id	sid	tid	token	lemma	pos
easat-284	1	1	edelweiss	edelweiss	PROPN
easat-284	1	2	applied	apply	VERB
easat-284	1	3	science	science	NOUN
easat-284	1	4	and	and	CCONJ
easat-284	1	5	technology	technology	NOUN
easat-284	1	6	issn	issn	PROPN
easat-284	1	7	:	:	PUNCT
easat-284	1	8	2576	2576	NUM
easat-284	1	9	-	-	SYM
easat-284	1	10	8484	8484	NUM
easat-284	1	11	vol	vol	NOUN
easat-284	1	12	.	.	PROPN
easat-284	2	1	4	4	NUM
easat-284	2	2	,	,	PUNCT
easat-284	2	3	no	no	INTJ
easat-284	2	4	.	.	NOUN
easat-284	2	5	1	1	NUM
easat-284	2	6	,	,	PUNCT
easat-284	2	7	67	67	NUM
easat-284	2	8	-	-	SYM
easat-284	2	9	73	73	NUM
easat-284	2	10	2020	2020	NUM
easat-284	2	11	doi	doi	NOUN
easat-284	2	12	:	:	PUNCT
easat-284	2	13	10.33805/2576	10.33805/2576	NUM
easat-284	2	14	-	-	SYM
easat-284	2	15	8484.184	8484.184	NUM
easat-284	2	16	©	©	PROPN
easat-284	2	17	2020	2020	NUM
easat-284	2	18	by	by	ADP
easat-284	2	19	the	the	DET
easat-284	2	20	author	author	NOUN
easat-284	2	21	©	©	PROPN
easat-284	2	22	2020	2020	NUM
easat-284	2	23	by	by	ADP
easat-284	2	24	the	the	DET
easat-284	2	25	author	author	NOUN
easat-284	2	26	history	history	NOUN
easat-284	2	27	:	:	PUNCT
easat-284	2	28	received	receive	VERB
easat-284	2	29	:	:	PUNCT
easat-284	2	30	25	25	NUM
easat-284	2	31	november	november	PROPN
easat-284	2	32	2020	2020	NUM
easat-284	2	33	;	;	PUNCT
easat-284	2	34	accepted	accept	VERB
easat-284	2	35	:	:	PUNCT
easat-284	2	36	09	09	NUM
easat-284	2	37	december	december	PROPN
easat-284	2	38	2020	2020	NUM
easat-284	2	39	;	;	PUNCT
easat-284	2	40	published	publish	VERB
easat-284	2	41	:	:	PUNCT
easat-284	2	42	21	21	NUM
easat-284	2	43	december	december	PROPN
easat-284	2	44	2020	2020	NUM
easat-284	2	45	*	*	PUNCT
easat-284	2	46	correspondence	correspondence	NOUN
easat-284	2	47	:	:	PUNCT
easat-284	3	1	fornasaripiermaria@gmail.com	fornasaripiermaria@gmail.com	X
easat-284	3	2	sars	sars	PROPN
easat-284	3	3	-	-	PUNCT
easat-284	3	4	cov-2	cov-2	PART
easat-284	3	5	infection	infection	NOUN
easat-284	3	6	is	be	AUX
easat-284	3	7	protease	protease	NOUN
easat-284	3	8	-	-	PUNCT
easat-284	3	9	dependent	dependent	ADJ
easat-284	3	10	and	and	CCONJ
easat-284	3	11	induces	induce	VERB
easat-284	3	12	neutrophils	neutrophil	NOUN
easat-284	3	13	“	"	PUNCT
easat-284	3	14	proteolytic	proteolytic	ADJ
easat-284	3	15	storm	storm	NOUN
easat-284	3	16	”	"	PUNCT
easat-284	3	17	triggering	trigger	VERB
easat-284	3	18	clinical	clinical	ADJ
easat-284	3	19	worsening	worsening	NOUN
easat-284	3	20	and	and	CCONJ
easat-284	3	21	viral	viral	ADJ
easat-284	3	22	sepsis	sepsis	NOUN
easat-284	3	23	.	.	PUNCT
easat-284	4	1	proteolysis	proteolysis	NOUN
easat-284	4	2	and	and	CCONJ
easat-284	4	3	inhibitors	inhibitor	NOUN
easat-284	4	4	of	of	ADP
easat-284	4	5	neutrophil	neutrophil	ADJ
easat-284	4	6	release	release	NOUN
easat-284	4	7	can	can	AUX
easat-284	4	8	prevent	prevent	VERB
easat-284	4	9	and	and	CCONJ
easat-284	4	10	treat	treat	VERB
easat-284	4	11	covid-19	covid-19	PROPN
easat-284	4	12	pier	pier	PROPN
easat-284	4	13	maria	maria	PROPN
easat-284	4	14	fornasari	fornasari	PROPN
easat-284	4	15	regen	regen	PROPN
easat-284	4	16	health	health	PROPN
easat-284	4	17	solutions	solution	NOUN
easat-284	4	18	research	research	NOUN
easat-284	4	19	unit	unit	NOUN
easat-284	4	20	,	,	PUNCT
easat-284	4	21	bologna	bologna	PROPN
easat-284	4	22	,	,	PUNCT
easat-284	4	23	italy	italy	PROPN
easat-284	4	24	;	;	PUNCT
easat-284	4	25	fornasaripiermaria@gmail.com	fornasaripiermaria@gmail.com	X
easat-284	4	26	(	(	PUNCT
easat-284	4	27	p.m.f	p.m.f	NOUN
easat-284	4	28	)	)	PUNCT
easat-284	4	29	.	.	PUNCT
easat-284	5	1	abstract	abstract	NOUN
easat-284	5	2	:	:	PUNCT
easat-284	5	3	based	base	VERB
easat-284	5	4	on	on	ADP
easat-284	5	5	chinese	chinese	PROPN
easat-284	5	6	cdcp	cdcp	VERB
easat-284	5	7	report	report	NOUN
easat-284	5	8	on	on	ADP
easat-284	5	9	covid-19	covid-19	PROPN
easat-284	5	10	,	,	PUNCT
easat-284	5	11	14	14	NUM
easat-284	5	12	%	%	NOUN
easat-284	5	13	of	of	ADP
easat-284	5	14	patients	patient	NOUN
easat-284	5	15	presented	present	VERB
easat-284	5	16	severe	severe	ADJ
easat-284	5	17	disease	disease	NOUN
easat-284	5	18	and	and	CCONJ
easat-284	5	19	5	5	NUM
easat-284	5	20	%	%	NOUN
easat-284	5	21	critical	critical	ADJ
easat-284	5	22	conditions	condition	NOUN
easat-284	5	23	.	.	PUNCT
easat-284	6	1	the	the	DET
easat-284	6	2	average	average	ADJ
easat-284	6	3	case	case	NOUN
easat-284	6	4	-	-	PUNCT
easat-284	6	5	fatality	fatality	NOUN
easat-284	6	6	rate	rate	NOUN
easat-284	6	7	was	be	AUX
easat-284	6	8	2.3	2.3	NUM
easat-284	6	9	%	%	NOUN
easat-284	6	10	,	,	PUNCT
easat-284	6	11	but	but	CCONJ
easat-284	6	12	mortality	mortality	NOUN
easat-284	6	13	was	be	AUX
easat-284	6	14	as	as	ADV
easat-284	6	15	high	high	ADJ
easat-284	6	16	as	as	ADP
easat-284	6	17	49	49	NUM
easat-284	6	18	%	%	NOUN
easat-284	6	19	in	in	ADP
easat-284	6	20	patients	patient	NOUN
easat-284	6	21	with	with	ADP
easat-284	6	22	critical	critical	ADJ
easat-284	6	23	illness	illness	NOUN
easat-284	6	24	.	.	PUNCT
easat-284	7	1	serious	serious	ADJ
easat-284	7	2	life	life	NOUN
easat-284	7	3	threatening	threaten	VERB
easat-284	7	4	thromboembolic	thromboembolic	ADJ
easat-284	7	5	complications	complication	NOUN
easat-284	7	6	have	have	AUX
easat-284	7	7	been	be	AUX
easat-284	7	8	found	find	VERB
easat-284	7	9	in	in	ADP
easat-284	7	10	71.4	71.4	NUM
easat-284	7	11	%	%	NOUN
easat-284	7	12	of	of	ADP
easat-284	7	13	non	non	NOUN
easat-284	7	14	-	-	NOUN
easat-284	7	15	survivors	survivor	NOUN
easat-284	7	16	and	and	CCONJ
easat-284	7	17	micro	micro	ADJ
easat-284	7	18	/	/	PROPN
easat-284	7	19	macro	macro	ADJ
easat-284	7	20	angiopathic	angiopathic	ADJ
easat-284	7	21	coagulopathy	coagulopathy	ADJ
easat-284	7	22	has	have	AUX
easat-284	7	23	been	be	AUX
easat-284	7	24	found	find	VERB
easat-284	7	25	,	,	PUNCT
easat-284	7	26	at	at	ADP
easat-284	7	27	autopsy	autopsy	ADJ
easat-284	7	28	also	also	ADV
easat-284	7	29	,	,	PUNCT
easat-284	7	30	with	with	ADP
easat-284	7	31	highly	highly	ADV
easat-284	7	32	increased	increase	VERB
easat-284	7	33	neutrophil	neutrophil	ADJ
easat-284	7	34	number	number	NOUN
easat-284	7	35	,	,	PUNCT
easat-284	7	36	fibrinogen	fibrinogen	NOUN
easat-284	7	37	,	,	PUNCT
easat-284	7	38	concentrations	concentration	NOUN
easat-284	7	39	of	of	ADP
easat-284	7	40	d	d	NOUN
easat-284	7	41	-	-	PUNCT
easat-284	7	42	dimer	dimer	NOUN
easat-284	7	43	and	and	CCONJ
easat-284	7	44	fdps	fdps	NOUN
easat-284	7	45	and	and	CCONJ
easat-284	7	46	nets	net	NOUN
easat-284	7	47	,	,	PUNCT
easat-284	7	48	atiii	atiii	NOUN
easat-284	7	49	decrease	decrease	NOUN
easat-284	7	50	and	and	CCONJ
easat-284	7	51	normal	normal	ADJ
easat-284	7	52	number	number	NOUN
easat-284	7	53	of	of	ADP
easat-284	7	54	platelets	platelet	NOUN
easat-284	7	55	.	.	PUNCT
easat-284	8	1	a	a	DET
easat-284	8	2	cytokine	cytokine	ADJ
easat-284	8	3	storm	storm	NOUN
easat-284	8	4	and	and	CCONJ
easat-284	8	5	interaction	interaction	NOUN
easat-284	8	6	between	between	ADP
easat-284	8	7	inflammation	inflammation	NOUN
easat-284	8	8	and	and	CCONJ
easat-284	8	9	coagulation	coagulation	NOUN
easat-284	8	10	has	have	AUX
easat-284	8	11	been	be	AUX
easat-284	8	12	advocated	advocate	VERB
easat-284	8	13	as	as	ADP
easat-284	8	14	explanation	explanation	NOUN
easat-284	8	15	of	of	ADP
easat-284	8	16	hypercoagulability	hypercoagulability	NOUN
easat-284	8	17	.	.	PUNCT
easat-284	9	1	it	it	PRON
easat-284	9	2	has	have	AUX
easat-284	9	3	been	be	AUX
easat-284	9	4	shown	show	VERB
easat-284	9	5	that	that	SCONJ
easat-284	9	6	sars	sar	NOUN
easat-284	9	7	-	-	PUNCT
easat-284	9	8	cov-2	cov-2	PART
easat-284	9	9	infection	infection	NOUN
easat-284	9	10	of	of	ADP
easat-284	9	11	alveolar	alveolar	ADJ
easat-284	9	12	cells	cell	NOUN
easat-284	9	13	is	be	AUX
easat-284	9	14	driven	drive	VERB
easat-284	9	15	by	by	ADP
easat-284	9	16	the	the	DET
easat-284	9	17	s	s	NOUN
easat-284	9	18	-	-	NOUN
easat-284	9	19	protein	protein	NOUN
easat-284	9	20	by	by	ADP
easat-284	9	21	engaging	engage	VERB
easat-284	9	22	ace2	ace2	NOUN
easat-284	9	23	and	and	CCONJ
easat-284	9	24	tmprss2	tmprss2	ADP
easat-284	9	25	cell	cell	NOUN
easat-284	9	26	receptors	receptor	NOUN
easat-284	9	27	.	.	PUNCT
easat-284	10	1	whose	whose	DET
easat-284	10	2	activation	activation	NOUN
easat-284	10	3	depends	depend	VERB
easat-284	10	4	on	on	ADP
easat-284	10	5	the	the	DET
easat-284	10	6	activity	activity	NOUN
easat-284	10	7	of	of	ADP
easat-284	10	8	various	various	ADJ
easat-284	10	9	host	host	NOUN
easat-284	10	10	proteases	protease	NOUN
easat-284	10	11	.	.	PUNCT
easat-284	11	1	full	full	ADJ
easat-284	11	2	inhibition	inhibition	NOUN
easat-284	11	3	of	of	ADP
easat-284	11	4	sars	sar	NOUN
easat-284	11	5	-	-	PUNCT
easat-284	11	6	cov-2	cov-2	PART
easat-284	11	7	entry	entry	NOUN
easat-284	11	8	was	be	AUX
easat-284	11	9	observed	observe	VERB
easat-284	11	10	when	when	SCONJ
easat-284	11	11	serine	serine	ADJ
easat-284	11	12	proteases	protease	NOUN
easat-284	11	13	inhibitor	inhibitor	NOUN
easat-284	11	14	camostat	camostat	NOUN
easat-284	11	15	mesylate	mesylate	NOUN
easat-284	11	16	was	be	AUX
easat-284	11	17	coupled	couple	VERB
easat-284	11	18	with	with	ADP
easat-284	11	19	cathepsin	cathepsin	NOUN
easat-284	11	20	b	b	PROPN
easat-284	11	21	/	/	SYM
easat-284	11	22	l	l	NOUN
easat-284	11	23	inhibitor	inhibitor	NOUN
easat-284	11	24	e-64d	e-64d	PRON
easat-284	11	25	.	.	PUNCT
easat-284	12	1	in	in	ADP
easat-284	12	2	addition	addition	NOUN
easat-284	12	3	multiple	multiple	ADJ
easat-284	12	4	proteases	protease	NOUN
easat-284	12	5	are	be	AUX
easat-284	12	6	involved	involve	VERB
easat-284	12	7	in	in	ADP
easat-284	12	8	host	host	NOUN
easat-284	12	9	immune	immune	ADJ
easat-284	12	10	response	response	NOUN
easat-284	12	11	against	against	ADP
easat-284	12	12	viral	viral	ADJ
easat-284	12	13	invasion	invasion	NOUN
easat-284	12	14	and	and	CCONJ
easat-284	12	15	immunopathology	immunopathology	NOUN
easat-284	12	16	related	relate	VERB
easat-284	12	17	to	to	ADP
easat-284	12	18	imbalanced	imbalanced	ADJ
easat-284	12	19	immune	immune	ADJ
easat-284	12	20	activation	activation	NOUN
easat-284	12	21	.	.	PUNCT
easat-284	13	1	in	in	ADP
easat-284	13	2	this	this	DET
easat-284	13	3	paper	paper	NOUN
easat-284	13	4	it	it	PRON
easat-284	13	5	’s	’s	AUX
easat-284	13	6	hypothesized	hypothesize	VERB
easat-284	13	7	that	that	SCONJ
easat-284	13	8	the	the	DET
easat-284	13	9	severity	severity	NOUN
easat-284	13	10	of	of	ADP
easat-284	13	11	covid-19	covid-19	PROPN
easat-284	13	12	is	be	AUX
easat-284	13	13	induced	induce	VERB
easat-284	13	14	by	by	ADP
easat-284	13	15	recruitment	recruitment	NOUN
easat-284	13	16	of	of	ADP
easat-284	13	17	innate	innate	ADJ
easat-284	13	18	responder	responder	NOUN
easat-284	13	19	neutrophils	neutrophil	NOUN
easat-284	13	20	,	,	PUNCT
easat-284	13	21	which	which	PRON
easat-284	13	22	release	release	VERB
easat-284	13	23	proteases	protease	NOUN
easat-284	13	24	and	and	CCONJ
easat-284	13	25	nets	net	NOUN
easat-284	13	26	inducing	induce	VERB
easat-284	13	27	endothelial	endothelial	ADJ
easat-284	13	28	damage	damage	NOUN
easat-284	13	29	and	and	CCONJ
easat-284	13	30	imbalance	imbalance	NOUN
easat-284	13	31	of	of	ADP
easat-284	13	32	the	the	DET
easat-284	13	33	four	four	NUM
easat-284	13	34	major	major	ADJ
easat-284	13	35	proteolytic	proteolytic	ADJ
easat-284	13	36	cascades	cascade	NOUN
easat-284	13	37	(	(	PUNCT
easat-284	13	38	coagulation	coagulation	NOUN
easat-284	13	39	,	,	PUNCT
easat-284	13	40	complement	complement	NOUN
easat-284	13	41	,	,	PUNCT
easat-284	13	42	fibrinolysis	fibrinolysis	NOUN
easat-284	13	43	and	and	CCONJ
easat-284	13	44	kallikrein	kallikrein	VERB
easat-284	13	45	)	)	PUNCT
easat-284	13	46	with	with	ADP
easat-284	13	47	prevalence	prevalence	NOUN
easat-284	13	48	of	of	ADP
easat-284	13	49	activators	activator	NOUN
easat-284	13	50	over	over	ADP
easat-284	13	51	inhibitors	inhibitor	NOUN
easat-284	13	52	and	and	CCONJ
easat-284	13	53	consequent	consequent	ADJ
easat-284	13	54	thrombotic	thrombotic	ADJ
easat-284	13	55	complications	complication	NOUN
easat-284	13	56	.	.	PUNCT
easat-284	14	1	platelets	platelet	VERB
easat-284	14	2	adhesion	adhesion	NOUN
easat-284	14	3	to	to	ADP
easat-284	14	4	damaged	damage	VERB
easat-284	14	5	endothelium	endothelium	NOUN
easat-284	14	6	and	and	CCONJ
easat-284	14	7	vwfviii	vwfviii	ADJ
easat-284	14	8	multimers	multimer	NOUN
easat-284	14	9	presence	presence	NOUN
easat-284	14	10	,	,	PUNCT
easat-284	14	11	due	due	ADP
easat-284	14	12	to	to	ADP
easat-284	14	13	loss	loss	NOUN
easat-284	14	14	of	of	ADP
easat-284	14	15	adamts13	adamts13	NOUN
easat-284	14	16	,	,	PUNCT
easat-284	14	17	contributes	contribute	VERB
easat-284	14	18	to	to	ADP
easat-284	14	19	hypercoagulability	hypercoagulability	NOUN
easat-284	14	20	state	state	NOUN
easat-284	14	21	.	.	PUNCT
easat-284	15	1	human	human	ADJ
easat-284	15	2	plasma	plasma	NOUN
easat-284	15	3	or	or	CCONJ
easat-284	15	4	serine	serine	NOUN
easat-284	15	5	protease	protease	NOUN
easat-284	15	6	inhibitors	inhibitor	NOUN
easat-284	15	7	like	like	ADP
easat-284	15	8	aprotinin	aprotinin	NOUN
easat-284	15	9	can	can	AUX
easat-284	15	10	help	help	VERB
easat-284	15	11	to	to	PART
easat-284	15	12	control	control	VERB
easat-284	15	13	neutrophil	neutrophil	ADJ
easat-284	15	14	induced	induce	VERB
easat-284	15	15	“	"	PUNCT
easat-284	15	16	proteolytic	proteolytic	ADJ
easat-284	15	17	storm	storm	NOUN
easat-284	15	18	”	"	PUNCT
easat-284	15	19	.	.	PUNCT
easat-284	16	1	the	the	DET
easat-284	16	2	goal	goal	NOUN
easat-284	16	3	of	of	ADP
easat-284	16	4	this	this	DET
easat-284	16	5	paper	paper	NOUN
easat-284	16	6	is	be	AUX
easat-284	16	7	to	to	PART
easat-284	16	8	support	support	VERB
easat-284	16	9	the	the	DET
easat-284	16	10	view	view	NOUN
easat-284	16	11	that	that	SCONJ
easat-284	16	12	,	,	PUNCT
easat-284	16	13	in	in	ADP
easat-284	16	14	sars	sar	NOUN
easat-284	16	15	-	-	PUNCT
easat-284	16	16	cov-2	cov-2	PART
easat-284	16	17	infection	infection	NOUN
easat-284	16	18	,	,	PUNCT
easat-284	16	19	proteases	protease	NOUN
easat-284	16	20	have	have	AUX
easat-284	16	21	a	a	DET
easat-284	16	22	key	key	ADJ
easat-284	16	23	role	role	NOUN
easat-284	16	24	and	and	CCONJ
easat-284	16	25	exceeding	exceed	VERB
easat-284	16	26	imbalanced	imbalanced	ADJ
easat-284	16	27	neutrophil	neutrophil	ADJ
easat-284	16	28	innate	innate	ADJ
easat-284	16	29	“	"	PUNCT
easat-284	16	30	unfriendly	unfriendly	ADJ
easat-284	16	31	fire	fire	NOUN
easat-284	16	32	”	"	PUNCT
easat-284	16	33	response	response	NOUN
easat-284	16	34	can	can	AUX
easat-284	16	35	be	be	AUX
easat-284	16	36	identified	identify	VERB
easat-284	16	37	as	as	ADP
easat-284	16	38	the	the	DET
easat-284	16	39	trigger	trigger	NOUN
easat-284	16	40	of	of	ADP
easat-284	16	41	a	a	DET
easat-284	16	42	“	"	PUNCT
easat-284	16	43	proteolytic	proteolytic	ADJ
easat-284	16	44	storm	storm	NOUN
easat-284	16	45	”	"	PUNCT
easat-284	16	46	,	,	PUNCT
easat-284	16	47	responsible	responsible	ADJ
easat-284	16	48	for	for	ADP
easat-284	16	49	subsequent	subsequent	ADJ
easat-284	16	50	well	well	ADV
easat-284	16	51	known	know	VERB
easat-284	16	52	hyper	hyper	ADJ
easat-284	16	53	coagulation	coagulation	NOUN
easat-284	16	54	and	and	CCONJ
easat-284	16	55	“	"	PUNCT
easat-284	16	56	cytokine	cytokine	ADJ
easat-284	16	57	storm	storm	NOUN
easat-284	16	58	”	"	PUNCT
easat-284	16	59	and	and	CCONJ
easat-284	16	60	human	human	ADJ
easat-284	16	61	plasma	plasma	NOUN
easat-284	16	62	,	,	PUNCT
easat-284	16	63	in	in	ADP
easat-284	16	64	adequate	adequate	ADJ
easat-284	16	65	volumes	volume	NOUN
easat-284	16	66	,	,	PUNCT
easat-284	16	67	together	together	ADV
easat-284	16	68	with	with	ADP
easat-284	16	69	serine	serine	NOUN
easat-284	16	70	proteases	protease	NOUN
easat-284	16	71	inhibitors	inhibitor	NOUN
easat-284	16	72	can	can	AUX
easat-284	16	73	be	be	AUX
easat-284	16	74	an	an	DET
easat-284	16	75	effective	effective	ADJ
easat-284	16	76	therapeutic	therapeutic	ADJ
easat-284	16	77	strategy	strategy	NOUN
easat-284	16	78	.	.	PUNCT
easat-284	17	1	keywords	keyword	NOUN
easat-284	17	2	:	:	PUNCT
easat-284	17	3	neutrophilia	neutrophilia	PROPN
easat-284	17	4	,	,	PUNCT
easat-284	17	5	covid-19	covid-19	PROPN
easat-284	17	6	,	,	PUNCT
easat-284	17	7	proteolytic	proteolytic	ADJ
easat-284	17	8	storm	storm	NOUN
easat-284	17	9	,	,	PUNCT
easat-284	17	10	sars	sar	NOUN
easat-284	17	11	-	-	PUNCT
easat-284	17	12	cov-2	cov-2	PART
easat-284	17	13	infection	infection	NOUN
easat-284	17	14	.	.	PUNCT
easat-284	18	1	abbreviations	abbreviation	NOUN
easat-284	18	2	:	:	PUNCT
easat-284	18	3	prrs	prr	NOUN
easat-284	18	4	-	-	PUNCT
easat-284	18	5	pattern	pattern	NOUN
easat-284	18	6	recognition	recognition	NOUN
easat-284	18	7	receptors	receptor	NOUN
easat-284	18	8	,	,	PUNCT
easat-284	18	9	irfs	irfs	PROPN
easat-284	18	10	-	-	PUNCT
easat-284	18	11	interferon	interferon	ADJ
easat-284	18	12	regulatory	regulatory	ADJ
easat-284	18	13	factors	factor	NOUN
easat-284	18	14	,	,	PUNCT
easat-284	18	15	itih4	itih4	NOUN
easat-284	18	16	-	-	PUNCT
easat-284	18	17	inter	inter	ADJ
easat-284	18	18	-	-	ADJ
easat-284	18	19	α	α	PRON
easat-284	18	20	-	-	PUNCT
easat-284	18	21	trypsin	trypsin	NOUN
easat-284	18	22	inhibitor	inhibitor	NOUN
easat-284	18	23	heavy	heavy	ADJ
easat-284	18	24	chain	chain	NOUN
easat-284	18	25	4	4	NUM
easat-284	18	26	,	,	PUNCT
easat-284	18	27	hphaptoglobin	hphaptoglobin	NOUN
easat-284	18	28	,	,	PUNCT
easat-284	18	29	lrg1	lrg1	NOUN
easat-284	18	30	-	-	PUNCT
easat-284	18	31	leucine	leucine	NOUN
easat-284	18	32	-	-	PUNCT
easat-284	18	33	rich	rich	ADJ
easat-284	18	34	alpha-2	alpha-2	NOUN
easat-284	18	35	-	-	PUNCT
easat-284	18	36	glycoprotein	glycoprotein	NOUN
easat-284	18	37	,	,	PUNCT
easat-284	18	38	lbp	lbp	NOUN
easat-284	18	39	-	-	PUNCT
easat-284	18	40	liposaccharide	liposaccharide	NOUN
easat-284	18	41	binding	bind	VERB
easat-284	18	42	protein	protein	NOUN
easat-284	18	43	,	,	PUNCT
easat-284	18	44	pars	par	NOUN
easat-284	18	45	-	-	PUNCT
easat-284	18	46	protease	protease	NOUN
easat-284	18	47	-	-	PUNCT
easat-284	18	48	activated	activate	VERB
easat-284	18	49	receptors	receptor	NOUN
easat-284	18	50	,	,	PUNCT
easat-284	18	51	nlr	nlr	PROPN
easat-284	18	52	-	-	PUNCT
easat-284	18	53	neutro	neutro	PROPN
easat-284	18	54	phil	phil	NOUN
easat-284	18	55	to	to	ADP
easat-284	18	56	-	-	PUNCT
easat-284	18	57	lymphocyte	lymphocyte	ADJ
easat-284	18	58	ratio	ratio	NOUN
easat-284	18	59	,	,	PUNCT
easat-284	18	60	nets	net	NOUN
easat-284	18	61	-	-	PUNCT
easat-284	18	62	neutrophil	neutrophil	ADJ
easat-284	18	63	extracellular	extracellular	ADJ
easat-284	18	64	traps	trap	NOUN
easat-284	18	65	,	,	PUNCT
easat-284	18	66	cp	cp	NOUN
easat-284	18	67	-	-	ADJ
easat-284	18	68	convalescent	convalescent	NOUN
easat-284	18	69	plasma	plasma	NOUN
easat-284	18	70	,	,	PUNCT
easat-284	18	71	sars	sar	NOUN
easat-284	18	72	-	-	PUNCT
easat-284	18	73	severe	severe	ADJ
easat-284	18	74	acute	acute	ADJ
easat-284	18	75	respiratory	respiratory	ADJ
easat-284	18	76	syndrome	syndrome	NOUN
easat-284	18	77	,	,	PUNCT
easat-284	18	78	s1	s1	NOUN
easat-284	18	79	-	-	PUNCT
easat-284	18	80	rbd	rbd	NOUN
easat-284	18	81	-	-	PUNCT
easat-284	18	82	spike1receptor	spike1receptor	NOUN
easat-284	18	83	binding	bind	VERB
easat-284	18	84	protein	protein	NOUN
easat-284	18	85	,	,	PUNCT
easat-284	18	86	saes	sae	NOUN
easat-284	18	87	-	-	PUNCT
easat-284	18	88	severe	severe	ADJ
easat-284	18	89	adverse	adverse	ADJ
easat-284	18	90	events	event	NOUN
easat-284	18	91	,	,	PUNCT
easat-284	18	92	daf	daf	ADJ
easat-284	18	93	-	-	PUNCT
easat-284	18	94	decay	decay	NOUN
easat-284	18	95	-	-	PUNCT
easat-284	18	96	accelerating	accelerate	VERB
easat-284	18	97	factor	factor	NOUN
easat-284	18	98	.	.	PUNCT
easat-284	19	1	1	1	X
easat-284	19	2	.	.	X
easat-284	19	3	introduction	introduction	NOUN
easat-284	19	4	according	accord	VERB
easat-284	19	5	to	to	ADP
easat-284	19	6	the	the	DET
easat-284	19	7	largest	large	ADJ
easat-284	19	8	current	current	ADJ
easat-284	19	9	report	report	NOUN
easat-284	19	10	from	from	ADP
easat-284	19	11	the	the	DET
easat-284	19	12	chinese	chinese	ADJ
easat-284	19	13	center	center	NOUN
easat-284	19	14	for	for	ADP
easat-284	19	15	disease	disease	NOUN
easat-284	19	16	control	control	NOUN
easat-284	19	17	and	and	CCONJ
easat-284	19	18	prevention	prevention	NOUN
easat-284	19	19	with	with	ADP
easat-284	19	20	72	72	NUM
easat-284	19	21	314	314	NUM
easat-284	19	22	cases	case	NOUN
easat-284	19	23	,	,	PUNCT
easat-284	19	24	58	58	NUM
easat-284	19	25	574	574	NUM
easat-284	19	26	patients	patient	NOUN
easat-284	19	27	(	(	PUNCT
easat-284	19	28	81	81	NUM
easat-284	19	29	%	%	NOUN
easat-284	19	30	)	)	PUNCT
easat-284	19	31	were	be	AUX
easat-284	19	32	classified	classify	VERB
easat-284	19	33	as	as	ADP
easat-284	19	34	mild	mild	ADJ
easat-284	19	35	,	,	PUNCT
easat-284	19	36	10	10	NUM
easat-284	19	37	124	124	NUM
easat-284	19	38	(	(	PUNCT
easat-284	19	39	14	14	NUM
easat-284	19	40	%	%	NOUN
easat-284	19	41	)	)	PUNCT
easat-284	19	42	were	be	AUX
easat-284	19	43	classified	classify	VERB
easat-284	19	44	as	as	ADP
easat-284	19	45	severe	severe	ADJ
easat-284	19	46	,	,	PUNCT
easat-284	19	47	and	and	CCONJ
easat-284	19	48	3616	3616	NUM
easat-284	19	49	(	(	PUNCT
easat-284	19	50	5	5	NUM
easat-284	19	51	%	%	NOUN
easat-284	19	52	)	)	PUNCT
easat-284	19	53	were	be	AUX
easat-284	19	54	considered	consider	VERB
easat-284	19	55	critical	critical	ADJ
easat-284	19	56	(	(	PUNCT
easat-284	19	57	respiratory	respiratory	ADJ
easat-284	19	58	failure	failure	NOUN
easat-284	19	59	,	,	PUNCT
easat-284	19	60	septic	septic	ADJ
easat-284	19	61	shock	shock	NOUN
easat-284	19	62	,	,	PUNCT
easat-284	19	63	and/or	and/or	CCONJ
easat-284	19	64	multiple	multiple	ADJ
easat-284	19	65	organ	organ	NOUN
easat-284	19	66	failure	failure	NOUN
easat-284	19	67	)	)	PUNCT
easat-284	20	1	[	[	X
easat-284	20	2	1	1	NUM
easat-284	20	3	]	]	PUNCT
easat-284	20	4	.	.	PUNCT
easat-284	21	1	among	among	ADP
easat-284	21	2	201	201	NUM
easat-284	21	3	patients	patient	NOUN
easat-284	21	4	in	in	ADP
easat-284	21	5	wuhan	wuhan	PROPN
easat-284	21	6	,	,	PUNCT
easat-284	21	7	wu	wu	PROPN
easat-284	21	8	,	,	PUNCT
easat-284	21	9	et	et	PROPN
easat-284	21	10	al	al	PROPN
easat-284	21	11	.	.	PUNCT
easat-284	22	1	[	[	X
easat-284	22	2	2	2	X
easat-284	22	3	]	]	PUNCT
easat-284	22	4	reported	report	VERB
easat-284	22	5	that	that	SCONJ
easat-284	22	6	risk	risk	NOUN
easat-284	22	7	factors	factor	NOUN
easat-284	22	8	associated	associate	VERB
easat-284	22	9	with	with	ADP
easat-284	22	10	development	development	NOUN
easat-284	22	11	of	of	ADP
easat-284	22	12	acute	acute	ADJ
easat-284	22	13	respiratory	respiratory	ADJ
easat-284	22	14	distress	distress	NOUN
easat-284	22	15	syndrome	syndrome	NOUN
easat-284	22	16	and	and	CCONJ
easat-284	22	17	death	death	NOUN
easat-284	22	18	included	include	VERB
easat-284	22	19	older	old	ADJ
easat-284	22	20	age	age	NOUN
easat-284	22	21	,	,	PUNCT
easat-284	22	22	neutrophilia	neutrophilia	PROPN
easat-284	22	23	,	,	PUNCT
easat-284	22	24	organ	organ	NOUN
easat-284	22	25	dysfunction	dysfunction	NOUN
easat-284	22	26	,	,	PUNCT
easat-284	22	27	coagulopathy	coagulopathy	ADJ
easat-284	22	28	and	and	CCONJ
easat-284	22	29	elevated	elevated	ADJ
easat-284	22	30	d	d	ADJ
easat-284	22	31	-	-	PUNCT
easat-284	22	32	dimer	dimer	ADJ
easat-284	22	33	levels	level	NOUN
easat-284	22	34	.	.	PUNCT
easat-284	23	1	as	as	ADP
easat-284	23	2	of	of	ADP
easat-284	23	3	november	november	PROPN
easat-284	23	4	24	24	NUM
easat-284	23	5	,	,	PUNCT
easat-284	23	6	2020	2020	NUM
easat-284	23	7	,	,	PUNCT
easat-284	23	8	john	john	PROPN
easat-284	23	9	hopkins	hopkins	PROPN
easat-284	23	10	covid-19	covid-19	PROPN
easat-284	23	11	dashboard	dashboard	NOUN
easat-284	23	12	has	have	AUX
easat-284	23	13	documented	document	VERB
easat-284	23	14	a	a	DET
easat-284	23	15	total	total	NOUN
easat-284	23	16	of	of	ADP
easat-284	23	17	59.400.000	59.400.000	NUM
easat-284	23	18	cases	case	NOUN
easat-284	23	19	with	with	ADP
easat-284	23	20	over	over	ADP
easat-284	23	21	1.400.000	1.400.000	NUM
easat-284	23	22	deaths	death	NOUN
easat-284	23	23	worldwide	worldwide	ADV
easat-284	23	24	.	.	PUNCT
easat-284	24	1	the	the	DET
easat-284	24	2	sars	sar	NOUN
easat-284	24	3	-	-	PUNCT
easat-284	24	4	cov-2	cov-2	PART
easat-284	24	5	infection	infection	NOUN
easat-284	24	6	is	be	AUX
easat-284	24	7	a	a	DET
easat-284	24	8	protease	protease	NOUN
easat-284	24	9	dependent	dependent	ADJ
easat-284	24	10	process	process	NOUN
easat-284	24	11	as	as	ADP
easat-284	24	12	cell	cell	NOUN
easat-284	24	13	entry	entry	NOUN
easat-284	24	14	depends	depend	VERB
easat-284	24	15	on	on	ADP
easat-284	24	16	the	the	DET
easat-284	24	17	binding	binding	NOUN
easat-284	24	18	of	of	ADP
easat-284	24	19	the	the	DET
easat-284	24	20	spike	spike	ADJ
easat-284	24	21	protein	protein	NOUN
easat-284	24	22	’s	’s	PART
easat-284	24	23	s1	s1	NOUN
easat-284	24	24	subunit	subunit	NOUN
easat-284	24	25	to	to	PART
easat-284	24	26	ace2	ace2	VERB
easat-284	24	27	on	on	ADP
easat-284	24	28	the	the	DET
easat-284	24	29	target	target	NOUN
easat-284	24	30	cell	cell	NOUN
easat-284	24	31	surface	surface	NOUN
easat-284	24	32	and	and	CCONJ
easat-284	24	33	host	host	NOUN
easat-284	24	34	proteases	protease	NOUN
easat-284	24	35	,	,	PUNCT
easat-284	24	36	furin	furin	NOUN
easat-284	24	37	,	,	PUNCT
easat-284	24	38	as	as	ADP
easat-284	24	39	wel	wel	PROPN
easat-284	24	40	l	l	PROPN
easat-284	24	41	as	as	SCONJ
easat-284	24	42	tmprss2	tmprss2	PRON
easat-284	24	43	processes	process	VERB
easat-284	24	44	the	the	DET
easat-284	24	45	s	s	NOUN
easat-284	24	46	protein	protein	NOUN
easat-284	24	47	to	to	PART
easat-284	24	48	facilitate	facilitate	VERB
easat-284	24	49	membrane	membrane	NOUN
easat-284	24	50	fusion	fusion	NOUN
easat-284	24	51	,	,	PUNCT
easat-284	24	52	allowing	allow	VERB
easat-284	24	53	sars	sar	NOUN
easat-284	24	54	-	-	PUNCT
easat-284	24	55	cov-2	cov-2	NOUN
easat-284	24	56	to	to	PART
easat-284	24	57	have	have	AUX
easat-284	24	58	enhanced	enhance	VERB
easat-284	24	59	proteolytic	proteolytic	ADJ
easat-284	24	60	activation	activation	NOUN
easat-284	24	61	in	in	ADP
easat-284	24	62	a	a	DET
easat-284	24	63	wider	wide	ADJ
easat-284	24	64	range	range	NOUN
easat-284	24	65	of	of	ADP
easat-284	24	66	tissues	tissue	NOUN
easat-284	24	67	[	[	X
easat-284	24	68	3	3	NUM
easat-284	24	69	]	]	PUNCT
easat-284	24	70	.	.	PUNCT
easat-284	25	1	the	the	DET
easat-284	25	2	strategy	strategy	NOUN
easat-284	25	3	used	use	VERB
easat-284	25	4	by	by	ADP
easat-284	25	5	sars	sar	NOUN
easat-284	25	6	-	-	PUNCT
easat-284	25	7	cov-2	cov-2	NOUN
easat-284	25	8	for	for	ADP
easat-284	25	9	cellular	cellular	ADJ
easat-284	25	10	entry	entry	NOUN
easat-284	25	11	is	be	AUX
easat-284	25	12	the	the	DET
easat-284	25	13	same	same	ADJ
easat-284	25	14	in	in	ADP
easat-284	25	15	all	all	DET
easat-284	25	16	the	the	DET
easat-284	25	17	tissues	tissue	NOUN
easat-284	25	18	presenting	present	VERB
easat-284	25	19	dual	dual	ADJ
easat-284	25	20	-	-	PUNCT
easat-284	25	21	positive	positive	ADJ
easat-284	25	22	ace2+tmprss2+cells	ace2+tmprss2+cell	NOUN
easat-284	25	23	,	,	PUNCT
easat-284	25	24	employing	employ	VERB
easat-284	25	25	its	its	PRON
easat-284	25	26	s	s	NOUN
easat-284	25	27	protein	protein	NOUN
easat-284	25	28	,	,	PUNCT
easat-284	25	29	previously	previously	ADV
easat-284	25	30	primed	prime	VERB
easat-284	25	31	by	by	ADP
easat-284	25	32	tmprss2	tmprss2	ADP
easat-284	25	33	protease	protease	NOUN
easat-284	25	34	and	and	CCONJ
easat-284	25	35	ca	can	AUX
easat-284	25	36	thepsin	thepsin	PROPN
easat-284	25	37	b	b	PROPN
easat-284	25	38	/	/	SYM
easat-284	25	39	l	l	NOUN
easat-284	25	40	,	,	PUNCT
easat-284	25	41	binding	bind	VERB
easat-284	25	42	to	to	ADP
easat-284	25	43	ace2	ace2	NOUN
easat-284	25	44	receptor	receptor	NOUN
easat-284	25	45	[	[	X
easat-284	25	46	4	4	NUM
easat-284	25	47	-	-	SYM
easat-284	25	48	8	8	NUM
easat-284	25	49	]	]	PUNCT
easat-284	25	50	.	.	PUNCT
easat-284	26	1	ace2	ace2	PROPN
easat-284	26	2	,	,	PUNCT
easat-284	26	3	the	the	DET
easat-284	26	4	viral	viral	ADJ
easat-284	26	5	receptor	receptor	NOUN
easat-284	26	6	,	,	PUNCT
easat-284	26	7	and	and	CCONJ
easat-284	26	8	one	one	NUM
easat-284	26	9	of	of	ADP
easat-284	26	10	its	its	PRON
easat-284	26	11	entry	entry	NOUN
easat-284	26	12	-	-	PUNCT
easat-284	26	13	associated	associate	VERB
easat-284	26	14	proteases	protease	NOUN
easat-284	26	15	,	,	PUNCT
easat-284	26	16	tmprss2	tmprss2	ADV
easat-284	26	17	,	,	PUNCT
easat-284	26	18	are	be	AUX
easat-284	26	19	expressed	express	VERB
easat-284	26	20	in	in	ADP
easat-284	26	21	nasal	nasal	PROPN
easat-284	26	22	goblet	goblet	NOUN
easat-284	26	23	cells	cell	NOUN
easat-284	26	24	,	,	PUNCT
easat-284	26	25	in	in	ADP
easat-284	26	26	lung	lung	NOUN
easat-284	26	27	goblet	goblet	NOUN
easat-284	26	28	,	,	PUNCT
easat-284	26	29	multiciliated	multiciliated	ADJ
easat-284	26	30	and	and	CCONJ
easat-284	26	31	at2	at2	NOUN
easat-284	26	32	cells	cell	NOUN
easat-284	26	33	and	and	CCONJ
easat-284	26	34	gut	gut	VERB
easat-284	26	35	epithelial	epithelial	ADJ
easat-284	26	36	enterocytes	enterocyte	NOUN
easat-284	26	37	,	,	PUNCT
easat-284	26	38	in	in	ADP
easat-284	26	39	pancreatic	pancreatic	ADJ
easat-284	26	40	ductal	ductal	ADJ
easat-284	26	41	cells	cell	NOUN
easat-284	26	42	,	,	PUNCT
easat-284	26	43	bladder	bladder	NOUN
easat-284	26	44	,	,	PUNCT
easat-284	26	45	testis	testis	NOUN
easat-284	26	46	,	,	PUNCT
easat-284	26	47	prostate	prostate	NOUN
easat-284	26	48	and	and	CCONJ
easat-284	26	49	kidney	kidney	NOUN
easat-284	26	50	epithelial	epithelial	ADJ
easat-284	26	51	cells	cell	NOUN
easat-284	26	52	,	,	PUNCT
easat-284	26	53	cholangiocytes	cholangiocyte	NOUN
easat-284	26	54	,	,	PUNCT
easat-284	26	55	oligodendrocytes	oligodendrocyte	NOUN
easat-284	26	56	in	in	ADP
easat-284	26	57	the	the	DET
easat-284	26	58	brain	brain	NOUN
easat-284	26	59	,	,	PUNCT
easat-284	26	60	inhibitory	inhibitory	ADJ
easat-284	26	61	enteric	enteric	ADJ
easat-284	26	62	neurons	neuron	NOUN
easat-284	26	63	,	,	PUNCT
easat-284	26	64	heart	heart	NOUN
easat-284	26	65	fibroblasts	fibroblast	NOUN
easat-284	26	66	/	/	SYM
easat-284	26	67	pericytes	pericyte	NOUN
easat-284	26	68	,	,	PUNCT
easat-284	26	69	and	and	CCONJ
easat-284	26	70	fibroblasts	fibroblast	NOUN
easat-284	26	71	and	and	CCONJ
easat-284	26	72	pericytes	pericyte	NOUN
easat-284	26	73	in	in	ADP
easat-284	26	74	multiple	multiple	ADJ
easat-284	26	75	other	other	ADJ
easat-284	26	76	tissues	tissue	NOUN
easat-284	26	77	(	(	PUNCT
easat-284	26	78	figure1	figure1	X
easat-284	26	79	)	)	PUNCT
easat-284	26	80	.	.	PUNCT
easat-284	27	1	in	in	ADP
easat-284	27	2	line	line	NOUN
easat-284	27	3	with	with	ADP
easat-284	27	4	the	the	DET
easat-284	27	5	kidney	kidney	NOUN
easat-284	27	6	’s	’s	PART
easat-284	27	7	role	role	NOUN
easat-284	27	8	in	in	ADP
easat-284	27	9	the	the	DET
easat-284	27	10	renin	renin	ADJ
easat-284	27	11	-	-	PUNCT
easat-284	27	12	angiotensin	angiotensin	NOUN
easat-284	27	13	-	-	PUNCT
easat-284	27	14	aldosterone	aldosterone	NOUN
easat-284	27	15	system	system	NOUN
easat-284	27	16	,	,	PUNCT
easat-284	27	17	dualpositive	dualpositive	ADJ
easat-284	27	18	cells	cell	NOUN
easat-284	27	19	are	be	AUX
easat-284	27	20	enriched	enrich	VERB
easat-284	27	21	in	in	ADP
easat-284	27	22	the	the	DET
easat-284	27	23	proximal	proximal	ADJ
easat-284	27	24	tubular	tubular	ADJ
easat-284	27	25	cells	cell	NOUN
easat-284	27	26	and	and	CCONJ
easat-284	27	27	in	in	ADP
easat-284	27	28	principal	principal	ADJ
easat-284	27	29	cells	cell	NOUN
easat-284	27	30	of	of	ADP
easat-284	27	31	the	the	DET
easat-284	27	32	collecting	collect	VERB
easat-284	27	33	duct	duct	NOUN
easat-284	27	34	[	[	X
easat-284	27	35	9	9	NUM
easat-284	27	36	]	]	PUNCT
easat-284	27	37	.	.	PUNCT
easat-284	28	1	a	a	DET
easat-284	28	2	recent	recent	ADJ
easat-284	28	3	paper	paper	NOUN
easat-284	28	4	has	have	AUX
easat-284	28	5	shown	show	VERB
easat-284	28	6	that	that	SCONJ
easat-284	28	7	therapeutic	therapeutic	ADJ
easat-284	28	8	aprotinin	aprotinin	NOUN
easat-284	28	9	concentrations	concentration	NOUN
easat-284	28	10	inhibit	inhibit	VERB
easat-284	28	11	sars	sar	NOUN
easat-284	28	12	-	-	PUNCT
easat-284	28	13	cov-2	cov-2	NOUN
easat-284	28	14	replication	replication	NOUN
easat-284	28	15	as	as	ADP
easat-284	28	16	entry	entry	NOUN
easat-284	28	17	inhibitors	inhibitor	NOUN
easat-284	28	18	and	and	CCONJ
easat-284	28	19	by	by	ADP
easat-284	28	20	compensating	compensate	VERB
easat-284	28	21	for	for	ADP
easat-284	28	22	down	down	ADP
easat-284	28	23	regulated	regulated	ADJ
easat-284	28	24	cellular	cellular	ADJ
easat-284	28	25	protease	protease	NOUN
easat-284	28	26	inhibitors	inhibitor	NOUN
easat-284	28	27	during	during	ADP
easat-284	28	28	later	later	ADJ
easat-284	28	29	replication	replication	NOUN
easat-284	28	30	cycles	cycle	NOUN
easat-284	28	31	[	[	X
easat-284	28	32	10	10	NUM
easat-284	28	33	]	]	PUNCT
easat-284	28	34	.	.	PUNCT
easat-284	29	1	aprotinin	aprotinin	PROPN
easat-284	29	2	aerosol	aerosol	NOUN
easat-284	29	3	,	,	PUNCT
easat-284	29	4	as	as	SCONJ
easat-284	29	5	approved	approve	VERB
easat-284	29	6	in	in	ADP
easat-284	29	7	russia	russia	PROPN
easat-284	29	8	for	for	ADP
easat-284	29	9	the	the	DET
easat-284	29	10	treatment	treatment	NOUN
easat-284	29	11	of	of	ADP
easat-284	29	12	influenza	influenza	NOUN
easat-284	29	13	,	,	PUNCT
easat-284	29	14	may	may	AUX
easat-284	29	15	be	be	AUX
easat-284	29	16	a	a	DET
easat-284	29	17	particularly	particularly	ADV
easat-284	29	18	promising	promising	ADJ
easat-284	29	19	strategy	strategy	NOUN
easat-284	29	20	to	to	PART
easat-284	29	21	suppress	suppress	VERB
easat-284	29	22	virus	virus	NOUN
easat-284	29	23	replication	replication	NOUN
easat-284	29	24	and	and	CCONJ
easat-284	29	25	thus	thus	ADV
easat-284	29	26	prevent	prevent	VERB
easat-284	29	27	covid-19	covid-19	PROPN
easat-284	29	28	lung	lung	NOUN
easat-284	29	29	injury	injury	NOUN
easat-284	29	30	[	[	X
easat-284	29	31	11	11	NUM
easat-284	29	32	]	]	PUNCT
easat-284	29	33	.	.	PUNCT
easat-284	30	1	figure	figure	NOUN
easat-284	30	2	1	1	NUM
easat-284	30	3	.	.	PUNCT
easat-284	31	1	human	human	ADJ
easat-284	31	2	cell	cell	NOUN
easat-284	31	3	types	type	NOUN
easat-284	31	4	potential	potential	ADJ
easat-284	31	5	sars	sar	NOUN
easat-284	31	6	-	-	PUNCT
easat-284	31	7	cov-2	cov-2	NOUN
easat-284	31	8	targets	target	NOUN
easat-284	31	9	due	due	ADJ
easat-284	31	10	to	to	ADP
easat-284	31	11	dual	dual	ADJ
easat-284	31	12	expression	expression	NOUN
easat-284	31	13	of	of	ADP
easat-284	31	14	ace2	ace2	NOUN
easat-284	31	15	receptor	receptor	NOUN
easat-284	31	16	and	and	CCONJ
easat-284	31	17	tmprss2	tmprss2	PROPN
easat-284	31	18	.	.	PROPN
easat-284	32	1	68	68	NUM
easat-284	32	2	edelweiss	edelweiss	PROPN
easat-284	32	3	applied	apply	VERB
easat-284	32	4	science	science	NOUN
easat-284	32	5	and	and	CCONJ
easat-284	32	6	technology	technology	NOUN
easat-284	32	7	issn	issn	PROPN
easat-284	32	8	:	:	PUNCT
easat-284	32	9	2576	2576	NUM
easat-284	32	10	-	-	SYM
easat-284	32	11	8484	8484	NUM
easat-284	32	12	vol	vol	NOUN
easat-284	32	13	.	.	PROPN
easat-284	33	1	4	4	NUM
easat-284	33	2	,	,	PUNCT
easat-284	33	3	no	no	INTJ
easat-284	33	4	.	.	NOUN
easat-284	33	5	1	1	NUM
easat-284	33	6	:	:	SYM
easat-284	33	7	67	67	NUM
easat-284	33	8	-	-	SYM
easat-284	33	9	73	73	NUM
easat-284	33	10	,	,	PUNCT
easat-284	33	11	2020	2020	NUM
easat-284	33	12	doi	doi	NOUN
easat-284	33	13	:	:	PUNCT
easat-284	33	14	10.33805/2576	10.33805/2576	NUM
easat-284	33	15	-	-	SYM
easat-284	33	16	8484.184	8484.184	NUM
easat-284	33	17	©	©	PROPN
easat-284	33	18	2020	2020	NUM
easat-284	33	19	by	by	ADP
easat-284	33	20	the	the	DET
easat-284	33	21	author	author	NOUN
easat-284	33	22	1.1	1.1	NUM
easat-284	33	23	.	.	PUNCT
easat-284	34	1	severe	severe	ADJ
easat-284	34	2	covid-19	covid-19	PROPN
easat-284	34	3	:	:	PUNCT
easat-284	34	4	profound	profound	ADJ
easat-284	34	5	immunologic	immunologic	ADJ
easat-284	34	6	imbalance	imbalance	NOUN
easat-284	34	7	inverse	inverse	NOUN
easat-284	34	8	correlation	correlation	NOUN
easat-284	34	9	between	between	ADP
easat-284	34	10	disease	disease	NOUN
easat-284	34	11	severity	severity	NOUN
easat-284	34	12	and	and	CCONJ
easat-284	34	13	lymphopenia	lymphopenia	NOUN
easat-284	34	14	has	have	AUX
easat-284	34	15	been	be	AUX
easat-284	34	16	observed	observe	VERB
easat-284	34	17	according	accord	VERB
easat-284	34	18	to	to	ADP
easat-284	34	19	tan	tan	PROPN
easat-284	34	20	,	,	PUNCT
easat-284	34	21	et	et	PROPN
easat-284	34	22	al	al	PROPN
easat-284	34	23	.	.	PUNCT
easat-284	35	1	[	[	X
easat-284	35	2	12	12	NUM
easat-284	35	3	]	]	X
easat-284	35	4	critical	critical	ADJ
easat-284	35	5	patients	patient	NOUN
easat-284	35	6	with	with	ADP
easat-284	35	7	lymphocyte	lymphocyte	ADJ
easat-284	35	8	percentage	percentage	NOUN
easat-284	35	9	<	<	NOUN
easat-284	35	10	5	5	NUM
easat-284	35	11	%	%	NOUN
easat-284	35	12	were	be	AUX
easat-284	35	13	more	more	ADV
easat-284	35	14	likely	likely	ADJ
easat-284	35	15	to	to	PART
easat-284	35	16	become	become	VERB
easat-284	35	17	critically	critically	ADV
easat-284	35	18	ill	ill	ADJ
easat-284	35	19	,	,	PUNCT
easat-284	35	20	with	with	ADP
easat-284	35	21	need	need	NOUN
easat-284	35	22	for	for	ADP
easat-284	35	23	intensive	intensive	ADJ
easat-284	35	24	care	care	NOUN
easat-284	35	25	therapy	therapy	NOUN
easat-284	35	26	and	and	CCONJ
easat-284	35	27	high	high	ADJ
easat-284	35	28	mortality	mortality	NOUN
easat-284	35	29	rate	rate	NOUN
easat-284	35	30	.	.	PUNCT
easat-284	36	1	along	along	ADP
easat-284	36	2	the	the	DET
easat-284	36	3	same	same	ADJ
easat-284	36	4	line	line	NOUN
