecletica-1329	183	36	–	–	PUNCT
ecletica-1329	183	37	4.18	4.18	NUM
ecletica-1329	183	38	moderately	moderately	ADV
ecletica-1329	183	39	soluble	soluble	ADJ
ecletica-1329	183	40	0.55	0.55	NUM
ecletica-1329	183	41	c3	c3	NOUN
ecletica-1329	183	42	3.45	3.45	NUM
ecletica-1329	183	43	5.37	5.37	NUM
ecletica-1329	183	44	5.34	5.34	NUM
ecletica-1329	183	45	3.96	3.96	NUM
ecletica-1329	183	46	6	6	NUM
ecletica-1329	183	47	4.82	4.82	NUM
ecletica-1329	183	48	–	–	PUNCT
ecletica-1329	183	49	6.11	6.11	NUM
ecletica-1329	183	50	poorly	poorly	ADV
ecletica-1329	183	51	soluble	soluble	ADJ
ecletica-1329	183	52	0.55	0.55	NUM
ecletica-1329	183	53	c4	c4	NOUN
ecletica-1329	183	54	3.15	3.15	NUM
ecletica-1329	183	55	6.5	6.5	NUM
ecletica-1329	183	56	6.58	6.58	NUM
ecletica-1329	183	57	5.03	5.03	NUM
ecletica-1329	183	58	7.58	7.58	NUM
ecletica-1329	183	59	5.77	5.77	NUM
ecletica-1329	183	60	–	–	PUNCT
ecletica-1329	183	61	7.06	7.06	NUM
ecletica-1329	183	62	poorly	poorly	ADV
ecletica-1329	183	63	soluble	soluble	ADJ
ecletica-1329	183	64	0.55	0.55	NUM
ecletica-1329	183	65	c5	c5	PROPN
ecletica-1329	183	66	3.25	3.25	NUM
ecletica-1329	183	67	5.61	5.61	NUM
ecletica-1329	183	68	5.58	5.58	NUM
ecletica-1329	183	69	4.29	4.29	NUM
ecletica-1329	183	70	6.83	6.83	NUM
ecletica-1329	183	71	5.11	5.11	NUM
ecletica-1329	183	72	–	–	PUNCT
ecletica-1329	183	73	6.17	6.17	NUM
ecletica-1329	183	74	poorly	poorly	ADV
ecletica-1329	183	75	soluble	soluble	ADJ
ecletica-1329	183	76	0.55	0.55	NUM
ecletica-1329	183	77	c6	c6	NOUN
ecletica-1329	183	78	2.18	2.18	NUM
ecletica-1329	183	79	4.58	4.58	NUM
ecletica-1329	183	80	4.02	4.02	NUM
ecletica-1329	183	81	3.31	3.31	NUM
ecletica-1329	183	82	5.62	5.62	NUM
ecletica-1329	183	83	3.94	3.94	NUM
ecletica-1329	183	84	–	–	PUNCT
ecletica-1329	183	85	5.73	5.73	NUM
ecletica-1329	183	86	moderately	moderately	ADV
ecletica-1329	183	87	soluble	soluble	ADJ
ecletica-1329	183	88	0.55	0.55	NUM
ecletica-1329	183	89	c7	c7	PROPN
ecletica-1329	183	90	2.46	2.46	NUM
ecletica-1329	183	91	5.21	5.21	NUM
ecletica-1329	183	92	4.68	4.68	NUM
ecletica-1329	183	93	3.78	3.78	NUM
ecletica-1329	183	94	6.26	6.26	NUM
ecletica-1329	183	95	4.48	4.48	NUM
ecletica-1329	183	96	–	–	PUNCT
ecletica-1329	183	97	6.33	6.33	NUM
ecletica-1329	183	98	poorly	poorly	ADV
ecletica-1329	183	99	soluble	soluble	ADJ
ecletica-1329	183	100	0.55	0.55	NUM
ecletica-1329	183	101	c8	c8	PROPN
ecletica-1329	183	102	2.35	2.35	NUM
ecletica-1329	183	103	5.27	5.27	NUM
ecletica-1329	183	104	4.78	4.78	NUM
ecletica-1329	183	105	3.88	3.88	NUM
ecletica-1329	183	106	6.3	6.3	NUM
ecletica-1329	183	107	4.52	4.52	NUM
ecletica-1329	183	108	–	–	PUNCT
ecletica-1329	183	109	6.64	6.64	NUM
ecletica-1329	183	110	poorly	poorly	ADV
ecletica-1329	183	111	soluble	soluble	ADJ
ecletica-1329	183	112	0.55	0.55	NUM
ecletica-1329	183	113	c9	c9	NOUN
ecletica-1329	183	114	3.44	3.44	NUM
ecletica-1329	183	115	3.96	3.96	NUM
ecletica-1329	183	116	3.46	3.46	NUM
ecletica-1329	183	117	1.6	1.6	NUM
ecletica-1329	183	118	4.72	4.72	NUM
ecletica-1329	183	119	3.44	3.44	NUM
ecletica-1329	183	120	–	–	PUNCT
ecletica-1329	183	121	4.57	4.57	NUM
ecletica-1329	183	122	moderately	moderately	ADV
ecletica-1329	183	123	soluble	soluble	ADJ
ecletica-1329	183	124	0.55	0.55	NUM
ecletica-1329	183	125	c10	c10	VERB
ecletica-1329	183	126	2.46	2.46	NUM
ecletica-1329	183	127	2.27	2.27	NUM
ecletica-1329	183	128	1.88	1.88	NUM
ecletica-1329	183	129	0.78	0.78	NUM
ecletica-1329	183	130	2.77	2.77	NUM
ecletica-1329	183	131	2.03	2.03	NUM
ecletica-1329	183	132	–	–	PUNCT
ecletica-1329	183	133	3.5	3.5	NUM
ecletica-1329	183	134	soluble	soluble	ADJ
ecletica-1329	183	135	0.55	0.55	NUM
ecletica-1329	183	136	c11	c11	NOUN
ecletica-1329	183	137	3.44	3.44	NUM
ecletica-1329	183	138	5.02	5.02	NUM
ecletica-1329	183	139	4.35	4.35	NUM
ecletica-1329	183	140	2.16	2.16	NUM
ecletica-1329	183	141	6.04	6.04	NUM
ecletica-1329	183	142	4.2	4.2	NUM
ecletica-1329	183	143	–	–	PUNCT
ecletica-1329	183	144	5.78	5.78	NUM
ecletica-1329	183	145	moderately	moderately	ADV
ecletica-1329	183	146	soluble	soluble	ADJ
ecletica-1329	183	147	0.55	0.55	NUM
ecletica-1329	183	148	c12	c12	NOUN
ecletica-1329	183	149	2.51	2.51	NUM
ecletica-1329	183	150	4.53	4.53	NUM
ecletica-1329	183	151	2.8	2.8	NUM
ecletica-1329	183	152	1.22	1.22	NUM
ecletica-1329	183	153	4.83	4.83	NUM
ecletica-1329	183	154	3.18	3.18	NUM
ecletica-1329	183	155	–	–	PUNCT
ecletica-1329	183	156	5.69	5.69	NUM
ecletica-1329	183	157	moderately	moderately	ADV
ecletica-1329	183	158	soluble	soluble	ADJ
ecletica-1329	183	159	0.55	0.55	NUM
ecletica-1329	183	160	c13	c13	NOUN
ecletica-1329	183	161	2.91	2.91	NUM
ecletica-1329	183	162	5.16	5.16	NUM
ecletica-1329	183	163	3.45	3.45	NUM
ecletica-1329	183	164	1.68	1.68	NUM
ecletica-1329	183	165	5.48	5.48	NUM
ecletica-1329	183	166	3.74	3.74	NUM
ecletica-1329	183	167	–	–	PUNCT
ecletica-1329	183	168	6.29	6.29	NUM
ecletica-1329	183	169	poorly	poorly	ADV
ecletica-1329	183	170	soluble	soluble	ADJ
ecletica-1329	183	171	0.55	0.55	NUM
ecletica-1329	183	172	c14	c14	NOUN
ecletica-1329	183	173	2.74	2.74	NUM
ecletica-1329	183	174	5.23	5.23	NUM
ecletica-1329	183	175	3.56	3.56	NUM
ecletica-1329	183	176	1.78	1.78	NUM
ecletica-1329	183	177	5.52	5.52	NUM
ecletica-1329	183	178	3.77	3.77	NUM
ecletica-1329	183	179	–	–	PUNCT
ecletica-1329	183	180	6.61	6.61	NUM
ecletica-1329	183	181	poorly	poorly	ADV
ecletica-1329	183	182	soluble	soluble	ADJ
ecletica-1329	183	183	0.55	0.55	NUM
ecletica-1329	183	184	5	5	NUM
ecletica-1329	183	185	-	-	PUNCT
ecletica-1329	183	186	fu	fu	NOUN
ecletica-1329	183	187	0.44	0.44	NUM
ecletica-1329	183	188	-0.89	-0.89	NOUN
ecletica-1329	183	189	-0.38	-0.38	PROPN
ecletica-1329	183	190	-0.32	-0.32	VERB
ecletica-1329	183	191	1.78	1.78	NUM
ecletica-1329	183	192	0.13	0.13	NUM
ecletica-1329	183	193	–	–	PUNCT
ecletica-1329	183	194	0.58	0.58	NUM
ecletica-1329	183	195	very	very	ADV
ecletica-1329	183	196	soluble	soluble	ADJ
ecletica-1329	183	197	0.55	0.55	NUM
ecletica-1329	183	198	5	5	NUM
ecletica-1329	183	199	-	-	PUNCT
ecletica-1329	183	200	flu	flu	NOUN
ecletica-1329	183	201	:	:	PUNCT
ecletica-1329	183	202	5	5	NUM
ecletica-1329	183	203	-	-	PUNCT
ecletica-1329	183	204	flurouracil	flurouracil	NOUN
ecletica-1329	183	205	;	;	PUNCT
ecletica-1329	183	206	bs	b	NOUN
ecletica-1329	183	207	:	:	PUNCT
ecletica-1329	183	208	bioavailability	bioavailability	NOUN
ecletica-1329	183	209	score	score	NOUN
ecletica-1329	183	210	.	.	PUNCT
ecletica-1329	184	1	table	table	NOUN
ecletica-1329	184	2	10	10	NUM
ecletica-1329	184	3	showed	show	VERB
ecletica-1329	184	4	the	the	DET
ecletica-1329	184	5	result	result	NOUN
ecletica-1329	184	6	of	of	ADP
ecletica-1329	184	7	pharmacokinetics	pharmacokinetic	NOUN
ecletica-1329	184	8	prediction	prediction	NOUN
ecletica-1329	184	9	of	of	ADP
ecletica-1329	184	10	the	the	DET
ecletica-1329	184	11	test	test	NOUN
ecletica-1329	184	12	molecules	molecule	NOUN
ecletica-1329	184	13	.	.	PUNCT
ecletica-1329	185	1	p	p	X
ecletica-1329	185	2	-	-	PUNCT
ecletica-1329	185	3	glycoprotein	glycoprotein	NOUN
ecletica-1329	185	4	(	(	PUNCT
ecletica-1329	185	5	p	p	NOUN
ecletica-1329	185	6	-	-	PUNCT
ecletica-1329	185	7	gp	gp	NOUN
ecletica-1329	185	8	)	)	PUNCT
ecletica-1329	185	9	,	,	PUNCT
ecletica-1329	185	10	a	a	DET
ecletica-1329	185	11	well	well	ADV
ecletica-1329	185	12	-	-	PUNCT
ecletica-1329	185	13	studied	study	VERB
ecletica-1329	185	14	plasma	plasma	NOUN
ecletica-1329	185	15	membrane	membrane	NOUN
ecletica-1329	185	16	atp	atp	NOUN
ecletica-1329	185	17	-	-	PUNCT
ecletica-1329	185	18	binding	bind	VERB
ecletica-1329	185	19	cassette	cassette	NOUN
ecletica-1329	185	20	transporter	transporter	NOUN
ecletica-1329	185	21	,	,	PUNCT
ecletica-1329	185	22	is	be	AUX
ecletica-1329	185	23	responsible	responsible	ADJ
ecletica-1329	185	24	for	for	ADP
ecletica-1329	185	25	the	the	DET
ecletica-1329	185	26	active	active	ADJ
ecletica-1329	185	27	efflux	efflux	NOUN
ecletica-1329	185	28	of	of	ADP
ecletica-1329	185	29	xenobiotics	xenobiotic	NOUN
ecletica-1329	185	30	through	through	ADP
ecletica-1329	185	31	biological	biological	ADJ
ecletica-1329	185	32	membranes	membrane	NOUN
ecletica-1329	185	33	to	to	PART
ecletica-1329	185	34	protect	protect	VERB
ecletica-1329	185	35	the	the	DET
ecletica-1329	185	36	body	body	NOUN
ecletica-1329	185	37	against	against	ADP
ecletica-1329	185	38	foreign	foreign	ADJ
ecletica-1329	185	39	substances	substance	NOUN
ecletica-1329	185	40	.	.	PUNCT
ecletica-1329	186	1	this	this	DET
ecletica-1329	186	2	efflux	efflux	NOUN
ecletica-1329	186	3	pump	pump	NOUN
ecletica-1329	186	4	contributes	contribute	VERB
ecletica-1329	186	5	to	to	ADP
ecletica-1329	186	6	drug	drug	NOUN
ecletica-1329	186	7	resistance	resistance	NOUN
ecletica-1329	186	8	by	by	ADP
ecletica-1329	186	9	preventing	prevent	VERB
ecletica-1329	186	10	some	some	DET
ecletica-1329	186	11	medications	medication	NOUN
ecletica-1329	186	12	from	from	ADP
ecletica-1329	186	13	entering	enter	VERB
ecletica-1329	186	14	sensitive	sensitive	ADJ
ecletica-1329	186	15	regions	region	NOUN
ecletica-1329	186	16	.	.	PUNCT
ecletica-1329	187	1	except	except	SCONJ
ecletica-1329	187	2	for	for	ADP
ecletica-1329	187	3	c13	c13	PROPN
ecletica-1329	187	4	and	and	CCONJ
ecletica-1329	187	5	c14	c14	NOUN
ecletica-1329	187	6	,	,	PUNCT
ecletica-1329	187	7	all	all	DET
ecletica-1329	187	8	the	the	DET
ecletica-1329	187	9	chemicals	chemical	NOUN
ecletica-1329	187	10	had	have	VERB
ecletica-1329	187	11	a	a	DET
ecletica-1329	187	12	high	high	ADJ
ecletica-1329	187	13	likelihood	likelihood	NOUN
ecletica-1329	187	14	of	of	ADP
ecletica-1329	187	15	being	be	AUX
ecletica-1329	187	16	absorbed	absorb	VERB
ecletica-1329	187	17	in	in	ADP
ecletica-1329	187	18	the	the	DET
ecletica-1329	187	19	gastrointestinal	gastrointestinal	ADJ
ecletica-1329	187	20	tract	tract	NOUN
ecletica-1329	187	21	.	.	PUNCT
ecletica-1329	188	1	this	this	PRON
ecletica-1329	188	2	shows	show	VERB
ecletica-1329	188	3	that	that	SCONJ
ecletica-1329	188	4	when	when	SCONJ
ecletica-1329	188	5	these	these	DET
ecletica-1329	188	6	chemicals	chemical	NOUN
ecletica-1329	188	7	are	be	AUX
ecletica-1329	188	8	taken	take	VERB
ecletica-1329	188	9	orally	orally	ADV
ecletica-1329	188	10	,	,	PUNCT
ecletica-1329	188	11	they	they	PRON
ecletica-1329	188	12	have	have	VERB
ecletica-1329	188	13	the	the	DET
ecletica-1329	188	14	potential	potential	NOUN
ecletica-1329	188	15	to	to	PART
ecletica-1329	188	16	be	be	AUX
ecletica-1329	188	17	absorbed	absorb	VERB
ecletica-1329	188	18	in	in	ADP
ecletica-1329	188	19	the	the	DET
ecletica-1329	188	20	gastrointestinal	gastrointestinal	ADJ
ecletica-1329	188	21	tract	tract	NOUN
ecletica-1329	188	22	(	(	PUNCT
ecletica-1329	188	23	lynch	lynch	NOUN
ecletica-1329	188	24	and	and	CCONJ
ecletica-1329	188	25	price	price	NOUN
ecletica-1329	188	26	,	,	PUNCT
ecletica-1329	188	27	2007	2007	NUM
ecletica-1329	188	28	)	)	PUNCT
ecletica-1329	188	29	.	.	PUNCT
ecletica-1329	189	1	the	the	DET
ecletica-1329	189	2	enzyme	enzyme	NOUN
ecletica-1329	189	3	cytochrome	cytochrome	ADJ
ecletica-1329	189	4	p450	p450	NUM
ecletica-1329	189	5	monooxygenase	monooxygenase	NOUN
ecletica-1329	189	6	plays	play	VERB
ecletica-1329	189	7	an	an	DET
ecletica-1329	189	8	important	important	ADJ
ecletica-1329	189	9	role	role	NOUN
ecletica-1329	189	10	in	in	ADP
ecletica-1329	189	11	the	the	DET
ecletica-1329	189	12	metabolism	metabolism	NOUN
ecletica-1329	189	13	and	and	CCONJ
ecletica-1329	189	14	removal	removal	NOUN
ecletica-1329	189	15	of	of	ADP
ecletica-1329	189	16	drugs	drug	NOUN
ecletica-1329	189	17	.	.	PUNCT
ecletica-1329	190	1	it	it	PRON
ecletica-1329	190	2	is	be	AUX
ecletica-1329	190	3	a	a	DET
ecletica-1329	190	4	group	group	NOUN
ecletica-1329	190	5	of	of	ADP
ecletica-1329	190	6	isoenzymes	isoenzyme	NOUN
ecletica-1329	190	7	that	that	PRON
ecletica-1329	190	8	catalyzes	catalyze	VERB
ecletica-1329	190	9	several	several	ADJ
ecletica-1329	190	10	processes	process	NOUN
ecletica-1329	190	11	in	in	ADP
ecletica-1329	190	12	the	the	DET
ecletica-1329	190	13	first	first	ADJ
ecletica-1329	190	14	phase	phase	NOUN
ecletica-1329	190	15	of	of	ADP
ecletica-1329	190	16	drug	drug	NOUN
ecletica-1329	190	17	metabolism	metabolism	NOUN
ecletica-1329	190	18	(	(	PUNCT
ecletica-1329	190	19	hollenberg	hollenberg	PROPN
ecletica-1329	190	20	,	,	PUNCT
ecletica-1329	190	21	2002	2002	NUM
ecletica-1329	190	22	)	)	PUNCT
ecletica-1329	190	23	.	.	PUNCT
ecletica-1329	191	1	the	the	DET
ecletica-1329	191	2	suppression	suppression	NOUN
ecletica-1329	191	3	of	of	ADP
ecletica-1329	191	4	five	five	NUM
ecletica-1329	191	5	main	main	ADJ
ecletica-1329	191	6	isoforms	isoform	NOUN
ecletica-1329	191	7	(	(	PUNCT
ecletica-1329	191	8	cyp1a2	cyp1a2	PROPN
ecletica-1329	191	9	,	,	PUNCT
ecletica-1329	191	10	cyp2c19	cyp2c19	PROPN
ecletica-1329	191	11	,	,	PUNCT
ecletica-1329	191	12	cyp2c9	cyp2c9	NOUN
ecletica-1329	191	13	,	,	PUNCT
ecletica-1329	191	14	cyp2d6	cyp2d6	NOUN
ecletica-1329	191	15	,	,	PUNCT
ecletica-1329	191	16	and	and	CCONJ
ecletica-1329	191	17	cyp3a4	cyp3a4	PROPN
ecletica-1329	191	18	)	)	PUNCT
ecletica-1329	191	19	,	,	PUNCT
ecletica-1329	191	20	which	which	PRON
ecletica-1329	191	21	are	be	AUX
ecletica-1329	191	22	substrates	substrate	NOUN
ecletica-1329	191	23	of	of	ADP
ecletica-1329	191	24	50–90	50–90	NUM
ecletica-1329	191	25	%	%	NOUN
ecletica-1329	191	26	of	of	ADP
ecletica-1329	191	27	medications	medication	NOUN
ecletica-1329	191	28	and	and	CCONJ
ecletica-1329	191	29	primary	primary	ADJ
ecletica-1329	191	30	sources	source	NOUN
ecletica-1329	191	31	of	of	ADP
ecletica-1329	191	32	pharmacokineticsrelated	pharmacokineticsrelate	VERB
ecletica-1329	191	33	drug	drug	NOUN
ecletica-1329	191	34	-	-	PUNCT
ecletica-1329	191	35	drug	drug	NOUN
ecletica-1329	191	36	interactions	interaction	NOUN
ecletica-1329	191	37	.	.	PUNCT
ecletica-1329	192	1	because	because	SCONJ
ecletica-1329	192	2	these	these	DET
ecletica-1329	192	3	enzymes	enzyme	NOUN
ecletica-1329	192	4	are	be	AUX
ecletica-1329	192	5	not	not	PART
ecletica-1329	192	6	inhibited	inhibit	VERB
ecletica-1329	192	7	,	,	PUNCT
ecletica-1329	192	8	the	the	DET
ecletica-1329	192	9	chemicals	chemical	NOUN
ecletica-1329	192	10	have	have	VERB
ecletica-1329	192	11	a	a	DET
ecletica-1329	192	12	high	high	ADJ
ecletica-1329	192	13	chance	chance	NOUN
ecletica-1329	192	14	of	of	ADP
ecletica-1329	192	15	being	be	AUX
ecletica-1329	192	16	converted	convert	VERB
ecletica-1329	192	17	and	and	CCONJ
ecletica-1329	192	18	,	,	PUNCT
ecletica-1329	192	19	as	as	ADP
ecletica-1329	192	20	a	a	DET
ecletica-1329	192	21	result	result	NOUN
ecletica-1329	192	22	,	,	PUNCT
ecletica-1329	192	23	of	of	ADP
ecletica-1329	192	24	becoming	become	VERB
ecletica-1329	192	25	bioavailable	bioavailable	ADJ
ecletica-1329	192	26	when	when	SCONJ
ecletica-1329	192	27	taken	take	VERB
ecletica-1329	192	28	orally	orally	ADV
ecletica-1329	192	29	.	.	PUNCT
ecletica-1329	193	1	inhibition	inhibition	NOUN
ecletica-1329	193	2	of	of	ADP
ecletica-1329	193	3	the	the	DET
ecletica-1329	193	4	cyp	cyp	ADJ
ecletica-1329	193	5	isomers	isomer	NOUN
ecletica-1329	193	6	by	by	ADP
ecletica-1329	193	7	the	the	DET
ecletica-1329	193	8	substances	substance	NOUN
ecletica-1329	193	9	,	,	PUNCT
ecletica-1329	193	10	on	on	ADP
ecletica-1329	193	11	the	the	DET
ecletica-1329	193	12	other	other	ADJ
ecletica-1329	193	13	hand	hand	NOUN
ecletica-1329	193	14	,	,	PUNCT
ecletica-1329	193	15	can	can	AUX
ecletica-1329	193	16	result	result	VERB
ecletica-1329	193	17	in	in	ADP
ecletica-1329	193	18	poor	poor	ADJ
ecletica-1329	193	19	bioavailability	bioavailability	NOUN
ecletica-1329	193	20	due	due	ADP
ecletica-1329	193	21	to	to	ADP
ecletica-1329	193	22	failure	failure	NOUN
ecletica-1329	193	23	to	to	PART
ecletica-1329	193	24	be	be	AUX
ecletica-1329	193	25	metabolized	metabolize	VERB
ecletica-1329	193	26	and	and	CCONJ
ecletica-1329	193	27	severe	severe	ADJ
ecletica-1329	193	28	side	side	NOUN
ecletica-1329	193	29	effects	effect	NOUN
ecletica-1329	193	30	due	due	ADJ
ecletica-1329	193	31	to	to	ADP
ecletica-1329	193	32	their	their	PRON
ecletica-1329	193	33	retention	retention	NOUN
ecletica-1329	193	34	(	(	PUNCT
ecletica-1329	193	35	sahin	sahin	PROPN
ecletica-1329	193	36	and	and	CCONJ
ecletica-1329	193	37	benet	benet	PROPN
ecletica-1329	193	38	,	,	PUNCT
ecletica-1329	193	39	2008	2008	NUM
ecletica-1329	193	40	)	)	PUNCT
ecletica-1329	193	41	.	.	PUNCT
ecletica-1329	194	1	compounds	compound	VERB
ecletica-1329	194	2	c1	c1	PROPN
ecletica-1329	194	3	,	,	PUNCT
ecletica-1329	194	4	c2	c2	PROPN
ecletica-1329	194	5	,	,	PUNCT
ecletica-1329	194	6	and	and	CCONJ
ecletica-1329	194	7	c9	c9	NOUN
ecletica-1329	194	8	are	be	AUX
ecletica-1329	194	9	potential	potential	ADJ
ecletica-1329	194	10	inhibitor	inhibitor	NOUN
ecletica-1329	194	11	of	of	ADP
ecletica-1329	194	12	cyp1a2	cyp1a2	NOUN
ecletica-1329	194	13	among	among	ADP
ecletica-1329	194	14	the	the	DET
ecletica-1329	194	15	tested	test	VERB
ecletica-1329	194	16	compounds	compound	NOUN
ecletica-1329	194	17	.	.	PUNCT
ecletica-1329	195	1	all	all	DET
ecletica-1329	195	2	the	the	DET
ecletica-1329	195	3	compounds	compound	NOUN
ecletica-1329	195	4	are	be	AUX
ecletica-1329	195	5	potential	potential	ADJ
ecletica-1329	195	6	inhibitor	inhibitor	NOUN
ecletica-1329	195	7	of	of	ADP
ecletica-1329	195	8	cyp2c19	cyp2c19	NOUN
ecletica-1329	195	9	except	except	SCONJ
ecletica-1329	195	10	compound	compound	PROPN
ecletica-1329	195	11	c2	c2	PROPN
ecletica-1329	195	12	,	,	PUNCT
ecletica-1329	195	13	c10	c10	VERB
ecletica-1329	195	14	,	,	PUNCT
ecletica-1329	195	15	and	and	CCONJ
ecletica-1329	195	16	standard	standard	ADJ
ecletica-1329	195	17	5	5	NUM
ecletica-1329	195	18	-	-	PUNCT
ecletica-1329	195	19	fu	fu	NOUN
ecletica-1329	195	20	.	.	PUNCT
ecletica-1329	196	1	as	as	SCONJ
ecletica-1329	196	2	shown	show	VERB
ecletica-1329	196	3	in	in	ADP
ecletica-1329	196	4	table	table	NOUN
ecletica-1329	196	5	10	10	NUM
ecletica-1329	196	6	,	,	PUNCT
ecletica-1329	196	7	only	only	ADV
ecletica-1329	196	8	compound	compound	NOUN
ecletica-1329	196	9	c2	c2	PROPN
ecletica-1329	196	10	and	and	CCONJ
ecletica-1329	196	11	5	5	NUM
ecletica-1329	196	12	-	-	PUNCT
ecletica-1329	196	13	fu	fu	NOUN
ecletica-1329	196	14	(	(	PUNCT
ecletica-1329	196	15	referenced	reference	VERB
ecletica-1329	196	16	drug	drug	NOUN
ecletica-1329	196	17	)	)	PUNCT
ecletica-1329	196	18	were	be	AUX
ecletica-1329	196	19	non	non	NOUN
ecletica-1329	196	20	-	-	NOUN
ecletica-1329	196	21	inhibitors	inhibitor	NOUN
ecletica-1329	196	22	of	of	ADP
ecletica-1329	196	23	cyp2c9	cyp2c9	NOUN
ecletica-1329	196	24	while	while	SCONJ
ecletica-1329	196	25	other	other	ADJ
ecletica-1329	196	26	studied	study	VERB
ecletica-1329	196	27	compounds	compound	NOUN
ecletica-1329	196	28	proved	prove	VERB
ecletica-1329	196	29	to	to	PART
ecletica-1329	196	30	possess	possess	VERB
ecletica-1329	196	31	the	the	DET
ecletica-1329	196	32	ability	ability	NOUN
ecletica-1329	196	33	to	to	PART
ecletica-1329	196	34	inhibit	inhibit	VERB
ecletica-1329	196	35	cyp2c19	cyp2c19	PROPN
ecletica-1329	196	36	.	.	PUNCT
ecletica-1329	197	1	compounds	compound	VERB
ecletica-1329	197	2	c1	c1	PROPN
ecletica-1329	197	3	,	,	PUNCT
ecletica-1329	197	4	c2	c2	PROPN
ecletica-1329	197	5	,	,	PUNCT
ecletica-1329	197	6	c3	c3	PROPN
ecletica-1329	197	7	,	,	PUNCT
ecletica-1329	197	8	c6	c6	PROPN
ecletica-1329	197	9	,	,	PUNCT
ecletica-1329	197	10	c9	c9	NOUN
ecletica-1329	197	11	,	,	PUNCT
ecletica-1329	197	12	and	and	CCONJ
ecletica-1329	197	13	c12	c12	PROPN
ecletica-1329	197	14	are	be	AUX
ecletica-1329	197	15	potential	potential	ADJ
ecletica-1329	197	16	inhibitor	inhibitor	NOUN
ecletica-1329	197	17	of	of	ADP
ecletica-1329	197	18	cyp2d6	cyp2d6	NOUN
ecletica-1329	197	19	while	while	SCONJ
ecletica-1329	197	20	others	other	NOUN
ecletica-1329	197	21	are	be	AUX
ecletica-1329	197	22	not	not	PART
ecletica-1329	197	23	.	.	PUNCT
ecletica-1329	198	1	all	all	DET
ecletica-1329	198	2	compounds	compound	NOUN
ecletica-1329	198	3	are	be	AUX
ecletica-1329	198	4	potential	potential	ADJ
ecletica-1329	198	5	inhibitors	inhibitor	NOUN
ecletica-1329	198	6	of	of	ADP
ecletica-1329	198	7	cyp3a4	cyp3a4	NOUN
ecletica-1329	198	8	,	,	PUNCT
ecletica-1329	198	9	except	except	SCONJ
ecletica-1329	198	10	compounds	compound	NOUN
ecletica-1329	198	11	c4	c4	PROPN
ecletica-1329	198	12	,	,	PUNCT
ecletica-1329	198	13	c7	c7	PROPN
ecletica-1329	198	14	,	,	PUNCT
ecletica-1329	198	15	c8	c8	PROPN
ecletica-1329	198	16	,	,	PUNCT
ecletica-1329	198	17	5	5	NUM
ecletica-1329	198	18	-	-	PUNCT
ecletica-1329	198	19	fu	fu	NOUN
ecletica-1329	198	20	.	.	PUNCT
ecletica-1329	199	1	it	it	PRON
ecletica-1329	199	2	was	be	AUX
ecletica-1329	199	3	observed	observe	VERB
ecletica-1329	199	4	that	that	SCONJ
ecletica-1329	199	5	the	the	DET
ecletica-1329	199	6	standard	standard	ADJ
ecletica-1329	199	7	5	5	NUM
ecletica-1329	199	8	-	-	PUNCT
ecletica-1329	199	9	fu	fu	NOUN
ecletica-1329	199	10	was	be	AUX
ecletica-1329	199	11	is	be	AUX
ecletica-1329	199	12	not	not	PART
ecletica-1329	199	13	an	an	DET
ecletica-1329	199	14	inhibitor	inhibitor	NOUN
ecletica-1329	199	15	of	of	ADP
ecletica-1329	199	16	any	any	DET
ecletica-1329	199	17	cytochrome	cytochrome	NOUN
ecletica-1329	199	18	p450	p450	NUM
ecletica-1329	199	19	,	,	PUNCT
ecletica-1329	199	20	which	which	PRON
ecletica-1329	199	21	suggests	suggest	VERB
ecletica-1329	199	22	that	that	SCONJ
ecletica-1329	199	23	the	the	DET
ecletica-1329	199	24	standard	standard	NOUN
ecletica-1329	199	25	is	be	AUX
ecletica-1329	199	26	more	more	ADV
ecletica-1329	199	27	likely	likely	ADJ
ecletica-1329	199	28	to	to	PART
ecletica-1329	199	29	be	be	AUX
ecletica-1329	199	30	converted	convert	VERB
ecletica-1329	199	31	and	and	CCONJ
ecletica-1329	199	32	bioavailable	bioavailable	ADJ
ecletica-1329	199	33	after	after	ADP
ecletica-1329	199	34	oral	oral	ADJ
ecletica-1329	199	35	delivery	delivery	NOUN
ecletica-1329	199	36	than	than	ADP
ecletica-1329	199	37	the	the	DET
ecletica-1329	199	38	compounds	compound	NOUN
ecletica-1329	199	39	investigated	investigate	VERB
ecletica-1329	199	40	.	.	PUNCT
ecletica-1329	200	1	the	the	DET
ecletica-1329	200	2	skin	skin	NOUN
ecletica-1329	200	3	is	be	AUX
ecletica-1329	200	4	a	a	DET
ecletica-1329	200	5	selective	selective	ADJ
ecletica-1329	200	6	barrier	barrier	NOUN
ecletica-1329	200	7	that	that	PRON
ecletica-1329	200	8	allows	allow	VERB
ecletica-1329	200	9	diverse	diverse	ADJ
ecletica-1329	200	10	compounds	compound	NOUN
ecletica-1329	200	11	to	to	PART
ecletica-1329	200	12	permeate	permeate	VERB
ecletica-1329	200	13	through	through	ADP
ecletica-1329	200	14	at	at	ADP
ecletica-1329	200	15	different	different	ADJ
ecletica-1329	200	16	rates	rate	NOUN
ecletica-1329	200	17	based	base	VERB
ecletica-1329	200	18	on	on	ADP
ecletica-1329	200	19	their	their	PRON
ecletica-1329	200	20	physicochemical	physicochemical	ADJ
ecletica-1329	200	21	properties	property	NOUN
ecletica-1329	200	22	(	(	PUNCT
ecletica-1329	200	23	dixon	dixon	PROPN
ecletica-1329	200	24	et	et	PROPN
ecletica-1329	200	25	al	al	PROPN
ecletica-1329	200	26	.	.	PROPN
ecletica-1329	200	27	,	,	PUNCT
ecletica-1329	200	28	2006	2006	NUM
ecletica-1329	200	29	)	)	PUNCT
ecletica-1329	200	30	.	.	PUNCT
ecletica-1329	201	1	hence	hence	ADV
ecletica-1329	201	2	,	,	PUNCT
ecletica-1329	201	3	the	the	DET
ecletica-1329	201	4	skin	skin	NOUN
ecletica-1329	201	5	permeability	permeability	NOUN
ecletica-1329	201	6	(	(	PUNCT
ecletica-1329	201	7	logkp	logkp	PROPN
ecletica-1329	201	8	)	)	PUNCT
ecletica-1329	201	9	is	be	AUX
ecletica-1329	201	10	a	a	DET
ecletica-1329	201	11	key	key	ADJ
ecletica-1329	201	12	parameter	parameter	NOUN
ecletica-1329	201	13	for	for	ADP
ecletica-1329	201	14	the	the	DET
ecletica-1329	201	15	evaluation	evaluation	NOUN
ecletica-1329	201	16	of	of	ADP
ecletica-1329	201	17	molecules	molecule	NOUN
ecletica-1329	201	18	that	that	PRON
ecletica-1329	201	19	might	might	AUX
ecletica-1329	201	20	require	require	VERB
ecletica-1329	201	21	transdermal	transdermal	ADJ
ecletica-1329	201	22	administration	administration	NOUN
ecletica-1329	201	23	(	(	PUNCT
ecletica-1329	201	24	dixon	dixon	PROPN
ecletica-1329	201	25	et	et	PROPN
ecletica-1329	201	26	al	al	PROPN
ecletica-1329	201	27	.	.	PROPN
ecletica-1329	201	28	,	,	PUNCT
ecletica-1329	201	29	2006	2006	NUM
ecletica-1329	201	30	)	)	PUNCT
ecletica-1329	201	31	.	.	PUNCT
ecletica-1329	202	1	the	the	DET
ecletica-1329	202	2	more	more	ADV
ecletica-1329	202	3	negative	negative	ADJ
ecletica-1329	202	4	the	the	DET
ecletica-1329	202	5	log	log	NOUN
ecletica-1329	202	6	kp	kp	X
ecletica-1329	202	7	(	(	PUNCT
ecletica-1329	202	8	with	with	ADP
ecletica-1329	202	9	kp	kp	PROPN
ecletica-1329	202	10	in	in	ADP
ecletica-1329	202	11	cm	cm	PROPN
ecletica-1329	202	12	s–1	s–1	PROPN
ecletica-1329	202	13	)	)	PUNCT
ecletica-1329	202	14	,	,	PUNCT
ecletica-1329	202	15	the	the	DET
ecletica-1329	202	16	less	less	ADJ
ecletica-1329	202	17	skin	skin	NOUN
ecletica-1329	202	18	permeant	permeant	ADJ
ecletica-1329	202	19	is	be	AUX
ecletica-1329	202	20	the	the	DET
ecletica-1329	202	21	molecule	molecule	NOUN
ecletica-1329	202	22	.	.	PUNCT
ecletica-1329	203	1	as	as	SCONJ
ecletica-1329	203	2	highlighted	highlight	VERB
ecletica-1329	203	3	in	in	ADP
ecletica-1329	203	4	table	table	NOUN
ecletica-1329	203	5	10	10	NUM
ecletica-1329	203	6	log	log	NOUN
ecletica-1329	203	7	kp	kp	PROPN
ecletica-1329	203	8	(	(	PUNCT
ecletica-1329	203	9	cm	cm	PROPN
ecletica-1329	203	10	s–1	s–1	NOUN
ecletica-1329	203	11	)	)	PUNCT
ecletica-1329	203	12	of	of	ADP
ecletica-1329	203	13	the	the	DET
ecletica-1329	203	14	test	test	NOUN
