id	sid	tid	token	lemma	pos
easat-4310	1	1	edelweiss	edelweiss	PROPN
easat-4310	1	2	applied	apply	VERB
easat-4310	1	3	science	science	NOUN
easat-4310	1	4	and	and	CCONJ
easat-4310	1	5	technology	technology	NOUN
easat-4310	1	6	issn	issn	PROPN
easat-4310	1	7	:	:	PUNCT
easat-4310	1	8	2576	2576	NUM
easat-4310	1	9	-	-	SYM
easat-4310	1	10	8484	8484	NUM
easat-4310	1	11	vol	vol	NOUN
easat-4310	1	12	.	.	PROPN
easat-4310	2	1	9	9	NUM
easat-4310	2	2	,	,	PUNCT
easat-4310	2	3	no	no	INTJ
easat-4310	2	4	.	.	NOUN
easat-4310	2	5	1	1	NUM
easat-4310	2	6	,	,	PUNCT
easat-4310	2	7	1078	1078	NUM
easat-4310	2	8	-	-	SYM
easat-4310	2	9	1085	1085	NUM
easat-4310	2	10	2025	2025	NUM
easat-4310	2	11	publisher	publisher	NOUN
easat-4310	2	12	:	:	PUNCT
easat-4310	2	13	learning	learn	VERB
easat-4310	2	14	gate	gate	NOUN
easat-4310	2	15	doi	doi	PROPN
easat-4310	2	16	:	:	PUNCT
easat-4310	2	17	10.55214/25768484.v9i1.4310	10.55214/25768484.v9i1.4310	NUM
easat-4310	2	18	©	©	PROPN
easat-4310	2	19	2025	2025	NUM
easat-4310	2	20	by	by	ADP
easat-4310	2	21	the	the	DET
easat-4310	2	22	authors	author	NOUN
easat-4310	2	23	;	;	PUNCT
easat-4310	2	24	licensee	licensee	PROPN
easat-4310	2	25	learning	learning	NOUN
easat-4310	2	26	gate	gate	NOUN
easat-4310	3	1	©	©	PROPN
easat-4310	3	2	2025	2025	NUM
easat-4310	3	3	by	by	ADP
easat-4310	3	4	the	the	DET
easat-4310	3	5	authors	author	NOUN
easat-4310	3	6	;	;	PUNCT
easat-4310	3	7	licensee	licensee	PROPN
easat-4310	3	8	learning	learning	NOUN
easat-4310	3	9	gate	gate	NOUN
easat-4310	3	10	history	history	NOUN
easat-4310	3	11	:	:	PUNCT
easat-4310	3	12	received	receive	VERB
easat-4310	3	13	:	:	PUNCT
easat-4310	3	14	29	29	NUM
easat-4310	3	15	november	november	PROPN
easat-4310	3	16	2024	2024	NUM
easat-4310	3	17	;	;	PUNCT
easat-4310	3	18	revised	revise	VERB
easat-4310	3	19	:	:	PUNCT
easat-4310	3	20	8	8	NUM
easat-4310	3	21	january	january	PROPN
easat-4310	3	22	2024	2024	NUM
easat-4310	3	23	;	;	PUNCT
easat-4310	3	24	accepted	accept	VERB
easat-4310	3	25	:	:	PUNCT
easat-4310	3	26	15	15	NUM
easat-4310	3	27	january	january	NOUN
easat-4310	3	28	2025	2025	NUM
easat-4310	3	29	;	;	PUNCT
easat-4310	3	30	published	publish	VERB
easat-4310	3	31	:	:	PUNCT
easat-4310	3	32	17	17	NUM
easat-4310	3	33	january	january	NOUN
easat-4310	3	34	2025	2025	NUM
easat-4310	3	35	*	*	PUNCT
easat-4310	3	36	correspondence	correspondence	NOUN
easat-4310	3	37	:	:	PUNCT
easat-4310	3	38	alpha-f-a@fk.unair.ac.id	alpha-f-a@fk.unair.ac.id	PROPN
easat-4310	4	1	the	the	DET
easat-4310	4	2	effect	effect	NOUN
easat-4310	4	3	of	of	ADP
easat-4310	4	4	high	high	ADJ
easat-4310	4	5	-	-	PUNCT
easat-4310	4	6	dose	dose	NOUN
easat-4310	4	7	methotrexate	methotrexate	NOUN
easat-4310	4	8	chemotherapy	chemotherapy	NOUN
easat-4310	4	9	on	on	ADP
easat-4310	4	10	citrulline	citrulline	NOUN
easat-4310	4	11	level	level	NOUN
easat-4310	4	12	to	to	ADP
easat-4310	4	13	gastrointestinal	gastrointestinal	ADJ
easat-4310	4	14	mucositis	mucositis	NOUN
easat-4310	4	15	cases	case	NOUN
easat-4310	4	16	in	in	ADP
easat-4310	4	17	children	child	NOUN
easat-4310	4	18	with	with	ADP
easat-4310	4	19	acute	acute	ADJ
easat-4310	4	20	lymphoblastic	lymphoblastic	ADJ
easat-4310	4	21	leukemia	leukemia	NOUN
easat-4310	4	22	during	during	ADP
easat-4310	4	23	the	the	DET
easat-4310	4	24	consolidation	consolidation	NOUN
easat-4310	4	25	phase	phase	NOUN
easat-4310	4	26	susanti	susanti	VERB
easat-4310	5	1	rahmayani1,2	rahmayani1,2	PROPN
easat-4310	5	2	,	,	PUNCT
easat-4310	5	3	alpha	alpha	NOUN
easat-4310	5	4	fardah	fardah	NOUN
easat-4310	5	5	athiyyah1,2	athiyyah1,2	PROPN
easat-4310	5	6	*	*	PROPN
easat-4310	5	7	,	,	PUNCT
easat-4310	5	8	i.g.m	i.g.m	PROPN
easat-4310	5	9	reza	reza	PROPN
easat-4310	5	10	gunadi	gunadi	PROPN
easat-4310	5	11	ranuh1,2	ranuh1,2	PROPN
easat-4310	5	12	,	,	PUNCT
easat-4310	5	13	andy	andy	PROPN
easat-4310	5	14	darma1,2	darma1,2	PROPN
easat-4310	5	15	,	,	PUNCT
easat-4310	5	16	khadijah	khadijah	PROPN
easat-4310	5	17	rizky	rizky	PROPN
easat-4310	5	18	sumitro1,2	sumitro1,2	PROPN
easat-4310	5	19	,	,	PUNCT
easat-4310	5	20	mia	mia	PROPN
easat-4310	5	21	ratwita	ratwita	VERB
easat-4310	5	22	andarsini1,2	andarsini1,2	PROPN
easat-4310	5	23	,	,	PUNCT
easat-4310	5	24	subijanto	subijanto	NOUN
easat-4310	5	25	marto	marto	PROPN
easat-4310	5	26	sudarmo1,2	sudarmo1,2	PROPN
easat-4310	5	27	1department	1department	NUM
easat-4310	5	28	of	of	ADP
easat-4310	5	29	child	child	NOUN
easat-4310	5	30	health	health	NOUN
easat-4310	5	31	,	,	PUNCT
easat-4310	5	32	faculty	faculty	NOUN
easat-4310	5	33	of	of	ADP
easat-4310	5	34	medicine	medicine	NOUN
easat-4310	5	35	,	,	PUNCT
easat-4310	5	36	universitas	universita	NOUN
easat-4310	5	37	airlangga	airlangga	NOUN
easat-4310	5	38	,	,	PUNCT
easat-4310	5	39	surabaya	surabaya	PROPN
easat-4310	5	40	,	,	PUNCT
easat-4310	5	41	indonesia	indonesia	PROPN
easat-4310	5	42	;	;	PUNCT
easat-4310	5	43	alpha-f-a@fk.unair.ac.id	alpha-f-a@fk.unair.ac.id	PROPN
easat-4310	5	44	(	(	PUNCT
easat-4310	5	45	a.f.a	a.f.a	PROPN
easat-4310	5	46	.	.	PUNCT
easat-4310	5	47	)	)	PUNCT
easat-4310	5	48	.	.	PUNCT
easat-4310	6	1	2dapartment	2dapartment	NUM
easat-4310	6	2	of	of	ADP
easat-4310	6	3	child	child	NOUN
easat-4310	6	4	health	health	PROPN
easat-4310	6	5	,	,	PUNCT
easat-4310	6	6	dr	dr	PROPN
easat-4310	6	7	.	.	PROPN
easat-4310	6	8	soetomo	soetomo	PROPN
easat-4310	6	9	general	general	PROPN
easat-4310	6	10	academic	academic	ADJ
easat-4310	6	11	hospital	hospital	NOUN
easat-4310	6	12	,	,	PUNCT
easat-4310	6	13	surabaya	surabaya	PROPN
easat-4310	6	14	,	,	PUNCT
easat-4310	6	15	indonesia	indonesia	PROPN
easat-4310	6	16	.	.	PUNCT
easat-4310	7	1	abstract	abstract	ADJ
easat-4310	7	2	:	:	PUNCT
easat-4310	7	3	acute	acute	ADJ
easat-4310	7	4	lymphoblastic	lymphoblastic	ADJ
easat-4310	7	5	leukemia	leukemia	NOUN
easat-4310	7	6	(	(	PUNCT
easat-4310	7	7	all	all	PRON
easat-4310	7	8	)	)	PUNCT
easat-4310	7	9	is	be	AUX
easat-4310	7	10	the	the	DET
easat-4310	7	11	most	most	ADV
easat-4310	7	12	common	common	ADJ
easat-4310	7	13	pediatric	pediatric	ADJ
easat-4310	7	14	malignancy	malignancy	NOUN
easat-4310	7	15	,	,	PUNCT
easat-4310	7	16	with	with	ADP
easat-4310	7	17	survival	survival	NOUN
easat-4310	7	18	rates	rate	NOUN
easat-4310	7	19	exceeding	exceed	VERB
easat-4310	7	20	90	90	NUM
easat-4310	7	21	%	%	NOUN
easat-4310	7	22	due	due	ADP
easat-4310	7	23	to	to	ADP
easat-4310	7	24	advancements	advancement	NOUN
easat-4310	7	25	in	in	ADP
easat-4310	7	26	chemotherapy	chemotherapy	NOUN
easat-4310	7	27	,	,	PUNCT
easat-4310	7	28	including	include	VERB
easat-4310	7	29	high	high	ADJ
easat-4310	7	30	-	-	PUNCT
easat-4310	7	31	dose	dose	NOUN
easat-4310	7	32	methotrexate	methotrexate	NOUN
easat-4310	7	33	(	(	PUNCT
easat-4310	7	34	hd	hd	NOUN
easat-4310	7	35	-	-	PUNCT
easat-4310	7	36	mtx	mtx	NOUN
easat-4310	7	37	)	)	PUNCT
easat-4310	7	38	.	.	PUNCT
easat-4310	8	1	however	however	ADV
easat-4310	8	2	,	,	PUNCT
easat-4310	8	3	gastrointestinal	gastrointestinal	ADJ
easat-4310	8	4	(	(	PUNCT
easat-4310	8	5	gi	gi	INTJ
easat-4310	8	6	)	)	PUNCT
easat-4310	8	7	mucositis	mucositis	NOUN
easat-4310	8	8	remains	remain	VERB
easat-4310	8	9	a	a	DET
easat-4310	8	10	significant	significant	ADJ
easat-4310	8	11	complication	complication	NOUN
easat-4310	8	12	,	,	PUNCT
easat-4310	8	13	impairing	impair	VERB
easat-4310	8	14	treatment	treatment	NOUN
easat-4310	8	15	continuity	continuity	NOUN
easat-4310	8	16	and	and	CCONJ
easat-4310	8	17	quality	quality	NOUN
easat-4310	8	18	of	of	ADP
easat-4310	8	19	life	life	NOUN
easat-4310	8	20	.	.	PUNCT
easat-4310	9	1	citrulline	citrulline	NOUN
easat-4310	9	2	,	,	PUNCT
easat-4310	9	3	a	a	DET
easat-4310	9	4	biomarker	biomarker	NOUN
easat-4310	9	5	synthesized	synthesize	VERB
easat-4310	9	6	in	in	ADP
easat-4310	9	7	enterocytes	enterocyte	NOUN
easat-4310	9	8	,	,	PUNCT
easat-4310	9	9	reflects	reflect	VERB
easat-4310	9	10	intestinal	intestinal	ADJ
easat-4310	9	11	integrity	integrity	NOUN
easat-4310	9	12	and	and	CCONJ
easat-4310	9	13	offers	offer	VERB
easat-4310	9	14	a	a	DET
easat-4310	9	15	non	non	ADJ
easat-4310	9	16	-	-	ADJ
easat-4310	9	17	invasive	invasive	ADJ
easat-4310	9	18	alternative	alternative	NOUN
easat-4310	9	19	for	for	ADP
easat-4310	9	20	monitoring	monitor	VERB
easat-4310	9	21	mucosal	mucosal	ADJ
easat-4310	9	22	damage	damage	NOUN
easat-4310	9	23	.	.	PUNCT
easat-4310	10	1	this	this	DET
easat-4310	10	2	study	study	NOUN
easat-4310	10	3	aimed	aim	VERB
easat-4310	10	4	to	to	PART
easat-4310	10	5	evaluate	evaluate	VERB
easat-4310	10	6	citrulline	citrulline	NOUN
easat-4310	10	7	dynamics	dynamic	NOUN
easat-4310	10	8	in	in	ADP
easat-4310	10	9	children	child	NOUN
easat-4310	10	10	with	with	ADP
easat-4310	10	11	all	all	PRON
easat-4310	10	12	undergoing	undergo	VERB
easat-4310	10	13	hd	hd	NOUN
easat-4310	10	14	-	-	PUNCT
easat-4310	10	15	mtx	mtx	NOUN
easat-4310	10	16	chemotherapy	chemotherapy	NOUN
easat-4310	10	17	during	during	ADP
easat-4310	10	18	the	the	DET
easat-4310	10	19	consolidation	consolidation	NOUN
easat-4310	10	20	phase	phase	NOUN
easat-4310	10	21	.	.	PUNCT
easat-4310	11	1	this	this	DET
easat-4310	11	2	cross	cross	ADJ
easat-4310	11	3	-	-	ADJ
easat-4310	11	4	sectional	sectional	ADJ
easat-4310	11	5	study	study	NOUN
easat-4310	11	6	included	include	VERB
easat-4310	11	7	34	34	NUM
easat-4310	11	8	pediatric	pediatric	ADJ
easat-4310	11	9	all	all	DET
easat-4310	11	10	patients	patient	NOUN
easat-4310	11	11	in	in	ADP
easat-4310	11	12	consolidation	consolidation	NOUN
easat-4310	11	13	phase	phase	NOUN
easat-4310	11	14	.	.	PUNCT
easat-4310	12	1	serum	serum	PROPN
easat-4310	12	2	citrulline	citrulline	NOUN
easat-4310	12	3	levels	level	NOUN
easat-4310	12	4	were	be	AUX
easat-4310	12	5	measured	measure	VERB
easat-4310	12	6	preand	preand	ADJ
easat-4310	12	7	post	post	ADJ
easat-4310	12	8	-	-	ADJ
easat-4310	12	9	hd	hd	ADJ
easat-4310	12	10	-	-	PUNCT
easat-4310	12	11	mtx	mtx	NOUN
easat-4310	12	12	chemotherapy	chemotherapy	NOUN
easat-4310	12	13	using	use	VERB
easat-4310	12	14	high	high	ADJ
easat-4310	12	15	-	-	PUNCT
easat-4310	12	16	performance	performance	NOUN
easat-4310	12	17	liquid	liquid	ADJ
easat-4310	12	18	chromatography	chromatography	NOUN
easat-4310	12	19	.	.	PUNCT
easat-4310	13	1	mucositis	mucositis	NOUN
easat-4310	13	2	severity	severity	NOUN
easat-4310	13	3	was	be	AUX
easat-4310	13	4	assessed	assess	VERB
easat-4310	13	5	using	use	VERB
easat-4310	13	6	the	the	DET
easat-4310	13	7	national	national	PROPN
easat-4310	13	8	cancer	cancer	PROPN
easat-4310	13	9	institute	institute	PROPN
easat-4310	13	10	common	common	ADJ
easat-4310	13	11	terminology	terminology	NOUN
easat-4310	13	12	criteria	criterion	NOUN
easat-4310	13	13	.	.	PUNCT
easat-4310	14	1	data	datum	NOUN
easat-4310	14	2	analysis	analysis	NOUN
easat-4310	14	3	involved	involve	VERB
easat-4310	14	4	paired	pair	VERB
easat-4310	14	5	t	t	NOUN
easat-4310	14	6	-	-	PUNCT
easat-4310	14	7	tests	test	NOUN
easat-4310	14	8	and	and	CCONJ
easat-4310	14	9	subgroup	subgroup	NOUN
easat-4310	14	10	comparisons	comparison	NOUN
easat-4310	14	11	by	by	ADP
easat-4310	14	12	risk	risk	NOUN
easat-4310	14	13	stratification	stratification	NOUN
easat-4310	14	14	(	(	PUNCT
easat-4310	14	15	standard	standard	ADJ
easat-4310	14	16	risk	risk	NOUN
easat-4310	15	1	[	[	X
easat-4310	15	2	sr	sr	X
easat-4310	15	3	]	]	X
easat-4310	15	4	,	,	PUNCT
easat-4310	15	5	high	high	ADJ
easat-4310	15	6	risk	risk	NOUN
easat-4310	15	7	[	[	X
easat-4310	15	8	hr	hr	NOUN
easat-4310	15	9	]	]	X
easat-4310	15	10	)	)	PUNCT
easat-4310	15	11	and	and	CCONJ
easat-4310	15	12	mucositis	mucositis	PROPN
easat-4310	15	13	grades	grade	NOUN
easat-4310	15	14	.	.	PUNCT
easat-4310	16	1	overall	overall	ADV
easat-4310	16	2	,	,	PUNCT
easat-4310	16	3	no	no	DET
easat-4310	16	4	significant	significant	ADJ
easat-4310	16	5	changes	change	NOUN
easat-4310	16	6	in	in	ADP
easat-4310	16	7	serum	serum	NOUN
easat-4310	16	8	citrulline	citrulline	NOUN
easat-4310	16	9	levels	level	NOUN
easat-4310	16	10	were	be	AUX
easat-4310	16	11	observed	observe	VERB
easat-4310	16	12	post	post	ADJ
easat-4310	16	13	-	-	NOUN
easat-4310	16	14	chemotherapy	chemotherapy	NOUN
easat-4310	16	15	.	.	PUNCT
easat-4310	17	1	sr	sr	PROPN
easat-4310	17	2	patients	patient	NOUN
easat-4310	17	3	exhibited	exhibit	VERB
easat-4310	17	4	a	a	DET
easat-4310	17	5	significant	significant	ADJ
easat-4310	17	6	decline	decline	NOUN
easat-4310	17	7	in	in	ADP
easat-4310	17	8	citrulline	citrulline	NOUN
easat-4310	17	9	levels	level	NOUN
easat-4310	17	10	,	,	PUNCT
easat-4310	17	11	consistent	consistent	ADJ
easat-4310	17	12	with	with	ADP
easat-4310	17	13	mucosal	mucosal	NOUN
easat-4310	17	14	injury	injury	NOUN
easat-4310	17	15	.	.	PUNCT
easat-4310	18	1	conversely	conversely	ADV
easat-4310	18	2	,	,	PUNCT
easat-4310	18	3	hr	hr	NOUN
easat-4310	18	4	patients	patient	NOUN
easat-4310	18	5	demonstrated	demonstrate	VERB
easat-4310	18	6	an	an	DET
easat-4310	18	7	unexpected	unexpected	ADJ
easat-4310	18	8	increase	increase	NOUN
easat-4310	18	9	in	in	ADP
easat-4310	18	10	citrulline	citrulline	NOUN
easat-4310	18	11	,	,	PUNCT
easat-4310	18	12	potentially	potentially	ADV
easat-4310	18	13	due	due	ADJ
easat-4310	18	14	to	to	ADP
easat-4310	18	15	compensatory	compensatory	ADJ
easat-4310	18	16	enterocyte	enterocyte	NOUN
easat-4310	18	17	responses	response	NOUN
easat-4310	18	18	or	or	CCONJ
easat-4310	18	19	altered	alter	VERB
easat-4310	18	20	metabolism	metabolism	NOUN
easat-4310	18	21	.	.	PUNCT
easat-4310	19	1	grade	grade	NOUN
easat-4310	19	2	1	1	NUM
easat-4310	19	3	mucositis	mucositis	NOUN
easat-4310	19	4	patients	patient	NOUN
easat-4310	19	5	showed	show	VERB
easat-4310	19	6	increased	increase	VERB
easat-4310	19	7	citrulline	citrulline	NOUN
easat-4310	19	8	levels	level	NOUN
easat-4310	19	9	,	,	PUNCT
easat-4310	19	10	indicating	indicate	VERB
easat-4310	19	11	early	early	ADJ
easat-4310	19	12	recovery	recovery	NOUN
easat-4310	19	13	,	,	PUNCT
easat-4310	19	14	while	while	SCONJ
easat-4310	19	15	grade	grade	NOUN
easat-4310	19	16	2	2	NUM
easat-4310	19	17	mucositis	mucositis	NOUN
easat-4310	19	18	patients	patient	NOUN
easat-4310	19	19	showed	show	VERB
easat-4310	19	20	no	no	DET
easat-4310	19	21	significant	significant	ADJ
easat-4310	19	22	changes	change	NOUN
easat-4310	19	23	,	,	PUNCT
easat-4310	19	24	reflecting	reflect	VERB
easat-4310	19	25	sustained	sustained	ADJ
easat-4310	19	26	injury	injury	NOUN
easat-4310	19	27	.	.	PUNCT
easat-4310	20	1	citrulline	citrulline	NOUN
easat-4310	20	2	is	be	AUX
easat-4310	20	3	a	a	DET
easat-4310	20	4	promising	promising	ADJ
easat-4310	20	5	biomarker	biomarker	NOUN
easat-4310	20	6	for	for	ADP
easat-4310	20	7	monitoring	monitor	VERB
easat-4310	20	8	chemotherapy	chemotherapy	NOUN
easat-4310	20	9	-	-	VERB
easat-4310	20	10	induced	induced	ADJ
easat-4310	20	11	gi	gi	ADP
easat-4310	20	12	mucositis	mucositis	PROPN
easat-4310	20	13	in	in	ADP
easat-4310	20	14	pediatric	pediatric	ADJ
easat-4310	20	15	all	all	DET
easat-4310	20	16	patients	patient	NOUN
easat-4310	20	17	.	.	PUNCT
easat-4310	21	1	its	its	PRON
easat-4310	21	2	non	non	ADJ
easat-4310	21	3	-	-	ADJ
easat-4310	21	4	invasive	invasive	ADJ
easat-4310	21	5	measurement	measurement	NOUN
easat-4310	21	6	and	and	CCONJ
easat-4310	21	7	correlation	correlation	NOUN
easat-4310	21	8	with	with	ADP
easat-4310	21	9	mucosal	mucosal	ADJ
easat-4310	21	10	health	health	NOUN
easat-4310	21	11	highlight	highlight	VERB
easat-4310	21	12	its	its	PRON
easat-4310	21	13	potential	potential	NOUN
easat-4310	21	14	for	for	ADP
easat-4310	21	15	improving	improve	VERB
easat-4310	21	16	personalized	personalized	ADJ
easat-4310	21	17	care	care	NOUN
easat-4310	21	18	.	.	PUNCT
easat-4310	22	1	further	further	ADJ
easat-4310	22	2	validation	validation	NOUN
easat-4310	22	3	in	in	ADP
easat-4310	22	4	diverse	diverse	ADJ
easat-4310	22	5	populations	population	NOUN
easat-4310	22	6	is	be	AUX
easat-4310	22	7	required	require	VERB
easat-4310	22	8	to	to	PART
easat-4310	22	9	optimize	optimize	VERB
easat-4310	22	10	its	its	PRON
easat-4310	22	11	clinical	clinical	ADJ
easat-4310	22	12	application	application	NOUN
easat-4310	22	13	.	.	PUNCT
easat-4310	23	1	keywords	keyword	NOUN
easat-4310	23	2	:	:	PUNCT
easat-4310	23	3	biomarker	biomarker	NOUN
easat-4310	23	4	,	,	PUNCT
easat-4310	23	5	chemotherapy	chemotherapy	NOUN
easat-4310	23	6	,	,	PUNCT
easat-4310	23	7	citrulline	citrulline	NOUN
easat-4310	23	8	,	,	PUNCT
easat-4310	23	9	gastrointestinal	gastrointestinal	ADJ
easat-4310	23	10	,	,	PUNCT
easat-4310	23	11	mucositis	mucositis	NOUN
easat-4310	23	12	,	,	PUNCT
easat-4310	23	13	pediatrics	pediatric	NOUN
easat-4310	23	14	.	.	PUNCT
easat-4310	24	1	1	1	X
easat-4310	24	2	.	.	X
easat-4310	24	3	introduction	introduction	NOUN
easat-4310	24	4	acute	acute	NOUN
easat-4310	24	5	lymphoblastic	lymphoblastic	ADJ
easat-4310	24	6	leukemia	leukemia	NOUN
easat-4310	24	7	(	(	PUNCT
easat-4310	24	8	all	all	PRON
easat-4310	24	9	)	)	PUNCT
easat-4310	24	10	is	be	AUX
easat-4310	24	11	the	the	DET
easat-4310	24	12	most	most	ADV
easat-4310	24	13	prevalent	prevalent	ADJ
easat-4310	24	14	pediatric	pediatric	ADJ
easat-4310	24	15	malignancy	malignancy	NOUN
easat-4310	24	16	,	,	PUNCT
easat-4310	24	17	accounting	account	VERB
easat-4310	24	18	for	for	ADP
easat-4310	24	19	approximately	approximately	ADV
easat-4310	24	20	25	25	NUM
easat-4310	24	21	%	%	NOUN
easat-4310	24	22	of	of	ADP
easat-4310	24	23	all	all	DET
easat-4310	24	24	childhood	childhood	NOUN
easat-4310	24	25	cancers	cancer	NOUN
easat-4310	24	26	globally	globally	ADV
easat-4310	25	1	[	[	X
easat-4310	25	2	1	1	NUM
easat-4310	25	3	]	]	PUNCT
easat-4310	25	4	.	.	PUNCT
easat-4310	26	1	advances	advance	NOUN
easat-4310	26	2	in	in	ADP
easat-4310	26	3	treatment	treatment	NOUN
easat-4310	26	4	,	,	PUNCT
easat-4310	26	5	including	include	VERB
easat-4310	26	6	high	high	ADJ
easat-4310	26	7	-	-	PUNCT
easat-4310	26	8	dose	dose	NOUN
easat-4310	26	9	methotrexate	methotrexate	NOUN
easat-4310	26	10	(	(	PUNCT
easat-4310	26	11	hd	hd	NOUN
easat-4310	26	12	-	-	PUNCT
easat-4310	26	13	mtx	mtx	NOUN
easat-4310	26	14	)	)	PUNCT
easat-4310	26	15	chemotherapy	chemotherapy	NOUN
easat-4310	26	16	,	,	PUNCT
easat-4310	26	17	have	have	AUX
easat-4310	26	18	led	lead	VERB
easat-4310	26	19	to	to	ADP
easat-4310	26	20	a	a	DET
easat-4310	26	21	significant	significant	ADJ
easat-4310	26	22	improvement	improvement	NOUN
easat-4310	26	23	in	in	ADP
easat-4310	26	24	survival	survival	NOUN
easat-4310	26	25	rates	rate	NOUN
easat-4310	26	26	,	,	PUNCT
easat-4310	26	27	with	with	ADP
easat-4310	26	28	contemporary	contemporary	ADJ
easat-4310	26	29	survival	survival	NOUN
easat-4310	26	30	exceeding	exceed	VERB
easat-4310	26	31	90	90	NUM
easat-4310	26	32	%	%	NOUN
easat-4310	26	33	in	in	ADP
easat-4310	26	34	developed	develop	VERB
easat-4310	26	35	nations	nation	NOUN
easat-4310	26	36	[	[	X
easat-4310	26	37	2	2	NUM
easat-4310	26	38	]	]	PUNCT
easat-4310	26	39	.	.	PUNCT
easat-4310	27	1	however	however	ADV
easat-4310	27	2	,	,	PUNCT
easat-4310	27	3	these	these	DET
easat-4310	27	4	intensive	intensive	ADJ
easat-4310	27	5	regimens	regimen	NOUN
easat-4310	27	6	are	be	AUX
easat-4310	27	7	frequently	frequently	ADV
easat-4310	27	8	associated	associate	VERB
easat-4310	27	9	with	with	ADP
easat-4310	27	10	severe	severe	ADJ
easat-4310	27	11	complications	complication	NOUN
easat-4310	27	12	,	,	PUNCT
easat-4310	27	13	such	such	ADJ
easat-4310	27	14	as	as	ADP
easat-4310	27	15	gastrointestinal	gastrointestinal	ADJ
easat-4310	27	16	(	(	PUNCT
easat-4310	27	17	gi	gi	INTJ
easat-4310	27	18	)	)	PUNCT
easat-4310	27	19	mucositis	mucositis	NOUN
easat-4310	27	20	.	.	PUNCT
easat-4310	28	1	this	this	DET
easat-4310	28	2	condition	condition	NOUN
easat-4310	28	3	results	result	VERB
easat-4310	28	4	from	from	ADP
easat-4310	28	5	the	the	DET
easat-4310	28	6	direct	direct	ADJ
easat-4310	28	7	toxic	toxic	ADJ
easat-4310	28	8	effects	effect	NOUN
easat-4310	28	9	of	of	ADP
easat-4310	28	10	chemotherapy	chemotherapy	NOUN
easat-4310	28	11	on	on	ADP
easat-4310	28	12	the	the	DET
easat-4310	28	13	rapidly	rapidly	ADV
easat-4310	28	14	dividing	divide	VERB
easat-4310	28	15	epithelial	epithelial	ADJ
easat-4310	28	16	cells	cell	NOUN
easat-4310	28	17	lining	line	VERB
easat-4310	28	18	the	the	DET
easat-4310	28	19	gi	gi	NOUN
easat-4310	28	20	tract	tract	NOUN
easat-4310	28	21	,	,	PUNCT
easat-4310	28	22	leading	lead	VERB
easat-4310	28	23	to	to	ADP
easat-4310	28	24	mucosal	mucosal	ADJ
easat-4310	28	25	damage	damage	NOUN
easat-4310	28	26	,	,	PUNCT
easat-4310	28	27	nutrient	nutrient	ADJ
easat-4310	28	28	malabsorption	malabsorption	NOUN
easat-4310	28	29	,	,	PUNCT
easat-4310	28	30	and	and	CCONJ
easat-4310	28	31	an	an	DET
easat-4310	28	32	increased	increase	VERB
easat-4310	28	33	risk	risk	NOUN
easat-4310	28	34	of	of	ADP
easat-4310	28	35	systemic	systemic	ADJ
easat-4310	28	36	infections	infection	NOUN
easat-4310	28	37	[	[	X
easat-4310	28	38	3	3	NUM
easat-4310	28	39	]	]	PUNCT
easat-4310	28	40	.	.	PUNCT
easat-4310	29	1	these	these	DET
easat-4310	29	2	effects	effect	NOUN
easat-4310	29	3	not	not	PART
easat-4310	29	4	only	only	ADV
easat-4310	29	5	impair	impair	VERB
easat-4310	29	6	quality	quality	NOUN
easat-4310	29	7	of	of	ADP
easat-4310	29	8	life	life	NOUN
easat-4310	29	9	but	but	CCONJ
easat-4310	29	10	also	also	ADV
easat-4310	29	11	compromise	compromise	VERB
easat-4310	29	12	the	the	DET
easat-4310	29	13	continuity	continuity	NOUN
easat-4310	29	14	of	of	ADP
easat-4310	29	15	treatment	treatment	NOUN
easat-4310	29	16	,	,	PUNCT
easat-4310	30	1	https://orcid.org/0009-0006-7561-3890	https://orcid.org/0009-0006-7561-3890	NOUN
easat-4310	30	2	https://orcid.org/0000-0001-8839-3723	https://orcid.org/0000-0001-8839-3723	PROPN
easat-4310	30	3	https://orcid.org/0000-0002-4747-2449	https://orcid.org/0000-0002-4747-2449	PROPN
easat-4310	30	4	https://orcid.org/0000-0001-5107-5895	https://orcid.org/0000-0001-5107-5895	PROPN
easat-4310	30	5	https://orcid.org/0000-0001-8557-2400	https://orcid.org/0000-0001-8557-2400	VERB
easat-4310	30	6	https://orcid.org/0000-0003-1431-5137	https://orcid.org/0000-0003-1431-5137	PRON
easat-4310	30	7	https://orcid.org/0000-0002-8208-4417	https://orcid.org/0000-0002-8208-4417	ADJ
easat-4310	30	8	1079	1079	NUM
easat-4310	30	9	edelweiss	edelweiss	PROPN
easat-4310	30	10	applied	apply	VERB
easat-4310	30	11	science	science	NOUN
easat-4310	30	12	and	and	CCONJ
easat-4310	30	13	technology	technology	NOUN
easat-4310	30	14	issn	issn	PROPN
easat-4310	30	15	:	:	PUNCT
easat-4310	30	16	2576	2576	NUM
easat-4310	30	17	-	-	SYM
easat-4310	30	18	8484	8484	NUM
easat-4310	30	19	vol	vol	NOUN
easat-4310	30	20	.	.	PROPN
easat-4310	31	1	9	9	NUM
easat-4310	31	2	,	,	PUNCT
easat-4310	31	3	no	no	INTJ
easat-4310	31	4	.	.	NOUN
easat-4310	31	5	1	1	NUM
easat-4310	31	6	:	:	SYM
easat-4310	31	7	1078	1078	NUM
easat-4310	31	8	-	-	SYM
easat-4310	31	9	1085	1085	NUM
easat-4310	31	10	,	,	PUNCT
easat-4310	31	11	2025	2025	NUM
easat-4310	31	12	doi	doi	NOUN
easat-4310	31	13	:	:	PUNCT
easat-4310	31	14	10.55214/25768484.v9i1.4310	10.55214/25768484.v9i1.4310	NUM
easat-4310	31	15	©	©	PROPN
easat-4310	31	16	2025	2025	NUM
easat-4310	31	17	by	by	ADP
easat-4310	31	18	the	the	DET
easat-4310	31	19	authors	author	NOUN
easat-4310	31	20	;	;	PUNCT
easat-4310	31	21	licensee	licensee	PROPN
easat-4310	31	22	learning	learning	NOUN
easat-4310	31	23	gate	gate	VERB
easat-4310	31	24	potentially	potentially	ADV
easat-4310	31	25	impacting	impact	VERB
easat-4310	31	26	overall	overall	ADJ
easat-4310	31	27	survival	survival	NOUN
easat-4310	31	28	outcomes	outcome	NOUN
easat-4310	31	29	.	.	PUNCT
easat-4310	32	1	gi	gi	VERB
easat-4310	32	2	mucositis	mucositis	PROPN
easat-4310	32	3	leads	lead	VERB
easat-4310	32	4	to	to	ADP
easat-4310	32	5	mucosal	mucosal	ADJ
easat-4310	32	6	damage	damage	NOUN
easat-4310	32	7	,	,	PUNCT
easat-4310	32	8	impaired	impaired	ADJ
easat-4310	32	9	nutrient	nutrient	NOUN
easat-4310	32	10	absorption	absorption	NOUN
easat-4310	32	11	,	,	PUNCT
easat-4310	32	12	and	and	CCONJ
easat-4310	32	13	increased	increase	VERB
easat-4310	32	14	susceptibility	susceptibility	NOUN
easat-4310	32	15	to	to	ADP
easat-4310	32	16	systemic	systemic	ADJ
easat-4310	32	17	infections	infection	NOUN
easat-4310	32	18	,	,	PUNCT
easat-4310	32	19	thereby	thereby	ADV
easat-4310	32	20	impacting	impact	VERB
easat-4310	32	21	both	both	DET
easat-4310	32	22	quality	quality	NOUN
easat-4310	32	23	of	of	ADP
easat-4310	32	24	life	life	NOUN
easat-4310	32	25	and	and	CCONJ
easat-4310	32	26	treatment	treatment	NOUN
easat-4310	32	27	continuity	continuity	NOUN
easat-4310	32	28	,	,	PUNCT
easat-4310	32	29	which	which	PRON
easat-4310	32	30	are	be	AUX
easat-4310	32	31	critical	critical	ADJ
easat-4310	32	32	for	for	ADP
easat-4310	32	33	achieving	achieve	VERB
easat-4310	32	34	optimal	optimal	ADJ
easat-4310	32	35	survival	survival	NOUN
easat-4310	32	36	outcomes	outcome	NOUN
easat-4310	32	37	[	[	X
easat-4310	32	38	4	4	NUM
easat-4310	32	39	]	]	PUNCT
easat-4310	32	40	.	.	PUNCT
easat-4310	33	1	while	while	SCONJ
easat-4310	33	2	diagnostic	diagnostic	ADJ
easat-4310	33	3	methods	method	NOUN
easat-4310	33	4	like	like	ADP
easat-4310	33	5	intestinal	intestinal	ADJ
easat-4310	33	6	biopsies	biopsy	NOUN
easat-4310	33	7	remain	remain	VERB
easat-4310	33	8	invasive	invasive	ADJ
easat-4310	33	9	and	and	CCONJ
easat-4310	33	10	impractical	impractical	ADJ
easat-4310	33	11	for	for	ADP
easat-4310	33	12	routine	routine	ADJ
easat-4310	33	13	use	use	NOUN
easat-4310	33	14	in	in	ADP
easat-4310	33	15	pediatric	pediatric	ADJ
easat-4310	33	16	patients	patient	NOUN
easat-4310	33	17	,	,	PUNCT
easat-4310	33	18	this	this	PRON
easat-4310	33	19	underscores	underscore	VERB
easat-4310	33	20	the	the	DET
easat-4310	33	21	urgent	urgent	ADJ
easat-4310	33	22	need	need	NOUN
easat-4310	33	23	for	for	SCONJ
easat-4310	33	24	non	non	ADJ
easat-4310	33	25	-	-	ADJ
easat-4310	33	26	invasive	invasive	ADJ
easat-4310	33	27	biomarkers	biomarker	NOUN
easat-4310	33	28	to	to	PART
easat-4310	33	29	evaluate	evaluate	VERB
easat-4310	33	30	intestinal	intestinal	ADJ
easat-4310	33	31	integrity	integrity	NOUN
