id	sid	tid	token	lemma	pos
easat-267	1	1	edelweiss	edelweiss	PROPN
easat-267	1	2	applied	apply	VERB
easat-267	1	3	science	science	NOUN
easat-267	1	4	and	and	CCONJ
easat-267	1	5	technology	technology	NOUN
easat-267	1	6	issn	issn	PROPN
easat-267	1	7	:	:	PUNCT
easat-267	1	8	2576	2576	NUM
easat-267	1	9	-	-	SYM
easat-267	1	10	8484	8484	NUM
easat-267	1	11	vol	vol	NOUN
easat-267	1	12	.	.	PROPN
easat-267	2	1	3	3	NUM
easat-267	2	2	,	,	PUNCT
easat-267	2	3	no	no	INTJ
easat-267	2	4	.	.	NOUN
easat-267	2	5	1	1	NUM
easat-267	2	6	,	,	PUNCT
easat-267	2	7	44	44	NUM
easat-267	2	8	-	-	SYM
easat-267	2	9	52	52	NUM
easat-267	2	10	2019	2019	NUM
easat-267	2	11	doi	doi	NOUN
easat-267	2	12	:	:	PUNCT
easat-267	2	13	10.33805/2576	10.33805/2576	NUM
easat-267	2	14	-	-	SYM
easat-267	2	15	8484.167	8484.167	NUM
easat-267	2	16	©	©	PROPN
easat-267	2	17	2019	2019	NUM
easat-267	2	18	by	by	ADP
easat-267	2	19	the	the	DET
easat-267	2	20	author	author	NOUN
easat-267	2	21	©	©	PROPN
easat-267	2	22	2019	2019	NUM
easat-267	2	23	by	by	ADP
easat-267	2	24	the	the	DET
easat-267	2	25	author	author	NOUN
easat-267	2	26	history	history	NOUN
easat-267	2	27	:	:	PUNCT
easat-267	2	28	received	receive	VERB
easat-267	2	29	:	:	PUNCT
easat-267	2	30	5	5	NUM
easat-267	2	31	october	october	NOUN
easat-267	2	32	2019	2019	NUM
easat-267	2	33	;	;	PUNCT
easat-267	2	34	accepted	accept	VERB
easat-267	2	35	:	:	PUNCT
easat-267	2	36	4	4	NUM
easat-267	2	37	november	november	PROPN
easat-267	2	38	2019	2019	NUM
easat-267	2	39	;	;	PUNCT
easat-267	2	40	published	publish	VERB
easat-267	2	41	:	:	PUNCT
easat-267	2	42	10	10	NUM
easat-267	2	43	november	november	PROPN
easat-267	2	44	2019	2019	NUM
easat-267	2	45	protective	protective	ADJ
easat-267	2	46	resistance	resistance	NOUN
easat-267	2	47	by	by	ADP
easat-267	2	48	human	human	ADJ
easat-267	2	49	g6pd	g6pd	NOUN
easat-267	2	50	enzyme	enzyme	NOUN
easat-267	2	51	deficiency	deficiency	NOUN
easat-267	2	52	and	and	CCONJ
easat-267	2	53	hemoglobin	hemoglobin	NOUN
easat-267	2	54	variants	variant	NOUN
easat-267	2	55	against	against	ADP
easat-267	2	56	malaria	malaria	NOUN
easat-267	2	57	and	and	CCONJ
easat-267	2	58	natural	natural	ADJ
easat-267	2	59	selection	selection	NOUN
easat-267	2	60	:	:	PUNCT
easat-267	2	61	further	further	ADJ
easat-267	2	62	evidence	evidence	NOUN
easat-267	2	63	from	from	ADP
easat-267	2	64	review	review	NOUN
easat-267	2	65	of	of	ADP
easat-267	2	66	new	new	ADJ
easat-267	2	67	studies	study	NOUN
easat-267	2	68	balgir	balgir	VERB
easat-267	2	69	rs	rs	PROPN
easat-267	2	70	department	department	PROPN
easat-267	2	71	of	of	ADP
easat-267	2	72	biochemistry	biochemistry	PROPN
easat-267	2	73	,	,	PUNCT
easat-267	2	74	national	national	PROPN
easat-267	2	75	institute	institute	NOUN
easat-267	2	76	for	for	ADP
easat-267	2	77	research	research	NOUN
easat-267	2	78	in	in	ADP
easat-267	2	79	tribal	tribal	ADJ
easat-267	2	80	health	health	PROPN
easat-267	2	81	(	(	PUNCT
easat-267	2	82	indian	indian	PROPN
easat-267	2	83	council	council	PROPN
easat-267	2	84	of	of	ADP
easat-267	2	85	medical	medical	ADJ
easat-267	2	86	research	research	PROPN
easat-267	2	87	)	)	PUNCT
easat-267	2	88	,	,	PUNCT
easat-267	2	89	jabalpur	jabalpur	PROPN
easat-267	2	90	,	,	PUNCT
easat-267	2	91	madhya	madhya	PROPN
easat-267	2	92	pradesh	pradesh	PROPN
easat-267	2	93	,	,	PUNCT
easat-267	2	94	india	india	PROPN
easat-267	2	95	;	;	PUNCT
easat-267	2	96	balgirrs@yahoo.co.in	balgirrs@yahoo.co.in	NOUN
easat-267	2	97	(	(	PUNCT
easat-267	2	98	b.r.s	b.r.s	NOUN
easat-267	2	99	.	.	PUNCT
easat-267	2	100	)	)	PUNCT
easat-267	2	101	.	.	PUNCT
easat-267	3	1	abstract	abstract	ADJ
easat-267	3	2	:	:	PUNCT
easat-267	3	3	main	main	ADJ
easat-267	3	4	objective	objective	NOUN
easat-267	3	5	of	of	ADP
easat-267	3	6	this	this	DET
easat-267	3	7	article	article	NOUN
easat-267	3	8	is	be	AUX
easat-267	3	9	to	to	PART
easat-267	3	10	review	review	VERB
easat-267	3	11	and	and	CCONJ
easat-267	3	12	evaluate	evaluate	VERB
easat-267	3	13	recent	recent	ADJ
easat-267	3	14	red	red	ADJ
easat-267	3	15	cell	cell	NOUN
easat-267	3	16	variant	variant	NOUN
easat-267	3	17	studies	study	NOUN
easat-267	3	18	for	for	ADP
easat-267	3	19	protection	protection	NOUN
easat-267	3	20	against	against	ADP
easat-267	3	21	malaria	malaria	NOUN
easat-267	3	22	and	and	CCONJ
easat-267	3	23	natural	natural	ADJ
easat-267	3	24	selection	selection	NOUN
easat-267	3	25	.	.	PUNCT
easat-267	4	1	malaria	malaria	NOUN
easat-267	4	2	is	be	AUX
easat-267	4	3	a	a	DET
easat-267	4	4	parasitic	parasitic	ADJ
easat-267	4	5	disease	disease	NOUN
easat-267	4	6	highly	highly	ADV
easat-267	4	7	widespread	widespread	ADJ
easat-267	4	8	in	in	ADP
easat-267	4	9	tropical	tropical	ADJ
easat-267	4	10	and	and	CCONJ
easat-267	4	11	subtropical	subtropical	ADJ
easat-267	4	12	regions	region	NOUN
easat-267	4	13	of	of	ADP
easat-267	4	14	the	the	DET
easat-267	4	15	world	world	NOUN
easat-267	4	16	.	.	PUNCT
easat-267	5	1	it	it	PRON
easat-267	5	2	is	be	AUX
easat-267	5	3	also	also	ADV
easat-267	5	4	one	one	NUM
easat-267	5	5	of	of	ADP
easat-267	5	6	the	the	DET
easat-267	5	7	leading	lead	VERB
easat-267	5	8	causes	cause	NOUN
easat-267	5	9	of	of	ADP
easat-267	5	10	death	death	NOUN
easat-267	5	11	worldwide	worldwide	ADV
easat-267	5	12	and	and	CCONJ
easat-267	5	13	genes	gene	NOUN
easat-267	5	14	involved	involve	VERB
easat-267	5	15	in	in	ADP
easat-267	5	16	malaria	malaria	NOUN
easat-267	5	17	resistance	resistance	NOUN
easat-267	5	18	are	be	AUX
easat-267	5	19	the	the	DET
easat-267	5	20	most	most	ADV
easat-267	5	21	important	important	ADJ
easat-267	5	22	for	for	ADP
easat-267	5	23	natural	natural	ADJ
easat-267	5	24	selection	selection	NOUN
easat-267	5	25	in	in	ADP
easat-267	5	26	human	human	ADJ
easat-267	5	27	populations	population	NOUN
easat-267	5	28	.	.	PUNCT
easat-267	6	1	multiple	multiple	ADJ
easat-267	6	2	red	red	ADJ
easat-267	6	3	cell	cell	NOUN
easat-267	6	4	variants	variant	NOUN
easat-267	6	5	,	,	PUNCT
easat-267	6	6	which	which	PRON
easat-267	6	7	evolved	evolve	VERB
easat-267	6	8	probably	probably	ADV
easat-267	6	9	to	to	PART
easat-267	6	10	counter	counter	VERB
easat-267	6	11	the	the	DET
easat-267	6	12	lethal	lethal	ADJ
easat-267	6	13	effects	effect	NOUN
easat-267	6	14	of	of	ADP
easat-267	6	15	malaria	malaria	NOUN
easat-267	6	16	and	and	CCONJ
easat-267	6	17	confer	confer	VERB
easat-267	6	18	protection	protection	NOUN
easat-267	6	19	against	against	ADP
easat-267	6	20	malaria	malaria	NOUN
easat-267	6	21	through	through	ADP
easat-267	6	22	different	different	ADJ
easat-267	6	23	mechanisms	mechanism	NOUN
easat-267	6	24	,	,	PUNCT
easat-267	6	25	show	show	VERB
easat-267	6	26	high	high	ADJ
easat-267	6	27	frequencies	frequency	NOUN
easat-267	6	28	in	in	ADP
easat-267	6	29	malaria	malaria	ADJ
easat-267	6	30	endemic	endemic	ADJ
easat-267	6	31	vulnerable	vulnerable	ADJ
easat-267	6	32	populations	population	NOUN
easat-267	6	33	.	.	PUNCT
easat-267	7	1	different	different	ADJ
easat-267	7	2	natural	natural	ADJ
easat-267	7	3	protective	protective	ADJ
easat-267	7	4	/	/	SYM
easat-267	7	5	resistance	resistance	NOUN
easat-267	7	6	mechanisms	mechanism	NOUN
easat-267	7	7	including	include	VERB
easat-267	7	8	hampering	hamper	VERB
easat-267	7	9	of	of	ADP
easat-267	7	10	parasite	parasite	NOUN
easat-267	7	11	growth	growth	NOUN
easat-267	7	12	,	,	PUNCT
easat-267	7	13	invasion	invasion	NOUN
easat-267	7	14	related	relate	VERB
easat-267	7	15	immunological	immunological	ADJ
easat-267	7	16	responses	response	NOUN
easat-267	7	17	or	or	CCONJ
easat-267	7	18	rapidly	rapidly	ADV
easat-267	7	19	elimination	elimination	NOUN
easat-267	7	20	of	of	ADP
easat-267	7	21	malaria	malaria	NOUN
easat-267	7	22	parasite	parasite	NOUN
easat-267	7	23	from	from	ADP
easat-267	7	24	the	the	DET
easat-267	7	25	infected	infected	ADJ
easat-267	7	26	erythrocytes	erythrocyte	NOUN
easat-267	7	27	of	of	ADP
easat-267	7	28	host	host	NOUN
easat-267	7	29	have	have	AUX
easat-267	7	30	briefly	briefly	ADV
easat-267	7	31	been	be	AUX
easat-267	7	32	discussed	discuss	VERB
easat-267	7	33	,	,	PUNCT
easat-267	7	34	evaluated	evaluate	VERB
easat-267	7	35	,	,	PUNCT
easat-267	7	36	and	and	CCONJ
easat-267	7	37	reviewed	review	VERB
easat-267	7	38	.	.	PUNCT
easat-267	8	1	conclusions	conclusion	NOUN
easat-267	8	2	drawn	draw	VERB
easat-267	8	3	have	have	AUX
easat-267	8	4	been	be	AUX
easat-267	8	5	projected	project	VERB
easat-267	8	6	here	here	ADV
easat-267	8	7	.	.	PUNCT
easat-267	9	1	high	high	ADJ
easat-267	9	2	frequency	frequency	NOUN
easat-267	9	3	of	of	ADP
easat-267	9	4	inherited	inherit	VERB
easat-267	9	5	hemoglobin	hemoglobin	NOUN
easat-267	9	6	disorders	disorder	NOUN
easat-267	9	7	including	include	VERB
easat-267	9	8	thalassemias	thalassemia	NOUN
easat-267	9	9	,	,	PUNCT
easat-267	9	10	and	and	CCONJ
easat-267	9	11	red	red	ADJ
easat-267	9	12	cell	cell	NOUN
easat-267	9	13	g6pd	g6pd	NOUN
easat-267	9	14	enzyme	enzyme	NOUN
easat-267	9	15	deficiency	deficiency	NOUN
easat-267	9	16	,	,	PUNCT
easat-267	9	17	which	which	PRON
easat-267	9	18	seemed	seem	VERB
easat-267	9	19	to	to	PART
easat-267	9	20	evolve	evolve	VERB
easat-267	9	21	simultaneously	simultaneously	ADV
easat-267	9	22	in	in	ADP
easat-267	9	23	relation	relation	NOUN
easat-267	9	24	to	to	ADP
easat-267	9	25	malaria	malaria	NOUN
easat-267	9	26	,	,	PUNCT
easat-267	9	27	and	and	CCONJ
easat-267	9	28	high	high	ADJ
easat-267	9	29	mortality	mortality	NOUN
easat-267	9	30	caused	cause	VERB
easat-267	9	31	by	by	ADP
easat-267	9	32	plasmodium	plasmodium	NOUN
easat-267	9	33	falciparum	falciparum	ADJ
easat-267	9	34	malaria	malaria	NOUN
easat-267	9	35	in	in	ADP
easat-267	9	36	different	different	ADJ
easat-267	9	37	vulnerable	vulnerable	ADJ
easat-267	9	38	populations	population	NOUN
easat-267	9	39	of	of	ADP
easat-267	9	40	tropical	tropical	ADJ
easat-267	9	41	and	and	CCONJ
easat-267	9	42	subtropical	subtropical	ADJ
easat-267	9	43	parts	part	NOUN
easat-267	9	44	of	of	ADP
easat-267	9	45	world	world	NOUN
easat-267	9	46	,	,	PUNCT
easat-267	9	47	confirm	confirm	VERB
easat-267	9	48	that	that	SCONJ
easat-267	9	49	the	the	DET
easat-267	9	50	natural	natural	ADJ
easat-267	9	51	selection	selection	NOUN
easat-267	9	52	is	be	AUX
easat-267	9	53	certainly	certainly	ADV
easat-267	9	54	operating	operate	VERB
easat-267	9	55	against	against	ADP
easat-267	9	56	malaria	malaria	NOUN
easat-267	9	57	in	in	ADP
easat-267	9	58	one	one	NUM
easat-267	9	59	way	way	NOUN
easat-267	9	60	or	or	CCONJ
easat-267	9	61	another	another	PRON
easat-267	9	62	;	;	PUNCT
easat-267	9	63	and	and	CCONJ
easat-267	9	64	human	human	ADJ
easat-267	9	65	population	population	NOUN
easat-267	9	66	genetics	genetic	NOUN
easat-267	9	67	have	have	AUX
easat-267	9	68	distinctly	distinctly	ADV
easat-267	9	69	played	play	VERB
easat-267	9	70	a	a	DET
easat-267	9	71	significant	significant	ADJ
easat-267	9	72	role	role	NOUN
easat-267	9	73	in	in	ADP
easat-267	9	74	the	the	DET
easat-267	9	75	co	co	NOUN
easat-267	9	76	-	-	NOUN
easat-267	9	77	evolution	evolution	NOUN
easat-267	9	78	of	of	ADP
easat-267	9	79	host	host	NOUN
easat-267	9	80	and	and	CCONJ
easat-267	9	81	malaria	malaria	NOUN
easat-267	9	82	.	.	PUNCT
easat-267	10	1	the	the	DET
easat-267	10	2	inverse	inverse	NOUN
easat-267	10	3	relationship	relationship	NOUN
easat-267	10	4	between	between	ADP
easat-267	10	5	sickle	sickle	NOUN
easat-267	10	6	cell	cell	NOUN
easat-267	10	7	trait	trait	NOUN
easat-267	10	8	and	and	CCONJ
easat-267	10	9	g6pd	g6pd	NOUN
easat-267	10	10	deficiency	deficiency	NOUN
easat-267	10	11	and	and	CCONJ
easat-267	10	12	vice	vice	NOUN
easat-267	10	13	versa	versa	ADV
easat-267	10	14	,	,	PUNCT
easat-267	10	15	revealed	reveal	VERB
easat-267	10	16	by	by	ADP
easat-267	10	17	allele	allele	NOUN
easat-267	10	18	frequencies	frequency	NOUN
easat-267	10	19	distribution	distribution	NOUN
easat-267	10	20	shown	show	VERB
easat-267	10	21	in	in	ADP
easat-267	10	22	our	our	PRON
easat-267	10	23	previous	previous	ADJ
easat-267	10	24	studies	study	NOUN
easat-267	10	25	,	,	PUNCT
easat-267	10	26	is	be	AUX
easat-267	10	27	a	a	DET
easat-267	10	28	testimony	testimony	NOUN
easat-267	10	29	of	of	ADP
easat-267	10	30	disequilibrium	disequilibrium	NOUN
easat-267	10	31	,	,	PUNCT
easat-267	10	32	as	as	SCONJ
easat-267	10	33	sickle	sickle	NOUN
easat-267	10	34	cell	cell	NOUN
easat-267	10	35	allele	allele	NOUN
easat-267	10	36	being	be	AUX
easat-267	10	37	replaced	replace	VERB
easat-267	10	38	by	by	ADP
easat-267	10	39	g6pd	g6pd	NOUN
easat-267	10	40	deficiency	deficiency	NOUN
easat-267	10	41	allele	allele	NOUN
easat-267	10	42	in	in	ADP
easat-267	10	43	populations	population	NOUN
easat-267	10	44	of	of	ADP
easat-267	10	45	central	central	ADJ
easat-267	10	46	india	india	PROPN
easat-267	10	47	.	.	PUNCT
easat-267	11	1	positive	positive	ADJ
easat-267	11	2	natural	natural	ADJ
easat-267	11	3	selection	selection	NOUN
easat-267	11	4	plays	play	VERB
easat-267	11	5	a	a	DET
easat-267	11	6	definite	definite	ADJ
easat-267	11	7	role	role	NOUN
easat-267	11	8	against	against	ADP
easat-267	11	9	malaria	malaria	NOUN
easat-267	11	10	for	for	ADP
easat-267	11	11	maintaining	maintain	VERB
easat-267	11	12	balance	balance	NOUN
easat-267	11	13	in	in	ADP
easat-267	11	14	high	high	ADJ
easat-267	11	15	frequency	frequency	NOUN
easat-267	11	16	endemic	endemic	ADJ
easat-267	11	17	populations	population	NOUN
easat-267	11	18	.	.	PUNCT
easat-267	12	1	keywords	keyword	NOUN
easat-267	12	2	:	:	PUNCT
easat-267	12	3	g6pd	g6pd	NOUN
easat-267	12	4	deficiency	deficiency	NOUN
easat-267	12	5	,	,	PUNCT
easat-267	12	6	hemoglobin	hemoglobin	NOUN
easat-267	12	7	variants	variant	NOUN
easat-267	12	8	,	,	PUNCT
easat-267	12	9	thalassemia	thalassemia	NOUN
easat-267	12	10	,	,	PUNCT
easat-267	12	11	protective	protective	ADJ
easat-267	12	12	resistance	resistance	NOUN
easat-267	12	13	,	,	PUNCT
easat-267	12	14	inverse	inverse	NOUN
easat-267	12	15	relationship	relationship	NOUN
easat-267	12	16	,	,	PUNCT
easat-267	12	17	malaria	malaria	NOUN
easat-267	12	18	,	,	PUNCT
easat-267	12	19	natural	natural	ADJ
easat-267	12	20	selection	selection	NOUN
easat-267	12	21	.	.	PUNCT
easat-267	13	1	1	1	X
easat-267	13	2	.	.	X
easat-267	13	3	introduction	introduction	NOUN
easat-267	13	4	there	there	PRON
easat-267	13	5	is	be	VERB
easat-267	13	6	a	a	DET
easat-267	13	7	need	need	NOUN
easat-267	13	8	to	to	PART
easat-267	13	9	recognize	recognize	VERB
easat-267	13	10	and	and	CCONJ
easat-267	13	11	respect	respect	VERB
easat-267	13	12	the	the	DET
easat-267	13	13	fact	fact	NOUN
easat-267	13	14	that	that	SCONJ
easat-267	13	15	each	each	DET
easat-267	13	16	person	person	NOUN
easat-267	13	17	is	be	AUX
easat-267	13	18	a	a	DET
easat-267	13	19	unique	unique	ADJ
easat-267	13	20	in	in	ADP
easat-267	13	21	this	this	DET
easat-267	13	22	world	world	NOUN
easat-267	13	23	with	with	ADP
easat-267	13	24	its	its	PRON
easat-267	13	25	gifted	gifted	ADJ
easat-267	13	26	qualities	quality	NOUN
easat-267	13	27	and	and	CCONJ
easat-267	13	28	genetic	genetic	ADJ
easat-267	13	29	endowments	endowment	NOUN
easat-267	13	30	.	.	PUNCT
easat-267	14	1	every	every	DET
easat-267	14	2	human	human	NOUN
easat-267	14	3	-	-	PUNCT
easat-267	14	4	being	being	NOUN
easat-267	14	5	fortunately	fortunately	ADV
easat-267	14	6	or	or	CCONJ
easat-267	14	7	unfortunately	unfortunately	ADV
easat-267	14	8	needs	need	VERB
easat-267	14	9	to	to	PART
easat-267	14	10	be	be	AUX
easat-267	14	11	aware	aware	ADJ
easat-267	14	12	of	of	ADP
easat-267	14	13	the	the	DET
easat-267	14	14	fact	fact	NOUN
easat-267	14	15	that	that	SCONJ
easat-267	14	16	the	the	DET
easat-267	14	17	present	present	ADJ
easat-267	14	18	human	human	ADJ
easat-267	14	19	body	body	NOUN
easat-267	14	20	shape	shape	NOUN
easat-267	14	21	,	,	PUNCT
easat-267	14	22	size	size	NOUN
easat-267	14	23	and	and	CCONJ
easat-267	14	24	figure	figure	NOUN
easat-267	14	25	is	be	AUX
easat-267	14	26	going	go	VERB
easat-267	14	27	to	to	PART
easat-267	14	28	give	give	VERB
easat-267	14	29	up	up	ADP
easat-267	14	30	one	one	NUM
easat-267	14	31	day	day	NOUN
easat-267	14	32	or	or	CCONJ
easat-267	14	33	another	another	DET
easat-267	14	34	day	day	NOUN
easat-267	14	35	and	and	CCONJ
easat-267	14	36	what	what	PRON
easat-267	14	37	will	will	AUX
easat-267	14	38	stay	stay	VERB
easat-267	14	39	in	in	ADP
easat-267	14	40	the	the	DET
easat-267	14	41	world	world	NOUN
easat-267	14	42	,	,	PUNCT
easat-267	14	43	are	be	AUX
easat-267	14	44	the	the	DET
easat-267	14	45	novel	novel	ADJ
easat-267	14	46	deeds	deed	NOUN
easat-267	14	47	,	,	PUNCT
easat-267	14	48	enlightening	enlightening	ADJ
easat-267	14	49	thoughts	thought	NOUN
easat-267	14	50	,	,	PUNCT
easat-267	14	51	genuine	genuine	ADJ
easat-267	14	52	and	and	CCONJ
easat-267	14	53	truthful	truthful	ADJ
easat-267	14	54	contributions	contribution	NOUN
easat-267	14	55	and	and	CCONJ
easat-267	14	56	distinguished	distinguished	ADJ
easat-267	14	57	achievements	achievement	NOUN
easat-267	14	58	during	during	ADP
easat-267	14	59	the	the	DET
easat-267	14	60	life	life	NOUN
easat-267	14	61	span	span	NOUN
easat-267	14	62	.	.	PUNCT
easat-267	15	1	human	human	ADJ
easat-267	15	2	health	health	NOUN
easat-267	15	3	and	and	CCONJ
easat-267	15	4	disease	disease	NOUN
easat-267	15	5	are	be	AUX
easat-267	15	6	the	the	DET
easat-267	15	7	relative	relative	ADJ
easat-267	15	8	terms	term	NOUN
easat-267	15	9	which	which	PRON
easat-267	15	10	depend	depend	VERB
easat-267	15	11	on	on	ADP
easat-267	15	12	the	the	DET
easat-267	15	13	healthy	healthy	ADJ
easat-267	15	14	and	and	CCONJ
easat-267	15	15	balanced	balance	VERB
easat-267	15	16	up	up	ADP
easat-267	15	17	keep	keep	NOUN
easat-267	15	18	against	against	ADP
easat-267	15	19	the	the	DET
easat-267	15	20	odd	odd	ADJ
easat-267	15	21	surrounding	surround	VERB
easat-267	15	22	conditions	condition	NOUN
easat-267	15	23	.	.	PUNCT
easat-267	16	1	when	when	SCONJ
easat-267	16	2	the	the	DET
easat-267	16	3	human	human	ADJ
easat-267	16	4	populations	population	NOUN
easat-267	16	5	are	be	AUX
easat-267	16	6	subject	subject	ADJ
easat-267	16	7	to	to	ADP
easat-267	16	8	dwelling	dwell	VERB
easat-267	16	9	in	in	ADP
easat-267	16	10	varied	varied	ADJ
easat-267	16	11	geography	geography	NOUN
easat-267	16	12	,	,	PUNCT
easat-267	16	13	ecology	ecology	NOUN
easat-267	16	14	,	,	PUNCT
easat-267	16	15	different	different	ADJ
easat-267	16	16	environmental	environmental	ADJ
easat-267	16	17	conditions	condition	NOUN
easat-267	16	18	,	,	PUNCT
easat-267	16	19	climatic	climatic	ADJ
easat-267	16	20	fluctuations	fluctuation	NOUN
easat-267	16	21	and	and	CCONJ
easat-267	16	22	changes	change	NOUN
easat-267	16	23	,	,	PUNCT
easat-267	16	24	disease	disease	NOUN
easat-267	16	25	susceptibility	susceptibility	NOUN
easat-267	16	26	,	,	PUNCT
easat-267	16	27	persistence	persistence	NOUN
easat-267	16	28	of	of	ADP
easat-267	16	29	diseases	disease	NOUN
easat-267	16	30	,	,	PUNCT
easat-267	16	31	or	or	CCONJ
easat-267	16	32	bio	bio	ADJ
easat-267	16	33	-	-	ADJ
easat-267	16	34	social	social	ADJ
easat-267	16	35	inherent	inherent	ADJ
easat-267	16	36	pressures	pressure	NOUN
easat-267	16	37	,	,	PUNCT
easat-267	16	38	the	the	DET
easat-267	16	39	natural	natural	ADJ
easat-267	16	40	selection	selection	NOUN
easat-267	16	41	may	may	AUX
easat-267	16	42	alter	alter	VERB
easat-267	16	43	the	the	DET
easat-267	16	44	genetic	genetic	ADJ
easat-267	16	45	allele	allele	NOUN
easat-267	16	46	frequencies	frequency	NOUN
easat-267	16	47	in	in	ADP
easat-267	16	48	one	one	NUM
easat-267	16	49	population	population	NOUN
easat-267	16	50	relative	relative	ADJ
easat-267	16	51	to	to	ADP
easat-267	16	52	another	another	PRON
easat-267	16	53	[	[	X
easat-267	16	54	1,2	1,2	NUM
easat-267	16	55	]	]	PUNCT
easat-267	16	56	.	.	PUNCT
easat-267	17	1	positive	positive	ADJ
easat-267	17	2	natural	natural	ADJ
easat-267	17	3	selection	selection	NOUN
easat-267	17	4	the	the	DET
easat-267	17	5	phenomenon	phenomenon	NOUN
easat-267	17	6	that	that	PRON
easat-267	17	7	accounts	account	VERB
easat-267	17	8	for	for	ADP
easat-267	17	9	the	the	DET
easat-267	17	10	increase	increase	NOUN
easat-267	17	11	in	in	ADP
easat-267	17	12	the	the	DET
easat-267	17	13	prevalence	prevalence	NOUN
easat-267	17	14	of	of	ADP
easat-267	17	15	advantageous	advantageous	ADJ
easat-267	17	16	traits	trait	NOUN
easat-267	17	17	in	in	ADP
easat-267	17	18	a	a	DET
easat-267	17	19	population	population	NOUN
easat-267	17	20	has	have	AUX
easat-267	17	21	played	play	VERB
easat-267	17	22	an	an	DET
easat-267	17	23	important	important	ADJ
easat-267	17	24	role	role	NOUN
easat-267	17	25	in	in	ADP
easat-267	17	26	human	human	ADJ
easat-267	17	27	development	development	NOUN
easat-267	17	28	and	and	CCONJ
easat-267	17	29	evolution	evolution	NOUN
easat-267	17	30	as	as	ADP
easat-267	17	31	a	a	DET
easat-267	17	32	species	specie	NOUN
easat-267	17	33	.	.	PUNCT
easat-267	18	1	large	large	ADJ
easat-267	18	2	differences	difference	NOUN
easat-267	18	3	in	in	ADP
easat-267	18	4	allele	allele	NOUN
easat-267	18	5	frequencies	frequency	NOUN
easat-267	18	6	between	between	ADP
easat-267	18	7	populations	population	NOUN
easat-267	18	8	,	,	PUNCT
easat-267	18	9	thus	thus	ADV
easat-267	18	10	,	,	PUNCT
easat-267	18	11	are	be	AUX
easat-267	18	12	the	the	DET
easat-267	18	13	signals	signal	NOUN
easat-267	18	14	in	in	ADP
easat-267	18	15	the	the	DET
easat-267	18	16	genome	genome	NOUN
easat-267	18	17	that	that	PRON
easat-267	18	18	have	have	AUX
easat-267	18	19	undergone	undergo	VERB
easat-267	18	20	selection	selection	NOUN
easat-267	18	21	.	.	PUNCT
easat-267	19	1	other	other	ADJ
easat-267	19	2	signals	signal	NOUN
easat-267	19	3	of	of	ADP
easat-267	19	4	recent	recent	ADJ
easat-267	19	5	positive	positive	ADJ
easat-267	19	6	selection	selection	NOUN
easat-267	19	7	include	include	VERB
easat-267	19	8	the	the	DET
easat-267	19	9	long	long	ADJ
easat-267	19	10	haplotypes	haplotype	NOUN
easat-267	19	11	,	,	PUNCT
easat-267	19	12	and	and	CCONJ
easat-267	19	13	reduced	reduce	VERB
easat-267	19	14	allelic	allelic	ADJ
easat-267	19	15	variation	variation	NOUN
easat-267	19	16	in	in	ADP
easat-267	19	17	the	the	DET
easat-267	19	18	regions	region	NOUN
easat-267	19	19	around	around	ADP
easat-267	19	20	the	the	DET
easat-267	19	21	selected	select	VERB
easat-267	19	22	variants	variant	NOUN
easat-267	19	23	.	.	PUNCT
easat-267	20	1	therefore	therefore	ADV
easat-267	20	2	,	,	PUNCT
easat-267	20	3	the	the	DET
easat-267	20	4	characterization	characterization	NOUN
easat-267	20	5	of	of	ADP
easat-267	20	6	signatures	signature	NOUN
easat-267	20	7	of	of	ADP
easat-267	20	8	positive	positive	ADJ
easat-267	20	9	selection	selection	NOUN
easat-267	20	10	in	in	ADP
easat-267	20	11	genes	gene	NOUN
easat-267	20	12	,	,	PUNCT
easat-267	20	13	that	that	PRON
easat-267	20	14	are	be	AUX
easat-267	20	15	of	of	ADP
easat-267	20	16	adaptive	adaptive	ADJ
easat-267	20	17	significance	significance	NOUN
easat-267	20	18	in	in	ADP
easat-267	20	19	human	human	ADJ
easat-267	20	20	populations	population	NOUN
easat-267	20	21	,	,	PUNCT
easat-267	20	22	have	have	VERB
easat-267	20	23	greater	great	ADJ
easat-267	20	24	medical	medical	ADJ
easat-267	20	25	relevance	relevance	NOUN
easat-267	20	26	for	for	ADP
easat-267	20	27	identifying	identify	VERB
easat-267	20	28	the	the	DET
easat-267	20	29	functionally	functionally	ADV
easat-267	20	30	significant	significant	ADJ
easat-267	20	31	variants	variant	NOUN
easat-267	20	32	that	that	PRON
easat-267	20	33	play	play	VERB
easat-267	20	34	important	important	ADJ
easat-267	20	35	roles	role	NOUN
easat-267	20	36	in	in	ADP
easat-267	20	37	health	health	NOUN
easat-267	20	38	and	and	CCONJ
easat-267	20	39	disease	disease	NOUN
easat-267	20	40	scenario	scenario	NOUN
easat-267	20	41	of	of	ADP
easat-267	20	42	the	the	DET
easat-267	20	43	host	host	NOUN
easat-267	20	44	[	[	X
easat-267	20	45	1,2	1,2	NUM
easat-267	20	46	]	]	PUNCT
easat-267	20	47	.	.	PUNCT
easat-267	21	1	moreover	moreover	ADV
easat-267	21	2	,	,	PUNCT
easat-267	21	3	different	different	ADJ
easat-267	21	4	persons	person	NOUN
easat-267	21	5	may	may	AUX
easat-267	21	6	differ	differ	VERB
easat-267	21	7	in	in	ADP
easat-267	21	8	genetic	genetic	ADJ
easat-267	21	9	constitution	constitution	NOUN
easat-267	21	10	and	and	CCONJ
easat-267	21	11	its	its	PRON
easat-267	21	12	response	response	NOUN
easat-267	21	13	to	to	ADP
easat-267	21	14	an	an	DET
easat-267	21	15	infectious	infectious	ADJ
easat-267	21	16	disease	disease	NOUN
easat-267	21	17	for	for	ADP
easat-267	21	18	example	example	NOUN
easat-267	21	19	,	,	PUNCT
easat-267	21	20	the	the	DET
easat-267	21	21	malaria	malaria	NOUN
easat-267	21	22	.	.	PUNCT
easat-267	22	1	malaria	malaria	NOUN
easat-267	22	2	has	have	AUX
easat-267	22	3	been	be	AUX
easat-267	22	4	one	one	NUM
easat-267	22	5	of	of	ADP
easat-267	22	6	the	the	DET
easat-267	22	7	most	most	ADV
easat-267	22	8	prevalent	prevalent	ADJ
easat-267	22	9	and	and	CCONJ
easat-267	22	10	successful	successful	ADJ
easat-267	22	11	parasitic	parasitic	ADJ
easat-267	22	12	diseases	disease	NOUN
easat-267	22	13	widely	widely	ADV
easat-267	22	14	spread	spread	VERB
easat-267	22	15	throughout	throughout	ADP
easat-267	22	16	the	the	DET
easat-267	22	17	globe	globe	NOUN
easat-267	22	18	.	.	PUNCT
easat-267	23	1	plasmodium	plasmodium	NOUN
easat-267	23	2	parasites	parasite	NOUN
easat-267	23	3	,	,	PUNCT
easat-267	23	4	due	due	ADP
easat-267	23	5	to	to	ADP
easat-267	23	6	multiple	multiple	ADJ
easat-267	23	7	factors	factor	NOUN
easat-267	23	8	,	,	PUNCT
easat-267	23	9	have	have	VERB
easat-267	23	10	complex	complex	ADJ
easat-267	23	11	biology	biology	NOUN
easat-267	23	12	,	,	PUNCT
easat-267	23	13	high	high	ADJ
easat-267	23	14	polymorphism	polymorphism	NOUN
easat-267	23	15	,	,	PUNCT
easat-267	23	16	increasingly	increasingly	ADV
easat-267	23	17	high	high	ADJ
easat-267	23	18	resistance	resistance	NOUN
easat-267	23	19	to	to	ADP
easat-267	23	20	antimalarial	antimalarial	ADJ
easat-267	23	21	drugs	drug	NOUN
easat-267	23	22	in	in	ADP
easat-267	23	23	many	many	ADJ
easat-267	23	24	endemic	endemic	ADJ
easat-267	23	25	regions	region	NOUN
easat-267	23	26	of	of	ADP
easat-267	23	27	the	the	DET
easat-267	23	28	world	world	NOUN
easat-267	23	29	.	.	PUNCT
easat-267	24	1	as	as	ADP
easat-267	24	2	a	a	DET
easat-267	24	3	result	result	NOUN
easat-267	24	4	of	of	ADP
easat-267	24	5	interaction	interaction	NOUN
easat-267	24	6	between	between	ADP
easat-267	24	7	malaria	malaria	NOUN
easat-267	24	8	parasites	parasite	NOUN
easat-267	24	9	and	and	CCONJ
easat-267	24	10	human	human	ADJ
easat-267	24	11	species	specie	NOUN
easat-267	24	12	have	have	AUX
easat-267	24	13	led	lead	VERB
easat-267	24	14	to	to	ADP
easat-267	24	15	fixation	fixation	NOUN
easat-267	24	16	of	of	ADP
easat-267	24	17	several	several	ADJ
easat-267	24	18	inherited	inherit	VERB
easat-267	24	19	alterations	alteration	NOUN
easat-267	24	20	in	in	ADP
easat-267	24	21	many	many	ADJ
easat-267	24	22	populations	population	NOUN
easat-267	24	23	so	so	SCONJ
easat-267	24	24	that	that	SCONJ
easat-267	24	25	some	some	PRON
easat-267	24	26	of	of	ADP
easat-267	24	27	the	the	DET
easat-267	24	28	underlying	underlie	VERB
easat-267	24	29	mechanisms	mechanism	NOUN
easat-267	24	30	confer	confer	VERB
easat-267	24	31	protection	protection	NOUN
easat-267	24	32	against	against	ADP
easat-267	24	33	malaria	malaria	NOUN
easat-267	25	1	[	[	X
easat-267	25	2	1,2	1,2	NUM
easat-267	25	3	]	]	PUNCT
easat-267	25	4	.	.	PUNCT
easat-267	26	1	natural	natural	ADJ
easat-267	26	2	selection	selection	NOUN
easat-267	26	3	supports	support	VERB
easat-267	26	4	such	such	ADJ
easat-267	26	5	positively	positively	ADV
easat-267	26	6	involved	involve	VERB
easat-267	26	7	struggle	struggle	NOUN
easat-267	26	8	for	for	ADP
easat-267	26	9	existence	existence	NOUN
easat-267	26	10	of	of	ADP
easat-267	26	11	the	the	DET
easat-267	26	12	fittest	fit	ADJ
easat-267	26	13	of	of	ADP
easat-267	26	14	all	all	PRON
easat-267	26	15	.	.	PUNCT
easat-267	27	1	1.1	1.1	NUM
easat-267	27	2	.	.	PUNCT
easat-267	28	1	cardinal	cardinal	ADJ
easat-267	28	2	malaria	malaria	NOUN
easat-267	28	3	situation	situation	NOUN
easat-267	28	4	malaria	malaria	NOUN
easat-267	28	5	is	be	AUX
easat-267	28	6	a	a	DET
easat-267	28	7	parasitic	parasitic	ADJ
easat-267	28	8	disease	disease	NOUN
easat-267	28	9	highly	highly	ADV
easat-267	28	10	widespread	widespread	ADJ
easat-267	28	11	in	in	ADP
easat-267	28	12	tropical	tropical	ADJ
easat-267	28	13	and	and	CCONJ
easat-267	28	14	subtropical	subtropical	ADJ
easat-267	28	15	regions	region	NOUN
easat-267	28	16	of	of	ADP
easat-267	28	17	the	the	DET
easat-267	28	18	world	world	NOUN
easat-267	28	19	.	.	PUNCT
easat-267	29	1	this	this	DET
easat-267	29	2	disease	disease	NOUN
easat-267	29	3	is	be	AUX
easat-267	29	4	most	most	ADV
easat-267	29	5	commonly	commonly	ADV
easat-267	29	6	found	find	VERB
easat-267	29	7	in	in	ADP
easat-267	29	8	poor	poor	ADJ
easat-267	29	9	countries	country	NOUN
easat-267	29	10	,	,	PUNCT
easat-267	29	11	having	have	VERB
easat-267	29	12	less	less	ADV
easat-267	29	13	developed	develop	VERB
easat-267	29	14	systems	system	NOUN
easat-267	29	15	for	for	ADP
easat-267	29	16	health	health	NOUN
easat-267	29	17	infrastructure	infrastructure	NOUN
easat-267	29	18	,	,	PUNCT
easat-267	29	19	and	and	CCONJ
easat-267	29	20	inadequate	inadequate	ADJ
easat-267	29	21	control	control	NOUN
easat-267	29	22	and	and	CCONJ
easat-267	29	23	comprehensive	comprehensive	ADJ
easat-267	29	24	preventive	preventive	ADJ
easat-267	29	25	strategies	strategy	NOUN
easat-267	29	26	.	.	PUNCT
easat-267	30	1	high	high	ADJ
easat-267	30	2	rates	rate	NOUN
easat-267	30	3	of	of	ADP
easat-267	30	4	morbidity	morbidity	NOUN
easat-267	30	5	and	and	CCONJ
easat-267	30	6	mortality	mortality	NOUN
easat-267	30	7	can	can	AUX
easat-267	30	8	be	be	AUX
easat-267	30	9	attributed	attribute	VERB
easat-267	30	10	to	to	ADP
easat-267	30	11	the	the	DET
easat-267	30	12	lack	lack	NOUN
easat-267	30	13	of	of	ADP
easat-267	30	14	timely	timely	ADJ
easat-267	30	15	available	available	ADJ
easat-267	30	16	diagnostic	diagnostic	ADJ
easat-267	30	17	facilities	facility	NOUN
easat-267	30	18	,	,	PUNCT
easat-267	30	19	due	due	ADP
easat-267	30	20	to	to	ADP
easat-267	30	21	financial	financial	ADJ
easat-267	30	22	constraints	constraint	NOUN
easat-267	30	23	,	,	PUNCT
easat-267	30	24	and	and	CCONJ
easat-267	30	25	geographical	geographical	ADJ
easat-267	30	26	and	and	CCONJ
easat-267	30	27	transport	transport	NOUN
easat-267	30	28	barriers	barrier	NOUN
easat-267	30	29	,	,	PUNCT
easat-267	30	30	access	access	NOUN
easat-267	30	31	to	to	ADP
easat-267	30	32	effective	effective	ADJ
easat-267	30	33	treatment	treatment	NOUN
easat-267	30	34	due	due	ADP
easat-267	30	35	to	to	ADP
easat-267	30	36	insufficient	insufficient	ADJ
easat-267	30	37	supply	supply	NOUN
easat-267	30	38	of	of	ADP
easat-267	30	39	quality	quality	NOUN
easat-267	30	40	medicine	medicine	NOUN
easat-267	30	41	,	,	PUNCT
easat-267	30	42	and	and	CCONJ
easat-267	30	43	the	the	DET
easat-267	30	44	growing	grow	VERB
easat-267	30	45	parasite	parasite	ADJ
easat-267	30	46	resistance	resistance	NOUN
easat-267	30	47	to	to	ADP
easat-267	30	48	anti	anti	ADJ
easat-267	30	49	-	-	ADJ
easat-267	30	50	malarial	malarial	ADJ
easat-267	30	51	drugs	drug	NOUN
easat-267	30	52	such	such	ADJ
easat-267	30	53	as	as	ADP
easat-267	30	54	chloroquine	chloroquine	NOUN
easat-267	30	55	,	,	PUNCT
easat-267	30	56	pyrimethamine	pyrimethamine	NOUN
easat-267	30	57	,	,	PUNCT
easat-267	30	58	etc	etc	X
easat-267	30	59	.	.	X
easat-267	31	1	the	the	DET
easat-267	31	2	immune	immune	ADJ
easat-267	31	3	response	response	NOUN
easat-267	31	4	induced	induce	VERB
easat-267	31	5	in	in	ADP
easat-267	31	6	humans	human	NOUN
easat-267	31	7	by	by	ADP
easat-267	31	8	parasitic	parasitic	ADJ
easat-267	31	9	infection	infection	NOUN
easat-267	31	10	of	of	ADP
easat-267	31	11	malaria	malaria	NOUN
easat-267	31	12	is	be	AUX
easat-267	31	13	a	a	DET
easat-267	31	14	complex	complex	ADJ
easat-267	31	15	one	one	NOUN
easat-267	31	16	and	and	CCONJ
easat-267	31	17	it	it	PRON
easat-267	31	18	varies	vary	VERB
easat-267	31	19	depending	depend	VERB
easat-267	31	20	on	on	ADP
easat-267	31	21	genetic	genetic	ADJ
easat-267	31	22	make	make	NOUN
easat-267	31	23	-	-	PUNCT
easat-267	31	24	up	up	NOUN
easat-267	31	25	of	of	ADP
easat-267	31	26	the	the	DET
easat-267	31	27	host	host	NOUN
easat-267	31	28	,	,	PUNCT
easat-267	31	29	age	age	NOUN
easat-267	31	30	,	,	PUNCT
easat-267	31	31	epidemiological	epidemiological	ADJ
easat-267	31	32	factors	factor	NOUN
easat-267	31	33	,	,	PUNCT
easat-267	31	34	level	level	NOUN
easat-267	31	35	of	of	ADP
easat-267	31	36	malaria	malaria	NOUN
easat-267	31	37	endemicity	endemicity	NOUN
easat-267	31	38	,	,	PUNCT
easat-267	31	39	parasite	parasite	NOUN
easat-267	31	40	stage	stage	NOUN
easat-267	31	41	,	,	PUNCT
easat-267	31	42	parasite	parasite	NOUN
easat-267	31	43	species	specie	NOUN
easat-267	31	44	,	,	PUNCT
easat-267	31	45	availability	availability	NOUN
easat-267	31	46	of	of	ADP
easat-267	31	47	diagnostic	diagnostic	ADJ
easat-267	31	48	facilities	facility	NOUN
easat-267	31	49	and	and	CCONJ
easat-267	31	50	quality	quality	NOUN
easat-267	31	51	of	of	ADP
easat-267	31	52	treatment	treatment	NOUN
easat-267	31	53	,	,	PUNCT
easat-267	31	54	and	and	CCONJ
easat-267	31	55	repeated	repeat	VERB
easat-267	31	56	parasitic	parasitic	ADJ
easat-267	31	57	infection	infection	NOUN
easat-267	31	58	.	.	PUNCT
easat-267	32	1	both	both	PRON
easat-267	32	2	innate	innate	ADJ
easat-267	32	3	and	and	CCONJ
easat-267	32	4	acquired	acquire	VERB
easat-267	32	5	immunity	immunity	NOUN
easat-267	32	6	processes	process	NOUN
easat-267	32	7	are	be	AUX
easat-267	32	8	invoked	invoke	VERB
easat-267	32	9	vigorously	vigorously	ADV
easat-267	32	10	during	during	ADP
easat-267	32	11	the	the	DET
easat-267	32	12	infection	infection	NOUN
easat-267	32	13	.	.	PUNCT
easat-267	33	1	the	the	DET
easat-267	33	2	world	world	PROPN
easat-267	33	3	malaria	malaria	PROPN
easat-267	33	4	report	report	PROPN
easat-267	33	5	2017	2017	NUM
easat-267	33	6	presents	present	VERB
easat-267	33	7	a	a	DET
easat-267	33	8	comprehensive	comprehensive	ADJ
easat-267	33	9	state	state	NOUN
easat-267	33	10	of	of	ADP
easat-267	33	11	play	play	NOUN
easat-267	33	12	in	in	ADP
easat-267	33	13	global	global	ADJ
easat-267	33	14	progress	progress	NOUN
easat-267	33	15	in	in	ADP
easat-267	33	16	the	the	DET
easat-267	33	17	fight	fight	NOUN
easat-267	33	18	against	against	ADP
easat-267	33	19	malaria	malaria	NOUN
easat-267	33	20	up	up	ADP
easat-267	33	21	to	to	ADP
easat-267	33	22	the	the	DET
easat-267	33	23	end	end	NOUN
easat-267	33	24	of	of	ADP
easat-267	33	25	2016	2016	NUM
easat-267	33	26	.	.	PUNCT
easat-267	34	1	in	in	ADP
easat-267	34	2	2016	2016	NUM
easat-267	34	3	,	,	PUNCT
easat-267	34	4	an	an	DET
easat-267	34	5	estimated	estimate	VERB
easat-267	34	6	216	216	NUM
easat-267	34	7	million	million	NUM
easat-267	34	8	cases	case	NOUN
easat-267	34	9	of	of	ADP
easat-267	34	10	malaria	malaria	NOUN
easat-267	34	11	occurred	occur	VERB
easat-267	34	12	worldwide	worldwide	ADV
easat-267	34	13	.	.	PUNCT
easat-267	35	1	most	most	ADJ
easat-267	35	2	malaria	malaria	ADJ
easat-267	35	3	cases	case	NOUN
easat-267	35	4	in	in	ADP
easat-267	35	5	2016	2016	NUM
easat-267	35	6	were	be	AUX
easat-267	35	7	in	in	ADP
easat-267	35	8	the	the	DET
easat-267	35	9	world	world	NOUN
easat-267	35	10	health	health	NOUN
easat-267	35	11	organization	organization	NOUN
easat-267	35	12	(	(	PUNCT
easat-267	35	13	who	who	PRON
easat-267	35	14	)	)	PUNCT
easat-267	35	15	african	african	ADJ
easat-267	35	16	region	region	NOUN
easat-267	35	17	(	(	PUNCT
easat-267	35	18	90	90	NUM
easat-267	35	19	%	%	NOUN
easat-267	35	20	)	)	PUNCT
easat-267	35	21	,	,	PUNCT
easat-267	35	22	followed	follow	VERB
easat-267	35	23	by	by	ADP
easat-267	35	24	the	the	DET
easat-267	35	25	who	who	PRON
easat-267	35	26	south	south	PROPN
easat-267	35	27	-	-	PUNCT
easat-267	35	28	east	east	PROPN
easat-267	35	29	asia	asia	PROPN
easat-267	35	30	region	region	NOUN
easat-267	35	31	(	(	PUNCT
easat-267	35	32	7	7	NUM
easat-267	35	33	%	%	NOUN
easat-267	35	34	)	)	PUNCT
easat-267	35	35	and	and	CCONJ
easat-267	35	36	the	the	PRON
easat-267	35	37	who	who	PRON
easat-267	35	38	eastern	eastern	ADJ
easat-267	35	39	mediterranean	mediterranean	PROPN
easat-267	35	40	region	region	NOUN
easat-267	35	41	(	(	PUNCT
easat-267	35	42	2	2	NUM
easat-267	35	43	%	%	NOUN
easat-267	35	44	)	)	PUNCT
easat-267	35	45	and	and	CCONJ
easat-267	35	46	the	the	DET
easat-267	35	47	like	like	ADJ
easat-267	35	48	.	.	PUNCT
easat-267	36	1	plasmodium	plasmodium	NOUN
easat-267	36	2	falciparum	falciparum	NOUN
easat-267	36	3	is	be	AUX
easat-267	36	4	the	the	DET
easat-267	36	5	most	most	ADV
easat-267	36	6	prevalent	prevalent	ADJ
easat-267	36	7	malaria	malaria	NOUN
easat-267	36	8	parasite	parasite	NOUN
easat-267	36	9	in	in	ADP
easat-267	36	10	subsaharan	subsaharan	PROPN
easat-267	36	11	africa	africa	PROPN
easat-267	36	12	,	,	PUNCT
easat-267	36	13	accounting	account	VERB
easat-267	36	14	for	for	ADP
easat-267	36	15	99	99	NUM
easat-267	36	16	%	%	NOUN
easat-267	36	17	of	of	ADP
easat-267	36	18	estimated	estimate	VERB
easat-267	36	19	malaria	malaria	NOUN
easat-267	36	20	cases	case	NOUN
easat-267	36	21	in	in	ADP
easat-267	36	22	2016	2016	NUM
easat-267	36	23	.	.	PUNCT
easat-267	37	1	in	in	ADP
easat-267	37	2	2016	2016	NUM
easat-267	37	3	,	,	PUNCT
easat-267	37	4	there	there	PRON
easat-267	37	5	were	be	VERB
easat-267	37	6	an	an	DET
easat-267	37	7	estimated	estimate	VERB
easat-267	37	8	445,000	445,000	NUM
easat-267	37	9	deaths	death	NOUN
easat-267	37	10	from	from	ADP
easat-267	37	11	45	45	NUM
easat-267	37	12	edelweiss	edelweiss	PROPN
easat-267	37	13	applied	apply	VERB
easat-267	37	14	science	science	NOUN
easat-267	37	15	and	and	CCONJ
easat-267	37	16	technology	technology	NOUN
easat-267	37	17	issn	issn	PROPN
easat-267	37	18	:	:	PUNCT
easat-267	37	19	2576	2576	NUM
easat-267	37	20	-	-	SYM
easat-267	37	21	8484	8484	NUM
easat-267	37	22	vol	vol	NOUN
easat-267	37	23	.	.	PROPN
easat-267	38	1	3	3	NUM
easat-267	38	2	,	,	PUNCT
easat-267	38	3	no	no	INTJ
easat-267	38	4	.	.	NOUN
easat-267	38	5	1	1	NUM
easat-267	38	6	:	:	SYM
easat-267	38	7	44	44	NUM
easat-267	38	8	-	-	SYM
easat-267	38	9	52	52	NUM
easat-267	38	10	,	,	PUNCT
easat-267	38	11	2019	2019	NUM
easat-267	38	12	doi	doi	NOUN
easat-267	38	13	:	:	PUNCT
easat-267	38	14	10.33805/2576	10.33805/2576	NUM
easat-267	38	15	-	-	SYM
easat-267	38	16	8484.167	8484.167	NUM
easat-267	38	17	©	©	PROPN
easat-267	38	18	2019	2019	NUM
easat-267	38	19	by	by	ADP
easat-267	38	20	the	the	DET
easat-267	38	21	author	author	NOUN
easat-267	38	22	malaria	malaria	NOUN
easat-267	38	23	globally	globally	ADV
easat-267	38	24	.	.	PUNCT
easat-267	39	1	about	about	ADV
easat-267	39	2	2	2	NUM
easat-267	39	3	million	million	NUM
easat-267	39	4	confirmed	confirm	VERB
easat-267	39	5	malaria	malaria	NOUN
easat-267	39	6	cases	case	NOUN
easat-267	39	7	and	and	CCONJ
easat-267	39	8	1,000	1,000	NUM
easat-267	39	9	deaths	death	NOUN
easat-267	39	10	are	be	AUX
easat-267	39	11	reported	report	VERB
easat-267	39	12	annually	annually	ADV
easat-267	39	13	,	,	PUNCT
easat-267	39	14	although	although	SCONJ
easat-267	39	15	15	15	NUM
easat-267	39	16	million	million	NUM
easat-267	39	17	cases	case	NOUN
easat-267	39	18	and	and	CCONJ
easat-267	39	19	20,000	20,000	NUM
easat-267	39	20	deaths	death	NOUN
easat-267	39	21	are	be	AUX
easat-267	39	22	estimated	estimate	VERB
easat-267	39	23	by	by	ADP
easat-267	39	24	who	who	PRON
easat-267	39	25	south	south	PROPN
easat-267	39	26	east	east	PROPN
easat-267	39	27	asia	asia	PROPN
easat-267	39	28	regional	regional	PROPN
easat-267	39	29	office	office	NOUN
easat-267	39	30	.	.	PUNCT
easat-267	40	1	india	india	PROPN
easat-267	40	2	contributes	contribute	VERB
easat-267	40	3	77	77	NUM
easat-267	40	4	%	%	NOUN
easat-267	40	5	of	of	ADP
easat-267	40	6	the	the	DET
easat-267	40	7	total	total	ADJ
easat-267	40	8	malaria	malaria	NOUN
easat-267	40	9	in	in	ADP
easat-267	40	10	southeast	southeast	PROPN
easat-267	40	11	asia	asia	PROPN
easat-267	40	12	.	.	PUNCT
easat-267	41	1	india	india	PROPN
easat-267	41	2	was	be	AUX
easat-267	41	3	fourth	fourth	ADJ
easat-267	41	4	with	with	ADP
easat-267	41	5	7	7	NUM
easat-267	41	6	percent	percent	NOUN
easat-267	41	7	of	of	ADP
easat-267	41	8	deaths	death	NOUN
easat-267	41	9	,	,	PUNCT
easat-267	41	10	after	after	ADP
easat-267	41	11	nigeria	nigeria	X
easat-267	41	12	(	(	PUNCT
easat-267	41	13	30	30	NUM
easat-267	41	14	%	%	NOUN
easat-267	41	15	)	)	PUNCT
easat-267	41	16	,	,	PUNCT
easat-267	41	17	the	the	DET
easat-267	41	18	democratic	democratic	PROPN
easat-267	41	19	republic	republic	PROPN
easat-267	41	20	of	of	ADP
easat-267	41	21	congo	congo	PROPN
easat-267	41	22	(	(	PUNCT
easat-267	41	23	14	14	NUM
easat-267	41	24	%	%	NOUN
easat-267	41	25	)	)	PUNCT
easat-267	41	26	,	,	PUNCT
easat-267	41	27	burkina	burkina	PROPN
easat-267	41	28	faso	faso	PROPN
easat-267	41	29	(	(	PUNCT
easat-267	41	30	7	7	NUM
easat-267	41	31	%	%	NOUN
easat-267	41	32	)	)	PUNCT
easat-267	41	33	and	and	CCONJ
easat-267	41	34	so	so	ADV
easat-267	41	35	on	on	ADP
easat-267	41	36	[	[	X
easat-267	41	37	3	3	NUM
easat-267	41	38	]	]	PUNCT
easat-267	41	39	.	.	PUNCT