ecletica-1329	203	15	compounds	compound	NOUN
ecletica-1329	203	16	ranged	range	VERB
ecletica-1329	203	17	from	from	ADP
ecletica-1329	203	18	–	–	PUNCT
ecletica-1329	203	19	7.73	7.73	NUM
ecletica-1329	203	20	(	(	PUNCT
ecletica-1329	203	21	least	least	ADV
ecletica-1329	203	22	permeant	permeant	ADJ
ecletica-1329	203	23	)	)	PUNCT
ecletica-1329	203	24	to	to	ADP
ecletica-1329	203	25	–	–	PUNCT
ecletica-1329	203	26	4.62	4.62	NUM
ecletica-1329	203	27	(	(	PUNCT
ecletica-1329	203	28	most	most	ADV
ecletica-1329	203	29	permeant	permeant	ADJ
ecletica-1329	203	30	)	)	PUNCT
ecletica-1329	203	31	.	.	PUNCT
ecletica-1329	204	1	the	the	DET
ecletica-1329	204	2	skin	skin	NOUN
ecletica-1329	204	3	acts	act	VERB
ecletica-1329	204	4	as	as	ADP
ecletica-1329	204	5	a	a	DET
ecletica-1329	204	6	selective	selective	ADJ
ecletica-1329	204	7	barrier	barrier	NOUN
ecletica-1329	204	8	,	,	PUNCT
ecletica-1329	204	9	allowing	allow	VERB
ecletica-1329	204	10	various	various	ADJ
ecletica-1329	204	11	molecules	molecule	NOUN
ecletica-1329	204	12	to	to	PART
ecletica-1329	204	13	infiltrate	infiltrate	VERB
ecletica-1329	204	14	at	at	ADP
ecletica-1329	204	15	varied	varied	ADJ
ecletica-1329	204	16	rates	rate	NOUN
ecletica-1329	204	17	depending	depend	VERB
ecletica-1329	204	18	on	on	ADP
ecletica-1329	204	19	their	their	PRON
ecletica-1329	204	20	physicochemical	physicochemical	ADJ
ecletica-1329	204	21	qualities	quality	NOUN
ecletica-1329	204	22	(	(	PUNCT
ecletica-1329	204	23	cheng	cheng	PROPN
ecletica-1329	204	24	and	and	CCONJ
ecletica-1329	204	25	dixon	dixon	PROPN
ecletica-1329	204	26	,	,	PUNCT
ecletica-1329	204	27	2003	2003	NUM
ecletica-1329	204	28	)	)	PUNCT
ecletica-1329	204	29	.	.	PUNCT
ecletica-1329	205	1	as	as	ADP
ecletica-1329	205	2	a	a	DET
ecletica-1329	205	3	result	result	NOUN
ecletica-1329	205	4	,	,	PUNCT
ecletica-1329	205	5	skin	skin	NOUN
ecletica-1329	205	6	permeability	permeability	NOUN
ecletica-1329	205	7	(	(	PUNCT
ecletica-1329	205	8	logkp	logkp	PROPN
ecletica-1329	205	9	)	)	PUNCT
ecletica-1329	205	10	is	be	AUX
ecletica-1329	205	11	an	an	DET
ecletica-1329	205	12	important	important	ADJ
ecletica-1329	205	13	characteristic	characteristic	NOUN
ecletica-1329	205	14	to	to	PART
ecletica-1329	205	15	consider	consider	VERB
ecletica-1329	205	16	when	when	SCONJ
ecletica-1329	205	17	evaluating	evaluate	VERB
ecletica-1329	205	18	compounds	compound	VERB
ecletica-1329	205	19	https://revista.iq.unesp.br/index.php/ecletica	https://revista.iq.unesp.br/index.php/ecletica	PROPN
ecletica-1329	205	20	https://doi.org/10.26850/1678-4618eqj.v48.1.2023.p55-71	https://doi.org/10.26850/1678-4618eqj.v48.1.2023.p55-71	PROPN
ecletica-1329	205	21	original	original	ADJ
ecletica-1329	205	22	article	article	NOUN
ecletica-1329	205	23	revista.iq.unesp.br	revista.iq.unesp.br	PROPN
ecletica-1329	205	24	67	67	NUM
ecletica-1329	205	25	eclética	eclética	PROPN
ecletica-1329	205	26	química	química	PROPN
ecletica-1329	205	27	,	,	PUNCT
ecletica-1329	205	28	vol	vol	NOUN
ecletica-1329	205	29	.	.	PROPN
ecletica-1329	205	30	48	48	NUM
ecletica-1329	205	31	,	,	PUNCT
ecletica-1329	205	32	n.	n.	NOUN
ecletica-1329	205	33	1	1	NUM
ecletica-1329	205	34	,	,	PUNCT
ecletica-1329	205	35	2023	2023	NUM
ecletica-1329	205	36	,	,	PUNCT
ecletica-1329	205	37	55	55	NUM
ecletica-1329	205	38	-	-	SYM
ecletica-1329	205	39	71	71	NUM
ecletica-1329	205	40	issn	issn	NOUN
ecletica-1329	205	41	:	:	PUNCT
ecletica-1329	205	42	1678	1678	NUM
ecletica-1329	205	43	-	-	SYM
ecletica-1329	205	44	4618	4618	NUM
ecletica-1329	205	45	doi	doi	NOUN
ecletica-1329	205	46	:	:	PUNCT
ecletica-1329	205	47	10.26850/1678	10.26850/1678	NUM
ecletica-1329	205	48	-	-	PUNCT
ecletica-1329	205	49	4618eqj.v48.1.2023.p55	4618eqj.v48.1.2023.p55	NUM
ecletica-1329	205	50	-	-	PUNCT
ecletica-1329	205	51	71	71	NUM
ecletica-1329	205	52	that	that	PRON
ecletica-1329	205	53	may	may	AUX
ecletica-1329	205	54	need	need	VERB
ecletica-1329	205	55	to	to	PART
ecletica-1329	205	56	be	be	AUX
ecletica-1329	205	57	administered	administer	VERB
ecletica-1329	205	58	transdermally	transdermally	ADV
ecletica-1329	205	59	.	.	PUNCT
ecletica-1329	206	1	the	the	PRON
ecletica-1329	206	2	lower	low	ADJ
ecletica-1329	206	3	the	the	DET
ecletica-1329	206	4	log	log	NOUN
ecletica-1329	206	5	kp	kp	INTJ
ecletica-1329	206	6	(	(	PUNCT
ecletica-1329	206	7	in	in	ADP
ecletica-1329	206	8	cm	cm	PROPN
ecletica-1329	206	9	s–1	s–1	NOUN
ecletica-1329	206	10	)	)	PUNCT
ecletica-1329	206	11	,	,	PUNCT
ecletica-1329	206	12	the	the	DET
ecletica-1329	206	13	less	less	ADV
ecletica-1329	206	14	permeant	permeant	ADJ
ecletica-1329	206	15	the	the	DET
ecletica-1329	206	16	molecule	molecule	NOUN
ecletica-1329	206	17	is	be	AUX
ecletica-1329	206	18	to	to	ADP
ecletica-1329	206	19	the	the	DET
ecletica-1329	206	20	skin	skin	NOUN
ecletica-1329	206	21	.	.	PUNCT
ecletica-1329	207	1	the	the	DET
ecletica-1329	207	2	test	test	NOUN
ecletica-1329	207	3	compounds	compound	VERB
ecletica-1329	207	4	’	'	PUNCT
ecletica-1329	207	5	log	log	PROPN
ecletica-1329	207	6	kp	kp	PROPN
ecletica-1329	207	7	(	(	PUNCT
ecletica-1329	207	8	cm	cm	PROPN
ecletica-1329	207	9	s–1	s–1	NOUN
ecletica-1329	207	10	)	)	PUNCT
ecletica-1329	207	11	ranged	range	VERB
ecletica-1329	207	12	from	from	ADP
ecletica-1329	207	13	–	–	PUNCT
ecletica-1329	207	14	7.73	7.73	NUM
ecletica-1329	207	15	(	(	PUNCT
ecletica-1329	207	16	least	least	ADV
ecletica-1329	207	17	permeant	permeant	ADJ
ecletica-1329	207	18	)	)	PUNCT
ecletica-1329	207	19	to	to	ADP
ecletica-1329	207	20	–	–	PUNCT
ecletica-1329	207	21	4.62	4.62	NUM
ecletica-1329	207	22	(	(	PUNCT
ecletica-1329	207	23	most	most	ADV
ecletica-1329	207	24	permeant	permeant	ADJ
ecletica-1329	207	25	)	)	PUNCT
ecletica-1329	207	26	,	,	PUNCT
ecletica-1329	207	27	as	as	SCONJ
ecletica-1329	207	28	shown	show	VERB
ecletica-1329	207	29	in	in	ADP
ecletica-1329	207	30	table	table	NOUN
ecletica-1329	207	31	9	9	NUM
ecletica-1329	207	32	.	.	PUNCT
ecletica-1329	208	1	the	the	DET
ecletica-1329	208	2	values	value	NOUN
ecletica-1329	208	3	indicate	indicate	VERB
ecletica-1329	208	4	that	that	SCONJ
ecletica-1329	208	5	the	the	DET
ecletica-1329	208	6	compounds	compound	NOUN
ecletica-1329	208	7	show	show	VERB
ecletica-1329	208	8	low	low	ADJ
ecletica-1329	208	9	skin	skin	NOUN
ecletica-1329	208	10	permeability	permeability	NOUN
ecletica-1329	208	11	.	.	PUNCT
ecletica-1329	209	1	table	table	NOUN
ecletica-1329	209	2	10	10	NUM
ecletica-1329	209	3	.	.	PUNCT
ecletica-1329	210	1	pharmacokinetics	pharmacokinetic	NOUN
ecletica-1329	210	2	prediction	prediction	NOUN
ecletica-1329	210	3	output	output	NOUN
ecletica-1329	210	4	of	of	ADP
ecletica-1329	210	5	test	test	NOUN
ecletica-1329	210	6	compounds	compound	NOUN
ecletica-1329	210	7	.	.	PUNCT
ecletica-1329	211	1	sample	sample	NOUN
ecletica-1329	211	2	code	code	PROPN
ecletica-1329	211	3	gi	gi	NOUN
ecletica-1329	211	4	absorption	absorption	NOUN
ecletica-1329	211	5	p	p	X
ecletica-1329	211	6	–	–	PUNCT
ecletica-1329	211	7	gp	gp	NOUN
ecletica-1329	211	8	cyp	cyp	NOUN
ecletica-1329	211	9	1a2	1a2	NUM
ecletica-1329	211	10	inhibitor	inhibitor	NOUN
ecletica-1329	211	11	cyp2c19	cyp2c19	NOUN
ecletica-1329	211	12	inhibitor	inhibitor	NOUN
ecletica-1329	211	13	cyp2c9	cyp2c9	NOUN
ecletica-1329	211	14	inhibitor	inhibitor	NOUN
ecletica-1329	211	15	cyp2d6	cyp2d6	NOUN
ecletica-1329	211	16	inhibitor	inhibitor	NOUN
ecletica-1329	211	17	cyp3a4	cyp3a4	PROPN
ecletica-1329	211	18	inhibitor	inhibitor	PROPN
ecletica-1329	211	19	log	log	NOUN
ecletica-1329	211	20	kp	kp	PROPN
ecletica-1329	211	21	(	(	PUNCT
ecletica-1329	211	22	cm	cm	PROPN
ecletica-1329	211	23	s–1	s–1	NOUN
ecletica-1329	211	24	)	)	PUNCT
ecletica-1329	211	25	c1	c1	PROPN
ecletica-1329	211	26	high	high	ADV
ecletica-1329	212	1	no	no	INTJ
ecletica-1329	213	1	yes	yes	INTJ
ecletica-1329	214	1	yes	yes	INTJ
ecletica-1329	215	1	yes	yes	INTJ
ecletica-1329	216	1	no	no	INTJ
ecletica-1329	216	2	yes	yes	INTJ
ecletica-1329	216	3	–	–	PUNCT
ecletica-1329	216	4	5.23	5.23	NUM
ecletica-1329	216	5	c2	c2	PROPN
ecletica-1329	216	6	high	high	ADV
ecletica-1329	217	1	yes	yes	INTJ
ecletica-1329	217	2	yes	yes	INTJ
ecletica-1329	218	1	no	no	INTJ
ecletica-1329	219	1	no	no	INTJ
ecletica-1329	220	1	yes	yes	INTJ
ecletica-1329	220	2	yes	yes	INTJ
ecletica-1329	220	3	–	–	PUNCT
ecletica-1329	220	4	5.96	5.96	NUM
ecletica-1329	220	5	c3	c3	NOUN
ecletica-1329	220	6	high	high	ADV
ecletica-1329	221	1	yes	yes	INTJ
ecletica-1329	222	1	no	no	INTJ
ecletica-1329	223	1	yes	yes	INTJ
ecletica-1329	224	1	yes	yes	INTJ
ecletica-1329	225	1	yes	yes	INTJ
ecletica-1329	225	2	yes	yes	INTJ
ecletica-1329	225	3	–	–	PUNCT
ecletica-1329	225	4	5.27	5.27	NUM
ecletica-1329	225	5	c4	c4	NOUN
ecletica-1329	225	6	high	high	ADJ
ecletica-1329	226	1	yes	yes	INTJ
ecletica-1329	227	1	no	no	INTJ
ecletica-1329	228	1	yes	yes	INTJ
ecletica-1329	229	1	yes	yes	INTJ
ecletica-1329	230	1	no	no	INTJ
ecletica-1329	230	2	no	no	INTJ
ecletica-1329	230	3	–	–	PUNCT
ecletica-1329	230	4	4.62	4.62	NUM
ecletica-1329	230	5	c5	c5	PROPN
ecletica-1329	230	6	high	high	ADV
ecletica-1329	231	1	yes	yes	INTJ
ecletica-1329	232	1	no	no	INTJ
ecletica-1329	233	1	yes	yes	INTJ
ecletica-1329	234	1	yes	yes	INTJ
ecletica-1329	235	1	no	no	INTJ
ecletica-1329	235	2	yes	yes	INTJ
ecletica-1329	235	3	–	–	PUNCT
ecletica-1329	235	4	4.92	4.92	NUM
ecletica-1329	235	5	c6	c6	PROPN
ecletica-1329	235	6	high	high	ADV
ecletica-1329	236	1	yes	yes	INTJ
ecletica-1329	237	1	no	no	INTJ
ecletica-1329	238	1	yes	yes	INTJ
ecletica-1329	239	1	yes	yes	INTJ
ecletica-1329	240	1	yes	yes	INTJ
ecletica-1329	240	2	yes	yes	INTJ
ecletica-1329	240	3	–	–	PUNCT
ecletica-1329	240	4	5.81	5.81	NUM
ecletica-1329	240	5	c7	c7	PROPN
ecletica-1329	240	6	high	high	ADJ
ecletica-1329	241	1	yes	yes	INTJ
ecletica-1329	242	1	no	no	INTJ
ecletica-1329	243	1	yes	yes	INTJ
ecletica-1329	244	1	yes	yes	INTJ
ecletica-1329	245	1	no	no	INTJ
ecletica-1329	245	2	no	no	INTJ
ecletica-1329	245	3	–	–	PUNCT
ecletica-1329	245	4	5.58	5.58	NUM
ecletica-1329	245	5	c8	c8	NOUN
ecletica-1329	245	6	high	high	ADV
ecletica-1329	246	1	yes	yes	INTJ
ecletica-1329	247	1	no	no	INTJ
ecletica-1329	248	1	yes	yes	INTJ
ecletica-1329	249	1	yes	yes	INTJ
ecletica-1329	250	1	no	no	INTJ
ecletica-1329	250	2	no	no	INTJ
ecletica-1329	250	3	–	–	PUNCT
ecletica-1329	250	4	5.81	5.81	NUM
ecletica-1329	250	5	c9	c9	NOUN
ecletica-1329	250	6	high	high	ADV
ecletica-1329	251	1	no	no	INTJ
ecletica-1329	252	1	yes	yes	INTJ
ecletica-1329	253	1	yes	yes	INTJ
ecletica-1329	254	1	yes	yes	INTJ
ecletica-1329	255	1	yes	yes	INTJ
ecletica-1329	255	2	yes	yes	INTJ
ecletica-1329	255	3	–	–	PUNCT
ecletica-1329	255	4	5.91	5.91	NUM
ecletica-1329	255	5	c10	c10	VERB
ecletica-1329	255	6	high	high	ADV
ecletica-1329	256	1	yes	yes	INTJ
ecletica-1329	256	2	no	no	INTJ
ecletica-1329	257	1	no	no	INTJ
ecletica-1329	258	1	yes	yes	INTJ
ecletica-1329	259	1	no	no	INTJ
ecletica-1329	259	2	yes	yes	INTJ
ecletica-1329	259	3	–	–	PUNCT
ecletica-1329	259	4	7.02	7.02	NUM
ecletica-1329	259	5	c11	c11	NOUN
ecletica-1329	259	6	high	high	ADJ
ecletica-1329	260	1	yes	yes	INTJ
ecletica-1329	261	1	no	no	INTJ
ecletica-1329	262	1	yes	yes	INTJ
ecletica-1329	263	1	yes	yes	INTJ
ecletica-1329	264	1	yes	yes	INTJ
ecletica-1329	264	2	yes	yes	INTJ
ecletica-1329	264	3	–	–	PUNCT
ecletica-1329	264	4	5.69	5.69	NUM
ecletica-1329	264	5	c12	c12	NOUN
ecletica-1329	264	6	high	high	ADJ
ecletica-1329	265	1	yes	yes	INTJ
ecletica-1329	266	1	no	no	INTJ
ecletica-1329	267	1	yes	yes	INTJ
ecletica-1329	268	1	yes	yes	INTJ
ecletica-1329	269	1	yes	yes	INTJ
ecletica-1329	269	2	yes	yes	INTJ
ecletica-1329	269	3	–	–	PUNCT
ecletica-1329	269	4	6.2	6.2	NUM
ecletica-1329	269	5	c13	c13	NOUN
ecletica-1329	269	6	low	low	NOUN
ecletica-1329	270	1	yes	yes	INTJ
ecletica-1329	270	2	no	no	INTJ
ecletica-1329	271	1	yes	yes	INTJ
ecletica-1329	272	1	yes	yes	INTJ
ecletica-1329	273	1	no	no	INTJ
ecletica-1329	274	1	yes	yes	INTJ
ecletica-1329	274	2	–	–	PUNCT
ecletica-1329	274	3	5.97	5.97	NUM
ecletica-1329	274	4	c14	c14	NOUN
ecletica-1329	274	5	low	low	ADV
ecletica-1329	275	1	yes	yes	INTJ
ecletica-1329	275	2	no	no	INTJ
ecletica-1329	276	1	yes	yes	INTJ
ecletica-1329	277	1	yes	yes	INTJ
ecletica-1329	278	1	no	no	INTJ
ecletica-1329	278	2	yes	yes	INTJ
ecletica-1329	278	3	–	–	PUNCT
ecletica-1329	278	4	6.19	6.19	NUM
ecletica-1329	278	5	5	5	NUM
ecletica-1329	278	6	–	–	PUNCT
ecletica-1329	278	7	fu	fu	NOUN
ecletica-1329	278	8	high	high	ADJ
ecletica-1329	279	1	no	no	INTJ
ecletica-1329	279	2	no	no	INTJ
ecletica-1329	279	3	no	no	INTJ
ecletica-1329	279	4	no	no	INTJ
ecletica-1329	279	5	no	no	INTJ
ecletica-1329	280	1	no	no	INTJ
ecletica-1329	280	2	–	–	PUNCT
ecletica-1329	280	3	7.73	7.73	NUM
ecletica-1329	280	4	5	5	NUM
ecletica-1329	280	5	-	-	PUNCT
ecletica-1329	280	6	flu	flu	NOUN
ecletica-1329	280	7	:	:	PUNCT
ecletica-1329	280	8	5	5	NUM
ecletica-1329	280	9	-	-	PUNCT
ecletica-1329	280	10	flurouracil	flurouracil	NOUN
ecletica-1329	280	11	;	;	PUNCT
ecletica-1329	280	12	gi	gi	NOUN
ecletica-1329	280	13	:	:	PUNCT
ecletica-1329	280	14	gastrointestinal	gastrointestinal	ADJ
ecletica-1329	280	15	;	;	PUNCT
ecletica-1329	280	16	and	and	CCONJ
ecletica-1329	280	17	p	p	X
ecletica-1329	280	18	-	-	PUNCT
ecletica-1329	280	19	gp	gp	NOUN
ecletica-1329	280	20	:	:	PUNCT
ecletica-1329	280	21	p	p	NOUN
ecletica-1329	280	22	-	-	PUNCT
ecletica-1329	280	23	glycoprotein	glycoprotein	NOUN
ecletica-1329	280	24	.	.	PUNCT
ecletica-1329	281	1	the	the	DET
ecletica-1329	281	2	toxicity	toxicity	NOUN
ecletica-1329	281	3	prediction	prediction	NOUN
ecletica-1329	281	4	output	output	NOUN
ecletica-1329	281	5	of	of	ADP
ecletica-1329	281	6	the	the	DET
ecletica-1329	281	7	compounds	compound	NOUN
ecletica-1329	281	8	is	be	AUX
ecletica-1329	281	9	shown	show	VERB
ecletica-1329	281	10	in	in	ADP
ecletica-1329	281	11	table	table	NOUN
ecletica-1329	281	12	11	11	NUM
ecletica-1329	281	13	.	.	PUNCT
ecletica-1329	282	1	compounds	compound	VERB
ecletica-1329	282	2	c8	c8	PROPN
ecletica-1329	282	3	,	,	PUNCT
ecletica-1329	282	4	c12	c12	PROPN
ecletica-1329	282	5	,	,	PUNCT
ecletica-1329	282	6	c13	c13	PROPN
ecletica-1329	282	7	,	,	PUNCT
ecletica-1329	282	8	and	and	CCONJ
ecletica-1329	282	9	c14	c14	NOUN
ecletica-1329	282	10	fall	fall	VERB
ecletica-1329	282	11	under	under	ADP
ecletica-1329	282	12	the	the	DET
ecletica-1329	282	13	oral	oral	ADJ
ecletica-1329	282	14	toxicity	toxicity	NOUN
ecletica-1329	282	15	class	class	NOUN
ecletica-1329	282	16	5	5	NUM
ecletica-1329	282	17	,	,	PUNCT
ecletica-1329	282	18	while	while	SCONJ
ecletica-1329	282	19	other	other	ADJ
ecletica-1329	282	20	tested	test	VERB
ecletica-1329	282	21	compounds	compound	NOUN
ecletica-1329	282	22	fall	fall	VERB
ecletica-1329	282	23	under	under	ADP
ecletica-1329	282	24	oral	oral	ADJ
ecletica-1329	282	25	toxicity	toxicity	NOUN
ecletica-1329	282	26	class	class	NOUN
ecletica-1329	282	27	4	4	NUM
ecletica-1329	282	28	.	.	PUNCT
ecletica-1329	283	1	human	human	ADJ
ecletica-1329	283	2	hepatotoxicity	hepatotoxicity	NOUN
ecletica-1329	283	3	(	(	PUNCT
ecletica-1329	283	4	h	h	NOUN
ecletica-1329	283	5	-	-	PUNCT
ecletica-1329	283	6	ht	ht	NOUN
ecletica-1329	283	7	)	)	PUNCT
ecletica-1329	283	8	is	be	AUX
ecletica-1329	283	9	a	a	DET
ecletica-1329	283	10	term	term	NOUN
ecletica-1329	283	11	that	that	PRON
ecletica-1329	283	12	describes	describe	VERB
ecletica-1329	283	13	and	and	CCONJ
ecletica-1329	283	14	illustrates	illustrate	VERB
ecletica-1329	283	15	numerous	numerous	ADJ
ecletica-1329	283	16	types	type	NOUN
ecletica-1329	283	17	of	of	ADP
ecletica-1329	283	18	liver	liver	NOUN
ecletica-1329	283	19	damage	damage	NOUN
ecletica-1329	283	20	that	that	PRON
ecletica-1329	283	21	can	can	AUX
ecletica-1329	283	22	lead	lead	VERB
ecletica-1329	283	23	to	to	ADP
ecletica-1329	283	24	the	the	DET
ecletica-1329	283	25	organ	organ	NOUN
ecletica-1329	283	26	failing	failing	NOUN
ecletica-1329	283	27	or	or	CCONJ
ecletica-1329	283	28	death	death	NOUN
ecletica-1329	283	29	(	(	PUNCT
ecletica-1329	283	30	cheng	cheng	PROPN
ecletica-1329	283	31	and	and	CCONJ
ecletica-1329	283	32	dixon	dixon	PROPN
ecletica-1329	283	33	,	,	PUNCT
ecletica-1329	283	34	2003	2003	NUM
ecletica-1329	283	35	)	)	PUNCT
ecletica-1329	283	36	.	.	PUNCT
ecletica-1329	284	1	compounds	compound	NOUN
ecletica-1329	284	2	c10	c10	PROPN
ecletica-1329	284	3	,	,	PUNCT
ecletica-1329	284	4	c11	c11	NOUN
ecletica-1329	284	5	,	,	PUNCT
ecletica-1329	284	6	c12	c12	PROPN
ecletica-1329	284	7	,	,	PUNCT
ecletica-1329	284	8	c13	c13	PROPN
ecletica-1329	284	9	,	,	PUNCT
ecletica-1329	284	10	and	and	CCONJ
ecletica-1329	284	11	c14	c14	NOUN
ecletica-1329	284	12	were	be	AUX
ecletica-1329	284	13	hepatotoxic	hepatotoxic	ADJ
ecletica-1329	284	14	.	.	PUNCT
ecletica-1329	285	1	carcinogenicity	carcinogenicity	NOUN
ecletica-1329	285	2	compounds	compound	NOUN
ecletica-1329	285	3	can	can	AUX
ecletica-1329	285	4	damage	damage	VERB
ecletica-1329	285	5	the	the	DET
ecletica-1329	285	6	genome	genome	NOUN
ecletica-1329	285	7	,	,	PUNCT
ecletica-1329	285	8	the	the	DET
ecletica-1329	285	9	disrupt	disrupt	ADJ
ecletica-1329	285	10	cellular	cellular	ADJ
ecletica-1329	285	11	metabolic	metabolic	NOUN
ecletica-1329	285	12	processes	process	NOUN
ecletica-1329	285	13	and	and	CCONJ
ecletica-1329	285	14	cause	cause	VERB
ecletica-1329	285	15	cancer	cancer	NOUN
ecletica-1329	285	16	.	.	PUNCT
ecletica-1329	286	1	compounds	compound	VERB
ecletica-1329	286	2	c2	c2	PROPN
ecletica-1329	286	3	,	,	PUNCT
ecletica-1329	286	4	c3	c3	PROPN
ecletica-1329	286	5	,	,	PUNCT
ecletica-1329	286	6	c4	c4	NOUN
ecletica-1329	286	7	,	,	PUNCT
ecletica-1329	286	8	c5	c5	PROPN
ecletica-1329	286	9	,	,	PUNCT
ecletica-1329	286	10	c6	c6	PROPN
ecletica-1329	286	11	,	,	PUNCT
ecletica-1329	286	12	c11	c11	NOUN
ecletica-1329	286	13	,	,	PUNCT
ecletica-1329	286	14	c12	c12	PROPN
ecletica-1329	286	15	and	and	CCONJ
ecletica-1329	286	16	the	the	DET
ecletica-1329	286	17	standard	standard	NOUN
ecletica-1329	286	18	are	be	AUX
ecletica-1329	286	19	carcinogenic	carcinogenic	ADJ
ecletica-1329	286	20	.	.	PUNCT
ecletica-1329	287	1	immunotoxicity	immunotoxicity	NOUN
ecletica-1329	287	2	is	be	AUX
ecletica-1329	287	3	defined	define	VERB
ecletica-1329	287	4	as	as	ADP
ecletica-1329	287	5	the	the	DET
ecletica-1329	287	6	negative	negative	ADJ
ecletica-1329	287	7	impact	impact	NOUN
ecletica-1329	287	8	of	of	ADP
ecletica-1329	287	9	toxic	toxic	ADJ
ecletica-1329	287	10	compounds	compound	NOUN
ecletica-1329	287	11	on	on	ADP
ecletica-1329	287	12	the	the	DET
ecletica-1329	287	13	functioning	functioning	NOUN
ecletica-1329	287	14	of	of	ADP
ecletica-1329	287	15	both	both	CCONJ
ecletica-1329	287	16	the	the	DET
ecletica-1329	287	17	local	local	ADJ
ecletica-1329	287	18	and	and	CCONJ
ecletica-1329	287	19	systemic	systemic	ADJ
ecletica-1329	287	20	immune	immune	ADJ
ecletica-1329	287	21	systems	system	NOUN
ecletica-1329	287	22	.	.	PUNCT
ecletica-1329	288	1	only	only	ADV
ecletica-1329	288	2	compounds	compound	VERB
ecletica-1329	288	3	c1	c1	PROPN
ecletica-1329	288	4	,	,	PUNCT
ecletica-1329	288	5	c9	c9	PROPN
ecletica-1329	288	6	,	,	PUNCT
ecletica-1329	288	7	c10	c10	VERB
ecletica-1329	288	8	and	and	CCONJ
ecletica-1329	288	9	the	the	DET
ecletica-1329	288	10	standard	standard	NOUN
ecletica-1329	288	11	are	be	AUX
ecletica-1329	288	12	nonimmunotoxic	nonimmunotoxic	ADJ
ecletica-1329	288	13	.	.	PUNCT
ecletica-1329	289	1	the	the	DET
ecletica-1329	289	2	mutagenicity	mutagenicity	NOUN
ecletica-1329	289	3	test	test	NOUN
ecletica-1329	289	4	is	be	AUX
ecletica-1329	289	5	used	use	VERB
ecletica-1329	289	6	to	to	PART
ecletica-1329	289	7	identify	identify	VERB
ecletica-1329	289	8	substances	substance	NOUN
ecletica-1329	289	9	that	that	PRON
ecletica-1329	289	10	can	can	AUX
ecletica-1329	289	11	cause	cause	VERB
ecletica-1329	289	12	mutations	mutation	NOUN
ecletica-1329	289	13	or	or	CCONJ
ecletica-1329	289	14	malignant	malignant	ADJ
ecletica-1329	289	15	growth	growth	NOUN
ecletica-1329	289	16	in	in	ADP
ecletica-1329	289	17	humans	human	NOUN
ecletica-1329	289	18	(	(	PUNCT
ecletica-1329	289	19	loving	love	VERB
ecletica-1329	289	20	et	et	PROPN
ecletica-1329	289	21	al	al	PROPN
ecletica-1329	289	22	.	.	PROPN
ecletica-1329	289	23	,	,	PUNCT
ecletica-1329	289	24	2009	2009	NUM
ecletica-1329	289	25	)	)	PUNCT
ecletica-1329	289	26	.	.	PUNCT
ecletica-1329	290	1	compounds	compound	VERB
ecletica-1329	290	2	c2	c2	PROPN
ecletica-1329	290	3	,	,	PUNCT
ecletica-1329	290	4	c3	c3	PROPN
ecletica-1329	290	5	,	,	PUNCT
ecletica-1329	290	6	c4	c4	NOUN
ecletica-1329	290	7	,	,	PUNCT
ecletica-1329	290	8	c5	c5	PROPN
ecletica-1329	290	9	,	,	PUNCT
ecletica-1329	290	10	c6	c6	PROPN
ecletica-1329	290	11	,	,	PUNCT
ecletica-1329	290	12	and	and	CCONJ
ecletica-1329	290	13	c12	c12	PROPN
ecletica-1329	290	14	are	be	AUX
ecletica-1329	290	15	mutagenic	mutagenic	ADJ
ecletica-1329	290	16	,	,	PUNCT
ecletica-1329	290	17	and	and	CCONJ
ecletica-1329	290	18	only	only	ADV
ecletica-1329	290	19	compound	compound	NOUN
ecletica-1329	290	20	c2	c2	PROPN
ecletica-1329	290	21	is	be	AUX
ecletica-1329	290	22	cytotoxic	cytotoxic	ADJ
ecletica-1329	290	23	among	among	ADP
ecletica-1329	290	24	the	the	DET
ecletica-1329	290	25	test	test	NOUN
ecletica-1329	290	26	compounds	compound	NOUN
ecletica-1329	290	27	.	.	PUNCT
ecletica-1329	291	1	the	the	DET
ecletica-1329	291	2	study	study	NOUN
ecletica-1329	291	3	clearly	clearly	ADV
ecletica-1329	291	4	revealed	reveal	VERB
ecletica-1329	291	5	that	that	SCONJ
ecletica-1329	291	6	most	most	ADJ
ecletica-1329	291	7	of	of	ADP
ecletica-1329	291	8	the	the	DET
ecletica-1329	291	9	compounds	compound	NOUN
ecletica-1329	291	10	possess	possess	VERB
ecletica-1329	291	11	one	one	NUM
ecletica-1329	291	12	form	form	NOUN
ecletica-1329	291	13	of	of	ADP
ecletica-1329	291	14	toxicity	toxicity	NOUN
ecletica-1329	291	15	except	except	SCONJ
ecletica-1329	291	16	for	for	ADP
ecletica-1329	291	17	compounds	compound	NOUN
ecletica-1329	291	18	c1	c1	PROPN
ecletica-1329	291	19	and	and	CCONJ
ecletica-1329	291	20	c9	c9	PROPN
ecletica-1329	291	21	,	,	PUNCT
ecletica-1329	291	22	which	which	PRON
ecletica-1329	291	23	did	do	AUX
ecletica-1329	291	24	not	not	PART
ecletica-1329	291	25	show	show	VERB
ecletica-1329	291	26	any	any	DET
ecletica-1329	291	27	tendency	tendency	NOUN
ecletica-1329	291	28	for	for	ADP
ecletica-1329	291	29	hepatotoxicity	hepatotoxicity	NOUN
ecletica-1329	291	30	,	,	PUNCT
ecletica-1329	291	31	carcinogenicity	carcinogenicity	NOUN
ecletica-1329	291	32	,	,	PUNCT
ecletica-1329	291	33	immunotoxicity	immunotoxicity	NOUN
ecletica-1329	291	34	,	,	PUNCT
ecletica-1329	291	35	mutagenicity	mutagenicity	NOUN
ecletica-1329	291	36	and	and	CCONJ
ecletica-1329	291	37	cytotoxicity	cytotoxicity	NOUN
ecletica-1329	291	38	,	,	PUNCT
ecletica-1329	291	39	indicating	indicate	VERB
ecletica-1329	291	40	that	that	SCONJ
ecletica-1329	291	41	they	they	PRON
ecletica-1329	291	42	are	be	AUX
ecletica-1329	291	43	safe	safe	ADJ
ecletica-1329	291	44	as	as	ADP
ecletica-1329	291	45	possible	possible	ADJ
ecletica-1329	291	46	therapeutic	therapeutic	ADJ
ecletica-1329	291	47	agents	agent	NOUN
ecletica-1329	291	48	.	.	PUNCT
ecletica-1329	292	1	these	these	DET
ecletica-1329	292	2	two	two	NUM
ecletica-1329	292	3	compounds	compound	NOUN
ecletica-1329	292	4	did	do	AUX
ecletica-1329	292	5	not	not	PART
ecletica-1329	292	6	violate	violate	VERB
ecletica-1329	292	7	any	any	PRON
ecletica-1329	292	8	of	of	ADP
ecletica-1329	292	9	the	the	DET
ecletica-1329	292	10	base	base	NOUN
ecletica-1329	292	11	rule	rule	NOUN
ecletica-1329	292	12	filter	filter	NOUN
ecletica-1329	292	13	,	,	PUNCT
ecletica-1329	292	14	they	they	PRON
ecletica-1329	292	15	are	be	AUX
ecletica-1329	292	16	moderately	moderately	ADV
ecletica-1329	292	17	soluble	soluble	ADJ
ecletica-1329	292	18	and	and	CCONJ
ecletica-1329	292	19	not	not	PART
ecletica-1329	292	20	p	p	NOUN
ecletica-1329	292	21	-	-	PUNCT
ecletica-1329	292	22	gp	gp	NOUN
ecletica-1329	292	23	substate	substate	NOUN
ecletica-1329	292	24	.	.	PUNCT
ecletica-1329	293	1	table	table	NOUN
ecletica-1329	293	2	11	11	NUM
ecletica-1329	293	3	.	.	PUNCT
ecletica-1329	294	1	toxicity	toxicity	NOUN
ecletica-1329	294	2	profiles	profile	NOUN
ecletica-1329	294	3	of	of	ADP
ecletica-1329	294	4	test	test	NOUN
ecletica-1329	294	5	compounds	compound	NOUN
ecletica-1329	294	6	.	.	PUNCT
ecletica-1329	295	1	code	code	PROPN
ecletica-1329	295	2	c1	c1	PROPN
ecletica-1329	295	3	c2	c2	PROPN
ecletica-1329	295	4	c3	c3	PROPN
ecletica-1329	295	5	c4	c4	PROPN
ecletica-1329	295	6	c5	c5	PROPN
ecletica-1329	295	7	c6	c6	PROPN
ecletica-1329	295	8	c7	c7	PROPN
ecletica-1329	295	9	c8	c8	PROPN
ecletica-1329	295	10	c9	c9	PROPN
ecletica-1329	295	11	c10	c10	PROPN
ecletica-1329	295	12	c11	c11	PROPN
ecletica-1329	295	13	c12	c12	PROPN
ecletica-1329	295	14	c13	c13	PROPN
ecletica-1329	295	15	c14	c14	PROPN
ecletica-1329	295	16	5	5	NUM
ecletica-1329	295	17	–	–	PUNCT
ecletica-1329	295	18	fu	fu	NOUN
ecletica-1329	295	19	ld50	ld50	PROPN
ecletica-1329	295	20	(	(	PUNCT
ecletica-1329	295	21	mg	mg	PROPN
ecletica-1329	295	22	kg–1	kg–1	PROPN
ecletica-1329	295	23	)	)	PUNCT
ecletica-1329	295	24	753	753	NUM
ecletica-1329	295	25	1000	1000	NUM
ecletica-1329	295	26	1000	1000	NUM
ecletica-1329	295	27	1000	1000	NUM
ecletica-1329	295	28	1000	1000	NUM
ecletica-1329	295	29	1000	1000	NUM
ecletica-1329	295	30	1000	1000	NUM
ecletica-1329	295	31	4000	4000	NUM
ecletica-1329	295	32	750	750	NUM
ecletica-1329	295	33	750	750	NUM
ecletica-1329	295	34	750	750	NUM
ecletica-1329	295	35	3000	3000	NUM
ecletica-1329	295	36	2001	2001	NUM
ecletica-1329	295	37	3009	3009	NUM
ecletica-1329	295	38	1923	1923	NUM