easat-284	36	5	,	,	PUNCT
easat-284	36	6	imbalance	imbalance	NOUN
easat-284	36	7	between	between	ADP
easat-284	36	8	interferon	interferon	ADJ
easat-284	36	9	production	production	NOUN
easat-284	36	10	and	and	CCONJ
easat-284	36	11	chemokines	chemokine	NOUN
easat-284	36	12	and	and	CCONJ
easat-284	36	13	an	an	DET
easat-284	36	14	“	"	PUNCT
easat-284	36	15	eicosanoid	eicosanoid	ADJ
easat-284	36	16	storm	storm	NOUN
easat-284	36	17	”	"	PUNCT
easat-284	36	18	have	have	AUX
easat-284	36	19	been	be	AUX
easat-284	36	20	found	find	VERB
easat-284	36	21	.	.	PUNCT
easat-284	37	1	the	the	DET
easat-284	37	2	physiological	physiological	ADJ
easat-284	37	3	response	response	NOUN
easat-284	37	4	to	to	ADP
easat-284	37	5	virus	virus	NOUN
easat-284	37	6	infection	infection	NOUN
easat-284	37	7	starts	start	VERB
easat-284	37	8	at	at	ADP
easat-284	37	9	intracellular	intracellular	ADJ
easat-284	37	10	replication	replication	NOUN
easat-284	37	11	,	,	PUNCT
easat-284	37	12	through	through	ADP
easat-284	37	13	pattern	pattern	NOUN
easat-284	37	14	recognition	recognition	NOUN
easat-284	37	15	receptors	receptor	NOUN
easat-284	37	16	(	(	PUNCT
easat-284	37	17	prrs	prr	NOUN
easat-284	37	18	)	)	PUNCT
easat-284	37	19	and	and	CCONJ
easat-284	37	20	transcription	transcription	NOUN
easat-284	37	21	factors	factor	NOUN
easat-284	37	22	(	(	PUNCT
easat-284	37	23	interferon	interferon	ADJ
easat-284	37	24	regulatory	regulatory	ADJ
easat-284	37	25	factors	factor	NOUN
easat-284	37	26	(	(	PUNCT
easat-284	37	27	irfs	irfs	PROPN
easat-284	37	28	)	)	PUNCT
easat-284	37	29	and	and	CCONJ
easat-284	37	30	nuclear	nuclear	ADJ
easat-284	37	31	factor	factor	NOUN
easat-284	37	32	kb	kb	PROPN
easat-284	37	33	)	)	PUNCT
easat-284	37	34	activation	activation	NOUN
easat-284	37	35	,	,	PUNCT
easat-284	37	36	inducing	induce	VERB
easat-284	37	37	cellular	cellular	ADJ
easat-284	37	38	antiviral	antiviral	NOUN
easat-284	37	39	de	de	X
easat-284	37	40	fenses	fense	NOUN
easat-284	37	41	(	(	PUNCT
easat-284	37	42	ifni	ifni	NOUN
easat-284	37	43	and	and	CCONJ
easat-284	37	44	ifn	ifn	PROPN
easat-284	37	45	-	-	PUNCT
easat-284	37	46	iii	iii	NOUN
easat-284	37	47	,	,	PUNCT
easat-284	37	48	respectively	respectively	ADV
easat-284	37	49	)	)	PUNCT
easat-284	37	50	and	and	CCONJ
easat-284	37	51	subsequent	subsequent	ADJ
easat-284	37	52	up	up	ADP
easat-284	37	53	regulation	regulation	NOUN
easat-284	37	54	of	of	ADP
easat-284	37	55	isgs	isg	NOUN
easat-284	37	56	and	and	CCONJ
easat-284	37	57	leukocytes	leukocyte	NOUN
easat-284	37	58	recruitment	recruitment	NOUN
easat-284	37	59	by	by	ADP
easat-284	37	60	chemokine	chemokine	ADJ
easat-284	37	61	secretion	secretion	NOUN
easat-284	37	62	[	[	X
easat-284	37	63	13	13	NUM
easat-284	37	64	-	-	SYM
easat-284	37	65	15	15	NUM
easat-284	37	66	]	]	PUNCT
easat-284	37	67	.	.	PUNCT
easat-284	38	1	imbalance	imbalance	NOUN
easat-284	38	2	between	between	ADP
easat-284	38	3	interferon	interferon	NOUN
easat-284	38	4	and	and	CCONJ
easat-284	38	5	chemokines	chemokine	NOUN
easat-284	38	6	:	:	PUNCT
easat-284	38	7	early	early	ADJ
easat-284	38	8	interferon	interferon	ADJ
easat-284	38	9	antiviral	antiviral	ADJ
easat-284	38	10	activity	activity	NOUN
easat-284	38	11	is	be	AUX
easat-284	38	12	depressed	depressed	ADJ
easat-284	38	13	,	,	PUNCT
easat-284	38	14	while	while	SCONJ
easat-284	38	15	innate	innate	ADJ
easat-284	38	16	immunity	immunity	NOUN
easat-284	38	17	neutrophils	neutrophil	NOUN
easat-284	38	18	are	be	AUX
easat-284	38	19	highly	highly	ADV
easat-284	38	20	recruited	recruit	VERB
easat-284	38	21	.	.	PUNCT
easat-284	39	1	the	the	DET
easat-284	39	2	infected	infected	ADJ
easat-284	39	3	cells	cell	NOUN
easat-284	39	4	delay	delay	VERB
easat-284	39	5	the	the	DET
easat-284	39	6	ifn	ifn	PROPN
easat-284	39	7	-	-	PUNCT
easat-284	39	8	i	i	PRON
easat-284	39	9	and	and	CCONJ
easat-284	39	10	-iii	-iii	VERB
easat-284	39	11	response	response	NOUN
easat-284	39	12	by	by	ADP
easat-284	39	13	inhibiting	inhibit	VERB
easat-284	39	14	innate	innate	ADJ
easat-284	39	15	immune	immune	ADJ
easat-284	39	16	signaling	signal	VERB
easat-284	39	17	,	,	PUNCT
easat-284	39	18	induce	induce	VERB
easat-284	39	19	up	up	ADP
easat-284	39	20	regulation	regulation	NOUN
easat-284	39	21	of	of	ADP
easat-284	39	22	chemo	chemo	NOUN
easat-284	39	23	attractants	attractant	NOUN
easat-284	39	24	for	for	ADP
easat-284	39	25	neutrophils	neutrophil	NOUN
easat-284	39	26	and	and	CCONJ
easat-284	39	27	monocytes	monocyte	NOUN
easat-284	39	28	(	(	PUNCT
easat-284	39	29	hmgb1	hmgb1	PROPN
easat-284	39	30	,	,	PUNCT
easat-284	39	31	ccl2	ccl2	PROPN
easat-284	39	32	,	,	PUNCT
easat-284	39	33	ccl8	ccl8	NOUN
easat-284	39	34	and	and	CCONJ
easat-284	39	35	cxcl	cxcl	PROPN
easat-284	39	36	family	family	NOUN
easat-284	39	37	)	)	PUNCT
easat-284	39	38	cytokines	cytokine	VERB
easat-284	39	39	storm	storm	NOUN
easat-284	39	40	(	(	PUNCT
easat-284	39	41	il-2r	il-2r	NOUN
easat-284	39	42	,	,	PUNCT
easat-284	39	43	il1ra	il1ra	NOUN
easat-284	39	44	,	,	PUNCT
easat-284	39	45	il-6	il-6	PRON
easat-284	39	46	,	,	PUNCT
easat-284	39	47	il-8	il-8	NOUN
easat-284	39	48	,	,	PUNCT
easat-284	39	49	il-10	il-10	PRON
easat-284	39	50	and	and	CCONJ
easat-284	39	51	tnf	tnf	PROPN
easat-284	39	52	)	)	PUNCT
easat-284	39	53	and	and	CCONJ
easat-284	40	1	increased	increase	VERB
easat-284	40	2	reactants	reactant	NOUN
easat-284	40	3	biomarkers	biomarker	NOUN
easat-284	40	4	(	(	PUNCT
easat-284	40	5	example	example	NOUN
easat-284	40	6	:	:	PUNCT
easat-284	40	7	procalcitonin	procalcitonin	ADJ
easat-284	40	8	,	,	PUNCT
easat-284	40	9	serum	serum	NOUN
easat-284	40	10	ferritin	ferritin	ADJ
easat-284	40	11	,	,	PUNCT
easat-284	40	12	and	and	CCONJ
easat-284	40	13	c	c	NOUN
easat-284	40	14	-	-	PUNCT
easat-284	40	15	reactive	reactive	ADJ
easat-284	40	16	protein	protein	NOUN
easat-284	40	17	)	)	PUNCT
easat-284	41	1	[	[	X
easat-284	41	2	16	16	NUM
easat-284	41	3	]	]	PUNCT
easat-284	41	4	.	.	PUNCT
easat-284	42	1	the	the	DET
easat-284	42	2	combination	combination	NOUN
easat-284	42	3	of	of	ADP
easat-284	42	4	tnf	tnf	PROPN
easat-284	42	5	-	-	PUNCT
easat-284	42	6	α	α	PROPN
easat-284	42	7	and	and	CCONJ
easat-284	42	8	ifn	ifn	PROPN
easat-284	42	9	-	-	PUNCT
easat-284	42	10	γ	γ	NOUN
easat-284	42	11	induced	induce	VERB
easat-284	42	12	inflammatory	inflammatory	ADJ
easat-284	42	13	cell	cell	NOUN
easat-284	42	14	death	death	NOUN
easat-284	42	15	characterized	characterize	VERB
easat-284	42	16	by	by	ADP
easat-284	42	17	pyroptosis	pyroptosis	NOUN
easat-284	42	18	,	,	PUNCT
easat-284	42	19	apoptosis	apoptosis	NOUN
easat-284	42	20	,	,	PUNCT
easat-284	42	21	and	and	CCONJ
easat-284	42	22	necroptosis	necroptosis	NOUN
easat-284	42	23	(	(	PUNCT
easat-284	42	24	panoptosis	panoptosis	NOUN
easat-284	42	25	)	)	PUNCT
easat-284	42	26	.	.	PUNCT
easat-284	43	1	mechanistically	mechanistically	ADV
easat-284	43	2	,	,	PUNCT
easat-284	43	3	tnf	tnf	PROPN
easat-284	43	4	-	-	PUNCT
easat-284	43	5	α	α	PROPN
easat-284	43	6	and	and	CCONJ
easat-284	43	7	ifn	ifn	PROPN
easat-284	43	8	-	-	PUNCT
easat-284	43	9	γ	γ	NOUN
easat-284	43	10	co	co	NOUN
easat-284	43	11	-	-	NOUN
easat-284	43	12	treatment	treatment	NOUN
easat-284	43	13	activated	activate	VERB
easat-284	43	14	the	the	DET
easat-284	43	15	jak	jak	PROPN
easat-284	43	16	/	/	SYM
easat-284	43	17	stat1	stat1	PROPN
easat-284	43	18	/	/	SYM
easat-284	43	19	irf1	irf1	PROPN
easat-284	43	20	axis	axis	NOUN
easat-284	43	21	,	,	PUNCT
easat-284	43	22	inducing	induce	VERB
easat-284	43	23	nitric	nitric	ADJ
easat-284	43	24	oxide	oxide	NOUN
easat-284	43	25	production	production	NOUN
easat-284	43	26	and	and	CCONJ
easat-284	43	27	driving	drive	VERB
easat-284	43	28	caspase8	caspase8	PROPN
easat-284	43	29	/	/	SYM
easat-284	43	30	fadd	fadd	NOUN
easat-284	43	31	-	-	PUNCT
easat-284	43	32	mediated	mediate	VERB
easat-284	43	33	panoptosis	panoptosis	NOUN
easat-284	43	34	.	.	PUNCT
easat-284	44	1	tnf	tnf	PROPN
easat-284	44	2	-	-	PUNCT
easat-284	44	3	α	α	PROPN
easat-284	44	4	and	and	CCONJ
easat-284	44	5	ifn	ifn	PROPN
easat-284	44	6	-	-	PUNCT
easat-284	44	7	γ	γ	NOUN
easat-284	44	8	caused	cause	VERB
easat-284	44	9	a	a	DET
easat-284	44	10	lethal	lethal	ADJ
easat-284	44	11	cytokine	cytokine	NOUN
easat-284	44	12	shock	shock	NOUN
easat-284	44	13	in	in	ADP
easat-284	44	14	mice	mouse	NOUN
easat-284	44	15	that	that	PRON
easat-284	44	16	mirrors	mirror	VERB
easat-284	44	17	the	the	DET
easat-284	44	18	tissue	tissue	NOUN
easat-284	44	19	damage	damage	NOUN
easat-284	44	20	and	and	CCONJ
easat-284	44	21	inflammation	inflammation	NOUN
easat-284	44	22	of	of	ADP
easat-284	44	23	covid-19	covid-19	PROPN
easat-284	44	24	and	and	CCONJ
easat-284	44	25	inhibiting	inhibit	VERB
easat-284	44	26	panoptosis	panoptosis	NOUN
easat-284	44	27	protected	protect	VERB
easat-284	44	28	mice	mouse	NOUN
easat-284	44	29	from	from	ADP
easat-284	44	30	this	this	DET
easat-284	44	31	pathology	pathology	NOUN
easat-284	44	32	and	and	CCONJ
easat-284	44	33	death	death	NOUN
easat-284	45	1	[	[	X
easat-284	45	2	17	17	NUM
easat-284	45	3	]	]	PUNCT
easat-284	45	4	.	.	PUNCT
easat-284	46	1	proteomic	proteomic	NOUN
easat-284	46	2	and	and	CCONJ
easat-284	46	3	metabolomic	metabolomic	ADJ
easat-284	46	4	studies	study	NOUN
easat-284	46	5	showed	show	VERB
easat-284	46	6	activation	activation	NOUN
easat-284	46	7	of	of	ADP
easat-284	46	8	complement	complement	NOUN
easat-284	46	9	pathways	pathway	NOUN
easat-284	46	10	,	,	PUNCT
easat-284	46	11	acute	acute	NOUN
easat-284	46	12	phase	phase	NOUN
easat-284	46	13	reactants	reactant	VERB
easat-284	46	14	(	(	PUNCT
easat-284	46	15	c	c	NOUN
easat-284	46	16	-	-	ADJ
easat-284	46	17	reactive	reactive	ADJ
easat-284	46	18	protein	protein	NOUN
easat-284	46	19	and	and	CCONJ
easat-284	46	20	serum	serum	VERB
easat-284	46	21	amyloid	amyloid	NOUN
easat-284	46	22	proteins	protein	NOUN
easat-284	46	23	saa1	saa1	NOUN
easat-284	46	24	and	and	CCONJ
easat-284	46	25	saa2	saa2	ADJ
easat-284	46	26	)	)	PUNCT
easat-284	46	27	,	,	PUNCT
easat-284	46	28	proteins	protein	NOUN
easat-284	46	29	implicated	implicate	VERB
easat-284	46	30	in	in	ADP
easat-284	46	31	interleukin	interleukin	NOUN
easat-284	46	32	il-6	il-6	NOUN
easat-284	46	33	signaling	signal	VERB
easat-284	46	34	,	,	PUNCT
easat-284	46	35	inter	inter	ADJ
easat-284	46	36	-	-	ADJ
easat-284	46	37	α	α	PRON
easat-284	46	38	-	-	PUNCT
easat-284	46	39	trypsin	trypsin	NOUN
easat-284	46	40	inhibitor	inhibitor	NOUN
easat-284	46	41	heavy	heavy	ADJ
easat-284	46	42	chain	chain	NOUN
easat-284	46	43	4	4	NUM
easat-284	46	44	(	(	PUNCT
easat-284	46	45	itih4	itih4	PROPN
easat-284	46	46	)	)	PUNCT
easat-284	46	47	,	,	PUNCT
easat-284	46	48	haptoglobin	haptoglobin	NOUN
easat-284	46	49	(	(	PUNCT
easat-284	46	50	hp	hp	PROPN
easat-284	46	51	)	)	PUNCT
easat-284	46	52	,	,	PUNCT
easat-284	46	53	leucine	leucine	NOUN
easat-284	46	54	-	-	PUNCT
easat-284	46	55	rich	rich	ADJ
easat-284	46	56	alpha-2	alpha-2	NOUN
easat-284	46	57	-	-	PUNCT
easat-284	46	58	glycoprotein	glycoprotein	NOUN
easat-284	46	59	(	(	PUNCT
easat-284	46	60	lrg1	lrg1	PROPN
easat-284	46	61	)	)	PUNCT
easat-284	46	62	,	,	PUNCT
easat-284	46	63	monocyte	monocyte	NOUN
easat-284	46	64	differentiation	differentiation	NOUN
easat-284	46	65	antigen	antigen	ADP
easat-284	46	66	cd14	cd14	PROPN
easat-284	46	67	and	and	CCONJ
easat-284	46	68	the	the	DET
easat-284	46	69	liposaccharide	liposaccharide	NOUN
easat-284	46	70	binding	bind	VERB
easat-284	46	71	protein	protein	NOUN
easat-284	46	72	(	(	PUNCT
easat-284	46	73	lbp	lbp	PROPN
easat-284	46	74	)	)	PUNCT
easat-284	46	75	,	,	PUNCT
easat-284	46	76	known	know	VERB
easat-284	46	77	to	to	PART
easat-284	46	78	induce	induce	VERB
easat-284	46	79	il-6	il-6	NOUN
easat-284	46	80	expression	expression	NOUN
easat-284	46	81	.	.	PUNCT
easat-284	47	1	thus	thus	ADV
easat-284	47	2	,	,	PUNCT
easat-284	47	3	the	the	DET
easat-284	47	4	proteomic	proteomic	ADJ
easat-284	47	5	approach	approach	NOUN
easat-284	47	6	surprisingly	surprisingly	ADV
easat-284	47	7	revealed	reveal	VERB
easat-284	47	8	a	a	DET
easat-284	47	9	very	very	ADV
easat-284	47	10	il-6	il-6	NOUN
easat-284	47	11	centered	center	VERB
easat-284	47	12	response	response	NOUN
easat-284	47	13	.	.	PUNCT
easat-284	48	1	sars	sar	NOUN
easat-284	48	2	-	-	PUNCT
easat-284	48	3	cov-2	cov-2	PART
easat-284	48	4	infected	infected	ADJ
easat-284	48	5	lung	lung	NOUN
easat-284	48	6	cells	cell	NOUN
easat-284	48	7	also	also	ADV
easat-284	48	8	overexpressed	overexpresse	VERB
easat-284	48	9	complement	complement	NOUN
easat-284	48	10	activation	activation	NOUN
easat-284	48	11	genes	gene	NOUN
easat-284	48	12	,	,	PUNCT
easat-284	48	13	involved	involve	VERB
easat-284	48	14	in	in	ADP
easat-284	48	15	neutrophil	neutrophil	ADJ
easat-284	48	16	degranulation	degranulation	NOUN
easat-284	48	17	,	,	PUNCT
easat-284	48	18	with	with	ADP
easat-284	48	19	deposits	deposit	NOUN
easat-284	48	20	of	of	ADP
easat-284	48	21	terminal	terminal	ADJ
easat-284	48	22	complement	complement	NOUN
easat-284	48	23	components	component	NOUN
easat-284	48	24	c5b	c5b	PROPN
easat-284	48	25	-9	-9	PROPN
easat-284	48	26	,	,	PUNCT
easat-284	48	27	c4d	c4d	PROPN
easat-284	48	28	and	and	CCONJ
easat-284	48	29	masp2	masp2	NOUN
easat-284	48	30	attacking	attack	VERB
easat-284	48	31	the	the	DET
easat-284	48	32	host	host	NOUN
easat-284	48	33	ecs	ec	NOUN
easat-284	48	34	and	and	CCONJ
easat-284	48	35	causing	cause	VERB
easat-284	48	36	transmembrane	transmembrane	ADJ
easat-284	48	37	channel	channel	NOUN
easat-284	48	38	formation	formation	NOUN
easat-284	48	39	on	on	ADP
easat-284	48	40	the	the	DET
easat-284	48	41	endothelium	endothelium	NOUN
easat-284	48	42	and	and	CCONJ
easat-284	48	43	inducing	inducing	ADJ
easat-284	48	44	endotheliopathy	endotheliopathy	ADJ
easat-284	48	45	,	,	PUNCT
easat-284	48	46	involved	involve	VERB
easat-284	48	47	in	in	ADP
easat-284	48	48	ards	ard	NOUN
easat-284	48	49	like	like	ADP
easat-284	48	50	syndrome	syndrome	NOUN
easat-284	48	51	with	with	ADP
easat-284	48	52	systemic	systemic	ADJ
easat-284	48	53	inflammation	inflammation	NOUN
easat-284	48	54	and	and	CCONJ
easat-284	48	55	lung	lung	NOUN
easat-284	48	56	neutrophilia	neutrophilia	PROPN
easat-284	49	1	[	[	X
easat-284	49	2	18	18	NUM
easat-284	49	3	]	]	PUNCT
easat-284	49	4	.	.	PUNCT
easat-284	50	1	an	an	DET
easat-284	50	2	up	up	ADJ
easat-284	50	3	regulation	regulation	NOUN
easat-284	50	4	of	of	ADP
easat-284	50	5	fibrinogen	fibrinogen	NOUN
easat-284	50	6	,	,	PUNCT
easat-284	50	7	protein	protein	NOUN
easat-284	50	8	z	z	NOUN
easat-284	50	9	-	-	PUNCT
easat-284	50	10	dependent	dependent	ADJ
easat-284	50	11	protease	protease	NOUN
easat-284	50	12	inhibitor	inhibitor	NOUN
easat-284	50	13	and	and	CCONJ
easat-284	50	14	serpina10	serpina10	NOUN
easat-284	50	15	was	be	AUX
easat-284	50	16	found	find	VERB
easat-284	50	17	,	,	PUNCT
easat-284	50	18	further	far	ADV
easat-284	50	19	highlighting	highlight	VERB
easat-284	50	20	the	the	DET
easat-284	50	21	importance	importance	NOUN
easat-284	50	22	of	of	ADP
easat-284	50	23	coagulation	coagulation	NOUN
easat-284	50	24	in	in	ADP
easat-284	50	25	sars	sar	NOUN
easat-284	50	26	-	-	PUNCT
easat-284	50	27	cov-2	cov-2	PART
easat-284	50	28	infection	infection	NOUN
easat-284	50	29	.	.	PUNCT
easat-284	51	1	in	in	ADP
easat-284	51	2	severe	severe	ADJ
easat-284	51	3	covid-19	covid-19	PROPN
easat-284	51	4	lung	lung	NOUN
easat-284	51	5	infection	infection	NOUN
easat-284	51	6	,	,	PUNCT
easat-284	51	7	a	a	DET
easat-284	51	8	catastrophic	catastrophic	ADJ
easat-284	51	9	microvascular	microvascular	NOUN
easat-284	51	10	injury	injury	NOUN
easat-284	51	11	syndrome	syndrome	NOUN
easat-284	51	12	is	be	AUX
easat-284	51	13	caused	cause	VERB
easat-284	51	14	by	by	ADP
easat-284	51	15	activation	activation	NOUN
easat-284	51	16	of	of	ADP
easat-284	51	17	complement	complement	NOUN
easat-284	51	18	and	and	CCONJ
easat-284	51	19	coagulation	coagulation	NOUN
easat-284	51	20	pathways	pathway	NOUN
easat-284	51	21	,	,	PUNCT
easat-284	51	22	inducing	induce	VERB
easat-284	51	23	an	an	DET
easat-284	51	24	associ	associ	PROPN
easat-284	51	25	ated	ate	VERB
easat-284	51	26	procoagulant	procoagulant	NOUN
easat-284	51	27	state	state	NOUN
easat-284	52	1	[	[	X
easat-284	52	2	18	18	NUM
easat-284	52	3	]	]	PUNCT
easat-284	52	4	.	.	PUNCT
easat-284	53	1	imbalance	imbalance	NOUN
easat-284	53	2	between	between	ADP
easat-284	53	3	innate	innate	ADJ
easat-284	53	4	immunity	immunity	NOUN
easat-284	53	5	cells	cell	NOUN
easat-284	53	6	:	:	PUNCT
easat-284	53	7	qin	qin	PROPN
easat-284	53	8	,	,	PUNCT
easat-284	53	9	et	et	PROPN
easat-284	53	10	al	al	PROPN
easat-284	53	11	.	.	PUNCT
easat-284	54	1	[	[	X
easat-284	54	2	19	19	NUM
easat-284	54	3	]	]	PUNCT
easat-284	54	4	described	describe	VERB
easat-284	54	5	the	the	DET
easat-284	54	6	occurrence	occurrence	NOUN
easat-284	54	7	of	of	ADP
easat-284	54	8	a	a	DET
easat-284	54	9	dysregulated	dysregulated	ADJ
easat-284	54	10	immune	immune	ADJ
easat-284	54	11	response	response	NOUN
easat-284	54	12	with	with	ADP
easat-284	54	13	a	a	DET
easat-284	54	14	marked	mark	VERB
easat-284	54	15	decrease	decrease	NOUN
easat-284	54	16	in	in	ADP
easat-284	54	17	t	t	NOUN
easat-284	54	18	-	-	PUNCT
easat-284	54	19	cell	cell	NOUN
easat-284	54	20	number	number	NOUN
easat-284	54	21	,	,	PUNCT
easat-284	54	22	higher	high	ADJ
easat-284	54	23	leukocyte	leukocyte	NOUN
easat-284	54	24	counts	count	NOUN
easat-284	54	25	and	and	CCONJ
easat-284	54	26	neutrophil	neutrophil	NOUN
easat-284	54	27	-	-	PUNCT
easat-284	54	28	to	to	ADP
easat-284	54	29	-	-	PUNCT
easat-284	54	30	lymphocyte	lymphocyte	NOUN
easat-284	54	31	ratio	ratio	NOUN
easat-284	54	32	(	(	PUNCT
easat-284	54	33	nlr	nlr	PROPN
easat-284	54	34	)	)	PUNCT
easat-284	54	35	,	,	PUNCT
easat-284	54	36	as	as	ADV
easat-284	54	37	well	well	ADV
easat-284	54	38	as	as	ADP
easat-284	54	39	lower	low	ADJ
easat-284	54	40	percentages	percentage	NOUN
easat-284	54	41	of	of	ADP
easat-284	54	42	monocytes	monocyte	NOUN
easat-284	54	43	,	,	PUNCT
easat-284	54	44	eosinophils	eosinophil	NOUN
easat-284	54	45	,	,	PUNCT
easat-284	54	46	and	and	CCONJ
easat-284	54	47	basophils	basophils	PROPN
easat-284	54	48	.	.	PUNCT
easat-284	55	1	sars	sar	NOUN
easat-284	55	2	-	-	PUNCT
easat-284	55	3	cov-2	cov-2	NOUN
easat-284	55	4	nsp9	nsp9	PROPN
easat-284	55	5	and	and	CCONJ
easat-284	55	6	nsp10	nsp10	PROPN
easat-284	55	7	directly	directly	ADV
easat-284	55	8	target	target	VERB
easat-284	55	9	nkrf	nkrf	ADJ
easat-284	55	10	to	to	PART
easat-284	55	11	facilitate	facilitate	VERB
easat-284	55	12	il-8	il-8	NOUN
easat-284	55	13	/	/	SYM
easat-284	55	14	il-6	il-6	NOUN
easat-284	55	15	production	production	NOUN
easat-284	55	16	and	and	CCONJ
easat-284	55	17	thus	thus	ADV
easat-284	55	18	the	the	DET
easat-284	55	19	response	response	NOUN
easat-284	55	20	is	be	AUX
easat-284	55	21	imbalanced	imbalanced	ADJ
easat-284	55	22	versus	versus	ADP
easat-284	55	23	activation	activation	NOUN
easat-284	55	24	of	of	ADP
easat-284	55	25	the	the	DET
easat-284	55	26	innate	innate	ADJ
easat-284	55	27	immune	immune	ADJ
easat-284	55	28	response	response	NOUN
easat-284	55	29	[	[	X
easat-284	55	30	16	16	NUM
easat-284	55	31	]	]	PUNCT
easat-284	55	32	.	.	PUNCT
easat-284	56	1	innate	innate	ADJ
easat-284	56	2	immune	immune	ADJ
easat-284	56	3	response	response	NOUN
easat-284	56	4	plays	play	VERB
easat-284	56	5	an	an	DET
easat-284	56	6	important	important	ADJ
easat-284	56	7	protective	protective	ADJ
easat-284	56	8	or	or	CCONJ
easat-284	56	9	destructive	destructive	ADJ
easat-284	56	10	role	role	NOUN
easat-284	56	11	,	,	PUNCT
easat-284	56	12	depending	depend	VERB
easat-284	56	13	on	on	ADP
easat-284	56	14	the	the	DET
easat-284	56	15	progression	progression	NOUN
easat-284	56	16	of	of	ADP
easat-284	56	17	the	the	DET
easat-284	56	18	disease	disease	NOUN
easat-284	56	19	.	.	PUNCT
easat-284	57	1	the	the	DET
easat-284	57	2	association	association	NOUN
easat-284	57	3	between	between	ADP
easat-284	57	4	human	human	ADJ
easat-284	57	5	serine	serine	NOUN
easat-284	57	6	proteases	protease	NOUN
easat-284	57	7	t	t	PROPN
easat-284	57	8	rypsin	rypsin	NOUN
easat-284	57	9	,	,	PUNCT
easat-284	57	10	thrombin	thrombin	NOUN
easat-284	57	11	,	,	PUNCT
easat-284	57	12	tryptase	tryptase	NOUN
easat-284	57	13	,	,	PUNCT
easat-284	57	14	and	and	CCONJ
easat-284	57	15	elastase	elastase	VERB
easat-284	57	16	with	with	ADP
easat-284	57	17	increased	increase	VERB
easat-284	57	18	expression	expression	NOUN
easat-284	57	19	of	of	ADP
easat-284	57	20	mcp-1	mcp-1	NOUN
easat-284	57	21	has	have	AUX
easat-284	57	22	been	be	AUX
easat-284	57	23	shown	show	VERB
easat-284	57	24	and	and	CCONJ
easat-284	57	25	the	the	DET
easat-284	57	26	inhibition	inhibition	NOUN
easat-284	57	27	of	of	ADP
easat-284	57	28	these	these	DET
easat-284	57	29	proteases	protease	NOUN
easat-284	57	30	resulted	result	VERB
easat-284	57	31	in	in	ADP
easat-284	57	32	the	the	DET
easat-284	57	33	inhibition	inhibition	NOUN
easat-284	57	34	of	of	ADP
easat-284	57	35	mcp-1	mcp-1	NOUN
easat-284	57	36	secretion	secretion	NOUN
easat-284	57	37	via	via	ADP
easat-284	57	38	inactivation	inactivation	NOUN
easat-284	57	39	of	of	ADP
easat-284	57	40	various	various	ADJ
easat-284	57	41	protease	protease	NOUN
easat-284	57	42	-	-	PUNCT
easat-284	57	43	activated	activate	VERB
easat-284	57	44	receptors	receptor	NOUN
easat-284	57	45	(	(	PUNCT
easat-284	57	46	pars	par	NOUN
easat-284	57	47	)	)	PUNCT
easat-284	58	1	[	[	X
easat-284	58	2	20	20	NUM
easat-284	58	3	]	]	PUNCT
easat-284	58	4	.	.	PUNCT
easat-284	59	1	furthermore	furthermore	ADV
easat-284	59	2	,	,	PUNCT
easat-284	59	3	neutrophils	neutrophil	NOUN
easat-284	59	4	respond	respond	VERB
easat-284	59	5	to	to	ADP
easat-284	59	6	viral	viral	ADJ
easat-284	59	7	infections	infection	NOUN
easat-284	59	8	by	by	ADP
easat-284	59	9	activation	activation	NOUN
easat-284	59	10	of	of	ADP
easat-284	59	11	neutrophil	neutrophil	ADJ
easat-284	59	12	elastase	elastase	NOUN
easat-284	59	13	,	,	PUNCT
easat-284	59	14	cathepsin	cathepsin	NOUN
easat-284	59	15	g	g	NOUN
easat-284	59	16	,	,	PUNCT
easat-284	59	17	and	and	CCONJ
easat-284	59	18	proteinase	proteinase	NOUN
easat-284	59	19	3	3	NUM
easat-284	59	20	,	,	PUNCT
easat-284	59	21	playing	play	VERB
easat-284	59	22	roles	role	NOUN
easat-284	59	23	both	both	CCONJ
easat-284	59	24	intracellularly	intracellularly	ADJ
easat-284	59	25	and	and	CCONJ
easat-284	59	26	extracellularly	extracellularly	ADV
easat-284	59	27	[	[	X
easat-284	59	28	21	21	NUM
easat-284	59	29	,	,	PUNCT
easat-284	59	30	22	22	NUM
easat-284	59	31	]	]	PUNCT
easat-284	59	32	.	.	PUNCT
easat-284	60	1	however	however	ADV
easat-284	60	2	,	,	PUNCT
easat-284	60	3	the	the	DET
easat-284	60	4	presence	presence	NOUN
easat-284	60	5	of	of	ADP
easat-284	60	6	a	a	DET
easat-284	60	7	high	high	ADJ
easat-284	60	8	number	number	NOUN
easat-284	60	9	of	of	ADP
easat-284	60	10	neutrophils	neutrophil	NOUN
easat-284	60	11	at	at	ADP
easat-284	60	12	the	the	DET
easat-284	60	13	inflammation	inflammation	NOUN
easat-284	60	14	site	site	NOUN
easat-284	60	15	could	could	AUX
easat-284	60	16	correspond	correspond	VERB
easat-284	60	17	to	to	ADP
easat-284	60	18	imbalanced	imbalanced	ADJ
easat-284	60	19	protease	protease	NOUN
easat-284	60	20	activity	activity	NOUN
easat-284	60	21	.	.	PUNCT
easat-284	61	1	this	this	DET
easat-284	61	2	further	further	ADJ
easat-284	61	3	leads	lead	VERB
easat-284	61	4	to	to	ADP
easat-284	61	5	various	various	ADJ
easat-284	61	6	inflammatory	inflammatory	ADJ
easat-284	61	7	disorders	disorder	NOUN
easat-284	61	8	,	,	PUNCT
easat-284	61	9	tissue	tissue	NOUN
easat-284	61	10	damage	damage	NOUN
easat-284	61	11	,	,	PUNCT
easat-284	61	12	lung	lung	NOUN
easat-284	61	13	dystrophy	dystrophy	NOUN
easat-284	61	14	,	,	PUNCT
easat-284	61	15	ards	ard	NOUN
easat-284	61	16	,	,	PUNCT
easat-284	61	17	and	and	CCONJ
easat-284	61	18	potentially	potentially	ADV
easat-284	61	19	death	death	NOUN
easat-284	62	1	[	[	X
easat-284	62	2	22	22	NUM
easat-284	62	3	]	]	PUNCT
easat-284	62	4	(	(	PUNCT
easat-284	62	5	figure	figure	NOUN
easat-284	62	6	2	2	NUM
easat-284	62	7	)	)	PUNCT
easat-284	62	8	.	.	PUNCT
easat-284	63	1	figure	figure	NOUN
easat-284	63	2	2	2	NUM
easat-284	63	3	.	.	PUNCT
easat-284	63	4	innate	innate	VERB
easat-284	63	5	immunity	immunity	NOUN
easat-284	63	6	cells	cell	NOUN
easat-284	63	7	imbalance	imbalance	NOUN
easat-284	63	8	(	(	PUNCT
easat-284	63	9	personally	personally	ADV
easat-284	63	10	modified	modify	VERB
easat-284	63	11	by	by	ADP
easat-284	63	12	antonioli	antonioli	NOUN
easat-284	63	13	,	,	PUNCT
easat-284	63	14	et	et	PROPN
easat-284	63	15	al	al	PROPN
easat-284	63	16	.	.	PUNCT
easat-284	64	1	[	[	X
easat-284	64	2	23	23	NUM
easat-284	64	3	]	]	PUNCT
easat-284	64	4	.	.	PUNCT
easat-284	65	1	several	several	ADJ
easat-284	65	2	cytokines	cytokine	NOUN
easat-284	65	3	,	,	PUNCT
easat-284	65	4	such	such	ADJ
easat-284	65	5	as	as	ADP
easat-284	65	6	il6	il6	NOUN
easat-284	65	7	and	and	CCONJ
easat-284	65	8	il-10	il-10	PRON
easat-284	65	9	,	,	PUNCT
easat-284	65	10	were	be	AUX
easat-284	65	11	shown	show	VERB
easat-284	65	12	to	to	PART
easat-284	65	13	upregulate	upregulate	VERB
easat-284	65	14	nkg2a	nkg2a	NUM
easat-284	65	15	expression	expression	NOUN
easat-284	65	16	and	and	CCONJ
easat-284	65	17	consequent	consequent	ADJ
easat-284	65	18	lymphocyte	lymphocyte	ADJ
easat-284	65	19	downregulation	downregulation	NOUN
easat-284	65	20	,	,	PUNCT
easat-284	65	21	while	while	SCONJ
easat-284	65	22	il-6	il-6	PRON
easat-284	65	23	and	and	CCONJ
easat-284	65	24	il-8	il-8	VERB
easat-284	65	25	impair	impair	VERB
easat-284	65	26	the	the	DET
easat-284	65	27	functions	function	NOUN
easat-284	65	28	of	of	ADP
easat-284	65	29	nk	nk	PROPN
easat-284	65	30	cells	cell	NOUN
easat-284	65	31	via	via	ADP
easat-284	65	32	stat3	stat3	NOUN
easat-284	65	33	-	-	PUNCT
easat-284	65	34	dependent	dependent	ADJ
easat-284	65	35	mechanisms	mechanism	NOUN
easat-284	65	36	.	.	PUNCT
easat-284	66	1	nkg2a	nkg2a	NOUN
easat-284	66	2	,	,	PUNCT
easat-284	66	3	thus	thus	ADV
easat-284	66	4	,	,	PUNCT
easat-284	66	5	is	be	AUX
easat-284	66	6	a	a	DET
easat-284	66	7	key	key	ADJ
easat-284	66	8	factor	factor	NOUN
easat-284	66	9	in	in	ADP
easat-284	66	10	the	the	DET
easat-284	66	11	altered	altered	ADJ
easat-284	66	12	balance	balance	NOUN
easat-284	66	13	between	between	ADP
easat-284	66	14	neutrophils	neutrophil	NOUN
easat-284	66	15	and	and	CCONJ
easat-284	66	16	lymphocytes	lymphocyte	VERB
easat-284	66	17	[	[	X
easat-284	66	18	23	23	NUM
easat-284	66	19	]	]	PUNCT
easat-284	66	20	(	(	PUNCT
easat-284	66	21	figure	figure	NOUN
easat-284	66	22	2	2	NUM
easat-284	66	23	)	)	PUNCT
easat-284	66	24	.	.	PUNCT
easat-284	67	1	high	high	ADJ
easat-284	67	2	levels	level	NOUN
easat-284	67	3	of	of	ADP
easat-284	67	4	il-6	il-6	NOUN
easat-284	67	5	,	,	PUNCT
easat-284	67	6	il-8	il-8	PUNCT
easat-284	67	7	and	and	CCONJ
easat-284	67	8	g	g	NOUN
easat-284	67	9	-	-	PUNCT
easat-284	67	10	csf	csf	ADJ
easat-284	67	11	enhance	enhance	NOUN
easat-284	67	12	neutrophil	neutrophil	ADJ
easat-284	67	13	recruitment	recruitment	NOUN
easat-284	67	14	and	and	CCONJ
easat-284	67	15	express	express	VERB
easat-284	67	16	an	an	DET
easat-284	67	17	inhibitory	inhibitory	ADJ
easat-284	67	18	action	action	NOUN
easat-284	67	19	on	on	ADP
easat-284	67	20	nk	nk	PROPN
easat-284	67	21	cells	cell	NOUN
easat-284	67	22	further	far	ADV
easat-284	67	23	reducing	reduce	VERB
easat-284	67	24	interferon	interferon	NOUN
easat-284	67	25	(	(	PUNCT
easat-284	67	26	ifn)-γ	ifn)-γ	NOUN
easat-284	67	27	production	production	NOUN
easat-284	67	28	[	[	X
easat-284	67	29	24	24	NUM
easat-284	67	30	-	-	SYM
easat-284	67	31	26	26	NUM
easat-284	67	32	]	]	PUNCT
easat-284	67	33	.	.	PUNCT
easat-284	68	1	recent	recent	ADJ
easat-284	68	2	studies	study	NOUN
easat-284	68	3	and	and	CCONJ
easat-284	68	4	autopsy	autopsy	ADJ
easat-284	68	5	results	result	NOUN
easat-284	68	6	have	have	AUX
easat-284	68	7	confirmed	confirm	VERB
easat-284	68	8	infection	infection	NOUN
easat-284	68	9	and	and	CCONJ
easat-284	68	10	destruction	destruction	NOUN
easat-284	68	11	of	of	ADP
easat-284	68	12	lymphocytes	lymphocyte	NOUN
easat-284	68	13	in	in	ADP
easat-284	68	14	the	the	DET
easat-284	68	15	spleen	spleen	NOUN
easat-284	68	16	,	,	PUNCT
easat-284	68	17	lymph	lymph	NOUN
easat-284	68	18	nodes	node	NOUN
easat-284	68	19	,	,	PUNCT
easat-284	68	20	and	and	CCONJ
easat-284	68	21	lymphoid	lymphoid	ADJ
easat-284	68	22	tissues	tissue	NOUN
easat-284	68	23	of	of	ADP
easat-284	68	24	t	t	NOUN
easat-284	68	25	he	he	PRON
easat-284	68	26	gut	gut	VERB
easat-284	68	27	[	[	X
easat-284	68	28	26	26	NUM
easat-284	68	29	,	,	PUNCT
easat-284	68	30	27	27	NUM
easat-284	68	31	]	]	PUNCT
easat-284	68	32	.	.	PUNCT
easat-284	69	1	in	in	ADP
easat-284	69	2	these	these	DET
easat-284	69	3	sites	site	NOUN
easat-284	69	4	lymphocytes	lymphocyte	NOUN
easat-284	69	5	were	be	AUX
easat-284	69	6	reduced	reduce	VERB
easat-284	69	7	markedly	markedly	ADV
easat-284	69	8	in	in	ADP
easat-284	69	9	germinal	germinal	ADJ
easat-284	69	10	centers	center	NOUN
easat-284	69	11	and	and	CCONJ
easat-284	69	12	in	in	ADP
easat-284	69	13	situ	situ	ADJ
easat-284	69	14	hybridization	hybridization	NOUN
easat-284	69	15	detected	detect	VERB
easat-284	69	16	sars	sars	PROPN
easat-284	69	17	viral	viral	ADJ
easat-284	69	18	positivity	positivity	NOUN
easat-284	69	19	in	in	ADP
easat-284	69	20	the	the	DET
easat-284	69	21	residual	residual	ADJ
easat-284	69	22	immune	immune	ADJ
easat-284	69	23	cells	cell	NOUN
easat-284	69	24	in	in	ADP
easat-284	69	25	the	the	DET
easat-284	69	26	spleen	spleen	NOUN
easat-284	69	27	and	and	CCONJ
easat-284	69	28	in	in	ADP
easat-284	69	29	circulation	circulation	NOUN
easat-284	69	30	.	.	PUNCT
easat-284	70	1	respiratory	respiratory	ADJ
easat-284	70	2	tract	tract	NOUN
easat-284	70	3	infection	infection	NOUN
easat-284	70	4	,	,	PUNCT
easat-284	70	5	neutrophilia	neutrophilia	ADV
easat-284	70	6	,	,	PUNCT
easat-284	70	7	proteolytic	proteolytic	ADJ
easat-284	70	8	cascades	cascade	NOUN
easat-284	70	9	and	and	CCONJ
easat-284	70	10	platelets	platelet	NOUN
easat-284	70	11	activation	activation	NOUN
easat-284	70	12	resulting	result	VERB
easat-284	70	13	in	in	ADP
easat-284	70	14	inflammatory	inflammatory	ADJ
easat-284	70	15	endotheliopathic	endotheliopathic	ADJ
easat-284	70	16	,	,	PUNCT
easat-284	70	17	microangiopathy	microangiopathy	ADJ
easat-284	70	18	:	:	PUNCT
easat-284	70	19	focusing	focus	VERB
easat-284	70	20	on	on	ADP
easat-284	70	21	the	the	DET
easat-284	70	22	areas	area	NOUN
easat-284	70	23	of	of	ADP
easat-284	70	24	the	the	DET
easat-284	70	25	respiratory	respiratory	ADJ
easat-284	70	26	tract	tract	NOUN
easat-284	70	27	involved	involve	VERB
easat-284	70	28	and	and	CCONJ
easat-284	70	29	based	base	VERB
easat-284	70	30	on	on	ADP
easat-284	70	31	the	the	DET
easat-284	70	32	cells	cell	NOUN
easat-284	70	33	that	that	PRON
easat-284	70	34	are	be	AUX
easat-284	70	35	likely	likely	ADV
easat-284	70	36	infected	infect	VERB
easat-284	70	37	,	,	PUNCT
easat-284	70	38	covid-19	covid-19	PROPN
easat-284	70	39	can	can	AUX
easat-284	70	40	be	be	AUX
easat-284	70	41	divided	divide	VERB
easat-284	70	42	into	into	ADP
easat-284	70	43	three	three	NUM
easat-284	70	44	phases	phase	NOUN
easat-284	70	45	that	that	PRON
easat-284	70	46	correspond	correspond	VERB
easat-284	70	47	to	to	ADP
easat-284	70	48	different	different	ADJ
easat-284	70	49	clinical	clinical	ADJ
easat-284	70	50	stages	stage	NOUN
easat-284	70	51	of	of	ADP
easat-284	70	52	the	the	DET
easat-284	70	53	disease	disease	NOUN
easat-284	70	54	.	.	PUNCT
easat-284	71	1	stage	stage	NOUN
easat-284	71	2	1	1	NUM
easat-284	71	3	:	:	PUNCT
easat-284	71	4	asymptomatic	asymptomatic	ADJ
easat-284	71	5	state	state	NOUN
easat-284	71	6	(	(	PUNCT
easat-284	71	7	initial	initial	ADJ
easat-284	71	8	1	1	NUM
easat-284	71	9	-	-	SYM
easat-284	71	10	2	2	NUM
easat-284	71	11	days	day	NOUN
easat-284	71	12	of	of	ADP
easat-284	71	13	infection	infection	NOUN
easat-284	71	14	):	):	PUNCT
easat-284	71	15	inhaled	inhale	VERB
easat-284	71	16	virus	virus	NOUN
easat-284	71	17	sars	sar	NOUN
easat-284	71	18	-	-	PUNCT
easat-284	71	19	cov-2	cov-2	PART
easat-284	71	20	likely	likely	ADV
easat-284	71	21	binds	bind	VERB
easat-284	71	22	to	to	ADP
easat-284	71	23	epithelial	epithelial	ADJ
easat-284	71	24	cells	cell	NOUN
easat-284	71	25	in	in	ADP
easat-284	71	26	the	the	DET
easat-284	71	27	nasal	nasal	ADJ
easat-284	71	28	cavity	cavity	NOUN
easat-284	71	29	and	and	CCONJ
easat-284	71	30	starts	start	VERB
easat-284	71	31	replicating	replicate	VERB
easat-284	71	32	.	.	PUNCT
easat-284	72	1	the	the	DET
easat-284	72	2	viral	viral	ADJ
easat-284	72	3	burden	burden	NOUN
easat-284	72	4	may	may	AUX
easat-284	72	5	be	be	AUX
easat-284	72	6	low	low	ADJ
easat-284	72	7	.	.	PUNCT
easat-284	73	1	stage	stage	NOUN
easat-284	73	2	2	2	NUM
easat-284	73	3	:	:	PUNCT
easat-284	73	4	upper	upper	ADJ
easat-284	73	5	airway	airway	NOUN
easat-284	73	6	and	and	CCONJ
easat-284	73	7	conducting	conduct	VERB
easat-284	73	8	airway	airway	NOUN
easat-284	73	9	response	response	NOUN
easat-284	73	10	(	(	PUNCT
easat-284	73	11	next	next	ADJ
easat-284	73	12	few	few	ADJ
easat-284	73	13	days	day	NOUN
easat-284	73	14	):	):	PUNCT
easat-284	73	15	virus	virus	NOUN
easat-284	73	16	propagates	propagate	VERB
easat-284	73	17	and	and	CCONJ
easat-284	73	18	migrates	migrate	VERB
easat-284	73	19	down	down	ADP
easat-284	73	20	the	the	DET
easat-284	73	21	re	re	X
easat-284	73	22	spiratory	spiratory	NOUN
easat-284	73	23	tract	tract	NOUN
easat-284	73	24	along	along	ADP
easat-284	73	25	the	the	DET
easat-284	73	26	conducting	conducting	NOUN
easat-284	73	27	airways	airway	NOUN
easat-284	73	28	.	.	PUNCT
easat-284	74	1	stage	stage	NOUN
easat-284	74	2	3	3	NUM
easat-284	74	3	:	:	PUNCT
easat-284	74	4	alveolar	alveolar	ADJ
easat-284	74	5	phase	phase	NOUN
easat-284	74	6	.	.	PUNCT
easat-284	75	1	the	the	DET
easat-284	75	2	disease	disease	NOUN
easat-284	75	3	covid-19	covid-19	PROPN
easat-284	75	4	is	be	AUX
easat-284	75	5	clinically	clinically	ADV
easat-284	75	6	manifest	manifest	ADJ
easat-284	75	7	.	.	PUNCT
easat-284	76	1	about	about	ADV
easat-284	76	2	19	19	NUM
easat-284	76	3	%	%	NOUN
easat-284	76	4	of	of	ADP
easat-284	76	5	the	the	DET
easat-284	76	6	infected	infected	ADJ
easat-284	76	7	patients	patient	NOUN
easat-284	76	8	will	will	AUX
easat-284	76	9	progress	progress	VERB
easat-284	76	10	to	to	PART
easat-284	76	11	stage	stage	VERB
easat-284	76	12	3	3	NUM
easat-284	76	13	diseases	disease	NOUN
easat-284	76	14	and	and	CCONJ
easat-284	76	15	will	will	AUX
easat-284	76	16	develop	develop	VERB
easat-284	76	17	pulmonary	pulmonary	ADJ
easat-284	76	18	infiltrates	infiltrate	NOUN
easat-284	76	19	.	.	PUNCT
easat-284	77	1	the	the	DET
easat-284	77	2	virus	virus	NOUN
easat-284	77	3	infects	infect	VERB
easat-284	77	4	alveolar	alveolar	ADJ
easat-284	77	5	type	type	NOUN
easat-284	77	6	ii	ii	NOUN
easat-284	77	7	cells	cell	NOUN
easat-284	77	8	.	.	PUNCT
easat-284	78	1	sarscov-2	sarscov-2	NUM
easat-284	78	2	propagates	propagate	VERB
easat-284	78	3	within	within	ADP
easat-284	78	4	type	type	NOUN
easat-284	78	5	ii	ii	NOUN
easat-284	78	6	cells	cell	NOUN
easat-284	78	7	,	,	PUNCT
easat-284	78	8	large	large	ADJ
easat-284	78	9	numbers	number	NOUN
easat-284	78	10	of	of	ADP
easat-284	78	11	viral	viral	ADJ
easat-284	78	12	particles	particle	NOUN
easat-284	78	13	are	be	AUX
easat-284	78	14	released	release	VERB
easat-284	78	15	and	and	CCONJ
easat-284	78	16	the	the	DET
easat-284	78	17	cells	cell	NOUN
easat-284	78	18	undergo	undergo	VERB
easat-284	78	19	apoptosis	apoptosis	NOUN
easat-284	78	20	and	and	CCONJ
easat-284	78	21	die	die	VERB
easat-284	78	22	.	.	PUNCT
easat-284	79	1	the	the	DET
easat-284	79	2	alveolar	alveolar	ADJ
easat-284	79	3	phase	phase	NOUN
easat-284	79	4	is	be	AUX
easat-284	79	5	evolving	evolve	VERB
easat-284	79	6	in	in	ADP
easat-284	79	7	2	2	NUM
easat-284	79	8	different	different	ADJ
easat-284	79	9	patterns	pattern	NOUN
easat-284	79	10	:	:	PUNCT
easat-284	79	11	3a	3a	NUM
easat-284	79	12	)	)	PUNCT
easat-284	79	13	moderate	moderate	ADJ
easat-284	79	14	with	with	ADP
easat-284	79	15	absent	absent	ADJ
easat-284	79	16	or	or	CCONJ
easat-284	79	17	minor	minor	ADJ
easat-284	79	18	endothelial	endothelial	ADJ
easat-284	79	19	leakage	leakage	NOUN
easat-284	79	20	,	,	PUNCT
easat-284	79	21	3b	3b	NUM
easat-284	79	22	)	)	PUNCT
easat-284	79	23	severe	severe	ADJ
easat-284	79	24	with	with	ADP
easat-284	79	25	alveolar	alveolar	ADJ
easat-284	79	26	collapse	collapse	NOUN
easat-284	79	27	due	due	ADP
easat-284	79	28	to	to	ADP
easat-284	79	29	surfactant	surfactant	ADJ
easat-284	79	30	loss	loss	NOUN
easat-284	79	31	,	,	PUNCT
easat-284	79	32	fluid	fluid	ADJ
easat-284	79	33	filling	filling	NOUN
easat-284	79	34	of	of	ADP
easat-284	79	35	interstitium	interstitium	NOUN
easat-284	79	36	,	,	PUNCT
easat-284	79	37	engulfing	engulf	VERB
easat-284	79	38	protein	protein	NOUN
easat-284	79	39	-	-	PUNCT
easat-284	79	40	rich	rich	ADJ
easat-284	79	41	fluid	fluid	NOUN
easat-284	79	42	with	with	ADP
easat-284	79	43	neutrophils	neutrophil	NOUN
easat-284	79	44	release	release	NOUN
easat-284	79	45	products	product	NOUN
easat-284	79	46	like	like	ADP
easat-284	79	47	nets	net	NOUN
easat-284	79	48	,	,	PUNCT
easat-284	79	49	reduced	reduce	VERB
easat-284	79	50	gas	gas	NOUN
easat-284	79	51	exchange	exchange	NOUN
easat-284	79	52	,	,	PUNCT
easat-284	79	53	endothelial	endothelial	ADJ
easat-284	79	54	lesion	lesion	NOUN
easat-284	79	55	,	,	PUNCT
easat-284	79	56	through	through	ADP
easat-284	79	57	which	which	PRON
