id	sid	tid	token	lemma	pos
elements-9064	1	1	restriction	restriction	NOUN
elements-9064	1	2	factors	factor	NOUN
elements-9064	1	3	are	be	AUX
elements-9064	1	4	implicated	implicate	VERB
elements-9064	1	5	in	in	ADP
elements-9064	1	6	long	long	ADJ
elements-9064	1	7	-	-	PUNCT
elements-9064	1	8	term	term	NOUN
elements-9064	1	9	evolutionary	evolutionary	ADJ
elements-9064	1	10	“	"	PUNCT
elements-9064	1	11	arms	arm	NOUN
elements-9064	1	12	races	race	NOUN
elements-9064	1	13	,	,	PUNCT
elements-9064	1	14	”	"	PUNCT
elements-9064	1	15	in	in	ADP
elements-9064	1	16	which	which	PRON
elements-9064	1	17	viral	viral	ADJ
elements-9064	1	18	antagonists	antagonist	NOUN
elements-9064	1	19	drive	drive	VERB
elements-9064	1	20	the	the	DET
elements-9064	1	21	evolution	evolution	NOUN
elements-9064	1	22	of	of	ADP
elements-9064	1	23	host	host	NOUN
elements-9064	1	24	proteins	protein	NOUN
elements-9064	1	25	,	,	PUNCT
elements-9064	1	26	and	and	CCONJ
elements-9064	1	27	vice	vice	ADV
elements-9064	1	28	versa	versa	ADV
elements-9064	1	29	.	.	PUNCT
elements-9064	2	1	consequently	consequently	ADV
elements-9064	2	2	,	,	PUNCT
elements-9064	2	3	restriction	restriction	NOUN
elements-9064	2	4	factors	factor	NOUN
elements-9064	2	5	are	be	AUX
elements-9064	2	6	remarkably	remarkably	ADV
elements-9064	2	7	variable	variable	ADJ
elements-9064	2	8	,	,	PUNCT
elements-9064	2	9	displaying	display	VERB
elements-9064	2	10	polymorphism	polymorphism	NOUN
elements-9064	2	11	within	within	ADP
elements-9064	2	12	species	specie	NOUN
elements-9064	2	13	and	and	CCONJ
elements-9064	2	14	divergence	divergence	NOUN
elements-9064	2	15	between	between	ADP
elements-9064	2	16	species	specie	NOUN
elements-9064	2	17	as	as	ADP
elements-9064	2	18	a	a	DET
elements-9064	2	19	result	result	NOUN
elements-9064	2	20	of	of	ADP
elements-9064	2	21	positive	positive	ADJ
elements-9064	2	22	selection	selection	NOUN
elements-9064	2	23	.	.	PUNCT
elements-9064	3	1	this	this	DET
elements-9064	3	2	paper	paper	NOUN
elements-9064	3	3	investigates	investigate	VERB
elements-9064	3	4	diversity	diversity	NOUN
elements-9064	3	5	in	in	ADP
elements-9064	3	6	the	the	DET
elements-9064	3	7	apobec3f	apobec3f	PROPN
elements-9064	3	8	(	(	PUNCT
elements-9064	3	9	a3f	a3f	ADJ
elements-9064	3	10	)	)	PUNCT
elements-9064	3	11	restriction	restriction	NOUN
elements-9064	3	12	factors	factor	NOUN
elements-9064	3	13	of	of	ADP
elements-9064	3	14	old	old	ADJ
elements-9064	3	15	world	world	NOUN
elements-9064	3	16	primates	primate	NOUN
elements-9064	3	17	in	in	ADP
elements-9064	3	18	order	order	NOUN
elements-9064	3	19	to	to	PART
elements-9064	3	20	determine	determine	VERB
elements-9064	3	21	whether	whether	SCONJ
elements-9064	3	22	they	they	PRON
elements-9064	3	23	display	display	VERB
elements-9064	3	24	evidence	evidence	NOUN
elements-9064	3	25	of	of	ADP
elements-9064	3	26	involvement	involvement	NOUN
elements-9064	3	27	in	in	ADP
elements-9064	3	28	an	an	DET
elements-9064	3	29	evolutionary	evolutionary	ADJ
elements-9064	3	30	“	"	PUNCT
elements-9064	3	31	arms	arm	NOUN
elements-9064	3	32	race	race	NOUN
elements-9064	3	33	.	.	PUNCT
elements-9064	3	34	”	"	PUNCT
elements-9064	4	1	we	we	PRON
elements-9064	4	2	speculated	speculate	VERB
elements-9064	4	3	that	that	SCONJ
elements-9064	4	4	genetic	genetic	ADJ
elements-9064	4	5	variability	variability	NOUN
elements-9064	4	6	in	in	ADP
elements-9064	4	7	a3f	a3f	PROPN
elements-9064	4	8	could	could	AUX
elements-9064	4	9	reflect	reflect	VERB
elements-9064	4	10	evolutionary	evolutionary	ADJ
elements-9064	4	11	conflict	conflict	NOUN
elements-9064	4	12	with	with	ADP
elements-9064	4	13	the	the	DET
elements-9064	4	14	vif	vif	NOUN
elements-9064	4	15	proteins	protein	NOUN
elements-9064	4	16	of	of	ADP
elements-9064	4	17	primate	primate	NOUN
elements-9064	4	18	lentiviruses	lentiviruse	NOUN
elements-9064	4	19	,	,	PUNCT
elements-9064	4	20	which	which	PRON
elements-9064	4	21	are	be	AUX
elements-9064	4	22	known	know	VERB
elements-9064	4	23	to	to	PART
elements-9064	4	24	enhance	enhance	VERB
elements-9064	4	25	viral	viral	ADJ
elements-9064	4	26	replication	replication	NOUN
elements-9064	4	27	by	by	ADP
elements-9064	4	28	binding	bind	VERB
elements-9064	4	29	and	and	CCONJ
elements-9064	4	30	degrading	degrade	VERB
elements-9064	4	31	host	host	NOUN
elements-9064	4	32	a3	a3	NOUN
elements-9064	4	33	proteins	protein	NOUN
elements-9064	4	34	.	.	PUNCT
elements-9064	5	1	a3fs	a3fs	NOUN
elements-9064	5	2	of	of	ADP
elements-9064	5	3	several	several	ADJ
elements-9064	5	4	old	old	ADJ
elements-9064	5	5	world	world	NOUN
elements-9064	5	6	primate	primate	NOUN
elements-9064	5	7	species	specie	NOUN
elements-9064	5	8	were	be	AUX
elements-9064	5	9	genotyped	genotype	VERB
elements-9064	5	10	,	,	PUNCT
elements-9064	5	11	and	and	CCONJ
elements-9064	5	12	the	the	DET
elements-9064	5	13	sequences	sequence	NOUN
elements-9064	5	14	revealed	reveal	VERB
elements-9064	5	15	both	both	DET
elements-9064	5	16	intra	intra	ADJ
elements-9064	5	17	-	-	ADJ
elements-9064	5	18	species	species	ADJ
elements-9064	5	19	diversity	diversity	NOUN
elements-9064	5	20	and	and	CCONJ
elements-9064	5	21	inter	inter	ADJ
elements-9064	5	22	-	-	ADJ
elements-9064	5	23	species	species	ADJ
elements-9064	5	24	divergence	divergence	NOUN
elements-9064	5	25	.	.	PUNCT
elements-9064	6	1	representative	representative	ADJ
elements-9064	6	2	rhesus	rhesus	NOUN
elements-9064	6	3	macaque	macaque	NOUN
elements-9064	6	4	(	(	PUNCT
elements-9064	6	5	macaca	macaca	NOUN
elements-9064	6	6	mulatta	mulatta	PROPN
elements-9064	6	7	)	)	PUNCT
elements-9064	6	8	sequences	sequence	NOUN
elements-9064	6	9	were	be	AUX
elements-9064	6	10	cloned	clone	VERB
elements-9064	6	11	and	and	CCONJ
elements-9064	6	12	tested	test	VERB
elements-9064	6	13	for	for	ADP
elements-9064	6	14	sensitivity	sensitivity	NOUN
elements-9064	6	15	to	to	ADP
elements-9064	6	16	vifs	vif	NOUN
elements-9064	6	17	from	from	ADP
elements-9064	6	18	various	various	ADJ
elements-9064	6	19	simian	simian	ADJ
elements-9064	6	20	immunodeficiency	immunodeficiency	NOUN
elements-9064	6	21	viruses	virus	NOUN
elements-9064	6	22	(	(	PUNCT
elements-9064	6	23	sivs	sivs	NOUN
elements-9064	6	24	)	)	PUNCT
elements-9064	6	25	.	.	PUNCT
elements-9064	7	1	evolution	evolution	NOUN
elements-9064	7	2	of	of	ADP
elements-9064	7	3	a3f	a3f	PROPN
elements-9064	7	4	in	in	ADP
elements-9064	7	5	the	the	DET
elements-9064	7	6	rhesus	rhesus	NOUN
elements-9064	7	7	lineage	lineage	NOUN
elements-9064	7	8	is	be	AUX
elements-9064	7	9	not	not	PART
elements-9064	7	10	due	due	ADJ
elements-9064	7	11	to	to	ADP
elements-9064	7	12	selection	selection	NOUN
elements-9064	7	13	by	by	ADP
elements-9064	7	14	sivs	sivs	NOUN
elements-9064	7	15	,	,	PUNCT
elements-9064	7	16	but	but	CCONJ
elements-9064	7	17	may	may	AUX
elements-9064	7	18	reflect	reflect	VERB
elements-9064	7	19	antagonism	antagonism	NOUN
elements-9064	7	20	by	by	ADP
elements-9064	7	21	another	another	DET
elements-9064	7	22	retrovirus	retrovirus	NOUN
elements-9064	7	23	.	.	PUNCT
elements-9064	8	1	a	a	DET
elements-9064	8	2	biological	biological	ADJ
elements-9064	8	3	“	"	PUNCT
elements-9064	8	4	arms	arm	NOUN
elements-9064	8	5	race	race	NOUN
elements-9064	8	6	”	"	PUNCT
elements-9064	8	7	apobec3f	apobec3f	PROPN
elements-9064	8	8	diversity	diversity	NOUN
elements-9064	8	9	and	and	CCONJ
elements-9064	8	10	its	its	PRON
elements-9064	8	11	influence	influence	NOUN
elements-9064	8	12	on	on	ADP
elements-9064	8	13	lentiviral	lentiviral	ADJ
elements-9064	8	14	resistance	resistance	NOUN
elements-9064	8	15	allyson	allyson	PROPN
elements-9064	8	16	tank	tank	PROPN
elements-9064	8	17	introduction	introduction	NOUN
elements-9064	8	18	i.	i.	NOUN
elements-9064	8	19	restriction	restriction	NOUN
elements-9064	8	20	factors	factor	NOUN
elements-9064	8	21	:	:	PUNCT
elements-9064	8	22	barriers	barrier	NOUN
elements-9064	8	23	to	to	PART
elements-9064	8	24	cross	cross	VERB
elements-9064	8	25	species	species	NOUN
elements-9064	8	26	transmission	transmission	NOUN
elements-9064	8	27	acquired	acquire	VERB
elements-9064	8	28	immune	immune	ADJ
elements-9064	8	29	deficiency	deficiency	NOUN
elements-9064	8	30	syndrome	syndrome	NOUN
elements-9064	8	31	(	(	PUNCT
elements-9064	8	32	aids	aids	PROPN
elements-9064	8	33	)	)	PUNCT
elements-9064	8	34	was	be	AUX
elements-9064	8	35	first	first	ADV
elements-9064	8	36	identified	identify	VERB
elements-9064	8	37	as	as	ADP
elements-9064	8	38	a	a	DET
elements-9064	8	39	disease	disease	NOUN
elements-9064	8	40	in	in	ADP
elements-9064	8	41	1981	1981	NUM
elements-9064	8	42	,	,	PUNCT
elements-9064	8	43	as	as	SCONJ
elements-9064	8	44	increasing	increase	VERB
elements-9064	8	45	numbers	number	NOUN
elements-9064	8	46	of	of	ADP
elements-9064	8	47	homosexual	homosexual	ADJ
elements-9064	8	48	men	man	NOUN
elements-9064	8	49	were	be	AUX
elements-9064	8	50	dying	die	VERB
elements-9064	8	51	of	of	ADP
elements-9064	8	52	opportunistic	opportunistic	ADJ
elements-9064	8	53	infections	infection	NOUN
elements-9064	8	54	after	after	ADP
elements-9064	8	55	becoming	become	VERB
elements-9064	8	56	immunocompromised.1	immunocompromised.1	NOUN
elements-9064	8	57	the	the	DET
elements-9064	8	58	causative	causative	ADJ
elements-9064	8	59	agent	agent	NOUN
elements-9064	8	60	was	be	AUX
elements-9064	8	61	soon	soon	ADV
elements-9064	8	62	discovered	discover	VERB
elements-9064	8	63	to	to	PART
elements-9064	8	64	be	be	AUX
elements-9064	8	65	a	a	DET
elements-9064	8	66	lentivirus	lentivirus	NOUN
elements-9064	8	67	,	,	PUNCT
elements-9064	8	68	classified	classify	VERB
elements-9064	8	69	as	as	ADP
elements-9064	8	70	human	human	ADJ
elements-9064	8	71	immunodeficiency	immunodeficiency	NOUN
elements-9064	8	72	virus	virus	NOUN
elements-9064	8	73	type	type	NOUN
elements-9064	8	74	1	1	NUM
elements-9064	8	75	(	(	PUNCT
elements-9064	8	76	hiv-1).2,3	hiv-1).2,3	NOUN
elements-9064	8	77	hiv-1	hiv-1	X
elements-9064	8	78	and	and	CCONJ
elements-9064	8	79	its	its	PRON
elements-9064	8	80	close	close	ADJ
elements-9064	8	81	relative	relative	ADJ
elements-9064	8	82	hiv	hiv	PROPN
elements-9064	8	83	type	type	NOUN
elements-9064	8	84	2	2	NUM
elements-9064	8	85	(	(	PUNCT
elements-9064	8	86	hiv-2	hiv-2	ADV
elements-9064	8	87	)	)	PUNCT
elements-9064	8	88	arose	arise	VERB
elements-9064	8	89	in	in	ADP
elements-9064	8	90	human	human	ADJ
elements-9064	8	91	populations	population	NOUN
elements-9064	8	92	as	as	ADP
elements-9064	8	93	a	a	DET
elements-9064	8	94	result	result	NOUN
elements-9064	8	95	of	of	ADP
elements-9064	8	96	cross	cross	ADJ
elements-9064	8	97	-	-	ADJ
elements-9064	8	98	species	species	ADJ
elements-9064	8	99	transmission	transmission	NOUN
elements-9064	8	100	events	event	NOUN
elements-9064	8	101	from	from	ADP
elements-9064	8	102	natural	natural	ADJ
elements-9064	8	103	simian	simian	ADJ
elements-9064	8	104	hosts	host	NOUN
elements-9064	8	105	of	of	ADP
elements-9064	8	106	the	the	DET
elements-9064	8	107	simian	simian	ADJ
elements-9064	8	108	immunodeficiency	immunodeficiency	NOUN
elements-9064	8	109	viruses	virus	NOUN
elements-9064	8	110	(	(	PUNCT
elements-9064	8	111	sivs	sivs	NOUN
elements-9064	8	112	)	)	PUNCT
elements-9064	8	113	.	.	PUNCT
elements-9064	9	1	the	the	DET
elements-9064	9	2	closest	close	ADJ
elements-9064	9	3	simian	simian	ADJ
elements-9064	9	4	relative	relative	NOUN
elements-9064	9	5	of	of	ADP
elements-9064	9	6	hiv-1	hiv-1	PUNCT
elements-9064	9	7	is	be	AUX
elements-9064	9	8	the	the	DET
elements-9064	9	9	strain	strain	NOUN
elements-9064	9	10	naturally	naturally	ADV
elements-9064	9	11	infecting	infect	VERB
elements-9064	9	12	chimpanzees	chimpanzee	NOUN
elements-9064	9	13	(	(	PUNCT
elements-9064	9	14	sivcpz),4	sivcpz),4	X
elements-9064	9	15	while	while	SCONJ
elements-9064	9	16	the	the	DET
elements-9064	9	17	closest	close	ADJ
elements-9064	9	18	simian	simian	ADJ
elements-9064	9	19	relative	relative	NOUN
elements-9064	9	20	of	of	ADP
elements-9064	9	21	hiv-2	hiv-2	PUNCT
elements-9064	9	22	is	be	AUX
elements-9064	9	23	the	the	DET
elements-9064	9	24	strain	strain	NOUN
elements-9064	9	25	naturally	naturally	ADV
elements-9064	9	26	infecting	infect	VERB
elements-9064	9	27	sooty	sooty	NOUN
elements-9064	9	28	mangabeys	mangabey	NOUN
elements-9064	9	29	(	(	PUNCT
elements-9064	9	30	sivsm).5	sivsm).5	VERB
elements-9064	9	31	over	over	ADP
elements-9064	9	32	40	40	NUM
elements-9064	9	33	species	specie	NOUN
elements-9064	9	34	-	-	PUNCT
elements-9064	9	35	specific	specific	ADJ
elements-9064	9	36	sivs	sivs	NOUN
elements-9064	9	37	have	have	AUX
elements-9064	9	38	since	since	SCONJ
elements-9064	9	39	been	be	AUX
elements-9064	9	40	identified	identify	VERB
elements-9064	9	41	in	in	ADP
elements-9064	9	42	nonhuman	nonhuman	ADJ
elements-9064	9	43	primate	primate	NOUN
elements-9064	9	44	species	specie	NOUN
elements-9064	9	45	.	.	PUNCT
elements-9064	10	1	a	a	DET
elements-9064	10	2	fraction	fraction	NOUN
elements-9064	10	3	of	of	ADP
elements-9064	10	4	these	these	DET
elements-9064	10	5	infections	infection	NOUN
elements-9064	10	6	result	result	VERB
elements-9064	10	7	in	in	ADP
elements-9064	10	8	immunodeficiency	immunodeficiency	NOUN
elements-9064	10	9	in	in	ADP
elements-9064	10	10	the	the	DET
elements-9064	10	11	host	host	NOUN
elements-9064	10	12	species	specie	NOUN
elements-9064	10	13	,	,	PUNCT
elements-9064	10	14	while	while	SCONJ
elements-9064	10	15	most	most	ADJ
elements-9064	10	16	are	be	AUX
elements-9064	10	17	nonpathogenic	nonpathogenic	ADJ
elements-9064	10	18	in	in	ADP
elements-9064	10	19	their	their	PRON
elements-9064	10	20	natural	natural	ADJ
elements-9064	10	21	hosts.6	hosts.6	PROPN
elements-9064	10	22	the	the	DET
elements-9064	10	23	siv	siv	PROPN
elements-9064	10	24	of	of	ADP
elements-9064	10	25	a	a	DET
elements-9064	10	26	given	give	VERB
elements-9064	10	27	primate	primate	NOUN
elements-9064	10	28	species	specie	NOUN
elements-9064	10	29	can	can	AUX
elements-9064	10	30	not	not	PART
elements-9064	10	31	readily	readily	ADV
elements-9064	10	32	infect	infect	VERB
elements-9064	10	33	a	a	DET
elements-9064	10	34	different	different	ADJ
elements-9064	10	35	species	specie	NOUN
elements-9064	10	36	without	without	ADP
elements-9064	10	37	undergoing	undergo	VERB
elements-9064	10	38	numerous	numerous	ADJ
elements-9064	10	39	adaptations	adaptation	NOUN
elements-9064	10	40	.	.	PUNCT
elements-9064	11	1	part	part	NOUN
elements-9064	11	2	of	of	ADP
elements-9064	11	3	this	this	DET
elements-9064	11	4	adaptation	adaptation	NOUN
elements-9064	11	5	process	process	NOUN
elements-9064	11	6	involves	involve	VERB
elements-9064	11	7	evading	evade	VERB
elements-9064	11	8	host	host	NOUN
elements-9064	11	9	antiviral	antiviral	ADJ
elements-9064	11	10	proteins	protein	NOUN
elements-9064	11	11	known	know	VERB
elements-9064	11	12	as	as	ADP
elements-9064	11	13	restriction	restriction	NOUN
elements-9064	11	14	factors	factor	NOUN
elements-9064	11	15	.	.	PUNCT
elements-9064	12	1	restriction	restriction	NOUN
elements-9064	12	2	factors	factor	NOUN
elements-9064	12	3	are	be	AUX
elements-9064	12	4	host	host	NOUN
elements-9064	12	5	proteins	protein	NOUN
elements-9064	12	6	that	that	PRON
elements-9064	12	7	utilize	utilize	VERB
elements-9064	12	8	numerous	numerous	ADJ
elements-9064	12	9	mechanisms	mechanism	NOUN
elements-9064	12	10	to	to	PART
elements-9064	12	11	interfere	interfere	VERB
elements-9064	12	12	with	with	ADP
elements-9064	12	13	viral	viral	ADJ
elements-9064	12	14	infections	infection	NOUN
elements-9064	12	15	as	as	ADP
elements-9064	12	16	part	part	NOUN
elements-9064	12	17	of	of	ADP
elements-9064	12	18	the	the	DET
elements-9064	12	19	innate	innate	ADJ
elements-9064	12	20	immune	immune	ADJ
elements-9064	12	21	response	response	NOUN
elements-9064	12	22	.	.	PUNCT
elements-9064	13	1	some	some	DET
elements-9064	13	2	interact	interact	VERB
elements-9064	13	3	directly	directly	ADV
elements-9064	13	4	with	with	ADP
elements-9064	13	5	viral	viral	ADJ
elements-9064	13	6	factors	factor	NOUN
elements-9064	13	7	,	,	PUNCT
elements-9064	13	8	while	while	SCONJ
elements-9064	13	9	others	other	NOUN
elements-9064	13	10	make	make	VERB
elements-9064	13	11	the	the	DET
elements-9064	13	12	cellular	cellular	ADJ
elements-9064	13	13	environment	environment	NOUN
elements-9064	13	14	unsuitable	unsuitable	ADJ
elements-9064	13	15	for	for	ADP
elements-9064	13	16	sustained	sustain	VERB
elements-9064	13	17	viral	viral	ADJ
elements-9064	13	18	replication.7	replication.7	NOUN
elements-9064	13	19	these	these	DET
elements-9064	13	20	defensive	defensive	ADJ
elements-9064	13	21	genes	gene	NOUN
elements-9064	13	22	are	be	AUX
elements-9064	13	23	subject	subject	ADJ
elements-9064	13	24	to	to	ADP
elements-9064	13	25	relatively	relatively	ADV
elements-9064	13	26	rapid	rapid	ADJ
elements-9064	13	27	evolution	evolution	NOUN
elements-9064	13	28	under	under	ADP
elements-9064	13	29	the	the	DET
elements-9064	13	30	selective	selective	ADJ
elements-9064	13	31	pressure	pressure	NOUN
elements-9064	13	32	of	of	ADP
elements-9064	13	33	viral	viral	ADJ
elements-9064	13	34	counter	counter	ADJ
elements-9064	13	35	-	-	NOUN
elements-9064	13	36	restriction	restriction	NOUN
elements-9064	13	37	mechanisms	mechanism	NOUN
elements-9064	13	38	,	,	PUNCT
elements-9064	13	39	and	and	CCONJ
elements-9064	13	40	variants	variant	NOUN
elements-9064	13	41	that	that	PRON
elements-9064	13	42	confer	confer	VERB
elements-9064	13	43	greater	great	ADJ
elements-9064	13	44	fitness	fitness	NOUN
elements-9064	13	45	to	to	ADP
elements-9064	13	46	the	the	DET
elements-9064	13	47	host	host	NOUN
elements-9064	13	48	during	during	ADP
elements-9064	13	49	a	a	DET
elements-9064	13	50	viral	viral	ADJ
elements-9064	13	51	outbreak	outbreak	NOUN
elements-9064	13	52	will	will	AUX
elements-9064	13	53	become	become	AUX
elements-9064	13	54	fixed	fix	VERB
elements-9064	13	55	in	in	ADP
elements-9064	13	56	a	a	DET
elements-9064	13	57	population	population	NOUN
elements-9064	13	58	much	much	ADV
elements-9064	13	59	faster	fast	ADV
elements-9064	13	60	than	than	SCONJ
elements-9064	13	61	would	would	AUX
elements-9064	13	62	normally	normally	ADV
elements-9064	13	63	be	be	AUX
elements-9064	13	64	expected	expect	VERB
elements-9064	13	65	as	as	ADP
elements-9064	13	66	a	a	DET
elements-9064	13	67	result	result	NOUN
elements-9064	13	68	of	of	ADP
elements-9064	13	69	genetic	genetic	ADJ
elements-9064	13	70	drift	drift	NOUN
elements-9064	13	71	alone	alone	ADV
elements-9064	13	72	.	.	PUNCT
elements-9064	14	1	the	the	DET
elements-9064	14	2	virus	virus	NOUN
elements-9064	14	3	,	,	PUNCT
elements-9064	14	4	in	in	ADP
elements-9064	14	5	turn	turn	NOUN
elements-9064	14	6	,	,	PUNCT
elements-9064	14	7	can	can	AUX
elements-9064	14	8	adapt	adapt	VERB
elements-9064	14	9	to	to	PART
elements-9064	14	10	infect	infect	VERB
elements-9064	14	11	the	the	DET
elements-9064	14	12	host	host	NOUN
elements-9064	14	13	carrying	carry	VERB
elements-9064	14	14	these	these	DET
elements-9064	14	15	more	more	ADV
elements-9064	14	16	fit	fit	ADJ
elements-9064	14	17	alleles	allele	NOUN
elements-9064	14	18	,	,	PUNCT
elements-9064	14	19	creating	create	VERB
elements-9064	14	20	a	a	DET
elements-9064	14	21	new	new	ADJ
elements-9064	14	22	selective	selective	ADJ
elements-9064	14	23	pressure	pressure	NOUN
elements-9064	14	24	on	on	ADP
elements-9064	14	25	the	the	DET
elements-9064	14	26	host	host	NOUN
elements-9064	14	27	.	.	PUNCT
elements-9064	15	1	thus	thus	ADV
elements-9064	15	2	,	,	PUNCT
elements-9064	15	3	over	over	ADP
elements-9064	15	4	evolutionary	evolutionary	ADJ
elements-9064	15	5	time	time	NOUN
elements-9064	15	6	,	,	PUNCT
elements-9064	15	7	a	a	DET
elements-9064	15	8	comparatively	comparatively	ADV
elements-9064	15	9	large	large	ADJ
elements-9064	15	10	number	number	NOUN
elements-9064	15	11	of	of	ADP
elements-9064	15	12	non	non	ADJ
elements-9064	15	13	-	-	ADJ
elements-9064	15	14	synonymous	synonymous	ADJ
elements-9064	15	15	,	,	PUNCT
elements-9064	15	16	or	or	CCONJ
elements-9064	15	17	protein	protein	NOUN
elements-9064	15	18	-	-	PUNCT
elements-9064	15	19	altering	alter	VERB
elements-9064	15	20	,	,	PUNCT
elements-9064	15	21	mutations	mutation	NOUN
elements-9064	15	22	will	will	AUX
elements-9064	15	23	be	be	AUX
elements-9064	15	24	evident	evident	ADJ
elements-9064	15	25	in	in	ADP
elements-9064	15	26	genes	gene	NOUN
elements-9064	15	27	that	that	PRON
elements-9064	15	28	have	have	AUX
elements-9064	15	29	participated	participate	VERB
elements-9064	15	30	in	in	ADP
elements-9064	15	31	these	these	DET
elements-9064	15	32	virus	virus	NOUN
elements-9064	15	33	-	-	PUNCT
elements-9064	15	34	host	host	NOUN
elements-9064	15	35	“	"	PUNCT
elements-9064	15	36	arms	arm	NOUN
elements-9064	15	37	races	race	NOUN
elements-9064	15	38	.	.	PUNCT
elements-9064	16	1	”8	”8	PUNCT
elements-9064	16	2	genes	gene	NOUN
elements-9064	16	3	can	can	AUX
elements-9064	16	4	be	be	AUX
elements-9064	16	5	examined	examine	VERB
elements-9064	16	6	for	for	ADP
elements-9064	16	7	evidence	evidence	NOUN
elements-9064	16	8	of	of	ADP
elements-9064	16	9	positive	positive	ADJ
elements-9064	16	10	selection	selection	NOUN
elements-9064	16	11	by	by	ADP
elements-9064	16	12	comparing	compare	VERB
elements-9064	16	13	the	the	DET
elements-9064	16	14	rate	rate	NOUN
elements-9064	16	15	of	of	ADP
elements-9064	16	16	fixation	fixation	NOUN
elements-9064	16	17	of	of	ADP
elements-9064	16	18	non	non	ADJ
elements-9064	16	19	-	-	ADJ
elements-9064	16	20	synonymous	synonymous	ADJ
elements-9064	16	21	mutations	mutation	NOUN
elements-9064	16	22	(	(	PUNCT
elements-9064	16	23	n	n	CCONJ
elements-9064	16	24	)	)	PUNCT
elements-9064	16	25	to	to	ADP
elements-9064	16	26	the	the	DET
elements-9064	16	27	rate	rate	NOUN
elements-9064	16	28	of	of	ADP
elements-9064	16	29	fixation	fixation	NOUN
elements-9064	16	30	of	of	ADP
elements-9064	16	31	synonymous	synonymous	ADJ
elements-9064	16	32	mutations	mutation	NOUN
elements-9064	16	33	(	(	PUNCT
elements-9064	16	34	s	s	NOUN
elements-9064	16	35	)	)	PUNCT
elements-9064	16	36	.	.	PUNCT
elements-9064	17	1	dn	dn	ADJ
elements-9064	17	2	/	/	SYM
elements-9064	17	3	ds	ds	ADJ
elements-9064	17	4	analysis	analysis	NOUN
elements-9064	17	5	demonstrates	demonstrate	VERB
elements-9064	17	6	whether	whether	SCONJ
elements-9064	17	7	fixation	fixation	NOUN
elements-9064	17	8	of	of	ADP
elements-9064	17	9	nonsynonymous	nonsynonymous	ADJ
elements-9064	17	10	changes	change	NOUN
elements-9064	17	11	is	be	AUX
elements-9064	17	12	occurring	occur	VERB
elements-9064	17	13	faster	fast	ADV
elements-9064	17	14	than	than	SCONJ
elements-9064	17	15	expected	expect	VERB
elements-9064	17	16	under	under	ADP
elements-9064	17	17	neutral	neutral	ADJ
elements-9064	17	18	selection	selection	NOUN
elements-9064	17	19	alone	alone	ADV
elements-9064	17	20	.	.	PUNCT
elements-9064	18	1	a	a	DET
elements-9064	18	2	dn	dn	ADJ
elements-9064	18	3	/	/	SYM
elements-9064	18	4	ds	ds	ADJ
elements-9064	18	5	value	value	NOUN
elements-9064	18	6	greater	great	ADJ
elements-9064	18	7	than	than	ADP
elements-9064	18	8	one	one	NUM
elements-9064	18	9	indicates	indicate	VERB
elements-9064	18	10	that	that	SCONJ
elements-9064	18	11	a	a	DET
elements-9064	18	12	particular	particular	ADJ
elements-9064	18	13	site	site	NOUN
elements-9064	18	14	is	be	AUX
elements-9064	18	15	evolving	evolve	VERB
elements-9064	18	16	under	under	ADP
elements-9064	18	17	positive	positive	ADJ
elements-9064	18	18	selection	selection	NOUN
elements-9064	18	19	,	,	PUNCT
elements-9064	18	20	while	while	SCONJ
elements-9064	18	21	a	a	DET
elements-9064	18	22	dn	dn	ADJ
elements-9064	18	23	/	/	SYM
elements-9064	18	24	ds	ds	ADJ
elements-9064	18	25	value	value	NOUN
elements-9064	18	26	less	less	ADJ
elements-9064	18	27	than	than	ADP
elements-9064	18	28	one	one	NUM
elements-9064	18	29	indicates	indicate	VERB
elements-9064	18	30	that	that	SCONJ
elements-9064	18	31	a	a	DET
elements-9064	18	32	site	site	NOUN
elements-9064	18	33	is	be	AUX
elements-9064	18	34	evolving	evolve	VERB
elements-9064	18	35	under	under	ADP
elements-9064	18	36	purifying	purify	VERB
elements-9064	18	37	selection.9	selection.9	NOUN
elements-9064	18	38	this	this	DET
elements-9064	18	39	idea	idea	NOUN
elements-9064	18	40	of	of	ADP
elements-9064	18	41	a	a	DET
elements-9064	18	42	virus	virus	NOUN
elements-9064	18	43	-	-	PUNCT
elements-9064	18	44	host	host	NOUN
elements-9064	18	45	“	"	PUNCT
elements-9064	18	46	arms	arm	NOUN
elements-9064	18	47	race	race	NOUN
elements-9064	18	48	”	"	PUNCT
elements-9064	18	49	is	be	AUX
elements-9064	18	50	a	a	DET
elements-9064	18	51	fairly	fairly	ADV
elements-9064	18	52	simplified	simplified	ADJ
elements-9064	18	53	model	model	NOUN
elements-9064	18	54	.	.	PUNCT
elements-9064	19	1	rna	rna	NOUN
elements-9064	19	2	viruses	virus	NOUN
elements-9064	19	3	can	can	AUX
elements-9064	19	4	diversify	diversify	VERB
elements-9064	19	5	their	their	PRON
elements-9064	19	6	genome	genome	NOUN
elements-9064	19	7	at	at	ADP
elements-9064	19	8	a	a	DET
elements-9064	19	9	much	much	ADV
elements-9064	19	10	higher	high	ADJ
elements-9064	19	11	rate	rate	NOUN
elements-9064	19	12	than	than	SCONJ
elements-9064	19	13	their	their	PRON
elements-9064	19	14	hosts	host	NOUN
elements-9064	19	15	can	can	AUX
elements-9064	19	16	.	.	PUNCT
elements-9064	20	1	hosts	host	NOUN
elements-9064	20	2	keep	keep	VERB
elements-9064	20	3	up	up	ADP
elements-9064	20	4	through	through	ADP
elements-9064	20	5	diversity	diversity	NOUN
elements-9064	20	6	of	of	ADP
elements-9064	20	7	antiviral	antiviral	ADJ
elements-9064	20	8	mechanisms	mechanism	NOUN
elements-9064	20	9	rather	rather	ADV
elements-9064	20	10	than	than	ADP
elements-9064	20	11	rapid	rapid	ADJ
elements-9064	20	12	counterrevolution	counterrevolution	NOUN
elements-9064	20	13	.	.	PUNCT
elements-9064	21	1	a	a	DET
elements-9064	21	2	viral	viral	ADJ
elements-9064	21	3	variant	variant	NOUN
elements-9064	21	4	that	that	PRON
elements-9064	21	5	efficiently	efficiently	ADV
elements-9064	21	6	evades	evade	VERB
elements-9064	21	7	one	one	NUM
elements-9064	21	8	host	host	NOUN
elements-9064	21	9	restriction	restriction	NOUN
elements-9064	21	10	mechanism	mechanism	NOUN
elements-9064	21	11	will	will	AUX
elements-9064	21	12	likely	likely	ADV
elements-9064	21	13	become	become	VERB
elements-9064	21	14	more	more	ADV
elements-9064	21	15	susceptible	susceptible	ADJ
elements-9064	21	16	to	to	ADP
elements-9064	21	17	another.10	another.10	ADP
elements-9064	21	18	however	however	ADV
elements-9064	21	19	,	,	PUNCT
elements-9064	21	20	over	over	ADP
elements-9064	21	21	evolutionary	evolutionary	ADJ
elements-9064	21	22	time	time	NOUN
elements-9064	21	23	and	and	CCONJ
elements-9064	21	24	as	as	ADP
elements-9064	21	25	a	a	DET
elements-9064	21	26	result	result	NOUN
elements-9064	21	27	of	of	ADP
elements-9064	21	28	many	many	ADJ
elements-9064	21	29	interactions	interaction	NOUN
elements-9064	21	30	with	with	ADP
elements-9064	21	31	diverse	diverse	ADJ
elements-9064	21	32	viruses	virus	NOUN
elements-9064	21	33	,	,	PUNCT
elements-9064	21	34	host	host	NOUN
elements-9064	21	35	restriction	restriction	NOUN
elements-9064	21	36	factors	factor	NOUN
elements-9064	21	37	bear	bear	VERB
elements-9064	21	38	signatures	signature	NOUN
elements-9064	21	39	of	of	ADP
elements-9064	21	40	positive	positive	ADJ
elements-9064	21	41	selection	selection	NOUN
elements-9064	21	42	.	.	PUNCT
elements-9064	22	1	another	another	DET
elements-9064	22	2	defining	define	VERB
elements-9064	22	3	factor	factor	NOUN
elements-9064	22	4	of	of	ADP
elements-9064	22	5	restriction	restriction	NOUN
elements-9064	22	6	factors	factor	NOUN
elements-9064	22	7	is	be	AUX
elements-9064	22	8	their	their	PRON
elements-9064	22	9	relationships	relationship	NOUN
elements-9064	22	10	with	with	ADP
elements-9064	22	11	viral	viral	ADJ
elements-9064	22	12	antagonist	antagonist	NOUN
elements-9064	22	13	proteins	protein	NOUN
elements-9064	22	14	.	.	PUNCT
elements-9064	23	1	in	in	ADP
elements-9064	23	2	many	many	ADJ
elements-9064	23	3	cases	case	NOUN
elements-9064	23	4	,	,	PUNCT
elements-9064	23	5	viruses	virus	NOUN
elements-9064	23	6	have	have	AUX
elements-9064	23	7	evolved	evolve	VERB
elements-9064	23	8	specific	specific	ADJ
elements-9064	23	9	proteins	protein	NOUN
elements-9064	23	10	to	to	PART
elements-9064	23	11	evade	evade	VERB
elements-9064	23	12	the	the	DET
elements-9064	23	13	mechanism	mechanism	NOUN
elements-9064	23	14	of	of	ADP