ecletica-1329	295	39	toxicity	toxicity	NOUN
ecletica-1329	295	40	class	class	NOUN
ecletica-1329	295	41	4	4	NUM
ecletica-1329	295	42	4	4	NUM
ecletica-1329	295	43	4	4	NUM
ecletica-1329	295	44	4	4	NUM
ecletica-1329	295	45	4	4	NUM
ecletica-1329	295	46	4	4	NUM
ecletica-1329	295	47	4	4	NUM
ecletica-1329	295	48	5	5	NUM
ecletica-1329	295	49	4	4	NUM
ecletica-1329	295	50	4	4	NUM
ecletica-1329	295	51	4	4	NUM
ecletica-1329	295	52	5	5	NUM
ecletica-1329	295	53	5	5	NUM
ecletica-1329	295	54	5	5	NUM
ecletica-1329	295	55	4	4	NUM
ecletica-1329	295	56	hepatotoxicity	hepatotoxicity	NOUN
ecletica-1329	295	57	–	–	PUNCT
ecletica-1329	295	58	–	–	PUNCT
ecletica-1329	295	59	–	–	PUNCT
ecletica-1329	295	60	–	–	PUNCT
ecletica-1329	295	61	–	–	PUNCT
ecletica-1329	295	62	–	–	PUNCT
ecletica-1329	295	63	–	–	PUNCT
ecletica-1329	295	64	–	–	PUNCT
ecletica-1329	295	65	–	–	PUNCT
ecletica-1329	295	66	+	+	PUNCT
ecletica-1329	296	1	+	+	PUNCT
ecletica-1329	296	2	+	+	PUNCT
ecletica-1329	296	3	+	+	CCONJ
ecletica-1329	296	4	+	+	X
ecletica-1329	296	5	–	–	PUNCT
ecletica-1329	296	6	carcinogenicity	carcinogenicity	NOUN
ecletica-1329	296	7	–	–	PUNCT
ecletica-1329	296	8	+	+	PUNCT
ecletica-1329	297	1	+	+	PUNCT
ecletica-1329	297	2	+	+	PUNCT
ecletica-1329	297	3	+	+	CCONJ
ecletica-1329	297	4	+	+	X
ecletica-1329	297	5	–	–	PUNCT
ecletica-1329	297	6	–	–	PUNCT
ecletica-1329	297	7	–	–	PUNCT
ecletica-1329	297	8	–	–	PUNCT
ecletica-1329	297	9	+	+	PUNCT
ecletica-1329	297	10	+	+	X
ecletica-1329	297	11	–	–	PUNCT
ecletica-1329	297	12	–	–	PUNCT
ecletica-1329	297	13	+	+	NUM
ecletica-1329	297	14	immunotoxicity	immunotoxicity	NOUN
ecletica-1329	297	15	–	–	PUNCT
ecletica-1329	297	16	+	+	PUNCT
ecletica-1329	298	1	+	+	PUNCT
ecletica-1329	298	2	+	+	PUNCT
ecletica-1329	298	3	+	+	PUNCT
ecletica-1329	298	4	+	+	PUNCT
ecletica-1329	298	5	+	+	CCONJ
ecletica-1329	298	6	+	+	X
ecletica-1329	298	7	–	–	PUNCT
ecletica-1329	298	8	–	–	PUNCT
ecletica-1329	298	9	+	+	PUNCT
ecletica-1329	299	1	+	+	PUNCT
ecletica-1329	299	2	+	+	CCONJ
ecletica-1329	299	3	+	+	CCONJ
ecletica-1329	299	4	–	–	PUNCT
ecletica-1329	299	5	mutagenicity	mutagenicity	NOUN
ecletica-1329	299	6	–	–	PUNCT
ecletica-1329	299	7	+	+	PUNCT
ecletica-1329	300	1	+	+	PUNCT
ecletica-1329	300	2	+	+	PUNCT
ecletica-1329	300	3	+	+	CCONJ
ecletica-1329	300	4	+	+	X
ecletica-1329	300	5	–	–	PUNCT
ecletica-1329	300	6	–	–	PUNCT
ecletica-1329	300	7	–	–	PUNCT
ecletica-1329	300	8	–	–	PUNCT
ecletica-1329	300	9	–	–	PUNCT
ecletica-1329	300	10	+	+	NUM
ecletica-1329	300	11	–	–	PUNCT
ecletica-1329	300	12	–	–	PUNCT
ecletica-1329	300	13	–	–	PUNCT
ecletica-1329	300	14	cytotoxicity	cytotoxicity	NOUN
ecletica-1329	300	15	–	–	PUNCT
ecletica-1329	300	16	–	–	PUNCT
ecletica-1329	300	17	–	–	PUNCT
ecletica-1329	300	18	–	–	PUNCT
ecletica-1329	300	19	–	–	PUNCT
ecletica-1329	300	20	–	–	PUNCT
ecletica-1329	300	21	–	–	PUNCT
ecletica-1329	300	22	–	–	PUNCT
ecletica-1329	300	23	–	–	PUNCT
ecletica-1329	300	24	–	–	PUNCT
ecletica-1329	300	25	–	–	PUNCT
ecletica-1329	300	26	–	–	PUNCT
ecletica-1329	300	27	–	–	PUNCT
ecletica-1329	300	28	+	+	NUM
ecletica-1329	300	29	–	–	PUNCT
ecletica-1329	300	30	5	5	NUM
ecletica-1329	300	31	-	-	PUNCT
ecletica-1329	300	32	flu	flu	NOUN
ecletica-1329	300	33	:	:	PUNCT
ecletica-1329	300	34	5	5	NUM
ecletica-1329	300	35	-	-	PUNCT
ecletica-1329	300	36	flurouracil	flurouracil	NOUN
ecletica-1329	300	37	.	.	PUNCT
ecletica-1329	301	1	https://revista.iq.unesp.br/index.php/ecletica	https://revista.iq.unesp.br/index.php/ecletica	PROPN
ecletica-1329	301	2	https://doi.org/10.26850/1678-4618eqj.v48.1.2023.p55-71	https://doi.org/10.26850/1678-4618eqj.v48.1.2023.p55-71	PROPN
ecletica-1329	301	3	original	original	ADJ
ecletica-1329	301	4	article	article	NOUN
ecletica-1329	301	5	revista.iq.unesp.br	revista.iq.unesp.br	VERB
ecletica-1329	301	6	68	68	NUM
ecletica-1329	301	7	eclética	eclética	PROPN
ecletica-1329	301	8	química	química	PROPN
ecletica-1329	301	9	,	,	PUNCT
ecletica-1329	301	10	vol	vol	NOUN
ecletica-1329	301	11	.	.	PROPN
ecletica-1329	301	12	48	48	NUM
ecletica-1329	301	13	,	,	PUNCT
ecletica-1329	301	14	n.	n.	NOUN
ecletica-1329	301	15	1	1	NUM
ecletica-1329	301	16	,	,	PUNCT
ecletica-1329	301	17	2023	2023	NUM
ecletica-1329	301	18	,	,	PUNCT
ecletica-1329	301	19	55	55	NUM
ecletica-1329	301	20	-	-	SYM
ecletica-1329	301	21	71	71	NUM
ecletica-1329	301	22	issn	issn	NOUN
ecletica-1329	301	23	:	:	PUNCT
ecletica-1329	301	24	1678	1678	NUM
ecletica-1329	301	25	-	-	SYM
ecletica-1329	301	26	4618	4618	NUM
ecletica-1329	301	27	doi	doi	NOUN
ecletica-1329	301	28	:	:	PUNCT
ecletica-1329	301	29	10.26850/1678	10.26850/1678	NUM
ecletica-1329	301	30	-	-	PUNCT
ecletica-1329	301	31	4618eqj.v48.1.2023.p55	4618eqj.v48.1.2023.p55	NUM
ecletica-1329	301	32	-	-	PUNCT
ecletica-1329	301	33	71	71	NUM
ecletica-1329	301	34	4	4	NUM
ecletica-1329	301	35	.	.	PUNCT
ecletica-1329	302	1	conclusions	conclusion	NOUN
ecletica-1329	302	2	fourteen	fourteen	NUM
ecletica-1329	302	3	selected	select	VERB
ecletica-1329	302	4	tetrahydroquinoline	tetrahydroquinoline	ADJ
ecletica-1329	302	5	derivatives	derivative	NOUN
ecletica-1329	302	6	having	have	VERB
ecletica-1329	302	7	pyrazole	pyrazole	NOUN
ecletica-1329	302	8	and	and	CCONJ
ecletica-1329	302	9	hydrazide	hydrazide	ADJ
ecletica-1329	302	10	moieties	moiety	NOUN
ecletica-1329	302	11	were	be	AUX
ecletica-1329	302	12	evaluated	evaluate	VERB
ecletica-1329	302	13	in	in	ADP
ecletica-1329	302	14	silico	silico	NOUN
ecletica-1329	302	15	against	against	ADP
ecletica-1329	302	16	human	human	ADJ
ecletica-1329	302	17	lung	lung	NOUN
ecletica-1329	302	18	cancer	cancer	NOUN
ecletica-1329	302	19	cell	cell	NOUN
ecletica-1329	302	20	lines	line	NOUN
ecletica-1329	302	21	a549	a549	PROPN
ecletica-1329	302	22	.	.	PUNCT
ecletica-1329	302	23	qsar	qsar	NOUN
ecletica-1329	302	24	technique	technique	NOUN
ecletica-1329	302	25	was	be	AUX
ecletica-1329	302	26	used	use	VERB
ecletica-1329	302	27	to	to	PART
ecletica-1329	302	28	build	build	VERB
ecletica-1329	302	29	a	a	DET
ecletica-1329	302	30	model	model	NOUN
ecletica-1329	302	31	found	find	VERB
ecletica-1329	302	32	to	to	PART
ecletica-1329	302	33	be	be	AUX
ecletica-1329	302	34	statistically	statistically	ADV
ecletica-1329	302	35	fit	fit	ADJ
ecletica-1329	302	36	with	with	ADP
ecletica-1329	302	37	a	a	DET
ecletica-1329	302	38	very	very	ADV
ecletica-1329	302	39	high	high	ADJ
ecletica-1329	302	40	predictive	predictive	ADJ
ecletica-1329	302	41	power	power	NOUN
ecletica-1329	302	42	and	and	CCONJ
ecletica-1329	302	43	the	the	DET
ecletica-1329	302	44	predicted	predict	VERB
ecletica-1329	302	45	bioactivity	bioactivity	NOUN
ecletica-1329	302	46	represented	represent	VERB
ecletica-1329	302	47	the	the	DET
ecletica-1329	302	48	experimental	experimental	ADJ
ecletica-1329	302	49	results	result	NOUN
ecletica-1329	302	50	well	well	ADV
ecletica-1329	302	51	.	.	PUNCT
ecletica-1329	303	1	molecular	molecular	ADJ
ecletica-1329	303	2	docking	docking	NOUN
ecletica-1329	303	3	analysis	analysis	NOUN
ecletica-1329	303	4	showed	show	VERB
ecletica-1329	303	5	that	that	SCONJ
ecletica-1329	303	6	compound	compound	NOUN
ecletica-1329	303	7	c14	c14	NOUN
ecletica-1329	303	8	demonstrated	demonstrate	VERB
ecletica-1329	303	9	the	the	DET
ecletica-1329	303	10	best	well	ADV
ecletica-1329	303	11	binding	binding	ADJ
ecletica-1329	303	12	affinity	affinity	NOUN
ecletica-1329	303	13	,	,	PUNCT
ecletica-1329	303	14	but	but	CCONJ
ecletica-1329	303	15	the	the	DET
ecletica-1329	303	16	drug	drug	NOUN
ecletica-1329	303	17	-	-	PUNCT
ecletica-1329	303	18	likeness	likeness	NOUN
ecletica-1329	303	19	,	,	PUNCT
ecletica-1329	303	20	pharmacokinetic	pharmacokinetic	ADJ
ecletica-1329	303	21	properties	property	NOUN
ecletica-1329	303	22	and	and	CCONJ
ecletica-1329	303	23	toxicity	toxicity	NOUN
ecletica-1329	303	24	profile	profile	NOUN
ecletica-1329	303	25	of	of	ADP
ecletica-1329	303	26	the	the	DET
ecletica-1329	303	27	test	test	NOUN
ecletica-1329	303	28	compounds	compound	NOUN
ecletica-1329	303	29	revealed	reveal	VERB
ecletica-1329	303	30	that	that	SCONJ
ecletica-1329	303	31	compound	compound	NOUN
ecletica-1329	303	32	c1	c1	PROPN
ecletica-1329	303	33	and	and	CCONJ
ecletica-1329	303	34	c9	c9	PROPN
ecletica-1329	303	35	are	be	AUX
ecletica-1329	303	36	better	well	ADJ
ecletica-1329	303	37	nsclc	nsclc	ADJ
ecletica-1329	303	38	therapeutic	therapeutic	ADJ
ecletica-1329	303	39	agents	agent	NOUN
ecletica-1329	303	40	because	because	SCONJ
ecletica-1329	303	41	they	they	PRON
ecletica-1329	303	42	possess	possess	VERB
ecletica-1329	303	43	better	well	ADJ
ecletica-1329	303	44	drug	drug	NOUN
ecletica-1329	303	45	-	-	PUNCT
ecletica-1329	303	46	likeness	likeness	NOUN
ecletica-1329	303	47	,	,	PUNCT
ecletica-1329	303	48	pharmacokinetic	pharmacokinetic	ADJ
ecletica-1329	303	49	,	,	PUNCT
ecletica-1329	303	50	and	and	CCONJ
ecletica-1329	303	51	toxicity	toxicity	NOUN
ecletica-1329	303	52	properties	property	NOUN
ecletica-1329	303	53	.	.	PUNCT
ecletica-1329	304	1	hence	hence	ADV
ecletica-1329	304	2	,	,	PUNCT
ecletica-1329	304	3	they	they	PRON
ecletica-1329	304	4	are	be	AUX
ecletica-1329	304	5	best	well	ADV
ecletica-1329	304	6	fit	fit	ADJ
ecletica-1329	304	7	for	for	ADP
ecletica-1329	304	8	development	development	NOUN
ecletica-1329	304	9	into	into	ADP
ecletica-1329	304	10	nsclc	nsclc	NOUN
ecletica-1329	304	11	therapeutic	therapeutic	ADJ
ecletica-1329	304	12	agents	agent	NOUN
ecletica-1329	304	13	.	.	PUNCT
ecletica-1329	305	1	in	in	ADP
ecletica-1329	305	2	addition	addition	NOUN
ecletica-1329	305	3	,	,	PUNCT
ecletica-1329	305	4	experimental	experimental	ADJ
ecletica-1329	305	5	validation	validation	NOUN
ecletica-1329	305	6	of	of	ADP
ecletica-1329	305	7	in	in	ADP
ecletica-1329	305	8	vivo	vivo	NOUN
ecletica-1329	305	9	and	and	CCONJ
ecletica-1329	305	10	in	in	ADP
ecletica-1329	305	11	vitro	vitro	X
ecletica-1329	305	12	assays	assay	NOUN
ecletica-1329	305	13	for	for	ADP
ecletica-1329	305	14	adme	adme	NOUN
ecletica-1329	305	15	traits	trait	NOUN
ecletica-1329	305	16	is	be	AUX
ecletica-1329	305	17	required	require	VERB
ecletica-1329	305	18	.	.	PUNCT
ecletica-1329	306	1	authors	author	NOUN
ecletica-1329	306	2	’	’	PART
ecletica-1329	306	3	contribution	contribution	NOUN
ecletica-1329	306	4	conceptualization	conceptualization	NOUN
ecletica-1329	306	5	:	:	PUNCT
ecletica-1329	306	6	erazua	erazua	NOUN
ecletica-1329	306	7	,	,	PUNCT
ecletica-1329	306	8	e.	e.	PROPN
ecletica-1329	306	9	a.	a.	PROPN
ecletica-1329	306	10	data	data	PROPN
ecletica-1329	306	11	curation	curation	NOUN
ecletica-1329	306	12	:	:	PUNCT
ecletica-1329	306	13	erazua	erazua	NOUN
ecletica-1329	306	14	,	,	PUNCT
ecletica-1329	306	15	e.	e.	PROPN
ecletica-1329	306	16	a.	a.	PROPN
ecletica-1329	306	17	;	;	PUNCT
ecletica-1329	306	18	oyebamiji	oyebamiji	NOUN
ecletica-1329	306	19	,	,	PUNCT
ecletica-1329	306	20	a.	a.	NOUN
ecletica-1329	306	21	k.	k.	PROPN
ecletica-1329	307	1	formal	formal	ADJ
ecletica-1329	307	2	analysis	analysis	NOUN
ecletica-1329	307	3	:	:	PUNCT
ecletica-1329	307	4	oyebamiji	oyebamiji	NOUN
ecletica-1329	307	5	,	,	PUNCT
ecletica-1329	307	6	a.	a.	PROPN
ecletica-1329	307	7	k.	k.	PROPN
ecletica-1329	307	8	funding	funding	PROPN
ecletica-1329	307	9	acquisition	acquisition	NOUN
ecletica-1329	307	10	:	:	PUNCT
ecletica-1329	307	11	not	not	PART
ecletica-1329	307	12	applicable	applicable	ADJ
ecletica-1329	307	13	.	.	PUNCT
ecletica-1329	308	1	investigation	investigation	NOUN
ecletica-1329	308	2	:	:	PUNCT
ecletica-1329	308	3	erazua	erazua	NOUN
ecletica-1329	308	4	,	,	PUNCT
ecletica-1329	308	5	e.	e.	PROPN
ecletica-1329	308	6	a.	a.	PROPN
ecletica-1329	308	7	;	;	PUNCT
ecletica-1329	308	8	oyebamiji	oyebamiji	NOUN
ecletica-1329	308	9	,	,	PUNCT
ecletica-1329	308	10	a.	a.	PROPN
ecletica-1329	308	11	k.	k.	PROPN
ecletica-1329	308	12	methodology	methodology	PROPN
ecletica-1329	308	13	:	:	PUNCT
ecletica-1329	309	1	akintelu	akintelu	ADV
ecletica-1329	309	2	,	,	PUNCT
ecletica-1329	309	3	s.	s.	PROPN
ecletica-1329	309	4	a.	a.	PROPN
ecletica-1329	309	5	;	;	PUNCT
ecletica-1329	309	6	adewole	adewole	NOUN
ecletica-1329	309	7	,	,	PUNCT
ecletica-1329	309	8	d.	d.	PROPN
ecletica-1329	309	9	p.	p.	PROPN
ecletica-1329	309	10	;	;	PUNCT
ecletica-1329	309	11	adelakun	adelakun	PROPN
ecletica-1329	309	12	a.	a.	NOUN
ecletica-1329	309	13	o.	o.	PROPN
ecletica-1329	309	14	project	project	PROPN
ecletica-1329	309	15	administration	administration	NOUN
ecletica-1329	309	16	:	:	PUNCT
ecletica-1329	309	17	adeleke	adeleke	PROPN
ecletica-1329	309	18	,	,	PUNCT
ecletica-1329	309	19	b.	b.	PROPN
ecletica-1329	309	20	b.	b.	PROPN
ecletica-1329	309	21	resources	resources	PROPN
ecletica-1329	309	22	:	:	PUNCT
ecletica-1329	309	23	erazua	erazua	NOUN
ecletica-1329	309	24	,	,	PUNCT
ecletica-1329	309	25	e.	e.	PROPN
ecletica-1329	309	26	a.	a.	PROPN
ecletica-1329	309	27	;	;	PUNCT
ecletica-1329	309	28	oyebamiji	oyebamiji	PROPN
ecletica-1329	309	29	,	,	PUNCT
ecletica-1329	309	30	a.	a.	NOUN
ecletica-1329	309	31	k.	k.	PROPN
ecletica-1329	309	32	software	software	PROPN
ecletica-1329	309	33	:	:	PUNCT
ecletica-1329	309	34	oyebamiji	oyebamiji	NOUN
ecletica-1329	309	35	,	,	PUNCT
ecletica-1329	309	36	a.	a.	PROPN
ecletica-1329	309	37	k.	k.	PROPN
ecletica-1329	309	38	;	;	PUNCT
ecletica-1329	309	39	adelakun	adelakun	PROPN
ecletica-1329	309	40	a.	a.	NOUN
ecletica-1329	309	41	o.	o.	PROPN
ecletica-1329	309	42	supervision	supervision	PROPN
ecletica-1329	309	43	:	:	PUNCT
ecletica-1329	309	44	adeleke	adeleke	PROPN
ecletica-1329	309	45	,	,	PUNCT
ecletica-1329	309	46	b.	b.	PROPN
ecletica-1329	309	47	b.	b.	PROPN
ecletica-1329	309	48	validation	validation	PROPN
ecletica-1329	309	49	:	:	PUNCT
ecletica-1329	309	50	oyebamiji	oyebamiji	NOUN
ecletica-1329	309	51	,	,	PUNCT
ecletica-1329	309	52	a.	a.	PROPN
ecletica-1329	309	53	k.	k.	PROPN
ecletica-1329	309	54	;	;	PUNCT
ecletica-1329	309	55	akintelu	akintelu	PROPN
ecletica-1329	309	56	,	,	PUNCT
ecletica-1329	309	57	s.	s.	PROPN
ecletica-1329	309	58	a.	a.	PROPN
ecletica-1329	309	59	visualization	visualization	PROPN
ecletica-1329	309	60	:	:	PUNCT
ecletica-1329	309	61	erazua	erazua	NOUN
ecletica-1329	309	62	,	,	PUNCT
ecletica-1329	309	63	e.	e.	PROPN
ecletica-1329	309	64	a.	a.	PROPN
ecletica-1329	309	65	;	;	PUNCT
ecletica-1329	309	66	adewole	adewole	NOUN
ecletica-1329	309	67	,	,	PUNCT
ecletica-1329	309	68	d.	d.	PROPN
ecletica-1329	309	69	p.	p.	PROPN
ecletica-1329	309	70	writing	writing	NOUN
ecletica-1329	309	71	–	–	PUNCT
ecletica-1329	309	72	original	original	ADJ
ecletica-1329	309	73	draft	draft	NOUN
ecletica-1329	309	74	:	:	PUNCT
ecletica-1329	309	75	erazua	erazua	NOUN
ecletica-1329	309	76	,	,	PUNCT
ecletica-1329	309	77	e.	e.	PROPN
ecletica-1329	309	78	a.	a.	PROPN
ecletica-1329	309	79	writing	writing	PROPN
ecletica-1329	309	80	–	–	PUNCT
ecletica-1329	309	81	review	review	NOUN
ecletica-1329	309	82	&	&	CCONJ
ecletica-1329	309	83	editing	editing	NOUN
ecletica-1329	309	84	:	:	PUNCT
ecletica-1329	309	85	erazua	erazua	NOUN
ecletica-1329	309	86	,	,	PUNCT
ecletica-1329	309	87	e.	e.	PROPN
ecletica-1329	309	88	a.	a.	PROPN
ecletica-1329	309	89	;	;	PUNCT
ecletica-1329	309	90	oyebamiji	oyebamiji	NOUN
ecletica-1329	309	91	,	,	PUNCT
ecletica-1329	309	92	a.	a.	PROPN
ecletica-1329	309	93	k.	k.	PROPN
ecletica-1329	309	94	data	data	PROPN
ecletica-1329	309	95	availability	availability	NOUN
ecletica-1329	309	96	statement	statement	NOUN
ecletica-1329	309	97	all	all	DET
ecletica-1329	309	98	data	datum	NOUN
ecletica-1329	309	99	sets	set	NOUN
ecletica-1329	309	100	were	be	AUX
ecletica-1329	309	101	generated	generate	VERB
ecletica-1329	309	102	or	or	CCONJ
ecletica-1329	309	103	analyzed	analyze	VERB
ecletica-1329	309	104	in	in	ADP
ecletica-1329	309	105	the	the	DET
ecletica-1329	309	106	current	current	ADJ
ecletica-1329	309	107	study	study	NOUN
ecletica-1329	309	108	funding	funding	NOUN
ecletica-1329	309	109	not	not	PART
ecletica-1329	309	110	applicable	applicable	ADJ
ecletica-1329	309	111	acknowledgments	acknowledgment	NOUN
ecletica-1329	309	112	we	we	PRON
ecletica-1329	309	113	are	be	AUX
ecletica-1329	309	114	grateful	grateful	ADJ
ecletica-1329	309	115	to	to	ADP
ecletica-1329	309	116	computational	computational	ADJ
ecletica-1329	309	117	chemistry	chemistry	NOUN
ecletica-1329	309	118	research	research	NOUN
ecletica-1329	309	119	laboratory	laboratory	NOUN
ecletica-1329	309	120	,	,	PUNCT
ecletica-1329	309	121	department	department	NOUN
ecletica-1329	309	122	of	of	ADP
ecletica-1329	309	123	chemistry	chemistry	NOUN
ecletica-1329	309	124	,	,	PUNCT
ecletica-1329	309	125	university	university	NOUN
ecletica-1329	309	126	of	of	ADP
ecletica-1329	309	127	ibadan	ibadan	PROPN
ecletica-1329	309	128	and	and	CCONJ
ecletica-1329	309	129	mrs	mrs	PROPN
ecletica-1329	309	130	.	.	PROPN
ecletica-1329	309	131	e.	e.	PROPN
ecletica-1329	309	132	t.	t.	PROPN
ecletica-1329	309	133	oyebamiji	oyebamiji	PROPN
ecletica-1329	309	134	as	as	ADV
ecletica-1329	309	135	well	well	ADV
ecletica-1329	309	136	as	as	ADP
ecletica-1329	309	137	miss	miss	PROPN
ecletica-1329	309	138	priscilla	priscilla	PROPN
ecletica-1329	309	139	f.	f.	PROPN
ecletica-1329	309	140	oyebamiji	oyebamiji	PROPN
ecletica-1329	309	141	for	for	ADP
ecletica-1329	309	142	the	the	DET
ecletica-1329	309	143	assistance	assistance	NOUN
ecletica-1329	309	144	in	in	ADP
ecletica-1329	309	145	the	the	DET
ecletica-1329	309	146	course	course	NOUN
ecletica-1329	309	147	of	of	ADP
ecletica-1329	309	148	this	this	DET
ecletica-1329	309	149	study	study	NOUN
ecletica-1329	309	150	.	.	PUNCT
ecletica-1329	310	1	references	reference	NOUN
ecletica-1329	310	2	adepoju	adepoju	PROPN
ecletica-1329	310	3	,	,	PUNCT
ecletica-1329	310	4	a.	a.	PROPN
ecletica-1329	310	5	j.	j.	PROPN
ecletica-1329	310	6	;	;	PUNCT
ecletica-1329	310	7	latona	latona	PROPN
ecletica-1329	310	8	,	,	PUNCT
ecletica-1329	310	9	d.	d.	PROPN
ecletica-1329	310	10	f.	f.	PROPN
ecletica-1329	310	11	;	;	PUNCT
ecletica-1329	310	12	olafare	olafare	NOUN
ecletica-1329	310	13	,	,	PUNCT
ecletica-1329	310	14	o.	o.	PROPN
ecletica-1329	310	15	g.	g.	PROPN
ecletica-1329	310	16	;	;	PUNCT
ecletica-1329	310	17	oyebamiji	oyebamiji	PROPN
ecletica-1329	310	18	,	,	PUNCT
ecletica-1329	310	19	a.	a.	PROPN
ecletica-1329	310	20	k.	k.	PROPN
ecletica-1329	310	21	;	;	PUNCT
ecletica-1329	310	22	abdul	abdul	PROPN
ecletica-1329	310	23	-	-	PUNCT
ecletica-1329	310	24	hammed	ham	VERB
ecletica-1329	310	25	,	,	PUNCT
ecletica-1329	310	26	m.	m.	NOUN
ecletica-1329	310	27	;	;	PUNCT
ecletica-1329	310	28	semire	semire	NOUN
ecletica-1329	310	29	,	,	PUNCT
ecletica-1329	310	30	b.	b.	PROPN
ecletica-1329	310	31	molecular	molecular	ADJ
ecletica-1329	310	32	docking	docking	NOUN
ecletica-1329	310	33	and	and	CCONJ
ecletica-1329	310	34	pharmacokinetics	pharmacokinetic	NOUN
ecletica-1329	310	35	studies	study	NOUN
ecletica-1329	310	36	of	of	ADP
ecletica-1329	310	37	curcuma	curcuma	PROPN
ecletica-1329	310	38	longa	longa	NOUN
ecletica-1329	310	39	(	(	PUNCT
ecletica-1329	310	40	curcumin	curcumin	NOUN
ecletica-1329	310	41	)	)	PUNCT
ecletica-1329	310	42	potency	potency	NOUN
ecletica-1329	310	43	against	against	ADP
ecletica-1329	310	44	ebola	ebola	PROPN
ecletica-1329	310	45	virus	virus	NOUN
ecletica-1329	310	46	.	.	PUNCT
ecletica-1329	311	1	ovidius	ovidius	PROPN
ecletica-1329	311	2	university	university	NOUN
ecletica-1329	311	3	annals	annals	NOUN
ecletica-1329	311	4	of	of	ADP
ecletica-1329	311	5	chemistry	chemistry	NOUN
ecletica-1329	311	6	2022	2022	NUM
ecletica-1329	311	7	,	,	PUNCT
ecletica-1329	311	8	33	33	NUM
ecletica-1329	311	9	(	(	PUNCT
ecletica-1329	311	10	1	1	NUM
ecletica-1329	311	11	)	)	PUNCT
ecletica-1329	311	12	,	,	PUNCT
ecletica-1329	311	13	23–35	23–35	NUM
ecletica-1329	311	14	.	.	PUNCT
ecletica-1329	311	15	https://doi.org/10.2478/auoc2022-0004	https://doi.org/10.2478/auoc2022-0004	PROPN
ecletica-1329	311	16	banerjee	banerjee	NOUN
ecletica-1329	311	17	,	,	PUNCT
ecletica-1329	311	18	p.	p.	PROPN
ecletica-1329	311	19	;	;	PUNCT
ecletica-1329	311	20	eckert	eckert	PROPN
ecletica-1329	311	21	,	,	PUNCT
ecletica-1329	311	22	a.	a.	PROPN
ecletica-1329	311	23	o.	o.	PROPN
ecletica-1329	311	24	;	;	PUNCT
ecletica-1329	311	25	schrey	schrey	PROPN
ecletica-1329	311	26	,	,	PUNCT
ecletica-1329	311	27	a.	a.	PROPN
ecletica-1329	311	28	k.	k.	PROPN
ecletica-1329	311	29	;	;	PUNCT
ecletica-1329	311	30	preissner	preissner	PROPN
ecletica-1329	311	31	,	,	PUNCT
ecletica-1329	311	32	r.	r.	PROPN
ecletica-1329	311	33	protox	protox	PROPN
ecletica-1329	311	34	-	-	PUNCT
ecletica-1329	311	35	ii	ii	PROPN
ecletica-1329	311	36	:	:	PUNCT
ecletica-1329	311	37	a	a	DET
ecletica-1329	311	38	webserver	webserver	NOUN
ecletica-1329	311	39	for	for	ADP
ecletica-1329	311	40	the	the	DET
ecletica-1329	311	41	prediction	prediction	NOUN
ecletica-1329	311	42	of	of	ADP
ecletica-1329	311	43	toxicity	toxicity	NOUN
ecletica-1329	311	44	of	of	ADP
ecletica-1329	311	45	chemicals	chemical	NOUN
ecletica-1329	311	46	.	.	PUNCT
ecletica-1329	312	1	nucleic	nucleic	ADJ
ecletica-1329	312	2	acids	acid	NOUN
ecletica-1329	312	3	res	re	NOUN
ecletica-1329	312	4	.	.	PROPN
ecletica-1329	312	5	2018	2018	NUM
ecletica-1329	312	6	,	,	PUNCT
ecletica-1329	312	7	46	46	NUM
ecletica-1329	312	8	(	(	PUNCT
ecletica-1329	312	9	w1	w1	NOUN
ecletica-1329	312	10	)	)	PUNCT
ecletica-1329	312	11	,	,	PUNCT
ecletica-1329	312	12	w257	w257	PROPN
ecletica-1329	312	13	–	–	PUNCT
ecletica-1329	312	14	w263	w263	NUM
ecletica-1329	312	15	.	.	PUNCT
ecletica-1329	313	1	https://doi.org/10.1093/nar/gky318	https://doi.org/10.1093/nar/gky318	PROPN
ecletica-1329	313	2	becke	becke	NOUN
ecletica-1329	313	3	,	,	PUNCT
ecletica-1329	313	4	a.	a.	PROPN
ecletica-1329	313	5	d.	d.	PROPN
ecletica-1329	313	6	density	density	PROPN
ecletica-1329	313	7	-	-	PUNCT
ecletica-1329	313	8	functional	functional	ADJ
ecletica-1329	313	9	thermochemistry	thermochemistry	NOUN
ecletica-1329	313	10	.	.	PUNCT
ecletica-1329	314	1	iii	iii	X
ecletica-1329	314	2	.	.	PUNCT
ecletica-1329	315	1	the	the	DET
ecletica-1329	315	2	role	role	NOUN
ecletica-1329	315	3	of	of	ADP
ecletica-1329	315	4	exact	exact	ADJ
ecletica-1329	315	5	exchange	exchange	NOUN
ecletica-1329	315	6	.	.	PUNCT
ecletica-1329	316	1	j.	j.	PROPN
ecletica-1329	316	2	chem	chem	PROPN
ecletica-1329	316	3	.	.	PUNCT
ecletica-1329	317	1	phys	phy	NOUN
ecletica-1329	317	2	.	.	PUNCT
ecletica-1329	318	1	1993	1993	NUM
ecletica-1329	318	2	,	,	PUNCT
ecletica-1329	318	3	98	98	NUM
ecletica-1329	318	4	(	(	PUNCT
ecletica-1329	318	5	7	7	NUM
ecletica-1329	318	6	)	)	PUNCT
ecletica-1329	318	7	,	,	PUNCT
ecletica-1329	318	8	5648	5648	NUM
ecletica-1329	318	9	.	.	PUNCT
ecletica-1329	319	1	https://doi.org/10.1063/1.464913	https://doi.org/10.1063/1.464913	PROPN
ecletica-1329	319	2	beheshti	beheshti	PROPN
ecletica-1329	319	3	,	,	PUNCT
ecletica-1329	319	4	j.	j.	PROPN
ecletica-1329	319	5	;	;	PUNCT
ecletica-1329	319	6	bilal	bilal	PROPN
ecletica-1329	319	7	,	,	PUNCT
ecletica-1329	319	8	d.	d.	PROPN
ecletica-1329	319	9	;	;	PUNCT
ecletica-1329	319	10	mackey	mackey	PROPN
ecletica-1329	319	11	,	,	PUNCT
ecletica-1329	319	12	t.	t.	PROPN
ecletica-1329	319	13	p.	p.	PROPN
ecletica-1329	319	14	;	;	PUNCT
ecletica-1329	319	15	limberg	limberg	PROPN
ecletica-1329	319	16	,	,	PUNCT
ecletica-1329	319	17	l.	l.	PROPN
ecletica-1329	319	18	;	;	PUNCT
ecletica-1329	319	19	bartlett	bartlett	PROPN
ecletica-1329	319	20	,	,	PUNCT
ecletica-1329	319	21	j.	j.	PROPN
ecletica-1329	319	22	c.	c.	PROPN
ecletica-1329	319	23	;	;	PUNCT
ecletica-1329	319	24	gwizdka	gwizdka	PROPN
ecletica-1329	319	25	,	,	PUNCT
ecletica-1329	319	26	j.	j.	PROPN
ecletica-1329	319	27	;	;	PUNCT
ecletica-1329	319	28	jocobson	jocobson	NOUN
ecletica-1329	319	29	,	,	PUNCT
ecletica-1329	319	30	t.	t.	PROPN
ecletica-1329	319	31	;	;	PUNCT
ecletica-1329	319	32	ishimura	ishimura	NOUN
ecletica-1329	319	33	,	,	PUNCT
ecletica-1329	319	34	y.	y.	PROPN
ecletica-1329	319	35	information	information	NOUN
ecletica-1329	319	36	literacy	literacy	NOUN
ecletica-1329	319	37	:	:	PUNCT
ecletica-1329	319	38	bridging	bridge	VERB
ecletica-1329	319	39	the	the	DET
ecletica-1329	319	40	gap	gap	NOUN
ecletica-1329	319	41	between	between	ADP
ecletica-1329	319	42	theory	theory	NOUN
ecletica-1329	319	43	and	and	CCONJ
ecletica-1329	319	44	practice	practice	NOUN
ecletica-1329	319	45	.	.	PUNCT
ecletica-1329	320	1	proceedings	proceeding	NOUN
ecletica-1329	320	2	of	of	ADP
ecletica-1329	320	3	the	the	DET
ecletica-1329	320	4	association	association	NOUN
ecletica-1329	320	5	for	for	ADP
ecletica-1329	320	6	information	information	NOUN
ecletica-1329	320	7	science	science	NOUN
ecletica-1329	320	8	and	and	CCONJ
ecletica-1329	320	9	technology	technology	NOUN
ecletica-1329	320	10	,	,	PUNCT
ecletica-1329	320	11	2016	2016	NUM
ecletica-1329	320	12	,	,	PUNCT
ecletica-1329	320	13	53	53	NUM
ecletica-1329	320	14	(	(	PUNCT
ecletica-1329	320	15	1	1	NUM
ecletica-1329	320	16	)	)	PUNCT
ecletica-1329	320	17	,	,	PUNCT
ecletica-1329	320	18	1–6	1–6	X
ecletica-1329	320	19	.	.	PUNCT
ecletica-1329	321	1	https://doi.org/10.1002/pra2.2016.14505301019	https://doi.org/10.1002/pra2.2016.14505301019	PROPN
ecletica-1329	321	2	capra	capra	PROPN
ecletica-1329	321	3	,	,	PUNCT
ecletica-1329	321	4	j.	j.	PROPN
ecletica-1329	321	5	a.	a.	PROPN
ecletica-1329	321	6	;	;	PUNCT
ecletica-1329	321	7	laskowski	laskowski	PROPN
ecletica-1329	321	8	,	,	PUNCT
ecletica-1329	321	9	r.	r.	PROPN
ecletica-1329	321	10	a.	a.	PROPN
ecletica-1329	321	11	;	;	PUNCT
ecletica-1329	321	12	thornton	thornton	PROPN
ecletica-1329	321	13	,	,	PUNCT
ecletica-1329	321	14	j.	j.	PROPN
ecletica-1329	321	15	m.	m.	PROPN
ecletica-1329	321	16	;	;	PUNCT