easat-284	79	58	sars	sar	NOUN
easat-284	79	59	-	-	PUNCT
easat-284	79	60	cov-2	cov-2	PART
easat-284	79	61	virus	virus	NOUN
easat-284	79	62	can	can	AUX
easat-284	79	63	enter	enter	VERB
easat-284	79	64	into	into	ADP
easat-284	79	65	the	the	DET
easat-284	79	66	bloodstream	bloodstream	NOUN
easat-284	79	67	and	and	CCONJ
easat-284	79	68	induce	induce	VERB
easat-284	79	69	viral	viral	ADJ
easat-284	79	70	sepsis	sepsis	NOUN
easat-284	79	71	.	.	PUNCT
easat-284	80	1	in	in	ADP
easat-284	80	2	sars	sars	PROPN
easat-284	80	3	-	-	PUNCT
easat-284	80	4	cov-2	cov-2	NOUN
easat-284	80	5	infected	infected	ADJ
easat-284	80	6	lung	lung	NOUN
easat-284	80	7	cells	cell	NOUN
easat-284	80	8	,	,	PUNCT
easat-284	80	9	deposits	deposit	NOUN
easat-284	80	10	of	of	ADP
easat-284	80	11	terminal	terminal	ADJ
easat-284	80	12	complement	complement	NOUN
easat-284	80	13	components	component	NOUN
easat-284	80	14	c5b-9	c5b-9	PROPN
easat-284	80	15	,	,	PUNCT
easat-284	80	16	c4d	c4d	PROPN
easat-284	80	17	and	and	CCONJ
easat-284	80	18	masp2	masp2	PROPN
easat-284	80	19	attack	attack	VERB
easat-284	80	20	the	the	DET
easat-284	80	21	host	host	NOUN
easat-284	80	22	ecs	ec	NOUN
easat-284	80	23	and	and	CCONJ
easat-284	80	24	cause	cause	VERB
easat-284	80	25	transmembrane	transmembrane	ADJ
easat-284	80	26	channel	channel	NOUN
easat-284	80	27	formation	formation	NOUN
easat-284	80	28	on	on	ADP
easat-284	80	29	the	the	DET
easat-284	80	30	endothelium	endothelium	NOUN
easat-284	80	31	and	and	CCONJ
easat-284	80	32	induce	induce	VERB
easat-284	80	33	endotheliopathy	endotheliopathy	ADJ
easat-284	80	34	,	,	PUNCT
easat-284	80	35	involved	involve	VERB
easat-284	80	36	in	in	ADP
easat-284	80	37	ards	ard	NOUN
easat-284	80	38	like	like	ADP
easat-284	80	39	syndrome	syndrome	NOUN
easat-284	80	40	with	with	ADP
easat-284	80	41	systemic	systemic	ADJ
easat-284	80	42	inflammation	inflammation	NOUN
easat-284	80	43	and	and	CCONJ
easat-284	80	44	lung	lung	NOUN
easat-284	80	45	neutrophilia	neutrophilia	PROPN
easat-284	81	1	[	[	X
easat-284	81	2	28	28	NUM
easat-284	81	3	]	]	PUNCT
easat-284	81	4	.	.	PUNCT
easat-284	82	1	a	a	DET
easat-284	82	2	similar	similar	ADJ
easat-284	82	3	pattern	pattern	NOUN
easat-284	82	4	has	have	AUX
easat-284	82	5	been	be	AUX
easat-284	82	6	shown	show	VERB
easat-284	82	7	in	in	ADP
easat-284	82	8	purpuric	purpuric	ADJ
easat-284	82	9	skin	skin	NOUN
easat-284	82	10	lesions	lesion	NOUN
easat-284	82	11	due	due	ADP
easat-284	82	12	to	to	ADP
easat-284	82	13	a	a	DET
easat-284	82	14	pauciinflammatory	pauciinflammatory	ADJ
easat-284	82	15	thrombogenic	thrombogenic	ADJ
easat-284	82	16	vasculopathy	vasculopathy	NOUN
easat-284	82	17	,	,	PUNCT
easat-284	82	18	with	with	ADP
easat-284	82	19	co	co	NOUN
easat-284	82	20	-	-	NOUN
easat-284	82	21	localization	localization	NOUN
easat-284	82	22	of	of	ADP
easat-284	82	23	covid-19	covid-19	PROPN
easat-284	82	24	spike	spike	ADJ
easat-284	82	25	glycoproteins	glycoprotein	NOUN
easat-284	82	26	and	and	CCONJ
easat-284	82	27	deposition	deposition	NOUN
easat-284	82	28	of	of	ADP
easat-284	82	29	c5b-9	c5b-9	PROPN
easat-284	82	30	and	and	CCONJ
easat-284	82	31	c4d	c4d	PROPN
easat-284	82	32	in	in	ADP
easat-284	82	33	both	both	PRON
easat-284	82	34	grossly	grossly	ADV
easat-284	82	35	involved	involved	ADJ
easat-284	82	36	and	and	CCONJ
easat-284	82	37	normally	normally	ADV
easat-284	82	38	-	-	PUNCT
easat-284	82	39	appearing	appear	VERB
easat-284	82	40	skin	skin	NOUN
easat-284	82	41	and	and	CCONJ
easat-284	82	42	in	in	ADP
easat-284	82	43	lung	lung	NOUN
easat-284	82	44	interalveolar	interalveolar	ADJ
easat-284	82	45	septa	septum	NOUN
easat-284	82	46	[	[	X
easat-284	82	47	29	29	NUM
easat-284	82	48	]	]	PUNCT
easat-284	82	49	.	.	PUNCT
easat-284	83	1	platelets	platelet	NOUN
easat-284	83	2	also	also	ADV
easat-284	83	3	play	play	VERB
easat-284	83	4	a	a	DET
easat-284	83	5	critical	critical	ADJ
easat-284	83	6	role	role	NOUN
easat-284	83	7	in	in	ADP
easat-284	83	8	lung	lung	NOUN
easat-284	83	9	innate	innate	ADJ
easat-284	83	10	defense	defense	NOUN
easat-284	83	11	response	response	NOUN
easat-284	83	12	,	,	PUNCT
easat-284	83	13	being	be	AUX
easat-284	83	14	lung	lung	NOUN
easat-284	83	15	a	a	DET
easat-284	83	16	primary	primary	ADJ
easat-284	83	17	site	site	NOUN
easat-284	83	18	for	for	ADP
easat-284	83	19	platelet	platelet	NOUN
easat-284	83	20	biogenesis	biogenesis	NOUN
easat-284	83	21	:	:	PUNCT
easat-284	83	22	activated	activate	VERB
easat-284	83	23	platelets	platelet	NOUN
easat-284	83	24	engulf	engulf	NOUN
easat-284	83	25	virions	virion	NOUN
easat-284	83	26	and	and	CCONJ
easat-284	83	27	secrete	secrete	VERB
easat-284	83	28	an	an	DET
easat-284	83	29	tiviral	tiviral	ADJ
easat-284	83	30	molecules	molecule	NOUN
easat-284	83	31	(	(	PUNCT
easat-284	83	32	example	example	NOUN
easat-284	83	33	:	:	PUNCT
easat-284	83	34	a	a	DET
easat-284	83	35	-	-	PUNCT
easat-284	83	36	granules	granule	NOUN
easat-284	83	37	)	)	PUNCT
easat-284	83	38	to	to	PART
easat-284	83	39	destroy	destroy	VERB
easat-284	83	40	virions	virion	NOUN
easat-284	83	41	,	,	PUNCT
easat-284	83	42	hmgb1	hmgb1	NOUN
easat-284	83	43	and	and	CCONJ
easat-284	83	44	express	express	VERB
easat-284	83	45	surface	surface	NOUN
easat-284	83	46	p	p	NOUN
easat-284	83	47	-	-	PUNCT
easat-284	83	48	selectin	selectin	NOUN
easat-284	83	49	enabling	enable	VERB
easat-284	83	50	the	the	DET
easat-284	83	51	initial	initial	ADJ
easat-284	83	52	attachment	attachment	NOUN
easat-284	83	53	of	of	ADP
easat-284	83	54	neutrophils	neutrophil	NOUN
easat-284	83	55	from	from	ADP
easat-284	83	56	the	the	DET
easat-284	83	57	bloodstream	bloodstream	NOUN
easat-284	83	58	[	[	X
easat-284	83	59	29	29	NUM
easat-284	83	60	]	]	PUNCT
easat-284	83	61	(	(	PUNCT
easat-284	83	62	figure	figure	NOUN
easat-284	83	63	3	3	NUM
easat-284	83	64	)	)	PUNCT
easat-284	83	65	.	.	PUNCT
easat-284	84	1	69	69	NUM
easat-284	84	2	edelweiss	edelweiss	PROPN
easat-284	84	3	applied	apply	VERB
easat-284	84	4	science	science	NOUN
easat-284	84	5	and	and	CCONJ
easat-284	84	6	technology	technology	NOUN
easat-284	84	7	issn	issn	PROPN
easat-284	84	8	:	:	PUNCT
easat-284	84	9	2576	2576	NUM
easat-284	84	10	-	-	SYM
easat-284	84	11	8484	8484	NUM
easat-284	84	12	vol	vol	NOUN
easat-284	84	13	.	.	PROPN
easat-284	85	1	4	4	NUM
easat-284	85	2	,	,	PUNCT
easat-284	85	3	no	no	INTJ
easat-284	85	4	.	.	NOUN
easat-284	85	5	1	1	NUM
easat-284	85	6	:	:	SYM
easat-284	85	7	67	67	NUM
easat-284	85	8	-	-	SYM
easat-284	85	9	73	73	NUM
easat-284	85	10	,	,	PUNCT
easat-284	85	11	2020	2020	NUM
easat-284	85	12	doi	doi	NOUN
easat-284	85	13	:	:	PUNCT
easat-284	85	14	10.33805/2576	10.33805/2576	NUM
easat-284	85	15	-	-	SYM
easat-284	85	16	8484.184	8484.184	NUM
easat-284	85	17	©	©	PROPN
easat-284	85	18	2020	2020	NUM
easat-284	85	19	by	by	ADP
easat-284	85	20	the	the	DET
easat-284	85	21	author	author	NOUN
easat-284	85	22	figure	figure	NOUN
easat-284	86	1	3	3	NUM
easat-284	86	2	.	.	PUNCT
easat-284	86	3	a	a	X
easat-284	86	4	)	)	PUNCT
easat-284	86	5	viral	viral	ADJ
easat-284	86	6	infection	infection	NOUN
easat-284	86	7	,	,	PUNCT
easat-284	86	8	b	b	NOUN
easat-284	86	9	)	)	PUNCT
easat-284	86	10	activation	activation	NOUN
easat-284	86	11	of	of	ADP
easat-284	86	12	inflammatory	inflammatory	ADJ
easat-284	86	13	response	response	NOUN
easat-284	86	14	proteins	protein	NOUN
easat-284	86	15	,	,	PUNCT
easat-284	86	16	c	c	NOUN
easat-284	86	17	)	)	PUNCT
easat-284	86	18	neutrophil	neutrophil	ADJ
easat-284	86	19	recruitment	recruitment	NOUN
easat-284	86	20	,	,	PUNCT
easat-284	86	21	d	d	NOUN
easat-284	86	22	)	)	PUNCT
easat-284	86	23	proteolytic	proteolytic	ADJ
easat-284	86	24	cascades	cascade	NOUN
easat-284	86	25	imbalance	imbalance	NOUN
easat-284	86	26	,	,	PUNCT
easat-284	86	27	e	e	NOUN
easat-284	86	28	)	)	PUNCT
easat-284	86	29	endotheliopathy	endotheliopathy	ADJ
easat-284	86	30	and	and	CCONJ
easat-284	86	31	nets	net	NOUN
easat-284	86	32	.	.	PUNCT
easat-284	87	1	the	the	DET
easat-284	87	2	neutrophils	neutrophil	NOUN
easat-284	87	3	“	"	PUNCT
easat-284	87	4	friendly	friendly	ADJ
easat-284	87	5	fire	fire	NOUN
easat-284	87	6	”	"	PUNCT
easat-284	87	7	,	,	PUNCT
easat-284	87	8	the	the	DET
easat-284	87	9	netosis	netosis	NOUN
easat-284	87	10	and	and	CCONJ
easat-284	87	11	the	the	DET
easat-284	87	12	proteolytic	proteolytic	ADJ
easat-284	87	13	storm	storm	NOUN
easat-284	87	14	.	.	PUNCT
easat-284	88	1	dangerous	dangerous	ADJ
easat-284	88	2	not	not	PART
easat-284	88	3	inhibited	inhibit	VERB
easat-284	88	4	partnership	partnership	NOUN
easat-284	88	5	of	of	ADP
easat-284	88	6	platelets	platelet	NOUN
easat-284	88	7	,	,	PUNCT
easat-284	88	8	complement	complement	NOUN
easat-284	88	9	and	and	CCONJ
easat-284	88	10	coagulation	coagulation	NOUN
easat-284	88	11	cascades	cascade	NOUN
easat-284	88	12	for	for	ADP
easat-284	88	13	endotheliopathy	endotheliopathy	ADJ
easat-284	88	14	and	and	CCONJ
easat-284	88	15	thrombogenesis	thrombogenesis	NOUN
easat-284	88	16	:	:	PUNCT
easat-284	88	17	the	the	DET
easat-284	88	18	lung	lung	NOUN
easat-284	88	19	alveoli	alveolus	NOUN
easat-284	88	20	are	be	AUX
easat-284	88	21	thus	thus	ADV
easat-284	88	22	the	the	DET
easat-284	88	23	last	last	ADJ
easat-284	88	24	defense	defense	NOUN
easat-284	88	25	line	line	NOUN
easat-284	88	26	against	against	ADP
easat-284	88	27	sars	sar	NOUN
easat-284	88	28	-	-	PUNCT
easat-284	88	29	cov-2	cov-2	NOUN
easat-284	88	30	bloodstream	bloodstream	NOUN
easat-284	88	31	dissemination	dissemination	NOUN
easat-284	88	32	and	and	CCONJ
easat-284	88	33	viral	viral	ADJ
easat-284	88	34	sepsis	sepsis	NOUN
easat-284	88	35	and	and	CCONJ
easat-284	88	36	thus	thus	ADV
easat-284	88	37	innate	innate	ADJ
easat-284	88	38	immunology	immunology	NOUN
easat-284	88	39	is	be	AUX
easat-284	88	40	highly	highly	ADV
easat-284	88	41	involved	involved	ADJ
easat-284	88	42	in	in	ADP
easat-284	88	43	fighting	fight	VERB
easat-284	88	44	.	.	PUNCT
easat-284	89	1	in	in	ADP
easat-284	89	2	severe	severe	ADJ
easat-284	89	3	covid-19	covid-19	PROPN
easat-284	89	4	,	,	PUNCT
easat-284	89	5	neutrophils	neutrophil	NOUN
easat-284	89	6	,	,	PUNCT
easat-284	89	7	together	together	ADV
easat-284	89	8	with	with	ADP
easat-284	89	9	other	other	ADJ
easat-284	89	10	mononuclear	mononuclear	ADJ
easat-284	89	11	,	,	PUNCT
easat-284	89	12	are	be	AUX
easat-284	89	13	the	the	DET
easat-284	89	14	first	first	ADJ
easat-284	89	15	cells	cell	NOUN
easat-284	89	16	of	of	ADP
easat-284	89	17	the	the	DET
easat-284	89	18	immune	immune	ADJ
easat-284	89	19	system	system	NOUN
easat-284	89	20	to	to	PART
easat-284	89	21	migrate	migrate	VERB
easat-284	89	22	to	to	ADP
easat-284	89	23	the	the	DET
easat-284	89	24	infected	infected	ADJ
easat-284	89	25	alveoli	alveoli	NOUN
easat-284	89	26	,	,	PUNCT
easat-284	89	27	recruited	recruit	VERB
easat-284	89	28	by	by	ADP
easat-284	89	29	interferons	interferon	NOUN
easat-284	89	30	,	,	PUNCT
easat-284	89	31	il-1β	il-1β	PROPN
easat-284	89	32	and	and	CCONJ
easat-284	89	33	il-6	il-6	NOUN
easat-284	89	34	,	,	PUNCT
easat-284	89	35	where	where	SCONJ
easat-284	89	36	they	they	PRON
easat-284	89	37	attack	attack	VERB
easat-284	89	38	sars	sar	NOUN
easat-284	89	39	-	-	PUNCT
easat-284	89	40	cov-2	cov-2	NOUN
easat-284	89	41	,	,	PUNCT
easat-284	89	42	but	but	CCONJ
easat-284	89	43	in	in	ADP
easat-284	89	44	addition	addition	NOUN
easat-284	89	45	to	to	ADP
easat-284	89	46	direct	direct	ADJ
easat-284	89	47	virus	virus	NOUN
easat-284	89	48	-	-	PUNCT
easat-284	89	49	inflicted	inflict	VERB
easat-284	89	50	pathologies	pathology	NOUN
easat-284	89	51	,	,	PUNCT
easat-284	89	52	their	their	PRON
easat-284	89	53	exaggerated	exaggerated	ADJ
easat-284	89	54	“	"	PUNCT
easat-284	89	55	unfriendly	unfriendly	ADJ
easat-284	89	56	fire	fire	NOUN
easat-284	89	57	”	"	PUNCT
easat-284	89	58	responses	response	NOUN
easat-284	89	59	,	,	PUNCT
easat-284	89	60	resulting	result	VERB
easat-284	89	61	in	in	ADP
easat-284	89	62	a	a	DET
easat-284	89	63	“	"	PUNCT
easat-284	89	64	proteolytic	proteolytic	ADJ
easat-284	89	65	storm	storm	NOUN
easat-284	89	66	”	"	PUNCT
easat-284	89	67	and	and	CCONJ
easat-284	89	68	,	,	PUNCT
easat-284	89	69	inducing	induce	VERB
easat-284	89	70	alveolar	alveolar	ADJ
easat-284	89	71	capilla	capilla	NOUN
easat-284	89	72	ry	ry	X
easat-284	89	73	endotheliopathy	endotheliopathy	ADJ
easat-284	89	74	,	,	PUNCT
easat-284	89	75	contribute	contribute	VERB
easat-284	89	76	to	to	ADP
easat-284	89	77	disease	disease	NOUN
easat-284	89	78	severity	severity	NOUN
easat-284	89	79	and	and	CCONJ
easat-284	89	80	subsequent	subsequent	ADJ
easat-284	89	81	viral	viral	ADJ
easat-284	89	82	dissemination	dissemination	NOUN
easat-284	89	83	[	[	X
easat-284	89	84	16	16	NUM
easat-284	89	85	,	,	PUNCT
easat-284	89	86	30	30	NUM
easat-284	89	87	]	]	PUNCT
easat-284	89	88	.	.	PUNCT
easat-284	90	1	the	the	DET
easat-284	90	2	mechanisms	mechanism	NOUN
easat-284	90	3	that	that	PRON
easat-284	90	4	neutrophils	neutrophil	NOUN
easat-284	90	5	undertake	undertake	VERB
easat-284	90	6	for	for	ADP
easat-284	90	7	host	host	NOUN
easat-284	90	8	defense	defense	NOUN
easat-284	90	9	are	be	AUX
easat-284	90	10	phagocytosis	phagocytosis	NOUN
easat-284	90	11	,	,	PUNCT
easat-284	90	12	degranulation	degranulation	NOUN
easat-284	90	13	,	,	PUNCT
easat-284	90	14	cytokine	cytokine	ADJ
easat-284	90	15	production	production	NOUN
easat-284	90	16	and	and	CCONJ
easat-284	90	17	neutrophil	neutrophil	ADJ
easat-284	90	18	extracellular	extracellular	ADJ
easat-284	90	19	traps	trap	NOUN
easat-284	90	20	(	(	PUNCT
easat-284	90	21	nets	net	NOUN
easat-284	90	22	)	)	PUNCT
easat-284	90	23	release	release	NOUN
easat-284	90	24	,	,	PUNCT
easat-284	90	25	known	know	VERB
easat-284	90	26	as	as	ADP
easat-284	90	27	netosis	netosis	NOUN
easat-284	90	28	.	.	PUNCT
easat-284	91	1	neutrophil	neutrophil	ADJ
easat-284	91	2	extracellular	extracellular	ADJ
easat-284	91	3	traps	trap	NOUN
easat-284	91	4	are	be	AUX
easat-284	91	5	dna	dna	PROPN
easat-284	91	6	structures	structure	NOUN
easat-284	91	7	released	release	VERB
easat-284	91	8	including	include	VERB
easat-284	91	9	histones	histone	NOUN
easat-284	91	10	and	and	CCONJ
easat-284	91	11	over	over	ADP
easat-284	91	12	30	30	NUM
easat-284	91	13	components	component	NOUN
easat-284	91	14	of	of	ADP
easat-284	91	15	pri	pri	PROPN
easat-284	91	16	mary	mary	PROPN
easat-284	91	17	and	and	CCONJ
easat-284	91	18	secondary	secondary	ADJ
easat-284	91	19	granules	granule	NOUN
easat-284	91	20	,	,	PUNCT
easat-284	91	21	such	such	ADJ
easat-284	91	22	as	as	ADP
easat-284	91	23	elastase	elastase	NOUN
easat-284	91	24	,	,	PUNCT
easat-284	91	25	myeloperoxidase	myeloperoxidase	NOUN
easat-284	91	26	,	,	PUNCT
easat-284	91	27	cathepsin	cathepsin	NOUN
easat-284	91	28	g	g	PROPN
easat-284	91	29	(	(	PUNCT
easat-284	91	30	cg	cg	NOUN
easat-284	91	31	)	)	PUNCT
easat-284	91	32	,	,	PUNCT
easat-284	91	33	lactoferrin	lactoferrin	NOUN
easat-284	91	34	,	,	PUNCT
easat-284	91	35	pentraxin	pentraxin	NOUN
easat-284	91	36	3	3	NUM
easat-284	91	37	,	,	PUNCT
easat-284	91	38	gelatinase	gelatinase	NOUN
easat-284	91	39	,	,	PUNCT
easat-284	91	40	proteinase	proteinase	NOUN
easat-284	91	41	3	3	NUM
easat-284	91	42	,	,	PUNCT
easat-284	91	43	ll37	ll37	PROPN
easat-284	91	44	and	and	CCONJ
easat-284	91	45	peptidoglycan	peptidoglycan	ADJ
easat-284	91	46	-	-	PUNCT
easat-284	91	47	binding	bind	VERB
easat-284	91	48	proteins	protein	NOUN
easat-284	91	49	.	.	PUNCT
easat-284	92	1	three	three	NUM
easat-284	92	2	models	model	NOUN
easat-284	92	3	for	for	ADP
easat-284	92	4	netosis	netosis	NOUN
easat-284	92	5	are	be	AUX
easat-284	92	6	known	know	VERB
easat-284	92	7	to	to	ADP
easat-284	92	8	date	date	NOUN
easat-284	92	9	:	:	PUNCT
easat-284	92	10	suicidal	suicidal	ADJ
easat-284	92	11	(	(	PUNCT
easat-284	92	12	nets	net	NOUN
easat-284	92	13	release	release	NOUN
easat-284	92	14	and	and	CCONJ
easat-284	92	15	neutrophil	neutrophil	ADJ
easat-284	92	16	lysis	lysis	NOUN
easat-284	92	17	)	)	PUNCT
easat-284	92	18	,	,	PUNCT
easat-284	92	19	vital	vital	ADJ
easat-284	92	20	netosis	netosis	NOUN
easat-284	92	21	(	(	PUNCT
easat-284	92	22	triggered	trigger	VERB
easat-284	92	23	by	by	ADP
easat-284	92	24	tlrs	tlrs	ADJ
easat-284	92	25	stimuli	stimulus	NOUN
easat-284	92	26	,	,	PUNCT
easat-284	92	27	platelet	platelet	NOUN
easat-284	92	28	glycoprotein	glycoprotein	NOUN
easat-284	92	29	ib	ib	NOUN
easat-284	92	30	,	,	PUNCT
easat-284	92	31	complement	complement	NOUN
easat-284	92	32	activation	activation	NOUN
easat-284	92	33	,	,	PUNCT
easat-284	92	34	after	after	SCONJ
easat-284	92	35	release	release	NOUN
easat-284	92	36	neutrophils	neutrophil	NOUN
easat-284	92	37	are	be	AUX
easat-284	92	38	still	still	ADV
easat-284	92	39	able	able	ADJ
easat-284	92	40	to	to	PART
easat-284	92	41	phagocytose	phagocytose	VERB
easat-284	92	42	pathogens	pathogen	NOUN
easat-284	92	43	and	and	CCONJ
easat-284	92	44	have	have	VERB
easat-284	92	45	a	a	DET
easat-284	92	46	normal	normal	ADJ
easat-284	92	47	lifespan	lifespan	NOUN
easat-284	92	48	)	)	PUNCT
easat-284	92	49	and	and	CCONJ
easat-284	92	50	mitochondrial	mitochondrial	ADJ
easat-284	92	51	dna	dna	NOUN
easat-284	92	52	is	be	AUX
easat-284	92	53	released	release	VERB
easat-284	92	54	instead	instead	ADV
easat-284	92	55	of	of	ADP
easat-284	92	56	nuclear	nuclear	ADJ
easat-284	92	57	dna	dna	NOUN
easat-284	93	1	[	[	X
easat-284	93	2	31	31	NUM
easat-284	93	3	]	]	PUNCT
easat-284	93	4	.	.	PUNCT
easat-284	94	1	platelet	platelet	NOUN
easat-284	94	2	hmgb1	hmgb1	PROPN
easat-284	94	3	protein	protein	NOUN
easat-284	94	4	(	(	PUNCT
easat-284	94	5	passively	passively	ADV
easat-284	94	6	released	release	VERB
easat-284	94	7	extracellularly	extracellularly	ADV
easat-284	94	8	as	as	ADP
easat-284	94	9	a	a	DET
easat-284	94	10	prototypical	prototypical	ADJ
easat-284	94	11	damp	damp	NOUN
easat-284	94	12	from	from	ADP
easat-284	94	13	dying	die	VERB
easat-284	94	14	cells	cell	NOUN
easat-284	94	15	or	or	CCONJ
easat-284	94	16	stressed	stress	VERB
easat-284	94	17	or	or	CCONJ
easat-284	94	18	activated	activate	VERB
easat-284	94	19	cells	cell	NOUN
easat-284	94	20	present	present	ADJ
easat-284	94	21	in	in	ADP
easat-284	94	22	any	any	DET
easat-284	94	23	tissue	tissue	NOUN
easat-284	94	24	)	)	PUNCT
easat-284	94	25	is	be	AUX
easat-284	94	26	the	the	DET
easat-284	94	27	major	major	ADJ
easat-284	94	28	endogenous	endogenous	ADJ
easat-284	94	29	inducer	inducer	NOUN
easat-284	94	30	of	of	ADP
easat-284	94	31	nets	net	NOUN
easat-284	94	32	formation	formation	NOUN
easat-284	94	33	.	.	PUNCT
easat-284	95	1	net	net	ADJ
easat-284	95	2	chromatin	chromatin	NOUN
easat-284	95	3	disrupts	disrupt	VERB
easat-284	95	4	epithelial	epithelial	ADJ
easat-284	95	5	lining	lining	NOUN
easat-284	95	6	,	,	PUNCT
easat-284	95	7	induces	induce	VERB
easat-284	95	8	platelet	platelet	NOUN
easat-284	95	9	aggregation	aggregation	NOUN
easat-284	95	10	and	and	CCONJ
easat-284	95	11	activates	activate	VERB
easat-284	95	12	further	further	ADJ
easat-284	95	13	neutrophils	neutrophil	NOUN
easat-284	95	14	recruitment	recruitment	NOUN
easat-284	95	15	[	[	X
easat-284	95	16	32	32	NUM
easat-284	95	17	]	]	PUNCT
easat-284	95	18	.	.	PUNCT
easat-284	96	1	nets	net	NOUN
easat-284	96	2	,	,	PUNCT
easat-284	96	3	via	via	ADP
easat-284	96	4	electrostatic	electrostatic	ADJ
easat-284	96	5	interactions	interaction	NOUN
easat-284	96	6	,	,	PUNCT
easat-284	96	7	activate	activate	VERB
easat-284	96	8	the	the	DET
easat-284	96	9	contact	contact	NOUN
easat-284	96	10	pathway	pathway	NOUN
easat-284	96	11	of	of	ADP
easat-284	96	12	coagulation	coagulation	NOUN
easat-284	96	13	and	and	CCONJ
easat-284	96	14	,	,	PUNCT
easat-284	96	15	through	through	ADP
easat-284	96	16	tissue	tissue	NOUN
easat-284	96	17	factor	factor	NOUN
easat-284	96	18	,	,	PUNCT
easat-284	96	19	the	the	DET
easat-284	96	20	intrinsic	intrinsic	ADJ
easat-284	96	21	pathway	pathway	NOUN
easat-284	96	22	[	[	X
easat-284	96	23	30	30	NUM
easat-284	96	24	,	,	PUNCT
easat-284	96	25	33	33	NUM
easat-284	96	26	]	]	PUNCT
easat-284	96	27	.	.	PUNCT
easat-284	97	1	nets	net	NOUN
easat-284	97	2	form	form	VERB
easat-284	97	3	a	a	DET
easat-284	97	4	scaffold	scaffold	NOUN
easat-284	97	5	for	for	ADP
easat-284	97	6	thrombus	thrombus	NOUN
easat-284	97	7	formation	formation	NOUN
easat-284	97	8	by	by	ADP
easat-284	97	9	promoting	promote	VERB
easat-284	97	10	platelet	platelet	NOUN
easat-284	97	11	adhesion	adhesion	NOUN
easat-284	97	12	and	and	CCONJ
easat-284	97	13	by	by	ADP
easat-284	97	14	concentrating	concentrate	VERB
easat-284	97	15	coagulation	coagulation	NOUN
easat-284	97	16	factors	factor	NOUN
easat-284	97	17	involved	involve	VERB
easat-284	97	18	in	in	ADP
easat-284	97	19	clotting	clot	VERB
easat-284	97	20	.	.	PUNCT
easat-284	98	1	thrombus	thrombus	ADJ
easat-284	98	2	-	-	PUNCT
easat-284	98	3	resident	resident	ADJ
easat-284	98	4	neutrophils	neutrophil	NOUN
easat-284	98	5	are	be	AUX
easat-284	98	6	strategic	strategic	ADJ
easat-284	98	7	for	for	ADP
easat-284	98	8	thrombi	thrombi	NOUN
easat-284	98	9	extension	extension	NOUN
easat-284	98	10	by	by	ADP
easat-284	98	11	binding	binding	ADJ
easat-284	98	12	factor	factor	NOUN
easat-284	98	13	xii	xii	NOUN
easat-284	98	14	and	and	CCONJ
easat-284	98	15	supporting	support	VERB
easat-284	98	16	its	its	PRON
easat-284	98	17	activation	activation	NOUN
easat-284	98	18	through	through	ADP
easat-284	98	19	netosis	netosis	NOUN
easat-284	98	20	[	[	X
easat-284	98	21	34	34	NUM
easat-284	98	22	]	]	PUNCT
easat-284	98	23	.	.	PUNCT
easat-284	99	1	the	the	DET
easat-284	99	2	endothelial	endothelial	ADJ
easat-284	99	3	cells	cell	NOUN
easat-284	99	4	damage	damage	NOUN
easat-284	99	5	(	(	PUNCT
easat-284	99	6	endotheliopathy	endotheliopathy	ADJ
easat-284	99	7	)	)	PUNCT
easat-284	99	8	,	,	PUNCT
easat-284	99	9	induced	induce	VERB
easat-284	99	10	by	by	ADP
easat-284	99	11	sars	sar	NOUN
easat-284	99	12	-	-	PUNCT
easat-284	99	13	cov-2	cov-2	PART
easat-284	99	14	virus	virus	NOUN
easat-284	99	15	and	and	CCONJ
easat-284	99	16	neutrophil	neutrophil	ADJ
easat-284	99	17	elastase	elastase	NOUN
easat-284	99	18	,	,	PUNCT
easat-284	99	19	triggers	trigger	VERB
easat-284	99	20	the	the	DET
easat-284	99	21	activation	activation	NOUN
easat-284	99	22	of	of	ADP
easat-284	99	23	two	two	NUM
easat-284	99	24	independent	independent	ADJ
easat-284	99	25	endothelial	endothelial	ADJ
easat-284	99	26	pathways	pathway	NOUN
easat-284	99	27	(	(	PUNCT
easat-284	99	28	inflammatory	inflammatory	ADJ
easat-284	99	29	and	and	CCONJ
easat-284	99	30	microthrombotic	microthrombotic	ADJ
easat-284	99	31	)	)	PUNCT
easat-284	99	32	,	,	PUNCT
easat-284	99	33	through	through	ADP
easat-284	99	34	release	release	NOUN
easat-284	99	35	of	of	ADP
easat-284	99	36	inflammatory	inflammatory	ADJ
easat-284	99	37	cytokines	cytokine	NOUN
easat-284	99	38	(	(	PUNCT
easat-284	99	39	interleukin	interleukin	NOUN
easat-284	99	40	il	il	PROPN
easat-284	99	41	-1	-1	PROPN
easat-284	99	42	,	,	PUNCT
easat-284	99	43	il-6	il-6	NUM
easat-284	99	44	,	,	PUNCT
easat-284	99	45	tumor	tumor	NOUN
easat-284	99	46	necrosis	necrosis	NOUN
easat-284	99	47	factor	factor	NOUN
easat-284	99	48	-	-	PUNCT
easat-284	99	49	α	α	NOUN
easat-284	99	50	,	,	PUNCT
easat-284	99	51	and	and	CCONJ
easat-284	99	52	others	other	NOUN
easat-284	99	53	)	)	PUNCT
easat-284	99	54	and	and	CCONJ
easat-284	99	55	activation	activation	NOUN
easat-284	99	56	of	of	ADP
easat-284	99	57	the	the	DET
easat-284	99	58	platelet	platelet	NOUN
easat-284	99	59	and	and	CCONJ
easat-284	99	60	endothelial	endothelial	ADJ
easat-284	99	61	exocytosis	exocytosis	NOUN
easat-284	99	62	of	of	ADP
easat-284	99	63	ulvwf	ulvwf	NOUN
easat-284	99	64	,	,	PUNCT
easat-284	99	65	mediating	mediate	VERB
easat-284	99	66	microthrombogenesis	microthrombogenesis	NOUN
easat-284	99	67	via	via	ADP
easat-284	99	68	“	"	PUNCT
easat-284	99	69	activation	activation	NOUN
easat-284	99	70	of	of	ADP
easat-284	99	71	microthrombotic	microthrombotic	ADJ
easat-284	99	72	pathway	pathway	NOUN
easat-284	99	73	”	"	PUNCT
easat-284	99	74	.	.	PUNCT
easat-284	100	1	in	in	ADP
easat-284	100	2	parallel	parallel	ADJ
easat-284	100	3	endothelial	endothelial	ADJ
easat-284	100	4	damage	damage	NOUN
easat-284	100	5	inhibits	inhibit	VERB
easat-284	100	6	adamts13	adamts13	NOUN
easat-284	100	7	biosynthesis	biosynthesis	NOUN
easat-284	100	8	,	,	PUNCT
easat-284	100	9	while	while	SCONJ
easat-284	100	10	neutrophil	neutrophil	ADJ
easat-284	100	11	elastase	elastase	NOUN
easat-284	100	12	proteolytically	proteolytically	ADV
easat-284	100	13	cleaves	cleave	VERB
easat-284	100	14	and	and	CCONJ
easat-284	100	15	significantly	significantly	ADV
easat-284	100	16	decreases	decrease	VERB
easat-284	100	17	its	its	PRON
easat-284	100	18	plasma	plasma	NOUN
easat-284	100	19	level	level	NOUN
easat-284	100	20	[	[	X
easat-284	100	21	35	35	NUM
easat-284	100	22	]	]	PUNCT
easat-284	100	23	.	.	PUNCT
easat-284	101	1	fxia	fxia	NOUN
easat-284	101	2	and	and	CCONJ
easat-284	101	3	α	α	NOUN
easat-284	101	4	-	-	ADJ
easat-284	101	5	thrombin	thrombin	NOUN
easat-284	101	6	remove	remove	VERB
easat-284	101	7	c	c	NOUN
easat-284	101	8	-	-	PUNCT
easat-284	101	9	terminal	terminal	ADJ
easat-284	101	10	domain	domain	NOUN
easat-284	101	11	of	of	ADP
easat-284	101	12	adamts13	adamts13	NOUN
easat-284	101	13	,	,	PUNCT
easat-284	101	14	blocking	block	VERB
easat-284	101	15	its	its	PRON
easat-284	101	16	ability	ability	NOUN
easat-284	101	17	to	to	PART
easat-284	101	18	cleave	cleave	VERB
easat-284	101	19	vwf	vwf	NOUN
easat-284	101	20	on	on	ADP
easat-284	101	21	the	the	DET
easat-284	101	22	endothelial	endothelial	ADJ
easat-284	101	23	cell	cell	NOUN
easat-284	101	24	surface	surface	NOUN
easat-284	101	25	,	,	PUNCT
easat-284	101	26	and	and	CCONJ
easat-284	101	27	increase	increase	VERB
easat-284	101	28	the	the	DET
easat-284	101	29	release	release	NOUN
easat-284	101	30	of	of	ADP
easat-284	101	31	vwf	vwf	NOUN
easat-284	101	32	antigen	antigen	VERB
easat-284	101	33	by	by	ADP
easat-284	101	34	endothelial	endothelial	ADJ
easat-284	101	35	cells	cell	NOUN
easat-284	101	36	,	,	PUNCT
easat-284	101	37	resulting	result	VERB
easat-284	101	38	in	in	ADP
easat-284	101	39	persistence	persistence	NOUN
easat-284	101	40	of	of	ADP
easat-284	101	41	vwf	vwf	NOUN
easat-284	101	42	strands	strand	NOUN
easat-284	101	43	and	and	CCONJ
easat-284	101	44	causing	cause	VERB
easat-284	101	45	an	an	DET
easat-284	101	46	increase	increase	NOUN
easat-284	101	47	in	in	ADP
easat-284	101	48	platelet	platelet	NOUN
easat-284	101	49	adhesion	adhesion	NOUN
easat-284	101	50	under	under	ADP
easat-284	101	51	flow	flow	NOUN
easat-284	101	52	conditions	condition	NOUN
easat-284	101	53	[	[	X
easat-284	101	54	36	36	NUM
easat-284	101	55	]	]	PUNCT
easat-284	101	56	.	.	PUNCT
easat-284	102	1	this	this	DET
easat-284	102	2	pathological	pathological	ADJ
easat-284	102	3	chain	chain	NOUN
easat-284	102	4	of	of	ADP
easat-284	102	5	events	event	NOUN
easat-284	102	6	event	event	NOUN
easat-284	102	7	has	have	AUX
easat-284	102	8	been	be	AUX
easat-284	102	9	described	describe	VERB
easat-284	102	10	also	also	ADV
easat-284	102	11	for	for	ADP
easat-284	102	12	multisystemic	multisystemic	ADJ
easat-284	102	13	vasculitis	vasculitis	PROPN
easat-284	102	14	in	in	ADP
easat-284	102	15	kawasaki	kawasaki	PROPN
easat-284	102	16	disease	disease	PROPN
easat-284	102	17	,	,	PUNCT
easat-284	102	18	characterized	characterize	VERB
easat-284	102	19	by	by	ADP
easat-284	102	20	platelet	platelet	NOUN
easat-284	102	21	stimulation	stimulation	NOUN
easat-284	102	22	with	with	ADP
easat-284	102	23	increase	increase	NOUN
easat-284	102	24	in	in	ADP
easat-284	102	25	the	the	DET
easat-284	102	26	shedding	shedding	NOUN
easat-284	102	27	of	of	ADP
easat-284	102	28	pselectin	pselectin	NOUN
easat-284	102	29	,	,	PUNCT
easat-284	102	30	translocati	translocati	NOUN
easat-284	102	31	ng	ng	PROPN
easat-284	102	32	at	at	ADP
easat-284	102	33	the	the	DET
easat-284	102	34	surface	surface	NOUN
easat-284	102	35	and	and	CCONJ
easat-284	102	36	externalized	externalize	VERB
easat-284	102	37	with	with	ADP
easat-284	102	38	subsequent	subsequent	ADJ
easat-284	102	39	hyperactivation	hyperactivation	NOUN
easat-284	102	40	,	,	PUNCT
easat-284	102	41	and	and	CCONJ
easat-284	102	42	the	the	DET
easat-284	102	43	detection	detection	NOUN
easat-284	102	44	of	of	ADP
easat-284	102	45	circulat	circulat	NOUN
easat-284	102	46	ing	ing	ADJ
easat-284	102	47	platelets	platelet	NOUN
easat-284	102	48	-	-	PUNCT
easat-284	102	49	neutrophils	neutrophil	NOUN
easat-284	102	50	aggregates	aggregate	NOUN
easat-284	102	51	.	.	PUNCT
easat-284	103	1	neutrophils	neutrophil	NOUN
easat-284	103	2	recruited	recruit	VERB
easat-284	103	3	by	by	ADP
easat-284	103	4	platelets	platelet	NOUN
easat-284	103	5	pselectin	pselectin	NOUN
easat-284	103	6	and	and	CCONJ
easat-284	103	7	psgl-1	psgl-1	NUM
easat-284	103	8	(	(	PUNCT
easat-284	103	9	vascular	vascular	ADJ
easat-284	103	10	adhesion	adhesion	NOUN
easat-284	103	11	molecules	molecule	NOUN
easat-284	103	12	playing	play	VERB
easat-284	103	13	an	an	DET
easat-284	103	14	important	important	ADJ
easat-284	103	15	role	role	NOUN
easat-284	103	16	in	in	ADP
easat-284	103	17	the	the	DET
easat-284	103	18	inflammatory	inflammatory	ADJ
easat-284	103	19	response	response	NOUN
easat-284	103	20	by	by	ADP
easat-284	103	21	mediating	mediate	VERB
easat-284	103	22	the	the	DET
easat-284	103	23	interaction	interaction	NOUN
easat-284	103	24	of	of	ADP
easat-284	103	25	leucocytes	leucocyte	NOUN
easat-284	103	26	with	with	ADP
easat-284	103	27	stimulated	stimulated	ADJ
easat-284	103	28	endothelium	endothelium	NOUN
easat-284	103	29	and	and	CCONJ
easat-284	103	30	pla	pla	PROPN
easat-284	103	31	telets	telet	NOUN
easat-284	103	32	bound	bind	VERB
easat-284	103	33	in	in	ADP
easat-284	103	34	the	the	DET
easat-284	103	35	vicinity	vicinity	NOUN
easat-284	103	36	of	of	ADP
easat-284	103	37	vascular	vascular	ADJ
easat-284	103	38	injury	injury	NOUN
easat-284	103	39	)	)	PUNCT
easat-284	103	40	contribute	contribute	VERB
easat-284	103	41	,	,	PUNCT
easat-284	103	42	through	through	ADP
easat-284	103	43	toll	toll	NOUN
easat-284	103	44	-	-	PUNCT
easat-284	103	45	like	like	ADJ
easat-284	103	46	receptor	receptor	NOUN
easat-284	103	47	4	4	NUM
easat-284	103	48	,	,	PUNCT
easat-284	103	49	to	to	PART
easat-284	103	50	nets	net	VERB
easat-284	103	51	formation	formation	NOUN
easat-284	103	52	,	,	PUNCT
easat-284	103	53	nets	net	NOUN
easat-284	103	54	cause	cause	VERB
easat-284	103	55	platelet	platelet	NOUN
easat-284	103	56	activation	activation	NOUN
easat-284	103	57	and	and	CCONJ
easat-284	103	58	aggregation	aggregation	NOUN
easat-284	103	59	,	,	PUNCT
easat-284	103	60	thus	thus	ADV
easat-284	103	61	linking	link	VERB
easat-284	103	62	inflammation	inflammation	NOUN
easat-284	103	63	and	and	CCONJ
easat-284	103	64	thrombosis	thrombosis	NOUN
easat-284	103	65	to	to	PART
easat-284	103	66	support	support	VERB
easat-284	103	67	the	the	DET
easat-284	103	68	relevance	relevance	NOUN
easat-284	103	69	of	of	ADP
easat-284	103	70	this	this	DET
easat-284	103	71	mechanism	mechanism	NOUN
easat-284	103	72	in	in	ADP
easat-284	103	73	the	the	DET
easat-284	103	74	pathogenesis	pathogenesis	NOUN
easat-284	103	75	of	of	ADP
easat-284	103	76	covid-19	covid-19	PROPN
easat-284	103	77	.	.	PUNCT
easat-284	104	1	simultaneously	simultaneously	ADV
easat-284	104	2	,	,	PUNCT
easat-284	104	3	serine	serine	ADJ
easat-284	104	4	proteases	protease	NOUN
easat-284	104	5	released	release	VERB
easat-284	104	6	by	by	ADP
easat-284	104	7	neutrophils	neutrophil	NOUN
easat-284	104	8	and	and	CCONJ
easat-284	104	9	present	present	ADJ
easat-284	104	10	in	in	ADP
easat-284	104	11	nets	net	NOUN
easat-284	104	12	cleave	cleave	VERB
easat-284	104	13	coagulation	coagulation	NOUN
easat-284	104	14	inhibitors	inhibitor	NOUN
easat-284	104	15	such	such	ADJ
easat-284	104	16	as	as	ADP
easat-284	104	17	tissue	tissue	NOUN
easat-284	104	18	factor	factor	NOUN
easat-284	104	19	pathway	pathway	NOUN
easat-284	104	20	inhibitor	inhibitor	NOUN
easat-284	104	21	a	a	DET
easat-284	104	22	nd	nd	ADV
easat-284	104	23	antithrombin	antithrombin	NOUN
easat-284	105	1	[	[	X
easat-284	105	2	37	37	NUM
easat-284	105	3	]	]	PUNCT
easat-284	105	4	.	.	PUNCT
easat-284	106	1	on	on	ADP
easat-284	106	2	the	the	DET
easat-284	106	3	damaged	damage	VERB
easat-284	106	4	endothelial	endothelial	ADJ
easat-284	106	5	surface	surface	NOUN
easat-284	106	6	nets	net	NOUN
easat-284	106	7	,	,	PUNCT
easat-284	106	8	ulvwf	ulvwf	NOUN
easat-284	106	9	multimers	multimer	NOUN
easat-284	106	10	,	,	PUNCT
easat-284	106	11	platelets	platelet	NOUN
easat-284	106	12	and	and	CCONJ
easat-284	106	13	activated	activate	VERB
easat-284	106	14	not	not	PART
easat-284	106	15	inhibited	inhibit	VERB
easat-284	106	16	clotting	clotting	NOUN
easat-284	106	17	and	and	CCONJ
easat-284	106	18	complement	complement	NOUN
easat-284	106	19	pathways	pathway	NOUN
easat-284	106	20	initiate	initiate	VERB
easat-284	106	21	thrombogenesis	thrombogenesis	NOUN
easat-284	106	22	within	within	ADP
easat-284	106	23	the	the	DET
easat-284	106	24	microvasculature	microvasculature	NOUN
easat-284	106	25	,	,	PUNCT
easat-284	106	26	leading	lead	VERB
easat-284	106	27	to	to	ADP
easat-284	106	28	microthrombi	microthrombi	NOUN
easat-284	106	29	en	en	ADP
easat-284	106	30	riched	riche	VERB
easat-284	106	31	also	also	ADV
easat-284	106	32	by	by	ADP
easat-284	106	33	leukocytes	leukocyte	NOUN
easat-284	106	34	recruited	recruit	VERB
easat-284	106	35	in	in	ADP
easat-284	106	36	the	the	DET
easat-284	106	37	p	p	NOUN
easat-284	106	38	-	-	PUNCT
easat-284	106	39	selectin	selectin	ADJ
easat-284	106	40	dependent	dependent	ADJ
easat-284	106	41	manner	manner	NOUN
easat-284	107	1	[	[	X
easat-284	107	2	38	38	NUM
easat-284	107	3	]	]	PUNCT
easat-284	107	4	.	.	PUNCT
easat-284	108	1	the	the	DET
easat-284	108	2	microthrombi	microthrombi	NOUN
easat-284	108	3	can	can	AUX
easat-284	108	4	become	become	VERB
easat-284	108	5	sufficiently	sufficiently	ADV
easat-284	108	6	large	large	ADJ
easat-284	108	7	to	to	PART
easat-284	108	8	be	be	AUX
easat-284	108	9	released	release	VERB
easat-284	108	10	from	from	ADP
easat-284	108	11	endothelial	endothelial	ADJ
easat-284	108	12	cells	cell	NOUN
easat-284	108	13	into	into	ADP
easat-284	108	14	the	the	DET
easat-284	108	15	circulation	circulation	NOUN
easat-284	108	16	,	,	PUNCT
easat-284	108	17	resulting	result	VERB
easat-284	108	18	embolism	embolism	NOUN
easat-284	108	19	[	[	X
easat-284	108	20	39].this	39].this	NUM
easat-284	108	21	condition	condition	NOUN
easat-284	108	22	can	can	AUX
easat-284	108	23	be	be	AUX
easat-284	108	24	recalled	recall	VERB
easat-284	108	25	“	"	PUNCT
easat-284	108	26	ttp	ttp	NOUN
easat-284	108	27	-	-	PUNCT
easat-284	108	28	like	like	ADJ
easat-284	108	29	syndrome	syndrome	NOUN
easat-284	108	30	”	"	PUNCT
easat-284	109	1	[	[	X
easat-284	109	2	40	40	NUM
easat-284	109	3	]	]	PUNCT
easat-284	109	4	.	.	PUNCT
easat-284	110	1	blood	blood	NOUN
easat-284	110	2	circulation	circulation	NOUN
easat-284	110	3	action	action	NOUN
easat-284	110	4	and	and	CCONJ
easat-284	110	5	mechanical	mechanical	ADJ
easat-284	110	6	stress	stress	NOUN
easat-284	110	7	(	(	PUNCT
easat-284	110	8	like	like	ADP
easat-284	110	9	forced	force	VERB
easat-284	110	10	ventilation	ventilation	NOUN
easat-284	110	11	)	)	PUNCT
easat-284	110	12	may	may	AUX
easat-284	110	13	be	be	AUX
easat-284	110	14	sufficient	sufficient	ADJ
easat-284	110	15	to	to	PART
easat-284	110	16	physically	physically	ADV
easat-284	110	17	disrupt	disrupt	VERB
easat-284	110	18	the	the	DET
easat-284	110	19	fragile	fragile	ADJ
easat-284	110	20	structure	structure	NOUN
easat-284	110	21	of	of	ADP
easat-284	110	22	nets	net	NOUN
easat-284	110	23	in	in	ADP
easat-284	110	24	the	the	DET
easat-284	110	25	bloodstream	bloodstream	NOUN
easat-284	110	26	,	,	PUNCT
easat-284	110	27	releasing	release	VERB
easat-284	110	28	net	net	ADJ
easat-284	110	29	fragments	fragment	NOUN
easat-284	110	30	.	.	PUNCT
easat-284	111	1	mechanically	mechanically	ADV
easat-284	111	2	disrupted	disrupt	VERB
easat-284	111	3	nets	net	NOUN
easat-284	111	4	augment	augment	VERB
easat-284	111	5	netosis	netosis	NOUN
easat-284	111	6	and	and	CCONJ
easat-284	111	7	netosis	netosis	NOUN
easat-284	111	8	propagates	propagate	VERB
easat-284	111	9	inflammatory	inflammatory	ADJ
easat-284	111	10	response	response	NOUN
easat-284	111	11	.	.	PUNCT
easat-284	112	1	tlr	tlr	PROPN
easat-284	112	2	inhibitors	inhibitor	NOUN
easat-284	112	3	may	may	AUX
easat-284	112	4	reduce	reduce	VERB
easat-284	112	5	inflammation	inflammation	NOUN
easat-284	112	6	,	,	PUNCT
easat-284	112	7	specifically	specifically	ADV
easat-284	112	8	by	by	ADP
easat-284	112	9	preventing	prevent	VERB
easat-284	112	10	net	net	NOUN
easat-284	112	11	-	-	PUNCT
easat-284	112	12	induced	induce	VERB
easat-284	112	13	netosis	netosis	NOUN
easat-284	112	14	.	.	PUNCT
easat-284	113	1	intravascular	intravascular	ADJ
easat-284	113	2	netosis	netosis	NOUN
easat-284	113	3	is	be	AUX
easat-284	113	4	thus	thus	ADV
easat-284	113	5	responsible	responsible	ADJ
easat-284	113	6	for	for	ADP
easat-284	113	7	initiation	initiation	NOUN
easat-284	113	8	,	,	PUNCT
easat-284	113	9	dissemination	dissemination	NOUN
easat-284	113	10	and	and	CCONJ
easat-284	113	11	local	local	ADJ
easat-284	113	12	accretion	accretion	NOUN
easat-284	113	13	of	of	ADP
easat-284	113	14	thrombotic	thrombotic	ADJ
easat-284	113	15	events	event	NOUN
easat-284	113	16	in	in	ADP
easat-284	113	17	arteries	artery	NOUN
easat-284	113	18	,	,	PUNCT
easat-284	113	19	veins	vein	NOUN
easat-284	113	20	and	and	CCONJ