easat-267	42	1	malaria	malaria	NOUN
easat-267	42	2	is	be	AUX
easat-267	42	3	one	one	NUM
easat-267	42	4	of	of	ADP
easat-267	42	5	the	the	DET
easat-267	42	6	leading	lead	VERB
easat-267	42	7	causes	cause	NOUN
easat-267	42	8	of	of	ADP
easat-267	42	9	death	death	NOUN
easat-267	42	10	worldwide	worldwide	ADV
easat-267	42	11	and	and	CCONJ
easat-267	42	12	genes	gene	NOUN
easat-267	42	13	involved	involve	VERB
easat-267	42	14	in	in	ADP
easat-267	42	15	malaria	malaria	NOUN
easat-267	42	16	resistance	resistance	NOUN
easat-267	42	17	are	be	AUX
easat-267	42	18	the	the	DET
easat-267	42	19	most	most	ADV
easat-267	42	20	important	important	ADJ
easat-267	42	21	for	for	ADP
easat-267	42	22	the	the	DET
easat-267	42	23	natural	natural	ADJ
easat-267	42	24	selection	selection	NOUN
easat-267	42	25	in	in	ADP
easat-267	42	26	human	human	ADJ
easat-267	42	27	populations	population	NOUN
easat-267	42	28	.	.	PUNCT
easat-267	43	1	in	in	ADP
easat-267	43	2	1949	1949	NUM
easat-267	43	3	,	,	PUNCT
easat-267	43	4	haldane	haldane	PROPN
easat-267	43	5	suggested	suggest	VERB
easat-267	43	6	that	that	SCONJ
easat-267	43	7	infectious	infectious	ADJ
easat-267	43	8	disease	disease	NOUN
easat-267	43	9	could	could	AUX
easat-267	43	10	be	be	AUX
easat-267	43	11	a	a	DET
easat-267	43	12	strong	strong	ADJ
easat-267	43	13	selective	selective	ADJ
easat-267	43	14	force	force	NOUN
easat-267	43	15	in	in	ADP
easat-267	43	16	human	human	ADJ
easat-267	43	17	populations	population	NOUN
easat-267	43	18	[	[	X
easat-267	43	19	4	4	NUM
easat-267	43	20	]	]	PUNCT
easat-267	43	21	.	.	PUNCT
easat-267	44	1	evidence	evidence	NOUN
easat-267	44	2	for	for	ADP
easat-267	44	3	the	the	DET
easat-267	44	4	strong	strong	ADJ
easat-267	44	5	selective	selective	ADJ
easat-267	44	6	effect	effect	NOUN
easat-267	44	7	of	of	ADP
easat-267	44	8	malaria	malaria	NOUN
easat-267	44	9	resistance	resistance	NOUN
easat-267	44	10	includes	include	VERB
easat-267	44	11	the	the	DET
easat-267	44	12	high	high	ADJ
easat-267	44	13	frequency	frequency	NOUN
easat-267	44	14	of	of	ADP
easat-267	44	15	a	a	DET
easat-267	44	16	number	number	NOUN
easat-267	44	17	of	of	ADP
easat-267	44	18	detrimental	detrimental	ADJ
easat-267	44	19	hemato	hemato	NOUN
easat-267	44	20	-	-	PUNCT
easat-267	44	21	genetic	genetic	ADJ
easat-267	44	22	diseases	disease	NOUN
easat-267	44	23	(	(	PUNCT
easat-267	44	24	including	include	VERB
easat-267	44	25	the	the	DET
easat-267	44	26	different	different	ADJ
easat-267	44	27	hemoglobinopathies	hemoglobinopathy	NOUN
easat-267	44	28	,	,	PUNCT
easat-267	44	29	thalassemias	thalassemia	NOUN
easat-267	44	30	,	,	PUNCT
easat-267	44	31	and	and	CCONJ
easat-267	44	32	red	red	ADJ
easat-267	44	33	cell	cell	NOUN
easat-267	44	34	enzymopathy	enzymopathy	ADJ
easat-267	44	35	)	)	PUNCT
easat-267	44	36	,	,	PUNCT
easat-267	44	37	caused	cause	VERB
easat-267	44	38	by	by	ADP
easat-267	44	39	the	the	DET
easat-267	44	40	effects	effect	NOUN
easat-267	44	41	of	of	ADP
easat-267	44	42	these	these	DET
easat-267	44	43	malaria	malaria	ADJ
easat-267	44	44	resistance	resistance	NOUN
easat-267	44	45	variants	variant	NOUN
easat-267	44	46	.	.	PUNCT
easat-267	45	1	in	in	ADP
easat-267	45	2	view	view	NOUN
easat-267	45	3	of	of	ADP
easat-267	45	4	this	this	DET
easat-267	45	5	pathetic	pathetic	ADJ
easat-267	45	6	scenario	scenario	NOUN
easat-267	45	7	,	,	PUNCT
easat-267	45	8	it	it	PRON
easat-267	45	9	is	be	AUX
easat-267	45	10	justifiable	justifiable	ADJ
easat-267	45	11	that	that	SCONJ
easat-267	45	12	population	population	NOUN
easat-267	45	13	genetics	genetic	NOUN
easat-267	45	14	could	could	AUX
easat-267	45	15	be	be	AUX
easat-267	45	16	useful	useful	ADJ
easat-267	45	17	to	to	PART
easat-267	45	18	determine	determine	VERB
easat-267	45	19	the	the	DET
easat-267	45	20	amount	amount	NOUN
easat-267	45	21	and	and	CCONJ
easat-267	45	22	pattern	pattern	NOUN
easat-267	45	23	of	of	ADP
easat-267	45	24	natural	natural	ADJ
easat-267	45	25	selection	selection	NOUN
easat-267	45	26	in	in	ADP
easat-267	45	27	human	human	ADJ
easat-267	45	28	population	population	NOUN
easat-267	45	29	isolates	isolate	VERB
easat-267	45	30	[	[	X
easat-267	45	31	512	512	NUM
easat-267	45	32	]	]	PUNCT
easat-267	45	33	.	.	PUNCT
easat-267	46	1	1.2	1.2	NUM
easat-267	46	2	.	.	PUNCT
easat-267	46	3	human	human	ADJ
easat-267	46	4	red	red	ADJ
easat-267	46	5	cell	cell	NOUN
easat-267	46	6	genetic	genetic	ADJ
easat-267	46	7	variants	variant	NOUN
easat-267	46	8	and	and	CCONJ
easat-267	46	9	plasmodium	plasmodium	NOUN
easat-267	46	10	falciparum	falciparum	ADJ
easat-267	46	11	malaria	malaria	NOUN
easat-267	46	12	red	red	ADJ
easat-267	46	13	cell	cell	NOUN
easat-267	46	14	variants	variant	NOUN
easat-267	46	15	that	that	PRON
easat-267	46	16	modulate	modulate	VERB
easat-267	46	17	malaria	malaria	NOUN
easat-267	46	18	risk	risk	NOUN
easat-267	46	19	can	can	AUX
easat-267	46	20	serve	serve	VERB
easat-267	46	21	as	as	ADP
easat-267	46	22	models	model	NOUN
easat-267	46	23	to	to	PART
easat-267	46	24	identify	identify	VERB
easat-267	46	25	clinically	clinically	ADV
easat-267	46	26	relevant	relevant	ADJ
easat-267	46	27	mechanisms	mechanism	NOUN
easat-267	46	28	of	of	ADP
easat-267	46	29	pathogenesis	pathogenesis	NOUN
easat-267	46	30	,	,	PUNCT
easat-267	46	31	and	and	CCONJ
easat-267	46	32	thus	thus	ADV
easat-267	46	33	define	define	VERB
easat-267	46	34	parasite	parasite	NOUN
easat-267	46	35	and	and	CCONJ
easat-267	46	36	host	host	NOUN
easat-267	46	37	targets	target	NOUN
easat-267	46	38	for	for	ADP
easat-267	46	39	next	next	ADJ
easat-267	46	40	-	-	PUNCT
easat-267	46	41	generation	generation	NOUN
easat-267	46	42	therapies	therapy	NOUN
easat-267	46	43	.	.	PUNCT
easat-267	47	1	multiple	multiple	ADJ
easat-267	47	2	red	red	ADJ
easat-267	47	3	cell	cell	NOUN
easat-267	47	4	variants	variant	NOUN
easat-267	47	5	are	be	AUX
easat-267	47	6	known	know	VERB
easat-267	47	7	to	to	PART
easat-267	47	8	confer	confer	VERB
easat-267	47	9	protection	protection	NOUN
easat-267	47	10	from	from	ADP
easat-267	47	11	malaria	malaria	NOUN
easat-267	47	12	.	.	PUNCT
easat-267	48	1	from	from	ADP
easat-267	48	2	a	a	DET
easat-267	48	3	biological	biological	ADJ
easat-267	48	4	point	point	NOUN
easat-267	48	5	-	-	PUNCT
easat-267	48	6	of	of	ADP
easat-267	48	7	-	-	PUNCT
easat-267	48	8	view	view	NOUN
easat-267	48	9	,	,	PUNCT
easat-267	48	10	these	these	DET
easat-267	48	11	insights	insight	NOUN
easat-267	48	12	highlight	highlight	VERB
easat-267	48	13	the	the	DET
easat-267	48	14	co	co	NOUN
easat-267	48	15	-	-	NOUN
easat-267	48	16	evolution	evolution	NOUN
easat-267	48	17	of	of	ADP
easat-267	48	18	host	host	NOUN
easat-267	48	19	and	and	CCONJ
easat-267	48	20	parasite	parasite	NOUN
easat-267	48	21	and	and	CCONJ
easat-267	48	22	serve	serve	VERB
easat-267	48	23	as	as	ADP
easat-267	48	24	a	a	DET
easat-267	48	25	model	model	NOUN
easat-267	48	26	of	of	ADP
easat-267	48	27	balancing	balance	VERB
easat-267	48	28	selection	selection	NOUN
easat-267	48	29	.	.	PUNCT
easat-267	49	1	from	from	ADP
easat-267	49	2	a	a	DET
easat-267	49	3	clinical	clinical	ADJ
easat-267	49	4	perspective	perspective	NOUN
easat-267	49	5	,	,	PUNCT
easat-267	49	6	these	these	DET
easat-267	49	7	relationships	relationship	NOUN
easat-267	49	8	represent	represent	VERB
easat-267	49	9	a	a	DET
easat-267	49	10	naturally	naturally	ADV
easat-267	49	11	occurring	occur	VERB
easat-267	49	12	model	model	NOUN
easat-267	49	13	of	of	ADP
easat-267	49	14	protection	protection	NOUN
easat-267	49	15	from	from	ADP
easat-267	49	16	severe	severe	ADJ
easat-267	49	17	,	,	PUNCT
easat-267	49	18	life	life	NOUN
easat-267	49	19	threatening	threaten	VERB
easat-267	49	20	malaria	malaria	NOUN
easat-267	49	21	,	,	PUNCT
easat-267	49	22	which	which	PRON
easat-267	49	23	can	can	AUX
easat-267	49	24	be	be	AUX
easat-267	49	25	used	use	VERB
easat-267	49	26	to	to	PART
easat-267	49	27	isolate	isolate	VERB
easat-267	49	28	the	the	DET
easat-267	49	29	mechanisms	mechanism	NOUN
easat-267	49	30	of	of	ADP
easat-267	49	31	parasite	parasite	ADJ
easat-267	49	32	pathogenes	pathogene	NOUN
easat-267	49	33	is	be	AUX
easat-267	49	34	.	.	PUNCT
easat-267	50	1	by	by	ADP
easat-267	50	2	preventing	prevent	VERB
easat-267	50	3	malaria	malaria	NOUN
easat-267	50	4	parasites	parasite	NOUN
easat-267	50	5	from	from	ADP
easat-267	50	6	causing	cause	VERB
easat-267	50	7	disease	disease	NOUN
easat-267	50	8	,	,	PUNCT
easat-267	50	9	these	these	DET
easat-267	50	10	red	red	ADJ
easat-267	50	11	cell	cell	NOUN
easat-267	50	12	variants	variant	NOUN
easat-267	50	13	could	could	AUX
easat-267	50	14	help	help	VERB
easat-267	50	15	discover	discover	VERB
easat-267	50	16	clinically	clinically	ADV
easat-267	50	17	significant	significant	ADJ
easat-267	50	18	mechanism(s	mechanism(s	NOUN
easat-267	50	19	)	)	PUNCT
easat-267	50	20	of	of	ADP
easat-267	50	21	pathogenesis	pathogenesis	NOUN
easat-267	50	22	and	and	CCONJ
easat-267	50	23	investigating	investigate	VERB
easat-267	50	24	them	they	PRON
easat-267	50	25	as	as	ADP
easat-267	50	26	targets	target	NOUN
easat-267	50	27	for	for	ADP
easat-267	50	28	future	future	ADJ
easat-267	50	29	therapeutics	therapeutic	NOUN
easat-267	50	30	.	.	PUNCT
easat-267	51	1	1.3	1.3	NUM
easat-267	51	2	.	.	PUNCT
easat-267	52	1	thalassemia	thalassemia	PROPN
easat-267	52	2	jbs	jbs	PROPN
easat-267	52	3	haldane	haldane	PROPN
easat-267	52	4	was	be	AUX
easat-267	52	5	the	the	DET
easat-267	52	6	first	first	ADJ
easat-267	52	7	who	who	PRON
easat-267	52	8	speculated	speculate	VERB
easat-267	52	9	the	the	DET
easat-267	52	10	darwinian	darwinian	PROPN
easat-267	52	11	(	(	PUNCT
easat-267	52	12	natural	natural	ADJ
easat-267	52	13	)	)	PUNCT
easat-267	52	14	selection	selection	NOUN
easat-267	52	15	that	that	PRON
easat-267	52	16	,	,	PUNCT
easat-267	52	17	depending	depend	VERB
easat-267	52	18	on	on	ADP
easat-267	52	19	the	the	DET
easat-267	52	20	genetic	genetic	ADJ
easat-267	52	21	make	make	NOUN
easat-267	52	22	-	-	PUNCT
easat-267	52	23	up	up	NOUN
easat-267	52	24	,	,	PUNCT
easat-267	52	25	the	the	DET
easat-267	52	26	people	people	NOUN
easat-267	52	27	would	would	AUX
easat-267	52	28	have	have	VERB
easat-267	52	29	a	a	DET
easat-267	52	30	different	different	ADJ
easat-267	52	31	risk	risk	NOUN
easat-267	52	32	of	of	ADP
easat-267	52	33	dying	die	VERB
easat-267	52	34	when	when	SCONJ
easat-267	52	35	they	they	PRON
easat-267	52	36	are	be	AUX
easat-267	52	37	confronted	confront	VERB
easat-267	52	38	by	by	ADP
easat-267	52	39	a	a	DET
easat-267	52	40	parasitic	parasitic	ADJ
easat-267	52	41	organism	organism	NOUN
easat-267	52	42	;	;	PUNCT
easat-267	52	43	so	so	ADV
easat-267	52	44	much	much	ADV
easat-267	52	45	so	so	SCONJ
easat-267	52	46	that	that	SCONJ
easat-267	52	47	,	,	PUNCT
easat-267	52	48	even	even	ADV
easat-267	52	49	if	if	SCONJ
easat-267	52	50	,	,	PUNCT
easat-267	52	51	a	a	DET
easat-267	52	52	gene	gene	NOUN
easat-267	52	53	offering	offer	VERB
easat-267	52	54	protection	protection	NOUN
easat-267	52	55	against	against	ADP
easat-267	52	56	those	those	DET
easat-267	52	57	parasites	parasite	NOUN
easat-267	52	58	were	be	AUX
easat-267	52	59	,	,	PUNCT
easat-267	52	60	otherwise	otherwise	ADV
easat-267	52	61	,	,	PUNCT
easat-267	52	62	harmful	harmful	ADJ
easat-267	52	63	,	,	PUNCT
easat-267	52	64	its	its	PRON
easat-267	52	65	frequency	frequency	NOUN
easat-267	52	66	would	would	AUX
easat-267	52	67	increase	increase	VERB
easat-267	52	68	when	when	SCONJ
easat-267	52	69	a	a	DET
easat-267	52	70	population	population	NOUN
easat-267	52	71	was	be	AUX
easat-267	52	72	exposed	expose	VERB
easat-267	52	73	to	to	ADP
easat-267	52	74	the	the	DET
easat-267	52	75	parasites	parasite	NOUN
easat-267	52	76	[	[	X
easat-267	52	77	4,13	4,13	X
easat-267	52	78	]	]	PUNCT
easat-267	52	79	.	.	PUNCT
easat-267	53	1	later	later	ADV
easat-267	53	2	,	,	PUNCT
easat-267	53	3	haldane	haldane	PROPN
easat-267	53	4	hypothesized	hypothesize	VERB
easat-267	53	5	that	that	SCONJ
easat-267	53	6	one	one	NUM
easat-267	53	7	important	important	ADJ
easat-267	53	8	example	example	NOUN
easat-267	53	9	could	could	AUX
easat-267	53	10	be	be	AUX
easat-267	53	11	of	of	ADP
easat-267	53	12	thalassemia	thalassemia	NOUN
easat-267	53	13	in	in	ADP
easat-267	53	14	the	the	DET
easat-267	53	15	face	face	NOUN
easat-267	53	16	of	of	ADP
easat-267	53	17	malaria	malaria	NOUN
easat-267	53	18	for	for	ADP
easat-267	53	19	several	several	ADJ
easat-267	53	20	reasons	reason	NOUN
easat-267	53	21	.	.	PUNCT
easat-267	54	1	first	first	ADV
easat-267	54	2	,	,	PUNCT
easat-267	54	3	one	one	NUM
easat-267	54	4	type	type	NOUN
easat-267	54	5	of	of	ADP
easat-267	54	6	malaria	malaria	NOUN
easat-267	54	7	,	,	PUNCT
easat-267	54	8	caused	cause	VERB
easat-267	54	9	by	by	ADP
easat-267	54	10	plasmodium	plasmodium	NOUN
easat-267	54	11	falciparum	falciparum	NOUN
easat-267	54	12	,	,	PUNCT
easat-267	54	13	is	be	AUX
easat-267	54	14	highly	highly	ADV
easat-267	54	15	lethal	lethal	ADJ
easat-267	54	16	.	.	PUNCT
easat-267	55	1	second	second	ADJ
easat-267	55	2	,	,	PUNCT
easat-267	55	3	it	it	PRON
easat-267	55	4	is	be	AUX
easat-267	55	5	estimated	estimate	VERB
easat-267	55	6	to	to	PART
easat-267	55	7	have	have	AUX
easat-267	55	8	been	be	AUX
easat-267	55	9	spread	spread	VERB
easat-267	55	10	in	in	ADP
easat-267	55	11	many	many	ADJ
easat-267	55	12	parts	part	NOUN
easat-267	55	13	of	of	ADP
easat-267	55	14	the	the	DET
easat-267	55	15	world	world	NOUN
easat-267	55	16	for	for	ADP
easat-267	55	17	several	several	ADJ
easat-267	55	18	thousands	thousand	NOUN
easat-267	55	19	of	of	ADP
easat-267	55	20	years	year	NOUN
easat-267	55	21	,	,	PUNCT
easat-267	55	22	i.e.	i.e.	X
easat-267	55	23	for	for	ADP
easat-267	55	24	several	several	ADJ
easat-267	55	25	hundreds	hundred	NOUN
easat-267	55	26	of	of	ADP
easat-267	55	27	generations	generation	NOUN
easat-267	55	28	;	;	PUNCT
easat-267	55	29	thus	thus	ADV
easat-267	55	30	,	,	PUNCT
easat-267	55	31	malaria	malaria	NOUN
easat-267	55	32	as	as	ADP
easat-267	55	33	an	an	DET
easat-267	55	34	agent	agent	NOUN
easat-267	55	35	of	of	ADP
easat-267	55	36	natural	natural	ADJ
easat-267	55	37	selection	selection	NOUN
easat-267	55	38	seemed	seem	VERB
easat-267	55	39	to	to	PART
easat-267	55	40	be	be	AUX
easat-267	55	41	a	a	DET
easat-267	55	42	better	well	ADJ
easat-267	55	43	candidate	candidate	NOUN
easat-267	55	44	than	than	ADP
easat-267	55	45	an	an	DET
easat-267	55	46	infectious	infectious	ADJ
easat-267	55	47	disease	disease	NOUN
easat-267	55	48	,	,	PUNCT
easat-267	55	49	causing	cause	VERB
easat-267	55	50	occasional	occasional	ADJ
easat-267	55	51	epidemics	epidemic	NOUN
easat-267	55	52	,	,	PUNCT
easat-267	55	53	even	even	ADV
easat-267	55	54	if	if	SCONJ
easat-267	55	55	associated	associate	VERB
easat-267	55	56	with	with	ADP
easat-267	55	57	high	high	ADJ
easat-267	55	58	mortality	mortality	NOUN
easat-267	55	59	(	(	PUNCT
easat-267	55	60	such	such	ADJ
easat-267	55	61	as	as	ADP
easat-267	55	62	influenza	influenza	NOUN
easat-267	55	63	or	or	CCONJ
easat-267	55	64	aids	aid	NOUN
easat-267	55	65	)	)	PUNCT
easat-267	55	66	.	.	PUNCT
easat-267	56	1	third	third	ADJ
easat-267	56	2	,	,	PUNCT
easat-267	56	3	deaths	death	NOUN
easat-267	56	4	from	from	ADP
easat-267	56	5	malaria	malaria	NOUN
easat-267	56	6	take	take	NOUN
easat-267	56	7	place	place	NOUN
easat-267	56	8	mostly	mostly	ADV
easat-267	56	9	in	in	ADP
easat-267	56	10	children	child	NOUN
easat-267	56	11	,	,	PUNCT
easat-267	56	12	i.e.	i.e.	X
easat-267	56	13	before	before	ADP
easat-267	56	14	reproduction	reproduction	NOUN
easat-267	56	15	,	,	PUNCT
easat-267	56	16	a	a	DET
easat-267	56	17	critical	critical	ADJ
easat-267	56	18	criterion	criterion	NOUN
easat-267	56	19	for	for	ADP
easat-267	56	20	effective	effective	ADJ
easat-267	56	21	selection	selection	NOUN
easat-267	56	22	.	.	PUNCT
easat-267	57	1	last	last	ADJ
easat-267	57	2	but	but	CCONJ
easat-267	57	3	not	not	PART
easat-267	57	4	the	the	DET
easat-267	57	5	least	least	ADJ
easat-267	57	6	,	,	PUNCT
easat-267	57	7	plasmodia	plasmodia	NOUN
easat-267	57	8	take	take	VERB
easat-267	57	9	on	on	ADP
easat-267	57	10	different	different	ADJ
easat-267	57	11	forms	form	NOUN
easat-267	57	12	in	in	ADP
easat-267	57	13	the	the	DET
easat-267	57	14	course	course	NOUN
easat-267	57	15	of	of	ADP
easat-267	57	16	their	their	PRON
easat-267	57	17	life	life	NOUN
easat-267	57	18	cycle	cycle	NOUN
easat-267	57	19	,	,	PUNCT
easat-267	57	20	but	but	CCONJ
easat-267	57	21	what	what	PRON
easat-267	57	22	causes	cause	VERB
easat-267	57	23	a	a	DET
easat-267	57	24	disease	disease	NOUN
easat-267	57	25	,	,	PUNCT
easat-267	57	26	are	be	AUX
easat-267	57	27	the	the	DET
easat-267	57	28	intra	intra	ADJ
easat-267	57	29	-	-	ADJ
easat-267	57	30	erythrocyte	erythrocyte	ADJ
easat-267	57	31	parasites	parasite	NOUN
easat-267	57	32	.	.	PUNCT
easat-267	58	1	therefore	therefore	ADV
easat-267	58	2	,	,	PUNCT
easat-267	58	3	in	in	ADP
easat-267	58	4	principle	principle	NOUN
easat-267	58	5	,	,	PUNCT
easat-267	58	6	it	it	PRON
easat-267	58	7	is	be	AUX
easat-267	58	8	not	not	PART
easat-267	58	9	surprising	surprising	ADJ
easat-267	58	10	that	that	SCONJ
easat-267	58	11	,	,	PUNCT
easat-267	58	12	if	if	SCONJ
easat-267	58	13	red	red	ADJ
easat-267	58	14	cells	cell	NOUN
easat-267	58	15	are	be	AUX
easat-267	58	16	in	in	ADP
easat-267	58	17	any	any	DET
easat-267	58	18	way	way	NOUN
easat-267	58	19	abnormal	abnormal	ADJ
easat-267	58	20	(	(	PUNCT
easat-267	58	21	as	as	SCONJ
easat-267	58	22	they	they	PRON
easat-267	58	23	are	be	AUX
easat-267	58	24	,	,	PUNCT
easat-267	58	25	for	for	ADP
easat-267	58	26	instance	instance	NOUN
easat-267	58	27	,	,	PUNCT
easat-267	58	28	in	in	ADP
easat-267	58	29	thalassemia	thalassemia	NOUN
easat-267	58	30	)	)	PUNCT
easat-267	58	31	,	,	PUNCT
easat-267	58	32	they	they	PRON
easat-267	58	33	may	may	AUX
easat-267	58	34	affect	affect	VERB
easat-267	58	35	the	the	DET
easat-267	58	36	chance	chance	NOUN
easat-267	58	37	of	of	ADP
easat-267	58	38	success	success	NOUN
easat-267	58	39	of	of	ADP
easat-267	58	40	the	the	DET
easat-267	58	41	parasites	parasite	NOUN
easat-267	58	42	[	[	X
easat-267	58	43	14	14	NUM
easat-267	58	44	]	]	PUNCT
easat-267	58	45	.	.	PUNCT
easat-267	59	1	similarly	similarly	ADV
easat-267	59	2	,	,	PUNCT
easat-267	59	3	alpha	alpha	NOUN
easat-267	59	4	(	(	PUNCT
easat-267	59	5	α+)-thalassemia	α+)-thalassemia	PROPN
easat-267	59	6	,	,	PUNCT
easat-267	59	7	being	be	AUX
easat-267	59	8	very	very	ADV
easat-267	59	9	common	common	ADJ
easat-267	59	10	in	in	ADP
easat-267	59	11	malaria	malaria	ADJ
easat-267	59	12	endemic	endemic	ADJ
easat-267	59	13	regions	region	NOUN
easat-267	59	14	,	,	PUNCT
easat-267	59	15	it	it	PRON
easat-267	59	16	has	have	AUX
easat-267	59	17	been	be	AUX
easat-267	59	18	considered	consider	VERB
easat-267	59	19	to	to	PART
easat-267	59	20	confer	confer	VERB
easat-267	59	21	protection	protection	NOUN
easat-267	59	22	against	against	ADP
easat-267	59	23	clinical	clinical	ADJ
easat-267	59	24	disease	disease	NOUN
easat-267	59	25	caused	cause	VERB
easat-267	59	26	by	by	ADP
easat-267	59	27	severe	severe	ADJ
easat-267	59	28	forms	form	NOUN
easat-267	59	29	of	of	ADP
easat-267	59	30	plasmodium	plasmodium	NOUN
easat-267	59	31	falciparum	falciparum	ADJ
easat-267	59	32	malaria	malaria	NOUN
easat-267	59	33	infection	infection	NOUN
easat-267	59	34	.	.	PUNCT
easat-267	60	1	in	in	ADP
easat-267	60	2	the	the	DET
easat-267	60	3	same	same	ADJ
easat-267	60	4	way	way	NOUN
easat-267	60	5	,	,	PUNCT
easat-267	60	6	beta	beta	NOUN
easat-267	60	7	(	(	PUNCT
easat-267	60	8	β+)-thalassemia	β+)-thalassemia	NOUN
easat-267	60	9	provides	provide	VERB
easat-267	60	10	protection	protection	NOUN
easat-267	60	11	against	against	ADP
easat-267	60	12	the	the	DET
easat-267	60	13	plasmodium	plasmodium	NOUN
easat-267	60	14	falciparum	falciparum	ADJ
easat-267	60	15	malaria	malaria	NOUN
easat-267	60	16	with	with	ADP
easat-267	60	17	significantly	significantly	ADV
easat-267	60	18	lower	low	ADJ
easat-267	60	19	growth	growth	NOUN
easat-267	60	20	of	of	ADP
easat-267	60	21	malaria	malaria	NOUN
easat-267	60	22	parasite	parasite	NOUN
easat-267	60	23	inside	inside	ADP
easat-267	60	24	the	the	DET
easat-267	60	25	infected	infected	ADJ
easat-267	60	26	erythrocytes	erythrocyte	NOUN
easat-267	60	27	and	and	CCONJ
easat-267	60	28	higher	high	ADJ
easat-267	60	29	phagocytosis	phagocytosis	NOUN
easat-267	60	30	of	of	ADP
easat-267	60	31	β	β	ADJ
easat-267	60	32	-	-	ADJ
easat-267	60	33	thalassemic	thalassemic	ADJ
easat-267	60	34	infected	infect	VERB
easat-267	60	35	erythrocytes	erythrocyte	NOUN
easat-267	60	36	when	when	SCONJ
easat-267	60	37	compared	compare	VERB
easat-267	60	38	to	to	ADP
easat-267	60	39	normal	normal	ADJ
easat-267	60	40	infected	infected	ADJ
easat-267	60	41	erythrocytes	erythrocyte	NOUN
easat-267	60	42	.	.	PUNCT
easat-267	61	1	moreover	moreover	ADV
easat-267	61	2	,	,	PUNCT
easat-267	61	3	the	the	DET
easat-267	61	4	resistance	resistance	NOUN
easat-267	61	5	given	give	VERB
easat-267	61	6	to	to	ADP
easat-267	61	7	malaria	malaria	ADJ
easat-267	61	8	parasite	parasite	NOUN
easat-267	61	9	inside	inside	ADP
easat-267	61	10	the	the	DET
easat-267	61	11	infected	infected	ADJ
easat-267	61	12	erythrocytes	erythrocyte	NOUN
easat-267	61	13	is	be	AUX
easat-267	61	14	almost	almost	ADV
easat-267	61	15	identical	identical	ADJ
easat-267	61	16	to	to	ADP
easat-267	61	17	that	that	PRON
easat-267	61	18	of	of	ADP
easat-267	61	19	sickle	sickle	NOUN
easat-267	61	20	cell	cell	NOUN
easat-267	61	21	trait	trait	NOUN
easat-267	61	22	infected	infect	VERB
easat-267	61	23	erythrocytes	erythrocyte	NOUN
easat-267	61	24	.	.	PUNCT
easat-267	62	1	1.4	1.4	NUM
easat-267	62	2	.	.	PUNCT
easat-267	63	1	sickle	sickle	NOUN
easat-267	63	2	cell	cell	PROPN
easat-267	63	3	anemia	anemia	NOUN
easat-267	63	4	this	this	DET
easat-267	63	5	brief	brief	ADJ
easat-267	63	6	review	review	NOUN
easat-267	63	7	has	have	AUX
easat-267	63	8	been	be	AUX
easat-267	63	9	focused	focus	VERB
easat-267	63	10	on	on	ADP
easat-267	63	11	the	the	DET
easat-267	63	12	close	close	ADJ
easat-267	63	13	and	and	CCONJ
easat-267	63	14	complex	complex	ADJ
easat-267	63	15	relationship	relationship	NOUN
easat-267	63	16	of	of	ADP
easat-267	63	17	blood	blood	NOUN
easat-267	63	18	disease	disease	NOUN
easat-267	63	19	,	,	PUNCT
easat-267	63	20	e.g.	e.g.	ADV
easat-267	63	21	the	the	DET
easat-267	63	22	sickle	sickle	NOUN
easat-267	63	23	cell	cell	NOUN
easat-267	63	24	anemia	anemia	NOUN
easat-267	63	25	(	(	PUNCT
easat-267	63	26	sca	sca	PROPN
easat-267	63	27	)	)	PUNCT
easat-267	63	28	with	with	ADP
easat-267	63	29	infectious	infectious	ADJ
easat-267	63	30	disease	disease	NOUN
easat-267	63	31	of	of	ADP
easat-267	63	32	malaria	malaria	NOUN
easat-267	63	33	.	.	PUNCT
easat-267	64	1	sickle	sickle	NOUN
easat-267	64	2	cell	cell	PROPN
easat-267	64	3	anemia	anemia	NOUN
easat-267	64	4	is	be	AUX
easat-267	64	5	a	a	DET
easat-267	64	6	major	major	ADJ
easat-267	64	7	hemolytic	hemolytic	ADJ
easat-267	64	8	anemia	anemia	NOUN
easat-267	64	9	and	and	CCONJ
easat-267	64	10	its	its	PRON
easat-267	64	11	epidemiology	epidemiology	NOUN
easat-267	64	12	represents	represent	VERB
easat-267	64	13	a	a	DET
easat-267	64	14	remarkable	remarkable	ADJ
easat-267	64	15	signature	signature	NOUN
easat-267	64	16	of	of	ADP
easat-267	64	17	the	the	DET
easat-267	64	18	past	past	NOUN
easat-267	64	19	and	and	CCONJ
easat-267	64	20	present	present	ADJ
easat-267	64	21	world	world	NOUN
easat-267	64	22	distribution	distribution	NOUN
easat-267	64	23	of	of	ADP
easat-267	64	24	plasmodium	plasmodium	NOUN
easat-267	64	25	falciparum	falciparum	ADJ
easat-267	64	26	malaria	malaria	NOUN
easat-267	65	1	[	[	X
easat-267	65	2	14	14	NUM
easat-267	65	3	]	]	PUNCT
easat-267	65	4	.	.	PUNCT
easat-267	66	1	on	on	ADP
easat-267	66	2	one	one	NUM
easat-267	66	3	hand	hand	NOUN
easat-267	66	4	,	,	PUNCT
easat-267	66	5	heterozygotes	heterozygote	NOUN
easat-267	66	6	(	(	PUNCT
easat-267	66	7	hb	hb	X
easat-267	66	8	as	as	ADP
easat-267	66	9	)	)	PUNCT
easat-267	66	10	for	for	ADP
easat-267	66	11	the	the	DET
easat-267	66	12	sickle	sickle	NOUN
easat-267	66	13	gene	gene	NOUN
easat-267	66	14	are	be	AUX
easat-267	66	15	relatively	relatively	ADV
easat-267	66	16	protected	protect	VERB
easat-267	66	17	against	against	ADP
easat-267	66	18	the	the	DET
easat-267	66	19	danger	danger	NOUN
easat-267	66	20	of	of	ADP
easat-267	66	21	dying	die	VERB
easat-267	66	22	with	with	ADP
easat-267	66	23	malaria	malaria	NOUN
easat-267	66	24	as	as	SCONJ
easat-267	66	25	now	now	ADV
easat-267	66	26	firmly	firmly	ADV
easat-267	66	27	established	establish	VERB
easat-267	66	28	through	through	ADP
easat-267	66	29	a	a	DET
easat-267	66	30	number	number	NOUN
easat-267	66	31	of	of	ADP
easat-267	66	32	clinical	clinical	ADJ
easat-267	66	33	field	field	NOUN
easat-267	66	34	studies	study	NOUN
easat-267	66	35	reviewed	review	VERB
easat-267	66	36	from	from	ADP
easat-267	66	37	different	different	ADJ
easat-267	66	38	parts	part	NOUN
easat-267	66	39	of	of	ADP
easat-267	66	40	africa	africa	PROPN
easat-267	66	41	,	,	PUNCT
easat-267	66	42	south	south	PROPN
easat-267	66	43	east	east	PROPN
easat-267	66	44	asia	asia	PROPN
easat-267	66	45	,	,	PUNCT
easat-267	66	46	indian	indian	PROPN
easat-267	66	47	subcontinent	subcontinent	PROPN
easat-267	66	48	,	,	PUNCT
easat-267	66	49	and	and	CCONJ
easat-267	66	50	the	the	DET
easat-267	66	51	middle	middle	PROPN
easat-267	66	52	east	east	PROPN
easat-267	66	53	regions	region	NOUN
easat-267	66	54	[	[	X
easat-267	66	55	11,15	11,15	NUM
easat-267	66	56	-	-	SYM
easat-267	66	57	20	20	NUM
easat-267	66	58	]	]	PUNCT
easat-267	66	59	.	.	PUNCT
easat-267	67	1	in	in	ADP
easat-267	67	2	addition	addition	NOUN
easat-267	67	3	,	,	PUNCT
easat-267	67	4	the	the	DET
easat-267	67	5	experimental	experimental	ADJ
easat-267	67	6	work	work	NOUN
easat-267	67	7	is	be	AUX
easat-267	67	8	consistent	consistent	ADJ
easat-267	67	9	with	with	ADP
easat-267	67	10	the	the	DET
easat-267	67	11	heterozygote	heterozygote	NOUN
easat-267	67	12	(	(	PUNCT
easat-267	67	13	hb	hb	X
easat-267	67	14	as	as	ADP
easat-267	67	15	)	)	PUNCT
easat-267	67	16	red	red	ADJ
easat-267	67	17	cells	cell	NOUN
easat-267	67	18	infected	infect	VERB
easat-267	67	19	with	with	ADP
easat-267	67	20	plasmodium	plasmodium	NOUN
easat-267	67	21	falciparum	falciparum	NOUN
easat-267	67	22	are	be	AUX
easat-267	67	23	preferentially	preferentially	ADV
easat-267	67	24	removed	remove	VERB
easat-267	67	25	by	by	ADP
easat-267	67	26	a	a	DET
easat-267	67	27	mechanism	mechanism	NOUN
easat-267	67	28	of	of	ADP
easat-267	67	29	macrophages	macrophage	NOUN
easat-267	67	30	[	[	X
easat-267	67	31	17,19	17,19	NUM
easat-267	67	32	]	]	PUNCT
easat-267	67	33	.	.	PUNCT
easat-267	68	1	on	on	ADP
easat-267	68	2	the	the	DET
easat-267	68	3	other	other	ADJ
easat-267	68	4	hand	hand	NOUN
easat-267	68	5	,	,	PUNCT
easat-267	68	6	patients	patient	NOUN
easat-267	68	7	homozygous	homozygous	ADJ
easat-267	68	8	for	for	ADP
easat-267	68	9	the	the	DET
easat-267	68	10	sickle	sickle	NOUN
easat-267	68	11	gene	gene	NOUN
easat-267	68	12	,	,	PUNCT
easat-267	68	13	suffer	suffer	VERB
easat-267	68	14	from	from	ADP
easat-267	68	15	sickle	sickle	NOUN
easat-267	68	16	cell	cell	NOUN
easat-267	68	17	anemia	anemia	NOUN
easat-267	68	18	,	,	PUNCT
easat-267	68	19	are	be	AUX
easat-267	68	20	highly	highly	ADV
easat-267	68	21	susceptible	susceptible	ADJ
easat-267	68	22	to	to	ADP
easat-267	68	23	the	the	DET
easat-267	68	24	lethal	lethal	ADJ
easat-267	68	25	effects	effect	NOUN
easat-267	68	26	of	of	ADP
easat-267	68	27	malaria	malaria	NOUN
easat-267	69	1	[	[	X
easat-267	69	2	14	14	NUM
easat-267	69	3	]	]	PUNCT
easat-267	69	4	.	.	PUNCT
easat-267	70	1	the	the	DET
easat-267	70	2	simplest	simple	ADJ
easat-267	70	3	explanation	explanation	NOUN
easat-267	70	4	of	of	ADP
easat-267	70	5	this	this	DET
easat-267	70	6	fact	fact	NOUN
easat-267	70	7	is	be	AUX
easat-267	70	8	that	that	SCONJ
easat-267	70	9	malaria	malaria	NOUN
easat-267	70	10	makes	make	VERB
easat-267	70	11	the	the	DET
easat-267	70	12	anemia	anemia	NOUN
easat-267	70	13	of	of	ADP
easat-267	70	14	homozygous	homozygous	ADJ
easat-267	70	15	(	(	PUNCT
easat-267	70	16	hb	hb	PROPN
easat-267	70	17	ss	ss	PROPN
easat-267	70	18	)	)	PUNCT
easat-267	70	19	cells	cell	NOUN
easat-267	70	20	more	more	ADV
easat-267	70	21	severe	severe	ADJ
easat-267	70	22	;	;	PUNCT
easat-267	70	23	leading	lead	VERB
easat-267	70	24	to	to	ADP
easat-267	70	25	often	often	ADV
easat-267	70	26	hyposplenism	hyposplenism	NOUN
easat-267	70	27	,	,	PUNCT
easat-267	70	28	which	which	PRON
easat-267	70	29	reduces	reduce	VERB
easat-267	70	30	the	the	DET
easat-267	70	31	clearance	clearance	NOUN
easat-267	70	32	of	of	ADP
easat-267	70	33	parasites	parasite	NOUN
easat-267	70	34	.	.	PUNCT
easat-267	71	1	from	from	ADP
easat-267	71	2	public	public	ADJ
easat-267	71	3	health	health	NOUN
easat-267	71	4	point	point	NOUN
easat-267	71	5	of	of	ADP
easat-267	71	6	view	view	NOUN
easat-267	71	7	,	,	PUNCT
easat-267	71	8	it	it	PRON
easat-267	71	9	is	be	AUX
easat-267	71	10	important	important	ADJ
easat-267	71	11	that	that	SCONJ
easat-267	71	12	in	in	ADP
easat-267	71	13	malar	malar	ADJ
easat-267	71	14	iaendemic	iaendemic	ADJ
easat-267	71	15	countries	country	NOUN
easat-267	71	16	,	,	PUNCT
easat-267	71	17	the	the	DET
easat-267	71	18	patients	patient	NOUN
easat-267	71	19	with	with	ADP
easat-267	71	20	sickle	sickle	PROPN
easat-267	71	21	cell	cell	NOUN
easat-267	71	22	anemia	anemia	NOUN
easat-267	71	23	,	,	PUNCT
easat-267	71	24	and	and	CCONJ
easat-267	71	25	particularly	particularly	ADV
easat-267	71	26	the	the	DET
easat-267	71	27	children	child	NOUN
easat-267	71	28	,	,	PUNCT
easat-267	71	29	are	be	AUX
easat-267	71	30	being	be	AUX
easat-267	71	31	protected	protect	VERB
easat-267	71	32	from	from	ADP
easat-267	71	33	malaria	malaria	NOUN
easat-267	71	34	by	by	ADP
easat-267	71	35	appropriate	appropriate	ADJ
easat-267	71	36	prophylaxis	prophylaxi	NOUN
easat-267	71	37	[	[	X
easat-267	71	38	14,21,22	14,21,22	NUM
easat-267	71	39	]	]	X
easat-267	71	40	.	.	PUNCT
easat-267	72	1	since	since	SCONJ
easat-267	72	2	the	the	DET
easat-267	72	3	humans	human	NOUN
easat-267	72	4	,	,	PUNCT
easat-267	72	5	like	like	ADP
easat-267	72	6	most	most	ADJ
easat-267	72	7	animals	animal	NOUN
easat-267	72	8	,	,	PUNCT
easat-267	72	9	are	be	AUX
easat-267	72	10	diploid	diploid	ADJ
easat-267	72	11	,	,	PUNCT
easat-267	72	12	therefore	therefore	ADV
easat-267	72	13	,	,	PUNCT
easat-267	72	14	have	have	AUX
easat-267	72	15	more	more	ADJ
easat-267	72	16	options	option	NOUN
easat-267	72	17	in	in	ADP
easat-267	72	18	this	this	DET
easat-267	72	19	respect	respect	NOUN
easat-267	72	20	.	.	PUNCT
easat-267	73	1	sickle	sickle	NOUN
easat-267	73	2	cell	cell	PROPN
easat-267	73	3	anemia	anemia	NOUN
easat-267	73	4	is	be	AUX
easat-267	73	5	a	a	DET
easat-267	73	6	disease	disease	NOUN
easat-267	73	7	of	of	ADP
easat-267	73	8	homozygotes	homozygote	NOUN
easat-267	73	9	(	(	PUNCT
easat-267	73	10	hb	hb	X
easat-267	73	11	ss)-that	ss)-that	PROPN
easat-267	73	12	’s	’	VERB
easat-267	73	13	why	why	SCONJ
easat-267	73	14	it	it	PRON
easat-267	73	15	is	be	AUX
easat-267	73	16	called	call	VERB
easat-267	73	17	recessive	recessive	ADJ
easat-267	73	18	disease	disease	NOUN
easat-267	73	19	-	-	PUNCT
easat-267	73	20	whereas	whereas	ADV
easat-267	73	21	,	,	PUNCT
easat-267	73	22	heterozygotes	heterozygote	NOUN
easat-267	73	23	(	(	PUNCT
easat-267	73	24	hb	hb	X
easat-267	73	25	as	as	ADP
easat-267	73	26	)	)	PUNCT
easat-267	73	27	are	be	AUX
easat-267	73	28	normal	normal	ADJ
easat-267	73	29	for	for	ADP
easat-267	73	30	most	most	ADJ
easat-267	73	31	intents	intent	NOUN
easat-267	73	32	and	and	CCONJ
easat-267	73	33	purposes	purpose	NOUN
easat-267	73	34	.	.	PUNCT
easat-267	74	1	the	the	DET
easat-267	74	2	first	first	ADJ
easat-267	74	3	test	test	NOUN
easat-267	74	4	of	of	ADP
easat-267	74	5	haldane	haldane	PROPN
easat-267	74	6	’s	’s	PART
easat-267	74	7	hypothesis	hypothesis	NOUN
easat-267	74	8	was	be	AUX
easat-267	74	9	carried	carry	VERB
easat-267	74	10	out	out	ADP
easat-267	74	11	by	by	ADP
easat-267	74	12	allison	allison	PROPN
easat-267	74	13	when	when	SCONJ
easat-267	74	14	he	he	PRON
easat-267	74	15	showed	show	VERB
easat-267	74	16	not	not	PART
easat-267	74	17	only	only	ADV
easat-267	74	18	that	that	SCONJ
easat-267	74	19	the	the	DET
easat-267	74	20	s	s	NOUN
easat-267	74	21	gene	gene	NOUN
easat-267	74	22	was	be	AUX
easat-267	74	23	frequent	frequent	ADJ
easat-267	74	24	in	in	ADP
easat-267	74	25	areas	area	NOUN
easat-267	74	26	of	of	ADP
easat-267	74	27	high	high	ADJ
easat-267	74	28	malaria	malaria	NOUN
easat-267	74	29	transmission	transmission	NOUN
easat-267	74	30	,	,	PUNCT
easat-267	74	31	but	but	CCONJ
easat-267	74	32	also	also	ADV
easat-267	74	33	that	that	SCONJ
easat-267	74	34	as	as	ADP
easat-267	74	35	(	(	PUNCT
easat-267	74	36	hb	hb	PROPN
easat-267	74	37	)	)	PUNCT
easat-267	74	38	heterozygotes	heterozygote	NOUN
easat-267	74	39	seemed	seem	VERB
easat-267	74	40	to	to	PART
easat-267	74	41	have	have	VERB
easat-267	74	42	less	less	ADJ
easat-267	74	43	malaria	malaria	NOUN
easat-267	75	1	[	[	X
easat-267	75	2	4,23	4,23	NUM
easat-267	75	3	]	]	X
easat-267	75	4	.	.	PUNCT
easat-267	76	1	by	by	ADP
easat-267	76	2	the	the	DET
easat-267	76	3	laws	law	NOUN
easat-267	76	4	of	of	ADP
easat-267	76	5	population	population	NOUN
easat-267	76	6	genetics	genetic	NOUN
easat-267	76	7	it	it	PRON
easat-267	76	8	is	be	AUX
easat-267	76	9	to	to	PART
easat-267	76	10	be	be	AUX
easat-267	76	11	expected	expect	VERB
easat-267	76	12	that	that	SCONJ
easat-267	76	13	wherever	wherever	SCONJ
easat-267	76	14	the	the	DET
easat-267	76	15	sickle	sickle	NOUN
easat-267	76	16	(	(	PUNCT
easat-267	76	17	s	s	X
easat-267	76	18	)	)	PUNCT
easat-267	76	19	gene	gene	NOUN
easat-267	76	20	is	be	AUX
easat-267	76	21	common	common	ADJ
easat-267	76	22	,	,	PUNCT
easat-267	76	23	there	there	PRON
easat-267	76	24	will	will	AUX
easat-267	76	25	be	be	AUX
easat-267	76	26	many	many	ADJ
easat-267	76	27	patients	patient	NOUN
easat-267	76	28	suffering	suffer	VERB
easat-267	76	29	from	from	ADP
easat-267	76	30	sickle	sickle	NOUN
easat-267	76	31	cell	cell	NOUN
easat-267	76	32	anemia	anemia	NOUN
easat-267	76	33	,	,	PUNCT
easat-267	76	34	a	a	DET
easat-267	76	35	severe	severe	ADJ
easat-267	76	36	burden	burden	NOUN
easat-267	76	37	in	in	ADP
easat-267	76	38	the	the	DET
easat-267	76	39	population	population	NOUN
easat-267	77	1	[	[	X
easat-267	77	2	21,24	21,24	X
easat-267	77	3	]	]	PUNCT
easat-267	77	4	.	.	PUNCT
easat-267	78	1	however	however	ADV
easat-267	78	2	,	,	PUNCT
easat-267	78	3	in	in	ADP
easat-267	78	4	the	the	DET
easat-267	78	5	same	same	ADJ
easat-267	78	6	population	population	NOUN
easat-267	78	7	a	a	DET
easat-267	78	8	much	much	ADV
easat-267	78	9	larger	large	ADJ
easat-267	78	10	number	number	NOUN
easat-267	78	11	of	of	ADP
easat-267	78	12	heterozygotes	heterozygote	NOUN
easat-267	78	13	(	(	PUNCT
easat-267	78	14	hb	hb	X
easat-267	78	15	as	as	ADP
easat-267	78	16	)	)	PUNCT
easat-267	78	17	will	will	AUX
easat-267	78	18	have	have	VERB
easat-267	78	19	the	the	DET
easat-267	78	20	advantage	advantage	NOUN
easat-267	78	21	of	of	ADP
easat-267	78	22	being	be	AUX
easat-267	78	23	‘	'	PUNCT
easat-267	78	24	malaria	malaria	NOUN
easat-267	78	25	-	-	PUNCT
easat-267	78	26	resistant	resistant	ADJ
easat-267	78	27	’	'	PUNCT
easat-267	78	28	.	.	PUNCT
easat-267	79	1	the	the	DET
easat-267	79	2	disadvantage	disadvantage	NOUN
easat-267	79	3	of	of	ADP
easat-267	79	4	homozygotes	homozygote	NOUN
easat-267	79	5	(	(	PUNCT
easat-267	79	6	hb	hb	PROPN
easat-267	79	7	ss	ss	PROPN
easat-267	79	8	)	)	PUNCT
easat-267	79	9	coexisting	coexist	VERB
easat-267	79	10	with	with	ADP
easat-267	79	11	the	the	DET
easat-267	79	12	advantage	advantage	NOUN
easat-267	79	13	of	of	ADP
easat-267	79	14	heterozygotes	heterozygote	NOUN
easat-267	79	15	(	(	PUNCT
easat-267	79	16	hb	hb	X
easat-267	79	17	as)-therefore	as)-therefore	PROPN
easat-267	79	18	called	call	VERB
easat-267	79	19	a	a	DET
easat-267	79	20	balanced	balanced	ADJ
easat-267	79	21	polymorphism	polymorphism	NOUN
easat-267	79	22	.	.	PUNCT
easat-267	80	1	with	with	ADP
easat-267	80	2	the	the	DET
easat-267	80	3	s	s	PROPN
easat-267	80	4	gene	gene	NOUN
easat-267	80	5	,	,	PUNCT
easat-267	80	6	it	it	PRON
easat-267	80	7	became	become	VERB
easat-267	80	8	clear	clear	ADJ
easat-267	80	9	that	that	SCONJ
easat-267	80	10	balanced	balanced	ADJ
easat-267	80	11	polymorphism	polymorphism	NOUN
easat-267	80	12	,	,	PUNCT
easat-267	80	13	in	in	ADP
easat-267	80	14	which	which	PRON
easat-267	80	15	the	the	DET
easat-267	80	16	severe	severe	ADJ
easat-267	80	17	disease	disease	NOUN
easat-267	80	18	of	of	ADP
easat-267	80	19	homozygotes	homozygote	NOUN
easat-267	80	20	(	(	PUNCT
easat-267	80	21	hb	hb	X
easat-267	80	22	ss	ss	PROPN
easat-267	80	23	or	or	CCONJ
easat-267	80	24	sca	sca	NOUN
easat-267	80	25	)	)	PUNCT
easat-267	80	26	is	be	AUX
easat-267	80	27	balanced	balance	VERB
easat-267	80	28	by	by	ADP
easat-267	80	29	the	the	DET
easat-267	80	30	advantage	advantage	NOUN
easat-267	80	31	of	of	ADP
easat-267	80	32	hb	hb	PROPN
easat-267	80	33	as	as	ADP
easat-267	80	34	heterozygotes	heterozygote	NOUN
easat-267	80	35	,	,	PUNCT
easat-267	80	36	is	be	AUX
easat-267	80	37	a	a	DET
easat-267	80	38	reality	reality	NOUN
easat-267	80	39	also	also	ADV
easat-267	80	40	in	in	ADP
easat-267	80	41	the	the	DET
easat-267	80	42	human	human	ADJ
easat-267	80	43	species	specie	NOUN
easat-267	80	44	(	(	PUNCT
easat-267	80	45	tables	table	NOUN
easat-267	80	46	1	1	NUM
easat-267	80	47	-	-	SYM
easat-267	80	48	4	4	NUM
easat-267	80	49	)	)	PUNCT
easat-267	80	50	.	.	PUNCT
easat-267	81	1	table	table	NOUN
easat-267	81	2	1	1	NUM
easat-267	81	3	.	.	PUNCT
easat-267	82	1	distribution	distribution	NOUN
easat-267	82	2	of	of	ADP
easat-267	82	3	sickle	sickle	NOUN
easat-267	82	4	cell	cell	NOUN
easat-267	82	5	trait	trait	NOUN
easat-267	82	6	and	and	CCONJ
easat-267	82	7	g6pd	g6pd	NOUN
easat-267	82	8	deficiency	deficiency	NOUN
easat-267	82	9	in	in	ADP
easat-267	82	10	18	18	NUM
easat-267	82	11	major	major	ADJ
easat-267	82	12	scheduled	schedule	VERB
easat-267	82	13	tribes	tribe	NOUN
easat-267	82	14	of	of	ADP
easat-267	82	15	odisha	odisha	PROPN
easat-267	82	16	,	,	PUNCT
easat-267	82	17	india	india	PROPN
easat-267	82	18	.	.	PUNCT
easat-267	83	1	tribe	tribe	PROPN
easat-267	83	2	district	district	PROPN
easat-267	83	3	n	n	CCONJ
easat-267	83	4	sickle	sickle	NOUN
easat-267	83	5	cell	cell	NOUN
easat-267	83	6	trait	trait	NOUN
easat-267	83	7	g6pd	g6pd	NOUN
easat-267	83	8	deficiency	deficiency	NOUN
easat-267	83	9	male	male	ADJ
easat-267	83	10	male+female	male+female	PROPN
easat-267	83	11	n	n	CCONJ
easat-267	83	12	%	%	NOUN
easat-267	83	13	n	n	PRON
easat-267	83	14	%	%	NOUN
easat-267	83	15	n	n	PRON
easat-267	83	16	%	%	NOUN
easat-267	83	17	primitive	primitive	ADJ
easat-267	83	18	tribe	tribe	NOUN
easat-267	83	19	bondo	bondo	NOUN
easat-267	83	20	malkangiri	malkangiri	NOUN
easat-267	83	21	962	962	NUM
easat-267	83	22	7	7	NUM
easat-267	83	23	0.7	0.7	NUM
easat-267	83	24	6	6	NUM
easat-267	83	25	0.6	0.6	NUM
easat-267	83	26	paudi	paudi	NOUN
easat-267	83	27	bhuyan	bhuyan	NOUN
easat-267	83	28	sundargarh	sundargarh	VERB
easat-267	83	29	379	379	NUM
easat-267	83	30	0	0	NUM
easat-267	83	31	0	0	NUM
easat-267	83	32	30	30	NUM
easat-267	83	33	8.1	8.1	NUM
easat-267	83	34	52	52	NUM
easat-267	83	35	13.8	13.8	NUM
easat-267	83	36	didayi	didayi	NOUN
easat-267	83	37	malkangiri	malkangiri	NOUN
easat-267	83	38	1014	1014	NUM
easat-267	83	39	32	32	NUM
easat-267	83	40	3.2	3.2	NUM
easat-267	83	41	16	16	NUM
easat-267	83	42	1.6	1.6	NUM
easat-267	83	43	46	46	NUM
easat-267	83	44	edelweiss	edelweiss	PROPN
easat-267	83	45	applied	apply	VERB
easat-267	83	46	science	science	NOUN
easat-267	83	47	and	and	CCONJ
easat-267	83	48	technology	technology	NOUN
easat-267	83	49	issn	issn	PROPN
easat-267	83	50	:	:	PUNCT
easat-267	83	51	2576	2576	NUM
easat-267	83	52	-	-	SYM
easat-267	83	53	8484	8484	NUM
easat-267	83	54	vol	vol	NOUN
easat-267	83	55	.	.	PROPN
easat-267	84	1	3	3	NUM
easat-267	84	2	,	,	PUNCT
easat-267	84	3	no	no	INTJ
easat-267	84	4	.	.	NOUN
easat-267	84	5	1	1	NUM
easat-267	84	6	:	:	SYM
easat-267	84	7	44	44	NUM
easat-267	84	8	-	-	SYM
easat-267	84	9	52	52	NUM
easat-267	84	10	,	,	PUNCT
easat-267	84	11	2019	2019	NUM
easat-267	84	12	doi	doi	NOUN
easat-267	84	13	:	:	PUNCT
easat-267	84	14	10.33805/2576	10.33805/2576	NUM
easat-267	84	15	-	-	SYM
easat-267	84	16	8484.167	8484.167	NUM
easat-267	84	17	©	©	PROPN
easat-267	84	18	2019	2019	NUM
easat-267	84	19	by	by	ADP
easat-267	84	20	the	the	DET
easat-267	84	21	author	author	NOUN
easat-267	84	22	juang	juang	PROPN
easat-267	84	23	keonjhar	keonjhar	PROPN
easat-267	84	24	1065	1065	NUM
easat-267	84	25	29	29	NUM
easat-267	84	26	2.7	2.7	NUM
easat-267	84	27	46	46	NUM
easat-267	84	28	4.3	4.3	NUM
easat-267	84	29	kutia	kutia	PROPN
easat-267	84	30	kondh	kondh	PROPN
easat-267	84	31	kandhamal	kandhamal	PROPN
easat-267	84	32	65	65	NUM
easat-267	84	33	2	2	NUM
easat-267	84	34	3.1	3.1	NUM
easat-267	84	35	4	4	NUM
easat-267	84	36	7.1	7.1	NUM
easat-267	84	37	4	4	NUM
easat-267	84	38	6.1	6.1	NUM
easat-267	84	39	lodha	lodha	PROPN
easat-267	84	40	mayurbhanj	mayurbhanj	ADJ
easat-267	84	41	78	78	NUM