ecletica-1329	321	17	singh	singh	PROPN
ecletica-1329	321	18	,	,	PUNCT
ecletica-1329	321	19	m.	m.	NOUN
ecletica-1329	321	20	;	;	PUNCT
ecletica-1329	321	21	funkhouser	funkhouser	NOUN
ecletica-1329	321	22	,	,	PUNCT
ecletica-1329	321	23	t.	t.	NOUN
ecletica-1329	321	24	a.	a.	NOUN
ecletica-1329	321	25	predicting	predict	VERB
ecletica-1329	321	26	protein	protein	NOUN
ecletica-1329	321	27	ligand	ligand	NOUN
ecletica-1329	321	28	binding	bind	VERB
ecletica-1329	321	29	sites	site	NOUN
ecletica-1329	321	30	by	by	ADP
ecletica-1329	321	31	combining	combine	VERB
ecletica-1329	321	32	evolutionary	evolutionary	ADJ
ecletica-1329	321	33	sequence	sequence	NOUN
ecletica-1329	321	34	conservation	conservation	NOUN
ecletica-1329	321	35	and	and	CCONJ
ecletica-1329	321	36	3d	3d	NUM
ecletica-1329	321	37	structure	structure	NOUN
ecletica-1329	321	38	.	.	PUNCT
ecletica-1329	322	1	plos	plos	PROPN
ecletica-1329	322	2	comput	comput	PROPN
ecletica-1329	322	3	.	.	PUNCT
ecletica-1329	323	1	biol	biol	PROPN
ecletica-1329	323	2	.	.	PUNCT
ecletica-1329	324	1	2009	2009	NUM
ecletica-1329	324	2	,	,	PUNCT
ecletica-1329	324	3	5	5	NUM
ecletica-1329	324	4	(	(	PUNCT
ecletica-1329	324	5	12	12	NUM
ecletica-1329	324	6	)	)	PUNCT
ecletica-1329	324	7	,	,	PUNCT
ecletica-1329	324	8	1000585	1000585	NUM
ecletica-1329	324	9	.	.	PUNCT
ecletica-1329	325	1	https://doi.org/10.1371/journal.pcbi.1000585	https://doi.org/10.1371/journal.pcbi.1000585	PROPN
ecletica-1329	325	2	cassidy	cassidy	PROPN
ecletica-1329	325	3	,	,	PUNCT
ecletica-1329	325	4	a.	a.	PROPN
ecletica-1329	325	5	;	;	PUNCT
ecletica-1329	325	6	myles	myles	PROPN
ecletica-1329	325	7	,	,	PUNCT
ecletica-1329	325	8	j.	j.	PROPN
ecletica-1329	325	9	p.	p.	PROPN
ecletica-1329	325	10	;	;	PUNCT
ecletica-1329	325	11	van	van	PROPN
ecletica-1329	325	12	tongeren	tongeren	NOUN
ecletica-1329	325	13	,	,	PUNCT
ecletica-1329	325	14	m.	m.	NOUN
ecletica-1329	325	15	;	;	PUNCT
ecletica-1329	325	16	page	page	NOUN
ecletica-1329	325	17	,	,	PUNCT
ecletica-1329	325	18	r.	r.	PROPN
ecletica-1329	325	19	d.	d.	PROPN
ecletica-1329	325	20	;	;	PUNCT
ecletica-1329	325	21	liloglou	liloglou	PROPN
ecletica-1329	325	22	,	,	PUNCT
ecletica-1329	325	23	t.	t.	PROPN
ecletica-1329	325	24	;	;	PUNCT
ecletica-1329	325	25	duffy	duffy	PROPN
ecletica-1329	325	26	,	,	PUNCT
ecletica-1329	325	27	s.	s.	PROPN
ecletica-1329	325	28	w.	w.	PROPN
ecletica-1329	325	29	;	;	PUNCT
ecletica-1329	325	30	field	field	NOUN
ecletica-1329	325	31	,	,	PUNCT
ecletica-1329	325	32	j.	j.	PROPN
ecletica-1329	325	33	k.	k.	PROPN
ecletica-1329	326	1	the	the	DET
ecletica-1329	326	2	llp	llp	PROPN
ecletica-1329	326	3	risk	risk	NOUN
ecletica-1329	326	4	model	model	PROPN
ecletica-1329	326	5	:	:	PUNCT
ecletica-1329	326	6	an	an	DET
ecletica-1329	326	7	individual	individual	ADJ
ecletica-1329	326	8	risk	risk	NOUN
ecletica-1329	326	9	prediction	prediction	NOUN
ecletica-1329	326	10	model	model	NOUN
ecletica-1329	326	11	for	for	ADP
ecletica-1329	326	12	lung	lung	NOUN
ecletica-1329	326	13	cancer	cancer	NOUN
ecletica-1329	326	14	,	,	PUNCT
ecletica-1329	326	15	br	br	PROPN
ecletica-1329	326	16	.	.	PUNCT
ecletica-1329	327	1	j.	j.	PROPN
ecletica-1329	327	2	cancer	cancer	PROPN
ecletica-1329	327	3	2008	2008	NUM
ecletica-1329	327	4	,	,	PUNCT
ecletica-1329	327	5	98	98	NUM
ecletica-1329	327	6	(	(	PUNCT
ecletica-1329	327	7	2	2	NUM
ecletica-1329	327	8	)	)	PUNCT
ecletica-1329	327	9	,	,	PUNCT
ecletica-1329	327	10	270–276	270–276	NUM
ecletica-1329	327	11	.	.	PUNCT
ecletica-1329	328	1	https://doi.org/10.1038/sj.bjc.6604158	https://doi.org/10.1038/sj.bjc.6604158	PROPN
ecletica-1329	328	2	cheng	cheng	PROPN
ecletica-1329	328	3	,	,	PUNCT
ecletica-1329	328	4	a.	a.	PROPN
ecletica-1329	328	5	;	;	PUNCT
ecletica-1329	328	6	dixon	dixon	PROPN
ecletica-1329	328	7	,	,	PUNCT
ecletica-1329	328	8	s.	s.	PROPN
ecletica-1329	328	9	l.	l.	PROPN
ecletica-1329	328	10	in	in	ADP
ecletica-1329	328	11	silico	silico	NOUN
ecletica-1329	328	12	models	model	NOUN
ecletica-1329	328	13	for	for	ADP
ecletica-1329	328	14	the	the	DET
ecletica-1329	328	15	prediction	prediction	NOUN
ecletica-1329	328	16	of	of	ADP
ecletica-1329	328	17	dose	dose	NOUN
ecletica-1329	328	18	-	-	PUNCT
ecletica-1329	328	19	dependent	dependent	ADJ
ecletica-1329	328	20	human	human	ADJ
ecletica-1329	328	21	hepatotoxicity	hepatotoxicity	NOUN
ecletica-1329	328	22	.	.	PUNCT
ecletica-1329	329	1	j.	j.	PROPN
ecletica-1329	329	2	comput	comput	PROPN
ecletica-1329	329	3	.	.	PUNCT
ecletica-1329	329	4	aided	aid	VERB
ecletica-1329	329	5	mol	mol	PROPN
ecletica-1329	329	6	.	.	PUNCT
ecletica-1329	330	1	des	des	PROPN
ecletica-1329	330	2	.	.	PROPN
ecletica-1329	330	3	2003	2003	NUM
ecletica-1329	330	4	,	,	PUNCT
ecletica-1329	330	5	17	17	NUM
ecletica-1329	330	6	(	(	PUNCT
ecletica-1329	330	7	12	12	NUM
ecletica-1329	330	8	)	)	PUNCT
ecletica-1329	330	9	,	,	PUNCT
ecletica-1329	330	10	811–823	811–823	NUM
ecletica-1329	330	11	.	.	PUNCT
ecletica-1329	331	1	https://doi.org/10.1023/b:jcam.0000021834.50768.c6	https://doi.org/10.1023/b:jcam.0000021834.50768.c6	PROPN
ecletica-1329	331	2	collins	collins	PROPN
ecletica-1329	331	3	,	,	PUNCT
ecletica-1329	331	4	l.	l.	PROPN
ecletica-1329	331	5	g.	g.	PROPN
ecletica-1329	331	6	;	;	PUNCT
ecletica-1329	331	7	haines	haine	NOUN
ecletica-1329	331	8	,	,	PUNCT
ecletica-1329	331	9	c.	c.	PROPN
ecletica-1329	331	10	;	;	PUNCT
ecletica-1329	331	11	perkel	perkel	PROPN
ecletica-1329	331	12	,	,	PUNCT
ecletica-1329	331	13	r.	r.	PROPN
ecletica-1329	331	14	;	;	PUNCT
ecletica-1329	331	15	enck	enck	ADV
ecletica-1329	331	16	,	,	PUNCT
ecletica-1329	331	17	r.	r.	PROPN
ecletica-1329	331	18	e.	e.	PROPN
ecletica-1329	331	19	lung	lung	PROPN
ecletica-1329	331	20	cancer	cancer	NOUN
ecletica-1329	331	21	:	:	PUNCT
ecletica-1329	331	22	diagnosis	diagnosis	NOUN
ecletica-1329	331	23	and	and	CCONJ
ecletica-1329	331	24	management	management	NOUN
ecletica-1329	331	25	.	.	PUNCT
ecletica-1329	332	1	am	be	AUX
ecletica-1329	332	2	.	.	PUNCT
ecletica-1329	333	1	fam	fam	PROPN
ecletica-1329	333	2	.	.	PUNCT
ecletica-1329	333	3	physician	physician	PROPN
ecletica-1329	333	4	.	.	PUNCT
ecletica-1329	334	1	2007	2007	NUM
ecletica-1329	334	2	,	,	PUNCT
ecletica-1329	334	3	75	75	NUM
ecletica-1329	334	4	(	(	PUNCT
ecletica-1329	334	5	1	1	NUM
ecletica-1329	334	6	)	)	PUNCT
ecletica-1329	334	7	,	,	PUNCT
ecletica-1329	334	8	56–63	56–63	NUM
ecletica-1329	334	9	.	.	PUNCT
ecletica-1329	335	1	daina	daina	PROPN
ecletica-1329	335	2	,	,	PUNCT
ecletica-1329	335	3	a.	a.	PROPN
ecletica-1329	335	4	;	;	PUNCT
ecletica-1329	335	5	michielin	michielin	PROPN
ecletica-1329	335	6	,	,	PUNCT
ecletica-1329	335	7	o.	o.	PROPN
ecletica-1329	335	8	;	;	PUNCT
ecletica-1329	335	9	zoete	zoete	NOUN
ecletica-1329	335	10	,	,	PUNCT
ecletica-1329	335	11	v.	v.	ADP
ecletica-1329	335	12	swissadme	swissadme	PROPN
ecletica-1329	335	13	:	:	PUNCT
ecletica-1329	335	14	a	a	DET
ecletica-1329	335	15	free	free	ADJ
ecletica-1329	335	16	web	web	NOUN
ecletica-1329	335	17	tool	tool	NOUN
ecletica-1329	335	18	to	to	PART
ecletica-1329	335	19	evaluate	evaluate	VERB
ecletica-1329	335	20	pharmacokinetics	pharmacokinetic	NOUN
ecletica-1329	335	21	,	,	PUNCT
ecletica-1329	335	22	drug	drug	NOUN
ecletica-1329	335	23	-	-	PUNCT
ecletica-1329	335	24	likeness	likeness	NOUN
ecletica-1329	335	25	and	and	CCONJ
ecletica-1329	335	26	medicinal	medicinal	ADJ
ecletica-1329	335	27	chemistry	chemistry	NOUN
ecletica-1329	335	28	friendliness	friendliness	NOUN
ecletica-1329	335	29	of	of	ADP
ecletica-1329	335	30	small	small	ADJ
ecletica-1329	335	31	molecules	molecule	NOUN
ecletica-1329	335	32	.	.	PUNCT
ecletica-1329	336	1	sci	sci	PROPN
ecletica-1329	336	2	.	.	PROPN
ecletica-1329	336	3	rep	rep	PROPN
ecletica-1329	336	4	.	.	PROPN
ecletica-1329	336	5	2017	2017	NUM
ecletica-1329	336	6	,	,	PUNCT
ecletica-1329	336	7	7	7	NUM
ecletica-1329	336	8	,	,	PUNCT
ecletica-1329	336	9	42717	42717	NUM
ecletica-1329	336	10	.	.	PUNCT
ecletica-1329	337	1	https://doi.org/10.1038/srep42717	https://doi.org/10.1038/srep42717	PROPN
ecletica-1329	337	2	darvas	darvas	PROPN
ecletica-1329	337	3	,	,	PUNCT
ecletica-1329	337	4	f.	f.	PROPN
ecletica-1329	337	5	;	;	PUNCT
ecletica-1329	337	6	keseru	keseru	PROPN
ecletica-1329	337	7	,	,	PUNCT
ecletica-1329	337	8	g.	g.	PROPN
ecletica-1329	337	9	;	;	PUNCT
ecletica-1329	337	10	papp	papp	PROPN
ecletica-1329	337	11	,	,	PUNCT
ecletica-1329	337	12	a.	a.	NOUN
ecletica-1329	337	13	;	;	PUNCT
ecletica-1329	337	14	dorman	dorman	PROPN
ecletica-1329	337	15	,	,	PUNCT
ecletica-1329	337	16	g.	g.	PROPN
ecletica-1329	337	17	;	;	PUNCT
ecletica-1329	337	18	urge	urge	NOUN
ecletica-1329	337	19	,	,	PUNCT
ecletica-1329	337	20	l.	l.	PROPN
ecletica-1329	337	21	;	;	PUNCT
ecletica-1329	337	22	krajcsi	krajcsi	PROPN
ecletica-1329	337	23	,	,	PUNCT
ecletica-1329	337	24	p.	p.	NOUN
ecletica-1329	337	25	in	in	ADP
ecletica-1329	337	26	silico	silico	NOUN
ecletica-1329	337	27	and	and	CCONJ
ecletica-1329	337	28	ex	ex	PRON
ecletica-1329	337	29	silico	silico	NOUN
ecletica-1329	337	30	adme	adme	NOUN
ecletica-1329	337	31	approaches	approach	VERB
ecletica-1329	337	32	for	for	ADP
ecletica-1329	337	33	drug	drug	NOUN
ecletica-1329	337	34	discovery	discovery	NOUN
ecletica-1329	337	35	.	.	PUNCT
ecletica-1329	338	1	curr	curr	PROPN
ecletica-1329	338	2	.	.	PUNCT
ecletica-1329	339	1	top	top	PROPN
ecletica-1329	339	2	.	.	PUNCT
ecletica-1329	340	1	med	med	PROPN
ecletica-1329	340	2	.	.	PROPN
ecletica-1329	340	3	chem	chem	PROPN
ecletica-1329	340	4	.	.	PUNCT
ecletica-1329	341	1	2002	2002	NUM
ecletica-1329	341	2	,	,	PUNCT
ecletica-1329	341	3	2	2	NUM
ecletica-1329	341	4	(	(	PUNCT
ecletica-1329	341	5	12	12	NUM
ecletica-1329	341	6	)	)	PUNCT
ecletica-1329	341	7	,	,	PUNCT
ecletica-1329	341	8	1287–1304	1287–1304	NUM
ecletica-1329	341	9	.	.	PUNCT
ecletica-1329	341	10	https://doi.org/10.2174/1568026023392841	https://doi.org/10.2174/1568026023392841	PROPN
ecletica-1329	342	1	https://revista.iq.unesp.br/index.php/ecletica	https://revista.iq.unesp.br/index.php/ecletica	PROPN
ecletica-1329	342	2	https://doi.org/10.26850/1678-4618eqj.v48.1.2023.p55-71	https://doi.org/10.26850/1678-4618eqj.v48.1.2023.p55-71	PROPN
ecletica-1329	342	3	https://doi.org/10.2478/auoc-2022-0004	https://doi.org/10.2478/auoc-2022-0004	PROPN
ecletica-1329	342	4	https://doi.org/10.2478/auoc-2022-0004	https://doi.org/10.2478/auoc-2022-0004	ADJ
ecletica-1329	342	5	https://doi.org/10.2478/auoc-2022-0004	https://doi.org/10.2478/auoc-2022-0004	ADJ
ecletica-1329	342	6	https://doi.org/10.2478/auoc-2022-0004	https://doi.org/10.2478/auoc-2022-0004	ADJ
ecletica-1329	342	7	https://doi.org/10.2478/auoc-2022-0004	https://doi.org/10.2478/auoc-2022-0004	PROPN
ecletica-1329	342	8	https://doi.org/10.2478/auoc-2022-0004	https://doi.org/10.2478/auoc-2022-0004	PROPN
ecletica-1329	342	9	https://doi.org/10.1093/nar/gky318	https://doi.org/10.1093/nar/gky318	PROPN
ecletica-1329	342	10	https://doi.org/10.1093/nar/gky318	https://doi.org/10.1093/nar/gky318	PROPN
ecletica-1329	342	11	https://doi.org/10.1093/nar/gky318	https://doi.org/10.1093/nar/gky318	PROPN
ecletica-1329	342	12	https://doi.org/10.1093/nar/gky318	https://doi.org/10.1093/nar/gky318	PROPN
ecletica-1329	342	13	https://doi.org/10.1063/1.464913	https://doi.org/10.1063/1.464913	NOUN
ecletica-1329	342	14	https://doi.org/10.1063/1.464913	https://doi.org/10.1063/1.464913	PROPN
ecletica-1329	342	15	https://doi.org/10.1063/1.464913	https://doi.org/10.1063/1.464913	NOUN
ecletica-1329	342	16	https://doi.org/10.1002/pra2.2016.14505301019	https://doi.org/10.1002/pra2.2016.14505301019	VERB
ecletica-1329	342	17	https://doi.org/10.1002/pra2.2016.14505301019	https://doi.org/10.1002/pra2.2016.14505301019	PROPN
ecletica-1329	342	18	https://doi.org/10.1002/pra2.2016.14505301019	https://doi.org/10.1002/pra2.2016.14505301019	PROPN
ecletica-1329	342	19	https://doi.org/10.1002/pra2.2016.14505301019	https://doi.org/10.1002/pra2.2016.14505301019	PROPN
ecletica-1329	342	20	https://doi.org/10.1002/pra2.2016.14505301019	https://doi.org/10.1002/pra2.2016.14505301019	PROPN
ecletica-1329	342	21	https://doi.org/10.1002/pra2.2016.14505301019	https://doi.org/10.1002/pra2.2016.14505301019	PROPN
ecletica-1329	342	22	https://doi.org/10.1371/journal.pcbi.1000585	https://doi.org/10.1371/journal.pcbi.1000585	PROPN
ecletica-1329	342	23	https://doi.org/10.1371/journal.pcbi.1000585	https://doi.org/10.1371/journal.pcbi.1000585	PROPN
ecletica-1329	342	24	https://doi.org/10.1371/journal.pcbi.1000585	https://doi.org/10.1371/journal.pcbi.1000585	PROPN
ecletica-1329	342	25	https://doi.org/10.1371/journal.pcbi.1000585	https://doi.org/10.1371/journal.pcbi.1000585	PROPN
ecletica-1329	342	26	https://doi.org/10.1371/journal.pcbi.1000585	https://doi.org/10.1371/journal.pcbi.1000585	PROPN
ecletica-1329	342	27	https://doi.org/10.1038/sj.bjc.6604158	https://doi.org/10.1038/sj.bjc.6604158	PROPN
ecletica-1329	342	28	https://doi.org/10.1038/sj.bjc.6604158	https://doi.org/10.1038/sj.bjc.6604158	PROPN
ecletica-1329	342	29	https://doi.org/10.1038/sj.bjc.6604158	https://doi.org/10.1038/sj.bjc.6604158	PROPN
ecletica-1329	342	30	https://doi.org/10.1038/sj.bjc.6604158	https://doi.org/10.1038/sj.bjc.6604158	PROPN
ecletica-1329	342	31	https://doi.org/10.1038/sj.bjc.6604158	https://doi.org/10.1038/sj.bjc.6604158	PROPN
ecletica-1329	342	32	https://doi.org/10.1023/b:jcam.0000021834.50768.c6	https://doi.org/10.1023/b:jcam.0000021834.50768.c6	PROPN
ecletica-1329	342	33	https://doi.org/10.1023/b:jcam.0000021834.50768.c6	https://doi.org/10.1023/b:jcam.0000021834.50768.c6	PROPN
ecletica-1329	342	34	https://doi.org/10.1023/b:jcam.0000021834.50768.c6	https://doi.org/10.1023/b:jcam.0000021834.50768.c6	PROPN
ecletica-1329	342	35	https://doi.org/10.1023/b:jcam.0000021834.50768.c6	https://doi.org/10.1023/b:jcam.0000021834.50768.c6	PROPN
ecletica-1329	342	36	https://doi.org/10.1038/srep42717	https://doi.org/10.1038/srep42717	PROPN
ecletica-1329	342	37	https://doi.org/10.1038/srep42717	https://doi.org/10.1038/srep42717	PROPN
ecletica-1329	342	38	https://doi.org/10.1038/srep42717	https://doi.org/10.1038/srep42717	PROPN
ecletica-1329	342	39	https://doi.org/10.1038/srep42717	https://doi.org/10.1038/srep42717	PROPN
ecletica-1329	342	40	https://doi.org/10.2174/1568026023392841	https://doi.org/10.2174/1568026023392841	PROPN
ecletica-1329	342	41	https://doi.org/10.2174/1568026023392841	https://doi.org/10.2174/1568026023392841	PROPN
ecletica-1329	342	42	https://doi.org/10.2174/1568026023392841	https://doi.org/10.2174/1568026023392841	PROPN
ecletica-1329	343	1	https://doi.org/10.2174/1568026023392841	https://doi.org/10.2174/1568026023392841	PUNCT
ecletica-1329	343	2	original	original	ADJ
ecletica-1329	343	3	article	article	NOUN
ecletica-1329	343	4	revista.iq.unesp.br	revista.iq.unesp.br	PROPN
ecletica-1329	343	5	69	69	NUM
ecletica-1329	343	6	eclética	eclética	NOUN
ecletica-1329	343	7	química	química	PROPN
ecletica-1329	343	8	,	,	PUNCT
ecletica-1329	343	9	vol	vol	NOUN
ecletica-1329	343	10	.	.	PROPN
ecletica-1329	343	11	48	48	NUM
ecletica-1329	343	12	,	,	PUNCT
ecletica-1329	343	13	n.	n.	NOUN
ecletica-1329	343	14	1	1	NUM
ecletica-1329	343	15	,	,	PUNCT
ecletica-1329	343	16	2023	2023	NUM
ecletica-1329	343	17	,	,	PUNCT
ecletica-1329	343	18	55	55	NUM
ecletica-1329	343	19	-	-	SYM
ecletica-1329	343	20	71	71	NUM
ecletica-1329	343	21	issn	issn	NOUN
ecletica-1329	343	22	:	:	PUNCT
ecletica-1329	343	23	1678	1678	NUM
ecletica-1329	343	24	-	-	SYM
ecletica-1329	343	25	4618	4618	NUM
ecletica-1329	343	26	doi	doi	NOUN
ecletica-1329	343	27	:	:	PUNCT
ecletica-1329	343	28	10.26850/1678	10.26850/1678	NUM
ecletica-1329	343	29	-	-	PUNCT
ecletica-1329	343	30	4618eqj.v48.1.2023.p55	4618eqj.v48.1.2023.p55	NUM
ecletica-1329	343	31	-	-	PUNCT
ecletica-1329	343	32	71	71	NUM
ecletica-1329	343	33	devesa	devesa	NOUN
ecletica-1329	343	34	,	,	PUNCT
ecletica-1329	343	35	s.	s.	PROPN
ecletica-1329	343	36	s.	s.	PROPN
ecletica-1329	343	37	;	;	PUNCT
ecletica-1329	343	38	bray	bray	PROPN
ecletica-1329	343	39	,	,	PUNCT
ecletica-1329	343	40	f.	f.	PROPN
ecletica-1329	343	41	;	;	PUNCT
ecletica-1329	343	42	vizcaino	vizcaino	ADJ
ecletica-1329	343	43	,	,	PUNCT
ecletica-1329	343	44	a.	a.	NOUN
ecletica-1329	343	45	p.	p.	NOUN
ecletica-1329	343	46	;	;	PUNCT
ecletica-1329	343	47	parkin	parkin	PROPN
ecletica-1329	343	48	,	,	PUNCT
ecletica-1329	343	49	d.	d.	PROPN
ecletica-1329	343	50	m.	m.	PROPN
ecletica-1329	343	51	international	international	PROPN
ecletica-1329	343	52	lung	lung	NOUN
ecletica-1329	343	53	cancer	cancer	NOUN
ecletica-1329	343	54	trends	trend	NOUN
ecletica-1329	343	55	by	by	ADP
ecletica-1329	343	56	histologic	histologic	ADJ
ecletica-1329	343	57	type	type	NOUN
ecletica-1329	343	58	:	:	PUNCT
ecletica-1329	343	59	male	male	ADJ
ecletica-1329	343	60	:	:	PUNCT
ecletica-1329	343	61	female	female	ADJ
ecletica-1329	343	62	differences	difference	NOUN
ecletica-1329	343	63	diminishing	diminishing	NOUN
ecletica-1329	343	64	and	and	CCONJ
ecletica-1329	343	65	adenocarcinoma	adenocarcinoma	NOUN
ecletica-1329	343	66	rates	rate	NOUN
ecletica-1329	343	67	rising	rise	VERB
ecletica-1329	343	68	.	.	PUNCT
ecletica-1329	344	1	int	int	NOUN
ecletica-1329	344	2	.	.	PUNCT
ecletica-1329	345	1	j.	j.	PROPN
ecletica-1329	345	2	cancer	cancer	PROPN
ecletica-1329	345	3	.	.	PUNCT
ecletica-1329	346	1	2005	2005	NUM
ecletica-1329	346	2	,	,	PUNCT
ecletica-1329	346	3	117	117	NUM
ecletica-1329	346	4	(	(	PUNCT
ecletica-1329	346	5	2	2	NUM
ecletica-1329	346	6	)	)	PUNCT
ecletica-1329	346	7	,	,	PUNCT
ecletica-1329	346	8	294–299	294–299	NUM
ecletica-1329	346	9	https://doi.org/10.1002/ijc.21183	https://doi.org/10.1002/ijc.21183	PROPN
ecletica-1329	346	10	dixon	dixon	PROPN
ecletica-1329	346	11	,	,	PUNCT
ecletica-1329	346	12	s.	s.	PROPN
ecletica-1329	346	13	l.	l.	PROPN
ecletica-1329	346	14	;	;	PUNCT
ecletica-1329	346	15	smondyrev	smondyrev	PROPN
ecletica-1329	346	16	,	,	PUNCT
ecletica-1329	346	17	a.	a.	NOUN
ecletica-1329	346	18	m.	m.	NOUN
ecletica-1329	346	19	;	;	PUNCT
ecletica-1329	346	20	knoll	knoll	PROPN
ecletica-1329	346	21	,	,	PUNCT
ecletica-1329	346	22	e.	e.	PROPN
ecletica-1329	346	23	h.	h.	PROPN
ecletica-1329	346	24	;	;	PUNCT
ecletica-1329	346	25	rao	rao	PROPN
ecletica-1329	346	26	,	,	PUNCT
ecletica-1329	346	27	s.	s.	PROPN
ecletica-1329	346	28	n.	n.	PROPN
ecletica-1329	346	29	;	;	PUNCT
ecletica-1329	346	30	shaw	shaw	PROPN
ecletica-1329	346	31	,	,	PUNCT
ecletica-1329	346	32	d.	d.	PROPN
ecletica-1329	346	33	e.	e.	PROPN
ecletica-1329	346	34	;	;	PUNCT
ecletica-1329	346	35	friesner	friesner	PROPN
ecletica-1329	346	36	,	,	PUNCT
ecletica-1329	346	37	r.	r.	PROPN
ecletica-1329	346	38	a.	a.	NOUN
ecletica-1329	346	39	phase	phase	NOUN
ecletica-1329	346	40	:	:	PUNCT
ecletica-1329	346	41	a	a	DET
ecletica-1329	346	42	new	new	ADJ
ecletica-1329	346	43	engine	engine	NOUN
ecletica-1329	346	44	for	for	ADP
ecletica-1329	346	45	pharmacophore	pharmacophore	ADJ
ecletica-1329	346	46	perception	perception	NOUN
ecletica-1329	346	47	,	,	PUNCT
ecletica-1329	346	48	3d	3d	NUM
ecletica-1329	346	49	qsar	qsar	PROPN
ecletica-1329	346	50	model	model	PROPN
ecletica-1329	346	51	development	development	NOUN
ecletica-1329	346	52	,	,	PUNCT
ecletica-1329	346	53	and	and	CCONJ
ecletica-1329	346	54	3d	3d	NUM
ecletica-1329	346	55	database	database	NOUN
ecletica-1329	346	56	screening	screen	VERB
ecletica-1329	346	57	:	:	PUNCT
ecletica-1329	346	58	1	1	X
ecletica-1329	346	59	.	.	X
ecletica-1329	346	60	methodology	methodology	NOUN
ecletica-1329	346	61	and	and	CCONJ
ecletica-1329	346	62	preliminary	preliminary	ADJ
ecletica-1329	346	63	results	result	NOUN
ecletica-1329	346	64	.	.	PUNCT
ecletica-1329	347	1	j.	j.	PROPN
ecletica-1329	347	2	comput	comput	PROPN
ecletica-1329	347	3	.	.	PUNCT
ecletica-1329	347	4	aided	aid	VERB
ecletica-1329	347	5	mol	mol	PROPN
ecletica-1329	347	6	.	.	PUNCT
ecletica-1329	348	1	des	des	PROPN
ecletica-1329	348	2	.	.	PROPN
ecletica-1329	348	3	2006	2006	NUM
ecletica-1329	348	4	,	,	PUNCT
ecletica-1329	348	5	20	20	NUM
ecletica-1329	348	6	(	(	PUNCT
ecletica-1329	348	7	10–11	10–11	NUM
ecletica-1329	348	8	)	)	PUNCT
ecletica-1329	348	9	,	,	PUNCT
ecletica-1329	348	10	647	647	NUM
ecletica-1329	348	11	–	–	PUNCT
ecletica-1329	348	12	671	671	NUM
ecletica-1329	348	13	.	.	PUNCT
ecletica-1329	349	1	https://doi.org/10.1007/s10822-006-9087-6	https://doi.org/10.1007/s10822-006-9087-6	NUM
ecletica-1329	349	2	faidallah	faidallah	PROPN
ecletica-1329	349	3	,	,	PUNCT
ecletica-1329	349	4	h.	h.	PROPN
ecletica-1329	349	5	m.	m.	NOUN
ecletica-1329	349	6	;	;	PUNCT
ecletica-1329	349	7	rostom	rostom	PROPN
ecletica-1329	349	8	,	,	PUNCT
ecletica-1329	349	9	s.	s.	PROPN
ecletica-1329	349	10	a.	a.	PROPN
ecletica-1329	349	11	f.	f.	PROPN
ecletica-1329	349	12	synthesis	synthesis	PROPN
ecletica-1329	349	13	,	,	PUNCT
ecletica-1329	349	14	in	in	ADP
ecletica-1329	349	15	vitro	vitro	X
ecletica-1329	349	16	antitumor	antitumor	PROPN
ecletica-1329	349	17	evaluation	evaluation	NOUN
ecletica-1329	349	18	and	and	CCONJ
ecletica-1329	349	19	dna	dna	NOUN
ecletica-1329	349	20	binding	bind	VERB
ecletica-1329	349	21	study	study	NOUN
ecletica-1329	349	22	of	of	ADP
ecletica-1329	349	23	novel	novel	ADJ
ecletica-1329	349	24	tetrahydroquinolines	tetrahydroquinoline	NOUN
ecletica-1329	349	25	and	and	CCONJ
ecletica-1329	349	26	some	some	DET
ecletica-1329	349	27	derived	derived	ADJ
ecletica-1329	349	28	tricyclic	tricyclic	ADJ
ecletica-1329	349	29	and	and	CCONJ
ecletica-1329	349	30	tetracyclic	tetracyclic	NOUN
ecletica-1329	349	31	ring	ring	NOUN
ecletica-1329	349	32	systems	system	NOUN
ecletica-1329	349	33	.	.	PUNCT
ecletica-1329	350	1	eur	eur	PROPN
ecletica-1329	350	2	.	.	PUNCT
ecletica-1329	351	1	j.	j.	PROPN
ecletica-1329	351	2	med	med	PROPN
ecletica-1329	351	3	.	.	PROPN
ecletica-1329	351	4	chem	chem	PROPN
ecletica-1329	351	5	.	.	PUNCT
ecletica-1329	352	1	2013	2013	NUM
ecletica-1329	352	2	,	,	PUNCT
ecletica-1329	352	3	63	63	NUM
ecletica-1329	352	4	,	,	PUNCT
ecletica-1329	352	5	133	133	NUM
ecletica-1329	352	6	–	–	PUNCT
ecletica-1329	352	7	143	143	NUM
ecletica-1329	352	8	.	.	PUNCT
ecletica-1329	353	1	https://doi.org/10.1016/j.ejmech.2013.02.006	https://doi.org/10.1016/j.ejmech.2013.02.006	ADJ
ecletica-1329	353	2	fathy	fathy	NOUN
ecletica-1329	353	3	,	,	PUNCT
ecletica-1329	353	4	u.	u.	PROPN
ecletica-1329	353	5	;	;	PUNCT
ecletica-1329	353	6	azzam	azzam	PROPN
ecletica-1329	353	7	,	,	PUNCT
ecletica-1329	353	8	m.	m.	NOUN
ecletica-1329	353	9	a.	a.	PROPN
ecletica-1329	353	10	;	;	PUNCT
ecletica-1329	353	11	mahdy	mahdy	NOUN
ecletica-1329	353	12	,	,	PUNCT
ecletica-1329	353	13	f.	f.	PROPN
ecletica-1329	353	14	;	;	PUNCT
ecletica-1329	353	15	el	el	PROPN
ecletica-1329	353	16	-	-	PUNCT
ecletica-1329	353	17	maghraby	maghraby	PROPN
ecletica-1329	353	18	,	,	PUNCT
ecletica-1329	353	19	s.	s.	PROPN
ecletica-1329	353	20	;	;	PUNCT
ecletica-1329	353	21	allam	allam	PROPN
ecletica-1329	353	22	,	,	PUNCT
ecletica-1329	353	23	r.	r.	PROPN
ecletica-1329	353	24	m.	m.	NOUN
ecletica-1329	353	25	synthesis	synthesis	NOUN
ecletica-1329	353	26	and	and	CCONJ
ecletica-1329	353	27	in	in	ADP
ecletica-1329	353	28	vitro	vitro	X
ecletica-1329	353	29	anticancer	anticancer	NOUN
ecletica-1329	353	30	activity	activity	NOUN
ecletica-1329	353	31	of	of	ADP
ecletica-1329	353	32	some	some	DET
ecletica-1329	353	33	novel	novel	NOUN
ecletica-1329	353	34	tetrahydroquinoline	tetrahydroquinoline	ADJ
ecletica-1329	353	35	derivatives	derivative	NOUN
ecletica-1329	353	36	bearing	bear	VERB
ecletica-1329	353	37	pyrazol	pyrazol	NOUN
ecletica-1329	353	38	and	and	CCONJ
ecletica-1329	353	39	hydrazide	hydrazide	ADJ
ecletica-1329	353	40	moiety	moiety	PROPN
ecletica-1329	353	41	.	.	PUNCT
ecletica-1329	354	1	j.	j.	PROPN
ecletica-1329	354	2	heterocycl	heterocycl	PROPN
ecletica-1329	354	3	.	.	PUNCT
ecletica-1329	354	4	chem	chem	PROPN
ecletica-1329	354	5	.	.	PUNCT
ecletica-1329	355	1	2020	2020	NUM
ecletica-1329	355	2	,	,	PUNCT
ecletica-1329	355	3	57	57	NUM
ecletica-1329	355	4	(	(	PUNCT
ecletica-1329	355	5	5	5	NUM
ecletica-1329	355	6	)	)	PUNCT
ecletica-1329	355	7	,	,	PUNCT
ecletica-1329	355	8	2108	2108	NUM
ecletica-1329	355	9	–	–	PUNCT
ecletica-1329	355	10	2120	2120	NUM
ecletica-1329	355	11	.	.	PUNCT
ecletica-1329	356	1	https://doi.org/10.1002/jhet.3930	https://doi.org/10.1002/jhet.3930	PROPN
ecletica-1329	356	2	grisoni	grisoni	PROPN
ecletica-1329	356	3	,	,	PUNCT
ecletica-1329	356	4	f.	f.	PROPN
ecletica-1329	356	5	;	;	PUNCT
ecletica-1329	356	6	ballabio	ballabio	VERB
ecletica-1329	356	7	,	,	PUNCT
ecletica-1329	356	8	d.	d.	PROPN
ecletica-1329	356	9	;	;	PUNCT
ecletica-1329	356	10	todeschini	todeschini	PROPN
ecletica-1329	356	11	,	,	PUNCT
ecletica-1329	356	12	r.	r.	PROPN
ecletica-1329	356	13	;	;	PUNCT
ecletica-1329	356	14	consonni	consonni	PROPN
ecletica-1329	356	15	,	,	PUNCT
ecletica-1329	356	16	v.	v.	ADP
ecletica-1329	356	17	molecular	molecular	ADJ
ecletica-1329	356	18	descriptors	descriptor	NOUN
ecletica-1329	356	19	for	for	ADP
ecletica-1329	356	20	structure	structure	NOUN
ecletica-1329	356	21	–	–	PUNCT
ecletica-1329	356	22	activity	activity	NOUN
ecletica-1329	356	23	applications	application	NOUN
ecletica-1329	356	24	:	:	PUNCT
ecletica-1329	356	25	a	a	DET
ecletica-1329	356	26	hands	hand	NOUN
ecletica-1329	356	27	-	-	PUNCT
ecletica-1329	356	28	on	on	ADP
ecletica-1329	356	29	approach	approach	NOUN
ecletica-1329	356	30	.	.	PUNCT
ecletica-1329	357	1	in	in	ADP
ecletica-1329	357	2	computational	computational	ADJ
ecletica-1329	357	3	toxicology	toxicology	NOUN
ecletica-1329	357	4	.	.	PUNCT
