Electronic Journal of Differential Equations, Vol. 2025 (2025), No. 44, pp. 1–15. ISSN: 1072-6691. URL: https://ejde.math.txstate.edu, https://ejde.math.unt.edu DOI: 10.58997/ejde.2025.44 EXISTENCE OF POSITIVE S-ASYMPTOTICALLY ω-PERIODIC SOLUTIONS OF TIME-SPACE FRACTIONAL NONLOCAL REACTION-DIFFUSION EQUATIONS XUPING ZHANG, KAIBO DING, PENGYU CHEN Abstract. This article studies the asymptotically periodic problem of time-space fractional reaction-diffusion equations with nonlocal initial conditions on infinite intervals. Without the assumption of upper and lower S-asymptotically ω-periodic solutions, the existence results of positive S-asymptotically ω-periodic solutions for a class of abstract time-space fractional evolu- tion equations with nonlocal initial conditions under growth and order conditions are obtained by using the theory of operator semigroups and the method of monotone iteration. Finally, the abstract results were applied to time-space fractional reaction-diffusion equations with nonlocal initial conditions and some new results were obtained. 1. Introduction In this article, we study the positive S-asymptotically ω-periodic solutions for the following time-space fractional reaction-diffusion equation with nonlocal initial conditions cDα t u(t, x) + (−∆)βu(t, x) = F (t, u(t, x)), (t, x) ∈ [0,+∞)× Ω, u(t, x) = 0, (t, x) ∈ [0,+∞)× ∂Ω, u(0, x) = u0(x) + m∑ k=1 aku(Tk, x), x ∈ Ω, (1.1) where cDα t is the Caputo fractional derivative of order 0 < α < 1, (−∆)β is a fractional Laplacian with 0 < β < 1 , Ω is a bounded open domain in Rn, 0 < T1 < T2 < · · · < Tm < +∞, ak ̸= 0 are real numbers, k = 1, 2, . . . ,m, F : [0,+∞)× R → R is a continuous function. It is well known that many realistic models are not strictly periodic. Therefore, since the concept of S-asymptotically ω-periodic function was introduced in [20], asymptotically periodic problems have been rapidly developed due to their broad physical background and realistic mathematical models. In particular, the hereditary and memorability of fractional derivatives provides an ideal tool for describing many phenomena and processes. It is worth noting that there are many relevant results on the existence and uniqueness of S-asymptotically ω-periodic solutions to fractional differential equations, one can refer to [3, 5, 6, 7, 22, 26] and references therein. In addition, in many specific system applications, sometimes only positive solutions are sig- nificant. In recent years, there are many results on the existence of positive solutions for frac- tional differential equations, one can see [14, 17, 21, 25, 33]. However, the existence of positive S-asymptotically ω-periodic solutions on infinite intervals are few. Shu [29] investigated the exis- tence of the positive S-asymptotically ω-periodic solutions to a class of semilinear neutral Caputo fractional differential equations with infinite delay. Li et al. [23] discussed the asymptotically periodic problem for the abstract fractional evolution equation under order conditions and growth conditions as well as obtained some new results on the existence of the positive S-asymptotically 2020 Mathematics Subject Classification. 35R11, 35B09, 34G20, 47J35. Key words and phrases. Time-space fractional reaction-diffusion equation; nonlocal initial conditions; positive S-asymptotically ω-periodic mild solutions; monotone iterative technique. ©2025. This work is licensed under a CC BY 4.0 license. Submitted July 13, 2024. Published April 24, 2025. 