easat-4310	33	32	and	and	CCONJ
easat-4310	33	33	predict	predict	VERB
easat-4310	33	34	mucosal	mucosal	ADJ
easat-4310	33	35	damage	damage	NOUN
easat-4310	33	36	[	[	X
easat-4310	33	37	5	5	NUM
easat-4310	33	38	]	]	PUNCT
easat-4310	33	39	.	.	PUNCT
easat-4310	34	1	current	current	ADJ
easat-4310	34	2	diagnostic	diagnostic	ADJ
easat-4310	34	3	methods	method	NOUN
easat-4310	34	4	for	for	ADP
easat-4310	34	5	gi	gi	NUM
easat-4310	34	6	mucositis	mucositis	PROPN
easat-4310	34	7	,	,	PUNCT
easat-4310	34	8	including	include	VERB
easat-4310	34	9	intestinal	intestinal	ADJ
easat-4310	34	10	biopsy	biopsy	NOUN
easat-4310	34	11	,	,	PUNCT
easat-4310	34	12	are	be	AUX
easat-4310	34	13	invasive	invasive	ADJ
easat-4310	34	14	and	and	CCONJ
easat-4310	34	15	impractical	impractical	ADJ
easat-4310	34	16	for	for	ADP
easat-4310	34	17	routine	routine	ADJ
easat-4310	34	18	use	use	NOUN
easat-4310	34	19	in	in	ADP
easat-4310	34	20	pediatric	pediatric	ADJ
easat-4310	34	21	populations	population	NOUN
easat-4310	34	22	.	.	PUNCT
easat-4310	35	1	this	this	DET
easat-4310	35	2	limitation	limitation	NOUN
easat-4310	35	3	underscores	underscore	VERB
easat-4310	35	4	the	the	DET
easat-4310	35	5	need	need	NOUN
easat-4310	35	6	for	for	ADP
easat-4310	35	7	non	non	ADJ
easat-4310	35	8	-	-	ADJ
easat-4310	35	9	invasive	invasive	ADJ
easat-4310	35	10	biomarkers	biomarker	NOUN
easat-4310	35	11	that	that	PRON
easat-4310	35	12	can	can	AUX
easat-4310	35	13	reliably	reliably	ADV
easat-4310	35	14	assess	assess	VERB
easat-4310	35	15	intestinal	intestinal	ADJ
easat-4310	35	16	integrity	integrity	NOUN
easat-4310	35	17	and	and	CCONJ
easat-4310	35	18	predict	predict	VERB
easat-4310	35	19	mucosal	mucosal	ADJ
easat-4310	35	20	damage	damage	NOUN
easat-4310	35	21	.	.	PUNCT
easat-4310	36	1	citrulline	citrulline	NOUN
easat-4310	36	2	,	,	PUNCT
easat-4310	36	3	a	a	DET
easat-4310	36	4	non	non	ADJ
easat-4310	36	5	-	-	ADJ
easat-4310	36	6	protein	protein	ADJ
easat-4310	36	7	amino	amino	NOUN
easat-4310	36	8	acid	acid	NOUN
easat-4310	36	9	primarily	primarily	ADV
easat-4310	36	10	synthesized	synthesize	VERB
easat-4310	36	11	by	by	ADP
easat-4310	36	12	enterocytes	enterocyte	NOUN
easat-4310	36	13	,	,	PUNCT
easat-4310	36	14	has	have	AUX
easat-4310	36	15	emerged	emerge	VERB
easat-4310	36	16	as	as	ADP
easat-4310	36	17	a	a	DET
easat-4310	36	18	promising	promising	ADJ
easat-4310	36	19	candidate	candidate	NOUN
easat-4310	36	20	.	.	PUNCT
easat-4310	37	1	serum	serum	PROPN
easat-4310	37	2	citrulline	citrulline	NOUN
easat-4310	37	3	levels	level	NOUN
easat-4310	37	4	are	be	AUX
easat-4310	37	5	directly	directly	ADV
easat-4310	37	6	proportional	proportional	ADJ
easat-4310	37	7	to	to	ADP
easat-4310	37	8	functional	functional	ADJ
easat-4310	37	9	enterocyte	enterocyte	NOUN
easat-4310	37	10	mass	mass	PROPN
easat-4310	37	11	,	,	PUNCT
easat-4310	37	12	making	make	VERB
easat-4310	37	13	it	it	PRON
easat-4310	37	14	a	a	DET
easat-4310	37	15	sensitive	sensitive	ADJ
easat-4310	37	16	and	and	CCONJ
easat-4310	37	17	specific	specific	ADJ
easat-4310	37	18	marker	marker	NOUN
easat-4310	37	19	of	of	ADP
easat-4310	37	20	intestinal	intestinal	ADJ
easat-4310	37	21	mucosal	mucosal	NOUN
easat-4310	37	22	health	health	NOUN
easat-4310	38	1	[	[	X
easat-4310	38	2	6	6	NUM
easat-4310	38	3	]	]	PUNCT
easat-4310	38	4	.	.	PUNCT
easat-4310	39	1	a	a	DET
easat-4310	39	2	decline	decline	NOUN
easat-4310	39	3	in	in	ADP
easat-4310	39	4	citrulline	citrulline	NOUN
easat-4310	39	5	levels	level	NOUN
easat-4310	39	6	is	be	AUX
easat-4310	39	7	strongly	strongly	ADV
easat-4310	39	8	associated	associate	VERB
easat-4310	39	9	with	with	ADP
easat-4310	39	10	mucosal	mucosal	NOUN
easat-4310	39	11	injury	injury	NOUN
easat-4310	39	12	,	,	PUNCT
easat-4310	39	13	as	as	SCONJ
easat-4310	39	14	demonstrated	demonstrate	VERB
easat-4310	39	15	in	in	ADP
easat-4310	39	16	various	various	ADJ
easat-4310	39	17	clinical	clinical	ADJ
easat-4310	39	18	and	and	CCONJ
easat-4310	39	19	preclinical	preclinical	ADJ
easat-4310	39	20	studies	study	NOUN
easat-4310	39	21	[	[	X
easat-4310	39	22	7	7	NUM
easat-4310	39	23	]	]	PUNCT
easat-4310	39	24	.	.	PUNCT
easat-4310	40	1	despite	despite	SCONJ
easat-4310	40	2	its	its	PRON
easat-4310	40	3	potential	potential	NOUN
easat-4310	40	4	,	,	PUNCT
easat-4310	40	5	the	the	DET
easat-4310	40	6	application	application	NOUN
easat-4310	40	7	of	of	ADP
easat-4310	40	8	citrulline	citrulline	NOUN
easat-4310	40	9	as	as	ADP
easat-4310	40	10	a	a	DET
easat-4310	40	11	biomarker	biomarker	NOUN
easat-4310	40	12	in	in	ADP
easat-4310	40	13	pediatric	pediatric	ADJ
easat-4310	40	14	oncology	oncology	NOUN
easat-4310	40	15	,	,	PUNCT
easat-4310	40	16	particularly	particularly	ADV
easat-4310	40	17	in	in	ADP
easat-4310	40	18	the	the	DET
easat-4310	40	19	context	context	NOUN
easat-4310	40	20	of	of	ADP
easat-4310	40	21	hd	hd	NOUN
easat-4310	40	22	-	-	PUNCT
easat-4310	40	23	mtx	mtx	NOUN
easat-4310	40	24	-	-	ADJ
easat-4310	40	25	induced	induced	ADJ
easat-4310	40	26	mucositis	mucositis	NOUN
easat-4310	40	27	,	,	PUNCT
easat-4310	40	28	remains	remain	VERB
easat-4310	40	29	underexplored	underexplored	ADJ
easat-4310	40	30	.	.	PUNCT
easat-4310	41	1	most	most	ADJ
easat-4310	41	2	existing	exist	VERB
easat-4310	41	3	studies	study	NOUN
easat-4310	41	4	have	have	AUX
easat-4310	41	5	focused	focus	VERB
easat-4310	41	6	on	on	ADP
easat-4310	41	7	adult	adult	NOUN
easat-4310	41	8	populations	population	NOUN
easat-4310	41	9	or	or	CCONJ
easat-4310	41	10	other	other	ADJ
easat-4310	41	11	chemotherapeutic	chemotherapeutic	ADJ
easat-4310	41	12	agents	agent	NOUN
easat-4310	41	13	,	,	PUNCT
easat-4310	41	14	leaving	leave	VERB
easat-4310	41	15	a	a	DET
easat-4310	41	16	significant	significant	ADJ
easat-4310	41	17	gap	gap	NOUN
easat-4310	41	18	in	in	ADP
easat-4310	41	19	understanding	understand	VERB
easat-4310	41	20	its	its	PRON
easat-4310	41	21	utility	utility	NOUN
easat-4310	41	22	in	in	ADP
easat-4310	41	23	children	child	NOUN
easat-4310	41	24	undergoing	undergo	VERB
easat-4310	41	25	all	all	DET
easat-4310	41	26	treatment	treatment	NOUN
easat-4310	41	27	[	[	X
easat-4310	41	28	8	8	NUM
easat-4310	41	29	]	]	PUNCT
easat-4310	41	30	.	.	PUNCT
easat-4310	42	1	furthermore	furthermore	ADV
easat-4310	42	2	,	,	PUNCT
easat-4310	42	3	differences	difference	NOUN
easat-4310	42	4	in	in	ADP
easat-4310	42	5	physiological	physiological	ADJ
easat-4310	42	6	responses	response	NOUN
easat-4310	42	7	between	between	ADP
easat-4310	42	8	risk	risk	NOUN
easat-4310	42	9	groups	group	NOUN
easat-4310	42	10	,	,	PUNCT
easat-4310	42	11	such	such	ADJ
easat-4310	42	12	as	as	ADP
easat-4310	42	13	standard	standard	ADJ
easat-4310	42	14	risk	risk	NOUN
easat-4310	42	15	(	(	PUNCT
easat-4310	42	16	sr	sr	PROPN
easat-4310	42	17	)	)	PUNCT
easat-4310	42	18	and	and	CCONJ
easat-4310	42	19	high	high	ADJ
easat-4310	42	20	risk	risk	NOUN
easat-4310	42	21	(	(	PUNCT
easat-4310	42	22	hr	hr	NOUN
easat-4310	42	23	)	)	PUNCT
easat-4310	42	24	,	,	PUNCT
easat-4310	42	25	may	may	AUX
easat-4310	42	26	influence	influence	VERB
easat-4310	42	27	citrulline	citrulline	NOUN
easat-4310	42	28	dynamics	dynamic	NOUN
easat-4310	42	29	and	and	CCONJ
easat-4310	42	30	warrant	warrant	VERB
easat-4310	42	31	detailed	detailed	ADJ
easat-4310	42	32	investigation	investigation	NOUN
easat-4310	42	33	[	[	X
easat-4310	42	34	9	9	NUM
easat-4310	42	35	]	]	PUNCT
easat-4310	42	36	.	.	PUNCT
easat-4310	43	1	this	this	DET
easat-4310	43	2	study	study	NOUN
easat-4310	43	3	aims	aim	VERB
easat-4310	43	4	to	to	PART
easat-4310	43	5	evaluate	evaluate	VERB
easat-4310	43	6	the	the	DET
easat-4310	43	7	changes	change	NOUN
easat-4310	43	8	in	in	ADP
easat-4310	43	9	citrulline	citrulline	NOUN
easat-4310	43	10	levels	level	NOUN
easat-4310	43	11	before	before	ADP
easat-4310	43	12	and	and	CCONJ
easat-4310	43	13	after	after	ADP
easat-4310	43	14	hd	hd	NOUN
easat-4310	43	15	-	-	PUNCT
easat-4310	43	16	mtx	mtx	NOUN
easat-4310	43	17	chemotherapy	chemotherapy	NOUN
easat-4310	43	18	in	in	ADP
easat-4310	43	19	children	child	NOUN
easat-4310	43	20	with	with	ADP
easat-4310	43	21	all	all	PRON
easat-4310	43	22	during	during	ADP
easat-4310	43	23	the	the	DET
easat-4310	43	24	consolidation	consolidation	NOUN
easat-4310	43	25	phase	phase	NOUN
easat-4310	43	26	.	.	PUNCT
easat-4310	44	1	specifically	specifically	ADV
easat-4310	44	2	,	,	PUNCT
easat-4310	44	3	it	it	PRON
easat-4310	44	4	seeks	seek	VERB
easat-4310	44	5	to	to	PART
easat-4310	44	6	determine	determine	VERB
easat-4310	44	7	whether	whether	SCONJ
easat-4310	44	8	citrulline	citrulline	NOUN
easat-4310	44	9	can	can	AUX
easat-4310	44	10	serve	serve	VERB
easat-4310	44	11	as	as	ADP
easat-4310	44	12	a	a	DET
easat-4310	44	13	reliable	reliable	ADJ
easat-4310	44	14	biomarker	biomarker	NOUN
easat-4310	44	15	for	for	ADP
easat-4310	44	16	detecting	detect	VERB
easat-4310	44	17	and	and	CCONJ
easat-4310	44	18	monitoring	monitor	VERB
easat-4310	44	19	gi	gi	ADP
easat-4310	44	20	mucositis	mucositis	PROPN
easat-4310	44	21	.	.	PUNCT
easat-4310	45	1	by	by	ADP
easat-4310	45	2	addressing	address	VERB
easat-4310	45	3	these	these	DET
easat-4310	45	4	objectives	objective	NOUN
easat-4310	45	5	,	,	PUNCT
easat-4310	45	6	the	the	DET
easat-4310	45	7	study	study	NOUN
easat-4310	45	8	aims	aim	VERB
easat-4310	45	9	to	to	PART
easat-4310	45	10	provide	provide	VERB
easat-4310	45	11	critical	critical	ADJ
easat-4310	45	12	insights	insight	NOUN
easat-4310	45	13	into	into	ADP
easat-4310	45	14	the	the	DET
easat-4310	45	15	utility	utility	NOUN
easat-4310	45	16	of	of	ADP
easat-4310	45	17	citrulline	citrulline	NOUN
easat-4310	45	18	in	in	ADP
easat-4310	45	19	clinical	clinical	ADJ
easat-4310	45	20	practice	practice	NOUN
easat-4310	45	21	,	,	PUNCT
easat-4310	45	22	potentially	potentially	ADV
easat-4310	45	23	paving	pave	VERB
easat-4310	45	24	the	the	DET
easat-4310	45	25	way	way	NOUN
easat-4310	45	26	for	for	ADP
easat-4310	45	27	more	more	ADV
easat-4310	45	28	personalized	personalized	ADJ
easat-4310	45	29	and	and	CCONJ
easat-4310	45	30	less	less	ADV
easat-4310	45	31	invasive	invasive	ADJ
easat-4310	45	32	approaches	approach	NOUN
easat-4310	45	33	to	to	ADP
easat-4310	45	34	managing	manage	VERB
easat-4310	45	35	chemotherapy	chemotherapy	NOUN
easat-4310	45	36	-	-	PUNCT
easat-4310	45	37	related	relate	VERB
easat-4310	45	38	complications	complication	NOUN
easat-4310	45	39	in	in	ADP
easat-4310	45	40	pediatric	pediatric	ADJ
easat-4310	45	41	oncology	oncology	NOUN
easat-4310	45	42	[	[	X
easat-4310	45	43	10	10	NUM
easat-4310	45	44	]	]	PUNCT
easat-4310	45	45	.	.	PUNCT
easat-4310	46	1	2	2	X
easat-4310	46	2	.	.	X
easat-4310	46	3	material	material	NOUN
easat-4310	46	4	and	and	CCONJ
easat-4310	46	5	methods	method	NOUN
easat-4310	46	6	a	a	DET
easat-4310	46	7	cross	cross	ADJ
easat-4310	46	8	-	-	ADJ
easat-4310	46	9	sectional	sectional	ADJ
easat-4310	46	10	design	design	NOUN
easat-4310	46	11	was	be	AUX
easat-4310	46	12	utilized	utilize	VERB
easat-4310	46	13	to	to	PART
easat-4310	46	14	evaluate	evaluate	VERB
easat-4310	46	15	the	the	DET
easat-4310	46	16	relationship	relationship	NOUN
easat-4310	46	17	between	between	ADP
easat-4310	46	18	citrulline	citrulline	NOUN
easat-4310	46	19	levels	level	NOUN
easat-4310	46	20	and	and	CCONJ
easat-4310	46	21	gastrointestinal	gastrointestinal	ADJ
easat-4310	46	22	(	(	PUNCT
easat-4310	46	23	gi	gi	INTJ
easat-4310	46	24	)	)	PUNCT
easat-4310	46	25	mucositis	mucositis	NOUN
easat-4310	46	26	in	in	ADP
easat-4310	46	27	pediatric	pediatric	ADJ
easat-4310	46	28	34	34	NUM
easat-4310	46	29	patients	patient	NOUN
easat-4310	46	30	diagnosed	diagnose	VERB
easat-4310	46	31	with	with	ADP
easat-4310	46	32	acute	acute	ADJ
easat-4310	46	33	lymphoblastic	lymphoblastic	ADJ
easat-4310	46	34	leukemia	leukemia	NOUN
easat-4310	46	35	(	(	PUNCT
easat-4310	46	36	all	all	ADV
easat-4310	46	37	)	)	PUNCT
easat-4310	46	38	during	during	ADP
easat-4310	46	39	the	the	DET
easat-4310	46	40	consolidation	consolidation	NOUN
easat-4310	46	41	phase	phase	NOUN
easat-4310	46	42	of	of	ADP
easat-4310	46	43	their	their	PRON
easat-4310	46	44	treatment	treatment	NOUN
easat-4310	46	45	.	.	PUNCT
easat-4310	47	1	the	the	DET
easat-4310	47	2	study	study	NOUN
easat-4310	47	3	was	be	AUX
easat-4310	47	4	conducted	conduct	VERB
easat-4310	47	5	at	at	ADP
easat-4310	47	6	a	a	DET
easat-4310	47	7	tertiary	tertiary	ADJ
easat-4310	47	8	care	care	NOUN
easat-4310	47	9	hospital	hospital	NOUN
easat-4310	47	10	specializing	specialize	VERB
easat-4310	47	11	in	in	ADP
easat-4310	47	12	pediatric	pediatric	ADJ
easat-4310	47	13	oncology	oncology	NOUN
easat-4310	47	14	.	.	PUNCT
easat-4310	48	1	ethical	ethical	ADJ
easat-4310	48	2	approval	approval	NOUN
easat-4310	48	3	was	be	AUX
easat-4310	48	4	obtained	obtain	VERB
easat-4310	48	5	from	from	ADP
easat-4310	48	6	the	the	DET
easat-4310	48	7	institutional	institutional	ADJ
easat-4310	48	8	review	review	NOUN
easat-4310	48	9	board	board	NOUN
easat-4310	48	10	,	,	PUNCT
easat-4310	48	11	and	and	CCONJ
easat-4310	48	12	written	write	VERB
easat-4310	48	13	informed	informed	ADJ
easat-4310	48	14	consent	consent	NOUN
easat-4310	48	15	was	be	AUX
easat-4310	48	16	secured	secure	VERB
easat-4310	48	17	from	from	ADP
easat-4310	48	18	all	all	DET
easat-4310	48	19	participants	participant	NOUN
easat-4310	48	20	or	or	CCONJ
easat-4310	48	21	their	their	PRON
easat-4310	48	22	legal	legal	ADJ
easat-4310	48	23	guardians	guardian	NOUN
easat-4310	48	24	.	.	PUNCT
easat-4310	49	1	the	the	DET
easat-4310	49	2	study	study	NOUN
easat-4310	49	3	population	population	NOUN
easat-4310	49	4	consisted	consist	VERB
easat-4310	49	5	of	of	ADP
easat-4310	49	6	pediatric	pediatric	ADJ
easat-4310	49	7	patients	patient	NOUN
easat-4310	49	8	diagnosed	diagnose	VERB
easat-4310	49	9	with	with	ADP
easat-4310	49	10	all	all	PRON
easat-4310	49	11	undergoing	undergo	VERB
easat-4310	49	12	high	high	ADJ
easat-4310	49	13	-	-	PUNCT
easat-4310	49	14	dose	dose	NOUN
easat-4310	49	15	methotrexate	methotrexate	NOUN
easat-4310	49	16	(	(	PUNCT
easat-4310	49	17	hd	hd	NOUN
easat-4310	49	18	-	-	PUNCT
easat-4310	49	19	mtx	mtx	NOUN
easat-4310	49	20	)	)	PUNCT
easat-4310	49	21	chemotherapy	chemotherapy	NOUN
easat-4310	49	22	.	.	PUNCT
easat-4310	50	1	inclusion	inclusion	NOUN
easat-4310	50	2	criteria	criterion	NOUN
easat-4310	50	3	required	require	VERB
easat-4310	50	4	patients	patient	NOUN
easat-4310	50	5	to	to	PART
easat-4310	50	6	have	have	VERB
easat-4310	50	7	a	a	DET
easat-4310	50	8	confirmed	confirm	VERB
easat-4310	50	9	diagnosis	diagnosis	NOUN
easat-4310	50	10	of	of	ADP
easat-4310	50	11	all	all	PRON
easat-4310	50	12	,	,	PUNCT
easat-4310	50	13	eligibility	eligibility	NOUN
easat-4310	50	14	for	for	ADP
easat-4310	50	15	hd	hd	NOUN
easat-4310	50	16	-	-	NOUN
easat-4310	50	17	mtx	mtx	NOUN
easat-4310	50	18	during	during	ADP
easat-4310	50	19	the	the	DET
easat-4310	50	20	consolidation	consolidation	NOUN
easat-4310	50	21	phase	phase	NOUN
easat-4310	50	22	,	,	PUNCT
easat-4310	50	23	and	and	CCONJ
easat-4310	50	24	the	the	DET
easat-4310	50	25	absence	absence	NOUN
easat-4310	50	26	of	of	ADP
easat-4310	50	27	preexisting	preexist	VERB
easat-4310	50	28	gastrointestinal	gastrointestinal	ADJ
easat-4310	50	29	disorders	disorder	NOUN
easat-4310	50	30	.	.	PUNCT
easat-4310	51	1	patients	patient	NOUN
easat-4310	51	2	with	with	ADP
easat-4310	51	3	incomplete	incomplete	ADJ
easat-4310	51	4	data	datum	NOUN
easat-4310	51	5	,	,	PUNCT
easat-4310	51	6	a	a	DET
easat-4310	51	7	history	history	NOUN
easat-4310	51	8	of	of	ADP
easat-4310	51	9	malabsorption	malabsorption	NOUN
easat-4310	51	10	syndromes	syndrome	NOUN
easat-4310	51	11	,	,	PUNCT
easat-4310	51	12	renal	renal	ADJ
easat-4310	51	13	failure	failure	NOUN
easat-4310	51	14	or	or	CCONJ
easat-4310	51	15	other	other	ADJ
easat-4310	51	16	concurrent	concurrent	ADJ
easat-4310	51	17	conditions	condition	NOUN
easat-4310	51	18	affecting	affect	VERB
easat-4310	51	19	citrulline	citrulline	NOUN
easat-4310	51	20	metabolism	metabolism	NOUN
easat-4310	51	21	were	be	AUX
easat-4310	51	22	excluded	exclude	VERB
easat-4310	51	23	from	from	ADP
easat-4310	51	24	the	the	DET
easat-4310	51	25	study	study	NOUN
easat-4310	51	26	.	.	PUNCT
easat-4310	52	1	demographic	demographic	ADJ
easat-4310	52	2	and	and	CCONJ
easat-4310	52	3	clinical	clinical	ADJ
easat-4310	52	4	data	datum	NOUN
easat-4310	52	5	,	,	PUNCT
easat-4310	52	6	including	include	VERB
easat-4310	52	7	age	age	NOUN
easat-4310	52	8	,	,	PUNCT
easat-4310	52	9	sex	sex	NOUN
easat-4310	52	10	,	,	PUNCT
easat-4310	52	11	nutritional	nutritional	ADJ
easat-4310	52	12	status	status	NOUN
easat-4310	52	13	,	,	PUNCT
easat-4310	52	14	and	and	CCONJ
easat-4310	52	15	risk	risk	NOUN
easat-4310	52	16	stratification	stratification	NOUN
easat-4310	52	17	(	(	PUNCT
easat-4310	52	18	standard	standard	ADJ
easat-4310	52	19	risk	risk	NOUN
easat-4310	53	1	[	[	X
easat-4310	53	2	sr	sr	X
easat-4310	53	3	]	]	PUNCT
easat-4310	53	4	and	and	CCONJ
easat-4310	53	5	high	high	ADJ
easat-4310	53	6	risk	risk	NOUN
easat-4310	54	1	[	[	X
easat-4310	54	2	hr	hr	X
easat-4310	54	3	]	]	X
easat-4310	54	4	)	)	PUNCT
easat-4310	54	5	,	,	PUNCT
easat-4310	54	6	were	be	AUX
easat-4310	54	7	recorded	record	VERB
easat-4310	54	8	.	.	PUNCT
easat-4310	55	1	nutritional	nutritional	ADJ
easat-4310	55	2	status	status	NOUN
easat-4310	55	3	was	be	AUX
easat-4310	55	4	classified	classify	VERB
easat-4310	55	5	as	as	ADP
easat-4310	55	6	normal	normal	ADJ
easat-4310	55	7	,	,	PUNCT
easat-4310	55	8	undernourished	undernourished	ADJ
easat-4310	55	9	,	,	PUNCT
easat-4310	55	10	overnourished	overnourishe	VERB
easat-4310	55	11	,	,	PUNCT
easat-4310	55	12	or	or	CCONJ
easat-4310	55	13	obese	obese	NOUN
easat-4310	55	14	based	base	VERB
easat-4310	55	15	on	on	ADP
easat-4310	55	16	standardized	standardized	ADJ
easat-4310	55	17	pediatric	pediatric	ADJ
easat-4310	55	18	growth	growth	NOUN
easat-4310	55	19	charts	chart	NOUN
easat-4310	55	20	.	.	PUNCT
easat-4310	56	1	serum	serum	PROPN
easat-4310	56	2	citrulline	citrulline	NOUN
easat-4310	56	3	levels	level	NOUN
easat-4310	56	4	were	be	AUX
easat-4310	56	5	measured	measure	VERB
easat-4310	56	6	at	at	ADP
easat-4310	56	7	two	two	NUM
easat-4310	56	8	time	time	NOUN
easat-4310	56	9	points	point	NOUN
easat-4310	56	10	:	:	PUNCT
easat-4310	56	11	prior	prior	ADV
easat-4310	56	12	to	to	ADP
easat-4310	56	13	hd	hd	NOUN
easat-4310	56	14	-	-	PUNCT
easat-4310	56	15	mtx	mtx	NOUN
easat-4310	56	16	administration	administration	NOUN
easat-4310	56	17	(	(	PUNCT
easat-4310	56	18	baseline	baseline	PROPN
easat-4310	56	19	)	)	PUNCT
easat-4310	56	20	and	and	CCONJ
easat-4310	56	21	48	48	NUM
easat-4310	56	22	hours	hour	NOUN
easat-4310	56	23	after	after	ADP
easat-4310	56	24	chemotherapy	chemotherapy	NOUN
easat-4310	56	25	.	.	PUNCT
easat-4310	57	1	blood	blood	NOUN
easat-4310	57	2	samples	sample	NOUN
easat-4310	57	3	were	be	AUX
easat-4310	57	4	collected	collect	VERB
easat-4310	57	5	via	via	ADP
easat-4310	57	6	venipuncture	venipuncture	NOUN
easat-4310	57	7	and	and	CCONJ
easat-4310	57	8	processed	process	VERB
easat-4310	57	9	immediately	immediately	ADV
easat-4310	57	10	to	to	PART
easat-4310	57	11	ensure	ensure	VERB
easat-4310	57	12	accuracy	accuracy	NOUN
easat-4310	57	13	from	from	ADP
easat-4310	57	14	routine	routine	ADJ
easat-4310	57	15	check	check	NOUN
easat-4310	57	16	.	.	PUNCT
easat-4310	58	1	citrulline	citrulline	NOUN
easat-4310	58	2	concentrations	concentration	NOUN
easat-4310	58	3	were	be	AUX
easat-4310	58	4	analyzed	analyze	VERB
easat-4310	58	5	using	use	VERB
easat-4310	58	6	high	high	ADJ
easat-4310	58	7	-	-	PUNCT
easat-4310	58	8	performance	performance	NOUN
easat-4310	58	9	liquid	liquid	ADJ
easat-4310	58	10	chromatography	chromatography	NOUN
easat-4310	58	11	(	(	PUNCT
easat-4310	58	12	hplc	hplc	PROPN
easat-4310	58	13	)	)	PUNCT
easat-4310	58	14	,	,	PUNCT
easat-4310	58	15	a	a	DET
easat-4310	58	16	method	method	NOUN
easat-4310	58	17	validated	validate	VERB
easat-4310	58	18	for	for	ADP
easat-4310	58	19	precision	precision	NOUN
easat-4310	58	20	and	and	CCONJ
easat-4310	58	21	reliability	reliability	NOUN
easat-4310	58	22	in	in	ADP
easat-4310	58	23	clinical	clinical	ADJ
easat-4310	58	24	settings	setting	NOUN
easat-4310	58	25	[	[	X
easat-4310	58	26	11	11	NUM
easat-4310	58	27	]	]	PUNCT
easat-4310	58	28	.	.	PUNCT
easat-4310	59	1	gi	gi	AUX
easat-4310	59	2	mucositis	mucositis	PROPN
easat-4310	59	3	severity	severity	NOUN
easat-4310	59	4	was	be	AUX
easat-4310	59	5	assessed	assess	VERB
easat-4310	59	6	using	use	VERB
easat-4310	59	7	the	the	DET
easat-4310	59	8	national	national	PROPN
easat-4310	59	9	cancer	cancer	PROPN
easat-4310	59	10	institute	institute	PROPN
easat-4310	59	11	(	(	PUNCT
easat-4310	59	12	nci	nci	PROPN
easat-4310	59	13	)	)	PUNCT
easat-4310	59	14	common	common	ADJ
easat-4310	59	15	terminology	terminology	NOUN
easat-4310	59	16	criteria	criterion	NOUN
easat-4310	59	17	for	for	ADP
easat-4310	59	18	adverse	adverse	ADJ
easat-4310	59	19	events	event	NOUN
easat-4310	59	20	.	.	PUNCT
easat-4310	60	1	mucositis	mucositis	PROPN
easat-4310	60	2	was	be	AUX
easat-4310	60	3	graded	grade	VERB
easat-4310	60	4	on	on	ADP
easat-4310	60	5	a	a	DET
easat-4310	60	6	scale	scale	NOUN
easat-4310	60	7	from	from	ADP
easat-4310	60	8	0	0	NUM
easat-4310	60	9	(	(	PUNCT
easat-4310	60	10	no	no	DET
easat-4310	60	11	mucositis	mucositis	NOUN
easat-4310	60	12	)	)	PUNCT
easat-4310	60	13	to	to	ADP
easat-4310	60	14	4	4	NUM
easat-4310	60	15	(	(	PUNCT
easat-4310	60	16	life	life	NOUN
easat-4310	60	17	-	-	PUNCT
easat-4310	60	18	threatening	threaten	VERB
easat-4310	60	19	mucositis	mucositis	NOUN
easat-4310	60	20	)	)	PUNCT
easat-4310	60	21	,	,	PUNCT
easat-4310	60	22	with	with	ADP
easat-4310	60	23	particular	particular	ADJ
easat-4310	60	24	attention	attention	NOUN
easat-4310	60	25	to	to	ADP
easat-4310	60	26	grades	grade	NOUN
easat-4310	60	27	1	1	NUM
easat-4310	60	28	and	and	CCONJ
easat-4310	60	29	2	2	NUM
easat-4310	60	30	,	,	PUNCT
easat-4310	60	31	which	which	PRON
easat-4310	60	32	were	be	AUX
easat-4310	60	33	most	most	ADV
easat-4310	60	34	prevalent	prevalent	ADJ
easat-4310	60	35	in	in	ADP
easat-4310	60	36	this	this	DET
easat-4310	60	37	study	study	NOUN
easat-4310	60	38	population	population	NOUN
easat-4310	61	1	[	[	X
easat-4310	61	2	12	12	NUM
easat-4310	61	3	]	]	PUNCT
easat-4310	61	4	.	.	PUNCT
easat-4310	62	1	data	datum	NOUN
easat-4310	62	2	analysis	analysis	NOUN
easat-4310	62	3	was	be	AUX
easat-4310	62	4	conducted	conduct	VERB
easat-4310	62	5	using	use	VERB
easat-4310	62	6	spss	spss	PROPN
easat-4310	62	7	version	version	NOUN
easat-4310	62	8	25	25	NUM
easat-4310	62	9	.	.	PUNCT
easat-4310	63	1	descriptive	descriptive	ADJ
easat-4310	63	2	statistics	statistic	NOUN
easat-4310	63	3	were	be	AUX
easat-4310	63	4	used	use	VERB
easat-4310	63	5	to	to	PART
easat-4310	63	6	summarize	summarize	VERB
easat-4310	63	7	demographic	demographic	ADJ
easat-4310	63	8	and	and	CCONJ
easat-4310	63	9	clinical	clinical	ADJ
easat-4310	63	10	characteristics	characteristic	NOUN
easat-4310	63	11	.	.	PUNCT
easat-4310	64	1	continuous	continuous	ADJ
easat-4310	64	2	variables	variable	NOUN
easat-4310	64	3	,	,	PUNCT
easat-4310	64	4	including	include	VERB
easat-4310	64	5	citrulline	citrulline	NOUN
easat-4310	64	6	levels	level	NOUN
easat-4310	64	7	,	,	PUNCT
easat-4310	64	8	were	be	AUX
easat-4310	64	9	expressed	express	VERB
easat-4310	64	10	as	as	ADP
easat-4310	64	11	means	mean	NOUN
easat-4310	64	12	and	and	CCONJ
easat-4310	64	13	standard	standard	ADJ
easat-4310	64	14	deviations	deviation	NOUN
easat-4310	64	15	or	or	CCONJ
easat-4310	64	16	medians	median	NOUN
easat-4310	64	17	and	and	CCONJ
easat-4310	64	18	interquartile	interquartile	NOUN
easat-4310	64	19	ranges	range	NOUN
easat-4310	64	20	,	,	PUNCT
easat-4310	64	21	depending	depend	VERB
easat-4310	64	22	on	on	ADP
easat-4310	64	23	data	data	NOUN
easat-4310	64	24	1080	1080	NUM
easat-4310	64	25	edelweiss	edelweiss	PROPN
easat-4310	64	26	applied	apply	VERB
easat-4310	64	27	science	science	NOUN
easat-4310	64	28	and	and	CCONJ
easat-4310	64	29	technology	technology	NOUN
easat-4310	64	30	issn	issn	PROPN
easat-4310	64	31	:	:	PUNCT
easat-4310	64	32	2576	2576	NUM
easat-4310	64	33	-	-	SYM
easat-4310	64	34	8484	8484	NUM
easat-4310	64	35	vol	vol	NOUN
easat-4310	64	36	.	.	PROPN
easat-4310	65	1	9	9	NUM
easat-4310	65	2	,	,	PUNCT
easat-4310	65	3	no	no	INTJ
easat-4310	65	4	.	.	NOUN
easat-4310	65	5	1	1	NUM
easat-4310	65	6	:	:	SYM
easat-4310	65	7	1078	1078	NUM
easat-4310	65	8	-	-	SYM
easat-4310	65	9	1085	1085	NUM
easat-4310	65	10	,	,	PUNCT
easat-4310	65	11	2025	2025	NUM
easat-4310	65	12	doi	doi	NOUN
easat-4310	65	13	:	:	PUNCT
easat-4310	65	14	10.55214/25768484.v9i1.4310	10.55214/25768484.v9i1.4310	NUM
easat-4310	65	15	©	©	PROPN
easat-4310	65	16	2025	2025	NUM
easat-4310	65	17	by	by	ADP
easat-4310	65	18	the	the	DET
easat-4310	65	19	authors	author	NOUN
easat-4310	65	20	;	;	PUNCT
easat-4310	65	21	licensee	licensee	NOUN
easat-4310	65	22	learning	learn	VERB
easat-4310	65	23	gate	gate	NOUN
easat-4310	65	24	distribution	distribution	NOUN
easat-4310	65	25	[	[	X
easat-4310	65	26	13	13	NUM
easat-4310	65	27	]	]	PUNCT
easat-4310	65	28	.	.	PUNCT
easat-4310	66	1	paired	pair	VERB
easat-4310	66	2	t	t	NOUN
easat-4310	66	3	-	-	PUNCT
easat-4310	66	4	tests	test	NOUN
easat-4310	66	5	were	be	AUX
easat-4310	66	6	performed	perform	VERB
easat-4310	66	7	to	to	PART
easat-4310	66	8	assess	assess	VERB
easat-4310	66	9	changes	change	NOUN
easat-4310	66	10	in	in	ADP
easat-4310	66	11	citrulline	citrulline	NOUN
easat-4310	66	12	levels	level	NOUN
easat-4310	66	13	before	before	ADP
easat-4310	66	14	and	and	CCONJ
easat-4310	66	15	after	after	ADP
easat-4310	66	16	chemotherapy	chemotherapy	NOUN
easat-4310	66	17	in	in	ADP
easat-4310	66	18	normally	normally	ADV
easat-4310	66	19	distributed	distribute	VERB
easat-4310	66	20	data	datum	NOUN
easat-4310	66	21	,	,	PUNCT
easat-4310	66	22	while	while	SCONJ
easat-4310	66	23	the	the	DET
easat-4310	66	24	wilcoxon	wilcoxon	NOUN
easat-4310	66	25	signed	sign	VERB
easat-4310	66	26	rank	rank	NOUN
easat-4310	66	27	test	test	NOUN
easat-4310	66	28	was	be	AUX