ecletica-1329	358	1	nicolotti	nicolotti	VERB
ecletica-1329	358	2	,	,	PUNCT
ecletica-1329	358	3	o.	o.	NOUN
ecletica-1329	358	4	ed	ed	NOUN
ecletica-1329	358	5	.	.	PUNCT
ecletica-1329	358	6	;	;	PUNCT
ecletica-1329	358	7	humana	humana	PROPN
ecletica-1329	358	8	press	press	PROPN
ecletica-1329	358	9	,	,	PUNCT
ecletica-1329	358	10	2018	2018	NUM
ecletica-1329	358	11	;	;	PUNCT
ecletica-1329	359	1	vol	vol	NOUN
ecletica-1329	359	2	.	.	NOUN
ecletica-1329	359	3	1800	1800	NUM
ecletica-1329	359	4	,	,	PUNCT
ecletica-1329	359	5	3–53	3–53	NOUN
ecletica-1329	359	6	.	.	PUNCT
ecletica-1329	360	1	https://doi.org/10.1007/978-1-4939-7899-1_1	https://doi.org/10.1007/978-1-4939-7899-1_1	PROPN
ecletica-1329	360	2	hayat	hayat	PROPN
ecletica-1329	360	3	,	,	PUNCT
ecletica-1329	360	4	f.	f.	PROPN
ecletica-1329	360	5	;	;	PUNCT
ecletica-1329	360	6	salahuddin	salahuddin	PROPN
ecletica-1329	360	7	,	,	PUNCT
ecletica-1329	360	8	a.	a.	NOUN
ecletica-1329	360	9	;	;	PUNCT
ecletica-1329	360	10	umar	umar	PROPN
ecletica-1329	360	11	,	,	PUNCT
ecletica-1329	360	12	s.	s.	PROPN
ecletica-1329	360	13	;	;	PUNCT
ecletica-1329	360	14	azam	azam	PROPN
ecletica-1329	360	15	,	,	PUNCT
ecletica-1329	360	16	a.	a.	NOUN
ecletica-1329	360	17	synthesis	synthesis	NOUN
ecletica-1329	360	18	,	,	PUNCT
ecletica-1329	360	19	characterization	characterization	NOUN
ecletica-1329	360	20	,	,	PUNCT
ecletica-1329	360	21	antiamoebic	antiamoebic	ADJ
ecletica-1329	360	22	activity	activity	NOUN
ecletica-1329	360	23	and	and	CCONJ
ecletica-1329	360	24	cytotoxicity	cytotoxicity	NOUN
ecletica-1329	360	25	of	of	ADP
ecletica-1329	360	26	novel	novel	ADJ
ecletica-1329	360	27	series	series	NOUN
ecletica-1329	360	28	of	of	ADP
ecletica-1329	360	29	pyrazoline	pyrazoline	NOUN
ecletica-1329	360	30	derivatives	derivative	NOUN
ecletica-1329	360	31	bearing	bear	VERB
ecletica-1329	360	32	quinoline	quinoline	NOUN
ecletica-1329	360	33	tail	tail	NOUN
ecletica-1329	360	34	.	.	PUNCT
ecletica-1329	361	1	eur	eur	PROPN
ecletica-1329	361	2	.	.	PUNCT
ecletica-1329	362	1	j.	j.	PROPN
ecletica-1329	362	2	med	med	PROPN
ecletica-1329	362	3	.	.	PROPN
ecletica-1329	362	4	chem	chem	PROPN
ecletica-1329	362	5	.	.	PUNCT
ecletica-1329	363	1	2010	2010	NUM
ecletica-1329	363	2	,	,	PUNCT
ecletica-1329	363	3	45	45	NUM
ecletica-1329	363	4	(	(	PUNCT
ecletica-1329	363	5	10	10	NUM
ecletica-1329	363	6	)	)	PUNCT
ecletica-1329	363	7	,	,	PUNCT
ecletica-1329	364	1	4669–4675	4669–4675	NUM
ecletica-1329	364	2	.	.	PUNCT
ecletica-1329	365	1	https://doi.org/10.1016/j.ejmech.2010.07.028	https://doi.org/10.1016/j.ejmech.2010.07.028	PROPN
ecletica-1329	365	2	hollenberg	hollenberg	PROPN
ecletica-1329	365	3	,	,	PUNCT
ecletica-1329	365	4	p.	p.	PROPN
ecletica-1329	365	5	f.	f.	PROPN
ecletica-1329	365	6	characteristics	characteristics	PROPN
ecletica-1329	365	7	and	and	CCONJ
ecletica-1329	365	8	common	common	ADJ
ecletica-1329	365	9	properties	property	NOUN
ecletica-1329	365	10	of	of	ADP
ecletica-1329	365	11	inhibitors	inhibitor	NOUN
ecletica-1329	365	12	,	,	PUNCT
ecletica-1329	365	13	inducers	inducer	NOUN
ecletica-1329	365	14	,	,	PUNCT
ecletica-1329	365	15	and	and	CCONJ
ecletica-1329	365	16	activators	activator	NOUN
ecletica-1329	365	17	of	of	ADP
ecletica-1329	365	18	cyp	cyp	ADJ
ecletica-1329	365	19	enzymes	enzyme	NOUN
ecletica-1329	365	20	.	.	PUNCT
ecletica-1329	366	1	drug	drug	NOUN
ecletica-1329	366	2	metab	metab	PROPN
ecletica-1329	366	3	.	.	PUNCT
ecletica-1329	367	1	rev	rev	PROPN
ecletica-1329	367	2	.	.	PROPN
ecletica-1329	367	3	2002	2002	NUM
ecletica-1329	367	4	,	,	PUNCT
ecletica-1329	367	5	34	34	NUM
ecletica-1329	367	6	(	(	PUNCT
ecletica-1329	367	7	1–2	1–2	NUM
ecletica-1329	367	8	)	)	PUNCT
ecletica-1329	367	9	,	,	PUNCT
ecletica-1329	367	10	17–35	17–35	NUM
ecletica-1329	367	11	.	.	PUNCT
ecletica-1329	368	1	https://doi.org/10.1081/dmr-120001387	https://doi.org/10.1081/dmr-120001387	PROPN
ecletica-1329	368	2	ibrahim	ibrahim	PROPN
ecletica-1329	368	3	,	,	PUNCT
ecletica-1329	368	4	m.	m.	NOUN
ecletica-1329	368	5	t.	t.	PROPN
ecletica-1329	368	6	;	;	PUNCT
ecletica-1329	368	7	uzairu	uzairu	NOUN
ecletica-1329	368	8	,	,	PUNCT
ecletica-1329	368	9	a.	a.	NOUN
ecletica-1329	368	10	;	;	PUNCT
ecletica-1329	368	11	uba	uba	PROPN
ecletica-1329	368	12	,	,	PUNCT
ecletica-1329	368	13	s.	s.	PROPN
ecletica-1329	368	14	;	;	PUNCT
ecletica-1329	368	15	shallangwa	shallangwa	PROPN
ecletica-1329	368	16	,	,	PUNCT
ecletica-1329	368	17	g.	g.	PROPN
ecletica-1329	368	18	a.	a.	PROPN
ecletica-1329	368	19	quantitative	quantitative	ADJ
ecletica-1329	368	20	structure	structure	NOUN
ecletica-1329	368	21	-	-	PUNCT
ecletica-1329	368	22	activity	activity	NOUN
ecletica-1329	368	23	relationship	relationship	NOUN
ecletica-1329	368	24	,	,	PUNCT
ecletica-1329	368	25	molecular	molecular	ADJ
ecletica-1329	368	26	docking	docking	NOUN
ecletica-1329	368	27	,	,	PUNCT
ecletica-1329	368	28	drug	drug	NOUN
ecletica-1329	368	29	-	-	PUNCT
ecletica-1329	368	30	likeness	likeness	NOUN
ecletica-1329	368	31	,	,	PUNCT
ecletica-1329	368	32	and	and	CCONJ
ecletica-1329	368	33	pharmacokinetic	pharmacokinetic	ADJ
ecletica-1329	368	34	studies	study	NOUN
ecletica-1329	368	35	of	of	ADP
ecletica-1329	368	36	some	some	DET
ecletica-1329	368	37	non	non	ADJ
ecletica-1329	368	38	-	-	ADJ
ecletica-1329	368	39	small	small	ADJ
ecletica-1329	368	40	cell	cell	NOUN
ecletica-1329	368	41	lung	lung	NOUN
ecletica-1329	368	42	cancer	cancer	NOUN
ecletica-1329	368	43	therapeutic	therapeutic	ADJ
ecletica-1329	368	44	agents	agent	NOUN
ecletica-1329	368	45	.	.	PUNCT
ecletica-1329	369	1	beni	beni	ADJ
ecletica-1329	369	2	-	-	ADJ
ecletica-1329	369	3	suef	suef	ADJ
ecletica-1329	369	4	univ	univ	PROPN
ecletica-1329	369	5	.	.	PUNCT
ecletica-1329	370	1	j.	j.	PROPN
ecletica-1329	370	2	basic	basic	ADJ
ecletica-1329	370	3	appl	appl	PROPN
ecletica-1329	370	4	.	.	PUNCT
ecletica-1329	371	1	sci	sci	PROPN
ecletica-1329	371	2	.	.	PROPN
ecletica-1329	371	3	2020	2020	NUM
ecletica-1329	371	4	,	,	PUNCT
ecletica-1329	371	5	9	9	NUM
ecletica-1329	371	6	,	,	PUNCT
ecletica-1329	371	7	49	49	NUM
ecletica-1329	371	8	.	.	PUNCT
ecletica-1329	372	1	https://doi.org/10.1186/s43088-020-00077-5	https://doi.org/10.1186/s43088-020-00077-5	PROPN
ecletica-1329	372	2	johnson	johnson	PROPN
ecletica-1329	372	3	,	,	PUNCT
ecletica-1329	372	4	t.	t.	PROPN
ecletica-1329	372	5	o.	o.	PROPN
ecletica-1329	372	6	;	;	PUNCT
ecletica-1329	372	7	adegboyega	adegboyega	PROPN
ecletica-1329	372	8	,	,	PUNCT
ecletica-1329	372	9	a.	a.	PROPN
ecletica-1329	372	10	e.	e.	PROPN
ecletica-1329	372	11	;	;	PUNCT
ecletica-1329	372	12	iwaloye	iwaloye	NOUN
ecletica-1329	372	13	,	,	PUNCT
ecletica-1329	372	14	o.	o.	PROPN
ecletica-1329	372	15	;	;	PUNCT
ecletica-1329	372	16	eseola	eseola	PROPN
ecletica-1329	372	17	,	,	PUNCT
ecletica-1329	372	18	o.	o.	PROPN
ecletica-1329	372	19	a.	a.	NOUN
ecletica-1329	372	20	;	;	PUNCT
ecletica-1329	372	21	plass	plass	PROPN
ecletica-1329	372	22	,	,	PUNCT
ecletica-1329	372	23	w.	w.	NOUN
ecletica-1329	372	24	;	;	PUNCT
ecletica-1329	372	25	afolabi	afolabi	NOUN
ecletica-1329	372	26	,	,	PUNCT
ecletica-1329	372	27	b.	b.	PROPN
ecletica-1329	372	28	;	;	PUNCT
ecletica-1329	372	29	rotimi	rotimi	PROPN
ecletica-1329	372	30	,	,	PUNCT
ecletica-1329	372	31	d.	d.	PROPN
ecletica-1329	372	32	;	;	PUNCT
ecletica-1329	372	33	ahmed	ahmed	PROPN
ecletica-1329	372	34	,	,	PUNCT
ecletica-1329	372	35	e.	e.	PROPN
ecletica-1329	372	36	;	;	PUNCT
ecletica-1329	372	37	albrakati	albrakati	PROPN
ecletica-1329	372	38	,	,	PUNCT
ecletica-1329	372	39	a.	a.	NOUN
ecletica-1329	372	40	;	;	PUNCT
ecletica-1329	372	41	batiha	batiha	VERB
ecletica-1329	372	42	,	,	PUNCT
ecletica-1329	372	43	g.	g.	PROPN
ecletica-1329	372	44	e.	e.	PROPN
ecletica-1329	372	45	;	;	PUNCT
ecletica-1329	372	46	adeyemi	adeyemi	ADV
ecletica-1329	372	47	,	,	PUNCT
ecletica-1329	372	48	o.	o.	PROPN
ecletica-1329	372	49	s.	s.	PROPN
ecletica-1329	372	50	computational	computational	ADJ
ecletica-1329	372	51	study	study	NOUN
ecletica-1329	372	52	of	of	ADP
ecletica-1329	372	53	the	the	DET
ecletica-1329	372	54	therapeutic	therapeutic	ADJ
ecletica-1329	372	55	potentials	potential	NOUN
ecletica-1329	372	56	of	of	ADP
ecletica-1329	372	57	a	a	DET
ecletica-1329	372	58	new	new	ADJ
ecletica-1329	372	59	series	series	NOUN
ecletica-1329	372	60	of	of	ADP
ecletica-1329	372	61	imidazole	imidazole	NOUN
ecletica-1329	372	62	derivatives	derivative	NOUN
ecletica-1329	372	63	against	against	ADP
ecletica-1329	372	64	sars	sar	NOUN
ecletica-1329	372	65	-	-	PUNCT
ecletica-1329	372	66	cov-2	cov-2	NOUN
ecletica-1329	372	67	.	.	PUNCT
ecletica-1329	373	1	j.	j.	PROPN
ecletica-1329	373	2	pharmacol	pharmacol	PROPN
ecletica-1329	373	3	.	.	PUNCT
ecletica-1329	374	1	sci	sci	PROPN
ecletica-1329	374	2	.	.	PROPN
ecletica-1329	374	3	2021	2021	NUM
ecletica-1329	374	4	,	,	PUNCT
ecletica-1329	374	5	147	147	NUM
ecletica-1329	374	6	(	(	PUNCT
ecletica-1329	374	7	1	1	NUM
ecletica-1329	374	8	)	)	PUNCT
ecletica-1329	374	9	,	,	PUNCT
ecletica-1329	374	10	62	62	NUM
ecletica-1329	374	11	–	–	SYM
ecletica-1329	374	12	71	71	NUM
ecletica-1329	374	13	.	.	PUNCT
ecletica-1329	375	1	https://doi.org/10.1016/j.jphs.2021.05.004	https://doi.org/10.1016/j.jphs.2021.05.004	NOUN
ecletica-1329	375	2	lapa	lapa	X
ecletica-1329	375	3	,	,	PUNCT
ecletica-1329	375	4	g.	g.	PROPN
ecletica-1329	375	5	b.	b.	PROPN
ecletica-1329	375	6	;	;	PUNCT
ecletica-1329	375	7	bekker	bekker	PROPN
ecletica-1329	375	8	,	,	PUNCT
ecletica-1329	375	9	o.	o.	PROPN
ecletica-1329	375	10	b.	b.	PROPN
ecletica-1329	375	11	;	;	PUNCT
ecletica-1329	375	12	mirchink	mirchink	PROPN
ecletica-1329	375	13	,	,	PUNCT
ecletica-1329	375	14	e.	e.	PROPN
ecletica-1329	375	15	p.	p.	PROPN
ecletica-1329	375	16	;	;	PUNCT
ecletica-1329	375	17	danilenko	danilenko	PROPN
ecletica-1329	375	18	,	,	PUNCT
ecletica-1329	375	19	v.	v.	ADP
ecletica-1329	375	20	n.	n.	NOUN
ecletica-1329	375	21	;	;	PUNCT
ecletica-1329	375	22	preobrazhenskaya	preobrazhenskaya	NOUN
ecletica-1329	375	23	,	,	PUNCT
ecletica-1329	375	24	m.	m.	NOUN
ecletica-1329	375	25	n.	n.	PROPN
ecletica-1329	375	26	regioselective	regioselective	PROPN
ecletica-1329	375	27	acylation	acylation	NOUN
ecletica-1329	375	28	of	of	ADP
ecletica-1329	375	29	congeners	congener	NOUN
ecletica-1329	375	30	of	of	ADP
ecletica-1329	375	31	3	3	NUM
ecletica-1329	375	32	-	-	PUNCT
ecletica-1329	375	33	amino-1h	amino-1h	NOUN
ecletica-1329	375	34	-	-	PUNCT
ecletica-1329	375	35	pyrazolo[3,4	pyrazolo[3,4	NOUN
ecletica-1329	375	36	-	-	PUNCT
ecletica-1329	375	37	b]quinolines	b]quinoline	NOUN
ecletica-1329	375	38	,	,	PUNCT
ecletica-1329	375	39	their	their	PRON
ecletica-1329	375	40	activity	activity	NOUN
ecletica-1329	375	41	on	on	ADP
ecletica-1329	375	42	bacterial	bacterial	ADJ
ecletica-1329	375	43	serine	serine	NOUN
ecletica-1329	375	44	/	/	SYM
ecletica-1329	375	45	threonine	threonine	ADJ
ecletica-1329	375	46	protein	protein	NOUN
ecletica-1329	375	47	kinases	kinase	NOUN
ecletica-1329	375	48	and	and	CCONJ
ecletica-1329	375	49	in	in	ADP
ecletica-1329	375	50	vitro	vitro	X
ecletica-1329	375	51	antibacterial	antibacterial	ADJ
ecletica-1329	375	52	(	(	PUNCT
ecletica-1329	375	53	including	include	VERB
ecletica-1329	375	54	antimycobacterial	antimycobacterial	ADJ
ecletica-1329	375	55	)	)	PUNCT
ecletica-1329	375	56	activity	activity	NOUN
ecletica-1329	375	57	.	.	PUNCT
ecletica-1329	376	1	j.	j.	PROPN
ecletica-1329	376	2	enzyme	enzyme	NOUN
ecletica-1329	376	3	inhib	inhib	NOUN
ecletica-1329	376	4	.	.	PUNCT
ecletica-1329	377	1	med	med	PROPN
ecletica-1329	377	2	.	.	PROPN
ecletica-1329	377	3	chem	chem	PROPN
ecletica-1329	377	4	.	.	PUNCT
ecletica-1329	378	1	2013	2013	NUM
ecletica-1329	378	2	,	,	PUNCT
ecletica-1329	378	3	28	28	NUM
ecletica-1329	378	4	(	(	PUNCT
ecletica-1329	378	5	5	5	NUM
ecletica-1329	378	6	)	)	PUNCT
ecletica-1329	378	7	,	,	PUNCT
ecletica-1329	378	8	1088–1093	1088–1093	NUM
ecletica-1329	378	9	.	.	PUNCT
ecletica-1329	379	1	https://doi.org/10.3109/14756366.2012.716056	https://doi.org/10.3109/14756366.2012.716056	PROPN
ecletica-1329	379	2	lipinski	lipinski	PROPN
ecletica-1329	379	3	,	,	PUNCT
ecletica-1329	379	4	c.	c.	PROPN
ecletica-1329	379	5	a.	a.	PROPN
ecletica-1329	379	6	;	;	PUNCT
ecletica-1329	379	7	lombardo	lombardo	PROPN
ecletica-1329	379	8	,	,	PUNCT
ecletica-1329	379	9	f.	f.	PROPN
ecletica-1329	379	10	;	;	PUNCT
ecletica-1329	379	11	dominy	dominy	PROPN
ecletica-1329	379	12	,	,	PUNCT
ecletica-1329	379	13	b.	b.	PROPN
ecletica-1329	379	14	w.	w.	PROPN
ecletica-1329	379	15	;	;	PUNCT
ecletica-1329	379	16	feeney	feeney	PROPN
ecletica-1329	379	17	,	,	PUNCT
ecletica-1329	379	18	p.	p.	PROPN
ecletica-1329	379	19	j.	j.	PROPN
ecletica-1329	379	20	experimental	experimental	PROPN
ecletica-1329	379	21	and	and	CCONJ
ecletica-1329	379	22	computational	computational	ADJ
ecletica-1329	379	23	approaches	approach	NOUN
ecletica-1329	379	24	to	to	PART
ecletica-1329	379	25	estimate	estimate	VERB
ecletica-1329	379	26	solubility	solubility	NOUN
ecletica-1329	379	27	and	and	CCONJ
ecletica-1329	379	28	permeability	permeability	NOUN
ecletica-1329	379	29	in	in	ADP
ecletica-1329	379	30	drug	drug	NOUN
ecletica-1329	379	31	discovery	discovery	NOUN
ecletica-1329	379	32	and	and	CCONJ
ecletica-1329	379	33	development	development	NOUN
ecletica-1329	379	34	settings	setting	NOUN
ecletica-1329	379	35	.	.	PUNCT
ecletica-1329	380	1	adv	adv	PROPN
ecletica-1329	380	2	.	.	PUNCT
ecletica-1329	380	3	drug	drug	PROPN
ecletica-1329	380	4	deliv	deliv	PROPN
ecletica-1329	380	5	.	.	PUNCT
ecletica-1329	381	1	rev	rev	PROPN
ecletica-1329	381	2	.	.	PROPN
ecletica-1329	381	3	2001	2001	NUM
ecletica-1329	381	4	,	,	PUNCT
ecletica-1329	381	5	46	46	NUM
ecletica-1329	381	6	(	(	PUNCT
ecletica-1329	381	7	1–3	1–3	NOUN
ecletica-1329	381	8	)	)	PUNCT
ecletica-1329	381	9	,	,	PUNCT
ecletica-1329	381	10	3–26	3–26	NUM
ecletica-1329	381	11	.	.	PUNCT
ecletica-1329	382	1	https://doi.org/10.1016/s0169-409x(00)00129-0	https://doi.org/10.1016/s0169-409x(00)00129-0	PROPN
ecletica-1329	382	2	loving	loving	NOUN
ecletica-1329	382	3	,	,	PUNCT
ecletica-1329	382	4	k.	k.	PROPN
ecletica-1329	382	5	;	;	PUNCT
ecletica-1329	382	6	salam	salam	PROPN
ecletica-1329	382	7	,	,	PUNCT
ecletica-1329	382	8	n.	n.	PROPN
ecletica-1329	382	9	k.	k.	PROPN
ecletica-1329	382	10	;	;	PUNCT
ecletica-1329	382	11	sherman	sherman	PROPN
ecletica-1329	382	12	,	,	PUNCT
ecletica-1329	382	13	w.	w.	PROPN
ecletica-1329	382	14	energetic	energetic	ADJ
ecletica-1329	382	15	analysis	analysis	NOUN
ecletica-1329	382	16	of	of	ADP
ecletica-1329	382	17	fragment	fragment	ADJ
ecletica-1329	382	18	docking	docking	NOUN
ecletica-1329	382	19	and	and	CCONJ
ecletica-1329	382	20	application	application	NOUN
ecletica-1329	382	21	to	to	ADP
ecletica-1329	382	22	structure	structure	NOUN
ecletica-1329	382	23	-	-	PUNCT
ecletica-1329	382	24	based	base	VERB
ecletica-1329	382	25	pharmacophore	pharmacophore	ADJ
ecletica-1329	382	26	hypothesis	hypothesis	NOUN
ecletica-1329	382	27	generation	generation	NOUN
ecletica-1329	382	28	.	.	PUNCT
ecletica-1329	383	1	j.	j.	PROPN
ecletica-1329	383	2	comput	comput	PROPN
ecletica-1329	383	3	.	.	PUNCT
ecletica-1329	383	4	aided	aid	VERB
ecletica-1329	383	5	mol	mol	PROPN
ecletica-1329	383	6	.	.	PUNCT
ecletica-1329	384	1	des	des	PROPN
ecletica-1329	384	2	.	.	PROPN
ecletica-1329	384	3	2009	2009	NUM
ecletica-1329	384	4	,	,	PUNCT
ecletica-1329	384	5	23	23	NUM
ecletica-1329	384	6	(	(	PUNCT
ecletica-1329	384	7	8)	8)	NUM
ecletica-1329	384	8	,	,	PUNCT
ecletica-1329	384	9	541–554	541–554	NUM
ecletica-1329	384	10	.	.	PUNCT
ecletica-1329	385	1	https://doi.org/10.1007/s10822009-9268-1	https://doi.org/10.1007/s10822009-9268-1	PROPN
ecletica-1329	385	2	lynch	lynch	PROPN
ecletica-1329	385	3	,	,	PUNCT
ecletica-1329	385	4	t.	t.	PROPN
ecletica-1329	385	5	;	;	PUNCT
ecletica-1329	385	6	price	price	NOUN
ecletica-1329	385	7	,	,	PUNCT
ecletica-1329	385	8	a.	a.	NOUN
ecletica-1329	385	9	the	the	DET
ecletica-1329	385	10	effect	effect	NOUN
ecletica-1329	385	11	of	of	ADP
ecletica-1329	385	12	cytochrome	cytochrome	ADJ
ecletica-1329	385	13	p450	p450	PROPN
ecletica-1329	385	14	metabolism	metabolism	NOUN
ecletica-1329	385	15	on	on	ADP
ecletica-1329	385	16	drug	drug	NOUN
ecletica-1329	385	17	response	response	NOUN
ecletica-1329	385	18	,	,	PUNCT
ecletica-1329	385	19	interactions	interaction	NOUN
ecletica-1329	385	20	,	,	PUNCT
ecletica-1329	385	21	and	and	CCONJ
ecletica-1329	385	22	adverse	adverse	ADJ
ecletica-1329	385	23	effects	effect	NOUN
ecletica-1329	385	24	.	.	PUNCT
ecletica-1329	386	1	am	be	AUX
ecletica-1329	386	2	.	.	PUNCT
ecletica-1329	387	1	fam	fam	PROPN
ecletica-1329	387	2	.	.	PUNCT
ecletica-1329	387	3	physician	physician	PROPN
ecletica-1329	387	4	.	.	PUNCT
ecletica-1329	388	1	2007	2007	NUM
ecletica-1329	388	2	,	,	PUNCT
ecletica-1329	388	3	76	76	NUM
ecletica-1329	388	4	(	(	PUNCT
ecletica-1329	388	5	3	3	NUM
ecletica-1329	388	6	)	)	PUNCT
ecletica-1329	388	7	,	,	PUNCT
ecletica-1329	388	8	391–396	391–396	NUM
ecletica-1329	388	9	.	.	PUNCT
ecletica-1329	389	1	mandewale	mandewale	PROPN
ecletica-1329	389	2	,	,	PUNCT
ecletica-1329	389	3	c.	c.	NOUN
ecletica-1329	389	4	m.	m.	NOUN
ecletica-1329	389	5	;	;	PUNCT
ecletica-1329	389	6	patil	patil	PROPN
ecletica-1329	389	7	,	,	PUNCT
ecletica-1329	389	8	u.	u.	PROPN
ecletica-1329	389	9	c.	c.	PROPN
ecletica-1329	389	10	;	;	PUNCT
ecletica-1329	389	11	shedge	shedge	PROPN
ecletica-1329	389	12	,	,	PUNCT
ecletica-1329	389	13	s.	s.	PROPN
ecletica-1329	389	14	v.	v.	PROPN
ecletica-1329	389	15	;	;	PUNCT
ecletica-1329	389	16	dappadwad	dappadwad	NOUN
ecletica-1329	389	17	,	,	PUNCT
ecletica-1329	389	18	u.	u.	PROPN
ecletica-1329	389	19	r.	r.	PROPN
ecletica-1329	389	20	;	;	PUNCT
ecletica-1329	389	21	yamgar	yamgar	NOUN
ecletica-1329	389	22	,	,	PUNCT
ecletica-1329	389	23	r.	r.	PROPN
ecletica-1329	389	24	s.	s.	PROPN
ecletica-1329	389	25	a	a	DET
ecletica-1329	389	26	review	review	NOUN
ecletica-1329	389	27	on	on	ADP
ecletica-1329	389	28	quinoline	quinoline	ADJ
ecletica-1329	389	29	hydrazone	hydrazone	NOUN
ecletica-1329	389	30	derivatives	derivative	NOUN
ecletica-1329	389	31	as	as	ADP
ecletica-1329	389	32	a	a	DET
ecletica-1329	389	33	new	new	ADJ
ecletica-1329	389	34	class	class	NOUN
ecletica-1329	389	35	of	of	ADP
ecletica-1329	389	36	potent	potent	ADJ
ecletica-1329	389	37	antitubercular	antitubercular	ADJ
ecletica-1329	389	38	and	and	CCONJ
ecletica-1329	389	39	anticancer	anticancer	NOUN
ecletica-1329	389	40	agents	agent	NOUN
ecletica-1329	389	41	.	.	PUNCT
ecletica-1329	390	1	beni	beni	ADJ
ecletica-1329	390	2	-	-	ADJ
ecletica-1329	390	3	suef	suef	ADJ
ecletica-1329	390	4	univ	univ	PROPN
ecletica-1329	390	5	.	.	PUNCT
ecletica-1329	391	1	j.	j.	PROPN
ecletica-1329	391	2	basic	basic	ADJ
ecletica-1329	391	3	appl	appl	PROPN
ecletica-1329	391	4	.	.	PUNCT
ecletica-1329	392	1	sci	sci	PROPN
ecletica-1329	392	2	.	.	PROPN
ecletica-1329	392	3	2017	2017	NUM
ecletica-1329	392	4	,	,	PUNCT
ecletica-1329	392	5	6	6	NUM
ecletica-1329	392	6	(	(	PUNCT
ecletica-1329	392	7	4	4	NUM
ecletica-1329	392	8	)	)	PUNCT
ecletica-1329	392	9	,	,	PUNCT
ecletica-1329	392	10	354–361	354–361	PROPN
ecletica-1329	392	11	.	.	PUNCT
ecletica-1329	393	1	https://doi.org/10.1016/j.bjbas.2017.07.005	https://doi.org/10.1016/j.bjbas.2017.07.005	PROPN
ecletica-1329	393	2	mekheimer	mekheimer	PROPN
ecletica-1329	393	3	,	,	PUNCT
ecletica-1329	393	4	r.	r.	PROPN
ecletica-1329	393	5	a.	a.	PROPN
ecletica-1329	393	6	;	;	PUNCT
ecletica-1329	393	7	al	al	PROPN
ecletica-1329	393	8	-	-	PUNCT
ecletica-1329	393	9	sheikh	sheikh	PROPN
ecletica-1329	393	10	,	,	PUNCT
ecletica-1329	393	11	m.	m.	NOUN
ecletica-1329	393	12	a.	a.	PROPN
ecletica-1329	393	13	;	;	PUNCT
ecletica-1329	393	14	medrasi	medrasi	PROPN
ecletica-1329	393	15	,	,	PUNCT
ecletica-1329	393	16	h.	h.	PROPN
ecletica-1329	393	17	y.	y.	PROPN
ecletica-1329	393	18	;	;	PUNCT
ecletica-1329	393	19	sadek	sadek	PROPN
ecletica-1329	393	20	,	,	PUNCT
ecletica-1329	393	21	k.	k.	PROPN
ecletica-1329	393	22	u.	u.	PROPN
ecletica-1329	393	23	advancements	advancement	NOUN
ecletica-1329	393	24	in	in	ADP
ecletica-1329	393	25	the	the	DET
ecletica-1329	393	26	synthesis	synthesis	NOUN
ecletica-1329	393	27	of	of	ADP
ecletica-1329	393	28	fused	fuse	VERB
ecletica-1329	393	29	tetracyclic	tetracyclic	ADJ
ecletica-1329	393	30	quinoline	quinoline	NOUN
ecletica-1329	393	31	derivatives	derivative	NOUN
ecletica-1329	393	32	.	.	PUNCT
ecletica-1329	394	1	rsc	rsc	PROPN
ecletica-1329	394	2	adv	adv	PROPN
ecletica-1329	394	3	.	.	PROPN
ecletica-1329	394	4	2020	2020	NUM
ecletica-1329	394	5	,	,	PUNCT
ecletica-1329	394	6	10	10	NUM
ecletica-1329	394	7	(	(	PUNCT
ecletica-1329	394	8	34	34	NUM
ecletica-1329	394	9	)	)	PUNCT
ecletica-1329	394	10	,	,	PUNCT
ecletica-1329	394	11	19867–19935	19867–19935	NUM
ecletica-1329	394	12	.	.	PUNCT
ecletica-1329	395	1	https://doi.org/10.1039/d0ra02786c	https://doi.org/10.1039/d0ra02786c	NOUN
ecletica-1329	395	2	morgensztern	morgensztern	NOUN
ecletica-1329	395	3	,	,	PUNCT
ecletica-1329	395	4	d.	d.	PROPN
ecletica-1329	395	5	;	;	PUNCT
ecletica-1329	395	6	ng	ng	PROPN
ecletica-1329	395	7	,	,	PUNCT
ecletica-1329	395	8	s.	s.	PROPN
ecletica-1329	395	9	h.	h.	PROPN
ecletica-1329	395	10	;	;	PUNCT
ecletica-1329	395	11	gao	gao	PROPN
ecletica-1329	395	12	,	,	PUNCT
ecletica-1329	395	13	f.	f.	PROPN
ecletica-1329	395	14	;	;	PUNCT
ecletica-1329	395	15	govindan	govindan	PROPN
ecletica-1329	395	16	.	.	PUNCT
ecletica-1329	396	1	r.	r.	PROPN
ecletica-1329	396	2	trends	trend	NOUN
ecletica-1329	396	3	in	in	ADP
ecletica-1329	396	4	stage	stage	NOUN
ecletica-1329	396	5	distribution	distribution	NOUN
ecletica-1329	396	6	for	for	ADP
ecletica-1329	396	7	patients	patient	NOUN
ecletica-1329	396	8	with	with	ADP
ecletica-1329	396	9	non	non	ADJ
ecletica-1329	396	10	-	-	ADJ
ecletica-1329	396	11	small	small	ADJ
ecletica-1329	396	12	cell	cell	NOUN
ecletica-1329	396	13	lung	lung	NOUN
ecletica-1329	396	14	cancer	cancer	NOUN
ecletica-1329	396	15	:	:	PUNCT
ecletica-1329	396	16	a	a	DET
ecletica-1329	396	17	national	national	ADJ
ecletica-1329	396	18	cancer	cancer	NOUN
ecletica-1329	396	19	database	database	NOUN
ecletica-1329	396	20	survey	survey	NOUN
ecletica-1329	396	21	.	.	PUNCT
ecletica-1329	397	1	j.	j.	PROPN
ecletica-1329	397	2	thorac	thorac	PROPN
ecletica-1329	397	3	.	.	PUNCT
ecletica-1329	398	1	oncol	oncol	ADJ
ecletica-1329	398	2	.	.	PUNCT
ecletica-1329	399	1	2010	2010	NUM
ecletica-1329	399	2	,	,	PUNCT
ecletica-1329	399	3	5	5	NUM
ecletica-1329	399	4	(	(	PUNCT
ecletica-1329	399	5	1	1	NUM
ecletica-1329	399	6	)	)	PUNCT
ecletica-1329	399	7	,	,	PUNCT
ecletica-1329	399	8	29–33	29–33	NUM
ecletica-1329	399	9	.	.	PUNCT
ecletica-1329	400	1	https://doi.org/10.1097/jto.0b013e3181c5920c	https://doi.org/10.1097/jto.0b013e3181c5920c	PROPN
ecletica-1329	400	2	muegge	muegge	PROPN
ecletica-1329	400	3	,	,	PUNCT
ecletica-1329	400	4	i.	i.	PROPN
ecletica-1329	400	5	;	;	PUNCT
ecletica-1329	400	6	rarey	rarey	PROPN
ecletica-1329	400	7	,	,	PUNCT
ecletica-1329	400	8	m.	m.	NOUN
ecletica-1329	400	9	small	small	ADJ
ecletica-1329	400	10	molecule	molecule	NOUN
ecletica-1329	400	11	docking	docking	NOUN
ecletica-1329	400	12	and	and	CCONJ
ecletica-1329	400	13	scoring	scoring	NOUN
ecletica-1329	400	14	.	.	PUNCT
ecletica-1329	401	1	in	in	ADP
ecletica-1329	401	2	computational	computational	ADJ
ecletica-1329	401	3	chemistry	chemistry	NOUN
ecletica-1329	401	4	review	review	NOUN
ecletica-1329	401	5	.	.	PUNCT
ecletica-1329	402	1	lipkowitz	lipkowitz	PROPN
ecletica-1329	402	2	,	,	PUNCT
ecletica-1329	402	3	k.	k.	PROPN
ecletica-1329	402	4	b.	b.	PROPN
ecletica-1329	402	5	,	,	PUNCT
ecletica-1329	402	6	boyd	boyd	PROPN
ecletica-1329	402	7	,	,	PUNCT
ecletica-1329	402	8	d.	d.	PROPN
ecletica-1329	402	9	b.	b.	PROPN
ecletica-1329	402	10	,	,	PUNCT
ecletica-1329	402	11	eds	eds	PROPN
ecletica-1329	402	12	.	.	PUNCT
ecletica-1329	402	13	;	;	PUNCT
ecletica-1329	402	14	wiley	wiley	PROPN
ecletica-1329	402	15	online	online	PROPN
ecletica-1329	402	16	library	library	PROPN
ecletica-1329	402	17	,	,	PUNCT
ecletica-1329	402	18	2001	2001	NUM
ecletica-1329	402	19	;	;	PUNCT
ecletica-1329	402	20	vol	vol	NOUN
ecletica-1329	402	21	.	.	PROPN
ecletica-1329	403	1	17	17	NUM
ecletica-1329	403	2	,	,	PUNCT
ecletica-1329	403	3	1–60	1–60	PROPN
ecletica-1329	403	4	.	.	PUNCT
ecletica-1329	404	1	https://doi.org/10.1002/0471224413.ch1	https://doi.org/10.1002/0471224413.ch1	PROPN
ecletica-1329	404	2	ntie	ntie	PROPN
ecletica-1329	404	3	-	-	PUNCT
ecletica-1329	404	4	kang	kang	PROPN
ecletica-1329	404	5	,	,	PUNCT
ecletica-1329	404	6	f.	f.	PROPN
ecletica-1329	405	1	an	an	PRON
ecletica-1329	405	2	in	in	ADP
ecletica-1329	405	3	silico	silico	NOUN
ecletica-1329	405	4	evaluation	evaluation	NOUN
ecletica-1329	405	5	of	of	ADP
ecletica-1329	405	6	the	the	DET
ecletica-1329	405	7	admet	admet	PROPN
ecletica-1329	405	8	profile	profile	NOUN
ecletica-1329	405	9	of	of	ADP
ecletica-1329	405	10	the	the	DET
ecletica-1329	405	11	streptomedb	streptomedb	NOUN
ecletica-1329	405	12	database	database	NOUN
ecletica-1329	405	13	.	.	PUNCT
ecletica-1329	406	1	springerplus	springerplus	PROPN
ecletica-1329	406	2	2013	2013	NUM
ecletica-1329	406	3	,	,	PUNCT
ecletica-1329	406	4	2	2	NUM
ecletica-1329	406	5	,	,	PUNCT
ecletica-1329	406	6	353	353	NUM
ecletica-1329	406	7	.	.	PUNCT
ecletica-1329	407	1	https://doi.org/10.1186/2193-1801-2-353	https://doi.org/10.1186/2193-1801-2-353	PROPN
ecletica-1329	407	2	oke	oke	PROPN
ecletica-1329	407	3	,	,	PUNCT
ecletica-1329	407	4	a.	a.	NOUN
ecletica-1329	407	5	m.	m.	NOUN
ecletica-1329	407	6	;	;	PUNCT
ecletica-1329	407	7	adelakun	adelakun	PROPN
