id	sid	tid	token	lemma	pos
ecletica-1594	1	1	eclet	eclet	VERB
ecletica-1594	1	2	.	.	PUNCT
ecletica-1594	2	1	quim	quim	ADJ
ecletica-1594	2	2	.	.	PUNCT
ecletica-1594	3	1	50	50	NUM
ecletica-1594	3	2	|	|	ADV
ecletica-1594	3	3	e-1594	e-1594	NOUN
ecletica-1594	3	4	,	,	PUNCT
ecletica-1594	3	5	2025	2025	NUM
ecletica-1594	3	6	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	NOUN
ecletica-1594	3	7	issn	issn	VERB
ecletica-1594	3	8	1678	1678	NUM
ecletica-1594	3	9	-	-	SYM
ecletica-1594	3	10	4618	4618	NUM
ecletica-1594	3	11	page	page	NOUN
ecletica-1594	3	12	1/14	1/14	NUM
ecletica-1594	3	13	1university	1university	NUM
ecletica-1594	3	14	of	of	ADP
ecletica-1594	3	15	ibadan	ibadan	PROPN
ecletica-1594	3	16	,	,	PUNCT
ecletica-1594	3	17	department	department	NOUN
ecletica-1594	3	18	of	of	ADP
ecletica-1594	3	19	chemistry	chemistry	NOUN
ecletica-1594	3	20	,	,	PUNCT
ecletica-1594	3	21	ibadan	ibadan	PROPN
ecletica-1594	3	22	,	,	PUNCT
ecletica-1594	3	23	nigeria	nigeria	PROPN
ecletica-1594	3	24	.	.	PUNCT
ecletica-1594	4	1	2federal	2federal	ADJ
ecletica-1594	4	2	university	university	NOUN
ecletica-1594	4	3	of	of	ADP
ecletica-1594	4	4	lokoja	lokoja	PROPN
ecletica-1594	4	5	,	,	PUNCT
ecletica-1594	4	6	department	department	NOUN
ecletica-1594	4	7	of	of	ADP
ecletica-1594	4	8	chemistry	chemistry	NOUN
ecletica-1594	4	9	,	,	PUNCT
ecletica-1594	4	10	lokoja	lokoja	PROPN
ecletica-1594	4	11	,	,	PUNCT
ecletica-1594	4	12	nigeria	nigeria	PROPN
ecletica-1594	4	13	.	.	PUNCT
ecletica-1594	5	1	3ladoke	3ladoke	NUM
ecletica-1594	5	2	akintola	akintola	PROPN
ecletica-1594	5	3	university	university	PROPN
ecletica-1594	5	4	of	of	ADP
ecletica-1594	5	5	technology	technology	NOUN
ecletica-1594	5	6	,	,	PUNCT
ecletica-1594	5	7	department	department	NOUN
ecletica-1594	5	8	of	of	ADP
ecletica-1594	5	9	pure	pure	ADJ
ecletica-1594	5	10	and	and	CCONJ
ecletica-1594	5	11	applied	applied	ADJ
ecletica-1594	5	12	chemistry	chemistry	NOUN
ecletica-1594	5	13	,	,	PUNCT
ecletica-1594	5	14	ogbomoso	ogbomoso	NOUN
ecletica-1594	5	15	,	,	PUNCT
ecletica-1594	5	16	nigeria	nigeria	PROPN
ecletica-1594	5	17	.	.	PUNCT
ecletica-1594	6	1	4osun	4osun	NOUN
ecletica-1594	6	2	state	state	PROPN
ecletica-1594	6	3	university	university	PROPN
ecletica-1594	6	4	,	,	PUNCT
ecletica-1594	6	5	department	department	NOUN
ecletica-1594	6	6	of	of	ADP
ecletica-1594	6	7	pure	pure	ADJ
ecletica-1594	6	8	and	and	CCONJ
ecletica-1594	6	9	applied	applied	ADJ
ecletica-1594	6	10	chemistry	chemistry	NOUN
ecletica-1594	6	11	,	,	PUNCT
ecletica-1594	6	12	osogbo	osogbo	VERB
ecletica-1594	6	13	,	,	PUNCT
ecletica-1594	6	14	nigeria	nigeria	PROPN
ecletica-1594	6	15	.	.	PUNCT
ecletica-1594	7	1	5university	5university	NUM
ecletica-1594	7	2	of	of	ADP
ecletica-1594	7	3	ilesa	ilesa	PROPN
ecletica-1594	7	4	,	,	PUNCT
ecletica-1594	7	5	department	department	NOUN
ecletica-1594	7	6	of	of	ADP
ecletica-1594	7	7	industrial	industrial	ADJ
ecletica-1594	7	8	chemistry	chemistry	NOUN
ecletica-1594	7	9	,	,	PUNCT
ecletica-1594	7	10	ilesa	ilesa	PROPN
ecletica-1594	7	11	,	,	PUNCT
ecletica-1594	7	12	nigeria	nigeria	PROPN
ecletica-1594	7	13	.	.	PUNCT
ecletica-1594	8	1	6university	6university	NUM
ecletica-1594	8	2	of	of	ADP
ecletica-1594	8	3	ilesa	ilesa	NOUN
ecletica-1594	8	4	,	,	PUNCT
ecletica-1594	8	5	good	good	ADJ
ecletica-1594	8	6	health	health	NOUN
ecletica-1594	8	7	and	and	CCONJ
ecletica-1594	8	8	wellbeing	wellbee	VERB
ecletica-1594	8	9	research	research	NOUN
ecletica-1594	8	10	clusters	cluster	NOUN
ecletica-1594	8	11	,	,	PUNCT
ecletica-1594	8	12	ilesa	ilesa	PROPN
ecletica-1594	8	13	,	,	PUNCT
ecletica-1594	8	14	nigeria	nigeria	PROPN
ecletica-1594	8	15	.	.	PUNCT
ecletica-1594	9	1	+	+	PUNCT
ecletica-1594	9	2	corresponding	corresponding	ADJ
ecletica-1594	9	3	author	author	NOUN
ecletica-1594	9	4	:	:	PUNCT
ecletica-1594	9	5	banjo	banjo	NOUN
ecletica-1594	9	6	semire	semire	NOUN
ecletica-1594	9	7	,	,	PUNCT
ecletica-1594	9	8	phone	phone	NOUN
ecletica-1594	9	9	:	:	PUNCT
ecletica-1594	9	10	+2348038269809	+2348038269809	NUM
ecletica-1594	9	11	,	,	PUNCT
ecletica-1594	9	12	email	email	NOUN
ecletica-1594	9	13	address	address	NOUN
ecletica-1594	9	14	:	:	PUNCT
ecletica-1594	9	15	bsemire@lautech.edu.ng	bsemire@lautech.edu.ng	ADJ
ecletica-1594	9	16	original	original	ADJ
ecletica-1594	9	17	article	article	NOUN
ecletica-1594	9	18	molecular	molecular	ADJ
ecletica-1594	9	19	modeling	modeling	NOUN
ecletica-1594	9	20	and	and	CCONJ
ecletica-1594	9	21	pharmacokinetics	pharmacokinetic	NOUN
ecletica-1594	9	22	studies	study	NOUN
ecletica-1594	9	23	of	of	ADP
ecletica-1594	9	24	sulfamidophosphonate	sulfamidophosphonate	ADJ
ecletica-1594	9	25	derivatives	derivative	NOUN
ecletica-1594	9	26	as	as	ADP
ecletica-1594	9	27	potential	potential	ADJ
ecletica-1594	9	28	candidate	candidate	NOUN
ecletica-1594	9	29	against	against	ADP
ecletica-1594	9	30	staphylococcus	staphylococcus	NOUN
ecletica-1594	9	31	aureus	aureus	PROPN
ecletica-1594	9	32	abimbola	abimbola	PROPN
ecletica-1594	9	33	modupe	modupe	VERB
ecletica-1594	9	34	olatunde1	olatunde1	NOUN
ecletica-1594	9	35	,	,	PUNCT
ecletica-1594	9	36	kehinde	kehinde	PROPN
ecletica-1594	9	37	gabriel	gabriel	PROPN
ecletica-1594	9	38	obiyenwa2	obiyenwa2	PROPN
ecletica-1594	9	39	,	,	PUNCT
ecletica-1594	9	40	tofunmi	tofunmi	PROPN
ecletica-1594	9	41	emmanuel	emmanuel	PROPN
ecletica-1594	9	42	oladuji3	oladuji3	PROPN
ecletica-1594	9	43	,	,	PUNCT
ecletica-1594	9	44	dayo	dayo	NOUN
ecletica-1594	9	45	felix	felix	NOUN
ecletica-1594	9	46	latona4	latona4	NOUN
ecletica-1594	9	47	,	,	PUNCT
ecletica-1594	9	48	abel	abel	PROPN
ecletica-1594	9	49	kolawole	kolawole	PROPN
ecletica-1594	10	1	oyebamiji5,6	oyebamiji5,6	PROPN
ecletica-1594	10	2	,	,	PUNCT
ecletica-1594	10	3	nathaniel	nathaniel	PROPN
ecletica-1594	10	4	oladoye	oladoye	PROPN
ecletica-1594	10	5	olatunji3	olatunji3	PROPN
ecletica-1594	10	6	,	,	PUNCT
ecletica-1594	10	7	banjo	banjo	NOUN
ecletica-1594	10	8	semire2,3	semire2,3	PROPN
ecletica-1594	10	9	+	+	PROPN
ecletica-1594	10	10	abstract	abstract	ADJ
ecletica-1594	10	11	in	in	ADP
ecletica-1594	10	12	silico	silico	NOUN
ecletica-1594	10	13	methods	method	NOUN
ecletica-1594	10	14	were	be	AUX
ecletica-1594	10	15	used	use	VERB
ecletica-1594	10	16	in	in	ADP
ecletica-1594	10	17	this	this	DET
ecletica-1594	10	18	paper	paper	NOUN
ecletica-1594	10	19	to	to	PART
ecletica-1594	10	20	assess	assess	VERB
ecletica-1594	10	21	the	the	DET
ecletica-1594	10	22	anti	anti	ADJ
ecletica-1594	10	23	-	-	ADJ
ecletica-1594	10	24	bacterial	bacterial	ADJ
ecletica-1594	10	25	activity	activity	NOUN
ecletica-1594	10	26	of	of	ADP
ecletica-1594	10	27	sulfamidophosphonate	sulfamidophosphonate	ADJ
ecletica-1594	10	28	derivatives	derivative	NOUN
ecletica-1594	10	29	against	against	ADP
ecletica-1594	10	30	staphylococcus	staphylococcus	NOUN
ecletica-1594	10	31	aureus	aureus	NOUN
ecletica-1594	10	32	proteins	protein	NOUN
ecletica-1594	10	33	(	(	PUNCT
ecletica-1594	10	34	1xsd	1xsd	NOUN
ecletica-1594	10	35	and	and	CCONJ
ecletica-1594	10	36	4wk3	4wk3	NUM
ecletica-1594	10	37	)	)	PUNCT
ecletica-1594	10	38	using	use	VERB
ecletica-1594	10	39	molecular	molecular	ADJ
ecletica-1594	10	40	docking	docking	NOUN
ecletica-1594	10	41	and	and	CCONJ
ecletica-1594	10	42	admet	admet	ADJ
ecletica-1594	10	43	analysis	analysis	NOUN
ecletica-1594	10	44	.	.	PUNCT
ecletica-1594	11	1	the	the	DET
ecletica-1594	11	2	results	result	NOUN
ecletica-1594	11	3	showed	show	VERB
ecletica-1594	11	4	that	that	SCONJ
ecletica-1594	11	5	binding	bind	VERB
ecletica-1594	11	6	affinity	affinity	NOUN
ecletica-1594	11	7	(	(	PUNCT
ecletica-1594	11	8	δg	δg	VERB
ecletica-1594	11	9	kj	kj	PROPN
ecletica-1594	11	10	/	/	SYM
ecletica-1594	11	11	mol	mol	PROPN
ecletica-1594	11	12	)	)	PUNCT
ecletica-1594	11	13	ranged	range	VERB
ecletica-1594	11	14	from	from	ADP
ecletica-1594	11	15	–	–	PUNCT
ecletica-1594	11	16	4.1(nam	4.1(nam	NUM
ecletica-1594	11	17	)	)	PUNCT
ecletica-1594	11	18	to	to	ADP
ecletica-1594	11	19	–	–	PUNCT
ecletica-1594	11	20	7.1	7.1	NUM
ecletica-1594	11	21	kj	kj	PROPN
ecletica-1594	11	22	/	/	SYM
ecletica-1594	11	23	mol	mol	PROPN
ecletica-1594	11	24	(	(	PUNCT
ecletica-1594	11	25	nal	nal	NOUN
ecletica-1594	11	26	)	)	PUNCT
ecletica-1594	11	27	for	for	ADP
ecletica-1594	11	28	1xsd	1xsd	NUM
ecletica-1594	11	29	,	,	PUNCT
ecletica-1594	11	30	and	and	CCONJ
ecletica-1594	11	31	–	–	PUNCT
ecletica-1594	11	32	5.0	5.0	NUM
ecletica-1594	11	33	(	(	PUNCT
ecletica-1594	11	34	nae	nae	PROPN
ecletica-1594	11	35	)	)	PUNCT
ecletica-1594	11	36	to	to	ADP
ecletica-1594	11	37	–	–	PUNCT
ecletica-1594	11	38	6.7	6.7	NUM
ecletica-1594	11	39	kj	kj	PROPN
ecletica-1594	11	40	/	/	SYM
ecletica-1594	11	41	mol	mol	PROPN
ecletica-1594	11	42	(	(	PUNCT
ecletica-1594	11	43	nam	nam	PROPN
ecletica-1594	11	44	)	)	PUNCT
ecletica-1594	11	45	for	for	ADP
ecletica-1594	11	46	4wk3	4wk3	NUM
ecletica-1594	11	47	.	.	PUNCT
ecletica-1594	12	1	therefore	therefore	ADV
ecletica-1594	12	2	,	,	PUNCT
ecletica-1594	12	3	compounds	compound	VERB
ecletica-1594	12	4	nah	nah	INTJ
ecletica-1594	12	5	,	,	PUNCT
ecletica-1594	12	6	nal	nal	PROPN
ecletica-1594	12	7	,	,	PUNCT
ecletica-1594	12	8	nan	nan	PROPN
ecletica-1594	12	9	,	,	PUNCT
ecletica-1594	12	10	nai	nai	PROPN
ecletica-1594	12	11	,	,	PUNCT
ecletica-1594	12	12	naj	naj	PROPN
ecletica-1594	12	13	,	,	PUNCT
ecletica-1594	12	14	nak	nak	PROPN
ecletica-1594	12	15	,	,	PUNCT
ecletica-1594	12	16	5ad	5ad	PROPN
ecletica-1594	12	17	and	and	CCONJ
ecletica-1594	12	18	nam	nam	NOUN
ecletica-1594	12	19	could	could	AUX
ecletica-1594	12	20	be	be	AUX
ecletica-1594	12	21	more	more	ADV
ecletica-1594	12	22	desirable	desirable	ADJ
ecletica-1594	12	23	as	as	ADP
ecletica-1594	12	24	inhibitors	inhibitor	NOUN
ecletica-1594	12	25	than	than	ADP
ecletica-1594	12	26	penicillin	penicillin	NOUN
ecletica-1594	12	27	(	(	PUNCT
ecletica-1594	12	28	–	–	PUNCT
ecletica-1594	12	29	6.0	6.0	NUM
ecletica-1594	12	30	kj	kj	NOUN
ecletica-1594	12	31	/	/	SYM
ecletica-1594	12	32	mol	mol	NOUN
ecletica-1594	12	33	for	for	ADP
ecletica-1594	12	34	1xsd	1xsd	NUM
ecletica-1594	12	35	and	and	CCONJ
ecletica-1594	12	36	–	–	PUNCT
ecletica-1594	12	37	5.4	5.4	NUM
ecletica-1594	12	38	kj	kj	PROPN
ecletica-1594	12	39	/	/	SYM
ecletica-1594	12	40	mol	mol	NOUN
ecletica-1594	12	41	for	for	ADP
ecletica-1594	12	42	4wk3	4wk3	NUM
ecletica-1594	12	43	)	)	PUNCT
ecletica-1594	12	44	in	in	ADP
ecletica-1594	12	45	the	the	DET
ecletica-1594	12	46	treatment	treatment	NOUN
ecletica-1594	12	47	of	of	ADP
ecletica-1594	12	48	staphylococcus	staphylococcus	NOUN
ecletica-1594	12	49	aureus	aureus	NOUN
ecletica-1594	12	50	;	;	PUNCT
ecletica-1594	12	51	but	but	CCONJ
ecletica-1594	12	52	admet	admet	PROPN
ecletica-1594	12	53	profile	profile	PROPN
ecletica-1594	12	54	revealed	reveal	VERB
ecletica-1594	12	55	that	that	SCONJ
ecletica-1594	12	56	compounds	compound	VERB
ecletica-1594	12	57	naf	naf	PROPN
ecletica-1594	12	58	,	,	PUNCT
ecletica-1594	12	59	nai	nai	PROPN
ecletica-1594	12	60	,	,	PUNCT
ecletica-1594	12	61	nak	nak	PROPN
ecletica-1594	12	62	nan	nan	PROPN
ecletica-1594	12	63	and	and	CCONJ
ecletica-1594	12	64	5ac	5ac	ADJ
ecletica-1594	12	65	present	present	ADJ
ecletica-1594	12	66	attractive	attractive	ADJ
ecletica-1594	12	67	pharmacokinetic	pharmacokinetic	ADJ
ecletica-1594	12	68	properties	property	NOUN
ecletica-1594	12	69	.	.	PUNCT
ecletica-1594	13	1	in	in	ADP
ecletica-1594	13	2	this	this	DET
ecletica-1594	13	3	study	study	NOUN
ecletica-1594	13	4	,	,	PUNCT
ecletica-1594	13	5	compounds	compound	VERB
ecletica-1594	13	6	nah	nah	INTJ
ecletica-1594	13	7	,	,	PUNCT
ecletica-1594	13	8	nal	nal	PROPN
ecletica-1594	13	9	,	,	PUNCT
ecletica-1594	13	10	nai	nai	NOUN
ecletica-1594	13	11	and	and	CCONJ
ecletica-1594	13	12	naj	naj	PROPN
ecletica-1594	13	13	exhibited	exhibit	VERB
ecletica-1594	13	14	stronger	strong	ADJ
ecletica-1594	13	15	affinities	affinity	NOUN
ecletica-1594	13	16	than	than	ADP
ecletica-1594	13	17	the	the	DET
ecletica-1594	13	18	standard	standard	NOUN
ecletica-1594	13	19	(	(	PUNCT
ecletica-1594	13	20	penicillin	penicillin	NOUN
ecletica-1594	13	21	)	)	PUNCT
ecletica-1594	13	22	against	against	ADP
ecletica-1594	13	23	blai	blai	PROPN
ecletica-1594	13	24	repressor	repressor	NOUN
ecletica-1594	13	25	in	in	ADP
ecletica-1594	13	26	complex	complex	NOUN
ecletica-1594	13	27	with	with	ADP
ecletica-1594	13	28	dna	dna	PROPN
ecletica-1594	13	29	(	(	PUNCT
ecletica-1594	13	30	pdb	pdb	PROPN
ecletica-1594	13	31	i	i	PROPN
ecletica-1594	13	32	d	d	PROPN
ecletica-1594	13	33	:	:	PUNCT
ecletica-1594	13	34	1xsd	1xsd	X
ecletica-1594	13	35	)	)	PUNCT
ecletica-1594	13	36	suggesting	suggest	VERB
ecletica-1594	13	37	better	well	ADJ
ecletica-1594	13	38	inhibitory	inhibitory	ADJ
ecletica-1594	13	39	potential	potential	NOUN
ecletica-1594	13	40	than	than	ADP
ecletica-1594	13	41	the	the	DET
ecletica-1594	13	42	standard	standard	ADJ
ecletica-1594	13	43	drug	drug	NOUN
ecletica-1594	13	44	.	.	PUNCT
ecletica-1594	14	1	article	article	NOUN
ecletica-1594	14	2	history	history	NOUN
ecletica-1594	14	3	received	receive	VERB
ecletica-1594	14	4	september	september	PROPN
ecletica-1594	14	5	02	02	NUM
ecletica-1594	14	6	,	,	PUNCT
ecletica-1594	14	7	2024	2024	NUM
ecletica-1594	14	8	accepted	accept	VERB
ecletica-1594	14	9	december	december	PROPN
ecletica-1594	14	10	19	19	NUM
ecletica-1594	14	11	,	,	PUNCT
ecletica-1594	14	12	2024	2024	NUM
ecletica-1594	14	13	published	publish	VERB
ecletica-1594	14	14	june	june	PROPN
ecletica-1594	14	15	26	26	NUM
ecletica-1594	14	16	,	,	PUNCT
ecletica-1594	14	17	2025	2025	NUM
ecletica-1594	14	18	keywords	keyword	NOUN
ecletica-1594	14	19	1	1	NUM
ecletica-1594	14	20	.	.	PUNCT
ecletica-1594	14	21	phytochemicals	phytochemical	NOUN
ecletica-1594	14	22	;	;	PUNCT
ecletica-1594	14	23	2	2	X
ecletica-1594	14	24	.	.	X
ecletica-1594	14	25	bacteria	bacteria	NOUN
ecletica-1594	14	26	;	;	PUNCT
ecletica-1594	14	27	3	3	X
ecletica-1594	14	28	.	.	NOUN
ecletica-1594	14	29	interactions	interaction	NOUN
ecletica-1594	14	30	;	;	PUNCT
ecletica-1594	15	1	4	4	X
ecletica-1594	15	2	.	.	X
ecletica-1594	15	3	admet	admet	PROPN
ecletica-1594	15	4	.	.	PUNCT
ecletica-1594	16	1	section	section	NOUN
ecletica-1594	16	2	editors	editor	NOUN
ecletica-1594	16	3	assis	assis	PROPN
ecletica-1594	16	4	vicente	vicente	PROPN
ecletica-1594	16	5	benedetti	benedetti	PROPN
ecletica-1594	16	6	highlights	highlight	VERB
ecletica-1594	16	7	the	the	DET
ecletica-1594	16	8	antibacterial	antibacterial	ADJ
ecletica-1594	16	9	activity	activity	NOUN
ecletica-1594	16	10	of	of	ADP
ecletica-1594	16	11	sulfamidophosphonate	sulfamidophosphonate	ADJ
ecletica-1594	16	12	derivatives	derivative	NOUN
ecletica-1594	16	13	was	be	AUX
ecletica-1594	16	14	evaluated	evaluate	VERB
ecletica-1594	16	15	.	.	PUNCT
ecletica-1594	17	1	descriptors	descriptor	NOUN
ecletica-1594	17	2	found	find	VERB
ecletica-1594	17	3	from	from	ADP
ecletica-1594	17	4	optimized	optimize	VERB
ecletica-1594	17	5	sulfamidophosphonate	sulfamidophosphonate	NOUN
ecletica-1594	17	6	derivatives	derivative	NOUN
ecletica-1594	17	7	were	be	AUX
ecletica-1594	17	8	identified	identify	VERB
ecletica-1594	17	9	.	.	PUNCT
ecletica-1594	18	1	nonbonding	nonbonde	VERB
ecletica-1594	18	2	interactions	interaction	NOUN
ecletica-1594	18	3	between	between	ADP
ecletica-1594	18	4	drugs	drug	NOUN
ecletica-1594	18	5	and	and	CCONJ
ecletica-1594	18	6	the	the	DET
ecletica-1594	18	7	studied	study	VERB
ecletica-1594	18	8	targets	target	NOUN
ecletica-1594	18	9	were	be	AUX
ecletica-1594	18	10	observed	observe	VERB
ecletica-1594	18	11	.	.	PUNCT
ecletica-1594	19	1	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	NOUN
ecletica-1594	19	2	https://ror.org/03wx2rr30	https://ror.org/03wx2rr30	SCONJ
ecletica-1594	19	3	https://ror.org/018ced875	https://ror.org/018ced875	ADJ
ecletica-1594	19	4	https://ror.org/043hyzt56	https://ror.org/043hyzt56	VERB
ecletica-1594	19	5	https://ror.org/043hyzt56	https://ror.org/043hyzt56	NOUN
ecletica-1594	19	6	https://ror.org/00e16h982	https://ror.org/00e16h982	X
ecletica-1594	19	7	https://ror.org/0019ead15	https://ror.org/0019ead15	PROPN
ecletica-1594	19	8	https://ror.org/0019ead15	https://ror.org/0019ead15	PROPN
ecletica-1594	19	9	https://ror.org/0019ead15	https://ror.org/0019ead15	PROPN
ecletica-1594	19	10	mailto:abimbolatunde1@gmail.com	mailto:abimbolatunde1@gmail.com	PROPN
ecletica-1594	19	11	mailto:obiyenwagab@gmail.com	mailto:obiyenwagab@gmail.com	PROPN
ecletica-1594	19	12	mailto:oladutoem@gmail.com	mailto:oladutoem@gmail.com	PROPN
ecletica-1594	19	13	mailto:dayo.felix@uniosun.edu.ng	mailto:dayo.felix@uniosun.edu.ng	X
ecletica-1594	19	14	mailto:abeloyebamiji@gmail.com	mailto:abeloyebamiji@gmail.com	PROPN
ecletica-1594	20	1	mailto:olatuj@gmail.com	mailto:olatuj@gmail.com	X
ecletica-1594	20	2	mailto:bsemire@lauctech.edu.ng	mailto:bsemire@lauctech.edu.ng	NOUN
ecletica-1594	20	3	https://orcid.org/0000-0002-2545-7723	https://orcid.org/0000-0002-2545-7723	ADJ
ecletica-1594	20	4	https://orcid.org/0000-0003-0184-8807	https://orcid.org/0000-0003-0184-8807	NOUN
ecletica-1594	20	5	https://orcid.org/0009-0008-9189-4607	https://orcid.org/0009-0008-9189-4607	PROPN
ecletica-1594	20	6	https://orcid.org/0000-0002-2722-6734	https://orcid.org/0000-0002-2722-6734	ADP
ecletica-1594	20	7	https://orcid.org/0000-0002-8932-6327	https://orcid.org/0000-0002-8932-6327	INTJ
ecletica-1594	20	8	https://orcid.org/0009-0006-4026-3384	https://orcid.org/0009-0006-4026-3384	PRON
ecletica-1594	20	9	https://orcid.org/0000-0002-4173-9165	https://orcid.org/0000-0002-4173-9165	NOUN
ecletica-1594	20	10	original	original	ADJ
ecletica-1594	20	11	article	article	NOUN
ecletica-1594	20	12	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	X
ecletica-1594	20	13	issn	issn	VERB
ecletica-1594	20	14	1678	1678	NUM
ecletica-1594	20	15	-	-	SYM
ecletica-1594	20	16	4618	4618	NUM
ecletica-1594	20	17	page	page	NOUN
ecletica-1594	20	18	2/14	2/14	NUM
ecletica-1594	20	19	1	1	NUM
ecletica-1594	20	20	.	.	PUNCT
ecletica-1594	21	1	introduction	introduction	NOUN
ecletica-1594	21	2	bacterial	bacterial	ADJ
ecletica-1594	21	3	diseases	disease	NOUN
ecletica-1594	21	4	such	such	ADJ
ecletica-1594	21	5	as	as	ADP
ecletica-1594	21	6	tuberculosis	tuberculosis	NOUN
ecletica-1594	21	7	,	,	PUNCT
ecletica-1594	21	8	anthrax	anthrax	NOUN
ecletica-1594	21	9	,	,	PUNCT
ecletica-1594	21	10	pneumonia	pneumonia	NOUN
ecletica-1594	21	11	and	and	CCONJ
ecletica-1594	21	12	osteomyelitis	osteomyelitis	NOUN
ecletica-1594	21	13	,	,	PUNCT
ecletica-1594	21	14	among	among	ADP
ecletica-1594	21	15	others	other	NOUN
ecletica-1594	21	16	,	,	PUNCT
ecletica-1594	21	17	are	be	AUX
ecletica-1594	21	18	deadly	deadly	ADJ
ecletica-1594	21	19	and	and	CCONJ
ecletica-1594	21	20	have	have	VERB
ecletica-1594	21	21	a	a	DET
ecletica-1594	21	22	significant	significant	ADJ
ecletica-1594	21	23	impact	impact	NOUN
ecletica-1594	21	24	on	on	ADP
ecletica-1594	21	25	public	public	ADJ
ecletica-1594	21	26	health	health	NOUN
ecletica-1594	21	27	.	.	PUNCT
ecletica-1594	22	1	staphylococcus	staphylococcus	NOUN
ecletica-1594	22	2	aureus	aureus	PROPN
ecletica-1594	22	3	is	be	AUX
ecletica-1594	22	4	both	both	CCONJ
ecletica-1594	22	5	a	a	DET
ecletica-1594	22	6	commensal	commensal	ADJ
ecletica-1594	22	7	bacterium	bacterium	NOUN
ecletica-1594	22	8	and	and	CCONJ
ecletica-1594	22	9	a	a	DET
ecletica-1594	22	10	human	human	ADJ
ecletica-1594	22	11	pathogen	pathogen	NOUN
ecletica-1594	22	12	.	.	PUNCT
ecletica-1594	23	1	about	about	ADV
ecletica-1594	23	2	30	30	NUM
ecletica-1594	23	3	%	%	NOUN
ecletica-1594	23	4	of	of	ADP
ecletica-1594	23	5	the	the	DET
ecletica-1594	23	6	human	human	ADJ
ecletica-1594	23	7	population	population	NOUN
ecletica-1594	23	8	is	be	AUX
ecletica-1594	23	9	colonized	colonize	VERB
ecletica-1594	23	10	with	with	ADP
ecletica-1594	23	11	s.	s.	PROPN
ecletica-1594	23	12	aureus	aureus	PROPN
ecletica-1594	23	13	(	(	PUNCT
ecletica-1594	23	14	wertheim	wertheim	PROPN
ecletica-1594	23	15	et	et	PROPN
ecletica-1594	23	16	al	al	PROPN
ecletica-1594	23	17	.	.	PROPN
ecletica-1594	23	18	,	,	PUNCT
ecletica-1594	23	19	2005	2005	NUM
ecletica-1594	23	20	)	)	PUNCT
ecletica-1594	23	21	.	.	PUNCT
ecletica-1594	24	1	in	in	ADP
ecletica-1594	24	2	the	the	DET
ecletica-1594	24	3	early	early	ADJ
ecletica-1594	24	4	1930s	1930	NOUN
ecletica-1594	24	5	,	,	PUNCT
ecletica-1594	24	6	doctors	doctor	NOUN
ecletica-1594	24	7	began	begin	VERB
ecletica-1594	24	8	to	to	PART
ecletica-1594	24	9	employ	employ	VERB
ecletica-1594	24	10	a	a	DET
ecletica-1594	24	11	more	more	ADV
ecletica-1594	24	12	efficient	efficient	ADJ
ecletica-1594	24	13	test	test	NOUN
ecletica-1594	24	14	to	to	PART
ecletica-1594	24	15	determine	determine	VERB
ecletica-1594	24	16	the	the	DET
ecletica-1594	24	17	presence	presence	NOUN
ecletica-1594	24	18	of	of	ADP
ecletica-1594	24	19	an	an	DET
ecletica-1594	24	20	s.	s.	PROPN
ecletica-1594	24	21	aureus	aureus	PROPN
ecletica-1594	24	22	infection	infection	NOUN
ecletica-1594	24	23	by	by	ADP
ecletica-1594	24	24	means	mean	NOUN
ecletica-1594	24	25	of	of	ADP
ecletica-1594	24	26	coagulase	coagulase	NOUN
ecletica-1594	24	27	testing	testing	NOUN
ecletica-1594	24	28	,	,	PUNCT
ecletica-1594	24	29	which	which	PRON
ecletica-1594	24	30	helped	help	VERB
ecletica-1594	24	31	to	to	PART
ecletica-1594	24	32	detect	detect	VERB
ecletica-1594	24	33	the	the	DET
ecletica-1594	24	34	enzyme	enzyme	NOUN
ecletica-1594	24	35	produced	produce	VERB
ecletica-1594	24	36	by	by	ADP
ecletica-1594	24	37	the	the	DET
ecletica-1594	24	38	bacterium	bacterium	NOUN
ecletica-1594	24	39	.	.	PUNCT
ecletica-1594	25	1	before	before	ADP
ecletica-1594	25	2	the	the	DET
ecletica-1594	25	3	1940s	1940	NOUN
ecletica-1594	25	4	,	,	PUNCT
ecletica-1594	25	5	s.	s.	PROPN
ecletica-1594	25	6	aureus	aureus	PROPN
ecletica-1594	25	7	infections	infection	NOUN
ecletica-1594	25	8	were	be	AUX
ecletica-1594	25	9	deadly	deadly	ADJ
ecletica-1594	25	10	in	in	ADP
ecletica-1594	25	11	most	most	ADJ
ecletica-1594	25	12	patients	patient	NOUN
ecletica-1594	25	13	until	until	ADP
ecletica-1594	25	14	the	the	DET
ecletica-1594	25	15	discovery	discovery	NOUN
ecletica-1594	25	16	of	of	ADP
ecletica-1594	25	17	penicillin	penicillin	PROPN
ecletica-1594	25	18	.	.	PUNCT
ecletica-1594	26	1	however	however	ADV
ecletica-1594	26	2	,	,	PUNCT
ecletica-1594	26	3	the	the	DET
ecletica-1594	26	4	meca	meca	PROPN
ecletica-1594	26	5	gene	gene	NOUN
ecletica-1594	26	6	carried	carry	VERB
ecletica-1594	26	7	by	by	ADP
ecletica-1594	26	8	methicillin	methicillin	NOUN
ecletica-1594	26	9	-	-	PUNCT
ecletica-1594	26	10	resistant	resistant	ADJ
ecletica-1594	26	11	staphylococcus	staphylococcus	NOUN
ecletica-1594	26	12	aureus	aureus	NOUN
ecletica-1594	26	13	(	(	PUNCT
ecletica-1594	26	14	mrsa	mrsa	NOUN
ecletica-1594	26	15	)	)	PUNCT
ecletica-1594	26	16	encodes	encode	VERB
ecletica-1594	26	17	the	the	DET
ecletica-1594	26	18	protein	protein	NOUN
ecletica-1594	26	19	pbp-2a	pbp-2a	NOUN
ecletica-1594	26	20	(	(	PUNCT
ecletica-1594	26	21	penicillin	penicillin	NOUN
ecletica-1594	26	22	-	-	PUNCT
ecletica-1594	26	23	binding	bind	VERB
ecletica-1594	26	24	protein	protein	NOUN
ecletica-1594	26	25	2a	2a	NUM
ecletica-1594	26	26	)	)	PUNCT
ecletica-1594	26	27	marked	mark	VERB
ecletica-1594	26	28	the	the	DET
ecletica-1594	26	29	outbreaks	outbreak	NOUN
ecletica-1594	26	30	of	of	ADP
ecletica-1594	26	31	the	the	DET
ecletica-1594	26	32	resistant	resistant	ADJ
ecletica-1594	26	33	strain	strain	NOUN
ecletica-1594	26	34	of	of	ADP
ecletica-1594	26	35	this	this	DET
ecletica-1594	26	36	bacterium	bacterium	NOUN
ecletica-1594	26	37	family	family	NOUN
ecletica-1594	26	38	(	(	PUNCT
ecletica-1594	26	39	orent	orent	NOUN
ecletica-1594	26	40	,	,	PUNCT
ecletica-1594	26	41	2006	2006	NUM
ecletica-1594	26	42	)	)	PUNCT
ecletica-1594	26	43	.	.	PUNCT
ecletica-1594	27	1	the	the	DET
ecletica-1594	27	2	pbp-2a	pbp-2a	PROPN
ecletica-1594	27	3	is	be	AUX
ecletica-1594	27	4	a	a	DET
ecletica-1594	27	5	penicillin	penicillin	NOUN
ecletica-1594	27	6	-	-	PUNCT
ecletica-1594	27	7	binding	bind	VERB
ecletica-1594	27	8	protein	protein	NOUN
ecletica-1594	27	9	(	(	PUNCT
ecletica-1594	27	10	pbp	pbp	NOUN
ecletica-1594	27	11	)	)	PUNCT
ecletica-1594	27	12	,	,	PUNCT
ecletica-1594	27	13	or	or	CCONJ
ecletica-1594	27	14	an	an	DET
ecletica-1594	27	15	essential	essential	ADJ
ecletica-1594	27	16	bacterial	bacterial	ADJ
ecletica-1594	27	17	cell	cell	NOUN
ecletica-1594	27	18	wall	wall	NOUN
ecletica-1594	27	19	enzyme	enzyme	NOUN
ecletica-1594	27	20	that	that	PRON
ecletica-1594	27	21	catalyzes	catalyze	VERB
ecletica-1594	27	22	the	the	DET
ecletica-1594	27	23	production	production	NOUN
ecletica-1594	27	24	of	of	ADP
ecletica-1594	27	25	the	the	DET
ecletica-1594	27	26	peptidoglycan	peptidoglycan	NOUN
ecletica-1594	27	27	in	in	ADP
ecletica-1594	27	28	the	the	DET
ecletica-1594	27	29	bacterial	bacterial	ADJ
ecletica-1594	27	30	cell	cell	NOUN
ecletica-1594	27	31	wall	wall	NOUN
ecletica-1594	27	32	.	.	PUNCT
ecletica-1594	28	1	pbp-2a	pbp-2a	PROPN
ecletica-1594	28	2	has	have	VERB
ecletica-1594	28	3	a	a	DET
ecletica-1594	28	4	lower	low	ADJ
ecletica-1594	28	5	affinity	affinity	NOUN
ecletica-1594	28	6	to	to	PART
ecletica-1594	28	7	bind	bind	VERB
ecletica-1594	28	8	to	to	ADP
ecletica-1594	28	9	beta	beta	NOUN
ecletica-1594	28	10	-	-	PUNCT
ecletica-1594	28	11	lactams	lactam	NOUN
ecletica-1594	28	12	(	(	PUNCT
ecletica-1594	28	13	and	and	CCONJ
ecletica-1594	28	14	other	other	ADJ
ecletica-1594	28	15	penicillinderived	penicillinderive	VERB
ecletica-1594	28	16	antibiotics	antibiotic	NOUN
ecletica-1594	28	17	)	)	PUNCT
ecletica-1594	28	18	when	when	SCONJ
ecletica-1594	28	19	compared	compare	VERB
ecletica-1594	28	20	to	to	ADP
ecletica-1594	28	21	other	other	ADJ
ecletica-1594	28	22	pbps	pbps	NOUN
ecletica-1594	28	23	.	.	PUNCT
ecletica-1594	29	1	the	the	DET
ecletica-1594	29	2	pbp-2a	pbp-2a	PROPN
ecletica-1594	29	3	continues	continue	VERB
ecletica-1594	29	4	to	to	PART
ecletica-1594	29	5	catalyze	catalyze	VERB
ecletica-1594	29	6	the	the	DET
ecletica-1594	29	7	synthesis	synthesis	NOUN
ecletica-1594	29	8	of	of	ADP
ecletica-1594	29	9	the	the	DET
ecletica-1594	29	10	bacterial	bacterial	ADJ
ecletica-1594	29	11	cell	cell	NOUN
ecletica-1594	29	12	wall	wall	NOUN
ecletica-1594	29	13	even	even	ADV
ecletica-1594	29	14	in	in	ADP
ecletica-1594	29	15	the	the	DET
ecletica-1594	29	16	presence	presence	NOUN
ecletica-1594	29	17	of	of	ADP
ecletica-1594	29	18	many	many	ADJ
ecletica-1594	29	19	antibiotics	antibiotic	NOUN
ecletica-1594	29	20	(	(	PUNCT
ecletica-1594	29	21	rasigade	rasigade	VERB
ecletica-1594	29	22	,	,	PUNCT
ecletica-1594	29	23	2014	2014	NUM
ecletica-1594	29	24	)	)	PUNCT
ecletica-1594	29	25	.	.	PUNCT
ecletica-1594	30	1	the	the	DET
ecletica-1594	30	2	chemistry	chemistry	NOUN
ecletica-1594	30	3	of	of	ADP
ecletica-1594	30	4	heterocyclic	heterocyclic	ADJ
ecletica-1594	30	5	molecules	molecule	NOUN
ecletica-1594	30	6	plays	play	VERB
ecletica-1594	30	7	a	a	DET
ecletica-1594	30	8	huge	huge	ADJ
ecletica-1594	30	9	role	role	NOUN
ecletica-1594	30	10	in	in	ADP
ecletica-1594	30	11	the	the	DET
ecletica-1594	30	12	development	development	NOUN
ecletica-1594	30	13	of	of	ADP
ecletica-1594	30	14	effective	effective	ADJ
ecletica-1594	30	15	drugs	drug	NOUN
ecletica-1594	30	16	for	for	ADP
ecletica-1594	30	17	bacterial	bacterial	ADJ
ecletica-1594	30	18	,	,	PUNCT
ecletica-1594	30	19	fungal	fungal	ADJ
ecletica-1594	30	20	and	and	CCONJ
ecletica-1594	30	21	viral	viral	ADJ
ecletica-1594	30	22	diseases	disease	NOUN
ecletica-1594	30	23	.	.	PUNCT
ecletica-1594	31	1	heterocyclic	heterocyclic	ADJ
ecletica-1594	31	2	compounds	compound	NOUN
ecletica-1594	31	3	are	be	AUX
ecletica-1594	31	4	the	the	DET
ecletica-1594	31	5	most	most	ADV
ecletica-1594	31	6	important	important	ADJ
ecletica-1594	31	7	organic	organic	ADJ
ecletica-1594	31	8	compounds	compound	NOUN
ecletica-1594	31	9	that	that	PRON
ecletica-1594	31	10	present	present	VERB
ecletica-1594	31	11	great	great	ADJ
ecletica-1594	31	12	interest	interest	NOUN
ecletica-1594	31	13	in	in	ADP
ecletica-1594	31	14	medicinal	medicinal	ADJ
ecletica-1594	31	15	chemistry	chemistry	NOUN
ecletica-1594	31	16	(	(	PUNCT
ecletica-1594	31	17	arora	arora	PROPN
ecletica-1594	31	18	et	et	PROPN
ecletica-1594	31	19	al	al	PROPN
ecletica-1594	31	20	.	.	PROPN
ecletica-1594	31	21	,	,	PUNCT
ecletica-1594	31	22	2012	2012	NUM
ecletica-1594	31	23	;	;	PUNCT
ecletica-1594	31	24	winum	winum	PROPN
ecletica-1594	31	25	et	et	PROPN
ecletica-1594	31	26	al	al	PROPN
ecletica-1594	31	27	.	.	PROPN
ecletica-1594	31	28	,	,	PUNCT
ecletica-1594	31	29	2006	2006	NUM
ecletica-1594	31	30	)	)	PUNCT
ecletica-1594	31	31	.	.	PUNCT
ecletica-1594	32	1	sulfonamide	sulfonamide	NOUN
ecletica-1594	32	2	derivatives	derivative	NOUN
ecletica-1594	32	3	,	,	PUNCT
ecletica-1594	32	4	a	a	DET
ecletica-1594	32	5	class	class	NOUN
ecletica-1594	32	6	of	of	ADP
ecletica-1594	32	7	heterocyclic	heterocyclic	ADJ
ecletica-1594	32	8	compounds	compound	NOUN
ecletica-1594	32	9	in	in	ADP
ecletica-1594	32	10	which	which	PRON
ecletica-1594	32	11	many	many	ADJ
ecletica-1594	32	12	this	this	DET
ecletica-1594	32	13	class	class	NOUN
ecletica-1594	32	14	compounds	compound	NOUN
ecletica-1594	32	15	have	have	AUX
ecletica-1594	32	16	been	be	AUX
ecletica-1594	32	17	reported	report	VERB
ecletica-1594	32	18	to	to	PART
ecletica-1594	32	19	show	show	VERB
ecletica-1594	32	20	biological	biological	ADJ
ecletica-1594	32	21	activities	activity	NOUN
ecletica-1594	32	22	such	such	ADJ
ecletica-1594	32	23	as	as	ADP
ecletica-1594	32	24	anti	anti	ADJ
ecletica-1594	32	25	-	-	ADJ
ecletica-1594	32	26	mycobacterial	mycobacterial	ADJ
ecletica-1594	32	27	,	,	PUNCT
ecletica-1594	32	28	anticonvulsant	anticonvulsant	ADJ
ecletica-1594	32	29	,	,	PUNCT
ecletica-1594	32	30	anti	anti	ADJ
ecletica-1594	32	31	-	-	ADJ
ecletica-1594	32	32	hypoglycemic	hypoglycemic	ADJ
ecletica-1594	32	33	,	,	PUNCT
ecletica-1594	32	34	anticancer	anticancer	NOUN
ecletica-1594	32	35	,	,	PUNCT
ecletica-1594	32	36	and	and	CCONJ
ecletica-1594	32	37	enzyme	enzyme	NOUN
ecletica-1594	32	38	inhibition	inhibition	NOUN
ecletica-1594	32	39	(	(	PUNCT
ecletica-1594	32	40	farhan	farhan	PROPN
ecletica-1594	32	41	et	et	PROPN
ecletica-1594	32	42	al	al	PROPN
ecletica-1594	32	43	.	.	PROPN
ecletica-1594	32	44	,	,	PUNCT
ecletica-1594	32	45	2018	2018	NUM
ecletica-1594	32	46	;	;	PUNCT
ecletica-1594	32	47	hu	hu	PROPN
ecletica-1594	32	48	et	et	PROPN
ecletica-1594	32	49	al	al	PROPN
ecletica-1594	32	50	.	.	PROPN
ecletica-1594	32	51	,	,	PUNCT
ecletica-1594	32	52	2008	2008	NUM
ecletica-1594	32	53	;	;	PUNCT
ecletica-1594	32	54	supuran	supuran	NOUN
ecletica-1594	32	55	,	,	PUNCT
ecletica-1594	32	56	2017	2017	NUM
ecletica-1594	32	57	;	;	PUNCT
ecletica-1594	32	58	zhao	zhao	PROPN
ecletica-1594	32	59	et	et	PROPN
ecletica-1594	32	60	al	al	PROPN
ecletica-1594	32	61	.	.	PROPN
ecletica-1594	32	62	,	,	PUNCT
ecletica-1594	32	63	2019	2019	NUM
ecletica-1594	32	64	)	)	PUNCT
ecletica-1594	32	65	.	.	PUNCT
ecletica-1594	33	1	sulfonamide	sulfonamide	NOUN
ecletica-1594	33	2	derivatives	derivative	NOUN
ecletica-1594	33	3	are	be	AUX
ecletica-1594	33	4	attractive	attractive	ADJ
ecletica-1594	33	5	due	due	ADP
ecletica-1594	33	6	to	to	ADP
ecletica-1594	33	7	their	their	PRON
ecletica-1594	33	8	diverse	diverse	ADJ
ecletica-1594	33	9	biological	biological	ADJ
ecletica-1594	33	10	targets	target	NOUN
ecletica-1594	33	11	and	and	CCONJ
ecletica-1594	33	12	practical	practical	ADJ
ecletica-1594	33	13	therapeutic	therapeutic	ADJ
ecletica-1594	33	14	ability	ability	NOUN
ecletica-1594	33	15	with	with	ADP
ecletica-1594	33	16	minimal	minimal	ADJ
ecletica-1594	33	17	side	side	NOUN
ecletica-1594	33	18	effects	effect	NOUN
ecletica-1594	33	19	(	(	PUNCT
ecletica-1594	33	20	hu	hu	PROPN
ecletica-1594	33	21	et	et	PROPN
ecletica-1594	33	22	al	al	PROPN
ecletica-1594	33	23	.	.	PROPN
ecletica-1594	33	24	,	,	PUNCT
ecletica-1594	33	25	2008	2008	NUM
ecletica-1594	33	26	;	;	PUNCT
ecletica-1594	33	27	ratchanok	ratchanok	NOUN
ecletica-1594	33	28	,	,	PUNCT
ecletica-1594	33	29	2021	2021	NUM
ecletica-1594	33	30	)	)	PUNCT
ecletica-1594	33	31	.	.	PUNCT
ecletica-1594	34	1	presently	presently	ADV
ecletica-1594	34	2	,	,	PUNCT
ecletica-1594	34	3	there	there	PRON
ecletica-1594	34	4	have	have	AUX
ecletica-1594	34	5	been	be	AUX
ecletica-1594	34	6	a	a	DET
ecletica-1594	34	7	remarkable	remarkable	ADJ
ecletica-1594	34	8	advance	advance	NOUN
ecletica-1594	34	9	in	in	ADP
ecletica-1594	34	10	the	the	DET
ecletica-1594	34	11	development	development	NOUN
ecletica-1594	34	12	of	of	ADP
ecletica-1594	34	13	new	new	ADJ
