id	sid	tid	token	lemma	pos
easat-4052	1	1	edelweiss	edelweiss	PROPN
easat-4052	1	2	applied	apply	VERB
easat-4052	1	3	science	science	NOUN
easat-4052	1	4	and	and	CCONJ
easat-4052	1	5	technology	technology	NOUN
easat-4052	1	6	issn	issn	PROPN
easat-4052	1	7	:	:	PUNCT
easat-4052	1	8	2576	2576	NUM
easat-4052	1	9	-	-	SYM
easat-4052	1	10	8484	8484	NUM
easat-4052	1	11	vol	vol	NOUN
easat-4052	1	12	.	.	PROPN
easat-4052	1	13	8	8	NUM
easat-4052	1	14	,	,	PUNCT
easat-4052	1	15	no	no	INTJ
easat-4052	1	16	.	.	NOUN
easat-4052	1	17	6	6	NUM
easat-4052	1	18	,	,	PUNCT
easat-4052	1	19	9592	9592	NUM
easat-4052	1	20	-	-	SYM
easat-4052	1	21	9604	9604	NUM
easat-4052	1	22	2024	2024	NUM
easat-4052	1	23	publisher	publisher	NOUN
easat-4052	1	24	:	:	PUNCT
easat-4052	1	25	learning	learn	VERB
easat-4052	1	26	gate	gate	PROPN
easat-4052	1	27	doi	doi	PROPN
easat-4052	1	28	:	:	PUNCT
easat-4052	1	29	10.55214/25768484.v8i6.4052	10.55214/25768484.v8i6.4052	PROPN
easat-4052	1	30	©	©	PROPN
easat-4052	1	31	2024	2024	NUM
easat-4052	1	32	by	by	ADP
easat-4052	1	33	the	the	DET
easat-4052	1	34	authors	author	NOUN
easat-4052	1	35	;	;	PUNCT
easat-4052	1	36	licensee	licensee	PROPN
easat-4052	1	37	learning	learning	NOUN
easat-4052	1	38	gate	gate	NOUN
easat-4052	1	39	©	©	PROPN
easat-4052	1	40	2024	2024	NUM
easat-4052	1	41	by	by	ADP
easat-4052	1	42	the	the	DET
easat-4052	1	43	authors	author	NOUN
easat-4052	1	44	;	;	PUNCT
easat-4052	1	45	licensee	licensee	PROPN
easat-4052	1	46	learning	learn	VERB
easat-4052	1	47	gate	gate	NOUN
easat-4052	1	48	*	*	PUNCT
easat-4052	1	49	correspondence	correspondence	NOUN
easat-4052	1	50	:	:	PUNCT
easat-4052	1	51	dwikora-novembri-u@fk.unair.ac.id	dwikora-novembri-u@fk.unair.ac.id	X
easat-4052	1	52	combination	combination	NOUN
easat-4052	1	53	of	of	ADP
easat-4052	1	54	scaffold	scaffold	NOUN
easat-4052	1	55	with	with	ADP
easat-4052	1	56	adipose	adipose	NOUN
easat-4052	1	57	-	-	PUNCT
easat-4052	1	58	derived	derive	VERB
easat-4052	1	59	mesenchymal	mesenchymal	NOUN
easat-4052	1	60	stem	stem	NOUN
easat-4052	1	61	cell	cell	NOUN
easat-4052	1	62	on	on	ADP
easat-4052	1	63	knee	knee	NOUN
easat-4052	1	64	joint	joint	ADJ
easat-4052	1	65	cartilage	cartilage	NOUN
easat-4052	1	66	defects	defect	NOUN
easat-4052	1	67	:	:	PUNCT
easat-4052	1	68	a	a	DET
easat-4052	1	69	literature	literature	NOUN
easat-4052	1	70	review	review	PROPN
easat-4052	1	71	aliefio	aliefio	PROPN
easat-4052	1	72	japamadisaw1,2	japamadisaw1,2	PROPN
easat-4052	1	73	,	,	PUNCT
easat-4052	1	74	kukuh	kukuh	PROPN
easat-4052	1	75	dwiputra	dwiputra	PROPN
easat-4052	1	76	hernugrahanto1,2	hernugrahanto1,2	PROPN
easat-4052	1	77	,	,	PUNCT
easat-4052	1	78	dwikora	dwikora	VERB
easat-4052	1	79	novembri	novembri	NOUN
easat-4052	1	80	utomo1,2	utomo1,2	PROPN
easat-4052	1	81	*	*	PROPN
easat-4052	1	82	1department	1department	NUM
easat-4052	1	83	of	of	ADP
easat-4052	1	84	orthopaedics	orthopaedic	NOUN
easat-4052	1	85	and	and	CCONJ
easat-4052	1	86	traumatology	traumatology	NOUN
easat-4052	1	87	,	,	PUNCT
easat-4052	1	88	faculty	faculty	NOUN
easat-4052	1	89	of	of	ADP
easat-4052	1	90	medicine	medicine	NOUN
easat-4052	1	91	airlangga	airlangga	PROPN
easat-4052	1	92	university	university	PROPN
easat-4052	1	93	,	,	PUNCT
easat-4052	1	94	surabaya	surabaya	PROPN
easat-4052	1	95	,	,	PUNCT
easat-4052	1	96	indonesia	indonesia	PROPN
easat-4052	1	97	;	;	PUNCT
easat-4052	1	98	aliefiojapamadisawlif@gmail.com	aliefiojapamadisawlif@gmail.com	PROPN
easat-4052	1	99	(	(	PUNCT
easat-4052	1	100	a.j	a.j	PROPN
easat-4052	1	101	.	.	PUNCT
easat-4052	1	102	)	)	PUNCT
easat-4052	2	1	kukuhdh@gmail.com	kukuhdh@gmail.com	X
easat-4052	2	2	(	(	PUNCT
easat-4052	2	3	k.d.h	k.d.h	PROPN
easat-4052	2	4	.	.	PUNCT
easat-4052	2	5	)	)	PUNCT
easat-4052	3	1	dwikora-novembri-u@fk.unair.ac.id	dwikora-novembri-u@fk.unair.ac.id	NOUN
easat-4052	3	2	(	(	PUNCT
easat-4052	3	3	d.n.u	d.n.u	PROPN
easat-4052	3	4	.	.	PUNCT
easat-4052	3	5	)	)	PUNCT
easat-4052	3	6	.	.	PUNCT
easat-4052	4	1	2department	2department	NUM
easat-4052	4	2	of	of	ADP
easat-4052	4	3	orthopaedics	orthopaedic	NOUN
easat-4052	4	4	and	and	CCONJ
easat-4052	4	5	traumatology	traumatology	NOUN
easat-4052	4	6	,	,	PUNCT
easat-4052	4	7	dr	dr	PROPN
easat-4052	4	8	.	.	PROPN
easat-4052	4	9	soetomo	soetomo	PROPN
easat-4052	4	10	general	general	PROPN
easat-4052	4	11	academic	academic	ADJ
easat-4052	4	12	hospital	hospital	NOUN
easat-4052	4	13	,	,	PUNCT
easat-4052	4	14	surabaya	surabaya	PROPN
easat-4052	4	15	,	,	PUNCT
easat-4052	4	16	indonesia	indonesia	PROPN
easat-4052	4	17	.	.	PUNCT
easat-4052	5	1	abstract	abstract	ADJ
easat-4052	5	2	:	:	PUNCT
easat-4052	5	3	knee	knee	NOUN
easat-4052	5	4	joint	joint	ADJ
easat-4052	5	5	cartilage	cartilage	NOUN
easat-4052	5	6	defects	defect	NOUN
easat-4052	5	7	are	be	AUX
easat-4052	5	8	a	a	DET
easat-4052	5	9	significant	significant	ADJ
easat-4052	5	10	clinical	clinical	ADJ
easat-4052	5	11	challenge	challenge	NOUN
easat-4052	5	12	due	due	ADP
easat-4052	5	13	to	to	ADP
easat-4052	5	14	the	the	DET
easat-4052	5	15	limited	limited	ADJ
easat-4052	5	16	regenerative	regenerative	ADJ
easat-4052	5	17	capacity	capacity	NOUN
easat-4052	5	18	of	of	ADP
easat-4052	5	19	articular	articular	ADJ
easat-4052	5	20	cartilage	cartilage	NOUN
easat-4052	5	21	,	,	PUNCT
easat-4052	5	22	often	often	ADV
easat-4052	5	23	leading	lead	VERB
easat-4052	5	24	to	to	ADP
easat-4052	5	25	joint	joint	ADJ
easat-4052	5	26	degeneration	degeneration	NOUN
easat-4052	5	27	and	and	CCONJ
easat-4052	5	28	osteoarthritis	osteoarthritis	NOUN
easat-4052	5	29	(	(	PUNCT
easat-4052	5	30	oa	oa	NOUN
easat-4052	5	31	)	)	PUNCT
easat-4052	5	32	.	.	PUNCT
easat-4052	6	1	conventional	conventional	ADJ
easat-4052	6	2	treatment	treatment	NOUN
easat-4052	6	3	methods	method	NOUN
easat-4052	6	4	,	,	PUNCT
easat-4052	6	5	such	such	ADJ
easat-4052	6	6	as	as	ADP
easat-4052	6	7	surgical	surgical	ADJ
easat-4052	6	8	repair	repair	NOUN
easat-4052	6	9	and	and	CCONJ
easat-4052	6	10	conservative	conservative	ADJ
easat-4052	6	11	management	management	NOUN
easat-4052	6	12	,	,	PUNCT
easat-4052	6	13	frequently	frequently	ADV
easat-4052	6	14	fail	fail	VERB
easat-4052	6	15	to	to	PART
easat-4052	6	16	restore	restore	VERB
easat-4052	6	17	cartilage	cartilage	NOUN
easat-4052	6	18	function	function	NOUN
easat-4052	6	19	fully	fully	ADV
easat-4052	6	20	.	.	PUNCT
easat-4052	7	1	in	in	ADP
easat-4052	7	2	recent	recent	ADJ
easat-4052	7	3	years	year	NOUN
easat-4052	7	4	,	,	PUNCT
easat-4052	7	5	scaffold	scaffold	NOUN
easat-4052	7	6	-	-	PUNCT
easat-4052	7	7	based	base	VERB
easat-4052	7	8	tissue	tissue	NOUN
easat-4052	7	9	engineering	engineering	NOUN
easat-4052	7	10	using	use	VERB
easat-4052	7	11	adipose	adipose	NOUN
easat-4052	7	12	-	-	PUNCT
easat-4052	7	13	derived	derive	VERB
easat-4052	7	14	mesenchymal	mesenchymal	NOUN
easat-4052	7	15	stem	stem	NOUN
easat-4052	7	16	cells	cell	NOUN
easat-4052	7	17	(	(	PUNCT
easat-4052	7	18	admscs	admscs	NOUN
easat-4052	7	19	)	)	PUNCT
easat-4052	7	20	has	have	AUX
easat-4052	7	21	emerged	emerge	VERB
easat-4052	7	22	as	as	ADP
easat-4052	7	23	a	a	DET
easat-4052	7	24	promising	promising	ADJ
easat-4052	7	25	strategy	strategy	NOUN
easat-4052	7	26	for	for	ADP
easat-4052	7	27	cartilage	cartilage	NOUN
easat-4052	7	28	regeneration	regeneration	NOUN
easat-4052	7	29	.	.	PUNCT
easat-4052	8	1	admscs	admscs	PROPN
easat-4052	8	2	,	,	PUNCT
easat-4052	8	3	known	know	VERB
easat-4052	8	4	for	for	ADP
easat-4052	8	5	their	their	PRON
easat-4052	8	6	abundant	abundant	ADJ
easat-4052	8	7	availability	availability	NOUN
easat-4052	8	8	,	,	PUNCT
easat-4052	8	9	ease	ease	NOUN
easat-4052	8	10	of	of	ADP
easat-4052	8	11	isolation	isolation	NOUN
easat-4052	8	12	,	,	PUNCT
easat-4052	8	13	and	and	CCONJ
easat-4052	8	14	chondrogenic	chondrogenic	ADJ
easat-4052	8	15	potential	potential	NOUN
easat-4052	8	16	,	,	PUNCT
easat-4052	8	17	provide	provide	VERB
easat-4052	8	18	a	a	DET
easat-4052	8	19	viable	viable	ADJ
easat-4052	8	20	cellular	cellular	ADJ
easat-4052	8	21	source	source	NOUN
easat-4052	8	22	for	for	ADP
easat-4052	8	23	repairing	repair	VERB
easat-4052	8	24	damaged	damage	VERB
easat-4052	8	25	cartilage	cartilage	NOUN
easat-4052	8	26	.	.	PUNCT
easat-4052	9	1	when	when	SCONJ
easat-4052	9	2	combined	combine	VERB
easat-4052	9	3	with	with	ADP
easat-4052	9	4	biocompatible	biocompatible	ADJ
easat-4052	9	5	scaffolds	scaffold	NOUN
easat-4052	9	6	,	,	PUNCT
easat-4052	9	7	admscs	admsc	NOUN
easat-4052	9	8	can	can	AUX
easat-4052	9	9	enhance	enhance	VERB
easat-4052	9	10	tissue	tissue	NOUN
easat-4052	9	11	regeneration	regeneration	NOUN
easat-4052	9	12	by	by	ADP
easat-4052	9	13	promoting	promote	VERB
easat-4052	9	14	cell	cell	NOUN
easat-4052	9	15	proliferation	proliferation	NOUN
easat-4052	9	16	,	,	PUNCT
easat-4052	9	17	differentiation	differentiation	NOUN
easat-4052	9	18	,	,	PUNCT
easat-4052	9	19	and	and	CCONJ
easat-4052	9	20	extracellular	extracellular	ADJ
easat-4052	9	21	matrix	matrix	NOUN
easat-4052	9	22	(	(	PUNCT
easat-4052	9	23	ecm	ecm	NOUN
easat-4052	9	24	)	)	PUNCT
easat-4052	9	25	formation	formation	NOUN
easat-4052	9	26	at	at	ADP
easat-4052	9	27	the	the	DET
easat-4052	9	28	injury	injury	NOUN
easat-4052	9	29	site	site	NOUN
easat-4052	9	30	.	.	PUNCT
easat-4052	10	1	various	various	ADJ
easat-4052	10	2	scaffold	scaffold	NOUN
easat-4052	10	3	materials	material	NOUN
easat-4052	10	4	,	,	PUNCT
easat-4052	10	5	including	include	VERB
easat-4052	10	6	natural	natural	ADJ
easat-4052	10	7	and	and	CCONJ
easat-4052	10	8	synthetic	synthetic	ADJ
easat-4052	10	9	polymers	polymer	NOUN
easat-4052	10	10	,	,	PUNCT
easat-4052	10	11	have	have	AUX
easat-4052	10	12	been	be	AUX
easat-4052	10	13	explored	explore	VERB
easat-4052	10	14	to	to	PART
easat-4052	10	15	provide	provide	VERB
easat-4052	10	16	the	the	DET
easat-4052	10	17	structural	structural	ADJ
easat-4052	10	18	support	support	NOUN
easat-4052	10	19	necessary	necessary	ADJ
easat-4052	10	20	for	for	ADP
easat-4052	10	21	cell	cell	NOUN
easat-4052	10	22	attachment	attachment	NOUN
easat-4052	10	23	and	and	CCONJ
easat-4052	10	24	tissue	tissue	NOUN
easat-4052	10	25	formation	formation	NOUN
easat-4052	10	26	.	.	PUNCT
easat-4052	11	1	this	this	DET
easat-4052	11	2	literature	literature	NOUN
easat-4052	11	3	review	review	NOUN
easat-4052	11	4	examines	examine	VERB
easat-4052	11	5	the	the	DET
easat-4052	11	6	current	current	ADJ
easat-4052	11	7	advancements	advancement	NOUN
easat-4052	11	8	in	in	ADP
easat-4052	11	9	the	the	DET
easat-4052	11	10	application	application	NOUN
easat-4052	11	11	of	of	ADP
easat-4052	11	12	admsc	admsc	NOUN
easat-4052	11	13	-	-	PUNCT
easat-4052	11	14	loaded	load	VERB
easat-4052	11	15	scaffolds	scaffold	NOUN
easat-4052	11	16	for	for	ADP
easat-4052	11	17	knee	knee	NOUN
easat-4052	11	18	joint	joint	ADJ
easat-4052	11	19	cartilage	cartilage	NOUN
easat-4052	11	20	defects	defect	NOUN
easat-4052	11	21	,	,	PUNCT
easat-4052	11	22	focusing	focus	VERB
easat-4052	11	23	on	on	ADP
easat-4052	11	24	their	their	PRON
easat-4052	11	25	biological	biological	ADJ
easat-4052	11	26	properties	property	NOUN
easat-4052	11	27	,	,	PUNCT
easat-4052	11	28	scaffold	scaffold	NOUN
easat-4052	11	29	designs	design	NOUN
easat-4052	11	30	,	,	PUNCT
easat-4052	11	31	and	and	CCONJ
easat-4052	11	32	the	the	DET
easat-4052	11	33	outcomes	outcome	NOUN
easat-4052	11	34	of	of	ADP
easat-4052	11	35	preclinical	preclinical	ADJ
easat-4052	11	36	and	and	CCONJ
easat-4052	11	37	clinical	clinical	ADJ
easat-4052	11	38	studies	study	NOUN
easat-4052	11	39	.	.	PUNCT
easat-4052	12	1	the	the	DET
easat-4052	12	2	review	review	NOUN
easat-4052	12	3	also	also	ADV
easat-4052	12	4	addresses	address	VERB
easat-4052	12	5	the	the	DET
easat-4052	12	6	challenges	challenge	NOUN
easat-4052	12	7	,	,	PUNCT
easat-4052	12	8	such	such	ADJ
easat-4052	12	9	as	as	ADP
easat-4052	12	10	scaffold	scaffold	NOUN
easat-4052	12	11	degradation	degradation	NOUN
easat-4052	12	12	,	,	PUNCT
easat-4052	12	13	mechanical	mechanical	ADJ
easat-4052	12	14	properties	property	NOUN
easat-4052	12	15	,	,	PUNCT
easat-4052	12	16	and	and	CCONJ
easat-4052	12	17	cellular	cellular	ADJ
easat-4052	12	18	migration	migration	NOUN
easat-4052	12	19	,	,	PUNCT
easat-4052	12	20	that	that	PRON
easat-4052	12	21	must	must	AUX
easat-4052	12	22	be	be	AUX
easat-4052	12	23	optimized	optimize	VERB
easat-4052	12	24	for	for	ADP
easat-4052	12	25	successful	successful	ADJ
easat-4052	12	26	clinical	clinical	ADJ
easat-4052	12	27	translation	translation	NOUN
easat-4052	12	28	.	.	PUNCT
easat-4052	13	1	overall	overall	ADV
easat-4052	13	2	,	,	PUNCT
easat-4052	13	3	this	this	DET
easat-4052	13	4	review	review	NOUN
easat-4052	13	5	highlights	highlight	VERB
easat-4052	13	6	the	the	DET
easat-4052	13	7	potential	potential	NOUN
easat-4052	13	8	of	of	ADP
easat-4052	13	9	admsc	admsc	NOUN
easat-4052	13	10	-	-	PUNCT
easat-4052	13	11	based	base	VERB
easat-4052	13	12	scaffold	scaffold	NOUN
easat-4052	13	13	systems	system	NOUN
easat-4052	13	14	to	to	PART
easat-4052	13	15	offer	offer	VERB
easat-4052	13	16	a	a	DET
easat-4052	13	17	viable	viable	ADJ
easat-4052	13	18	solution	solution	NOUN
easat-4052	13	19	for	for	ADP
easat-4052	13	20	knee	knee	NOUN
easat-4052	13	21	cartilage	cartilage	NOUN
easat-4052	13	22	repair	repair	NOUN
easat-4052	13	23	and	and	CCONJ
easat-4052	13	24	provides	provide	VERB
easat-4052	13	25	insights	insight	NOUN
easat-4052	13	26	into	into	ADP
easat-4052	13	27	future	future	ADJ
easat-4052	13	28	directions	direction	NOUN
easat-4052	13	29	for	for	ADP
easat-4052	13	30	improving	improve	VERB
easat-4052	13	31	therapeutic	therapeutic	ADJ
easat-4052	13	32	strategies	strategy	NOUN
easat-4052	13	33	in	in	ADP
easat-4052	13	34	cartilage	cartilage	NOUN
easat-4052	13	35	tissue	tissue	NOUN
easat-4052	13	36	engineering	engineering	NOUN
easat-4052	13	37	.	.	PUNCT
easat-4052	14	1	keywords	keyword	NOUN
easat-4052	14	2	:	:	PUNCT
easat-4052	14	3	adipose	adipose	NOUN
easat-4052	14	4	-	-	PUNCT
easat-4052	14	5	derived	derive	VERB
easat-4052	14	6	mesenchymal	mesenchymal	NOUN
easat-4052	14	7	stem	stem	NOUN
easat-4052	14	8	cells	cell	NOUN
easat-4052	14	9	,	,	PUNCT
easat-4052	14	10	knee	knee	NOUN
easat-4052	14	11	joint	joint	ADJ
easat-4052	14	12	cartilage	cartilage	NOUN
easat-4052	14	13	defects	defect	NOUN
easat-4052	14	14	,	,	PUNCT
easat-4052	14	15	literature	literature	NOUN
easat-4052	14	16	review	review	PROPN
easat-4052	14	17	,	,	PUNCT
easat-4052	14	18	regenerative	regenerative	ADJ
easat-4052	14	19	medicine	medicine	NOUN
easat-4052	14	20	,	,	PUNCT
easat-4052	14	21	tissue	tissue	NOUN
easat-4052	14	22	scaffold	scaffold	NOUN
easat-4052	14	23	.	.	PUNCT
easat-4052	15	1	1	1	X
easat-4052	15	2	.	.	X
easat-4052	15	3	introduction	introduction	NOUN
easat-4052	15	4	the	the	DET
easat-4052	15	5	knee	knee	NOUN
easat-4052	15	6	joint	joint	NOUN
easat-4052	15	7	,	,	PUNCT
easat-4052	15	8	owing	owe	VERB
easat-4052	15	9	to	to	ADP
easat-4052	15	10	its	its	PRON
easat-4052	15	11	anatomical	anatomical	ADJ
easat-4052	15	12	position	position	NOUN
easat-4052	15	13	and	and	CCONJ
easat-4052	15	14	complex	complex	ADJ
easat-4052	15	15	biomechanics	biomechanic	NOUN
easat-4052	15	16	,	,	PUNCT
easat-4052	15	17	is	be	AUX
easat-4052	15	18	particularly	particularly	ADV
easat-4052	15	19	prone	prone	ADJ
easat-4052	15	20	to	to	ADP
easat-4052	15	21	injury	injury	NOUN
easat-4052	15	22	[	[	X
easat-4052	15	23	1,2	1,2	NUM
easat-4052	15	24	]	]	PUNCT
easat-4052	15	25	.	.	PUNCT
easat-4052	16	1	patients	patient	NOUN
easat-4052	16	2	,	,	PUNCT
easat-4052	16	3	especially	especially	ADV
easat-4052	16	4	those	those	DET
easat-4052	16	5	over	over	ADP
easat-4052	16	6	40	40	NUM
easat-4052	16	7	years	year	NOUN
easat-4052	16	8	old	old	ADJ
easat-4052	16	9	and	and	CCONJ
easat-4052	16	10	athletes	athlete	NOUN
easat-4052	16	11	recovering	recover	VERB
easat-4052	16	12	from	from	ADP
easat-4052	16	13	traumatic	traumatic	ADJ
easat-4052	16	14	injuries	injury	NOUN
easat-4052	16	15	,	,	PUNCT
easat-4052	16	16	frequently	frequently	ADV
easat-4052	16	17	report	report	VERB
easat-4052	16	18	pain	pain	NOUN
easat-4052	16	19	in	in	ADP
easat-4052	16	20	this	this	DET
easat-4052	16	21	joint	joint	NOUN
easat-4052	16	22	,	,	PUNCT
easat-4052	16	23	primarily	primarily	ADV
easat-4052	16	24	in	in	ADP
easat-4052	16	25	the	the	DET
easat-4052	16	26	medial	medial	ADJ
easat-4052	16	27	compartment	compartment	NOUN
easat-4052	16	28	and	and	CCONJ
easat-4052	16	29	the	the	DET
easat-4052	16	30	patellofemoral	patellofemoral	ADJ
easat-4052	16	31	region	region	NOUN
easat-4052	16	32	.	.	PUNCT
easat-4052	17	1	these	these	DET
easat-4052	17	2	symptoms	symptom	NOUN
easat-4052	17	3	are	be	AUX
easat-4052	17	4	typically	typically	ADV
easat-4052	17	5	attributed	attribute	VERB
easat-4052	17	6	to	to	ADP
easat-4052	17	7	structural	structural	ADJ
easat-4052	17	8	alterations	alteration	NOUN
easat-4052	17	9	in	in	ADP
easat-4052	17	10	the	the	DET
easat-4052	17	11	articular	articular	ADJ
easat-4052	17	12	cartilage	cartilage	NOUN
easat-4052	17	13	,	,	PUNCT
easat-4052	17	14	potentially	potentially	ADV
easat-4052	17	15	leading	lead	VERB
easat-4052	17	16	to	to	ADP
easat-4052	17	17	osteoarthritis	osteoarthritis	NOUN
easat-4052	17	18	(	(	PUNCT
easat-4052	17	19	oa	oa	INTJ
easat-4052	17	20	)	)	PUNCT
easat-4052	18	1	[	[	X
easat-4052	18	2	2	2	NUM
easat-4052	18	3	]	]	PUNCT
easat-4052	18	4	.	.	PUNCT
easat-4052	19	1	cartilage	cartilage	NOUN
easat-4052	19	2	damage	damage	NOUN
easat-4052	19	3	in	in	ADP
easat-4052	19	4	major	major	ADJ
easat-4052	19	5	joints	joint	NOUN
easat-4052	19	6	is	be	AUX
easat-4052	19	7	a	a	DET
easat-4052	19	8	frequent	frequent	ADJ
easat-4052	19	9	occurrence	occurrence	NOUN
easat-4052	19	10	and	and	CCONJ
easat-4052	19	11	may	may	AUX
easat-4052	19	12	present	present	VERB
easat-4052	19	13	as	as	ADP
easat-4052	19	14	an	an	DET
easat-4052	19	15	isolated	isolated	ADJ
easat-4052	19	16	issue	issue	NOUN
easat-4052	19	17	or	or	CCONJ
easat-4052	19	18	in	in	ADP
easat-4052	19	19	conjunction	conjunction	NOUN
easat-4052	19	20	with	with	ADP
easat-4052	19	21	bone	bone	NOUN
easat-4052	19	22	defects	defect	NOUN
easat-4052	19	23	,	,	PUNCT
easat-4052	19	24	ligament	ligament	NOUN
easat-4052	19	25	injuries	injury	NOUN
easat-4052	19	26	,	,	PUNCT
easat-4052	19	27	limb	limb	NOUN
easat-4052	19	28	misalignment	misalignment	NOUN
easat-4052	19	29	,	,	PUNCT
easat-4052	19	30	or	or	CCONJ
easat-4052	19	31	associated	associate	VERB
easat-4052	19	32	traumatic	traumatic	ADJ
easat-4052	19	33	injuries	injury	NOUN
easat-4052	19	34	[	[	X
easat-4052	19	35	1	1	NUM
easat-4052	19	36	]	]	PUNCT
easat-4052	19	37	.	.	PUNCT
easat-4052	20	1	cartilage	cartilage	NOUN
easat-4052	20	2	,	,	PUNCT
easat-4052	20	3	particularly	particularly	ADV
easat-4052	20	4	articular	articular	ADJ
easat-4052	20	5	cartilage	cartilage	NOUN
easat-4052	20	6	,	,	PUNCT
easat-4052	20	7	is	be	AUX
easat-4052	20	8	a	a	DET
easat-4052	20	9	specialized	specialized	ADJ
easat-4052	20	10	connective	connective	ADJ
easat-4052	20	11	tissue	tissue	NOUN
easat-4052	20	12	of	of	ADP
easat-4052	20	13	chondrocytes	chondrocyte	NOUN
easat-4052	20	14	embedded	embed	VERB
easat-4052	20	15	within	within	ADP
easat-4052	20	16	an	an	DET
easat-4052	20	17	extracellular	extracellular	ADJ
easat-4052	20	18	cartilage	cartilage	NOUN
easat-4052	20	19	matrix	matrix	NOUN
easat-4052	20	20	.	.	PUNCT
easat-4052	21	1	this	this	DET
easat-4052	21	2	tissue	tissue	NOUN
easat-4052	21	3	is	be	AUX
easat-4052	21	4	vital	vital	ADJ
easat-4052	21	5	in	in	ADP
easat-4052	21	6	joint	joint	ADJ
easat-4052	21	7	mechanics	mechanic	NOUN
easat-4052	21	8	,	,	PUNCT
easat-4052	21	9	ensuring	ensure	VERB
easat-4052	21	10	durability	durability	NOUN
easat-4052	21	11	and	and	CCONJ
easat-4052	21	12	mobility	mobility	NOUN
easat-4052	21	13	by	by	ADP
easat-4052	21	14	facilitating	facilitate	VERB
easat-4052	21	15	nearly	nearly	ADV
easat-4052	21	16	frictionless	frictionless	ADJ
easat-4052	21	17	movement	movement	NOUN
easat-4052	21	18	and	and	CCONJ
easat-4052	21	19	enabling	enable	VERB
easat-4052	21	20	efficient	efficient	ADJ
easat-4052	21	21	transmission	transmission	NOUN
easat-4052	21	22	of	of	ADP
easat-4052	21	23	mechanical	mechanical	ADJ
easat-4052	21	24	loads	load	NOUN
easat-4052	21	25	across	across	ADP
easat-4052	21	26	joint	joint	ADJ
easat-4052	21	27	surfaces	surface	NOUN
easat-4052	21	28	[	[	X
easat-4052	21	29	2–4	2–4	NUM
easat-4052	21	30	]	]	PUNCT
easat-4052	21	31	.	.	PUNCT
easat-4052	22	1	its	its	PRON
easat-4052	22	2	lack	lack	NOUN
easat-4052	22	3	of	of	ADP
easat-4052	22	4	vascularization	vascularization	NOUN
easat-4052	22	5	and	and	CCONJ
easat-4052	22	6	limited	limited	ADJ
easat-4052	22	7	cellularity	cellularity	NOUN
easat-4052	22	8	contribute	contribute	VERB
easat-4052	22	9	to	to	ADP
easat-4052	22	10	a	a	DET
easat-4052	22	11	poor	poor	ADJ
easat-4052	22	12	intrinsic	intrinsic	ADJ
easat-4052	22	13	capacity	capacity	NOUN
easat-4052	22	14	for	for	ADP
easat-4052	22	15	self	self	NOUN
easat-4052	22	16	-	-	PUNCT
easat-4052	22	17	repair	repair	NOUN
easat-4052	22	18	.	.	PUNCT
easat-4052	23	1	furthermore	furthermore	ADV
easat-4052	23	2	,	,	PUNCT
easat-4052	23	3	the	the	DET
easat-4052	23	4	dense	dense	ADJ
easat-4052	23	5	,	,	PUNCT
easat-4052	23	6	threedimensional	threedimensional	ADJ
easat-4052	23	7	structure	structure	NOUN
easat-4052	23	8	of	of	ADP
easat-4052	23	9	the	the	DET
easat-4052	23	10	ecm	ecm	PROPN
easat-4052	23	11	impedes	impede	VERB
easat-4052	23	12	stem	stem	NOUN
easat-4052	23	13	cell	cell	NOUN
easat-4052	23	14	migration	migration	NOUN
easat-4052	23	15	,	,	PUNCT
easat-4052	23	16	hindering	hinder	VERB
easat-4052	23	17	cartilage	cartilage	NOUN
easat-4052	23	18	regeneration	regeneration	NOUN
easat-4052	23	19	[	[	X
easat-4052	23	20	3	3	NUM
easat-4052	23	21	]	]	PUNCT
easat-4052	23	22	.	.	PUNCT
easat-4052	24	1	in	in	ADP
easat-4052	24	2	general	general	ADJ
easat-4052	24	3	,	,	PUNCT
easat-4052	24	4	articular	articular	ADJ
easat-4052	24	5	cartilage	cartilage	NOUN
easat-4052	24	6	injuries	injury	NOUN
easat-4052	24	7	are	be	AUX
easat-4052	24	8	identified	identify	VERB
easat-4052	24	9	in	in	ADP
easat-4052	24	10	34–62	34–62	NUM
easat-4052	24	11	%	%	NOUN
easat-4052	24	12	of	of	ADP
easat-4052	24	13	knees	knee	NOUN
easat-4052	24	14	during	during	ADP
easat-4052	24	15	arthroscopic	arthroscopic	ADJ
easat-4052	24	16	procedures	procedure	NOUN
easat-4052	24	17	[	[	X
easat-4052	24	18	2,3	2,3	NUM
easat-4052	24	19	]	]	PUNCT
easat-4052	24	20	.	.	PUNCT
easat-4052	25	1	https://orcid.org/0009-0001-3021-7986	https://orcid.org/0009-0001-3021-7986	PROPN
easat-4052	25	2	https://orcid.org/0000-0002-6664-4920	https://orcid.org/0000-0002-6664-4920	PROPN
easat-4052	25	3	9593	9593	NUM
easat-4052	25	4	edelweiss	edelweiss	PROPN
easat-4052	25	5	applied	apply	VERB
easat-4052	25	6	science	science	NOUN
easat-4052	25	7	and	and	CCONJ
easat-4052	25	8	technology	technology	NOUN
easat-4052	25	9	issn	issn	PROPN
easat-4052	25	10	:	:	PUNCT
easat-4052	25	11	2576	2576	NUM
easat-4052	25	12	-	-	SYM
easat-4052	25	13	8484	8484	NUM
easat-4052	25	14	vol	vol	NOUN
easat-4052	25	15	.	.	PROPN
easat-4052	25	16	8	8	NUM
easat-4052	25	17	,	,	PUNCT
easat-4052	25	18	no	no	INTJ
easat-4052	25	19	.	.	NOUN
easat-4052	26	1	6	6	NUM
easat-4052	26	2	:	:	SYM
easat-4052	26	3	9592	9592	NUM
easat-4052	26	4	-	-	SYM
easat-4052	26	5	9604	9604	NUM
easat-4052	26	6	,	,	PUNCT
easat-4052	26	7	2024	2024	NUM
easat-4052	26	8	doi	doi	NOUN
easat-4052	26	9	:	:	PUNCT
easat-4052	26	10	10.55214/25768484.v8i6.4052	10.55214/25768484.v8i6.4052	NUM
easat-4052	27	1	©	©	ADP
easat-4052	27	2	2024	2024	NUM
easat-4052	27	3	by	by	ADP
easat-4052	27	4	the	the	DET
easat-4052	27	5	authors	author	NOUN
easat-4052	27	6	;	;	PUNCT
easat-4052	27	7	licensee	licensee	PROPN
easat-4052	27	8	learning	learn	VERB
easat-4052	27	9	gate	gate	PROPN
easat-4052	27	10	nonoperative	nonoperative	ADJ
easat-4052	27	11	management	management	NOUN
easat-4052	27	12	is	be	AUX
easat-4052	27	13	typically	typically	ADV
easat-4052	27	14	the	the	DET
easat-4052	27	15	first	first	ADJ
easat-4052	27	16	-	-	PUNCT
easat-4052	27	17	line	line	NOUN
easat-4052	27	18	approach	approach	NOUN
easat-4052	27	19	for	for	ADP
easat-4052	27	20	focal	focal	ADJ
easat-4052	27	21	cartilage	cartilage	NOUN
easat-4052	27	22	lesions	lesion	NOUN
easat-4052	27	23	;	;	PUNCT
easat-4052	27	24	however	however	ADV
easat-4052	27	25	,	,	PUNCT
easat-4052	27	26	up	up	ADP
easat-4052	27	27	to	to	PART
easat-4052	27	28	90	90	NUM
easat-4052	27	29	%	%	NOUN
easat-4052	27	30	of	of	ADP
easat-4052	27	31	patients	patient	NOUN
easat-4052	27	32	undergoing	undergo	VERB
easat-4052	27	33	conservative	conservative	ADJ
easat-4052	27	34	treatment	treatment	NOUN
easat-4052	27	35	continue	continue	VERB
easat-4052	27	36	to	to	PART
easat-4052	27	37	experience	experience	VERB
easat-4052	27	38	pain	pain	NOUN
easat-4052	27	39	and	and	CCONJ
easat-4052	27	40	mechanical	mechanical	ADJ
easat-4052	27	41	symptoms	symptom	NOUN
easat-4052	27	42	,	,	PUNCT
easat-4052	27	43	often	often	ADV
easat-4052	27	44	necessitating	necessitate	VERB
easat-4052	27	45	surgical	surgical	ADJ
easat-4052	27	46	intervention	intervention	NOUN
easat-4052	27	47	[	[	X
easat-4052	27	48	5	5	NUM
easat-4052	27	49	]	]	PUNCT
easat-4052	27	50	.	.	PUNCT
easat-4052	28	1	surgical	surgical	ADJ
easat-4052	28	2	options	option	NOUN
easat-4052	28	3	are	be	AUX
easat-4052	28	4	guided	guide	VERB
easat-4052	28	5	by	by	ADP
easat-4052	28	6	factors	factor	NOUN
easat-4052	28	7	such	such	ADJ
easat-4052	28	8	as	as	ADP
easat-4052	28	9	the	the	DET
easat-4052	28	10	size	size	NOUN
easat-4052	28	11	and	and	CCONJ
easat-4052	28	12	severity	severity	NOUN
easat-4052	28	13	of	of	ADP
easat-4052	28	14	the	the	DET
easat-4052	28	15	defect	defect	NOUN
easat-4052	28	16	,	,	PUNCT
easat-4052	28	17	adherence	adherence	NOUN
easat-4052	28	18	to	to	ADP
easat-4052	28	19	postoperative	postoperative	ADJ
easat-4052	28	20	rehabilitation	rehabilitation	NOUN
easat-4052	28	21	protocols	protocol	NOUN
easat-4052	28	22	,	,	PUNCT
easat-4052	28	23	weight	weight	NOUN
easat-4052	28	24	-	-	PUNCT
easat-4052	28	25	bearing	bear	VERB
easat-4052	28	26	limitations	limitation	NOUN
easat-4052	28	27	,	,	PUNCT
easat-4052	28	28	and	and	CCONJ
easat-4052	28	29	the	the	DET
easat-4052	28	30	patient	patient	NOUN
easat-4052	28	31	’s	’s	PART
easat-4052	28	32	goals	goal	NOUN
easat-4052	28	33	and	and	CCONJ
easat-4052	28	34	expectations	expectation	NOUN
easat-4052	28	35	[	[	X
easat-4052	28	36	5,6	5,6	NUM
easat-4052	28	37	]	]	X
easat-4052	28	38	.	.	PUNCT
easat-4052	29	1	nevertheless	nevertheless	ADV
easat-4052	29	2	,	,	PUNCT
easat-4052	29	3	these	these	DET
easat-4052	29	4	two	two	NUM
easat-4052	29	5	therapeutic	therapeutic	ADJ
easat-4052	29	6	modalities	modality	NOUN
easat-4052	29	7	frequently	frequently	ADV
easat-4052	29	8	fail	fail	VERB
easat-4052	29	9	to	to	PART
easat-4052	29	10	restore	restore	VERB
easat-4052	29	11	the	the	DET
easat-4052	29	12	native	native	ADJ
easat-4052	29	13	structure	structure	NOUN
easat-4052	29	14	and	and	CCONJ
easat-4052	29	15	function	function	NOUN
easat-4052	29	16	of	of	ADP
easat-4052	29	17	the	the	DET
easat-4052	29	18	damaged	damage	VERB
easat-4052	29	19	cartilage	cartilage	NOUN
easat-4052	29	20	,	,	PUNCT
easat-4052	29	21	driving	drive	VERB
easat-4052	29	22	the	the	DET
easat-4052	29	23	need	need	NOUN
easat-4052	29	24	for	for	ADP
easat-4052	29	25	advanced	advanced	ADJ
easat-4052	29	26	regenerative	regenerative	ADJ
easat-4052	29	27	strategies	strategy	NOUN
easat-4052	29	28	[	[	X
easat-4052	29	29	7	7	NUM
easat-4052	29	30	]	]	PUNCT
easat-4052	29	31	.	.	PUNCT
easat-4052	30	1	cell	cell	NOUN
easat-4052	30	2	-	-	PUNCT
easat-4052	30	3	based	base	VERB
easat-4052	30	4	therapy	therapy	NOUN
easat-4052	30	5	has	have	AUX
easat-4052	30	6	garnered	garner	VERB
easat-4052	30	7	significant	significant	ADJ
easat-4052	30	8	attention	attention	NOUN
easat-4052	30	9	over	over	ADP
easat-4052	30	10	the	the	DET
easat-4052	30	11	past	past	ADJ
easat-4052	30	12	decades	decade	NOUN
easat-4052	30	13	,	,	PUNCT
easat-4052	30	14	offering	offer	VERB
easat-4052	30	15	promising	promising	ADJ
easat-4052	30	16	potential	potential	NOUN
easat-4052	30	17	to	to	PART
easat-4052	30	18	revolutionize	revolutionize	VERB
easat-4052	30	19	the	the	DET
easat-4052	30	20	treatment	treatment	NOUN
easat-4052	30	21	of	of	ADP
easat-4052	30	22	various	various	ADJ
easat-4052	30	23	injuries	injury	NOUN
easat-4052	30	24	and	and	CCONJ
easat-4052	30	25	diseases	disease	NOUN
easat-4052	30	26	[	[	X
easat-4052	30	27	8,9	8,9	NUM
easat-4052	30	28	]	]	PUNCT
easat-4052	30	29	.	.	PUNCT
easat-4052	31	1	the	the	DET
easat-4052	31	2	differentiation	differentiation	NOUN
easat-4052	31	3	of	of	ADP
easat-4052	31	4	mesenchymal	mesenchymal	ADJ
easat-4052	31	5	stromal	stromal	ADJ
easat-4052	31	6	cells	cell	NOUN
easat-4052	31	7	(	(	PUNCT
easat-4052	31	8	mscs	msc	NOUN
easat-4052	31	9	)	)	PUNCT
easat-4052	31	10	into	into	ADP
easat-4052	31	11	chondrocytes	chondrocyte	NOUN
easat-4052	31	12	has	have	AUX
easat-4052	31	13	been	be	AUX
easat-4052	31	14	extensively	extensively	ADV
easat-4052	31	15	studied	study	VERB
easat-4052	31	16	,	,	PUNCT
easat-4052	31	17	resulting	result	VERB
easat-4052	31	18	in	in	ADP
easat-4052	31	19	cartilaginous	cartilaginous	ADJ
easat-4052	31	20	tissue	tissue	NOUN
easat-4052	31	21	formation	formation	NOUN
easat-4052	31	22	in	in	ADP
easat-4052	31	23	laboratory	laboratory	NOUN
easat-4052	31	24	experiments	experiment	NOUN
easat-4052	31	25	,	,	PUNCT
easat-4052	31	26	mscs	msc	NOUN
easat-4052	31	27	have	have	AUX
easat-4052	31	28	demonstrated	demonstrate	VERB
easat-4052	31	29	the	the	DET
easat-4052	31	30	ability	ability	NOUN
easat-4052	31	31	to	to	PART
easat-4052	31	32	generate	generate	VERB
easat-4052	31	33	cartilage	cartilage	NOUN
easat-4052	31	34	-	-	PUNCT
easat-4052	31	35	like	like	ADJ
easat-4052	31	36	tissue	tissue	NOUN
easat-4052	31	37	when	when	SCONJ
easat-4052	31	38	cultured	cultured	ADJ
easat-4052	31	39	with	with	ADP
easat-4052	31	40	the	the	DET
easat-4052	31	41	appropriate	appropriate	ADJ
easat-4052	31	42	growth	growth	NOUN
easat-4052	31	43	factors	factor	NOUN
easat-4052	31	44	and	and	CCONJ
easat-4052	31	45	scaffolds	scaffold	NOUN
easat-4052	31	46	,	,	PUNCT
easat-4052	31	47	highlighting	highlight	VERB
easat-4052	31	48	their	their	PRON
easat-4052	31	49	potential	potential	NOUN
easat-4052	31	50	in	in	ADP
easat-4052	31	51	cartilage	cartilage	NOUN
easat-4052	31	52	repair	repair	NOUN
easat-4052	31	53	and	and	CCONJ
easat-4052	31	54	regeneration	regeneration	NOUN
easat-4052	31	55	[	[	X
easat-4052	31	56	10	10	NUM
easat-4052	31	57	]	]	PUNCT
easat-4052	31	58	.	.	PUNCT
easat-4052	32	1	in	in	ADP
easat-4052	32	2	both	both	PRON
easat-4052	32	3	in	in	ADP
easat-4052	32	4	vivo	vivo	NOUN
easat-4052	32	5	and	and	CCONJ
easat-4052	32	6	in	in	ADP
easat-4052	32	7	vitro	vitro	X
easat-4052	32	8	studies	study	NOUN
easat-4052	32	9	,	,	PUNCT
easat-4052	32	10	adipose	adipose	NOUN
easat-4052	32	11	-	-	PUNCT
easat-4052	32	12	derived	derive	VERB
easat-4052	32	13	mesenchymal	mesenchymal	NOUN
easat-4052	32	14	stem	stem	NOUN
easat-4052	32	15	cells	cell	NOUN
easat-4052	32	16	(	(	PUNCT
easat-4052	32	17	admscs	admscs	ADV
easat-4052	32	18	)	)	PUNCT
easat-4052	32	19	have	have	AUX
easat-4052	32	20	demonstrated	demonstrate	VERB
easat-4052	32	21	the	the	DET
easat-4052	32	22	potential	potential	NOUN
easat-4052	32	23	to	to	PART
easat-4052	32	24	differentiate	differentiate	VERB
easat-4052	32	25	into	into	ADP
easat-4052	32	26	a	a	DET
easat-4052	32	27	variety	variety	NOUN
easat-4052	32	28	of	of	ADP
easat-4052	32	29	cell	cell	NOUN
easat-4052	32	30	types	type	NOUN
easat-4052	32	31	,	,	PUNCT
easat-4052	32	32	including	include	VERB
easat-4052	32	33	mesenchymal	mesenchymal	NOUN
easat-4052	32	34	cells	cell	NOUN
easat-4052	32	35	and	and	CCONJ
easat-4052	32	36	non	non	ADJ
easat-4052	32	37	-	-	ADJ
easat-4052	32	38	mesenchymal	mesenchymal	ADJ
easat-4052	32	39	cells	cell	NOUN
easat-4052	32	40	.	.	PUNCT
easat-4052	33	1	this	this	DET
easat-4052	33	2	remarkable	remarkable	ADJ
easat-4052	33	3	differentiation	differentiation	NOUN
easat-4052	33	4	capacity	capacity	NOUN
easat-4052	33	5	highlights	highlight	VERB
easat-4052	33	6	the	the	DET
easat-4052	33	7	versatility	versatility	NOUN
easat-4052	33	8	of	of	ADP
easat-4052	33	9	admscs	admscs	NOUN
easat-4052	33	10	and	and	CCONJ
easat-4052	33	11	their	their	PRON
easat-4052	33	12	potential	potential	NOUN
easat-4052	33	13	for	for	ADP
easat-4052	33	14	a	a	DET
easat-4052	33	15	wide	wide	ADJ
easat-4052	33	16	range	range	NOUN
easat-4052	33	17	of	of	ADP
easat-4052	33	18	regenerative	regenerative	ADJ
easat-4052	33	19	applications	application	NOUN
easat-4052	33	20	,	,	PUNCT
easat-4052	33	21	particularly	particularly	ADV
easat-4052	33	22	in	in	ADP
easat-4052	33	23	tissue	tissue	NOUN
easat-4052	33	24	engineering	engineering	NOUN
easat-4052	33	25	and	and	CCONJ
easat-4052	33	26	cellular	cellular	ADJ
easat-4052	33	27	therapies	therapy	NOUN
easat-4052	33	28	for	for	ADP
easat-4052	33	29	repairing	repair	VERB
easat-4052	33	30	damaged	damaged	ADJ
easat-4052	33	31	tissues	tissue	NOUN
easat-4052	33	32	,	,	PUNCT
easat-4052	33	33	including	include	VERB
easat-4052	33	34	cartilage	cartilage	NOUN
easat-4052	33	35	[	[	X
easat-4052	33	36	11	11	NUM
easat-4052	33	37	]	]	PUNCT
easat-4052	33	38	.	.	PUNCT
easat-4052	34	1	admscs	admscs	PROPN
easat-4052	34	2	,	,	PUNCT
easat-4052	34	3	with	with	ADP
easat-4052	34	4	their	their	PRON
easat-4052	34	5	ability	ability	NOUN
easat-4052	34	6	to	to	PART
easat-4052	34	7	differentiate	differentiate	VERB
easat-4052	34	8	into	into	ADP
easat-4052	34	9	chondrocytes	chondrocyte	NOUN
easat-4052	34	10	and	and	CCONJ
easat-4052	34	11	secrete	secrete	NOUN
easat-4052	34	12	ecm	ecm	NOUN
easat-4052	34	13	components	component	NOUN
easat-4052	34	14	,	,	PUNCT
easat-4052	34	15	present	present	VERB
easat-4052	34	16	a	a	DET
easat-4052	34	17	promising	promising	ADJ
easat-4052	34	18	alternative	alternative	NOUN
easat-4052	34	19	for	for	ADP
easat-4052	34	20	cartilage	cartilage	NOUN
easat-4052	34	21	regeneration	regeneration	NOUN
easat-4052	34	22	[	[	X
easat-4052	34	23	11,12	11,12	NOUN
easat-4052	34	24	]	]	PUNCT
easat-4052	34	25	.	.	PUNCT
easat-4052	35	1	combined	combine	VERB
easat-4052	35	2	with	with	ADP
easat-4052	35	3	scaffolds	scaffold	NOUN
easat-4052	35	4	,	,	PUNCT
easat-4052	35	5	these	these	DET
easat-4052	35	6	stem	stem	NOUN
easat-4052	35	7	cells	cell	NOUN
easat-4052	35	8	can	can	AUX
easat-4052	35	9	provide	provide	VERB
easat-4052	35	10	structural	structural	ADJ
easat-4052	35	11	support	support	NOUN
easat-4052	35	12	,	,	PUNCT
easat-4052	35	13	promote	promote	VERB
easat-4052	35	14	cell	cell	NOUN
easat-4052	35	15	proliferation	proliferation	NOUN
easat-4052	35	16	,	,	PUNCT
easat-4052	35	17	and	and	CCONJ
easat-4052	35	18	enhance	enhance	VERB
easat-4052	35	19	tissue	tissue	NOUN
easat-4052	35	20	formation	formation	NOUN
easat-4052	35	21	at	at	ADP
easat-4052	35	22	the	the	DET
easat-4052	35	23	defect	defect	NOUN
easat-4052	35	24	site	site	NOUN
easat-4052	35	25	.	.	PUNCT
easat-4052	36	1	furthermore	furthermore	ADV
easat-4052	36	2	,	,	PUNCT
easat-4052	36	3	admscs	admsc	NOUN
easat-4052	36	4	are	be	AUX
easat-4052	36	5	relatively	relatively	ADV
easat-4052	36	6	easy	easy	ADJ
easat-4052	36	7	to	to	PART
easat-4052	36	8	isolate	isolate	VERB
easat-4052	36	9	from	from	ADP
easat-4052	36	10	adipose	adipose	ADJ
easat-4052	36	11	tissue	tissue	NOUN
easat-4052	36	12	,	,	PUNCT
easat-4052	36	13	a	a	DET
easat-4052	36	14	readily	readily	ADV
easat-4052	36	15	accessible	accessible	ADJ
easat-4052	36	16	and	and	CCONJ
easat-4052	36	17	abundant	abundant	ADJ
easat-4052	36	18	source	source	NOUN
easat-4052	36	19	,	,	PUNCT
easat-4052	36	20	making	make	VERB
easat-4052	36	21	them	they	PRON
easat-4052	36	22	a	a	DET
easat-4052	36	23	feasible	feasible	ADJ
easat-4052	36	24	option	option	NOUN
easat-4052	36	25	for	for	ADP
easat-4052	36	26	personalized	personalized	ADJ
easat-4052	36	27	treatments	treatment	NOUN
easat-4052	36	28	.	.	PUNCT
easat-4052	37	1	incorporating	incorporate	VERB
easat-4052	37	2	scaffolds	scaffold	NOUN
easat-4052	37	3	in	in	ADP
easat-4052	37	4	tissue	tissue	NOUN
easat-4052	37	5	engineering	engineering	NOUN
easat-4052	37	6	strategies	strategy	NOUN
easat-4052	37	7	is	be	AUX
easat-4052	37	8	essential	essential	ADJ
easat-4052	37	9	to	to	PART
easat-4052	37	10	create	create	VERB
easat-4052	37	11	a	a	DET
easat-4052	37	12	suitable	suitable	ADJ
easat-4052	37	13	environment	environment	NOUN
easat-4052	37	14	for	for	ADP
easat-4052	37	15	cell	cell	NOUN
easat-4052	37	16	attachment	attachment	NOUN
easat-4052	37	17	,	,	PUNCT
easat-4052	37	18	migration	migration	NOUN
easat-4052	37	19	,	,	PUNCT
easat-4052	37	20	and	and	CCONJ
easat-4052	37	21	matrix	matrix	NOUN
easat-4052	37	22	deposition	deposition	NOUN
easat-4052	37	23	[	[	X
easat-4052	37	24	11–13	11–13	NUM
easat-4052	37	25	]	]	X
easat-4052	37	26	.	.	PUNCT
easat-4052	38	1	therefore	therefore	ADV
easat-4052	38	2	,	,	PUNCT
easat-4052	38	3	investigating	investigate	VERB
easat-4052	38	4	the	the	DET
easat-4052	38	5	use	use	NOUN
easat-4052	38	6	of	of	ADP
easat-4052	38	7	admsc	admsc	NOUN
easat-4052	38	8	-	-	PUNCT
easat-4052	38	9	loaded	load	VERB
easat-4052	38	10	scaffolds	scaffold	NOUN
easat-4052	38	11	for	for	ADP
easat-4052	38	12	knee	knee	NOUN
easat-4052	38	13	joint	joint	ADJ
easat-4052	38	14	cartilage	cartilage	NOUN
easat-4052	38	15	defects	defect	NOUN
easat-4052	38	16	is	be	AUX
easat-4052	38	17	crucial	crucial	ADJ
easat-4052	38	18	to	to	ADP
easat-4052	38	19	developing	develop	VERB
easat-4052	38	20	more	more	ADV
easat-4052	38	21	effective	effective	ADJ
easat-4052	38	22	,	,	PUNCT
easat-4052	38	23	sustainable	sustainable	ADJ
easat-4052	38	24	,	,	PUNCT
easat-4052	38	25	and	and	CCONJ
easat-4052	38	26	minimally	minimally	ADV
easat-4052	38	27	invasive	invasive	ADJ
easat-4052	38	28	therapies	therapy	NOUN
easat-4052	38	29	for	for	ADP
easat-4052	38	30	cartilage	cartilage	NOUN
easat-4052	38	31	repair	repair	NOUN
easat-4052	38	32	,	,	PUNCT
easat-4052	38	33	with	with	ADP
easat-4052	38	34	the	the	DET