ecletica-1329	407	8	,	,	PUNCT
ecletica-1329	407	9	a.	a.	NOUN
ecletica-1329	407	10	o.	o.	PROPN
ecletica-1329	407	11	;	;	PUNCT
ecletica-1329	407	12	akintelu	akintelu	PROPN
ecletica-1329	407	13	,	,	PUNCT
ecletica-1329	407	14	s.	s.	PROPN
ecletica-1329	407	15	a.	a.	PROPN
ecletica-1329	407	16	;	;	PUNCT
ecletica-1329	407	17	soetan	soetan	PROPN
ecletica-1329	407	18	,	,	PUNCT
ecletica-1329	407	19	e.	e.	PROPN
ecletica-1329	407	20	a.	a.	PROPN
ecletica-1329	407	21	;	;	PUNCT
ecletica-1329	407	22	oyebamiji	oyebamiji	NOUN
ecletica-1329	407	23	,	,	PUNCT
ecletica-1329	407	24	a.	a.	PROPN
ecletica-1329	407	25	k.	k.	PROPN
ecletica-1329	407	26	;	;	PUNCT
ecletica-1329	407	27	ewemoje	ewemoje	NOUN
ecletica-1329	407	28	,	,	PUNCT
ecletica-1329	407	29	t.	t.	NOUN
ecletica-1329	407	30	a.	a.	NOUN
ecletica-1329	407	31	inhibition	inhibition	NOUN
ecletica-1329	407	32	of	of	ADP
ecletica-1329	407	33	angiotensin	angiotensin	NOUN
ecletica-1329	407	34	converting	convert	VERB
ecletica-1329	407	35	enzyme	enzyme	NOUN
ecletica-1329	407	36	by	by	ADP
ecletica-1329	407	37	phytochemicals	phytochemical	NOUN
ecletica-1329	407	38	in	in	ADP
ecletica-1329	407	39	cucurbita	cucurbita	PROPN
ecletica-1329	407	40	pepo	pepo	PROPN
ecletica-1329	407	41	l.	l.	PROPN
ecletica-1329	407	42	:	:	PUNCT
ecletica-1329	407	43	in	in	ADP
ecletica-1329	407	44	silico	silico	NOUN
ecletica-1329	407	45	approach	approach	NOUN
ecletica-1329	407	46	.	.	PUNCT
ecletica-1329	408	1	pharmacological	pharmacological	ADJ
ecletica-1329	408	2	research	research	NOUN
ecletica-1329	408	3	modern	modern	ADJ
ecletica-1329	408	4	chinese	chinese	ADJ
ecletica-1329	408	5	medicine	medicine	NOUN
ecletica-1329	408	6	.	.	PUNCT
ecletica-1329	409	1	2022	2022	NUM
ecletica-1329	409	2	,	,	PUNCT
ecletica-1329	409	3	4	4	NUM
ecletica-1329	409	4	,	,	PUNCT
ecletica-1329	409	5	100142	100142	NUM
ecletica-1329	409	6	.	.	PUNCT
ecletica-1329	410	1	https://doi.org/10.1016/j.prmcm.2022.100142	https://doi.org/10.1016/j.prmcm.2022.100142	PROPN
ecletica-1329	410	2	opoku	opoku	PROPN
ecletica-1329	410	3	-	-	PUNCT
ecletica-1329	410	4	temeng	temeng	NOUN
ecletica-1329	410	5	,	,	PUNCT
ecletica-1329	410	6	c.	c.	PROPN
ecletica-1329	410	7	;	;	PUNCT
ecletica-1329	410	8	dayal	dayal	PROPN
ecletica-1329	410	9	,	,	PUNCT
ecletica-1329	410	10	n.	n.	NOUN
ecletica-1329	410	11	;	;	PUNCT
ecletica-1329	410	12	sooreshjani	sooreshjani	PROPN
ecletica-1329	410	13	,	,	PUNCT
ecletica-1329	410	14	m.	m.	NOUN
ecletica-1329	410	15	a.	a.	NOUN
ecletica-1329	410	16	;	;	PUNCT
ecletica-1329	410	17	sintim	sintim	PROPN
ecletica-1329	410	18	,	,	PUNCT
ecletica-1329	410	19	h.	h.	PROPN
ecletica-1329	410	20	o.	o.	PROPN
ecletica-1329	411	1	3h	3h	PROPN
ecletica-1329	411	2	-	-	PUNCT
ecletica-1329	411	3	pyrazolo	pyrazolo	NOUN
ecletica-1329	412	1	[	[	X
ecletica-1329	412	2	4	4	NUM
ecletica-1329	412	3	,	,	PUNCT
ecletica-1329	412	4	3	3	NUM
ecletica-1329	412	5	-	-	SYM
ecletica-1329	412	6	f	f	NOUN
ecletica-1329	412	7	]	]	X
ecletica-1329	412	8	quinoline	quinoline	NOUN
ecletica-1329	412	9	haspin	haspin	PROPN
ecletica-1329	412	10	kinase	kinase	PROPN
ecletica-1329	412	11	inhibitors	inhibitor	NOUN
ecletica-1329	412	12	and	and	CCONJ
ecletica-1329	412	13	anticancer	anticancer	NOUN
ecletica-1329	412	14	properties	property	NOUN
ecletica-1329	412	15	.	.	PUNCT
ecletica-1329	413	1	bioorg	bioorg	PROPN
ecletica-1329	413	2	.	.	PUNCT
ecletica-1329	414	1	chem	chem	NOUN
ecletica-1329	414	2	.	.	PUNCT
ecletica-1329	415	1	2018	2018	NUM
ecletica-1329	415	2	,	,	PUNCT
ecletica-1329	415	3	78	78	NUM
ecletica-1329	415	4	,	,	PUNCT
ecletica-1329	415	5	418–426	418–426	NUM
ecletica-1329	415	6	.	.	PUNCT
ecletica-1329	416	1	https://doi.org/10.1016/j.bioorg.2018.03.031	https://doi.org/10.1016/j.bioorg.2018.03.031	PROPN
ecletica-1329	416	2	https://revista.iq.unesp.br/index.php/ecletica	https://revista.iq.unesp.br/index.php/ecletica	PROPN
ecletica-1329	416	3	https://doi.org/10.26850/1678-4618eqj.v48.1.2023.p55-71	https://doi.org/10.26850/1678-4618eqj.v48.1.2023.p55-71	PROPN
ecletica-1329	416	4	https://doi.org/10.1002/ijc.21183	https://doi.org/10.1002/ijc.21183	PROPN
ecletica-1329	416	5	https://doi.org/10.1002/ijc.21183	https://doi.org/10.1002/ijc.21183	PROPN
ecletica-1329	416	6	https://doi.org/10.1002/ijc.21183	https://doi.org/10.1002/ijc.21183	PROPN
ecletica-1329	416	7	https://doi.org/10.1002/ijc.21183	https://doi.org/10.1002/ijc.21183	PROPN
ecletica-1329	416	8	https://doi.org/10.1002/ijc.21183	https://doi.org/10.1002/ijc.21183	PROPN
ecletica-1329	416	9	https://doi.org/10.1007/s10822-006-9087-6	https://doi.org/10.1007/s10822-006-9087-6	NUM
ecletica-1329	416	10	https://doi.org/10.1007/s10822-006-9087-6	https://doi.org/10.1007/s10822-006-9087-6	NUM
ecletica-1329	416	11	https://doi.org/10.1007/s10822-006-9087-6	https://doi.org/10.1007/s10822-006-9087-6	NUM
ecletica-1329	416	12	https://doi.org/10.1007/s10822-006-9087-6	https://doi.org/10.1007/s10822-006-9087-6	NUM
ecletica-1329	416	13	https://doi.org/10.1007/s10822-006-9087-6	https://doi.org/10.1007/s10822-006-9087-6	NUM
ecletica-1329	416	14	https://doi.org/10.1007/s10822-006-9087-6	https://doi.org/10.1007/s10822-006-9087-6	NUM
ecletica-1329	416	15	https://doi.org/10.1016/j.ejmech.2013.02.006	https://doi.org/10.1016/j.ejmech.2013.02.006	ADJ
ecletica-1329	416	16	https://doi.org/10.1016/j.ejmech.2013.02.006	https://doi.org/10.1016/j.ejmech.2013.02.006	ADJ
ecletica-1329	416	17	https://doi.org/10.1016/j.ejmech.2013.02.006	https://doi.org/10.1016/j.ejmech.2013.02.006	ADJ
ecletica-1329	416	18	https://doi.org/10.1016/j.ejmech.2013.02.006	https://doi.org/10.1016/j.ejmech.2013.02.006	ADJ
ecletica-1329	416	19	https://doi.org/10.1016/j.ejmech.2013.02.006	https://doi.org/10.1016/j.ejmech.2013.02.006	ADJ
ecletica-1329	416	20	https://doi.org/10.1002/jhet.3930	https://doi.org/10.1002/jhet.3930	ADJ
ecletica-1329	416	21	https://doi.org/10.1002/jhet.3930	https://doi.org/10.1002/jhet.3930	ADJ
ecletica-1329	416	22	https://doi.org/10.1002/jhet.3930	https://doi.org/10.1002/jhet.3930	PROPN
ecletica-1329	416	23	https://doi.org/10.1002/jhet.3930	https://doi.org/10.1002/jhet.3930	PROPN
ecletica-1329	416	24	https://doi.org/10.1002/jhet.3930	https://doi.org/10.1002/jhet.3930	NOUN
ecletica-1329	416	25	https://doi.org/10.1007/978-1-4939-7899-1_1	https://doi.org/10.1007/978-1-4939-7899-1_1	PROPN
ecletica-1329	416	26	https://doi.org/10.1007/978-1-4939-7899-1_1	https://doi.org/10.1007/978-1-4939-7899-1_1	NOUN
ecletica-1329	417	1	https://doi.org/10.1007/978-1-4939-7899-1_1	https://doi.org/10.1007/978-1-4939-7899-1_1	NOUN
ecletica-1329	418	1	https://doi.org/10.1007/978-1-4939-7899-1_1	https://doi.org/10.1007/978-1-4939-7899-1_1	PROPN
ecletica-1329	419	1	https://doi.org/10.1007/978-1-4939-7899-1_1	https://doi.org/10.1007/978-1-4939-7899-1_1	PROPN
ecletica-1329	419	2	https://doi.org/10.1016/j.ejmech.2010.07.028	https://doi.org/10.1016/j.ejmech.2010.07.028	PROPN
ecletica-1329	419	3	https://doi.org/10.1016/j.ejmech.2010.07.028	https://doi.org/10.1016/j.ejmech.2010.07.028	PROPN
ecletica-1329	419	4	https://doi.org/10.1016/j.ejmech.2010.07.028	https://doi.org/10.1016/j.ejmech.2010.07.028	PROPN
ecletica-1329	419	5	https://doi.org/10.1016/j.ejmech.2010.07.028	https://doi.org/10.1016/j.ejmech.2010.07.028	PROPN
ecletica-1329	419	6	https://doi.org/10.1016/j.ejmech.2010.07.028	https://doi.org/10.1016/j.ejmech.2010.07.028	PROPN
ecletica-1329	419	7	https://doi.org/10.1081/dmr-120001387	https://doi.org/10.1081/dmr-120001387	PROPN
ecletica-1329	419	8	https://doi.org/10.1081/dmr-120001387	https://doi.org/10.1081/dmr-120001387	PROPN
ecletica-1329	419	9	https://doi.org/10.1081/dmr-120001387	https://doi.org/10.1081/dmr-120001387	PROPN
ecletica-1329	419	10	https://doi.org/10.1081/dmr-120001387	https://doi.org/10.1081/dmr-120001387	PROPN
ecletica-1329	419	11	https://doi.org/10.1186/s43088-020-00077-5	https://doi.org/10.1186/s43088-020-00077-5	NUM
ecletica-1329	419	12	https://doi.org/10.1186/s43088-020-00077-5	https://doi.org/10.1186/s43088-020-00077-5	NUM
ecletica-1329	419	13	https://doi.org/10.1186/s43088-020-00077-5	https://doi.org/10.1186/s43088-020-00077-5	NUM
ecletica-1329	419	14	https://doi.org/10.1186/s43088-020-00077-5	https://doi.org/10.1186/s43088-020-00077-5	NUM
ecletica-1329	419	15	https://doi.org/10.1186/s43088-020-00077-5	https://doi.org/10.1186/s43088-020-00077-5	NUM
ecletica-1329	419	16	https://doi.org/10.1186/s43088-020-00077-5	https://doi.org/10.1186/s43088-020-00077-5	NUM
ecletica-1329	419	17	https://doi.org/10.1016/j.jphs.2021.05.004	https://doi.org/10.1016/j.jphs.2021.05.004	ADJ
ecletica-1329	419	18	https://doi.org/10.1016/j.jphs.2021.05.004	https://doi.org/10.1016/j.jphs.2021.05.004	ADJ
ecletica-1329	419	19	https://doi.org/10.1016/j.jphs.2021.05.004	https://doi.org/10.1016/j.jphs.2021.05.004	ADJ
ecletica-1329	419	20	https://doi.org/10.1016/j.jphs.2021.05.004	https://doi.org/10.1016/j.jphs.2021.05.004	ADJ
ecletica-1329	419	21	https://doi.org/10.1016/j.jphs.2021.05.004	https://doi.org/10.1016/j.jphs.2021.05.004	ADJ
ecletica-1329	419	22	https://doi.org/10.1016/j.jphs.2021.05.004	https://doi.org/10.1016/j.jphs.2021.05.004	NOUN
ecletica-1329	419	23	https://doi.org/10.3109/14756366.2012.716056	https://doi.org/10.3109/14756366.2012.716056	PROPN
ecletica-1329	419	24	https://doi.org/10.3109/14756366.2012.716056	https://doi.org/10.3109/14756366.2012.716056	PROPN
ecletica-1329	419	25	https://doi.org/10.3109/14756366.2012.716056	https://doi.org/10.3109/14756366.2012.716056	PROPN
ecletica-1329	420	1	https://doi.org/10.3109/14756366.2012.716056	https://doi.org/10.3109/14756366.2012.716056	PROPN
ecletica-1329	420	2	https://doi.org/10.3109/14756366.2012.716056	https://doi.org/10.3109/14756366.2012.716056	PROPN
ecletica-1329	421	1	https://doi.org/10.3109/14756366.2012.716056	https://doi.org/10.3109/14756366.2012.716056	PROPN
ecletica-1329	421	2	https://doi.org/10.3109/14756366.2012.716056	https://doi.org/10.3109/14756366.2012.716056	PROPN
ecletica-1329	422	1	https://doi.org/10.1016/s0169-409x(00)00129-0	https://doi.org/10.1016/s0169-409x(00)00129-0	PROPN
ecletica-1329	422	2	https://doi.org/10.1016/s0169-409x(00)00129-0	https://doi.org/10.1016/s0169-409x(00)00129-0	PROPN
ecletica-1329	423	1	https://doi.org/10.1016/s0169-409x(00)00129-0	https://doi.org/10.1016/s0169-409x(00)00129-0	PROPN
ecletica-1329	424	1	https://doi.org/10.1016/s0169-409x(00)00129-0	https://doi.org/10.1016/s0169-409x(00)00129-0	PROPN
ecletica-1329	424	2	https://doi.org/10.1016/s0169-409x(00)00129-0	https://doi.org/10.1016/s0169-409x(00)00129-0	PROPN
ecletica-1329	424	3	https://doi.org/10.1007/s10822-009-9268-1	https://doi.org/10.1007/s10822-009-9268-1	PROPN
ecletica-1329	424	4	https://doi.org/10.1007/s10822-009-9268-1	https://doi.org/10.1007/s10822-009-9268-1	NUM
ecletica-1329	424	5	https://doi.org/10.1007/s10822-009-9268-1	https://doi.org/10.1007/s10822-009-9268-1	NOUN
ecletica-1329	424	6	https://doi.org/10.1007/s10822-009-9268-1	https://doi.org/10.1007/s10822-009-9268-1	NOUN
ecletica-1329	424	7	https://doi.org/10.1007/s10822-009-9268-1	https://doi.org/10.1007/s10822-009-9268-1	NOUN
ecletica-1329	424	8	https://doi.org/10.1016/j.bjbas.2017.07.005	https://doi.org/10.1016/j.bjbas.2017.07.005	ADV
ecletica-1329	424	9	https://doi.org/10.1016/j.bjbas.2017.07.005	https://doi.org/10.1016/j.bjbas.2017.07.005	NUM
ecletica-1329	424	10	https://doi.org/10.1016/j.bjbas.2017.07.005	https://doi.org/10.1016/j.bjbas.2017.07.005	NUM
ecletica-1329	424	11	https://doi.org/10.1016/j.bjbas.2017.07.005	https://doi.org/10.1016/j.bjbas.2017.07.005	NUM
ecletica-1329	424	12	https://doi.org/10.1016/j.bjbas.2017.07.005	https://doi.org/10.1016/j.bjbas.2017.07.005	PRON
ecletica-1329	424	13	https://doi.org/10.1039/d0ra02786c	https://doi.org/10.1039/d0ra02786c	PRON
ecletica-1329	424	14	https://doi.org/10.1039/d0ra02786c	https://doi.org/10.1039/d0ra02786c	SYM
ecletica-1329	424	15	https://doi.org/10.1039/d0ra02786c	https://doi.org/10.1039/d0ra02786c	PRON
ecletica-1329	424	16	https://doi.org/10.1039/d0ra02786c	https://doi.org/10.1039/d0ra02786c	NOUN
ecletica-1329	424	17	https://doi.org/10.1097/jto.0b013e3181c5920c	https://doi.org/10.1097/jto.0b013e3181c5920c	NOUN
ecletica-1329	424	18	https://doi.org/10.1097/jto.0b013e3181c5920c	https://doi.org/10.1097/jto.0b013e3181c5920c	NOUN
ecletica-1329	424	19	https://doi.org/10.1097/jto.0b013e3181c5920c	https://doi.org/10.1097/jto.0b013e3181c5920c	NOUN
ecletica-1329	424	20	https://doi.org/10.1097/jto.0b013e3181c5920c	https://doi.org/10.1097/jto.0b013e3181c5920c	NOUN
ecletica-1329	424	21	https://doi.org/10.1002/0471224413.ch1	https://doi.org/10.1002/0471224413.ch1	PROPN
ecletica-1329	424	22	https://doi.org/10.1002/0471224413.ch1	https://doi.org/10.1002/0471224413.ch1	PROPN
ecletica-1329	424	23	https://doi.org/10.1002/0471224413.ch1	https://doi.org/10.1002/0471224413.ch1	PROPN
ecletica-1329	424	24	https://doi.org/10.1002/0471224413.ch1	https://doi.org/10.1002/0471224413.ch1	PROPN
ecletica-1329	424	25	https://doi.org/10.1186/2193-1801-2-353	https://doi.org/10.1186/2193-1801-2-353	PROPN
ecletica-1329	424	26	https://doi.org/10.1186/2193-1801-2-353	https://doi.org/10.1186/2193-1801-2-353	PROPN
ecletica-1329	424	27	https://doi.org/10.1186/2193-1801-2-353	https://doi.org/10.1186/2193-1801-2-353	PROPN
ecletica-1329	424	28	https://doi.org/10.1016/j.prmcm.2022.100142	https://doi.org/10.1016/j.prmcm.2022.100142	PROPN
ecletica-1329	424	29	https://doi.org/10.1016/j.prmcm.2022.100142	https://doi.org/10.1016/j.prmcm.2022.100142	PROPN
ecletica-1329	424	30	https://doi.org/10.1016/j.prmcm.2022.100142	https://doi.org/10.1016/j.prmcm.2022.100142	PROPN
ecletica-1329	424	31	https://doi.org/10.1016/j.prmcm.2022.100142	https://doi.org/10.1016/j.prmcm.2022.100142	PROPN
ecletica-1329	424	32	https://doi.org/10.1016/j.prmcm.2022.100142	https://doi.org/10.1016/j.prmcm.2022.100142	PROPN
ecletica-1329	424	33	https://doi.org/10.1016/j.prmcm.2022.100142	https://doi.org/10.1016/j.prmcm.2022.100142	ADJ
ecletica-1329	424	34	https://doi.org/10.1016/j.bioorg.2018.03.031	https://doi.org/10.1016/j.bioorg.2018.03.031	NOUN
ecletica-1329	425	1	https://doi.org/10.1016/j.bioorg.2018.03.031	https://doi.org/10.1016/j.bioorg.2018.03.031	NOUN
ecletica-1329	425	2	https://doi.org/10.1016/j.bioorg.2018.03.031	https://doi.org/10.1016/j.bioorg.2018.03.031	NOUN
ecletica-1329	425	3	https://doi.org/10.1016/j.bioorg.2018.03.031	https://doi.org/10.1016/j.bioorg.2018.03.031	PROPN
ecletica-1329	425	4	original	original	ADJ
ecletica-1329	425	5	article	article	NOUN
ecletica-1329	425	6	revista.iq.unesp.br	revista.iq.unesp.br	PROPN
ecletica-1329	425	7	70	70	NUM
ecletica-1329	425	8	eclética	eclética	PROPN
ecletica-1329	425	9	química	química	PROPN
ecletica-1329	425	10	,	,	PUNCT
ecletica-1329	425	11	vol	vol	NOUN
ecletica-1329	425	12	.	.	PROPN
ecletica-1329	425	13	48	48	NUM
ecletica-1329	425	14	,	,	PUNCT
ecletica-1329	425	15	n.	n.	NOUN
ecletica-1329	425	16	1	1	NUM
ecletica-1329	425	17	,	,	PUNCT
ecletica-1329	425	18	2023	2023	NUM
ecletica-1329	425	19	,	,	PUNCT
ecletica-1329	425	20	55	55	NUM
ecletica-1329	425	21	-	-	SYM
ecletica-1329	425	22	71	71	NUM
ecletica-1329	425	23	issn	issn	NOUN
ecletica-1329	425	24	:	:	PUNCT
ecletica-1329	425	25	1678	1678	NUM
ecletica-1329	425	26	-	-	SYM
ecletica-1329	425	27	4618	4618	NUM
ecletica-1329	425	28	doi	doi	NOUN
ecletica-1329	425	29	:	:	PUNCT
ecletica-1329	425	30	10.26850/1678	10.26850/1678	NUM
ecletica-1329	425	31	-	-	PUNCT
ecletica-1329	425	32	4618eqj.v48.1.2023.p55	4618eqj.v48.1.2023.p55	NUM
ecletica-1329	425	33	-	-	PUNCT
ecletica-1329	425	34	71	71	NUM
ecletica-1329	425	35	oyebamiji	oyebamiji	NOUN
ecletica-1329	425	36	,	,	PUNCT
ecletica-1329	425	37	a.k	a.k	PROPN
ecletica-1329	425	38	.	.	PROPN
ecletica-1329	425	39	;	;	PUNCT
ecletica-1329	425	40	and	and	CCONJ
ecletica-1329	425	41	semire	semire	NOUN
ecletica-1329	425	42	,	,	PUNCT
ecletica-1329	425	43	b.	b.	PROPN
ecletica-1329	425	44	theoretical	theoretical	ADJ
ecletica-1329	425	45	studies	study	NOUN
ecletica-1329	425	46	of	of	ADP
ecletica-1329	425	47	anticorrosion	anticorrosion	NOUN
ecletica-1329	425	48	properties	property	NOUN
ecletica-1329	425	49	of	of	ADP
ecletica-1329	425	50	triphenylimidazole	triphenylimidazole	NOUN
ecletica-1329	425	51	derivatives	derivative	NOUN
ecletica-1329	425	52	in	in	ADP
ecletica-1329	425	53	corrosion	corrosion	NOUN
ecletica-1329	425	54	inhibition	inhibition	NOUN
ecletica-1329	425	55	of	of	ADP
ecletica-1329	425	56	carbon	carbon	NOUN
ecletica-1329	425	57	steel	steel	NOUN
ecletica-1329	425	58	in	in	ADP
ecletica-1329	425	59	acidic	acidic	ADJ
ecletica-1329	425	60	media	medium	NOUN
ecletica-1329	425	61	via	via	ADP
ecletica-1329	425	62	dft	dft	PROPN
ecletica-1329	425	63	approach	approach	NOUN
ecletica-1329	425	64	.	.	PUNCT
ecletica-1329	426	1	anal	anal	ADJ
ecletica-1329	426	2	.	.	PUNCT
ecletica-1329	427	1	bioanal	bioanal	PROPN
ecletica-1329	427	2	.	.	PUNCT
ecletica-1329	428	1	electrochem	electrochem	PROPN
ecletica-1329	428	2	.	.	PUNCT
ecletica-1329	429	1	2018	2018	NUM
ecletica-1329	429	2	,	,	PUNCT
ecletica-1329	429	3	10	10	NUM
ecletica-1329	429	4	(	(	PUNCT
ecletica-1329	429	5	1	1	NUM
ecletica-1329	429	6	)	)	PUNCT
ecletica-1329	429	7	,	,	PUNCT
ecletica-1329	429	8	136–146	136–146	NUM
ecletica-1329	429	9	.	.	PUNCT
ecletica-1329	429	10	oyebamiji	oyebamiji	PROPN
ecletica-1329	429	11	,	,	PUNCT
ecletica-1329	429	12	a.	a.	PROPN
ecletica-1329	429	13	k.	k.	PROPN
ecletica-1329	429	14	;	;	PUNCT
ecletica-1329	429	15	fadare	fadare	VERB
ecletica-1329	429	16	,	,	PUNCT
ecletica-1329	429	17	o.	o.	NOUN
ecletica-1329	429	18	a.	a.	NOUN
ecletica-1329	429	19	;	;	PUNCT
ecletica-1329	430	1	akintelu	akintelu	ADV
ecletica-1329	430	2	,	,	PUNCT
ecletica-1329	430	3	s.	s.	PROPN
ecletica-1329	430	4	a	a	PRON
ecletica-1329	430	5	;	;	PUNCT
ecletica-1329	430	6	semire	semire	NOUN
ecletica-1329	430	7	,	,	PUNCT
ecletica-1329	430	8	b.	b.	PROPN
ecletica-1329	430	9	biological	biological	ADJ
ecletica-1329	430	10	studies	study	NOUN
ecletica-1329	430	11	on	on	ADP
ecletica-1329	430	12	anthra[1,9	anthra[1,9	PROPN
ecletica-1329	430	13	-	-	PUNCT
ecletica-1329	430	14	cd]pyrazol-6(2d)-one	cd]pyrazol-6(2d)-one	NUM
ecletica-1329	430	15	analogues	analogue	NOUN
ecletica-1329	430	16	as	as	ADP
ecletica-1329	430	17	anti	anti	ADJ
ecletica-1329	430	18	-	-	ADJ
ecletica-1329	430	19	vascular	vascular	ADJ
ecletica-1329	430	20	endothelial	endothelial	ADJ
ecletica-1329	430	21	growth	growth	NOUN
ecletica-1329	430	22	factor	factor	NOUN
ecletica-1329	430	23	via	via	ADP
ecletica-1329	430	24	in	in	ADP
ecletica-1329	430	25	silico	silico	NOUN
ecletica-1329	430	26	mechanisms	mechanism	NOUN
ecletica-1329	430	27	.	.	PUNCT
ecletica-1329	431	1	chemistry	chemistry	PROPN
ecletica-1329	431	2	africa	africa	PROPN
ecletica-1329	431	3	2021	2021	NUM
ecletica-1329	431	4	,	,	PUNCT
ecletica-1329	431	5	4	4	NUM
ecletica-1329	431	6	(	(	PUNCT
ecletica-1329	431	7	4	4	NUM
ecletica-1329	431	8	)	)	PUNCT
ecletica-1329	431	9	,	,	PUNCT
ecletica-1329	431	10	955–963	955–963	NUM
ecletica-1329	431	11	.	.	PUNCT
ecletica-1329	432	1	https://doi.org/10.1007/s42250-021-00276-2	https://doi.org/10.1007/s42250-021-00276-2	NUM
ecletica-1329	432	2	oyeneyin	oyeneyin	NOUN
ecletica-1329	432	3	,	,	PUNCT
ecletica-1329	432	4	o.	o.	PROPN
ecletica-1329	432	5	e.	e.	PROPN
ecletica-1329	432	6	;	;	PUNCT
ecletica-1329	432	7	iwegbulam	iwegbulam	PROPN
ecletica-1329	432	8	,	,	PUNCT
ecletica-1329	432	9	c.	c.	PROPN
ecletica-1329	432	10	g.	g.	PROPN
ecletica-1329	432	11	;	;	PUNCT
ecletica-1329	433	1	ipinloju	ipinloju	NOUN
ecletica-1329	433	2	,	,	PUNCT
ecletica-1329	433	3	n.	n.	NOUN
ecletica-1329	433	4	;	;	PUNCT
ecletica-1329	433	5	olajide	olajide	PROPN
ecletica-1329	433	6	,	,	PUNCT
ecletica-1329	433	7	b.	b.	PROPN
ecletica-1329	433	8	f.	f.	PROPN
ecletica-1329	433	9	;	;	PUNCT
ecletica-1329	433	10	oyebamiji	oyebamiji	PROPN
ecletica-1329	433	11	,	,	PUNCT
ecletica-1329	433	12	a.	a.	NOUN
ecletica-1329	433	13	k.	k.	PROPN
ecletica-1329	433	14	prediction	prediction	NOUN
ecletica-1329	433	15	of	of	ADP
ecletica-1329	433	16	the	the	DET
ecletica-1329	433	17	antiproliferative	antiproliferative	ADJ
ecletica-1329	433	18	effects	effect	NOUN
ecletica-1329	433	19	of	of	ADP
ecletica-1329	433	20	some	some	DET
ecletica-1329	433	21	benzimidazolechalcone	benzimidazolechalcone	NOUN
ecletica-1329	433	22	derivatives	derivative	NOUN
ecletica-1329	433	23	against	against	ADP
ecletica-1329	433	24	mcf-7	mcf-7	NOUN
ecletica-1329	433	25	breast	breast	NOUN
ecletica-1329	433	26	cancer	cancer	NOUN
ecletica-1329	433	27	cell	cell	NOUN
ecletica-1329	433	28	lines	line	NOUN
ecletica-1329	433	29	:	:	PUNCT
ecletica-1329	433	30	qsar	qsar	NOUN
ecletica-1329	433	31	and	and	CCONJ
ecletica-1329	433	32	molecular	molecular	ADJ
ecletica-1329	433	33	docking	docking	NOUN
ecletica-1329	433	34	studies	study	NOUN
ecletica-1329	433	35	.	.	PUNCT
ecletica-1329	434	1	org	org	NOUN
ecletica-1329	434	2	.	.	PUNCT
ecletica-1329	434	3	commun	commun	PROPN
ecletica-1329	434	4	.	.	PUNCT
ecletica-1329	435	1	2022	2022	NUM
ecletica-1329	435	2	,	,	PUNCT
ecletica-1329	435	3	15	15	NUM
ecletica-1329	435	4	(	(	PUNCT
ecletica-1329	435	5	3	3	NUM
ecletica-1329	435	6	)	)	PUNCT
ecletica-1329	435	7	,	,	PUNCT
ecletica-1329	435	8	273–287	273–287	NUM
ecletica-1329	435	9	.	.	PUNCT
ecletica-1329	436	1	https://doi.org/10.25135/acg.oc.132.2203	https://doi.org/10.25135/acg.oc.132.2203	PROPN
ecletica-1329	436	2	parr	parr	PROPN
ecletica-1329	436	3	,	,	PUNCT
ecletica-1329	436	4	r.	r.	PROPN
ecletica-1329	436	5	g.	g.	PROPN
ecletica-1329	436	6	;	;	PUNCT
ecletica-1329	436	7	szentpály	szentpály	PROPN
ecletica-1329	436	8	,	,	PUNCT
ecletica-1329	436	9	l.	l.	PROPN
ecletica-1329	436	10	;	;	PUNCT
ecletica-1329	436	11	liu	liu	PROPN
ecletica-1329	436	12	,	,	PUNCT
ecletica-1329	436	13	s.	s.	PROPN
ecletica-1329	436	14	electrophilicity	electrophilicity	PROPN
ecletica-1329	436	15	index	index	PROPN
ecletica-1329	436	16	.	.	PUNCT
ecletica-1329	437	1	j.	j.	PROPN
ecletica-1329	437	2	am	am	PROPN
ecletica-1329	437	3	.	.	PUNCT
ecletica-1329	438	1	chem	chem	NOUN
ecletica-1329	438	2	.	.	PUNCT
ecletica-1329	439	1	soc	soc	PROPN
ecletica-1329	439	2	.	.	PUNCT
ecletica-1329	440	1	1999	1999	NUM
ecletica-1329	440	2	,	,	PUNCT
ecletica-1329	440	3	121	121	NUM
ecletica-1329	440	4	(	(	PUNCT
ecletica-1329	440	5	9	9	NUM
ecletica-1329	440	6	)	)	PUNCT
ecletica-1329	440	7	,	,	PUNCT
ecletica-1329	440	8	1922–1924	1922–1924	NUM
ecletica-1329	440	9	.	.	PUNCT
ecletica-1329	441	1	https://doi.org/10.1021/ja983494x	https://doi.org/10.1021/ja983494x	PROPN
ecletica-1329	441	2	pettersen	pettersen	PROPN
ecletica-1329	441	3	,	,	PUNCT
ecletica-1329	441	4	e.	e.	PROPN
ecletica-1329	441	5	f.	f.	PROPN
ecletica-1329	441	6	;	;	PUNCT
ecletica-1329	441	7	goddard	goddard	PROPN
ecletica-1329	441	8	,	,	PUNCT
ecletica-1329	441	9	t.	t.	PROPN
ecletica-1329	441	10	d.	d.	PROPN
ecletica-1329	441	11	;	;	PUNCT
ecletica-1329	441	12	huang	huang	PROPN
ecletica-1329	441	13	,	,	PUNCT
ecletica-1329	441	14	c.	c.	PROPN
ecletica-1329	441	15	c.	c.	PROPN
ecletica-1329	441	16	;	;	PUNCT
ecletica-1329	441	17	couch	couch	NOUN
ecletica-1329	441	18	,	,	PUNCT
ecletica-1329	441	19	g.	g.	PROPN
ecletica-1329	441	20	s.	s.	PROPN
ecletica-1329	441	21	;	;	PUNCT
ecletica-1329	441	22	greenblatt	greenblatt	PROPN
ecletica-1329	441	23	,	,	PUNCT
ecletica-1329	441	24	d.	d.	PROPN
ecletica-1329	441	25	m.	m.	PROPN
ecletica-1329	441	26	;	;	PUNCT
ecletica-1329	441	27	meng	meng	PROPN
ecletica-1329	441	28	,	,	PUNCT
ecletica-1329	441	29	e.	e.	PROPN
ecletica-1329	441	30	c.	c.	PROPN
ecletica-1329	441	31	;	;	PUNCT
ecletica-1329	441	32	ferrin	ferrin	NOUN
ecletica-1329	441	33	,	,	PUNCT
ecletica-1329	441	34	t.	t.	PROPN
ecletica-1329	441	35	e.	e.	PROPN
ecletica-1329	441	36	ucsf	ucsf	PROPN
ecletica-1329	441	37	chimera	chimera	PROPN
ecletica-1329	441	38	—	—	PUNCT
ecletica-1329	441	39	a	a	DET
ecletica-1329	441	40	visualization	visualization	NOUN
ecletica-1329	441	41	system	system	NOUN
ecletica-1329	441	42	for	for	ADP
ecletica-1329	441	43	exploratory	exploratory	ADJ
ecletica-1329	441	44	research	research	NOUN
ecletica-1329	441	45	and	and	CCONJ
ecletica-1329	441	46	analysis	analysis	NOUN
ecletica-1329	441	47	.	.	PUNCT
ecletica-1329	442	1	j.	j.	PROPN
ecletica-1329	442	2	comput	comput	PROPN
ecletica-1329	442	3	.	.	PUNCT
ecletica-1329	443	1	chem	chem	PROPN
ecletica-1329	443	2	.	.	PUNCT
ecletica-1329	444	1	2004	2004	NUM
ecletica-1329	444	2	,	,	PUNCT
ecletica-1329	444	3	25	25	NUM
ecletica-1329	444	4	(	(	PUNCT
ecletica-1329	444	5	13	13	NUM
ecletica-1329	444	6	)	)	PUNCT
ecletica-1329	444	7	,	,	PUNCT
ecletica-1329	444	8	1605–1612	1605–1612	NUM
ecletica-1329	444	9	.	.	PUNCT
ecletica-1329	445	1	https://doi.org/10.1002/jcc.20084	https://doi.org/10.1002/jcc.20084	PROPN
ecletica-1329	445	2	puzyn	puzyn	PROPN
ecletica-1329	445	3	,	,	PUNCT
ecletica-1329	445	4	t.	t.	PROPN
ecletica-1329	445	5	;	;	PUNCT
ecletica-1329	445	6	leszczynski	leszczynski	PROPN
ecletica-1329	445	7	,	,	PUNCT
ecletica-1329	445	8	j.	j.	PROPN
ecletica-1329	445	9	;	;	PUNCT
ecletica-1329	445	10	cronin	cronin	PROPN
ecletica-1329	445	11	,	,	PUNCT
ecletica-1329	445	12	m.	m.	NOUN
ecletica-1329	445	13	recent	recent	ADJ
ecletica-1329	445	14	advances	advance	NOUN
ecletica-1329	445	15	in	in	ADP
ecletica-1329	445	16	qsar	qsar	NOUN
ecletica-1329	445	17	studies	study	NOUN
ecletica-1329	445	18	:	:	PUNCT
ecletica-1329	445	19	methods	method	NOUN
ecletica-1329	445	20	and	and	CCONJ