easat-284	113	21	in	in	ADP
easat-284	113	22	the	the	DET
easat-284	113	23	microvasculature	microvasculature	NOUN
easat-284	113	24	,	,	PUNCT
easat-284	113	25	with	with	ADP
easat-284	113	26	end	end	NOUN
easat-284	113	27	-organ	-organ	NOUN
easat-284	113	28	damage	damage	NOUN
easat-284	113	29	in	in	ADP
easat-284	113	30	lungs	lung	NOUN
easat-284	113	31	,	,	PUNCT
easat-284	113	32	heart	heart	NOUN
easat-284	113	33	,	,	PUNCT
easat-284	113	34	kidneys	kidney	NOUN
easat-284	113	35	and	and	CCONJ
easat-284	113	36	other	other	ADJ
easat-284	113	37	organs	organ	NOUN
easat-284	113	38	[	[	X
easat-284	113	39	41	41	NUM
easat-284	113	40	]	]	PUNCT
easat-284	113	41	.	.	PUNCT
easat-284	114	1	through	through	ADP
easat-284	114	2	endothelial	endothelial	ADJ
easat-284	114	3	lesions	lesion	NOUN
easat-284	114	4	and	and	CCONJ
easat-284	114	5	nets	net	NOUN
easat-284	114	6	,	,	PUNCT
easat-284	114	7	sars	sar	NOUN
easat-284	114	8	-	-	PUNCT
easat-284	114	9	cov-2	cov-2	PART
easat-284	114	10	virus	virus	NOUN
easat-284	114	11	activates	activate	VERB
easat-284	114	12	its	its	PRON
easat-284	114	13	viremic	viremic	ADJ
easat-284	114	14	phase	phase	NOUN
easat-284	114	15	and	and	CCONJ
easat-284	114	16	in	in	ADP
easat-284	114	17	each	each	DET
easat-284	114	18	interested	interested	ADJ
easat-284	114	19	organ	organ	NOUN
easat-284	114	20	(	(	PUNCT
easat-284	114	21	figure	figure	NOUN
easat-284	114	22	1	1	NUM
easat-284	114	23	)	)	PUNCT
easat-284	114	24	follows	follow	VERB
easat-284	114	25	the	the	DET
easat-284	114	26	same	same	ADJ
easat-284	114	27	cellular	cellular	ADJ
easat-284	114	28	entry	entry	NOUN
easat-284	114	29	strategy	strategy	NOUN
easat-284	114	30	and	and	CCONJ
easat-284	114	31	catastrophic	catastrophic	ADJ
easat-284	114	32	microvascular	microvascular	ADJ
easat-284	114	33	injury	injury	NOUN
easat-284	114	34	syndrome	syndrome	NOUN
easat-284	114	35	,	,	PUNCT
easat-284	114	36	causing	cause	VERB
easat-284	114	37	final	final	ADJ
easat-284	114	38	mof	mof	ADJ
easat-284	114	39	.	.	PUNCT
easat-284	114	40	proteolytic	proteolytic	ADJ
easat-284	114	41	cascades	cascade	NOUN
easat-284	114	42	balance	balance	NOUN
easat-284	114	43	between	between	ADP
easat-284	114	44	activators	activator	NOUN
easat-284	114	45	and	and	CCONJ
easat-284	114	46	inhibitors	inhibitor	NOUN
easat-284	114	47	is	be	AUX
easat-284	114	48	unbalanced	unbalanced	ADJ
easat-284	114	49	in	in	ADP
easat-284	114	50	covid	covid	PROPN
easat-284	114	51	-19	-19	PROPN
easat-284	114	52	:	:	PUNCT
easat-284	114	53	if	if	SCONJ
easat-284	114	54	nets	net	NOUN
easat-284	114	55	induce	induce	VERB
easat-284	114	56	hypercoagulability	hypercoagulability	NOUN
easat-284	114	57	,	,	PUNCT
easat-284	114	58	the	the	DET
easat-284	114	59	significant	significant	ADJ
easat-284	114	60	increase	increase	NOUN
easat-284	114	61	in	in	ADP
easat-284	114	62	neutrophil	neutrophil	ADJ
easat-284	114	63	numbers	number	NOUN
easat-284	114	64	and	and	CCONJ
easat-284	114	65	the	the	DET
easat-284	114	66	released	release	VERB
easat-284	114	67	proteolytic	proteolytic	ADJ
easat-284	114	68	enzymes	enzyme	NOUN
easat-284	114	69	(	(	PUNCT
easat-284	114	70	mainly	mainly	ADV
easat-284	114	71	elastase	elastase	NOUN
easat-284	114	72	)	)	PUNCT
easat-284	114	73	contribute	contribute	VERB
easat-284	114	74	to	to	ADP
easat-284	114	75	a	a	DET
easat-284	114	76	consumption	consumption	NOUN
easat-284	114	77	of	of	ADP
easat-284	114	78	proteases	protease	NOUN
easat-284	114	79	inhibitors	inhibitor	NOUN
easat-284	114	80	,	,	PUNCT
easat-284	114	81	with	with	ADP
easat-284	114	82	an	an	DET
easat-284	114	83	umbalance	umbalance	NOUN
easat-284	114	84	of	of	ADP
easat-284	114	85	physiologic	physiologic	ADJ
easat-284	114	86	conditions	condition	NOUN
easat-284	114	87	and	and	CCONJ
easat-284	114	88	instauration	instauration	NOUN
easat-284	114	89	of	of	ADP
easat-284	114	90	the	the	DET
easat-284	114	91	“	"	PUNCT
easat-284	114	92	proteolytic	proteolytic	ADJ
easat-284	114	93	storm	storm	NOUN
easat-284	114	94	”	"	PUNCT
easat-284	115	1	[	[	X
easat-284	115	2	42	42	NUM
easat-284	115	3	]	]	PUNCT
easat-284	115	4	(	(	PUNCT
easat-284	115	5	figure	figure	NOUN
easat-284	115	6	4	4	NUM
easat-284	115	7	)	)	PUNCT
easat-284	115	8	.	.	PUNCT
easat-284	116	1	figure	figure	VERB
easat-284	116	2	4	4	NUM
easat-284	116	3	.	.	PUNCT
easat-284	117	1	covid-19	covid-19	PROPN
easat-284	117	2	clinical	clinical	ADJ
easat-284	117	3	evolution	evolution	NOUN
easat-284	117	4	.	.	PUNCT
easat-284	118	1	neutrophils	neutrophil	NOUN
easat-284	118	2	are	be	AUX
easat-284	118	3	actively	actively	ADV
easat-284	118	4	recruited	recruit	VERB
easat-284	118	5	by	by	ADP
easat-284	118	6	cytokines	cytokine	NOUN
easat-284	118	7	and	and	CCONJ
easat-284	118	8	platelets	platelet	NOUN
easat-284	118	9	,	,	PUNCT
easat-284	118	10	released	release	VERB
easat-284	118	11	high	high	ADJ
easat-284	118	12	levels	level	NOUN
easat-284	118	13	of	of	ADP
easat-284	118	14	serine	serine	NOUN
easat-284	118	15	proteases	protease	NOUN
easat-284	118	16	imbalance	imbalance	NOUN
easat-284	119	1	mainly	mainly	ADV
easat-284	119	2	coagulation	coagulation	NOUN
easat-284	119	3	/	/	SYM
easat-284	119	4	complement	complement	NOUN
easat-284	119	5	/	/	SYM
easat-284	119	6	fibrinolytic	fibrinolytic	ADJ
easat-284	119	7	cascades	cascade	NOUN
easat-284	119	8	inducing	induce	VERB
easat-284	119	9	a	a	DET
easat-284	119	10	severe	severe	ADJ
easat-284	119	11	“	"	PUNCT
easat-284	119	12	proteolytic	proteolytic	ADJ
easat-284	119	13	storm	storm	NOUN
easat-284	119	14	”	"	PUNCT
easat-284	119	15	with	with	ADP
easat-284	119	16	hypercoagulability	hypercoagulability	NOUN
easat-284	119	17	(	(	PUNCT
easat-284	119	18	micro	micro	ADJ
easat-284	119	19	/	/	ADJ
easat-284	119	20	macroangiopathic	macroangiopathic	ADJ
easat-284	119	21	endotheliopathy	endotheliopathy	NOUN
easat-284	119	22	)	)	PUNCT
easat-284	119	23	,	,	PUNCT
easat-284	119	24	endothelial	endothelial	ADJ
easat-284	119	25	lesions	lesion	NOUN
easat-284	119	26	and	and	CCONJ
easat-284	119	27	inflammation	inflammation	NOUN
easat-284	119	28	,	,	PUNCT
easat-284	119	29	nets	net	VERB
easat-284	119	30	formation	formation	NOUN
easat-284	119	31	and	and	CCONJ
easat-284	119	32	bloodstream	bloodstream	NOUN
easat-284	119	33	diffusion	diffusion	NOUN
easat-284	119	34	through	through	ADP
easat-284	119	35	mechanical	mechanical	ADJ
easat-284	119	36	fragmentation	fragmentation	NOUN
easat-284	119	37	.	.	PUNCT
easat-284	120	1	through	through	ADP
easat-284	120	2	endothelial	endothelial	ADJ
easat-284	120	3	lesions	lesion	NOUN
easat-284	120	4	,	,	PUNCT
easat-284	120	5	sars	sar	NOUN
easat-284	120	6	-	-	PUNCT
easat-284	120	7	cov-2	cov-2	NUM
easat-284	120	8	can	can	AUX
easat-284	120	9	disseminate	disseminate	VERB
easat-284	120	10	to	to	ADP
easat-284	120	11	organs	organ	NOUN
easat-284	120	12	presenting	present	VERB
easat-284	120	13	dual	dual	ADJ
easat-284	120	14	ace2	ace2	NOUN
easat-284	120	15	receptor	receptor	NOUN
easat-284	120	16	and	and	CCONJ
easat-284	120	17	tmprss2	tmprss2	PROPN
easat-284	120	18	.	.	PUNCT
easat-284	121	1	70	70	NUM
easat-284	121	2	edelweiss	edelweiss	PROPN
easat-284	121	3	applied	apply	VERB
easat-284	121	4	science	science	NOUN
easat-284	121	5	and	and	CCONJ
easat-284	121	6	technology	technology	NOUN
easat-284	121	7	issn	issn	PROPN
easat-284	121	8	:	:	PUNCT
easat-284	121	9	2576	2576	NUM
easat-284	121	10	-	-	SYM
easat-284	121	11	8484	8484	NUM
easat-284	121	12	vol	vol	NOUN
easat-284	121	13	.	.	PROPN
easat-284	122	1	4	4	NUM
easat-284	122	2	,	,	PUNCT
easat-284	122	3	no	no	INTJ
easat-284	122	4	.	.	NOUN
easat-284	122	5	1	1	NUM
easat-284	122	6	:	:	SYM
easat-284	122	7	67	67	NUM
easat-284	122	8	-	-	SYM
easat-284	122	9	73	73	NUM
easat-284	122	10	,	,	PUNCT
easat-284	122	11	2020	2020	NUM
easat-284	122	12	doi	doi	NOUN
easat-284	122	13	:	:	PUNCT
easat-284	122	14	10.33805/2576	10.33805/2576	NUM
easat-284	122	15	-	-	SYM
easat-284	122	16	8484.184	8484.184	NUM
easat-284	122	17	©	©	PROPN
easat-284	122	18	2020	2020	NUM
easat-284	122	19	by	by	ADP
easat-284	122	20	the	the	DET
easat-284	122	21	author	author	NOUN
easat-284	122	22	the	the	DET
easat-284	122	23	activators	activator	NOUN
easat-284	122	24	/	/	SYM
easat-284	122	25	inhibitors	inhibitor	NOUN
easat-284	122	26	balance	balance	NOUN
easat-284	122	27	in	in	ADP
easat-284	122	28	proteolytic	proteolytic	ADJ
easat-284	122	29	cascades	cascade	NOUN
easat-284	122	30	is	be	AUX
easat-284	122	31	essential	essential	ADJ
easat-284	122	32	for	for	ADP
easat-284	122	33	homeostasis	homeostasis	NOUN
easat-284	122	34	and	and	CCONJ
easat-284	122	35	,	,	PUNCT
easat-284	122	36	due	due	ADP
easat-284	122	37	to	to	ADP
easat-284	122	38	this	this	PRON
easat-284	122	39	,	,	PUNCT
easat-284	122	40	in	in	ADP
easat-284	122	41	normality	normality	NOUN
easat-284	122	42	the	the	DET
easat-284	122	43	inh	inh	PROPN
easat-284	122	44	ibitor	ibitor	NOUN
easat-284	122	45	plate	plate	NOUN
easat-284	122	46	is	be	AUX
easat-284	122	47	largely	largely	ADV
easat-284	122	48	superior	superior	ADJ
easat-284	122	49	to	to	PART
easat-284	122	50	activator	activator	NOUN
easat-284	123	1	one	one	NUM
easat-284	123	2	[	[	X
easat-284	123	3	43	43	NUM
easat-284	123	4	-	-	SYM
easat-284	123	5	45	45	NUM
easat-284	123	6	]	]	PUNCT
easat-284	123	7	.	.	PUNCT
easat-284	124	1	the	the	DET
easat-284	124	2	innate	innate	ADJ
easat-284	124	3	serine	serine	NOUN
easat-284	124	4	protease	protease	NOUN
easat-284	124	5	system	system	NOUN
easat-284	124	6	has	have	VERB
easat-284	124	7	four	four	NUM
easat-284	124	8	major	major	ADJ
easat-284	124	9	columns	column	NOUN
easat-284	124	10	,	,	PUNCT
easat-284	124	11	coagulation	coagulation	NOUN
easat-284	124	12	,	,	PUNCT
easat-284	124	13	fibrinolysis	fibrinolysis	NOUN
easat-284	124	14	,	,	PUNCT
easat-284	124	15	kallikrein	kallikrein	ADJ
easat-284	124	16	and	and	CCONJ
easat-284	124	17	complement	complement	VERB
easat-284	124	18	[	[	X
easat-284	124	19	44	44	NUM
easat-284	124	20	]	]	PUNCT
easat-284	124	21	.	.	PUNCT
easat-284	125	1	these	these	DET
easat-284	125	2	systems	system	NOUN
easat-284	125	3	are	be	AUX
easat-284	125	4	strictly	strictly	ADV
easat-284	125	5	correlated	correlate	VERB
easat-284	125	6	,	,	PUNCT
easat-284	125	7	interconnected	interconnected	ADJ
easat-284	125	8	and	and	CCONJ
easat-284	125	9	their	their	PRON
easat-284	125	10	physiological	physiological	ADJ
easat-284	125	11	mantainance	mantainance	NOUN
easat-284	125	12	is	be	AUX
easat-284	125	13	the	the	DET
easat-284	125	14	result	result	NOUN
easat-284	125	15	of	of	ADP
easat-284	125	16	a	a	DET
easat-284	125	17	rigorous	rigorous	ADJ
easat-284	125	18	balance	balance	NOUN
easat-284	125	19	.	.	PUNCT
easat-284	126	1	complement	complement	NOUN
easat-284	126	2	directly	directly	ADV
easat-284	126	3	enhances	enhance	VERB
easat-284	126	4	coagulation	coagulation	NOUN
easat-284	126	5	and	and	CCONJ
easat-284	126	6	,	,	PUNCT
easat-284	126	7	in	in	ADP
easat-284	126	8	addition	addition	NOUN
easat-284	126	9	,	,	PUNCT
easat-284	126	10	inhibits	inhibit	VERB
easat-284	126	11	anticoagulant	anticoagulant	ADJ
easat-284	126	12	factors	factor	NOUN
easat-284	126	13	,	,	PUNCT
easat-284	126	14	while	while	SCONJ
easat-284	126	15	certain	certain	ADJ
easat-284	126	16	coagulation	coagulation	NOUN
easat-284	126	17	enzymes	enzyme	NOUN
easat-284	126	18	activate	activate	VERB
easat-284	126	19	complement	complement	NOUN
easat-284	126	20	components	component	NOUN
easat-284	126	21	.	.	PUNCT
easat-284	127	1	the	the	DET
easat-284	127	2	interplay	interplay	NOUN
easat-284	127	3	between	between	ADP
easat-284	127	4	complement	complement	NOUN
easat-284	127	5	and	and	CCONJ
easat-284	127	6	coagulation	coagulation	NOUN
easat-284	127	7	is	be	AUX
easat-284	127	8	crucial	crucial	ADJ
easat-284	127	9	to	to	PART
easat-284	127	10	understand	understand	VERB
easat-284	127	11	the	the	DET
easat-284	127	12	clinical	clinical	ADJ
easat-284	127	13	implications	implication	NOUN
easat-284	127	14	in	in	ADP
easat-284	127	15	covid-19	covid-19	PROPN
easat-284	127	16	,	,	PUNCT
easat-284	127	17	in	in	ADP
easat-284	127	18	which	which	PRON
easat-284	127	19	complement	complement	NOUN
easat-284	127	20	-	-	PUNCT
easat-284	127	21	coagulation	coagulation	NOUN
easat-284	127	22	interactions	interaction	NOUN
easat-284	127	23	contribute	contribute	VERB
easat-284	127	24	to	to	ADP
easat-284	127	25	the	the	DET
easat-284	127	26	development	development	NOUN
easat-284	127	27	of	of	ADP
easat-284	127	28	life	life	NOUN
easat-284	127	29	-	-	PUNCT
easat-284	127	30	threatening	threaten	VERB
easat-284	127	31	complications	complication	NOUN
easat-284	127	32	[	[	X
easat-284	127	33	23	23	NUM
easat-284	127	34	]	]	PUNCT
easat-284	127	35	.	.	PUNCT
easat-284	128	1	the	the	DET
easat-284	128	2	contact	contact	NOUN
easat-284	128	3	system	system	NOUN
easat-284	128	4	,	,	PUNCT
easat-284	128	5	also	also	ADV
easat-284	128	6	named	name	VERB
easat-284	128	7	as	as	ADP
easat-284	128	8	plasma	plasma	NOUN
easat-284	128	9	kallikrein	kallikrein	ADJ
easat-284	128	10	-	-	PUNCT
easat-284	128	11	kinin	kinin	ADJ
easat-284	128	12	system	system	NOUN
easat-284	128	13	,	,	PUNCT
easat-284	128	14	consists	consist	VERB
easat-284	128	15	of	of	ADP
easat-284	128	16	three	three	NUM
easat-284	128	17	serine	serine	NOUN
easat-284	128	18	proteinases	proteinase	NOUN
easat-284	128	19	:	:	PUNCT
easat-284	128	20	coagulation	coagulation	NOUN
easat-284	128	21	factors	factor	NOUN
easat-284	128	22	xii	xii	NOUN
easat-284	128	23	and	and	CCONJ
easat-284	128	24	xi	xi	NOUN
easat-284	128	25	,	,	PUNCT
easat-284	128	26	plasma	plasma	NOUN
easat-284	128	27	prekallikrein	prekallikrein	NOUN
easat-284	128	28	and	and	CCONJ
easat-284	128	29	high	high	ADJ
easat-284	128	30	molecular	molecular	ADJ
easat-284	128	31	weight	weight	NOUN
easat-284	128	32	kininogen	kininogen	NOUN
easat-284	128	33	.	.	PUNCT
easat-284	129	1	once	once	ADV
easat-284	129	2	activated	activate	VERB
easat-284	129	3	by	by	ADP
easat-284	129	4	nets	net	NOUN
easat-284	129	5	,	,	PUNCT
easat-284	129	6	this	this	DET
easat-284	129	7	system	system	NOUN
easat-284	129	8	is	be	AUX
easat-284	129	9	prothrombotic	prothrombotic	ADJ
easat-284	129	10	by	by	ADP
easat-284	129	11	activating	activate	VERB
easat-284	129	12	intrinsic	intrinsic	ADJ
easat-284	129	13	pathway	pathway	NOUN
easat-284	129	14	and	and	CCONJ
easat-284	129	15	proinflammatory	proinflammatory	NOUN
easat-284	129	16	by	by	ADP
easat-284	129	17	producing	produce	VERB
easat-284	129	18	bioactive	bioactive	NOUN
easat-284	129	19	peptide	peptide	NOUN
easat-284	129	20	bradykinin	bradykinin	PROPN
easat-284	129	21	.	.	PUNCT
easat-284	130	1	extrinsic	extrinsic	ADJ
easat-284	130	2	and	and	CCONJ
easat-284	130	3	intrinsic	intrinsic	ADJ
easat-284	130	4	pathwa	pathwa	PROPN
easat-284	130	5	y	y	PROPN
easat-284	130	6	of	of	ADP
easat-284	130	7	blood	blood	NOUN
easat-284	130	8	coagulation	coagulation	NOUN
easat-284	130	9	induces	induce	VERB
easat-284	130	10	simultaneous	simultaneous	ADJ
easat-284	130	11	activation	activation	NOUN
easat-284	130	12	of	of	ADP
easat-284	130	13	the	the	DET
easat-284	130	14	complement	complement	NOUN
easat-284	130	15	and	and	CCONJ
easat-284	130	16	fib	fib	VERB
easat-284	130	17	rinolysis	rinolysis	NOUN
easat-284	130	18	cascades	cascade	NOUN
easat-284	130	19	,	,	PUNCT
easat-284	130	20	with	with	ADP
easat-284	130	21	an	an	DET
easat-284	130	22	extensive	extensive	ADJ
easat-284	130	23	cross	cross	NOUN
easat-284	130	24	talk	talk	NOUN
easat-284	130	25	mutually	mutually	ADV
easat-284	130	26	fine	fine	ADV
easat-284	130	27	-	-	PUNCT
easat-284	130	28	tuning	tune	VERB
easat-284	130	29	their	their	PRON
easat-284	130	30	activation	activation	NOUN
easat-284	130	31	status	status	NOUN
easat-284	130	32	[	[	X
easat-284	130	33	46	46	NUM
easat-284	130	34	]	]	PUNCT
easat-284	130	35	.	.	PUNCT
easat-284	131	1	main	main	ADJ
easat-284	131	2	family	family	NOUN
easat-284	131	3	of	of	ADP
easat-284	131	4	the	the	DET
easat-284	131	5	serine	serine	NOUN
easat-284	131	6	protease	protease	NOUN
easat-284	131	7	inhibitors	inhibitor	NOUN
easat-284	131	8	(	(	PUNCT
easat-284	131	9	serpins	serpin	NOUN
easat-284	131	10	)	)	PUNCT
easat-284	131	11	is	be	AUX
easat-284	131	12	formed	form	VERB
easat-284	131	13	by	by	ADP
easat-284	131	14	serpina1	serpina1	X
easat-284	131	15	(	(	PUNCT
easat-284	131	16	ɑ1	ɑ1	NOUN
easat-284	131	17	-	-	PUNCT
easat-284	131	18	antitrypsin	antitrypsin	NOUN
easat-284	131	19	)	)	PUNCT
easat-284	131	20	protecting	protect	VERB
easat-284	131	21	lung	lung	NOUN
easat-284	131	22	tissue	tissue	NOUN
easat-284	131	23	from	from	ADP
easat-284	131	24	neutrophil	neutrophil	ADJ
easat-284	131	25	elastase	elastase	NOUN
easat-284	131	26	,	,	PUNCT
easat-284	131	27	serpina5	serpina5	NOUN
easat-284	131	28	(	(	PUNCT
easat-284	131	29	protein	protein	NOUN
easat-284	131	30	c	c	NOUN
easat-284	131	31	inhibitor	inhibitor	NOUN
easat-284	131	32	)	)	PUNCT
easat-284	131	33	,	,	PUNCT
easat-284	131	34	serpinc1	serpinc1	NOUN
easat-284	131	35	(	(	PUNCT
easat-284	131	36	also	also	ADV
easat-284	131	37	known	know	VERB
easat-284	131	38	as	as	ADP
easat-284	131	39	antithrombin	antithrombin	NOUN
easat-284	131	40	)	)	PUNCT
easat-284	131	41	controls	control	VERB
easat-284	131	42	coagulation	coagulation	NOUN
easat-284	131	43	proteases	protease	NOUN
easat-284	131	44	,	,	PUNCT
easat-284	131	45	serpind	serpind	NOUN
easat-284	131	46	(	(	PUNCT
easat-284	131	47	heparin	heparin	ADJ
easat-284	131	48	cofactorii	cofactorii	NOUN
easat-284	131	49	)	)	PUNCT
easat-284	131	50	,	,	PUNCT
easat-284	131	51	serpine1	serpine1	X
easat-284	131	52	(	(	PUNCT
easat-284	131	53	plaminogen	plaminogen	NOUN
easat-284	131	54	activator	activator	NOUN
easat-284	131	55	inhibitor	inhibitor	NOUN
easat-284	131	56	1	1	NUM
easat-284	131	57	)	)	PUNCT
easat-284	131	58	,	,	PUNCT
easat-284	131	59	serping1	serping1	X
easat-284	132	1	(	(	PUNCT
easat-284	132	2	also	also	ADV
easat-284	132	3	known	know	VERB
easat-284	132	4	as	as	ADP
easat-284	132	5	plasma	plasma	NOUN
easat-284	132	6	c1	c1	PROPN
easat-284	132	7	inhibitor	inhibitor	NOUN
easat-284	132	8	)	)	PUNCT
easat-284	132	9	regulates	regulate	VERB
easat-284	132	10	complement	complement	NOUN
easat-284	132	11	,	,	PUNCT
easat-284	132	12	callicrein	callicrein	NOUN
easat-284	132	13	and	and	CCONJ
easat-284	132	14	contact	contact	NOUN
easat-284	132	15	phase	phase	NOUN
easat-284	132	16	activation	activation	NOUN
easat-284	132	17	and	and	CCONJ
easat-284	132	18	serpinf2	serpinf2	NOUN
easat-284	132	19	(	(	PUNCT
easat-284	132	20	also	also	ADV
easat-284	132	21	known	know	VERB
easat-284	132	22	as	as	ADP
easat-284	132	23	ɑ-2antiplasmin	ɑ-2antiplasmin	NOUN
easat-284	132	24	)	)	PUNCT
easat-284	132	25	inhibits	inhibit	VERB
easat-284	132	26	plasmin	plasmin	ADJ
easat-284	132	27	and	and	CCONJ
easat-284	132	28	regulates	regulate	VERB
easat-284	132	29	fibrinolysis	fibrinolysis	NOUN
easat-284	132	30	.	.	PUNCT
easat-284	133	1	complement	complement	NOUN
easat-284	133	2	activation	activation	NOUN
easat-284	133	3	is	be	AUX
easat-284	133	4	inhibited	inhibit	VERB
easat-284	133	5	also	also	ADV
easat-284	133	6	by	by	ADP
easat-284	133	7	decay	decay	NOUN
easat-284	133	8	-accelerating	-accelerate	VERB
easat-284	133	9	factor	factor	NOUN
easat-284	133	10	(	(	PUNCT
easat-284	133	11	daf	daf	NOUN
easat-284	133	12	)	)	PUNCT
easat-284	133	13	and	and	CCONJ
easat-284	133	14	factor	factor	NOUN
easat-284	133	15	h	h	NOUN
easat-284	133	16	(	(	PUNCT
easat-284	133	17	alternative	alternative	ADJ
easat-284	133	18	pathway	pathway	NOUN
easat-284	133	19	)	)	PUNCT
easat-284	133	20	.	.	PUNCT
easat-284	134	1	alpha	alpha	NOUN
easat-284	134	2	2	2	NUM
easat-284	134	3	macroglobulin	macroglobulin	PROPN
easat-284	134	4	acts	act	VERB
easat-284	134	5	as	as	ADP
easat-284	134	6	an	an	DET
easat-284	134	7	antiprotease	antiprotease	NOUN
easat-284	134	8	for	for	ADP
easat-284	134	9	a	a	DET
easat-284	134	10	variety	variety	NOUN
easat-284	134	11	of	of	ADP
easat-284	134	12	proteases	protease	NOUN
easat-284	134	13	like	like	ADP
easat-284	134	14	plasmin	plasmin	NOUN
easat-284	134	15	,	,	PUNCT
easat-284	134	16	kallikrein	kallikrein	ADJ
easat-284	134	17	and	and	CCONJ
easat-284	134	18	thrombin	thrombin	NOUN
easat-284	134	19	.	.	PUNCT
easat-284	135	1	a	a	DET
easat-284	135	2	delicate	delicate	ADJ
easat-284	135	3	balance	balance	NOUN
easat-284	135	4	between	between	ADP
easat-284	135	5	serine	serine	NOUN
easat-284	135	6	proteases	protease	NOUN
easat-284	135	7	and	and	CCONJ
easat-284	135	8	their	their	PRON
easat-284	135	9	serpin	serpin	NOUN
easat-284	135	10	inhibitors	inhibitor	NOUN
easat-284	135	11	is	be	AUX
easat-284	135	12	crucial	crucial	ADJ
easat-284	135	13	for	for	ADP
easat-284	135	14	normal	normal	ADJ
easat-284	135	15	functioning	functioning	NOUN
easat-284	135	16	of	of	ADP
easat-284	135	17	biological	biological	ADJ
easat-284	135	18	pathways	pathway	NOUN
easat-284	136	1	[	[	X
easat-284	136	2	43	43	NUM
easat-284	136	3	]	]	PUNCT
easat-284	136	4	.	.	PUNCT
easat-284	137	1	proteases	protease	NOUN
easat-284	137	2	/	/	SYM
easat-284	137	3	antiproteases	antiprotease	NOUN
easat-284	137	4	balance	balance	NOUN
easat-284	137	5	is	be	AUX
easat-284	137	6	present	present	ADJ
easat-284	137	7	also	also	ADV
easat-284	137	8	at	at	ADP
easat-284	137	9	the	the	DET
easat-284	137	10	endothelial	endothelial	ADJ
easat-284	137	11	surface	surface	NOUN
easat-284	137	12	,	,	PUNCT
easat-284	137	13	where	where	SCONJ
easat-284	137	14	thrombomodulin	thrombomodulin	PROPN
easat-284	137	15	,	,	PUNCT
easat-284	137	16	forming	form	VERB
easat-284	137	17	complexes	complex	NOUN
easat-284	137	18	with	with	ADP
easat-284	137	19	thrombin	thrombin	NOUN
easat-284	137	20	,	,	PUNCT
easat-284	137	21	induces	induce	VERB
easat-284	137	22	protein	protein	NOUN
easat-284	137	23	c	c	NOUN
easat-284	137	24	activation	activation	NOUN
easat-284	137	25	to	to	PART
easat-284	137	26	suppress	suppress	VERB
easat-284	137	27	blood	blood	NOUN
easat-284	137	28	coagulation	coagulation	NOUN
easat-284	137	29	,	,	PUNCT
easat-284	137	30	while	while	SCONJ
easat-284	137	31	tnf	tnf	PROPN
easat-284	137	32	-	-	PUNCT
easat-284	137	33	alpha	alpha	NOUN
easat-284	137	34	and	and	CCONJ
easat-284	137	35	il-1beta	il-1beta	NOUN
easat-284	137	36	,	,	PUNCT
easat-284	137	37	inducing	induce	VERB
easat-284	137	38	tf	tf	X
easat-284	137	39	and	and	CCONJ
easat-284	137	40	pai-1	pai-1	NUM
easat-284	137	41	,	,	PUNCT
easat-284	137	42	down	down	ADV
easat-284	137	43	-	-	PUNCT
easat-284	137	44	regulate	regulate	VERB
easat-284	137	45	the	the	DET
easat-284	137	46	expression	expression	NOUN
easat-284	137	47	of	of	ADP
easat-284	137	48	thrombomodulin	thrombomodulin	PROPN
easat-284	137	49	.	.	PUNCT
easat-284	138	1	procoagulant	procoagulant	PROPN
easat-284	138	2	tf	tf	PROPN
easat-284	138	3	upregulation	upregulation	NOUN
easat-284	138	4	with	with	ADP
easat-284	138	5	downregulation	downregulation	NOUN
easat-284	138	6	of	of	ADP
easat-284	138	7	the	the	DET
easat-284	138	8	anticoagulant	anticoagulant	ADJ
easat-284	138	9	tm	tm	NOUN
easat-284	138	10	/	/	SYM
easat-284	138	11	protein	protein	NOUN
easat-284	138	12	c	c	NOUN
easat-284	138	13	system	system	NOUN
easat-284	138	14	converts	convert	VERB
easat-284	138	15	the	the	DET
easat-284	138	16	normal	normal	ADJ
easat-284	138	17	anticoagulant	anticoagulant	ADJ
easat-284	138	18	endothelium	endothelium	NOUN
easat-284	138	19	into	into	ADP
easat-284	138	20	a	a	DET
easat-284	138	21	prothrombotic	prothrombotic	ADJ
easat-284	138	22	endothelium	endothelium	NOUN
easat-284	138	23	.	.	PUNCT
easat-284	139	1	lastly	lastly	ADV
easat-284	139	2	,	,	PUNCT
easat-284	139	3	nets	net	NOUN
easat-284	139	4	triggered	trigger	VERB
easat-284	139	5	significant	significant	ADJ
easat-284	139	6	platelet	platelet	NOUN
easat-284	139	7	aggregation	aggregation	NOUN
easat-284	139	8	.	.	PUNCT
easat-284	140	1	a	a	DET
easat-284	140	2	proteases	protease	NOUN
easat-284	140	3	/	/	SYM
easat-284	140	4	antiproteases	antiprotease	NOUN
easat-284	140	5	balance	balance	NOUN
easat-284	140	6	is	be	AUX
easat-284	140	7	present	present	ADJ
easat-284	140	8	also	also	ADV
easat-284	140	9	at	at	ADP
easat-284	140	10	alveolar	alveolar	ADJ
easat-284	140	11	space	space	NOUN
easat-284	140	12	,	,	PUNCT
easat-284	140	13	where	where	SCONJ
easat-284	140	14	serpina134	serpina134	PROPN
easat-284	140	15	strongly	strongly	ADV
easat-284	140	16	and	and	CCONJ
easat-284	140	17	specifically	specifically	ADV
easat-284	140	18	inhi	inhi	PROPN
easat-284	140	19	bits	bits	PROPN
easat-284	140	20	neutrophil	neutrophil	PROPN
easat-284	140	21	elastase	elastase	NOUN
easat-284	140	22	.	.	PUNCT
easat-284	141	1	when	when	SCONJ
easat-284	141	2	the	the	DET
easat-284	141	3	inhibitor	inhibitor	NOUN
easat-284	141	4	concentration	concentration	NOUN
easat-284	141	5	is	be	AUX
easat-284	141	6	sufficient	sufficient	ADJ
easat-284	141	7	to	to	PART
easat-284	141	8	block	block	VERB
easat-284	141	9	released	release	VERB
easat-284	141	10	elastase	elastase	NOUN
easat-284	141	11	,	,	PUNCT
easat-284	141	12	no	no	DET
easat-284	141	13	lesion	lesion	NOUN
easat-284	141	14	happens	happen	VERB
easat-284	141	15	nor	nor	CCONJ
easat-284	141	16	in	in	ADP
easat-284	141	17	alve	alve	NOUN
easat-284	141	18	olar	olar	ADJ
easat-284	141	19	epithelium	epithelium	NOUN
easat-284	141	20	nor	nor	CCONJ
easat-284	141	21	in	in	ADP
easat-284	141	22	alveolar	alveolar	ADJ
easat-284	141	23	endothelial	endothelial	ADJ
easat-284	141	24	wall	wall	NOUN
easat-284	141	25	and	and	CCONJ
easat-284	141	26	this	this	PRON
easat-284	141	27	corresponds	correspond	VERB
easat-284	141	28	with	with	ADP
easat-284	141	29	the	the	DET
easat-284	141	30	moderate	moderate	ADJ
easat-284	141	31	covid	covid	NOUN
easat-284	141	32	-19	-19	PUNCT
easat-284	141	33	clinical	clinical	ADJ
easat-284	141	34	condition	condition	NOUN
easat-284	141	35	.	.	PUNCT
easat-284	142	1	otherwise	otherwise	ADV
easat-284	142	2	,	,	PUNCT
easat-284	142	3	if	if	SCONJ
easat-284	142	4	serpina135	serpina135	PROPN
easat-284	142	5	is	be	AUX
easat-284	142	6	overhelmed	overhelme	VERB
easat-284	142	7	or	or	CCONJ
easat-284	142	8	is	be	AUX
easat-284	142	9	absent	absent	ADJ
easat-284	142	10	/	/	SYM
easat-284	142	11	deficient	deficient	ADJ
easat-284	142	12	,	,	PUNCT
easat-284	142	13	as	as	ADP
easat-284	142	14	in	in	ADP
easat-284	142	15	homo	homo	NOUN
easat-284	142	16	/	/	SYM
easat-284	142	17	eterozygous	eterozygous	ADJ
easat-284	142	18	patients	patient	NOUN
easat-284	142	19	(	(	PUNCT
easat-284	142	20	about	about	ADV
easat-284	142	21	4	4	NUM
easat-284	142	22	%	%	NOUN
easat-284	142	23	european	european	ADJ
easat-284	142	24	population	population	NOUN
easat-284	142	25	)	)	PUNCT
easat-284	142	26	,	,	PUNCT
easat-284	142	27	imbalance	imbalance	NOUN
easat-284	142	28	between	between	ADP
easat-284	142	29	elastase	elastase	NOUN
easat-284	142	30	and	and	CCONJ
easat-284	142	31	anti	anti	ADJ
easat-284	142	32	-	-	ADJ
easat-284	142	33	elastase	elastase	ADJ
easat-284	142	34	activity	activity	NOUN
easat-284	142	35	,	,	PUNCT
easat-284	142	36	free	free	ADJ
easat-284	142	37	elastase	elastase	NOUN
easat-284	142	38	causes	cause	VERB
easat-284	142	39	progressive	progressive	ADJ
easat-284	142	40	damage	damage	NOUN
easat-284	142	41	of	of	ADP
easat-284	142	42	both	both	DET
easat-284	142	43	alveoli	alveoli	NOUN
easat-284	142	44	and	and	CCONJ
easat-284	142	45	endothelium	endothelium	NOUN
easat-284	142	46	,	,	PUNCT
easat-284	142	47	inducing	induce	VERB
easat-284	142	48	endotheliopathy	endotheliopathy	ADJ
easat-284	142	49	and	and	CCONJ
easat-284	142	50	thrombogenic	thrombogenic	ADJ
easat-284	142	51	state	state	NOUN
easat-284	142	52	previously	previously	ADV
easat-284	142	53	described	describe	VERB
easat-284	142	54	.	.	PUNCT
easat-284	143	1	the	the	DET
easat-284	143	2	hypercoagulability	hypercoagulability	NOUN
easat-284	143	3	,	,	PUNCT
easat-284	143	4	as	as	ADP
easat-284	143	5	unbalance	unbalance	NOUN
easat-284	143	6	of	of	ADP
easat-284	143	7	proteases	protease	NOUN
easat-284	143	8	/	/	SYM
easat-284	143	9	antiproteases	antiprotease	NOUN
easat-284	143	10	cascades	cascade	NOUN
easat-284	143	11	,	,	PUNCT
easat-284	143	12	the	the	DET
easat-284	143	13	decrease	decrease	NOUN
easat-284	143	14	of	of	ADP
easat-284	143	15	adamts13	adamts13	NOUN
easat-284	143	16	,	,	PUNCT
easat-284	143	17	the	the	DET
easat-284	143	18	endotheliopathy	endotheliopathy	NOUN
easat-284	143	19	,	,	PUNCT
easat-284	143	20	the	the	DET
easat-284	143	21	increased	increase	VERB
easat-284	143	22	platelet	platelet	NOUN
easat-284	143	23	activation	activation	NOUN
easat-284	143	24	,	,	PUNCT
easat-284	143	25	the	the	DET
easat-284	143	26	ulvwf	ulvwf	NOUN
easat-284	143	27	multimers	multimer	NOUN
easat-284	143	28	and	and	CCONJ
easat-284	143	29	the	the	DET
easat-284	143	30	netosis	netosis	NOUN
easat-284	143	31	together	together	ADV
easat-284	143	32	create	create	VERB
easat-284	143	33	a	a	DET
easat-284	143	34	severe	severe	ADJ
easat-284	143	35	thromboembolic	thromboembolic	ADJ
easat-284	143	36	environment	environment	NOUN
easat-284	143	37	,	,	PUNCT
easat-284	143	38	similar	similar	ADJ
easat-284	143	39	to	to	ADP
easat-284	143	40	thrombotic	thrombotic	ADJ
easat-284	143	41	thrombocytopenic	thrombocytopenic	ADJ
easat-284	143	42	purpura	purpura	NOUN
easat-284	143	43	/	/	SYM
easat-284	143	44	hus	hus	PART
easat-284	143	45	conditions	condition	NOUN
easat-284	143	46	and	and	CCONJ
easat-284	143	47	acute	acute	ADJ
easat-284	143	48	promyelocytic	promyelocytic	ADJ
easat-284	143	49	leukemia	leukemia	NOUN
easat-284	143	50	activation	activation	NOUN
easat-284	143	51	of	of	ADP
easat-284	143	52	clotting	clot	VERB
easat-284	143	53	systems	system	NOUN
easat-284	143	54	with	with	ADP
easat-284	143	55	secondary	secondary	ADJ
easat-284	143	56	hyperfibrinolysis	hyperfibrinolysis	NOUN
easat-284	144	1	[	[	X
easat-284	144	2	45	45	NUM
easat-284	144	3	,	,	PUNCT
easat-284	144	4	47	47	NUM
easat-284	144	5	,	,	PUNCT
easat-284	144	6	48	48	NUM
easat-284	144	7	]	]	PUNCT
easat-284	144	8	.	.	PUNCT
easat-284	145	1	critical	critical	ADJ
easat-284	145	2	sars	sar	NOUN
easat-284	145	3	-	-	PUNCT
easat-284	145	4	cov-2	cov-2	PART
easat-284	145	5	infection	infection	NOUN
easat-284	145	6	,	,	PUNCT
easat-284	145	7	severe	severe	ADJ
easat-284	145	8	thrombosis	thrombosis	NOUN
easat-284	145	9	,	,	PUNCT
easat-284	145	10	“	"	PUNCT
easat-284	145	11	proteolytic	proteolytic	ADJ
easat-284	145	12	”	"	PUNCT
easat-284	145	13	and	and	CCONJ
easat-284	145	14	“	"	PUNCT
easat-284	145	15	immunological	immunological	ADJ
easat-284	145	16	”	"	PUNCT
easat-284	145	17	storm	storm	NOUN
easat-284	145	18	:	:	PUNCT
easat-284	145	19	the	the	DET
easat-284	145	20	possible	possible	ADJ
easat-284	145	21	role	role	NOUN
easat-284	145	22	of	of	ADP
easat-284	145	23	human	human	ADJ
easat-284	145	24	convalescent	convalescent	NOUN
easat-284	145	25	/	/	SYM
easat-284	145	26	non	non	ADJ
easat-284	145	27	convalescent	convalescent	NOUN
easat-284	145	28	plasma	plasma	NOUN
easat-284	145	29	and	and	CCONJ
easat-284	145	30	of	of	ADP
easat-284	145	31	serine	serine	NOUN
easat-284	145	32	proteases	protease	NOUN
easat-284	145	33	inhibitors	inhibitor	NOUN
easat-284	145	34	as	as	ADP
easat-284	145	35	“	"	PUNCT
easat-284	145	36	firehose	firehose	NOUN
easat-284	145	37	”	"	PUNCT
easat-284	145	38	,	,	PUNCT
easat-284	145	39	due	due	ADP
easat-284	145	40	to	to	ADP
easat-284	145	41	proteolysis	proteolysis	NOUN
easat-284	145	42	inhibitors	inhibitor	NOUN
easat-284	145	43	support	support	NOUN
easat-284	145	44	:	:	PUNCT
easat-284	145	45	convalescent	convalescent	NOUN
easat-284	145	46	plasma	plasma	NOUN
easat-284	145	47	(	(	PUNCT
easat-284	145	48	cp	cp	NOUN
easat-284	145	49	)	)	PUNCT
easat-284	145	50	use	use	NOUN
easat-284	145	51	in	in	ADP
easat-284	145	52	the	the	DET
easat-284	145	53	therapy	therapy	NOUN
easat-284	145	54	of	of	ADP
easat-284	145	55	untreatable	untreatable	ADJ
easat-284	145	56	infectious	infectious	ADJ
easat-284	145	57	diseases	disease	NOUN
easat-284	145	58	has	have	AUX
easat-284	145	59	been	be	AUX
easat-284	145	60	extensively	extensively	ADV
easat-284	145	61	but	but	CCONJ
easat-284	145	62	anecdotally	anecdotally	ADV
easat-284	145	63	documented	document	VERB
easat-284	145	64	,	,	PUNCT
easat-284	145	65	including	include	VERB
easat-284	145	66	spanish	spanish	ADJ
easat-284	145	67	influenza	influenza	NOUN
easat-284	145	68	a	a	DET
easat-284	145	69	(	(	PUNCT
easat-284	145	70	h1n1	h1n1	NOUN
easat-284	145	71	)	)	PUNCT
easat-284	145	72	infections	infection	NOUN
easat-284	145	73	in	in	ADP
easat-284	145	74	1915	1915	NUM
easat-284	145	75	to	to	ADP
easat-284	145	76	1917	1917	NUM
easat-284	145	77	,	,	PUNCT
easat-284	145	78	severe	severe	ADJ
easat-284	145	79	acute	acute	ADJ
easat-284	145	80	respiratory	respiratory	ADJ
easat-284	145	81	syndrome	syndrome	NOUN
easat-284	145	82	(	(	PUNCT
easat-284	145	83	sars	sars	PROPN
easat-284	145	84	)	)	PUNCT
easat-284	145	85	in	in	ADP
easat-284	145	86	2003	2003	NUM
easat-284	145	87	,	,	PUNCT
easat-284	145	88	pandemic	pandemic	ADJ
easat-284	145	89	2	2	NUM
easat-284	145	90	00	00	SYM
easat-284	145	91	9	9	NUM
easat-284	145	92	influenza	influenza	NOUN
easat-284	145	93	a	a	DET
easat-284	145	94	(	(	PUNCT
easat-284	145	95	h1n1	h1n1	NOUN
easat-284	145	96	)	)	PUNCT
easat-284	145	97	,	,	PUNCT
easat-284	145	98	avian	avian	ADJ
easat-284	145	99	influenza	influenza	NOUN
easat-284	145	100	a	a	DET
easat-284	145	101	(	(	PUNCT
easat-284	145	102	h5n1	h5n1	NOUN
easat-284	145	103	)	)	PUNCT
easat-284	145	104	and	and	CCONJ
easat-284	145	105	several	several	ADJ
easat-284	145	106	hemorrhagic	hemorrhagic	NOUN
easat-284	145	107	fevers	fever	NOUN
easat-284	145	108	such	such	ADJ
easat-284	145	109	as	as	ADP
easat-284	145	110	ebola	ebola	PROPN
easat-284	145	111	.	.	PUNCT
easat-284	146	1	based	base	VERB
easat-284	146	2	on	on	ADP
easat-284	146	3	studies	study	NOUN
easat-284	146	4	,	,	PUNCT
easat-284	146	5	showing	show	VERB
easat-284	146	6	convalescent	convalescent	NOUN
easat-284	146	7	plasma	plasma	NOUN
easat-284	146	8	antibodies	antibody	NOUN
easat-284	146	9	can	can	AUX
easat-284	146	10	limit	limit	VERB
easat-284	146	11	the	the	DET
easat-284	146	12	virus	virus	NOUN
easat-284	146	13	reproduction	reproduction	NOUN
easat-284	146	14	,	,	PUNCT
easat-284	146	15	cp	cp	PROPN
easat-284	146	16	has	have	AUX
easat-284	146	17	been	be	AUX
easat-284	146	18	considered	consider	VERB
easat-284	146	19	for	for	ADP
easat-284	146	20	critically	critically	ADV
easat-284	146	21	sick	sick	ADJ
easat-284	146	22	covid‐19	covid‐19	PROPN
easat-284	146	23	patients	patient	NOUN
easat-284	146	24	[	[	X
easat-284	146	25	49	49	NUM
easat-284	146	26	]	]	PUNCT
easat-284	146	27	.	.	PUNCT
easat-284	147	1	in	in	ADP
easat-284	147	2	sars	sars	PROPN
easat-284	147	3	-	-	PUNCT
easat-284	147	4	cov	cov	PROPN
easat-284	147	5	and	and	CCONJ
easat-284	147	6	mers	mer	NOUN
easat-284	147	7	,	,	PUNCT
easat-284	147	8	cp	cp	PROPN
easat-284	147	9	was	be	AUX
easat-284	147	10	shown	show	VERB
easat-284	147	11	to	to	PART
easat-284	147	12	provide	provide	VERB
easat-284	147	13	nabs	nab	NOUN
easat-284	147	14	binding	bind	VERB
easat-284	147	15	to	to	ADP
easat-284	147	16	spike1	spike1	NOUN
easat-284	147	17	-	-	PUNCT
easat-284	147	18	receptor	receptor	NOUN
easat-284	147	19	binding	bind	VERB
easat-284	147	20	protein	protein	NOUN
easat-284	147	21	(	(	PUNCT
easat-284	147	22	s1	s1	NOUN
easat-284	147	23	-	-	PUNCT
easat-284	147	24	rbd	rbd	NOUN
easat-284	147	25	)	)	PUNCT
easat-284	147	26	,	,	PUNCT
easat-284	147	27	s1	s1	NOUN
easat-284	147	28	-	-	PUNCT
easat-284	147	29	n	n	CCONJ
easat-284	147	30	-	-	PUNCT
easat-284	147	31	terminal	terminal	ADJ
easat-284	147	32	domain	domain	NOUN
easat-284	147	33	and	and	CCONJ
easat-284	147	34	s2	s2	PROPN
easat-284	147	35	,	,	PUNCT
easat-284	147	36	thus	thus	ADV
easat-284	147	37	blocking	block	VERB
easat-284	147	38	entry	entry	NOUN
easat-284	147	39	and	and	CCONJ
easat-284	147	40	containing	contain	VERB
easat-284	147	41	viral	viral	ADJ
easat-284	147	42	amplification	amplification	NOUN
easat-284	147	43	.	.	PUNCT
easat-284	148	1	very	very	ADV
easat-284	148	2	recently	recently	ADV
easat-284	148	3	,	,	PUNCT
easat-284	148	4	cochrane	cochrane	NOUN
easat-284	148	5	database	database	NOUN
easat-284	148	6	of	of	ADP
easat-284	148	7	systematic	systematic	ADJ
easat-284	148	8	reviews	review	NOUN
easat-284	148	9	published	publish	VERB
easat-284	148	10	a	a	DET
easat-284	148	11	rapid	rapid	ADJ
easat-284	148	12	review	review	NOUN
easat-284	148	13	on	on	ADP
easat-284	148	14	convalescent	convalescent	NOUN
easat-284	148	15	plasma	plasma	NOUN
easat-284	148	16	or	or	CCONJ
easat-284	148	17	hyperimmune	hyperimmune	NOUN
easat-284	148	18	immunoglobulin	immunoglobulin	NOUN
easat-284	148	19	for	for	ADP
easat-284	148	20	people	people	NOUN
easat-284	148	21	with	with	ADP
easat-284	148	22	covid-19	covid-19	PROPN
easat-284	148	23	[	[	X
easat-284	148	24	50	50	NUM
easat-284	148	25	]	]	PUNCT
easat-284	148	26	.	.	PUNCT
easat-284	149	1	including	include	VERB
easat-284	149	2	19	19	NUM
easat-284	149	3	studies	study	NOUN
easat-284	149	4	(	(	PUNCT
easat-284	149	5	2	2	NUM
easat-284	149	6	rcts	rct	NOUN
easat-284	149	7	,	,	PUNCT
easat-284	149	8	8	8	NUM
easat-284	149	9	controlled	control	VERB
easat-284	149	10	nrsis	nrsis	NOUN
easat-284	149	11	,	,	PUNCT
easat-284	149	12	9	9	NUM
easat-284	149	13	non‐controlled	non‐controlle	VERB
easat-284	149	14	nrsis	nrsis	NOUN
easat-284	149	15	)	)	PUNCT
easat-284	149	16	with	with	ADP
easat-284	149	17	38,160	38,160	NUM
easat-284	149	18	participants	participant	NOUN
easat-284	149	19	,	,	PUNCT
easat-284	149	20	of	of	ADP