1 2 X. ZHANG, K. DING, P. CHEN EJDE-2025/44 ω-periodic mild solutions. Gou [18] investigated the existence of minimal positive S-asymptotically ω-periodic mild solution for structural damped elastic systems with delay and nonlocal conditions on infinite interval. Besides, Gou [19] studied the existence of minimal positive S-asymptotically ω-periodic mild solution for abstract evolution equation with delay on infinite interval. Further- more, compared to the classical conditions, the nonlocal initial conditions are more practical when describe some physical phenomena. It is worth noting that there are many relevant results on nonlocal problems. For more details of nonlocal conditions, one can see [9, 10, 11, 12, 34] and references therein. Inspired by the above work, we are concerned about the positive S-asymptotically ω-periodic solutions of nonlocal problem (1.1). The organization of this paper can be described as follows. In the Section 2, we collect some necessary definitions and preliminary facts. In Section 3, we present our abstract results. In the last section, applying our abstract results to nonlocal problem (1.1), we prove the existence of positive S-asymptotically ω-periodic solutions. 2. Preliminaries Unless stated otherwise, we will assume that (E, ∥ · ∥) is an ordered Banach space with partial order “≤”, whose positive cone P = {u ∈ E : u ≥ θ} is normal with normal constant N , θ is the zero element of E. Combining property of exponential functions, define a Banach space Ce([0,∞), E) = {u ∈ C([0,∞), E) : lim t→∞ e−t∥u(t)∥ = 0} with the norm ∥ · ∥e = supt∈R+ e−t∥u(t)∥. We define a positive cone Pe ⊂ Ce(E) by Pe = {u ∈ Ce(E) : u(t) ≥ θ, t ∈ [0,∞)}. Then, Pe is normal and Ce(E) is an ordered Banach space, whose partial order ”≤” is induced by the cone Pe. Now, we present an important result that will play an important role in the subsequent proof. Lemma 2.1 ([8]). The set Ξ ⊂ Ce([0,∞), E) is relatively compact if and only if the following conditions hold: (a) for each a > 0, the set Ξ is equicontinuous on [0, a]; (b) for any t ∈ [0,∞), Ξ(t) = {u(t) : u ∈ Ξ} is relatively compact in E; (c) limt→∞ e−t∥u(t)∥ = 0 uniformly for u ∈ Ξ. Next, let A : D(A) ⊂ E → E and −A generates an exponentially stable analytic semigroup T (t)(t ≥ 0) in E. As we all know, for a general C0-semigroup, there exist constants M ≥ 1 and ν ∈ R such that ∥T (t)∥ ≤Meνt, t ≥ 0. In particular, let growth exponent ν0 := inf{ν ∈ R : ∃M ≥ 1 such that ∥T (t)∥ ≤Meνt, t ≥ 0} < 0, the semigroup T (t)(t ≥ 0) is said to be exponentially stable. It is well known [30] that if the semigroup T (t) is continuous in the uniform operator topology for t > 0 in E, then ν0 can obtained by the spectrum σ(A) of the operator A, ν0 = − inf{Reλ | λ ∈ σ(A)}. (2.1) By Blakrishnan’s definition [4, 35], the fractional power Aβ is well defined as Aβu := sin(βπ) π ∫ ∞ 0 λβ−1(λ I +A)−1Audλ, 0 < β < 1, u ∈ D(A). (2.2) From [35] one know that −Aβ is a closed densely defined operator, which generates a bounded analytic semigroup Tβ(t)(t ≥ 0), which can be expressed as Tβ(t) = ∫ ∞ 0 gβ,t(s)T (s)ds, t > 0, EJDE-2025/44 TIME-SPACE FRACTIONAL REACTION-DIFFUSION EQUATIONS 3 where gβ,t(·) is defined by the inverse Laplace integral gβ,t(s) = 1 2πi ∫ σ+i∞ σ−i∞ ezs−tzβ dz, σ > 0, and the brach of zβ is so taken that Re(zβ) > 0 for Re(z) > 0. Moreover, one can see gβ,t(s) ≥ 0 for s > 0 and ∫∞ 0 gβ,t(s)ds = 1 in [35]. It is valuable to note that there is an important lemma about Tβ(t). Lemma 2.2 ([24]). If the semigroup T (t)(t ≥ 0) generated by −A is exponentially stable and compact, then the semigroup Tβ(t)(t ≥ 0) generated by −Aβ is exponentially stable and compact. In the following, consider a probability density function hα(τ) defined by hα(τ) = 1 πα ∞∑ n=1 (−τ)n−1Γ(nα+ 1) n! sin(nπα), τ ∈ (0,∞). Obviously, hα(τ) ≥ 0, ∫ ∞ 0 hα(τ)dτ = 1, ∫ ∞ 0 τhα(τ)dτ = 1 Γ(1 + α) , τ ∈ (0,∞). (2.3) Based on thesestatements, for t ≥ 0, we define the two operators: Jα,β(t) = ∫ ∞ 0 hα(τ)Tβ(t ατ)dτ, Kα,β(t) = α ∫ ∞ 0 τhα(τ)Tβ(t ατ)dτ. Similar to the proof in [1, 13, 32, 36], one has the following results. Lemma 2.3. The operators Jα,β(t)(t ≥ 0) and Kα,β(t)(t ≥ 0) have the following properties. (1) The operators Jα,β(t) and Kα,β(t) are strongly conntinuous operators, this indicates that for