ecletica-1329	445	21	applications	application	NOUN
ecletica-1329	445	22	,	,	PUNCT
ecletica-1329	445	23	vol	vol	NOUN
ecletica-1329	445	24	.	.	PROPN
ecletica-1329	445	25	8	8	NUM
ecletica-1329	445	26	;	;	PUNCT
ecletica-1329	445	27	springer	springer	NOUN
ecletica-1329	445	28	dordrecht	dordrecht	PROPN
ecletica-1329	445	29	,	,	PUNCT
ecletica-1329	445	30	2010	2010	NUM
ecletica-1329	445	31	.	.	PUNCT
ecletica-1329	446	1	https://doi.org/10.1007/978-1-4020-9783-6	https://doi.org/10.1007/978-1-4020-9783-6	PROPN
ecletica-1329	446	2	sahin	sahin	PROPN
ecletica-1329	446	3	,	,	PUNCT
ecletica-1329	446	4	s.	s.	PROPN
ecletica-1329	446	5	;	;	PUNCT
ecletica-1329	446	6	benet	benet	PROPN
ecletica-1329	446	7	,	,	PUNCT
ecletica-1329	446	8	l.	l.	PROPN
ecletica-1329	446	9	z.	z.	PROPN
ecletica-1329	447	1	the	the	DET
ecletica-1329	447	2	operational	operational	ADJ
ecletica-1329	447	3	multiple	multiple	ADJ
ecletica-1329	447	4	dosing	dose	VERB
ecletica-1329	447	5	halflife	halflife	NOUN
ecletica-1329	447	6	:	:	PUNCT
ecletica-1329	447	7	a	a	DET
ecletica-1329	447	8	key	key	NOUN
ecletica-1329	447	9	to	to	ADP
ecletica-1329	447	10	defining	define	VERB
ecletica-1329	447	11	drug	drug	NOUN
ecletica-1329	447	12	accumulation	accumulation	NOUN
ecletica-1329	447	13	in	in	ADP
ecletica-1329	447	14	patients	patient	NOUN
ecletica-1329	447	15	and	and	CCONJ
ecletica-1329	447	16	to	to	ADP
ecletica-1329	447	17	designing	design	VERB
ecletica-1329	447	18	extended	extend	VERB
ecletica-1329	447	19	-	-	PUNCT
ecletica-1329	447	20	release	release	NOUN
ecletica-1329	447	21	dosage	dosage	NOUN
ecletica-1329	447	22	forms	form	NOUN
ecletica-1329	447	23	.	.	PUNCT
ecletica-1329	448	1	pharm	pharm	NOUN
ecletica-1329	448	2	.	.	PUNCT
ecletica-1329	449	1	res	re	NOUN
ecletica-1329	449	2	.	.	PROPN
ecletica-1329	449	3	2008	2008	NUM
ecletica-1329	449	4	,	,	PUNCT
ecletica-1329	449	5	25	25	NUM
ecletica-1329	449	6	(	(	PUNCT
ecletica-1329	449	7	12	12	NUM
ecletica-1329	449	8	)	)	PUNCT
ecletica-1329	449	9	,	,	PUNCT
ecletica-1329	449	10	2869–2877	2869–2877	NUM
ecletica-1329	449	11	.	.	PUNCT
ecletica-1329	450	1	https://doi.org/10.1007/s11095-0089787-9	https://doi.org/10.1007/s11095-0089787-9	PROPN
ecletica-1329	450	2	salim	salim	PROPN
ecletica-1329	450	3	,	,	PUNCT
ecletica-1329	450	4	e.	e.	PROPN
ecletica-1329	450	5	i.	i.	PROPN
ecletica-1329	450	6	;	;	PUNCT
ecletica-1329	450	7	jazieh	jazieh	PROPN
ecletica-1329	450	8	,	,	PUNCT
ecletica-1329	450	9	a.	a.	PROPN
ecletica-1329	450	10	r.	r.	PROPN
ecletica-1329	450	11	;	;	PUNCT
ecletica-1329	450	12	moore	moore	PROPN
ecletica-1329	450	13	,	,	PUNCT
ecletica-1329	450	14	m.	m.	NOUN
ecletica-1329	450	15	a.	a.	NOUN
ecletica-1329	450	16	lung	lung	PROPN
ecletica-1329	450	17	cancer	cancer	NOUN
ecletica-1329	450	18	incidence	incidence	NOUN
ecletica-1329	450	19	in	in	ADP
ecletica-1329	450	20	the	the	DET
ecletica-1329	450	21	arab	arab	PROPN
ecletica-1329	450	22	league	league	PROPN
ecletica-1329	450	23	countries	country	NOUN
ecletica-1329	450	24	:	:	PUNCT
ecletica-1329	450	25	risk	risk	NOUN
ecletica-1329	450	26	factors	factor	NOUN
ecletica-1329	450	27	and	and	CCONJ
ecletica-1329	450	28	control	control	NOUN
ecletica-1329	450	29	.	.	PUNCT
ecletica-1329	451	1	asian	asian	PROPN
ecletica-1329	451	2	pacific	pacific	PROPN
ecletica-1329	451	3	j.	j.	PROPN
ecletica-1329	451	4	cancer	cancer	PROPN
ecletica-1329	451	5	prev	prev	PROPN
ecletica-1329	451	6	.	.	PUNCT
ecletica-1329	452	1	2011	2011	NUM
ecletica-1329	452	2	,	,	PUNCT
ecletica-1329	452	3	12	12	NUM
ecletica-1329	452	4	(	(	PUNCT
ecletica-1329	452	5	1	1	NUM
ecletica-1329	452	6	)	)	PUNCT
ecletica-1329	452	7	,	,	PUNCT
ecletica-1329	452	8	17–34	17–34	NUM
ecletica-1329	452	9	.	.	PUNCT
ecletica-1329	453	1	sato	sato	PROPN
ecletica-1329	453	2	,	,	PUNCT
ecletica-1329	453	3	t.	t.	PROPN
ecletica-1329	453	4	;	;	PUNCT
ecletica-1329	453	5	watanabe	watanabe	PROPN
ecletica-1329	453	6	,	,	PUNCT
ecletica-1329	453	7	h.	h.	PROPN
ecletica-1329	453	8	;	;	PUNCT
ecletica-1329	453	9	tsuganezawa	tsuganezawa	PROPN
ecletica-1329	453	10	,	,	PUNCT
ecletica-1329	453	11	k.	k.	PROPN
ecletica-1329	453	12	;	;	PUNCT
ecletica-1329	453	13	yuki	yuki	PROPN
ecletica-1329	453	14	,	,	PUNCT
ecletica-1329	453	15	h.	h.	PROPN
ecletica-1329	453	16	;	;	PUNCT
ecletica-1329	453	17	mikuni	mikuni	PROPN
ecletica-1329	453	18	,	,	PUNCT
ecletica-1329	453	19	j.	j.	PROPN
ecletica-1329	453	20	;	;	PUNCT
ecletica-1329	453	21	yoshikawa	yoshikawa	PROPN
ecletica-1329	453	22	,	,	PUNCT
ecletica-1329	453	23	s.	s.	PROPN
ecletica-1329	453	24	;	;	PUNCT
ecletica-1329	453	25	kukimoto	kukimoto	NOUN
ecletica-1329	453	26	-	-	PUNCT
ecletica-1329	453	27	niino	niino	PROPN
ecletica-1329	453	28	,	,	PUNCT
ecletica-1329	453	29	m.	m.	NOUN
ecletica-1329	453	30	;	;	PUNCT
ecletica-1329	453	31	fujimoto	fujimoto	PROPN
ecletica-1329	453	32	,	,	PUNCT
ecletica-1329	453	33	t.	t.	PROPN
ecletica-1329	453	34	;	;	PUNCT
ecletica-1329	453	35	wakiyama	wakiyama	NOUN
ecletica-1329	453	36	,	,	PUNCT
ecletica-1329	453	37	t.	t.	PROPN
ecletica-1329	453	38	y.	y.	PROPN
ecletica-1329	453	39	;	;	PUNCT
ecletica-1329	453	40	kojim	kojim	PROPN
ecletica-1329	453	41	,	,	PUNCT
ecletica-1329	453	42	h.	h.	PROPN
ecletica-1329	453	43	;	;	PUNCT
ecletica-1329	453	44	okabe	okabe	PROPN
ecletica-1329	453	45	,	,	PUNCT
ecletica-1329	453	46	t.	t.	PROPN
ecletica-1329	453	47	;	;	PUNCT
ecletica-1329	453	48	nagano	nagano	PROPN
ecletica-1329	453	49	,	,	PUNCT
ecletica-1329	453	50	t.	t.	PROPN
ecletica-1329	453	51	;	;	PUNCT
ecletica-1329	453	52	shirouzu	shirouzu	ADJ
ecletica-1329	453	53	,	,	PUNCT
ecletica-1329	453	54	m.	m.	NOUN
ecletica-1329	453	55	;	;	PUNCT
ecletica-1329	453	56	yokoyama	yokoyama	PROPN
ecletica-1329	453	57	,	,	PUNCT
ecletica-1329	453	58	s.	s.	PROPN
ecletica-1329	453	59	;	;	PUNCT
ecletica-1329	453	60	tanaka	tanaka	PROPN
ecletica-1329	453	61	,	,	PUNCT
ecletica-1329	453	62	a.	a.	NOUN
ecletica-1329	453	63	;	;	PUNCT
ecletica-1329	453	64	honma	honma	PROPN
ecletica-1329	453	65	,	,	PUNCT
ecletica-1329	453	66	t.	t.	NOUN
ecletica-1329	453	67	identification	identification	NOUN
ecletica-1329	453	68	of	of	ADP
ecletica-1329	453	69	novel	novel	ADJ
ecletica-1329	453	70	drug	drug	NOUN
ecletica-1329	453	71	-	-	PUNCT
ecletica-1329	453	72	resistant	resistant	ADJ
ecletica-1329	453	73	egfr	egfr	ADJ
ecletica-1329	453	74	mutant	mutant	ADJ
ecletica-1329	453	75	inhibitors	inhibitor	NOUN
ecletica-1329	453	76	by	by	ADP
ecletica-1329	453	77	in	in	ADP
ecletica-1329	453	78	silico	silico	NOUN
ecletica-1329	453	79	screening	screen	VERB
ecletica-1329	453	80	using	use	VERB
ecletica-1329	453	81	comprehensive	comprehensive	ADJ
ecletica-1329	453	82	assessments	assessment	NOUN
ecletica-1329	453	83	of	of	ADP
ecletica-1329	453	84	protein	protein	NOUN
ecletica-1329	453	85	structures	structure	NOUN
ecletica-1329	453	86	.	.	PUNCT
ecletica-1329	454	1	bioorg	bioorg	VERB
ecletica-1329	454	2	.	.	PUNCT
ecletica-1329	455	1	med	med	PROPN
ecletica-1329	455	2	.	.	PROPN
ecletica-1329	455	3	chem	chem	PROPN
ecletica-1329	455	4	.	.	PUNCT
ecletica-1329	456	1	2012	2012	NUM
ecletica-1329	456	2	,	,	PUNCT
ecletica-1329	456	3	20	20	NUM
ecletica-1329	456	4	(	(	PUNCT
ecletica-1329	456	5	12	12	NUM
ecletica-1329	456	6	)	)	PUNCT
ecletica-1329	456	7	,	,	PUNCT
ecletica-1329	456	8	3756	3756	NUM
ecletica-1329	456	9	–	–	PUNCT
ecletica-1329	456	10	3767	3767	NUM
ecletica-1329	456	11	.	.	PUNCT
ecletica-1329	457	1	https://doi.org/10.1016/j.bmc.2012.04.042	https://doi.org/10.1016/j.bmc.2012.04.042	PROPN
ecletica-1329	457	2	semire	semire	NOUN
ecletica-1329	457	3	,	,	PUNCT
ecletica-1329	457	4	b.	b.	PROPN
ecletica-1329	457	5	;	;	PUNCT
ecletica-1329	457	6	mutiu	mutiu	NOUN
ecletica-1329	457	7	,	,	PUNCT
ecletica-1329	457	8	o.	o.	PROPN
ecletica-1329	457	9	a.	a.	PROPN
ecletica-1329	457	10	;	;	PUNCT
ecletica-1329	457	11	oyebamiji	oyebamiji	NOUN
ecletica-1329	457	12	,	,	PUNCT
ecletica-1329	457	13	a.	a.	PROPN
ecletica-1329	457	14	k.	k.	PROPN
ecletica-1329	457	15	dft	dft	PROPN
ecletica-1329	457	16	and	and	CCONJ
ecletica-1329	457	17	ab	ab	PROPN
ecletica-1329	457	18	initio	initio	NOUN
ecletica-1329	457	19	methods	method	NOUN
ecletica-1329	457	20	on	on	ADP
ecletica-1329	457	21	nmr	nmr	NOUN
ecletica-1329	457	22	,	,	PUNCT
ecletica-1329	457	23	ir	ir	NOUN
ecletica-1329	457	24	and	and	CCONJ
ecletica-1329	457	25	reactivity	reactivity	NOUN
ecletica-1329	457	26	indices	index	NOUN
ecletica-1329	457	27	of	of	ADP
ecletica-1329	457	28	indol3	indol3	NOUN
ecletica-1329	457	29	-	-	PUNCT
ecletica-1329	457	30	carboxylate	carboxylate	NOUN
ecletica-1329	457	31	and	and	CCONJ
ecletica-1329	457	32	indazole-3	indazole-3	NUM
ecletica-1329	457	33	-	-	PUNCT
ecletica-1329	457	34	carboxylate	carboxylate	NOUN
ecletica-1329	457	35	derivatives	derivative	NOUN
ecletica-1329	457	36	of	of	ADP
ecletica-1329	457	37	cannabinoids	cannabinoid	NOUN
ecletica-1329	457	38	:	:	PUNCT
ecletica-1329	457	39	comparative	comparative	ADJ
ecletica-1329	457	40	study	study	NOUN
ecletica-1329	457	41	.	.	PUNCT
ecletica-1329	458	1	j.	j.	PROPN
ecletica-1329	458	2	phys	phys	PROPN
ecletica-1329	458	3	.	.	PUNCT
ecletica-1329	459	1	theor	theor	PROPN
ecletica-1329	459	2	.	.	PUNCT
ecletica-1329	459	3	chem	chem	PROPN
ecletica-1329	459	4	.	.	PUNCT
ecletica-1329	460	1	2017	2017	NUM
ecletica-1329	460	2	,	,	PUNCT
ecletica-1329	460	3	13	13	NUM
ecletica-1329	460	4	(	(	PUNCT
ecletica-1329	460	5	4	4	NUM
ecletica-1329	460	6	)	)	PUNCT
ecletica-1329	460	7	,	,	PUNCT
ecletica-1329	460	8	353–377	353–377	NUM
ecletica-1329	460	9	.	.	PUNCT
ecletica-1329	460	10	siegel	siegel	PROPN
ecletica-1329	460	11	,	,	PUNCT
ecletica-1329	460	12	r.	r.	PROPN
ecletica-1329	460	13	l.	l.	PROPN
ecletica-1329	460	14	;	;	PUNCT
ecletica-1329	460	15	miller	miller	PROPN
ecletica-1329	460	16	,	,	PUNCT
ecletica-1329	460	17	k.	k.	PROPN
ecletica-1329	460	18	d.	d.	PROPN
ecletica-1329	460	19	;	;	PUNCT
ecletica-1329	460	20	jemal	jemal	ADJ
ecletica-1329	460	21	,	,	PUNCT
ecletica-1329	460	22	a.	a.	NOUN
ecletica-1329	460	23	cancer	cancer	NOUN
ecletica-1329	460	24	statistics	statistic	NOUN
ecletica-1329	460	25	,	,	PUNCT
ecletica-1329	460	26	2016	2016	NUM
ecletica-1329	460	27	.	.	PUNCT
ecletica-1329	461	1	ca	ca	NOUN
ecletica-1329	461	2	:	:	PUNCT
ecletica-1329	461	3	cancer	cancer	NOUN
ecletica-1329	461	4	.	.	PUNCT
ecletica-1329	462	1	j.	j.	PROPN
ecletica-1329	462	2	clin	clin	PROPN
ecletica-1329	462	3	.	.	PUNCT
ecletica-1329	463	1	2016	2016	NUM
ecletica-1329	463	2	,	,	PUNCT
ecletica-1329	463	3	66	66	NUM
ecletica-1329	463	4	(	(	PUNCT
ecletica-1329	463	5	1	1	NUM
ecletica-1329	463	6	)	)	PUNCT
ecletica-1329	463	7	,	,	PUNCT
ecletica-1329	463	8	7–30	7–30	NOUN
ecletica-1329	463	9	.	.	PUNCT
ecletica-1329	464	1	https://doi.org/10.3322/caac.21332	https://doi.org/10.3322/caac.21332	PROPN
ecletica-1329	464	2	stella	stella	PROPN
ecletica-1329	464	3	,	,	PUNCT
ecletica-1329	464	4	g.	g.	PROPN
ecletica-1329	464	5	m.	m.	PROPN
ecletica-1329	464	6	;	;	PUNCT
ecletica-1329	464	7	luisetti	luisetti	NUM
ecletica-1329	464	8	,	,	PUNCT
ecletica-1329	464	9	m.	m.	NOUN
ecletica-1329	464	10	;	;	PUNCT
ecletica-1329	464	11	inghilleri	inghilleri	PROPN
ecletica-1329	464	12	,	,	PUNCT
ecletica-1329	464	13	s.	s.	PROPN
ecletica-1329	464	14	;	;	PUNCT
ecletica-1329	464	15	cemmi	cemmi	PROPN
ecletica-1329	464	16	,	,	PUNCT
ecletica-1329	464	17	f.	f.	PROPN
ecletica-1329	464	18	;	;	PUNCT
ecletica-1329	464	19	scabini	scabini	PROPN
ecletica-1329	464	20	,	,	PUNCT
ecletica-1329	464	21	r.	r.	PROPN
ecletica-1329	464	22	;	;	PUNCT
ecletica-1329	464	23	zorzetto	zorzetto	NOUN
ecletica-1329	464	24	,	,	PUNCT
ecletica-1329	464	25	m.	m.	NOUN
ecletica-1329	464	26	;	;	PUNCT
ecletica-1329	464	27	pozzi	pozzi	PROPN
ecletica-1329	464	28	,	,	PUNCT
ecletica-1329	464	29	e.	e.	PROPN
ecletica-1329	464	30	targeting	target	VERB
ecletica-1329	464	31	egfr	egfr	NOUN
ecletica-1329	464	32	in	in	ADP
ecletica-1329	464	33	non	non	ADJ
ecletica-1329	464	34	-	-	ADJ
ecletica-1329	464	35	small	small	ADJ
ecletica-1329	464	36	-	-	PUNCT
ecletica-1329	464	37	cell	cell	NOUN
ecletica-1329	464	38	lung	lung	NOUN
ecletica-1329	464	39	cancer	cancer	NOUN
ecletica-1329	464	40	:	:	PUNCT
ecletica-1329	464	41	lessons	lesson	NOUN
ecletica-1329	464	42	,	,	PUNCT
ecletica-1329	464	43	experiences	experience	NOUN
ecletica-1329	464	44	,	,	PUNCT
ecletica-1329	464	45	strategies	strategy	NOUN
ecletica-1329	464	46	.	.	PUNCT
ecletica-1329	465	1	respiratory	respiratory	ADJ
ecletica-1329	465	2	medicine	medicine	NOUN
ecletica-1329	465	3	2012	2012	NUM
ecletica-1329	465	4	,	,	PUNCT
ecletica-1329	465	5	106	106	NUM
ecletica-1329	465	6	(	(	PUNCT
ecletica-1329	465	7	2	2	NUM
ecletica-1329	465	8	)	)	PUNCT
ecletica-1329	465	9	,	,	PUNCT
ecletica-1329	465	10	173–183	173–183	NUM
ecletica-1329	465	11	.	.	PUNCT
ecletica-1329	466	1	https://doi.org/10.1016/j.rmed.2011.10.015	https://doi.org/10.1016/j.rmed.2011.10.015	PROPN
ecletica-1329	466	2	swierczewska	swierczewska	PROPN
ecletica-1329	466	3	,	,	PUNCT
ecletica-1329	466	4	m.	m.	NOUN
ecletica-1329	466	5	;	;	PUNCT
ecletica-1329	466	6	lee	lee	PROPN
ecletica-1329	466	7	,	,	PUNCT
ecletica-1329	466	8	k.	k.	PROPN
ecletica-1329	466	9	c.	c.	PROPN
ecletica-1329	466	10	;	;	PUNCT
ecletica-1329	466	11	lee	lee	PROPN
ecletica-1329	466	12	,	,	PUNCT
ecletica-1329	466	13	s.	s.	PROPN
ecletica-1329	466	14	what	what	PRON
ecletica-1329	466	15	is	be	AUX
ecletica-1329	466	16	the	the	DET
ecletica-1329	466	17	future	future	NOUN
ecletica-1329	466	18	of	of	ADP
ecletica-1329	466	19	pegylated	pegylated	ADJ
ecletica-1329	466	20	therapies	therapy	NOUN
ecletica-1329	466	21	?	?	PUNCT
ecletica-1329	467	1	expert	expert	NOUN
ecletica-1329	467	2	opin	opin	NOUN
ecletica-1329	467	3	.	.	PUNCT
ecletica-1329	468	1	emerg	emerg	PROPN
ecletica-1329	468	2	.	.	PUNCT
ecletica-1329	469	1	drugs	drug	NOUN
ecletica-1329	469	2	2015	2015	NUM
ecletica-1329	469	3	,	,	PUNCT
ecletica-1329	469	4	20	20	NUM
ecletica-1329	469	5	(	(	PUNCT
ecletica-1329	469	6	4	4	NUM
ecletica-1329	469	7	)	)	PUNCT
ecletica-1329	469	8	,	,	PUNCT
ecletica-1329	469	9	531–536	531–536	NUM
ecletica-1329	469	10	.	.	PUNCT
ecletica-1329	470	1	https://doi.org/10.1517/14728214.2015.1113254	https://doi.org/10.1517/14728214.2015.1113254	PROPN
ecletica-1329	470	2	testa	testa	PROPN
ecletica-1329	470	3	,	,	PUNCT
ecletica-1329	470	4	b.	b.	PROPN
ecletica-1329	470	5	;	;	PUNCT
ecletica-1329	470	6	krämer	krämer	PROPN
ecletica-1329	470	7	,	,	PUNCT
ecletica-1329	470	8	s.	s.	PROPN
ecletica-1329	470	9	d.	d.	PROPN
ecletica-1329	470	10	the	the	DET
ecletica-1329	470	11	biochemistry	biochemistry	NOUN
ecletica-1329	470	12	of	of	ADP
ecletica-1329	470	13	drug	drug	NOUN
ecletica-1329	470	14	metabolism	metabolism	NOUN
ecletica-1329	470	15	–	–	PUNCT
ecletica-1329	470	16	an	an	DET
ecletica-1329	470	17	introduction	introduction	NOUN
ecletica-1329	470	18	:	:	PUNCT
ecletica-1329	470	19	part	part	NOUN
ecletica-1329	470	20	5	5	NUM
ecletica-1329	470	21	.	.	PUNCT
ecletica-1329	470	22	metabolism	metabolism	NOUN
ecletica-1329	470	23	and	and	CCONJ
ecletica-1329	470	24	bioactivity	bioactivity	NOUN
ecletica-1329	470	25	.	.	PUNCT
ecletica-1329	471	1	chem	chem	PROPN
ecletica-1329	471	2	.	.	PUNCT
ecletica-1329	472	1	biodivers	biodiver	NOUN
ecletica-1329	472	2	.	.	PUNCT
ecletica-1329	473	1	2009	2009	NUM
ecletica-1329	473	2	,	,	PUNCT
ecletica-1329	473	3	6	6	NUM
ecletica-1329	473	4	(	(	PUNCT
ecletica-1329	473	5	5	5	NUM
ecletica-1329	473	6	)	)	PUNCT
ecletica-1329	473	7	,	,	PUNCT
ecletica-1329	473	8	591–684	591–684	NUM
ecletica-1329	473	9	.	.	PUNCT
ecletica-1329	474	1	https://doi.org/10.1002/cbdv.200900022	https://doi.org/10.1002/cbdv.200900022	PROPN
ecletica-1329	474	2	trott	trott	PROPN
ecletica-1329	474	3	,	,	PUNCT
ecletica-1329	474	4	o.	o.	PROPN
ecletica-1329	474	5	;	;	PUNCT
ecletica-1329	474	6	olson	olson	NOUN
ecletica-1329	474	7	,	,	PUNCT
ecletica-1329	474	8	a.	a.	PROPN
ecletica-1329	474	9	j.	j.	PROPN
ecletica-1329	474	10	autodock	autodock	PROPN
ecletica-1329	474	11	vina	vina	PROPN
ecletica-1329	474	12	:	:	PUNCT
ecletica-1329	474	13	improving	improve	VERB
ecletica-1329	474	14	the	the	DET
ecletica-1329	474	15	speed	speed	NOUN
ecletica-1329	474	16	and	and	CCONJ
ecletica-1329	474	17	accuracy	accuracy	NOUN
ecletica-1329	474	18	of	of	ADP
ecletica-1329	474	19	docking	docking	NOUN
ecletica-1329	474	20	with	with	ADP
ecletica-1329	474	21	a	a	DET
ecletica-1329	474	22	new	new	ADJ
ecletica-1329	474	23	scoring	scoring	NOUN
ecletica-1329	474	24	function	function	NOUN
ecletica-1329	474	25	,	,	PUNCT
ecletica-1329	474	26	efficient	efficient	ADJ
ecletica-1329	474	27	optimization	optimization	NOUN
ecletica-1329	474	28	,	,	PUNCT
ecletica-1329	474	29	and	and	CCONJ
ecletica-1329	474	30	multithreading	multithreading	NOUN
ecletica-1329	474	31	.	.	PUNCT
ecletica-1329	475	1	j.	j.	PROPN
ecletica-1329	475	2	comput	comput	PROPN
ecletica-1329	475	3	.	.	PUNCT
ecletica-1329	476	1	chem	chem	PROPN
ecletica-1329	476	2	.	.	PUNCT
ecletica-1329	477	1	2010	2010	NUM
ecletica-1329	477	2	,	,	PUNCT
ecletica-1329	477	3	31	31	NUM
ecletica-1329	477	4	(	(	PUNCT
ecletica-1329	477	5	2	2	NUM
ecletica-1329	477	6	)	)	PUNCT
ecletica-1329	477	7	,	,	PUNCT
ecletica-1329	477	8	455–461	455–461	NUM
ecletica-1329	477	9	.	.	PUNCT
ecletica-1329	478	1	https://doi.org/10.1002/jcc.21334	https://doi.org/10.1002/jcc.21334	PROPN
ecletica-1329	478	2	vanommeslaeghe	vanommeslaeghe	NOUN
ecletica-1329	478	3	,	,	PUNCT
ecletica-1329	478	4	k.	k.	PROPN
ecletica-1329	478	5	;	;	PUNCT
ecletica-1329	478	6	guvench	guvench	NOUN
ecletica-1329	478	7	,	,	PUNCT
ecletica-1329	478	8	o.	o.	PROPN
ecletica-1329	478	9	;	;	PUNCT
ecletica-1329	478	10	mackerell	mackerell	PROPN
ecletica-1329	478	11	jr	jr	PROPN
ecletica-1329	478	12	,	,	PUNCT
ecletica-1329	478	13	a.	a.	PROPN
ecletica-1329	478	14	d.	d.	PROPN
ecletica-1329	478	15	molecular	molecular	PROPN
ecletica-1329	478	16	mechanics	mechanic	NOUN
ecletica-1329	478	17	.	.	PUNCT
ecletica-1329	479	1	curr	curr	PROPN
ecletica-1329	479	2	.	.	PUNCT
ecletica-1329	480	1	pharm	pharm	PROPN
ecletica-1329	480	2	.	.	PUNCT
ecletica-1329	481	1	des	des	PROPN
ecletica-1329	481	2	.	.	PROPN
ecletica-1329	481	3	2014	2014	NUM
ecletica-1329	481	4	,	,	PUNCT
ecletica-1329	481	5	20	20	NUM
ecletica-1329	481	6	(	(	PUNCT
ecletica-1329	481	7	20	20	NUM
ecletica-1329	481	8	)	)	PUNCT
ecletica-1329	481	9	,	,	PUNCT
ecletica-1329	481	10	3281–3292	3281–3292	NUM
ecletica-1329	481	11	.	.	PUNCT
ecletica-1329	482	1	https://doi.org/10.2174/13816128113199990600	https://doi.org/10.2174/13816128113199990600	VERB
ecletica-1329	482	2	veber	veber	PROPN
ecletica-1329	482	3	,	,	PUNCT
ecletica-1329	482	4	d.	d.	PROPN
ecletica-1329	482	5	f.	f.	PROPN
ecletica-1329	482	6	;	;	PUNCT
ecletica-1329	482	7	johnson	johnson	PROPN
ecletica-1329	482	8	,	,	PUNCT
ecletica-1329	482	9	s.	s.	PROPN
ecletica-1329	482	10	r.	r.	PROPN
ecletica-1329	482	11	;	;	PUNCT
ecletica-1329	482	12	cheng	cheng	PROPN
ecletica-1329	482	13	,	,	PUNCT
ecletica-1329	482	14	h.-y	h.-y	NOUN
ecletica-1329	482	15	.	.	PUNCT
ecletica-1329	482	16	;	;	PUNCT
ecletica-1329	482	17	smith	smith	PROPN
ecletica-1329	482	18	,	,	PUNCT
ecletica-1329	482	19	b.	b.	PROPN
ecletica-1329	482	20	r.	r.	PROPN
ecletica-1329	482	21	;	;	PUNCT
ecletica-1329	482	22	ward	ward	PROPN
ecletica-1329	482	23	,	,	PUNCT
ecletica-1329	482	24	k.	k.	PROPN
ecletica-1329	482	25	w.	w.	PROPN
ecletica-1329	482	26	;	;	PUNCT
ecletica-1329	482	27	kopple	kopple	PROPN
ecletica-1329	482	28	,	,	PUNCT
ecletica-1329	482	29	k.	k.	PROPN
ecletica-1329	482	30	d.	d.	PROPN
ecletica-1329	482	31	molecular	molecular	ADJ
ecletica-1329	482	32	properties	property	NOUN
ecletica-1329	482	33	that	that	PRON
ecletica-1329	482	34	influence	influence	VERB
ecletica-1329	482	35	the	the	DET
ecletica-1329	482	36	oral	oral	ADJ
ecletica-1329	482	37	bioavailability	bioavailability	NOUN
ecletica-1329	482	38	of	of	ADP
ecletica-1329	482	39	drug	drug	NOUN
ecletica-1329	482	40	candidates	candidate	NOUN
ecletica-1329	482	41	.	.	PUNCT
ecletica-1329	483	1	j.	j.	PROPN
ecletica-1329	483	2	med	med	PROPN
ecletica-1329	483	3	.	.	PROPN
ecletica-1329	483	4	chem	chem	PROPN
ecletica-1329	483	5	.	.	PUNCT
ecletica-1329	484	1	2002	2002	NUM
ecletica-1329	484	2	,	,	PUNCT
ecletica-1329	484	3	45	45	NUM
ecletica-1329	484	4	(	(	PUNCT
ecletica-1329	484	5	12	12	NUM
ecletica-1329	484	6	)	)	PUNCT
ecletica-1329	484	7	,	,	PUNCT
ecletica-1329	484	8	2615–2623	2615–2623	NUM
ecletica-1329	484	9	https://doi.org/10.1021/jm020017n	https://doi.org/10.1021/jm020017n	NOUN
ecletica-1329	484	10	veerasamy	veerasamy	NOUN
ecletica-1329	484	11	,	,	PUNCT
ecletica-1329	484	12	r.	r.	PROPN
ecletica-1329	484	13	;	;	PUNCT
ecletica-1329	484	14	rajak	rajak	ADV
ecletica-1329	484	15	,	,	PUNCT
ecletica-1329	484	16	h.	h.	PROPN
ecletica-1329	484	17	;	;	PUNCT
ecletica-1329	484	18	jain	jain	PROPN
ecletica-1329	484	19	,	,	PUNCT
ecletica-1329	484	20	a.	a.	PROPN
ecletica-1329	484	21	;	;	PUNCT
ecletica-1329	484	22	sivadasan	sivadasan	PROPN
ecletica-1329	484	23	,	,	PUNCT
ecletica-1329	484	24	s.	s.	PROPN
ecletica-1329	484	25	;	;	PUNCT
ecletica-1329	484	26	varghese	varghese	PROPN
ecletica-1329	484	27	,	,	PUNCT
ecletica-1329	484	28	c.	c.	PROPN
ecletica-1329	484	29	p.	p.	PROPN
ecletica-1329	484	30	;	;	PUNCT
ecletica-1329	484	31	agrawal	agrawal	PROPN
ecletica-1329	484	32	,	,	PUNCT
ecletica-1329	484	33	r.	r.	PROPN
ecletica-1329	484	34	k.	k.	PROPN
ecletica-1329	484	35	validation	validation	PROPN
ecletica-1329	484	36	of	of	ADP
ecletica-1329	484	37	qsar	qsar	NOUN
ecletica-1329	484	38	models	model	NOUN
ecletica-1329	484	39	strategies	strategy	NOUN
ecletica-1329	484	40	and	and	CCONJ
ecletica-1329	484	41	importance	importance	NOUN
ecletica-1329	484	42	.	.	PUNCT
ecletica-1329	485	1	int	int	NOUN
ecletica-1329	485	2	.	.	PUNCT
ecletica-1329	486	1	j.	j.	PROPN
ecletica-1329	486	2	drug	drug	PROPN
ecletica-1329	486	3	discov	discov	PROPN
ecletica-1329	486	4	.	.	PUNCT
ecletica-1329	487	1	2011	2011	NUM
ecletica-1329	487	2	,	,	PUNCT
ecletica-1329	487	3	2	2	NUM
ecletica-1329	487	4	(	(	PUNCT
ecletica-1329	487	5	3	3	NUM
ecletica-1329	487	6	)	)	PUNCT
ecletica-1329	487	7	,	,	PUNCT
ecletica-1329	488	1	511–519	511–519	NUM
ecletica-1329	488	2	.	.	PUNCT
ecletica-1329	489	1	wang	wang	PROPN
ecletica-1329	489	2	,	,	PUNCT
ecletica-1329	489	3	h.	h.	PROPN
ecletica-1329	489	4	;	;	PUNCT
ecletica-1329	489	5	liu	liu	PROPN
ecletica-1329	489	6	,	,	PUNCT
ecletica-1329	489	7	x.	x.	PROPN
ecletica-1329	489	8	;	;	PUNCT
ecletica-1329	489	9	rice	rice	PROPN
ecletica-1329	489	10	,	,	PUNCT
ecletica-1329	489	11	s.	s.	PROPN
ecletica-1329	489	12	j.	j.	PROPN
ecletica-1329	489	13	;	;	PUNCT
ecletica-1329	489	14	belani	belani	NOUN
ecletica-1329	489	15	,	,	PUNCT
ecletica-1329	489	16	c.	c.	PROPN
ecletica-1329	489	17	p.	p.	NOUN
ecletica-1329	489	18	pulmonary	pulmonary	ADJ
ecletica-1329	489	19	rehabilitation	rehabilitation	NOUN
ecletica-1329	489	20	in	in	ADP
ecletica-1329	489	21	lung	lung	NOUN
ecletica-1329	489	22	cancer	cancer	NOUN
ecletica-1329	489	23	.	.	PUNCT
ecletica-1329	490	1	pm&r	pm&r	PROPN
ecletica-1329	490	2	2016	2016	NUM
ecletica-1329	490	3	,	,	PUNCT
ecletica-1329	490	4	8	8	NUM
ecletica-1329	490	5	(	(	PUNCT
ecletica-1329	490	6	10	10	NUM
ecletica-1329	490	7	)	)	PUNCT
ecletica-1329	490	8	,	,	PUNCT
ecletica-1329	490	9	990–996	990–996	NUM
ecletica-1329	490	10	.	.	PUNCT
ecletica-1329	491	1	https://doi.org/10.1016/j.pmrj.2016.03.010	https://doi.org/10.1016/j.pmrj.2016.03.010	PROPN
ecletica-1329	491	2	waziri	waziri	PROPN
ecletica-1329	491	3	,	,	PUNCT
ecletica-1329	491	4	i.	i.	PROPN
ecletica-1329	491	5	;	;	PUNCT
ecletica-1329	491	6	kelani	kelani	PROPN
ecletica-1329	491	7	,	,	PUNCT
ecletica-1329	491	8	m.	m.	NOUN
ecletica-1329	491	9	t.	t.	PROPN
ecletica-1329	491	10	;	;	PUNCT
ecletica-1329	491	11	oyedeji	oyedeji	PROPN
ecletica-1329	491	12	-	-	PUNCT
ecletica-1329	491	13	amusa	amusa	PROPN
ecletica-1329	491	14	,	,	PUNCT
ecletica-1329	491	15	m.	m.	NOUN
ecletica-1329	491	16	o.	o.	PROPN
ecletica-1329	491	17	;	;	PUNCT
ecletica-1329	491	18	oyebamiji	oyebamiji	PROPN
ecletica-1329	491	19	,	,	PUNCT
ecletica-1329	491	20	a.	a.	PROPN
ecletica-1329	491	21	k.	k.	PROPN
ecletica-1329	491	22	;	;	PUNCT
ecletica-1329	491	23	coetzee	coetzee	PROPN
ecletica-1329	491	24	,	,	PUNCT
ecletica-1329	491	25	l.-c	l.-c	PROPN
ecletica-1329	491	26	.	.	PUNCT
ecletica-1329	492	1	c.	c.	PROPN
ecletica-1329	492	2	;	;	PUNCT
ecletica-1329	492	3	adeyinka	adeyinka	PROPN
ecletica-1329	492	4	,	,	PUNCT
ecletica-1329	492	5	a.	a.	PROPN
ecletica-1329	492	6	s.	s.	PROPN
ecletica-1329	492	7	;	;	PUNCT
ecletica-1329	492	8	muller	muller	NOUN
ecletica-1329	492	9	,	,	PUNCT
ecletica-1329	492	10	a.	a.	PROPN
ecletica-1329	492	11	j.	j.	PROPN
ecletica-1329	492	12	synthesis	synthesis	PROPN
ecletica-1329	492	13	and	and	CCONJ
ecletica-1329	492	14	computational	computational	ADJ
ecletica-1329	492	15	investigation	investigation	NOUN
ecletica-1329	492	16	of	of	ADP
ecletica-1329	492	17	n	n	CCONJ
ecletica-1329	492	18	,	,	PUNCT
ecletica-1329	492	19	n	n	PRON
ecletica-1329	492	20	-dimethyl4-[(z)-(phenylimino)methyl]aniline	-dimethyl4-[(z)-(phenylimino)methyl]aniline	NOUN
ecletica-1329	492	21	derivatives	derivative	NOUN
ecletica-1329	492	22	:	:	PUNCT
ecletica-1329	492	23	biological	biological	ADJ
ecletica-1329	492	24	and	and	CCONJ
ecletica-1329	492	25	quantitative	quantitative	ADJ
ecletica-1329	492	26	structural	structural	ADJ
ecletica-1329	492	27	activity	activity	NOUN
ecletica-1329	492	28	relationship	relationship	NOUN
ecletica-1329	492	29	studies	study	NOUN
ecletica-1329	492	30	.	.	PUNCT
ecletica-1329	493	1	j.	j.	PROPN
ecletica-1329	493	2	mol	mol	PROPN