ecletica-1594	34	14	potent	potent	ADJ
ecletica-1594	34	15	antibiotics	antibiotic	NOUN
ecletica-1594	34	16	for	for	ADP
ecletica-1594	34	17	combating	combat	VERB
ecletica-1594	34	18	antimicrobial	antimicrobial	ADJ
ecletica-1594	34	19	resistance	resistance	NOUN
ecletica-1594	34	20	(	(	PUNCT
ecletica-1594	34	21	bazine	bazine	PROPN
ecletica-1594	34	22	et	et	PROPN
ecletica-1594	34	23	al	al	PROPN
ecletica-1594	34	24	.	.	PROPN
ecletica-1594	34	25	,	,	PUNCT
ecletica-1594	34	26	2020a	2020a	NUM
ecletica-1594	34	27	;	;	PUNCT
ecletica-1594	34	28	masters	master	NOUN
ecletica-1594	34	29	et	et	PROPN
ecletica-1594	34	30	al	al	PROPN
ecletica-1594	34	31	.	.	PROPN
ecletica-1594	34	32	,	,	PUNCT
ecletica-1594	34	33	2003	2003	NUM
ecletica-1594	34	34	)	)	PUNCT
ecletica-1594	34	35	;	;	PUNCT
ecletica-1594	34	36	however	however	ADV
ecletica-1594	34	37	,	,	PUNCT
ecletica-1594	34	38	the	the	DET
ecletica-1594	34	39	microorganisms	microorganism	NOUN
ecletica-1594	34	40	are	be	AUX
ecletica-1594	34	41	getting	get	VERB
ecletica-1594	34	42	resistant	resistant	ADJ
ecletica-1594	34	43	to	to	ADP
ecletica-1594	34	44	the	the	DET
ecletica-1594	34	45	existing	exist	VERB
ecletica-1594	34	46	antibiotic	antibiotic	ADJ
ecletica-1594	34	47	classes	class	NOUN
ecletica-1594	34	48	by	by	ADP
ecletica-1594	34	49	mutation	mutation	NOUN
ecletica-1594	34	50	of	of	ADP
ecletica-1594	34	51	membrane	membrane	NOUN
ecletica-1594	34	52	permeability	permeability	NOUN
ecletica-1594	34	53	and	and	CCONJ
ecletica-1594	34	54	spore	spore	ADJ
ecletica-1594	34	55	formation	formation	NOUN
ecletica-1594	34	56	to	to	ADP
ecletica-1594	34	57	the	the	DET
ecletica-1594	34	58	drugs	drug	NOUN
ecletica-1594	34	59	(	(	PUNCT
ecletica-1594	34	60	forgacs	forgac	NOUN
ecletica-1594	34	61	et	et	PROPN
ecletica-1594	34	62	al	al	PROPN
ecletica-1594	34	63	.	.	PROPN
ecletica-1594	34	64	,	,	PUNCT
ecletica-1594	34	65	2009	2009	NUM
ecletica-1594	34	66	)	)	PUNCT
ecletica-1594	34	67	thereby	thereby	ADV
ecletica-1594	34	68	adapting	adapt	VERB
ecletica-1594	34	69	themselves	themselves	PRON
ecletica-1594	34	70	to	to	PART
ecletica-1594	34	71	withstand	withstand	VERB
ecletica-1594	34	72	the	the	DET
ecletica-1594	34	73	potency	potency	NOUN
ecletica-1594	34	74	of	of	ADP
ecletica-1594	34	75	the	the	DET
ecletica-1594	34	76	drug	drug	NOUN
ecletica-1594	34	77	.	.	PUNCT
ecletica-1594	35	1	this	this	PRON
ecletica-1594	35	2	has	have	AUX
ecletica-1594	35	3	led	lead	VERB
ecletica-1594	35	4	to	to	ADP
ecletica-1594	35	5	continuous	continuous	ADJ
ecletica-1594	35	6	research	research	NOUN
ecletica-1594	35	7	on	on	ADP
ecletica-1594	35	8	drug	drug	NOUN
ecletica-1594	35	9	development	development	NOUN
ecletica-1594	35	10	and	and	CCONJ
ecletica-1594	35	11	discovery	discovery	NOUN
ecletica-1594	35	12	to	to	PART
ecletica-1594	35	13	produce	produce	VERB
ecletica-1594	35	14	new	new	ADJ
ecletica-1594	35	15	drugs	drug	NOUN
ecletica-1594	35	16	that	that	PRON
ecletica-1594	35	17	can	can	AUX
ecletica-1594	35	18	fight	fight	VERB
ecletica-1594	35	19	the	the	DET
ecletica-1594	35	20	resistance	resistance	NOUN
ecletica-1594	35	21	caused	cause	VERB
ecletica-1594	35	22	by	by	ADP
ecletica-1594	35	23	staphylococcus	staphylococcus	NOUN
ecletica-1594	35	24	aureus	aureus	NOUN
ecletica-1594	35	25	.	.	PUNCT
ecletica-1594	36	1	in	in	ADP
ecletica-1594	36	2	recent	recent	ADJ
ecletica-1594	36	3	times	time	NOUN
ecletica-1594	36	4	,	,	PUNCT
ecletica-1594	36	5	sulfamidophosphonate	sulfamidophosphonate	NOUN
ecletica-1594	36	6	,	,	PUNCT
ecletica-1594	36	7	a	a	DET
ecletica-1594	36	8	sulfonamide	sulfonamide	NOUN
ecletica-1594	36	9	and	and	CCONJ
ecletica-1594	36	10	cyclosulfamide	cyclosulfamide	NOUN
ecletica-1594	36	11	derivative	derivative	NOUN
ecletica-1594	36	12	,	,	PUNCT
ecletica-1594	36	13	have	have	AUX
ecletica-1594	36	14	been	be	AUX
ecletica-1594	36	15	a	a	DET
ecletica-1594	36	16	focus	focus	NOUN
ecletica-1594	36	17	of	of	ADP
ecletica-1594	36	18	chemical	chemical	ADJ
ecletica-1594	36	19	and	and	CCONJ
ecletica-1594	36	20	biological	biological	ADJ
ecletica-1594	36	21	researchers	researcher	NOUN
ecletica-1594	36	22	for	for	ADP
ecletica-1594	36	23	the	the	DET
ecletica-1594	36	24	development	development	NOUN
ecletica-1594	36	25	of	of	ADP
ecletica-1594	36	26	new	new	ADJ
ecletica-1594	36	27	drugs	drug	NOUN
ecletica-1594	36	28	,	,	PUNCT
ecletica-1594	36	29	due	due	ADP
ecletica-1594	36	30	to	to	ADP
ecletica-1594	36	31	its	its	PRON
ecletica-1594	36	32	wide	wide	ADJ
ecletica-1594	36	33	range	range	NOUN
ecletica-1594	36	34	of	of	ADP
ecletica-1594	36	35	biological	biological	ADJ
ecletica-1594	36	36	and	and	CCONJ
ecletica-1594	36	37	physical	physical	ADJ
ecletica-1594	36	38	properties	property	NOUN
ecletica-1594	36	39	(	(	PUNCT
ecletica-1594	36	40	krátký	krátký	PROPN
ecletica-1594	36	41	et	et	PROPN
ecletica-1594	36	42	al	al	PROPN
ecletica-1594	36	43	.	.	PROPN
ecletica-1594	36	44	,	,	PUNCT
ecletica-1594	36	45	2012	2012	NUM
ecletica-1594	36	46	;	;	PUNCT
ecletica-1594	36	47	waring	ware	VERB
ecletica-1594	36	48	et	et	PROPN
ecletica-1594	36	49	al	al	PROPN
ecletica-1594	36	50	.	.	PROPN
ecletica-1594	36	51	,	,	PUNCT
ecletica-1594	36	52	2015	2015	NUM
ecletica-1594	36	53	)	)	PUNCT
ecletica-1594	36	54	.	.	PUNCT
ecletica-1594	37	1	in	in	ADP
ecletica-1594	37	2	this	this	DET
ecletica-1594	37	3	study	study	NOUN
ecletica-1594	37	4	,	,	PUNCT
ecletica-1594	37	5	computational	computational	ADJ
ecletica-1594	37	6	methods	method	NOUN
ecletica-1594	37	7	,	,	PUNCT
ecletica-1594	37	8	including	include	VERB
ecletica-1594	37	9	molecular	molecular	ADJ
ecletica-1594	37	10	docking	docking	NOUN
ecletica-1594	37	11	and	and	CCONJ
ecletica-1594	37	12	admet	admet	PROPN
ecletica-1594	37	13	profiling	profiling	NOUN
ecletica-1594	37	14	to	to	PART
ecletica-1594	37	15	evaluate	evaluate	VERB
ecletica-1594	37	16	antibacterial	antibacterial	ADJ
ecletica-1594	37	17	activities	activity	NOUN
ecletica-1594	37	18	of	of	ADP
ecletica-1594	37	19	some	some	DET
ecletica-1594	37	20	selected	select	VERB
ecletica-1594	37	21	sulfamidophosphonate	sulfamidophosphonate	ADJ
ecletica-1594	37	22	derivatives	derivative	NOUN
ecletica-1594	37	23	based	base	VERB
ecletica-1594	37	24	on	on	ADP
ecletica-1594	37	25	the	the	DET
ecletica-1594	37	26	work	work	NOUN
ecletica-1594	37	27	of	of	ADP
ecletica-1594	37	28	bazine	bazine	PROPN
ecletica-1594	37	29	et	et	PROPN
ecletica-1594	37	30	al	al	PROPN
ecletica-1594	37	31	.	.	PROPN
ecletica-1594	37	32	(	(	PUNCT
ecletica-1594	37	33	2020b	2020b	NUM
ecletica-1594	37	34	)	)	PUNCT
ecletica-1594	37	35	.	.	PUNCT
ecletica-1594	38	1	these	these	DET
ecletica-1594	38	2	compounds	compound	NOUN
ecletica-1594	38	3	are	be	AUX
ecletica-1594	38	4	1-(1,1	1-(1,1	ADJ
ecletica-1594	38	5	-	-	PUNCT
ecletica-1594	38	6	dioxo-1λ6,2,5thiadiazolidin-2	dioxo-1λ6,2,5thiadiazolidin-2	NOUN
ecletica-1594	38	7	-	-	PUNCT
ecletica-1594	38	8	yl)(2	yl)(2	PROPN
ecletica-1594	38	9	-	-	PUNCT
ecletica-1594	38	10	oxo-1,2,3,4	oxo-1,2,3,4	ADJ
ecletica-1594	38	11	-	-	PUNCT
ecletica-1594	38	12	tetrahydroquinolin-3	tetrahydroquinolin-3	NUM
ecletica-1594	38	13	-	-	PUNCT
ecletica-1594	38	14	yl)(1,1diethoxyphosphonate	yl)(1,1diethoxyphosphonate	NOUN
ecletica-1594	38	15	(	(	PUNCT
ecletica-1594	38	16	5ad	5ad	NOUN
ecletica-1594	38	17	)	)	PUNCT
ecletica-1594	38	18	,	,	PUNCT
ecletica-1594	38	19	1,1-(3	1,1-(3	PROPN
ecletica-1594	38	20	-	-	PUNCT
ecletica-1594	38	21	methylphenylsulfonamidyl)(6	methylphenylsulfonamidyl)(6	NOUN
ecletica-1594	38	22	-	-	PUNCT
ecletica-1594	38	23	methyl-3,4	methyl-3,4	NOUN
ecletica-1594	38	24	-	-	PUNCT
ecletica-1594	38	25	dihydroquinolin-2(1h)onyl)methyl)(1,1	dihydroquinolin-2(1h)onyl)methyl)(1,1	NOUN
ecletica-1594	38	26	-	-	PUNCT
ecletica-1594	38	27	diethoxy)phosphonate	diethoxy)phosphonate	ADJ
ecletica-1594	38	28	(	(	PUNCT
ecletica-1594	38	29	nai	nai	NOUN
ecletica-1594	38	30	)	)	PUNCT
ecletica-1594	38	31	,	,	PUNCT
ecletica-1594	38	32	1,1-(3methylphenyl	1,1-(3methylphenyl	NUM
ecletica-1594	38	33	-	-	PUNCT
ecletica-1594	38	34	sulfonamidyl)(3,4	sulfonamidyl)(3,4	ADJ
ecletica-1594	38	35	-	-	PUNCT
ecletica-1594	38	36	dihydroquinolin-2(1h)onyl)methyl)(1,1	dihydroquinolin-2(1h)onyl)methyl)(1,1	NOUN
ecletica-1594	38	37	-	-	PUNCT
ecletica-1594	38	38	diethoxy)phosphonate	diethoxy)phosphonate	ADJ
ecletica-1594	38	39	(	(	PUNCT
ecletica-1594	38	40	nah	nah	INTJ
ecletica-1594	38	41	)	)	PUNCT
ecletica-1594	38	42	,	,	PUNCT
ecletica-1594	38	43	1,1-(phenylsulfonamidyl)(6	1,1-(phenylsulfonamidyl)(6	NUM
ecletica-1594	38	44	-	-	PUNCT
ecletica-1594	38	45	methyl-3,4	methyl-3,4	ADP
ecletica-1594	38	46	-	-	PUNCT
ecletica-1594	38	47	dihydroquinolin-2(1h)onyl)methyl)(1,1	dihydroquinolin-2(1h)onyl)methyl)(1,1	NOUN
ecletica-1594	38	48	-	-	PUNCT
ecletica-1594	38	49	diethoxy)phosphonate	diethoxy)phosphonate	ADJ
ecletica-1594	38	50	(	(	PUNCT
ecletica-1594	38	51	naj	naj	NOUN
ecletica-1594	38	52	)	)	PUNCT
ecletica-1594	38	53	,	,	PUNCT
ecletica-1594	38	54	1,1-(2methylphenyl	1,1-(2methylphenyl	NUM
ecletica-1594	38	55	-	-	PUNCT
ecletica-1594	38	56	sulfonamidyl)(3,4	sulfonamidyl)(3,4	ADJ
ecletica-1594	38	57	-	-	PUNCT
ecletica-1594	38	58	dihydroquinolin-2(1h)onyl)methyl)(1,1	dihydroquinolin-2(1h)onyl)methyl)(1,1	NOUN
ecletica-1594	38	59	-	-	PUNCT
ecletica-1594	38	60	diethoxy)phosphonate	diethoxy)phosphonate	PROPN
ecletica-1594	38	61	(	(	PUNCT
ecletica-1594	38	62	nak	nak	NOUN
ecletica-1594	38	63	)	)	PUNCT
ecletica-1594	38	64	,	,	PUNCT
ecletica-1594	38	65	1,1-(3methylphenyl)-sulfonamidyl)(2	1,1-(3methylphenyl)-sulfonamidyl)(2	NUM
ecletica-1594	38	66	-	-	SYM
ecletica-1594	38	67	methyl-3,4	methyl-3,4	NUM
ecletica-1594	38	68	-	-	PUNCT
ecletica-1594	38	69	dihydroquinolin2(1h)-onyl)methyl)(1,1	dihydroquinolin2(1h)-onyl)methyl)(1,1	NOUN
ecletica-1594	38	70	-	-	PUNCT
ecletica-1594	38	71	diethoxy)phosphonate	diethoxy)phosphonate	ADJ
ecletica-1594	38	72	(	(	PUNCT
ecletica-1594	38	73	nal	nal	NOUN
ecletica-1594	38	74	)	)	PUNCT
ecletica-1594	38	75	,	,	PUNCT
ecletica-1594	38	76	1,1-(3chlorophenyl)-sulfonamidyl)(2	1,1-(3chlorophenyl)-sulfonamidyl)(2	NUM
ecletica-1594	38	77	-	-	PUNCT
ecletica-1594	38	78	methyl-3,4	methyl-3,4	NUM
ecletica-1594	38	79	-	-	PUNCT
ecletica-1594	38	80	dihydroquinolin2(1h)-onyl)methyl)(1,1	dihydroquinolin2(1h)-onyl)methyl)(1,1	NOUN
ecletica-1594	38	81	-	-	PUNCT
ecletica-1594	38	82	diethoxy)phosphonate	diethoxy)phosphonate	ADJ
ecletica-1594	38	83	(	(	PUNCT
ecletica-1594	38	84	nam	nam	NOUN
ecletica-1594	38	85	)	)	PUNCT
ecletica-1594	38	86	,	,	PUNCT
ecletica-1594	38	87	and	and	CCONJ
ecletica-1594	38	88	1,1(2	1,1(2	NUM
ecletica-1594	38	89	-	-	PUNCT
ecletica-1594	38	90	hydroxylphenyl)-sulfonamidyl)(2	hydroxylphenyl)-sulfonamidyl)(2	NOUN
ecletica-1594	38	91	-	-	PUNCT
ecletica-1594	38	92	methyl-3,4	methyl-3,4	NUM
ecletica-1594	38	93	-	-	PUNCT
ecletica-1594	38	94	dihydroquinolin2(1h)-onyl)methyl)(1,1	dihydroquinolin2(1h)-onyl)methyl)(1,1	NOUN
ecletica-1594	38	95	-	-	PUNCT
ecletica-1594	38	96	diethoxy)phosphonate	diethoxy)phosphonate	ADJ
ecletica-1594	38	97	(	(	PUNCT
ecletica-1594	38	98	nan	nan	PROPN
ecletica-1594	38	99	)	)	PUNCT
ecletica-1594	38	100	.	.	PUNCT
ecletica-1594	39	1	2	2	X
ecletica-1594	39	2	.	.	X
ecletica-1594	39	3	details	detail	NOUN
ecletica-1594	39	4	of	of	ADP
ecletica-1594	39	5	research	research	NOUN
ecletica-1594	39	6	methods	method	NOUN
ecletica-1594	39	7	2.1	2.1	NUM
ecletica-1594	39	8	.	.	PUNCT
ecletica-1594	40	1	geometry	geometry	NOUN
ecletica-1594	40	2	optimization	optimization	NOUN
ecletica-1594	40	3	of	of	ADP
ecletica-1594	40	4	the	the	DET
ecletica-1594	40	5	ligands	ligand	NOUN
ecletica-1594	40	6	the	the	DET
ecletica-1594	40	7	conformer	conformer	NOUN
ecletica-1594	40	8	search	search	NOUN
ecletica-1594	40	9	was	be	AUX
ecletica-1594	40	10	carried	carry	VERB
ecletica-1594	40	11	out	out	ADP
ecletica-1594	40	12	on	on	ADP
ecletica-1594	40	13	each	each	DET
ecletica-1594	40	14	sulfamidophosphonate	sulfamidophosphonate	NOUN
ecletica-1594	40	15	using	use	VERB
ecletica-1594	40	16	the	the	DET
ecletica-1594	40	17	dft	dft	PROPN
ecletica-1594	40	18	method	method	NOUN
ecletica-1594	40	19	to	to	PART
ecletica-1594	40	20	find	find	VERB
ecletica-1594	40	21	the	the	DET
ecletica-1594	40	22	conformer	conformer	NOUN
ecletica-1594	40	23	with	with	ADP
ecletica-1594	40	24	the	the	DET
ecletica-1594	40	25	lowest	low	ADJ
ecletica-1594	40	26	energy	energy	NOUN
ecletica-1594	40	27	for	for	ADP
ecletica-1594	40	28	each	each	DET
ecletica-1594	40	29	compound	compound	NOUN
ecletica-1594	40	30	,	,	PUNCT
ecletica-1594	40	31	which	which	PRON
ecletica-1594	40	32	was	be	AUX
ecletica-1594	40	33	then	then	ADV
ecletica-1594	40	34	taken	take	VERB
ecletica-1594	40	35	as	as	ADP
ecletica-1594	40	36	the	the	DET
ecletica-1594	40	37	equilibrium	equilibrium	NOUN
ecletica-1594	40	38	geometry	geometry	NOUN
ecletica-1594	40	39	structure	structure	NOUN
ecletica-1594	40	40	of	of	ADP
ecletica-1594	40	41	the	the	DET
ecletica-1594	40	42	compound	compound	NOUN
ecletica-1594	40	43	.	.	PUNCT
ecletica-1594	41	1	the	the	DET
ecletica-1594	41	2	equilibrium	equilibrium	NOUN
ecletica-1594	41	3	optimization	optimization	NOUN
ecletica-1594	41	4	was	be	AUX
ecletica-1594	41	5	performed	perform	VERB
ecletica-1594	41	6	on	on	ADP
ecletica-1594	41	7	the	the	DET
ecletica-1594	41	8	ligands	ligand	NOUN
ecletica-1594	41	9	(	(	PUNCT
ecletica-1594	41	10	fig	fig	NOUN
ecletica-1594	41	11	.	.	NOUN
ecletica-1594	41	12	1	1	NUM
ecletica-1594	41	13	)	)	PUNCT
ecletica-1594	41	14	with	with	ADP
ecletica-1594	41	15	dft	dft	PROPN
ecletica-1594	41	16	in	in	ADP
ecletica-1594	41	17	correlation	correlation	NOUN
ecletica-1594	41	18	with	with	ADP
ecletica-1594	41	19	becke	becke	NOUN
ecletica-1594	41	20	’s	’s	PART
ecletica-1594	41	21	three	three	NUM
ecletica-1594	41	22	-	-	PUNCT
ecletica-1594	41	23	parameter	parameter	NOUN
ecletica-1594	41	24	hybrid	hybrid	ADJ
ecletica-1594	41	25	functional	functional	ADJ
ecletica-1594	41	26	with	with	ADP
ecletica-1594	41	27	a	a	DET
ecletica-1594	41	28	correlation	correlation	NOUN
ecletica-1594	41	29	of	of	ADP
ecletica-1594	41	30	lee	lee	PROPN
ecletica-1594	41	31	,	,	PUNCT
ecletica-1594	41	32	yang	yang	PROPN
ecletica-1594	41	33	and	and	CCONJ
ecletica-1594	41	34	parr	parr	X
ecletica-1594	41	35	(	(	PUNCT
ecletica-1594	41	36	b3lyp	b3lyp	NUM
ecletica-1594	41	37	)	)	PUNCT
ecletica-1594	41	38	(	(	PUNCT
ecletica-1594	41	39	becke	becke	NOUN
ecletica-1594	41	40	,	,	PUNCT
ecletica-1594	41	41	1993	1993	NUM
ecletica-1594	41	42	;	;	PUNCT
ecletica-1594	41	43	hehre	hehre	PROPN
ecletica-1594	41	44	et	et	PROPN
ecletica-1594	41	45	al	al	PROPN
ecletica-1594	41	46	.	.	PROPN
ecletica-1594	41	47	,	,	PUNCT
ecletica-1594	41	48	1988	1988	NUM
ecletica-1594	41	49	;	;	PUNCT
ecletica-1594	41	50	parr	parr	PROPN
ecletica-1594	41	51	et	et	PROPN
ecletica-1594	41	52	al	al	PROPN
ecletica-1594	41	53	.	.	PROPN
ecletica-1594	41	54	,	,	PUNCT
ecletica-1594	41	55	1999	1999	NUM
ecletica-1594	41	56	;	;	PUNCT
ecletica-1594	42	1	yang	yang	PROPN
ecletica-1594	42	2	et	et	PROPN
ecletica-1594	42	3	al	al	PROPN
ecletica-1594	42	4	.	.	PROPN
ecletica-1594	42	5	,	,	PUNCT
ecletica-1594	42	6	2005	2005	NUM
ecletica-1594	42	7	;	;	PUNCT
ecletica-1594	42	8	lee	lee	PROPN
ecletica-1594	42	9	et	et	PROPN
ecletica-1594	42	10	al	al	PROPN
ecletica-1594	42	11	.	.	PROPN
ecletica-1594	42	12	,	,	PUNCT
ecletica-1594	42	13	1988	1988	NUM
ecletica-1594	42	14	)	)	PUNCT
ecletica-1594	42	15	with	with	ADP
ecletica-1594	42	16	6	6	NUM
ecletica-1594	42	17	-	-	SYM
ecletica-1594	42	18	31g(d	31g(d	NUM
ecletica-1594	42	19	,	,	PUNCT
ecletica-1594	42	20	p	p	NOUN
ecletica-1594	42	21	)	)	PUNCT
ecletica-1594	42	22	basis	basis	NOUN
ecletica-1594	42	23	set	set	NOUN
ecletica-1594	42	24	.	.	PUNCT
ecletica-1594	43	1	quantum	quantum	ADJ
ecletica-1594	43	2	chemical	chemical	NOUN
ecletica-1594	43	3	reactivity	reactivity	NOUN
ecletica-1594	43	4	descriptors	descriptor	NOUN
ecletica-1594	43	5	of	of	ADP
ecletica-1594	43	6	the	the	DET
ecletica-1594	43	7	sulfamidophosphonates	sulfamidophosphonate	NOUN
ecletica-1594	43	8	such	such	ADJ
ecletica-1594	43	9	as	as	ADP
ecletica-1594	43	10	frontier	frontier	NOUN
ecletica-1594	43	11	orbital	orbital	ADJ
ecletica-1594	43	12	energies	energy	NOUN
ecletica-1594	43	13	,	,	PUNCT
ecletica-1594	43	14	which	which	PRON
ecletica-1594	43	15	are	be	AUX
ecletica-1594	43	16	the	the	DET
ecletica-1594	43	17	highest	high	ADJ
ecletica-1594	43	18	occupied	occupy	VERB
ecletica-1594	43	19	molecular	molecular	ADJ
ecletica-1594	43	20	orbital	orbital	ADJ
ecletica-1594	43	21	energy	energy	NOUN
ecletica-1594	43	22	(	(	PUNCT
ecletica-1594	43	23	ehomo	ehomo	ADJ
ecletica-1594	43	24	)	)	PUNCT
ecletica-1594	43	25	,	,	PUNCT
ecletica-1594	43	26	the	the	DET
ecletica-1594	43	27	lowest	lowest	ADV
ecletica-1594	43	28	unoccupied	unoccupied	ADJ
ecletica-1594	43	29	molecular	molecular	ADJ
ecletica-1594	43	30	orbital	orbital	ADJ
ecletica-1594	43	31	energy	energy	NOUN
ecletica-1594	43	32	(	(	PUNCT
ecletica-1594	43	33	elumo	elumo	ADJ
ecletica-1594	43	34	)	)	PUNCT
ecletica-1594	43	35	and	and	CCONJ
ecletica-1594	43	36	band	band	NOUN
ecletica-1594	43	37	energy	energy	NOUN
ecletica-1594	43	38	gap	gap	NOUN
ecletica-1594	43	39	(	(	PUNCT
ecletica-1594	43	40	e(homo	e(homo	ADJ
ecletica-1594	43	41	–	–	PUNCT
ecletica-1594	43	42	lumo	lumo	NOUN
ecletica-1594	43	43	)	)	PUNCT
ecletica-1594	43	44	;	;	PUNCT
ecletica-1594	43	45	chemical	chemical	NOUN
ecletica-1594	43	46	hardness	hardness	NOUN
ecletica-1594	43	47	(	(	PUNCT
ecletica-1594	43	48	η	η	PROPN
ecletica-1594	43	49	=	=	PROPN
ecletica-1594	43	50	ehomo−elumo	ehomo−elumo	PRON
ecletica-1594	43	51	2	2	NUM
ecletica-1594	43	52	)	)	PUNCT
ecletica-1594	43	53	;	;	PUNCT
ecletica-1594	43	54	chemical	chemical	NOUN
ecletica-1594	43	55	softness	softness	NOUN
ecletica-1594	43	56	(	(	PUNCT
ecletica-1594	43	57	σ	σ	NOUN
ecletica-1594	43	58	=	=	SYM
ecletica-1594	43	59	1	1	NUM
ecletica-1594	43	60	2𝜂	2𝜂	NOUN
ecletica-1594	43	61	)	)	PUNCT
ecletica-1594	43	62	;	;	PUNCT
ecletica-1594	43	63	chemical	chemical	NOUN
ecletica-1594	43	64	potential	potential	NOUN
ecletica-1594	43	65	(	(	PUNCT
ecletica-1594	43	66	μ	μ	NOUN
ecletica-1594	43	67	=	=	PUNCT
ecletica-1594	43	68	(	(	PUNCT
ecletica-1594	43	69	𝐸𝐻𝑂𝑀𝑂+	𝐸𝐻𝑂𝑀𝑂+	ADJ
ecletica-1594	43	70	𝐸𝐿𝑈𝑀𝑂	𝐸𝐿𝑈𝑀𝑂	ADJ
ecletica-1594	43	71	2	2	NUM
ecletica-1594	43	72	)	)	PUNCT
ecletica-1594	43	73	;	;	PUNCT
ecletica-1594	43	74	global	global	ADJ
ecletica-1594	43	75	electrophilicity	electrophilicity	NOUN
ecletica-1594	43	76	(	(	PUNCT
ecletica-1594	43	77	ω	ω	NUM
ecletica-1594	43	78	=	=	NOUN
ecletica-1594	43	79	μ2	μ2	PROPN
ecletica-1594	43	80	2η	2η	PROPN
ecletica-1594	43	81	=	=	SYM
ecletica-1594	43	82	(	(	PUNCT
ecletica-1594	43	83	ip+ea)2	ip+ea)2	PROPN
ecletica-1594	43	84	4(ip−ea	4(ip−ea	NUM
ecletica-1594	43	85	)	)	PUNCT
ecletica-1594	43	86	)	)	PUNCT
ecletica-1594	43	87	;	;	PUNCT
ecletica-1594	43	88	electron	electron	NOUN
ecletica-1594	43	89	donating	donate	VERB
ecletica-1594	43	90	power	power	NOUN
ecletica-1594	43	91	(	(	PUNCT
ecletica-1594	43	92	ω	ω	NOUN
ecletica-1594	43	93	–	–	PUNCT
ecletica-1594	43	94	=	=	SYM
ecletica-1594	43	95	(	(	PUNCT
ecletica-1594	43	96	3𝐼𝑃+𝐸𝐴	3𝐼𝑃+𝐸𝐴	NUM
ecletica-1594	43	97	)	)	PUNCT
ecletica-1594	43	98	2	2	NUM
ecletica-1594	43	99	16(𝐼𝑃−𝐸𝐴	16(𝐼𝑃−𝐸𝐴	NUM
ecletica-1594	43	100	)	)	PUNCT
ecletica-1594	43	101	)	)	PUNCT
ecletica-1594	43	102	and	and	CCONJ
ecletica-1594	43	103	electron	electron	NOUN
ecletica-1594	43	104	accepting	accept	VERB
ecletica-1594	43	105	power	power	NOUN
ecletica-1594	43	106	(	(	PUNCT
ecletica-1594	43	107	ω+	ω+	X
ecletica-1594	43	108	=	=	SYM
ecletica-1594	43	109	(	(	PUNCT
ecletica-1594	43	110	𝐼𝑃+3𝐸𝐴	𝐼𝑃+3𝐸𝐴	PROPN
ecletica-1594	43	111	)	)	PUNCT
ecletica-1594	43	112	2	2	NUM
ecletica-1594	43	113	16(𝐼𝑃−𝐸𝐴	16(𝐼𝑃−𝐸𝐴	NUM
ecletica-1594	43	114	)	)	PUNCT
ecletica-1594	43	115	)	)	PUNCT
ecletica-1594	43	116	were	be	AUX
ecletica-1594	43	117	estimated	estimate	VERB
ecletica-1594	43	118	form	form	NOUN
ecletica-1594	43	119	the	the	DET
ecletica-1594	43	120	optimized	optimize	VERB
ecletica-1594	43	121	structures	structure	NOUN
ecletica-1594	43	122	(	(	PUNCT
ecletica-1594	43	123	flores	flores	PROPN
ecletica-1594	43	124	-	-	PUNCT
ecletica-1594	43	125	holguín	holguín	PROPN
ecletica-1594	43	126	et	et	PROPN
ecletica-1594	43	127	al	al	PROPN
ecletica-1594	43	128	.	.	PROPN
ecletica-1594	43	129	,	,	PUNCT
ecletica-1594	43	130	2019	2019	NUM
ecletica-1594	43	131	;	;	PUNCT
ecletica-1594	43	132	manzanilla	manzanilla	NOUN
ecletica-1594	43	133	and	and	CCONJ
ecletica-1594	43	134	robles	roble	NOUN
ecletica-1594	43	135	,	,	PUNCT
ecletica-1594	43	136	2020	2020	NUM
ecletica-1594	43	137	;	;	PUNCT
ecletica-1594	43	138	ramírez	ramírez	NOUN
ecletica-1594	43	139	-	-	PUNCT
ecletica-1594	43	140	martínez	martínez	NOUN
ecletica-1594	43	141	et	et	NOUN
ecletica-1594	43	142	at	at	ADP
ecletica-1594	43	143	.	.	PROPN
ecletica-1594	43	144	,	,	PUNCT
ecletica-1594	43	145	2023	2023	NUM
ecletica-1594	43	146	)	)	PUNCT
ecletica-1594	43	147	.	.	PUNCT
ecletica-1594	44	1	2.2	2.2	NUM
ecletica-1594	44	2	.	.	PUNCT
ecletica-1594	44	3	molecular	molecular	ADJ
ecletica-1594	44	4	docking	docking	NOUN
ecletica-1594	44	5	procedures	procedure	NOUN
ecletica-1594	44	6	the	the	DET
ecletica-1594	44	7	optimized	optimize	VERB
ecletica-1594	44	8	ligands	ligand	NOUN
ecletica-1594	44	9	were	be	AUX
ecletica-1594	44	10	docked	dock	VERB
ecletica-1594	44	11	into	into	ADP
ecletica-1594	44	12	the	the	DET
ecletica-1594	44	13	receptors	receptor	NOUN
ecletica-1594	44	14	by	by	ADP
ecletica-1594	44	15	using	use	VERB
ecletica-1594	44	16	autodock	autodock	NOUN
ecletica-1594	44	17	tool	tool	NOUN
ecletica-1594	44	18	1.5.6	1.5.6	NUM
ecletica-1594	44	19	.	.	PROPN
ecletica-1594	44	20	,	,	PUNCT
ecletica-1594	44	21	autodock	autodock	PROPN
ecletica-1594	44	22	vina	vina	PROPN
ecletica-1594	44	23	1.1.2	1.1.2	NUM
ecletica-1594	44	24	,	,	PUNCT
ecletica-1594	44	25	edupymol	edupymol	PROPN
ecletica-1594	44	26	version	version	NOUN
ecletica-1594	44	27	1.7.4.4	1.7.4.4	NUM
ecletica-1594	44	28	and	and	CCONJ
ecletica-1594	44	29	discovery	discovery	PROPN
ecletica-1594	44	30	studio	studio	NOUN
ecletica-1594	44	31	.	.	PUNCT
ecletica-1594	45	1	the	the	DET
ecletica-1594	45	2	receptors	receptor	NOUN
ecletica-1594	45	3	/	/	SYM
ecletica-1594	45	4	proteins	protein	NOUN
ecletica-1594	45	5	were	be	AUX
ecletica-1594	45	6	cleaned	clean	VERB
ecletica-1594	45	7	up	up	ADP
ecletica-1594	45	8	and	and	CCONJ
ecletica-1594	45	9	repaired	repair	VERB
ecletica-1594	45	10	with	with	ADP
ecletica-1594	45	11	discovery	discovery	NOUN
ecletica-1594	45	12	studio	studio	NOUN
ecletica-1594	45	13	software	software	NOUN
ecletica-1594	45	14	,	,	PUNCT
ecletica-1594	45	15	and	and	CCONJ
ecletica-1594	45	16	edupymol	edupymol	PROPN
ecletica-1594	45	17	was	be	AUX
ecletica-1594	45	18	used	use	VERB
ecletica-1594	45	19	to	to	PART
ecletica-1594	45	20	visualize	visualize	VERB
ecletica-1594	45	21	the	the	DET
ecletica-1594	45	22	docking	docking	NOUN
ecletica-1594	45	23	results	result	NOUN
ecletica-1594	45	24	as	as	SCONJ
ecletica-1594	45	25	described	describe	VERB
ecletica-1594	45	26	(	(	PUNCT
ecletica-1594	45	27	adegbola	adegbola	PROPN
ecletica-1594	45	28	et	et	PROPN
ecletica-1594	45	29	al	al	PROPN
ecletica-1594	45	30	.	.	PROPN
ecletica-1594	45	31	,	,	PUNCT
ecletica-1594	45	32	2021a	2021a	NUM
ecletica-1594	45	33	;	;	PUNCT
ecletica-1594	45	34	adepoju	adepoju	PROPN
ecletica-1594	45	35	et	et	PROPN
ecletica-1594	45	36	al	al	PROPN
ecletica-1594	45	37	.	.	PROPN
ecletica-1594	45	38	,	,	PUNCT
ecletica-1594	45	39	2022	2022	NUM
ecletica-1594	45	40	;	;	PUNCT
ecletica-1594	45	41	oyebamiji	oyebamiji	NOUN
ecletica-1594	45	42	et	et	PROPN
ecletica-1594	45	43	al	al	PROPN
ecletica-1594	45	44	.	.	PROPN
ecletica-1594	45	45	,	,	PUNCT
ecletica-1594	45	46	2021	2021	NUM
ecletica-1594	45	47	)	)	PUNCT
ecletica-1594	45	48	.	.	PUNCT
ecletica-1594	46	1	the	the	DET
ecletica-1594	46	2	binding	bind	VERB
ecletica-1594	46	3	pocket	pocket	NOUN
ecletica-1594	46	4	of	of	ADP
ecletica-1594	46	5	the	the	DET
ecletica-1594	46	6	protein	protein	NOUN
ecletica-1594	46	7	,	,	PUNCT
ecletica-1594	46	8	as	as	SCONJ
ecletica-1594	46	9	determined	determine	VERB
ecletica-1594	46	10	in	in	ADP
ecletica-1594	46	11	the	the	DET
ecletica-1594	46	12	3d	3d	NOUN
ecletica-1594	46	13	structure	structure	NOUN
ecletica-1594	46	14	using	use	VERB
ecletica-1594	46	15	discovery	discovery	NOUN
ecletica-1594	46	16	studio	studio	NOUN
ecletica-1594	46	17	and	and	CCONJ
ecletica-1594	46	18	the	the	DET
ecletica-1594	46	19	autodock	autodock	NOUN
ecletica-1594	46	20	tool	tool	NOUN
ecletica-1594	46	21	,	,	PUNCT
ecletica-1594	46	22	was	be	AUX
ecletica-1594	46	23	used	use	VERB
ecletica-1594	46	24	to	to	PART
ecletica-1594	46	25	prepare	prepare	VERB
ecletica-1594	46	26	the	the	DET
ecletica-1594	46	27	protein	protein	NOUN
ecletica-1594	46	28	.	.	PUNCT
ecletica-1594	47	1	polar	polar	ADJ
ecletica-1594	47	2	hydrogens	hydrogen	NOUN
ecletica-1594	47	3	were	be	AUX
ecletica-1594	47	4	added	add	VERB
ecletica-1594	47	5	to	to	ADP
ecletica-1594	47	6	the	the	DET
ecletica-1594	47	7	protein	protein	NOUN
ecletica-1594	47	8	,	,	PUNCT
ecletica-1594	47	9	followed	follow	VERB
ecletica-1594	47	10	by	by	ADP
ecletica-1594	47	11	kolleman	kolleman	ADJ
ecletica-1594	47	12	charges	charge	NOUN
ecletica-1594	47	13	,	,	PUNCT
ecletica-1594	47	14	before	before	ADP
ecletica-1594	47	15	setting	set	VERB
ecletica-1594	47	16	the	the	DET
ecletica-1594	47	17	grid	grid	NOUN
ecletica-1594	47	18	box	box	NOUN
ecletica-1594	47	19	.	.	PUNCT
ecletica-1594	48	1	using	use	VERB
ecletica-1594	48	2	auto	auto	NOUN
ecletica-1594	48	3	grid	grid	NOUN
ecletica-1594	48	4	,	,	PUNCT
ecletica-1594	48	5	the	the	DET
ecletica-1594	48	6	grid	grid	NOUN
ecletica-1594	48	7	box	box	PROPN
ecletica-1594	48	8	center	center	NOUN
ecletica-1594	48	9	(	(	PUNCT
ecletica-1594	48	10	x	x	SYM
ecletica-1594	48	11	=	=	PUNCT
ecletica-1594	48	12	–	–	PUNCT
ecletica-1594	48	13	5.252	5.252	NUM
ecletica-1594	48	14	,	,	PUNCT
ecletica-1594	48	15	y	y	PROPN
ecletica-1594	48	16	=	=	PROPN
ecletica-1594	48	17	9.613	9.613	NUM
ecletica-1594	48	18	,	,	PUNCT
ecletica-1594	48	19	z	z	PROPN
ecletica-1594	48	20	=	=	SYM
ecletica-1594	48	21	36.518	36.518	NUM
ecletica-1594	48	22	)	)	PUNCT
ecletica-1594	48	23	and	and	CCONJ
ecletica-1594	48	24	size	size	NOUN
ecletica-1594	48	25	(	(	PUNCT
ecletica-1594	48	26	x	x	SYM
ecletica-1594	48	27	=	=	SYM
ecletica-1594	48	28	58	58	NUM
ecletica-1594	48	29	,	,	PUNCT
ecletica-1594	48	30	y	y	PROPN
ecletica-1594	48	31	=	=	SYM
ecletica-1594	48	32	52	52	NUM
ecletica-1594	48	33	,	,	PUNCT
ecletica-1594	48	34	z	z	NOUN
ecletica-1594	48	35	=	=	SYM
ecletica-1594	48	36	66	66	NUM
ecletica-1594	48	37	)	)	PUNCT
ecletica-1594	48	38	for	for	ADP
ecletica-1594	48	39	blai	blai	NOUN
ecletica-1594	48	40	repressor	repressor	NOUN
ecletica-1594	48	41	in	in	ADP
ecletica-1594	48	42	complex	complex	NOUN
ecletica-1594	48	43	with	with	ADP
ecletica-1594	48	44	dna	dna	PROPN
ecletica-1594	48	45	(	(	PUNCT
ecletica-1594	48	46	pdb	pdb	PROPN
ecletica-1594	48	47	i	i	PROPN
ecletica-1594	48	48	d	d	PROPN
ecletica-1594	48	49	:	:	PUNCT
ecletica-1594	48	50	1xsd	1xsd	NUM
ecletica-1594	48	51	)	)	PUNCT
ecletica-1594	48	52	,	,	PUNCT
ecletica-1594	48	53	and	and	CCONJ
ecletica-1594	48	54	(	(	PUNCT
ecletica-1594	48	55	center	center	NOUN
ecletica-1594	48	56	:	:	PUNCT
ecletica-1594	48	57	x	x	SYM
ecletica-1594	48	58	=	=	SYM
ecletica-1594	48	59	0.043	0.043	NUM
ecletica-1594	48	60	,	,	PUNCT
ecletica-1594	48	61	y	y	PROPN
ecletica-1594	48	62	=	=	PROPN
ecletica-1594	48	63	2.734	2.734	NUM
ecletica-1594	48	64	,	,	PUNCT
ecletica-1594	48	65	z	z	NOUN
ecletica-1594	48	66	=	=	SYM
ecletica-1594	48	67	85.68	85.68	NUM
ecletica-1594	48	68	)	)	PUNCT
ecletica-1594	48	69	and	and	CCONJ
ecletica-1594	48	70	(	(	PUNCT
ecletica-1594	48	71	size	size	NOUN
ecletica-1594	48	72	:	:	PUNCT
ecletica-1594	48	73	x	x	SYM
ecletica-1594	48	74	=	=	SYM
ecletica-1594	48	75	48	48	NUM
ecletica-1594	48	76	,	,	PUNCT
ecletica-1594	48	77	y	y	PROPN
ecletica-1594	48	78	=	=	SYM
ecletica-1594	48	79	40	40	NUM
ecletica-1594	48	80	,	,	PUNCT
ecletica-1594	48	81	z	z	NOUN
ecletica-1594	48	82	=	=	NUM
ecletica-1594	48	83	40	40	NUM
ecletica-1594	48	84	)	)	PUNCT
ecletica-1594	48	85	for	for	ADP
ecletica-1594	48	86	4wk3	4wk3	NUM
ecletica-1594	48	87	receptor	receptor	NOUN
ecletica-1594	48	88	were	be	AUX
ecletica-1594	48	89	set	set	VERB
ecletica-1594	48	90	.	.	PUNCT
ecletica-1594	49	1	the	the	DET
ecletica-1594	49	2	receptor	receptor	NOUN
ecletica-1594	49	3	and	and	CCONJ
ecletica-1594	49	4	ligand	ligand	NOUN
ecletica-1594	49	5	were	be	AUX
ecletica-1594	49	6	then	then	ADV
ecletica-1594	49	7	saved	save	VERB
ecletica-1594	49	8	as	as	ADP
ecletica-1594	49	9	pdbqt	pdbqt	ADJ
ecletica-1594	49	10	files	file	NOUN
ecletica-1594	49	11	.	.	PUNCT
ecletica-1594	50	1	the	the	DET
ecletica-1594	50	2	docking	docking	NOUN
ecletica-1594	50	3	simulations	simulation	NOUN
ecletica-1594	50	4	were	be	AUX
ecletica-1594	50	5	then	then	ADV
ecletica-1594	50	6	performed	perform	VERB
ecletica-1594	50	7	using	use	VERB
ecletica-1594	50	8	autodock	autodock	PROPN
ecletica-1594	50	9	vina	vina	NOUN
ecletica-1594	50	10	(	(	PUNCT
ecletica-1594	50	11	trott	trott	PROPN
ecletica-1594	50	12	et	et	PROPN
ecletica-1594	50	13	al	al	PROPN
ecletica-1594	50	14	.	.	PROPN
ecletica-1594	50	15	,	,	PUNCT
ecletica-1594	50	16	2010	2010	NUM
ecletica-1594	50	17	)	)	PUNCT
ecletica-1594	50	18	for	for	ADP
ecletica-1594	50	19	the	the	DET
ecletica-1594	50	20	calculations	calculation	NOUN
ecletica-1594	50	21	of	of	ADP
ecletica-1594	50	22	binding	bind	VERB
ecletica-1594	50	23	affinity	affinity	NOUN
ecletica-1594	50	24	,	,	PUNCT
ecletica-1594	50	25	as	as	ADV
ecletica-1594	50	26	well	well	ADV
ecletica-1594	50	27	as	as	ADP
ecletica-1594	50	28	studying	study	VERB
ecletica-1594	50	29	non	non	ADJ
ecletica-1594	50	30	-	-	ADJ
ecletica-1594	50	31	bonding	bonding	ADJ
ecletica-1594	50	32	interactions	interaction	NOUN
ecletica-1594	50	33	(	(	PUNCT
ecletica-1594	50	34	hydrophobic	hydrophobic	NOUN
ecletica-1594	50	35	interactions	interaction	NOUN
ecletica-1594	50	36	)	)	PUNCT
ecletica-1594	50	37	and	and	CCONJ
ecletica-1594	50	38	hydrogen	hydrogen	NOUN
ecletica-1594	50	39	bonding	bonding	NOUN
ecletica-1594	50	40	between	between	ADP
ecletica-1594	50	41	the	the	DET
ecletica-1594	50	42	ligand	ligand	NOUN
ecletica-1594	50	43	and	and	CCONJ
ecletica-1594	50	44	proteins	protein	NOUN
ecletica-1594	50	45	,	,	PUNCT
ecletica-1594	50	46	which	which	PRON
ecletica-1594	50	47	were	be	AUX
ecletica-1594	50	48	visualized	visualize	VERB
ecletica-1594	50	49	using	use	VERB
ecletica-1594	50	50	discovery	discovery	NOUN
ecletica-1594	50	51	studio	studio	NOUN
ecletica-1594	50	52	2019	2019	NUM
ecletica-1594	50	53	.	.	PUNCT
ecletica-1594	51	1	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	X
ecletica-1594	51	2	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	X
ecletica-1594	51	3	original	original	ADJ
ecletica-1594	51	4	article	article	NOUN
ecletica-1594	51	5	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	X
ecletica-1594	51	6	issn	issn	VERB
ecletica-1594	51	7	1678	1678	NUM
ecletica-1594	51	8	-	-	SYM
ecletica-1594	51	9	4618	4618	NUM
ecletica-1594	51	10	page	page	NOUN
ecletica-1594	51	11	3/14	3/14	NUM
ecletica-1594	51	12	nah	nah	PRON
ecletica-1594	51	13	nai	nai	PROPN
ecletica-1594	51	14	naj	naj	PROPN
ecletica-1594	51	15	nam	nam	PROPN
ecletica-1594	51	16	nak	nak	PROPN
ecletica-1594	51	17	nal	nal	PROPN
ecletica-1594	51	18	nan	nan	PROPN
ecletica-1594	51	19	5ad	5ad	PROPN
ecletica-1594	51	20	figure	figure	NOUN
ecletica-1594	51	21	1	1	NUM
ecletica-1594	51	22	.	.	PUNCT
ecletica-1594	51	23	optimized	optimize	VERB
ecletica-1594	51	24	structures	structure	NOUN
ecletica-1594	51	25	of	of	ADP
ecletica-1594	51	26	studied	study	VERB
ecletica-1594	51	27	sulfamidophosphonates	sulfamidophosphonate	NOUN
ecletica-1594	51	28	.	.	PUNCT
ecletica-1594	52	1	source	source	NOUN
ecletica-1594	52	2	:	:	PUNCT
ecletica-1594	52	3	elaborated	elaborate	VERB
ecletica-1594	52	4	by	by	ADP
ecletica-1594	52	5	the	the	DET
ecletica-1594	52	6	authors	author	NOUN
ecletica-1594	52	7	.	.	PUNCT
ecletica-1594	53	1	2.3	2.3	NUM
ecletica-1594	53	2	.	.	PUNCT
ecletica-1594	53	3	adme	adme	ADJ
ecletica-1594	53	4	/	/	SYM
ecletica-1594	53	5	pharmacokinetic	pharmacokinetic	ADJ
ecletica-1594	53	6	predictions	prediction	NOUN
ecletica-1594	53	7	the	the	DET
ecletica-1594	53	8	smiles	smile	NOUN
ecletica-1594	53	9	of	of	ADP
ecletica-1594	53	10	optimized	optimize	VERB
ecletica-1594	53	11	structures	structure	NOUN
ecletica-1594	53	12	of	of	ADP