elements-9064	23	15	a	a	DET
elements-9064	23	16	particular	particular	ADJ
elements-9064	23	17	restriction	restriction	NOUN
elements-9064	23	18	factor	factor	NOUN
elements-9064	23	19	.	.	PUNCT
elements-9064	24	1	this	this	DET
elements-9064	24	2	virus	virus	NOUN
elements-9064	24	3	-	-	PUNCT
elements-9064	24	4	host	host	NOUN
elements-9064	24	5	relationship	relationship	NOUN
elements-9064	24	6	is	be	AUX
elements-9064	24	7	highly	highly	ADV
elements-9064	24	8	species	specie	NOUN
elements-9064	24	9	-	-	PUNCT
elements-9064	24	10	specific	specific	ADJ
elements-9064	24	11	because	because	SCONJ
elements-9064	24	12	of	of	ADP
elements-9064	24	13	the	the	DET
elements-9064	24	14	rapid	rapid	ADJ
elements-9064	24	15	adaptation	adaptation	NOUN
elements-9064	24	16	process	process	NOUN
elements-9064	24	17	.	.	PUNCT
elements-9064	25	1	as	as	ADP
elements-9064	25	2	a	a	DET
elements-9064	25	3	general	general	ADJ
elements-9064	25	4	rule	rule	NOUN
elements-9064	25	5	,	,	PUNCT
elements-9064	25	6	any	any	DET
elements-9064	25	7	given	give	VERB
elements-9064	25	8	virus	virus	NOUN
elements-9064	25	9	will	will	AUX
elements-9064	25	10	have	have	VERB
elements-9064	25	11	accessory	accessory	ADJ
elements-9064	25	12	proteins	protein	NOUN
elements-9064	25	13	that	that	PRON
elements-9064	25	14	are	be	AUX
elements-9064	25	15	most	most	ADV
elements-9064	25	16	effective	effective	ADJ
elements-9064	25	17	at	at	ADP
elements-9064	25	18	neutralizing	neutralize	VERB
elements-9064	25	19	the	the	DET
elements-9064	25	20	restriction	restriction	NOUN
elements-9064	25	21	mechanisms	mechanism	NOUN
elements-9064	25	22	of	of	ADP
elements-9064	25	23	its	its	PRON
elements-9064	25	24	natural	natural	ADJ
elements-9064	25	25	host	host	NOUN
elements-9064	25	26	,	,	PUNCT
elements-9064	25	27	but	but	CCONJ
elements-9064	25	28	may	may	AUX
elements-9064	25	29	not	not	PART
elements-9064	25	30	be	be	AUX
elements-9064	25	31	effective	effective	ADJ
elements-9064	25	32	against	against	ADP
elements-9064	25	33	the	the	DET
elements-9064	25	34	homologous	homologous	ADJ
elements-9064	25	35	restriction	restriction	NOUN
elements-9064	25	36	mechanisms	mechanism	NOUN
elements-9064	25	37	of	of	ADP
elements-9064	25	38	other	other	ADJ
elements-9064	25	39	organisms.11	organisms.11	NOUN
elements-9064	25	40	a	a	DET
elements-9064	25	41	variety	variety	NOUN
elements-9064	25	42	of	of	ADP
elements-9064	25	43	restriction	restriction	NOUN
elements-9064	25	44	factors	factor	NOUN
elements-9064	25	45	have	have	AUX
elements-9064	25	46	been	be	AUX
elements-9064	25	47	implicated	implicate	VERB
elements-9064	25	48	in	in	ADP
elements-9064	25	49	differential	differential	ADJ
elements-9064	25	50	host	host	NOUN
elements-9064	25	51	resistance	resistance	NOUN
elements-9064	25	52	to	to	PART
elements-9064	25	53	primate	primate	VERB
elements-9064	25	54	lentiviruses	lentiviruse	NOUN
elements-9064	25	55	,	,	PUNCT
elements-9064	25	56	like	like	ADP
elements-9064	25	57	hiv	hiv	PROPN
elements-9064	25	58	and	and	CCONJ
elements-9064	25	59	the	the	DET
elements-9064	25	60	sivs	sivs	NOUN
elements-9064	25	61	.	.	PUNCT
elements-9064	26	1	lentiviruses	lentiviruse	NOUN
elements-9064	26	2	are	be	AUX
elements-9064	26	3	part	part	NOUN
elements-9064	26	4	of	of	ADP
elements-9064	26	5	the	the	DET
elements-9064	26	6	retrovirus	retrovirus	NOUN
elements-9064	26	7	family	family	NOUN
elements-9064	26	8	,	,	PUNCT
elements-9064	26	9	and	and	CCONJ
elements-9064	26	10	their	their	PRON
elements-9064	26	11	life	life	NOUN
elements-9064	26	12	cycle	cycle	NOUN
elements-9064	26	13	is	be	AUX
elements-9064	26	14	well	well	ADV
elements-9064	26	15	understood	understand	VERB
elements-9064	26	16	.	.	PUNCT
elements-9064	27	1	in	in	ADP
elements-9064	27	2	order	order	NOUN
elements-9064	27	3	to	to	PART
elements-9064	27	4	infect	infect	VERB
elements-9064	27	5	a	a	DET
elements-9064	27	6	new	new	ADJ
elements-9064	27	7	target	target	NOUN
elements-9064	27	8	cell	cell	NOUN
elements-9064	27	9	,	,	PUNCT
elements-9064	27	10	the	the	DET
elements-9064	27	11	virion	virion	NOUN
elements-9064	27	12	will	will	AUX
elements-9064	27	13	first	first	ADV
elements-9064	27	14	bind	bind	VERB
elements-9064	27	15	to	to	ADP
elements-9064	27	16	a	a	DET
elements-9064	27	17	cd4	cd4	PROPN
elements-9064	27	18	receptor	receptor	NOUN
elements-9064	27	19	and	and	CCONJ
elements-9064	27	20	co	co	NOUN
elements-9064	27	21	-	-	NOUN
elements-9064	27	22	receptors	receptor	NOUN
elements-9064	27	23	on	on	ADP
elements-9064	27	24	the	the	DET
elements-9064	27	25	cell	cell	NOUN
elements-9064	27	26	surface	surface	NOUN
elements-9064	27	27	.	.	PUNCT
elements-9064	28	1	the	the	DET
elements-9064	28	2	virion	virion	NOUN
elements-9064	28	3	membrane	membrane	NOUN
elements-9064	28	4	fuses	fuse	NOUN
elements-9064	28	5	with	with	ADP
elements-9064	28	6	the	the	DET
elements-9064	28	7	cell	cell	NOUN
elements-9064	28	8	membrane	membrane	NOUN
elements-9064	28	9	and	and	CCONJ
elements-9064	28	10	the	the	DET
elements-9064	28	11	capsid	capsid	NOUN
elements-9064	28	12	is	be	AUX
elements-9064	28	13	released	release	VERB
elements-9064	28	14	into	into	ADP
elements-9064	28	15	the	the	DET
elements-9064	28	16	cytoplasm	cytoplasm	NOUN
elements-9064	28	17	.	.	PUNCT
elements-9064	29	1	the	the	DET
elements-9064	29	2	viral	viral	ADJ
elements-9064	29	3	rna	rna	NOUN
elements-9064	29	4	within	within	ADP
elements-9064	29	5	the	the	DET
elements-9064	29	6	capsid	capsid	NOUN
elements-9064	29	7	then	then	ADV
elements-9064	29	8	undergoes	undergo	VERB
elements-9064	29	9	reverse	reverse	ADJ
elements-9064	29	10	transcription	transcription	NOUN
elements-9064	29	11	in	in	ADP
elements-9064	29	12	the	the	DET
elements-9064	29	13	cytoplasm	cytoplasm	NOUN
elements-9064	29	14	to	to	PART
elements-9064	29	15	form	form	VERB
elements-9064	29	16	dna	dna	NOUN
elements-9064	29	17	that	that	PRON
elements-9064	29	18	is	be	AUX
elements-9064	29	19	transported	transport	VERB
elements-9064	29	20	into	into	ADP
elements-9064	29	21	the	the	DET
elements-9064	29	22	nucleus	nucleus	NOUN
elements-9064	29	23	and	and	CCONJ
elements-9064	29	24	integrated	integrate	VERB
elements-9064	29	25	into	into	ADP
elements-9064	29	26	the	the	DET
elements-9064	29	27	host	host	NOUN
elements-9064	29	28	genome	genome	NOUN
elements-9064	29	29	.	.	PUNCT
elements-9064	30	1	the	the	DET
elements-9064	30	2	viral	viral	ADJ
elements-9064	30	3	dna	dna	NOUN
elements-9064	30	4	is	be	AUX
elements-9064	30	5	transcribed	transcribe	VERB
elements-9064	30	6	and	and	CCONJ
elements-9064	30	7	translated	translate	VERB
elements-9064	30	8	using	use	VERB
elements-9064	30	9	host	host	NOUN
elements-9064	30	10	machinery	machinery	NOUN
elements-9064	30	11	,	,	PUNCT
elements-9064	30	12	and	and	CCONJ
elements-9064	30	13	then	then	ADV
elements-9064	30	14	viral	viral	ADJ
elements-9064	30	15	rna	rna	NOUN
elements-9064	30	16	and	and	CCONJ
elements-9064	30	17	proteins	protein	NOUN
elements-9064	30	18	are	be	AUX
elements-9064	30	19	localized	localize	VERB
elements-9064	30	20	to	to	ADP
elements-9064	30	21	the	the	DET
elements-9064	30	22	cell	cell	NOUN
elements-9064	30	23	membrane	membrane	NOUN
elements-9064	30	24	to	to	PART
elements-9064	30	25	form	form	VERB
elements-9064	30	26	new	new	ADJ
elements-9064	30	27	virions	virion	NOUN
elements-9064	30	28	.	.	PUNCT
elements-9064	31	1	the	the	DET
elements-9064	31	2	restriction	restriction	NOUN
elements-9064	31	3	factors	factor	NOUN
elements-9064	31	4	of	of	ADP
elements-9064	31	5	primate	primate	ADJ
elements-9064	31	6	lentiviruses	lentiviruse	NOUN
elements-9064	31	7	have	have	AUX
elements-9064	31	8	evolved	evolve	VERB
elements-9064	31	9	to	to	PART
elements-9064	31	10	interfere	interfere	VERB
elements-9064	31	11	with	with	ADP
elements-9064	31	12	nearly	nearly	ADV
elements-9064	31	13	every	every	PRON
elements-9064	31	14	aspect	aspect	NOUN
elements-9064	31	15	of	of	ADP
elements-9064	31	16	this	this	DET
elements-9064	31	17	life	life	NOUN
elements-9064	31	18	cycle	cycle	NOUN
elements-9064	31	19	,	,	PUNCT
elements-9064	31	20	and	and	CCONJ
elements-9064	31	21	thus	thus	ADV
elements-9064	31	22	act	act	VERB
elements-9064	31	23	as	as	ADP
elements-9064	31	24	barriers	barrier	NOUN
elements-9064	31	25	to	to	ADP
elements-9064	31	26	cross	cross	ADJ
elements-9064	31	27	-	-	ADJ
elements-9064	31	28	species	species	ADJ
elements-9064	31	29	transmission	transmission	NOUN
elements-9064	31	30	.	.	PUNCT
elements-9064	32	1	ii	ii	PROPN
elements-9064	32	2	.	.	PUNCT
elements-9064	33	1	the	the	DET
elements-9064	33	2	apobec3	apobec3	PROPN
elements-9064	33	3	subfamily	subfamily	ADV
elements-9064	33	4	:	:	PUNCT
elements-9064	33	5	a	a	DET
elements-9064	33	6	cluster	cluster	NOUN
elements-9064	33	7	of	of	ADP
elements-9064	33	8	potent	potent	ADJ
elements-9064	33	9	lentiviral	lentiviral	ADJ
elements-9064	33	10	restriction	restriction	NOUN
elements-9064	33	11	factors	factor	VERB
elements-9064	33	12	the	the	DET
elements-9064	33	13	apolipoprotein	apolipoprotein	NOUN
elements-9064	33	14	b	b	PROPN
elements-9064	33	15	mrna	mrna	NOUN
elements-9064	33	16	-	-	PUNCT
elements-9064	33	17	editing	edit	VERB
elements-9064	33	18	catalytic	catalytic	ADJ
elements-9064	33	19	polypetide-3	polypetide-3	NUM
elements-9064	33	20	(	(	PUNCT
elements-9064	33	21	apobec3	apobec3	NOUN
elements-9064	33	22	)	)	PUNCT
elements-9064	33	23	subfamily	subfamily	ADV
elements-9064	33	24	of	of	ADP
elements-9064	33	25	cytidine	cytidine	NOUN
elements-9064	33	26	deaminases	deaminase	NOUN
elements-9064	33	27	represents	represent	VERB
elements-9064	33	28	one	one	NUM
elements-9064	33	29	such	such	ADJ
elements-9064	33	30	group	group	NOUN
elements-9064	33	31	of	of	ADP
elements-9064	33	32	restriction	restriction	NOUN
elements-9064	33	33	factors	factor	NOUN
elements-9064	33	34	.	.	PUNCT
elements-9064	34	1	primates	primate	NOUN
elements-9064	34	2	encode	encode	VERB
elements-9064	34	3	seven	seven	NUM
elements-9064	34	4	apobec3	apobec3	NOUN
elements-9064	34	5	(	(	PUNCT
elements-9064	34	6	a3	a3	NOUN
elements-9064	34	7	)	)	PUNCT
elements-9064	34	8	genes	gene	NOUN
elements-9064	34	9	that	that	PRON
elements-9064	34	10	form	form	VERB
elements-9064	34	11	a	a	DET
elements-9064	34	12	cluster	cluster	NOUN
elements-9064	34	13	on	on	ADP
elements-9064	34	14	chromosome	chromosome	NOUN
elements-9064	34	15	22	22	NUM
elements-9064	34	16	in	in	ADP
elements-9064	34	17	humans	human	NOUN
elements-9064	34	18	and	and	CCONJ
elements-9064	34	19	chromosome	chromosome	VERB
elements-9064	34	20	10	10	NUM
elements-9064	34	21	in	in	ADP
elements-9064	34	22	rhesus	rhesus	NOUN
elements-9064	34	23	macaque	macaque	ADJ
elements-9064	34	24	monkeys	monkey	NOUN
elements-9064	34	25	:	:	PUNCT
elements-9064	34	26	a3a	a3a	ADJ
elements-9064	34	27	,	,	PUNCT
elements-9064	34	28	a3b	a3b	ADJ
elements-9064	34	29	,	,	PUNCT
elements-9064	34	30	a3c	a3c	NUM
elements-9064	34	31	,	,	PUNCT
elements-9064	34	32	a3d	a3d	PROPN
elements-9064	34	33	,	,	PUNCT
elements-9064	34	34	a3f	a3f	ADJ
elements-9064	34	35	,	,	PUNCT
elements-9064	34	36	a3	a3	NOUN
elements-9064	34	37	g	g	NOUN
elements-9064	34	38	,	,	PUNCT
elements-9064	34	39	and	and	CCONJ
elements-9064	34	40	50	50	NUM
elements-9064	34	41	elements	element	NOUN
elements-9064	34	42	:	:	PUNCT
elements-9064	34	43	:	:	PUNCT
elements-9064	34	44	fall	fall	VERB
elements-9064	34	45	2015	2015	NUM
elements-9064	34	46	a3h	a3h	NOUN
elements-9064	34	47	.	.	PUNCT
elements-9064	34	48	a3	a3	NOUN
elements-9064	34	49	proteins	protein	NOUN
elements-9064	34	50	are	be	AUX
elements-9064	34	51	most	most	ADV
elements-9064	34	52	highly	highly	ADV
elements-9064	34	53	expressed	express	VERB
elements-9064	34	54	in	in	ADP
elements-9064	34	55	hiv-1	hiv-1	X
elements-9064	34	56	target	target	NOUN
elements-9064	34	57	cell	cell	NOUN
elements-9064	34	58	types	type	NOUN
elements-9064	34	59	such	such	ADJ
elements-9064	34	60	as	as	ADP
elements-9064	34	61	t	t	NOUN
elements-9064	34	62	-	-	PUNCT
elements-9064	34	63	cells	cell	NOUN
elements-9064	34	64	,	,	PUNCT
elements-9064	34	65	macrophages	macrophage	NOUN
elements-9064	34	66	,	,	PUNCT
elements-9064	34	67	and	and	CCONJ
elements-9064	34	68	dendritic	dendritic	ADJ
elements-9064	34	69	cells	cell	NOUN
elements-9064	34	70	,	,	PUNCT
elements-9064	34	71	and	and	CCONJ
elements-9064	34	72	they	they	PRON
elements-9064	34	73	are	be	AUX
elements-9064	34	74	active	active	ADJ
elements-9064	34	75	in	in	ADP
elements-9064	34	76	restricting	restrict	VERB
elements-9064	34	77	retroviruses	retrovirus	NOUN
elements-9064	34	78	as	as	ADV
elements-9064	34	79	well	well	ADV
elements-9064	34	80	as	as	ADP
elements-9064	34	81	some	some	DET
elements-9064	34	82	other	other	ADJ
elements-9064	34	83	viruses	virus	NOUN
elements-9064	34	84	that	that	PRON
elements-9064	34	85	do	do	AUX
elements-9064	34	86	not	not	PART
elements-9064	34	87	replicate	replicate	VERB
elements-9064	34	88	via	via	ADP
elements-9064	34	89	reverse	reverse	ADJ
elements-9064	34	90	transcription.12,13	transcription.12,13	NOUN
elements-9064	34	91	human	human	PROPN
elements-9064	34	92	a3d	a3d	PROPN
elements-9064	34	93	,	,	PUNCT
elements-9064	34	94	a3f	a3f	ADJ
elements-9064	34	95	,	,	PUNCT
elements-9064	34	96	a3	a3	NOUN
elements-9064	34	97	g	g	NOUN
elements-9064	34	98	,	,	PUNCT
elements-9064	34	99	and	and	CCONJ
elements-9064	34	100	a3h	a3h	NOUN
elements-9064	34	101	are	be	AUX
elements-9064	34	102	known	know	VERB
elements-9064	34	103	to	to	PART
elements-9064	34	104	be	be	AUX
elements-9064	34	105	involved	involve	VERB
elements-9064	34	106	with	with	ADP
elements-9064	34	107	hiv	hiv	PROPN
elements-9064	34	108	restriction	restriction	NOUN
elements-9064	34	109	,	,	PUNCT
elements-9064	34	110	and	and	CCONJ
elements-9064	34	111	each	each	PRON
elements-9064	34	112	of	of	ADP
elements-9064	34	113	these	these	DET
elements-9064	34	114	proteins	protein	NOUN
elements-9064	34	115	has	have	VERB
elements-9064	34	116	a	a	DET
elements-9064	34	117	functionally	functionally	ADV
elements-9064	34	118	conserved	conserve	VERB
elements-9064	34	119	homolog	homolog	NOUN
elements-9064	34	120	in	in	ADP
elements-9064	34	121	rhesus	rhesus	NOUN
elements-9064	34	122	macaques.14	macaques.14	PROPN
elements-9064	34	123	the	the	DET
elements-9064	34	124	structure	structure	NOUN
elements-9064	34	125	of	of	ADP
elements-9064	34	126	a3	a3	NOUN
elements-9064	34	127	proteins	protein	NOUN
elements-9064	34	128	is	be	AUX
elements-9064	34	129	characterized	characterize	VERB
elements-9064	34	130	by	by	ADP
elements-9064	34	131	a	a	DET
elements-9064	34	132	cytidine	cytidine	NOUN
elements-9064	34	133	deaminase	deaminase	NOUN
elements-9064	34	134	domain	domain	NOUN
elements-9064	34	135	consisting	consist	VERB
elements-9064	34	136	of	of	ADP
elements-9064	34	137	six	six	NUM
elements-9064	34	138	α	α	NOUN
elements-9064	34	139	-	-	PUNCT
elements-9064	34	140	helices	helix	NOUN
elements-9064	34	141	coordinated	coordinate	VERB
elements-9064	34	142	around	around	ADP
elements-9064	34	143	five	five	NUM
elements-9064	34	144	β	β	NOUN
elements-9064	34	145	-	-	NOUN
elements-9064	34	146	strands	strand	NOUN
elements-9064	34	147	.	.	PUNCT
elements-9064	35	1	this	this	DET
elements-9064	35	2	domain	domain	NOUN
elements-9064	35	3	sits	sit	VERB
elements-9064	35	4	between	between	ADP
elements-9064	35	5	a	a	DET
elements-9064	35	6	short	short	ADJ
elements-9064	35	7	n	n	CCONJ
elements-9064	35	8	-	-	PUNCT
elements-9064	35	9	terminal	terminal	ADJ
elements-9064	35	10	α	α	ADJ
elements-9064	35	11	-	-	ADJ
elements-9064	35	12	helical	helical	ADJ
elements-9064	35	13	domain	domain	NOUN
elements-9064	35	14	and	and	CCONJ
elements-9064	35	15	a	a	DET
elements-9064	35	16	short	short	ADJ
elements-9064	35	17	c	c	NOUN
elements-9064	35	18	-	-	PUNCT
elements-9064	35	19	terminal	terminal	ADJ
elements-9064	35	20	peptide.15	peptide.15	NOUN
elements-9064	35	21	the	the	DET
elements-9064	35	22	deaminase	deaminase	NOUN
elements-9064	35	23	domain	domain	NOUN
elements-9064	35	24	contains	contain	VERB
elements-9064	35	25	a	a	DET
elements-9064	35	26	conserved	conserve	VERB
elements-9064	35	27	zincbinding	zincbinding	NOUN
elements-9064	35	28	catalytic	catalytic	ADJ
elements-9064	35	29	hxex23	hxex23	NOUN
elements-9064	35	30	-	-	PUNCT
elements-9064	35	31	28pcx2	28pcx2	NUM
elements-9064	35	32	-	-	PUNCT
elements-9064	35	33	4c	4c	NUM
elements-9064	35	34	motif	motif	NOUN
elements-9064	35	35	that	that	PRON
elements-9064	35	36	coordinates	coordinate	VERB
elements-9064	35	37	deaminase	deaminase	NOUN
elements-9064	35	38	activity	activity	NOUN
elements-9064	35	39	.	.	PUNCT
elements-9064	36	1	a3a	a3a	ADJ
elements-9064	36	2	,	,	PUNCT
elements-9064	36	3	a3c	a3c	NUM
elements-9064	36	4	,	,	PUNCT
elements-9064	36	5	and	and	CCONJ
elements-9064	36	6	a3h	a3h	NOUN
elements-9064	36	7	contain	contain	VERB
elements-9064	36	8	a	a	DET
elements-9064	36	9	single	single	ADJ
elements-9064	36	10	deaminase	deaminase	NOUN
elements-9064	36	11	domain	domain	NOUN
elements-9064	36	12	,	,	PUNCT
elements-9064	36	13	while	while	SCONJ
elements-9064	36	14	a3b	a3b	SYM
elements-9064	36	15	,	,	PUNCT
elements-9064	36	16	a3d	a3d	PROPN
elements-9064	36	17	,	,	PUNCT
elements-9064	36	18	a3f	a3f	ADJ
elements-9064	36	19	,	,	PUNCT
elements-9064	36	20	and	and	CCONJ
elements-9064	36	21	a3	a3	NOUN
elements-9064	36	22	g	g	PROPN
elements-9064	36	23	contain	contain	VERB
elements-9064	36	24	two	two	NUM
elements-9064	36	25	deaminase	deaminase	NOUN
elements-9064	36	26	domains	domain	NOUN
elements-9064	36	27	.	.	PUNCT
elements-9064	37	1	in	in	ADP
elements-9064	37	2	the	the	DET
elements-9064	37	3	four	four	NUM
elements-9064	37	4	a3s	a3s	NOUN
elements-9064	37	5	with	with	ADP
elements-9064	37	6	two	two	NUM
elements-9064	37	7	deaminase	deaminase	NOUN
elements-9064	37	8	domains	domain	NOUN
elements-9064	37	9	,	,	PUNCT
elements-9064	37	10	only	only	ADV
elements-9064	37	11	the	the	DET
elements-9064	37	12	c	c	NOUN
elements-9064	37	13	-	-	PUNCT
elements-9064	37	14	terminal	terminal	ADJ
elements-9064	37	15	domain	domain	NOUN
elements-9064	37	16	(	(	PUNCT
elements-9064	37	17	ctd	ctd	NOUN
elements-9064	37	18	)	)	PUNCT
elements-9064	37	19	is	be	AUX
elements-9064	37	20	catalytically	catalytically	NOUN
elements-9064	37	21	active.16,17	active.16,17	NOUN
elements-9064	37	22	a3	a3	NOUN
elements-9064	37	23	g	g	PROPN
elements-9064	37	24	and	and	CCONJ
elements-9064	37	25	a3f	a3f	PROPN
elements-9064	37	26	have	have	VERB
elements-9064	37	27	the	the	DET
elements-9064	37	28	greatest	great	ADJ
elements-9064	37	29	sequence	sequence	NOUN
elements-9064	37	30	similarity	similarity	NOUN
elements-9064	37	31	of	of	ADP
elements-9064	37	32	the	the	DET
elements-9064	37	33	seven	seven	NUM
elements-9064	37	34	a3s	a3s	NOUN
elements-9064	37	35	,	,	PUNCT
elements-9064	37	36	and	and	CCONJ
elements-9064	37	37	they	they	PRON
elements-9064	37	38	share	share	VERB
elements-9064	37	39	many	many	ADJ
elements-9064	37	40	structural	structural	ADJ
elements-9064	37	41	features	feature	NOUN
elements-9064	37	42	that	that	PRON
elements-9064	37	43	have	have	AUX
elements-9064	37	44	been	be	AUX
elements-9064	37	45	elucidated	elucidate	VERB
elements-9064	37	46	from	from	ADP
elements-9064	37	47	the	the	DET
elements-9064	37	48	crystal	crystal	NOUN
elements-9064	37	49	structures	structure	NOUN
elements-9064	37	50	of	of	ADP
elements-9064	37	51	their	their	PRON
elements-9064	37	52	ctds	ctds	NOUN
elements-9064	37	53	.	.	PUNCT
elements-9064	38	1	the	the	DET
elements-9064	38	2	basic	basic	ADJ
elements-9064	38	3	structure	structure	NOUN
elements-9064	38	4	is	be	AUX
elements-9064	38	5	maintained	maintain	VERB
elements-9064	38	6	between	between	ADP
elements-9064	38	7	the	the	DET
elements-9064	38	8	proteins	protein	NOUN
elements-9064	38	9	,	,	PUNCT
elements-9064	38	10	but	but	CCONJ
elements-9064	38	11	differences	difference	NOUN
elements-9064	38	12	paralleling	parallel	VERB
elements-9064	38	13	the	the	DET
elements-9064	38	14	divergence	divergence	NOUN
elements-9064	38	15	in	in	ADP
elements-9064	38	16	primary	primary	ADJ
elements-9064	38	17	structure	structure	NOUN
elements-9064	38	18	are	be	AUX
elements-9064	38	19	evident.18	evident.18	PROPN
elements-9064	38	20	a3	a3	NOUN
elements-9064	38	21	g	g	NOUN
elements-9064	38	22	is	be	AUX
elements-9064	38	23	the	the	DET
elements-9064	38	24	most	most	ADV
elements-9064	38	25	widely	widely	ADV
elements-9064	38	26	studied	study	VERB
elements-9064	38	27	of	of	ADP
elements-9064	38	28	the	the	DET
elements-9064	38	29	a3	a3	NOUN
elements-9064	38	30	subfamily	subfamily	ADV
elements-9064	38	31	,	,	PUNCT
elements-9064	38	32	as	as	SCONJ
elements-9064	38	33	it	it	PRON
elements-9064	38	34	is	be	AUX
elements-9064	38	35	believed	believe	VERB
elements-9064	38	36	to	to	PART
elements-9064	38	37	play	play	VERB
elements-9064	38	38	the	the	DET
elements-9064	38	39	largest	large	ADJ
elements-9064	38	40	role	role	NOUN
elements-9064	38	41	in	in	ADP
elements-9064	38	42	hiv-1	hiv-1	X
elements-9064	38	43	restriction.19	restriction.19	NOUN
elements-9064	38	44	however	however	ADV
elements-9064	38	45	,	,	PUNCT
elements-9064	38	46	a3d	a3d	PROPN
elements-9064	38	47	,	,	PUNCT
elements-9064	38	48	a3f	a3f	ADJ
elements-9064	38	49	,	,	PUNCT
elements-9064	38	50	and	and	CCONJ
elements-9064	38	51	a3h	a3h	NOUN
elements-9064	38	52	have	have	AUX
elements-9064	38	53	also	also	ADV
elements-9064	38	54	been	be	AUX
elements-9064	38	55	implicated	implicate	VERB
elements-9064	38	56	in	in	ADP
elements-9064	38	57	viral	viral	ADJ
elements-9064	38	58	restriction	restriction	NOUN
elements-9064	38	59	.	.	PUNCT
elements-9064	39	1	a3s	a3s	NOUN
elements-9064	39	2	act	act	NOUN
elements-9064	39	3	by	by	ADP
elements-9064	39	4	inducing	induce	VERB
elements-9064	39	5	cytidine	cytidine	NOUN
elements-9064	39	6	-	-	PUNCT
elements-9064	39	7	to	to	ADP
elements-9064	39	8	-	-	PUNCT
elements-9064	39	9	uracil	uracil	ADJ
elements-9064	39	10	mutations	mutation	NOUN
elements-9064	39	11	in	in	ADP
elements-9064	39	12	the	the	DET
elements-9064	39	13	viral	viral	ADJ
elements-9064	39	14	negative	negative	ADJ
elements-9064	39	15	sense	sense	NOUN
elements-9064	39	16	cdna	cdna	PROPN
elements-9064	39	17	produced	produce	VERB
elements-9064	39	18	during	during	ADP
elements-9064	39	19	reverse	reverse	ADJ
elements-9064	39	20	transcription	transcription	NOUN
elements-9064	39	21	,	,	PUNCT
elements-9064	39	22	consistent	consistent	ADJ
elements-9064	39	23	with	with	ADP
elements-9064	39	24	the	the	DET
elements-9064	39	25	proteins	protein	NOUN
elements-9064	39	26	’	'	PUNCT
elements-9064	39	27	known	know	VERB
elements-9064	39	28	cytidine	cytidine	NOUN
elements-9064	39	29	deaminase	deaminase	NOUN
elements-9064	39	30	function.20	function.20	PROPN
elements-9064	39	31	studies	study	NOUN
elements-9064	39	32	have	have	AUX
elements-9064	39	33	shown	show	VERB
elements-9064	39	34	a3	a3	NOUN
elements-9064	39	35	g	g	NOUN
elements-9064	39	36	to	to	PART
elements-9064	39	37	be	be	AUX
elements-9064	39	38	the	the	DET
elements-9064	39	39	more	more	ADV
elements-9064	39	40	potent	potent	ADJ
elements-9064	39	41	editor	editor	NOUN
elements-9064	39	42	in	in	ADP
elements-9064	39	43	humans	human	NOUN
elements-9064	39	44	,	,	PUNCT
elements-9064	39	45	producing	produce	VERB
elements-9064	39	46	about	about	ADP
elements-9064	39	47	10	10	NUM
elements-9064	39	48	times	time	NOUN
elements-9064	39	49	more	more	ADJ
elements-9064	39	50	mutations	mutation	NOUN
elements-9064	39	51	in	in	ADP
elements-9064	39	52	hiv-1	hiv-1	PUNCT
elements-9064	39	53	reverse	reverse	ADJ
elements-9064	39	54	transcripts	transcript	NOUN
elements-9064	39	55	than	than	ADP
elements-9064	39	56	a3f	a3f	ADJ
elements-9064	39	57	in	in	ADP
elements-9064	39	58	cell	cell	NOUN
elements-9064	39	59	culture.21	culture.21	NOUN
elements-9064	39	60	yet	yet	ADV
elements-9064	39	61	,	,	PUNCT
elements-9064	39	62	a3f	a3f	PROPN
elements-9064	39	63	is	be	AUX
elements-9064	39	64	stably	stably	ADV
elements-9064	39	65	co	co	VERB
elements-9064	39	66	-	-	VERB
elements-9064	39	67	expressed	express	VERB
elements-9064	39	68	with	with	ADP
elements-9064	39	69	a3	a3	NOUN
elements-9064	39	70	g	g	PROPN
elements-9064	39	71	in	in	ADP
elements-9064	39	72	human	human	ADJ
elements-9064	39	73	cells	cell	NOUN
elements-9064	39	74	and	and	CCONJ
elements-9064	39	75	is	be	AUX
elements-9064	39	76	also	also	ADV
elements-9064	39	77	packaged	package	VERB
elements-9064	39	78	into	into	ADP
elements-9064	39	79	hiv-1	hiv-1	PUNCT
elements-9064	39	80	virions	virion	NOUN
elements-9064	39	81	to	to	PART
elements-9064	39	82	inhibit	inhibit	VERB
elements-9064	39	83	infectivity.22	infectivity.22	NOUN
elements-9064	39	84	a3	a3	NOUN
elements-9064	39	85	g	g	PROPN
elements-9064	39	86	preferentially	preferentially	ADV
elements-9064	39	87	deaminates	deaminate	VERB
elements-9064	39	88	cytidines	cytidine	NOUN
elements-9064	39	89	on	on	ADP
elements-9064	39	90	the	the	DET
elements-9064	39	91	3	3	NUM
elements-9064	39	92	’	'	PUNCT
elements-9064	39	93	end	end	NOUN
elements-9064	39	94	of	of	ADP
elements-9064	39	95	5’-ccc-3	5’-ccc-3	NUM
elements-9064	39	96	’	'	PUNCT
elements-9064	39	97	or	or	CCONJ
elements-9064	39	98	5’-cc-3	5’-cc-3	NOUN
elements-9064	39	99	’	'	PUNCT
elements-9064	39	100	sequences	sequence	NOUN
elements-9064	39	101	,	,	PUNCT
elements-9064	39	102	while	while	SCONJ
elements-9064	39	103	a3f	a3f	ADJ
elements-9064	39	104	and	and	CCONJ
elements-9064	39	105	other	other	ADJ
elements-9064	39	106	a3	a3	NOUN
elements-9064	39	107	proteins	protein	NOUN
elements-9064	39	108	preferentially	preferentially	ADV
elements-9064	39	109	deaminate	deaminate	VERB
elements-9064	39	110	the	the	DET
elements-9064	39	111	3	3	NUM
elements-9064	39	112	’	'	PUNCT
elements-9064	39	113	cytidine	cytidine	NOUN
elements-9064	39	114	in	in	ADP
elements-9064	39	115	5’-tc-3	5’-tc-3	NOUN
elements-9064	39	116	’	'	PUNCT
elements-9064	39	117	sequences.23	sequences.23	PROPN
elements-9064	39	118	iii	iii	PROPN
elements-9064	39	119	.	.	PUNCT
elements-9064	40	1	interaction	interaction	NOUN
elements-9064	40	2	between	between	ADP
elements-9064	40	3	apobec3	apobec3	NOUN
elements-9064	40	4	and	and	CCONJ
elements-9064	40	5	vif	vif	NOUN
elements-9064	40	6	soon	soon	ADV
elements-9064	40	7	after	after	ADP
elements-9064	40	8	the	the	DET
elements-9064	40	9	discovery	discovery	NOUN
elements-9064	40	10	of	of	ADP
elements-9064	40	11	hiv-1	hiv-1	X
elements-9064	40	12	,	,	PUNCT
elements-9064	40	13	the	the	DET
elements-9064	40	14	viral	viral	ADJ
elements-9064	40	15	protein	protein	NOUN
elements-9064	40	16	termed	term	VERB
elements-9064	40	17	viral	viral	ADJ
elements-9064	40	18	infectivity	infectivity	NOUN
elements-9064	40	19	factor	factor	NOUN
elements-9064	40	20	(	(	PUNCT
elements-9064	40	21	vif	vif	NOUN
elements-9064	40	22	)	)	PUNCT
elements-9064	40	23	was	be	AUX
elements-9064	40	24	found	find	VERB
elements-9064	40	25	to	to	PART
elements-9064	40	26	be	be	AUX
elements-9064	40	27	necessary	necessary	ADJ
elements-9064	40	28	for	for	ADP
elements-9064	40	29	successful	successful	ADJ
elements-9064	40	30	infection.24	infection.24	NOUN
elements-9064	40	31	however	however	ADV
elements-9064	40	32	,	,	PUNCT
elements-9064	40	33	it	it	PRON
elements-9064	40	34	was	be	AUX
elements-9064	40	35	not	not	PART
elements-9064	40	36	necessary	necessary	ADJ
elements-9064	40	37	in	in	ADP
elements-9064	40	38	every	every	DET
elements-9064	40	39	cell	cell	NOUN
elements-9064	40	40	type	type	NOUN
elements-9064	40	41	;	;	PUNCT
elements-9064	40	42	hiv-1δvif	hiv-1δvif	NOUN
elements-9064	40	43	could	could	AUX
elements-9064	40	44	infect	infect	VERB
elements-9064	40	45	certain	certain	ADJ
elements-9064	40	46	permissive	permissive	ADJ
elements-9064	40	47	cell	cell	NOUN
elements-9064	40	48	lines	line	NOUN
elements-9064	40	49	,	,	PUNCT
elements-9064	40	50	while	while	SCONJ
elements-9064	40	51	infection	infection	NOUN
elements-9064	40	52	was	be	AUX
elements-9064	40	53	unsuccessful	unsuccessful	ADJ
elements-9064	40	54	in	in	ADP
elements-9064	40	55	others.25	others.25	NOUN
elements-9064	40	56	it	it	PRON
elements-9064	40	57	was	be	AUX
elements-9064	40	58	only	only	ADV
elements-9064	40	59	later	later	ADV
elements-9064	40	60	determined	determine	VERB
elements-9064	40	61	that	that	SCONJ
elements-9064	40	62	a3	a3	NOUN
elements-9064	40	63	proteins	protein	NOUN
elements-9064	40	64	were	be	AUX
elements-9064	40	65	responsible	responsible	ADJ
elements-9064	40	66	for	for	ADP
elements-9064	40	67	imparting	impart	VERB