easat-284	149	21	whom	whom	PRON
easat-284	149	22	36,081	36,081	NUM
easat-284	149	23	received	receive	VERB
easat-284	149	24	convalescent	convalescent	NOUN
easat-284	149	25	plasma	plasma	NOUN
easat-284	149	26	.	.	PUNCT
easat-284	150	1	two	two	NUM
easat-284	150	2	completed	complete	VERB
easat-284	150	3	rcts	rct	NOUN
easat-284	150	4	are	be	AUX
easat-284	150	5	awaiting	await	VERB
easat-284	150	6	assessment	assessment	NOUN
easat-284	150	7	(	(	PUNCT
easat-284	150	8	published	publish	VERB
easat-284	150	9	after	after	ADP
easat-284	150	10	19	19	NUM
easat-284	150	11	august	august	PROPN
easat-284	150	12	2020	2020	NUM
easat-284	150	13	)	)	PUNCT
easat-284	150	14	.	.	PUNCT
easat-284	151	1	were	be	AUX
easat-284	151	2	identified	identify	VERB
easat-284	151	3	a	a	DET
easat-284	151	4	further	further	ADJ
easat-284	151	5	138	138	NUM
easat-284	151	6	ongoing	ongoing	ADJ
easat-284	151	7	studies	study	NOUN
easat-284	151	8	evaluating	evaluate	VERB
easat-284	151	9	convalescent	convalescent	NOUN
easat-284	151	10	plasma	plasma	NOUN
easat-284	151	11	or	or	CCONJ
easat-284	151	12	hyperimmune	hyperimmune	NOUN
easat-284	151	13	immunoglobulin	immunoglobulin	NOUN
easat-284	151	14	,	,	PUNCT
easat-284	151	15	of	of	ADP
easat-284	151	16	which	which	PRON
easat-284	151	17	73	73	NUM
easat-284	151	18	are	be	AUX
easat-284	151	19	randomised	randomise	VERB
easat-284	151	20	(	(	PUNCT
easat-284	151	21	3	3	NUM
easat-284	151	22	reported	report	VERB
easat-284	151	23	in	in	ADP
easat-284	151	24	a	a	DET
easat-284	151	25	study	study	NOUN
easat-284	151	26	registry	registry	NOUN
easat-284	151	27	as	as	ADP
easat-284	151	28	already	already	ADV
easat-284	151	29	being	be	AUX
easat-284	151	30	completed	complete	VERB
easat-284	151	31	,	,	PUNCT
easat-284	151	32	but	but	CCONJ
easat-284	151	33	without	without	ADP
easat-284	151	34	results	result	NOUN
easat-284	151	35	)	)	PUNCT
easat-284	151	36	.	.	PUNCT
easat-284	152	1	no	no	DET
easat-284	152	2	completed	complete	VERB
easat-284	152	3	studie	studie	PROPN
easat-284	152	4	s	s	PART
easat-284	152	5	evaluating	evaluating	NOUN
easat-284	152	6	hyperimmune	hyperimmune	NOUN
easat-284	152	7	immunoglobulin	immunoglobulin	NOUN
easat-284	152	8	was	be	AUX
easat-284	152	9	identified	identify	VERB
easat-284	152	10	.	.	PUNCT
easat-284	153	1	the	the	DET
easat-284	153	2	review	review	NOUN
easat-284	153	3	also	also	ADV
easat-284	153	4	includes	include	VERB
easat-284	153	5	results	result	NOUN
easat-284	153	6	from	from	ADP
easat-284	153	7	two	two	NUM
easat-284	153	8	rcts	rct	NOUN
easat-284	153	9	(	(	PUNCT
easat-284	153	10	both	both	PRON
easat-284	153	11	stopped	stop	VERB
easat-284	153	12	early	early	ADV
easat-284	153	13	)	)	PUNCT
easat-284	153	14	with	with	ADP
easat-284	153	15	189	189	NUM
easat-284	153	16	participants	participant	NOUN
easat-284	153	17	,	,	PUNCT
easat-284	153	18	of	of	ADP
easat-284	153	19	whom	whom	PRON
easat-284	153	20	95	95	NUM
easat-284	153	21	received	receive	VERB
easat-284	153	22	convalescent	convalescent	NOUN
easat-284	153	23	plasma	plasma	NOUN
easat-284	153	24	.	.	PUNCT
easat-284	154	1	control	control	NOUN
easat-284	154	2	groups	group	NOUN
easat-284	154	3	received	receive	VERB
easat-284	154	4	standard	standard	ADJ
easat-284	154	5	care	care	NOUN
easat-284	154	6	at	at	ADP
easat-284	154	7	time	time	NOUN
easat-284	154	8	of	of	ADP
easat-284	154	9	treatment	treatment	NOUN
easat-284	154	10	without	without	ADP
easat-284	154	11	convalescent	convalescent	NOUN
easat-284	154	12	plasma	plasma	NOUN
easat-284	154	13	.	.	PUNCT
easat-284	155	1	the	the	DET
easat-284	155	2	conclusions	conclusion	NOUN
easat-284	155	3	of	of	ADP
easat-284	155	4	the	the	DET
easat-284	155	5	review	review	NOUN
easat-284	155	6	are	be	AUX
easat-284	155	7	uncertain	uncertain	ADJ
easat-284	155	8	whether	whether	SCONJ
easat-284	155	9	convalescent	convalescent	NOUN
easat-284	155	10	plasma	plasma	NOUN
easat-284	155	11	decreases	decrease	VERB
easat-284	155	12	all‐cause	all‐cause	VERB
easat-284	155	13	mortality	mortality	NOUN
easat-284	155	14	at	at	ADP
easat-284	155	15	hospital	hospital	NOUN
easat-284	155	16	discharge	discharge	NOUN
easat-284	155	17	(	(	PUNCT
easat-284	155	18	risk	risk	NOUN
easat-284	155	19	ratio	ratio	NOUN
easat-284	155	20	(	(	PUNCT
easat-284	155	21	rr	rr	NOUN
easat-284	155	22	)	)	PUNCT
easat-284	155	23	0.55	0.55	NUM
easat-284	155	24	,	,	PUNCT
easat-284	155	25	95	95	NUM
easat-284	155	26	%	%	NOUN
easat-284	155	27	confidence	confidence	NOUN
easat-284	155	28	interval	interval	NOUN
easat-284	155	29	(	(	PUNCT
easat-284	155	30	ci	ci	NOUN
easat-284	155	31	)	)	PUNCT
easat-284	155	32	0.22	0.22	NUM
easat-284	155	33	to	to	ADP
easat-284	155	34	1.34	1.34	NUM
easat-284	155	35	;	;	PUNCT
easat-284	155	36	1	1	NUM
easat-284	155	37	rct	rct	PROPN
easat-284	155	38	,	,	PUNCT
easat-284	155	39	86	86	NUM
easat-284	155	40	participants	participant	NOUN
easat-284	155	41	;	;	PUNCT
easat-284	155	42	low	low	ADJ
easat-284	155	43	‐certainty	‐certainty	NUM
easat-284	155	44	evidence	evidence	NOUN
easat-284	155	45	)	)	PUNCT
easat-284	155	46	and	and	CCONJ
easat-284	155	47	whether	whether	SCONJ
easat-284	155	48	convalescent	convalescent	NOUN
easat-284	155	49	plasma	plasma	NOUN
easat-284	155	50	decreases	decrease	VERB
easat-284	155	51	mortality	mortality	NOUN
easat-284	155	52	(	(	PUNCT
easat-284	155	53	time	time	NOUN
easat-284	155	54	to	to	ADP
easat-284	155	55	event	event	NOUN
easat-284	155	56	)	)	PUNCT
easat-284	155	57	(	(	PUNCT
easat-284	155	58	hazard	hazard	NOUN
easat-284	155	59	ratio	ratio	NOUN
easat-284	155	60	(	(	PUNCT
easat-284	155	61	hr	hr	NOUN
easat-284	155	62	)	)	PUNCT
easat-284	155	63	0.64	0.64	NUM
easat-284	155	64	,	,	PUNCT
easat-284	155	65	95	95	NUM
easat-284	155	66	%	%	NOUN
easat-284	155	67	ci	ci	NOUN
easat-284	155	68	0.33	0.33	NUM
easat-284	155	69	to	to	ADP
easat-284	155	70	1.25	1.25	NUM
easat-284	155	71	;	;	PUNCT
easat-284	155	72	2	2	NUM
easat-284	155	73	rcts	rct	NOUN
easat-284	155	74	,	,	PUNCT
easat-284	155	75	189	189	NUM
easat-284	155	76	participants	participant	NOUN
easat-284	155	77	;	;	PUNCT
easat-284	155	78	low‐certainty	low‐certainty	NUM
easat-284	155	79	evidence	evidence	NOUN
easat-284	155	80	)	)	PUNCT
easat-284	155	81	.	.	PUNCT
easat-284	156	1	convalescent	convalescent	NOUN
easat-284	156	2	plasma	plasma	NOUN
easat-284	156	3	may	may	AUX
easat-284	156	4	result	result	VERB
easat-284	156	5	in	in	ADP
easat-284	156	6	little	little	ADJ
easat-284	156	7	to	to	PART
easat-284	156	8	no	no	DET
easat-284	156	9	difference	difference	NOUN
easat-284	156	10	in	in	ADP
easat-284	156	11	improvement	improvement	NOUN
easat-284	156	12	of	of	ADP
easat-284	156	13	clinical	clinical	ADJ
easat-284	156	14	symptoms	symptom	NOUN
easat-284	156	15	(	(	PUNCT
easat-284	156	16	i.e.	i.e.	X
easat-284	156	17	need	need	VERB
easat-284	156	18	for	for	ADP
easat-284	156	19	respi	respi	NOUN
easat-284	156	20	ratory	ratory	ADJ
easat-284	156	21	support	support	NOUN
easat-284	156	22	)	)	PUNCT
easat-284	156	23	at	at	ADP
easat-284	156	24	seven	seven	NUM
easat-284	156	25	days	day	NOUN
easat-284	156	26	(	(	PUNCT
easat-284	156	27	rr	rr	NOUN
easat-284	156	28	0.98	0.98	NUM
easat-284	156	29	,	,	PUNCT
easat-284	156	30	95	95	NUM
easat-284	156	31	%	%	NOUN
easat-284	156	32	ci	ci	NOUN
easat-284	156	33	0.30	0.30	NUM
easat-284	156	34	to	to	ADP
easat-284	156	35	3.19	3.19	NUM
easat-284	156	36	;	;	PUNCT
easat-284	156	37	1	1	NUM
easat-284	156	38	rct	rct	PROPN
easat-284	156	39	,	,	PUNCT
easat-284	156	40	103	103	NUM
easat-284	156	41	participants	participant	NOUN
easat-284	156	42	;	;	PUNCT
easat-284	156	43	low‐certainty	low‐certainty	NUM
easat-284	156	44	evidence	evidence	NOUN
easat-284	156	45	)	)	PUNCT
easat-284	156	46	.	.	PUNCT
easat-284	157	1	convalescent	convalescent	NOUN
easat-284	157	2	plasma	plasma	NOUN
easat-284	157	3	may	may	AUX
easat-284	157	4	increase	increase	VERB
easat-284	157	5	improvement	improvement	NOUN
easat-284	157	6	of	of	ADP
easat-284	157	7	clinical	clinical	ADJ
easat-284	157	8	symptoms	symptom	NOUN
easat-284	157	9	at	at	ADP
easat-284	157	10	up	up	ADP
easat-284	157	11	to	to	PART
easat-284	157	12	15	15	NUM
easat-284	157	13	days	day	NOUN
easat-284	157	14	(	(	PUNCT
easat-284	157	15	rr	rr	NOUN
easat-284	157	16	1.34	1.34	NUM
easat-284	157	17	,	,	PUNCT
easat-284	157	18	95	95	NUM
easat-284	157	19	%	%	NOUN
easat-284	157	20	ci	ci	NOUN
easat-284	157	21	0.85	0.85	NUM
easat-284	157	22	to	to	ADP
easat-284	157	23	2.11	2.11	NUM
easat-284	157	24	;	;	PUNCT
easat-284	157	25	2	2	NUM
easat-284	157	26	rcts	rct	NOUN
easat-284	157	27	,	,	PUNCT
easat-284	157	28	189	189	NUM
easat-284	157	29	participants	participant	NOUN
easat-284	157	30	;	;	PUNCT
easat-284	157	31	low	low	ADJ
easat-284	157	32	‐certainty	‐certainty	NUM
easat-284	157	33	evidence	evidence	NOUN
easat-284	157	34	)	)	PUNCT
easat-284	157	35	,	,	PUNCT
easat-284	157	36	and	and	CCONJ
easat-284	157	37	at	at	ADP
easat-284	157	38	up	up	ADP
easat-284	157	39	to	to	PART
easat-284	157	40	30	30	NUM
easat-284	157	41	days	day	NOUN
easat-284	157	42	(	(	PUNCT
easat-284	157	43	rr	rr	NOUN
easat-284	157	44	1.13	1.13	NUM
easat-284	157	45	,	,	PUNCT
easat-284	157	46	95	95	NUM
easat-284	157	47	%	%	NOUN
easat-284	157	48	ci	ci	NOUN
easat-284	157	49	0.88	0.88	NUM
easat-284	157	50	to	to	ADP
easat-284	157	51	1.43	1.43	NUM
easat-284	157	52	;	;	PUNCT
easat-284	157	53	2	2	NUM
easat-284	157	54	studies	study	NOUN
easat-284	157	55	,	,	PUNCT
easat-284	157	56	188	188	NUM
easat-284	157	57	participants	participant	NOUN
easat-284	157	58	;	;	PUNCT
easat-284	157	59	low‐certainty	low‐certainty	NUM
easat-284	157	60	evidence	evidence	NOUN
easat-284	157	61	)	)	PUNCT
easat-284	157	62	.	.	PUNCT
easat-284	158	1	no	no	DET
easat-284	158	2	studies	study	NOUN
easat-284	158	3	reported	report	VERB
easat-284	158	4	on	on	ADP
easat-284	158	5	quality	quality	NOUN
easat-284	158	6	of	of	ADP
easat-284	158	7	life	life	NOUN
easat-284	158	8	.	.	PUNCT
easat-284	159	1	reporting	reporting	NOUN
easat-284	159	2	of	of	ADP
easat-284	159	3	safety	safety	NOUN
easat-284	159	4	data	datum	NOUN
easat-284	159	5	and	and	CCONJ
easat-284	159	6	duration	duration	NOUN
easat-284	159	7	of	of	ADP
easat-284	159	8	follow‐up	follow‐up	PROPN
easat-284	159	9	was	be	AUX
easat-284	159	10	variable	variable	ADJ
easat-284	159	11	.	.	PUNCT
easat-284	160	1	the	the	DET
easat-284	160	2	controlled	control	VERB
easat-284	160	3	studies	study	NOUN
easat-284	160	4	reported	report	VERB
easat-284	160	5	on	on	ADP
easat-284	160	6	adverse	adverse	ADJ
easat-284	160	7	events	event	NOUN
easat-284	160	8	(	(	PUNCT
easat-284	160	9	aes	aes	NOUN
easat-284	160	10	)	)	PUNCT
easat-284	160	11	and	and	CCONJ
easat-284	160	12	severe	severe	ADJ
easat-284	160	13	adverse	adverse	ADJ
easat-284	160	14	events	event	NOUN
easat-284	160	15	(	(	PUNCT
easat-284	160	16	saes	sae	NOUN
easat-284	160	17	)	)	PUNCT
easat-284	160	18	only	only	ADV
easat-284	160	19	in	in	ADP
easat-284	160	20	participants	participant	NOUN
easat-284	160	21	receiving	receive	VERB
easat-284	160	22	convalescent	convalescent	NOUN
easat-284	160	23	plasma	plasma	NOUN
easat-284	160	24	.	.	PUNCT
easat-284	161	1	some	some	PRON
easat-284	161	2	,	,	PUNCT
easat-284	161	3	but	but	CCONJ
easat-284	161	4	not	not	PART
easat-284	161	5	all	all	PRON
easat-284	161	6	,	,	PUNCT
easat-284	161	7	studies	study	NOUN
easat-284	161	8	included	include	VERB
easat-284	161	9	death	death	NOUN
easat-284	161	10	as	as	ADP
easat-284	161	11	a	a	DET
easat-284	161	12	sae	sae	PROPN
easat-284	161	13	.	.	PUNCT
easat-284	162	1	the	the	DET
easat-284	162	2	studies	study	NOUN
easat-284	162	3	did	do	AUX
easat-284	162	4	not	not	PART
easat-284	162	5	report	report	VERB
easat-284	162	6	the	the	DET
easat-284	162	7	grade	grade	NOUN
easat-284	162	8	of	of	ADP
easat-284	162	9	aes	aes	PROPN
easat-284	162	10	.	.	PROPN
easat-284	163	1	fourteen	fourteen	NUM
easat-284	163	2	studies	study	NOUN
easat-284	163	3	(	(	PUNCT
easat-284	163	4	566	566	NUM
easat-284	163	5	participants	participant	NOUN
easat-284	163	6	)	)	PUNCT
easat-284	163	7	re	re	VERB
easat-284	163	8	ported	port	VERB
easat-284	163	9	on	on	ADP
easat-284	163	10	aes	aes	PROPN
easat-284	163	11	of	of	ADP
easat-284	163	12	possible	possible	ADJ
easat-284	163	13	grade	grade	NOUN
easat-284	163	14	3	3	NUM
easat-284	163	15	or	or	CCONJ
easat-284	163	16	4	4	NUM
easat-284	163	17	severity	severity	NOUN
easat-284	163	18	.	.	PUNCT
easat-284	164	1	the	the	DET
easat-284	164	2	majority	majority	NOUN
easat-284	164	3	of	of	ADP
easat-284	164	4	these	these	DET
easat-284	164	5	aes	aes	NOUN
easat-284	164	6	were	be	AUX
easat-284	164	7	allergic	allergic	ADJ
easat-284	164	8	or	or	CCONJ
easat-284	164	9	respiratory	respiratory	ADJ
easat-284	164	10	events	event	NOUN
easat-284	164	11	.	.	PUNCT
easat-284	165	1	the	the	DET
easat-284	165	2	studies	study	NOUN
easat-284	165	3	are	be	AUX
easat-284	165	4	very	very	ADV
easat-284	165	5	uncertain	uncertain	ADJ
easat-284	165	6	whether	whether	SCONJ
easat-284	165	7	convalescent	convalescent	NOUN
easat-284	165	8	plasma	plasma	NOUN
easat-284	165	9	therapy	therapy	NOUN
easat-284	165	10	affects	affect	VERB
easat-284	165	11	the	the	DET
easat-284	165	12	risk	risk	NOUN
easat-284	165	13	of	of	ADP
easat-284	165	14	moderate	moderate	ADJ
easat-284	165	15	to	to	ADP
easat-284	165	16	severe	severe	ADJ
easat-284	165	17	aes	aes	PROPN
easat-284	165	18	(	(	PUNCT
easat-284	165	19	very	very	ADV
easat-284	165	20	low‐certainty	low‐certainty	NUM
easat-284	165	21	evidence	evidence	NOUN
easat-284	165	22	)	)	PUNCT
easat-284	165	23	.	.	PUNCT
easat-284	166	1	17	17	NUM
easat-284	166	2	studies	study	NOUN
easat-284	166	3	(	(	PUNCT
easat-284	166	4	35,944	35,944	NUM
easat-284	166	5	participants	participant	NOUN
easat-284	166	6	)	)	PUNCT
easat-284	166	7	assessed	assess	VERB
easat-284	166	8	saes	sae	NOUN
easat-284	166	9	for	for	ADP
easat-284	166	10	20,622	20,622	NUM
easat-284	166	11	of	of	ADP
easat-284	166	12	its	its	PRON
easat-284	166	13	participants	participant	NOUN
easat-284	166	14	.	.	PUNCT
easat-284	167	1	the	the	DET
easat-284	167	2	majority	majority	NOUN
easat-284	167	3	of	of	ADP
easat-284	167	4	participants	participant	NOUN
easat-284	167	5	were	be	AUX
easat-284	167	6	from	from	ADP
easat-284	167	7	one	one	NUM
easat-284	167	8	non‐controlled	non‐controlle	VERB
easat-284	167	9	nrsi	nrsi	NOUN
easat-284	167	10	(	(	PUNCT
easat-284	167	11	20,000	20,000	NUM
easat-284	167	12	participants	participant	NOUN
easat-284	167	13	)	)	PUNCT
easat-284	167	14	,	,	PUNCT
easat-284	167	15	which	which	PRON
easat-284	167	16	reported	report	VERB
easat-284	167	17	on	on	ADP
easat-284	167	18	saes	saes	PROPN
easat-284	167	19	within	within	ADP
easat-284	167	20	the	the	DET
easat-284	167	21	first	first	ADJ
easat-284	167	22	four	four	NUM
easat-284	167	23	hours	hour	NOUN
easat-284	167	24	and	and	CCONJ
easat-284	167	25	within	within	ADP
easat-284	167	26	an	an	DET
easat-284	167	27	additional	additional	ADJ
easat-284	167	28	seven	seven	NUM
easat-284	167	29	days	day	NOUN
easat-284	167	30	after	after	ADP
easat-284	167	31	transfusion	transfusion	NOUN
easat-284	167	32	.	.	PUNCT
easat-284	168	1	there	there	PRON
easat-284	168	2	were	be	VERB
easat-284	168	3	63	63	NUM
easat-284	168	4	deaths	death	NOUN
easat-284	168	5	,	,	PUNCT
easat-284	168	6	12	12	NUM
easat-284	168	7	were	be	AUX
easat-284	168	8	possibl	possibl	PROPN
easat-284	168	9	y	y	PROPN
easat-284	168	10	and	and	CCONJ
easat-284	168	11	one	one	NUM
easat-284	168	12	was	be	AUX
easat-284	168	13	probably	probably	ADV
easat-284	168	14	related	relate	VERB
easat-284	168	15	to	to	ADP
easat-284	168	16	transfusion	transfusion	NOUN
easat-284	168	17	.	.	PUNCT
easat-284	169	1	there	there	PRON
easat-284	169	2	were	be	VERB
easat-284	169	3	146	146	NUM
easat-284	169	4	saes	sae	NOUN
easat-284	169	5	within	within	ADP
easat-284	169	6	four	four	NUM
easat-284	169	7	hours	hour	NOUN
easat-284	169	8	and	and	CCONJ
easat-284	169	9	1136	1136	NUM
easat-284	169	10	saes	sae	NOUN
easat-284	169	11	within	within	ADP
easat-284	169	12	seven	seven	NUM
easat-284	169	13	days	day	NOUN
easat-284	169	14	post	post	NOUN
easat-284	169	15	‐transfusion	‐transfusion	PROPN
easat-284	169	16	.	.	PUNCT
easat-284	170	1	these	these	PRON
easat-284	170	2	were	be	AUX
easat-284	170	3	predominantly	predominantly	ADV
easat-284	170	4	allergic	allergic	ADJ
easat-284	170	5	or	or	CCONJ
easat-284	170	6	respiratory	respiratory	ADJ
easat-284	170	7	,	,	PUNCT
easat-284	170	8	thrombotic	thrombotic	ADJ
easat-284	170	9	or	or	CCONJ
easat-284	170	10	thromboembolic	thromboembolic	ADJ
easat-284	170	11	and	and	CCONJ
easat-284	170	12	cardiac	cardiac	ADJ
easat-284	170	13	events	event	NOUN
easat-284	170	14	.	.	PUNCT
easat-284	171	1	a	a	DET
easat-284	171	2	recently	recently	ADV
easat-284	171	3	published	publish	VERB
easat-284	171	4	randomized	randomize	VERB
easat-284	171	5	clinical	clinical	ADJ
easat-284	171	6	trial	trial	NOUN
easat-284	171	7	published	publish	VERB
easat-284	171	8	by	by	ADP
easat-284	171	9	plasmar	plasmar	NOUN
easat-284	171	10	study	study	NOUN
easat-284	171	11	group	group	NOUN
easat-284	171	12	has	have	AUX
easat-284	171	13	concluded	conclude	VERB
easat-284	171	14	that	that	SCONJ
easat-284	171	15	no	no	DET
easat-284	171	16	significant	significant	ADJ
easat-284	171	17	differences	difference	NOUN
easat-284	171	18	were	be	AUX
easat-284	171	19	observed	observe	VERB
easat-284	171	20	in	in	ADP
easat-284	171	21	clinical	clinical	ADJ
easat-284	171	22	status	status	NOUN
easat-284	171	23	or	or	CCONJ
easat-284	171	24	overall	overall	ADJ
easat-284	171	25	mortality	mortality	NOUN
easat-284	171	26	between	between	ADP
easat-284	171	27	patients	patient	NOUN
easat-284	171	28	treated	treat	VERB
easat-284	171	29	with	with	ADP
easat-284	171	30	convalescent	convalescent	NOUN
easat-284	171	31	plasma	plasma	NOUN
easat-284	171	32	and	and	CCONJ
easat-284	171	33	those	those	PRON
easat-284	171	34	who	who	PRON
easat-284	171	35	receive	receive	VERB
easat-284	171	36	d	d	DET
easat-284	171	37	placebo	placebo	NOUN
easat-284	171	38	[	[	X
easat-284	171	39	51	51	NUM
easat-284	171	40	]	]	PUNCT
easat-284	171	41	.	.	PUNCT
easat-284	172	1	all	all	DET
easat-284	172	2	these	these	DET
easat-284	172	3	studies	study	NOUN
easat-284	172	4	were	be	AUX
easat-284	172	5	using	use	VERB
easat-284	172	6	not	not	PART
easat-284	172	7	more	more	ADJ
easat-284	172	8	than	than	ADP
easat-284	172	9	500	500	NUM
easat-284	172	10	ml	ml	NOUN
easat-284	172	11	of	of	ADP
easat-284	172	12	convalescent	convalescent	NOUN
easat-284	172	13	plasma	plasma	NOUN
easat-284	172	14	and	and	CCONJ
easat-284	172	15	the	the	DET
easat-284	172	16	scientific	scientific	ADJ
easat-284	172	17	reason	reason	NOUN
easat-284	172	18	for	for	ADP
easat-284	172	19	the	the	DET
easat-284	172	20	transfusion	transfusion	NOUN
easat-284	172	21	was	be	AUX
easat-284	172	22	the	the	DET
easat-284	172	23	activity	activity	NOUN
easat-284	172	24	of	of	ADP
easat-284	172	25	neutralising	neutralise	VERB
easat-284	172	26	antibodies	antibody	NOUN
easat-284	172	27	against	against	ADP
easat-284	172	28	sars	sar	NOUN
easat-284	172	29	-	-	PUNCT
easat-284	172	30	cov-2	cov-2	NOUN
easat-284	172	31	.	.	PUNCT
easat-284	173	1	in	in	ADP
easat-284	173	2	this	this	DET
easat-284	173	3	paper	paper	NOUN
easat-284	173	4	,	,	PUNCT
easat-284	173	5	on	on	ADP
easat-284	173	6	the	the	DET
easat-284	173	7	contrary	contrary	NOUN
easat-284	173	8	,	,	PUNCT
easat-284	173	9	we	we	PRON
easat-284	173	10	have	have	AUX
easat-284	173	11	shown	show	VERB
easat-284	173	12	that	that	SCONJ
easat-284	173	13	the	the	DET
easat-284	173	14	worsening	worsening	NOUN
easat-284	173	15	of	of	ADP
easat-284	173	16	covid-19	covid-19	PROPN
easat-284	173	17	clinical	clinical	ADJ
easat-284	173	18	symptoms	symptom	NOUN
easat-284	173	19	is	be	AUX
easat-284	173	20	due	due	ADJ
easat-284	173	21	to	to	ADP
easat-284	173	22	the	the	DET
easat-284	173	23	catastrophic	catastrophic	ADJ
easat-284	173	24	“	"	PUNCT
easat-284	173	25	unfriendly	unfriendly	ADJ
easat-284	173	26	fire	fire	NOUN
easat-284	173	27	”	"	PUNCT
easat-284	173	28	of	of	ADP
easat-284	173	29	recruited	recruit	VERB
easat-284	173	30	neutrophils	neutrophil	NOUN
easat-284	173	31	,	,	PUNCT
easat-284	173	32	with	with	ADP
easat-284	173	33	overhelming	overhelming	NOUN
easat-284	173	34	and	and	CCONJ
easat-284	173	35	imbalancing	imbalance	VERB
easat-284	173	36	of	of	ADP
easat-284	173	37	serine	serine	NOUN
easat-284	173	38	proteolytic	proteolytic	ADJ
easat-284	173	39	cascades	cascade	NOUN
easat-284	173	40	activator	activator	NOUN
easat-284	173	41	proteases	protease	NOUN
easat-284	173	42	over	over	ADP
easat-284	173	43	inhibitors	inhibitor	NOUN
easat-284	173	44	,	,	PUNCT
easat-284	173	45	serious	serious	ADJ
easat-284	173	46	endotheliopathy	endotheliopathy	ADJ
easat-284	173	47	,	,	PUNCT
easat-284	173	48	netosis	netosis	PROPN
easat-284	173	49	,	,	PUNCT
easat-284	173	50	ulvwf	ulvwf	NOUN
easat-284	173	51	release	release	NOUN
easat-284	173	52	,	,	PUNCT
easat-284	173	53	hypercoagulability	hypercoagulability	NOUN
easat-284	173	54	and	and	CCONJ
easat-284	173	55	diffuse	diffuse	PROPN
easat-284	173	56	micro	micro	ADJ
easat-284	173	57	/	/	SYM
easat-284	173	58	macrothrombi	macrothrombi	NOUN
easat-284	173	59	formation	formation	NOUN
easat-284	173	60	.	.	PUNCT
easat-284	174	1	this	this	DET
easat-284	174	2	condition	condition	NOUN
easat-284	174	3	in	in	ADP
easat-284	174	4	the	the	DET
easat-284	174	5	paper	paper	NOUN
easat-284	174	6	has	have	AUX
easat-284	174	7	been	be	AUX
easat-284	174	8	described	describe	VERB
easat-284	174	9	as	as	ADP
easat-284	174	10	“	"	PUNCT
easat-284	174	11	proteolytic	proteolytic	ADJ
easat-284	174	12	storm	storm	NOUN
easat-284	174	13	”	"	PUNCT
easat-284	174	14	,	,	PUNCT
easat-284	174	15	which	which	PRON
easat-284	174	16	advances	advance	VERB
easat-284	174	17	and	and	CCONJ
easat-284	174	18	sustains	sustain	VERB
easat-284	174	19	/	/	PUNCT
easat-284	174	20	is	be	AUX
easat-284	174	21	sustained	sustain	VERB
easat-284	174	22	by	by	ADP
easat-284	174	23	the	the	DET
easat-284	174	24	well	well	ADV
easat-284	174	25	-known	-known	ADJ
easat-284	174	26	“	"	PUNCT
easat-284	174	27	cytokine	cytokine	ADJ
easat-284	174	28	storm”as	storm”as	NOUN
easat-284	174	29	shown	show	VERB
easat-284	174	30	in	in	ADP
easat-284	174	31	figure	figure	NOUN
easat-284	174	32	4	4	NUM
easat-284	174	33	.	.	PUNCT
easat-284	175	1	following	follow	VERB
easat-284	175	2	this	this	DET
easat-284	175	3	hypothesis	hypothesis	NOUN
easat-284	175	4	,	,	PUNCT
easat-284	175	5	human	human	ADJ
easat-284	175	6	plasma	plasma	NOUN
easat-284	175	7	,	,	PUNCT
easat-284	175	8	non	non	ADJ
easat-284	175	9	-	-	ADJ
easat-284	175	10	convalescent	convalescent	ADJ
easat-284	175	11	,	,	PUNCT
easat-284	175	12	should	should	AUX
easat-284	175	13	be	be	AUX
easat-284	175	14	used	use	VERB
easat-284	175	15	in	in	ADP
easat-284	175	16	adequate	adequate	ADJ
easat-284	175	17	quantities	quantity	NOUN
easat-284	175	18	(	(	PUNCT
easat-284	175	19	more	more	ADJ
easat-284	175	20	than	than	ADP
easat-284	175	21	2	2	NUM
easat-284	175	22	liters	liter	NOUN
easat-284	175	23	and/or	and/or	CCONJ
easat-284	175	24	following	follow	VERB
easat-284	175	25	plasma	plasma	NOUN
easat-284	175	26	-	-	PUNCT
easat-284	175	27	exchange	exchange	NOUN
easat-284	175	28	procedures	procedure	NOUN
easat-284	175	29	)	)	PUNCT
easat-284	175	30	as	as	SCONJ
easat-284	175	31	it	it	PRON
easat-284	175	32	supplies	supply	VERB
easat-284	175	33	:	:	PUNCT
easat-284	175	34	•	•	NUM
easat-284	175	35	other	other	ADJ
easat-284	175	36	antibodies	antibodie	VERB
easat-284	175	37	able	able	ADJ
easat-284	175	38	to	to	PART
easat-284	175	39	mediate	mediate	VERB
easat-284	175	40	/	/	SYM
easat-284	175	41	neutralize	neutralize	VERB
easat-284	175	42	pathways	pathway	NOUN
easat-284	175	43	such	such	ADJ
easat-284	175	44	as	as	ADP
easat-284	175	45	complement	complement	NOUN
easat-284	175	46	activation	activation	NOUN
easat-284	175	47	,	,	PUNCT
easat-284	175	48	antibody	antibody	NOUN
easat-284	175	49	-	-	PUNCT
easat-284	175	50	dependent	dependent	ADJ
easat-284	175	51	cellular	cellular	ADJ
easat-284	175	52	cytotoxicity	cytotoxicity	NOUN
easat-284	175	53	and/or	and/or	CCONJ
easat-284	175	54	phagocytosis	phagocytosis	VERB
easat-284	175	55	[	[	X
easat-284	175	56	52	52	NUM
easat-284	175	57	,	,	PUNCT
easat-284	175	58	53	53	NUM
easat-284	175	59	]	]	PUNCT
easat-284	175	60	.	.	PUNCT
easat-284	176	1	limiting	limit	VERB
easat-284	176	2	immune	immune	ADJ
easat-284	176	3	complexes	complex	NOUN
easat-284	176	4	formation	formation	NOUN
easat-284	176	5	and	and	CCONJ
easat-284	176	6	cytokine	cytokine	ADJ
easat-284	176	7	release	release	NOUN
easat-284	176	8	such	such	ADJ
easat-284	176	9	as	as	ADP
easat-284	176	10	il-1β	il-1β	PROPN
easat-284	176	11	and	and	CCONJ
easat-284	176	12	tnfα	tnfα	NOUN
easat-284	176	13	•	•	NUM
easat-284	176	14	serpin	serpin	PROPN
easat-284	176	15	family	family	NOUN
easat-284	176	16	serine	serine	NOUN
easat-284	176	17	proteases	protease	NOUN
easat-284	176	18	inhibitors	inhibitor	NOUN
easat-284	176	19	of	of	ADP
easat-284	176	20	the	the	DET
easat-284	176	21	four	four	NUM
easat-284	176	22	interconnected	interconnected	ADJ
easat-284	176	23	proteolytic	proteolytic	ADJ
easat-284	176	24	cascades	cascade	NOUN
easat-284	176	25	(	(	PUNCT
easat-284	176	26	clotting	clotting	NOUN
easat-284	176	27	,	,	PUNCT
easat-284	176	28	complement	complement	NOUN
easat-284	176	29	,	,	PUNCT
easat-284	176	30	fibrinolysis	fibrinolysis	NOUN
easat-284	176	31	and	and	CCONJ
easat-284	176	32	kallikrein	kallikrein	ADJ
easat-284	176	33	)	)	PUNCT
easat-284	176	34	71	71	NUM
easat-284	176	35	edelweiss	edelweiss	PROPN
easat-284	176	36	applied	apply	VERB
easat-284	176	37	science	science	NOUN
easat-284	176	38	and	and	CCONJ
easat-284	176	39	technology	technology	NOUN
easat-284	176	40	issn	issn	PROPN
easat-284	176	41	:	:	PUNCT
easat-284	176	42	2576	2576	NUM
easat-284	176	43	-	-	SYM
easat-284	176	44	8484	8484	NUM
easat-284	176	45	vol	vol	NOUN
easat-284	176	46	.	.	PROPN
easat-284	177	1	4	4	NUM
easat-284	177	2	,	,	PUNCT
easat-284	177	3	no	no	INTJ
easat-284	177	4	.	.	NOUN
easat-284	177	5	1	1	NUM
easat-284	177	6	:	:	SYM
easat-284	177	7	67	67	NUM
easat-284	177	8	-	-	SYM
easat-284	177	9	73	73	NUM
easat-284	177	10	,	,	PUNCT
easat-284	177	11	2020	2020	NUM
easat-284	177	12	doi	doi	NOUN
easat-284	177	13	:	:	PUNCT
easat-284	177	14	10.33805/2576	10.33805/2576	NUM
easat-284	177	15	-	-	SYM
easat-284	177	16	8484.184	8484.184	NUM
easat-284	177	17	©	©	PROPN
easat-284	177	18	2020	2020	NUM
easat-284	177	19	by	by	ADP
easat-284	177	20	the	the	DET
easat-284	177	21	author	author	NOUN
easat-284	177	22	•	•	ADP
easat-284	177	23	adamts13	adamts13	NOUN
easat-284	177	24	supply	supply	NOUN
easat-284	177	25	,	,	PUNCT
easat-284	177	26	which	which	PRON
easat-284	177	27	cleaves	cleave	VERB
easat-284	177	28	ulvwf	ulvwf	NOUN
easat-284	177	29	,	,	PUNCT
easat-284	177	30	reducing	reduce	VERB
easat-284	177	31	hypercoagulability	hypercoagulability	NOUN
easat-284	177	32	and	and	CCONJ
easat-284	177	33	thrombogenicity	thrombogenicity	NOUN
easat-284	177	34	[	[	X
easat-284	177	35	54	54	NUM
easat-284	177	36	]	]	SYM
easat-284	177	37	•	•	NUM
easat-284	177	38	serpina1	serpina1	X
easat-284	177	39	inhibiting	inhibit	VERB
easat-284	177	40	neutrophil	neutrophil	ADJ
easat-284	177	41	elastase	elastase	VERB
easat-284	177	42	deleterious	deleterious	ADJ
easat-284	177	43	effects	effect	NOUN
easat-284	177	44	,	,	PUNCT
easat-284	177	45	mainly	mainly	ADV
easat-284	177	46	at	at	ADP
easat-284	177	47	alveolo	alveolo	ADV
easat-284	177	48	-	-	PUNCT
easat-284	177	49	capillary	capillary	ADJ
easat-284	177	50	level	level	NOUN
easat-284	177	51	[	[	X
easat-284	177	52	46	46	NUM
easat-284	177	53	]	]	SYM
easat-284	177	54	•	•	NUM
easat-284	177	55	serping1	serping1	NOUN
easat-284	177	56	counteracts	counteract	VERB
easat-284	177	57	platelet	platelet	NOUN
easat-284	177	58	activation	activation	NOUN
easat-284	177	59	activity	activity	NOUN
easat-284	177	60	on	on	ADP
easat-284	177	61	clotting	clotting	NOUN
easat-284	177	62	and	and	CCONJ
easat-284	177	63	complement	complement	NOUN
easat-284	177	64	cascade45	cascade45	NOUN
easat-284	177	65	and	and	CCONJ
easat-284	177	66	pselectin	pselectin	NOUN
easat-284	177	67	/	/	SYM
easat-284	177	68	hgmb1	hgmb1	NOUN
easat-284	177	69	expression	expression	NOUN
easat-284	178	1	[	[	X
easat-284	178	2	13	13	NUM
easat-284	178	3	,	,	PUNCT
easat-284	178	4	38	38	NUM
easat-284	178	5	]	]	SYM
easat-284	178	6	•	•	NOUN
easat-284	178	7	other	other	ADJ
easat-284	178	8	aspecific	aspecific	ADJ
easat-284	178	9	inhibitors	inhibitor	NOUN
easat-284	178	10	like	like	ADP
easat-284	178	11	alfa2	alfa2	NOUN
easat-284	178	12	macroglobulin	macroglobulin	PROPN
easat-284	178	13	and	and	CCONJ
easat-284	178	14	thrombomodulin	thrombomodulin	PROPN
easat-284	178	15	•	•	ADP
easat-284	178	16	cp	cp	PROPN
easat-284	178	17	nabs	nab	NOUN
easat-284	178	18	boost	boost	VERB
easat-284	178	19	a	a	DET
easat-284	178	20	much	much	ADV
easat-284	178	21	stronger	strong	ADJ
easat-284	178	22	immune	immune	ADJ
easat-284	178	23	response	response	NOUN
easat-284	178	24	of	of	ADP
easat-284	178	25	newly	newly	ADV
easat-284	178	26	dendritic	dendritic	ADJ
easat-284	178	27	cells	cell	NOUN
easat-284	178	28	inf	inf	NOUN
easat-284	178	29	-	-	PUNCT
easat-284	178	30	cdc2	cdc2	NOUN
easat-284	178	31	[	[	X
easat-284	178	32	55	55	NUM
easat-284	178	33	]	]	PUNCT
easat-284	178	34	.	.	PUNCT
easat-284	179	1	the	the	DET
easat-284	179	2	nsp5	nsp5	ADJ
easat-284	179	3	main	main	ADJ
easat-284	179	4	protease	protease	NOUN
easat-284	179	5	(	(	PUNCT
easat-284	179	6	mpro	mpro	ADJ
easat-284	179	7	,	,	PUNCT
easat-284	179	8	3c	3c	NUM
easat-284	179	9	)	)	PUNCT
easat-284	179	10	is	be	AUX
easat-284	179	11	investigated	investigate	VERB
easat-284	179	12	as	as	ADP
easat-284	179	13	a	a	DET
easat-284	179	14	potential	potential	ADJ
easat-284	179	15	drug	drug	NOUN
easat-284	179	16	target	target	NOUN
easat-284	179	17	because	because	SCONJ
easat-284	179	18	of	of	ADP
easat-284	179	19	its	its	PRON
easat-284	179	20	involvement	involvement	NOUN
easat-284	179	21	in	in	ADP
easat-284	179	22	processing	process	VERB
easat-284	179	23	the	the	DET
easat-284	179	24	proteins	protein	NOUN
easat-284	179	25	coded	code	VERB
easat-284	179	26	from	from	ADP
easat-284	179	27	viral	viral	ADJ
easat-284	179	28	rna	rna	NOUN
easat-284	180	1	[	[	X
easat-284	180	2	56	56	NUM
easat-284	180	3	]	]	PUNCT
easat-284	180	4	.	.	PUNCT
easat-284	181	1	aprotinin	aprotinin	PROPN
easat-284	181	2	can	can	AUX
easat-284	181	3	be	be	AUX
easat-284	181	4	used	use	VERB
easat-284	181	5	as	as	ADP
easat-284	181	6	a	a	DET
easat-284	181	7	treatment	treatment	NOUN
easat-284	181	8	startegy	startegy	NOUN
easat-284	181	9	to	to	PART
easat-284	181	10	support	support	VERB
easat-284	181	11	serine	serine	NOUN
easat-284	181	12	proteases	protease	NOUN
easat-284	181	13	activators	activator	NOUN
easat-284	181	14	/	/	SYM
easat-284	181	15	inhibitors	inhibitor	NOUN
easat-284	181	16	balance	balance	NOUN
easat-284	181	17	.	.	PUNCT
easat-284	182	1	2	2	X
easat-284	182	2	.	.	X
easat-284	182	3	discussion	discussion	NOUN
easat-284	182	4	the	the	DET
easat-284	182	5	sars	sar	NOUN
easat-284	182	6	-	-	PUNCT
easat-284	182	7	cov-2	cov-2	PART
easat-284	182	8	infection	infection	NOUN
easat-284	182	9	is	be	AUX
easat-284	182	10	a	a	DET
easat-284	182	11	protease	protease	NOUN
easat-284	182	12	dependent	dependent	ADJ
easat-284	182	13	process	process	NOUN
easat-284	182	14	as	as	ADP
easat-284	182	15	cell	cell	NOUN
easat-284	182	16	entry	entry	NOUN
easat-284	182	17	depends	depend	VERB
easat-284	182	18	on	on	ADP
easat-284	182	19	the	the	DET
easat-284	182	20	binding	binding	NOUN
easat-284	182	21	of	of	ADP
easat-284	182	22	the	the	DET
easat-284	182	23	spike	spike	ADJ
easat-284	182	24	protein	protein	NOUN
easat-284	182	25	’s	’s	PART
easat-284	182	26	s1	s1	NOUN
easat-284	182	27	subunit	subunit	NOUN
easat-284	182	28	to	to	PART
easat-284	182	29	ace2	ace2	VERB
easat-284	182	30	on	on	ADP
easat-284	182	31	the	the	DET
easat-284	182	32	target	target	NOUN
easat-284	182	33	cell	cell	NOUN
easat-284	182	34	surface	surface	NOUN
easat-284	182	35	and	and	CCONJ
easat-284	182	36	host	host	NOUN
easat-284	182	37	proteases	protease	NOUN
easat-284	182	38	,	,	PUNCT
easat-284	182	39	furin	furin	NOUN
easat-284	182	40	,	,	PUNCT
easat-284	182	41	as	as	ADV
easat-284	182	42	well	well	ADV
easat-284	182	43	as	as	ADP
easat-284	182	44	tmprss2	tmprss2	VERB
easat-284	182	45	processes	process	VERB
easat-284	182	46	the	the	DET
easat-284	182	47	s	s	NOUN
easat-284	182	48	protein	protein	NOUN
easat-284	182	49	to	to	PART
easat-284	182	50	facilitate	facilitate	VERB
easat-284	182	51	membra	membra	NOUN
easat-284	182	52	ne	ne	NOUN
easat-284	182	53	fusion	fusion	NOUN
easat-284	182	54	,	,	PUNCT
easat-284	182	55	allowing	allow	VERB
easat-284	182	56	sars	sar	NOUN
easat-284	182	57	-	-	PUNCT
easat-284	182	58	cov-2	cov-2	NOUN
easat-284	182	59	to	to	PART
easat-284	182	60	have	have	AUX
easat-284	182	61	enhanced	enhance	VERB
easat-284	182	62	proteolytic	proteolytic	ADJ
easat-284	182	63	activation	activation	NOUN
easat-284	182	64	in	in	ADP
easat-284	182	65	a	a	DET
easat-284	182	66	wider	wide	ADJ
easat-284	182	67	range	range	NOUN
easat-284	182	68	of	of	ADP
easat-284	182	69	tissues	tissue	NOUN
easat-284	182	70	[	[	X
easat-284	182	71	3	3	NUM
easat-284	182	72	]	]	PUNCT
easat-284	182	73	.	.	PUNCT
easat-284	183	1	aprotinin	aprotinin	PROPN
easat-284	183	2	have	have	AUX
easat-284	183	3	been	be	AUX
easat-284	183	4	shown	show	VERB
easat-284	183	5	to	to	PART
easat-284	183	6	inhibit	inhibit	VERB
easat-284	183	7	sars	sar	NOUN
easat-284	183	8	-	-	PUNCT
easat-284	183	9	cov-2	cov-2	NOUN
easat-284	183	10	entry	entry	NOUN
easat-284	183	11	and	and	CCONJ
easat-284	183	12	replication	replication	NOUN
easat-284	183	13	and	and	CCONJ
easat-284	183	14	thus	thus	ADV
easat-284	183	15	an	an	DET
easat-284	183	16	aerosol	aerosol	NOUN
easat-284	183	17	treatment	treatment	NOUN
easat-284	183	18	as	as	ADP
easat-284	183	19	for	for	ADP
easat-284	183	20	influenza	influenza	NOUN
easat-284	183	21	is	be	AUX
easat-284	183	22	suggested	suggest	VERB
easat-284	183	23	.	.	PUNCT
easat-284	184	1	after	after	ADP
easat-284	184	2	cell	cell	NOUN
easat-284	184	3	entry	entry	NOUN
easat-284	184	4	,	,	PUNCT
easat-284	184	5	sars	sar	NOUN
easat-284	184	6	-	-	PUNCT
easat-284	184	7	cov-2	cov-2	PART
easat-284	184	8	induces	induce	VERB
easat-284	184	9	a	a	DET
easat-284	184	10	profound	profound	ADJ
easat-284	184	11	immunological	immunological	ADJ
easat-284	184	12	unbalance	unbalance	NOUN
easat-284	184	13	,	,	PUNCT
easat-284	184	14	with	with	ADP
easat-284	184	15	a	a	DET
easat-284	184	16	delay	delay	NOUN
easat-284	184	17	of	of	ADP
easat-284	184	18	the	the	DET
easat-284	184	19	ifn	ifn	PROPN
easat-284	184	20	-	-	PUNCT
easat-284	184	21	i	i	PRON
easat-284	184	22	and	and	CCONJ
easat-284	184	23	-iii	-iii	VERB
easat-284	184	24	response	response	NOUN
easat-284	184	25	and	and	CCONJ
easat-284	184	26	upregulation	upregulation	NOUN
easat-284	184	27	of	of	ADP
easat-284	184	28	chemoattractants	chemoattractant	NOUN
easat-284	184	29	for	for	ADP
easat-284	184	30	neutrophils	neutrophil	NOUN
easat-284	184	31	and	and	CCONJ
easat-284	184	32	monocytes	monocyte	NOUN
easat-284	184	33	,	,	PUNCT
easat-284	184	34	cytokines	cytokine	VERB
easat-284	184	35	storm	storm	NOUN
easat-284	184	36	and	and	CCONJ
easat-284	184	37	increased	increase	VERB
easat-284	184	38	reactants	reactant	NOUN
easat-284	184	39	biomarkers	biomarker	NOUN
easat-284	184	40	.	.	PUNCT
easat-284	185	1	a	a	DET
easat-284	185	2	panoptosis	panoptosis	NOUN
easat-284	185	3	process	process	NOUN
easat-284	185	4	is	be	AUX
easat-284	185	5	caused	cause	VERB
easat-284	185	6	by	by	ADP
easat-284	185	7	the	the	DET
easat-284	185	8	combination	combination	NOUN
easat-284	185	9	of	of	ADP
easat-284	185	10	tnf	tnf	PROPN
easat-284	185	11	-	-	PUNCT
easat-284	185	12	α	α	PROPN
easat-284	185	13	and	and	CCONJ
easat-284	185	14	ifn	ifn	PROPN
easat-284	185	15	-	-	PUNCT
easat-284	185	16	γ	γ	PROPN
easat-284	185	17	.	.	PROPN
easat-284	185	18	chemoattractants	chemoattractant	NOUN
easat-284	185	19	and	and	CCONJ
easat-284	185	20	cytokines	cytokine	NOUN
easat-284	185	21	enhance	enhance	VERB
easat-284	185	22	recruitment	recruitment	NOUN
easat-284	185	23	of	of	ADP
easat-284	185	24	neutrophils	neutrophil	NOUN
easat-284	185	25	,	,	PUNCT
easat-284	185	26	while	while	SCONJ
easat-284	185	27	suppressing	suppress	VERB
easat-284	185	28	lymphocytes	lymphocyte	VERB
easat-284	185	29	with	with	ADP
easat-284	185	30	an	an	DET
easat-284	185	31	increase	increase	NOUN
easat-284	185	32	of	of	ADP
easat-284	185	33	nlr	nlr	PROPN
easat-284	185	34	,	,	PUNCT
easat-284	185	35	which	which	PRON
easat-284	185	36	is	be	AUX
easat-284	185	37	considered	consider	VERB
easat-284	185	38	a	a	DET
easat-284	185	39	marker	marker	NOUN
easat-284	185	40	of	of	ADP
easat-284	185	41	severe	severe	ADJ
easat-284	185	42	covid	covid	PROPN
easat-284	185	43	-19	-19	PROPN
easat-284	185	44	.	.	PUNCT
easat-284	186	1	neutrophils	neutrophil	NOUN
easat-284	186	2	,	,	PUNCT
easat-284	186	3	together	together	ADV
easat-284	186	4	with	with	ADP
easat-284	186	5	other	other	ADJ
easat-284	186	6	mononuclear	mononuclear	ADJ
easat-284	186	7	,	,	PUNCT
easat-284	186	8	migrate	migrate	VERB
easat-284	186	9	to	to	ADP
easat-284	186	10	the	the	DET
easat-284	186	11	infected	infected	ADJ
easat-284	186	12	alveoli	alveolus	NOUN
easat-284	186	13	,	,	PUNCT
easat-284	186	14	where	where	SCONJ
