id	sid	tid	token	lemma	pos
easat-264	1	1	edelweiss	edelweiss	PROPN
easat-264	1	2	applied	apply	VERB
easat-264	1	3	science	science	NOUN
easat-264	1	4	and	and	CCONJ
easat-264	1	5	technology	technology	NOUN
easat-264	1	6	issn	issn	PROPN
easat-264	1	7	:	:	PUNCT
easat-264	1	8	2576	2576	NUM
easat-264	1	9	-	-	SYM
easat-264	1	10	8484	8484	NUM
easat-264	1	11	vol	vol	NOUN
easat-264	1	12	.	.	PROPN
easat-264	2	1	3	3	NUM
easat-264	2	2	,	,	PUNCT
easat-264	2	3	no	no	INTJ
easat-264	2	4	.	.	NOUN
easat-264	2	5	1	1	NUM
easat-264	2	6	,	,	PUNCT
easat-264	2	7	26	26	NUM
easat-264	2	8	-	-	SYM
easat-264	2	9	29	29	NUM
easat-264	2	10	2019	2019	NUM
easat-264	2	11	doi	doi	NOUN
easat-264	2	12	:	:	PUNCT
easat-264	2	13	10.33805/2576	10.33805/2576	NUM
easat-264	2	14	-	-	SYM
easat-264	2	15	8484.164	8484.164	NUM
easat-264	2	16	©	©	ADP
easat-264	2	17	2019	2019	NUM
easat-264	2	18	by	by	ADP
easat-264	2	19	the	the	DET
easat-264	2	20	author	author	NOUN
easat-264	2	21	©	©	PROPN
easat-264	2	22	2019	2019	NUM
easat-264	2	23	by	by	ADP
easat-264	2	24	the	the	DET
easat-264	2	25	author	author	NOUN
easat-264	2	26	history	history	NOUN
easat-264	2	27	:	:	PUNCT
easat-264	2	28	received	receive	VERB
easat-264	2	29	:	:	PUNCT
easat-264	2	30	4	4	NUM
easat-264	2	31	july	july	PROPN
easat-264	2	32	2019	2019	NUM
easat-264	2	33	;	;	PUNCT
easat-264	2	34	accepted	accept	VERB
easat-264	2	35	:	:	PUNCT
easat-264	2	36	5	5	NUM
easat-264	2	37	august	august	PROPN
easat-264	2	38	2019	2019	NUM
easat-264	2	39	;	;	PUNCT
easat-264	2	40	published	publish	VERB
easat-264	2	41	:	:	PUNCT
easat-264	2	42	9	9	NUM
easat-264	2	43	august	august	PROPN
easat-264	2	44	2019	2019	NUM
easat-264	2	45	*	*	PUNCT
easat-264	2	46	correspondence	correspondence	NOUN
easat-264	2	47	:	:	PUNCT
easat-264	2	48	info@ebma-europe.com	info@ebma-europe.com	X
easat-264	2	49	the	the	DET
easat-264	2	50	bio	bio	NOUN
easat-264	2	51	immune(g)ene	immune(g)ene	ADJ
easat-264	2	52	medicine	medicine	NOUN
easat-264	2	53	or	or	CCONJ
easat-264	2	54	how	how	SCONJ
easat-264	2	55	to	to	PART
easat-264	2	56	use	use	VERB
easat-264	2	57	a	a	DET
easat-264	2	58	maximum	maximum	NOUN
easat-264	2	59	of	of	ADP
easat-264	2	60	molecular	molecular	ADJ
easat-264	2	61	resources	resource	NOUN
easat-264	2	62	of	of	ADP
easat-264	2	63	the	the	DET
easat-264	2	64	cell	cell	NOUN
easat-264	2	65	for	for	ADP
easat-264	2	66	therapeutic	therapeutic	ADJ
easat-264	2	67	purposes	purpose	NOUN
easat-264	2	68	glady	glady	VERB
easat-264	2	69	gilbert	gilbert	PROPN
easat-264	2	70	president	president	PROPN
easat-264	2	71	of	of	ADP
easat-264	2	72	european	european	PROPN
easat-264	2	73	bio	bio	PROPN
easat-264	2	74	immune	immune	PROPN
easat-264	2	75	(	(	PUNCT
easat-264	2	76	g)ene	g)ene	NOUN
easat-264	2	77	medicine	medicine	NOUN
easat-264	2	78	association	association	NOUN
easat-264	2	79	(	(	PUNCT
easat-264	2	80	ebma	ebma	PROPN
easat-264	2	81	)	)	PUNCT
easat-264	2	82	,	,	PUNCT
easat-264	2	83	france	france	PROPN
easat-264	2	84	;	;	PUNCT
easat-264	2	85	info@ebma-europe.com	info@ebma-europe.com	PROPN
easat-264	2	86	(	(	PUNCT
easat-264	2	87	g.g	g.g	PROPN
easat-264	2	88	.	.	PROPN
easat-264	2	89	)	)	PUNCT
easat-264	2	90	.	.	PUNCT
easat-264	3	1	abstract	abstract	ADV
easat-264	3	2	:	:	PUNCT
easat-264	3	3	at	at	ADP
easat-264	3	4	a	a	DET
easat-264	3	5	time	time	NOUN
easat-264	3	6	when	when	SCONJ
easat-264	3	7	emerging	emerge	VERB
easat-264	3	8	concepts	concept	NOUN
easat-264	3	9	capable	capable	ADJ
easat-264	3	10	of	of	ADP
easat-264	3	11	revolutionizing	revolutionize	VERB
easat-264	3	12	old	old	ADJ
easat-264	3	13	medical	medical	ADJ
easat-264	3	14	paradigms	paradigm	NOUN
easat-264	3	15	are	be	AUX
easat-264	3	16	flourishing	flourish	VERB
easat-264	3	17	,	,	PUNCT
easat-264	3	18	such	such	ADJ
easat-264	3	19	as	as	ADP
easat-264	3	20	systems	system	NOUN
easat-264	3	21	biology	biology	NOUN
easat-264	3	22	,	,	PUNCT
easat-264	3	23	integrative	integrative	ADJ
easat-264	3	24	medicine	medicine	NOUN
easat-264	3	25	or	or	CCONJ
easat-264	3	26	personalized	personalized	ADJ
easat-264	3	27	medicine	medicine	NOUN
easat-264	3	28	,	,	PUNCT
easat-264	3	29	it	it	PRON
easat-264	3	30	is	be	AUX
easat-264	3	31	of	of	ADP
easat-264	3	32	the	the	DET
easat-264	3	33	utmost	utmost	ADJ
easat-264	3	34	interest	interest	NOUN
easat-264	3	35	to	to	PART
easat-264	3	36	observe	observe	VERB
easat-264	3	37	how	how	SCONJ
easat-264	3	38	such	such	ADJ
easat-264	3	39	concepts	concept	NOUN
easat-264	3	40	can	can	AUX
easat-264	3	41	be	be	AUX
easat-264	3	42	applied	apply	VERB
easat-264	3	43	in	in	ADP
easat-264	3	44	the	the	DET
easat-264	3	45	context	context	NOUN
easat-264	3	46	of	of	ADP
easat-264	3	47	a	a	DET
easat-264	3	48	therapeutic	therapeutic	ADJ
easat-264	3	49	method	method	NOUN
easat-264	3	50	that	that	PRON
easat-264	3	51	is	be	AUX
easat-264	3	52	both	both	CCONJ
easat-264	3	53	innovative	innovative	ADJ
easat-264	3	54	and	and	CCONJ
easat-264	3	55	devoid	devoid	ADJ
easat-264	3	56	of	of	ADP
easat-264	3	57	any	any	DET
easat-264	3	58	undesirable	undesirable	ADJ
easat-264	3	59	effect	effect	NOUN
easat-264	3	60	,	,	PUNCT
easat-264	3	61	because	because	SCONJ
easat-264	3	62	it	it	PRON
easat-264	3	63	simply	simply	ADV
easat-264	3	64	seeks	seek	VERB
easat-264	3	65	to	to	PART
easat-264	3	66	play	play	VERB
easat-264	3	67	a	a	DET
easat-264	3	68	regulatory	regulatory	ADJ
easat-264	3	69	role	role	NOUN
easat-264	3	70	.	.	PUNCT
easat-264	4	1	the	the	DET
easat-264	4	2	aim	aim	NOUN
easat-264	4	3	of	of	ADP
easat-264	4	4	this	this	DET
easat-264	4	5	method	method	NOUN
easat-264	4	6	called	call	VERB
easat-264	4	7	bio	bio	PROPN
easat-264	4	8	immune(g)ene	immune(g)ene	ADJ
easat-264	4	9	medicine	medicine	NOUN
easat-264	4	10	(	(	PUNCT
easat-264	4	11	bi(g)med	bi(g)me	VERB
easat-264	4	12	)	)	PUNCT
easat-264	4	13	is	be	AUX
easat-264	4	14	to	to	PART
easat-264	4	15	make	make	VERB
easat-264	4	16	the	the	DET
easat-264	4	17	best	good	ADJ
easat-264	4	18	use	use	NOUN
easat-264	4	19	of	of	ADP
easat-264	4	20	all	all	DET
easat-264	4	21	the	the	DET
easat-264	4	22	molecular	molecular	ADJ
easat-264	4	23	resources	resource	NOUN
easat-264	4	24	available	available	ADJ
easat-264	4	25	to	to	ADP
easat-264	4	26	the	the	DET
easat-264	4	27	cell	cell	NOUN
easat-264	4	28	to	to	PART
easat-264	4	29	restore	restore	VERB
easat-264	4	30	the	the	DET
easat-264	4	31	homeostasis	homeostasis	NOUN
easat-264	4	32	of	of	ADP
easat-264	4	33	the	the	DET
easat-264	4	34	latter	latter	ADJ
easat-264	4	35	at	at	ADP
easat-264	4	36	its	its	PRON
easat-264	4	37	various	various	ADJ
easat-264	4	38	levels	level	NOUN
easat-264	4	39	of	of	ADP
easat-264	4	40	genome	genome	NOUN
easat-264	4	41	,	,	PUNCT
easat-264	4	42	epigenome	epigenome	NOUN
easat-264	4	43	,	,	PUNCT
easat-264	4	44	transcriptome	transcriptome	NOUN
easat-264	4	45	,	,	PUNCT
easat-264	4	46	proteome	proteome	NOUN
easat-264	4	47	and	and	CCONJ
easat-264	4	48	metabolome	metabolome	NOUN
easat-264	4	49	.	.	PUNCT
easat-264	5	1	to	to	PART
easat-264	5	2	achieve	achieve	VERB
easat-264	5	3	this	this	DET
easat-264	5	4	goal	goal	NOUN
easat-264	5	5	,	,	PUNCT
easat-264	5	6	it	it	PRON
easat-264	5	7	is	be	AUX
easat-264	5	8	of	of	ADP
easat-264	5	9	course	course	NOUN
easat-264	5	10	essential	essential	ADJ
easat-264	5	11	to	to	PART
easat-264	5	12	use	use	VERB
easat-264	5	13	means	mean	NOUN
easat-264	5	14	borrowed	borrow	VERB
easat-264	5	15	to	to	ADP
easat-264	5	16	nanobiotechnologies	nanobiotechnologie	NOUN
easat-264	5	17	to	to	PART
easat-264	5	18	ensure	ensure	VERB
easat-264	5	19	a	a	DET
easat-264	5	20	high	high	ADJ
easat-264	5	21	efficiency	efficiency	NOUN
easat-264	5	22	of	of	ADP
easat-264	5	23	the	the	DET
easat-264	5	24	molecules	molecule	NOUN
easat-264	5	25	made	make	VERB
easat-264	5	26	available	available	ADJ
easat-264	5	27	to	to	ADP
easat-264	5	28	the	the	DET
easat-264	5	29	cells	cell	NOUN
easat-264	5	30	to	to	PART
easat-264	5	31	facilitate	facilitate	VERB
easat-264	5	32	their	their	PRON
easat-264	5	33	self	self	NOUN
easat-264	5	34	-	-	PUNCT
easat-264	5	35	regulation	regulation	NOUN
easat-264	5	36	thanks	thank	NOUN
easat-264	5	37	to	to	ADP
easat-264	5	38	a	a	DET
easat-264	5	39	therapeutic	therapeutic	ADJ
easat-264	5	40	model	model	NOUN
easat-264	5	41	essentially	essentially	ADV
easat-264	5	42	based	base	VERB
easat-264	5	43	on	on	ADP
easat-264	5	44	true	true	ADJ
easat-264	5	45	biomimicry	biomimicry	NOUN
easat-264	5	46	.	.	PUNCT
easat-264	6	1	the	the	DET
easat-264	6	2	description	description	NOUN
easat-264	6	3	of	of	ADP
easat-264	6	4	one	one	NUM
easat-264	6	5	or	or	CCONJ
easat-264	6	6	the	the	DET
easat-264	6	7	other	other	ADJ
easat-264	6	8	clinical	clinical	ADJ
easat-264	6	9	case	case	NOUN
easat-264	6	10	will	will	AUX
easat-264	6	11	show	show	VERB
easat-264	6	12	how	how	SCONJ
easat-264	6	13	this	this	DET
easat-264	6	14	method	method	NOUN
easat-264	6	15	can	can	AUX
easat-264	6	16	be	be	AUX
easat-264	6	17	effective	effective	ADJ
easat-264	6	18	in	in	ADP
easat-264	6	19	polypathologies	polypathologie	NOUN
easat-264	6	20	,	,	PUNCT
easat-264	6	21	sometimes	sometimes	ADV
easat-264	6	22	very	very	ADV
easat-264	6	23	advanced	advanced	ADJ
easat-264	6	24	and	and	CCONJ
easat-264	6	25	often	often	ADV
easat-264	6	26	recurrent	recurrent	VERB
easat-264	6	27	,	,	PUNCT
easat-264	6	28	without	without	ADP
easat-264	6	29	ever	ever	ADV
easat-264	6	30	harming	harm	VERB
easat-264	6	31	the	the	DET
easat-264	6	32	patient	patient	NOUN
easat-264	6	33	elsewhere	elsewhere	ADV
easat-264	6	34	.	.	PUNCT
easat-264	7	1	keywords	keyword	NOUN
easat-264	7	2	:	:	PUNCT
easat-264	7	3	bio	bio	PROPN
easat-264	7	4	immune	immune	ADJ
easat-264	7	5	gene	gene	NOUN
easat-264	7	6	,	,	PUNCT
easat-264	7	7	environmental	environmental	ADJ
easat-264	7	8	sciences	science	NOUN
easat-264	7	9	,	,	PUNCT
easat-264	7	10	epigenome	epigenome	NOUN
easat-264	7	11	.	.	PUNCT
easat-264	8	1	1	1	X
easat-264	8	2	.	.	X
easat-264	8	3	introduction	introduction	NOUN
easat-264	8	4	in	in	ADP
easat-264	8	5	recent	recent	ADJ
easat-264	8	6	years	year	NOUN
easat-264	8	7	,	,	PUNCT
easat-264	8	8	new	new	ADJ
easat-264	8	9	concepts	concept	NOUN
easat-264	8	10	have	have	AUX
easat-264	8	11	emerged	emerge	VERB
easat-264	8	12	that	that	PRON
easat-264	8	13	have	have	AUX
easat-264	8	14	led	lead	VERB
easat-264	8	15	to	to	ADP
easat-264	8	16	changes	change	NOUN
easat-264	8	17	in	in	ADP
easat-264	8	18	the	the	DET
easat-264	8	19	way	way	NOUN
easat-264	8	20	the	the	DET
easat-264	8	21	sick	sick	ADJ
easat-264	8	22	individual	individual	NOUN
easat-264	8	23	and	and	CCONJ
easat-264	8	24	the	the	DET
easat-264	8	25	context	context	NOUN
easat-264	8	26	of	of	ADP
easat-264	8	27	his	his	PRON
easat-264	8	28	disease	disease	NOUN
easat-264	8	29	are	be	AUX
easat-264	8	30	approached	approach	VERB
easat-264	8	31	.	.	PUNCT
easat-264	9	1	this	this	PRON
easat-264	9	2	began	begin	VERB
easat-264	9	3	with	with	ADP
easat-264	9	4	a	a	DET
easat-264	9	5	broader	broad	ADJ
easat-264	9	6	approach	approach	NOUN
easat-264	9	7	to	to	ADP
easat-264	9	8	the	the	DET
easat-264	9	9	disease	disease	NOUN
easat-264	9	10	process	process	NOUN
easat-264	9	11	,	,	PUNCT
easat-264	9	12	which	which	PRON
easat-264	9	13	in	in	ADP
easat-264	9	14	some	some	DET
easat-264	9	15	way	way	NOUN
easat-264	9	16	lost	lose	VERB
easat-264	9	17	its	its	PRON
easat-264	9	18	status	status	NOUN
easat-264	9	19	as	as	ADP
easat-264	9	20	an	an	DET
easat-264	9	21	inalienable	inalienable	ADJ
easat-264	9	22	state	state	NOUN
easat-264	9	23	that	that	PRON
easat-264	9	24	can	can	AUX
easat-264	9	25	only	only	ADV
easat-264	9	26	partially	partially	ADV
easat-264	9	27	and	and	CCONJ
easat-264	9	28	temporarily	temporarily	ADV
easat-264	9	29	be	be	AUX
easat-264	9	30	remedied	remedie	VERB
easat-264	9	31	.	.	PUNCT
easat-264	10	1	the	the	DET
easat-264	10	2	disease	disease	NOUN
easat-264	10	3	has	have	AUX
easat-264	10	4	thus	thus	ADV
easat-264	10	5	become	become	VERB
easat-264	10	6	a	a	DET
easat-264	10	7	dynamic	dynamic	ADJ
easat-264	10	8	phenomenon	phenomenon	NOUN
easat-264	10	9	involved	involve	VERB
easat-264	10	10	in	in	ADP
easat-264	10	11	a	a	DET
easat-264	10	12	succession	succession	NOUN
easat-264	10	13	of	of	ADP
easat-264	10	14	pathological	pathological	ADJ
easat-264	10	15	states	state	NOUN
easat-264	10	16	more	more	ADV
easat-264	10	17	or	or	CCONJ
easat-264	10	18	less	less	ADV
easat-264	10	19	reversible	reversible	ADJ
easat-264	10	20	depending	depend	VERB
easat-264	10	21	on	on	ADP
easat-264	10	22	their	their	PRON
easat-264	10	23	greater	great	ADJ
easat-264	10	24	or	or	CCONJ
easat-264	10	25	lesser	less	ADJ
easat-264	10	26	interactivity	interactivity	NOUN
easat-264	10	27	.	.	PUNCT
easat-264	11	1	in	in	ADP
easat-264	11	2	that	that	DET
easat-264	11	3	sense	sense	NOUN
easat-264	11	4	,	,	PUNCT
easat-264	11	5	it	it	PRON
easat-264	11	6	has	have	AUX
easat-264	11	7	been	be	AUX
easat-264	11	8	recently	recently	ADV
easat-264	11	9	written	write	VERB
easat-264	11	10	by	by	ADP
easat-264	11	11	dg	dg	PROPN
easat-264	11	12	limbaugh	limbaugh	PROPN
easat-264	11	13	that	that	SCONJ
easat-264	11	14	“	"	PUNCT
easat-264	11	15	one	one	PRON
easat-264	11	16	can	can	AUX
easat-264	11	17	conceive	conceive	VERB
easat-264	11	18	of	of	ADP
easat-264	11	19	cases	case	NOUN
easat-264	11	20	where	where	SCONJ
easat-264	11	21	simultaneous	simultaneous	ADJ
easat-264	11	22	disorders	disorder	NOUN
easat-264	11	23	prevent	prevent	VERB
easat-264	11	24	each	each	DET
easat-264	11	25	other	other	ADJ
easat-264	11	26	from	from	ADP
easat-264	11	27	being	be	AUX
easat-264	11	28	,	,	PUNCT
easat-264	11	29	in	in	ADP
easat-264	11	30	any	any	DET
easat-264	11	31	traditional	traditional	ADJ
easat-264	11	32	sense	sense	NOUN
easat-264	11	33	,	,	PUNCT
easat-264	11	34	actually	actually	ADV
easat-264	11	35	harmful	harmful	ADJ
easat-264	11	36	”	"	PUNCT
easat-264	12	1	[	[	X
easat-264	12	2	1	1	NUM
easat-264	12	3	]	]	PUNCT
easat-264	12	4	.	.	PUNCT
easat-264	13	1	on	on	ADP
easat-264	13	2	even	even	ADV
easat-264	13	3	broader	broad	ADJ
easat-264	13	4	bases	basis	NOUN
easat-264	13	5	,	,	PUNCT
easat-264	13	6	the	the	DET
easat-264	13	7	concept	concept	NOUN
easat-264	13	8	of	of	ADP
easat-264	13	9	"	"	PUNCT
easat-264	13	10	one	one	NUM
easat-264	13	11	health	health	NOUN
easat-264	13	12	"	"	PUNCT
easat-264	13	13	has	have	AUX
easat-264	13	14	developed	develop	VERB
easat-264	13	15	in	in	ADP
easat-264	13	16	recent	recent	ADJ
easat-264	13	17	years	year	NOUN
easat-264	13	18	,	,	PUNCT
easat-264	13	19	which	which	PRON
easat-264	13	20	requires	require	VERB
easat-264	13	21	breaking	break	VERB
easat-264	13	22	down	down	ADP
easat-264	13	23	the	the	DET
easat-264	13	24	interdisciplinary	interdisciplinary	ADJ
easat-264	13	25	barriers	barrier	NOUN
easat-264	13	26	that	that	PRON
easat-264	13	27	still	still	ADV
easat-264	13	28	separate	separate	VERB
easat-264	13	29	human	human	ADJ
easat-264	13	30	and	and	CCONJ
easat-264	13	31	veterinary	veterinary	ADJ
easat-264	13	32	medicine	medicine	NOUN
easat-264	13	33	from	from	ADP
easat-264	13	34	ecological	ecological	ADJ
easat-264	13	35	,	,	PUNCT
easat-264	13	36	evolutionary	evolutionary	ADJ
easat-264	13	37	,	,	PUNCT
easat-264	13	38	and	and	CCONJ
easat-264	13	39	environmental	environmental	ADJ
easat-264	13	40	sciences	science	NOUN
easat-264	13	41	[	[	X
easat-264	13	42	2	2	NUM
easat-264	13	43	]	]	PUNCT
easat-264	13	44	.	.	PUNCT
easat-264	14	1	on	on	ADP
easat-264	14	2	the	the	DET
easat-264	14	3	same	same	ADJ
easat-264	14	4	way	way	NOUN
easat-264	14	5	appeared	appear	VERB
easat-264	14	6	the	the	DET
easat-264	14	7	concepts	concept	NOUN
easat-264	14	8	of	of	ADP
easat-264	14	9	personalized	personalized	ADJ
easat-264	14	10	medicine	medicine	NOUN
easat-264	14	11	,	,	PUNCT
easat-264	14	12	precision	precision	NOUN
easat-264	14	13	medicine	medicine	NOUN
easat-264	14	14	,	,	PUNCT
easat-264	14	15	integrative	integrative	ADJ
easat-264	14	16	medicine	medicine	NOUN
easat-264	14	17	or	or	CCONJ
easat-264	14	18	p4	p4	ADJ
easat-264	14	19	medicine	medicine	NOUN