elements-9064	40	68	resistance	resistance	NOUN
elements-9064	40	69	to	to	ADP
elements-9064	40	70	vif	vif	PROPN
elements-9064	40	71	-	-	PUNCT
elements-9064	40	72	deficient	deficient	ADJ
elements-9064	40	73	virus	virus	NOUN
elements-9064	40	74	in	in	ADP
elements-9064	40	75	these	these	DET
elements-9064	40	76	nonpermissive	nonpermissive	ADJ
elements-9064	40	77	cell	cell	NOUN
elements-9064	40	78	types.26	types.26	ADJ
elements-9064	40	79	vif	vif	NOUN
elements-9064	40	80	has	have	VERB
elements-9064	40	81	two	two	NUM
elements-9064	40	82	domains	domain	NOUN
elements-9064	40	83	,	,	PUNCT
elements-9064	40	84	one	one	NUM
elements-9064	40	85	crucial	crucial	ADJ
elements-9064	40	86	for	for	ADP
elements-9064	40	87	binding	bind	VERB
elements-9064	40	88	a3	a3	NOUN
elements-9064	40	89	proteins	protein	NOUN
elements-9064	40	90	and	and	CCONJ
elements-9064	40	91	one	one	NUM
elements-9064	40	92	that	that	PRON
elements-9064	40	93	contains	contain	VERB
elements-9064	40	94	a	a	DET
elements-9064	40	95	highly	highly	ADV
elements-9064	40	96	conserved	conserved	ADJ
elements-9064	40	97	sequence	sequence	NOUN
elements-9064	40	98	required	require	VERB
elements-9064	40	99	for	for	ADP
elements-9064	40	100	mediating	mediate	VERB
elements-9064	40	101	degradation.27	degradation.27	ADJ
elements-9064	40	102	vif	vif	NOUN
elements-9064	40	103	acts	act	VERB
elements-9064	40	104	by	by	ADP
elements-9064	40	105	targeting	target	VERB
elements-9064	40	106	cytoplasmic	cytoplasmic	ADJ
elements-9064	40	107	a3	a3	NOUN
elements-9064	40	108	proteins	protein	NOUN
elements-9064	40	109	for	for	ADP
elements-9064	40	110	proteosomal	proteosomal	ADJ
elements-9064	40	111	degradation	degradation	NOUN
elements-9064	40	112	(	(	PUNCT
elements-9064	40	113	figure	figure	VERB
elements-9064	40	114	1).28	1).28	NUM
elements-9064	40	115	the	the	DET
elements-9064	40	116	interaction	interaction	NOUN
elements-9064	40	117	between	between	ADP
elements-9064	40	118	a3s	a3s	PROPN
elements-9064	40	119	and	and	CCONJ
elements-9064	40	120	vif	vif	NOUN
elements-9064	40	121	is	be	AUX
elements-9064	40	122	a	a	DET
elements-9064	40	123	crucial	crucial	ADJ
elements-9064	40	124	determinant	determinant	NOUN
elements-9064	40	125	of	of	ADP
elements-9064	40	126	the	the	DET
elements-9064	40	127	species	specie	NOUN
elements-9064	40	128	specificity	specificity	NOUN
elements-9064	40	129	of	of	ADP
elements-9064	40	130	a	a	DET
elements-9064	40	131	virus	virus	NOUN
elements-9064	40	132	,	,	PUNCT
elements-9064	40	133	and	and	CCONJ
elements-9064	40	134	it	it	PRON
elements-9064	40	135	is	be	AUX
elements-9064	40	136	likely	likely	ADJ
elements-9064	40	137	that	that	SCONJ
elements-9064	40	138	a	a	DET
elements-9064	40	139	vif	vif	NOUN
elements-9064	40	140	from	from	ADP
elements-9064	40	141	a	a	DET
elements-9064	40	142	given	give	VERB
elements-9064	40	143	viral	viral	ADJ
elements-9064	40	144	strain	strain	NOUN
elements-9064	40	145	has	have	AUX
elements-9064	40	146	evolved	evolve	VERB
elements-9064	40	147	precisely	precisely	ADV
elements-9064	40	148	to	to	PART
elements-9064	40	149	counteract	counteract	VERB
elements-9064	40	150	the	the	DET
elements-9064	40	151	a3	a3	NOUN
elements-9064	40	152	proteins	protein	NOUN
elements-9064	40	153	of	of	ADP
elements-9064	40	154	its	its	PRON
elements-9064	40	155	host	host	NOUN
elements-9064	40	156	species.29,30	species.29,30	NOUN
elements-9064	40	157	the	the	DET
elements-9064	40	158	critical	critical	ADJ
elements-9064	40	159	sites	site	NOUN
elements-9064	40	160	involved	involve	VERB
elements-9064	40	161	in	in	ADP
elements-9064	40	162	a3	a3	NOUN
elements-9064	40	163	-	-	PUNCT
elements-9064	40	164	vif	vif	NOUN
elements-9064	40	165	interactions	interaction	NOUN
elements-9064	40	166	have	have	AUX
elements-9064	40	167	largely	largely	ADV
elements-9064	40	168	been	be	AUX
elements-9064	40	169	elucidated	elucidate	VERB
elements-9064	40	170	via	via	ADP
elements-9064	40	171	mutagenesis	mutagenesis	NOUN
elements-9064	40	172	studies	study	NOUN
elements-9064	40	173	,	,	PUNCT
elements-9064	40	174	and	and	CCONJ
elements-9064	40	175	as	as	ADV
elements-9064	40	176	little	little	ADJ
elements-9064	40	177	as	as	ADP
elements-9064	40	178	a	a	DET
elements-9064	40	179	single	single	ADJ
elements-9064	40	180	amino	amino	NOUN
elements-9064	40	181	acid	acid	NOUN
elements-9064	40	182	can	can	AUX
elements-9064	40	183	be	be	AUX
elements-9064	40	184	responsible	responsible	ADJ
elements-9064	40	185	for	for	ADP
elements-9064	40	186	conferring	confer	VERB
elements-9064	40	187	the	the	DET
elements-9064	40	188	ability	ability	NOUN
elements-9064	40	189	of	of	ADP
elements-9064	40	190	a3	a3	NOUN
elements-9064	40	191	proteins	protein	NOUN
elements-9064	40	192	to	to	PART
elements-9064	40	193	resist	resist	VERB
elements-9064	40	194	degradation	degradation	NOUN
elements-9064	40	195	by	by	ADP
elements-9064	40	196	vif	vif	PROPN
elements-9064	40	197	.	.	PROPN
elements-9064	41	1	in	in	ADP
elements-9064	41	2	a3	a3	PROPN
elements-9064	41	3	g	g	PROPN
elements-9064	41	4	,	,	PUNCT
elements-9064	41	5	the	the	DET
elements-9064	41	6	vif	vif	NOUN
elements-9064	41	7	binding	bind	VERB
elements-9064	41	8	site	site	NOUN
elements-9064	41	9	has	have	AUX
elements-9064	41	10	been	be	AUX
elements-9064	41	11	localized	localize	VERB
elements-9064	41	12	to	to	ADP
elements-9064	41	13	the	the	DET
elements-9064	41	14	n	n	CCONJ
elements-9064	41	15	-	-	PUNCT
elements-9064	41	16	terminal	terminal	ADJ
elements-9064	41	17	deaminase	deaminase	NOUN
elements-9064	41	18	domain	domain	NOUN
elements-9064	41	19	(	(	PUNCT
elements-9064	41	20	ntd	ntd	NOUN
elements-9064	41	21	)	)	PUNCT
elements-9064	41	22	.	.	PUNCT
elements-9064	42	1	it	it	PRON
elements-9064	42	2	was	be	AUX
elements-9064	42	3	found	find	VERB
elements-9064	42	4	that	that	SCONJ
elements-9064	42	5	the	the	DET
elements-9064	42	6	vif	vif	NOUN
elements-9064	42	7	of	of	ADP
elements-9064	42	8	an	an	DET
elements-9064	42	9	siv	siv	NOUN
elements-9064	42	10	strain	strain	NOUN
elements-9064	42	11	isolated	isolate	VERB
elements-9064	42	12	from	from	ADP
elements-9064	42	13	african	african	ADJ
elements-9064	42	14	green	green	ADJ
elements-9064	42	15	monkeys	monkey	NOUN
elements-9064	42	16	(	(	PUNCT
elements-9064	42	17	sivagm	sivagm	NOUN
elements-9064	42	18	)	)	PUNCT
elements-9064	42	19	was	be	AUX
elements-9064	42	20	inactive	inactive	ADJ
elements-9064	42	21	against	against	ADP
elements-9064	42	22	human	human	ADJ
elements-9064	42	23	a3	a3	NOUN
elements-9064	42	24	g	g	PROPN
elements-9064	42	25	(	(	PUNCT
elements-9064	42	26	ha3	ha3	PROPN
elements-9064	42	27	g	g	NOUN
elements-9064	42	28	)	)	PUNCT
elements-9064	42	29	but	but	CCONJ
elements-9064	42	30	active	active	ADJ
elements-9064	42	31	against	against	ADP
elements-9064	42	32	african	african	ADJ
elements-9064	42	33	green	green	PROPN
elements-9064	42	34	monkey	monkey	NOUN
elements-9064	42	35	a3	a3	NOUN
elements-9064	42	36	g	g	PROPN
elements-9064	42	37	(	(	PUNCT
elements-9064	42	38	agma3	agma3	NOUN
elements-9064	42	39	g	g	NOUN
elements-9064	42	40	)	)	PUNCT
elements-9064	42	41	.	.	PUNCT
elements-9064	43	1	this	this	DET
elements-9064	43	2	discrepancy	discrepancy	NOUN
elements-9064	43	3	was	be	AUX
elements-9064	43	4	mapped	map	VERB
elements-9064	43	5	to	to	ADP
elements-9064	43	6	amino	amino	NOUN
elements-9064	43	7	acid	acid	NOUN
elements-9064	43	8	128	128	NUM
elements-9064	43	9	,	,	PUNCT
elements-9064	43	10	an	an	DET
elements-9064	43	11	aspartic	aspartic	ADJ
elements-9064	43	12	acid	acid	NOUN
elements-9064	43	13	in	in	ADP
elements-9064	43	14	ha3	ha3	PROPN
elements-9064	43	15	g	g	NOUN
elements-9064	43	16	and	and	CCONJ
elements-9064	43	17	a	a	DET
elements-9064	43	18	lysine	lysine	NOUN
elements-9064	43	19	in	in	ADP
elements-9064	43	20	agma3g.31	agma3g.31	PROPN
elements-9064	43	21	this	this	DET
elements-9064	43	22	interface	interface	NOUN
elements-9064	43	23	was	be	AUX
elements-9064	43	24	expanded	expand	VERB
elements-9064	43	25	upon	upon	SCONJ
elements-9064	43	26	to	to	PART
elements-9064	43	27	include	include	VERB
elements-9064	43	28	the	the	DET
elements-9064	43	29	proline	proline	NOUN
elements-9064	43	30	at	at	ADP
elements-9064	43	31	position	position	NOUN
elements-9064	43	32	129	129	NUM
elements-9064	43	33	and	and	CCONJ
elements-9064	43	34	the	the	DET
elements-9064	43	35	aspartic	aspartic	ADJ
elements-9064	43	36	acid	acid	NOUN
elements-9064	43	37	at	at	ADP
elements-9064	43	38	position	position	NOUN
elements-9064	43	39	130	130	NUM
elements-9064	43	40	.	.	PUNCT
elements-9064	44	1	together	together	ADV
elements-9064	44	2	,	,	PUNCT
elements-9064	44	3	these	these	DET
elements-9064	44	4	three	three	NUM
elements-9064	44	5	residues	residue	NOUN
elements-9064	44	6	create	create	VERB
elements-9064	44	7	a	a	DET
elements-9064	44	8	crucial	crucial	ADJ
elements-9064	44	9	negatively	negatively	ADV
elements-9064	44	10	charged	charge	VERB
elements-9064	44	11	binding	bind	VERB
elements-9064	44	12	surface	surface	NOUN
elements-9064	44	13	for	for	ADP
elements-9064	44	14	hiv-1	hiv-1	X
elements-9064	44	15	vif	vif	NOUN
elements-9064	44	16	in	in	ADP
elements-9064	44	17	ha3g.32	ha3g.32	PROPN
elements-9064	44	18	contrary	contrary	ADV
elements-9064	44	19	to	to	PART
elements-9064	44	20	a3	a3	VERB
elements-9064	44	21	g	g	PROPN
elements-9064	44	22	,	,	PUNCT
elements-9064	44	23	the	the	DET
elements-9064	44	24	hiv-1	hiv-1	X
elements-9064	44	25	vif	vif	NOUN
elements-9064	44	26	binding	bind	VERB
elements-9064	44	27	site	site	NOUN
elements-9064	44	28	in	in	ADP
elements-9064	44	29	a3f	a3f	PROPN
elements-9064	44	30	is	be	AUX
elements-9064	44	31	localized	localize	VERB
elements-9064	44	32	at	at	ADP
elements-9064	44	33	the	the	DET
elements-9064	44	34	ctd	ctd	NOUN
elements-9064	44	35	.	.	PUNCT
elements-9064	45	1	the	the	DET
elements-9064	45	2	region	region	NOUN
elements-9064	45	3	comprising	comprise	VERB
elements-9064	45	4	amino	amino	ADJ
elements-9064	45	5	acids	acid	NOUN
elements-9064	45	6	289eflarh294	289eflarh294	NUM
elements-9064	45	7	in	in	ADP
elements-9064	45	8	ha3f	ha3f	PROPN
elements-9064	45	9	and	and	CCONJ
elements-9064	45	10	agma3f	agma3f	PROPN
elements-9064	45	11	has	have	AUX
elements-9064	45	12	been	be	AUX
elements-9064	45	13	shown	show	VERB
elements-9064	45	14	to	to	PART
elements-9064	45	15	be	be	AUX
elements-9064	45	16	a	a	DET
elements-9064	45	17	critical	critical	ADJ
elements-9064	45	18	region	region	NOUN
elements-9064	45	19	for	for	ADP
elements-9064	45	20	hiv-1	hiv-1	PUNCT
elements-9064	45	21	vif	vif	NOUN
elements-9064	45	22	interaction.33	interaction.33	NOUN
elements-9064	45	23	another	another	DET
elements-9064	45	24	study	study	NOUN
elements-9064	45	25	suggested	suggest	VERB
elements-9064	45	26	that	that	SCONJ
elements-9064	45	27	amino	amino	NOUN
elements-9064	45	28	acid	acid	NOUN
elements-9064	45	29	324	324	NUM
elements-9064	45	30	is	be	AUX
elements-9064	45	31	a	a	DET
elements-9064	45	32	critical	critical	ADJ
elements-9064	45	33	residue	residue	NOUN
elements-9064	45	34	that	that	PRON
elements-9064	45	35	confers	confer	NOUN
elements-9064	45	36	ha3f	ha3f	VERB
elements-9064	45	37	susceptibility	susceptibility	NOUN
elements-9064	45	38	to	to	ADP
elements-9064	45	39	hiv-1	hiv-1	X
elements-9064	45	40	vif	vif	NOUN
elements-9064	45	41	and	and	CCONJ
elements-9064	45	42	rhesus	rhesus	NOUN
elements-9064	45	43	macaque	macaque	ADJ
elements-9064	45	44	a3f	a3f	PROPN
elements-9064	45	45	(	(	PUNCT
elements-9064	45	46	rha3f	rha3f	PROPN
elements-9064	45	47	)	)	PUNCT
elements-9064	45	48	resistance	resistance	NOUN
elements-9064	45	49	to	to	ADP
elements-9064	45	50	hiv-1	hiv-1	X
elements-9064	45	51	vif.34	vif.34	ADV
elements-9064	45	52	more	more	ADV
elements-9064	45	53	recently	recently	ADV
elements-9064	45	54	,	,	PUNCT
elements-9064	45	55	the	the	DET
elements-9064	45	56	negatively	negatively	ADV
elements-9064	45	57	charged	charge	VERB
elements-9064	45	58	surface	surface	NOUN
elements-9064	45	59	of	of	ADP
elements-9064	45	60	α	α	NOUN
elements-9064	45	61	-	-	PUNCT
elements-9064	45	62	helices	helix	NOUN
elements-9064	45	63	3	3	NUM
elements-9064	45	64	and	and	CCONJ
elements-9064	45	65	4	4	NUM
elements-9064	45	66	in	in	ADP
elements-9064	45	67	ha3f	ha3f	PROPN
elements-9064	45	68	has	have	AUX
elements-9064	45	69	been	be	AUX
elements-9064	45	70	strongly	strongly	ADV
elements-9064	45	71	implicated	implicate	VERB
elements-9064	45	72	in	in	ADP
elements-9064	45	73	hiv-1	hiv-1	X
elements-9064	45	74	vif	vif	NOUN
elements-9064	45	75	binding.35	binding.35	NOUN
elements-9064	45	76	in	in	ADP
elements-9064	45	77	hiv-1	hiv-1	PUNCT
elements-9064	45	78	vif	vif	NOUN
elements-9064	45	79	,	,	PUNCT
elements-9064	45	80	“	"	PUNCT
elements-9064	45	81	thus	thus	ADV
elements-9064	45	82	,	,	PUNCT
elements-9064	45	83	over	over	ADP
elements-9064	45	84	evolutionary	evolutionary	ADJ
elements-9064	45	85	time	time	NOUN
elements-9064	45	86	,	,	PUNCT
elements-9064	45	87	a	a	DET
elements-9064	45	88	comparatively	comparatively	ADV
elements-9064	45	89	large	large	ADJ
elements-9064	45	90	number	number	NOUN
elements-9064	45	91	of	of	ADP
elements-9064	45	92	non	non	ADJ
elements-9064	45	93	-	-	ADJ
elements-9064	45	94	synonymous	synonymous	ADJ
elements-9064	45	95	,	,	PUNCT
elements-9064	45	96	or	or	CCONJ
elements-9064	45	97	protein	protein	NOUN
elements-9064	45	98	-	-	PUNCT
elements-9064	45	99	altering	alter	VERB
elements-9064	45	100	,	,	PUNCT
elements-9064	45	101	mutations	mutation	NOUN
elements-9064	45	102	will	will	AUX
elements-9064	45	103	be	be	AUX
elements-9064	45	104	evident	evident	ADJ
elements-9064	45	105	in	in	ADP
elements-9064	45	106	genes	gene	NOUN
elements-9064	45	107	that	that	PRON
elements-9064	45	108	have	have	AUX
elements-9064	45	109	participated	participate	VERB
elements-9064	45	110	in	in	ADP
elements-9064	45	111	these	these	DET
elements-9064	45	112	virus	virus	NOUN
elements-9064	45	113	-	-	PUNCT
elements-9064	45	114	host	host	NOUN
elements-9064	45	115	‘	'	PUNCT
elements-9064	45	116	arms	arm	NOUN
elements-9064	45	117	races	race	NOUN
elements-9064	45	118	.	.	PUNCT
elements-9064	45	119	’	'	PUNCT
elements-9064	45	120	”	"	PUNCT
elements-9064	46	1	51	51	NUM
elements-9064	46	2	a	a	DET
elements-9064	46	3	biological	biological	ADJ
elements-9064	46	4	“	"	PUNCT
elements-9064	46	5	arms	arm	NOUN
elements-9064	46	6	race	race	NOUN
elements-9064	46	7	”	"	PUNCT
elements-9064	46	8	highly	highly	ADV
elements-9064	46	9	conserved	conserved	ADJ
elements-9064	46	10	n	n	CCONJ
elements-9064	46	11	-	-	PUNCT
elements-9064	46	12	terminal	terminal	ADJ
elements-9064	46	13	motifs	motif	NOUN
elements-9064	46	14	are	be	AUX
elements-9064	46	15	involved	involve	VERB
elements-9064	46	16	with	with	ADP
elements-9064	46	17	a3	a3	NOUN
elements-9064	46	18	g	g	PROPN
elements-9064	46	19	and	and	CCONJ
elements-9064	46	20	a3f	a3f	PROPN
elements-9064	46	21	binding.36,37	binding.36,37	NOUN
elements-9064	46	22	iv	iv	X
elements-9064	46	23	.	.	PUNCT
elements-9064	46	24	objective	objective	ADJ
elements-9064	46	25	while	while	SCONJ
elements-9064	46	26	much	much	ADJ
elements-9064	46	27	attention	attention	NOUN
elements-9064	46	28	has	have	AUX
elements-9064	46	29	been	be	AUX
elements-9064	46	30	given	give	VERB
elements-9064	46	31	to	to	ADP
elements-9064	46	32	the	the	DET
elements-9064	46	33	primary	primary	ADJ
elements-9064	46	34	structures	structure	NOUN
elements-9064	46	35	of	of	ADP
elements-9064	46	36	a3s	a3s	NOUN
elements-9064	46	37	in	in	ADP
elements-9064	46	38	terms	term	NOUN
elements-9064	46	39	of	of	ADP
elements-9064	46	40	their	their	PRON
elements-9064	46	41	effect	effect	NOUN
elements-9064	46	42	on	on	ADP
elements-9064	46	43	cross	cross	ADJ
elements-9064	46	44	-	-	ADJ
elements-9064	46	45	species	species	ADJ
elements-9064	46	46	transmission	transmission	NOUN
elements-9064	46	47	of	of	ADP
elements-9064	46	48	primate	primate	NOUN
elements-9064	46	49	lentiviruses	lentiviruse	NOUN
elements-9064	46	50	,	,	PUNCT
elements-9064	46	51	examination	examination	NOUN
elements-9064	46	52	of	of	ADP
elements-9064	46	53	the	the	DET
elements-9064	46	54	diversity	diversity	NOUN
elements-9064	46	55	in	in	ADP
elements-9064	46	56	these	these	DET
elements-9064	46	57	genes	gene	NOUN
elements-9064	46	58	has	have	AUX
elements-9064	46	59	been	be	AUX
elements-9064	46	60	largely	largely	ADV
elements-9064	46	61	unconsidered	unconsidered	ADJ
elements-9064	46	62	.	.	PUNCT
elements-9064	47	1	the	the	DET
elements-9064	47	2	most	most	ADV
elements-9064	47	3	widely	widely	ADV
elements-9064	47	4	utilized	utilize	VERB
elements-9064	47	5	primate	primate	NOUN
elements-9064	47	6	model	model	NOUN
elements-9064	47	7	for	for	ADP
elements-9064	47	8	investigating	investigate	VERB
elements-9064	47	9	lentiviral	lentiviral	ADJ
elements-9064	47	10	infection	infection	NOUN
elements-9064	47	11	and	and	CCONJ
elements-9064	47	12	disease	disease	NOUN
elements-9064	47	13	is	be	AUX
elements-9064	47	14	the	the	DET
elements-9064	47	15	siv	siv	PROPN
elements-9064	47	16	infecting	infect	VERB
elements-9064	47	17	rhesus	rhesus	NOUN
elements-9064	47	18	macaques	macaque	NOUN
elements-9064	47	19	(	(	PUNCT
elements-9064	47	20	sivmac	sivmac	PROPN
elements-9064	47	21	)	)	PUNCT
elements-9064	47	22	,	,	PUNCT
elements-9064	47	23	with	with	ADP
elements-9064	47	24	rhesus	rhesus	NOUN
elements-9064	47	25	macaques	macaque	NOUN
elements-9064	47	26	of	of	ADP
elements-9064	47	27	indian	indian	ADJ
elements-9064	47	28	origin	origin	NOUN
elements-9064	47	29	being	be	AUX
elements-9064	47	30	the	the	DET
elements-9064	47	31	best	well	ADV
elements-9064	47	32	characterized	characterized	ADJ
elements-9064	47	33	species.38	species.38	NOUN
elements-9064	47	34	rhesus	rhesus	NOUN
elements-9064	47	35	macaques	macaque	NOUN
elements-9064	47	36	are	be	AUX
elements-9064	47	37	not	not	PART
elements-9064	47	38	natural	natural	ADJ
elements-9064	47	39	hosts	host	NOUN
elements-9064	47	40	of	of	ADP
elements-9064	47	41	siv	siv	PROPN
elements-9064	47	42	in	in	ADP
elements-9064	47	43	the	the	DET
elements-9064	47	44	wild	wild	NOUN
elements-9064	47	45	;	;	PUNCT
elements-9064	47	46	rather	rather	ADV
elements-9064	47	47	,	,	PUNCT
elements-9064	47	48	sivmac	sivmac	PROPN
elements-9064	47	49	emerged	emerge	VERB
elements-9064	47	50	from	from	ADP
elements-9064	47	51	cross	cross	ADJ
elements-9064	47	52	-	-	ADJ
elements-9064	47	53	species	species	ADJ
elements-9064	47	54	transmission	transmission	NOUN
elements-9064	47	55	events	event	NOUN
elements-9064	47	56	in	in	ADP
elements-9064	47	57	us	us	PROPN
elements-9064	47	58	primate	primate	NOUN
elements-9064	47	59	centers	center	NOUN
elements-9064	47	60	and	and	CCONJ
elements-9064	47	61	likely	likely	ADV
elements-9064	47	62	originated	originate	VERB
elements-9064	47	63	from	from	ADP
elements-9064	47	64	infected	infected	ADJ
elements-9064	47	65	sooty	sooty	NOUN
elements-9064	47	66	mangabeys.39,40	mangabeys.39,40	VERB
elements-9064	47	67	the	the	DET
elements-9064	47	68	adaptations	adaptation	NOUN
elements-9064	47	69	allowing	allow	VERB
elements-9064	47	70	the	the	DET
elements-9064	47	71	virus	virus	NOUN
elements-9064	47	72	to	to	PART
elements-9064	47	73	stably	stably	ADV
elements-9064	47	74	infect	infect	VERB
elements-9064	47	75	rhesus	rhesus	NOUN
elements-9064	47	76	macaques	macaque	NOUN
elements-9064	47	77	likely	likely	ADV
elements-9064	47	78	occurred	occur	VERB
elements-9064	47	79	as	as	ADP
elements-9064	47	80	a	a	DET
elements-9064	47	81	result	result	NOUN
elements-9064	47	82	of	of	ADP
elements-9064	47	83	serial	serial	ADJ
elements-9064	47	84	passages	passage	NOUN
elements-9064	47	85	of	of	ADP
elements-9064	47	86	the	the	DET
elements-9064	47	87	virus	virus	NOUN
elements-9064	47	88	through	through	ADP
elements-9064	47	89	multiple	multiple	ADJ
elements-9064	47	90	animals.41	animals.41	NOUN
elements-9064	47	91	unlike	unlike	ADP
elements-9064	47	92	sivsm	sivsm	NOUN
elements-9064	47	93	in	in	ADP
elements-9064	47	94	its	its	PRON
elements-9064	47	95	natural	natural	ADJ
elements-9064	47	96	host	host	NOUN
elements-9064	47	97	,	,	PUNCT
elements-9064	47	98	sivmac	sivmac	PROPN
elements-9064	47	99	is	be	AUX
elements-9064	47	100	pathogenic	pathogenic	ADJ
elements-9064	47	101	in	in	ADP
elements-9064	47	102	rhesus	rhesus	NOUN
elements-9064	47	103	macaques	macaque	NOUN
elements-9064	47	104	,	,	PUNCT
elements-9064	47	105	resulting	result	VERB
elements-9064	47	106	in	in	ADP
elements-9064	47	107	an	an	DET
elements-9064	47	108	aids	aid	NOUN
elements-9064	47	109	-	-	PUNCT
elements-9064	47	110	like	like	ADJ
elements-9064	47	111	disease	disease	NOUN
elements-9064	47	112	.	.	PUNCT
elements-9064	48	1	given	give	VERB
elements-9064	48	2	the	the	DET
elements-9064	48	3	well	well	ADV
elements-9064	48	4	-	-	PUNCT
elements-9064	48	5	established	establish	VERB
elements-9064	48	6	history	history	NOUN
elements-9064	48	7	of	of	ADP
elements-9064	48	8	its	its	PRON
elements-9064	48	9	emergence	emergence	NOUN
elements-9064	48	10	,	,	PUNCT
elements-9064	48	11	sivmac	sivmac	PROPN
elements-9064	48	12	is	be	AUX
elements-9064	48	13	an	an	DET
elements-9064	48	14	excellent	excellent	ADJ
elements-9064	48	15	model	model	NOUN
elements-9064	48	16	for	for	ADP
elements-9064	48	17	studying	study	VERB
elements-9064	48	18	the	the	DET
elements-9064	48	19	adaptive	adaptive	ADJ
elements-9064	48	20	processes	process	NOUN
elements-9064	48	21	that	that	PRON
elements-9064	48	22	viruses	virus	NOUN
elements-9064	48	23	must	must	AUX
elements-9064	48	24	undergo	undergo	VERB
elements-9064	48	25	in	in	ADP
elements-9064	48	26	order	order	NOUN
elements-9064	48	27	to	to	PART
elements-9064	48	28	successfully	successfully	ADV
elements-9064	48	29	infect	infect	VERB
elements-9064	48	30	a	a	DET
elements-9064	48	31	new	new	ADJ
elements-9064	48	32	host	host	NOUN
elements-9064	48	33	species	specie	NOUN
elements-9064	48	34	.	.	PUNCT
elements-9064	49	1	recent	recent	ADJ
elements-9064	49	2	work	work	NOUN
elements-9064	49	3	has	have	AUX
elements-9064	49	4	demonstrated	demonstrate	VERB
elements-9064	49	5	that	that	SCONJ
elements-9064	49	6	the	the	DET
elements-9064	49	7	rhesus	rhesus	NOUN
elements-9064	49	8	macaque	macaque	ADJ
elements-9064	49	9	a3	a3	PROPN
elements-9064	49	10	g	g	NOUN
elements-9064	49	11	gene	gene	NOUN
elements-9064	49	12	(	(	PUNCT
elements-9064	49	13	rha3	rha3	PROPN
elements-9064	49	14	g	g	NOUN
elements-9064	49	15	)	)	PUNCT
elements-9064	49	16	is	be	AUX
elements-9064	49	17	polymorphic	polymorphic	ADJ
elements-9064	49	18	at	at	ADP
elements-9064	49	19	an	an	DET
elements-9064	49	20	n	n	CCONJ
elements-9064	49	21	-	-	PUNCT
elements-9064	49	22	terminal	terminal	ADJ
elements-9064	49	23	site	site	NOUN
elements-9064	49	24	,	,	PUNCT
elements-9064	49	25	where	where	SCONJ
elements-9064	49	26	three	three	NUM
elements-9064	49	27	sequence	sequence	NOUN
elements-9064	49	28	variations	variation	NOUN
elements-9064	49	29	are	be	AUX
elements-9064	49	30	apparent	apparent	ADJ
elements-9064	49	31	.	.	PUNCT
elements-9064	50	1	the	the	DET
elements-9064	50	2	variants	variant	NOUN
elements-9064	50	3	displayed	display	VERB
elements-9064	50	4	differential	differential	ADJ
elements-9064	50	5	susceptibilities	susceptibility	NOUN
elements-9064	50	6	to	to	ADP
elements-9064	50	7	sivsm	sivsm	NOUN
elements-9064	50	8	vifmediated	vifmediate	VERB
elements-9064	50	9	degradation	degradation	NOUN
elements-9064	50	10	in	in	ADP
elements-9064	50	11	cell	cell	NOUN
elements-9064	50	12	culture	culture	NOUN
elements-9064	50	13	,	,	PUNCT
elements-9064	50	14	but	but	CCONJ
elements-9064	50	15	all	all	DET
elements-9064	50	16	three	three	NUM
elements-9064	50	17	could	could	AUX
elements-9064	50	18	be	be	AUX
elements-9064	50	19	degraded	degrade	VERB
elements-9064	50	20	by	by	ADP
elements-9064	50	21	sivmac	sivmac	PROPN
elements-9064	50	22	vif.42	vif.42	NOUN
elements-9064	50	23	thus	thus	ADV
elements-9064	50	24	,	,	PUNCT
elements-9064	50	25	it	it	PRON
elements-9064	50	26	is	be	AUX
elements-9064	50	27	likely	likely	ADJ
elements-9064	50	28	that	that	SCONJ
elements-9064	50	29	sivmac	sivmac	PROPN
elements-9064	50	30	vif	vif	PROPN
elements-9064	50	31	had	have	VERB
elements-9064	50	32	to	to	PART
elements-9064	50	33	adapt	adapt	VERB
elements-9064	50	34	to	to	PART
elements-9064	50	35	counteract	counteract	VERB
elements-9064	50	36	the	the	DET
elements-9064	50	37	sivsm	sivsm	NOUN
elements-9064	50	38	vif	vif	NOUN
elements-9064	50	39	-	-	ADJ
elements-9064	50	40	resistant	resistant	ADJ
elements-9064	50	41	rhesus	rhesus	NOUN
elements-9064	50	42	macaque	macaque	PROPN
elements-9064	50	43	a3	a3	NOUN
elements-9064	50	44	g	g	NOUN
elements-9064	50	45	allele	allele	NOUN
elements-9064	50	46	in	in	ADP
elements-9064	50	47	order	order	NOUN
elements-9064	50	48	for	for	SCONJ
elements-9064	50	49	pathogenic	pathogenic	ADJ
elements-9064	50	50	sivmac	sivmac	NOUN
elements-9064	50	51	to	to	PART
elements-9064	50	52	emerge	emerge	VERB
elements-9064	50	53	.	.	PUNCT
elements-9064	51	1	it	it	PRON
elements-9064	51	2	is	be	AUX
elements-9064	51	3	also	also	ADV
elements-9064	51	4	known	know	VERB
elements-9064	51	5	that	that	SCONJ
elements-9064	51	6	a3	a3	NOUN
elements-9064	51	7	g	g	PROPN
elements-9064	51	8	has	have	AUX
elements-9064	51	9	evolved	evolve	VERB
elements-9064	51	10	under	under	ADP
elements-9064	51	11	strong	strong	ADJ
elements-9064	51	12	positive	positive	ADJ
elements-9064	51	13	selection	selection	NOUN
elements-9064	51	14	,	,	PUNCT
elements-9064	51	15	and	and	CCONJ
elements-9064	51	16	that	that	SCONJ
elements-9064	51	17	vif	vif	NOUN
elements-9064	51	18	is	be	AUX
elements-9064	51	19	not	not	PART
elements-9064	51	20	wholly	wholly	ADV
elements-9064	51	21	responsible	responsible	ADJ
elements-9064	51	22	for	for	ADP
elements-9064	51	23	this	this	DET
elements-9064	51	24	phenomenon.43	phenomenon.43	NOUN
elements-9064	51	25	the	the	DET
elements-9064	51	26	present	present	ADJ
elements-9064	51	27	study	study	NOUN
elements-9064	51	28	is	be	AUX
elements-9064	51	29	intended	intend	VERB
elements-9064	51	30	to	to	PART
elements-9064	51	31	further	far	ADV
elements-9064	51	32	characterize	characterize	VERB
elements-9064	51	33	the	the	DET
elements-9064	51	34	degree	degree	NOUN
elements-9064	51	35	of	of	ADP
elements-9064	51	36	variation	variation	NOUN
elements-9064	51	37	in	in	ADP
elements-9064	51	38	other	other	ADJ
elements-9064	51	39	a3	a3	NOUN
elements-9064	51	40	family	family	NOUN
elements-9064	51	41	members	member	NOUN
elements-9064	51	42	,	,	PUNCT
elements-9064	51	43	more	more	ADV
elements-9064	51	44	specifically	specifically	ADV
elements-9064	51	45	a3f	a3f	ADJ
elements-9064	51	46	.	.	PUNCT
elements-9064	52	1	old	old	ADJ
elements-9064	52	2	world	world	NOUN
elements-9064	52	3	primate	primate	NOUN
elements-9064	52	4	a3fs	a3fs	PUNCT
elements-9064	52	5	were	be	AUX
elements-9064	52	6	examined	examine	VERB
elements-9064	52	7	for	for	ADP
elements-9064	52	8	the	the	DET
elements-9064	52	9	genetic	genetic	ADJ
elements-9064	52	10	signatures	signature	NOUN
elements-9064	52	11	of	of	ADP
elements-9064	52	12	a	a	DET
elements-9064	52	13	rapidly	rapidly	ADV
elements-9064	52	14	adapting	adapt	VERB
elements-9064	52	15	restriction	restriction	NOUN
elements-9064	52	16	factor	factor	NOUN
elements-9064	52	17	.	.	PUNCT
elements-9064	53	1	in	in	ADP
elements-9064	53	2	a	a	DET
elements-9064	53	3	manner	manner	NOUN
elements-9064	53	4	analogous	analogous	ADJ
elements-9064	53	5	to	to	PART
elements-9064	53	6	a3	a3	VERB
elements-9064	53	7	g	g	NOUN
elements-9064	53	8	,	,	PUNCT
elements-9064	53	9	polymorphic	polymorphic	ADJ
elements-9064	53	10	sites	site	NOUN
elements-9064	53	11	in	in	ADP
elements-9064	53	12	a3f	a3f	PROPN
elements-9064	53	13	may	may	AUX
elements-9064	53	14	indicate	indicate	VERB
elements-9064	53	15	potential	potential	ADJ
elements-9064	53	16	determinants	determinant	NOUN
elements-9064	53	17	of	of	ADP
elements-9064	53	18	the	the	DET
elements-9064	53	19	ability	ability	NOUN
elements-9064	53	20	of	of	ADP
elements-9064	53	21	sivmac	sivmac	NOUN
elements-9064	53	22	to	to	PART
elements-9064	53	23	infect	infect	VERB
elements-9064	53	24	its	its	PRON
elements-9064	53	25	novel	novel	ADJ
elements-9064	53	26	host	host	NOUN
elements-9064	53	27	.	.	PUNCT
elements-9064	54	1	polymorphic	polymorphic	ADJ
elements-9064	54	2	sites	site	NOUN
elements-9064	54	3	were	be	AUX
elements-9064	54	4	investigated	investigate	VERB
elements-9064	54	5	for	for	ADP
elements-9064	54	6	their	their	PRON