easat-284	186	15	they	they	PRON
easat-284	186	16	attack	attack	VERB
easat-284	186	17	sars	sar	NOUN
easat-284	186	18	-	-	PUNCT
easat-284	186	19	cov-2	cov-2	NOUN
easat-284	186	20	,	,	PUNCT
easat-284	186	21	but	but	CCONJ
easat-284	186	22	in	in	ADP
easat-284	186	23	addition	addition	NOUN
easat-284	186	24	to	to	ADP
easat-284	186	25	direct	direct	ADJ
easat-284	186	26	virus	virus	NOUN
easat-284	186	27	-	-	PUNCT
easat-284	186	28	inflicted	inflict	VERB
easat-284	186	29	pathologies	pathology	NOUN
easat-284	186	30	,	,	PUNCT
easat-284	186	31	their	their	PRON
easat-284	186	32	exaggerated	exaggerated	ADJ
easat-284	186	33	“	"	PUNCT
easat-284	186	34	unfriendly	unfriendly	ADJ
easat-284	186	35	fire	fire	NOUN
easat-284	186	36	”	"	PUNCT
easat-284	186	37	responses	response	NOUN
easat-284	186	38	,	,	PUNCT
easat-284	186	39	resulting	result	VERB
easat-284	186	40	in	in	ADP
easat-284	186	41	a	a	DET
easat-284	186	42	“	"	PUNCT
easat-284	186	43	proteolytic	proteolytic	ADJ
easat-284	186	44	storm	storm	NOUN
easat-284	186	45	”	"	PUNCT
easat-284	186	46	and	and	CCONJ
easat-284	186	47	,	,	PUNCT
easat-284	186	48	inducing	induce	VERB
easat-284	186	49	alveolar	alveolar	ADJ
easat-284	186	50	capillary	capillary	ADJ
easat-284	186	51	endotheliopathy	endotheliopathy	NOUN
easat-284	186	52	,	,	PUNCT
easat-284	186	53	contribute	contribute	VERB
easat-284	186	54	to	to	ADP
easat-284	186	55	disease	disease	NOUN
easat-284	186	56	severity	severity	NOUN
easat-284	186	57	and	and	CCONJ
easat-284	186	58	subsequent	subsequent	ADJ
easat-284	186	59	viral	viral	ADJ
easat-284	186	60	dissemination	dissemination	NOUN
easat-284	186	61	.	.	PUNCT
easat-284	187	1	one	one	NUM
easat-284	187	2	of	of	ADP
easat-284	187	3	the	the	DET
easat-284	187	4	mechanisms	mechanism	NOUN
easat-284	187	5	that	that	PRON
easat-284	187	6	neutrophils	neutrophil	NOUN
easat-284	187	7	undertake	undertake	VERB
easat-284	187	8	for	for	ADP
easat-284	187	9	host	host	NOUN
easat-284	187	10	defense	defense	NOUN
easat-284	187	11	is	be	AUX
easat-284	187	12	nets	net	NOUN
easat-284	187	13	release	release	NOUN
easat-284	187	14	,	,	PUNCT
easat-284	187	15	known	know	VERB
easat-284	187	16	as	as	ADP
easat-284	187	17	netosis	netosis	NOUN
easat-284	187	18	.	.	PUNCT
easat-284	188	1	nets	net	NOUN
easat-284	188	2	,	,	PUNCT
easat-284	188	3	via	via	ADP
easat-284	188	4	electrostatic	electrostatic	ADJ
easat-284	188	5	interactions	interaction	NOUN
easat-284	188	6	,	,	PUNCT
easat-284	188	7	activate	activate	VERB
easat-284	188	8	the	the	DET
easat-284	188	9	contact	contact	NOUN
easat-284	188	10	pathway	pathway	NOUN
easat-284	188	11	of	of	ADP
easat-284	188	12	coagulation	coagulation	NOUN
easat-284	188	13	and	and	CCONJ
easat-284	188	14	,	,	PUNCT
easat-284	188	15	through	through	ADP
easat-284	188	16	tissue	tissue	NOUN
easat-284	188	17	factor	factor	NOUN
easat-284	188	18	,	,	PUNCT
easat-284	188	19	the	the	DET
easat-284	188	20	intrinsic	intrinsic	ADJ
easat-284	188	21	pathway	pathway	NOUN
easat-284	188	22	and	and	CCONJ
easat-284	188	23	form	form	VERB
easat-284	188	24	a	a	DET
easat-284	188	25	scaffold	scaffold	NOUN
easat-284	188	26	for	for	ADP
easat-284	188	27	thrombus	thrombus	NOUN
easat-284	188	28	formation	formation	NOUN
easat-284	188	29	by	by	ADP
easat-284	188	30	promoting	promote	VERB
easat-284	188	31	platelet	platelet	NOUN
easat-284	188	32	adhesion	adhesion	NOUN
easat-284	188	33	and	and	CCONJ
easat-284	188	34	by	by	ADP
easat-284	188	35	concentrating	concentrate	VERB
easat-284	188	36	coagulation	coagulation	NOUN
easat-284	188	37	factors	factor	NOUN
easat-284	188	38	involved	involve	VERB
easat-284	188	39	in	in	ADP
easat-284	188	40	clotting	clotting	NOUN
easat-284	188	41	.	.	PUNCT
easat-284	189	1	concurrently	concurrently	ADV
easat-284	189	2	sars	sar	NOUN
easat-284	189	3	-	-	PUNCT
easat-284	189	4	cov-2	cov-2	NOUN
easat-284	189	5	,	,	PUNCT
easat-284	189	6	together	together	ADV
easat-284	189	7	with	with	ADP
easat-284	189	8	neutrophil	neutrophil	ADJ
easat-284	189	9	elastase	elastase	NOUN
easat-284	189	10	and	and	CCONJ
easat-284	189	11	other	other	ADJ
easat-284	189	12	proteases	protease	NOUN
easat-284	189	13	,	,	PUNCT
easat-284	189	14	induces	induce	VERB
easat-284	189	15	endothelial	endothelial	ADJ
easat-284	189	16	cells	cell	NOUN
easat-284	189	17	damage	damage	NOUN
easat-284	189	18	(	(	PUNCT
easat-284	189	19	endotheliopathy	endotheliopathy	ADJ
easat-284	189	20	)	)	PUNCT
easat-284	189	21	triggering	trigger	VERB
easat-284	189	22	the	the	DET
easat-284	189	23	activation	activation	NOUN
easat-284	189	24	of	of	ADP
easat-284	189	25	two	two	NUM
easat-284	189	26	independent	independent	ADJ
easat-284	189	27	endothelial	endothelial	ADJ
easat-284	189	28	pathways	pathway	NOUN
easat-284	189	29	and	and	CCONJ
easat-284	189	30	activation	activation	NOUN
easat-284	189	31	of	of	ADP
easat-284	189	32	the	the	DET
easat-284	189	33	platelet	platelet	NOUN
easat-284	189	34	and	and	CCONJ
easat-284	189	35	endothelial	endothelial	ADJ
easat-284	189	36	exocytosis	exocytosis	NOUN
easat-284	189	37	of	of	ADP
easat-284	189	38	ulvwf	ulvwf	NOUN
easat-284	189	39	(	(	PUNCT
easat-284	189	40	due	due	ADP
easat-284	189	41	to	to	ADP
easat-284	189	42	adamts13	adamts13	NOUN
easat-284	189	43	biosynthesis	biosynthesis	NOUN
easat-284	189	44	inhibition	inhibition	NOUN
easat-284	189	45	)	)	PUNCT
easat-284	189	46	,	,	PUNCT
easat-284	189	47	mediating	mediate	VERB
easat-284	189	48	microthrombogenesis	microthrombogenesis	NOUN
easat-284	189	49	and	and	CCONJ
easat-284	189	50	hypercoagulability	hypercoagulability	NOUN
easat-284	189	51	state	state	NOUN
easat-284	189	52	.	.	PUNCT
easat-284	190	1	the	the	DET
easat-284	190	2	activation	activation	NOUN
easat-284	190	3	of	of	ADP
easat-284	190	4	platelets	platelet	NOUN
easat-284	190	5	an	an	DET
easat-284	190	6	d	d	NOUN
easat-284	190	7	clotting	clot	VERB
easat-284	190	8	proteolytic	proteolytic	ADJ
easat-284	190	9	system	system	NOUN
easat-284	190	10	involves	involve	VERB
easat-284	190	11	the	the	DET
easat-284	190	12	other	other	ADJ
easat-284	190	13	innate	innate	ADJ
easat-284	190	14	serine	serine	NOUN
easat-284	190	15	protease	protease	NOUN
easat-284	190	16	systems	system	NOUN
easat-284	190	17	with	with	ADP
easat-284	190	18	their	their	PRON
easat-284	190	19	four	four	NUM
easat-284	190	20	major	major	ADJ
easat-284	190	21	columns	column	NOUN
easat-284	190	22	,	,	PUNCT
easat-284	190	23	coagulation	coagulation	NOUN
easat-284	190	24	,	,	PUNCT
easat-284	190	25	fibrinolysis	fibrinolysis	NOUN
easat-284	190	26	,	,	PUNCT
easat-284	190	27	kallikrein	kallikrein	ADJ
easat-284	190	28	and	and	CCONJ
easat-284	190	29	complement	complement	NOUN
easat-284	190	30	,	,	PUNCT
easat-284	190	31	strictly	strictly	ADV
easat-284	190	32	correlated	correlate	VERB
easat-284	190	33	and	and	CCONJ
easat-284	190	34	interconnected	interconnect	VERB
easat-284	190	35	and	and	CCONJ
easat-284	190	36	their	their	PRON
easat-284	190	37	physiological	physiological	ADJ
easat-284	190	38	maintenance	maintenance	NOUN
easat-284	190	39	is	be	AUX
easat-284	190	40	the	the	DET
easat-284	190	41	result	result	NOUN
easat-284	190	42	of	of	ADP
easat-284	190	43	a	a	DET
easat-284	190	44	rigorous	rigorous	ADJ
easat-284	190	45	balance	balance	NOUN
easat-284	190	46	between	between	ADP
easat-284	190	47	activators	activator	NOUN
easat-284	190	48	and	and	CCONJ
easat-284	190	49	inhibitors	inhibitor	NOUN
easat-284	190	50	.	.	PUNCT
easat-284	191	1	the	the	DET
easat-284	191	2	interplay	interplay	NOUN
easat-284	191	3	between	between	ADP
easat-284	191	4	complement	complement	NOUN
easat-284	191	5	and	and	CCONJ
easat-284	191	6	coagulation	coagulation	NOUN
easat-284	191	7	is	be	AUX
easat-284	191	8	crucial	crucial	ADJ
easat-284	191	9	to	to	PART
easat-284	191	10	understand	understand	VERB
easat-284	191	11	the	the	DET
easat-284	191	12	clinical	clinical	ADJ
easat-284	191	13	implications	implication	NOUN
easat-284	191	14	in	in	ADP
easat-284	191	15	covid	covid	PROPN
easat-284	191	16	-19	-19	PROPN
easat-284	191	17	.	.	PUNCT
easat-284	192	1	nets	net	NOUN
easat-284	192	2	activate	activate	VERB
easat-284	192	3	kallikrein	kallikrein	NOUN
easat-284	192	4	/	/	SYM
easat-284	192	5	kinin	kinin	ADJ
easat-284	192	6	,	,	PUNCT
easat-284	192	7	inducing	induce	VERB
easat-284	192	8	a	a	DET
easat-284	192	9	prothrombotic	prothrombotic	ADJ
easat-284	192	10	state	state	NOUN
easat-284	192	11	by	by	ADP
easat-284	192	12	activating	activate	VERB
easat-284	192	13	intrinsic	intrinsic	ADJ
easat-284	192	14	pathway	pathway	NOUN
easat-284	192	15	and	and	CCONJ
easat-284	192	16	proinflammatory	proinflammatory	ADJ
easat-284	192	17	state	state	NOUN
easat-284	192	18	by	by	ADP
easat-284	192	19	producing	produce	VERB
easat-284	192	20	bioactive	bioactive	NOUN
easat-284	192	21	peptide	peptide	NOUN
easat-284	192	22	bradykinin	bradykinin	PROPN
easat-284	192	23	.	.	PUNCT
easat-284	193	1	main	main	ADJ
easat-284	193	2	family	family	NOUN
easat-284	193	3	of	of	ADP
easat-284	193	4	the	the	DET
easat-284	193	5	serine	serine	NOUN
easat-284	193	6	protease	protease	NOUN
easat-284	193	7	inhibitors	inhibitor	NOUN
easat-284	193	8	(	(	PUNCT
easat-284	193	9	serpins	serpin	NOUN
easat-284	193	10	)	)	PUNCT
easat-284	193	11	formed	form	VERB
easat-284	193	12	by	by	ADP
easat-284	193	13	serpina1	serpina1	PROPN
easat-284	193	14	,	,	PUNCT
easat-284	193	15	serpina5	serpina5	NOUN
easat-284	193	16	,	,	PUNCT
easat-284	193	17	serpinc1	serpinc1	NOUN
easat-284	193	18	,	,	PUNCT
easat-284	193	19	serpind	serpind	NOUN
easat-284	193	20	,	,	PUNCT
easat-284	193	21	serpine1	serpine1	PROPN
easat-284	193	22	,	,	PUNCT
easat-284	193	23	serping1	serping1	NOUN
easat-284	193	24	and	and	CCONJ
easat-284	193	25	serpinf2	serpinf2	NOUN
easat-284	193	26	inhibit	inhibit	VERB
easat-284	193	27	the	the	DET
easat-284	193	28	major	major	ADJ
easat-284	193	29	serine	serine	NOUN
easat-284	193	30	protease	protease	NOUN
easat-284	193	31	cascades	cascade	NOUN
easat-284	193	32	.	.	PUNCT
easat-284	194	1	complement	complement	NOUN
easat-284	194	2	activation	activation	NOUN
easat-284	194	3	is	be	AUX
easat-284	194	4	in	in	ADP
easat-284	194	5	hibited	hibite	VERB
easat-284	194	6	also	also	ADV
easat-284	194	7	by	by	ADP
easat-284	194	8	decay	decay	NOUN
easat-284	194	9	-	-	PUNCT
easat-284	194	10	accelerating	accelerate	VERB
easat-284	194	11	factor	factor	NOUN
easat-284	194	12	(	(	PUNCT
easat-284	194	13	daf	daf	NOUN
easat-284	194	14	)	)	PUNCT
easat-284	194	15	and	and	CCONJ
easat-284	194	16	factor	factor	NOUN
easat-284	194	17	h	h	NOUN
easat-284	194	18	(	(	PUNCT
easat-284	194	19	alternative	alternative	ADJ
easat-284	194	20	pathway	pathway	NOUN
easat-284	194	21	)	)	PUNCT
easat-284	194	22	.	.	PUNCT
easat-284	195	1	alpha	alpha	NOUN
easat-284	195	2	2	2	NUM
easat-284	195	3	macroglobulin	macroglobulin	PROPN
easat-284	195	4	acts	act	VERB
easat-284	195	5	as	as	ADP
easat-284	195	6	an	an	DET
easat-284	195	7	antiprotease	antiprotease	NOUN
easat-284	195	8	for	for	ADP
easat-284	195	9	a	a	DET
easat-284	195	10	variety	variety	NOUN
easat-284	195	11	of	of	ADP
easat-284	195	12	proteases	protease	NOUN
easat-284	195	13	like	like	ADP
easat-284	195	14	plasmin	plasmin	NOUN
easat-284	195	15	,	,	PUNCT
easat-284	195	16	kallikrein	kallikrein	ADJ
easat-284	195	17	and	and	CCONJ
easat-284	195	18	thrombin	thrombin	NOUN
easat-284	195	19	.	.	PUNCT
easat-284	196	1	a	a	DET
easat-284	196	2	delicate	delicate	ADJ
easat-284	196	3	balance	balance	NOUN
easat-284	196	4	between	between	ADP
easat-284	196	5	serine	serine	NOUN
easat-284	196	6	proteases	protease	NOUN
easat-284	196	7	and	and	CCONJ
easat-284	196	8	their	their	PRON
easat-284	196	9	serpin	serpin	NOUN
easat-284	196	10	inhibitors	inhibitor	NOUN
easat-284	196	11	is	be	AUX
easat-284	196	12	crucial	crucial	ADJ
easat-284	196	13	for	for	ADP
easat-284	196	14	normal	normal	ADJ
easat-284	196	15	functioning	functioning	NOUN
easat-284	196	16	of	of	ADP
easat-284	196	17	biological	biological	ADJ
easat-284	196	18	pathways	pathway	NOUN
easat-284	196	19	.	.	PUNCT
easat-284	197	1	proteases	protease	NOUN
easat-284	197	2	/	/	SYM
easat-284	197	3	antiproteases	antiprotease	NOUN
easat-284	197	4	balance	balance	NOUN
easat-284	197	5	is	be	AUX
easat-284	197	6	present	present	ADJ
easat-284	197	7	also	also	ADV
easat-284	197	8	at	at	ADP
easat-284	197	9	the	the	DET
easat-284	197	10	endothelial	endothelial	ADJ
easat-284	197	11	sur	sur	NOUN
easat-284	197	12	face	face	NOUN
easat-284	197	13	(	(	PUNCT
easat-284	197	14	thrombomodulin	thrombomodulin	NOUN
easat-284	197	15	induces	induce	VERB
easat-284	197	16	protein	protein	NOUN
easat-284	197	17	c	c	NOUN
easat-284	197	18	activation	activation	NOUN
easat-284	197	19	to	to	PART
easat-284	197	20	suppress	suppress	VERB
easat-284	197	21	blood	blood	NOUN
easat-284	197	22	coagulation	coagulation	NOUN
easat-284	197	23	)	)	PUNCT
easat-284	197	24	and	and	CCONJ
easat-284	197	25	also	also	ADV
easat-284	197	26	at	at	ADP
easat-284	197	27	alveolar	alveolar	ADJ
easat-284	197	28	space	space	NOUN
easat-284	197	29	,	,	PUNCT
easat-284	197	30	where	where	SCONJ
easat-284	197	31	s	s	AUX
easat-284	197	32	erpina1	erpina1	NOUN
easat-284	197	33	strongly	strongly	ADV
easat-284	197	34	and	and	CCONJ
easat-284	197	35	specifically	specifically	ADV
easat-284	197	36	inhibits	inhibit	VERB
easat-284	197	37	neutrophil	neutrophil	ADJ
easat-284	197	38	elastase	elastase	NOUN
easat-284	197	39	.	.	PUNCT
easat-284	198	1	when	when	SCONJ
easat-284	198	2	the	the	DET
easat-284	198	3	inhibitor	inhibitor	NOUN
easat-284	198	4	concentration	concentration	NOUN
easat-284	198	5	is	be	AUX
easat-284	198	6	sufficient	sufficient	ADJ
easat-284	198	7	to	to	PART
easat-284	198	8	block	block	VERB
easat-284	198	9	released	release	VERB
easat-284	198	10	elastase	elastase	NOUN
easat-284	198	11	,	,	PUNCT
easat-284	198	12	no	no	DET
easat-284	198	13	lesion	lesion	NOUN
easat-284	198	14	happens	happen	VERB
easat-284	198	15	nor	nor	CCONJ
easat-284	198	16	in	in	ADP
easat-284	198	17	alveolar	alveolar	ADJ
easat-284	198	18	epithelium	epithelium	NOUN
easat-284	198	19	nor	nor	CCONJ
easat-284	198	20	i	i	PRON
easat-284	198	21	n	n	PRON
easat-284	198	22	alveolar	alveolar	ADJ
easat-284	198	23	endothelial	endothelial	NOUN
easat-284	198	24	wall	wall	NOUN
easat-284	198	25	and	and	CCONJ
easat-284	198	26	this	this	PRON
easat-284	198	27	corresponds	correspond	VERB
easat-284	198	28	with	with	ADP
easat-284	198	29	the	the	DET
easat-284	198	30	moderate	moderate	ADJ
easat-284	198	31	covid-19	covid-19	PROPN
easat-284	198	32	clinical	clinical	ADJ
easat-284	198	33	condition	condition	NOUN
easat-284	198	34	.	.	PUNCT
easat-284	199	1	if	if	SCONJ
easat-284	199	2	serpina1	serpina1	PROPN
easat-284	199	3	is	be	AUX
easat-284	199	4	overhelmed	overhelme	VERB
easat-284	199	5	or	or	CCONJ
easat-284	199	6	is	be	AUX
easat-284	199	7	absent	absent	ADJ
easat-284	199	8	/	/	SYM
easat-284	199	9	deficient	deficient	ADJ
easat-284	199	10	imbalance	imbalance	NOUN
easat-284	199	11	between	between	ADP
easat-284	199	12	elastase	elastase	NOUN
easat-284	199	13	and	and	CCONJ
easat-284	199	14	anti	anti	ADJ
easat-284	199	15	-	-	ADJ
easat-284	199	16	elastase	elastase	ADJ
easat-284	199	17	activity	activity	NOUN
easat-284	199	18	causes	cause	VERB
easat-284	199	19	progressive	progressive	ADJ
easat-284	199	20	damage	damage	NOUN
easat-284	199	21	of	of	ADP
easat-284	199	22	alveoli	alveoli	NOUN
easat-284	199	23	and	and	CCONJ
easat-284	199	24	endothelium	endothelium	NOUN
easat-284	199	25	,	,	PUNCT
easat-284	199	26	inducing	induce	VERB
easat-284	199	27	endotheliopathy	endotheliopathy	ADJ
easat-284	199	28	and	and	CCONJ
easat-284	199	29	thrombogenic	thrombogenic	ADJ
easat-284	199	30	state	state	NOUN
easat-284	199	31	previously	previously	ADV
easat-284	199	32	described	describe	VERB
easat-284	199	33	.	.	PUNCT
easat-284	200	1	convalescent	convalescent	NOUN
easat-284	200	2	plasma	plasma	NOUN
easat-284	200	3	has	have	AUX
easat-284	200	4	been	be	AUX
easat-284	200	5	recently	recently	ADV
easat-284	200	6	shown	show	VERB
easat-284	200	7	uneffective	uneffective	ADJ
easat-284	200	8	in	in	ADP
easat-284	200	9	several	several	ADJ
easat-284	200	10	clinical	clinical	ADJ
easat-284	200	11	trials	trial	NOUN
easat-284	200	12	with	with	ADP
easat-284	200	13	no	no	DET
easat-284	200	14	significant	significant	ADJ
easat-284	200	15	differences	difference	NOUN
easat-284	200	16	observed	observe	VERB
easat-284	200	17	in	in	ADP
easat-284	200	18	clinical	clinical	ADJ
easat-284	200	19	status	status	NOUN
easat-284	200	20	or	or	CCONJ
easat-284	200	21	overall	overall	ADJ
easat-284	200	22	mortality	mortality	NOUN
easat-284	200	23	between	between	ADP
easat-284	200	24	patients	patient	NOUN
easat-284	200	25	treated	treat	VERB
easat-284	200	26	wit	wit	ADJ
easat-284	200	27	h	h	NOUN
easat-284	200	28	convalescent	convalescent	NOUN
easat-284	200	29	plasma	plasma	NOUN
easat-284	200	30	and	and	CCONJ
easat-284	200	31	those	those	PRON
easat-284	200	32	who	who	PRON
easat-284	200	33	received	receive	VERB
easat-284	200	34	placebo	placebo	NOUN
easat-284	200	35	.	.	PUNCT
easat-284	201	1	all	all	DET
easat-284	201	2	these	these	DET
easat-284	201	3	studies	study	NOUN
easat-284	201	4	were	be	AUX
easat-284	201	5	using	use	VERB
easat-284	201	6	not	not	PART
easat-284	201	7	more	more	ADJ
easat-284	201	8	than	than	ADP
easat-284	201	9	500	500	NUM
easat-284	201	10	ml	ml	NOUN
easat-284	201	11	of	of	ADP
easat-284	201	12	convalescent	convalescent	NOUN
easat-284	201	13	plasma	plasma	NOUN
easat-284	201	14	and	and	CCONJ
easat-284	201	15	the	the	DET
easat-284	201	16	scientific	scientific	ADJ
easat-284	201	17	reason	reason	NOUN
easat-284	201	18	for	for	ADP
easat-284	201	19	the	the	DET
easat-284	201	20	transfusion	transfusion	NOUN
easat-284	201	21	was	be	AUX
easat-284	201	22	the	the	DET
easat-284	201	23	activity	activity	NOUN
easat-284	201	24	of	of	ADP
easat-284	201	25	neutralising	neutralise	VERB
easat-284	201	26	antibodies	antibody	NOUN
easat-284	201	27	against	against	ADP
easat-284	201	28	sars	sar	NOUN
easat-284	201	29	-	-	PUNCT
easat-284	201	30	cov-2	cov-2	NOUN
easat-284	201	31	.	.	PUNCT
easat-284	202	1	in	in	ADP
easat-284	202	2	this	this	DET
easat-284	202	3	paper	paper	NOUN
easat-284	202	4	,	,	PUNCT
easat-284	202	5	on	on	ADP
easat-284	202	6	the	the	DET
easat-284	202	7	contrary	contrary	NOUN
easat-284	202	8	,	,	PUNCT
easat-284	202	9	it	it	PRON
easat-284	202	10	has	have	AUX
easat-284	202	11	been	be	AUX
easat-284	202	12	shown	show	VERB
easat-284	202	13	that	that	SCONJ
easat-284	202	14	the	the	DET
easat-284	202	15	worsening	worsening	NOUN
easat-284	202	16	of	of	ADP
easat-284	202	17	covid-19	covid-19	PROPN
easat-284	202	18	clinical	clinical	ADJ
easat-284	202	19	symptoms	symptom	NOUN
easat-284	202	20	is	be	AUX
easat-284	202	21	due	due	ADJ
easat-284	202	22	to	to	ADP
easat-284	202	23	the	the	DET
easat-284	202	24	catastrophic	catastrophic	ADJ
easat-284	202	25	“	"	PUNCT
easat-284	202	26	unfriendly	unfriendly	ADJ
easat-284	202	27	fire	fire	NOUN
easat-284	202	28	”	"	PUNCT
easat-284	202	29	of	of	ADP
easat-284	202	30	recruited	recruit	VERB
easat-284	202	31	neutrophils	neutrophil	NOUN
easat-284	202	32	,	,	PUNCT
easat-284	202	33	with	with	ADP
easat-284	202	34	over	over	ADP
easat-284	202	35	helming	helming	NOUN
easat-284	202	36	and	and	CCONJ
easat-284	202	37	imbalancing	imbalancing	NOUN
easat-284	202	38	of	of	ADP
easat-284	202	39	serine	serine	NOUN
easat-284	202	40	proteolytic	proteolytic	ADJ
easat-284	202	41	cascades	cascade	NOUN
easat-284	202	42	activator	activator	NOUN
easat-284	202	43	proteases	protease	NOUN
easat-284	202	44	over	over	ADP
easat-284	202	45	inhibitors	inhibitor	NOUN
easat-284	202	46	,	,	PUNCT
easat-284	202	47	serious	serious	ADJ
easat-284	202	48	endotheliopathy	endotheliopathy	ADJ
easat-284	202	49	,	,	PUNCT
easat-284	202	50	netosis	netosis	PROPN
easat-284	202	51	,	,	PUNCT
easat-284	202	52	ulvwf	ulvwf	NOUN
easat-284	202	53	release	release	NOUN
easat-284	202	54	,	,	PUNCT
easat-284	202	55	hypercoagulability	hypercoagulability	NOUN
easat-284	202	56	and	and	CCONJ
easat-284	202	57	diffuse	diffuse	PROPN
easat-284	202	58	micro	micro	ADJ
easat-284	202	59	/	/	SYM
easat-284	202	60	macrothrombi	macrothrombi	NOUN
easat-284	202	61	formation	formation	NOUN
easat-284	202	62	(	(	PUNCT
easat-284	202	63	proteolytic	proteolytic	ADJ
easat-284	202	64	storm	storm	NOUN
easat-284	202	65	)	)	PUNCT
easat-284	202	66	.	.	PUNCT
easat-284	203	1	thus	thus	ADV
easat-284	203	2	,	,	PUNCT
easat-284	203	3	the	the	DET
easat-284	203	4	transfusion	transfusion	NOUN
easat-284	203	5	of	of	ADP
easat-284	203	6	human	human	ADJ
easat-284	203	7	plasma	plasma	NOUN
easat-284	203	8	,	,	PUNCT
easat-284	203	9	non	non	ADJ
easat-284	203	10	-	-	ADJ
easat-284	203	11	convalescent	convalescent	ADJ
easat-284	203	12	,	,	PUNCT
easat-284	203	13	should	should	AUX
easat-284	203	14	be	be	AUX
easat-284	203	15	used	use	VERB
easat-284	203	16	in	in	ADP
easat-284	203	17	adequate	adequate	ADJ
easat-284	203	18	quantities	quantity	NOUN
easat-284	203	19	(	(	PUNCT
easat-284	203	20	more	more	ADJ
easat-284	203	21	than	than	ADP
easat-284	203	22	2	2	NUM
easat-284	203	23	liters	liter	NOUN
easat-284	203	24	and/or	and/or	CCONJ
easat-284	203	25	following	follow	VERB
easat-284	203	26	plasma	plasma	NOUN
easat-284	203	27	-	-	PUNCT
easat-284	203	28	exchange	exchange	NOUN
easat-284	203	29	procedures	procedure	NOUN
easat-284	203	30	)	)	PUNCT
easat-284	203	31	due	due	ADP
easat-284	203	32	to	to	ADP
easat-284	203	33	the	the	DET
easat-284	203	34	large	large	ADJ
easat-284	203	35	quantity	quantity	NOUN
easat-284	203	36	of	of	ADP
easat-284	203	37	protease	protease	NOUN
easat-284	203	38	inhibitors	inhibitor	NOUN
easat-284	203	39	supplied	supply	VERB
easat-284	203	40	.	.	PUNCT
easat-284	204	1	other	other	ADJ
easat-284	204	2	serine	serine	NOUN
easat-284	204	3	protease	protease	NOUN
easat-284	204	4	inhibitors	inhibitor	NOUN
easat-284	204	5	like	like	ADP
easat-284	204	6	aprotinin	aprotinin	NOUN
easat-284	204	7	can	can	AUX
easat-284	204	8	be	be	AUX
easat-284	204	9	used	use	VERB
easat-284	204	10	to	to	PART
easat-284	204	11	restore	restore	VERB
easat-284	204	12	serine	serine	NOUN
easat-284	204	13	protease	protease	NOUN
easat-284	204	14	balance	balance	NOUN
easat-284	204	15	,	,	PUNCT
easat-284	204	16	working	work	VERB
easat-284	204	17	as	as	ADP
easat-284	204	18	a	a	DET
easat-284	204	19	“	"	PUNCT
easat-284	204	20	firehose	firehose	NOUN
easat-284	204	21	”	"	PUNCT
easat-284	204	22	extinguishing	extinguish	VERB
easat-284	204	23	“	"	PUNCT
easat-284	204	24	proteolytic	proteolytic	ADJ
easat-284	204	25	storm	storm	NOUN
easat-284	204	26	”	"	PUNCT
easat-284	204	27	.	.	PUNCT
easat-284	205	1	3	3	X
easat-284	205	2	.	.	X
easat-284	205	3	conclusion	conclusion	NOUN
easat-284	205	4	sars	sar	NOUN
easat-284	205	5	-	-	PUNCT
easat-284	205	6	cov-2	cov-2	PART
easat-284	205	7	cell	cell	NOUN
easat-284	205	8	entry	entry	NOUN
easat-284	205	9	is	be	AUX
easat-284	205	10	a	a	DET
easat-284	205	11	protease	protease	NOUN
easat-284	205	12	dependent	dependent	ADJ
easat-284	205	13	process	process	NOUN
easat-284	205	14	and	and	CCONJ
easat-284	205	15	can	can	AUX
easat-284	205	16	be	be	AUX
easat-284	205	17	efficiently	efficiently	ADV
easat-284	205	18	inhibited	inhibit	VERB
easat-284	205	19	by	by	ADP
easat-284	205	20	aprotinin	aprotinin	PROPN
easat-284	205	21	,	,	PUNCT
easat-284	205	22	a	a	DET
easat-284	205	23	serine	serine	ADJ
easat-284	205	24	protease	protease	NOUN
easat-284	205	25	inhibitor	inhibitor	NOUN
easat-284	205	26	.	.	PUNCT
easat-284	206	1	severe	severe	ADJ
easat-284	206	2	covid-19	covid-19	PROPN
easat-284	206	3	is	be	AUX
easat-284	206	4	the	the	DET
easat-284	206	5	consequence	consequence	NOUN
easat-284	206	6	of	of	ADP
easat-284	206	7	neutrophils	neutrophil	NOUN
easat-284	206	8	induced	induce	VERB
easat-284	206	9	“	"	PUNCT
easat-284	206	10	proteolytic	proteolytic	ADJ
easat-284	206	11	storm	storm	NOUN
easat-284	206	12	”	"	PUNCT
easat-284	206	13	,	,	PUNCT
easat-284	206	14	with	with	ADP
easat-284	206	15	serine	serine	NOUN
easat-284	206	16	proteases	protease	NOUN
easat-284	206	17	released	release	VERB
easat-284	206	18	in	in	ADP
easat-284	206	19	large	large	ADJ
easat-284	206	20	quantit	quantit	NOUN
easat-284	206	21	ies	ie	NOUN
easat-284	206	22	able	able	ADJ
easat-284	206	23	to	to	PART
easat-284	206	24	overwhelm	overwhelm	VERB
easat-284	206	25	physiological	physiological	ADJ
easat-284	206	26	homeostasis	homeostasis	NOUN
easat-284	206	27	between	between	ADP
easat-284	206	28	activators	activator	NOUN
easat-284	206	29	and	and	CCONJ
easat-284	206	30	inhibitors	inhibitor	NOUN
easat-284	206	31	.	.	PUNCT
easat-284	207	1	cp	cp	PROPN
easat-284	207	2	transfused	transfuse	VERB
easat-284	207	3	to	to	PART
easat-284	207	4	supply	supply	VERB
easat-284	207	5	nabs	nab	NOUN
easat-284	207	6	against	against	ADP
easat-284	207	7	sars	sar	NOUN
easat-284	207	8	-cov-2	-cov-2	VERB
easat-284	207	9	in	in	ADP
easat-284	207	10	severe	severe	ADJ
easat-284	207	11	covid-19	covid-19	PROPN
easat-284	207	12	patients	patient	NOUN
easat-284	207	13	has	have	AUX
easat-284	207	14	failed	fail	VERB
easat-284	207	15	in	in	ADP
easat-284	207	16	several	several	ADJ
easat-284	207	17	clinical	clinical	ADJ
easat-284	207	18	trials	trial	NOUN
easat-284	207	19	showing	show	VERB
easat-284	207	20	no	no	DET
easat-284	207	21	significant	significant	ADJ
easat-284	207	22	differences	difference	NOUN
easat-284	207	23	in	in	ADP
easat-284	207	24	clinical	clinical	ADJ
easat-284	207	25	status	status	NOUN
easat-284	207	26	or	or	CCONJ
easat-284	207	27	ov	ov	VERB
easat-284	207	28	erall	erall	NOUN
easat-284	207	29	mortality	mortality	NOUN
easat-284	207	30	between	between	ADP
easat-284	207	31	patients	patient	NOUN
easat-284	207	32	treated	treat	VERB
easat-284	207	33	with	with	ADP
easat-284	207	34	cp	cp	NUM
easat-284	207	35	and	and	CCONJ
easat-284	207	36	those	those	PRON
easat-284	207	37	who	who	PRON
easat-284	207	38	received	receive	VERB
easat-284	207	39	placebo	placebo	NOUN
easat-284	207	40	and	and	CCONJ
easat-284	207	41	the	the	DET
easat-284	207	42	median	median	ADJ
easat-284	207	43	volume	volume	NOUN
easat-284	207	44	of	of	ADP
easat-284	207	45	infused	infuse	VERB
easat-284	207	46	cp	cp	PROPN
easat-284	207	47	was	be	AUX
easat-284	207	48	500	500	NUM
easat-284	207	49	m.	m.	NOUN
easat-284	207	50	cp	cp	NUM
easat-284	207	51	supply	supply	NOUN
easat-284	207	52	nabs	nab	NOUN
easat-284	207	53	could	could	AUX
easat-284	207	54	be	be	AUX
easat-284	207	55	useful	useful	ADJ
easat-284	207	56	in	in	ADP
easat-284	207	57	the	the	DET
easat-284	207	58	previous	previous	ADJ
easat-284	207	59	phases	phase	NOUN
easat-284	207	60	of	of	ADP
easat-284	207	61	sars	sar	NOUN
easat-284	207	62	-	-	PUNCT
easat-284	207	63	cov-2	cov-2	PART
easat-284	207	64	infection	infection	NOUN
easat-284	207	65	,	,	PUNCT
easat-284	207	66	but	but	CCONJ
easat-284	207	67	clinical	clinical	ADJ
easat-284	207	68	trials	trial	NOUN
easat-284	207	69	with	with	ADP
easat-284	207	70	this	this	DET
easat-284	207	71	target	target	NOUN
easat-284	207	72	are	be	AUX
easat-284	207	73	absent	absent	ADJ
easat-284	207	74	.	.	PUNCT
easat-284	208	1	on	on	ADP
easat-284	208	2	the	the	DET
easat-284	208	3	contrary	contrary	NOUN
easat-284	208	4	,	,	PUNCT
easat-284	208	5	if	if	SCONJ
easat-284	208	6	cp	cp	PROPN
easat-284	208	7	or	or	CCONJ
easat-284	208	8	human	human	ADJ
easat-284	208	9	plasma	plasma	NOUN
easat-284	208	10	and	and	CCONJ
easat-284	208	11	aprotinin	aprotinin	NOUN
easat-284	208	12	are	be	AUX
easat-284	208	13	infused	infuse	VERB
easat-284	208	14	to	to	PART
easat-284	208	15	supply	supply	VERB
easat-284	208	16	serine	serine	ADJ
easat-284	208	17	protease	protease	NOUN
easat-284	208	18	inhibitors	inhibitor	NOUN
easat-284	208	19	as	as	ADP
easat-284	208	20	a	a	DET
easat-284	208	21	“	"	PUNCT
easat-284	208	22	fire	fire	NOUN
easat-284	208	23	extinguisher	extinguisher	NOUN
easat-284	208	24	”	"	PUNCT
easat-284	208	25	for	for	ADP
easat-284	208	26	neutrophils	neutrophil	NOUN
easat-284	208	27	“	"	PUNCT
easat-284	208	28	unfrien	unfrien	ADJ
easat-284	208	29	dly	dly	ADJ
easat-284	208	30	fire	fire	NOUN
easat-284	208	31	”	"	PUNCT
easat-284	208	32	and	and	CCONJ
easat-284	208	33	its	its	PRON
easat-284	208	34	consequences	consequence	NOUN
easat-284	208	35	of	of	ADP
easat-284	208	36	“	"	PUNCT
easat-284	208	37	proteolytic	proteolytic	ADJ
easat-284	208	38	storm	storm	NOUN
easat-284	208	39	”	"	PUNCT
easat-284	208	40	,	,	PUNCT
easat-284	208	41	hypercoagulability	hypercoagulability	NOUN
easat-284	208	42	,	,	PUNCT
easat-284	208	43	thrombosis	thrombosis	NOUN
easat-284	208	44	and	and	CCONJ
easat-284	208	45	sepsis	sepsis	NOUN
easat-284	208	46	with	with	ADP
easat-284	208	47	mof	mof	NOUN
easat-284	208	48	,	,	PUNCT
easat-284	208	49	the	the	DET
easat-284	208	50	infused	infuse	VERB
easat-284	208	51	volume	volume	NOUN
easat-284	208	52	should	should	AUX
easat-284	208	53	be	be	AUX
easat-284	208	54	at	at	ADP
easat-284	208	55	least	least	ADJ
easat-284	208	56	2000	2000	NUM
easat-284	208	57	ml	ml	NOUN
easat-284	208	58	or	or	CCONJ
easat-284	208	59	plasma	plasma	NOUN
easat-284	208	60	-	-	PUNCT
easat-284	208	61	exchange	exchange	NOUN
easat-284	208	62	should	should	AUX
easat-284	208	63	be	be	AUX
easat-284	208	64	performed	perform	VERB
easat-284	208	65	.	.	PUNCT
easat-284	209	1	clinical	clinical	ADJ
easat-284	209	2	trials	trial	NOUN
easat-284	209	3	are	be	AUX
easat-284	209	4	needed	need	VERB
easat-284	209	5	to	to	PART
easat-284	209	6	confirm	confirm	VERB
easat-284	209	7	this	this	DET
easat-284	209	8	hypothesis	hypothesis	NOUN
easat-284	209	9	.	.	PUNCT
easat-284	210	1	references	reference	NOUN
easat-284	210	2	[	[	X
easat-284	210	3	1	1	NUM
easat-284	210	4	]	]	PUNCT
easat-284	210	5	z.	z.	PROPN
easat-284	210	6	wu	wu	PROPN
easat-284	210	7	and	and	CCONJ
easat-284	210	8	j.	j.	PROPN
easat-284	210	9	m.	m.	PROPN
easat-284	210	10	mcgoogan	mcgoogan	PROPN
easat-284	210	11	,	,	PUNCT
easat-284	210	12	"	"	PUNCT
easat-284	210	13	characteristics	characteristic	NOUN
easat-284	210	14	of	of	ADP
easat-284	210	15	and	and	CCONJ
easat-284	210	16	important	important	ADJ
easat-284	210	17	lessons	lesson	NOUN
easat-284	210	18	from	from	ADP
easat-284	210	19	the	the	DET
easat-284	210	20	coronavirus	coronavirus	NOUN
easat-284	210	21	disease	disease	NOUN
easat-284	210	22	2019	2019	NUM
easat-284	210	23	(	(	PUNCT
easat-284	210	24	covid-19	covid-19	PROPN
easat-284	210	25	)	)	PUNCT
easat-284	210	26	outbreak	outbreak	NOUN
easat-284	210	27	in	in	ADP
easat-284	210	28	china	china	PROPN
easat-284	210	29	:	:	PUNCT
easat-284	210	30	summary	summary	NOUN
easat-284	210	31	of	of	ADP
easat-284	210	32	a	a	DET
easat-284	210	33	report	report	NOUN
easat-284	210	34	of	of	ADP
easat-284	210	35	72	72	NUM
easat-284	210	36	314	314	NUM
easat-284	210	37	cases	case	NOUN
easat-284	210	38	from	from	ADP
easat-284	210	39	the	the	DET
easat-284	210	40	chinese	chinese	ADJ
easat-284	210	41	center	center	NOUN
easat-284	210	42	for	for	ADP
easat-284	210	43	disease	disease	NOUN
easat-284	210	44	control	control	NOUN
easat-284	210	45	and	and	CCONJ
easat-284	210	46	prevention	prevention	NOUN
easat-284	210	47	,	,	PUNCT
easat-284	210	48	"	"	PUNCT
easat-284	210	49	jama	jama	NOUN
easat-284	210	50	,	,	PUNCT
easat-284	210	51	vol	vol	NOUN
easat-284	210	52	.	.	PROPN
easat-284	210	53	323	323	NUM
easat-284	210	54	,	,	PUNCT
easat-284	210	55	no	no	INTJ
easat-284	210	56	.	.	NOUN
easat-284	210	57	13	13	NUM
easat-284	210	58	,	,	PUNCT
easat-284	210	59	pp	pp	ADJ
easat-284	210	60	.	.	PUNCT
easat-284	211	1	1239	1239	NUM
easat-284	211	2	-	-	SYM
easat-284	211	3	1242	1242	NUM
easat-284	211	4	,	,	PUNCT
easat-284	211	5	2020	2020	NUM
easat-284	211	6	.	.	PUNCT
easat-284	212	1	[	[	X
easat-284	212	2	2	2	NUM
easat-284	212	3	]	]	PUNCT
easat-284	212	4	c.	c.	PROPN
easat-284	212	5	wu	wu	PROPN
easat-284	212	6	et	et	PROPN
easat-284	212	7	al	al	PROPN
easat-284	212	8	.	.	PROPN
easat-284	212	9	,	,	PUNCT
easat-284	212	10	"	"	PUNCT
easat-284	212	11	risk	risk	NOUN
easat-284	212	12	factors	factor	NOUN
easat-284	212	13	associated	associate	VERB
easat-284	212	14	with	with	ADP
easat-284	212	15	acute	acute	ADJ
easat-284	212	16	respiratory	respiratory	ADJ
easat-284	212	17	distress	distress	NOUN
easat-284	212	18	syndrome	syndrome	NOUN
easat-284	212	19	and	and	CCONJ
easat-284	212	20	death	death	NOUN
easat-284	212	21	in	in	ADP
easat-284	212	22	patients	patient	NOUN
easat-284	212	23	with	with	ADP
easat-284	212	24	coronavirus	coronavirus	NOUN
easat-284	212	25	disease	disease	NOUN
easat-284	212	26	2019	2019	NUM
easat-284	212	27	pneumonia	pneumonia	NOUN
easat-284	212	28	in	in	ADP
easat-284	212	29	wuhan	wuhan	PROPN
easat-284	212	30	,	,	PUNCT
easat-284	212	31	china	china	PROPN
easat-284	212	32	,	,	PUNCT
easat-284	212	33	"	"	PUNCT
easat-284	212	34	jama	jama	PROPN
easat-284	212	35	internal	internal	ADJ
easat-284	212	36	medicine	medicine	NOUN
easat-284	212	37	,	,	PUNCT
easat-284	212	38	vol	vol	NOUN
easat-284	212	39	.	.	PROPN
easat-284	212	40	180	180	NUM
easat-284	212	41	,	,	PUNCT
easat-284	212	42	no	no	INTJ
easat-284	212	43	.	.	NOUN
easat-284	212	44	7	7	NUM
easat-284	212	45	,	,	PUNCT
easat-284	212	46	pp	pp	ADJ
easat-284	212	47	.	.	PUNCT
easat-284	212	48	934	934	NUM
easat-284	212	49	-	-	SYM
easat-284	212	50	943	943	NUM
easat-284	212	51	,	,	PUNCT
easat-284	212	52	2020	2020	NUM
easat-284	212	53	.	.	PUNCT
easat-284	213	1	https://doi.org/10.1111/irv.12804/v1/review1	https://doi.org/10.1111/irv.12804/v1/review1	PROPN
easat-284	214	1	[	[	X
easat-284	214	2	3	3	NUM
easat-284	214	3	]	]	PUNCT
easat-284	214	4	a.	a.	NOUN
easat-284	214	5	c.	c.	PROPN
easat-284	214	6	walls	wall	NOUN
easat-284	214	7	,	,	PUNCT
easat-284	214	8	y.-j	y.-j	PROPN
easat-284	214	9	.	.	PROPN
easat-284	214	10	park	park	PROPN
easat-284	214	11	,	,	PUNCT
easat-284	214	12	m.	m.	NOUN
easat-284	214	13	a.	a.	PROPN
easat-284	214	14	tortorici	tortorici	PROPN
easat-284	214	15	,	,	PUNCT
easat-284	214	16	a.	a.	NOUN
easat-284	214	17	wall	wall	PROPN
easat-284	214	18	,	,	PUNCT
easat-284	214	19	a.	a.	PROPN
easat-284	214	20	t.	t.	PROPN
easat-284	214	21	mcguire	mcguire	PROPN
easat-284	214	22	,	,	PUNCT
easat-284	214	23	and	and	CCONJ
easat-284	214	24	d.	d.	PROPN
easat-284	214	25	veesler	veesler	NOUN
easat-284	214	26	,	,	PUNCT
easat-284	214	27	"	"	PUNCT
easat-284	214	28	structure	structure	NOUN
easat-284	214	29	,	,	PUNCT
easat-284	214	30	function	function	NOUN
easat-284	214	31	,	,	PUNCT
easat-284	214	32	and	and	CCONJ
easat-284	214	33	antigenicity	antigenicity	NOUN
easat-284	214	34	of	of	ADP
easat-284	214	35	the	the	DET
easat-284	214	36	sars	sar	NOUN
easat-284	214	37	-	-	PUNCT
easat-284	214	38	cov-2	cov-2	NOUN
easat-284	214	39	spike	spike	ADJ
easat-284	214	40	glycoprotein	glycoprotein	NOUN
easat-284	214	41	,	,	PUNCT
easat-284	214	42	"	"	PUNCT
easat-284	214	43	cell	cell	NOUN
easat-284	214	44	,	,	PUNCT
easat-284	214	45	vol	vol	NOUN
easat-284	214	46	.	.	PROPN
easat-284	215	1	181	181	NUM
easat-284	215	2	,	,	PUNCT
easat-284	215	3	no	no	INTJ
easat-284	215	4	.	.	NOUN
easat-284	215	5	2	2	NUM
easat-284	215	6	,	,	PUNCT
easat-284	215	7	pp	pp	ADJ
easat-284	215	8	.	.	PUNCT
easat-284	216	1	281	281	NUM
easat-284	216	2	-	-	SYM
easat-284	216	3	292	292	NUM
easat-284	216	4	,	,	PUNCT
easat-284	216	5	2020	2020	NUM
easat-284	216	6	.	.	PUNCT
easat-284	217	1	[	[	X
easat-284	217	2	4	4	NUM
easat-284	217	3	]	]	PUNCT
easat-284	217	4	m.	m.	NOUN
easat-284	217	5	hoffmann	hoffmann	PROPN
easat-284	217	6	et	et	PROPN
easat-284	217	7	al	al	PROPN
easat-284	217	8	.	.	PROPN
easat-284	217	9	,	,	PUNCT
easat-284	217	10	"	"	PUNCT
easat-284	217	11	sars	sar	NOUN
easat-284	217	12	-	-	PUNCT
easat-284	217	13	cov-2	cov-2	NOUN
easat-284	217	14	cell	cell	NOUN
easat-284	217	15	entry	entry	NOUN
easat-284	217	16	depends	depend	VERB
easat-284	217	17	on	on	ADP
easat-284	217	18	ace2	ace2	NOUN
easat-284	217	19	and	and	CCONJ
easat-284	217	20	tmprss2	tmprss2	ADV
easat-284	217	21	and	and	CCONJ
easat-284	217	22	is	be	AUX
easat-284	217	23	blocked	block	VERB
easat-284	217	24	by	by	ADP
easat-284	217	25	a	a	DET
easat-284	217	26	clinically	clinically	ADV
easat-284	217	27	proven	prove	VERB
easat-284	217	28	protease	protease	NOUN
easat-284	217	29	inhibitor	inhibitor	NOUN
easat-284	217	30	,	,	PUNCT
easat-284	217	31	"	"	PUNCT
easat-284	217	32	cell	cell	NOUN
easat-284	217	33	,	,	PUNCT
easat-284	217	34	vol	vol	NOUN
easat-284	217	35	.	.	PROPN
easat-284	218	1	181	181	NUM
easat-284	218	2	,	,	PUNCT
easat-284	218	3	no	no	INTJ
easat-284	218	4	.	.	NOUN
easat-284	218	5	2	2	NUM
easat-284	218	6	,	,	PUNCT
easat-284	218	7	pp	pp	ADJ
easat-284	218	8	.	.	PUNCT
easat-284	219	1	271	271	NUM
easat-284	219	2	-	-	SYM
easat-284	219	3	280	280	NUM
easat-284	219	4	,	,	PUNCT
easat-284	219	5	2020	2020	NUM
easat-284	219	6	.	.	PUNCT
easat-284	220	1	[	[	X
easat-284	220	2	5	5	X
easat-284	220	3	]	]	PUNCT
easat-284	220	4	s.	s.	PROPN
easat-284	220	5	seth	seth	PROPN
easat-284	220	6	,	,	PUNCT
easat-284	220	7	j.	j.	PROPN
easat-284	220	8	batra	batra	PROPN
easat-284	220	9	,	,	PUNCT
easat-284	220	10	and	and	CCONJ
easat-284	220	11	s.	s.	PROPN
easat-284	220	12	srinivasan	srinivasan	PROPN
easat-284	220	13	,	,	PUNCT
easat-284	220	14	"	"	PUNCT
easat-284	220	15	covid-19	covid-19	PROPN
easat-284	220	16	:	:	PUNCT
easat-284	220	17	targeting	target	VERB
easat-284	220	18	proteases	protease	NOUN
easat-284	220	19	in	in	ADP
easat-284	220	20	viral	viral	ADJ
easat-284	220	21	invasion	invasion	NOUN
easat-284	220	22	and	and	CCONJ
easat-284	220	23	host	host	NOUN