easat-267	84	42	0	0	NUM
easat-267	84	43	0	0	NUM
easat-267	84	44	3	3	NUM
easat-267	84	45	5.3	5.3	NUM
easat-267	84	46	4	4	NUM
easat-267	84	47	5.1	5.1	NUM
easat-267	84	48	saora	saora	NOUN
easat-267	84	49	gajapati	gajapati	VERB
easat-267	84	50	177	177	NUM
easat-267	84	51	13	13	NUM
easat-267	84	52	7.3	7.3	NUM
easat-267	84	53	14	14	NUM
easat-267	84	54	8.9	8.9	NUM
easat-267	84	55	14	14	NUM
easat-267	84	56	7.9	7.9	NUM
easat-267	84	57	lanjia	lanjia	PROPN
easat-267	84	58	saora	saora	PROPN
easat-267	84	59	gajapati	gajapati	PROPN
easat-267	84	60	74	74	NUM
easat-267	84	61	9	9	NUM
easat-267	84	62	13.2	13.2	NUM
easat-267	84	63	5	5	NUM
easat-267	84	64	7.9	7.9	NUM
easat-267	84	65	5	5	NUM
easat-267	84	66	6.8	6.8	NUM
easat-267	84	67	sabar	sabar	NOUN
easat-267	84	68	ganjam	ganjam	VERB
easat-267	84	69	102	102	NUM
easat-267	84	70	2	2	NUM
easat-267	84	71	2	2	NUM
easat-267	84	72	9	9	NUM
easat-267	84	73	9.5	9.5	NUM
easat-267	84	74	9	9	NUM
easat-267	84	75	8.8	8.8	NUM
easat-267	84	76	scheduled	schedule	VERB
easat-267	84	77	tribe	tribe	NOUN
easat-267	84	78	bathudi	bathudi	PROPN
easat-267	84	79	mayurbhanj	mayurbhanj	PROPN
easat-267	84	80	95	95	NUM
easat-267	84	81	1	1	NUM
easat-267	84	82	1	1	NUM
easat-267	84	83	4	4	NUM
easat-267	84	84	8.2	8.2	NUM
easat-267	84	85	9	9	NUM
easat-267	84	86	9.5	9.5	NUM
easat-267	84	87	bhatra	bhatra	PROPN
easat-267	84	88	nawarangpur	nawarangpur	ADV
easat-267	84	89	166	166	NUM
easat-267	84	90	25	25	NUM
easat-267	84	91	15.1	15.1	NUM
easat-267	84	92	3	3	NUM
easat-267	84	93	4.3	4.3	NUM
easat-267	84	94	11	11	NUM
easat-267	84	95	6.6	6.6	NUM
easat-267	84	96	bhumiz	bhumiz	VERB
easat-267	84	97	mayurbhanj	mayurbhanj	ADJ
easat-267	84	98	116	116	NUM
easat-267	84	99	1	1	NUM
easat-267	84	100	0.9	0.9	NUM
easat-267	84	101	9	9	NUM
easat-267	84	102	12.2	12.2	NUM
easat-267	84	103	11	11	NUM
easat-267	84	104	9.5	9.5	NUM
easat-267	84	105	bhuyan	bhuyan	NOUN
easat-267	84	106	sundargarh	sundargarh	VERB
easat-267	84	107	92	92	NUM
easat-267	84	108	0	0	NUM
easat-267	84	109	0	0	NUM
easat-267	84	110	5	5	NUM
easat-267	84	111	16.7	16.7	NUM
easat-267	84	112	7	7	NUM
easat-267	84	113	12.9	12.9	NUM
easat-267	84	114	bhuyan	bhuyan	NOUN
easat-267	84	115	sundargarh	sundargarh	NOUN
easat-267	84	116	836	836	NUM
easat-267	84	117	20	20	NUM
easat-267	84	118	2.2	2.2	NUM
easat-267	84	119	84	84	NUM
easat-267	84	120	10	10	NUM
easat-267	84	121	137	137	NUM
easat-267	84	122	16.4	16.4	NUM
easat-267	84	123	paraja	paraja	NOUN
easat-267	84	124	bhuyan	bhuyan	NOUN
easat-267	84	125	sundargarh	sundargarh	VERB
easat-267	84	126	213	213	NUM
easat-267	84	127	2	2	NUM
easat-267	84	128	0.9	0.9	NUM
easat-267	84	129	29	29	NUM
easat-267	84	130	13.6	13.6	NUM
easat-267	84	131	45	45	NUM
easat-267	84	132	21.1	21.1	NUM
easat-267	84	133	paik	paik	NOUN
easat-267	84	134	bhuyan	bhuyan	PROPN
easat-267	84	135	sundargarh	sundargarh	NOUN
easat-267	84	136	244	244	NUM
easat-267	84	137	18	18	NUM
easat-267	84	138	7.3	7.3	NUM
easat-267	84	139	25	25	NUM
easat-267	84	140	10.2	10.2	NUM
easat-267	84	141	40	40	NUM
easat-267	84	142	16.4	16.4	NUM
easat-267	84	143	gond	gond	PROPN
easat-267	84	144	kalahandi	kalahandi	VERB
easat-267	84	145	219	219	NUM
easat-267	84	146	46	46	NUM
easat-267	84	147	21	21	NUM
easat-267	84	148	12	12	NUM
easat-267	84	149	8.5	8.5	NUM
easat-267	84	150	13	13	NUM
easat-267	84	151	5.9	5.9	NUM
easat-267	84	152	kharia	kharia	NOUN
easat-267	84	153	sundargarh	sundargarh	VERB
easat-267	84	154	54	54	NUM
easat-267	84	155	4	4	NUM
easat-267	84	156	7.4	7.4	NUM
easat-267	84	157	1	1	NUM
easat-267	84	158	12.5	12.5	NUM
easat-267	84	159	5	5	NUM
easat-267	84	160	14.2	14.2	NUM
easat-267	84	161	kharia	kharia	NOUN
easat-267	84	162	sundargarh	sundargarh	VERB
easat-267	84	163	767	767	NUM
easat-267	85	1	41	41	NUM
easat-267	85	2	5.4	5.4	NUM
easat-267	85	3	91	91	NUM
easat-267	85	4	11.9	11.9	NUM
easat-267	85	5	187	187	NUM
easat-267	85	6	24.4	24.4	NUM
easat-267	85	7	dudh	dudh	NOUN
easat-267	85	8	kharia	kharia	NOUN
easat-267	85	9	sundargarh	sundargarh	VERB
easat-267	85	10	422	422	NUM
easat-267	85	11	0	0	NUM
easat-267	85	12	0	0	NUM
easat-267	85	13	36	36	NUM
easat-267	85	14	8.5	8.5	NUM
easat-267	85	15	81	81	NUM
easat-267	85	16	19.2	19.2	NUM
easat-267	85	17	dhelki	dhelki	NOUN
easat-267	85	18	kharia	kharia	PROPN
easat-267	85	19	sundargarh	sundargarh	VERB
easat-267	85	20	345	345	NUM
easat-267	85	21	41	41	NUM
easat-267	85	22	11.8	11.8	NUM
easat-267	85	23	55	55	NUM
easat-267	85	24	15.9	15.9	NUM
easat-267	85	25	106	106	NUM
easat-267	85	26	30.7	30.7	NUM
easat-267	85	27	kissan	kissan	NOUN
easat-267	85	28	sundargarh	sundargarh	VERB
easat-267	85	29	130	130	NUM
easat-267	85	30	0	0	NUM
easat-267	85	31	0	0	NUM
easat-267	85	32	3	3	NUM
easat-267	85	33	5.5	5.5	NUM
easat-267	85	34	5	5	NUM
easat-267	85	35	5.1	5.1	NUM
easat-267	85	36	kolha	kolha	NOUN
easat-267	85	37	mayurbhanj	mayurbhanj	ADJ
easat-267	85	38	102	102	NUM
easat-267	85	39	0	0	NUM
easat-267	85	40	0	0	NUM
easat-267	85	41	9	9	NUM
easat-267	85	42	10.7	10.7	NUM
easat-267	85	43	10	10	NUM
easat-267	85	44	9.8	9.8	NUM
easat-267	85	45	kondh	kondh	NOUN
easat-267	85	46	kandhamal	kandhamal	PROPN
easat-267	85	47	254	254	NUM
easat-267	85	48	8	8	NUM
easat-267	85	49	3.1	3.1	NUM
easat-267	85	50	11	11	NUM
easat-267	85	51	6.2	6.2	NUM
easat-267	85	52	17	17	NUM
easat-267	85	53	6.7	6.7	NUM
easat-267	85	54	munda	munda	PROPN
easat-267	85	55	sundargarh	sundargarh	VERB
easat-267	85	56	96	96	NUM
easat-267	85	57	3	3	NUM
easat-267	85	58	3.1	3.1	NUM
easat-267	85	59	11	11	NUM
easat-267	85	60	15.9	15.9	NUM
easat-267	85	61	14	14	NUM
easat-267	85	62	15.9	15.9	NUM
easat-267	85	63	oraon	oraon	NOUN
easat-267	85	64	sundargarh	sundargarh	VERB
easat-267	85	65	104	104	NUM
easat-267	85	66	0	0	NUM
easat-267	85	67	0	0	NUM
easat-267	85	68	5	5	NUM
easat-267	85	69	8.6	8.6	NUM
easat-267	85	70	6	6	NUM
easat-267	85	71	8.2	8.2	NUM
easat-267	85	72	paraja	paraja	NOUN
easat-267	85	73	koraput	koraput	VERB
easat-267	85	74	176	176	NUM
easat-267	85	75	23	23	NUM
easat-267	85	76	13.1	13.1	NUM
easat-267	85	77	21	21	NUM
easat-267	85	78	17.4	17.4	NUM
easat-267	85	79	28	28	NUM
easat-267	85	80	15.9	15.9	NUM
easat-267	85	81	santal	santal	NOUN
easat-267	85	82	mayurbhanj	mayurbhanj	NOUN
easat-267	85	83	100	100	NUM
easat-267	85	84	1	1	NUM
easat-267	85	85	1	1	NUM
easat-267	85	86	6	6	NUM
easat-267	85	87	7.7	7.7	NUM
easat-267	85	88	9	9	NUM
easat-267	85	89	9	9	NUM
easat-267	85	90	several	several	ADJ
easat-267	85	91	studies	study	NOUN
easat-267	85	92	have	have	AUX
easat-267	85	93	suggested	suggest	VERB
easat-267	85	94	that	that	SCONJ
easat-267	85	95	high	high	ADJ
easat-267	85	96	prevalence	prevalence	NOUN
easat-267	85	97	of	of	ADP
easat-267	85	98	sickle	sickle	NOUN
easat-267	85	99	cell	cell	NOUN
easat-267	85	100	heterozygotes	heterozygote	NOUN
easat-267	85	101	(	(	PUNCT
easat-267	85	102	hb	hb	X
easat-267	85	103	as	as	ADP
easat-267	85	104	)	)	PUNCT
easat-267	85	105	in	in	ADP
easat-267	85	106	several	several	ADJ
easat-267	85	107	populations	population	NOUN
easat-267	85	108	is	be	AUX
easat-267	85	109	a	a	DET
easat-267	85	110	protection	protection	NOUN
easat-267	85	111	mechanism	mechanism	NOUN
easat-267	85	112	against	against	ADP
easat-267	85	113	plasmodium	plasmodium	NOUN
easat-267	85	114	falciparum	falciparum	ADJ
easat-267	85	115	malaria	malaria	NOUN
easat-267	86	1	[	[	X
easat-267	86	2	1,2,8,10,23	1,2,8,10,23	NUM
easat-267	86	3	]	]	PUNCT
easat-267	86	4	.	.	PUNCT
easat-267	87	1	moreover	moreover	ADV
easat-267	87	2	,	,	PUNCT
easat-267	87	3	erythrocyte	erythrocyte	NOUN
easat-267	87	4	containing	contain	VERB
easat-267	87	5	hb	hb	X
easat-267	87	6	s	s	PART
easat-267	87	7	inhibit	inhibit	NOUN
easat-267	87	8	malaria	malaria	NOUN
easat-267	87	9	parasite	parasite	NOUN
easat-267	87	10	growth	growth	NOUN
easat-267	87	11	in	in	ADP
easat-267	87	12	vivo	vivo	NOUN
easat-267	87	13	and	and	CCONJ
easat-267	87	14	confer	confer	VERB
easat-267	87	15	/	/	SYM
easat-267	87	16	provide	provide	VERB
easat-267	87	17	protection	protection	NOUN
easat-267	87	18	against	against	ADP
easat-267	87	19	severe	severe	ADJ
easat-267	87	20	malaria	malaria	NOUN
easat-267	87	21	.	.	PUNCT
easat-267	88	1	the	the	DET
easat-267	88	2	following	follow	VERB
easat-267	88	3	points	point	NOUN
easat-267	88	4	have	have	AUX
easat-267	88	5	emerged	emerge	VERB
easat-267	88	6	from	from	ADP
easat-267	88	7	the	the	DET
easat-267	88	8	above	above	ADJ
easat-267	88	9	studies	study	NOUN
easat-267	88	10	:	:	PUNCT
easat-267	88	11	(	(	PUNCT
easat-267	88	12	i	i	NOUN
easat-267	88	13	)	)	PUNCT
easat-267	88	14	sickle	sickle	NOUN
easat-267	88	15	cell	cell	NOUN
easat-267	88	16	(	(	PUNCT
easat-267	88	17	hb	hb	X
easat-267	88	18	as	as	ADP
easat-267	88	19	)	)	PUNCT
easat-267	88	20	heterozygotes	heterozygote	NOUN
easat-267	88	21	do	do	AUX
easat-267	88	22	get	get	VERB
easat-267	88	23	malaria	malaria	NOUN
easat-267	88	24	.	.	PUNCT
easat-267	89	1	(	(	PUNCT
easat-267	89	2	ii	ii	NOUN
easat-267	89	3	)	)	PUNCT
easat-267	89	4	hb	hb	NOUN
easat-267	89	5	as	as	SCONJ
easat-267	89	6	heterozygotes	heterozygote	NOUN
easat-267	89	7	with	with	ADP
easat-267	89	8	malaria	malaria	NOUN
easat-267	89	9	tend	tend	VERB
easat-267	89	10	to	to	PART
easat-267	89	11	have	have	VERB
easat-267	89	12	lower	low	ADJ
easat-267	89	13	numbers	number	NOUN
easat-267	89	14	of	of	ADP
easat-267	89	15	parasitized	parasitize	VERB
easat-267	89	16	red	red	ADJ
easat-267	89	17	cells	cell	NOUN
easat-267	89	18	in	in	ADP
easat-267	89	19	their	their	PRON
easat-267	89	20	blood	blood	NOUN
easat-267	89	21	.	.	PUNCT
easat-267	90	1	(	(	PUNCT
easat-267	90	2	iii	iii	X
easat-267	90	3	)	)	PUNCT
easat-267	90	4	hb	hb	NOUN
easat-267	90	5	as	as	SCONJ
easat-267	90	6	heterozygotes	heterozygote	NOUN
easat-267	90	7	have	have	VERB
easat-267	90	8	a	a	DET
easat-267	90	9	decreased	decrease	VERB
easat-267	90	10	incidence	incidence	NOUN
easat-267	90	11	of	of	ADP
easat-267	90	12	the	the	DET
easat-267	90	13	two	two	NUM
easat-267	90	14	forms	form	NOUN
easat-267	90	15	of	of	ADP
easat-267	90	16	severe	severe	ADJ
easat-267	90	17	malaria	malaria	NOUN
easat-267	90	18	recognized	recognize	VERB
easat-267	90	19	as	as	ADP
easat-267	90	20	immediately	immediately	ADV
easat-267	90	21	life	life	NOUN
easat-267	90	22	-	-	PUNCT
easat-267	90	23	threatening	threaten	VERB
easat-267	90	24	:	:	PUNCT
easat-267	90	25	namely	namely	ADV
easat-267	90	26	,	,	PUNCT
easat-267	90	27	cerebral	cerebral	ADJ
easat-267	90	28	malaria	malaria	NOUN
easat-267	90	29	and	and	CCONJ
easat-267	90	30	malaria	malaria	NOUN
easat-267	90	31	with	with	ADP
easat-267	90	32	severe	severe	ADJ
easat-267	90	33	anemia	anemia	NOUN
easat-267	90	34	.	.	PUNCT
easat-267	91	1	(	(	PUNCT
easat-267	91	2	iv	iv	X
easat-267	91	3	)	)	PUNCT
easat-267	91	4	hb	hb	NOUN
easat-267	91	5	as	as	SCONJ
easat-267	91	6	heterozygotes	heterozygote	NOUN
easat-267	91	7	very	very	ADV
easat-267	91	8	rarely	rarely	ADV
easat-267	91	9	die	die	VERB
easat-267	91	10	of	of	ADP
easat-267	91	11	malaria	malaria	NOUN
easat-267	91	12	,	,	PUNCT
easat-267	91	13	even	even	ADV
easat-267	91	14	in	in	ADP
easat-267	91	15	the	the	DET
easat-267	91	16	rare	rare	ADJ
easat-267	91	17	cases	case	NOUN
easat-267	91	18	when	when	SCONJ
easat-267	91	19	they	they	PRON
easat-267	91	20	do	do	AUX
easat-267	91	21	develop	develop	VERB
easat-267	91	22	cerebral	cerebral	ADJ
easat-267	91	23	malaria	malaria	NOUN
easat-267	92	1	[	[	X
easat-267	92	2	25	25	NUM
easat-267	92	3	]	]	PUNCT
easat-267	92	4	.	.	PUNCT
easat-267	93	1	it	it	PRON
easat-267	93	2	is	be	AUX
easat-267	93	3	justified	justify	VERB
easat-267	93	4	that	that	SCONJ
easat-267	93	5	point	point	NOUN
easat-267	93	6	4	4	NUM
easat-267	93	7	(	(	PUNCT
easat-267	93	8	iv	iv	X
easat-267	93	9	)	)	PUNCT
easat-267	93	10	is	be	AUX
easat-267	93	11	a	a	DET
easat-267	93	12	consequence	consequence	NOUN
easat-267	93	13	of	of	ADP
easat-267	93	14	point	point	NOUN
easat-267	93	15	3	3	NUM
easat-267	93	16	(	(	PUNCT
easat-267	93	17	iii	iii	NOUN
easat-267	93	18	)	)	PUNCT
easat-267	93	19	,	,	PUNCT
easat-267	93	20	and	and	CCONJ
easat-267	93	21	point	point	VERB
easat-267	93	22	3	3	NUM
easat-267	93	23	(	(	PUNCT
easat-267	93	24	iii	iii	NOUN
easat-267	93	25	)	)	PUNCT
easat-267	93	26	is	be	AUX
easat-267	93	27	at	at	ADP
easat-267	93	28	least	least	ADJ
easat-267	93	29	to	to	ADP
easat-267	93	30	some	some	DET
easat-267	93	31	extent	extent	NOUN
easat-267	93	32	the	the	DET
easat-267	93	33	result	result	NOUN
easat-267	93	34	of	of	ADP
easat-267	93	35	point	point	NOUN
easat-267	93	36	2	2	NUM
easat-267	93	37	(	(	PUNCT
easat-267	93	38	ii	ii	NOUN
easat-267	93	39	)	)	PUNCT
easat-267	93	40	.	.	PUNCT
easat-267	94	1	from	from	ADP
easat-267	94	2	clinical	clinical	ADJ
easat-267	94	3	epidemiology	epidemiology	NOUN
easat-267	94	4	point	point	NOUN
easat-267	94	5	of	of	ADP
easat-267	94	6	view	view	NOUN
easat-267	94	7	,	,	PUNCT
easat-267	94	8	the	the	DET
easat-267	94	9	above	above	ADJ
easat-267	94	10	logistics	logistic	NOUN
easat-267	94	11	are	be	AUX
easat-267	94	12	consistent	consistent	ADJ
easat-267	94	13	with	with	ADP
easat-267	94	14	increased	increase	VERB
easat-267	94	15	fitness	fitness	NOUN
easat-267	94	16	of	of	ADP
easat-267	94	17	as	as	ADP
easat-267	94	18	heterozygotes	heterozygote	NOUN
easat-267	94	19	in	in	ADP
easat-267	94	20	malaria	malaria	ADJ
easat-267	94	21	endemic	endemic	ADJ
easat-267	94	22	environment	environment	NOUN
easat-267	94	23	(	(	PUNCT
easat-267	94	24	there	there	PRON
easat-267	94	25	would	would	AUX
easat-267	94	26	be	be	AUX
easat-267	94	27	no	no	DET
easat-267	94	28	advantage	advantage	NOUN
easat-267	94	29	without	without	ADP
easat-267	94	30	malaria	malaria	NOUN
easat-267	94	31	)	)	PUNCT
easat-267	94	32	and	and	CCONJ
easat-267	94	33	hb	hb	X
easat-267	94	34	s	s	X
easat-267	94	35	is	be	AUX
easat-267	94	36	not	not	PART
easat-267	94	37	an	an	DET
easat-267	94	38	absolute	absolute	ADJ
easat-267	94	39	impediment	impediment	NOUN
easat-267	94	40	to	to	ADP
easat-267	94	41	the	the	DET
easat-267	94	42	malaria	malaria	NOUN
easat-267	94	43	parasite	parasite	NOUN
easat-267	94	44	[	[	X
easat-267	94	45	17	17	NUM
easat-267	94	46	]	]	PUNCT
easat-267	94	47	.	.	PUNCT
easat-267	95	1	therefore	therefore	ADV
easat-267	95	2	,	,	PUNCT
easat-267	95	3	the	the	DET
easat-267	95	4	mechanism	mechanism	NOUN
easat-267	95	5	for	for	ADP
easat-267	95	6	the	the	DET
easat-267	95	7	increased	increase	VERB
easat-267	95	8	fitness	fitness	NOUN
easat-267	95	9	of	of	ADP
easat-267	95	10	hb	hb	PROPN
easat-267	95	11	as	as	ADP
easat-267	95	12	heterozygotes	heterozygote	NOUN
easat-267	95	13	is	be	AUX
easat-267	95	14	not	not	PART
easat-267	95	15	failure	failure	NOUN
easat-267	95	16	of	of	ADP
easat-267	95	17	invading	invade	VERB
easat-267	95	18	red	red	ADJ
easat-267	95	19	cells	cell	NOUN
easat-267	95	20	,	,	PUNCT
easat-267	95	21	but	but	CCONJ
easat-267	95	22	once	once	ADV
easat-267	95	23	the	the	DET
easat-267	95	24	parasite	parasite	NOUN
easat-267	95	25	has	have	AUX
easat-267	95	26	triggered	trigger	VERB
easat-267	95	27	sickling	sickle	VERB
easat-267	95	28	-	-	PUNCT
easat-267	95	29	enhanced	enhance	VERB
easat-267	95	30	-	-	PUNCT
easat-267	95	31	removal	removal	NOUN
easat-267	95	32	of	of	ADP
easat-267	95	33	parasitized	parasitized	ADJ
easat-267	95	34	sickle	sickle	NOUN
easat-267	95	35	cells	cell	NOUN
easat-267	95	36	would	would	AUX
easat-267	95	37	take	take	VERB
easat-267	95	38	place	place	NOUN
easat-267	95	39	by	by	ADP
easat-267	95	40	macrophages	macrophage	NOUN
easat-267	95	41	[	[	X
easat-267	95	42	26	26	NUM
easat-267	95	43	]	]	PUNCT
easat-267	95	44	.	.	PUNCT
easat-267	96	1	thus	thus	ADV
easat-267	96	2	,	,	PUNCT
easat-267	96	3	the	the	DET
easat-267	96	4	invasion	invasion	NOUN
easat-267	96	5	of	of	ADP
easat-267	96	6	plasmodium	plasmodium	NOUN
easat-267	96	7	falciparum	falciparum	NOUN
easat-267	96	8	on	on	ADP
easat-267	96	9	hb	hb	PROPN
easat-267	96	10	as	as	SCONJ
easat-267	96	11	heterozygote	heterozygote	NOUN
easat-267	96	12	cells	cell	NOUN
easat-267	96	13	amounts	amount	VERB
easat-267	96	14	to	to	ADP
easat-267	96	15	suicidal	suicidal	ADJ
easat-267	96	16	infection	infection	NOUN
easat-267	96	17	and	and	CCONJ
easat-267	96	18	the	the	DET
easat-267	96	19	parasitized	parasitized	ADJ
easat-267	96	20	sickle	sickle	NOUN
easat-267	96	21	cells	cell	NOUN
easat-267	96	22	phagocytose	phagocytose	VERB
easat-267	96	23	rapidly	rapidly	ADV
easat-267	96	24	.	.	PUNCT
easat-267	97	1	the	the	DET
easat-267	97	2	clinically	clinically	ADV
easat-267	97	3	relevant	relevant	ADJ
easat-267	97	4	consequence	consequence	NOUN
easat-267	97	5	of	of	ADP
easat-267	97	6	this	this	DET
easat-267	97	7	process	process	NOUN
easat-267	97	8	is	be	AUX
easat-267	97	9	to	to	PART
easat-267	97	10	keep	keep	VERB
easat-267	97	11	parasitemia	parasitemia	NOUN
easat-267	97	12	relatively	relatively	ADV
easat-267	97	13	lower	low	ADJ
easat-267	97	14	in	in	ADP
easat-267	97	15	hb	hb	PROPN
easat-267	97	16	as	as	ADP
easat-267	97	17	heterozygotes	heterozygote	NOUN
easat-267	97	18	,	,	PUNCT
easat-267	97	19	and	and	CCONJ
easat-267	97	20	probably	probably	ADV
easat-267	97	21	the	the	DET
easat-267	97	22	same	same	ADJ
easat-267	97	23	mechanism	mechanism	NOUN
easat-267	97	24	applies	apply	VERB
easat-267	97	25	also	also	ADV
easat-267	97	26	to	to	ADP
easat-267	97	27	parasitized	parasitize	VERB
easat-267	97	28	g6pd	g6pd	NOUN
easat-267	97	29	deficient	deficient	ADJ
easat-267	97	30	red	red	ADJ
easat-267	97	31	cells	cell	NOUN
easat-267	97	32	[	[	X
easat-267	97	33	27	27	NUM
easat-267	97	34	-	-	SYM
easat-267	97	35	32	32	NUM
easat-267	97	36	]	]	PUNCT
easat-267	97	37	.	.	PUNCT
easat-267	98	1	these	these	DET
easat-267	98	2	mechanisms	mechanism	NOUN
easat-267	98	3	include	include	VERB
easat-267	98	4	accelerated	accelerate	VERB
easat-267	98	5	sickling	sickle	VERB
easat-267	98	6	of	of	ADP
easat-267	98	7	parasite	parasite	NOUN
easat-267	98	8	infected	infect	VERB
easat-267	98	9	(	(	PUNCT
easat-267	98	10	hb	hb	X
easat-267	98	11	as	as	ADP
easat-267	98	12	)	)	PUNCT
easat-267	98	13	erythrocytes	erythrocytes	ADJ
easat-267	98	14	,	,	PUNCT
easat-267	98	15	low	low	ADJ
easat-267	98	16	growth	growth	NOUN
easat-267	98	17	rates	rate	NOUN
easat-267	98	18	,	,	PUNCT
easat-267	98	19	and	and	CCONJ
easat-267	98	20	parasite	parasite	NOUN
easat-267	98	21	invasion	invasion	NOUN
easat-267	98	22	in	in	ADP
easat-267	98	23	(	(	PUNCT
easat-267	98	24	hb	hb	X
easat-267	98	25	as	as	ADP
easat-267	98	26	)	)	PUNCT
easat-267	98	27	erythrocytes	erythrocyte	NOUN
easat-267	98	28	(	(	PUNCT
easat-267	98	29	in	in	ADP
easat-267	98	30	low	low	ADJ
easat-267	98	31	oxygen	oxygen	NOUN
easat-267	98	32	conditions	condition	NOUN
easat-267	98	33	)	)	PUNCT
easat-267	98	34	,	,	PUNCT
easat-267	98	35	and	and	CCONJ
easat-267	98	36	increased	increase	VERB
easat-267	98	37	phagocytosis	phagocytosis	NOUN
easat-267	98	38	of	of	ADP
easat-267	98	39	infected	infected	ADJ
easat-267	98	40	(	(	PUNCT
easat-267	98	41	hb	hb	X
easat-267	98	42	as	as	ADP
easat-267	98	43	)	)	PUNCT
easat-267	98	44	erythrocytes	erythrocyte	NOUN
easat-267	98	45	.	.	PUNCT
easat-267	99	1	however	however	ADV
easat-267	99	2	,	,	PUNCT
easat-267	99	3	the	the	DET
easat-267	99	4	experimental	experimental	ADJ
easat-267	99	5	data	datum	NOUN
easat-267	99	6	support	support	NOUN
easat-267	99	7	only	only	ADV
easat-267	99	8	:	:	PUNCT
easat-267	99	9	1	1	X
easat-267	99	10	)	)	PUNCT
easat-267	99	11	intra	intra	ADJ
easat-267	99	12	-	-	ADJ
easat-267	99	13	erythrocyte	erythrocyte	ADJ
easat-267	99	14	parasite	parasite	NOUN
easat-267	99	15	growth	growth	NOUN
easat-267	99	16	is	be	AUX
easat-267	99	17	greatly	greatly	ADV
easat-267	99	18	inhibited	inhibit	VERB
easat-267	99	19	by	by	ADP
easat-267	99	20	sickle	sickle	NOUN
easat-267	99	21	cell	cell	NOUN
easat-267	99	22	polymerization	polymerization	NOUN
easat-267	99	23	when	when	SCONJ
easat-267	99	24	oxygen	oxygen	NOUN
easat-267	99	25	levels	level	NOUN
easat-267	99	26	drop	drop	VERB
easat-267	99	27	below	below	ADP
easat-267	99	28	5	5	NUM
easat-267	99	29	%	%	NOUN
easat-267	99	30	and	and	CCONJ
easat-267	99	31	2	2	NUM
easat-267	99	32	)	)	PUNCT
easat-267	99	33	higher	high	ADJ
easat-267	99	34	parasite	parasite	NOUN
easat-267	99	35	infected	infect	VERB
easat-267	99	36	sickle	sickle	NOUN
easat-267	99	37	erythrocytes	erythrocyte	NOUN
easat-267	99	38	phagocytosis	phagocytosis	NOUN
easat-267	99	39	by	by	ADP
easat-267	99	40	host	host	NOUN
easat-267	99	41	immune	immune	ADJ
easat-267	99	42	cells	cell	NOUN
easat-267	99	43	has	have	AUX
easat-267	99	44	been	be	AUX
easat-267	99	45	observed	observe	VERB
easat-267	99	46	when	when	SCONJ
easat-267	99	47	compared	compare	VERB
easat-267	99	48	to	to	ADP
easat-267	99	49	infected	infect	VERB
easat-267	99	50	normal	normal	ADJ
easat-267	99	51	erythrocytes	erythrocyte	NOUN
easat-267	99	52	[	[	X
easat-267	99	53	27,33	27,33	NUM
easat-267	99	54	]	]	PUNCT
easat-267	99	55	.	.	PUNCT
easat-267	100	1	it	it	PRON
easat-267	100	2	has	have	AUX
easat-267	100	3	also	also	ADV
easat-267	100	4	been	be	AUX
easat-267	100	5	shown	show	VERB
easat-267	100	6	that	that	SCONJ
easat-267	100	7	hb	hb	PROPN
easat-267	100	8	s	s	PART
easat-267	100	9	erythrocytes	erythrocyte	NOUN
easat-267	100	10	infected	infect	VERB
easat-267	100	11	by	by	ADP
easat-267	100	12	plasmodium	plasmodium	NOUN
easat-267	100	13	falciparum	falciparum	NOUN
easat-267	100	14	lower	low	ADJ
easat-267	100	15	the	the	DET
easat-267	100	16	surface	surface	NOUN
easat-267	100	17	expression	expression	NOUN
easat-267	100	18	of	of	ADP
easat-267	100	19	pfemp-1	pfemp-1	PROPN
easat-267	100	20	,	,	PUNCT
easat-267	100	21	which	which	PRON
easat-267	100	22	results	result	VERB
easat-267	100	23	in	in	ADP
easat-267	100	24	a	a	DET
easat-267	100	25	reduction	reduction	NOUN
easat-267	100	26	of	of	ADP
easat-267	100	27	cytoadherence	cytoadherence	NOUN
easat-267	100	28	and	and	CCONJ
easat-267	100	29	thus	thus	ADV
easat-267	100	30	,	,	PUNCT
easat-267	100	31	providing	provide	VERB
easat-267	100	32	protection	protection	NOUN
easat-267	100	33	against	against	ADP
easat-267	100	34	severe	severe	ADJ
easat-267	100	35	malaria	malaria	NOUN
easat-267	101	1	[	[	X
easat-267	101	2	34	34	NUM
easat-267	101	3	]	]	PUNCT
easat-267	101	4	.	.	PUNCT
easat-267	102	1	clinically	clinically	ADV
easat-267	102	2	,	,	PUNCT
easat-267	102	3	malaria	malaria	NOUN
easat-267	102	4	makes	make	VERB
easat-267	102	5	the	the	DET
easat-267	102	6	anemia	anemia	NOUN
easat-267	102	7	of	of	ADP
easat-267	102	8	homozygous	homozygous	ADJ
easat-267	102	9	sickle	sickle	NOUN
easat-267	102	10	cell	cell	NOUN
easat-267	102	11	disease	disease	NOUN
easat-267	102	12	cases	case	VERB
easat-267	102	13	worse	bad	ADJ
easat-267	102	14	to	to	ADP
easat-267	102	15	the	the	DET
easat-267	102	16	point	point	NOUN
easat-267	102	17	of	of	ADP
easat-267	102	18	becoming	become	VERB
easat-267	102	19	lifethreatening	lifethreatene	VERB
easat-267	102	20	;	;	PUNCT
easat-267	102	21	and	and	CCONJ
easat-267	102	22	like	like	ADP
easat-267	102	23	any	any	DET
easat-267	102	24	other	other	ADJ
easat-267	102	25	acute	acute	ADJ
easat-267	102	26	infection	infection	NOUN
easat-267	102	27	,	,	PUNCT
easat-267	102	28	malaria	malaria	NOUN
easat-267	102	29	can	can	AUX
easat-267	102	30	trigger	trigger	VERB
easat-267	102	31	sickle	sickle	NOUN
easat-267	102	32	cell	cell	NOUN
easat-267	102	33	anemia	anemia	NOUN
easat-267	102	34	in	in	ADP
easat-267	102	35	patients	patient	NOUN
easat-267	102	36	,	,	PUNCT
easat-267	102	37	leading	lead	VERB
easat-267	102	38	to	to	ADP
easat-267	102	39	a	a	DET
easat-267	102	40	pain	pain	NOUN
easat-267	102	41	crisis	crisis	NOUN
easat-267	102	42	or	or	CCONJ
easat-267	102	43	a	a	DET
easat-267	102	44	sequestration	sequestration	NOUN
easat-267	102	45	crisis	crisis	NOUN
easat-267	102	46	(	(	PUNCT
easat-267	102	47	tables	table	NOUN
easat-267	102	48	2	2	NUM
easat-267	102	49	-	-	SYM
easat-267	102	50	3	3	NUM
easat-267	102	51	)	)	PUNCT
easat-267	102	52	.	.	PUNCT
easat-267	103	1	normally	normally	ADV
easat-267	103	2	the	the	DET
easat-267	103	3	spleen	spleen	NOUN
easat-267	103	4	plays	play	VERB
easat-267	103	5	an	an	DET
easat-267	103	6	important	important	ADJ
easat-267	103	7	role	role	NOUN
easat-267	103	8	in	in	ADP
easat-267	103	9	filtering	filter	VERB
easat-267	103	10	and	and	CCONJ
easat-267	103	11	removing	remove	VERB
easat-267	103	12	parasitized	parasitize	VERB
easat-267	103	13	red	red	ADJ
easat-267	103	14	cells	cell	NOUN
easat-267	103	15	.	.	PUNCT
easat-267	104	1	but	but	CCONJ
easat-267	104	2	patients	patient	NOUN
easat-267	104	3	with	with	ADP
easat-267	104	4	sca	sca	PROPN
easat-267	104	5	regularly	regularly	ADV
easat-267	104	6	have	have	VERB
easat-267	104	7	an	an	DET
easat-267	104	8	impaired	impaired	ADJ
easat-267	104	9	splenic	splenic	ADJ
easat-267	104	10	function	function	NOUN
easat-267	104	11	;	;	PUNCT
easat-267	104	12	often	often	ADV
easat-267	104	13	to	to	ADP
easat-267	104	14	the	the	DET
easat-267	104	15	extent	extent	NOUN
easat-267	104	16	of	of	ADP
easat-267	104	17	functional	functional	ADJ
easat-267	104	18	asplenia	asplenia	NOUN
easat-267	104	19	,	,	PUNCT
easat-267	104	20	and	and	CCONJ
easat-267	104	21	sometimes	sometimes	ADV
easat-267	104	22	the	the	DET
easat-267	104	23	functional	functional	ADJ
easat-267	104	24	asplenia	asplenia	NOUN
easat-267	104	25	evolves	evolve	VERB
easat-267	104	26	to	to	ADP
easat-267	104	27	anatomical	anatomical	ADJ
easat-267	104	28	atrophy	atrophy	NOUN
easat-267	104	29	of	of	ADP
easat-267	104	30	the	the	DET
easat-267	104	31	spleen	spleen	NOUN
easat-267	104	32	from	from	ADP
easat-267	104	33	multiple	multiple	ADJ
easat-267	104	34	infarcts	infarct	NOUN
easat-267	104	35	,	,	PUNCT
easat-267	104	36	so	so	ADV
easat-267	104	37	-	-	PUNCT
easat-267	104	38	called	call	VERB
easat-267	104	39	auto	auto	NOUN
easat-267	104	40	-	-	PUNCT
easat-267	104	41	splenectomy	splenectomy	NOUN
easat-267	104	42	and	and	CCONJ
easat-267	104	43	the	the	DET
easat-267	104	44	patients	patient	NOUN
easat-267	104	45	ought	ought	AUX
easat-267	104	46	to	to	PART
easat-267	104	47	be	be	AUX
easat-267	104	48	protected	protect	VERB
easat-267	104	49	by	by	ADP
easat-267	104	50	life	life	NOUN
easat-267	104	51	-	-	PUNCT
easat-267	104	52	long	long	ADJ
easat-267	104	53	anti	anti	ADJ
easat-267	104	54	-	-	ADJ
easat-267	104	55	malarial	malarial	ADJ
easat-267	104	56	prophylaxis	prophylaxis	NOUN
easat-267	105	1	[	[	X
easat-267	105	2	35,36	35,36	NUM
easat-267	105	3	]	]	PUNCT
easat-267	105	4	.	.	PUNCT
easat-267	106	1	distinct	distinct	ADJ
easat-267	106	2	mechanisms	mechanism	NOUN
easat-267	106	3	conferring	confer	VERB
easat-267	106	4	protection	protection	NOUN
easat-267	106	5	against	against	ADP
easat-267	106	6	severe	severe	ADJ
easat-267	106	7	and	and	CCONJ
easat-267	106	8	complicated	complicated	ADJ
easat-267	106	9	malaria	malaria	NOUN
easat-267	106	10	have	have	AUX
easat-267	106	11	been	be	AUX
easat-267	106	12	proposed	propose	VERB
easat-267	106	13	for	for	ADP
easat-267	106	14	different	different	ADJ
easat-267	106	15	hemoglobinopathies	hemoglobinopathy	NOUN
easat-267	106	16	such	such	ADJ
easat-267	106	17	as	as	ADP
easat-267	106	18	sickle	sickle	NOUN
easat-267	106	19	cell	cell	NOUN
easat-267	106	20	trait	trait	NOUN
easat-267	106	21	(	(	PUNCT
easat-267	106	22	hb	hb	X
easat-267	106	23	as	as	ADP
easat-267	106	24	)	)	PUNCT
easat-267	106	25	,	,	PUNCT
easat-267	106	26	sickle	sickle	NOUN
easat-267	106	27	cell	cell	NOUN
easat-267	106	28	anemia	anemia	NOUN
easat-267	106	29	(	(	PUNCT
easat-267	106	30	hb	hb	PROPN
easat-267	106	31	ss	ss	PROPN
easat-267	106	32	)	)	PUNCT
easat-267	106	33	,	,	PUNCT
easat-267	106	34	αand	αand	ADV
easat-267	106	35	β	β	X
easat-267	106	36	-	-	PUNCT
easat-267	106	37	thalassemias	thalassemias	NOUN
easat-267	106	38	by	by	ADP
easat-267	106	39	several	several	ADJ
easat-267	106	40	investigators	investigator	NOUN
easat-267	106	41	[	[	X
easat-267	106	42	2,16,17	2,16,17	NUM
easat-267	106	43	]	]	PUNCT
easat-267	106	44	.	.	PUNCT
easat-267	107	1	high	high	ADJ
easat-267	107	2	fetal	fetal	ADJ
easat-267	107	3	and	and	CCONJ
easat-267	107	4	childhood	childhood	NOUN
easat-267	107	5	mortality	mortality	NOUN
easat-267	107	6	have	have	AUX
easat-267	107	7	also	also	ADV
easat-267	107	8	recently	recently	ADV
easat-267	107	9	been	be	AUX
easat-267	107	10	described	describe	VERB
easat-267	107	11	[	[	PUNCT
easat-267	107	12	37,38	37,38	NOUN
easat-267	107	13	]	]	PUNCT
easat-267	107	14	.	.	PUNCT
easat-267	108	1	among	among	ADP
easat-267	108	2	the	the	DET
easat-267	108	3	most	most	ADV
easat-267	108	4	relevant	relevant	ADJ
easat-267	108	5	mechanisms	mechanism	NOUN
easat-267	108	6	,	,	PUNCT
easat-267	108	7	reduced	reduce	VERB
easat-267	108	8	erythrocyte	erythrocyte	NOUN
easat-267	108	9	invasion	invasion	NOUN
easat-267	108	10	by	by	ADP
easat-267	108	11	the	the	DET
easat-267	108	12	parasite	parasite	NOUN
easat-267	108	13	,	,	PUNCT
easat-267	108	14	decreased	decrease	VERB
easat-267	108	15	intra	intra	ADJ
easat-267	108	16	-	-	ADJ
easat-267	108	17	erythrocyte	erythrocyte	ADJ
easat-267	108	18	parasite	parasite	NOUN
easat-267	108	19	growth	growth	NOUN
easat-267	108	20	enhanced	enhance	VERB
easat-267	108	21	phagocytosis	phagocytosis	NOUN
easat-267	108	22	of	of	ADP
easat-267	108	23	parasite	parasite	NOUN
easat-267	108	24	-	-	PUNCT
easat-267	108	25	infected	infect	VERB
easat-267	108	26	erythrocytes	erythrocyte	NOUN
easat-267	108	27	and	and	CCONJ
easat-267	108	28	increased	increase	VERB
easat-267	108	29	immune	immune	ADJ
easat-267	108	30	response	response	NOUN
easat-267	108	31	against	against	ADP
easat-267	108	32	parasite	parasite	NOUN
easat-267	108	33	infected	infect	VERB
easat-267	108	34	erythrocytes	erythrocyte	NOUN
easat-267	108	35	have	have	AUX
easat-267	108	36	been	be	AUX
easat-267	108	37	described	describe	VERB
easat-267	108	38	[	[	PRON
easat-267	108	39	27,31,39,40	27,31,39,40	NUM
easat-267	108	40	]	]	X
easat-267	108	41	.	.	PUNCT
easat-267	109	1	thus	thus	ADV
easat-267	109	2	,	,	PUNCT
easat-267	109	3	malaria	malaria	NOUN
easat-267	109	4	and	and	CCONJ
easat-267	109	5	sickle	sickle	PROPN
easat-267	109	6	cell	cell	NOUN
easat-267	109	7	anemia	anemia	NOUN
easat-267	109	8	are	be	AUX
easat-267	109	9	still	still	ADV
easat-267	109	10	major	major	ADJ
easat-267	109	11	challenges	challenge	NOUN
easat-267	109	12	,	,	PUNCT
easat-267	109	13	being	be	AUX
easat-267	109	14	the	the	DET
easat-267	109	15	major	major	ADJ
easat-267	109	16	public	public	ADJ
easat-267	109	17	health	health	NOUN
easat-267	109	18	problems	problem	NOUN
easat-267	109	19	.	.	PUNCT
easat-267	110	1	patients	patient	NOUN
easat-267	110	2	with	with	ADP
easat-267	110	3	sickle	sickle	PROPN
easat-267	110	4	cell	cell	NOUN
easat-267	110	5	anemia	anemia	NOUN
easat-267	110	6	carry	carry	VERB
easat-267	110	7	the	the	DET
easat-267	110	8	genetic	genetic	ADJ
easat-267	110	9	burden	burden	NOUN
easat-267	110	10	that	that	PRON
easat-267	110	11	has	have	AUX
easat-267	110	12	helped	help	VERB
easat-267	110	13	human	human	ADJ
easat-267	110	14	populations	population	NOUN
easat-267	110	15	to	to	PART
easat-267	110	16	survive	survive	VERB
easat-267	110	17	in	in	ADP
easat-267	110	18	malaria	malaria	NOUN
easat-267	110	19	-	-	PUNCT
easat-267	110	20	endemic	endemic	ADJ
easat-267	110	21	regions	region	NOUN
easat-267	110	22	of	of	ADP
easat-267	110	23	the	the	DET
easat-267	110	24	world	world	NOUN
easat-267	110	25	.	.	PUNCT
easat-267	111	1	the	the	DET
easat-267	111	2	protective	protective	ADJ
easat-267	111	3	effect	effect	NOUN
easat-267	111	4	of	of	ADP
easat-267	111	5	the	the	DET
easat-267	111	6	hb	hb	PROPN
easat-267	111	7	s	s	PROPN
easat-267	111	8	gene	gene	NOUN
easat-267	111	9	against	against	ADP
easat-267	111	10	malaria	malaria	NOUN
easat-267	111	11	is	be	AUX
easat-267	111	12	one	one	NUM
easat-267	111	13	of	of	ADP
easat-267	111	14	the	the	DET
easat-267	111	15	best	good	ADJ
easat-267	111	16	documented	document	VERB
easat-267	111	17	examples	example	NOUN
easat-267	111	18	in	in	ADP
easat-267	111	19	the	the	DET
easat-267	111	20	human	human	ADJ
easat-267	111	21	species	specie	NOUN
easat-267	111	22	of	of	ADP
easat-267	111	23	balanced	balanced	ADJ
easat-267	111	24	polymorphism	polymorphism	NOUN
easat-267	111	25	,	,	PUNCT
easat-267	111	26	in	in	ADP
easat-267	111	27	which	which	PRON
easat-267	111	28	the	the	DET
easat-267	111	29	severe	severe	ADJ
easat-267	111	30	disease	disease	NOUN
easat-267	111	31	of	of	ADP
easat-267	111	32	homozygotes	homozygote	NOUN
easat-267	111	33	(	(	PUNCT
easat-267	111	34	hb	hb	X
easat-267	111	35	ss	ss	PROPN
easat-267	111	36	or	or	CCONJ
easat-267	111	37	sca	sca	NOUN
easat-267	111	38	)	)	PUNCT
easat-267	111	39	is	be	AUX
easat-267	111	40	balanced	balance	VERB
easat-267	111	41	by	by	ADP
easat-267	111	42	the	the	DET
easat-267	111	43	advantage	advantage	NOUN
easat-267	111	44	of	of	ADP
easat-267	111	45	hb	hb	PROPN
easat-267	111	46	as	as	ADP
easat-267	111	47	heterozygotes	heterozygote	NOUN
easat-267	111	48	(	(	PUNCT
easat-267	111	49	tables	table	NOUN
easat-267	111	50	1	1	NUM
easat-267	111	51	-	-	SYM
easat-267	111	52	4	4	NUM
easat-267	111	53	)	)	PUNCT
easat-267	111	54	.	.	PUNCT
easat-267	112	1	47	47	NUM
easat-267	112	2	edelweiss	edelweiss	PROPN
easat-267	112	3	applied	apply	VERB
easat-267	112	4	science	science	NOUN
easat-267	112	5	and	and	CCONJ
easat-267	112	6	technology	technology	NOUN
easat-267	112	7	issn	issn	PROPN
easat-267	112	8	:	:	PUNCT
easat-267	112	9	2576	2576	NUM
easat-267	112	10	-	-	SYM
easat-267	112	11	8484	8484	NUM
easat-267	112	12	vol	vol	NOUN
easat-267	112	13	.	.	PROPN
easat-267	113	1	3	3	NUM
easat-267	113	2	,	,	PUNCT
easat-267	113	3	no	no	INTJ
easat-267	113	4	.	.	NOUN
easat-267	113	5	1	1	NUM
easat-267	113	6	:	:	SYM
easat-267	113	7	44	44	NUM
easat-267	113	8	-	-	SYM
easat-267	113	9	52	52	NUM
easat-267	113	10	,	,	PUNCT
easat-267	113	11	2019	2019	NUM
easat-267	113	12	doi	doi	NOUN
easat-267	113	13	:	:	PUNCT
easat-267	113	14	10.33805/2576	10.33805/2576	NUM
easat-267	113	15	-	-	SYM
easat-267	113	16	8484.167	8484.167	NUM
easat-267	113	17	©	©	PROPN
easat-267	113	18	2019	2019	NUM
easat-267	113	19	by	by	ADP
easat-267	113	20	the	the	DET
easat-267	113	21	author	author	NOUN
easat-267	113	22	table	table	NOUN
easat-267	113	23	2	2	NUM
easat-267	113	24	.	.	PUNCT
easat-267	114	1	distribution	distribution	NOUN
easat-267	114	2	of	of	ADP
easat-267	114	3	sickle	sickle	NOUN
easat-267	114	4	cell	cell	NOUN
easat-267	114	5	trait	trait	NOUN
easat-267	114	6	and	and	CCONJ
easat-267	114	7	g6pd	g6pd	NOUN
easat-267	114	8	deficiency	deficiency	NOUN
easat-267	114	9	in	in	ADP
easat-267	114	10	scheduled	schedule	VERB
easat-267	114	11	tribe	tribe	NOUN
easat-267	114	12	communities	community	NOUN
easat-267	114	13	of	of	ADP
easat-267	114	14	chhattisgarh	chhattisgarh	PROPN
easat-267	114	15	,	,	PUNCT
easat-267	114	16	india	india	PROPN
easat-267	114	17	.	.	PUNCT
easat-267	115	1	tribe	tribe	PROPN
easat-267	115	2	district	district	PROPN
easat-267	115	3	n	n	CCONJ
easat-267	115	4	sickle	sickle	NOUN
easat-267	115	5	cell	cell	NOUN
easat-267	115	6	trait	trait	NOUN
easat-267	115	7	g6pd	g6pd	NOUN
easat-267	115	8	deficiency	deficiency	NOUN
easat-267	115	9	male	male	ADJ
easat-267	115	10	male+female	male+female	PROPN
easat-267	115	11	n	n	CCONJ
easat-267	115	12	%	%	NOUN
easat-267	115	13	n	n	PRON
easat-267	115	14	%	%	NOUN
easat-267	115	15	n	n	PRON
easat-267	115	16	%	%	NOUN
easat-267	115	17	primitive	primitive	ADJ
easat-267	115	18	tribe	tribe	NOUN
easat-267	115	19	birhor	birhor	NOUN
easat-267	115	20	raigarh	raigarh	VERB
easat-267	115	21	270	270	NUM
easat-267	115	22	0	0	NUM
easat-267	115	23	0	0	NUM
easat-267	115	24	0	0	NUM
easat-267	115	25	0	0	NUM
easat-267	115	26	hill	hill	NOUN
easat-267	115	27	korwa	korwa	PROPN
easat-267	115	28	jashpur	jashpur	VERB
easat-267	115	29	744	744	NUM
easat-267	115	30	13	13	NUM
easat-267	115	31	1.7	1.7	NUM
easat-267	115	32	32	32	NUM
easat-267	115	33	6.4	6.4	NUM
easat-267	115	34	hill	hill	NOUN
easat-267	115	35	korwa	korwa	PROPN
easat-267	115	36	surguja	surguja	PROPN
easat-267	115	37	402	402	NUM
easat-267	115	38	0	0	NUM
easat-267	115	39	0	0	NUM
easat-267	115	40	6	6	NUM
easat-267	115	41	1.6	1.6	NUM
easat-267	115	42	kamar	kamar	PROPN
easat-267	115	43	raipur	raipur	PROPN
easat-267	115	44	320	320	NUM
easat-267	115	45	3	3	NUM
easat-267	115	46	0.9	0.9	NUM
easat-267	115	47	5	5	NUM
easat-267	115	48	1.6	1.6	NUM
easat-267	115	49	kawar	kawar	NOUN
easat-267	115	50	ambikapur	ambikapur	VERB
easat-267	115	51	114	114	NUM
easat-267	115	52	1	1	NUM
easat-267	115	53	0.9	0.9	NUM
easat-267	115	54	22	22	NUM
easat-267	115	55	16	16	NUM
easat-267	115	56	kawar	kawar	NOUN
easat-267	115	57	raipur	raipur	NOUN
easat-267	115	58	72	72	NUM
easat-267	115	59	4	4	NUM
easat-267	115	60	5.5	5.5	NUM
easat-267	115	61	25	25	NUM
easat-267	115	62	21.5	21.5	NUM
easat-267	115	63	hill	hill	NOUN
easat-267	115	64	maria	maria	PROPN
easat-267	115	65	bastar	bastar	NOUN
easat-267	115	66	93	93	NUM
easat-267	115	67	21	21	NUM
easat-267	115	68	22.5	22.5	NUM
easat-267	115	69	3	3	NUM
easat-267	115	70	3.6	3.6	NUM
easat-267	115	71	maria	maria	NOUN
easat-267	115	72	bastar	bastar	NOUN
easat-267	115	73	94	94	NUM
easat-267	115	74	19	19	NUM
easat-267	115	75	20.2	20.2	NUM
easat-267	115	76	0	0	NUM
easat-267	115	77	0	0	NUM
easat-267	115	78	maria	maria	NOUN
easat-267	115	79	bastar	bastar	NOUN
easat-267	115	80	101	101	NUM
easat-267	115	81	14	14	NUM
easat-267	115	82	13.9	13.9	NUM
easat-267	115	83	14	14	NUM
easat-267	115	84	14	14	NUM
easat-267	115	85	muria	muria	NOUN
easat-267	115	86	bastar	bastar	NOUN
easat-267	115	87	101	101	NUM
easat-267	115	88	15	15	NUM
easat-267	115	89	14.9	14.9	NUM
easat-267	115	90	3	3	NUM
easat-267	115	91	2.7	2.7	NUM
easat-267	115	92	scheduled	schedule	VERB
easat-267	115	93	tribe	tribe	NOUN
easat-267	115	94	bhatra	bhatra	PROPN
easat-267	115	95	bastar	bastar	PROPN
easat-267	115	96	102	102	NUM
easat-267	115	97	10	10	NUM
easat-267	115	98	9.8	9.8	NUM
easat-267	115	99	3	3	NUM
easat-267	115	100	2.9	2.9	NUM
easat-267	115	101	bhatra	bhatra	PROPN
easat-267	115	102	bastar	bastar	NOUN
easat-267	115	103	99	99	NUM
easat-267	115	104	13	13	NUM
easat-267	115	105	13.1	13.1	NUM
easat-267	115	106	0	0	NUM
easat-267	115	107	0	0	NUM
easat-267	115	108	dhurwa	dhurwa	NOUN
easat-267	115	109	bastar	bastar	NOUN
easat-267	115	110	81	81	NUM
easat-267	115	111	5	5	NUM
easat-267	115	112	6.2	6.2	NUM
easat-267	115	113	0	0	NUM
easat-267	115	114	0	0	NUM
easat-267	115	115	gond	gond	PROPN
easat-267	115	116	ambikapur	ambikapur	VERB
easat-267	115	117	127	127	NUM
easat-267	115	118	26	26	NUM
easat-267	115	119	20.5	20.5	NUM
easat-267	115	120	22	22	NUM
easat-267	115	121	13	13	NUM
easat-267	115	122	gond	gond	PROPN
easat-267	115	123	raipur	raipur	PROPN
easat-267	115	124	157	157	NUM
easat-267	115	125	25	25	NUM
easat-267	115	126	15.9	15.9	NUM
easat-267	115	127	46	46	NUM
easat-267	115	128	16.2	16.2	NUM
easat-267	115	129	halba	halba	PROPN
easat-267	115	130	raipur	raipur	PROPN
easat-267	115	131	122	122	NUM
easat-267	115	132	17	17	NUM
easat-267	115	133	13.9	13.9	NUM
easat-267	115	134	8	8	NUM
easat-267	115	135	7.4	7.4	NUM
easat-267	115	136	halba	halba	PRON
easat-267	115	137	bastar	bastar	NOUN
easat-267	115	138	99	99	NUM
easat-267	115	139	12	12	NUM
easat-267	115	140	12.1	12.1	NUM
easat-267	115	141	4	4	NUM
easat-267	115	142	3.6	3.6	NUM
easat-267	115	143	halba	halba	NOUN
easat-267	115	144	rajnandgaon	rajnandgaon	VERB
easat-267	115	145	or	or	CCONJ
easat-267	115	146	durg	durg	NOUN
easat-267	115	147	365	365	NUM
easat-267	115	148	54	54	NUM
easat-267	115	149	15.6	15.6	NUM
easat-267	115	150	4	4	NUM
easat-267	115	151	1	1	NUM
easat-267	115	152	halba	halba	PROPN
easat-267	115	153	bastar	bastar	NOUN
easat-267	115	154	95	95	NUM
easat-267	115	155	18	18	NUM
easat-267	115	156	19	19	NUM
easat-267	115	157	2	2	NUM
easat-267	115	158	1.8	1.8	NUM
easat-267	115	159	kodaku	kodaku	NOUN
easat-267	115	160	surguja	surguja	NOUN
easat-267	115	161	400	400	NUM
easat-267	115	162	12	12	NUM
easat-267	115	163	3	3	NUM
easat-267	115	164	7	7	NUM
easat-267	115	165	1.8	1.8	NUM
easat-267	115	166	oraon	oraon	NOUN
easat-267	115	167	ambikapur	ambikapur	VERB
easat-267	115	168	422	422	NUM
easat-267	115	169	9	9	NUM
easat-267	115	170	2.1	2.1	NUM
easat-267	115	171	55	55	NUM
easat-267	115	172	13.4	13.4	NUM
easat-267	115	173	oraon	oraon	ADJ
easat-267	115	174	raigarh	raigarh	NOUN
easat-267	115	175	,	,	PUNCT
easat-267	115	176	surguja	surguja	NOUN
easat-267	115	177	215	215	NUM
easat-267	115	178	0	0	NUM
easat-267	115	179	0	0	NUM
easat-267	115	180	0	0	NUM
easat-267	115	181	0	0	NUM
easat-267	115	182	pando	pando	PROPN
easat-267	115	183	*	*	PUNCT
easat-267	115	184	surguja	surguja	NOUN
easat-267	115	185	458	458	NUM
easat-267	115	186	5	5	NUM
easat-267	115	187	1.1	1.1	NUM
easat-267	115	188	5	5	NUM
easat-267	115	189	1.1	1.1	NUM
easat-267	115	190	1.5	1.5	NUM
easat-267	115	191	.	.	PUNCT
easat-267	116	1	hemoglobin	hemoglobin	NOUN
easat-267	116	2	c	c	PROPN
easat-267	116	3	disease	disease	NOUN
easat-267	116	4	the	the	DET
easat-267	116	5	hemoglobin	hemoglobin	NOUN
easat-267	116	6	variants	variant	NOUN
easat-267	116	7	/	/	SYM
easat-267	116	8	mutants	mutant	NOUN
easat-267	116	9	,	,	PUNCT
easat-267	116	10	namely	namely	ADV
easat-267	116	11	,	,	PUNCT
easat-267	116	12	hb	hb	PROPN