easat-4052	38	35	potential	potential	NOUN
easat-4052	38	36	to	to	PART
easat-4052	38	37	significantly	significantly	ADV
easat-4052	38	38	improve	improve	VERB
easat-4052	38	39	clinical	clinical	ADJ
easat-4052	38	40	outcomes	outcome	NOUN
easat-4052	38	41	in	in	ADP
easat-4052	38	42	patients	patient	NOUN
easat-4052	38	43	suffering	suffer	VERB
easat-4052	38	44	from	from	ADP
easat-4052	38	45	cartilage	cartilage	NOUN
easat-4052	38	46	-	-	PUNCT
easat-4052	38	47	related	relate	VERB
easat-4052	38	48	disorders	disorder	NOUN
easat-4052	38	49	[	[	X
easat-4052	38	50	11,12	11,12	NOUN
easat-4052	38	51	]	]	PUNCT
easat-4052	38	52	.	.	PUNCT
easat-4052	39	1	this	this	DET
easat-4052	39	2	literature	literature	NOUN
easat-4052	39	3	review	review	NOUN
easat-4052	39	4	evaluates	evaluate	VERB
easat-4052	39	5	the	the	DET
easat-4052	39	6	current	current	ADJ
easat-4052	39	7	progress	progress	NOUN
easat-4052	39	8	and	and	CCONJ
easat-4052	39	9	challenges	challenge	NOUN
easat-4052	39	10	in	in	ADP
easat-4052	39	11	combining	combine	VERB
easat-4052	39	12	scaffolds	scaffold	NOUN
easat-4052	39	13	with	with	ADP
easat-4052	39	14	admscs	admscs	NOUN
easat-4052	39	15	for	for	ADP
easat-4052	39	16	knee	knee	NOUN
easat-4052	39	17	cartilage	cartilage	NOUN
easat-4052	39	18	regeneration	regeneration	NOUN
easat-4052	39	19	.	.	PUNCT
easat-4052	40	1	2	2	X
easat-4052	40	2	.	.	X
easat-4052	40	3	methodology	methodology	NOUN
easat-4052	40	4	this	this	DET
easat-4052	40	5	study	study	NOUN
easat-4052	40	6	was	be	AUX
easat-4052	40	7	conducted	conduct	VERB
easat-4052	40	8	following	follow	VERB
easat-4052	40	9	a	a	DET
easat-4052	40	10	comprehensive	comprehensive	ADJ
easat-4052	40	11	review	review	NOUN
easat-4052	40	12	of	of	ADP
easat-4052	40	13	relevant	relevant	ADJ
easat-4052	40	14	literature	literature	NOUN
easat-4052	40	15	.	.	PUNCT
easat-4052	41	1	data	datum	NOUN
easat-4052	41	2	were	be	AUX
easat-4052	41	3	gathered	gather	VERB
easat-4052	41	4	through	through	ADP
easat-4052	41	5	electronic	electronic	ADJ
easat-4052	41	6	databases	database	NOUN
easat-4052	41	7	such	such	ADJ
easat-4052	41	8	as	as	ADP
easat-4052	41	9	pubmed	pubmed	PROPN
easat-4052	41	10	,	,	PUNCT
easat-4052	41	11	sciencedirect	sciencedirect	PROPN
easat-4052	41	12	,	,	PUNCT
easat-4052	41	13	and	and	CCONJ
easat-4052	41	14	google	google	PROPN
easat-4052	41	15	scholar	scholar	NOUN
easat-4052	41	16	,	,	PUNCT
easat-4052	41	17	focusing	focus	VERB
easat-4052	41	18	on	on	ADP
easat-4052	41	19	articles	article	NOUN
easat-4052	41	20	published	publish	VERB
easat-4052	41	21	within	within	ADP
easat-4052	41	22	the	the	DET
easat-4052	41	23	last	last	ADJ
easat-4052	41	24	ten	ten	NUM
easat-4052	41	25	years	year	NOUN
easat-4052	41	26	.	.	PUNCT
easat-4052	42	1	the	the	DET
easat-4052	42	2	search	search	NOUN
easat-4052	42	3	utilized	utilize	VERB
easat-4052	42	4	key	key	ADJ
easat-4052	42	5	terms	term	NOUN
easat-4052	42	6	including	include	VERB
easat-4052	42	7	"	"	PUNCT
easat-4052	42	8	adipose	adipose	NOUN
easat-4052	42	9	-	-	PUNCT
easat-4052	42	10	derived	derive	VERB
easat-4052	42	11	mesenchymal	mesenchymal	NOUN
easat-4052	42	12	stem	stem	NOUN
easat-4052	42	13	cells	cell	NOUN
easat-4052	42	14	"	"	PUNCT
easat-4052	42	15	,	,	PUNCT
easat-4052	42	16	"	"	PUNCT
easat-4052	42	17	knee	knee	NOUN
easat-4052	42	18	joint	joint	ADJ
easat-4052	42	19	cartilage	cartilage	NOUN
easat-4052	42	20	defects	defect	NOUN
easat-4052	42	21	"	"	PUNCT
easat-4052	42	22	,	,	PUNCT
easat-4052	42	23	and	and	CCONJ
easat-4052	42	24	"	"	PUNCT
easat-4052	42	25	tissue	tissue	NOUN
easat-4052	42	26	scaffold	scaffold	NOUN
easat-4052	42	27	"	"	PUNCT
easat-4052	42	28	.	.	PUNCT
easat-4052	43	1	only	only	ADV
easat-4052	43	2	english	english	ADJ
easat-4052	43	3	-	-	PUNCT
easat-4052	43	4	language	language	NOUN
easat-4052	43	5	studies	study	NOUN
easat-4052	43	6	focusing	focus	VERB
easat-4052	43	7	on	on	ADP
easat-4052	43	8	the	the	DET
easat-4052	43	9	application	application	NOUN
easat-4052	43	10	of	of	ADP
easat-4052	43	11	admsc	admsc	NOUN
easat-4052	43	12	-	-	PUNCT
easat-4052	43	13	loaded	load	VERB
easat-4052	43	14	scaffolds	scaffold	NOUN
easat-4052	43	15	for	for	ADP
easat-4052	43	16	knee	knee	NOUN
easat-4052	43	17	joint	joint	ADJ
easat-4052	43	18	cartilage	cartilage	NOUN
easat-4052	43	19	defects	defect	NOUN
easat-4052	43	20	were	be	AUX
easat-4052	43	21	included	include	VERB
easat-4052	43	22	in	in	ADP
easat-4052	43	23	the	the	DET
easat-4052	43	24	analysis	analysis	NOUN
easat-4052	43	25	.	.	PUNCT
easat-4052	44	1	3	3	X
easat-4052	44	2	.	.	X
easat-4052	44	3	results	result	VERB
easat-4052	44	4	3.1	3.1	NUM
easat-4052	44	5	.	.	PUNCT
easat-4052	44	6	scaffold	scaffold	NOUN
easat-4052	44	7	-	-	PUNCT
easat-4052	44	8	admsc	admsc	NOUN
easat-4052	44	9	synergy	synergy	NOUN
easat-4052	44	10	in	in	ADP
easat-4052	44	11	knee	knee	NOUN
easat-4052	44	12	cartilage	cartilage	NOUN
easat-4052	44	13	repair	repair	VERB
easat-4052	44	14	the	the	DET
easat-4052	44	15	dynamic	dynamic	ADJ
easat-4052	44	16	interaction	interaction	NOUN
easat-4052	44	17	between	between	ADP
easat-4052	44	18	admscs	admsc	NOUN
easat-4052	44	19	and	and	CCONJ
easat-4052	44	20	scaffolds	scaffold	NOUN
easat-4052	44	21	is	be	AUX
easat-4052	44	22	a	a	DET
easat-4052	44	23	cornerstone	cornerstone	NOUN
easat-4052	44	24	of	of	ADP
easat-4052	44	25	effective	effective	ADJ
easat-4052	44	26	cartilage	cartilage	NOUN
easat-4052	44	27	repair	repair	NOUN
easat-4052	44	28	strategies	strategy	NOUN
easat-4052	44	29	.	.	PUNCT
easat-4052	45	1	upon	upon	SCONJ
easat-4052	45	2	scaffold	scaffold	NOUN
easat-4052	45	3	seeding	seeding	NOUN
easat-4052	45	4	,	,	PUNCT
easat-4052	45	5	admscs	admsc	NOUN
easat-4052	45	6	adhere	adhere	VERB
easat-4052	45	7	to	to	ADP
easat-4052	45	8	the	the	DET
easat-4052	45	9	scaffold	scaffold	NOUN
easat-4052	45	10	surface	surface	NOUN
easat-4052	45	11	via	via	ADP
easat-4052	45	12	integrin	integrin	NOUN
easat-4052	45	13	-	-	PUNCT
easat-4052	45	14	mediated	mediate	VERB
easat-4052	45	15	binding	binding	NOUN
easat-4052	45	16	,	,	PUNCT
easat-4052	45	17	which	which	PRON
easat-4052	45	18	triggers	trigger	VERB
easat-4052	45	19	intracellular	intracellular	ADJ
easat-4052	45	20	signaling	signal	VERB
easat-4052	45	21	cascades	cascade	NOUN
easat-4052	45	22	essential	essential	ADJ
easat-4052	45	23	for	for	ADP
easat-4052	45	24	cell	cell	NOUN
easat-4052	45	25	survival	survival	NOUN
easat-4052	45	26	,	,	PUNCT
easat-4052	45	27	proliferation	proliferation	NOUN
easat-4052	45	28	,	,	PUNCT
easat-4052	45	29	and	and	CCONJ
easat-4052	45	30	differentiation	differentiation	NOUN
easat-4052	45	31	.	.	PUNCT
easat-4052	46	1	the	the	DET
easat-4052	46	2	success	success	NOUN
easat-4052	46	3	of	of	ADP
easat-4052	46	4	these	these	DET
easat-4052	46	5	interactions	interaction	NOUN
easat-4052	46	6	is	be	AUX
easat-4052	46	7	strongly	strongly	ADV
easat-4052	46	8	influenced	influence	VERB
easat-4052	46	9	by	by	ADP
easat-4052	46	10	the	the	DET
easat-4052	46	11	scaffold	scaffold	NOUN
easat-4052	46	12	’s	’s	PART
easat-4052	46	13	biophysical	biophysical	ADJ
easat-4052	46	14	and	and	CCONJ
easat-4052	46	15	biochemical	biochemical	ADJ
easat-4052	46	16	properties	property	NOUN
easat-4052	46	17	,	,	PUNCT
easat-4052	46	18	including	include	VERB
easat-4052	46	19	porosity	porosity	NOUN
easat-4052	46	20	,	,	PUNCT
easat-4052	46	21	mechanical	mechanical	ADJ
easat-4052	46	22	stiffness	stiffness	NOUN
easat-4052	46	23	,	,	PUNCT
easat-4052	46	24	and	and	CCONJ
easat-4052	46	25	surface	surface	NOUN
easat-4052	46	26	functionalization	functionalization	NOUN
easat-4052	46	27	.	.	PUNCT
easat-4052	47	1	scaffolds	scaffold	NOUN
easat-4052	47	2	designed	design	VERB
easat-4052	47	3	with	with	ADP
easat-4052	47	4	optimized	optimize	VERB
easat-4052	47	5	properties	property	NOUN
easat-4052	47	6	provide	provide	VERB
easat-4052	47	7	mechanical	mechanical	ADJ
easat-4052	47	8	and	and	CCONJ
easat-4052	47	9	biochemical	biochemical	ADJ
easat-4052	47	10	cues	cue	NOUN
easat-4052	47	11	that	that	PRON
easat-4052	47	12	replicate	replicate	VERB
easat-4052	47	13	the	the	DET
easat-4052	47	14	natural	natural	ADJ
easat-4052	47	15	cartilage	cartilage	NOUN
easat-4052	47	16	ecm	ecm	NOUN
easat-4052	47	17	,	,	PUNCT
easat-4052	47	18	thereby	thereby	ADV
easat-4052	47	19	promoting	promote	VERB
easat-4052	47	20	the	the	DET
easat-4052	47	21	chondrogenic	chondrogenic	ADJ
easat-4052	47	22	differentiation	differentiation	NOUN
easat-4052	47	23	of	of	ADP
easat-4052	47	24	admscs	admscs	NOUN
easat-4052	47	25	.	.	PUNCT
easat-4052	48	1	moreover	moreover	ADV
easat-4052	48	2	,	,	PUNCT
easat-4052	48	3	scaffolds	scaffold	NOUN
easat-4052	48	4	can	can	AUX
easat-4052	48	5	be	be	AUX
easat-4052	48	6	engineered	engineer	VERB
easat-4052	48	7	to	to	PART
easat-4052	48	8	incorporate	incorporate	VERB
easat-4052	48	9	bioactive	bioactive	ADJ
easat-4052	48	10	molecules	molecule	NOUN
easat-4052	48	11	,	,	PUNCT
easat-4052	48	12	such	such	ADJ
easat-4052	48	13	as	as	ADP
easat-4052	48	14	transforming	transform	VERB
easat-4052	48	15	growth	growth	NOUN
easat-4052	48	16	factor	factor	NOUN
easat-4052	48	17	-	-	PUNCT
easat-4052	48	18	β	β	X
easat-4052	48	19	(	(	PUNCT
easat-4052	48	20	tgf	tgf	PROPN
easat-4052	48	21	-	-	PUNCT
easat-4052	48	22	β	β	NOUN
easat-4052	48	23	)	)	PUNCT
easat-4052	48	24	and	and	CCONJ
easat-4052	48	25	bone	bone	NOUN
easat-4052	48	26	morphogenetic	morphogenetic	ADJ
easat-4052	48	27	protein-2	protein-2	PROPN
easat-4052	48	28	(	(	PUNCT
easat-4052	48	29	bmp-2	bmp-2	NOUN
easat-4052	48	30	)	)	PUNCT
easat-4052	48	31	,	,	PUNCT
easat-4052	48	32	to	to	PART
easat-4052	48	33	further	far	ADV
easat-4052	48	34	augment	augment	VERB
easat-4052	48	35	cellular	cellular	ADJ
easat-4052	48	36	activity	activity	NOUN
easat-4052	48	37	and	and	CCONJ
easat-4052	48	38	steer	steer	VERB
easat-4052	48	39	lineagespecific	lineagespecific	ADJ
easat-4052	48	40	differentiation	differentiation	NOUN
easat-4052	48	41	pathways	pathway	NOUN
easat-4052	49	1	[	[	X
easat-4052	49	2	14	14	NUM
easat-4052	49	3	]	]	PUNCT
easat-4052	49	4	.	.	PUNCT
easat-4052	50	1	effective	effective	ADJ
easat-4052	50	2	tissue	tissue	NOUN
easat-4052	50	3	integration	integration	NOUN
easat-4052	50	4	is	be	AUX
easat-4052	50	5	paramount	paramount	ADJ
easat-4052	50	6	for	for	ADP
easat-4052	50	7	the	the	DET
easat-4052	50	8	long	long	ADJ
easat-4052	50	9	-	-	PUNCT
easat-4052	50	10	term	term	NOUN
easat-4052	50	11	success	success	NOUN
easat-4052	50	12	of	of	ADP
easat-4052	50	13	scaffold	scaffold	NOUN
easat-4052	50	14	-	-	PUNCT
easat-4052	50	15	based	base	VERB
easat-4052	50	16	cartilage	cartilage	NOUN
easat-4052	50	17	repair	repair	NOUN
easat-4052	50	18	.	.	PUNCT
easat-4052	51	1	seamless	seamless	ADJ
easat-4052	51	2	integration	integration	NOUN
easat-4052	51	3	between	between	ADP
easat-4052	51	4	the	the	DET
easat-4052	51	5	scaffold	scaffold	NOUN
easat-4052	51	6	and	and	CCONJ
easat-4052	51	7	surrounding	surround	VERB
easat-4052	51	8	native	native	ADJ
easat-4052	51	9	tissue	tissue	NOUN
easat-4052	51	10	is	be	AUX
easat-4052	51	11	essential	essential	ADJ
easat-4052	51	12	to	to	PART
easat-4052	51	13	establish	establish	VERB
easat-4052	51	14	a	a	DET
easat-4052	51	15	stable	stable	ADJ
easat-4052	51	16	9594	9594	NUM
easat-4052	51	17	edelweiss	edelweiss	PROPN
easat-4052	51	18	applied	apply	VERB
easat-4052	51	19	science	science	NOUN
easat-4052	51	20	and	and	CCONJ
easat-4052	51	21	technology	technology	NOUN
easat-4052	51	22	issn	issn	PROPN
easat-4052	51	23	:	:	PUNCT
easat-4052	51	24	2576	2576	NUM
easat-4052	51	25	-	-	SYM
easat-4052	51	26	8484	8484	NUM
easat-4052	51	27	vol	vol	NOUN
easat-4052	51	28	.	.	PROPN
easat-4052	51	29	8	8	NUM
easat-4052	51	30	,	,	PUNCT
easat-4052	51	31	no	no	INTJ
easat-4052	51	32	.	.	NOUN
easat-4052	52	1	6	6	NUM
easat-4052	52	2	:	:	SYM
easat-4052	52	3	9592	9592	NUM
easat-4052	52	4	-	-	SYM
easat-4052	52	5	9604	9604	NUM
easat-4052	52	6	,	,	PUNCT
easat-4052	52	7	2024	2024	NUM
easat-4052	52	8	doi	doi	NOUN
easat-4052	52	9	:	:	PUNCT
easat-4052	52	10	10.55214/25768484.v8i6.4052	10.55214/25768484.v8i6.4052	NUM
easat-4052	53	1	©	©	ADP
easat-4052	53	2	2024	2024	NUM
easat-4052	53	3	by	by	ADP
easat-4052	53	4	the	the	DET
easat-4052	53	5	authors	author	NOUN
easat-4052	53	6	;	;	PUNCT
easat-4052	53	7	licensee	licensee	PROPN
easat-4052	53	8	learning	learning	PROPN
easat-4052	53	9	gate	gate	PROPN
easat-4052	53	10	interface	interface	NOUN
easat-4052	53	11	capable	capable	ADJ
easat-4052	53	12	of	of	ADP
easat-4052	53	13	withstanding	withstand	VERB
easat-4052	53	14	load	load	NOUN
easat-4052	53	15	-	-	PUNCT
easat-4052	53	16	bearing	bear	VERB
easat-4052	53	17	activities	activity	NOUN
easat-4052	53	18	.	.	PUNCT
easat-4052	54	1	admscs	admscs	PROPN
easat-4052	54	2	play	play	VERB
easat-4052	54	3	a	a	DET
easat-4052	54	4	pivotal	pivotal	ADJ
easat-4052	54	5	role	role	NOUN
easat-4052	54	6	in	in	ADP
easat-4052	54	7	this	this	DET
easat-4052	54	8	process	process	NOUN
easat-4052	54	9	by	by	ADP
easat-4052	54	10	secreting	secrete	VERB
easat-4052	54	11	matrix	matrix	NOUN
easat-4052	54	12	metalloproteinases	metalloproteinase	NOUN
easat-4052	54	13	(	(	PUNCT
easat-4052	54	14	mmps	mmp	NOUN
easat-4052	54	15	)	)	PUNCT
easat-4052	54	16	and	and	CCONJ
easat-4052	54	17	other	other	ADJ
easat-4052	54	18	remodeling	remodeling	NOUN
easat-4052	54	19	enzymes	enzyme	NOUN
easat-4052	54	20	,	,	PUNCT
easat-4052	54	21	which	which	PRON
easat-4052	54	22	facilitate	facilitate	VERB
easat-4052	54	23	the	the	DET
easat-4052	54	24	degradation	degradation	NOUN
easat-4052	54	25	of	of	ADP
easat-4052	54	26	damaged	damage	VERB
easat-4052	54	27	cartilage	cartilage	NOUN
easat-4052	54	28	and	and	CCONJ
easat-4052	54	29	the	the	DET
easat-4052	54	30	deposition	deposition	NOUN
easat-4052	54	31	of	of	ADP
easat-4052	54	32	newly	newly	ADV
easat-4052	54	33	synthesized	synthesize	VERB
easat-4052	54	34	matrix	matrix	NOUN
easat-4052	54	35	components	component	NOUN
easat-4052	54	36	.	.	PUNCT
easat-4052	55	1	concurrently	concurrently	ADV
easat-4052	55	2	,	,	PUNCT
easat-4052	55	3	admscs	admsc	NOUN
easat-4052	55	4	produce	produce	VERB
easat-4052	55	5	pro	pro	ADJ
easat-4052	55	6	-	-	ADJ
easat-4052	55	7	angiogenic	angiogenic	ADJ
easat-4052	55	8	factors	factor	NOUN
easat-4052	55	9	,	,	PUNCT
easat-4052	55	10	such	such	ADJ
easat-4052	55	11	as	as	ADP
easat-4052	55	12	vascular	vascular	ADJ
easat-4052	55	13	endothelial	endothelial	ADJ
easat-4052	55	14	growth	growth	NOUN
easat-4052	55	15	factor	factor	NOUN
easat-4052	55	16	(	(	PUNCT
easat-4052	55	17	vegf	vegf	PROPN
easat-4052	55	18	)	)	PUNCT
easat-4052	55	19	,	,	PUNCT
easat-4052	55	20	that	that	PRON
easat-4052	55	21	drive	drive	VERB
easat-4052	55	22	neovascularization	neovascularization	NOUN
easat-4052	55	23	within	within	ADP
easat-4052	55	24	the	the	DET
easat-4052	55	25	adjacent	adjacent	ADJ
easat-4052	55	26	subchondral	subchondral	ADJ
easat-4052	55	27	bone	bone	NOUN
easat-4052	55	28	.	.	PUNCT
easat-4052	56	1	this	this	DET
easat-4052	56	2	vascularization	vascularization	NOUN
easat-4052	56	3	enhances	enhance	VERB
easat-4052	56	4	nutrient	nutrient	NOUN
easat-4052	56	5	and	and	CCONJ
easat-4052	56	6	oxygen	oxygen	NOUN
easat-4052	56	7	delivery	delivery	NOUN
easat-4052	56	8	,	,	PUNCT
easat-4052	56	9	supporting	support	VERB
easat-4052	56	10	cellular	cellular	ADJ
easat-4052	56	11	activity	activity	NOUN
easat-4052	56	12	and	and	CCONJ
easat-4052	56	13	tissue	tissue	NOUN
easat-4052	56	14	maturation	maturation	NOUN
easat-4052	56	15	.	.	PUNCT
easat-4052	57	1	advanced	advanced	ADJ
easat-4052	57	2	scaffold	scaffold	NOUN
easat-4052	57	3	designs	design	NOUN
easat-4052	57	4	featuring	feature	VERB
easat-4052	57	5	gradient	gradient	ADJ
easat-4052	57	6	architectures	architecture	NOUN
easat-4052	57	7	or	or	CCONJ
easat-4052	57	8	hierarchical	hierarchical	ADJ
easat-4052	57	9	structures	structure	NOUN
easat-4052	57	10	further	far	ADV
easat-4052	57	11	promote	promote	VERB
easat-4052	57	12	effective	effective	ADJ
easat-4052	57	13	integration	integration	NOUN
easat-4052	57	14	by	by	ADP
easat-4052	57	15	replicating	replicate	VERB
easat-4052	57	16	the	the	DET
easat-4052	57	17	natural	natural	ADJ
easat-4052	57	18	transition	transition	NOUN
easat-4052	57	19	between	between	ADP
easat-4052	57	20	cartilage	cartilage	NOUN
easat-4052	57	21	and	and	CCONJ
easat-4052	57	22	subchondral	subchondral	ADJ
easat-4052	57	23	bone	bone	NOUN
easat-4052	57	24	,	,	PUNCT
easat-4052	57	25	thereby	thereby	ADV
easat-4052	57	26	optimizing	optimize	VERB
easat-4052	57	27	biomechanical	biomechanical	ADJ
easat-4052	57	28	and	and	CCONJ
easat-4052	57	29	biological	biological	ADJ
easat-4052	57	30	compatibility	compatibility	NOUN
easat-4052	57	31	[	[	X
easat-4052	57	32	15	15	NUM
easat-4052	57	33	]	]	PUNCT
easat-4052	57	34	.	.	PUNCT
easat-4052	58	1	the	the	DET
easat-4052	58	2	primary	primary	ADJ
easat-4052	58	3	objective	objective	NOUN
easat-4052	58	4	of	of	ADP
easat-4052	58	5	scaffold	scaffold	NOUN
easat-4052	58	6	-	-	PUNCT
easat-4052	58	7	admsc	admsc	NOUN
easat-4052	58	8	synergy	synergy	NOUN
easat-4052	58	9	is	be	AUX
easat-4052	58	10	the	the	DET
easat-4052	58	11	regeneration	regeneration	NOUN
easat-4052	58	12	of	of	ADP
easat-4052	58	13	hyaline	hyaline	NOUN
easat-4052	58	14	-	-	PUNCT
easat-4052	58	15	like	like	ADJ
easat-4052	58	16	cartilage	cartilage	NOUN
easat-4052	58	17	that	that	PRON
easat-4052	58	18	closely	closely	ADV
easat-4052	58	19	mirrors	mirror	VERB
easat-4052	58	20	native	native	ADJ
easat-4052	58	21	tissue	tissue	NOUN
easat-4052	58	22	in	in	ADP
easat-4052	58	23	both	both	CCONJ
easat-4052	58	24	structural	structural	ADJ
easat-4052	58	25	and	and	CCONJ
easat-4052	58	26	functional	functional	ADJ
easat-4052	58	27	properties	property	NOUN
easat-4052	58	28	.	.	PUNCT
easat-4052	59	1	under	under	ADP
easat-4052	59	2	optimal	optimal	ADJ
easat-4052	59	3	mechanical	mechanical	ADJ
easat-4052	59	4	and	and	CCONJ
easat-4052	59	5	biochemical	biochemical	ADJ
easat-4052	59	6	cues	cue	NOUN
easat-4052	59	7	,	,	PUNCT
easat-4052	59	8	admscs	admsc	NOUN
easat-4052	59	9	differentiate	differentiate	VERB
easat-4052	59	10	into	into	ADP
easat-4052	59	11	chondrocytes	chondrocyte	NOUN
easat-4052	59	12	,	,	PUNCT
easat-4052	59	13	synthesizing	synthesize	VERB
easat-4052	59	14	critical	critical	ADJ
easat-4052	59	15	cartilage	cartilage	NOUN
easat-4052	59	16	-	-	PUNCT
easat-4052	59	17	specific	specific	ADJ
easat-4052	59	18	matrix	matrix	NOUN
easat-4052	59	19	components	component	NOUN
easat-4052	59	20	such	such	ADJ
easat-4052	59	21	as	as	ADP
easat-4052	59	22	type	type	NOUN
easat-4052	59	23	ii	ii	PROPN
easat-4052	59	24	collagen	collagen	NOUN
easat-4052	59	25	and	and	CCONJ
easat-4052	59	26	proteoglycans	proteoglycan	NOUN
easat-4052	59	27	.	.	PUNCT
easat-4052	60	1	scaffolds	scaffold	NOUN
easat-4052	60	2	serve	serve	VERB
easat-4052	60	3	not	not	PART
easat-4052	60	4	only	only	ADV
easat-4052	60	5	as	as	ADP
easat-4052	60	6	a	a	DET
easat-4052	60	7	structural	structural	ADJ
easat-4052	60	8	framework	framework	NOUN
easat-4052	60	9	but	but	CCONJ
easat-4052	60	10	also	also	ADV
easat-4052	60	11	as	as	ADP
easat-4052	60	12	a	a	DET
easat-4052	60	13	template	template	NOUN
easat-4052	60	14	for	for	ADP
easat-4052	60	15	organized	organized	ADJ
easat-4052	60	16	ecm	ecm	NOUN
easat-4052	60	17	deposition	deposition	NOUN
easat-4052	60	18	.	.	PUNCT
easat-4052	61	1	biodegradable	biodegradable	ADJ
easat-4052	61	2	scaffolds	scaffold	NOUN
easat-4052	61	3	gradually	gradually	ADV
easat-4052	61	4	break	break	VERB
easat-4052	61	5	down	down	ADP
easat-4052	61	6	in	in	ADP
easat-4052	61	7	response	response	NOUN
easat-4052	61	8	to	to	ADP
easat-4052	61	9	enzymatic	enzymatic	ADJ
easat-4052	61	10	activity	activity	NOUN
easat-4052	61	11	,	,	PUNCT
easat-4052	61	12	creating	create	VERB
easat-4052	61	13	space	space	NOUN
easat-4052	61	14	for	for	ADP
easat-4052	61	15	new	new	ADJ
easat-4052	61	16	tissue	tissue	NOUN
easat-4052	61	17	formation	formation	NOUN
easat-4052	61	18	while	while	SCONJ
easat-4052	61	19	preserving	preserve	VERB
easat-4052	61	20	mechanical	mechanical	ADJ
easat-4052	61	21	integrity	integrity	NOUN
easat-4052	61	22	throughout	throughout	ADP
easat-4052	61	23	the	the	DET
easat-4052	61	24	repair	repair	NOUN
easat-4052	61	25	process	process	NOUN
easat-4052	61	26	.	.	PUNCT
easat-4052	62	1	advanced	advanced	ADJ
easat-4052	62	2	techniques	technique	NOUN
easat-4052	62	3	,	,	PUNCT
easat-4052	62	4	such	such	ADJ
easat-4052	62	5	as	as	ADP
easat-4052	62	6	dynamic	dynamic	ADJ
easat-4052	62	7	mechanical	mechanical	ADJ
easat-4052	62	8	loading	loading	NOUN
easat-4052	62	9	in	in	ADP
easat-4052	62	10	bioreactors	bioreactor	NOUN
easat-4052	62	11	,	,	PUNCT
easat-4052	62	12	further	far	ADV
easat-4052	62	13	enhance	enhance	VERB
easat-4052	62	14	cartilage	cartilage	NOUN
easat-4052	62	15	regeneration	regeneration	NOUN
easat-4052	62	16	by	by	ADP
easat-4052	62	17	simulating	simulate	VERB
easat-4052	62	18	physiological	physiological	ADJ
easat-4052	62	19	conditions	condition	NOUN
easat-4052	62	20	and	and	CCONJ
easat-4052	62	21	promoting	promote	VERB
easat-4052	62	22	the	the	DET
easat-4052	62	23	alignment	alignment	NOUN
easat-4052	62	24	of	of	ADP
easat-4052	62	25	collagen	collagen	NOUN
easat-4052	62	26	fibers	fiber	NOUN
easat-4052	62	27	[	[	X
easat-4052	62	28	16	16	NUM
easat-4052	62	29	]	]	PUNCT
easat-4052	62	30	.	.	PUNCT
easat-4052	63	1	the	the	DET
easat-4052	63	2	interplay	interplay	NOUN
easat-4052	63	3	between	between	ADP
easat-4052	63	4	scaffolds	scaffold	NOUN
easat-4052	63	5	and	and	CCONJ
easat-4052	63	6	admscs	admsc	NOUN
easat-4052	63	7	significantly	significantly	ADV
easat-4052	63	8	enhances	enhance	VERB
easat-4052	63	9	cartilage	cartilage	NOUN
easat-4052	63	10	repair	repair	NOUN
easat-4052	63	11	by	by	ADP
easat-4052	63	12	synchronizing	synchronize	VERB
easat-4052	63	13	cellular	cellular	ADJ
easat-4052	63	14	activity	activity	NOUN
easat-4052	63	15	with	with	ADP
easat-4052	63	16	structural	structural	ADJ
easat-4052	63	17	support	support	NOUN
easat-4052	63	18	.	.	PUNCT
easat-4052	64	1	scaffolds	scaffold	NOUN
easat-4052	64	2	provide	provide	VERB
easat-4052	64	3	a	a	DET
easat-4052	64	4	protective	protective	ADJ
easat-4052	64	5	niche	niche	NOUN
easat-4052	64	6	for	for	ADP
easat-4052	64	7	admscs	admscs	NOUN
easat-4052	64	8	,	,	PUNCT
easat-4052	64	9	ensuring	ensure	VERB
easat-4052	64	10	their	their	PRON
easat-4052	64	11	localization	localization	NOUN
easat-4052	64	12	and	and	CCONJ
easat-4052	64	13	prolonged	prolonged	ADJ
easat-4052	64	14	functionality	functionality	NOUN
easat-4052	64	15	,	,	PUNCT
easat-4052	64	16	while	while	SCONJ
easat-4052	64	17	the	the	DET
easat-4052	64	18	bioactive	bioactive	ADJ
easat-4052	64	19	factors	factor	NOUN
easat-4052	64	20	secreted	secrete	VERB
easat-4052	64	21	by	by	ADP
easat-4052	64	22	admscs	admscs	NOUN
easat-4052	64	23	accelerate	accelerate	VERB
easat-4052	64	24	scaffold	scaffold	NOUN
easat-4052	64	25	remodeling	remodeling	NOUN
easat-4052	64	26	and	and	CCONJ
easat-4052	64	27	stimulate	stimulate	VERB
easat-4052	64	28	endogenous	endogenous	ADJ
easat-4052	64	29	tissue	tissue	NOUN
easat-4052	64	30	repair	repair	NOUN
easat-4052	64	31	.	.	PUNCT
easat-4052	65	1	this	this	DET
easat-4052	65	2	synergistic	synergistic	ADJ
easat-4052	65	3	interaction	interaction	NOUN
easat-4052	65	4	establishes	establish	VERB
easat-4052	65	5	a	a	DET
easat-4052	65	6	microenvironment	microenvironment	NOUN
easat-4052	65	7	optimized	optimize	VERB
easat-4052	65	8	for	for	ADP
easat-4052	65	9	the	the	DET
easat-4052	65	10	regeneration	regeneration	NOUN
easat-4052	65	11	of	of	ADP
easat-4052	65	12	durable	durable	ADJ
easat-4052	65	13	,	,	PUNCT
easat-4052	65	14	biomechanically	biomechanically	ADV
easat-4052	65	15	robust	robust	ADJ
easat-4052	65	16	cartilage	cartilage	NOUN
easat-4052	65	17	with	with	ADP
easat-4052	65	18	extended	extended	ADJ
easat-4052	65	19	functional	functional	ADJ
easat-4052	65	20	longevity	longevity	NOUN
easat-4052	65	21	[	[	X
easat-4052	65	22	14–16	14–16	NUM
easat-4052	65	23	]	]	SYM
easat-4052	65	24	.	.	PUNCT
easat-4052	66	1	3.2	3.2	NUM
easat-4052	66	2	.	.	PUNCT
easat-4052	67	1	clinical	clinical	ADJ
easat-4052	67	2	studies	study	NOUN
easat-4052	67	3	and	and	CCONJ
easat-4052	67	4	current	current	ADJ
easat-4052	67	5	applications	application	NOUN
easat-4052	67	6	the	the	DET
easat-4052	67	7	systematic	systematic	ADJ
easat-4052	67	8	review	review	NOUN
easat-4052	67	9	by	by	ADP
easat-4052	67	10	perdisa	perdisa	NOUN
easat-4052	67	11	et	et	PROPN
easat-4052	67	12	al	al	PROPN
easat-4052	67	13	.	.	PROPN
easat-4052	68	1	(	(	PUNCT
easat-4052	68	2	2015	2015	NUM
easat-4052	68	3	)	)	PUNCT
easat-4052	68	4	highlights	highlight	NOUN
easat-4052	68	5	the	the	DET
easat-4052	68	6	considerable	considerable	ADJ
easat-4052	68	7	potential	potential	NOUN
easat-4052	68	8	of	of	ADP
easat-4052	68	9	adiposederived	adiposederive	VERB
easat-4052	68	10	mesenchymal	mesenchymal	ADJ
easat-4052	68	11	stem	stem	NOUN
easat-4052	68	12	cells	cell	NOUN
easat-4052	68	13	(	(	PUNCT
easat-4052	68	14	admscs	admscs	NOUN
easat-4052	68	15	)	)	PUNCT
easat-4052	68	16	for	for	ADP
easat-4052	68	17	treating	treat	VERB
easat-4052	68	18	articular	articular	ADJ
easat-4052	68	19	cartilage	cartilage	NOUN
easat-4052	68	20	defects	defect	NOUN
easat-4052	68	21	,	,	PUNCT
easat-4052	68	22	supported	support	VERB
easat-4052	68	23	by	by	ADP
easat-4052	68	24	both	both	CCONJ
easat-4052	68	25	preclinical	preclinical	ADJ
easat-4052	68	26	and	and	CCONJ
easat-4052	68	27	clinical	clinical	ADJ
easat-4052	68	28	evidence	evidence	NOUN
easat-4052	68	29	.	.	PUNCT
easat-4052	69	1	in	in	ADP
easat-4052	69	2	animal	animal	NOUN
easat-4052	69	3	studies	study	NOUN
easat-4052	69	4	,	,	PUNCT
easat-4052	69	5	admscs	admsc	NOUN
easat-4052	69	6	showed	show	VERB
easat-4052	69	7	effective	effective	ADJ
easat-4052	69	8	chondrogenic	chondrogenic	ADJ
easat-4052	69	9	differentiation	differentiation	NOUN
easat-4052	69	10	,	,	PUNCT
easat-4052	69	11	cartilage	cartilage	NOUN
easat-4052	69	12	repair	repair	NOUN
easat-4052	69	13	,	,	PUNCT
easat-4052	69	14	and	and	CCONJ
easat-4052	69	15	integration	integration	NOUN
easat-4052	69	16	with	with	ADP
easat-4052	69	17	surrounding	surround	VERB
easat-4052	69	18	tissues	tissue	NOUN
easat-4052	69	19	,	,	PUNCT
easat-4052	69	20	especially	especially	ADV
easat-4052	69	21	when	when	SCONJ
easat-4052	69	22	combined	combine	VERB
easat-4052	69	23	with	with	ADP
easat-4052	69	24	suitable	suitable	ADJ
easat-4052	69	25	scaffolds	scaffold	NOUN
easat-4052	69	26	or	or	CCONJ
easat-4052	69	27	used	use	VERB
easat-4052	69	28	in	in	ADP
easat-4052	69	29	cell	cell	NOUN
easat-4052	69	30	-	-	PUNCT
easat-4052	69	31	based	base	VERB
easat-4052	69	32	therapies	therapy	NOUN
easat-4052	69	33	.	.	PUNCT
easat-4052	70	1	clinical	clinical	ADJ
easat-4052	70	2	trials	trial	NOUN
easat-4052	70	3	reinforced	reinforce	VERB
easat-4052	70	4	these	these	DET
easat-4052	70	5	findings	finding	NOUN
easat-4052	70	6	,	,	PUNCT
easat-4052	70	7	demonstrating	demonstrate	VERB
easat-4052	70	8	notable	notable	ADJ
easat-4052	70	9	improvements	improvement	NOUN
easat-4052	70	10	in	in	ADP
easat-4052	70	11	cartilage	cartilage	NOUN
easat-4052	70	12	repair	repair	NOUN
easat-4052	70	13	,	,	PUNCT
easat-4052	70	14	pain	pain	NOUN
easat-4052	70	15	reduction	reduction	NOUN
easat-4052	70	16	,	,	PUNCT
easat-4052	70	17	and	and	CCONJ
easat-4052	70	18	functional	functional	ADJ
easat-4052	70	19	recovery	recovery	NOUN
easat-4052	70	20	in	in	ADP
easat-4052	70	21	patients	patient	NOUN
easat-4052	70	22	with	with	ADP
easat-4052	70	23	knee	knee	NOUN
easat-4052	70	24	oa	oa	NOUN
easat-4052	70	25	and	and	CCONJ
easat-4052	70	26	cartilage	cartilage	NOUN
easat-4052	70	27	defects	defect	NOUN
easat-4052	70	28	.	.	PUNCT
easat-4052	71	1	nevertheless	nevertheless	ADV
easat-4052	71	2	,	,	PUNCT
easat-4052	71	3	the	the	DET
easat-4052	71	4	review	review	NOUN
easat-4052	71	5	underscores	underscore	VERB
easat-4052	71	6	the	the	DET
easat-4052	71	7	importance	importance	NOUN
easat-4052	71	8	of	of	ADP
easat-4052	71	9	establishing	establish	VERB
easat-4052	71	10	standardized	standardized	ADJ
easat-4052	71	11	treatment	treatment	NOUN
easat-4052	71	12	protocols	protocol	NOUN
easat-4052	71	13	,	,	PUNCT
easat-4052	71	14	refining	refining	NOUN
easat-4052	71	15	delivery	delivery	NOUN
easat-4052	71	16	methods	method	NOUN
easat-4052	71	17	,	,	PUNCT
easat-4052	71	18	and	and	CCONJ
easat-4052	71	19	conducting	conduct	VERB
easat-4052	71	20	long	long	ADJ
easat-4052	71	21	-	-	PUNCT
easat-4052	71	22	term	term	NOUN
easat-4052	71	23	follow	follow	NOUN
easat-4052	71	24	-	-	PUNCT
easat-4052	71	25	up	up	ADP
easat-4052	71	26	studies	study	NOUN
easat-4052	71	27	to	to	PART
easat-4052	71	28	realize	realize	VERB
easat-4052	71	29	the	the	DET
easat-4052	71	30	benefits	benefit	NOUN
easat-4052	71	31	of	of	ADP
easat-4052	71	32	admscs	admscs	NOUN
easat-4052	71	33	in	in	ADP
easat-4052	71	34	cartilage	cartilage	NOUN
easat-4052	71	35	regeneration	regeneration	NOUN
easat-4052	71	36	fully	fully	ADV
easat-4052	71	37	[	[	X
easat-4052	71	38	17	17	NUM
easat-4052	71	39	]	]	PUNCT
easat-4052	71	40	.	.	PUNCT
easat-4052	72	1	the	the	DET
easat-4052	72	2	metaanalysis	metaanalysis	NOUN
easat-4052	72	3	by	by	ADP
easat-4052	72	4	meng	meng	PROPN
easat-4052	72	5	et	et	PROPN
easat-4052	72	6	al	al	PROPN
easat-4052	72	7	.	.	PROPN
easat-4052	72	8	(	(	PUNCT
easat-4052	72	9	2021	2021	NUM
easat-4052	72	10	)	)	PUNCT
easat-4052	72	11	concluded	conclude	VERB
easat-4052	72	12	that	that	SCONJ
easat-4052	72	13	administering	administer	VERB
easat-4052	72	14	admscs	admscs	NOUN
easat-4052	72	15	or	or	CCONJ
easat-4052	72	16	stromal	stromal	ADJ
easat-4052	72	17	vascular	vascular	ADJ
easat-4052	72	18	fraction	fraction	NOUN
easat-4052	72	19	(	(	PUNCT
easat-4052	72	20	svf	svf	NOUN
easat-4052	72	21	)	)	PUNCT
easat-4052	72	22	resulted	result	VERB
easat-4052	72	23	in	in	ADP
easat-4052	72	24	improvements	improvement	NOUN
easat-4052	72	25	in	in	ADP
easat-4052	72	26	clinical	clinical	ADJ
easat-4052	72	27	,	,	PUNCT
easat-4052	72	28	imaging	imaging	NOUN
easat-4052	72	29	,	,	PUNCT
easat-4052	72	30	and	and	CCONJ
easat-4052	72	31	histological	histological	ADJ
easat-4052	72	32	outcomes	outcome	NOUN
easat-4052	72	33	,	,	PUNCT
easat-4052	72	34	with	with	SCONJ
easat-4052	72	35	no	no	DET
easat-4052	72	36	severe	severe	ADJ
easat-4052	72	37	adverse	adverse	ADJ
easat-4052	72	38	events	event	NOUN
easat-4052	72	39	reported	report	VERB
easat-4052	72	40	.	.	PUNCT
easat-4052	73	1	although	although	SCONJ
easat-4052	73	2	the	the	DET
easat-4052	73	3	studies	study	NOUN
easat-4052	73	4	included	include	VERB
easat-4052	73	5	in	in	ADP
easat-4052	73	6	the	the	DET
easat-4052	73	7	analysis	analysis	NOUN
easat-4052	73	8	were	be	AUX
easat-4052	73	9	heterogeneous	heterogeneous	ADJ
easat-4052	73	10	,	,	PUNCT
easat-4052	73	11	the	the	DET
easat-4052	73	12	findings	finding	NOUN
easat-4052	73	13	provide	provide	VERB
easat-4052	73	14	evidence	evidence	NOUN
easat-4052	73	15	supporting	support	VERB
easat-4052	73	16	the	the	DET
easat-4052	73	17	use	use	NOUN
easat-4052	73	18	of	of	ADP
easat-4052	73	19	admscs	admscs	NOUN
easat-4052	73	20	or	or	CCONJ
easat-4052	73	21	svfs	svfs	NOUN
easat-4052	73	22	for	for	ADP
easat-4052	73	23	the	the	DET
easat-4052	73	24	treatment	treatment	NOUN
easat-4052	73	25	of	of	ADP
easat-4052	73	26	focal	focal	ADJ
easat-4052	73	27	cartilage	cartilage	NOUN
easat-4052	73	28	defects	defect	NOUN
easat-4052	73	29	[	[	X
easat-4052	73	30	18	18	NUM
easat-4052	73	31	]	]	PUNCT
easat-4052	73	32	.	.	PUNCT
easat-4052	74	1	song	song	PROPN
easat-4052	74	2	et	et	PROPN
easat-4052	74	3	al	al	PROPN
easat-4052	74	4	.	.	PUNCT
easat-4052	75	1	(	(	PUNCT
easat-4052	75	2	2016	2016	NUM
easat-4052	75	3	)	)	PUNCT
easat-4052	75	4	developed	develop	VERB
easat-4052	75	5	a	a	DET
easat-4052	75	6	3d	3d	NOUN
easat-4052	75	7	bilayered	bilayere	VERB
easat-4052	75	8	osteochondral	osteochondral	ADJ
easat-4052	75	9	(	(	PUNCT
easat-4052	75	10	oc	oc	NOUN
easat-4052	75	11	)	)	PUNCT
easat-4052	75	12	construct	construct	VERB
easat-4052	75	13	incorporating	incorporate	VERB
easat-4052	75	14	adsmc	adsmc	NOUN
easat-4052	75	15	to	to	PART
easat-4052	75	16	treat	treat	VERB
easat-4052	75	17	large	large	ADJ
easat-4052	75	18	oc	oc	NOUN
easat-4052	75	19	defects	defect	NOUN
easat-4052	75	20	.	.	PUNCT
easat-4052	76	1	this	this	DET
easat-4052	76	2	composite	composite	ADJ
easat-4052	76	3	scaffold	scaffold	NOUN
easat-4052	76	4	consisted	consist	VERB
easat-4052	76	5	of	of	ADP
easat-4052	76	6	porcine	porcine	NOUN
easat-4052	76	7	cancellous	cancellous	ADJ
easat-4052	76	8	bone	bone	NOUN
easat-4052	76	9	and	and	CCONJ
easat-4052	76	10	a	a	DET
easat-4052	76	11	chitosan	chitosan	NOUN
easat-4052	76	12	/	/	SYM
easat-4052	76	13	gelatin	gelatin	NOUN
easat-4052	76	14	hydrogel	hydrogel	NOUN
easat-4052	76	15	placed	place	VERB
easat-4052	76	16	on	on	ADP
easat-4052	76	17	opposite	opposite	ADJ
easat-4052	76	18	sides	side	NOUN
easat-4052	76	19	to	to	PART
easat-4052	76	20	facilitate	facilitate	VERB
easat-4052	76	21	bone	bone	NOUN
easat-4052	76	22	and	and	CCONJ
easat-4052	76	23	cartilage	cartilage	NOUN
easat-4052	76	24	regeneration	regeneration	NOUN
easat-4052	76	25	,	,	PUNCT
easat-4052	76	26	respectively	respectively	ADV
easat-4052	76	27	.	.	PUNCT
easat-4052	77	1	admscs	admscs	PROPN
easat-4052	77	2	were	be	AUX
easat-4052	77	3	seeded	seed	VERB
easat-4052	77	4	in	in	ADP
easat-4052	77	5	the	the	DET
easat-4052	77	6	hydrogel	hydrogel	NOUN
easat-4052	77	7	to	to	PART
easat-4052	77	8	promote	promote	VERB
easat-4052	77	9	chondrocyte	chondrocyte	NOUN
easat-4052	77	10	-	-	PUNCT
easat-4052	77	11	like	like	ADJ
easat-4052	77	12	differentiation	differentiation	NOUN
easat-4052	77	13	and	and	CCONJ
easat-4052	77	14	in	in	ADP
easat-4052	77	15	the	the	DET
easat-4052	77	16	cancellous	cancellous	ADJ
easat-4052	77	17	bone	bone	NOUN
easat-4052	77	18	to	to	PART
easat-4052	77	19	support	support	VERB
easat-4052	77	20	osteoblast	osteoblast	ADJ
easat-4052	77	21	-	-	PUNCT
easat-4052	77	22	like	like	ADJ
easat-4052	77	23	differentiation	differentiation	NOUN
easat-4052	77	24	.	.	PUNCT
easat-4052	78	1	the	the	DET
easat-4052	78	2	study	study	NOUN
easat-4052	78	3	demonstrated	demonstrate	VERB
easat-4052	78	4	that	that	SCONJ
easat-4052	78	5	the	the	DET
easat-4052	78	6	bilayered	bilayere	VERB
easat-4052	78	7	scaffold	scaffold	NOUN
easat-4052	78	8	significantly	significantly	ADV
easat-4052	78	9	enhanced	enhance	VERB
easat-4052	78	10	admsc	admsc	NOUN
easat-4052	78	11	proliferation	proliferation	NOUN
easat-4052	78	12	through	through	ADP
easat-4052	78	13	intercellular	intercellular	ADJ
easat-4052	78	14	interactions	interaction	NOUN
easat-4052	78	15	,	,	PUNCT
easat-4052	78	16	outperforming	outperform	VERB
easat-4052	78	17	single	single	ADJ
easat-4052	78	18	-	-	PUNCT
easat-4052	78	19	layer	layer	NOUN
easat-4052	78	20	scaffolds	scaffold	NOUN
easat-4052	78	21	[	[	X
easat-4052	78	22	19	19	NUM
easat-4052	78	23	]	]	PUNCT
easat-4052	78	24	.	.	PUNCT
easat-4052	79	1	additionally	additionally	ADV
easat-4052	79	2	,	,	PUNCT
easat-4052	79	3	a	a	DET
easat-4052	79	4	rabbit	rabbit	NOUN
easat-4052	79	5	model	model	NOUN
easat-4052	79	6	of	of	ADP
easat-4052	79	7	oc	oc	ADP
easat-4052	79	8	defects	defect	NOUN
easat-4052	79	9	was	be	AUX
easat-4052	79	10	used	use	VERB
easat-4052	79	11	to	to	PART
easat-4052	79	12	test	test	VERB
easat-4052	79	13	a	a	DET
easat-4052	79	14	poly(l	poly(l	ADJ
easat-4052	79	15	-	-	PUNCT
easat-4052	79	16	glutamic	glutamic	ADJ
easat-4052	79	17	acid)-based	acid)-base	VERB
easat-4052	79	18	bilayer	bilayer	NOUN
easat-4052	79	19	scaffold	scaffold	NOUN
easat-4052	79	20	combined	combine	VERB
easat-4052	79	21	with	with	ADP
easat-4052	79	22	autologous	autologous	ADJ
easat-4052	79	23	admscs	admscs	NOUN
easat-4052	79	24	for	for	ADP
easat-4052	79	25	simultaneous	simultaneous	ADJ
easat-4052	79	26	regeneration	regeneration	NOUN
easat-4052	79	27	of	of	ADP
easat-4052	79	28	hyaline	hyaline	NOUN
easat-4052	79	29	-	-	PUNCT
easat-4052	79	30	like	like	ADJ
easat-4052	79	31	cartilage	cartilage	NOUN
easat-4052	79	32	and	and	CCONJ
easat-4052	79	33	subchondral	subchondral	ADJ
easat-4052	79	34	bone	bone	NOUN
easat-4052	79	35	.	.	PUNCT
easat-4052	80	1	in	in	ADP
easat-4052	80	2	this	this	DET
easat-4052	80	3	design	design	NOUN
easat-4052	80	4	,	,	PUNCT
easat-4052	80	5	bmp-2	bmp-2	PUNCT
easat-4052	80	6	was	be	AUX
easat-4052	80	7	used	use	VERB
easat-4052	80	8	in	in	ADP
easat-4052	80	9	the	the	DET
easat-4052	80	10	lower	low	ADJ
easat-4052	80	11	region	region	NOUN
easat-4052	80	12	to	to	PART
easat-4052	80	13	induce	induce	VERB
easat-4052	80	14	osteogenesis	osteogenesis	NOUN
easat-4052	80	15	,	,	PUNCT
easat-4052	80	16	while	while	SCONJ
easat-4052	80	17	tgf	tgf	PROPN
easat-4052	80	18	-	-	PUNCT
easat-4052	80	19	β1	β1	PROPN
easat-4052	80	20	and	and	CCONJ
easat-4052	80	21	insulin	insulin	NOUN
easat-4052	80	22	-	-	PUNCT
easat-4052	80	23	like	like	ADJ
easat-4052	80	24	growth	growth	NOUN
easat-4052	80	25	factor-1	factor-1	PROPN
easat-4052	80	26	(	(	PUNCT
easat-4052	80	27	igf-1	igf-1	NOUN
easat-4052	80	28	)	)	PUNCT
easat-4052	80	29	,	,	PUNCT
easat-4052	80	30	were	be	AUX
easat-4052	80	31	applied	apply	VERB
easat-4052	80	32	to	to	ADP
easat-4052	80	33	the	the	DET
easat-4052	80	34	upper	upper	ADJ
easat-4052	80	35	region	region	NOUN
easat-4052	80	36	to	to	PART
easat-4052	80	37	induce	induce	VERB
easat-4052	80	38	chondrogenesis	chondrogenesis	NOUN
easat-4052	80	39	,	,	PUNCT
easat-4052	80	40	promoting	promote	VERB
easat-4052	80	41	the	the	DET
easat-4052	80	42	aggregation	aggregation	NOUN
easat-4052	80	43	of	of	ADP
easat-4052	80	44	admscs	admscs	NOUN
easat-4052	80	45	into	into	ADP
easat-4052	80	46	multicellular	multicellular	ADJ
easat-4052	80	47	spheroids	spheroid	NOUN
easat-4052	80	48	.	.	PUNCT
easat-4052	81	1	upon	upon	SCONJ
easat-4052	81	2	implantation	implantation	NOUN
easat-4052	81	3	into	into	ADP
easat-4052	81	4	the	the	DET
easat-4052	81	5	knee	knee	NOUN
easat-4052	81	6	's	's	PART
easat-4052	81	7	patellofemoral	patellofemoral	ADJ
easat-4052	81	8	groove	groove	NOUN