easat-4310	66	29	applied	apply	VERB
easat-4310	66	30	to	to	ADP
easat-4310	66	31	nonnormally	nonnormally	ADV
easat-4310	66	32	distributed	distribute	VERB
easat-4310	66	33	data	datum	NOUN
easat-4310	66	34	.	.	PUNCT
easat-4310	67	1	differences	difference	NOUN
easat-4310	67	2	between	between	ADP
easat-4310	67	3	risk	risk	NOUN
easat-4310	67	4	groups	group	NOUN
easat-4310	67	5	(	(	PUNCT
easat-4310	67	6	sr	sr	PROPN
easat-4310	67	7	vs.	vs.	X
easat-4310	67	8	hr	hr	PROPN
easat-4310	67	9	)	)	PUNCT
easat-4310	67	10	and	and	CCONJ
easat-4310	67	11	mucositis	mucositis	PROPN
easat-4310	67	12	grades	grade	NOUN
easat-4310	67	13	were	be	AUX
easat-4310	67	14	analyzed	analyze	VERB
easat-4310	67	15	to	to	PART
easat-4310	67	16	explore	explore	VERB
easat-4310	67	17	subgroup	subgroup	NOUN
easat-4310	67	18	-	-	PUNCT
easat-4310	67	19	specific	specific	ADJ
easat-4310	67	20	trends	trend	NOUN
easat-4310	67	21	.	.	PUNCT
easat-4310	68	1	a	a	DET
easat-4310	68	2	p	p	NOUN
easat-4310	68	3	-	-	PUNCT
easat-4310	68	4	value	value	NOUN
easat-4310	68	5	of	of	ADP
easat-4310	68	6	less	less	ADJ
easat-4310	68	7	than	than	ADP
easat-4310	68	8	0.05	0.05	NUM
easat-4310	68	9	was	be	AUX
easat-4310	68	10	considered	consider	VERB
easat-4310	68	11	statistically	statistically	ADV
easat-4310	68	12	significant	significant	ADJ
easat-4310	68	13	[	[	X
easat-4310	68	14	14	14	NUM
easat-4310	68	15	]	]	PUNCT
easat-4310	68	16	.	.	PUNCT
easat-4310	69	1	this	this	DET
easat-4310	69	2	methodological	methodological	ADJ
easat-4310	69	3	framework	framework	NOUN
easat-4310	69	4	ensures	ensure	VERB
easat-4310	69	5	the	the	DET
easat-4310	69	6	reliability	reliability	NOUN
easat-4310	69	7	and	and	CCONJ
easat-4310	69	8	validity	validity	NOUN
easat-4310	69	9	of	of	ADP
easat-4310	69	10	findings	finding	NOUN
easat-4310	69	11	,	,	PUNCT
easat-4310	69	12	allowing	allow	VERB
easat-4310	69	13	for	for	ADP
easat-4310	69	14	robust	robust	ADJ
easat-4310	69	15	conclusions	conclusion	NOUN
easat-4310	69	16	regarding	regard	VERB
easat-4310	69	17	the	the	DET
easat-4310	69	18	utility	utility	NOUN
easat-4310	69	19	of	of	ADP
easat-4310	69	20	citrulline	citrulline	NOUN
easat-4310	69	21	as	as	ADP
easat-4310	69	22	a	a	DET
easat-4310	69	23	biomarker	biomarker	NOUN
easat-4310	69	24	for	for	ADP
easat-4310	69	25	gi	gi	X
easat-4310	69	26	mucositis	mucositis	PROPN
easat-4310	69	27	in	in	ADP
easat-4310	69	28	pediatric	pediatric	ADJ
easat-4310	69	29	all	all	DET
easat-4310	69	30	patients	patient	NOUN
easat-4310	69	31	undergoing	undergo	VERB
easat-4310	69	32	hd	hd	NOUN
easat-4310	69	33	-	-	PUNCT
easat-4310	69	34	mtx	mtx	NOUN
easat-4310	69	35	chemotherapy	chemotherapy	NOUN
easat-4310	69	36	[	[	X
easat-4310	69	37	15	15	NUM
easat-4310	69	38	]	]	SYM
easat-4310	69	39	.	.	PUNCT
easat-4310	70	1	3	3	X
easat-4310	70	2	.	.	NOUN
easat-4310	70	3	results	result	VERB
easat-4310	70	4	the	the	DET
easat-4310	70	5	study	study	NOUN
easat-4310	70	6	included	include	VERB
easat-4310	70	7	a	a	DET
easat-4310	70	8	total	total	NOUN
easat-4310	70	9	of	of	ADP
easat-4310	70	10	34	34	NUM
easat-4310	70	11	pediatric	pediatric	ADJ
easat-4310	70	12	patients	patient	NOUN
easat-4310	70	13	diagnosed	diagnose	VERB
easat-4310	70	14	with	with	ADP
easat-4310	70	15	all	all	PRON
easat-4310	70	16	during	during	ADP
easat-4310	70	17	the	the	DET
easat-4310	70	18	consolidation	consolidation	NOUN
easat-4310	70	19	phase	phase	NOUN
easat-4310	70	20	.	.	PUNCT
easat-4310	71	1	the	the	DET
easat-4310	71	2	median	median	ADJ
easat-4310	71	3	age	age	NOUN
easat-4310	71	4	was	be	AUX
easat-4310	71	5	11	11	NUM
easat-4310	71	6	years	year	NOUN
easat-4310	71	7	,	,	PUNCT
easat-4310	71	8	with	with	ADP
easat-4310	71	9	an	an	DET
easat-4310	71	10	age	age	NOUN
easat-4310	71	11	range	range	NOUN
easat-4310	71	12	spanning	span	VERB
easat-4310	71	13	from	from	ADP
easat-4310	71	14	1	1	NUM
easat-4310	71	15	to	to	PART
easat-4310	71	16	18	18	NUM
easat-4310	71	17	years	year	NOUN
easat-4310	71	18	.	.	PUNCT
easat-4310	72	1	a	a	DET
easat-4310	72	2	male	male	ADJ
easat-4310	72	3	predominance	predominance	NOUN
easat-4310	72	4	was	be	AUX
easat-4310	72	5	observed	observe	VERB
easat-4310	72	6	,	,	PUNCT
easat-4310	72	7	comprising	comprise	VERB
easat-4310	72	8	73.5	73.5	NUM
easat-4310	72	9	%	%	NOUN
easat-4310	72	10	of	of	ADP
easat-4310	72	11	the	the	DET
easat-4310	72	12	study	study	NOUN
easat-4310	72	13	population	population	NOUN
easat-4310	72	14	.	.	PUNCT
easat-4310	73	1	nutritional	nutritional	ADJ
easat-4310	73	2	assessments	assessment	NOUN
easat-4310	73	3	revealed	reveal	VERB
easat-4310	73	4	that	that	SCONJ
easat-4310	73	5	38.2	38.2	NUM
easat-4310	73	6	%	%	NOUN
easat-4310	73	7	of	of	ADP
easat-4310	73	8	participants	participant	NOUN
easat-4310	73	9	had	have	VERB
easat-4310	73	10	normal	normal	ADJ
easat-4310	73	11	nutritional	nutritional	ADJ
easat-4310	73	12	status	status	NOUN
easat-4310	73	13	,	,	PUNCT
easat-4310	73	14	while	while	SCONJ
easat-4310	73	15	17.6	17.6	NUM
easat-4310	73	16	%	%	NOUN
easat-4310	73	17	were	be	AUX
easat-4310	73	18	undernourished	undernourish	VERB
easat-4310	73	19	,	,	PUNCT
easat-4310	73	20	26.6	26.6	NUM
easat-4310	73	21	%	%	NOUN
easat-4310	73	22	were	be	AUX
easat-4310	73	23	overnourished	overnourishe	VERB
easat-4310	73	24	,	,	PUNCT
easat-4310	73	25	and	and	CCONJ
easat-4310	73	26	17.6	17.6	NUM
easat-4310	73	27	%	%	NOUN
easat-4310	73	28	were	be	AUX
easat-4310	73	29	classified	classify	VERB
easat-4310	73	30	as	as	ADP
easat-4310	73	31	obese	obese	ADJ
easat-4310	73	32	.	.	PUNCT
easat-4310	74	1	the	the	DET
easat-4310	74	2	baseline	baseline	PROPN
easat-4310	74	3	characteristics	characteristic	NOUN
easat-4310	74	4	of	of	ADP
easat-4310	74	5	pediatric	pediatric	ADJ
easat-4310	74	6	all	all	DET
easat-4310	74	7	patients	patient	NOUN
easat-4310	74	8	stratified	stratify	VERB
easat-4310	74	9	by	by	ADP
easat-4310	74	10	mucositis	mucositis	NOUN
easat-4310	74	11	grade	grade	NOUN
easat-4310	74	12	are	be	AUX
easat-4310	74	13	summarized	summarize	VERB
easat-4310	74	14	in	in	ADP
easat-4310	74	15	table	table	NOUN
easat-4310	74	16	1	1	NUM
easat-4310	74	17	.	.	PUNCT
easat-4310	74	18	notable	notable	ADJ
easat-4310	74	19	trends	trend	NOUN
easat-4310	74	20	include	include	VERB
easat-4310	74	21	a	a	DET
easat-4310	74	22	higher	high	ADJ
easat-4310	74	23	prevalence	prevalence	NOUN
easat-4310	74	24	of	of	ADP
easat-4310	74	25	mucositis	mucositis	PROPN
easat-4310	74	26	in	in	ADP
easat-4310	74	27	standard	standard	ADJ
easat-4310	74	28	risk	risk	NOUN
easat-4310	74	29	patients	patient	NOUN
easat-4310	74	30	and	and	CCONJ
easat-4310	74	31	variable	variable	ADJ
easat-4310	74	32	nutritional	nutritional	ADJ
easat-4310	74	33	statuses	status	NOUN
easat-4310	74	34	across	across	ADP
easat-4310	74	35	groups	group	NOUN
easat-4310	74	36	.	.	PUNCT
easat-4310	75	1	table	table	NOUN
easat-4310	75	2	1	1	NUM
easat-4310	75	3	.	.	PUNCT
easat-4310	75	4	baseline	baseline	PROPN
easat-4310	75	5	characteristics	characteristic	NOUN
easat-4310	75	6	and	and	CCONJ
easat-4310	75	7	mucositis	mucositis	NOUN
easat-4310	75	8	grades	grade	NOUN
easat-4310	75	9	of	of	ADP
easat-4310	75	10	pediatric	pediatric	ADJ
easat-4310	75	11	all	all	DET
easat-4310	75	12	patients	patient	NOUN
easat-4310	75	13	undergoing	undergo	VERB
easat-4310	75	14	hd	hd	NOUN
easat-4310	75	15	-	-	PUNCT
easat-4310	75	16	mtx	mtx	NOUN
easat-4310	75	17	chemotherapy	chemotherapy	NOUN
easat-4310	75	18	.	.	PUNCT
easat-4310	76	1	variable	variable	ADJ
easat-4310	76	2	total	total	NOUN
easat-4310	76	3	(	(	PUNCT
easat-4310	76	4	n	n	NOUN
easat-4310	76	5	=	=	SYM
easat-4310	76	6	34	34	NUM
easat-4310	76	7	)	)	PUNCT
easat-4310	76	8	grade	grade	NOUN
easat-4310	76	9	1	1	NUM
easat-4310	76	10	mucositis	mucositis	NOUN
easat-4310	76	11	(	(	PUNCT
easat-4310	76	12	n	n	NOUN
easat-4310	76	13	=	=	SYM
easat-4310	76	14	16	16	NUM
easat-4310	76	15	)	)	PUNCT
easat-4310	76	16	grade	grade	NOUN
easat-4310	76	17	2	2	NUM
easat-4310	76	18	mucositis	mucositis	NOUN
easat-4310	76	19	(	(	PUNCT
easat-4310	76	20	n	n	NOUN
easat-4310	76	21	=	=	NUM
easat-4310	76	22	12	12	NUM
easat-4310	76	23	)	)	PUNCT
easat-4310	76	24	no	no	DET
easat-4310	76	25	mucositis	mucositis	NOUN
easat-4310	76	26	(	(	PUNCT
easat-4310	76	27	n	n	NOUN
easat-4310	76	28	=	=	SYM
easat-4310	76	29	6	6	NUM
easat-4310	76	30	)	)	PUNCT
easat-4310	76	31	median	median	ADJ
easat-4310	76	32	age	age	NOUN
easat-4310	76	33	(	(	PUNCT
easat-4310	76	34	years	year	NOUN
easat-4310	76	35	)	)	PUNCT
easat-4310	76	36	11	11	NUM
easat-4310	76	37	(	(	PUNCT
easat-4310	76	38	1	1	NUM
easat-4310	76	39	-	-	SYM
easat-4310	76	40	18	18	NUM
easat-4310	76	41	)	)	PUNCT
easat-4310	76	42	10.5	10.5	NUM
easat-4310	76	43	(	(	PUNCT
easat-4310	76	44	2	2	NUM
easat-4310	76	45	-	-	SYM
easat-4310	76	46	18	18	NUM
easat-4310	76	47	)	)	PUNCT
easat-4310	76	48	11.0	11.0	NUM
easat-4310	76	49	(	(	PUNCT
easat-4310	76	50	1	1	NUM
easat-4310	76	51	-	-	SYM
easat-4310	76	52	15	15	NUM
easat-4310	76	53	)	)	PUNCT
easat-4310	76	54	12.0	12.0	NUM
easat-4310	76	55	(	(	PUNCT
easat-4310	76	56	5	5	NUM
easat-4310	76	57	-	-	SYM
easat-4310	76	58	17	17	NUM
easat-4310	76	59	)	)	PUNCT
easat-4310	76	60	sex	sex	NOUN
easat-4310	76	61	(	(	PUNCT
easat-4310	76	62	male	male	NOUN
easat-4310	76	63	,	,	PUNCT
easat-4310	76	64	%	%	INTJ
easat-4310	76	65	)	)	PUNCT
easat-4310	76	66	25	25	NUM
easat-4310	76	67	(	(	PUNCT
easat-4310	76	68	73.5	73.5	NUM
easat-4310	76	69	%	%	NOUN
easat-4310	76	70	)	)	PUNCT
easat-4310	76	71	12	12	NUM
easat-4310	76	72	(	(	PUNCT
easat-4310	76	73	75.0	75.0	NUM
easat-4310	76	74	%	%	NOUN
easat-4310	76	75	)	)	PUNCT
easat-4310	76	76	9	9	NUM
easat-4310	76	77	(	(	PUNCT
easat-4310	76	78	75.0	75.0	NUM
easat-4310	76	79	%	%	NOUN
easat-4310	76	80	)	)	PUNCT
easat-4310	76	81	4	4	NUM
easat-4310	76	82	(	(	PUNCT
easat-4310	76	83	66.7	66.7	NUM
easat-4310	76	84	%	%	NOUN
easat-4310	76	85	)	)	PUNCT
easat-4310	76	86	nutritional	nutritional	ADJ
easat-4310	76	87	status	status	NOUN
easat-4310	76	88	normal	normal	ADJ
easat-4310	76	89	13	13	NUM
easat-4310	76	90	(	(	PUNCT
easat-4310	76	91	38.2	38.2	NUM
easat-4310	76	92	%	%	NOUN
easat-4310	76	93	)	)	PUNCT
easat-4310	76	94	7	7	NUM
easat-4310	76	95	(	(	PUNCT
easat-4310	76	96	43.8	43.8	NUM
easat-4310	76	97	%	%	NOUN
easat-4310	76	98	)	)	PUNCT
easat-4310	76	99	4	4	NUM
easat-4310	76	100	(	(	PUNCT
easat-4310	76	101	33.3	33.3	NUM
easat-4310	76	102	%	%	NOUN
easat-4310	76	103	)	)	PUNCT
easat-4310	76	104	2	2	NUM
easat-4310	76	105	(	(	PUNCT
easat-4310	76	106	33.3	33.3	NUM
easat-4310	76	107	%	%	NOUN
easat-4310	76	108	)	)	PUNCT
easat-4310	76	109	undernourished	undernourish	VERB
easat-4310	76	110	6	6	NUM
easat-4310	76	111	(	(	PUNCT
easat-4310	76	112	17.6	17.6	NUM
easat-4310	76	113	%	%	NOUN
easat-4310	76	114	)	)	PUNCT
easat-4310	76	115	3	3	NUM
easat-4310	76	116	(	(	PUNCT
easat-4310	76	117	18.8	18.8	NUM
easat-4310	76	118	%	%	NOUN
easat-4310	76	119	)	)	PUNCT
easat-4310	76	120	2	2	NUM
easat-4310	76	121	(	(	PUNCT
easat-4310	76	122	16.7	16.7	NUM
easat-4310	76	123	%	%	NOUN
easat-4310	76	124	)	)	PUNCT
easat-4310	76	125	1	1	NUM
easat-4310	76	126	(	(	PUNCT
easat-4310	76	127	16.7	16.7	NUM
easat-4310	76	128	%	%	NOUN
easat-4310	76	129	)	)	PUNCT
easat-4310	76	130	overnourished	overnourishe	VERB
easat-4310	76	131	9	9	NUM
easat-4310	76	132	(	(	PUNCT
easat-4310	76	133	26.6	26.6	NUM
easat-4310	76	134	%	%	NOUN
easat-4310	76	135	)	)	PUNCT
easat-4310	76	136	4	4	NUM
easat-4310	76	137	(	(	PUNCT
easat-4310	76	138	25.0	25.0	NUM
easat-4310	76	139	%	%	NOUN
easat-4310	76	140	)	)	PUNCT
easat-4310	76	141	3	3	NUM
easat-4310	76	142	(	(	PUNCT
easat-4310	76	143	25.0	25.0	NUM
easat-4310	76	144	%	%	NOUN
easat-4310	76	145	)	)	PUNCT
easat-4310	76	146	2	2	NUM
easat-4310	76	147	(	(	PUNCT
easat-4310	76	148	33.3	33.3	NUM
easat-4310	76	149	%	%	NOUN
easat-4310	76	150	)	)	PUNCT
easat-4310	77	1	obese	obese	ADV
easat-4310	77	2	6	6	NUM
easat-4310	77	3	(	(	PUNCT
easat-4310	77	4	17.6	17.6	NUM
easat-4310	77	5	%	%	NOUN
easat-4310	77	6	)	)	PUNCT
easat-4310	77	7	2	2	NUM
easat-4310	77	8	(	(	PUNCT
easat-4310	77	9	12.5	12.5	NUM
easat-4310	77	10	%	%	NOUN
easat-4310	77	11	)	)	PUNCT
easat-4310	77	12	3	3	NUM
easat-4310	77	13	(	(	PUNCT
easat-4310	77	14	25.0	25.0	NUM
easat-4310	77	15	%	%	NOUN
easat-4310	77	16	)	)	PUNCT
easat-4310	77	17	1	1	NUM
easat-4310	77	18	(	(	PUNCT
easat-4310	77	19	16.7	16.7	NUM
easat-4310	77	20	%	%	NOUN
easat-4310	77	21	)	)	PUNCT
easat-4310	77	22	risk	risk	NOUN
easat-4310	77	23	group	group	NOUN
easat-4310	77	24	standard	standard	ADJ
easat-4310	77	25	risk	risk	NOUN
easat-4310	77	26	(	(	PUNCT
easat-4310	77	27	sr	sr	PROPN
easat-4310	77	28	)	)	PUNCT
easat-4310	77	29	20	20	NUM
easat-4310	77	30	(	(	PUNCT
easat-4310	77	31	58.8	58.8	NUM
easat-4310	77	32	%	%	NOUN
easat-4310	77	33	)	)	PUNCT
easat-4310	77	34	10	10	NUM
easat-4310	77	35	(	(	PUNCT
easat-4310	77	36	62.5	62.5	NUM
easat-4310	77	37	%	%	NOUN
easat-4310	77	38	)	)	PUNCT
easat-4310	77	39	6	6	NUM
easat-4310	77	40	(	(	PUNCT
easat-4310	77	41	50.0	50.0	NUM
easat-4310	77	42	%	%	NOUN
easat-4310	77	43	)	)	PUNCT
easat-4310	77	44	4	4	NUM
easat-4310	77	45	(	(	PUNCT
easat-4310	77	46	66.7	66.7	NUM
easat-4310	77	47	%	%	NOUN
easat-4310	77	48	)	)	PUNCT
easat-4310	77	49	high	high	ADJ
easat-4310	77	50	risk	risk	NOUN
easat-4310	77	51	(	(	PUNCT
easat-4310	77	52	hr	hr	NOUN
easat-4310	77	53	)	)	PUNCT
easat-4310	77	54	14	14	NUM
easat-4310	77	55	(	(	PUNCT
easat-4310	77	56	41.2	41.2	NUM
easat-4310	77	57	%	%	NOUN
easat-4310	77	58	)	)	PUNCT
easat-4310	77	59	6	6	NUM
easat-4310	77	60	(	(	PUNCT
easat-4310	77	61	37.5	37.5	NUM
easat-4310	77	62	%	%	NOUN
easat-4310	77	63	)	)	PUNCT
easat-4310	77	64	6	6	NUM
easat-4310	77	65	(	(	PUNCT
easat-4310	77	66	50.0	50.0	NUM
easat-4310	77	67	%	%	NOUN
easat-4310	77	68	)	)	PUNCT
easat-4310	77	69	2	2	NUM
easat-4310	77	70	(	(	PUNCT
easat-4310	77	71	33.3	33.3	NUM
easat-4310	77	72	%	%	NOUN
easat-4310	77	73	)	)	PUNCT
easat-4310	78	1	gi	gi	VERB
easat-4310	78	2	mucositis	mucositis	PROPN
easat-4310	78	3	was	be	AUX
easat-4310	78	4	confirmed	confirm	VERB
easat-4310	78	5	in	in	ADP
easat-4310	78	6	82.4	82.4	NUM
easat-4310	78	7	%	%	NOUN
easat-4310	78	8	of	of	ADP
easat-4310	78	9	the	the	DET
easat-4310	78	10	participants	participant	NOUN
easat-4310	78	11	.	.	PUNCT
easat-4310	79	1	among	among	ADP
easat-4310	79	2	these	these	PRON
easat-4310	79	3	,	,	PUNCT
easat-4310	79	4	47.1	47.1	NUM
easat-4310	79	5	%	%	NOUN
easat-4310	79	6	experienced	experienced	ADJ
easat-4310	79	7	grade	grade	NOUN
easat-4310	79	8	1	1	NUM
easat-4310	79	9	mucositis	mucositis	NOUN
easat-4310	79	10	,	,	PUNCT
easat-4310	79	11	while	while	SCONJ
easat-4310	79	12	35.3	35.3	NUM
easat-4310	79	13	%	%	NOUN
easat-4310	79	14	exhibited	exhibit	VERB
easat-4310	79	15	grade	grade	NOUN
easat-4310	79	16	2	2	NUM
easat-4310	79	17	mucositis	mucositis	NOUN
easat-4310	79	18	.	.	PUNCT
easat-4310	80	1	no	no	DET
easat-4310	80	2	cases	case	NOUN
easat-4310	80	3	of	of	ADP
easat-4310	80	4	grade	grade	NOUN
easat-4310	80	5	3	3	NUM
easat-4310	80	6	or	or	CCONJ
easat-4310	80	7	grade	grade	NOUN
easat-4310	80	8	4	4	NUM
easat-4310	80	9	mucositis	mucositis	NOUN
easat-4310	80	10	were	be	AUX
easat-4310	80	11	observed	observe	VERB
easat-4310	80	12	in	in	ADP
easat-4310	80	13	this	this	DET
easat-4310	80	14	cohort	cohort	NOUN
easat-4310	80	15	,	,	PUNCT
easat-4310	80	16	indicating	indicate	VERB
easat-4310	80	17	a	a	DET
easat-4310	80	18	predominantly	predominantly	ADV
easat-4310	80	19	mild	mild	ADJ
easat-4310	80	20	to	to	ADP
easat-4310	80	21	moderate	moderate	ADJ
easat-4310	80	22	severity	severity	NOUN
easat-4310	80	23	of	of	ADP
easat-4310	80	24	mucosal	mucosal	ADJ
easat-4310	80	25	injury	injury	NOUN
easat-4310	80	26	.	.	PUNCT
easat-4310	81	1	3.1	3.1	NUM
easat-4310	81	2	.	.	PUNCT
easat-4310	81	3	citrulline	citrulline	NOUN
easat-4310	81	4	level	level	NOUN
easat-4310	81	5	changes	change	NOUN
easat-4310	81	6	overall	overall	ADV
easat-4310	81	7	,	,	PUNCT
easat-4310	81	8	serum	serum	ADJ
easat-4310	81	9	citrulline	citrulline	NOUN
easat-4310	81	10	levels	level	NOUN
easat-4310	81	11	demonstrated	demonstrate	VERB
easat-4310	81	12	a	a	DET
easat-4310	81	13	non	non	ADJ
easat-4310	81	14	-	-	ADJ
easat-4310	81	15	significant	significant	ADJ
easat-4310	81	16	change	change	NOUN
easat-4310	81	17	following	follow	VERB
easat-4310	81	18	hd	hd	NOUN
easat-4310	81	19	-	-	PUNCT
easat-4310	81	20	mtx	mtx	NOUN
easat-4310	81	21	chemotherapy	chemotherapy	NOUN
easat-4310	81	22	.	.	PUNCT
easat-4310	82	1	the	the	DET
easat-4310	82	2	mean	mean	ADJ
easat-4310	82	3	pre	pre	ADJ
easat-4310	82	4	-	-	ADJ
easat-4310	82	5	treatment	treatment	ADJ
easat-4310	82	6	citrulline	citrulline	NOUN
easat-4310	82	7	level	level	NOUN
easat-4310	82	8	was	be	AUX
easat-4310	82	9	3.56	3.56	NUM
easat-4310	82	10	±	±	NUM
easat-4310	82	11	0.07	0.07	NUM
easat-4310	82	12	µmol	µmol	ADP
easat-4310	82	13	/	/	SYM
easat-4310	82	14	l	l	NOUN
easat-4310	82	15	,	,	PUNCT
easat-4310	82	16	compared	compare	VERB
easat-4310	82	17	to	to	ADP
easat-4310	82	18	3.30	3.30	NUM
easat-4310	82	19	±	±	NUM
easat-4310	82	20	0.07	0.07	NUM
easat-4310	82	21	µmol	µmol	ADP
easat-4310	82	22	/	/	SYM
easat-4310	82	23	l	l	NOUN
easat-4310	82	24	post	post	NOUN
easat-4310	82	25	-	-	NOUN
easat-4310	82	26	treatment	treatment	NOUN
easat-4310	82	27	(	(	PUNCT
easat-4310	82	28	p	p	X
easat-4310	82	29	=	=	NOUN
easat-4310	82	30	0.214	0.214	NUM
easat-4310	82	31	)	)	PUNCT
easat-4310	82	32	.	.	PUNCT
easat-4310	83	1	despite	despite	SCONJ
easat-4310	83	2	the	the	DET
easat-4310	83	3	lack	lack	NOUN
easat-4310	83	4	of	of	ADP
easat-4310	83	5	a	a	DET
easat-4310	83	6	significant	significant	ADJ
easat-4310	83	7	overall	overall	ADJ
easat-4310	83	8	change	change	NOUN
easat-4310	83	9	,	,	PUNCT
easat-4310	83	10	subgroup	subgroup	NOUN
easat-4310	83	11	analyses	analysis	NOUN
easat-4310	83	12	revealed	reveal	VERB
easat-4310	83	13	notable	notable	ADJ
easat-4310	83	14	trends	trend	NOUN
easat-4310	83	15	based	base	VERB
easat-4310	83	16	on	on	ADP
easat-4310	83	17	risk	risk	NOUN
easat-4310	83	18	stratification	stratification	NOUN
easat-4310	83	19	and	and	CCONJ
easat-4310	83	20	mucositis	mucositis	NOUN
easat-4310	83	21	severity	severity	NOUN
easat-4310	83	22	.	.	PUNCT
easat-4310	84	1	in	in	ADP
easat-4310	84	2	the	the	DET
easat-4310	84	3	standard	standard	ADJ
easat-4310	84	4	risk	risk	NOUN
easat-4310	84	5	(	(	PUNCT
easat-4310	84	6	sr	sr	PROPN
easat-4310	84	7	)	)	PUNCT
easat-4310	84	8	group	group	NOUN
easat-4310	84	9	,	,	PUNCT
easat-4310	84	10	citrulline	citrulline	NOUN
easat-4310	84	11	levels	level	NOUN
easat-4310	84	12	exhibited	exhibit	VERB
easat-4310	84	13	a	a	DET
easat-4310	84	14	consistent	consistent	ADJ
easat-4310	84	15	decrease	decrease	NOUN
easat-4310	84	16	postchemotherapy	postchemotherapy	NOUN
easat-4310	84	17	,	,	PUNCT
easat-4310	84	18	aligning	align	VERB
easat-4310	84	19	with	with	ADP
easat-4310	84	20	the	the	DET
easat-4310	84	21	expected	expect	VERB
easat-4310	84	22	pattern	pattern	NOUN
easat-4310	84	23	of	of	ADP
easat-4310	84	24	mucosal	mucosal	ADJ
easat-4310	84	25	damage	damage	NOUN
easat-4310	84	26	.	.	PUNCT
easat-4310	85	1	this	this	DET
easat-4310	85	2	decline	decline	NOUN
easat-4310	85	3	supports	support	VERB
easat-4310	85	4	the	the	DET
easat-4310	85	5	role	role	NOUN
easat-4310	85	6	of	of	ADP
easat-4310	85	7	citrulline	citrulline	NOUN
easat-4310	85	8	as	as	ADP
easat-4310	85	9	a	a	DET
easat-4310	85	10	biomarker	biomarker	NOUN
easat-4310	85	11	for	for	ADP
easat-4310	85	12	detecting	detect	VERB
easat-4310	85	13	enterocyte	enterocyte	NOUN
easat-4310	85	14	loss	loss	NOUN
easat-4310	85	15	in	in	ADP
easat-4310	85	16	this	this	DET
easat-4310	85	17	subset	subset	NOUN
easat-4310	85	18	of	of	ADP
easat-4310	85	19	patients	patient	NOUN
easat-4310	85	20	.	.	PUNCT
easat-4310	86	1	conversely	conversely	ADV
easat-4310	86	2	,	,	PUNCT
easat-4310	86	3	the	the	DET
easat-4310	86	4	high	high	ADJ
easat-4310	86	5	risk	risk	NOUN
easat-4310	86	6	(	(	PUNCT
easat-4310	86	7	hr	hr	NOUN
easat-4310	86	8	)	)	PUNCT
easat-4310	86	9	group	group	NOUN
easat-4310	86	10	demonstrated	demonstrate	VERB
easat-4310	86	11	a	a	DET
easat-4310	86	12	significant	significant	ADJ
easat-4310	86	13	increase	increase	NOUN
easat-4310	86	14	in	in	ADP
easat-4310	86	15	citrulline	citrulline	NOUN
easat-4310	86	16	levels	level	NOUN
easat-4310	86	17	following	follow	VERB
easat-4310	86	18	treatment	treatment	NOUN
easat-4310	86	19	(	(	PUNCT
easat-4310	86	20	3.07	3.07	NUM
easat-4310	86	21	±	±	NUM
easat-4310	86	22	1.42	1.42	NUM
easat-4310	86	23	µmol	µmol	ADP
easat-4310	86	24	/	/	SYM
easat-4310	86	25	l	l	NOUN
easat-4310	86	26	pre	pre	NOUN
easat-4310	86	27	-	-	NOUN
easat-4310	86	28	treatment	treatment	NOUN
easat-4310	86	29	vs.	vs.	ADP
easat-4310	86	30	4.17	4.17	NUM
easat-4310	86	31	±	±	NUM
easat-4310	86	32	2.38	2.38	NUM
easat-4310	86	33	µmol	µmol	ADP
easat-4310	86	34	/	/	SYM
easat-4310	86	35	l	l	NOUN
easat-4310	86	36	post	post	NOUN
easat-4310	86	37	-	-	NOUN
easat-4310	86	38	treatment	treatment	NOUN
easat-4310	86	39	;	;	PUNCT
easat-4310	86	40	p	p	X
easat-4310	86	41	=	=	NOUN
easat-4310	86	42	0.049	0.049	NUM
easat-4310	86	43	)	)	PUNCT
easat-4310	86	44	,	,	PUNCT
easat-4310	86	45	suggesting	suggest	VERB
easat-4310	86	46	an	an	DET
easat-4310	86	47	adaptive	adaptive	ADJ
easat-4310	86	48	or	or	CCONJ
easat-4310	86	49	compensatory	compensatory	ADJ
easat-4310	86	50	mechanism	mechanism	NOUN
easat-4310	86	51	.	.	PUNCT
easat-4310	87	1	table	table	NOUN
easat-4310	87	2	2	2	NUM
easat-4310	87	3	illustrates	illustrate	VERB
easat-4310	87	4	the	the	DET
easat-4310	87	5	changes	change	NOUN
easat-4310	87	6	in	in	ADP
easat-4310	87	7	citrulline	citrulline	NOUN
easat-4310	87	8	levels	level	NOUN
easat-4310	87	9	preand	preand	VERB
easat-4310	87	10	post	post	ADJ
easat-4310	87	11	-	-	ADJ
easat-4310	87	12	hd	hd	ADJ
easat-4310	87	13	-	-	PUNCT
easat-4310	87	14	mtx	mtx	NOUN
easat-4310	87	15	chemotherapy	chemotherapy	NOUN
easat-4310	87	16	,	,	PUNCT
easat-4310	87	17	with	with	ADP
easat-4310	87	18	significant	significant	ADJ
easat-4310	87	19	increases	increase	NOUN
easat-4310	87	20	observed	observe	VERB
easat-4310	87	21	in	in	ADP
easat-4310	87	22	the	the	DET
easat-4310	87	23	hr	hr	NOUN
easat-4310	87	24	group	group	NOUN
easat-4310	87	25	.	.	PUNCT
easat-4310	88	1	table	table	NOUN
easat-4310	88	2	2	2	NUM
easat-4310	88	3	.	.	PUNCT
easat-4310	88	4	citrulline	citrulline	NOUN
easat-4310	88	5	levels	level	NOUN
easat-4310	88	6	preand	preand	VERB
easat-4310	88	7	post	post	ADJ
easat-4310	88	8	-	-	ADJ
easat-4310	88	9	hd	hd	ADJ
easat-4310	88	10	-	-	PUNCT
easat-4310	88	11	mtx	mtx	NOUN
easat-4310	88	12	chemotherapy	chemotherapy	NOUN
easat-4310	88	13	.	.	PUNCT
easat-4310	89	1	group	group	NOUN
easat-4310	89	2	pre	pre	ADJ
easat-4310	89	3	-	-	ADJ
easat-4310	89	4	treatment	treatment	ADJ
easat-4310	89	5	citrulline	citrulline	NOUN
easat-4310	89	6	(	(	PUNCT
easat-4310	89	7	nmol	nmol	NOUN
easat-4310	89	8	/	/	SYM
easat-4310	89	9	l	l	NOUN
easat-4310	89	10	)	)	PUNCT
easat-4310	89	11	post	post	ADJ
easat-4310	89	12	-	-	ADJ
easat-4310	89	13	treatment	treatment	ADJ
easat-4310	89	14	citrulline	citrulline	NOUN
easat-4310	89	15	(	(	PUNCT
easat-4310	89	16	nmol	nmol	NOUN
easat-4310	89	17	/	/	SYM
easat-4310	89	18	l	l	NOUN
easat-4310	89	19	)	)	PUNCT
easat-4310	89	20	p	p	NOUN
easat-4310	89	21	-	-	PUNCT
easat-4310	89	22	value	value	NOUN
easat-4310	89	23	1081	1081	NUM
easat-4310	89	24	edelweiss	edelweiss	PROPN
easat-4310	89	25	applied	apply	VERB
easat-4310	89	26	science	science	NOUN
easat-4310	89	27	and	and	CCONJ
easat-4310	89	28	technology	technology	NOUN
easat-4310	89	29	issn	issn	PROPN
easat-4310	89	30	:	:	PUNCT
easat-4310	89	31	2576	2576	NUM
easat-4310	89	32	-	-	SYM
easat-4310	89	33	8484	8484	NUM
easat-4310	89	34	vol	vol	NOUN
easat-4310	89	35	.	.	PROPN
easat-4310	90	1	9	9	NUM
easat-4310	90	2	,	,	PUNCT
easat-4310	90	3	no	no	INTJ
easat-4310	90	4	.	.	NOUN
easat-4310	90	5	1	1	NUM
easat-4310	90	6	:	:	SYM
easat-4310	90	7	1078	1078	NUM
easat-4310	90	8	-	-	SYM
easat-4310	90	9	1085	1085	NUM
easat-4310	90	10	,	,	PUNCT
easat-4310	90	11	2025	2025	NUM
easat-4310	90	12	doi	doi	NOUN
easat-4310	90	13	:	:	PUNCT
easat-4310	90	14	10.55214/25768484.v9i1.4310	10.55214/25768484.v9i1.4310	NUM
easat-4310	90	15	©	©	PROPN
easat-4310	90	16	2025	2025	NUM
easat-4310	90	17	by	by	ADP
easat-4310	90	18	the	the	DET
easat-4310	90	19	authors	author	NOUN
easat-4310	90	20	;	;	PUNCT
easat-4310	90	21	licensee	licensee	PROPN
easat-4310	90	22	learning	learning	NOUN
easat-4310	90	23	gate	gate	VERB
easat-4310	90	24	all	all	DET
easat-4310	90	25	patients	patient	NOUN
easat-4310	90	26	3.56	3.56	NUM
easat-4310	90	27	(	(	PUNCT
easat-4310	90	28	0.07	0.07	NUM
easat-4310	90	29	-	-	SYM
easat-4310	90	30	5.84	5.84	NUM
easat-4310	90	31	)	)	PUNCT
easat-4310	90	32	3.30	3.30	NUM
easat-4310	90	33	(	(	PUNCT
easat-4310	90	34	0.07	0.07	NUM
easat-4310	90	35	-	-	SYM
easat-4310	90	36	12.99	12.99	NUM
easat-4310	90	37	)	)	PUNCT
easat-4310	90	38	0.214	0.214	NUM
easat-4310	90	39	standard	standard	ADJ
easat-4310	90	40	risk	risk	NOUN
easat-4310	90	41	(	(	PUNCT
easat-4310	90	42	sr	sr	PROPN
easat-4310	90	43	)	)	PUNCT
easat-4310	90	44	3.67	3.67	NUM
easat-4310	90	45	(	(	PUNCT
easat-4310	90	46	1.06	1.06	NUM
easat-4310	90	47	-	-	SYM
easat-4310	90	48	5.7	5.7	NUM
easat-4310	90	49	)	)	PUNCT
easat-4310	90	50	2.71	2.71	NUM
easat-4310	90	51	(	(	PUNCT
easat-4310	90	52	0.07	0.07	NUM
easat-4310	90	53	-	-	SYM
easat-4310	90	54	12.99	12.99	NUM
easat-4310	90	55	)	)	PUNCT
easat-4310	90	56	0.906	0.906	NUM
easat-4310	90	57	high	high	ADJ
easat-4310	90	58	risk	risk	NOUN
easat-4310	90	59	(	(	PUNCT
easat-4310	90	60	hr	hr	NOUN
easat-4310	90	61	)	)	PUNCT
easat-4310	90	62	3.07	3.07	NUM
easat-4310	90	63	(	(	PUNCT
easat-4310	90	64	±	±	NOUN
easat-4310	90	65	1.42	1.42	NUM
easat-4310	90	66	)	)	PUNCT
easat-4310	90	67	4.17	4.17	NUM
easat-4310	90	68	(	(	PUNCT
easat-4310	90	69	±	±	NOUN
easat-4310	90	70	2.38	2.38	NUM
easat-4310	90	71	)	)	PUNCT
easat-4310	90	72	0.049	0.049	NUM
easat-4310	90	73	*	*	PUNCT
easat-4310	90	74	note	note	NOUN
easat-4310	90	75	:	:	PUNCT
easat-4310	90	76	*	*	PUNCT
easat-4310	90	77	statistically	statistically	ADV