easat-267	116	13	c	c	PROPN
easat-267	116	14	and	and	CCONJ
easat-267	116	15	hb	hb	PROPN
easat-267	116	16	s	s	PROPN
easat-267	116	17	,	,	PUNCT
easat-267	116	18	are	be	AUX
easat-267	116	19	known	know	VERB
easat-267	116	20	to	to	PART
easat-267	116	21	protect	protect	VERB
easat-267	116	22	carriers	carrier	NOUN
easat-267	116	23	from	from	ADP
easat-267	116	24	severe	severe	ADJ
easat-267	116	25	falciparum	falciparum	ADJ
easat-267	116	26	malaria	malaria	NOUN
easat-267	116	27	.	.	PUNCT
easat-267	117	1	there	there	PRON
easat-267	117	2	is	be	VERB
easat-267	117	3	a	a	DET
easat-267	117	4	malaria	malaria	NOUN
easat-267	117	5	protection	protection	NOUN
easat-267	117	6	-	-	PUNCT
easat-267	117	7	inducing	induce	VERB
easat-267	117	8	mechanism	mechanism	NOUN
easat-267	117	9	,	,	PUNCT
easat-267	117	10	that	that	SCONJ
easat-267	117	11	intra	intra	ADJ
easat-267	117	12	-	-	ADJ
easat-267	117	13	erythrocyte	erythrocyte	ADJ
easat-267	117	14	parasite	parasite	NOUN
easat-267	117	15	growth	growth	NOUN
easat-267	117	16	becomes	becomes	AUX
easat-267	117	17	reduced	reduce	VERB
easat-267	117	18	in	in	ADP
easat-267	117	19	individuals	individual	NOUN
easat-267	117	20	having	have	VERB
easat-267	117	21	hb	hb	PRON
easat-267	117	22	c	c	PROPN
easat-267	117	23	erythrocytes	erythrocyte	NOUN
easat-267	117	24	in	in	ADP
easat-267	117	25	both	both	CCONJ
easat-267	117	26	mild	mild	ADJ
easat-267	117	27	and	and	CCONJ
easat-267	117	28	severe	severe	ADJ
easat-267	117	29	malarial	malarial	ADJ
easat-267	117	30	infection	infection	NOUN
easat-267	117	31	.	.	PUNCT
easat-267	118	1	individuals	individual	NOUN
easat-267	118	2	homozygous	homozygous	ADJ
easat-267	118	3	for	for	ADP
easat-267	118	4	hb	hb	PROPN
easat-267	118	5	cc	cc	PROPN
easat-267	118	6	display	display	VERB
easat-267	118	7	a	a	DET
easat-267	118	8	reduced	reduced	ADJ
easat-267	118	9	risk	risk	NOUN
easat-267	118	10	of	of	ADP
easat-267	118	11	having	have	VERB
easat-267	118	12	severe	severe	ADJ
easat-267	118	13	or	or	CCONJ
easat-267	118	14	non	non	ADJ
easat-267	118	15	-	-	ADJ
easat-267	118	16	severe	severe	ADJ
easat-267	118	17	infection	infection	NOUN
easat-267	118	18	by	by	ADP
easat-267	118	19	plasmodium	plasmodium	NOUN
easat-267	118	20	falciparum	falciparum	ADJ
easat-267	118	21	malaria	malaria	NOUN
easat-267	119	1	[	[	X
easat-267	119	2	17,41	17,41	NUM
easat-267	119	3	]	]	SYM
easat-267	119	4	.	.	PUNCT
easat-267	120	1	1.6	1.6	NUM
easat-267	120	2	.	.	PUNCT
easat-267	121	1	hemoglobin	hemoglobin	NOUN
easat-267	121	2	e	e	PROPN
easat-267	121	3	disease	disease	NOUN
easat-267	121	4	heterozygous	heterozygous	ADJ
easat-267	121	5	form	form	NOUN
easat-267	121	6	of	of	ADP
easat-267	121	7	hemoglobin	hemoglobin	NOUN
easat-267	121	8	e	e	NOUN
easat-267	121	9	confers	confer	VERB
easat-267	121	10	protection	protection	NOUN
easat-267	121	11	against	against	ADP
easat-267	121	12	severe	severe	ADJ
easat-267	121	13	malarial	malarial	ADJ
easat-267	121	14	episodes	episode	NOUN
easat-267	121	15	because	because	SCONJ
easat-267	121	16	there	there	PRON
easat-267	121	17	is	be	VERB
easat-267	121	18	reduced	reduce	VERB
easat-267	121	19	erythrocyte	erythrocyte	NOUN
easat-267	121	20	invasion	invasion	NOUN
easat-267	121	21	by	by	ADP
easat-267	121	22	merozoites	merozoite	NOUN
easat-267	121	23	,	,	PUNCT
easat-267	121	24	lower	low	ADJ
easat-267	121	25	intra	intra	ADJ
easat-267	121	26	-	-	ADJ
easat-267	121	27	erythrocyte	erythrocyte	ADJ
easat-267	121	28	parasite	parasite	NOUN
easat-267	121	29	growth	growth	NOUN
easat-267	121	30	,	,	PUNCT
easat-267	121	31	and	and	CCONJ
easat-267	121	32	enhanced	enhance	VERB
easat-267	121	33	phagocytosis	phagocytosis	NOUN
easat-267	121	34	of	of	ADP
easat-267	121	35	infected	infected	ADJ
easat-267	121	36	erythrocytes	erythrocyte	NOUN
easat-267	121	37	[	[	X
easat-267	121	38	42	42	NUM
easat-267	121	39	-	-	SYM
easat-267	121	40	44	44	NUM
easat-267	121	41	]	]	PUNCT
easat-267	121	42	.	.	PUNCT
easat-267	122	1	1.7	1.7	NUM
easat-267	122	2	.	.	PUNCT
easat-267	123	1	cytoskeletal	cytoskeletal	ADJ
easat-267	123	2	abnormalities	abnormality	NOUN
easat-267	123	3	hereditary	hereditary	ADJ
easat-267	123	4	spherocytosis	spherocytosis	NOUN
easat-267	123	5	(	(	PUNCT
easat-267	123	6	also	also	ADV
easat-267	123	7	known	know	VERB
easat-267	123	8	as	as	ADP
easat-267	123	9	minkowski	minkowski	ADJ
easat-267	123	10	–	–	PUNCT
easat-267	123	11	chauffard	chauffard	ADJ
easat-267	123	12	syndrome	syndrome	NOUN
easat-267	123	13	)	)	PUNCT
easat-267	123	14	is	be	AUX
easat-267	123	15	an	an	DET
easat-267	123	16	abnormality	abnormality	NOUN
easat-267	123	17	of	of	ADP
easat-267	123	18	erythrocytes	erythrocyte	NOUN
easat-267	123	19	.	.	PUNCT
easat-267	124	1	the	the	DET
easat-267	124	2	disorder	disorder	NOUN
easat-267	124	3	is	be	AUX
easat-267	124	4	caused	cause	VERB
easat-267	124	5	by	by	ADP
easat-267	124	6	mutations	mutation	NOUN
easat-267	124	7	in	in	ADP
easat-267	124	8	genes	gene	NOUN
easat-267	124	9	relating	relate	VERB
easat-267	124	10	to	to	ADP
easat-267	124	11	membrane	membrane	ADJ
easat-267	124	12	proteins	protein	NOUN
easat-267	124	13	that	that	PRON
easat-267	124	14	allow	allow	VERB
easat-267	124	15	for	for	SCONJ
easat-267	124	16	the	the	DET
easat-267	124	17	erythrocytes	erythrocyte	NOUN
easat-267	124	18	to	to	PART
easat-267	124	19	change	change	VERB
easat-267	124	20	shape	shape	NOUN
easat-267	124	21	.	.	PUNCT
easat-267	125	1	both	both	PRON
easat-267	125	2	hereditary	hereditary	ADJ
easat-267	125	3	ovalocytosis	ovalocytosis	NOUN
easat-267	125	4	/	/	SYM
easat-267	125	5	ellyptocytosis	ellyptocytosis	NOUN
easat-267	125	6	(	(	PUNCT
easat-267	125	7	band	band	NOUN
easat-267	125	8	3	3	NUM
easat-267	125	9	variant	variant	NOUN
easat-267	125	10	)	)	PUNCT
easat-267	125	11	and	and	CCONJ
easat-267	125	12	hereditary	hereditary	ADJ
easat-267	125	13	spherocytosis	spherocytosis	NOUN
easat-267	125	14	variants	variant	NOUN
easat-267	125	15	reduce	reduce	VERB
easat-267	125	16	the	the	DET
easat-267	125	17	plasmodium	plasmodium	NOUN
easat-267	125	18	falciparum	falciparum	ADJ
easat-267	125	19	growth	growth	NOUN
easat-267	125	20	in	in	ADP
easat-267	125	21	vitro	vitro	X
easat-267	126	1	[	[	X
easat-267	126	2	45,46	45,46	NOUN
easat-267	126	3	]	]	PUNCT
easat-267	126	4	.	.	PUNCT
easat-267	127	1	ovalocytosis	ovalocytosis	NOUN
easat-267	127	2	is	be	AUX
easat-267	127	3	an	an	DET
easat-267	127	4	uncommon	uncommon	ADJ
easat-267	127	5	variant	variant	NOUN
easat-267	127	6	of	of	ADP
easat-267	127	7	hereditary	hereditary	ADJ
easat-267	127	8	ellyptocytosis	ellyptocytosis	NOUN
easat-267	127	9	belonging	belong	VERB
easat-267	127	10	to	to	ADP
easat-267	127	11	the	the	DET
easat-267	127	12	erythrocyte	erythrocyte	NOUN
easat-267	127	13	membrane	membrane	NOUN
easat-267	127	14	inherited	inherit	VERB
easat-267	127	15	disorder	disorder	NOUN
easat-267	127	16	.	.	PUNCT
easat-267	128	1	only	only	ADV
easat-267	128	2	the	the	DET
easat-267	128	3	heterozygotic	heterozygotic	ADJ
easat-267	128	4	form	form	NOUN
easat-267	128	5	,	,	PUNCT
easat-267	128	6	which	which	PRON
easat-267	128	7	is	be	AUX
easat-267	128	8	asymptomatic	asymptomatic	ADJ
easat-267	128	9	and	and	CCONJ
easat-267	128	10	endemic	endemic	ADJ
easat-267	128	11	in	in	ADP
easat-267	128	12	southeast	southeast	PROPN
easat-267	128	13	asia	asia	PROPN
easat-267	128	14	,	,	PUNCT
easat-267	128	15	derives	derive	VERB
easat-267	128	16	its	its	PRON
easat-267	128	17	name	name	NOUN
easat-267	128	18	as	as	ADP
easat-267	128	19	southeast	southeast	ADJ
easat-267	128	20	asian	asian	ADJ
easat-267	128	21	ovalocytosis	ovalocytosis	NOUN
easat-267	128	22	[	[	X
easat-267	128	23	41	41	NUM
easat-267	128	24	]	]	PUNCT
easat-267	128	25	.	.	PUNCT
easat-267	129	1	it	it	PRON
easat-267	129	2	gives	give	VERB
easat-267	129	3	protection	protection	NOUN
easat-267	129	4	against	against	ADP
easat-267	129	5	cerebral	cerebral	ADJ
easat-267	129	6	malaria	malaria	NOUN
easat-267	129	7	.	.	PUNCT
easat-267	130	1	1.8	1.8	NUM
easat-267	130	2	.	.	PUNCT
easat-267	131	1	glucose-6	glucose-6	NOUN
easat-267	131	2	-	-	PUNCT
easat-267	131	3	phosphate	phosphate	NOUN
easat-267	131	4	dehydrogenase	dehydrogenase	NOUN
easat-267	131	5	enzyme	enzyme	NOUN
easat-267	131	6	deficiency	deficiency	NOUN
easat-267	131	7	the	the	DET
easat-267	131	8	enzyme	enzyme	NOUN
easat-267	131	9	g6pd	g6pd	NOUN
easat-267	131	10	deficiency	deficiency	NOUN
easat-267	131	11	is	be	AUX
easat-267	131	12	a	a	DET
easat-267	131	13	genetic	genetic	ADJ
easat-267	131	14	disorder	disorder	NOUN
easat-267	131	15	that	that	PRON
easat-267	131	16	occurs	occur	VERB
easat-267	131	17	almost	almost	ADV
easat-267	131	18	exclusively	exclusively	ADV
easat-267	131	19	in	in	ADP
easat-267	131	20	males	male	NOUN
easat-267	131	21	.	.	PUNCT
easat-267	132	1	this	this	DET
easat-267	132	2	condition	condition	NOUN
easat-267	132	3	mainly	mainly	ADV
easat-267	132	4	affects	affect	VERB
easat-267	132	5	red	red	ADJ
easat-267	132	6	blood	blood	NOUN
easat-267	132	7	cells	cell	NOUN
easat-267	132	8	,	,	PUNCT
easat-267	132	9	which	which	PRON
easat-267	132	10	carry	carry	VERB
easat-267	132	11	oxygen	oxygen	NOUN
easat-267	132	12	from	from	ADP
easat-267	132	13	lungs	lung	NOUN
easat-267	132	14	to	to	ADP
easat-267	132	15	various	various	ADJ
easat-267	132	16	tissues	tissue	NOUN
easat-267	132	17	throughout	throughout	ADP
easat-267	132	18	the	the	DET
easat-267	132	19	body	body	NOUN
easat-267	132	20	,	,	PUNCT
easat-267	132	21	resulting	result	VERB
easat-267	132	22	in	in	ADP
easat-267	132	23	reduced	reduce	VERB
easat-267	132	24	oxygen	oxygen	NOUN
easat-267	132	25	flow	flow	NOUN
easat-267	132	26	to	to	ADP
easat-267	132	27	the	the	DET
easat-267	132	28	different	different	ADJ
easat-267	132	29	organs	organ	NOUN
easat-267	132	30	.	.	PUNCT
easat-267	133	1	this	this	PRON
easat-267	133	2	can	can	AUX
easat-267	133	3	cause	cause	VERB
easat-267	133	4	fatigue	fatigue	NOUN
easat-267	133	5	,	,	PUNCT
easat-267	133	6	yellowing	yellow	VERB
easat-267	133	7	of	of	ADP
easat-267	133	8	the	the	DET
easat-267	133	9	skin	skin	NOUN
easat-267	133	10	and	and	CCONJ
easat-267	133	11	eyes	eye	NOUN
easat-267	133	12	,	,	PUNCT
easat-267	133	13	and	and	CCONJ
easat-267	133	14	shortness	shortness	NOUN
easat-267	133	15	of	of	ADP
easat-267	133	16	breath	breath	NOUN
easat-267	133	17	.	.	PUNCT
easat-267	134	1	additional	additional	ADJ
easat-267	134	2	symptoms	symptom	NOUN
easat-267	134	3	of	of	ADP
easat-267	134	4	g6pd	g6pd	NOUN
easat-267	134	5	deficiency	deficiency	NOUN
easat-267	134	6	include	include	VERB
easat-267	134	7	:	:	PUNCT
easat-267	134	8	•	•	NUM
easat-267	134	9	rapid	rapid	ADJ
easat-267	134	10	heart	heart	NOUN
easat-267	134	11	rate	rate	NOUN
easat-267	134	12	•	•	NOUN
easat-267	134	13	shortness	shortness	NOUN
easat-267	134	14	of	of	ADP
easat-267	134	15	breath	breath	NOUN
easat-267	134	16	•	•	NOUN
easat-267	134	17	urine	urine	NOUN
easat-267	134	18	is	be	AUX
easat-267	134	19	dark	dark	ADJ
easat-267	134	20	or	or	CCONJ
easat-267	134	21	yellow	yellow	ADJ
easat-267	134	22	-	-	PUNCT
easat-267	134	23	orange	orange	NOUN
easat-267	134	24	•	•	ADJ
easat-267	134	25	fever	fever	NOUN
easat-267	134	26	•	•	NOUN
easat-267	134	27	fatigue	fatigue	NOUN
easat-267	134	28	•	•	NOUN
easat-267	134	29	dizziness	dizziness	NOUN
easat-267	134	30	•	•	NOUN
easat-267	134	31	paleness	paleness	NOUN
easat-267	134	32	•	•	NUM
easat-267	134	33	jaundice	jaundice	NOUN
easat-267	134	34	,	,	PUNCT
easat-267	134	35	or	or	CCONJ
easat-267	134	36	yellowing	yellowing	NOUN
easat-267	134	37	of	of	ADP
easat-267	134	38	the	the	DET
easat-267	134	39	skin	skin	NOUN
easat-267	134	40	and	and	CCONJ
easat-267	134	41	whites	white	NOUN
easat-267	134	42	of	of	ADP
easat-267	134	43	the	the	DET
easat-267	134	44	eyes	eye	NOUN
easat-267	134	45	the	the	DET
easat-267	134	46	g6pd	g6pd	NOUN
easat-267	134	47	enzyme	enzyme	NOUN
easat-267	134	48	deficiency	deficiency	NOUN
easat-267	134	49	results	result	NOUN
easat-267	134	50	from	from	ADP
easat-267	134	51	mutations	mutation	NOUN
easat-267	134	52	in	in	ADP
easat-267	134	53	the	the	DET
easat-267	134	54	g6pd	g6pd	NOUN
easat-267	134	55	gene	gene	NOUN
easat-267	134	56	.	.	PUNCT
easat-267	135	1	the	the	DET
easat-267	135	2	mutation	mutation	NOUN
easat-267	135	3	reduces	reduce	VERB
easat-267	135	4	the	the	DET
easat-267	135	5	amount	amount	NOUN
easat-267	135	6	of	of	ADP
easat-267	135	7	g6pd	g6pd	NOUN
easat-267	135	8	enzyme	enzyme	NOUN
easat-267	135	9	or	or	CCONJ
easat-267	135	10	alters	alter	VERB
easat-267	135	11	its	its	PRON
easat-267	135	12	structure	structure	NOUN
easat-267	135	13	,	,	PUNCT
easat-267	135	14	so	so	SCONJ
easat-267	135	15	that	that	SCONJ
easat-267	135	16	enzyme	enzyme	NOUN
easat-267	135	17	can	can	AUX
easat-267	135	18	no	no	ADV
easat-267	135	19	longer	long	ADV
easat-267	135	20	play	play	VERB
easat-267	135	21	its	its	PRON
easat-267	135	22	protective	protective	ADJ
easat-267	135	23	role	role	NOUN
easat-267	135	24	.	.	PUNCT
easat-267	136	1	as	as	ADP
easat-267	136	2	a	a	DET
easat-267	136	3	result	result	NOUN
easat-267	136	4	,	,	PUNCT
easat-267	136	5	reactive	reactive	ADJ
easat-267	136	6	oxygen	oxygen	NOUN
easat-267	136	7	species	specie	NOUN
easat-267	136	8	can	can	AUX
easat-267	136	9	accumulate	accumulate	VERB
easat-267	136	10	and	and	CCONJ
easat-267	136	11	damage	damage	VERB
easat-267	136	12	red	red	ADJ
easat-267	136	13	blood	blood	NOUN
easat-267	136	14	cells	cell	NOUN
easat-267	136	15	.	.	PUNCT
easat-267	137	1	factors	factor	NOUN
easat-267	137	2	such	such	ADJ
easat-267	137	3	as	as	ADP
easat-267	137	4	infections	infection	NOUN
easat-267	137	5	,	,	PUNCT
easat-267	137	6	certain	certain	ADJ
easat-267	137	7	drugs	drug	NOUN
easat-267	137	8	,	,	PUNCT
easat-267	137	9	or	or	CCONJ
easat-267	137	10	ingesting	ingest	VERB
easat-267	137	11	fava	fava	NOUN
easat-267	137	12	beans	bean	NOUN
easat-267	137	13	can	can	AUX
easat-267	137	14	increase	increase	VERB
easat-267	137	15	the	the	DET
easat-267	137	16	levels	level	NOUN
easat-267	137	17	of	of	ADP
easat-267	137	18	reactive	reactive	ADJ
easat-267	137	19	oxygen	oxygen	NOUN
easat-267	137	20	species	specie	NOUN
easat-267	137	21	,	,	PUNCT
easat-267	137	22	causing	cause	VERB
easat-267	137	23	destruction	destruction	NOUN
easat-267	137	24	of	of	ADP
easat-267	137	25	erythrocytes	erythrocyte	NOUN
easat-267	137	26	faster	fast	ADV
easat-267	137	27	than	than	SCONJ
easat-267	137	28	the	the	DET
easat-267	137	29	body	body	NOUN
easat-267	137	30	can	can	AUX
easat-267	137	31	replace	replace	VERB
easat-267	137	32	them	they	PRON
easat-267	137	33	.	.	PUNCT
easat-267	138	1	a	a	DET
easat-267	138	2	reduction	reduction	NOUN
easat-267	138	3	in	in	ADP
easat-267	138	4	number	number	NOUN
easat-267	138	5	of	of	ADP
easat-267	138	6	red	red	ADJ
easat-267	138	7	blood	blood	NOUN
easat-267	138	8	cells	cell	NOUN
easat-267	138	9	causes	cause	VERB
easat-267	138	10	the	the	DET
easat-267	138	11	signs	sign	NOUN
easat-267	138	12	and	and	CCONJ
easat-267	138	13	symptoms	symptom	NOUN
easat-267	138	14	of	of	ADP
easat-267	138	15	hemolytic	hemolytic	ADJ
easat-267	138	16	anemia	anemia	NOUN
easat-267	138	17	.	.	PUNCT
easat-267	139	1	g6pd	g6pd	NOUN
easat-267	139	2	enzyme	enzyme	NOUN
easat-267	139	3	involves	involve	VERB
easat-267	139	4	in	in	ADP
easat-267	139	5	the	the	DET
easat-267	139	6	normal	normal	ADJ
easat-267	139	7	processing	processing	NOUN
easat-267	139	8	of	of	ADP
easat-267	139	9	carbohydrates	carbohydrate	NOUN
easat-267	139	10	metabolism	metabolism	NOUN
easat-267	139	11	.	.	PUNCT
easat-267	140	1	it	it	PRON
easat-267	140	2	also	also	ADV
easat-267	140	3	protects	protect	VERB
easat-267	140	4	red	red	ADJ
easat-267	140	5	blood	blood	NOUN
easat-267	140	6	cells	cell	NOUN
easat-267	140	7	from	from	ADP
easat-267	140	8	the	the	DET
easat-267	140	9	effects	effect	NOUN
easat-267	140	10	of	of	ADP
easat-267	140	11	potentially	potentially	ADV
easat-267	140	12	harmful	harmful	ADJ
easat-267	140	13	molecules	molecule	NOUN
easat-267	140	14	called	call	VERB
easat-267	140	15	reactive	reactive	ADJ
easat-267	140	16	oxygen	oxygen	NOUN
easat-267	140	17	species	specie	NOUN
easat-267	140	18	by	by	ADP
easat-267	140	19	products	product	NOUN
easat-267	140	20	of	of	ADP
easat-267	140	21	normal	normal	ADJ
easat-267	140	22	cellular	cellular	ADJ
easat-267	140	23	functions	function	NOUN
easat-267	140	24	.	.	PUNCT
easat-267	141	1	48	48	NUM
easat-267	141	2	edelweiss	edelweiss	PROPN
easat-267	141	3	applied	apply	VERB
easat-267	141	4	science	science	NOUN
easat-267	141	5	and	and	CCONJ
easat-267	141	6	technology	technology	NOUN
easat-267	141	7	issn	issn	PROPN
easat-267	141	8	:	:	PUNCT
easat-267	141	9	2576	2576	NUM
easat-267	141	10	-	-	SYM
easat-267	141	11	8484	8484	NUM
easat-267	141	12	vol	vol	NOUN
easat-267	141	13	.	.	PROPN
easat-267	142	1	3	3	NUM
easat-267	142	2	,	,	PUNCT
easat-267	142	3	no	no	INTJ
easat-267	142	4	.	.	NOUN
easat-267	142	5	1	1	NUM
easat-267	142	6	:	:	SYM
easat-267	142	7	44	44	NUM
easat-267	142	8	-	-	SYM
easat-267	142	9	52	52	NUM
easat-267	142	10	,	,	PUNCT
easat-267	142	11	2019	2019	NUM
easat-267	142	12	doi	doi	NOUN
easat-267	142	13	:	:	PUNCT
easat-267	142	14	10.33805/2576	10.33805/2576	NUM
easat-267	142	15	-	-	SYM
easat-267	142	16	8484.167	8484.167	NUM
easat-267	142	17	©	©	PROPN
easat-267	142	18	2019	2019	NUM
easat-267	142	19	by	by	ADP
easat-267	142	20	the	the	DET
easat-267	142	21	author	author	NOUN
easat-267	142	22	table	table	NOUN
easat-267	142	23	3	3	NUM
easat-267	142	24	.	.	PUNCT
easat-267	143	1	distribution	distribution	NOUN
easat-267	143	2	of	of	ADP
easat-267	143	3	sickle	sickle	NOUN
easat-267	143	4	cell	cell	NOUN
easat-267	143	5	trait	trait	NOUN
easat-267	143	6	and	and	CCONJ
easat-267	143	7	g6pd	g6pd	NOUN
easat-267	143	8	deficiency	deficiency	NOUN
easat-267	143	9	in	in	ADP
easat-267	143	10	scheduled	scheduled	ADJ
easat-267	143	11	caste	caste	NOUN
easat-267	143	12	and	and	CCONJ
easat-267	143	13	scheduled	schedule	VERB
easat-267	143	14	tribe	tribe	NOUN
easat-267	143	15	communities	community	NOUN
easat-267	143	16	of	of	ADP
easat-267	143	17	madhya	madhya	PROPN
easat-267	143	18	pradesh	pradesh	PROPN
easat-267	143	19	,	,	PUNCT
easat-267	143	20	india	india	PROPN
easat-267	143	21	.	.	PUNCT
easat-267	144	1	tribe	tribe	PROPN
easat-267	144	2	district	district	PROPN
easat-267	144	3	n	n	CCONJ
easat-267	144	4	sickle	sickle	NOUN
easat-267	144	5	cell	cell	NOUN
easat-267	144	6	trait	trait	NOUN
easat-267	144	7	g6pd	g6pd	NOUN
easat-267	144	8	deficiency	deficiency	NOUN
easat-267	144	9	male	male	ADJ
easat-267	144	10	male+female	male+female	PROPN
easat-267	144	11	n	n	CCONJ
easat-267	144	12	%	%	NOUN
easat-267	144	13	n	n	PRON
easat-267	144	14	%	%	NOUN
easat-267	144	15	n	n	PRON
easat-267	144	16	%	%	NOUN
easat-267	144	17	primitive	primitive	ADJ
easat-267	144	18	tribe	tribe	NOUN
easat-267	144	19	baiga	baiga	ADJ
easat-267	144	20	mandla	mandla	NOUN
easat-267	144	21	1566	1566	NUM
easat-267	144	22	244	244	NUM
easat-267	144	23	15.6	15.6	NUM
easat-267	144	24	25	25	NUM
easat-267	144	25	4.5	4.5	NUM
easat-267	144	26	baiga	baiga	ADJ
easat-267	144	27	dindori	dindori	NOUN
easat-267	144	28	990	990	NUM
easat-267	144	29	182	182	NUM
easat-267	144	30	18.4	18.4	NUM
easat-267	144	31	34	34	NUM
easat-267	144	32	3.4	3.4	NUM
easat-267	144	33	baiga	baiga	NOUN
easat-267	144	34	shahdol	shahdol	VERB
easat-267	144	35	219	219	NUM
easat-267	144	36	23	23	NUM
easat-267	144	37	10.5	10.5	NUM
easat-267	144	38	4	4	NUM
easat-267	144	39	1.8	1.8	NUM
easat-267	144	40	bharia	bharia	NOUN
easat-267	144	41	chhindwara	chhindwara	NOUN
easat-267	144	42	(	(	PUNCT
easat-267	144	43	inside	inside	ADV
easat-267	144	44	)	)	PUNCT
easat-267	144	45	183	183	NUM
easat-267	144	46	24	24	NUM
easat-267	144	47	13.2	13.2	NUM
easat-267	144	48	22	22	NUM
easat-267	144	49	12.1	12.1	NUM
easat-267	144	50	bharia	bharia	NOUN
easat-267	144	51	chhindwara	chhindwara	NOUN
easat-267	144	52	(	(	PUNCT
easat-267	144	53	outside	outside	ADV
easat-267	144	54	)	)	PUNCT
easat-267	144	55	102	102	NUM
easat-267	144	56	3	3	NUM
easat-267	144	57	2.9	2.9	NUM
easat-267	144	58	9	9	NUM
easat-267	144	59	8.3	8.3	NUM
easat-267	144	60	scheduled	schedule	VERB
easat-267	144	61	tribe	tribe	NOUN
easat-267	144	62	barela	barela	NOUN
easat-267	144	63	khargone	khargone	PROPN
easat-267	144	64	345	345	NUM
easat-267	144	65	88	88	NUM
easat-267	144	66	25.5	25.5	NUM
easat-267	144	67	18	18	NUM
easat-267	144	68	5.8	5.8	NUM
easat-267	144	69	barela	barela	NOUN
easat-267	144	70	nimar	nimar	VERB
easat-267	144	71	316	316	NUM
easat-267	144	72	86	86	NUM
easat-267	144	73	27.2	27.2	NUM
easat-267	144	74	18	18	NUM
easat-267	144	75	5.7	5.7	NUM
easat-267	144	76	bhil	bhil	NOUN
easat-267	144	77	jhabua	jhabua	PROPN
easat-267	144	78	904	904	NUM
easat-267	144	79	183	183	NUM
easat-267	144	80	20	20	NUM
easat-267	144	81	8	8	NUM
easat-267	144	82	6.7	6.7	NUM
easat-267	144	83	bhil	bhil	NOUN
easat-267	144	84	ratlam	ratlam	VERB
easat-267	144	85	433	433	NUM
easat-267	144	86	51	51	NUM
easat-267	144	87	11.8	11.8	NUM
easat-267	144	88	15	15	NUM
easat-267	144	89	3.4	3.4	NUM
easat-267	144	90	bhil	bhil	NOUN
easat-267	144	91	nimar	nimar	VERB
easat-267	144	92	316	316	NUM
easat-267	144	93	45	45	NUM
easat-267	144	94	14.2	14.2	NUM
easat-267	144	95	34	34	NUM
easat-267	144	96	4.5	4.5	NUM
easat-267	144	97	bhilala	bhilala	PROPN
easat-267	144	98	jhabua	jhabua	PROPN
easat-267	144	99	403	403	NUM
easat-267	144	100	123	123	NUM
easat-267	144	101	30.5	30.5	NUM
easat-267	144	102	23	23	NUM
easat-267	144	103	7.2	7.2	NUM
easat-267	144	104	bhilala	bhilala	NOUN
easat-267	144	105	nimar	nimar	VERB
easat-267	144	106	370	370	NUM
easat-267	144	107	68	68	NUM
easat-267	144	108	18.4	18.4	NUM
easat-267	144	109	16	16	NUM
easat-267	144	110	4.3	4.3	NUM
easat-267	144	111	gond	gond	PROPN
easat-267	144	112	betul	betul	PROPN
easat-267	144	113	299	299	NUM
easat-267	144	114	34	34	NUM
easat-267	144	115	11.4	11.4	NUM
easat-267	144	116	9	9	NUM
easat-267	144	117	3	3	NUM
easat-267	144	118	gond	gond	NOUN
easat-267	144	119	damoh	damoh	NOUN
easat-267	144	120	321	321	NUM
easat-267	144	121	106	106	NUM
easat-267	144	122	33	33	NUM
easat-267	144	123	30	30	NUM
easat-267	144	124	9.3	9.3	NUM
easat-267	144	125	gond	gond	PROPN
easat-267	144	126	jabalpur	jabalpur	PROPN
easat-267	144	127	3224	3224	NUM
easat-267	144	128	612	612	NUM
easat-267	144	129	19	19	NUM
easat-267	144	130	0	0	NUM
easat-267	144	131	0	0	NUM
easat-267	145	1	gond	gond	PROPN
easat-267	145	2	mandla	mandla	NOUN
easat-267	145	3	280	280	NUM
easat-267	145	4	52	52	NUM
easat-267	145	5	18.6	18.6	NUM
easat-267	145	6	0	0	NUM
easat-267	145	7	0	0	NUM
easat-267	145	8	gond	gond	PROPN
easat-267	145	9	chhindwara	chhindwara	PROPN
easat-267	145	10	(	(	PUNCT
easat-267	145	11	inside	inside	ADV
easat-267	145	12	)	)	PUNCT
easat-267	145	13	75	75	NUM
easat-267	145	14	15	15	NUM
easat-267	145	15	4.3	4.3	NUM
easat-267	145	16	3	3	NUM
easat-267	145	17	3.7	3.7	NUM
easat-267	145	18	gond	gond	NOUN
easat-267	145	19	chhindwara	chhindwara	PROPN
easat-267	145	20	(	(	PUNCT
easat-267	145	21	outside	outside	ADV
easat-267	145	22	)	)	PUNCT
easat-267	145	23	158	158	NUM
easat-267	145	24	25	25	NUM
easat-267	145	25	15.8	15.8	NUM
easat-267	145	26	5	5	NUM
easat-267	145	27	3.1	3.1	NUM
easat-267	145	28	gond	gond	NOUN
easat-267	145	29	chhindwara	chhindwara	NOUN
easat-267	145	30	83	83	NUM
easat-267	145	31	10	10	NUM
easat-267	145	32	12	12	NUM
easat-267	145	33	3	3	NUM
easat-267	145	34	3.1	3.1	NUM
easat-267	145	35	gond	gond	NOUN
easat-267	145	36	seoni	seoni	VERB
easat-267	145	37	286	286	NUM
easat-267	145	38	54	54	NUM
easat-267	145	39	18.9	18.9	NUM
easat-267	145	40	5	5	NUM
easat-267	145	41	1.7	1.7	NUM
easat-267	145	42	gond	gond	NOUN
easat-267	145	43	shahdol	shahdol	VERB
easat-267	145	44	252	252	NUM
easat-267	145	45	33	33	NUM
easat-267	145	46	13.1	13.1	NUM
easat-267	145	47	8	8	NUM
easat-267	145	48	3.2	3.2	NUM
easat-267	145	49	gond	gond	NOUN
easat-267	145	50	balaghat	balaghat	PROPN
easat-267	146	1	311	311	NUM
easat-267	146	2	48	48	NUM
easat-267	146	3	15.4	15.4	NUM
easat-267	146	4	4	4	NUM
easat-267	146	5	1.3	1.3	NUM
easat-267	146	6	kol	kol	PROPN
easat-267	146	7	satna	satna	VERB
easat-267	146	8	290	290	NUM
easat-267	146	9	12	12	NUM
easat-267	146	10	4.1	4.1	NUM
easat-267	146	11	13	13	NUM
easat-267	146	12	4.5	4.5	NUM
easat-267	146	13	korku	korku	NOUN
easat-267	146	14	chhindwara	chhindwara	NOUN
easat-267	146	15	250	250	NUM
easat-267	146	16	43	43	NUM
easat-267	146	17	17.2	17.2	NUM
easat-267	146	18	14	14	NUM
easat-267	146	19	5.6	5.6	NUM
easat-267	146	20	korku	korku	NOUN
easat-267	146	21	khandwa	khandwa	PROPN
easat-267	146	22	301	301	NUM
easat-267	146	23	51	51	NUM
easat-267	146	24	16.9	16.9	NUM
easat-267	146	25	4	4	NUM
easat-267	146	26	1.3	1.3	NUM
easat-267	146	27	korku	korku	NOUN
easat-267	146	28	betul	betul	PROPN
easat-267	146	29	296	296	NUM
easat-267	146	30	41	41	NUM
easat-267	146	31	13.8	13.8	NUM
easat-267	146	32	8	8	NUM
easat-267	146	33	2.7	2.7	NUM
easat-267	146	34	panika	panika	NOUN
easat-267	146	35	shahdol	shahdol	VERB
easat-267	146	36	210	210	NUM
easat-267	146	37	60	60	NUM
easat-267	146	38	28.6	28.6	NUM
easat-267	146	39	6	6	NUM
easat-267	146	40	2.8	2.8	NUM
easat-267	146	41	pradhan	pradhan	NOUN
easat-267	146	42	dindori	dindori	NOUN
easat-267	146	43	990	990	NUM
easat-267	146	44	182	182	NUM
easat-267	146	45	18.4	18.4	NUM
easat-267	146	46	11	11	NUM
easat-267	146	47	4.9	4.9	NUM
easat-267	146	48	patelia	patelia	NOUN
easat-267	146	49	jhabua	jhabua	PROPN
easat-267	146	50	166	166	NUM
easat-267	146	51	34	34	NUM
easat-267	146	52	20.5	20.5	NUM
easat-267	146	53	4	4	NUM
easat-267	146	54	2.6	2.6	NUM
easat-267	146	55	raj	raj	PROPN
easat-267	146	56	gond	gond	PROPN
easat-267	146	57	damoh	damoh	PROPN
easat-267	146	58	321	321	NUM
easat-267	146	59	33	33	NUM
easat-267	146	60	10.3	10.3	NUM
easat-267	146	61	96	96	NUM
easat-267	146	62	30	30	NUM
easat-267	146	63	balai	balai	PROPN
easat-267	146	64	khandwa	khandwa	PROPN
easat-267	146	65	276	276	NUM
easat-267	146	66	39	39	NUM
easat-267	146	67	14.1	14.1	NUM
easat-267	146	68	2	2	NUM
easat-267	146	69	0.7	0.7	NUM
easat-267	146	70	basod	basod	NOUN
easat-267	146	71	betul	betul	PROPN
easat-267	146	72	123	123	NUM
easat-267	146	73	24	24	NUM
easat-267	146	74	19.5	19.5	NUM
easat-267	146	75	3	3	NUM
easat-267	146	76	2.4	2.4	NUM
easat-267	146	77	basod	basod	NOUN
easat-267	146	78	chhindwara	chhindwara	NOUN
easat-267	146	79	150	150	NUM
easat-267	146	80	33	33	NUM
easat-267	146	81	22	22	NUM
easat-267	146	82	0	0	NUM
easat-267	146	83	0	0	NUM
easat-267	146	84	choudhury	choudhury	PROPN
easat-267	146	85	(	(	PUNCT
easat-267	146	86	chamar	chamar	PROPN
easat-267	146	87	)	)	PUNCT
easat-267	146	88	damoh	damoh	VERB
easat-267	146	89	339	339	NUM
easat-267	146	90	61	61	NUM
easat-267	146	91	18	18	NUM
easat-267	146	92	6	6	NUM
easat-267	146	93	1.8	1.8	NUM
easat-267	146	94	choudhury	choudhury	PROPN
easat-267	146	95	(	(	PUNCT
easat-267	146	96	chamar	chamar	PROPN
easat-267	146	97	)	)	PUNCT
easat-267	146	98	shahdol	shahdol	VERB
easat-267	146	99	195	195	NUM
easat-267	146	100	10	10	NUM
easat-267	146	101	5.1	5.1	NUM
easat-267	146	102	5	5	NUM
easat-267	146	103	2.6	2.6	NUM
easat-267	146	104	jharia	jharia	PROPN
easat-267	146	105	jabalpur	jabalpur	PROPN
easat-267	146	106	637	637	NUM
easat-267	146	107	28	28	NUM
easat-267	146	108	4.4	4.4	NUM
easat-267	146	109	0	0	NUM
easat-267	146	110	0	0	NUM
easat-267	146	111	jharia	jharia	PROPN
easat-267	146	112	jabalpur	jabalpur	PROPN
easat-267	146	113	409	409	NUM
easat-267	146	114	155	155	NUM
easat-267	146	115	37.9	37.9	NUM
easat-267	146	116	0	0	NUM
easat-267	146	117	0	0	NUM
easat-267	146	118	katiya	katiya	NOUN
easat-267	146	119	chhindwara	chhindwara	PROPN
easat-267	146	120	181	181	NUM
easat-267	146	121	45	45	NUM
easat-267	146	122	24.9	24.9	NUM
easat-267	146	123	7	7	NUM
easat-267	146	124	2	2	NUM
easat-267	146	125	mehra	mehra	PROPN
easat-267	146	126	betul	betul	PROPN
easat-267	146	127	352	352	NUM
easat-267	146	128	114	114	NUM
easat-267	146	129	32.4	32.4	NUM
easat-267	146	130	7	7	NUM
easat-267	146	131	2	2	NUM
easat-267	146	132	mehra	mehra	PROPN
easat-267	146	133	chhindwara	chhindwara	PROPN
easat-267	146	134	114	114	NUM
easat-267	146	135	23	23	NUM
easat-267	146	136	19.8	19.8	NUM
easat-267	146	137	3	3	NUM
easat-267	146	138	2.6	2.6	NUM
easat-267	146	139	mehra	mehra	PROPN
easat-267	146	140	seoni	seoni	VERB
easat-267	146	141	216	216	NUM
easat-267	146	142	46	46	NUM
easat-267	146	143	21.3	21.3	NUM
easat-267	146	144	4	4	NUM
easat-267	146	145	1.8	1.8	NUM
easat-267	146	146	mehra	mehra	PROPN
easat-267	146	147	balaghat	balaghat	PROPN
easat-267	146	148	219	219	NUM
easat-267	146	149	40	40	NUM
easat-267	146	150	18.3	18.3	NUM
easat-267	146	151	3	3	NUM
easat-267	146	152	1.4	1.4	NUM
easat-267	146	153	other	other	ADJ
easat-267	146	154	backward	backward	ADJ
easat-267	146	155	class	class	NOUN
easat-267	146	156	chhindwara	chhindwara	NOUN
easat-267	146	157	58	58	NUM
easat-267	146	158	7	7	NUM
easat-267	146	159	12.1	12.1	NUM
easat-267	146	160	4	4	NUM
easat-267	146	161	6.9	6.9	NUM
easat-267	146	162	chemical	chemical	NOUN
easat-267	146	163	reactions	reaction	NOUN
easat-267	146	164	,	,	PUNCT
easat-267	146	165	involving	involve	VERB
easat-267	146	166	g6pd	g6pd	X
easat-267	146	167	,	,	PUNCT
easat-267	146	168	produce	produce	VERB
easat-267	146	169	compounds	compound	NOUN
easat-267	146	170	that	that	PRON
easat-267	146	171	prevent	prevent	VERB
easat-267	146	172	reactive	reactive	ADJ
easat-267	146	173	oxygen	oxygen	NOUN
easat-267	146	174	species	specie	NOUN
easat-267	146	175	from	from	ADP
easat-267	146	176	building	build	VERB
easat-267	146	177	up	up	ADP
easat-267	146	178	to	to	ADP
easat-267	146	179	toxic	toxic	ADJ
easat-267	146	180	levels	level	NOUN
easat-267	146	181	within	within	ADP
easat-267	146	182	red	red	ADJ
easat-267	146	183	blood	blood	NOUN
easat-267	146	184	cells	cell	NOUN
easat-267	146	185	.	.	PUNCT
easat-267	147	1	in	in	ADP
easat-267	147	2	affected	affect	VERB
easat-267	147	3	individuals	individual	NOUN
easat-267	147	4	,	,	PUNCT
easat-267	147	5	a	a	DET
easat-267	147	6	defect	defect	NOUN
easat-267	147	7	in	in	ADP
easat-267	147	8	g6pd	g6pd	NOUN
easat-267	147	9	enzyme	enzyme	NOUN
easat-267	147	10	causes	cause	VERB
easat-267	147	11	red	red	ADJ
easat-267	147	12	blood	blood	NOUN
easat-267	147	13	cells	cell	NOUN
easat-267	147	14	to	to	PART
easat-267	147	15	break	break	VERB
easat-267	147	16	down	down	ADP
easat-267	147	17	,	,	PUNCT
easat-267	147	18	called	call	VERB
easat-267	147	19	hemolysis	hemolysis	NOUN
easat-267	147	20	,	,	PUNCT
easat-267	147	21	prematurely	prematurely	ADV
easat-267	147	22	faster	fast	ADV
easat-267	147	23	than	than	SCONJ
easat-267	147	24	the	the	DET
easat-267	147	25	body	body	NOUN
easat-267	147	26	can	can	AUX
easat-267	147	27	replace	replace	VERB
easat-267	147	28	them	they	PRON
easat-267	147	29	[	[	X
easat-267	147	30	30	30	NUM
easat-267	147	31	]	]	PUNCT
easat-267	147	32	.	.	PUNCT
easat-267	148	1	once	once	ADV
easat-267	148	2	g6pd	g6pd	NOUN
easat-267	148	3	deficiency	deficiency	NOUN
easat-267	148	4	has	have	AUX
easat-267	148	5	progressed	progress	VERB
easat-267	148	6	to	to	ADP
easat-267	148	7	hemolytic	hemolytic	ADJ
easat-267	148	8	anemia	anemia	NOUN
easat-267	148	9	,	,	PUNCT
easat-267	148	10	more	more	ADV
easat-267	148	11	aggressive	aggressive	ADJ
easat-267	148	12	treatment	treatment	NOUN
easat-267	148	13	may	may	AUX
easat-267	148	14	be	be	AUX
easat-267	148	15	required	require	VERB
easat-267	148	16	.	.	PUNCT
easat-267	149	1	this	this	PRON
easat-267	149	2	usually	usually	ADV
easat-267	149	3	includes	include	VERB
easat-267	149	4	oxygen	oxygen	NOUN
easat-267	149	5	therapy	therapy	NOUN
easat-267	149	6	and	and	CCONJ
easat-267	149	7	blood	blood	NOUN
easat-267	149	8	transfusion	transfusion	NOUN
easat-267	149	9	to	to	PART
easat-267	149	10	replenish	replenish	VERB
easat-267	149	11	oxygen	oxygen	NOUN
easat-267	149	12	and	and	CCONJ
easat-267	149	13	red	red	ADJ
easat-267	149	14	blood	blood	NOUN
easat-267	149	15	cells	cell	NOUN
easat-267	149	16	.	.	PUNCT
easat-267	150	1	the	the	DET
easat-267	150	2	affected	affected	ADJ
easat-267	150	3	person	person	NOUN
easat-267	150	4	will	will	AUX
easat-267	150	5	need	need	VERB
easat-267	150	6	to	to	PART
easat-267	150	7	stay	stay	VERB
easat-267	150	8	in	in	ADP
easat-267	150	9	the	the	DET
easat-267	150	10	hospital	hospital	NOUN
easat-267	150	11	,	,	PUNCT
easat-267	150	12	while	while	SCONJ
easat-267	150	13	receiving	receive	VERB
easat-267	150	14	these	these	DET
easat-267	150	15	treatments	treatment	NOUN
easat-267	150	16	as	as	ADP
easat-267	150	17	close	close	ADJ
easat-267	150	18	monitoring	monitoring	NOUN
easat-267	150	19	required	require	VERB
easat-267	150	20	of	of	ADP
easat-267	150	21	severe	severe	ADJ
easat-267	150	22	hemolytic	hemolytic	ADJ
easat-267	150	23	anemia	anemia	NOUN
easat-267	150	24	,	,	PUNCT
easat-267	150	25	and	and	CCONJ
easat-267	150	26	is	be	AUX
easat-267	150	27	critical	critical	ADJ
easat-267	150	28	for	for	ADP
easat-267	150	29	ensuring	ensure	VERB
easat-267	150	30	a	a	DET
easat-267	150	31	full	full	ADJ
easat-267	150	32	recovery	recovery	NOUN
easat-267	150	33	without	without	ADP
easat-267	150	34	complications	complication	NOUN
easat-267	150	35	.	.	PUNCT
easat-267	151	1	in	in	ADP
easat-267	151	2	people	people	NOUN
easat-267	151	3	with	with	ADP
easat-267	151	4	g6pd	g6pd	NOUN
easat-267	151	5	deficiency	deficiency	NOUN
easat-267	151	6	,	,	PUNCT
easat-267	151	7	hemolytic	hemolytic	ADJ
easat-267	151	8	anemia	anemia	NOUN
easat-267	151	9	is	be	AUX
easat-267	151	10	most	most	ADV
easat-267	151	11	often	often	ADV
easat-267	151	12	triggered	trigger	VERB
easat-267	151	13	by	by	ADP
easat-267	151	14	bacterial	bacterial	ADJ
easat-267	151	15	or	or	CCONJ
easat-267	151	16	viral	viral	ADJ
easat-267	151	17	infections	infection	NOUN
easat-267	151	18	or	or	CCONJ
easat-267	151	19	by	by	ADP
easat-267	151	20	certain	certain	ADJ
easat-267	151	21	drugs	drug	NOUN
easat-267	151	22	(	(	PUNCT
easat-267	151	23	such	such	ADJ
easat-267	151	24	as	as	ADP
easat-267	151	25	some	some	DET
easat-267	151	26	antibiotics	antibiotic	NOUN
easat-267	151	27	and	and	CCONJ
easat-267	151	28	medications	medication	NOUN
easat-267	151	29	used	use	VERB
easat-267	151	30	to	to	PART
easat-267	151	31	treat	treat	VERB
easat-267	151	32	malaria	malaria	NOUN
easat-267	151	33	)	)	PUNCT
easat-267	151	34	.	.	PUNCT
easat-267	152	1	hemolytic	hemolytic	ADJ
easat-267	152	2	anemia	anemia	NOUN
easat-267	152	3	can	can	AUX
easat-267	152	4	also	also	ADV
easat-267	152	5	occur	occur	VERB
easat-267	152	6	after	after	ADP
easat-267	152	7	eating	eat	VERB
easat-267	152	8	fava	fava	NOUN
easat-267	152	9	beans	bean	NOUN
easat-267	152	10	or	or	CCONJ
easat-267	152	11	inhaling	inhale	VERB
easat-267	152	12	pollen	pollen	NOUN
easat-267	152	13	from	from	ADP
easat-267	152	14	fava	fava	NOUN
easat-267	152	15	plants	plant	NOUN
easat-267	152	16	(	(	PUNCT
easat-267	152	17	a	a	DET
easat-267	152	18	reaction	reaction	NOUN
easat-267	152	19	called	call	VERB
easat-267	152	20	favism	favism	NOUN
easat-267	152	21	)	)	PUNCT
easat-267	153	1	[	[	X
easat-267	153	2	2,9	2,9	NUM
easat-267	153	3	]	]	PUNCT
easat-267	153	4	.	.	PUNCT
easat-267	154	1	it	it	PRON
easat-267	154	2	may	may	AUX
easat-267	154	3	also	also	ADV
easat-267	154	4	be	be	AUX
easat-267	154	5	triggered	trigger	VERB
easat-267	154	6	by	by	ADP
easat-267	154	7	infections	infection	NOUN
easat-267	154	8	or	or	CCONJ
easat-267	154	9	by	by	ADP
easat-267	154	10	certain	certain	ADJ
easat-267	154	11	drugs	drug	NOUN
easat-267	154	12	such	such	ADJ
easat-267	154	13	as	as	ADP
easat-267	154	14	:	:	PUNCT
easat-267	154	15	•	•	NUM
easat-267	154	16	antimalarials	antimalarial	NOUN
easat-267	154	17	,	,	PUNCT
easat-267	154	18	a	a	DET
easat-267	154	19	type	type	NOUN
easat-267	154	20	of	of	ADP
easat-267	154	21	medication	medication	NOUN
easat-267	154	22	used	use	VERB
easat-267	154	23	to	to	PART
easat-267	154	24	prevent	prevent	VERB
easat-267	154	25	and	and	CCONJ
easat-267	154	26	treat	treat	VERB
easat-267	154	27	malaria	malaria	NOUN
easat-267	154	28	•	•	NOUN
easat-267	154	29	sulfonamides	sulfonamide	NOUN
easat-267	154	30	,	,	PUNCT
easat-267	154	31	a	a	DET
easat-267	154	32	medication	medication	NOUN
easat-267	154	33	used	use	VERB
easat-267	154	34	for	for	ADP
easat-267	154	35	treating	treat	VERB
easat-267	154	36	various	various	ADJ
easat-267	154	37	infections	infection	NOUN
easat-267	154	38	•	•	ADP
easat-267	154	39	aspirin	aspirin	NOUN
easat-267	154	40	,	,	PUNCT
easat-267	154	41	a	a	DET
easat-267	154	42	drug	drug	NOUN
easat-267	154	43	used	use	VERB
easat-267	154	44	for	for	ADP
easat-267	154	45	relieving	relieve	VERB
easat-267	154	46	fever	fever	NOUN
easat-267	154	47	,	,	PUNCT
easat-267	154	48	pain	pain	NOUN
easat-267	154	49	and	and	CCONJ
easat-267	154	50	swelling	swell	VERB
easat-267	154	51	•	•	NOUN
easat-267	154	52	some	some	DET
easat-267	154	53	non	non	ADJ
easat-267	154	54	-	-	ADJ
easat-267	154	55	steroidal	steroidal	ADJ
easat-267	154	56	anti	anti	ADJ
easat-267	154	57	-	-	ADJ
easat-267	154	58	inflammatory	inflammatory	ADJ
easat-267	154	59	medications	medication	NOUN
easat-267	154	60	(	(	PUNCT
easat-267	154	61	nsaids	nsaid	NOUN
easat-267	154	62	)	)	PUNCT
easat-267	154	63	.	.	PUNCT
easat-267	155	1	49	49	NUM
easat-267	155	2	edelweiss	edelweiss	PROPN
easat-267	155	3	applied	apply	VERB
easat-267	155	4	science	science	NOUN
easat-267	155	5	and	and	CCONJ
easat-267	155	6	technology	technology	NOUN
easat-267	155	7	issn	issn	PROPN
easat-267	155	8	:	:	PUNCT
easat-267	155	9	2576	2576	NUM
easat-267	155	10	-	-	SYM
easat-267	155	11	8484	8484	NUM
easat-267	155	12	vol	vol	NOUN
easat-267	155	13	.	.	PROPN
easat-267	156	1	3	3	NUM
easat-267	156	2	,	,	PUNCT
easat-267	156	3	no	no	INTJ
easat-267	156	4	.	.	NOUN
easat-267	156	5	1	1	NUM
easat-267	156	6	:	:	SYM
easat-267	156	7	44	44	NUM
easat-267	156	8	-	-	SYM
easat-267	156	9	52	52	NUM
easat-267	156	10	,	,	PUNCT
easat-267	156	11	2019	2019	NUM
easat-267	156	12	doi	doi	NOUN
easat-267	156	13	:	:	PUNCT
easat-267	156	14	10.33805/2576	10.33805/2576	NUM
easat-267	156	15	-	-	SYM
easat-267	156	16	8484.167	8484.167	NUM
easat-267	156	17	©	©	PROPN
easat-267	156	18	2019	2019	NUM
easat-267	156	19	by	by	ADP
easat-267	156	20	the	the	DET
easat-267	156	21	author	author	NOUN
easat-267	156	22	table	table	NOUN
easat-267	156	23	4	4	NUM
easat-267	156	24	.	.	PUNCT
easat-267	157	1	distribution	distribution	NOUN
easat-267	157	2	of	of	ADP
easat-267	157	3	sickle	sickle	NOUN
easat-267	157	4	cell	cell	NOUN
easat-267	157	5	trait	trait	NOUN
easat-267	157	6	and	and	CCONJ
easat-267	157	7	g6pd	g6pd	NOUN
easat-267	157	8	deficiency	deficiency	NOUN
easat-267	157	9	in	in	ADP
easat-267	157	10	scheduled	scheduled	ADJ
easat-267	157	11	caste	caste	NOUN
easat-267	157	12	and	and	CCONJ
easat-267	157	13	scheduled	schedule	VERB
easat-267	157	14	tribe	tribe	NOUN
easat-267	157	15	communities	community	NOUN
easat-267	157	16	of	of	ADP
easat-267	157	17	maharashtra	maharashtra	PROPN
easat-267	157	18	,	,	PUNCT
easat-267	157	19	india	india	PROPN
easat-267	157	20	.	.	PUNCT
easat-267	158	1	tribe	tribe	PROPN
easat-267	158	2	district	district	PROPN
easat-267	158	3	sickle	sickle	PROPN
easat-267	158	4	cell	cell	NOUN
easat-267	158	5	trait	trait	NOUN
easat-267	158	6	*	*	PUNCT
easat-267	158	7	n	n	CCONJ
easat-267	158	8	g6pd	g6pd	NOUN
easat-267	158	9	deficiency	deficiency	NOUN
easat-267	158	10	male	male	ADJ
easat-267	158	11	male+female	male+female	PROPN
easat-267	158	12	n	n	CCONJ
easat-267	158	13	%	%	NOUN
easat-267	159	1	n	n	PRON
easat-267	159	2	%	%	NOUN
easat-267	160	1	n	n	PRON
easat-267	160	2	%	%	NOUN
easat-267	160	3	reference	reference	NOUN
easat-267	160	4	scheduled	schedule	VERB
easat-267	160	5	tribe	tribe	NOUN
easat-267	160	6	andha	andha	PROPN
easat-267	160	7	nanded	nande	VERB
easat-267	160	8	2	2	NUM
easat-267	160	9	bhil	bhil	NOUN
easat-267	160	10	nandurbar	nandurbar	VERB
easat-267	160	11	20.6	20.6	NUM
easat-267	160	12	215	215	NUM
easat-267	160	13	16	16	NUM
easat-267	160	14	7.4	7.4	NUM
easat-267	160	15	2	2	NUM
easat-267	160	16	gond	gond	NOUN
easat-267	160	17	,	,	PUNCT
easat-267	160	18	madia	madia	PROPN
easat-267	160	19	gadehiroli	gadehiroli	PROPN
easat-267	160	20	yeotmal	yeotmal	PROPN
easat-267	160	21	20.8	20.8	NUM
easat-267	160	22	135	135	NUM
easat-267	160	23	24	24	NUM
easat-267	160	24	19.4	19.4	NUM
easat-267	160	25	2	2	NUM
easat-267	160	26	halbi	halbi	PROPN
easat-267	160	27	gadchiroli	gadchiroli	PROPN
easat-267	160	28	13.9	13.9	NUM
easat-267	160	29	katkari	katkari	PROPN
easat-267	160	30	pune	pune	NOUN
easat-267	160	31	,	,	PUNCT
easat-267	160	32	raigad	raigad	NOUN
easat-267	160	33	,	,	PUNCT
easat-267	160	34	ratnagiri	ratnagiri	ADV
easat-267	160	35	5.9	5.9	NUM
easat-267	160	36	77	77	NUM
easat-267	160	37	6	6	NUM
easat-267	160	38	7.8	7.8	NUM
easat-267	160	39	2	2	NUM
easat-267	160	40	kokana	kokana	NOUN
easat-267	160	41	dhule	dhule	NOUN
easat-267	160	42	,	,	PUNCT
easat-267	160	43	nasik	nasik	PROPN
easat-267	160	44	3.5	3.5	NUM
easat-267	160	45	83	83	NUM
easat-267	160	46	7	7	NUM
easat-267	160	47	8.4	8.4	NUM
easat-267	160	48	2	2	NUM
easat-267	160	49	kolam	kolam	PROPN
easat-267	160	50	yeotmal	yeotmal	PROPN
easat-267	160	51	8.3	8.3	NUM
easat-267	160	52	korku	korku	PROPN