easat-284	220	24	immune	immune	ADJ
easat-284	220	25	response	response	NOUN
easat-284	220	26	,	,	PUNCT
easat-284	220	27	"	"	PUNCT
easat-284	220	28	frontiers	frontier	NOUN
easat-284	220	29	in	in	ADP
easat-284	220	30	molecular	molecular	ADJ
easat-284	220	31	biosciences	bioscience	NOUN
easat-284	220	32	,	,	PUNCT
easat-284	220	33	vol	vol	NOUN
easat-284	220	34	.	.	PROPN
easat-284	220	35	7	7	NUM
easat-284	220	36	,	,	PUNCT
easat-284	220	37	p.	p.	NOUN
easat-284	220	38	215	215	NUM
easat-284	220	39	,	,	PUNCT
easat-284	220	40	2020	2020	NUM
easat-284	220	41	.	.	PUNCT
easat-284	221	1	https://doi.org/10.3389/fmolb.2020.00215	https://doi.org/10.3389/fmolb.2020.00215	PROPN
easat-284	222	1	[	[	X
easat-284	222	2	6	6	NUM
easat-284	222	3	]	]	PUNCT
easat-284	222	4	j.	j.	PROPN
easat-284	222	5	shang	shang	PROPN
easat-284	222	6	et	et	PROPN
easat-284	222	7	al	al	PROPN
easat-284	222	8	.	.	PROPN
easat-284	222	9	,	,	PUNCT
easat-284	222	10	"	"	PUNCT
easat-284	222	11	structural	structural	ADJ
easat-284	222	12	basis	basis	NOUN
easat-284	222	13	of	of	ADP
easat-284	222	14	receptor	receptor	NOUN
easat-284	222	15	recognition	recognition	NOUN
easat-284	222	16	by	by	ADP
easat-284	222	17	sars	sar	NOUN
easat-284	222	18	-	-	PUNCT
easat-284	222	19	cov-2	cov-2	NOUN
easat-284	222	20	,	,	PUNCT
easat-284	222	21	"	"	PUNCT
easat-284	222	22	nature	nature	NOUN
easat-284	222	23	,	,	PUNCT
easat-284	222	24	vol	vol	NOUN
easat-284	222	25	.	.	PUNCT
easat-284	223	1	581	581	NUM
easat-284	223	2	,	,	PUNCT
easat-284	223	3	no	no	INTJ
easat-284	223	4	.	.	NOUN
easat-284	223	5	7807	7807	NUM
easat-284	223	6	,	,	PUNCT
easat-284	223	7	pp	pp	ADJ
easat-284	223	8	.	.	PUNCT
easat-284	224	1	221	221	NUM
easat-284	224	2	-	-	SYM
easat-284	224	3	224	224	NUM
easat-284	224	4	,	,	PUNCT
easat-284	224	5	2020	2020	NUM
easat-284	224	6	.	.	PUNCT
easat-284	225	1	[	[	X
easat-284	225	2	7	7	X
easat-284	225	3	]	]	PUNCT
easat-284	225	4	q.	q.	PROPN
easat-284	225	5	wang	wang	PROPN
easat-284	225	6	et	et	PROPN
easat-284	225	7	al	al	PROPN
easat-284	225	8	.	.	PROPN
easat-284	225	9	,	,	PUNCT
easat-284	225	10	"	"	PUNCT
easat-284	225	11	structural	structural	ADJ
easat-284	225	12	and	and	CCONJ
easat-284	225	13	functional	functional	ADJ
easat-284	225	14	basis	basis	NOUN
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easat-284	225	16	sars	sar	NOUN
easat-284	225	17	-	-	PUNCT
easat-284	225	18	cov-2	cov-2	NOUN
easat-284	225	19	entry	entry	NOUN
easat-284	225	20	by	by	ADP
easat-284	225	21	using	use	VERB
easat-284	225	22	human	human	ADJ
easat-284	225	23	ace2	ace2	NOUN
easat-284	225	24	,	,	PUNCT
easat-284	225	25	"	"	PUNCT
easat-284	225	26	cell	cell	NOUN
easat-284	225	27	,	,	PUNCT
easat-284	225	28	vol	vol	NOUN
easat-284	225	29	.	.	PROPN
easat-284	226	1	181	181	NUM
easat-284	226	2	,	,	PUNCT
easat-284	226	3	no	no	INTJ
easat-284	226	4	.	.	NOUN
easat-284	226	5	4	4	NUM
easat-284	226	6	,	,	PUNCT
easat-284	226	7	pp	pp	ADJ
easat-284	226	8	.	.	PUNCT
easat-284	227	1	894904	894904	NUM
easat-284	227	2	,	,	PUNCT
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easat-284	227	4	.	.	PUNCT
easat-284	228	1	https://doi.org/10.3410/f.737704646.793573279	https://doi.org/10.3410/f.737704646.793573279	NOUN
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easat-284	228	11	issn	issn	PROPN
easat-284	228	12	:	:	PUNCT
easat-284	228	13	2576	2576	NUM
easat-284	228	14	-	-	SYM
easat-284	228	15	8484	8484	NUM
easat-284	228	16	vol	vol	NOUN
easat-284	228	17	.	.	PROPN
easat-284	229	1	4	4	NUM
easat-284	229	2	,	,	PUNCT
easat-284	229	3	no	no	INTJ
easat-284	229	4	.	.	NOUN
easat-284	229	5	1	1	NUM
easat-284	229	6	:	:	SYM
easat-284	229	7	67	67	NUM
easat-284	229	8	-	-	SYM
easat-284	229	9	73	73	NUM
easat-284	229	10	,	,	PUNCT
easat-284	229	11	2020	2020	NUM
easat-284	229	12	doi	doi	NOUN
easat-284	229	13	:	:	PUNCT
easat-284	229	14	10.33805/2576	10.33805/2576	NUM
easat-284	229	15	-	-	SYM
easat-284	229	16	8484.184	8484.184	NUM
easat-284	229	17	©	©	PROPN
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easat-284	229	23	8	8	NUM
easat-284	229	24	]	]	X
easat-284	229	25	y.	y.	PROPN
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easat-284	229	27	,	,	PUNCT
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easat-284	229	29	shang	shang	PROPN
easat-284	229	30	,	,	PUNCT
easat-284	229	31	r.	r.	PROPN
easat-284	229	32	graham	graham	PROPN
easat-284	229	33	,	,	PUNCT
easat-284	229	34	r.	r.	PROPN
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easat-284	229	38	and	and	CCONJ
easat-284	229	39	f.	f.	PROPN
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easat-284	229	41	,	,	PUNCT
easat-284	229	42	"	"	PUNCT
easat-284	229	43	receptor	receptor	NOUN
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easat-284	229	71	.	.	PROPN
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easat-284	230	2	,	,	PUNCT
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easat-284	230	4	.	.	NOUN
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easat-284	230	6	,	,	PUNCT
easat-284	230	7	p.	p.	NOUN
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easat-284	230	9	,	,	PUNCT
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easat-284	230	11	.	.	PUNCT
easat-284	231	1	https://doi.org/10.1128/jvi.00127-20	https://doi.org/10.1128/jvi.00127-20	PROPN
easat-284	232	1	[	[	X
easat-284	232	2	9	9	NUM
easat-284	232	3	]	]	PUNCT
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easat-284	232	9	,	,	PUNCT
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easat-284	232	14	waghray	waghray	PROPN
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easat-284	232	16	and	and	CCONJ
easat-284	232	17	g.	g.	PROPN
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easat-284	232	46	-	-	PUNCT
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easat-284	233	8	.	.	PUNCT
easat-284	234	1	[	[	X
easat-284	234	2	10	10	NUM
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easat-284	234	8	.	.	PROPN
easat-284	234	9	,	,	PUNCT
easat-284	234	10	"	"	PUNCT
easat-284	234	11	aprotinin	aprotinin	NOUN
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easat-284	234	14	-	-	PUNCT
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easat-284	234	17	,	,	PUNCT
easat-284	234	18	"	"	PUNCT
easat-284	234	19	cells	cell	NOUN
easat-284	234	20	,	,	PUNCT
easat-284	234	21	vol	vol	NOUN
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easat-284	234	24	,	,	PUNCT
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easat-284	234	28	,	,	PUNCT
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easat-284	234	31	,	,	PUNCT
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easat-284	234	33	.	.	PUNCT
easat-284	235	1	[	[	X
easat-284	235	2	11	11	NUM
easat-284	235	3	]	]	X
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easat-284	235	36	,	,	PUNCT
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easat-284	236	2	-	-	SYM
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easat-284	236	4	,	,	PUNCT
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easat-284	238	2	12	12	NUM
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easat-284	238	32	.	.	PROPN
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easat-284	239	2	,	,	PUNCT
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easat-284	239	9	,	,	PUNCT
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easat-284	239	11	.	.	PUNCT
easat-284	240	1	https://doi.org/10.1101/2020.03.01.20029074	https://doi.org/10.1101/2020.03.01.20029074	PROPN
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easat-284	240	3	13	13	NUM
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easat-284	240	17	,	,	PUNCT
easat-284	240	18	"	"	PUNCT
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easat-284	240	23	,	,	PUNCT
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easat-284	240	25	.	.	PROPN
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easat-284	240	27	,	,	PUNCT
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easat-284	240	31	,	,	PUNCT
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easat-284	240	33	.	.	PUNCT
easat-284	241	1	197	197	NUM
easat-284	241	2	-	-	SYM
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easat-284	241	4	,	,	PUNCT
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easat-284	241	6	.	.	PUNCT
easat-284	242	1	[	[	X
easat-284	242	2	14	14	NUM
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easat-284	242	4	s.	s.	PROPN
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easat-284	242	9	-	-	PUNCT
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easat-284	242	24	,	,	PUNCT
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easat-284	243	2	,	,	PUNCT
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easat-284	244	1	349375	349375	NUM
easat-284	244	2	,	,	PUNCT
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easat-284	244	4	.	.	PUNCT
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easat-284	246	1	united	united	PROPN
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easat-284	247	2	16	16	NUM
easat-284	247	3	]	]	PUNCT
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easat-284	247	19	,	,	PUNCT
easat-284	247	20	virus	virus	NOUN
easat-284	247	21	-	-	PUNCT
easat-284	247	22	host	host	NOUN
easat-284	247	23	interactome	interactome	NOUN
easat-284	247	24	and	and	CCONJ
easat-284	247	25	proteomic	proteomic	ADJ
easat-284	247	26	survey	survey	NOUN
easat-284	247	27	of	of	ADP
easat-284	247	28	pmbcs	pmbc	NOUN
easat-284	247	29	from	from	ADP
easat-284	247	30	covid-19	covid-19	PROPN
easat-284	247	31	patients	patient	NOUN
easat-284	247	32	reveal	reveal	VERB
easat-284	247	33	potential	potential	ADJ
easat-284	247	34	virulence	virulence	NOUN
easat-284	247	35	factors	factor	NOUN
easat-284	247	36	influencing	influence	VERB
easat-284	247	37	sars	sar	NOUN
easat-284	247	38	-	-	PUNCT
easat-284	247	39	cov-2	cov-2	NOUN
easat-284	247	40	pathogenesis	pathogenesis	NOUN
easat-284	247	41	.	.	PUNCT
easat-284	248	1	united	united	PROPN
easat-284	248	2	states	states	PROPN
easat-284	248	3	:	:	PUNCT
easat-284	248	4	csh	csh	PROPN
easat-284	248	5	press	press	PROPN
easat-284	248	6	,	,	PUNCT
easat-284	248	7	2020	2020	NUM
easat-284	248	8	.	.	PUNCT
easat-284	249	1	[	[	X
easat-284	249	2	17	17	NUM
easat-284	249	3	]	]	X
easat-284	249	4	r.	r.	PROPN
easat-284	249	5	karki	karki	PROPN
easat-284	249	6	et	et	PROPN
easat-284	249	7	al	al	PROPN
easat-284	249	8	.	.	PROPN
easat-284	249	9	,	,	PUNCT
easat-284	249	10	"	"	PUNCT
easat-284	249	11	synergism	synergism	NOUN
easat-284	249	12	of	of	ADP
easat-284	249	13	tnf	tnf	PROPN
easat-284	249	14	-	-	PUNCT
easat-284	249	15	α	α	PROPN
easat-284	249	16	and	and	CCONJ
easat-284	249	17	ifn	ifn	PROPN
easat-284	249	18	-	-	PUNCT
easat-284	249	19	γ	γ	NOUN
easat-284	249	20	triggers	trigger	VERB
easat-284	249	21	inflammatory	inflammatory	ADJ
easat-284	249	22	cell	cell	NOUN
easat-284	249	23	death	death	NOUN
easat-284	249	24	,	,	PUNCT
easat-284	249	25	tissue	tissue	NOUN
easat-284	249	26	damage	damage	NOUN
easat-284	249	27	,	,	PUNCT
easat-284	249	28	and	and	CCONJ
easat-284	249	29	mortality	mortality	NOUN
easat-284	249	30	in	in	ADP
easat-284	249	31	sarscov-2	sarscov-2	NUM
easat-284	249	32	infection	infection	NOUN
easat-284	249	33	and	and	CCONJ
easat-284	249	34	cytokine	cytokine	VERB
easat-284	249	35	shock	shock	NOUN
easat-284	249	36	syndromes	syndrome	NOUN
easat-284	249	37	,	,	PUNCT
easat-284	249	38	"	"	PUNCT
easat-284	249	39	cell	cell	NOUN
easat-284	249	40	,	,	PUNCT
easat-284	249	41	vol	vol	NOUN
easat-284	249	42	.	.	PUNCT
easat-284	250	1	184	184	NUM
easat-284	250	2	,	,	PUNCT
easat-284	250	3	no	no	INTJ
easat-284	250	4	.	.	NOUN
easat-284	250	5	1	1	NUM
easat-284	250	6	,	,	PUNCT
easat-284	250	7	pp	pp	ADJ
easat-284	250	8	.	.	PUNCT
easat-284	251	1	149	149	NUM
easat-284	251	2	-	-	SYM
easat-284	251	3	168	168	NUM
easat-284	251	4	,	,	PUNCT
easat-284	251	5	2021	2021	NUM
easat-284	251	6	.	.	PUNCT
easat-284	252	1	https://doi.org/10.1101/2020.10.29.361048	https://doi.org/10.1101/2020.10.29.361048	NOUN
easat-284	252	2	[	[	NOUN
easat-284	252	3	18	18	NUM
easat-284	252	4	]	]	X
easat-284	252	5	d.	d.	PROPN
easat-284	252	6	blanco	blanco	PROPN
easat-284	252	7	-	-	PUNCT
easat-284	252	8	melo	melo	PROPN
easat-284	252	9	et	et	PROPN
easat-284	252	10	al	al	PROPN
easat-284	252	11	.	.	PROPN
easat-284	252	12	,	,	PUNCT
easat-284	252	13	"	"	PUNCT
easat-284	252	14	imbalanced	imbalanced	ADJ
easat-284	252	15	host	host	NOUN
easat-284	252	16	response	response	NOUN
easat-284	252	17	to	to	ADP
easat-284	252	18	sars	sar	NOUN
easat-284	252	19	-	-	PUNCT
easat-284	252	20	cov-2	cov-2	NOUN
easat-284	252	21	drives	drive	VERB
easat-284	252	22	development	development	NOUN
easat-284	252	23	of	of	ADP
easat-284	252	24	covid-19	covid-19	PROPN
easat-284	252	25	,	,	PUNCT
easat-284	252	26	"	"	PUNCT
easat-284	252	27	cell	cell	NOUN
easat-284	252	28	,	,	PUNCT
easat-284	252	29	vol	vol	NOUN
easat-284	252	30	.	.	PROPN
easat-284	253	1	181	181	NUM
easat-284	253	2	,	,	PUNCT
easat-284	253	3	no	no	INTJ
easat-284	253	4	.	.	NOUN
easat-284	253	5	5	5	NUM
easat-284	253	6	,	,	PUNCT
easat-284	253	7	pp	pp	ADJ
easat-284	253	8	.	.	PUNCT
easat-284	254	1	1036	1036	NUM
easat-284	254	2	-	-	SYM
easat-284	254	3	1045	1045	NUM
easat-284	254	4	,	,	PUNCT
easat-284	254	5	2020	2020	NUM
easat-284	254	6	.	.	PUNCT
easat-284	255	1	https://doi.org/10.1016/j.cell.2020.04.026	https://doi.org/10.1016/j.cell.2020.04.026	PROPN
easat-284	255	2	[	[	X
easat-284	255	3	19	19	NUM
easat-284	255	4	]	]	X
easat-284	255	5	c.	c.	PROPN
easat-284	255	6	qin	qin	PROPN
easat-284	255	7	et	et	PROPN
easat-284	255	8	al	al	PROPN
easat-284	255	9	.	.	PROPN
easat-284	255	10	,	,	PUNCT
easat-284	255	11	"	"	PUNCT
easat-284	255	12	dysregulation	dysregulation	NOUN
easat-284	255	13	of	of	ADP
easat-284	255	14	immune	immune	ADJ
easat-284	255	15	response	response	NOUN
easat-284	255	16	in	in	ADP
easat-284	255	17	patients	patient	NOUN
easat-284	255	18	with	with	ADP
easat-284	255	19	coronavirus	coronavirus	NOUN
easat-284	255	20	2019	2019	NUM
easat-284	255	21	(	(	PUNCT
easat-284	255	22	covid-19	covid-19	PROPN
easat-284	255	23	)	)	PUNCT
easat-284	255	24	in	in	ADP
easat-284	255	25	wuhan	wuhan	PROPN
easat-284	255	26	,	,	PUNCT
easat-284	255	27	china	china	PROPN
easat-284	255	28	,	,	PUNCT
easat-284	255	29	"	"	PUNCT
easat-284	255	30	clinical	clinical	ADJ
easat-284	255	31	infectious	infectious	ADJ
easat-284	255	32	diseases	disease	NOUN
easat-284	255	33	,	,	PUNCT
easat-284	255	34	vol	vol	NOUN
easat-284	255	35	.	.	PROPN
easat-284	255	36	71	71	NUM
easat-284	255	37	,	,	PUNCT
easat-284	255	38	no	no	INTJ
easat-284	255	39	.	.	NOUN
easat-284	255	40	15	15	NUM
easat-284	255	41	,	,	PUNCT
easat-284	255	42	pp	pp	ADJ
easat-284	255	43	.	.	PUNCT
easat-284	256	1	762	762	NUM
easat-284	256	2	-	-	SYM
easat-284	256	3	768	768	NUM
easat-284	256	4	,	,	PUNCT
easat-284	256	5	2020	2020	NUM
easat-284	256	6	.	.	PUNCT
easat-284	257	1	https://doi.org/10.1093/cid/ciaa248	https://doi.org/10.1093/cid/ciaa248	PROPN
easat-284	258	1	[	[	X
easat-284	258	2	20	20	NUM
easat-284	258	3	]	]	PUNCT
easat-284	258	4	h.	h.	PROPN
easat-284	258	5	wang	wang	PROPN
easat-284	258	6	,	,	PUNCT
easat-284	258	7	t.	t.	PROPN
easat-284	258	8	yi	yi	PROPN
easat-284	258	9	,	,	PUNCT
easat-284	258	10	y.	y.	PROPN
easat-284	258	11	zheng	zheng	PROPN
easat-284	258	12	,	,	PUNCT
easat-284	258	13	and	and	CCONJ
easat-284	258	14	s.	s.	PROPN
easat-284	258	15	he	he	PRON
easat-284	258	16	,	,	PUNCT
easat-284	258	17	"	"	PUNCT
easat-284	258	18	induction	induction	NOUN
easat-284	258	19	of	of	ADP
easat-284	258	20	monocyte	monocyte	NOUN
easat-284	258	21	chemoattractant	chemoattractant	NOUN
easat-284	258	22	protein-1	protein-1	PROPN
easat-284	258	23	release	release	NOUN
easat-284	258	24	from	from	ADP
easat-284	258	25	a549	a549	PROPN
easat-284	258	26	cells	cell	NOUN
easat-284	258	27	by	by	ADP
easat-284	258	28	agonists	agonist	NOUN
easat-284	258	29	of	of	ADP
easat-284	258	30	protease	protease	NOUN
easat-284	258	31	-	-	PUNCT
easat-284	258	32	activated	activate	VERB
easat-284	258	33	receptor-1	receptor-1	NUM
easat-284	258	34	and-2	and-2	NOUN
easat-284	258	35	,	,	PUNCT
easat-284	258	36	"	"	PUNCT
easat-284	258	37	european	european	ADJ
easat-284	258	38	journal	journal	PROPN
easat-284	258	39	of	of	ADP
easat-284	258	40	cell	cell	NOUN
easat-284	258	41	biology	biology	NOUN
easat-284	258	42	,	,	PUNCT
easat-284	258	43	vol	vol	NOUN
easat-284	258	44	.	.	PROPN
easat-284	258	45	86	86	NUM
easat-284	258	46	,	,	PUNCT
easat-284	258	47	no	no	INTJ
easat-284	258	48	.	.	NOUN
easat-284	258	49	4	4	NUM
easat-284	258	50	,	,	PUNCT
easat-284	258	51	pp	pp	ADJ
easat-284	258	52	.	.	PUNCT
easat-284	259	1	233	233	NUM
easat-284	259	2	-	-	SYM
easat-284	259	3	242	242	NUM
easat-284	259	4	,	,	PUNCT
easat-284	259	5	2007	2007	NUM
easat-284	259	6	.	.	PUNCT
easat-284	260	1	https://doi.org/10.1016/j.ejcb.2006.12.003	https://doi.org/10.1016/j.ejcb.2006.12.003	NOUN
easat-284	261	1	[	[	X
easat-284	261	2	21	21	NUM
easat-284	261	3	]	]	X
easat-284	261	4	n.	n.	NOUN
easat-284	261	5	méthot	méthot	PROPN
easat-284	261	6	et	et	PROPN
easat-284	261	7	al	al	PROPN
easat-284	261	8	.	.	PROPN
easat-284	261	9	,	,	PUNCT
easat-284	261	10	"	"	PUNCT
easat-284	261	11	inhibition	inhibition	NOUN
easat-284	261	12	of	of	ADP
easat-284	261	13	the	the	DET
easat-284	261	14	activation	activation	NOUN
easat-284	261	15	of	of	ADP
easat-284	261	16	multiple	multiple	ADJ
easat-284	261	17	serine	serine	NOUN
easat-284	261	18	proteases	protease	NOUN
easat-284	261	19	with	with	ADP
easat-284	261	20	a	a	DET
easat-284	261	21	cathepsin	cathepsin	NOUN
easat-284	261	22	c	c	NOUN
easat-284	261	23	inhibitor	inhibitor	NOUN
easat-284	261	24	requires	require	VERB
easat-284	261	25	sustained	sustain	VERB
easat-284	261	26	exposure	exposure	NOUN
easat-284	261	27	to	to	PART
easat-284	261	28	prevent	prevent	VERB
easat-284	261	29	pro	pro	ADJ
easat-284	261	30	-	-	ADJ
easat-284	261	31	enzyme	enzyme	ADJ
easat-284	261	32	processing	processing	NOUN
easat-284	261	33	,	,	PUNCT
easat-284	261	34	"	"	PUNCT
easat-284	261	35	journal	journal	NOUN
easat-284	261	36	of	of	ADP
easat-284	261	37	biological	biological	ADJ
easat-284	261	38	chemistry	chemistry	NOUN
easat-284	261	39	,	,	PUNCT
easat-284	261	40	vol	vol	NOUN
easat-284	261	41	.	.	PROPN
easat-284	262	1	282	282	NUM
easat-284	262	2	,	,	PUNCT
easat-284	262	3	no	no	INTJ
easat-284	262	4	.	.	NOUN
easat-284	262	5	29	29	NUM
easat-284	262	6	,	,	PUNCT
easat-284	262	7	pp	pp	ADJ
easat-284	262	8	.	.	PUNCT
easat-284	263	1	20836	20836	NUM
easat-284	263	2	-	-	SYM
easat-284	263	3	20846	20846	NUM
easat-284	263	4	,	,	PUNCT
easat-284	263	5	2007	2007	NUM
easat-284	263	6	.	.	PUNCT
easat-284	264	1	https://doi.org/10.1074/jbc.m702615200	https://doi.org/10.1074/jbc.m702615200	PRON
easat-284	265	1	[	[	X
easat-284	265	2	22	22	NUM
easat-284	265	3	]	]	PUNCT
easat-284	265	4	k.	k.	PROPN
easat-284	265	5	m.	m.	PROPN
easat-284	265	6	heutinck	heutinck	PROPN
easat-284	265	7	,	,	PUNCT
easat-284	265	8	i.	i.	PROPN
easat-284	265	9	j.	j.	PROPN
easat-284	265	10	ten	ten	NUM
easat-284	265	11	berge	berge	PROPN
easat-284	265	12	,	,	PUNCT
easat-284	265	13	c.	c.	PROPN
easat-284	265	14	e.	e.	PROPN
easat-284	265	15	hack	hack	PROPN
easat-284	265	16	,	,	PUNCT
easat-284	265	17	j.	j.	PROPN
easat-284	265	18	hamann	hamann	PROPN
easat-284	265	19	,	,	PUNCT
easat-284	265	20	and	and	CCONJ
easat-284	265	21	a.	a.	NOUN
easat-284	265	22	t.	t.	PROPN
easat-284	265	23	rowshani	rowshani	PROPN
easat-284	265	24	,	,	PUNCT
easat-284	265	25	"	"	PUNCT
easat-284	265	26	serine	serine	NOUN
easat-284	265	27	proteases	protease	NOUN
easat-284	265	28	of	of	ADP
easat-284	265	29	the	the	DET
easat-284	265	30	human	human	ADJ
easat-284	265	31	immune	immune	ADJ
easat-284	265	32	system	system	NOUN
easat-284	265	33	in	in	ADP
easat-284	265	34	health	health	NOUN
easat-284	265	35	and	and	CCONJ
easat-284	265	36	disease	disease	NOUN
easat-284	265	37	,	,	PUNCT
easat-284	265	38	"	"	PUNCT
easat-284	265	39	molecular	molecular	ADJ
easat-284	265	40	immunology	immunology	NOUN
easat-284	265	41	,	,	PUNCT
easat-284	265	42	vol	vol	NOUN
easat-284	265	43	.	.	PROPN
easat-284	266	1	47	47	NUM
easat-284	266	2	,	,	PUNCT
easat-284	266	3	no	no	INTJ
easat-284	266	4	.	.	NOUN
easat-284	266	5	11	11	NUM
easat-284	266	6	-	-	SYM
easat-284	266	7	12	12	NUM
easat-284	266	8	,	,	PUNCT
easat-284	266	9	pp	pp	ADJ
easat-284	266	10	.	.	PUNCT
easat-284	266	11	1943	1943	NUM
easat-284	266	12	-	-	SYM
easat-284	266	13	1955	1955	NUM
easat-284	266	14	,	,	PUNCT
easat-284	266	15	2010	2010	NUM
easat-284	266	16	.	.	PUNCT
easat-284	267	1	[	[	X
easat-284	267	2	23	23	NUM
easat-284	267	3	]	]	X
easat-284	267	4	l.	l.	PROPN
easat-284	267	5	antonioli	antonioli	PROPN
easat-284	267	6	,	,	PUNCT
easat-284	267	7	m.	m.	NOUN
easat-284	267	8	fornai	fornai	PROPN
easat-284	267	9	,	,	PUNCT
easat-284	267	10	c.	c.	PROPN
easat-284	267	11	pellegrini	pellegrini	PROPN
easat-284	267	12	,	,	PUNCT
easat-284	267	13	and	and	CCONJ
easat-284	267	14	c.	c.	PROPN
easat-284	267	15	blandizzi	blandizzi	PROPN
easat-284	267	16	,	,	PUNCT
easat-284	267	17	"	"	PUNCT
easat-284	267	18	nkg2a	nkg2a	PROPN
easat-284	267	19	and	and	CCONJ
easat-284	267	20	covid-19	covid-19	PROPN
easat-284	267	21	:	:	PUNCT
easat-284	267	22	another	another	DET
easat-284	267	23	brick	brick	NOUN
easat-284	267	24	in	in	ADP
easat-284	267	25	the	the	DET
easat-284	267	26	wall	wall	NOUN
easat-284	267	27	,	,	PUNCT
easat-284	267	28	"	"	PUNCT
easat-284	267	29	cellular	cellular	ADJ
easat-284	267	30	&	&	CCONJ
easat-284	267	31	molecular	molecular	ADJ
easat-284	267	32	immunology	immunology	NOUN
easat-284	267	33	,	,	PUNCT
easat-284	267	34	vol	vol	NOUN
easat-284	267	35	.	.	PROPN
easat-284	267	36	17	17	NUM
easat-284	267	37	,	,	PUNCT
easat-284	267	38	no	no	INTJ
easat-284	267	39	.	.	NOUN
easat-284	267	40	6	6	NUM
easat-284	267	41	,	,	PUNCT
easat-284	267	42	pp	pp	ADJ
easat-284	267	43	.	.	PUNCT
easat-284	268	1	672	672	NUM
easat-284	268	2	-	-	SYM
easat-284	268	3	674	674	NUM
easat-284	268	4	,	,	PUNCT
easat-284	268	5	2020	2020	NUM
easat-284	268	6	.	.	PUNCT
easat-284	269	1	https://doi.org/10.1038/s41423-020-0450-7	https://doi.org/10.1038/s41423-020-0450-7	NUM
easat-284	269	2	[	[	X
easat-284	269	3	24	24	NUM
easat-284	269	4	]	]	PUNCT
easat-284	269	5	m.	m.	NOUN
easat-284	269	6	hashizume	hashizume	NOUN
easat-284	269	7	,	,	PUNCT
easat-284	269	8	y.	y.	PROPN
easat-284	269	9	higuchi	higuchi	PROPN
easat-284	269	10	,	,	PUNCT
easat-284	269	11	y.	y.	PROPN
easat-284	269	12	uchiyama	uchiyama	NOUN
easat-284	269	13	,	,	PUNCT
easat-284	269	14	and	and	CCONJ
easat-284	269	15	m.	m.	NOUN
easat-284	269	16	mihara	mihara	PROPN
easat-284	269	17	,	,	PUNCT
easat-284	269	18	"	"	PUNCT
easat-284	269	19	il-6	il-6	PRON
easat-284	269	20	plays	play	VERB
easat-284	269	21	an	an	DET
easat-284	269	22	essential	essential	ADJ
easat-284	269	23	role	role	NOUN
easat-284	269	24	in	in	ADP
easat-284	269	25	neutrophilia	neutrophilia	PROPN
easat-284	269	26	under	under	ADP
easat-284	269	27	inflammation	inflammation	NOUN
easat-284	269	28	,	,	PUNCT
easat-284	269	29	"	"	PUNCT
easat-284	269	30	cytokine	cytokine	NOUN
easat-284	269	31	,	,	PUNCT
easat-284	269	32	vol	vol	NOUN
easat-284	269	33	.	.	PROPN
easat-284	270	1	54	54	NUM
easat-284	270	2	,	,	PUNCT
easat-284	270	3	no	no	INTJ
easat-284	270	4	.	.	NOUN
easat-284	270	5	1	1	NUM
easat-284	270	6	,	,	PUNCT
easat-284	270	7	pp	pp	ADJ
easat-284	270	8	.	.	PUNCT
easat-284	271	1	92	92	NUM
easat-284	271	2	-	-	SYM
easat-284	271	3	99	99	NUM
easat-284	271	4	,	,	PUNCT
easat-284	271	5	2011	2011	NUM
easat-284	271	6	.	.	PUNCT
easat-284	272	1	https://doi.org/10.1016/j.cyto.2011.01.007	https://doi.org/10.1016/j.cyto.2011.01.007	PROPN
easat-284	272	2	[	[	X
easat-284	272	3	25	25	NUM
easat-284	272	4	]	]	PUNCT
easat-284	272	5	a.	a.	PROPN
easat-284	272	6	wozniak	wozniak	PROPN
easat-284	272	7	,	,	PUNCT
easat-284	272	8	w.	w.	PROPN
easat-284	272	9	betts	betts	PROPN
easat-284	272	10	,	,	PUNCT
easat-284	272	11	g.	g.	PROPN
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easat-284	272	13	,	,	PUNCT
easat-284	272	14	and	and	CCONJ
easat-284	272	15	m.	m.	PROPN
easat-284	272	16	rokicinski	rokicinski	PROPN
easat-284	272	17	,	,	PUNCT
easat-284	272	18	"	"	PUNCT
easat-284	272	19	interleukin-8	interleukin-8	PRON
easat-284	272	20	primes	prime	VERB
easat-284	272	21	human	human	ADJ
easat-284	272	22	neutrophils	neutrophil	NOUN
easat-284	272	23	for	for	ADP
easat-284	272	24	enhanced	enhanced	ADJ
easat-284	272	25	superoxide	superoxide	NOUN
easat-284	272	26	anion	anion	NOUN
easat-284	272	27	production	production	NOUN
easat-284	272	28	,	,	PUNCT
easat-284	272	29	"	"	PUNCT
easat-284	272	30	immunology	immunology	NOUN
easat-284	272	31	,	,	PUNCT
easat-284	272	32	vol	vol	NOUN
easat-284	272	33	.	.	PROPN
easat-284	273	1	79	79	NUM
easat-284	273	2	,	,	PUNCT
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easat-284	273	4	.	.	NOUN
easat-284	273	5	4	4	NUM
easat-284	273	6	,	,	PUNCT
easat-284	273	7	p.	p.	NOUN
easat-284	273	8	608	608	NUM
easat-284	273	9	,	,	PUNCT
easat-284	273	10	1993	1993	NUM
easat-284	273	11	.	.	PUNCT
easat-284	274	1	https://doi.org/10.3109/08923979709038538	https://doi.org/10.3109/08923979709038538	X
easat-284	275	1	[	[	X
easat-284	275	2	26	26	NUM
easat-284	275	3	]	]	PUNCT
easat-284	276	1	b.	b.	PROPN
easat-284	276	2	nandi	nandi	PROPN
easat-284	276	3	and	and	CCONJ
easat-284	276	4	s.	s.	PROPN
easat-284	276	5	m.	m.	PROPN
easat-284	276	6	behar	behar	PROPN
easat-284	276	7	,	,	PUNCT
easat-284	276	8	"	"	PUNCT
easat-284	276	9	regulation	regulation	NOUN
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easat-284	276	11	neutrophils	neutrophil	NOUN
easat-284	276	12	by	by	ADP
easat-284	276	13	interferon	interferon	ADJ
easat-284	276	14	-	-	PUNCT
easat-284	276	15	γ	γ	NOUN
easat-284	276	16	limits	limit	NOUN
easat-284	276	17	lung	lung	NOUN
easat-284	276	18	inflammation	inflammation	NOUN
easat-284	276	19	during	during	ADP
easat-284	276	20	tuberculosis	tuberculosis	NOUN
easat-284	276	21	infection	infection	NOUN
easat-284	276	22	,	,	PUNCT
easat-284	276	23	"	"	PUNCT
easat-284	276	24	journal	journal	NOUN
easat-284	276	25	of	of	ADP
easat-284	276	26	experimental	experimental	ADJ
easat-284	276	27	medicine	medicine	NOUN
easat-284	276	28	,	,	PUNCT
easat-284	276	29	vol	vol	NOUN
easat-284	276	30	.	.	PROPN
easat-284	276	31	208	208	NUM
easat-284	276	32	,	,	PUNCT
easat-284	276	33	no	no	INTJ
easat-284	276	34	.	.	NOUN
easat-284	276	35	11	11	NUM
easat-284	276	36	,	,	PUNCT
easat-284	276	37	pp	pp	ADJ
easat-284	276	38	.	.	PUNCT
easat-284	276	39	2251	2251	NUM
easat-284	276	40	-	-	SYM
easat-284	276	41	2262	2262	NUM
easat-284	276	42	,	,	PUNCT
easat-284	276	43	2011	2011	NUM
easat-284	276	44	.	.	PUNCT
easat-284	277	1	https://doi.org/10.1084/jem.20110919	https://doi.org/10.1084/jem.20110919	PROPN
easat-284	278	1	[	[	X
easat-284	278	2	27	27	NUM
easat-284	278	3	]	]	PUNCT
easat-284	278	4	z.	z.	PROPN
easat-284	278	5	xu	xu	PROPN
easat-284	278	6	et	et	PROPN
easat-284	278	7	al	al	PROPN
easat-284	278	8	.	.	PROPN
easat-284	278	9	,	,	PUNCT
easat-284	278	10	"	"	PUNCT
easat-284	278	11	pathological	pathological	ADJ
easat-284	278	12	findings	finding	NOUN
easat-284	278	13	of	of	ADP
easat-284	278	14	covid-19	covid-19	PROPN
easat-284	278	15	associated	associate	VERB
easat-284	278	16	with	with	ADP
easat-284	278	17	acute	acute	ADJ
easat-284	278	18	respiratory	respiratory	ADJ
easat-284	278	19	distress	distress	NOUN
easat-284	278	20	syndrome	syndrome	NOUN
easat-284	278	21	,	,	PUNCT
easat-284	278	22	"	"	PUNCT
easat-284	278	23	the	the	DET
easat-284	278	24	lancet	lancet	ADJ
easat-284	278	25	respiratory	respiratory	ADJ
easat-284	278	26	medicine	medicine	NOUN
easat-284	278	27	,	,	PUNCT
easat-284	278	28	vol	vol	NOUN
easat-284	278	29	.	.	PROPN
easat-284	278	30	8	8	NUM
easat-284	278	31	,	,	PUNCT
easat-284	278	32	no	no	INTJ
easat-284	278	33	.	.	NOUN
easat-284	278	34	4	4	NUM
easat-284	278	35	,	,	PUNCT
easat-284	278	36	pp	pp	ADJ
easat-284	278	37	.	.	PUNCT
easat-284	278	38	420	420	NUM
easat-284	278	39	-	-	SYM
easat-284	278	40	422	422	NUM
easat-284	278	41	,	,	PUNCT
easat-284	278	42	2020	2020	NUM
easat-284	278	43	.	.	PUNCT
easat-284	279	1	[	[	X
easat-284	279	2	28	28	NUM
easat-284	279	3	]	]	X
easat-284	279	4	r.	r.	PROPN
easat-284	279	5	j.	j.	PROPN
easat-284	279	6	mason	mason	PROPN
easat-284	279	7	,	,	PUNCT
easat-284	279	8	"	"	PUNCT
easat-284	279	9	pathogenesis	pathogenesis	NOUN
easat-284	279	10	of	of	ADP
easat-284	279	11	covid-19	covid-19	PROPN
easat-284	279	12	from	from	ADP
easat-284	279	13	a	a	DET
easat-284	279	14	cell	cell	NOUN
easat-284	279	15	biology	biology	NOUN
easat-284	279	16	perspective	perspective	NOUN
easat-284	279	17	,	,	PUNCT
easat-284	279	18	"	"	PUNCT
easat-284	279	19	eur	eur	ADJ
easat-284	279	20	respiratory	respiratory	ADJ
easat-284	279	21	soc	soc	NOUN
easat-284	279	22	,	,	PUNCT
easat-284	279	23	vol	vol	NOUN
easat-284	279	24	.	.	PROPN
easat-284	279	25	55	55	NUM
easat-284	279	26	,	,	PUNCT
easat-284	279	27	no	no	INTJ
easat-284	279	28	.	.	NOUN
easat-284	279	29	4	4	NUM
easat-284	279	30	,	,	PUNCT
easat-284	279	31	2020	2020	NUM
easat-284	279	32	.	.	PUNCT
easat-284	279	33	https://doi.org/10.1183/13993003.00607-2020	https://doi.org/10.1183/13993003.00607-2020	X
easat-284	280	1	[	[	X
easat-284	280	2	29	29	NUM
easat-284	280	3	]	]	X
easat-284	280	4	c.	c.	PROPN
easat-284	280	5	magro	magro	PROPN
easat-284	280	6	et	et	PROPN
easat-284	280	7	al	al	PROPN
easat-284	280	8	.	.	PROPN
easat-284	280	9	,	,	PUNCT
easat-284	280	10	"	"	PUNCT
easat-284	280	11	complement	complement	VERB
easat-284	280	12	associated	associate	VERB
easat-284	280	13	microvascular	microvascular	NOUN
easat-284	280	14	injury	injury	NOUN
easat-284	280	15	and	and	CCONJ
easat-284	280	16	thrombosis	thrombosis	NOUN
easat-284	280	17	in	in	ADP
easat-284	280	18	the	the	DET
easat-284	280	19	pathogenesis	pathogenesis	NOUN
easat-284	280	20	of	of	ADP
easat-284	280	21	severe	severe	ADJ
easat-284	280	22	covid-19	covid-19	PROPN
easat-284	280	23	infection	infection	NOUN
easat-284	280	24	:	:	PUNCT
easat-284	280	25	a	a	DET
easat-284	280	26	report	report	NOUN
easat-284	280	27	of	of	ADP
easat-284	280	28	five	five	NUM
easat-284	280	29	cases	case	NOUN
easat-284	280	30	,	,	PUNCT
easat-284	280	31	"	"	PUNCT
easat-284	280	32	translational	translational	ADJ
easat-284	280	33	research	research	NOUN
easat-284	280	34	,	,	PUNCT
easat-284	280	35	vol	vol	NOUN
easat-284	280	36	.	.	NOUN
easat-284	280	37	220	220	NUM
easat-284	280	38	,	,	PUNCT
easat-284	280	39	pp	pp	ADJ
easat-284	280	40	.	.	PUNCT
easat-284	281	1	1	1	NUM
easat-284	281	2	-	-	SYM
easat-284	281	3	13	13	NUM
easat-284	281	4	,	,	PUNCT
easat-284	281	5	2020	2020	NUM
easat-284	281	6	.	.	PUNCT
easat-284	282	1	https://doi.org/10.1016/j.trsl.2020.04.007	https://doi.org/10.1016/j.trsl.2020.04.007	PROPN
easat-284	283	1	[	[	X
easat-284	283	2	30	30	NUM
easat-284	283	3	]	]	PUNCT
easat-284	283	4	h.	h.	PROPN
easat-284	283	5	zhou	zhou	PROPN
easat-284	283	6	et	et	PROPN
easat-284	283	7	al	al	PROPN
easat-284	283	8	.	.	PROPN
easat-284	283	9	,	,	PUNCT
easat-284	283	10	"	"	PUNCT
easat-284	283	11	platelet	platelet	NOUN
easat-284	283	12	hmgb1	hmgb1	PROPN
easat-284	283	13	is	be	AUX
easat-284	283	14	required	require	VERB
easat-284	283	15	for	for	ADP
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easat-284	283	17	bacterial	bacterial	ADJ
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easat-284	283	19	in	in	ADP
easat-284	283	20	intra	intra	ADJ
easat-284	283	21	-	-	ADJ
easat-284	283	22	abdominal	abdominal	ADJ
easat-284	283	23	bacterial	bacterial	ADJ
easat-284	283	24	sepsis	sepsis	NOUN
easat-284	283	25	in	in	ADP
easat-284	283	26	mice	mouse	NOUN
easat-284	283	27	,	,	PUNCT
easat-284	283	28	"	"	PUNCT
easat-284	283	29	blood	blood	NOUN
easat-284	283	30	advances	advance	NOUN
easat-284	283	31	,	,	PUNCT
easat-284	283	32	vol	vol	NOUN
easat-284	283	33	.	.	PROPN
easat-284	283	34	2	2	NUM
easat-284	283	35	,	,	PUNCT
easat-284	283	36	no	no	INTJ
easat-284	283	37	.	.	NOUN
easat-284	283	38	6	6	NUM
easat-284	283	39	,	,	PUNCT
easat-284	283	40	pp	pp	ADJ
easat-284	283	41	.	.	PUNCT
easat-284	284	1	638	638	NUM
easat-284	284	2	-	-	SYM
easat-284	284	3	648	648	NUM
easat-284	284	4	,	,	PUNCT
easat-284	284	5	2018	2018	NUM
easat-284	284	6	.	.	PUNCT
easat-284	285	1	https://doi.org/10.1182/bloodadvances.2017011817	https://doi.org/10.1182/bloodadvances.2017011817	NOUN
easat-284	286	1	[	[	X
easat-284	286	2	31	31	NUM
easat-284	286	3	]	]	PUNCT
easat-284	286	4	p.	p.	PROPN
easat-284	286	5	conti	conti	PROPN
easat-284	286	6	et	et	PROPN
easat-284	286	7	al	al	PROPN
easat-284	286	8	.	.	PROPN
easat-284	286	9	,	,	PUNCT
easat-284	286	10	"	"	PUNCT
easat-284	286	11	induction	induction	NOUN
easat-284	286	12	of	of	ADP
easat-284	286	13	pro	pro	ADJ
easat-284	286	14	-	-	ADJ
easat-284	286	15	inflammatory	inflammatory	ADJ
easat-284	286	16	cytokines	cytokine	NOUN
easat-284	286	17	(	(	PUNCT
easat-284	286	18	il-1	il-1	X
easat-284	286	19	and	and	CCONJ
easat-284	286	20	il-6	il-6	NUM
easat-284	286	21	)	)	PUNCT
easat-284	286	22	and	and	CCONJ
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easat-284	286	24	inflammation	inflammation	NOUN
easat-284	286	25	by	by	ADP
easat-284	286	26	coronavirus-19	coronavirus-19	PROPN
easat-284	286	27	(	(	PUNCT
easat-284	286	28	covi19	covi19	NOUN
easat-284	286	29	or	or	CCONJ
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easat-284	286	31	-	-	PUNCT
easat-284	286	32	cov-2	cov-2	NOUN
easat-284	286	33	):	):	PUNCT
easat-284	286	34	anti	anti	ADJ
easat-284	286	35	-	-	ADJ
easat-284	286	36	inflammatory	inflammatory	ADJ
easat-284	286	37	strategies	strategy	NOUN
easat-284	286	38	,	,	PUNCT
easat-284	286	39	"	"	PUNCT
easat-284	286	40	j	j	PROPN
easat-284	286	41	biol	biol	PROPN
easat-284	286	42	regul	regul	PROPN
easat-284	286	43	homeost	homeost	ADJ
easat-284	286	44	agents	agent	NOUN
easat-284	286	45	,	,	PUNCT
easat-284	286	46	vol	vol	NOUN
easat-284	286	47	.	.	PROPN
easat-284	286	48	34	34	NUM
easat-284	286	49	,	,	PUNCT
easat-284	286	50	no	no	INTJ
easat-284	286	51	.	.	NOUN
easat-284	286	52	2	2	NUM
easat-284	286	53	,	,	PUNCT
easat-284	286	54	pp	pp	ADJ
easat-284	286	55	.	.	PUNCT
easat-284	287	1	327	327	NUM
easat-284	287	2	-	-	SYM
easat-284	287	3	331	331	NUM
easat-284	287	4	,	,	PUNCT
easat-284	287	5	2020	2020	NUM
easat-284	287	6	.	.	PUNCT
easat-284	288	1	[	[	X
easat-284	288	2	32	32	NUM
easat-284	288	3	]	]	PUNCT
easat-284	288	4	c.	c.	PROPN
easat-284	288	5	zhang	zhang	PROPN
easat-284	288	6	,	,	PUNCT
easat-284	288	7	z.	z.	PROPN
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easat-284	288	9	,	,	PUNCT
easat-284	288	10	j.-w	j.-w	PROPN
easat-284	288	11	.	.	PUNCT
easat-284	289	1	li	li	PROPN
easat-284	289	2	,	,	PUNCT
easat-284	289	3	h.	h.	PROPN
easat-284	289	4	zhao	zhao	PROPN
easat-284	289	5	,	,	PUNCT
easat-284	289	6	and	and	CCONJ
easat-284	289	7	g.-q	g.-q	PROPN
easat-284	289	8	.	.	PUNCT
easat-284	290	1	wang	wang	PROPN
easat-284	290	2	,	,	PUNCT
easat-284	290	3	"	"	PUNCT
easat-284	290	4	cytokine	cytokine	VERB
easat-284	290	5	release	release	NOUN
easat-284	290	6	syndrome	syndrome	NOUN
easat-284	290	7	in	in	ADP
easat-284	290	8	severe	severe	ADJ
easat-284	290	9	covid-19	covid-19	PROPN
easat-284	290	10	:	:	PUNCT
easat-284	290	11	interleukin-6	interleukin-6	NUM
easat-284	290	12	receptor	receptor	NOUN
easat-284	290	13	antagonist	antagonist	NOUN
easat-284	290	14	tocilizumab	tocilizumab	NOUN
easat-284	290	15	may	may	AUX
easat-284	290	16	be	be	AUX
easat-284	290	17	the	the	DET
easat-284	290	18	key	key	NOUN
easat-284	290	19	to	to	PART
easat-284	290	20	reduce	reduce	VERB
easat-284	290	21	mortality	mortality	NOUN
easat-284	290	22	,	,	PUNCT
easat-284	290	23	"	"	PUNCT
easat-284	290	24	international	international	ADJ
easat-284	290	25	journal	journal	NOUN
easat-284	290	26	of	of	ADP
easat-284	290	27	antimicrobial	antimicrobial	ADJ
easat-284	290	28	agents	agent	NOUN
easat-284	290	29	,	,	PUNCT
easat-284	290	30	vol	vol	NOUN
easat-284	290	31	.	.	PROPN
easat-284	291	1	55	55	NUM
easat-284	291	2	,	,	PUNCT
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easat-284	291	4	.	.	NOUN
easat-284	291	5	5	5	NUM
easat-284	291	6	,	,	PUNCT
easat-284	291	7	p.	p.	NOUN
easat-284	291	8	105954	105954	NUM
easat-284	291	9	,	,	PUNCT
easat-284	291	10	2020	2020	NUM
easat-284	291	11	.	.	PUNCT
easat-284	292	1	https://doi.org/10.1016/j.ijantimicag.2020.105954	https://doi.org/10.1016/j.ijantimicag.2020.105954	VERB
easat-284	292	2	[	[	X
easat-284	292	3	33	33	NUM
easat-284	292	4	]	]	X
easat-284	292	5	v.	v.	ADP
easat-284	292	6	rizo	rizo	PROPN
easat-284	292	7	-	-	PUNCT
easat-284	292	8	delgado	delgado	PROPN
easat-284	292	9	,	,	PUNCT
easat-284	292	10	m.	m.	NOUN
easat-284	292	11	a.	a.	PROPN
easat-284	292	12	martínez	martínez	PROPN
easat-284	292	13	-	-	PUNCT
easat-284	292	14	guzmán	guzmán	PROPN
easat-284	292	15	,	,	PUNCT
easat-284	292	16	l.	l.	PROPN
easat-284	292	17	iñiguez	iñiguez	PROPN
easat-284	292	18	-	-	PUNCT
easat-284	292	19	gutierrez	gutierrez	PROPN
easat-284	292	20	,	,	PUNCT
easat-284	292	21	a.	a.	NOUN
easat-284	292	22	garcía	garcía	NOUN
easat-284	292	23	-	-	PUNCT
easat-284	292	24	orozco	orozco	PROPN
easat-284	292	25	,	,	PUNCT
easat-284	292	26	a.	a.	PROPN
easat-284	292	27	alvarado	alvarado	PROPN
easat-284	292	28	-	-	PUNCT
easat-284	292	29	navarro	navarro	PROPN
easat-284	292	30	,	,	PUNCT
easat-284	292	31	and	and	CCONJ
easat-284	292	32	m.	m.	PROPN
easat-284	292	33	fafutismorris	fafutismorris	PROPN
easat-284	292	34	,	,	PUNCT