easat-264	14	20	,	,	PUNCT
easat-264	14	21	all	all	PRON
easat-264	14	22	interconnected	interconnect	VERB
easat-264	14	23	by	by	ADP
easat-264	14	24	the	the	DET
easat-264	14	25	concept	concept	NOUN
easat-264	14	26	of	of	ADP
easat-264	14	27	globality	globality	NOUN
easat-264	14	28	and	and	CCONJ
easat-264	14	29	interactivity	interactivity	NOUN
easat-264	14	30	and	and	CCONJ
easat-264	14	31	using	use	VERB
easat-264	14	32	increasingly	increasingly	ADV
easat-264	14	33	powerful	powerful	ADJ
easat-264	14	34	tools	tool	NOUN
easat-264	14	35	.	.	PUNCT
easat-264	15	1	it	it	PRON
easat-264	15	2	should	should	AUX
easat-264	15	3	be	be	AUX
easat-264	15	4	noted	note	VERB
easat-264	15	5	at	at	ADP
easat-264	15	6	the	the	DET
easat-264	15	7	outset	outset	NOUN
easat-264	15	8	that	that	SCONJ
easat-264	15	9	all	all	DET
easat-264	15	10	these	these	DET
easat-264	15	11	concepts	concept	NOUN
easat-264	15	12	,	,	PUNCT
easat-264	15	13	which	which	PRON
easat-264	15	14	are	be	AUX
easat-264	15	15	relatively	relatively	ADV
easat-264	15	16	close	close	ADJ
easat-264	15	17	to	to	ADP
easat-264	15	18	the	the	DET
easat-264	15	19	others	other	NOUN
easat-264	15	20	,	,	PUNCT
easat-264	15	21	share	share	VERB
easat-264	15	22	the	the	DET
easat-264	15	23	same	same	ADJ
easat-264	15	24	concern	concern	NOUN
easat-264	15	25	,	,	PUNCT
easat-264	15	26	which	which	PRON
easat-264	15	27	is	be	AUX
easat-264	15	28	to	to	PART
easat-264	15	29	take	take	VERB
easat-264	15	30	on	on	ADP
easat-264	15	31	as	as	ADV
easat-264	15	32	effectively	effectively	ADV
easat-264	15	33	as	as	ADP
easat-264	15	34	possible	possible	ADJ
easat-264	15	35	the	the	DET
easat-264	15	36	major	major	ADJ
easat-264	15	37	challenge	challenge	NOUN
easat-264	15	38	represented	represent	VERB
easat-264	15	39	by	by	ADP
easat-264	15	40	the	the	DET
easat-264	15	41	exponential	exponential	ADJ
easat-264	15	42	development	development	NOUN
easat-264	15	43	of	of	ADP
easat-264	15	44	chronic	chronic	ADJ
easat-264	15	45	diseases	disease	NOUN
easat-264	15	46	throughout	throughout	ADP
easat-264	15	47	the	the	DET
easat-264	15	48	world	world	NOUN
easat-264	15	49	.	.	PUNCT
easat-264	16	1	in	in	ADP
easat-264	16	2	2011	2011	NUM
easat-264	16	3	,	,	PUNCT
easat-264	16	4	we	we	PRON
easat-264	16	5	could	could	AUX
easat-264	16	6	find	find	VERB
easat-264	16	7	following	follow	VERB
easat-264	16	8	definition	definition	NOUN
easat-264	16	9	of	of	ADP
easat-264	16	10	personalized	personalized	ADJ
easat-264	16	11	medicine	medicine	NOUN
easat-264	16	12	in	in	ADP
easat-264	16	13	u.s	u.s	PROPN
easat-264	16	14	.	.	PROPN
easat-264	16	15	news	news	PROPN
easat-264	16	16	:	:	PUNCT
easat-264	16	17	“	"	PUNCT
easat-264	16	18	personalized	personalized	ADJ
easat-264	16	19	medicine	medicine	NOUN
easat-264	16	20	is	be	AUX
easat-264	16	21	a	a	DET
easat-264	16	22	young	young	ADJ
easat-264	16	23	but	but	CCONJ
easat-264	16	24	rapidly	rapidly	ADV
easat-264	16	25	advancing	advance	VERB
easat-264	16	26	field	field	NOUN
easat-264	16	27	of	of	ADP
easat-264	16	28	healthcare	healthcare	NOUN
easat-264	16	29	that	that	PRON
easat-264	16	30	is	be	AUX
easat-264	16	31	informed	inform	VERB
easat-264	16	32	by	by	ADP
easat-264	16	33	each	each	DET
easat-264	16	34	person	person	NOUN
easat-264	16	35	's	's	PART
easat-264	16	36	unique	unique	ADJ
easat-264	16	37	clinical	clinical	ADJ
easat-264	16	38	,	,	PUNCT
easat-264	16	39	genetic	genetic	ADJ
easat-264	16	40	,	,	PUNCT
easat-264	16	41	genomic	genomic	NOUN
easat-264	16	42	,	,	PUNCT
easat-264	16	43	and	and	CCONJ
easat-264	16	44	environmental	environmental	ADJ
easat-264	16	45	information	information	NOUN
easat-264	16	46	.	.	PUNCT
easat-264	16	47	”	"	PUNCT
easat-264	17	1	because	because	SCONJ
easat-264	17	2	these	these	DET
easat-264	17	3	factors	factor	NOUN
easat-264	17	4	are	be	AUX
easat-264	17	5	different	different	ADJ
easat-264	17	6	for	for	ADP
easat-264	17	7	every	every	DET
easat-264	17	8	person	person	NOUN
easat-264	17	9	,	,	PUNCT
easat-264	17	10	“	"	PUNCT
easat-264	17	11	the	the	DET
easat-264	17	12	nature	nature	NOUN
easat-264	17	13	of	of	ADP
easat-264	17	14	diseases	disease	NOUN
easat-264	17	15	—	—	PUNCT
easat-264	17	16	including	include	VERB
easat-264	17	17	their	their	PRON
easat-264	17	18	onset	onset	NOUN
easat-264	17	19	,	,	PUNCT
easat-264	17	20	their	their	PRON
easat-264	17	21	course	course	NOUN
easat-264	17	22	,	,	PUNCT
easat-264	17	23	and	and	CCONJ
easat-264	17	24	how	how	SCONJ
easat-264	17	25	they	they	PRON
easat-264	17	26	might	might	AUX
easat-264	17	27	respond	respond	VERB
easat-264	17	28	to	to	ADP
easat-264	17	29	drugs	drug	NOUN
easat-264	17	30	or	or	CCONJ
easat-264	17	31	other	other	ADJ
easat-264	17	32	interventions	intervention	NOUN
easat-264	17	33	—	—	PUNCT
easat-264	17	34	is	be	AUX
easat-264	17	35	as	as	ADV
easat-264	17	36	individual	individual	ADJ
easat-264	17	37	as	as	ADP
easat-264	17	38	the	the	DET
easat-264	17	39	people	people	NOUN
easat-264	17	40	who	who	PRON
easat-264	17	41	have	have	VERB
easat-264	17	42	them	they	PRON
easat-264	17	43	(	(	PUNCT
easat-264	17	44	figure	figure	NOUN
easat-264	17	45	1	1	NUM
easat-264	17	46	)	)	PUNCT
easat-264	17	47	.	.	PUNCT
easat-264	17	48	”	"	PUNCT
easat-264	17	49	figure	figure	NOUN
easat-264	17	50	1	1	NUM
easat-264	17	51	.	.	PUNCT
easat-264	18	1	key	key	ADJ
easat-264	18	2	factors	factor	NOUN
easat-264	18	3	involved	involve	VERB
easat-264	18	4	in	in	ADP
easat-264	18	5	the	the	DET
easat-264	18	6	regulation	regulation	NOUN
easat-264	18	7	of	of	ADP
easat-264	18	8	energy	energy	NOUN
easat-264	18	9	balance	balance	NOUN
easat-264	18	10	.	.	PUNCT
easat-264	19	1	personalized	personalized	ADJ
easat-264	19	2	medicine	medicine	NOUN
easat-264	19	3	is	be	AUX
easat-264	19	4	about	about	ADP
easat-264	19	5	making	make	VERB
easat-264	19	6	the	the	DET
easat-264	19	7	treatment	treatment	NOUN
easat-264	19	8	as	as	ADV
easat-264	19	9	individualized	individualized	ADJ
easat-264	19	10	as	as	ADP
easat-264	19	11	the	the	DET
easat-264	19	12	disease	disease	NOUN
easat-264	19	13	.	.	PUNCT
easat-264	20	1	it	it	PRON
easat-264	20	2	involves	involve	VERB
easat-264	20	3	identifying	identify	VERB
easat-264	20	4	genetic	genetic	ADJ
easat-264	20	5	,	,	PUNCT
easat-264	20	6	genomic	genomic	NOUN
easat-264	20	7	,	,	PUNCT
easat-264	20	8	and	and	CCONJ
easat-264	20	9	clinical	clinical	ADJ
easat-264	20	10	information	information	NOUN
easat-264	20	11	that	that	PRON
easat-264	20	12	allows	allow	VERB
easat-264	20	13	accurate	accurate	ADJ
easat-264	20	14	predictions	prediction	NOUN
easat-264	20	15	to	to	PART
easat-264	20	16	be	be	AUX
easat-264	20	17	made	make	VERB
easat-264	20	18	about	about	ADP
easat-264	20	19	a	a	DET
easat-264	20	20	person	person	NOUN
easat-264	20	21	's	's	PART
easat-264	20	22	susceptibility	susceptibility	NOUN
easat-264	20	23	of	of	ADP
easat-264	20	24	developing	develop	VERB
easat-264	20	25	disease	disease	NOUN
easat-264	20	26	,	,	PUNCT
easat-264	20	27	the	the	DET
easat-264	20	28	course	course	NOUN
easat-264	20	29	of	of	ADP
easat-264	20	30	disease	disease	NOUN
easat-264	20	31	,	,	PUNCT
easat-264	20	32	and	and	CCONJ
easat-264	20	33	its	its	PRON
easat-264	20	34	response	response	NOUN
easat-264	20	35	to	to	ADP
easat-264	20	36	treatment	treatment	NOUN
easat-264	20	37	[	[	X
easat-264	20	38	3	3	NUM
easat-264	20	39	-	-	SYM
easat-264	20	40	5	5	NUM
easat-264	20	41	]	]	PUNCT
easat-264	20	42	(	(	PUNCT
easat-264	20	43	figure	figure	NOUN
easat-264	20	44	2	2	NUM
easat-264	20	45	)	)	PUNCT
easat-264	20	46	.	.	PUNCT
easat-264	21	1	figure	figure	NOUN
easat-264	21	2	2	2	NUM
easat-264	21	3	.	.	PUNCT
easat-264	21	4	frost	frost	NOUN
easat-264	21	5	and	and	CCONJ
easat-264	21	6	sullivan	sullivan	PROPN
easat-264	21	7	:	:	PUNCT
easat-264	21	8	new	new	ADJ
easat-264	21	9	paradigm	paradigm	NOUN
easat-264	21	10	shift	shift	NOUN
easat-264	21	11	in	in	ADP
easat-264	21	12	treatment	treatment	NOUN
easat-264	21	13	.	.	PUNCT
easat-264	22	1	in	in	ADP
easat-264	22	2	order	order	NOUN
easat-264	22	3	for	for	ADP
easat-264	22	4	personalized	personalized	ADJ
easat-264	22	5	medicine	medicine	NOUN
easat-264	22	6	to	to	PART
easat-264	22	7	be	be	AUX
easat-264	22	8	used	use	VERB
easat-264	22	9	effectively	effectively	ADV
easat-264	22	10	by	by	ADP
easat-264	22	11	healthcare	healthcare	NOUN
easat-264	22	12	providers	provider	NOUN
easat-264	22	13	and	and	CCONJ
easat-264	22	14	their	their	PRON
easat-264	22	15	patients	patient	NOUN
easat-264	22	16	,	,	PUNCT
easat-264	22	17	these	these	DET
easat-264	22	18	findings	finding	NOUN
easat-264	22	19	must	must	AUX
easat-264	22	20	be	be	AUX
easat-264	22	21	translated	translate	VERB
easat-264	22	22	into	into	ADP
easat-264	22	23	precise	precise	ADJ
easat-264	22	24	diagnostic	diagnostic	ADJ
easat-264	22	25	tests	test	NOUN
easat-264	22	26	and	and	CCONJ
easat-264	22	27	targeted	target	VERB
easat-264	22	28	therapies	therapy	NOUN
easat-264	22	29	(	(	PUNCT
easat-264	22	30	figure	figure	NOUN
easat-264	22	31	3	3	NUM
easat-264	22	32	)	)	PUNCT
easat-264	22	33	.	.	PUNCT
easat-264	23	1	specific	specific	ADJ
easat-264	23	2	advantages	advantage	NOUN
easat-264	23	3	that	that	PRON
easat-264	23	4	personalized	personalized	ADJ
easat-264	23	5	medicine	medicine	NOUN
easat-264	23	6	may	may	AUX
easat-264	23	7	offer	offer	VERB
easat-264	23	8	patients	patient	NOUN
easat-264	23	9	and	and	CCONJ
easat-264	23	10	clinicians	clinician	NOUN
easat-264	23	11	include	include	VERB
easat-264	23	12	:	:	PUNCT
easat-264	23	13	•	•	NOUN
easat-264	23	14	ability	ability	NOUN
easat-264	23	15	to	to	PART
easat-264	23	16	make	make	VERB
easat-264	23	17	more	more	ADV
easat-264	23	18	informed	informed	ADJ
easat-264	23	19	medical	medical	ADJ
easat-264	23	20	decisions	decision	NOUN
easat-264	23	21	•	•	ADP
easat-264	23	22	higher	high	ADJ
easat-264	23	23	probability	probability	NOUN
easat-264	23	24	of	of	ADP
easat-264	23	25	desired	desire	VERB
easat-264	23	26	outcomes	outcome	NOUN
easat-264	23	27	thanks	thank	NOUN
easat-264	23	28	to	to	ADP
easat-264	23	29	better	well	ADV
easat-264	23	30	-	-	PUNCT
easat-264	23	31	targeted	target	VERB
easat-264	23	32	therapies	therapy	NOUN
easat-264	23	33	•	•	ADV
easat-264	23	34	reduced	reduce	VERB
easat-264	23	35	healthcare	healthcare	NOUN
easat-264	23	36	costs	cost	NOUN
easat-264	23	37	•	•	VERB
easat-264	23	38	reduced	reduce	VERB
easat-264	23	39	probability	probability	NOUN
easat-264	23	40	of	of	ADP
easat-264	23	41	negative	negative	ADJ
easat-264	23	42	side	side	NOUN
easat-264	23	43	effects	effect	NOUN
easat-264	23	44	•	•	NOUN
easat-264	23	45	focus	focus	NOUN
easat-264	23	46	on	on	ADP
easat-264	23	47	prevention	prevention	NOUN
easat-264	23	48	and	and	CCONJ
easat-264	23	49	prediction	prediction	NOUN
easat-264	23	50	of	of	ADP
easat-264	23	51	disease	disease	NOUN
easat-264	23	52	rather	rather	ADV
easat-264	23	53	than	than	ADP
easat-264	23	54	reaction	reaction	NOUN
easat-264	23	55	to	to	ADP
easat-264	23	56	it	it	PRON
easat-264	23	57	•	•	NOUN
easat-264	23	58	earlier	early	ADJ
easat-264	23	59	disease	disease	NOUN
easat-264	23	60	intervention	intervention	NOUN
easat-264	23	61	than	than	ADP
easat-264	23	62	what	what	PRON
easat-264	23	63	has	have	AUX
easat-264	23	64	been	be	AUX
easat-264	23	65	possible	possible	ADJ
easat-264	23	66	in	in	ADP
easat-264	23	67	the	the	DET
easat-264	23	68	past	past	ADJ
easat-264	23	69	mailto:info@ebma-europe.com	mailto:info@ebma-europe.com	PROPN
easat-264	23	70	27	27	NUM
easat-264	23	71	edelweiss	edelweiss	PROPN
easat-264	23	72	applied	apply	VERB
easat-264	23	73	science	science	NOUN
easat-264	23	74	and	and	CCONJ
easat-264	23	75	technology	technology	NOUN
easat-264	23	76	issn	issn	PROPN
easat-264	23	77	:	:	PUNCT
easat-264	23	78	2576	2576	NUM
easat-264	23	79	-	-	SYM
easat-264	23	80	8484	8484	NUM
easat-264	23	81	vol	vol	NOUN
easat-264	23	82	.	.	PROPN
easat-264	24	1	3	3	NUM
easat-264	24	2	,	,	PUNCT
easat-264	24	3	no	no	INTJ
easat-264	24	4	.	.	NOUN
easat-264	24	5	1	1	NUM
easat-264	24	6	:	:	SYM
easat-264	24	7	26	26	NUM
easat-264	24	8	-	-	SYM
easat-264	24	9	29	29	NUM
easat-264	24	10	,	,	PUNCT
easat-264	24	11	2019	2019	NUM
easat-264	24	12	doi	doi	NOUN
easat-264	24	13	:	:	PUNCT
easat-264	24	14	10.33805/2576	10.33805/2576	NUM
easat-264	24	15	-	-	SYM
easat-264	24	16	8484.164	8484.164	NUM
easat-264	24	17	©	©	ADP
easat-264	24	18	2019	2019	NUM
easat-264	24	19	by	by	ADP
easat-264	24	20	the	the	DET
easat-264	24	21	author	author	NOUN
easat-264	24	22	figure	figure	NOUN
easat-264	24	23	3	3	NUM
easat-264	24	24	.	.	PUNCT
easat-264	24	25	personalized	personalize	VERB
easat-264	24	26	medicine	medicine	NOUN
easat-264	24	27	and	and	CCONJ
easat-264	24	28	treatment	treatment	NOUN
easat-264	24	29	,	,	PUNCT
easat-264	24	30	nhs	nhs	PROPN
easat-264	24	31	explanation	explanation	NOUN
easat-264	24	32	document	document	NOUN
easat-264	24	33	.	.	PUNCT
easat-264	25	1	the	the	DET
easat-264	25	2	four	four	NUM
easat-264	25	3	‘	'	PUNCT
easat-264	25	4	p	p	X
easat-264	25	5	’s	’s	NOUN
easat-264	25	6	of	of	ADP
easat-264	25	7	personalized	personalized	ADJ
easat-264	25	8	medicine	medicine	NOUN
easat-264	25	9	have	have	AUX
easat-264	25	10	thus	thus	ADV
easat-264	25	11	given	give	VERB
easat-264	25	12	birth	birth	NOUN
easat-264	25	13	to	to	ADP
easat-264	25	14	p4	p4	ADJ
easat-264	25	15	medicine	medicine	NOUN
easat-264	25	16	,	,	PUNCT
easat-264	25	17	a	a	DET
easat-264	25	18	term	term	NOUN
easat-264	25	19	coined	coin	VERB
easat-264	25	20	by	by	ADP
easat-264	25	21	david	david	PROPN
easat-264	25	22	galas	galas	PROPN
easat-264	25	23	and	and	CCONJ
easat-264	25	24	leroy	leroy	PROPN
easat-264	25	25	hood	hood	PROPN
easat-264	25	26	from	from	ADP
easat-264	25	27	the	the	DET
easat-264	25	28	institute	institute	NOUN
easat-264	25	29	for	for	ADP
easat-264	25	30	systems	system	NOUN
easat-264	25	31	biology	biology	NOUN
easat-264	25	32	(	(	PUNCT
easat-264	25	33	isb	isb	NOUN
easat-264	25	34	)	)	PUNCT
easat-264	25	35	in	in	ADP
easat-264	25	36	seattle	seattle	PROPN
easat-264	25	37	,	,	PUNCT
easat-264	25	38	and	and	CCONJ
easat-264	25	39	based	base	VERB
easat-264	25	40	on	on	ADP
easat-264	25	41	four	four	NUM
easat-264	25	42	references	reference	NOUN
easat-264	25	43	:	:	PUNCT
easat-264	25	44	predictive	predictive	ADJ
easat-264	25	45	,	,	PUNCT
easat-264	25	46	preventive	preventive	ADJ
easat-264	25	47	,	,	PUNCT
easat-264	25	48	personalized	personalized	ADJ
easat-264	25	49	and	and	CCONJ
easat-264	25	50	participatory	participatory	ADJ
easat-264	25	51	[	[	X
easat-264	25	52	6,7	6,7	NUM
easat-264	25	53	]	]	PUNCT
easat-264	25	54	.	.	PUNCT
easat-264	26	1	the	the	DET
easat-264	26	2	conceptual	conceptual	ADJ
easat-264	26	3	matrix	matrix	NOUN
easat-264	26	4	at	at	ADP
easat-264	26	5	the	the	DET
easat-264	26	6	origin	origin	NOUN
easat-264	26	7	of	of	ADP
easat-264	26	8	all	all	DET
easat-264	26	9	these	these	DET
easat-264	26	10	evolutions	evolution	NOUN
easat-264	26	11	of	of	ADP
easat-264	26	12	medical	medical	ADJ
easat-264	26	13	thinking	thinking	NOUN
easat-264	26	14	remains	remain	VERB
easat-264	26	15	this	this	PRON
easat-264	26	16	of	of	ADP
easat-264	26	17	“	"	PUNCT
easat-264	26	18	systems	system	NOUN
easat-264	26	19	biology	biology	NOUN
easat-264	26	20	”	"	PUNCT
easat-264	26	21	with	with	ADP
easat-264	26	22	its	its	PRON
easat-264	26	23	central	central	ADJ
easat-264	26	24	components	component	NOUN
easat-264	26	25	that	that	PRON
easat-264	26	26	are	be	AUX
easat-264	26	27	genetically	genetically	ADV
easat-264	26	28	programmed	program	VERB
easat-264	26	29	networks	network	NOUN
easat-264	26	30	(	(	PUNCT
easat-264	26	31	circuits	circuit	NOUN
easat-264	26	32	)	)	PUNCT
easat-264	26	33	within	within	ADP
easat-264	26	34	cells	cell	NOUN
easat-264	26	35	and	and	CCONJ
easat-264	26	36	networks	network	NOUN
easat-264	26	37	of	of	ADP
easat-264	26	38	cells	cell	NOUN
easat-264	26	39	[	[	X
easat-264	26	40	8	8	NUM
easat-264	26	41	]	]	PUNCT
easat-264	26	42	.	.	PUNCT
easat-264	27	1	1.1	1.1	NUM
easat-264	27	2	.	.	PUNCT
easat-264	27	3	prediction	prediction	NOUN