easat-267	160	53	amravati	amravati	PROPN
easat-267	160	54	9.5	9.5	NUM
easat-267	160	55	mahadeo	mahadeo	PROPN
easat-267	160	56	koli	koli	PROPN
easat-267	160	57	pune	pune	PROPN
easat-267	160	58	,	,	PUNCT
easat-267	160	59	nasik	nasik	PROPN
easat-267	160	60	0.8	0.8	NUM
easat-267	160	61	malhar	malhar	PROPN
easat-267	160	62	koli	koli	PROPN
easat-267	160	63	thane	thane	PROPN
easat-267	160	64	13.9	13.9	NUM
easat-267	160	65	687	687	NUM
easat-267	160	66	21	21	NUM
easat-267	160	67	3.1	3.1	NUM
easat-267	160	68	2	2	NUM
easat-267	160	69	otkar	otkar	ADP
easat-267	160	70	gadchiroli	gadchiroli	NOUN
easat-267	160	71	35	35	NUM
easat-267	160	72	pardhan	pardhan	NOUN
easat-267	160	73	nanded	nanded	PROPN
easat-267	160	74	,	,	PUNCT
easat-267	160	75	yeotmal	yeotmal	NOUN
easat-267	160	76	33.7	33.7	NUM
easat-267	160	77	pawara	pawara	NOUN
easat-267	160	78	dhule	dhule	NOUN
easat-267	160	79	,	,	PUNCT
easat-267	160	80	jalgaon	jalgaon	PROPN
easat-267	160	81	25.2	25.2	NUM
easat-267	160	82	87	87	NUM
easat-267	160	83	3	3	NUM
easat-267	160	84	3.5	3.5	NUM
easat-267	160	85	2	2	NUM
easat-267	160	86	raj	raj	NOUN
easat-267	160	87	gond	gond	PROPN
easat-267	160	88	gadchiroli	gadchiroli	PROPN
easat-267	160	89	10.9	10.9	NUM
easat-267	160	90	tandvi	tandvi	NOUN
easat-267	160	91	jalgaon	jalgaon	PROPN
easat-267	160	92	8.3	8.3	NUM
easat-267	160	93	thakur	thakur	PROPN
easat-267	160	94	ahmednagar	ahmednagar	NOUN
easat-267	160	95	,	,	PUNCT
easat-267	160	96	pune	pune	NOUN
easat-267	160	97	,	,	PUNCT
easat-267	160	98	aigad	aigad	NOUN
easat-267	160	99	,	,	PUNCT
easat-267	160	100	thane	thane	NOUN
easat-267	160	101	0	0	NUM
easat-267	160	102	warli	warli	NOUN
easat-267	160	103	thane	thane	NOUN
easat-267	160	104	8	8	NUM
easat-267	160	105	656	656	NUM
easat-267	160	106	112	112	NUM
easat-267	160	107	17	17	NUM
easat-267	160	108	2	2	NUM
easat-267	160	109	warli	warli	NOUN
easat-267	160	110	thane	thane	NOUN
easat-267	160	111	128	128	NUM
easat-267	160	112	25	25	NUM
easat-267	160	113	19.5	19.5	NUM
easat-267	160	114	2	2	NUM
easat-267	160	115	once	once	SCONJ
easat-267	160	116	the	the	DET
easat-267	160	117	underlying	underlying	ADJ
easat-267	160	118	cause	cause	NOUN
easat-267	160	119	is	be	AUX
easat-267	160	120	treated	treat	VERB
easat-267	160	121	or	or	CCONJ
easat-267	160	122	resolved	resolve	VERB
easat-267	160	123	,	,	PUNCT
easat-267	160	124	symptoms	symptom	NOUN
easat-267	160	125	of	of	ADP
easat-267	160	126	g6pd	g6pd	NOUN
easat-267	160	127	deficiency	deficiency	NOUN
easat-267	160	128	usually	usually	ADV
easat-267	160	129	disappear	disappear	VERB
easat-267	160	130	within	within	ADP
easat-267	160	131	a	a	DET
easat-267	160	132	few	few	ADJ
easat-267	160	133	weeks	week	NOUN
easat-267	160	134	.	.	PUNCT
easat-267	161	1	g6pd	g6pd	NOUN
easat-267	161	2	deficiency	deficiency	NOUN
easat-267	161	3	is	be	AUX
easat-267	161	4	also	also	ADV
easat-267	161	5	a	a	DET
easat-267	161	6	significant	significant	ADJ
easat-267	161	7	cause	cause	NOUN
easat-267	161	8	of	of	ADP
easat-267	161	9	mild	mild	NOUN
easat-267	161	10	to	to	ADP
easat-267	161	11	severe	severe	ADJ
easat-267	161	12	jaundice	jaundice	NOUN
easat-267	161	13	in	in	ADP
easat-267	161	14	newborns	newborn	NOUN
easat-267	161	15	.	.	PUNCT
easat-267	162	1	many	many	ADJ
easat-267	162	2	people	people	NOUN
easat-267	162	3	with	with	ADP
easat-267	162	4	this	this	DET
easat-267	162	5	disorder	disorder	NOUN
easat-267	162	6	,	,	PUNCT
easat-267	162	7	however	however	ADV
easat-267	162	8	,	,	PUNCT
easat-267	162	9	never	never	ADV
easat-267	162	10	experience	experience	VERB
easat-267	162	11	any	any	DET
easat-267	162	12	signs	sign	NOUN
easat-267	162	13	or	or	CCONJ
easat-267	162	14	symptoms	symptom	NOUN
easat-267	162	15	and	and	CCONJ
easat-267	162	16	are	be	AUX
easat-267	162	17	unaware	unaware	ADJ
easat-267	162	18	that	that	SCONJ
easat-267	162	19	they	they	PRON
easat-267	162	20	have	have	VERB
easat-267	162	21	the	the	DET
easat-267	162	22	condition	condition	NOUN
easat-267	162	23	.	.	PUNCT
easat-267	163	1	on	on	ADP
easat-267	163	2	the	the	DET
easat-267	163	3	other	other	ADJ
easat-267	163	4	hand	hand	NOUN
easat-267	163	5	,	,	PUNCT
easat-267	163	6	age	age	NOUN
easat-267	163	7	specific	specific	ADJ
easat-267	163	8	mortality	mortality	NOUN
easat-267	163	9	is	be	AUX
easat-267	163	10	high	high	ADJ
easat-267	163	11	,	,	PUNCT
easat-267	163	12	i.e.	i.e.	X
easat-267	163	13	,	,	PUNCT
easat-267	163	14	as	as	SCONJ
easat-267	163	15	the	the	DET
easat-267	163	16	age	age	NOUN
easat-267	163	17	advances	advance	VERB
easat-267	163	18	,	,	PUNCT
easat-267	163	19	the	the	DET
easat-267	163	20	number	number	NOUN
easat-267	163	21	of	of	ADP
easat-267	163	22	g6pd	g6pd	NOUN
easat-267	163	23	deficiency	deficiency	NOUN
easat-267	163	24	individuals	individual	NOUN
easat-267	163	25	go	go	VERB
easat-267	163	26	on	on	ADP
easat-267	163	27	decreasing	decrease	VERB
easat-267	163	28	in	in	ADP
easat-267	163	29	a	a	DET
easat-267	163	30	malaria	malaria	ADJ
easat-267	163	31	endemic	endemic	ADJ
easat-267	163	32	populations	population	NOUN
easat-267	163	33	,	,	PUNCT
easat-267	163	34	has	have	AUX
easat-267	163	35	been	be	AUX
easat-267	163	36	reported	report	VERB
easat-267	163	37	by	by	ADP
easat-267	163	38	some	some	DET
easat-267	163	39	investigators	investigator	NOUN
easat-267	163	40	[	[	X
easat-267	163	41	32	32	NUM
easat-267	163	42	]	]	PUNCT
easat-267	163	43	.	.	PUNCT
easat-267	164	1	the	the	DET
easat-267	164	2	g6pd	g6pd	NOUN
easat-267	164	3	enzyme	enzyme	NOUN
easat-267	164	4	deficiency	deficiency	NOUN
easat-267	164	5	is	be	AUX
easat-267	164	6	inherited	inherit	VERB
easat-267	164	7	as	as	ADP
easat-267	164	8	an	an	DET
easat-267	164	9	x	x	ADV
easat-267	164	10	-	-	ADJ
easat-267	164	11	linked	link	VERB
easat-267	164	12	recessive	recessive	ADJ
easat-267	164	13	pattern	pattern	NOUN
easat-267	164	14	.	.	PUNCT
easat-267	165	1	the	the	DET
easat-267	165	2	gene	gene	NOUN
easat-267	165	3	associated	associate	VERB
easat-267	165	4	with	with	ADP
easat-267	165	5	this	this	DET
easat-267	165	6	enzyme	enzyme	NOUN
easat-267	165	7	deficiency	deficiency	NOUN
easat-267	165	8	is	be	AUX
easat-267	165	9	located	locate	VERB
easat-267	165	10	on	on	ADP
easat-267	165	11	the	the	DET
easat-267	165	12	x	x	ADJ
easat-267	165	13	chromosome	chromosome	NOUN
easat-267	165	14	,	,	PUNCT
easat-267	165	15	which	which	PRON
easat-267	165	16	is	be	AUX
easat-267	165	17	one	one	NUM
easat-267	165	18	of	of	ADP
easat-267	165	19	the	the	DET
easat-267	165	20	two	two	NUM
easat-267	165	21	sex	sex	NOUN
easat-267	165	22	-	-	PUNCT
easat-267	165	23	chromosomes	chromosome	NOUN
easat-267	165	24	.	.	PUNCT
easat-267	166	1	in	in	ADP
easat-267	166	2	males	male	NOUN
easat-267	166	3	(	(	PUNCT
easat-267	166	4	who	who	PRON
easat-267	166	5	have	have	VERB
easat-267	166	6	only	only	ADV
easat-267	166	7	one	one	NUM
easat-267	166	8	x	x	NOUN
easat-267	166	9	chromosome	chromosome	NOUN
easat-267	166	10	,	,	PUNCT
easat-267	166	11	in	in	ADP
easat-267	166	12	hemizygous	hemizygous	ADJ
easat-267	166	13	condition	condition	NOUN
easat-267	166	14	)	)	PUNCT
easat-267	166	15	,	,	PUNCT
easat-267	166	16	one	one	NUM
easat-267	166	17	altered	alter	VERB
easat-267	166	18	copy	copy	NOUN
easat-267	166	19	of	of	ADP
easat-267	166	20	the	the	DET
easat-267	166	21	gene	gene	NOUN
easat-267	166	22	in	in	ADP
easat-267	166	23	each	each	DET
easat-267	166	24	cell	cell	NOUN
easat-267	166	25	is	be	AUX
easat-267	166	26	sufficient	sufficient	ADJ
easat-267	166	27	to	to	PART
easat-267	166	28	cause	cause	VERB
easat-267	166	29	the	the	DET
easat-267	166	30	deficiency	deficiency	NOUN
easat-267	166	31	.	.	PUNCT
easat-267	167	1	in	in	ADP
easat-267	167	2	females	female	NOUN
easat-267	167	3	(	(	PUNCT
easat-267	167	4	who	who	PRON
easat-267	167	5	have	have	VERB
easat-267	167	6	two	two	NUM
easat-267	167	7	x	x	NOUN
easat-267	167	8	chromosomes	chromosome	NOUN
easat-267	167	9	)	)	PUNCT
easat-267	167	10	,	,	PUNCT
easat-267	167	11	a	a	DET
easat-267	167	12	mutation	mutation	NOUN
easat-267	167	13	would	would	AUX
easat-267	167	14	have	have	VERB
easat-267	167	15	to	to	PART
easat-267	167	16	occur	occur	VERB
easat-267	167	17	in	in	ADP
easat-267	167	18	both	both	DET
easat-267	167	19	copies	copy	NOUN
easat-267	167	20	(	(	PUNCT
easat-267	167	21	alleles	allele	NOUN
easat-267	167	22	)	)	PUNCT
easat-267	167	23	of	of	ADP
easat-267	167	24	the	the	DET
easat-267	167	25	gene	gene	NOUN
easat-267	167	26	to	to	PART
easat-267	167	27	cause	cause	VERB
easat-267	167	28	the	the	DET
easat-267	167	29	disease	disease	NOUN
easat-267	167	30	.	.	PUNCT
easat-267	168	1	but	but	CCONJ
easat-267	168	2	,	,	PUNCT
easat-267	168	3	daughters	daughter	NOUN
easat-267	168	4	always	always	ADV
easat-267	168	5	get	get	VERB
easat-267	168	6	their	their	PRON
easat-267	168	7	x	x	NOUN
easat-267	168	8	chromosomes	chromosome	NOUN
easat-267	168	9	from	from	ADP
easat-267	168	10	parents	parent	NOUN
easat-267	168	11	,	,	PUNCT
easat-267	168	12	one	one	NUM
easat-267	168	13	each	each	PRON
easat-267	168	14	from	from	ADP
easat-267	168	15	father	father	NOUN
easat-267	168	16	and	and	CCONJ
easat-267	168	17	mother	mother	NOUN
easat-267	168	18	.	.	PUNCT
easat-267	169	1	therefore	therefore	ADV
easat-267	169	2	,	,	PUNCT
easat-267	169	3	they	they	PRON
easat-267	169	4	may	may	AUX
easat-267	169	5	be	be	AUX
easat-267	169	6	heterozygote	heterozygote	NOUN
easat-267	169	7	,	,	PUNCT
easat-267	169	8	if	if	SCONJ
easat-267	169	9	father	father	PROPN
easat-267	169	10	is	be	AUX
easat-267	169	11	affected	affect	VERB
easat-267	169	12	and	and	CCONJ
easat-267	169	13	mother	mother	NOUN
easat-267	169	14	is	be	AUX
easat-267	169	15	normal	normal	ADJ
easat-267	169	16	.	.	PUNCT
easat-267	170	1	similarly	similarly	ADV
easat-267	170	2	,	,	PUNCT
easat-267	170	3	they	they	PRON
easat-267	170	4	may	may	AUX
easat-267	170	5	also	also	ADV
easat-267	170	6	be	be	AUX
easat-267	170	7	heterozygote	heterozygote	NOUN
easat-267	170	8	,	,	PUNCT
easat-267	170	9	if	if	SCONJ
easat-267	170	10	one	one	NUM
easat-267	170	11	of	of	ADP
easat-267	170	12	the	the	DET
easat-267	170	13	x	x	NOUN
easat-267	170	14	chromosomes	chromosome	NOUN
easat-267	170	15	is	be	AUX
easat-267	170	16	carrier	carrier	NOUN
easat-267	170	17	or	or	CCONJ
easat-267	170	18	trait	trait	NOUN
easat-267	170	19	for	for	ADP
easat-267	170	20	g6pd	g6pd	NOUN
easat-267	170	21	deficiency	deficiency	NOUN
easat-267	170	22	.	.	PUNCT
easat-267	171	1	further	far	ADV
easat-267	171	2	it	it	PRON
easat-267	171	3	all	all	PRON
easat-267	171	4	depends	depend	VERB
easat-267	171	5	on	on	ADP
easat-267	171	6	the	the	DET
easat-267	171	7	x	x	PUNCT
easat-267	171	8	chromosome	chromosome	NOUN
easat-267	171	9	,	,	PUNCT
easat-267	171	10	either	either	CCONJ
easat-267	171	11	inherited	inherit	VERB
easat-267	171	12	from	from	ADP
easat-267	171	13	affected	affect	VERB
easat-267	171	14	father	father	NOUN
easat-267	171	15	or	or	CCONJ
easat-267	171	16	carrier	carrier	NOUN
easat-267	171	17	mother	mother	NOUN
easat-267	171	18	,	,	PUNCT
easat-267	171	19	and	and	CCONJ
easat-267	171	20	also	also	ADV
easat-267	171	21	on	on	ADP
easat-267	171	22	the	the	DET
easat-267	171	23	activation	activation	NOUN
easat-267	171	24	of	of	ADP
easat-267	171	25	one	one	NUM
easat-267	171	26	(	(	PUNCT
easat-267	171	27	normal	normal	ADJ
easat-267	171	28	or	or	CCONJ
easat-267	171	29	abnormal	abnormal	ADJ
easat-267	171	30	)	)	PUNCT
easat-267	171	31	out	out	ADP
easat-267	171	32	of	of	ADP
easat-267	171	33	the	the	DET
easat-267	171	34	mother	mother	NOUN
easat-267	171	35	’s	’s	PART
easat-267	171	36	two	two	NUM
easat-267	171	37	x	x	NOUN
easat-267	171	38	chromosomes	chromosome	NOUN
easat-267	171	39	according	accord	VERB
easat-267	171	40	to	to	ADP
easat-267	171	41	the	the	DET
easat-267	171	42	lyon	lyon	NOUN
easat-267	171	43	’s	’s	PART
easat-267	171	44	hypothesis	hypothesis	NOUN
easat-267	171	45	[	[	X
easat-267	171	46	9,10	9,10	X
easat-267	171	47	]	]	X
easat-267	171	48	.	.	PUNCT
easat-267	172	1	thus	thus	ADV
easat-267	172	2	,	,	PUNCT
easat-267	172	3	g6pd	g6pd	NOUN
easat-267	172	4	deficiency	deficiency	NOUN
easat-267	172	5	would	would	AUX
easat-267	172	6	have	have	VERB
easat-267	172	7	to	to	PART
easat-267	172	8	occur	occur	VERB
easat-267	172	9	in	in	ADP
easat-267	172	10	both	both	PRON
easat-267	172	11	x	x	NOUN
easat-267	172	12	chromosomes	chromosome	NOUN
easat-267	172	13	(	(	PUNCT
easat-267	172	14	counter	counter	NOUN
easat-267	172	15	parts	part	NOUN
easat-267	172	16	)	)	PUNCT
easat-267	172	17	of	of	ADP
easat-267	172	18	females	female	NOUN
easat-267	172	19	(	(	PUNCT
easat-267	172	20	from	from	ADP
easat-267	172	21	father	father	PROPN
easat-267	172	22	as	as	ADV
easat-267	172	23	well	well	ADV
easat-267	172	24	as	as	ADP
easat-267	172	25	from	from	ADP
easat-267	172	26	mother	mother	NOUN
easat-267	172	27	)	)	PUNCT
easat-267	172	28	to	to	PART
easat-267	172	29	fully	fully	ADV
easat-267	172	30	express	express	VERB
easat-267	172	31	the	the	DET
easat-267	172	32	defective	defective	ADJ
easat-267	172	33	gene	gene	NOUN
easat-267	172	34	(	(	PUNCT
easat-267	172	35	in	in	ADP
easat-267	172	36	homozygous	homozygous	ADJ
easat-267	172	37	state	state	NOUN
easat-267	172	38	)	)	PUNCT
easat-267	172	39	.	.	PUNCT
easat-267	173	1	males	male	NOUN
easat-267	173	2	are	be	AUX
easat-267	173	3	affected	affect	VERB
easat-267	173	4	by	by	ADP
easat-267	173	5	x	x	VERB
easat-267	173	6	-	-	VERB
easat-267	173	7	linked	link	VERB
easat-267	173	8	recessive	recessive	ADJ
easat-267	173	9	disorders	disorder	NOUN
easat-267	173	10	much	much	ADV
easat-267	173	11	more	more	ADV
easat-267	173	12	frequently	frequently	ADV
easat-267	173	13	than	than	ADP
easat-267	173	14	the	the	DET
easat-267	173	15	females	female	NOUN
easat-267	173	16	(	(	PUNCT
easat-267	173	17	tables	table	NOUN
easat-267	173	18	1	1	NUM
easat-267	173	19	-	-	SYM
easat-267	173	20	4	4	NUM
easat-267	173	21	)	)	PUNCT
easat-267	173	22	.	.	PUNCT
easat-267	174	1	a	a	DET
easat-267	174	2	characteristic	characteristic	NOUN
easat-267	174	3	of	of	ADP
easat-267	174	4	x	x	ADJ
easat-267	174	5	-	-	VERB
easat-267	174	6	linked	link	VERB
easat-267	174	7	inheritance	inheritance	NOUN
easat-267	174	8	is	be	AUX
easat-267	174	9	that	that	SCONJ
easat-267	174	10	fathers	father	NOUN
easat-267	174	11	can	can	AUX
easat-267	174	12	not	not	PART
easat-267	174	13	pass	pass	VERB
easat-267	174	14	x	x	ADJ
easat-267	174	15	-	-	ADJ
easat-267	174	16	linked	link	VERB
easat-267	174	17	traits	trait	NOUN
easat-267	174	18	to	to	ADP
easat-267	174	19	their	their	PRON
easat-267	174	20	sons	son	NOUN
easat-267	174	21	[	[	X
easat-267	174	22	47	47	NUM
easat-267	174	23	]	]	PUNCT
easat-267	174	24	.	.	PUNCT
easat-267	175	1	in	in	ADP
easat-267	175	2	contrast	contrast	NOUN
easat-267	175	3	to	to	ADP
easat-267	175	4	the	the	DET
easat-267	175	5	findings	finding	NOUN
easat-267	175	6	by	by	ADP
easat-267	175	7	ruwende	ruwende	NOUN
easat-267	175	8	et	et	PROPN
easat-267	175	9	al	al	PROPN
easat-267	175	10	.	.	PUNCT
easat-267	176	1	a	a	DET
easat-267	176	2	later	later	ADJ
easat-267	176	3	study	study	NOUN
easat-267	176	4	showed	show	VERB
easat-267	176	5	that	that	SCONJ
easat-267	176	6	a	a	DET
easat-267	176	7	form	form	NOUN
easat-267	176	8	of	of	ADP
easat-267	176	9	g6pd	g6pd	NOUN
easat-267	176	10	deficiency	deficiency	NOUN
easat-267	176	11	confers	confer	NOUN
easat-267	176	12	protection	protection	NOUN
easat-267	176	13	against	against	ADP
easat-267	176	14	severe	severe	ADJ
easat-267	176	15	malaria	malaria	NOUN
easat-267	176	16	in	in	ADP
easat-267	176	17	its	its	PRON
easat-267	176	18	uniform	uniform	ADJ
easat-267	176	19	state	state	NOUN
easat-267	176	20	(	(	PUNCT
easat-267	176	21	hemizygous	hemizygous	ADJ
easat-267	176	22	males	male	NOUN
easat-267	176	23	and	and	CCONJ
easat-267	176	24	homozygous	homozygous	ADJ
easat-267	176	25	females	female	NOUN
easat-267	176	26	)	)	PUNCT
easat-267	176	27	but	but	CCONJ
easat-267	176	28	not	not	PART
easat-267	176	29	in	in	ADP
easat-267	176	30	its	its	PRON
easat-267	176	31	mosaic	mosaic	ADJ
easat-267	176	32	state	state	NOUN
easat-267	176	33	,	,	PUNCT
easat-267	176	34	i.e.	i.e.	X
easat-267	176	35	heterozygous	heterozygous	ADJ
easat-267	176	36	females	female	NOUN
easat-267	176	37	[	[	X
easat-267	176	38	48	48	NUM
easat-267	176	39	]	]	PUNCT
easat-267	176	40	.	.	PUNCT
easat-267	177	1	this	this	DET
easat-267	177	2	finding	finding	NOUN
easat-267	177	3	is	be	AUX
easat-267	177	4	consistent	consistent	ADJ
easat-267	177	5	with	with	ADP
easat-267	177	6	those	those	DET
easat-267	177	7	protection	protection	NOUN
easat-267	177	8	mechanisms	mechanism	NOUN
easat-267	177	9	involving	involve	VERB
easat-267	177	10	either	either	CCONJ
easat-267	177	11	enhanced	enhanced	ADJ
easat-267	177	12	phagocytosis	phagocytosis	NOUN
easat-267	177	13	or	or	CCONJ
easat-267	177	14	the	the	DET
easat-267	177	15	effects	effect	NOUN
easat-267	177	16	on	on	ADP
easat-267	177	17	pathogenic	pathogenic	ADJ
easat-267	177	18	consequences	consequence	NOUN
easat-267	177	19	in	in	ADP
easat-267	177	20	the	the	DET
easat-267	177	21	microcirculation	microcirculation	NOUN
easat-267	177	22	of	of	ADP
easat-267	177	23	parasitized	parasitize	VERB
easat-267	177	24	erythrocytes	erythrocyte	NOUN
easat-267	177	25	,	,	PUNCT
easat-267	177	26	since	since	SCONJ
easat-267	177	27	both	both	PRON
easat-267	177	28	are	be	AUX
easat-267	177	29	expected	expect	VERB
easat-267	177	30	to	to	PART
easat-267	177	31	operate	operate	VERB
easat-267	177	32	preferentially	preferentially	ADV
easat-267	177	33	on	on	ADP
easat-267	177	34	uniformly	uniformly	ADV
easat-267	177	35	deficient	deficient	ADJ
easat-267	177	36	erythrocytes	erythrocyte	NOUN
easat-267	178	1	[	[	X
easat-267	178	2	26	26	NUM
easat-267	178	3	]	]	PUNCT
easat-267	178	4	.	.	PUNCT
easat-267	179	1	1.9	1.9	NUM
easat-267	179	2	.	.	PUNCT
easat-267	179	3	red	red	ADJ
easat-267	179	4	cell	cell	NOUN
easat-267	179	5	genetic	genetic	ADJ
easat-267	179	6	variants	variant	NOUN
easat-267	179	7	and	and	CCONJ
easat-267	179	8	natural	natural	ADJ
easat-267	179	9	selection	selection	NOUN
easat-267	179	10	against	against	ADP
easat-267	179	11	malaria	malaria	NOUN
easat-267	179	12	high	high	ADJ
easat-267	179	13	frequency	frequency	NOUN
easat-267	179	14	distribution	distribution	NOUN
easat-267	179	15	of	of	ADP
easat-267	179	16	inherited	inherit	VERB
easat-267	179	17	hemoglobin	hemoglobin	NOUN
easat-267	179	18	disorders	disorder	NOUN
easat-267	179	19	including	include	VERB
easat-267	179	20	thalassemias	thalassemia	NOUN
easat-267	179	21	,	,	PUNCT
easat-267	179	22	and	and	CCONJ
easat-267	179	23	red	red	ADJ
easat-267	179	24	cell	cell	NOUN
easat-267	179	25	g6pd	g6pd	NOUN
easat-267	179	26	enzyme	enzyme	NOUN
easat-267	179	27	deficiency	deficiency	NOUN
easat-267	179	28	,	,	PUNCT
easat-267	179	29	which	which	PRON
easat-267	179	30	have	have	AUX
easat-267	179	31	probably	probably	ADV
easat-267	179	32	evolved	evolve	VERB
easat-267	179	33	simultaneously	simultaneously	ADV
easat-267	179	34	in	in	ADP
easat-267	179	35	relation	relation	NOUN
easat-267	179	36	to	to	PART
easat-267	179	37	malaria	malaria	VERB
easat-267	179	38	in	in	ADP
easat-267	179	39	different	different	ADJ
easat-267	179	40	vulnerable	vulnerable	ADJ
easat-267	179	41	and	and	CCONJ
easat-267	179	42	malaria	malaria	ADJ
easat-267	179	43	endemic	endemic	ADJ
easat-267	179	44	populations	population	NOUN
easat-267	179	45	,	,	PUNCT
easat-267	179	46	and	and	CCONJ
easat-267	179	47	high	high	ADJ
easat-267	179	48	mortality	mortality	NOUN
easat-267	179	49	caused	cause	VERB
easat-267	179	50	by	by	ADP
easat-267	179	51	plasmodium	plasmodium	NOUN
easat-267	179	52	falciparum	falciparum	ADJ
easat-267	179	53	malaria	malaria	NOUN
easat-267	179	54	in	in	ADP
easat-267	179	55	different	different	ADJ
easat-267	179	56	tropical	tropical	ADJ
easat-267	179	57	and	and	CCONJ
easat-267	179	58	subtropical	subtropical	ADJ
easat-267	179	59	parts	part	NOUN
easat-267	179	60	of	of	ADP
easat-267	179	61	the	the	DET
easat-267	179	62	world	world	NOUN
easat-267	179	63	confirm	confirm	VERB
easat-267	179	64	that	that	SCONJ
easat-267	179	65	the	the	DET
easat-267	179	66	natural	natural	ADJ
easat-267	179	67	selection	selection	NOUN
easat-267	179	68	is	be	AUX
easat-267	179	69	certainly	certainly	ADV
easat-267	179	70	operating	operate	VERB
easat-267	179	71	against	against	ADP
easat-267	179	72	malaria	malaria	NOUN
easat-267	179	73	in	in	ADP
easat-267	179	74	one	one	NUM
easat-267	179	75	way	way	NOUN
easat-267	179	76	or	or	CCONJ
easat-267	179	77	another	another	PRON
easat-267	179	78	;	;	PUNCT
easat-267	179	79	and	and	CCONJ
easat-267	179	80	human	human	ADJ
easat-267	179	81	population	population	NOUN
easat-267	179	82	genetics	genetic	NOUN
easat-267	179	83	play	play	VERB
easat-267	179	84	a	a	DET
easat-267	179	85	major	major	ADJ
easat-267	179	86	role	role	NOUN
easat-267	179	87	in	in	ADP
easat-267	179	88	this	this	DET
easat-267	179	89	process	process	NOUN
easat-267	179	90	of	of	ADP
easat-267	179	91	co	co	NOUN
easat-267	179	92	-	-	NOUN
easat-267	179	93	evolution	evolution	NOUN
easat-267	179	94	of	of	ADP
easat-267	179	95	human	human	ADJ
easat-267	179	96	-	-	PUNCT
easat-267	179	97	beings	being	NOUN
easat-267	179	98	and	and	CCONJ
easat-267	179	99	malaria	malaria	NOUN
easat-267	179	100	.	.	PUNCT
easat-267	180	1	the	the	DET
easat-267	180	2	people	people	NOUN
easat-267	180	3	who	who	PRON
easat-267	180	4	have	have	VERB
easat-267	180	5	a	a	DET
easat-267	180	6	g6pd	g6pd	NOUN
easat-267	180	7	deficiency	deficiency	NOUN
easat-267	180	8	mutation	mutation	NOUN
easat-267	180	9	may	may	AUX
easat-267	180	10	be	be	AUX
easat-267	180	11	partially	partially	ADV
easat-267	180	12	protected	protect	VERB
easat-267	180	13	against	against	ADP
easat-267	180	14	plasmodium	plasmodium	NOUN
easat-267	180	15	falciparum	falciparum	NOUN
easat-267	180	16	malaria	malaria	NOUN
easat-267	180	17	.	.	PUNCT
easat-267	181	1	the	the	DET
easat-267	181	2	deficiency	deficiency	NOUN
easat-267	181	3	of	of	ADP
easat-267	181	4	g6pd	g6pd	NOUN
easat-267	181	5	enzyme	enzyme	NOUN
easat-267	181	6	or	or	CCONJ
easat-267	181	7	a	a	DET
easat-267	181	8	reduction	reduction	NOUN
easat-267	181	9	in	in	ADP
easat-267	181	10	the	the	DET
easat-267	181	11	amount	amount	NOUN
easat-267	181	12	of	of	ADP
easat-267	181	13	functional	functional	ADJ
easat-267	181	14	g6pd	g6pd	NOUN
easat-267	181	15	appears	appear	VERB
easat-267	181	16	to	to	PART
easat-267	181	17	make	make	VERB
easat-267	181	18	it	it	PRON
easat-267	181	19	more	more	ADV
easat-267	181	20	difficult	difficult	ADJ
easat-267	181	21	for	for	SCONJ
easat-267	181	22	the	the	DET
easat-267	181	23	malaria	malaria	NOUN
easat-267	181	24	parasite	parasite	NOUN
easat-267	181	25	to	to	PART
easat-267	181	26	invade	invade	VERB
easat-267	181	27	red	red	ADJ
easat-267	181	28	blood	blood	NOUN
easat-267	181	29	cells	cell	NOUN
easat-267	181	30	,	,	PUNCT
easat-267	181	31	inhibits	inhibit	VERB
easat-267	181	32	its	its	PRON
easat-267	181	33	growth	growth	NOUN
easat-267	181	34	,	,	PUNCT
easat-267	181	35	and	and	CCONJ
easat-267	181	36	phagocytises	phagocytise	NOUN
easat-267	181	37	rapidly	rapidly	ADV
easat-267	182	1	[	[	X
easat-267	182	2	49	49	NUM
easat-267	182	3	]	]	PUNCT
easat-267	182	4	.	.	PUNCT
easat-267	183	1	g6pd	g6pd	NOUN
easat-267	183	2	deficiency	deficiency	NOUN
easat-267	183	3	occurs	occur	VERB
easat-267	183	4	most	most	ADV
easat-267	183	5	frequently	frequently	ADV
easat-267	183	6	in	in	ADP
easat-267	183	7	areas	area	NOUN
easat-267	183	8	of	of	ADP
easat-267	183	9	the	the	DET
easat-267	183	10	world	world	NOUN
easat-267	183	11	where	where	SCONJ
easat-267	183	12	malaria	malaria	NOUN
easat-267	183	13	is	be	AUX
easat-267	183	14	common	common	ADJ
easat-267	183	15	.	.	PUNCT
easat-267	184	1	moreover	moreover	ADV
easat-267	184	2	,	,	PUNCT
easat-267	184	3	disequilibrium	disequilibrium	NOUN
easat-267	184	4	of	of	ADP
easat-267	184	5	genetic	genetic	ADJ
easat-267	184	6	markers	marker	NOUN
easat-267	184	7	such	such	ADJ
easat-267	184	8	as	as	ADP
easat-267	184	9	various	various	ADJ
easat-267	184	10	variants	variant	NOUN
easat-267	184	11	of	of	ADP
easat-267	184	12	hemoglobin	hemoglobin	NOUN
easat-267	184	13	and	and	CCONJ
easat-267	184	14	high	high	ADJ
easat-267	184	15	occurrence	occurrence	NOUN
easat-267	184	16	of	of	ADP
easat-267	184	17	g6pd	g6pd	NOUN
easat-267	184	18	deficiency	deficiency	NOUN
easat-267	184	19	is	be	AUX
easat-267	184	20	reflected	reflect	VERB
easat-267	184	21	as	as	ADP
easat-267	184	22	the	the	DET
easat-267	184	23	natural	natural	ADJ
easat-267	184	24	selection	selection	NOUN
easat-267	184	25	mechanism	mechanism	NOUN
easat-267	184	26	for	for	ADP
easat-267	184	27	protection	protection	NOUN
easat-267	184	28	against	against	ADP
easat-267	184	29	malaria	malaria	NOUN
easat-267	184	30	[	[	X
easat-267	184	31	1,2,11,27,31	1,2,11,27,31	NOUN
easat-267	184	32	]	]	PUNCT
easat-267	184	33	.	.	PUNCT
easat-267	185	1	natural	natural	ADJ
easat-267	185	2	selection	selection	NOUN
easat-267	185	3	can	can	AUX
easat-267	185	4	maintain	maintain	VERB
easat-267	185	5	deleterious	deleterious	ADJ
easat-267	185	6	alleles	allele	NOUN
easat-267	185	7	in	in	ADP
easat-267	185	8	the	the	DET
easat-267	185	9	population	population	NOUN
easat-267	185	10	if	if	SCONJ
easat-267	185	11	there	there	PRON
easat-267	185	12	is	be	VERB
easat-267	185	13	a	a	DET
easat-267	185	14	heterozygote	heterozygote	NOUN
easat-267	185	15	advantage	advantage	NOUN
easat-267	185	16	(	(	PUNCT
easat-267	185	17	positive	positive	ADJ
easat-267	185	18	selection	selection	NOUN
easat-267	185	19	)	)	PUNCT
easat-267	185	20	as	as	ADP
easat-267	185	21	in	in	ADP
easat-267	185	22	the	the	DET
easat-267	185	23	case	case	NOUN
easat-267	185	24	of	of	ADP
easat-267	185	25	sickle	sickle	NOUN
easat-267	185	26	cell	cell	NOUN
easat-267	185	27	trait	trait	NOUN
easat-267	185	28	(	(	PUNCT
easat-267	185	29	hb	hb	X
easat-267	185	30	as	as	ADP
easat-267	185	31	)	)	PUNCT
easat-267	185	32	.	.	PUNCT
easat-267	186	1	when	when	SCONJ
easat-267	186	2	the	the	DET
easat-267	186	3	frequency	frequency	NOUN
easat-267	186	4	of	of	ADP
easat-267	186	5	sickle	sickle	PROPN
easat-267	186	6	cell	cell	NOUN
easat-267	186	7	allele	allele	NOUN
easat-267	186	8	decreases	decrease	VERB
easat-267	186	9	in	in	ADP
easat-267	186	10	malaria	malaria	ADJ
easat-267	186	11	endemic	endemic	ADJ
easat-267	186	12	cross	cross	NOUN
easat-267	186	13	-	-	NOUN
easat-267	186	14	section	section	NOUN
easat-267	186	15	of	of	ADP
easat-267	186	16	the	the	DET
easat-267	186	17	tribal	tribal	ADJ
easat-267	186	18	population	population	NOUN
easat-267	186	19	in	in	ADP
easat-267	186	20	india	india	PROPN
easat-267	186	21	,	,	PUNCT
easat-267	186	22	the	the	DET
easat-267	186	23	frequency	frequency	NOUN
easat-267	186	24	of	of	ADP
easat-267	186	25	g6pd	g6pd	NOUN
easat-267	186	26	enzyme	enzyme	NOUN
easat-267	186	27	deficiency	deficiency	NOUN
easat-267	186	28	allele	allele	NOUN
easat-267	186	29	increases	increase	NOUN
easat-267	186	30	and	and	CCONJ
easat-267	186	31	vice	vice	NOUN
easat-267	186	32	versa	versa	ADV
easat-267	187	1	[	[	X
easat-267	187	2	1,2	1,2	NUM
easat-267	187	3	]	]	PUNCT
easat-267	187	4	.	.	PUNCT
easat-267	188	1	this	this	DET
easat-267	188	2	trend	trend	NOUN
easat-267	188	3	for	for	ADP
easat-267	188	4	an	an	DET
easat-267	188	5	inverse	inverse	NOUN
easat-267	188	6	relationship	relationship	NOUN
easat-267	188	7	between	between	ADP
easat-267	188	8	sickle	sickle	NOUN
easat-267	188	9	cell	cell	NOUN
easat-267	188	10	disorders	disorder	NOUN
easat-267	188	11	and	and	CCONJ
easat-267	188	12	g6pd	g6pd	NOUN
easat-267	188	13	deficiency	deficiency	NOUN
easat-267	188	14	due	due	ADP
easat-267	188	15	to	to	ADP
easat-267	188	16	disequilibrium	disequilibrium	NOUN
easat-267	188	17	in	in	ADP
easat-267	188	18	major	major	ADJ
easat-267	188	19	scheduled	schedule	VERB
easat-267	188	20	caste	caste	NOUN
easat-267	188	21	and	and	CCONJ
easat-267	188	22	tribal	tribal	ADJ
easat-267	188	23	communities	community	NOUN
easat-267	188	24	of	of	ADP
easat-267	188	25	central	central	ADJ
easat-267	188	26	-	-	PUNCT
easat-267	188	27	eastern	eastern	ADJ
easat-267	188	28	india	india	PROPN
easat-267	188	29	,	,	PUNCT
easat-267	188	30	is	be	AUX
easat-267	188	31	fascinating	fascinate	VERB
easat-267	189	1	one	one	NUM
easat-267	189	2	[	[	X
easat-267	189	3	1,2	1,2	NUM
easat-267	189	4	]	]	PUNCT
easat-267	189	5	.	.	PUNCT
easat-267	190	1	this	this	DET
easat-267	190	2	medical	medical	ADJ
easat-267	190	3	aspect	aspect	NOUN
easat-267	190	4	is	be	AUX
easat-267	190	5	important	important	ADJ
easat-267	190	6	from	from	ADP
easat-267	190	7	an	an	DET
easat-267	190	8	evolutionary	evolutionary	ADJ
easat-267	190	9	biological	biological	ADJ
easat-267	190	10	background	background	NOUN
easat-267	190	11	and	and	CCONJ
easat-267	190	12	could	could	AUX
easat-267	190	13	be	be	AUX
easat-267	190	14	an	an	DET
easat-267	190	15	excellent	excellent	ADJ
easat-267	190	16	starting	starting	NOUN
easat-267	190	17	point	point	NOUN
easat-267	190	18	for	for	ADP
easat-267	190	19	molecular	molecular	ADJ
easat-267	190	20	analyses	analysis	NOUN
easat-267	190	21	to	to	PART
easat-267	190	22	determine	determine	VERB
easat-267	190	23	the	the	DET
easat-267	190	24	signature	signature	NOUN
easat-267	190	25	of	of	ADP
easat-267	190	26	natural	natural	ADJ
easat-267	190	27	selection	selection	NOUN
easat-267	190	28	in	in	ADP
easat-267	190	29	the	the	DET
easat-267	190	30	genomic	genomic	ADJ
easat-267	190	31	regions	region	NOUN
easat-267	190	32	of	of	ADP
easat-267	190	33	the	the	DET
easat-267	190	34	β	β	NOUN
easat-267	190	35	-	-	PUNCT
easat-267	190	36	globin	globin	ADJ
easat-267	190	37	and	and	CCONJ
easat-267	190	38	g6pd	g6pd	NOUN
easat-267	190	39	genes	gene	NOUN
easat-267	190	40	.	.	PUNCT
easat-267	191	1	this	this	PRON
easat-267	191	2	may	may	AUX
easat-267	191	3	further	far	ADV
easat-267	191	4	provide	provide	VERB
easat-267	191	5	a	a	DET
easat-267	191	6	mechanism	mechanism	NOUN
easat-267	191	7	for	for	ADP
easat-267	191	8	how	how	SCONJ
easat-267	191	9	natural	natural	ADJ
easat-267	191	10	selection	selection	NOUN
easat-267	191	11	operates	operate	VERB
easat-267	191	12	against	against	ADP
easat-267	191	13	malaria	malaria	NOUN
easat-267	191	14	when	when	SCONJ
easat-267	191	15	two	two	NUM
easat-267	191	16	mutations	mutation	NOUN
easat-267	191	17	occur	occur	VERB
easat-267	191	18	in	in	ADP
easat-267	191	19	the	the	DET
easat-267	191	20	same	same	ADJ
easat-267	191	21	geographical	geographical	ADJ
easat-267	191	22	region	region	NOUN
easat-267	192	1	[	[	X
easat-267	192	2	2	2	NUM
easat-267	192	3	]	]	PUNCT
easat-267	192	4	.	.	PUNCT
easat-267	193	1	similarly	similarly	ADV
easat-267	193	2	,	,	PUNCT
easat-267	193	3	further	further	ADJ
easat-267	193	4	work	work	NOUN
easat-267	193	5	on	on	ADP
easat-267	193	6	the	the	DET
easat-267	193	7	remarkable	remarkable	ADJ
easat-267	193	8	epistatic	epistatic	ADJ
easat-267	193	9	interactions	interaction	NOUN
easat-267	193	10	between	between	ADP
easat-267	193	11	various	various	ADJ
easat-267	193	12	malaria	malaria	NOUN
easat-267	193	13	-	-	PUNCT
easat-267	193	14	protective	protective	ADJ
easat-267	193	15	polymorphisms	polymorphism	NOUN
easat-267	193	16	could	could	AUX
easat-267	193	17	provide	provide	VERB
easat-267	193	18	invaluable	invaluable	ADJ
easat-267	193	19	information	information	NOUN
easat-267	193	20	about	about	ADP
easat-267	193	21	the	the	DET
easat-267	193	22	mechanisms	mechanism	NOUN
easat-267	193	23	for	for	ADP
easat-267	193	24	the	the	DET
easat-267	193	25	distribution	distribution	NOUN
easat-267	193	26	of	of	ADP
easat-267	193	27	the	the	DET
easat-267	193	28	different	different	ADJ
easat-267	193	29	forms	form	NOUN
easat-267	193	30	of	of	ADP
easat-267	193	31	inherited	inherit	VERB
easat-267	193	32	hemoglobin	hemoglobin	NOUN
easat-267	193	33	disorders	disorder	NOUN
easat-267	193	34	particularly	particularly	ADV
easat-267	193	35	in	in	ADP
easat-267	193	36	high	high	ADJ
easat-267	193	37	-	-	PUNCT
easat-267	193	38	frequency	frequency	NOUN
easat-267	193	39	populations	population	NOUN
easat-267	193	40	(	(	PUNCT
easat-267	193	41	tables	table	NOUN
easat-267	193	42	1	1	NUM
easat-267	193	43	-	-	SYM
easat-267	193	44	4	4	NUM
easat-267	193	45	)	)	PUNCT
easat-267	193	46	.	.	PUNCT
easat-267	194	1	further	further	ADJ
easat-267	194	2	natural	natural	ADJ
easat-267	194	3	selection	selection	NOUN
easat-267	194	4	had	have	AUX
easat-267	194	5	played	play	VERB
easat-267	194	6	a	a	DET
easat-267	194	7	major	major	ADJ
easat-267	194	8	role	role	NOUN
easat-267	194	9	initially	initially	ADV
easat-267	194	10	in	in	ADP
easat-267	194	11	favor	favor	NOUN
easat-267	194	12	of	of	ADP
easat-267	194	13	sickle	sickle	NOUN
easat-267	194	14	cell	cell	NOUN
easat-267	194	15	,	,	PUNCT
easat-267	194	16	β	β	X
easat-267	194	17	-thalassemia	-thalassemia	NOUN
easat-267	194	18	and	and	CCONJ
easat-267	194	19	g6pd	g6pd	NOUN
easat-267	194	20	mutations	mutation	NOUN
easat-267	194	21	so	so	SCONJ
easat-267	194	22	that	that	SCONJ
easat-267	194	23	they	they	PRON
easat-267	194	24	have	have	AUX
easat-267	194	25	probably	probably	ADV
easat-267	194	26	evolved	evolve	VERB
easat-267	194	27	as	as	ADP
easat-267	194	28	a	a	DET
easat-267	194	29	protective	protective	ADJ
easat-267	194	30	mechanism	mechanism	NOUN
easat-267	194	31	against	against	ADP
easat-267	194	32	the	the	DET
easat-267	194	33	lethal	lethal	ADJ
easat-267	194	34	effects	effect	NOUN
easat-267	194	35	of	of	ADP
easat-267	194	36	malaria	malaria	NOUN
easat-267	194	37	.	.	PUNCT
easat-267	195	1	since	since	SCONJ
easat-267	195	2	the	the	DET
easat-267	195	3	selection	selection	NOUN
easat-267	195	4	favors	favor	VERB
easat-267	195	5	the	the	DET
easat-267	195	6	mutation	mutation	NOUN
easat-267	195	7	with	with	ADP
easat-267	195	8	least	least	ADJ
easat-267	195	9	cost	cost	VERB
easat-267	195	10	to	to	ADP
easat-267	195	11	the	the	DET
easat-267	195	12	population	population	NOUN
easat-267	195	13	,	,	PUNCT
easat-267	195	14	as	as	SCONJ
easat-267	195	15	the	the	DET
easat-267	195	16	clinical	clinical	ADJ
easat-267	195	17	50	50	NUM
easat-267	195	18	edelweiss	edelweiss	PROPN
easat-267	195	19	applied	apply	VERB
easat-267	195	20	science	science	NOUN
easat-267	195	21	and	and	CCONJ
easat-267	195	22	technology	technology	NOUN
easat-267	195	23	issn	issn	PROPN
easat-267	195	24	:	:	PUNCT
easat-267	195	25	2576	2576	NUM
easat-267	195	26	-	-	SYM
easat-267	195	27	8484	8484	NUM
easat-267	195	28	vol	vol	NOUN
easat-267	195	29	.	.	PROPN
easat-267	196	1	3	3	NUM
easat-267	196	2	,	,	PUNCT
easat-267	196	3	no	no	INTJ
easat-267	196	4	.	.	NOUN
easat-267	196	5	1	1	NUM
easat-267	196	6	:	:	SYM
easat-267	196	7	44	44	NUM
easat-267	196	8	-	-	SYM
easat-267	196	9	52	52	NUM
easat-267	196	10	,	,	PUNCT
easat-267	196	11	2019	2019	NUM
easat-267	196	12	doi	doi	NOUN
easat-267	196	13	:	:	PUNCT
easat-267	196	14	10.33805/2576	10.33805/2576	NUM
easat-267	196	15	-	-	SYM
easat-267	196	16	8484.167	8484.167	NUM
easat-267	196	17	©	©	PROPN
easat-267	196	18	2019	2019	NUM
easat-267	196	19	by	by	ADP
easat-267	196	20	the	the	DET
easat-267	196	21	author	author	NOUN
easat-267	196	22	manifestations	manifestation	NOUN
easat-267	196	23	of	of	ADP
easat-267	196	24	g6pd	g6pd	NOUN
easat-267	196	25	deficiency	deficiency	NOUN
easat-267	196	26	are	be	AUX
easat-267	196	27	mild	mild	ADJ
easat-267	196	28	and	and	CCONJ
easat-267	196	29	do	do	AUX
easat-267	196	30	not	not	PART
easat-267	196	31	result	result	VERB
easat-267	196	32	in	in	ADP
easat-267	196	33	a	a	DET
easat-267	196	34	complete	complete	ADJ
easat-267	196	35	loss	loss	NOUN
easat-267	196	36	of	of	ADP
easat-267	196	37	enzyme	enzyme	NOUN
easat-267	196	38	activity	activity	NOUN
easat-267	196	39	against	against	ADP
easat-267	196	40	the	the	DET
easat-267	196	41	sickle	sickle	NOUN
easat-267	196	42	cell	cell	NOUN
easat-267	196	43	disease	disease	NOUN
easat-267	196	44	with	with	ADP
easat-267	196	45	high	high	ADJ
easat-267	196	46	morbidity	morbidity	NOUN
easat-267	196	47	and	and	CCONJ
easat-267	196	48	mortality	mortality	NOUN
easat-267	196	49	in	in	ADP
easat-267	196	50	the	the	DET
easat-267	196	51	region	region	NOUN
easat-267	196	52	,	,	PUNCT
easat-267	196	53	and	and	CCONJ
easat-267	196	54	predominant	predominant	ADJ
easat-267	196	55	frequency	frequency	NOUN
easat-267	196	56	of	of	ADP
easat-267	196	57	g6pd	g6pd	NOUN
easat-267	196	58	deficiency	deficiency	NOUN
easat-267	196	59	over	over	ADP
easat-267	196	60	the	the	DET
easat-267	196	61	sickle	sickle	NOUN
easat-267	196	62	cell	cell	NOUN
easat-267	196	63	disorders	disorder	NOUN
easat-267	196	64	in	in	ADP
easat-267	196	65	some	some	DET
easat-267	196	66	aboriginal	aboriginal	ADJ
easat-267	196	67	communities	community	NOUN
easat-267	196	68	in	in	ADP
easat-267	196	69	india	india	PROPN
easat-267	196	70	.	.	PUNCT
easat-267	197	1	it	it	PRON
easat-267	197	2	seems	seem	VERB
easat-267	197	3	that	that	SCONJ
easat-267	197	4	the	the	DET
easat-267	197	5	replacement	replacement	NOUN
easat-267	197	6	of	of	ADP
easat-267	197	7	the	the	DET
easat-267	197	8	sickle	sickle	NOUN
easat-267	197	9	cell	cell	NOUN
easat-267	197	10	allele	allele	NOUN
easat-267	197	11	for	for	ADP
easat-267	197	12	g6pd	g6pd	NOUN
easat-267	197	13	deficiency	deficiency	NOUN
easat-267	197	14	allele	allele	NOUN
easat-267	197	15	is	be	AUX
easat-267	197	16	occurring	occur	VERB
easat-267	197	17	due	due	ADP
easat-267	197	18	to	to	ADP
easat-267	197	19	disequilibrium	disequilibrium	NOUN
easat-267	197	20	in	in	ADP
easat-267	197	21	the	the	DET
easat-267	197	22	major	major	ADJ
easat-267	197	23	scheduled	schedule	VERB
easat-267	197	24	castes	caste	NOUN
easat-267	197	25	/	/	SYM
easat-267	197	26	tribes	tribe	NOUN
easat-267	197	27	of	of	ADP
easat-267	197	28	chhattisgarh	chhattisgarh	NOUN
easat-267	197	29	,	,	PUNCT
easat-267	197	30	madhya	madhya	PROPN
easat-267	197	31	pradesh	pradesh	PROPN
easat-267	197	32	,	,	PUNCT
easat-267	197	33	maharashtra	maharashtra	PROPN
easat-267	197	34	,	,	PUNCT
easat-267	197	35	and	and	CCONJ
easat-267	197	36	odisha	odisha	PROPN
easat-267	197	37	state	state	NOUN
easat-267	197	38	in	in	ADP
easat-267	197	39	central	central	ADJ
easat-267	197	40	india	india	PROPN
easat-267	198	1	[	[	X
easat-267	198	2	2	2	NUM
easat-267	198	3	]	]	PUNCT
easat-267	198	4	.	.	PUNCT
easat-267	199	1	this	this	PRON
easat-267	199	2	means	mean	VERB
easat-267	199	3	that	that	SCONJ
easat-267	199	4	the	the	DET
easat-267	199	5	decrease	decrease	NOUN
easat-267	199	6	in	in	ADP
easat-267	199	7	sickle	sickle	NOUN
easat-267	199	8	cell	cell	NOUN
easat-267	199	9	allele	allele	NOUN
easat-267	199	10	is	be	AUX
easat-267	199	11	compensated	compensate	VERB
easat-267	199	12	by	by	ADP
easat-267	199	13	the	the	DET
easat-267	199	14	increase	increase	NOUN
easat-267	199	15	of	of	ADP
easat-267	199	16	g6pd	g6pd	NOUN
easat-267	199	17	deficiency	deficiency	NOUN
easat-267	199	18	alleles	allele	NOUN
easat-267	199	19	.	.	PUNCT
easat-267	200	1	it	it	PRON
easat-267	200	2	seems	seem	VERB
easat-267	200	3	that	that	SCONJ
easat-267	200	4	different	different	ADJ
easat-267	200	5	abnormal	abnormal	ADJ
easat-267	200	6	hemoglobin	hemoglobin	NOUN
easat-267	200	7	variants	variant	NOUN
easat-267	200	8	(	(	PUNCT
easat-267	200	9	c	c	X
easat-267	200	10	,	,	PUNCT
easat-267	200	11	d	d	NOUN
easat-267	200	12	,	,	PUNCT
easat-267	200	13	e	e	NOUN
easat-267	200	14	,	,	PUNCT
easat-267	200	15	f	f	PROPN
easat-267	200	16	,	,	PUNCT
easat-267	200	17	s	s	PART
easat-267	200	18	and	and	CCONJ
easat-267	200	19	thalassemias	thalassemia	NOUN
easat-267	200	20	)	)	PUNCT
easat-267	200	21	and	and	CCONJ
easat-267	200	22	g6pd	g6pd	NOUN
easat-267	200	23	enzyme	enzyme	NOUN
easat-267	200	24	deficiency	deficiency	NOUN
easat-267	200	25	are	be	AUX
easat-267	200	26	the	the	DET
easat-267	200	27	directed	direct	VERB
easat-267	200	28	mutations	mutation	NOUN
easat-267	200	29	against	against	ADP
easat-267	200	30	the	the	DET
easat-267	200	31	malaria	malaria	NOUN
easat-267	200	32	malady	malady	NOUN
easat-267	200	33	as	as	ADP
easat-267	200	34	the	the	DET
easat-267	200	35	heterozygotes	heterozygote	NOUN
easat-267	200	36	or	or	CCONJ
easat-267	200	37	carriers	carrier	NOUN
easat-267	200	38	of	of	ADP
easat-267	200	39	these	these	DET
easat-267	200	40	genetic	genetic	ADJ
easat-267	200	41	traits	trait	NOUN
easat-267	200	42	do	do	AUX
easat-267	200	43	not	not	PART
easat-267	200	44	suffer	suffer	VERB
easat-267	200	45	severely	severely	ADV
easat-267	200	46	from	from	ADP
easat-267	200	47	the	the	DET
easat-267	200	48	dreadful	dreadful	ADJ
easat-267	200	49	malaria	malaria	NOUN
easat-267	200	50	(	(	PUNCT
easat-267	200	51	tables	table	NOUN
easat-267	200	52	1	1	NUM
easat-267	200	53	-	-	SYM
easat-267	200	54	4	4	NUM
easat-267	200	55	)	)	PUNCT
easat-267	200	56	.	.	PUNCT
easat-267	201	1	another	another	DET
easat-267	201	2	important	important	ADJ
easat-267	201	3	factor	factor	NOUN
easat-267	201	4	is	be	AUX
easat-267	201	5	the	the	DET
easat-267	201	6	relatively	relatively	ADV
easat-267	201	7	high	high	ADJ
easat-267	201	8	frequency	frequency	NOUN
easat-267	201	9	of	of	ADP
easat-267	201	10	consanguineous	consanguineous	ADJ
easat-267	201	11	marriages	marriage	NOUN
easat-267	201	12	in	in	ADP
easat-267	201	13	many	many	ADJ
easat-267	201	14	regions	region	NOUN
easat-267	201	15	of	of	ADP