easat-4052	81	9	,	,	PUNCT
easat-4052	81	10	scaffolds	scaffold	NOUN
easat-4052	81	11	with	with	ADP
easat-4052	81	12	bmp-2	bmp-2	NUM
easat-4052	81	13	and	and	CCONJ
easat-4052	81	14	preinduced	preinduce	VERB
easat-4052	81	15	admsc	admsc	NOUN
easat-4052	81	16	spheroids	spheroid	NOUN
easat-4052	81	17	successfully	successfully	ADV
easat-4052	81	18	regenerated	regenerate	VERB
easat-4052	81	19	both	both	DET
easat-4052	81	20	cartilage	cartilage	NOUN
easat-4052	81	21	and	and	CCONJ
easat-4052	81	22	subchondral	subchondral	ADJ
easat-4052	81	23	bone	bone	NOUN
easat-4052	81	24	after	after	ADP
easat-4052	81	25	12	12	NUM
easat-4052	81	26	weeks	week	NOUN
easat-4052	81	27	.	.	PUNCT
easat-4052	82	1	in	in	ADP
easat-4052	82	2	9595	9595	NUM
easat-4052	82	3	edelweiss	edelweiss	PROPN
easat-4052	82	4	applied	apply	VERB
easat-4052	82	5	science	science	NOUN
easat-4052	82	6	and	and	CCONJ
easat-4052	82	7	technology	technology	NOUN
easat-4052	82	8	issn	issn	PROPN
easat-4052	82	9	:	:	PUNCT
easat-4052	82	10	2576	2576	NUM
easat-4052	82	11	-	-	SYM
easat-4052	82	12	8484	8484	NUM
easat-4052	82	13	vol	vol	NOUN
easat-4052	82	14	.	.	PROPN
easat-4052	82	15	8	8	NUM
easat-4052	82	16	,	,	PUNCT
easat-4052	82	17	no	no	INTJ
easat-4052	82	18	.	.	NOUN
easat-4052	82	19	6	6	NUM
easat-4052	82	20	:	:	SYM
easat-4052	82	21	9592	9592	NUM
easat-4052	82	22	-	-	SYM
easat-4052	82	23	9604	9604	NUM
easat-4052	82	24	,	,	PUNCT
easat-4052	82	25	2024	2024	NUM
easat-4052	82	26	doi	doi	NOUN
easat-4052	82	27	:	:	PUNCT
easat-4052	82	28	10.55214/25768484.v8i6.4052	10.55214/25768484.v8i6.4052	NUM
easat-4052	82	29	©	©	ADP
easat-4052	82	30	2024	2024	NUM
easat-4052	82	31	by	by	ADP
easat-4052	82	32	the	the	DET
easat-4052	82	33	authors	author	NOUN
easat-4052	82	34	;	;	PUNCT
easat-4052	82	35	licensee	licensee	PROPN
easat-4052	82	36	learning	learning	PROPN
easat-4052	82	37	gate	gate	PROPN
easat-4052	82	38	comparison	comparison	NOUN
easat-4052	82	39	,	,	PUNCT
easat-4052	82	40	scaffolds	scaffold	NOUN
easat-4052	82	41	with	with	ADP
easat-4052	82	42	only	only	ADV
easat-4052	82	43	bmp-2	bmp-2	PUNCT
easat-4052	82	44	showed	show	VERB
easat-4052	82	45	limited	limited	ADJ
easat-4052	82	46	regeneration	regeneration	NOUN
easat-4052	82	47	,	,	PUNCT
easat-4052	82	48	promoting	promote	VERB
easat-4052	82	49	subchondral	subchondral	ADJ
easat-4052	82	50	bone	bone	NOUN
easat-4052	82	51	repair	repair	NOUN
easat-4052	82	52	,	,	PUNCT
easat-4052	82	53	while	while	SCONJ
easat-4052	82	54	bare	bare	ADJ
easat-4052	82	55	scaffolds	scaffold	NOUN
easat-4052	82	56	resulted	result	VERB
easat-4052	82	57	in	in	ADP
easat-4052	82	58	poor	poor	ADJ
easat-4052	82	59	tissue	tissue	NOUN
easat-4052	82	60	regeneration	regeneration	NOUN
easat-4052	82	61	overall	overall	ADV
easat-4052	82	62	[	[	X
easat-4052	82	63	20	20	NUM
easat-4052	82	64	]	]	PUNCT
easat-4052	82	65	.	.	PUNCT
easat-4052	83	1	a	a	DET
easat-4052	83	2	recent	recent	ADJ
easat-4052	83	3	study	study	NOUN
easat-4052	83	4	investigated	investigate	VERB
easat-4052	83	5	the	the	DET
easat-4052	83	6	use	use	NOUN
easat-4052	83	7	of	of	ADP
easat-4052	83	8	3d	3d	NOUN
easat-4052	83	9	-	-	PUNCT
easat-4052	83	10	printed	print	VERB
easat-4052	83	11	full	full	ADJ
easat-4052	83	12	-	-	PUNCT
easat-4052	83	13	thickness	thickness	NOUN
easat-4052	83	14	scaffolds	scaffold	NOUN
easat-4052	83	15	for	for	ADP
easat-4052	83	16	treating	treat	VERB
easat-4052	83	17	oc	oc	ADP
easat-4052	83	18	defects	defect	NOUN
easat-4052	83	19	in	in	ADP
easat-4052	83	20	the	the	DET
easat-4052	83	21	trochlear	trochlear	PROPN
easat-4052	83	22	grooves	groove	NOUN
easat-4052	83	23	of	of	ADP
easat-4052	83	24	minipigs	minipig	NOUN
easat-4052	83	25	.	.	PUNCT
easat-4052	84	1	the	the	DET
easat-4052	84	2	researchers	researcher	NOUN
easat-4052	84	3	developed	develop	VERB
easat-4052	84	4	bilayer	bilayer	NOUN
easat-4052	84	5	scaffolds	scaffold	NOUN
easat-4052	84	6	by	by	ADP
easat-4052	84	7	incorporating	incorporate	VERB
easat-4052	84	8	tricalcium	tricalcium	NOUN
easat-4052	84	9	phosphate	phosphate	NOUN
easat-4052	84	10	(	(	PUNCT
easat-4052	84	11	tcp	tcp	PROPN
easat-4052	84	12	)	)	PUNCT
easat-4052	84	13	within	within	ADP
easat-4052	84	14	a	a	DET
easat-4052	84	15	polycaprolactone	polycaprolactone	NOUN
easat-4052	84	16	(	(	PUNCT
easat-4052	84	17	pcl	pcl	PROPN
easat-4052	84	18	)	)	PUNCT
easat-4052	84	19	base	base	NOUN
easat-4052	84	20	to	to	PART
easat-4052	84	21	promote	promote	VERB
easat-4052	84	22	osteogenic	osteogenic	ADJ
easat-4052	84	23	differentiation	differentiation	NOUN
easat-4052	84	24	on	on	ADP
easat-4052	84	25	the	the	DET
easat-4052	84	26	bottom	bottom	ADJ
easat-4052	84	27	layer	layer	NOUN
easat-4052	84	28	,	,	PUNCT
easat-4052	84	29	while	while	SCONJ
easat-4052	84	30	decellularized	decellularize	VERB
easat-4052	84	31	bovine	bovine	NOUN
easat-4052	84	32	cartilage	cartilage	NOUN
easat-4052	84	33	ecm	ecm	NOUN
easat-4052	84	34	was	be	AUX
easat-4052	84	35	placed	place	VERB
easat-4052	84	36	on	on	ADP
easat-4052	84	37	the	the	DET
easat-4052	84	38	superficial	superficial	ADJ
easat-4052	84	39	side	side	NOUN
easat-4052	84	40	to	to	PART
easat-4052	84	41	facilitate	facilitate	VERB
easat-4052	84	42	chondrogenesis	chondrogenesis	NOUN
easat-4052	84	43	in	in	ADP
easat-4052	84	44	admscs	admsc	NOUN
easat-4052	84	45	.	.	PUNCT
easat-4052	85	1	additionally	additionally	ADV
easat-4052	85	2	,	,	PUNCT
easat-4052	85	3	an	an	DET
easat-4052	85	4	electrospun	electrospun	NOUN
easat-4052	85	5	disk	disk	NOUN
easat-4052	85	6	was	be	AUX
easat-4052	85	7	inserted	insert	VERB
easat-4052	85	8	between	between	ADP
easat-4052	85	9	the	the	DET
easat-4052	85	10	two	two	NUM
easat-4052	85	11	layers	layer	NOUN
easat-4052	85	12	to	to	PART
easat-4052	85	13	replicate	replicate	VERB
easat-4052	85	14	the	the	DET
easat-4052	85	15	natural	natural	ADJ
easat-4052	85	16	tidemark	tidemark	NOUN
easat-4052	85	17	,	,	PUNCT
easat-4052	85	18	preventing	prevent	VERB
easat-4052	85	19	blood	blood	NOUN
easat-4052	85	20	vessel	vessel	NOUN
easat-4052	85	21	infiltration	infiltration	NOUN
easat-4052	85	22	and	and	CCONJ
easat-4052	85	23	ossification	ossification	NOUN
easat-4052	85	24	in	in	ADP
easat-4052	85	25	the	the	DET
easat-4052	85	26	cartilage	cartilage	NOUN
easat-4052	85	27	layer	layer	NOUN
easat-4052	85	28	.	.	PUNCT
easat-4052	86	1	five	five	NUM
easat-4052	86	2	experimental	experimental	ADJ
easat-4052	86	3	conditions	condition	NOUN
easat-4052	86	4	were	be	AUX
easat-4052	86	5	tested	test	VERB
easat-4052	86	6	:	:	PUNCT
easat-4052	86	7	(	(	PUNCT
easat-4052	86	8	a	a	X
easat-4052	86	9	)	)	PUNCT
easat-4052	86	10	open	open	ADJ
easat-4052	86	11	lesion	lesion	NOUN
easat-4052	86	12	defects	defect	NOUN
easat-4052	86	13	as	as	ADP
easat-4052	86	14	a	a	DET
easat-4052	86	15	negative	negative	ADJ
easat-4052	86	16	control	control	NOUN
easat-4052	86	17	,	,	PUNCT
easat-4052	86	18	(	(	PUNCT
easat-4052	86	19	b	b	X
easat-4052	86	20	)	)	PUNCT
easat-4052	86	21	acellular	acellular	ADJ
easat-4052	86	22	scaffolds	scaffold	NOUN
easat-4052	86	23	without	without	ADP
easat-4052	86	24	tidemarks	tidemark	NOUN
easat-4052	86	25	,	,	PUNCT
easat-4052	86	26	(	(	PUNCT
easat-4052	86	27	c	c	X
easat-4052	86	28	)	)	PUNCT
easat-4052	86	29	acellular	acellular	ADJ
easat-4052	86	30	scaffolds	scaffold	NOUN
easat-4052	86	31	with	with	ADP
easat-4052	86	32	tidemarks	tidemark	NOUN
easat-4052	86	33	,	,	PUNCT
easat-4052	86	34	(	(	PUNCT
easat-4052	86	35	d	d	X
easat-4052	86	36	)	)	PUNCT
easat-4052	86	37	admsc	admsc	NOUN
easat-4052	86	38	-	-	PUNCT
easat-4052	86	39	seeded	seeded	ADJ
easat-4052	86	40	scaffolds	scaffold	NOUN
easat-4052	86	41	,	,	PUNCT
easat-4052	86	42	and	and	CCONJ
easat-4052	86	43	(	(	PUNCT
easat-4052	86	44	e	e	NOUN
easat-4052	86	45	)	)	PUNCT
easat-4052	86	46	autologous	autologous	ADJ
easat-4052	86	47	explants	explant	NOUN
easat-4052	86	48	as	as	ADP
easat-4052	86	49	a	a	DET
easat-4052	86	50	positive	positive	ADJ
easat-4052	86	51	control	control	NOUN
easat-4052	86	52	.	.	PUNCT
easat-4052	87	1	after	after	ADP
easat-4052	87	2	four	four	NUM
easat-4052	87	3	months	month	NOUN
easat-4052	87	4	,	,	PUNCT
easat-4052	87	5	autologous	autologous	ADJ
easat-4052	87	6	explants	explant	NOUN
easat-4052	87	7	yielded	yield	VERB
easat-4052	87	8	the	the	DET
easat-4052	87	9	best	good	ADJ
easat-4052	87	10	results	result	NOUN
easat-4052	87	11	,	,	PUNCT
easat-4052	87	12	while	while	SCONJ
easat-4052	87	13	admsc	admsc	NOUN
easat-4052	87	14	-	-	PUNCT
easat-4052	87	15	seeded	seeded	ADJ
easat-4052	87	16	scaffolds	scaffold	NOUN
easat-4052	87	17	closely	closely	ADV
easat-4052	87	18	resembled	resemble	VERB
easat-4052	87	19	the	the	DET
easat-4052	87	20	positive	positive	ADJ
easat-4052	87	21	control	control	NOUN
easat-4052	87	22	.	.	PUNCT
easat-4052	88	1	in	in	ADP
easat-4052	88	2	contrast	contrast	NOUN
easat-4052	88	3	,	,	PUNCT
easat-4052	88	4	open	open	ADJ
easat-4052	88	5	lesions	lesion	NOUN
easat-4052	88	6	showed	show	VERB
easat-4052	88	7	disorganized	disorganized	ADJ
easat-4052	88	8	repair	repair	NOUN
easat-4052	88	9	tissue	tissue	NOUN
easat-4052	88	10	and	and	CCONJ
easat-4052	88	11	acellular	acellular	ADJ
easat-4052	88	12	scaffolds	scaffold	NOUN
easat-4052	88	13	promoted	promote	VERB
easat-4052	88	14	subchondral	subchondral	ADJ
easat-4052	88	15	bone	bone	NOUN
easat-4052	88	16	regeneration	regeneration	NOUN
easat-4052	88	17	.	.	PUNCT
easat-4052	89	1	the	the	DET
easat-4052	89	2	scaffold	scaffold	NOUN
easat-4052	89	3	without	without	ADP
easat-4052	89	4	the	the	DET
easat-4052	89	5	tidemark	tidemark	NOUN
easat-4052	89	6	more	more	ADV
easat-4052	89	7	effectively	effectively	ADV
easat-4052	89	8	filled	fill	VERB
easat-4052	89	9	the	the	DET
easat-4052	89	10	lesion	lesion	NOUN
easat-4052	89	11	but	but	CCONJ
easat-4052	89	12	inhibited	inhibited	ADJ
easat-4052	89	13	native	native	ADJ
easat-4052	89	14	cell	cell	NOUN
easat-4052	89	15	migration	migration	NOUN
easat-4052	89	16	and	and	CCONJ
easat-4052	89	17	cartilage	cartilage	NOUN
easat-4052	89	18	regeneration	regeneration	NOUN
easat-4052	89	19	[	[	X
easat-4052	89	20	21	21	NUM
easat-4052	89	21	]	]	PUNCT
easat-4052	89	22	.	.	PUNCT
easat-4052	90	1	further	further	PROPN
easat-4052	90	2	studies	study	NOUN
easat-4052	90	3	also	also	ADV
easat-4052	90	4	explored	explore	VERB
easat-4052	90	5	the	the	DET
easat-4052	90	6	use	use	NOUN
easat-4052	90	7	of	of	ADP
easat-4052	90	8	human	human	ADJ
easat-4052	90	9	umbilical	umbilical	ADJ
easat-4052	90	10	cord	cord	NOUN
easat-4052	90	11	blood	blood	NOUN
easat-4052	90	12	mscs	msc	NOUN
easat-4052	90	13	seeded	seed	VERB
easat-4052	90	14	in	in	ADP
easat-4052	90	15	bilayer	bilayer	NOUN
easat-4052	90	16	scaffolds	scaffold	NOUN
easat-4052	90	17	consisting	consist	VERB
easat-4052	90	18	of	of	ADP
easat-4052	90	19	hyaluronic	hyaluronic	ADJ
easat-4052	90	20	acid	acid	NOUN
easat-4052	90	21	(	(	PUNCT
easat-4052	90	22	ha	ha	INTJ
easat-4052	90	23	)	)	PUNCT
easat-4052	90	24	and	and	CCONJ
easat-4052	90	25	gelatinbased	gelatinbase	VERB
easat-4052	90	26	microcrystals	microcrystal	NOUN
easat-4052	90	27	to	to	PART
easat-4052	90	28	promote	promote	VERB
easat-4052	90	29	bone	bone	NOUN
easat-4052	90	30	and	and	CCONJ
easat-4052	90	31	cartilage	cartilage	NOUN
easat-4052	90	32	regeneration	regeneration	NOUN
easat-4052	90	33	,	,	PUNCT
easat-4052	90	34	respectively	respectively	ADV
easat-4052	90	35	.	.	PUNCT
easat-4052	91	1	in	in	ADP
easat-4052	91	2	a	a	DET
easat-4052	91	3	dog	dog	NOUN
easat-4052	91	4	model	model	NOUN
easat-4052	91	5	with	with	ADP
easat-4052	91	6	oc	oc	ADP
easat-4052	91	7	defects	defect	NOUN
easat-4052	91	8	in	in	ADP
easat-4052	91	9	the	the	DET
easat-4052	91	10	femoral	femoral	ADJ
easat-4052	91	11	trochlear	trochlear	PROPN
easat-4052	91	12	groove	groove	NOUN
easat-4052	91	13	,	,	PUNCT
easat-4052	91	14	these	these	DET
easat-4052	91	15	scaffolds	scaffold	NOUN
easat-4052	91	16	successfully	successfully	ADV
easat-4052	91	17	filled	fill	VERB
easat-4052	91	18	the	the	DET
easat-4052	91	19	defects	defect	NOUN
easat-4052	91	20	with	with	ADP
easat-4052	91	21	newly	newly	ADV
easat-4052	91	22	formed	form	VERB
easat-4052	91	23	tissue	tissue	NOUN
easat-4052	91	24	,	,	PUNCT
easat-4052	91	25	exhibiting	exhibit	VERB
easat-4052	91	26	a	a	DET
easat-4052	91	27	biphasic	biphasic	ADJ
easat-4052	91	28	structure	structure	NOUN
easat-4052	91	29	of	of	ADP
easat-4052	91	30	bone	bone	NOUN
easat-4052	91	31	and	and	CCONJ
easat-4052	91	32	cartilage	cartilage	NOUN
easat-4052	91	33	[	[	X
easat-4052	91	34	22	22	NUM
easat-4052	91	35	]	]	PUNCT
easat-4052	91	36	.	.	PUNCT
easat-4052	92	1	a	a	DET
easat-4052	92	2	systematic	systematic	ADJ
easat-4052	92	3	review	review	NOUN
easat-4052	92	4	by	by	ADP
easat-4052	92	5	issa	issa	PROPN
easat-4052	92	6	et	et	PROPN
easat-4052	92	7	al	al	PROPN
easat-4052	92	8	.	.	PROPN
easat-4052	92	9	(	(	PUNCT
easat-4052	92	10	2022	2022	NUM
easat-4052	92	11	)	)	PUNCT
easat-4052	92	12	demonstrated	demonstrate	VERB
easat-4052	92	13	that	that	SCONJ
easat-4052	92	14	admscs	admscs	NOUN
easat-4052	92	15	are	be	AUX
easat-4052	92	16	effective	effective	ADJ
easat-4052	92	17	in	in	ADP
easat-4052	92	18	alleviating	alleviate	VERB
easat-4052	92	19	knee	knee	NOUN
easat-4052	92	20	oa	oa	NOUN
easat-4052	92	21	symptoms	symptom	NOUN
easat-4052	92	22	,	,	PUNCT
easat-4052	92	23	as	as	SCONJ
easat-4052	92	24	evidenced	evidence	VERB
easat-4052	92	25	by	by	ADP
easat-4052	92	26	significant	significant	ADJ
easat-4052	92	27	improvements	improvement	NOUN
easat-4052	92	28	in	in	ADP
easat-4052	92	29	both	both	PRON
easat-4052	92	30	function	function	NOUN
easat-4052	92	31	and	and	CCONJ
easat-4052	92	32	pain	pain	NOUN
easat-4052	92	33	levels	level	NOUN
easat-4052	92	34	.	.	PUNCT
easat-4052	93	1	additionally	additionally	ADV
easat-4052	93	2	,	,	PUNCT
easat-4052	93	3	admsc	admsc	NOUN
easat-4052	93	4	injections	injection	NOUN
easat-4052	93	5	led	lead	VERB
easat-4052	93	6	to	to	ADP
easat-4052	93	7	enhanced	enhanced	ADJ
easat-4052	93	8	cartilage	cartilage	NOUN
easat-4052	93	9	integrity	integrity	NOUN
easat-4052	93	10	,	,	PUNCT
easat-4052	93	11	suggesting	suggest	VERB
easat-4052	93	12	their	their	PRON
easat-4052	93	13	potential	potential	NOUN
easat-4052	93	14	for	for	ADP
easat-4052	93	15	regenerating	regenerate	VERB
easat-4052	93	16	knee	knee	NOUN
easat-4052	93	17	cartilage	cartilage	NOUN
easat-4052	93	18	and	and	CCONJ
easat-4052	93	19	offering	offer	VERB
easat-4052	93	20	a	a	DET
easat-4052	93	21	promising	promise	VERB
easat-4052	93	22	therapeutic	therapeutic	ADJ
easat-4052	93	23	approach	approach	NOUN
easat-4052	93	24	to	to	ADP
easat-4052	93	25	oa	oa	PROPN
easat-4052	93	26	treatment	treatment	NOUN
easat-4052	93	27	[	[	X
easat-4052	93	28	13	13	NUM
easat-4052	93	29	]	]	PUNCT
easat-4052	93	30	.	.	PUNCT
easat-4052	94	1	this	this	PRON
easat-4052	94	2	is	be	AUX
easat-4052	94	3	also	also	ADV
easat-4052	94	4	supported	support	VERB
easat-4052	94	5	by	by	ADP
easat-4052	94	6	studies	study	NOUN
easat-4052	94	7	by	by	ADP
easat-4052	94	8	kangari	kangari	PROPN
easat-4052	94	9	et	et	PROPN
easat-4052	94	10	al	al	PROPN
easat-4052	94	11	.	.	PROPN
easat-4052	95	1	(	(	PUNCT
easat-4052	95	2	2020	2020	NUM
easat-4052	95	3	)	)	PUNCT
easat-4052	95	4	and	and	CCONJ
easat-4052	95	5	zhang	zhang	PROPN
easat-4052	95	6	et	et	PROPN
easat-4052	95	7	al	al	PROPN
easat-4052	95	8	.	.	PROPN
easat-4052	96	1	(	(	PUNCT
easat-4052	96	2	2022	2022	NUM
easat-4052	96	3	)	)	PUNCT
easat-4052	96	4	which	which	PRON
easat-4052	96	5	emphasize	emphasize	VERB
easat-4052	96	6	that	that	PRON
easat-4052	96	7	admscs	admsc	NOUN
easat-4052	96	8	demonstrate	demonstrate	VERB
easat-4052	96	9	significant	significant	ADJ
easat-4052	96	10	regenerative	regenerative	ADJ
easat-4052	96	11	capabilities	capability	NOUN
easat-4052	96	12	in	in	ADP
easat-4052	96	13	preclinical	preclinical	ADJ
easat-4052	96	14	models	model	NOUN
easat-4052	96	15	and	and	CCONJ
easat-4052	96	16	clinical	clinical	ADJ
easat-4052	96	17	trials	trial	NOUN
easat-4052	96	18	,	,	PUNCT
easat-4052	96	19	with	with	ADP
easat-4052	96	20	improvements	improvement	NOUN
easat-4052	96	21	observed	observe	VERB
easat-4052	96	22	in	in	ADP
easat-4052	96	23	tissue	tissue	NOUN
easat-4052	96	24	healing	healing	NOUN
easat-4052	96	25	,	,	PUNCT
easat-4052	96	26	functional	functional	ADJ
easat-4052	96	27	recovery	recovery	NOUN
easat-4052	96	28	,	,	PUNCT
easat-4052	96	29	and	and	CCONJ
easat-4052	96	30	pain	pain	NOUN
easat-4052	96	31	reduction	reduction	NOUN
easat-4052	96	32	[	[	X
easat-4052	96	33	24,25	24,25	NUM
easat-4052	96	34	]	]	PUNCT
easat-4052	96	35	.	.	PUNCT
easat-4052	97	1	the	the	DET
easat-4052	97	2	metaanalysis	metaanalysis	NOUN
easat-4052	97	3	by	by	ADP
easat-4052	97	4	ow	ow	INTJ
easat-4052	97	5	et	et	PROPN
easat-4052	97	6	al	al	PROPN
easat-4052	97	7	.	.	PROPN
easat-4052	97	8	(	(	PUNCT
easat-4052	97	9	2023	2023	NUM
easat-4052	97	10	)	)	PUNCT
easat-4052	97	11	concluded	conclude	VERB
easat-4052	97	12	that	that	SCONJ
easat-4052	97	13	scaffold	scaffold	NOUN
easat-4052	97	14	-	-	PUNCT
easat-4052	97	15	implanted	implant	VERB
easat-4052	97	16	mscs	msc	NOUN
easat-4052	97	17	provide	provide	VERB
easat-4052	97	18	moderately	moderately	ADV
easat-4052	97	19	effective	effective	ADJ
easat-4052	97	20	shortterm	shortterm	NOUN
easat-4052	97	21	outcomes	outcome	NOUN
easat-4052	97	22	in	in	ADP
easat-4052	97	23	the	the	DET
easat-4052	97	24	repair	repair	NOUN
easat-4052	97	25	of	of	ADP
easat-4052	97	26	knee	knee	NOUN
easat-4052	97	27	chondral	chondral	ADJ
easat-4052	97	28	defects	defect	NOUN
easat-4052	97	29	.	.	PUNCT
easat-4052	98	1	the	the	DET
easat-4052	98	2	analysis	analysis	NOUN
easat-4052	98	3	showed	show	VERB
easat-4052	98	4	notable	notable	ADJ
easat-4052	98	5	improvements	improvement	NOUN
easat-4052	98	6	in	in	ADP
easat-4052	98	7	cartilage	cartilage	NOUN
easat-4052	98	8	repair	repair	NOUN
easat-4052	98	9	,	,	PUNCT
easat-4052	98	10	functional	functional	ADJ
easat-4052	98	11	recovery	recovery	NOUN
easat-4052	98	12	,	,	PUNCT
easat-4052	98	13	and	and	CCONJ
easat-4052	98	14	pain	pain	NOUN
easat-4052	98	15	reduction	reduction	NOUN
easat-4052	98	16	,	,	PUNCT
easat-4052	98	17	suggesting	suggest	VERB
easat-4052	98	18	that	that	SCONJ
easat-4052	98	19	scaffold	scaffold	NOUN
easat-4052	98	20	-	-	PUNCT
easat-4052	98	21	implanted	implant	VERB
easat-4052	98	22	mscs	msc	NOUN
easat-4052	98	23	are	be	AUX
easat-4052	98	24	a	a	DET
easat-4052	98	25	promising	promising	ADJ
easat-4052	98	26	therapeutic	therapeutic	ADJ
easat-4052	98	27	approach	approach	NOUN
easat-4052	98	28	for	for	ADP
easat-4052	98	29	managing	manage	VERB
easat-4052	98	30	knee	knee	NOUN
easat-4052	98	31	chondral	chondral	ADJ
easat-4052	98	32	defects	defect	NOUN
easat-4052	98	33	in	in	ADP
easat-4052	98	34	the	the	DET
easat-4052	98	35	short	short	ADJ
easat-4052	98	36	term	term	NOUN
easat-4052	98	37	.	.	PUNCT
easat-4052	99	1	however	however	ADV
easat-4052	99	2	,	,	PUNCT
easat-4052	99	3	the	the	DET
easat-4052	99	4	study	study	NOUN
easat-4052	99	5	highlights	highlight	VERB
easat-4052	99	6	the	the	DET
easat-4052	99	7	need	need	NOUN
easat-4052	99	8	for	for	ADP
easat-4052	99	9	further	further	ADJ
easat-4052	99	10	investigation	investigation	NOUN
easat-4052	99	11	into	into	ADP
easat-4052	99	12	long	long	ADJ
easat-4052	99	13	-	-	PUNCT
easat-4052	99	14	term	term	NOUN
easat-4052	99	15	outcomes	outcome	NOUN
easat-4052	99	16	to	to	PART
easat-4052	99	17	assess	assess	VERB
easat-4052	99	18	the	the	DET
easat-4052	99	19	sustainability	sustainability	NOUN
easat-4052	99	20	of	of	ADP
easat-4052	99	21	these	these	DET
easat-4052	99	22	benefits	benefit	NOUN
easat-4052	99	23	fully	fully	ADV
easat-4052	99	24	[	[	X
easat-4052	99	25	23	23	NUM
easat-4052	99	26	]	]	PUNCT
easat-4052	99	27	.	.	PUNCT
easat-4052	100	1	recent	recent	ADJ
easat-4052	100	2	advances	advance	NOUN
easat-4052	100	3	in	in	ADP
easat-4052	100	4	biomaterial	biomaterial	NOUN
easat-4052	100	5	-	-	PUNCT
easat-4052	100	6	based	base	VERB
easat-4052	100	7	scaffolds	scaffold	NOUN
easat-4052	100	8	have	have	AUX
easat-4052	100	9	significantly	significantly	ADV
easat-4052	100	10	enhanced	enhance	VERB
easat-4052	100	11	the	the	DET
easat-4052	100	12	promotion	promotion	NOUN
easat-4052	100	13	of	of	ADP
easat-4052	100	14	cartilage	cartilage	NOUN
easat-4052	100	15	regeneration	regeneration	NOUN
easat-4052	100	16	.	.	PUNCT
easat-4052	101	1	these	these	DET
easat-4052	101	2	scaffolds	scaffold	NOUN
easat-4052	101	3	are	be	AUX
easat-4052	101	4	crucial	crucial	ADJ
easat-4052	101	5	in	in	ADP
easat-4052	101	6	providing	provide	VERB
easat-4052	101	7	structural	structural	ADJ
easat-4052	101	8	support	support	NOUN
easat-4052	101	9	,	,	PUNCT
easat-4052	101	10	facilitating	facilitate	VERB
easat-4052	101	11	cell	cell	NOUN
easat-4052	101	12	migration	migration	NOUN
easat-4052	101	13	,	,	PUNCT
easat-4052	101	14	and	and	CCONJ
easat-4052	101	15	improving	improve	VERB
easat-4052	101	16	tissue	tissue	NOUN
easat-4052	101	17	integration	integration	NOUN
easat-4052	101	18	during	during	ADP
easat-4052	101	19	cartilage	cartilage	NOUN
easat-4052	101	20	repair	repair	NOUN
easat-4052	101	21	.	.	PUNCT
easat-4052	102	1	innovations	innovation	NOUN
easat-4052	102	2	in	in	ADP
easat-4052	102	3	natural	natural	ADJ
easat-4052	102	4	and	and	CCONJ
easat-4052	102	5	synthetic	synthetic	ADJ
easat-4052	102	6	materials	material	NOUN
easat-4052	102	7	have	have	AUX
easat-4052	102	8	shown	show	VERB
easat-4052	102	9	great	great	ADJ
easat-4052	102	10	promise	promise	NOUN
easat-4052	102	11	in	in	ADP
easat-4052	102	12	creating	create	VERB
easat-4052	102	13	scaffolds	scaffold	NOUN
easat-4052	102	14	that	that	SCONJ
easat-4052	102	15	closely	closely	ADV
easat-4052	102	16	mimic	mimic	VERB
easat-4052	102	17	the	the	DET
easat-4052	102	18	native	native	ADJ
easat-4052	102	19	ecm	ecm	NOUN
easat-4052	102	20	of	of	ADP
easat-4052	102	21	cartilage	cartilage	NOUN
easat-4052	102	22	.	.	PUNCT
easat-4052	103	1	this	this	DET
easat-4052	103	2	approach	approach	NOUN
easat-4052	103	3	has	have	AUX
easat-4052	103	4	improved	improve	VERB
easat-4052	103	5	cell	cell	NOUN
easat-4052	103	6	differentiation	differentiation	NOUN
easat-4052	103	7	,	,	PUNCT
easat-4052	103	8	matrix	matrix	NOUN
easat-4052	103	9	deposition	deposition	NOUN
easat-4052	103	10	,	,	PUNCT
easat-4052	103	11	and	and	CCONJ
easat-4052	103	12	tissue	tissue	NOUN
easat-4052	103	13	remodeling	remodeling	NOUN
easat-4052	103	14	,	,	PUNCT
easat-4052	103	15	thereby	thereby	ADV
easat-4052	103	16	advancing	advance	VERB
easat-4052	103	17	the	the	DET
easat-4052	103	18	potential	potential	NOUN
easat-4052	103	19	for	for	ADP
easat-4052	103	20	effective	effective	ADJ
easat-4052	103	21	cartilage	cartilage	NOUN
easat-4052	103	22	regeneration	regeneration	NOUN
easat-4052	103	23	[	[	X
easat-4052	103	24	14	14	NUM
easat-4052	103	25	]	]	PUNCT
easat-4052	103	26	.	.	PUNCT
easat-4052	104	1	overall	overall	ADV
easat-4052	104	2	,	,	PUNCT
easat-4052	104	3	a	a	DET
easat-4052	104	4	summary	summary	NOUN
easat-4052	104	5	of	of	ADP
easat-4052	104	6	studies	study	NOUN
easat-4052	104	7	related	relate	VERB
easat-4052	104	8	to	to	ADP
easat-4052	104	9	the	the	DET
easat-4052	104	10	use	use	NOUN
easat-4052	104	11	of	of	ADP
easat-4052	104	12	scaffolds	scaffold	NOUN
easat-4052	104	13	with	with	ADP
easat-4052	104	14	admscs	admscs	NOUN
easat-4052	104	15	in	in	ADP
easat-4052	104	16	knee	knee	NOUN
easat-4052	104	17	cartilage	cartilage	NOUN
easat-4052	104	18	joint	joint	ADJ
easat-4052	104	19	defects	defect	NOUN
easat-4052	104	20	is	be	AUX
easat-4052	104	21	shown	show	VERB
easat-4052	104	22	in	in	ADP
easat-4052	104	23	table	table	NOUN
easat-4052	104	24	1	1	NUM
easat-4052	104	25	.	.	X
easat-4052	104	26	9596	9596	NUM
easat-4052	104	27	edelweiss	edelweiss	PROPN
easat-4052	104	28	applied	apply	VERB
easat-4052	104	29	science	science	NOUN
easat-4052	104	30	and	and	CCONJ
easat-4052	104	31	technology	technology	NOUN
easat-4052	104	32	issn	issn	PROPN
easat-4052	104	33	:	:	PUNCT
easat-4052	104	34	2576	2576	NUM
easat-4052	104	35	-	-	SYM
easat-4052	104	36	8484	8484	NUM
easat-4052	104	37	vol	vol	NOUN
easat-4052	104	38	.	.	PROPN
easat-4052	105	1	8	8	NUM
easat-4052	105	2	,	,	PUNCT
easat-4052	105	3	no	no	INTJ
easat-4052	105	4	.	.	NOUN
easat-4052	106	1	6	6	NUM
easat-4052	106	2	:	:	SYM
easat-4052	106	3	9592	9592	NUM
easat-4052	106	4	-	-	SYM
easat-4052	106	5	9604	9604	NUM
easat-4052	106	6	,	,	PUNCT
easat-4052	106	7	2024	2024	NUM
easat-4052	106	8	doi	doi	NOUN
easat-4052	106	9	:	:	PUNCT
easat-4052	106	10	10.55214/25768484.v8i6.4052	10.55214/25768484.v8i6.4052	NUM
easat-4052	107	1	©	©	ADP
easat-4052	107	2	2024	2024	NUM
easat-4052	107	3	by	by	ADP
easat-4052	107	4	the	the	DET
easat-4052	107	5	authors	author	NOUN
easat-4052	107	6	;	;	PUNCT
easat-4052	107	7	licensee	licensee	PROPN
easat-4052	107	8	learning	learn	VERB
easat-4052	107	9	gate	gate	NOUN
easat-4052	107	10	table	table	NOUN
easat-4052	107	11	1	1	NUM
easat-4052	107	12	.	.	PUNCT
easat-4052	108	1	summary	summary	NOUN
easat-4052	108	2	of	of	ADP
easat-4052	108	3	studies	study	NOUN
easat-4052	108	4	on	on	ADP
easat-4052	108	5	using	use	VERB
easat-4052	108	6	scaffolds	scaffold	NOUN
easat-4052	108	7	with	with	ADP
easat-4052	108	8	admscs	admscs	NOUN
easat-4052	108	9	in	in	ADP
easat-4052	108	10	knee	knee	NOUN
easat-4052	108	11	cartilage	cartilage	NOUN
easat-4052	108	12	joint	joint	ADJ
easat-4052	108	13	defects	defect	NOUN
easat-4052	108	14	.	.	PUNCT
easat-4052	109	1	authors	author	NOUN
easat-4052	109	2	,	,	PUNCT
easat-4052	109	3	year	year	NOUN
easat-4052	109	4	study	study	NOUN
easat-4052	109	5	design	design	NOUN
easat-4052	109	6	models	model	NOUN
easat-4052	109	7	admscs	admscs	NOUN
easat-4052	109	8	harvesting	harvesting	NOUN
easat-4052	109	9	and	and	CCONJ
easat-4052	109	10	isolating	isolate	VERB
easat-4052	109	11	methods	method	NOUN
easat-4052	109	12	scaffolds	scaffold	VERB
easat-4052	109	13	key	key	ADJ
easat-4052	109	14	findings	finding	NOUN
easat-4052	109	15	perdisa	perdisa	NOUN
easat-4052	109	16	et	et	NOUN
easat-4052	109	17	al	al	PROPN
easat-4052	109	18	.	.	PROPN
easat-4052	109	19	,	,	PUNCT
easat-4052	109	20	2015	2015	NUM
easat-4052	110	1	[	[	X
easat-4052	110	2	17	17	NUM
easat-4052	110	3	]	]	X
easat-4052	110	4	systematic	systematic	ADJ
easat-4052	110	5	review	review	NOUN
easat-4052	110	6	humans	human	NOUN
easat-4052	110	7	and	and	CCONJ
easat-4052	110	8	animals	animal	NOUN
easat-4052	110	9	with	with	ADP
easat-4052	110	10	knee	knee	NOUN
easat-4052	110	11	oa	oa	X
easat-4052	110	12	(	(	PUNCT
easat-4052	110	13	naturally	naturally	ADV
easat-4052	110	14	occurred	occur	VERB
easat-4052	110	15	and	and	CCONJ
easat-4052	110	16	induced	induce	VERB
easat-4052	110	17	)	)	PUNCT
easat-4052	110	18	various	various	ADJ
easat-4052	110	19	(	(	PUNCT
easat-4052	110	20	mostly	mostly	ADV
easat-4052	110	21	autologous	autologous	ADJ
easat-4052	110	22	admscs	admscs	NOUN
easat-4052	110	23	)	)	PUNCT
easat-4052	110	24	fibrin	fibrin	NOUN
easat-4052	110	25	glue	glue	NOUN
easat-4052	110	26	scaffold	scaffold	NOUN
easat-4052	110	27	(	(	PUNCT
easat-4052	110	28	1	1	NUM
easat-4052	110	29	study	study	NOUN
easat-4052	110	30	)	)	PUNCT
easat-4052	110	31	admscs	admsc	NOUN
easat-4052	110	32	demonstrated	demonstrate	VERB
easat-4052	110	33	significant	significant	ADJ
easat-4052	110	34	chondrogenic	chondrogenic	ADJ
easat-4052	110	35	differentiation	differentiation	NOUN
easat-4052	110	36	,	,	PUNCT
easat-4052	110	37	cartilage	cartilage	NOUN
easat-4052	110	38	regeneration	regeneration	NOUN
easat-4052	110	39	,	,	PUNCT
easat-4052	110	40	and	and	CCONJ
easat-4052	110	41	seamless	seamless	ADJ
easat-4052	110	42	integration	integration	NOUN
easat-4052	110	43	with	with	ADP
easat-4052	110	44	adjacent	adjacent	ADJ
easat-4052	110	45	tissues	tissue	NOUN
easat-4052	110	46	,	,	PUNCT
easat-4052	110	47	particularly	particularly	ADV
easat-4052	110	48	when	when	SCONJ
easat-4052	110	49	employed	employ	VERB
easat-4052	110	50	with	with	ADP
easat-4052	110	51	appropriate	appropriate	ADJ
easat-4052	110	52	scaffolds	scaffold	NOUN
easat-4052	110	53	or	or	CCONJ
easat-4052	110	54	within	within	ADP
easat-4052	110	55	cell	cell	NOUN
easat-4052	110	56	-	-	PUNCT
easat-4052	110	57	based	base	VERB
easat-4052	110	58	therapeutic	therapeutic	ADJ
easat-4052	110	59	approaches	approach	NOUN
easat-4052	110	60	.	.	PUNCT
easat-4052	111	1	meng	meng	PROPN
easat-4052	111	2	et	et	PROPN
easat-4052	111	3	al	al	PROPN
easat-4052	111	4	.	.	PROPN
easat-4052	111	5	,	,	PUNCT
easat-4052	111	6	2021	2021	NUM
easat-4052	111	7	[	[	X
easat-4052	111	8	18	18	NUM
easat-4052	111	9	]	]	X
easat-4052	111	10	systematic	systematic	ADJ
easat-4052	111	11	review	review	NOUN
easat-4052	111	12	and	and	CCONJ
easat-4052	111	13	meta	meta	ADJ
easat-4052	111	14	-	-	PUNCT
easat-4052	111	15	analysis	analysis	NOUN
easat-4052	111	16	humans	human	NOUN
easat-4052	111	17	with	with	ADP
easat-4052	111	18	present	present	ADJ
easat-4052	111	19	complaints	complaint	NOUN
easat-4052	111	20	and/or	and/or	CCONJ
easat-4052	111	21	a	a	DET
easat-4052	111	22	history	history	NOUN
easat-4052	111	23	of	of	ADP
easat-4052	111	24	cartilage	cartilage	NOUN
easat-4052	111	25	damage	damage	NOUN
easat-4052	111	26	various	various	ADJ
easat-4052	111	27	(	(	PUNCT
easat-4052	111	28	mostly	mostly	ADV
easat-4052	111	29	autologous	autologous	ADJ
easat-4052	111	30	abdominal	abdominal	ADJ
easat-4052	111	31	admscs	admscs	NOUN
easat-4052	111	32	fibrin	fibrin	NOUN
easat-4052	111	33	glue	glue	NOUN
easat-4052	111	34	scaffold	scaffold	NOUN
easat-4052	111	35	(	(	PUNCT
easat-4052	111	36	1	1	NUM
easat-4052	111	37	study	study	NOUN
easat-4052	111	38	)	)	PUNCT
easat-4052	111	39	the	the	DET
easat-4052	111	40	studies	study	NOUN
easat-4052	111	41	demonstrated	demonstrate	VERB
easat-4052	111	42	the	the	DET
easat-4052	111	43	safety	safety	NOUN
easat-4052	111	44	and	and	CCONJ
easat-4052	111	45	efficacy	efficacy	NOUN
easat-4052	111	46	of	of	ADP
easat-4052	111	47	admscs	admscs	NOUN
easat-4052	111	48	in	in	ADP
easat-4052	111	49	treating	treat	VERB
easat-4052	111	50	cartilage	cartilage	NOUN
easat-4052	111	51	defects	defect	NOUN
easat-4052	111	52	song	song	NOUN
easat-4052	111	53	et	et	PROPN
easat-4052	111	54	al	al	PROPN
easat-4052	111	55	.	.	PROPN
easat-4052	111	56	,	,	PUNCT
easat-4052	111	57	2016	2016	NUM
easat-4052	111	58	[	[	X
easat-4052	111	59	19	19	NUM
easat-4052	111	60	]	]	X
easat-4052	111	61	experimental	experimental	ADJ
easat-4052	111	62	research	research	NOUN
easat-4052	111	63	a	a	DET
easat-4052	111	64	49	49	NUM
easat-4052	111	65	-	-	PUNCT
easat-4052	111	66	year	year	NOUN
easat-4052	111	67	-	-	PUNCT
easat-4052	111	68	old	old	ADJ
easat-4052	111	69	female	female	NOUN
easat-4052	111	70	with	with	ADP
easat-4052	111	71	an	an	DET
easat-4052	111	72	osteochondral	osteochondral	ADJ
easat-4052	111	73	defect	defect	NOUN
easat-4052	111	74	(	(	PUNCT
easat-4052	111	75	not	not	PART
easat-4052	111	76	specified	specify	VERB
easat-4052	111	77	otherwise	otherwise	ADV
easat-4052	111	78	)	)	PUNCT
easat-4052	111	79	autologous	autologous	ADJ
easat-4052	111	80	admsc	admsc	NOUN
easat-4052	111	81	cancellous	cancellous	ADJ
easat-4052	111	82	and	and	CCONJ
easat-4052	111	83	hydrogel	hydrogel	NOUN
easat-4052	111	84	scaffolds	scaffold	NOUN
easat-4052	111	85	produced	produce	VERB
easat-4052	111	86	by	by	ADP
easat-4052	111	87	blending	blend	VERB
easat-4052	111	88	and	and	CCONJ
easat-4052	111	89	cross	cross	ADJ
easat-4052	111	90	-	-	ADJ
easat-4052	111	91	linking	link	VERB
easat-4052	111	92	chitosan	chitosan	NOUN
easat-4052	111	93	and	and	CCONJ
easat-4052	111	94	gelatin	gelatin	NOUN
easat-4052	111	95	admscs	admscs	NOUN
easat-4052	111	96	are	be	AUX
easat-4052	111	97	an	an	DET
easat-4052	111	98	ideal	ideal	ADJ
easat-4052	111	99	cell	cell	NOUN
easat-4052	111	100	source	source	NOUN
easat-4052	111	101	for	for	ADP
easat-4052	111	102	osteochondral	osteochondral	ADJ
easat-4052	111	103	composite	composite	ADJ
easat-4052	111	104	reconstruction	reconstruction	NOUN
easat-4052	111	105	.	.	PUNCT
easat-4052	112	1	additionally	additionally	ADV
easat-4052	112	2	,	,	PUNCT
easat-4052	112	3	the	the	DET
easat-4052	112	4	bilayered	bilayere	VERB
easat-4052	112	5	scaffold	scaffold	NOUN
easat-4052	112	6	significantly	significantly	ADV
easat-4052	112	7	boosted	boost	VERB
easat-4052	112	8	cell	cell	NOUN
easat-4052	112	9	proliferation	proliferation	NOUN
easat-4052	112	10	when	when	SCONJ
easat-4052	112	11	compared	compare	VERB
easat-4052	112	12	to	to	ADP
easat-4052	112	13	cells	cell	NOUN
easat-4052	112	14	seeded	seed	VERB
easat-4052	112	15	on	on	ADP
easat-4052	112	16	individual	individual	ADJ
easat-4052	112	17	scaffolds	scaffold	NOUN
easat-4052	112	18	.	.	PUNCT
easat-4052	113	1	zhang	zhang	PROPN
easat-4052	113	2	et	et	PROPN
easat-4052	113	3	al	al	PROPN
easat-4052	113	4	.	.	PROPN
easat-4052	113	5	,	,	PUNCT
easat-4052	113	6	2016	2016	NUM
easat-4052	113	7	[	[	X
easat-4052	113	8	20	20	NUM
easat-4052	113	9	]	]	X
easat-4052	113	10	experimental	experimental	ADJ
easat-4052	113	11	research	research	NOUN
easat-4052	113	12	animal	animal	NOUN
easat-4052	113	13	(	(	PUNCT
easat-4052	113	14	rabbit	rabbit	NOUN
easat-4052	113	15	)	)	PUNCT
easat-4052	113	16	with	with	ADP
easat-4052	113	17	osteochondral	osteochondral	ADJ
easat-4052	113	18	defect	defect	VERB
easat-4052	113	19	autologous	autologous	ADJ
easat-4052	113	20	admsc	admsc	NOUN
easat-4052	113	21	plga	plga	NOUN
easat-4052	113	22	/	/	SYM
easat-4052	113	23	chitosan	chitosan	NOUN
easat-4052	113	24	-	-	PUNCT
easat-4052	113	25	based	base	VERB
easat-4052	113	26	bilayer	bilayer	NOUN
easat-4052	113	27	scaffold	scaffold	NOUN
easat-4052	113	28	admscs	admsc	NOUN
easat-4052	113	29	spontaneously	spontaneously	ADV
easat-4052	113	30	aggregated	aggregate	VERB
easat-4052	113	31	to	to	PART
easat-4052	113	32	form	form	VERB
easat-4052	113	33	spheroids	spheroid	NOUN
easat-4052	113	34	in	in	ADP
easat-4052	113	35	situ	situ	NOUN
easat-4052	113	36	within	within	ADP
easat-4052	113	37	the	the	DET
easat-4052	113	38	chemically	chemically	ADV
easat-4052	113	39	cross	cross	ADJ
easat-4052	113	40	-	-	ADJ
easat-4052	113	41	linked	link	VERB
easat-4052	113	42	plga	plga	NOUN
easat-4052	113	43	/	/	SYM
easat-4052	113	44	chitosan	chitosan	ADJ
easat-4052	113	45	chondrogenic	chondrogenic	ADJ
easat-4052	113	46	scaffold	scaffold	NOUN
easat-4052	113	47	.	.	PUNCT
easat-4052	114	1	this	this	DET
easat-4052	114	2	process	process	NOUN
easat-4052	114	3	enhanced	enhance	VERB
easat-4052	114	4	both	both	CCONJ
easat-4052	114	5	the	the	DET
easat-4052	114	6	in	in	X
easat-4052	114	7	vitro	vitro	X
easat-4052	114	8	chondrogenic	chondrogenic	ADJ
easat-4052	114	9	differentiation	differentiation	NOUN
easat-4052	114	10	of	of	ADP
easat-4052	114	11	adsmcs	adsmcs	PROPN
easat-4052	114	12	and	and	CCONJ
easat-4052	114	13	the	the	PRON
easat-4052	114	14	in	in	ADP
easat-4052	114	15	vivo	vivo	ADJ
easat-4052	114	16	regeneration	regeneration	NOUN
easat-4052	114	17	of	of	ADP
easat-4052	114	18	hyaline	hyaline	NOUN
easat-4052	114	19	-	-	PUNCT
easat-4052	114	20	like	like	ADJ
easat-4052	114	21	cartilage	cartilage	NOUN
easat-4052	114	22	.	.	PUNCT
easat-4052	115	1	nordberg	nordberg	PROPN
easat-4052	115	2	et	et	PROPN
easat-4052	115	3	al	al	PROPN
easat-4052	115	4	.	.	PROPN
easat-4052	115	5	,	,	PUNCT
easat-4052	115	6	2021	2021	NUM
easat-4052	115	7	[	[	X
easat-4052	115	8	21	21	NUM
easat-4052	115	9	]	]	X
easat-4052	115	10	experimental	experimental	ADJ
easat-4052	115	11	research	research	NOUN
easat-4052	115	12	animal	animal	NOUN
easat-4052	115	13	(	(	PUNCT
easat-4052	115	14	minipig	minipig	PROPN
easat-4052	115	15	)	)	PUNCT
easat-4052	115	16	with	with	ADP
easat-4052	115	17	osteochondral	osteochondral	ADJ
easat-4052	115	18	defect	defect	VERB
easat-4052	115	19	autologous	autologous	ADJ
easat-4052	115	20	admsc	admsc	NOUN
easat-4052	115	21	3d	3d	ADV
easat-4052	115	22	-	-	PUNCT
easat-4052	115	23	bioplotted	bioplotte	VERB
easat-4052	115	24	scaffold	scaffold	NOUN
easat-4052	115	25	lesions	lesion	NOUN
easat-4052	115	26	treated	treat	VERB
easat-4052	115	27	with	with	ADP
easat-4052	115	28	scaffolds	scaffold	NOUN
easat-4052	115	29	demonstrated	demonstrate	VERB
easat-4052	115	30	enhanced	enhanced	ADJ
easat-4052	115	31	structural	structural	ADJ
easat-4052	115	32	organization	organization	NOUN
easat-4052	115	33	and	and	CCONJ
easat-4052	115	34	more	more	ADV
easat-4052	115	35	complete	complete	ADJ
easat-4052	115	36	tissue	tissue	NOUN
easat-4052	115	37	filling	filling	NOUN
easat-4052	115	38	compared	compare	VERB
easat-4052	115	39	to	to	ADP
easat-4052	115	40	untreated	untreated	ADJ
easat-4052	115	41	open	open	ADJ
easat-4052	115	42	lesions	lesion	NOUN
easat-4052	115	43	,	,	PUNCT
easat-4052	115	44	highlighting	highlight	VERB
easat-4052	115	45	the	the	DET
easat-4052	115	46	benefits	benefit	NOUN
easat-4052	115	47	of	of	ADP
easat-4052	115	48	scaffold	scaffold	NOUN
easat-4052	115	49	-	-	PUNCT
easat-4052	115	50	based	base	VERB
easat-4052	115	51	implants	implant	NOUN
easat-4052	115	52	in	in	ADP
easat-4052	115	53	tissue	tissue	NOUN
easat-4052	115	54	repair	repair	NOUN
easat-4052	115	55	.	.	PUNCT
easat-4052	116	1	zhong	zhong	PROPN
easat-4052	116	2	et	et	PROPN
easat-4052	116	3	al	al	PROPN
easat-4052	116	4	.	.	PROPN
easat-4052	116	5	,	,	PUNCT
easat-4052	116	6	2021	2021	NUM
easat-4052	116	7	[	[	X
easat-4052	116	8	22	22	NUM
easat-4052	116	9	]	]	X
easat-4052	116	10	experimental	experimental	ADJ
easat-4052	116	11	research	research	NOUN
easat-4052	116	12	animal	animal	NOUN
easat-4052	116	13	(	(	PUNCT
easat-4052	116	14	dog	dog	NOUN
easat-4052	116	15	)	)	PUNCT
easat-4052	116	16	with	with	ADP
easat-4052	116	17	osteochondral	osteochondral	ADJ
easat-4052	116	18	defect	defect	VERB
easat-4052	116	19	human	human	ADJ
easat-4052	116	20	umbilical	umbilical	ADJ
easat-4052	116	21	cord	cord	NOUN
easat-4052	116	22	blood	blood	NOUN
easat-4052	116	23	msc	msc	PROPN
easat-4052	116	24	bilayer	bilayer	PROPN
easat-4052	116	25	scaffolds	scaffold	NOUN
easat-4052	116	26	consisting	consist	VERB
easat-4052	116	27	of	of	ADP
easat-4052	116	28	hyaluronic	hyaluronic	NOUN
easat-4052	116	29	these	these	DET
easat-4052	116	30	scaffolds	scaffold	NOUN
