Editorial 

revista.iq.unesp.br 

| Vol. 47 | n. 2 | 2022 | 

 
 

 

 

Editorial 

The Editor of Eclética Química Journal proudly announces the second issue of 2022. In this issue the readers 

find a first article describing a chemoenzymatic approach for the synthesis of eight α-N-heterocyclic ethyl- and 

phenylacetamides and screening of twenty nitrile hydratases. The authors evaluated different proportions of ionic 

liquids and polyethylene glycol as potential green solvents to substitute aqueous buffered solutions to avoid a retro-

Strecker reaction of α-aminonitriles and the effect of temperature to optimize the process. The use of unconventional 

reaction media and low temperatures reduced the nitrile hydratases activity. The absolute configuration of the 

compounds was determined by electronic circular dichroism spectroscopy and the racemic levetiracetam derivatives 

showed non inhibitory effect on cholinesterase. Follow, it is presented a quick and straightforward methodology to 

separate lactic acid and glycerol by high-performance liquid chromatography (HPLC). Glycerol is a by-product of 

biodiesel obtention and its conversion to lactic acid makes the glycerol industry more profitable, since lactic acid is 

applied in the textile, cosmetic and food industries, in the synthesis of polylactic acid and as precursor of solvents in 

green chemistry. A central composite design (CCD) was proposed to study the influence of experimental variables 

on glycerolysis reaction and HPLC was used to separate and quantify lactic acid. The next article describes the 

adsorbent efficiency of sugarcane bagasse biochar for removal of caffeine, ciprofloxacin, and norfloxacin from 

wastewater. The biochar, without chemical and physical activation, was obtained from sugarcane by torrefaction at 

different temperatures from 260 to 290 oC and characterized by different spectroscopic, microscopic and thermal 

analysis techniques besides point of zero charge, pH, elemental composition, and surface area determination. The 

biochar prepared at 280 oC showed the best stability and higher performance in the adsorption of pharmaceutical 

compounds. Complete this issue, considerations to elucidate some understanding about two metastable phases found 

in a rapid quenched alloy from Ni-Nb-Zr system during the solidification process. Metastable phases are formed 

when materials are produced out of the equilibrium conditions, and there is no universal knowledge related to the 

formation of these phases, but the understanding of metastable phases formation can produce and improve promising 

technological materials. The hypothesis discussed consider free energies of formation among phases which compete 

to nucleate, stability of crystalline phases at nanoscale and atomic pair preferences during the nucleation. 

The Editor and his team wish to express their sincere thanks to the authors and reviewers for their outstanding 

collaboration and kindly invite you to submit your manuscript to Eclética Química Journal. 

 

Assis Vicente Benedetti 

Editor-in-Chief of EQJ 

https://revista.iq.unesp.br/index.php/ecletica