easat-264	27	4	and	and	CCONJ
easat-264	27	5	prevention	prevention	NOUN
easat-264	27	6	of	of	ADP
easat-264	27	7	disease	disease	NOUN
easat-264	27	8	using	use	VERB
easat-264	27	9	genomic	genomic	NOUN
easat-264	27	10	technologies	technology	NOUN
easat-264	27	11	and	and	CCONJ
easat-264	27	12	other	other	ADJ
easat-264	27	13	diagnostics	diagnostic	NOUN
easat-264	27	14	,	,	PUNCT
easat-264	27	15	we	we	PRON
easat-264	27	16	will	will	AUX
easat-264	27	17	be	be	AUX
easat-264	27	18	able	able	ADJ
easat-264	27	19	to	to	PART
easat-264	27	20	identify	identify	VERB
easat-264	27	21	people	people	NOUN
easat-264	27	22	most	most	ADV
easat-264	27	23	at	at	ADP
easat-264	27	24	risk	risk	NOUN
easat-264	27	25	of	of	ADP
easat-264	27	26	disease	disease	NOUN
easat-264	27	27	even	even	ADV
easat-264	27	28	before	before	ADP
easat-264	27	29	the	the	DET
easat-264	27	30	onset	onset	NOUN
easat-264	27	31	of	of	ADP
easat-264	27	32	their	their	PRON
easat-264	27	33	symptoms	symptom	NOUN
easat-264	27	34	.	.	PUNCT
easat-264	28	1	earlier	early	ADJ
easat-264	28	2	detection	detection	NOUN
easat-264	28	3	will	will	AUX
easat-264	28	4	open	open	VERB
easat-264	28	5	up	up	ADP
easat-264	28	6	the	the	DET
easat-264	28	7	prospect	prospect	NOUN
easat-264	28	8	of	of	ADP
easat-264	28	9	new	new	ADJ
easat-264	28	10	treatment	treatment	NOUN
easat-264	28	11	options	option	NOUN
easat-264	28	12	and	and	CCONJ
easat-264	28	13	support	support	VERB
easat-264	28	14	people	people	NOUN
easat-264	28	15	to	to	PART
easat-264	28	16	make	make	VERB
easat-264	28	17	informed	informed	ADJ
easat-264	28	18	lifestyle	lifestyle	NOUN
easat-264	28	19	choices	choice	NOUN
easat-264	28	20	.	.	PUNCT
easat-264	29	1	more	more	ADV
easat-264	29	2	precise	precise	ADJ
easat-264	29	3	diagnoses	diagnose	VERB
easat-264	29	4	thanks	thank	NOUN
easat-264	29	5	to	to	ADP
easat-264	29	6	the	the	DET
easat-264	29	7	knowledge	knowledge	NOUN
easat-264	29	8	of	of	ADP
easat-264	29	9	each	each	DET
easat-264	29	10	individual	individual	NOUN
easat-264	29	11	’s	’s	PART
easat-264	29	12	complex	complex	ADJ
easat-264	29	13	molecular	molecular	ADJ
easat-264	29	14	and	and	CCONJ
easat-264	29	15	cellular	cellular	ADJ
easat-264	29	16	processes	process	NOUN
easat-264	29	17	,	,	PUNCT
easat-264	29	18	informed	inform	VERB
easat-264	29	19	by	by	ADP
easat-264	29	20	other	other	ADJ
easat-264	29	21	clinical	clinical	ADJ
easat-264	29	22	and	and	CCONJ
easat-264	29	23	diagnostic	diagnostic	ADJ
easat-264	29	24	information	information	NOUN
easat-264	29	25	define	define	VERB
easat-264	29	26	the	the	DET
easat-264	29	27	so	so	ADV
easat-264	29	28	-	-	PUNCT
easat-264	29	29	called	call	VERB
easat-264	29	30	precision	precision	NOUN
easat-264	29	31	medicine	medicine	NOUN
easat-264	29	32	[	[	X
easat-264	29	33	9	9	NUM
easat-264	29	34	]	]	PUNCT
easat-264	29	35	(	(	PUNCT
easat-264	29	36	figure	figure	NOUN
easat-264	29	37	4	4	NUM
easat-264	29	38	)	)	PUNCT
easat-264	29	39	.	.	PUNCT
easat-264	30	1	figure	figure	VERB
easat-264	30	2	4	4	NUM
easat-264	30	3	.	.	PUNCT
easat-264	30	4	personalized	personalized	ADJ
easat-264	30	5	and	and	CCONJ
easat-264	30	6	precision	precision	NOUN
easat-264	30	7	medicine	medicine	NOUN
easat-264	30	8	.	.	PUNCT
easat-264	31	1	1.2	1.2	NUM
easat-264	31	2	.	.	NUM
easat-264	31	3	targeted	target	VERB
easat-264	31	4	and	and	CCONJ
easat-264	31	5	personalized	personalized	ADJ
easat-264	31	6	interventions	intervention	NOUN
easat-264	31	7	we	we	PRON
easat-264	31	8	are	be	AUX
easat-264	31	9	already	already	ADV
easat-264	31	10	beginning	begin	VERB
easat-264	31	11	to	to	PART
easat-264	31	12	see	see	VERB
easat-264	31	13	the	the	DET
easat-264	31	14	development	development	NOUN
easat-264	31	15	of	of	ADP
easat-264	31	16	simple	simple	ADJ
easat-264	31	17	point	point	NOUN
easat-264	31	18	of	of	ADP
easat-264	31	19	care	care	NOUN
easat-264	31	20	tests	test	NOUN
easat-264	31	21	,	,	PUNCT
easat-264	31	22	based	base	VERB
easat-264	31	23	on	on	ADP
easat-264	31	24	genomic	genomic	ADJ
easat-264	31	25	knowledge	knowledge	NOUN
easat-264	31	26	,	,	PUNCT
easat-264	31	27	which	which	PRON
easat-264	31	28	enable	enable	VERB
easat-264	31	29	clinicians	clinician	NOUN
easat-264	31	30	in	in	ADP
easat-264	31	31	a	a	DET
easat-264	31	32	wide	wide	ADJ
easat-264	31	33	variety	variety	NOUN
easat-264	31	34	of	of	ADP
easat-264	31	35	settings	setting	NOUN
easat-264	31	36	to	to	PART
easat-264	31	37	identify	identify	VERB
easat-264	31	38	the	the	DET
easat-264	31	39	best	good	ADJ
easat-264	31	40	therapy	therapy	NOUN
easat-264	31	41	.	.	PUNCT
easat-264	32	1	variants	variant	NOUN
easat-264	32	2	in	in	ADP
easat-264	32	3	our	our	PRON
easat-264	32	4	genetic	genetic	ADJ
easat-264	32	5	code	code	NOUN
easat-264	32	6	can	can	AUX
easat-264	32	7	also	also	ADV
easat-264	32	8	be	be	AUX
easat-264	32	9	used	use	VERB
easat-264	32	10	to	to	PART
easat-264	32	11	predict	predict	VERB
easat-264	32	12	the	the	DET
easat-264	32	13	potential	potential	NOUN
easat-264	32	14	for	for	ADP
easat-264	32	15	adverse	adverse	ADJ
easat-264	32	16	drug	drug	NOUN
easat-264	32	17	reactions	reaction	NOUN
easat-264	32	18	[	[	X
easat-264	32	19	10	10	NUM
easat-264	32	20	]	]	PUNCT
easat-264	32	21	.	.	PUNCT
easat-264	33	1	the	the	DET
easat-264	33	2	ability	ability	NOUN
easat-264	33	3	for	for	ADP
easat-264	33	4	a	a	DET
easat-264	33	5	clinician	clinician	NOUN
easat-264	33	6	to	to	PART
easat-264	33	7	discuss	discuss	VERB
easat-264	33	8	with	with	ADP
easat-264	33	9	their	their	PRON
easat-264	33	10	patients	patient	NOUN
easat-264	33	11	about	about	ADP
easat-264	33	12	information	information	NOUN
easat-264	33	13	on	on	ADP
easat-264	33	14	individual	individual	ADJ
easat-264	33	15	genomic	genomic	NOUN
easat-264	33	16	characteristics	characteristic	NOUN
easat-264	33	17	,	,	PUNCT
easat-264	33	18	lifestyle	lifestyle	NOUN
easat-264	33	19	and	and	CCONJ
easat-264	33	20	environmental	environmental	ADJ
easat-264	33	21	factors	factor	NOUN
easat-264	33	22	,	,	PUNCT
easat-264	33	23	and	and	CCONJ
easat-264	33	24	interpret	interpret	VERB
easat-264	33	25	personal	personal	ADJ
easat-264	33	26	data	datum	NOUN
easat-264	33	27	from	from	ADP
easat-264	33	28	wearable	wearable	ADJ
easat-264	33	29	technology	technology	NOUN
easat-264	33	30	will	will	AUX
easat-264	33	31	drive	drive	VERB
easat-264	33	32	a	a	DET
easat-264	33	33	new	new	ADJ
easat-264	33	34	type	type	NOUN
easat-264	33	35	of	of	ADP
easat-264	33	36	conversation	conversation	NOUN
easat-264	33	37	,	,	PUNCT
easat-264	33	38	that	that	PRON
easat-264	33	39	might	might	AUX
easat-264	33	40	lead	lead	VERB
easat-264	33	41	patients	patient	NOUN
easat-264	33	42	to	to	PART
easat-264	33	43	consider	consider	VERB
easat-264	33	44	preventive	preventive	ADJ
easat-264	33	45	measures	measure	NOUN
easat-264	33	46	with	with	ADP
easat-264	33	47	the	the	DET
easat-264	33	48	idea	idea	NOUN
easat-264	33	49	that	that	SCONJ
easat-264	33	50	patients	patient	NOUN
easat-264	33	51	should	should	AUX
easat-264	33	52	play	play	VERB
easat-264	33	53	a	a	DET
easat-264	33	54	decisive	decisive	ADJ
easat-264	33	55	role	role	NOUN
easat-264	33	56	in	in	ADP
easat-264	33	57	their	their	PRON
easat-264	33	58	own	own	ADJ
easat-264	33	59	healthcare	healthcare	NOUN
easat-264	33	60	by	by	ADP
easat-264	33	61	actively	actively	ADV
easat-264	33	62	controlling	control	VERB
easat-264	33	63	their	their	PRON
easat-264	33	64	health	health	NOUN
easat-264	33	65	status	status	NOUN
easat-264	33	66	and	and	CCONJ
easat-264	33	67	participating	participate	VERB
easat-264	33	68	in	in	ADP
easat-264	33	69	the	the	DET
easat-264	33	70	decisionmaking	decisionmake	VERB
easat-264	33	71	process	process	NOUN
easat-264	33	72	regarding	regard	VERB
easat-264	33	73	their	their	PRON
easat-264	33	74	treatments	treatment	NOUN
easat-264	33	75	[	[	X
easat-264	33	76	11	11	NUM
easat-264	33	77	]	]	SYM
easat-264	33	78	.	.	PUNCT
easat-264	34	1	2	2	X
easat-264	34	2	.	.	X
easat-264	34	3	material	material	NOUN
easat-264	34	4	and	and	CCONJ
easat-264	34	5	methods	method	NOUN
easat-264	34	6	the	the	DET
easat-264	34	7	bio	bio	NOUN
easat-264	34	8	immune(g)ene	immune(g)ene	ADJ
easat-264	34	9	medicine	medicine	NOUN
easat-264	34	10	,	,	PUNCT
easat-264	34	11	so	so	ADV
easat-264	34	12	-	-	PUNCT
easat-264	34	13	called	call	VERB
easat-264	34	14	bi(g)med	bi(g)me	VERB
easat-264	34	15	,	,	PUNCT
easat-264	34	16	is	be	AUX
easat-264	34	17	first	first	ADJ
easat-264	34	18	and	and	CCONJ
easat-264	34	19	foremost	foremost	ADV
easat-264	34	20	a	a	DET
easat-264	34	21	method	method	NOUN
easat-264	34	22	combining	combine	VERB
easat-264	34	23	predictive	predictive	ADJ
easat-264	34	24	diagnosis	diagnosis	NOUN
easat-264	34	25	as	as	ADV
easat-264	34	26	well	well	ADV
easat-264	34	27	as	as	ADP
easat-264	34	28	biomimetic	biomimetic	ADJ
easat-264	34	29	and	and	CCONJ
easat-264	34	30	personalized	personalized	ADJ
easat-264	34	31	treatment	treatment	NOUN
easat-264	34	32	(	(	PUNCT
easat-264	34	33	figure	figure	NOUN
easat-264	34	34	5	5	NUM
easat-264	34	35	)	)	PUNCT
easat-264	34	36	.	.	PUNCT
easat-264	35	1	to	to	PART
easat-264	35	2	try	try	VERB
easat-264	35	3	to	to	PART
easat-264	35	4	achieve	achieve	VERB
easat-264	35	5	this	this	DET
easat-264	35	6	objective	objective	NOUN
easat-264	35	7	,	,	PUNCT
easat-264	35	8	there	there	PRON
easat-264	35	9	is	be	VERB
easat-264	35	10	currently	currently	ADV
easat-264	35	11	a	a	DET
easat-264	35	12	very	very	ADV
easat-264	35	13	fruitful	fruitful	ADJ
easat-264	35	14	concept	concept	NOUN
easat-264	35	15	,	,	PUNCT
easat-264	35	16	that	that	PRON
easat-264	35	17	of	of	ADP
easat-264	35	18	"	"	PUNCT
easat-264	35	19	systems	system	NOUN
easat-264	35	20	biology	biology	NOUN
easat-264	35	21	"	"	PUNCT
easat-264	35	22	,	,	PUNCT
easat-264	35	23	aiming	aim	VERB
easat-264	35	24	at	at	ADP
easat-264	35	25	a	a	DET
easat-264	35	26	global	global	ADJ
easat-264	35	27	approach	approach	NOUN
easat-264	35	28	of	of	ADP
easat-264	35	29	biological	biological	ADJ
easat-264	35	30	phenomena	phenomenon	NOUN
easat-264	35	31	.	.	PUNCT
easat-264	36	1	figure	figure	VERB
easat-264	36	2	5	5	NUM
easat-264	36	3	.	.	PUNCT
easat-264	37	1	understanding	understand	VERB
easat-264	37	2	the	the	DET
easat-264	37	3	complex	complex	ADJ
easat-264	37	4	molecular	molecular	ADJ
easat-264	37	5	network	network	NOUN
easat-264	37	6	is	be	AUX
easat-264	37	7	the	the	DET
easat-264	37	8	center	center	NOUN
easat-264	37	9	of	of	ADP
easat-264	37	10	systems	system	NOUN
easat-264	37	11	biology	biology	NOUN
easat-264	37	12	and	and	CCONJ
easat-264	37	13	systems	system	NOUN
easat-264	37	14	medicine	medicine	NOUN
easat-264	37	15	[	[	X
easat-264	37	16	12	12	NUM
easat-264	37	17	]	]	PUNCT
easat-264	37	18	.	.	PUNCT
easat-264	38	1	systems	system	NOUN
easat-264	38	2	biology	biology	NOUN
easat-264	38	3	employs	employ	VERB
easat-264	38	4	a	a	DET
easat-264	38	5	holistic	holistic	ADJ
easat-264	38	6	approach	approach	NOUN
easat-264	38	7	to	to	PART
easat-264	38	8	study	study	VERB
easat-264	38	9	all	all	DET
easat-264	38	10	components	component	NOUN
easat-264	38	11	and	and	CCONJ
easat-264	38	12	interactions	interaction	NOUN
easat-264	38	13	in	in	ADP
easat-264	38	14	the	the	DET
easat-264	38	15	network	network	NOUN
easat-264	38	16	of	of	ADP
easat-264	38	17	dna	dna	PROPN
easat-264	38	18	(	(	PUNCT
easat-264	38	19	genes	gene	NOUN
easat-264	38	20	)	)	PUNCT
easat-264	38	21	,	,	PUNCT
easat-264	38	22	rna	rna	NOUN
easat-264	38	23	,	,	PUNCT
easat-264	38	24	proteins	protein	NOUN
easat-264	38	25	and	and	CCONJ
easat-264	38	26	biochemical	biochemical	ADJ
easat-264	38	27	reactions	reaction	NOUN
easat-264	38	28	within	within	ADP
easat-264	38	29	a	a	DET
easat-264	38	30	cell	cell	NOUN
easat-264	38	31	or	or	CCONJ
easat-264	38	32	an	an	DET
easat-264	38	33	organism	organism	NOUN
easat-264	38	34	.	.	PUNCT
easat-264	39	1	this	this	DET
easat-264	39	2	concept	concept	NOUN
easat-264	39	3	of	of	ADP
easat-264	39	4	"	"	PUNCT
easat-264	39	5	systems	system	NOUN
easat-264	39	6	biology	biology	NOUN
easat-264	39	7	"	"	PUNCT
easat-264	39	8	corresponds	correspond	VERB
easat-264	39	9	entirely	entirely	ADV
easat-264	39	10	to	to	ADP
easat-264	39	11	the	the	DET
easat-264	39	12	approach	approach	NOUN
easat-264	39	13	of	of	ADP
easat-264	39	14	human	human	ADJ
easat-264	39	15	diseases	disease	NOUN
easat-264	39	16	that	that	PRON
easat-264	39	17	we	we	PRON
easat-264	39	18	have	have	AUX
easat-264	39	19	been	be	AUX
easat-264	39	20	using	use	VERB
easat-264	39	21	for	for	ADP
easat-264	39	22	many	many	ADJ
easat-264	39	23	years	year	NOUN
easat-264	39	24	in	in	ADP
easat-264	39	25	the	the	DET
easat-264	39	26	framework	framework	NOUN
easat-264	39	27	of	of	ADP
easat-264	39	28	bi(g)med	bi(g)me	VERB
easat-264	39	29	,	,	PUNCT
easat-264	39	30	and	and	CCONJ
easat-264	39	31	that	that	SCONJ
easat-264	39	32	we	we	PRON
easat-264	39	33	are	be	AUX
easat-264	39	34	able	able	ADJ
easat-264	39	35	to	to	PART
easat-264	39	36	translate	translate	VERB
easat-264	39	37	at	at	ADP
easat-264	39	38	both	both	CCONJ
easat-264	39	39	the	the	DET
easat-264	39	40	diagnostic	diagnostic	ADJ
easat-264	39	41	and	and	CCONJ
easat-264	39	42	therapeutic	therapeutic	ADJ
easat-264	39	43	level	level	NOUN
easat-264	39	44	.	.	PUNCT
easat-264	40	1	at	at	ADP
easat-264	40	2	the	the	DET
easat-264	40	3	diagnostic	diagnostic	ADJ
easat-264	40	4	level	level	NOUN
easat-264	40	5	,	,	PUNCT
easat-264	40	6	we	we	PRON
easat-264	40	7	have	have	VERB
easat-264	40	8	a	a	DET
easat-264	40	9	very	very	ADV
easat-264	40	10	efficient	efficient	ADJ
easat-264	40	11	overview	overview	NOUN
easat-264	40	12	of	of	ADP
easat-264	40	13	the	the	DET
easat-264	40	14	cellular	cellular	ADJ
easat-264	40	15	immune	immune	ADJ
easat-264	40	16	system	system	NOUN
easat-264	40	17	thanks	thank	NOUN
easat-264	40	18	to	to	ADP
easat-264	40	19	the	the	DET
easat-264	40	20	lymphocyte	lymphocyte	ADJ
easat-264	40	21	phenotyping	phenotyping	NOUN
easat-264	40	22	,	,	PUNCT
easat-264	40	23	which	which	PRON
easat-264	40	24	is	be	AUX
easat-264	40	25	not	not	PART
easat-264	40	26	only	only	ADV
easat-264	40	27	an	an	DET
easat-264	40	28	important	important	ADJ
easat-264	40	29	tool	tool	NOUN
easat-264	40	30	for	for	ADP
easat-264	40	31	the	the	DET
easat-264	40	32	diagnosis	diagnosis	NOUN
easat-264	40	33	of	of	ADP
easat-264	40	34	hematological	hematological	ADJ
easat-264	40	35	and	and	CCONJ
easat-264	40	36	immunological	immunological	ADJ
easat-264	40	37	disorders	disorder	NOUN
easat-264	40	38	,	,	PUNCT
easat-264	40	39	but	but	CCONJ
easat-264	40	40	also	also	ADV
easat-264	40	41	a	a	DET
easat-264	40	42	means	means	NOUN
easat-264	40	43	of	of	ADP
easat-264	40	44	fine	fine	ADJ
easat-264	40	45	-	-	PUNCT
easat-264	40	46	tuning	tune	VERB
easat-264	40	47	cellular	cellular	ADJ
easat-264	40	48	immune	immune	ADJ
easat-264	40	49	status	status	NOUN
easat-264	40	50	and	and	CCONJ
easat-264	40	51	drawing	draw	VERB
easat-264	40	52	predictive	predictive	ADJ
easat-264	40	53	conclusions	conclusion	NOUN
easat-264	40	54	[	[	X
easat-264	40	55	12	12	NUM
easat-264	40	56	-	-	SYM
easat-264	40	57	14	14	NUM
easat-264	40	58	]	]	PUNCT
easat-264	40	59	(	(	PUNCT
easat-264	40	60	figure	figure	NOUN
easat-264	40	61	6	6	NUM
easat-264	40	62	)	)	PUNCT
easat-264	40	63	.	.	PUNCT
easat-264	41	1	figure	figure	VERB
easat-264	41	2	6	6	NUM
easat-264	41	3	.	.	NOUN
easat-264	41	4	example	example	NOUN
easat-264	41	5	of	of	ADP
easat-264	41	6	a	a	DET
easat-264	41	7	lymphocyte	lymphocyte	ADJ
easat-264	41	8	phenotyping	phenotyping	NOUN
easat-264	41	9	.	.	PUNCT
easat-264	42	1	to	to	PART
easat-264	42	2	appreciate	appreciate	VERB
easat-264	42	3	the	the	DET
easat-264	42	4	humoral	humoral	ADJ
easat-264	42	5	mediated	mediate	VERB
easat-264	42	6	immune	immune	ADJ
easat-264	42	7	system	system	NOUN
easat-264	42	8	,	,	PUNCT
easat-264	42	9	we	we	PRON
easat-264	42	10	use	use	VERB
easat-264	42	11	the	the	DET
easat-264	42	12	protein	protein	NOUN
easat-264	42	13	profile	profile	NOUN
easat-264	42	14	,	,	PUNCT
easat-264	42	15	which	which	PRON
easat-264	42	16	allows	allow	VERB