easat-4310	90	78	significant	significant	ADJ
easat-4310	90	79	,	,	PUNCT
easat-4310	90	80	with	with	ADP
easat-4310	90	81	p	p	NOUN
easat-4310	90	82	-	-	PUNCT
easat-4310	90	83	value	value	NOUN
easat-4310	90	84	<	<	X
easat-4310	90	85	0.05	0.05	NUM
easat-4310	90	86	.	.	PUNCT
easat-4310	91	1	when	when	SCONJ
easat-4310	91	2	stratified	stratify	VERB
easat-4310	91	3	by	by	ADP
easat-4310	91	4	mucositis	mucositis	PROPN
easat-4310	91	5	grade	grade	NOUN
easat-4310	91	6	,	,	PUNCT
easat-4310	91	7	patients	patient	NOUN
easat-4310	91	8	with	with	ADP
easat-4310	91	9	grade	grade	NOUN
easat-4310	91	10	1	1	NUM
easat-4310	91	11	mucositis	mucositis	NOUN
easat-4310	91	12	exhibited	exhibit	VERB
easat-4310	91	13	a	a	DET
easat-4310	91	14	significant	significant	ADJ
easat-4310	91	15	rise	rise	NOUN
easat-4310	91	16	in	in	ADP
easat-4310	91	17	citrulline	citrulline	NOUN
easat-4310	91	18	levels	level	NOUN
easat-4310	91	19	(	(	PUNCT
easat-4310	91	20	3.82	3.82	NUM
easat-4310	91	21	±	±	NUM
easat-4310	91	22	1.06	1.06	NUM
easat-4310	91	23	µmol	µmol	ADP
easat-4310	91	24	/	/	SYM
easat-4310	91	25	l	l	NOUN
easat-4310	91	26	pre	pre	NOUN
easat-4310	91	27	-	-	NOUN
easat-4310	91	28	treatment	treatment	NOUN
easat-4310	91	29	vs.	vs.	ADP
easat-4310	91	30	3.95	3.95	NUM
easat-4310	91	31	±	±	NUM
easat-4310	91	32	1.14	1.14	NUM
easat-4310	91	33	µmol	µmol	ADP
easat-4310	91	34	/	/	SYM
easat-4310	91	35	l	l	NOUN
easat-4310	91	36	post	post	NOUN
easat-4310	91	37	-	-	NOUN
easat-4310	91	38	treatment	treatment	NOUN
easat-4310	91	39	;	;	PUNCT
easat-4310	91	40	p	p	X
easat-4310	91	41	=	=	NOUN
easat-4310	91	42	0.036	0.036	NUM
easat-4310	91	43	)	)	PUNCT
easat-4310	91	44	,	,	PUNCT
easat-4310	91	45	potentially	potentially	ADV
easat-4310	91	46	reflecting	reflect	VERB
easat-4310	91	47	early	early	ADJ
easat-4310	91	48	-	-	PUNCT
easat-4310	91	49	phase	phase	NOUN
easat-4310	91	50	enterocyte	enterocyte	NOUN
easat-4310	91	51	recovery	recovery	NOUN
easat-4310	91	52	.	.	PUNCT
easat-4310	92	1	in	in	ADP
easat-4310	92	2	contrast	contrast	NOUN
easat-4310	92	3	,	,	PUNCT
easat-4310	92	4	patients	patient	NOUN
easat-4310	92	5	with	with	ADP
easat-4310	92	6	grade	grade	NOUN
easat-4310	92	7	2	2	NUM
easat-4310	92	8	mucositis	mucositis	NOUN
easat-4310	92	9	showed	show	VERB
easat-4310	92	10	no	no	DET
easat-4310	92	11	significant	significant	ADJ
easat-4310	92	12	change	change	NOUN
easat-4310	92	13	in	in	ADP
easat-4310	92	14	citrulline	citrulline	NOUN
easat-4310	92	15	levels	level	NOUN
easat-4310	92	16	,	,	PUNCT
easat-4310	92	17	likely	likely	ADJ
easat-4310	92	18	due	due	ADP
easat-4310	92	19	to	to	ADP
easat-4310	92	20	the	the	DET
easat-4310	92	21	severity	severity	NOUN
easat-4310	92	22	of	of	ADP
easat-4310	92	23	mucosal	mucosal	ADJ
easat-4310	92	24	injury	injury	NOUN
easat-4310	92	25	overwhelming	overwhelming	ADJ
easat-4310	92	26	regenerative	regenerative	ADJ
easat-4310	92	27	capacity	capacity	NOUN
easat-4310	92	28	.	.	PUNCT
easat-4310	93	1	table	table	NOUN
easat-4310	93	2	3	3	NUM
easat-4310	93	3	presents	present	VERB
easat-4310	93	4	citrulline	citrulline	NOUN
easat-4310	93	5	dynamics	dynamic	NOUN
easat-4310	93	6	stratified	stratify	VERB
easat-4310	93	7	by	by	ADP
easat-4310	93	8	mucositis	mucositis	PROPN
easat-4310	93	9	severity	severity	NOUN
easat-4310	93	10	,	,	PUNCT
easat-4310	93	11	with	with	ADP
easat-4310	93	12	significant	significant	ADJ
easat-4310	93	13	changes	change	NOUN
easat-4310	93	14	observed	observe	VERB
easat-4310	93	15	in	in	ADP
easat-4310	93	16	patients	patient	NOUN
easat-4310	93	17	with	with	ADP
easat-4310	93	18	grade	grade	NOUN
easat-4310	93	19	1	1	NUM
easat-4310	93	20	mucositis	mucositis	NOUN
easat-4310	93	21	.	.	PUNCT
easat-4310	93	22	table	table	NOUN
easat-4310	94	1	3	3	NUM
easat-4310	94	2	.	.	PUNCT
easat-4310	94	3	citrulline	citrulline	NOUN
easat-4310	94	4	levels	level	NOUN
easat-4310	94	5	by	by	ADP
easat-4310	94	6	mucositis	mucositis	NOUN
easat-4310	94	7	severity	severity	NOUN
easat-4310	94	8	mucositis	mucositis	NOUN
easat-4310	94	9	severity	severity	NOUN
easat-4310	94	10	pre	pre	ADJ
easat-4310	94	11	-	-	ADJ
easat-4310	94	12	treatment	treatment	ADJ
easat-4310	94	13	citrulline	citrulline	NOUN
easat-4310	94	14	(	(	PUNCT
easat-4310	94	15	nmol	nmol	NOUN
easat-4310	94	16	/	/	SYM
easat-4310	94	17	l	l	NOUN
easat-4310	94	18	)	)	PUNCT
easat-4310	94	19	post	post	ADJ
easat-4310	94	20	-	-	ADJ
easat-4310	94	21	treatment	treatment	ADJ
easat-4310	94	22	citrulline	citrulline	NOUN
easat-4310	94	23	(	(	PUNCT
easat-4310	94	24	nmol	nmol	NOUN
easat-4310	94	25	/	/	SYM
easat-4310	94	26	l	l	NOUN
easat-4310	94	27	)	)	PUNCT
easat-4310	94	28	p	p	X
easat-4310	94	29	-	-	PUNCT
easat-4310	94	30	value	value	NOUN
easat-4310	94	31	normal	normal	ADJ
easat-4310	94	32	3.32	3.32	NUM
easat-4310	94	33	(	(	PUNCT
easat-4310	94	34	1.23	1.23	NUM
easat-4310	94	35	-	-	SYM
easat-4310	94	36	5.70	5.70	NUM
easat-4310	94	37	)	)	PUNCT
easat-4310	94	38	2.68	2.68	NUM
easat-4310	94	39	(	(	PUNCT
easat-4310	94	40	0.07	0.07	NUM
easat-4310	94	41	-	-	SYM
easat-4310	94	42	3.24	3.24	NUM
easat-4310	94	43	)	)	PUNCT
easat-4310	94	44	0.115	0.115	NUM
easat-4310	94	45	grade	grade	NOUN
easat-4310	94	46	1	1	NUM
easat-4310	94	47	3.82	3.82	NUM
easat-4310	94	48	(	(	PUNCT
easat-4310	94	49	1.06	1.06	NUM
easat-4310	94	50	-	-	SYM
easat-4310	94	51	5.84	5.84	NUM
easat-4310	94	52	)	)	PUNCT
easat-4310	94	53	3.95	3.95	NUM
easat-4310	94	54	(	(	PUNCT
easat-4310	94	55	1.14	1.14	NUM
easat-4310	94	56	-	-	SYM
easat-4310	94	57	12.99	12.99	NUM
easat-4310	94	58	)	)	PUNCT
easat-4310	94	59	0.036	0.036	NUM
easat-4310	94	60	*	*	PUNCT
easat-4310	94	61	grade	grade	NOUN
easat-4310	94	62	2	2	NUM
easat-4310	94	63	3.35	3.35	NUM
easat-4310	94	64	(	(	PUNCT
easat-4310	94	65	0.07	0.07	NUM
easat-4310	94	66	-	-	SYM
easat-4310	94	67	5.53	5.53	NUM
easat-4310	94	68	)	)	PUNCT
easat-4310	94	69	3.17	3.17	NUM
easat-4310	94	70	(	(	PUNCT
easat-4310	94	71	0.29	0.29	NUM
easat-4310	94	72	-	-	SYM
easat-4310	94	73	6.82	6.82	NUM
easat-4310	94	74	)	)	PUNCT
easat-4310	94	75	0.616	0.616	NUM
easat-4310	94	76	note	note	NOUN
easat-4310	94	77	:	:	PUNCT
easat-4310	94	78	*	*	PUNCT
easat-4310	94	79	statistically	statistically	ADV
easat-4310	94	80	significant	significant	ADJ
easat-4310	94	81	,	,	PUNCT
easat-4310	94	82	with	with	ADP
easat-4310	94	83	p	p	NOUN
easat-4310	94	84	-	-	PUNCT
easat-4310	94	85	value	value	NOUN
easat-4310	94	86	<	<	X
easat-4310	94	87	0.05	0.05	NUM
easat-4310	94	88	.	.	PUNCT
easat-4310	94	89	3.2	3.2	NUM
easat-4310	94	90	.	.	PUNCT
easat-4310	95	1	risk	risk	NOUN
easat-4310	95	2	stratification	stratification	NOUN
easat-4310	95	3	trends	trend	VERB
easat-4310	95	4	the	the	DET
easat-4310	95	5	divergence	divergence	NOUN
easat-4310	95	6	in	in	ADP
easat-4310	95	7	citrulline	citrulline	NOUN
easat-4310	95	8	levels	level	NOUN
easat-4310	95	9	between	between	ADP
easat-4310	95	10	sr	sr	PROPN
easat-4310	95	11	and	and	CCONJ
easat-4310	95	12	hr	hr	NOUN
easat-4310	95	13	groups	group	NOUN
easat-4310	95	14	highlights	highlight	VERB
easat-4310	95	15	potential	potential	ADJ
easat-4310	95	16	physiological	physiological	ADJ
easat-4310	95	17	differences	difference	NOUN
easat-4310	95	18	.	.	PUNCT
easat-4310	96	1	sr	sr	PROPN
easat-4310	96	2	patients	patient	NOUN
easat-4310	96	3	demonstrated	demonstrate	VERB
easat-4310	96	4	a	a	DET
easat-4310	96	5	predictable	predictable	ADJ
easat-4310	96	6	decline	decline	NOUN
easat-4310	96	7	in	in	ADP
easat-4310	96	8	citrulline	citrulline	NOUN
easat-4310	96	9	,	,	PUNCT
easat-4310	96	10	consistent	consistent	ADJ
easat-4310	96	11	with	with	ADP
easat-4310	96	12	mucositis	mucositis	PROPN
easat-4310	96	13	pathophysiology	pathophysiology	NOUN
easat-4310	96	14	.	.	PUNCT
easat-4310	97	1	the	the	DET
easat-4310	97	2	significant	significant	ADJ
easat-4310	97	3	increase	increase	NOUN
easat-4310	97	4	in	in	ADP
easat-4310	97	5	the	the	DET
easat-4310	97	6	hr	hr	NOUN
easat-4310	97	7	group	group	NOUN
easat-4310	97	8	suggests	suggest	VERB
easat-4310	97	9	enhanced	enhanced	ADJ
easat-4310	97	10	resilience	resilience	NOUN
easat-4310	97	11	or	or	CCONJ
easat-4310	97	12	a	a	DET
easat-4310	97	13	delayed	delay	VERB
easat-4310	97	14	response	response	NOUN
easat-4310	97	15	to	to	ADP
easat-4310	97	16	mucosal	mucosal	NOUN
easat-4310	97	17	injury	injury	NOUN
easat-4310	97	18	,	,	PUNCT
easat-4310	97	19	warranting	warrant	VERB
easat-4310	97	20	further	further	ADJ
easat-4310	97	21	investigation	investigation	NOUN
easat-4310	97	22	into	into	ADP
easat-4310	97	23	the	the	DET
easat-4310	97	24	underlying	underlie	VERB
easat-4310	97	25	mechanisms	mechanism	NOUN
easat-4310	97	26	.	.	PUNCT
easat-4310	98	1	4	4	X
easat-4310	98	2	.	.	X
easat-4310	98	3	discussion	discussion	NOUN
easat-4310	98	4	this	this	DET
easat-4310	98	5	study	study	NOUN
easat-4310	98	6	provides	provide	VERB
easat-4310	98	7	a	a	DET
easat-4310	98	8	detailed	detailed	ADJ
easat-4310	98	9	examination	examination	NOUN
easat-4310	98	10	of	of	ADP
easat-4310	98	11	citrulline	citrulline	NOUN
easat-4310	98	12	as	as	ADP
easat-4310	98	13	a	a	DET
easat-4310	98	14	biomarker	biomarker	NOUN
easat-4310	98	15	for	for	ADP
easat-4310	98	16	gastrointestinal	gastrointestinal	ADJ
easat-4310	98	17	mucositis	mucositis	NOUN
easat-4310	98	18	in	in	ADP
easat-4310	98	19	pediatric	pediatric	ADJ
easat-4310	98	20	patients	patient	NOUN
easat-4310	98	21	undergoing	undergo	VERB
easat-4310	98	22	high	high	ADJ
easat-4310	98	23	-	-	PUNCT
easat-4310	98	24	dose	dose	NOUN
easat-4310	98	25	methotrexate	methotrexate	NOUN
easat-4310	98	26	chemotherapy	chemotherapy	NOUN
easat-4310	98	27	.	.	PUNCT
easat-4310	99	1	the	the	DET
easat-4310	99	2	findings	finding	NOUN
easat-4310	99	3	underscore	underscore	VERB
easat-4310	99	4	the	the	DET
easat-4310	99	5	intricate	intricate	ADJ
easat-4310	99	6	relationship	relationship	NOUN
easat-4310	99	7	between	between	ADP
easat-4310	99	8	mucosal	mucosal	NOUN
easat-4310	99	9	injury	injury	NOUN
easat-4310	99	10	,	,	PUNCT
easat-4310	99	11	recovery	recovery	NOUN
easat-4310	99	12	processes	process	NOUN
easat-4310	99	13	,	,	PUNCT
easat-4310	99	14	and	and	CCONJ
easat-4310	99	15	individual	individual	ADJ
easat-4310	99	16	patient	patient	NOUN
easat-4310	99	17	characteristics	characteristic	NOUN
easat-4310	99	18	.	.	PUNCT
easat-4310	100	1	citrulline	citrulline	NOUN
easat-4310	100	2	,	,	PUNCT
easat-4310	100	3	synthesized	synthesize	VERB
easat-4310	100	4	predominantly	predominantly	ADV
easat-4310	100	5	by	by	ADP
easat-4310	100	6	enterocytes	enterocyte	NOUN
easat-4310	100	7	,	,	PUNCT
easat-4310	100	8	serves	serve	VERB
easat-4310	100	9	as	as	ADP
easat-4310	100	10	an	an	DET
easat-4310	100	11	essential	essential	ADJ
easat-4310	100	12	indicator	indicator	NOUN
easat-4310	100	13	of	of	ADP
easat-4310	100	14	intestinal	intestinal	ADJ
easat-4310	100	15	epithelial	epithelial	ADJ
easat-4310	100	16	integrity	integrity	NOUN
easat-4310	100	17	,	,	PUNCT
easat-4310	100	18	with	with	ADP
easat-4310	100	19	its	its	PRON
easat-4310	100	20	serum	serum	NOUN
easat-4310	100	21	levels	level	NOUN
easat-4310	100	22	directly	directly	ADV
easat-4310	100	23	reflecting	reflect	VERB
easat-4310	100	24	functional	functional	ADJ
easat-4310	100	25	enterocyte	enterocyte	NOUN
easat-4310	100	26	mass	mass	PROPN
easat-4310	101	1	[	[	X
easat-4310	101	2	12	12	NUM
easat-4310	101	3	]	]	PUNCT
easat-4310	101	4	.	.	PUNCT
easat-4310	102	1	its	its	PRON
easat-4310	102	2	serum	serum	NOUN
easat-4310	102	3	levels	level	NOUN
easat-4310	102	4	are	be	AUX
easat-4310	102	5	directly	directly	ADV
easat-4310	102	6	proportional	proportional	ADJ
easat-4310	102	7	to	to	ADP
easat-4310	102	8	functional	functional	ADJ
easat-4310	102	9	enterocyte	enterocyte	NOUN
easat-4310	102	10	mass	mass	PROPN
easat-4310	102	11	,	,	PUNCT
easat-4310	102	12	making	make	VERB
easat-4310	102	13	it	it	PRON
easat-4310	102	14	an	an	DET
easat-4310	102	15	invaluable	invaluable	ADJ
easat-4310	102	16	tool	tool	NOUN
easat-4310	102	17	for	for	ADP
easat-4310	102	18	assessing	assess	VERB
easat-4310	102	19	mucosal	mucosal	ADJ
easat-4310	102	20	health	health	NOUN
easat-4310	103	1	[	[	X
easat-4310	103	2	11	11	NUM
easat-4310	103	3	]	]	PUNCT
easat-4310	103	4	.	.	PUNCT
easat-4310	104	1	in	in	ADP
easat-4310	104	2	standard	standard	ADJ
easat-4310	104	3	risk	risk	NOUN
easat-4310	104	4	patients	patient	NOUN
easat-4310	104	5	,	,	PUNCT
easat-4310	104	6	the	the	DET
easat-4310	104	7	observed	observed	ADJ
easat-4310	104	8	decline	decline	NOUN
easat-4310	104	9	in	in	ADP
easat-4310	104	10	citrulline	citrulline	NOUN
easat-4310	104	11	levels	level	NOUN
easat-4310	104	12	following	follow	VERB
easat-4310	104	13	chemotherapy	chemotherapy	NOUN
easat-4310	104	14	aligns	align	VERB
easat-4310	104	15	with	with	ADP
easat-4310	104	16	established	establish	VERB
easat-4310	104	17	pathophysiological	pathophysiological	ADJ
easat-4310	104	18	mechanisms	mechanism	NOUN
easat-4310	104	19	of	of	ADP
easat-4310	104	20	mucosal	mucosal	NOUN
easat-4310	104	21	damage	damage	NOUN
easat-4310	104	22	.	.	PUNCT
easat-4310	105	1	methotrexate	methotrexate	NOUN
easat-4310	105	2	,	,	PUNCT
easat-4310	105	3	a	a	DET
easat-4310	105	4	cytotoxic	cytotoxic	ADJ
easat-4310	105	5	agent	agent	NOUN
easat-4310	105	6	targeting	target	VERB
easat-4310	105	7	rapidly	rapidly	ADV
easat-4310	105	8	dividing	divide	VERB
easat-4310	105	9	cells	cell	NOUN
easat-4310	105	10	,	,	PUNCT
easat-4310	105	11	causes	cause	VERB
easat-4310	105	12	significant	significant	ADJ
easat-4310	105	13	epithelial	epithelial	ADJ
easat-4310	105	14	disruption	disruption	NOUN
easat-4310	105	15	,	,	PUNCT
easat-4310	105	16	leading	lead	VERB
easat-4310	105	17	to	to	ADP
easat-4310	105	18	enterocyte	enterocyte	NOUN
easat-4310	105	19	loss	loss	NOUN
easat-4310	105	20	and	and	CCONJ
easat-4310	105	21	reduced	reduce	VERB
easat-4310	105	22	citrulline	citrulline	NOUN
easat-4310	105	23	synthesis	synthesis	NOUN
easat-4310	105	24	[	[	X
easat-4310	105	25	16	16	NUM
easat-4310	105	26	]	]	PUNCT
easat-4310	105	27	.	.	PUNCT
easat-4310	106	1	this	this	DET
easat-4310	106	2	consistent	consistent	ADJ
easat-4310	106	3	trend	trend	NOUN
easat-4310	106	4	with	with	ADP
easat-4310	106	5	prior	prior	ADJ
easat-4310	106	6	studies	study	NOUN
easat-4310	106	7	reinforces	reinforce	VERB
easat-4310	106	8	citrulline	citrulline	NOUN
easat-4310	106	9	's	's	PART
easat-4310	106	10	sensitivity	sensitivity	NOUN
easat-4310	106	11	and	and	CCONJ
easat-4310	106	12	specificity	specificity	NOUN
easat-4310	106	13	as	as	ADP
easat-4310	106	14	a	a	DET
easat-4310	106	15	biomarker	biomarker	NOUN
easat-4310	106	16	for	for	ADP
easat-4310	106	17	chemotherapy	chemotherapy	NOUN
easat-4310	106	18	-	-	ADJ
easat-4310	106	19	induced	induce	VERB
easat-4310	106	20	intestinal	intestinal	ADJ
easat-4310	106	21	injury	injury	NOUN
easat-4310	106	22	[	[	X
easat-4310	106	23	17	17	NUM
easat-4310	106	24	]	]	PUNCT
easat-4310	106	25	.	.	PUNCT
easat-4310	107	1	beyond	beyond	ADP
easat-4310	107	2	its	its	PRON
easat-4310	107	3	diagnostic	diagnostic	ADJ
easat-4310	107	4	utility	utility	NOUN
easat-4310	107	5	,	,	PUNCT
easat-4310	107	6	citrulline	citrulline	NOUN
easat-4310	107	7	level	level	NOUN
easat-4310	107	8	role	role	NOUN
easat-4310	107	9	extends	extend	VERB
easat-4310	107	10	to	to	ADP
easat-4310	107	11	providing	provide	VERB
easat-4310	107	12	insights	insight	NOUN
easat-4310	107	13	into	into	ADP
easat-4310	107	14	the	the	DET
easat-4310	107	15	dynamic	dynamic	ADJ
easat-4310	107	16	process	process	NOUN
easat-4310	107	17	of	of	ADP
easat-4310	107	18	mucosal	mucosal	ADJ
easat-4310	107	19	damage	damage	NOUN
easat-4310	107	20	and	and	CCONJ
easat-4310	107	21	regeneration	regeneration	NOUN
easat-4310	107	22	.	.	PUNCT
easat-4310	108	1	a	a	DET
easat-4310	108	2	decline	decline	NOUN
easat-4310	108	3	in	in	ADP
easat-4310	108	4	levels	level	NOUN
easat-4310	108	5	not	not	PART
easat-4310	108	6	only	only	ADV
easat-4310	108	7	signals	signal	VERB
easat-4310	108	8	acute	acute	ADJ
easat-4310	108	9	injury	injury	NOUN
easat-4310	108	10	but	but	CCONJ
easat-4310	108	11	also	also	ADV
easat-4310	108	12	reflects	reflect	VERB
easat-4310	108	13	the	the	DET
easat-4310	108	14	degree	degree	NOUN
easat-4310	108	15	of	of	ADP
easat-4310	108	16	epithelial	epithelial	ADJ
easat-4310	108	17	compromise	compromise	NOUN
easat-4310	108	18	,	,	PUNCT
easat-4310	108	19	which	which	PRON
easat-4310	108	20	can	can	AUX
easat-4310	108	21	influence	influence	VERB
easat-4310	108	22	clinical	clinical	ADJ
easat-4310	108	23	decision	decision	NOUN
easat-4310	108	24	-	-	PUNCT
easat-4310	108	25	making	making	NOUN
easat-4310	108	26	[	[	X
easat-4310	108	27	18	18	NUM
easat-4310	108	28	]	]	PUNCT
easat-4310	108	29	.	.	PUNCT
easat-4310	109	1	however	however	ADV
easat-4310	109	2	,	,	PUNCT
easat-4310	109	3	its	its	PRON
easat-4310	109	4	sensitivity	sensitivity	NOUN
easat-4310	109	5	to	to	ADP
easat-4310	109	6	other	other	ADJ
easat-4310	109	7	systemic	systemic	ADJ
easat-4310	109	8	factors	factor	NOUN
easat-4310	109	9	,	,	PUNCT
easat-4310	109	10	such	such	ADJ
easat-4310	109	11	as	as	ADP
easat-4310	109	12	inflammation	inflammation	NOUN
easat-4310	109	13	and	and	CCONJ
easat-4310	109	14	metabolic	metabolic	NOUN
easat-4310	109	15	variations	variation	NOUN
easat-4310	109	16	,	,	PUNCT
easat-4310	109	17	necessitates	necessitate	VERB
easat-4310	109	18	cautious	cautious	ADJ
easat-4310	109	19	interpretation	interpretation	NOUN
easat-4310	109	20	[	[	X
easat-4310	109	21	19	19	NUM
easat-4310	109	22	]	]	PUNCT
easat-4310	109	23	.	.	PUNCT
easat-4310	110	1	despite	despite	SCONJ
easat-4310	110	2	these	these	DET
easat-4310	110	3	complexities	complexity	NOUN
easat-4310	110	4	,	,	PUNCT
easat-4310	110	5	citrulline	citrulline	NOUN
easat-4310	110	6	is	be	AUX
easat-4310	110	7	non	non	ADJ
easat-4310	110	8	-	-	ADJ
easat-4310	110	9	invasive	invasive	ADJ
easat-4310	110	10	procedure	procedure	NOUN
easat-4310	110	11	and	and	CCONJ
easat-4310	110	12	proven	prove	VERB
easat-4310	110	13	correlation	correlation	NOUN
easat-4310	110	14	with	with	ADP
easat-4310	110	15	mucosal	mucosal	NOUN
easat-4310	110	16	integrity	integrity	NOUN
easat-4310	110	17	make	make	VERB
easat-4310	110	18	it	it	PRON
easat-4310	110	19	an	an	DET
easat-4310	110	20	indispensable	indispensable	ADJ
easat-4310	110	21	marker	marker	NOUN
easat-4310	110	22	in	in	ADP
easat-4310	110	23	pediatric	pediatric	ADJ
easat-4310	110	24	oncology	oncology	NOUN
easat-4310	110	25	,	,	PUNCT
easat-4310	110	26	particularly	particularly	ADV
easat-4310	110	27	for	for	ADP
easat-4310	110	28	monitoring	monitor	VERB
easat-4310	110	29	gastrointestinal	gastrointestinal	ADJ
easat-4310	110	30	toxicity	toxicity	NOUN
easat-4310	110	31	and	and	CCONJ
easat-4310	110	32	guiding	guide	VERB
easat-4310	110	33	timely	timely	ADJ
easat-4310	110	34	interventions	intervention	NOUN
easat-4310	110	35	.	.	PUNCT
easat-4310	111	1	this	this	PRON
easat-4310	111	2	highlights	highlight	VERB
easat-4310	111	3	its	its	PRON
easat-4310	111	4	potential	potential	NOUN
easat-4310	111	5	to	to	PART
easat-4310	111	6	improve	improve	VERB
easat-4310	111	7	outcomes	outcome	NOUN
easat-4310	111	8	through	through	ADP
easat-4310	111	9	more	more	ADV
easat-4310	111	10	personalized	personalized	ADJ
easat-4310	111	11	,	,	PUNCT
easat-4310	111	12	biomarker	biomarker	NOUN
easat-4310	111	13	-	-	PUNCT
easat-4310	111	14	driven	drive	VERB
easat-4310	111	15	care	care	NOUN
easat-4310	111	16	strategies	strategy	NOUN
easat-4310	111	17	[	[	X
easat-4310	111	18	20	20	NUM
easat-4310	111	19	]	]	PUNCT
easat-4310	111	20	.	.	PUNCT
easat-4310	112	1	in	in	ADP
easat-4310	112	2	contrast	contrast	NOUN
easat-4310	112	3	to	to	ADP
easat-4310	112	4	the	the	DET
easat-4310	112	5	standard	standard	ADJ
easat-4310	112	6	risk	risk	NOUN
easat-4310	112	7	group	group	NOUN
easat-4310	112	8	,	,	PUNCT
easat-4310	112	9	the	the	DET
easat-4310	112	10	high	high	ADJ
easat-4310	112	11	-	-	PUNCT
easat-4310	112	12	risk	risk	NOUN
easat-4310	112	13	group	group	NOUN
easat-4310	112	14	exhibited	exhibit	VERB
easat-4310	112	15	an	an	DET
easat-4310	112	16	unexpected	unexpected	ADJ
easat-4310	112	17	increase	increase	NOUN
easat-4310	112	18	in	in	ADP
easat-4310	112	19	serum	serum	NOUN
easat-4310	112	20	citrulline	citrulline	NOUN
easat-4310	112	21	levels	level	NOUN
easat-4310	112	22	post	post	NOUN
easat-4310	112	23	-	-	NOUN
easat-4310	112	24	chemotherapy	chemotherapy	NOUN
easat-4310	112	25	.	.	PUNCT
easat-4310	113	1	this	this	DET
easat-4310	113	2	deviation	deviation	NOUN
easat-4310	113	3	from	from	ADP
easat-4310	113	4	the	the	DET
easat-4310	113	5	anticipated	anticipate	VERB
easat-4310	113	6	pattern	pattern	NOUN
easat-4310	113	7	of	of	ADP
easat-4310	113	8	citrulline	citrulline	NOUN
easat-4310	113	9	reduction	reduction	NOUN
easat-4310	113	10	warrants	warrant	NOUN
easat-4310	113	11	critical	critical	ADJ
easat-4310	113	12	evaluation	evaluation	NOUN
easat-4310	113	13	,	,	PUNCT
easat-4310	113	14	as	as	SCONJ
easat-4310	113	15	it	it	PRON
easat-4310	113	16	suggests	suggest	VERB
easat-4310	113	17	the	the	DET
easat-4310	113	18	presence	presence	NOUN
easat-4310	113	19	of	of	ADP
easat-4310	113	20	unique	unique	ADJ
easat-4310	113	21	physiological	physiological	ADJ
easat-4310	113	22	responses	response	NOUN
easat-4310	113	23	or	or	CCONJ
easat-4310	113	24	external	external	ADJ
easat-4310	113	25	influences	influence	NOUN
easat-4310	113	26	that	that	PRON
easat-4310	113	27	may	may	AUX
easat-4310	113	28	modulate	modulate	VERB
easat-4310	113	29	citrulline	citrulline	NOUN
easat-4310	113	30	dynamics	dynamic	NOUN
easat-4310	113	31	in	in	ADP
easat-4310	113	32	this	this	DET
easat-4310	113	33	subgroup	subgroup	NOUN
easat-4310	113	34	[	[	X
easat-4310	113	35	21	21	NUM
easat-4310	113	36	]	]	PUNCT
easat-4310	113	37	.	.	PUNCT
easat-4310	114	1	1082	1082	NUM
easat-4310	114	2	edelweiss	edelweiss	PROPN
easat-4310	114	3	applied	apply	VERB
easat-4310	114	4	science	science	NOUN
easat-4310	114	5	and	and	CCONJ
easat-4310	114	6	technology	technology	NOUN
easat-4310	114	7	issn	issn	PROPN
easat-4310	114	8	:	:	PUNCT
easat-4310	114	9	2576	2576	NUM
easat-4310	114	10	-	-	SYM
easat-4310	114	11	8484	8484	NUM
easat-4310	114	12	vol	vol	NOUN
easat-4310	114	13	.	.	PROPN
easat-4310	115	1	9	9	NUM
easat-4310	115	2	,	,	PUNCT
easat-4310	115	3	no	no	INTJ
easat-4310	115	4	.	.	NOUN
easat-4310	115	5	1	1	NUM
easat-4310	115	6	:	:	SYM
easat-4310	115	7	1078	1078	NUM
easat-4310	115	8	-	-	SYM
easat-4310	115	9	1085	1085	NUM
easat-4310	115	10	,	,	PUNCT
easat-4310	115	11	2025	2025	NUM
easat-4310	115	12	doi	doi	NOUN
easat-4310	115	13	:	:	PUNCT
easat-4310	115	14	10.55214/25768484.v9i1.4310	10.55214/25768484.v9i1.4310	NUM
easat-4310	115	15	©	©	PROPN
easat-4310	115	16	2025	2025	NUM
easat-4310	115	17	by	by	ADP
easat-4310	115	18	the	the	DET
easat-4310	115	19	authors	author	NOUN
easat-4310	115	20	;	;	PUNCT
easat-4310	115	21	licensee	licensee	PROPN
easat-4310	115	22	learning	learn	VERB
easat-4310	115	23	gate	gate	NOUN
easat-4310	115	24	understanding	understand	VERB
easat-4310	115	25	these	these	DET
easat-4310	115	26	deviations	deviation	NOUN
easat-4310	115	27	is	be	AUX
easat-4310	115	28	essential	essential	ADJ
easat-4310	115	29	to	to	ADP
easat-4310	115	30	optimizing	optimize	VERB
easat-4310	115	31	the	the	DET
easat-4310	115	32	biomarker	biomarker	NOUN
easat-4310	115	33	’s	’s	PART
easat-4310	115	34	utility	utility	NOUN
easat-4310	115	35	in	in	ADP
easat-4310	115	36	clinical	clinical	ADJ
easat-4310	115	37	practice	practice	NOUN
easat-4310	115	38	,	,	PUNCT
easat-4310	115	39	particularly	particularly	ADV
easat-4310	115	40	in	in	ADP
easat-4310	115	41	the	the	DET
easat-4310	115	42	context	context	NOUN
easat-4310	115	43	of	of	ADP
easat-4310	115	44	high	high	ADJ
easat-4310	115	45	-	-	PUNCT
easat-4310	115	46	dose	dose	NOUN
easat-4310	115	47	methotrexate	methotrexate	NOUN
easat-4310	115	48	(	(	PUNCT
easat-4310	115	49	hd	hd	NOUN
easat-4310	115	50	-	-	PUNCT
easat-4310	115	51	mtx	mtx	NOUN
easat-4310	115	52	)	)	PUNCT
easat-4310	115	53	therapy	therapy	NOUN
easat-4310	115	54	.	.	PUNCT
easat-4310	116	1	a	a	DET
easat-4310	116	2	plausible	plausible	ADJ
easat-4310	116	3	explanation	explanation	NOUN
easat-4310	116	4	for	for	ADP
easat-4310	116	5	this	this	DET
easat-4310	116	6	finding	finding	NOUN
easat-4310	116	7	lies	lie	VERB
easat-4310	116	8	in	in	ADP
easat-4310	116	9	the	the	DET
easat-4310	116	10	activation	activation	NOUN
easat-4310	116	11	of	of	ADP
easat-4310	116	12	compensatory	compensatory	ADJ
easat-4310	116	13	mechanisms	mechanism	NOUN
easat-4310	116	14	aimed	aim	VERB
easat-4310	116	15	at	at	ADP
easat-4310	116	16	preserving	preserve	VERB
easat-4310	116	17	intestinal	intestinal	ADJ
easat-4310	116	18	integrity	integrity	NOUN
easat-4310	116	19	.	.	PUNCT
easat-4310	117	1	chemotherapy	chemotherapy	NOUN
easat-4310	117	2	-	-	ADJ
easat-4310	117	3	induced	induce	VERB
easat-4310	117	4	mucosal	mucosal	NOUN
easat-4310	117	5	injury	injury	NOUN
easat-4310	117	6	typically	typically	ADV
easat-4310	117	7	triggers	trigger	VERB
easat-4310	117	8	a	a	DET
easat-4310	117	9	cascade	cascade	NOUN
easat-4310	117	10	of	of	ADP
easat-4310	117	11	biological	biological	ADJ
easat-4310	117	12	responses	response	NOUN
easat-4310	117	13	,	,	PUNCT
easat-4310	117	14	including	include	VERB
easat-4310	117	15	enterocyte	enterocyte	NOUN
easat-4310	117	16	proliferation	proliferation	NOUN
easat-4310	117	17	and	and	CCONJ
easat-4310	117	18	epithelial	epithelial	ADJ
easat-4310	117	19	regeneration	regeneration	NOUN
easat-4310	117	20	.	.	PUNCT
easat-4310	118	1	in	in	ADP
easat-4310	118	2	high	high	ADJ
easat-4310	118	3	-	-	PUNCT
easat-4310	118	4	risk	risk	NOUN
easat-4310	118	5	patients	patient	NOUN
easat-4310	118	6	,	,	PUNCT
easat-4310	118	7	who	who	PRON
easat-4310	118	8	often	often	ADV
easat-4310	118	9	present	present	VERB
easat-4310	118	10	with	with	ADP
easat-4310	118	11	more	more	ADV
easat-4310	118	12	aggressive	aggressive	ADJ
easat-4310	118	13	disease	disease	NOUN
easat-4310	118	14	phenotypes	phenotype	NOUN
easat-4310	118	15	and	and	CCONJ
easat-4310	118	16	undergo	undergo	VERB
easat-4310	118	17	more	more	ADV