any x ∈ E and 0 ≤ t1 ≤ t2, ∥Jα,β(t2)x−Jα,β(t1)x∥ → 0 and ∥Kα,β(t2)x−Kα,β(t1)x∥ → 0 as t2 − t1 → 0. (2) Jα,β(t) and Kα,β(t) are linear bounded operators for any fixed t ∈ R+, ∥Jα,β(t)x∥ ≤M∥x∥ , ∥Kα,β(t)x∥ ≤ M Γ(α) ∥x∥. (3) Jα,β(t) and Kα,β(t) are uniformly continuous for every t > 0. (4) If semigroup Tβ(t)(t ≥ 0) is compact, then Jα,β(t) and Kα,β(t) are compact operators for every t > 0. (5) If semigroup Tβ(t)(t ≥ 0) is positive, then Jα,β(t) and Kα,β(t) are positive operators. (6) If semigroup Tβ(t)(t ≥ 0) is exponentially stable with the growth exponent −|ν0|β, then ∥Jα,β(t)∥ ≤MEα(−|ν0|βtα), ∥Kα,β(t)x∥ ≤MEα,α(−|ν0|βtα) (2.4) for every t ≥ 0, where Eα(·) and Eα,α(·) are the Mittag-Leffler functions. Lemma 2.4 ([31]). Eα(−µ) = ∫∞ 0 τhα(τ)e −µτdτ , Eα,α(−µ) = α ∫∞ 0 τhα(τ)e −µτdτ . Now, we provide a definition of S-asymptotically ω-periodic function. Let Cb([0,∞), E) denote the Banach space of all bounded and continuous functions from [0,∞) to E equipped with the norm ∥u∥C = supt∈R+ ∥u(t)∥. Definition 2.5 ([20]). A function f ∈ Cb([0,∞), E)is said to be S-asymptotically ω-periodic if there exists ω > 0 such that limt→∞ ∥f(t + ω) − f(t)∥ = 0. In this case we say that ω is an asymptotic period of f . Let SAPω(E) represent the subspace of Cb([0,∞), E) consisting of all the E-value S-asymptotically ω-periodic functions endowed with the uniform convergence norm denoted by ∥u∥C . Then SAPω(E) is a Banach space. Lemma 2.6. [27] Let Π be a convex, bounded and closed subset of a Banach space E. If Θ : Π → Π is a condensing map, then Θ has a fixed poind in Π. 4 X. ZHANG, K. DING, P. CHEN EJDE-2025/44 3. Abstract results In this section, we discuss the positive S-asymptotically ω-periodic mild solutions for the fol- lowing abstract time-space fractional evolution equations with nonlocal conditions cDα t u(t) +Aβu(t) = G(t, u(t)), t ∈ [0,+∞), u(0) = u0 + m∑ k=1 aku(Tk), (3.1) where cDα t is the Caputo fractional derivative of the order 0 < α < 1, A : D(A) ⊂ E → E is a closed linear operator and −A generates an exponentially stable analytic semigroup T (t)(t ≥ 0) in E, Aβ is the fractional power operator of A for 0 < β < 1, 0 < T1 < T2 < · · · < Tm < +∞ and ak are real numbers, G : [0,∞)× E → E is a continuous function. Definition 3.1. A function u : [0,∞) → E is said to be a mild solution of the nonlocal problem (3.1) if u ∈ C([0,∞), E) and satisfies u(t) = Jα,β(t)Λu0 + m∑ k=1 akJα,β(t)Λ ∫ Tk 0 (Tk − s)α−1Kα,β(Tk − s)G(s, u(s))ds + ∫ t 0 (t− s)α−1Kα,β(t− s)G(s, u(s))ds. (3.2) Moreover, if u(t) ≥ θ for all t ≥ 0, then it is said to be a positive mild solution of nonlocal problem (3.1). To prove the main result, we also need the following assumption: (H0) ∑m k=1 |ak| < 1 M . It follows from Lemma 2.3 (2) that ∥ ∑m k=1 akJα,β(Tk)∥ ≤ M ∑m k=1 |ak| < 1. By the operator spectral theorem, (H0) give a sufficient condition to guarantee the operator Λ on E given by Λ = ( I − m∑ k=1 akJα,β(Tk) )−1 exists and be bounded, where I is the identity operator. Indeed, by Neumann formula, Λ can be expressed by Λ = ∞∑ n=0 ( m∑ k=1 akJα,β(Tk) )n . Therefore, ∥Λ∥ ≤ ∞∑ n=0 ∥ m∑ k=1 akJα,β(Tk)∥n = 1 1− ∥ ∑m k=1 akJα,β(Tk)∥ ≤ 1 1−M ∑m k=1 |ak| . (3.3) Theorem 3.2. Let E be an ordered Banach space, whose positive cone P is normal, A : D(A) ⊂ E → E be a closed linear operator and −A generate an exponentially stable, positive, and compact analytic semigroup T (t)(t ≥ 0) in E, whose growth exponent ν0 < 0, the nonlinear function G : R+ × E → E be a continuous function. If the conditions (H0) and the following 3 conditions hold: (H1) for t ≥ 0 and x ∈ E, there exist positive constants A0 ≥ 0 and A1 ∈ (0, (1−M ∑m k=1 |ak|)|ν0|β/M) such that ∥G(t, etx)∥ ≤ A1∥x∥+A0, (H2) G is nondecreasing with respect to the second variable, i.e., for x2 ≥ x1 ≥ θ, G(t, x2) ≥ G(t, x1) ≥ θ, t ≥ 0, (H3) there exists ω > 0, for every t ∈ [0,∞), x ∈ E, lim t→∞ ∥G(t+ ω, x)−G(t, x)∥ = 0, EJDE-2025/44 