easat-267	201	16	india	india	PROPN
easat-267	201	17	with	with	ADP
easat-267	201	18	high	high	ADJ
easat-267	201	19	frequency	frequency	NOUN
easat-267	201	20	of	of	ADP
easat-267	201	21	these	these	DET
easat-267	201	22	red	red	ADJ
easat-267	201	23	cell	cell	NOUN
easat-267	201	24	genetic	genetic	ADJ
easat-267	201	25	variants	variant	NOUN
easat-267	201	26	;	;	PUNCT
easat-267	201	27	this	this	DET
easat-267	201	28	mechanism	mechanism	NOUN
easat-267	201	29	has	have	VERB
easat-267	201	30	an	an	DET
easat-267	201	31	important	important	ADJ
easat-267	201	32	effect	effect	NOUN
easat-267	201	33	on	on	ADP
easat-267	201	34	increasing	increase	VERB
easat-267	201	35	the	the	DET
easat-267	201	36	gene	gene	NOUN
easat-267	201	37	frequency	frequency	NOUN
easat-267	201	38	of	of	ADP
easat-267	201	39	the	the	DET
easat-267	201	40	fore	fore	NOUN
easat-267	201	41	said	say	VERB
easat-267	201	42	recessively	recessively	ADV
easat-267	201	43	inherited	inherit	VERB
easat-267	201	44	disorders	disorder	NOUN
easat-267	201	45	in	in	ADP
easat-267	201	46	vulnerable	vulnerable	ADJ
easat-267	201	47	populations	population	NOUN
easat-267	201	48	of	of	ADP
easat-267	201	49	central	central	ADJ
easat-267	201	50	india	india	PROPN
easat-267	202	1	[	[	X
easat-267	202	2	50,51	50,51	NOUN
easat-267	202	3	]	]	PUNCT
easat-267	202	4	.	.	PUNCT
easat-267	203	1	although	although	SCONJ
easat-267	203	2	accurate	accurate	ADJ
easat-267	203	3	data	datum	NOUN
easat-267	203	4	on	on	ADP
easat-267	203	5	the	the	DET
easat-267	203	6	frequency	frequency	NOUN
easat-267	203	7	of	of	ADP
easat-267	203	8	consanguineous	consanguineous	ADJ
easat-267	203	9	marriages	marriage	NOUN
easat-267	203	10	are	be	AUX
easat-267	203	11	lacking	lack	VERB
easat-267	203	12	,	,	PUNCT
easat-267	203	13	there	there	PRON
easat-267	203	14	is	be	VERB
easat-267	203	15	no	no	DET
easat-267	203	16	doubt	doubt	NOUN
easat-267	203	17	that	that	SCONJ
easat-267	203	18	this	this	PRON
easat-267	203	19	is	be	AUX
easat-267	203	20	an	an	DET
easat-267	203	21	important	important	ADJ
easat-267	203	22	factor	factor	NOUN
easat-267	203	23	in	in	ADP
easat-267	203	24	helping	help	VERB
easat-267	203	25	to	to	PART
easat-267	203	26	maintain	maintain	VERB
easat-267	203	27	the	the	DET
easat-267	203	28	global	global	ADJ
easat-267	203	29	or	or	CCONJ
easat-267	203	30	regional	regional	ADJ
easat-267	203	31	or	or	CCONJ
easat-267	203	32	local	local	ADJ
easat-267	203	33	health	health	NOUN
easat-267	203	34	problem	problem	NOUN
easat-267	203	35	posed	pose	VERB
easat-267	203	36	by	by	ADP
easat-267	203	37	the	the	DET
easat-267	203	38	high	high	ADJ
easat-267	203	39	frequency	frequency	NOUN
easat-267	203	40	of	of	ADP
easat-267	203	41	red	red	ADJ
easat-267	203	42	cell	cell	NOUN
easat-267	203	43	genetic	genetic	ADJ
easat-267	203	44	variants	variant	NOUN
easat-267	203	45	and	and	CCONJ
easat-267	203	46	malaria	malaria	NOUN
easat-267	203	47	conditions	condition	NOUN
easat-267	203	48	,	,	PUNCT
easat-267	203	49	and	and	CCONJ
easat-267	203	50	significantly	significantly	ADV
easat-267	203	51	contributing	contribute	VERB
easat-267	203	52	towards	towards	ADP
easat-267	203	53	the	the	DET
easat-267	203	54	high	high	ADJ
easat-267	203	55	morbidity	morbidity	NOUN
easat-267	203	56	,	,	PUNCT
easat-267	203	57	maternal	maternal	ADJ
easat-267	203	58	mortality	mortality	NOUN
easat-267	203	59	,	,	PUNCT
easat-267	203	60	and	and	CCONJ
easat-267	203	61	fetal	fetal	ADJ
easat-267	203	62	and	and	CCONJ
easat-267	203	63	childhood	childhood	NOUN
easat-267	203	64	mortality	mortality	NOUN
easat-267	203	65	[	[	X
easat-267	203	66	21,22,37,38	21,22,37,38	NUM
easat-267	203	67	]	]	PUNCT
easat-267	203	68	.	.	PUNCT
easat-267	204	1	the	the	DET
easat-267	204	2	varying	vary	VERB
easat-267	204	3	distribution	distribution	NOUN
easat-267	204	4	of	of	ADP
easat-267	204	5	some	some	PRON
easat-267	204	6	of	of	ADP
easat-267	204	7	the	the	DET
easat-267	204	8	hemoglobin	hemoglobin	NOUN
easat-267	204	9	disorders	disorder	NOUN
easat-267	204	10	,	,	PUNCT
easat-267	204	11	and	and	CCONJ
easat-267	204	12	g6pd	g6pd	NOUN
easat-267	204	13	enzyme	enzyme	NOUN
easat-267	204	14	deficiency	deficiency	NOUN
easat-267	204	15	reflects	reflect	VERB
easat-267	204	16	strong	strong	ADJ
easat-267	204	17	founder	founder	NOUN
easat-267	204	18	effects	effect	NOUN
easat-267	204	19	of	of	ADP
easat-267	204	20	their	their	PRON
easat-267	204	21	original	original	ADJ
easat-267	204	22	inhabitants	inhabitant	NOUN
easat-267	204	23	in	in	ADP
easat-267	204	24	different	different	ADJ
easat-267	204	25	populations	population	NOUN
easat-267	204	26	[	[	X
easat-267	204	27	6,8	6,8	NUM
easat-267	204	28	]	]	PUNCT
easat-267	204	29	.	.	PUNCT
easat-267	205	1	another	another	DET
easat-267	205	2	important	important	ADJ
easat-267	205	3	factor	factor	NOUN
easat-267	205	4	is	be	AUX
easat-267	205	5	the	the	DET
easat-267	205	6	epidemiological	epidemiological	ADJ
easat-267	205	7	conditions	condition	NOUN
easat-267	205	8	,	,	PUNCT
easat-267	205	9	whereby	whereby	SCONJ
easat-267	205	10	as	as	SCONJ
easat-267	205	11	the	the	DET
easat-267	205	12	public	public	ADJ
easat-267	205	13	health	health	NOUN
easat-267	205	14	and	and	CCONJ
easat-267	205	15	nutritional	nutritional	ADJ
easat-267	205	16	standards	standard	NOUN
easat-267	205	17	improve	improve	VERB
easat-267	205	18	in	in	ADP
easat-267	205	19	the	the	DET
easat-267	205	20	poorer	poor	ADJ
easat-267	205	21	countries	country	NOUN
easat-267	205	22	,	,	PUNCT
easat-267	205	23	babies	baby	NOUN
easat-267	205	24	with	with	ADP
easat-267	205	25	these	these	DET
easat-267	205	26	red	red	ADJ
easat-267	205	27	cell	cell	NOUN
easat-267	205	28	hemolytic	hemolytic	ADJ
easat-267	205	29	conditions	condition	NOUN
easat-267	205	30	who	who	PRON
easat-267	205	31	would	would	AUX
easat-267	205	32	,	,	PUNCT
easat-267	205	33	otherwise	otherwise	ADV
easat-267	205	34	,	,	PUNCT
easat-267	205	35	have	have	AUX
easat-267	205	36	died	die	VERB
easat-267	205	37	in	in	ADP
easat-267	205	38	early	early	ADJ
easat-267	205	39	life	life	NOUN
easat-267	205	40	,	,	PUNCT
easat-267	205	41	are	be	AUX
easat-267	205	42	now	now	ADV
easat-267	205	43	living	live	VERB
easat-267	205	44	long	long	ADV
easat-267	205	45	enough	enough	ADV
easat-267	205	46	to	to	PART
easat-267	205	47	present	present	VERB
easat-267	205	48	for	for	ADP
easat-267	205	49	diagnosis	diagnosis	NOUN
easat-267	205	50	and	and	CCONJ
easat-267	205	51	management	management	NOUN
easat-267	206	1	[	[	X
easat-267	206	2	21	21	NUM
easat-267	206	3	]	]	PUNCT
easat-267	206	4	.	.	PUNCT
easat-267	207	1	an	an	DET
easat-267	207	2	estimated	estimate	VERB
easat-267	207	3	400	400	NUM
easat-267	207	4	million	million	NUM
easat-267	207	5	people	people	NOUN
easat-267	207	6	worldwide	worldwide	ADV
easat-267	207	7	have	have	VERB
easat-267	207	8	g6pd	g6pd	NOUN
easat-267	207	9	deficiency	deficiency	NOUN
easat-267	207	10	.	.	PUNCT
easat-267	208	1	this	this	DET
easat-267	208	2	condition	condition	NOUN
easat-267	208	3	occurs	occur	VERB
easat-267	208	4	most	most	ADV
easat-267	208	5	frequently	frequently	ADV
easat-267	208	6	in	in	ADP
easat-267	208	7	certain	certain	ADJ
easat-267	208	8	parts	part	NOUN
easat-267	208	9	of	of	ADP
easat-267	208	10	africa	africa	PROPN
easat-267	208	11	,	,	PUNCT
easat-267	208	12	southeast	southeast	PROPN
easat-267	208	13	asia	asia	PROPN
easat-267	208	14	including	include	VERB
easat-267	208	15	india	india	PROPN
easat-267	208	16	,	,	PUNCT
easat-267	208	17	the	the	DET
easat-267	208	18	mediterranean	mediterranean	PROPN
easat-267	208	19	,	,	PUNCT
easat-267	208	20	and	and	CCONJ
easat-267	208	21	the	the	DET
easat-267	208	22	middle	middle	PROPN
easat-267	208	23	east	east	PROPN
easat-267	208	24	.	.	PUNCT
easat-267	209	1	it	it	PRON
easat-267	209	2	affects	affect	VERB
easat-267	209	3	about	about	ADV
easat-267	209	4	1/10	1/10	NUM
easat-267	209	5	african	african	ADJ
easat-267	209	6	american	american	ADJ
easat-267	209	7	males	male	NOUN
easat-267	209	8	in	in	ADP
easat-267	209	9	united	united	PROPN
easat-267	209	10	states	states	PROPN
easat-267	210	1	[	[	X
easat-267	210	2	17,41	17,41	NUM
easat-267	210	3	]	]	SYM
easat-267	210	4	.	.	PUNCT
easat-267	211	1	1.10	1.10	NUM
easat-267	211	2	.	.	PUNCT
easat-267	212	1	concluding	conclude	VERB
easat-267	212	2	comments	comment	NOUN
easat-267	212	3	the	the	DET
easat-267	212	4	frequency	frequency	NOUN
easat-267	212	5	distribution	distribution	NOUN
easat-267	212	6	of	of	ADP
easat-267	212	7	inherited	inherit	VERB
easat-267	212	8	hemoglobin	hemoglobin	NOUN
easat-267	212	9	disorders	disorder	NOUN
easat-267	212	10	and	and	CCONJ
easat-267	212	11	plasmodium	plasmodium	NOUN
easat-267	212	12	falciparum	falciparum	ADJ
easat-267	212	13	malaria	malaria	NOUN
easat-267	212	14	are	be	AUX
easat-267	212	15	posing	pose	VERB
easat-267	212	16	increased	increase	VERB
easat-267	212	17	burden	burden	NOUN
easat-267	212	18	on	on	ADP
easat-267	212	19	human	human	ADJ
easat-267	212	20	health	health	NOUN
easat-267	212	21	resources	resource	NOUN
easat-267	212	22	.	.	PUNCT
easat-267	213	1	their	their	PRON
easat-267	213	2	high	high	ADJ
easat-267	213	3	frequency	frequency	NOUN
easat-267	213	4	is	be	AUX
easat-267	213	5	a	a	DET
easat-267	213	6	reflection	reflection	NOUN
easat-267	213	7	of	of	ADP
easat-267	213	8	natural	natural	ADJ
easat-267	213	9	selection	selection	NOUN
easat-267	213	10	combined	combine	VERB
easat-267	213	11	with	with	ADP
easat-267	213	12	a	a	DET
easat-267	213	13	high	high	ADJ
easat-267	213	14	frequency	frequency	NOUN
easat-267	213	15	of	of	ADP
easat-267	213	16	consanguineous	consanguineous	ADJ
easat-267	213	17	marriages	marriage	NOUN
easat-267	213	18	in	in	ADP
easat-267	213	19	many	many	ADJ
easat-267	213	20	communities	community	NOUN
easat-267	213	21	and	and	CCONJ
easat-267	213	22	regions	region	NOUN
easat-267	213	23	,	,	PUNCT
easat-267	213	24	together	together	ADV
easat-267	213	25	with	with	ADP
easat-267	213	26	an	an	DET
easat-267	213	27	epidemiological	epidemiological	ADJ
easat-267	213	28	expansion	expansion	NOUN
easat-267	213	29	due	due	ADP
easat-267	213	30	to	to	ADP
easat-267	213	31	public	public	ADJ
easat-267	213	32	health	health	NOUN
easat-267	213	33	improvement	improvement	NOUN
easat-267	213	34	in	in	ADP
easat-267	213	35	the	the	DET
easat-267	213	36	affected	affected	ADJ
easat-267	213	37	communities	community	NOUN
easat-267	213	38	as	as	SCONJ
easat-267	213	39	more	more	ADJ
easat-267	213	40	babies	baby	NOUN
easat-267	213	41	with	with	ADP
easat-267	213	42	these	these	DET
easat-267	213	43	disorders	disorder	NOUN
easat-267	213	44	survive	survive	VERB
easat-267	213	45	to	to	PART
easat-267	213	46	present	present	VERB
easat-267	213	47	for	for	ADP
easat-267	213	48	treatment	treatment	NOUN
easat-267	213	49	in	in	ADP
easat-267	213	50	future	future	NOUN
easat-267	213	51	too	too	ADV
easat-267	213	52	.	.	PUNCT
easat-267	214	1	the	the	DET
easat-267	214	2	strongest	strong	ADJ
easat-267	214	3	evidence	evidence	NOUN
easat-267	214	4	for	for	ADP
easat-267	214	5	hb	hb	PROPN
easat-267	214	6	s	s	PART
easat-267	214	7	and	and	CCONJ
easat-267	214	8	(	(	PUNCT
easat-267	214	9	α+)and	α+)and	NOUN
easat-267	214	10	(	(	PUNCT
easat-267	214	11	β+)-thalassemias	β+)-thalassemias	PROPN
easat-267	214	12	,	,	PUNCT
easat-267	214	13	without	without	ADP
easat-267	214	14	any	any	DET
easat-267	214	15	doubt	doubt	NOUN
easat-267	214	16	,	,	PUNCT
easat-267	214	17	that	that	SCONJ
easat-267	214	18	malaria	malaria	NOUN
easat-267	214	19	is	be	AUX
easat-267	214	20	responsible	responsible	ADJ
easat-267	214	21	for	for	ADP
easat-267	214	22	the	the	DET
easat-267	214	23	current	current	ADJ
easat-267	214	24	distributions	distribution	NOUN
easat-267	214	25	of	of	ADP
easat-267	214	26	all	all	DET
easat-267	214	27	the	the	DET
easat-267	214	28	major	major	ADJ
easat-267	214	29	hemoglobin	hemoglobin	NOUN
easat-267	214	30	disorders	disorder	NOUN
easat-267	214	31	in	in	ADP
easat-267	214	32	the	the	DET
easat-267	214	33	world	world	NOUN
easat-267	214	34	.	.	PUNCT
easat-267	215	1	malaria	malaria	NOUN
easat-267	215	2	is	be	AUX
easat-267	215	3	one	one	NUM
easat-267	215	4	of	of	ADP
easat-267	215	5	the	the	DET
easat-267	215	6	leading	lead	VERB
easat-267	215	7	causes	cause	NOUN
easat-267	215	8	of	of	ADP
easat-267	215	9	death	death	NOUN
easat-267	215	10	worldwide	worldwide	ADV
easat-267	215	11	and	and	CCONJ
easat-267	215	12	has	have	AUX
easat-267	215	13	been	be	AUX
easat-267	215	14	suggested	suggest	VERB
easat-267	215	15	as	as	ADP
easat-267	215	16	the	the	DET
easat-267	215	17	most	most	ADV
easat-267	215	18	potent	potent	ADJ
easat-267	215	19	type	type	NOUN
easat-267	215	20	of	of	ADP
easat-267	215	21	selection	selection	NOUN
easat-267	215	22	in	in	ADP
easat-267	215	23	humans	human	NOUN
easat-267	215	24	in	in	ADP
easat-267	215	25	recent	recent	ADJ
easat-267	215	26	millennia	millennia	NOUN
easat-267	215	27	.	.	PUNCT
easat-267	216	1	as	as	ADP
easat-267	216	2	a	a	DET
easat-267	216	3	result	result	NOUN
easat-267	216	4	,	,	PUNCT
easat-267	216	5	genes	gene	NOUN
easat-267	216	6	involved	involve	VERB
easat-267	216	7	in	in	ADP
easat-267	216	8	malaria	malaria	NOUN
easat-267	216	9	resistance	resistance	NOUN
easat-267	216	10	are	be	AUX
easat-267	216	11	excellent	excellent	ADJ
easat-267	216	12	examples	example	NOUN
easat-267	216	13	of	of	ADP
easat-267	216	14	strong	strong	ADJ
easat-267	216	15	selection	selection	NOUN
easat-267	216	16	in	in	ADP
easat-267	216	17	recent	recent	ADJ
easat-267	216	18	years	year	NOUN
easat-267	216	19	.	.	PUNCT
easat-267	217	1	perhaps	perhaps	ADV
easat-267	217	2	best	well	ADV
easat-267	217	3	known	know	VERB
easat-267	217	4	is	be	AUX
easat-267	217	5	the	the	DET
easat-267	217	6	sickle	sickle	NOUN
easat-267	217	7	cell	cell	NOUN
easat-267	217	8	hemoglobin	hemoglobin	NOUN
easat-267	217	9	variant	variant	NOUN
easat-267	217	10	,	,	PUNCT
easat-267	217	11	which	which	PRON
easat-267	217	12	is	be	AUX
easat-267	217	13	often	often	ADV
easat-267	217	14	used	use	VERB
easat-267	217	15	as	as	ADP
easat-267	217	16	an	an	DET
easat-267	217	17	example	example	NOUN
easat-267	217	18	of	of	ADP
easat-267	217	19	heterozygote	heterozygote	NOUN
easat-267	217	20	advantage	advantage	NOUN
easat-267	217	21	.	.	PUNCT
easat-267	218	1	in	in	ADP
easat-267	218	2	addition	addition	NOUN
easat-267	218	3	,	,	PUNCT
easat-267	218	4	g6pd	g6pd	NOUN
easat-267	218	5	deficiency	deficiency	NOUN
easat-267	218	6	illustrates	illustrate	VERB
easat-267	218	7	strong	strong	ADJ
easat-267	218	8	selection	selection	NOUN
easat-267	218	9	at	at	ADP
easat-267	218	10	an	an	DET
easat-267	218	11	x	x	ADV
easat-267	218	12	-	-	ADJ
easat-267	218	13	linked	link	VERB
easat-267	218	14	locus	locus	NOUN
easat-267	218	15	,	,	PUNCT
easat-267	218	16	followed	follow	VERB
easat-267	218	17	by	by	ADP
easat-267	218	18	β	β	ADJ
easat-267	218	19	-	-	ADJ
easat-267	218	20	globin	globin	ADJ
easat-267	218	21	variants	variant	NOUN
easat-267	218	22	c	c	X
easat-267	218	23	,	,	PUNCT
easat-267	218	24	d	d	NOUN
easat-267	218	25	,	,	PUNCT
easat-267	218	26	e	e	NOUN
easat-267	218	27	and	and	CCONJ
easat-267	218	28	s	s	VERB
easat-267	218	29	variants	variant	NOUN
easat-267	218	30	.	.	PUNCT
easat-267	219	1	in	in	ADP
easat-267	219	2	1949	1949	NUM
easat-267	219	3	,	,	PUNCT
easat-267	219	4	haldane	haldane	PROPN
easat-267	219	5	initially	initially	ADV
easat-267	219	6	suggested	suggest	VERB
easat-267	219	7	that	that	SCONJ
easat-267	219	8	infectious	infectious	ADJ
easat-267	219	9	disease	disease	NOUN
easat-267	219	10	;	;	PUNCT
easat-267	219	11	specifically	specifically	ADV
easat-267	219	12	the	the	DET
easat-267	219	13	malaria	malaria	NOUN
easat-267	219	14	could	could	AUX
easat-267	219	15	be	be	AUX
easat-267	219	16	a	a	DET
easat-267	219	17	strong	strong	ADJ
easat-267	219	18	selective	selective	ADJ
easat-267	219	19	force	force	NOUN
easat-267	219	20	in	in	ADP
easat-267	219	21	human	human	ADJ
easat-267	219	22	populations	population	NOUN
easat-267	219	23	.	.	PUNCT
easat-267	220	1	evidence	evidence	NOUN
easat-267	220	2	for	for	ADP
easat-267	220	3	the	the	DET
easat-267	220	4	strong	strong	ADJ
easat-267	220	5	selective	selective	ADJ
easat-267	220	6	effect	effect	NOUN
easat-267	220	7	of	of	ADP
easat-267	220	8	malaria	malaria	NOUN
easat-267	220	9	resistance	resistance	NOUN
easat-267	220	10	includes	include	VERB
easat-267	220	11	the	the	DET
easat-267	220	12	high	high	ADJ
easat-267	220	13	frequency	frequency	NOUN
easat-267	220	14	of	of	ADP
easat-267	220	15	a	a	DET
easat-267	220	16	number	number	NOUN
easat-267	220	17	of	of	ADP
easat-267	220	18	detrimental	detrimental	ADJ
easat-267	220	19	genetic	genetic	ADJ
easat-267	220	20	diseases	disease	NOUN
easat-267	220	21	caused	cause	VERB
easat-267	220	22	by	by	ADP
easat-267	220	23	the	the	DET
easat-267	220	24	pleiotropic	pleiotropic	ADJ
easat-267	220	25	effects	effect	NOUN
easat-267	220	26	of	of	ADP
easat-267	220	27	these	these	DET
easat-267	220	28	malaria	malaria	ADJ
easat-267	220	29	resistance	resistance	NOUN
easat-267	220	30	variants	variant	NOUN
easat-267	220	31	.	.	PUNCT
easat-267	221	1	in	in	ADP
easat-267	221	2	contrast	contrast	NOUN
easat-267	221	3	,	,	PUNCT
easat-267	221	4	there	there	PRON
easat-267	221	5	are	be	VERB
easat-267	221	6	many	many	ADJ
easat-267	221	7	changes	change	NOUN
easat-267	221	8	that	that	PRON
easat-267	221	9	modify	modify	VERB
easat-267	221	10	levels	level	NOUN
easat-267	221	11	of	of	ADP
easat-267	221	12	expression	expression	NOUN
easat-267	221	13	and	and	CCONJ
easat-267	221	14	provide	provide	VERB
easat-267	221	15	malaria	malaria	NOUN
easat-267	221	16	resistance	resistance	NOUN
easat-267	221	17	for	for	ADP
easat-267	221	18	g6pd	g6pd	NOUN
easat-267	221	19	deficiency	deficiency	NOUN
easat-267	221	20	,	,	PUNCT
easat-267	221	21	α	α	NOUN
easat-267	221	22	-	-	PUNCT
easat-267	221	23	thalassemia	thalassemia	NOUN
easat-267	221	24	,	,	PUNCT
easat-267	221	25	and	and	CCONJ
easat-267	221	26	β	β	NOUN
easat-267	221	27	-	-	NOUN
easat-267	221	28	thalassemia	thalassemia	NOUN
easat-267	221	29	.	.	PUNCT
easat-267	222	1	malaria	malaria	NOUN
easat-267	222	2	parasites	parasite	NOUN
easat-267	222	3	have	have	AUX
easat-267	222	4	co	co	VERB
easat-267	222	5	-	-	VERB
easat-267	222	6	evolved	evolve	VERB
easat-267	222	7	with	with	ADP
easat-267	222	8	the	the	DET
easat-267	222	9	host	host	NOUN
easat-267	222	10	and	and	CCONJ
easat-267	222	11	constitute	constitute	VERB
easat-267	222	12	an	an	DET
easat-267	222	13	important	important	ADJ
easat-267	222	14	deriving	derive	VERB
easat-267	222	15	evolutionary	evolutionary	ADJ
easat-267	222	16	force	force	NOUN
easat-267	222	17	behind	behind	ADP
easat-267	222	18	common	common	ADJ
easat-267	222	19	erythrocyte	erythrocyte	NOUN
easat-267	222	20	variants	variant	NOUN
easat-267	222	21	such	such	ADJ
easat-267	222	22	as	as	ADP
easat-267	222	23	thalassemia	thalassemia	NOUN
easat-267	222	24	,	,	PUNCT
easat-267	222	25	sickle	sickle	NOUN
easat-267	222	26	cell	cell	NOUN
easat-267	222	27	disease	disease	NOUN
easat-267	222	28	,	,	PUNCT
easat-267	222	29	hb	hb	PROPN
easat-267	222	30	c	c	PROPN
easat-267	222	31	,	,	PUNCT
easat-267	222	32	hb	hb	PROPN
easat-267	222	33	d	d	PROPN
easat-267	222	34	,	,	PUNCT
easat-267	222	35	hb	hb	PROPN
easat-267	222	36	e	e	PROPN
easat-267	222	37	and	and	CCONJ
easat-267	222	38	g6pd	g6pd	NOUN
easat-267	222	39	deficiency	deficiency	NOUN
easat-267	222	40	and	and	CCONJ
easat-267	222	41	other	other	ADJ
easat-267	222	42	erythrocyte	erythrocyte	NOUN
easat-267	222	43	anomalies	anomaly	NOUN
easat-267	222	44	.	.	PUNCT
easat-267	223	1	host	host	NOUN
easat-267	223	2	-	-	PUNCT
easat-267	223	3	parasite	parasite	NOUN
easat-267	223	4	interactions	interaction	NOUN
easat-267	223	5	have	have	AUX
easat-267	223	6	led	lead	VERB
easat-267	223	7	to	to	ADP
easat-267	223	8	a	a	DET
easat-267	223	9	host	host	NOUN
easat-267	223	10	’s	’s	PART
easat-267	223	11	relative	relative	ADJ
easat-267	223	12	resistance	resistance	NOUN
easat-267	223	13	to	to	ADP
easat-267	223	14	the	the	DET
easat-267	223	15	parasite	parasite	NOUN
easat-267	223	16	.	.	PUNCT
easat-267	224	1	there	there	PRON
easat-267	224	2	could	could	AUX
easat-267	224	3	be	be	AUX
easat-267	224	4	two	two	NUM
easat-267	224	5	reasons	reason	NOUN
easat-267	224	6	for	for	ADP
easat-267	224	7	malaria	malaria	NOUN
easat-267	224	8	mediated	mediate	VERB
easat-267	224	9	evolutionary	evolutionary	ADJ
easat-267	224	10	selection	selection	NOUN
easat-267	224	11	:	:	PUNCT
easat-267	224	12	•	•	NUM
easat-267	224	13	strong	strong	ADJ
easat-267	224	14	selective	selective	ADJ
easat-267	224	15	pressure	pressure	NOUN
easat-267	224	16	in	in	ADP
easat-267	224	17	case	case	NOUN
easat-267	224	18	of	of	ADP
easat-267	224	19	higher	high	ADJ
easat-267	224	20	frequency	frequency	NOUN
easat-267	224	21	of	of	ADP
easat-267	224	22	hb	hb	PROPN
easat-267	224	23	s	s	PROPN
easat-267	224	24	allele	allele	NOUN
easat-267	224	25	found	find	VERB
easat-267	224	26	in	in	ADP
easat-267	224	27	malaria	malaria	NOUN
easat-267	224	28	exposed	expose	VERB
easat-267	224	29	populations	population	NOUN
easat-267	224	30	;	;	PUNCT
easat-267	224	31	and	and	CCONJ
easat-267	224	32	•	•	NUM
easat-267	224	33	independent	independent	ADJ
easat-267	224	34	evolutionary	evolutionary	ADJ
easat-267	224	35	responses	response	NOUN
easat-267	224	36	developed	develop	VERB
easat-267	224	37	by	by	ADP
easat-267	224	38	different	different	ADJ
easat-267	224	39	populations	population	NOUN
easat-267	224	40	both	both	CCONJ
easat-267	224	41	at	at	ADP
easat-267	224	42	global	global	ADJ
easat-267	224	43	(	(	PUNCT
easat-267	224	44	e.g.	e.g.	ADV
easat-267	224	45	hb	hb	X
easat-267	224	46	c	c	PROPN
easat-267	224	47	,	,	PUNCT
easat-267	224	48	hb	hb	PROPN
easat-267	224	49	d	d	PROPN
easat-267	224	50	,	,	PUNCT
easat-267	224	51	hb	hb	PROPN
easat-267	224	52	e	e	PROPN
easat-267	224	53	and	and	CCONJ
easat-267	224	54	hb	hb	PROPN
easat-267	224	55	s	s	PROPN
easat-267	224	56	confer	confer	NOUN
easat-267	224	57	protection	protection	NOUN
easat-267	224	58	against	against	ADP
easat-267	224	59	malaria	malaria	NOUN
easat-267	224	60	because	because	SCONJ
easat-267	224	61	mutations	mutation	NOUN
easat-267	224	62	affect	affect	VERB
easat-267	224	63	the	the	DET
easat-267	224	64	hemoglobin	hemoglobin	NOUN
easat-267	224	65	functionality	functionality	NOUN
easat-267	224	66	)	)	PUNCT
easat-267	224	67	and	and	CCONJ
easat-267	224	68	local	local	ADJ
easat-267	224	69	level	level	NOUN
easat-267	224	70	(	(	PUNCT
easat-267	224	71	four	four	NUM
easat-267	224	72	different	different	ADJ
easat-267	224	73	hbs	hbs	PROPN
easat-267	224	74	haplotypes	haplotype	NOUN
easat-267	224	75	found	find	VERB
easat-267	224	76	in	in	ADP
easat-267	224	77	africa	africa	PROPN
easat-267	224	78	)	)	PUNCT
easat-267	224	79	and	and	CCONJ
easat-267	224	80	the	the	DET
easat-267	224	81	arab	arab	PROPN
easat-267	224	82	-	-	PUNCT
easat-267	224	83	indian	indian	ADJ
easat-267	224	84	haplotype	haplotype	NOUN
easat-267	224	85	is	be	AUX
easat-267	224	86	different	different	ADJ
easat-267	224	87	from	from	ADP
easat-267	224	88	the	the	DET
easat-267	224	89	african	african	ADJ
easat-267	224	90	haplotypes	haplotype	NOUN
easat-267	224	91	.	.	PUNCT
easat-267	225	1	different	different	ADJ
easat-267	225	2	mechanisms	mechanism	NOUN
easat-267	225	3	conferring	confer	VERB
easat-267	225	4	protection	protection	NOUN
easat-267	225	5	against	against	ADP
easat-267	225	6	malaria	malaria	NOUN
easat-267	225	7	are	be	AUX
easat-267	225	8	widely	widely	ADV
easat-267	225	9	found	find	VERB
easat-267	225	10	in	in	ADP
easat-267	225	11	different	different	ADJ
easat-267	225	12	populations	population	NOUN
easat-267	225	13	of	of	ADP
easat-267	225	14	the	the	DET
easat-267	225	15	world	world	NOUN
easat-267	225	16	,	,	PUNCT
easat-267	225	17	and	and	CCONJ
easat-267	225	18	that	that	SCONJ
easat-267	225	19	the	the	DET
easat-267	225	20	populations	population	NOUN
easat-267	225	21	have	have	AUX
easat-267	225	22	evolved	evolve	VERB
easat-267	225	23	and	and	CCONJ
easat-267	225	24	developed	develop	VERB
easat-267	225	25	different	different	ADJ
easat-267	225	26	genetic	genetic	ADJ
easat-267	225	27	variants	variant	NOUN
easat-267	225	28	,	,	PUNCT
easat-267	225	29	which	which	PRON
easat-267	225	30	are	be	AUX
easat-267	225	31	related	relate	VERB
easat-267	225	32	to	to	ADP
easat-267	225	33	resistance	resistance	NOUN
easat-267	225	34	to	to	ADP
easat-267	225	35	the	the	DET
easat-267	225	36	malaria	malaria	NOUN
easat-267	225	37	disease	disease	NOUN
easat-267	225	38	.	.	PUNCT
easat-267	226	1	this	this	PRON
easat-267	226	2	could	could	AUX
easat-267	226	3	imply	imply	VERB
easat-267	226	4	that	that	SCONJ
easat-267	226	5	the	the	DET
easat-267	226	6	maintenance	maintenance	NOUN
easat-267	226	7	of	of	ADP
easat-267	226	8	these	these	DET
easat-267	226	9	alleles	allele	NOUN
easat-267	226	10	in	in	ADP
easat-267	226	11	the	the	DET
easat-267	226	12	population	population	NOUN
easat-267	226	13	has	have	AUX
easat-267	226	14	been	be	AUX
easat-267	226	15	due	due	ADJ
easat-267	226	16	to	to	ADP
easat-267	226	17	the	the	DET
easat-267	226	18	effects	effect	NOUN
easat-267	226	19	of	of	ADP
easat-267	226	20	positive	positive	ADJ
easat-267	226	21	selection	selection	NOUN
easat-267	226	22	against	against	ADP
easat-267	226	23	the	the	DET
easat-267	226	24	lethal	lethal	ADJ
easat-267	226	25	malaria	malaria	NOUN
easat-267	226	26	.	.	PUNCT
easat-267	227	1	there	there	PRON
easat-267	227	2	also	also	ADV
easat-267	227	3	seems	seem	VERB
easat-267	227	4	to	to	PART
easat-267	227	5	be	be	AUX
easat-267	227	6	disequilibrium	disequilibrium	NOUN
easat-267	227	7	and	and	CCONJ
easat-267	227	8	competition	competition	NOUN
easat-267	227	9	between	between	ADP
easat-267	227	10	two	two	NUM
easat-267	227	11	red	red	ADJ
easat-267	227	12	cell	cell	NOUN
easat-267	227	13	variants	variant	NOUN
easat-267	227	14	,	,	PUNCT
easat-267	227	15	i.	i.	PROPN
easat-267	227	16	e.	e.	PROPN
easat-267	227	17	sickle	sickle	PROPN
easat-267	227	18	cell	cell	PROPN
easat-267	227	19	disease	disease	NOUN
easat-267	227	20	(	(	PUNCT
easat-267	227	21	hb	hb	PROPN
easat-267	227	22	ss	ss	PROPN
easat-267	227	23	)	)	PUNCT
easat-267	227	24	and	and	CCONJ
easat-267	227	25	g6pd	g6pd	NOUN
easat-267	227	26	enzyme	enzyme	NOUN
easat-267	227	27	deficiency	deficiency	NOUN
easat-267	227	28	.	.	PUNCT
easat-267	228	1	when	when	SCONJ
easat-267	228	2	the	the	DET
easat-267	228	3	frequency	frequency	NOUN
easat-267	228	4	of	of	ADP
easat-267	228	5	sickle	sickle	PROPN
easat-267	228	6	cell	cell	NOUN
easat-267	228	7	allele	allele	NOUN
easat-267	228	8	decreases	decrease	VERB
easat-267	228	9	in	in	ADP
easat-267	228	10	malaria	malaria	ADJ
easat-267	228	11	endemic	endemic	ADJ
easat-267	228	12	tribal	tribal	ADJ
easat-267	228	13	population	population	NOUN
easat-267	228	14	in	in	ADP
easat-267	228	15	india	india	PROPN
easat-267	228	16	,	,	PUNCT
easat-267	228	17	the	the	DET
easat-267	228	18	frequency	frequency	NOUN
easat-267	228	19	of	of	ADP
easat-267	228	20	g6pd	g6pd	NOUN
easat-267	228	21	enzyme	enzyme	NOUN
easat-267	228	22	deficiency	deficiency	NOUN
easat-267	228	23	allele	allele	NOUN
easat-267	228	24	increases	increase	NOUN
easat-267	228	25	and	and	CCONJ
easat-267	228	26	vice	vice	NOUN
easat-267	228	27	versa	versa	ADV
easat-267	228	28	.	.	PUNCT
easat-267	229	1	this	this	DET
easat-267	229	2	trend	trend	NOUN
easat-267	229	3	for	for	ADP
easat-267	229	4	an	an	DET
easat-267	229	5	inverse	inverse	NOUN
easat-267	229	6	relationship	relationship	NOUN
easat-267	229	7	between	between	ADP
easat-267	229	8	sickle	sickle	NOUN
easat-267	229	9	cell	cell	NOUN
easat-267	229	10	disorders	disorder	NOUN
easat-267	229	11	and	and	CCONJ
easat-267	229	12	g6pd	g6pd	NOUN
easat-267	229	13	deficiency	deficiency	NOUN
easat-267	229	14	in	in	ADP
easat-267	229	15	major	major	ADJ
easat-267	229	16	scheduled	schedule	VERB
easat-267	229	17	caste	caste	NOUN
easat-267	229	18	and	and	CCONJ
easat-267	229	19	tribal	tribal	ADJ
easat-267	229	20	communities	community	NOUN
easat-267	229	21	of	of	ADP
easat-267	229	22	central	central	ADJ
easat-267	229	23	-	-	PUNCT
easat-267	229	24	eastern	eastern	ADJ
easat-267	229	25	india	india	PROPN
easat-267	229	26	,	,	PUNCT
easat-267	229	27	is	be	AUX
easat-267	229	28	fascinating	fascinating	ADJ
easat-267	229	29	one	one	NUM
easat-267	229	30	.	.	PUNCT
easat-267	230	1	since	since	SCONJ
easat-267	230	2	the	the	DET
easat-267	230	3	selection	selection	NOUN
easat-267	230	4	favors	favor	VERB
easat-267	230	5	the	the	DET
easat-267	230	6	mutation	mutation	NOUN
easat-267	230	7	with	with	ADP
easat-267	230	8	least	least	ADJ
easat-267	230	9	cost	cost	VERB
easat-267	230	10	to	to	ADP
easat-267	230	11	the	the	DET
easat-267	230	12	population	population	NOUN
easat-267	230	13	,	,	PUNCT
easat-267	230	14	as	as	SCONJ
easat-267	230	15	the	the	DET
easat-267	230	16	clinical	clinical	ADJ
easat-267	230	17	manifestations	manifestation	NOUN
easat-267	230	18	of	of	ADP
easat-267	230	19	g6pd	g6pd	NOUN
easat-267	230	20	deficiency	deficiency	NOUN
easat-267	230	21	are	be	AUX
easat-267	230	22	mild	mild	ADJ
easat-267	230	23	and	and	CCONJ
easat-267	230	24	do	do	AUX
easat-267	230	25	not	not	PART
easat-267	230	26	result	result	VERB
easat-267	230	27	in	in	ADP
easat-267	230	28	a	a	DET
easat-267	230	29	complete	complete	ADJ
easat-267	230	30	loss	loss	NOUN
easat-267	230	31	of	of	ADP
easat-267	230	32	enzyme	enzyme	NOUN
easat-267	230	33	activity	activity	NOUN
easat-267	230	34	against	against	ADP
easat-267	230	35	the	the	DET
easat-267	230	36	sickle	sickle	NOUN
easat-267	230	37	cell	cell	NOUN
easat-267	230	38	disease	disease	NOUN
easat-267	230	39	with	with	ADP
easat-267	230	40	high	high	ADJ
easat-267	230	41	morbidity	morbidity	NOUN
easat-267	230	42	and	and	CCONJ
easat-267	230	43	mortality	mortality	NOUN
easat-267	230	44	in	in	ADP
easat-267	230	45	the	the	DET
easat-267	230	46	region	region	NOUN
easat-267	230	47	.	.	PUNCT
easat-267	231	1	even	even	ADV
easat-267	231	2	though	though	SCONJ
easat-267	231	3	the	the	DET
easat-267	231	4	above	above	ADJ
easat-267	231	5	could	could	AUX
easat-267	231	6	explain	explain	VERB
easat-267	231	7	,	,	PUNCT
easat-267	231	8	why	why	SCONJ
easat-267	231	9	mutations	mutation	NOUN
easat-267	231	10	conferring	confer	VERB
easat-267	231	11	malaria	malaria	NOUN
easat-267	231	12	protection	protection	NOUN
easat-267	231	13	are	be	AUX
easat-267	231	14	highly	highly	ADV
easat-267	231	15	variable	variable	ADJ
easat-267	231	16	and	and	CCONJ
easat-267	231	17	maintained	maintain	VERB
easat-267	231	18	in	in	ADP
easat-267	231	19	the	the	DET
easat-267	231	20	population	population	NOUN
easat-267	231	21	,	,	PUNCT
easat-267	231	22	the	the	DET
easat-267	231	23	association	association	NOUN
easat-267	231	24	between	between	ADP
easat-267	231	25	sickle	sickle	NOUN
easat-267	231	26	cell	cell	NOUN
easat-267	231	27	disease	disease	NOUN
easat-267	231	28	and	and	CCONJ
easat-267	231	29	g6pd	g6pd	NOUN
easat-267	231	30	enzyme	enzyme	NOUN
easat-267	231	31	deficiency	deficiency	NOUN
easat-267	231	32	seems	seem	VERB
easat-267	231	33	to	to	PART
easat-267	231	34	be	be	AUX
easat-267	231	35	well	well	ADV
easat-267	231	36	-	-	PUNCT
easat-267	231	37	suited	suit	VERB
easat-267	231	38	here	here	ADV
easat-267	231	39	.	.	PUNCT
easat-267	232	1	thus	thus	ADV
easat-267	232	2	,	,	PUNCT
easat-267	232	3	the	the	DET
easat-267	232	4	protection	protection	NOUN
easat-267	232	5	is	be	AUX
easat-267	232	6	principally	principally	ADV
easat-267	232	7	present	present	ADJ
easat-267	232	8	for	for	ADP
easat-267	232	9	severe	severe	ADJ
easat-267	232	10	disease	disease	NOUN
easat-267	232	11	and	and	CCONJ
easat-267	232	12	largely	largely	ADV
easat-267	232	13	absent	absent	ADJ
easat-267	232	14	for	for	ADP
easat-267	232	15	plasmodium	plasmodium	NOUN
easat-267	232	16	falciparum	falciparum	ADJ
easat-267	232	17	infection	infection	NOUN
easat-267	232	18	,	,	PUNCT
easat-267	232	19	suggesting	suggest	VERB
easat-267	232	20	that	that	SCONJ
easat-267	232	21	hemoglobin	hemoglobin	NOUN
easat-267	232	22	disorders	disorder	NOUN
easat-267	232	23	specifically	specifically	ADV
easat-267	232	24	neutralize	neutralize	VERB
easat-267	232	25	the	the	DET
easat-267	232	26	parasite	parasite	NOUN
easat-267	232	27	's	's	PART
easat-267	232	28	in	in	ADP
easat-267	232	29	vivo	vivo	ADJ
easat-267	232	30	mechanisms	mechanism	NOUN
easat-267	232	31	of	of	ADP
easat-267	232	32	pathogenesis	pathogenesis	NOUN
easat-267	232	33	.	.	PUNCT
easat-267	233	1	these	these	DET
easat-267	233	2	genetic	genetic	ADJ
easat-267	233	3	traits	trait	NOUN
easat-267	233	4	-	-	PUNCT
easat-267	233	5	including	include	VERB
easat-267	233	6	hemoglobin	hemoglobin	NOUN
easat-267	233	7	c	c	PROPN
easat-267	233	8	(	(	PUNCT
easat-267	233	9	hb	hb	PROPN
easat-267	233	10	c	c	PROPN
easat-267	233	11	)	)	PUNCT
easat-267	233	12	,	,	PUNCT
easat-267	233	13	hemoglobin	hemoglobin	NOUN
easat-267	233	14	d	d	PROPN
easat-267	233	15	(	(	PUNCT
easat-267	233	16	hb	hb	X
easat-267	233	17	d	d	PROPN
easat-267	233	18	)	)	PUNCT
easat-267	233	19	,	,	PUNCT
easat-267	233	20	hemoglobin	hemoglobin	NOUN
easat-267	233	21	e	e	X
easat-267	233	22	(	(	PUNCT
easat-267	233	23	hb	hb	X
easat-267	233	24	e	e	PROPN
easat-267	233	25	)	)	PUNCT
easat-267	233	26	,	,	PUNCT
easat-267	233	27	hemoglobin	hemoglobin	NOUN
easat-267	233	28	s	s	PART
easat-267	233	29	(	(	PUNCT
easat-267	233	30	hb	hb	PROPN
easat-267	233	31	s	s	PART
easat-267	233	32	)	)	PUNCT
easat-267	233	33	and	and	CCONJ
easat-267	233	34	αand	αand	ADV
easat-267	233	35	β	β	NOUN
easat-267	233	36	-	-	PUNCT
easat-267	233	37	thalassemias	thalassemias	NOUN
easat-267	233	38	-	-	PUNCT
easat-267	233	39	are	be	AUX
easat-267	233	40	the	the	DET
easat-267	233	41	most	most	ADV
easat-267	233	42	common	common	ADJ
easat-267	233	43	monogenic	monogenic	ADJ
easat-267	233	44	human	human	ADJ
easat-267	233	45	disorders	disorder	NOUN
easat-267	233	46	and	and	CCONJ
easat-267	233	47	can	can	AUX
easat-267	233	48	confer	confer	VERB
easat-267	233	49	remarkable	remarkable	ADJ
easat-267	233	50	degrees	degree	NOUN
easat-267	233	51	of	of	ADP
easat-267	233	52	protection	protection	NOUN
easat-267	233	53	from	from	ADP
easat-267	233	54	severe	severe	ADJ
easat-267	233	55	,	,	PUNCT
easat-267	233	56	life	life	NOUN
easat-267	233	57	-	-	PUNCT
easat-267	233	58	threatening	threaten	VERB
easat-267	233	59	falciparum	falciparum	ADJ
easat-267	233	60	malaria	malaria	NOUN
easat-267	233	61	in	in	ADP
easat-267	233	62	african	african	ADJ
easat-267	233	63	children	child	NOUN
easat-267	233	64	:	:	PUNCT
easat-267	233	65	the	the	DET
easat-267	233	66	risk	risk	NOUN
easat-267	233	67	is	be	AUX
easat-267	233	68	reduced	reduce	VERB
easat-267	233	69	70	70	NUM
easat-267	233	70	%	%	NOUN
easat-267	233	71	by	by	ADP
easat-267	233	72	homozygous	homozygous	ADJ
easat-267	233	73	hb	hb	X
easat-267	233	74	c	c	PROPN
easat-267	233	75	and	and	CCONJ
easat-267	233	76	90	90	NUM
easat-267	233	77	%	%	NOUN
easat-267	233	78	by	by	ADP
easat-267	233	79	heterozygous	heterozygous	ADJ
easat-267	233	80	hb	hb	NOUN
easat-267	233	81	s	s	X
easat-267	233	82	(	(	PUNCT
easat-267	233	83	sickle	sickle	NOUN
easat-267	233	84	-	-	PUNCT
easat-267	233	85	cell	cell	NOUN
easat-267	233	86	trait	trait	NOUN
easat-267	233	87	)	)	PUNCT
easat-267	233	88	.	.	PUNCT
easat-267	234	1	these	these	DET
easat-267	234	2	hemoglobin	hemoglobin	NOUN
easat-267	234	3	variants	variant	NOUN
easat-267	234	4	thus	thus	ADV
easat-267	234	5	represent	represent	VERB
easat-267	234	6	a	a	DET
easat-267	234	7	“	"	PUNCT
easat-267	234	8	natural	natural	ADJ
easat-267	234	9	experiment	experiment	NOUN
easat-267	234	10	”	"	PUNCT
easat-267	234	11	to	to	PART
easat-267	234	12	identify	identify	VERB
easat-267	234	13	the	the	DET
easat-267	234	14	cellular	cellular	ADJ
easat-267	234	15	and	and	CCONJ
easat-267	234	16	molecular	molecular	ADJ
easat-267	234	17	mechanisms	mechanism	NOUN
easat-267	234	18	by	by	ADP
easat-267	234	19	which	which	PRON
easat-267	234	20	plasmodium	plasmodium	NOUN
easat-267	234	21	falciparum	falciparum	NOUN
easat-267	234	22	produces	produce	VERB
easat-267	234	23	clinical	clinical	ADJ
easat-267	234	24	morbidity	morbidity	NOUN
easat-267	234	25	,	,	PUNCT
easat-267	234	26	which	which	PRON
easat-267	234	27	remain	remain	VERB
easat-267	234	28	partially	partially	ADV
easat-267	234	29	obscured	obscure	VERB
easat-267	234	30	due	due	ADP
easat-267	234	31	to	to	ADP
easat-267	234	32	the	the	DET
easat-267	234	33	complexity	complexity	NOUN
easat-267	234	34	of	of	ADP
easat-267	234	35	interactions	interaction	NOUN
easat-267	234	36	between	between	ADP
easat-267	234	37	this	this	DET
easat-267	234	38	parasite	parasite	NOUN
easat-267	234	39	and	and	CCONJ
easat-267	234	40	its	its	PRON
easat-267	234	41	human	human	ADJ
easat-267	234	42	host	host	NOUN
easat-267	234	43	.	.	PUNCT
easat-267	235	1	multiple	multiple	ADJ
easat-267	235	2	lines	line	NOUN
easat-267	235	3	of	of	ADP
easat-267	235	4	evidence	evidence	NOUN
easat-267	235	5	support	support	VERB
easat-267	235	6	a	a	DET
easat-267	235	7	restriction	restriction	NOUN
easat-267	235	8	of	of	ADP
easat-267	235	9	parasite	parasite	ADJ
easat-267	235	10	growth	growth	NOUN
easat-267	235	11	by	by	ADP
easat-267	235	12	various	various	ADJ
easat-267	235	13	hemoglobinopathies	hemoglobinopathy	NOUN
easat-267	235	14	,	,	PUNCT
easat-267	235	15	and	and	CCONJ
easat-267	235	16	recent	recent	ADJ
easat-267	235	17	data	datum	NOUN
easat-267	235	18	suggest	suggest	VERB
easat-267	235	19	this	this	DET
easat-267	235	20	phenomenon	phenomenon	NOUN
easat-267	235	21	may	may	AUX
easat-267	235	22	result	result	VERB
easat-267	235	23	from	from	ADP
easat-267	235	24	host	host	NOUN
easat-267	235	25	micro	micro	PROPN
easat-267	235	26	rna	rna	PROPN
easat-267	235	27	interference	interference	NOUN
easat-267	235	28	with	with	ADP
easat-267	235	29	parasite	parasite	ADJ
easat-267	235	30	metabolism	metabolism	NOUN
easat-267	235	31	.	.	PUNCT
easat-267	236	1	therefore	therefore	ADV
easat-267	236	2	,	,	PUNCT
easat-267	236	3	owing	owe	VERB
easat-267	236	4	to	to	ADP
easat-267	236	5	the	the	DET
easat-267	236	6	co	co	NOUN
easat-267	236	7	-	-	NOUN
easat-267	236	8	evolution	evolution	NOUN
easat-267	236	9	of	of	ADP
easat-267	236	10	humans	human	NOUN
easat-267	236	11	and	and	CCONJ
easat-267	236	12	plasmodium	plasmodium	NOUN
easat-267	236	13	falciparum	falciparum	ADJ
easat-267	236	14	parasites	parasite	NOUN
easat-267	236	15	,	,	PUNCT
easat-267	236	16	the	the	DET
easat-267	236	17	human	human	ADJ
easat-267	236	18	genome	genome	NOUN
easat-267	236	19	is	be	AUX
easat-267	236	20	imprinted	imprint	VERB
easat-267	236	21	with	with	ADP
easat-267	236	22	polymorphisms	polymorphism	NOUN
easat-267	236	23	that	that	PRON
easat-267	236	24	not	not	PART
easat-267	236	25	only	only	ADV
easat-267	236	26	confer	confer	VERB
easat-267	236	27	innate	innate	ADJ
easat-267	236	28	resistance	resistance	NOUN
easat-267	236	29	to	to	ADP
easat-267	236	30	falciparum	falciparum	ADJ
easat-267	236	31	malaria	malaria	NOUN
easat-267	236	32	,	,	PUNCT
easat-267	236	33	but	but	CCONJ
easat-267	236	34	also	also	ADV
easat-267	236	35	cause	cause	VERB
easat-267	236	36	hemoglobinopathies	hemoglobinopathy	NOUN
easat-267	236	37	to	to	PART
easat-267	236	38	counter	counter	VERB
easat-267	236	39	the	the	DET
easat-267	236	40	adverse	adverse	ADJ
easat-267	236	41	effects	effect	NOUN
easat-267	236	42	of	of	ADP
easat-267	236	43	severe	severe	ADJ
easat-267	236	44	malaria	malaria	NOUN
easat-267	236	45	.	.	PUNCT
easat-267	237	1	acknowledgements	acknowledgement	VERB
easat-267	237	2	the	the	DET
easat-267	237	3	author	author	NOUN
easat-267	237	4	gratefully	gratefully	ADV
easat-267	237	5	acknowledges	acknowledge	VERB
easat-267	237	6	all	all	DET
easat-267	237	7	the	the	DET
easat-267	237	8	researchers	researcher	NOUN
easat-267	237	9	,	,	PUNCT
easat-267	237	10	investigators	investigator	NOUN
easat-267	237	11	and	and	CCONJ
easat-267	237	12	authors	author	NOUN
easat-267	237	13	whose	whose	DET
easat-267	237	14	works	work	NOUN
easat-267	237	15	have	have	AUX
easat-267	237	16	been	be	AUX
easat-267	237	17	quoted	quote	VERB
easat-267	237	18	directly	directly	ADV
easat-267	237	19	or	or	CCONJ
easat-267	237	20	indirectly	indirectly	ADV
easat-267	237	21	in	in	ADP
easat-267	237	22	this	this	DET
easat-267	237	23	write	write	NOUN
easat-267	237	24	up	up	ADP
easat-267	237	25	to	to	PART
easat-267	237	26	explain	explain	VERB
easat-267	237	27	or	or	CCONJ
easat-267	237	28	interpret	interpret	VERB
easat-267	237	29	the	the	DET
easat-267	237	30	findings	finding	NOUN
easat-267	237	31	logically	logically	ADV
easat-267	237	32	to	to	PART
easat-267	237	33	make	make	VERB
easat-267	237	34	it	it	PRON
easat-267	237	35	understandable	understandable	ADJ
easat-267	237	36	.	.	PUNCT
easat-267	238	1	51	51	NUM
easat-267	238	2	edelweiss	edelweiss	PROPN
easat-267	238	3	applied	apply	VERB
easat-267	238	4	science	science	NOUN
easat-267	238	5	and	and	CCONJ
easat-267	238	6	technology	technology	NOUN
easat-267	238	7	issn	issn	PROPN
easat-267	238	8	:	:	PUNCT
easat-267	238	9	2576	2576	NUM
easat-267	238	10	-	-	SYM
easat-267	238	11	8484	8484	NUM
easat-267	238	12	vol	vol	NOUN
easat-267	238	13	.	.	PROPN
easat-267	239	1	3	3	NUM
easat-267	239	2	,	,	PUNCT