elements-9064	54	7	potential	potential	ADJ
elements-9064	54	8	influence	influence	NOUN
elements-9064	54	9	on	on	ADP
elements-9064	54	10	the	the	DET
elements-9064	54	11	ability	ability	NOUN
elements-9064	54	12	of	of	ADP
elements-9064	54	13	rha3f	rha3f	PROPN
elements-9064	54	14	to	to	PART
elements-9064	54	15	resist	resist	VERB
elements-9064	54	16	degradation	degradation	NOUN
elements-9064	54	17	by	by	ADP
elements-9064	54	18	vifs	vif	NOUN
elements-9064	54	19	derived	derive	VERB
elements-9064	54	20	from	from	ADP
elements-9064	54	21	various	various	ADJ
elements-9064	54	22	siv	siv	PROPN
elements-9064	54	23	strains	strain	NOUN
elements-9064	54	24	.	.	PUNCT
elements-9064	55	1	examination	examination	NOUN
elements-9064	55	2	of	of	ADP
elements-9064	55	3	allelic	allelic	ADJ
elements-9064	55	4	variance	variance	NOUN
elements-9064	55	5	in	in	ADP
elements-9064	55	6	a3f	a3f	PROPN
elements-9064	55	7	provides	provide	VERB
elements-9064	55	8	valuable	valuable	ADJ
elements-9064	55	9	insight	insight	NOUN
elements-9064	55	10	into	into	ADP
elements-9064	55	11	the	the	DET
elements-9064	55	12	barriers	barrier	NOUN
elements-9064	55	13	to	to	ADP
elements-9064	55	14	cross	cross	ADJ
elements-9064	55	15	-	-	ADJ
elements-9064	55	16	species	species	ADJ
elements-9064	55	17	transmission	transmission	NOUN
elements-9064	55	18	of	of	ADP
elements-9064	55	19	lentiviruses	lentiviruse	NOUN
elements-9064	55	20	,	,	PUNCT
elements-9064	55	21	and	and	CCONJ
elements-9064	55	22	offers	offer	VERB
elements-9064	55	23	further	further	ADJ
elements-9064	55	24	support	support	NOUN
elements-9064	55	25	to	to	ADP
elements-9064	55	26	the	the	DET
elements-9064	55	27	idea	idea	NOUN
elements-9064	55	28	of	of	ADP
elements-9064	55	29	an	an	DET
elements-9064	55	30	evolutionary	evolutionary	ADJ
elements-9064	55	31	“	"	PUNCT
elements-9064	55	32	arms	arm	NOUN
elements-9064	55	33	race	race	NOUN
elements-9064	55	34	”	"	PUNCT
elements-9064	55	35	between	between	ADP
elements-9064	55	36	restriction	restriction	NOUN
elements-9064	55	37	factors	factor	NOUN
elements-9064	55	38	and	and	CCONJ
elements-9064	55	39	their	their	PRON
elements-9064	55	40	viral	viral	ADJ
elements-9064	55	41	antagonists	antagonist	NOUN
elements-9064	55	42	.	.	PUNCT
elements-9064	56	1	materials	material	NOUN
elements-9064	56	2	and	and	CCONJ
elements-9064	56	3	methods	method	NOUN
elements-9064	56	4	cell	cell	NOUN
elements-9064	56	5	lines	line	NOUN
elements-9064	56	6	hek293	hek293	PROPN
elements-9064	56	7	t	t	PROPN
elements-9064	56	8	cells	cell	NOUN
elements-9064	56	9	were	be	AUX
elements-9064	56	10	maintained	maintain	VERB
elements-9064	56	11	in	in	ADP
elements-9064	56	12	dulbecco	dulbecco	NOUN
elements-9064	56	13	’s	’s	PART
elements-9064	56	14	modified	modify	VERB
elements-9064	56	15	eagles	eagle	NOUN
elements-9064	56	16	medium	medium	ADJ
elements-9064	56	17	(	(	PUNCT
elements-9064	56	18	dmem	dmem	ADJ
elements-9064	56	19	)	)	PUNCT
elements-9064	56	20	containing	contain	VERB
elements-9064	56	21	10	10	NUM
elements-9064	56	22	%	%	NOUN
elements-9064	56	23	fbs	fbs	PROPN
elements-9064	56	24	,	,	PUNCT
elements-9064	56	25	1	1	NUM
elements-9064	56	26	%	%	NOUN
elements-9064	56	27	l	l	NOUN
elements-9064	56	28	-	-	NOUN
elements-9064	56	29	glutamine	glutamine	NOUN
elements-9064	56	30	,	,	PUNCT
elements-9064	56	31	1	1	NUM
elements-9064	56	32	%	%	NOUN
elements-9064	56	33	penicillin	penicillin	NOUN
elements-9064	56	34	streptomycin	streptomycin	PROPN
elements-9064	56	35	mixture	mixture	NOUN
elements-9064	56	36	,	,	PUNCT
elements-9064	56	37	and	and	CCONJ
elements-9064	56	38	2.5	2.5	NUM
elements-9064	56	39	%	%	NOUN
elements-9064	56	40	hepes	hepe	NOUN
elements-9064	56	41	.	.	PUNCT
elements-9064	57	1	reverse	reverse	VERB
elements-9064	57	2	transcriptase	transcriptase	NOUN
elements-9064	57	3	pcr	pcr	PROPN
elements-9064	57	4	(	(	PUNCT
elements-9064	57	5	rt	rt	NOUN
elements-9064	57	6	-	-	PUNCT
elements-9064	57	7	pcr	pcr	NOUN
elements-9064	57	8	)	)	PUNCT
elements-9064	57	9	and	and	CCONJ
elements-9064	57	10	cloning	clone	VERB
elements-9064	57	11	rt	rt	ADJ
elements-9064	57	12	-	-	PUNCT
elements-9064	57	13	pcr	pcr	ADJ
elements-9064	57	14	reactions	reaction	NOUN
elements-9064	57	15	were	be	AUX
elements-9064	57	16	performed	perform	VERB
elements-9064	57	17	on	on	ADP
elements-9064	57	18	rna	rna	NOUN
elements-9064	57	19	samples	sample	NOUN
elements-9064	57	20	(	(	PUNCT
elements-9064	57	21	extracted	extract	VERB
elements-9064	57	22	previously	previously	ADV
elements-9064	57	23	at	at	ADP
elements-9064	57	24	the	the	DET
elements-9064	57	25	new	new	PROPN
elements-9064	57	26	england	england	PROPN
elements-9064	57	27	primate	primate	PROPN
elements-9064	57	28	research	research	NOUN
elements-9064	57	29	center	center	NOUN
elements-9064	57	30	)	)	PUNCT
elements-9064	57	31	using	use	VERB
elements-9064	57	32	the	the	DET
elements-9064	57	33	invitrogen	invitrogen	PROPN
elements-9064	57	34	(	(	PUNCT
elements-9064	57	35	carlsbad	carlsbad	PROPN
elements-9064	57	36	,	,	PUNCT
elements-9064	57	37	ca	ca	PROPN
elements-9064	57	38	)	)	PUNCT
elements-9064	57	39	superscript	superscript	PROPN
elements-9064	57	40	®	®	NOUN
elements-9064	57	41	iii	iii	NUM
elements-9064	57	42	one	one	NUM
elements-9064	57	43	-	-	PUNCT
elements-9064	57	44	step	step	NOUN
elements-9064	57	45	rt	rt	ADJ
elements-9064	57	46	-	-	PUNCT
elements-9064	57	47	pcr	pcr	ADJ
elements-9064	57	48	system	system	NOUN
elements-9064	57	49	or	or	CCONJ
elements-9064	57	50	the	the	DET
elements-9064	57	51	qiagen	qiagen	NOUN
elements-9064	57	52	(	(	PUNCT
elements-9064	57	53	hilden	hilden	PROPN
elements-9064	57	54	,	,	PUNCT
elements-9064	57	55	germany	germany	PROPN
elements-9064	57	56	)	)	PUNCT
elements-9064	57	57	onestep	onestep	NOUN
elements-9064	57	58	rt	rt	PROPN
elements-9064	57	59	-	-	PUNCT
elements-9064	57	60	pcr	pcr	PROPN
elements-9064	57	61	kit	kit	NOUN
elements-9064	57	62	according	accord	VERB
elements-9064	57	63	their	their	PRON
elements-9064	57	64	associated	associated	ADJ
elements-9064	57	65	protocols	protocol	NOUN
elements-9064	57	66	.	.	PUNCT
elements-9064	58	1	gateway	gateway	NOUN
elements-9064	58	2	cloning	cloning	NOUN
elements-9064	58	3	forward	forward	ADV
elements-9064	58	4	and	and	CCONJ
elements-9064	58	5	reverse	reverse	ADJ
elements-9064	58	6	primers	primer	NOUN
elements-9064	58	7	were	be	AUX
elements-9064	58	8	used	use	VERB
elements-9064	58	9	(	(	PUNCT
elements-9064	58	10	table	table	NOUN
elements-9064	58	11	1	1	NUM
elements-9064	58	12	)	)	PUNCT
elements-9064	58	13	.	.	PUNCT
elements-9064	59	1	products	product	NOUN
elements-9064	59	2	were	be	AUX
elements-9064	59	3	identified	identify	VERB
elements-9064	59	4	via	via	ADP
elements-9064	59	5	gel	gel	NOUN
elements-9064	59	6	electrophoresis	electrophoresis	NOUN
elements-9064	59	7	and	and	CCONJ
elements-9064	59	8	purified	purified	ADJ
elements-9064	59	9	using	use	VERB
elements-9064	59	10	qiagen	qiagen	NOUN
elements-9064	59	11	qiaquick	qiaquick	NOUN
elements-9064	59	12	gel	gel	NOUN
elements-9064	59	13	extraction	extraction	NOUN
elements-9064	59	14	kit	kit	NOUN
elements-9064	59	15	according	accord	VERB
elements-9064	59	16	to	to	ADP
elements-9064	59	17	the	the	DET
elements-9064	59	18	protocols	protocol	NOUN
elements-9064	59	19	specified	specify	VERB
elements-9064	59	20	in	in	ADP
elements-9064	59	21	the	the	DET
elements-9064	59	22	kit	kit	NOUN
elements-9064	59	23	.	.	PUNCT
elements-9064	60	1	purified	purified	ADJ
elements-9064	60	2	dna	dna	PROPN
elements-9064	60	3	samples	sample	NOUN
elements-9064	60	4	were	be	AUX
elements-9064	60	5	cloned	clone	VERB
elements-9064	60	6	using	use	VERB
elements-9064	60	7	the	the	DET
elements-9064	60	8	invitrogen	invitrogen	PROPN
elements-9064	60	9	gateway	gateway	NOUN
elements-9064	60	10	®	®	NOUN
elements-9064	60	11	cloning	cloning	NOUN
elements-9064	60	12	system	system	NOUN
elements-9064	60	13	and	and	CCONJ
elements-9064	60	14	its	its	PRON
elements-9064	60	15	associated	associated	ADJ
elements-9064	60	16	protocols	protocol	NOUN
elements-9064	60	17	.	.	PUNCT
elements-9064	61	1	purified	purified	ADJ
elements-9064	61	2	pcr	pcr	ADJ
elements-9064	61	3	samples	sample	NOUN
elements-9064	61	4	were	be	AUX
elements-9064	61	5	cloned	clone	VERB
elements-9064	61	6	into	into	ADP
elements-9064	61	7	invitrogen	invitrogen	PROPN
elements-9064	61	8	pentr	pentr	PROPN
elements-9064	61	9	®	®	PROPN
elements-9064	61	10	/d	/d	NOUN
elements-9064	61	11	-	-	PUNCT
elements-9064	61	12	topo	topo	NOUN
elements-9064	61	13	plasmids	plasmid	NOUN
elements-9064	61	14	.	.	PUNCT
elements-9064	62	1	the	the	DET
elements-9064	62	2	clones	clone	NOUN
elements-9064	62	3	were	be	AUX
elements-9064	62	4	transformed	transform	VERB
elements-9064	62	5	into	into	ADP
elements-9064	62	6	invitrogen	invitrogen	PROPN
elements-9064	62	7	one	one	NUM
elements-9064	62	8	shot	shot	NOUN
elements-9064	62	9	®	®	NOUN
elements-9064	62	10	stbl3tm	stbl3tm	NOUN
elements-9064	62	11	chemically	chemically	ADV
elements-9064	62	12	competent	competent	ADJ
elements-9064	62	13	e.coli	e.coli	NOUN
elements-9064	62	14	and	and	CCONJ
elements-9064	62	15	transformants	transformant	NOUN
elements-9064	62	16	were	be	AUX
elements-9064	62	17	selected	select	VERB
elements-9064	62	18	for	for	ADP
elements-9064	62	19	via	via	ADP
elements-9064	62	20	kanamycin	kanamycin	PROPN
elements-9064	62	21	selective	selective	ADJ
elements-9064	62	22	plating	plating	NOUN
elements-9064	62	23	.	.	PUNCT
elements-9064	63	1	plasmid	plasmid	ADJ
elements-9064	63	2	dna	dna	PROPN
elements-9064	63	3	was	be	AUX
elements-9064	63	4	isolated	isolate	VERB
elements-9064	63	5	using	use	VERB
elements-9064	63	6	the	the	DET
elements-9064	63	7	qiagen	qiagen	NOUN
elements-9064	63	8	qiaprep	qiaprep	NOUN
elements-9064	63	9	spin	spin	VERB
elements-9064	63	10	miniprep	miniprep	NOUN
elements-9064	63	11	kit	kit	NOUN
elements-9064	63	12	and	and	CCONJ
elements-9064	63	13	its	its	PRON
elements-9064	63	14	associated	associated	ADJ
elements-9064	63	15	protocols	protocol	NOUN
elements-9064	63	16	,	,	PUNCT
elements-9064	63	17	and	and	CCONJ
elements-9064	63	18	then	then	ADV
elements-9064	63	19	sent	send	VERB
elements-9064	63	20	to	to	ADP
elements-9064	63	21	eton	eton	PROPN
elements-9064	63	22	bioscience	bioscience	PROPN
elements-9064	63	23	(	(	PUNCT
elements-9064	63	24	charlestown	charlestown	PROPN
elements-9064	63	25	,	,	PUNCT
elements-9064	63	26	ma	ma	PROPN
elements-9064	63	27	)	)	PUNCT
elements-9064	63	28	for	for	ADP
elements-9064	63	29	sequencing	sequence	VERB
elements-9064	63	30	to	to	PART
elements-9064	63	31	confirm	confirm	VERB
elements-9064	63	32	the	the	DET
elements-9064	63	33	identity	identity	NOUN
elements-9064	63	34	of	of	ADP
elements-9064	63	35	a3f	a3f	ADJ
elements-9064	63	36	sequence	sequence	NOUN
elements-9064	63	37	.	.	PUNCT
elements-9064	64	1	selected	select	VERB
elements-9064	64	2	clones	clone	NOUN
elements-9064	64	3	were	be	AUX
elements-9064	64	4	then	then	ADV
elements-9064	64	5	subcloned	subclone	VERB
elements-9064	64	6	into	into	ADP
elements-9064	64	7	invitrogen	invitrogen	PROPN
elements-9064	64	8	pcdna3.2tm	pcdna3.2tm	PROPN
elements-9064	64	9	/	/	SYM
elements-9064	64	10	v5	v5	NOUN
elements-9064	64	11	-	-	PUNCT
elements-9064	64	12	dest	dest	ADJ
elements-9064	64	13	plasmids	plasmid	NOUN
elements-9064	64	14	(	(	PUNCT
elements-9064	64	15	figure	figure	NOUN
elements-9064	64	16	4	4	NUM
elements-9064	64	17	)	)	PUNCT
elements-9064	64	18	.	.	PUNCT
elements-9064	65	1	the	the	DET
elements-9064	65	2	clones	clone	NOUN
elements-9064	65	3	were	be	AUX
elements-9064	65	4	transformed	transform	VERB
elements-9064	65	5	into	into	ADP
elements-9064	65	6	invitrogen	invitrogen	PROPN
elements-9064	65	7	one	one	NUM
elements-9064	65	8	shot	shot	NOUN
elements-9064	65	9	®	®	NOUN
elements-9064	65	10	stbl3tm	stbl3tm	VERB
elements-9064	65	11	competent	competent	ADJ
elements-9064	65	12	e.coli	e.coli	NOUN
elements-9064	65	13	and	and	CCONJ
elements-9064	65	14	transformants	transformant	NOUN
elements-9064	65	15	were	be	AUX
elements-9064	65	16	selected	select	VERB
elements-9064	65	17	for	for	ADP
elements-9064	65	18	via	via	ADP
elements-9064	65	19	ampicillin	ampicillin	PROPN
elements-9064	65	20	selective	selective	ADJ
elements-9064	65	21	plating	plating	NOUN
elements-9064	65	22	.	.	PUNCT
elements-9064	66	1	plasmid	plasmid	ADJ
elements-9064	66	2	dna	dna	PROPN
elements-9064	66	3	was	be	AUX
elements-9064	66	4	isolated	isolate	VERB
elements-9064	66	5	as	as	ADP
elements-9064	66	6	before	before	ADV
elements-9064	66	7	,	,	PUNCT
elements-9064	66	8	and	and	CCONJ
elements-9064	66	9	clones	clone	NOUN
elements-9064	66	10	were	be	AUX
elements-9064	66	11	sequenced	sequence	VERB
elements-9064	66	12	again	again	ADV
elements-9064	66	13	to	to	PART
elements-9064	66	14	confirm	confirm	VERB
elements-9064	66	15	a3f	a3f	ADJ
elements-9064	66	16	insertion	insertion	NOUN
elements-9064	66	17	.	.	PUNCT
elements-9064	67	1	dn	dn	ADJ
elements-9064	67	2	/	/	SYM
elements-9064	67	3	ds	ds	ADJ
elements-9064	67	4	analysis	analysis	NOUN
elements-9064	67	5	a3f	a3f	ADJ
elements-9064	67	6	sequences	sequence	NOUN
elements-9064	67	7	from	from	ADP
elements-9064	67	8	rhesus	rhesus	NOUN
elements-9064	67	9	macaques	macaque	NOUN
elements-9064	67	10	and	and	CCONJ
elements-9064	67	11	other	other	ADJ
elements-9064	67	12	primates	primate	NOUN
elements-9064	67	13	obtained	obtain	VERB
elements-9064	67	14	from	from	ADP
elements-9064	67	15	our	our	PRON
elements-9064	67	16	own	own	ADJ
elements-9064	67	17	clones	clone	NOUN
elements-9064	67	18	and	and	CCONJ
elements-9064	67	19	from	from	ADP
elements-9064	67	20	the	the	DET
elements-9064	67	21	ncbi	ncbi	PROPN
elements-9064	67	22	database	database	NOUN
elements-9064	67	23	(	(	PUNCT
elements-9064	67	24	see	see	VERB
elements-9064	67	25	appendix	appendix	NOUN
elements-9064	67	26	for	for	ADP
elements-9064	67	27	sequences	sequence	NOUN
elements-9064	67	28	)	)	PUNCT
elements-9064	67	29	were	be	AUX
elements-9064	67	30	trimmed	trim	VERB
elements-9064	67	31	and	and	CCONJ
elements-9064	67	32	aligned	align	VERB
elements-9064	67	33	using	use	VERB
elements-9064	67	34	the	the	DET
elements-9064	67	35	multiple	multiple	ADJ
elements-9064	67	36	align	align	ADJ
elements-9064	67	37	function	function	NOUN
elements-9064	67	38	in	in	ADP
elements-9064	67	39	geneious	geneious	ADJ
elements-9064	67	40	6.1.8	6.1.8	NUM
elements-9064	67	41	software	software	NOUN
elements-9064	67	42	(	(	PUNCT
elements-9064	67	43	created	create	VERB
elements-9064	67	44	by	by	ADP
elements-9064	67	45	biomatters	biomatter	NOUN
elements-9064	67	46	,	,	PUNCT
elements-9064	67	47	available	available	ADJ
elements-9064	67	48	at	at	ADP
elements-9064	67	49	http://	http://	PROPN
elements-9064	67	50	www.geneious.com	www.geneious.com	PROPN
elements-9064	67	51	)	)	PUNCT
elements-9064	67	52	.	.	PUNCT
elements-9064	68	1	the	the	DET
elements-9064	68	2	trimmed	trim	VERB
elements-9064	68	3	sequences	sequence	NOUN
elements-9064	68	4	were	be	AUX
elements-9064	68	5	edited	edit	VERB
elements-9064	68	6	such	such	ADJ
elements-9064	68	7	that	that	DET
elements-9064	68	8	extraneous	extraneous	ADJ
elements-9064	68	9	sequence	sequence	NOUN
elements-9064	68	10	before	before	ADP
elements-9064	68	11	or	or	CCONJ
elements-9064	68	12	after	after	SCONJ
elements-9064	68	13	the	the	DET
elements-9064	68	14	a3f	a3f	PROPN
elements-9064	68	15	open	open	ADJ
elements-9064	68	16	reading	reading	NOUN
elements-9064	68	17	frame	frame	NOUN
elements-9064	68	18	was	be	AUX
elements-9064	68	19	deleted	delete	VERB
elements-9064	68	20	.	.	PUNCT
elements-9064	69	1	the	the	DET
elements-9064	69	2	sequences	sequence	NOUN
elements-9064	69	3	were	be	AUX
elements-9064	69	4	up52	up52	PROPN
elements-9064	69	5	elements	element	NOUN
elements-9064	69	6	:	:	PUNCT
elements-9064	69	7	:	:	PUNCT
elements-9064	69	8	fall	fall	VERB
elements-9064	69	9	2015	2015	NUM
elements-9064	69	10	loaded	load	VERB
elements-9064	69	11	to	to	ADP
elements-9064	69	12	datamonkey	datamonkey	PROPN
elements-9064	69	13	,	,	PUNCT
elements-9064	69	14	a	a	DET
elements-9064	69	15	public	public	ADJ
elements-9064	69	16	server	server	NOUN
elements-9064	69	17	for	for	ADP
elements-9064	69	18	comparative	comparative	ADJ
elements-9064	69	19	analysis	analysis	NOUN
elements-9064	69	20	of	of	ADP
elements-9064	69	21	sequence	sequence	NOUN
elements-9064	69	22	alignments.44,45,46	alignments.44,45,46	PRON
elements-9064	69	23	all	all	DET
elements-9064	69	24	three	three	NUM
elements-9064	69	25	available	available	ADJ
elements-9064	69	26	models	model	NOUN
elements-9064	69	27	for	for	ADP
elements-9064	69	28	dn	dn	ADJ
elements-9064	69	29	/	/	SYM
elements-9064	69	30	ds	ds	ADJ
elements-9064	69	31	analysis	analysis	NOUN
elements-9064	69	32	(	(	PUNCT
elements-9064	69	33	slac	slac	PROPN
elements-9064	69	34	,	,	PUNCT
elements-9064	69	35	fel	fel	PROPN
elements-9064	69	36	,	,	PUNCT
elements-9064	69	37	rel	rel	NOUN
elements-9064	69	38	)	)	PUNCT
elements-9064	69	39	were	be	AUX
elements-9064	69	40	run	run	VERB
elements-9064	69	41	for	for	ADP
elements-9064	69	42	the	the	DET
elements-9064	69	43	relatively	relatively	ADV
elements-9064	69	44	small	small	ADJ
elements-9064	69	45	data	datum	NOUN
elements-9064	69	46	set	set	VERB
elements-9064	69	47	of	of	ADP
elements-9064	69	48	15	15	NUM
elements-9064	69	49	sequences	sequence	NOUN
elements-9064	69	50	.	.	PUNCT
elements-9064	70	1	as	as	SCONJ
elements-9064	70	2	suggested	suggest	VERB
elements-9064	70	3	by	by	ADP
elements-9064	70	4	prior	prior	ADJ
elements-9064	70	5	research	research	NOUN
elements-9064	70	6	,	,	PUNCT
elements-9064	70	7	the	the	DET
elements-9064	70	8	slac	slac	PROPN
elements-9064	70	9	and	and	CCONJ
elements-9064	70	10	fel	fel	PROPN
elements-9064	70	11	models	model	NOUN
elements-9064	70	12	were	be	AUX
elements-9064	70	13	run	run	VERB
elements-9064	70	14	with	with	ADP
elements-9064	70	15	p	p	NOUN
elements-9064	70	16	values	value	NOUN
elements-9064	70	17	of	of	ADP
elements-9064	70	18	0.25	0.25	NUM
elements-9064	70	19	,	,	PUNCT
elements-9064	70	20	while	while	SCONJ
elements-9064	70	21	the	the	DET
elements-9064	70	22	rel	rel	NOUN
elements-9064	70	23	model	model	NOUN
elements-9064	70	24	was	be	AUX
elements-9064	70	25	run	run	VERB
elements-9064	70	26	with	with	ADP
elements-9064	70	27	the	the	DET
elements-9064	70	28	datamonkey	datamonkey	NOUN
elements-9064	70	29	-	-	PUNCT
elements-9064	70	30	suggested	suggest	VERB
elements-9064	70	31	bayes	bayes	PROPN
elements-9064	70	32	factor	factor	NOUN
elements-9064	70	33	of	of	ADP
elements-9064	70	34	50.47	50.47	NUM
elements-9064	70	35	genotyping	genotype	VERB
elements-9064	70	36	pcr	pcr	NOUN
elements-9064	70	37	was	be	AUX
elements-9064	70	38	performed	perform	VERB
elements-9064	70	39	on	on	ADP
elements-9064	70	40	rhesus	rhesus	NOUN
elements-9064	70	41	macaque	macaque	ADJ
elements-9064	70	42	genomic	genomic	NOUN
elements-9064	70	43	dna	dna	NOUN
elements-9064	70	44	samples	sample	NOUN
elements-9064	70	45	obtained	obtain	VERB
elements-9064	70	46	from	from	ADP
elements-9064	70	47	multiple	multiple	ADJ
elements-9064	70	48	us	us	PROPN
elements-9064	70	49	primate	primate	NOUN
elements-9064	70	50	research	research	NOUN
elements-9064	70	51	centers	center	NOUN
elements-9064	70	52	using	use	VERB
elements-9064	70	53	invitrogen	invitrogen	PROPN
elements-9064	70	54	platinum	platinum	NOUN
elements-9064	70	55	®	®	NOUN
elements-9064	70	56	pcr	pcr	ADJ
elements-9064	70	57	supermix	supermix	NOUN
elements-9064	70	58	and	and	CCONJ
elements-9064	70	59	its	its	PRON
elements-9064	70	60	associated	associated	ADJ
elements-9064	70	61	protocols	protocol	NOUN
elements-9064	70	62	.	.	PUNCT
elements-9064	71	1	the	the	DET
elements-9064	71	2	primers	primer	NOUN
elements-9064	71	3	used	use	VERB
elements-9064	71	4	were	be	AUX
elements-9064	71	5	genotyping	genotype	VERB
elements-9064	71	6	forward	forward	ADV
elements-9064	71	7	and	and	CCONJ
elements-9064	71	8	reverse	reverse	VERB
elements-9064	71	9	(	(	PUNCT
elements-9064	71	10	table	table	NOUN
elements-9064	71	11	1	1	NUM
elements-9064	71	12	)	)	PUNCT
elements-9064	71	13	.	.	PUNCT
elements-9064	72	1	the	the	DET
elements-9064	72	2	pcr	pcr	PROPN
elements-9064	72	3	products	product	NOUN
elements-9064	72	4	were	be	AUX
elements-9064	72	5	visualized	visualize	VERB
elements-9064	72	6	via	via	ADP
elements-9064	72	7	gel	gel	NOUN
elements-9064	72	8	electrophoresis	electrophoresis	NOUN
elements-9064	72	9	,	,	PUNCT
elements-9064	72	10	purified	purify	VERB
elements-9064	72	11	using	use	VERB
elements-9064	72	12	the	the	DET
elements-9064	72	13	qiagen	qiagen	NOUN
elements-9064	72	14	qiaquick	qiaquick	NOUN
elements-9064	72	15	gel	gel	NOUN
elements-9064	72	16	extraction	extraction	NOUN
elements-9064	72	17	kit	kit	NOUN
elements-9064	72	18	according	accord	VERB
elements-9064	72	19	to	to	ADP
elements-9064	72	20	its	its	PRON
elements-9064	72	21	associated	associated	ADJ
elements-9064	72	22	protocols	protocol	NOUN
elements-9064	72	23	,	,	PUNCT
elements-9064	72	24	and	and	CCONJ
elements-9064	72	25	sent	send	VERB
elements-9064	72	26	to	to	ADP
elements-9064	72	27	eton	eton	PROPN
elements-9064	72	28	bioscience	bioscience	NOUN
elements-9064	72	29	for	for	ADP
elements-9064	72	30	sequencing	sequence	VERB
elements-9064	72	31	.	.	PUNCT
elements-9064	73	1	the	the	DET
elements-9064	73	2	sequence	sequence	NOUN
elements-9064	73	3	chromatograms	chromatogram	NOUN
elements-9064	73	4	were	be	AUX
elements-9064	73	5	aligned	align	VERB
elements-9064	73	6	using	use	VERB
elements-9064	73	7	geneious	geneious	ADJ
elements-9064	73	8	6.1.8	6.1.8	NUM
elements-9064	73	9	software	software	NOUN
elements-9064	73	10	and	and	CCONJ
elements-9064	73	11	examined	examine	VERB
elements-9064	73	12	for	for	ADP
elements-9064	73	13	the	the	DET
elements-9064	73	14	presence	presence	NOUN
elements-9064	73	15	of	of	ADP
elements-9064	73	16	the	the	DET
elements-9064	73	17	skeh	skeh	ADJ
elements-9064	73	18	/	/	SYM
elements-9064	73	19	fqqy	fqqy	ADJ
elements-9064	73	20	variants	variant	NOUN
elements-9064	73	21	.	.	PUNCT
elements-9064	74	1	mutagenesis	mutagenesis	NOUN
elements-9064	74	2	around	around	ADP
elements-9064	74	3	-	-	PUNCT
elements-9064	74	4	the	the	DET
elements-9064	74	5	-	-	PUNCT
elements-9064	74	6	horn	horn	NOUN
elements-9064	74	7	pcr	pcr	NOUN
elements-9064	74	8	was	be	AUX
elements-9064	74	9	used	use	VERB
elements-9064	74	10	to	to	PART
elements-9064	74	11	mutate	mutate	VERB
elements-9064	74	12	amino	amino	ADJ
elements-9064	74	13	acids	acid	NOUN
elements-9064	74	14	60	60	NUM
elements-9064	74	15	,	,	PUNCT
elements-9064	74	16	61	61	NUM
elements-9064	74	17	,	,	PUNCT
elements-9064	74	18	63	63	NUM
elements-9064	74	19	,	,	PUNCT
elements-9064	74	20	and	and	CCONJ
elements-9064	74	21	64	64	NUM
elements-9064	74	22	from	from	ADP
elements-9064	74	23	the	the	DET
elements-9064	74	24	fqqy	fqqy	ADJ
elements-9064	74	25	variant	variant	NOUN
elements-9064	74	26	to	to	ADP
elements-9064	74	27	the	the	DET
elements-9064	74	28	skeh	skeh	ADJ
elements-9064	74	29	variant	variant	NOUN
elements-9064	74	30	(	(	PUNCT
elements-9064	74	31	or	or	CCONJ
elements-9064	74	32	vice	vice	NOUN
elements-9064	74	33	versa	versa	ADV
elements-9064	74	34	)	)	PUNCT
elements-9064	74	35	in	in	ADP
elements-9064	74	36	select	select	ADJ
elements-9064	74	37	rha3f	rha3f	ADJ
elements-9064	74	38	clones	clone	NOUN
elements-9064	74	39	.	.	PUNCT
elements-9064	75	1	pcr	pcr	PROPN
elements-9064	75	2	was	be	AUX
elements-9064	75	3	performed	perform	VERB
elements-9064	75	4	using	use	VERB
elements-9064	75	5	thermo	thermo	NOUN
elements-9064	75	6	scientific	scientific	NOUN
elements-9064	75	7	(	(	PUNCT
elements-9064	75	8	waltham	waltham	PROPN
elements-9064	75	9	,	,	PUNCT
elements-9064	75	10	ma	ma	PROPN
elements-9064	75	11	)	)	PUNCT
elements-9064	75	12	phusion	phusion	PROPN
elements-9064	75	13	flash	flash	PROPN
elements-9064	75	14	high	high	ADJ
elements-9064	75	15	fidelity	fidelity	PROPN
elements-9064	75	16	pcr	pcr	PROPN
elements-9064	75	17	master	master	NOUN
elements-9064	75	18	mix	mix	NOUN
elements-9064	75	19	and	and	CCONJ
elements-9064	75	20	its	its	PRON
elements-9064	75	21	associated	associated	ADJ
elements-9064	75	22	protocols	protocol	NOUN
elements-9064	75	23	,	,	PUNCT
elements-9064	75	24	and	and	CCONJ
elements-9064	75	25	the	the	DET
elements-9064	75	26	patch	patch	NOUN
elements-9064	75	27	mutant	mutant	NOUN
elements-9064	75	28	forward	forward	ADV
elements-9064	75	29	and	and	CCONJ
elements-9064	75	30	reverse	reverse	ADJ
elements-9064	75	31	primers	primer	NOUN
elements-9064	75	32	were	be	AUX
elements-9064	75	33	used	use	VERB
elements-9064	75	34	.	.	PUNCT
elements-9064	76	1	pcr	pcr	ADJ
elements-9064	76	2	products	product	NOUN
elements-9064	76	3	were	be	AUX
elements-9064	76	4	digested	digest	VERB
elements-9064	76	5	with	with	ADP
elements-9064	76	6	10u	10u	NOUN
elements-9064	76	7	of	of	ADP
elements-9064	76	8	dpni	dpni	PROPN
elements-9064	76	9	(	(	PUNCT
elements-9064	76	10	new	new	PROPN
elements-9064	76	11	england	england	PROPN
elements-9064	76	12	biolabs	biolabs	PROPN
elements-9064	76	13	;	;	PUNCT
elements-9064	76	14	ipswich	ipswich	PROPN
elements-9064	76	15	,	,	PUNCT
elements-9064	76	16	ma	ma	PROPN
elements-9064	76	17	)	)	PUNCT
elements-9064	76	18	and	and	CCONJ
elements-9064	76	19	purified	purified	ADJ
elements-9064	76	20	using	use	VERB
elements-9064	76	21	the	the	DET
elements-9064	76	22	qiagen	qiagen	NOUN
elements-9064	76	23	qiaquick	qiaquick	NOUN
elements-9064	76	24	pcr	pcr	PROPN
elements-9064	76	25	purification	purification	NOUN
elements-9064	76	26	kit	kit	NOUN
elements-9064	76	27	and	and	CCONJ
elements-9064	76	28	its	its	PRON
elements-9064	76	29	associated	associated	ADJ
elements-9064	76	30	protocols	protocol	NOUN
elements-9064	76	31	.	.	PUNCT
elements-9064	77	1	ligation	ligation	NOUN
elements-9064	77	2	was	be	AUX
elements-9064	77	3	performed	perform	VERB
elements-9064	77	4	using	use	VERB
elements-9064	77	5	the	the	DET
elements-9064	77	6	promega	promega	PROPN
elements-9064	77	7	(	(	PUNCT
elements-9064	77	8	madison	madison	PROPN
elements-9064	77	9	,	,	PUNCT
elements-9064	77	10	wi	wi	PROPN
elements-9064	77	11	)	)	PUNCT
elements-9064	77	12	ligafasttm	ligafasttm	VERB
elements-9064	77	13	rapid	rapid	ADJ
elements-9064	77	14	ligation	ligation	NOUN
elements-9064	77	15	system	system	NOUN
elements-9064	77	16	and	and	CCONJ
elements-9064	77	17	its	its	PRON
elements-9064	77	18	associated	associated	ADJ
elements-9064	77	19	protocols	protocol	NOUN
elements-9064	77	20	.	.	PUNCT
elements-9064	78	1	the	the	DET
elements-9064	78	2	clones	clone	NOUN
elements-9064	78	3	were	be	AUX
elements-9064	78	4	transformed	transform	VERB
elements-9064	78	5	into	into	ADP
elements-9064	78	6	invitrogen	invitrogen	PROPN
elements-9064	78	7	one	one	NUM
elements-9064	78	8	shot	shot	NOUN
elements-9064	78	9	®	®	NOUN
elements-9064	78	10	stbl3tm	stbl3tm	VERB
elements-9064	78	11	competent	competent	ADJ
elements-9064	78	12	e.coli	e.coli	NOUN
elements-9064	78	13	,	,	PUNCT
elements-9064	78	14	and	and	CCONJ
elements-9064	78	15	transformants	transformant	NOUN
elements-9064	78	16	were	be	AUX
elements-9064	78	17	selected	select	VERB
elements-9064	78	18	for	for	ADP
elements-9064	78	19	via	via	ADP
elements-9064	78	20	ampicillin	ampicillin	PROPN
elements-9064	78	21	selective	selective	ADJ
elements-9064	78	22	plating	plating	NOUN
elements-9064	78	23	.	.	PUNCT
elements-9064	79	1	plasmid	plasmid	ADJ
elements-9064	79	2	dna	dna	PROPN
elements-9064	79	3	was	be	AUX
elements-9064	79	4	isolated	isolate	VERB
elements-9064	79	5	using	use	VERB
elements-9064	79	6	the	the	DET
elements-9064	79	7	qiagen	qiagen	NOUN
elements-9064	79	8	qiaprep	qiaprep	NOUN
elements-9064	79	9	spin	spin	VERB
elements-9064	79	10	miniprep	miniprep	NOUN
elements-9064	79	11	kit	kit	NOUN
elements-9064	79	12	and	and	CCONJ
elements-9064	79	13	its	its	PRON
elements-9064	79	14	associated	associated	ADJ
elements-9064	79	15	protocols	protocol	NOUN
elements-9064	79	16	,	,	PUNCT
elements-9064	79	17	and	and	CCONJ
elements-9064	79	18	then	then	ADV
elements-9064	79	19	sent	send	VERB
elements-9064	79	20	to	to	ADP
elements-9064	79	21	eton	eton	PROPN
elements-9064	79	22	bioscience	bioscience	NOUN
elements-9064	79	23	for	for	ADP
elements-9064	79	24	sequencing	sequence	VERB
elements-9064	79	25	to	to	PART
elements-9064	79	26	confirm	confirm	VERB
elements-9064	79	27	successful	successful	ADJ
elements-9064	79	28	mutagenesis	mutagenesis	NOUN