ecletica-1594	53	13	the	the	DET
ecletica-1594	53	14	studied	study	VERB
ecletica-1594	53	15	ligands	ligand	NOUN
ecletica-1594	53	16	were	be	AUX
ecletica-1594	53	17	used	use	VERB
ecletica-1594	53	18	for	for	ADP
ecletica-1594	53	19	physicochemical	physicochemical	ADJ
ecletica-1594	53	20	and	and	CCONJ
ecletica-1594	53	21	admet	admet	PROPN
ecletica-1594	53	22	profiles	profile	NOUN
ecletica-1594	53	23	to	to	PART
ecletica-1594	53	24	assess	assess	VERB
ecletica-1594	53	25	the	the	DET
ecletica-1594	53	26	qualitative	qualitative	ADJ
ecletica-1594	53	27	pharmacokinetics	pharmacokinetic	NOUN
ecletica-1594	53	28	properties	property	NOUN
ecletica-1594	53	29	via	via	ADP
ecletica-1594	53	30	;	;	PUNCT
ecletica-1594	53	31	absorption	absorption	NOUN
ecletica-1594	53	32	,	,	PUNCT
ecletica-1594	53	33	distribution	distribution	NOUN
ecletica-1594	53	34	,	,	PUNCT
ecletica-1594	53	35	metabolism	metabolism	NOUN
ecletica-1594	53	36	,	,	PUNCT
ecletica-1594	53	37	excretion	excretion	NOUN
ecletica-1594	53	38	and	and	CCONJ
ecletica-1594	53	39	toxicity	toxicity	NOUN
ecletica-1594	53	40	by	by	ADP
ecletica-1594	53	41	using	use	VERB
ecletica-1594	53	42	admet	admet	PROPN
ecletica-1594	53	43	predictor	predictor	NOUN
ecletica-1594	53	44	(	(	PUNCT
ecletica-1594	53	45	http://biosig.unimelb.edu.au/pkcsm/prediction	http://biosig.unimelb.edu.au/pkcsm/prediction	NOUN
ecletica-1594	53	46	)	)	PUNCT
ecletica-1594	53	47	.	.	PUNCT
ecletica-1594	54	1	these	these	DET
ecletica-1594	54	2	early	early	ADJ
ecletica-1594	54	3	assessments	assessment	NOUN
ecletica-1594	54	4	of	of	ADP
ecletica-1594	54	5	pharmacokinetic	pharmacokinetic	ADJ
ecletica-1594	54	6	and	and	CCONJ
ecletica-1594	54	7	toxic	toxic	ADJ
ecletica-1594	54	8	properties	property	NOUN
ecletica-1594	54	9	are	be	AUX
ecletica-1594	54	10	essential	essential	ADJ
ecletica-1594	54	11	step	step	NOUN
ecletica-1594	54	12	in	in	ADP
ecletica-1594	54	13	drug	drug	NOUN
ecletica-1594	54	14	discovery	discovery	NOUN
ecletica-1594	54	15	,	,	PUNCT
ecletica-1594	54	16	although	although	SCONJ
ecletica-1594	54	17	the	the	DET
ecletica-1594	54	18	process	process	NOUN
ecletica-1594	54	19	of	of	ADP
ecletica-1594	54	20	drug	drug	NOUN
ecletica-1594	54	21	discovery	discovery	NOUN
ecletica-1594	54	22	and	and	CCONJ
ecletica-1594	54	23	development	development	NOUN
ecletica-1594	54	24	is	be	AUX
ecletica-1594	54	25	a	a	DET
ecletica-1594	54	26	very	very	ADV
ecletica-1594	54	27	complex	complex	ADJ
ecletica-1594	54	28	,	,	PUNCT
ecletica-1594	54	29	lengthy	lengthy	ADJ
ecletica-1594	54	30	and	and	CCONJ
ecletica-1594	54	31	costintensive	costintensive	ADJ
ecletica-1594	54	32	;	;	PUNCT
ecletica-1594	54	33	drug	drug	NOUN
ecletica-1594	54	34	development	development	NOUN
ecletica-1594	54	35	failures	failure	NOUN
ecletica-1594	54	36	have	have	AUX
ecletica-1594	54	37	been	be	AUX
ecletica-1594	54	38	attributed	attribute	VERB
ecletica-1594	54	39	to	to	ADP
ecletica-1594	54	40	poor	poor	ADJ
ecletica-1594	54	41	pharmacokinetics	pharmacokinetic	NOUN
ecletica-1594	54	42	and	and	CCONJ
ecletica-1594	54	43	bioavailability	bioavailability	NOUN
ecletica-1594	54	44	(	(	PUNCT
ecletica-1594	54	45	adegbola	adegbola	PROPN
ecletica-1594	54	46	et	et	PROPN
ecletica-1594	54	47	al	al	PROPN
ecletica-1594	54	48	.	.	PROPN
ecletica-1594	54	49	,	,	PUNCT
ecletica-1594	54	50	2021b	2021b	NUM
ecletica-1594	54	51	;	;	PUNCT
ecletica-1594	54	52	daina	daina	PROPN
ecletica-1594	54	53	and	and	CCONJ
ecletica-1594	54	54	zoete	zoete	NOUN
ecletica-1594	54	55	,	,	PUNCT
ecletica-1594	54	56	2016	2016	NUM
ecletica-1594	54	57	)	)	PUNCT
ecletica-1594	54	58	.	.	PUNCT
ecletica-1594	55	1	therefore	therefore	ADV
ecletica-1594	55	2	,	,	PUNCT
ecletica-1594	55	3	admet	admet	PROPN
ecletica-1594	55	4	properties	property	NOUN
ecletica-1594	55	5	play	play	VERB
ecletica-1594	55	6	a	a	DET
ecletica-1594	55	7	crucial	crucial	ADJ
ecletica-1594	55	8	role	role	NOUN
ecletica-1594	55	9	in	in	ADP
ecletica-1594	55	10	every	every	DET
ecletica-1594	55	11	stage	stage	NOUN
ecletica-1594	55	12	of	of	ADP
ecletica-1594	55	13	drug	drug	NOUN
ecletica-1594	55	14	discovery	discovery	NOUN
ecletica-1594	55	15	and	and	CCONJ
ecletica-1594	55	16	development	development	NOUN
ecletica-1594	55	17	,	,	PUNCT
ecletica-1594	55	18	aiming	aim	VERB
ecletica-1594	55	19	to	to	PART
ecletica-1594	55	20	reduce	reduce	VERB
ecletica-1594	55	21	likely	likely	ADJ
ecletica-1594	55	22	challenges	challenge	NOUN
ecletica-1594	55	23	associated	associate	VERB
ecletica-1594	55	24	with	with	ADP
ecletica-1594	55	25	clinical	clinical	ADJ
ecletica-1594	55	26	trial	trial	NOUN
ecletica-1594	55	27	treatments	treatment	NOUN
ecletica-1594	55	28	(	(	PUNCT
ecletica-1594	55	29	darvas	darvas	PROPN
ecletica-1594	55	30	et	et	PROPN
ecletica-1594	55	31	al	al	PROPN
ecletica-1594	55	32	.	.	PROPN
ecletica-1594	55	33	,	,	PUNCT
ecletica-1594	55	34	2002	2002	NUM
ecletica-1594	55	35	)	)	PUNCT
ecletica-1594	55	36	.	.	PUNCT
ecletica-1594	56	1	3	3	X
ecletica-1594	56	2	.	.	NOUN
ecletica-1594	56	3	results	result	NOUN
ecletica-1594	56	4	and	and	CCONJ
ecletica-1594	56	5	discussion	discussion	NOUN
ecletica-1594	56	6	3.1	3.1	NUM
ecletica-1594	56	7	.	.	PUNCT
ecletica-1594	57	1	molecular	molecular	ADJ
ecletica-1594	57	2	quantum	quantum	NOUN
ecletica-1594	57	3	reactivity	reactivity	NOUN
ecletica-1594	57	4	descriptors	descriptor	VERB
ecletica-1594	57	5	the	the	DET
ecletica-1594	57	6	frontier	frontier	NOUN
ecletica-1594	57	7	orbital	orbital	NOUN
ecletica-1594	57	8	(	(	PUNCT
ecletica-1594	57	9	the	the	DET
ecletica-1594	57	10	homo	homo	NOUN
ecletica-1594	57	11	and	and	CCONJ
ecletica-1594	57	12	lumo	lumo	NOUN
ecletica-1594	57	13	)	)	PUNCT
ecletica-1594	57	14	energies	energy	NOUN
ecletica-1594	57	15	are	be	AUX
ecletica-1594	57	16	very	very	ADV
ecletica-1594	57	17	essential	essential	ADJ
ecletica-1594	57	18	to	to	ADP
ecletica-1594	57	19	the	the	DET
ecletica-1594	57	20	molecular	molecular	ADJ
ecletica-1594	57	21	stability	stability	NOUN
ecletica-1594	57	22	and	and	CCONJ
ecletica-1594	57	23	responses	response	NOUN
ecletica-1594	57	24	to	to	ADP
ecletica-1594	57	25	the	the	DET
ecletica-1594	57	26	surrounding	surround	VERB
ecletica-1594	57	27	molecules	molecule	NOUN
ecletica-1594	57	28	,	,	PUNCT
ecletica-1594	57	29	where	where	SCONJ
ecletica-1594	57	30	homo	homo	NOUN
ecletica-1594	57	31	and	and	CCONJ
ecletica-1594	57	32	lumo	lumo	NOUN
ecletica-1594	57	33	represent	represent	VERB
ecletica-1594	57	34	the	the	DET
ecletica-1594	57	35	highest	high	ADJ
ecletica-1594	57	36	occupied	occupy	VERB
ecletica-1594	57	37	molecular	molecular	ADJ
ecletica-1594	57	38	orbital	orbital	NOUN
ecletica-1594	57	39	and	and	CCONJ
ecletica-1594	57	40	the	the	DET
ecletica-1594	57	41	lowest	low	ADJ
ecletica-1594	57	42	unoccupied	unoccupied	ADJ
ecletica-1594	57	43	molecular	molecular	ADJ
ecletica-1594	57	44	orbital	orbital	NOUN
ecletica-1594	57	45	,	,	PUNCT
ecletica-1594	57	46	respectively	respectively	ADV
ecletica-1594	57	47	.	.	PUNCT
ecletica-1594	58	1	the	the	DET
ecletica-1594	58	2	high	high	ADJ
ecletica-1594	58	3	homo	homo	NOUN
ecletica-1594	58	4	energy	energy	NOUN
ecletica-1594	58	5	(	(	PUNCT
ecletica-1594	58	6	or	or	CCONJ
ecletica-1594	58	7	low	low	ADJ
ecletica-1594	58	8	ionization	ionization	NOUN
ecletica-1594	58	9	energy	energy	NOUN
ecletica-1594	58	10	,	,	PUNCT
ecletica-1594	58	11	ip	ip	NOUN
ecletica-1594	58	12	)	)	PUNCT
ecletica-1594	58	13	typifies	typify	VERB
ecletica-1594	58	14	the	the	DET
ecletica-1594	58	15	enhancement	enhancement	NOUN
ecletica-1594	58	16	of	of	ADP
ecletica-1594	58	17	a	a	DET
ecletica-1594	58	18	ligand	ligand	NOUN
ecletica-1594	58	19	to	to	PART
ecletica-1594	58	20	donate	donate	VERB
ecletica-1594	58	21	electrons	electron	NOUN
ecletica-1594	58	22	to	to	ADP
ecletica-1594	58	23	the	the	DET
ecletica-1594	58	24	neighboring	neighboring	NOUN
ecletica-1594	58	25	molecule	molecule	NOUN
ecletica-1594	58	26	.	.	PUNCT
ecletica-1594	59	1	lower	low	ADJ
ecletica-1594	59	2	lumo	lumo	NOUN
ecletica-1594	59	3	energy	energy	NOUN
ecletica-1594	59	4	,	,	PUNCT
ecletica-1594	59	5	on	on	ADP
ecletica-1594	59	6	the	the	DET
ecletica-1594	59	7	other	other	ADJ
ecletica-1594	59	8	hand	hand	NOUN
ecletica-1594	59	9	(	(	PUNCT
ecletica-1594	59	10	or	or	CCONJ
ecletica-1594	59	11	high	high	ADJ
ecletica-1594	59	12	electron	electron	NOUN
ecletica-1594	59	13	affinity	affinity	NOUN
ecletica-1594	59	14	,	,	PUNCT
ecletica-1594	59	15	ea	ea	X
ecletica-1594	59	16	)	)	PUNCT
ecletica-1594	59	17	,	,	PUNCT
ecletica-1594	59	18	represents	represent	VERB
ecletica-1594	59	19	a	a	DET
ecletica-1594	59	20	ligand	ligand	NOUN
ecletica-1594	59	21	's	's	PART
ecletica-1594	59	22	ability	ability	NOUN
ecletica-1594	59	23	to	to	PART
ecletica-1594	59	24	accept	accept	VERB
ecletica-1594	59	25	electrons	electron	NOUN
ecletica-1594	59	26	from	from	ADP
ecletica-1594	59	27	the	the	DET
ecletica-1594	59	28	neighboring	neighboring	NOUN
ecletica-1594	59	29	compounds	compound	NOUN
ecletica-1594	59	30	(	(	PUNCT
ecletica-1594	59	31	oyebamiji	oyebamiji	NOUN
ecletica-1594	59	32	and	and	CCONJ
ecletica-1594	59	33	semire	semire	NOUN
ecletica-1594	59	34	,	,	PUNCT
ecletica-1594	59	35	2016	2016	NUM
ecletica-1594	59	36	)	)	PUNCT
ecletica-1594	59	37	.	.	PUNCT
ecletica-1594	60	1	the	the	DET
ecletica-1594	60	2	lower	low	ADJ
ecletica-1594	60	3	ip	ip	NOUN
ecletica-1594	60	4	values	value	NOUN
ecletica-1594	60	5	revealed	reveal	VERB
ecletica-1594	60	6	that	that	SCONJ
ecletica-1594	60	7	nah	nah	INTJ
ecletica-1594	60	8	(	(	PUNCT
ecletica-1594	60	9	4.05	4.05	NUM
ecletica-1594	60	10	ev	ev	NOUN
ecletica-1594	60	11	)	)	PUNCT
ecletica-1594	60	12	,	,	PUNCT
ecletica-1594	60	13	5ad	5ad	NOUN
ecletica-1594	60	14	(	(	PUNCT
ecletica-1594	60	15	5.47	5.47	NUM
ecletica-1594	60	16	ev	ev	NOUN
ecletica-1594	60	17	)	)	PUNCT
ecletica-1594	60	18	,	,	PUNCT
ecletica-1594	60	19	and	and	CCONJ
ecletica-1594	60	20	nan	nan	PROPN
ecletica-1594	60	21	(	(	PUNCT
ecletica-1594	60	22	5.75	5.75	NUM
ecletica-1594	60	23	ev	ev	NOUN
ecletica-1594	60	24	)	)	PUNCT
ecletica-1594	60	25	should	should	AUX
ecletica-1594	60	26	be	be	AUX
ecletica-1594	60	27	able	able	ADJ
ecletica-1594	60	28	to	to	PART
ecletica-1594	60	29	donate	donate	VERB
ecletica-1594	60	30	electrons	electron	NOUN
ecletica-1594	60	31	readily	readily	ADV
ecletica-1594	60	32	to	to	ADP
ecletica-1594	60	33	the	the	DET
ecletica-1594	60	34	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	X
ecletica-1594	60	35	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	X
ecletica-1594	60	36	http://biosig.unimelb.edu.au/pkcsm/prediction	http://biosig.unimelb.edu.au/pkcsm/prediction	NOUN
ecletica-1594	60	37	original	original	ADJ
ecletica-1594	60	38	article	article	NOUN
ecletica-1594	60	39	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	X
ecletica-1594	60	40	issn	issn	VERB
ecletica-1594	60	41	1678	1678	NUM
ecletica-1594	60	42	-	-	SYM
ecletica-1594	60	43	4618	4618	NUM
ecletica-1594	60	44	page	page	NOUN
ecletica-1594	60	45	4/14	4/14	NUM
ecletica-1594	60	46	surrounding	surround	VERB
ecletica-1594	60	47	molecule	molecule	NOUN
ecletica-1594	60	48	than	than	ADP
ecletica-1594	60	49	penicillin	penicillin	NOUN
ecletica-1594	60	50	(	(	PUNCT
ecletica-1594	60	51	9.61	9.61	NUM
ecletica-1594	60	52	ev	ev	VERB
ecletica-1594	60	53	)	)	PUNCT
ecletica-1594	60	54	and	and	CCONJ
ecletica-1594	60	55	sulfamethoxazole	sulfamethoxazole	NOUN
ecletica-1594	60	56	(	(	PUNCT
ecletica-1594	60	57	5.93	5.93	NUM
ecletica-1594	60	58	ev	ev	NOUN
ecletica-1594	60	59	)	)	PUNCT
ecletica-1594	60	60	(	(	PUNCT
ecletica-1594	60	61	oyeneyin	oyeneyin	PROPN
ecletica-1594	60	62	,	,	PUNCT
ecletica-1594	60	63	2023	2023	NUM
ecletica-1594	60	64	)	)	PUNCT
ecletica-1594	60	65	.	.	PUNCT
ecletica-1594	61	1	also	also	ADV
ecletica-1594	61	2	,	,	PUNCT
ecletica-1594	61	3	all	all	DET
ecletica-1594	61	4	the	the	DET
ecletica-1594	61	5	compounds	compound	NOUN
ecletica-1594	61	6	,	,	PUNCT
ecletica-1594	61	7	especially	especially	ADV
ecletica-1594	61	8	nal	nal	ADJ
ecletica-1594	61	9	,	,	PUNCT
ecletica-1594	61	10	nah	nah	INTJ
ecletica-1594	61	11	,	,	PUNCT
ecletica-1594	61	12	5ad	5ad	PROPN
ecletica-1594	61	13	,	,	PUNCT
ecletica-1594	61	14	nam	nam	PROPN
ecletica-1594	61	15	,	,	PUNCT
ecletica-1594	61	16	and	and	CCONJ
ecletica-1594	61	17	nan	nan	PROPN
ecletica-1594	61	18	,	,	PUNCT
ecletica-1594	61	19	should	should	AUX
ecletica-1594	61	20	have	have	AUX
ecletica-1594	61	21	enhanced	enhance	VERB
ecletica-1594	61	22	electron	electron	NOUN
ecletica-1594	61	23	-	-	PUNCT
ecletica-1594	61	24	accepting	accept	VERB
ecletica-1594	61	25	tendency	tendency	NOUN
ecletica-1594	61	26	from	from	ADP
ecletica-1594	61	27	the	the	DET
ecletica-1594	61	28	neighboring	neighboring	NOUN
ecletica-1594	61	29	molecule	molecule	NOUN
ecletica-1594	61	30	(	(	PUNCT
ecletica-1594	61	31	table	table	NOUN
ecletica-1594	61	32	1	1	NUM
ecletica-1594	61	33	)	)	PUNCT
ecletica-1594	61	34	.	.	PUNCT
ecletica-1594	62	1	low	low	ADJ
ecletica-1594	62	2	polarizability	polarizability	NOUN
ecletica-1594	62	3	,	,	PUNCT
ecletica-1594	62	4	low	low	ADJ
ecletica-1594	62	5	reactivity	reactivity	NOUN
ecletica-1594	62	6	,	,	PUNCT
ecletica-1594	62	7	stronger	strong	ADJ
ecletica-1594	62	8	stabilization	stabilization	NOUN
ecletica-1594	62	9	and	and	CCONJ
ecletica-1594	62	10	interactions	interaction	NOUN
ecletica-1594	62	11	between	between	ADP
ecletica-1594	62	12	a	a	DET
ecletica-1594	62	13	molecule	molecule	NOUN
ecletica-1594	62	14	and	and	CCONJ
ecletica-1594	62	15	its	its	PRON
ecletica-1594	62	16	receptor	receptor	NOUN
ecletica-1594	62	17	favor	favor	VERB
ecletica-1594	62	18	molecules	molecule	NOUN
ecletica-1594	62	19	with	with	ADP
ecletica-1594	62	20	a	a	DET
ecletica-1594	62	21	larger	large	ADJ
ecletica-1594	62	22	energy	energy	NOUN
ecletica-1594	62	23	gap	gap	NOUN
ecletica-1594	62	24	(	(	PUNCT
ecletica-1594	62	25	eg	eg	NOUN
ecletica-1594	62	26	)	)	PUNCT
ecletica-1594	62	27	,	,	PUNCT
ecletica-1594	62	28	whereas	whereas	SCONJ
ecletica-1594	62	29	a	a	DET
ecletica-1594	62	30	smaller	small	ADJ
ecletica-1594	62	31	energy	energy	NOUN
ecletica-1594	62	32	gap	gap	NOUN
ecletica-1594	62	33	favors	favor	VERB
ecletica-1594	62	34	high	high	ADJ
ecletica-1594	62	35	reactivity	reactivity	NOUN
ecletica-1594	62	36	,	,	PUNCT
ecletica-1594	62	37	high	high	ADJ
ecletica-1594	62	38	polarizability	polarizability	NOUN
ecletica-1594	62	39	,	,	PUNCT
ecletica-1594	62	40	weaker	weak	ADJ
ecletica-1594	62	41	stabilization	stabilization	NOUN
ecletica-1594	62	42	and	and	CCONJ
ecletica-1594	62	43	interactions	interaction	NOUN
ecletica-1594	62	44	of	of	ADP
ecletica-1594	62	45	a	a	DET
ecletica-1594	62	46	molecule	molecule	NOUN
ecletica-1594	62	47	with	with	ADP
ecletica-1594	62	48	neighboring	neighboring	NOUN
ecletica-1594	62	49	compound	compound	NOUN
ecletica-1594	62	50	.	.	PUNCT
ecletica-1594	63	1	therefore	therefore	ADV
ecletica-1594	63	2	,	,	PUNCT
ecletica-1594	63	3	higher	high	ADJ
ecletica-1594	63	4	values	value	NOUN
ecletica-1594	63	5	,	,	PUNCT
ecletica-1594	63	6	eg	eg	NOUN
ecletica-1594	63	7	,	,	PUNCT
ecletica-1594	63	8	η	η	PROPN
ecletica-1594	63	9	and	and	CCONJ
ecletica-1594	63	10	σ	σ	PROPN
ecletica-1594	63	11	,	,	PUNCT
ecletica-1594	63	12	showed	show	VERB
ecletica-1594	63	13	that	that	SCONJ
ecletica-1594	63	14	penicillin	penicillin	NOUN
ecletica-1594	63	15	and	and	CCONJ
ecletica-1594	63	16	sulfamethoxazole	sulfamethoxazole	NOUN
ecletica-1594	63	17	are	be	AUX
ecletica-1594	63	18	more	more	ADV
ecletica-1594	63	19	stable	stable	ADJ
ecletica-1594	63	20	,	,	PUNCT
ecletica-1594	63	21	which	which	PRON
ecletica-1594	63	22	may	may	AUX
ecletica-1594	63	23	support	support	VERB
ecletica-1594	63	24	strong	strong	ADJ
ecletica-1594	63	25	interactions	interaction	NOUN
ecletica-1594	63	26	,	,	PUNCT
ecletica-1594	63	27	although	although	SCONJ
ecletica-1594	63	28	naj	naj	PROPN
ecletica-1594	63	29	,	,	PUNCT
ecletica-1594	63	30	nai	nai	PROPN
ecletica-1594	63	31	,	,	PUNCT
ecletica-1594	63	32	nak	nak	PROPN
ecletica-1594	63	33	and	and	CCONJ
ecletica-1594	63	34	nam	nam	NOUN
ecletica-1594	63	35	may	may	AUX
ecletica-1594	63	36	also	also	ADV
ecletica-1594	63	37	display	display	VERB
ecletica-1594	63	38	strong	strong	ADJ
ecletica-1594	63	39	interactions	interaction	NOUN
ecletica-1594	63	40	(	(	PUNCT
ecletica-1594	63	41	thanikaivelan	thanikaivelan	NOUN
ecletica-1594	63	42	et	et	PROPN
ecletica-1594	63	43	al	al	PROPN
ecletica-1594	63	44	.	.	PROPN
ecletica-1594	63	45	,	,	PUNCT
ecletica-1594	63	46	2020	2020	NUM
ecletica-1594	63	47	)	)	PUNCT
ecletica-1594	63	48	.	.	PUNCT
ecletica-1594	64	1	the	the	DET
ecletica-1594	64	2	chemical	chemical	ADJ
ecletica-1594	64	3	potential	potential	NOUN
ecletica-1594	64	4	(	(	PUNCT
ecletica-1594	64	5	μ	μ	NOUN
ecletica-1594	64	6	)	)	PUNCT
ecletica-1594	64	7	showed	show	VERB
ecletica-1594	64	8	that	that	SCONJ
ecletica-1594	64	9	all	all	DET
ecletica-1594	64	10	the	the	DET
ecletica-1594	64	11	sulfamidophosphonate	sulfamidophosphonate	NOUN
ecletica-1594	64	12	compounds	compound	NOUN
ecletica-1594	64	13	are	be	AUX
ecletica-1594	64	14	more	more	ADV
ecletica-1594	64	15	likely	likely	ADJ
ecletica-1594	64	16	to	to	PART
ecletica-1594	64	17	interact	interact	VERB
ecletica-1594	64	18	strongly	strongly	ADV
ecletica-1594	64	19	through	through	ADP
ecletica-1594	64	20	electrostatic	electrostatic	ADJ
ecletica-1594	64	21	interactions	interaction	NOUN
ecletica-1594	64	22	with	with	ADP
ecletica-1594	64	23	the	the	DET
ecletica-1594	64	24	receptor	receptor	NOUN
ecletica-1594	64	25	than	than	ADP
ecletica-1594	64	26	the	the	DET
ecletica-1594	64	27	standard	standard	ADJ
ecletica-1594	64	28	drugs	drug	NOUN
ecletica-1594	64	29	(	(	PUNCT
ecletica-1594	64	30	penicillin	penicillin	NOUN
ecletica-1594	64	31	and	and	CCONJ
ecletica-1594	64	32	sulfamethoxazole	sulfamethoxazole	NOUN
ecletica-1594	64	33	)	)	PUNCT
ecletica-1594	64	34	.	.	PUNCT
ecletica-1594	65	1	the	the	DET
ecletica-1594	65	2	difference	difference	NOUN
ecletica-1594	65	3	between	between	ADP
ecletica-1594	65	4	electron	electron	NOUN
ecletica-1594	65	5	-	-	PUNCT
ecletica-1594	65	6	donating	donate	VERB
ecletica-1594	65	7	ability	ability	NOUN
ecletica-1594	65	8	(	(	PUNCT
ecletica-1594	65	9	ω	ω	NOUN
ecletica-1594	65	10	–	–	PUNCT
ecletica-1594	65	11	)	)	PUNCT
ecletica-1594	65	12	and	and	CCONJ
ecletica-1594	65	13	electronaccepting	electronaccepte	VERB
ecletica-1594	65	14	ability	ability	NOUN
ecletica-1594	65	15	(	(	PUNCT
ecletica-1594	65	16	ω+	ω+	NOUN
ecletica-1594	65	17	)	)	PUNCT
ecletica-1594	65	18	is	be	AUX
ecletica-1594	65	19	∣∆ω∣	∣∆ω∣	NOUN
ecletica-1594	65	20	,	,	PUNCT
ecletica-1594	65	21	which	which	PRON
ecletica-1594	65	22	measures	measure	VERB
ecletica-1594	65	23	the	the	DET
ecletica-1594	65	24	total	total	ADJ
ecletica-1594	65	25	responsiveness	responsiveness	NOUN
ecletica-1594	65	26	of	of	ADP
ecletica-1594	65	27	a	a	DET
ecletica-1594	65	28	molecule	molecule	NOUN
ecletica-1594	65	29	to	to	ADP
ecletica-1594	65	30	its	its	PRON
ecletica-1594	65	31	surroundings	surrounding	NOUN
ecletica-1594	65	32	.	.	PUNCT
ecletica-1594	66	1	higher	high	ADJ
ecletica-1594	66	2	values	value	NOUN
ecletica-1594	66	3	typify	typify	VERB
ecletica-1594	66	4	a	a	DET
ecletica-1594	66	5	strong	strong	ADJ
ecletica-1594	66	6	response	response	NOUN
ecletica-1594	66	7	leading	lead	VERB
ecletica-1594	66	8	to	to	ADP
ecletica-1594	66	9	strong	strong	ADJ
ecletica-1594	66	10	interactions	interaction	NOUN
ecletica-1594	66	11	between	between	ADP
ecletica-1594	66	12	the	the	DET
ecletica-1594	66	13	molecule	molecule	NOUN
ecletica-1594	66	14	and	and	CCONJ
ecletica-1594	66	15	its	its	PRON
ecletica-1594	66	16	surroundings	surrounding	NOUN
ecletica-1594	66	17	(	(	PUNCT
ecletica-1594	66	18	asibor	asibor	NOUN
ecletica-1594	66	19	et	et	PROPN
ecletica-1594	66	20	al	al	PROPN
ecletica-1594	66	21	.	.	PROPN
ecletica-1594	66	22	,	,	PUNCT
ecletica-1594	66	23	2024	2024	NUM
ecletica-1594	66	24	)	)	PUNCT
ecletica-1594	66	25	.	.	PUNCT
ecletica-1594	67	1	therefore	therefore	ADV
ecletica-1594	67	2	,	,	PUNCT
ecletica-1594	67	3	nal	nal	PROPN
ecletica-1594	67	4	,	,	PUNCT
ecletica-1594	67	5	nam	nam	PROPN
ecletica-1594	67	6	,	,	PUNCT
ecletica-1594	67	7	nak	nak	PROPN
ecletica-1594	67	8	,	,	PUNCT
ecletica-1594	67	9	naj	naj	NOUN
ecletica-1594	67	10	,	,	PUNCT
ecletica-1594	67	11	and	and	CCONJ
ecletica-1594	67	12	5ad	5ad	NOUN
ecletica-1594	67	13	are	be	AUX
ecletica-1594	67	14	likely	likely	ADV
ecletica-1594	67	15	disposed	dispose	VERB
ecletica-1594	67	16	of	of	ADP
ecletica-1594	67	17	stronger	strong	ADJ
ecletica-1594	67	18	interactions	interaction	NOUN
ecletica-1594	67	19	with	with	ADP
ecletica-1594	67	20	the	the	DET
ecletica-1594	67	21	receptor	receptor	NOUN
ecletica-1594	67	22	than	than	ADP
ecletica-1594	67	23	penicillin	penicillin	NOUN
ecletica-1594	67	24	and	and	CCONJ
ecletica-1594	67	25	sulfamethoxazole	sulfamethoxazole	NOUN
ecletica-1594	67	26	.	.	PUNCT
ecletica-1594	68	1	table	table	NOUN
ecletica-1594	68	2	1	1	NUM
ecletica-1594	68	3	.	.	PUNCT
ecletica-1594	68	4	quantum	quantum	ADJ
ecletica-1594	68	5	chemical	chemical	NOUN
ecletica-1594	68	6	descriptors	descriptor	NOUN
ecletica-1594	68	7	of	of	ADP
ecletica-1594	68	8	sulfamidophosphonates	sulfamidophosphonate	NOUN
ecletica-1594	68	9	using	use	VERB
ecletica-1594	68	10	b3lyp/6	b3lyp/6	PROPN
ecletica-1594	68	11	-	-	X
ecletica-1594	68	12	31	31	NUM
ecletica-1594	68	13	g	g	NOUN
ecletica-1594	68	14	*	*	PROPN
ecletica-1594	68	15	*	*	NOUN
ecletica-1594	68	16	.	.	PUNCT
ecletica-1594	68	17	ip	ip	PROPN
ecletica-1594	68	18	ea	ea	PROPN
ecletica-1594	68	19	eg	eg	PROPN
ecletica-1594	68	20	η	η	PROPN
ecletica-1594	68	21	σ	σ	PROPN
ecletica-1594	68	22	μ	μ	PROPN
ecletica-1594	68	23	ω	ω	X
ecletica-1594	68	24	ωω+	ωω+	NOUN
ecletica-1594	69	1	|∆𝝎	|∆𝝎	NOUN
ecletica-1594	69	2	|	|	NOUN
ecletica-1594	69	3	=	=	SYM
ecletica-1594	69	4	(	(	PUNCT
ecletica-1594	69	5	𝝎+	𝝎+	ADJ
ecletica-1594	69	6	−	−	PROPN
ecletica-1594	69	7	𝝎−	𝝎−	PROPN
ecletica-1594	69	8	)	)	PUNCT
ecletica-1594	69	9	nah	nah	CCONJ
ecletica-1594	69	10	4.05	4.05	NUM
ecletica-1594	69	11	2.68	2.68	NUM
ecletica-1594	69	12	1.37	1.37	NUM
ecletica-1594	69	13	0.685	0.685	NUM
ecletica-1594	69	14	0.730	0.730	NUM
ecletica-1594	69	15	–	–	PUNCT
ecletica-1594	69	16	3.365	3.365	NUM
ecletica-1594	69	17	8.265	8.265	NUM
ecletica-1594	69	18	10.033	10.033	NUM
ecletica-1594	69	19	6.668	6.668	NUM
ecletica-1594	69	20	3.365	3.365	NUM
ecletica-1594	69	21	nai	nai	ADV
ecletica-1594	69	22	6.26	6.26	NUM
ecletica-1594	69	23	1.81	1.81	NUM
ecletica-1594	69	24	4.45	4.45	NUM
ecletica-1594	69	25	2.225	2.225	NUM
ecletica-1594	69	26	0.225	0.225	NUM
ecletica-1594	69	27	–	–	PUNCT
ecletica-1594	69	28	4.035	4.035	NUM
ecletica-1594	69	29	3.659	3.659	NUM
ecletica-1594	69	30	5.954	5.954	NUM
ecletica-1594	69	31	1.919	1.919	NUM
ecletica-1594	69	32	4.035	4.035	NUM
ecletica-1594	69	33	naj	naj	NUM
ecletica-1594	69	34	6.11	6.11	NUM
ecletica-1594	69	35	1.55	1.55	NUM
ecletica-1594	69	36	4.56	4.56	NUM
ecletica-1594	69	37	2.280	2.280	NUM
ecletica-1594	69	38	0.219	0.219	NUM
ecletica-1594	69	39	–	–	PUNCT
ecletica-1594	69	40	3.830	3.830	NUM
ecletica-1594	69	41	3.217	3.217	NUM
ecletica-1594	69	42	5.417	5.417	NUM
ecletica-1594	69	43	1.587	1.587	NUM
ecletica-1594	69	44	3.830	3.830	NUM
ecletica-1594	69	45	nak	nak	NOUN
ecletica-1594	69	46	6.33	6.33	NUM
ecletica-1594	69	47	1.80	1.80	NUM
ecletica-1594	69	48	4.53	4.53	NUM
ecletica-1594	69	49	2.265	2.265	NUM
ecletica-1594	69	50	0.221	0.221	NUM
ecletica-1594	69	51	–	–	PUNCT
ecletica-1594	69	52	4.065	4.065	NUM
ecletica-1594	69	53	3.648	3.648	NUM
ecletica-1594	69	54	5.963	5.963	NUM
ecletica-1594	69	55	1.898	1.898	NUM
ecletica-1594	69	56	4.065	4.065	NUM
ecletica-1594	69	57	nal	nal	ADJ
ecletica-1594	69	58	6.47	6.47	NUM
ecletica-1594	69	59	4.01	4.01	NUM
ecletica-1594	69	60	2.46	2.46	NUM
ecletica-1594	69	61	1.230	1.230	NUM
ecletica-1594	69	62	0.407	0.407	NUM
ecletica-1594	69	63	–	–	PUNCT
ecletica-1594	69	64	5.240	5.240	NUM
ecletica-1594	69	65	11.162	11.162	NUM
ecletica-1594	69	66	13.935	13.935	NUM
ecletica-1594	69	67	8.695	8.695	NUM
ecletica-1594	69	68	5.240	5.240	NUM
ecletica-1594	69	69	nam	nam	NOUN
ecletica-1594	69	70	6.22	6.22	NUM
ecletica-1594	69	71	2.03	2.03	NUM
ecletica-1594	69	72	4.19	4.19	NUM
ecletica-1594	69	73	2.095	2.095	NUM
ecletica-1594	69	74	0.239	0.239	NUM
ecletica-1594	69	75	–	–	PUNCT
ecletica-1594	69	76	4.125	4.125	NUM
ecletica-1594	69	77	4.061	4.061	NUM
ecletica-1594	69	78	6.385	6.385	NUM
ecletica-1594	69	79	2.260	2.260	NUM
ecletica-1594	69	80	4.125	4.125	NUM
ecletica-1594	69	81	nan	nan	NOUN
ecletica-1594	69	82	5.75	5.75	NUM
ecletica-1594	69	83	2.03	2.03	NUM
ecletica-1594	69	84	3.72	3.72	NUM
ecletica-1594	69	85	1.860	1.860	NUM
ecletica-1594	69	86	0.269	0.269	NUM
ecletica-1594	69	87	–	–	PUNCT
ecletica-1594	69	88	3.890	3.890	NUM
ecletica-1594	69	89	4.068	4.068	NUM
ecletica-1594	69	90	6.245	6.245	NUM
ecletica-1594	69	91	2.355	2.355	NUM
ecletica-1594	69	92	3.890	3.890	NUM
ecletica-1594	69	93	5ad	5ad	NOUN
ecletica-1594	69	94	5.47	5.47	NUM
ecletica-1594	69	95	2.54	2.54	NUM
ecletica-1594	69	96	2.93	2.93	NUM
ecletica-1594	69	97	1.465	1.465	NUM
ecletica-1594	69	98	0.341	0.341	NUM
ecletica-1594	69	99	–	–	PUNCT
ecletica-1594	69	100	4.005	4.005	NUM
ecletica-1594	69	101	5.474	5.474	NUM
ecletica-1594	69	102	7.660	7.660	NUM
ecletica-1594	69	103	3.655	3.655	NUM
ecletica-1594	69	104	4.005	4.005	NUM
ecletica-1594	69	105	penicillin	penicillin	NOUN
ecletica-1594	69	106	9.61	9.61	NUM
ecletica-1594	69	107	–	–	PUNCT
ecletica-1594	69	108	3.34	3.34	NUM
ecletica-1594	69	109	12.95	12.95	NUM
ecletica-1594	69	110	6.475	6.475	NUM
ecletica-1594	69	111	0.077	0.077	NUM
ecletica-1594	69	112	–	–	PUNCT
ecletica-1594	69	113	3.135	3.135	NUM
ecletica-1594	69	114	0.759	0.759	NUM
ecletica-1594	69	115	3.136	3.136	NUM
ecletica-1594	69	116	0.001	0.001	NUM
ecletica-1594	69	117	3.135	3.135	NUM
ecletica-1594	69	118	sulfamethoxazole	sulfamethoxazole	NOUN
ecletica-1594	69	119	5.93	5.93	NUM
ecletica-1594	69	120	0.51	0.51	NUM
ecletica-1594	69	121	5.42	5.42	NUM
ecletica-1594	69	122	2.710	2.710	NUM
ecletica-1594	69	123	0.185	0.185	NUM
ecletica-1594	69	124	–	–	PUNCT
ecletica-1594	69	125	3.220	3.220	NUM
ecletica-1594	69	126	1.913	1.913	NUM
ecletica-1594	69	127	3.862	3.862	NUM
ecletica-1594	69	128	0.642	0.642	NUM
ecletica-1594	69	129	3.220	3.220	NUM
ecletica-1594	69	130	source	source	NOUN
ecletica-1594	69	131	:	:	PUNCT
ecletica-1594	69	132	elaborated	elaborate	VERB
ecletica-1594	69	133	by	by	ADP
ecletica-1594	69	134	the	the	DET
ecletica-1594	69	135	authors	author	NOUN
ecletica-1594	69	136	.	.	PUNCT
ecletica-1594	70	1	3.2	3.2	NUM
ecletica-1594	70	2	.	.	PUNCT
ecletica-1594	71	1	docking	dock	VERB
ecletica-1594	71	2	orientation	orientation	NOUN
ecletica-1594	71	3	and	and	CCONJ
ecletica-1594	71	4	binding	bind	VERB
ecletica-1594	71	5	affinity	affinity	NOUN
ecletica-1594	71	6	blai	blai	NOUN
ecletica-1594	71	7	is	be	AUX
ecletica-1594	71	8	a	a	DET
ecletica-1594	71	9	repressor	repressor	NOUN
ecletica-1594	71	10	,	,	PUNCT
ecletica-1594	71	11	as	as	ADV
ecletica-1594	71	12	well	well	ADV
ecletica-1594	71	13	as	as	ADP
ecletica-1594	71	14	a	a	DET
ecletica-1594	71	15	beta	beta	NOUN
ecletica-1594	71	16	-	-	PUNCT
ecletica-1594	71	17	lactamase	lactamase	NOUN
ecletica-1594	71	18	that	that	PRON
ecletica-1594	71	19	is	be	AUX
ecletica-1594	71	20	responsible	responsible	ADJ
ecletica-1594	71	21	for	for	ADP
ecletica-1594	71	22	penicillin	penicillin	NOUN
ecletica-1594	71	23	resistance	resistance	NOUN
ecletica-1594	71	24	in	in	ADP
ecletica-1594	71	25	staphylococcus	staphylococcus	NOUN
ecletica-1594	71	26	aureus	aureus	NOUN
ecletica-1594	71	27	and	and	CCONJ
ecletica-1594	71	28	essential	essential	ADJ
ecletica-1594	71	29	for	for	ADP
ecletica-1594	71	30	staphylococcus	staphylococcus	NOUN
ecletica-1594	71	31	aureus	aureus	NOUN
ecletica-1594	71	32	reproduction	reproduction	NOUN
ecletica-1594	71	33	.	.	PUNCT
ecletica-1594	72	1	the	the	DET
ecletica-1594	72	2	blai	blai	PROPN
ecletica-1594	72	3	repressor	repressor	NOUN
ecletica-1594	72	4	in	in	ADP
ecletica-1594	72	5	complex	complex	NOUN
ecletica-1594	72	6	with	with	ADP
ecletica-1594	72	7	dna	dna	PROPN
ecletica-1594	72	8	(	(	PUNCT
ecletica-1594	72	9	pdb	pdb	PROPN
ecletica-1594	72	10	i	i	PROPN
ecletica-1594	72	11	d	d	PROPN
ecletica-1594	72	12	:	:	PUNCT
ecletica-1594	72	13	1xsd	1xsd	X
ecletica-1594	72	14	)	)	PUNCT
ecletica-1594	72	15	was	be	AUX
ecletica-1594	72	16	docked	dock	VERB
ecletica-1594	72	17	with	with	ADP
ecletica-1594	72	18	sulfamidophosphonate	sulfamidophosphonate	ADJ
ecletica-1594	72	19	derivatives	derivative	NOUN
ecletica-1594	72	20	.	.	PUNCT
ecletica-1594	73	1	results	result	NOUN
ecletica-1594	73	2	were	be	AUX
ecletica-1594	73	3	presented	present	VERB
ecletica-1594	73	4	in	in	ADP
ecletica-1594	73	5	table	table	NOUN
ecletica-1594	73	6	2	2	NUM
ecletica-1594	73	7	and	and	CCONJ
ecletica-1594	73	8	fig	fig	NOUN
ecletica-1594	73	9	.	.	PUNCT
ecletica-1594	74	1	2	2	X
ecletica-1594	74	2	.	.	X
ecletica-1594	74	3	the	the	DET
ecletica-1594	74	4	binding	bind	VERB
ecletica-1594	74	5	affinities	affinity	NOUN
ecletica-1594	74	6	for	for	ADP
ecletica-1594	74	7	all	all	DET
ecletica-1594	74	8	the	the	DET
ecletica-1594	74	9	studied	study	VERB
ecletica-1594	74	10	ligands	ligand	NOUN
ecletica-1594	74	11	with	with	ADP
ecletica-1594	74	12	1xsd	1xsd	PROPN
ecletica-1594	74	13	ranged	range	VERB
ecletica-1594	74	14	from	from	ADP
ecletica-1594	74	15	–	–	PUNCT
ecletica-1594	74	16	17.2	17.2	NUM
ecletica-1594	74	17	(	(	PUNCT
ecletica-1594	74	18	nam	nam	NOUN
ecletica-1594	74	19	)	)	PUNCT
ecletica-1594	74	20	to	to	ADP
ecletica-1594	74	21	–	–	PUNCT
ecletica-1594	74	22	29.7	29.7	NUM
ecletica-1594	74	23	(	(	PUNCT
ecletica-1594	74	24	nal	nal	PROPN
ecletica-1594	74	25	)	)	PUNCT
ecletica-1594	74	26	kj	kj	PROPN
ecletica-1594	74	27	/	/	SYM
ecletica-1594	74	28	mol	mol	PROPN
ecletica-1594	74	29	,	,	PUNCT
ecletica-1594	74	30	these	these	PRON
ecletica-1594	74	31	inferred	infer	VERB
ecletica-1594	74	32	that	that	SCONJ
ecletica-1594	74	33	inhibitory	inhibitory	ADJ
ecletica-1594	74	34	constants	constant	NOUN
ecletica-1594	74	35	(	(	PUNCT
ecletica-1594	74	36	ki	ki	INTJ
ecletica-1594	74	37	)	)	PUNCT
ecletica-1594	74	38	of	of	ADP
ecletica-1594	74	39	the	the	DET
ecletica-1594	74	40	drugs	drug	NOUN
ecletica-1594	74	41	fall	fall	VERB
ecletica-1594	74	42	between	between	ADP
ecletica-1594	74	43	6.21	6.21	NUM
ecletica-1594	74	44	μmol	μmol	NOUN
ecletica-1594	74	45	/	/	SYM
ecletica-1594	74	46	l	l	NOUN
ecletica-1594	74	47	to	to	ADP
ecletica-1594	74	48	984.0	984.0	NUM
ecletica-1594	74	49	μmol	μmol	NOUN
ecletica-1594	74	50	/	/	SYM
ecletica-1594	74	51	l	l	NOUN
ecletica-1594	74	52	as	as	SCONJ
ecletica-1594	74	53	compared	compare	VERB
ecletica-1594	74	54	to	to	ADP
ecletica-1594	74	55	–	–	PUNCT
ecletica-1594	74	56	25.1	25.1	NUM
ecletica-1594	74	57	kj	kj	NOUN
ecletica-1594	74	58	/	/	SYM
ecletica-1594	74	59	mol	mol	NOUN
ecletica-1594	74	60	for	for	ADP
ecletica-1594	74	61	penicillin	penicillin	NOUN
ecletica-1594	74	62	,	,	PUNCT
ecletica-1594	74	63	used	use	VERB
ecletica-1594	74	64	as	as	ADP
ecletica-1594	74	65	standard	standard	ADJ
ecletica-1594	74	66	(	(	PUNCT
ecletica-1594	74	67	table	table	NOUN
ecletica-1594	74	68	2	2	NUM
ecletica-1594	74	69	)	)	PUNCT
ecletica-1594	74	70	.	.	PUNCT
ecletica-1594	75	1	the	the	DET
ecletica-1594	75	2	h	h	NOUN
ecletica-1594	75	3	-	-	PUNCT
ecletica-1594	75	4	bond	bond	NOUN
ecletica-1594	75	5	distances	distance	NOUN
ecletica-1594	75	6	between	between	ADP
ecletica-1594	75	7	amino	amino	NOUN
ecletica-1594	75	8	acid	acid	NOUN
ecletica-1594	75	9	residues	residue	NOUN
ecletica-1594	75	10	in	in	ADP
ecletica-1594	75	11	the	the	DET
ecletica-1594	75	12	binding	bind	VERB
ecletica-1594	75	13	purse	purse	NOUN
ecletica-1594	75	14	and	and	CCONJ
ecletica-1594	75	15	ligands	ligand	NOUN
ecletica-1594	75	16	ranged	range	VERB
ecletica-1594	75	17	from	from	ADP
ecletica-1594	75	18	1.9	1.9	NUM
ecletica-1594	75	19	to	to	ADP
ecletica-1594	75	20	3.50	3.50	NUM
ecletica-1594	75	21	å	å	NOUN
ecletica-1594	75	22	.	.	PUNCT
ecletica-1594	76	1	they	they	PRON
ecletica-1594	76	2	exhibited	exhibit	VERB
ecletica-1594	76	3	other	other	ADJ
ecletica-1594	76	4	non	non	ADJ
ecletica-1594	76	5	-	-	ADJ
ecletica-1594	76	6	bonding	bonding	ADJ
ecletica-1594	76	7	interactions	interaction	NOUN
ecletica-1594	76	8	with	with	ADP
ecletica-1594	76	9	1xsd	1xsd	PRON
ecletica-1594	76	10	receptor	receptor	NOUN
ecletica-1594	76	11	(	(	PUNCT
ecletica-1594	76	12	fig	fig	NOUN
ecletica-1594	76	13	.	.	PUNCT
ecletica-1594	77	1	2	2	NUM
ecletica-1594	77	2	)	)	PUNCT