ecletica-1329	493	3	.	.	PROPN
ecletica-1329	493	4	struct	struct	NOUN
ecletica-1329	493	5	.	.	PUNCT
ecletica-1329	494	1	2023	2023	NUM
ecletica-1329	494	2	,	,	PUNCT
ecletica-1329	494	3	1276	1276	NUM
ecletica-1329	494	4	,	,	PUNCT
ecletica-1329	494	5	134756	134756	NUM
ecletica-1329	494	6	.	.	PUNCT
ecletica-1329	495	1	https://doi.org/10.1016/j.molstruc.2022.134756	https://doi.org/10.1016/j.molstruc.2022.134756	PROPN
ecletica-1329	495	2	yang	yang	PROPN
ecletica-1329	495	3	,	,	PUNCT
ecletica-1329	495	4	l.	l.	PROPN
ecletica-1329	495	5	;	;	PUNCT
ecletica-1329	495	6	feng	feng	PROPN
ecletica-1329	495	7	,	,	PUNCT
ecletica-1329	495	8	j.-k	j.-k	PROPN
ecletica-1329	495	9	.	.	PUNCT
ecletica-1329	495	10	;	;	PUNCT
ecletica-1329	496	1	ren	ren	PROPN
ecletica-1329	496	2	,	,	PUNCT
ecletica-1329	496	3	a.-m	a.-m	PROPN
ecletica-1329	496	4	.	.	PUNCT
ecletica-1329	497	1	theoretical	theoretical	ADJ
ecletica-1329	497	2	studies	study	NOUN
ecletica-1329	497	3	on	on	ADP
ecletica-1329	497	4	the	the	DET
ecletica-1329	497	5	electronic	electronic	ADJ
ecletica-1329	497	6	and	and	CCONJ
ecletica-1329	497	7	optical	optical	ADJ
ecletica-1329	497	8	properties	property	NOUN
ecletica-1329	497	9	of	of	ADP
ecletica-1329	497	10	two	two	NUM
ecletica-1329	497	11	thiophene	thiophene	NOUN
ecletica-1329	497	12	–	–	PUNCT
ecletica-1329	497	13	fluorene	fluorene	NOUN
ecletica-1329	497	14	based	base	VERB
ecletica-1329	497	15	π	π	PROPN
ecletica-1329	497	16	-	-	PUNCT
ecletica-1329	497	17	conjugated	conjugate	VERB
ecletica-1329	497	18	copolymers	copolymer	NOUN
ecletica-1329	497	19	.	.	PUNCT
ecletica-1329	498	1	polymer	polymer	NOUN
ecletica-1329	498	2	2005	2005	NUM
ecletica-1329	498	3	,	,	PUNCT
ecletica-1329	498	4	46	46	NUM
ecletica-1329	498	5	(	(	PUNCT
ecletica-1329	498	6	24	24	NUM
ecletica-1329	498	7	)	)	PUNCT
ecletica-1329	498	8	,	,	PUNCT
ecletica-1329	498	9	10970–10981	10970–10981	NUM
ecletica-1329	498	10	.	.	PUNCT
ecletica-1329	499	1	https://doi.org/10.1016/j.polymer.2005.09.050	https://doi.org/10.1016/j.polymer.2005.09.050	PROPN
ecletica-1329	499	2	yasuda	yasuda	PROPN
ecletica-1329	499	3	,	,	PUNCT
ecletica-1329	499	4	h.	h.	PROPN
ecletica-1329	499	5	;	;	PUNCT
ecletica-1329	499	6	park	park	PROPN
ecletica-1329	499	7	,	,	PUNCT
ecletica-1329	499	8	e.	e.	PROPN
ecletica-1329	499	9	;	;	PUNCT
ecletica-1329	499	10	yun	yun	PROPN
ecletica-1329	499	11	,	,	PUNCT
ecletica-1329	499	12	c.	c.	PROPN
ecletica-1329	499	13	h.	h.	PROPN
ecletica-1329	499	14	;	;	PUNCT
ecletica-1329	499	15	sng	sng	NOUN
ecletica-1329	499	16	,	,	PUNCT
ecletica-1329	499	17	n.	n.	PROPN
ecletica-1329	499	18	j.	j.	PROPN
ecletica-1329	499	19	;	;	PUNCT
ecletica-1329	499	20	lucena	lucena	PROPN
ecletica-1329	499	21	-	-	PUNCT
ecletica-1329	499	22	araujo	araujo	NOUN
ecletica-1329	499	23	,	,	PUNCT
ecletica-1329	499	24	a.	a.	PROPN
ecletica-1329	499	25	r.	r.	PROPN
ecletica-1329	499	26	;	;	PUNCT
ecletica-1329	499	27	yeo	yeo	PROPN
ecletica-1329	499	28	,	,	PUNCT
ecletica-1329	499	29	w.	w.	PROPN
ecletica-1329	499	30	l.	l.	PROPN
ecletica-1329	499	31	;	;	PUNCT
ecletica-1329	499	32	huberman	huberman	NOUN
ecletica-1329	499	33	,	,	PUNCT
ecletica-1329	499	34	m.	m.	NOUN
ecletica-1329	499	35	s.	s.	PROPN
ecletica-1329	499	36	;	;	PUNCT
ecletica-1329	499	37	cohen	cohen	PROPN
ecletica-1329	499	38	,	,	PUNCT
ecletica-1329	499	39	d.	d.	PROPN
ecletica-1329	499	40	w.	w.	PROPN
ecletica-1329	499	41	;	;	PUNCT
ecletica-1329	499	42	nakayama	nakayama	PROPN
ecletica-1329	499	43	,	,	PUNCT
ecletica-1329	499	44	s.	s.	PROPN
ecletica-1329	499	45	;	;	PUNCT
ecletica-1329	499	46	ishioka	ishioka	NOUN
ecletica-1329	499	47	,	,	PUNCT
ecletica-1329	499	48	k.	k.	PROPN
ecletica-1329	499	49	;	;	PUNCT
ecletica-1329	499	50	yamaguchi	yamaguchi	PROPN
ecletica-1329	499	51	,	,	PUNCT
ecletica-1329	499	52	n.	n.	PROPN
ecletica-1329	499	53	;	;	PUNCT
ecletica-1329	499	54	hanna	hanna	PROPN
ecletica-1329	499	55	,	,	PUNCT
ecletica-1329	499	56	m.	m.	NOUN
ecletica-1329	499	57	;	;	PUNCT
ecletica-1329	499	58	https://revista.iq.unesp.br/index.php/ecletica	https://revista.iq.unesp.br/index.php/ecletica	PROPN
ecletica-1329	499	59	https://doi.org/10.26850/1678-4618eqj.v48.1.2023.p55-71	https://doi.org/10.26850/1678-4618eqj.v48.1.2023.p55-71	PROPN
ecletica-1329	499	60	https://doi.org/10.1007/s42250-021-00276-2	https://doi.org/10.1007/s42250-021-00276-2	X
ecletica-1329	499	61	https://doi.org/10.1007/s42250-021-00276-2	https://doi.org/10.1007/s42250-021-00276-2	X
ecletica-1329	499	62	https://doi.org/10.1007/s42250-021-00276-2	https://doi.org/10.1007/s42250-021-00276-2	X
ecletica-1329	499	63	https://doi.org/10.1007/s42250-021-00276-2	https://doi.org/10.1007/s42250-021-00276-2	NOUN
ecletica-1329	499	64	https://doi.org/10.1007/s42250-021-00276-2	https://doi.org/10.1007/s42250-021-00276-2	NUM
ecletica-1329	499	65	https://doi.org/10.25135/acg.oc.132.2203	https://doi.org/10.25135/acg.oc.132.2203	X
ecletica-1329	499	66	https://doi.org/10.25135/acg.oc.132.2203	https://doi.org/10.25135/acg.oc.132.2203	X
ecletica-1329	499	67	https://doi.org/10.25135/acg.oc.132.2203	https://doi.org/10.25135/acg.oc.132.2203	X
ecletica-1329	499	68	https://doi.org/10.25135/acg.oc.132.2203	https://doi.org/10.25135/acg.oc.132.2203	X
ecletica-1329	499	69	https://doi.org/10.25135/acg.oc.132.2203	https://doi.org/10.25135/acg.oc.132.2203	X
ecletica-1329	499	70	https://doi.org/10.25135/acg.oc.132.2203	https://doi.org/10.25135/acg.oc.132.2203	PROPN
ecletica-1329	499	71	20https:/doi.org/10.1021	20https:/doi.org/10.1021	NUM
ecletica-1329	499	72	/	/	SYM
ecletica-1329	500	1	ja983494x	ja983494x	PRON
ecletica-1329	500	2	20https:/doi.org/10.1021	20https:/doi.org/10.1021	NUM
ecletica-1329	500	3	/	/	SYM
ecletica-1329	500	4	ja983494x	ja983494x	PRON
ecletica-1329	500	5	20https:/doi.org/10.1021	20https:/doi.org/10.1021	NUM
ecletica-1329	500	6	/	/	SYM
ecletica-1329	500	7	ja983494x	ja983494x	PRON
ecletica-1329	500	8	https://doi.org/10.1002/jcc.20084	https://doi.org/10.1002/jcc.20084	NOUN
ecletica-1329	500	9	https://doi.org/10.1002/jcc.20084	https://doi.org/10.1002/jcc.20084	PROPN
ecletica-1329	500	10	https://doi.org/10.1002/jcc.20084	https://doi.org/10.1002/jcc.20084	PROPN
ecletica-1329	500	11	https://doi.org/10.1002/jcc.20084	https://doi.org/10.1002/jcc.20084	PROPN
ecletica-1329	501	1	https://doi.org/10.1002/jcc.20084	https://doi.org/10.1002/jcc.20084	NOUN
ecletica-1329	501	2	https://doi.org/10.1007/978-1-4020-9783-6	https://doi.org/10.1007/978-1-4020-9783-6	PROPN
ecletica-1329	502	1	https://doi.org/10.1007/978-1-4020-9783-6	https://doi.org/10.1007/978-1-4020-9783-6	PROPN
ecletica-1329	502	2	https://doi.org/10.1007/978-1-4020-9783-6	https://doi.org/10.1007/978-1-4020-9783-6	PROPN
ecletica-1329	502	3	https://doi.org/10.1007/s11095-008-9787-9	https://doi.org/10.1007/s11095-008-9787-9	PROPN
ecletica-1329	502	4	https://doi.org/10.1007/s11095-008-9787-9	https://doi.org/10.1007/s11095-008-9787-9	PROPN
ecletica-1329	502	5	https://doi.org/10.1007/s11095-008-9787-9	https://doi.org/10.1007/s11095-008-9787-9	PROPN
ecletica-1329	503	1	https://doi.org/10.1007/s11095-008-9787-9	https://doi.org/10.1007/s11095-008-9787-9	PROPN
ecletica-1329	504	1	https://doi.org/10.1007/s11095-008-9787-9	https://doi.org/10.1007/s11095-008-9787-9	VERB
ecletica-1329	504	2	https://doi.org/10.1016/j.bmc.2012.04.042	https://doi.org/10.1016/j.bmc.2012.04.042	NOUN
ecletica-1329	504	3	https://doi.org/10.1016/j.bmc.2012.04.042	https://doi.org/10.1016/j.bmc.2012.04.042	NOUN
ecletica-1329	504	4	https://doi.org/10.1016/j.bmc.2012.04.042	https://doi.org/10.1016/j.bmc.2012.04.042	NOUN
ecletica-1329	504	5	https://doi.org/10.1016/j.bmc.2012.04.042	https://doi.org/10.1016/j.bmc.2012.04.042	NOUN
ecletica-1329	504	6	https://doi.org/10.1016/j.bmc.2012.04.042	https://doi.org/10.1016/j.bmc.2012.04.042	ADP
ecletica-1329	504	7	https://doi.org/10.1016/j.bmc.2012.04.042	https://doi.org/10.1016/j.bmc.2012.04.042	ADP
ecletica-1329	504	8	https://doi.org/10.1016/j.bmc.2012.04.042	https://doi.org/10.1016/j.bmc.2012.04.042	NOUN
ecletica-1329	504	9	https://doi.org/10.1016/j.bmc.2012.04.042	https://doi.org/10.1016/j.bmc.2012.04.042	PROPN
ecletica-1329	504	10	https://doi.org/10.3322/caac.21332	https://doi.org/10.3322/caac.21332	X
ecletica-1329	504	11	https://doi.org/10.3322/caac.21332	https://doi.org/10.3322/caac.21332	AUX
ecletica-1329	504	12	https://doi.org/10.3322/caac.21332	https://doi.org/10.3322/caac.21332	NOUN
ecletica-1329	505	1	https://doi.org/10.1016/j.rmed.2011.10.015	https://doi.org/10.1016/j.rmed.2011.10.015	PROPN
ecletica-1329	505	2	https://doi.org/10.1016/j.rmed.2011.10.015	https://doi.org/10.1016/j.rmed.2011.10.015	PROPN
ecletica-1329	505	3	https://doi.org/10.1016/j.rmed.2011.10.015	https://doi.org/10.1016/j.rmed.2011.10.015	PROPN
ecletica-1329	505	4	https://doi.org/10.1016/j.rmed.2011.10.015	https://doi.org/10.1016/j.rmed.2011.10.015	PROPN
ecletica-1329	505	5	https://doi.org/10.1016/j.rmed.2011.10.015	https://doi.org/10.1016/j.rmed.2011.10.015	PROPN
ecletica-1329	505	6	https://doi.org/10.1517/14728214.2015.1113254	https://doi.org/10.1517/14728214.2015.1113254	PUNCT
ecletica-1329	505	7	https://doi.org/10.1517/14728214.2015.1113254	https://doi.org/10.1517/14728214.2015.1113254	X
ecletica-1329	506	1	https://doi.org/10.1517/14728214.2015.1113254	https://doi.org/10.1517/14728214.2015.1113254	X
ecletica-1329	507	1	https://doi.org/10.1517/14728214.2015.1113254	https://doi.org/10.1517/14728214.2015.1113254	PROPN
ecletica-1329	507	2	https://doi.org/10.1002/cbdv.200900022	https://doi.org/10.1002/cbdv.200900022	NOUN
ecletica-1329	507	3	https://doi.org/10.1002/cbdv.200900022	https://doi.org/10.1002/cbdv.200900022	NOUN
ecletica-1329	507	4	https://doi.org/10.1002/cbdv.200900022	https://doi.org/10.1002/cbdv.200900022	NOUN
ecletica-1329	507	5	https://doi.org/10.1002/cbdv.200900022	https://doi.org/10.1002/cbdv.200900022	NOUN
ecletica-1329	508	1	https://doi.org/10.1002/jcc.21334	https://doi.org/10.1002/jcc.21334	PROPN
ecletica-1329	508	2	https://doi.org/10.1002/jcc.21334	https://doi.org/10.1002/jcc.21334	PROPN
ecletica-1329	508	3	https://doi.org/10.1002/jcc.21334	https://doi.org/10.1002/jcc.21334	PROPN
ecletica-1329	508	4	https://doi.org/10.1002/jcc.21334	https://doi.org/10.1002/jcc.21334	PROPN
ecletica-1329	508	5	https://doi.org/10.2174/13816128113199990600	https://doi.org/10.2174/13816128113199990600	VERB
ecletica-1329	508	6	https://doi.org/10.2174/13816128113199990600	https://doi.org/10.2174/13816128113199990600	PROPN
ecletica-1329	508	7	https://doi.org/10.2174/13816128113199990600	https://doi.org/10.2174/13816128113199990600	NOUN
ecletica-1329	508	8	https://doi.org/10.1021/jm020017n	https://doi.org/10.1021/jm020017n	NOUN
ecletica-1329	508	9	https://doi.org/10.1021/jm020017n	https://doi.org/10.1021/jm020017n	NOUN
ecletica-1329	508	10	https://doi.org/10.1021/jm020017n	https://doi.org/10.1021/jm020017n	NOUN
ecletica-1329	508	11	https://doi.org/10.1021/jm020017n	https://doi.org/10.1021/jm020017n	NOUN
ecletica-1329	508	12	https://doi.org/10.1021/jm020017n	https://doi.org/10.1021/jm020017n	NOUN
ecletica-1329	508	13	https://doi.org/10.1016/j.pmrj.2016.03.010	https://doi.org/10.1016/j.pmrj.2016.03.010	NOUN
ecletica-1329	508	14	https://doi.org/10.1016/j.pmrj.2016.03.010	https://doi.org/10.1016/j.pmrj.2016.03.010	NOUN
ecletica-1329	508	15	https://doi.org/10.1016/j.pmrj.2016.03.010	https://doi.org/10.1016/j.pmrj.2016.03.010	NOUN
ecletica-1329	508	16	https://doi.org/10.1016/j.molstruc.2022.134756	https://doi.org/10.1016/j.molstruc.2022.134756	PROPN
ecletica-1329	508	17	https://doi.org/10.1016/j.molstruc.2022.134756	https://doi.org/10.1016/j.molstruc.2022.134756	PROPN
ecletica-1329	508	18	https://doi.org/10.1016/j.molstruc.2022.134756	https://doi.org/10.1016/j.molstruc.2022.134756	PROPN
ecletica-1329	508	19	https://doi.org/10.1016/j.molstruc.2022.134756	https://doi.org/10.1016/j.molstruc.2022.134756	PROPN
ecletica-1329	508	20	https://doi.org/10.1016/j.molstruc.2022.134756	https://doi.org/10.1016/j.molstruc.2022.134756	PROPN
ecletica-1329	508	21	https://doi.org/10.1016/j.molstruc.2022.134756	https://doi.org/10.1016/j.molstruc.2022.134756	PROPN
ecletica-1329	508	22	https://doi.org/10.1016/j.molstruc.2022.134756	https://doi.org/10.1016/j.molstruc.2022.134756	VERB
ecletica-1329	508	23	https://doi.org/10.1016/j.polymer.2005.09.050	https://doi.org/10.1016/j.polymer.2005.09.050	PROPN
ecletica-1329	508	24	https://doi.org/10.1016/j.polymer.2005.09.050	https://doi.org/10.1016/j.polymer.2005.09.050	PROPN
ecletica-1329	508	25	https://doi.org/10.1016/j.polymer.2005.09.050	https://doi.org/10.1016/j.polymer.2005.09.050	PROPN
ecletica-1329	508	26	https://doi.org/10.1016/j.polymer.2005.09.050	https://doi.org/10.1016/j.polymer.2005.09.050	PROPN
ecletica-1329	508	27	https://doi.org/10.1126/scitranslmed.3007205	https://doi.org/10.1126/scitranslmed.3007205	NOUN
ecletica-1329	508	28	https://doi.org/10.1126/scitranslmed.3007205	https://doi.org/10.1126/scitranslmed.3007205	PROPN
ecletica-1329	508	29	https://doi.org/10.1126/scitranslmed.3007205	https://doi.org/10.1126/scitranslmed.3007205	PROPN
ecletica-1329	508	30	original	original	ADJ
ecletica-1329	508	31	article	article	NOUN
ecletica-1329	508	32	revista.iq.unesp.br	revista.iq.unesp.br	PROPN
ecletica-1329	508	33	71	71	NUM
ecletica-1329	508	34	eclética	eclética	PROPN
ecletica-1329	508	35	química	química	PROPN
ecletica-1329	508	36	,	,	PUNCT
ecletica-1329	508	37	vol	vol	NOUN
ecletica-1329	508	38	.	.	PROPN
ecletica-1329	508	39	48	48	NUM
ecletica-1329	508	40	,	,	PUNCT
ecletica-1329	508	41	n.	n.	NOUN
ecletica-1329	508	42	1	1	NUM
ecletica-1329	508	43	,	,	PUNCT
ecletica-1329	508	44	2023	2023	NUM
ecletica-1329	508	45	,	,	PUNCT
ecletica-1329	508	46	55	55	NUM
ecletica-1329	508	47	-	-	SYM
ecletica-1329	508	48	71	71	NUM
ecletica-1329	508	49	issn	issn	NOUN
ecletica-1329	508	50	:	:	PUNCT
ecletica-1329	508	51	1678	1678	NUM
ecletica-1329	508	52	-	-	SYM
ecletica-1329	508	53	4618	4618	NUM
ecletica-1329	508	54	doi	doi	NOUN
ecletica-1329	508	55	:	:	PUNCT
ecletica-1329	508	56	10.26850/1678	10.26850/1678	NUM
ecletica-1329	508	57	-	-	PUNCT
ecletica-1329	508	58	4618eqj.v48.1.2023.p55	4618eqj.v48.1.2023.p55	NUM
ecletica-1329	508	59	-	-	PUNCT
ecletica-1329	508	60	71	71	NUM
ecletica-1329	508	61	oxnard	oxnard	NOUN
ecletica-1329	508	62	,	,	PUNCT
ecletica-1329	508	63	g.	g.	PROPN
ecletica-1329	508	64	r.	r.	PROPN
ecletica-1329	508	65	;	;	PUNCT
ecletica-1329	508	66	lathan	lathan	PROPN
ecletica-1329	508	67	,	,	PUNCT
ecletica-1329	508	68	c.	c.	PROPN
ecletica-1329	508	69	s.	s.	PROPN
ecletica-1329	508	70	;	;	PUNCT
ecletica-1329	508	71	moran	moran	PROPN
ecletica-1329	508	72	,	,	PUNCT
ecletica-1329	508	73	t.	t.	PROPN
ecletica-1329	508	74	;	;	PUNCT
ecletica-1329	508	75	sequist	sequist	PROPN
ecletica-1329	508	76	,	,	PUNCT
ecletica-1329	508	77	l.	l.	PROPN
ecletica-1329	509	1	v.	v.	PROPN
ecletica-1329	509	2	;	;	PUNCT
ecletica-1329	509	3	chaft	chaft	PROPN
ecletica-1329	509	4	,	,	PUNCT
ecletica-1329	509	5	j.	j.	PROPN
ecletica-1329	509	6	e.	e.	PROPN
ecletica-1329	509	7	;	;	PUNCT
ecletica-1329	509	8	riely	riely	PROPN
ecletica-1329	509	9	,	,	PUNCT
ecletica-1329	509	10	g.	g.	PROPN
ecletica-1329	509	11	j.	j.	PROPN
ecletica-1329	509	12	;	;	PUNCT
ecletica-1329	509	13	arcila	arcila	PROPN
ecletica-1329	509	14	,	,	PUNCT
ecletica-1329	509	15	m.	m.	PROPN
ecletica-1329	509	16	e.	e.	PROPN
ecletica-1329	509	17	;	;	PUNCT
ecletica-1329	509	18	soo	soo	PROPN
ecletica-1329	509	19	,	,	PUNCT
ecletica-1329	509	20	r.	r.	PROPN
ecletica-1329	509	21	a.	a.	PROPN
ecletica-1329	509	22	;	;	PUNCT
ecletica-1329	509	23	meyerson	meyerson	NOUN
ecletica-1329	509	24	,	,	PUNCT
ecletica-1329	509	25	m.	m.	NOUN
ecletica-1329	509	26	;	;	PUNCT
ecletica-1329	509	27	eck	eck	PROPN
ecletica-1329	509	28	,	,	PUNCT
ecletica-1329	509	29	m.	m.	NOUN
ecletica-1329	509	30	j.	j.	PROPN
ecletica-1329	509	31	;	;	PUNCT
ecletica-1329	509	32	kobayashi	kobayashi	PROPN
ecletica-1329	509	33	,	,	PUNCT
ecletica-1329	509	34	s.	s.	PROPN
ecletica-1329	509	35	s.	s.	PROPN
ecletica-1329	509	36	;	;	PUNCT
ecletica-1329	509	37	costa	costa	PROPN
ecletica-1329	509	38	,	,	PUNCT
ecletica-1329	509	39	d.	d.	PROPN
ecletica-1329	509	40	b.	b.	PROPN
ecletica-1329	509	41	structural	structural	ADJ
ecletica-1329	509	42	,	,	PUNCT
ecletica-1329	509	43	biochemical	biochemical	ADJ
ecletica-1329	509	44	,	,	PUNCT
ecletica-1329	509	45	and	and	CCONJ
ecletica-1329	509	46	clinical	clinical	ADJ
ecletica-1329	509	47	characterization	characterization	NOUN
ecletica-1329	509	48	of	of	ADP
ecletica-1329	509	49	epidermal	epidermal	ADJ
ecletica-1329	509	50	growth	growth	NOUN
ecletica-1329	509	51	factor	factor	NOUN
ecletica-1329	509	52	receptor	receptor	NOUN
ecletica-1329	509	53	(	(	PUNCT
ecletica-1329	509	54	egfr	egfr	X
ecletica-1329	509	55	)	)	PUNCT
ecletica-1329	509	56	exon	exon	NOUN
ecletica-1329	509	57	20	20	NUM
ecletica-1329	509	58	insertion	insertion	NOUN
ecletica-1329	509	59	mutations	mutation	NOUN
ecletica-1329	509	60	in	in	ADP
ecletica-1329	509	61	lung	lung	NOUN
ecletica-1329	509	62	cancer	cancer	NOUN
ecletica-1329	509	63	.	.	PUNCT
ecletica-1329	510	1	sci	sci	PROPN
ecletica-1329	510	2	.	.	PROPN
ecletica-1329	510	3	transl	transl	PROPN
ecletica-1329	510	4	.	.	PUNCT
ecletica-1329	511	1	med	med	PROPN
ecletica-1329	511	2	.	.	PUNCT
ecletica-1329	512	1	2013	2013	NUM
ecletica-1329	512	2	,	,	PUNCT
ecletica-1329	512	3	5	5	NUM
ecletica-1329	512	4	(	(	PUNCT
ecletica-1329	512	5	216	216	NUM
ecletica-1329	512	6	)	)	PUNCT
ecletica-1329	512	7	,	,	PUNCT
ecletica-1329	512	8	216ra177	216ra177	NUM
ecletica-1329	512	9	.	.	PUNCT
ecletica-1329	512	10	https://doi.org/10.1126/scitranslmed.3007205	https://doi.org/10.1126/scitranslmed.3007205	PROPN
ecletica-1329	512	11	zhang	zhang	PROPN
ecletica-1329	512	12	,	,	PUNCT
ecletica-1329	512	13	z.	z.	PROPN
ecletica-1329	512	14	;	;	PUNCT
ecletica-1329	512	15	lee	lee	PROPN
ecletica-1329	512	16	,	,	PUNCT
ecletica-1329	512	17	j.	j.	PROPN
ecletica-1329	512	18	c.	c.	PROPN
ecletica-1329	512	19	;	;	PUNCT
ecletica-1329	512	20	lin	lin	PROPN
ecletica-1329	512	21	,	,	PUNCT
ecletica-1329	512	22	l.	l.	PROPN
ecletica-1329	512	23	;	;	PUNCT
ecletica-1329	512	24	olivas	olivas	PROPN
ecletica-1329	512	25	,	,	PUNCT
ecletica-1329	512	26	v.	v.	ADV
ecletica-1329	512	27	;	;	PUNCT
ecletica-1329	512	28	au	au	X
ecletica-1329	512	29	,	,	PUNCT
ecletica-1329	512	30	v.	v.	ADV
ecletica-1329	512	31	;	;	PUNCT
ecletica-1329	512	32	laframboise	laframboise	NOUN
ecletica-1329	512	33	,	,	PUNCT
ecletica-1329	512	34	t.	t.	PROPN
ecletica-1329	512	35	;	;	PUNCT
ecletica-1329	512	36	abdel	abdel	PROPN
ecletica-1329	512	37	-	-	PUNCT
ecletica-1329	512	38	rahman	rahman	PROPN
ecletica-1329	512	39	,	,	PUNCT
ecletica-1329	512	40	m.	m.	NOUN
ecletica-1329	512	41	;	;	PUNCT
ecletica-1329	512	42	wang	wang	PROPN
ecletica-1329	512	43	,	,	PUNCT
ecletica-1329	512	44	x.	x.	PROPN
ecletica-1329	512	45	;	;	PUNCT
ecletica-1329	512	46	levine	levine	PROPN
ecletica-1329	512	47	,	,	PUNCT
ecletica-1329	512	48	a.	a.	PROPN
ecletica-1329	512	49	d.	d.	PROPN
ecletica-1329	512	50	;	;	PUNCT
ecletica-1329	512	51	rho	rho	PROPN
ecletica-1329	512	52	,	,	PUNCT
ecletica-1329	512	53	j.	j.	PROPN
ecletica-1329	512	54	k.	k.	PROPN
ecletica-1329	512	55	;	;	PUNCT
ecletica-1329	512	56	choi	choi	PROPN
ecletica-1329	512	57	,	,	PUNCT
ecletica-1329	512	58	y.	y.	PROPN
ecletica-1329	512	59	j.	j.	PROPN
ecletica-1329	512	60	;	;	PUNCT
ecletica-1329	512	61	choi	choi	NOUN
ecletica-1329	512	62	,	,	PUNCT
ecletica-1329	512	63	c.	c.	NOUN
ecletica-1329	512	64	m.	m.	NOUN
ecletica-1329	512	65	;	;	PUNCT
ecletica-1329	512	66	kim	kim	PROPN
ecletica-1329	512	67	,	,	PUNCT
ecletica-1329	512	68	s.	s.	PROPN
ecletica-1329	512	69	w.	w.	PROPN
ecletica-1329	512	70	;	;	PUNCT
ecletica-1329	512	71	jang	jang	PROPN
ecletica-1329	512	72	,	,	PUNCT
ecletica-1329	512	73	s.	s.	PROPN
ecletica-1329	512	74	j.	j.	PROPN
ecletica-1329	512	75	;	;	PUNCT
ecletica-1329	512	76	park	park	PROPN
ecletica-1329	512	77	,	,	PUNCT
ecletica-1329	512	78	y.	y.	PROPN
ecletica-1329	512	79	s.	s.	PROPN
ecletica-1329	512	80	;	;	PUNCT
ecletica-1329	512	81	kim	kim	PROPN
ecletica-1329	512	82	,	,	PUNCT
ecletica-1329	512	83	w.	w.	PROPN
ecletica-1329	512	84	s.	s.	PROPN
ecletica-1329	512	85	;	;	PUNCT
ecletica-1329	512	86	lee	lee	PROPN
ecletica-1329	512	87	,	,	PUNCT
ecletica-1329	512	88	d.	d.	PROPN
ecletica-1329	512	89	h.	h.	PROPN
ecletica-1329	512	90	;	;	PUNCT
ecletica-1329	512	91	lee	lee	PROPN
ecletica-1329	512	92	,	,	PUNCT
ecletica-1329	512	93	j.	j.	PROPN
ecletica-1329	512	94	s.	s.	PROPN
ecletica-1329	512	95	;	;	PUNCT
ecletica-1329	512	96	miller	miller	PROPN
ecletica-1329	512	97	,	,	PUNCT
ecletica-1329	512	98	v.	v.	PROPN
ecletica-1329	512	99	a.	a.	NOUN
ecletica-1329	512	100	;	;	PUNCT
ecletica-1329	512	101	arcila	arcila	PROPN
ecletica-1329	512	102	,	,	PUNCT
ecletica-1329	512	103	m.	m.	NOUN
ecletica-1329	512	104	;	;	PUNCT
ecletica-1329	512	105	ladanyi	ladanyi	PROPN
ecletica-1329	512	106	,	,	PUNCT
ecletica-1329	512	107	m.	m.	NOUN
ecletica-1329	512	108	;	;	PUNCT
ecletica-1329	512	109	moonsamy	moonsamy	NOUN
ecletica-1329	512	110	,	,	PUNCT
ecletica-1329	512	111	p.	p.	NOUN
ecletica-1329	512	112	;	;	PUNCT
ecletica-1329	512	113	sawyers	sawyer	NOUN
ecletica-1329	512	114	,	,	PUNCT
ecletica-1329	512	115	c.	c.	PROPN
ecletica-1329	512	116	;	;	PUNCT
ecletica-1329	512	117	boggon	boggon	PROPN
ecletica-1329	512	118	,	,	PUNCT
ecletica-1329	512	119	t.	t.	PROPN
ecletica-1329	512	120	j.	j.	PROPN
ecletica-1329	512	121	;	;	PUNCT
ecletica-1329	512	122	ma	ma	PROPN
ecletica-1329	512	123	,	,	PUNCT
ecletica-1329	512	124	p.	p.	PROPN
ecletica-1329	512	125	c.	c.	PROPN
ecletica-1329	512	126	;	;	PUNCT
ecletica-1329	512	127	costa	costa	PROPN
ecletica-1329	512	128	,	,	PUNCT
ecletica-1329	512	129	c.	c.	PROPN
ecletica-1329	512	130	;	;	PUNCT
ecletica-1329	512	131	taron	taron	NOUN
ecletica-1329	512	132	,	,	PUNCT
ecletica-1329	512	133	m.	m.	NOUN
ecletica-1329	512	134	;	;	PUNCT
ecletica-1329	512	135	rosell	rosell	PROPN
ecletica-1329	512	136	,	,	PUNCT
ecletica-1329	512	137	r.	r.	PROPN
ecletica-1329	512	138	;	;	PUNCT
ecletica-1329	512	139	halmos	halmos	PROPN
ecletica-1329	512	140	,	,	PUNCT
ecletica-1329	512	141	b.	b.	PROPN
ecletica-1329	512	142	;	;	PUNCT
ecletica-1329	512	143	bivona	bivona	PROPN
ecletica-1329	512	144	,	,	PUNCT
ecletica-1329	512	145	t.	t.	NOUN
ecletica-1329	512	146	g.	g.	PROPN
ecletica-1329	512	147	activation	activation	NOUN
ecletica-1329	512	148	of	of	ADP
ecletica-1329	512	149	the	the	DET
ecletica-1329	512	150	axl	axl	PROPN
ecletica-1329	512	151	kinase	kinase	PROPN
ecletica-1329	512	152	causes	cause	VERB
ecletica-1329	512	153	resistance	resistance	NOUN
ecletica-1329	512	154	to	to	ADP
ecletica-1329	512	155	egfr	egfr	ADV
ecletica-1329	512	156	-	-	PUNCT
ecletica-1329	512	157	targeted	target	VERB
ecletica-1329	512	158	therapy	therapy	NOUN
ecletica-1329	512	159	in	in	ADP
ecletica-1329	512	160	lung	lung	NOUN
ecletica-1329	512	161	cancer	cancer	NOUN
ecletica-1329	512	162	.	.	PUNCT
ecletica-1329	513	1	nat	nat	PROPN
ecletica-1329	513	2	.	.	PUNCT
ecletica-1329	514	1	genet	genet	PROPN
ecletica-1329	514	2	.	.	PUNCT
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ecletica-1329	515	2	,	,	PUNCT
ecletica-1329	515	3	44	44	NUM
ecletica-1329	515	4	(	(	PUNCT
ecletica-1329	515	5	8)	8)	NUM
ecletica-1329	515	6	,	,	PUNCT
ecletica-1329	515	7	852–860	852–860	NUM
ecletica-1329	515	8	.	.	PUNCT
ecletica-1329	516	1	https://doi.org/10.1038/ng.2330	https://doi.org/10.1038/ng.2330	ADP
ecletica-1329	516	2	https://revista.iq.unesp.br/index.php/ecletica	https://revista.iq.unesp.br/index.php/ecletica	PROPN
ecletica-1329	516	3	https://doi.org/10.26850/1678-4618eqj.v48.1.2023.p55-71	https://doi.org/10.26850/1678-4618eqj.v48.1.2023.p55-71	PROPN
ecletica-1329	516	4	https://doi.org/10.1126/scitranslmed.3007205	https://doi.org/10.1126/scitranslmed.3007205	NOUN
ecletica-1329	516	5	https://doi.org/10.1126/scitranslmed.3007205	https://doi.org/10.1126/scitranslmed.3007205	PROPN
ecletica-1329	516	6	https://doi.org/10.1126/scitranslmed.3007205	https://doi.org/10.1126/scitranslmed.3007205	PROPN
ecletica-1329	516	7	https://doi.org/10.1126/scitranslmed.3007205	https://doi.org/10.1126/scitranslmed.3007205	PROPN
ecletica-1329	516	8	https://doi.org/10.1126/scitranslmed.3007205	https://doi.org/10.1126/scitranslmed.3007205	PROPN
ecletica-1329	516	9	https://doi.org/10.1126/scitranslmed.3007205	https://doi.org/10.1126/scitranslmed.3007205	PROPN
ecletica-1329	516	10	https://doi.org/10.1126/scitranslmed.3007205	https://doi.org/10.1126/scitranslmed.3007205	NOUN
ecletica-1329	516	11	https://doi.org/10.1038/ng.2330	https://doi.org/10.1038/ng.2330	ADP
ecletica-1329	516	12	https://doi.org/10.1038/ng.2330	https://doi.org/10.1038/ng.2330	ADP
ecletica-1329	516	13	https://doi.org/10.1038/ng.2330	https://doi.org/10.1038/ng.2330	ADP
ecletica-1329	516	14	https://doi.org/10.1038/ng.2330	https://doi.org/10.1038/ng.2330	ADP
ecletica-1329	516	15	https://doi.org/10.1038/ng.2330	https://doi.org/10.1038/ng.2330	ADP
ecletica-1329	516	16	https://doi.org/10.1038/ng.2330	https://doi.org/10.1038/ng.2330	ADP
ecletica-1329	516	17	https://doi.org/10.1038/ng.2330	https://doi.org/10.1038/ng.2330	ADP
ecletica-1329	516	18	https://doi.org/10.1038/ng.2330	https://doi.org/10.1038/ng.2330	ADP
ecletica-1329	516	19	https://doi.org/10.1038/ng.2330	https://doi.org/10.1038/ng.2330	ADP
ecletica-1329	516	20	https://doi.org/10.1038/ng.2330	https://doi.org/10.1038/ng.2330	X