easat-4310	118	18	intensive	intensive	ADJ
easat-4310	118	19	treatment	treatment	NOUN
easat-4310	118	20	regimens	regimen	NOUN
easat-4310	118	21	,	,	PUNCT
easat-4310	118	22	the	the	DET
easat-4310	118	23	adaptive	adaptive	ADJ
easat-4310	118	24	response	response	NOUN
easat-4310	118	25	may	may	AUX
easat-4310	118	26	be	be	AUX
easat-4310	118	27	heightened	heighten	VERB
easat-4310	118	28	.	.	PUNCT
easat-4310	119	1	enhanced	enhance	VERB
easat-4310	119	2	enterocyte	enterocyte	NOUN
easat-4310	119	3	proliferation	proliferation	NOUN
easat-4310	119	4	could	could	AUX
easat-4310	119	5	result	result	VERB
easat-4310	119	6	in	in	ADP
easat-4310	119	7	increased	increase	VERB
easat-4310	119	8	citrulline	citrulline	NOUN
easat-4310	119	9	synthesis	synthesis	NOUN
easat-4310	119	10	,	,	PUNCT
easat-4310	119	11	counteracting	counteract	VERB
easat-4310	119	12	the	the	DET
easat-4310	119	13	expected	expect	VERB
easat-4310	119	14	decline	decline	NOUN
easat-4310	119	15	associated	associate	VERB
easat-4310	119	16	with	with	ADP
easat-4310	119	17	mucosal	mucosal	NOUN
easat-4310	119	18	injury	injury	NOUN
easat-4310	120	1	[	[	X
easat-4310	120	2	16	16	NUM
easat-4310	120	3	]	]	PUNCT
easat-4310	120	4	.	.	PUNCT
easat-4310	121	1	this	this	DET
easat-4310	121	2	phenomenon	phenomenon	NOUN
easat-4310	121	3	underscores	underscore	VERB
easat-4310	121	4	the	the	DET
easat-4310	121	5	complexity	complexity	NOUN
easat-4310	121	6	of	of	ADP
easat-4310	121	7	citrulline	citrulline	NOUN
easat-4310	121	8	as	as	ADP
easat-4310	121	9	a	a	DET
easat-4310	121	10	biomarker	biomarker	NOUN
easat-4310	121	11	,	,	PUNCT
easat-4310	121	12	as	as	SCONJ
easat-4310	121	13	its	its	PRON
easat-4310	121	14	levels	level	NOUN
easat-4310	121	15	may	may	AUX
easat-4310	121	16	reflect	reflect	VERB
easat-4310	121	17	not	not	PART
easat-4310	121	18	only	only	ADV
easat-4310	121	19	enterocyte	enterocyte	NOUN
easat-4310	121	20	mass	mass	PROPN
easat-4310	121	21	but	but	CCONJ
easat-4310	121	22	also	also	ADV
easat-4310	121	23	the	the	DET
easat-4310	121	24	dynamic	dynamic	ADJ
easat-4310	121	25	balance	balance	NOUN
easat-4310	121	26	between	between	ADP
easat-4310	121	27	injury	injury	NOUN
easat-4310	121	28	and	and	CCONJ
easat-4310	121	29	repair	repair	NOUN
easat-4310	121	30	processes	process	NOUN
easat-4310	121	31	.	.	PUNCT
easat-4310	122	1	another	another	DET
easat-4310	122	2	critical	critical	ADJ
easat-4310	122	3	factor	factor	NOUN
easat-4310	122	4	influencing	influence	VERB
easat-4310	122	5	citrulline	citrulline	NOUN
easat-4310	122	6	dynamics	dynamic	NOUN
easat-4310	122	7	in	in	ADP
easat-4310	122	8	high	high	ADJ
easat-4310	122	9	-	-	PUNCT
easat-4310	122	10	risk	risk	NOUN
easat-4310	122	11	patients	patient	NOUN
easat-4310	122	12	is	be	AUX
easat-4310	122	13	systemic	systemic	ADJ
easat-4310	122	14	inflammation	inflammation	NOUN
easat-4310	122	15	.	.	PUNCT
easat-4310	123	1	chemotherapy	chemotherapy	NOUN
easat-4310	123	2	often	often	ADV
easat-4310	123	3	induces	induce	VERB
easat-4310	123	4	a	a	DET
easat-4310	123	5	heightened	heightened	ADJ
easat-4310	123	6	inflammatory	inflammatory	ADJ
easat-4310	123	7	response	response	NOUN
easat-4310	123	8	,	,	PUNCT
easat-4310	123	9	characterized	characterize	VERB
easat-4310	123	10	by	by	ADP
easat-4310	123	11	elevated	elevated	ADJ
easat-4310	123	12	levels	level	NOUN
easat-4310	123	13	of	of	ADP
easat-4310	123	14	pro	pro	ADJ
easat-4310	123	15	-	-	ADJ
easat-4310	123	16	inflammatory	inflammatory	ADJ
easat-4310	123	17	cytokines	cytokine	NOUN
easat-4310	123	18	such	such	ADJ
easat-4310	123	19	as	as	ADP
easat-4310	123	20	tumor	tumor	NOUN
easat-4310	123	21	necrosis	necrosis	NOUN
easat-4310	123	22	factor	factor	NOUN
easat-4310	123	23	-	-	PUNCT
easat-4310	123	24	alpha	alpha	NOUN
easat-4310	123	25	(	(	PUNCT
easat-4310	123	26	tnf	tnf	PROPN
easat-4310	123	27	-	-	PUNCT
easat-4310	123	28	α	α	NOUN
easat-4310	123	29	)	)	PUNCT
easat-4310	123	30	and	and	CCONJ
easat-4310	123	31	interleukins	interleukin	VERB
easat-4310	123	32	(	(	PUNCT
easat-4310	123	33	il-6	il-6	NOUN
easat-4310	123	34	and	and	CCONJ
easat-4310	123	35	il-1β	il-1β	PROPN
easat-4310	123	36	)	)	PUNCT
easat-4310	123	37	.	.	PUNCT
easat-4310	124	1	these	these	DET
easat-4310	124	2	cytokines	cytokine	NOUN
easat-4310	124	3	can	can	AUX
easat-4310	124	4	modulate	modulate	VERB
easat-4310	124	5	intestinal	intestinal	ADJ
easat-4310	124	6	permeability	permeability	NOUN
easat-4310	124	7	and	and	CCONJ
easat-4310	124	8	alter	alter	VERB
easat-4310	124	9	amino	amino	NOUN
easat-4310	124	10	acid	acid	PROPN
easat-4310	124	11	metabolism	metabolism	NOUN
easat-4310	124	12	,	,	PUNCT
easat-4310	124	13	potentially	potentially	ADV
easat-4310	124	14	leading	lead	VERB
easat-4310	124	15	to	to	ADP
easat-4310	124	16	increased	increase	VERB
easat-4310	124	17	citrulline	citrulline	NOUN
easat-4310	124	18	synthesis	synthesis	NOUN
easat-4310	124	19	or	or	CCONJ
easat-4310	124	20	reduced	reduce	VERB
easat-4310	124	21	clearance	clearance	NOUN
easat-4310	124	22	[	[	X
easat-4310	124	23	17	17	NUM
easat-4310	124	24	]	]	PUNCT
easat-4310	124	25	.	.	PUNCT
easat-4310	125	1	this	this	DET
easat-4310	125	2	interplay	interplay	NOUN
easat-4310	125	3	between	between	ADP
easat-4310	125	4	systemic	systemic	ADJ
easat-4310	125	5	inflammation	inflammation	NOUN
easat-4310	125	6	and	and	CCONJ
easat-4310	125	7	citrulline	citrulline	NOUN
easat-4310	125	8	dynamics	dynamic	NOUN
easat-4310	125	9	adds	add	VERB
easat-4310	125	10	another	another	DET
easat-4310	125	11	layer	layer	NOUN
easat-4310	125	12	of	of	ADP
easat-4310	125	13	complexity	complexity	NOUN
easat-4310	125	14	to	to	ADP
easat-4310	125	15	the	the	DET
easat-4310	125	16	interpretation	interpretation	NOUN
easat-4310	125	17	of	of	ADP
easat-4310	125	18	results	result	NOUN
easat-4310	125	19	in	in	ADP
easat-4310	125	20	this	this	DET
easat-4310	125	21	population	population	NOUN
easat-4310	125	22	.	.	PUNCT
easat-4310	126	1	in	in	ADP
easat-4310	126	2	addition	addition	NOUN
easat-4310	126	3	to	to	ADP
easat-4310	126	4	inflammation	inflammation	NOUN
easat-4310	126	5	and	and	CCONJ
easat-4310	126	6	compensatory	compensatory	ADJ
easat-4310	126	7	regeneration	regeneration	NOUN
easat-4310	126	8	,	,	PUNCT
easat-4310	126	9	genetic	genetic	ADJ
easat-4310	126	10	factors	factor	NOUN
easat-4310	126	11	may	may	AUX
easat-4310	126	12	also	also	ADV
easat-4310	126	13	play	play	VERB
easat-4310	126	14	a	a	DET
easat-4310	126	15	significant	significant	ADJ
easat-4310	126	16	role	role	NOUN
easat-4310	126	17	in	in	ADP
easat-4310	126	18	modulating	modulate	VERB
easat-4310	126	19	citrulline	citrulline	NOUN
easat-4310	126	20	levels	level	NOUN
easat-4310	126	21	in	in	ADP
easat-4310	126	22	high	high	ADJ
easat-4310	126	23	-	-	PUNCT
easat-4310	126	24	risk	risk	NOUN
easat-4310	126	25	patients	patient	NOUN
easat-4310	126	26	.	.	PUNCT
easat-4310	127	1	variations	variation	NOUN
easat-4310	127	2	in	in	ADP
easat-4310	127	3	genes	gene	NOUN
easat-4310	127	4	related	relate	VERB
easat-4310	127	5	to	to	ADP
easat-4310	127	6	amino	amino	NOUN
easat-4310	127	7	acid	acid	NOUN
easat-4310	127	8	metabolism	metabolism	NOUN
easat-4310	127	9	,	,	PUNCT
easat-4310	127	10	such	such	ADJ
easat-4310	127	11	as	as	ADP
easat-4310	127	12	those	those	PRON
easat-4310	127	13	encoding	encode	VERB
easat-4310	127	14	enzymes	enzyme	NOUN
easat-4310	127	15	involved	involve	VERB
easat-4310	127	16	in	in	ADP
easat-4310	127	17	the	the	DET
easat-4310	127	18	urea	urea	NOUN
easat-4310	127	19	cycle	cycle	NOUN
easat-4310	127	20	,	,	PUNCT
easat-4310	127	21	could	could	AUX
easat-4310	127	22	influence	influence	VERB
easat-4310	127	23	citrulline	citrulline	NOUN
easat-4310	127	24	synthesis	synthesis	NOUN
easat-4310	127	25	and	and	CCONJ
easat-4310	127	26	clearance	clearance	NOUN
easat-4310	127	27	.	.	PUNCT
easat-4310	128	1	for	for	ADP
easat-4310	128	2	instance	instance	NOUN
easat-4310	128	3	,	,	PUNCT
easat-4310	128	4	polymorphisms	polymorphism	NOUN
easat-4310	128	5	in	in	ADP
easat-4310	128	6	the	the	DET
easat-4310	128	7	ornithine	ornithine	NOUN
easat-4310	128	8	transcarbamylase	transcarbamylase	NOUN
easat-4310	128	9	(	(	PUNCT
easat-4310	128	10	otc	otc	PROPN
easat-4310	128	11	)	)	PUNCT
easat-4310	128	12	gene	gene	NOUN
easat-4310	128	13	or	or	CCONJ
easat-4310	128	14	argininosuccinate	argininosuccinate	NOUN
easat-4310	128	15	synthetase	synthetase	NOUN
easat-4310	128	16	(	(	PUNCT
easat-4310	128	17	ass1	ass1	PROPN
easat-4310	128	18	)	)	PUNCT
easat-4310	128	19	gene	gene	NOUN
easat-4310	128	20	may	may	AUX
easat-4310	128	21	affect	affect	VERB
easat-4310	128	22	the	the	DET
easat-4310	128	23	efficiency	efficiency	NOUN
easat-4310	128	24	of	of	ADP
easat-4310	128	25	citrulline	citrulline	NOUN
easat-4310	128	26	production	production	NOUN
easat-4310	128	27	in	in	ADP
easat-4310	128	28	enterocytes	enterocyte	NOUN
easat-4310	128	29	.	.	PUNCT
easat-4310	129	1	these	these	DET
easat-4310	129	2	genetic	genetic	ADJ
easat-4310	129	3	variations	variation	NOUN
easat-4310	129	4	,	,	PUNCT
easat-4310	129	5	which	which	PRON
easat-4310	129	6	may	may	AUX
easat-4310	129	7	have	have	VERB
easat-4310	129	8	distinct	distinct	ADJ
easat-4310	129	9	prevalence	prevalence	NOUN
easat-4310	129	10	rates	rate	NOUN
easat-4310	129	11	in	in	ADP
easat-4310	129	12	different	different	ADJ
easat-4310	129	13	populations	population	NOUN
easat-4310	129	14	,	,	PUNCT
easat-4310	129	15	could	could	AUX
easat-4310	129	16	partially	partially	ADV
easat-4310	129	17	explain	explain	VERB
easat-4310	129	18	the	the	DET
easat-4310	129	19	unique	unique	ADJ
easat-4310	129	20	citrulline	citrulline	NOUN
easat-4310	129	21	dynamics	dynamic	NOUN
easat-4310	129	22	observed	observe	VERB
easat-4310	129	23	in	in	ADP
easat-4310	129	24	this	this	DET
easat-4310	129	25	cohort	cohort	NOUN
easat-4310	130	1	[	[	X
easat-4310	130	2	22	22	NUM
easat-4310	130	3	]	]	PUNCT
easat-4310	130	4	.	.	PUNCT
easat-4310	131	1	nutritional	nutritional	ADJ
easat-4310	131	2	status	status	NOUN
easat-4310	131	3	is	be	AUX
easat-4310	131	4	another	another	DET
easat-4310	131	5	critical	critical	ADJ
easat-4310	131	6	variable	variable	NOUN
easat-4310	131	7	that	that	PRON
easat-4310	131	8	must	must	AUX
easat-4310	131	9	be	be	AUX
easat-4310	131	10	considered	consider	VERB
easat-4310	131	11	when	when	SCONJ
easat-4310	131	12	evaluating	evaluate	VERB
easat-4310	131	13	citrulline	citrulline	NOUN
easat-4310	131	14	dynamics	dynamic	NOUN
easat-4310	131	15	in	in	ADP
easat-4310	131	16	high	high	ADJ
easat-4310	131	17	-	-	PUNCT
easat-4310	131	18	risk	risk	NOUN
easat-4310	131	19	patients	patient	NOUN
easat-4310	131	20	.	.	PUNCT
easat-4310	132	1	malnutrition	malnutrition	NOUN
easat-4310	132	2	,	,	PUNCT
easat-4310	132	3	which	which	PRON
easat-4310	132	4	remains	remain	VERB
easat-4310	132	5	a	a	DET
easat-4310	132	6	significant	significant	ADJ
easat-4310	132	7	public	public	ADJ
easat-4310	132	8	health	health	NOUN
easat-4310	132	9	issue	issue	NOUN
easat-4310	132	10	in	in	ADP
easat-4310	132	11	indonesia	indonesia	PROPN
easat-4310	132	12	,	,	PUNCT
easat-4310	132	13	can	can	AUX
easat-4310	132	14	impair	impair	VERB
easat-4310	132	15	intestinal	intestinal	ADJ
easat-4310	132	16	function	function	NOUN
easat-4310	132	17	and	and	CCONJ
easat-4310	132	18	regenerative	regenerative	ADJ
easat-4310	132	19	capacity	capacity	NOUN
easat-4310	132	20	.	.	PUNCT
easat-4310	133	1	undernourished	undernourished	ADJ
easat-4310	133	2	patients	patient	NOUN
easat-4310	133	3	may	may	AUX
easat-4310	133	4	exhibit	exhibit	VERB
easat-4310	133	5	reduced	reduce	VERB
easat-4310	133	6	baseline	baseline	ADJ
easat-4310	133	7	citrulline	citrulline	NOUN
easat-4310	133	8	levels	level	NOUN
easat-4310	133	9	due	due	ADJ
easat-4310	133	10	to	to	ADP
easat-4310	133	11	compromised	compromise	VERB
easat-4310	133	12	enterocyte	enterocyte	PROPN
easat-4310	133	13	mass	mass	PROPN
easat-4310	133	14	,	,	PUNCT
easat-4310	133	15	potentially	potentially	ADV
easat-4310	133	16	amplifying	amplify	VERB
easat-4310	133	17	the	the	DET
easat-4310	133	18	impact	impact	NOUN
easat-4310	133	19	of	of	ADP
easat-4310	133	20	chemotherapy	chemotherapy	NOUN
easat-4310	133	21	-	-	PUNCT
easat-4310	133	22	induced	induce	VERB
easat-4310	133	23	injury	injury	NOUN
easat-4310	133	24	[	[	X
easat-4310	133	25	23	23	NUM
easat-4310	133	26	]	]	PUNCT
easat-4310	133	27	.	.	PUNCT
easat-4310	134	1	conversely	conversely	ADV
easat-4310	134	2	,	,	PUNCT
easat-4310	134	3	overnutrition	overnutrition	NOUN
easat-4310	134	4	,	,	PUNCT
easat-4310	134	5	characterized	characterize	VERB
easat-4310	134	6	by	by	ADP
easat-4310	134	7	excess	excess	ADJ
easat-4310	134	8	adiposity	adiposity	NOUN
easat-4310	134	9	,	,	PUNCT
easat-4310	134	10	may	may	AUX
easat-4310	134	11	be	be	AUX
easat-4310	134	12	associated	associate	VERB
easat-4310	134	13	with	with	ADP
easat-4310	134	14	chronic	chronic	ADJ
easat-4310	134	15	low	low	ADJ
easat-4310	134	16	-	-	PUNCT
easat-4310	134	17	grade	grade	NOUN
easat-4310	134	18	inflammation	inflammation	NOUN
easat-4310	134	19	,	,	PUNCT
easat-4310	134	20	further	far	ADV
easat-4310	134	21	complicating	complicate	VERB
easat-4310	134	22	citrulline	citrulline	ADJ
easat-4310	134	23	interpretation	interpretation	NOUN
easat-4310	134	24	[	[	X
easat-4310	134	25	24	24	NUM
easat-4310	134	26	]	]	PUNCT
easat-4310	134	27	.	.	PUNCT
easat-4310	135	1	the	the	DET
easat-4310	135	2	dual	dual	ADJ
easat-4310	135	3	burden	burden	NOUN
easat-4310	135	4	of	of	ADP
easat-4310	135	5	malnutrition	malnutrition	NOUN
easat-4310	135	6	in	in	ADP
easat-4310	135	7	indonesia	indonesia	PROPN
easat-4310	135	8	necessitates	necessitate	VERB
easat-4310	135	9	a	a	DET
easat-4310	135	10	nuanced	nuanced	ADJ
easat-4310	135	11	understanding	understanding	NOUN
easat-4310	135	12	of	of	ADP
easat-4310	135	13	how	how	SCONJ
easat-4310	135	14	nutritional	nutritional	ADJ
easat-4310	135	15	status	status	NOUN
easat-4310	135	16	interacts	interact	VERB
easat-4310	135	17	with	with	ADP
easat-4310	135	18	citrulline	citrulline	NOUN
easat-4310	135	19	dynamics	dynamic	NOUN
easat-4310	135	20	in	in	ADP
easat-4310	135	21	this	this	DET
easat-4310	135	22	population	population	NOUN
easat-4310	136	1	[	[	X
easat-4310	136	2	10	10	NUM
easat-4310	136	3	]	]	PUNCT
easat-4310	136	4	.	.	PUNCT
easat-4310	137	1	it	it	PRON
easat-4310	137	2	is	be	AUX
easat-4310	137	3	also	also	ADV
easat-4310	137	4	worth	worth	ADJ
easat-4310	137	5	considering	consider	VERB
easat-4310	137	6	the	the	DET
easat-4310	137	7	potential	potential	ADJ
easat-4310	137	8	impact	impact	NOUN
easat-4310	137	9	of	of	ADP
easat-4310	137	10	chemotherapy	chemotherapy	NOUN
easat-4310	137	11	regimen	regimen	NOUN
easat-4310	137	12	differences	difference	NOUN
easat-4310	137	13	on	on	ADP
easat-4310	137	14	citrulline	citrulline	NOUN
easat-4310	137	15	dynamics	dynamic	NOUN
easat-4310	137	16	.	.	PUNCT
easat-4310	138	1	variations	variation	NOUN
easat-4310	138	2	in	in	ADP
easat-4310	138	3	methotrexate	methotrexate	NOUN
easat-4310	138	4	dosing	dose	VERB
easat-4310	138	5	protocols	protocol	NOUN
easat-4310	138	6	,	,	PUNCT
easat-4310	138	7	supportive	supportive	ADJ
easat-4310	138	8	care	care	NOUN
easat-4310	138	9	measures	measure	NOUN
easat-4310	138	10	,	,	PUNCT
easat-4310	138	11	and	and	CCONJ
easat-4310	138	12	adjunctive	adjunctive	ADJ
easat-4310	138	13	therapies	therapy	NOUN
easat-4310	138	14	could	could	AUX
easat-4310	138	15	influence	influence	VERB
easat-4310	138	16	the	the	DET
easat-4310	138	17	extent	extent	NOUN
easat-4310	138	18	of	of	ADP
easat-4310	138	19	mucosal	mucosal	NOUN
easat-4310	138	20	injury	injury	NOUN
easat-4310	138	21	and	and	CCONJ
easat-4310	138	22	subsequent	subsequent	ADJ
easat-4310	138	23	citrulline	citrulline	NOUN
easat-4310	138	24	responses	response	NOUN
easat-4310	138	25	.	.	PUNCT
easat-4310	139	1	for	for	ADP
easat-4310	139	2	instance	instance	NOUN
easat-4310	139	3	,	,	PUNCT
easat-4310	139	4	differences	difference	NOUN
easat-4310	139	5	in	in	ADP
easat-4310	139	6	the	the	DET
easat-4310	139	7	use	use	NOUN
easat-4310	139	8	of	of	ADP
easat-4310	139	9	leucovorin	leucovorin	NOUN
easat-4310	139	10	rescue	rescue	NOUN
easat-4310	139	11	or	or	CCONJ
easat-4310	139	12	anti	anti	ADJ
easat-4310	139	13	-	-	ADJ
easat-4310	139	14	inflammatory	inflammatory	ADJ
easat-4310	139	15	agents	agent	NOUN
easat-4310	139	16	may	may	AUX
easat-4310	139	17	alter	alter	VERB
easat-4310	139	18	the	the	DET
easat-4310	139	19	trajectory	trajectory	NOUN
easat-4310	139	20	of	of	ADP
easat-4310	139	21	mucosal	mucosal	NOUN
easat-4310	139	22	recovery	recovery	NOUN
easat-4310	139	23	,	,	PUNCT
easat-4310	139	24	contributing	contribute	VERB
easat-4310	139	25	to	to	ADP
easat-4310	139	26	the	the	DET
easat-4310	139	27	heterogeneity	heterogeneity	NOUN
easat-4310	139	28	observed	observe	VERB
easat-4310	139	29	in	in	ADP
easat-4310	139	30	high	high	ADJ
easat-4310	139	31	-	-	PUNCT
easat-4310	139	32	risk	risk	NOUN
easat-4310	139	33	patients	patient	NOUN
easat-4310	139	34	[	[	X
easat-4310	139	35	25	25	NUM
easat-4310	139	36	]	]	PUNCT
easat-4310	139	37	.	.	PUNCT
easat-4310	140	1	understanding	understand	VERB
easat-4310	140	2	these	these	DET
easat-4310	140	3	regimen	regimen	NOUN
easat-4310	140	4	-	-	PUNCT
easat-4310	140	5	specific	specific	ADJ
easat-4310	140	6	effects	effect	NOUN
easat-4310	140	7	is	be	AUX
easat-4310	140	8	critical	critical	ADJ
easat-4310	140	9	for	for	ADP
easat-4310	140	10	standardizing	standardize	VERB
easat-4310	140	11	citrulline	citrulline	NOUN
easat-4310	140	12	-	-	PUNCT
easat-4310	140	13	based	base	VERB
easat-4310	140	14	monitoring	monitoring	NOUN
easat-4310	140	15	protocols	protocol	NOUN
easat-4310	140	16	and	and	CCONJ
easat-4310	140	17	ensuring	ensure	VERB
easat-4310	140	18	their	their	PRON
easat-4310	140	19	validity	validity	NOUN
easat-4310	140	20	across	across	ADP
easat-4310	140	21	diverse	diverse	ADJ
easat-4310	140	22	clinical	clinical	ADJ
easat-4310	140	23	settings	setting	NOUN
easat-4310	140	24	.	.	PUNCT
easat-4310	141	1	lastly	lastly	ADV
easat-4310	141	2	,	,	PUNCT
easat-4310	141	3	socioeconomic	socioeconomic	ADJ
easat-4310	141	4	and	and	CCONJ
easat-4310	141	5	environmental	environmental	ADJ
easat-4310	141	6	factors	factor	NOUN
easat-4310	141	7	in	in	ADP
easat-4310	141	8	indonesia	indonesia	PROPN
easat-4310	141	9	,	,	PUNCT
easat-4310	141	10	including	include	VERB
easat-4310	141	11	disparities	disparity	NOUN
easat-4310	141	12	in	in	ADP
easat-4310	141	13	healthcare	healthcare	NOUN
easat-4310	141	14	access	access	NOUN
easat-4310	141	15	,	,	PUNCT
easat-4310	141	16	delayed	delay	VERB
easat-4310	141	17	diagnosis	diagnosis	NOUN
easat-4310	141	18	,	,	PUNCT
easat-4310	141	19	and	and	CCONJ
easat-4310	141	20	inconsistent	inconsistent	ADJ
easat-4310	141	21	supportive	supportive	ADJ
easat-4310	141	22	care	care	NOUN
easat-4310	141	23	,	,	PUNCT
easat-4310	141	24	exacerbate	exacerbate	VERB
easat-4310	141	25	disease	disease	NOUN
easat-4310	141	26	severity	severity	NOUN
easat-4310	141	27	and	and	CCONJ
easat-4310	141	28	complicate	complicate	VERB
easat-4310	141	29	treatment	treatment	NOUN
easat-4310	141	30	outcomes	outcome	NOUN
easat-4310	141	31	.	.	PUNCT
easat-4310	142	1	these	these	DET
easat-4310	142	2	challenges	challenge	NOUN
easat-4310	142	3	may	may	AUX
easat-4310	142	4	amplify	amplify	VERB
easat-4310	142	5	the	the	DET
easat-4310	142	6	biological	biological	ADJ
easat-4310	142	7	variability	variability	NOUN
easat-4310	142	8	in	in	ADP
easat-4310	142	9	citrulline	citrulline	NOUN
easat-4310	142	10	responses	response	NOUN
easat-4310	142	11	,	,	PUNCT
easat-4310	142	12	underscoring	underscore	VERB
easat-4310	142	13	the	the	DET
easat-4310	142	14	need	need	NOUN
easat-4310	142	15	to	to	PART
easat-4310	142	16	tailor	tailor	VERB
easat-4310	142	17	biomarker	biomarker	NOUN
easat-4310	142	18	strategies	strategy	NOUN
easat-4310	142	19	to	to	ADP
easat-4310	142	20	the	the	DET
easat-4310	142	21	local	local	ADJ
easat-4310	142	22	context	context	NOUN
easat-4310	142	23	[	[	X
easat-4310	142	24	26	26	NUM
easat-4310	142	25	]	]	PUNCT
easat-4310	142	26	.	.	PUNCT
easat-4310	143	1	the	the	DET
easat-4310	143	2	relationship	relationship	NOUN
easat-4310	143	3	between	between	ADP
easat-4310	143	4	mucositis	mucositis	NOUN
easat-4310	143	5	severity	severity	NOUN
easat-4310	143	6	and	and	CCONJ
easat-4310	143	7	citrulline	citrulline	NOUN
easat-4310	143	8	dynamics	dynamic	NOUN
easat-4310	143	9	underscores	underscore	VERB
easat-4310	143	10	the	the	DET
easat-4310	143	11	complexity	complexity	NOUN
easat-4310	143	12	of	of	ADP
easat-4310	143	13	using	use	VERB
easat-4310	143	14	this	this	DET
easat-4310	143	15	biomarker	biomarker	NOUN
easat-4310	143	16	to	to	PART
easat-4310	143	17	monitor	monitor	VERB
easat-4310	143	18	gastrointestinal	gastrointestinal	ADJ
easat-4310	143	19	health	health	NOUN
easat-4310	143	20	.	.	PUNCT
easat-4310	144	1	in	in	ADP
easat-4310	144	2	this	this	DET
easat-4310	144	3	study	study	NOUN
easat-4310	144	4	,	,	PUNCT
easat-4310	144	5	patients	patient	NOUN
easat-4310	144	6	with	with	ADP
easat-4310	144	7	grade	grade	NOUN
easat-4310	144	8	1	1	NUM
easat-4310	144	9	mucositis	mucositis	NOUN
easat-4310	144	10	exhibited	exhibit	VERB
easat-4310	144	11	a	a	DET
easat-4310	144	12	significant	significant	ADJ
easat-4310	144	13	increase	increase	NOUN
easat-4310	144	14	in	in	ADP
easat-4310	144	15	citrulline	citrulline	NOUN
easat-4310	144	16	levels	level	NOUN
easat-4310	144	17	post	post	ADJ
easat-4310	144	18	-	-	NOUN
easat-4310	144	19	chemotherapy	chemotherapy	ADJ
easat-4310	144	20	,	,	PUNCT
easat-4310	144	21	likely	likely	ADV
easat-4310	144	22	reflecting	reflect	VERB
easat-4310	144	23	early	early	ADJ
easat-4310	144	24	enterocyte	enterocyte	NOUN
easat-4310	144	25	recovery	recovery	NOUN
easat-4310	144	26	and	and	CCONJ
easat-4310	144	27	regeneration	regeneration	NOUN
easat-4310	144	28	.	.	PUNCT
easat-4310	145	1	this	this	DET
easat-4310	145	2	finding	find	VERB
easat-4310	145	3	highlights	highlight	VERB
easat-4310	145	4	citrulline	citrulline	NOUN
easat-4310	145	5	's	's	PART
easat-4310	145	6	dual	dual	ADJ
easat-4310	145	7	role	role	NOUN
easat-4310	145	8	—	—	PUNCT
easat-4310	145	9	not	not	PART
easat-4310	145	10	only	only	ADV
easat-4310	145	11	as	as	ADP
easat-4310	145	12	an	an	DET
easat-4310	145	13	indicator	indicator	NOUN
easat-4310	145	14	of	of	ADP
easat-4310	145	15	mucosal	mucosal	NOUN
easat-4310	145	16	injury	injury	NOUN
easat-4310	145	17	but	but	CCONJ
easat-4310	145	18	also	also	ADV
easat-4310	145	19	as	as	ADP
easat-4310	145	20	a	a	DET
easat-4310	145	21	marker	marker	NOUN
easat-4310	145	22	of	of	ADP
easat-4310	145	23	repair	repair	NOUN
easat-4310	145	24	processes	process	NOUN
easat-4310	145	25	[	[	X
easat-4310	145	26	12	12	NUM
easat-4310	145	27	]	]	PUNCT
easat-4310	145	28	.	.	PUNCT
easat-4310	146	1	early	early	ADJ
easat-4310	146	2	regenerative	regenerative	ADJ
easat-4310	146	3	responses	response	NOUN
easat-4310	146	4	in	in	ADP
easat-4310	146	5	grade	grade	NOUN
easat-4310	146	6	1	1	NUM
easat-4310	146	7	mucositis	mucositis	NOUN
easat-4310	146	8	may	may	AUX
easat-4310	146	9	involve	involve	VERB
easat-4310	146	10	proliferation	proliferation	NOUN
easat-4310	146	11	of	of	ADP
easat-4310	146	12	intestinal	intestinal	ADJ
easat-4310	146	13	epithelial	epithelial	ADJ
easat-4310	146	14	stem	stem	NOUN
easat-4310	146	15	cells	cell	NOUN
easat-4310	146	16	and	and	CCONJ
easat-4310	146	17	restoration	restoration	NOUN
easat-4310	146	18	of	of	ADP
easat-4310	146	19	the	the	DET
easat-4310	146	20	mucosal	mucosal	NOUN
easat-4310	146	21	barrier	barrier	NOUN
easat-4310	146	22	,	,	PUNCT
easat-4310	146	23	which	which	PRON
easat-4310	146	24	collectively	collectively	ADV
easat-4310	146	25	boost	boost	VERB
easat-4310	146	26	citrulline	citrulline	NOUN
easat-4310	146	27	synthesis	synthesis	NOUN
easat-4310	146	28	and	and	CCONJ
easat-4310	146	29	contribute	contribute	VERB
easat-4310	146	30	to	to	ADP
easat-4310	146	31	elevated	elevated	ADJ
easat-4310	146	32	serum	serum	NOUN
easat-4310	146	33	levels	level	NOUN
easat-4310	146	34	[	[	X
easat-4310	146	35	16	16	NUM
easat-4310	146	36	]	]	PUNCT
easat-4310	146	37	.	.	PUNCT
easat-4310	147	1	in	in	ADP
easat-4310	147	2	contrast	contrast	NOUN
easat-4310	147	3	,	,	PUNCT
easat-4310	147	4	patients	patient	NOUN
easat-4310	147	5	1083	1083	NUM
easat-4310	147	6	edelweiss	edelweiss	PROPN
easat-4310	147	7	applied	apply	VERB
easat-4310	147	8	science	science	NOUN
easat-4310	147	9	and	and	CCONJ
easat-4310	147	10	technology	technology	NOUN
easat-4310	147	11	issn	issn	PROPN
easat-4310	147	12	:	:	PUNCT
easat-4310	147	13	2576	2576	NUM
easat-4310	147	14	-	-	SYM
easat-4310	147	15	8484	8484	NUM
easat-4310	147	16	vol	vol	NOUN
easat-4310	147	17	.	.	PROPN
easat-4310	148	1	9	9	NUM
easat-4310	148	2	,	,	PUNCT
easat-4310	148	3	no	no	INTJ
easat-4310	148	4	.	.	NOUN
easat-4310	148	5	1	1	NUM
easat-4310	148	6	:	:	SYM
easat-4310	148	7	1078	1078	NUM
easat-4310	148	8	-	-	SYM
easat-4310	148	9	1085	1085	NUM
easat-4310	148	10	,	,	PUNCT
easat-4310	148	11	2025	2025	NUM
easat-4310	148	12	doi	doi	NOUN
easat-4310	148	13	:	:	PUNCT
easat-4310	148	14	10.55214/25768484.v9i1.4310	10.55214/25768484.v9i1.4310	NUM
easat-4310	148	15	©	©	PROPN
easat-4310	148	16	2025	2025	NUM
easat-4310	148	17	by	by	ADP
easat-4310	148	18	the	the	DET
easat-4310	148	19	authors	author	NOUN
easat-4310	148	20	;	;	PUNCT
easat-4310	148	21	licensee	licensee	PROPN
easat-4310	148	22	learning	learning	NOUN
easat-4310	148	23	gate	gate	NOUN
easat-4310	148	24	with	with	ADP
easat-4310	148	25	grade	grade	NOUN
easat-4310	148	26	2	2	NUM
easat-4310	148	27	mucositis	mucositis	NOUN
easat-4310	148	28	showed	show	VERB
easat-4310	148	29	no	no	DET
easat-4310	148	30	significant	significant	ADJ
easat-4310	148	31	change	change	NOUN
easat-4310	148	32	in	in	ADP
easat-4310	148	33	citrulline	citrulline	NOUN
easat-4310	148	34	levels	level	NOUN
easat-4310	148	35	.	.	PUNCT
easat-4310	149	1	this	this	DET
easat-4310	149	2	lack	lack	NOUN
easat-4310	149	3	of	of	ADP
easat-4310	149	4	variation	variation	NOUN
easat-4310	149	5	likely	likely	ADV
easat-4310	149	6	reflects	reflect	VERB
easat-4310	149	7	severe	severe	ADJ