ecletica-1594	77	3	.	.	PUNCT
ecletica-1594	78	1	compound	compound	NOUN
ecletica-1594	78	2	/	/	SYM
ecletica-1594	78	3	ligand	ligand	NOUN
ecletica-1594	78	4	nal	nal	NOUN
ecletica-1594	78	5	with	with	ADP
ecletica-1594	78	6	the	the	DET
ecletica-1594	78	7	highest	high	ADJ
ecletica-1594	78	8	binding	bind	VERB
ecletica-1594	78	9	affinity	affinity	NOUN
ecletica-1594	78	10	(	(	PUNCT
ecletica-1594	78	11	–	–	PUNCT
ecletica-1594	78	12	29.7	29.7	NUM
ecletica-1594	78	13	kj	kj	PROPN
ecletica-1594	78	14	/	/	SYM
ecletica-1594	78	15	mol	mol	NOUN
ecletica-1594	78	16	)	)	PUNCT
ecletica-1594	78	17	is	be	AUX
ecletica-1594	78	18	hydrogen	hydrogen	NOUN
ecletica-1594	78	19	bonded	bond	VERB
ecletica-1594	78	20	with	with	ADP
ecletica-1594	78	21	arg'60	arg'60	PROPN
ecletica-1594	78	22	,	,	PUNCT
ecletica-1594	78	23	tyr'69	tyr'69	X
ecletica-1594	78	24	,	,	PUNCT
ecletica-1594	78	25	arg'46	arg'46	NOUN
ecletica-1594	78	26	,	,	PUNCT
ecletica-1594	78	27	arg	arg	NOUN
ecletica-1594	78	28	'	'	PUNCT
ecletica-1594	78	29	46	46	NUM
ecletica-1594	78	30	and	and	CCONJ
ecletica-1594	78	31	thr'50	thr'50	NOUN
ecletica-1594	78	32	and	and	CCONJ
ecletica-1594	78	33	showed	show	VERB
ecletica-1594	78	34	interactions	interaction	NOUN
ecletica-1594	78	35	with	with	ADP
ecletica-1594	78	36	ala'27	ala'27	PROPN
ecletica-1594	78	37	,	,	PUNCT
ecletica-1594	78	38	tyr'67	tyr'67	ADV
ecletica-1594	78	39	,	,	PUNCT
ecletica-1594	78	40	tyr'69	tyr'69	X
ecletica-1594	78	41	,	,	PUNCT
ecletica-1594	78	42	arg'46	arg'46	NOUN
ecletica-1594	78	43	,	,	PUNCT
ecletica-1594	78	44	thr'50	thr'50	NOUN
ecletica-1594	78	45	and	and	CCONJ
ecletica-1594	78	46	arg'60	arg'60	PROPN
ecletica-1594	78	47	.	.	PUNCT
ecletica-1594	79	1	nan	nan	PROPN
ecletica-1594	79	2	with	with	ADP
ecletica-1594	79	3	the	the	DET
ecletica-1594	79	4	binding	bind	VERB
ecletica-1594	79	5	affinity	affinity	NOUN
ecletica-1594	79	6	of	of	ADP
ecletica-1594	79	7	–	–	PUNCT
ecletica-1594	79	8	23.8	23.8	NUM
ecletica-1594	79	9	kj	kj	PROPN
ecletica-1594	79	10	/	/	SYM
ecletica-1594	79	11	mol	mol	PROPN
ecletica-1594	79	12	displayed	display	VERB
ecletica-1594	79	13	h	h	NOUN
ecletica-1594	79	14	-	-	PUNCT
ecletica-1594	79	15	bond	bond	NOUN
ecletica-1594	79	16	interactions	interaction	NOUN
ecletica-1594	79	17	with	with	ADP
ecletica-1594	79	18	arg'60	arg'60	PROPN
ecletica-1594	79	19	and	and	CCONJ
ecletica-1594	79	20	tyr	tyr	PROPN
ecletica-1594	79	21	69	69	NUM
ecletica-1594	79	22	,	,	PUNCT
ecletica-1594	79	23	and	and	CCONJ
ecletica-1594	79	24	hydrophobic	hydrophobic	NOUN
ecletica-1594	79	25	interactions	interaction	NOUN
ecletica-1594	79	26	with	with	ADP
ecletica-1594	79	27	arg	arg	NOUN
ecletica-1594	79	28	46	46	NUM
ecletica-1594	79	29	,	,	PUNCT
ecletica-1594	79	30	tyr'69	tyr'69	X
ecletica-1594	79	31	,	,	PUNCT
ecletica-1594	79	32	lys'54	lys'54	X
ecletica-1594	79	33	,	,	PUNCT
ecletica-1594	79	34	ala'27	ala'27	PROPN
ecletica-1594	79	35	,	,	PUNCT
ecletica-1594	79	36	arg'60	arg'60	PROPN
ecletica-1594	79	37	and	and	CCONJ
ecletica-1594	79	38	thr'50	thr'50	NOUN
ecletica-1594	79	39	.	.	PUNCT
ecletica-1594	80	1	also	also	ADV
ecletica-1594	80	2	,	,	PUNCT
ecletica-1594	80	3	nai	nai	PROPN
ecletica-1594	80	4	and	and	CCONJ
ecletica-1594	80	5	nak	nak	NOUN
ecletica-1594	80	6	with	with	ADP
ecletica-1594	80	7	binding	bind	VERB
ecletica-1594	80	8	affinities	affinity	NOUN
ecletica-1594	80	9	of	of	ADP
ecletica-1594	80	10	–	–	PUNCT
ecletica-1594	80	11	28.5	28.5	NUM
ecletica-1594	80	12	and	and	CCONJ
ecletica-1594	80	13	–	–	PUNCT
ecletica-1594	80	14	25.1	25.1	NUM
ecletica-1594	80	15	kj	kj	PROPN
ecletica-1594	80	16	/	/	SYM
ecletica-1594	80	17	mol	mol	PROPN
ecletica-1594	80	18	,	,	PUNCT
ecletica-1594	80	19	respectively	respectively	ADV
ecletica-1594	80	20	,	,	PUNCT
ecletica-1594	80	21	showed	show	VERB
ecletica-1594	80	22	only	only	ADV
ecletica-1594	80	23	hydrophobic	hydrophobic	NOUN
ecletica-1594	80	24	interactions	interaction	NOUN
ecletica-1594	80	25	with	with	ADP
ecletica-1594	80	26	phe'86	phe'86	NUM
ecletica-1594	80	27	,	,	PUNCT
ecletica-1594	80	28	leu'98	leu'98	PRON
ecletica-1594	80	29	,	,	PUNCT
ecletica-1594	80	30	phe'102	phe'102	NOUN
ecletica-1594	80	31	,	,	PUNCT
ecletica-1594	80	32	trp'13	trp'13	NOUN
ecletica-1594	80	33	and	and	CCONJ
ecletica-1594	80	34	ala'83	ala'83	NOUN
ecletica-1594	80	35	for	for	ADP
ecletica-1594	80	36	nai	nai	PROPN
ecletica-1594	80	37	,	,	PUNCT
ecletica-1594	80	38	and	and	CCONJ
ecletica-1594	80	39	lys'69	lys'69	NOUN
ecletica-1594	80	40	,	,	PUNCT
ecletica-1594	80	41	ala'83	ala'83	NOUN
ecletica-1594	80	42	,	,	PUNCT
ecletica-1594	80	43	phe'86	phe'86	PROPN
ecletica-1594	80	44	for	for	ADP
ecletica-1594	80	45	nak	nak	PROPN
ecletica-1594	80	46	.	.	PUNCT
ecletica-1594	81	1	ligand	ligand	PROPN
ecletica-1594	81	2	naj	naj	PROPN
ecletica-1594	81	3	with	with	ADP
ecletica-1594	81	4	a	a	DET
ecletica-1594	81	5	binding	bind	VERB
ecletica-1594	81	6	affinity	affinity	NOUN
ecletica-1594	81	7	of	of	ADP
ecletica-1594	81	8	–	–	PUNCT
ecletica-1594	81	9	28.0	28.0	NUM
ecletica-1594	81	10	kj	kj	NOUN
ecletica-1594	81	11	/	/	SYM
ecletica-1594	81	12	mol	mol	ADP
ecletica-1594	81	13	hydrophobically	hydrophobically	ADV
ecletica-1594	81	14	interacted	interact	VERB
ecletica-1594	81	15	with	with	ADP
ecletica-1594	81	16	lys'54	lys'54	PROPN
ecletica-1594	81	17	arg'60	arg'60	PUNCT
ecletica-1594	81	18	arg'46	arg'46	NOUN
ecletica-1594	81	19	tyr'69	tyr'69	NOUN
ecletica-1594	81	20	,	,	PUNCT
ecletica-1594	81	21	and	and	CCONJ
ecletica-1594	81	22	thr'50	thr'50	NOUN
ecletica-1594	81	23	,	,	PUNCT
ecletica-1594	81	24	as	as	ADV
ecletica-1594	81	25	well	well	ADV
ecletica-1594	81	26	as	as	ADP
ecletica-1594	81	27	h	h	NOUN
ecletica-1594	81	28	-	-	PUNCT
ecletica-1594	81	29	bonding	bonding	NOUN
ecletica-1594	81	30	with	with	ADP
ecletica-1594	81	31	arg’26	arg’26	PROPN
ecletica-1594	81	32	and	and	CCONJ
ecletica-1594	81	33	arg’60	arg’60	PROPN
ecletica-1594	81	34	.	.	PUNCT
ecletica-1594	82	1	also	also	ADV
ecletica-1594	82	2	,	,	PUNCT
ecletica-1594	82	3	nah	nah	INTJ
ecletica-1594	82	4	presented	present	VERB
ecletica-1594	82	5	h	h	NOUN
ecletica-1594	82	6	-	-	PUNCT
ecletica-1594	82	7	bonding	bonding	NOUN
ecletica-1594	82	8	with	with	ADP
ecletica-1594	82	9	arg’26	arg’26	PROPN
ecletica-1594	82	10	and	and	CCONJ
ecletica-1594	82	11	arg’60	arg’60	NUM
ecletica-1594	82	12	’	'	PUNCT
ecletica-1594	82	13	and	and	CCONJ
ecletica-1594	82	14	hydrophobic	hydrophobic	NOUN
ecletica-1594	82	15	interactions	interaction	NOUN
ecletica-1594	82	16	with	with	ADP
ecletica-1594	82	17	arg'60	arg'60	PROPN
ecletica-1594	82	18	,	,	PUNCT
ecletica-1594	82	19	tyr'67	tyr'67	ADV
ecletica-1594	82	20	,	,	PUNCT
ecletica-1594	82	21	ile'66	ile'66	NOUN
ecletica-1594	82	22	,	,	PUNCT
ecletica-1594	82	23	and	and	CCONJ
ecletica-1594	82	24	lys'43	lys'43	X
ecletica-1594	82	25	.	.	PUNCT
ecletica-1594	83	1	furthermore	furthermore	ADV
ecletica-1594	83	2	,	,	PUNCT
ecletica-1594	83	3	5ad	5ad	NOUN
ecletica-1594	83	4	with	with	ADP
ecletica-1594	83	5	a	a	DET
ecletica-1594	83	6	binding	bind	VERB
ecletica-1594	83	7	affinity	affinity	NOUN
ecletica-1594	83	8	of	of	ADP
ecletica-1594	83	9	-26.4	-26.4	PROPN
ecletica-1594	83	10	kj	kj	PROPN
ecletica-1594	83	11	/	/	SYM
ecletica-1594	83	12	mol	mol	PROPN
ecletica-1594	83	13	is	be	AUX
ecletica-1594	83	14	hydrogen	hydrogen	NOUN
ecletica-1594	83	15	-	-	PUNCT
ecletica-1594	83	16	bonded	bond	VERB
ecletica-1594	83	17	with	with	ADP
ecletica-1594	83	18	tyr'59	tyr'59	PRON
ecletica-1594	83	19	arg'46	arg'46	NOUN
ecletica-1594	83	20	and	and	CCONJ
ecletica-1594	83	21	tyr'69	tyr'69	NOUN
ecletica-1594	83	22	and	and	CCONJ
ecletica-1594	83	23	shows	show	VERB
ecletica-1594	83	24	hydrophobic	hydrophobic	NOUN
ecletica-1594	83	25	interactions	interaction	NOUN
ecletica-1594	83	26	with	with	ADP
ecletica-1594	83	27	arg'60	arg'60	PUNCT
ecletica-1594	83	28	tyr'69	tyr'69	NOUN
ecletica-1594	83	29	and	and	CCONJ
ecletica-1594	83	30	arg'46	arg'46	NOUN
ecletica-1594	83	31	,	,	PUNCT
ecletica-1594	83	32	while	while	SCONJ
ecletica-1594	83	33	nam	nam	NOUN
ecletica-1594	83	34	with	with	ADP
ecletica-1594	83	35	a	a	DET
ecletica-1594	83	36	binding	bind	VERB
ecletica-1594	83	37	affinity	affinity	NOUN
ecletica-1594	83	38	of	of	ADP
ecletica-1594	83	39	–	–	PUNCT
ecletica-1594	83	40	17.2	17.2	NUM
ecletica-1594	83	41	kj	kj	PROPN
ecletica-1594	83	42	/	/	SYM
ecletica-1594	83	43	mol	mol	PROPN
ecletica-1594	83	44	displayed	display	VERB
ecletica-1594	83	45	hydrophobic	hydrophobic	NOUN
ecletica-1594	83	46	interactions	interaction	NOUN
ecletica-1594	83	47	with	with	ADP
ecletica-1594	83	48	lys'43	lys'43	NUM
ecletica-1594	83	49	arg'46	arg'46	NOUN
ecletica-1594	83	50	and	and	CCONJ
ecletica-1594	83	51	tyr'67	tyr'67	PROPN
ecletica-1594	83	52	.	.	PUNCT
ecletica-1594	84	1	penicillin	penicillin	PROPN
ecletica-1594	84	2	,	,	PUNCT
ecletica-1594	84	3	which	which	PRON
ecletica-1594	84	4	was	be	AUX
ecletica-1594	84	5	used	use	VERB
ecletica-1594	84	6	as	as	ADP
ecletica-1594	84	7	the	the	DET
ecletica-1594	84	8	standard	standard	ADJ
ecletica-1594	84	9	drug	drug	NOUN
ecletica-1594	84	10	,	,	PUNCT
ecletica-1594	84	11	has	have	VERB
ecletica-1594	84	12	a	a	DET
ecletica-1594	84	13	binding	bind	VERB
ecletica-1594	84	14	energy	energy	NOUN
ecletica-1594	84	15	of	of	ADP
ecletica-1594	84	16	–	–	PUNCT
ecletica-1594	84	17	25.1	25.1	NUM
ecletica-1594	84	18	kj	kj	PROPN
ecletica-1594	84	19	/	/	SYM
ecletica-1594	84	20	mol	mol	PROPN
ecletica-1594	84	21	,	,	PUNCT
ecletica-1594	84	22	interacting	interact	VERB
ecletica-1594	84	23	hydrophobically	hydrophobically	ADV
ecletica-1594	84	24	with	with	ADP
ecletica-1594	84	25	ala'83	ala'83	NOUN
ecletica-1594	84	26	asn'17	asn'17	PROPN
ecletica-1594	84	27	and	and	CCONJ
ecletica-1594	84	28	phe'86	phe'86	NUM
ecletica-1594	84	29	.	.	PUNCT
ecletica-1594	85	1	the	the	DET
ecletica-1594	85	2	ionization	ionization	NOUN
ecletica-1594	85	3	energy	energy	NOUN
ecletica-1594	85	4	(	(	PUNCT
ecletica-1594	85	5	ip	ip	NOUN
ecletica-1594	85	6	=	=	SYM
ecletica-1594	85	7	–	–	PUNCT
ecletica-1594	85	8	ehomo	ehomo	ADJ
ecletica-1594	85	9	)	)	PUNCT
ecletica-1594	85	10	and	and	CCONJ
ecletica-1594	85	11	electron	electron	NOUN
ecletica-1594	85	12	affinity	affinity	NOUN
ecletica-1594	85	13	(	(	PUNCT
ecletica-1594	85	14	ea	ea	NOUN
ecletica-1594	85	15	=	=	PUNCT
ecletica-1594	85	16	–	–	PUNCT
ecletica-1594	85	17	elumo	elumo	ADJ
ecletica-1594	85	18	)	)	PUNCT
ecletica-1594	85	19	estimated	estimate	VERB
ecletica-1594	85	20	from	from	ADP
ecletica-1594	85	21	the	the	DET
ecletica-1594	85	22	dft	dft	PROPN
ecletica-1594	85	23	calculations	calculation	NOUN
ecletica-1594	85	24	showed	show	VERB
ecletica-1594	85	25	that	that	SCONJ
ecletica-1594	85	26	nal	nal	NOUN
ecletica-1594	85	27	has	have	VERB
ecletica-1594	85	28	highest	high	ADJ
ecletica-1594	85	29	values	value	NOUN
ecletica-1594	85	30	for	for	ADP
ecletica-1594	85	31	both	both	PRON
ecletica-1594	85	32	ip	ip	NOUN
ecletica-1594	85	33	(	(	PUNCT
ecletica-1594	85	34	6.47	6.47	NUM
ecletica-1594	85	35	ev	ev	NOUN
ecletica-1594	85	36	)	)	PUNCT
ecletica-1594	85	37	and	and	CCONJ
ecletica-1594	85	38	ea	ea	X
ecletica-1594	85	39	(	(	PUNCT
ecletica-1594	85	40	4.01	4.01	NUM
ecletica-1594	85	41	ev	ev	NOUN
ecletica-1594	85	42	)	)	PUNCT
ecletica-1594	85	43	which	which	PRON
ecletica-1594	85	44	led	lead	VERB
ecletica-1594	85	45	to	to	ADP
ecletica-1594	85	46	lower	lower	VERB
ecletica-1594	85	47	energy	energy	NOUN
ecletica-1594	85	48	gap	gap	NOUN
ecletica-1594	85	49	;	;	PUNCT
ecletica-1594	85	50	thus	thus	ADV
ecletica-1594	85	51	,	,	PUNCT
ecletica-1594	85	52	supported	support	VERB
ecletica-1594	85	53	quick	quick	ADJ
ecletica-1594	85	54	electrons	electron	NOUN
ecletica-1594	85	55	transition	transition	NOUN
ecletica-1594	85	56	and	and	CCONJ
ecletica-1594	85	57	donation	donation	NOUN
ecletica-1594	85	58	to	to	ADP
ecletica-1594	85	59	the	the	DET
ecletica-1594	85	60	receptor	receptor	NOUN
ecletica-1594	85	61	than	than	ADP
ecletica-1594	85	62	other	other	ADJ
ecletica-1594	85	63	compounds	compound	NOUN
ecletica-1594	85	64	.	.	PUNCT
ecletica-1594	86	1	therefore	therefore	ADV
ecletica-1594	86	2	,	,	PUNCT
ecletica-1594	86	3	nal	nal	ADJ
ecletica-1594	86	4	,	,	PUNCT
ecletica-1594	86	5	nah	nah	INTJ
ecletica-1594	86	6	,	,	PUNCT
ecletica-1594	86	7	nai	nai	PROPN
ecletica-1594	86	8	and	and	CCONJ
ecletica-1594	86	9	naj	naj	PROPN
ecletica-1594	86	10	exhibited	exhibit	VERB
ecletica-1594	86	11	the	the	DET
ecletica-1594	86	12	most	most	ADV
ecletica-1594	86	13	significant	significant	ADJ
ecletica-1594	86	14	inhibitory	inhibitory	ADJ
ecletica-1594	86	15	potential	potential	NOUN
ecletica-1594	86	16	against	against	ADP
ecletica-1594	86	17	1xsd	1xsd	NUM
ecletica-1594	86	18	when	when	SCONJ
ecletica-1594	86	19	compared	compare	VERB
ecletica-1594	86	20	with	with	ADP
ecletica-1594	86	21	the	the	DET
ecletica-1594	86	22	standard	standard	ADJ
ecletica-1594	86	23	drug	drug	NOUN
ecletica-1594	86	24	(	(	PUNCT
ecletica-1594	86	25	penicillin	penicillin	NOUN
ecletica-1594	86	26	)	)	PUNCT
ecletica-1594	86	27	.	.	PUNCT
ecletica-1594	87	1	table	table	NOUN
ecletica-1594	87	2	2	2	NUM
ecletica-1594	87	3	.	.	PUNCT
ecletica-1594	87	4	binding	bind	VERB
ecletica-1594	87	5	affinity	affinity	NOUN
ecletica-1594	87	6	and	and	CCONJ
ecletica-1594	87	7	non	non	ADJ
ecletica-1594	87	8	-	-	ADJ
ecletica-1594	87	9	bonding	bonding	ADJ
ecletica-1594	87	10	interactions	interaction	NOUN
ecletica-1594	87	11	of	of	ADP
ecletica-1594	87	12	1xsd	1xsd	NUM
ecletica-1594	87	13	and	and	CCONJ
ecletica-1594	87	14	4wk3	4wk3	NUM
ecletica-1594	87	15	receptors	receptor	NOUN
ecletica-1594	87	16	with	with	ADP
ecletica-1594	87	17	ligands	ligand	NOUN
ecletica-1594	87	18	.	.	PUNCT
ecletica-1594	88	1	ligand	ligand	VERB
ecletica-1594	88	2	1xsd	1xsd	NUM
ecletica-1594	88	3	4wk3	4wk3	NUM
ecletica-1594	88	4	binding	bind	VERB
ecletica-1594	88	5	affinity	affinity	NOUN
ecletica-1594	88	6	δg	δg	ADP
ecletica-1594	88	7	(	(	PUNCT
ecletica-1594	88	8	kj	kj	PROPN
ecletica-1594	88	9	/	/	SYM
ecletica-1594	88	10	mol	mol	NOUN
ecletica-1594	88	11	)	)	PUNCT
ecletica-1594	88	12	binding	bind	VERB
ecletica-1594	88	13	affinity	affinity	NOUN
ecletica-1594	88	14	δg	δg	ADP
ecletica-1594	88	15	(	(	PUNCT
ecletica-1594	88	16	kj	kj	PROPN
ecletica-1594	88	17	/	/	SYM
ecletica-1594	88	18	mol	mol	PROPN
ecletica-1594	88	19	)	)	PUNCT
ecletica-1594	88	20	nah	nah	INTJ
ecletica-1594	88	21	–	–	PUNCT
ecletica-1594	88	22	26.4	26.4	NUM
ecletica-1594	88	23	–	–	PUNCT
ecletica-1594	88	24	24.3	24.3	NUM
ecletica-1594	88	25	nai	nai	NOUN
ecletica-1594	88	26	–	–	PUNCT
ecletica-1594	88	27	27.6	27.6	NUM
ecletica-1594	88	28	–	–	SYM
ecletica-1594	88	29	24.7	24.7	NUM
ecletica-1594	88	30	naj	naj	NOUN
ecletica-1594	88	31	–	–	PUNCT
ecletica-1594	88	32	28.5	28.5	NUM
ecletica-1594	88	33	–	–	SYM
ecletica-1594	88	34	25.1	25.1	NUM
ecletica-1594	88	35	nak	nak	NOUN
ecletica-1594	88	36	–	–	PUNCT
ecletica-1594	88	37	26.8	26.8	NUM
ecletica-1594	88	38	–	–	PUNCT
ecletica-1594	88	39	25.5	25.5	NUM
ecletica-1594	88	40	nal	nal	NOUN
ecletica-1594	88	41	–	–	PUNCT
ecletica-1594	88	42	27.2	27.2	NUM
ecletica-1594	88	43	–	–	PUNCT
ecletica-1594	88	44	24.3	24.3	NUM
ecletica-1594	88	45	nam	nam	NOUN
ecletica-1594	88	46	–	–	PUNCT
ecletica-1594	88	47	25.9	25.9	NUM
ecletica-1594	88	48	–	–	PUNCT
ecletica-1594	88	49	28.0	28.0	NUM
ecletica-1594	88	50	nan	nan	NOUN
ecletica-1594	88	51	–	–	PUNCT
ecletica-1594	88	52	23.8	23.8	NUM
ecletica-1594	88	53	–	–	PUNCT
ecletica-1594	88	54	28.0	28.0	NUM
ecletica-1594	88	55	5ad	5ad	NOUN
ecletica-1594	88	56	–	–	PUNCT
ecletica-1594	88	57	24.3	24.3	NUM
ecletica-1594	88	58	–	–	PUNCT
ecletica-1594	88	59	23.0	23.0	NUM
ecletica-1594	88	60	penicillin	penicillin	NOUN
ecletica-1594	88	61	–	–	PUNCT
ecletica-1594	88	62	26.4	26.4	NUM
ecletica-1594	88	63	–	–	SYM
ecletica-1594	88	64	22.6	22.6	NUM
ecletica-1594	88	65	sulfamethoxazole	sulfamethoxazole	NOUN
ecletica-1594	88	66	–	–	PUNCT
ecletica-1594	88	67	23.4	23.4	NUM
ecletica-1594	88	68	–	–	SYM
ecletica-1594	88	69	22.6	22.6	NUM
ecletica-1594	88	70	source	source	NOUN
ecletica-1594	88	71	:	:	PUNCT
ecletica-1594	88	72	elaborated	elaborate	VERB
ecletica-1594	88	73	by	by	ADP
ecletica-1594	88	74	the	the	DET
ecletica-1594	88	75	authors	author	NOUN
ecletica-1594	88	76	.	.	PUNCT
ecletica-1594	89	1	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	X
ecletica-1594	89	2	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	X
ecletica-1594	89	3	original	original	ADJ
ecletica-1594	89	4	article	article	NOUN
ecletica-1594	89	5	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	X
ecletica-1594	89	6	issn	issn	VERB
ecletica-1594	89	7	1678	1678	NUM
ecletica-1594	89	8	-	-	SYM
ecletica-1594	89	9	4618	4618	NUM
ecletica-1594	89	10	page	page	NOUN
ecletica-1594	89	11	5/14	5/14	NUM
ecletica-1594	89	12	2d	2d	NUM
ecletica-1594	89	13	structure	structure	NOUN
ecletica-1594	89	14	3d	3d	NUM
ecletica-1594	89	15	structure	structure	NOUN
ecletica-1594	89	16	1xsd	1xsd	PROPN
ecletica-1594	90	1	+	+	CCONJ
ecletica-1594	90	2	nah	nah	INTJ
ecletica-1594	90	3	1xsd	1xsd	PROPN
ecletica-1594	90	4	+	+	CCONJ
ecletica-1594	90	5	nai	nai	VERB
ecletica-1594	90	6	1xsd	1xsd	PROPN
ecletica-1594	90	7	+	+	CCONJ
ecletica-1594	90	8	naj	naj	X
ecletica-1594	90	9	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	X
ecletica-1594	90	10	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	X
ecletica-1594	90	11	original	original	ADJ
ecletica-1594	90	12	article	article	NOUN
ecletica-1594	90	13	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	X
ecletica-1594	90	14	issn	issn	VERB
ecletica-1594	90	15	1678	1678	NUM
ecletica-1594	90	16	-	-	SYM
ecletica-1594	90	17	4618	4618	NUM
ecletica-1594	90	18	page	page	NOUN
ecletica-1594	90	19	6/14	6/14	NUM
ecletica-1594	90	20	1xsd	1xsd	PROPN
ecletica-1594	90	21	+	+	NUM
ecletica-1594	90	22	nak	nak	PROPN
ecletica-1594	90	23	1xsd	1xsd	NOUN
ecletica-1594	90	24	+	+	CCONJ
ecletica-1594	90	25	nal	nal	ADJ
ecletica-1594	90	26	1xsd	1xsd	PROPN
ecletica-1594	90	27	+	+	NOUN
ecletica-1594	90	28	nam	nam	NOUN
ecletica-1594	90	29	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	X
ecletica-1594	90	30	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	X
ecletica-1594	90	31	original	original	ADJ
ecletica-1594	90	32	article	article	NOUN
ecletica-1594	90	33	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	X
ecletica-1594	90	34	issn	issn	VERB
ecletica-1594	90	35	1678	1678	NUM
ecletica-1594	90	36	-	-	SYM
ecletica-1594	90	37	4618	4618	NUM
ecletica-1594	90	38	page	page	NOUN
ecletica-1594	90	39	7/14	7/14	NUM
ecletica-1594	90	40	1xsd	1xsd	PROPN
ecletica-1594	91	1	+	+	PROPN
ecletica-1594	91	2	nan	nan	PROPN
ecletica-1594	91	3	1xsd+	1xsd+	PROPN
ecletica-1594	91	4	5ad	5ad	ADJ
ecletica-1594	91	5	1xsd	1xsd	PROPN
ecletica-1594	91	6	+	+	CCONJ
ecletica-1594	91	7	penicillin	penicillin	NOUN
ecletica-1594	91	8	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	X
ecletica-1594	91	9	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	X
ecletica-1594	91	10	original	original	ADJ
ecletica-1594	91	11	article	article	NOUN
ecletica-1594	91	12	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	X
ecletica-1594	91	13	issn	issn	VERB
ecletica-1594	91	14	1678	1678	NUM
ecletica-1594	91	15	-	-	SYM
ecletica-1594	91	16	4618	4618	NUM
ecletica-1594	91	17	page	page	NOUN
ecletica-1594	91	18	8/14	8/14	NUM
ecletica-1594	91	19	1xsd	1xsd	PRON
ecletica-1594	91	20	+	+	CCONJ
ecletica-1594	91	21	sulfonamide	sulfonamide	ADJ
ecletica-1594	91	22	figure	figure	NOUN
ecletica-1594	91	23	2	2	NUM
ecletica-1594	91	24	.	.	X
ecletica-1594	91	25	2d	2d	NOUN
ecletica-1594	91	26	and	and	CCONJ
ecletica-1594	91	27	3d	3d	NUM
ecletica-1594	91	28	of	of	ADP
ecletica-1594	91	29	1xsd	1xsd	NUM
ecletica-1594	91	30	with	with	ADP
ecletica-1594	91	31	the	the	DET
ecletica-1594	91	32	sulfamidophosphonates	sulfamidophosphonate	NOUN
ecletica-1594	91	33	showing	show	VERB
ecletica-1594	91	34	hydrogen	hydrogen	NOUN
ecletica-1594	91	35	interactions	interaction	NOUN
ecletica-1594	91	36	.	.	PUNCT
ecletica-1594	92	1	source	source	NOUN
ecletica-1594	92	2	:	:	PUNCT
ecletica-1594	92	3	elaborated	elaborate	VERB
ecletica-1594	92	4	by	by	ADP
ecletica-1594	92	5	the	the	DET
ecletica-1594	92	6	authors	author	NOUN
ecletica-1594	92	7	.	.	PUNCT
ecletica-1594	93	1	the	the	DET
ecletica-1594	93	2	calculated	calculated	ADJ
ecletica-1594	93	3	binding	bind	VERB
ecletica-1594	93	4	affinities	affinity	NOUN
ecletica-1594	93	5	for	for	ADP
ecletica-1594	93	6	the	the	DET
ecletica-1594	93	7	ligands	ligand	NOUN
ecletica-1594	93	8	with	with	ADP
ecletica-1594	93	9	4wk3	4wk3	NUM
ecletica-1594	93	10	receptor	receptor	NOUN
ecletica-1594	93	11	showed	show	VERB
ecletica-1594	93	12	that	that	SCONJ
ecletica-1594	93	13	the	the	DET
ecletica-1594	93	14	drugs	drug	NOUN
ecletica-1594	93	15	interacted	interact	VERB
ecletica-1594	93	16	with	with	ADP
ecletica-1594	93	17	4wk3	4wk3	NUM
ecletica-1594	93	18	,	,	PUNCT
ecletica-1594	93	19	the	the	DET
ecletica-1594	93	20	bacterial	bacterial	ADJ
ecletica-1594	93	21	secondary	secondary	ADJ
ecletica-1594	93	22	messenger	messenger	NOUN
ecletica-1594	93	23	involved	involve	VERB
ecletica-1594	93	24	in	in	ADP
ecletica-1594	93	25	sensing	sense	VERB
ecletica-1594	93	26	integrity	integrity	NOUN
ecletica-1594	93	27	,	,	PUNCT
ecletica-1594	93	28	cell	cell	NOUN
ecletica-1594	93	29	wall	wall	NOUN
ecletica-1594	93	30	metabolism	metabolism	NOUN
ecletica-1594	93	31	and	and	CCONJ
ecletica-1594	93	32	potassium	potassium	NOUN
ecletica-1594	93	33	transport	transport	NOUN
ecletica-1594	93	34	.	.	PUNCT
ecletica-1594	94	1	the	the	DET
ecletica-1594	94	2	binding	bind	VERB
ecletica-1594	94	3	affinities	affinity	NOUN
ecletica-1594	94	4	from	from	ADP
ecletica-1594	94	5	the	the	DET
ecletica-1594	94	6	docking	docking	NOUN
ecletica-1594	94	7	results	result	NOUN
ecletica-1594	94	8	showed	show	VERB
ecletica-1594	94	9	that	that	SCONJ
ecletica-1594	94	10	nak	nak	PROPN
ecletica-1594	94	11	,	,	PUNCT
ecletica-1594	94	12	nan	nan	PROPN
ecletica-1594	94	13	,	,	PUNCT
ecletica-1594	94	14	5ad	5ad	PROPN
ecletica-1594	94	15	,	,	PUNCT
ecletica-1594	94	16	and	and	CCONJ
ecletica-1594	94	17	nah	nah	INTJ
ecletica-1594	94	18	presented	present	VERB
ecletica-1594	94	19	binding	bind	VERB
ecletica-1594	94	20	affinities	affinity	NOUN
ecletica-1594	94	21	of	of	ADP
ecletica-1594	94	22	–	–	PUNCT
ecletica-1594	94	23	23.0	23.0	NUM
ecletica-1594	94	24	,	,	PUNCT
ecletica-1594	94	25	–	–	PUNCT
ecletica-1594	94	26	24.3	24.3	NUM
ecletica-1594	94	27	,	,	PUNCT
ecletica-1594	94	28	–	–	PUNCT
ecletica-1594	94	29	25.1	25.1	NUM
ecletica-1594	94	30	,	,	PUNCT
ecletica-1594	94	31	and	and	CCONJ
ecletica-1594	94	32	–	–	PUNCT
ecletica-1594	94	33	25.5	25.5	NUM
ecletica-1594	94	34	kj	kj	PROPN
ecletica-1594	94	35	/	/	SYM
ecletica-1594	94	36	mol	mol	PROPN
ecletica-1594	94	37	,	,	PUNCT
ecletica-1594	94	38	respectively	respectively	ADV
ecletica-1594	94	39	.	.	PUNCT
ecletica-1594	95	1	additionally	additionally	ADV
ecletica-1594	95	2	,	,	PUNCT
ecletica-1594	95	3	nal	nal	NOUN
ecletica-1594	95	4	,	,	PUNCT
ecletica-1594	95	5	naj	naj	NOUN
ecletica-1594	95	6	,	,	PUNCT
ecletica-1594	95	7	nai	nai	PROPN
ecletica-1594	95	8	,	,	PUNCT
ecletica-1594	95	9	and	and	CCONJ
ecletica-1594	95	10	nam	nam	NOUN
ecletica-1594	95	11	bind	bind	VERB
ecletica-1594	95	12	to	to	ADP
ecletica-1594	95	13	4wk3	4wk3	NUM
ecletica-1594	95	14	receptors	receptor	NOUN
ecletica-1594	95	15	with	with	ADP
ecletica-1594	95	16	affinities	affinity	NOUN
ecletica-1594	95	17	of	of	ADP
ecletica-1594	95	18	–	–	PUNCT
ecletica-1594	95	19	25.5	25.5	NUM
ecletica-1594	95	20	,	,	PUNCT
ecletica-1594	95	21	–	–	PUNCT
ecletica-1594	95	22	25.9	25.9	NUM
ecletica-1594	95	23	,	,	PUNCT
ecletica-1594	95	24	–	–	PUNCT
ecletica-1594	95	25	27.6	27.6	NUM
ecletica-1594	95	26	,	,	PUNCT
ecletica-1594	95	27	and	and	CCONJ
ecletica-1594	95	28	–	–	PUNCT
ecletica-1594	95	29	28.0	28.0	NUM
ecletica-1594	95	30	kj	kj	PROPN
ecletica-1594	95	31	/	/	SYM
ecletica-1594	95	32	mol	mol	PROPN
ecletica-1594	95	33	,	,	PUNCT
ecletica-1594	95	34	respectively	respectively	ADV
ecletica-1594	95	35	(	(	PUNCT
ecletica-1594	95	36	table	table	NOUN
ecletica-1594	95	37	2	2	NUM
ecletica-1594	95	38	)	)	PUNCT
ecletica-1594	95	39	.	.	PUNCT
ecletica-1594	96	1	the	the	DET
ecletica-1594	96	2	h	h	NOUN
ecletica-1594	96	3	-	-	PUNCT
ecletica-1594	96	4	bond	bond	NOUN
ecletica-1594	96	5	formed	form	VERB
ecletica-1594	96	6	between	between	ADP
ecletica-1594	96	7	4wk3	4wk3	NUM
ecletica-1594	96	8	receptor	receptor	NOUN
ecletica-1594	96	9	amino	amino	NOUN
ecletica-1594	96	10	acid	acid	NOUN
ecletica-1594	96	11	residues	residue	NOUN
ecletica-1594	96	12	and	and	CCONJ
ecletica-1594	96	13	the	the	DET
ecletica-1594	96	14	drugs	drug	NOUN
ecletica-1594	96	15	is	be	AUX
ecletica-1594	96	16	within	within	ADP
ecletica-1594	96	17	3.5	3.5	NUM
ecletica-1594	96	18	å	å	NOUN
ecletica-1594	96	19	.	.	PUNCT
ecletica-1594	97	1	other	other	ADJ
ecletica-1594	97	2	hydrophobic	hydrophobic	NOUN
ecletica-1594	97	3	interactions	interaction	NOUN
ecletica-1594	97	4	of	of	ADP
ecletica-1594	97	5	the	the	DET
ecletica-1594	97	6	medications	medication	NOUN
ecletica-1594	97	7	with	with	ADP
ecletica-1594	97	8	4wk3	4wk3	NUM
ecletica-1594	97	9	are	be	AUX
ecletica-1594	97	10	displayed	display	VERB
ecletica-1594	97	11	in	in	ADP
ecletica-1594	97	12	fig	fig	NOUN
ecletica-1594	97	13	.	.	PUNCT
ecletica-1594	98	1	3	3	X
ecletica-1594	98	2	.	.	X
ecletica-1594	98	3	compound	compound	NOUN
ecletica-1594	98	4	nak	nak	PROPN
ecletica-1594	98	5	is	be	AUX
ecletica-1594	98	6	h	h	NOUN
ecletica-1594	98	7	-	-	PUNCT
ecletica-1594	98	8	bonded	bond	VERB
ecletica-1594	98	9	with	with	ADP
ecletica-1594	98	10	lys'29	lys'29	NUM
ecletica-1594	98	11	and	and	CCONJ
ecletica-1594	98	12	also	also	ADV
ecletica-1594	98	13	has	have	VERB
ecletica-1594	98	14	hydrophobic	hydrophobic	NOUN
ecletica-1594	98	15	interactions	interaction	NOUN
ecletica-1594	98	16	with	with	ADP
ecletica-1594	98	17	ala'17	ala'17	ADJ
ecletica-1594	98	18	,	,	PUNCT
ecletica-1594	98	19	val'21	val'21	NOUN
ecletica-1594	98	20	,	,	PUNCT
ecletica-1594	98	21	lys'29	lys'29	NOUN
ecletica-1594	98	22	and	and	CCONJ
ecletica-1594	98	23	thr'42	thr'42	VERB
ecletica-1594	98	24	;	;	PUNCT
ecletica-1594	98	25	naj	naj	X
ecletica-1594	98	26	is	be	AUX
ecletica-1594	98	27	hydrogen	hydrogen	NOUN
ecletica-1594	98	28	bonded	bond	VERB
ecletica-1594	98	29	with	with	ADP
ecletica-1594	98	30	asn'24	asn'24	ADP
ecletica-1594	98	31	,	,	PUNCT
ecletica-1594	98	32	gly'47	gly'47	PROPN
ecletica-1594	98	33	,	,	PUNCT
ecletica-1594	98	34	gln'108	gln'108	PROPN
ecletica-1594	98	35	,	,	PUNCT
ecletica-1594	98	36	arg'26	arg'26	NUM
ecletica-1594	98	37	,	,	PUNCT
ecletica-1594	98	38	and	and	CCONJ
ecletica-1594	98	39	formed	form	VERB
ecletica-1594	98	40	hydrophobic	hydrophobic	NOUN
ecletica-1594	98	41	interactions	interaction	NOUN
ecletica-1594	98	42	with	with	ADP
ecletica-1594	98	43	arg'26	arg'26	PROPN
ecletica-1594	98	44	,	,	PUNCT
ecletica-1594	98	45	gln'108	gln'108	PROPN
ecletica-1594	98	46	,	,	PUNCT
ecletica-1594	98	47	gly'47	gly'47	PROPN
ecletica-1594	98	48	,	,	PUNCT
ecletica-1594	98	49	val'48	val'48	NOUN
ecletica-1594	98	50	,	,	PUNCT
ecletica-1594	98	51	arg'26	arg'26	PUNCT
ecletica-1594	98	52	and	and	CCONJ
ecletica-1594	98	53	arg'52	arg'52	NUM
ecletica-1594	98	54	;	;	PUNCT
ecletica-1594	98	55	nan	nan	PROPN
ecletica-1594	98	56	showed	show	VERB
ecletica-1594	98	57	h	h	NOUN
ecletica-1594	98	58	-	-	PUNCT
ecletica-1594	98	59	bond	bond	NOUN
ecletica-1594	98	60	interactions	interaction	NOUN
ecletica-1594	98	61	with	with	ADP
ecletica-1594	98	62	asp'10	asp'10	NUM
ecletica-1594	98	63	thr'42	thr'42	PUNCT
ecletica-1594	98	64	and	and	CCONJ
ecletica-1594	98	65	lys'29	lys'29	NOUN
ecletica-1594	98	66	,	,	PUNCT
ecletica-1594	98	67	hydrophobic	hydrophobic	NOUN
ecletica-1594	98	68	interactions	interaction	NOUN
ecletica-1594	98	69	with	with	ADP
ecletica-1594	98	70	ser'13	ser'13	ADJ
ecletica-1594	98	71	lys'29	lys'29	NOUN
ecletica-1594	98	72	and	and	CCONJ
ecletica-1594	98	73	thr'42	thr'42	VERB
ecletica-1594	98	74	;	;	PUNCT
ecletica-1594	98	75	5ad	5ad	NOUN
ecletica-1594	98	76	is	be	AUX
ecletica-1594	98	77	h	h	NOUN
ecletica-1594	98	78	-	-	PUNCT
ecletica-1594	98	79	bonded	bond	VERB
ecletica-1594	98	80	with	with	ADP
ecletica-1594	98	81	arg'26	arg'26	PROPN
ecletica-1594	98	82	gly'47	gly'47	PROPN
ecletica-1594	98	83	arg'26	arg'26	PUNCT
ecletica-1594	98	84	asn'24	asn'24	PUNCT
ecletica-1594	98	85	arg'26	arg'26	PUNCT
ecletica-1594	98	86	and	and	CCONJ
ecletica-1594	98	87	arg'52	arg'52	NUM
ecletica-1594	98	88	and	and	CCONJ
ecletica-1594	98	89	also	also	ADV
ecletica-1594	98	90	has	have	VERB
ecletica-1594	98	91	hydrophobic	hydrophobic	NOUN
ecletica-1594	98	92	interactions	interaction	NOUN
ecletica-1594	98	93	with	with	ADP
ecletica-1594	98	94	cys'46	cys'46	NOUN
ecletica-1594	98	95	arg'26	arg'26	PUNCT
ecletica-1594	98	96	arg'52	arg'52	NUM
ecletica-1594	98	97	,	,	PUNCT
ecletica-1594	98	98	gln'47	gln'47	PROPN
ecletica-1594	98	99	and	and	CCONJ
ecletica-1594	98	100	arg'26	arg'26	NUM
ecletica-1594	98	101	;	;	PUNCT
ecletica-1594	98	102	nah	nah	CCONJ
ecletica-1594	98	103	showed	show	VERB
ecletica-1594	98	104	hydrophobic	hydrophobic	NOUN
ecletica-1594	98	105	interactions	interaction	NOUN
ecletica-1594	98	106	with	with	ADP
ecletica-1594	98	107	gln'14	gln'14	PROPN
ecletica-1594	98	108	lys'29	lys'29	PROPN
ecletica-1594	98	109	ser'13	ser'13	VERB
ecletica-1594	98	110	and	and	CCONJ
ecletica-1594	98	111	thr'42	thr'42	ADP
ecletica-1594	98	112	;	;	PUNCT
ecletica-1594	98	113	nal	nal	ADJ
ecletica-1594	98	114	arg'26	arg'26	PUNCT
ecletica-1594	98	115	met'1	met'1	PROPN
ecletica-1594	98	116	phe'106	phe'106	NOUN
ecletica-1594	98	117	gln'108	gln'108	VERB
ecletica-1594	98	118	gly'47	gly'47	PROPN
ecletica-1594	98	119	asn'49	asn'49	PRON
ecletica-1594	98	120	and	and	CCONJ
ecletica-1594	98	121	val'48	val'48	NUM
ecletica-1594	98	122	;	;	PUNCT
ecletica-1594	98	123	nai	nai	PROPN
ecletica-1594	98	124	showed	show	VERB
ecletica-1594	98	125	hydrophobic	hydrophobic	NOUN
ecletica-1594	98	126	interactions	interaction	NOUN
ecletica-1594	98	127	with	with	ADP
ecletica-1594	98	128	thr'42	thr'42	PRON
ecletica-1594	98	129	gln'14	gln'14	PROPN
ecletica-1594	98	130	ser'13	ser'13	VERB
ecletica-1594	98	131	and	and	CCONJ
ecletica-1594	98	132	lys'29	lys'29	NUM
ecletica-1594	98	133	;	;	PUNCT
ecletica-1594	98	134	nam	nam	NOUN
ecletica-1594	98	135	showed	show	VERB
ecletica-1594	98	136	hydrophobic	hydrophobic	NOUN
ecletica-1594	98	137	interactions	interaction	NOUN
ecletica-1594	98	138	with	with	ADP
ecletica-1594	98	139	val'103	val'103	PROPN
ecletica-1594	98	140	phe'106	phe'106	PROPN
ecletica-1594	98	141	thr'28	thr'28	PRON
ecletica-1594	98	142	gly'47	gly'47	PROPN
ecletica-1594	98	143	and	and	CCONJ
ecletica-1594	98	144	arg'26	arg'26	NUM
ecletica-1594	98	145	;	;	PUNCT
ecletica-1594	98	146	whereas	whereas	SCONJ
ecletica-1594	98	147	penicillin	penicillin	NOUN
ecletica-1594	98	148	is	be	AUX
ecletica-1594	98	149	hbonded	hbonde	VERB
ecletica-1594	98	150	to	to	PART
ecletica-1594	98	151	asn'61	asn'61	ADP
ecletica-1594	98	152	asn'66	asn'66	NOUN
ecletica-1594	98	153	and	and	CCONJ
ecletica-1594	98	154	ala'96	ala'96	NOUN
ecletica-1594	98	155	,	,	PUNCT
ecletica-1594	98	156	and	and	CCONJ
ecletica-1594	98	157	hydrophobically	hydrophobically	ADV
ecletica-1594	98	158	interacted	interact	VERB
ecletica-1594	98	159	with	with	ADP
ecletica-1594	98	160	asn'61	asn'61	NOUN
ecletica-1594	98	161	asn'66	asn'66	NOUN
ecletica-1594	98	162	and	and	CCONJ
ecletica-1594	98	163	ala'96	ala'96	NOUN
ecletica-1594	98	164	residues	residue	NOUN
ecletica-1594	98	165	(	(	PUNCT
ecletica-1594	98	166	fig	fig	NOUN
ecletica-1594	98	167	.	.	PUNCT
ecletica-1594	98	168	4	4	NUM
ecletica-1594	98	169	)	)	PUNCT
ecletica-1594	98	170	.	.	PUNCT
ecletica-1594	99	1	although	although	SCONJ
ecletica-1594	99	2	no	no	DET
ecletica-1594	99	3	direct	direct	ADJ
ecletica-1594	99	4	relationship	relationship	NOUN
ecletica-1594	99	5	is	be	AUX
ecletica-1594	99	6	observed	observe	VERB
ecletica-1594	99	7	between	between	ADP
ecletica-1594	99	8	the	the	DET
ecletica-1594	99	9	frontier	frontier	NOUN
ecletica-1594	99	10	energies	energy	NOUN
ecletica-1594	99	11	of	of	ADP
ecletica-1594	99	12	the	the	DET
ecletica-1594	99	13	ligands	ligand	NOUN
ecletica-1594	99	14	and	and	CCONJ
ecletica-1594	99	15	the	the	DET
ecletica-1594	99	16	binding	bind	VERB
ecletica-1594	99	17	affinities	affinity	NOUN
ecletica-1594	99	18	,	,	PUNCT
ecletica-1594	99	19	those	those	DET
ecletica-1594	99	20	ligands	ligand	NOUN
ecletica-1594	99	21	with	with	ADP