elements-9064	79	29	of	of	ADP
elements-9064	79	30	a3f	a3f	PROPN
elements-9064	79	31	.	.	PUNCT
elements-9064	80	1	immunoblotting	immunoblotte	VERB
elements-9064	80	2	plasmids	plasmid	NOUN
elements-9064	80	3	to	to	PART
elements-9064	80	4	be	be	AUX
elements-9064	80	5	used	use	VERB
elements-9064	80	6	in	in	ADP
elements-9064	80	7	cell	cell	NOUN
elements-9064	80	8	culture	culture	NOUN
elements-9064	80	9	were	be	AUX
elements-9064	80	10	prepared	prepare	VERB
elements-9064	80	11	using	use	VERB
elements-9064	80	12	the	the	DET
elements-9064	80	13	invitrogen	invitrogen	PROPN
elements-9064	80	14	purelink	purelink	NOUN
elements-9064	80	15	®	®	NOUN
elements-9064	80	16	hipure	hipure	NOUN
elements-9064	80	17	plasmid	plasmid	NOUN
elements-9064	80	18	maxiprep	maxiprep	NOUN
elements-9064	80	19	kit	kit	NOUN
elements-9064	80	20	and	and	CCONJ
elements-9064	80	21	its	its	PRON
elements-9064	80	22	associated	associated	ADJ
elements-9064	80	23	protocols	protocol	NOUN
elements-9064	80	24	.	.	PUNCT
elements-9064	81	1	hek293	hek293	PROPN
elements-9064	81	2	t	t	PROPN
elements-9064	81	3	cells	cell	NOUN
elements-9064	81	4	were	be	AUX
elements-9064	81	5	seeded	seed	VERB
elements-9064	81	6	in	in	ADP
elements-9064	81	7	6	6	NUM
elements-9064	81	8	-	-	PUNCT
elements-9064	81	9	well	well	NOUN
elements-9064	81	10	plates	plate	NOUN
elements-9064	81	11	at	at	ADP
elements-9064	81	12	a	a	DET
elements-9064	81	13	density	density	NOUN
elements-9064	81	14	of	of	ADP
elements-9064	81	15	800,000	800,000	NUM
elements-9064	81	16	-	-	SYM
elements-9064	81	17	1,000,000	1,000,000	NUM
elements-9064	81	18	cells/	cells/	NUM
elements-9064	81	19	well	well	ADV
elements-9064	81	20	or	or	CCONJ
elements-9064	81	21	12	12	NUM
elements-9064	81	22	-	-	PUNCT
elements-9064	81	23	well	well	NOUN
elements-9064	81	24	plates	plate	NOUN
elements-9064	81	25	at	at	ADP
elements-9064	81	26	a	a	DET
elements-9064	81	27	density	density	NOUN
elements-9064	81	28	of	of	ADP
elements-9064	81	29	200,000	200,000	NUM
elements-9064	81	30	-	-	PUNCT
elements-9064	81	31	400,000	400,000	NUM
elements-9064	81	32	cells	cell	NOUN
elements-9064	81	33	/	/	SYM
elements-9064	82	1	well	well	NOUN
elements-9064	82	2	24	24	NUM
elements-9064	82	3	-	-	SYM
elements-9064	82	4	48	48	NUM
elements-9064	82	5	hours	hour	NOUN
elements-9064	82	6	prior	prior	ADV
elements-9064	82	7	to	to	ADP
elements-9064	82	8	transfection	transfection	NOUN
elements-9064	82	9	.	.	PUNCT
elements-9064	83	1	cells	cell	NOUN
elements-9064	83	2	were	be	AUX
elements-9064	83	3	transfected	transfecte	VERB
elements-9064	83	4	with	with	ADP
elements-9064	83	5	1	1	NUM
elements-9064	83	6	-	-	PUNCT
elements-9064	83	7	3ug	3ug	ADJ
elements-9064	83	8	total	total	ADJ
elements-9064	83	9	dna	dna	NOUN
elements-9064	83	10	using	use	VERB
elements-9064	83	11	genjet	genjet	ADJ
elements-9064	83	12	reagent	reagent	NOUN
elements-9064	83	13	(	(	PUNCT
elements-9064	83	14	signagen	signagen	ADJ
elements-9064	83	15	laboratories	laboratory	NOUN
elements-9064	83	16	;	;	PUNCT
elements-9064	83	17	gaithersburg	gaithersburg	PROPN
elements-9064	83	18	,	,	PUNCT
elements-9064	83	19	md	md	PROPN
elements-9064	83	20	)	)	PUNCT
elements-9064	83	21	and	and	CCONJ
elements-9064	83	22	its	its	PRON
elements-9064	83	23	associated	associated	ADJ
elements-9064	83	24	protocols	protocol	NOUN
elements-9064	83	25	.	.	PUNCT
elements-9064	84	1	cells	cell	NOUN
elements-9064	84	2	were	be	AUX
elements-9064	84	3	harvested	harvest	VERB
elements-9064	84	4	48	48	NUM
elements-9064	84	5	hours	hour	NOUN
elements-9064	84	6	posttransfection	posttransfection	NOUN
elements-9064	84	7	using	use	VERB
elements-9064	84	8	100	100	NUM
elements-9064	84	9	-	-	PUNCT
elements-9064	84	10	200ul	200ul	ADJ
elements-9064	84	11	ip	ip	PRON
elements-9064	84	12	lysis	lysis	NOUN
elements-9064	84	13	buffer	buffer	NOUN
elements-9064	84	14	.	.	PUNCT
elements-9064	85	1	samples	sample	NOUN
elements-9064	85	2	were	be	AUX
elements-9064	85	3	added	add	VERB
elements-9064	85	4	to	to	ADP
elements-9064	85	5	2x	2x	NUM
elements-9064	85	6	laemmli	laemmli	NOUN
elements-9064	85	7	buffer	buffer	NOUN
elements-9064	85	8	and	and	CCONJ
elements-9064	85	9	boiled	boil	VERB
elements-9064	85	10	for	for	ADP
elements-9064	85	11	10	10	NUM
elements-9064	85	12	minutes	minute	NOUN
elements-9064	85	13	.	.	PUNCT
elements-9064	86	1	proteins	protein	NOUN
elements-9064	86	2	were	be	AUX
elements-9064	86	3	separated	separate	VERB
elements-9064	86	4	using	use	VERB
elements-9064	86	5	sds	sds	NOUN
elements-9064	86	6	/	/	SYM
elements-9064	86	7	page	page	NOUN
elements-9064	86	8	and	and	CCONJ
elements-9064	86	9	then	then	ADV
elements-9064	86	10	transferred	transfer	VERB
elements-9064	86	11	to	to	ADP
elements-9064	86	12	pvdf	pvdf	PROPN
elements-9064	86	13	or	or	CCONJ
elements-9064	86	14	nitrocellulose	nitrocellulose	NOUN
elements-9064	86	15	membranes	membrane	NOUN
elements-9064	86	16	via	via	ADP
elements-9064	86	17	bio	bio	PROPN
elements-9064	86	18	-	-	PROPN
elements-9064	86	19	rad	rad	PROPN
elements-9064	86	20	(	(	PUNCT
elements-9064	86	21	hercules	hercules	PROPN
elements-9064	86	22	,	,	PUNCT
elements-9064	86	23	ca	ca	NOUN
elements-9064	86	24	)	)	PUNCT
elements-9064	86	25	mini	mini	NOUN
elements-9064	86	26	trans	trans	PROPN
elements-9064	86	27	-	-	ADJ
elements-9064	86	28	blot	blot	ADJ
elements-9064	86	29	electrophoretic	electrophoretic	ADJ
elements-9064	86	30	transfer	transfer	NOUN
elements-9064	86	31	cell	cell	NOUN
elements-9064	86	32	and	and	CCONJ
elements-9064	86	33	its	its	PRON
elements-9064	86	34	associated	associated	ADJ
elements-9064	86	35	protocols	protocol	NOUN
elements-9064	86	36	.	.	PUNCT
elements-9064	87	1	membranes	membrane	NOUN
elements-9064	87	2	were	be	AUX
elements-9064	87	3	blocked	block	VERB
elements-9064	87	4	overnight	overnight	ADV
elements-9064	87	5	in	in	ADP
elements-9064	87	6	1.25	1.25	NUM
elements-9064	87	7	%	%	NOUN
elements-9064	87	8	milk	milk	NOUN
elements-9064	87	9	,	,	PUNCT
elements-9064	87	10	washed	wash	VERB
elements-9064	87	11	in	in	ADP
elements-9064	87	12	1x	1x	NUM
elements-9064	88	1	pbs0.1	pbs0.1	PROPN
elements-9064	88	2	%	%	NOUN
elements-9064	88	3	tween-20	tween-20	PROPN
elements-9064	88	4	solution	solution	NOUN
elements-9064	88	5	,	,	PUNCT
elements-9064	88	6	and	and	CCONJ
elements-9064	88	7	incubated	incubate	VERB
elements-9064	88	8	for	for	ADP
elements-9064	88	9	1	1	NUM
elements-9064	88	10	hour	hour	NOUN
elements-9064	88	11	in	in	ADP
elements-9064	88	12	antiv5	antiv5	NOUN
elements-9064	88	13	-	-	PUNCT
elements-9064	88	14	hrp	hrp	PROPN
elements-9064	88	15	(	(	PUNCT
elements-9064	88	16	novex	novex	PROPN
elements-9064	88	17	;	;	PUNCT
elements-9064	88	18	carlsbad	carlsbad	PROPN
elements-9064	88	19	,	,	PUNCT
elements-9064	88	20	ca	ca	NOUN
elements-9064	88	21	)	)	PUNCT
elements-9064	88	22	to	to	PART
elements-9064	88	23	probe	probe	VERB
elements-9064	88	24	for	for	ADP
elements-9064	88	25	a3	a3	NOUN
elements-9064	88	26	protein	protein	NOUN
elements-9064	88	27	or	or	CCONJ
elements-9064	88	28	anti	anti	ADJ
elements-9064	88	29	-	-	ADJ
elements-9064	88	30	β	β	ADJ
elements-9064	88	31	-	-	PUNCT
elements-9064	88	32	actin	actin	NOUN
elements-9064	88	33	-	-	PUNCT
elements-9064	88	34	hrp	hrp	NOUN
elements-9064	88	35	antibody	antibody	NOUN
elements-9064	88	36	(	(	PUNCT
elements-9064	88	37	abcam	abcam	PROPN
elements-9064	88	38	;	;	PUNCT
elements-9064	88	39	cambridge	cambridge	PROPN
elements-9064	88	40	,	,	PUNCT
elements-9064	88	41	ma	ma	PROPN
elements-9064	88	42	)	)	PUNCT
elements-9064	88	43	to	to	PART
elements-9064	88	44	probe	probe	VERB
elements-9064	88	45	for	for	ADP
elements-9064	88	46	β	β	NOUN
elements-9064	88	47	-	-	NOUN
elements-9064	88	48	actin	actin	NOUN
elements-9064	88	49	.	.	PUNCT
elements-9064	89	1	alternatively	alternatively	ADV
elements-9064	89	2	,	,	PUNCT
elements-9064	89	3	a	a	DET
elements-9064	89	4	primary	primary	ADJ
elements-9064	89	5	mouse	mouse	NOUN
elements-9064	89	6	monoclonal	monoclonal	NOUN
elements-9064	89	7	anti	anti	ADJ
elements-9064	89	8	-	-	ADJ
elements-9064	89	9	β	β	ADJ
elements-9064	89	10	-	-	PUNCT
elements-9064	89	11	actin	actin	ADJ
elements-9064	89	12	antibody	antibody	NOUN
elements-9064	89	13	(	(	PUNCT
elements-9064	89	14	sigma	sigma	PROPN
elements-9064	89	15	-	-	PUNCT
elements-9064	89	16	aldrich	aldrich	PROPN
elements-9064	89	17	;	;	PUNCT
elements-9064	89	18	st	st	PROPN
elements-9064	89	19	.	.	PROPN
elements-9064	89	20	louis	louis	PROPN
elements-9064	89	21	,	,	PUNCT
elements-9064	89	22	mo	mo	NOUN
elements-9064	89	23	)	)	PUNCT
elements-9064	89	24	and	and	CCONJ
elements-9064	89	25	secondary	secondary	ADJ
elements-9064	89	26	anti	anti	ADJ
elements-9064	89	27	-	-	ADJ
elements-9064	89	28	mouse	mouse	ADJ
elements-9064	89	29	-	-	PUNCT
elements-9064	89	30	hrp	hrp	NOUN
elements-9064	89	31	antibody	antibody	NOUN
elements-9064	89	32	(	(	PUNCT
elements-9064	89	33	thermo	thermo	NOUN
elements-9064	89	34	scientific	scientific	NOUN
elements-9064	89	35	)	)	PUNCT
elements-9064	89	36	were	be	AUX
elements-9064	89	37	used	use	VERB
elements-9064	89	38	to	to	PART
elements-9064	89	39	probe	probe	VERB
elements-9064	89	40	for	for	ADP
elements-9064	89	41	β	β	NOUN
elements-9064	89	42	-	-	NOUN
elements-9064	89	43	actin	actin	NOUN
elements-9064	89	44	.	.	PUNCT
elements-9064	90	1	all	all	DET
elements-9064	90	2	antibodies	antibody	NOUN
elements-9064	90	3	were	be	AUX
elements-9064	90	4	diluted	dilute	VERB
elements-9064	90	5	in	in	ADP
elements-9064	90	6	1.25	1.25	NUM
elements-9064	90	7	%	%	NOUN
elements-9064	90	8	milk	milk	NOUN
elements-9064	90	9	according	accord	VERB
elements-9064	90	10	to	to	ADP
elements-9064	90	11	manufacturer	manufacturer	NOUN
elements-9064	90	12	’s	’s	PART
elements-9064	90	13	specifications	specification	NOUN
elements-9064	90	14	.	.	PUNCT
elements-9064	91	1	after	after	ADP
elements-9064	91	2	washing	wash	VERB
elements-9064	91	3	again	again	ADV
elements-9064	91	4	,	,	PUNCT
elements-9064	91	5	blots	blot	NOUN
elements-9064	91	6	were	be	AUX
elements-9064	91	7	developed	develop	VERB
elements-9064	91	8	using	use	VERB
elements-9064	91	9	either	either	CCONJ
elements-9064	91	10	amersham	amersham	PROPN
elements-9064	91	11	ecl	ecl	PROPN
elements-9064	91	12	prime	prime	ADJ
elements-9064	91	13	western	western	ADJ
elements-9064	91	14	blotting	blot	VERB
elements-9064	91	15	detection	detection	NOUN
elements-9064	91	16	reagent	reagent	NOUN
elements-9064	91	17	(	(	PUNCT
elements-9064	91	18	ge	ge	PROPN
elements-9064	91	19	healthcare	healthcare	PROPN
elements-9064	91	20	life	life	PROPN
elements-9064	91	21	sciences	science	NOUN
elements-9064	91	22	;	;	PUNCT
elements-9064	91	23	little	little	ADJ
elements-9064	91	24	chalfont	chalfont	NOUN
elements-9064	91	25	,	,	PUNCT
elements-9064	91	26	buckinghamshire	buckinghamshire	PROPN
elements-9064	91	27	,	,	PUNCT
elements-9064	91	28	united	united	ADJ
elements-9064	91	29	kingdom	kingdom	PROPN
elements-9064	91	30	)	)	PUNCT
elements-9064	91	31	,	,	PUNCT
elements-9064	91	32	or	or	CCONJ
elements-9064	91	33	thermo	thermo	NOUN
elements-9064	91	34	scientific	scientific	ADJ
elements-9064	91	35	supersignaltm	supersignaltm	NOUN
elements-9064	91	36	west	west	PROPN
elements-9064	91	37	femto	femto	PROPN
elements-9064	91	38	maximum	maximum	ADJ
elements-9064	91	39	sensitivity	sensitivity	NOUN
elements-9064	91	40	substrate	substrate	NOUN
elements-9064	91	41	and	and	CCONJ
elements-9064	91	42	then	then	ADV
elements-9064	91	43	visualized	visualize	VERB
elements-9064	91	44	using	use	VERB
elements-9064	91	45	bio	bio	PROPN
elements-9064	91	46	-	-	ADJ
elements-9064	91	47	rad	rad	PROPN
elements-9064	91	48	chemidoc	chemidoc	PROPN
elements-9064	91	49	mp	mp	PROPN
elements-9064	91	50	gel	gel	NOUN
elements-9064	91	51	imaging	imaging	NOUN
elements-9064	91	52	system	system	NOUN
elements-9064	91	53	.	.	PUNCT
elements-9064	92	1	results	results	AUX
elements-9064	92	2	i.	i.	PROPN
elements-9064	92	3	investigating	investigate	VERB
elements-9064	92	4	diversity	diversity	NOUN
elements-9064	92	5	and	and	CCONJ
elements-9064	92	6	positive	positive	ADJ
elements-9064	92	7	selection	selection	NOUN
elements-9064	92	8	in	in	ADP
elements-9064	92	9	old	old	ADJ
elements-9064	92	10	world	world	NOUN
elements-9064	92	11	primate	primate	NOUN
elements-9064	92	12	a3f	a3f	ADJ
elements-9064	92	13	in	in	ADP
elements-9064	92	14	order	order	NOUN
elements-9064	92	15	to	to	PART
elements-9064	92	16	determine	determine	VERB
elements-9064	92	17	whether	whether	SCONJ
elements-9064	92	18	primate	primate	NOUN
elements-9064	92	19	a3f	a3f	ADJ
elements-9064	92	20	displays	display	VERB
elements-9064	92	21	the	the	DET
elements-9064	92	22	hallmarks	hallmark	NOUN
elements-9064	92	23	of	of	ADP
elements-9064	92	24	a	a	DET
elements-9064	92	25	restriction	restriction	NOUN
elements-9064	92	26	factor	factor	NOUN
elements-9064	92	27	that	that	PRON
elements-9064	92	28	has	have	AUX
elements-9064	92	29	been	be	AUX
elements-9064	92	30	antagonized	antagonize	VERB
elements-9064	92	31	over	over	ADP
elements-9064	92	32	time	time	NOUN
elements-9064	92	33	,	,	PUNCT
elements-9064	92	34	rhesus	rhesus	NOUN
elements-9064	92	35	macaque	macaque	NOUN
elements-9064	92	36	(	(	PUNCT
elements-9064	92	37	macaca	macaca	NOUN
elements-9064	92	38	mulatta	mulatta	PROPN
elements-9064	92	39	)	)	PUNCT
elements-9064	92	40	a3f	a3f	ADJ
elements-9064	92	41	sequences	sequence	NOUN
elements-9064	92	42	were	be	AUX
elements-9064	92	43	first	first	ADV
elements-9064	92	44	investigated	investigate	VERB
elements-9064	92	45	for	for	ADP
elements-9064	92	46	evidence	evidence	NOUN
elements-9064	92	47	of	of	ADP
elements-9064	92	48	polymorphism	polymorphism	NOUN
elements-9064	92	49	.	.	PUNCT
elements-9064	93	1	to	to	PART
elements-9064	93	2	examine	examine	VERB
elements-9064	93	3	polymorphism	polymorphism	NOUN
elements-9064	93	4	within	within	ADP
elements-9064	93	5	species	specie	NOUN
elements-9064	93	6	,	,	PUNCT
elements-9064	93	7	rt	rt	PROPN
elements-9064	93	8	-	-	PUNCT
elements-9064	93	9	pcr	pcr	PROPN
elements-9064	93	10	was	be	AUX
elements-9064	93	11	performed	perform	VERB
elements-9064	93	12	on	on	ADP
elements-9064	93	13	rna	rna	NOUN
elements-9064	93	14	samples	sample	NOUN
elements-9064	93	15	obtained	obtain	VERB
elements-9064	93	16	from	from	ADP
elements-9064	93	17	10	10	NUM
elements-9064	93	18	different	different	ADJ
elements-9064	93	19	rhesus	rhesus	NOUN
elements-9064	93	20	macaques	macaque	NOUN
elements-9064	93	21	.	.	PUNCT
elements-9064	94	1	the	the	DET
elements-9064	94	2	resulting	result	VERB
elements-9064	94	3	dna	dna	NOUN
elements-9064	94	4	was	be	AUX
elements-9064	94	5	cloned	clone	VERB
elements-9064	94	6	and	and	CCONJ
elements-9064	94	7	the	the	DET
elements-9064	94	8	sequences	sequence	NOUN
elements-9064	94	9	were	be	AUX
elements-9064	94	10	examined	examine	VERB
elements-9064	94	11	for	for	ADP
elements-9064	94	12	both	both	CCONJ
elements-9064	94	13	silent	silent	ADJ
elements-9064	94	14	and	and	CCONJ
elements-9064	94	15	non	non	ADJ
elements-9064	94	16	-	-	ADJ
elements-9064	94	17	synonymous	synonymous	ADJ
elements-9064	94	18	polymorphisms	polymorphism	NOUN
elements-9064	94	19	.	.	PUNCT
elements-9064	95	1	the	the	DET
elements-9064	95	2	data	datum	NOUN
elements-9064	95	3	showed	show	VERB
elements-9064	95	4	that	that	SCONJ
elements-9064	95	5	a3f	a3f	PROPN
elements-9064	95	6	is	be	AUX
elements-9064	95	7	a	a	DET
elements-9064	95	8	highly	highly	ADV
elements-9064	95	9	polymorphic	polymorphic	ADJ
elements-9064	95	10	gene	gene	NOUN
elements-9064	95	11	in	in	ADP
elements-9064	95	12	rhesus	rhesus	NOUN
elements-9064	95	13	macaques	macaque	NOUN
elements-9064	95	14	,	,	PUNCT
elements-9064	95	15	and	and	CCONJ
elements-9064	95	16	that	that	SCONJ
elements-9064	95	17	many	many	ADJ
elements-9064	95	18	of	of	ADP
elements-9064	95	19	the	the	DET
elements-9064	95	20	single	single	ADJ
elements-9064	95	21	nucleotide	nucleotide	ADJ
elements-9064	95	22	polymorphisms	polymorphism	NOUN
elements-9064	95	23	result	result	VERB
elements-9064	95	24	in	in	ADP
elements-9064	95	25	amino	amino	NOUN
elements-9064	95	26	acid	acid	NOUN
elements-9064	95	27	changes	change	NOUN
elements-9064	95	28	(	(	PUNCT
elements-9064	95	29	figure	figure	NOUN
elements-9064	95	30	2	2	NUM
elements-9064	95	31	)	)	PUNCT
elements-9064	95	32	.	.	PUNCT
elements-9064	96	1	to	to	PART
elements-9064	96	2	examine	examine	VERB
elements-9064	96	3	inter	inter	ADJ
elements-9064	96	4	-	-	ADJ
elements-9064	96	5	species	species	ADJ
elements-9064	96	6	diversity	diversity	NOUN
elements-9064	96	7	,	,	PUNCT
elements-9064	96	8	rt	rt	PROPN
elements-9064	96	9	-	-	PUNCT
elements-9064	96	10	pcr	pcr	PROPN
elements-9064	96	11	was	be	AUX
elements-9064	96	12	also	also	ADV
elements-9064	96	13	performed	perform	VERB
elements-9064	96	14	on	on	ADP
elements-9064	96	15	multiple	multiple	ADJ
elements-9064	96	16	rna	rna	NOUN
elements-9064	96	17	samples	sample	NOUN
elements-9064	96	18	from	from	ADP
elements-9064	96	19	sooty	sooty	NOUN
elements-9064	96	20	mangabeys	mangabey	NOUN
elements-9064	96	21	(	(	PUNCT
elements-9064	96	22	cercocebus	cercocebus	PROPN
elements-9064	96	23	atys	atys	PROPN
elements-9064	96	24	)	)	PUNCT
elements-9064	96	25	,	,	PUNCT
elements-9064	96	26	crab	crab	NOUN
elements-9064	96	27	-	-	PUNCT
elements-9064	96	28	eating	eat	VERB
elements-9064	96	29	macaques	macaque	NOUN
elements-9064	96	30	(	(	PUNCT
elements-9064	96	31	macaca	macaca	NOUN
elements-9064	96	32	fascicularis	fascicularis	NOUN
elements-9064	96	33	)	)	PUNCT
elements-9064	96	34	,	,	PUNCT
elements-9064	96	35	and	and	CCONJ
elements-9064	96	36	pigtail	pigtail	ADJ
elements-9064	96	37	macaques	macaque	NOUN
elements-9064	96	38	(	(	PUNCT
elements-9064	96	39	macaca	macaca	PROPN
elements-9064	96	40	nemestrina	nemestrina	PROPN
elements-9064	96	41	)	)	PUNCT
elements-9064	96	42	.	.	PUNCT
elements-9064	97	1	a3f	a3f	ADJ
elements-9064	97	2	coding	code	VERB
elements-9064	97	3	sequences	sequence	NOUN
elements-9064	97	4	from	from	ADP
elements-9064	97	5	these	these	DET
elements-9064	97	6	related	relate	VERB
elements-9064	97	7	primates	primate	NOUN
elements-9064	97	8	showed	show	VERB
elements-9064	97	9	divergence	divergence	NOUN
elements-9064	97	10	from	from	ADP
elements-9064	97	11	each	each	DET
elements-9064	97	12	other	other	ADJ
elements-9064	97	13	and	and	CCONJ
elements-9064	97	14	from	from	ADP
elements-9064	97	15	rhesus	rhesus	NOUN
elements-9064	97	16	macaques	macaque	NOUN
elements-9064	97	17	,	,	PUNCT
elements-9064	97	18	53	53	NUM
elements-9064	97	19	a	a	DET
elements-9064	97	20	biological	biological	ADJ
elements-9064	97	21	“	"	PUNCT
elements-9064	97	22	arms	arm	NOUN
elements-9064	97	23	race	race	NOUN
elements-9064	97	24	”	"	PUNCT
elements-9064	97	25	demonstrating	demonstrate	VERB
elements-9064	97	26	that	that	SCONJ
elements-9064	97	27	there	there	PRON
elements-9064	97	28	are	be	VERB
elements-9064	97	29	fixed	fix	VERB
elements-9064	97	30	differences	difference	NOUN
elements-9064	97	31	between	between	ADP
elements-9064	97	32	a3f	a3f	ADJ
elements-9064	97	33	genes	gene	NOUN
elements-9064	97	34	in	in	ADP
elements-9064	97	35	old	old	ADJ
elements-9064	97	36	world	world	NOUN
elements-9064	97	37	primates	primate	NOUN
elements-9064	97	38	(	(	PUNCT
elements-9064	97	39	figure	figure	NOUN
elements-9064	97	40	3	3	NUM
elements-9064	97	41	)	)	PUNCT
elements-9064	97	42	.	.	PUNCT
elements-9064	98	1	after	after	ADP
elements-9064	98	2	establishing	establish	VERB
elements-9064	98	3	that	that	PRON
elements-9064	98	4	a3f	a3f	PROPN
elements-9064	98	5	is	be	AUX
elements-9064	98	6	a	a	DET
elements-9064	98	7	polymorphic	polymorphic	ADJ
elements-9064	98	8	gene	gene	NOUN
elements-9064	98	9	in	in	ADP
elements-9064	98	10	rhesus	rhesus	NOUN
elements-9064	98	11	macaques	macaque	NOUN
elements-9064	98	12	and	and	CCONJ
elements-9064	98	13	that	that	SCONJ
elements-9064	98	14	fixed	fix	VERB
elements-9064	98	15	differences	difference	NOUN
elements-9064	98	16	exist	exist	VERB
elements-9064	98	17	between	between	ADP
elements-9064	98	18	a3fs	a3fs	PUNCT
elements-9064	98	19	of	of	ADP
elements-9064	98	20	related	relate	VERB
elements-9064	98	21	old	old	ADJ
elements-9064	98	22	world	world	NOUN
elements-9064	98	23	primates	primate	NOUN
elements-9064	98	24	,	,	PUNCT
elements-9064	98	25	a	a	DET
elements-9064	98	26	dn	dn	NOUN
elements-9064	98	27	/	/	SYM
elements-9064	98	28	ds	ds	ADJ
elements-9064	98	29	analysis	analysis	NOUN
elements-9064	98	30	was	be	AUX
elements-9064	98	31	performed	perform	VERB
elements-9064	98	32	in	in	ADP
elements-9064	98	33	order	order	NOUN
elements-9064	98	34	to	to	PART
elements-9064	98	35	determine	determine	VERB
elements-9064	98	36	whether	whether	SCONJ
elements-9064	98	37	any	any	DET
elements-9064	98	38	codons	codon	NOUN
elements-9064	98	39	have	have	AUX
elements-9064	98	40	evolved	evolve	VERB
elements-9064	98	41	under	under	ADP
elements-9064	98	42	positive	positive	ADJ
elements-9064	98	43	selection	selection	NOUN
elements-9064	98	44	.	.	PUNCT
elements-9064	99	1	the	the	DET
elements-9064	99	2	species	specie	NOUN
elements-9064	99	3	that	that	PRON
elements-9064	99	4	were	be	AUX
elements-9064	99	5	included	include	VERB
elements-9064	99	6	in	in	ADP
elements-9064	99	7	this	this	DET
elements-9064	99	8	analysis	analysis	NOUN
elements-9064	99	9	were	be	AUX
elements-9064	99	10	rhesus	rhesus	NOUN
elements-9064	99	11	macaques	macaque	NOUN
elements-9064	99	12	,	,	PUNCT
elements-9064	99	13	crab	crab	NOUN
elements-9064	99	14	-	-	PUNCT
elements-9064	99	15	eating	eat	VERB
elements-9064	99	16	macaques	macaque	NOUN
elements-9064	99	17	,	,	PUNCT
elements-9064	99	18	pigtail	pigtail	NOUN
elements-9064	99	19	macaques	macaque	NOUN
elements-9064	99	20	,	,	PUNCT
elements-9064	99	21	sooty	sooty	NOUN
elements-9064	99	22	mangabeys	mangabey	NOUN
elements-9064	99	23	,	,	PUNCT
elements-9064	99	24	african	african	ADJ
elements-9064	99	25	green	green	ADJ
elements-9064	99	26	monkeys	monkey	NOUN
elements-9064	99	27	(	(	PUNCT
elements-9064	99	28	chlorocebus	chlorocebus	NOUN
elements-9064	99	29	sabaeus	sabaeus	NOUN
elements-9064	99	30	)	)	PUNCT
elements-9064	99	31	,	,	PUNCT
elements-9064	99	32	humans	human	NOUN
elements-9064	99	33	(	(	PUNCT
elements-9064	99	34	homo	homo	NOUN
elements-9064	99	35	sapiens	sapien	VERB
elements-9064	99	36	)	)	PUNCT
elements-9064	99	37	,	,	PUNCT
elements-9064	99	38	chimpanzees	chimpanzee	NOUN
elements-9064	99	39	(	(	PUNCT
elements-9064	99	40	pan	pan	NOUN
elements-9064	99	41	troglodytes	troglodyte	NOUN
elements-9064	99	42	)	)	PUNCT
elements-9064	99	43	,	,	PUNCT
elements-9064	99	44	bonobos	bonobos	PROPN
elements-9064	99	45	(	(	PUNCT
elements-9064	99	46	pan	pan	NOUN
elements-9064	99	47	paniscus	paniscus	PROPN
elements-9064	99	48	)	)	PUNCT
elements-9064	99	49	,	,	PUNCT
elements-9064	99	50	and	and	CCONJ
elements-9064	99	51	drills	drill	NOUN
elements-9064	99	52	(	(	PUNCT
elements-9064	99	53	mandrillus	mandrillus	PROPN
elements-9064	99	54	leucophaeus	leucophaeus	NOUN
elements-9064	99	55	)	)	PUNCT
elements-9064	99	56	.	.	PUNCT
elements-9064	100	1	these	these	DET
elements-9064	100	2	sequences	sequence	NOUN
elements-9064	100	3	were	be	AUX
elements-9064	100	4	uploaded	upload	VERB
elements-9064	100	5	to	to	ADP
elements-9064	100	6	datamonkey	datamonkey	PROPN
elements-9064	100	7	,	,	PUNCT
elements-9064	100	8	a	a	DET
elements-9064	100	9	public	public	ADJ
elements-9064	100	10	server	server	NOUN
elements-9064	100	11	for	for	ADP
elements-9064	100	12	comparative	comparative	ADJ
elements-9064	100	13	analysis	analysis	NOUN
elements-9064	100	14	of	of	ADP
elements-9064	100	15	sequence	sequence	NOUN
elements-9064	100	16	alignments	alignment	NOUN
elements-9064	100	17	(	(	PUNCT
elements-9064	100	18	see	see	VERB
elements-9064	100	19	dn	dn	NOUN
elements-9064	100	20	/	/	SYM
elements-9064	100	21	ds	ds	ADJ
elements-9064	100	22	section	section	NOUN
elements-9064	100	23	in	in	ADP
elements-9064	100	24	materials	material	NOUN
elements-9064	100	25	and	and	CCONJ
elements-9064	100	26	methods	method	NOUN
elements-9064	100	27	)	)	PUNCT
elements-9064	100	28	.	.	PUNCT
elements-9064	101	1	11	11	NUM
elements-9064	101	2	codons	codon	NOUN
elements-9064	101	3	were	be	AUX
elements-9064	101	4	found	find	VERB
elements-9064	101	5	to	to	PART
elements-9064	101	6	be	be	AUX
elements-9064	101	7	evolving	evolve	VERB
elements-9064	101	8	under	under	ADP
elements-9064	101	9	positive	positive	ADJ
elements-9064	101	10	selection	selection	NOUN
elements-9064	101	11	.	.	PUNCT
elements-9064	102	1	the	the	DET
elements-9064	102	2	sites	site	NOUN
elements-9064	102	3	were	be	AUX
elements-9064	102	4	mapped	map	VERB
elements-9064	102	5	relative	relative	ADJ
elements-9064	102	6	to	to	ADP
elements-9064	102	7	the	the	DET
elements-9064	102	8	deaminase	deaminase	NOUN
elements-9064	102	9	domains	domain	NOUN
elements-9064	102	10	and	and	CCONJ
elements-9064	102	11	catalytic	catalytic	ADJ
elements-9064	102	12	motifs	motif	NOUN
elements-9064	102	13	in	in	ADP
elements-9064	102	14	a3f	a3f	PROPN
elements-9064	102	15	(	(	PUNCT
elements-9064	102	16	figure	figure	NOUN
elements-9064	102	17	4	4	NUM
elements-9064	102	18	)	)	PUNCT
elements-9064	102	19	,	,	PUNCT
elements-9064	102	20	and	and	CCONJ
elements-9064	102	21	seven	seven	NUM
elements-9064	102	22	sites	site	NOUN
elements-9064	102	23	were	be	AUX
elements-9064	102	24	found	find	VERB
elements-9064	102	25	to	to	PART
elements-9064	102	26	overlap	overlap	VERB
elements-9064	102	27	with	with	ADP
elements-9064	102	28	those	those	PRON
elements-9064	102	29	previously	previously	ADV
elements-9064	102	30	identified	identify	VERB
elements-9064	102	31	to	to	PART
elements-9064	102	32	be	be	AUX
elements-9064	102	33	polymorphic	polymorphic	ADJ
elements-9064	102	34	in	in	ADP
elements-9064	102	35	rhesus	rhesus	NOUN
elements-9064	102	36	macaques	macaque	NOUN
elements-9064	102	37	.	.	PUNCT
elements-9064	103	1	ii	ii	PROPN
elements-9064	103	2	.	.	PUNCT
elements-9064	104	1	a	a	DET
elements-9064	104	2	closer	close	ADJ
elements-9064	104	3	look	look	NOUN
elements-9064	104	4	at	at	ADP
elements-9064	104	5	a	a	DET
elements-9064	104	6	polymorphic	polymorphic	ADJ
elements-9064	104	7	and	and	CCONJ
elements-9064	104	8	positively	positively	ADV
elements-9064	104	9	selected	select	VERB
elements-9064	104	10	site	site	NOUN
elements-9064	104	11	in	in	ADP
elements-9064	104	12	rhesus	rhesus	NOUN
elements-9064	104	13	macaques	macaque	NOUN
elements-9064	104	14	four	four	NUM
elements-9064	104	15	codons	codon	NOUN
elements-9064	104	16	at	at	ADP
elements-9064	104	17	positions	position	NOUN
elements-9064	104	18	60	60	NUM
elements-9064	104	19	,	,	PUNCT
elements-9064	104	20	61	61	NUM
elements-9064	104	21	,	,	PUNCT
elements-9064	104	22	63	63	NUM
elements-9064	104	23	,	,	PUNCT
elements-9064	104	24	and	and	CCONJ
elements-9064	104	25	64	64	NUM
elements-9064	104	26	in	in	ADP
elements-9064	104	27	rhesus	rhesus	NOUN
elements-9064	104	28	macaques	macaque	NOUN
elements-9064	104	29	showed	show	VERB
elements-9064	104	30	evidence	evidence	NOUN
elements-9064	104	31	of	of	ADP
elements-9064	104	32	both	both	DET
elements-9064	104	33	intra	intra	ADJ
elements-9064	104	34	-	-	ADJ
elements-9064	104	35	species	species	ADJ
elements-9064	104	36	variability	variability	NOUN
elements-9064	104	37	and	and	CCONJ
elements-9064	104	38	positive	positive	ADJ
elements-9064	104	39	selection	selection	NOUN
elements-9064	104	40	.	.	PUNCT
elements-9064	105	1	in	in	ADP
elements-9064	105	2	the	the	DET
elements-9064	105	3	rha3f	rha3f	ADJ
elements-9064	105	4	clones	clone	NOUN
elements-9064	105	5	,	,	PUNCT
elements-9064	105	6	these	these	DET
elements-9064	105	7	sites	site	NOUN
elements-9064	105	8	were	be	AUX
elements-9064	105	9	linked	link	VERB
elements-9064	105	10	and	and	CCONJ
elements-9064	105	11	appeared	appear	VERB
elements-9064	105	12	as	as	ADP
elements-9064	105	13	either	either	CCONJ
elements-9064	105	14	60fqpqy64	60fqpqy64	NUM
elements-9064	105	15	(	(	PUNCT
elements-9064	105	16	henceforth	henceforth	ADV
elements-9064	105	17	referred	refer	VERB
elements-9064	105	18	to	to	ADP
elements-9064	105	19	as	as	ADP
elements-9064	105	20	fqqy	fqqy	ADV
elements-9064	105	21	)	)	PUNCT
elements-9064	105	22	or	or	CCONJ
elements-9064	106	1	60skpeh64	60skpeh64	NUM
elements-9064	106	2	(	(	PUNCT
elements-9064	106	3	henceforth	henceforth	ADV
elements-9064	106	4	referred	refer	VERB
elements-9064	106	5	to	to	ADP
elements-9064	106	6	as	as	ADV
elements-9064	106	7	skeh	skeh	ADJ
elements-9064	106	8	)	)	PUNCT