easat-4310	149	8	and	and	CCONJ
easat-4310	149	9	sustained	sustained	ADJ
easat-4310	149	10	mucosal	mucosal	NOUN
easat-4310	149	11	damage	damage	NOUN
easat-4310	149	12	that	that	PRON
easat-4310	149	13	overwhelms	overwhelm	VERB
easat-4310	149	14	the	the	DET
easat-4310	149	15	intestine	intestine	NOUN
easat-4310	149	16	’s	’s	PART
easat-4310	149	17	capacity	capacity	NOUN
easat-4310	149	18	for	for	ADP
easat-4310	149	19	repair	repair	NOUN
easat-4310	149	20	.	.	PUNCT
easat-4310	150	1	in	in	ADP
easat-4310	150	2	grade	grade	NOUN
easat-4310	150	3	2	2	NUM
easat-4310	150	4	mucositis	mucositis	NOUN
easat-4310	150	5	,	,	PUNCT
easat-4310	150	6	the	the	DET
easat-4310	150	7	extent	extent	NOUN
easat-4310	150	8	of	of	ADP
easat-4310	150	9	epithelial	epithelial	ADJ
easat-4310	150	10	injury	injury	NOUN
easat-4310	150	11	may	may	AUX
easat-4310	150	12	be	be	AUX
easat-4310	150	13	so	so	ADV
easat-4310	150	14	profound	profound	ADJ
easat-4310	150	15	that	that	SCONJ
easat-4310	150	16	compensatory	compensatory	ADJ
easat-4310	150	17	mechanisms	mechanism	NOUN
easat-4310	150	18	,	,	PUNCT
easat-4310	150	19	such	such	ADJ
easat-4310	150	20	as	as	ADP
easat-4310	150	21	enterocyte	enterocyte	NOUN
easat-4310	150	22	proliferation	proliferation	NOUN
easat-4310	150	23	,	,	PUNCT
easat-4310	150	24	are	be	AUX
easat-4310	150	25	either	either	CCONJ
easat-4310	150	26	insufficient	insufficient	ADJ
easat-4310	150	27	or	or	CCONJ
easat-4310	150	28	delayed	delay	VERB
easat-4310	150	29	[	[	X
easat-4310	150	30	11	11	NUM
easat-4310	150	31	]	]	PUNCT
easat-4310	150	32	.	.	PUNCT
easat-4310	151	1	this	this	PRON
easat-4310	151	2	supports	support	VERB
easat-4310	151	3	the	the	DET
easat-4310	151	4	idea	idea	NOUN
easat-4310	151	5	that	that	SCONJ
easat-4310	151	6	citrulline	citrulline	NOUN
easat-4310	151	7	levels	level	NOUN
easat-4310	151	8	reflect	reflect	VERB
easat-4310	151	9	a	a	DET
easat-4310	151	10	dynamic	dynamic	ADJ
easat-4310	151	11	balance	balance	NOUN
easat-4310	151	12	between	between	ADP
easat-4310	151	13	injury	injury	NOUN
easat-4310	151	14	and	and	CCONJ
easat-4310	151	15	regeneration	regeneration	NOUN
easat-4310	151	16	,	,	PUNCT
easat-4310	151	17	with	with	ADP
easat-4310	151	18	severe	severe	ADJ
easat-4310	151	19	mucositis	mucositis	NOUN
easat-4310	151	20	tipping	tip	VERB
easat-4310	151	21	this	this	DET
easat-4310	151	22	balance	balance	NOUN
easat-4310	151	23	toward	toward	ADP
easat-4310	151	24	persistent	persistent	ADJ
easat-4310	151	25	damage	damage	NOUN
easat-4310	151	26	and	and	CCONJ
easat-4310	151	27	impaired	impaired	ADJ
easat-4310	151	28	function	function	NOUN
easat-4310	151	29	.	.	PUNCT
easat-4310	152	1	the	the	DET
easat-4310	152	2	disparity	disparity	NOUN
easat-4310	152	3	between	between	ADP
easat-4310	152	4	grade	grade	NOUN
easat-4310	152	5	1	1	NUM
easat-4310	152	6	and	and	CCONJ
easat-4310	152	7	grade	grade	NOUN
easat-4310	152	8	2	2	NUM
easat-4310	152	9	mucositis	mucositis	NOUN
easat-4310	152	10	patients	patient	NOUN
easat-4310	152	11	also	also	ADV
easat-4310	152	12	raises	raise	VERB
easat-4310	152	13	questions	question	NOUN
easat-4310	152	14	about	about	ADP
easat-4310	152	15	the	the	DET
easat-4310	152	16	temporal	temporal	ADJ
easat-4310	152	17	aspects	aspect	NOUN
easat-4310	152	18	of	of	ADP
easat-4310	152	19	mucosal	mucosal	ADJ
easat-4310	152	20	healing	healing	NOUN
easat-4310	152	21	.	.	PUNCT
easat-4310	153	1	it	it	PRON
easat-4310	153	2	is	be	AUX
easat-4310	153	3	possible	possible	ADJ
easat-4310	153	4	that	that	SCONJ
easat-4310	153	5	recovery	recovery	NOUN
easat-4310	153	6	in	in	ADP
easat-4310	153	7	grade	grade	NOUN
easat-4310	153	8	2	2	NUM
easat-4310	153	9	mucositis	mucositis	NOUN
easat-4310	153	10	requires	require	VERB
easat-4310	153	11	a	a	DET
easat-4310	153	12	longer	long	ADJ
easat-4310	153	13	timeframe	timeframe	NOUN
easat-4310	153	14	,	,	PUNCT
easat-4310	153	15	during	during	ADP
easat-4310	153	16	which	which	PRON
easat-4310	153	17	citrulline	citrulline	NOUN
easat-4310	153	18	levels	level	NOUN
easat-4310	153	19	may	may	AUX
easat-4310	153	20	eventually	eventually	ADV
easat-4310	153	21	normalize	normalize	VERB
easat-4310	153	22	or	or	CCONJ
easat-4310	153	23	increase	increase	VERB
easat-4310	153	24	.	.	PUNCT
easat-4310	154	1	this	this	PRON
easat-4310	154	2	suggests	suggest	VERB
easat-4310	154	3	that	that	SCONJ
easat-4310	154	4	single	single	ADJ
easat-4310	154	5	time	time	NOUN
easat-4310	154	6	-	-	PUNCT
easat-4310	154	7	point	point	NOUN
easat-4310	154	8	measurements	measurement	NOUN
easat-4310	154	9	may	may	AUX
easat-4310	154	10	not	not	PART
easat-4310	154	11	fully	fully	ADV
easat-4310	154	12	capture	capture	VERB
easat-4310	154	13	the	the	DET
easat-4310	154	14	progression	progression	NOUN
easat-4310	154	15	of	of	ADP
easat-4310	154	16	mucosal	mucosal	NOUN
easat-4310	154	17	injury	injury	NOUN
easat-4310	154	18	and	and	CCONJ
easat-4310	154	19	repair	repair	NOUN
easat-4310	154	20	,	,	PUNCT
easat-4310	154	21	emphasizing	emphasize	VERB
easat-4310	154	22	the	the	DET
easat-4310	154	23	need	need	NOUN
easat-4310	154	24	for	for	ADP
easat-4310	154	25	longitudinal	longitudinal	ADJ
easat-4310	154	26	monitoring	monitoring	NOUN
easat-4310	154	27	to	to	PART
easat-4310	154	28	provide	provide	VERB
easat-4310	154	29	a	a	DET
easat-4310	154	30	more	more	ADV
easat-4310	154	31	comprehensive	comprehensive	ADJ
easat-4310	154	32	understanding	understanding	NOUN
easat-4310	154	33	of	of	ADP
easat-4310	154	34	citrulline	citrulline	NOUN
easat-4310	154	35	's	's	PART
easat-4310	154	36	behavior	behavior	NOUN
easat-4310	154	37	over	over	ADP
easat-4310	154	38	time	time	NOUN
easat-4310	154	39	[	[	X
easat-4310	154	40	17	17	NUM
easat-4310	154	41	]	]	PUNCT
easat-4310	154	42	.	.	PUNCT
easat-4310	155	1	these	these	DET
easat-4310	155	2	findings	finding	NOUN
easat-4310	155	3	emphasize	emphasize	VERB
easat-4310	155	4	the	the	DET
easat-4310	155	5	need	need	NOUN
easat-4310	155	6	for	for	ADP
easat-4310	155	7	a	a	DET
easat-4310	155	8	nuanced	nuanced	ADJ
easat-4310	155	9	approach	approach	NOUN
easat-4310	155	10	to	to	ADP
easat-4310	155	11	interpreting	interpret	VERB
easat-4310	155	12	citrulline	citrulline	NOUN
easat-4310	155	13	levels	level	NOUN
easat-4310	155	14	in	in	ADP
easat-4310	155	15	the	the	DET
easat-4310	155	16	context	context	NOUN
easat-4310	155	17	of	of	ADP
easat-4310	155	18	mucositis	mucositis	PROPN
easat-4310	155	19	severity	severity	NOUN
easat-4310	155	20	.	.	PUNCT
easat-4310	156	1	understanding	understand	VERB
easat-4310	156	2	the	the	DET
easat-4310	156	3	interplay	interplay	NOUN
easat-4310	156	4	between	between	ADP
easat-4310	156	5	injury	injury	NOUN
easat-4310	156	6	and	and	CCONJ
easat-4310	156	7	regeneration	regeneration	NOUN
easat-4310	156	8	is	be	AUX
easat-4310	156	9	crucial	crucial	ADJ
easat-4310	156	10	for	for	ADP
easat-4310	156	11	optimizing	optimize	VERB
easat-4310	156	12	the	the	DET
easat-4310	156	13	use	use	NOUN
easat-4310	156	14	of	of	ADP
easat-4310	156	15	citrulline	citrulline	NOUN
easat-4310	156	16	as	as	ADP
easat-4310	156	17	a	a	DET
easat-4310	156	18	biomarker	biomarker	NOUN
easat-4310	156	19	in	in	ADP
easat-4310	156	20	pediatric	pediatric	ADJ
easat-4310	156	21	oncology	oncology	NOUN
easat-4310	156	22	,	,	PUNCT
easat-4310	156	23	particularly	particularly	ADV
easat-4310	156	24	in	in	ADP
easat-4310	156	25	tailoring	tailor	VERB
easat-4310	156	26	interventions	intervention	NOUN
easat-4310	156	27	to	to	PART
easat-4310	156	28	support	support	VERB
easat-4310	156	29	mucosal	mucosal	NOUN
easat-4310	156	30	recovery	recovery	NOUN
easat-4310	156	31	in	in	ADP
easat-4310	156	32	patients	patient	NOUN
easat-4310	156	33	with	with	ADP
easat-4310	156	34	severe	severe	ADJ
easat-4310	156	35	mucositis	mucositis	NOUN
easat-4310	157	1	[	[	X
easat-4310	157	2	19	19	NUM
easat-4310	157	3	]	]	PUNCT
easat-4310	157	4	.	.	PUNCT
easat-4310	158	1	while	while	SCONJ
easat-4310	158	2	citrulline	citrulline	NOUN
easat-4310	158	3	shows	show	VERB
easat-4310	158	4	promise	promise	NOUN
easat-4310	158	5	as	as	ADP
easat-4310	158	6	a	a	DET
easat-4310	158	7	noninvasive	noninvasive	ADJ
easat-4310	158	8	biomarker	biomarker	NOUN
easat-4310	158	9	for	for	ADP
easat-4310	158	10	gastrointestinal	gastrointestinal	ADJ
easat-4310	158	11	mucositis	mucositis	NOUN
easat-4310	158	12	,	,	PUNCT
easat-4310	158	13	this	this	DET
easat-4310	158	14	study	study	NOUN
easat-4310	158	15	highlights	highlight	VERB
easat-4310	158	16	several	several	ADJ
easat-4310	158	17	limitations	limitation	NOUN
easat-4310	158	18	that	that	PRON
easat-4310	158	19	must	must	AUX
easat-4310	158	20	be	be	AUX
easat-4310	158	21	addressed	address	VERB
easat-4310	158	22	to	to	PART
easat-4310	158	23	optimize	optimize	VERB
easat-4310	158	24	its	its	PRON
easat-4310	158	25	clinical	clinical	ADJ
easat-4310	158	26	utility	utility	NOUN
easat-4310	158	27	.	.	PUNCT
easat-4310	159	1	the	the	DET
easat-4310	159	2	observed	observe	VERB
easat-4310	159	3	variability	variability	NOUN
easat-4310	159	4	across	across	ADP
easat-4310	159	5	risk	risk	NOUN
easat-4310	159	6	groups	group	NOUN
easat-4310	159	7	and	and	CCONJ
easat-4310	159	8	mucositis	mucositis	NOUN
easat-4310	159	9	grades	grade	NOUN
easat-4310	159	10	suggests	suggest	VERB
easat-4310	159	11	that	that	SCONJ
easat-4310	159	12	citrulline	citrulline	NOUN
easat-4310	159	13	levels	level	NOUN
easat-4310	159	14	are	be	AUX
easat-4310	159	15	influenced	influence	VERB
easat-4310	159	16	by	by	ADP
easat-4310	159	17	a	a	DET
easat-4310	159	18	complex	complex	ADJ
easat-4310	159	19	interplay	interplay	NOUN
easat-4310	159	20	of	of	ADP
easat-4310	159	21	factors	factor	NOUN
easat-4310	159	22	beyond	beyond	ADP
easat-4310	159	23	enterocyte	enterocyte	NOUN
easat-4310	159	24	mass	mass	PROPN
easat-4310	160	1	[	[	X
easat-4310	160	2	12	12	NUM
easat-4310	160	3	]	]	PUNCT
easat-4310	160	4	.	.	PUNCT
easat-4310	161	1	nutritional	nutritional	ADJ
easat-4310	161	2	status	status	NOUN
easat-4310	161	3	is	be	AUX
easat-4310	161	4	one	one	NUM
easat-4310	161	5	significant	significant	ADJ
easat-4310	161	6	factor	factor	NOUN
easat-4310	161	7	affecting	affect	VERB
easat-4310	161	8	citrulline	citrulline	NOUN
easat-4310	161	9	levels	level	NOUN
easat-4310	161	10	.	.	PUNCT
easat-4310	162	1	malnutrition	malnutrition	NOUN
easat-4310	162	2	,	,	PUNCT
easat-4310	162	3	prevalent	prevalent	NOUN
easat-4310	162	4	in	in	ADP
easat-4310	162	5	pediatric	pediatric	ADJ
easat-4310	162	6	oncology	oncology	NOUN
easat-4310	162	7	populations	population	NOUN
easat-4310	162	8	,	,	PUNCT
easat-4310	162	9	can	can	AUX
easat-4310	162	10	compromise	compromise	VERB
easat-4310	162	11	baseline	baseline	PROPN
easat-4310	162	12	enterocyte	enterocyte	PROPN
easat-4310	162	13	mass	mass	PROPN
easat-4310	162	14	,	,	PUNCT
easat-4310	162	15	thereby	thereby	ADV
easat-4310	162	16	reducing	reduce	VERB
easat-4310	162	17	citrulline	citrulline	NOUN
easat-4310	162	18	levels	level	NOUN
easat-4310	162	19	.	.	PUNCT
easat-4310	163	1	conversely	conversely	ADV
easat-4310	163	2	,	,	PUNCT
easat-4310	163	3	chronic	chronic	ADJ
easat-4310	163	4	low	low	ADJ
easat-4310	163	5	-	-	PUNCT
easat-4310	163	6	grade	grade	NOUN
easat-4310	163	7	inflammation	inflammation	NOUN
easat-4310	163	8	in	in	ADP
easat-4310	163	9	overnourished	overnourished	ADJ
easat-4310	163	10	patients	patient	NOUN
easat-4310	163	11	can	can	AUX
easat-4310	163	12	exacerbate	exacerbate	VERB
easat-4310	163	13	intestinal	intestinal	ADJ
easat-4310	163	14	permeability	permeability	NOUN
easat-4310	163	15	and	and	CCONJ
easat-4310	163	16	alter	alter	VERB
easat-4310	163	17	citrulline	citrulline	NOUN
easat-4310	163	18	synthesis	synthesis	NOUN
easat-4310	164	1	[	[	X
easat-4310	164	2	27	27	NUM
easat-4310	164	3	]	]	PUNCT
easat-4310	164	4	.	.	PUNCT
easat-4310	165	1	renal	renal	ADJ
easat-4310	165	2	function	function	NOUN
easat-4310	165	3	is	be	AUX
easat-4310	165	4	another	another	DET
easat-4310	165	5	critical	critical	ADJ
easat-4310	165	6	determinant	determinant	ADJ
easat-4310	165	7	,	,	PUNCT
easat-4310	165	8	as	as	SCONJ
easat-4310	165	9	citrulline	citrulline	NOUN
easat-4310	165	10	clearance	clearance	NOUN
easat-4310	165	11	occurs	occur	VERB
easat-4310	165	12	primarily	primarily	ADV
easat-4310	165	13	in	in	ADP
easat-4310	165	14	the	the	DET
easat-4310	165	15	kidneys	kidney	NOUN
easat-4310	165	16	.	.	PUNCT
easat-4310	166	1	variations	variation	NOUN
easat-4310	166	2	in	in	ADP
easat-4310	166	3	renal	renal	ADJ
easat-4310	166	4	efficiency	efficiency	NOUN
easat-4310	166	5	,	,	PUNCT
easat-4310	166	6	particularly	particularly	ADV
easat-4310	166	7	in	in	ADP
easat-4310	166	8	patients	patient	NOUN
easat-4310	166	9	receiving	receive	VERB
easat-4310	166	10	nephrotoxic	nephrotoxic	ADJ
easat-4310	166	11	chemotherapy	chemotherapy	NOUN
easat-4310	166	12	agents	agent	NOUN
easat-4310	166	13	,	,	PUNCT
easat-4310	166	14	could	could	AUX
easat-4310	166	15	confound	confound	VERB
easat-4310	166	16	citrulline	citrulline	NOUN
easat-4310	166	17	measurements	measurement	NOUN
easat-4310	166	18	[	[	X
easat-4310	166	19	11	11	NUM
easat-4310	166	20	]	]	PUNCT
easat-4310	166	21	.	.	PUNCT
easat-4310	167	1	additionally	additionally	ADV
easat-4310	167	2	,	,	PUNCT
easat-4310	167	3	systemic	systemic	ADJ
easat-4310	167	4	inflammation	inflammation	NOUN
easat-4310	167	5	,	,	PUNCT
easat-4310	167	6	driven	drive	VERB
easat-4310	167	7	by	by	ADP
easat-4310	167	8	chemotherapy	chemotherapy	NOUN
easat-4310	167	9	-	-	PUNCT
easat-4310	167	10	induced	induce	VERB
easat-4310	167	11	cytokine	cytokine	NOUN
easat-4310	167	12	release	release	NOUN
easat-4310	167	13	,	,	PUNCT
easat-4310	167	14	can	can	AUX
easat-4310	167	15	impact	impact	VERB
easat-4310	167	16	both	both	DET
easat-4310	167	17	intestinal	intestinal	ADJ
easat-4310	167	18	integrity	integrity	NOUN
easat-4310	167	19	and	and	CCONJ
easat-4310	167	20	metabolic	metabolic	NOUN
easat-4310	167	21	pathways	pathway	NOUN
easat-4310	167	22	involved	involve	VERB
easat-4310	167	23	in	in	ADP
easat-4310	167	24	citrulline	citrulline	NOUN
easat-4310	167	25	synthesis	synthesis	NOUN
easat-4310	167	26	[	[	X
easat-4310	167	27	15	15	NUM
easat-4310	167	28	]	]	PUNCT
easat-4310	167	29	.	.	PUNCT
easat-4310	168	1	these	these	DET
easat-4310	168	2	multifaceted	multifaceted	ADJ
easat-4310	168	3	influences	influence	NOUN
easat-4310	168	4	highlight	highlight	VERB
easat-4310	168	5	the	the	DET
easat-4310	168	6	need	need	NOUN
easat-4310	168	7	for	for	ADP
easat-4310	168	8	a	a	DET
easat-4310	168	9	more	more	ADV
easat-4310	168	10	comprehensive	comprehensive	ADJ
easat-4310	168	11	approach	approach	NOUN
easat-4310	168	12	to	to	ADP
easat-4310	168	13	citrulline	citrulline	NOUN
easat-4310	168	14	interpretation	interpretation	NOUN
easat-4310	168	15	.	.	PUNCT
easat-4310	169	1	future	future	ADJ
easat-4310	169	2	research	research	NOUN
easat-4310	169	3	should	should	AUX
easat-4310	169	4	focus	focus	VERB
easat-4310	169	5	on	on	ADP
easat-4310	169	6	integrating	integrate	VERB
easat-4310	169	7	citrulline	citrulline	NOUN
easat-4310	169	8	monitoring	monitoring	NOUN
easat-4310	169	9	with	with	ADP
easat-4310	169	10	broader	broad	ADJ
easat-4310	169	11	clinical	clinical	ADJ
easat-4310	169	12	and	and	CCONJ
easat-4310	169	13	biochemical	biochemical	ADJ
easat-4310	169	14	parameters	parameter	NOUN
easat-4310	169	15	,	,	PUNCT
easat-4310	169	16	enabling	enable	VERB
easat-4310	169	17	a	a	DET
easat-4310	169	18	more	more	ADV
easat-4310	169	19	accurate	accurate	ADJ
easat-4310	169	20	assessment	assessment	NOUN
easat-4310	169	21	of	of	ADP
easat-4310	169	22	its	its	PRON
easat-4310	169	23	diagnostic	diagnostic	ADJ
easat-4310	169	24	and	and	CCONJ
easat-4310	169	25	prognostic	prognostic	ADJ
easat-4310	169	26	value	value	NOUN
easat-4310	169	27	.	.	PUNCT
easat-4310	170	1	longitudinal	longitudinal	ADJ
easat-4310	170	2	studies	study	NOUN
easat-4310	170	3	with	with	ADP
easat-4310	170	4	larger	large	ADJ
easat-4310	170	5	,	,	PUNCT
easat-4310	170	6	ethnically	ethnically	ADV
easat-4310	170	7	diverse	diverse	ADJ
easat-4310	170	8	cohorts	cohort	NOUN
easat-4310	170	9	are	be	AUX
easat-4310	170	10	essential	essential	ADJ
easat-4310	170	11	to	to	PART
easat-4310	170	12	validate	validate	VERB
easat-4310	170	13	these	these	DET
easat-4310	170	14	findings	finding	NOUN
easat-4310	170	15	,	,	PUNCT
easat-4310	170	16	establish	establish	VERB
easat-4310	170	17	standardized	standardized	ADJ
easat-4310	170	18	thresholds	threshold	NOUN
easat-4310	170	19	,	,	PUNCT
easat-4310	170	20	and	and	CCONJ
easat-4310	170	21	refine	refine	VERB
easat-4310	170	22	the	the	DET
easat-4310	170	23	biomarker	biomarker	NOUN
easat-4310	170	24	's	's	PART
easat-4310	170	25	application	application	NOUN
easat-4310	170	26	in	in	ADP
easat-4310	170	27	diverse	diverse	ADJ
easat-4310	170	28	clinical	clinical	ADJ
easat-4310	170	29	settings	setting	NOUN
easat-4310	170	30	[	[	X
easat-4310	170	31	19	19	NUM
easat-4310	170	32	]	]	PUNCT
easat-4310	170	33	.	.	PUNCT
easat-4310	171	1	despite	despite	SCONJ
easat-4310	171	2	its	its	PRON
easat-4310	171	3	inherent	inherent	ADJ
easat-4310	171	4	limitations	limitation	NOUN
easat-4310	171	5	,	,	PUNCT
easat-4310	171	6	this	this	DET
easat-4310	171	7	study	study	NOUN
easat-4310	171	8	underscores	underscore	VERB
easat-4310	171	9	the	the	DET
easat-4310	171	10	promising	promising	ADJ
easat-4310	171	11	role	role	NOUN
easat-4310	171	12	of	of	ADP
easat-4310	171	13	citrulline	citrulline	NOUN
easat-4310	171	14	as	as	ADP
easat-4310	171	15	a	a	DET
easat-4310	171	16	biomarker	biomarker	NOUN
easat-4310	171	17	for	for	ADP
easat-4310	171	18	gastrointestinal	gastrointestinal	ADJ
easat-4310	171	19	mucositis	mucositis	NOUN
easat-4310	171	20	in	in	ADP
easat-4310	171	21	pediatric	pediatric	ADJ
easat-4310	171	22	oncology	oncology	NOUN
easat-4310	171	23	.	.	PUNCT
easat-4310	172	1	its	its	PRON
easat-4310	172	2	non	non	ADJ
easat-4310	172	3	-	-	ADJ
easat-4310	172	4	invasive	invasive	ADJ
easat-4310	172	5	procedure	procedure	NOUN
easat-4310	172	6	offers	offer	VERB
easat-4310	172	7	a	a	DET
easat-4310	172	8	significant	significant	ADJ
easat-4310	172	9	advantage	advantage	NOUN
easat-4310	172	10	over	over	ADP
easat-4310	172	11	traditional	traditional	ADJ
easat-4310	172	12	diagnostic	diagnostic	ADJ
easat-4310	172	13	methods	method	NOUN
easat-4310	172	14	like	like	ADP
easat-4310	172	15	intestinal	intestinal	ADJ
easat-4310	172	16	biopsy	biopsy	NOUN
easat-4310	172	17	,	,	PUNCT
easat-4310	172	18	which	which	PRON
easat-4310	172	19	are	be	AUX
easat-4310	172	20	impractical	impractical	ADJ
easat-4310	172	21	and	and	CCONJ
easat-4310	172	22	often	often	ADV
easat-4310	172	23	distressing	distressing	ADJ
easat-4310	172	24	for	for	ADP
easat-4310	172	25	young	young	ADJ
easat-4310	172	26	patients	patient	NOUN
easat-4310	172	27	[	[	X
easat-4310	172	28	12	12	NUM
easat-4310	172	29	]	]	PUNCT
easat-4310	172	30	.	.	PUNCT
easat-4310	173	1	by	by	ADP
easat-4310	173	2	reflecting	reflect	VERB
easat-4310	173	3	mucosal	mucosal	NOUN
easat-4310	173	4	integrity	integrity	NOUN
easat-4310	173	5	,	,	PUNCT
easat-4310	173	6	citrulline	citrulline	NOUN
easat-4310	173	7	serves	serve	VERB
easat-4310	173	8	as	as	ADP
easat-4310	173	9	a	a	DET
easat-4310	173	10	reliable	reliable	ADJ
easat-4310	173	11	indicator	indicator	NOUN
easat-4310	173	12	for	for	ADP
easat-4310	173	13	detecting	detect	VERB
easat-4310	173	14	early	early	ADJ
easat-4310	173	15	mucositis	mucositis	NOUN
easat-4310	173	16	and	and	CCONJ
easat-4310	173	17	assessing	assess	VERB
easat-4310	173	18	the	the	DET
easat-4310	173	19	severity	severity	NOUN
easat-4310	173	20	of	of	ADP
easat-4310	173	21	intestinal	intestinal	ADJ
easat-4310	173	22	injury	injury	NOUN
easat-4310	173	23	[	[	X
easat-4310	173	24	19	19	NUM
easat-4310	173	25	]	]	PUNCT
easat-4310	173	26	.	.	PUNCT
easat-4310	174	1	this	this	DET
easat-4310	174	2	biomarker	biomarker	NOUN
easat-4310	174	3	has	have	VERB
easat-4310	174	4	the	the	DET
easat-4310	174	5	potential	potential	NOUN
easat-4310	174	6	to	to	PART
easat-4310	174	7	transform	transform	VERB
easat-4310	174	8	supportive	supportive	ADJ
easat-4310	174	9	care	care	NOUN
easat-4310	174	10	strategies	strategy	NOUN
easat-4310	174	11	,	,	PUNCT
easat-4310	174	12	enabling	enable	VERB
easat-4310	174	13	timely	timely	ADJ
easat-4310	174	14	interventions	intervention	NOUN
easat-4310	174	15	to	to	PART
easat-4310	174	16	mitigate	mitigate	VERB
easat-4310	174	17	complications	complication	NOUN
easat-4310	174	18	and	and	CCONJ
easat-4310	174	19	maintain	maintain	VERB
easat-4310	174	20	the	the	DET
easat-4310	174	21	continuity	continuity	NOUN
easat-4310	174	22	of	of	ADP
easat-4310	174	23	chemotherapy	chemotherapy	NOUN
easat-4310	174	24	.	.	PUNCT
easat-4310	175	1	for	for	ADP
easat-4310	175	2	example	example	NOUN
easat-4310	175	3	,	,	PUNCT
easat-4310	175	4	integrating	integrate	VERB
easat-4310	175	5	citrulline	citrulline	NOUN
easat-4310	175	6	monitoring	monitoring	NOUN
easat-4310	175	7	into	into	ADP
easat-4310	175	8	routine	routine	ADJ
easat-4310	175	9	clinical	clinical	ADJ
easat-4310	175	10	practice	practice	NOUN
easat-4310	175	11	could	could	AUX
easat-4310	175	12	guide	guide	VERB
easat-4310	175	13	personalized	personalized	ADJ
easat-4310	175	14	nutrition	nutrition	NOUN
easat-4310	175	15	and	and	CCONJ
easat-4310	175	16	pharmacological	pharmacological	ADJ
easat-4310	175	17	support	support	NOUN
easat-4310	175	18	to	to	PART
easat-4310	175	19	enhance	enhance	VERB
easat-4310	175	20	mucosal	mucosal	NOUN
easat-4310	175	21	recovery	recovery	NOUN
easat-4310	176	1	[	[	X
easat-4310	176	2	27	27	NUM
easat-4310	176	3	]	]	PUNCT
easat-4310	176	4	.	.	PUNCT
easat-4310	177	1	furthermore	furthermore	ADV
easat-4310	177	2	,	,	PUNCT
easat-4310	177	3	its	its	PRON
easat-4310	177	4	use	use	NOUN
easat-4310	177	5	in	in	ADP
easat-4310	177	6	longitudinal	longitudinal	ADJ
easat-4310	177	7	studies	study	NOUN
easat-4310	177	8	could	could	AUX
easat-4310	177	9	help	help	AUX
easat-4310	177	10	identify	identify	VERB
easat-4310	177	11	patients	patient	NOUN
easat-4310	177	12	at	at	ADP
easat-4310	177	13	higher	high	ADJ
easat-4310	177	14	risk	risk	NOUN
easat-4310	177	15	for	for	ADP
easat-4310	177	16	severe	severe	ADJ
easat-4310	177	17	mucositis	mucositis	NOUN
easat-4310	177	18	,	,	PUNCT
easat-4310	177	19	facilitating	facilitate	VERB
easat-4310	177	20	early	early	ADJ
easat-4310	177	21	preventive	preventive	ADJ
easat-4310	177	22	measures	measure	NOUN
easat-4310	177	23	[	[	X
easat-4310	177	24	11	11	NUM
easat-4310	177	25	]	]	PUNCT
easat-4310	177	26	.	.	PUNCT
easat-4310	178	1	future	future	ADJ
easat-4310	178	2	research	research	NOUN
easat-4310	178	3	should	should	AUX
easat-4310	178	4	focus	focus	VERB
easat-4310	178	5	on	on	ADP
easat-4310	178	6	validating	validate	VERB
easat-4310	178	7	citrulline	citrulline	NOUN
easat-4310	178	8	thresholds	threshold	NOUN
easat-4310	178	9	in	in	ADP
easat-4310	178	10	diverse	diverse	ADJ
easat-4310	178	11	pediatric	pediatric	ADJ
easat-4310	178	12	populations	population	NOUN
easat-4310	178	13	and	and	CCONJ
easat-4310	178	14	exploring	explore	VERB
easat-4310	178	15	its	its	PRON
easat-4310	178	16	integration	integration	NOUN
easat-4310	178	17	with	with	ADP
easat-4310	178	18	other	other	ADJ
easat-4310	178	19	biomarkers	biomarker	NOUN
easat-4310	178	20	to	to	PART
easat-4310	178	21	improve	improve	VERB
easat-4310	178	22	diagnostic	diagnostic	ADJ
easat-4310	178	23	accuracy	accuracy	NOUN
easat-4310	178	24	.	.	PUNCT
easat-4310	179	1	additionally	additionally	ADV
easat-4310	179	2	,	,	PUNCT
easat-4310	179	3	understanding	understand	VERB
easat-4310	179	4	the	the	DET
easat-4310	179	5	temporal	temporal	ADJ
easat-4310	179	6	dynamics	dynamic	NOUN
easat-4310	179	7	of	of	ADP
easat-4310	179	8	citrulline	citrulline	NOUN
easat-4310	179	9	during	during	ADP
easat-4310	179	10	mucositis	mucositis	NOUN
easat-4310	179	11	recovery	recovery	NOUN
easat-4310	179	12	could	could	AUX
easat-4310	179	13	inform	inform	VERB
easat-4310	179	14	better	well	ADJ
easat-4310	179	15	timing	timing	NOUN
easat-4310	179	16	for	for	ADP
easat-4310	179	17	clinical	clinical	ADJ
easat-4310	179	18	interventions	intervention	NOUN
easat-4310	179	19	,	,	PUNCT
easat-4310	179	20	ultimately	ultimately	ADV
easat-4310	179	21	enhancing	enhance	VERB
easat-4310	179	22	outcomes	outcome	NOUN
easat-4310	179	23	for	for	ADP
easat-4310	179	24	pediatric	pediatric	ADJ
easat-4310	179	25	cancer	cancer	NOUN
easat-4310	179	26	patients	patient	NOUN
easat-4310	179	27	worldwide	worldwide	ADV
easat-4310	180	1	[	[	X
easat-4310	180	2	17	17	NUM
easat-4310	180	3	]	]	SYM
easat-4310	180	4	.	.	PUNCT
easat-4310	181	1	5	5	X
easat-4310	181	2	.	.	X
easat-4310	181	3	conclusions	conclusion	NOUN
easat-4310	181	4	this	this	DET
easat-4310	181	5	study	study	NOUN
easat-4310	181	6	underscores	underscore	VERB
easat-4310	181	7	citrulline	citrulline	NOUN
easat-4310	181	8	's	's	PART
easat-4310	181	9	potential	potential	NOUN
easat-4310	181	10	as	as	ADP
easat-4310	181	11	a	a	DET
easat-4310	181	12	non	non	ADJ
easat-4310	181	13	-	-	ADJ
easat-4310	181	14	invasive	invasive	ADJ
easat-4310	181	15	biomarker	biomarker	NOUN
easat-4310	181	16	for	for	ADP
easat-4310	181	17	gastrointestinal	gastrointestinal	ADJ
easat-4310	181	18	mucositis	mucositis	NOUN
easat-4310	181	19	in	in	ADP
easat-4310	181	20	pediatric	pediatric	ADJ
easat-4310	181	21	oncology	oncology	NOUN
easat-4310	181	22	.	.	PUNCT
easat-4310	182	1	its	its	PRON
easat-4310	182	2	levels	level	NOUN
easat-4310	182	3	reflect	reflect	VERB
easat-4310	182	4	mucosal	mucosal	NOUN
easat-4310	182	5	integrity	integrity	NOUN
easat-4310	182	6	and	and	CCONJ
easat-4310	182	7	dynamic	dynamic	ADJ
easat-4310	182	8	recovery	recovery	NOUN
easat-4310	182	9	,	,	PUNCT
easat-4310	182	10	offering	offer	VERB
easat-4310	182	11	advantages	advantage	NOUN
easat-4310	182	12	over	over	ADP
easat-4310	182	13	invasive	invasive	ADJ
easat-4310	182	14	diagnostics	diagnostic	NOUN
easat-4310	182	15	.	.	PUNCT
easat-4310	183	1	the	the	DET
easat-4310	183	2	findings	finding	NOUN
easat-4310	183	3	highlight	highlight	VERB
easat-4310	183	4	its	its	PRON
easat-4310	183	5	role	role	NOUN
easat-4310	183	6	in	in	ADP