easat-4052	116	31	effectively	effectively	ADV
easat-4052	116	32	repaired	repair	VERB
easat-4052	116	33	the	the	DET
easat-4052	116	34	defects	defect	NOUN
easat-4052	116	35	by	by	ADP
easat-4052	116	36	promoting	promote	VERB
easat-4052	116	37	the	the	DET
easat-4052	116	38	formation	formation	NOUN
easat-4052	116	39	of	of	ADP
easat-4052	116	40	9597	9597	NUM
easat-4052	116	41	edelweiss	edelweiss	PROPN
easat-4052	116	42	applied	apply	VERB
easat-4052	116	43	science	science	NOUN
easat-4052	116	44	and	and	CCONJ
easat-4052	116	45	technology	technology	NOUN
easat-4052	116	46	issn	issn	PROPN
easat-4052	116	47	:	:	PUNCT
easat-4052	116	48	2576	2576	NUM
easat-4052	116	49	-	-	SYM
easat-4052	116	50	8484	8484	NUM
easat-4052	116	51	vol	vol	NOUN
easat-4052	116	52	.	.	PROPN
easat-4052	116	53	8	8	NUM
easat-4052	116	54	,	,	PUNCT
easat-4052	116	55	no	no	INTJ
easat-4052	116	56	.	.	NOUN
easat-4052	116	57	6	6	NUM
easat-4052	116	58	:	:	SYM
easat-4052	116	59	9592	9592	NUM
easat-4052	116	60	-	-	SYM
easat-4052	116	61	9604	9604	NUM
easat-4052	116	62	,	,	PUNCT
easat-4052	116	63	2024	2024	NUM
easat-4052	116	64	doi	doi	NOUN
easat-4052	116	65	:	:	PUNCT
easat-4052	116	66	10.55214/25768484.v8i6.4052	10.55214/25768484.v8i6.4052	NUM
easat-4052	116	67	©	©	ADP
easat-4052	116	68	2024	2024	NUM
easat-4052	116	69	by	by	ADP
easat-4052	116	70	the	the	DET
easat-4052	116	71	authors	author	NOUN
easat-4052	116	72	;	;	PUNCT
easat-4052	116	73	licensee	licensee	PROPN
easat-4052	116	74	learning	learn	VERB
easat-4052	116	75	gate	gate	NOUN
easat-4052	116	76	acid	acid	PROPN
easat-4052	116	77	and	and	CCONJ
easat-4052	116	78	gelatin	gelatin	NOUN
easat-4052	116	79	-	-	PUNCT
easat-4052	116	80	based	base	VERB
easat-4052	116	81	microcrystals	microcrystal	NOUN
easat-4052	116	82	new	new	ADJ
easat-4052	116	83	tissue	tissue	NOUN
easat-4052	116	84	,	,	PUNCT
easat-4052	116	85	resulting	result	VERB
easat-4052	116	86	in	in	ADP
easat-4052	116	87	a	a	DET
easat-4052	116	88	biphasic	biphasic	ADJ
easat-4052	116	89	structure	structure	NOUN
easat-4052	116	90	comprising	comprise	VERB
easat-4052	116	91	both	both	CCONJ
easat-4052	116	92	bone	bone	NOUN
easat-4052	116	93	and	and	CCONJ
easat-4052	116	94	cartilage	cartilage	NOUN
easat-4052	116	95	.	.	PUNCT
easat-4052	117	1	ow	ow	INTJ
easat-4052	117	2	et	et	PROPN
easat-4052	117	3	al	al	PROPN
easat-4052	117	4	.	.	PROPN
easat-4052	117	5	,	,	PUNCT
easat-4052	117	6	2023	2023	NUM
easat-4052	117	7	[	[	X
easat-4052	117	8	23	23	NUM
easat-4052	117	9	]	]	X
easat-4052	117	10	meta	meta	ADJ
easat-4052	117	11	-	-	PUNCT
easat-4052	117	12	analysis	analysis	NOUN
easat-4052	117	13	humans	human	NOUN
easat-4052	117	14	with	with	ADP
easat-4052	117	15	highgrade	highgrade	NOUN
easat-4052	117	16	chondral	chondral	ADJ
easat-4052	117	17	lesions	lesion	NOUN
easat-4052	117	18	on	on	ADP
easat-4052	117	19	the	the	DET
easat-4052	117	20	tibiofemoral	tibiofemoral	ADJ
easat-4052	117	21	or	or	CCONJ
easat-4052	117	22	patellofemoral	patellofemoral	ADJ
easat-4052	117	23	articular	articular	ADJ
easat-4052	117	24	surfaces	surface	NOUN
easat-4052	117	25	autologous	autologous	ADJ
easat-4052	117	26	admsc	admsc	NOUN
easat-4052	117	27	bioscaffold	bioscaffold	NOUN
easat-4052	117	28	and	and	CCONJ
easat-4052	117	29	acellular	acellular	ADJ
easat-4052	117	30	scaffold	scaffold	NOUN
easat-4052	117	31	with	with	ADP
easat-4052	117	32	cbma	cbma	PROPN
easat-4052	117	33	augmentation	augmentation	NOUN
easat-4052	117	34	cartilage	cartilage	NOUN
easat-4052	117	35	repair	repair	NOUN
easat-4052	117	36	using	use	VERB
easat-4052	117	37	admsc	admsc	NOUN
easat-4052	117	38	with	with	ADP
easat-4052	117	39	cbma	cbma	PROPN
easat-4052	117	40	augmentation	augmentation	NOUN
easat-4052	117	41	shows	show	VERB
easat-4052	117	42	slightly	slightly	ADV
easat-4052	117	43	superior	superior	ADJ
easat-4052	117	44	short	short	ADJ
easat-4052	117	45	-	-	PUNCT
easat-4052	117	46	term	term	NOUN
easat-4052	117	47	outcomes	outcome	NOUN
easat-4052	117	48	compared	compare	VERB
easat-4052	117	49	to	to	ADP
easat-4052	117	50	scaffold	scaffold	NOUN
easat-4052	117	51	-	-	PUNCT
easat-4052	117	52	implanted	implant	VERB
easat-4052	117	53	mscs	msc	NOUN
easat-4052	117	54	.	.	PUNCT
easat-4052	118	1	source	source	NOUN
easat-4052	118	2	:	:	PUNCT
easat-4052	118	3	admscs	admsc	NOUN
easat-4052	118	4	,	,	PUNCT
easat-4052	118	5	adipose	adipose	NOUN
easat-4052	118	6	-	-	PUNCT
easat-4052	118	7	derived	derive	VERB
easat-4052	118	8	mesenchymal	mesenchymal	NOUN
easat-4052	118	9	stem	stem	NOUN
easat-4052	118	10	cells	cell	NOUN
easat-4052	118	11	;	;	PUNCT
easat-4052	118	12	msc	msc	NOUN
easat-4052	118	13	,	,	PUNCT
easat-4052	118	14	mesenchymal	mesenchymal	ADJ
easat-4052	118	15	stem	stem	NOUN
easat-4052	118	16	cells	cell	NOUN
easat-4052	118	17	;	;	PUNCT
easat-4052	118	18	oa	oa	INTJ
easat-4052	118	19	,	,	PUNCT
easat-4052	118	20	osteoarthritis	osteoarthritis	NOUN
easat-4052	118	21	;	;	PUNCT
easat-4052	118	22	plga	plga	NOUN
easat-4052	118	23	,	,	PUNCT
easat-4052	118	24	poly(l	poly(l	ADJ
easat-4052	118	25	-	-	ADJ
easat-4052	118	26	glutamic	glutamic	ADJ
easat-4052	118	27	acid	acid	NOUN
easat-4052	118	28	)	)	PUNCT
easat-4052	118	29	;	;	PUNCT
easat-4052	118	30	cbma	cbma	PROPN
easat-4052	118	31	,	,	PUNCT
easat-4052	118	32	concentrated	concentrated	ADJ
easat-4052	118	33	bone	bone	NOUN
easat-4052	118	34	marrow	marrow	NOUN
easat-4052	118	35	aspirate	aspirate	NOUN
easat-4052	118	36	.	.	PUNCT
easat-4052	119	1	9598	9598	NUM
easat-4052	119	2	edelweiss	edelweiss	PROPN
easat-4052	119	3	applied	apply	VERB
easat-4052	119	4	science	science	NOUN
easat-4052	119	5	and	and	CCONJ
easat-4052	119	6	technology	technology	NOUN
easat-4052	119	7	issn	issn	PROPN
easat-4052	119	8	:	:	PUNCT
easat-4052	119	9	2576	2576	NUM
easat-4052	119	10	-	-	SYM
easat-4052	119	11	8484	8484	NUM
easat-4052	119	12	vol	vol	NOUN
easat-4052	119	13	.	.	PROPN
easat-4052	119	14	8	8	NUM
easat-4052	119	15	,	,	PUNCT
easat-4052	119	16	no	no	INTJ
easat-4052	119	17	.	.	NOUN
easat-4052	120	1	6	6	NUM
easat-4052	120	2	:	:	SYM
easat-4052	120	3	9592	9592	NUM
easat-4052	120	4	-	-	SYM
easat-4052	120	5	9604	9604	NUM
easat-4052	120	6	,	,	PUNCT
easat-4052	120	7	2024	2024	NUM
easat-4052	120	8	doi	doi	NOUN
easat-4052	120	9	:	:	PUNCT
easat-4052	120	10	10.55214/25768484.v8i6.4052	10.55214/25768484.v8i6.4052	NUM
easat-4052	121	1	©	©	ADP
easat-4052	121	2	2024	2024	NUM
easat-4052	121	3	by	by	ADP
easat-4052	121	4	the	the	DET
easat-4052	121	5	authors	author	NOUN
easat-4052	121	6	;	;	PUNCT
easat-4052	121	7	licensee	licensee	PROPN
easat-4052	121	8	learning	learning	NOUN
easat-4052	121	9	gate	gate	NOUN
easat-4052	121	10	4	4	NUM
easat-4052	121	11	.	.	PUNCT
easat-4052	121	12	discussion	discussion	NOUN
easat-4052	121	13	the	the	DET
easat-4052	121	14	results	result	NOUN
easat-4052	121	15	of	of	ADP
easat-4052	121	16	this	this	DET
easat-4052	121	17	literature	literature	NOUN
easat-4052	121	18	review	review	NOUN
easat-4052	121	19	emphasize	emphasize	VERB
easat-4052	121	20	the	the	DET
easat-4052	121	21	potential	potential	NOUN
easat-4052	121	22	of	of	ADP
easat-4052	121	23	combining	combine	VERB
easat-4052	121	24	scaffolds	scaffold	NOUN
easat-4052	121	25	with	with	ADP
easat-4052	121	26	admscs	admscs	NOUN
easat-4052	121	27	to	to	ADP
easat-4052	121	28	regenerate	regenerate	VERB
easat-4052	121	29	knee	knee	NOUN
easat-4052	121	30	joint	joint	ADJ
easat-4052	121	31	cartilage	cartilage	NOUN
easat-4052	121	32	defects	defect	NOUN
easat-4052	121	33	.	.	PUNCT
easat-4052	122	1	both	both	DET
easat-4052	122	2	preclinical	preclinical	ADJ
easat-4052	122	3	and	and	CCONJ
easat-4052	122	4	clinical	clinical	ADJ
easat-4052	122	5	studies	study	NOUN
easat-4052	122	6	have	have	AUX
easat-4052	122	7	shown	show	VERB
easat-4052	122	8	that	that	SCONJ
easat-4052	122	9	scaffolds	scaffold	NOUN
easat-4052	122	10	,	,	PUNCT
easat-4052	122	11	when	when	SCONJ
easat-4052	122	12	seeded	seed	VERB
easat-4052	122	13	with	with	ADP
easat-4052	122	14	admscs	admsc	NOUN
easat-4052	122	15	,	,	PUNCT
easat-4052	122	16	play	play	VERB
easat-4052	122	17	a	a	DET
easat-4052	122	18	crucial	crucial	ADJ
easat-4052	122	19	role	role	NOUN
easat-4052	122	20	in	in	ADP
easat-4052	122	21	promoting	promote	VERB
easat-4052	122	22	chondrogenesis	chondrogenesis	NOUN
easat-4052	122	23	,	,	PUNCT
easat-4052	122	24	supporting	support	VERB
easat-4052	122	25	tissue	tissue	NOUN
easat-4052	122	26	integration	integration	NOUN
easat-4052	122	27	,	,	PUNCT
easat-4052	122	28	and	and	CCONJ
easat-4052	122	29	enhancing	enhance	VERB
easat-4052	122	30	cartilage	cartilage	NOUN
easat-4052	122	31	repair	repair	NOUN
easat-4052	122	32	.	.	PUNCT
easat-4052	123	1	this	this	DET
easat-4052	123	2	combination	combination	NOUN
easat-4052	123	3	offers	offer	VERB
easat-4052	123	4	a	a	DET
easat-4052	123	5	promising	promising	ADJ
easat-4052	123	6	therapeutic	therapeutic	ADJ
easat-4052	123	7	approach	approach	NOUN
easat-4052	123	8	for	for	ADP
easat-4052	123	9	addressing	address	VERB
easat-4052	123	10	cartilage	cartilage	NOUN
easat-4052	123	11	damage	damage	NOUN
easat-4052	123	12	,	,	PUNCT
easat-4052	123	13	improving	improve	VERB
easat-4052	123	14	functional	functional	ADJ
easat-4052	123	15	recovery	recovery	NOUN
easat-4052	123	16	,	,	PUNCT
easat-4052	123	17	and	and	CCONJ
easat-4052	123	18	reducing	reduce	VERB
easat-4052	123	19	pain	pain	NOUN
easat-4052	123	20	.	.	PUNCT
easat-4052	124	1	in	in	ADP
easat-4052	124	2	this	this	DET
easat-4052	124	3	section	section	NOUN
easat-4052	124	4	,	,	PUNCT
easat-4052	124	5	a	a	DET
easat-4052	124	6	review	review	NOUN
easat-4052	124	7	will	will	AUX
easat-4052	124	8	be	be	AUX
easat-4052	124	9	made	make	VERB
easat-4052	124	10	regarding	regard	VERB
easat-4052	124	11	admscs	admscs	NOUN
easat-4052	124	12	and	and	CCONJ
easat-4052	124	13	scaffolds	scaffold	NOUN
easat-4052	124	14	in	in	ADP
easat-4052	124	15	general	general	ADJ
easat-4052	124	16	.	.	PUNCT
easat-4052	125	1	4.1	4.1	NUM
easat-4052	125	2	.	.	PUNCT
easat-4052	125	3	properties	property	NOUN
easat-4052	125	4	of	of	ADP
easat-4052	125	5	admsc	admsc	NOUN
easat-4052	125	6	all	all	DET
easat-4052	125	7	mammalian	mammalian	ADJ
easat-4052	125	8	species	specie	NOUN
easat-4052	125	9	and	and	CCONJ
easat-4052	125	10	certain	certain	ADJ
easat-4052	125	11	non	non	ADJ
easat-4052	125	12	-	-	ADJ
easat-4052	125	13	mammalian	mammalian	ADJ
easat-4052	125	14	species	specie	NOUN
easat-4052	125	15	contain	contain	VERB
easat-4052	125	16	adipose	adipose	ADP
easat-4052	125	17	tissue	tissue	NOUN
easat-4052	125	18	,	,	PUNCT
easat-4052	125	19	a	a	DET
easat-4052	125	20	complex	complex	ADJ
easat-4052	125	21	organ	organ	NOUN
easat-4052	125	22	with	with	ADP
easat-4052	125	23	endocrine	endocrine	NOUN
easat-4052	125	24	,	,	PUNCT
easat-4052	125	25	immunomodulatory	immunomodulatory	NOUN
easat-4052	125	26	,	,	PUNCT
easat-4052	125	27	energy	energy	NOUN
easat-4052	125	28	-	-	PUNCT
easat-4052	125	29	storage	storage	NOUN
easat-4052	125	30	,	,	PUNCT
easat-4052	125	31	and	and	CCONJ
easat-4052	125	32	structural	structural	ADJ
easat-4052	125	33	roles	role	NOUN
easat-4052	125	34	[	[	X
easat-4052	125	35	26	26	NUM
easat-4052	125	36	]	]	PUNCT
easat-4052	125	37	.	.	PUNCT
easat-4052	126	1	its	its	PRON
easat-4052	126	2	diverse	diverse	ADJ
easat-4052	126	3	cell	cell	NOUN
easat-4052	126	4	population	population	NOUN
easat-4052	126	5	includes	include	VERB
easat-4052	126	6	mature	mature	ADJ
easat-4052	126	7	adipocytes	adipocyte	NOUN
easat-4052	126	8	(	(	PUNCT
easat-4052	126	9	more	more	ADJ
easat-4052	126	10	than	than	ADP
easat-4052	126	11	90	90	NUM
easat-4052	126	12	%	%	NOUN
easat-4052	126	13	)	)	PUNCT
easat-4052	126	14	and	and	CCONJ
easat-4052	126	15	svf	svf	PROPN
easat-4052	126	16	,	,	PUNCT
easat-4052	126	17	which	which	PRON
easat-4052	126	18	is	be	AUX
easat-4052	126	19	composed	compose	VERB
easat-4052	126	20	of	of	ADP
easat-4052	126	21	hematopoietic	hematopoietic	ADJ
easat-4052	126	22	cells	cell	NOUN
easat-4052	126	23	like	like	ADP
easat-4052	126	24	granulocytes	granulocyte	NOUN
easat-4052	126	25	,	,	PUNCT
easat-4052	126	26	monocytes	monocyte	NOUN
easat-4052	126	27	,	,	PUNCT
easat-4052	126	28	and	and	CCONJ
easat-4052	126	29	lymphocytes	lymphocyte	NOUN
easat-4052	126	30	(	(	PUNCT
easat-4052	126	31	25–45	25–45	NUM
easat-4052	126	32	%	%	NOUN
easat-4052	126	33	)	)	PUNCT
easat-4052	126	34	,	,	PUNCT
easat-4052	126	35	stromal	stromal	ADJ
easat-4052	126	36	/	/	SYM
easat-4052	126	37	stem	stem	NOUN
easat-4052	126	38	cells	cell	NOUN
easat-4052	126	39	(	(	PUNCT
easat-4052	126	40	15–30	15–30	NUM
easat-4052	126	41	%	%	NOUN
easat-4052	126	42	)	)	PUNCT
easat-4052	126	43	,	,	PUNCT
easat-4052	126	44	endothelial	endothelial	NOUN
easat-4052	126	45	cells	cell	NOUN
easat-4052	126	46	(	(	PUNCT
easat-4052	126	47	10–20	10–20	NUM
easat-4052	126	48	%	%	NOUN
easat-4052	126	49	)	)	PUNCT
easat-4052	126	50	,	,	PUNCT
easat-4052	126	51	and	and	CCONJ
easat-4052	126	52	pericytes	pericyte	NOUN
easat-4052	126	53	(	(	PUNCT
easat-4052	126	54	3–5	3–5	NUM
easat-4052	126	55	%	%	NOUN
easat-4052	126	56	)	)	PUNCT
easat-4052	127	1	[	[	X
easat-4052	127	2	11,26	11,26	NOUN
easat-4052	127	3	]	]	PUNCT
easat-4052	127	4	.	.	PUNCT
easat-4052	128	1	age	age	NOUN
easat-4052	128	2	,	,	PUNCT
easat-4052	128	3	anatomical	anatomical	ADJ
easat-4052	128	4	location	location	NOUN
easat-4052	128	5	,	,	PUNCT
easat-4052	128	6	and	and	CCONJ
easat-4052	128	7	histological	histological	ADJ
easat-4052	128	8	type	type	NOUN
easat-4052	128	9	are	be	AUX
easat-4052	128	10	some	some	DET
easat-4052	128	11	variables	variable	NOUN
easat-4052	128	12	that	that	PRON
easat-4052	128	13	affect	affect	VERB
easat-4052	128	14	the	the	DET
easat-4052	128	15	percentage	percentage	NOUN
easat-4052	128	16	of	of	ADP
easat-4052	128	17	stem	stem	NOUN
easat-4052	128	18	cells	cell	NOUN
easat-4052	128	19	in	in	ADP
easat-4052	128	20	adipose	adipose	ADJ
easat-4052	128	21	tissue	tissue	NOUN
easat-4052	128	22	.	.	PUNCT
easat-4052	129	1	brown	brown	ADJ
easat-4052	129	2	adipose	adipose	ADJ
easat-4052	129	3	tissue	tissue	NOUN
easat-4052	129	4	,	,	PUNCT
easat-4052	129	5	which	which	PRON
easat-4052	129	6	is	be	AUX
easat-4052	129	7	characterized	characterize	VERB
easat-4052	129	8	by	by	ADP
easat-4052	129	9	its	its	PRON
easat-4052	129	10	high	high	ADJ
easat-4052	129	11	mitochondrial	mitochondrial	ADJ
easat-4052	129	12	content	content	NOUN
easat-4052	129	13	,	,	PUNCT
easat-4052	129	14	is	be	AUX
easat-4052	129	15	specialized	specialize	VERB
easat-4052	129	16	for	for	ADP
easat-4052	129	17	thermogenesis	thermogenesis	NOUN
easat-4052	129	18	,	,	PUNCT
easat-4052	129	19	while	while	SCONJ
easat-4052	129	20	white	white	ADJ
easat-4052	129	21	adipose	adipose	ADJ
easat-4052	129	22	tissue	tissue	NOUN
easat-4052	129	23	,	,	PUNCT
easat-4052	129	24	which	which	PRON
easat-4052	129	25	is	be	AUX
easat-4052	129	26	more	more	ADV
easat-4052	129	27	prevalent	prevalent	ADJ
easat-4052	129	28	,	,	PUNCT
easat-4052	129	29	primarily	primarily	ADV
easat-4052	129	30	serves	serve	VERB
easat-4052	129	31	in	in	ADP
easat-4052	129	32	energy	energy	NOUN
easat-4052	129	33	storage	storage	NOUN
easat-4052	129	34	and	and	CCONJ
easat-4052	129	35	organ	organ	NOUN
easat-4052	129	36	protection	protection	NOUN
easat-4052	130	1	[	[	X
easat-4052	130	2	11	11	NUM
easat-4052	130	3	]	]	PUNCT
easat-4052	130	4	.	.	PUNCT
easat-4052	131	1	multilineage	multilineage	PROPN
easat-4052	131	2	admscs	admsc	NOUN
easat-4052	131	3	are	be	AUX
easat-4052	131	4	found	find	VERB
easat-4052	131	5	predominantly	predominantly	ADV
easat-4052	131	6	in	in	ADP
easat-4052	131	7	white	white	ADJ
easat-4052	131	8	adipose	adipose	ADP
easat-4052	131	9	tissue	tissue	NOUN
easat-4052	131	10	and	and	CCONJ
easat-4052	131	11	are	be	AUX
easat-4052	131	12	more	more	ADV
easat-4052	131	13	concentrated	concentrated	ADJ
easat-4052	131	14	in	in	ADP
easat-4052	131	15	subcutaneous	subcutaneous	ADJ
easat-4052	131	16	fat	fat	ADJ
easat-4052	131	17	deposits	deposit	NOUN
easat-4052	131	18	compared	compare	VERB
easat-4052	131	19	to	to	ADP
easat-4052	131	20	visceral	visceral	ADJ
easat-4052	131	21	fat	fat	ADJ
easat-4052	131	22	deposits	deposit	NOUN
easat-4052	131	23	[	[	X
easat-4052	131	24	26	26	NUM
easat-4052	131	25	]	]	PUNCT
easat-4052	131	26	.	.	PUNCT
easat-4052	132	1	admscs	admscs	PROPN
easat-4052	132	2	are	be	AUX
easat-4052	132	3	multipotent	multipotent	NOUN
easat-4052	132	4	stem	stem	NOUN
easat-4052	132	5	cells	cell	NOUN
easat-4052	132	6	characterized	characterize	VERB
easat-4052	132	7	by	by	ADP
easat-4052	132	8	an	an	DET
easat-4052	132	9	undifferentiated	undifferentiated	ADJ
easat-4052	132	10	immunophenotype	immunophenotype	NOUN
easat-4052	132	11	,	,	PUNCT
easat-4052	132	12	with	with	ADP
easat-4052	132	13	inherent	inherent	ADJ
easat-4052	132	14	capacities	capacity	NOUN
easat-4052	132	15	for	for	ADP
easat-4052	132	16	self	self	NOUN
easat-4052	132	17	-	-	PUNCT
easat-4052	132	18	renewal	renewal	NOUN
easat-4052	132	19	and	and	CCONJ
easat-4052	132	20	multipotency	multipotency	NOUN
easat-4052	132	21	[	[	X
easat-4052	132	22	11	11	NUM
easat-4052	132	23	]	]	PUNCT
easat-4052	132	24	.	.	PUNCT
easat-4052	133	1	these	these	DET
easat-4052	133	2	cells	cell	NOUN
easat-4052	133	3	can	can	AUX
easat-4052	133	4	differentiate	differentiate	VERB
easat-4052	133	5	into	into	ADP
easat-4052	133	6	various	various	ADJ
easat-4052	133	7	cell	cell	NOUN
easat-4052	133	8	types	type	NOUN
easat-4052	133	9	,	,	PUNCT
easat-4052	133	10	including	include	VERB
easat-4052	133	11	osteoblasts	osteoblast	NOUN
easat-4052	133	12	,	,	PUNCT
easat-4052	133	13	chondrocytes	chondrocyte	NOUN
easat-4052	133	14	,	,	PUNCT
easat-4052	133	15	neurons	neuron	NOUN
easat-4052	133	16	,	,	PUNCT
easat-4052	133	17	myocytes	myocyte	NOUN
easat-4052	133	18	,	,	PUNCT
easat-4052	133	19	endothelial	endothelial	ADJ
easat-4052	133	20	cells	cell	NOUN
easat-4052	133	21	,	,	PUNCT
easat-4052	133	22	adipocytes	adipocyte	NOUN
easat-4052	133	23	,	,	PUNCT
easat-4052	133	24	and	and	CCONJ
easat-4052	133	25	cardiomyocytes	cardiomyocyte	NOUN
easat-4052	133	26	[	[	X
easat-4052	133	27	11,26	11,26	NOUN
easat-4052	133	28	]	]	PUNCT
easat-4052	133	29	.	.	PUNCT
easat-4052	134	1	furthermore	furthermore	ADV
easat-4052	134	2	,	,	PUNCT
easat-4052	134	3	admscs	admsc	NOUN
easat-4052	134	4	respond	respond	VERB
easat-4052	134	5	to	to	ADP
easat-4052	134	6	inflammatory	inflammatory	ADJ
easat-4052	134	7	stimuli	stimulus	NOUN
easat-4052	134	8	by	by	ADP
easat-4052	134	9	secreting	secrete	VERB
easat-4052	134	10	antiinflammatory	antiinflammatory	NOUN
easat-4052	134	11	cytokines	cytokine	NOUN
easat-4052	134	12	,	,	PUNCT
easat-4052	134	13	such	such	ADJ
easat-4052	134	14	as	as	ADP
easat-4052	134	15	tumor	tumor	NOUN
easat-4052	134	16	necrosis	necrosis	NOUN
easat-4052	134	17	factor	factor	NOUN
easat-4052	134	18	-	-	PUNCT
easat-4052	134	19	α	α	X
easat-4052	134	20	(	(	PUNCT
easat-4052	134	21	tnf	tnf	PROPN
easat-4052	134	22	-	-	PUNCT
easat-4052	134	23	α	α	NOUN
easat-4052	134	24	)	)	PUNCT
easat-4052	134	25	,	,	PUNCT
easat-4052	134	26	interleukin-4	interleukin-4	PROPN
easat-4052	134	27	(	(	PUNCT
easat-4052	134	28	il-4	il-4	NUM
easat-4052	134	29	)	)	PUNCT
easat-4052	134	30	,	,	PUNCT
easat-4052	134	31	il-6	il-6	NOUN
easat-4052	134	32	,	,	PUNCT
easat-4052	134	33	il-10	il-10	PRON
easat-4052	134	34	,	,	PUNCT
easat-4052	134	35	and	and	CCONJ
easat-4052	134	36	il-1	il-1	ADP
easat-4052	134	37	receptor	receptor	NOUN
easat-4052	134	38	antagonists	antagonist	NOUN
easat-4052	134	39	.	.	PUNCT
easat-4052	135	1	additionally	additionally	ADV
easat-4052	135	2	,	,	PUNCT
easat-4052	135	3	they	they	PRON
easat-4052	135	4	produce	produce	VERB
easat-4052	135	5	numerous	numerous	ADJ
easat-4052	135	6	growth	growth	NOUN
easat-4052	135	7	factors	factor	NOUN
easat-4052	135	8	,	,	PUNCT
easat-4052	135	9	including	include	VERB
easat-4052	135	10	tgf	tgf	PROPN
easat-4052	135	11	-	-	PUNCT
easat-4052	135	12	β1	β1	PROPN
easat-4052	135	13	,	,	PUNCT
easat-4052	135	14	hepatocyte	hepatocyte	NOUN
easat-4052	135	15	growth	growth	NOUN
easat-4052	135	16	factor	factor	NOUN
easat-4052	135	17	(	(	PUNCT
easat-4052	135	18	hgf	hgf	PROPN
easat-4052	135	19	)	)	PUNCT
easat-4052	135	20	,	,	PUNCT
easat-4052	135	21	vascular	vascular	ADJ
easat-4052	135	22	endothelial	endothelial	ADJ
easat-4052	135	23	growth	growth	NOUN
easat-4052	135	24	factor	factor	NOUN
easat-4052	135	25	(	(	PUNCT
easat-4052	135	26	vegf	vegf	PROPN
easat-4052	135	27	)	)	PUNCT
easat-4052	135	28	,	,	PUNCT
easat-4052	135	29	and	and	CCONJ
easat-4052	135	30	stromal	stromal	ADJ
easat-4052	135	31	cell	cell	NOUN
easat-4052	135	32	-	-	PUNCT
easat-4052	135	33	derived	derive	VERB
easat-4052	135	34	factor-1	factor-1	NUM
easat-4052	135	35	(	(	PUNCT
easat-4052	135	36	sdf-1	sdf-1	NUM
easat-4052	135	37	)	)	PUNCT
easat-4052	135	38	,	,	PUNCT
easat-4052	135	39	which	which	PRON
easat-4052	135	40	play	play	VERB
easat-4052	135	41	pivotal	pivotal	ADJ
easat-4052	135	42	roles	role	NOUN
easat-4052	135	43	in	in	ADP
easat-4052	135	44	tissue	tissue	NOUN
easat-4052	135	45	remodeling	remodeling	NOUN
easat-4052	135	46	,	,	PUNCT
easat-4052	135	47	angiogenesis	angiogenesis	NOUN
easat-4052	135	48	,	,	PUNCT
easat-4052	135	49	and	and	CCONJ
easat-4052	135	50	anti	anti	ADJ
easat-4052	135	51	-	-	ADJ
easat-4052	135	52	apoptotic	apoptotic	ADJ
easat-4052	135	53	processes	process	NOUN
easat-4052	135	54	[	[	X
easat-4052	135	55	11,26–28	11,26–28	X
easat-4052	135	56	]	]	PUNCT
easat-4052	135	57	.	.	PUNCT
easat-4052	136	1	notably	notably	ADV
easat-4052	136	2	,	,	PUNCT
easat-4052	136	3	admscs	admsc	NOUN
easat-4052	136	4	also	also	ADV
easat-4052	136	5	exhibit	exhibit	VERB
easat-4052	136	6	immunomodulatory	immunomodulatory	ADJ
easat-4052	136	7	properties	property	NOUN
easat-4052	136	8	by	by	ADP
easat-4052	136	9	inhibiting	inhibit	VERB
easat-4052	136	10	the	the	DET
easat-4052	136	11	proliferation	proliferation	NOUN
easat-4052	136	12	and	and	CCONJ
easat-4052	136	13	function	function	NOUN
easat-4052	136	14	of	of	ADP
easat-4052	136	15	various	various	ADJ
easat-4052	136	16	immune	immune	ADJ
easat-4052	136	17	cells	cell	NOUN
easat-4052	136	18	,	,	PUNCT
easat-4052	136	19	such	such	ADJ
easat-4052	136	20	as	as	ADP
easat-4052	136	21	t	t	PROPN
easat-4052	136	22	cells	cell	NOUN
easat-4052	136	23	,	,	PUNCT
easat-4052	136	24	b	b	NOUN
easat-4052	136	25	cells	cell	NOUN
easat-4052	136	26	,	,	PUNCT
easat-4052	136	27	macrophages	macrophage	NOUN
easat-4052	136	28	,	,	PUNCT
easat-4052	136	29	monocytes	monocyte	NOUN
easat-4052	136	30	,	,	PUNCT
easat-4052	136	31	and	and	CCONJ
easat-4052	136	32	natural	natural	ADJ
easat-4052	136	33	killer	killer	NOUN
easat-4052	136	34	cells	cell	NOUN
easat-4052	136	35	[	[	X
easat-4052	136	36	26–28	26–28	NUM
easat-4052	136	37	]	]	PUNCT
easat-4052	136	38	.	.	PUNCT
easat-4052	137	1	4.2	4.2	NUM
easat-4052	137	2	.	.	PUNCT
easat-4052	137	3	harvesting	harvesting	NOUN
easat-4052	137	4	and	and	CCONJ
easat-4052	137	5	isolation	isolation	NOUN
easat-4052	137	6	technique	technique	NOUN
easat-4052	137	7	contemporary	contemporary	ADJ
easat-4052	137	8	approaches	approach	NOUN
easat-4052	137	9	to	to	ADP
easat-4052	137	10	harvesting	harvest	VERB
easat-4052	137	11	adipose	adipose	PRON
easat-4052	137	12	tissue	tissue	NOUN
easat-4052	137	13	include	include	VERB
easat-4052	137	14	using	use	VERB
easat-4052	137	15	syringes	syrinx	NOUN
easat-4052	137	16	,	,	PUNCT
easat-4052	137	17	liposuction	liposuction	NOUN
easat-4052	137	18	techniques	technique	NOUN
easat-4052	137	19	,	,	PUNCT
easat-4052	137	20	and	and	CCONJ
easat-4052	137	21	direct	direct	ADJ
easat-4052	137	22	excision	excision	NOUN
easat-4052	137	23	.	.	PUNCT
easat-4052	138	1	admscs	admscs	PROPN
easat-4052	138	2	intended	intend	VERB
easat-4052	138	3	for	for	ADP
easat-4052	138	4	experimental	experimental	ADJ
easat-4052	138	5	and	and	CCONJ
easat-4052	138	6	therapeutic	therapeutic	ADJ
easat-4052	138	7	applications	application	NOUN
easat-4052	138	8	can	can	AUX
easat-4052	138	9	be	be	AUX
easat-4052	138	10	isolated	isolate	VERB
easat-4052	138	11	from	from	ADP
easat-4052	138	12	subcutaneous	subcutaneous	ADJ
easat-4052	138	13	fat	fat	NOUN
easat-4052	138	14	in	in	ADP
easat-4052	138	15	the	the	DET
easat-4052	138	16	abdomen	abdomen	NOUN
easat-4052	138	17	,	,	PUNCT
easat-4052	138	18	thighs	thigh	NOUN
easat-4052	138	19	,	,	PUNCT
easat-4052	138	20	and	and	CCONJ
easat-4052	138	21	arms	arm	NOUN
easat-4052	139	1	[	[	X
easat-4052	139	2	25	25	NUM
easat-4052	139	3	]	]	PUNCT
easat-4052	139	4	.	.	PUNCT
easat-4052	140	1	the	the	DET
easat-4052	140	2	reviewed	review	VERB
easat-4052	140	3	studies	study	NOUN
easat-4052	140	4	isolated	isolate	VERB
easat-4052	140	5	admscs	admscs	NOUN
easat-4052	140	6	from	from	ADP
easat-4052	140	7	sources	source	NOUN
easat-4052	140	8	such	such	ADJ
easat-4052	140	9	as	as	ADP
easat-4052	140	10	gluteal	gluteal	NOUN
easat-4052	140	11	or	or	CCONJ
easat-4052	140	12	abdominal	abdominal	ADJ
easat-4052	140	13	adipose	adipose	ADJ
easat-4052	140	14	tissue	tissue	NOUN
easat-4052	140	15	and	and	CCONJ
easat-4052	140	16	the	the	DET
easat-4052	140	17	infrapatellar	infrapatellar	ADJ
easat-4052	140	18	fat	fat	ADJ
easat-4052	140	19	pad	pad	NOUN
easat-4052	140	20	(	(	PUNCT
easat-4052	140	21	ifpf	ifpf	NOUN
easat-4052	140	22	)	)	PUNCT
easat-4052	140	23	.	.	PUNCT
easat-4052	141	1	while	while	SCONJ
easat-4052	141	2	the	the	DET
easat-4052	141	3	optimal	optimal	ADJ
easat-4052	141	4	source	source	NOUN
easat-4052	141	5	for	for	ADP
easat-4052	141	6	admscs	admscs	NOUN
easat-4052	141	7	remains	remain	VERB
easat-4052	141	8	under	under	ADP
easat-4052	141	9	investigation	investigation	NOUN
easat-4052	141	10	,	,	PUNCT
easat-4052	141	11	ifpfs	ifpfs	PROPN
easat-4052	141	12	present	present	ADJ
easat-4052	141	13	a	a	DET
easat-4052	141	14	compelling	compelling	ADJ
easat-4052	141	15	option	option	NOUN
easat-4052	141	16	compared	compare	VERB
easat-4052	141	17	to	to	ADP
easat-4052	141	18	other	other	ADJ
easat-4052	141	19	adipose	adipose	ADJ
easat-4052	141	20	tissues	tissue	NOUN
easat-4052	141	21	.	.	PUNCT
easat-4052	142	1	this	this	PRON
easat-4052	142	2	is	be	AUX
easat-4052	142	3	largely	largely	ADV
easat-4052	142	4	because	because	SCONJ
easat-4052	142	5	ifpfs	ifpf	NOUN
easat-4052	142	6	are	be	AUX
easat-4052	142	7	often	often	ADV
easat-4052	142	8	collected	collect	VERB
easat-4052	142	9	during	during	ADP
easat-4052	142	10	the	the	DET
easat-4052	142	11	surgical	surgical	ADJ
easat-4052	142	12	excision	excision	NOUN
easat-4052	142	13	of	of	ADP
easat-4052	142	14	inflamed	inflame	VERB
easat-4052	142	15	tissue	tissue	NOUN
easat-4052	142	16	in	in	ADP
easat-4052	142	17	knee	knee	NOUN
easat-4052	142	18	arthroscopy	arthroscopy	NOUN
easat-4052	142	19	procedures	procedure	NOUN
easat-4052	142	20	.	.	PUNCT
easat-4052	143	1	furthermore	furthermore	ADV
easat-4052	143	2	,	,	PUNCT
easat-4052	143	3	ifpf	ifpf	NOUN
easat-4052	143	4	-	-	PUNCT
easat-4052	143	5	derived	derive	VERB
easat-4052	143	6	mscs	msc	NOUN
easat-4052	143	7	exhibit	exhibit	VERB
easat-4052	143	8	similar	similar	ADJ
easat-4052	143	9	surface	surface	NOUN
easat-4052	143	10	marker	marker	NOUN
easat-4052	143	11	profiles	profile	NOUN
easat-4052	143	12	to	to	ADP
easat-4052	143	13	cells	cell	NOUN
easat-4052	143	14	within	within	ADP
easat-4052	143	15	the	the	DET
easat-4052	143	16	knee	knee	NOUN
easat-4052	143	17	joint	joint	PROPN
easat-4052	143	18	environment	environment	NOUN
easat-4052	143	19	,	,	PUNCT
easat-4052	143	20	potentially	potentially	ADV
easat-4052	143	21	minimizing	minimize	VERB
easat-4052	143	22	the	the	DET
easat-4052	143	23	risk	risk	NOUN
easat-4052	143	24	of	of	ADP
easat-4052	143	25	immunological	immunological	ADJ
easat-4052	143	26	rejection	rejection	NOUN
easat-4052	143	27	[	[	X
easat-4052	143	28	18	18	NUM
easat-4052	143	29	]	]	PUNCT
easat-4052	143	30	.	.	PUNCT
easat-4052	144	1	the	the	DET
easat-4052	144	2	isolation	isolation	NOUN
easat-4052	144	3	and	and	CCONJ
easat-4052	144	4	culture	culture	NOUN
easat-4052	144	5	of	of	ADP
easat-4052	144	6	admscs	admscs	NOUN
easat-4052	144	7	are	be	AUX
easat-4052	144	8	performed	perform	VERB
easat-4052	144	9	following	follow	VERB
easat-4052	144	10	standardized	standardized	ADJ
easat-4052	144	11	protocols	protocol	NOUN
easat-4052	144	12	,	,	PUNCT
easat-4052	144	13	which	which	PRON
easat-4052	144	14	typically	typically	ADV
easat-4052	144	15	involve	involve	VERB
easat-4052	144	16	washing	wash	VERB
easat-4052	144	17	the	the	DET
easat-4052	144	18	tissue	tissue	NOUN
easat-4052	144	19	with	with	ADP
easat-4052	144	20	phosphate	phosphate	NOUN
easat-4052	144	21	-	-	PUNCT
easat-4052	144	22	buffered	buffer	VERB
easat-4052	144	23	saline	saline	NOUN
easat-4052	144	24	(	(	PUNCT
easat-4052	144	25	pbs	pbs	PROPN
easat-4052	144	26	)	)	PUNCT
easat-4052	144	27	,	,	PUNCT
easat-4052	144	28	enzymatic	enzymatic	ADJ
easat-4052	144	29	digestion	digestion	NOUN
easat-4052	144	30	of	of	ADP
easat-4052	144	31	fat	fat	ADJ
easat-4052	144	32	aspirates	aspirate	NOUN
easat-4052	144	33	using	use	VERB
easat-4052	144	34	0.075	0.075	NUM
easat-4052	144	35	%	%	NOUN
easat-4052	144	36	collagenase	collagenase	NOUN
easat-4052	144	37	,	,	PUNCT
easat-4052	144	38	and	and	CCONJ
easat-4052	144	39	subsequent	subsequent	ADJ
easat-4052	144	40	culturing	culturing	NOUN
easat-4052	144	41	in	in	ADP
easat-4052	144	42	a	a	DET
easat-4052	144	43	medium	medium	NOUN
easat-4052	144	44	supplemented	supplement	VERB
easat-4052	144	45	with	with	ADP
easat-4052	144	46	10	10	NUM
easat-4052	144	47	%	%	NOUN
easat-4052	144	48	fetal	fetal	ADJ
easat-4052	144	49	bovine	bovine	NOUN
easat-4052	144	50	serum	serum	NOUN
easat-4052	144	51	(	(	PUNCT
easat-4052	144	52	fbs	fbs	PROPN
easat-4052	144	53	)	)	PUNCT
easat-4052	144	54	and	and	CCONJ
easat-4052	144	55	1	1	NUM
easat-4052	144	56	%	%	NOUN
easat-4052	144	57	antibiotics	antibiotic	NOUN
easat-4052	144	58	under	under	ADP
easat-4052	144	59	conditions	condition	NOUN
easat-4052	144	60	of	of	ADP
easat-4052	144	61	37	37	NUM
easat-4052	144	62	°	°	NOUN
easat-4052	144	63	c	c	NOUN
easat-4052	144	64	and	and	CCONJ
easat-4052	144	65	5	5	NUM
easat-4052	144	66	%	%	NOUN
easat-4052	144	67	co2	co2	NOUN
easat-4052	144	68	for	for	ADP
easat-4052	144	69	30	30	NUM
easat-4052	144	70	-	-	SYM
easat-4052	144	71	60	60	NUM
easat-4052	144	72	minutes	minute	NOUN
easat-4052	144	73	[	[	X
easat-4052	144	74	25,26	25,26	X
easat-4052	144	75	]	]	X
easat-4052	144	76	.	.	PUNCT
easat-4052	145	1	a	a	DET
easat-4052	145	2	critical	critical	ADJ
easat-4052	145	3	aspect	aspect	NOUN
easat-4052	145	4	of	of	ADP
easat-4052	145	5	this	this	DET
easat-4052	145	6	process	process	NOUN
easat-4052	145	7	is	be	AUX
easat-4052	145	8	the	the	DET
easat-4052	145	9	identification	identification	NOUN
easat-4052	145	10	and	and	CCONJ
easat-4052	145	11	characterization	characterization	NOUN
easat-4052	145	12	of	of	ADP
easat-4052	145	13	admscs	admscs	NOUN
easat-4052	145	14	via	via	ADP
easat-4052	145	15	flow	flow	NOUN
easat-4052	145	16	cytometry	cytometry	NOUN
easat-4052	145	17	analysis	analysis	NOUN
easat-4052	145	18	of	of	ADP
easat-4052	145	19	specific	specific	ADJ
easat-4052	145	20	cell	cell	NOUN
easat-4052	145	21	surface	surface	NOUN
easat-4052	145	22	markers	marker	NOUN
easat-4052	146	1	[	[	X
easat-4052	146	2	25,29	25,29	NUM
easat-4052	146	3	]	]	X
easat-4052	146	4	.	.	PUNCT
easat-4052	147	1	the	the	DET
easat-4052	147	2	international	international	ADJ
easat-4052	147	3	society	society	NOUN
easat-4052	147	4	for	for	ADP
easat-4052	147	5	cell	cell	NOUN
easat-4052	147	6	therapy	therapy	NOUN
easat-4052	147	7	(	(	PUNCT
easat-4052	147	8	isct	isct	NOUN
easat-4052	147	9	)	)	PUNCT
easat-4052	147	10	and	and	CCONJ
easat-4052	147	11	the	the	DET
easat-4052	147	12	international	international	PROPN
easat-4052	147	13	federation	federation	PROPN
easat-4052	147	14	of	of	ADP
easat-4052	147	15	fat	fat	NOUN
easat-4052	147	16	therapy	therapy	NOUN
easat-4052	147	17	and	and	CCONJ
easat-4052	147	18	science	science	NOUN
easat-4052	147	19	(	(	PUNCT
easat-4052	147	20	ifats	ifat	NOUN
easat-4052	147	21	)	)	PUNCT
easat-4052	147	22	have	have	AUX
easat-4052	147	23	outlined	outline	VERB
easat-4052	147	24	three	three	NUM
easat-4052	147	25	fundamental	fundamental	ADJ
easat-4052	147	26	criteria	criterion	NOUN
easat-4052	147	27	for	for	ADP
easat-4052	147	28	defining	define	VERB
easat-4052	147	29	ascs	asc	NOUN
easat-4052	147	30	:	:	PUNCT
easat-4052	147	31	(	(	PUNCT
easat-4052	147	32	1	1	X
easat-4052	147	33	)	)	PUNCT
easat-4052	147	34	the	the	DET
easat-4052	147	35	cells	cell	NOUN
easat-4052	147	36	must	must	AUX
easat-4052	147	37	adhere	adhere	VERB
easat-4052	147	38	to	to	ADP
easat-4052	147	39	plastic	plastic	ADJ
easat-4052	147	40	surfaces	surface	NOUN
easat-4052	147	41	;	;	PUNCT
easat-4052	147	42	(	(	PUNCT
easat-4052	147	43	2	2	X
easat-4052	147	44	)	)	PUNCT
easat-4052	147	45	they	they	PRON
easat-4052	147	46	must	must	AUX
easat-4052	147	47	express	express	VERB
easat-4052	147	48	markers	marker	NOUN
easat-4052	147	49	such	such	ADJ
easat-4052	147	50	as	as	ADP
easat-4052	147	51	cd73	cd73	PROPN
easat-4052	147	52	,	,	PUNCT
easat-4052	147	53	cd90	cd90	PROPN
easat-4052	147	54	,	,	PUNCT
easat-4052	147	55	and	and	CCONJ
easat-4052	147	56	cd105	cd105	PROPN
easat-4052	147	57	while	while	SCONJ
easat-4052	147	58	lacking	lack	VERB
easat-4052	147	59	expression	expression	NOUN
easat-4052	147	60	of	of	ADP
easat-4052	147	61	cd14	cd14	PROPN
easat-4052	147	62	,	,	PUNCT
easat-4052	147	63	cd11b	cd11b	NOUN
easat-4052	147	64	,	,	PUNCT
easat-4052	147	65	cd45	cd45	PROPN
easat-4052	147	66	,	,	PUNCT
easat-4052	147	67	cd19	cd19	PROPN
easat-4052	147	68	,	,	PUNCT
easat-4052	147	69	cd79	cd79	PROPN
easat-4052	147	70	,	,	PUNCT
easat-4052	147	71	and	and	CCONJ
easat-4052	147	72	hla	hla	PROPN
easat-4052	147	73	-	-	PUNCT
easat-4052	147	74	dr	dr	PROPN
easat-4052	147	75	;	;	PUNCT
easat-4052	147	76	(	(	PUNCT
easat-4052	147	77	3	3	X
easat-4052	147	78	)	)	PUNCT
easat-4052	147	79	they	they	PRON
easat-4052	147	80	must	must	AUX
easat-4052	147	81	possess	possess	VERB
easat-4052	147	82	the	the	DET
easat-4052	147	83	ability	ability	NOUN
easat-4052	147	84	to	to	PART
easat-4052	147	85	differentiate	differentiate	VERB
easat-4052	147	86	into	into	ADP
easat-4052	147	87	adipogenic	adipogenic	ADJ
easat-4052	147	88	,	,	PUNCT
easat-4052	147	89	chondrogenic	chondrogenic	ADJ
easat-4052	147	90	,	,	PUNCT
easat-4052	147	91	and	and	CCONJ
easat-4052	147	92	osteogenic	osteogenic	ADJ
easat-4052	147	93	lineages	lineage	NOUN
easat-4052	147	94	.	.	PUNCT
easat-4052	148	1	based	base	VERB
easat-4052	148	2	on	on	ADP
easat-4052	148	3	the	the	DET
easat-4052	148	4	distinct	distinct	ADJ
easat-4052	148	5	properties	property	NOUN
easat-4052	148	6	of	of	ADP
easat-4052	148	7	the	the	DET
easat-4052	148	8	derived	derive	VERB
easat-4052	148	9	cells	cell	NOUN
easat-4052	148	10	,	,	PUNCT
easat-4052	148	11	various	various	ADJ
easat-4052	148	12	9599	9599	NUM
easat-4052	148	13	edelweiss	edelweiss	PROPN
easat-4052	148	14	applied	apply	VERB
easat-4052	148	15	science	science	NOUN
easat-4052	148	16	and	and	CCONJ
easat-4052	148	17	technology	technology	NOUN
easat-4052	148	18	issn	issn	PROPN
easat-4052	148	19	:	:	PUNCT
easat-4052	148	20	2576	2576	NUM
easat-4052	148	21	-	-	SYM
easat-4052	148	22	8484	8484	NUM
easat-4052	148	23	vol	vol	NOUN
easat-4052	148	24	.	.	PROPN
easat-4052	148	25	8	8	NUM
easat-4052	148	26	,	,	PUNCT
easat-4052	148	27	no	no	INTJ
easat-4052	148	28	.	.	NOUN
easat-4052	149	1	6	6	NUM
easat-4052	149	2	:	:	SYM
easat-4052	149	3	9592	9592	NUM
easat-4052	149	4	-	-	SYM
easat-4052	149	5	9604	9604	NUM
easat-4052	149	6	,	,	PUNCT
easat-4052	149	7	2024	2024	NUM
easat-4052	149	8	doi	doi	NOUN
easat-4052	149	9	:	:	PUNCT
easat-4052	149	10	10.55214/25768484.v8i6.4052	10.55214/25768484.v8i6.4052	NUM
easat-4052	150	1	©	©	ADP
easat-4052	150	2	2024	2024	NUM
easat-4052	150	3	by	by	ADP
easat-4052	150	4	the	the	DET
easat-4052	150	5	authors	author	NOUN
easat-4052	150	6	;	;	PUNCT
easat-4052	150	7	licensee	licensee	PROPN
easat-4052	150	8	learning	learning	NOUN
easat-4052	150	9	gate	gate	NOUN
easat-4052	150	10	targeted	target	VERB
easat-4052	150	11	detection	detection	NOUN
easat-4052	150	12	techniques	technique	NOUN
easat-4052	150	13	can	can	AUX
easat-4052	150	14	be	be	AUX
easat-4052	150	15	employed	employ	VERB
easat-4052	150	16	,	,	PUNCT
easat-4052	150	17	and	and	CCONJ
easat-4052	150	18	relevant	relevant	ADJ
easat-4052	150	19	animal	animal	NOUN
easat-4052	150	20	models	model	NOUN
easat-4052	150	21	can	can	AUX
easat-4052	150	22	be	be	AUX
easat-4052	150	23	established	establish	VERB
easat-4052	150	24	.	.	PUNCT
easat-4052	151	1	for	for	ADP
easat-4052	151	2	instance	instance	NOUN
easat-4052	151	3	,	,	PUNCT
easat-4052	151	4	assays	assay	NOUN
easat-4052	151	5	like	like	ADP
easat-4052	151	6	the	the	DET
easat-4052	151	7	3-(4,5)-dimethyl	3-(4,5)-dimethyl	PROPN
easat-4052	151	8	thiazole(-z	thiazole(-z	NOUN
easat-4052	151	9	-	-	PUNCT
easat-4052	151	10	y1)-3,5	y1)-3,5	NOUN
easat-4052	151	11	-	-	PUNCT
easat-4052	151	12	diphenyl	diphenyl	NOUN
easat-4052	151	13	triazolam	triazolam	NOUN
easat-4052	151	14	(	(	PUNCT
easat-4052	151	15	mtt	mtt	NOUN
easat-4052	151	16	)	)	PUNCT
easat-4052	151	17	test	test	NOUN
easat-4052	151	18	and	and	CCONJ
easat-4052	151	19	woundhealing	woundheale	VERB
easat-4052	151	20	models	model	NOUN
easat-4052	151	21	are	be	AUX
easat-4052	151	22	suitable	suitable	ADJ
easat-4052	151	23	for	for	ADP
easat-4052	151	24	fibroblast	fibroblast	ADJ
easat-4052	151	25	studies	study	NOUN
easat-4052	151	26	,	,	PUNCT
easat-4052	151	27	while	while	SCONJ
easat-4052	151	28	functional	functional	ADJ
easat-4052	151	29	assessments	assessment	NOUN
easat-4052	151	30	of	of	ADP
easat-4052	151	31	re	re	NOUN
easat-4052	151	32	-	-	NOUN
easat-4052	151	33	innervation	innervation	NOUN
easat-4052	151	34	can	can	AUX
easat-4052	151	35	be	be	AUX
easat-4052	151	36	used	use	VERB
easat-4052	151	37	to	to	PART
easat-4052	151	38	evaluate	evaluate	VERB
easat-4052	151	39	peripheral	peripheral	ADJ
easat-4052	151	40	nerve	nerve	NOUN
easat-4052	151	41	regeneration	regeneration	NOUN
easat-4052	151	42	[	[	X
easat-4052	151	43	25,26	25,26	NUM