TIME-SPACE FRACTIONAL REACTION-DIFFUSION EQUATIONS 5 then there exist a minimal positive S-asymptotically ω-periodic mild solution ũ of nonlocal problem (3.1). Proof. Consider the operator Θ on Ce(E) defined by (Θu)(t) = Jα,β(t)Λu0 + ∫ t 0 (t− s)α−1Kα,β(t− s)G(s, u(s))ds + m∑ k=1 akJα,β(t)Λ ∫ Tk 0 (Tk − s)α−1Kα,β(Tk − s)G(s, u(s))ds. (3.4) By (3.3), (3.4) and (H1), one can conclude that e−t∥(Θu)(t)∥ ≤ e−t∥Jα,β(t)Λu0∥+ e−t ∫ t 0 (t− s)α−1∥Kα,β(t− s)∥∥G(s, u(s))∥ds + e−t m∑ k=1 |ak|∥Jα,β(t)∥∥Λ∥ ∫ Tk 0 (Tk − s)α−1∥Kα,β(Tk − s)∥∥G(s, u(s))∥ds ≤ e−tM∥u0∥ 1−M ∑m k=1 |ak| + e−tM ∑m k=1 |ak| 1−M ∑m k=1 |ak| × αM ∫ Tk 0 ∫ ∞ 0 τhα(τ)(Tk − s)α−1e−|ν0|β(Tk−s)ατ (A1∥u∥e +A0)dτds + e−tαM ∫ t 0 ∫ ∞ 0 τhα(τ)(t− s)α−1e−|ν0|β(t−s)ατ (A1∥u∥e +A0)dτds ≤ e−tM∥u0∥ 1−M ∑m k=1 |ak| + e−tM ∑m k=1 |ak| 1−M ∑m k=1 |ak| M(A1∥u∥e +A0) ∫ ∞ 0 hα(τ)dτ ∫ ∞ 0 e−|ν0|βsds + e−tM(A1∥u∥e +A0) ∫ ∞ 0 hα(τ)dτ ∫ ∞ 0 e−|ν0|βsds ≤ e−tM∥u0∥ 1−M ∑m k=1 |ak| + e−tM ∑m k=1 |ak| 1−M ∑m k=1 |ak| M(A1∥u∥e +A0) |ν0|β + e−tM(A1∥u∥e +A0) |ν0|β ≤ e−tM∥u0∥ 1−M ∑m k=1 |ak| + e−t ( M ∑m k=1 |ak| 1−M ∑m k=1 |ak| + 1 )M(A1∥u∥e +A0) |ν0|β ≤ e−tM∥u0∥ 1−M ∑m k=1 |ak| + e−tM(A1∥u∥e +A0)( 1−M ∑m k=1 |ak| ) |ν0|β . (3.5) Thus, we can conclude that ∥(Θu)(t)∥e ≤ M∥u0∥ 1−M ∑m k=1 |ak| + M(A1∥u∥e +A0) (1−M ∑m k=1 |ak|)|ν0|β := φ+ ψ∥u∥e, (3.6) where φ = |ν0|βM∥u0∥+MA0 (1−M ∑m k=1 |ak|)|ν0|β , ψ = MA1 (1−M ∑m k=1 |ak|)|ν0|β are positive with ψ < 1. Hence, limt→∞ e−t∥(Θu)(t)∥ = 0, which implies that Θ : Ce(E) → Ce(E) is well defined. Next we prove that Θ is continuous on Ce(E). Let {un} ⊂ Ce(E) such that un → u as n→ ∞ in Ce(E). From the continuity of G, it can be obtained that sup s∈[0,∞) ∥G ( s, un(s) ) −G ( s, u(s) ) ∥ → 0 as n→ ∞. Then by the Lebesgue dominated convergence theorem, ∥(Θun)(t)− (Θu)(t)∥ 6 X. ZHANG, K. DING, P. CHEN EJDE-2025/44 ≤M m∑ k=1 |ak|∥Λ∥ ∫ Tk 0 (Tk − s)α−1∥Kα,β(Tk − s)∥∥G(s, un(s))−G(s, u(s))∥ds + ∫ t 0 (t− s)α−1∥Kα,β(Tk − s)∥∥G(s, un(s))−G(s, u(s))∥ds ≤ M ∑m i=1 |ak| 1−M ∑m k=1 |ak| M ∫ ∞ 0 hα(τ)dτ ∫ ∞ 0 e−|ν0|βs∥G(s, un(s))−G(s, u(s))∥ds +M ∫ ∞ 0 hα(τ)dτ ∫ ∞ 0 e−|ν0|βs∥G(s, un(s))−G(s, u(s))∥ds ≤ M( 1−M ∑m k=1 |ak| ) |ν0|β sup s∈[0,∞) ∥G(s, un(s))−G(s, u(s))∥ → 0 as n→ ∞. Hence, ∥(Θun)(t)− (Θu)(t)∥e = sup t∈[0,∞) e−t∥(Θun)(t)− (Θu)(t)∥ → 0 (n→ ∞), which implies that Θ : Ce(E) → Ce(E) is a continuous operator. Therefore, one can deduced that the fixed points of Θ are mild solutions to nonlocal problem (3.1). Based on this fact, we first prove that Θ(SAPω(E)) ⊂ SAPω(E). For any ϵ > 0 and u ∈ SAPω(E), there exists a constant t1ϵ > 0, for t ≥ t1ϵ , have ∥u(t+ω)− u(t)∥ ≤ ϵ. On the one hand, by continuity of G, for t > t1ϵ , ∥G(t, u(t+ ω))−G(t, u(t))∥ ≤ |ν0|β M ϵ. (3.7) On the other hand, by (H3), there exists a constant t2ϵ such that for t > t2ϵ , ∥G(t+ ω, u(t+ ω))−G(t, u(t+ ω))∥ ≤ |ν0|β M ϵ. (3.8) According to (2.4), we let M0 =M max { sup t≥0 Eα(−|ν0|βtα)(1 + t)α, sup t≥0 Eα,α(−|ν0|βtα)(1 + t)2α } , then ∥Jα,β(t)∥ ≤ M0 (1 + t)α , ∥Kα,β(t)∥ ≤ M0 (1 + t)2α , t ≥ 0. (3.9) Hence, for t > max{t1ϵ , t2ϵ}, it follows from (3.4) that (Θu)(t+ ω)− (Θu)(t) = 4∑ i=1 Bi(t), where B1(t) = ( Jα,β(t+ ω)− Jα,β(t) ) ( Λu0 + m∑ k=1 akΛ ∫ Tk 0 (Tk − s)α−1Kα,β(Tk − s)G(s, u(s))ds ) , B2(t) = ∫ ω 0 (t+ ω − s)α−1Kα,β(t+ ω − s)G(s, u(s))ds, B3(t) = ∫ t 0 (t− s)α−1Kα,β(t− s) ( G(s, u(s+ ω))−G(s, u(s)) ) ds, B4(t) = ∫ t 0 (t− s)α−1Kα,β(t− s) ( G(s+ ω, u(s+ ω))−G(s, u(s+ ω)) ) ds. EJDE-2025/44 TIME-SPACE FRACTIONAL REACTION-DIFFUSION EQUATIONS 7 This implies that ∥(Θu)(t+ ω)− (Θu)(t)∥ ≤ 4∑ i=1 ∥Bi(t)∥. Let us start with estimations of ∥B1(t)∥ and ∥B2(t)∥. By (3.9), one can see that ∥B1(t)∥ = ∥ ( Jα,β(t+ ω)− Jα,β(t) ) ∥∥Λu0 + m∑ k=1 |ak|Λ ∫ Tk 0 (Tk − s)α−1Kα,β(Tk − s)G(s, u(s))ds∥ ≤ 2M0 (1 + t)α ( ∥Λu0∥+ ∥Λ∥ m∑ k=1 |ak| ∫ Tk 0 (Tk − s)α−1∥Kα,β(Tk − s)∥∥G(s, u(s))∥ds ) and ∥B2(t)∥ = ∥ ∫ ω 0 (t+ ω − s)α−1Kα,β(t+ ω − s)G(s, u(s))ds∥ ≤ ∫ ω 0 (t+ ω − s)α−1∥Kα,β(t+ ω − s)∥∥G(s, u(s))∥ds ≤ ∫ ω 0 (t+ ω − s)α−1 (A1∥u(s)∥+A0)M0 (1 + t+ ω − s)2α ds ≤ (A1∥u∥C +A0) M0((t+ ω)α − tα) α(1 + t)2α ≤ (A1∥u∥C +A0) M0ω α α(1 + t)2α . By (H1), (3.7) and (3.9), one can obtain that ∥B3(t)∥ = ∥ ∫ tϵ 0 (t− s)α−1Kα,β(t− s) ( G(s, u(s+ ω))−G(s, u(s)) ) ds∥ + ∥ ∫ t tϵ (t− s)α−1Kα,β(t− s) ( G(s, u(s+ ω))−G(s, u(s)) ) ds∥ ≤ ∫ tϵ 0 (t− s)α−1∥Kα,β(t− s)∥∥G(s, u(s+ ω))−G(s, u(s))∥ds + ∫ t tϵ (t− s)α−1∥Kα,β(t− s)∥∥G(s, u(s+ ω))−G(s, u(s))∥ds ≤ 2M0 ∫ tϵ 0 (t− s)α−1 (1 + t− s)2α (A1∥u(s)∥+A0)ds + ∫ t 0 (t− s)α−1∥Kα,β(t− s)∥ds |ν0| β M ϵ ≤ 2M0(A1∥u∥C +A0) (t− tϵ) −α − t−α α +Mα ∫ t 0 ((t− s)α−1 ∫ ∞ 0 τhα(τ)e −|ν0|β(t−s)ατdτ)ds |ν0|β M ϵ ≤ 2M0(A1∥u∥C +A0) (t− tϵ) −α − t−α α + ϵ, which implies that ∥B3(t)∥ tend to 0 as t→ ∞. Similarly, By (H1), (3.8) and (3.9), we can get that ∥B4(t)∥ tend to 0 as t→ ∞. Summing up, it follows from above results for ∥Bi(t)∥(i = 1, 2, 3, 4) that Θu ∈ SAPω(E), which justifies the following inclusion, that is Θ(SAPω(E)) ⊂ SAPω(E). 8 X. ZHANG, K. DING, P. CHEN EJDE-2025/44 In what follows, we prove the existence of positive solutions by a monotone iterative technique. For any u, v ∈ Pe with u ≤ v, by (H2), (3.4), u0 ≥ θ, the positivity of Jα,β(t) and Kα,β(t), one can find that for all t ∈ [0,∞), θ ≤ (Θu)(t) ≤ (Θv)(t). Thus Θ is a monotonically increasing operator. Let v0 = θ ∈ Pe ∩ SAPω(E) and define a sequence {vn} by vn = Θvn−1, n = 1, 2, . . . . (3.10) It follows from the monotonicity of Θ, (3.6) and (3.10) that {vn} ⊂ Pe ∩ SAPω(E) and v0 ≤ v1 ≤ · · · ≤ vn ≤ . . . , (3.11) ∥vn∥e ≤ φ+ ψ∥vn−1∥e. (3.12) Since ∥v0∥e ≡ 0, by (3.12), one can find that ∥vn∥e ≤ φ+ φψ + φψ2 + · · ·+ φψn−1 = φ 1− ψn 1− ψ ≤ φ 1− ψ , (3.13) which implies that the sequence {vn} is uniformly bounded. At this level, we verify that the sequence {vn} is uniformly convergent. Next, suppose that 0 < a < +∞ is an arbitrary constant, we need to verify {vn} ⊂ Pe∩SAPω(E) is locally equicontinuous in [0, a]. For any u ∈ {vn} and 0 ≤ t1 ≤ t2 ≤ a, a direct computation allows us to obtain ∥(Θu)(t2)− (Θu)(t1)∥ ≤ 5∑ i=1 Di, where D1 = ∥Jα,β(t2)Λu0 − Jα,β(t1)Λu0∥, D2 = ∥Jα,β(t2)− Jα,β(t1)∥ m∑ k=1 |ak|∥Λ∥ ∫ Tk 0 (Tk − s)α−1∥Kα,β(Tk − s)∥∥G(s, u(s))∥ds, D3 = ∫ t1 0 ((t2 − s)α−1 − (t1 − s)α−1)∥Kα,β(t2 − s)∥∥G(s, u(s))∥ds, D4 = ∫ t1 0 (t1 − s)α−1∥Kα,β(t2 − s)− Kα,β(t1 − s)∥∥G(s, u(s))∥ds, D5 = ∫ t2 t1 (t2 − s)α−1∥Kα,β(t2 − s)∥∥G(s, u(s))∥ds. We just need to examine that Di tend to 0 independently of u ∈ {vn} as t2 − t1 → 0 for i = 1, 2, 3, 4, 5. Thus, by Lemma 2.3, we obtain D1 = ∥Jα,β(t2)Λu0 − Jα,β(t1)Λu0∥ ≤ ∥Jα,β(t2)− Jα,β(t1)∥∥Λ∥∥u0∥ → 0 as t2 − t1 → 0. Similarly, D2 ≤ ∥Jα,β(t2)− Jα,β(t1)∥ m∑ k=1 |ak|∥Λ∥ ∫ Tk 0 (Tk − s)α−1∥Kα,β(Tk − s)∥∥G(s, u(s))∥ds → 0 ast2 − t1 → 0. For D3, it follows from (H1) and (3.13) that D3 = ∫ t1 0 ((t2 − s)α−1 − (t1 − s)α−1)∥Kα,β(t2 − s)∥∥G(s, u(s))∥ds ≤ M Γ(α+ 1) ( A1 φ 1− ψ +A0 ) (tα1 − tα2 + (t2 − t1) α) EJDE-2025/44 TIME-SPACE FRACTIONAL REACTION-DIFFUSION EQUATIONS 9 ≤ M Γ(α+ 1) ( A1 φ 1− ψ +A0 ) (t2 − t1) α → 0 a st2 − t1 → 0. For t1 = 0 and t2 > 0, it is conspicuous that D4 = 0. Now, for t1 > 0 and ϵ > 0 small enough, by (H1), (3.13) and Lemma 2.3(2), we obtain D4 ≤ ∫ t1−ε 0 (t1 − s)α−1∥(Kα,β(t2 − s)− Kα,β(t1 − s))∥∥G(s, u(s))∥ds + ∫ t1 t1−ε (t1 − s)α−1∥(Kα,β(t2 − s)− Kα,β(t1 − s))∥∥G(s, u(s))∥ds ≤ (A1 φ 1− ψ +A0) sup s∈[0,t1−ε] ∥(Kα,β(t2 − s)− Kα,β(t1 − s))∥ ∫ t1−ε 0 (t1 − s)α−1ds + 2M Γ(α) (A1 φ 1− ψ +A0) ∫ t1 t1−ε (t1 − s)α−1ds ≤ (A1 φ 1− ψ +A0) ( sup s∈[0,t1−ε] ∥(Kα,β(t2 − s)− Kα,β(t1 − s))∥ t α 1 − εα α + 2M Γ(α+ 1) εα ) → 0 as t2 − t1 → 0, ϵ→ 0. For D5, we observe that D5 ≤ ∫ t2 t1 (t2 − s)α−1∥Kα,β(t2 − s)∥∥G(s, u(s))∥ds ≤ M Γ(α+ 1) (A1 φ 1− ψ +A0)(t2 − t1) α → 0 as t2 − t1 → 0. Combining all the above arguments, one can deduced that ∥(Θu)(t2)− (Θu)(t1)∥ → 0 as t2 − t1 → 0, which means that the operator Θ is locally equicontinuous in [0, a] for arbitrary constant 0 < a < +∞. Subsequently, we need to prove {vn(t)} is relatively