easat-4310	183	7	monitoring	monitor	VERB
easat-4310	183	8	chemotherapy1084	chemotherapy1084	PROPN
easat-4310	183	9	edelweiss	edelweiss	PROPN
easat-4310	183	10	applied	apply	VERB
easat-4310	183	11	science	science	NOUN
easat-4310	183	12	and	and	CCONJ
easat-4310	183	13	technology	technology	NOUN
easat-4310	183	14	issn	issn	PROPN
easat-4310	183	15	:	:	PUNCT
easat-4310	183	16	2576	2576	NUM
easat-4310	183	17	-	-	SYM
easat-4310	183	18	8484	8484	NUM
easat-4310	183	19	vol	vol	NOUN
easat-4310	183	20	.	.	PROPN
easat-4310	184	1	9	9	NUM
easat-4310	184	2	,	,	PUNCT
easat-4310	184	3	no	no	INTJ
easat-4310	184	4	.	.	NOUN
easat-4310	184	5	1	1	NUM
easat-4310	184	6	:	:	SYM
easat-4310	184	7	1078	1078	NUM
easat-4310	184	8	-	-	SYM
easat-4310	184	9	1085	1085	NUM
easat-4310	184	10	,	,	PUNCT
easat-4310	184	11	2025	2025	NUM
easat-4310	184	12	doi	doi	NOUN
easat-4310	184	13	:	:	PUNCT
easat-4310	184	14	10.55214/25768484.v9i1.4310	10.55214/25768484.v9i1.4310	NUM
easat-4310	184	15	©	©	PROPN
easat-4310	184	16	2025	2025	NUM
easat-4310	184	17	by	by	ADP
easat-4310	184	18	the	the	DET
easat-4310	184	19	authors	author	NOUN
easat-4310	184	20	;	;	PUNCT
easat-4310	184	21	licensee	licensee	PROPN
easat-4310	184	22	learning	learning	NOUN
easat-4310	184	23	gate	gate	NOUN
easat-4310	184	24	induced	induce	VERB
easat-4310	184	25	injury	injury	NOUN
easat-4310	184	26	,	,	PUNCT
easat-4310	184	27	guiding	guide	VERB
easat-4310	184	28	personalized	personalized	ADJ
easat-4310	184	29	interventions	intervention	NOUN
easat-4310	184	30	,	,	PUNCT
easat-4310	184	31	and	and	CCONJ
easat-4310	184	32	improving	improve	VERB
easat-4310	184	33	supportive	supportive	ADJ
easat-4310	184	34	care	care	NOUN
easat-4310	184	35	strategies	strategy	NOUN
easat-4310	184	36	.	.	PUNCT
easat-4310	185	1	further	further	ADJ
easat-4310	185	2	validation	validation	NOUN
easat-4310	185	3	in	in	ADP
easat-4310	185	4	diverse	diverse	ADJ
easat-4310	185	5	populations	population	NOUN
easat-4310	185	6	is	be	AUX
easat-4310	185	7	essential	essential	ADJ
easat-4310	185	8	to	to	PART
easat-4310	185	9	optimize	optimize	VERB
easat-4310	185	10	its	its	PRON
easat-4310	185	11	clinical	clinical	ADJ
easat-4310	185	12	utility	utility	NOUN
easat-4310	185	13	and	and	CCONJ
easat-4310	185	14	establish	establish	VERB
easat-4310	185	15	standardized	standardized	ADJ
easat-4310	185	16	thresholds	threshold	NOUN
easat-4310	185	17	for	for	ADP
easat-4310	185	18	decision	decision	NOUN
easat-4310	185	19	-	-	PUNCT
easat-4310	185	20	making	making	NOUN
easat-4310	185	21	.	.	PUNCT
easat-4310	186	1	fundings	funding	NOUN
easat-4310	186	2	:	:	PUNCT
easat-4310	186	3	this	this	DET
easat-4310	186	4	study	study	NOUN
easat-4310	186	5	was	be	AUX
easat-4310	186	6	conducted	conduct	VERB
easat-4310	186	7	in	in	ADP
easat-4310	186	8	accordance	accordance	NOUN
easat-4310	186	9	with	with	ADP
easat-4310	186	10	the	the	DET
easat-4310	186	11	ethical	ethical	ADJ
easat-4310	186	12	standards	standard	NOUN
easat-4310	186	13	outlined	outline	VERB
easat-4310	186	14	in	in	ADP
easat-4310	186	15	the	the	DET
easat-4310	186	16	declaration	declaration	NOUN
easat-4310	186	17	of	of	ADP
easat-4310	186	18	helsinki	helsinki	PROPN
easat-4310	186	19	.	.	PUNCT
easat-4310	187	1	ethical	ethical	ADJ
easat-4310	187	2	approval	approval	NOUN
easat-4310	187	3	was	be	AUX
easat-4310	187	4	obtained	obtain	VERB
easat-4310	187	5	from	from	ADP
easat-4310	187	6	the	the	DET
easat-4310	187	7	institutional	institutional	ADJ
easat-4310	187	8	review	review	PROPN
easat-4310	187	9	board	board	PROPN
easat-4310	187	10	of	of	ADP
easat-4310	187	11	dr	dr	PROPN
easat-4310	187	12	.	.	PROPN
easat-4310	187	13	soetomo	soetomo	PROPN
easat-4310	187	14	general	general	PROPN
easat-4310	187	15	hospital	hospital	PROPN
easat-4310	187	16	,	,	PUNCT
easat-4310	187	17	indonesia	indonesia	PROPN
easat-4310	187	18	.	.	PUNCT
easat-4310	188	1	informed	informed	ADJ
easat-4310	188	2	consent	consent	NOUN
easat-4310	188	3	was	be	AUX
easat-4310	188	4	obtained	obtain	VERB
easat-4310	188	5	from	from	ADP
easat-4310	188	6	all	all	DET
easat-4310	188	7	participants	participant	NOUN
easat-4310	188	8	or	or	CCONJ
easat-4310	188	9	their	their	PRON
easat-4310	188	10	legal	legal	ADJ
easat-4310	188	11	guardians	guardian	NOUN
easat-4310	188	12	prior	prior	ADV
easat-4310	188	13	to	to	ADP
easat-4310	188	14	inclusion	inclusion	NOUN
easat-4310	188	15	in	in	ADP
easat-4310	188	16	the	the	DET
easat-4310	188	17	study	study	NOUN
easat-4310	188	18	.	.	PUNCT
easat-4310	189	1	approval	approval	NOUN
easat-4310	189	2	reference	reference	NOUN
easat-4310	189	3	number	number	NOUN
easat-4310	189	4	:	:	PUNCT
easat-4310	189	5	0696	0696	NUM
easat-4310	189	6	/	/	SYM
easat-4310	189	7	kepk	kepk	NOUN
easat-4310	189	8	/	/	SYM
easat-4310	189	9	v1/2023	v1/2023	NOUN
easat-4310	189	10	.	.	PUNCT
easat-4310	190	1	transparency	transparency	NOUN
easat-4310	190	2	:	:	PUNCT
easat-4310	190	3	the	the	DET
easat-4310	190	4	authors	author	NOUN
easat-4310	190	5	confirm	confirm	VERB
easat-4310	190	6	that	that	SCONJ
easat-4310	190	7	the	the	DET
easat-4310	190	8	manuscript	manuscript	NOUN
easat-4310	190	9	is	be	AUX
easat-4310	190	10	an	an	DET
easat-4310	190	11	honest	honest	ADJ
easat-4310	190	12	,	,	PUNCT
easat-4310	190	13	accurate	accurate	ADJ
easat-4310	190	14	,	,	PUNCT
easat-4310	190	15	and	and	CCONJ
easat-4310	190	16	transparent	transparent	ADJ
easat-4310	190	17	account	account	NOUN
easat-4310	190	18	of	of	ADP
easat-4310	190	19	the	the	DET
easat-4310	190	20	study	study	NOUN
easat-4310	190	21	;	;	PUNCT
easat-4310	190	22	that	that	SCONJ
easat-4310	190	23	no	no	DET
easat-4310	190	24	vital	vital	ADJ
easat-4310	190	25	features	feature	NOUN
easat-4310	190	26	of	of	ADP
easat-4310	190	27	the	the	DET
easat-4310	190	28	study	study	NOUN
easat-4310	190	29	have	have	AUX
easat-4310	190	30	been	be	AUX
easat-4310	190	31	omitted	omit	VERB
easat-4310	190	32	;	;	PUNCT
easat-4310	190	33	and	and	CCONJ
easat-4310	190	34	that	that	SCONJ
easat-4310	190	35	any	any	DET
easat-4310	190	36	discrepancies	discrepancy	NOUN
easat-4310	190	37	from	from	ADP
easat-4310	190	38	the	the	DET
easat-4310	190	39	study	study	NOUN
easat-4310	190	40	as	as	SCONJ
easat-4310	190	41	planned	plan	VERB
easat-4310	190	42	have	have	AUX
easat-4310	190	43	been	be	AUX
easat-4310	190	44	explained	explain	VERB
easat-4310	190	45	.	.	PUNCT
easat-4310	191	1	this	this	DET
easat-4310	191	2	study	study	NOUN
easat-4310	191	3	followed	follow	VERB
easat-4310	191	4	all	all	DET
easat-4310	191	5	ethical	ethical	ADJ
easat-4310	191	6	practices	practice	NOUN
easat-4310	191	7	during	during	ADP
easat-4310	191	8	writing	writing	NOUN
easat-4310	191	9	.	.	PUNCT
easat-4310	192	1	acknowledgements	acknowledgement	NOUN
easat-4310	192	2	:	:	PUNCT
easat-4310	192	3	the	the	DET
easat-4310	192	4	authors	author	NOUN
easat-4310	192	5	would	would	AUX
easat-4310	192	6	like	like	VERB
easat-4310	192	7	to	to	PART
easat-4310	192	8	thank	thank	VERB
easat-4310	192	9	the	the	DET
easat-4310	192	10	patients	patient	NOUN
easat-4310	192	11	and	and	CCONJ
easat-4310	192	12	their	their	PRON
easat-4310	192	13	families	family	NOUN
easat-4310	192	14	for	for	ADP
easat-4310	192	15	their	their	PRON
easat-4310	192	16	participation	participation	NOUN
easat-4310	192	17	in	in	ADP
easat-4310	192	18	this	this	DET
easat-4310	192	19	study	study	NOUN
easat-4310	192	20	.	.	PUNCT
easat-4310	193	1	we	we	PRON
easat-4310	193	2	also	also	ADV
easat-4310	193	3	extend	extend	VERB
easat-4310	193	4	our	our	PRON
easat-4310	193	5	gratitude	gratitude	NOUN
easat-4310	193	6	to	to	ADP
easat-4310	193	7	the	the	DET
easat-4310	193	8	medical	medical	ADJ
easat-4310	193	9	staff	staff	NOUN
easat-4310	193	10	and	and	CCONJ
easat-4310	193	11	research	research	NOUN
easat-4310	193	12	team	team	NOUN
easat-4310	193	13	at	at	ADP
easat-4310	193	14	dr	dr	PROPN
easat-4310	193	15	.	.	PROPN
easat-4310	193	16	soetomo	soetomo	PROPN
easat-4310	193	17	general	general	PROPN
easat-4310	193	18	hospital	hospital	NOUN
easat-4310	193	19	for	for	ADP
easat-4310	193	20	their	their	PRON
easat-4310	193	21	invaluable	invaluable	ADJ
easat-4310	193	22	support	support	NOUN
easat-4310	193	23	during	during	ADP
easat-4310	193	24	data	data	NOUN
easat-4310	193	25	collection	collection	NOUN
easat-4310	193	26	and	and	CCONJ
easat-4310	193	27	analysis	analysis	NOUN
easat-4310	193	28	.	.	PUNCT
easat-4310	194	1	special	special	ADJ
easat-4310	194	2	thanks	thank	NOUN
easat-4310	194	3	to	to	ADP
easat-4310	194	4	the	the	DET
easat-4310	194	5	institutional	institutional	ADJ
easat-4310	194	6	review	review	NOUN
easat-4310	194	7	board	board	NOUN
easat-4310	194	8	for	for	ADP
easat-4310	194	9	their	their	PRON
easat-4310	194	10	guidance	guidance	NOUN
easat-4310	194	11	and	and	CCONJ
easat-4310	194	12	approval	approval	NOUN
easat-4310	194	13	,	,	PUNCT
easat-4310	194	14	ensuring	ensure	VERB
easat-4310	194	15	the	the	DET
easat-4310	194	16	ethical	ethical	ADJ
easat-4310	194	17	conduct	conduct	NOUN
easat-4310	194	18	of	of	ADP
easat-4310	194	19	this	this	DET
easat-4310	194	20	research	research	NOUN
easat-4310	194	21	.	.	PUNCT
easat-4310	195	1	copyright	copyright	NOUN
easat-4310	195	2	:	:	PUNCT
easat-4310	195	3	©	©	PROPN
easat-4310	195	4	2025	2025	NUM
easat-4310	195	5	by	by	ADP
easat-4310	195	6	the	the	DET
easat-4310	195	7	authors	author	NOUN
easat-4310	195	8	.	.	PUNCT
easat-4310	196	1	this	this	DET
easat-4310	196	2	open	open	ADJ
easat-4310	196	3	-	-	PUNCT
easat-4310	196	4	access	access	NOUN
easat-4310	196	5	article	article	NOUN
easat-4310	196	6	is	be	AUX
easat-4310	196	7	distributed	distribute	VERB
easat-4310	196	8	under	under	ADP
easat-4310	196	9	the	the	DET
easat-4310	196	10	terms	term	NOUN
easat-4310	196	11	and	and	CCONJ
easat-4310	196	12	conditions	condition	NOUN
easat-4310	196	13	of	of	ADP
easat-4310	196	14	the	the	DET
easat-4310	196	15	creative	creative	ADJ
easat-4310	196	16	commons	common	NOUN
easat-4310	196	17	attribution	attribution	NOUN
easat-4310	196	18	(	(	PUNCT
easat-4310	196	19	cc	cc	NOUN
easat-4310	196	20	by	by	ADP
easat-4310	196	21	)	)	PUNCT
easat-4310	196	22	license	license	NOUN
easat-4310	196	23	(	(	PUNCT
easat-4310	196	24	https://creativecommons.org/licenses/by/4.0/	https://creativecommons.org/licenses/by/4.0/	PROPN
easat-4310	196	25	)	)	PUNCT
easat-4310	196	26	.	.	PUNCT
easat-4310	197	1	abbreviations	abbreviation	NOUN
easat-4310	197	2	:	:	PUNCT
easat-4310	197	3	all	all	PRON
easat-4310	197	4	:	:	PUNCT
easat-4310	197	5	acute	acute	ADJ
easat-4310	197	6	lymphoblastic	lymphoblastic	ADJ
easat-4310	197	7	leukemia	leukemia	NOUN
easat-4310	197	8	.	.	PUNCT
easat-4310	198	1	hd	hd	NOUN
easat-4310	198	2	-	-	PUNCT
easat-4310	198	3	mtx	mtx	NOUN
easat-4310	198	4	:	:	PUNCT
easat-4310	198	5	high	high	ADJ
easat-4310	198	6	-	-	PUNCT
easat-4310	198	7	dose	dose	NOUN
easat-4310	198	8	methotrexate	methotrexate	NOUN
easat-4310	198	9	.	.	PUNCT
easat-4310	199	1	gi	gi	NOUN
easat-4310	199	2	:	:	PUNCT
easat-4310	200	1	gastrointestinal	gastrointestinal	ADJ
easat-4310	200	2	.	.	PUNCT
easat-4310	201	1	sr	sr	PROPN
easat-4310	201	2	:	:	PUNCT
easat-4310	201	3	standard	standard	ADJ
easat-4310	201	4	risk	risk	NOUN
easat-4310	201	5	.	.	PUNCT
easat-4310	202	1	hr	hr	NOUN
easat-4310	202	2	:	:	PUNCT
easat-4310	202	3	high	high	ADJ
easat-4310	202	4	risk	risk	NOUN
easat-4310	202	5	.	.	PUNCT
easat-4310	203	1	hplc	hplc	NOUN
easat-4310	203	2	:	:	PUNCT
easat-4310	203	3	high	high	ADJ
easat-4310	203	4	-	-	PUNCT
easat-4310	203	5	performance	performance	NOUN
easat-4310	203	6	liquid	liquid	ADJ
easat-4310	203	7	chromatography	chromatography	NOUN
easat-4310	203	8	.	.	PUNCT
easat-4310	204	1	nci	nci	PROPN
easat-4310	204	2	:	:	PUNCT
easat-4310	205	1	national	national	PROPN
easat-4310	205	2	cancer	cancer	PROPN
easat-4310	205	3	institute	institute	PROPN
easat-4310	205	4	.	.	PUNCT
easat-4310	206	1	tnf	tnf	PROPN
easat-4310	206	2	-	-	PUNCT
easat-4310	206	3	α	α	PROPN
easat-4310	206	4	:	:	PUNCT
easat-4310	206	5	tumor	tumor	NOUN
easat-4310	206	6	necrosis	necrosis	NOUN
easat-4310	206	7	factor	factor	NOUN
easat-4310	206	8	-	-	PUNCT
easat-4310	206	9	alpha	alpha	NOUN
easat-4310	206	10	.	.	PUNCT
easat-4310	207	1	il	il	PROPN
easat-4310	207	2	:	:	PUNCT
easat-4310	207	3	interleukin	interleukin	NOUN
easat-4310	207	4	.	.	PUNCT
easat-4310	208	1	references	reference	NOUN
easat-4310	208	2	[	[	X
easat-4310	208	3	1	1	NUM
easat-4310	208	4	]	]	PUNCT
easat-4310	208	5	m.	m.	NOUN
easat-4310	208	6	pauly	pauly	PROPN
easat-4310	208	7	and	and	CCONJ
easat-4310	208	8	l.	l.	PROPN
easat-4310	208	9	b.	b.	PROPN
easat-4310	208	10	silverman	silverman	PROPN
easat-4310	208	11	,	,	PUNCT
easat-4310	208	12	"	"	PUNCT
easat-4310	208	13	diagnosis	diagnosis	NOUN
easat-4310	208	14	and	and	CCONJ
easat-4310	208	15	treatment	treatment	NOUN
easat-4310	208	16	of	of	ADP
easat-4310	208	17	childhood	childhood	NOUN
easat-4310	208	18	acute	acute	NOUN
easat-4310	208	19	lymphoblastic	lymphoblastic	ADJ
easat-4310	208	20	leukemia	leukemia	NOUN
easat-4310	208	21	,	,	PUNCT
easat-4310	208	22	"	"	PUNCT
easat-4310	208	23	neoplastic	neoplastic	ADJ
easat-4310	208	24	diseases	disease	NOUN
easat-4310	208	25	of	of	ADP
easat-4310	208	26	the	the	DET
easat-4310	208	27	blood	blood	NOUN
easat-4310	208	28	,	,	PUNCT
easat-4310	208	29	pp	pp	ADP
easat-4310	208	30	.	.	PUNCT
easat-4310	209	1	307	307	NUM
easat-4310	209	2	-	-	SYM
easat-4310	209	3	335	335	NUM
easat-4310	209	4	,	,	PUNCT
easat-4310	209	5	2018	2018	NUM
easat-4310	209	6	.	.	PUNCT
easat-4310	210	1	https://doi.org/10.1385/1-59259-307-0:87	https://doi.org/10.1385/1-59259-307-0:87	NOUN
easat-4310	210	2	[	[	SYM
easat-4310	210	3	2	2	NUM
easat-4310	210	4	]	]	PUNCT
easat-4310	210	5	r.	r.	PROPN
easat-4310	210	6	santiago	santiago	PROPN
easat-4310	210	7	and	and	CCONJ
easat-4310	210	8	t.	t.	PROPN
easat-4310	210	9	h.	h.	PROPN
easat-4310	210	10	tran	tran	PROPN
easat-4310	210	11	,	,	PUNCT
easat-4310	210	12	"	"	PUNCT
easat-4310	210	13	genomics	genomics	NOUN
easat-4310	210	14	and	and	CCONJ
easat-4310	210	15	precision	precision	NOUN
easat-4310	210	16	medicine	medicine	NOUN
easat-4310	210	17	in	in	ADP
easat-4310	210	18	pediatric	pediatric	ADJ
easat-4310	210	19	acute	acute	ADJ
easat-4310	210	20	lymphoblastic	lymphoblastic	ADJ
easat-4310	210	21	leukemia	leukemia	NOUN
easat-4310	210	22	,	,	PUNCT
easat-4310	210	23	"	"	PUNCT
easat-4310	210	24	journal	journal	NOUN
easat-4310	210	25	of	of	ADP
easat-4310	210	26	translational	translational	ADJ
easat-4310	210	27	genetics	genetic	NOUN
easat-4310	210	28	and	and	CCONJ
easat-4310	210	29	genomics	genomics	NOUN
easat-4310	210	30	,	,	PUNCT
easat-4310	210	31	vol	vol	NOUN
easat-4310	210	32	.	.	PROPN
easat-4310	210	33	5	5	NUM
easat-4310	210	34	,	,	PUNCT
easat-4310	210	35	no	no	INTJ
easat-4310	210	36	.	.	NOUN
easat-4310	210	37	4	4	NUM
easat-4310	210	38	,	,	PUNCT
easat-4310	210	39	pp	pp	ADJ
easat-4310	210	40	.	.	PUNCT
easat-4310	211	1	380	380	NUM
easat-4310	211	2	-	-	SYM
easat-4310	211	3	395	395	NUM
easat-4310	211	4	,	,	PUNCT
easat-4310	211	5	2021	2021	NUM
easat-4310	211	6	.	.	PUNCT
easat-4310	212	1	https://doi.org/10.20517/jtgg.2021.16	https://doi.org/10.20517/jtgg.2021.16	PROPN
easat-4310	213	1	[	[	X
easat-4310	213	2	3	3	NUM
easat-4310	213	3	]	]	X
easat-4310	213	4	p.	p.	NOUN
easat-4310	213	5	brown	brown	PROPN
easat-4310	213	6	et	et	PROPN
easat-4310	213	7	al	al	PROPN
easat-4310	213	8	.	.	PROPN
easat-4310	213	9	,	,	PUNCT
easat-4310	213	10	"	"	PUNCT
easat-4310	213	11	pediatric	pediatric	ADJ
easat-4310	213	12	acute	acute	ADJ
easat-4310	213	13	lymphoblastic	lymphoblastic	ADJ
easat-4310	213	14	leukemia	leukemia	NOUN
easat-4310	213	15	,	,	PUNCT
easat-4310	213	16	version	version	NOUN
easat-4310	213	17	2.2020	2.2020	NUM
easat-4310	213	18	,	,	PUNCT
easat-4310	213	19	nccn	nccn	ADJ
easat-4310	213	20	clinical	clinical	ADJ
easat-4310	213	21	practice	practice	NOUN
easat-4310	213	22	guidelines	guideline	NOUN
easat-4310	213	23	in	in	ADP
easat-4310	213	24	oncology	oncology	NOUN
easat-4310	213	25	,	,	PUNCT
easat-4310	213	26	"	"	PUNCT
easat-4310	213	27	journal	journal	NOUN
easat-4310	213	28	of	of	ADP
easat-4310	213	29	the	the	DET
easat-4310	213	30	national	national	ADJ
easat-4310	213	31	comprehensive	comprehensive	ADJ
easat-4310	213	32	cancer	cancer	NOUN
easat-4310	213	33	network	network	NOUN
easat-4310	213	34	,	,	PUNCT
easat-4310	213	35	vol	vol	NOUN
easat-4310	213	36	.	.	PROPN
easat-4310	213	37	18	18	NUM
easat-4310	213	38	,	,	PUNCT
easat-4310	213	39	no	no	INTJ
easat-4310	213	40	.	.	NOUN
easat-4310	213	41	1	1	NUM
easat-4310	213	42	,	,	PUNCT
easat-4310	213	43	pp	pp	ADJ
easat-4310	213	44	.	.	PUNCT
easat-4310	214	1	81	81	NUM
easat-4310	214	2	-	-	SYM
easat-4310	214	3	112	112	NUM
easat-4310	214	4	,	,	PUNCT
easat-4310	214	5	2020	2020	NUM
easat-4310	214	6	.	.	PUNCT
easat-4310	215	1	[	[	X
easat-4310	215	2	4	4	X
easat-4310	215	3	]	]	PUNCT
easat-4310	215	4	s.	s.	PROPN
easat-4310	215	5	elitzur	elitzur	PROPN
easat-4310	215	6	and	and	CCONJ
easat-4310	215	7	s.	s.	PROPN
easat-4310	215	8	izraeli	izraeli	PROPN
easat-4310	215	9	,	,	PUNCT
easat-4310	215	10	"	"	PUNCT
easat-4310	215	11	pediatric	pediatric	ADJ
easat-4310	215	12	acute	acute	ADJ
easat-4310	215	13	lymphoblastic	lymphoblastic	ADJ
easat-4310	215	14	leukemia	leukemia	NOUN
easat-4310	215	15	,	,	PUNCT
easat-4310	215	16	"	"	PUNCT
easat-4310	215	17	harefuah	harefuah	NOUN
easat-4310	215	18	,	,	PUNCT
easat-4310	215	19	vol	vol	NOUN
easat-4310	215	20	.	.	PROPN
easat-4310	215	21	162	162	NUM
easat-4310	215	22	,	,	PUNCT
easat-4310	215	23	no	no	INTJ
easat-4310	215	24	.	.	NOUN
easat-4310	215	25	1	1	NUM
easat-4310	215	26	,	,	PUNCT
easat-4310	215	27	pp	pp	ADJ
easat-4310	215	28	.	.	PUNCT
easat-4310	216	1	57	57	NUM
easat-4310	216	2	-	-	SYM
easat-4310	216	3	63	63	NUM
easat-4310	216	4	,	,	PUNCT
easat-4310	216	5	2023	2023	NUM
easat-4310	216	6	.	.	PUNCT
easat-4310	217	1	[	[	X
easat-4310	217	2	5	5	NUM
easat-4310	217	3	]	]	PUNCT
easat-4310	217	4	a.	a.	NOUN
easat-4310	217	5	m.	m.	NOUN
easat-4310	217	6	nguyen	nguyen	PROPN
easat-4310	217	7	et	et	PROPN
easat-4310	217	8	al	al	PROPN
easat-4310	217	9	.	.	PROPN
easat-4310	217	10	,	,	PUNCT
easat-4310	217	11	"	"	PUNCT
easat-4310	217	12	molecular	molecular	ADJ
easat-4310	217	13	cytogenetic	cytogenetic	ADJ
easat-4310	217	14	characterization	characterization	NOUN
easat-4310	217	15	of	of	ADP
easat-4310	217	16	a	a	DET
easat-4310	217	17	complex	complex	ADJ
easat-4310	217	18	karyotype	karyotype	NOUN
easat-4310	217	19	of	of	ADP
easat-4310	217	20	a	a	DET
easat-4310	217	21	pediatric	pediatric	ADJ
easat-4310	217	22	male	male	NOUN
easat-4310	217	23	patient	patient	NOUN
easat-4310	217	24	with	with	ADP
easat-4310	217	25	b	b	ADJ
easat-4310	217	26	-	-	PUNCT
easat-4310	217	27	acute	acute	ADJ
easat-4310	217	28	lymphoblastic	lymphoblastic	ADJ
easat-4310	217	29	leukemia	leukemia	NOUN
easat-4310	217	30	,	,	PUNCT
easat-4310	217	31	"	"	PUNCT
easat-4310	217	32	journal	journal	NOUN
easat-4310	217	33	of	of	ADP
easat-4310	217	34	the	the	DET
easat-4310	217	35	association	association	NOUN
easat-4310	217	36	of	of	ADP
easat-4310	217	37	genetic	genetic	ADJ
easat-4310	217	38	technologists	technologist	NOUN
easat-4310	217	39	,	,	PUNCT
easat-4310	217	40	vol	vol	NOUN
easat-4310	217	41	.	.	PROPN
easat-4310	217	42	46	46	NUM
easat-4310	217	43	,	,	PUNCT
easat-4310	217	44	no	no	INTJ
easat-4310	217	45	.	.	NOUN
easat-4310	217	46	1	1	NUM
easat-4310	217	47	,	,	PUNCT
easat-4310	217	48	2020	2020	NUM
easat-4310	217	49	.	.	PUNCT
easat-4310	218	1	[	[	X
easat-4310	218	2	6	6	NUM
easat-4310	218	3	]	]	PUNCT
easat-4310	218	4	e.	e.	PROPN
easat-4310	218	5	r.	r.	PROPN
easat-4310	218	6	abdelkhalek	abdelkhalek	PROPN
easat-4310	218	7	,	,	PUNCT
easat-4310	218	8	y.	y.	PROPN
easat-4310	218	9	e.-s	e.-s	PROPN
easat-4310	218	10	.	.	PUNCT
easat-4310	219	1	abo	abo	NOUN
easat-4310	219	2	-	-	PUNCT
easat-4310	219	3	elmagd	elmagd	NOUN
easat-4310	219	4	,	,	PUNCT
easat-4310	219	5	a.	a.	PROPN
easat-4310	219	6	s.	s.	PROPN
easat-4310	219	7	ahmed	ahmed	PROPN
easat-4310	219	8	,	,	PUNCT
easat-4310	219	9	and	and	CCONJ
easat-4310	219	10	m.	m.	NOUN
easat-4310	219	11	m.	m.	PROPN
easat-4310	219	12	arafa	arafa	PROPN
easat-4310	219	13	,	,	PUNCT
easat-4310	219	14	"	"	PUNCT
easat-4310	219	15	evaluation	evaluation	NOUN
easat-4310	219	16	of	of	ADP
easat-4310	219	17	antioxidants	antioxidant	NOUN
easat-4310	219	18	status	status	NOUN
easat-4310	219	19	at	at	ADP
easat-4310	219	20	diagnosis	diagnosis	NOUN
easat-4310	219	21	in	in	ADP
easat-4310	219	22	childhood	childhood	NOUN
easat-4310	219	23	acute	acute	NOUN
easat-4310	219	24	lymphoblastic	lymphoblastic	ADJ
easat-4310	219	25	leukemia	leukemia	NOUN
easat-4310	219	26	,	,	PUNCT
easat-4310	219	27	"	"	PUNCT
easat-4310	219	28	the	the	DET
easat-4310	219	29	egyptian	egyptian	ADJ
easat-4310	219	30	journal	journal	PROPN
easat-4310	219	31	of	of	ADP
easat-4310	219	32	hospital	hospital	NOUN
easat-4310	219	33	medicine	medicine	NOUN
easat-4310	219	34	,	,	PUNCT
easat-4310	219	35	vol	vol	NOUN
easat-4310	219	36	.	.	PROPN
easat-4310	219	37	85	85	NUM
easat-4310	219	38	,	,	PUNCT
easat-4310	219	39	no	no	INTJ
easat-4310	219	40	.	.	NOUN
easat-4310	219	41	2	2	NUM
easat-4310	219	42	,	,	PUNCT
easat-4310	219	43	pp	pp	ADJ
easat-4310	219	44	.	.	PUNCT
easat-4310	220	1	3724	3724	NUM
easat-4310	220	2	-	-	SYM
easat-4310	220	3	3729	3729	NUM
easat-4310	220	4	,	,	PUNCT
easat-4310	220	5	2021	2021	NUM
easat-4310	220	6	.	.	PUNCT
easat-4310	221	1	https://doi.org/10.21608/ejhm.2021.203754	https://doi.org/10.21608/ejhm.2021.203754	PROPN
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easat-4310	222	3	]	]	X
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easat-4310	222	10	al	al	PROPN
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easat-4310	222	13	"	"	PUNCT
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easat-4310	222	15	and	and	CCONJ
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easat-4310	222	17	analysis	analysis	NOUN
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easat-4310	222	19	acute	acute	ADJ
easat-4310	222	20	lymphoblastic	lymphoblastic	ADJ
easat-4310	222	21	leukemia	leukemia	NOUN
easat-4310	222	22	in	in	ADP
easat-4310	222	23	the	the	DET
easat-4310	222	24	pediatric	pediatric	ADJ
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easat-4310	222	32	research	research	NOUN
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easat-4310	222	39	.	.	PUNCT
easat-4310	223	1	13_supplement	13_supplement	NUM
easat-4310	223	2	,	,	PUNCT
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easat-4310	223	4	.	.	PUNCT
easat-4310	224	1	4198	4198	NUM
easat-4310	224	2	-	-	SYM
easat-4310	224	3	4198	4198	NUM
easat-4310	224	4	,	,	PUNCT
easat-4310	224	5	2019	2019	NUM
easat-4310	224	6	.	.	PUNCT
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easat-4310	225	13	2576	2576	NUM
easat-4310	225	14	-	-	SYM
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easat-4310	225	17	.	.	PROPN
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easat-4310	226	4	.	.	NOUN
easat-4310	226	5	1	1	NUM
easat-4310	226	6	:	:	SYM
easat-4310	226	7	1078	1078	NUM
easat-4310	226	8	-	-	SYM
easat-4310	226	9	1085	1085	NUM
easat-4310	226	10	,	,	PUNCT
easat-4310	226	11	2025	2025	NUM
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easat-4310	226	13	:	:	PUNCT
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easat-4310	226	17	by	by	ADP
easat-4310	226	18	the	the	DET
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easat-4310	227	2	8	8	NUM
easat-4310	227	3	]	]	PUNCT
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easat-4310	227	5	zamani	zamani	PROPN
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easat-4310	227	10	,	,	PUNCT
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easat-4310	227	17	,	,	PUNCT
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easat-4310	227	19	mir-324	mir-324	NOUN
easat-4310	227	20	-	-	PUNCT
easat-4310	227	21	3p	3p	NUM
easat-4310	227	22	and	and	CCONJ
easat-4310	227	23	mir-508	mir-508	NOUN
easat-4310	227	24	-	-	PUNCT
easat-4310	227	25	5p	5p	NUM
easat-4310	227	26	expression	expression	NOUN
easat-4310	227	27	levels	level	NOUN
easat-4310	227	28	could	could	AUX
easat-4310	227	29	serve	serve	VERB
easat-4310	227	30	as	as	ADP
easat-4310	227	31	potential	potential	ADJ
easat-4310	227	32	diagnostic	diagnostic	ADJ
easat-4310	227	33	and	and	CCONJ
easat-4310	227	34	multidrug	multidrug	NOUN
easat-4310	227	35	-	-	PUNCT
easat-4310	227	36	resistant	resistant	ADJ
easat-4310	227	37	biomarkers	biomarker	NOUN
easat-4310	227	38	in	in	ADP
easat-4310	227	39	childhood	childhood	NOUN
easat-4310	227	40	acute	acute	NOUN
easat-4310	227	41	lymphoblastic	lymphoblastic	ADJ
easat-4310	227	42	leukemia	leukemia	NOUN
easat-4310	227	43	,	,	PUNCT
easat-4310	227	44	"	"	PUNCT
easat-4310	227	45	leukemia	leukemia	NOUN
easat-4310	227	46	research	research	NOUN
easat-4310	227	47	,	,	PUNCT
easat-4310	227	48	vol	vol	NOUN
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easat-4310	227	51	,	,	PUNCT
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easat-4310	227	54	,	,	PUNCT
easat-4310	227	55	2021	2021	NUM
easat-4310	227	56	.	.	PUNCT
easat-4310	228	1	https://doi.org/10.1016/j.leukres.2021.106643	https://doi.org/10.1016/j.leukres.2021.106643	NOUN
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easat-4310	228	3	9	9	NUM
easat-4310	228	4	]	]	PUNCT
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easat-4310	228	6	s.	s.	PROPN
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easat-4310	228	10	c.	c.	PROPN
easat-4310	228	11	cheung	cheung	PROPN
easat-4310	228	12	,	,	PUNCT
easat-4310	228	13	"	"	PUNCT
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easat-4310	228	15	the	the	DET
easat-4310	228	16	bone	bone	NOUN
easat-4310	228	17	marrow	marrow	NOUN
easat-4310	228	18	microenvironment	microenvironment	NOUN
easat-4310	228	19	:	:	PUNCT
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easat-4310	228	21	novel	novel	ADJ
easat-4310	228	22	therapeutic	therapeutic	ADJ
easat-4310	228	23	strategy	strategy	NOUN
easat-4310	228	24	for	for	ADP