easat-267	239	3	no	no	INTJ
easat-267	239	4	.	.	NOUN
easat-267	239	5	1	1	NUM
easat-267	239	6	:	:	SYM
easat-267	239	7	44	44	NUM
easat-267	239	8	-	-	SYM
easat-267	239	9	52	52	NUM
easat-267	239	10	,	,	PUNCT
easat-267	239	11	2019	2019	NUM
easat-267	239	12	doi	doi	NOUN
easat-267	239	13	:	:	PUNCT
easat-267	239	14	10.33805/2576	10.33805/2576	NUM
easat-267	239	15	-	-	SYM
easat-267	239	16	8484.167	8484.167	NUM
easat-267	239	17	©	©	PROPN
easat-267	239	18	2019	2019	NUM
easat-267	239	19	by	by	ADP
easat-267	239	20	the	the	DET
easat-267	239	21	author	author	NOUN
easat-267	239	22	abbreviations	abbreviation	NOUN
easat-267	239	23	:	:	PUNCT
easat-267	239	24	sca	sca	ADJ
easat-267	239	25	-	-	PUNCT
easat-267	239	26	sickle	sickle	PROPN
easat-267	239	27	cell	cell	NOUN
easat-267	239	28	anemia	anemia	NOUN
easat-267	239	29	,	,	PUNCT
easat-267	239	30	g6dp	g6dp	PROPN
easat-267	239	31	-	-	PUNCT
easat-267	239	32	glucose-6	glucose-6	NOUN
easat-267	239	33	-	-	PUNCT
easat-267	239	34	phosphate	phosphate	NOUN
easat-267	239	35	dehydrogenase	dehydrogenase	NOUN
easat-267	239	36	,	,	PUNCT
easat-267	239	37	nsaids	nsaid	NOUN
easat-267	239	38	-	-	PUNCT
easat-267	239	39	nonsteroidal	nonsteroidal	NOUN
easat-267	239	40	antiinflammatory	antiinflammatory	NOUN
easat-267	239	41	medications	medication	NOUN
easat-267	239	42	.	.	PUNCT
easat-267	240	1	references	reference	NOUN
easat-267	240	2	[	[	X
easat-267	240	3	1	1	NUM
easat-267	240	4	]	]	PUNCT
easat-267	240	5	r.	r.	PROPN
easat-267	240	6	balgir	balgir	PROPN
easat-267	240	7	,	,	PUNCT
easat-267	240	8	"	"	PUNCT
easat-267	240	9	do	do	AUX
easat-267	240	10	tribal	tribal	ADJ
easat-267	240	11	communities	community	NOUN
easat-267	240	12	show	show	VERB
easat-267	240	13	inverse	inverse	NOUN
easat-267	240	14	relationship	relationship	NOUN
easat-267	240	15	between	between	ADP
easat-267	240	16	sickle	sickle	NOUN
easat-267	240	17	cell	cell	NOUN
easat-267	240	18	disorders	disorder	NOUN
easat-267	240	19	and	and	CCONJ
easat-267	240	20	glucose-6	glucose-6	NOUN
easat-267	240	21	-	-	PUNCT
easat-267	240	22	phosphate	phosphate	NOUN
easat-267	240	23	dehydrogenase	dehydrogenase	NOUN
easat-267	240	24	deficiency	deficiency	NOUN
easat-267	240	25	in	in	ADP
easat-267	240	26	malaria	malaria	ADJ
easat-267	240	27	endemic	endemic	ADJ
easat-267	240	28	areas	area	NOUN
easat-267	240	29	of	of	ADP
easat-267	240	30	central	central	ADJ
easat-267	240	31	-	-	PUNCT
easat-267	240	32	eastern	eastern	ADJ
easat-267	240	33	india	india	PROPN
easat-267	240	34	?	?	PUNCT
easat-267	240	35	,	,	PUNCT
easat-267	241	1	"	"	PUNCT
easat-267	241	2	homo	homo	PROPN
easat-267	241	3	j	j	PROPN
easat-267	241	4	compar	compar	PROPN
easat-267	241	5	hum	hum	PROPN
easat-267	241	6	biol	biol	PROPN
easat-267	241	7	,	,	PUNCT
easat-267	241	8	vol	vol	NOUN
easat-267	241	9	.	.	PROPN
easat-267	241	10	57	57	NUM
easat-267	241	11	,	,	PUNCT
easat-267	241	12	pp	pp	ADJ
easat-267	241	13	.	.	PUNCT
easat-267	242	1	163	163	NUM
easat-267	242	2	-	-	SYM
easat-267	242	3	176	176	NUM
easat-267	242	4	,	,	PUNCT
easat-267	242	5	2006	2006	NUM
easat-267	242	6	.	.	PUNCT
easat-267	243	1	https://doi.org/10.1016/j.jchb.2006.01.003	https://doi.org/10.1016/j.jchb.2006.01.003	NOUN
easat-267	243	2	[	[	X
easat-267	243	3	2	2	NUM
easat-267	243	4	]	]	PUNCT
easat-267	243	5	r.	r.	PROPN
easat-267	243	6	balgir	balgir	PROPN
easat-267	243	7	,	,	PUNCT
easat-267	243	8	"	"	PUNCT
easat-267	243	9	community	community	NOUN
easat-267	243	10	expansion	expansion	NOUN
easat-267	243	11	and	and	CCONJ
easat-267	243	12	gene	gene	NOUN
easat-267	243	13	geography	geography	NOUN
easat-267	243	14	of	of	ADP
easat-267	243	15	sickle	sickle	NOUN
easat-267	243	16	cell	cell	NOUN
easat-267	243	17	trait	trait	NOUN
easat-267	243	18	and	and	CCONJ
easat-267	243	19	g6pd	g6pd	NOUN
easat-267	243	20	deficiency	deficiency	NOUN
easat-267	243	21	,	,	PUNCT
easat-267	243	22	and	and	CCONJ
easat-267	243	23	natural	natural	ADJ
easat-267	243	24	selection	selection	NOUN
easat-267	243	25	against	against	ADP
easat-267	243	26	malaria	malaria	NOUN
easat-267	243	27	:	:	PUNCT
easat-267	243	28	experience	experience	NOUN
easat-267	243	29	from	from	ADP
easat-267	243	30	tribal	tribal	ADJ
easat-267	243	31	land	land	NOUN
easat-267	243	32	of	of	ADP
easat-267	243	33	india	india	PROPN
easat-267	243	34	,	,	PUNCT
easat-267	243	35	"	"	PUNCT
easat-267	243	36	cardiovasc	cardiovasc	PROPN
easat-267	243	37	hematol	hematol	PROPN
easat-267	243	38	agents	agent	NOUN
easat-267	243	39	med	me	VERB
easat-267	243	40	chem	chem	NOUN
easat-267	243	41	,	,	PUNCT
easat-267	243	42	vol	vol	NOUN
easat-267	243	43	.	.	PROPN
easat-267	243	44	10	10	NUM
easat-267	243	45	,	,	PUNCT
easat-267	243	46	pp	pp	ADJ
easat-267	243	47	.	.	PUNCT
easat-267	244	1	3	3	NUM
easat-267	244	2	-	-	SYM
easat-267	244	3	13	13	NUM
easat-267	244	4	,	,	PUNCT
easat-267	244	5	2012	2012	NUM
easat-267	244	6	.	.	PUNCT
easat-267	245	1	https://doi.org/10.2174/187152512799201190	https://doi.org/10.2174/187152512799201190	PROPN
easat-267	246	1	[	[	X
easat-267	246	2	3	3	X
easat-267	246	3	]	]	PUNCT
easat-267	246	4	world	world	NOUN
easat-267	246	5	malaria	malaria	NOUN
easat-267	246	6	report	report	NOUN
easat-267	246	7	,	,	PUNCT
easat-267	246	8	"	"	PUNCT
easat-267	246	9	who	who	PRON
easat-267	246	10	key	key	ADJ
easat-267	246	11	points	point	NOUN
easat-267	246	12	,	,	PUNCT
easat-267	246	13	"	"	PUNCT
easat-267	246	14	2017	2017	NUM
easat-267	246	15	.	.	PUNCT
easat-267	247	1	[	[	X
easat-267	247	2	4	4	X
easat-267	247	3	]	]	PUNCT
easat-267	247	4	j.	j.	PROPN
easat-267	247	5	haldane	haldane	PROPN
easat-267	247	6	,	,	PUNCT
easat-267	247	7	"	"	PUNCT
easat-267	247	8	disease	disease	NOUN
easat-267	247	9	and	and	CCONJ
easat-267	247	10	evolution	evolution	NOUN
easat-267	247	11	,	,	PUNCT
easat-267	247	12	"	"	PUNCT
easat-267	247	13	scientia	scientia	PROPN
easat-267	247	14	ricerca	ricerca	PROPN
easat-267	247	15	,	,	PUNCT
easat-267	247	16	vol	vol	NOUN
easat-267	247	17	.	.	PROPN
easat-267	248	1	119	119	NUM
easat-267	248	2	,	,	PUNCT
easat-267	248	3	pp	pp	ADJ
easat-267	248	4	.	.	PUNCT
easat-267	249	1	68	68	NUM
easat-267	249	2	-	-	SYM
easat-267	249	3	76	76	NUM
easat-267	249	4	,	,	PUNCT
easat-267	249	5	1949	1949	NUM
easat-267	249	6	.	.	PUNCT
easat-267	250	1	[	[	X
easat-267	250	2	5	5	NUM
easat-267	250	3	]	]	PUNCT
easat-267	250	4	r.	r.	PROPN
easat-267	250	5	balgir	balgir	PROPN
easat-267	250	6	,	,	PUNCT
easat-267	250	7	"	"	PUNCT
easat-267	250	8	serogenetc	serogenetc	ADJ
easat-267	250	9	studies	study	NOUN
easat-267	250	10	in	in	ADP
easat-267	250	11	the	the	DET
easat-267	250	12	gypsy	gypsy	NOUN
easat-267	250	13	sikligars	sikligar	NOUN
easat-267	250	14	of	of	ADP
easat-267	250	15	north	north	ADJ
easat-267	250	16	western	western	PROPN
easat-267	250	17	india	india	PROPN
easat-267	250	18	,	,	PUNCT
easat-267	250	19	"	"	PUNCT
easat-267	250	20	hum	hum	ADJ
easat-267	250	21	biol	biol	PROPN
easat-267	250	22	,	,	PUNCT
easat-267	250	23	vol	vol	NOUN
easat-267	250	24	.	.	PROPN
easat-267	250	25	58	58	NUM
easat-267	250	26	,	,	PUNCT
easat-267	250	27	pp	pp	ADJ
easat-267	250	28	.	.	PUNCT
easat-267	251	1	171	171	NUM
easat-267	251	2	-	-	SYM
easat-267	251	3	187	187	NUM
easat-267	251	4	,	,	PUNCT
easat-267	251	5	1986	1986	NUM
easat-267	251	6	.	.	PUNCT
easat-267	252	1	[	[	X
easat-267	252	2	6	6	NUM
easat-267	252	3	]	]	X
easat-267	252	4	r.	r.	PROPN
easat-267	252	5	balgir	balgir	PROPN
easat-267	252	6	and	and	CCONJ
easat-267	252	7	j.	j.	PROPN
easat-267	252	8	sharma	sharma	PROPN
easat-267	252	9	,	,	PUNCT
easat-267	252	10	"	"	PUNCT
easat-267	252	11	genetic	genetic	ADJ
easat-267	252	12	markers	marker	NOUN
easat-267	252	13	in	in	ADP
easat-267	252	14	the	the	DET
easat-267	252	15	hindu	hindu	NOUN
easat-267	252	16	and	and	CCONJ
easat-267	252	17	muslim	muslim	ADJ
easat-267	252	18	gujjars	gujjar	NOUN
easat-267	252	19	of	of	ADP
easat-267	252	20	north	north	NOUN
easat-267	252	21	-	-	PUNCT
easat-267	252	22	western	western	ADJ
easat-267	252	23	india	india	PROPN
easat-267	252	24	"	"	PUNCT
easat-267	252	25	am	be	AUX
easat-267	252	26	j	j	PROPN
easat-267	252	27	phys	phy	NOUN
easat-267	252	28	anthropol	anthropol	NOUN
easat-267	252	29	,	,	PUNCT
easat-267	252	30	vol	vol	NOUN
easat-267	252	31	.	.	PROPN
easat-267	253	1	75	75	NUM
easat-267	253	2	,	,	PUNCT
easat-267	253	3	pp	pp	ADJ
easat-267	253	4	.	.	PUNCT
easat-267	254	1	391	391	NUM
easat-267	254	2	-	-	SYM
easat-267	254	3	403	403	NUM
easat-267	254	4	,	,	PUNCT
easat-267	254	5	1988	1988	NUM
easat-267	254	6	.	.	PUNCT
easat-267	255	1	https://doi.org/10.1002/ajpa.1330750310	https://doi.org/10.1002/ajpa.1330750310	X
easat-267	256	1	[	[	X
easat-267	256	2	7	7	NUM
easat-267	256	3	]	]	X
easat-267	256	4	r.	r.	PROPN
easat-267	256	5	balgir	balgir	PROPN
easat-267	256	6	,	,	PUNCT
easat-267	256	7	b.	b.	NOUN
easat-267	256	8	dash	dash	NOUN
easat-267	256	9	,	,	PUNCT
easat-267	256	10	and	and	CCONJ
easat-267	256	11	b.	b.	PROPN
easat-267	256	12	murmu	murmu	PROPN
easat-267	256	13	,	,	PUNCT
easat-267	256	14	"	"	PUNCT
easat-267	256	15	blood	blood	NOUN
easat-267	256	16	groups	group	NOUN
easat-267	256	17	,	,	PUNCT
easat-267	256	18	hemoglobinopathy	hemoglobinopathy	ADJ
easat-267	256	19	and	and	CCONJ
easat-267	256	20	g-6	g-6	NOUN
easat-267	256	21	-	-	PUNCT
easat-267	256	22	pd	pd	NOUN
easat-267	256	23	deficiency	deficiency	NOUN
easat-267	256	24	investigations	investigation	NOUN
easat-267	256	25	among	among	ADP
easat-267	256	26	fifteen	fifteen	NUM
easat-267	256	27	major	major	ADJ
easat-267	256	28	scheduled	schedule	VERB
easat-267	256	29	tribes	tribe	NOUN
easat-267	256	30	of	of	ADP
easat-267	256	31	orissa	orissa	PROPN
easat-267	256	32	,	,	PUNCT
easat-267	256	33	india	india	PROPN
easat-267	256	34	,	,	PUNCT
easat-267	256	35	"	"	PUNCT
easat-267	256	36	anthropologist	anthropologist	NOUN
easat-267	256	37	,	,	PUNCT
easat-267	256	38	vol	vol	NOUN
easat-267	256	39	.	.	PROPN
easat-267	256	40	6	6	NUM
easat-267	256	41	,	,	PUNCT
easat-267	256	42	pp	pp	ADJ
easat-267	256	43	.	.	PUNCT
easat-267	257	1	69	69	NUM
easat-267	257	2	-	-	SYM
easat-267	257	3	75	75	NUM
easat-267	257	4	,	,	PUNCT
easat-267	257	5	2004	2004	NUM
easat-267	257	6	.	.	PUNCT
easat-267	258	1	https://doi.org/10.1080/09720073.2004.11890830	https://doi.org/10.1080/09720073.2004.11890830	PUNCT
easat-267	259	1	[	[	X
easat-267	259	2	8	8	NUM
easat-267	259	3	]	]	X
easat-267	259	4	r.	r.	PROPN
easat-267	259	5	balgir	balgir	PROPN
easat-267	259	6	,	,	PUNCT
easat-267	259	7	"	"	PUNCT
easat-267	259	8	the	the	DET
easat-267	259	9	spectrum	spectrum	NOUN
easat-267	259	10	of	of	ADP
easat-267	259	11	hemoglobin	hemoglobin	NOUN
easat-267	259	12	variants	variant	NOUN
easat-267	259	13	in	in	ADP
easat-267	259	14	two	two	NUM
easat-267	259	15	scheduled	schedule	VERB
easat-267	259	16	tribes	tribe	NOUN
easat-267	259	17	of	of	ADP
easat-267	259	18	sundargarh	sundargarh	NOUN
easat-267	259	19	district	district	NOUN
easat-267	259	20	in	in	ADP
easat-267	259	21	north	north	NOUN
easat-267	259	22	-	-	PUNCT
easat-267	259	23	western	western	PROPN
easat-267	259	24	orissa	orissa	PROPN
easat-267	259	25	,	,	PUNCT
easat-267	259	26	india	india	PROPN
easat-267	259	27	,	,	PUNCT
easat-267	259	28	"	"	PUNCT
easat-267	259	29	ann	ann	PROPN
easat-267	259	30	hum	hum	PROPN
easat-267	259	31	biol	biol	PROPN
easat-267	259	32	,	,	PUNCT
easat-267	259	33	vol	vol	NOUN
easat-267	259	34	.	.	PROPN
easat-267	259	35	32	32	NUM
easat-267	259	36	,	,	PUNCT
easat-267	259	37	pp	pp	ADJ
easat-267	259	38	.	.	PUNCT
easat-267	260	1	560	560	NUM
easat-267	260	2	-	-	SYM
easat-267	260	3	573	573	NUM
easat-267	260	4	,	,	PUNCT
easat-267	260	5	2005	2005	NUM
easat-267	260	6	.	.	PUNCT
easat-267	261	1	https://doi.org/10.1080/03014460500228741	https://doi.org/10.1080/03014460500228741	X
easat-267	262	1	[	[	X
easat-267	262	2	9	9	NUM
easat-267	262	3	]	]	X
easat-267	262	4	r.	r.	PROPN
easat-267	262	5	balgir	balgir	PROPN
easat-267	262	6	,	,	PUNCT
easat-267	262	7	"	"	PUNCT
easat-267	262	8	genetic	genetic	ADJ
easat-267	262	9	burden	burden	NOUN
easat-267	262	10	of	of	ADP
easat-267	262	11	red	red	ADJ
easat-267	262	12	cell	cell	NOUN
easat-267	262	13	enzyme	enzyme	NOUN
easat-267	262	14	glucose-6	glucose-6	NOUN
easat-267	262	15	-	-	PUNCT
easat-267	262	16	phosphate	phosphate	NOUN
easat-267	262	17	dehydrogenase	dehydrogenase	NOUN
easat-267	262	18	deficiency	deficiency	NOUN
easat-267	262	19	in	in	ADP
easat-267	262	20	two	two	NUM
easat-267	262	21	major	major	ADJ
easat-267	262	22	scheduled	schedule	VERB
easat-267	262	23	tribes	tribe	NOUN
easat-267	262	24	of	of	ADP
easat-267	262	25	sundargarh	sundargarh	NOUN
easat-267	262	26	district	district	NOUN
easat-267	262	27	in	in	ADP
easat-267	262	28	north	north	NOUN
easat-267	262	29	-	-	PUNCT
easat-267	262	30	western	western	NOUN
easat-267	262	31	orissa	orissa	PROPN
easat-267	262	32	,	,	PUNCT
easat-267	262	33	"	"	PUNCT
easat-267	262	34	current	current	ADJ
easat-267	262	35	science	science	NOUN
easat-267	262	36	,	,	PUNCT
easat-267	262	37	vol	vol	NOUN
easat-267	262	38	.	.	PROPN
easat-267	262	39	92	92	NUM
easat-267	262	40	,	,	PUNCT
easat-267	262	41	pp	pp	ADJ
easat-267	262	42	.	.	PUNCT
easat-267	263	1	768	768	NUM
easat-267	263	2	-	-	SYM
easat-267	263	3	774	774	NUM
easat-267	263	4	,	,	PUNCT
easat-267	263	5	2007	2007	NUM
easat-267	263	6	.	.	PUNCT
easat-267	264	1	https://doi.org/10.1080/03014460500228741	https://doi.org/10.1080/03014460500228741	NOUN
easat-267	265	1	[	[	X
easat-267	265	2	10	10	NUM
easat-267	265	3	]	]	X
easat-267	265	4	r.	r.	PROPN
easat-267	265	5	balgir	balgir	PROPN
easat-267	265	6	,	,	PUNCT
easat-267	265	7	"	"	PUNCT
easat-267	265	8	genetic	genetic	ADJ
easat-267	265	9	diversity	diversity	NOUN
easat-267	265	10	of	of	ADP
easat-267	265	11	hemoglobinopathies	hemoglobinopathy	NOUN
easat-267	265	12	,	,	PUNCT
easat-267	265	13	g6pd	g6pd	NOUN
easat-267	265	14	deficiency	deficiency	NOUN
easat-267	265	15	and	and	CCONJ
easat-267	265	16	abo	abo	NOUN
easat-267	265	17	and	and	CCONJ
easat-267	265	18	rhesus	rhesus	NOUN
easat-267	265	19	blood	blood	NOUN
easat-267	265	20	groups	group	NOUN
easat-267	265	21	in	in	ADP
easat-267	265	22	two	two	NUM
easat-267	265	23	isolates	isolate	NOUN
easat-267	265	24	of	of	ADP
easat-267	265	25	primitive	primitive	ADJ
easat-267	265	26	kharia	kharia	NOUN
easat-267	265	27	tribe	tribe	NOUN
easat-267	265	28	in	in	ADP
easat-267	265	29	sundargarh	sundargarh	NOUN
easat-267	265	30	district	district	NOUN
easat-267	265	31	of	of	ADP
easat-267	265	32	north	north	NOUN
easat-267	265	33	-	-	PUNCT
easat-267	265	34	western	western	NOUN
easat-267	265	35	orissa	orissa	PROPN
easat-267	265	36	,	,	PUNCT
easat-267	265	37	india	india	PROPN
easat-267	265	38	,	,	PUNCT
easat-267	265	39	"	"	PUNCT
easat-267	265	40	journal	journal	NOUN
easat-267	265	41	of	of	ADP
easat-267	265	42	community	community	NOUN
easat-267	265	43	genetics	genetic	NOUN
easat-267	265	44	,	,	PUNCT
easat-267	265	45	vol	vol	NOUN
easat-267	265	46	.	.	PROPN
easat-267	265	47	1	1	NUM
easat-267	265	48	,	,	PUNCT
easat-267	265	49	pp	pp	ADJ
easat-267	265	50	.	.	PUNCT
easat-267	266	1	117	117	NUM
easat-267	266	2	-	-	SYM
easat-267	266	3	123	123	NUM
easat-267	266	4	,	,	PUNCT
easat-267	266	5	2010	2010	NUM
easat-267	266	6	.	.	PUNCT
easat-267	267	1	https://doi.org/10.1007/s12687-010-0016-y	https://doi.org/10.1007/s12687-010-0016-y	PROPN
easat-267	268	1	[	[	X
easat-267	268	2	11	11	NUM
easat-267	268	3	]	]	PUNCT
easat-267	268	4	t.	t.	PROPN
easat-267	268	5	millimono	millimono	PROPN
easat-267	268	6	,	,	PUNCT
easat-267	268	7	k.	k.	PROPN
easat-267	268	8	loua	loua	PROPN
easat-267	268	9	,	,	PUNCT
easat-267	268	10	s.	s.	PROPN
easat-267	268	11	rath	rath	PROPN
easat-267	268	12	,	,	PUNCT
easat-267	268	13	l.	l.	PROPN
easat-267	268	14	relvas	relvas	PROPN
easat-267	268	15	,	,	PUNCT
easat-267	268	16	and	and	CCONJ
easat-267	268	17	c.	c.	PROPN
easat-267	268	18	bento	bento	NOUN
easat-267	268	19	,	,	PUNCT
easat-267	268	20	"	"	PUNCT
easat-267	268	21	high	high	ADJ
easat-267	268	22	prevalence	prevalence	NOUN
easat-267	268	23	of	of	ADP
easat-267	268	24	hemoglobin	hemoglobin	NOUN
easat-267	268	25	disorders	disorder	NOUN
easat-267	268	26	and	and	CCONJ
easat-267	268	27	glucose-6phosphate	glucose-6phosphate	ADJ
easat-267	268	28	dehydrogenase	dehydrogenase	NOUN
easat-267	268	29	(	(	PUNCT
easat-267	268	30	g6pd	g6pd	NOUN
easat-267	268	31	)	)	PUNCT
easat-267	268	32	deficiency	deficiency	NOUN
easat-267	268	33	in	in	ADP
easat-267	268	34	the	the	DET
easat-267	268	35	republic	republic	NOUN
easat-267	268	36	of	of	ADP
easat-267	268	37	guinea	guinea	PROPN
easat-267	268	38	(	(	PUNCT
easat-267	268	39	west	west	PROPN
easat-267	268	40	africa	africa	PROPN
easat-267	268	41	)	)	PUNCT
easat-267	268	42	,	,	PUNCT
easat-267	268	43	"	"	PUNCT
easat-267	268	44	hemoglobin	hemoglobin	NOUN
easat-267	268	45	,	,	PUNCT
easat-267	268	46	vol	vol	NOUN
easat-267	268	47	.	.	PROPN
easat-267	268	48	36	36	NUM
easat-267	268	49	,	,	PUNCT
easat-267	268	50	pp	pp	ADJ
easat-267	268	51	.	.	PUNCT
easat-267	269	1	25	25	NUM
easat-267	269	2	-	-	SYM
easat-267	269	3	37	37	NUM
easat-267	269	4	,	,	PUNCT
easat-267	269	5	2012	2012	NUM
easat-267	269	6	.	.	PUNCT
easat-267	270	1	https://doi.org/10.3109/03630269.2011.600491	https://doi.org/10.3109/03630269.2011.600491	NOUN
easat-267	271	1	[	[	X
easat-267	271	2	12	12	NUM
easat-267	271	3	]	]	X
easat-267	271	4	r.	r.	PROPN
easat-267	271	5	balgir	balgir	PROPN
easat-267	271	6	,	,	PUNCT
easat-267	271	7	"	"	PUNCT
easat-267	271	8	spectrum	spectrum	NOUN
easat-267	271	9	of	of	ADP
easat-267	271	10	hemoglobinopathies	hemoglobinopathy	NOUN
easat-267	271	11	and	and	CCONJ
easat-267	271	12	evaluation	evaluation	NOUN
easat-267	271	13	of	of	ADP
easat-267	271	14	prevalence	prevalence	NOUN
easat-267	271	15	of	of	ADP
easat-267	271	16	beta	beta	NOUN
easat-267	271	17	-	-	PUNCT
easat-267	271	18	thalassemia	thalassemia	NOUN
easat-267	271	19	trait	trait	NOUN
easat-267	271	20	in	in	ADP
easat-267	271	21	the	the	DET
easat-267	271	22	tribal	tribal	ADJ
easat-267	271	23	land	land	NOUN
easat-267	271	24	of	of	ADP
easat-267	271	25	middle	middle	PROPN
easat-267	271	26	india	india	PROPN
easat-267	271	27	,	,	PUNCT
easat-267	271	28	"	"	PUNCT
easat-267	271	29	international	international	ADJ
easat-267	271	30	journal	journal	NOUN
easat-267	271	31	of	of	ADP
easat-267	271	32	public	public	ADJ
easat-267	271	33	health	health	NOUN
easat-267	271	34	,	,	PUNCT
easat-267	271	35	vol	vol	NOUN
easat-267	271	36	.	.	PROPN
easat-267	271	37	5	5	NUM
easat-267	271	38	,	,	PUNCT
easat-267	271	39	pp	pp	ADJ
easat-267	271	40	.	.	PUNCT
easat-267	272	1	165	165	NUM
easat-267	272	2	-	-	SYM
easat-267	272	3	177	177	NUM
easat-267	272	4	,	,	PUNCT
easat-267	272	5	2013	2013	NUM
easat-267	272	6	.	.	PUNCT
easat-267	273	1	[	[	X
easat-267	273	2	13	13	NUM
easat-267	273	3	]	]	PUNCT
easat-267	273	4	j.	j.	PROPN
easat-267	273	5	haldane	haldane	PROPN
easat-267	273	6	,	,	PUNCT
easat-267	273	7	the	the	DET
easat-267	273	8	causes	cause	NOUN
easat-267	273	9	of	of	ADP
easat-267	273	10	evolution	evolution	NOUN
easat-267	273	11	.	.	PUNCT
easat-267	274	1	uk	uk	PROPN
easat-267	274	2	:	:	PUNCT
easat-267	274	3	cambridge	cambridge	PROPN
easat-267	274	4	university	university	PROPN
easat-267	274	5	press	press	NOUN
easat-267	274	6	,	,	PUNCT
easat-267	274	7	1932	1932	NUM
easat-267	274	8	.	.	PUNCT
easat-267	275	1	[	[	X
easat-267	275	2	14	14	NUM
easat-267	275	3	]	]	X
easat-267	275	4	l.	l.	PROPN
easat-267	275	5	luzzatto	luzzatto	PROPN
easat-267	275	6	,	,	PUNCT
easat-267	275	7	"	"	PUNCT
easat-267	275	8	sickle	sickle	NOUN
easat-267	275	9	cell	cell	NOUN
easat-267	275	10	anaemia	anaemia	NOUN
easat-267	275	11	and	and	CCONJ
easat-267	275	12	malaria	malaria	NOUN
easat-267	275	13	,	,	PUNCT
easat-267	275	14	"	"	PUNCT
easat-267	275	15	mediterranean	mediterranean	PROPN
easat-267	275	16	journal	journal	PROPN
easat-267	275	17	of	of	ADP
easat-267	275	18	hematology	hematology	NOUN
easat-267	275	19	and	and	CCONJ
easat-267	275	20	infectious	infectious	ADJ
easat-267	275	21	diseases	disease	NOUN
easat-267	275	22	,	,	PUNCT
easat-267	275	23	vol	vol	NOUN
easat-267	275	24	.	.	PROPN
easat-267	275	25	4	4	NUM
easat-267	275	26	,	,	PUNCT
easat-267	275	27	p.	p.	NOUN
easat-267	275	28	e2012065	e2012065	PROPN
easat-267	275	29	,	,	PUNCT
easat-267	275	30	2012	2012	NUM
easat-267	275	31	.	.	PUNCT
easat-267	276	1	https://doi.org/10.4084/mjhid.2012.065	https://doi.org/10.4084/mjhid.2012.065	PROPN
easat-267	277	1	[	[	X
easat-267	277	2	15	15	NUM
easat-267	277	3	]	]	X
easat-267	277	4	d.	d.	PROPN
easat-267	277	5	kwiatkowski	kwiatkowski	PROPN
easat-267	277	6	,	,	PUNCT
easat-267	277	7	"	"	PUNCT
easat-267	277	8	how	how	SCONJ
easat-267	277	9	malaria	malaria	NOUN
easat-267	277	10	has	have	AUX
easat-267	277	11	affected	affect	VERB
easat-267	277	12	the	the	DET
easat-267	277	13	human	human	ADJ
easat-267	277	14	genome	genome	NOUN
easat-267	277	15	and	and	CCONJ
easat-267	277	16	what	what	PRON
easat-267	277	17	human	human	ADJ
easat-267	277	18	genetics	genetic	NOUN
easat-267	277	19	can	can	AUX
easat-267	277	20	teach	teach	VERB
easat-267	277	21	us	we	PRON
easat-267	277	22	about	about	ADP
easat-267	277	23	malaria	malaria	NOUN
easat-267	277	24	,	,	PUNCT
easat-267	277	25	"	"	PUNCT
easat-267	277	26	the	the	DET
easat-267	277	27	american	american	PROPN
easat-267	277	28	journal	journal	PROPN
easat-267	277	29	of	of	ADP
easat-267	277	30	human	human	ADJ
easat-267	277	31	genetics	genetic	NOUN
easat-267	277	32	,	,	PUNCT
easat-267	277	33	vol	vol	NOUN
easat-267	277	34	.	.	PROPN
easat-267	278	1	77	77	NUM
easat-267	278	2	,	,	PUNCT
easat-267	278	3	pp	pp	ADJ
easat-267	278	4	.	.	PUNCT
easat-267	279	1	171	171	NUM
easat-267	279	2	-	-	SYM
easat-267	279	3	192	192	NUM
easat-267	279	4	,	,	PUNCT
easat-267	279	5	2005	2005	NUM
easat-267	279	6	.	.	PUNCT
easat-267	280	1	https://doi.org/10.1086/432519	https://doi.org/10.1086/432519	VERB
easat-267	281	1	[	[	X
easat-267	281	2	16	16	NUM
easat-267	281	3	]	]	PUNCT
easat-267	281	4	c.	c.	PROPN
easat-267	281	5	lopez	lopez	PROPN
easat-267	281	6	,	,	PUNCT
easat-267	281	7	c.	c.	PROPN
easat-267	281	8	saravia	saravia	PROPN
easat-267	281	9	,	,	PUNCT
easat-267	281	10	a.	a.	PROPN
easat-267	281	11	gomez	gomez	PROPN
easat-267	281	12	,	,	PUNCT
easat-267	281	13	j.	j.	PROPN
easat-267	281	14	hoebeke	hoebeke	PROPN
easat-267	281	15	,	,	PUNCT
easat-267	281	16	and	and	CCONJ
easat-267	281	17	m.	m.	NOUN
easat-267	281	18	patarroyo	patarroyo	PROPN
easat-267	281	19	,	,	PUNCT
easat-267	281	20	"	"	PUNCT
easat-267	281	21	mechanisms	mechanism	NOUN
easat-267	281	22	of	of	ADP
easat-267	281	23	genetically	genetically	ADV
easat-267	281	24	-	-	PUNCT
easat-267	281	25	based	base	VERB
easat-267	281	26	resistance	resistance	NOUN
easat-267	281	27	to	to	ADP
easat-267	281	28	malaria	malaria	NOUN
easat-267	281	29	,	,	PUNCT
easat-267	281	30	"	"	PUNCT
easat-267	281	31	gene	gene	NOUN
easat-267	281	32	,	,	PUNCT
easat-267	281	33	vol	vol	NOUN
easat-267	281	34	.	.	PROPN
easat-267	281	35	467	467	NUM
easat-267	281	36	,	,	PUNCT
easat-267	281	37	pp	pp	ADJ
easat-267	281	38	.	.	PUNCT
easat-267	282	1	1	1	NUM
easat-267	282	2	-	-	SYM
easat-267	282	3	12	12	NUM
easat-267	282	4	,	,	PUNCT
easat-267	282	5	2010	2010	NUM
easat-267	282	6	.	.	PUNCT
easat-267	283	1	https://doi.org/10.1016/j.gene.2010.07.008	https://doi.org/10.1016/j.gene.2010.07.008	NOUN
easat-267	284	1	[	[	X
easat-267	284	2	17	17	NUM
easat-267	284	3	]	]	X
easat-267	284	4	s.	s.	PROPN
easat-267	284	5	taylor	taylor	PROPN
easat-267	284	6	,	,	PUNCT
easat-267	284	7	c.	c.	PROPN
easat-267	284	8	cerami	cerami	PROPN
easat-267	284	9	,	,	PUNCT
easat-267	284	10	and	and	CCONJ
easat-267	284	11	r.	r.	PROPN
easat-267	284	12	fairhurst	fairhurst	PROPN
easat-267	284	13	,	,	PUNCT
easat-267	284	14	"	"	PUNCT
easat-267	284	15	hemoglobinopathies	hemoglobinopathy	NOUN
easat-267	284	16	:	:	PUNCT
easat-267	284	17	slicing	slice	VERB
easat-267	284	18	the	the	DET
easat-267	284	19	gordian	gordian	ADJ
easat-267	284	20	knot	knot	NOUN
easat-267	284	21	of	of	ADP
easat-267	284	22	plasmodium	plasmodium	NOUN
easat-267	284	23	falciparum	falciparum	ADJ
easat-267	284	24	malaria	malaria	NOUN
easat-267	284	25	pathogenesis	pathogenesis	NOUN
easat-267	284	26	,	,	PUNCT
easat-267	284	27	"	"	PUNCT
easat-267	284	28	plos	plos	PROPN
easat-267	284	29	pathog	pathog	PROPN
easat-267	284	30	,	,	PUNCT
easat-267	284	31	vol	vol	NOUN
easat-267	284	32	.	.	NOUN
easat-267	284	33	9	9	NUM
easat-267	284	34	,	,	PUNCT
easat-267	284	35	p.	p.	NOUN
easat-267	284	36	e1003327	e1003327	PROPN
easat-267	284	37	,	,	PUNCT
easat-267	284	38	2013	2013	NUM
easat-267	284	39	.	.	PUNCT
easat-267	285	1	https://doi.org/10.1371/journal.ppat.1003327	https://doi.org/10.1371/journal.ppat.1003327	NOUN
easat-267	286	1	[	[	X
easat-267	286	2	18	18	NUM
easat-267	286	3	]	]	X
easat-267	286	4	p.	p.	NOUN
easat-267	286	5	hedrick	hedrick	PROPN
easat-267	286	6	,	,	PUNCT
easat-267	286	7	"	"	PUNCT
easat-267	286	8	resistance	resistance	NOUN
easat-267	286	9	to	to	ADP
easat-267	286	10	malaria	malaria	NOUN
easat-267	286	11	in	in	ADP
easat-267	286	12	humans	human	NOUN
easat-267	286	13	:	:	PUNCT
easat-267	286	14	the	the	DET
easat-267	286	15	impact	impact	NOUN
easat-267	286	16	of	of	ADP
easat-267	286	17	strong	strong	ADJ
easat-267	286	18	,	,	PUNCT
easat-267	286	19	recent	recent	ADJ
easat-267	286	20	selection	selection	NOUN
easat-267	286	21	,	,	PUNCT
easat-267	286	22	"	"	PUNCT
easat-267	286	23	malaria	malaria	NOUN
easat-267	286	24	journal	journal	NOUN
easat-267	286	25	,	,	PUNCT
easat-267	286	26	vol	vol	NOUN
easat-267	286	27	.	.	PROPN
easat-267	286	28	11	11	NUM
easat-267	286	29	,	,	PUNCT
easat-267	286	30	p.	p.	NOUN
easat-267	286	31	349	349	NUM
easat-267	286	32	,	,	PUNCT
easat-267	286	33	2012	2012	NUM
easat-267	286	34	.	.	PUNCT
easat-267	287	1	https://doi.org/10.1186/1475-2875-11-349	https://doi.org/10.1186/1475-2875-11-349	PROPN
easat-267	287	2	[	[	X
easat-267	287	3	19	19	NUM
easat-267	287	4	]	]	X
easat-267	287	5	v.	v.	PROPN
easat-267	287	6	pathak	pathak	PROPN
easat-267	287	7	,	,	PUNCT
easat-267	287	8	r.	r.	PROPN
easat-267	287	9	colah	colah	PROPN
easat-267	287	10	,	,	PUNCT
easat-267	287	11	and	and	CCONJ
easat-267	287	12	k.	k.	PROPN
easat-267	287	13	ghosh	ghosh	PROPN
easat-267	287	14	,	,	PUNCT
easat-267	287	15	"	"	PUNCT
easat-267	287	16	effect	effect	NOUN
easat-267	287	17	of	of	ADP
easat-267	287	18	inherited	inherit	VERB
easat-267	287	19	red	red	ADJ
easat-267	287	20	cell	cell	NOUN
easat-267	287	21	defects	defect	NOUN
easat-267	287	22	on	on	ADP
easat-267	287	23	growth	growth	NOUN
easat-267	287	24	of	of	ADP
easat-267	287	25	plasmodium	plasmodium	NOUN
easat-267	287	26	falciparum	falciparum	NOUN
easat-267	287	27	:	:	PUNCT
easat-267	287	28	an	an	DET
easat-267	287	29	in	in	ADP
easat-267	287	30	vitro	vitro	X
easat-267	287	31	study	study	NOUN
easat-267	287	32	,	,	PUNCT
easat-267	287	33	"	"	PUNCT
easat-267	287	34	indian	indian	ADJ
easat-267	287	35	journal	journal	NOUN
easat-267	287	36	of	of	ADP
easat-267	287	37	medical	medical	ADJ
easat-267	287	38	research	research	NOUN
easat-267	287	39	,	,	PUNCT
easat-267	287	40	vol	vol	NOUN
easat-267	287	41	.	.	PROPN
easat-267	287	42	147	147	NUM
easat-267	287	43	,	,	PUNCT
easat-267	287	44	pp	pp	ADJ
easat-267	287	45	.	.	PUNCT
easat-267	288	1	102	102	NUM
easat-267	288	2	-	-	SYM
easat-267	288	3	109	109	NUM
easat-267	288	4	,	,	PUNCT
easat-267	288	5	2018	2018	NUM
easat-267	288	6	.	.	PUNCT
easat-267	289	1	https://doi.org/10.1016/j.gene.2010.07.008	https://doi.org/10.1016/j.gene.2010.07.008	NOUN
easat-267	289	2	[	[	X
easat-267	289	3	20	20	NUM
easat-267	289	4	]	]	PUNCT
easat-267	289	5	j.	j.	PROPN
easat-267	289	6	goldsmith	goldsmith	PROPN
easat-267	289	7	,	,	PUNCT
easat-267	289	8	v.	v.	PROPN
easat-267	289	9	bonham	bonham	PROPN
easat-267	289	10	,	,	PUNCT
easat-267	289	11	c.	c.	PROPN
easat-267	289	12	joiner	joiner	PROPN
easat-267	289	13	,	,	PUNCT
easat-267	289	14	g.	g.	PROPN
easat-267	289	15	kato	kato	PROPN
easat-267	289	16	,	,	PUNCT
easat-267	289	17	and	and	CCONJ
easat-267	289	18	a.	a.	NOUN
easat-267	289	19	noonan	noonan	PROPN
easat-267	289	20	,	,	PUNCT
easat-267	289	21	"	"	PUNCT
easat-267	289	22	framing	frame	VERB
easat-267	289	23	the	the	DET
easat-267	289	24	research	research	NOUN
easat-267	289	25	agenda	agenda	NOUN
easat-267	289	26	for	for	ADP
easat-267	289	27	sickle	sickle	NOUN
easat-267	289	28	cell	cell	NOUN
easat-267	289	29	trait	trait	NOUN
easat-267	289	30	:	:	PUNCT
easat-267	289	31	building	build	VERB
easat-267	289	32	on	on	ADP
easat-267	289	33	the	the	DET
easat-267	289	34	current	current	ADJ
easat-267	289	35	understanding	understanding	NOUN
easat-267	289	36	of	of	ADP
easat-267	289	37	clinical	clinical	ADJ
easat-267	289	38	events	event	NOUN
easat-267	289	39	and	and	CCONJ
easat-267	289	40	their	their	PRON
easat-267	289	41	potential	potential	ADJ
easat-267	289	42	implications	implication	NOUN
easat-267	289	43	,	,	PUNCT
easat-267	289	44	"	"	PUNCT
easat-267	289	45	american	american	ADJ
easat-267	289	46	journal	journal	PROPN
easat-267	289	47	of	of	ADP
easat-267	289	48	hematology	hematology	NOUN
easat-267	289	49	,	,	PUNCT
easat-267	289	50	vol	vol	NOUN
easat-267	289	51	.	.	PROPN
easat-267	289	52	87	87	NUM
easat-267	289	53	,	,	PUNCT
easat-267	289	54	pp	pp	ADJ
easat-267	289	55	.	.	PUNCT
easat-267	290	1	340	340	NUM
easat-267	290	2	-	-	SYM
easat-267	290	3	346	346	NUM
easat-267	290	4	,	,	PUNCT
easat-267	290	5	2012	2012	NUM
easat-267	290	6	.	.	PUNCT
easat-267	291	1	https://doi.org/10.1002/ajh.22271	https://doi.org/10.1002/ajh.22271	VERB
easat-267	292	1	[	[	X
easat-267	292	2	21	21	NUM
easat-267	292	3	]	]	X
easat-267	292	4	r.	r.	PROPN
easat-267	292	5	balgir	balgir	PROPN
easat-267	292	6	,	,	PUNCT
easat-267	292	7	"	"	PUNCT
easat-267	292	8	public	public	ADJ
easat-267	292	9	health	health	NOUN
easat-267	292	10	challenges	challenge	NOUN
easat-267	292	11	of	of	ADP
easat-267	292	12	hemoglobinopathies	hemoglobinopathy	NOUN
easat-267	292	13	in	in	ADP
easat-267	292	14	tribal	tribal	ADJ
easat-267	292	15	land	land	NOUN
easat-267	292	16	of	of	ADP
easat-267	292	17	india	india	PROPN
easat-267	292	18	:	:	PUNCT
easat-267	292	19	a	a	DET
easat-267	292	20	necessity	necessity	NOUN
easat-267	292	21	of	of	ADP
easat-267	292	22	introducing	introduce	VERB
easat-267	292	23	genetic	genetic	ADJ
easat-267	292	24	services	service	NOUN
easat-267	292	25	in	in	ADP
easat-267	292	26	the	the	DET
easat-267	292	27	health	health	NOUN
easat-267	292	28	care	care	NOUN
easat-267	292	29	systems	system	NOUN
easat-267	292	30	approach	approach	NOUN
easat-267	292	31	,	,	PUNCT
easat-267	292	32	"	"	PUNCT
easat-267	292	33	br	br	PROPN
easat-267	292	34	biomed	biome	VERB
easat-267	292	35	bullet	bullet	NOUN
easat-267	292	36	,	,	PUNCT
easat-267	292	37	vol	vol	NOUN
easat-267	292	38	.	.	PROPN
easat-267	292	39	2	2	NUM
easat-267	292	40	,	,	PUNCT
easat-267	292	41	pp	pp	ADJ
easat-267	292	42	.	.	PUNCT
easat-267	293	1	489	489	NUM
easat-267	293	2	-	-	SYM
easat-267	293	3	503	503	NUM
easat-267	293	4	,	,	PUNCT
easat-267	293	5	2014	2014	NUM
easat-267	293	6	.	.	PUNCT
easat-267	294	1	[	[	X
easat-267	294	2	22	22	NUM
easat-267	294	3	]	]	X
easat-267	294	4	r.	r.	PROPN
easat-267	294	5	balgir	balgir	PROPN
easat-267	294	6	,	,	PUNCT
easat-267	294	7	"	"	PUNCT
easat-267	294	8	hematological	hematological	ADJ
easat-267	294	9	profile	profile	NOUN
easat-267	294	10	of	of	ADP
easat-267	294	11	hemoglobinopathies	hemoglobinopathy	NOUN
easat-267	294	12	in	in	ADP
easat-267	294	13	maternal	maternal	ADJ
easat-267	294	14	health	health	NOUN
easat-267	294	15	and	and	CCONJ
easat-267	294	16	reproductive	reproductive	ADJ
easat-267	294	17	outcome	outcome	NOUN
easat-267	294	18	in	in	ADP
easat-267	294	19	pregnant	pregnant	ADJ
easat-267	294	20	mothers	mother	NOUN
easat-267	294	21	at	at	ADP
easat-267	294	22	a	a	DET
easat-267	294	23	tertiary	tertiary	ADJ
easat-267	294	24	hospital	hospital	NOUN
easat-267	294	25	in	in	ADP
easat-267	294	26	central	central	ADJ
easat-267	294	27	india	india	PROPN
easat-267	294	28	,	,	PUNCT
easat-267	294	29	"	"	PUNCT
easat-267	294	30	journal	journal	NOUN
easat-267	294	31	of	of	ADP
easat-267	294	32	hematology	hematology	NOUN
easat-267	294	33	&	&	CCONJ
easat-267	294	34	multiple	multiple	ADJ
easat-267	294	35	myeloma	myeloma	PROPN
easat-267	294	36	vol	vol	NOUN
easat-267	294	37	.	.	PROPN
easat-267	295	1	3	3	NUM
easat-267	295	2	,	,	PUNCT
easat-267	295	3	p.	p.	NOUN
easat-267	295	4	1012	1012	NUM
easat-267	295	5	,	,	PUNCT
easat-267	295	6	2018	2018	NUM
easat-267	295	7	.	.	PUNCT
easat-267	296	1	[	[	X
easat-267	296	2	23	23	NUM
easat-267	296	3	]	]	PUNCT
easat-267	296	4	a.	a.	PROPN
easat-267	296	5	allison	allison	PROPN
easat-267	296	6	,	,	PUNCT
easat-267	296	7	"	"	PUNCT
easat-267	296	8	protection	protection	NOUN
easat-267	296	9	afforded	afford	VERB
easat-267	296	10	by	by	ADP
easat-267	296	11	the	the	DET
easat-267	296	12	sickle	sickle	NOUN
easat-267	296	13	cell	cell	NOUN
easat-267	296	14	trait	trait	NOUN
easat-267	296	15	against	against	ADP
easat-267	296	16	subtertian	subtertian	ADJ
easat-267	296	17	malarial	malarial	ADJ
easat-267	296	18	infection	infection	NOUN
easat-267	296	19	,	,	PUNCT
easat-267	296	20	"	"	PUNCT
easat-267	296	21	br	br	PROPN
easat-267	296	22	med	med	PROPN
easat-267	296	23	j	j	PROPN
easat-267	296	24	,	,	PUNCT
easat-267	296	25	vol	vol	NOUN
easat-267	296	26	.	.	PROPN
easat-267	296	27	1	1	NUM
easat-267	296	28	,	,	PUNCT
easat-267	296	29	pp	pp	ADJ
easat-267	296	30	.	.	PUNCT
easat-267	296	31	290294	290294	NUM
easat-267	296	32	,	,	PUNCT
easat-267	296	33	1954	1954	NUM
easat-267	296	34	.	.	PUNCT
easat-267	297	1	http://dx.doi.org/10.1136/bmj.1.4857.290	http://dx.doi.org/10.1136/bmj.1.4857.290	PROPN
easat-267	297	2	[	[	X
easat-267	297	3	24	24	NUM
easat-267	297	4	]	]	X
easat-267	297	5	r.	r.	PROPN
easat-267	297	6	balgir	balgir	PROPN
easat-267	297	7	,	,	PUNCT
easat-267	297	8	"	"	PUNCT
easat-267	297	9	prevalence	prevalence	NOUN
easat-267	297	10	of	of	ADP
easat-267	297	11	hemolytic	hemolytic	ADJ
easat-267	297	12	anemia	anemia	NOUN
easat-267	297	13	and	and	CCONJ
easat-267	297	14	hemoglobinopathies	hemoglobinopathy	NOUN
easat-267	297	15	among	among	ADP
easat-267	297	16	the	the	DET
easat-267	297	17	pregnant	pregnant	ADJ
easat-267	297	18	women	woman	NOUN
easat-267	297	19	attending	attend	VERB
easat-267	297	20	a	a	DET
easat-267	297	21	tertiary	tertiary	ADJ
easat-267	297	22	hospital	hospital	NOUN
easat-267	297	23	in	in	ADP
easat-267	297	24	central	central	ADJ
easat-267	297	25	india	india	PROPN
easat-267	297	26	,	,	PUNCT
easat-267	297	27	"	"	PUNCT
easat-267	297	28	thalassemia	thalassemia	NOUN
easat-267	297	29	reports	report	NOUN
easat-267	297	30	,	,	PUNCT
easat-267	297	31	vol	vol	NOUN
easat-267	297	32	.	.	PROPN
easat-267	297	33	5	5	NUM
easat-267	297	34	,	,	PUNCT
easat-267	297	35	pp	pp	ADJ
easat-267	297	36	.	.	PUNCT
easat-267	298	1	16	16	NUM
easat-267	298	2	-	-	SYM
easat-267	298	3	20	20	NUM
easat-267	298	4	,	,	PUNCT
easat-267	298	5	2015	2015	NUM
easat-267	298	6	.	.	PUNCT
easat-267	299	1	https://doi.org/10.4081/thal.2015.4644	https://doi.org/10.4081/thal.2015.4644	NOUN
easat-267	300	1	[	[	X
easat-267	300	2	25	25	NUM
easat-267	300	3	]	]	PUNCT
easat-267	300	4	p.	p.	NOUN
easat-267	300	5	olumese	olumese	PROPN
easat-267	300	6	,	,	PUNCT
easat-267	300	7	a.	a.	NOUN
easat-267	300	8	adeyemo	adeyemo	NOUN
easat-267	300	9	,	,	PUNCT
easat-267	300	10	o.	o.	PROPN
easat-267	300	11	ademowo	ademowo	PROPN
easat-267	300	12	,	,	PUNCT
easat-267	300	13	r.	r.	PROPN
easat-267	300	14	gbadegesin	gbadegesin	PROPN
easat-267	300	15	,	,	PUNCT
easat-267	300	16	and	and	CCONJ
easat-267	300	17	o.	o.	PROPN
easat-267	300	18	sodeinde	sodeinde	PROPN
easat-267	300	19	,	,	PUNCT
easat-267	300	20	"	"	PUNCT
easat-267	300	21	the	the	DET
easat-267	300	22	clinical	clinical	ADJ
easat-267	300	23	manifestations	manifestation	NOUN
easat-267	300	24	of	of	ADP
easat-267	300	25	cerebral	cerebral	ADJ
easat-267	300	26	malaria	malaria	NOUN
easat-267	300	27	among	among	ADP
easat-267	300	28	nigerian	nigerian	ADJ
easat-267	300	29	children	child	NOUN
easat-267	300	30	with	with	ADP
easat-267	300	31	the	the	DET
easat-267	300	32	sickle	sickle	NOUN
easat-267	300	33	cell	cell	NOUN
easat-267	300	34	trait	trait	NOUN
easat-267	300	35	,	,	PUNCT
easat-267	300	36	"	"	PUNCT
easat-267	300	37	ann	ann	PROPN
easat-267	300	38	trop	trop	X
easat-267	300	39	paediat	paediat	PROPN
easat-267	300	40	,	,	PUNCT
easat-267	300	41	vol	vol	NOUN
easat-267	300	42	.	.	PROPN
easat-267	300	43	17	17	NUM
easat-267	300	44	,	,	PUNCT
easat-267	300	45	pp	pp	ADJ
easat-267	300	46	.	.	PUNCT
easat-267	301	1	141	141	NUM
easat-267	301	2	-	-	SYM
easat-267	301	3	145	145	NUM
easat-267	301	4	,	,	PUNCT
easat-267	301	5	1997	1997	NUM
easat-267	301	6	.	.	PUNCT
easat-267	302	1	https://doi.org/10.1080/02724936.1997.11747877	https://doi.org/10.1080/02724936.1997.11747877	PROPN
easat-267	303	1	[	[	X
easat-267	303	2	26	26	NUM
easat-267	303	3	]	]	X
easat-267	303	4	l.	l.	PROPN
easat-267	303	5	luzzatto	luzzatto	PROPN
easat-267	303	6	and	and	CCONJ
easat-267	303	7	a.	a.	NOUN
easat-267	303	8	pinching	pinching	NOUN
easat-267	303	9	,	,	PUNCT
easat-267	303	10	"	"	PUNCT
easat-267	303	11	commentary	commentary	NOUN
easat-267	303	12	to	to	ADP
easat-267	303	13	r	r	PROPN
easat-267	303	14	nagel	nagel	PROPN
easat-267	303	15	-innate	-innate	PROPN
easat-267	303	16	resistance	resistance	NOUN
easat-267	303	17	to	to	ADP
easat-267	303	18	malaria	malaria	NOUN
easat-267	303	19	:	:	PUNCT
easat-267	303	20	the	the	DET
easat-267	303	21	intra	intra	ADJ
easat-267	303	22	-	-	ADJ
easat-267	303	23	erythrocytic	erythrocytic	ADJ
easat-267	303	24	cycle	cycle	NOUN
easat-267	303	25	,	,	PUNCT
easat-267	303	26	"	"	PUNCT
easat-267	303	27	blood	blood	NOUN
easat-267	303	28	cells	cell	NOUN
easat-267	303	29	,	,	PUNCT
easat-267	303	30	vol	vol	NOUN
easat-267	303	31	.	.	PROPN
easat-267	303	32	16	16	NUM
easat-267	303	33	,	,	PUNCT
easat-267	303	34	pp	pp	ADJ
easat-267	303	35	.	.	PUNCT
easat-267	304	1	340	340	NUM
easat-267	304	2	-	-	SYM
easat-267	304	3	347	347	NUM
easat-267	304	4	,	,	PUNCT
easat-267	304	5	1990	1990	NUM
easat-267	304	6	.	.	PUNCT
easat-267	305	1	[	[	X
easat-267	305	2	27	27	NUM
easat-267	305	3	]	]	X
easat-267	305	4	k.	k.	PROPN
easat-267	305	5	ayi	ayi	PROPN
easat-267	305	6	,	,	PUNCT
easat-267	305	7	f.	f.	PROPN
easat-267	305	8	turrini	turrini	PROPN
easat-267	305	9	,	,	PUNCT
easat-267	305	10	a.	a.	NOUN
easat-267	305	11	piga	piga	PROPN
easat-267	305	12	,	,	PUNCT
easat-267	305	13	and	and	CCONJ
easat-267	305	14	p.	p.	NOUN
easat-267	305	15	arese	arese	NOUN
easat-267	305	16	,	,	PUNCT
easat-267	305	17	"	"	PUNCT
easat-267	305	18	enhanced	enhance	VERB
easat-267	305	19	phagocytosis	phagocytosis	NOUN
easat-267	305	20	of	of	ADP
easat-267	305	21	ring	ring	NOUN
easat-267	305	22	-	-	PUNCT
easat-267	305	23	parasitized	parasitize	VERB
easat-267	305	24	mutant	mutant	ADJ
easat-267	305	25	erythrocytes	erythrocyte	NOUN
easat-267	305	26	:	:	PUNCT
easat-267	305	27	a	a	DET
easat-267	305	28	common	common	ADJ
easat-267	305	29	mechanism	mechanism	NOUN
easat-267	305	30	that	that	PRON
easat-267	305	31	may	may	AUX
easat-267	305	32	explain	explain	VERB
easat-267	305	33	protection	protection	NOUN
easat-267	305	34	against	against	ADP
easat-267	305	35	falciparum	falciparum	ADJ
easat-267	305	36	malaria	malaria	NOUN
easat-267	305	37	in	in	ADP
easat-267	305	38	sickle	sickle	NOUN
easat-267	305	39	trait	trait	NOUN
easat-267	305	40	and	and	CCONJ
easat-267	305	41	beta	beta	NOUN
easat-267	305	42	-	-	PUNCT
easat-267	305	43	thalassemia	thalassemia	NOUN
easat-267	305	44	trait	trait	NOUN
easat-267	305	45	,	,	PUNCT
easat-267	305	46	"	"	PUNCT
easat-267	305	47	blood	blood	NOUN
easat-267	305	48	,	,	PUNCT
easat-267	305	49	vol	vol	NOUN
easat-267	305	50	.	.	PROPN
easat-267	306	1	104	104	NUM
easat-267	306	2	,	,	PUNCT
easat-267	306	3	pp	pp	ADJ
easat-267	306	4	.	.	PUNCT
easat-267	307	1	3364	3364	NUM
easat-267	307	2	-	-	SYM
easat-267	307	3	3371	3371	NUM
easat-267	307	4	,	,	PUNCT
easat-267	307	5	2004	2004	NUM
easat-267	307	6	.	.	PUNCT
easat-267	308	1	http://dx.doi.org/10.1182/blood-2003-11-3820	http://dx.doi.org/10.1182/blood-2003-11-3820	NOUN
easat-267	309	1	[	[	X
easat-267	309	2	28	28	NUM
easat-267	309	3	]	]	X
easat-267	309	4	l.	l.	PROPN
easat-267	309	5	luzzatto	luzzatto	PROPN
easat-267	309	6	,	,	PUNCT
easat-267	309	7	e.	e.	PROPN
easat-267	309	8	nwachuku	nwachuku	PROPN
easat-267	309	9	-	-	PUNCT
easat-267	309	10	jarrett	jarrett	PROPN
easat-267	309	11	,	,	PUNCT
easat-267	309	12	and	and	CCONJ
easat-267	309	13	s.	s.	PROPN
easat-267	309	14	reddy	reddy	PROPN
easat-267	309	15	,	,	PUNCT
easat-267	309	16	"	"	PUNCT
easat-267	309	17	increased	increase	VERB
easat-267	309	18	sickling	sickling	NOUN
easat-267	309	19	of	of	ADP
easat-267	309	20	parasitised	parasitise	VERB
easat-267	309	21	erythrocytes	erythrocyte	NOUN
easat-267	309	22	as	as	ADP
easat-267	309	23	mechanism	mechanism	NOUN
easat-267	309	24	of	of	ADP
easat-267	309	25	resistance	resistance	NOUN
easat-267	309	26	against	against	ADP
easat-267	309	27	malaria	malaria	NOUN
easat-267	309	28	in	in	ADP
easat-267	309	29	the	the	DET
easat-267	309	30	sickle	sickle	NOUN
easat-267	309	31	-	-	PUNCT
easat-267	309	32	cell	cell	NOUN
easat-267	309	33	trait	trait	NOUN
easat-267	309	34	,	,	PUNCT