easat-284	292	35	"	"	PUNCT
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easat-284	292	37	extracellular	extracellular	ADJ
easat-284	292	38	traps	trap	NOUN
easat-284	292	39	and	and	CCONJ
easat-284	292	40	its	its	PRON
easat-284	292	41	implications	implication	NOUN
easat-284	292	42	in	in	ADP
easat-284	292	43	inflammation	inflammation	NOUN
easat-284	292	44	:	:	PUNCT
easat-284	292	45	an	an	DET
easat-284	292	46	overview	overview	NOUN
easat-284	292	47	,	,	PUNCT
easat-284	292	48	"	"	PUNCT
easat-284	292	49	frontiers	frontier	NOUN
easat-284	292	50	in	in	ADP
easat-284	292	51	immunology	immunology	NOUN
easat-284	292	52	,	,	PUNCT
easat-284	292	53	vol	vol	NOUN
easat-284	292	54	.	.	PROPN
easat-284	292	55	8	8	NUM
easat-284	292	56	,	,	PUNCT
easat-284	292	57	p.	p.	NOUN
easat-284	292	58	81	81	NUM
easat-284	292	59	,	,	PUNCT
easat-284	292	60	2017	2017	NUM
easat-284	292	61	.	.	PUNCT
easat-284	293	1	https://doi.org/10.3389/fimmu.2017.00081	https://doi.org/10.3389/fimmu.2017.00081	PROPN
easat-284	293	2	[	[	X
easat-284	293	3	34	34	NUM
easat-284	293	4	]	]	X
easat-284	293	5	y.	y.	NOUN
easat-284	293	6	zuo	zuo	PROPN
easat-284	293	7	et	et	PROPN
easat-284	293	8	al	al	PROPN
easat-284	293	9	.	.	PROPN
easat-284	293	10	,	,	PUNCT
easat-284	293	11	"	"	PUNCT
easat-284	293	12	neutrophil	neutrophil	ADJ
easat-284	293	13	extracellular	extracellular	ADJ
easat-284	293	14	traps	trap	NOUN
easat-284	293	15	in	in	ADP
easat-284	293	16	covid-19	covid-19	PROPN
easat-284	293	17	,	,	PUNCT
easat-284	293	18	"	"	PUNCT
easat-284	293	19	jci	jci	PROPN
easat-284	293	20	insight	insight	NOUN
easat-284	293	21	,	,	PUNCT
easat-284	293	22	vol	vol	NOUN
easat-284	293	23	.	.	PROPN
easat-284	293	24	5	5	NUM
easat-284	293	25	,	,	PUNCT
easat-284	293	26	no	no	INTJ
easat-284	293	27	.	.	NOUN
easat-284	293	28	11	11	NUM
easat-284	293	29	,	,	PUNCT
easat-284	293	30	2020	2020	NUM
easat-284	293	31	.	.	PUNCT
easat-284	294	1	[	[	X
easat-284	294	2	35	35	NUM
easat-284	294	3	]	]	X
easat-284	294	4	b.	b.	PROPN
easat-284	295	1	j.	j.	PROPN
easat-284	295	2	barnes	barnes	PROPN
easat-284	295	3	et	et	PROPN
easat-284	295	4	al	al	PROPN
easat-284	295	5	.	.	PROPN
easat-284	295	6	,	,	PUNCT
easat-284	295	7	"	"	PUNCT
easat-284	295	8	targeting	target	VERB
easat-284	295	9	potential	potential	ADJ
easat-284	295	10	drivers	driver	NOUN
easat-284	295	11	of	of	ADP
easat-284	295	12	covid-19	covid-19	PROPN
easat-284	295	13	:	:	PUNCT
easat-284	295	14	neutrophil	neutrophil	ADJ
easat-284	295	15	extracellular	extracellular	ADJ
easat-284	295	16	traps	trap	NOUN
easat-284	295	17	,	,	PUNCT
easat-284	295	18	"	"	PUNCT
easat-284	295	19	journal	journal	NOUN
easat-284	295	20	of	of	ADP
easat-284	295	21	experimental	experimental	ADJ
easat-284	295	22	medicine	medicine	NOUN
easat-284	295	23	,	,	PUNCT
easat-284	295	24	vol	vol	NOUN
easat-284	295	25	.	.	PROPN
easat-284	296	1	217	217	NUM
easat-284	296	2	,	,	PUNCT
easat-284	296	3	no	no	INTJ
easat-284	296	4	.	.	NOUN
easat-284	296	5	6	6	NUM
easat-284	296	6	,	,	PUNCT
easat-284	296	7	p.	p.	PROPN
easat-284	296	8	e20200652	e20200652	PROPN
easat-284	296	9	,	,	PUNCT
easat-284	296	10	2020	2020	NUM
easat-284	296	11	.	.	PUNCT
easat-284	297	1	[	[	X
easat-284	297	2	36	36	NUM
easat-284	297	3	]	]	X
easat-284	297	4	m.-l	m.-l	PROPN
easat-284	297	5	.	.	PUNCT
easat-284	298	1	von	von	PROPN
easat-284	298	2	brühl	brühl	PROPN
easat-284	298	3	et	et	PROPN
easat-284	298	4	al	al	PROPN
easat-284	298	5	.	.	PROPN
easat-284	298	6	,	,	PUNCT
easat-284	298	7	"	"	PUNCT
easat-284	298	8	monocytes	monocyte	NOUN
easat-284	298	9	,	,	PUNCT
easat-284	298	10	neutrophils	neutrophil	NOUN
easat-284	298	11	,	,	PUNCT
easat-284	298	12	and	and	CCONJ
easat-284	298	13	platelets	platelet	NOUN
easat-284	298	14	cooperate	cooperate	VERB
easat-284	298	15	to	to	PART
easat-284	298	16	initiate	initiate	VERB
easat-284	298	17	and	and	CCONJ
easat-284	298	18	propagate	propagate	VERB
easat-284	298	19	venous	venous	ADJ
easat-284	298	20	thrombosis	thrombosis	NOUN
easat-284	298	21	in	in	ADP
easat-284	298	22	mice	mouse	NOUN
easat-284	298	23	in	in	ADP
easat-284	298	24	vivo	vivo	NOUN
easat-284	298	25	,	,	PUNCT
easat-284	298	26	"	"	PUNCT
easat-284	298	27	journal	journal	NOUN
easat-284	298	28	of	of	ADP
easat-284	298	29	experimental	experimental	ADJ
easat-284	298	30	medicine	medicine	NOUN
easat-284	298	31	,	,	PUNCT
easat-284	298	32	vol	vol	NOUN
easat-284	298	33	.	.	PUNCT
easat-284	299	1	209	209	NUM
easat-284	299	2	,	,	PUNCT
easat-284	299	3	no	no	INTJ
easat-284	299	4	.	.	NOUN
easat-284	299	5	4	4	NUM
easat-284	299	6	,	,	PUNCT
easat-284	299	7	pp	pp	ADJ
easat-284	299	8	.	.	PUNCT
easat-284	299	9	819	819	NUM
easat-284	299	10	-	-	SYM
easat-284	299	11	835	835	NUM
easat-284	299	12	,	,	PUNCT
easat-284	299	13	2012	2012	NUM
easat-284	299	14	.	.	PUNCT
easat-284	300	1	https://doi.org/10.3410/f.14264125.15777262	https://doi.org/10.3410/f.14264125.15777262	X
easat-284	301	1	[	[	X
easat-284	301	2	37	37	NUM
easat-284	301	3	]	]	X
easat-284	301	4	n.	n.	PROPN
easat-284	301	5	varatharajah	varatharajah	PROPN
easat-284	301	6	and	and	CCONJ
easat-284	301	7	s.	s.	PROPN
easat-284	301	8	rajah	rajah	PROPN
easat-284	301	9	,	,	PUNCT
easat-284	301	10	"	"	PUNCT
easat-284	301	11	microthrombotic	microthrombotic	ADJ
easat-284	301	12	complications	complication	NOUN
easat-284	301	13	of	of	ADP
easat-284	301	14	covid-19	covid-19	PROPN
easat-284	301	15	are	be	AUX
easat-284	301	16	likely	likely	ADJ
easat-284	301	17	due	due	ADP
easat-284	301	18	to	to	ADP
easat-284	301	19	embolism	embolism	NOUN
easat-284	301	20	of	of	ADP
easat-284	301	21	circulating	circulate	VERB
easat-284	301	22	endothelial	endothelial	ADJ
easat-284	301	23	derived	derive	VERB
easat-284	301	24	ultralarge	ultralarge	NOUN
easat-284	301	25	von	von	PROPN
easat-284	301	26	willebrand	willebrand	PROPN
easat-284	301	27	factor	factor	NOUN
easat-284	301	28	(	(	PUNCT
easat-284	301	29	eulvwf	eulvwf	NOUN
easat-284	301	30	)	)	PUNCT
easat-284	301	31	decorated	decorate	VERB
easat-284	301	32	-	-	PUNCT
easat-284	301	33	platelet	platelet	NOUN
easat-284	301	34	strings	string	NOUN
easat-284	301	35	,	,	PUNCT
easat-284	301	36	"	"	PUNCT
easat-284	301	37	federal	federal	ADJ
easat-284	301	38	practitioner	practitioner	NOUN
easat-284	301	39	,	,	PUNCT
easat-284	301	40	vol	vol	NOUN
easat-284	301	41	.	.	PROPN
easat-284	301	42	37	37	NUM
easat-284	301	43	,	,	PUNCT
easat-284	301	44	no	no	INTJ
easat-284	301	45	.	.	NOUN
easat-284	301	46	6	6	NUM
easat-284	301	47	,	,	PUNCT
easat-284	301	48	p.	p.	NOUN
easat-284	301	49	258	258	NUM
easat-284	301	50	,	,	PUNCT
easat-284	301	51	2020	2020	NUM
easat-284	301	52	.	.	PUNCT
easat-284	302	1	[	[	X
easat-284	302	2	38	38	NUM
easat-284	302	3	]	]	PUNCT
easat-284	302	4	k.	k.	PROPN
easat-284	302	5	s.	s.	PROPN
easat-284	302	6	garland	garland	PROPN
easat-284	302	7	et	et	PROPN
easat-284	302	8	al	al	PROPN
easat-284	302	9	.	.	PROPN
easat-284	302	10	,	,	PUNCT
easat-284	302	11	"	"	PUNCT
easat-284	302	12	removal	removal	NOUN
easat-284	302	13	of	of	ADP
easat-284	302	14	the	the	DET
easat-284	302	15	c	c	NOUN
easat-284	302	16	-	-	PUNCT
easat-284	302	17	terminal	terminal	ADJ
easat-284	302	18	domains	domain	NOUN
easat-284	302	19	of	of	ADP
easat-284	302	20	adamts13	adamts13	NOUN
easat-284	302	21	by	by	ADP
easat-284	302	22	activated	activate	VERB
easat-284	302	23	coagulation	coagulation	NOUN
easat-284	302	24	factor	factor	NOUN
easat-284	302	25	xi	xi	NOUN
easat-284	302	26	induces	induce	VERB
easat-284	302	27	platelet	platelet	NOUN
easat-284	302	28	adhesion	adhesion	NOUN
easat-284	302	29	on	on	ADP
easat-284	302	30	endothelial	endothelial	ADJ
easat-284	302	31	cells	cell	NOUN
easat-284	302	32	under	under	ADP
easat-284	302	33	flow	flow	NOUN
easat-284	302	34	conditions	condition	NOUN
easat-284	302	35	,	,	PUNCT
easat-284	302	36	"	"	PUNCT
easat-284	302	37	frontiers	frontier	NOUN
easat-284	302	38	in	in	ADP
easat-284	302	39	medicine	medicine	NOUN
easat-284	302	40	,	,	PUNCT
easat-284	302	41	vol	vol	NOUN
easat-284	302	42	.	.	PROPN
easat-284	302	43	4	4	NUM
easat-284	302	44	,	,	PUNCT
easat-284	302	45	p.	p.	NOUN
easat-284	302	46	232	232	NUM
easat-284	302	47	,	,	PUNCT
easat-284	302	48	2017	2017	NUM
easat-284	302	49	.	.	PUNCT
easat-284	303	1	https://doi.org/10.3389/fmed.2017.00232	https://doi.org/10.3389/fmed.2017.00232	PROPN
easat-284	304	1	[	[	X
easat-284	304	2	39	39	NUM
easat-284	304	3	]	]	PUNCT
easat-284	304	4	v.	v.	ADP
easat-284	304	5	m.-l	m.-l	PROPN
easat-284	304	6	.	.	PUNCT
easat-284	305	1	bruehl	bruehl	NOUN
easat-284	305	2	et	et	PROPN
easat-284	305	3	al	al	PROPN
easat-284	305	4	.	.	PROPN
easat-284	305	5	,	,	PUNCT
easat-284	305	6	"	"	PUNCT
easat-284	305	7	reciprocal	reciprocal	ADJ
easat-284	305	8	coupling	coupling	NOUN
easat-284	305	9	of	of	ADP
easat-284	305	10	coagulation	coagulation	NOUN
easat-284	305	11	and	and	CCONJ
easat-284	305	12	innate	innate	ADJ
easat-284	305	13	immunity	immunity	NOUN
easat-284	305	14	via	via	ADP
easat-284	305	15	neutrophil	neutrophil	ADJ
easat-284	305	16	serine	serine	NOUN
easat-284	305	17	proteases	protease	NOUN
easat-284	305	18	,	,	PUNCT
easat-284	305	19	"	"	PUNCT
easat-284	305	20	nature	nature	NOUN
easat-284	305	21	medicine	medicine	NOUN
easat-284	305	22	,	,	PUNCT
easat-284	305	23	vol	vol	NOUN
easat-284	305	24	.	.	PROPN
easat-284	306	1	16	16	NUM
easat-284	306	2	,	,	PUNCT
easat-284	306	3	no	no	INTJ
easat-284	306	4	.	.	NOUN
easat-284	306	5	8	8	NUM
easat-284	306	6	,	,	PUNCT
easat-284	306	7	pp	pp	ADJ
easat-284	306	8	.	.	PUNCT
easat-284	307	1	887	887	NUM
easat-284	307	2	-	-	SYM
easat-284	307	3	896	896	NUM
easat-284	307	4	,	,	PUNCT
easat-284	307	5	2010	2010	NUM
easat-284	307	6	.	.	PUNCT
easat-284	308	1	https://doi.org/10.1038/nm.2184	https://doi.org/10.1038/nm.2184	VERB
easat-284	309	1	[	[	X
easat-284	309	2	40	40	NUM
easat-284	309	3	]	]	PUNCT
easat-284	309	4	j.	j.	PROPN
easat-284	309	5	c.	c.	PROPN
easat-284	309	6	chang	chang	PROPN
easat-284	309	7	,	,	PUNCT
easat-284	309	8	"	"	PUNCT
easat-284	309	9	ttp	ttp	NOUN
easat-284	309	10	-	-	PUNCT
easat-284	309	11	like	like	ADJ
easat-284	309	12	syndrome	syndrome	NOUN
easat-284	309	13	:	:	PUNCT
easat-284	309	14	novel	novel	ADJ
easat-284	309	15	concept	concept	NOUN
easat-284	309	16	and	and	CCONJ
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easat-284	309	18	pathogenesis	pathogenesis	NOUN
easat-284	309	19	of	of	ADP
easat-284	309	20	endotheliopathy	endotheliopathy	ADJ
easat-284	309	21	-associated	-associated	ADJ
easat-284	309	22	vascular	vascular	ADJ
easat-284	309	23	microthrombotic	microthrombotic	ADJ
easat-284	309	24	disease	disease	NOUN
easat-284	309	25	,	,	PUNCT
easat-284	309	26	"	"	PUNCT
easat-284	309	27	thrombosis	thrombosis	NOUN
easat-284	309	28	journal	journal	NOUN
easat-284	309	29	,	,	PUNCT
easat-284	309	30	vol	vol	NOUN
easat-284	309	31	.	.	PROPN
easat-284	309	32	16	16	NUM
easat-284	309	33	,	,	PUNCT
easat-284	309	34	no	no	INTJ
easat-284	309	35	.	.	NOUN
easat-284	309	36	1	1	NUM
easat-284	309	37	,	,	PUNCT
easat-284	309	38	pp	pp	ADJ
easat-284	309	39	.	.	PUNCT
easat-284	310	1	1	1	NUM
easat-284	310	2	-	-	SYM
easat-284	310	3	14	14	NUM
easat-284	310	4	,	,	PUNCT
easat-284	310	5	2018	2018	NUM
easat-284	310	6	.	.	PUNCT
easat-284	311	1	https://doi.org/10.1186/s12959-018-0174-4	https://doi.org/10.1186/s12959-018-0174-4	NUM
easat-284	312	1	[	[	X
easat-284	312	2	41	41	NUM
easat-284	312	3	]	]	X
easat-284	312	4	h.	h.	PROPN
easat-284	312	5	k.	k.	PROPN
easat-284	312	6	lehman	lehman	PROPN
easat-284	312	7	and	and	CCONJ
easat-284	312	8	b.	b.	PROPN
easat-284	312	9	h.	h.	PROPN
easat-284	312	10	segal	segal	PROPN
easat-284	312	11	,	,	PUNCT
easat-284	312	12	"	"	PUNCT
easat-284	312	13	the	the	DET
easat-284	312	14	role	role	NOUN
easat-284	312	15	of	of	ADP
easat-284	312	16	neutrophils	neutrophil	NOUN
easat-284	312	17	in	in	ADP
easat-284	312	18	host	host	NOUN
easat-284	312	19	defense	defense	NOUN
easat-284	312	20	and	and	CCONJ
easat-284	312	21	disease	disease	NOUN
easat-284	312	22	,	,	PUNCT
easat-284	312	23	"	"	PUNCT
easat-284	312	24	journal	journal	NOUN
easat-284	312	25	of	of	ADP
easat-284	312	26	allergy	allergy	NOUN
easat-284	312	27	and	and	CCONJ
easat-284	312	28	clinical	clinical	ADJ
easat-284	312	29	immunology	immunology	NOUN
easat-284	312	30	,	,	PUNCT
easat-284	312	31	vol	vol	NOUN
easat-284	312	32	.	.	PROPN
easat-284	312	33	145	145	NUM
easat-284	312	34	,	,	PUNCT
easat-284	312	35	no	no	INTJ
easat-284	312	36	.	.	NOUN
easat-284	312	37	6	6	NUM
easat-284	312	38	,	,	PUNCT
easat-284	312	39	pp	pp	ADJ
easat-284	312	40	.	.	PUNCT
easat-284	312	41	1535	1535	NUM
easat-284	312	42	-	-	SYM
easat-284	312	43	1544	1544	NUM
easat-284	312	44	,	,	PUNCT
easat-284	312	45	2020	2020	NUM
easat-284	312	46	.	.	PUNCT
easat-284	313	1	[	[	X
easat-284	313	2	42	42	NUM
easat-284	313	3	]	]	PUNCT
easat-284	313	4	a.	a.	NOUN
easat-284	313	5	bernardo	bernardo	PROPN
easat-284	313	6	,	,	PUNCT
easat-284	313	7	c.	c.	PROPN
easat-284	313	8	ball	ball	PROPN
easat-284	313	9	,	,	PUNCT
easat-284	313	10	l.	l.	PROPN
easat-284	313	11	nolasco	nolasco	PROPN
easat-284	313	12	,	,	PUNCT
easat-284	313	13	h.	h.	PROPN
easat-284	313	14	choi	choi	PROPN
easat-284	313	15	,	,	PUNCT
easat-284	313	16	j.	j.	PROPN
easat-284	313	17	moake	moake	PROPN
easat-284	313	18	,	,	PUNCT
easat-284	313	19	and	and	CCONJ
easat-284	313	20	j.	j.	PROPN
easat-284	313	21	dong	dong	PROPN
easat-284	313	22	,	,	PUNCT
easat-284	313	23	"	"	PUNCT
easat-284	313	24	platelets	platelet	NOUN
easat-284	313	25	adhered	adhere	VERB
easat-284	313	26	to	to	ADP
easat-284	313	27	endothelial	endothelial	ADJ
easat-284	313	28	cell	cell	NOUN
easat-284	313	29	-	-	PUNCT
easat-284	313	30	bound	bind	VERB
easat-284	313	31	ultra	ultra	ADJ
easat-284	313	32	-	-	ADJ
easat-284	313	33	large	large	ADJ
easat-284	313	34	von	von	PROPN
easat-284	313	35	willebrand	willebrand	NOUN
easat-284	313	36	factor	factor	NOUN
easat-284	313	37	strings	string	NOUN
easat-284	313	38	support	support	VERB
easat-284	313	39	leukocyte	leukocyte	NOUN
easat-284	313	40	tethering	tethering	NOUN
easat-284	313	41	and	and	CCONJ
easat-284	313	42	rolling	roll	VERB
easat-284	313	43	under	under	ADP
easat-284	313	44	high	high	ADJ
easat-284	313	45	shear	shear	NOUN
easat-284	313	46	stress	stress	NOUN
easat-284	313	47	,	,	PUNCT
easat-284	313	48	"	"	PUNCT
easat-284	313	49	journal	journal	NOUN
easat-284	313	50	of	of	ADP
easat-284	313	51	thrombosis	thrombosis	NOUN
easat-284	313	52	and	and	CCONJ
easat-284	313	53	haemostasis	haemostasis	NOUN
easat-284	313	54	,	,	PUNCT
easat-284	313	55	vol	vol	NOUN
easat-284	313	56	.	.	PROPN
easat-284	314	1	3	3	NUM
easat-284	314	2	,	,	PUNCT
easat-284	314	3	no	no	INTJ
easat-284	314	4	.	.	NOUN
easat-284	314	5	3	3	NUM
easat-284	314	6	,	,	PUNCT
easat-284	314	7	pp	pp	ADJ
easat-284	314	8	.	.	PUNCT
easat-284	315	1	562	562	NUM
easat-284	315	2	-	-	SYM
easat-284	315	3	570	570	NUM
easat-284	315	4	,	,	PUNCT
easat-284	315	5	2005	2005	NUM
easat-284	315	6	.	.	PUNCT
easat-284	316	1	https://doi.org/10.1111/j.1538-7836.2005.01122.x	https://doi.org/10.1111/j.1538-7836.2005.01122.x	PROPN
easat-284	316	2	https://doi.org/10.1128/jvi.00127-20	https://doi.org/10.1128/jvi.00127-20	PROPN
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easat-284	316	5	https://doi.org/10.1146/annurev-immunol-042718-041356	https://doi.org/10.1146/annurev-immunol-042718-041356	VERB
easat-284	316	6	https://doi.org/10.1101/2020.10.29.361048	https://doi.org/10.1101/2020.10.29.361048	PROPN
easat-284	316	7	https://doi.org/10.1016/j.cell.2020.04.026	https://doi.org/10.1016/j.cell.2020.04.026	PROPN
easat-284	316	8	https://doi.org/10.1093/cid/ciaa248	https://doi.org/10.1093/cid/ciaa248	NOUN
easat-284	316	9	https://doi.org/10.1016/j.ejcb.2006.12.003	https://doi.org/10.1016/j.ejcb.2006.12.003	NOUN
easat-284	316	10	https://doi.org/10.1074/jbc.m702615200	https://doi.org/10.1074/jbc.m702615200	X
easat-284	316	11	https://doi.org/10.1038/s41423-020-0450-7	https://doi.org/10.1038/s41423-020-0450-7	NUM
easat-284	316	12	https://doi.org/10.1016/j.cyto.2011.01.007	https://doi.org/10.1016/j.cyto.2011.01.007	VERB
easat-284	316	13	https://doi.org/10.3109/08923979709038538	https://doi.org/10.3109/08923979709038538	X
easat-284	316	14	https://doi.org/10.1084/jem.20110919	https://doi.org/10.1084/jem.20110919	PROPN
easat-284	316	15	https://doi.org/10.1183/13993003.00607-2020	https://doi.org/10.1183/13993003.00607-2020	X
easat-284	316	16	https://doi.org/10.1016/j.trsl.2020.04.007	https://doi.org/10.1016/j.trsl.2020.04.007	PROPN
easat-284	316	17	https://doi.org/10.1182/bloodadvances.2017011817	https://doi.org/10.1182/bloodadvances.2017011817	NOUN
easat-284	316	18	https://doi.org/10.1016/j.ijantimicag.2020.105954	https://doi.org/10.1016/j.ijantimicag.2020.105954	VERB
easat-284	316	19	https://doi.org/10.3389/fimmu.2017.00081	https://doi.org/10.3389/fimmu.2017.00081	PROPN
easat-284	316	20	https://doi.org/10.3410/f.14264125.15777262	https://doi.org/10.3410/f.14264125.15777262	X
easat-284	316	21	https://doi.org/10.3389/fmed.2017.00232	https://doi.org/10.3389/fmed.2017.00232	PROPN
easat-284	316	22	https://doi.org/10.1038/nm.2184	https://doi.org/10.1038/nm.2184	PROPN
easat-284	316	23	https://doi.org/10.1186/s12959-018-0174-4	https://doi.org/10.1186/s12959-018-0174-4	NUM
easat-284	317	1	https://doi.org/10.1111/j.1538-7836.2005.01122.x	https://doi.org/10.1111/j.1538-7836.2005.01122.x	ADJ
easat-284	317	2	73	73	NUM
easat-284	317	3	edelweiss	edelweiss	PROPN
easat-284	317	4	applied	apply	VERB
easat-284	317	5	science	science	NOUN
easat-284	317	6	and	and	CCONJ
easat-284	317	7	technology	technology	NOUN
easat-284	317	8	issn	issn	PROPN
easat-284	317	9	:	:	PUNCT
easat-284	317	10	2576	2576	NUM
easat-284	317	11	-	-	SYM
easat-284	317	12	8484	8484	NUM
easat-284	317	13	vol	vol	NOUN
easat-284	317	14	.	.	PROPN
easat-284	318	1	4	4	NUM
easat-284	318	2	,	,	PUNCT
easat-284	318	3	no	no	INTJ
easat-284	318	4	.	.	NOUN
easat-284	318	5	1	1	NUM
easat-284	318	6	:	:	SYM
easat-284	318	7	67	67	NUM
easat-284	318	8	-	-	SYM
easat-284	318	9	73	73	NUM
easat-284	318	10	,	,	PUNCT
easat-284	318	11	2020	2020	NUM
easat-284	318	12	doi	doi	NOUN
easat-284	318	13	:	:	PUNCT
easat-284	318	14	10.33805/2576	10.33805/2576	NUM
easat-284	318	15	-	-	SYM
easat-284	318	16	8484.184	8484.184	NUM
easat-284	318	17	©	©	PROPN
easat-284	318	18	2020	2020	NUM
easat-284	318	19	by	by	ADP
easat-284	318	20	the	the	DET
easat-284	318	21	author	author	NOUN
easat-284	318	22	[	[	X
easat-284	318	23	43	43	NUM
easat-284	318	24	]	]	X
easat-284	318	25	c.	c.	PROPN
easat-284	318	26	m.	m.	PROPN
easat-284	318	27	greene	greene	PROPN
easat-284	318	28	and	and	CCONJ
easat-284	318	29	n.	n.	PROPN
easat-284	318	30	g.	g.	PROPN
easat-284	318	31	mcelvaney	mcelvaney	PROPN
easat-284	318	32	,	,	PUNCT
easat-284	318	33	"	"	PUNCT
easat-284	318	34	proteases	protease	NOUN
easat-284	318	35	and	and	CCONJ
easat-284	318	36	antiproteases	antiprotease	NOUN
easat-284	318	37	in	in	ADP
easat-284	318	38	chronic	chronic	ADJ
easat-284	318	39	neutrophilic	neutrophilic	ADJ
easat-284	318	40	lung	lung	NOUN
easat-284	318	41	disease	disease	NOUN
easat-284	318	42	–	–	PUNCT
easat-284	318	43	relevance	relevance	NOUN
easat-284	318	44	to	to	ADP
easat-284	318	45	drug	drug	NOUN
easat-284	318	46	discovery	discovery	NOUN
easat-284	318	47	,	,	PUNCT
easat-284	318	48	"	"	PUNCT
easat-284	318	49	british	british	ADJ
easat-284	318	50	journal	journal	PROPN
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easat-284	318	52	pharmacology	pharmacology	NOUN
easat-284	318	53	,	,	PUNCT
easat-284	318	54	vol	vol	NOUN
easat-284	318	55	.	.	PROPN
easat-284	319	1	158	158	NUM
easat-284	319	2	,	,	PUNCT
easat-284	319	3	no	no	INTJ
easat-284	319	4	.	.	NOUN
easat-284	319	5	4	4	NUM
easat-284	319	6	,	,	PUNCT
easat-284	319	7	pp	pp	ADJ
easat-284	319	8	.	.	PUNCT
easat-284	320	1	1048	1048	NUM
easat-284	320	2	-	-	SYM
easat-284	320	3	1058	1058	NUM
easat-284	320	4	,	,	PUNCT
easat-284	320	5	2009	2009	NUM
easat-284	320	6	.	.	PUNCT
easat-284	321	1	https://doi.org/10.1111/j.14765381.2009.00448.x	https://doi.org/10.1111/j.14765381.2009.00448.x	X
easat-284	322	1	[	[	X
easat-284	322	2	44	44	NUM
easat-284	322	3	]	]	PUNCT
easat-284	322	4	d.	d.	PROPN
easat-284	322	5	e.	e.	PROPN
easat-284	322	6	cera	cera	PROPN
easat-284	322	7	,	,	PUNCT
easat-284	322	8	"	"	PUNCT
easat-284	322	9	serine	serine	NOUN
easat-284	322	10	proteases	protease	NOUN
easat-284	322	11	,	,	PUNCT
easat-284	322	12	"	"	PUNCT
easat-284	322	13	iubmb	iubmb	NOUN
easat-284	322	14	life	life	NOUN
easat-284	322	15	,	,	PUNCT
easat-284	322	16	vol	vol	NOUN
easat-284	322	17	.	.	PROPN
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easat-284	322	19	,	,	PUNCT
easat-284	322	20	no	no	INTJ
easat-284	322	21	.	.	NOUN
easat-284	322	22	5	5	NUM
easat-284	322	23	,	,	PUNCT
easat-284	322	24	pp	pp	ADJ
easat-284	322	25	.	.	PUNCT
easat-284	323	1	510	510	NUM
easat-284	323	2	-	-	SYM
easat-284	323	3	515	515	NUM
easat-284	323	4	,	,	PUNCT
easat-284	323	5	2009	2009	NUM
easat-284	323	6	.	.	PUNCT
easat-284	324	1	[	[	X
easat-284	324	2	45	45	NUM
easat-284	324	3	]	]	X
easat-284	324	4	g.	g.	PROPN
easat-284	324	5	thun	thun	PROPN
easat-284	324	6	,	,	PUNCT
easat-284	324	7	i.	i.	PROPN
easat-284	324	8	ferrarotti	ferrarotti	PROPN
easat-284	324	9	,	,	PUNCT
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easat-284	324	13	t.	t.	PROPN
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easat-284	324	15	,	,	PUNCT
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easat-284	324	17	m.	m.	NOUN
easat-284	324	18	gerbase	gerbase	PROPN
easat-284	324	19	,	,	PUNCT
easat-284	324	20	"	"	PUNCT
easat-284	324	21	serpina1	serpina1	X
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easat-284	324	23	and	and	CCONJ
easat-284	324	24	pis	pis	VERB
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easat-284	324	26	and	and	CCONJ
easat-284	324	27	lung	lung	NOUN
easat-284	324	28	function	function	NOUN
easat-284	324	29	decline	decline	NOUN
easat-284	324	30	in	in	ADP
easat-284	324	31	the	the	DET
easat-284	324	32	sapaldia	sapaldia	PROPN
easat-284	324	33	cohort	cohort	NOUN
easat-284	324	34	,	,	PUNCT
easat-284	324	35	"	"	PUNCT
easat-284	324	36	plos	plos	PROPN
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easat-284	324	38	,	,	PUNCT
easat-284	324	39	vol	vol	NOUN
easat-284	324	40	.	.	PROPN
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easat-284	324	42	,	,	PUNCT
easat-284	324	43	p.	p.	NOUN
easat-284	324	44	e42728	e42728	PROPN
easat-284	324	45	,	,	PUNCT
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easat-284	324	47	.	.	PUNCT
easat-284	325	1	[	[	X
easat-284	325	2	46	46	NUM
easat-284	325	3	]	]	PUNCT
easat-284	326	1	p.	p.	NOUN
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easat-284	327	9	extracellular	extracellular	ADJ
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easat-284	327	11	and	and	CCONJ
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easat-284	327	13	platelets	platelet	NOUN
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easat-284	327	15	procoagulant	procoagulant	NOUN
easat-284	327	16	activity	activity	NOUN
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easat-284	327	25	"	"	PUNCT
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easat-284	327	29	.	.	PROPN
easat-284	328	1	53	53	NUM
easat-284	328	2	,	,	PUNCT
easat-284	328	3	p.	p.	NOUN
easat-284	328	4	102671	102671	NUM
easat-284	328	5	,	,	PUNCT
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easat-284	328	7	.	.	PUNCT
easat-284	329	1	[	[	X
easat-284	329	2	47	47	NUM
easat-284	329	3	]	]	PUNCT
easat-284	329	4	j.	j.	PROPN
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easat-284	329	18	purpura	purpura	NOUN
easat-284	329	19	,	,	PUNCT
easat-284	329	20	"	"	PUNCT
easat-284	329	21	blood	blood	NOUN
easat-284	329	22	,	,	PUNCT
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easat-284	329	24	journal	journal	NOUN
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easat-284	329	26	the	the	DET
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easat-284	329	32	vol	vol	NOUN
easat-284	329	33	.	.	PROPN
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easat-284	330	2	,	,	PUNCT
easat-284	330	3	no	no	INTJ
easat-284	330	4	.	.	NOUN
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easat-284	330	6	,	,	PUNCT
easat-284	330	7	pp	pp	ADJ
easat-284	330	8	.	.	PUNCT
easat-284	331	1	2836	2836	NUM
easat-284	331	2	-	-	SYM
easat-284	331	3	2846	2846	NUM
easat-284	331	4	,	,	PUNCT
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easat-284	331	6	.	.	PUNCT
easat-284	332	1	[	[	X
easat-284	332	2	48	48	NUM
easat-284	332	3	]	]	PUNCT
easat-284	332	4	a.	a.	PROPN
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easat-284	332	11	a.	a.	PROPN
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easat-284	332	13	,	,	PUNCT
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easat-284	332	15	d.	d.	PROPN
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easat-284	332	20	,	,	PUNCT
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easat-284	332	43	,	,	PUNCT
easat-284	332	44	"	"	PUNCT
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easat-284	332	46	journal	journal	PROPN
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easat-284	332	51	.	.	PROPN
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easat-284	333	2	,	,	PUNCT
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easat-284	333	4	.	.	NOUN
easat-284	333	5	3	3	NUM
easat-284	333	6	,	,	PUNCT
easat-284	333	7	pp	pp	ADJ
easat-284	333	8	.	.	PUNCT
easat-284	334	1	733	733	NUM
easat-284	334	2	-	-	SYM
easat-284	334	3	739	739	NUM
easat-284	334	4	,	,	PUNCT
easat-284	334	5	1996	1996	NUM
easat-284	334	6	.	.	PUNCT
easat-284	335	1	https://doi.org/10.1046/j.1365-2141.1996.401939.x	https://doi.org/10.1046/j.1365-2141.1996.401939.x	PROPN
easat-284	336	1	[	[	X
easat-284	336	2	49	49	NUM
easat-284	336	3	]	]	PUNCT
easat-284	336	4	k.	k.	PROPN
easat-284	336	5	rajendran	rajendran	PROPN
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easat-284	336	7	n.	n.	PROPN
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easat-284	336	9	,	,	PUNCT
easat-284	336	10	j.	j.	PROPN
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easat-284	336	13	j.	j.	PROPN
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easat-284	336	15	,	,	PUNCT
easat-284	336	16	m.	m.	NOUN
easat-284	336	17	natarajan	natarajan	PROPN
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easat-284	336	20	a.	a.	NOUN
easat-284	336	21	ramachandran	ramachandran	PROPN
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easat-284	336	26	transfusion	transfusion	NOUN
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easat-284	336	28	the	the	DET
easat-284	336	29	treatment	treatment	NOUN
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easat-284	336	34	review	review	NOUN
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easat-284	336	36	"	"	PUNCT
easat-284	336	37	journal	journal	NOUN
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easat-284	336	40	virology	virology	NOUN
easat-284	336	41	,	,	PUNCT
easat-284	336	42	vol	vol	NOUN
easat-284	336	43	.	.	PROPN
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easat-284	337	2	,	,	PUNCT
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easat-284	337	4	.	.	NOUN
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easat-284	337	6	,	,	PUNCT
easat-284	337	7	pp	pp	ADJ
easat-284	337	8	.	.	PUNCT
easat-284	338	1	1475	1475	NUM
easat-284	338	2	-	-	SYM
easat-284	338	3	1483	1483	NUM
easat-284	338	4	,	,	PUNCT
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easat-284	338	6	.	.	PUNCT
easat-284	339	1	https://doi.org/10.1002/jmv.25961	https://doi.org/10.1002/jmv.25961	PROPN
easat-284	339	2	[	[	X
easat-284	339	3	50	50	NUM
easat-284	339	4	]	]	PUNCT
easat-284	339	5	k.	k.	NOUN
easat-284	339	6	chai	chai	PROPN
easat-284	339	7	,	,	PUNCT
easat-284	339	8	s.	s.	PROPN
easat-284	339	9	valk	valk	PROPN
easat-284	339	10	,	,	PUNCT
easat-284	339	11	v.	v.	ADP
easat-284	339	12	piechotta	piechotta	NOUN
easat-284	339	13	,	,	PUNCT
easat-284	339	14	c.	c.	PROPN
easat-284	339	15	kimber	kimber	PROPN
easat-284	339	16	,	,	PUNCT
easat-284	339	17	and	and	CCONJ
easat-284	339	18	i.	i.	PROPN
easat-284	339	19	monsef	monsef	PROPN
easat-284	339	20	,	,	PUNCT
easat-284	339	21	"	"	PUNCT
easat-284	339	22	convalescent	convalescent	NOUN
easat-284	339	23	plasma	plasma	NOUN
easat-284	339	24	or	or	CCONJ
easat-284	339	25	hyperimmune	hyperimmune	NOUN
easat-284	339	26	immunoglobulin	immunoglobulin	NOUN
easat-284	339	27	for	for	ADP
easat-284	339	28	people	people	NOUN
easat-284	339	29	with	with	ADP
easat-284	339	30	covid‐19	covid‐19	PROPN
easat-284	339	31	:	:	PUNCT
easat-284	339	32	a	a	DET
easat-284	339	33	living	live	VERB
easat-284	339	34	systematic	systematic	ADJ
easat-284	339	35	review	review	NOUN
easat-284	339	36	,	,	PUNCT
easat-284	339	37	"	"	PUNCT
easat-284	339	38	cochrane	cochrane	NOUN
easat-284	339	39	database	database	NOUN
easat-284	339	40	of	of	ADP
easat-284	339	41	systematic	systematic	ADJ
easat-284	339	42	reviews	review	NOUN
easat-284	339	43	,	,	PUNCT
easat-284	339	44	2020	2020	NUM
easat-284	339	45	.	.	PUNCT
easat-284	340	1	[	[	X
easat-284	340	2	51	51	NUM
easat-284	340	3	]	]	X
easat-284	340	4	v.	v.	ADP
easat-284	340	5	a.	a.	PROPN
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easat-284	340	14	trial	trial	NOUN
easat-284	340	15	of	of	ADP
easat-284	340	16	convalescent	convalescent	NOUN
easat-284	340	17	plasma	plasma	NOUN
easat-284	340	18	in	in	ADP
easat-284	340	19	covid-19	covid-19	PROPN
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easat-284	340	21	pneumonia	pneumonia	NOUN
easat-284	340	22	,	,	PUNCT
easat-284	340	23	"	"	PUNCT
easat-284	340	24	new	new	PROPN
easat-284	340	25	england	england	PROPN
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easat-284	340	27	of	of	ADP
easat-284	340	28	medicine	medicine	NOUN
easat-284	340	29	,	,	PUNCT
easat-284	340	30	vol	vol	NOUN
easat-284	340	31	.	.	PROPN
easat-284	340	32	384	384	NUM
easat-284	340	33	,	,	PUNCT
easat-284	340	34	no	no	INTJ
easat-284	340	35	.	.	NOUN
easat-284	340	36	7	7	NUM
easat-284	340	37	,	,	PUNCT
easat-284	340	38	pp	pp	ADJ
easat-284	340	39	.	.	PUNCT
easat-284	341	1	619	619	NUM
easat-284	341	2	-	-	SYM
easat-284	341	3	629	629	NUM
easat-284	341	4	,	,	PUNCT
easat-284	341	5	2021	2021	NUM
easat-284	341	6	.	.	PUNCT
easat-284	342	1	[	[	X
easat-284	342	2	52	52	NUM
easat-284	342	3	]	]	PUNCT
easat-284	342	4	r.	r.	PROPN
easat-284	342	5	j.	j.	PROPN
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easat-284	342	8	l.	l.	PROPN
easat-284	342	9	s.	s.	PROPN
easat-284	342	10	mclaughlin	mclaughlin	PROPN
easat-284	342	11	,	,	PUNCT
easat-284	342	12	"	"	PUNCT
easat-284	342	13	plasma	plasma	NOUN
easat-284	342	14	components	component	NOUN
easat-284	342	15	:	:	PUNCT
easat-284	342	16	properties	property	NOUN
easat-284	342	17	,	,	PUNCT
easat-284	342	18	differences	difference	NOUN
easat-284	342	19	,	,	PUNCT
easat-284	342	20	and	and	CCONJ
easat-284	342	21	uses	use	VERB
easat-284	342	22	,	,	PUNCT
easat-284	342	23	"	"	PUNCT
easat-284	342	24	transfusion	transfusion	NOUN
easat-284	342	25	,	,	PUNCT
easat-284	342	26	vol	vol	NOUN
easat-284	342	27	.	.	PROPN
easat-284	342	28	52	52	NUM
easat-284	342	29	,	,	PUNCT
easat-284	342	30	pp	pp	ADJ
easat-284	342	31	.	.	PUNCT
easat-284	343	1	9s19s	9s19s	NUM
easat-284	343	2	,	,	PUNCT
easat-284	343	3	2012	2012	NUM
easat-284	343	4	.	.	PUNCT
easat-284	344	1	https://doi.org/10.1111/j.1537-2995.2012.03622.x	https://doi.org/10.1111/j.1537-2995.2012.03622.x	PROPN
easat-284	345	1	[	[	X
easat-284	345	2	53	53	NUM
easat-284	345	3	]	]	X
easat-284	345	4	y.	y.	PROPN
easat-284	345	5	zhang	zhang	PROPN
easat-284	345	6	et	et	PROPN
easat-284	345	7	al	al	PROPN
easat-284	345	8	.	.	PROPN
easat-284	345	9	,	,	PUNCT
easat-284	345	10	"	"	PUNCT
easat-284	345	11	coagulopathy	coagulopathy	ADJ
easat-284	345	12	and	and	CCONJ
easat-284	345	13	antiphospholipid	antiphospholipid	NOUN
easat-284	345	14	antibodies	antibody	NOUN
easat-284	345	15	in	in	ADP
easat-284	345	16	patients	patient	NOUN
easat-284	345	17	with	with	ADP
easat-284	345	18	covid-19	covid-19	PROPN
easat-284	345	19	,	,	PUNCT
easat-284	345	20	"	"	PUNCT
easat-284	345	21	new	new	PROPN
easat-284	345	22	england	england	PROPN
easat-284	345	23	journal	journal	PROPN
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easat-284	345	26	,	,	PUNCT
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easat-284	345	28	.	.	PROPN
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easat-284	346	2	,	,	PUNCT
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easat-284	346	4	.	.	NOUN
easat-284	346	5	17	17	NUM
easat-284	346	6	,	,	PUNCT
easat-284	346	7	p.	p.	NOUN
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easat-284	346	9	,	,	PUNCT
easat-284	346	10	2020	2020	NUM
easat-284	346	11	.	.	PUNCT
easat-284	347	1	[	[	X
easat-284	347	2	54	54	NUM
easat-284	347	3	]	]	PUNCT
easat-284	347	4	l.	l.	PROPN
easat-284	347	5	e.	e.	PROPN
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easat-284	347	7	et	et	PROPN
easat-284	347	8	al	al	PROPN
easat-284	347	9	.	.	PROPN
easat-284	347	10	,	,	PUNCT
easat-284	347	11	"	"	PUNCT
easat-284	347	12	complement	complement	NOUN
easat-284	347	13	activation	activation	NOUN
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easat-284	347	15	to	to	ADP
easat-284	347	16	severe	severe	ADJ
easat-284	347	17	acute	acute	ADJ
easat-284	347	18	respiratory	respiratory	ADJ
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easat-284	347	21	pathogenesis	pathogenesis	NOUN
easat-284	347	22	,	,	PUNCT
easat-284	347	23	"	"	PUNCT
easat-284	347	24	mbio	mbio	NOUN
easat-284	347	25	,	,	PUNCT
easat-284	347	26	vol	vol	NOUN
easat-284	347	27	.	.	PROPN
easat-284	347	28	9	9	NUM
easat-284	347	29	,	,	PUNCT
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easat-284	347	31	.	.	NOUN
easat-284	347	32	5	5	NUM
easat-284	347	33	,	,	PUNCT
easat-284	347	34	pp	pp	ADJ
easat-284	347	35	.	.	PUNCT
easat-284	348	1	10.1128	10.1128	NUM
easat-284	348	2	/	/	SYM
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easat-284	348	4	.	.	PUNCT
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easat-284	349	2	-	-	SYM
easat-284	349	3	18	18	NUM
easat-284	349	4	,	,	PUNCT
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easat-284	349	6	.	.	PUNCT
easat-284	350	1	[	[	X
easat-284	350	2	55	55	NUM
easat-284	350	3	]	]	X
easat-284	350	4	c.	c.	PROPN
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easat-284	350	6	et	et	PROPN
easat-284	350	7	al	al	PROPN
easat-284	350	8	.	.	PROPN
easat-284	350	9	,	,	PUNCT
easat-284	350	10	"	"	PUNCT
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easat-284	350	12	type	type	NOUN
easat-284	350	13	2	2	NUM
easat-284	350	14	cdcs	cdc	NOUN
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easat-284	350	16	features	feature	NOUN
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easat-284	350	20	macrophages	macrophage	NOUN
easat-284	350	21	to	to	PART
easat-284	350	22	orchestrate	orchestrate	VERB
easat-284	350	23	immunity	immunity	NOUN
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easat-284	350	25	respiratory	respiratory	ADJ
easat-284	350	26	virus	virus	NOUN
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easat-284	350	28	,	,	PUNCT
easat-284	350	29	"	"	PUNCT
easat-284	350	30	immunity	immunity	NOUN
easat-284	350	31	,	,	PUNCT
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easat-284	350	41	.	.	PUNCT
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easat-284	350	43	-	-	SYM
easat-284	350	44	1056	1056	NUM
easat-284	350	45	.	.	PUNCT
easat-284	351	1	e9	e9	NOUN
easat-284	351	2	,	,	PUNCT
easat-284	351	3	2020	2020	NUM
easat-284	351	4	.	.	PUNCT
easat-284	352	1	[	[	X
easat-284	352	2	56	56	NUM
easat-284	352	3	]	]	PUNCT
easat-284	352	4	l.	l.	PROPN
easat-284	352	5	zhang	zhang	PROPN
easat-284	352	6	,	,	PUNCT
easat-284	352	7	d.	d.	PROPN
easat-284	352	8	lin	lin	PROPN
easat-284	352	9	,	,	PUNCT
easat-284	352	10	x.	x.	PROPN
easat-284	352	11	sun	sun	PROPN
easat-284	352	12	,	,	PUNCT
easat-284	352	13	u.	u.	PROPN
easat-284	352	14	curth	curth	PROPN
easat-284	352	15	,	,	PUNCT
easat-284	352	16	and	and	CCONJ
easat-284	352	17	c.	c.	PROPN
easat-284	352	18	drosten	drosten	PROPN
easat-284	352	19	,	,	PUNCT
easat-284	352	20	"	"	PUNCT
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easat-284	352	22	structure	structure	NOUN
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easat-284	352	24	sars	sar	NOUN
easat-284	352	25	-	-	PUNCT
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easat-284	352	27	main	main	ADJ
easat-284	352	28	protease	protease	NOUN
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easat-284	352	30	a	a	DET
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easat-284	352	37	-	-	PUNCT
easat-284	352	38	ketoamide	ketoamide	NOUN
easat-284	352	39	inhibitors	inhibitor	NOUN
easat-284	352	40	,	,	PUNCT
easat-284	352	41	"	"	PUNCT
easat-284	352	42	science	science	NOUN
easat-284	352	43	vol	vol	NOUN
easat-284	352	44	.	.	PROPN
easat-284	352	45	368	368	NUM
easat-284	352	46	,	,	PUNCT
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easat-284	353	2	-	-	SYM
easat-284	353	3	412	412	NUM
easat-284	353	4	,	,	PUNCT
easat-284	353	5	2020	2020	NUM
easat-284	353	6	.	.	PUNCT
easat-284	354	1	https://doi.org/10.1111/j.1476-5381.2009.00448.x	https://doi.org/10.1111/j.1476-5381.2009.00448.x	ADJ
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