easat-4052	151	44	]	]	X
easat-4052	151	45	.	.	PUNCT
easat-4052	152	1	the	the	DET
easat-4052	152	2	following	follow	VERB
easat-4052	152	3	outlines	outline	VERB
easat-4052	152	4	the	the	DET
easat-4052	152	5	steps	step	NOUN
easat-4052	152	6	involved	involve	VERB
easat-4052	152	7	and	and	CCONJ
easat-4052	152	8	their	their	PRON
easat-4052	152	9	respective	respective	ADJ
easat-4052	152	10	timeframes	timeframe	NOUN
easat-4052	152	11	when	when	SCONJ
easat-4052	152	12	utilizing	utilize	VERB
easat-4052	152	13	standard	standard	ADJ
easat-4052	152	14	protocols	protocol	NOUN
easat-4052	152	15	(	(	PUNCT
easat-4052	152	16	figure	figure	NOUN
easat-4052	152	17	1	1	NUM
easat-4052	152	18	)	)	PUNCT
easat-4052	153	1	[	[	X
easat-4052	153	2	30	30	NUM
easat-4052	153	3	]	]	PUNCT
easat-4052	153	4	.	.	PUNCT
easat-4052	154	1	figure	figure	NOUN
easat-4052	154	2	1	1	NUM
easat-4052	154	3	.	.	PUNCT
easat-4052	155	1	protocol	protocol	NOUN
easat-4052	155	2	for	for	ADP
easat-4052	155	3	isolating	isolate	VERB
easat-4052	155	4	admscs	admscs	NOUN
easat-4052	155	5	with	with	ADP
easat-4052	155	6	associated	associated	ADJ
easat-4052	155	7	timeframes	timeframe	NOUN
easat-4052	155	8	[	[	X
easat-4052	155	9	30	30	NUM
easat-4052	155	10	]	]	PUNCT
easat-4052	155	11	.	.	PUNCT
easat-4052	156	1	culturing	culture	VERB
easat-4052	156	2	admscs	admscs	NOUN
easat-4052	156	3	in	in	ADP
easat-4052	156	4	an	an	DET
easat-4052	156	5	osteogenic	osteogenic	ADJ
easat-4052	156	6	medium	medium	NOUN
easat-4052	156	7	is	be	AUX
easat-4052	156	8	the	the	DET
easat-4052	156	9	method	method	NOUN
easat-4052	156	10	most	most	ADV
easat-4052	156	11	frequently	frequently	ADV
easat-4052	156	12	described	describe	VERB
easat-4052	156	13	for	for	ADP
easat-4052	156	14	differentiating	differentiate	VERB
easat-4052	156	15	them	they	PRON
easat-4052	156	16	into	into	ADP
easat-4052	156	17	the	the	DET
easat-4052	156	18	osteogenic	osteogenic	ADJ
easat-4052	156	19	lineage	lineage	NOUN
easat-4052	156	20	.	.	PUNCT
easat-4052	157	1	usually	usually	ADV
easat-4052	157	2	,	,	PUNCT
easat-4052	157	3	a	a	DET
easat-4052	157	4	standard	standard	ADJ
easat-4052	157	5	base	base	NOUN
easat-4052	157	6	medium	medium	NOUN
easat-4052	157	7	,	,	PUNCT
easat-4052	157	8	like	like	ADP
easat-4052	157	9	dulbecco	dulbecco	NOUN
easat-4052	157	10	's	's	PART
easat-4052	157	11	modified	modify	VERB
easat-4052	157	12	eagle	eagle	NOUN
easat-4052	157	13	's	's	PART
easat-4052	157	14	medium	medium	ADJ
easat-4052	157	15	(	(	PUNCT
easat-4052	157	16	dmem	dmem	ADJ
easat-4052	157	17	)	)	PUNCT
easat-4052	157	18	or	or	CCONJ
easat-4052	157	19	minimum	minimum	ADJ
easat-4052	157	20	essential	essential	ADJ
easat-4052	157	21	medium	medium	ADJ
easat-4052	157	22	alpha	alpha	NOUN
easat-4052	157	23	(	(	PUNCT
easat-4052	157	24	α	α	NOUN
easat-4052	157	25	-	-	PUNCT
easat-4052	157	26	mem	mem	ADJ
easat-4052	157	27	)	)	PUNCT
easat-4052	157	28	,	,	PUNCT
easat-4052	157	29	is	be	AUX
easat-4052	157	30	used	use	VERB
easat-4052	157	31	to	to	PART
easat-4052	157	32	prepare	prepare	VERB
easat-4052	157	33	this	this	DET
easat-4052	157	34	medium	medium	NOUN
easat-4052	157	35	.	.	PUNCT
easat-4052	158	1	it	it	PRON
easat-4052	158	2	is	be	AUX
easat-4052	158	3	then	then	ADV
easat-4052	158	4	supplemented	supplement	VERB
easat-4052	158	5	with	with	ADP
easat-4052	158	6	phosphates	phosphate	NOUN
easat-4052	158	7	(	(	PUNCT
easat-4052	158	8	like	like	ADP
easat-4052	158	9	β	β	NOUN
easat-4052	158	10	-	-	NOUN
easat-4052	158	11	glycerophosphate	glycerophosphate	NOUN
easat-4052	158	12	)	)	PUNCT
easat-4052	158	13	,	,	PUNCT
easat-4052	158	14	ascorbates	ascorbate	VERB
easat-4052	158	15	(	(	PUNCT
easat-4052	158	16	like	like	ADP
easat-4052	158	17	ascorbic	ascorbic	NOUN
easat-4052	158	18	acid	acid	NOUN
easat-4052	158	19	or	or	CCONJ
easat-4052	158	20	ascorbate-2	ascorbate-2	NUM
easat-4052	158	21	-	-	NOUN
easat-4052	158	22	phosphate	phosphate	NOUN
easat-4052	158	23	)	)	PUNCT
easat-4052	158	24	,	,	PUNCT
easat-4052	158	25	inductive	inductive	ADJ
easat-4052	158	26	factors	factor	NOUN
easat-4052	158	27	(	(	PUNCT
easat-4052	158	28	like	like	ADP
easat-4052	158	29	dexamethasone	dexamethasone	NOUN
easat-4052	158	30	)	)	PUNCT
easat-4052	158	31	,	,	PUNCT
easat-4052	158	32	and	and	CCONJ
easat-4052	158	33	serum	serum	NOUN
easat-4052	158	34	(	(	PUNCT
easat-4052	158	35	like	like	INTJ
easat-4052	158	36	fetal	fetal	ADJ
easat-4052	158	37	bovine	bovine	NOUN
easat-4052	158	38	serum	serum	NOUN
easat-4052	158	39	)	)	PUNCT
easat-4052	159	1	[	[	X
easat-4052	159	2	25,26	25,26	X
easat-4052	159	3	]	]	PUNCT
easat-4052	159	4	.	.	PUNCT
easat-4052	160	1	soluble	soluble	ADJ
easat-4052	160	2	substances	substance	NOUN
easat-4052	160	3	such	such	ADJ
easat-4052	160	4	as	as	ADP
easat-4052	160	5	bmps	bmp	NOUN
easat-4052	160	6	,	,	PUNCT
easat-4052	160	7	vitamin	vitamin	NOUN
easat-4052	160	8	d3	d3	PROPN
easat-4052	160	9	,	,	PUNCT
easat-4052	160	10	platelet	platelet	ADJ
easat-4052	160	11	-	-	PUNCT
easat-4052	160	12	rich	rich	ADJ
easat-4052	160	13	plasma	plasma	NOUN
easat-4052	160	14	,	,	PUNCT
easat-4052	160	15	human	human	ADJ
easat-4052	160	16	platelet	platelet	NOUN
easat-4052	160	17	lysate	lysate	NOUN
easat-4052	160	18	,	,	PUNCT
easat-4052	160	19	selenium	selenium	NOUN
easat-4052	160	20	,	,	PUNCT
easat-4052	160	21	or	or	CCONJ
easat-4052	160	22	inorganic	inorganic	ADJ
easat-4052	160	23	ionic	ionic	ADJ
easat-4052	160	24	products	product	NOUN
easat-4052	160	25	like	like	ADP
easat-4052	160	26	calcium	calcium	NOUN
easat-4052	160	27	,	,	PUNCT
easat-4052	160	28	hydroxyapatite	hydroxyapatite	NOUN
easat-4052	160	29	,	,	PUNCT
easat-4052	160	30	strontium	strontium	NOUN
easat-4052	160	31	,	,	PUNCT
easat-4052	160	32	or	or	CCONJ
easat-4052	160	33	magnesium	magnesium	NOUN
easat-4052	160	34	can	can	AUX
easat-4052	160	35	all	all	PRON
easat-4052	160	36	further	far	ADV
easat-4052	160	37	promote	promote	VERB
easat-4052	160	38	osteogenic	osteogenic	ADJ
easat-4052	160	39	differentiation	differentiation	NOUN
easat-4052	160	40	.	.	PUNCT
easat-4052	161	1	additionally	additionally	ADV
easat-4052	161	2	,	,	PUNCT
easat-4052	161	3	the	the	DET
easat-4052	161	4	surface	surface	NOUN
easat-4052	161	5	properties	property	NOUN
easat-4052	161	6	of	of	ADP
easat-4052	161	7	the	the	DET
easat-4052	161	8	scaffold	scaffold	NOUN
easat-4052	161	9	or	or	CCONJ
easat-4052	161	10	ecm	ecm	NOUN
easat-4052	161	11	significantly	significantly	ADV
easat-4052	161	12	affect	affect	VERB
easat-4052	161	13	osteogenic	osteogenic	ADJ
easat-4052	161	14	differentiation	differentiation	NOUN
easat-4052	161	15	.	.	PUNCT
easat-4052	162	1	key	key	ADJ
easat-4052	162	2	factors	factor	NOUN
easat-4052	162	3	include	include	VERB
easat-4052	162	4	fiber	fiber	NOUN
easat-4052	162	5	alignment	alignment	NOUN
easat-4052	162	6	,	,	PUNCT
easat-4052	162	7	stiffness	stiffness	NOUN
easat-4052	162	8	,	,	PUNCT
easat-4052	162	9	porosity	porosity	NOUN
easat-4052	162	10	,	,	PUNCT
easat-4052	162	11	and	and	CCONJ
easat-4052	162	12	chemical	chemical	NOUN
easat-4052	162	13	composition	composition	NOUN
easat-4052	162	14	.	.	PUNCT
easat-4052	163	1	external	external	ADJ
easat-4052	163	2	stimuli	stimulus	NOUN
easat-4052	163	3	,	,	PUNCT
easat-4052	163	4	such	such	ADJ
easat-4052	163	5	as	as	ADP
easat-4052	163	6	acoustic	acoustic	ADJ
easat-4052	163	7	waves	wave	NOUN
easat-4052	163	8	,	,	PUNCT
easat-4052	163	9	electromagnetic	electromagnetic	ADJ
easat-4052	163	10	fields	field	NOUN
easat-4052	163	11	,	,	PUNCT
easat-4052	163	12	and	and	CCONJ
easat-4052	163	13	shear	shear	NOUN
easat-4052	163	14	stress	stress	NOUN
easat-4052	163	15	,	,	PUNCT
easat-4052	163	16	also	also	ADV
easat-4052	163	17	influence	influence	VERB
easat-4052	163	18	the	the	DET
easat-4052	163	19	differentiation	differentiation	NOUN
easat-4052	163	20	process	process	NOUN
easat-4052	163	21	[	[	X
easat-4052	163	22	26	26	NUM
easat-4052	163	23	]	]	PUNCT
easat-4052	163	24	.	.	PUNCT
easat-4052	164	1	4.3	4.3	NUM
easat-4052	164	2	.	.	PUNCT
easat-4052	164	3	role	role	NOUN
easat-4052	164	4	of	of	ADP
easat-4052	164	5	admscs	admscs	NOUN
easat-4052	164	6	in	in	ADP
easat-4052	164	7	cartilage	cartilage	NOUN
easat-4052	164	8	regeneration	regeneration	NOUN
easat-4052	164	9	admscs	admscs	NOUN
easat-4052	164	10	are	be	AUX
easat-4052	164	11	extensively	extensively	ADV
easat-4052	164	12	employed	employ	VERB
easat-4052	164	13	in	in	ADP
easat-4052	164	14	cartilage	cartilage	NOUN
easat-4052	164	15	regeneration	regeneration	NOUN
easat-4052	164	16	due	due	ADP
easat-4052	164	17	to	to	ADP
easat-4052	164	18	their	their	PRON
easat-4052	164	19	high	high	ADJ
easat-4052	164	20	abundance	abundance	NOUN
easat-4052	164	21	,	,	PUNCT
easat-4052	164	22	ease	ease	NOUN
easat-4052	164	23	of	of	ADP
easat-4052	164	24	accessibility	accessibility	NOUN
easat-4052	164	25	,	,	PUNCT
easat-4052	164	26	and	and	CCONJ
easat-4052	164	27	robust	robust	ADJ
easat-4052	164	28	capacity	capacity	NOUN
easat-4052	164	29	for	for	ADP
easat-4052	164	30	in	in	ADP
easat-4052	164	31	vitro	vitro	X
easat-4052	164	32	proliferation	proliferation	NOUN
easat-4052	164	33	and	and	CCONJ
easat-4052	164	34	differentiation	differentiation	NOUN
easat-4052	164	35	[	[	X
easat-4052	164	36	31	31	NUM
easat-4052	164	37	]	]	PUNCT
easat-4052	164	38	.	.	PUNCT
easat-4052	165	1	the	the	DET
easat-4052	165	2	therapeutic	therapeutic	ADJ
easat-4052	165	3	potential	potential	NOUN
easat-4052	165	4	of	of	ADP
easat-4052	165	5	admscs	admsc	NOUN
easat-4052	165	6	,	,	PUNCT
easat-4052	165	7	including	include	VERB
easat-4052	165	8	their	their	PRON
easat-4052	165	9	capacity	capacity	NOUN
easat-4052	165	10	for	for	ADP
easat-4052	165	11	tissue	tissue	NOUN
easat-4052	165	12	repair	repair	NOUN
easat-4052	165	13	and	and	CCONJ
easat-4052	165	14	differentiation	differentiation	NOUN
easat-4052	165	15	into	into	ADP
easat-4052	165	16	various	various	ADJ
easat-4052	165	17	cell	cell	NOUN
easat-4052	165	18	lineages	lineage	NOUN
easat-4052	165	19	,	,	PUNCT
easat-4052	165	20	has	have	AUX
easat-4052	165	21	facilitated	facilitate	VERB
easat-4052	165	22	their	their	PRON
easat-4052	165	23	expanded	expand	VERB
easat-4052	165	24	application	application	NOUN
easat-4052	165	25	across	across	ADP
easat-4052	165	26	multiple	multiple	ADJ
easat-4052	165	27	disciplines	discipline	NOUN
easat-4052	165	28	,	,	PUNCT
easat-4052	165	29	particularly	particularly	ADV
easat-4052	165	30	in	in	ADP
easat-4052	165	31	orthopaedics	orthopaedic	NOUN
easat-4052	165	32	[	[	X
easat-4052	165	33	13	13	NUM
easat-4052	165	34	]	]	PUNCT
easat-4052	165	35	.	.	PUNCT
easat-4052	166	1	admscs	admscs	PROPN
easat-4052	166	2	can	can	AUX
easat-4052	166	3	be	be	AUX
easat-4052	166	4	harvested	harvest	VERB
easat-4052	166	5	from	from	ADP
easat-4052	166	6	various	various	ADJ
easat-4052	166	7	anatomical	anatomical	ADJ
easat-4052	166	8	locations	location	NOUN
easat-4052	166	9	,	,	PUNCT
easat-4052	166	10	including	include	VERB
easat-4052	166	11	the	the	DET
easat-4052	166	12	upper	upper	ADJ
easat-4052	166	13	arm	arm	NOUN
easat-4052	166	14	,	,	PUNCT
easat-4052	166	15	medial	medial	ADJ
easat-4052	166	16	thigh	thigh	NOUN
easat-4052	166	17	,	,	PUNCT
easat-4052	166	18	buttocks	buttock	NOUN
easat-4052	166	19	,	,	PUNCT
easat-4052	166	20	trochanteric	trochanteric	ADJ
easat-4052	166	21	region	region	NOUN
easat-4052	166	22	,	,	PUNCT
easat-4052	166	23	superficial	superficial	ADJ
easat-4052	166	24	and	and	CCONJ
easat-4052	166	25	deep	deep	ADJ
easat-4052	166	26	abdominal	abdominal	ADJ
easat-4052	166	27	fat	fat	ADJ
easat-4052	166	28	depots	depot	NOUN
easat-4052	166	29	,	,	PUNCT
easat-4052	166	30	and	and	CCONJ
easat-4052	166	31	the	the	DET
easat-4052	166	32	infrapatellar	infrapatellar	ADJ
easat-4052	166	33	fat	fat	ADJ
easat-4052	166	34	pad	pad	NOUN
easat-4052	166	35	(	(	PUNCT
easat-4052	166	36	ipfp	ipfp	NOUN
easat-4052	166	37	)	)	PUNCT
easat-4052	166	38	of	of	ADP
easat-4052	166	39	the	the	DET
easat-4052	166	40	knee	knee	NOUN
easat-4052	166	41	joint	joint	NOUN
easat-4052	166	42	.	.	PUNCT
easat-4052	167	1	the	the	DET
easat-4052	167	2	svf	svf	PROPN
easat-4052	167	3	contains	contain	VERB
easat-4052	167	4	approximately	approximately	ADV
easat-4052	167	5	2	2	NUM
easat-4052	167	6	to	to	PART
easat-4052	167	7	6	6	NUM
easat-4052	167	8	million	million	NUM
easat-4052	167	9	cells	cell	NOUN
easat-4052	167	10	,	,	PUNCT
easat-4052	167	11	which	which	PRON
easat-4052	167	12	can	can	AUX
easat-4052	167	13	be	be	AUX
easat-4052	167	14	extracted	extract	VERB
easat-4052	167	15	from	from	ADP
easat-4052	167	16	1	1	NUM
easat-4052	167	17	ml	ml	NOUN
easat-4052	167	18	of	of	ADP
easat-4052	167	19	lipoaspirate	lipoaspirate	NOUN
easat-4052	167	20	.	.	PUNCT
easat-4052	168	1	the	the	DET
easat-4052	168	2	concentration	concentration	NOUN
easat-4052	168	3	of	of	ADP
easat-4052	168	4	admscs	admscs	NOUN
easat-4052	168	5	within	within	ADP
easat-4052	168	6	adipose	adipose	ADJ
easat-4052	168	7	tissue	tissue	NOUN
easat-4052	168	8	can	can	AUX
easat-4052	168	9	vary	vary	VERB
easat-4052	168	10	,	,	PUNCT
easat-4052	168	11	ranging	range	VERB
easat-4052	168	12	from	from	ADP
easat-4052	168	13	5,000	5,000	NUM
easat-4052	168	14	to	to	PART
easat-4052	168	15	200,000	200,000	NUM
easat-4052	168	16	cells	cell	NOUN
easat-4052	168	17	per	per	ADP
easat-4052	168	18	gram	gram	NOUN
easat-4052	169	1	[	[	X
easat-4052	169	2	32	32	NUM
easat-4052	169	3	]	]	PUNCT
easat-4052	169	4	.	.	PUNCT
easat-4052	170	1	admscs	admscs	PROPN
easat-4052	170	2	,	,	PUNCT
easat-4052	170	3	owing	owe	VERB
easat-4052	170	4	to	to	ADP
easat-4052	170	5	their	their	PRON
easat-4052	170	6	mesodermal	mesodermal	ADJ
easat-4052	170	7	9600	9600	NUM
easat-4052	170	8	edelweiss	edelweiss	PROPN
easat-4052	170	9	applied	apply	VERB
easat-4052	170	10	science	science	NOUN
easat-4052	170	11	and	and	CCONJ
easat-4052	170	12	technology	technology	NOUN
easat-4052	170	13	issn	issn	PROPN
easat-4052	170	14	:	:	PUNCT
easat-4052	170	15	2576	2576	NUM
easat-4052	170	16	-	-	SYM
easat-4052	170	17	8484	8484	NUM
easat-4052	170	18	vol	vol	NOUN
easat-4052	170	19	.	.	PROPN
easat-4052	171	1	8	8	NUM
easat-4052	171	2	,	,	PUNCT
easat-4052	171	3	no	no	INTJ
easat-4052	171	4	.	.	NOUN
easat-4052	172	1	6	6	NUM
easat-4052	172	2	:	:	SYM
easat-4052	172	3	9592	9592	NUM
easat-4052	172	4	-	-	SYM
easat-4052	172	5	9604	9604	NUM
easat-4052	172	6	,	,	PUNCT
easat-4052	172	7	2024	2024	NUM
easat-4052	172	8	doi	doi	NOUN
easat-4052	172	9	:	:	PUNCT
easat-4052	172	10	10.55214/25768484.v8i6.4052	10.55214/25768484.v8i6.4052	NUM
easat-4052	173	1	©	©	ADP
easat-4052	173	2	2024	2024	NUM
easat-4052	173	3	by	by	ADP
easat-4052	173	4	the	the	DET
easat-4052	173	5	authors	author	NOUN
easat-4052	173	6	;	;	PUNCT
easat-4052	173	7	licensee	licensee	PROPN
easat-4052	173	8	learning	learning	PROPN
easat-4052	173	9	gate	gate	PROPN
easat-4052	173	10	origin	origin	NOUN
easat-4052	173	11	,	,	PUNCT
easat-4052	173	12	possess	possess	VERB
easat-4052	173	13	the	the	DET
easat-4052	173	14	ability	ability	NOUN
easat-4052	173	15	to	to	PART
easat-4052	173	16	differentiate	differentiate	VERB
easat-4052	173	17	into	into	ADP
easat-4052	173	18	adipocytes	adipocyte	NOUN
easat-4052	173	19	,	,	PUNCT
easat-4052	173	20	osteoblasts	osteoblast	NOUN
easat-4052	173	21	,	,	PUNCT
easat-4052	173	22	chondrocytes	chondrocyte	NOUN
easat-4052	173	23	,	,	PUNCT
easat-4052	173	24	and	and	CCONJ
easat-4052	173	25	endothelial	endothelial	ADJ
easat-4052	173	26	cells	cell	NOUN
easat-4052	173	27	.	.	PUNCT
easat-4052	174	1	furthermore	furthermore	ADV
easat-4052	174	2	,	,	PUNCT
easat-4052	174	3	studies	study	NOUN
easat-4052	174	4	have	have	AUX
easat-4052	174	5	shown	show	VERB
easat-4052	174	6	that	that	SCONJ
easat-4052	174	7	admscs	admscs	NOUN
easat-4052	174	8	can	can	AUX
easat-4052	174	9	also	also	ADV
easat-4052	174	10	differentiate	differentiate	VERB
easat-4052	174	11	into	into	ADP
easat-4052	174	12	cells	cell	NOUN
easat-4052	174	13	of	of	ADP
easat-4052	174	14	ectodermal	ectodermal	ADJ
easat-4052	174	15	and	and	CCONJ
easat-4052	174	16	endodermal	endodermal	ADJ
easat-4052	174	17	origin	origin	NOUN
easat-4052	174	18	,	,	PUNCT
easat-4052	174	19	including	include	VERB
easat-4052	174	20	vascular	vascular	ADJ
easat-4052	174	21	smooth	smooth	ADJ
easat-4052	174	22	muscle	muscle	NOUN
easat-4052	174	23	cells	cell	NOUN
easat-4052	174	24	,	,	PUNCT
easat-4052	174	25	keratinocytes	keratinocyte	NOUN
easat-4052	174	26	,	,	PUNCT
easat-4052	174	27	hepatocytes	hepatocyte	NOUN
easat-4052	174	28	,	,	PUNCT
easat-4052	174	29	beta	beta	NOUN
easat-4052	174	30	-	-	PUNCT
easat-4052	174	31	islet	islet	NOUN
easat-4052	174	32	cells	cell	NOUN
easat-4052	174	33	,	,	PUNCT
easat-4052	174	34	neuron	neuron	NOUN
easat-4052	174	35	-	-	PUNCT
easat-4052	174	36	like	like	ADJ
easat-4052	174	37	cells	cell	NOUN
easat-4052	174	38	,	,	PUNCT
easat-4052	174	39	and	and	CCONJ
easat-4052	174	40	glial	glial	ADJ
easat-4052	174	41	lineages	lineage	NOUN
easat-4052	174	42	[	[	X
easat-4052	174	43	30,32,33	30,32,33	NUM
easat-4052	174	44	]	]	PUNCT
easat-4052	174	45	.	.	PUNCT
easat-4052	175	1	the	the	DET
easat-4052	175	2	principal	principal	ADJ
easat-4052	175	3	benefit	benefit	NOUN
easat-4052	175	4	of	of	ADP
easat-4052	175	5	autologous	autologous	ADJ
easat-4052	175	6	-	-	PUNCT
easat-4052	175	7	cultured	cultured	ADJ
easat-4052	175	8	admscs	admscs	NOUN
easat-4052	175	9	is	be	AUX
easat-4052	175	10	their	their	PRON
easat-4052	175	11	ability	ability	NOUN
easat-4052	175	12	to	to	PART
easat-4052	175	13	provide	provide	VERB
easat-4052	175	14	rapid	rapid	ADJ
easat-4052	175	15	pain	pain	NOUN
easat-4052	175	16	relief	relief	NOUN
easat-4052	175	17	while	while	SCONJ
easat-4052	175	18	contributing	contribute	VERB
easat-4052	175	19	to	to	ADP
easat-4052	175	20	substantial	substantial	ADJ
easat-4052	175	21	improvements	improvement	NOUN
easat-4052	175	22	in	in	ADP
easat-4052	175	23	knee	knee	NOUN
easat-4052	175	24	function	function	NOUN
easat-4052	175	25	and	and	CCONJ
easat-4052	175	26	cartilage	cartilage	NOUN
easat-4052	175	27	regeneration	regeneration	NOUN
easat-4052	175	28	over	over	ADP
easat-4052	175	29	time	time	NOUN
easat-4052	175	30	[	[	X
easat-4052	175	31	33	33	NUM
easat-4052	175	32	]	]	PUNCT
easat-4052	175	33	.	.	PUNCT
easat-4052	176	1	in	in	ADP
easat-4052	176	2	the	the	DET
easat-4052	176	3	process	process	NOUN
easat-4052	176	4	of	of	ADP
easat-4052	176	5	cartilage	cartilage	NOUN
easat-4052	176	6	regeneration	regeneration	NOUN
easat-4052	176	7	,	,	PUNCT
easat-4052	176	8	admscs	admsc	NOUN
easat-4052	176	9	secrete	secrete	VERB
easat-4052	176	10	a	a	DET
easat-4052	176	11	diverse	diverse	ADJ
easat-4052	176	12	array	array	NOUN
easat-4052	176	13	of	of	ADP
easat-4052	176	14	paracrine	paracrine	NOUN
easat-4052	176	15	factors	factor	NOUN
easat-4052	176	16	collectively	collectively	ADV
easat-4052	176	17	referred	refer	VERB
easat-4052	176	18	to	to	ADP
easat-4052	176	19	as	as	ADP
easat-4052	176	20	the	the	DET
easat-4052	176	21	secretome	secretome	NOUN
easat-4052	176	22	.	.	PUNCT
easat-4052	177	1	this	this	DET
easat-4052	177	2	secretome	secretome	NOUN
easat-4052	177	3	includes	include	VERB
easat-4052	177	4	various	various	ADJ
easat-4052	177	5	proteins	protein	NOUN
easat-4052	177	6	that	that	PRON
easat-4052	177	7	perform	perform	VERB
easat-4052	177	8	critical	critical	ADJ
easat-4052	177	9	biological	biological	ADJ
easat-4052	177	10	functions	function	NOUN
easat-4052	177	11	such	such	ADJ
easat-4052	177	12	as	as	ADP
easat-4052	177	13	immune	immune	ADJ
easat-4052	177	14	modulation	modulation	NOUN
easat-4052	177	15	,	,	PUNCT
easat-4052	177	16	angiogenesis	angiogenesis	NOUN
easat-4052	177	17	,	,	PUNCT
easat-4052	177	18	anti	anti	ADJ
easat-4052	177	19	-	-	ADJ
easat-4052	177	20	apoptosis	apoptosis	ADJ
easat-4052	177	21	,	,	PUNCT
easat-4052	177	22	antioxidation	antioxidation	NOUN
easat-4052	177	23	,	,	PUNCT
easat-4052	177	24	cell	cell	NOUN
easat-4052	177	25	homing	homing	NOUN
easat-4052	177	26	,	,	PUNCT
easat-4052	177	27	and	and	CCONJ
easat-4052	177	28	the	the	DET
easat-4052	177	29	promotion	promotion	NOUN
easat-4052	177	30	of	of	ADP
easat-4052	177	31	cell	cell	NOUN
easat-4052	177	32	differentiation	differentiation	NOUN
easat-4052	177	33	.	.	PUNCT
easat-4052	178	1	admscs	admscs	PROPN
easat-4052	178	2	release	release	VERB
easat-4052	178	3	cytokines	cytokine	NOUN
easat-4052	178	4	to	to	PART
easat-4052	178	5	initiate	initiate	VERB
easat-4052	178	6	cartilage	cartilage	NOUN
easat-4052	178	7	repair	repair	NOUN
easat-4052	178	8	,	,	PUNCT
easat-4052	178	9	which	which	PRON
easat-4052	178	10	is	be	AUX
easat-4052	178	11	subsequently	subsequently	ADV
easat-4052	178	12	enhanced	enhance	VERB
easat-4052	178	13	by	by	ADP
easat-4052	178	14	chondrogenic	chondrogenic	ADJ
easat-4052	178	15	proliferation	proliferation	NOUN
easat-4052	178	16	and	and	CCONJ
easat-4052	178	17	the	the	DET
easat-4052	178	18	secretion	secretion	NOUN
easat-4052	178	19	of	of	ADP
easat-4052	178	20	ecm	ecm	NOUN
easat-4052	178	21	proteases	protease	NOUN
easat-4052	178	22	and	and	CCONJ
easat-4052	178	23	growth	growth	NOUN
easat-4052	178	24	factors	factor	NOUN
easat-4052	178	25	,	,	PUNCT
easat-4052	178	26	including	include	VERB
easat-4052	178	27	tgf	tgf	PROPN
easat-4052	178	28	-	-	PUNCT
easat-4052	178	29	β	β	NOUN
easat-4052	178	30	,	,	PUNCT
easat-4052	178	31	igf-1	igf-1	NOUN
easat-4052	178	32	,	,	PUNCT
easat-4052	178	33	and	and	CCONJ
easat-4052	178	34	fibroblast	fibroblast	ADJ
easat-4052	178	35	growth	growth	NOUN
easat-4052	178	36	factor	factor	NOUN
easat-4052	178	37	(	(	PUNCT
easat-4052	178	38	fgf	fgf	PROPN
easat-4052	178	39	)	)	PUNCT
easat-4052	178	40	.	.	PUNCT
easat-4052	179	1	these	these	DET
easat-4052	179	2	components	component	NOUN
easat-4052	179	3	of	of	ADP
easat-4052	179	4	the	the	DET
easat-4052	179	5	secretome	secretome	NOUN
easat-4052	179	6	play	play	VERB
easat-4052	179	7	a	a	DET
easat-4052	179	8	pivotal	pivotal	ADJ
easat-4052	179	9	role	role	NOUN
easat-4052	179	10	in	in	ADP
easat-4052	179	11	stimulating	stimulate	VERB
easat-4052	179	12	and	and	CCONJ
easat-4052	179	13	facilitating	facilitate	VERB
easat-4052	179	14	cartilage	cartilage	NOUN
easat-4052	179	15	repair	repair	NOUN
easat-4052	179	16	[	[	X
easat-4052	179	17	33,34	33,34	NOUN
easat-4052	179	18	]	]	X
easat-4052	179	19	.	.	PUNCT
easat-4052	180	1	the	the	DET
easat-4052	180	2	paracrine	paracrine	NOUN
easat-4052	180	3	factors	factor	NOUN
easat-4052	180	4	secreted	secrete	VERB
easat-4052	180	5	by	by	ADP
easat-4052	180	6	admscs	admscs	NOUN
easat-4052	180	7	may	may	AUX
easat-4052	180	8	be	be	AUX
easat-4052	180	9	encapsulated	encapsulate	VERB
easat-4052	180	10	within	within	ADP
easat-4052	180	11	extracellular	extracellular	ADJ
easat-4052	180	12	vesicle	vesicle	NOUN
easat-4052	180	13	(	(	PUNCT
easat-4052	180	14	evs	evs	PROPN
easat-4052	180	15	)	)	PUNCT
easat-4052	180	16	,	,	PUNCT
easat-4052	180	17	which	which	PRON
easat-4052	180	18	are	be	AUX
easat-4052	180	19	complex	complex	ADJ
easat-4052	180	20	structures	structure	NOUN
easat-4052	180	21	containing	contain	VERB
easat-4052	180	22	a	a	DET
easat-4052	180	23	variety	variety	NOUN
easat-4052	180	24	of	of	ADP
easat-4052	180	25	biomolecules	biomolecule	NOUN
easat-4052	180	26	,	,	PUNCT
easat-4052	180	27	including	include	VERB
easat-4052	180	28	lipids	lipid	NOUN
easat-4052	180	29	,	,	PUNCT
easat-4052	180	30	proteins	protein	NOUN
easat-4052	180	31	,	,	PUNCT
easat-4052	180	32	rna	rna	NOUN
easat-4052	180	33	(	(	PUNCT
easat-4052	180	34	both	both	CCONJ
easat-4052	180	35	mrna	mrna	PROPN
easat-4052	180	36	and	and	CCONJ
easat-4052	180	37	noncoding	noncoding	ADJ
easat-4052	180	38	rnas	rna	NOUN
easat-4052	180	39	)	)	PUNCT
easat-4052	180	40	,	,	PUNCT
easat-4052	180	41	and	and	CCONJ
easat-4052	180	42	specific	specific	ADJ
easat-4052	180	43	dna	dna	PROPN
easat-4052	180	44	subtypes	subtype	NOUN
easat-4052	180	45	.	.	PUNCT
easat-4052	181	1	the	the	DET
easat-4052	181	2	biological	biological	ADJ
easat-4052	181	3	properties	property	NOUN
easat-4052	181	4	of	of	ADP
easat-4052	181	5	evs	evs	NOUN
easat-4052	181	6	enable	enable	VERB
easat-4052	181	7	them	they	PRON
easat-4052	181	8	to	to	PART
easat-4052	181	9	cross	cross	VERB
easat-4052	181	10	the	the	DET
easat-4052	181	11	blood	blood	NOUN
easat-4052	181	12	-	-	PUNCT
easat-4052	181	13	brain	brain	NOUN
easat-4052	181	14	barrier	barrier	NOUN
easat-4052	181	15	(	(	PUNCT
easat-4052	181	16	bbb	bbb	NOUN
easat-4052	181	17	)	)	PUNCT
easat-4052	181	18	,	,	PUNCT
easat-4052	181	19	achieve	achieve	VERB
easat-4052	181	20	targeted	target	VERB
easat-4052	181	21	delivery	delivery	NOUN
easat-4052	181	22	to	to	ADP
easat-4052	181	23	specific	specific	ADJ
easat-4052	181	24	cells	cell	NOUN
easat-4052	181	25	,	,	PUNCT
easat-4052	181	26	and	and	CCONJ
easat-4052	181	27	safeguard	safeguard	VERB
easat-4052	181	28	their	their	PRON
easat-4052	181	29	molecular	molecular	ADJ
easat-4052	181	30	cargo	cargo	NOUN
easat-4052	181	31	from	from	ADP
easat-4052	181	32	degradation	degradation	NOUN
easat-4052	181	33	during	during	ADP
easat-4052	181	34	circulation	circulation	NOUN
easat-4052	181	35	[	[	X
easat-4052	181	36	34,35	34,35	NOUN
easat-4052	181	37	]	]	PUNCT
easat-4052	181	38	.	.	PUNCT
easat-4052	182	1	in	in	ADP
easat-4052	182	2	addition	addition	NOUN
easat-4052	182	3	to	to	ADP
easat-4052	182	4	their	their	PRON
easat-4052	182	5	ability	ability	NOUN
easat-4052	182	6	to	to	PART
easat-4052	182	7	differentiate	differentiate	VERB
easat-4052	182	8	and	and	CCONJ
easat-4052	182	9	exert	exert	VERB
easat-4052	182	10	paracrine	paracrine	NOUN
easat-4052	182	11	effects	effect	NOUN
easat-4052	182	12	,	,	PUNCT
easat-4052	182	13	admscs	admsc	NOUN
easat-4052	182	14	possess	possess	VERB
easat-4052	182	15	immunomodulatory	immunomodulatory	ADJ
easat-4052	182	16	functions	function	NOUN
easat-4052	182	17	,	,	PUNCT
easat-4052	182	18	which	which	PRON
easat-4052	182	19	play	play	VERB
easat-4052	182	20	a	a	DET
easat-4052	182	21	crucial	crucial	ADJ
easat-4052	182	22	role	role	NOUN
easat-4052	182	23	in	in	ADP
easat-4052	182	24	cartilage	cartilage	NOUN
easat-4052	182	25	repair	repair	NOUN
easat-4052	182	26	.	.	PUNCT
easat-4052	183	1	given	give	VERB
easat-4052	183	2	that	that	SCONJ
easat-4052	183	3	damaged	damage	VERB
easat-4052	183	4	cartilage	cartilage	NOUN
easat-4052	183	5	is	be	AUX
easat-4052	183	6	often	often	ADV
easat-4052	183	7	subjected	subject	VERB
easat-4052	183	8	to	to	ADP
easat-4052	183	9	a	a	DET
easat-4052	183	10	chronic	chronic	ADJ
easat-4052	183	11	inflammatory	inflammatory	ADJ
easat-4052	183	12	environment	environment	NOUN
easat-4052	183	13	,	,	PUNCT
easat-4052	183	14	its	its	PRON
easat-4052	183	15	ability	ability	NOUN
easat-4052	183	16	to	to	PART
easat-4052	183	17	modulate	modulate	VERB
easat-4052	183	18	the	the	DET
easat-4052	183	19	immune	immune	ADJ
easat-4052	183	20	response	response	NOUN
easat-4052	183	21	contributes	contribute	VERB
easat-4052	183	22	significantly	significantly	ADV
easat-4052	183	23	to	to	ADP
easat-4052	183	24	the	the	DET
easat-4052	183	25	repair	repair	NOUN
easat-4052	183	26	process	process	NOUN
easat-4052	183	27	.	.	PUNCT
easat-4052	184	1	admscs	admscs	PROPN
easat-4052	184	2	are	be	AUX
easat-4052	184	3	known	know	VERB
easat-4052	184	4	for	for	ADP
easat-4052	184	5	their	their	PRON
easat-4052	184	6	low	low	ADJ
easat-4052	184	7	immunogenicity	immunogenicity	NOUN
easat-4052	184	8	,	,	PUNCT
easat-4052	184	9	resulting	result	VERB
easat-4052	184	10	in	in	ADP
easat-4052	184	11	a	a	DET
easat-4052	184	12	weak	weak	ADJ
easat-4052	184	13	immune	immune	ADJ
easat-4052	184	14	response	response	NOUN
easat-4052	184	15	,	,	PUNCT
easat-4052	184	16	primarily	primarily	ADV
easat-4052	184	17	due	due	ADP
easat-4052	184	18	to	to	ADP
easat-4052	184	19	their	their	PRON
easat-4052	184	20	lack	lack	NOUN
easat-4052	184	21	of	of	ADP
easat-4052	184	22	major	major	ADJ
easat-4052	184	23	histocompatibility	histocompatibility	NOUN
easat-4052	184	24	complex	complex	NOUN
easat-4052	184	25	(	(	PUNCT
easat-4052	184	26	mhc	mhc	PROPN
easat-4052	184	27	)	)	PUNCT
easat-4052	184	28	class	class	NOUN
easat-4052	184	29	ii	ii	NOUN
easat-4052	184	30	expression	expression	NOUN
easat-4052	184	31	and	and	CCONJ
easat-4052	184	32	the	the	DET
easat-4052	184	33	absence	absence	NOUN
easat-4052	184	34	of	of	ADP
easat-4052	184	35	classic	classic	ADJ
easat-4052	184	36	costimulatory	costimulatory	NOUN
easat-4052	184	37	molecules	molecule	NOUN
easat-4052	184	38	such	such	ADJ
easat-4052	184	39	as	as	ADP
easat-4052	184	40	cd80	cd80	PROPN
easat-4052	184	41	,	,	PUNCT
easat-4052	184	42	cd86	cd86	PROPN
easat-4052	184	43	,	,	PUNCT
easat-4052	184	44	and	and	CCONJ
easat-4052	184	45	cd40	cd40	PROPN
easat-4052	185	1	[	[	X
easat-4052	185	2	31,36	31,36	NUM
easat-4052	185	3	]	]	PUNCT
easat-4052	185	4	.	.	PUNCT
easat-4052	186	1	furthermore	furthermore	ADV
easat-4052	186	2	,	,	PUNCT
easat-4052	186	3	when	when	SCONJ
easat-4052	186	4	exposed	expose	VERB
easat-4052	186	5	to	to	ADP
easat-4052	186	6	injured	injured	ADJ
easat-4052	186	7	tissue	tissue	NOUN
easat-4052	186	8	or	or	CCONJ
easat-4052	186	9	inflammatory	inflammatory	ADJ
easat-4052	186	10	cytokines	cytokine	NOUN
easat-4052	186	11	,	,	PUNCT
easat-4052	186	12	admscs	admscs	PROPN
easat-4052	186	13	can	can	AUX
easat-4052	186	14	exert	exert	VERB
easat-4052	186	15	immunomodulatory	immunomodulatory	ADJ
easat-4052	186	16	effects	effect	NOUN
easat-4052	186	17	on	on	ADP
easat-4052	186	18	various	various	ADJ
easat-4052	186	19	immune	immune	ADJ
easat-4052	186	20	cells	cell	NOUN
easat-4052	186	21	.	.	PUNCT
easat-4052	187	1	it	it	PRON
easat-4052	187	2	has	have	AUX
easat-4052	187	3	been	be	AUX
easat-4052	187	4	shown	show	VERB
easat-4052	187	5	that	that	SCONJ
easat-4052	187	6	specific	specific	ADJ
easat-4052	187	7	cell	cell	NOUN
easat-4052	187	8	surface	surface	NOUN
easat-4052	187	9	molecules	molecule	NOUN
easat-4052	187	10	,	,	PUNCT
easat-4052	187	11	such	such	ADJ
easat-4052	187	12	as	as	ADP
easat-4052	187	13	programmed	program	VERB
easat-4052	187	14	death	death	NOUN
easat-4052	187	15	-	-	PUNCT
easat-4052	187	16	ligand	ligand	NOUN
easat-4052	187	17	1	1	NUM
easat-4052	187	18	(	(	PUNCT
easat-4052	187	19	pd	pd	NOUN
easat-4052	187	20	-	-	PUNCT
easat-4052	187	21	l1	l1	NOUN
easat-4052	187	22	)	)	PUNCT
easat-4052	187	23	and	and	CCONJ
easat-4052	187	24	fas	fas	PROPN
easat-4052	187	25	ligand	ligand	PROPN
easat-4052	187	26	(	(	PUNCT
easat-4052	187	27	fasl	fasl	PROPN
easat-4052	187	28	)	)	PUNCT
easat-4052	187	29	,	,	PUNCT
easat-4052	187	30	mediate	mediate	VERB
easat-4052	187	31	the	the	DET
easat-4052	187	32	immunomodulatory	immunomodulatory	ADJ
easat-4052	187	33	functions	function	NOUN
easat-4052	187	34	of	of	ADP
easat-4052	187	35	admscs	admsc	NOUN
easat-4052	187	36	,	,	PUNCT
easat-4052	187	37	inhibiting	inhibit	VERB
easat-4052	187	38	t	t	NOUN
easat-4052	187	39	cell	cell	NOUN
easat-4052	187	40	immune	immune	ADJ
easat-4052	187	41	activity	activity	NOUN
easat-4052	187	42	upon	upon	SCONJ
easat-4052	187	43	binding	bind	VERB
easat-4052	187	44	.	.	PUNCT
easat-4052	188	1	in	in	ADP
easat-4052	188	2	addition	addition	NOUN
easat-4052	188	3	to	to	ADP
easat-4052	188	4	direct	direct	ADJ
easat-4052	188	5	cell	cell	NOUN
easat-4052	188	6	contact	contact	NOUN
easat-4052	188	7	,	,	PUNCT
easat-4052	188	8	admscs	admsc	NOUN
easat-4052	188	9	also	also	ADV
easat-4052	188	10	regulate	regulate	VERB
easat-4052	188	11	immune	immune	ADJ
easat-4052	188	12	cell	cell	NOUN
easat-4052	188	13	function	function	NOUN
easat-4052	188	14	through	through	ADP
easat-4052	188	15	the	the	DET
easat-4052	188	16	secretion	secretion	NOUN
easat-4052	188	17	of	of	ADP
easat-4052	188	18	cytokines	cytokine	NOUN
easat-4052	188	19	.	.	PUNCT
easat-4052	189	1	for	for	ADP
easat-4052	189	2	instance	instance	NOUN
easat-4052	189	3	,	,	PUNCT
easat-4052	189	4	interferon	interferon	ADJ
easat-4052	189	5	-	-	PUNCT
easat-4052	189	6	gamma	gamma	NOUN
easat-4052	189	7	(	(	PUNCT
easat-4052	189	8	ifn	ifn	PROPN
easat-4052	189	9	-	-	PUNCT
easat-4052	189	10	γ	γ	NOUN
easat-4052	189	11	)	)	PUNCT
easat-4052	189	12	can	can	AUX
easat-4052	189	13	upregulate	upregulate	VERB
easat-4052	189	14	indoleamine	indoleamine	ADJ
easat-4052	189	15	2,3	2,3	NUM
easat-4052	189	16	-	-	NOUN
easat-4052	189	17	dioxygenase	dioxygenase	NOUN
easat-4052	189	18	(	(	PUNCT
easat-4052	189	19	ido	ido	NOUN
easat-4052	189	20	)	)	PUNCT
easat-4052	189	21	expression	expression	NOUN
easat-4052	189	22	in	in	ADP
easat-4052	189	23	admscs	admscs	NOUN
easat-4052	189	24	via	via	ADP
easat-4052	189	25	the	the	DET
easat-4052	189	26	jak	jak	PROPN
easat-4052	189	27	-	-	PUNCT
easat-4052	189	28	stat1	stat1	PROPN
easat-4052	189	29	signaling	signal	VERB
easat-4052	189	30	pathway	pathway	NOUN
easat-4052	189	31	,	,	PUNCT
easat-4052	189	32	leading	lead	VERB
easat-4052	189	33	to	to	ADP
easat-4052	189	34	inhibition	inhibition	NOUN
easat-4052	189	35	of	of	ADP
easat-4052	189	36	peripheral	peripheral	ADJ
easat-4052	189	37	blood	blood	NOUN
easat-4052	189	38	mononuclear	mononuclear	ADJ
easat-4052	189	39	cell	cell	NOUN
easat-4052	189	40	(	(	PUNCT
easat-4052	189	41	pbmc	pbmc	NOUN
easat-4052	189	42	)	)	PUNCT
easat-4052	189	43	proliferation	proliferation	NOUN
easat-4052	189	44	and	and	CCONJ
easat-4052	189	45	promoting	promote	VERB
easat-4052	189	46	m2	m2	PROPN
easat-4052	189	47	macrophage	macrophage	ADJ
easat-4052	189	48	polarization	polarization	NOUN
easat-4052	189	49	[	[	X
easat-4052	189	50	31,35	31,35	NOUN
easat-4052	189	51	]	]	PUNCT
easat-4052	189	52	.	.	PUNCT
easat-4052	190	1	in	in	ADP
easat-4052	190	2	the	the	DET
easat-4052	190	3	presence	presence	NOUN
easat-4052	190	4	of	of	ADP
easat-4052	190	5	il-17a	il-17a	PROPN
easat-4052	190	6	,	,	PUNCT
easat-4052	190	7	admscs	admsc	NOUN
easat-4052	190	8	increase	increase	VERB
easat-4052	190	9	the	the	DET
easat-4052	190	10	expression	expression	NOUN
easat-4052	190	11	of	of	ADP
easat-4052	190	12	prostaglandin	prostaglandin	PROPN
easat-4052	190	13	e2	e2	PROPN
easat-4052	190	14	(	(	PUNCT
easat-4052	190	15	pge2	pge2	PROPN
easat-4052	190	16	)	)	PUNCT
easat-4052	190	17	and	and	CCONJ
easat-4052	190	18	significantly	significantly	ADV
easat-4052	190	19	enhance	enhance	VERB
easat-4052	190	20	the	the	DET
easat-4052	190	21	proportion	proportion	NOUN
easat-4052	190	22	of	of	ADP
easat-4052	190	23	cd4+foxp3	cd4+foxp3	X
easat-4052	190	24	+	+	X
easat-4052	190	25	regulatory	regulatory	ADJ
easat-4052	190	26	t	t	NOUN
easat-4052	190	27	cells	cell	NOUN
easat-4052	190	28	(	(	PUNCT
easat-4052	190	29	tregs	treg	NOUN
easat-4052	190	30	)	)	PUNCT
easat-4052	190	31	,	,	PUNCT
easat-4052	190	32	thereby	thereby	ADV
easat-4052	190	33	suppressing	suppress	VERB
easat-4052	190	34	t	t	NOUN
easat-4052	190	35	-	-	PUNCT
easat-4052	190	36	cell	cell	NOUN
easat-4052	190	37	proliferation	proliferation	NOUN
easat-4052	190	38	.	.	PUNCT
easat-4052	191	1	other	other	ADJ
easat-4052	191	2	molecules	molecule	NOUN
easat-4052	191	3	,	,	PUNCT
easat-4052	191	4	including	include	VERB
easat-4052	191	5	nitric	nitric	ADJ
easat-4052	191	6	oxide	oxide	NOUN
easat-4052	191	7	(	(	PUNCT
easat-4052	191	8	no	no	NOUN
easat-4052	191	9	)	)	PUNCT
easat-4052	191	10	,	,	PUNCT
easat-4052	191	11	inducible	inducible	ADJ
easat-4052	191	12	nitric	nitric	ADJ
easat-4052	191	13	oxide	oxide	NOUN
easat-4052	191	14	synthase	synthase	NOUN
easat-4052	191	15	(	(	PUNCT
easat-4052	191	16	inos	ino	NOUN
easat-4052	191	17	)	)	PUNCT
easat-4052	191	18	,	,	PUNCT
easat-4052	191	19	human	human	ADJ
easat-4052	191	20	leukocyte	leukocyte	NOUN
easat-4052	191	21	antigen	antigen	NOUN
easat-4052	191	22	-	-	PUNCT
easat-4052	191	23	g	g	NOUN
easat-4052	191	24	(	(	PUNCT
easat-4052	191	25	hla	hla	NOUN
easat-4052	191	26	-	-	PUNCT
easat-4052	191	27	g	g	NOUN
easat-4052	191	28	)	)	PUNCT
easat-4052	191	29	,	,	PUNCT
easat-4052	191	30	and	and	CCONJ
easat-4052	191	31	il-10	il-10	PRON
easat-4052	191	32	,	,	PUNCT
easat-4052	191	33	have	have	AUX
easat-4052	191	34	also	also	ADV
easat-4052	191	35	been	be	AUX
easat-4052	191	36	implicated	implicate	VERB
easat-4052	191	37	in	in	ADP
easat-4052	191	38	mediating	mediate	VERB
easat-4052	191	39	the	the	DET
easat-4052	191	40	immunosuppressive	immunosuppressive	ADJ
easat-4052	191	41	functions	function	NOUN
easat-4052	191	42	of	of	ADP
easat-4052	191	43	admscs	admscs	NOUN
easat-4052	191	44	[	[	X
easat-4052	191	45	31,36	31,36	NUM
easat-4052	191	46	]	]	PUNCT
easat-4052	191	47	.	.	PUNCT
easat-4052	192	1	in	in	ADP
easat-4052	192	2	summary	summary	NOUN
easat-4052	192	3	,	,	PUNCT
easat-4052	192	4	the	the	DET
easat-4052	192	5	process	process	NOUN
easat-4052	192	6	of	of	ADP
easat-4052	192	7	cartilage	cartilage	NOUN
easat-4052	192	8	regeneration	regeneration	NOUN
easat-4052	192	9	is	be	AUX
easat-4052	192	10	influenced	influence	VERB
easat-4052	192	11	by	by	ADP
easat-4052	192	12	a	a	DET
easat-4052	192	13	synergy	synergy	NOUN
easat-4052	192	14	of	of	ADP
easat-4052	192	15	paracrine	paracrine	NOUN
easat-4052	192	16	signaling	signal	VERB
easat-4052	192	17	,	,	PUNCT
easat-4052	192	18	cellular	cellular	ADJ
easat-4052	192	19	differentiation	differentiation	NOUN
easat-4052	192	20	,	,	PUNCT
easat-4052	192	21	and	and	CCONJ
easat-4052	192	22	repopulation	repopulation	NOUN
easat-4052	192	23	,	,	PUNCT
easat-4052	192	24	along	along	ADP
easat-4052	192	25	with	with	ADP
easat-4052	192	26	immunomodulatory	immunomodulatory	ADJ
easat-4052	192	27	functions	function	NOUN
easat-4052	193	1	[	[	X
easat-4052	193	2	20–23	20–23	NOUN
easat-4052	193	3	]	]	X
easat-4052	193	4	.	.	PUNCT
easat-4052	194	1	4.4	4.4	NUM
easat-4052	194	2	.	.	PUNCT
easat-4052	194	3	scaffolds	scaffold	NOUN
easat-4052	194	4	in	in	ADP
easat-4052	194	5	cartilage	cartilage	NOUN
easat-4052	194	6	regeneration	regeneration	NOUN
easat-4052	194	7	scaffolds	scaffold	NOUN
easat-4052	194	8	play	play	VERB
easat-4052	194	9	a	a	DET
easat-4052	194	10	pivotal	pivotal	ADJ
easat-4052	194	11	role	role	NOUN
easat-4052	194	12	in	in	ADP
easat-4052	194	13	tissue	tissue	NOUN
easat-4052	194	14	engineering	engineering	NOUN
easat-4052	194	15	strategies	strategy	NOUN
easat-4052	194	16	for	for	ADP
easat-4052	194	17	oc	oc	NOUN
easat-4052	194	18	repair	repair	NOUN