easat-264	42	17	us	we	PRON
easat-264	42	18	to	to	PART
easat-264	42	19	measure	measure	VERB
easat-264	42	20	several	several	ADJ
easat-264	42	21	types	type	NOUN
easat-264	42	22	of	of	ADP
easat-264	42	23	humoral	humoral	ADJ
easat-264	42	24	immune	immune	ADJ
easat-264	42	25	responses	response	NOUN
easat-264	42	26	that	that	PRON
easat-264	42	27	are	be	AUX
easat-264	42	28	both	both	CCONJ
easat-264	42	29	complementary	complementary	ADJ
easat-264	42	30	and	and	CCONJ
easat-264	42	31	interactive	interactive	ADJ
easat-264	42	32	[	[	X
easat-264	42	33	15	15	NUM
easat-264	42	34	]	]	X
easat-264	42	35	(	(	PUNCT
easat-264	42	36	figure	figure	NOUN
easat-264	42	37	7	7	NUM
easat-264	42	38	)	)	PUNCT
easat-264	42	39	.	.	PUNCT
easat-264	43	1	28	28	NUM
easat-264	43	2	edelweiss	edelweiss	PROPN
easat-264	43	3	applied	apply	VERB
easat-264	43	4	science	science	NOUN
easat-264	43	5	and	and	CCONJ
easat-264	43	6	technology	technology	NOUN
easat-264	43	7	issn	issn	PROPN
easat-264	43	8	:	:	PUNCT
easat-264	43	9	2576	2576	NUM
easat-264	43	10	-	-	SYM
easat-264	43	11	8484	8484	NUM
easat-264	43	12	vol	vol	NOUN
easat-264	43	13	.	.	PROPN
easat-264	44	1	3	3	NUM
easat-264	44	2	,	,	PUNCT
easat-264	44	3	no	no	INTJ
easat-264	44	4	.	.	NOUN
easat-264	44	5	1	1	NUM
easat-264	44	6	:	:	SYM
easat-264	44	7	26	26	NUM
easat-264	44	8	-	-	SYM
easat-264	44	9	29	29	NUM
easat-264	44	10	,	,	PUNCT
easat-264	44	11	2019	2019	NUM
easat-264	44	12	doi	doi	NOUN
easat-264	44	13	:	:	PUNCT
easat-264	44	14	10.33805/2576	10.33805/2576	NUM
easat-264	44	15	-	-	SYM
easat-264	44	16	8484.164	8484.164	NUM
easat-264	44	17	©	©	ADP
easat-264	44	18	2019	2019	NUM
easat-264	44	19	by	by	ADP
easat-264	44	20	the	the	DET
easat-264	44	21	author	author	NOUN
easat-264	44	22	figure	figure	NOUN
easat-264	44	23	7	7	NUM
easat-264	44	24	.	.	NOUN
easat-264	44	25	example	example	NOUN
easat-264	44	26	of	of	ADP
easat-264	44	27	a	a	DET
easat-264	44	28	protein	protein	NOUN
easat-264	44	29	profile	profile	NOUN
easat-264	44	30	.	.	PUNCT
easat-264	45	1	thanks	thank	NOUN
easat-264	45	2	to	to	ADP
easat-264	45	3	these	these	DET
easat-264	45	4	two	two	NUM
easat-264	45	5	types	type	NOUN
easat-264	45	6	of	of	ADP
easat-264	45	7	investigations	investigation	NOUN
easat-264	45	8	,	,	PUNCT
easat-264	45	9	which	which	PRON
easat-264	45	10	are	be	AUX
easat-264	45	11	essential	essential	ADJ
easat-264	45	12	for	for	ADP
easat-264	45	13	us	we	PRON
easat-264	45	14	,	,	PUNCT
easat-264	45	15	we	we	PRON
easat-264	45	16	can	can	AUX
easat-264	45	17	direct	direct	VERB
easat-264	45	18	the	the	DET
easat-264	45	19	biological	biological	ADJ
easat-264	45	20	diagnosis	diagnosis	NOUN
easat-264	45	21	more	more	ADV
easat-264	45	22	specifically	specifically	ADV
easat-264	45	23	towards	towards	ADP
easat-264	45	24	parameters	parameter	NOUN
easat-264	45	25	related	relate	VERB
easat-264	45	26	to	to	ADP
easat-264	45	27	microbiology	microbiology	NOUN
easat-264	45	28	,	,	PUNCT
easat-264	45	29	oncology	oncology	NOUN
easat-264	45	30	,	,	PUNCT
easat-264	45	31	allergy	allergy	NOUN
easat-264	45	32	,	,	PUNCT
easat-264	45	33	autoimmunity	autoimmunity	NOUN
easat-264	45	34	or	or	CCONJ
easat-264	45	35	metabolism	metabolism	NOUN
easat-264	45	36	(	(	PUNCT
easat-264	45	37	figure	figure	NOUN
easat-264	45	38	8)	8)	NUM
easat-264	45	39	.	.	PUNCT
easat-264	46	1	the	the	DET
easat-264	46	2	therapeutic	therapeutic	ADJ
easat-264	46	3	goal	goal	NOUN
easat-264	46	4	of	of	ADP
easat-264	46	5	the	the	DET
easat-264	46	6	bi(g)med	bi(g)med	PROPN
easat-264	46	7	is	be	AUX
easat-264	46	8	therefore	therefore	ADV
easat-264	46	9	to	to	PART
easat-264	46	10	make	make	VERB
easat-264	46	11	the	the	DET
easat-264	46	12	best	good	ADJ
easat-264	46	13	use	use	NOUN
easat-264	46	14	of	of	ADP
easat-264	46	15	all	all	DET
easat-264	46	16	the	the	DET
easat-264	46	17	molecular	molecular	ADJ
easat-264	46	18	resources	resource	NOUN
easat-264	46	19	available	available	ADJ
easat-264	46	20	in	in	ADP
easat-264	46	21	the	the	DET
easat-264	46	22	cell	cell	NOUN
easat-264	46	23	to	to	PART
easat-264	46	24	restore	restore	VERB
easat-264	46	25	its	its	PRON
easat-264	46	26	homeostasis	homeostasis	NOUN
easat-264	46	27	at	at	ADP
easat-264	46	28	the	the	DET
easat-264	46	29	different	different	ADJ
easat-264	46	30	genomic	genomic	NOUN
easat-264	46	31	,	,	PUNCT
easat-264	46	32	epigenomic	epigenomic	ADJ
easat-264	46	33	,	,	PUNCT
easat-264	46	34	transcriptomic	transcriptomic	ADJ
easat-264	46	35	,	,	PUNCT
easat-264	46	36	proteomic	proteomic	NOUN
easat-264	46	37	and	and	CCONJ
easat-264	46	38	metabolomic	metabolomic	ADJ
easat-264	46	39	levels	level	NOUN
easat-264	46	40	[	[	X
easat-264	46	41	16	16	NUM
easat-264	46	42	]	]	PUNCT
easat-264	46	43	.	.	PUNCT
easat-264	47	1	figure	figure	NOUN
easat-264	47	2	8	8	NUM
easat-264	47	3	.	.	PUNCT
easat-264	48	1	systems	system	NOUN
easat-264	48	2	biology	biology	NOUN
easat-264	48	3	of	of	ADP
easat-264	48	4	asthma	asthma	NOUN
easat-264	48	5	and	and	CCONJ
easat-264	48	6	allergic	allergic	ADJ
easat-264	48	7	diseases	disease	NOUN
easat-264	48	8	:	:	PUNCT
easat-264	48	9	a	a	DET
easat-264	48	10	multiscale	multiscale	ADJ
easat-264	48	11	approach	approach	NOUN
easat-264	48	12	[	[	X
easat-264	48	13	16	16	NUM
easat-264	48	14	]	]	PUNCT
easat-264	48	15	.	.	PUNCT
easat-264	49	1	to	to	PART
easat-264	49	2	achieve	achieve	VERB
easat-264	49	3	this	this	DET
easat-264	49	4	goal	goal	NOUN
easat-264	49	5	,	,	PUNCT
easat-264	49	6	it	it	PRON
easat-264	49	7	is	be	AUX
easat-264	49	8	necessary	necessary	ADJ
easat-264	49	9	to	to	PART
easat-264	49	10	use	use	VERB
easat-264	49	11	means	mean	NOUN
easat-264	49	12	borrowed	borrow	VERB
easat-264	49	13	to	to	ADP
easat-264	49	14	nanobiotechnologies	nanobiotechnologie	NOUN
easat-264	49	15	,	,	PUNCT
easat-264	49	16	to	to	PART
easat-264	49	17	ensure	ensure	VERB
easat-264	49	18	a	a	DET
easat-264	49	19	very	very	ADV
easat-264	49	20	efficient	efficient	ADJ
easat-264	49	21	transport	transport	NOUN
easat-264	49	22	of	of	ADP
easat-264	49	23	molecules	molecule	NOUN
easat-264	49	24	made	make	VERB
easat-264	49	25	available	available	ADJ
easat-264	49	26	to	to	ADP
easat-264	49	27	the	the	DET
easat-264	49	28	cells	cell	NOUN
easat-264	49	29	,	,	PUNCT
easat-264	49	30	so	so	SCONJ
easat-264	49	31	as	as	SCONJ
easat-264	49	32	to	to	PART
easat-264	49	33	facilitate	facilitate	VERB
easat-264	49	34	their	their	PRON
easat-264	49	35	self	self	NOUN
easat-264	49	36	-	-	PUNCT
easat-264	49	37	regulation	regulation	NOUN
easat-264	49	38	through	through	ADP
easat-264	49	39	a	a	DET
easat-264	49	40	truly	truly	ADV
easat-264	49	41	biomimetic	biomimetic	ADJ
easat-264	49	42	treatment	treatment	NOUN
easat-264	49	43	.	.	PUNCT
easat-264	50	1	usually	usually	ADV
easat-264	50	2	the	the	DET
easat-264	50	3	bi(g)med	bi(g)me	VERB
easat-264	50	4	uses	use	VERB
easat-264	50	5	nanovectors	nanovector	NOUN
easat-264	50	6	with	with	ADP
easat-264	50	7	a	a	DET
easat-264	50	8	xylitol	xylitol	NOUN
easat-264	50	9	base	base	NOUN
easat-264	50	10	[	[	X
easat-264	50	11	17	17	NUM
easat-264	50	12	]	]	PUNCT
easat-264	50	13	,	,	PUNCT
easat-264	50	14	carrying	carry	VERB
easat-264	50	15	molecules	molecule	NOUN
easat-264	50	16	of	of	ADP
easat-264	50	17	all	all	DET
easat-264	50	18	types	type	NOUN
easat-264	50	19	at	at	ADP
easat-264	50	20	ultra	ultra	ADJ
easat-264	50	21	-	-	ADJ
easat-264	50	22	low	low	ADJ
easat-264	50	23	concentrations	concentration	NOUN
easat-264	50	24	(	(	PUNCT
easat-264	50	25	1	1	NUM
easat-264	50	26	g	g	NOUN
easat-264	50	27	x10	x10	NOUN
easat-264	50	28	-	-	SYM
easat-264	50	29	4	4	NUM
easat-264	50	30	until	until	ADP
easat-264	50	31	1	1	NUM
easat-264	50	32	g	g	NOUN
easat-264	50	33	x10	x10	NOUN
easat-264	50	34	-	-	SYM
easat-264	50	35	10	10	NUM
easat-264	50	36	mol	mol	NOUN
easat-264	50	37	)	)	PUNCT
easat-264	50	38	.	.	PUNCT
easat-264	51	1	these	these	DET
easat-264	51	2	small	small	ADJ
easat-264	51	3	globules	globule	NOUN
easat-264	51	4	must	must	AUX
easat-264	51	5	be	be	AUX
easat-264	51	6	dissolved	dissolve	VERB
easat-264	51	7	in	in	ADP
easat-264	51	8	the	the	DET
easat-264	51	9	oral	oral	ADJ
easat-264	51	10	cavity	cavity	NOUN
easat-264	51	11	as	as	ADP
easat-264	51	12	in	in	ADP
easat-264	51	13	all	all	DET
easat-264	51	14	sub	sub	ADJ
easat-264	51	15	-	-	ADJ
easat-264	51	16	lingual	lingual	ADJ
easat-264	51	17	immunotherapies	immunotherapy	NOUN
easat-264	51	18	,	,	PUNCT
easat-264	51	19	from	from	ADP
easat-264	51	20	where	where	SCONJ
easat-264	51	21	the	the	DET
easat-264	51	22	molecular	molecular	ADJ
easat-264	51	23	information	information	NOUN
easat-264	51	24	will	will	AUX
easat-264	51	25	be	be	AUX
easat-264	51	26	transmitted	transmit	VERB
easat-264	51	27	to	to	ADP
easat-264	51	28	the	the	DET
easat-264	51	29	target	target	NOUN
easat-264	51	30	organ	organ	VERB
easat-264	51	31	via	via	ADP
easat-264	51	32	the	the	DET
easat-264	51	33	lymphatic	lymphatic	ADJ
easat-264	51	34	network	network	NOUN
easat-264	51	35	.	.	PUNCT
easat-264	52	1	these	these	DET
easat-264	52	2	molecules	molecule	NOUN
easat-264	52	3	can	can	AUX
easat-264	52	4	be	be	AUX
easat-264	52	5	fragments	fragment	NOUN
easat-264	52	6	of	of	ADP
easat-264	52	7	dna	dna	NOUN
easat-264	52	8	and	and	CCONJ
easat-264	52	9	rna	rna	PROPN
easat-264	52	10	(	(	PUNCT
easat-264	52	11	among	among	ADP
easat-264	52	12	these	these	PRON
easat-264	52	13	will	will	AUX
easat-264	52	14	be	be	AUX
easat-264	52	15	found	find	VERB
easat-264	52	16	mainly	mainly	ADV
easat-264	52	17	micrornas	microrna	NOUN
easat-264	52	18	as	as	ADP
easat-264	52	19	epigenetic	epigenetic	ADJ
easat-264	52	20	regulators	regulator	NOUN
easat-264	52	21	)	)	PUNCT
easat-264	52	22	,	,	PUNCT
easat-264	52	23	transcription	transcription	NOUN
easat-264	52	24	factors	factor	NOUN
easat-264	52	25	,	,	PUNCT
easat-264	52	26	all	all	DET
easat-264	52	27	kinds	kind	NOUN
easat-264	52	28	of	of	ADP
easat-264	52	29	molecules	molecule	NOUN
easat-264	52	30	involved	involve	VERB
easat-264	52	31	in	in	ADP
easat-264	52	32	the	the	DET
easat-264	52	33	various	various	ADJ
easat-264	52	34	cell	cell	NOUN
easat-264	52	35	signalling	signal	VERB
easat-264	52	36	pathways	pathway	NOUN
easat-264	52	37	,	,	PUNCT
easat-264	52	38	but	but	CCONJ
easat-264	52	39	also	also	ADV
easat-264	52	40	cytokines	cytokine	NOUN
easat-264	52	41	and	and	CCONJ
easat-264	52	42	enzymes	enzyme	NOUN
easat-264	52	43	such	such	ADJ
easat-264	52	44	as	as	ADP
easat-264	52	45	kinases	kinase	NOUN
easat-264	52	46	.	.	PUNCT
easat-264	53	1	all	all	PRON
easat-264	53	2	together	together	ADV
easat-264	53	3	are	be	AUX
easat-264	53	4	included	include	VERB
easat-264	53	5	in	in	ADP
easat-264	53	6	formulas	formula	NOUN
easat-264	53	7	in	in	ADP
easat-264	53	8	ultra	ultra	ADJ
easat-264	53	9	-	-	ADJ
easat-264	53	10	low	low	ADJ
easat-264	53	11	doses	dose	NOUN
easat-264	53	12	[	[	X
easat-264	53	13	18	18	NUM
easat-264	53	14	]	]	X
easat-264	53	15	;	;	PUNCT
easat-264	53	16	all	all	PRON
easat-264	53	17	are	be	AUX
easat-264	53	18	therefore	therefore	ADV
easat-264	53	19	at	at	ADP
easat-264	53	20	concentrations	concentration	NOUN
easat-264	53	21	similar	similar	ADJ
easat-264	53	22	to	to	ADP
easat-264	53	23	those	those	PRON
easat-264	53	24	observed	observe	VERB
easat-264	53	25	in	in	ADP
easat-264	53	26	the	the	DET
easat-264	53	27	cell	cell	NOUN
easat-264	53	28	physiology	physiology	NOUN
easat-264	53	29	,	,	PUNCT
easat-264	53	30	making	make	VERB
easat-264	53	31	them	they	PRON
easat-264	53	32	unlikely	unlikely	ADJ
easat-264	53	33	to	to	PART
easat-264	53	34	trigger	trigger	VERB
easat-264	53	35	unwanted	unwanted	ADJ
easat-264	53	36	side	side	NOUN
easat-264	53	37	reactions	reaction	NOUN
easat-264	53	38	.	.	PUNCT
easat-264	54	1	in	in	ADP
easat-264	54	2	this	this	DET
easat-264	54	3	way	way	NOUN
easat-264	54	4	we	we	PRON
easat-264	54	5	can	can	AUX
easat-264	54	6	progressively	progressively	ADV
easat-264	54	7	regulate	regulate	VERB
easat-264	54	8	most	most	ADJ
easat-264	54	9	of	of	ADP
easat-264	54	10	the	the	DET
easat-264	54	11	disturbed	disturb	VERB
easat-264	54	12	molecular	molecular	ADJ
easat-264	54	13	pathways	pathway	NOUN
easat-264	54	14	in	in	ADP
easat-264	54	15	one	one	NUM
easat-264	54	16	or	or	CCONJ
easat-264	54	17	more	more	ADJ
easat-264	54	18	given	give	VERB
easat-264	54	19	pathologies	pathology	NOUN
easat-264	54	20	according	accord	VERB
easat-264	54	21	to	to	ADP
easat-264	54	22	the	the	DET
easat-264	54	23	general	general	ADJ
easat-264	54	24	rule	rule	NOUN
easat-264	54	25	of	of	ADP
easat-264	54	26	our	our	PRON
easat-264	54	27	kind	kind	NOUN
easat-264	54	28	of	of	ADP
easat-264	54	29	treatment	treatment	NOUN
easat-264	54	30	:	:	PUNCT
easat-264	54	31	from	from	ADP
easat-264	54	32	the	the	DET
easat-264	54	33	gene	gene	NOUN
easat-264	54	34	to	to	ADP
easat-264	54	35	the	the	DET
easat-264	54	36	whole	whole	ADJ
easat-264	54	37	cell	cell	NOUN
easat-264	55	1	[	[	X
easat-264	55	2	19,20	19,20	NOUN
easat-264	55	3	]	]	PUNCT
easat-264	55	4	.	.	PUNCT
easat-264	56	1	3	3	X
easat-264	56	2	.	.	X
easat-264	56	3	results	result	VERB
easat-264	56	4	the	the	DET
easat-264	56	5	results	result	NOUN
easat-264	56	6	obtained	obtain	VERB
easat-264	56	7	with	with	ADP
easat-264	56	8	this	this	DET
easat-264	56	9	method	method	NOUN
easat-264	56	10	will	will	AUX
easat-264	56	11	be	be	AUX
easat-264	56	12	presented	present	VERB
easat-264	56	13	through	through	ADP
easat-264	56	14	three	three	NUM
easat-264	56	15	case	case	NOUN
easat-264	56	16	reports	report	VERB
easat-264	56	17	.	.	PUNCT
easat-264	57	1	3.1	3.1	NUM
easat-264	57	2	.	.	PUNCT
easat-264	57	3	primary	primary	ADJ
easat-264	57	4	biliary	biliary	NOUN
easat-264	57	5	cirrhosis	cirrhosis	NOUN
easat-264	57	6	(	(	PUNCT
easat-264	57	7	pbc	pbc	PROPN
easat-264	57	8	)	)	PUNCT
easat-264	57	9	and	and	CCONJ
easat-264	57	10	systemic	systemic	ADJ
easat-264	57	11	sclerosis	sclerosis	NOUN
easat-264	57	12	(	(	PUNCT
easat-264	57	13	ssc	ssc	NOUN
easat-264	57	14	)	)	PUNCT
easat-264	57	15	this	this	PRON
easat-264	57	16	is	be	AUX
easat-264	57	17	a	a	DET
easat-264	57	18	67	67	NUM
easat-264	57	19	-	-	PUNCT
easat-264	57	20	year	year	NOUN
easat-264	57	21	-	-	PUNCT
easat-264	57	22	old	old	ADJ
easat-264	57	23	woman	woman	NOUN
easat-264	57	24	at	at	ADP
easat-264	57	25	the	the	DET
easat-264	57	26	time	time	NOUN
easat-264	57	27	of	of	ADP
easat-264	57	28	her	her	PRON
easat-264	57	29	first	first	ADJ
easat-264	57	30	consultation	consultation	NOUN
easat-264	57	31	in	in	ADP
easat-264	57	32	2003	2003	NUM
easat-264	57	33	,	,	PUNCT
easat-264	57	34	by	by	ADP
easat-264	57	35	which	which	PRON
easat-264	57	36	a	a	DET
easat-264	57	37	primary	primary	ADJ
easat-264	57	38	biliary	biliary	NOUN
easat-264	57	39	cirrhosis	cirrhosis	NOUN
easat-264	57	40	(	(	PUNCT
easat-264	57	41	pbc	pbc	PROPN
easat-264	57	42	)	)	PUNCT
easat-264	57	43	and	and	CCONJ
easat-264	57	44	a	a	DET
easat-264	57	45	systemic	systemic	ADJ
easat-264	57	46	sclerosis	sclerosis	NOUN
easat-264	57	47	(	(	PUNCT
easat-264	57	48	ssc	ssc	NOUN
easat-264	57	49	)	)	PUNCT
easat-264	57	50	were	be	AUX
easat-264	57	51	recently	recently	ADV
easat-264	57	52	discovered	discover	VERB
easat-264	57	53	on	on	ADP
easat-264	57	54	the	the	DET
easat-264	57	55	occasion	occasion	NOUN
easat-264	57	56	of	of	ADP
easat-264	57	57	pericarditis	pericarditis	NOUN
easat-264	57	58	associated	associate	VERB
easat-264	57	59	with	with	ADP
easat-264	57	60	pleural	pleural	ADJ
easat-264	57	61	effusion	effusion	NOUN
easat-264	57	62	.	.	PUNCT
easat-264	58	1	at	at	ADP
easat-264	58	2	this	this	DET
easat-264	58	3	time	time	NOUN
easat-264	58	4	,	,	PUNCT
easat-264	58	5	biology	biology	NOUN
easat-264	58	6	shows	show	VERB
easat-264	58	7	the	the	DET
easat-264	58	8	usual	usual	ADJ
easat-264	58	9	abnormalities	abnormality	NOUN
easat-264	58	10	for	for	ADP
easat-264	58	11	this	this	DET
easat-264	58	12	type	type	NOUN
easat-264	58	13	of	of	ADP
easat-264	58	14	pathology	pathology	NOUN
easat-264	58	15	,	,	PUNCT
easat-264	58	16	namely	namely	ADV
easat-264	58	17	increased	increase	VERB