ecletica-1594	99	22	higher	high	ADJ
ecletica-1594	99	23	ip	ip	NOUN
ecletica-1594	99	24	presented	present	VERB
ecletica-1594	99	25	good	good	ADJ
ecletica-1594	99	26	binding	bind	VERB
ecletica-1594	99	27	affinities	affinity	NOUN
ecletica-1594	99	28	.	.	PUNCT
ecletica-1594	100	1	the	the	DET
ecletica-1594	100	2	results	result	NOUN
ecletica-1594	100	3	revealed	reveal	VERB
ecletica-1594	100	4	that	that	SCONJ
ecletica-1594	100	5	compounds	compound	VERB
ecletica-1594	100	6	nah	nah	INTJ
ecletica-1594	100	7	,	,	PUNCT
ecletica-1594	100	8	nal	nal	PROPN
ecletica-1594	100	9	,	,	PUNCT
ecletica-1594	100	10	nan	nan	PROPN
ecletica-1594	100	11	,	,	PUNCT
ecletica-1594	100	12	nai	nai	PROPN
ecletica-1594	100	13	,	,	PUNCT
ecletica-1594	100	14	naj	naj	PROPN
ecletica-1594	100	15	,	,	PUNCT
ecletica-1594	100	16	5ad	5ad	NOUN
ecletica-1594	100	17	and	and	CCONJ
ecletica-1594	100	18	nam	nam	NOUN
ecletica-1594	100	19	exhibited	exhibit	VERB
ecletica-1594	100	20	significant	significant	ADJ
ecletica-1594	100	21	inhibitions	inhibition	NOUN
ecletica-1594	100	22	against	against	ADP
ecletica-1594	100	23	4wk3	4wk3	NUM
ecletica-1594	100	24	when	when	SCONJ
ecletica-1594	100	25	compared	compare	VERB
ecletica-1594	100	26	with	with	ADP
ecletica-1594	100	27	the	the	DET
ecletica-1594	100	28	standard	standard	ADJ
ecletica-1594	100	29	drug	drug	NOUN
ecletica-1594	100	30	(	(	PUNCT
ecletica-1594	100	31	penicillin	penicillin	NOUN
ecletica-1594	100	32	)	)	PUNCT
ecletica-1594	100	33	.	.	PUNCT
ecletica-1594	101	1	complex	complex	ADJ
ecletica-1594	101	2	2d	2d	PROPN
ecletica-1594	101	3	3d	3d	NUM
ecletica-1594	101	4	4wk3	4wk3	NUM
ecletica-1594	102	1	+	+	ADJ
ecletica-1594	102	2	nah	nah	INTJ
ecletica-1594	102	3	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	X
ecletica-1594	102	4	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	X
ecletica-1594	102	5	original	original	ADJ
ecletica-1594	102	6	article	article	NOUN
ecletica-1594	102	7	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	X
ecletica-1594	102	8	issn	issn	VERB
ecletica-1594	102	9	1678	1678	NUM
ecletica-1594	102	10	-	-	SYM
ecletica-1594	102	11	4618	4618	NUM
ecletica-1594	102	12	page	page	NOUN
ecletica-1594	102	13	9/14	9/14	NUM
ecletica-1594	102	14	4wk3	4wk3	NUM
ecletica-1594	103	1	+	+	VERB
ecletica-1594	103	2	nai	nai	X
ecletica-1594	103	3	4wk3	4wk3	ADJ
ecletica-1594	103	4	+	+	ADJ
ecletica-1594	103	5	naj	naj	ADJ
ecletica-1594	103	6	4wk3	4wk3	NUM
ecletica-1594	103	7	+	+	NOUN
ecletica-1594	103	8	nak	nak	PROPN
ecletica-1594	103	9	4wk3	4wk3	NUM
ecletica-1594	103	10	+	+	ADJ
ecletica-1594	103	11	nal	nal	ADJ
ecletica-1594	103	12	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	X
ecletica-1594	103	13	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	X
ecletica-1594	103	14	original	original	ADJ
ecletica-1594	103	15	article	article	NOUN
ecletica-1594	103	16	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	X
ecletica-1594	103	17	issn	issn	VERB
ecletica-1594	103	18	1678	1678	NUM
ecletica-1594	103	19	-	-	SYM
ecletica-1594	103	20	4618	4618	NUM
ecletica-1594	103	21	page	page	NOUN
ecletica-1594	103	22	10/14	10/14	NUM
ecletica-1594	103	23	4wk3	4wk3	NUM
ecletica-1594	104	1	+	+	VERB
ecletica-1594	104	2	nam	nam	NOUN
ecletica-1594	104	3	4wk3	4wk3	NUM
ecletica-1594	105	1	+	+	ADJ
ecletica-1594	105	2	nan	nan	PROPN
ecletica-1594	105	3	4wk3	4wk3	NUM
ecletica-1594	105	4	+5ad	+5ad	X
ecletica-1594	105	5	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	X
ecletica-1594	105	6	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	X
ecletica-1594	105	7	original	original	ADJ
ecletica-1594	105	8	article	article	NOUN
ecletica-1594	105	9	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	X
ecletica-1594	105	10	issn	issn	VERB
ecletica-1594	105	11	1678	1678	NUM
ecletica-1594	105	12	-	-	SYM
ecletica-1594	105	13	4618	4618	NUM
ecletica-1594	105	14	page	page	NOUN
ecletica-1594	105	15	11/14	11/14	NUM
ecletica-1594	105	16	4wk3	4wk3	NUM
ecletica-1594	106	1	+	+	CCONJ
ecletica-1594	106	2	pencillin	pencillin	ADJ
ecletica-1594	106	3	4wk3	4wk3	NUM
ecletica-1594	106	4	+	+	CCONJ
ecletica-1594	106	5	sulfameth	sulfameth	PROPN
ecletica-1594	106	6	oxazole	oxazole	NOUN
ecletica-1594	106	7	figure	figure	NOUN
ecletica-1594	106	8	3	3	NUM
ecletica-1594	106	9	.	.	X
ecletica-1594	106	10	2d	2d	NOUN
ecletica-1594	106	11	and	and	CCONJ
ecletica-1594	106	12	3d	3d	NUM
ecletica-1594	106	13	of	of	ADP
ecletica-1594	106	14	4wk3	4wk3	NUM
ecletica-1594	106	15	with	with	ADP
ecletica-1594	106	16	sulfamidophosphonates	sulfamidophosphonate	NOUN
ecletica-1594	106	17	showing	show	VERB
ecletica-1594	106	18	hydrogen	hydrogen	NOUN
ecletica-1594	106	19	interactions	interaction	NOUN
ecletica-1594	106	20	.	.	PUNCT
ecletica-1594	107	1	source	source	NOUN
ecletica-1594	107	2	:	:	PUNCT
ecletica-1594	107	3	elaborated	elaborate	VERB
ecletica-1594	107	4	by	by	ADP
ecletica-1594	107	5	the	the	DET
ecletica-1594	107	6	authors	author	NOUN
ecletica-1594	107	7	.	.	PUNCT
ecletica-1594	108	1	3.3	3.3	NUM
ecletica-1594	108	2	.	.	PUNCT
ecletica-1594	109	1	molecular	molecular	ADJ
ecletica-1594	109	2	dynamics	dynamic	NOUN
ecletica-1594	109	3	simulation	simulation	NOUN
ecletica-1594	109	4	in	in	ADP
ecletica-1594	109	5	this	this	DET
ecletica-1594	109	6	study	study	NOUN
ecletica-1594	109	7	,	,	PUNCT
ecletica-1594	109	8	the	the	DET
ecletica-1594	109	9	root	root	NOUN
ecletica-1594	109	10	mean	mean	VERB
ecletica-1594	109	11	square	square	ADJ
ecletica-1594	109	12	deviation	deviation	NOUN
ecletica-1594	109	13	(	(	PUNCT
ecletica-1594	109	14	rmsd	rmsd	NOUN
ecletica-1594	109	15	)	)	PUNCT
ecletica-1594	109	16	,	,	PUNCT
ecletica-1594	109	17	root	root	NOUN
ecletica-1594	109	18	mean	mean	VERB
ecletica-1594	109	19	square	square	ADJ
ecletica-1594	109	20	fluctuation	fluctuation	NOUN
ecletica-1594	109	21	(	(	PUNCT
ecletica-1594	109	22	rmsf	rmsf	NOUN
ecletica-1594	109	23	)	)	PUNCT
ecletica-1594	109	24	,	,	PUNCT
ecletica-1594	109	25	and	and	CCONJ
ecletica-1594	109	26	actual	actual	ADJ
ecletica-1594	109	27	binding	bind	VERB
ecletica-1594	109	28	energies	energy	NOUN
ecletica-1594	109	29	for	for	ADP
ecletica-1594	109	30	naj	naj	PROPN
ecletica-1594	109	31	,	,	PUNCT
ecletica-1594	109	32	nan	nan	PROPN
ecletica-1594	109	33	,	,	PUNCT
ecletica-1594	109	34	and	and	CCONJ
ecletica-1594	109	35	nam	nam	NOUN
ecletica-1594	109	36	,	,	PUNCT
ecletica-1594	109	37	as	as	ADV
ecletica-1594	109	38	well	well	ADV
ecletica-1594	109	39	as	as	ADP
ecletica-1594	109	40	the	the	DET
ecletica-1594	109	41	studied	studied	ADJ
ecletica-1594	109	42	drug	drug	NOUN
ecletica-1594	109	43	(	(	PUNCT
ecletica-1594	109	44	penicillin	penicillin	NOUN
ecletica-1594	109	45	)	)	PUNCT
ecletica-1594	109	46	,	,	PUNCT
ecletica-1594	109	47	were	be	AUX
ecletica-1594	109	48	investigated	investigate	VERB
ecletica-1594	109	49	and	and	CCONJ
ecletica-1594	109	50	reported	report	VERB
ecletica-1594	109	51	.	.	PUNCT
ecletica-1594	110	1	as	as	SCONJ
ecletica-1594	110	2	shown	show	VERB
ecletica-1594	110	3	in	in	ADP
ecletica-1594	110	4	table	table	NOUN
ecletica-1594	110	5	3	3	NUM
ecletica-1594	110	6	,	,	PUNCT
ecletica-1594	110	7	it	it	PRON
ecletica-1594	110	8	was	be	AUX
ecletica-1594	110	9	observed	observe	VERB
ecletica-1594	110	10	that	that	SCONJ
ecletica-1594	110	11	naj	naj	NOUN
ecletica-1594	110	12	proved	prove	VERB
ecletica-1594	110	13	to	to	PART
ecletica-1594	110	14	have	have	VERB
ecletica-1594	110	15	the	the	DET
ecletica-1594	110	16	highest	high	ADJ
ecletica-1594	110	17	strength	strength	NOUN
ecletica-1594	110	18	in	in	ADP
ecletica-1594	110	19	inhibiting	inhibit	VERB
ecletica-1594	110	20	blai	blai	NOUN
ecletica-1594	110	21	repressor	repressor	NOUN
ecletica-1594	110	22	(	(	PUNCT
ecletica-1594	110	23	1xsd	1xsd	NUM
ecletica-1594	110	24	)	)	PUNCT
ecletica-1594	110	25	than	than	ADP
ecletica-1594	110	26	the	the	DET
ecletica-1594	110	27	studied	study	VERB
ecletica-1594	110	28	reference	reference	NOUN
ecletica-1594	110	29	compound	compound	NOUN
ecletica-1594	110	30	.	.	PUNCT
ecletica-1594	111	1	additionally	additionally	ADV
ecletica-1594	111	2	,	,	PUNCT
ecletica-1594	111	3	the	the	DET
ecletica-1594	111	4	report	report	NOUN
ecletica-1594	111	5	in	in	ADP
ecletica-1594	111	6	table	table	NOUN
ecletica-1594	111	7	3	3	NUM
ecletica-1594	111	8	revealed	reveal	VERB
ecletica-1594	111	9	that	that	SCONJ
ecletica-1594	111	10	nam	nam	PROPN
ecletica-1594	111	11	has	have	VERB
ecletica-1594	111	12	the	the	DET
ecletica-1594	111	13	lowest	low	ADJ
ecletica-1594	111	14	inhibitory	inhibitory	ADJ
ecletica-1594	111	15	activity	activity	NOUN
ecletica-1594	111	16	compared	compare	VERB
ecletica-1594	111	17	to	to	ADP
ecletica-1594	111	18	nan	nan	PROPN
ecletica-1594	111	19	and	and	CCONJ
ecletica-1594	111	20	the	the	DET
ecletica-1594	111	21	reference	reference	NOUN
ecletica-1594	111	22	compounds	compound	VERB
ecletica-1594	111	23	.	.	PUNCT
ecletica-1594	112	1	more	more	ADV
ecletica-1594	112	2	so	so	ADV
ecletica-1594	112	3	,	,	PUNCT
ecletica-1594	112	4	nan	nan	PROPN
ecletica-1594	112	5	with	with	ADP
ecletica-1594	112	6	2.3	2.3	NUM
ecletica-1594	112	7	kj	kj	NOUN
ecletica-1594	112	8	/	/	SYM
ecletica-1594	112	9	mol	mol	PROPN
ecletica-1594	112	10	as	as	SCONJ
ecletica-1594	112	11	binding	bind	VERB
ecletica-1594	112	12	energy	energy	NOUN
ecletica-1594	112	13	is	be	AUX
ecletica-1594	112	14	expected	expect	VERB
ecletica-1594	112	15	to	to	PART
ecletica-1594	112	16	have	have	VERB
ecletica-1594	112	17	the	the	DET
ecletica-1594	112	18	highest	high	ADJ
ecletica-1594	112	19	capacity	capacity	NOUN
ecletica-1594	112	20	to	to	PART
ecletica-1594	112	21	inhibit	inhibit	VERB
ecletica-1594	112	22	staphyloccus	staphyloccus	NOUN
ecletica-1594	112	23	aureus	aureus	PROPN
ecletica-1594	112	24	psta	psta	PROPN
ecletica-1594	112	25	(	(	PUNCT
ecletica-1594	112	26	pdb	pdb	PROPN
ecletica-1594	112	27	i	i	PROPN
ecletica-1594	112	28	d	d	PROPN
ecletica-1594	112	29	:	:	PUNCT
ecletica-1594	112	30	4wk3	4wk3	NUM
ecletica-1594	112	31	)	)	PUNCT
ecletica-1594	112	32	than	than	ADP
ecletica-1594	112	33	nam	nam	PROPN
ecletica-1594	112	34	and	and	CCONJ
ecletica-1594	112	35	the	the	DET
ecletica-1594	112	36	reference	reference	NOUN
ecletica-1594	112	37	compound	compound	NOUN
ecletica-1594	112	38	.	.	PUNCT
ecletica-1594	113	1	in	in	ADP
ecletica-1594	113	2	this	this	DET
ecletica-1594	113	3	work	work	NOUN
ecletica-1594	113	4	,	,	PUNCT
ecletica-1594	113	5	the	the	DET
ecletica-1594	113	6	rmsd	rmsd	NOUN
ecletica-1594	113	7	for	for	ADP
ecletica-1594	113	8	naj-1xsd	naj-1xsd	PROPN
ecletica-1594	113	9	and	and	CCONJ
ecletica-1594	113	10	nan-4wk3	nan-4wk3	NOUN
ecletica-1594	113	11	is	be	AUX
ecletica-1594	113	12	presented	present	VERB
ecletica-1594	113	13	in	in	ADP
ecletica-1594	113	14	figs	fig	NOUN
ecletica-1594	113	15	.	.	PUNCT
ecletica-1594	114	1	4	4	NUM
ecletica-1594	114	2	and	and	CCONJ
ecletica-1594	114	3	5	5	NUM
ecletica-1594	114	4	.	.	PUNCT
ecletica-1594	114	5	as	as	SCONJ
ecletica-1594	114	6	shown	show	VERB
ecletica-1594	114	7	in	in	ADP
ecletica-1594	114	8	the	the	DET
ecletica-1594	114	9	exact	exact	ADJ
ecletica-1594	114	10	figures	figure	NOUN
ecletica-1594	114	11	,	,	PUNCT
ecletica-1594	114	12	the	the	DET
ecletica-1594	114	13	extent	extent	NOUN
ecletica-1594	114	14	of	of	ADP
ecletica-1594	114	15	deviation	deviation	NOUN
ecletica-1594	114	16	of	of	ADP
ecletica-1594	114	17	the	the	DET
ecletica-1594	114	18	studied	study	VERB
ecletica-1594	114	19	complex	complex	NOUN
ecletica-1594	114	20	from	from	ADP
ecletica-1594	114	21	its	its	PRON
ecletica-1594	114	22	initial	initial	ADJ
ecletica-1594	114	23	configuration	configuration	NOUN
ecletica-1594	114	24	bound	bind	VERB
ecletica-1594	114	25	to	to	ADP
ecletica-1594	114	26	the	the	DET
ecletica-1594	114	27	studied	study	VERB
ecletica-1594	114	28	receptor	receptor	NOUN
ecletica-1594	114	29	was	be	AUX
ecletica-1594	114	30	examined	examine	VERB
ecletica-1594	114	31	in	in	ADP
ecletica-1594	114	32	the	the	DET
ecletica-1594	114	33	calculated	calculate	VERB
ecletica-1594	114	34	rmsd	rmsd	NOUN
ecletica-1594	114	35	.	.	PUNCT
ecletica-1594	115	1	the	the	DET
ecletica-1594	115	2	simulated	simulate	VERB
ecletica-1594	115	3	system	system	NOUN
ecletica-1594	115	4	proved	prove	VERB
ecletica-1594	115	5	stable	stable	ADJ
ecletica-1594	115	6	in	in	ADP
ecletica-1594	115	7	the	the	DET
ecletica-1594	115	8	last	last	ADJ
ecletica-1594	115	9	five	five	NUM
ecletica-1594	115	10	ps	ps	NOUN
ecletica-1594	115	11	for	for	ADP
ecletica-1594	115	12	the	the	DET
ecletica-1594	115	13	two	two	NUM
ecletica-1594	115	14	selected	select	VERB
ecletica-1594	115	15	compounds	compound	NOUN
ecletica-1594	115	16	in	in	ADP
ecletica-1594	115	17	table	table	NOUN
ecletica-1594	115	18	3	3	NUM
ecletica-1594	115	19	.	.	PUNCT
ecletica-1594	115	20	table	table	NOUN
ecletica-1594	115	21	3	3	NUM
ecletica-1594	115	22	.	.	PUNCT
ecletica-1594	115	23	calculated	calculate	VERB
ecletica-1594	115	24	binding	bind	VERB
ecletica-1594	115	25	energies	energy	NOUN
ecletica-1594	115	26	for	for	ADP
ecletica-1594	115	27	naj-1xsd	naj-1xsd	PROPN
ecletica-1594	115	28	,	,	PUNCT
ecletica-1594	115	29	nam-4wk3	nam-4wk3	PROPN
ecletica-1594	115	30	and	and	CCONJ
ecletica-1594	115	31	nan-4wk3	nan-4wk3	NOUN
ecletica-1594	115	32	with	with	ADP
ecletica-1594	115	33	penicillin	penicillin	NOUN
ecletica-1594	115	34	-	-	PUNCT
ecletica-1594	115	35	receptor	receptor	NOUN
ecletica-1594	115	36	complexes	complex	NOUN
ecletica-1594	115	37	.	.	PUNCT
ecletica-1594	116	1	complexes	complex	NOUN
ecletica-1594	116	2	binding	bind	VERB
ecletica-1594	116	3	energy	energy	NOUN
ecletica-1594	116	4	components	component	NOUN
ecletica-1594	116	5	(	(	PUNCT
ecletica-1594	116	6	kj	kj	PROPN
ecletica-1594	116	7	/	/	SYM
ecletica-1594	116	8	mol	mol	NOUN
ecletica-1594	116	9	)	)	PUNCT
ecletica-1594	116	10	δevdw	δevdw	ADJ
ecletica-1594	116	11	δeele	δeele	PROPN
ecletica-1594	116	12	δggas	δggas	NOUN
ecletica-1594	116	13	δgsol	δgsol	ADV
ecletica-1594	116	14	δgbind	δgbind	VERB
ecletica-1594	116	15	naj-1xsd	naj-1xsd	PROPN
ecletica-1594	116	16	–	–	PUNCT
ecletica-1594	116	17	2.6±0.4	2.6±0.4	NUM
ecletica-1594	116	18	8±1	8±1	NUM
ecletica-1594	116	19	5±1	5±1	NUM
ecletica-1594	116	20	1.00±0.04	1.00±0.04	NOUN
ecletica-1594	116	21	6.0	6.0	NUM
ecletica-1594	116	22	±	±	NUM
ecletica-1594	116	23	1	1	NUM
ecletica-1594	116	24	penicillin-1xsd	penicillin-1xsd	NOUN
ecletica-1594	116	25	–	–	PUNCT
ecletica-1594	116	26	29±2	29±2	NOUN
ecletica-1594	116	27	–	–	PUNCT
ecletica-1594	116	28	32±8	32±8	NUM
ecletica-1594	116	29	–	–	PUNCT
ecletica-1594	116	30	61±6	61±6	NUM
ecletica-1594	116	31	79±9	79±9	NUM
ecletica-1594	116	32	18±3	18±3	NUM
ecletica-1594	116	33	nam-4wk3	nam-4wk3	NOUN
ecletica-1594	116	34	–	–	PUNCT
ecletica-1594	116	35	2.2±0.5	2.2±0.5	NUM
ecletica-1594	116	36	–	–	PUNCT
ecletica-1594	116	37	0.38±0.08	0.38±0.08	NOUN
ecletica-1594	116	38	–	–	PUNCT
ecletica-1594	116	39	0.38±0.08	0.38±0.08	NUM
ecletica-1594	116	40	3.5±0.3	3.5±0.3	NUM
ecletica-1594	116	41	3.1±0.4	3.1±0.4	NUM
ecletica-1594	116	42	nan-4wk3	nan-4wk3	NOUN
ecletica-1594	116	43	–	–	PUNCT
ecletica-1594	116	44	2.1±0.4	2.1±0.4	NUM
ecletica-1594	116	45	0.1±0.1	0.1±0.1	SYM
ecletica-1594	117	1	1	1	NUM
ecletica-1594	117	2	.	.	NOUN
ecletica-1594	117	3	0	0	NUM
ecletica-1594	118	1	±	±	NUM
ecletica-1594	118	2	0.1	0.1	NUM
ecletica-1594	118	3	0.9±0.3	0.9±0.3	NUM
ecletica-1594	118	4	2.3±0.3	2.3±0.3	NUM
ecletica-1594	118	5	penicillin-4wk3	penicillin-4wk3	NOUN
ecletica-1594	118	6	–	–	PUNCT
ecletica-1594	118	7	2.0±0.4	2.0±0.4	NUM
ecletica-1594	118	8	–	–	SYM
ecletica-1594	118	9	0.3±0.2	0.3±0.2	NUM
ecletica-1594	118	10	–	–	PUNCT
ecletica-1594	118	11	0.3±0.2	0.3±0.2	NUM
ecletica-1594	119	1	3±5	3±5	NUM
ecletica-1594	119	2	2.3±0.3	2.3±0.3	NUM
ecletica-1594	119	3	source	source	NOUN
ecletica-1594	119	4	:	:	PUNCT
ecletica-1594	119	5	elaborated	elaborate	VERB
ecletica-1594	119	6	by	by	ADP
ecletica-1594	119	7	the	the	DET
ecletica-1594	119	8	authors	author	NOUN
ecletica-1594	119	9	.	.	PUNCT
ecletica-1594	120	1	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	X
ecletica-1594	120	2	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	X
ecletica-1594	120	3	original	original	ADJ
ecletica-1594	120	4	article	article	NOUN
ecletica-1594	120	5	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	X
ecletica-1594	120	6	issn	issn	VERB
ecletica-1594	120	7	1678	1678	NUM
ecletica-1594	120	8	-	-	SYM
ecletica-1594	120	9	4618	4618	NUM
ecletica-1594	120	10	page	page	NOUN
ecletica-1594	120	11	12/14	12/14	NUM
ecletica-1594	120	12	figure	figure	NOUN
ecletica-1594	120	13	4	4	NUM
ecletica-1594	120	14	.	.	PUNCT
ecletica-1594	120	15	rmsd	rmsd	VERB
ecletica-1594	120	16	for	for	ADP
ecletica-1594	120	17	naj-1xsd	naj-1xsd	ADJ
ecletica-1594	120	18	and	and	CCONJ
ecletica-1594	120	19	penicillin-1xsd	penicillin-1xsd	NOUN
ecletica-1594	120	20	complexes	complex	NOUN
ecletica-1594	120	21	.	.	PUNCT
ecletica-1594	121	1	source	source	NOUN
ecletica-1594	121	2	:	:	PUNCT
ecletica-1594	121	3	elaborated	elaborate	VERB
ecletica-1594	121	4	by	by	ADP
ecletica-1594	121	5	the	the	DET
ecletica-1594	121	6	authors	author	NOUN
ecletica-1594	121	7	.	.	PUNCT
ecletica-1594	122	1	figure	figure	NOUN
ecletica-1594	122	2	5	5	NUM
ecletica-1594	122	3	.	.	PUNCT
ecletica-1594	122	4	rmsd	rmsd	VERB
ecletica-1594	122	5	for	for	ADP
ecletica-1594	122	6	nan-4wk3	nan-4wk3	NOUN
ecletica-1594	122	7	and	and	CCONJ
ecletica-1594	122	8	penicillin-4wk3	penicillin-4wk3	NOUN
ecletica-1594	122	9	complexes	complex	NOUN
ecletica-1594	122	10	.	.	PUNCT
ecletica-1594	123	1	source	source	NOUN
ecletica-1594	123	2	:	:	PUNCT
ecletica-1594	123	3	elaborated	elaborate	VERB
ecletica-1594	123	4	by	by	ADP
ecletica-1594	123	5	the	the	DET
ecletica-1594	123	6	authors	author	NOUN
ecletica-1594	123	7	.	.	PUNCT
ecletica-1594	124	1	3.3	3.3	NUM
ecletica-1594	124	2	.	.	PUNCT
ecletica-1594	125	1	adme	adme	ADJ
ecletica-1594	125	2	/	/	SYM
ecletica-1594	125	3	pharmacokinetic	pharmacokinetic	ADJ
ecletica-1594	125	4	predictions	prediction	NOUN
ecletica-1594	125	5	safety	safety	NOUN
ecletica-1594	125	6	is	be	AUX
ecletica-1594	125	7	paramount	paramount	ADJ
ecletica-1594	125	8	in	in	ADP
ecletica-1594	125	9	drug	drug	NOUN
ecletica-1594	125	10	usage	usage	NOUN
ecletica-1594	125	11	;	;	PUNCT
ecletica-1594	125	12	in	in	ADP
ecletica-1594	125	13	this	this	DET
ecletica-1594	125	14	research	research	NOUN
ecletica-1594	125	15	,	,	PUNCT
ecletica-1594	125	16	the	the	DET
ecletica-1594	125	17	physicochemical	physicochemical	ADJ
ecletica-1594	125	18	and	and	CCONJ
ecletica-1594	125	19	admet	admet	NOUN
ecletica-1594	125	20	properties	property	NOUN
ecletica-1594	125	21	of	of	ADP
ecletica-1594	125	22	the	the	DET
ecletica-1594	125	23	ligands	ligand	NOUN
ecletica-1594	125	24	were	be	AUX
ecletica-1594	125	25	assessed	assess	VERB
ecletica-1594	125	26	.	.	PUNCT
ecletica-1594	126	1	however	however	ADV
ecletica-1594	126	2	,	,	PUNCT
ecletica-1594	126	3	there	there	PRON
ecletica-1594	126	4	are	be	VERB
ecletica-1594	126	5	lots	lot	NOUN
ecletica-1594	126	6	of	of	ADP
ecletica-1594	126	7	drug	drug	NOUN
ecletica-1594	126	8	candidates	candidate	NOUN
ecletica-1594	126	9	that	that	PRON
ecletica-1594	126	10	are	be	AUX
ecletica-1594	126	11	not	not	PART
ecletica-1594	126	12	drug	drug	NOUN
ecletica-1594	126	13	-	-	PUNCT
ecletica-1594	126	14	like	like	ADJ
ecletica-1594	126	15	.	.	PUNCT
ecletica-1594	127	1	lipinski	lipinski	PROPN
ecletica-1594	127	2	’s	’s	PART
ecletica-1594	127	3	rule	rule	NOUN
ecletica-1594	127	4	of	of	ADP
ecletica-1594	127	5	five	five	NUM
ecletica-1594	127	6	(	(	PUNCT
ecletica-1594	127	7	ro5	ro5	NOUN
ecletica-1594	127	8	)	)	PUNCT
ecletica-1594	127	9	was	be	AUX
ecletica-1594	127	10	used	use	VERB
ecletica-1594	127	11	to	to	PART
ecletica-1594	127	12	access	access	VERB
ecletica-1594	127	13	the	the	DET
ecletica-1594	127	14	physicochemical	physicochemical	ADJ
ecletica-1594	127	15	properties	property	NOUN
ecletica-1594	127	16	of	of	ADP
ecletica-1594	127	17	the	the	DET
ecletica-1594	127	18	ligands	ligand	NOUN
ecletica-1594	127	19	,	,	PUNCT
ecletica-1594	127	20	which	which	PRON
ecletica-1594	127	21	include	include	VERB
ecletica-1594	127	22	molecular	molecular	ADJ
ecletica-1594	127	23	weight	weight	NOUN
ecletica-1594	127	24	(	(	PUNCT
ecletica-1594	127	25	150	150	NUM
ecletica-1594	127	26	≤	≤	NUM
ecletica-1594	127	27	mw	mw	VERB
ecletica-1594	127	28	≤	≤	NUM
ecletica-1594	127	29	500	500	NUM
ecletica-1594	127	30	)	)	PUNCT
ecletica-1594	127	31	,	,	PUNCT
ecletica-1594	127	32	lipophilicity	lipophilicity	NOUN
ecletica-1594	127	33	(	(	PUNCT
ecletica-1594	127	34	log	log	VERB
ecletica-1594	127	35	p	p	NOUN
ecletica-1594	127	36	≤	≤	NUM
ecletica-1594	127	37	5	5	NUM
ecletica-1594	127	38	)	)	PUNCT
ecletica-1594	127	39	,	,	PUNCT
ecletica-1594	127	40	number	number	NOUN
ecletica-1594	127	41	of	of	ADP
ecletica-1594	127	42	rotatable	rotatable	ADJ
ecletica-1594	127	43	bonds	bond	NOUN
ecletica-1594	127	44	(	(	PUNCT
ecletica-1594	127	45	rotbs	rotbs	ADJ
ecletica-1594	127	46	≤	≤	NUM
ecletica-1594	127	47	10	10	NUM
ecletica-1594	127	48	)	)	PUNCT
ecletica-1594	127	49	,	,	PUNCT
ecletica-1594	127	50	hydrogen	hydrogen	NOUN
ecletica-1594	127	51	bond	bond	NOUN
ecletica-1594	127	52	donor	donor	NOUN
ecletica-1594	127	53	(	(	PUNCT
ecletica-1594	127	54	hbd	hbd	NOUN
ecletica-1594	127	55	≤	≤	NUM
ecletica-1594	127	56	5	5	NUM
ecletica-1594	127	57	)	)	PUNCT
ecletica-1594	127	58	and	and	CCONJ
ecletica-1594	127	59	hydrogen	hydrogen	NOUN
ecletica-1594	127	60	bond	bond	NOUN
ecletica-1594	127	61	acceptor	acceptor	NOUN
ecletica-1594	127	62	(	(	PUNCT
ecletica-1594	127	63	hba	hba	PROPN
ecletica-1594	127	64	≤	≤	NUM
ecletica-1594	127	65	10	10	NUM
ecletica-1594	127	66	)	)	PUNCT
ecletica-1594	127	67	(	(	PUNCT
ecletica-1594	127	68	daina	daina	PROPN
ecletica-1594	127	69	et	et	PROPN
ecletica-1594	127	70	al	al	PROPN
ecletica-1594	127	71	.	.	PROPN
ecletica-1594	127	72	,	,	PUNCT
ecletica-1594	127	73	2017	2017	NUM
ecletica-1594	127	74	;	;	PUNCT
ecletica-1594	127	75	lipinski	lipinski	PROPN
ecletica-1594	127	76	et	et	PROPN
ecletica-1594	127	77	al	al	PROPN
ecletica-1594	127	78	.	.	PROPN
ecletica-1594	127	79	,	,	PUNCT
ecletica-1594	127	80	2004	2004	NUM
ecletica-1594	127	81	)	)	PUNCT
ecletica-1594	127	82	.	.	PUNCT
ecletica-1594	128	1	all	all	DET
ecletica-1594	128	2	the	the	DET
ecletica-1594	128	3	compounds	compound	NOUN
ecletica-1594	128	4	and	and	CCONJ
ecletica-1594	128	5	the	the	DET
ecletica-1594	128	6	standard	standard	ADJ
ecletica-1594	128	7	drugs	drug	NOUN
ecletica-1594	128	8	obeyed	obey	VERB
ecletica-1594	128	9	lipinski‘s	lipinski‘s	ADP
ecletica-1594	128	10	rule	rule	NOUN
ecletica-1594	128	11	for	for	ADP
ecletica-1594	128	12	hydrogen	hydrogen	NOUN
ecletica-1594	128	13	bond	bond	NOUN
ecletica-1594	128	14	donors	donor	NOUN
ecletica-1594	128	15	,	,	PUNCT
ecletica-1594	128	16	hydrogen	hydrogen	NOUN
ecletica-1594	128	17	bond	bond	NOUN
ecletica-1594	128	18	acceptors	acceptor	NOUN
ecletica-1594	128	19	and	and	CCONJ
ecletica-1594	128	20	molecular	molecular	ADJ
ecletica-1594	128	21	weight	weight	NOUN
ecletica-1594	128	22	and	and	CCONJ
ecletica-1594	128	23	wlogp	wlogp	NOUN
ecletica-1594	128	24	.	.	PUNCT
ecletica-1594	129	1	they	they	PRON
ecletica-1594	129	2	are	be	AUX
ecletica-1594	129	3	moderately	moderately	ADV
ecletica-1594	129	4	soluble	soluble	ADJ
ecletica-1594	129	5	in	in	ADP
ecletica-1594	129	6	water	water	NOUN
ecletica-1594	129	7	,	,	PUNCT
ecletica-1594	129	8	whereas	whereas	SCONJ
ecletica-1594	129	9	standard	standard	ADJ
ecletica-1594	129	10	medicines	medicine	NOUN
ecletica-1594	129	11	are	be	AUX
ecletica-1594	129	12	highly	highly	ADV
ecletica-1594	129	13	soluble	soluble	ADJ
ecletica-1594	129	14	.	.	PUNCT
ecletica-1594	130	1	however	however	ADV
ecletica-1594	130	2	,	,	PUNCT
ecletica-1594	130	3	all	all	DET
ecletica-1594	130	4	the	the	DET
ecletica-1594	130	5	ligands	ligand	NOUN
ecletica-1594	130	6	have	have	VERB
ecletica-1594	130	7	tpsa	tpsa	NOUN
ecletica-1594	130	8	values	value	NOUN
ecletica-1594	130	9	between	between	ADP
ecletica-1594	130	10	132.75	132.75	NUM
ecletica-1594	130	11	and	and	CCONJ
ecletica-1594	130	12	165.01	165.01	NUM
ecletica-1594	130	13	å	å	NOUN
ecletica-1594	130	14	,	,	PUNCT
ecletica-1594	130	15	which	which	PRON
ecletica-1594	130	16	are	be	AUX
ecletica-1594	130	17	higher	high	ADJ
ecletica-1594	130	18	than	than	ADP
ecletica-1594	130	19	131.6	131.6	NUM
ecletica-1594	130	20	å	å	NOUN
ecletica-1594	130	21	as	as	ADP
ecletica-1594	130	22	the	the	DET
ecletica-1594	130	23	upper	upper	ADJ
ecletica-1594	130	24	limit	limit	NOUN
ecletica-1594	130	25	(	(	PUNCT
ecletica-1594	130	26	table	table	NOUN
ecletica-1594	130	27	4	4	NUM
ecletica-1594	130	28	)	)	PUNCT
ecletica-1594	130	29	.	.	PUNCT
ecletica-1594	131	1	lack	lack	NOUN
ecletica-1594	131	2	of	of	ADP
ecletica-1594	131	3	efficacy	efficacy	NOUN
ecletica-1594	131	4	and	and	CCONJ
ecletica-1594	131	5	safety	safety	NOUN
ecletica-1594	131	6	are	be	AUX
ecletica-1594	131	7	the	the	DET
ecletica-1594	131	8	two	two	NUM
ecletica-1594	131	9	major	major	ADJ
ecletica-1594	131	10	causes	cause	NOUN
ecletica-1594	131	11	leading	lead	VERB
ecletica-1594	131	12	to	to	ADP
ecletica-1594	131	13	drug	drug	NOUN
ecletica-1594	131	14	failure	failure	NOUN
ecletica-1594	131	15	(	(	PUNCT
ecletica-1594	131	16	sun	sun	NOUN
ecletica-1594	131	17	et	et	PROPN
ecletica-1594	131	18	al	al	PROPN
ecletica-1594	131	19	.	.	PROPN
ecletica-1594	131	20	,	,	PUNCT
ecletica-1594	131	21	2022	2022	NUM
ecletica-1594	131	22	)	)	PUNCT
ecletica-1594	131	23	,	,	PUNCT
ecletica-1594	131	24	which	which	PRON
ecletica-1594	131	25	means	mean	VERB
ecletica-1594	131	26	the	the	DET
ecletica-1594	131	27	absorption	absorption	NOUN
ecletica-1594	131	28	,	,	PUNCT
ecletica-1594	131	29	distribution	distribution	NOUN
ecletica-1594	131	30	,	,	PUNCT
ecletica-1594	131	31	metabolism	metabolism	NOUN
ecletica-1594	131	32	,	,	PUNCT
ecletica-1594	131	33	excretion	excretion	NOUN
ecletica-1594	131	34	,	,	PUNCT
ecletica-1594	131	35	and	and	CCONJ
ecletica-1594	131	36	toxicity	toxicity	NOUN
ecletica-1594	131	37	(	(	PUNCT
ecletica-1594	131	38	admet	admet	ADJ
ecletica-1594	131	39	)	)	PUNCT
ecletica-1594	131	40	properties	property	NOUN
ecletica-1594	131	41	of	of	ADP
ecletica-1594	131	42	chemicals	chemical	NOUN
ecletica-1594	131	43	play	play	VERB
ecletica-1594	131	44	vital	vital	ADJ
ecletica-1594	131	45	roles	role	NOUN
ecletica-1594	131	46	in	in	ADP
ecletica-1594	131	47	every	every	DET
ecletica-1594	131	48	stage	stage	NOUN
ecletica-1594	131	49	of	of	ADP
ecletica-1594	131	50	drug	drug	NOUN
ecletica-1594	131	51	discovery	discovery	NOUN
ecletica-1594	131	52	and	and	CCONJ
ecletica-1594	131	53	development	development	NOUN
ecletica-1594	131	54	.	.	PUNCT
ecletica-1594	132	1	hence	hence	ADV
ecletica-1594	132	2	,	,	PUNCT
ecletica-1594	132	3	using	use	VERB
ecletica-1594	132	4	admet	admet	PROPN
ecletica-1594	132	5	profiling	profiling	NOUN
ecletica-1594	132	6	is	be	AUX
ecletica-1594	132	7	considered	consider	VERB
ecletica-1594	132	8	one	one	NUM
ecletica-1594	132	9	way	way	NOUN
ecletica-1594	132	10	to	to	PART
ecletica-1594	132	11	reduce	reduce	VERB
ecletica-1594	132	12	likely	likely	ADJ
ecletica-1594	132	13	challenges	challenge	NOUN
ecletica-1594	132	14	associated	associate	VERB
ecletica-1594	132	15	with	with	ADP
ecletica-1594	132	16	clinical	clinical	ADJ
ecletica-1594	132	17	trial	trial	NOUN
ecletica-1594	132	18	treatments	treatment	NOUN
ecletica-1594	132	19	(	(	PUNCT
ecletica-1594	132	20	daina	daina	PROPN
ecletica-1594	132	21	and	and	CCONJ
ecletica-1594	132	22	zoete	zoete	NOUN
ecletica-1594	132	23	,	,	PUNCT
ecletica-1594	132	24	2016	2016	NUM
ecletica-1594	132	25	;	;	PUNCT
ecletica-1594	132	26	darvas	darvas	PROPN
ecletica-1594	132	27	et	et	PROPN
ecletica-1594	132	28	al	al	PROPN
ecletica-1594	132	29	.	.	PROPN
ecletica-1594	132	30	,	,	PUNCT
ecletica-1594	132	31	2002	2002	NUM
ecletica-1594	132	32	)	)	PUNCT
ecletica-1594	132	33	.	.	PUNCT
ecletica-1594	133	1	compounds	compound	VERB
ecletica-1594	133	2	nah	nah	INTJ
ecletica-1594	133	3	,	,	PUNCT
ecletica-1594	133	4	nai	nai	PROPN
ecletica-1594	133	5	,	,	PUNCT
ecletica-1594	133	6	naj	naj	PROPN
ecletica-1594	133	7	,	,	PUNCT
ecletica-1594	133	8	nak	nak	NOUN
ecletica-1594	133	9	,	,	PUNCT
ecletica-1594	133	10	nal	nal	PROPN
ecletica-1594	133	11	,	,	PUNCT
ecletica-1594	133	12	nam	nam	PROPN
ecletica-1594	133	13	,	,	PUNCT
ecletica-1594	133	14	nan	nan	PROPN
ecletica-1594	133	15	and	and	CCONJ
ecletica-1594	133	16	5ad	5ad	PROPN
ecletica-1594	133	17	were	be	AUX
ecletica-1594	133	18	inhibitors	inhibitor	NOUN
ecletica-1594	133	19	to	to	PART
ecletica-1594	133	20	cyp3a4	cyp3a4	VERB
ecletica-1594	133	21	;	;	PUNCT
ecletica-1594	133	22	therefore	therefore	ADV
ecletica-1594	133	23	,	,	PUNCT
ecletica-1594	133	24	they	they	PRON
ecletica-1594	133	25	may	may	AUX
ecletica-1594	133	26	cause	cause	VERB
ecletica-1594	133	27	an	an	DET
ecletica-1594	133	28	elevation	elevation	NOUN
ecletica-1594	133	29	in	in	ADP
ecletica-1594	133	30	the	the	DET
ecletica-1594	133	31	concentration	concentration	NOUN
ecletica-1594	133	32	of	of	ADP
ecletica-1594	133	33	the	the	DET
ecletica-1594	133	34	corresponding	corresponding	ADJ
ecletica-1594	133	35	compounds	compound	NOUN
ecletica-1594	133	36	,	,	PUNCT
ecletica-1594	133	37	leading	lead	VERB
ecletica-1594	133	38	to	to	ADP
ecletica-1594	133	39	drug	drug	NOUN
ecletica-1594	133	40	overdose	overdose	NOUN
ecletica-1594	133	41	(	(	PUNCT
ecletica-1594	133	42	conrad	conrad	PROPN
ecletica-1594	133	43	et	et	PROPN
ecletica-1594	133	44	al	al	PROPN
ecletica-1594	133	45	.	.	PROPN
ecletica-1594	133	46	,	,	PUNCT
ecletica-1594	133	47	2024	2024	NUM
ecletica-1594	133	48	)	)	PUNCT
ecletica-1594	133	49	.	.	PUNCT
ecletica-1594	134	1	additionally	additionally	ADV
ecletica-1594	134	2	,	,	PUNCT
ecletica-1594	134	3	all	all	DET
ecletica-1594	134	4	the	the	DET
ecletica-1594	134	5	compounds	compound	NOUN
ecletica-1594	134	6	except	except	SCONJ
ecletica-1594	134	7	compound	compound	NOUN
ecletica-1594	134	8	nan	nan	PROPN
ecletica-1594	134	9	exhibit	exhibit	VERB
ecletica-1594	134	10	high	high	ADJ
ecletica-1594	134	11	gi	gi	NOUN
ecletica-1594	134	12	absorption	absorption	NOUN
ecletica-1594	134	13	,	,	PUNCT
ecletica-1594	134	14	and	and	CCONJ
ecletica-1594	134	15	none	none	NOUN
ecletica-1594	134	16	of	of	ADP
ecletica-1594	134	17	the	the	DET
ecletica-1594	134	18	compounds	compound	NOUN
ecletica-1594	134	19	possess	possess	VERB
ecletica-1594	134	20	blood	blood	NOUN
ecletica-1594	134	21	–	–	PUNCT
ecletica-1594	134	22	brain	brain	NOUN
ecletica-1594	134	23	barrier	barrier	NOUN
ecletica-1594	134	24	bbb	bbb	PROPN
ecletica-1594	134	25	penetration	penetration	NOUN
ecletica-1594	134	26	.	.	PUNCT
ecletica-1594	135	1	nac	nac	PROPN
ecletica-1594	135	2	,	,	PUNCT
ecletica-1594	135	3	nad	nad	PROPN
ecletica-1594	135	4	,	,	PUNCT
ecletica-1594	135	5	nae	nae	PROPN
ecletica-1594	135	6	,	,	PUNCT
ecletica-1594	135	7	nag	nag	VERB
ecletica-1594	135	8	,	,	PUNCT
ecletica-1594	135	9	nan	nan	PROPN
ecletica-1594	135	10	,	,	PUNCT
ecletica-1594	135	11	naf	naf	PROPN
ecletica-1594	135	12	,	,	PUNCT
ecletica-1594	135	13	nak	nak	PROPN
ecletica-1594	135	14	,	,	PUNCT
ecletica-1594	135	15	nai	nai	PROPN
ecletica-1594	135	16	,	,	PUNCT
ecletica-1594	135	17	and	and	CCONJ
ecletica-1594	135	18	nam	nam	NOUN
ecletica-1594	135	19	were	be	AUX
ecletica-1594	135	20	identified	identify	VERB
ecletica-1594	135	21	as	as	ADP
ecletica-1594	135	22	pgp	pgp	NOUN
ecletica-1594	135	23	substrates	substrate	NOUN
ecletica-1594	135	24	(	(	PUNCT
ecletica-1594	135	25	i.e.	i.e.	X
ecletica-1594	135	26	they	they	PRON
ecletica-1594	135	27	can	can	AUX
ecletica-1594	135	28	be	be	AUX
ecletica-1594	135	29	transported	transport	VERB
ecletica-1594	135	30	out	out	ADP
ecletica-1594	135	31	of	of	ADP
ecletica-1594	135	32	the	the	DET
ecletica-1594	135	33	cell	cell	NOUN
ecletica-1594	135	34	.	.	PUNCT
ecletica-1594	136	1	additionally	additionally	ADV
ecletica-1594	136	2	,	,	PUNCT
ecletica-1594	136	3	compounds	compound	VERB
ecletica-1594	136	4	nad	nad	PROPN
ecletica-1594	136	5	,	,	PUNCT
ecletica-1594	136	6	nae	nae	PROPN
ecletica-1594	136	7	,	,	PUNCT
ecletica-1594	136	8	and	and	CCONJ
ecletica-1594	136	9	naf	naf	PROPN
ecletica-1594	136	10	could	could	AUX
ecletica-1594	136	11	be	be	AUX
ecletica-1594	136	12	inhibitors	inhibitor	NOUN
ecletica-1594	136	13	of	of	ADP
ecletica-1594	136	14	cyp2c19	cyp2c19	NOUN
ecletica-1594	136	15	,	,	PUNCT
ecletica-1594	136	16	while	while	SCONJ
ecletica-1594	136	17	compounds	compound	NOUN
ecletica-1594	136	18	nac	nac	PROPN
ecletica-1594	136	19	,	,	PUNCT