easat-4052	194	19	.	.	PUNCT
easat-4052	195	1	to	to	PART
easat-4052	195	2	ensure	ensure	VERB
easat-4052	195	3	high	high	ADJ
easat-4052	195	4	-	-	PUNCT
easat-4052	195	5	quality	quality	NOUN
easat-4052	195	6	tissue	tissue	NOUN
easat-4052	195	7	regeneration	regeneration	NOUN
easat-4052	195	8	,	,	PUNCT
easat-4052	195	9	scaffolds	scaffold	NOUN
easat-4052	195	10	must	must	AUX
easat-4052	195	11	possess	possess	VERB
easat-4052	195	12	several	several	ADJ
easat-4052	195	13	key	key	ADJ
easat-4052	195	14	characteristics	characteristic	NOUN
easat-4052	195	15	:	:	PUNCT
easat-4052	195	16	a	a	DET
easat-4052	195	17	porous	porous	ADJ
easat-4052	195	18	structure	structure	NOUN
easat-4052	195	19	to	to	PART
easat-4052	195	20	support	support	VERB
easat-4052	195	21	cell	cell	NOUN
easat-4052	195	22	survival	survival	NOUN
easat-4052	195	23	and	and	CCONJ
easat-4052	195	24	facilitate	facilitate	VERB
easat-4052	195	25	nutrient	nutrient	NOUN
easat-4052	195	26	and	and	CCONJ
easat-4052	195	27	waste	waste	NOUN
easat-4052	195	28	transport	transport	NOUN
easat-4052	195	29	;	;	PUNCT
easat-4052	195	30	a	a	DET
easat-4052	195	31	surface	surface	NOUN
easat-4052	195	32	conducive	conducive	ADJ
easat-4052	195	33	to	to	ADP
easat-4052	195	34	cell	cell	NOUN
easat-4052	195	35	adhesion	adhesion	NOUN
easat-4052	195	36	,	,	PUNCT
easat-4052	195	37	proliferation	proliferation	NOUN
easat-4052	195	38	,	,	PUNCT
easat-4052	195	39	and	and	CCONJ
easat-4052	195	40	differentiation	differentiation	NOUN
easat-4052	195	41	;	;	PUNCT
easat-4052	195	42	mechanical	mechanical	ADJ
easat-4052	195	43	properties	property	NOUN
easat-4052	195	44	that	that	PRON
easat-4052	195	45	match	match	VERB
easat-4052	195	46	those	those	PRON
easat-4052	195	47	of	of	ADP
easat-4052	195	48	the	the	DET
easat-4052	195	49	surrounding	surround	VERB
easat-4052	195	50	tissue	tissue	NOUN
easat-4052	195	51	;	;	PUNCT
easat-4052	195	52	biocompatibility	biocompatibility	NOUN
easat-4052	195	53	to	to	PART
easat-4052	195	54	minimize	minimize	VERB
easat-4052	195	55	immune	immune	ADJ
easat-4052	195	56	reactions	reaction	NOUN
easat-4052	195	57	;	;	PUNCT
easat-4052	195	58	and	and	CCONJ
easat-4052	195	59	bio	bio	NOUN
easat-4052	195	60	-	-	NOUN
easat-4052	195	61	absorbability	absorbability	NOUN
easat-4052	195	62	with	with	ADP
easat-4052	195	63	a	a	DET
easat-4052	195	64	controllable	controllable	ADJ
easat-4052	195	65	degradation	degradation	NOUN
easat-4052	195	66	rate	rate	NOUN
easat-4052	195	67	to	to	PART
easat-4052	195	68	align	align	VERB
easat-4052	195	69	with	with	ADP
easat-4052	195	70	the	the	DET
easat-4052	195	71	tissue	tissue	NOUN
easat-4052	195	72	regeneration	regeneration	NOUN
easat-4052	195	73	process	process	NOUN
easat-4052	195	74	[	[	X
easat-4052	195	75	37	37	NUM
easat-4052	195	76	]	]	PUNCT
easat-4052	195	77	.	.	PUNCT
easat-4052	196	1	scaffold	scaffold	NOUN
easat-4052	196	2	-	-	PUNCT
easat-4052	196	3	based	base	VERB
easat-4052	196	4	delivery	delivery	NOUN
easat-4052	196	5	systems	system	NOUN
easat-4052	196	6	,	,	PUNCT
easat-4052	196	7	such	such	ADJ
easat-4052	196	8	as	as	ADP
easat-4052	196	9	fibrin	fibrin	NOUN
easat-4052	196	10	scaffolds	scaffold	NOUN
easat-4052	196	11	,	,	PUNCT
easat-4052	196	12	offer	offer	VERB
easat-4052	196	13	a	a	DET
easat-4052	196	14	structured	structured	ADJ
easat-4052	196	15	microenvironment	microenvironment	NOUN
easat-4052	196	16	for	for	ADP
easat-4052	196	17	admscs	admscs	NOUN
easat-4052	196	18	,	,	PUNCT
easat-4052	196	19	enhancing	enhance	VERB
easat-4052	196	20	cell	cell	NOUN
easat-4052	196	21	retention	retention	NOUN
easat-4052	196	22	and	and	CCONJ
easat-4052	196	23	facilitating	facilitate	VERB
easat-4052	196	24	more	more	ADV
easat-4052	196	25	effective	effective	ADJ
easat-4052	196	26	cartilage	cartilage	NOUN
easat-4052	196	27	regeneration	regeneration	NOUN
easat-4052	196	28	at	at	ADP
easat-4052	196	29	the	the	DET
easat-4052	196	30	injury	injury	NOUN
easat-4052	196	31	site	site	NOUN
easat-4052	196	32	[	[	X
easat-4052	196	33	32,33	32,33	NUM
easat-4052	196	34	]	]	PUNCT
easat-4052	196	35	.	.	PUNCT
easat-4052	197	1	scaffolds	scaffold	NOUN
easat-4052	197	2	replicate	replicate	VERB
easat-4052	197	3	the	the	DET
easat-4052	197	4	function	function	NOUN
easat-4052	197	5	of	of	ADP
easat-4052	197	6	the	the	DET
easat-4052	197	7	ecm	ecm	NOUN
easat-4052	197	8	by	by	ADP
easat-4052	197	9	directing	direct	VERB
easat-4052	197	10	admscs	admsc	NOUN
easat-4052	197	11	to	to	PART
easat-4052	197	12	effectively	effectively	ADV
easat-4052	197	13	integrate	integrate	VERB
easat-4052	197	14	into	into	ADP
easat-4052	197	15	the	the	DET
easat-4052	197	16	defect	defect	NOUN
easat-4052	197	17	site	site	NOUN
easat-4052	197	18	,	,	PUNCT
easat-4052	197	19	supporting	support	VERB
easat-4052	197	20	progenitor	progenitor	NOUN
easat-4052	197	21	cell	cell	NOUN
easat-4052	197	22	differentiation	differentiation	NOUN
easat-4052	197	23	while	while	SCONJ
easat-4052	197	24	offering	offer	VERB
easat-4052	197	25	mechanical	mechanical	ADJ
easat-4052	197	26	stability	stability	NOUN
easat-4052	197	27	.	.	PUNCT
easat-4052	198	1	scaffolds	scaffold	NOUN
easat-4052	198	2	composed	compose	VERB
easat-4052	198	3	of	of	ADP
easat-4052	198	4	osteoconductive	osteoconductive	ADJ
easat-4052	198	5	materials	material	NOUN
easat-4052	198	6	are	be	AUX
easat-4052	198	7	particularly	particularly	ADV
easat-4052	198	8	effective	effective	ADJ
easat-4052	198	9	with	with	ADP
easat-4052	198	10	partially	partially	ADV
easat-4052	198	11	differentiated	differentiated	ADJ
easat-4052	198	12	cells	cell	NOUN
easat-4052	198	13	,	,	PUNCT
easat-4052	198	14	such	such	ADJ
easat-4052	198	15	as	as	ADP
easat-4052	198	16	osteoblasts	osteoblast	NOUN
easat-4052	198	17	and	and	CCONJ
easat-4052	198	18	pre	pre	NOUN
easat-4052	198	19	-	-	NOUN
easat-4052	198	20	osteoblasts	osteoblast	NOUN
easat-4052	198	21	,	,	PUNCT
easat-4052	198	22	but	but	CCONJ
easat-4052	198	23	they	they	PRON
easat-4052	198	24	are	be	AUX
easat-4052	198	25	9601	9601	NUM
easat-4052	198	26	edelweiss	edelweiss	PROPN
easat-4052	198	27	applied	apply	VERB
easat-4052	198	28	science	science	NOUN
easat-4052	198	29	and	and	CCONJ
easat-4052	198	30	technology	technology	NOUN
easat-4052	198	31	issn	issn	PROPN
easat-4052	198	32	:	:	PUNCT
easat-4052	198	33	2576	2576	NUM
easat-4052	198	34	-	-	SYM
easat-4052	198	35	8484	8484	NUM
easat-4052	198	36	vol	vol	NOUN
easat-4052	198	37	.	.	PROPN
easat-4052	198	38	8	8	NUM
easat-4052	198	39	,	,	PUNCT
easat-4052	198	40	no	no	INTJ
easat-4052	198	41	.	.	NOUN
easat-4052	199	1	6	6	NUM
easat-4052	199	2	:	:	SYM
easat-4052	199	3	9592	9592	NUM
easat-4052	199	4	-	-	SYM
easat-4052	199	5	9604	9604	NUM
easat-4052	199	6	,	,	PUNCT
easat-4052	199	7	2024	2024	NUM
easat-4052	199	8	doi	doi	NOUN
easat-4052	199	9	:	:	PUNCT
easat-4052	199	10	10.55214/25768484.v8i6.4052	10.55214/25768484.v8i6.4052	NUM
easat-4052	200	1	©	©	ADP
easat-4052	200	2	2024	2024	NUM
easat-4052	200	3	by	by	ADP
easat-4052	200	4	the	the	DET
easat-4052	200	5	authors	author	NOUN
easat-4052	200	6	;	;	PUNCT
easat-4052	200	7	licensee	licensee	PROPN
easat-4052	200	8	learning	learning	NOUN
easat-4052	200	9	gate	gate	VERB
easat-4052	200	10	insufficient	insufficient	ADJ
easat-4052	200	11	to	to	PART
easat-4052	200	12	induce	induce	VERB
easat-4052	200	13	osteogenic	osteogenic	ADJ
easat-4052	200	14	differentiation	differentiation	NOUN
easat-4052	200	15	in	in	ADP
easat-4052	200	16	osseous	osseous	ADJ
easat-4052	200	17	progenitor	progenitor	NOUN
easat-4052	200	18	cells	cell	NOUN
easat-4052	200	19	and	and	CCONJ
easat-4052	200	20	admscs	admsc	NOUN
easat-4052	200	21	.	.	PUNCT
easat-4052	201	1	conversely	conversely	ADV
easat-4052	201	2	,	,	PUNCT
easat-4052	201	3	scaffolds	scaffold	NOUN
easat-4052	201	4	incorporating	incorporate	VERB
easat-4052	201	5	osteoinductive	osteoinductive	ADJ
easat-4052	201	6	biomaterials	biomaterial	NOUN
easat-4052	201	7	have	have	AUX
easat-4052	201	8	demonstrated	demonstrate	VERB
easat-4052	201	9	the	the	DET
easat-4052	201	10	ability	ability	NOUN
easat-4052	201	11	to	to	PART
easat-4052	201	12	recruit	recruit	VERB
easat-4052	201	13	progenitor	progenitor	NOUN
easat-4052	201	14	cells	cell	NOUN
easat-4052	201	15	and	and	CCONJ
easat-4052	201	16	enhance	enhance	VERB
easat-4052	201	17	osteoblastic	osteoblastic	ADJ
easat-4052	201	18	commitment	commitment	NOUN
easat-4052	201	19	and	and	CCONJ
easat-4052	201	20	differentiation	differentiation	NOUN
easat-4052	201	21	,	,	PUNCT
easat-4052	201	22	thereby	thereby	ADV
easat-4052	201	23	promoting	promote	VERB
easat-4052	201	24	bone	bone	NOUN
easat-4052	201	25	formation	formation	NOUN
easat-4052	201	26	[	[	X
easat-4052	201	27	26	26	NUM
easat-4052	201	28	]	]	PUNCT
easat-4052	201	29	.	.	PUNCT
easat-4052	202	1	several	several	ADJ
easat-4052	202	2	scaffold	scaffold	NOUN
easat-4052	202	3	fabrication	fabrication	NOUN
easat-4052	202	4	techniques	technique	NOUN
easat-4052	202	5	have	have	AUX
easat-4052	202	6	been	be	AUX
easat-4052	202	7	developed	develop	VERB
easat-4052	202	8	for	for	ADP
easat-4052	202	9	oc	oc	AUX
easat-4052	202	10	tissue	tissue	NOUN
easat-4052	202	11	engineering	engineering	NOUN
easat-4052	202	12	to	to	PART
easat-4052	202	13	improve	improve	VERB
easat-4052	202	14	scalability	scalability	NOUN
easat-4052	202	15	,	,	PUNCT
easat-4052	202	16	sustainability	sustainability	NOUN
easat-4052	202	17	,	,	PUNCT
easat-4052	202	18	and	and	CCONJ
easat-4052	202	19	spatial	spatial	ADJ
easat-4052	202	20	control	control	NOUN
easat-4052	202	21	.	.	PUNCT
easat-4052	203	1	these	these	DET
easat-4052	203	2	techniques	technique	NOUN
easat-4052	203	3	include	include	VERB
easat-4052	203	4	particulate	particulate	NOUN
easat-4052	203	5	leaching	leaching	NOUN
easat-4052	203	6	,	,	PUNCT
easat-4052	203	7	solvent	solvent	NOUN
easat-4052	203	8	casting	casting	NOUN
easat-4052	203	9	,	,	PUNCT
easat-4052	203	10	compression	compression	NOUN
easat-4052	203	11	molding	molding	NOUN
easat-4052	203	12	,	,	PUNCT
easat-4052	203	13	sol	sol	NOUN
easat-4052	203	14	-	-	PUNCT
easat-4052	203	15	gel	gel	NOUN
easat-4052	203	16	processing	processing	NOUN
easat-4052	203	17	,	,	PUNCT
easat-4052	203	18	lyophilization	lyophilization	NOUN
easat-4052	203	19	,	,	PUNCT
easat-4052	203	20	freeze	freeze	VERB
easat-4052	203	21	casting	casting	NOUN
easat-4052	203	22	,	,	PUNCT
easat-4052	203	23	gas	gas	NOUN
easat-4052	203	24	foaming	foaming	NOUN
easat-4052	203	25	,	,	PUNCT
easat-4052	203	26	and	and	CCONJ
easat-4052	203	27	phase	phase	NOUN
easat-4052	203	28	separation	separation	NOUN
easat-4052	203	29	.	.	PUNCT
easat-4052	204	1	to	to	PART
easat-4052	204	2	modify	modify	VERB
easat-4052	204	3	scaffold	scaffold	NOUN
easat-4052	204	4	characteristics	characteristic	NOUN
easat-4052	204	5	like	like	ADP
easat-4052	204	6	porosity	porosity	NOUN
easat-4052	204	7	,	,	PUNCT
easat-4052	204	8	mechanical	mechanical	ADJ
easat-4052	204	9	strength	strength	NOUN
easat-4052	204	10	,	,	PUNCT
easat-4052	204	11	and	and	CCONJ
easat-4052	204	12	structural	structural	ADJ
easat-4052	204	13	complexity	complexity	NOUN
easat-4052	204	14	to	to	PART
easat-4052	204	15	satisfy	satisfy	VERB
easat-4052	204	16	the	the	DET
easat-4052	204	17	needs	need	NOUN
easat-4052	204	18	of	of	ADP
easat-4052	204	19	oc	oc	ADP
easat-4052	204	20	tissue	tissue	NOUN
easat-4052	204	21	repair	repair	NOUN
easat-4052	204	22	,	,	PUNCT
easat-4052	204	23	each	each	DET
easat-4052	204	24	method	method	NOUN
easat-4052	204	25	has	have	VERB
easat-4052	204	26	special	special	ADJ
easat-4052	204	27	benefits	benefit	NOUN
easat-4052	204	28	[	[	X
easat-4052	204	29	37	37	NUM
easat-4052	204	30	]	]	PUNCT
easat-4052	204	31	.	.	PUNCT
easat-4052	205	1	materials	material	NOUN
easat-4052	205	2	used	use	VERB
easat-4052	205	3	in	in	ADP
easat-4052	205	4	scaffold	scaffold	NOUN
easat-4052	205	5	fabrication	fabrication	NOUN
easat-4052	205	6	range	range	NOUN
easat-4052	205	7	widely	widely	ADV
easat-4052	205	8	and	and	CCONJ
easat-4052	205	9	include	include	VERB
easat-4052	205	10	human	human	NOUN
easat-4052	205	11	-	-	PUNCT
easat-4052	205	12	derived	derive	VERB
easat-4052	205	13	allografts	allograft	NOUN
easat-4052	205	14	such	such	ADJ
easat-4052	205	15	as	as	ADP
easat-4052	205	16	bovine	bovine	NOUN
easat-4052	205	17	teeth	tooth	NOUN
easat-4052	205	18	,	,	PUNCT
easat-4052	205	19	alveolar	alveolar	ADJ
easat-4052	205	20	bone	bone	NOUN
easat-4052	205	21	,	,	PUNCT
easat-4052	205	22	heterogeneous	heterogeneous	ADJ
easat-4052	205	23	deproteinized	deproteinize	VERB
easat-4052	205	24	bone	bone	NOUN
easat-4052	205	25	(	(	PUNCT
easat-4052	205	26	hdb	hdb	NOUN
easat-4052	205	27	)	)	PUNCT
easat-4052	205	28	,	,	PUNCT
easat-4052	205	29	bovine	bovine	NOUN
easat-4052	205	30	bone	bone	NOUN
easat-4052	205	31	,	,	PUNCT
easat-4052	205	32	cortical	cortical	ADJ
easat-4052	205	33	bone	bone	NOUN
easat-4052	205	34	,	,	PUNCT
easat-4052	205	35	and	and	CCONJ
easat-4052	205	36	cancellous	cancellous	ADJ
easat-4052	205	37	bone	bone	NOUN
easat-4052	205	38	.	.	PUNCT
easat-4052	206	1	synthetic	synthetic	ADJ
easat-4052	206	2	materials	material	NOUN
easat-4052	206	3	are	be	AUX
easat-4052	206	4	also	also	ADV
easat-4052	206	5	extensively	extensively	ADV
easat-4052	206	6	employed	employ	VERB
easat-4052	206	7	,	,	PUNCT
easat-4052	206	8	including	include	VERB
easat-4052	206	9	pcl	pcl	PROPN
easat-4052	206	10	,	,	PUNCT
easat-4052	206	11	bioceramics	bioceramic	NOUN
easat-4052	206	12	,	,	PUNCT
easat-4052	206	13	polylactic	polylactic	ADJ
easat-4052	206	14	acid	acid	NOUN
easat-4052	206	15	(	(	PUNCT
easat-4052	206	16	pla	pla	NOUN
easat-4052	206	17	)	)	PUNCT
easat-4052	206	18	,	,	PUNCT
easat-4052	206	19	hydroxyapatite	hydroxyapatite	NOUN
easat-4052	206	20	,	,	PUNCT
easat-4052	206	21	coral	coral	ADJ
easat-4052	206	22	-	-	PUNCT
easat-4052	206	23	hydroxyapatite	hydroxyapatite	NOUN
easat-4052	206	24	(	(	PUNCT
easat-4052	206	25	cha	cha	NOUN
easat-4052	206	26	)	)	PUNCT
easat-4052	206	27	,	,	PUNCT
easat-4052	206	28	strontium	strontium	NOUN
easat-4052	206	29	hydroxyapatite	hydroxyapatite	NOUN
easat-4052	206	30	(	(	PUNCT
easat-4052	206	31	srha	srha	NOUN
easat-4052	206	32	)	)	PUNCT
easat-4052	206	33	,	,	PUNCT
easat-4052	206	34	titanium	titanium	NOUN
easat-4052	206	35	,	,	PUNCT
easat-4052	206	36	betatricalcium	betatricalcium	NOUN
easat-4052	206	37	phosphate	phosphate	NOUN
easat-4052	206	38	(	(	PUNCT
easat-4052	206	39	β	β	NOUN
easat-4052	206	40	-	-	PUNCT
easat-4052	206	41	tcp	tcp	NOUN
easat-4052	206	42	)	)	PUNCT
easat-4052	206	43	,	,	PUNCT
easat-4052	206	44	poly(lactide	poly(lactide	PROPN
easat-4052	206	45	-	-	PUNCT
easat-4052	206	46	co	co	NOUN
easat-4052	206	47	-	-	ADJ
easat-4052	206	48	glycolide	glycolide	ADJ
easat-4052	206	49	)	)	PUNCT
easat-4052	206	50	acid	acid	NOUN
easat-4052	206	51	(	(	PUNCT
easat-4052	206	52	plga	plga	NOUN
easat-4052	206	53	)	)	PUNCT
easat-4052	206	54	,	,	PUNCT
easat-4052	206	55	and	and	CCONJ
easat-4052	206	56	fibrin	fibrin	NOUN
easat-4052	206	57	gel	gel	NOUN
easat-4052	207	1	[	[	X
easat-4052	207	2	26	26	NUM
easat-4052	207	3	]	]	PUNCT
easat-4052	207	4	.	.	PUNCT
easat-4052	208	1	we	we	PRON
easat-4052	208	2	demonstrated	demonstrate	VERB
easat-4052	208	3	that	that	SCONJ
easat-4052	208	4	collagen	collagen	NOUN
easat-4052	208	5	,	,	PUNCT
easat-4052	208	6	ha	ha	INTJ
easat-4052	208	7	,	,	PUNCT
easat-4052	208	8	and	and	CCONJ
easat-4052	208	9	plga	plga	NOUN
easat-4052	208	10	-	-	PUNCT
easat-4052	208	11	based	base	VERB
easat-4052	208	12	scaffolds	scaffold	NOUN
easat-4052	208	13	are	be	AUX
easat-4052	208	14	among	among	ADP
easat-4052	208	15	the	the	DET
easat-4052	208	16	most	most	ADV
easat-4052	208	17	commonly	commonly	ADV
easat-4052	208	18	used	use	VERB
easat-4052	208	19	and	and	CCONJ
easat-4052	208	20	effective	effective	ADJ
easat-4052	208	21	materials	material	NOUN
easat-4052	208	22	for	for	ADP
easat-4052	208	23	knee	knee	NOUN
easat-4052	208	24	joint	joint	ADJ
easat-4052	208	25	cartilage	cartilage	NOUN
easat-4052	208	26	defects	defect	NOUN
easat-4052	208	27	due	due	ADJ
easat-4052	208	28	to	to	ADP
easat-4052	208	29	their	their	PRON
easat-4052	208	30	biocompatibility	biocompatibility	NOUN
easat-4052	208	31	,	,	PUNCT
easat-4052	208	32	ability	ability	NOUN
easat-4052	208	33	to	to	PART
easat-4052	208	34	support	support	VERB
easat-4052	208	35	cell	cell	NOUN
easat-4052	208	36	differentiation	differentiation	NOUN
easat-4052	208	37	,	,	PUNCT
easat-4052	208	38	and	and	CCONJ
easat-4052	208	39	ability	ability	NOUN
easat-4052	208	40	to	to	PART
easat-4052	208	41	mimic	mimic	VERB
easat-4052	208	42	the	the	DET
easat-4052	208	43	properties	property	NOUN
easat-4052	208	44	of	of	ADP
easat-4052	208	45	cartilage	cartilage	NOUN
easat-4052	208	46	[	[	X
easat-4052	208	47	20–23	20–23	NOUN
easat-4052	208	48	]	]	PUNCT
easat-4052	208	49	.	.	PUNCT
easat-4052	209	1	recent	recent	ADJ
easat-4052	209	2	advances	advance	NOUN
easat-4052	209	3	in	in	ADP
easat-4052	209	4	biomaterials	biomaterial	NOUN
easat-4052	209	5	and	and	CCONJ
easat-4052	209	6	fabrication	fabrication	NOUN
easat-4052	209	7	techniques	technique	NOUN
easat-4052	209	8	have	have	AUX
easat-4052	209	9	opened	open	VERB
easat-4052	209	10	new	new	ADJ
easat-4052	209	11	avenues	avenue	NOUN
easat-4052	209	12	for	for	ADP
easat-4052	209	13	the	the	DET
easat-4052	209	14	development	development	NOUN
easat-4052	209	15	of	of	ADP
easat-4052	209	16	biomimetic	biomimetic	ADJ
easat-4052	209	17	and	and	CCONJ
easat-4052	209	18	highly	highly	ADV
easat-4052	209	19	sophisticated	sophisticated	ADJ
easat-4052	209	20	scaffolds	scaffold	NOUN
easat-4052	209	21	,	,	PUNCT
easat-4052	209	22	which	which	PRON
easat-4052	209	23	can	can	AUX
easat-4052	209	24	be	be	AUX
easat-4052	209	25	categorized	categorize	VERB
easat-4052	209	26	into	into	ADP
easat-4052	209	27	monophasic	monophasic	NOUN
easat-4052	209	28	,	,	PUNCT
easat-4052	209	29	biphasic	biphasic	ADJ
easat-4052	209	30	,	,	PUNCT
easat-4052	209	31	and	and	CCONJ
easat-4052	209	32	multiphasic	multiphasic	NOUN
easat-4052	209	33	constructs	construct	NOUN
easat-4052	209	34	.	.	PUNCT
easat-4052	210	1	notably	notably	ADV
easat-4052	210	2	,	,	PUNCT
easat-4052	210	3	multiphasic	multiphasic	NOUN
easat-4052	210	4	scaffolds	scaffold	NOUN
easat-4052	210	5	offer	offer	VERB
easat-4052	210	6	several	several	ADJ
easat-4052	210	7	advantages	advantage	NOUN
easat-4052	210	8	in	in	ADP
easat-4052	210	9	terms	term	NOUN
easat-4052	210	10	of	of	ADP
easat-4052	210	11	bionic	bionic	ADJ
easat-4052	210	12	performance	performance	NOUN
easat-4052	210	13	when	when	SCONJ
easat-4052	210	14	compared	compare	VERB
easat-4052	210	15	to	to	ADP
easat-4052	210	16	monophasic	monophasic	ADJ
easat-4052	210	17	scaffolds	scaffold	NOUN
easat-4052	210	18	.	.	PUNCT
easat-4052	211	1	these	these	DET
easat-4052	211	2	advantages	advantage	NOUN
easat-4052	211	3	are	be	AUX
easat-4052	211	4	particularly	particularly	ADV
easat-4052	211	5	evident	evident	ADJ
easat-4052	211	6	in	in	ADP
easat-4052	211	7	applications	application	NOUN
easat-4052	211	8	that	that	PRON
easat-4052	211	9	require	require	VERB
easat-4052	211	10	complex	complex	ADJ
easat-4052	211	11	tissue	tissue	NOUN
easat-4052	211	12	structures	structure	NOUN
easat-4052	211	13	,	,	PUNCT
easat-4052	211	14	such	such	ADJ
easat-4052	211	15	as	as	ADP
easat-4052	211	16	oc	oc	ADP
easat-4052	211	17	repair	repair	NOUN
easat-4052	211	18	,	,	PUNCT
easat-4052	211	19	where	where	SCONJ
easat-4052	211	20	the	the	DET
easat-4052	211	21	scaffold	scaffold	NOUN
easat-4052	211	22	can	can	AUX
easat-4052	211	23	mimic	mimic	VERB
easat-4052	211	24	the	the	DET
easat-4052	211	25	distinct	distinct	ADJ
easat-4052	211	26	properties	property	NOUN
easat-4052	211	27	of	of	ADP
easat-4052	211	28	bone	bone	NOUN
easat-4052	211	29	and	and	CCONJ
easat-4052	211	30	cartilage	cartilage	NOUN
easat-4052	211	31	in	in	ADP
easat-4052	211	32	a	a	DET
easat-4052	211	33	single	single	ADJ
easat-4052	211	34	construct	construct	NOUN
easat-4052	211	35	[	[	X
easat-4052	211	36	37	37	NUM
easat-4052	211	37	]	]	PUNCT
easat-4052	211	38	.	.	PUNCT
easat-4052	212	1	the	the	DET
easat-4052	212	2	size	size	NOUN
easat-4052	212	3	,	,	PUNCT
easat-4052	212	4	location	location	NOUN
easat-4052	212	5	,	,	PUNCT
easat-4052	212	6	and	and	CCONJ
easat-4052	212	7	degree	degree	NOUN
easat-4052	212	8	of	of	ADP
easat-4052	212	9	cartilage	cartilage	NOUN
easat-4052	212	10	degeneration	degeneration	NOUN
easat-4052	212	11	of	of	ADP
easat-4052	212	12	the	the	DET
easat-4052	212	13	defect	defect	NOUN
easat-4052	212	14	all	all	DET
easat-4052	212	15	influence	influence	NOUN
easat-4052	212	16	the	the	DET
easat-4052	212	17	best	good	ADJ
easat-4052	212	18	scaffold	scaffold	NOUN
easat-4052	212	19	for	for	ADP
easat-4052	212	20	admscs	admscs	NOUN
easat-4052	212	21	to	to	PART
easat-4052	212	22	use	use	VERB
easat-4052	212	23	in	in	ADP
easat-4052	212	24	knee	knee	NOUN
easat-4052	212	25	cartilage	cartilage	NOUN
easat-4052	212	26	joint	joint	ADJ
easat-4052	212	27	defect	defect	NOUN
easat-4052	212	28	repair	repair	NOUN
easat-4052	212	29	.	.	PUNCT
easat-4052	213	1	nevertheless	nevertheless	ADV
easat-4052	213	2	,	,	PUNCT
easat-4052	213	3	the	the	DET
easat-4052	213	4	most	most	ADV
easat-4052	213	5	promising	promising	ADJ
easat-4052	213	6	alternatives	alternative	NOUN
easat-4052	213	7	are	be	AUX
easat-4052	213	8	thought	think	VERB
easat-4052	213	9	to	to	PART
easat-4052	213	10	be	be	AUX
easat-4052	213	11	hydrogel	hydrogel	NOUN
easat-4052	213	12	-	-	PUNCT
easat-4052	213	13	based	base	VERB
easat-4052	213	14	scaffolds	scaffold	NOUN
easat-4052	213	15	,	,	PUNCT
easat-4052	213	16	collagen	collagen	NOUN
easat-4052	213	17	-	-	PUNCT
easat-4052	213	18	based	base	VERB
easat-4052	213	19	scaffolds	scaffold	NOUN
easat-4052	213	20	,	,	PUNCT
easat-4052	213	21	and	and	CCONJ
easat-4052	213	22	biphasic	biphasic	ADJ
easat-4052	213	23	/	/	SYM
easat-4052	213	24	multiphasic	multiphasic	NOUN
easat-4052	213	25	scaffolds	scaffold	NOUN
easat-4052	213	26	(	(	PUNCT
easat-4052	213	27	particularly	particularly	ADV
easat-4052	213	28	for	for	ADP
easat-4052	213	29	oc	oc	ADP
easat-4052	213	30	defects	defect	NOUN
easat-4052	213	31	)	)	PUNCT
easat-4052	213	32	.	.	PUNCT
easat-4052	214	1	the	the	DET
easat-4052	214	2	ability	ability	NOUN
easat-4052	214	3	of	of	ADP
easat-4052	214	4	these	these	DET
easat-4052	214	5	scaffolds	scaffold	NOUN
easat-4052	214	6	to	to	PART
easat-4052	214	7	promote	promote	VERB
easat-4052	214	8	admsc	admsc	NOUN
easat-4052	214	9	differentiation	differentiation	NOUN
easat-4052	214	10	into	into	ADP
easat-4052	214	11	cartilage	cartilage	NOUN
easat-4052	214	12	and	and	CCONJ
easat-4052	214	13	offer	offer	VERB
easat-4052	214	14	the	the	DET
easat-4052	214	15	required	require	VERB
easat-4052	214	16	mechanical	mechanical	ADJ
easat-4052	214	17	support	support	NOUN
easat-4052	214	18	for	for	ADP
easat-4052	214	19	tissue	tissue	NOUN
easat-4052	214	20	regeneration	regeneration	NOUN
easat-4052	214	21	accounts	account	NOUN
easat-4052	214	22	for	for	ADP
easat-4052	214	23	their	their	PRON
easat-4052	214	24	effectiveness	effectiveness	NOUN
easat-4052	214	25	[	[	X
easat-4052	214	26	23,38	23,38	X
easat-4052	214	27	]	]	X
easat-4052	214	28	.	.	PUNCT
easat-4052	215	1	the	the	DET
easat-4052	215	2	role	role	NOUN
easat-4052	215	3	of	of	ADP
easat-4052	215	4	bioactive	bioactive	ADJ
easat-4052	215	5	molecules	molecule	NOUN
easat-4052	215	6	in	in	ADP
easat-4052	215	7	this	this	DET
easat-4052	215	8	context	context	NOUN
easat-4052	215	9	is	be	AUX
easat-4052	215	10	crucial	crucial	ADJ
easat-4052	215	11	for	for	ADP
easat-4052	215	12	guiding	guide	VERB
easat-4052	215	13	tissue	tissue	NOUN
easat-4052	215	14	regeneration	regeneration	NOUN
easat-4052	215	15	.	.	PUNCT
easat-4052	216	1	growth	growth	NOUN
easat-4052	216	2	factors	factor	NOUN
easat-4052	216	3	such	such	ADJ
easat-4052	216	4	as	as	ADP
easat-4052	216	5	tgf	tgf	PROPN
easat-4052	216	6	-	-	PUNCT
easat-4052	216	7	β	β	PROPN
easat-4052	216	8	,	,	PUNCT
easat-4052	216	9	bmps	bmp	NOUN
easat-4052	216	10	,	,	PUNCT
easat-4052	216	11	and	and	CCONJ
easat-4052	216	12	igf	igf	PROPN
easat-4052	216	13	stimulate	stimulate	VERB
easat-4052	216	14	the	the	DET
easat-4052	216	15	differentiation	differentiation	NOUN
easat-4052	216	16	of	of	ADP
easat-4052	216	17	stem	stem	NOUN
easat-4052	216	18	cells	cell	NOUN
easat-4052	216	19	into	into	ADP
easat-4052	216	20	cartilageproducing	cartilageproduce	VERB
easat-4052	216	21	chondrocytes	chondrocyte	NOUN
easat-4052	216	22	,	,	PUNCT
easat-4052	216	23	as	as	ADV
easat-4052	216	24	well	well	ADV
easat-4052	216	25	as	as	ADP
easat-4052	216	26	the	the	DET
easat-4052	216	27	synthesis	synthesis	NOUN
easat-4052	216	28	of	of	ADP
easat-4052	216	29	key	key	ADJ
easat-4052	216	30	ecm	ecm	NOUN
easat-4052	216	31	components	component	NOUN
easat-4052	216	32	like	like	ADP
easat-4052	216	33	collagen	collagen	NOUN
easat-4052	216	34	type	type	PROPN
easat-4052	216	35	ii	ii	PROPN
easat-4052	216	36	and	and	CCONJ
easat-4052	216	37	proteoglycans	proteoglycan	NOUN
easat-4052	216	38	,	,	PUNCT
easat-4052	216	39	which	which	PRON
easat-4052	216	40	are	be	AUX
easat-4052	216	41	vital	vital	ADJ
easat-4052	216	42	for	for	ADP
easat-4052	216	43	cartilage	cartilage	NOUN
easat-4052	216	44	integrity	integrity	NOUN
easat-4052	216	45	.	.	PUNCT
easat-4052	217	1	additionally	additionally	ADV
easat-4052	217	2	,	,	PUNCT
easat-4052	217	3	cytokines	cytokine	NOUN
easat-4052	217	4	such	such	ADJ
easat-4052	217	5	as	as	ADP
easat-4052	217	6	pdgf	pdgf	NOUN
easat-4052	217	7	(	(	PUNCT
easat-4052	217	8	plateletderived	plateletderive	VERB
easat-4052	217	9	growth	growth	NOUN
easat-4052	217	10	factor	factor	NOUN
easat-4052	217	11	)	)	PUNCT
easat-4052	217	12	and	and	CCONJ
easat-4052	217	13	fgf	fgf	PROPN
easat-4052	217	14	are	be	AUX
easat-4052	217	15	involved	involve	VERB
easat-4052	217	16	in	in	ADP
easat-4052	217	17	the	the	DET
easat-4052	217	18	recruitment	recruitment	NOUN
easat-4052	217	19	and	and	CCONJ
easat-4052	217	20	proliferation	proliferation	NOUN
easat-4052	217	21	of	of	ADP
easat-4052	217	22	cells	cell	NOUN
easat-4052	217	23	at	at	ADP
easat-4052	217	24	the	the	DET
easat-4052	217	25	injury	injury	NOUN
easat-4052	217	26	site	site	NOUN
easat-4052	217	27	,	,	PUNCT
easat-4052	217	28	promoting	promote	VERB
easat-4052	217	29	tissue	tissue	NOUN
easat-4052	217	30	repair	repair	NOUN
easat-4052	217	31	.	.	PUNCT
easat-4052	218	1	these	these	DET
easat-4052	218	2	molecules	molecule	NOUN
easat-4052	218	3	also	also	ADV
easat-4052	218	4	regulate	regulate	VERB
easat-4052	218	5	the	the	DET
easat-4052	218	6	inflammatory	inflammatory	ADJ
easat-4052	218	7	response	response	NOUN
easat-4052	218	8	,	,	PUNCT
easat-4052	218	9	creating	create	VERB
easat-4052	218	10	a	a	DET
easat-4052	218	11	favorable	favorable	ADJ
easat-4052	218	12	environment	environment	NOUN
easat-4052	218	13	for	for	ADP
easat-4052	218	14	healing	healing	NOUN
easat-4052	218	15	[	[	X
easat-4052	218	16	37,39,40	37,39,40	NUM
easat-4052	218	17	]	]	X
easat-4052	218	18	.	.	PUNCT
easat-4052	219	1	scaffold	scaffold	NOUN
easat-4052	219	2	functionalization	functionalization	NOUN
easat-4052	219	3	refers	refer	VERB
easat-4052	219	4	to	to	ADP
easat-4052	219	5	the	the	DET
easat-4052	219	6	modification	modification	NOUN
easat-4052	219	7	of	of	ADP
easat-4052	219	8	scaffold	scaffold	NOUN
easat-4052	219	9	materials	material	NOUN
easat-4052	219	10	to	to	PART
easat-4052	219	11	incorporate	incorporate	VERB
easat-4052	219	12	bioactive	bioactive	ADJ
easat-4052	219	13	molecules	molecule	NOUN
easat-4052	219	14	that	that	PRON
easat-4052	219	15	influence	influence	VERB
easat-4052	219	16	cellular	cellular	ADJ
easat-4052	219	17	behavior	behavior	NOUN
easat-4052	219	18	more	more	ADV
easat-4052	219	19	effectively	effectively	ADV
easat-4052	219	20	.	.	PUNCT
easat-4052	220	1	methods	method	NOUN
easat-4052	220	2	such	such	ADJ
easat-4052	220	3	as	as	ADP
easat-4052	220	4	physical	physical	ADJ
easat-4052	220	5	adsorption	adsorption	NOUN
easat-4052	220	6	,	,	PUNCT
easat-4052	220	7	covalent	covalent	NOUN
easat-4052	220	8	binding	binding	NOUN
easat-4052	220	9	,	,	PUNCT
easat-4052	220	10	and	and	CCONJ
easat-4052	220	11	encapsulation	encapsulation	NOUN
easat-4052	220	12	can	can	AUX
easat-4052	220	13	be	be	AUX
easat-4052	220	14	used	use	VERB
easat-4052	220	15	to	to	PART
easat-4052	220	16	integrate	integrate	VERB
easat-4052	220	17	growth	growth	NOUN
easat-4052	220	18	factors	factor	NOUN
easat-4052	220	19	and	and	CCONJ
easat-4052	220	20	cytokines	cytokine	NOUN
easat-4052	220	21	into	into	ADP
easat-4052	220	22	the	the	DET
easat-4052	220	23	scaffold	scaffold	NOUN
easat-4052	220	24	.	.	PUNCT
easat-4052	221	1	encapsulation	encapsulation	NOUN
easat-4052	221	2	,	,	PUNCT
easat-4052	221	3	in	in	ADP
easat-4052	221	4	particular	particular	ADJ
easat-4052	221	5	,	,	PUNCT
easat-4052	221	6	offers	offer	VERB
easat-4052	221	7	the	the	DET
easat-4052	221	8	advantage	advantage	NOUN
easat-4052	221	9	of	of	ADP
easat-4052	221	10	controlling	control	VERB
easat-4052	221	11	the	the	DET
easat-4052	221	12	sustained	sustained	ADJ
easat-4052	221	13	release	release	NOUN
easat-4052	221	14	of	of	ADP
easat-4052	221	15	bioactive	bioactive	ADJ
easat-4052	221	16	molecules	molecule	NOUN
easat-4052	221	17	over	over	ADP
easat-4052	221	18	time	time	NOUN
easat-4052	221	19	,	,	PUNCT
easat-4052	221	20	which	which	PRON
easat-4052	221	21	is	be	AUX
easat-4052	221	22	important	important	ADJ
easat-4052	221	23	for	for	ADP
easat-4052	221	24	long	long	ADJ
easat-4052	221	25	-	-	PUNCT
easat-4052	221	26	term	term	NOUN
easat-4052	221	27	tissue	tissue	NOUN
easat-4052	221	28	regeneration	regeneration	NOUN
easat-4052	221	29	.	.	PUNCT
easat-4052	222	1	coating	coat	VERB
easat-4052	222	2	the	the	DET
easat-4052	222	3	scaffold	scaffold	NOUN
easat-4052	222	4	with	with	ADP
easat-4052	222	5	ecm	ecm	NOUN
easat-4052	222	6	proteins	protein	NOUN
easat-4052	222	7	like	like	ADP
easat-4052	222	8	fibronectin	fibronectin	NOUN
easat-4052	222	9	or	or	CCONJ
easat-4052	222	10	collagen	collagen	NOUN
easat-4052	222	11	further	far	ADV
easat-4052	222	12	enhances	enhance	VERB
easat-4052	222	13	cell	cell	NOUN
easat-4052	222	14	attachment	attachment	NOUN
easat-4052	222	15	and	and	CCONJ
easat-4052	222	16	differentiation	differentiation	NOUN
easat-4052	222	17	,	,	PUNCT
easat-4052	222	18	ensuring	ensure	VERB
easat-4052	222	19	the	the	DET
easat-4052	222	20	scaffold	scaffold	NOUN
easat-4052	222	21	provides	provide	VERB
easat-4052	222	22	a	a	DET
easat-4052	222	23	more	more	ADV
easat-4052	222	24	natural	natural	ADJ
easat-4052	222	25	environment	environment	NOUN
easat-4052	222	26	for	for	ADP
easat-4052	222	27	cartilage	cartilage	NOUN
easat-4052	222	28	regeneration	regeneration	NOUN
easat-4052	222	29	[	[	X
easat-4052	222	30	41	41	NUM
easat-4052	222	31	]	]	PUNCT
easat-4052	222	32	.	.	PUNCT
easat-4052	223	1	once	once	ADV
easat-4052	223	2	admscs	admsc	NOUN
easat-4052	223	3	are	be	AUX
easat-4052	223	4	seeded	seed	VERB
easat-4052	223	5	onto	onto	ADP
easat-4052	223	6	the	the	DET
easat-4052	223	7	functionalized	functionalized	ADJ
easat-4052	223	8	scaffold	scaffold	NOUN
easat-4052	223	9	,	,	PUNCT
easat-4052	223	10	the	the	DET
easat-4052	223	11	bioactive	bioactive	ADJ
easat-4052	223	12	molecules	molecule	NOUN
easat-4052	223	13	guide	guide	VERB
easat-4052	223	14	the	the	DET
easat-4052	223	15	cells	cell	NOUN
easat-4052	223	16	through	through	ADP
easat-4052	223	17	the	the	DET
easat-4052	223	18	process	process	NOUN
easat-4052	223	19	of	of	ADP
easat-4052	223	20	chondrogenesis	chondrogenesis	NOUN
easat-4052	223	21	(	(	PUNCT
easat-4052	223	22	cartilage	cartilage	NOUN
easat-4052	223	23	formation	formation	NOUN
easat-4052	223	24	)	)	PUNCT
easat-4052	223	25	,	,	PUNCT
easat-4052	223	26	stimulating	stimulate	VERB
easat-4052	223	27	matrix	matrix	NOUN
easat-4052	223	28	production	production	NOUN
easat-4052	223	29	and	and	CCONJ
easat-4052	223	30	facilitating	facilitate	VERB
easat-4052	223	31	tissue	tissue	NOUN
easat-4052	223	32	regeneration	regeneration	NOUN
easat-4052	223	33	.	.	PUNCT
easat-4052	224	1	the	the	DET
easat-4052	224	2	scaffold	scaffold	NOUN
easat-4052	224	3	not	not	PART
easat-4052	224	4	only	only	ADV
easat-4052	224	5	serves	serve	VERB
easat-4052	224	6	as	as	ADP
easat-4052	224	7	a	a	DET
easat-4052	224	8	mechanical	mechanical	ADJ
easat-4052	224	9	support	support	NOUN
easat-4052	224	10	for	for	ADP
easat-4052	224	11	the	the	DET
easat-4052	224	12	cells	cell	NOUN
easat-4052	224	13	but	but	CCONJ
easat-4052	224	14	also	also	ADV
easat-4052	224	15	provides	provide	VERB
easat-4052	224	16	the	the	DET
easat-4052	224	17	necessary	necessary	ADJ
easat-4052	224	18	biochemical	biochemical	ADJ
easat-4052	224	19	signals	signal	NOUN
easat-4052	224	20	to	to	PART
easat-4052	224	21	promote	promote	VERB
easat-4052	224	22	cartilage	cartilage	NOUN
easat-4052	224	23	regeneration	regeneration	NOUN
easat-4052	224	24	[	[	X
easat-4052	224	25	41	41	NUM
easat-4052	224	26	]	]	PUNCT
easat-4052	224	27	.	.	PUNCT
easat-4052	225	1	this	this	DET
easat-4052	225	2	approach	approach	NOUN
easat-4052	225	3	has	have	AUX
easat-4052	225	4	demonstrated	demonstrate	VERB
easat-4052	225	5	potential	potential	NOUN
easat-4052	225	6	in	in	ADP
easat-4052	225	7	preclinical	preclinical	ADJ
easat-4052	225	8	and	and	CCONJ
easat-4052	225	9	clinical	clinical	ADJ
easat-4052	225	10	studies	study	NOUN
easat-4052	225	11	,	,	PUNCT
easat-4052	225	12	offering	offer	VERB
easat-4052	225	13	improvements	improvement	NOUN
easat-4052	225	14	in	in	ADP
easat-4052	225	15	cartilage	cartilage	NOUN
easat-4052	225	16	repair	repair	NOUN
easat-4052	225	17	and	and	CCONJ
easat-4052	225	18	reducing	reduce	VERB
easat-4052	225	19	the	the	DET
easat-4052	225	20	need	need	NOUN
easat-4052	225	21	for	for	ADP
easat-4052	225	22	invasive	invasive	ADJ
easat-4052	225	23	procedures	procedure	NOUN
easat-4052	225	24	such	such	ADJ
easat-4052	225	25	as	as	ADP
easat-4052	225	26	knee	knee	NOUN
easat-4052	225	27	replacements	replacement	NOUN
easat-4052	225	28	[	[	X
easat-4052	225	29	20–23	20–23	NOUN
easat-4052	225	30	]	]	PUNCT
easat-4052	225	31	.	.	PUNCT
easat-4052	226	1	this	this	DET
easat-4052	226	2	method	method	NOUN
easat-4052	226	3	has	have	VERB
easat-4052	226	4	significant	significant	ADJ
easat-4052	226	5	implications	implication	NOUN
easat-4052	226	6	for	for	ADP
easat-4052	226	7	clinical	clinical	ADJ
easat-4052	226	8	applications	application	NOUN
easat-4052	226	9	,	,	PUNCT
easat-4052	226	10	offering	offer	VERB
easat-4052	226	11	the	the	DET
easat-4052	226	12	possibility	possibility	NOUN
easat-4052	226	13	of	of	ADP
easat-4052	226	14	effective	effective	ADJ
easat-4052	226	15	repair	repair	NOUN
easat-4052	226	16	of	of	ADP
easat-4052	226	17	cartilage	cartilage	NOUN
easat-4052	226	18	defects	defect	NOUN
easat-4052	226	19	in	in	ADP
easat-4052	226	20	the	the	DET
easat-4052	226	21	knee	knee	NOUN
easat-4052	226	22	joint	joint	NOUN
easat-4052	226	23	,	,	PUNCT
easat-4052	226	24	enhancing	enhance	VERB
easat-4052	226	25	joint	joint	ADJ
easat-4052	226	26	function	function	NOUN
easat-4052	226	27	,	,	PUNCT
easat-4052	226	28	and	and	CCONJ
easat-4052	226	29	potentially	potentially	ADV
easat-4052	226	30	preventing	prevent	VERB
easat-4052	226	31	the	the	DET
easat-4052	226	32	progression	progression	NOUN
easat-4052	226	33	of	of	ADP
easat-4052	226	34	degenerative	degenerative	ADJ
easat-4052	226	35	conditions	condition	NOUN
easat-4052	226	36	like	like	ADP
easat-4052	226	37	osteoarthritis	osteoarthritis	NOUN
easat-4052	226	38	.	.	PUNCT
easat-4052	227	1	the	the	DET
easat-4052	227	2	combination	combination	NOUN
easat-4052	227	3	of	of	ADP
easat-4052	227	4	admscs	admsc	NOUN
easat-4052	227	5	,	,	PUNCT
easat-4052	227	6	bioactive	bioactive	ADJ
easat-4052	227	7	molecules	molecule	NOUN
easat-4052	227	8	,	,	PUNCT
easat-4052	227	9	and	and	CCONJ
easat-4052	227	10	scaffold	scaffold	NOUN
easat-4052	227	11	technology	technology	NOUN
easat-4052	227	12	presents	present	VERB
easat-4052	227	13	a	a	DET
easat-4052	227	14	promising	promising	ADJ
easat-4052	227	15	approach	approach	NOUN
easat-4052	227	16	to	to	ADP
easat-4052	227	17	improving	improve	VERB
easat-4052	227	18	cartilage	cartilage	NOUN
easat-4052	227	19	regeneration	regeneration	NOUN
easat-4052	227	20	and	and	CCONJ
easat-4052	227	21	providing	provide	VERB
easat-4052	227	22	an	an	DET
easat-4052	227	23	alternative	alternative	NOUN
easat-4052	227	24	to	to	ADP
easat-4052	227	25	conventional	conventional	ADJ
easat-4052	227	26	treatment	treatment	NOUN
easat-4052	227	27	options	option	NOUN
easat-4052	227	28	for	for	ADP
easat-4052	227	29	knee	knee	NOUN
easat-4052	227	30	joint	joint	ADJ
easat-4052	227	31	injuries	injury	NOUN
easat-4052	227	32	[	[	X
easat-4052	227	33	14	14	NUM
easat-4052	227	34	]	]	PUNCT
easat-4052	227	35	.	.	PUNCT
easat-4052	228	1	9602	9602	NUM
easat-4052	228	2	edelweiss	edelweiss	PROPN
easat-4052	228	3	applied	apply	VERB
easat-4052	228	4	science	science	NOUN
easat-4052	228	5	and	and	CCONJ
easat-4052	228	6	technology	technology	NOUN
easat-4052	228	7	issn	issn	PROPN
easat-4052	228	8	:	:	PUNCT
easat-4052	228	9	2576	2576	NUM
easat-4052	228	10	-	-	SYM
easat-4052	228	11	8484	8484	NUM
easat-4052	228	12	vol	vol	NOUN
easat-4052	228	13	.	.	PROPN
easat-4052	228	14	8	8	NUM
easat-4052	228	15	,	,	PUNCT
easat-4052	228	16	no	no	INTJ
easat-4052	228	17	.	.	NOUN
easat-4052	229	1	6	6	NUM
easat-4052	229	2	:	:	SYM
easat-4052	229	3	9592	9592	NUM
easat-4052	229	4	-	-	SYM
easat-4052	229	5	9604	9604	NUM
easat-4052	229	6	,	,	PUNCT
easat-4052	229	7	2024	2024	NUM
easat-4052	229	8	doi	doi	NOUN
easat-4052	229	9	:	:	PUNCT
easat-4052	229	10	10.55214/25768484.v8i6.4052	10.55214/25768484.v8i6.4052	NUM
easat-4052	230	1	©	©	ADP
easat-4052	230	2	2024	2024	NUM
easat-4052	230	3	by	by	ADP
easat-4052	230	4	the	the	DET
easat-4052	230	5	authors	author	NOUN
easat-4052	230	6	;	;	PUNCT
easat-4052	230	7	licensee	licensee	PROPN
easat-4052	230	8	learning	learning	NOUN
easat-4052	230	9	gate	gate	VERB
easat-4052	230	10	4.5	4.5	NUM
easat-4052	230	11	.	.	PUNCT
easat-4052	231	1	challenges	challenge	NOUN
easat-4052	231	2	and	and	CCONJ
easat-4052	231	3	future	future	ADJ