easat-264	58	18	antinuclear	antinuclear	ADJ
easat-264	58	19	and	and	CCONJ
easat-264	58	20	in	in	ADP
easat-264	58	21	particular	particular	ADJ
easat-264	58	22	anticentromere	anticentromere	ADJ
easat-264	58	23	antibodies	antibodie	VERB
easat-264	58	24	;	;	PUNCT
easat-264	58	25	it	it	PRON
easat-264	58	26	is	be	AUX
easat-264	58	27	the	the	DET
easat-264	58	28	same	same	ADJ
easat-264	58	29	with	with	ADP
easat-264	58	30	regard	regard	NOUN
easat-264	58	31	to	to	ADP
easat-264	58	32	anti	anti	ADJ
easat-264	58	33	-	-	ADJ
easat-264	58	34	mitochondrial	mitochondrial	ADJ
easat-264	58	35	antibodies	antibody	NOUN
easat-264	58	36	.	.	PUNCT
easat-264	59	1	it	it	PRON
easat-264	59	2	is	be	AUX
easat-264	59	3	also	also	ADV
easat-264	59	4	interesting	interesting	ADJ
easat-264	59	5	to	to	PART
easat-264	59	6	note	note	VERB
easat-264	59	7	the	the	DET
easat-264	59	8	viral	viral	ADJ
easat-264	59	9	reactivations	reactivation	NOUN
easat-264	59	10	concerning	concern	VERB
easat-264	59	11	ebv	ebv	NOUN
easat-264	59	12	,	,	PUNCT
easat-264	59	13	cmv	cmv	NOUN
easat-264	59	14	and	and	CCONJ
easat-264	59	15	parvovirus	parvovirus	NOUN
easat-264	59	16	b19	b19	NOUN
easat-264	59	17	,	,	PUNCT
easat-264	59	18	which	which	PRON
easat-264	59	19	will	will	AUX
easat-264	59	20	follow	follow	VERB
easat-264	59	21	the	the	DET
easat-264	59	22	patient	patient	NOUN
easat-264	59	23	in	in	ADP
easat-264	59	24	a	a	DET
easat-264	59	25	very	very	ADV
easat-264	59	26	irregular	irregular	ADJ
easat-264	59	27	way	way	NOUN
easat-264	59	28	during	during	ADP
easat-264	59	29	all	all	DET
easat-264	59	30	the	the	DET
easat-264	59	31	coming	come	VERB
easat-264	59	32	years	year	NOUN
easat-264	59	33	.	.	PUNCT
easat-264	60	1	the	the	DET
easat-264	60	2	diagnosis	diagnosis	NOUN
easat-264	60	3	is	be	AUX
easat-264	60	4	confirmed	confirm	VERB
easat-264	60	5	by	by	ADP
easat-264	60	6	tissue	tissue	NOUN
easat-264	60	7	biopsies	biopsy	NOUN
easat-264	60	8	,	,	PUNCT
easat-264	60	9	and	and	CCONJ
easat-264	60	10	the	the	DET
easat-264	60	11	patient	patient	NOUN
easat-264	60	12	wants	want	VERB
easat-264	60	13	to	to	PART
easat-264	60	14	stop	stop	VERB
easat-264	60	15	the	the	DET
easat-264	60	16	immediate	immediate	ADJ
easat-264	60	17	corticosteroid	corticosteroid	ADJ
easat-264	60	18	therapy	therapy	NOUN
easat-264	60	19	,	,	PUNCT
easat-264	60	20	while	while	SCONJ
easat-264	60	21	agreeing	agree	VERB
easat-264	60	22	to	to	PART
easat-264	60	23	continue	continue	VERB
easat-264	60	24	a	a	DET
easat-264	60	25	treatment	treatment	NOUN
easat-264	60	26	with	with	ADP
easat-264	60	27	ursodeoxycholic	ursodeoxycholic	PROPN
easat-264	60	28	acid	acid	NOUN
easat-264	60	29	,	,	PUNCT
easat-264	60	30	which	which	PRON
easat-264	60	31	she	she	PRON
easat-264	60	32	never	never	ADV
easat-264	60	33	interrupted	interrupt	VERB
easat-264	60	34	.	.	PUNCT
easat-264	61	1	for	for	ADP
easat-264	61	2	this	this	DET
easat-264	61	3	reason	reason	NOUN
easat-264	61	4	,	,	PUNCT
easat-264	61	5	we	we	PRON
easat-264	61	6	initiated	initiate	VERB
easat-264	61	7	a	a	DET
easat-264	61	8	treatment	treatment	NOUN
easat-264	61	9	with	with	ADP
easat-264	61	10	bi(g)med	bi(g)me	VERB
easat-264	61	11	essentially	essentially	ADV
easat-264	61	12	oriented	orient	VERB
easat-264	61	13	towards	towards	ADP
easat-264	61	14	the	the	DET
easat-264	61	15	regulation	regulation	NOUN
easat-264	61	16	of	of	ADP
easat-264	61	17	the	the	DET
easat-264	61	18	autoimmunity	autoimmunity	NOUN
easat-264	61	19	processes	process	NOUN
easat-264	61	20	and	and	CCONJ
easat-264	61	21	the	the	DET
easat-264	61	22	neutralization	neutralization	NOUN
easat-264	61	23	of	of	ADP
easat-264	61	24	the	the	DET
easat-264	61	25	various	various	ADJ
easat-264	61	26	reactivated	reactivate	VERB
easat-264	61	27	viruses	virus	NOUN
easat-264	61	28	mentioned	mention	VERB
easat-264	61	29	above	above	ADV
easat-264	61	30	.	.	PUNCT
easat-264	62	1	the	the	DET
easat-264	62	2	clinical	clinical	ADJ
easat-264	62	3	evolution	evolution	NOUN
easat-264	62	4	has	have	AUX
easat-264	62	5	shown	show	VERB
easat-264	62	6	a	a	DET
easat-264	62	7	remarkable	remarkable	ADJ
easat-264	62	8	stability	stability	NOUN
easat-264	62	9	even	even	ADV
easat-264	62	10	if	if	SCONJ
easat-264	62	11	it	it	PRON
easat-264	62	12	has	have	AUX
easat-264	62	13	been	be	AUX
easat-264	62	14	complicated	complicate	VERB
easat-264	62	15	by	by	ADP
easat-264	62	16	various	various	ADJ
easat-264	62	17	accidents	accident	NOUN
easat-264	62	18	such	such	ADJ
easat-264	62	19	as	as	ADP
easat-264	62	20	:	:	PUNCT
easat-264	62	21	•	•	NUM
easat-264	62	22	the	the	DET
easat-264	62	23	early	early	ADJ
easat-264	62	24	development	development	NOUN
easat-264	62	25	of	of	ADP
easat-264	62	26	a	a	DET
easat-264	62	27	xerostomia	xerostomia	NOUN
easat-264	62	28	,	,	PUNCT
easat-264	62	29	itself	itself	PRON
easat-264	62	30	causing	cause	VERB
easat-264	62	31	recurrent	recurrent	ADJ
easat-264	62	32	problems	problem	NOUN
easat-264	62	33	of	of	ADP
easat-264	62	34	periodontal	periodontal	ADJ
easat-264	62	35	diseases	disease	NOUN
easat-264	62	36	and	and	CCONJ
easat-264	62	37	dental	dental	ADJ
easat-264	62	38	infections	infection	NOUN
easat-264	62	39	at	at	ADP
easat-264	62	40	the	the	DET
easat-264	62	41	origin	origin	NOUN
easat-264	62	42	of	of	ADP
easat-264	62	43	numerous	numerous	ADJ
easat-264	62	44	local	local	ADJ
easat-264	62	45	treatments	treatment	NOUN
easat-264	62	46	•	•	ADP
easat-264	62	47	the	the	DET
easat-264	62	48	accidental	accidental	ADJ
easat-264	62	49	discovery	discovery	NOUN
easat-264	62	50	in	in	ADP
easat-264	62	51	2010	2010	NUM
easat-264	62	52	of	of	ADP
easat-264	62	53	a	a	DET
easat-264	62	54	ductal	ductal	ADJ
easat-264	62	55	adenocarcinoma	adenocarcinoma	NOUN
easat-264	62	56	of	of	ADP
easat-264	62	57	the	the	DET
easat-264	62	58	left	left	ADJ
easat-264	62	59	breast	breast	NOUN
easat-264	62	60	requiring	require	VERB
easat-264	62	61	a	a	DET
easat-264	62	62	lumpectomy	lumpectomy	NOUN
easat-264	62	63	followed	follow	VERB
easat-264	62	64	by	by	ADP
easat-264	62	65	the	the	DET
easat-264	62	66	establishment	establishment	NOUN
easat-264	62	67	of	of	ADP
easat-264	62	68	an	an	DET
easat-264	62	69	appropriate	appropriate	ADJ
easat-264	62	70	bi(g)med	bi(g)me	VERB
easat-264	62	71	-	-	PUNCT
easat-264	62	72	immunogenetic	immunogenetic	ADJ
easat-264	62	73	regulation	regulation	NOUN
easat-264	62	74	•	•	ADP
easat-264	62	75	the	the	DET
easat-264	62	76	sudden	sudden	ADJ
easat-264	62	77	appearance	appearance	NOUN
easat-264	62	78	in	in	ADP
easat-264	62	79	2014	2014	NUM
easat-264	62	80	of	of	ADP
easat-264	62	81	an	an	DET
easat-264	62	82	autoimmune	autoimmune	ADJ
easat-264	62	83	thrombocytopenia	thrombocytopenia	NOUN
easat-264	62	84	following	follow	VERB
easat-264	62	85	osteosynthesis	osteosynthesis	NOUN
easat-264	62	86	after	after	ADP
easat-264	62	87	traumatic	traumatic	ADJ
easat-264	62	88	wrist	wrist	NOUN
easat-264	62	89	fracture	fracture	PROPN
easat-264	62	90	and	and	CCONJ
easat-264	62	91	needing	need	VERB
easat-264	62	92	the	the	DET
easat-264	62	93	establishment	establishment	NOUN
easat-264	62	94	of	of	ADP
easat-264	62	95	an	an	DET
easat-264	62	96	additional	additional	ADJ
easat-264	62	97	regulatory	regulatory	ADJ
easat-264	62	98	treatment	treatment	NOUN
easat-264	62	99	to	to	PART
easat-264	62	100	stabilize	stabilize	VERB
easat-264	62	101	platelets	platelet	NOUN
easat-264	62	102	between	between	ADP
easat-264	62	103	30	30	NUM
easat-264	62	104	and	and	CCONJ
easat-264	62	105	40	40	NUM
easat-264	62	106	thousand	thousand	NUM
easat-264	62	107	•	•	NUM
easat-264	62	108	the	the	DET
easat-264	62	109	occurrence	occurrence	NOUN
easat-264	62	110	in	in	ADP
easat-264	62	111	2017	2017	NUM
easat-264	62	112	of	of	ADP
easat-264	62	113	several	several	ADJ
easat-264	62	114	episodes	episode	NOUN
easat-264	62	115	of	of	ADP
easat-264	62	116	bacterial	bacterial	ADJ
easat-264	62	117	pulmonary	pulmonary	ADJ
easat-264	62	118	infections	infection	NOUN
easat-264	62	119	which	which	PRON
easat-264	62	120	each	each	DET
easat-264	62	121	time	time	NOUN
easat-264	62	122	required	require	VERB
easat-264	62	123	the	the	DET
easat-264	62	124	use	use	NOUN
easat-264	62	125	of	of	ADP
easat-264	62	126	appropriate	appropriate	ADJ
easat-264	62	127	antibiotic	antibiotic	ADJ
easat-264	62	128	therapy	therapy	NOUN
easat-264	62	129	despite	despite	SCONJ
easat-264	62	130	all	all	DET
easat-264	62	131	these	these	DET
easat-264	62	132	health	health	NOUN
easat-264	62	133	disorders	disorder	NOUN
easat-264	62	134	,	,	PUNCT
easat-264	62	135	that	that	SCONJ
easat-264	62	136	adjustments	adjustment	NOUN
easat-264	62	137	at	at	ADP
easat-264	62	138	the	the	DET
easat-264	62	139	level	level	NOUN
easat-264	62	140	of	of	ADP
easat-264	62	141	the	the	DET
easat-264	62	142	bi(g)med	bi(g)me	VERB
easat-264	62	143	nanotherapy	nanotherapy	NOUN
easat-264	62	144	have	have	AUX
easat-264	62	145	each	each	DET
easat-264	62	146	time	time	NOUN
easat-264	62	147	contributed	contribute	VERB
easat-264	62	148	to	to	ADP
easat-264	62	149	rebalance	rebalance	NOUN
easat-264	62	150	,	,	PUNCT
easat-264	62	151	the	the	DET
easat-264	62	152	patient	patient	NOUN
easat-264	62	153	has	have	AUX
easat-264	62	154	preserved	preserve	VERB
easat-264	62	155	until	until	ADP
easat-264	62	156	now	now	ADV
easat-264	62	157	a	a	DET
easat-264	62	158	very	very	ADV
easat-264	62	159	stable	stable	ADJ
easat-264	62	160	condition	condition	NOUN
easat-264	62	161	and	and	CCONJ
easat-264	62	162	a	a	DET
easat-264	62	163	biological	biological	ADJ
easat-264	62	164	state	state	NOUN
easat-264	62	165	hardly	hardly	ADV
easat-264	62	166	evolutive	evolutive	ADJ
easat-264	62	167	,	,	PUNCT
easat-264	62	168	where	where	SCONJ
easat-264	62	169	the	the	DET
easat-264	62	170	various	various	ADJ
easat-264	62	171	parameters	parameter	NOUN
easat-264	62	172	alternately	alternately	ADV
easat-264	62	173	normalize	normalize	VERB
easat-264	62	174	and	and	CCONJ
easat-264	62	175	then	then	ADV
easat-264	62	176	degrade	degrade	VERB
easat-264	62	177	again	again	ADV
easat-264	62	178	more	more	ADV
easat-264	62	179	or	or	CCONJ
easat-264	62	180	less	less	ADJ
easat-264	62	181	.	.	PUNCT
easat-264	63	1	pbc	pbc	PROPN
easat-264	63	2	and	and	CCONJ
easat-264	63	3	ssc	ssc	PROPN
easat-264	63	4	remained	remained	AUX
easat-264	63	5	perfectly	perfectly	ADV
easat-264	63	6	stabilized	stabilize	VERB
easat-264	63	7	during	during	ADP
easat-264	63	8	all	all	DET
easat-264	63	9	these	these	DET
easat-264	63	10	years	year	NOUN
easat-264	63	11	.	.	PUNCT
easat-264	64	1	3.2	3.2	NUM
easat-264	64	2	.	.	PUNCT
easat-264	65	1	waldenström‘s	waldenström‘s	PROPN
easat-264	65	2	macroglobulinemia	macroglobulinemia	VERB
easat-264	65	3	the	the	DET
easat-264	65	4	second	second	ADJ
easat-264	65	5	example	example	NOUN
easat-264	65	6	is	be	AUX
easat-264	65	7	that	that	PRON
easat-264	65	8	of	of	ADP
easat-264	65	9	a	a	DET
easat-264	65	10	53	53	NUM
easat-264	65	11	-	-	PUNCT
easat-264	65	12	year	year	NOUN
easat-264	65	13	-	-	PUNCT
easat-264	65	14	old	old	ADJ
easat-264	65	15	woman	woman	NOUN
easat-264	65	16	at	at	ADP
easat-264	65	17	the	the	DET
easat-264	65	18	time	time	NOUN
easat-264	65	19	of	of	ADP
easat-264	65	20	her	her	PRON
easat-264	65	21	first	first	ADJ
easat-264	65	22	consultation	consultation	NOUN
easat-264	65	23	in	in	ADP
easat-264	65	24	2012	2012	NUM
easat-264	65	25	,	,	PUNCT
easat-264	65	26	by	by	ADP
easat-264	65	27	which	which	PRON
easat-264	65	28	a	a	DET
easat-264	65	29	waldenström‘s	waldenström‘s	NOUN
easat-264	65	30	macroglobulinemia	macroglobulinemia	PROPN
easat-264	65	31	was	be	AUX
easat-264	65	32	discovered	discover	VERB
easat-264	65	33	a	a	DET
easat-264	65	34	few	few	ADJ
easat-264	65	35	months	month	NOUN
easat-264	65	36	ago	ago	ADV
easat-264	65	37	in	in	ADP
easat-264	65	38	the	the	DET
easat-264	65	39	course	course	NOUN
easat-264	65	40	of	of	ADP
easat-264	65	41	investigations	investigation	NOUN
easat-264	65	42	carried	carry	VERB
easat-264	65	43	out	out	ADP
easat-264	65	44	following	follow	VERB
easat-264	65	45	multiple	multiple	ADJ
easat-264	65	46	recurrent	recurrent	ADJ
easat-264	65	47	ent	ent	NOUN
easat-264	65	48	(	(	PUNCT
easat-264	65	49	ear	ear	NOUN
easat-264	65	50	,	,	PUNCT
easat-264	65	51	nose	nose	NOUN
easat-264	65	52	and	and	CCONJ
easat-264	65	53	throat	throat	NOUN
easat-264	65	54	)	)	PUNCT
easat-264	65	55	infections	infection	NOUN
easat-264	65	56	.	.	PUNCT
easat-264	66	1	the	the	DET
easat-264	66	2	first	first	ADJ
easat-264	66	3	biological	biological	ADJ
easat-264	66	4	parameters	parameter	NOUN
easat-264	66	5	corroborate	corroborate	VERB
easat-264	66	6	a	a	DET
easat-264	66	7	triple	triple	ADJ
easat-264	66	8	monoclonal	monoclonal	NOUN
easat-264	66	9	peak	peak	NOUN
easat-264	66	10	estimated	estimate	VERB
easat-264	66	11	at	at	ADP
easat-264	66	12	13.42	13.42	NUM
easat-264	66	13	g	g	NOUN
easat-264	66	14	/	/	SYM
easat-264	66	15	l	l	NOUN
easat-264	66	16	and	and	CCONJ
easat-264	66	17	including	include	VERB
easat-264	66	18	:	:	PUNCT
easat-264	66	19	•	•	NUM
easat-264	66	20	igg	igg	PROPN
easat-264	66	21	kappa	kappa	PROPN
easat-264	66	22	•	•	PROPN
easat-264	66	23	iga	iga	PROPN
easat-264	66	24	kappa	kappa	PROPN
easat-264	66	25	•	•	PROPN
easat-264	66	26	igm	igm	PROPN
easat-264	66	27	kappa	kappa	PROPN
easat-264	66	28	associated	associate	VERB
easat-264	66	29	with	with	ADP
easat-264	66	30	a	a	DET
easat-264	66	31	positive	positive	ADJ
easat-264	66	32	bence	bence	NOUN
easat-264	66	33	-	-	PUNCT
easat-264	66	34	jones	jones	NOUN
easat-264	66	35	proteinuria	proteinuria	PROPN
easat-264	66	36	and	and	CCONJ
easat-264	66	37	an	an	DET
easat-264	66	38	increased	increase	VERB
easat-264	66	39	value	value	NOUN
easat-264	66	40	of	of	ADP
easat-264	66	41	thymidine	thymidine	ADJ
easat-264	66	42	kinase	kinase	NOUN
easat-264	66	43	by	by	ADP
easat-264	66	44	10,2	10,2	NUM
easat-264	66	45	u	u	PROPN
easat-264	66	46	/	/	SYM
easat-264	66	47	l.	l.	NOUN
easat-264	66	48	after	after	ADP
easat-264	66	49	approximately	approximately	ADV
easat-264	66	50	eighteen	eighteen	NUM
easat-264	66	51	months	month	NOUN
easat-264	66	52	of	of	ADP
easat-264	66	53	a	a	DET
easat-264	66	54	bi(g)med	bi(g)me	VERB
easat-264	66	55	sublingual	sublingual	ADJ
easat-264	66	56	regulatory	regulatory	PROPN
easat-264	66	57	nanotherapy	nanotherapy	NOUN
easat-264	66	58	,	,	PUNCT
easat-264	66	59	the	the	DET
easat-264	66	60	triple	triple	ADJ
easat-264	66	61	monoclonal	monoclonal	NOUN
easat-264	66	62	peak	peak	NOUN
easat-264	66	63	had	have	AUX
easat-264	66	64	decreased	decrease	VERB
easat-264	66	65	to	to	ADP
easat-264	66	66	3.3	3.3	NUM
easat-264	66	67	g	g	NOUN
easat-264	66	68	/	/	SYM
easat-264	66	69	l	l	NOUN
easat-264	66	70	,	,	PUNCT
easat-264	66	71	bence	bence	NOUN
easat-264	66	72	-	-	PUNCT
easat-264	66	73	jones	jones	PROPN
easat-264	66	74	proteinuria	proteinuria	PROPN
easat-264	66	75	had	have	AUX
easat-264	66	76	disappeared	disappear	VERB
easat-264	66	77	,	,	PUNCT
easat-264	66	78	and	and	CCONJ
easat-264	66	79	thymidine	thymidine	PROPN
easat-264	66	80	kinase	kinase	PROPN
easat-264	66	81	was	be	AUX
easat-264	66	82	normal	normal	ADJ
easat-264	66	83	to	to	ADP
easat-264	66	84	5.0	5.0	NUM
easat-264	66	85	u	u	NOUN
easat-264	66	86	/	/	SYM
easat-264	66	87	l.	l.	NOUN
easat-264	66	88	in	in	ADP
easat-264	66	89	addition	addition	NOUN
easat-264	66	90	,	,	PUNCT
easat-264	66	91	the	the	DET
easat-264	66	92	patient	patient	NOUN
easat-264	66	93	had	have	AUX
easat-264	66	94	not	not	PART
easat-264	66	95	had	have	VERB
easat-264	66	96	the	the	DET
easat-264	66	97	least	least	ADJ
easat-264	66	98	ent	ent	NOUN
easat-264	66	99	infections	infection	NOUN
easat-264	66	100	during	during	ADP
easat-264	66	101	the	the	DET
easat-264	66	102	previous	previous	ADJ
easat-264	66	103	winter	winter	NOUN
easat-264	66	104	.	.	PUNCT
easat-264	67	1	from	from	ADP
easat-264	67	2	that	that	DET
easat-264	67	3	time	time	NOUN
easat-264	67	4	on	on	ADP
easat-264	67	5	,	,	PUNCT
easat-264	67	6	no	no	DET
easat-264	67	7	pejorative	pejorative	ADJ