elements-9064	106	9	.	.	PUNCT
elements-9064	107	1	20	20	NUM
elements-9064	107	2	of	of	ADP
elements-9064	107	3	35	35	NUM
elements-9064	107	4	clones	clone	NOUN
elements-9064	107	5	showed	show	VERB
elements-9064	107	6	the	the	DET
elements-9064	107	7	fqqy	fqqy	ADJ
elements-9064	107	8	sequence	sequence	NOUN
elements-9064	107	9	,	,	PUNCT
elements-9064	107	10	while	while	SCONJ
elements-9064	107	11	15	15	NUM
elements-9064	107	12	clones	clone	NOUN
elements-9064	107	13	showed	show	VERB
elements-9064	107	14	the	the	DET
elements-9064	107	15	skeh	skeh	ADJ
elements-9064	107	16	sequence	sequence	NOUN
elements-9064	107	17	.	.	PUNCT
elements-9064	108	1	the	the	DET
elements-9064	108	2	patch	patch	NOUN
elements-9064	108	3	change	change	NOUN
elements-9064	108	4	from	from	ADP
elements-9064	108	5	fqqy	fqqy	ADV
elements-9064	108	6	to	to	PART
elements-9064	108	7	skeh	skeh	ADV
elements-9064	108	8	is	be	AUX
elements-9064	108	9	fairly	fairly	ADV
elements-9064	108	10	significant	significant	ADJ
elements-9064	108	11	at	at	ADP
elements-9064	108	12	the	the	DET
elements-9064	108	13	amino	amino	NOUN
elements-9064	108	14	acid	acid	NOUN
elements-9064	108	15	level	level	NOUN
elements-9064	108	16	:	:	PUNCT
elements-9064	108	17	bulky	bulky	ADJ
elements-9064	108	18	hydrophobic	hydrophobic	NOUN
elements-9064	108	19	phenylalanine	phenylalanine	NOUN
elements-9064	108	20	is	be	AUX
elements-9064	108	21	exchanged	exchange	VERB
elements-9064	108	22	for	for	ADP
elements-9064	108	23	a	a	DET
elements-9064	108	24	small	small	ADJ
elements-9064	108	25	polar	polar	ADJ
elements-9064	108	26	serine	serine	NOUN
elements-9064	108	27	,	,	PUNCT
elements-9064	108	28	polar	polar	ADJ
elements-9064	108	29	uncharged	uncharged	ADJ
elements-9064	108	30	glutamine	glutamine	NOUN
elements-9064	108	31	is	be	AUX
elements-9064	108	32	exchanged	exchange	VERB
elements-9064	108	33	for	for	ADP
elements-9064	108	34	a	a	DET
elements-9064	108	35	positively	positively	ADV
elements-9064	108	36	charged	charge	VERB
elements-9064	108	37	lysine	lysine	NOUN
elements-9064	108	38	and	and	CCONJ
elements-9064	108	39	then	then	ADV
elements-9064	108	40	a	a	DET
elements-9064	108	41	negatively	negatively	ADV
elements-9064	108	42	charged	charge	VERB
elements-9064	108	43	glutamic	glutamic	ADJ
elements-9064	108	44	acid	acid	NOUN
elements-9064	108	45	,	,	PUNCT
elements-9064	108	46	and	and	CCONJ
elements-9064	108	47	hydrophobic	hydrophobic	NOUN
elements-9064	108	48	tyrosine	tyrosine	NOUN
elements-9064	108	49	is	be	AUX
elements-9064	108	50	exchanged	exchange	VERB
elements-9064	108	51	for	for	ADP
elements-9064	108	52	a	a	DET
elements-9064	108	53	positively	positively	ADV
elements-9064	108	54	charged	charge	VERB
elements-9064	108	55	histidine	histidine	NOUN
elements-9064	108	56	.	.	PUNCT
elements-9064	109	1	thus	thus	ADV
elements-9064	109	2	,	,	PUNCT
elements-9064	109	3	the	the	DET
elements-9064	109	4	skeh	skeh	ADJ
elements-9064	109	5	variant	variant	NOUN
elements-9064	109	6	has	have	VERB
elements-9064	109	7	three	three	NUM
elements-9064	109	8	charged	charge	VERB
elements-9064	109	9	amino	amino	NOUN
elements-9064	109	10	acids	acid	NOUN
elements-9064	109	11	,	,	PUNCT
elements-9064	109	12	whereas	whereas	SCONJ
elements-9064	109	13	the	the	DET
elements-9064	109	14	fqqy	fqqy	ADJ
elements-9064	109	15	variant	variant	NOUN
elements-9064	109	16	is	be	AUX
elements-9064	109	17	a	a	DET
elements-9064	109	18	neutral	neutral	ADJ
elements-9064	109	19	surface	surface	NOUN
elements-9064	109	20	.	.	PUNCT
elements-9064	110	1	a	a	DET
elements-9064	110	2	broader	broad	ADJ
elements-9064	110	3	genomic	genomic	ADJ
elements-9064	110	4	survey	survey	NOUN
elements-9064	110	5	was	be	AUX
elements-9064	110	6	done	do	VERB
elements-9064	110	7	in	in	ADP
elements-9064	110	8	order	order	NOUN
elements-9064	110	9	to	to	PART
elements-9064	110	10	better	well	ADV
elements-9064	110	11	understand	understand	VERB
elements-9064	110	12	the	the	DET
elements-9064	110	13	level	level	NOUN
elements-9064	110	14	of	of	ADP
elements-9064	110	15	diversity	diversity	NOUN
elements-9064	110	16	in	in	ADP
elements-9064	110	17	the	the	DET
elements-9064	110	18	patch	patch	NOUN
elements-9064	110	19	.	.	PUNCT
elements-9064	111	1	targeted	target	VERB
elements-9064	111	2	pcr	pcr	NOUN
elements-9064	111	3	was	be	AUX
elements-9064	111	4	used	use	VERB
elements-9064	111	5	to	to	PART
elements-9064	111	6	amplify	amplify	VERB
elements-9064	111	7	an	an	DET
elements-9064	111	8	approximately	approximately	ADV
elements-9064	111	9	680	680	NUM
elements-9064	111	10	base	base	NOUN
elements-9064	111	11	pair	pair	NOUN
elements-9064	111	12	(	(	PUNCT
elements-9064	111	13	bp	bp	PROPN
elements-9064	111	14	)	)	PUNCT
elements-9064	111	15	stretch	stretch	NOUN
elements-9064	111	16	of	of	ADP
elements-9064	111	17	a3f	a3f	PROPN
elements-9064	111	18	from	from	ADP
elements-9064	111	19	genomic	genomic	ADJ
elements-9064	111	20	dna	dna	NOUN
elements-9064	111	21	samples	sample	NOUN
elements-9064	111	22	representing	represent	VERB
elements-9064	111	23	44	44	NUM
elements-9064	111	24	different	different	ADJ
elements-9064	111	25	rhesus	rhesus	NOUN
elements-9064	111	26	macaques	macaque	NOUN
elements-9064	111	27	.	.	PUNCT
elements-9064	112	1	15	15	NUM
elements-9064	112	2	animals	animal	NOUN
elements-9064	112	3	appeared	appear	VERB
elements-9064	112	4	to	to	PART
elements-9064	112	5	be	be	AUX
elements-9064	112	6	heterozygous	heterozygous	ADJ
elements-9064	112	7	fqqy	fqqy	ADV
elements-9064	112	8	/	/	SYM
elements-9064	112	9	skeh	skeh	ADJ
elements-9064	112	10	,	,	PUNCT
elements-9064	112	11	17	17	NUM
elements-9064	112	12	animals	animal	NOUN
elements-9064	112	13	appeared	appear	VERB
elements-9064	112	14	to	to	PART
elements-9064	112	15	be	be	AUX
elements-9064	112	16	homozygous	homozygous	ADJ
elements-9064	112	17	fqqy	fqqy	ADV
elements-9064	112	18	/	/	SYM
elements-9064	112	19	fqqy	fqqy	ADV
elements-9064	112	20	,	,	PUNCT
elements-9064	112	21	and	and	CCONJ
elements-9064	112	22	12	12	NUM
elements-9064	112	23	animals	animal	NOUN
elements-9064	112	24	appeared	appear	VERB
elements-9064	112	25	to	to	PART
elements-9064	112	26	be	be	AUX
elements-9064	112	27	homozygous	homozygous	ADJ
elements-9064	112	28	skeh	skeh	ADV
elements-9064	112	29	/	/	SYM
elements-9064	112	30	skeh	skeh	ADJ
elements-9064	112	31	.	.	PUNCT
elements-9064	113	1	this	this	DET
elements-9064	113	2	frequency	frequency	NOUN
elements-9064	113	3	distribution	distribution	NOUN
elements-9064	113	4	correlated	correlate	VERB
elements-9064	113	5	to	to	ADP
elements-9064	113	6	the	the	DET
elements-9064	113	7	results	result	NOUN
elements-9064	113	8	from	from	ADP
elements-9064	113	9	the	the	DET
elements-9064	113	10	cloned	clone	VERB
elements-9064	113	11	sequences	sequence	NOUN
elements-9064	113	12	.	.	PUNCT
elements-9064	114	1	thus	thus	ADV
elements-9064	114	2	,	,	PUNCT
elements-9064	114	3	it	it	PRON
elements-9064	114	4	is	be	AUX
elements-9064	114	5	reasonable	reasonable	ADJ
elements-9064	114	6	to	to	PART
elements-9064	114	7	conclude	conclude	VERB
elements-9064	114	8	that	that	SCONJ
elements-9064	114	9	this	this	DET
elements-9064	114	10	patch	patch	NOUN
elements-9064	114	11	has	have	AUX
elements-9064	114	12	maintained	maintain	VERB
elements-9064	114	13	a	a	DET
elements-9064	114	14	high	high	ADJ
elements-9064	114	15	level	level	NOUN
elements-9064	114	16	of	of	ADP
elements-9064	114	17	diversity	diversity	NOUN
elements-9064	114	18	within	within	ADP
elements-9064	114	19	rhesus	rhesus	NOUN
elements-9064	114	20	macaques	macaque	NOUN
elements-9064	114	21	,	,	PUNCT
elements-9064	114	22	and	and	CCONJ
elements-9064	114	23	that	that	SCONJ
elements-9064	114	24	this	this	DET
elements-9064	114	25	diversity	diversity	NOUN
elements-9064	114	26	is	be	AUX
elements-9064	114	27	not	not	PART
elements-9064	114	28	unique	unique	ADJ
elements-9064	114	29	to	to	ADP
elements-9064	114	30	a	a	DET
elements-9064	114	31	particular	particular	ADJ
elements-9064	114	32	population	population	NOUN
elements-9064	114	33	of	of	ADP
elements-9064	114	34	animals	animal	NOUN
elements-9064	114	35	or	or	CCONJ
elements-9064	114	36	the	the	DET
elements-9064	114	37	result	result	NOUN
elements-9064	114	38	of	of	ADP
elements-9064	114	39	a	a	DET
elements-9064	114	40	small	small	ADJ
elements-9064	114	41	data	datum	NOUN
elements-9064	114	42	set	set	VERB
elements-9064	114	43	.	.	PUNCT
elements-9064	115	1	iii	iii	X
elements-9064	115	2	.	.	PUNCT
elements-9064	116	1	the	the	DET
elements-9064	116	2	functional	functional	ADJ
elements-9064	116	3	significance	significance	NOUN
elements-9064	116	4	of	of	ADP
elements-9064	116	5	diversity	diversity	NOUN
elements-9064	116	6	after	after	ADP
elements-9064	116	7	demonstrating	demonstrate	VERB
elements-9064	116	8	that	that	SCONJ
elements-9064	116	9	there	there	PRON
elements-9064	116	10	is	be	VERB
elements-9064	116	11	a	a	DET
elements-9064	116	12	high	high	ADJ
elements-9064	116	13	level	level	NOUN
elements-9064	116	14	of	of	ADP
elements-9064	116	15	diversity	diversity	NOUN
elements-9064	116	16	in	in	ADP
elements-9064	116	17	primate	primate	NOUN
elements-9064	116	18	a3f	a3f	ADJ
elements-9064	116	19	and	and	CCONJ
elements-9064	116	20	that	that	SCONJ
elements-9064	116	21	some	some	DET
elements-9064	116	22	sites	site	NOUN
elements-9064	116	23	in	in	ADP
elements-9064	116	24	the	the	DET
elements-9064	116	25	gene	gene	NOUN
elements-9064	116	26	have	have	AUX
elements-9064	116	27	evolved	evolve	VERB
elements-9064	116	28	under	under	ADP
elements-9064	116	29	positive	positive	ADJ
elements-9064	116	30	selection	selection	NOUN
elements-9064	116	31	,	,	PUNCT
elements-9064	116	32	experiments	experiment	NOUN
elements-9064	116	33	were	be	AUX
elements-9064	116	34	done	do	VERB
elements-9064	116	35	to	to	PART
elements-9064	116	36	determine	determine	VERB
elements-9064	116	37	whether	whether	SCONJ
elements-9064	116	38	the	the	DET
elements-9064	116	39	different	different	ADJ
elements-9064	116	40	a3f	a3f	ADJ
elements-9064	116	41	alleles	allele	NOUN
elements-9064	116	42	displayed	display	VERB
elements-9064	116	43	differential	differential	ADJ
elements-9064	116	44	susceptibilities	susceptibility	NOUN
elements-9064	116	45	to	to	ADP
elements-9064	116	46	vifs	vif	NOUN
elements-9064	116	47	of	of	ADP
elements-9064	116	48	various	various	ADJ
elements-9064	116	49	siv	siv	NOUN
elements-9064	116	50	strains	strain	NOUN
elements-9064	116	51	.	.	PUNCT
elements-9064	117	1	first	first	ADJ
elements-9064	117	2	,	,	PUNCT
elements-9064	117	3	a3f	a3f	ADJ
elements-9064	117	4	clones	clone	NOUN
elements-9064	117	5	from	from	ADP
elements-9064	117	6	rhesus	rhesus	NOUN
elements-9064	117	7	macaques	macaque	NOUN
elements-9064	117	8	,	,	PUNCT
elements-9064	117	9	crab	crab	NOUN
elements-9064	117	10	-	-	PUNCT
elements-9064	117	11	eating	eat	VERB
elements-9064	117	12	macaques	macaque	NOUN
elements-9064	117	13	,	,	PUNCT
elements-9064	117	14	sooty	sooty	NOUN
elements-9064	117	15	mangabeys	mangabey	NOUN
elements-9064	117	16	,	,	PUNCT
elements-9064	117	17	and	and	CCONJ
elements-9064	117	18	pigtail	pigtail	ADJ
elements-9064	117	19	macaques	macaque	NOUN
elements-9064	117	20	were	be	AUX
elements-9064	117	21	tested	test	VERB
elements-9064	117	22	for	for	ADP
elements-9064	117	23	expression	expression	NOUN
elements-9064	117	24	in	in	ADP
elements-9064	117	25	hek293	hek293	PROPN
elements-9064	117	26	t	t	NOUN
elements-9064	117	27	cells	cell	NOUN
elements-9064	117	28	.	.	PUNCT
elements-9064	118	1	of	of	ADP
elements-9064	118	2	the	the	DET
elements-9064	118	3	17	17	NUM
elements-9064	118	4	clones	clone	NOUN
elements-9064	118	5	tested	test	VERB
elements-9064	118	6	,	,	PUNCT
elements-9064	118	7	11	11	NUM
elements-9064	118	8	were	be	AUX
elements-9064	118	9	found	find	VERB
elements-9064	118	10	to	to	PART
elements-9064	118	11	express	express	VERB
elements-9064	118	12	,	,	PUNCT
elements-9064	118	13	as	as	SCONJ
elements-9064	118	14	visualized	visualize	VERB
elements-9064	118	15	via	via	ADP
elements-9064	118	16	western	western	ADJ
elements-9064	118	17	blot	blot	NOUN
elements-9064	118	18	(	(	PUNCT
elements-9064	118	19	figure	figure	NOUN
elements-9064	118	20	5	5	NUM
elements-9064	118	21	)	)	PUNCT
elements-9064	118	22	.	.	PUNCT
elements-9064	119	1	they	they	PRON
elements-9064	119	2	expressed	express	VERB
elements-9064	119	3	at	at	ADP
elements-9064	119	4	variable	variable	ADJ
elements-9064	119	5	levels	level	NOUN
elements-9064	119	6	,	,	PUNCT
elements-9064	119	7	and	and	CCONJ
elements-9064	119	8	only	only	ADV
elements-9064	119	9	a	a	DET
elements-9064	119	10	subset	subset	NOUN
elements-9064	119	11	of	of	ADP
elements-9064	119	12	clones	clone	NOUN
elements-9064	119	13	that	that	PRON
elements-9064	119	14	represented	represent	VERB
elements-9064	119	15	diverse	diverse	ADJ
elements-9064	119	16	sequences	sequence	NOUN
elements-9064	119	17	and	and	CCONJ
elements-9064	119	18	were	be	AUX
elements-9064	119	19	wellexpressed	wellexpresse	VERB
elements-9064	119	20	were	be	AUX
elements-9064	119	21	chosen	choose	VERB
elements-9064	119	22	for	for	ADP
elements-9064	119	23	further	further	ADJ
elements-9064	119	24	examination	examination	NOUN
elements-9064	119	25	.	.	PUNCT
elements-9064	120	1	in	in	ADP
elements-9064	120	2	addition	addition	NOUN
elements-9064	120	3	to	to	ADP
elements-9064	120	4	these	these	DET
elements-9064	120	5	clones	clone	NOUN
elements-9064	120	6	representing	represent	VERB
elements-9064	120	7	naturally	naturally	ADV
elements-9064	120	8	occurring	occur	VERB
elements-9064	120	9	rha3fs	rha3fs	NOUN
elements-9064	120	10	,	,	PUNCT
elements-9064	120	11	three	three	NUM
elements-9064	120	12	point	point	NOUN
elements-9064	120	13	mutants	mutant	NOUN
elements-9064	120	14	were	be	AUX
elements-9064	120	15	made	make	VERB
elements-9064	120	16	by	by	ADP
elements-9064	120	17	exchanging	exchange	VERB
elements-9064	120	18	the	the	DET
elements-9064	120	19	fqqy	fqqy	ADJ
elements-9064	120	20	and	and	CCONJ
elements-9064	120	21	skeh	skeh	ADJ
elements-9064	120	22	patches	patch	NOUN
elements-9064	120	23	by	by	ADP
elements-9064	120	24	site	site	NOUN
elements-9064	120	25	-	-	PUNCT
elements-9064	120	26	directed	direct	VERB
elements-9064	120	27	mutagenesis	mutagenesis	NOUN
elements-9064	120	28	.	.	PUNCT
elements-9064	121	1	the	the	DET
elements-9064	121	2	resulting	result	VERB
elements-9064	121	3	clones	clone	NOUN
elements-9064	121	4	contained	contain	VERB
elements-9064	121	5	identical	identical	ADJ
elements-9064	121	6	sequence	sequence	NOUN
elements-9064	121	7	to	to	ADP
elements-9064	121	8	their	their	PRON
elements-9064	121	9	parent	parent	NOUN
elements-9064	121	10	rha3f	rha3f	ADJ
elements-9064	121	11	clone	clone	NOUN
elements-9064	121	12	except	except	SCONJ
elements-9064	121	13	for	for	ADP
elements-9064	121	14	the	the	DET
elements-9064	121	15	four	four	NUM
elements-9064	121	16	nucleotides	nucleotide	NOUN
elements-9064	121	17	that	that	PRON
elements-9064	121	18	are	be	AUX
elements-9064	121	19	responsible	responsible	ADJ
elements-9064	121	20	for	for	ADP
elements-9064	121	21	the	the	DET
elements-9064	121	22	amino	amino	NOUN
elements-9064	121	23	acid	acid	NOUN
elements-9064	121	24	changes	change	NOUN
elements-9064	121	25	at	at	ADP
elements-9064	121	26	this	this	DET
elements-9064	121	27	patch	patch	NOUN
elements-9064	121	28	.	.	PUNCT
elements-9064	122	1	these	these	DET
elements-9064	122	2	point	point	NOUN
elements-9064	122	3	mutants	mutant	NOUN
elements-9064	122	4	were	be	AUX
elements-9064	122	5	also	also	ADV
elements-9064	122	6	tested	test	VERB
elements-9064	122	7	for	for	ADP
elements-9064	122	8	expression	expression	NOUN
elements-9064	122	9	in	in	ADP
elements-9064	122	10	hek293	hek293	PROPN
elements-9064	122	11	t	t	NOUN
elements-9064	122	12	cells	cell	NOUN
elements-9064	122	13	,	,	PUNCT
elements-9064	122	14	and	and	CCONJ
elements-9064	122	15	two	two	NUM
elements-9064	122	16	of	of	ADP
elements-9064	122	17	the	the	DET
elements-9064	122	18	three	three	NUM
elements-9064	122	19	clones	clone	NOUN
elements-9064	122	20	tested	test	VERB
elements-9064	122	21	were	be	AUX
elements-9064	122	22	found	find	VERB
elements-9064	122	23	to	to	PART
elements-9064	122	24	be	be	AUX
elements-9064	122	25	highly	highly	ADV
elements-9064	122	26	expressed	express	VERB
elements-9064	122	27	as	as	SCONJ
elements-9064	122	28	detected	detect	VERB
elements-9064	122	29	via	via	ADP
elements-9064	122	30	western	western	ADJ
elements-9064	122	31	blot	blot	NOUN
elements-9064	122	32	(	(	PUNCT
elements-9064	122	33	figure	figure	NOUN
elements-9064	122	34	5	5	NUM
elements-9064	122	35	)	)	PUNCT
elements-9064	122	36	.	.	PUNCT
elements-9064	123	1	in	in	ADP
elements-9064	123	2	order	order	NOUN
elements-9064	123	3	to	to	PART
elements-9064	123	4	determine	determine	VERB
elements-9064	123	5	whether	whether	SCONJ
elements-9064	123	6	the	the	DET
elements-9064	123	7	rha3f	rha3f	ADJ
elements-9064	123	8	variation	variation	NOUN
elements-9064	123	9	confers	confer	NOUN
elements-9064	123	10	differential	differential	VERB
elements-9064	123	11	resistance	resistance	NOUN
elements-9064	123	12	to	to	ADP
elements-9064	123	13	vif	vif	PROPN
elements-9064	123	14	-	-	PUNCT
elements-9064	123	15	mediated	mediate	VERB
elements-9064	123	16	degradation	degradation	NOUN
elements-9064	123	17	,	,	PUNCT
elements-9064	123	18	hek293	hek293	PROPN
elements-9064	123	19	t	t	NOUN
elements-9064	123	20	cells	cell	NOUN
elements-9064	123	21	were	be	AUX
elements-9064	123	22	simultaneously	simultaneously	ADV
elements-9064	123	23	transfected	transfecte	VERB
elements-9064	123	24	with	with	ADP
elements-9064	123	25	a3f	a3f	ADJ
elements-9064	123	26	expression	expression	NOUN
elements-9064	123	27	constructs	construct	NOUN
elements-9064	123	28	and	and	CCONJ
elements-9064	123	29	vif	vif	NOUN
elements-9064	123	30	expression	expression	NOUN
elements-9064	123	31	constructs	construct	NOUN
elements-9064	123	32	containing	contain	VERB
elements-9064	123	33	the	the	DET
elements-9064	123	34	vif	vif	NOUN
elements-9064	123	35	coding	code	VERB
elements-9064	123	36	sequences	sequence	NOUN
elements-9064	123	37	of	of	ADP
elements-9064	123	38	different	different	ADJ
elements-9064	123	39	siv	siv	NOUN
elements-9064	123	40	strains	strain	NOUN
elements-9064	123	41	.	.	PUNCT
elements-9064	124	1	the	the	DET
elements-9064	124	2	expression	expression	NOUN
elements-9064	124	3	of	of	ADP
elements-9064	124	4	a3f	a3f	PROPN
elements-9064	124	5	in	in	ADP
elements-9064	124	6	the	the	DET
elements-9064	124	7	presence	presence	NOUN
elements-9064	124	8	of	of	ADP
elements-9064	124	9	these	these	DET
elements-9064	124	10	vif	vif	NOUN
elements-9064	124	11	challenges	challenge	NOUN
elements-9064	124	12	was	be	AUX
elements-9064	124	13	then	then	ADV
elements-9064	124	14	detected	detect	VERB
elements-9064	124	15	via	via	ADP
elements-9064	124	16	western	western	ADJ
elements-9064	124	17	blot	blot	NOUN
elements-9064	124	18	and	and	CCONJ
elements-9064	124	19	compared	compare	VERB
elements-9064	124	20	between	between	ADP
elements-9064	124	21	the	the	DET
elements-9064	124	22	different	different	ADJ
elements-9064	124	23	clones	clone	NOUN
elements-9064	124	24	as	as	ADP
elements-9064	124	25	an	an	DET
elements-9064	124	26	indication	indication	NOUN
elements-9064	124	27	of	of	ADP
elements-9064	124	28	susceptibility	susceptibility	NOUN
elements-9064	124	29	to	to	ADP
elements-9064	124	30	vif	vif	NOUN
elements-9064	124	31	-	-	PUNCT
elements-9064	124	32	mediated	mediate	VERB
elements-9064	124	33	degradation	degradation	NOUN
elements-9064	124	34	.	.	PUNCT
elements-9064	125	1	two	two	NUM
elements-9064	125	2	rha3	rha3	PROPN
elements-9064	125	3	g	g	NOUN
elements-9064	125	4	expression	expression	NOUN
elements-9064	125	5	constructs	construct	NOUN
elements-9064	125	6	were	be	AUX
elements-9064	125	7	also	also	ADV
elements-9064	125	8	included	include	VERB
elements-9064	125	9	as	as	ADP
elements-9064	125	10	controls	control	NOUN
elements-9064	125	11	because	because	SCONJ
elements-9064	125	12	their	their	PRON
elements-9064	125	13	phenotypes	phenotype	NOUN
elements-9064	125	14	against	against	ADP
elements-9064	125	15	these	these	DET
elements-9064	125	16	vifs	vif	NOUN
elements-9064	125	17	have	have	AUX
elements-9064	125	18	been	be	AUX
elements-9064	125	19	published	publish	VERB
elements-9064	125	20	previously.48	previously.48	ADV
elements-9064	125	21	a	a	DET
elements-9064	125	22	representative	representative	ADJ
elements-9064	125	23	blot	blot	NOUN
elements-9064	125	24	is	be	AUX
elements-9064	125	25	shown	show	VERB
elements-9064	125	26	in	in	ADP
elements-9064	125	27	figure	figure	NOUN
elements-9064	125	28	6	6	NUM
elements-9064	125	29	,	,	PUNCT
elements-9064	125	30	and	and	CCONJ
elements-9064	125	31	it	it	PRON
elements-9064	125	32	reveals	reveal	VERB
elements-9064	125	33	three	three	NUM
elements-9064	125	34	interesting	interesting	ADJ
elements-9064	125	35	observations	observation	NOUN
elements-9064	125	36	.	.	PUNCT
elements-9064	126	1	first	first	ADV
elements-9064	126	2	,	,	PUNCT
elements-9064	126	3	multiple	multiple	ADJ
elements-9064	126	4	rha3fs	rha3fs	NOUN
elements-9064	126	5	displayed	display	VERB
elements-9064	126	6	resistance	resistance	NOUN
elements-9064	126	7	to	to	ADP
elements-9064	126	8	the	the	DET
elements-9064	126	9	vif	vif	NOUN
elements-9064	126	10	derived	derive	VERB
elements-9064	126	11	from	from	ADP
elements-9064	126	12	rhesus	rhesus	NOUN
elements-9064	126	13	macaque	macaque	ADV
elements-9064	126	14	-	-	PUNCT
elements-9064	126	15	adapted	adapt	VERB
elements-9064	126	16	sivmac239	sivmac239	PROPN
elements-9064	126	17	.	.	PUNCT
elements-9064	127	1	second	second	ADJ
elements-9064	127	2	,	,	PUNCT
elements-9064	127	3	nearly	nearly	ADV
elements-9064	127	4	all	all	PRON
elements-9064	127	5	of	of	ADP
elements-9064	127	6	the	the	DET
elements-9064	127	7	rha3fs	rha3fs	NOUN
elements-9064	127	8	were	be	AUX
elements-9064	127	9	degraded	degrade	VERB
elements-9064	127	10	by	by	ADP
elements-9064	127	11	a	a	DET
elements-9064	127	12	sivsm	sivsm	NOUN
elements-9064	127	13	vif	vif	NOUN
elements-9064	127	14	and	and	CCONJ
elements-9064	127	15	by	by	ADP
elements-9064	127	16	vif	vif	NOUN
elements-9064	127	17	from	from	ADP
elements-9064	127	18	the	the	DET
elements-9064	127	19	stump	stump	NOUN
elements-9064	127	20	-	-	PUNCT
elements-9064	127	21	tailed	tail	VERB
elements-9064	127	22	macaque	macaque	ADJ
elements-9064	127	23	siv	siv	NOUN
elements-9064	127	24	strain	strain	NOUN
elements-9064	127	25	(	(	PUNCT
elements-9064	127	26	sivstm	sivstm	NOUN
elements-9064	127	27	)	)	PUNCT
elements-9064	127	28	.	.	PUNCT
elements-9064	128	1	these	these	PRON
elements-9064	128	2	are	be	AUX
elements-9064	128	3	54	54	NUM
elements-9064	128	4	elements	element	NOUN
elements-9064	128	5	:	:	PUNCT
elements-9064	128	6	:	:	PUNCT
elements-9064	128	7	fall	fall	VERB
elements-9064	128	8	2015	2015	NUM
elements-9064	128	9	somewhat	somewhat	ADV
elements-9064	128	10	surprising	surprising	ADJ
elements-9064	128	11	results	result	NOUN
elements-9064	128	12	,	,	PUNCT
elements-9064	128	13	considering	consider	VERB
elements-9064	128	14	that	that	SCONJ
elements-9064	128	15	the	the	DET
elements-9064	128	16	a3f	a3f	PROPN
elements-9064	128	17	-	-	PUNCT
elements-9064	128	18	vif	vif	NOUN
elements-9064	128	19	interaction	interaction	NOUN
elements-9064	128	20	tends	tend	VERB
elements-9064	128	21	to	to	PART
elements-9064	128	22	be	be	AUX
elements-9064	128	23	species	specie	NOUN
elements-9064	128	24	-	-	PUNCT
elements-9064	128	25	specific	specific	ADJ
elements-9064	128	26	.	.	PUNCT
elements-9064	129	1	viral	viral	ADJ
elements-9064	129	2	antagonist	antagonist	NOUN
elements-9064	129	3	proteins	protein	NOUN
elements-9064	129	4	are	be	AUX
elements-9064	129	5	generally	generally	ADV
elements-9064	129	6	well	well	ADV
elements-9064	129	7	-	-	PUNCT
elements-9064	129	8	adapted	adapt	VERB
elements-9064	129	9	to	to	ADP
elements-9064	129	10	the	the	DET
elements-9064	129	11	restriction	restriction	NOUN
elements-9064	129	12	factors	factor	NOUN
elements-9064	129	13	of	of	ADP
elements-9064	129	14	their	their	PRON
elements-9064	129	15	hosts	host	NOUN
elements-9064	129	16	,	,	PUNCT
elements-9064	129	17	so	so	SCONJ
elements-9064	129	18	one	one	PRON
elements-9064	129	19	would	would	AUX
elements-9064	129	20	expect	expect	VERB
elements-9064	129	21	vif	vif	NOUN
elements-9064	129	22	from	from	ADP
elements-9064	129	23	rhesus	rhesus	NOUN
elements-9064	129	24	macaque	macaque	ADV
elements-9064	129	25	-	-	PUNCT
elements-9064	129	26	adapted	adapt	VERB
elements-9064	129	27	sivmac	sivmac	NOUN
elements-9064	129	28	to	to	PART
elements-9064	129	29	degrade	degrade	VERB
elements-9064	129	30	the	the	DET
elements-9064	129	31	rha3fs	rha3fs	PROPN
elements-9064	129	32	and	and	CCONJ
elements-9064	129	33	vifs	vif	NOUN
elements-9064	129	34	from	from	ADP
elements-9064	129	35	related	related	ADJ
elements-9064	129	36	sivs	sivs	NOUN
elements-9064	129	37	to	to	PART
elements-9064	129	38	not	not	PART
elements-9064	129	39	be	be	AUX
elements-9064	129	40	as	as	ADV
elements-9064	129	41	effective	effective	ADJ
elements-9064	129	42	.	.	PUNCT
elements-9064	130	1	however	however	ADV
elements-9064	130	2	,	,	PUNCT
elements-9064	130	3	this	this	PRON
elements-9064	130	4	was	be	AUX
elements-9064	130	5	not	not	PART
elements-9064	130	6	the	the	DET
elements-9064	130	7	case	case	NOUN
elements-9064	130	8	;	;	PUNCT
elements-9064	130	9	sivmac	sivmac	PROPN
elements-9064	130	10	vif	vif	PROPN
elements-9064	130	11	did	do	AUX
elements-9064	130	12	not	not	PART
elements-9064	130	13	degrade	degrade	VERB
elements-9064	130	14	rha3fs	rha3fs	PROPN
elements-9064	130	15	,	,	PUNCT
elements-9064	130	16	while	while	SCONJ
elements-9064	130	17	vifs	vif	NOUN
elements-9064	130	18	from	from	ADP
elements-9064	130	19	related	related	ADJ
elements-9064	130	20	sivsm	sivsm	NOUN
elements-9064	130	21	and	and	CCONJ
elements-9064	130	22	sivstm	sivstm	NOUN
elements-9064	130	23	did	do	VERB
elements-9064	130	24	.	.	PUNCT
elements-9064	131	1	finally	finally	ADV
elements-9064	131	2	,	,	PUNCT
elements-9064	131	3	the	the	DET
elements-9064	131	4	fqqy	fqqy	ADJ
elements-9064	131	5	/	/	SYM
elements-9064	131	6	skeh	skeh	ADV
elements-9064	131	7	patch	patch	NOUN
elements-9064	131	8	genotype	genotype	NOUN
elements-9064	131	9	did	do	AUX
elements-9064	131	10	not	not	PART
elements-9064	131	11	affect	affect	VERB
elements-9064	131	12	sensitivity	sensitivity	NOUN
elements-9064	131	13	to	to	ADP
elements-9064	131	14	any	any	PRON
elements-9064	131	15	of	of	ADP
elements-9064	131	16	the	the	DET
elements-9064	131	17	vifs	vif	NOUN
elements-9064	131	18	tested	test	VERB
elements-9064	131	19	.	.	PUNCT
elements-9064	132	1	discussion	discussion	NOUN
elements-9064	132	2	investigations	investigation	NOUN
elements-9064	132	3	into	into	ADP
elements-9064	132	4	the	the	DET
elements-9064	132	5	diversity	diversity	NOUN
elements-9064	132	6	of	of	ADP
elements-9064	132	7	primate	primate	NOUN
elements-9064	132	8	a3f	a3f	PROPN
elements-9064	132	9	revealed	reveal	VERB
elements-9064	132	10	that	that	SCONJ
elements-9064	132	11	the	the	DET
elements-9064	132	12	gene	gene	NOUN
elements-9064	132	13	displays	display	VERB
elements-9064	132	14	the	the	DET
elements-9064	132	15	hallmarks	hallmark	NOUN
elements-9064	132	16	of	of	ADP
elements-9064	132	17	a	a	DET
elements-9064	132	18	restriction	restriction	NOUN
elements-9064	132	19	factor	factor	NOUN
elements-9064	132	20	that	that	PRON
elements-9064	132	21	has	have	AUX
elements-9064	132	22	been	be	AUX
elements-9064	132	23	subject	subject	ADJ
elements-9064	132	24	to	to	ADP
elements-9064	132	25	positive	positive	ADJ
elements-9064	132	26	selective	selective	ADJ
elements-9064	132	27	pressure	pressure	NOUN
elements-9064	132	28	by	by	ADP
elements-9064	132	29	viral	viral	ADJ
elements-9064	132	30	antagonists	antagonist	NOUN
elements-9064	132	31	over	over	ADP
elements-9064	132	32	evolutionary	evolutionary	ADJ
elements-9064	132	33	time	time	NOUN
elements-9064	132	34	.	.	PUNCT
elements-9064	133	1	a3f	a3f	ADJ
elements-9064	133	2	is	be	AUX
elements-9064	133	3	a	a	DET
elements-9064	133	4	highly	highly	ADV
elements-9064	133	5	polymorphic	polymorphic	ADJ
elements-9064	133	6	gene	gene	NOUN
elements-9064	133	7	within	within	ADP
elements-9064	133	8	rhesus	rhesus	NOUN
elements-9064	133	9	macaques	macaque	NOUN
elements-9064	133	10	,	,	PUNCT
elements-9064	133	11	and	and	CCONJ
elements-9064	133	12	many	many	ADJ