easat-4052	231	4	directions	direction	NOUN
easat-4052	231	5	the	the	DET
easat-4052	231	6	application	application	NOUN
easat-4052	231	7	of	of	ADP
easat-4052	231	8	scaffolds	scaffold	NOUN
easat-4052	231	9	with	with	ADP
easat-4052	231	10	admscs	admscs	NOUN
easat-4052	231	11	for	for	ADP
easat-4052	231	12	the	the	DET
easat-4052	231	13	repair	repair	NOUN
easat-4052	231	14	of	of	ADP
easat-4052	231	15	knee	knee	NOUN
easat-4052	231	16	joint	joint	ADJ
easat-4052	231	17	cartilage	cartilage	NOUN
easat-4052	231	18	defects	defect	NOUN
easat-4052	231	19	presents	present	VERB
easat-4052	231	20	several	several	ADJ
easat-4052	231	21	challenges	challenge	NOUN
easat-4052	231	22	,	,	PUNCT
easat-4052	231	23	particularly	particularly	ADV
easat-4052	231	24	in	in	ADP
easat-4052	231	25	achieving	achieve	VERB
easat-4052	231	26	optimal	optimal	ADJ
easat-4052	231	27	cell	cell	NOUN
easat-4052	231	28	survival	survival	NOUN
easat-4052	231	29	,	,	PUNCT
easat-4052	231	30	differentiation	differentiation	NOUN
easat-4052	231	31	,	,	PUNCT
easat-4052	231	32	and	and	CCONJ
easat-4052	231	33	integration	integration	NOUN
easat-4052	231	34	within	within	ADP
easat-4052	231	35	the	the	DET
easat-4052	231	36	scaffold	scaffold	NOUN
easat-4052	231	37	.	.	PUNCT
easat-4052	232	1	despite	despite	SCONJ
easat-4052	232	2	the	the	DET
easat-4052	232	3	potential	potential	NOUN
easat-4052	232	4	of	of	ADP
easat-4052	232	5	admscs	admscs	NOUN
easat-4052	232	6	to	to	PART
easat-4052	232	7	promote	promote	VERB
easat-4052	232	8	chondrogenesis	chondrogenesis	NOUN
easat-4052	232	9	,	,	PUNCT
easat-4052	232	10	the	the	DET
easat-4052	232	11	efficiency	efficiency	NOUN
easat-4052	232	12	of	of	ADP
easat-4052	232	13	cartilage	cartilage	NOUN
easat-4052	232	14	formation	formation	NOUN
easat-4052	232	15	in	in	ADP
easat-4052	232	16	vivo	vivo	NOUN
easat-4052	232	17	remains	remain	VERB
easat-4052	232	18	suboptimal	suboptimal	ADJ
easat-4052	232	19	due	due	ADP
easat-4052	232	20	to	to	ADP
easat-4052	232	21	factors	factor	NOUN
easat-4052	232	22	such	such	ADJ
easat-4052	232	23	as	as	ADP
easat-4052	232	24	the	the	DET
easat-4052	232	25	mechanical	mechanical	ADJ
easat-4052	232	26	properties	property	NOUN
easat-4052	232	27	of	of	ADP
easat-4052	232	28	the	the	DET
easat-4052	232	29	scaffold	scaffold	NOUN
easat-4052	232	30	,	,	PUNCT
easat-4052	232	31	insufficient	insufficient	ADJ
easat-4052	232	32	nutrient	nutrient	NOUN
easat-4052	232	33	exchange	exchange	NOUN
easat-4052	232	34	,	,	PUNCT
easat-4052	232	35	and	and	CCONJ
easat-4052	232	36	the	the	DET
easat-4052	232	37	complex	complex	ADJ
easat-4052	232	38	biological	biological	ADJ
easat-4052	232	39	environment	environment	NOUN
easat-4052	232	40	of	of	ADP
easat-4052	232	41	the	the	DET
easat-4052	232	42	joint	joint	NOUN
easat-4052	232	43	.	.	PUNCT
easat-4052	233	1	additionally	additionally	ADV
easat-4052	233	2	,	,	PUNCT
easat-4052	233	3	the	the	DET
easat-4052	233	4	controlled	control	VERB
easat-4052	233	5	delivery	delivery	NOUN
easat-4052	233	6	and	and	CCONJ
easat-4052	233	7	release	release	NOUN
easat-4052	233	8	of	of	ADP
easat-4052	233	9	bioactive	bioactive	ADJ
easat-4052	233	10	molecules	molecule	NOUN
easat-4052	233	11	,	,	PUNCT
easat-4052	233	12	including	include	VERB
easat-4052	233	13	growth	growth	NOUN
easat-4052	233	14	factors	factor	NOUN
easat-4052	233	15	and	and	CCONJ
easat-4052	233	16	cytokines	cytokine	NOUN
easat-4052	233	17	,	,	PUNCT
easat-4052	233	18	requires	require	VERB
easat-4052	233	19	precise	precise	ADJ
easat-4052	233	20	engineering	engineering	NOUN
easat-4052	233	21	to	to	PART
easat-4052	233	22	ensure	ensure	VERB
easat-4052	233	23	their	their	PRON
easat-4052	233	24	sustained	sustained	ADJ
easat-4052	233	25	and	and	CCONJ
easat-4052	233	26	localized	localized	ADJ
easat-4052	233	27	activity	activity	NOUN
easat-4052	233	28	without	without	ADP
easat-4052	233	29	causing	cause	VERB
easat-4052	233	30	adverse	adverse	ADJ
easat-4052	233	31	effects	effect	NOUN
easat-4052	233	32	like	like	ADP
easat-4052	233	33	excessive	excessive	ADJ
easat-4052	233	34	inflammation	inflammation	NOUN
easat-4052	233	35	or	or	CCONJ
easat-4052	233	36	fibrosis	fibrosis	NOUN
easat-4052	233	37	.	.	PUNCT
easat-4052	234	1	the	the	DET
easat-4052	234	2	long	long	ADJ
easat-4052	234	3	-	-	PUNCT
easat-4052	234	4	term	term	NOUN
easat-4052	234	5	stability	stability	NOUN
easat-4052	234	6	of	of	ADP
easat-4052	234	7	the	the	DET
easat-4052	234	8	engineered	engineer	VERB
easat-4052	234	9	tissue	tissue	NOUN
easat-4052	234	10	and	and	CCONJ
easat-4052	234	11	the	the	DET
easat-4052	234	12	immune	immune	ADJ
easat-4052	234	13	response	response	NOUN
easat-4052	234	14	to	to	ADP
easat-4052	234	15	the	the	DET
easat-4052	234	16	scaffold	scaffold	NOUN
easat-4052	234	17	material	material	NOUN
easat-4052	234	18	also	also	ADV
easat-4052	234	19	represent	represent	VERB
easat-4052	234	20	significant	significant	ADJ
easat-4052	234	21	concerns	concern	NOUN
easat-4052	234	22	.	.	PUNCT
easat-4052	235	1	future	future	ADJ
easat-4052	235	2	research	research	NOUN
easat-4052	235	3	should	should	AUX
easat-4052	235	4	focus	focus	VERB
easat-4052	235	5	on	on	ADP
easat-4052	235	6	developing	develop	VERB
easat-4052	235	7	advanced	advanced	ADJ
easat-4052	235	8	scaffold	scaffold	NOUN
easat-4052	235	9	materials	material	NOUN
easat-4052	235	10	with	with	ADP
easat-4052	235	11	improved	improved	ADJ
easat-4052	235	12	biocompatibility	biocompatibility	NOUN
easat-4052	235	13	,	,	PUNCT
easat-4052	235	14	vascularization	vascularization	NOUN
easat-4052	235	15	,	,	PUNCT
easat-4052	235	16	and	and	CCONJ
easat-4052	235	17	mechanical	mechanical	ADJ
easat-4052	235	18	properties	property	NOUN
easat-4052	235	19	that	that	PRON
easat-4052	235	20	more	more	ADV
easat-4052	235	21	closely	closely	ADV
easat-4052	235	22	resemble	resemble	VERB
easat-4052	235	23	the	the	DET
easat-4052	235	24	native	native	ADJ
easat-4052	235	25	cartilage	cartilage	NOUN
easat-4052	235	26	matrix	matrix	NOUN
easat-4052	235	27	.	.	PUNCT
easat-4052	236	1	furthermore	furthermore	ADV
easat-4052	236	2	,	,	PUNCT
easat-4052	236	3	incorporating	incorporate	VERB
easat-4052	236	4	techniques	technique	NOUN
easat-4052	236	5	such	such	ADJ
easat-4052	236	6	as	as	ADP
easat-4052	236	7	gene	gene	NOUN
easat-4052	236	8	editing	editing	NOUN
easat-4052	236	9	or	or	CCONJ
easat-4052	236	10	cell	cell	NOUN
easat-4052	236	11	preconditioning	preconditioning	NOUN
easat-4052	236	12	may	may	AUX
easat-4052	236	13	enhance	enhance	VERB
easat-4052	236	14	the	the	DET
easat-4052	236	15	regenerative	regenerative	ADJ
easat-4052	236	16	potential	potential	NOUN
easat-4052	236	17	of	of	ADP
easat-4052	236	18	admscs	admsc	NOUN
easat-4052	236	19	,	,	PUNCT
easat-4052	236	20	leading	lead	VERB
easat-4052	236	21	to	to	ADP
easat-4052	236	22	more	more	ADV
easat-4052	236	23	efficient	efficient	ADJ
easat-4052	236	24	cartilage	cartilage	NOUN
easat-4052	236	25	regeneration	regeneration	NOUN
easat-4052	236	26	.	.	PUNCT
easat-4052	237	1	ultimately	ultimately	ADV
easat-4052	237	2	,	,	PUNCT
easat-4052	237	3	clinical	clinical	ADJ
easat-4052	237	4	trials	trial	NOUN
easat-4052	237	5	and	and	CCONJ
easat-4052	237	6	personalized	personalize	VERB
easat-4052	237	7	therapeutic	therapeutic	ADJ
easat-4052	237	8	approaches	approach	NOUN
easat-4052	237	9	will	will	AUX
easat-4052	237	10	be	be	AUX
easat-4052	237	11	crucial	crucial	ADJ
easat-4052	237	12	for	for	ADP
easat-4052	237	13	translating	translate	VERB
easat-4052	237	14	these	these	DET
easat-4052	237	15	technological	technological	ADJ
easat-4052	237	16	advances	advance	NOUN
easat-4052	237	17	into	into	ADP
easat-4052	237	18	effective	effective	ADJ
easat-4052	237	19	treatments	treatment	NOUN
easat-4052	237	20	for	for	ADP
easat-4052	237	21	knee	knee	NOUN
easat-4052	237	22	joint	joint	ADJ
easat-4052	237	23	cartilage	cartilage	NOUN
easat-4052	237	24	defects	defect	NOUN
easat-4052	237	25	.	.	PUNCT
easat-4052	238	1	5	5	X
easat-4052	238	2	.	.	X
easat-4052	238	3	conclusion	conclusion	NOUN
easat-4052	238	4	this	this	DET
easat-4052	238	5	literature	literature	NOUN
easat-4052	238	6	review	review	NOUN
easat-4052	238	7	highlights	highlight	VERB
easat-4052	238	8	the	the	DET
easat-4052	238	9	importance	importance	NOUN
easat-4052	238	10	of	of	ADP
easat-4052	238	11	scaffold	scaffold	NOUN
easat-4052	238	12	modality	modality	NOUN
easat-4052	238	13	with	with	ADP
easat-4052	238	14	admscs	admscs	NOUN
easat-4052	238	15	as	as	ADP
easat-4052	238	16	a	a	DET
easat-4052	238	17	regenerative	regenerative	ADJ
easat-4052	238	18	treatment	treatment	NOUN
easat-4052	238	19	for	for	ADP
easat-4052	238	20	knee	knee	NOUN
easat-4052	238	21	joint	joint	ADJ
easat-4052	238	22	cartilage	cartilage	NOUN
easat-4052	238	23	defects	defect	NOUN
easat-4052	238	24	.	.	PUNCT
easat-4052	239	1	scaffolds	scaffold	NOUN
easat-4052	239	2	serve	serve	VERB
easat-4052	239	3	as	as	ADP
easat-4052	239	4	a	a	DET
easat-4052	239	5	supportive	supportive	ADJ
easat-4052	239	6	framework	framework	NOUN
easat-4052	239	7	,	,	PUNCT
easat-4052	239	8	providing	provide	VERB
easat-4052	239	9	an	an	DET
easat-4052	239	10	ideal	ideal	ADJ
easat-4052	239	11	environment	environment	NOUN
easat-4052	239	12	for	for	SCONJ
easat-4052	239	13	admscs	admscs	NOUN
easat-4052	239	14	to	to	PART
easat-4052	239	15	proliferate	proliferate	VERB
easat-4052	239	16	,	,	PUNCT
easat-4052	239	17	differentiate	differentiate	ADJ
easat-4052	239	18	,	,	PUNCT
easat-4052	239	19	and	and	CCONJ
easat-4052	239	20	facilitate	facilitate	VERB
easat-4052	239	21	tissue	tissue	NOUN
easat-4052	239	22	regeneration	regeneration	NOUN
easat-4052	239	23	.	.	PUNCT
easat-4052	240	1	admscs	admsc	NOUN
easat-4052	240	2	,	,	PUNCT
easat-4052	240	3	through	through	ADP
easat-4052	240	4	their	their	PRON
easat-4052	240	5	paracrine	paracrine	NOUN
easat-4052	240	6	effects	effect	NOUN
easat-4052	240	7	,	,	PUNCT
easat-4052	240	8	promote	promote	VERB
easat-4052	240	9	cartilage	cartilage	NOUN
easat-4052	240	10	repair	repair	NOUN
easat-4052	240	11	by	by	ADP
easat-4052	240	12	secreting	secrete	VERB
easat-4052	240	13	factors	factor	NOUN
easat-4052	240	14	that	that	PRON
easat-4052	240	15	regulate	regulate	VERB
easat-4052	240	16	inflammation	inflammation	NOUN
easat-4052	240	17	,	,	PUNCT
easat-4052	240	18	encourage	encourage	VERB
easat-4052	240	19	chondrogenesis	chondrogenesis	NOUN
easat-4052	240	20	,	,	PUNCT
easat-4052	240	21	and	and	CCONJ
easat-4052	240	22	assist	assist	VERB
easat-4052	240	23	in	in	ADP
easat-4052	240	24	ecm	ecm	NOUN
easat-4052	240	25	remodeling	remodeling	NOUN
easat-4052	240	26	.	.	PUNCT
easat-4052	241	1	although	although	SCONJ
easat-4052	241	2	clinical	clinical	ADJ
easat-4052	241	3	results	result	NOUN
easat-4052	241	4	are	be	AUX
easat-4052	241	5	encouraging	encouraging	ADJ
easat-4052	241	6	,	,	PUNCT
easat-4052	241	7	additional	additional	ADJ
easat-4052	241	8	research	research	NOUN
easat-4052	241	9	is	be	AUX
easat-4052	241	10	required	require	VERB
easat-4052	241	11	to	to	PART
easat-4052	241	12	optimize	optimize	VERB
easat-4052	241	13	scaffold	scaffold	NOUN
easat-4052	241	14	materials	material	NOUN
easat-4052	241	15	,	,	PUNCT
easat-4052	241	16	admsc	admsc	NOUN
easat-4052	241	17	delivery	delivery	NOUN
easat-4052	241	18	techniques	technique	NOUN
easat-4052	241	19	,	,	PUNCT
easat-4052	241	20	and	and	CCONJ
easat-4052	241	21	treatment	treatment	NOUN
easat-4052	241	22	protocols	protocol	NOUN
easat-4052	241	23	.	.	PUNCT
easat-4052	242	1	collectively	collectively	ADV
easat-4052	242	2	,	,	PUNCT
easat-4052	242	3	scaffolds	scaffold	NOUN
easat-4052	242	4	and	and	CCONJ
easat-4052	242	5	admscs	admsc	NOUN
easat-4052	242	6	offer	offer	VERB
easat-4052	242	7	a	a	DET
easat-4052	242	8	valuable	valuable	ADJ
easat-4052	242	9	approach	approach	NOUN
easat-4052	242	10	to	to	ADP
easat-4052	242	11	restoring	restore	VERB
easat-4052	242	12	knee	knee	NOUN
easat-4052	242	13	cartilage	cartilage	NOUN
easat-4052	242	14	function	function	NOUN
easat-4052	242	15	and	and	CCONJ
easat-4052	242	16	advancing	advance	VERB
easat-4052	242	17	regenerative	regenerative	ADJ
easat-4052	242	18	treatments	treatment	NOUN
easat-4052	242	19	in	in	ADP
easat-4052	242	20	orthopedic	orthopedic	ADJ
easat-4052	242	21	medicine	medicine	NOUN
easat-4052	242	22	.	.	PUNCT
easat-4052	243	1	copyright	copyright	NOUN
easat-4052	243	2	:	:	PUNCT
easat-4052	243	3	©	©	PROPN
easat-4052	243	4	2024	2024	NUM
easat-4052	243	5	by	by	ADP
easat-4052	243	6	the	the	DET
easat-4052	243	7	authors	author	NOUN
easat-4052	243	8	.	.	PUNCT
easat-4052	244	1	this	this	DET
easat-4052	244	2	article	article	NOUN
easat-4052	244	3	is	be	AUX
easat-4052	244	4	an	an	DET
easat-4052	244	5	open	open	ADJ
easat-4052	244	6	access	access	NOUN
easat-4052	244	7	article	article	NOUN
easat-4052	244	8	distributed	distribute	VERB
easat-4052	244	9	under	under	ADP
easat-4052	244	10	the	the	DET
easat-4052	244	11	terms	term	NOUN
easat-4052	244	12	and	and	CCONJ
easat-4052	244	13	conditions	condition	NOUN
easat-4052	244	14	of	of	ADP
easat-4052	244	15	the	the	DET
easat-4052	244	16	creative	creative	ADJ
easat-4052	244	17	commons	common	NOUN
easat-4052	244	18	attribution	attribution	NOUN
easat-4052	244	19	(	(	PUNCT
easat-4052	244	20	cc	cc	NOUN
easat-4052	244	21	by	by	ADP
easat-4052	244	22	)	)	PUNCT
easat-4052	244	23	license	license	NOUN
easat-4052	244	24	(	(	PUNCT
easat-4052	244	25	https://creativecommons.org/licenses/by/4.0/	https://creativecommons.org/licenses/by/4.0/	PROPN
easat-4052	244	26	)	)	PUNCT
easat-4052	244	27	.	.	PUNCT
easat-4052	245	1	references	reference	NOUN
easat-4052	245	2	[	[	X
easat-4052	245	3	1	1	X
easat-4052	245	4	]	]	PUNCT
easat-4052	245	5	husen	husen	PROPN
easat-4052	245	6	m	m	PROPN
easat-4052	245	7	,	,	PUNCT
easat-4052	245	8	custers	custer	NOUN
easat-4052	245	9	rjh	rjh	PROPN
easat-4052	245	10	,	,	PUNCT
easat-4052	245	11	hevesi	hevesi	PROPN
easat-4052	245	12	m	m	PROPN
easat-4052	245	13	,	,	PUNCT
easat-4052	245	14	krych	krych	PROPN
easat-4052	245	15	aj	aj	PROPN
easat-4052	245	16	,	,	PUNCT
easat-4052	245	17	saris	saris	PROPN
easat-4052	245	18	dbf	dbf	PROPN
easat-4052	245	19	.	.	PROPN
easat-4052	245	20	size	size	NOUN
easat-4052	245	21	of	of	ADP
easat-4052	245	22	cartilage	cartilage	NOUN
easat-4052	245	23	defects	defect	NOUN
easat-4052	245	24	and	and	CCONJ
easat-4052	245	25	the	the	DET
easat-4052	245	26	need	need	NOUN
easat-4052	245	27	for	for	ADP
easat-4052	245	28	repair	repair	NOUN
easat-4052	245	29	:	:	PUNCT
easat-4052	245	30	a	a	DET
easat-4052	245	31	systematic	systematic	ADJ
easat-4052	245	32	review	review	NOUN
easat-4052	245	33	.	.	PUNCT
easat-4052	246	1	j	j	PROPN
easat-4052	246	2	cartil	cartil	PROPN
easat-4052	246	3	jt	jt	PROPN
easat-4052	246	4	preserv	preserv	NOUN
easat-4052	246	5	.	.	PUNCT
easat-4052	247	1	2022;2(3):1–16	2022;2(3):1–16	X
easat-4052	247	2	.	.	PUNCT
easat-4052	248	1	https://doi.org/10.1016/j.jcjp.2022.100049	https://doi.org/10.1016/j.jcjp.2022.100049	PROPN
easat-4052	248	2	[	[	X
easat-4052	248	3	2	2	NUM
easat-4052	248	4	]	]	PUNCT
easat-4052	248	5	jarecki	jarecki	PROPN
easat-4052	248	6	j	j	PROPN
easat-4052	248	7	,	,	PUNCT
easat-4052	248	8	waśko	waśko	PROPN
easat-4052	248	9	mk	mk	PROPN
easat-4052	248	10	,	,	PUNCT
easat-4052	248	11	widuchowski	widuchowski	ADJ
easat-4052	248	12	w	w	PROPN
easat-4052	248	13	,	,	PUNCT
easat-4052	248	14	tomczyk	tomczyk	NOUN
easat-4052	248	15	-	-	PUNCT
easat-4052	248	16	warunek	warunek	NOUN
easat-4052	248	17	a	a	PRON
easat-4052	248	18	,	,	PUNCT
easat-4052	248	19	wójciak	wójciak	PROPN
easat-4052	248	20	m	m	PROPN
easat-4052	248	21	,	,	PUNCT
easat-4052	248	22	sowa	sowa	PROPN
easat-4052	248	23	i	i	PRON
easat-4052	248	24	,	,	PUNCT
easat-4052	248	25	et	et	PROPN
easat-4052	248	26	al	al	PROPN
easat-4052	248	27	.	.	PUNCT
easat-4052	248	28	knee	knee	NOUN
easat-4052	248	29	cartilage	cartilage	NOUN
easat-4052	248	30	lesion	lesion	NOUN
easat-4052	248	31	management	management	NOUN
easat-4052	248	32	—	—	PUNCT
easat-4052	248	33	current	current	ADJ
easat-4052	248	34	trends	trend	NOUN
easat-4052	248	35	in	in	ADP
easat-4052	248	36	clinical	clinical	ADJ
easat-4052	248	37	practice	practice	NOUN
easat-4052	248	38	.	.	PUNCT
easat-4052	249	1	j	j	PROPN
easat-4052	249	2	clin	clin	PROPN
easat-4052	249	3	med	med	PROPN
easat-4052	249	4	.	.	PUNCT
easat-4052	250	1	2023;12(20):1–22	2023;12(20):1–22	NUM
easat-4052	250	2	.	.	X
easat-4052	250	3	https://doi.org/10.3390/jcm12206434	https://doi.org/10.3390/jcm12206434	PROPN
easat-4052	250	4	[	[	X
easat-4052	250	5	3	3	NUM
easat-4052	250	6	]	]	X
easat-4052	250	7	matsushita	matsushita	PROPN
easat-4052	250	8	t	t	PROPN
easat-4052	250	9	,	,	PUNCT
easat-4052	250	10	tokura	tokura	PROPN
easat-4052	250	11	t	t	PROPN
easat-4052	250	12	,	,	PUNCT
easat-4052	250	13	okimura	okimura	PROPN
easat-4052	250	14	k	k	PROPN
easat-4052	250	15	,	,	PUNCT
easat-4052	250	16	sano	sano	PROPN
easat-4052	250	17	s	s	PROPN
easat-4052	250	18	,	,	PUNCT
easat-4052	250	19	nishida	nishida	PROPN
easat-4052	250	20	k	k	PROPN
easat-4052	250	21	,	,	PUNCT
easat-4052	250	22	nagai	nagai	PROPN
easat-4052	250	23	k	k	PROPN
easat-4052	250	24	,	,	PUNCT
easat-4052	250	25	et	et	PROPN
easat-4052	250	26	al	al	PROPN
easat-4052	250	27	.	.	PUNCT
easat-4052	251	1	surgical	surgical	ADJ
easat-4052	251	2	treatment	treatment	NOUN
easat-4052	251	3	of	of	ADP
easat-4052	251	4	cartilage	cartilage	NOUN
easat-4052	251	5	lesions	lesion	NOUN
easat-4052	251	6	in	in	ADP
easat-4052	251	7	the	the	DET
easat-4052	251	8	knee	knee	NOUN
easat-4052	251	9	:	:	PUNCT
easat-4052	251	10	a	a	DET
easat-4052	251	11	narrative	narrative	NOUN
easat-4052	251	12	review	review	NOUN
easat-4052	251	13	.	.	PUNCT
easat-4052	252	1	j	j	PROPN
easat-4052	252	2	jt	jt	PROPN
easat-4052	252	3	surg	surg	PROPN
easat-4052	252	4	res	res	PROPN
easat-4052	252	5	.	.	PUNCT
easat-4052	253	1	2023;1(1):70–9	2023;1(1):70–9	NOUN
easat-4052	253	2	.	.	PUNCT
easat-4052	254	1	https://doi.org/10.1016/j.jjoisr.2023.02.001	https://doi.org/10.1016/j.jjoisr.2023.02.001	PROPN
easat-4052	255	1	[	[	X
easat-4052	255	2	4	4	NUM
easat-4052	255	3	]	]	X
easat-4052	255	4	zhao	zhao	PROPN
easat-4052	255	5	x	x	PROPN
easat-4052	255	6	,	,	PUNCT
easat-4052	255	7	hu	hu	PROPN
easat-4052	255	8	da	da	PROPN
easat-4052	255	9	,	,	PUNCT
easat-4052	255	10	wu	wu	PROPN
easat-4052	255	11	d	d	PROPN
easat-4052	255	12	,	,	PUNCT
easat-4052	255	13	he	he	PRON
easat-4052	255	14	f	f	AUX
easat-4052	255	15	,	,	PUNCT
easat-4052	255	16	wang	wang	PROPN
easat-4052	255	17	h	h	PROPN
easat-4052	255	18	,	,	PUNCT
easat-4052	255	19	huang	huang	PROPN
easat-4052	255	20	l	l	PROPN
easat-4052	255	21	,	,	PUNCT
easat-4052	255	22	et	et	PROPN
easat-4052	255	23	al	al	PROPN
easat-4052	255	24	.	.	PUNCT
easat-4052	255	25	applications	application	NOUN
easat-4052	255	26	of	of	ADP
easat-4052	255	27	biocompatible	biocompatible	ADJ
easat-4052	255	28	scaffold	scaffold	NOUN
easat-4052	255	29	materials	material	NOUN
easat-4052	255	30	in	in	ADP
easat-4052	255	31	stem	stem	NOUN
easat-4052	255	32	cell	cell	NOUN
easat-4052	255	33	-	-	PUNCT
easat-4052	255	34	based	base	VERB
easat-4052	255	35	cartilage	cartilage	NOUN
easat-4052	255	36	tissue	tissue	NOUN
easat-4052	255	37	engineering	engineering	NOUN
easat-4052	255	38	.	.	PUNCT
easat-4052	256	1	front	front	ADJ
easat-4052	256	2	bioeng	bioeng	PROPN
easat-4052	256	3	biotechnol	biotechnol	NOUN
easat-4052	256	4	.	.	PUNCT
easat-4052	257	1	2021;9(march):1–23	2021;9(march):1–23	PROPN
easat-4052	257	2	.	.	PUNCT
easat-4052	258	1	https://doi.org/10.3389/fbioe.2021.603444	https://doi.org/10.3389/fbioe.2021.603444	PROPN
easat-4052	259	1	[	[	X
easat-4052	259	2	5	5	NUM
easat-4052	259	3	]	]	PUNCT
easat-4052	259	4	plancher	plancher	PROPN
easat-4052	259	5	kd	kd	PROPN
easat-4052	259	6	,	,	PUNCT
easat-4052	259	7	agyapong	agyapong	VERB
easat-4052	259	8	g	g	PROPN
easat-4052	259	9	,	,	PUNCT
easat-4052	259	10	dows	dow	VERB
easat-4052	259	11	a	a	PRON
easat-4052	259	12	,	,	PUNCT
easat-4052	259	13	wang	wang	PROPN
easat-4052	259	14	kh	kh	PROPN
easat-4052	259	15	,	,	PUNCT
easat-4052	259	16	reyes	reyes	PROPN
easat-4052	259	17	mm	mm	PROPN
easat-4052	259	18	,	,	PUNCT
easat-4052	259	19	briggs	briggs	PROPN
easat-4052	259	20	kk	kk	PROPN
easat-4052	259	21	,	,	PUNCT
easat-4052	259	22	et	et	PROPN
easat-4052	259	23	al	al	PROPN
easat-4052	259	24	.	.	PUNCT
easat-4052	259	25	management	management	NOUN
easat-4052	259	26	of	of	ADP
easat-4052	259	27	articular	articular	ADJ
easat-4052	259	28	cartilage	cartilage	NOUN
easat-4052	259	29	defects	defect	NOUN
easat-4052	259	30	in	in	ADP
easat-4052	259	31	the	the	DET
easat-4052	259	32	knee	knee	NOUN
easat-4052	259	33	:	:	PUNCT
easat-4052	259	34	an	an	DET
easat-4052	259	35	evidence	evidence	NOUN
easat-4052	259	36	-	-	PUNCT
easat-4052	259	37	based	base	VERB
easat-4052	259	38	algorithm	algorithm	NOUN
easat-4052	259	39	.	.	PUNCT
easat-4052	260	1	jbjs	jbjs	PROPN
easat-4052	260	2	j	j	PROPN
easat-4052	260	3	orthop	orthop	PROPN
easat-4052	260	4	physician	physician	NOUN
easat-4052	260	5	assist	assist	NOUN
easat-4052	260	6	.	.	PUNCT
easat-4052	261	1	2024;12(2):e24.00004	2024;12(2):e24.00004	X
easat-4052	261	2	.	.	PUNCT
easat-4052	262	1	https://doi.org/10.2106/jbjs.jopa.24.00004	https://doi.org/10.2106/jbjs.jopa.24.00004	PROPN
easat-4052	262	2	[	[	X
easat-4052	262	3	6	6	X
easat-4052	262	4	]	]	PUNCT
easat-4052	262	5	salzmann	salzmann	PROPN
easat-4052	262	6	gm	gm	PROPN
easat-4052	262	7	,	,	PUNCT
easat-4052	262	8	niemeyer	niemeyer	PROPN
easat-4052	262	9	p	p	X
easat-4052	262	10	,	,	PUNCT
easat-4052	262	11	hochrein	hochrein	NOUN
easat-4052	262	12	a	a	PRON
easat-4052	262	13	,	,	PUNCT
easat-4052	262	14	stoddart	stoddart	PROPN
easat-4052	262	15	mj	mj	PROPN
easat-4052	262	16	,	,	PUNCT
easat-4052	262	17	angele	angele	PROPN
easat-4052	262	18	p.	p.	NOUN
easat-4052	262	19	articular	articular	ADJ
easat-4052	262	20	cartilage	cartilage	NOUN
easat-4052	262	21	repair	repair	NOUN
easat-4052	262	22	of	of	ADP
easat-4052	262	23	the	the	DET
easat-4052	262	24	knee	knee	NOUN
easat-4052	262	25	in	in	ADP
easat-4052	262	26	children	child	NOUN
easat-4052	262	27	and	and	CCONJ
easat-4052	262	28	adolescents	adolescent	NOUN
easat-4052	262	29	.	.	PUNCT
easat-4052	263	1	orthop	orthop	PROPN
easat-4052	263	2	j	j	PROPN
easat-4052	263	3	sport	sport	PROPN
easat-4052	263	4	med	me	VERB
easat-4052	263	5	.	.	PUNCT
easat-4052	264	1	2018;6(3):1–12	2018;6(3):1–12	NUM
easat-4052	264	2	.	.	PUNCT
easat-4052	265	1	https://doi.org/10.1177/2325967118760190	https://doi.org/10.1177/2325967118760190	NOUN
easat-4052	266	1	[	[	X
easat-4052	266	2	7	7	X
easat-4052	266	3	]	]	X
easat-4052	266	4	chen	chen	PROPN
easat-4052	266	5	m	m	PROPN
easat-4052	266	6	,	,	PUNCT
easat-4052	266	7	jiang	jiang	PROPN
easat-4052	266	8	z	z	PROPN
easat-4052	266	9	,	,	PUNCT
easat-4052	266	10	zou	zou	PROPN
easat-4052	266	11	x	x	PROPN
easat-4052	266	12	,	,	PUNCT
easat-4052	266	13	you	you	PRON
easat-4052	266	14	x	x	NOUN
easat-4052	266	15	,	,	PUNCT
easat-4052	266	16	cai	cai	PROPN
easat-4052	267	1	z	z	PROPN
easat-4052	267	2	,	,	PUNCT
easat-4052	267	3	huang	huang	PROPN
easat-4052	267	4	j.	j.	PROPN
easat-4052	267	5	advancements	advancements	PROPN
easat-4052	267	6	in	in	ADP
easat-4052	267	7	tissue	tissue	NOUN
easat-4052	267	8	engineering	engineering	NOUN
easat-4052	267	9	for	for	ADP
easat-4052	267	10	articular	articular	ADJ
easat-4052	267	11	cartilage	cartilage	NOUN
easat-4052	267	12	regeneration	regeneration	NOUN
easat-4052	267	13	.	.	PUNCT
easat-4052	268	1	heliyon	heliyon	NOUN
easat-4052	268	2	.	.	PUNCT
easat-4052	269	1	2024;10(3):e25400	2024;10(3):e25400	X
easat-4052	269	2	.	.	PUNCT
easat-4052	269	3	https://doi.org/10.1016/j.heliyon.2024.e25400	https://doi.org/10.1016/j.heliyon.2024.e25400	X
easat-4052	270	1	[	[	X
easat-4052	270	2	8	8	NUM
easat-4052	270	3	]	]	X
easat-4052	270	4	de	de	X
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easat-4052	270	6	a	a	PROPN
easat-4052	270	7	,	,	PUNCT
easat-4052	270	8	rochev	rochev	PROPN
easat-4052	270	9	y	y	PROPN
easat-4052	270	10	,	,	PUNCT
easat-4052	270	11	zeugolis	zeugolis	PROPN
easat-4052	270	12	di	di	PROPN
easat-4052	270	13	.	.	PUNCT
easat-4052	270	14	scaffold	scaffold	NOUN
easat-4052	270	15	-	-	PUNCT
easat-4052	270	16	free	free	ADJ
easat-4052	270	17	cell	cell	NOUN
easat-4052	270	18	-	-	PUNCT
easat-4052	270	19	based	base	VERB
easat-4052	270	20	tissue	tissue	NOUN
easat-4052	270	21	engineering	engineering	NOUN
easat-4052	270	22	therapies	therapy	NOUN
easat-4052	270	23	:	:	PUNCT
easat-4052	270	24	advances	advance	NOUN
easat-4052	270	25	,	,	PUNCT
easat-4052	270	26	shortfalls	shortfall	NOUN
easat-4052	270	27	and	and	CCONJ
easat-4052	270	28	forecast	forecast	NOUN
easat-4052	270	29	.	.	PUNCT
easat-4052	271	1	regen	regen	PROPN
easat-4052	271	2	med	med	PROPN
easat-4052	271	3	.	.	PUNCT
easat-4052	272	1	2021;6(18):1–15	2021;6(18):1–15	NUM
easat-4052	272	2	.	.	PUNCT
easat-4052	272	3	http://dx.doi.org/10.1038/s41536-021-00133-3	http://dx.doi.org/10.1038/s41536-021-00133-3	PART
easat-4052	273	1	[	[	X
easat-4052	273	2	9	9	NUM
easat-4052	273	3	]	]	X
easat-4052	273	4	guo	guo	PROPN
easat-4052	273	5	x	x	NOUN
easat-4052	273	6	,	,	PUNCT
easat-4052	273	7	xi	xi	PROPN
easat-4052	273	8	l	l	PROPN
easat-4052	273	9	,	,	PUNCT
easat-4052	273	10	yu	yu	PROPN
easat-4052	273	11	m	m	PROPN
easat-4052	273	12	,	,	PUNCT
easat-4052	273	13	fan	fan	PROPN
easat-4052	273	14	z	z	PROPN
easat-4052	273	15	,	,	PUNCT
easat-4052	273	16	wang	wang	PROPN
easat-4052	273	17	w	w	PROPN
easat-4052	273	18	,	,	PUNCT
easat-4052	273	19	ju	ju	PROPN
easat-4052	273	20	a	a	PROPN
easat-4052	273	21	,	,	PUNCT
easat-4052	273	22	et	et	PROPN
easat-4052	273	23	al	al	PROPN
easat-4052	273	24	.	.	PROPN
easat-4052	273	25	regeneration	regeneration	NOUN
easat-4052	273	26	of	of	ADP
easat-4052	273	27	articular	articular	ADJ
easat-4052	273	28	cartilage	cartilage	NOUN
easat-4052	273	29	defects	defect	NOUN
easat-4052	273	30	:	:	PUNCT
easat-4052	273	31	therapeutic	therapeutic	ADJ
easat-4052	273	32	strategies	strategy	NOUN
easat-4052	273	33	and	and	CCONJ
easat-4052	273	34	perspectives	perspective	NOUN
easat-4052	273	35	.	.	PUNCT
easat-4052	274	1	j	j	PROPN
easat-4052	274	2	tissue	tissue	NOUN
easat-4052	274	3	eng	eng	PROPN
easat-4052	274	4	.	.	PUNCT
easat-4052	275	1	2023;14(1):1–27	2023;14(1):1–27	NUM
easat-4052	275	2	.	.	PUNCT
easat-4052	275	3	https://doi.org/10.1177/20417314231164765	https://doi.org/10.1177/20417314231164765	PUNCT
easat-4052	276	1	[	[	X
easat-4052	276	2	10	10	NUM
easat-4052	276	3	]	]	PUNCT
easat-4052	276	4	cong	cong	NOUN
easat-4052	276	5	b	b	PROPN
easat-4052	276	6	,	,	PUNCT
easat-4052	276	7	sun	sun	PROPN
easat-4052	276	8	t	t	PROPN
easat-4052	276	9	,	,	PUNCT
easat-4052	276	10	zhao	zhao	PROPN
easat-4052	276	11	y	y	PROPN
easat-4052	276	12	,	,	PUNCT
easat-4052	276	13	chen	chen	PROPN
easat-4052	276	14	m.	m.	PROPN
easat-4052	276	15	current	current	ADJ
easat-4052	276	16	and	and	CCONJ
easat-4052	276	17	novel	novel	ADJ
easat-4052	276	18	therapeutics	therapeutic	NOUN
easat-4052	276	19	for	for	ADP
easat-4052	276	20	articular	articular	ADJ
easat-4052	276	21	cartilage	cartilage	NOUN
easat-4052	276	22	repair	repair	NOUN
easat-4052	276	23	and	and	CCONJ
easat-4052	276	24	regeneration	regeneration	NOUN
easat-4052	276	25	.	.	PUNCT
easat-4052	277	1	ther	ther	PROPN
easat-4052	277	2	clin	clin	PROPN
easat-4052	277	3	risk	risk	NOUN
easat-4052	277	4	manag	manag	NOUN
easat-4052	277	5	.	.	PUNCT
easat-4052	278	1	2023;19(june):485–502	2023;19(june):485–502	PROPN
easat-4052	278	2	.	.	PUNCT
easat-4052	279	1	https://doi.org/10.2147/tcrm.s410277	https://doi.org/10.2147/tcrm.s410277	PRON
easat-4052	280	1	[	[	X
easat-4052	280	2	11	11	NUM
easat-4052	280	3	]	]	X
easat-4052	280	4	liu	liu	PROPN
easat-4052	280	5	t	t	PROPN
easat-4052	280	6	,	,	PUNCT
easat-4052	280	7	xu	xu	PROPN
easat-4052	280	8	j	j	PROPN
easat-4052	280	9	,	,	PUNCT
easat-4052	280	10	pan	pan	PROPN
easat-4052	280	11	x	x	PROPN
easat-4052	280	12	,	,	PUNCT
easat-4052	280	13	ding	de	VERB
easat-4052	280	14	z	z	PROPN
easat-4052	280	15	,	,	PUNCT
easat-4052	280	16	xie	xie	PROPN
easat-4052	280	17	h	h	PROPN
easat-4052	280	18	,	,	PUNCT
easat-4052	280	19	wang	wang	PROPN
easat-4052	280	20	x	x	PROPN
easat-4052	280	21	,	,	PUNCT
easat-4052	280	22	et	et	PROPN
easat-4052	280	23	al	al	PROPN
easat-4052	280	24	.	.	PROPN
easat-4052	280	25	advances	advance	NOUN
easat-4052	280	26	of	of	ADP
easat-4052	280	27	adipose	adipose	NOUN
easat-4052	280	28	-	-	PUNCT
easat-4052	280	29	derived	derive	VERB
easat-4052	280	30	mesenchymal	mesenchymal	NOUN
easat-4052	280	31	stem	stem	NOUN
easat-4052	280	32	cells	cell	NOUN
easat-4052	280	33	-	-	PUNCT
easat-4052	280	34	based	base	VERB
easat-4052	280	35	https://creativecommons.org/licenses/by/4.0/	https://creativecommons.org/licenses/by/4.0/	PROPN
easat-4052	280	36	9603	9603	NUM
easat-4052	280	37	edelweiss	edelweiss	PROPN
easat-4052	280	38	applied	apply	VERB
easat-4052	280	39	science	science	NOUN
easat-4052	280	40	and	and	CCONJ
easat-4052	280	41	technology	technology	NOUN
easat-4052	280	42	issn	issn	PROPN
easat-4052	280	43	:	:	PUNCT
easat-4052	280	44	2576	2576	NUM
easat-4052	280	45	-	-	SYM
easat-4052	280	46	8484	8484	NUM
easat-4052	280	47	vol	vol	NOUN
easat-4052	280	48	.	.	PROPN
easat-4052	281	1	8	8	NUM
easat-4052	281	2	,	,	PUNCT
easat-4052	281	3	no	no	INTJ
easat-4052	281	4	.	.	NOUN
easat-4052	282	1	6	6	NUM
easat-4052	282	2	:	:	SYM
easat-4052	282	3	9592	9592	NUM
easat-4052	282	4	-	-	SYM
easat-4052	282	5	9604	9604	NUM
easat-4052	282	6	,	,	PUNCT
easat-4052	282	7	2024	2024	NUM
easat-4052	282	8	doi	doi	NOUN
easat-4052	282	9	:	:	PUNCT
easat-4052	282	10	10.55214/25768484.v8i6.4052	10.55214/25768484.v8i6.4052	NUM
easat-4052	283	1	©	©	ADP
easat-4052	283	2	2024	2024	NUM
easat-4052	283	3	by	by	ADP
easat-4052	283	4	the	the	DET
easat-4052	283	5	authors	author	NOUN
easat-4052	283	6	;	;	PUNCT
easat-4052	283	7	licensee	licensee	PROPN
easat-4052	283	8	learning	learn	VERB
easat-4052	283	9	gate	gate	NOUN
easat-4052	283	10	biomaterial	biomaterial	ADJ
easat-4052	283	11	scaffolds	scaffold	NOUN
easat-4052	283	12	for	for	ADP
easat-4052	283	13	oral	oral	ADJ
easat-4052	283	14	and	and	CCONJ
easat-4052	283	15	maxillofacial	maxillofacial	ADJ
easat-4052	283	16	tissue	tissue	NOUN
easat-4052	283	17	engineering	engineering	NOUN
easat-4052	283	18	.	.	PUNCT
easat-4052	284	1	bioact	bioact	PROPN
easat-4052	284	2	mater	mater	NOUN
easat-4052	284	3	.	.	PUNCT
easat-4052	285	1	2021;6(8):2467–78	2021;6(8):2467–78	PROPN
easat-4052	285	2	.	.	PUNCT
easat-4052	286	1	https://doi.org/10.1016/j.bioactmat.2021.01.015	https://doi.org/10.1016/j.bioactmat.2021.01.015	PROPN
easat-4052	287	1	[	[	X
easat-4052	287	2	12	12	NUM
easat-4052	287	3	]	]	X
easat-4052	287	4	freitag	freitag	PROPN
easat-4052	287	5	j	j	PROPN
easat-4052	287	6	,	,	PUNCT
easat-4052	287	7	wickham	wickham	PROPN
easat-4052	287	8	j	j	PROPN
easat-4052	287	9	,	,	PUNCT
easat-4052	287	10	shah	shah	PROPN
easat-4052	287	11	k	k	PROPN
easat-4052	287	12	,	,	PUNCT
easat-4052	287	13	li	li	PROPN
easat-4052	287	14	d	d	PROPN
easat-4052	287	15	,	,	PUNCT
easat-4052	287	16	norsworthy	norsworthy	ADJ
easat-4052	287	17	c	c	NOUN
easat-4052	287	18	,	,	PUNCT
easat-4052	287	19	tenen	tenen	NOUN
easat-4052	287	20	a.	a.	NOUN
easat-4052	287	21	mesenchymal	mesenchymal	NOUN
easat-4052	287	22	stem	stem	NOUN
easat-4052	287	23	cell	cell	NOUN
easat-4052	287	24	therapy	therapy	NOUN
easat-4052	287	25	combined	combine	VERB
easat-4052	287	26	with	with	ADP
easat-4052	287	27	arthroscopic	arthroscopic	ADJ
easat-4052	287	28	abrasion	abrasion	NOUN
easat-4052	287	29	arthroplasty	arthroplasty	NOUN
easat-4052	287	30	regenerates	regenerate	VERB
easat-4052	287	31	cartilage	cartilage	NOUN
easat-4052	287	32	in	in	ADP
easat-4052	287	33	patients	patient	NOUN
easat-4052	287	34	with	with	ADP
easat-4052	287	35	severe	severe	ADJ
easat-4052	287	36	knee	knee	NOUN
easat-4052	287	37	osteoarthritis	osteoarthritis	NOUN
easat-4052	287	38	:	:	PUNCT
easat-4052	287	39	a	a	DET
easat-4052	287	40	case	case	NOUN
easat-4052	287	41	series	series	NOUN
easat-4052	287	42	.	.	PUNCT
easat-4052	288	1	regen	regen	PROPN
easat-4052	288	2	med	med	PROPN
easat-4052	288	3	.	.	PUNCT
easat-4052	289	1	2020;15(8):1957–77	2020;15(8):1957–77	ADJ
easat-4052	289	2	.	.	PUNCT
easat-4052	290	1	https://doi.org/10.2217/rme-2020-0128	https://doi.org/10.2217/rme-2020-0128	NOUN
easat-4052	291	1	[	[	X
easat-4052	291	2	13	13	NUM
easat-4052	291	3	]	]	X
easat-4052	291	4	issa	issa	PROPN
easat-4052	291	5	mr	mr	PROPN
easat-4052	291	6	,	,	PUNCT
easat-4052	291	7	naja	naja	PROPN
easat-4052	291	8	as	as	ADP
easat-4052	291	9	,	,	PUNCT
easat-4052	291	10	bouji	bouji	PROPN
easat-4052	291	11	nz	nz	PROPN
easat-4052	291	12	,	,	PUNCT
easat-4052	291	13	sagherian	sagherian	PROPN
easat-4052	291	14	bh	bh	PROPN
easat-4052	291	15	.	.	PUNCT
easat-4052	292	1	the	the	DET
easat-4052	292	2	role	role	NOUN
easat-4052	292	3	of	of	ADP
easat-4052	292	4	adipose	adipose	NOUN
easat-4052	292	5	-	-	PUNCT
easat-4052	292	6	derived	derive	VERB
easat-4052	292	7	mesenchymal	mesenchymal	NOUN
easat-4052	292	8	stem	stem	NOUN
easat-4052	292	9	cells	cell	NOUN
easat-4052	292	10	in	in	ADP
easat-4052	292	11	knee	knee	NOUN
easat-4052	292	12	osteoarthritis	osteoarthritis	NOUN
easat-4052	292	13	:	:	PUNCT
easat-4052	292	14	a	a	DET
easat-4052	292	15	meta	meta	ADJ
easat-4052	292	16	-	-	PUNCT
easat-4052	292	17	analysis	analysis	NOUN
easat-4052	292	18	of	of	ADP
easat-4052	292	19	randomized	randomized	ADJ
easat-4052	292	20	controlled	control	VERB
easat-4052	292	21	trials	trial	NOUN
easat-4052	292	22	.	.	PUNCT
easat-4052	293	1	ther	ther	PROPN
easat-4052	293	2	adv	adv	INTJ
easat-4052	293	3	musculoskelet	musculoskelet	NOUN
easat-4052	293	4	dis	dis	PROPN
easat-4052	293	5	.	.	PUNCT
easat-4052	294	1	2022;14(1):1–13	2022;14(1):1–13	X
easat-4052	294	2	.	.	PUNCT
easat-4052	295	1	https://doi.org/10.1177/1759720x	https://doi.org/10.1177/1759720x	PUNCT
easat-4052	296	1	[	[	X
easat-4052	296	2	14	14	NUM
easat-4052	296	3	]	]	X
easat-4052	296	4	liang	liang	PROPN
easat-4052	296	5	j	j	PROPN
easat-4052	296	6	,	,	PUNCT
easat-4052	296	7	liu	liu	PROPN
easat-4052	296	8	p	p	PROPN
easat-4052	296	9	,	,	PUNCT
easat-4052	296	10	yang	yang	PROPN
easat-4052	296	11	x	x	PROPN
easat-4052	296	12	,	,	PUNCT
easat-4052	296	13	liu	liu	PROPN
easat-4052	296	14	l	l	PROPN
easat-4052	296	15	,	,	PUNCT
easat-4052	296	16	zhang	zhang	PROPN
easat-4052	296	17	y	y	PROPN
easat-4052	296	18	,	,	PUNCT
easat-4052	296	19	wang	wang	PROPN
easat-4052	296	20	q	q	PROPN
easat-4052	296	21	,	,	PUNCT
easat-4052	296	22	et	et	PROPN
easat-4052	296	23	al	al	PROPN
easat-4052	296	24	.	.	PUNCT
easat-4052	296	25	biomaterial	biomaterial	NOUN
easat-4052	296	26	-	-	PUNCT
easat-4052	296	27	based	base	VERB
easat-4052	296	28	scaffolds	scaffold	NOUN
easat-4052	296	29	in	in	ADP
easat-4052	296	30	promotion	promotion	NOUN
easat-4052	296	31	of	of	ADP
easat-4052	296	32	cartilage	cartilage	NOUN
easat-4052	296	33	regeneration	regeneration	NOUN
easat-4052	296	34	:	:	PUNCT
easat-4052	296	35	recent	recent	ADJ
easat-4052	296	36	advances	advance	NOUN
easat-4052	296	37	and	and	CCONJ
easat-4052	296	38	emerging	emerge	VERB
easat-4052	296	39	applications	application	NOUN
easat-4052	296	40	.	.	PUNCT
easat-4052	297	1	j	j	PROPN
easat-4052	297	2	orthop	orthop	PROPN
easat-4052	297	3	transl	transl	PROPN
easat-4052	297	4	.	.	PUNCT
easat-4052	298	1	2023;41(june):54–62	2023;41(june):54–62	X
easat-4052	298	2	.	.	PUNCT
easat-4052	299	1	https://doi.org/10.1016/j.jot.2023.08.006	https://doi.org/10.1016/j.jot.2023.08.006	X
easat-4052	300	1	[	[	X
easat-4052	300	2	15	15	NUM
easat-4052	300	3	]	]	X
easat-4052	300	4	jelodari	jelodari	PROPN
easat-4052	300	5	s	s	X
easat-4052	300	6	,	,	PUNCT
easat-4052	300	7	ebrahimi	ebrahimi	PROPN
easat-4052	300	8	sadrabadi	sadrabadi	PROPN
easat-4052	300	9	a	a	PROPN
easat-4052	300	10	,	,	PUNCT
easat-4052	300	11	zarei	zarei	ADJ
easat-4052	300	12	f	f	X
easat-4052	300	13	,	,	PUNCT
easat-4052	300	14	jahangir	jahangir	PROPN
easat-4052	300	15	s	s	PROPN
easat-4052	300	16	,	,	PUNCT
easat-4052	300	17	azami	azami	PROPN
easat-4052	300	18	m	m	PROPN
easat-4052	300	19	,	,	PUNCT
easat-4052	300	20	sheykhhasan	sheykhhasan	PROPN
easat-4052	300	21	m	m	PROPN
easat-4052	300	22	,	,	PUNCT
easat-4052	300	23	et	et	PROPN
easat-4052	300	24	al	al	PROPN
easat-4052	300	25	.	.	PUNCT
easat-4052	301	1	new	new	ADJ
easat-4052	301	2	insights	insight	NOUN
easat-4052	301	3	into	into	ADP
easat-4052	301	4	cartilage	cartilage	NOUN
easat-4052	301	5	tissue	tissue	NOUN
easat-4052	301	6	engineering	engineering	NOUN
easat-4052	301	7	:	:	PUNCT
easat-4052	301	8	improvement	improvement	NOUN
easat-4052	301	9	of	of	ADP
easat-4052	301	10	tissue	tissue	NOUN
easat-4052	301	11	-	-	PUNCT
easat-4052	301	12	scaffold	scaffold	NOUN
easat-4052	301	13	integration	integration	NOUN
easat-4052	301	14	to	to	PART
easat-4052	301	15	enhance	enhance	VERB
easat-4052	301	16	cartilage	cartilage	NOUN
easat-4052	301	17	regeneration	regeneration	NOUN
easat-4052	301	18	.	.	PUNCT
easat-4052	301	19	biomed	biome	VERB
easat-4052	301	20	res	re	NOUN
easat-4052	301	21	int	int	NOUN
easat-4052	301	22	.	.	PUNCT
easat-4052	302	1	2022;1–3	2022;1–3	NOUN
easat-4052	302	2	.	.	PUNCT
easat-4052	303	1	https://doi.org/10.1155/2022/7638245	https://doi.org/10.1155/2022/7638245	PUNCT
easat-4052	304	1	[	[	X
easat-4052	304	2	16	16	NUM
easat-4052	304	3	]	]	X
easat-4052	304	4	yari	yari	PROPN
easat-4052	304	5	d	d	NOUN
easat-4052	304	6	,	,	PUNCT
easat-4052	304	7	ebrahimzadeh	ebrahimzadeh	PROPN
easat-4052	304	8	mh	mh	PROPN
easat-4052	304	9	,	,	PUNCT
easat-4052	304	10	movaffagh	movaffagh	PROPN
easat-4052	304	11	j	j	PROPN
easat-4052	304	12	,	,	PUNCT
easat-4052	304	13	shahroodi	shahroodi	VERB
easat-4052	304	14	a	a	PRON
easat-4052	304	15	,	,	PUNCT
easat-4052	304	16	shirzad	shirzad	PROPN
easat-4052	304	17	m	m	PROPN
easat-4052	304	18	,	,	PUNCT
easat-4052	304	19	qujeq	qujeq	VERB
easat-4052	304	20	d	d	PROPN
easat-4052	304	21	,	,	PUNCT
easat-4052	304	22	et	et	PROPN
easat-4052	304	23	al	al	PROPN
easat-4052	304	24	.	.	PUNCT
easat-4052	305	1	biochemical	biochemical	ADJ
easat-4052	305	2	aspects	aspect	NOUN