easat-264	67	8	developments	development	NOUN
easat-264	67	9	have	have	AUX
easat-264	67	10	been	be	AUX
easat-264	67	11	reported	report	VERB
easat-264	67	12	.	.	PUNCT
easat-264	68	1	3.3	3.3	NUM
easat-264	68	2	.	.	PUNCT
easat-264	69	1	waldenström	waldenström	ADJ
easat-264	69	2	disease	disease	NOUN
easat-264	69	3	and	and	CCONJ
easat-264	69	4	sclerosing	sclerose	VERB
easat-264	69	5	cholangitis	cholangiti	NOUN
easat-264	69	6	a	a	DET
easat-264	69	7	third	third	ADJ
easat-264	69	8	and	and	CCONJ
easat-264	69	9	final	final	ADJ
easat-264	69	10	example	example	NOUN
easat-264	69	11	concerns	concern	VERB
easat-264	69	12	a	a	DET
easat-264	69	13	55	55	NUM
easat-264	69	14	-	-	PUNCT
easat-264	69	15	year	year	NOUN
easat-264	69	16	-	-	PUNCT
easat-264	69	17	old	old	ADJ
easat-264	69	18	man	man	NOUN
easat-264	69	19	at	at	ADP
easat-264	69	20	his	his	PRON
easat-264	69	21	first	first	ADJ
easat-264	69	22	consultation	consultation	NOUN
easat-264	69	23	for	for	ADP
easat-264	69	24	waldenström	waldenström	ADJ
easat-264	69	25	disease	disease	NOUN
easat-264	69	26	and	and	CCONJ
easat-264	69	27	sclerosing	sclerose	VERB
easat-264	69	28	cholangitis	cholangitis	NOUN
easat-264	69	29	discovered	discover	VERB
easat-264	69	30	the	the	DET
easat-264	69	31	previous	previous	ADJ
easat-264	69	32	year	year	NOUN
easat-264	69	33	.	.	PUNCT
easat-264	70	1	otherwise	otherwise	ADV
easat-264	70	2	an	an	DET
easat-264	70	3	ulcerative	ulcerative	ADJ
easat-264	70	4	colitis	colitis	NOUN
easat-264	70	5	has	have	AUX
easat-264	70	6	been	be	AUX
easat-264	70	7	known	know	VERB
easat-264	70	8	since	since	SCONJ
easat-264	70	9	the	the	DET
easat-264	70	10	age	age	NOUN
easat-264	70	11	of	of	ADP
easat-264	70	12	22	22	NUM
easat-264	70	13	and	and	CCONJ
easat-264	70	14	is	be	AUX
easat-264	70	15	regularly	regularly	ADV
easat-264	70	16	treated	treat	VERB
easat-264	70	17	by	by	ADP
easat-264	70	18	mesalazine	mesalazine	PROPN
easat-264	70	19	.	.	PUNCT
easat-264	71	1	at	at	ADP
easat-264	71	2	this	this	DET
easat-264	71	3	time	time	NOUN
easat-264	71	4	,	,	PUNCT
easat-264	71	5	its	its	PRON
easat-264	71	6	clinical	clinical	ADJ
easat-264	71	7	condition	condition	NOUN
easat-264	71	8	is	be	AUX
easat-264	71	9	not	not	PART
easat-264	71	10	bad	bad	ADJ
easat-264	71	11	,	,	PUNCT
easat-264	71	12	but	but	CCONJ
easat-264	71	13	the	the	DET
easat-264	71	14	biological	biological	ADJ
easat-264	71	15	parameters	parameter	NOUN
easat-264	71	16	show	show	VERB
easat-264	71	17	the	the	DET
easat-264	71	18	typical	typical	ADJ
easat-264	71	19	disturbances	disturbance	NOUN
easat-264	71	20	of	of	ADP
easat-264	71	21	the	the	DET
easat-264	71	22	diagnosed	diagnose	VERB
easat-264	71	23	diseases	disease	NOUN
easat-264	71	24	with	with	ADP
easat-264	71	25	:	:	PUNCT
easat-264	71	26	•	•	NUM
easat-264	71	27	increased	increase	VERB
easat-264	71	28	levels	level	NOUN
easat-264	71	29	of	of	ADP
easat-264	71	30	liver	liver	NOUN
easat-264	71	31	enzymes	enzyme	NOUN
easat-264	71	32	29	29	NUM
easat-264	71	33	edelweiss	edelweiss	PROPN
easat-264	71	34	applied	apply	VERB
easat-264	71	35	science	science	NOUN
easat-264	71	36	and	and	CCONJ
easat-264	71	37	technology	technology	NOUN
easat-264	71	38	issn	issn	PROPN
easat-264	71	39	:	:	PUNCT
easat-264	71	40	2576	2576	NUM
easat-264	71	41	-	-	SYM
easat-264	71	42	8484	8484	NUM
easat-264	71	43	vol	vol	NOUN
easat-264	71	44	.	.	PROPN
easat-264	72	1	3	3	NUM
easat-264	72	2	,	,	PUNCT
easat-264	72	3	no	no	INTJ
easat-264	72	4	.	.	NOUN
easat-264	72	5	1	1	NUM
easat-264	72	6	:	:	SYM
easat-264	72	7	26	26	NUM
easat-264	72	8	-	-	SYM
easat-264	72	9	29	29	NUM
easat-264	72	10	,	,	PUNCT
easat-264	72	11	2019	2019	NUM
easat-264	72	12	doi	doi	NOUN
easat-264	72	13	:	:	PUNCT
easat-264	72	14	10.33805/2576	10.33805/2576	NUM
easat-264	72	15	-	-	SYM
easat-264	72	16	8484.164	8484.164	NUM
easat-264	72	17	©	©	ADP
easat-264	72	18	2019	2019	NUM
easat-264	72	19	by	by	ADP
easat-264	72	20	the	the	DET
easat-264	72	21	author	author	NOUN
easat-264	72	22	•	•	ADP
easat-264	72	23	igm	igm	PROPN
easat-264	72	24	greatly	greatly	ADV
easat-264	72	25	increased	increase	VERB
easat-264	72	26	•	•	NUM
easat-264	72	27	positive	positive	ADJ
easat-264	72	28	p	p	NOUN
easat-264	72	29	-	-	PUNCT
easat-264	72	30	anca	anca	NOUN
easat-264	72	31	there	there	PRON
easat-264	72	32	is	be	VERB
easat-264	72	33	also	also	ADV
easat-264	72	34	a	a	DET
easat-264	72	35	reactivation	reactivation	NOUN
easat-264	72	36	of	of	ADP
easat-264	72	37	parvovirus	parvovirus	NOUN
easat-264	72	38	b19	b19	NOUN
easat-264	72	39	.	.	PUNCT
easat-264	73	1	the	the	DET
easat-264	73	2	patient	patient	NOUN
easat-264	73	3	followed	follow	VERB
easat-264	73	4	for	for	ADP
easat-264	73	5	a	a	DET
easat-264	73	6	year	year	NOUN
easat-264	73	7	and	and	CCONJ
easat-264	73	8	a	a	DET
easat-264	73	9	half	half	NOUN
easat-264	73	10	a	a	DET
easat-264	73	11	regulatory	regulatory	ADJ
easat-264	73	12	treatment	treatment	NOUN
easat-264	73	13	of	of	ADP
easat-264	73	14	bi(g)med	bi(g)me	VERB
easat-264	73	15	nanotherapy	nanotherapy	NOUN
easat-264	73	16	while	while	SCONJ
easat-264	73	17	continuing	continue	VERB
easat-264	73	18	his	his	PRON
easat-264	73	19	regular	regular	ADJ
easat-264	73	20	intake	intake	NOUN
easat-264	73	21	(	(	PUNCT
easat-264	73	22	but	but	CCONJ
easat-264	73	23	at	at	ADP
easat-264	73	24	a	a	DET
easat-264	73	25	very	very	ADV
easat-264	73	26	reduced	reduce	VERB
easat-264	73	27	dosage	dosage	NOUN
easat-264	73	28	)	)	PUNCT
easat-264	73	29	of	of	ADP
easat-264	73	30	mesalazine	mesalazine	NOUN
easat-264	73	31	and	and	CCONJ
easat-264	73	32	ursodesoxycholic	ursodesoxycholic	ADJ
easat-264	73	33	acid	acid	NOUN
easat-264	73	34	,	,	PUNCT
easat-264	73	35	and	and	CCONJ
easat-264	73	36	results	result	NOUN
easat-264	73	37	in	in	ADP
easat-264	73	38	biological	biological	ADJ
easat-264	73	39	parameters	parameter	NOUN
easat-264	73	40	almost	almost	ADV
easat-264	73	41	normalized	normalize	VERB
easat-264	73	42	among	among	ADP
easat-264	73	43	those	those	PRON
easat-264	73	44	initially	initially	ADV
easat-264	73	45	disturbed	disturb	VERB
easat-264	73	46	.	.	PUNCT
easat-264	74	1	4	4	X
easat-264	74	2	.	.	X
easat-264	74	3	discussion	discussion	NOUN
easat-264	74	4	this	this	DET
easat-264	74	5	brief	brief	ADJ
easat-264	74	6	description	description	NOUN
easat-264	74	7	of	of	ADP
easat-264	74	8	three	three	NUM
easat-264	74	9	clinical	clinical	ADJ
easat-264	74	10	examples	example	NOUN
easat-264	74	11	drawn	draw	VERB
easat-264	74	12	from	from	ADP
easat-264	74	13	a	a	DET
easat-264	74	14	daily	daily	ADJ
easat-264	74	15	medical	medical	ADJ
easat-264	74	16	practice	practice	NOUN
easat-264	74	17	make	make	VERB
easat-264	74	18	it	it	PRON
easat-264	74	19	possible	possible	ADJ
easat-264	74	20	to	to	PART
easat-264	74	21	demonstrate	demonstrate	VERB
easat-264	74	22	the	the	DET
easat-264	74	23	therapeutic	therapeutic	ADJ
easat-264	74	24	interest	interest	NOUN
easat-264	74	25	and	and	CCONJ
easat-264	74	26	effectiveness	effectiveness	NOUN
easat-264	74	27	of	of	ADP
easat-264	74	28	resorting	resort	VERB
easat-264	74	29	to	to	ADP
easat-264	74	30	the	the	DET
easat-264	74	31	regulating	regulate	VERB
easat-264	74	32	potential	potential	NOUN
easat-264	74	33	of	of	ADP
easat-264	74	34	the	the	DET
easat-264	74	35	cell	cell	NOUN
easat-264	74	36	itself	itself	PRON
easat-264	74	37	,	,	PUNCT
easat-264	74	38	the	the	DET
easat-264	74	39	only	only	ADJ
easat-264	74	40	one	one	NOUN
easat-264	74	41	able	able	ADJ
easat-264	74	42	to	to	PART
easat-264	74	43	rebalance	rebalance	VERB
easat-264	74	44	a	a	DET
easat-264	74	45	disturbed	disturbed	ADJ
easat-264	74	46	mode	mode	NOUN
easat-264	74	47	of	of	ADP
easat-264	74	48	functioning	function	VERB
easat-264	74	49	,	,	PUNCT
easat-264	74	50	when	when	SCONJ
easat-264	74	51	the	the	DET
easat-264	74	52	needed	need	VERB
easat-264	74	53	molecular	molecular	ADJ
easat-264	74	54	information	information	NOUN
easat-264	74	55	is	be	AUX
easat-264	74	56	provided	provide	VERB
easat-264	74	57	to	to	ADP
easat-264	74	58	it	it	PRON
easat-264	74	59	.	.	PUNCT
easat-264	75	1	it	it	PRON
easat-264	75	2	turns	turn	VERB
easat-264	75	3	out	out	ADP
easat-264	75	4	that	that	SCONJ
easat-264	75	5	this	this	DET
easat-264	75	6	regulatory	regulatory	ADJ
easat-264	75	7	capacity	capacity	NOUN
easat-264	75	8	is	be	AUX
easat-264	75	9	as	as	ADV
easat-264	75	10	greater	great	ADJ
easat-264	75	11	as	as	SCONJ
easat-264	75	12	the	the	DET
easat-264	75	13	molecular	molecular	ADJ
easat-264	75	14	resources	resource	NOUN
easat-264	75	15	used	use	VERB
easat-264	75	16	by	by	ADP
easat-264	75	17	the	the	DET
easat-264	75	18	cell	cell	NOUN
easat-264	75	19	for	for	ADP
easat-264	75	20	this	this	DET
easat-264	75	21	purpose	purpose	NOUN
easat-264	75	22	of	of	ADP
easat-264	75	23	global	global	ADJ
easat-264	75	24	regulation	regulation	NOUN
easat-264	75	25	are	be	AUX
easat-264	75	26	made	make	VERB
easat-264	75	27	available	available	ADJ
easat-264	75	28	by	by	ADP
easat-264	75	29	means	mean	NOUN
easat-264	75	30	of	of	ADP
easat-264	75	31	ultra	ultra	ADJ
easat-264	75	32	-	-	ADJ
easat-264	75	33	low	low	ADJ
easat-264	75	34	doses	dose	NOUN
easat-264	75	35	of	of	ADP
easat-264	75	36	nanotherapeutic	nanotherapeutic	ADJ
easat-264	75	37	compounds	compound	NOUN
easat-264	75	38	administered	administer	VERB
easat-264	75	39	sublingually	sublingually	ADV
easat-264	75	40	.	.	PUNCT
easat-264	76	1	this	this	DET
easat-264	76	2	observation	observation	NOUN
easat-264	76	3	does	do	AUX
easat-264	76	4	not	not	PART
easat-264	76	5	exclude	exclude	VERB
easat-264	76	6	that	that	SCONJ
easat-264	76	7	other	other	ADJ
easat-264	76	8	types	type	NOUN
easat-264	76	9	of	of	ADP
easat-264	76	10	nanocarriers	nanocarrier	NOUN
easat-264	76	11	could	could	AUX
easat-264	76	12	be	be	AUX
easat-264	76	13	considered	consider	VERB
easat-264	76	14	in	in	ADP
easat-264	76	15	the	the	DET
easat-264	76	16	near	near	ADJ
easat-264	76	17	future	future	NOUN
easat-264	76	18	.	.	PUNCT
easat-264	77	1	5	5	X
easat-264	77	2	.	.	X
easat-264	77	3	conclusion	conclusion	NOUN
easat-264	77	4	1	1	NUM
easat-264	77	5	.	.	PUNCT
easat-264	78	1	different	different	ADJ
easat-264	78	2	medical	medical	ADJ
easat-264	78	3	concepts	concept	NOUN
easat-264	78	4	have	have	AUX
easat-264	78	5	emerged	emerge	VERB
easat-264	78	6	in	in	ADP
easat-264	78	7	recent	recent	ADJ
easat-264	78	8	years	year	NOUN
easat-264	78	9	all	all	PRON
easat-264	78	10	based	base	VERB
easat-264	78	11	on	on	ADP
easat-264	78	12	globality	globality	NOUN
easat-264	78	13	and	and	CCONJ
easat-264	78	14	interactivity	interactivity	NOUN
easat-264	78	15	2	2	NUM
easat-264	78	16	.	.	PUNCT
easat-264	78	17	personalized	personalized	ADJ
easat-264	78	18	medicine	medicine	NOUN
easat-264	78	19	(	(	PUNCT
easat-264	78	20	also	also	ADV
easat-264	78	21	named	name	VERB
easat-264	78	22	precision	precision	NOUN
easat-264	78	23	medicine	medicine	NOUN
easat-264	78	24	)	)	PUNCT
easat-264	78	25	individualizes	individualize	VERB
easat-264	78	26	the	the	DET
easat-264	78	27	disease	disease	NOUN
easat-264	78	28	and	and	CCONJ
easat-264	78	29	consequently	consequently	ADV
easat-264	78	30	the	the	DET
easat-264	78	31	treatment	treatment	NOUN
easat-264	78	32	that	that	PRON
easat-264	78	33	must	must	AUX
easat-264	78	34	regulate	regulate	VERB
easat-264	78	35	it	it	PRON
easat-264	78	36	3	3	NUM
easat-264	78	37	.	.	PUNCT
easat-264	78	38	the	the	DET
easat-264	78	39	best	good	ADJ
easat-264	78	40	way	way	NOUN
easat-264	78	41	to	to	PART
easat-264	78	42	achieve	achieve	VERB
easat-264	78	43	this	this	DET
easat-264	78	44	goal	goal	NOUN
easat-264	78	45	is	be	AUX
easat-264	78	46	probably	probably	ADV
easat-264	78	47	to	to	PART
easat-264	78	48	use	use	VERB
easat-264	78	49	the	the	DET
easat-264	78	50	molecular	molecular	ADJ
easat-264	78	51	resources	resource	NOUN
easat-264	78	52	of	of	ADP
easat-264	78	53	the	the	DET
easat-264	78	54	cell	cell	NOUN
easat-264	78	55	itself	itself	PRON
easat-264	78	56	,	,	PUNCT
easat-264	78	57	and	and	CCONJ
easat-264	78	58	direct	direct	VERB
easat-264	78	59	them	they	PRON
easat-264	78	60	towards	towards	ADP
easat-264	78	61	a	a	DET
easat-264	78	62	return	return	NOUN
easat-264	78	63	to	to	ADP
easat-264	78	64	cellular	cellular	ADJ
easat-264	78	65	homeostasis	homeostasis	NOUN
easat-264	78	66	through	through	ADP
easat-264	78	67	a	a	DET
easat-264	78	68	regulatory	regulatory	ADJ
easat-264	78	69	treatment	treatment	NOUN
easat-264	78	70	.	.	PUNCT
easat-264	79	1	4	4	X
easat-264	79	2	.	.	X
easat-264	79	3	the	the	DET
easat-264	79	4	bi(g)med	bi(g)med	PROPN
easat-264	79	5	is	be	AUX
easat-264	79	6	suitable	suitable	ADJ
easat-264	79	7	for	for	ADP
easat-264	79	8	this	this	DET
easat-264	79	9	regulatory	regulatory	ADJ
easat-264	79	10	process	process	NOUN
easat-264	79	11	in	in	ADP
easat-264	79	12	the	the	DET
easat-264	79	13	form	form	NOUN
easat-264	79	14	of	of	ADP
easat-264	79	15	a	a	DET
easat-264	79	16	sublingual	sublingual	ADJ
easat-264	79	17	nanotherapy	nanotherapy	NOUN
easat-264	79	18	,	,	PUNCT
easat-264	79	19	whose	whose	DET
easat-264	79	20	efficiency	efficiency	NOUN
easat-264	79	21	is	be	AUX
easat-264	79	22	confirmed	confirm	VERB
easat-264	79	23	in	in	ADP
easat-264	79	24	very	very	ADV
easat-264	79	25	variable	variable	ADJ
easat-264	79	26	clinical	clinical	ADJ
easat-264	79	27	situations	situation	NOUN
easat-264	79	28	.	.	PUNCT
easat-264	80	1	abbreviations	abbreviation	NOUN
easat-264	80	2	:	:	PUNCT
easat-264	80	3	bi(g)med	bi(g)me	VERB
easat-264	80	4	-	-	PUNCT
easat-264	80	5	bio	bio	NOUN
easat-264	80	6	immune(g)ene	immune(g)ene	ADJ
easat-264	80	7	medicine	medicine	NOUN
easat-264	80	8	,	,	PUNCT
easat-264	80	9	pbcprimary	pbcprimary	ADJ
easat-264	80	10	biliary	biliary	ADJ
easat-264	80	11	cirrhosis	cirrhosis	NOUN
easat-264	80	12	,	,	PUNCT
easat-264	80	13	sscsystemic	sscsystemic	ADJ
easat-264	80	14	sclerosis	sclerosis	NOUN
easat-264	80	15	,	,	PUNCT
easat-264	80	16	ent	ent	PROPN
easat-264	80	17	infectionear	infectionear	PROPN
easat-264	80	18	,	,	PUNCT
easat-264	80	19	nose	nose	NOUN
easat-264	80	20	and	and	CCONJ
easat-264	80	21	throat	throat	NOUN
easat-264	80	22	infections	infection	NOUN
easat-264	80	23	.	.	PUNCT
easat-264	81	1	references	reference	NOUN
easat-264	81	2	[	[	X
easat-264	81	3	1	1	X
easat-264	81	4	]	]	PUNCT
easat-264	81	5	d.	d.	PROPN
easat-264	81	6	g.	g.	PROPN
easat-264	81	7	limbaugh	limbaugh	PROPN
easat-264	81	8	,	,	PUNCT
easat-264	81	9	"	"	PUNCT
easat-264	81	10	the	the	DET
easat-264	81	11	harm	harm	NOUN
easat-264	81	12	of	of	ADP
easat-264	81	13	medical	medical	ADJ
easat-264	81	14	disorder	disorder	NOUN
easat-264	81	15	as	as	ADP
easat-264	81	16	harm	harm	NOUN
easat-264	81	17	in	in	ADP
easat-264	81	18	the	the	DET
easat-264	81	19	damage	damage	NOUN
easat-264	81	20	sense	sense	NOUN
easat-264	81	21	,	,	PUNCT
easat-264	81	22	"	"	PUNCT
easat-264	81	23	theoretical	theoretical	ADJ
easat-264	81	24	medicine	medicine	NOUN
easat-264	81	25	and	and	CCONJ
easat-264	81	26	bioethics	bioethics	NOUN
easat-264	81	27	,	,	PUNCT
easat-264	81	28	vol	vol	NOUN
easat-264	81	29	.	.	PROPN
easat-264	81	30	40	40	NUM
easat-264	81	31	,	,	PUNCT
easat-264	81	32	no	no	INTJ
easat-264	81	33	.	.	NOUN
easat-264	81	34	1	1	NUM
easat-264	81	35	,	,	PUNCT
easat-264	81	36	pp	pp	ADJ
easat-264	81	37	.	.	PUNCT
easat-264	82	1	1	1	NUM
easat-264	82	2	-	-	SYM
easat-264	82	3	19	19	NUM
easat-264	82	4	,	,	PUNCT
easat-264	82	5	2019	2019	NUM
easat-264	82	6	.	.	PUNCT
easat-264	83	1	https://doi.org/10.1007/s11017-019-09483-y	https://doi.org/10.1007/s11017-019-09483-y	PROPN
easat-264	83	2	[	[	X
easat-264	83	3	2	2	NUM
easat-264	83	4	]	]	PUNCT
easat-264	83	5	d.	d.	PROPN
easat-264	83	6	destoumieux	destoumieux	PROPN
easat-264	83	7	-	-	PROPN
easat-264	83	8	garzón	garzón	PROPN
easat-264	83	9	et	et	PROPN
easat-264	83	10	al	al	PROPN
easat-264	83	11	.	.	PROPN
easat-264	83	12	,	,	PUNCT
easat-264	83	13	"	"	PUNCT
easat-264	83	14	the	the	DET
easat-264	83	15	one	one	NUM
easat-264	83	16	health	health	NOUN
easat-264	83	17	concept	concept	NOUN
easat-264	83	18	:	:	PUNCT