elements-9064	133	13	singlenucleotide	singlenucleotide	ADJ
elements-9064	133	14	polymorphisms	polymorphism	NOUN
elements-9064	133	15	lead	lead	VERB
elements-9064	133	16	to	to	ADP
elements-9064	133	17	significant	significant	ADJ
elements-9064	133	18	amino	amino	NOUN
elements-9064	133	19	acid	acid	NOUN
elements-9064	133	20	changes	change	NOUN
elements-9064	133	21	.	.	PUNCT
elements-9064	134	1	charged	charge	VERB
elements-9064	134	2	residues	residue	NOUN
elements-9064	134	3	are	be	AUX
elements-9064	134	4	often	often	ADV
elements-9064	134	5	implicated	implicate	VERB
elements-9064	134	6	in	in	ADP
elements-9064	134	7	proteinprotein	proteinprotein	ADJ
elements-9064	134	8	interactions	interaction	NOUN
elements-9064	134	9	,	,	PUNCT
elements-9064	134	10	and	and	CCONJ
elements-9064	134	11	therefore	therefore	ADV
elements-9064	134	12	in	in	ADP
elements-9064	134	13	the	the	DET
elements-9064	134	14	context	context	NOUN
elements-9064	134	15	of	of	ADP
elements-9064	134	16	a	a	DET
elements-9064	134	17	restriction	restriction	NOUN
elements-9064	134	18	factor	factor	NOUN
elements-9064	134	19	.	.	PUNCT
elements-9064	135	1	polymorphisms	polymorphism	NOUN
elements-9064	135	2	that	that	PRON
elements-9064	135	3	change	change	VERB
elements-9064	135	4	the	the	DET
elements-9064	135	5	charge	charge	NOUN
elements-9064	135	6	of	of	ADP
elements-9064	135	7	the	the	DET
elements-9064	135	8	amino	amino	NOUN
elements-9064	135	9	acid	acid	NOUN
elements-9064	135	10	may	may	AUX
elements-9064	135	11	be	be	AUX
elements-9064	135	12	more	more	ADV
elements-9064	135	13	likely	likely	ADJ
elements-9064	135	14	to	to	PART
elements-9064	135	15	be	be	AUX
elements-9064	135	16	involved	involve	VERB
elements-9064	135	17	in	in	ADP
elements-9064	135	18	an	an	DET
elements-9064	135	19	evolutionary	evolutionary	ADJ
elements-9064	135	20	“	"	PUNCT
elements-9064	135	21	arms	arm	NOUN
elements-9064	135	22	race	race	NOUN
elements-9064	135	23	”	"	PUNCT
elements-9064	135	24	than	than	ADP
elements-9064	135	25	more	more	ADV
elements-9064	135	26	functionally	functionally	ADV
elements-9064	135	27	conservative	conservative	ADJ
elements-9064	135	28	polymorphisms	polymorphism	NOUN
elements-9064	135	29	.	.	PUNCT
elements-9064	136	1	examination	examination	NOUN
elements-9064	136	2	of	of	ADP
elements-9064	136	3	the	the	DET
elements-9064	136	4	inter	inter	ADJ
elements-9064	136	5	-	-	ADJ
elements-9064	136	6	species	species	ADJ
elements-9064	136	7	variation	variation	NOUN
elements-9064	136	8	via	via	ADP
elements-9064	136	9	dn	dn	ADJ
elements-9064	136	10	/	/	SYM
elements-9064	136	11	ds	ds	ADJ
elements-9064	136	12	analysis	analysis	NOUN
elements-9064	136	13	indicated	indicate	VERB
elements-9064	136	14	that	that	SCONJ
elements-9064	136	15	multiple	multiple	ADJ
elements-9064	136	16	sites	site	NOUN
elements-9064	136	17	within	within	ADP
elements-9064	136	18	the	the	DET
elements-9064	136	19	gene	gene	NOUN
elements-9064	136	20	have	have	AUX
elements-9064	136	21	been	be	AUX
elements-9064	136	22	subject	subject	ADJ
elements-9064	136	23	to	to	ADP
elements-9064	136	24	positive	positive	ADJ
elements-9064	136	25	selection	selection	NOUN
elements-9064	136	26	,	,	PUNCT
elements-9064	136	27	and	and	CCONJ
elements-9064	136	28	some	some	PRON
elements-9064	136	29	of	of	ADP
elements-9064	136	30	these	these	DET
elements-9064	136	31	sites	site	NOUN
elements-9064	136	32	overlap	overlap	VERB
elements-9064	136	33	with	with	ADP
elements-9064	136	34	the	the	DET
elements-9064	136	35	polymorphic	polymorphic	ADJ
elements-9064	136	36	sites	site	NOUN
elements-9064	136	37	found	find	VERB
elements-9064	136	38	in	in	ADP
elements-9064	136	39	rhesus	rhesus	NOUN
elements-9064	136	40	macaques	macaque	NOUN
elements-9064	136	41	.	.	PUNCT
elements-9064	137	1	it	it	PRON
elements-9064	137	2	is	be	AUX
elements-9064	137	3	important	important	ADJ
elements-9064	137	4	to	to	PART
elements-9064	137	5	note	note	VERB
elements-9064	137	6	that	that	SCONJ
elements-9064	137	7	the	the	DET
elements-9064	137	8	input	input	NOUN
elements-9064	137	9	for	for	ADP
elements-9064	137	10	dn	dn	ADJ
elements-9064	137	11	/	/	SYM
elements-9064	137	12	ds	ds	ADJ
elements-9064	137	13	analysis	analysis	NOUN
elements-9064	137	14	had	have	VERB
elements-9064	137	15	15	15	NUM
elements-9064	137	16	sequences	sequence	NOUN
elements-9064	137	17	representing	represent	VERB
elements-9064	137	18	10	10	NUM
elements-9064	137	19	different	different	ADJ
elements-9064	137	20	primate	primate	NOUN
elements-9064	137	21	species	specie	NOUN
elements-9064	137	22	.	.	PUNCT
elements-9064	138	1	this	this	PRON
elements-9064	138	2	does	do	AUX
elements-9064	138	3	not	not	PART
elements-9064	138	4	represent	represent	VERB
elements-9064	138	5	the	the	DET
elements-9064	138	6	full	full	ADJ
elements-9064	138	7	range	range	NOUN
elements-9064	138	8	of	of	ADP
elements-9064	138	9	primate	primate	NOUN
elements-9064	138	10	a3fs	a3fs	NOUN
elements-9064	138	11	,	,	PUNCT
elements-9064	138	12	and	and	CCONJ
elements-9064	138	13	the	the	DET
elements-9064	138	14	use	use	NOUN
elements-9064	138	15	of	of	ADP
elements-9064	138	16	multiple	multiple	ADJ
elements-9064	138	17	a3f	a3f	ADJ
elements-9064	138	18	variants	variant	NOUN
elements-9064	138	19	of	of	ADP
elements-9064	138	20	certain	certain	ADJ
elements-9064	138	21	species	specie	NOUN
elements-9064	138	22	may	may	AUX
elements-9064	138	23	have	have	AUX
elements-9064	138	24	artificially	artificially	ADV
elements-9064	138	25	influenced	influence	VERB
elements-9064	138	26	the	the	DET
elements-9064	138	27	results	result	NOUN
elements-9064	138	28	.	.	PUNCT
elements-9064	139	1	however	however	ADV
elements-9064	139	2	,	,	PUNCT
elements-9064	139	3	eliminating	eliminate	VERB
elements-9064	139	4	variable	variable	ADJ
elements-9064	139	5	alleles	allele	NOUN
elements-9064	139	6	of	of	ADP
elements-9064	139	7	a	a	DET
elements-9064	139	8	given	give	VERB
elements-9064	139	9	species	specie	NOUN
elements-9064	139	10	also	also	ADV
elements-9064	139	11	would	would	AUX
elements-9064	139	12	also	also	ADV
elements-9064	139	13	have	have	AUX
elements-9064	139	14	had	have	VERB
elements-9064	139	15	the	the	DET
elements-9064	139	16	potential	potential	NOUN
elements-9064	139	17	of	of	ADP
elements-9064	139	18	producing	produce	VERB
elements-9064	139	19	artificially	artificially	ADV
elements-9064	139	20	conservative	conservative	ADJ
elements-9064	139	21	results	result	NOUN
elements-9064	139	22	.	.	PUNCT
elements-9064	140	1	comparing	compare	VERB
elements-9064	140	2	results	result	NOUN
elements-9064	140	3	of	of	ADP
elements-9064	140	4	multiple	multiple	ADJ
elements-9064	140	5	analyses	analysis	NOUN
elements-9064	140	6	that	that	PRON
elements-9064	140	7	differ	differ	VERB
elements-9064	140	8	in	in	ADP
elements-9064	140	9	their	their	PRON
elements-9064	140	10	level	level	NOUN
elements-9064	140	11	of	of	ADP
elements-9064	140	12	conservativeness	conservativeness	NOUN
elements-9064	140	13	helped	help	VERB
elements-9064	140	14	to	to	PART
elements-9064	140	15	address	address	VERB
elements-9064	140	16	this	this	DET
elements-9064	140	17	issue	issue	NOUN
elements-9064	140	18	,	,	PUNCT
elements-9064	140	19	and	and	CCONJ
elements-9064	140	20	11	11	NUM
elements-9064	140	21	sites	site	NOUN
elements-9064	140	22	in	in	ADP
elements-9064	140	23	primate	primate	NOUN
elements-9064	140	24	a3f	a3f	PROPN
elements-9064	140	25	were	be	AUX
elements-9064	140	26	shown	show	VERB
elements-9064	140	27	to	to	PART
elements-9064	140	28	be	be	AUX
elements-9064	140	29	under	under	ADP
elements-9064	140	30	the	the	DET
elements-9064	140	31	influence	influence	NOUN
elements-9064	140	32	of	of	ADP
elements-9064	140	33	positive	positive	ADJ
elements-9064	140	34	selection	selection	NOUN
elements-9064	140	35	.	.	PUNCT
elements-9064	141	1	this	this	PRON
elements-9064	141	2	is	be	AUX
elements-9064	141	3	potentially	potentially	ADV
elements-9064	141	4	only	only	ADV
elements-9064	141	5	a	a	DET
elements-9064	141	6	subset	subset	NOUN
elements-9064	141	7	of	of	ADP
elements-9064	141	8	sites	site	NOUN
elements-9064	141	9	that	that	PRON
elements-9064	141	10	are	be	AUX
elements-9064	141	11	subject	subject	ADJ
elements-9064	141	12	to	to	ADP
elements-9064	141	13	positive	positive	ADJ
elements-9064	141	14	selection	selection	NOUN
elements-9064	141	15	,	,	PUNCT
elements-9064	141	16	as	as	ADP
elements-9064	141	17	the	the	DET
elements-9064	141	18	different	different	ADJ
elements-9064	141	19	analysis	analysis	NOUN
elements-9064	141	20	models	model	NOUN
elements-9064	141	21	identified	identify	VERB
elements-9064	141	22	as	as	ADV
elements-9064	141	23	many	many	ADJ
elements-9064	141	24	as	as	ADP
elements-9064	141	25	25	25	NUM
elements-9064	141	26	positively	positively	ADV
elements-9064	141	27	selected	select	VERB
elements-9064	141	28	sites	site	NOUN
elements-9064	141	29	.	.	PUNCT
elements-9064	142	1	an	an	DET
elements-9064	142	2	interesting	interesting	ADJ
elements-9064	142	3	patch	patch	NOUN
elements-9064	142	4	of	of	ADP
elements-9064	142	5	four	four	NUM
elements-9064	142	6	linked	link	VERB
elements-9064	142	7	amino	amino	NOUN
elements-9064	142	8	acids	acid	NOUN
elements-9064	142	9	was	be	AUX
elements-9064	142	10	identified	identify	VERB
elements-9064	142	11	at	at	ADP
elements-9064	142	12	codons	codon	NOUN
elements-9064	142	13	60	60	NUM
elements-9064	142	14	,	,	PUNCT
elements-9064	142	15	61	61	NUM
elements-9064	142	16	,	,	PUNCT
elements-9064	142	17	63	63	NUM
elements-9064	142	18	,	,	PUNCT
elements-9064	142	19	and	and	CCONJ
elements-9064	142	20	64	64	NUM
elements-9064	142	21	,	,	PUNCT
elements-9064	142	22	where	where	SCONJ
elements-9064	142	23	two	two	NUM
elements-9064	142	24	sequences	sequence	NOUN
elements-9064	142	25	were	be	AUX
elements-9064	142	26	found	find	VERB
elements-9064	142	27	at	at	ADP
elements-9064	142	28	similar	similar	ADJ
elements-9064	142	29	frequencies	frequency	NOUN
elements-9064	142	30	in	in	ADP
elements-9064	142	31	rha3f	rha3f	ADJ
elements-9064	142	32	clones	clone	NOUN
elements-9064	142	33	.	.	PUNCT
elements-9064	143	1	dn	dn	ADJ
elements-9064	143	2	/	/	SYM
elements-9064	143	3	ds	ds	ADJ
elements-9064	143	4	analysis	analysis	NOUN
elements-9064	143	5	suggested	suggest	VERB
elements-9064	143	6	that	that	SCONJ
elements-9064	143	7	these	these	DET
elements-9064	143	8	codons	codon	NOUN
elements-9064	143	9	have	have	AUX
elements-9064	143	10	been	be	AUX
elements-9064	143	11	subject	subject	ADJ
elements-9064	143	12	to	to	ADP
elements-9064	143	13	positive	positive	ADJ
elements-9064	143	14	selective	selective	ADJ
elements-9064	143	15	pressure	pressure	NOUN
elements-9064	143	16	.	.	PUNCT
elements-9064	144	1	the	the	DET
elements-9064	144	2	fqqy	fqqy	ADJ
elements-9064	144	3	allele	allele	NOUN
elements-9064	144	4	appeared	appear	VERB
elements-9064	144	5	at	at	ADP
elements-9064	144	6	a	a	DET
elements-9064	144	7	slightly	slightly	ADV
elements-9064	144	8	higher	high	ADJ
elements-9064	144	9	frequency	frequency	NOUN
elements-9064	144	10	than	than	ADP
elements-9064	144	11	the	the	DET
elements-9064	144	12	skeh	skeh	ADJ
elements-9064	144	13	allele	allele	NOUN
elements-9064	144	14	in	in	ADP
elements-9064	144	15	a	a	DET
elements-9064	144	16	broader	broad	ADJ
elements-9064	144	17	genomic	genomic	ADJ
elements-9064	144	18	analysis	analysis	NOUN
elements-9064	144	19	of	of	ADP
elements-9064	144	20	the	the	DET
elements-9064	144	21	region	region	NOUN
elements-9064	144	22	in	in	ADP
elements-9064	144	23	rhesus	rhesus	NOUN
elements-9064	144	24	macaques	macaque	NOUN
elements-9064	144	25	;	;	PUNCT
elements-9064	144	26	however	however	ADV
elements-9064	144	27	,	,	PUNCT
elements-9064	144	28	the	the	DET
elements-9064	144	29	less	less	ADV
elements-9064	144	30	common	common	ADJ
elements-9064	144	31	skeh	skeh	ADJ
elements-9064	144	32	haplotype	haplotype	NOUN
elements-9064	144	33	did	do	AUX
elements-9064	144	34	appear	appear	VERB
elements-9064	144	35	across	across	ADP
elements-9064	144	36	multiple	multiple	ADJ
elements-9064	144	37	animals	animal	NOUN
elements-9064	144	38	and	and	CCONJ
elements-9064	144	39	clones	clone	NOUN
elements-9064	144	40	,	,	PUNCT
elements-9064	144	41	unlike	unlike	ADP
elements-9064	144	42	many	many	ADJ
elements-9064	144	43	other	other	ADJ
elements-9064	144	44	polymorphic	polymorphic	ADJ
elements-9064	144	45	sites	site	NOUN
elements-9064	144	46	where	where	SCONJ
elements-9064	144	47	the	the	DET
elements-9064	144	48	less	less	ADV
elements-9064	144	49	common	common	ADJ
elements-9064	144	50	allele	allele	NOUN
elements-9064	144	51	appeared	appear	VERB
elements-9064	144	52	at	at	ADP
elements-9064	144	53	a	a	DET
elements-9064	144	54	significantly	significantly	ADV
elements-9064	144	55	lower	low	ADJ
elements-9064	144	56	frequency	frequency	NOUN
elements-9064	144	57	and	and	CCONJ
elements-9064	144	58	sometimes	sometimes	ADV
elements-9064	144	59	only	only	ADV
elements-9064	144	60	in	in	ADP
elements-9064	144	61	one	one	NUM
elements-9064	144	62	animal	animal	NOUN
elements-9064	144	63	.	.	PUNCT
elements-9064	145	1	the	the	DET
elements-9064	145	2	changes	change	NOUN
elements-9064	145	3	at	at	ADP
elements-9064	145	4	the	the	DET
elements-9064	145	5	amino	amino	NOUN
elements-9064	145	6	acid	acid	NOUN
elements-9064	145	7	level	level	NOUN
elements-9064	145	8	in	in	ADP
elements-9064	145	9	this	this	DET
elements-9064	145	10	patch	patch	NOUN
elements-9064	145	11	are	be	AUX
elements-9064	145	12	rather	rather	ADV
elements-9064	145	13	significant	significant	ADJ
elements-9064	145	14	,	,	PUNCT
elements-9064	145	15	as	as	SCONJ
elements-9064	145	16	three	three	NUM
elements-9064	145	17	charged	charge	VERB
elements-9064	145	18	amino	amino	NOUN
elements-9064	145	19	acids	acid	NOUN
elements-9064	145	20	are	be	AUX
elements-9064	145	21	introduced	introduce	VERB
elements-9064	145	22	in	in	ADP
elements-9064	145	23	the	the	DET
elements-9064	145	24	skeh	skeh	ADJ
elements-9064	145	25	haplotype	haplotype	NOUN
elements-9064	145	26	while	while	SCONJ
elements-9064	145	27	the	the	DET
elements-9064	145	28	patch	patch	NOUN
elements-9064	145	29	is	be	AUX
elements-9064	145	30	neutral	neutral	ADJ
elements-9064	145	31	in	in	ADP
elements-9064	145	32	the	the	DET
elements-9064	145	33	fqqy	fqqy	ADJ
elements-9064	145	34	haplotype	haplotype	NOUN
elements-9064	145	35	.	.	PUNCT
elements-9064	146	1	this	this	DET
elements-9064	146	2	patch	patch	NOUN
elements-9064	146	3	was	be	AUX
elements-9064	146	4	also	also	ADV
elements-9064	146	5	notable	notable	ADJ
elements-9064	146	6	because	because	SCONJ
elements-9064	146	7	of	of	ADP
elements-9064	146	8	its	its	PRON
elements-9064	146	9	location	location	NOUN
elements-9064	146	10	in	in	ADP
elements-9064	146	11	the	the	DET
elements-9064	146	12	structure	structure	NOUN
elements-9064	146	13	of	of	ADP
elements-9064	146	14	a3f	a3f	PROPN
elements-9064	146	15	.	.	PUNCT
elements-9064	147	1	it	it	PRON
elements-9064	147	2	borders	border	VERB
elements-9064	147	3	the	the	DET
elements-9064	147	4	n	n	CCONJ
elements-9064	147	5	-	-	PUNCT
elements-9064	147	6	terminal	terminal	ADJ
elements-9064	147	7	catalytic	catalytic	ADJ
elements-9064	147	8	motif	motif	NOUN
elements-9064	147	9	,	,	PUNCT
elements-9064	147	10	and	and	CCONJ
elements-9064	147	11	is	be	AUX
elements-9064	147	12	adjacent	adjacent	ADJ
elements-9064	147	13	to	to	ADP
elements-9064	147	14	a	a	DET
elements-9064	147	15	known	know	VERB
elements-9064	147	16	determinant	determinant	NOUN
elements-9064	147	17	of	of	ADP
elements-9064	147	18	strain	strain	NOUN
elements-9064	147	19	-	-	PUNCT
elements-9064	147	20	specific	specific	ADJ
elements-9064	147	21	resistance	resistance	NOUN
elements-9064	147	22	to	to	ADP
elements-9064	147	23	siv	siv	NOUN
elements-9064	147	24	-	-	PUNCT
elements-9064	147	25	vif	vif	NOUN
elements-9064	147	26	mediated	mediate	VERB
elements-9064	147	27	degradation	degradation	NOUN
elements-9064	147	28	in	in	ADP
elements-9064	147	29	a3	a3	NOUN
elements-9064	147	30	g.	g.	NOUN
elements-9064	147	31	polymorphism	polymorphism	NOUN
elements-9064	147	32	at	at	ADP
elements-9064	147	33	residue	residue	NOUN
elements-9064	147	34	59	59	NUM
elements-9064	147	35	in	in	ADP
elements-9064	147	36	rha3	rha3	PROPN
elements-9064	147	37	g	g	PROPN
elements-9064	147	38	confers	confer	NOUN
elements-9064	147	39	variable	variable	ADJ
elements-9064	147	40	susceptibility	susceptibility	NOUN
elements-9064	147	41	to	to	ADP
elements-9064	147	42	degradation	degradation	NOUN
elements-9064	147	43	by	by	ADP
elements-9064	147	44	sivmac	sivmac	PROPN
elements-9064	147	45	vif.49	vif.49	PROPN
elements-9064	147	46	together	together	ADV
elements-9064	147	47	,	,	PUNCT
elements-9064	147	48	these	these	DET
elements-9064	147	49	observations	observation	NOUN
elements-9064	147	50	suggest	suggest	VERB
elements-9064	147	51	that	that	SCONJ
elements-9064	147	52	this	this	DET
elements-9064	147	53	patch	patch	NOUN
elements-9064	147	54	may	may	AUX
elements-9064	147	55	play	play	VERB
elements-9064	147	56	a	a	DET
elements-9064	147	57	key	key	ADJ
elements-9064	147	58	role	role	NOUN
elements-9064	147	59	in	in	ADP
elements-9064	147	60	an	an	DET
elements-9064	147	61	interaction	interaction	NOUN
elements-9064	147	62	with	with	ADP
elements-9064	147	63	a	a	DET
elements-9064	147	64	viral	viral	ADJ
elements-9064	147	65	protein	protein	NOUN
elements-9064	147	66	,	,	PUNCT
elements-9064	147	67	particularly	particularly	ADV
elements-9064	147	68	with	with	ADP
elements-9064	147	69	siv	siv	PROPN
elements-9064	147	70	vif	vif	PROPN
elements-9064	147	71	.	.	PUNCT
elements-9064	148	1	however	however	ADV
elements-9064	148	2	,	,	PUNCT
elements-9064	148	3	functional	functional	ADJ
elements-9064	148	4	tests	test	NOUN
elements-9064	148	5	did	do	AUX
elements-9064	148	6	not	not	PART
elements-9064	148	7	suggest	suggest	VERB
elements-9064	148	8	that	that	SCONJ
elements-9064	148	9	variation	variation	NOUN
elements-9064	148	10	at	at	ADP
elements-9064	148	11	this	this	DET
elements-9064	148	12	site	site	NOUN
elements-9064	148	13	plays	play	VERB
elements-9064	148	14	a	a	DET
elements-9064	148	15	role	role	NOUN
elements-9064	148	16	in	in	ADP
elements-9064	148	17	determining	determine	VERB
elements-9064	148	18	susceptibility	susceptibility	NOUN
elements-9064	148	19	to	to	ADP
elements-9064	148	20	vif	vif	PROPN
elements-9064	148	21	,	,	PUNCT
elements-9064	148	22	as	as	SCONJ
elements-9064	148	23	rha3f	rha3f	ADJ
elements-9064	148	24	clones	clone	NOUN
elements-9064	148	25	that	that	PRON
elements-9064	148	26	contained	contain	VERB
elements-9064	148	27	variable	variable	ADJ
elements-9064	148	28	patch	patch	NOUN
elements-9064	148	29	alleles	allele	NOUN
elements-9064	148	30	did	do	AUX
elements-9064	148	31	not	not	PART
elements-9064	148	32	display	display	VERB
elements-9064	148	33	differential	differential	ADJ
elements-9064	148	34	resistance	resistance	NOUN
elements-9064	148	35	to	to	ADP
elements-9064	148	36	vifs	vif	NOUN
elements-9064	148	37	from	from	ADP
elements-9064	148	38	various	various	ADJ
elements-9064	148	39	siv	siv	PROPN
elements-9064	148	40	strains	strain	NOUN
elements-9064	148	41	.	.	PUNCT
elements-9064	149	1	despite	despite	SCONJ
elements-9064	149	2	this	this	DET
elements-9064	149	3	patch	patch	NOUN
elements-9064	149	4	’s	’s	PART
elements-9064	149	5	proximity	proximity	NOUN
elements-9064	149	6	to	to	ADP
elements-9064	149	7	residue	residue	NOUN
elements-9064	149	8	59	59	NUM
elements-9064	149	9	,	,	PUNCT
elements-9064	149	10	it	it	PRON
elements-9064	149	11	is	be	AUX
elements-9064	149	12	not	not	PART
elements-9064	149	13	necessarily	necessarily	ADV
elements-9064	149	14	surprising	surprising	ADJ
elements-9064	149	15	that	that	SCONJ
elements-9064	149	16	it	it	PRON
elements-9064	149	17	does	do	AUX
elements-9064	149	18	not	not	PART
elements-9064	149	19	play	play	VERB
elements-9064	149	20	a	a	DET
elements-9064	149	21	role	role	NOUN
elements-9064	149	22	in	in	ADP
elements-9064	149	23	rhesus	rhesus	NOUN
elements-9064	149	24	a3f	a3f	ADJ
elements-9064	149	25	interaction	interaction	NOUN
elements-9064	149	26	with	with	ADP
elements-9064	149	27	vif	vif	PROPN
elements-9064	149	28	.	.	PUNCT
elements-9064	150	1	it	it	PRON
elements-9064	150	2	is	be	AUX
elements-9064	150	3	known	know	VERB
elements-9064	150	4	that	that	SCONJ
elements-9064	150	5	hiv-1	hiv-1	PUNCT
elements-9064	150	6	vif	vif	NOUN
elements-9064	150	7	interacts	interact	VERB
elements-9064	150	8	with	with	ADP
elements-9064	150	9	the	the	DET
elements-9064	150	10	ctd	ctd	NOUN
elements-9064	150	11	in	in	ADP
elements-9064	150	12	a3f	a3f	PROPN
elements-9064	150	13	,	,	PUNCT
elements-9064	150	14	unlike	unlike	ADP
elements-9064	150	15	in	in	ADP
elements-9064	150	16	a3	a3	NOUN
elements-9064	150	17	g	g	PROPN
elements-9064	150	18	where	where	SCONJ
elements-9064	150	19	it	it	PRON
elements-9064	150	20	interacts	interact	VERB
elements-9064	150	21	with	with	ADP
elements-9064	150	22	the	the	DET
elements-9064	150	23	ntd	ntd	NOUN
elements-9064	150	24	.	.	PUNCT
elements-9064	151	1	while	while	SCONJ
elements-9064	151	2	this	this	DET
elements-9064	151	3	interaction	interaction	NOUN
elements-9064	151	4	has	have	AUX
elements-9064	151	5	not	not	PART
elements-9064	151	6	been	be	AUX
elements-9064	151	7	precisely	precisely	ADV
elements-9064	151	8	“	"	PUNCT
elements-9064	151	9	the	the	DET
elements-9064	151	10	interaction	interaction	NOUN
elements-9064	151	11	between	between	ADP
elements-9064	151	12	a3s	a3s	PROPN
elements-9064	151	13	and	and	CCONJ
elements-9064	151	14	vif	vif	NOUN
elements-9064	151	15	is	be	AUX
elements-9064	151	16	a	a	DET
elements-9064	151	17	crucial	crucial	ADJ
elements-9064	151	18	determinant	determinant	NOUN
elements-9064	151	19	of	of	ADP
elements-9064	151	20	the	the	DET
elements-9064	151	21	species	specie	NOUN
elements-9064	151	22	specificity	specificity	NOUN
elements-9064	151	23	of	of	ADP
elements-9064	151	24	a	a	DET
elements-9064	151	25	virus	virus	NOUN
elements-9064	151	26	,	,	PUNCT
elements-9064	151	27	and	and	CCONJ
elements-9064	151	28	it	it	PRON
elements-9064	151	29	is	be	AUX
elements-9064	151	30	likely	likely	ADJ
elements-9064	151	31	that	that	SCONJ
elements-9064	151	32	a	a	DET
elements-9064	151	33	vif	vif	NOUN
elements-9064	151	34	from	from	ADP
elements-9064	151	35	a	a	DET
elements-9064	151	36	given	give	VERB
elements-9064	151	37	viral	viral	ADJ
elements-9064	151	38	strain	strain	NOUN
elements-9064	151	39	has	have	AUX
elements-9064	151	40	evolved	evolve	VERB
elements-9064	151	41	precisely	precisely	ADV
elements-9064	151	42	to	to	PART
elements-9064	151	43	counteract	counteract	VERB
elements-9064	151	44	the	the	DET
elements-9064	151	45	a3	a3	NOUN
elements-9064	151	46	proteins	protein	NOUN
elements-9064	151	47	of	of	ADP
elements-9064	151	48	its	its	PRON
elements-9064	151	49	host	host	NOUN
elements-9064	151	50	species	specie	NOUN
elements-9064	151	51	.	.	PUNCT
elements-9064	151	52	”	"	PUNCT
elements-9064	152	1	55	55	NUM
elements-9064	152	2	a	a	DET
elements-9064	152	3	biological	biological	ADJ
elements-9064	152	4	“	"	PUNCT
elements-9064	152	5	arms	arm	NOUN
elements-9064	152	6	race	race	NOUN
elements-9064	152	7	”	"	PUNCT
elements-9064	152	8	mapped	map	VERB
elements-9064	152	9	with	with	ADP
elements-9064	152	10	siv	siv	PROPN
elements-9064	152	11	vifs	vifs	PROPN
elements-9064	152	12	,	,	PUNCT
elements-9064	152	13	it	it	PRON
elements-9064	152	14	is	be	AUX
elements-9064	152	15	reasonable	reasonable	ADJ
elements-9064	152	16	to	to	PART
elements-9064	152	17	believe	believe	VERB
elements-9064	152	18	that	that	SCONJ
elements-9064	152	19	they	they	PRON
elements-9064	152	20	will	will	AUX
elements-9064	152	21	behave	behave	VERB
elements-9064	152	22	analogously	analogously	ADV
elements-9064	152	23	to	to	ADP
elements-9064	152	24	hiv-1	hiv-1	X
elements-9064	152	25	vif	vif	NOUN
elements-9064	152	26	and	and	CCONJ
elements-9064	152	27	interact	interact	VERB
elements-9064	152	28	at	at	ADP
elements-9064	152	29	the	the	DET
elements-9064	152	30	ctd	ctd	NOUN
elements-9064	152	31	in	in	ADP
elements-9064	152	32	a3f	a3f	PROPN
elements-9064	152	33	.	.	PUNCT
elements-9064	153	1	therefore	therefore	ADV
elements-9064	153	2	,	,	PUNCT
elements-9064	153	3	this	this	DET
elements-9064	153	4	ntd	ntd	NOUN
elements-9064	153	5	patch	patch	NOUN
elements-9064	153	6	would	would	AUX
elements-9064	153	7	not	not	PART
elements-9064	153	8	be	be	AUX
elements-9064	153	9	expected	expect	VERB
elements-9064	153	10	to	to	PART
elements-9064	153	11	play	play	VERB
elements-9064	153	12	a	a	DET
elements-9064	153	13	direct	direct	ADJ
elements-9064	153	14	role	role	NOUN
elements-9064	153	15	in	in	ADP
elements-9064	153	16	interactions	interaction	NOUN
elements-9064	153	17	with	with	ADP
elements-9064	153	18	vif	vif	PROPN
elements-9064	153	19	.	.	PUNCT
elements-9064	154	1	functional	functional	ADJ
elements-9064	154	2	tests	test	NOUN
elements-9064	154	3	did	do	AUX
elements-9064	154	4	reveal	reveal	VERB
elements-9064	154	5	multiple	multiple	ADJ
elements-9064	154	6	surprising	surprising	ADJ
elements-9064	154	7	phenotypes	phenotype	NOUN
elements-9064	154	8	relating	relate	VERB
elements-9064	154	9	to	to	ADP
elements-9064	154	10	the	the	DET
elements-9064	154	11	siv	siv	PROPN
elements-9064	154	12	vifs	vifs	PROPN
elements-9064	154	13	.	.	PUNCT
elements-9064	155	1	the	the	DET
elements-9064	155	2	rha3f	rha3f	ADJ
elements-9064	155	3	clones	clone	NOUN
elements-9064	155	4	tested	test	VERB
elements-9064	155	5	displayed	display	VERB
elements-9064	155	6	resistance	resistance	NOUN
elements-9064	155	7	to	to	ADP
elements-9064	155	8	degradation	degradation	NOUN
elements-9064	155	9	by	by	ADP
elements-9064	155	10	sivmac	sivmac	PROPN
elements-9064	155	11	vif	vif	PROPN
elements-9064	155	12	.	.	PUNCT
elements-9064	156	1	sivmac239	sivmac239	PROPN
elements-9064	156	2	is	be	AUX
elements-9064	156	3	a	a	DET
elements-9064	156	4	cloned	cloned	ADJ
elements-9064	156	5	viral	viral	ADJ
elements-9064	156	6	isolate	isolate	NOUN
elements-9064	156	7	that	that	PRON
elements-9064	156	8	is	be	AUX
elements-9064	156	9	well	well	ADV
elements-9064	156	10	adapted	adapt	VERB
elements-9064	156	11	to	to	ADP
elements-9064	156	12	its	its	PRON
elements-9064	156	13	rhesus	rhesus	NOUN
elements-9064	156	14	macaque	macaque	ADJ
elements-9064	156	15	host	host	NOUN
elements-9064	156	16	.	.	PUNCT
elements-9064	157	1	thus	thus	ADV
elements-9064	157	2	,	,	PUNCT
elements-9064	157	3	one	one	PRON
elements-9064	157	4	would	would	AUX
elements-9064	157	5	expect	expect	VERB
elements-9064	157	6	the	the	DET
elements-9064	157	7	vif	vif	NOUN
elements-9064	157	8	derived	derive	VERB
elements-9064	157	9	from	from	ADP
elements-9064	157	10	this	this	DET
elements-9064	157	11	macaque	macaque	ADJ
elements-9064	157	12	-	-	PUNCT
elements-9064	157	13	adapted	adapt	VERB
elements-9064	157	14	virus	virus	NOUN
elements-9064	157	15	to	to	PART
elements-9064	157	16	degrade	degrade	VERB
elements-9064	157	17	the	the	DET
elements-9064	157	18	rha3f	rha3f	ADJ
elements-9064	157	19	clones	clone	NOUN
elements-9064	157	20	,	,	PUNCT
elements-9064	157	21	yet	yet	CCONJ
elements-9064	157	22	this	this	PRON
elements-9064	157	23	was	be	AUX
elements-9064	157	24	not	not	PART
elements-9064	157	25	observed	observe	VERB
elements-9064	157	26	.	.	PUNCT
elements-9064	158	1	rha3f	rha3f	ADJ
elements-9064	158	2	function	function	NOUN
elements-9064	158	3	was	be	AUX
elements-9064	158	4	further	far	ADV
elements-9064	158	5	tested	test	VERB
elements-9064	158	6	against	against	ADP
elements-9064	158	7	a	a	DET
elements-9064	158	8	more	more	ADV
elements-9064	158	9	diverse	diverse	ADJ
elements-9064	158	10	panel	panel	NOUN
elements-9064	158	11	of	of	ADP
elements-9064	158	12	macaqueadapted	macaqueadapte	VERB
elements-9064	158	13	vifs	vif	NOUN
elements-9064	158	14	(	(	PUNCT
elements-9064	158	15	data	datum	NOUN
elements-9064	158	16	not	not	PART
elements-9064	158	17	shown	show	VERB
elements-9064	158	18	)	)	PUNCT
elements-9064	158	19	,	,	PUNCT
elements-9064	158	20	and	and	CCONJ
elements-9064	158	21	similarly	similarly	ADV
elements-9064	158	22	to	to	ADP
elements-9064	158	23	the	the	DET
elements-9064	158	24	sivmac239	sivmac239	PROPN
elements-9064	158	25	isolate	isolate	NOUN
elements-9064	158	26	,	,	PUNCT
elements-9064	158	27	the	the	DET
elements-9064	158	28	rha3f	rha3f	ADJ
elements-9064	158	29	alleles	allele	NOUN
elements-9064	158	30	were	be	AUX
elements-9064	158	31	resistant	resistant	ADJ