easat-267	309	35	"	"	PUNCT
easat-267	309	36	lancet	lancet	NOUN
easat-267	309	37	,	,	PUNCT
easat-267	309	38	vol	vol	NOUN
easat-267	309	39	.	.	PROPN
easat-267	309	40	1	1	NUM
easat-267	309	41	,	,	PUNCT
easat-267	309	42	pp	pp	ADJ
easat-267	309	43	.	.	PUNCT
easat-267	310	1	319	319	NUM
easat-267	310	2	-	-	SYM
easat-267	310	3	321	321	NUM
easat-267	310	4	,	,	PUNCT
easat-267	310	5	1970	1970	NUM
easat-267	310	6	.	.	PUNCT
easat-267	311	1	http://dx.doi.org/10.1016/s0140-6736(70)90700-2	http://dx.doi.org/10.1016/s0140-6736(70)90700-2	PRON
easat-267	311	2	[	[	X
easat-267	311	3	29	29	NUM
easat-267	311	4	]	]	PUNCT
easat-267	311	5	l.	l.	PROPN
easat-267	311	6	g.	g.	PROPN
easat-267	311	7	luzzatto	luzzatto	PROPN
easat-267	311	8	,	,	PUNCT
easat-267	311	9	"	"	PUNCT
easat-267	311	10	enetics	enetic	NOUN
easat-267	311	11	of	of	ADP
easat-267	311	12	red	red	ADJ
easat-267	311	13	cells	cell	NOUN
easat-267	311	14	and	and	CCONJ
easat-267	311	15	susceptibility	susceptibility	NOUN
easat-267	311	16	to	to	ADP
easat-267	311	17	malaria	malaria	NOUN
easat-267	311	18	,	,	PUNCT
easat-267	311	19	"	"	PUNCT
easat-267	311	20	blood	blood	NOUN
easat-267	311	21	,	,	PUNCT
easat-267	311	22	vol	vol	NOUN
easat-267	311	23	.	.	PROPN
easat-267	311	24	54	54	NUM
easat-267	311	25	,	,	PUNCT
easat-267	311	26	pp	pp	ADJ
easat-267	311	27	.	.	PUNCT
easat-267	312	1	961	961	NUM
easat-267	312	2	-	-	SYM
easat-267	312	3	976	976	NUM
easat-267	312	4	,	,	PUNCT
easat-267	312	5	1979	1979	NUM
easat-267	312	6	.	.	PUNCT
easat-267	313	1	[	[	X
easat-267	313	2	30	30	NUM
easat-267	313	3	]	]	X
easat-267	313	4	r.	r.	PROPN
easat-267	313	5	balgir	balgir	PROPN
easat-267	313	6	,	,	PUNCT
easat-267	313	7	"	"	PUNCT
easat-267	313	8	ethnic	ethnic	ADJ
easat-267	313	9	and	and	CCONJ
easat-267	313	10	regional	regional	ADJ
easat-267	313	11	variations	variation	NOUN
easat-267	313	12	in	in	ADP
easat-267	313	13	the	the	DET
easat-267	313	14	red	red	ADJ
easat-267	313	15	cell	cell	NOUN
easat-267	313	16	glucose-6	glucose-6	NOUN
easat-267	313	17	-	-	PUNCT
easat-267	313	18	phosphate	phosphate	NOUN
easat-267	313	19	dehydrogenase	dehydrogenase	NOUN
easat-267	313	20	deficiency	deficiency	NOUN
easat-267	313	21	in	in	ADP
easat-267	313	22	india	india	PROPN
easat-267	313	23	,	,	PUNCT
easat-267	313	24	"	"	PUNCT
easat-267	313	25	indian	indian	ADJ
easat-267	313	26	journal	journal	NOUN
easat-267	313	27	of	of	ADP
easat-267	313	28	hematology	hematology	NOUN
easat-267	313	29	,	,	PUNCT
easat-267	313	30	vol	vol	NOUN
easat-267	313	31	.	.	PROPN
easat-267	313	32	7	7	NUM
easat-267	313	33	,	,	PUNCT
easat-267	313	34	pp	pp	ADJ
easat-267	313	35	.	.	PUNCT
easat-267	314	1	101	101	NUM
easat-267	314	2	-	-	SYM
easat-267	314	3	9	9	NUM
easat-267	314	4	,	,	PUNCT
easat-267	314	5	1989	1989	NUM
easat-267	314	6	.	.	PUNCT
easat-267	315	1	[	[	X
easat-267	315	2	31	31	NUM
easat-267	315	3	]	]	PUNCT
easat-267	315	4	m.	m.	NOUN
easat-267	315	5	cappadoro	cappadoro	NOUN
easat-267	315	6	,	,	PUNCT
easat-267	315	7	g.	g.	PROPN
easat-267	315	8	giribaldi	giribaldi	PROPN
easat-267	315	9	,	,	PUNCT
easat-267	315	10	e.	e.	PROPN
easat-267	315	11	o'brien	o'brien	PROPN
easat-267	315	12	,	,	PUNCT
easat-267	315	13	f.	f.	PROPN
easat-267	315	14	turrini	turrini	PROPN
easat-267	315	15	,	,	PUNCT
easat-267	315	16	and	and	CCONJ
easat-267	315	17	f.	f.	PROPN
easat-267	315	18	mannu	mannu	PROPN
easat-267	315	19	,	,	PUNCT
easat-267	315	20	"	"	PUNCT
easat-267	315	21	early	early	ADJ
easat-267	315	22	phagocytosis	phagocytosis	NOUN
easat-267	315	23	of	of	ADP
easat-267	315	24	glucose-6	glucose-6	NOUN
easat-267	315	25	-	-	PUNCT
easat-267	315	26	phosphate	phosphate	NOUN
easat-267	315	27	dehydrogenase	dehydrogenase	NOUN
easat-267	315	28	(	(	PUNCT
easat-267	315	29	g6pd)-deficient	g6pd)-deficient	PROPN
easat-267	315	30	erythrocytes	erythrocyte	NOUN
easat-267	315	31	parasitized	parasitize	VERB
easat-267	315	32	by	by	ADP
easat-267	315	33	plasmodium	plasmodium	NOUN
easat-267	315	34	falciparum	falciparum	NOUN
easat-267	315	35	may	may	AUX
easat-267	315	36	explain	explain	VERB
easat-267	315	37	malaria	malaria	NOUN
easat-267	315	38	protection	protection	NOUN
easat-267	315	39	in	in	ADP
easat-267	315	40	g6pd	g6pd	NOUN
easat-267	315	41	deficiency	deficiency	NOUN
easat-267	315	42	,	,	PUNCT
easat-267	315	43	"	"	PUNCT
easat-267	315	44	blood	blood	NOUN
easat-267	315	45	,	,	PUNCT
easat-267	315	46	vol	vol	NOUN
easat-267	315	47	.	.	PROPN
easat-267	315	48	92	92	NUM
easat-267	315	49	,	,	PUNCT
easat-267	315	50	pp	pp	ADJ
easat-267	315	51	.	.	PUNCT
easat-267	315	52	2527	2527	NUM
easat-267	315	53	-	-	SYM
easat-267	315	54	2534	2534	NUM
easat-267	315	55	,	,	PUNCT
easat-267	315	56	1998	1998	NUM
easat-267	315	57	.	.	PUNCT
easat-267	316	1	https://doi.org/10.1182/blood.v92.7.2527.2527_2527_2534	https://doi.org/10.1182/blood.v92.7.2527.2527_2527_2534	PROPN
easat-267	316	2	https://doi.org/10.1016/j.jchb.2006.01.003	https://doi.org/10.1016/j.jchb.2006.01.003	PROPN
easat-267	316	3	https://doi.org/10.2174/187152512799201190	https://doi.org/10.2174/187152512799201190	PROPN
easat-267	316	4	https://doi.org/10.1002/ajpa.1330750310	https://doi.org/10.1002/ajpa.1330750310	NOUN
easat-267	316	5	https://doi.org/10.1080/09720073.2004.11890830	https://doi.org/10.1080/09720073.2004.11890830	PROPN
easat-267	316	6	https://doi.org/10.1080/03014460500228741	https://doi.org/10.1080/03014460500228741	NOUN
easat-267	316	7	https://doi.org/10.1080/03014460500228741	https://doi.org/10.1080/03014460500228741	ADV
easat-267	316	8	https://doi.org/10.1007/s12687-010-0016-y	https://doi.org/10.1007/s12687-010-0016-y	PROPN
easat-267	316	9	https://doi.org/10.3109/03630269.2011.600491	https://doi.org/10.3109/03630269.2011.600491	PROPN
easat-267	316	10	https://doi.org/10.4084/mjhid.2012.065	https://doi.org/10.4084/mjhid.2012.065	PROPN
easat-267	316	11	https://doi.org/10.1086/432519	https://doi.org/10.1086/432519	VERB
easat-267	316	12	https://doi.org/10.1016/j.gene.2010.07.008	https://doi.org/10.1016/j.gene.2010.07.008	PRON
easat-267	316	13	https://doi.org/10.1371/journal.ppat.1003327	https://doi.org/10.1371/journal.ppat.1003327	NOUN
easat-267	316	14	https://doi.org/10.1186/1475-2875-11-349	https://doi.org/10.1186/1475-2875-11-349	PROPN
easat-267	316	15	https://doi.org/10.1016/j.gene.2010.07.008	https://doi.org/10.1016/j.gene.2010.07.008	NOUN
easat-267	316	16	https://doi.org/10.1002/ajh.22271	https://doi.org/10.1002/ajh.22271	NOUN
easat-267	316	17	http://dx.doi.org/10.1136/bmj.1.4857.290	http://dx.doi.org/10.1136/bmj.1.4857.290	ADJ
easat-267	316	18	https://doi.org/10.4081/thal.2015.4644	https://doi.org/10.4081/thal.2015.4644	PROPN
easat-267	316	19	https://doi.org/10.1080/02724936.1997.11747877	https://doi.org/10.1080/02724936.1997.11747877	PROPN
easat-267	316	20	http://dx.doi.org/10.1182/blood-2003-11-3820	http://dx.doi.org/10.1182/blood-2003-11-3820	NOUN
easat-267	316	21	http://dx.doi.org/10.1016/s0140-6736(70)90700-2	http://dx.doi.org/10.1016/s0140-6736(70)90700-2	PROPN
easat-267	316	22	https://doi.org/10.1182/blood.v92.7.2527.2527_2527_2534	https://doi.org/10.1182/blood.v92.7.2527.2527_2527_2534	PROPN
easat-267	316	23	52	52	NUM
easat-267	316	24	edelweiss	edelweiss	PROPN
easat-267	316	25	applied	apply	VERB
easat-267	316	26	science	science	NOUN
easat-267	316	27	and	and	CCONJ
easat-267	316	28	technology	technology	NOUN
easat-267	316	29	issn	issn	PROPN
easat-267	316	30	:	:	PUNCT
easat-267	316	31	2576	2576	NUM
easat-267	316	32	-	-	SYM
easat-267	316	33	8484	8484	NUM
easat-267	316	34	vol	vol	NOUN
easat-267	316	35	.	.	PROPN
easat-267	317	1	3	3	NUM
easat-267	317	2	,	,	PUNCT
easat-267	317	3	no	no	INTJ
easat-267	317	4	.	.	NOUN
easat-267	317	5	1	1	NUM
easat-267	317	6	:	:	SYM
easat-267	317	7	44	44	NUM
easat-267	317	8	-	-	SYM
easat-267	317	9	52	52	NUM
easat-267	317	10	,	,	PUNCT
easat-267	317	11	2019	2019	NUM
easat-267	317	12	doi	doi	NOUN
easat-267	317	13	:	:	PUNCT
easat-267	317	14	10.33805/2576	10.33805/2576	NUM
easat-267	317	15	-	-	SYM
easat-267	317	16	8484.167	8484.167	NUM
easat-267	317	17	©	©	PROPN
easat-267	317	18	2019	2019	NUM
easat-267	317	19	by	by	ADP
easat-267	317	20	the	the	DET
easat-267	317	21	author	author	NOUN
easat-267	317	22	[	[	X
easat-267	317	23	32	32	NUM
easat-267	317	24	]	]	PUNCT
easat-267	317	25	r.	r.	PROPN
easat-267	317	26	balgir	balgir	PROPN
easat-267	317	27	,	,	PUNCT
easat-267	317	28	r.	r.	PROPN
easat-267	317	29	mishra	mishra	PROPN
easat-267	317	30	,	,	PUNCT
easat-267	317	31	and	and	CCONJ
easat-267	317	32	b.	b.	PROPN
easat-267	317	33	murmu	murmu	PROPN
easat-267	317	34	,	,	PUNCT
easat-267	317	35	"	"	PUNCT
easat-267	317	36	clinical	clinical	ADJ
easat-267	317	37	and	and	CCONJ
easat-267	317	38	hematological	hematological	ADJ
easat-267	317	39	profile	profile	NOUN
easat-267	317	40	of	of	ADP
easat-267	317	41	hemoglobinopathies	hemoglobinopathy	NOUN
easat-267	317	42	in	in	ADP
easat-267	317	43	two	two	NUM
easat-267	317	44	tribal	tribal	ADJ
easat-267	317	45	communities	community	NOUN
easat-267	317	46	of	of	ADP
easat-267	317	47	sundargarh	sundargarh	NOUN
easat-267	317	48	district	district	NOUN
easat-267	317	49	in	in	ADP
easat-267	317	50	orissa	orissa	PROPN
easat-267	317	51	,	,	PUNCT
easat-267	317	52	india	india	PROPN
easat-267	317	53	,	,	PUNCT
easat-267	317	54	"	"	PUNCT
easat-267	317	55	international	international	ADJ
easat-267	317	56	journal	journal	NOUN
easat-267	317	57	of	of	ADP
easat-267	317	58	human	human	ADJ
easat-267	317	59	genetics	genetic	NOUN
easat-267	317	60	,	,	PUNCT
easat-267	317	61	vol	vol	NOUN
easat-267	317	62	.	.	PROPN
easat-267	318	1	3	3	NUM
easat-267	318	2	,	,	PUNCT
easat-267	318	3	pp	pp	ADJ
easat-267	318	4	.	.	PUNCT
easat-267	319	1	209	209	NUM
easat-267	319	2	-	-	SYM
easat-267	319	3	216	216	NUM
easat-267	319	4	,	,	PUNCT
easat-267	319	5	2003	2003	NUM
easat-267	319	6	.	.	PUNCT
easat-267	320	1	https://doi.org/10.1080/09723757.2003.11885854	https://doi.org/10.1080/09723757.2003.11885854	X
easat-267	321	1	[	[	X
easat-267	321	2	33	33	NUM
easat-267	321	3	]	]	PUNCT
easat-267	321	4	g.	g.	PROPN
easat-267	321	5	cabrera	cabrera	PROPN
easat-267	321	6	,	,	PUNCT
easat-267	321	7	m.	m.	NOUN
easat-267	321	8	cot	cot	PROPN
easat-267	321	9	,	,	PUNCT
easat-267	321	10	f.	f.	PROPN
easat-267	321	11	migotnabias	migotnabias	PROPN
easat-267	321	12	,	,	PUNCT
easat-267	321	13	p.	p.	NOUN
easat-267	321	14	kremsner	kremsner	NOUN
easat-267	321	15	,	,	PUNCT
easat-267	321	16	and	and	CCONJ
easat-267	321	17	p.	p.	NOUN
easat-267	321	18	deloron	deloron	NOUN
easat-267	321	19	,	,	PUNCT
easat-267	321	20	"	"	PUNCT
easat-267	321	21	the	the	DET
easat-267	321	22	sickle	sickle	NOUN
easat-267	321	23	cell	cell	NOUN
easat-267	321	24	trait	trait	NOUN
easat-267	321	25	is	be	AUX
easat-267	321	26	associated	associate	VERB
easat-267	321	27	with	with	ADP
easat-267	321	28	enhanced	enhanced	ADJ
easat-267	321	29	immunoglobulin	immunoglobulin	NOUN
easat-267	321	30	g	g	PROPN
easat-267	321	31	antibody	antibody	NOUN
easat-267	321	32	responses	response	NOUN
easat-267	321	33	to	to	ADP
easat-267	321	34	plasmodium	plasmodium	NOUN
easat-267	321	35	falciparum	falciparum	ADJ
easat-267	321	36	variant	variant	ADJ
easat-267	321	37	surface	surface	NOUN
easat-267	321	38	antigens	antigen	NOUN
easat-267	321	39	,	,	PUNCT
easat-267	321	40	"	"	PUNCT
easat-267	321	41	the	the	DET
easat-267	321	42	journal	journal	NOUN
easat-267	321	43	of	of	ADP
easat-267	321	44	infectious	infectious	ADJ
easat-267	321	45	diseases	disease	NOUN
easat-267	321	46	,	,	PUNCT
easat-267	321	47	vol	vol	NOUN
easat-267	321	48	.	.	PROPN
easat-267	321	49	191	191	NUM
easat-267	321	50	,	,	PUNCT
easat-267	321	51	pp	pp	ADJ
easat-267	321	52	.	.	PUNCT
easat-267	322	1	1631	1631	NUM
easat-267	322	2	-	-	SYM
easat-267	322	3	1638	1638	NUM
easat-267	322	4	,	,	PUNCT
easat-267	322	5	2005	2005	NUM
easat-267	322	6	.	.	PUNCT
easat-267	323	1	https://doi.org/10.1086/429832	https://doi.org/10.1086/429832	X
easat-267	323	2	[	[	X
easat-267	323	3	34	34	NUM
easat-267	323	4	]	]	X
easat-267	323	5	r.	r.	PROPN
easat-267	323	6	cholera	cholera	PROPN
easat-267	323	7	,	,	PUNCT
easat-267	323	8	n.	n.	PROPN
easat-267	323	9	brittain	brittain	PROPN
easat-267	323	10	,	,	PUNCT
easat-267	323	11	m.	m.	NOUN
easat-267	323	12	gillrie	gillrie	PROPN
easat-267	323	13	,	,	PUNCT
easat-267	323	14	t.	t.	PROPN
easat-267	323	15	lopera	lopera	PROPN
easat-267	323	16	-	-	PUNCT
easat-267	323	17	mesa	mesa	PROPN
easat-267	323	18	,	,	PUNCT
easat-267	323	19	and	and	CCONJ
easat-267	323	20	s.	s.	PROPN
easat-267	323	21	diakite	diakite	PROPN
easat-267	323	22	,	,	PUNCT
easat-267	323	23	"	"	PUNCT
easat-267	323	24	impaired	impaired	ADJ
easat-267	323	25	cytoadherence	cytoadherence	NOUN
easat-267	323	26	of	of	ADP
easat-267	323	27	plasmodium	plasmodium	NOUN
easat-267	323	28	falciparum	falciparum	NOUN
easat-267	323	29	-	-	PUNCT
easat-267	323	30	infected	infect	VERB
easat-267	323	31	erythrocytes	erythrocyte	NOUN
easat-267	323	32	containing	contain	VERB
easat-267	323	33	sickle	sickle	NOUN
easat-267	323	34	hemoglobin	hemoglobin	NOUN
easat-267	323	35	,	,	PUNCT
easat-267	323	36	"	"	PUNCT
easat-267	323	37	proceedings	proceeding	NOUN
easat-267	323	38	of	of	ADP
easat-267	323	39	the	the	DET
easat-267	323	40	national	national	PROPN
easat-267	323	41	academy	academy	PROPN
easat-267	323	42	of	of	ADP
easat-267	323	43	sciences	sciences	PROPN
easat-267	323	44	of	of	ADP
easat-267	323	45	the	the	DET
easat-267	323	46	united	united	PROPN
easat-267	323	47	states	states	PROPN
easat-267	323	48	of	of	ADP
easat-267	323	49	america	america	PROPN
easat-267	323	50	,	,	PUNCT
easat-267	323	51	vol	vol	NOUN
easat-267	323	52	.	.	PROPN
easat-267	323	53	105	105	NUM
easat-267	323	54	,	,	PUNCT
easat-267	323	55	pp	pp	ADJ
easat-267	323	56	.	.	PUNCT
easat-267	324	1	991	991	NUM
easat-267	324	2	-	-	SYM
easat-267	324	3	996	996	NUM
easat-267	324	4	,	,	PUNCT
easat-267	324	5	2008	2008	NUM
easat-267	324	6	.	.	PUNCT
easat-267	325	1	http://dx.doi.org/10.1073/pnas.0711401105	http://dx.doi.org/10.1073/pnas.0711401105	X
easat-267	326	1	[	[	X
easat-267	326	2	35	35	NUM
easat-267	326	3	]	]	PUNCT
easat-267	326	4	a.	a.	NOUN
easat-267	326	5	adeloye	adeloye	PROPN
easat-267	326	6	,	,	PUNCT
easat-267	326	7	l.	l.	PROPN
easat-267	326	8	luzzatto	luzzatto	PROPN
easat-267	326	9	,	,	PUNCT
easat-267	326	10	and	and	CCONJ
easat-267	326	11	g.	g.	PROPN
easat-267	326	12	edington	edington	PROPN
easat-267	326	13	,	,	PUNCT
easat-267	326	14	"	"	PUNCT
easat-267	326	15	severe	severe	ADJ
easat-267	326	16	malarial	malarial	ADJ
easat-267	326	17	infection	infection	NOUN
easat-267	326	18	in	in	ADP
easat-267	326	19	a	a	DET
easat-267	326	20	patient	patient	NOUN
easat-267	326	21	with	with	ADP
easat-267	326	22	sickle	sickle	NOUN
easat-267	326	23	-	-	PUNCT
easat-267	326	24	cell	cell	NOUN
easat-267	326	25	anaemia	anaemia	NOUN
easat-267	326	26	,	,	PUNCT
easat-267	326	27	"	"	PUNCT
easat-267	326	28	br	br	PROPN
easat-267	326	29	med	med	PROPN
easat-267	326	30	j	j	PROPN
easat-267	326	31	,	,	PUNCT
easat-267	326	32	vol	vol	NOUN
easat-267	326	33	.	.	PROPN
easat-267	326	34	2	2	NUM
easat-267	326	35	,	,	PUNCT
easat-267	326	36	pp	pp	ADJ
easat-267	326	37	.	.	PUNCT
easat-267	327	1	445	445	NUM
easat-267	327	2	-	-	SYM
easat-267	327	3	446	446	NUM
easat-267	327	4	,	,	PUNCT
easat-267	327	5	1971	1971	NUM
easat-267	327	6	.	.	PUNCT
easat-267	328	1	http://dx.doi.org/10.1136/bmj.2.5759.445	http://dx.doi.org/10.1136/bmj.2.5759.445	PROPN
easat-267	329	1	[	[	X
easat-267	329	2	36	36	NUM
easat-267	329	3	]	]	X
easat-267	329	4	d.	d.	PROPN
easat-267	329	5	weatherall	weatherall	PROPN
easat-267	329	6	,	,	PUNCT
easat-267	329	7	"	"	PUNCT
easat-267	329	8	genetic	genetic	ADJ
easat-267	329	9	variation	variation	NOUN
easat-267	329	10	and	and	CCONJ
easat-267	329	11	susceptibility	susceptibility	NOUN
easat-267	329	12	to	to	ADP
easat-267	329	13	infection	infection	NOUN
easat-267	329	14	:	:	PUNCT
easat-267	329	15	the	the	DET
easat-267	329	16	red	red	ADJ
easat-267	329	17	cell	cell	NOUN
easat-267	329	18	and	and	CCONJ
easat-267	329	19	malaria	malaria	NOUN
easat-267	329	20	,	,	PUNCT
easat-267	329	21	"	"	PUNCT
easat-267	329	22	british	british	ADJ
easat-267	329	23	journal	journal	PROPN
easat-267	329	24	of	of	ADP
easat-267	329	25	haematology	haematology	NOUN
easat-267	329	26	,	,	PUNCT
easat-267	329	27	vol	vol	NOUN
easat-267	329	28	.	.	PROPN
easat-267	329	29	141	141	NUM
easat-267	329	30	,	,	PUNCT
easat-267	329	31	pp	pp	ADJ
easat-267	329	32	.	.	PUNCT
easat-267	330	1	276	276	NUM
easat-267	330	2	-	-	SYM
easat-267	330	3	286	286	NUM
easat-267	330	4	,	,	PUNCT
easat-267	330	5	2008	2008	NUM
easat-267	330	6	.	.	PUNCT
easat-267	331	1	https://doi.org/10.1111/j.1365-2141.2008.07085.x	https://doi.org/10.1111/j.1365-2141.2008.07085.x	ADJ
easat-267	331	2	[	[	X
easat-267	331	3	37	37	NUM
easat-267	331	4	]	]	PUNCT
easat-267	331	5	r.	r.	PROPN
easat-267	331	6	balgir	balgir	PROPN
easat-267	331	7	,	,	PUNCT
easat-267	331	8	"	"	PUNCT
easat-267	331	9	population	population	NOUN
easat-267	331	10	and	and	CCONJ
easat-267	331	11	public	public	ADJ
easat-267	331	12	health	health	NOUN
easat-267	331	13	implications	implication	NOUN
easat-267	331	14	of	of	ADP
easat-267	331	15	child	child	NOUN
easat-267	331	16	health	health	NOUN
easat-267	331	17	and	and	CCONJ
easat-267	331	18	reproductive	reproductive	ADJ
easat-267	331	19	outcomes	outcome	NOUN
easat-267	331	20	among	among	ADP
easat-267	331	21	carrier	carrier	NOUN
easat-267	331	22	couples	couple	NOUN
easat-267	331	23	of	of	ADP
easat-267	331	24	sickle	sickle	NOUN
easat-267	331	25	cell	cell	NOUN
easat-267	331	26	disorders	disorder	NOUN
easat-267	331	27	in	in	ADP
easat-267	331	28	madhya	madhya	PROPN
easat-267	331	29	pradesh	pradesh	PROPN
easat-267	331	30	,	,	PUNCT
easat-267	331	31	india	india	PROPN
easat-267	331	32	,	,	PUNCT
easat-267	331	33	"	"	PUNCT
easat-267	331	34	international	international	ADJ
easat-267	331	35	journal	journal	NOUN
easat-267	331	36	of	of	ADP
easat-267	331	37	maternal	maternal	ADJ
easat-267	331	38	and	and	CCONJ
easat-267	331	39	child	child	NOUN
easat-267	331	40	health	health	NOUN
easat-267	331	41	and	and	CCONJ
easat-267	331	42	aids	aids	PROPN
easat-267	331	43	,	,	PUNCT
easat-267	331	44	vol	vol	NOUN
easat-267	331	45	.	.	PROPN
easat-267	331	46	2	2	NUM
easat-267	331	47	,	,	PUNCT
easat-267	331	48	pp	pp	ADJ
easat-267	331	49	.	.	PUNCT
easat-267	332	1	229	229	NUM
easat-267	332	2	-	-	SYM
easat-267	332	3	235	235	NUM
easat-267	332	4	,	,	PUNCT
easat-267	332	5	2014	2014	NUM
easat-267	332	6	.	.	PUNCT
easat-267	333	1	https://doi.org/10.21106/ijma.29	https://doi.org/10.21106/ijma.29	X
easat-267	334	1	[	[	X
easat-267	334	2	38	38	NUM
easat-267	334	3	]	]	PUNCT
easat-267	334	4	r.	r.	PROPN
easat-267	334	5	balgir	balgir	PROPN
easat-267	334	6	,	,	PUNCT
easat-267	334	7	"	"	PUNCT
easat-267	334	8	reproductive	reproductive	ADJ
easat-267	334	9	outcome	outcome	NOUN
easat-267	334	10	in	in	ADP
easat-267	334	11	carrier	carrier	NOUN
easat-267	334	12	couples	couple	NOUN
easat-267	334	13	of	of	ADP
easat-267	334	14	β	β	X
easat-267	334	15	–	–	PUNCT
easat-267	334	16	thalassemia	thalassemia	NOUN
easat-267	334	17	disorders	disorder	NOUN
easat-267	334	18	in	in	ADP
easat-267	334	19	a	a	DET
easat-267	334	20	tertiary	tertiary	ADJ
easat-267	334	21	hospital	hospital	NOUN
easat-267	334	22	in	in	ADP
easat-267	334	23	central	central	ADJ
easat-267	334	24	india	india	PROPN
easat-267	334	25	,	,	PUNCT
easat-267	334	26	"	"	PUNCT
easat-267	334	27	thalassemia	thalassemia	NOUN
easat-267	334	28	reports	report	NOUN
easat-267	334	29	,	,	PUNCT
easat-267	334	30	vol	vol	NOUN
easat-267	334	31	.	.	PROPN
easat-267	334	32	4	4	NUM
easat-267	334	33	,	,	PUNCT
easat-267	334	34	pp	pp	ADJ
easat-267	334	35	.	.	PUNCT
easat-267	335	1	10	10	NUM
easat-267	335	2	-	-	SYM
easat-267	335	3	15	15	NUM
easat-267	335	4	,	,	PUNCT
easat-267	335	5	2014	2014	NUM
easat-267	335	6	.	.	PUNCT
easat-267	336	1	https://doi.org/10.4081/thal.2014.1907	https://doi.org/10.4081/thal.2014.1907	PROPN
easat-267	336	2	[	[	X
easat-267	336	3	39	39	NUM
easat-267	336	4	]	]	PUNCT
easat-267	336	5	g.	g.	NOUN
easat-267	336	6	pasvol	pasvol	PROPN
easat-267	336	7	,	,	PUNCT
easat-267	336	8	d.	d.	PROPN
easat-267	336	9	weatherall	weatherall	PROPN
easat-267	336	10	,	,	PUNCT
easat-267	336	11	and	and	CCONJ
easat-267	336	12	r.	r.	PROPN
easat-267	336	13	wilson	wilson	PROPN
easat-267	336	14	,	,	PUNCT
easat-267	336	15	"	"	PUNCT
easat-267	336	16	cellular	cellular	ADJ
easat-267	336	17	mechanism	mechanism	NOUN
easat-267	336	18	for	for	ADP
easat-267	336	19	the	the	DET
easat-267	336	20	protective	protective	ADJ
easat-267	336	21	effect	effect	NOUN
easat-267	336	22	of	of	ADP
easat-267	336	23	haemoglobin	haemoglobin	PROPN
easat-267	336	24	s	s	PART
easat-267	336	25	against	against	ADP
easat-267	336	26	p.	p.	NOUN
easat-267	336	27	falciparum	falciparum	PROPN
easat-267	336	28	malaria	malaria	NOUN
easat-267	336	29	,	,	PUNCT
easat-267	336	30	"	"	PUNCT
easat-267	336	31	nature	nature	NOUN
easat-267	336	32	,	,	PUNCT
easat-267	336	33	vol	vol	NOUN
easat-267	336	34	.	.	PROPN
easat-267	336	35	274	274	NUM
easat-267	336	36	,	,	PUNCT
easat-267	336	37	pp	pp	ADJ
easat-267	336	38	.	.	PUNCT
easat-267	337	1	701	701	NUM
easat-267	337	2	-	-	SYM
easat-267	337	3	703	703	NUM
easat-267	337	4	,	,	PUNCT
easat-267	337	5	1978	1978	NUM
easat-267	337	6	.	.	PUNCT
easat-267	338	1	https://doi.org/10.1038/274701a0	https://doi.org/10.1038/274701a0	PUNCT
easat-267	339	1	[	[	X
easat-267	339	2	40	40	NUM
easat-267	339	3	]	]	PUNCT
easat-267	339	4	p.	p.	NOUN
easat-267	339	5	duffy	duffy	PROPN
easat-267	339	6	and	and	CCONJ
easat-267	339	7	m.	m.	NOUN
easat-267	339	8	fried	fried	PROPN
easat-267	339	9	,	,	PUNCT
easat-267	339	10	"	"	PUNCT
easat-267	339	11	red	red	ADJ
easat-267	339	12	blood	blood	NOUN
easat-267	339	13	cells	cell	NOUN
easat-267	339	14	that	that	PRON
easat-267	339	15	do	do	VERB
easat-267	339	16	and	and	CCONJ
easat-267	339	17	red	red	ADJ
easat-267	339	18	blood	blood	NOUN
easat-267	339	19	cells	cell	NOUN
easat-267	339	20	that	that	PRON
easat-267	339	21	do	do	VERB
easat-267	339	22	n’t	not	PART
easat-267	339	23	:	:	PUNCT
easat-267	339	24	how	how	SCONJ
easat-267	339	25	to	to	PART
easat-267	339	26	resist	resist	VERB
easat-267	339	27	a	a	DET
easat-267	339	28	persistent	persistent	ADJ
easat-267	339	29	parasite	parasite	NOUN
easat-267	339	30	,	,	PUNCT
easat-267	339	31	"	"	PUNCT
easat-267	339	32	trends	trend	NOUN
easat-267	339	33	parasitol	parasitol	NOUN
easat-267	339	34	,	,	PUNCT
easat-267	339	35	vol	vol	NOUN
easat-267	339	36	.	.	PROPN
easat-267	340	1	22	22	NUM
easat-267	340	2	,	,	PUNCT
easat-267	340	3	pp	pp	ADJ
easat-267	340	4	.	.	PUNCT
easat-267	341	1	99	99	NUM
easat-267	341	2	-	-	SYM
easat-267	341	3	101	101	NUM
easat-267	341	4	,	,	PUNCT
easat-267	341	5	2006	2006	NUM
easat-267	341	6	.	.	PUNCT
easat-267	342	1	https://doi.org/10.1016/j.pt.2006.01.009	https://doi.org/10.1016/j.pt.2006.01.009	X
easat-267	343	1	[	[	X
easat-267	343	2	41	41	NUM
easat-267	343	3	]	]	PUNCT
easat-267	343	4	t.	t.	PROPN
easat-267	343	5	williams	williams	PROPN
easat-267	343	6	and	and	CCONJ
easat-267	343	7	d.	d.	PROPN
easat-267	343	8	weatherall	weatherall	PROPN
easat-267	343	9	,	,	PUNCT
easat-267	343	10	"	"	PUNCT
easat-267	343	11	world	world	NOUN
easat-267	343	12	distribution	distribution	NOUN
easat-267	343	13	,	,	PUNCT
easat-267	343	14	population	population	NOUN
easat-267	343	15	genetics	genetic	NOUN
easat-267	343	16	,	,	PUNCT
easat-267	343	17	and	and	CCONJ
easat-267	343	18	health	health	NOUN
easat-267	343	19	burden	burden	NOUN
easat-267	343	20	of	of	ADP
easat-267	343	21	the	the	DET
easat-267	343	22	hemoglobinopathies	hemoglobinopathy	NOUN
easat-267	343	23	,	,	PUNCT
easat-267	343	24	"	"	PUNCT
easat-267	343	25	cold	cold	ADJ
easat-267	343	26	spring	spring	NOUN
easat-267	343	27	harb	harb	PROPN
easat-267	343	28	perspect	perspect	PROPN
easat-267	343	29	med	me	VERB
easat-267	343	30	,	,	PUNCT
easat-267	343	31	vol	vol	NOUN
easat-267	343	32	.	.	PROPN
easat-267	343	33	2	2	NUM
easat-267	343	34	,	,	PUNCT
easat-267	343	35	p.	p.	NOUN
easat-267	343	36	a011692	a011692	NUM
easat-267	343	37	,	,	PUNCT
easat-267	343	38	2012	2012	NUM
easat-267	343	39	.	.	PUNCT
easat-267	344	1	https://doi.org/10.1101/cshperspect.a011692	https://doi.org/10.1101/cshperspect.a011692	PROPN
easat-267	345	1	[	[	X
easat-267	345	2	42	42	NUM
easat-267	345	3	]	]	PUNCT
easat-267	345	4	k.	k.	PROPN
easat-267	345	5	chotivanich	chotivanich	PROPN
easat-267	345	6	,	,	PUNCT
easat-267	345	7	r.	r.	PROPN
easat-267	345	8	udomsangpetch	udomsangpetch	PROPN
easat-267	345	9	,	,	PUNCT
easat-267	345	10	k.	k.	PROPN
easat-267	345	11	pattanapanyasat	pattanapanyasat	PROPN
easat-267	345	12	,	,	PUNCT
easat-267	345	13	w.	w.	PROPN
easat-267	345	14	chierakul	chierakul	PROPN
easat-267	345	15	,	,	PUNCT
easat-267	345	16	and	and	CCONJ
easat-267	345	17	j.	j.	PROPN
easat-267	345	18	simpson	simpson	PROPN
easat-267	345	19	,	,	PUNCT
easat-267	345	20	"	"	PUNCT
easat-267	345	21	hemoglobin	hemoglobin	NOUN
easat-267	345	22	e	e	NOUN
easat-267	345	23	:	:	PUNCT
easat-267	345	24	a	a	DET
easat-267	345	25	balanced	balanced	ADJ
easat-267	345	26	polymorphism	polymorphism	NOUN
easat-267	345	27	protective	protective	ADJ
easat-267	345	28	against	against	ADP
easat-267	345	29	high	high	ADJ
easat-267	345	30	parasitemias	parasitemia	NOUN
easat-267	345	31	and	and	CCONJ
easat-267	345	32	thus	thus	ADV
easat-267	345	33	severe	severe	ADJ
easat-267	345	34	p	p	ADJ
easat-267	345	35	falciparum	falciparum	ADJ
easat-267	345	36	malaria	malaria	NOUN
easat-267	345	37	,	,	PUNCT
easat-267	345	38	"	"	PUNCT
easat-267	345	39	blood	blood	NOUN
easat-267	345	40	,	,	PUNCT
easat-267	345	41	vol	vol	NOUN
easat-267	345	42	.	.	PROPN
easat-267	345	43	100	100	NUM
easat-267	345	44	,	,	PUNCT
easat-267	345	45	pp	pp	ADJ
easat-267	345	46	.	.	PUNCT
easat-267	345	47	11721176	11721176	NUM
easat-267	345	48	,	,	PUNCT
easat-267	345	49	2002	2002	NUM
easat-267	345	50	.	.	PUNCT
easat-267	346	1	https://doi.org/10.1182/blood.v100.4.1172.h81602001172_1172_1176	https://doi.org/10.1182/blood.v100.4.1172.h81602001172_1172_1176	X
easat-267	347	1	[	[	X
easat-267	347	2	43	43	NUM
easat-267	347	3	]	]	X
easat-267	347	4	r.	r.	PROPN
easat-267	347	5	balgir	balgir	PROPN
easat-267	347	6	,	,	PUNCT
easat-267	347	7	"	"	PUNCT
easat-267	347	8	red	red	ADJ
easat-267	347	9	cell	cell	NOUN
easat-267	347	10	genetic	genetic	ADJ
easat-267	347	11	markers	marker	NOUN
easat-267	347	12	in	in	ADP
easat-267	347	13	malarial	malarial	ADJ
easat-267	347	14	susceptibility	susceptibility	NOUN
easat-267	347	15	and	and	CCONJ
easat-267	347	16	selective	selective	ADJ
easat-267	347	17	advantage	advantage	NOUN
easat-267	347	18	hypothesis	hypothesis	NOUN
easat-267	347	19	,	,	PUNCT
easat-267	347	20	"	"	PUNCT
easat-267	347	21	the	the	DET
easat-267	347	22	online	online	ADJ
easat-267	347	23	journal	journal	NOUN
easat-267	347	24	of	of	ADP
easat-267	347	25	health	health	PROPN
easat-267	347	26	and	and	CCONJ
easat-267	347	27	allied	ally	VERB
easat-267	347	28	sciences	science	NOUN
easat-267	347	29	,	,	PUNCT
easat-267	347	30	vol	vol	NOUN
easat-267	347	31	.	.	PROPN
easat-267	347	32	12	12	NUM
easat-267	347	33	,	,	PUNCT
easat-267	347	34	p.	p.	NOUN
easat-267	347	35	6	6	NUM
easat-267	347	36	,	,	PUNCT
easat-267	347	37	2013	2013	NUM
easat-267	347	38	.	.	PUNCT
easat-267	348	1	[	[	X
easat-267	348	2	44	44	NUM
easat-267	348	3	]	]	PUNCT
easat-267	348	4	r.	r.	PROPN
easat-267	348	5	balgir	balgir	PROPN
easat-267	348	6	,	,	PUNCT
easat-267	348	7	"	"	PUNCT
easat-267	348	8	is	be	AUX
easat-267	348	9	hemoglobin	hemoglobin	NOUN
easat-267	348	10	e	e	NOUN
easat-267	348	11	gene	gene	NOUN
easat-267	348	12	widely	widely	ADV
easat-267	348	13	spread	spread	VERB
easat-267	348	14	in	in	ADP
easat-267	348	15	the	the	DET
easat-267	348	16	state	state	NOUN
easat-267	348	17	of	of	ADP
easat-267	348	18	madhya	madhya	PROPN
easat-267	348	19	pradesh	pradesh	PROPN
easat-267	348	20	in	in	ADP
easat-267	348	21	central	central	PROPN
easat-267	348	22	india	india	PROPN
easat-267	348	23	?	?	PUNCT
easat-267	349	1	evidence	evidence	NOUN
easat-267	349	2	from	from	ADP
easat-267	349	3	five	five	NUM
easat-267	349	4	typical	typical	ADJ
easat-267	349	5	families	family	NOUN
easat-267	349	6	,	,	PUNCT
easat-267	349	7	"	"	PUNCT
easat-267	349	8	mediterranean	mediterranean	PROPN
easat-267	349	9	journal	journal	PROPN
easat-267	349	10	of	of	ADP
easat-267	349	11	hematology	hematology	NOUN
easat-267	349	12	and	and	CCONJ
easat-267	349	13	infectious	infectious	ADJ
easat-267	349	14	diseases	disease	NOUN
easat-267	349	15	,	,	PUNCT
easat-267	349	16	vol	vol	NOUN
easat-267	349	17	.	.	PROPN
easat-267	349	18	6	6	NUM
easat-267	349	19	,	,	PUNCT
easat-267	349	20	p.	p.	NOUN
easat-267	349	21	e2014060	e2014060	PROPN
easat-267	349	22	,	,	PUNCT
easat-267	349	23	2014	2014	NUM
easat-267	349	24	.	.	PUNCT
easat-267	350	1	https://doi.org/10.4084/mjhid.2014.060	https://doi.org/10.4084/mjhid.2014.060	PROPN
easat-267	350	2	[	[	X
easat-267	350	3	45	45	NUM
easat-267	350	4	]	]	PUNCT
easat-267	350	5	b.	b.	PROPN
easat-267	350	6	genton	genton	PROPN
easat-267	350	7	,	,	PUNCT
easat-267	350	8	f.	f.	PROPN
easat-267	350	9	al	al	PROPN
easat-267	350	10	-	-	PUNCT
easat-267	350	11	yaman	yaman	PROPN
easat-267	350	12	,	,	PUNCT
easat-267	350	13	c.	c.	PROPN
easat-267	350	14	mgone	mgone	PROPN
easat-267	350	15	,	,	PUNCT
easat-267	350	16	n.	n.	PROPN
easat-267	350	17	alexander	alexander	NOUN
easat-267	350	18	,	,	PUNCT
easat-267	350	19	and	and	CCONJ
easat-267	350	20	m.	m.	PROPN
easat-267	350	21	paniu	paniu	PROPN
easat-267	350	22	,	,	PUNCT
easat-267	350	23	"	"	PUNCT
easat-267	350	24	ovalocytosis	ovalocytosis	NOUN
easat-267	350	25	and	and	CCONJ
easat-267	350	26	cerebral	cerebral	ADJ
easat-267	350	27	malaria	malaria	NOUN
easat-267	350	28	,	,	PUNCT
easat-267	350	29	"	"	PUNCT
easat-267	350	30	nature	nature	NOUN
easat-267	350	31	,	,	PUNCT
easat-267	350	32	vol	vol	NOUN
easat-267	350	33	.	.	PROPN
easat-267	350	34	378	378	NUM
easat-267	350	35	,	,	PUNCT
easat-267	350	36	pp	pp	ADJ
easat-267	350	37	.	.	PUNCT
easat-267	351	1	564	564	NUM
easat-267	351	2	-	-	SYM
easat-267	351	3	565	565	NUM
easat-267	351	4	,	,	PUNCT
easat-267	351	5	1995	1995	NUM
easat-267	351	6	.	.	PUNCT
easat-267	352	1	https://doi.org/10.1038/378564a0	https://doi.org/10.1038/378564a0	X
easat-267	353	1	[	[	X
easat-267	353	2	46	46	NUM
easat-267	353	3	]	]	X
easat-267	353	4	p.	p.	NOUN
easat-267	353	5	gallagher	gallagher	PROPN
easat-267	353	6	,	,	PUNCT
easat-267	353	7	"	"	PUNCT
easat-267	353	8	red	red	ADJ
easat-267	353	9	cell	cell	NOUN
easat-267	353	10	membrane	membrane	NOUN
easat-267	353	11	disorders	disorder	NOUN
easat-267	353	12	,	,	PUNCT
easat-267	353	13	"	"	PUNCT
easat-267	353	14	hematol	hematol	NOUN
easat-267	353	15	am	be	AUX
easat-267	353	16	soc	soc	NOUN
easat-267	353	17	hematol	hematol	PROPN
easat-267	353	18	edu	edu	PROPN
easat-267	353	19	program	program	PROPN
easat-267	353	20	,	,	PUNCT
easat-267	353	21	vol	vol	NOUN
easat-267	353	22	.	.	PROPN
easat-267	353	23	1	1	NUM
easat-267	353	24	,	,	PUNCT
easat-267	353	25	pp	pp	ADJ
easat-267	353	26	.	.	PUNCT
easat-267	354	1	13	13	NUM
easat-267	354	2	-	-	SYM
easat-267	354	3	18	18	NUM
easat-267	354	4	,	,	PUNCT
easat-267	354	5	2005	2005	NUM
easat-267	354	6	.	.	PUNCT
easat-267	355	1	[	[	X
easat-267	355	2	47	47	NUM
easat-267	355	3	]	]	X
easat-267	355	4	c.	c.	PROPN
easat-267	355	5	ruwende	ruwende	PROPN
easat-267	355	6	,	,	PUNCT
easat-267	355	7	s.	s.	PROPN
easat-267	355	8	khoo	khoo	PROPN
easat-267	355	9	,	,	PUNCT
easat-267	355	10	r.	r.	PROPN
easat-267	355	11	snow	snow	PROPN
easat-267	355	12	,	,	PUNCT
easat-267	355	13	s.	s.	PROPN
easat-267	355	14	yates	yates	PROPN
easat-267	355	15	,	,	PUNCT
easat-267	355	16	and	and	CCONJ
easat-267	355	17	d.	d.	PROPN
easat-267	355	18	kwiatkowski	kwiatkowski	PROPN
easat-267	355	19	,	,	PUNCT
easat-267	355	20	"	"	PUNCT
easat-267	355	21	natural	natural	ADJ
easat-267	355	22	selection	selection	NOUN
easat-267	355	23	of	of	ADP
easat-267	355	24	hemiand	hemiand	NOUN
easat-267	355	25	heterozygotes	heterozygote	NOUN
easat-267	355	26	for	for	ADP
easat-267	355	27	g6pd	g6pd	NOUN
easat-267	355	28	deficiency	deficiency	NOUN
easat-267	355	29	in	in	ADP
easat-267	355	30	africa	africa	PROPN
easat-267	355	31	by	by	ADP
easat-267	355	32	resistance	resistance	NOUN
easat-267	355	33	to	to	ADP
easat-267	355	34	severe	severe	ADJ
easat-267	355	35	malaria	malaria	NOUN
easat-267	355	36	,	,	PUNCT
easat-267	355	37	"	"	PUNCT
easat-267	355	38	nature	nature	NOUN
easat-267	355	39	,	,	PUNCT
easat-267	355	40	vol	vol	NOUN
easat-267	355	41	.	.	PROPN
easat-267	355	42	376	376	NUM
easat-267	355	43	,	,	PUNCT
easat-267	355	44	pp	pp	ADJ
easat-267	355	45	.	.	PUNCT
easat-267	356	1	246	246	NUM
easat-267	356	2	-	-	SYM
easat-267	356	3	249	249	NUM
easat-267	356	4	,	,	PUNCT
easat-267	356	5	1995	1995	NUM
easat-267	356	6	.	.	PUNCT
easat-267	357	1	https://doi.org/10.1038/376246a0	https://doi.org/10.1038/376246a0	PUNCT
easat-267	358	1	[	[	X
easat-267	358	2	48	48	NUM
easat-267	358	3	]	]	PUNCT
easat-267	358	4	a.	a.	NOUN
easat-267	358	5	guindo	guindo	PROPN
easat-267	358	6	,	,	PUNCT
easat-267	358	7	r.	r.	PROPN
easat-267	358	8	fairhurst	fairhurst	PROPN
easat-267	358	9	,	,	PUNCT
easat-267	358	10	o.	o.	NOUN
easat-267	358	11	doumbo	doumbo	NOUN
easat-267	358	12	,	,	PUNCT
easat-267	358	13	t.	t.	NOUN
easat-267	358	14	wellems	wellem	NOUN
easat-267	358	15	,	,	PUNCT
easat-267	358	16	and	and	CCONJ
easat-267	358	17	d.	d.	PROPN
easat-267	358	18	x.	x.	PROPN
easat-267	358	19	diallo	diallo	PROPN
easat-267	358	20	,	,	PUNCT
easat-267	358	21	"	"	PUNCT
easat-267	358	22	linked	link	VERB
easat-267	358	23	g6pd	g6pd	NOUN
easat-267	358	24	deficiency	deficiency	NOUN
easat-267	358	25	protects	protect	VERB
easat-267	358	26	hemizygous	hemizygous	ADJ
easat-267	358	27	males	male	NOUN
easat-267	358	28	but	but	CCONJ
easat-267	358	29	not	not	PART
easat-267	358	30	heterozygous	heterozygous	ADJ
easat-267	358	31	females	female	NOUN
easat-267	358	32	against	against	ADP
easat-267	358	33	severe	severe	ADJ
easat-267	358	34	malaria	malaria	NOUN
easat-267	358	35	,	,	PUNCT
easat-267	358	36	"	"	PUNCT
easat-267	358	37	plos	plos	PROPN
easat-267	358	38	med	med	PROPN
easat-267	358	39	,	,	PUNCT
easat-267	358	40	vol	vol	NOUN
easat-267	358	41	.	.	PROPN
easat-267	359	1	4	4	NUM
easat-267	359	2	,	,	PUNCT
easat-267	359	3	pp	pp	ADJ
easat-267	359	4	.	.	PUNCT
easat-267	360	1	0516	0516	NUM
easat-267	360	2	-	-	SYM
easat-267	360	3	0522	0522	NUM
easat-267	360	4	,	,	PUNCT
easat-267	360	5	2007	2007	NUM
easat-267	360	6	.	.	PUNCT
easat-267	361	1	https://doi.org/10.1371/journal.pmed.0040066	https://doi.org/10.1371/journal.pmed.0040066	PROPN
easat-267	362	1	[	[	X
easat-267	362	2	49	49	NUM
easat-267	362	3	]	]	PUNCT
easat-267	362	4	l.	l.	PROPN
easat-267	362	5	luzzatto	luzzatto	PROPN
easat-267	362	6	,	,	PUNCT
easat-267	362	7	e.	e.	PROPN
easat-267	362	8	usanga	usanga	PROPN
easat-267	362	9	,	,	PUNCT
easat-267	362	10	and	and	CCONJ
easat-267	362	11	s.	s.	PROPN
easat-267	362	12	reddy	reddy	PROPN
easat-267	362	13	,	,	PUNCT
easat-267	362	14	"	"	PUNCT
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easat-267	362	16	6	6	NUM
easat-267	362	17	-	-	PUNCT
easat-267	362	18	phosphate	phosphate	NOUN
easat-267	362	19	dehydrogenase	dehydrogenase	NOUN
easat-267	362	20	deficient	deficient	ADJ
easat-267	362	21	red	red	ADJ
easat-267	362	22	cells	cell	NOUN
easat-267	362	23	:	:	PUNCT
easat-267	362	24	resistance	resistance	NOUN
easat-267	362	25	to	to	ADP
easat-267	362	26	infection	infection	NOUN
easat-267	362	27	by	by	ADP
easat-267	362	28	malarial	malarial	ADJ
easat-267	362	29	parasites	parasite	NOUN
easat-267	362	30	,	,	PUNCT
easat-267	362	31	"	"	PUNCT
easat-267	362	32	science	science	NOUN
easat-267	362	33	,	,	PUNCT
easat-267	362	34	vol	vol	NOUN
easat-267	362	35	.	.	NOUN
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easat-267	362	37	,	,	PUNCT
easat-267	362	38	pp	pp	ADV
easat-267	362	39	.	.	PUNCT
easat-267	362	40	839	839	NUM
easat-267	362	41	-	-	SYM
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easat-267	362	43	,	,	PUNCT
easat-267	362	44	1969	1969	NUM
easat-267	362	45	.	.	PUNCT
easat-267	363	1	http://dx.doi.org/10.1126/science.164.3881.839	http://dx.doi.org/10.1126/science.164.3881.839	NOUN
easat-267	364	1	[	[	X
easat-267	364	2	50	50	NUM
easat-267	364	3	]	]	PUNCT
easat-267	364	4	r.	r.	PROPN
easat-267	364	5	balgir	balgir	PROPN
easat-267	364	6	,	,	PUNCT
easat-267	364	7	"	"	PUNCT
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easat-267	364	9	of	of	ADP
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easat-267	364	12	to	to	ADP
easat-267	364	13	community	community	NOUN
easat-267	364	14	inbreeding	inbreede	VERB
easat-267	364	15	,	,	PUNCT
easat-267	364	16	homozygosis	homozygosis	NOUN
easat-267	364	17	,	,	PUNCT
easat-267	364	18	and	and	CCONJ
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easat-267	364	20	wastage	wastage	NOUN
easat-267	364	21	for	for	ADP
easat-267	364	22	recessively	recessively	ADV
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easat-267	364	24	genetic	genetic	ADJ
easat-267	364	25	disorders	disorder	NOUN
easat-267	364	26	in	in	ADP
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easat-267	364	28	pradesh	pradesh	PROPN
easat-267	364	29	,	,	PUNCT
easat-267	364	30	india	india	PROPN
easat-267	364	31	,	,	PUNCT
easat-267	364	32	"	"	PUNCT
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easat-267	364	34	journal	journal	PROPN
easat-267	364	35	of	of	ADP
easat-267	364	36	hematology	hematology	NOUN
easat-267	364	37	and	and	CCONJ
easat-267	364	38	infectious	infectious	ADJ
easat-267	364	39	diseases	disease	NOUN
easat-267	364	40	,	,	PUNCT
easat-267	364	41	vol	vol	NOUN
easat-267	364	42	.	.	PROPN
easat-267	364	43	5	5	NUM
easat-267	364	44	,	,	PUNCT
easat-267	364	45	p.	p.	NOUN
easat-267	364	46	e2013063	e2013063	NOUN
easat-267	364	47	,	,	PUNCT
easat-267	364	48	2013	2013	NUM
easat-267	364	49	.	.	PUNCT
easat-267	365	1	https://dx.doi.org/10.4084%2fmjhid.2013.063	https://dx.doi.org/10.4084%2fmjhid.2013.063	PROPN
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easat-267	366	2	51	51	NUM
easat-267	366	3	]	]	X
easat-267	366	4	r.	r.	PROPN
easat-267	366	5	balgir	balgir	PROPN
easat-267	366	6	,	,	PUNCT
easat-267	366	7	"	"	PUNCT
easat-267	366	8	impact	impact	NOUN
easat-267	366	9	of	of	ADP
easat-267	366	10	consanguinity	consanguinity	NOUN
easat-267	366	11	and	and	CCONJ
easat-267	366	12	inbreeding	inbreede	VERB
easat-267	366	13	on	on	ADP
easat-267	366	14	homozygosis	homozygosis	NOUN
easat-267	366	15	of	of	ADP
easat-267	366	16	recessively	recessively	ADV
easat-267	366	17	inherited	inherit	VERB
easat-267	366	18	genetic	genetic	ADJ
easat-267	366	19	disorders	disorder	NOUN
easat-267	366	20	among	among	ADP
easat-267	366	21	tribes	tribe	NOUN
easat-267	366	22	of	of	ADP
easat-267	366	23	central	central	ADJ
easat-267	366	24	india	india	PROPN
easat-267	366	25	:	:	PUNCT
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easat-267	366	27	most	most	ADV
easat-267	366	28	detrimental	detrimental	ADJ
easat-267	366	29	and	and	CCONJ
easat-267	366	30	widely	widely	ADV
easat-267	366	31	practiced	practice	VERB
easat-267	366	32	evil	evil	NOUN
easat-267	366	33	,	,	PUNCT
easat-267	366	34	"	"	PUNCT
easat-267	366	35	trib	trib	PROPN
easat-267	366	36	heal	heal	NOUN
easat-267	366	37	bull	bull	NOUN
easat-267	366	38	,	,	PUNCT
easat-267	366	39	vol	vol	NOUN
easat-267	366	40	.	.	PROPN
easat-267	366	41	21	21	NUM
easat-267	366	42	,	,	PUNCT
easat-267	366	43	pp	pp	ADJ
easat-267	366	44	.	.	PUNCT
easat-267	367	1	18	18	NUM
easat-267	367	2	-	-	SYM
easat-267	367	3	24	24	NUM
easat-267	367	4	,	,	PUNCT
easat-267	367	5	2014	2014	NUM
easat-267	367	6	.	.	PUNCT
easat-267	368	1	https://doi.org/10.1080/09723757.2003.11885854	https://doi.org/10.1080/09723757.2003.11885854	PROPN
easat-267	369	1	https://doi.org/10.1086/429832	https://doi.org/10.1086/429832	NOUN
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easat-267	369	5	https://doi.org/10.21106/ijma.29	https://doi.org/10.21106/ijma.29	PROPN
easat-267	369	6	https://doi.org/10.4081/thal.2014.1907	https://doi.org/10.4081/thal.2014.1907	PROPN
easat-267	369	7	https://doi.org/10.1038/274701a0	https://doi.org/10.1038/274701a0	PROPN
easat-267	369	8	https://doi.org/10.1016/j.pt.2006.01.009	https://doi.org/10.1016/j.pt.2006.01.009	PROPN
easat-267	369	9	https://doi.org/10.1101/cshperspect.a011692	https://doi.org/10.1101/cshperspect.a011692	PROPN
easat-267	369	10	https://doi.org/10.1182/blood.v100.4.1172.h81602001172_1172_1176	https://doi.org/10.1182/blood.v100.4.1172.h81602001172_1172_1176	PROPN
easat-267	369	11	https://doi.org/10.4084/mjhid.2014.060	https://doi.org/10.4084/mjhid.2014.060	NOUN
easat-267	369	12	https://doi.org/10.1038/378564a0	https://doi.org/10.1038/378564a0	X
easat-267	369	13	https://doi.org/10.1038/376246a0	https://doi.org/10.1038/376246a0	ADP
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easat-267	369	15	http://dx.doi.org/10.1126/science.164.3881.839	http://dx.doi.org/10.1126/science.164.3881.839	NOUN
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