easat-264	83	19	10	10	NUM
easat-264	83	20	years	year	NOUN
easat-264	83	21	old	old	ADJ
easat-264	83	22	and	and	CCONJ
easat-264	83	23	a	a	DET
easat-264	83	24	long	long	ADJ
easat-264	83	25	road	road	NOUN
easat-264	83	26	ahead	ahead	ADV
easat-264	83	27	,	,	PUNCT
easat-264	83	28	"	"	PUNCT
easat-264	83	29	frontiers	frontier	NOUN
easat-264	83	30	in	in	ADP
easat-264	83	31	veterinary	veterinary	ADJ
easat-264	83	32	science	science	NOUN
easat-264	83	33	,	,	PUNCT
easat-264	83	34	vol	vol	NOUN
easat-264	83	35	.	.	PROPN
easat-264	83	36	5	5	NUM
easat-264	83	37	,	,	PUNCT
easat-264	83	38	p.	p.	NOUN
easat-264	83	39	14	14	NUM
easat-264	83	40	,	,	PUNCT
easat-264	83	41	2018	2018	NUM
easat-264	83	42	.	.	PUNCT
easat-264	84	1	https://doi.org/10.3389/fvets.2018.00014	https://doi.org/10.3389/fvets.2018.00014	PROPN
easat-264	85	1	[	[	X
easat-264	85	2	3	3	NUM
easat-264	85	3	]	]	PUNCT
easat-264	85	4	m.	m.	NOUN
easat-264	85	5	di	di	PROPN
easat-264	85	6	sanzo	sanzo	PROPN
easat-264	85	7	et	et	PROPN
easat-264	85	8	al	al	PROPN
easat-264	85	9	.	.	PROPN
easat-264	85	10	,	,	PUNCT
easat-264	85	11	"	"	PUNCT
easat-264	85	12	clinical	clinical	ADJ
easat-264	85	13	applications	application	NOUN
easat-264	85	14	of	of	ADP
easat-264	85	15	personalized	personalized	ADJ
easat-264	85	16	medicine	medicine	NOUN
easat-264	85	17	:	:	PUNCT
easat-264	85	18	a	a	DET
easat-264	85	19	new	new	ADJ
easat-264	85	20	paradigm	paradigm	NOUN
easat-264	85	21	and	and	CCONJ
easat-264	85	22	challenge	challenge	NOUN
easat-264	85	23	,	,	PUNCT
easat-264	85	24	"	"	PUNCT
easat-264	85	25	current	current	ADJ
easat-264	85	26	pharmaceutical	pharmaceutical	NOUN
easat-264	85	27	biotechnology	biotechnology	NOUN
easat-264	85	28	,	,	PUNCT
easat-264	85	29	vol	vol	NOUN
easat-264	85	30	.	.	PROPN
easat-264	85	31	18	18	NUM
easat-264	85	32	,	,	PUNCT
easat-264	85	33	no	no	INTJ
easat-264	85	34	.	.	NOUN
easat-264	85	35	3	3	NUM
easat-264	85	36	,	,	PUNCT
easat-264	85	37	pp	pp	ADJ
easat-264	85	38	.	.	PUNCT
easat-264	85	39	194	194	NUM
easat-264	85	40	-	-	SYM
easat-264	85	41	203	203	NUM
easat-264	85	42	,	,	PUNCT
easat-264	85	43	2017	2017	NUM
easat-264	85	44	.	.	PUNCT
easat-264	86	1	https://doi.org/10.2174/1389201018666170224105600	https://doi.org/10.2174/1389201018666170224105600	X
easat-264	87	1	[	[	X
easat-264	87	2	4	4	NUM
easat-264	87	3	]	]	PUNCT
easat-264	87	4	p.	p.	NOUN
easat-264	87	5	salari	salari	PROPN
easat-264	87	6	and	and	CCONJ
easat-264	87	7	b.	b.	PROPN
easat-264	87	8	larijani	larijani	PROPN
easat-264	87	9	,	,	PUNCT
easat-264	87	10	"	"	PUNCT
easat-264	87	11	ethical	ethical	ADJ
easat-264	87	12	issues	issue	NOUN
easat-264	87	13	surrounding	surround	VERB
easat-264	87	14	personalized	personalized	ADJ
easat-264	87	15	medicine	medicine	NOUN
easat-264	87	16	:	:	PUNCT
easat-264	87	17	a	a	DET
easat-264	87	18	literature	literature	NOUN
easat-264	87	19	review	review	NOUN
easat-264	87	20	"	"	PUNCT
easat-264	87	21	acta	acta	PROPN
easat-264	87	22	medica	medica	PROPN
easat-264	87	23	iranica	iranica	PROPN
easat-264	87	24	,	,	PUNCT
easat-264	87	25	vol	vol	NOUN
easat-264	87	26	.	.	PROPN
easat-264	88	1	55	55	NUM
easat-264	88	2	,	,	PUNCT
easat-264	88	3	no	no	INTJ
easat-264	88	4	.	.	NOUN
easat-264	88	5	3	3	NUM
easat-264	88	6	,	,	PUNCT
easat-264	88	7	pp	pp	ADJ
easat-264	88	8	.	.	PUNCT
easat-264	89	1	209	209	NUM
easat-264	89	2	-	-	SYM
easat-264	89	3	217	217	NUM
easat-264	89	4	,	,	PUNCT
easat-264	89	5	2017	2017	NUM
easat-264	89	6	.	.	PUNCT
easat-264	90	1	[	[	X
easat-264	90	2	5	5	NUM
easat-264	90	3	]	]	X
easat-264	90	4	j.-m	j.-m	NOUN
easat-264	90	5	.	.	PUNCT
easat-264	91	1	anaya	anaya	PROPN
easat-264	91	2	,	,	PUNCT
easat-264	91	3	c.	c.	PROPN
easat-264	91	4	duarte	duarte	PROPN
easat-264	91	5	-	-	PUNCT
easat-264	91	6	rey	rey	PROPN
easat-264	91	7	,	,	PUNCT
easat-264	91	8	j.	j.	PROPN
easat-264	91	9	c.	c.	PROPN
easat-264	91	10	sarmiento	sarmiento	PROPN
easat-264	91	11	-	-	PUNCT
easat-264	91	12	monroy	monroy	PROPN
easat-264	91	13	,	,	PUNCT
easat-264	91	14	d.	d.	PROPN
easat-264	91	15	bardey	bardey	PROPN
easat-264	91	16	,	,	PUNCT
easat-264	91	17	j.	j.	PROPN
easat-264	91	18	castiblanco	castiblanco	PROPN
easat-264	91	19	,	,	PUNCT
easat-264	91	20	and	and	CCONJ
easat-264	91	21	a.	a.	PROPN
easat-264	91	22	rojas	rojas	PROPN
easat-264	91	23	-	-	PUNCT
easat-264	91	24	villarraga	villarraga	NOUN
easat-264	91	25	,	,	PUNCT
easat-264	91	26	"	"	PUNCT
easat-264	91	27	personalized	personalized	ADJ
easat-264	91	28	medicine	medicine	NOUN
easat-264	91	29	.	.	PUNCT
easat-264	92	1	closing	close	VERB
easat-264	92	2	the	the	DET
easat-264	92	3	gap	gap	NOUN
easat-264	92	4	between	between	ADP
easat-264	92	5	knowledge	knowledge	NOUN
easat-264	92	6	and	and	CCONJ
easat-264	92	7	clinical	clinical	ADJ
easat-264	92	8	practice	practice	NOUN
easat-264	92	9	,	,	PUNCT
easat-264	92	10	"	"	PUNCT
easat-264	92	11	autoimmunity	autoimmunity	NOUN
easat-264	92	12	reviews	review	NOUN
easat-264	92	13	,	,	PUNCT
easat-264	92	14	vol	vol	NOUN
easat-264	92	15	.	.	PROPN
easat-264	92	16	15	15	NUM
easat-264	92	17	,	,	PUNCT
easat-264	92	18	no	no	INTJ
easat-264	92	19	.	.	NOUN
easat-264	92	20	8	8	NUM
easat-264	92	21	,	,	PUNCT
easat-264	92	22	pp	pp	ADJ
easat-264	92	23	.	.	PUNCT
easat-264	93	1	833	833	NUM
easat-264	93	2	-	-	SYM
easat-264	93	3	842	842	NUM
easat-264	93	4	,	,	PUNCT
easat-264	93	5	2016	2016	NUM
easat-264	93	6	.	.	PUNCT
easat-264	94	1	https://doi.org/10.1016/j.autrev.2016.06.005	https://doi.org/10.1016/j.autrev.2016.06.005	NUM
easat-264	95	1	[	[	X
easat-264	95	2	6	6	NUM
easat-264	95	3	]	]	PUNCT
easat-264	95	4	j.	j.	PROPN
easat-264	95	5	a.	a.	PROPN
easat-264	95	6	bengoechea	bengoechea	PROPN
easat-264	95	7	,	,	PUNCT
easat-264	95	8	"	"	PUNCT
easat-264	95	9	infection	infection	NOUN
easat-264	95	10	systems	system	NOUN
easat-264	95	11	biology	biology	NOUN
easat-264	95	12	:	:	PUNCT
easat-264	95	13	from	from	ADP
easat-264	95	14	reactive	reactive	NOUN
easat-264	95	15	to	to	ADP
easat-264	95	16	proactive	proactive	ADJ
easat-264	95	17	(	(	PUNCT
easat-264	95	18	p4	p4	ADJ
easat-264	95	19	)	)	PUNCT
easat-264	95	20	medicine	medicine	NOUN
easat-264	95	21	,	,	PUNCT
easat-264	95	22	"	"	PUNCT
easat-264	95	23	international	international	ADJ
easat-264	95	24	microbiology	microbiology	NOUN
easat-264	95	25	,	,	PUNCT
easat-264	95	26	vol	vol	NOUN
easat-264	95	27	.	.	PROPN
easat-264	95	28	15	15	NUM
easat-264	95	29	,	,	PUNCT
easat-264	95	30	no	no	INTJ
easat-264	95	31	.	.	NOUN
easat-264	95	32	2	2	NUM
easat-264	95	33	,	,	PUNCT
easat-264	95	34	pp	pp	ADJ
easat-264	95	35	.	.	PUNCT
easat-264	96	1	55	55	NUM
easat-264	96	2	-	-	SYM
easat-264	96	3	60	60	NUM
easat-264	96	4	,	,	PUNCT
easat-264	96	5	2012	2012	NUM
easat-264	96	6	.	.	PUNCT
easat-264	97	1	[	[	X
easat-264	97	2	7	7	X
easat-264	97	3	]	]	PUNCT
easat-264	97	4	m.	m.	NOUN
easat-264	97	5	sagner	sagner	PROPN
easat-264	97	6	et	et	PROPN
easat-264	97	7	al	al	PROPN
easat-264	97	8	.	.	PROPN
easat-264	97	9	,	,	PUNCT
easat-264	97	10	"	"	PUNCT
easat-264	97	11	the	the	DET
easat-264	97	12	p4	p4	ADJ
easat-264	97	13	health	health	NOUN
easat-264	97	14	spectrum	spectrum	NOUN
easat-264	97	15	–	–	PUNCT
easat-264	97	16	a	a	DET
easat-264	97	17	predictive	predictive	ADJ
easat-264	97	18	,	,	PUNCT
easat-264	97	19	preventive	preventive	ADJ
easat-264	97	20	,	,	PUNCT
easat-264	97	21	personalized	personalized	ADJ
easat-264	97	22	and	and	CCONJ
easat-264	97	23	participatory	participatory	ADJ
easat-264	97	24	continuum	continuum	NOUN
easat-264	97	25	for	for	ADP
easat-264	97	26	promoting	promote	VERB
easat-264	97	27	healthspan	healthspan	NOUN
easat-264	97	28	,	,	PUNCT
easat-264	97	29	"	"	PUNCT
easat-264	97	30	progress	progress	NOUN
easat-264	97	31	in	in	ADP
easat-264	97	32	cardiovascular	cardiovascular	ADJ
easat-264	97	33	diseases	disease	NOUN
easat-264	97	34	,	,	PUNCT
easat-264	97	35	vol	vol	NOUN
easat-264	97	36	.	.	PROPN
easat-264	97	37	59	59	NUM
easat-264	97	38	,	,	PUNCT
easat-264	97	39	no	no	INTJ
easat-264	97	40	.	.	NOUN
easat-264	97	41	5	5	NUM
easat-264	97	42	,	,	PUNCT
easat-264	97	43	pp	pp	ADJ
easat-264	97	44	.	.	PUNCT
easat-264	97	45	506	506	NUM
easat-264	97	46	-	-	SYM
easat-264	97	47	521	521	NUM
easat-264	97	48	,	,	PUNCT
easat-264	97	49	2017	2017	NUM
easat-264	97	50	.	.	PUNCT
easat-264	98	1	https://doi.org/10.1097/pp9.0000000000000002	https://doi.org/10.1097/pp9.0000000000000002	NOUN
easat-264	99	1	[	[	X
easat-264	99	2	8	8	NUM
easat-264	99	3	]	]	PUNCT
easat-264	99	4	j.	j.	PROPN
easat-264	99	5	r.	r.	PROPN
easat-264	99	6	heath	heath	PROPN
easat-264	99	7	,	,	PUNCT
easat-264	99	8	m.	m.	PROPN
easat-264	99	9	e.	e.	PROPN
easat-264	99	10	phelps	phelps	PROPN
easat-264	99	11	,	,	PUNCT
easat-264	99	12	and	and	CCONJ
easat-264	99	13	l.	l.	PROPN
easat-264	99	14	hood	hood	PROPN
easat-264	99	15	,	,	PUNCT
easat-264	99	16	"	"	PUNCT
easat-264	99	17	nano	nano	NOUN
easat-264	99	18	systems	system	NOUN
easat-264	99	19	biology	biology	NOUN
easat-264	99	20	,	,	PUNCT
easat-264	99	21	"	"	PUNCT
easat-264	99	22	molecular	molecular	ADJ
easat-264	99	23	imaging	imaging	NOUN
easat-264	99	24	&	&	CCONJ
easat-264	99	25	biology	biology	NOUN
easat-264	99	26	,	,	PUNCT
easat-264	99	27	vol	vol	NOUN
easat-264	99	28	.	.	PROPN
easat-264	99	29	5	5	NUM
easat-264	99	30	,	,	PUNCT
easat-264	99	31	no	no	INTJ
easat-264	99	32	.	.	NOUN
easat-264	99	33	5	5	NUM
easat-264	99	34	,	,	PUNCT
easat-264	99	35	pp	pp	ADJ
easat-264	99	36	.	.	PUNCT
easat-264	100	1	312325	312325	NUM
easat-264	100	2	,	,	PUNCT
easat-264	100	3	2003	2003	NUM
easat-264	100	4	.	.	PUNCT
easat-264	101	1	[	[	X
easat-264	101	2	9	9	NUM
easat-264	101	3	]	]	SYM
easat-264	101	4	i.	i.	PROPN
easat-264	101	5	r.	r.	PROPN
easat-264	101	6	könig	könig	PROPN
easat-264	101	7	,	,	PUNCT
easat-264	101	8	o.	o.	PROPN
easat-264	101	9	fuchs	fuchs	PROPN
easat-264	101	10	,	,	PUNCT
easat-264	101	11	g.	g.	PROPN
easat-264	101	12	hansen	hansen	PROPN
easat-264	101	13	,	,	PUNCT
easat-264	101	14	e.	e.	PROPN
easat-264	101	15	von	von	PROPN
easat-264	101	16	mutius	mutius	PROPN
easat-264	101	17	,	,	PUNCT
easat-264	101	18	and	and	CCONJ
easat-264	101	19	m.	m.	NOUN
easat-264	101	20	v.	v.	ADP
easat-264	101	21	kopp	kopp	PROPN
easat-264	101	22	,	,	PUNCT
easat-264	101	23	"	"	PUNCT
easat-264	101	24	what	what	PRON
easat-264	101	25	is	be	AUX
easat-264	101	26	precision	precision	NOUN
easat-264	101	27	medicine	medicine	NOUN
easat-264	101	28	?	?	PUNCT
easat-264	101	29	,	,	PUNCT
easat-264	101	30	"	"	PUNCT
easat-264	101	31	european	european	ADJ
easat-264	101	32	respiratory	respiratory	ADJ
easat-264	101	33	journal	journal	NOUN
easat-264	101	34	,	,	PUNCT
easat-264	101	35	vol	vol	NOUN
easat-264	101	36	.	.	PROPN
easat-264	101	37	50	50	NUM
easat-264	101	38	,	,	PUNCT
easat-264	101	39	no	no	INTJ
easat-264	101	40	.	.	NOUN
easat-264	101	41	4	4	NUM
easat-264	101	42	,	,	PUNCT
easat-264	101	43	pp	pp	ADJ
easat-264	101	44	.	.	PUNCT
easat-264	102	1	1	1	NUM
easat-264	102	2	-	-	SYM
easat-264	102	3	12	12	NUM
easat-264	102	4	,	,	PUNCT
easat-264	102	5	2017	2017	NUM
easat-264	102	6	.	.	PUNCT
easat-264	102	7	https://doi.org/10.1183/13993003.00391-2017	https://doi.org/10.1183/13993003.00391-2017	X
easat-264	103	1	[	[	X
easat-264	103	2	10	10	NUM
easat-264	103	3	]	]	X
easat-264	103	4	g.	g.	PROPN
easat-264	103	5	s.	s.	PROPN
easat-264	103	6	ginsburg	ginsburg	PROPN
easat-264	103	7	and	and	CCONJ
easat-264	103	8	k.	k.	PROPN
easat-264	103	9	a.	a.	PROPN
easat-264	103	10	phillips	phillips	PROPN
easat-264	103	11	,	,	PUNCT
easat-264	103	12	"	"	PUNCT
easat-264	103	13	precision	precision	NOUN
easat-264	103	14	medicine	medicine	NOUN
easat-264	103	15	:	:	PUNCT
easat-264	103	16	from	from	ADP
easat-264	103	17	science	science	NOUN
easat-264	103	18	to	to	ADP
easat-264	103	19	value	value	NOUN
easat-264	103	20	,	,	PUNCT
easat-264	103	21	"	"	PUNCT
easat-264	103	22	health	health	NOUN
easat-264	103	23	affairs	affair	NOUN
easat-264	103	24	,	,	PUNCT
easat-264	103	25	vol	vol	NOUN
easat-264	103	26	.	.	PROPN
easat-264	104	1	37	37	NUM
easat-264	104	2	,	,	PUNCT
easat-264	104	3	no	no	INTJ
easat-264	104	4	.	.	NOUN
easat-264	104	5	5	5	NUM
easat-264	104	6	,	,	PUNCT
easat-264	104	7	pp	pp	ADJ
easat-264	104	8	.	.	PUNCT
easat-264	105	1	694701	694701	NUM
easat-264	105	2	,	,	PUNCT
easat-264	105	3	2018	2018	NUM
easat-264	105	4	.	.	PUNCT
easat-264	106	1	https://doi.org/10.1377/hlthaff.2017.1624	https://doi.org/10.1377/hlthaff.2017.1624	PRON
easat-264	106	2	[	[	X
easat-264	106	3	11	11	NUM
easat-264	106	4	]	]	X
easat-264	106	5	g.	g.	PROPN
easat-264	106	6	r.	r.	PROPN
easat-264	106	7	gameiro	gameiro	PROPN
easat-264	106	8	,	,	PUNCT
easat-264	106	9	v.	v.	PROPN
easat-264	106	10	sinkunas	sinkunas	PROPN
easat-264	106	11	,	,	PUNCT
easat-264	106	12	g.	g.	PROPN
easat-264	106	13	r.	r.	PROPN
easat-264	106	14	liguori	liguori	PROPN
easat-264	106	15	,	,	PUNCT
easat-264	106	16	and	and	CCONJ
easat-264	106	17	j.	j.	PROPN
easat-264	106	18	o.	o.	PROPN
easat-264	106	19	c.	c.	PROPN
easat-264	106	20	auler	auler	PROPN
easat-264	106	21	-	-	PUNCT
easat-264	106	22	júnior	júnior	NOUN
easat-264	106	23	,	,	PUNCT
easat-264	106	24	"	"	PUNCT
easat-264	106	25	precision	precision	NOUN
easat-264	106	26	medicine	medicine	NOUN
easat-264	106	27	:	:	PUNCT
easat-264	106	28	changing	change	VERB
easat-264	106	29	the	the	DET
easat-264	106	30	way	way	NOUN
easat-264	106	31	we	we	PRON
easat-264	106	32	think	think	VERB
easat-264	106	33	about	about	ADP
easat-264	106	34	healthcare	healthcare	NOUN
easat-264	106	35	,	,	PUNCT
easat-264	106	36	"	"	PUNCT
easat-264	106	37	clinics	clinic	NOUN
easat-264	106	38	,	,	PUNCT
easat-264	106	39	vol	vol	NOUN
easat-264	106	40	.	.	PROPN
easat-264	106	41	73	73	NUM
easat-264	106	42	,	,	PUNCT
easat-264	106	43	p.	p.	NOUN
easat-264	106	44	e723	e723	PROPN
easat-264	106	45	,	,	PUNCT
easat-264	106	46	2018	2018	NUM
easat-264	106	47	.	.	PUNCT
easat-264	106	48	https://doi.org/10.6061/clinics/2017/e723	https://doi.org/10.6061/clinics/2017/e723	PROPN
easat-264	107	1	[	[	X
easat-264	107	2	12	12	NUM
easat-264	107	3	]	]	PUNCT
easat-264	107	4	k.	k.	PROPN
easat-264	107	5	wang	wang	PROPN
easat-264	107	6	,	,	PUNCT
easat-264	107	7	i.	i.	PROPN
easat-264	107	8	lee	lee	PROPN
easat-264	107	9	,	,	PUNCT
easat-264	107	10	g.	g.	PROPN
easat-264	107	11	carlson	carlson	PROPN
easat-264	107	12	,	,	PUNCT
easat-264	107	13	l.	l.	PROPN
easat-264	107	14	hood	hood	PROPN
easat-264	107	15	,	,	PUNCT
easat-264	107	16	and	and	CCONJ
easat-264	107	17	d.	d.	PROPN
easat-264	107	18	galas	gala	NOUN
easat-264	107	19	,	,	PUNCT
easat-264	107	20	"	"	PUNCT
easat-264	107	21	systems	system	NOUN
easat-264	107	22	biology	biology	NOUN
easat-264	107	23	and	and	CCONJ
easat-264	107	24	the	the	DET
easat-264	107	25	discovery	discovery	NOUN
easat-264	107	26	of	of	ADP
easat-264	107	27	diagnostic	diagnostic	ADJ
easat-264	107	28	biomarkers	biomarker	NOUN
easat-264	107	29	,	,	PUNCT
easat-264	107	30	"	"	PUNCT
easat-264	107	31	disease	disease	NOUN
easat-264	107	32	markers	marker	NOUN
easat-264	107	33	,	,	PUNCT
easat-264	107	34	vol	vol	NOUN
easat-264	107	35	.	.	PROPN
easat-264	107	36	28	28	NUM
easat-264	107	37	,	,	PUNCT
easat-264	107	38	no	no	INTJ
easat-264	107	39	.	.	NOUN
easat-264	107	40	4	4	NUM
easat-264	107	41	,	,	PUNCT
easat-264	107	42	pp	pp	ADJ
easat-264	107	43	.	.	PUNCT
easat-264	108	1	199	199	NUM
easat-264	108	2	-	-	SYM
easat-264	108	3	207	207	NUM
easat-264	108	4	,	,	PUNCT
easat-264	108	5	2010	2010	NUM
easat-264	108	6	.	.	PUNCT
easat-264	109	1	https://doi.org/10.1155/2010/130861	https://doi.org/10.1155/2010/130861	PUNCT
easat-264	110	1	[	[	X
easat-264	110	2	13	13	NUM
easat-264	110	3	]	]	PUNCT
easat-264	110	4	l.	l.	PROPN
easat-264	110	5	caberlotto	caberlotto	PROPN
easat-264	110	6	and	and	CCONJ
easat-264	110	7	m.	m.	PROPN
easat-264	110	8	lauria	lauria	PROPN
easat-264	110	9	,	,	PUNCT
easat-264	110	10	"	"	PUNCT
easat-264	110	11	systems	system	NOUN
easat-264	110	12	biology	biology	NOUN
easat-264	110	13	meets	meet	VERB
easat-264	110	14	-	-	PUNCT
easat-264	110	15	omic	omic	ADJ
easat-264	110	16	technologies	technology	NOUN