ecletica-1594	136	20	nag	nag	VERB
ecletica-1594	136	21	,	,	PUNCT
ecletica-1594	136	22	nan	nan	PROPN
ecletica-1594	136	23	,	,	PUNCT
ecletica-1594	136	24	nak	nak	PROPN
ecletica-1594	136	25	,	,	PUNCT
ecletica-1594	136	26	5ac	5ac	NOUN
ecletica-1594	136	27	and	and	CCONJ
ecletica-1594	136	28	nam	nam	NOUN
ecletica-1594	136	29	could	could	AUX
ecletica-1594	136	30	be	be	AUX
ecletica-1594	136	31	substrates	substrate	NOUN
ecletica-1594	136	32	for	for	ADP
ecletica-1594	136	33	cyp2c19	cyp2c19	NOUN
ecletica-1594	136	34	.	.	PUNCT
ecletica-1594	137	1	none	none	NOUN
ecletica-1594	137	2	of	of	ADP
ecletica-1594	137	3	the	the	DET
ecletica-1594	137	4	compounds	compound	NOUN
ecletica-1594	137	5	could	could	AUX
ecletica-1594	137	6	be	be	AUX
ecletica-1594	137	7	inhibitor	inhibitor	NOUN
ecletica-1594	137	8	of	of	ADP
ecletica-1594	137	9	cyp2c9	cyp2c9	NOUN
ecletica-1594	137	10	,	,	PUNCT
ecletica-1594	137	11	and	and	CCONJ
ecletica-1594	137	12	nac	nac	PROPN
ecletica-1594	137	13	was	be	AUX
ecletica-1594	137	14	an	an	DET
ecletica-1594	137	15	inhibitor	inhibitor	NOUN
ecletica-1594	137	16	of	of	ADP
ecletica-1594	137	17	cyp2d6	cyp2d6	NOUN
ecletica-1594	137	18	(	(	PUNCT
ecletica-1594	137	19	table	table	NOUN
ecletica-1594	137	20	5	5	NUM
ecletica-1594	137	21	)	)	PUNCT
ecletica-1594	137	22	.	.	PUNCT
ecletica-1594	138	1	the	the	DET
ecletica-1594	138	2	admet	admet	PROPN
ecletica-1594	138	3	results	result	NOUN
ecletica-1594	138	4	revealed	reveal	VERB
ecletica-1594	138	5	that	that	SCONJ
ecletica-1594	138	6	naf	naf	PROPN
ecletica-1594	138	7	,	,	PUNCT
ecletica-1594	138	8	nai	nai	PROPN
ecletica-1594	138	9	,	,	PUNCT
ecletica-1594	138	10	nak	nak	PROPN
ecletica-1594	138	11	nan	nan	PROPN
ecletica-1594	138	12	and	and	CCONJ
ecletica-1594	138	13	5ac	5ac	NOUN
ecletica-1594	138	14	have	have	VERB
ecletica-1594	138	15	attractive	attractive	ADJ
ecletica-1594	138	16	pharmacokinetic	pharmacokinetic	ADJ
ecletica-1594	138	17	properties	property	NOUN
ecletica-1594	138	18	(	(	PUNCT
ecletica-1594	138	19	table	table	NOUN
ecletica-1594	138	20	5	5	NUM
ecletica-1594	138	21	)	)	PUNCT
ecletica-1594	138	22	.	.	PUNCT
ecletica-1594	139	1	table	table	NOUN
ecletica-1594	139	2	4	4	NUM
ecletica-1594	139	3	.	.	PUNCT
ecletica-1594	139	4	physicochemical	physicochemical	ADJ
ecletica-1594	139	5	properties	property	NOUN
ecletica-1594	139	6	of	of	ADP
ecletica-1594	139	7	sulfamidophosphonates	sulfamidophosphonate	NOUN
ecletica-1594	139	8	.	.	PUNCT
ecletica-1594	140	1	drugs	drug	NOUN
ecletica-1594	140	2	mw	mw	VERB
ecletica-1594	140	3	g	g	NOUN
ecletica-1594	140	4	/	/	SYM
ecletica-1594	140	5	mol	mol	ADP
ecletica-1594	140	6	heavy	heavy	ADJ
ecletica-1594	140	7	atoms	atom	NOUN
ecletica-1594	140	8	aromatic	aromatic	ADJ
ecletica-1594	140	9	heavy	heavy	ADJ
ecletica-1594	140	10	atoms	atom	NOUN
ecletica-1594	140	11	fraction	fraction	NOUN
ecletica-1594	140	12	csp3	csp3	PROPN
ecletica-1594	140	13	rotatable	rotatable	ADJ
ecletica-1594	140	14	bonds	bond	NOUN
ecletica-1594	140	15	hba	hba	PROPN
ecletica-1594	140	16	hbd	hbd	PROPN
ecletica-1594	140	17	molar	molar	PROPN
ecletica-1594	140	18	ref	ref	PROPN
ecletica-1594	140	19	tpsa	tpsa	PROPN
ecletica-1594	140	20	lipinski	lipinski	PROPN
ecletica-1594	140	21	violation	violation	PROPN
ecletica-1594	140	22	log	log	VERB
ecletica-1594	140	23	p	p	PROPN
ecletica-1594	140	24	(	(	PUNCT
ecletica-1594	140	25	o	o	NOUN
ecletica-1594	140	26	/	/	SYM
ecletica-1594	140	27	w	w	NOUN
ecletica-1594	140	28	)	)	PUNCT
ecletica-1594	140	29	bio	bio	NOUN
ecletica-1594	140	30	score	score	PROPN
ecletica-1594	140	31	h2o	h2o	PROPN
ecletica-1594	140	32	solubility	solubility	NOUN
ecletica-1594	140	33	nah	nah	CCONJ
ecletica-1594	140	34	478.50	478.50	NUM
ecletica-1594	140	35	32	32	NUM
ecletica-1594	140	36	16	16	NUM
ecletica-1594	140	37	0.32	0.32	NUM
ecletica-1594	140	38	10	10	NUM
ecletica-1594	140	39	7	7	NUM
ecletica-1594	140	40	2	2	NUM
ecletica-1594	140	41	124.79	124.79	NUM
ecletica-1594	140	42	132.75	132.75	NUM
ecletica-1594	140	43	0	0	NUM
ecletica-1594	140	44	3.03	3.03	NUM
ecletica-1594	140	45	0.55	0.55	NUM
ecletica-1594	140	46	mod	mod	ADJ
ecletica-1594	140	47	soluble	soluble	ADJ
ecletica-1594	140	48	nai	nai	X
ecletica-1594	141	1	478.50	478.50	NUM
ecletica-1594	141	2	32	32	NUM
ecletica-1594	141	3	16	16	NUM
ecletica-1594	141	4	0.32	0.32	NUM
ecletica-1594	141	5	9	9	NUM
ecletica-1594	141	6	7	7	NUM
ecletica-1594	141	7	2	2	NUM
ecletica-1594	141	8	124.94	124.94	NUM
ecletica-1594	141	9	132.75	132.75	NUM
ecletica-1594	141	10	0	0	NUM
ecletica-1594	141	11	3.29	3.29	NUM
ecletica-1594	141	12	0.55	0.55	NUM
ecletica-1594	141	13	mod	mod	ADJ
ecletica-1594	141	14	soluble	soluble	ADJ
ecletica-1594	141	15	naj	naj	NOUN
ecletica-1594	141	16	464.47	464.47	NUM
ecletica-1594	141	17	31	31	NUM
ecletica-1594	141	18	16	16	NUM
ecletica-1594	141	19	0.29	0.29	NUM
ecletica-1594	141	20	9	9	NUM
ecletica-1594	141	21	7	7	NUM
ecletica-1594	141	22	2	2	NUM
ecletica-1594	141	23	119.98	119.98	NUM
ecletica-1594	141	24	132.75	132.75	NUM
ecletica-1594	141	25	0	0	NUM
ecletica-1594	141	26	2.94	2.94	NUM
ecletica-1594	141	27	0.55	0.55	NUM
ecletica-1594	141	28	mod	mod	ADJ
ecletica-1594	141	29	soluble	soluble	ADJ
ecletica-1594	141	30	nak	nak	PROPN
ecletica-1594	141	31	478.5	478.5	NUM
ecletica-1594	141	32	32	32	NUM
ecletica-1594	141	33	16	16	NUM
ecletica-1594	141	34	0.32	0.32	NUM
ecletica-1594	141	35	9	9	NUM
ecletica-1594	141	36	7	7	NUM
ecletica-1594	141	37	2	2	NUM
ecletica-1594	141	38	124.94	124.94	NUM
ecletica-1594	141	39	132.75	132.75	NUM
ecletica-1594	141	40	0	0	NUM
ecletica-1594	141	41	3.33	3.33	NUM
ecletica-1594	141	42	0.55	0.55	NUM
ecletica-1594	141	43	mod	mod	ADJ
ecletica-1594	141	44	soluble	soluble	ADJ
ecletica-1594	141	45	nal	nal	NOUN
ecletica-1594	141	46	478.48	478.48	NUM
ecletica-1594	141	47	32	32	NUM
ecletica-1594	141	48	16	16	NUM
ecletica-1594	141	49	0.24	0.24	NUM
ecletica-1594	141	50	9	9	NUM
ecletica-1594	141	51	6	6	NUM
ecletica-1594	141	52	3	3	NUM
ecletica-1594	141	53	126.71	126.71	NUM
ecletica-1594	141	54	146.72	146.72	NUM
ecletica-1594	141	55	0	0	NUM
ecletica-1594	141	56	2.84	2.84	NUM
ecletica-1594	141	57	0.55	0.55	NUM
ecletica-1594	141	58	mod	mod	ADJ
ecletica-1594	141	59	soluble	soluble	ADJ
ecletica-1594	141	60	nam	nam	NOUN
ecletica-1594	141	61	497.48	497.48	NUM
ecletica-1594	141	62	33	33	NUM
ecletica-1594	141	63	16	16	NUM
ecletica-1594	141	64	0.29	0.29	NUM
ecletica-1594	141	65	10	10	NUM
ecletica-1594	141	66	8	8	NUM
ecletica-1594	141	67	3	3	NUM
ecletica-1594	141	68	125.11	125.11	NUM
ecletica-1594	141	69	144.78	144.78	NUM
ecletica-1594	141	70	0	0	NUM
ecletica-1594	141	71	3.23	3.23	NUM
ecletica-1594	141	72	0.55	0.55	NUM
ecletica-1594	141	73	mod	mod	ADJ
ecletica-1594	141	74	soluble	soluble	ADJ
ecletica-1594	141	75	nan	nan	PROPN
ecletica-1594	141	76	495.49	495.49	NUM
ecletica-1594	141	77	33	33	NUM
ecletica-1594	141	78	16	16	NUM
ecletica-1594	141	79	0.29	0.29	NUM
ecletica-1594	141	80	10	10	NUM
ecletica-1594	141	81	8	8	NUM
ecletica-1594	141	82	4	4	NUM
ecletica-1594	141	83	127.18	127.18	NUM
ecletica-1594	141	84	165.01	165.01	NUM
ecletica-1594	141	85	0	0	NUM
ecletica-1594	141	86	0.55	0.55	NUM
ecletica-1594	141	87	mod	mod	ADJ
ecletica-1594	141	88	soluble	soluble	ADJ
ecletica-1594	141	89	5ad	5ad	NOUN
ecletica-1594	141	90	429.43	429.43	NUM
ecletica-1594	141	91	28	28	NUM
ecletica-1594	141	92	10	10	NUM
ecletica-1594	141	93	0.47	0.47	NUM
ecletica-1594	141	94	7	7	NUM
ecletica-1594	141	95	8	8	NUM
ecletica-1594	141	96	2	2	NUM
ecletica-1594	141	97	114.55	114.55	NUM
ecletica-1594	141	98	135.96	135.96	NUM
ecletica-1594	141	99	0	0	NUM
ecletica-1594	141	100	1.49	1.49	NUM
ecletica-1594	141	101	0.55	0.55	NUM
ecletica-1594	141	102	soluble	soluble	ADJ
ecletica-1594	141	103	penicillin	penicillin	NOUN
ecletica-1594	141	104	334.39	334.39	NUM
ecletica-1594	141	105	23	23	NUM
ecletica-1594	141	106	6	6	NUM
ecletica-1594	141	107	0.44	0.44	NUM
ecletica-1594	141	108	5	5	NUM
ecletica-1594	141	109	4	4	NUM
ecletica-1594	141	110	2	2	NUM
ecletica-1594	141	111	90.54	90.54	NUM
ecletica-1594	141	112	121.13	121.13	NUM
ecletica-1594	141	113	0	0	NUM
ecletica-1594	141	114	1.39	1.39	NUM
ecletica-1594	141	115	0.55	0.55	NUM
ecletica-1594	141	116	soluble	soluble	ADJ
ecletica-1594	141	117	sulfamethoxazole	sulfamethoxazole	NOUN
ecletica-1594	141	118	253.28	253.28	NUM
ecletica-1594	141	119	17	17	NUM
ecletica-1594	141	120	11	11	NUM
ecletica-1594	141	121	0.1	0.1	NUM
ecletica-1594	141	122	3	3	NUM
ecletica-1594	141	123	4	4	NUM
ecletica-1594	141	124	2	2	NUM
ecletica-1594	141	125	62.99	62.99	NUM
ecletica-1594	141	126	106.6	106.6	NUM
ecletica-1594	141	127	0	0	NUM
ecletica-1594	141	128	-0.15	-0.15	NUM
ecletica-1594	141	129	0.55	0.55	NUM
ecletica-1594	141	130	soluble	soluble	ADJ
ecletica-1594	141	131	source	source	NOUN
ecletica-1594	141	132	:	:	PUNCT
ecletica-1594	141	133	elaborated	elaborate	VERB
ecletica-1594	141	134	by	by	ADP
ecletica-1594	141	135	the	the	DET
ecletica-1594	141	136	authors	author	NOUN
ecletica-1594	141	137	.	.	PUNCT
ecletica-1594	142	1	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	X
ecletica-1594	142	2	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	X
ecletica-1594	142	3	original	original	ADJ
ecletica-1594	142	4	article	article	NOUN
ecletica-1594	142	5	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	X
ecletica-1594	142	6	issn	issn	VERB
ecletica-1594	142	7	1678	1678	NUM
ecletica-1594	142	8	-	-	SYM
ecletica-1594	142	9	4618	4618	NUM
ecletica-1594	142	10	page	page	NOUN
ecletica-1594	142	11	13/14	13/14	NUM
ecletica-1594	142	12	table	table	NOUN
ecletica-1594	142	13	5	5	NUM
ecletica-1594	142	14	.	.	PUNCT
ecletica-1594	142	15	pharmacokinetics	pharmacokinetic	NOUN
ecletica-1594	142	16	properties	property	NOUN
ecletica-1594	142	17	of	of	ADP
ecletica-1594	142	18	sulfamidophosphonates	sulfamidophosphonate	NOUN
ecletica-1594	142	19	.	.	PUNCT
ecletica-1594	143	1	drugs	drug	NOUN
ecletica-1594	143	2	gi	gi	VERB
ecletica-1594	143	3	absorption	absorption	NOUN
ecletica-1594	143	4	bbb	bbb	PROPN
ecletica-1594	143	5	permeant	permeant	PROPN
ecletica-1594	143	6	p	p	NOUN
ecletica-1594	143	7	-	-	PUNCT
ecletica-1594	143	8	gp	gp	NOUN
ecletica-1594	143	9	substrate	substrate	NOUN
ecletica-1594	143	10	cyp1a2	cyp1a2	ADJ
ecletica-1594	143	11	inhibitor	inhibitor	NOUN
ecletica-1594	143	12	cyp2c19	cyp2c19	NOUN
ecletica-1594	143	13	inhibitor	inhibitor	NOUN
ecletica-1594	143	14	cyp2c9	cyp2c9	NOUN
ecletica-1594	143	15	inhibitor	inhibitor	NOUN
ecletica-1594	143	16	cyp2d6	cyp2d6	NOUN
ecletica-1594	143	17	inhibitor	inhibitor	NOUN
ecletica-1594	143	18	cyp3a4	cyp3a4	PROPN
ecletica-1594	143	19	inhibitor	inhibitor	PROPN
ecletica-1594	143	20	log	log	NOUN
ecletica-1594	143	21	kp	kp	PROPN
ecletica-1594	143	22	(	(	PUNCT
ecletica-1594	143	23	skin	skin	NOUN
ecletica-1594	143	24	permeation	permeation	NOUN
ecletica-1594	143	25	)	)	PUNCT
ecletica-1594	143	26	cm	cm	PROPN
ecletica-1594	143	27	/	/	SYM
ecletica-1594	143	28	s	s	VERB
ecletica-1594	144	1	nah	nah	INTJ
ecletica-1594	144	2	low	low	ADJ
ecletica-1594	145	1	no	no	INTJ
ecletica-1594	145	2	yes	yes	INTJ
ecletica-1594	146	1	no	no	INTJ
ecletica-1594	147	1	yes	yes	INTJ
ecletica-1594	148	1	yes	yes	INTJ
ecletica-1594	149	1	no	no	INTJ
ecletica-1594	149	2	yes	yes	INTJ
ecletica-1594	149	3	–	–	PUNCT
ecletica-1594	149	4	7.28	7.28	NUM
ecletica-1594	149	5	nai	nai	NOUN
ecletica-1594	149	6	low	low	ADJ
ecletica-1594	150	1	no	no	INTJ
ecletica-1594	150	2	no	no	INTJ
ecletica-1594	151	1	no	no	INTJ
ecletica-1594	152	1	yes	yes	INTJ
ecletica-1594	153	1	yes	yes	INTJ
ecletica-1594	154	1	no	no	INTJ
ecletica-1594	154	2	yes	yes	INTJ
ecletica-1594	154	3	–	–	PUNCT
ecletica-1594	154	4	6.95	6.95	NUM
ecletica-1594	154	5	naj	naj	NOUN
ecletica-1594	154	6	low	low	NOUN
ecletica-1594	155	1	no	no	INTJ
ecletica-1594	156	1	no	no	INTJ
ecletica-1594	157	1	no	no	INTJ
ecletica-1594	158	1	yes	yes	INTJ
ecletica-1594	159	1	yes	yes	INTJ
ecletica-1594	160	1	no	no	INTJ
ecletica-1594	160	2	yes	yes	INTJ
ecletica-1594	160	3	–	–	PUNCT
ecletica-1594	160	4	7.12	7.12	NUM
ecletica-1594	160	5	nak	nak	NOUN
ecletica-1594	160	6	low	low	ADJ
ecletica-1594	161	1	no	no	INTJ
ecletica-1594	161	2	no	no	INTJ
ecletica-1594	162	1	no	no	INTJ
ecletica-1594	163	1	yes	yes	INTJ
ecletica-1594	164	1	yes	yes	INTJ
ecletica-1594	165	1	no	no	INTJ
ecletica-1594	165	2	yes	yes	INTJ
ecletica-1594	165	3	–	–	PUNCT
ecletica-1594	165	4	6.95	6.95	NUM
ecletica-1594	165	5	nal	nal	NOUN
ecletica-1594	165	6	low	low	NOUN
ecletica-1594	166	1	no	no	INTJ
ecletica-1594	166	2	yes	yes	INTJ
ecletica-1594	167	1	no	no	INTJ
ecletica-1594	167	2	no	no	INTJ
ecletica-1594	168	1	no	no	INTJ
ecletica-1594	168	2	no	no	INTJ
ecletica-1594	168	3	yes	yes	INTJ
ecletica-1594	168	4	–	–	PUNCT
ecletica-1594	168	5	7.25	7.25	NUM
ecletica-1594	168	6	nam	nam	NOUN
ecletica-1594	168	7	low	low	INTJ
ecletica-1594	169	1	no	no	INTJ
ecletica-1594	170	1	yes	yes	INTJ
ecletica-1594	171	1	yes	yes	INTJ
ecletica-1594	172	1	no	no	INTJ
ecletica-1594	172	2	no	no	INTJ
ecletica-1594	173	1	no	no	INTJ
ecletica-1594	173	2	yes	yes	INTJ
ecletica-1594	173	3	–	–	PUNCT
ecletica-1594	173	4	7.45	7.45	NUM
ecletica-1594	173	5	nan	nan	NOUN
ecletica-1594	173	6	low	low	INTJ
ecletica-1594	174	1	no	no	INTJ
ecletica-1594	174	2	yes	yes	INTJ
ecletica-1594	175	1	no	no	INTJ
ecletica-1594	175	2	no	no	INTJ
ecletica-1594	176	1	no	no	INTJ
ecletica-1594	176	2	no	no	INTJ
ecletica-1594	177	1	yes	yes	INTJ
ecletica-1594	177	2	–	–	PUNCT
ecletica-1594	177	3	7.76	7.76	NUM
ecletica-1594	177	4	5ad	5ad	NOUN
ecletica-1594	177	5	high	high	ADJ
ecletica-1594	178	1	no	no	INTJ
ecletica-1594	178	2	yes	yes	INTJ
ecletica-1594	179	1	no	no	INTJ
ecletica-1594	179	2	no	no	INTJ
ecletica-1594	180	1	no	no	INTJ
ecletica-1594	180	2	no	no	INTJ
ecletica-1594	180	3	no	no	INTJ
ecletica-1594	180	4	–	–	PUNCT
ecletica-1594	180	5	8.63	8.63	NUM
ecletica-1594	180	6	penicillin	penicillin	NOUN
ecletica-1594	180	7	high	high	ADV
ecletica-1594	181	1	no	no	INTJ
ecletica-1594	181	2	no	no	INTJ
ecletica-1594	181	3	no	no	INTJ
ecletica-1594	181	4	no	no	INTJ
ecletica-1594	181	5	no	no	INTJ
ecletica-1594	181	6	no	no	INTJ
ecletica-1594	181	7	no	no	INTJ
ecletica-1594	181	8	–	–	PUNCT
ecletica-1594	181	9	6.75	6.75	NUM
ecletica-1594	181	10	sulfameth	sulfameth	NOUN
ecletica-1594	181	11	oxazole	oxazole	NOUN
ecletica-1594	181	12	high	high	ADV
ecletica-1594	182	1	no	no	INTJ
ecletica-1594	182	2	no	no	INTJ
ecletica-1594	182	3	no	no	INTJ
ecletica-1594	182	4	no	no	INTJ
ecletica-1594	182	5	no	no	INTJ
ecletica-1594	182	6	no	no	INTJ
ecletica-1594	182	7	no	no	INTJ
ecletica-1594	182	8	–	–	PUNCT
ecletica-1594	182	9	6.93	6.93	NUM
ecletica-1594	182	10	source	source	NOUN
ecletica-1594	182	11	:	:	PUNCT
ecletica-1594	182	12	elaborated	elaborate	VERB
ecletica-1594	182	13	by	by	ADP
ecletica-1594	182	14	the	the	DET
ecletica-1594	182	15	authors	author	NOUN
ecletica-1594	182	16	.	.	PUNCT
ecletica-1594	183	1	4	4	X
ecletica-1594	183	2	.	.	X
ecletica-1594	183	3	conclusions	conclusion	NOUN
ecletica-1594	183	4	this	this	DET
ecletica-1594	183	5	study	study	NOUN
ecletica-1594	183	6	emphasized	emphasize	VERB
ecletica-1594	183	7	an	an	DET
ecletica-1594	183	8	in	in	ADP
ecletica-1594	183	9	-	-	PUNCT
ecletica-1594	183	10	silico	silico	NOUN
ecletica-1594	183	11	assessment	assessment	NOUN
ecletica-1594	183	12	of	of	ADP
ecletica-1594	183	13	antibacterial	antibacterial	ADJ
ecletica-1594	183	14	activities	activity	NOUN
ecletica-1594	183	15	of	of	ADP
ecletica-1594	183	16	sulfamidophosponate	sulfamidophosponate	VERB
ecletica-1594	183	17	derivatives	derivative	NOUN
ecletica-1594	183	18	as	as	SCONJ
ecletica-1594	183	19	compared	compare	VERB
ecletica-1594	183	20	with	with	ADP
ecletica-1594	183	21	standard	standard	ADJ
ecletica-1594	183	22	drugs	drug	NOUN
ecletica-1594	183	23	(	(	PUNCT
ecletica-1594	183	24	penicillin	penicillin	NOUN
ecletica-1594	183	25	and	and	CCONJ
ecletica-1594	183	26	sulfamethoxazole	sulfamethoxazole	NOUN
ecletica-1594	183	27	)	)	PUNCT
ecletica-1594	183	28	against	against	ADP
ecletica-1594	183	29	target	target	NOUN
ecletica-1594	183	30	proteins	protein	NOUN
ecletica-1594	183	31	of	of	ADP
ecletica-1594	183	32	staphylococcus	staphylococcus	NOUN
ecletica-1594	183	33	aureus	aureus	NOUN
ecletica-1594	183	34	via	via	ADP
ecletica-1594	183	35	molecular	molecular	ADJ
ecletica-1594	183	36	docking	docking	NOUN
ecletica-1594	183	37	and	and	CCONJ
ecletica-1594	183	38	admet	admet	PROPN
ecletica-1594	183	39	prediction	prediction	NOUN
ecletica-1594	183	40	.	.	PUNCT
ecletica-1594	184	1	in	in	ADP
ecletica-1594	184	2	this	this	DET
ecletica-1594	184	3	study	study	NOUN
ecletica-1594	184	4	,	,	PUNCT
ecletica-1594	184	5	compounds	compound	VERB
ecletica-1594	184	6	nah	nah	INTJ
ecletica-1594	184	7	,	,	PUNCT
ecletica-1594	184	8	nal	nal	PROPN
ecletica-1594	184	9	,	,	PUNCT
ecletica-1594	184	10	nai	nai	NOUN
ecletica-1594	184	11	and	and	CCONJ
ecletica-1594	184	12	naj	naj	PROPN
ecletica-1594	184	13	exhibited	exhibit	VERB
ecletica-1594	184	14	stronger	strong	ADJ
ecletica-1594	184	15	affinities	affinity	NOUN
ecletica-1594	184	16	than	than	ADP
ecletica-1594	184	17	the	the	DET
ecletica-1594	184	18	standard	standard	NOUN
ecletica-1594	184	19	(	(	PUNCT
ecletica-1594	184	20	penicillin	penicillin	NOUN
ecletica-1594	184	21	)	)	PUNCT
ecletica-1594	184	22	against	against	ADP
ecletica-1594	184	23	blai	blai	PROPN
ecletica-1594	184	24	repressor	repressor	NOUN
ecletica-1594	184	25	in	in	ADP
ecletica-1594	184	26	complex	complex	NOUN
ecletica-1594	184	27	with	with	ADP
ecletica-1594	184	28	dna	dna	PROPN
ecletica-1594	184	29	(	(	PUNCT
ecletica-1594	184	30	pdb	pdb	PROPN
ecletica-1594	184	31	i	i	PROPN
ecletica-1594	184	32	d	d	PROPN
ecletica-1594	184	33	:	:	PUNCT
ecletica-1594	184	34	1xsd	1xsd	NUM
ecletica-1594	184	35	)	)	PUNCT
ecletica-1594	184	36	,	,	PUNCT
ecletica-1594	184	37	suggesting	suggest	VERB
ecletica-1594	184	38	a	a	DET
ecletica-1594	184	39	better	well	ADJ
ecletica-1594	184	40	inhibitory	inhibitory	ADJ
ecletica-1594	184	41	potential	potential	NOUN
ecletica-1594	184	42	than	than	ADP
ecletica-1594	184	43	the	the	DET
ecletica-1594	184	44	standard	standard	ADJ
ecletica-1594	184	45	drug	drug	NOUN
ecletica-1594	184	46	.	.	PUNCT
ecletica-1594	185	1	furthermore	furthermore	ADV
ecletica-1594	185	2	,	,	PUNCT
ecletica-1594	185	3	compounds	compound	VERB
ecletica-1594	185	4	nah	nah	INTJ
ecletica-1594	185	5	,	,	PUNCT
ecletica-1594	185	6	nai	nai	PROPN
ecletica-1594	185	7	,	,	PUNCT
ecletica-1594	185	8	naj	naj	NOUN
ecletica-1594	185	9	,	,	PUNCT
ecletica-1594	185	10	nal	nal	NOUN
ecletica-1594	185	11	,	,	PUNCT
ecletica-1594	185	12	nam	nam	PROPN
ecletica-1594	185	13	,	,	PUNCT
ecletica-1594	185	14	nan	nan	PROPN
ecletica-1594	185	15	and	and	CCONJ
ecletica-1594	185	16	5ad	5ad	PROPN
ecletica-1594	185	17	potentially	potentially	ADV
ecletica-1594	185	18	inhibit	inhibit	VERB
ecletica-1594	185	19	4wk3	4wk3	NUM
ecletica-1594	185	20	than	than	ADP
ecletica-1594	185	21	the	the	DET
ecletica-1594	185	22	standard	standard	ADJ
ecletica-1594	185	23	drug	drug	NOUN
ecletica-1594	185	24	(	(	PUNCT
ecletica-1594	185	25	penicillin	penicillin	NOUN
ecletica-1594	185	26	)	)	PUNCT
ecletica-1594	185	27	.	.	PUNCT
ecletica-1594	186	1	these	these	DET
ecletica-1594	186	2	compounds	compound	NOUN
ecletica-1594	186	3	could	could	AUX
ecletica-1594	186	4	be	be	AUX
ecletica-1594	186	5	inhibitors	inhibitor	NOUN
ecletica-1594	186	6	with	with	ADP
ecletica-1594	186	7	potential	potential	NOUN
ecletica-1594	186	8	for	for	ADP
ecletica-1594	186	9	treating	treat	VERB
ecletica-1594	186	10	bacterial	bacterial	ADJ
ecletica-1594	186	11	infection	infection	NOUN
ecletica-1594	186	12	.	.	PUNCT
ecletica-1594	187	1	additionally	additionally	ADV
ecletica-1594	187	2	,	,	PUNCT
ecletica-1594	187	3	the	the	DET
ecletica-1594	187	4	admet	admet	PROPN
ecletica-1594	187	5	results	result	NOUN
ecletica-1594	187	6	revealed	reveal	VERB
ecletica-1594	187	7	that	that	SCONJ
ecletica-1594	187	8	compounds	compound	NOUN
ecletica-1594	187	9	nag	nag	VERB
ecletica-1594	187	10	,	,	PUNCT
ecletica-1594	187	11	nae	nae	PROPN
ecletica-1594	187	12	,	,	PUNCT
ecletica-1594	187	13	nah	nah	INTJ
ecletica-1594	187	14	,	,	PUNCT
ecletica-1594	187	15	and	and	CCONJ
ecletica-1594	187	16	nak	nak	NOUN
ecletica-1594	187	17	have	have	VERB
ecletica-1594	187	18	attractive	attractive	ADJ
ecletica-1594	187	19	pharmacokinetic	pharmacokinetic	ADJ
ecletica-1594	187	20	properties	property	NOUN
ecletica-1594	187	21	.	.	PUNCT
ecletica-1594	188	1	in	in	ADP
ecletica-1594	188	2	general	general	ADJ
ecletica-1594	188	3	,	,	PUNCT
ecletica-1594	188	4	this	this	DET
ecletica-1594	188	5	study	study	NOUN
ecletica-1594	188	6	demonstrated	demonstrate	VERB
ecletica-1594	188	7	that	that	SCONJ
ecletica-1594	188	8	compounds	compounds	PROPN
ecletica-1594	188	9	naf	naf	PROPN
ecletica-1594	188	10	,	,	PUNCT
ecletica-1594	188	11	nai	nai	PROPN
ecletica-1594	188	12	,	,	PUNCT
ecletica-1594	188	13	nak	nak	PROPN
ecletica-1594	188	14	and	and	CCONJ
ecletica-1594	188	15	nan	nan	PROPN
ecletica-1594	188	16	could	could	AUX
ecletica-1594	188	17	be	be	AUX
ecletica-1594	188	18	potential	potential	ADJ
ecletica-1594	188	19	inhibitors	inhibitor	NOUN
ecletica-1594	188	20	against	against	ADP
ecletica-1594	188	21	staphylococcus	staphylococcus	NOUN
ecletica-1594	188	22	aureus	aureus	NOUN
ecletica-1594	188	23	,	,	PUNCT
ecletica-1594	188	24	and	and	CCONJ
ecletica-1594	188	25	they	they	PRON
ecletica-1594	188	26	possess	possess	VERB
ecletica-1594	188	27	good	good	ADJ
ecletica-1594	188	28	pharmacokinetic	pharmacokinetic	ADJ
ecletica-1594	188	29	properties	property	NOUN
ecletica-1594	188	30	,	,	PUNCT
ecletica-1594	188	31	which	which	PRON
ecletica-1594	188	32	are	be	AUX
ecletica-1594	188	33	probable	probable	ADJ
ecletica-1594	188	34	for	for	ADP
ecletica-1594	188	35	drug	drug	NOUN
ecletica-1594	188	36	discovery	discovery	NOUN
ecletica-1594	188	37	.	.	PUNCT
ecletica-1594	189	1	authors	author	NOUN
ecletica-1594	189	2	’	’	PART
ecletica-1594	189	3	contribution	contribution	NOUN
ecletica-1594	189	4	conceptualization	conceptualization	NOUN
ecletica-1594	189	5	:	:	PUNCT
ecletica-1594	189	6	abimbola	abimbola	PROPN
ecletica-1594	189	7	modupe	modupe	PROPN
ecletica-1594	189	8	olatunde	olatunde	PROPN
ecletica-1594	189	9	,	,	PUNCT
ecletica-1594	189	10	kehinde	kehinde	PROPN
ecletica-1594	189	11	gabriel	gabriel	PROPN
ecletica-1594	189	12	obiyenwa	obiyenwa	PROPN
ecletica-1594	189	13	;	;	PUNCT
ecletica-1594	189	14	data	datum	NOUN
ecletica-1594	189	15	curation	curation	NOUN
ecletica-1594	189	16	:	:	PUNCT
ecletica-1594	189	17	nathaniel	nathaniel	PROPN
ecletica-1594	189	18	oladoye	oladoye	PROPN
ecletica-1594	189	19	olatunji	olatunji	PROPN
ecletica-1594	189	20	;	;	PUNCT
ecletica-1594	189	21	kehinde	kehinde	PROPN
ecletica-1594	189	22	gabriel	gabriel	PROPN
ecletica-1594	189	23	obiyenwa	obiyenwa	PROPN
ecletica-1594	189	24	;	;	PUNCT
ecletica-1594	189	25	formal	formal	ADJ
ecletica-1594	189	26	analysis	analysis	NOUN
ecletica-1594	189	27	:	:	PUNCT
ecletica-1594	189	28	nathaniel	nathaniel	PROPN
ecletica-1594	189	29	oladoye	oladoye	PROPN
ecletica-1594	189	30	olatunji	olatunji	PROPN
ecletica-1594	189	31	;	;	PUNCT
ecletica-1594	189	32	kehinde	kehinde	PROPN
ecletica-1594	189	33	gabriel	gabriel	PROPN
ecletica-1594	189	34	obiyenwa	obiyenwa	PROPN
ecletica-1594	189	35	;	;	PUNCT
ecletica-1594	189	36	funding	funding	NOUN
ecletica-1594	189	37	acquisition	acquisition	NOUN
ecletica-1594	189	38	:	:	PUNCT
ecletica-1594	189	39	abimbola	abimbola	PROPN
ecletica-1594	189	40	modupe	modupe	PROPN
ecletica-1594	189	41	olatunde	olatunde	PROPN
ecletica-1594	189	42	,	,	PUNCT
ecletica-1594	189	43	kehinde	kehinde	PROPN
ecletica-1594	189	44	gabriel	gabriel	PROPN
ecletica-1594	189	45	obiyenwa	obiyenwa	PROPN
ecletica-1594	189	46	;	;	PUNCT
ecletica-1594	189	47	investigation	investigation	NOUN
ecletica-1594	189	48	:	:	PUNCT
ecletica-1594	189	49	tofunmi	tofunmi	PROPN
ecletica-1594	189	50	emmanuel	emmanuel	PROPN
ecletica-1594	189	51	oladuji	oladuji	PROPN
ecletica-1594	189	52	,	,	PUNCT
ecletica-1594	189	53	dayo	dayo	NOUN
ecletica-1594	189	54	felix	felix	PROPN
ecletica-1594	189	55	latona	latona	PROPN
ecletica-1594	189	56	;	;	PUNCT
ecletica-1594	189	57	methodology	methodology	NOUN
ecletica-1594	189	58	:	:	PUNCT
ecletica-1594	189	59	abimbola	abimbola	PROPN
ecletica-1594	189	60	modupe	modupe	PROPN
ecletica-1594	189	61	olatunde	olatunde	PROPN
ecletica-1594	189	62	,	,	PUNCT
ecletica-1594	189	63	kehinde	kehinde	PROPN
ecletica-1594	189	64	gabriel	gabriel	PROPN
ecletica-1594	189	65	obiyenwa	obiyenwa	PROPN
ecletica-1594	189	66	;	;	PUNCT
ecletica-1594	189	67	project	project	NOUN
ecletica-1594	189	68	administration	administration	NOUN
ecletica-1594	189	69	:	:	PUNCT
ecletica-1594	189	70	abel	abel	PROPN
ecletica-1594	189	71	kolawole	kolawole	PROPN
ecletica-1594	189	72	oyebamiji	oyebamiji	PROPN
ecletica-1594	189	73	;	;	PUNCT
ecletica-1594	189	74	banjo	banjo	NOUN
ecletica-1594	189	75	semire	semire	NOUN
ecletica-1594	189	76	;	;	PUNCT
ecletica-1594	189	77	resources	resource	NOUN
ecletica-1594	189	78	:	:	PUNCT
ecletica-1594	189	79	tofunmi	tofunmi	PROPN
ecletica-1594	189	80	emmanuel	emmanuel	PROPN
ecletica-1594	189	81	oladuji	oladuji	PROPN
ecletica-1594	189	82	,	,	PUNCT
ecletica-1594	189	83	dayo	dayo	NOUN
ecletica-1594	189	84	felix	felix	PROPN
ecletica-1594	189	85	latona	latona	PROPN
ecletica-1594	189	86	;	;	PUNCT
ecletica-1594	189	87	software	software	NOUN
ecletica-1594	189	88	:	:	PUNCT
ecletica-1594	189	89	abel	abel	PROPN
ecletica-1594	189	90	kolawole	kolawole	PROPN
ecletica-1594	189	91	oyebamiji	oyebamiji	PROPN
ecletica-1594	189	92	;	;	PUNCT
ecletica-1594	189	93	banjo	banjo	NOUN
ecletica-1594	189	94	semire	semire	NOUN
ecletica-1594	189	95	;	;	PUNCT
ecletica-1594	189	96	supervision	supervision	NOUN
ecletica-1594	189	97	:	:	PUNCT
ecletica-1594	189	98	abel	abel	PROPN
ecletica-1594	189	99	kolawole	kolawole	PROPN
ecletica-1594	189	100	oyebamiji	oyebamiji	PROPN
ecletica-1594	189	101	;	;	PUNCT
ecletica-1594	189	102	banjo	banjo	NOUN
ecletica-1594	189	103	semire	semire	NOUN
ecletica-1594	189	104	;	;	PUNCT
ecletica-1594	189	105	validation	validation	NOUN
ecletica-1594	189	106	:	:	PUNCT
ecletica-1594	189	107	tofunmi	tofunmi	PROPN
ecletica-1594	189	108	emmanuel	emmanuel	PROPN
ecletica-1594	189	109	oladuji	oladuji	PROPN
ecletica-1594	189	110	,	,	PUNCT
ecletica-1594	189	111	dayo	dayo	NOUN
ecletica-1594	189	112	felix	felix	PROPN
ecletica-1594	189	113	latona	latona	PROPN
ecletica-1594	189	114	;	;	PUNCT
ecletica-1594	189	115	visualization	visualization	NOUN
ecletica-1594	189	116	:	:	PUNCT
ecletica-1594	189	117	abel	abel	PROPN
ecletica-1594	189	118	kolawole	kolawole	PROPN
ecletica-1594	189	119	oyebamiji	oyebamiji	PROPN
ecletica-1594	189	120	;	;	PUNCT
ecletica-1594	189	121	banjo	banjo	NOUN
ecletica-1594	189	122	semire	semire	NOUN
ecletica-1594	189	123	;	;	PUNCT
ecletica-1594	189	124	writing	write	VERB
ecletica-1594	189	125	–	–	PUNCT
ecletica-1594	189	126	original	original	ADJ
ecletica-1594	189	127	draft	draft	NOUN
ecletica-1594	189	128	:	:	PUNCT
ecletica-1594	189	129	abel	abel	PROPN
ecletica-1594	189	130	kolawole	kolawole	PROPN
ecletica-1594	189	131	oyebamiji	oyebamiji	PROPN
ecletica-1594	189	132	;	;	PUNCT
ecletica-1594	189	133	banjo	banjo	NOUN
ecletica-1594	189	134	semire	semire	NOUN
ecletica-1594	189	135	;	;	PUNCT
ecletica-1594	189	136	writing	write	VERB
ecletica-1594	189	137	–	–	PUNCT
ecletica-1594	189	138	review	review	NOUN
ecletica-1594	189	139	&	&	CCONJ
ecletica-1594	189	140	editing	editing	PROPN
ecletica-1594	189	141	:	:	PUNCT
ecletica-1594	189	142	abel	abel	PROPN
ecletica-1594	189	143	kolawole	kolawole	PROPN
ecletica-1594	189	144	oyebamiji	oyebamiji	PROPN
ecletica-1594	189	145	;	;	PUNCT
ecletica-1594	189	146	banjo	banjo	NOUN
ecletica-1594	189	147	semire	semire	NOUN
ecletica-1594	189	148	.	.	PUNCT
ecletica-1594	190	1	data	datum	NOUN
ecletica-1594	190	2	availability	availability	NOUN
ecletica-1594	190	3	statement	statement	NOUN
ecletica-1594	190	4	all	all	DET
ecletica-1594	190	5	data	datum	NOUN
ecletica-1594	190	6	sets	set	NOUN
ecletica-1594	190	7	were	be	AUX
ecletica-1594	190	8	generated	generate	VERB
ecletica-1594	190	9	or	or	CCONJ
ecletica-1594	190	10	analyzed	analyze	VERB
ecletica-1594	190	11	in	in	ADP
ecletica-1594	190	12	the	the	DET
ecletica-1594	190	13	current	current	ADJ
ecletica-1594	190	14	study	study	NOUN
ecletica-1594	190	15	.	.	PUNCT
ecletica-1594	191	1	funding	funding	NOUN
ecletica-1594	191	2	not	not	PART
ecletica-1594	191	3	applicable	applicable	ADJ
ecletica-1594	191	4	.	.	PUNCT
ecletica-1594	192	1	acknowledgments	acknowledgment	NOUN
ecletica-1594	192	2	not	not	PART
ecletica-1594	192	3	applicable	applicable	ADJ
ecletica-1594	192	4	.	.	PUNCT
ecletica-1594	193	1	conflict	conflict	NOUN
ecletica-1594	193	2	of	of	ADP
ecletica-1594	193	3	interest	interest	NOUN
ecletica-1594	193	4	the	the	DET
ecletica-1594	193	5	authors	author	NOUN
ecletica-1594	193	6	declare	declare	VERB
ecletica-1594	193	7	that	that	SCONJ
ecletica-1594	193	8	there	there	PRON
ecletica-1594	193	9	is	be	VERB
ecletica-1594	193	10	no	no	DET
ecletica-1594	193	11	conflict	conflict	NOUN
ecletica-1594	193	12	of	of	ADP
ecletica-1594	193	13	interest	interest	NOUN
ecletica-1594	193	14	.	.	PUNCT
ecletica-1594	194	1	references	reference	NOUN
ecletica-1594	194	2	adegbola	adegbola	PROPN
ecletica-1594	194	3	,	,	PUNCT
ecletica-1594	194	4	a.	a.	PROPN
ecletica-1594	194	5	e.	e.	PROPN
ecletica-1594	194	6	;	;	PUNCT
ecletica-1594	194	7	fadahunsi	fadahunsi	PROPN
ecletica-1594	194	8	,	,	PUNCT
ecletica-1594	194	9	o.	o.	PROPN
ecletica-1594	194	10	s.	s.	PROPN
ecletica-1594	194	11	;	;	PUNCT
ecletica-1594	194	12	alausa	alausa	NOUN
ecletica-1594	194	13	,	,	PUNCT
ecletica-1594	194	14	a.	a.	NOUN
ecletica-1594	194	15	;	;	PUNCT
ecletica-1594	194	16	abijo	abijo	PROPN
ecletica-1594	194	17	,	,	PUNCT
ecletica-1594	194	18	a.	a.	PROPN
ecletica-1594	194	19	z.	z.	PROPN
ecletica-1594	194	20	;	;	PUNCT
ecletica-1594	194	21	balogun	balogun	VERB
ecletica-1594	194	22	,	,	PUNCT
ecletica-1594	194	23	t.	t.	NOUN
ecletica-1594	194	24	a.	a.	NOUN
ecletica-1594	194	25	;	;	PUNCT
ecletica-1594	194	26	aderibigbe	aderibigbe	NOUN
ecletica-1594	194	27	,	,	PUNCT
ecletica-1594	194	28	t.	t.	PROPN
ecletica-1594	194	29	s.	s.	PROPN
ecletica-1594	194	30	;	;	PUNCT
ecletica-1594	194	31	semire	semire	PROPN
ecletica-1594	194	32	,	,	PUNCT
ecletica-1594	194	33	b.	b.	PROPN
ecletica-1594	194	34	;	;	PUNCT
ecletica-1594	194	35	adegbola	adegbola	PROPN
ecletica-1594	194	36	,	,	PUNCT
ecletica-1594	195	1	p.	p.	PROPN
ecletica-1594	195	2	i.	i.	PROPN
ecletica-1594	196	1	computational	computational	ADJ
ecletica-1594	196	2	prediction	prediction	NOUN
ecletica-1594	196	3	of	of	ADP
ecletica-1594	196	4	nimbanal	nimbanal	ADJ
ecletica-1594	196	5	as	as	ADP
ecletica-1594	196	6	potential	potential	ADJ
ecletica-1594	196	7	antagonist	antagonist	NOUN
ecletica-1594	196	8	of	of	ADP
ecletica-1594	196	9	respiratory	respiratory	ADJ
ecletica-1594	196	10	syndrome	syndrome	NOUN
ecletica-1594	196	11	coronavirus	coronavirus	NOUN
ecletica-1594	196	12	.	.	PUNCT
ecletica-1594	197	1	inform	inform	NOUN
ecletica-1594	197	2	.	.	PUNCT
ecletica-1594	198	1	med	med	PROPN
ecletica-1594	198	2	.	.	PUNCT
ecletica-1594	199	1	unlocked	unlock	VERB
ecletica-1594	199	2	.	.	PUNCT
ecletica-1594	200	1	2021a	2021a	NUM
ecletica-1594	200	2	,	,	PUNCT
ecletica-1594	200	3	24	24	NUM
ecletica-1594	200	4	,	,	PUNCT
ecletica-1594	200	5	100617	100617	NUM
ecletica-1594	200	6	.	.	PUNCT
ecletica-1594	201	1	https://doi.org/10.1016/j.imu.2021.100617	https://doi.org/10.1016/j.imu.2021.100617	PROPN
ecletica-1594	201	2	adegbola	adegbola	PROPN
ecletica-1594	201	3	,	,	PUNCT
ecletica-1594	201	4	p.	p.	NOUN
ecletica-1594	201	5	i.	i.	PROPN
ecletica-1594	201	6	;	;	PUNCT
ecletica-1594	201	7	semire	semire	PROPN
ecletica-1594	201	8	,	,	PUNCT
ecletica-1594	201	9	b.	b.	PROPN
ecletica-1594	201	10	;	;	PUNCT
ecletica-1594	201	11	fadahunsi	fadahunsi	PROPN
ecletica-1594	201	12	,	,	PUNCT
ecletica-1594	201	13	o.	o.	PROPN
ecletica-1594	201	14	s.	s.	PROPN
ecletica-1594	201	15	;	;	PUNCT
ecletica-1594	201	16	adegoke	adegoke	VERB
ecletica-1594	201	17	,	,	PUNCT
ecletica-1594	201	18	a.	a.	PROPN
ecletica-1594	201	19	e.	e.	PROPN
ecletica-1594	201	20	molecular	molecular	PROPN
ecletica-1594	201	21	docking	docking	PROPN
ecletica-1594	201	22	and	and	CCONJ
ecletica-1594	201	23	admet	admet	PROPN
ecletica-1594	201	24	studies	study	NOUN
ecletica-1594	201	25	of	of	ADP
ecletica-1594	201	26	allium	allium	NOUN
ecletica-1594	201	27	cepa	cepa	NOUN