compact on E for t ∈ [0,∞). Let V = {vn} and V0 = V ∪ {v0}. Obviously, V(t) = (ΘV0)(t) for t ∈ [0,∞). It is easy to prove that {vn(0)} is relatively compact on E. We only consider the case t > 0, for all ∀ϵ ∈ (0, t) and δ > 0, define Θϵ,δvn by (Θϵ,δvn)(t) = Jα,β(t)Λvn−1(0) + α m∑ k=1 akΛJα,β(t) × ∫ Tk 0 ∫ ∞ 0 (Tk − s)α−1τhα(τ)Tβ((Tk − s)ατ)G(s, vn−1(s))dτds + α ∫ t−ϵ 0 ∫ ∞ δ (t− s)α−1τhα(τ)Tβ((t− s)ατ)G(s, vn−1(s))dτds = Jα,β(t)Λvn−1(0) + α m∑ k=1 akΛJα,β(t) × ∫ Tk 0 ∫ ∞ 0 (Tk − s)α−1τhα(τ)Tβ((Tk − s)ατ)G(s, vn−1(s))dτds + αTβ(ϵ αδ) ∫ t−ϵ 0 ∫ ∞ δ (t− s)α−1τhα(τ)Tβ((t− s)ατ − ϵαδ)G(s, vn−1(s))dτds. 10 X. ZHANG, K. DING, P. CHEN EJDE-2025/44 The compactness of Jα,β(t) and Tβ(ϵ αδ) implies that the set (Θϵ,δV0)(t) is relatively compact in E. Moreover, for ∀vn ∈ V0 and t ∈ (0,∞), one can obtain that ∥(Θvn)(t)− (Θϵ,δvn)(t)∥ = ∥α ∫ t 0 ∫ δ 0 (t− s)α−1τhα(τ)Tβ((t− s)ατ)G(s, vn−1(s))dτds∥ + ∥α ∫ t t−ϵ ∫ ∞ δ (t− s)α−1τhα(τ)Tβ((t− s)ατ)G(s, vn−1(s))dτds∥ ≤ ( A1 φ 1− ψ +A0 ) α ∫ t 0 ∫ δ 0 (t− s)α−1τhα(τ)∥Tβ((t− s)ατ)∥dτds + ( A1 φ 1− ψ +A0 ) α ∫ t t−ϵ ∫ ∞ δ (t− s)α−1τhα(τ)∥Tβ((t− s)ατ)∥dτds ≤M(A1 φ 1− ψ +A0) · (∫ t 0 (t− s)α−1ds ∫ δ 0 τhα(τ)dτ + ∫ t t−ϵ (t− s)α−1ds ∫ ∞ δ τhα(τ)dτ ) → 0 as ϵ→ 0, δ → 0. We conclude that there is a relatively compact set (Θϵ,δV0)(t) arbitrarily close to the set (ΘV0)(t) on E for t ∈ (0,∞). Consequently, we can obtain that {vn(t)} is relatively compact on E for t ∈ [0,∞). Further, for any u ∈ {vn}, by (3.5) and (3.13), we can easily get that lim t→∞ e−t∥(Θu)(t)∥ = 0. Hence, it follows from Lemma 2.1 that {vn} is relatively compact in Pe ∩ SAPω(E). Hence, there exist convergent subsequence in {vn}. As a result, one can obtain that {vn} itself is uniformly convergent through the monotonicity of sequence and the normality of cone, which means that there exist ũ ∈ Pe ∩ SAPω(E) such that limn→∞ vn = ũ. Moreover, taking the limit in (3.10), we can obtain ũ = Θũ. Therefore, ũ ∈ Pe ∩ SAPω(E) is fixed point of Θ, which is a positive S-asymptotically ω-periodic mild solution of nonlocal problem (3.1). We need to verify that ũ is the minimal positive S-asymptotically ω-periodic mild solution. Let û ∈ Pe ∩ SAPω(E) be a positive S-asymptotically ω-periodic mild solution of nonlocal problem (3.1), which means that û(t) = Θû(t) for every t ∈ [0,∞). Obviously, û(t) ≥ v0 = 0. Taking into account the monotonicity of Θ, one can deduced that û(t) = (Θû)(t) ≥ (Θv0)(t) = v1(t), (3.14) it follows that û > v1. Repeat this process, one can see û > vn, n = 1, 2, . . . . It’s worth noting that one can obtain û > ũ through taking the limit in (3.14) as n → ∞, which means that ũ is the minimal positive S-asymptotically ω-periodic mild solution of nonlocal problem (3.1). This completes the proof of Theorem 3.2. □ Now, we assume that the cone P is a regeneration cone on E and T (t)(t ≥ 0) generated by −A is a positive semigroup, it follows that λ0I+A has positive bounded inverse operator (λ0I+A) −1 if λ0 > − inf{Reλ | λ ∈ σ(A)} is sufficiently large through the characteristic of positive semigroups. Since σ(A) ̸= ∅, the spectral radius r((λ0I +A)−1) = 1 dist(−λ0, σ(A)) > 0. Based on the famous Krein-Rutman theorem(see [15, 16]), A has the first eigenvalue λ1 > 0, associated a positive eigenfunction e1, and λ1 = inf{Reλ | λ ∈ σ(A)}. Therefore, it follows from (2.1) that ν0 = −λ1. By Theorem (3.2), we have the following results. EJDE-2025/44 TIME-SPACE FRACTIONAL REACTION-DIFFUSION EQUATIONS 11 Corollary 3.3. Let E be an ordered Banach space, whose positive cone P is a regeneration cone, let A : D(A) ⊂ E → E be a closed linear operator and −A generate an exponentially stable, positive, and compact semigroup T (t)(t ≥ 0) in E, u0 ≥ θ. Assume that G : [0,∞)× E → E is a continuous function, and let conditions (H0), (H2), (H3), and (H4) for t ≥ 0 and x ∈ E, there exist positive constants A0 ≥ 0 and A1 ∈ (0, (1−M ∑m k=1 |ak|)λ β 1/M) such that ∥G(t, etx)∥ ≤ A1∥x∥+A0, hold, then there exist a minimal positive S-asymptotically ω-periodic mild solution ũ of nonlocal problem (3.1). Theorem 3.4. Let E be an ordered Banach space, whose positive cone P is normal, A : D(A) ⊂ E → E be a closed linear operator and −A generate an exponentially stable, positive and compact analytic semigroup T (t)(t ≥ 0) in E, whose growth exponent ν0 < 0, the nonlinear function G : R+ × E → E be a continuous mapping. If the conditions (H0),(H3),(H4)and (H5) for each u ∈ Ce(E) with u(t) ≥ ςe1, there is a constant ς > 0 such that G(t, u(t)) ≥ G(t, ςe1) ≥ λβ1 ςe1, hold and u(0) ≥ ςe1, then the nonlocal problem (3.1) has at least one positive S-asymptotically ω-periodic mild solution. Proof. Let Θ be defined by (3.4), it follows from the proof of Theorem (3.2) that Θ(SAPω(E)) ⊂ SAPω(E). We denote BR0 := {u ∈ Ce(E) | ∥u∥e ≤ R0, u(t) ≥ ςe1, t ≥ 0} (3.15) which is a nonempty bounded convex closed set for R0 ≥ M(λβ1∥u0∥+A0)( 1−M ∑m k=1 |ak| ) λβ1 −MA1 . Hence, for any u ∈ BR0 and t ≥ 0, exploiting (H4), according to e−t ≤ 1, one can obtain ∥(Θu)(t)∥e = sup t∈R+ e−t∥(Θu)(t)∥ ≤ ∥(Θu)(t)∥ ≤ M∥u0∥ 1−M ∑m k=1 |ak| + M(A1∥u∥e +A0) (1−M ∑m k=1 |ak|)λ β 1 ≤ R0. Let w0 = ςe1. Then w0(t) = ςe1 for any t ≥ 0, and η(t) :=c Dα t w0(t) +Aβw0(t) = λβ1 ςe1 ≤ G(t, ςe1), t ≥ 0. By the positivity of semigroup Tβ(t)(t ≥ 0), condition (H5) and (3.4), for any u ∈ BR0 and t ≥ 0, one can see that ςe1 = w0(t) = Jα,β(t)Λw0(0) + m∑ k=1 akJα,β(t)Λ ∫ Tk 0 (Tk − s)α−1Kα,β(Tk − s)η(s)ds + ∫ t 0 (t− s)α−1Kα,β(t− s)η(s)ds ≤ Jα,β(t)Λςe1 + m∑ k=1 akJα,β(t)Λ ∫ Tk 0 (Tk − s)α−1Kα,β(Tk − s)G(s, ςe1)ds + ∫ t 0 (t− s)α−1Kα,β(t− s)G(s, ςe1)ds 12 X. ZHANG, K. DING, P. CHEN EJDE-2025/44 ≤ Jα,β(t)Λu0 + m∑ k=1 akJα,β(t)Λ ∫ Tk 0 (Tk − s)α−1Kα,β(Tk − s)G(s, u(s))ds + ∫ t 0 (t− s)α−1Kα,β(t− s)G(s, u(s))ds = (Θu)(t). Thus, Θ(BR0 ) ⊂ BR0 and (Θu)(t) ≥ ςe1 for any u ∈ BR0 and t ≥ 0. Next, we prove that Θ : BR0 → BR0 is a completely continuous operator. From assumptions (H3) and (H4), there is a constant W such that for all u ∈ BR0 , sup t∈[0,∞) ∥G(t, u(t))∥ ≤ W. (3.16) It should be noted that the set Θ(BR0 ) is locally equicontinuous on E by using the method similar to Theorem (3.2) and for any u ∈ BR0 , lim t→∞ e−t∥(Θu)(t)∥ = 0. So we only need to show that for any t ∈ [0,∞), {(Θu)(t) | u ∈ BR0 } is relatively compact in E. Obviously, {(Θu)(0) : u ∈ BR0} is relatively compact in E. We only consider the case t > 0, for all δ > 0 and ϵ ∈ (0, t), define (Θϵ,δu) by (Θϵ,δu)(t) = Jα,β(t)Λu0 + α m∑ k=1 akΛJα,β(t) × ∫ Tk 0 ∫ ∞ 0 (Tk − s)α−1τhα(τ)Tβ((Tk − s)ατ)G(s, u(s))dτds + α ∫ t−ϵ 0 ∫ ∞ δ (t− s)α−1τhα(τ)Tβ((t− s)ατ)G(s, u(s))dτds = Jα,β(t)Λu0 + α m∑ k=1 akΛJα,β(t) × ∫ Tk 0 ∫ ∞ 0 (Tk − s)α−1τhα(τ)Tβ((Tk − s)ατ)G(s, u(s))dτds + αTβ(ϵ αδ) ∫ t−ϵ 0 ∫ ∞ δ (t− s)α−1τhα(τ)Tβ((t− s)ατ − ϵαδ)G(s, u(s))dτds. From the compactness of Jα,β(t) and Tβ(ϵ αδ), one gets that {(Θϵ,δu)(t) | u ∈ BR0} is relatively compact in E. Thus, for every u ∈ BR0 , it follows from (3.16) that ∥(Θu)(t)− (Θϵ,δu)(t)∥ = ∥α ∫ t 0 ∫ δ 0 (t− s)α−1τhα(τ)Tβ((t− s)ατ)G(s, u(s))dτds∥ + ∥α ∫ t t−ϵ ∫ ∞ δ (t− s)α−1τhα(τ)Tβ((t− s)ατ)G(s, u(s))dτds∥ ≤ W ∫ t 0 ∫ δ 0 (t− s)α−1τhα(τ)∥Tβ((t− s)ατ)∥dτds +W ∫ t t−ϵ ∫ ∞ δ (t− s)α−1τhα(τ)∥Tβ((t− s)ατ)∥dτds ≤MW ∫ t 0 (t− s)α−1ds ∫ δ 0 τhα(τ)dτ +MW ∫ t t−ϵ (t− s)α−1ds ∫ ∞ δ τhα(τ)dτ → 0 as ϵ→ 0, δ → 0, which implies that there is a relatively compact set {(Θϵ,δu)(t) | u ∈ BR0 } arbitrarily close to the set {(Θu)(t) | u ∈ BR0 } in E for t ∈ (0,∞). Therefore, the set {(Θu)(t) | u ∈ BR0 } is relatively EJDE-2025/44 TIME-SPACE FRACTIONAL REACTION-DIFFUSION EQUATIONS 13 compact on E for t ∈ [0,∞). Moreover, it follows from Lemma 2.1 that Θ(BR0 ) is relatively compact in Ce(E). Based on above results, one can find that Θ : BR0 ∩ SAPω(E) → BR0 ∩ SAPω(E) is a com- pletely continuous operator, which implies that Θ is a condensing mapping from BR0 ∩ SAPω(E) into BR0 ∩ SAPω(E). Therefore, Lemma 2.6 implies that Θ has a fixed point ũ ∈ BR0 ∩ SAPω(E). We need to verify that ũ ∈ SAPω(E). Let {un} ⊂ BR0 ∩ SAPω(E) converge to ũ, it follows from the continuity of Θ and (3.15) that {Θun} converges to Θũ = ũ uniformly in [0,∞) and ũ ≥ ςe1, which implies that ũ ∈ SAPω(E) is a positive S-asymptotically ω-periodic mild solution of nonlocal problem (3.1). This completes the proof of Theorem 3.4. □ 4. Application to nonlocal problem (1.1) Let E = L2(Ω) with the L2-norm ∥ · ∥2 and partial order ≤, P = {u ∈ L2(Ω) | u(x) ≥ 0, a.e.x ∈ Ω} is a normal cone in L2(Ω), then P is a regular cone of E. We define the operator A : D(A) ⊂ E → E as follows: D(A) =W 2,2(Ω) ∩W 1,2 0 (Ω), Au = −∆u. (4.1) Let u(t, x) = u(t)(x) and F (t, u(t, x)) = G(t, u(t))(x), u0 + m∑ k=1 aku(Tk, x) = u0 + m∑ k=1 aku(Tk)(x). (4.2) Then the nonlocal problem (1.1) can be rewritten as an abstract evolution equation with nonlocal conditions (3.1) in L2(Ω). According to (2.2), the fractional Laplacian is well defined. Besides, if λn(n = 1, 2 . . . ) are the eigenvalues of −∆ with homogeneous Dirichlet boundary conditions cnsidered in L2(Ω) and en as its corresponding eigenfuction, it follows that (−∆)βen = λβnen, x ∈ Ω, e ∣∣ ∂Ω = 0, which λn = n2π2 and corresponding eigenfunctions en(x) = √ 2 sin(nπx), n = 1, 2 . . . . Hence, based on Corollary 3.3 and Theorem 3.4, we can establish the following results. Theorem 4.1. Let nonlinear function F : [0,∞) × P → P be a continuous mapping. If the followinf 4 conditions hold: (K0) ∑m k=1 |ak| < 1, (K1) there are nonnegative constants A1 ∈ (0, (1− ∑m k=1 |ak|)π2β), A0 ≥ 0 and a nondecreasing function et ∈ C(R+, [1,∞)) with limt→∞ et = +∞ such that ∥F (t, etξ)∥2 ≤ A1∥ξ∥2 +A0, t ≥ 0, ξ ∈ E, (K2) for any ξ1, ξ2 ∈ E with ξ2 ≥ ξ1 ≥ θ, F (t, ξ2) ≥ F (t, ξ1) ≥ θ, t ≥ 0, (K3) there exist ω > 0 such that lim t→∞ ∥F (t+ ω, ξ)− F (t, ξ)∥2 = 0, ξ ∈ E, t ≥ 0, then nonlocal problem (1.1) exist a minimal positive S-asymptotically ω-periodic solution. Proof. From [2] one can see −A generates a uniformly bounded analytic semigroup T (t)(t ≥ 0) in E , and T (t)(t ≥ 0) is contractive in E means that ∥T (t)∥ ≤ 1 for t ≥ 0. In addition, from [28] the operator A has compact resolvent in L2(Ω) implies that the semigroup T (t)(t ≥ 0) is compact. Besides, λI + A has a positive bounded inverse operator (λI + A)−1 for λ > 0 implies that T (t)(t ≥ 0) is a positive semigroup. Therefore, based on the argument in preliminaries and the properties of the semigroup T (t)(t ≥ 0) generated by −A, one can deduce that the analytic semigroup Tβ(t)(t ≥ 0) generated by −Aβ is compact, positive and exponentially stable on E as well as ∥Tβ(t)∥ ≤ 1 for all t ≥ 0. Let M = 1 and ν0 = −λ1 = −π2, by conditions (K0) and (K1), we can deduced that conditions (H0) and (H4) hold. From the conditions (K2) and (K3), we can deduced that conditions (H2) and (H3) hold. Thus, by Corrollary 3.3 one can deduced that nonlocal problem (1.1) exist a minimal positive S-asymptotically ω-periodic solution. □ 14 X. ZHANG, K. DING, P. CHEN EJDE-2025/44 Based on the proof of this theorem, it is not difficult to obtain the following result. Theorem 4.2. Let nonlinear function F : [0,∞) × P → P be a continuous mapping. 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Xuping Zhang (corresponding author) Department of Mathematics, Northwest Normal University, Lanzhou 730070, China Email address: lanyu9986@126.com Kaibo Ding Department of Mathematics, Northwest Normal University, Lanzhou 730070, China Email address: dingkb583x@163.com Pengyu Chen Department of Mathematics, Northwest Normal University, Lanzhou 730070, China. Gansu Provincial Research Center for Basic Disciplines of Mathematics and Statistics, Lanzhou 730070, China Email address: chpengyu123@163.com 1. Introduction 2. Preliminaries 3. Abstract results 4. Application to nonlocal problem (1.1) Acknowledgments References