easat-264	110	17	:	:	PUNCT
easat-264	110	18	novel	novel	ADJ
easat-264	110	19	approaches	approach	NOUN
easat-264	110	20	to	to	PART
easat-264	110	21	biomarker	biomarker	VERB
easat-264	110	22	discovery	discovery	NOUN
easat-264	110	23	and	and	CCONJ
easat-264	110	24	companion	companion	NOUN
easat-264	110	25	diagnostic	diagnostic	ADJ
easat-264	110	26	development	development	NOUN
easat-264	110	27	,	,	PUNCT
easat-264	110	28	"	"	PUNCT
easat-264	110	29	expert	expert	NOUN
easat-264	110	30	review	review	NOUN
easat-264	110	31	of	of	ADP
easat-264	110	32	molecular	molecular	ADJ
easat-264	110	33	diagnostics	diagnostic	NOUN
easat-264	110	34	,	,	PUNCT
easat-264	110	35	vol	vol	NOUN
easat-264	110	36	.	.	PROPN
easat-264	110	37	15	15	NUM
easat-264	110	38	,	,	PUNCT
easat-264	110	39	no	no	INTJ
easat-264	110	40	.	.	NOUN
easat-264	110	41	2	2	NUM
easat-264	110	42	,	,	PUNCT
easat-264	110	43	pp	pp	ADJ
easat-264	110	44	.	.	PUNCT
easat-264	111	1	255	255	NUM
easat-264	111	2	-	-	SYM
easat-264	111	3	265	265	NUM
easat-264	111	4	,	,	PUNCT
easat-264	111	5	2015	2015	NUM
easat-264	111	6	.	.	PUNCT
easat-264	111	7	https://doi.org/10.1586/14737159.2015.975214	https://doi.org/10.1586/14737159.2015.975214	PUNCT
easat-264	112	1	[	[	X
easat-264	112	2	14	14	NUM
easat-264	112	3	]	]	X
easat-264	112	4	t.	t.	PROPN
easat-264	112	5	szczepański	szczepański	PROPN
easat-264	112	6	,	,	PUNCT
easat-264	112	7	v.	v.	PROPN
easat-264	112	8	h.	h.	PROPN
easat-264	112	9	van	van	PROPN
easat-264	112	10	der	der	PROPN
easat-264	112	11	velden	velden	PROPN
easat-264	112	12	,	,	PUNCT
easat-264	112	13	and	and	CCONJ
easat-264	112	14	j.	j.	PROPN
easat-264	112	15	j.	j.	PROPN
easat-264	112	16	van	van	PROPN
easat-264	112	17	dongen	dongen	PROPN
easat-264	112	18	,	,	PUNCT
easat-264	112	19	"	"	PUNCT
easat-264	112	20	flow	flow	NOUN
easat-264	112	21	-	-	PUNCT
easat-264	112	22	cytometric	cytometric	ADJ
easat-264	112	23	immunophenotyping	immunophenotyping	NOUN
easat-264	112	24	of	of	ADP
easat-264	112	25	normal	normal	ADJ
easat-264	112	26	and	and	CCONJ
easat-264	112	27	malignant	malignant	ADJ
easat-264	112	28	lymphocytes	lymphocyte	NOUN
easat-264	112	29	,	,	PUNCT
easat-264	112	30	"	"	PUNCT
easat-264	112	31	clinical	clinical	ADJ
easat-264	112	32	chemistry	chemistry	NOUN
easat-264	112	33	and	and	CCONJ
easat-264	112	34	laboratory	laboratory	NOUN
easat-264	112	35	medicine	medicine	NOUN
easat-264	112	36	,	,	PUNCT
easat-264	112	37	vol	vol	NOUN
easat-264	112	38	.	.	PROPN
easat-264	112	39	44	44	NUM
easat-264	112	40	,	,	PUNCT
easat-264	112	41	no	no	INTJ
easat-264	112	42	.	.	NOUN
easat-264	112	43	7	7	NUM
easat-264	112	44	,	,	PUNCT
easat-264	112	45	pp	pp	ADJ
easat-264	112	46	.	.	PUNCT
easat-264	113	1	775	775	NUM
easat-264	113	2	-	-	SYM
easat-264	113	3	796	796	NUM
easat-264	113	4	,	,	PUNCT
easat-264	113	5	2006	2006	NUM
easat-264	113	6	.	.	PUNCT
easat-264	114	1	https://doi.org/10.1515/cclm.2006.146	https://doi.org/10.1515/cclm.2006.146	PROPN
easat-264	114	2	[	[	X
easat-264	114	3	15	15	NUM
easat-264	114	4	]	]	X
easat-264	114	5	j.	j.	PROPN
easat-264	114	6	dupond	dupond	PROPN
easat-264	114	7	,	,	PUNCT
easat-264	114	8	h.	h.	PROPN
easat-264	114	9	gil	gil	PROPN
easat-264	114	10	,	,	PUNCT
easat-264	114	11	p.	p.	NOUN
easat-264	114	12	giraudet	giraudet	NOUN
easat-264	114	13	,	,	PUNCT
easat-264	114	14	r.	r.	PROPN
easat-264	114	15	gibey	gibey	PROPN
easat-264	114	16	,	,	PUNCT
easat-264	114	17	h.	h.	PROPN
easat-264	114	18	desmurs	desmurs	PROPN
easat-264	114	19	,	,	PUNCT
easat-264	114	20	and	and	CCONJ
easat-264	114	21	b.	b.	PROPN
easat-264	114	22	de	de	X
easat-264	114	23	wazieres	wazieres	PROPN
easat-264	114	24	,	,	PUNCT
easat-264	114	25	"	"	PUNCT
easat-264	114	26	interest	interest	NOUN
easat-264	114	27	of	of	ADP
easat-264	114	28	the	the	DET
easat-264	114	29	protein	protein	NOUN
easat-264	114	30	profile	profile	NOUN
easat-264	114	31	in	in	ADP
easat-264	114	32	unexplained	unexplained	ADJ
easat-264	114	33	inflammatory	inflammatory	ADJ
easat-264	114	34	syndromes	syndrome	NOUN
easat-264	114	35	,	,	PUNCT
easat-264	114	36	"	"	PUNCT
easat-264	114	37	la	la	X
easat-264	114	38	revue	revue	X
easat-264	114	39	de	de	X
easat-264	114	40	médecine	médecine	NOUN
easat-264	114	41	interne	interne	NOUN
easat-264	114	42	,	,	PUNCT
easat-264	114	43	vol	vol	NOUN
easat-264	114	44	.	.	PROPN
easat-264	114	45	18	18	NUM
easat-264	114	46	,	,	PUNCT
easat-264	114	47	no	no	INTJ
easat-264	114	48	.	.	NOUN
easat-264	114	49	5	5	NUM
easat-264	114	50	,	,	PUNCT
easat-264	114	51	pp	pp	ADJ
easat-264	114	52	.	.	PUNCT
easat-264	114	53	367	367	NUM
easat-264	114	54	-	-	SYM
easat-264	114	55	372	372	NUM
easat-264	114	56	,	,	PUNCT
easat-264	114	57	1997	1997	NUM
easat-264	114	58	.	.	PUNCT
easat-264	115	1	https://doi.org/10.1016/s0248-8663(97)80931-9	https://doi.org/10.1016/s0248-8663(97)80931-9	PROPN
easat-264	116	1	[	[	X
easat-264	116	2	16	16	NUM
easat-264	116	3	]	]	PUNCT
easat-264	116	4	s.	s.	PROPN
easat-264	116	5	bunyavanich	bunyavanich	PROPN
easat-264	116	6	and	and	CCONJ
easat-264	116	7	e.	e.	PROPN
easat-264	116	8	e.	e.	PROPN
easat-264	116	9	schadt	schadt	PROPN
easat-264	116	10	,	,	PUNCT
easat-264	116	11	"	"	PUNCT
easat-264	116	12	systems	system	NOUN
easat-264	116	13	biology	biology	NOUN
easat-264	116	14	of	of	ADP
easat-264	116	15	asthma	asthma	NOUN
easat-264	116	16	and	and	CCONJ
easat-264	116	17	allergic	allergic	ADJ
easat-264	116	18	diseases	disease	NOUN
easat-264	116	19	:	:	PUNCT
easat-264	116	20	a	a	DET
easat-264	116	21	multiscale	multiscale	ADJ
easat-264	116	22	approach	approach	NOUN
easat-264	116	23	,	,	PUNCT
easat-264	116	24	"	"	PUNCT
easat-264	116	25	journal	journal	NOUN
easat-264	116	26	of	of	ADP
easat-264	116	27	allergy	allergy	NOUN
easat-264	116	28	and	and	CCONJ
easat-264	116	29	clinical	clinical	ADJ
easat-264	116	30	immunology	immunology	NOUN
easat-264	116	31	,	,	PUNCT
easat-264	116	32	vol	vol	NOUN
easat-264	116	33	.	.	PROPN
easat-264	116	34	135	135	NUM
easat-264	116	35	,	,	PUNCT
easat-264	116	36	no	no	INTJ
easat-264	116	37	.	.	NOUN
easat-264	116	38	1	1	NUM
easat-264	116	39	,	,	PUNCT
easat-264	116	40	pp	pp	ADJ
easat-264	116	41	.	.	PUNCT
easat-264	117	1	31	31	NUM
easat-264	117	2	-	-	SYM
easat-264	117	3	42	42	NUM
easat-264	117	4	,	,	PUNCT
easat-264	117	5	2015	2015	NUM
easat-264	117	6	.	.	PUNCT
easat-264	118	1	https://doi.org/10.1016/j.jaci.2014.10.015	https://doi.org/10.1016/j.jaci.2014.10.015	NOUN
easat-264	119	1	[	[	X
easat-264	119	2	17	17	NUM
easat-264	119	3	]	]	X
easat-264	119	4	s.	s.	PROPN
easat-264	119	5	ur	ur	PROPN
easat-264	119	6	-	-	PROPN
easat-264	119	7	rehman	rehman	PROPN
easat-264	119	8	,	,	PUNCT
easat-264	119	9	z.	z.	PROPN
easat-264	119	10	mushtaq	mushtaq	PROPN
easat-264	119	11	,	,	PUNCT
easat-264	119	12	t.	t.	PROPN
easat-264	119	13	zahoor	zahoor	PROPN
easat-264	119	14	,	,	PUNCT
easat-264	119	15	a.	a.	PROPN
easat-264	119	16	jamil	jamil	PROPN
easat-264	119	17	,	,	PUNCT
easat-264	119	18	and	and	CCONJ
easat-264	119	19	m.	m.	PROPN
easat-264	119	20	a.	a.	PROPN
easat-264	119	21	murtaza	murtaza	PROPN
easat-264	119	22	,	,	PUNCT
easat-264	119	23	"	"	PUNCT
easat-264	119	24	xylitol	xylitol	NOUN
easat-264	119	25	:	:	PUNCT
easat-264	119	26	a	a	DET
easat-264	119	27	review	review	NOUN
easat-264	119	28	on	on	ADP
easat-264	119	29	bioproduction	bioproduction	NOUN
easat-264	119	30	,	,	PUNCT
easat-264	119	31	application	application	NOUN
easat-264	119	32	,	,	PUNCT
easat-264	119	33	health	health	NOUN
easat-264	119	34	benefits	benefit	NOUN
easat-264	119	35	,	,	PUNCT
easat-264	119	36	and	and	CCONJ
easat-264	119	37	related	related	ADJ
easat-264	119	38	safety	safety	NOUN
easat-264	119	39	issues	issue	NOUN
easat-264	119	40	,	,	PUNCT
easat-264	119	41	"	"	PUNCT
easat-264	119	42	critical	critical	ADJ
easat-264	119	43	reviews	review	NOUN
easat-264	119	44	in	in	ADP
easat-264	119	45	food	food	NOUN
easat-264	119	46	science	science	NOUN
easat-264	119	47	and	and	CCONJ
easat-264	119	48	nutrition	nutrition	NOUN
easat-264	119	49	,	,	PUNCT
easat-264	119	50	vol	vol	NOUN
easat-264	119	51	.	.	PROPN
easat-264	120	1	55	55	NUM
easat-264	120	2	,	,	PUNCT
easat-264	120	3	no	no	INTJ
easat-264	120	4	.	.	NOUN
easat-264	120	5	11	11	NUM
easat-264	120	6	,	,	PUNCT
easat-264	120	7	pp	pp	ADJ
easat-264	120	8	.	.	PUNCT
easat-264	121	1	1514	1514	NUM
easat-264	121	2	-	-	SYM
easat-264	121	3	1528	1528	NUM
easat-264	121	4	,	,	PUNCT
easat-264	121	5	2015	2015	NUM
easat-264	121	6	.	.	PUNCT
easat-264	122	1	https://doi.org/10.1080/10408398.2012.702288	https://doi.org/10.1080/10408398.2012.702288	PROPN
easat-264	122	2	[	[	X
easat-264	122	3	18	18	NUM
easat-264	122	4	]	]	X
easat-264	122	5	d.	d.	PROPN
easat-264	122	6	a.	a.	PROPN
easat-264	122	7	muller	muller	PROPN
easat-264	122	8	et	et	PROPN
easat-264	122	9	al	al	PROPN
easat-264	122	10	.	.	PROPN
easat-264	122	11	,	,	PUNCT
easat-264	122	12	"	"	PUNCT
easat-264	122	13	high	high	ADJ
easat-264	122	14	-	-	PUNCT
easat-264	122	15	density	density	NOUN
easat-264	122	16	microprojection	microprojection	NOUN
easat-264	122	17	array	array	NOUN
easat-264	122	18	delivery	delivery	NOUN
easat-264	122	19	to	to	PART
easat-264	122	20	rat	rat	VERB
easat-264	122	21	skin	skin	NOUN
easat-264	122	22	of	of	ADP
easat-264	122	23	low	low	ADJ
easat-264	122	24	doses	dose	NOUN
easat-264	122	25	of	of	ADP
easat-264	122	26	trivalent	trivalent	NOUN
easat-264	122	27	inactivated	inactivate	VERB
easat-264	122	28	poliovirus	poliovirus	NOUN
easat-264	122	29	vaccine	vaccine	NOUN
easat-264	122	30	elicits	elicit	VERB
easat-264	122	31	potent	potent	ADJ
easat-264	122	32	neutralising	neutralise	VERB
easat-264	122	33	antibody	antibody	NOUN
easat-264	122	34	responses	response	NOUN
easat-264	122	35	,	,	PUNCT
easat-264	122	36	"	"	PUNCT
easat-264	122	37	scientific	scientific	ADJ
easat-264	122	38	reports	report	NOUN
easat-264	122	39	,	,	PUNCT
easat-264	122	40	vol	vol	NOUN
easat-264	122	41	.	.	PROPN
easat-264	122	42	7	7	NUM
easat-264	122	43	,	,	PUNCT
easat-264	122	44	no	no	INTJ
easat-264	122	45	.	.	NOUN
easat-264	122	46	1	1	NUM
easat-264	122	47	,	,	PUNCT
easat-264	122	48	p.	p.	NOUN
easat-264	122	49	12644	12644	NUM
easat-264	122	50	,	,	PUNCT
easat-264	122	51	2017	2017	NUM
easat-264	122	52	.	.	PUNCT
easat-264	123	1	https://doi.org/10.1038/s41598-017-13011-0	https://doi.org/10.1038/s41598-017-13011-0	NUM
easat-264	123	2	[	[	X
easat-264	123	3	19	19	NUM
easat-264	123	4	]	]	PUNCT
easat-264	123	5	m.	m.	NOUN
easat-264	123	6	marzotto	marzotto	NOUN
easat-264	123	7	,	,	PUNCT
easat-264	123	8	d.	d.	PROPN
easat-264	123	9	olioso	olioso	PROPN
easat-264	123	10	,	,	PUNCT
easat-264	123	11	m.	m.	NOUN
easat-264	123	12	brizzi	brizzi	NOUN
easat-264	123	13	,	,	PUNCT
easat-264	123	14	p.	p.	NOUN
easat-264	123	15	tononi	tononi	NOUN
easat-264	123	16	,	,	PUNCT
easat-264	123	17	m.	m.	NOUN
easat-264	123	18	cristofoletti	cristofoletti	NOUN
easat-264	123	19	,	,	PUNCT
easat-264	123	20	and	and	CCONJ
easat-264	123	21	p.	p.	NOUN
easat-264	123	22	bellavite	bellavite	NOUN
easat-264	123	23	,	,	PUNCT
easat-264	123	24	"	"	PUNCT
easat-264	123	25	extreme	extreme	ADJ
easat-264	123	26	sensitivity	sensitivity	NOUN
easat-264	123	27	of	of	ADP
easat-264	123	28	gene	gene	NOUN
easat-264	123	29	expression	expression	NOUN
easat-264	123	30	in	in	ADP
easat-264	123	31	human	human	PROPN
easat-264	123	32	sh	sh	PROPN
easat-264	123	33	-	-	PUNCT
easat-264	123	34	sy5y	sy5y	PROPN
easat-264	123	35	neurocytes	neurocyte	NOUN
easat-264	123	36	to	to	ADP
easat-264	123	37	ultra	ultra	ADJ
easat-264	123	38	-	-	ADJ
easat-264	123	39	low	low	ADJ
easat-264	123	40	doses	dose	NOUN
easat-264	123	41	of	of	ADP
easat-264	123	42	gelsemium	gelsemium	NOUN
easat-264	123	43	sempervirens	semperviren	NOUN
easat-264	123	44	,	,	PUNCT
easat-264	123	45	"	"	PUNCT
easat-264	123	46	bmc	bmc	X
easat-264	123	47	complementary	complementary	ADJ
easat-264	123	48	and	and	CCONJ
easat-264	123	49	alternative	alternative	ADJ
easat-264	123	50	medicine	medicine	NOUN
easat-264	123	51	,	,	PUNCT
easat-264	123	52	vol	vol	NOUN
easat-264	123	53	.	.	PROPN
easat-264	124	1	14	14	NUM
easat-264	124	2	,	,	PUNCT
easat-264	124	3	no	no	INTJ
easat-264	124	4	.	.	NOUN
easat-264	124	5	1	1	NUM
easat-264	124	6	,	,	PUNCT
easat-264	124	7	pp	pp	ADJ
easat-264	124	8	.	.	PUNCT
easat-264	125	1	1	1	NUM
easat-264	125	2	-	-	SYM
easat-264	125	3	20	20	NUM
easat-264	125	4	,	,	PUNCT
easat-264	125	5	2014	2014	NUM
easat-264	125	6	.	.	PUNCT
easat-264	126	1	[	[	X
easat-264	126	2	20	20	NUM
easat-264	126	3	]	]	X
easat-264	126	4	d.	d.	PROPN
easat-264	126	5	olioso	olioso	PROPN
easat-264	126	6	,	,	PUNCT
easat-264	126	7	m.	m.	NOUN
easat-264	126	8	marzotto	marzotto	NOUN
easat-264	126	9	,	,	PUNCT
easat-264	126	10	e.	e.	PROPN
easat-264	126	11	moratti	moratti	PROPN
easat-264	126	12	,	,	PUNCT
easat-264	126	13	m.	m.	NOUN
easat-264	126	14	brizzi	brizzi	NOUN
easat-264	126	15	,	,	PUNCT
easat-264	126	16	and	and	CCONJ
easat-264	126	17	p.	p.	NOUN
easat-264	126	18	bellavite	bellavite	NOUN
easat-264	126	19	,	,	PUNCT
easat-264	126	20	"	"	PUNCT
easat-264	126	21	effects	effect	NOUN
easat-264	126	22	of	of	ADP
easat-264	126	23	gelsemium	gelsemium	NOUN
easat-264	126	24	sempervirens	semperviren	NOUN
easat-264	126	25	l.	l.	PROPN
easat-264	126	26	on	on	ADP
easat-264	126	27	pathwayfocused	pathwayfocuse	VERB
easat-264	126	28	gene	gene	NOUN
easat-264	126	29	expression	expression	NOUN
easat-264	126	30	profiling	profiling	NOUN
easat-264	126	31	in	in	ADP
easat-264	126	32	neuronal	neuronal	ADJ
easat-264	126	33	cells	cell	NOUN
easat-264	126	34	,	,	PUNCT
easat-264	126	35	"	"	PUNCT
easat-264	126	36	journal	journal	NOUN
easat-264	126	37	of	of	ADP
easat-264	126	38	ethnopharmacology	ethnopharmacology	NOUN
easat-264	126	39	,	,	PUNCT
easat-264	126	40	vol	vol	NOUN
easat-264	126	41	.	.	PROPN
easat-264	126	42	153	153	NUM
easat-264	126	43	,	,	PUNCT
easat-264	126	44	no	no	INTJ
easat-264	126	45	.	.	NOUN
easat-264	126	46	2	2	NUM
easat-264	126	47	,	,	PUNCT
easat-264	126	48	pp	pp	ADJ
easat-264	126	49	.	.	PUNCT
easat-264	127	1	535	535	NUM
easat-264	127	2	-	-	SYM
easat-264	127	3	539	539	NUM
easat-264	127	4	,	,	PUNCT
easat-264	127	5	2014	2014	NUM
easat-264	127	6	.	.	PUNCT
easat-264	128	1	https://doi.org/10.1016/j.jep.2014.02.048	https://doi.org/10.1016/j.jep.2014.02.048	PROPN
easat-264	129	1	https://doi.org/10.1007/s11017-019-09483-y	https://doi.org/10.1007/s11017-019-09483-y	PROPN
easat-264	129	2	https://doi.org/10.3389/fvets.2018.00014	https://doi.org/10.3389/fvets.2018.00014	PROPN
easat-264	129	3	https://doi.org/10.2174/1389201018666170224105600	https://doi.org/10.2174/1389201018666170224105600	DET
easat-264	129	4	https://doi.org/10.1016/j.autrev.2016.06.005	https://doi.org/10.1016/j.autrev.2016.06.005	NUM
easat-264	129	5	https://doi.org/10.1097/pp9.0000000000000002	https://doi.org/10.1097/pp9.0000000000000002	NOUN
easat-264	129	6	https://doi.org/10.1183/13993003.00391-2017	https://doi.org/10.1183/13993003.00391-2017	PART
easat-264	129	7	https://doi.org/10.1377/hlthaff.2017.1624	https://doi.org/10.1377/hlthaff.2017.1624	PROPN
easat-264	129	8	https://doi.org/10.6061/clinics/2017/e723	https://doi.org/10.6061/clinics/2017/e723	ADJ
easat-264	129	9	https://doi.org/10.1155/2010/130861	https://doi.org/10.1155/2010/130861	NOUN
easat-264	129	10	https://doi.org/10.1586/14737159.2015.975214	https://doi.org/10.1586/14737159.2015.975214	PUNCT
easat-264	130	1	https://doi.org/10.1515/cclm.2006.146	https://doi.org/10.1515/cclm.2006.146	PROPN
easat-264	130	2	https://doi.org/10.1016/s0248-8663(97)80931-9	https://doi.org/10.1016/s0248-8663(97)80931-9	VERB
easat-264	130	3	https://doi.org/10.1016/j.jaci.2014.10.015	https://doi.org/10.1016/j.jaci.2014.10.015	NOUN
easat-264	130	4	https://doi.org/10.1080/10408398.2012.702288	https://doi.org/10.1080/10408398.2012.702288	PROPN
easat-264	130	5	https://doi.org/10.1038/s41598-017-13011-0	https://doi.org/10.1038/s41598-017-13011-0	NUM
easat-264	130	6	https://doi.org/10.1016/j.jep.2014.02.048	https://doi.org/10.1016/j.jep.2014.02.048	NOUN