ecletica-1594	201	28	,	,	PUNCT
ecletica-1594	201	29	azadirachta	azadirachta	VERB
ecletica-1594	201	30	indica	indica	PROPN
ecletica-1594	201	31	and	and	CCONJ
ecletica-1594	201	32	xylopia	xylopia	PROPN
ecletica-1594	201	33	aethiopica	aethiopica	PROPN
ecletica-1594	201	34	isolates	isolate	NOUN
ecletica-1594	201	35	as	as	ADP
ecletica-1594	201	36	potential	potential	ADJ
ecletica-1594	201	37	anti	anti	ADJ
ecletica-1594	201	38	-	-	ADJ
ecletica-1594	201	39	viral	viral	ADJ
ecletica-1594	201	40	drugs	drug	NOUN
ecletica-1594	201	41	for	for	ADP
ecletica-1594	201	42	covid-19	covid-19	PROPN
ecletica-1594	201	43	.	.	PROPN
ecletica-1594	201	44	virus	virus	PROPN
ecletica-1594	201	45	dis	dis	PROPN
ecletica-1594	201	46	.	.	PUNCT
ecletica-1594	202	1	2021b	2021b	NUM
ecletica-1594	202	2	,	,	PUNCT
ecletica-1594	202	3	32	32	NUM
ecletica-1594	202	4	,	,	PUNCT
ecletica-1594	202	5	85	85	NUM
ecletica-1594	202	6	-	-	SYM
ecletica-1594	202	7	97	97	NUM
ecletica-1594	202	8	.	.	PUNCT
ecletica-1594	203	1	https://doi.org/10.1007/s13337-021-00682-7	https://doi.org/10.1007/s13337-021-00682-7	NUM
ecletica-1594	203	2	adepoju	adepoju	PROPN
ecletica-1594	203	3	a.	a.	PROPN
ecletica-1594	203	4	j.	j.	PROPN
ecletica-1594	203	5	;	;	PUNCT
ecletica-1594	203	6	latona	latona	PROPN
ecletica-1594	203	7	d.	d.	PROPN
ecletica-1594	203	8	f.	f.	PROPN
ecletica-1594	203	9	;	;	PUNCT
ecletica-1594	203	10	oluwafemi	oluwafemi	NOUN
ecletica-1594	203	11	gbenga	gbenga	VERB
ecletica-1594	203	12	olafare	olafare	NOUN
ecletica-1594	203	13	o.	o.	PROPN
ecletica-1594	203	14	g.	g.	PROPN
ecletica-1594	203	15	;	;	PUNCT
ecletica-1594	203	16	oyebamiji	oyebamiji	PROPN
ecletica-1594	203	17	a.	a.	PROPN
ecletica-1594	203	18	k.	k.	PROPN
ecletica-1594	203	19	;	;	PUNCT
ecletica-1594	203	20	misbaudeen	misbaudeen	PROPN
ecletica-1594	203	21	abdul	abdul	PROPN
ecletica-1594	203	22	-	-	PUNCT
ecletica-1594	203	23	hammed	ham	VERB
ecletica-1594	203	24	m.	m.	NOUN
ecletica-1594	203	25	;	;	PUNCT
ecletica-1594	203	26	semire	semire	NOUN
ecletica-1594	203	27	b.	b.	PROPN
ecletica-1594	204	1	molecular	molecular	ADJ
ecletica-1594	204	2	docking	docking	NOUN
ecletica-1594	204	3	and	and	CCONJ
ecletica-1594	204	4	pharmacokinetics	pharmacokinetic	NOUN
ecletica-1594	204	5	studies	study	NOUN
ecletica-1594	204	6	of	of	ADP
ecletica-1594	204	7	curcuma	curcuma	PROPN
ecletica-1594	204	8	longa	longa	NOUN
ecletica-1594	204	9	(	(	PUNCT
ecletica-1594	204	10	curcumin	curcumin	NOUN
ecletica-1594	204	11	)	)	PUNCT
ecletica-1594	204	12	potency	potency	NOUN
ecletica-1594	204	13	against	against	ADP
ecletica-1594	204	14	ebola	ebola	PROPN
ecletica-1594	204	15	virus	virus	NOUN
ecletica-1594	204	16	.	.	PUNCT
ecletica-1594	205	1	ovidius	ovidius	PROPN
ecletica-1594	205	2	university	university	NOUN
ecletica-1594	205	3	annals	annals	NOUN
ecletica-1594	205	4	of	of	ADP
ecletica-1594	205	5	chemistry	chemistry	NOUN
ecletica-1594	205	6	.	.	PUNCT
ecletica-1594	206	1	2022	2022	NUM
ecletica-1594	206	2	,	,	PUNCT
ecletica-1594	206	3	33	33	NUM
ecletica-1594	206	4	(	(	PUNCT
ecletica-1594	206	5	1	1	NUM
ecletica-1594	206	6	)	)	PUNCT
ecletica-1594	206	7	,	,	PUNCT
ecletica-1594	206	8	23–35	23–35	NUM
ecletica-1594	206	9	.	.	PUNCT
ecletica-1594	207	1	https://doi.org/10.2478/auoc-2022-0004	https://doi.org/10.2478/auoc-2022-0004	PROPN
ecletica-1594	207	2	arora	arora	PROPN
ecletica-1594	207	3	p.	p.	NOUN
ecletica-1594	207	4	;	;	PUNCT
ecletica-1594	207	5	arora	arora	PROPN
ecletica-1594	207	6	v.	v.	PROPN
ecletica-1594	207	7	;	;	PUNCT
ecletica-1594	207	8	lamba	lamba	PROPN
ecletica-1594	207	9	h.	h.	PROPN
ecletica-1594	207	10	;	;	PUNCT
ecletica-1594	207	11	wadhwa	wadhwa	PROPN
ecletica-1594	207	12	,	,	PUNCT
ecletica-1594	207	13	d.	d.	NOUN
ecletica-1594	207	14	importance	importance	NOUN
ecletica-1594	207	15	of	of	ADP
ecletica-1594	207	16	heterocylic	heterocylic	ADJ
ecletica-1594	207	17	chemistry	chemistry	NOUN
ecletica-1594	207	18	:	:	PUNCT
ecletica-1594	207	19	a	a	DET
ecletica-1594	207	20	review	review	NOUN
ecletica-1594	207	21	.	.	PUNCT
ecletica-1594	208	1	international	international	ADJ
ecletica-1594	208	2	journal	journal	PROPN
ecletica-1594	208	3	of	of	ADP
ecletica-1594	208	4	pharmaceutical	pharmaceutical	NOUN
ecletica-1594	208	5	science	science	NOUN
ecletica-1594	208	6	.	.	PUNCT
ecletica-1594	209	1	2012	2012	NUM
ecletica-1594	209	2	,	,	PUNCT
ecletica-1594	209	3	3	3	NUM
ecletica-1594	209	4	(	(	PUNCT
ecletica-1594	209	5	9	9	NUM
ecletica-1594	209	6	)	)	PUNCT
ecletica-1594	209	7	,	,	PUNCT
ecletica-1594	209	8	2947–2954	2947–2954	NUM
ecletica-1594	209	9	.	.	PUNCT
ecletica-1594	209	10	asibor	asibor	PROPN
ecletica-1594	209	11	,	,	PUNCT
ecletica-1594	209	12	y.	y.	PROPN
ecletica-1594	209	13	e.	e.	PROPN
ecletica-1594	209	14	;	;	PUNCT
ecletica-1594	209	15	oyebamiji	oyebamiji	PROPN
ecletica-1594	209	16	,	,	PUNCT
ecletica-1594	209	17	a.	a.	PROPN
ecletica-1594	209	18	k.	k.	PROPN
ecletica-1594	209	19	;	;	PUNCT
ecletica-1594	210	1	latona	latona	PROPN
ecletica-1594	210	2	,	,	PUNCT
ecletica-1594	210	3	d.	d.	PROPN
ecletica-1594	210	4	f.	f.	PROPN
ecletica-1594	210	5	;	;	PUNCT
ecletica-1594	210	6	semire	semire	PROPN
ecletica-1594	210	7	,	,	PUNCT
ecletica-1594	210	8	b.	b.	PROPN
ecletica-1594	210	9	computational	computational	ADJ
ecletica-1594	210	10	screening	screening	NOUN
ecletica-1594	210	11	of	of	ADP
ecletica-1594	210	12	phytochemicals	phytochemical	NOUN
ecletica-1594	210	13	present	present	ADJ
ecletica-1594	210	14	in	in	ADP
ecletica-1594	210	15	some	some	DET
ecletica-1594	210	16	nigerian	nigerian	ADJ
ecletica-1594	210	17	medicinal	medicinal	ADJ
ecletica-1594	210	18	plants	plant	NOUN
ecletica-1594	210	19	against	against	ADP
ecletica-1594	210	20	sickle	sickle	NOUN
ecletica-1594	210	21	cell	cell	NOUN
ecletica-1594	210	22	disease	disease	NOUN
ecletica-1594	210	23	.	.	PUNCT
ecletica-1594	211	1	scientific	scientific	ADJ
ecletica-1594	211	2	reports	report	NOUN
ecletica-1594	211	3	.	.	PUNCT
ecletica-1594	212	1	2024	2024	NUM
ecletica-1594	212	2	,	,	PUNCT
ecletica-1594	212	3	14	14	NUM
ecletica-1594	212	4	(	(	PUNCT
ecletica-1594	212	5	1	1	NUM
ecletica-1594	212	6	)	)	PUNCT
ecletica-1594	212	7	,	,	PUNCT
ecletica-1594	212	8	26368	26368	NUM
ecletica-1594	212	9	.	.	PUNCT
ecletica-1594	213	1	https://doi.org/10.1038/s41598-024-75078-w	https://doi.org/10.1038/s41598-024-75078-w	NOUN
ecletica-1594	213	2	bazine	bazine	NOUN
ecletica-1594	213	3	,	,	PUNCT
ecletica-1594	213	4	i.	i.	PROPN
ecletica-1594	213	5	;	;	PUNCT
ecletica-1594	213	6	bendjedid	bendjedid	VERB
ecletica-1594	213	7	,	,	PUNCT
ecletica-1594	213	8	s.	s.	PROPN
ecletica-1594	213	9	;	;	PUNCT
ecletica-1594	213	10	boukhari	boukhari	PROPN
ecletica-1594	213	11	,	,	PUNCT
ecletica-1594	213	12	a.	a.	NOUN
ecletica-1594	213	13	potential	potential	ADJ
ecletica-1594	213	14	antibacterial	antibacterial	ADJ
ecletica-1594	213	15	and	and	CCONJ
ecletica-1594	213	16	antifungal	antifungal	ADJ
ecletica-1594	213	17	activities	activity	NOUN
ecletica-1594	213	18	of	of	ADP
ecletica-1594	213	19	novel	novel	ADJ
ecletica-1594	213	20	sulfamidophosphonate	sulfamidophosphonate	ADJ
ecletica-1594	213	21	derivatives	derivative	NOUN
ecletica-1594	213	22	bearing	bear	VERB
ecletica-1594	213	23	the	the	DET
ecletica-1594	213	24	quinoline	quinoline	NOUN
ecletica-1594	213	25	or	or	CCONJ
ecletica-1594	213	26	quinolone	quinolone	ADJ
ecletica-1594	213	27	moiety	moiety	NOUN
ecletica-1594	213	28	.	.	PUNCT
ecletica-1594	214	1	arch	arch	ADJ
ecletica-1594	214	2	pharm	pharm	PROPN
ecletica-1594	214	3	.	.	PUNCT
ecletica-1594	215	1	2020	2020	NUM
ecletica-1594	215	2	,	,	PUNCT
ecletica-1594	215	3	354	354	NUM
ecletica-1594	215	4	,	,	PUNCT
ecletica-1594	215	5	e2000291	e2000291	PROPN
ecletica-1594	215	6	.	.	PROPN
ecletica-1594	215	7	https://doi.org/10.1002/ardp.202000291	https://doi.org/10.1002/ardp.202000291	PROPN
ecletica-1594	215	8	bazine	bazine	PROPN
ecletica-1594	215	9	,	,	PUNCT
ecletica-1594	215	10	i.	i.	NOUN
ecletica-1594	215	11	;	;	PUNCT
ecletica-1594	215	12	cheraiet	cheraiet	PROPN
ecletica-1594	215	13	,	,	PUNCT
ecletica-1594	215	14	z.	z.	PROPN
ecletica-1594	215	15	;	;	PUNCT
ecletica-1594	215	16	bensegueni	bensegueni	PROPN
ecletica-1594	215	17	,	,	PUNCT
ecletica-1594	215	18	r.	r.	PROPN
ecletica-1594	215	19	;	;	PUNCT
ecletica-1594	215	20	bensouici	bensouici	PROPN
ecletica-1594	215	21	,	,	PUNCT
ecletica-1594	215	22	c.	c.	PROPN
ecletica-1594	215	23	;	;	PUNCT
ecletica-1594	215	24	boukhari	boukhari	ADJ
ecletica-1594	215	25	a.	a.	NOUN
ecletica-1594	215	26	antioxidant	antioxidant	NOUN
ecletica-1594	215	27	and	and	CCONJ
ecletica-1594	215	28	anticholinesterase	anticholinesterase	VERB
ecletica-1594	215	29	activities	activity	NOUN
ecletica-1594	215	30	of	of	ADP
ecletica-1594	215	31	novel	novel	ADJ
ecletica-1594	215	32	quinolineaminophosphonate	quinolineaminophosphonate	NOUN
ecletica-1594	215	33	derivatives	derivative	NOUN
ecletica-1594	215	34	.	.	PUNCT
ecletica-1594	216	1	journal	journal	NOUN
ecletica-1594	216	2	of	of	ADP
ecletica-1594	216	3	heterocyclic	heterocyclic	ADJ
ecletica-1594	216	4	chemistry	chemistry	NOUN
ecletica-1594	216	5	.	.	PUNCT
ecletica-1594	217	1	2020	2020	NUM
ecletica-1594	217	2	,	,	PUNCT
ecletica-1594	217	3	57	57	NUM
ecletica-1594	217	4	(	(	PUNCT
ecletica-1594	217	5	5	5	NUM
ecletica-1594	217	6	)	)	PUNCT
ecletica-1594	217	7	,	,	PUNCT
ecletica-1594	217	8	2139–2149	2139–2149	NUM
ecletica-1594	217	9	.	.	PUNCT
ecletica-1594	217	10	https://doi.org/10.1002/jhet.3933	https://doi.org/10.1002/jhet.3933	PROPN
ecletica-1594	217	11	becke	becke	NOUN
ecletica-1594	217	12	,	,	PUNCT
ecletica-1594	217	13	a.	a.	NOUN
ecletica-1594	217	14	density	density	NOUN
ecletica-1594	217	15	functional	functional	ADJ
ecletica-1594	217	16	thermochemistry	thermochemistry	NOUN
ecletica-1594	217	17	.	.	PUNCT
ecletica-1594	218	1	iii	iii	X
ecletica-1594	218	2	.	.	PUNCT
ecletica-1594	219	1	the	the	DET
ecletica-1594	219	2	role	role	NOUN
ecletica-1594	219	3	of	of	ADP
ecletica-1594	219	4	exact	exact	ADJ
ecletica-1594	219	5	exchange	exchange	NOUN
ecletica-1594	219	6	.	.	PUNCT
ecletica-1594	220	1	journal	journal	PROPN
ecletica-1594	220	2	of	of	ADP
ecletica-1594	220	3	physical	physical	ADJ
ecletica-1594	220	4	chemistry	chemistry	NOUN
ecletica-1594	220	5	.	.	PUNCT
ecletica-1594	221	1	1993	1993	NUM
ecletica-1594	221	2	,	,	PUNCT
ecletica-1594	221	3	98	98	NUM
ecletica-1594	221	4	(	(	PUNCT
ecletica-1594	221	5	7	7	NUM
ecletica-1594	221	6	)	)	PUNCT
ecletica-1594	221	7	,	,	PUNCT
ecletica-1594	221	8	5648–5652	5648–5652	NUM
ecletica-1594	221	9	.	.	PUNCT
ecletica-1594	222	1	https://doi.org/10.1063/1.464913	https://doi.org/10.1063/1.464913	PROPN
ecletica-1594	222	2	conrad	conrad	PROPN
ecletica-1594	222	3	,	,	PUNCT
ecletica-1594	222	4	j.	j.	PROPN
ecletica-1594	222	5	;	;	PUNCT
ecletica-1594	222	6	paras	paras	X
ecletica-1594	222	7	,	,	PUNCT
ecletica-1594	222	8	n.	n.	NOUN
ecletica-1594	222	9	a.	a.	PROPN
ecletica-1594	222	10	;	;	PUNCT
ecletica-1594	222	11	vaz	vaz	PROPN
ecletica-1594	222	12	,	,	PUNCT
ecletica-1594	222	13	r.	r.	PROPN
ecletica-1594	222	14	j.	j.	PROPN
ecletica-1594	222	15	model	model	PROPN
ecletica-1594	222	16	of	of	ADP
ecletica-1594	222	17	p	p	NOUN
ecletica-1594	222	18	-	-	PUNCT
ecletica-1594	222	19	glycoprotein	glycoprotein	NOUN
ecletica-1594	222	20	ligand	ligand	NOUN
ecletica-1594	222	21	binding	binding	NOUN
ecletica-1594	222	22	and	and	CCONJ
ecletica-1594	222	23	validation	validation	NOUN
ecletica-1594	222	24	with	with	ADP
ecletica-1594	222	25	efflux	efflux	NOUN
ecletica-1594	222	26	substrate	substrate	NOUN
ecletica-1594	222	27	matched	match	VERB
ecletica-1594	222	28	pairs	pair	NOUN
ecletica-1594	222	29	.	.	PUNCT
ecletica-1594	223	1	journal	journal	NOUN
ecletica-1594	223	2	of	of	ADP
ecletica-1594	223	3	medicinal	medicinal	ADJ
ecletica-1594	223	4	chemistry	chemistry	NOUN
ecletica-1594	223	5	.	.	PUNCT
ecletica-1594	224	1	2024	2024	NUM
ecletica-1594	224	2	,	,	PUNCT
ecletica-1594	224	3	67	67	NUM
ecletica-1594	224	4	(	(	PUNCT
ecletica-1594	224	5	7	7	NUM
ecletica-1594	224	6	)	)	PUNCT
ecletica-1594	224	7	,	,	PUNCT
ecletica-1594	224	8	5854–5865	5854–5865	NUM
ecletica-1594	224	9	.	.	PUNCT
ecletica-1594	225	1	https://doi.org/10.1021/acs.jmedchem.4c00139	https://doi.org/10.1021/acs.jmedchem.4c00139	PROPN
ecletica-1594	225	2	daina	daina	PROPN
ecletica-1594	225	3	,	,	PUNCT
ecletica-1594	225	4	a.	a.	PROPN
ecletica-1594	225	5	;	;	PUNCT
ecletica-1594	225	6	zoete	zoete	NOUN
ecletica-1594	225	7	,	,	PUNCT
ecletica-1594	225	8	v.	v.	CCONJ
ecletica-1594	225	9	aboiled	aboile	VERB
ecletica-1594	225	10	-	-	PUNCT
ecletica-1594	225	11	egg	egg	NOUN
ecletica-1594	225	12	to	to	PART
ecletica-1594	225	13	predict	predict	VERB
ecletica-1594	225	14	gastrointestinal	gastrointestinal	ADJ
ecletica-1594	225	15	absorption	absorption	NOUN
ecletica-1594	225	16	and	and	CCONJ
ecletica-1594	225	17	brain	brain	NOUN
ecletica-1594	225	18	penetration	penetration	NOUN
ecletica-1594	225	19	of	of	ADP
ecletica-1594	225	20	small	small	ADJ
ecletica-1594	225	21	molecules	molecule	NOUN
ecletica-1594	225	22	.	.	PUNCT
ecletica-1594	226	1	chem	chem	NOUN
ecletica-1594	226	2	.	.	PUNCT
ecletica-1594	227	1	med	med	PROPN
ecletica-1594	227	2	.	.	PUNCT
ecletica-1594	227	3	chem	chem	PROPN
ecletica-1594	227	4	.	.	PUNCT
ecletica-1594	228	1	2016	2016	NUM
ecletica-1594	228	2	,	,	PUNCT
ecletica-1594	228	3	11	11	NUM
ecletica-1594	228	4	(	(	PUNCT
ecletica-1594	228	5	11	11	NUM
ecletica-1594	228	6	)	)	PUNCT
ecletica-1594	228	7	,	,	PUNCT
ecletica-1594	228	8	1117–1221	1117–1221	NUM
ecletica-1594	228	9	.	.	PUNCT
ecletica-1594	229	1	https://doi.org/10.1002/cmdc.201600182	https://doi.org/10.1002/cmdc.201600182	NOUN
ecletica-1594	229	2	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	X
ecletica-1594	229	3	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	X
ecletica-1594	230	1	https://doi.org/10.1016/j.imu.2021.100617	https://doi.org/10.1016/j.imu.2021.100617	PROPN
ecletica-1594	230	2	https://doi.org/10.1007/s13337-021-00682-7	https://doi.org/10.1007/s13337-021-00682-7	NUM
ecletica-1594	231	1	https://doi.org/10.2478/auoc-2022-0004	https://doi.org/10.2478/auoc-2022-0004	PROPN
ecletica-1594	231	2	https://doi.org/10.1038/s41598-024-75078-w	https://doi.org/10.1038/s41598-024-75078-w	PROPN
ecletica-1594	231	3	https://doi.org/10.1002/ardp.202000291	https://doi.org/10.1002/ardp.202000291	PROPN
ecletica-1594	231	4	https://doi.org/10.1002/jhet.3933	https://doi.org/10.1002/jhet.3933	NOUN
ecletica-1594	231	5	https://doi.org/10.1063/1.464913	https://doi.org/10.1063/1.464913	PROPN
ecletica-1594	231	6	https://doi.org/10.1021/acs.jmedchem.4c00139	https://doi.org/10.1021/acs.jmedchem.4c00139	ADJ
ecletica-1594	231	7	https://doi.org/10.1002/cmdc.201600182	https://doi.org/10.1002/cmdc.201600182	NOUN
ecletica-1594	231	8	original	original	ADJ
ecletica-1594	231	9	article	article	NOUN
ecletica-1594	231	10	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	X
ecletica-1594	231	11	issn	issn	VERB
ecletica-1594	231	12	1678	1678	NUM
ecletica-1594	231	13	-	-	SYM
ecletica-1594	231	14	4618	4618	NUM
ecletica-1594	231	15	page	page	NOUN
ecletica-1594	231	16	14/14	14/14	NUM
ecletica-1594	231	17	daina	daina	PROPN
ecletica-1594	231	18	,	,	PUNCT
ecletica-1594	231	19	a.	a.	NOUN
ecletica-1594	231	20	;	;	PUNCT
ecletica-1594	231	21	michielin	michielin	PROPN
ecletica-1594	231	22	,	,	PUNCT
ecletica-1594	231	23	o.	o.	PROPN
ecletica-1594	231	24	;	;	PUNCT
ecletica-1594	231	25	zoete	zoete	NOUN
ecletica-1594	231	26	,	,	PUNCT
ecletica-1594	231	27	v.	v.	ADP
ecletica-1594	231	28	swissadme	swissadme	PROPN
ecletica-1594	231	29	:	:	PUNCT
ecletica-1594	231	30	a	a	DET
ecletica-1594	231	31	free	free	ADJ
ecletica-1594	231	32	web	web	NOUN
ecletica-1594	231	33	tool	tool	NOUN
ecletica-1594	231	34	to	to	PART
ecletica-1594	231	35	evaluate	evaluate	VERB
ecletica-1594	231	36	pharmacokinetics	pharmacokinetic	NOUN
ecletica-1594	231	37	,	,	PUNCT
ecletica-1594	231	38	drug	drug	NOUN
ecletica-1594	231	39	likeness	likeness	NOUN
ecletica-1594	231	40	and	and	CCONJ
ecletica-1594	231	41	medicinal	medicinal	ADJ
ecletica-1594	231	42	chemistry	chemistry	NOUN
ecletica-1594	231	43	friendliness	friendliness	NOUN
ecletica-1594	231	44	of	of	ADP
ecletica-1594	231	45	small	small	ADJ
ecletica-1594	231	46	molecules	molecule	NOUN
ecletica-1594	231	47	.	.	PUNCT
ecletica-1594	232	1	scientific	scientific	ADJ
ecletica-1594	232	2	reports	report	NOUN
ecletica-1594	232	3	.	.	PUNCT
ecletica-1594	233	1	2017	2017	NUM
ecletica-1594	233	2	,	,	PUNCT
ecletica-1594	233	3	7	7	NUM
ecletica-1594	233	4	,	,	PUNCT
ecletica-1594	233	5	1−13	1−13	PROPN
ecletica-1594	233	6	.	.	PUNCT
ecletica-1594	234	1	https://doi.org/10.1038/srep42717	https://doi.org/10.1038/srep42717	PROPN
ecletica-1594	234	2	darvas	darvas	PROPN
ecletica-1594	234	3	,	,	PUNCT
ecletica-1594	234	4	f.	f.	PROPN
ecletica-1594	234	5	;	;	PUNCT
ecletica-1594	234	6	keseru	keseru	PROPN
ecletica-1594	234	7	,	,	PUNCT
ecletica-1594	234	8	g.	g.	PROPN
ecletica-1594	234	9	;	;	PUNCT
ecletica-1594	234	10	papp	papp	PROPN
ecletica-1594	234	11	,	,	PUNCT
ecletica-1594	234	12	a.	a.	NOUN
ecletica-1594	234	13	;	;	PUNCT
ecletica-1594	234	14	dorma´n	dorma´n	PROPN
ecletica-1594	234	15	,	,	PUNCT
ecletica-1594	234	16	g.	g.	PROPN
ecletica-1594	234	17	;	;	PUNCT
ecletica-1594	234	18	urge	urge	NOUN
ecletica-1594	234	19	,	,	PUNCT
ecletica-1594	234	20	l.	l.	PROPN
ecletica-1594	234	21	;	;	PUNCT
ecletica-1594	234	22	krajcsi	krajcsi	PROPN
ecletica-1594	234	23	,	,	PUNCT
ecletica-1594	235	1	p.	p.	NOUN
ecletica-1594	235	2	in	in	ADP
ecletica-1594	235	3	silico	silico	NOUN
ecletica-1594	235	4	and	and	CCONJ
ecletica-1594	235	5	ex	ex	PRON
ecletica-1594	235	6	silico	silico	NOUN
ecletica-1594	235	7	adme	adme	NOUN
ecletica-1594	235	8	approaches	approach	VERB
ecletica-1594	235	9	for	for	ADP
ecletica-1594	235	10	drug	drug	NOUN
ecletica-1594	235	11	discovery	discovery	NOUN
ecletica-1594	235	12	.	.	PUNCT
ecletica-1594	236	1	topics	topic	NOUN
ecletica-1594	236	2	in	in	ADP
ecletica-1594	236	3	medicinal	medicinal	ADJ
ecletica-1594	236	4	chemistry	chemistry	NOUN
ecletica-1594	236	5	.	.	PUNCT
ecletica-1594	237	1	2002	2002	NUM
ecletica-1594	237	2	,	,	PUNCT
ecletica-1594	237	3	2	2	NUM
ecletica-1594	237	4	,	,	PUNCT
ecletica-1594	237	5	1287–1304	1287–1304	NUM
ecletica-1594	237	6	.	.	PUNCT
ecletica-1594	238	1	https://doi.org/10.2174/1568026023392841	https://doi.org/10.2174/1568026023392841	PROPN
ecletica-1594	238	2	farhan	farhan	PROPN
ecletica-1594	238	3	,	,	PUNCT
ecletica-1594	238	4	a.	a.	PROPN
ecletica-1594	238	5	k.	k.	PROPN
ecletica-1594	238	6	;	;	PUNCT
ecletica-1594	239	1	sidra	sidra	PROPN
ecletica-1594	239	2	,	,	PUNCT
ecletica-1594	239	3	m.	m.	NOUN
ecletica-1594	239	4	;	;	PUNCT
ecletica-1594	239	5	sadia	sadia	PROPN
ecletica-1594	239	6	,	,	PUNCT
ecletica-1594	239	7	n.	n.	PROPN
ecletica-1594	239	8	;	;	PUNCT
ecletica-1594	239	9	umar	umar	PROPN
ecletica-1594	239	10	,	,	PUNCT
ecletica-1594	239	11	f.	f.	PROPN
ecletica-1594	239	12	;	;	PUNCT
ecletica-1594	239	13	asma	asma	PROPN
ecletica-1594	239	14	,	,	PUNCT
ecletica-1594	239	15	z.	z.	PROPN
ecletica-1594	239	16	;	;	PUNCT
ecletica-1594	239	17	syed	syed	PROPN
ecletica-1594	239	18	majid	majid	PROPN
ecletica-1594	239	19	,	,	PUNCT
ecletica-1594	239	20	b.	b.	PROPN
ecletica-1594	239	21	;	;	PUNCT
ecletica-1594	239	22	abdur	abdur	PROPN
ecletica-1594	239	23	,	,	PUNCT
ecletica-1594	239	24	r.	r.	PROPN
ecletica-1594	239	25	;	;	PUNCT
ecletica-1594	239	26	mohammad	mohammad	PROPN
ecletica-1594	239	27	,	,	PUNCT
ecletica-1594	239	28	s.	s.	PROPN
ecletica-1594	239	29	m.	m.	NOUN
ecletica-1594	239	30	sulfonamides	sulfonamide	NOUN
ecletica-1594	239	31	as	as	ADP
ecletica-1594	239	32	potential	potential	ADJ
ecletica-1594	239	33	bioactive	bioactive	NOUN
ecletica-1594	239	34	scaffolds	scaffold	NOUN
ecletica-1594	239	35	.	.	PUNCT
ecletica-1594	240	1	curr	curr	PROPN
ecletica-1594	240	2	.	.	PUNCT
ecletica-1594	240	3	org	org	PROPN
ecletica-1594	240	4	.	.	PUNCT
ecletica-1594	241	1	chem	chem	PROPN
ecletica-1594	241	2	.	.	PUNCT
ecletica-1594	242	1	2018	2018	NUM
ecletica-1594	242	2	,	,	PUNCT
ecletica-1594	242	3	22	22	NUM
ecletica-1594	242	4	,	,	PUNCT
ecletica-1594	242	5	818−830	818−830	PROPN
ecletica-1594	242	6	.	.	PUNCT
ecletica-1594	242	7	https://doi.org/10.2174/1385272822666180122153839	https://doi.org/10.2174/1385272822666180122153839	PROPN
ecletica-1594	242	8	flores	flores	PROPN
ecletica-1594	242	9	-	-	PUNCT
ecletica-1594	242	10	holguín	holguín	PROPN
ecletica-1594	242	11	,	,	PUNCT
ecletica-1594	242	12	n.	n.	NOUN
ecletica-1594	242	13	;	;	PUNCT
ecletica-1594	242	14	frau	frau	PROPN
ecletica-1594	242	15	,	,	PUNCT
ecletica-1594	242	16	j.	j.	PROPN
ecletica-1594	242	17	;	;	PUNCT
ecletica-1594	242	18	glossman	glossman	NOUN
ecletica-1594	242	19	-	-	PUNCT
ecletica-1594	242	20	mitnik	mitnik	NOUN
ecletica-1594	242	21	,	,	PUNCT
ecletica-1594	242	22	d.	d.	PROPN
ecletica-1594	242	23	calculation	calculation	NOUN
ecletica-1594	242	24	of	of	ADP
ecletica-1594	242	25	the	the	DET
ecletica-1594	242	26	global	global	ADJ
ecletica-1594	242	27	and	and	CCONJ
ecletica-1594	242	28	local	local	ADJ
ecletica-1594	242	29	conceptual	conceptual	ADJ
ecletica-1594	242	30	dft	dft	PROPN
ecletica-1594	242	31	indices	index	NOUN
ecletica-1594	242	32	for	for	ADP
ecletica-1594	242	33	the	the	DET
ecletica-1594	242	34	prediction	prediction	NOUN
ecletica-1594	242	35	of	of	ADP
ecletica-1594	242	36	the	the	DET
ecletica-1594	242	37	chemical	chemical	NOUN
ecletica-1594	242	38	reactivity	reactivity	NOUN
ecletica-1594	242	39	properties	property	NOUN
ecletica-1594	242	40	of	of	ADP
ecletica-1594	242	41	papuamides	papuamide	NOUN
ecletica-1594	242	42	a	a	DET
ecletica-1594	242	43	-	-	PUNCT
ecletica-1594	242	44	f	f	NOUN
ecletica-1594	242	45	marine	marine	ADJ
ecletica-1594	242	46	drugs	drug	NOUN
ecletica-1594	242	47	.	.	PUNCT
ecletica-1594	243	1	molecules	molecule	NOUN
ecletica-1594	243	2	.	.	PUNCT
ecletica-1594	244	1	2019	2019	NUM
ecletica-1594	244	2	,	,	PUNCT
ecletica-1594	244	3	24	24	NUM
ecletica-1594	244	4	(	(	PUNCT
ecletica-1594	244	5	18	18	NUM
ecletica-1594	244	6	)	)	PUNCT
ecletica-1594	244	7	,	,	PUNCT
ecletica-1594	244	8	3312	3312	NUM
ecletica-1594	244	9	.	.	PUNCT
ecletica-1594	245	1	https://doi.org/10.3390/molecules24183312	https://doi.org/10.3390/molecules24183312	PROPN
ecletica-1594	245	2	forgacs	forgac	NOUN
ecletica-1594	245	3	,	,	PUNCT
ecletica-1594	245	4	p.	p.	NOUN
ecletica-1594	245	5	;	;	PUNCT
ecletica-1594	245	6	wengenack	wengenack	NOUN
ecletica-1594	245	7	,	,	PUNCT
ecletica-1594	245	8	n.	n.	PROPN
ecletica-1594	245	9	l.	l.	PROPN
ecletica-1594	245	10	;	;	PUNCT
ecletica-1594	245	11	hall	hall	PROPN
ecletica-1594	245	12	,	,	PUNCT
ecletica-1594	245	13	l.	l.	PROPN
ecletica-1594	245	14	;	;	PUNCT
ecletica-1594	245	15	zimmerman	zimmerman	PROPN
ecletica-1594	245	16	,	,	PUNCT
ecletica-1594	245	17	s.	s.	PROPN
ecletica-1594	245	18	k.	k.	PROPN
ecletica-1594	245	19	;	;	PUNCT
ecletica-1594	245	20	silverman	silverman	PROPN
ecletica-1594	245	21	,	,	PUNCT
ecletica-1594	245	22	m.	m.	PROPN
ecletica-1594	245	23	l.	l.	PROPN
ecletica-1594	245	24	;	;	PUNCT
ecletica-1594	245	25	roberts	roberts	PROPN
ecletica-1594	245	26	,	,	PUNCT
ecletica-1594	245	27	g.	g.	PROPN
ecletica-1594	245	28	d.	d.	PROPN
ecletica-1594	245	29	tuberculosis	tuberculosis	PROPN
ecletica-1594	245	30	and	and	CCONJ
ecletica-1594	245	31	trimethoprim	trimethoprim	ADJ
ecletica-1594	245	32	-	-	PUNCT
ecletica-1594	245	33	sulfamethoxazole	sulfamethoxazole	NOUN
ecletica-1594	245	34	.	.	PUNCT
ecletica-1594	246	1	antimicrobial	antimicrobial	ADJ
ecletica-1594	246	2	agents	agents	PROPN
ecletica-1594	246	3	chemotherapy	chemotherapy	NOUN
ecletica-1594	246	4	.	.	PUNCT
ecletica-1594	247	1	2009	2009	NUM
ecletica-1594	247	2	,	,	PUNCT
ecletica-1594	247	3	53	53	NUM
ecletica-1594	247	4	,	,	PUNCT
ecletica-1594	247	5	4789–4793	4789–4793	NUM
ecletica-1594	247	6	.	.	PUNCT
ecletica-1594	248	1	https://doi.org/10.1128/aac.01658-08	https://doi.org/10.1128/aac.01658-08	PROPN
ecletica-1594	248	2	hu	hu	PROPN
ecletica-1594	248	3	,	,	PUNCT
ecletica-1594	248	4	l.	l.	PROPN
ecletica-1594	248	5	;	;	PUNCT
ecletica-1594	248	6	li	li	PROPN
ecletica-1594	248	7	,	,	PUNCT
ecletica-1594	248	8	z.-r	z.-r	PROPN
ecletica-1594	248	9	.	.	PUNCT
ecletica-1594	248	10	;	;	PUNCT
ecletica-1594	248	11	jiang	jiang	PROPN
ecletica-1594	248	12	,	,	PUNCT
ecletica-1594	248	13	j.-d	j.-d	PROPN
ecletica-1594	248	14	.	.	PUNCT
ecletica-1594	248	15	;	;	PUNCT
ecletica-1594	248	16	boykin	boykin	PROPN
ecletica-1594	248	17	,	,	PUNCT
ecletica-1594	248	18	d.	d.	PROPN
ecletica-1594	248	19	w.	w.	PROPN
ecletica-1594	248	20	novel	novel	PROPN
ecletica-1594	248	21	diaryl	diaryl	NOUN
ecletica-1594	248	22	or	or	CCONJ
ecletica-1594	248	23	heterocyclic	heterocyclic	NOUN
ecletica-1594	248	24	sulfonamides	sulfonamide	NOUN
ecletica-1594	248	25	as	as	ADP
ecletica-1594	248	26	antimitotic	antimitotic	ADJ
ecletica-1594	248	27	agents	agent	NOUN
ecletica-1594	248	28	.	.	PUNCT
ecletica-1594	249	1	anti	anti	ADJ
ecletica-1594	249	2	-	-	ADJ
ecletica-1594	249	3	cancer	cancer	ADJ
ecletica-1594	249	4	agents	agent	NOUN
ecletica-1594	249	5	med	me	VERB
ecletica-1594	249	6	.	.	PUNCT
ecletica-1594	249	7	chem	chem	PROPN
ecletica-1594	249	8	.	.	PUNCT
ecletica-1594	250	1	2008	2008	NUM
ecletica-1594	250	2	,	,	PUNCT
ecletica-1594	250	3	8	8	NUM
ecletica-1594	250	4	(	(	PUNCT
ecletica-1594	250	5	7	7	NUM
ecletica-1594	250	6	)	)	PUNCT
ecletica-1594	250	7	,	,	PUNCT
ecletica-1594	251	1	739−745	739−745	PROPN
ecletica-1594	251	2	.	.	PUNCT
ecletica-1594	251	3	https://doi.org/10.2174/187152008785914806	https://doi.org/10.2174/187152008785914806	NOUN
ecletica-1594	251	4	krátký	krátký	PROPN
ecletica-1594	251	5	,	,	PUNCT
ecletica-1594	251	6	m.	m.	NOUN
ecletica-1594	251	7	;	;	PUNCT
ecletica-1594	251	8	vinsová	vinsová	PROPN
ecletica-1594	251	9	,	,	PUNCT
ecletica-1594	251	10	j.	j.	PROPN
ecletica-1594	251	11	;	;	PUNCT
ecletica-1594	251	12	volková	volková	ADV
ecletica-1594	251	13	,	,	PUNCT
ecletica-1594	251	14	m.	m.	NOUN
ecletica-1594	251	15	;	;	PUNCT
ecletica-1594	251	16	buchta	buchta	NOUN
ecletica-1594	251	17	,	,	PUNCT
ecletica-1594	251	18	v.	v.	ADV
ecletica-1594	251	19	;	;	PUNCT
ecletica-1594	251	20	trejtnar	trejtnar	PROPN
ecletica-1594	251	21	,	,	PUNCT
ecletica-1594	251	22	f.	f.	PROPN
ecletica-1594	251	23	;	;	PUNCT
ecletica-1594	251	24	stolaríková	stolaríková	PROPN
ecletica-1594	251	25	,	,	PUNCT
ecletica-1594	251	26	j.	j.	PROPN
ecletica-1594	251	27	antimicrobial	antimicrobial	ADJ
ecletica-1594	251	28	activity	activity	NOUN
ecletica-1594	251	29	of	of	ADP
ecletica-1594	251	30	sulfonamides	sulfonamide	NOUN
ecletica-1594	251	31	containing	contain	VERB
ecletica-1594	251	32	5	5	NUM
ecletica-1594	251	33	-	-	PUNCT
ecletica-1594	251	34	chloro2	chloro2	NOUN
ecletica-1594	251	35	-	-	PUNCT
ecletica-1594	251	36	hydroxybenzaldehyde	hydroxybenzaldehyde	NOUN
ecletica-1594	251	37	and	and	CCONJ
ecletica-1594	251	38	5	5	NUM
ecletica-1594	251	39	-	-	PUNCT
ecletica-1594	251	40	chloro-2	chloro-2	VERB
ecletica-1594	251	41	-	-	PUNCT
ecletica-1594	251	42	hydroxybenzoic	hydroxybenzoic	NOUN
ecletica-1594	251	43	acid	acid	NOUN
ecletica-1594	251	44	scaffold	scaffold	NOUN
ecletica-1594	251	45	.	.	PUNCT
ecletica-1594	252	1	european	european	ADJ
ecletica-1594	252	2	journal	journal	PROPN
ecletica-1594	252	3	of	of	ADP
ecletica-1594	252	4	medicinal	medicinal	ADJ
ecletica-1594	252	5	chemistry	chemistry	NOUN
ecletica-1594	252	6	.	.	PUNCT
ecletica-1594	253	1	2012	2012	NUM
ecletica-1594	253	2	,	,	PUNCT
ecletica-1594	253	3	50	50	NUM
ecletica-1594	253	4	,	,	PUNCT
ecletica-1594	253	5	433–440	433–440	NUM
ecletica-1594	253	6	.	.	PUNCT
ecletica-1594	254	1	https://doi.org/10.1016/j.ejmech.2012.01.060	https://doi.org/10.1016/j.ejmech.2012.01.060	PROPN
ecletica-1594	254	2	lee	lee	PROPN
ecletica-1594	254	3	,	,	PUNCT
ecletica-1594	254	4	c.	c.	PROPN
ecletica-1594	254	5	,	,	PUNCT
ecletica-1594	254	6	yang	yang	PROPN
ecletica-1594	254	7	,	,	PUNCT
ecletica-1594	254	8	w.	w.	PROPN
ecletica-1594	254	9	,	,	PUNCT
ecletica-1594	254	10	and	and	CCONJ
ecletica-1594	254	11	parr	parr	PROPN
ecletica-1594	254	12	,	,	PUNCT
ecletica-1594	254	13	r.	r.	PROPN
ecletica-1594	254	14	g.	g.	PROPN
ecletica-1594	254	15	,	,	PUNCT
ecletica-1594	254	16	development	development	NOUN
ecletica-1594	254	17	of	of	ADP
ecletica-1594	254	18	the	the	DET
ecletica-1594	254	19	colle	colle	NOUN
ecletica-1594	254	20	-	-	PUNCT
ecletica-1594	254	21	salvetti	salvetti	VERB
ecletica-1594	254	22	correlation	correlation	NOUN
ecletica-1594	254	23	-	-	PUNCT
ecletica-1594	254	24	energy	energy	NOUN
ecletica-1594	254	25	formula	formula	NOUN
ecletica-1594	254	26	into	into	ADP
ecletica-1594	254	27	a	a	DET
ecletica-1594	254	28	functional	functional	NOUN
ecletica-1594	254	29	of	of	ADP
ecletica-1594	254	30	the	the	DET
ecletica-1594	254	31	electron	electron	NOUN
ecletica-1594	254	32	density	density	NOUN
ecletica-1594	254	33	.	.	PUNCT
ecletica-1594	255	1	phys	phy	NOUN
ecletica-1594	255	2	.	.	PUNCT
ecletica-1594	256	1	rev	rev	PROPN
ecletica-1594	256	2	.	.	PROPN
ecletica-1594	257	1	b	b	PROPN
ecletica-1594	257	2	1988	1988	NUM
ecletica-1594	257	3	,	,	PUNCT
ecletica-1594	257	4	37	37	NUM
ecletica-1594	257	5	,	,	PUNCT
ecletica-1594	257	6	785	785	NUM
ecletica-1594	257	7	-	-	SYM
ecletica-1594	257	8	789	789	NUM
ecletica-1594	257	9	lipinski	lipinski	PROPN
ecletica-1594	257	10	,	,	PUNCT
ecletica-1594	257	11	c.	c.	PROPN
ecletica-1594	257	12	a.	a.	PROPN
ecletica-1594	257	13	lead	lead	PROPN
ecletica-1594	257	14	-	-	PUNCT
ecletica-1594	257	15	and	and	CCONJ
ecletica-1594	257	16	drug	drug	NOUN
ecletica-1594	257	17	-	-	PUNCT
ecletica-1594	257	18	like	like	ADJ
ecletica-1594	257	19	compounds	compound	NOUN
ecletica-1594	257	20	:	:	PUNCT
ecletica-1594	257	21	the	the	DET
ecletica-1594	257	22	rule	rule	NOUN
ecletica-1594	257	23	-	-	PUNCT
ecletica-1594	257	24	of	of	ADP
ecletica-1594	257	25	-	-	PUNCT
ecletica-1594	257	26	five	five	NUM
ecletica-1594	257	27	revolution	revolution	NOUN
ecletica-1594	257	28	.	.	PUNCT
ecletica-1594	258	1	drug	drug	NOUN
ecletica-1594	258	2	discovery	discovery	PROPN
ecletica-1594	258	3	today	today	NOUN
ecletica-1594	258	4	:	:	PUNCT
ecletica-1594	258	5	technologies	technology	NOUN
ecletica-1594	258	6	.	.	PUNCT
ecletica-1594	259	1	2004	2004	NUM
ecletica-1594	259	2	,	,	PUNCT
ecletica-1594	259	3	1	1	NUM
ecletica-1594	259	4	(	(	PUNCT
ecletica-1594	259	5	4	4	NUM
ecletica-1594	259	6	)	)	PUNCT
ecletica-1594	259	7	,	,	PUNCT
ecletica-1594	259	8	337–341	337–341	NUM
ecletica-1594	259	9	.	.	PUNCT
ecletica-1594	260	1	https://doi.org/10.1016/j.ddtec.2004.11.007	https://doi.org/10.1016/j.ddtec.2004.11.007	VERB
ecletica-1594	260	2	manzanilla	manzanilla	NOUN
ecletica-1594	260	3	,	,	PUNCT
ecletica-1594	260	4	b.	b.	PROPN
ecletica-1594	260	5	;	;	PUNCT
ecletica-1594	260	6	robles	robles	PROPN
ecletica-1594	260	7	,	,	PUNCT
ecletica-1594	260	8	j.	j.	PROPN
ecletica-1594	260	9	conceptual	conceptual	PROPN
ecletica-1594	260	10	dft	dft	PROPN
ecletica-1594	260	11	reactivity	reactivity	NOUN
ecletica-1594	260	12	descriptors	descriptor	VERB
ecletica-1594	260	13	computational	computational	ADJ
ecletica-1594	260	14	study	study	NOUN
ecletica-1594	260	15	of	of	ADP
ecletica-1594	260	16	graphene	graphene	NOUN
ecletica-1594	260	17	and	and	CCONJ
ecletica-1594	260	18	derivatives	derivative	NOUN
ecletica-1594	260	19	flakes	flake	NOUN
ecletica-1594	260	20	:	:	PUNCT
ecletica-1594	260	21	doped	dope	VERB
ecletica-1594	260	22	graphene	graphene	NOUN
ecletica-1594	260	23	,	,	PUNCT
ecletica-1594	260	24	graphane	graphane	NOUN
ecletica-1594	260	25	,	,	PUNCT
ecletica-1594	260	26	fluorographene	fluorographene	NOUN
ecletica-1594	260	27	,	,	PUNCT
ecletica-1594	260	28	graphene	graphene	ADJ
ecletica-1594	260	29	oxide	oxide	NOUN
ecletica-1594	260	30	,	,	PUNCT
ecletica-1594	260	31	graphyne	graphyne	NOUN
ecletica-1594	260	32	,	,	PUNCT
ecletica-1594	260	33	and	and	CCONJ
ecletica-1594	260	34	graphdiyne	graphdiyne	PROPN
ecletica-1594	260	35	.	.	PUNCT
ecletica-1594	261	1	journal	journal	PROPN
ecletica-1594	261	2	of	of	ADP
ecletica-1594	261	3	mexican	mexican	PROPN
ecletica-1594	261	4	chemical	chemical	PROPN
ecletica-1594	261	5	society	society	NOUN
ecletica-1594	261	6	.	.	PUNCT
ecletica-1594	262	1	2020	2020	NUM
ecletica-1594	262	2	,	,	PUNCT
ecletica-1594	262	3	64	64	NUM
ecletica-1594	262	4	(	(	PUNCT
ecletica-1594	262	5	3	3	NUM
ecletica-1594	262	6	)	)	PUNCT
ecletica-1594	262	7	,	,	PUNCT
ecletica-1594	262	8	238–252	238–252	NUM
ecletica-1594	262	9	.	.	PUNCT
ecletica-1594	263	1	https://doi.org/10.29356/jmcs.v64i3.1167	https://doi.org/10.29356/jmcs.v64i3.1167	NUM