easat-4052	305	3	of	of	ADP
easat-4052	305	4	scaffolds	scaffold	NOUN
easat-4052	305	5	for	for	ADP
easat-4052	305	6	cartilage	cartilage	NOUN
easat-4052	305	7	tissue	tissue	NOUN
easat-4052	305	8	engineering	engineering	NOUN
easat-4052	305	9	;	;	PUNCT
easat-4052	305	10	from	from	ADP
easat-4052	305	11	basic	basic	ADJ
easat-4052	305	12	science	science	NOUN
easat-4052	305	13	to	to	ADP
easat-4052	305	14	regenerative	regenerative	ADJ
easat-4052	305	15	medicine	medicine	NOUN
easat-4052	305	16	.	.	PUNCT
easat-4052	306	1	arch	arch	ADJ
easat-4052	306	2	bone	bone	PROPN
easat-4052	306	3	jt	jt	PROPN
easat-4052	306	4	surg	surg	PROPN
easat-4052	306	5	.	.	PUNCT
easat-4052	307	1	2022;10(3):229	2022;10(3):229	NUM
easat-4052	307	2	–	–	PUNCT
easat-4052	307	3	44	44	NUM
easat-4052	307	4	.	.	PUNCT
easat-4052	308	1	https://doi.org/10.22038/abjs.2022.55549.2766	https://doi.org/10.22038/abjs.2022.55549.2766	NUM
easat-4052	309	1	[	[	X
easat-4052	309	2	17	17	NUM
easat-4052	309	3	]	]	PUNCT
easat-4052	309	4	perdisa	perdisa	NOUN
easat-4052	309	5	f	f	PROPN
easat-4052	309	6	,	,	PUNCT
easat-4052	309	7	gostyńska	gostyńska	NOUN
easat-4052	309	8	n	n	CCONJ
easat-4052	309	9	,	,	PUNCT
easat-4052	309	10	roffi	roffi	VERB
easat-4052	309	11	a	a	PRON
easat-4052	309	12	,	,	PUNCT
easat-4052	309	13	filardo	filardo	NOUN
easat-4052	309	14	g	g	NOUN
easat-4052	309	15	,	,	PUNCT
easat-4052	309	16	marcacci	marcacci	PROPN
easat-4052	309	17	m	m	PROPN
easat-4052	309	18	,	,	PUNCT
easat-4052	309	19	kon	kon	PROPN
easat-4052	309	20	e.	e.	PROPN
easat-4052	309	21	adipose	adipose	PROPN
easat-4052	309	22	-	-	PUNCT
easat-4052	309	23	derived	derive	VERB
easat-4052	309	24	mesenchymal	mesenchymal	NOUN
easat-4052	309	25	stem	stem	NOUN
easat-4052	309	26	cells	cell	NOUN
easat-4052	309	27	for	for	ADP
easat-4052	309	28	the	the	DET
easat-4052	309	29	treatment	treatment	NOUN
easat-4052	309	30	of	of	ADP
easat-4052	309	31	articular	articular	ADJ
easat-4052	309	32	cartilage	cartilage	NOUN
easat-4052	309	33	:	:	PUNCT
easat-4052	309	34	a	a	DET
easat-4052	309	35	systematic	systematic	ADJ
easat-4052	309	36	review	review	NOUN
easat-4052	309	37	on	on	ADP
easat-4052	309	38	preclinical	preclinical	ADJ
easat-4052	309	39	and	and	CCONJ
easat-4052	309	40	clinical	clinical	ADJ
easat-4052	309	41	evidence	evidence	NOUN
easat-4052	309	42	.	.	PUNCT
easat-4052	310	1	stem	stem	NOUN
easat-4052	310	2	cells	cell	NOUN
easat-4052	310	3	int	int	NOUN
easat-4052	310	4	.	.	PUNCT
easat-4052	311	1	2015;1	2015;1	X
easat-4052	311	2	–	–	PUNCT
easat-4052	311	3	13	13	NUM
easat-4052	311	4	.	.	PUNCT
easat-4052	312	1	https://doi.org/10.1155/2015/597652	https://doi.org/10.1155/2015/597652	PROPN
easat-4052	312	2	[	[	X
easat-4052	312	3	18	18	NUM
easat-4052	312	4	]	]	X
easat-4052	312	5	meng	meng	PROPN
easat-4052	312	6	hyh	hyh	PROPN
easat-4052	312	7	,	,	PUNCT
easat-4052	312	8	lu	lu	PROPN
easat-4052	312	9	v	v	NOUN
easat-4052	312	10	,	,	PUNCT
easat-4052	312	11	khan	khan	PROPN
easat-4052	312	12	w.	w.	PROPN
easat-4052	312	13	adipose	adipose	ADP
easat-4052	312	14	tissue	tissue	NOUN
easat-4052	312	15	-	-	PUNCT
easat-4052	312	16	derived	derive	VERB
easat-4052	312	17	mesenchymal	mesenchymal	NOUN
easat-4052	312	18	stem	stem	NOUN
easat-4052	312	19	cells	cell	NOUN
easat-4052	312	20	as	as	ADP
easat-4052	312	21	a	a	DET
easat-4052	312	22	potential	potential	ADJ
easat-4052	312	23	restorative	restorative	ADJ
easat-4052	312	24	treatment	treatment	NOUN
easat-4052	312	25	for	for	ADP
easat-4052	312	26	cartilage	cartilage	NOUN
easat-4052	312	27	defects	defect	NOUN
easat-4052	312	28	:	:	PUNCT
easat-4052	312	29	a	a	DET
easat-4052	312	30	prisma	prisma	NOUN
easat-4052	312	31	review	review	NOUN
easat-4052	312	32	and	and	CCONJ
easat-4052	312	33	meta	meta	ADJ
easat-4052	312	34	-	-	PUNCT
easat-4052	312	35	analysis	analysis	NOUN
easat-4052	312	36	.	.	PUNCT
easat-4052	313	1	pharmaceuticals	pharmaceutical	NOUN
easat-4052	313	2	.	.	PUNCT
easat-4052	314	1	2021;14(12):1–25	2021;14(12):1–25	NUM
easat-4052	314	2	.	.	PUNCT
easat-4052	315	1	https://doi.org/10.3390/ph14121280	https://doi.org/10.3390/ph14121280	PRON
easat-4052	315	2	[	[	X
easat-4052	315	3	19	19	NUM
easat-4052	315	4	]	]	PUNCT
easat-4052	315	5	song	song	NOUN
easat-4052	315	6	k	k	PROPN
easat-4052	315	7	,	,	PUNCT
easat-4052	315	8	li	li	PROPN
easat-4052	315	9	l	l	PROPN
easat-4052	315	10	,	,	PUNCT
easat-4052	315	11	yan	yan	PROPN
easat-4052	315	12	x	x	X
easat-4052	315	13	,	,	PUNCT
easat-4052	315	14	zhang	zhang	PROPN
easat-4052	315	15	y	y	PROPN
easat-4052	315	16	,	,	PUNCT
easat-4052	315	17	li	li	PROPN
easat-4052	315	18	r	r	PROPN
easat-4052	315	19	,	,	PUNCT
easat-4052	315	20	wang	wang	PROPN
easat-4052	315	21	y	y	PROPN
easat-4052	315	22	,	,	PUNCT
easat-4052	315	23	et	et	PROPN
easat-4052	315	24	al	al	PROPN
easat-4052	315	25	.	.	PROPN
easat-4052	315	26	fabrication	fabrication	NOUN
easat-4052	315	27	and	and	CCONJ
easat-4052	315	28	development	development	NOUN
easat-4052	315	29	of	of	ADP
easat-4052	315	30	artificial	artificial	ADJ
easat-4052	315	31	osteochondral	osteochondral	ADJ
easat-4052	315	32	constructs	construct	NOUN
easat-4052	315	33	based	base	VERB
easat-4052	315	34	on	on	ADP
easat-4052	315	35	cancellous	cancellous	ADJ
easat-4052	315	36	bone	bone	NOUN
easat-4052	315	37	/	/	SYM
easat-4052	315	38	hydrogel	hydrogel	NOUN
easat-4052	315	39	hybrid	hybrid	NOUN
easat-4052	315	40	scaffold	scaffold	NOUN
easat-4052	315	41	.	.	PUNCT
easat-4052	316	1	j	j	PROPN
easat-4052	316	2	mater	mater	NOUN
easat-4052	316	3	sci	sci	PROPN
easat-4052	316	4	mater	mater	NOUN
easat-4052	316	5	med	med	PROPN
easat-4052	316	6	.	.	PUNCT
easat-4052	317	1	2016;27(6):1–12	2016;27(6):1–12	NUM
easat-4052	317	2	.	.	PUNCT
easat-4052	318	1	https://doi.org/10.1007/s10856-016-5722-5	https://doi.org/10.1007/s10856-016-5722-5	NUM
easat-4052	319	1	[	[	X
easat-4052	319	2	20	20	NUM
easat-4052	319	3	]	]	X
easat-4052	319	4	zhang	zhang	PROPN
easat-4052	320	1	k	k	PROPN
easat-4052	320	2	,	,	PUNCT
easat-4052	320	3	he	he	PRON
easat-4052	320	4	s	s	PROPN
easat-4052	320	5	,	,	PUNCT
easat-4052	320	6	yan	yan	PROPN
easat-4052	320	7	s	s	PROPN
easat-4052	320	8	,	,	PUNCT
easat-4052	320	9	li	li	PROPN
easat-4052	320	10	g	g	PROPN
easat-4052	320	11	,	,	PUNCT
easat-4052	320	12	zhang	zhang	PROPN
easat-4052	320	13	d	d	PROPN
easat-4052	320	14	,	,	PUNCT
easat-4052	320	15	cui	cui	PROPN
easat-4052	320	16	l	l	PROPN
easat-4052	320	17	,	,	PUNCT
easat-4052	320	18	et	et	PROPN
easat-4052	320	19	al	al	PROPN
easat-4052	320	20	.	.	PROPN
easat-4052	321	1	regeneration	regeneration	NOUN
easat-4052	321	2	of	of	ADP
easat-4052	321	3	hyaline	hyaline	NOUN
easat-4052	321	4	-	-	PUNCT
easat-4052	321	5	like	like	ADJ
easat-4052	321	6	cartilage	cartilage	NOUN
easat-4052	321	7	and	and	CCONJ
easat-4052	321	8	subchondral	subchondral	ADJ
easat-4052	321	9	bone	bone	NOUN
easat-4052	321	10	simultaneously	simultaneously	ADV
easat-4052	321	11	by	by	ADP
easat-4052	321	12	poly(l	poly(l	ADJ
easat-4052	321	13	-	-	PUNCT
easat-4052	321	14	glutamic	glutamic	ADJ
easat-4052	321	15	acid	acid	NOUN
easat-4052	321	16	)	)	PUNCT
easat-4052	321	17	based	base	VERB
easat-4052	321	18	osteochondral	osteochondral	ADJ
easat-4052	321	19	scaffolds	scaffold	NOUN
easat-4052	321	20	with	with	ADP
easat-4052	321	21	induced	induce	VERB
easat-4052	321	22	autologous	autologous	ADJ
easat-4052	321	23	adipose	adipose	ADJ
easat-4052	321	24	derived	derive	VERB
easat-4052	321	25	stem	stem	NOUN
easat-4052	321	26	cells	cell	NOUN
easat-4052	321	27	.	.	PUNCT
easat-4052	322	1	vol	vol	NOUN
easat-4052	322	2	.	.	PROPN
easat-4052	322	3	4	4	NUM
easat-4052	322	4	,	,	PUNCT
easat-4052	322	5	journal	journal	NOUN
easat-4052	322	6	of	of	ADP
easat-4052	322	7	materials	material	NOUN
easat-4052	322	8	chemistry	chemistry	NOUN
easat-4052	322	9	b.	b.	PROPN
easat-4052	322	10	2016	2016	NUM
easat-4052	322	11	.	.	PUNCT
easat-4052	323	1	2628–2645	2628–2645	NUM
easat-4052	323	2	p.	p.	NOUN
easat-4052	323	3	https://doi.org/10.1039/c5tb02113h	https://doi.org/10.1039/c5tb02113h	PROPN
easat-4052	324	1	[	[	X
easat-4052	324	2	21	21	NUM
easat-4052	324	3	]	]	X
easat-4052	324	4	nordberg	nordberg	PROPN
easat-4052	324	5	rc	rc	PROPN
easat-4052	324	6	,	,	PUNCT
easat-4052	324	7	huebner	huebner	PROPN
easat-4052	324	8	p	p	PROPN
easat-4052	324	9	,	,	PUNCT
easat-4052	324	10	schuchard	schuchard	PROPN
easat-4052	324	11	kg	kg	PROPN
easat-4052	324	12	,	,	PUNCT
easat-4052	324	13	mellor	mellor	PROPN
easat-4052	324	14	lf	lf	PROPN
easat-4052	324	15	,	,	PUNCT
easat-4052	324	16	shirwaiker	shirwaiker	PROPN
easat-4052	324	17	ra	ra	PROPN
easat-4052	324	18	,	,	PUNCT
easat-4052	324	19	loboa	loboa	PROPN
easat-4052	324	20	eg	eg	NOUN
easat-4052	324	21	,	,	PUNCT
easat-4052	324	22	et	et	PROPN
easat-4052	324	23	al	al	PROPN
easat-4052	324	24	.	.	PUNCT
easat-4052	325	1	the	the	DET
easat-4052	325	2	evaluation	evaluation	NOUN
easat-4052	325	3	of	of	ADP
easat-4052	325	4	a	a	DET
easat-4052	325	5	multiphasic	multiphasic	NOUN
easat-4052	325	6	3d	3d	NOUN
easat-4052	325	7	-	-	PUNCT
easat-4052	325	8	bioplotted	bioplotte	VERB
easat-4052	325	9	scaffold	scaffold	NOUN
easat-4052	325	10	seeded	seed	VERB
easat-4052	325	11	with	with	ADP
easat-4052	325	12	adipose	adipose	ADJ
easat-4052	325	13	derived	derive	VERB
easat-4052	325	14	stem	stem	NOUN
easat-4052	325	15	cells	cell	NOUN
easat-4052	325	16	to	to	PART
easat-4052	325	17	repair	repair	VERB
easat-4052	325	18	osteochondral	osteochondral	ADJ
easat-4052	325	19	defects	defect	NOUN
easat-4052	325	20	in	in	ADP
easat-4052	325	21	a	a	DET
easat-4052	325	22	porcine	porcine	NOUN
easat-4052	325	23	model	model	NOUN
easat-4052	325	24	.	.	PUNCT
easat-4052	326	1	j	j	PROPN
easat-4052	326	2	biomed	biome	VERB
easat-4052	326	3	mater	mater	NOUN
easat-4052	326	4	res	re	NOUN
easat-4052	326	5	part	part	NOUN
easat-4052	326	6	b	b	PROPN
easat-4052	326	7	appl	appl	PROPN
easat-4052	326	8	biomater	biomater	NOUN
easat-4052	326	9	.	.	PUNCT
easat-4052	327	1	2021;109(12):2246–58	2021;109(12):2246–58	NUM
easat-4052	327	2	.	.	PUNCT
easat-4052	328	1	[	[	X
easat-4052	328	2	22	22	NUM
easat-4052	328	3	]	]	X
easat-4052	328	4	zhong	zhong	PROPN
easat-4052	328	5	l	l	PROPN
easat-4052	328	6	,	,	PUNCT
easat-4052	328	7	yao	yao	PROPN
easat-4052	328	8	l	l	NOUN
easat-4052	328	9	,	,	PUNCT
easat-4052	328	10	seale	seale	PROPN
easat-4052	328	11	p	p	X
easat-4052	328	12	,	,	PUNCT
easat-4052	328	13	qin	qin	PROPN
easat-4052	328	14	l.	l.	PROPN
easat-4052	328	15	marrow	marrow	PROPN
easat-4052	328	16	adipogenic	adipogenic	ADJ
easat-4052	328	17	lineage	lineage	NOUN
easat-4052	328	18	precursor	precursor	NOUN
easat-4052	328	19	:	:	PUNCT
easat-4052	328	20	a	a	DET
easat-4052	328	21	new	new	ADJ
easat-4052	328	22	cellular	cellular	ADJ
easat-4052	328	23	component	component	NOUN
easat-4052	328	24	of	of	ADP
easat-4052	328	25	marrow	marrow	NOUN
easat-4052	328	26	adipose	adipose	ADJ
easat-4052	328	27	tissue	tissue	NOUN
easat-4052	328	28	.	.	PUNCT
easat-4052	329	1	best	good	ADJ
easat-4052	329	2	pract	pract	PROPN
easat-4052	329	3	res	re	NOUN
easat-4052	329	4	clin	clin	PROPN
easat-4052	329	5	endocrinol	endocrinol	NOUN
easat-4052	329	6	metab	metab	NOUN
easat-4052	329	7	.	.	PUNCT
easat-4052	330	1	2021;35(4):1–23	2021;35(4):1–23	X
easat-4052	330	2	.	.	PUNCT
easat-4052	331	1	[	[	X
easat-4052	331	2	23	23	NUM
easat-4052	331	3	]	]	PUNCT
easat-4052	331	4	ow	ow	INTJ
easat-4052	331	5	zgw	zgw	PROPN
easat-4052	331	6	,	,	PUNCT
easat-4052	331	7	lim	lim	PROPN
easat-4052	331	8	kkl	kkl	PROPN
easat-4052	331	9	,	,	PUNCT
easat-4052	331	10	sin	sin	PROPN
easat-4052	331	11	sq	sq	PROPN
easat-4052	331	12	,	,	PUNCT
easat-4052	331	13	cheang	cheang	PROPN
easat-4052	331	14	hlx	hlx	PROPN
easat-4052	331	15	,	,	PUNCT
easat-4052	331	16	wang	wang	PROPN
easat-4052	331	17	d	d	PROPN
easat-4052	331	18	,	,	PUNCT
easat-4052	331	19	lie	lie	NOUN
easat-4052	331	20	dtt	dtt	NOUN
easat-4052	331	21	,	,	PUNCT
easat-4052	331	22	et	et	PROPN
easat-4052	331	23	al	al	PROPN
easat-4052	331	24	.	.	PROPN
easat-4052	332	1	similar	similar	ADJ
easat-4052	332	2	short	short	ADJ
easat-4052	332	3	-	-	PUNCT
easat-4052	332	4	term	term	NOUN
easat-4052	332	5	results	result	NOUN
easat-4052	332	6	between	between	ADP
easat-4052	332	7	scaffold	scaffold	NOUN
easat-4052	332	8	implanted	implant	VERB
easat-4052	332	9	mesenchymal	mesenchymal	NOUN
easat-4052	332	10	stem	stem	NOUN
easat-4052	332	11	cells	cell	NOUN
easat-4052	332	12	vs	vs	ADP
easat-4052	332	13	acellular	acellular	ADJ
easat-4052	332	14	scaffolds	scaffold	NOUN
easat-4052	332	15	with	with	ADP
easat-4052	332	16	concentrated	concentrate	VERB
easat-4052	332	17	bone	bone	NOUN
easat-4052	332	18	marrow	marrow	NOUN
easat-4052	332	19	aspirate	aspirate	NOUN
easat-4052	332	20	augmentation	augmentation	NOUN
easat-4052	332	21	for	for	ADP
easat-4052	332	22	the	the	DET
easat-4052	332	23	repair	repair	NOUN
easat-4052	332	24	of	of	ADP
easat-4052	332	25	chondral	chondral	ADJ
easat-4052	332	26	defects	defect	NOUN
easat-4052	332	27	of	of	ADP
easat-4052	332	28	the	the	DET
easat-4052	332	29	knee	knee	NOUN
easat-4052	332	30	:	:	PUNCT
easat-4052	332	31	evidence	evidence	NOUN
easat-4052	332	32	from	from	ADP
easat-4052	332	33	a	a	DET
easat-4052	332	34	meta	meta	ADJ
easat-4052	332	35	-	-	PUNCT
easat-4052	332	36	analysis	analysis	NOUN
easat-4052	332	37	.	.	PUNCT
easat-4052	333	1	j	j	PROPN
easat-4052	333	2	cartil	cartil	PROPN
easat-4052	333	3	jt	jt	PROPN
easat-4052	333	4	preserv	preserv	NOUN
easat-4052	333	5	.	.	PUNCT
easat-4052	334	1	2023;3(4):100128	2023;3(4):100128	X
easat-4052	334	2	.	.	PUNCT
easat-4052	335	1	https://doi.org/10.1016/j.jcjp.2023.100128	https://doi.org/10.1016/j.jcjp.2023.100128	PROPN
easat-4052	335	2	[	[	X
easat-4052	335	3	24	24	NUM
easat-4052	335	4	]	]	X
easat-4052	335	5	kangari	kangari	PROPN
easat-4052	335	6	p	p	NOUN
easat-4052	335	7	,	,	PUNCT
easat-4052	335	8	talaei	talaei	ADJ
easat-4052	335	9	-	-	PUNCT
easat-4052	335	10	khozani	khozani	ADJ
easat-4052	335	11	t	t	PROPN
easat-4052	335	12	,	,	PUNCT
easat-4052	335	13	razeghian	razeghian	ADJ
easat-4052	335	14	-	-	PUNCT
easat-4052	335	15	jahromi	jahromi	NOUN
easat-4052	335	16	i	i	PRON
easat-4052	335	17	,	,	PUNCT
easat-4052	335	18	razmkhah	razmkhah	PROPN
easat-4052	335	19	m.	m.	NOUN
easat-4052	335	20	mesenchymal	mesenchymal	NOUN
easat-4052	335	21	stem	stem	NOUN
easat-4052	335	22	cells	cell	NOUN
easat-4052	335	23	:	:	PUNCT
easat-4052	335	24	amazing	amazing	ADJ
easat-4052	335	25	remedies	remedy	NOUN
easat-4052	335	26	for	for	ADP
easat-4052	335	27	bone	bone	NOUN
easat-4052	335	28	and	and	CCONJ
easat-4052	335	29	cartilage	cartilage	NOUN
easat-4052	335	30	defects	defect	NOUN
easat-4052	335	31	.	.	PUNCT
easat-4052	336	1	stem	stem	NOUN
easat-4052	336	2	cell	cell	NOUN
easat-4052	336	3	res	re	NOUN
easat-4052	336	4	ther	ther	ADV
easat-4052	336	5	.	.	PUNCT
easat-4052	337	1	2020;11(1):1–21	2020;11(1):1–21	X
easat-4052	337	2	.	.	PUNCT
easat-4052	338	1	https://doi.org/10.1186/s13287-020-02001-1	https://doi.org/10.1186/s13287-020-02001-1	NUM
easat-4052	339	1	[	[	X
easat-4052	339	2	25	25	NUM
easat-4052	339	3	]	]	X
easat-4052	340	1	zhang	zhang	PROPN
easat-4052	340	2	z	z	PROPN
easat-4052	340	3	,	,	PUNCT
easat-4052	340	4	yang	yang	PROPN
easat-4052	340	5	x	x	PROPN
easat-4052	340	6	,	,	PUNCT
easat-4052	340	7	cao	cao	PROPN
easat-4052	340	8	x	x	PROPN
easat-4052	340	9	,	,	PUNCT
easat-4052	340	10	qin	qin	PROPN
easat-4052	340	11	a	a	X
easat-4052	340	12	,	,	PUNCT
easat-4052	340	13	zhao	zhao	PROPN
easat-4052	340	14	j.	j.	PROPN
easat-4052	340	15	current	current	ADJ
easat-4052	340	16	applications	application	NOUN
easat-4052	340	17	of	of	ADP
easat-4052	340	18	adipose	adipose	NOUN
easat-4052	340	19	-	-	PUNCT
easat-4052	340	20	derived	derive	VERB
easat-4052	340	21	mesenchymal	mesenchymal	NOUN
easat-4052	340	22	stem	stem	NOUN
easat-4052	340	23	cells	cell	NOUN
easat-4052	340	24	in	in	ADP
easat-4052	340	25	bone	bone	NOUN
easat-4052	340	26	repair	repair	NOUN
easat-4052	340	27	and	and	CCONJ
easat-4052	340	28	regeneration	regeneration	NOUN
easat-4052	340	29	:	:	PUNCT
easat-4052	340	30	a	a	DET
easat-4052	340	31	review	review	NOUN
easat-4052	340	32	of	of	ADP
easat-4052	340	33	cell	cell	NOUN
easat-4052	340	34	experiments	experiment	NOUN
easat-4052	340	35	,	,	PUNCT
easat-4052	340	36	animal	animal	NOUN
easat-4052	340	37	models	model	NOUN
easat-4052	340	38	,	,	PUNCT
easat-4052	340	39	and	and	CCONJ
easat-4052	340	40	clinical	clinical	ADJ
easat-4052	340	41	trials	trial	NOUN
easat-4052	340	42	.	.	PUNCT
easat-4052	341	1	front	front	ADJ
easat-4052	341	2	bioeng	bioeng	PROPN
easat-4052	341	3	biotechnol	biotechnol	NOUN
easat-4052	341	4	.	.	PUNCT
easat-4052	342	1	2022;10(september):1–18	2022;10(september):1–18	NUM
easat-4052	342	2	.	.	PUNCT
easat-4052	342	3	https://doi.org/10.3389/fbioe.2022.942128	https://doi.org/10.3389/fbioe.2022.942128	PROPN
easat-4052	343	1	[	[	X
easat-4052	343	2	26	26	NUM
easat-4052	343	3	]	]	X
easat-4052	343	4	lau	lau	PROPN
easat-4052	343	5	cs	cs	PROPN
easat-4052	343	6	,	,	PUNCT
easat-4052	343	7	park	park	NOUN
easat-4052	343	8	sy	sy	PROPN
easat-4052	343	9	,	,	PUNCT
easat-4052	343	10	ethiraj	ethiraj	PROPN
easat-4052	343	11	lp	lp	PROPN
easat-4052	343	12	,	,	PUNCT
easat-4052	343	13	singh	singh	PROPN
easat-4052	343	14	p	p	NOUN
easat-4052	343	15	,	,	PUNCT
easat-4052	343	16	raj	raj	PROPN
easat-4052	343	17	g	g	PROPN
easat-4052	343	18	,	,	PUNCT
easat-4052	343	19	quek	quek	PROPN
easat-4052	343	20	j	j	PROPN
easat-4052	343	21	,	,	PUNCT
easat-4052	343	22	et	et	PROPN
easat-4052	343	23	al	al	PROPN
easat-4052	343	24	.	.	PROPN
easat-4052	343	25	role	role	NOUN
easat-4052	343	26	of	of	ADP
easat-4052	343	27	adipose	adipose	NOUN
easat-4052	343	28	-	-	PUNCT
easat-4052	343	29	derived	derive	VERB
easat-4052	343	30	mesenchymal	mesenchymal	NOUN
easat-4052	343	31	stem	stem	NOUN
easat-4052	343	32	cells	cell	NOUN
easat-4052	343	33	in	in	ADP
easat-4052	343	34	bone	bone	NOUN
easat-4052	343	35	regeneration	regeneration	NOUN
easat-4052	343	36	.	.	PUNCT
easat-4052	344	1	int	int	PROPN
easat-4052	344	2	j	j	PROPN
easat-4052	344	3	mol	mol	ADP
easat-4052	344	4	sci	sci	PROPN
easat-4052	344	5	.	.	PUNCT
easat-4052	345	1	2024;25(12):1–44	2024;25(12):1–44	NUM
easat-4052	345	2	.	.	PUNCT
easat-4052	346	1	https://doi.org/10.3390/ijms25126805	https://doi.org/10.3390/ijms25126805	PROPN
easat-4052	347	1	[	[	X
easat-4052	347	2	27	27	NUM
easat-4052	347	3	]	]	X
easat-4052	347	4	ma	ma	PROPN
easat-4052	347	5	h	h	PROPN
easat-4052	347	6	,	,	PUNCT
easat-4052	347	7	lam	lam	PROPN
easat-4052	347	8	pk	pk	PROPN
easat-4052	347	9	,	,	PUNCT
easat-4052	347	10	siu	siu	NOUN
easat-4052	347	11	ws	ws	NOUN
easat-4052	347	12	,	,	PUNCT
easat-4052	347	13	tong	tong	PROPN
easat-4052	347	14	csw	csw	PROPN
easat-4052	347	15	,	,	PUNCT
easat-4052	347	16	lo	lo	PROPN
easat-4052	347	17	kky	kky	PROPN
easat-4052	347	18	,	,	PUNCT
easat-4052	347	19	koon	koon	PROPN
easat-4052	347	20	cm	cm	PROPN
easat-4052	347	21	,	,	PUNCT
easat-4052	347	22	et	et	PROPN
easat-4052	347	23	al	al	PROPN
easat-4052	347	24	.	.	PROPN
easat-4052	348	1	adipose	adipose	ADP
easat-4052	348	2	tissue	tissue	NOUN
easat-4052	348	3	-	-	PUNCT
easat-4052	348	4	derived	derive	VERB
easat-4052	348	5	mesenchymal	mesenchymal	NOUN
easat-4052	348	6	stem	stem	NOUN
easat-4052	348	7	cells	cell	NOUN
easat-4052	348	8	(	(	PUNCT
easat-4052	348	9	admsc	admsc	NOUN
easat-4052	348	10	)	)	PUNCT
easat-4052	348	11	and	and	CCONJ
easat-4052	348	12	admsc	admsc	NOUN
easat-4052	348	13	-	-	PUNCT
easat-4052	348	14	derived	derive	VERB
easat-4052	348	15	secretome	secretome	NOUN
easat-4052	348	16	expedited	expedite	VERB
easat-4052	348	17	wound	wound	NOUN
easat-4052	348	18	healing	healing	NOUN
easat-4052	348	19	in	in	ADP
easat-4052	348	20	a	a	DET
easat-4052	348	21	rodent	rodent	ADJ
easat-4052	348	22	model	model	NOUN
easat-4052	348	23	–	–	PUNCT
easat-4052	348	24	a	a	DET
easat-4052	348	25	preliminary	preliminary	ADJ
easat-4052	348	26	study	study	NOUN
easat-4052	348	27	.	.	PUNCT
easat-4052	349	1	clin	clin	PROPN
easat-4052	349	2	cosmet	cosmet	PROPN
easat-4052	349	3	investig	investig	NOUN
easat-4052	349	4	dermatol	dermatol	NOUN
easat-4052	349	5	.	.	PUNCT
easat-4052	350	1	2021;14(december	2021;14(december	PROPN
easat-4052	350	2	2020):753–64	2020):753–64	NUM
easat-4052	350	3	.	.	PUNCT
easat-4052	351	1	https://doi.org/10.2147/ccid.s298105	https://doi.org/10.2147/ccid.s298105	PROPN
easat-4052	352	1	[	[	X
easat-4052	352	2	28	28	NUM
easat-4052	352	3	]	]	X
easat-4052	352	4	henckes	hencke	VERB
easat-4052	352	5	nac	nac	PROPN
easat-4052	352	6	,	,	PUNCT
easat-4052	352	7	faleiro	faleiro	PROPN
easat-4052	352	8	d	d	PROPN
easat-4052	352	9	,	,	PUNCT
easat-4052	352	10	chuang	chuang	PROPN
easat-4052	352	11	lc	lc	PROPN
easat-4052	352	12	,	,	PUNCT
easat-4052	352	13	cirne	cirne	ADJ
easat-4052	352	14	-	-	PUNCT
easat-4052	352	15	lima	lima	NOUN
easat-4052	352	16	eo	eo	PROPN
easat-4052	352	17	.	.	PROPN
easat-4052	353	1	scaffold	scaffold	NOUN
easat-4052	353	2	strategies	strategy	NOUN
easat-4052	353	3	combined	combine	VERB
easat-4052	353	4	with	with	ADP
easat-4052	353	5	mesenchymal	mesenchymal	ADJ
easat-4052	353	6	stem	stem	NOUN
easat-4052	353	7	cells	cell	NOUN
easat-4052	353	8	in	in	ADP
easat-4052	353	9	vaginal	vaginal	ADJ
easat-4052	353	10	construction	construction	NOUN
easat-4052	353	11	:	:	PUNCT
easat-4052	353	12	a	a	DET
easat-4052	353	13	review	review	NOUN
easat-4052	353	14	.	.	PUNCT
easat-4052	354	1	cell	cell	NOUN
easat-4052	354	2	regen	regen	PROPN
easat-4052	354	3	.	.	PUNCT
easat-4052	355	1	2021;10(1):1–11	2021;10(1):1–11	NUM
easat-4052	355	2	.	.	PUNCT
easat-4052	355	3	https://doi.org/10.1186/s13619-021-00088-2	https://doi.org/10.1186/s13619-021-00088-2	NUM
easat-4052	356	1	[	[	X
easat-4052	356	2	29	29	NUM
easat-4052	356	3	]	]	PUNCT
easat-4052	356	4	bunnell	bunnell	PROPN
easat-4052	356	5	ba	ba	PROPN
easat-4052	356	6	.	.	PUNCT
easat-4052	357	1	adipose	adipose	ADP
easat-4052	357	2	tissue	tissue	NOUN
easat-4052	357	3	-	-	PUNCT
easat-4052	357	4	derived	derive	VERB
easat-4052	357	5	mesenchymal	mesenchymal	NOUN
easat-4052	357	6	stem	stem	NOUN
easat-4052	357	7	cells	cell	NOUN
easat-4052	357	8	.	.	PUNCT
easat-4052	358	1	cells	cell	NOUN
easat-4052	358	2	.	.	PUNCT
easat-4052	359	1	2021;10(1):1–7	2021;10(1):1–7	NUM
easat-4052	359	2	.	.	PUNCT
easat-4052	360	1	https://doi.org/10.3390/cells10123433	https://doi.org/10.3390/cells10123433	PROPN
easat-4052	361	1	[	[	X
easat-4052	361	2	30	30	NUM
easat-4052	361	3	]	]	X
easat-4052	361	4	francis	francis	PROPN
easat-4052	361	5	sl	sl	PROPN
easat-4052	361	6	,	,	PUNCT
easat-4052	361	7	duchi	duchi	PROPN
easat-4052	361	8	s	s	PART
easat-4052	361	9	,	,	PUNCT
easat-4052	361	10	onofrillo	onofrillo	PROPN
easat-4052	361	11	c	c	NOUN
easat-4052	361	12	,	,	PUNCT
easat-4052	361	13	di	di	X
easat-4052	361	14	bella	bella	PROPN
easat-4052	361	15	c	c	PROPN
easat-4052	361	16	,	,	PUNCT
easat-4052	361	17	choong	choong	PROPN
easat-4052	361	18	pfm	pfm	PROPN
easat-4052	361	19	.	.	PUNCT
easat-4052	362	1	adipose	adipose	NOUN
easat-4052	362	2	-	-	PUNCT
easat-4052	362	3	derived	derive	VERB
easat-4052	362	4	mesenchymal	mesenchymal	NOUN
easat-4052	362	5	stem	stem	NOUN
easat-4052	362	6	cells	cell	NOUN
easat-4052	362	7	in	in	ADP
easat-4052	362	8	the	the	DET
easat-4052	362	9	use	use	NOUN
easat-4052	362	10	of	of	ADP
easat-4052	362	11	cartilage	cartilage	NOUN
easat-4052	362	12	tissue	tissue	NOUN
easat-4052	362	13	engineering	engineering	NOUN
easat-4052	362	14	:	:	PUNCT
easat-4052	362	15	the	the	DET
easat-4052	362	16	need	need	NOUN
easat-4052	362	17	for	for	ADP
easat-4052	362	18	a	a	DET
easat-4052	362	19	rapid	rapid	ADJ
easat-4052	362	20	isolation	isolation	NOUN
easat-4052	362	21	procedure	procedure	NOUN
easat-4052	362	22	.	.	PUNCT
easat-4052	363	1	stem	stem	NOUN
easat-4052	363	2	cells	cell	NOUN
easat-4052	363	3	int	int	NOUN
easat-4052	363	4	.	.	PUNCT
easat-4052	364	1	2018;13–6	2018;13–6	NOUN
easat-4052	364	2	.	.	PUNCT
easat-4052	365	1	https://doi.org/10.1155/2018/8947548	https://doi.org/10.1155/2018/8947548	PROPN
easat-4052	366	1	[	[	X
easat-4052	366	2	31	31	NUM
easat-4052	366	3	]	]	X
easat-4052	366	4	zha	zha	PROPN
easat-4052	366	5	k	k	PROPN
easat-4052	366	6	,	,	PUNCT
easat-4052	366	7	li	li	PROPN
easat-4052	366	8	x	x	PROPN
easat-4052	366	9	,	,	PUNCT
easat-4052	366	10	yang	yang	PROPN
easat-4052	366	11	z	z	PROPN
easat-4052	366	12	,	,	PUNCT
easat-4052	366	13	tian	tian	PROPN
easat-4052	366	14	g	g	PROPN
easat-4052	366	15	,	,	PUNCT
easat-4052	366	16	sun	sun	PROPN
easat-4052	366	17	z	z	PROPN
easat-4052	366	18	,	,	PUNCT
easat-4052	366	19	sui	sui	PROPN
easat-4052	366	20	x	x	SYM
easat-4052	366	21	,	,	PUNCT
easat-4052	366	22	et	et	PROPN
easat-4052	366	23	al	al	PROPN
easat-4052	366	24	.	.	PUNCT
easat-4052	366	25	heterogeneity	heterogeneity	NOUN
easat-4052	366	26	of	of	ADP
easat-4052	366	27	mesenchymal	mesenchymal	ADJ
easat-4052	366	28	stem	stem	NOUN
easat-4052	366	29	cells	cell	NOUN
easat-4052	366	30	in	in	ADP
easat-4052	366	31	cartilage	cartilage	NOUN
easat-4052	366	32	regeneration	regeneration	NOUN
easat-4052	366	33	:	:	PUNCT
easat-4052	366	34	from	from	ADP
easat-4052	366	35	characterization	characterization	NOUN
easat-4052	366	36	to	to	ADP
easat-4052	366	37	application	application	NOUN
easat-4052	366	38	.	.	PUNCT
easat-4052	367	1	regen	regen	PROPN
easat-4052	367	2	med	med	PROPN
easat-4052	367	3	.	.	PUNCT
easat-4052	368	1	2021;6(1):1–15	2021;6(1):1–15	NUM
easat-4052	368	2	.	.	X
easat-4052	369	1	https://doi.org/10.1038/s41536-021-00122-6	https://doi.org/10.1038/s41536-021-00122-6	PROPN
easat-4052	370	1	[	[	X
easat-4052	370	2	32	32	NUM
easat-4052	370	3	]	]	PUNCT
easat-4052	370	4	gherghel	gherghel	PROPN
easat-4052	370	5	r	r	PROPN
easat-4052	370	6	,	,	PUNCT
easat-4052	370	7	macovei	macovei	NOUN
easat-4052	370	8	la	la	PROPN
easat-4052	370	9	,	,	PUNCT
easat-4052	370	10	burlui	burlui	PROPN
easat-4052	370	11	ma	ma	PROPN
easat-4052	370	12	,	,	PUNCT
easat-4052	370	13	cardoneanu	cardoneanu	VERB
easat-4052	370	14	a	a	DET
easat-4052	370	15	,	,	PUNCT
easat-4052	370	16	rezus	rezus	PROPN
easat-4052	370	17	ii	ii	PROPN
easat-4052	370	18	,	,	PUNCT
easat-4052	370	19	mihai	mihai	PROPN
easat-4052	370	20	ir	ir	PROPN
easat-4052	370	21	,	,	PUNCT
easat-4052	370	22	et	et	PROPN
easat-4052	370	23	al	al	PROPN
easat-4052	370	24	.	.	PUNCT
easat-4052	371	1	osteoarthritis	osteoarthritis	PROPN
easat-4052	371	2	—	—	PUNCT
easat-4052	371	3	the	the	DET
easat-4052	371	4	role	role	NOUN
easat-4052	371	5	of	of	ADP
easat-4052	371	6	mesenchymal	mesenchymal	ADJ
easat-4052	371	7	stem	stem	NOUN
easat-4052	371	8	cells	cell	NOUN
easat-4052	371	9	in	in	ADP
easat-4052	371	10	cartilage	cartilage	NOUN
easat-4052	371	11	regeneration	regeneration	NOUN
easat-4052	371	12	.	.	PUNCT
easat-4052	372	1	appl	appl	PROPN
easat-4052	372	2	sci	sci	PROPN
easat-4052	372	3	.	.	PUNCT
easat-4052	373	1	2023;13(19):1–33	2023;13(19):1–33	NUM
easat-4052	373	2	.	.	PUNCT
easat-4052	374	1	[	[	X
easat-4052	374	2	33	33	NUM
easat-4052	374	3	]	]	X
easat-4052	374	4	lee	lee	PROPN
easat-4052	374	5	h	h	PROPN
easat-4052	374	6	,	,	PUNCT
easat-4052	374	7	lim	lim	PROPN
easat-4052	374	8	y	y	PROPN
easat-4052	374	9	,	,	PUNCT
easat-4052	374	10	lee	lee	PROPN
easat-4052	374	11	sh	sh	PROPN
easat-4052	374	12	.	.	PROPN
easat-4052	374	13	rapid	rapid	ADJ
easat-4052	374	14	-	-	PUNCT
easat-4052	374	15	acting	act	VERB
easat-4052	374	16	pain	pain	NOUN
easat-4052	374	17	relief	relief	NOUN
easat-4052	374	18	in	in	ADP
easat-4052	374	19	knee	knee	NOUN
easat-4052	374	20	osteoarthritis	osteoarthritis	NOUN
easat-4052	374	21	:	:	PUNCT
easat-4052	374	22	autologous	autologous	ADJ
easat-4052	374	23	-	-	PUNCT
easat-4052	374	24	cultured	cultured	ADJ
easat-4052	374	25	adipose	adipose	NOUN
easat-4052	374	26	-	-	PUNCT
easat-4052	374	27	derived	derive	VERB
easat-4052	374	28	mesenchymal	mesenchymal	NOUN
easat-4052	374	29	stem	stem	NOUN
easat-4052	374	30	cells	cell	NOUN
easat-4052	374	31	outperform	outperform	VERB
easat-4052	374	32	stromal	stromal	ADJ
easat-4052	374	33	vascular	vascular	ADJ
easat-4052	374	34	fraction	fraction	NOUN
easat-4052	374	35	:	:	PUNCT
easat-4052	374	36	a	a	DET
easat-4052	374	37	systematic	systematic	ADJ
easat-4052	374	38	review	review	NOUN
easat-4052	374	39	and	and	CCONJ
easat-4052	374	40	meta	meta	ADJ
easat-4052	374	41	-	-	PUNCT
easat-4052	374	42	analysis	analysis	NOUN
easat-4052	374	43	.	.	PUNCT
easat-4052	375	1	stem	stem	NOUN
easat-4052	375	2	cell	cell	NOUN
easat-4052	375	3	res	re	NOUN
easat-4052	375	4	ther	ther	ADV
easat-4052	375	5	.	.	PUNCT
easat-4052	376	1	2024;15(1):1–21	2024;15(1):1–21	NUM
easat-4052	376	2	.	.	PUNCT
easat-4052	377	1	https://doi.org/10.1186/s13287-024-04034-2	https://doi.org/10.1186/s13287-024-04034-2	NUM
easat-4052	378	1	[	[	X
easat-4052	378	2	34	34	NUM
easat-4052	378	3	]	]	X
easat-4052	378	4	lee	lee	PROPN
easat-4052	378	5	wy	wy	PROPN
easat-4052	378	6	wai	wai	PROPN
easat-4052	378	7	,	,	PUNCT
easat-4052	378	8	wang	wang	PROPN
easat-4052	378	9	b.	b.	PROPN
easat-4052	378	10	cartilage	cartilage	PROPN
easat-4052	378	11	repair	repair	NOUN
easat-4052	378	12	by	by	ADP
easat-4052	378	13	mesenchymal	mesenchymal	ADJ
easat-4052	378	14	stem	stem	NOUN
easat-4052	378	15	cells	cell	NOUN
easat-4052	378	16	:	:	PUNCT
easat-4052	378	17	clinical	clinical	ADJ
easat-4052	378	18	trial	trial	NOUN
easat-4052	378	19	update	update	NOUN
easat-4052	378	20	and	and	CCONJ
easat-4052	378	21	perspectives	perspective	NOUN
easat-4052	378	22	.	.	PUNCT
easat-4052	379	1	j	j	PROPN
easat-4052	379	2	orthop	orthop	PROPN
easat-4052	379	3	transl	transl	PROPN
easat-4052	379	4	.	.	PUNCT
easat-4052	380	1	2017;9(1):76–88	2017;9(1):76–88	NUM
easat-4052	380	2	.	.	PUNCT
easat-4052	381	1	https://doi.org/10.1016/j.jot.2017.03.005	https://doi.org/10.1016/j.jot.2017.03.005	PROPN
easat-4052	381	2	9604	9604	NUM
easat-4052	381	3	edelweiss	edelweiss	PROPN
easat-4052	381	4	applied	apply	VERB
easat-4052	381	5	science	science	NOUN
easat-4052	381	6	and	and	CCONJ
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easat-4052	381	8	issn	issn	PROPN
easat-4052	381	9	:	:	PUNCT
easat-4052	381	10	2576	2576	NUM
easat-4052	381	11	-	-	SYM
easat-4052	381	12	8484	8484	NUM
easat-4052	381	13	vol	vol	NOUN
easat-4052	381	14	.	.	PROPN
easat-4052	381	15	8	8	NUM
easat-4052	381	16	,	,	PUNCT
easat-4052	381	17	no	no	INTJ
easat-4052	381	18	.	.	NOUN
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easat-4052	382	2	:	:	SYM
easat-4052	382	3	9592	9592	NUM
easat-4052	382	4	-	-	SYM
easat-4052	382	5	9604	9604	NUM
easat-4052	382	6	,	,	PUNCT
easat-4052	382	7	2024	2024	NUM
easat-4052	382	8	doi	doi	NOUN
easat-4052	382	9	:	:	PUNCT
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easat-4052	383	2	2024	2024	NUM
easat-4052	383	3	by	by	ADP
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easat-4052	384	2	35	35	NUM
easat-4052	384	3	]	]	PUNCT
easat-4052	384	4	fellows	fellows	PROPN
easat-4052	384	5	cr	cr	PROPN
easat-4052	384	6	,	,	PUNCT
easat-4052	384	7	matta	matta	PROPN
easat-4052	384	8	c	c	PROPN
easat-4052	384	9	,	,	PUNCT
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easat-4052	384	12	,	,	PUNCT
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easat-4052	384	14	i	i	PROPN
easat-4052	384	15	m	m	PROPN
easat-4052	384	16	,	,	PUNCT
easat-4052	384	17	mobasheri	mobasheri	PROPN
easat-4052	384	18	a.	a.	NOUN
easat-4052	384	19	adipose	adipose	PROPN
easat-4052	384	20	,	,	PUNCT
easat-4052	384	21	bone	bone	NOUN
easat-4052	384	22	marrow	marrow	NOUN
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easat-4052	384	26	-	-	PUNCT
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easat-4052	384	28	mesenchymal	mesenchymal	NOUN
easat-4052	384	29	stem	stem	NOUN
easat-4052	384	30	cells	cell	NOUN
easat-4052	384	31	for	for	ADP
easat-4052	384	32	cartilage	cartilage	NOUN
easat-4052	384	33	repair	repair	NOUN
easat-4052	384	34	.	.	PUNCT
easat-4052	385	1	front	front	ADJ
easat-4052	385	2	genet	genet	PROPN
easat-4052	385	3	.	.	PUNCT
easat-4052	386	1	2016;7(dec):1–20	2016;7(dec):1–20	NUM
easat-4052	386	2	.	.	PUNCT
easat-4052	387	1	https://doi.org/10.3389/fgene.2016.00213	https://doi.org/10.3389/fgene.2016.00213	PROPN
easat-4052	388	1	[	[	X
easat-4052	388	2	36	36	NUM
easat-4052	388	3	]	]	X
easat-4052	388	4	zha	zha	PROPN
easat-4052	388	5	k	k	PROPN
easat-4052	388	6	,	,	PUNCT
easat-4052	388	7	sun	sun	PROPN
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easat-4052	388	9	,	,	PUNCT
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easat-4052	388	13	chen	chen	PROPN
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easat-4052	388	15	,	,	PUNCT
easat-4052	388	16	gao	gao	PROPN
easat-4052	388	17	c	c	PROPN
easat-4052	388	18	,	,	PUNCT
easat-4052	388	19	fu	fu	PROPN
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easat-4052	388	21	,	,	PUNCT
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easat-4052	388	23	al	al	PROPN
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easat-4052	388	28	for	for	ADP
easat-4052	388	29	enhancing	enhance	VERB
easat-4052	388	30	chondrogenic	chondrogenic	ADJ
easat-4052	388	31	differentiation	differentiation	NOUN
easat-4052	388	32	of	of	ADP
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easat-4052	388	34	:	:	PUNCT
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easat-4052	388	36	on	on	ADP
easat-4052	388	37	msc	msc	NOUN
easat-4052	388	38	-	-	PUNCT
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easat-4052	388	41	for	for	ADP
easat-4052	388	42	cartilage	cartilage	NOUN
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easat-4052	388	44	.	.	PUNCT
easat-4052	389	1	stem	stem	NOUN
easat-4052	389	2	cells	cell	NOUN
easat-4052	389	3	int	int	NOUN
easat-4052	389	4	.	.	PUNCT
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easat-4052	390	2	.	.	PUNCT
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easat-4052	392	3	]	]	X
easat-4052	392	4	fu	fu	PROPN
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easat-4052	392	6	,	,	PUNCT
easat-4052	392	7	wang	wang	PROPN
easat-4052	392	8	x	x	PROPN
easat-4052	392	9	,	,	PUNCT
easat-4052	392	10	yang	yang	PROPN
easat-4052	392	11	m	m	PROPN
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easat-4052	392	13	chen	chen	PROPN
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easat-4052	393	4	.	.	PUNCT
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easat-4052	394	2	.	.	PUNCT
easat-4052	395	1	https://doi.org/10.3389/fbioe.2021.812383	https://doi.org/10.3389/fbioe.2021.812383	PROPN
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easat-4052	396	35	.	.	PUNCT
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easat-4052	397	2	j	j	PROPN
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easat-4052	397	5	.	.	PUNCT
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easat-4052	398	2	.	.	PUNCT
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easat-4052	400	8	-	-	PUNCT
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easat-4052	400	10	and	and	CCONJ
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easat-4052	400	13	in	in	ADP
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easat-4052	400	15	and	and	CCONJ
easat-4052	400	16	cartilage	cartilage	NOUN
easat-4052	400	17	development	development	NOUN
easat-4052	400	18	,	,	PUNCT
easat-4052	400	19	homeostasis	homeostasis	NOUN
easat-4052	400	20	and	and	CCONJ
easat-4052	400	21	disease	disease	NOUN
easat-4052	400	22	.	.	PUNCT
easat-4052	401	1	cell	cell	NOUN
easat-4052	401	2	res	re	NOUN
easat-4052	401	3	.	.	PUNCT
easat-4052	402	1	2024;34(2):101–23	2024;34(2):101–23	NUM
easat-4052	402	2	.	.	PUNCT
easat-4052	403	1	https://doi.org/10.1038/s41422-02300918-9	https://doi.org/10.1038/s41422-02300918-9	PROPN
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easat-4052	404	2	40	40	NUM
easat-4052	404	3	]	]	PUNCT
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easat-4052	404	13	jeon	jeon	PROPN
easat-4052	404	14	h	h	PROPN
easat-4052	404	15	,	,	PUNCT
easat-4052	404	16	han	han	PROPN
easat-4052	404	17	hs	hs	PROPN
easat-4052	404	18	.	.	PROPN
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easat-4052	404	20	tissue	tissue	NOUN
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easat-4052	404	22	and	and	CCONJ
easat-4052	404	23	regenerative	regenerative	ADJ
easat-4052	404	24	medicine	medicine	NOUN
easat-4052	404	25	to	to	PART
easat-4052	404	26	treat	treat	VERB
easat-4052	404	27	musculoskeletal	musculoskeletal	ADJ
easat-4052	404	28	disorders	disorder	NOUN
easat-4052	404	29	in	in	ADP
easat-4052	404	30	bone	bone	NOUN
easat-4052	404	31	and	and	CCONJ
easat-4052	404	32	muscle	muscle	NOUN
easat-4052	404	33	.	.	PUNCT
easat-4052	404	34	bioact	bioact	PROPN
easat-4052	404	35	mater	mater	PROPN
easat-4052	404	36	.	.	PUNCT
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easat-4052	405	2	.	.	PUNCT
easat-4052	406	1	https://doi.org/10.1016/j.bioactmat.2024.06.022	https://doi.org/10.1016/j.bioactmat.2024.06.022	PROPN
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easat-4052	407	2	41	41	NUM
easat-4052	407	3	]	]	PUNCT
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easat-4052	407	9	,	,	PUNCT
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easat-4052	407	11	blg	blg	PROPN
easat-4052	407	12	,	,	PUNCT
easat-4052	407	13	shinde	shinde	PROPN
easat-4052	407	14	ar	ar	PROPN
easat-4052	407	15	,	,	PUNCT
easat-4052	407	16	arakelians	arakelians	PROPN
easat-4052	407	17	arl	arl	PROPN
easat-4052	407	18	,	,	PUNCT
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easat-4052	407	28	bone	bone	NOUN
easat-4052	407	29	tissue	tissue	NOUN
easat-4052	407	30	regeneration	regeneration	NOUN
easat-4052	407	31	:	:	PUNCT
easat-4052	407	32	a	a	DET
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easat-4052	407	34	review	review	NOUN
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easat-4052	407	36	materials	material	NOUN
easat-4052	407	37	,	,	PUNCT
easat-4052	407	38	methods	method	NOUN
easat-4052	407	39	,	,	PUNCT
easat-4052	407	40	and	and	CCONJ
easat-4052	407	41	future	future	ADJ
easat-4052	407	42	directions	direction	NOUN
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