easat-4310	228	25	pre	pre	ADJ
easat-4310	228	26	-	-	ADJ
easat-4310	228	27	b	b	ADJ
easat-4310	228	28	acute	acute	ADJ
easat-4310	228	29	lymphoblastic	lymphoblastic	ADJ
easat-4310	228	30	leukemia	leukemia	NOUN
easat-4310	228	31	,	,	PUNCT
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easat-4310	228	34	,	,	PUNCT
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easat-4310	228	38	,	,	PUNCT
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easat-4310	228	42	,	,	PUNCT
easat-4310	228	43	p.	p.	NOUN
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easat-4310	228	45	,	,	PUNCT
easat-4310	228	46	2019	2019	NUM
easat-4310	228	47	.	.	PUNCT
easat-4310	229	1	https://doi.org/10.18632/oncotarget.26720	https://doi.org/10.18632/oncotarget.26720	PROPN
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easat-4310	229	3	10	10	NUM
easat-4310	229	4	]	]	X
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easat-4310	229	13	,	,	PUNCT
easat-4310	229	14	and	and	CCONJ
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easat-4310	229	41	.	.	PROPN
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easat-4310	229	46	5	5	NUM
easat-4310	229	47	,	,	PUNCT
easat-4310	229	48	p.	p.	NOUN
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easat-4310	229	50	,	,	PUNCT
easat-4310	229	51	2022	2022	NUM
easat-4310	229	52	.	.	PUNCT
easat-4310	230	1	https://doi.org/10.3390/ijms23052755	https://doi.org/10.3390/ijms23052755	ADJ
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easat-4310	230	3	11	11	NUM
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easat-4310	230	10	,	,	PUNCT
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easat-4310	230	25	early	early	ADJ
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easat-4310	230	28	hematopoietic	hematopoietic	ADJ
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easat-4310	230	30	transplantation	transplantation	NOUN
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easat-4310	231	2	,	,	PUNCT
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easat-4310	231	4	.	.	NOUN
easat-4310	231	5	1	1	NUM
easat-4310	231	6	,	,	PUNCT
easat-4310	231	7	p.	p.	NOUN
easat-4310	231	8	1	1	NUM
easat-4310	231	9	,	,	PUNCT
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easat-4310	231	11	.	.	PUNCT
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easat-4310	233	2	12	12	NUM
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easat-4310	233	27	:	:	PUNCT
easat-4310	233	28	the	the	DET
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easat-4310	233	41	-	-	PUNCT
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easat-4310	233	43	-	-	PUNCT
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easat-4310	233	45	-	-	PUNCT
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easat-4310	233	47	-	-	PUNCT
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easat-4310	233	51	"	"	PUNCT
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easat-4310	233	53	opinion	opinion	NOUN
easat-4310	233	54	in	in	ADP
easat-4310	233	55	clinical	clinical	ADJ
easat-4310	233	56	nutrition	nutrition	NOUN
easat-4310	233	57	&	&	CCONJ
easat-4310	233	58	metabolic	metabolic	PROPN
easat-4310	233	59	care	care	PROPN
easat-4310	233	60	,	,	PUNCT
easat-4310	233	61	vol	vol	NOUN
easat-4310	233	62	.	.	PROPN
easat-4310	233	63	24	24	NUM
easat-4310	233	64	,	,	PUNCT
easat-4310	233	65	no	no	INTJ
easat-4310	233	66	.	.	NOUN
easat-4310	233	67	5	5	NUM
easat-4310	233	68	,	,	PUNCT
easat-4310	233	69	pp	pp	ADJ
easat-4310	233	70	.	.	PUNCT
easat-4310	234	1	416	416	NUM
easat-4310	234	2	-	-	SYM
easat-4310	234	3	427	427	NUM
easat-4310	234	4	,	,	PUNCT
easat-4310	234	5	2021	2021	NUM
easat-4310	234	6	.	.	PUNCT
easat-4310	235	1	https://doi.org/10.1097/mco.0000000000000773	https://doi.org/10.1097/mco.0000000000000773	PROPN
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easat-4310	236	2	13	13	NUM
easat-4310	236	3	]	]	PUNCT
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easat-4310	237	1	c.	c.	PROPN
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easat-4310	237	4	a.	a.	NOUN
easat-4310	237	5	forbes	forbes	PROPN
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easat-4310	237	7	"	"	PUNCT
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easat-4310	237	10	a	a	DET
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easat-4310	237	14	function	function	NOUN
easat-4310	237	15	and	and	CCONJ
easat-4310	237	16	absorption	absorption	NOUN
easat-4310	237	17	in	in	ADP
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easat-4310	237	19	settings	setting	NOUN
easat-4310	237	20	:	:	PUNCT
easat-4310	237	21	a	a	DET
easat-4310	237	22	systematic	systematic	ADJ
easat-4310	237	23	review	review	NOUN
easat-4310	237	24	and	and	CCONJ
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easat-4310	237	26	-	-	PUNCT
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easat-4310	237	29	"	"	PUNCT
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easat-4310	237	31	european	european	PROPN
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easat-4310	237	33	journal	journal	PROPN
easat-4310	237	34	,	,	PUNCT
easat-4310	237	35	vol	vol	NOUN
easat-4310	237	36	.	.	PROPN
easat-4310	237	37	6	6	NUM
easat-4310	237	38	,	,	PUNCT
easat-4310	237	39	no	no	INTJ
easat-4310	237	40	.	.	NOUN
easat-4310	237	41	2	2	NUM
easat-4310	237	42	,	,	PUNCT
easat-4310	237	43	pp	pp	ADJ
easat-4310	237	44	.	.	PUNCT
easat-4310	238	1	181	181	NUM
easat-4310	238	2	-	-	SYM
easat-4310	238	3	191	191	NUM
easat-4310	238	4	,	,	PUNCT
easat-4310	238	5	2018	2018	NUM
easat-4310	238	6	.	.	PUNCT
easat-4310	239	1	https://doi.org/10.1177/2050640617737632	https://doi.org/10.1177/2050640617737632	NOUN
easat-4310	240	1	[	[	X
easat-4310	240	2	14	14	NUM
easat-4310	240	3	]	]	PUNCT
easat-4310	240	4	a.	a.	NOUN
easat-4310	240	5	lomash	lomash	NOUN
easat-4310	240	6	et	et	PROPN
easat-4310	241	1	al	al	PROPN
easat-4310	241	2	.	.	PROPN
easat-4310	241	3	,	,	PUNCT
easat-4310	241	4	"	"	PUNCT
easat-4310	241	5	evaluation	evaluation	NOUN
easat-4310	241	6	of	of	ADP
easat-4310	241	7	the	the	DET
easat-4310	241	8	utility	utility	NOUN
easat-4310	241	9	of	of	ADP
easat-4310	241	10	amino	amino	NOUN
easat-4310	241	11	acid	acid	NOUN
easat-4310	241	12	citrulline	citrulline	NOUN
easat-4310	241	13	as	as	ADP
easat-4310	241	14	a	a	DET
easat-4310	241	15	surrogate	surrogate	ADJ
easat-4310	241	16	metabolomic	metabolomic	ADJ
easat-4310	241	17	biomarker	biomarker	NOUN
easat-4310	241	18	for	for	ADP
easat-4310	241	19	the	the	DET
easat-4310	241	20	diagnosis	diagnosis	NOUN
easat-4310	241	21	of	of	ADP
easat-4310	241	22	celiac	celiac	ADJ
easat-4310	241	23	disease	disease	NOUN
easat-4310	241	24	,	,	PUNCT
easat-4310	241	25	"	"	PUNCT
easat-4310	241	26	nutrition	nutrition	NOUN
easat-4310	241	27	and	and	CCONJ
easat-4310	241	28	metabolic	metabolic	NOUN
easat-4310	241	29	insights	insight	NOUN
easat-4310	241	30	,	,	PUNCT
easat-4310	241	31	vol	vol	NOUN
easat-4310	241	32	.	.	PROPN
easat-4310	241	33	14	14	NUM
easat-4310	241	34	,	,	PUNCT
easat-4310	241	35	p.	p.	NOUN
easat-4310	241	36	11786388211060603	11786388211060603	NUM
easat-4310	241	37	,	,	PUNCT
easat-4310	241	38	2021	2021	NUM
easat-4310	241	39	.	.	PUNCT
easat-4310	242	1	https://doi.org/10.1177/11786388211060603	https://doi.org/10.1177/11786388211060603	NOUN
easat-4310	243	1	[	[	X
easat-4310	243	2	15	15	NUM
easat-4310	243	3	]	]	PUNCT
easat-4310	243	4	j.	j.	PROPN
easat-4310	243	5	teng	teng	PROPN
easat-4310	243	6	,	,	PUNCT
easat-4310	243	7	l.	l.	PROPN
easat-4310	243	8	xiang	xiang	PROPN
easat-4310	243	9	,	,	PUNCT
easat-4310	243	10	h.	h.	PROPN
easat-4310	243	11	long	long	PROPN
easat-4310	243	12	,	,	PUNCT
easat-4310	243	13	c.	c.	PROPN
easat-4310	243	14	gao	gao	PROPN
easat-4310	243	15	,	,	PUNCT
easat-4310	243	16	l.	l.	PROPN
easat-4310	243	17	lei	lei	PROPN
easat-4310	243	18	,	,	PUNCT
easat-4310	243	19	and	and	CCONJ
easat-4310	243	20	y.	y.	PROPN
easat-4310	243	21	zhang	zhang	PROPN
easat-4310	243	22	,	,	PUNCT
easat-4310	243	23	"	"	PUNCT
easat-4310	243	24	the	the	DET
easat-4310	243	25	serum	serum	NOUN
easat-4310	243	26	citrulline	citrulline	NOUN
easat-4310	243	27	and	and	CCONJ
easat-4310	243	28	d	d	NOUN
easat-4310	243	29	-	-	PUNCT
easat-4310	243	30	lactate	lactate	NOUN
easat-4310	243	31	are	be	AUX
easat-4310	243	32	associated	associate	VERB
easat-4310	243	33	with	with	ADP
easat-4310	243	34	gastrointestinal	gastrointestinal	ADJ
easat-4310	243	35	dysfunction	dysfunction	NOUN
easat-4310	243	36	and	and	CCONJ
easat-4310	243	37	failure	failure	NOUN
easat-4310	243	38	in	in	ADP
easat-4310	243	39	critically	critically	ADV
easat-4310	243	40	ill	ill	ADJ
easat-4310	243	41	patients	patient	NOUN
easat-4310	243	42	,	,	PUNCT
easat-4310	243	43	"	"	PUNCT
easat-4310	243	44	international	international	ADJ
easat-4310	243	45	journal	journal	NOUN
easat-4310	243	46	of	of	ADP
easat-4310	243	47	general	general	ADJ
easat-4310	243	48	medicine	medicine	NOUN
easat-4310	243	49	,	,	PUNCT
easat-4310	243	50	pp	pp	ADP
easat-4310	243	51	.	.	PUNCT
easat-4310	243	52	41254134	41254134	NUM
easat-4310	243	53	,	,	PUNCT
easat-4310	243	54	2021	2021	NUM
easat-4310	243	55	.	.	PUNCT
easat-4310	244	1	https://doi.org/10.2147/ijgm.s305209	https://doi.org/10.2147/ijgm.s305209	VERB
easat-4310	245	1	[	[	X
easat-4310	245	2	16	16	NUM
easat-4310	245	3	]	]	PUNCT
easat-4310	245	4	s.	s.	PROPN
easat-4310	245	5	weischendorff	weischendorff	PROPN
easat-4310	245	6	et	et	PROPN
easat-4310	245	7	al	al	PROPN
easat-4310	245	8	.	.	PROPN
easat-4310	245	9	,	,	PUNCT
easat-4310	245	10	"	"	PUNCT
easat-4310	245	11	intestinal	intestinal	ADJ
easat-4310	245	12	mucositis	mucositis	NOUN
easat-4310	245	13	,	,	PUNCT
easat-4310	245	14	systemic	systemic	ADJ
easat-4310	245	15	inflammation	inflammation	NOUN
easat-4310	245	16	and	and	CCONJ
easat-4310	245	17	bloodstream	bloodstream	NOUN
easat-4310	245	18	infections	infection	NOUN
easat-4310	245	19	following	follow	VERB
easat-4310	245	20	high‐dose	high‐dose	PRON
easat-4310	245	21	methotrexate	methotrexate	NOUN
easat-4310	245	22	treatment	treatment	NOUN
easat-4310	245	23	in	in	ADP
easat-4310	245	24	childhood	childhood	NOUN
easat-4310	245	25	acute	acute	NOUN
easat-4310	245	26	lymphoblastic	lymphoblastic	ADJ
easat-4310	245	27	leukaemia	leukaemia	NOUN
easat-4310	245	28	:	:	PUNCT
easat-4310	245	29	comparison	comparison	NOUN
easat-4310	245	30	between	between	ADP
easat-4310	245	31	the	the	DET
easat-4310	245	32	nopho	nopho	NOUN
easat-4310	245	33	all	all	DET
easat-4310	245	34	2008	2008	NUM
easat-4310	245	35	protocol	protocol	NOUN
easat-4310	245	36	and	and	CCONJ
easat-4310	245	37	the	the	DET
easat-4310	245	38	alltogether1	alltogether1	PROPN
easat-4310	245	39	protocol	protocol	NOUN
easat-4310	245	40	,	,	PUNCT
easat-4310	245	41	"	"	PUNCT
easat-4310	245	42	international	international	ADJ
easat-4310	245	43	journal	journal	NOUN
easat-4310	245	44	of	of	ADP
easat-4310	245	45	cancer	cancer	NOUN
easat-4310	245	46	,	,	PUNCT
easat-4310	245	47	vol	vol	NOUN
easat-4310	245	48	.	.	PROPN
easat-4310	246	1	156	156	NUM
easat-4310	246	2	,	,	PUNCT
easat-4310	246	3	no	no	INTJ
easat-4310	246	4	.	.	NOUN
easat-4310	246	5	1	1	NUM
easat-4310	246	6	,	,	PUNCT
easat-4310	246	7	pp	pp	ADJ
easat-4310	246	8	.	.	PUNCT
easat-4310	247	1	164	164	NUM
easat-4310	247	2	-	-	SYM
easat-4310	247	3	173	173	NUM
easat-4310	247	4	,	,	PUNCT
easat-4310	247	5	2025	2025	NUM
easat-4310	247	6	.	.	PUNCT
easat-4310	248	1	https://doi.org/10.1002/ijc.35136	https://doi.org/10.1002/ijc.35136	NOUN
easat-4310	249	1	[	[	X
easat-4310	249	2	17	17	NUM
easat-4310	249	3	]	]	PUNCT
easat-4310	249	4	s.	s.	PROPN
easat-4310	249	5	de	de	PROPN
easat-4310	249	6	pietri	pietri	PROPN
easat-4310	249	7	et	et	PROPN
easat-4310	249	8	al	al	PROPN
easat-4310	249	9	.	.	PROPN
easat-4310	249	10	,	,	PUNCT
easat-4310	249	11	"	"	PUNCT
easat-4310	249	12	gastrointestinal	gastrointestinal	ADJ
easat-4310	249	13	barrier	barrier	NOUN
easat-4310	249	14	integrity	integrity	NOUN
easat-4310	249	15	and	and	CCONJ
easat-4310	249	16	mucosal	mucosal	ADJ
easat-4310	249	17	inflammation	inflammation	NOUN
easat-4310	249	18	as	as	ADP
easat-4310	249	19	risk	risk	NOUN
easat-4310	249	20	factors	factor	NOUN
easat-4310	249	21	of	of	ADP
easat-4310	249	22	blood	blood	NOUN
easat-4310	249	23	stream	stream	NOUN
easat-4310	249	24	infections	infection	NOUN
easat-4310	249	25	in	in	ADP
easat-4310	249	26	children	child	NOUN
easat-4310	249	27	treated	treat	VERB
easat-4310	249	28	for	for	ADP
easat-4310	249	29	acute	acute	ADJ
easat-4310	249	30	lymphoblastic	lymphoblastic	ADJ
easat-4310	249	31	leukaemia	leukaemia	NOUN
easat-4310	249	32	,	,	PUNCT
easat-4310	249	33	"	"	PUNCT
easat-4310	249	34	international	international	ADJ
easat-4310	249	35	journal	journal	NOUN
easat-4310	249	36	of	of	ADP
easat-4310	249	37	cancer	cancer	NOUN
easat-4310	249	38	,	,	PUNCT
easat-4310	249	39	vol	vol	NOUN
easat-4310	249	40	.	.	PROPN
easat-4310	249	41	153	153	NUM
easat-4310	249	42	,	,	PUNCT
easat-4310	249	43	no	no	INTJ
easat-4310	249	44	.	.	NOUN
easat-4310	249	45	9	9	NUM
easat-4310	249	46	,	,	PUNCT
easat-4310	249	47	pp	pp	ADJ
easat-4310	249	48	.	.	PUNCT
easat-4310	250	1	1635	1635	NUM
easat-4310	250	2	-	-	SYM
easat-4310	250	3	1642	1642	NUM
easat-4310	250	4	,	,	PUNCT
easat-4310	250	5	2023	2023	NUM
easat-4310	250	6	.	.	PUNCT
easat-4310	251	1	https://doi.org/10.1002/ijc.34639	https://doi.org/10.1002/ijc.34639	PROPN
easat-4310	251	2	[	[	X
easat-4310	251	3	18	18	NUM
easat-4310	251	4	]	]	PUNCT
easat-4310	251	5	m.	m.	NOUN
easat-4310	251	6	tyszko	tyszko	PROPN
easat-4310	251	7	et	et	PROPN
easat-4310	251	8	al	al	PROPN
easat-4310	251	9	.	.	PROPN
easat-4310	251	10	,	,	PUNCT
easat-4310	251	11	"	"	PUNCT
easat-4310	251	12	citrulline	citrulline	NOUN
easat-4310	251	13	,	,	PUNCT
easat-4310	251	14	intestinal	intestinal	ADJ
easat-4310	251	15	fatty	fatty	NOUN
easat-4310	251	16	acid	acid	NOUN
easat-4310	251	17	-	-	PUNCT
easat-4310	251	18	binding	bind	VERB
easat-4310	251	19	protein	protein	NOUN
easat-4310	251	20	and	and	CCONJ
easat-4310	251	21	the	the	DET
easat-4310	251	22	acute	acute	ADJ
easat-4310	251	23	gastrointestinal	gastrointestinal	ADJ
easat-4310	251	24	injury	injury	NOUN
easat-4310	251	25	score	score	NOUN
easat-4310	251	26	as	as	ADP
easat-4310	251	27	predictors	predictor	NOUN
easat-4310	251	28	of	of	ADP
easat-4310	251	29	gastrointestinal	gastrointestinal	ADJ
easat-4310	251	30	failure	failure	NOUN
easat-4310	251	31	in	in	ADP
easat-4310	251	32	patients	patient	NOUN
easat-4310	251	33	with	with	ADP
easat-4310	251	34	sepsis	sepsis	NOUN
easat-4310	251	35	and	and	CCONJ
easat-4310	251	36	septic	septic	ADJ
easat-4310	251	37	shock	shock	NOUN
easat-4310	251	38	,	,	PUNCT
easat-4310	251	39	"	"	PUNCT
easat-4310	251	40	nutrients	nutrient	NOUN
easat-4310	251	41	,	,	PUNCT
easat-4310	251	42	vol	vol	NOUN
easat-4310	251	43	.	.	PROPN
easat-4310	251	44	15	15	NUM
easat-4310	251	45	,	,	PUNCT
easat-4310	251	46	no	no	INTJ
easat-4310	251	47	.	.	NOUN
easat-4310	251	48	9	9	NUM
easat-4310	251	49	,	,	PUNCT
easat-4310	251	50	p.	p.	NOUN
easat-4310	251	51	2100	2100	NUM
easat-4310	251	52	,	,	PUNCT
easat-4310	251	53	2023	2023	NUM
easat-4310	251	54	.	.	PUNCT
easat-4310	252	1	https://doi.org/10.3390/nu15092100	https://doi.org/10.3390/nu15092100	PROPN
easat-4310	253	1	[	[	X
easat-4310	253	2	19	19	NUM
easat-4310	253	3	]	]	PUNCT
easat-4310	253	4	s.	s.	PROPN
easat-4310	253	5	jäckel	jäckel	PROPN
easat-4310	253	6	et	et	PROPN
easat-4310	253	7	al	al	PROPN
easat-4310	253	8	.	.	PROPN
easat-4310	253	9	,	,	PUNCT
easat-4310	253	10	"	"	PUNCT
easat-4310	253	11	l	l	NOUN
easat-4310	253	12	-	-	NOUN
easat-4310	253	13	citrulline	citrulline	NOUN
easat-4310	253	14	:	:	PUNCT
easat-4310	253	15	a	a	DET
easat-4310	253	16	preclinical	preclinical	ADJ
easat-4310	253	17	safety	safety	NOUN
easat-4310	253	18	biomarker	biomarker	NOUN
easat-4310	253	19	for	for	ADP
easat-4310	253	20	the	the	DET
easat-4310	253	21	small	small	ADJ
easat-4310	253	22	intestine	intestine	NOUN
easat-4310	253	23	in	in	ADP
easat-4310	253	24	rats	rat	NOUN
easat-4310	253	25	and	and	CCONJ
easat-4310	253	26	dogs	dog	NOUN
easat-4310	253	27	in	in	ADP
easat-4310	253	28	repeat	repeat	NOUN
easat-4310	253	29	dose	dose	NOUN
easat-4310	253	30	toxicity	toxicity	NOUN
easat-4310	253	31	studies	study	NOUN
easat-4310	253	32	,	,	PUNCT
easat-4310	253	33	"	"	PUNCT
easat-4310	253	34	journal	journal	NOUN
easat-4310	253	35	of	of	ADP
easat-4310	253	36	pharmacological	pharmacological	ADJ
easat-4310	253	37	and	and	CCONJ
easat-4310	253	38	toxicological	toxicological	ADJ
easat-4310	253	39	methods	method	NOUN
easat-4310	253	40	,	,	PUNCT
easat-4310	253	41	vol	vol	NOUN
easat-4310	253	42	.	.	NOUN
easat-4310	253	43	111	111	NUM
easat-4310	253	44	,	,	PUNCT
easat-4310	253	45	p.	p.	NOUN
easat-4310	253	46	107110	107110	NUM
easat-4310	253	47	,	,	PUNCT
easat-4310	253	48	2021	2021	NUM
easat-4310	253	49	.	.	PUNCT
easat-4310	254	1	https://doi.org/10.1016/j.vascn.2021.107110	https://doi.org/10.1016/j.vascn.2021.107110	ADJ
easat-4310	254	2	[	[	X
easat-4310	254	3	20	20	NUM
easat-4310	254	4	]	]	PUNCT
easat-4310	254	5	a.	a.	NOUN
easat-4310	254	6	khavkin	khavkin	PROPN
easat-4310	254	7	,	,	PUNCT
easat-4310	254	8	v.	v.	CCONJ
easat-4310	254	9	novikova	novikova	NUM
easat-4310	254	10	,	,	PUNCT
easat-4310	254	11	and	and	CCONJ
easat-4310	254	12	n.	n.	PROPN
easat-4310	254	13	shapovalova	shapovalova	PROPN
easat-4310	254	14	,	,	PUNCT
easat-4310	254	15	"	"	PUNCT
easat-4310	254	16	perspective	perspective	ADJ
easat-4310	254	17	non	non	ADJ
easat-4310	254	18	-	-	ADJ
easat-4310	254	19	invasive	invasive	ADJ
easat-4310	254	20	biomarkers	biomarker	NOUN
easat-4310	254	21	:	:	PUNCT
easat-4310	254	22	intestinal	intestinal	ADJ
easat-4310	254	23	proteins	protein	NOUN
easat-4310	254	24	in	in	ADP
easat-4310	254	25	the	the	DET
easat-4310	254	26	diagnosis	diagnosis	NOUN
easat-4310	254	27	for	for	ADP
easat-4310	254	28	diagnosis	diagnosis	NOUN
easat-4310	254	29	and	and	CCONJ
easat-4310	254	30	control	control	NOUN
easat-4310	254	31	of	of	ADP
easat-4310	254	32	intestinal	intestinal	ADJ
easat-4310	254	33	mucosal	mucosal	NOUN
easat-4310	254	34	damage	damage	NOUN
easat-4310	254	35	,	,	PUNCT
easat-4310	254	36	"	"	PUNCT
easat-4310	254	37	experimental	experimental	ADJ
easat-4310	254	38	and	and	CCONJ
easat-4310	254	39	clinical	clinical	ADJ
easat-4310	254	40	gastroenterology	gastroenterology	NOUN
easat-4310	254	41	,	,	PUNCT
easat-4310	254	42	vol	vol	NOUN
easat-4310	254	43	.	.	PROPN
easat-4310	254	44	4	4	NUM
easat-4310	254	45	,	,	PUNCT
easat-4310	254	46	pp	pp	ADJ
easat-4310	254	47	.	.	PUNCT
easat-4310	255	1	155	155	NUM
easat-4310	255	2	-	-	SYM
easat-4310	255	3	160	160	NUM
easat-4310	255	4	,	,	PUNCT
easat-4310	255	5	2021	2021	NUM
easat-4310	255	6	.	.	PUNCT
easat-4310	256	1	https://doi.org/10.31146/1682-8658-ecg-188-4-155-160	https://doi.org/10.31146/1682-8658-ecg-188-4-155-160	PROPN
easat-4310	257	1	[	[	X
easat-4310	257	2	21	21	NUM
easat-4310	257	3	]	]	X
easat-4310	257	4	h.	h.	PROPN
easat-4310	257	5	maslova	maslova	PROPN
easat-4310	257	6	and	and	CCONJ
easat-4310	257	7	i.	i.	PROPN
easat-4310	257	8	skrypnyk	skrypnyk	PROPN
easat-4310	257	9	,	,	PUNCT
easat-4310	257	10	"	"	PUNCT
easat-4310	257	11	chemotherapy	chemotherapy	NOUN
easat-4310	257	12	effect	effect	NOUN
easat-4310	257	13	on	on	ADP
easat-4310	257	14	arginine	arginine	NOUN
easat-4310	257	15	/	/	SYM
easat-4310	257	16	citrulline	citrulline	NOUN
easat-4310	257	17	cycle	cycle	NOUN
easat-4310	257	18	indicators	indicator	NOUN
easat-4310	257	19	in	in	ADP
easat-4310	257	20	patients	patient	NOUN
easat-4310	257	21	with	with	ADP
easat-4310	257	22	acute	acute	ADJ
easat-4310	257	23	myeloid	myeloid	NOUN
easat-4310	257	24	leukemia	leukemia	NOUN
easat-4310	257	25	and	and	CCONJ
easat-4310	257	26	concomitant	concomitant	ADJ
easat-4310	257	27	obesity	obesity	NOUN
easat-4310	257	28	,	,	PUNCT
easat-4310	257	29	"	"	PUNCT
easat-4310	257	30	medicni	medicni	ADJ
easat-4310	257	31	perspektivi	perspektivi	NOUN
easat-4310	257	32	,	,	PUNCT
easat-4310	257	33	vol	vol	NOUN
easat-4310	257	34	.	.	PROPN
easat-4310	258	1	25	25	NUM
easat-4310	258	2	,	,	PUNCT
easat-4310	258	3	no	no	INTJ
easat-4310	258	4	.	.	NOUN
easat-4310	258	5	2	2	NUM
easat-4310	258	6	,	,	PUNCT
easat-4310	258	7	pp	pp	ADJ
easat-4310	258	8	.	.	PUNCT
easat-4310	259	1	103	103	NUM
easat-4310	259	2	-	-	SYM
easat-4310	259	3	108	108	NUM
easat-4310	259	4	,	,	PUNCT
easat-4310	259	5	2020	2020	NUM
easat-4310	259	6	.	.	PUNCT
easat-4310	260	1	https://doi.org/10.26641/2307-0404.2020.2.206378	https://doi.org/10.26641/2307-0404.2020.2.206378	PROPN
easat-4310	261	1	[	[	X
easat-4310	261	2	22	22	NUM
easat-4310	261	3	]	]	PUNCT
easat-4310	261	4	k.	k.	PROPN
easat-4310	262	1	v.	v.	PROPN
easat-4310	262	2	koelfat	koelfat	PROPN
easat-4310	262	3	et	et	PROPN
easat-4310	262	4	al	al	PROPN
easat-4310	262	5	.	.	PROPN
easat-4310	262	6	,	,	PUNCT
easat-4310	262	7	"	"	PUNCT
easat-4310	262	8	low	low	ADJ
easat-4310	262	9	circulating	circulate	VERB
easat-4310	262	10	concentrations	concentration	NOUN
easat-4310	262	11	of	of	ADP
easat-4310	262	12	citrulline	citrulline	NOUN
easat-4310	262	13	and	and	CCONJ
easat-4310	262	14	fgf19	fgf19	NOUN
easat-4310	262	15	predict	predict	VERB
easat-4310	262	16	chronic	chronic	ADJ
easat-4310	262	17	cholestasis	cholestasis	NOUN
easat-4310	262	18	and	and	CCONJ
easat-4310	262	19	poor	poor	ADJ
easat-4310	262	20	survival	survival	NOUN
easat-4310	262	21	in	in	ADP
easat-4310	262	22	adult	adult	NOUN
easat-4310	262	23	patients	patient	NOUN
easat-4310	262	24	with	with	ADP
easat-4310	262	25	chronic	chronic	ADJ
easat-4310	262	26	intestinal	intestinal	ADJ
easat-4310	262	27	failure	failure	NOUN
easat-4310	262	28	:	:	PUNCT
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easat-4310	262	30	of	of	ADP
easat-4310	262	31	a	a	DET
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easat-4310	262	38	failure	failure	NOUN
easat-4310	262	39	(	(	PUNCT
easat-4310	262	40	mesif	mesif	NOUN
easat-4310	262	41	risk	risk	NOUN
easat-4310	262	42	score	score	NOUN
easat-4310	262	43	)	)	PUNCT
easat-4310	262	44	,	,	PUNCT
easat-4310	262	45	"	"	PUNCT
easat-4310	262	46	the	the	DET
easat-4310	262	47	american	american	PROPN
easat-4310	262	48	journal	journal	PROPN
easat-4310	262	49	of	of	ADP
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easat-4310	262	51	nutrition	nutrition	NOUN
easat-4310	262	52	,	,	PUNCT
easat-4310	262	53	vol	vol	NOUN
easat-4310	262	54	.	.	PROPN
easat-4310	262	55	109	109	NUM
easat-4310	262	56	,	,	PUNCT
easat-4310	262	57	no	no	INTJ
easat-4310	262	58	.	.	NOUN
easat-4310	262	59	6	6	NUM
easat-4310	262	60	,	,	PUNCT
easat-4310	262	61	pp	pp	ADJ
easat-4310	262	62	.	.	PUNCT
easat-4310	262	63	1620	1620	NUM
easat-4310	262	64	-	-	SYM
easat-4310	262	65	1629	1629	NUM
easat-4310	262	66	,	,	PUNCT
easat-4310	262	67	2019	2019	NUM
easat-4310	262	68	.	.	PUNCT
easat-4310	263	1	https://doi.org/10.1093/ajcn/nqz036	https://doi.org/10.1093/ajcn/nqz036	NOUN
easat-4310	264	1	[	[	X
easat-4310	264	2	23	23	NUM
easat-4310	264	3	]	]	X
easat-4310	264	4	d.	d.	PROPN
easat-4310	264	5	s.	s.	PROPN
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easat-4310	264	7	et	et	PROPN
easat-4310	264	8	al	al	PROPN
easat-4310	264	9	.	.	PROPN
easat-4310	264	10	,	,	PUNCT
easat-4310	264	11	"	"	PUNCT
easat-4310	264	12	tpmt	tpmt	NOUN
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easat-4310	264	14	variability	variability	NOUN
easat-4310	264	15	and	and	CCONJ
easat-4310	264	16	its	its	PRON
easat-4310	264	17	association	association	NOUN
easat-4310	264	18	with	with	ADP
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easat-4310	264	20	in	in	ADP
easat-4310	264	21	indonesian	indonesian	ADJ
easat-4310	264	22	children	child	NOUN
easat-4310	264	23	with	with	ADP
easat-4310	264	24	acute	acute	ADJ
easat-4310	264	25	lymphoblastic	lymphoblastic	ADJ
easat-4310	264	26	leukemia	leukemia	NOUN
easat-4310	264	27	in	in	ADP
easat-4310	264	28	maintenance	maintenance	NOUN
easat-4310	264	29	therapy	therapy	NOUN
easat-4310	264	30	,	,	PUNCT
easat-4310	264	31	"	"	PUNCT
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easat-4310	264	33	and	and	CCONJ
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easat-4310	264	37	pp	pp	ADP
easat-4310	264	38	.	.	PUNCT
easat-4310	265	1	199	199	NUM
easat-4310	265	2	-	-	SYM
easat-4310	265	3	210	210	NUM
easat-4310	265	4	,	,	PUNCT
easat-4310	265	5	2021	2021	NUM
easat-4310	265	6	.	.	PUNCT
easat-4310	266	1	https://doi.org/10.2147/pgpm.s288988	https://doi.org/10.2147/pgpm.s288988	VERB
easat-4310	267	1	[	[	X
easat-4310	267	2	24	24	NUM
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easat-4310	267	21	and	and	CCONJ
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easat-4310	267	39	leukaemia	leukaemia	NOUN
easat-4310	267	40	,	,	PUNCT
easat-4310	267	41	"	"	PUNCT
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easat-4310	268	6	,	,	PUNCT
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easat-4310	268	9	,	,	PUNCT
easat-4310	268	10	2021	2021	NUM
easat-4310	268	11	.	.	PUNCT
easat-4310	269	1	https://doi.org/10.1002/pbc.28793	https://doi.org/10.1002/pbc.28793	PROPN
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easat-4310	269	11	testing	testing	NOUN
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easat-4310	269	14	care	care	NOUN
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easat-4310	269	16	children	child	NOUN
easat-4310	269	17	with	with	ADP
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easat-4310	269	19	hematologic	hematologic	NOUN
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easat-4310	269	23	blood	blood	NOUN
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easat-4310	271	41	,	,	PUNCT
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easat-4310	271	43	.	.	PUNCT
easat-4310	272	1	https://doi.org/10.3389/fphar.2023.1278769	https://doi.org/10.3389/fphar.2023.1278769	PROPN
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easat-4310	274	27	.	.	PUNCT
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