ecletica-1594	263	2	masters	master	NOUN
ecletica-1594	263	3	,	,	PUNCT
ecletica-1594	263	4	p.	p.	NOUN
ecletica-1594	263	5	a.	a.	NOUN
ecletica-1594	263	6	;	;	PUNCT
ecletica-1594	263	7	o’bryan	o’bryan	PROPN
ecletica-1594	263	8	,	,	PUNCT
ecletica-1594	263	9	t.	t.	NOUN
ecletica-1594	263	10	a.	a.	NOUN
ecletica-1594	263	11	;	;	PUNCT
ecletica-1594	263	12	zurlo	zurlo	PROPN
ecletica-1594	263	13	,	,	PUNCT
ecletica-1594	263	14	j.	j.	PROPN
ecletica-1594	263	15	;	;	PUNCT
ecletica-1594	263	16	miller	miller	PROPN
ecletica-1594	263	17	,	,	PUNCT
ecletica-1594	263	18	d.	d.	PROPN
ecletica-1594	263	19	q.	q.	PROPN
ecletica-1594	263	20	;	;	PUNCT
ecletica-1594	263	21	joshi	joshi	PROPN
ecletica-1594	263	22	,	,	PUNCT
ecletica-1594	263	23	n.	n.	PROPN
ecletica-1594	263	24	trimethoprim	trimethoprim	ADJ
ecletica-1594	263	25	-	-	PUNCT
ecletica-1594	263	26	sulfamethoxazole	sulfamethoxazole	NOUN
ecletica-1594	263	27	revisited	revisit	VERB
ecletica-1594	263	28	.	.	PUNCT
ecletica-1594	264	1	archives	archive	NOUN
ecletica-1594	264	2	of	of	ADP
ecletica-1594	264	3	internal	internal	ADJ
ecletica-1594	264	4	medicine	medicine	NOUN
ecletica-1594	264	5	.	.	PUNCT
ecletica-1594	265	1	2003	2003	NUM
ecletica-1594	265	2	,	,	PUNCT
ecletica-1594	265	3	163	163	NUM
ecletica-1594	265	4	,	,	PUNCT
ecletica-1594	265	5	402–410	402–410	NUM
ecletica-1594	265	6	.	.	PUNCT
ecletica-1594	266	1	https://doi.org/10.1001/archinte.163.4.402	https://doi.org/10.1001/archinte.163.4.402	NOUN
ecletica-1594	266	2	oyebamiji	oyebamiji	PROPN
ecletica-1594	266	3	,	,	PUNCT
ecletica-1594	266	4	a.	a.	PROPN
ecletica-1594	266	5	k.	k.	PROPN
ecletica-1594	266	6	;	;	PUNCT
ecletica-1594	266	7	fadare	fadare	VERB
ecletica-1594	266	8	,	,	PUNCT
ecletica-1594	266	9	o.	o.	NOUN
ecletica-1594	266	10	a.	a.	NOUN
ecletica-1594	266	11	;	;	PUNCT
ecletica-1594	266	12	akintelu	akintelu	ADV
ecletica-1594	266	13	,	,	PUNCT
ecletica-1594	266	14	s.	s.	PROPN
ecletica-1594	266	15	a.	a.	PROPN
ecletica-1594	266	16	;	;	PUNCT
ecletica-1594	266	17	semire	semire	NOUN
ecletica-1594	266	18	,	,	PUNCT
ecletica-1594	266	19	b.	b.	PROPN
ecletica-1594	266	20	biological	biological	ADJ
ecletica-1594	266	21	studies	study	NOUN
ecletica-1594	266	22	on	on	ADP
ecletica-1594	266	23	anthra[1,9‑cd]pyrazol‑6(2d)‑one	anthra[1,9‑cd]pyrazol‑6(2d)‑one	PROPN
ecletica-1594	266	24	analogues	analogue	NOUN
ecletica-1594	266	25	as	as	ADP
ecletica-1594	266	26	anti‑vascular	anti‑vascular	NUM
ecletica-1594	266	27	endothelial	endothelial	ADJ
ecletica-1594	266	28	growth	growth	NOUN
ecletica-1594	266	29	factor	factor	NOUN
ecletica-1594	266	30	via	via	ADP
ecletica-1594	266	31	in	in	ADP
ecletica-1594	266	32	silico	silico	NOUN
ecletica-1594	266	33	mechanisms	mechanism	NOUN
ecletica-1594	266	34	.	.	PUNCT
ecletica-1594	267	1	chemistry	chemistry	PROPN
ecletica-1594	267	2	africa	africa	PROPN
ecletica-1594	267	3	.	.	PROPN
ecletica-1594	267	4	2021	2021	NUM
ecletica-1594	267	5	,	,	PUNCT
ecletica-1594	267	6	4	4	NUM
ecletica-1594	267	7	,	,	PUNCT
ecletica-1594	267	8	955–963	955–963	NUM
ecletica-1594	267	9	https://doi.org/10.1007/s42250-021-00276-2	https://doi.org/10.1007/s42250-021-00276-2	NUM
ecletica-1594	267	10	oyebamiji	oyebamiji	NOUN
ecletica-1594	267	11	,	,	PUNCT
ecletica-1594	267	12	a.	a.	PROPN
ecletica-1594	267	13	k.	k.	PROPN
ecletica-1594	267	14	;	;	PUNCT
ecletica-1594	267	15	semire	semire	PROPN
ecletica-1594	267	16	b.	b.	PROPN
ecletica-1594	267	17	dft	dft	PROPN
ecletica-1594	267	18	-	-	PUNCT
ecletica-1594	267	19	qsar	qsar	NOUN
ecletica-1594	267	20	model	model	NOUN
ecletica-1594	267	21	and	and	CCONJ
ecletica-1594	267	22	docking	dock	VERB
ecletica-1594	267	23	studies	study	NOUN
ecletica-1594	267	24	of	of	ADP
ecletica-1594	267	25	antiliver	antiliver	NOUN
ecletica-1594	267	26	cancer	cancer	NOUN
ecletica-1594	267	27	(	(	PUNCT
ecletica-1594	267	28	hepg-2	hepg-2	NOUN
ecletica-1594	267	29	)	)	PUNCT
ecletica-1594	267	30	activities	activity	NOUN
ecletica-1594	267	31	of	of	ADP
ecletica-1594	267	32	1	1	NUM
ecletica-1594	267	33	,	,	PUNCT
ecletica-1594	267	34	4	4	NUM
ecletica-1594	267	35	-	-	PUNCT
ecletica-1594	267	36	diydropyridine	diydropyridine	NOUN
ecletica-1594	267	37	based	base	VERB
ecletica-1594	267	38	derivatives	derivative	NOUN
ecletica-1594	267	39	.	.	PUNCT
ecletica-1594	268	1	cancer	cancer	NOUN
ecletica-1594	268	2	biology	biology	NOUN
ecletica-1594	268	3	.	.	PUNCT
ecletica-1594	269	1	2016	2016	NUM
ecletica-1594	269	2	,	,	PUNCT
ecletica-1594	269	3	6	6	NUM
ecletica-1594	269	4	(	(	PUNCT
ecletica-1594	269	5	2	2	NUM
ecletica-1594	269	6	)	)	PUNCT
ecletica-1594	269	7	,	,	PUNCT
ecletica-1594	269	8	69–72	69–72	NUM
ecletica-1594	269	9	.	.	PUNCT
ecletica-1594	270	1	https://doi.org/10.7537/marscbj06021610	https://doi.org/10.7537/marscbj06021610	PROPN
ecletica-1594	270	2	oyeneyin	oyeneyin	PROPN
ecletica-1594	270	3	,	,	PUNCT
ecletica-1594	270	4	o.	o.	PROPN
ecletica-1594	270	5	e.	e.	PROPN
ecletica-1594	270	6	dft	dft	PROPN
ecletica-1594	270	7	and	and	CCONJ
ecletica-1594	270	8	monte	monte	PROPN
ecletica-1594	270	9	carlo	carlo	PROPN
ecletica-1594	270	10	simulations	simulation	NOUN
ecletica-1594	270	11	on	on	ADP
ecletica-1594	270	12	the	the	DET
ecletica-1594	270	13	corrosion	corrosion	NOUN
ecletica-1594	270	14	inhibitive	inhibitive	ADJ
ecletica-1594	270	15	potentials	potential	NOUN
ecletica-1594	270	16	of	of	ADP
ecletica-1594	270	17	some	some	DET
ecletica-1594	270	18	furan	furan	PROPN
ecletica-1594	270	19	-	-	PUNCT
ecletica-1594	270	20	based	base	VERB
ecletica-1594	270	21	carbohydrazide	carbohydrazide	NOUN
ecletica-1594	270	22	derivatives	derivative	NOUN
ecletica-1594	270	23	.	.	PUNCT
ecletica-1594	271	1	letter	letter	NOUN
ecletica-1594	271	2	of	of	ADP
ecletica-1594	271	3	applied	apply	VERB
ecletica-1594	271	4	nanobio	nanobio	NOUN
ecletica-1594	271	5	science	science	NOUN
ecletica-1594	271	6	.	.	PUNCT
ecletica-1594	272	1	2023	2023	NUM
ecletica-1594	272	2	,	,	PUNCT
ecletica-1594	272	3	12	12	NUM
ecletica-1594	272	4	(	(	PUNCT
ecletica-1594	272	5	4	4	NUM
ecletica-1594	272	6	)	)	PUNCT
ecletica-1594	272	7	,	,	PUNCT
ecletica-1594	272	8	1–22	1–22	NOUN
ecletica-1594	272	9	.	.	PUNCT
ecletica-1594	273	1	https://doi.org/10.33263/lianbs124.113	https://doi.org/10.33263/lianbs124.113	PROPN
ecletica-1594	273	2	parr	parr	PROPN
ecletica-1594	273	3	,	,	PUNCT
ecletica-1594	273	4	r.	r.	PROPN
ecletica-1594	273	5	g.	g.	PROPN
ecletica-1594	273	6	;	;	PUNCT
ecletica-1594	273	7	szentpaly	szentpaly	PROPN
ecletica-1594	273	8	,	,	PUNCT
ecletica-1594	273	9	l.	l.	PROPN
ecletica-1594	273	10	;	;	PUNCT
ecletica-1594	273	11	liu	liu	PROPN
ecletica-1594	273	12	,	,	PUNCT
ecletica-1594	273	13	s.	s.	PROPN
ecletica-1594	273	14	electrophilicity	electrophilicity	PROPN
ecletica-1594	273	15	index	index	PROPN
ecletica-1594	273	16	.	.	PUNCT
ecletica-1594	274	1	journal	journal	PROPN
ecletica-1594	274	2	of	of	ADP
ecletica-1594	274	3	american	american	PROPN
ecletica-1594	274	4	chemical	chemical	PROPN
ecletica-1594	274	5	society	society	NOUN
ecletica-1594	274	6	.	.	PUNCT
ecletica-1594	275	1	1999	1999	NUM
ecletica-1594	275	2	,	,	PUNCT
ecletica-1594	275	3	121	121	NUM
ecletica-1594	275	4	(	(	PUNCT
ecletica-1594	275	5	9	9	NUM
ecletica-1594	275	6	)	)	PUNCT
ecletica-1594	275	7	,	,	PUNCT
ecletica-1594	275	8	1922–1924	1922–1924	NUM
ecletica-1594	275	9	.	.	PUNCT
ecletica-1594	276	1	https://doi.org/10.1021/ja983494x	https://doi.org/10.1021/ja983494x	DET
ecletica-1594	276	2	ramírez	ramírez	NOUN
ecletica-1594	276	3	-	-	PUNCT
ecletica-1594	276	4	martínez	martínez	NOUN
ecletica-1594	276	5	,	,	PUNCT
ecletica-1594	276	6	c.	c.	NOUN
ecletica-1594	276	7	;	;	PUNCT
ecletica-1594	276	8	zárate	zárate	NOUN
ecletica-1594	276	9	-	-	PUNCT
ecletica-1594	276	10	hernández	hernández	PROPN
ecletica-1594	276	11	,	,	PUNCT
ecletica-1594	276	12	l.	l.	PROPN
ecletica-1594	276	13	a.	a.	PROPN
ecletica-1594	276	14	;	;	PUNCT
ecletica-1594	276	15	camacho	camacho	PROPN
ecletica-1594	276	16	-	-	PUNCT
ecletica-1594	276	17	mendoza	mendoza	PROPN
ecletica-1594	276	18	,	,	PUNCT
ecletica-1594	276	19	r.	r.	PROPN
ecletica-1594	276	20	l.	l.	PROPN
ecletica-1594	276	21	;	;	PUNCT
ecletica-1594	276	22	gonzález	gonzález	PROPN
ecletica-1594	276	23	-	-	PUNCT
ecletica-1594	276	24	montiel	montiel	PROPN
ecletica-1594	276	25	,	,	PUNCT
ecletica-1594	276	26	s.	s.	PROPN
ecletica-1594	276	27	;	;	PUNCT
ecletica-1594	276	28	meneses	menese	NOUN
ecletica-1594	276	29	-	-	PUNCT
ecletica-1594	276	30	viveros	vivero	NOUN
ecletica-1594	276	31	,	,	PUNCT
ecletica-1594	276	32	a.	a.	NOUN
ecletica-1594	276	33	;	;	PUNCT
ecletica-1594	276	34	cruz	cruz	NOUN
ecletica-1594	276	35	-	-	PUNCT
ecletica-1594	276	36	borbolla	borbolla	PROPN
ecletica-1594	276	37	,	,	PUNCT
ecletica-1594	276	38	j.	j.	PROPN
ecletica-1594	276	39	the	the	DET
ecletica-1594	276	40	use	use	NOUN
ecletica-1594	276	41	of	of	ADP
ecletica-1594	276	42	global	global	ADJ
ecletica-1594	276	43	and	and	CCONJ
ecletica-1594	276	44	local	local	ADJ
ecletica-1594	276	45	reactivity	reactivity	NOUN
ecletica-1594	276	46	descriptors	descriptor	NOUN
ecletica-1594	276	47	of	of	ADP
ecletica-1594	276	48	conceptual	conceptual	ADJ
ecletica-1594	276	49	dft	dft	PROPN
ecletica-1594	276	50	to	to	PART
ecletica-1594	276	51	describe	describe	VERB
ecletica-1594	276	52	toxicity	toxicity	NOUN
ecletica-1594	276	53	of	of	ADP
ecletica-1594	276	54	benzoic	benzoic	ADJ
ecletica-1594	276	55	acid	acid	NOUN
ecletica-1594	276	56	derivatives	derivative	NOUN
ecletica-1594	276	57	.	.	PUNCT
ecletica-1594	277	1	computational	computational	ADJ
ecletica-1594	277	2	and	and	CCONJ
ecletica-1594	277	3	theoretical	theoretical	ADJ
ecletica-1594	277	4	chemistry	chemistry	NOUN
ecletica-1594	277	5	.	.	PUNCT
ecletica-1594	278	1	2023	2023	NUM
ecletica-1594	278	2	,	,	PUNCT
ecletica-1594	278	3	1226	1226	NUM
ecletica-1594	278	4	,	,	PUNCT
ecletica-1594	278	5	114211	114211	NUM
ecletica-1594	278	6	.	.	PUNCT
ecletica-1594	279	1	https://doi.org/10.1016/j.comptc.2023.114211	https://doi.org/10.1016/j.comptc.2023.114211	PROPN
ecletica-1594	279	2	rasigade	rasigade	VERB
ecletica-1594	279	3	,	,	PUNCT
ecletica-1594	279	4	j.	j.	PROPN
ecletica-1594	279	5	p.	p.	PROPN
ecletica-1594	279	6	;	;	PUNCT
ecletica-1594	279	7	vandenesch	vandenesch	PROPN
ecletica-1594	279	8	,	,	PUNCT
ecletica-1594	279	9	f.	f.	PROPN
ecletica-1594	279	10	staphylococcus	staphylococcus	PROPN
ecletica-1594	279	11	aureus	aureus	PROPN
ecletica-1594	279	12	:	:	PUNCT
ecletica-1594	279	13	a	a	DET
ecletica-1594	279	14	pathogen	pathogen	NOUN
ecletica-1594	279	15	with	with	ADP
ecletica-1594	279	16	still	still	ADV
ecletica-1594	279	17	unresolved	unresolved	ADJ
ecletica-1594	279	18	issues	issue	NOUN
ecletica-1594	279	19	.	.	PUNCT
ecletica-1594	280	1	infect	infect	VERB
ecletica-1594	280	2	.	.	PUNCT
ecletica-1594	281	1	genet	genet	NOUN
ecletica-1594	281	2	.	.	PUNCT
ecletica-1594	282	1	evol	evol	NOUN
ecletica-1594	282	2	.	.	PUNCT
ecletica-1594	283	1	2014	2014	NUM
ecletica-1594	283	2	,	,	PUNCT
ecletica-1594	283	3	21	21	NUM
ecletica-1594	283	4	,	,	PUNCT
ecletica-1594	283	5	510–514	510–514	NUM
ecletica-1594	283	6	.	.	PUNCT
ecletica-1594	284	1	https://doi.org/10.1016/j.meegid.2013.08.018	https://doi.org/10.1016/j.meegid.2013.08.018	NOUN
ecletica-1594	284	2	ratchanok	ratchanok	NOUN
ecletica-1594	284	3	,	,	PUNCT
ecletica-1594	284	4	p.	p.	NOUN
ecletica-1594	284	5	;	;	PUNCT
ecletica-1594	284	6	prasit	prasit	NOUN
ecletica-1594	284	7	,	,	PUNCT
ecletica-1594	284	8	m.	m.	NOUN
ecletica-1594	284	9	;	;	PUNCT
ecletica-1594	284	10	veda	veda	PROPN
ecletica-1594	284	11	,	,	PUNCT
ecletica-1594	284	12	p.	p.	PROPN
ecletica-1594	284	13	;	;	PUNCT
ecletica-1594	284	14	anusit	anusit	PROPN
ecletica-1594	284	15	,	,	PUNCT
ecletica-1594	284	16	t.	t.	PROPN
ecletica-1594	284	17	;	;	PUNCT
ecletica-1594	284	18	supaluk	supaluk	PROPN
ecletica-1594	284	19	,	,	PUNCT
ecletica-1594	284	20	p.	p.	NOUN
ecletica-1594	284	21	;	;	PUNCT
ecletica-1594	284	22	somsak	somsak	PROPN
ecletica-1594	284	23	,	,	PUNCT
ecletica-1594	284	24	r.	r.	PROPN
ecletica-1594	284	25	;	;	PUNCT
ecletica-1594	284	26	virapong	virapong	NOUN
ecletica-1594	284	27	,	,	PUNCT
ecletica-1594	284	28	p.	p.	NOUN
ecletica-1594	284	29	investigations	investigation	NOUN
ecletica-1594	284	30	on	on	ADP
ecletica-1594	284	31	anticancer	anticancer	NOUN
ecletica-1594	284	32	and	and	CCONJ
ecletica-1594	284	33	antimalarial	antimalarial	ADJ
ecletica-1594	284	34	activities	activity	NOUN
ecletica-1594	284	35	of	of	ADP
ecletica-1594	284	36	indole	indole	ADJ
ecletica-1594	284	37	sulfonamide	sulfonamide	NOUN
ecletica-1594	284	38	derivatives	derivative	NOUN
ecletica-1594	284	39	and	and	CCONJ
ecletica-1594	284	40	in	in	ADP
ecletica-1594	284	41	silico	silico	NOUN
ecletica-1594	284	42	studies	study	NOUN
ecletica-1594	284	43	.	.	PUNCT
ecletica-1594	285	1	acs	acs	PROPN
ecletica-1594	285	2	omega	omega	NOUN
ecletica-1594	285	3	.	.	PUNCT
ecletica-1594	286	1	2021	2021	NUM
ecletica-1594	286	2	,	,	PUNCT
ecletica-1594	286	3	6	6	NUM
ecletica-1594	286	4	,	,	PUNCT
ecletica-1594	286	5	31854−31868	31854−31868	NUM
ecletica-1594	286	6	.	.	PUNCT
ecletica-1594	287	1	https://doi.org/10.1021/acsomega.1c04552	https://doi.org/10.1021/acsomega.1c04552	PROPN
ecletica-1594	287	2	sun	sun	PROPN
ecletica-1594	287	3	,	,	PUNCT
ecletica-1594	287	4	d.	d.	PROPN
ecletica-1594	287	5	;	;	PUNCT
ecletica-1594	287	6	gao	gao	PROPN
ecletica-1594	287	7	,	,	PUNCT
ecletica-1594	287	8	w.	w.	PROPN
ecletica-1594	287	9	;	;	PUNCT
ecletica-1594	287	10	hu	hu	PROPN
ecletica-1594	287	11	,	,	PUNCT
ecletica-1594	287	12	h.	h.	PROPN
ecletica-1594	287	13	;	;	PUNCT
ecletica-1594	287	14	zhou	zhou	PROPN
ecletica-1594	287	15	,	,	PUNCT
ecletica-1594	287	16	s.	s.	PROPN
ecletica-1594	287	17	why	why	SCONJ
ecletica-1594	287	18	90	90	NUM
ecletica-1594	287	19	%	%	NOUN
ecletica-1594	287	20	of	of	ADP
ecletica-1594	287	21	clinical	clinical	ADJ
ecletica-1594	287	22	drug	drug	NOUN
ecletica-1594	287	23	development	development	NOUN
ecletica-1594	287	24	fails	fail	VERB
ecletica-1594	287	25	and	and	CCONJ
ecletica-1594	287	26	how	how	SCONJ
ecletica-1594	287	27	to	to	PART
ecletica-1594	287	28	improve	improve	VERB
ecletica-1594	287	29	it	it	PRON
ecletica-1594	287	30	?	?	PUNCT
ecletica-1594	288	1	acta	acta	PROPN
ecletica-1594	288	2	pharmaceutica	pharmaceutica	PROPN
ecletica-1594	288	3	sinica	sinica	PROPN
ecletica-1594	288	4	b.	b.	PROPN
ecletica-1594	288	5	2022	2022	NUM
ecletica-1594	288	6	,	,	PUNCT
ecletica-1594	288	7	12	12	NUM
ecletica-1594	288	8	(	(	PUNCT
ecletica-1594	288	9	7	7	NUM
ecletica-1594	288	10	)	)	PUNCT
ecletica-1594	288	11	,	,	PUNCT
ecletica-1594	288	12	3049	3049	NUM
ecletica-1594	288	13	–	–	PUNCT
ecletica-1594	288	14	3062	3062	NUM
ecletica-1594	288	15	.	.	PUNCT
ecletica-1594	289	1	https://doi.org/10.1016/j.apsb.2022.02.002	https://doi.org/10.1016/j.apsb.2022.02.002	NOUN
ecletica-1594	289	2	supuran	supuran	NOUN
ecletica-1594	289	3	,	,	PUNCT
ecletica-1594	289	4	c.	c.	PROPN
ecletica-1594	289	5	t.	t.	PROPN
ecletica-1594	289	6	special	special	ADJ
ecletica-1594	289	7	issue	issue	NOUN
ecletica-1594	289	8	:	:	PUNCT
ecletica-1594	289	9	sulfonamides	sulfonamide	NOUN
ecletica-1594	289	10	.	.	PUNCT
ecletica-1594	290	1	molecules	molecule	NOUN
ecletica-1594	290	2	.	.	PUNCT
ecletica-1594	291	1	2017	2017	NUM
ecletica-1594	291	2	,	,	PUNCT
ecletica-1594	291	3	22	22	NUM
ecletica-1594	291	4	(	(	PUNCT
ecletica-1594	291	5	10	10	NUM
ecletica-1594	291	6	)	)	PUNCT
ecletica-1594	291	7	,	,	PUNCT
ecletica-1594	291	8	1642	1642	NUM
ecletica-1594	291	9	.	.	PUNCT
ecletica-1594	292	1	https://doi.org/10.3390/molecules22101642	https://doi.org/10.3390/molecules22101642	ADJ
ecletica-1594	292	2	thanikaivelan	thanikaivelan	NOUN
ecletica-1594	292	3	,	,	PUNCT
ecletica-1594	292	4	p.	p.	NOUN
ecletica-1594	292	5	,	,	PUNCT
ecletica-1594	292	6	subramanian	subramanian	PROPN
ecletica-1594	292	7	,	,	PUNCT
ecletica-1594	292	8	v.	v.	PROPN
ecletica-1594	292	9	;	;	PUNCT
ecletica-1594	292	10	rao	rao	PROPN
ecletica-1594	292	11	,	,	PUNCT
ecletica-1594	292	12	j.	j.	PROPN
ecletica-1594	292	13	r.	r.	PROPN
ecletica-1594	292	14	;	;	PUNCT
ecletica-1594	292	15	nair	nair	PROPN
ecletica-1594	292	16	,	,	PUNCT
ecletica-1594	292	17	b.	b.	PROPN
ecletica-1594	292	18	u.	u.	PROPN
ecletica-1594	292	19	application	application	NOUN
ecletica-1594	292	20	of	of	ADP
ecletica-1594	292	21	quantum	quantum	ADJ
ecletica-1594	292	22	chemical	chemical	NOUN
ecletica-1594	292	23	descriptor	descriptor	NOUN
ecletica-1594	292	24	in	in	ADP
ecletica-1594	292	25	quantitative	quantitative	ADJ
ecletica-1594	292	26	structure	structure	NOUN
ecletica-1594	292	27	activity	activity	NOUN
ecletica-1594	292	28	and	and	CCONJ
ecletica-1594	292	29	structure	structure	NOUN
ecletica-1594	292	30	property	property	NOUN
ecletica-1594	292	31	relationship	relationship	NOUN
ecletica-1594	292	32	.	.	PUNCT
ecletica-1594	293	1	chemical	chemical	PROPN
ecletica-1594	293	2	physics	physics	PROPN
ecletica-1594	293	3	letter	letter	NOUN
ecletica-1594	293	4	.	.	PUNCT
ecletica-1594	294	1	2000	2000	NUM
ecletica-1594	294	2	,	,	PUNCT
ecletica-1594	294	3	323	323	NUM
ecletica-1594	294	4	(	(	PUNCT
ecletica-1594	294	5	1	1	NUM
ecletica-1594	294	6	-	-	SYM
ecletica-1594	294	7	2	2	NUM
ecletica-1594	294	8	)	)	PUNCT
ecletica-1594	294	9	,	,	PUNCT
ecletica-1594	294	10	59	59	NUM
ecletica-1594	294	11	–	–	SYM
ecletica-1594	294	12	70	70	NUM
ecletica-1594	294	13	.	.	PUNCT
ecletica-1594	295	1	https://doi.org/10.1016/s0009-2614(00)00488-7	https://doi.org/10.1016/s0009-2614(00)00488-7	PROPN
ecletica-1594	295	2	trott	trott	PROPN
ecletica-1594	295	3	,	,	PUNCT
ecletica-1594	295	4	o.	o.	PROPN
ecletica-1594	295	5	;	;	PUNCT
ecletica-1594	295	6	olson	olson	NOUN
ecletica-1594	295	7	,	,	PUNCT
ecletica-1594	295	8	a.	a.	PROPN
ecletica-1594	295	9	j.	j.	PROPN
ecletica-1594	295	10	autodock	autodock	PROPN
ecletica-1594	295	11	vina	vina	PROPN
ecletica-1594	295	12	:	:	PUNCT
ecletica-1594	295	13	improving	improve	VERB
ecletica-1594	295	14	the	the	DET
ecletica-1594	295	15	speed	speed	NOUN
ecletica-1594	295	16	and	and	CCONJ
ecletica-1594	295	17	accuracy	accuracy	NOUN
ecletica-1594	295	18	of	of	ADP
ecletica-1594	295	19	docking	docking	NOUN
ecletica-1594	295	20	with	with	ADP
ecletica-1594	295	21	a	a	DET
ecletica-1594	295	22	new	new	ADJ
ecletica-1594	295	23	scoring	scoring	NOUN
ecletica-1594	295	24	function	function	NOUN
ecletica-1594	295	25	,	,	PUNCT
ecletica-1594	295	26	efficient	efficient	ADJ
ecletica-1594	295	27	optimization	optimization	NOUN
ecletica-1594	295	28	and	and	CCONJ
ecletica-1594	295	29	multithreading	multithreade	VERB
ecletica-1594	295	30	.	.	PUNCT
ecletica-1594	296	1	journal	journal	NOUN
ecletica-1594	296	2	of	of	ADP
ecletica-1594	296	3	computational	computational	ADJ
ecletica-1594	296	4	chemistry	chemistry	NOUN
ecletica-1594	296	5	.	.	PUNCT
ecletica-1594	297	1	2010	2010	NUM
ecletica-1594	297	2	,	,	PUNCT
ecletica-1594	297	3	31	31	NUM
ecletica-1594	297	4	,	,	PUNCT
ecletica-1594	297	5	455–461	455–461	NUM
ecletica-1594	297	6	.	.	PUNCT
ecletica-1594	298	1	https://doi.org/10.1002/jcc.21334	https://doi.org/10.1002/jcc.21334	PROPN
ecletica-1594	298	2	hehre	hehre	PROPN
ecletica-1594	298	3	,	,	PUNCT
ecletica-1594	298	4	w.	w.	PROPN
ecletica-1594	298	5	j.	j.	PROPN
ecletica-1594	298	6	;	;	PUNCT
ecletica-1594	298	7	radom	radom	PROPN
ecletica-1594	298	8	,	,	PUNCT
ecletica-1594	298	9	l.	l.	PROPN
ecletica-1594	298	10	;	;	PUNCT
ecletica-1594	298	11	schleyer	schleyer	PROPN
ecletica-1594	298	12	,	,	PUNCT
ecletica-1594	298	13	p.	p.	NOUN
ecletica-1594	298	14	v.	v.	PROPN
ecletica-1594	298	15	r.	r.	PROPN
ecletica-1594	298	16	;	;	PUNCT
ecletica-1594	298	17	pope	pope	PROPN
ecletica-1594	298	18	,	,	PUNCT
ecletica-1594	298	19	j.	j.	PROPN
ecletica-1594	298	20	a.	a.	PROPN
ecletica-1594	298	21	ab	ab	PROPN
ecletica-1594	298	22	initio	initio	PROPN
ecletica-1594	298	23	molecular	molecular	ADJ
ecletica-1594	298	24	orbital	orbital	ADJ
ecletica-1594	298	25	theory	theory	NOUN
ecletica-1594	298	26	,	,	PUNCT
ecletica-1594	298	27	wiley	wiley	PROPN
ecletica-1594	298	28	,	,	PUNCT
ecletica-1594	298	29	new	new	PROPN
ecletica-1594	298	30	york	york	PROPN
ecletica-1594	298	31	,	,	PUNCT
ecletica-1594	298	32	1988	1988	NUM
ecletica-1594	298	33	waring	waring	NOUN
ecletica-1594	298	34	,	,	PUNCT
ecletica-1594	298	35	m.	m.	NOUN
ecletica-1594	298	36	j.	j.	PROPN
ecletica-1594	298	37	;	;	PUNCT
ecletica-1594	298	38	arrowsmith	arrowsmith	PROPN
ecletica-1594	298	39	,	,	PUNCT
ecletica-1594	298	40	j.	j.	PROPN
ecletica-1594	298	41	;	;	PUNCT
ecletica-1594	298	42	leach	leach	NOUN
ecletica-1594	298	43	,	,	PUNCT
ecletica-1594	298	44	a.	a.	PROPN
ecletica-1594	298	45	r.	r.	PROPN
ecletica-1594	298	46	;	;	PUNCT
ecletica-1594	298	47	leeson	leeson	PROPN
ecletica-1594	298	48	,	,	PUNCT
ecletica-1594	298	49	p.	p.	PROPN
ecletica-1594	298	50	d.	d.	PROPN
ecletica-1594	298	51	;	;	PUNCT
ecletica-1594	299	1	mandrell	mandrell	PROPN
ecletica-1594	299	2	,	,	PUNCT
ecletica-1594	299	3	s.	s.	PROPN
ecletica-1594	299	4	;	;	PUNCT
ecletica-1594	299	5	owen	owen	PROPN
ecletica-1594	299	6	,	,	PUNCT
ecletica-1594	299	7	r.	r.	PROPN
ecletica-1594	299	8	m.	m.	PROPN
ecletica-1594	299	9	an	an	DET
ecletica-1594	299	10	analysis	analysis	NOUN
ecletica-1594	299	11	of	of	ADP
ecletica-1594	299	12	the	the	DET
ecletica-1594	299	13	attrition	attrition	NOUN
ecletica-1594	299	14	of	of	ADP
ecletica-1594	299	15	drug	drug	NOUN
ecletica-1594	299	16	candidates	candidate	NOUN
ecletica-1594	299	17	from	from	ADP
ecletica-1594	299	18	four	four	NUM
ecletica-1594	299	19	major	major	ADJ
ecletica-1594	299	20	pharmaceutical	pharmaceutical	ADJ
ecletica-1594	299	21	companies	company	NOUN
ecletica-1594	299	22	.	.	PUNCT
ecletica-1594	300	1	nat	nat	PROPN
ecletica-1594	300	2	.	.	PUNCT
ecletica-1594	301	1	rev	rev	PROPN
ecletica-1594	301	2	.	.	PROPN
ecletica-1594	301	3	drug	drug	PROPN
ecletica-1594	301	4	.	.	PUNCT
ecletica-1594	302	1	discov	discov	NOUN
ecletica-1594	302	2	.	.	PUNCT
ecletica-1594	303	1	2015	2015	NUM
ecletica-1594	303	2	,	,	PUNCT
ecletica-1594	303	3	14	14	NUM
ecletica-1594	303	4	,	,	PUNCT
ecletica-1594	303	5	475	475	NUM
ecletica-1594	303	6	–	–	PUNCT
ecletica-1594	303	7	486	486	NUM
ecletica-1594	303	8	.	.	PUNCT
ecletica-1594	304	1	https://doi.org/10.1038/nrd4609	https://doi.org/10.1038/nrd4609	PROPN
ecletica-1594	304	2	wertheim	wertheim	PROPN
ecletica-1594	304	3	,	,	PUNCT
ecletica-1594	304	4	h.	h.	PROPN
ecletica-1594	304	5	f.	f.	PROPN
ecletica-1594	304	6	;	;	PUNCT
ecletica-1594	304	7	melles	melle	NOUN
ecletica-1594	304	8	,	,	PUNCT
ecletica-1594	304	9	d.	d.	PROPN
ecletica-1594	304	10	c.	c.	PROPN
ecletica-1594	304	11	;	;	PUNCT
ecletica-1594	304	12	vos	vos	PROPN
ecletica-1594	304	13	,	,	PUNCT
ecletica-1594	304	14	m.	m.	NOUN
ecletica-1594	304	15	c.	c.	PROPN
ecletica-1594	304	16	;	;	PUNCT
ecletica-1594	304	17	van	van	PROPN
ecletica-1594	304	18	leeuwen	leeuwen	PROPN
ecletica-1594	304	19	,	,	PUNCT
ecletica-1594	304	20	w.	w.	PROPN
ecletica-1594	304	21	;	;	PUNCT
ecletica-1594	304	22	van	van	PROPN
ecletica-1594	304	23	belkum	belkum	NOUN
ecletica-1594	304	24	,	,	PUNCT
ecletica-1594	304	25	a.	a.	NOUN
ecletica-1594	304	26	;	;	PUNCT
ecletica-1594	304	27	verbrugh	verbrugh	PROPN
ecletica-1594	304	28	,	,	PUNCT
ecletica-1594	304	29	h.	h.	PROPN
ecletica-1594	304	30	a.	a.	PROPN
ecletica-1594	304	31	;	;	PUNCT
ecletica-1594	304	32	nouwen	nouwen	PROPN
ecletica-1594	304	33	,	,	PUNCT
ecletica-1594	304	34	j.	j.	PROPN
ecletica-1594	304	35	l.	l.	PROPN
ecletica-1594	304	36	the	the	DET
ecletica-1594	304	37	role	role	NOUN
ecletica-1594	304	38	of	of	ADP
ecletica-1594	304	39	nasal	nasal	PROPN
ecletica-1594	304	40	carriage	carriage	NOUN
ecletica-1594	304	41	in	in	ADP
ecletica-1594	304	42	staphylococcus	staphylococcus	NOUN
ecletica-1594	304	43	aureus	aureus	NOUN
ecletica-1594	304	44	infections	infection	NOUN
ecletica-1594	304	45	.	.	PUNCT
ecletica-1594	305	1	lancet	lancet	PROPN
ecletica-1594	305	2	infect	infect	PROPN
ecletica-1594	305	3	dis	dis	PROPN
ecletica-1594	305	4	.	.	PUNCT
ecletica-1594	306	1	2005	2005	NUM
ecletica-1594	306	2	,	,	PUNCT
ecletica-1594	306	3	5	5	NUM
ecletica-1594	306	4	(	(	PUNCT
ecletica-1594	306	5	12	12	NUM
ecletica-1594	306	6	)	)	PUNCT
ecletica-1594	306	7	,	,	PUNCT
ecletica-1594	306	8	751–762	751–762	NUM
ecletica-1594	306	9	.	.	PUNCT
ecletica-1594	307	1	https://doi.org/10.1016/s1473-3099(05)70295-4	https://doi.org/10.1016/s1473-3099(05)70295-4	PROPN
ecletica-1594	307	2	winum	winum	PROPN
ecletica-1594	307	3	,	,	PUNCT
ecletica-1594	307	4	j.	j.	PROPN
ecletica-1594	307	5	y.	y.	PROPN
ecletica-1594	307	6	;	;	PUNCT
ecletica-1594	307	7	scozzafava	scozzafava	NOUN
ecletica-1594	307	8	,	,	PUNCT
ecletica-1594	307	9	a.	a.	PROPN
ecletica-1594	307	10	;	;	PUNCT
ecletica-1594	307	11	montero	montero	PROPN
ecletica-1594	307	12	,	,	PUNCT
ecletica-1594	307	13	j.	j.	PROPN
ecletica-1594	307	14	l.	l.	PROPN
ecletica-1594	307	15	;	;	PUNCT
ecletica-1594	307	16	supuran	supuran	NOUN
ecletica-1594	307	17	,	,	PUNCT
ecletica-1594	307	18	c.	c.	PROPN
ecletica-1594	307	19	t.	t.	PROPN
ecletica-1594	307	20	therapeutic	therapeutic	ADJ
ecletica-1594	307	21	potential	potential	NOUN
ecletica-1594	307	22	of	of	ADP
ecletica-1594	307	23	sulfamides	sulfamide	NOUN
ecletica-1594	307	24	as	as	ADP
ecletica-1594	307	25	enzyme	enzyme	NOUN
ecletica-1594	307	26	inhibitors	inhibitor	NOUN
ecletica-1594	307	27	.	.	PUNCT
ecletica-1594	308	1	med	med	PROPN
ecletica-1594	308	2	.	.	PUNCT
ecletica-1594	309	1	res	re	NOUN
ecletica-1594	309	2	.	.	PUNCT
ecletica-1594	310	1	rev	rev	PROPN
ecletica-1594	310	2	.	.	PROPN
ecletica-1594	310	3	2006	2006	NUM
ecletica-1594	310	4	,	,	PUNCT
ecletica-1594	310	5	26	26	NUM
ecletica-1594	310	6	(	(	PUNCT
ecletica-1594	310	7	6	6	NUM
ecletica-1594	310	8	)	)	PUNCT
ecletica-1594	310	9	,	,	PUNCT
ecletica-1594	310	10	767–792	767–792	NUM
ecletica-1594	310	11	.	.	PUNCT
ecletica-1594	311	1	https://doi.org/10.1002/med.20068	https://doi.org/10.1002/med.20068	PROPN
ecletica-1594	311	2	yang	yang	PROPN
ecletica-1594	311	3	,	,	PUNCT
ecletica-1594	311	4	l.	l.	PROPN
ecletica-1594	311	5	;	;	PUNCT
ecletica-1594	311	6	feng	feng	PROPN
ecletica-1594	311	7	,	,	PUNCT
ecletica-1594	311	8	j.	j.	PROPN
ecletica-1594	311	9	;	;	PUNCT
ecletica-1594	311	10	ren	ren	PROPN
ecletica-1594	311	11	,	,	PUNCT
ecletica-1594	311	12	a.	a.	PROPN
ecletica-1594	311	13	theoretical	theoretical	ADJ
ecletica-1594	311	14	studies	study	NOUN
ecletica-1594	311	15	on	on	ADP
ecletica-1594	311	16	the	the	DET
ecletica-1594	311	17	electronic	electronic	ADJ
ecletica-1594	311	18	and	and	CCONJ
ecletica-1594	311	19	optical	optical	ADJ
ecletica-1594	311	20	properties	property	NOUN
ecletica-1594	311	21	of	of	ADP
ecletica-1594	311	22	two	two	NUM
ecletica-1594	311	23	thiophene	thiophene	NOUN
ecletica-1594	311	24	–	–	PUNCT
ecletica-1594	311	25	fluorene	fluorene	NOUN
ecletica-1594	311	26	based	base	VERB
ecletica-1594	311	27	π	π	PROPN
ecletica-1594	311	28	-	-	PUNCT
ecletica-1594	311	29	conjugated	conjugate	VERB
ecletica-1594	311	30	copolymers	copolymer	NOUN
ecletica-1594	311	31	.	.	PUNCT
ecletica-1594	312	1	polymer	polymer	NOUN
ecletica-1594	312	2	.	.	PUNCT
ecletica-1594	313	1	2005	2005	NUM
ecletica-1594	313	2	,	,	PUNCT
ecletica-1594	313	3	46	46	NUM
ecletica-1594	313	4	(	(	PUNCT
ecletica-1594	313	5	24	24	NUM
ecletica-1594	313	6	)	)	PUNCT
ecletica-1594	313	7	,	,	PUNCT
ecletica-1594	313	8	10970–10982	10970–10982	NUM
ecletica-1594	313	9	.	.	PUNCT
ecletica-1594	314	1	https://doi.org/10.1016/j.polymer.2005.09.050	https://doi.org/10.1016/j.polymer.2005.09.050	PROPN
ecletica-1594	314	2	zhao	zhao	PROPN
ecletica-1594	314	3	,	,	PUNCT
ecletica-1594	314	4	c.	c.	PROPN
ecletica-1594	314	5	;	;	PUNCT
ecletica-1594	314	6	rakesh	rakesh	PROPN
ecletica-1594	314	7	,	,	PUNCT
ecletica-1594	314	8	k.	k.	PROPN
ecletica-1594	314	9	p.	p.	PROPN
ecletica-1594	314	10	;	;	PUNCT
ecletica-1594	314	11	ravidar	ravidar	NOUN
ecletica-1594	314	12	,	,	PUNCT
ecletica-1594	314	13	l.	l.	PROPN
ecletica-1594	314	14	;	;	PUNCT
ecletica-1594	314	15	fang	fang	PROPN
ecletica-1594	314	16	,	,	PUNCT
ecletica-1594	314	17	w.	w.	PROPN
ecletica-1594	314	18	y.	y.	PROPN
ecletica-1594	314	19	;	;	PUNCT
ecletica-1594	314	20	qin	qin	PROPN
ecletica-1594	314	21	,	,	PUNCT
ecletica-1594	314	22	h.	h.	PROPN
ecletica-1594	314	23	l.	l.	PROPN
ecletica-1594	314	24	pharmaceutical	pharmaceutical	PROPN
ecletica-1594	314	25	and	and	CCONJ
ecletica-1594	314	26	medicinal	medicinal	ADJ
ecletica-1594	314	27	significance	significance	NOUN
ecletica-1594	314	28	of	of	ADP
ecletica-1594	314	29	sulfur	sulfur	NOUN
ecletica-1594	314	30	(	(	PUNCT
ecletica-1594	314	31	svi)-containing	svi)-containe	VERB
ecletica-1594	314	32	motifs	motif	NOUN
ecletica-1594	314	33	for	for	ADP
ecletica-1594	314	34	drug	drug	NOUN
ecletica-1594	314	35	discovery	discovery	NOUN
ecletica-1594	314	36	:	:	PUNCT
ecletica-1594	314	37	a	a	DET
ecletica-1594	314	38	critical	critical	ADJ
ecletica-1594	314	39	review	review	NOUN
ecletica-1594	314	40	.	.	PUNCT
ecletica-1594	315	1	eur	eur	PROPN
ecletica-1594	315	2	.	.	PUNCT
ecletica-1594	316	1	j.	j.	PROPN
ecletica-1594	316	2	med	med	PROPN
ecletica-1594	316	3	.	.	PROPN
ecletica-1594	316	4	chem	chem	PROPN
ecletica-1594	316	5	.	.	PUNCT
ecletica-1594	317	1	2019	2019	NUM
ecletica-1594	317	2	,	,	PUNCT
ecletica-1594	317	3	162	162	NUM
ecletica-1594	317	4	,	,	PUNCT
ecletica-1594	317	5	679−734	679−734	NUM
ecletica-1594	317	6	.	.	X
ecletica-1594	318	1	https://doi.org/10.1016/j.ejmech.2018.11.017	https://doi.org/10.1016/j.ejmech.2018.11.017	X
ecletica-1594	318	2	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	X
ecletica-1594	318	3	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	https://doi.org/10.26850/1678-4618.eq.v50.2025.e1594	X
ecletica-1594	318	4	https://doi.org/10.1038/srep42717	https://doi.org/10.1038/srep42717	PROPN
ecletica-1594	318	5	https://doi.org/10.2174/1568026023392841	https://doi.org/10.2174/1568026023392841	PROPN
ecletica-1594	318	6	https://doi.org/10.2174/1385272822666180122153839	https://doi.org/10.2174/1385272822666180122153839	PROPN
ecletica-1594	318	7	https://doi.org/10.3390/molecules24183312	https://doi.org/10.3390/molecules24183312	PROPN
ecletica-1594	318	8	https://doi.org/10.1128/aac.01658-08	https://doi.org/10.1128/aac.01658-08	PROPN
ecletica-1594	318	9	https://doi.org/10.2174/187152008785914806	https://doi.org/10.2174/187152008785914806	NOUN
ecletica-1594	318	10	https://doi.org/10.1016/j.ejmech.2012.01.060	https://doi.org/10.1016/j.ejmech.2012.01.060	NOUN
ecletica-1594	318	11	https://doi.org/10.1016/j.ddtec.2004.11.007	https://doi.org/10.1016/j.ddtec.2004.11.007	VERB
ecletica-1594	318	12	https://doi.org/10.29356/jmcs.v64i3.1167	https://doi.org/10.29356/jmcs.v64i3.1167	ADJ
ecletica-1594	318	13	https://doi.org/10.1001/archinte.163.4.402	https://doi.org/10.1001/archinte.163.4.402	NOUN
ecletica-1594	318	14	https://doi.org/10.1007/s42250-021-00276-2	https://doi.org/10.1007/s42250-021-00276-2	X
ecletica-1594	318	15	https://doi.org/10.7537/marscbj06021610	https://doi.org/10.7537/marscbj06021610	PROPN
ecletica-1594	318	16	https://doi.org/10.33263/lianbs124.113	https://doi.org/10.33263/lianbs124.113	ADJ
ecletica-1594	318	17	https://doi.org/10.1021/ja983494x	https://doi.org/10.1021/ja983494x	NUM
ecletica-1594	318	18	https://doi.org/10.1016/j.comptc.2023.114211	https://doi.org/10.1016/j.comptc.2023.114211	PROPN
ecletica-1594	318	19	https://doi.org/10.1016/j.meegid.2013.08.018	https://doi.org/10.1016/j.meegid.2013.08.018	VERB
ecletica-1594	318	20	https://doi.org/10.1021/acsomega.1c04552	https://doi.org/10.1021/acsomega.1c04552	ADJ
ecletica-1594	318	21	https://doi.org/10.1016/j.apsb.2022.02.002	https://doi.org/10.1016/j.apsb.2022.02.002	NOUN
ecletica-1594	318	22	https://doi.org/10.3390/molecules22101642	https://doi.org/10.3390/molecules22101642	VERB
ecletica-1594	318	23	https://doi.org/10.1016/s0009-2614(00)00488-7	https://doi.org/10.1016/s0009-2614(00)00488-7	PROPN
ecletica-1594	318	24	https://doi.org/10.1002/jcc.21334	https://doi.org/10.1002/jcc.21334	PROPN
ecletica-1594	318	25	https://doi.org/10.1038/nrd4609	https://doi.org/10.1038/nrd4609	PROPN
ecletica-1594	318	26	https://doi.org/10.1016/s1473-3099(05)70295-4	https://doi.org/10.1016/s1473-3099(05)70295-4	PROPN
ecletica-1594	318	27	https://doi.org/10.1002/med.20068	https://doi.org/10.1002/med.20068	PROPN
ecletica-1594	318	28	https://doi.org/10.1016/j.polymer.2005.09.050	https://doi.org/10.1016/j.polymer.2005.09.050	PROPN
ecletica-1594	318	29	https://doi.org/10.1016/j.ejmech.2018.11.017	https://doi.org/10.1016/j.ejmech.2018.11.017	NUM