elements-9064	158	32	to	to	ADP
elements-9064	158	33	degradation	degradation	NOUN
elements-9064	158	34	.	.	PUNCT
elements-9064	159	1	thus	thus	ADV
elements-9064	159	2	,	,	PUNCT
elements-9064	159	3	this	this	DET
elements-9064	159	4	phenotype	phenotype	NOUN
elements-9064	159	5	does	do	AUX
elements-9064	159	6	not	not	PART
elements-9064	159	7	appear	appear	VERB
elements-9064	159	8	to	to	PART
elements-9064	159	9	be	be	AUX
elements-9064	159	10	a	a	DET
elements-9064	159	11	specific	specific	ADJ
elements-9064	159	12	phenomenon	phenomenon	NOUN
elements-9064	159	13	of	of	ADP
elements-9064	159	14	the	the	DET
elements-9064	159	15	sivmac239	sivmac239	PROPN
elements-9064	159	16	isolate	isolate	NOUN
elements-9064	159	17	,	,	PUNCT
elements-9064	159	18	but	but	CCONJ
elements-9064	159	19	rather	rather	ADV
elements-9064	159	20	a	a	DET
elements-9064	159	21	more	more	ADV
elements-9064	159	22	general	general	ADJ
elements-9064	159	23	property	property	NOUN
elements-9064	159	24	of	of	ADP
elements-9064	159	25	rha3f	rha3f	PROPN
elements-9064	159	26	.	.	PUNCT
elements-9064	160	1	it	it	PRON
elements-9064	160	2	is	be	AUX
elements-9064	160	3	important	important	ADJ
elements-9064	160	4	to	to	PART
elements-9064	160	5	note	note	VERB
elements-9064	160	6	that	that	SCONJ
elements-9064	160	7	the	the	DET
elements-9064	160	8	rha3	rha3	PROPN
elements-9064	160	9	g	g	PROPN
elements-9064	160	10	controls	control	NOUN
elements-9064	160	11	confirm	confirm	VERB
elements-9064	160	12	that	that	SCONJ
elements-9064	160	13	this	this	DET
elements-9064	160	14	sivmac239	sivmac239	PROPN
elements-9064	160	15	vif	vif	PROPN
elements-9064	160	16	clone	clone	NOUN
elements-9064	160	17	is	be	AUX
elements-9064	160	18	active	active	ADJ
elements-9064	160	19	and	and	CCONJ
elements-9064	160	20	behaves	behave	VERB
elements-9064	160	21	as	as	SCONJ
elements-9064	160	22	expected	expect	VERB
elements-9064	160	23	with	with	ADP
elements-9064	160	24	these	these	DET
elements-9064	160	25	rha3	rha3	PROPN
elements-9064	160	26	g	g	NOUN
elements-9064	160	27	alleles	allele	NOUN
elements-9064	160	28	.	.	PUNCT
elements-9064	161	1	it	it	PRON
elements-9064	161	2	is	be	AUX
elements-9064	161	3	possible	possible	ADJ
elements-9064	161	4	to	to	PART
elements-9064	161	5	speculate	speculate	VERB
elements-9064	161	6	that	that	SCONJ
elements-9064	161	7	sivmac239	sivmac239	PROPN
elements-9064	161	8	evolved	evolve	VERB
elements-9064	161	9	to	to	PART
elements-9064	161	10	effectively	effectively	ADV
elements-9064	161	11	counteract	counteract	VERB
elements-9064	161	12	rha3	rha3	PROPN
elements-9064	161	13	g	g	PROPN
elements-9064	161	14	,	,	PUNCT
elements-9064	161	15	the	the	DET
elements-9064	161	16	more	more	ADV
elements-9064	161	17	potent	potent	ADJ
elements-9064	161	18	deaminase	deaminase	NOUN
elements-9064	161	19	,	,	PUNCT
elements-9064	161	20	but	but	CCONJ
elements-9064	161	21	in	in	ADP
elements-9064	161	22	doing	do	VERB
elements-9064	161	23	so	so	ADV
elements-9064	161	24	it	it	PRON
elements-9064	161	25	traded	trade	VERB
elements-9064	161	26	off	off	ADP
elements-9064	161	27	the	the	DET
elements-9064	161	28	ability	ability	NOUN
elements-9064	161	29	to	to	PART
elements-9064	161	30	neutralize	neutralize	VERB
elements-9064	161	31	rha3f	rha3f	PROPN
elements-9064	161	32	.	.	PUNCT
elements-9064	162	1	this	this	DET
elements-9064	162	2	proposal	proposal	NOUN
elements-9064	162	3	is	be	AUX
elements-9064	162	4	supported	support	VERB
elements-9064	162	5	by	by	ADP
elements-9064	162	6	the	the	DET
elements-9064	162	7	fact	fact	NOUN
elements-9064	162	8	that	that	SCONJ
elements-9064	162	9	the	the	DET
elements-9064	162	10	more	more	ADV
elements-9064	162	11	ancestral	ancestral	ADJ
elements-9064	162	12	sivsme041	sivsme041	PROPN
elements-9064	162	13	vif	vif	NOUN
elements-9064	162	14	completely	completely	ADV
elements-9064	162	15	degraded	degrade	VERB
elements-9064	162	16	the	the	DET
elements-9064	162	17	rha3f	rha3f	ADJ
elements-9064	162	18	clones	clone	NOUN
elements-9064	162	19	tested	test	VERB
elements-9064	162	20	,	,	PUNCT
elements-9064	162	21	with	with	ADP
elements-9064	162	22	the	the	DET
elements-9064	162	23	exception	exception	NOUN
elements-9064	162	24	of	of	ADP
elements-9064	162	25	rha3f	rha3f	PROPN
elements-9064	162	26	-	-	PROPN
elements-9064	162	27	wi	wi	PROPN
elements-9064	162	28	,	,	PUNCT
elements-9064	162	29	which	which	PRON
elements-9064	162	30	showed	show	VERB
elements-9064	162	31	an	an	DET
elements-9064	162	32	intermediate	intermediate	ADJ
elements-9064	162	33	phenotype	phenotype	NOUN
elements-9064	162	34	.	.	PUNCT
elements-9064	163	1	a3f	a3f	PROPN
elements-9064	163	2	is	be	AUX
elements-9064	163	3	known	know	VERB
elements-9064	163	4	to	to	PART
elements-9064	163	5	restrict	restrict	VERB
elements-9064	163	6	viruses	virus	NOUN
elements-9064	163	7	other	other	ADJ
elements-9064	163	8	than	than	ADP
elements-9064	163	9	lentiviruses	lentiviruse	NOUN
elements-9064	163	10	,	,	PUNCT
elements-9064	163	11	so	so	SCONJ
elements-9064	163	12	it	it	PRON
elements-9064	163	13	is	be	AUX
elements-9064	163	14	reasonable	reasonable	ADJ
elements-9064	163	15	to	to	PART
elements-9064	163	16	believe	believe	VERB
elements-9064	163	17	that	that	SCONJ
elements-9064	163	18	a	a	DET
elements-9064	163	19	different	different	ADJ
elements-9064	163	20	retrovirus	retrovirus	NOUN
elements-9064	163	21	may	may	AUX
elements-9064	163	22	be	be	AUX
elements-9064	163	23	responsible	responsible	ADJ
elements-9064	163	24	for	for	ADP
elements-9064	163	25	driving	drive	VERB
elements-9064	163	26	this	this	DET
elements-9064	163	27	high	high	ADJ
elements-9064	163	28	level	level	NOUN
elements-9064	163	29	of	of	ADP
elements-9064	163	30	diversity	diversity	NOUN
elements-9064	163	31	in	in	ADP
elements-9064	163	32	rhesus	rhesus	NOUN
elements-9064	163	33	macaque	macaque	PROPN
elements-9064	163	34	a3f	a3f	PROPN
elements-9064	163	35	.	.	PUNCT
elements-9064	164	1	a	a	DET
elements-9064	164	2	potential	potential	ADJ
elements-9064	164	3	candidate	candidate	NOUN
elements-9064	164	4	is	be	AUX
elements-9064	164	5	simian	simian	ADJ
elements-9064	164	6	foamy	foamy	ADJ
elements-9064	164	7	virus	virus	NOUN
elements-9064	164	8	(	(	PUNCT
elements-9064	164	9	sfv	sfv	PROPN
elements-9064	164	10	)	)	PUNCT
elements-9064	164	11	,	,	PUNCT
elements-9064	164	12	a	a	DET
elements-9064	164	13	member	member	NOUN
elements-9064	164	14	of	of	ADP
elements-9064	164	15	the	the	DET
elements-9064	164	16	spumavirus	spumavirus	NOUN
elements-9064	164	17	genus	genus	NOUN
elements-9064	164	18	of	of	ADP
elements-9064	164	19	retroviruses	retrovirus	NOUN
elements-9064	164	20	.	.	PUNCT
elements-9064	165	1	fvs	fvs	PROPN
elements-9064	165	2	are	be	AUX
elements-9064	165	3	distinct	distinct	ADJ
elements-9064	165	4	from	from	ADP
elements-9064	165	5	other	other	ADJ
elements-9064	165	6	retroviruses	retrovirus	NOUN
elements-9064	165	7	in	in	ADP
elements-9064	165	8	many	many	ADJ
elements-9064	165	9	aspects	aspect	NOUN
elements-9064	165	10	,	,	PUNCT
elements-9064	165	11	including	include	VERB
elements-9064	165	12	their	their	PRON
elements-9064	165	13	gene	gene	NOUN
elements-9064	165	14	expression	expression	NOUN
elements-9064	165	15	,	,	PUNCT
elements-9064	165	16	protein	protein	NOUN
elements-9064	165	17	processing	processing	NOUN
elements-9064	165	18	,	,	PUNCT
elements-9064	165	19	and	and	CCONJ
elements-9064	165	20	replication	replication	NOUN
elements-9064	165	21	.	.	PUNCT
elements-9064	166	1	they	they	PRON
elements-9064	166	2	are	be	AUX
elements-9064	166	3	found	find	VERB
elements-9064	166	4	in	in	ADP
elements-9064	166	5	non	non	ADJ
elements-9064	166	6	-	-	ADJ
elements-9064	166	7	human	human	ADJ
elements-9064	166	8	primates	primate	NOUN
elements-9064	166	9	,	,	PUNCT
elements-9064	166	10	cats	cat	NOUN
elements-9064	166	11	,	,	PUNCT
elements-9064	166	12	cows	cow	NOUN
elements-9064	166	13	,	,	PUNCT
elements-9064	166	14	and	and	CCONJ
elements-9064	166	15	horses	horse	NOUN
elements-9064	166	16	,	,	PUNCT
elements-9064	166	17	as	as	ADV
elements-9064	166	18	well	well	ADV
elements-9064	166	19	as	as	ADP
elements-9064	166	20	humans	human	NOUN
elements-9064	166	21	who	who	PRON
elements-9064	166	22	have	have	AUX
elements-9064	166	23	been	be	AUX
elements-9064	166	24	infected	infect	VERB
elements-9064	166	25	by	by	ADP
elements-9064	166	26	non	non	ADJ
elements-9064	166	27	-	-	ADJ
elements-9064	166	28	human	human	ADJ
elements-9064	166	29	primates	primate	NOUN
elements-9064	166	30	.	.	PUNCT
elements-9064	167	1	they	they	PRON
elements-9064	167	2	cause	cause	VERB
elements-9064	167	3	a	a	DET
elements-9064	167	4	persistent	persistent	ADJ
elements-9064	167	5	infection	infection	NOUN
elements-9064	167	6	,	,	PUNCT
elements-9064	167	7	but	but	CCONJ
elements-9064	167	8	there	there	PRON
elements-9064	167	9	are	be	VERB
elements-9064	167	10	no	no	DET
elements-9064	167	11	known	know	VERB
elements-9064	167	12	pathologies	pathology	NOUN
elements-9064	167	13	in	in	ADP
elements-9064	167	14	natural	natural	ADJ
elements-9064	167	15	or	or	CCONJ
elements-9064	167	16	human	human	ADJ
elements-9064	167	17	hosts.50,51	hosts.50,51	NOUN
elements-9064	167	18	it	it	PRON
elements-9064	167	19	has	have	AUX
elements-9064	167	20	been	be	AUX
elements-9064	167	21	suggested	suggest	VERB
elements-9064	167	22	that	that	SCONJ
elements-9064	167	23	sfvs	sfvs	PROPN
elements-9064	167	24	have	have	AUX
elements-9064	167	25	coevolved	coevolve	VERB
elements-9064	167	26	with	with	ADP
elements-9064	167	27	their	their	PRON
elements-9064	167	28	old	old	ADJ
elements-9064	167	29	world	world	NOUN
elements-9064	167	30	primate	primate	NOUN
elements-9064	167	31	hosts	host	NOUN
elements-9064	167	32	for	for	ADP
elements-9064	167	33	over	over	ADP
elements-9064	167	34	30	30	NUM
elements-9064	167	35	million	million	NUM
elements-9064	167	36	years	year	NOUN
elements-9064	167	37	,	,	PUNCT
elements-9064	167	38	marking	mark	VERB
elements-9064	167	39	them	they	PRON
elements-9064	167	40	as	as	SCONJ
elements-9064	167	41	the	the	DET
elements-9064	167	42	oldest	old	ADJ
elements-9064	167	43	known	know	VERB
elements-9064	167	44	rna	rna	NOUN
elements-9064	167	45	viruses	virus	NOUN
elements-9064	167	46	in	in	ADP
elements-9064	167	47	vertebrates.52	vertebrates.52	NOUN
elements-9064	167	48	a3	a3	NOUN
elements-9064	167	49	proteins	protein	NOUN
elements-9064	167	50	have	have	AUX
elements-9064	167	51	been	be	AUX
elements-9064	167	52	implicated	implicate	VERB
elements-9064	167	53	in	in	ADP
elements-9064	167	54	restriction	restriction	NOUN
elements-9064	167	55	of	of	ADP
elements-9064	167	56	fvs	fvs	NOUN
elements-9064	167	57	,	,	PUNCT
elements-9064	167	58	and	and	CCONJ
elements-9064	167	59	the	the	DET
elements-9064	167	60	fv	fv	NOUN
elements-9064	167	61	accessory	accessory	NOUN
elements-9064	167	62	protein	protein	NOUN
elements-9064	167	63	bet	bet	NOUN
elements-9064	167	64	has	have	AUX
elements-9064	167	65	been	be	AUX
elements-9064	167	66	found	find	VERB
elements-9064	167	67	to	to	PART
elements-9064	167	68	counteract	counteract	VERB
elements-9064	167	69	a3	a3	NOUN
elements-9064	167	70	restriction	restriction	NOUN
elements-9064	167	71	mechanisms	mechanism	NOUN
elements-9064	167	72	analogously	analogously	ADV
elements-9064	167	73	to	to	ADP
elements-9064	167	74	hiv-1	hiv-1	X
elements-9064	167	75	vif.53,54	vif.53,54	VERB
elements-9064	167	76	the	the	DET
elements-9064	167	77	relatively	relatively	ADV
elements-9064	167	78	old	old	ADJ
elements-9064	167	79	age	age	NOUN
elements-9064	167	80	of	of	ADP
elements-9064	167	81	fvs	fvs	NOUN
elements-9064	167	82	as	as	SCONJ
elements-9064	167	83	compared	compare	VERB
elements-9064	167	84	to	to	PART
elements-9064	167	85	sivs	sivs	VERB
elements-9064	167	86	,	,	PUNCT
elements-9064	167	87	their	their	PRON
elements-9064	167	88	ubiquitous	ubiquitous	ADJ
elements-9064	167	89	presence	presence	NOUN
elements-9064	167	90	in	in	ADP
elements-9064	167	91	old	old	ADJ
elements-9064	167	92	world	world	NOUN
elements-9064	167	93	primates	primate	NOUN
elements-9064	167	94	,	,	PUNCT
elements-9064	167	95	and	and	CCONJ
elements-9064	167	96	the	the	DET
elements-9064	167	97	existence	existence	NOUN
elements-9064	167	98	of	of	ADP
elements-9064	167	99	an	an	DET
elements-9064	167	100	accessory	accessory	ADJ
elements-9064	167	101	protein	protein	NOUN
elements-9064	167	102	that	that	PRON
elements-9064	167	103	may	may	AUX
elements-9064	167	104	have	have	VERB
elements-9064	167	105	anti	anti	ADJ
elements-9064	167	106	-	-	ADJ
elements-9064	167	107	a3	a3	ADJ
elements-9064	167	108	properties	property	NOUN
elements-9064	167	109	together	together	ADV
elements-9064	167	110	suggest	suggest	VERB
elements-9064	167	111	that	that	SCONJ
elements-9064	167	112	sfvs	sfvs	PROPN
elements-9064	167	113	may	may	AUX
elements-9064	167	114	have	have	AUX
elements-9064	167	115	acted	act	VERB
elements-9064	167	116	as	as	ADP
elements-9064	167	117	a	a	DET
elements-9064	167	118	selective	selective	ADJ
elements-9064	167	119	pressure	pressure	NOUN
elements-9064	167	120	on	on	ADP
elements-9064	167	121	a3f	a3f	PROPN
elements-9064	167	122	.	.	PUNCT
elements-9064	168	1	this	this	DET
elements-9064	168	2	investigation	investigation	NOUN
elements-9064	168	3	offered	offer	VERB
elements-9064	168	4	valuable	valuable	ADJ
elements-9064	168	5	insight	insight	NOUN
elements-9064	168	6	into	into	ADP
elements-9064	168	7	the	the	DET
elements-9064	168	8	genetic	genetic	ADJ
elements-9064	168	9	diversity	diversity	NOUN
elements-9064	168	10	of	of	ADP
elements-9064	168	11	a3f	a3f	PROPN
elements-9064	168	12	in	in	ADP
elements-9064	168	13	old	old	ADJ
elements-9064	168	14	world	world	NOUN
elements-9064	168	15	primates	primate	NOUN
elements-9064	168	16	.	.	PUNCT
elements-9064	169	1	the	the	DET
elements-9064	169	2	presence	presence	NOUN
elements-9064	169	3	of	of	ADP
elements-9064	169	4	unusually	unusually	ADV
elements-9064	169	5	high	high	ADJ
elements-9064	169	6	intraand	intraand	NOUN
elements-9064	169	7	inter	inter	ADJ
elements-9064	169	8	-	-	ADJ
elements-9064	169	9	species	species	ADJ
elements-9064	169	10	variability	variability	NOUN
elements-9064	169	11	indicates	indicate	VERB
elements-9064	169	12	that	that	SCONJ
elements-9064	169	13	a3f	a3f	PROPN
elements-9064	169	14	has	have	AUX
elements-9064	169	15	been	be	AUX
elements-9064	169	16	continuously	continuously	ADV
elements-9064	169	17	exposed	expose	VERB
elements-9064	169	18	to	to	ADP
elements-9064	169	19	positive	positive	ADJ
elements-9064	169	20	selective	selective	ADJ
elements-9064	169	21	pressure	pressure	NOUN
elements-9064	169	22	.	.	PUNCT
elements-9064	170	1	while	while	SCONJ
elements-9064	170	2	siv	siv	PROPN
elements-9064	170	3	may	may	AUX
elements-9064	170	4	not	not	PART
elements-9064	170	5	necessarily	necessarily	ADV
elements-9064	170	6	be	be	AUX
elements-9064	170	7	the	the	DET
elements-9064	170	8	virus	virus	NOUN
elements-9064	170	9	responsible	responsible	ADJ
elements-9064	170	10	for	for	ADP
elements-9064	170	11	driving	drive	VERB
elements-9064	170	12	the	the	DET
elements-9064	170	13	polymorphism	polymorphism	NOUN
elements-9064	170	14	in	in	ADP
elements-9064	170	15	rhesus	rhesus	NOUN
elements-9064	170	16	macaque	macaque	ADJ
elements-9064	170	17	a3f	a3f	PROPN
elements-9064	170	18	,	,	PUNCT
elements-9064	170	19	understanding	understand	VERB
elements-9064	170	20	the	the	DET
elements-9064	170	21	restriction	restriction	NOUN
elements-9064	170	22	factor	factor	NOUN
elements-9064	170	23	’s	’s	PART
elements-9064	170	24	genetic	genetic	ADJ
elements-9064	170	25	variability	variability	NOUN
elements-9064	170	26	opens	open	VERB
elements-9064	170	27	a	a	DET
elements-9064	170	28	line	line	NOUN
elements-9064	170	29	of	of	ADP
elements-9064	170	30	inquiry	inquiry	NOUN
elements-9064	170	31	into	into	ADP
elements-9064	170	32	other	other	ADJ
elements-9064	170	33	potential	potential	ADJ
elements-9064	170	34	selective	selective	ADJ
elements-9064	170	35	pressures	pressure	NOUN
elements-9064	170	36	.	.	PUNCT
elements-9064	171	1	it	it	PRON
elements-9064	171	2	is	be	AUX
elements-9064	171	3	also	also	ADV
elements-9064	171	4	important	important	ADJ
elements-9064	171	5	to	to	PART
elements-9064	171	6	note	note	VERB
elements-9064	171	7	that	that	SCONJ
elements-9064	171	8	only	only	ADV
elements-9064	171	9	one	one	NUM
elements-9064	171	10	linked	link	VERB
elements-9064	171	11	polymorphic	polymorphic	ADJ
elements-9064	171	12	patch	patch	NOUN
elements-9064	171	13	was	be	AUX
elements-9064	171	14	investigated	investigate	VERB
elements-9064	171	15	;	;	PUNCT
elements-9064	171	16	there	there	PRON
elements-9064	171	17	are	be	VERB
elements-9064	171	18	several	several	ADJ
elements-9064	171	19	other	other	ADJ
elements-9064	171	20	sites	site	NOUN
elements-9064	171	21	that	that	PRON
elements-9064	171	22	may	may	AUX
elements-9064	171	23	play	play	VERB
elements-9064	171	24	a	a	DET
elements-9064	171	25	role	role	NOUN
elements-9064	171	26	in	in	ADP
elements-9064	171	27	interactions	interaction	NOUN
elements-9064	171	28	with	with	ADP
elements-9064	171	29	vif	vif	PROPN
elements-9064	171	30	.	.	PUNCT
elements-9064	172	1	further	further	ADJ
elements-9064	172	2	mutagenesis	mutagenesis	NOUN
elements-9064	172	3	studies	study	NOUN
elements-9064	172	4	will	will	AUX
elements-9064	172	5	reveal	reveal	VERB
elements-9064	172	6	whether	whether	SCONJ
elements-9064	172	7	any	any	PRON
elements-9064	172	8	of	of	ADP
elements-9064	172	9	these	these	DET
elements-9064	172	10	sites	site	NOUN
elements-9064	172	11	play	play	VERB
elements-9064	172	12	a	a	DET
elements-9064	172	13	role	role	NOUN
elements-9064	172	14	in	in	ADP
elements-9064	172	15	siv	siv	PROPN
elements-9064	172	16	restriction	restriction	NOUN
elements-9064	172	17	,	,	PUNCT
elements-9064	172	18	or	or	CCONJ
elements-9064	172	19	whether	whether	SCONJ
elements-9064	172	20	it	it	PRON
elements-9064	172	21	truly	truly	ADV
elements-9064	172	22	is	be	AUX
elements-9064	172	23	another	another	DET
elements-9064	172	24	virus	virus	NOUN
elements-9064	172	25	altogether	altogether	ADV
elements-9064	172	26	that	that	PRON
elements-9064	172	27	has	have	AUX
elements-9064	172	28	provided	provide	VERB
elements-9064	172	29	the	the	DET
elements-9064	172	30	selective	selective	ADJ
elements-9064	172	31	pressure	pressure	NOUN
elements-9064	172	32	on	on	ADP
elements-9064	172	33	rha3f	rha3f	PROPN
elements-9064	172	34	.	.	PUNCT
elements-9064	173	1	in	in	ADP
elements-9064	173	2	addition	addition	NOUN
elements-9064	173	3	,	,	PUNCT
elements-9064	173	4	the	the	DET
elements-9064	173	5	sooty	sooty	NOUN
elements-9064	173	6	mangabey	mangabey	PROPN
elements-9064	173	7	,	,	PUNCT
elements-9064	173	8	crabeating	crabeate	VERB
elements-9064	173	9	macaque	macaque	ADJ
elements-9064	173	10	,	,	PUNCT
elements-9064	173	11	and	and	CCONJ
elements-9064	173	12	pigtail	pigtail	ADJ
elements-9064	173	13	macaque	macaque	ADJ
elements-9064	173	14	a3f	a3f	PROPN
elements-9064	173	15	clones	clone	NOUN
elements-9064	173	16	have	have	AUX
elements-9064	173	17	not	not	PART
elements-9064	173	18	been	be	AUX
elements-9064	173	19	fully	fully	ADV
elements-9064	173	20	characterized	characterize	VERB
elements-9064	173	21	in	in	ADP
elements-9064	173	22	terms	term	NOUN
elements-9064	173	23	of	of	ADP
elements-9064	173	24	their	their	PRON
elements-9064	173	25	susceptibility	susceptibility	NOUN
elements-9064	173	26	to	to	ADP
elements-9064	173	27	various	various	ADJ
elements-9064	173	28	vifs	vif	NOUN
elements-9064	173	29	.	.	PUNCT
elements-9064	174	1	this	this	DET
elements-9064	174	2	information	information	NOUN
elements-9064	174	3	will	will	AUX
elements-9064	174	4	provide	provide	VERB
elements-9064	174	5	a	a	DET
elements-9064	174	6	more	more	ADV
elements-9064	174	7	complete	complete	ADJ
elements-9064	174	8	picture	picture	NOUN
elements-9064	174	9	of	of	ADP
elements-9064	174	10	the	the	DET
elements-9064	174	11	role	role	NOUN
elements-9064	174	12	that	that	PRON
elements-9064	174	13	vif	vif	PROPN
elements-9064	174	14	has	have	AUX
elements-9064	174	15	played	play	VERB
elements-9064	174	16	in	in	ADP
elements-9064	174	17	driving	drive	VERB
elements-9064	174	18	a3f	a3f	PROPN
elements-9064	174	19	evolution	evolution	NOUN
elements-9064	174	20	,	,	PUNCT
elements-9064	174	21	and	and	CCONJ
elements-9064	174	22	further	far	ADV
elements-9064	174	23	elucidate	elucidate	VERB
elements-9064	174	24	mechanisms	mechanism	NOUN
elements-9064	174	25	of	of	ADP
elements-9064	174	26	cross	cross	ADJ
elements-9064	174	27	-	-	ADJ
elements-9064	174	28	species	species	ADJ
elements-9064	174	29	transmission	transmission	NOUN
elements-9064	174	30	of	of	ADP
elements-9064	174	31	primate	primate	NOUN
elements-9064	174	32	lentiviruses	lentiviruse	NOUN
elements-9064	174	33	.	.	PUNCT
elements-9064	175	1	56	56	NUM
elements-9064	175	2	elements	element	NOUN
elements-9064	175	3	:	:	PUNCT
elements-9064	175	4	:	:	PUNCT
elements-9064	175	5	fall	fall	VERB
elements-9064	175	6	2015	2015	NUM
elements-9064	175	7	endnotes	endnote	NOUN
elements-9064	175	8	1	1	NUM
elements-9064	175	9	.	.	PUNCT
elements-9064	175	10	sharp	sharp	ADJ
elements-9064	175	11	and	and	CCONJ
elements-9064	175	12	hahn	hahn	PROPN
elements-9064	175	13	2008	2008	NUM
elements-9064	175	14	.	.	PUNCT
elements-9064	176	1	2	2	X
elements-9064	176	2	.	.	X
elements-9064	176	3	barre	barre	NOUN
elements-9064	176	4	-	-	PUNCT
elements-9064	176	5	sinoussi	sinoussi	NOUN
elements-9064	176	6	et	et	PROPN
elements-9064	176	7	al	al	PROPN
elements-9064	176	8	.	.	PROPN
elements-9064	176	9	,	,	PUNCT
elements-9064	176	10	1983	1983	NUM
elements-9064	176	11	.	.	PUNCT
elements-9064	177	1	3	3	X
elements-9064	177	2	.	.	X
elements-9064	177	3	gallo	gallo	PROPN
elements-9064	177	4	et	et	PROPN
elements-9064	177	5	al	al	PROPN
elements-9064	177	6	.	.	PROPN
elements-9064	177	7	,	,	PUNCT
elements-9064	177	8	1984	1984	NUM
elements-9064	177	9	.	.	PUNCT
elements-9064	178	1	4	4	NUM
elements-9064	178	2	.	.	PUNCT
elements-9064	178	3	huet	huet	PROPN
elements-9064	178	4	et	et	PROPN
elements-9064	178	5	al	al	PROPN
elements-9064	178	6	.	.	PROPN
elements-9064	178	7	,	,	PUNCT
elements-9064	178	8	1990	1990	NUM
elements-9064	178	9	.	.	PUNCT
elements-9064	179	1	5	5	NUM
elements-9064	179	2	.	.	X
elements-9064	179	3	hirsch	hirsch	PROPN
elements-9064	179	4	et	et	PROPN
elements-9064	179	5	al	al	PROPN
elements-9064	179	6	.	.	PROPN
elements-9064	179	7	,	,	PUNCT
elements-9064	179	8	1989	1989	NUM
elements-9064	179	9	.	.	PUNCT
elements-9064	180	1	6	6	NUM
elements-9064	180	2	.	.	NOUN
elements-9064	180	3	vandewoude	vandewoude	ADJ
elements-9064	180	4	and	and	CCONJ
elements-9064	180	5	apetrei	apetrei	ADJ
elements-9064	180	6	2006	2006	NUM
elements-9064	180	7	.	.	PUNCT
elements-9064	181	1	7	7	X
elements-9064	181	2	.	.	X
elements-9064	181	3	mccarthy	mccarthy	PROPN
elements-9064	181	4	and	and	CCONJ
elements-9064	181	5	johnson	johnson	PROPN
elements-9064	181	6	2014	2014	NUM
elements-9064	181	7	.	.	PUNCT
elements-9064	182	1	8	8	NUM
elements-9064	182	2	.	.	X
elements-9064	182	3	emerman	emerman	PROPN
elements-9064	182	4	and	and	CCONJ
elements-9064	182	5	malik	malik	PROPN
elements-9064	182	6	2010	2010	NUM
elements-9064	182	7	.	.	PUNCT
elements-9064	183	1	9	9	X
elements-9064	183	2	.	.	X
elements-9064	183	3	hurst	hurst	PROPN
elements-9064	183	4	2002	2002	NUM
elements-9064	183	5	.	.	PUNCT
elements-9064	184	1	10	10	NUM
elements-9064	184	2	.	.	X
elements-9064	184	3	meyerson	meyerson	NOUN
elements-9064	184	4	and	and	CCONJ
elements-9064	184	5	sawyer	sawyer	NOUN
elements-9064	184	6	2011	2011	NUM
elements-9064	184	7	.	.	PUNCT
elements-9064	185	1	11	11	NUM
elements-9064	185	2	.	.	X
elements-9064	186	1	harris	harris	PROPN
elements-9064	186	2	et	et	PROPN
elements-9064	186	3	al	al	PROPN
elements-9064	186	4	.	.	PROPN
elements-9064	186	5	,	,	PUNCT
elements-9064	186	6	2012	2012	NUM
elements-9064	186	7	.	.	PUNCT
elements-9064	187	1	12	12	NUM
elements-9064	187	2	.	.	PUNCT
elements-9064	188	1	koning	kone	VERB
elements-9064	188	2	et	et	PROPN
elements-9064	188	3	al	al	PROPN
elements-9064	188	4	.	.	PROPN
elements-9064	188	5	,	,	PUNCT
elements-9064	188	6	2009	2009	NUM
elements-9064	188	7	.	.	PUNCT
elements-9064	189	1	13	13	NUM
elements-9064	189	2	.	.	X
elements-9064	189	3	desimmie	desimmie	PROPN
elements-9064	189	4	et	et	PROPN
elements-9064	189	5	al	al	PROPN
elements-9064	189	6	.	.	PROPN
elements-9064	189	7	,	,	PUNCT
elements-9064	189	8	2014	2014	NUM
elements-9064	189	9	.	.	PUNCT
elements-9064	190	1	14	14	NUM
elements-9064	190	2	.	.	PUNCT
elements-9064	191	1	harris	harris	PROPN
elements-9064	191	2	et	et	PROPN
elements-9064	191	3	al	al	PROPN
elements-9064	191	4	.	.	PROPN
elements-9064	191	5	,	,	PUNCT
elements-9064	191	6	2012	2012	NUM
elements-9064	191	7	.	.	PUNCT
elements-9064	192	1	15	15	NUM
elements-9064	192	2	.	.	X
elements-9064	193	1	jarmuz	jarmuz	PROPN
elements-9064	193	2	et	et	PROPN
elements-9064	193	3	al	al	PROPN
elements-9064	193	4	.	.	PROPN
elements-9064	193	5	,	,	PUNCT
elements-9064	193	6	2002	2002	NUM
elements-9064	193	7	.	.	PUNCT
elements-9064	194	1	16	16	NUM
elements-9064	194	2	.	.	PUNCT
elements-9064	194	3	ibid	ibid	NOUN
elements-9064	194	4	..	..	PUNCT
elements-9064	195	1	17	17	NUM
elements-9064	195	2	.	.	PUNCT
elements-9064	195	3	desimmie	desimmie	PROPN
elements-9064	195	4	et	et	PROPN
elements-9064	195	5	al	al	PROPN
elements-9064	195	6	.	.	PROPN
elements-9064	195	7	,	,	PUNCT
elements-9064	195	8	2014	2014	NUM
elements-9064	195	9	.	.	PUNCT
elements-9064	196	1	18	18	NUM
elements-9064	196	2	.	.	PUNCT
elements-9064	197	1	bohn	bohn	PROPN
elements-9064	197	2	et	et	PROPN
elements-9064	197	3	al	al	PROPN
elements-9064	197	4	.	.	PROPN
elements-9064	197	5	,	,	PUNCT
elements-9064	197	6	2013	2013	NUM
elements-9064	197	7	.	.	PUNCT
elements-9064	198	1	19	19	NUM
elements-9064	198	2	.	.	X
elements-9064	198	3	desimmie	desimmie	PROPN
elements-9064	198	4	et	et	PROPN
elements-9064	198	5	al	al	PROPN
elements-9064	198	6	.	.	PROPN
elements-9064	198	7	,	,	PUNCT
elements-9064	198	8	2014	2014	NUM
elements-9064	198	9	.	.	PUNCT
elements-9064	199	1	20	20	NUM
elements-9064	199	2	.	.	X
elements-9064	199	3	mangeat	mangeat	PROPN
elements-9064	199	4	et	et	PROPN
elements-9064	199	5	al	al	PROPN
elements-9064	199	6	.	.	PROPN
elements-9064	199	7	,	,	PUNCT
elements-9064	199	8	2003	2003	NUM
elements-9064	199	9	.	.	PUNCT
elements-9064	200	1	21	21	NUM
elements-9064	200	2	.	.	PUNCT
elements-9064	200	3	bishop	bishop	PROPN
elements-9064	200	4	et	et	PROPN
elements-9064	200	5	al	al	PROPN
elements-9064	200	6	.	.	PROPN
elements-9064	200	7	,	,	PUNCT
elements-9064	200	8	2004	2004	NUM
elements-9064	200	9	.	.	PUNCT
elements-9064	201	1	22	22	NUM
elements-9064	201	2	.	.	PUNCT
elements-9064	201	3	wiegand	wiegand	NOUN
elements-9064	201	4	et	et	PROPN
elements-9064	201	5	al	al	PROPN
elements-9064	201	6	.	.	PROPN
elements-9064	201	7	,	,	PUNCT
elements-9064	201	8	2004	2004	NUM
elements-9064	201	9	.	.	PUNCT
elements-9064	202	1	23	23	NUM
elements-9064	202	2	.	.	PUNCT
elements-9064	202	3	harris	harris	PROPN
elements-9064	202	4	and	and	CCONJ
elements-9064	202	5	liddament	liddament	PROPN
elements-9064	202	6	2004	2004	NUM
elements-9064	202	7	.	.	PUNCT
elements-9064	203	1	24	24	NUM
elements-9064	203	2	.	.	PUNCT
elements-9064	203	3	sodroski	sodroski	VERB
elements-9064	203	4	et	et	PROPN
elements-9064	203	5	al	al	PROPN
elements-9064	203	6	.	.	PROPN
elements-9064	203	7	,	,	PUNCT
elements-9064	203	8	1986	1986	NUM
elements-9064	203	9	.	.	PUNCT
elements-9064	204	1	25	25	NUM
elements-9064	204	2	.	.	PUNCT
elements-9064	205	1	gabuzda	gabuzda	VERB
elements-9064	205	2	et	et	PROPN
elements-9064	205	3	al	al	PROPN
elements-9064	205	4	.	.	PROPN
elements-9064	205	5	,	,	PUNCT
elements-9064	205	6	1992	1992	NUM
elements-9064	205	7	.	.	PUNCT
elements-9064	206	1	26	26	NUM
elements-9064	206	2	.	.	PUNCT
elements-9064	207	1	sheehy	sheehy	PROPN
elements-9064	207	2	et	et	PROPN
elements-9064	207	3	al	al	PROPN
elements-9064	207	4	.	.	PROPN
elements-9064	207	5	,	,	PUNCT
elements-9064	207	6	2002	2002	NUM
elements-9064	207	7	.	.	PUNCT
elements-9064	208	1	27	27	NUM
elements-9064	208	2	.	.	PUNCT
elements-9064	209	1	marin	marin	NOUN
elements-9064	209	2	et	et	PROPN
elements-9064	209	3	al	al	PROPN
elements-9064	209	4	.	.	PROPN
elements-9064	209	5	,	,	PUNCT
elements-9064	209	6	2003	2003	NUM
elements-9064	209	7	.	.	PUNCT
elements-9064	210	1	28	28	NUM
elements-9064	210	2	.	.	PUNCT
elements-9064	211	1	sheehy	sheehy	PROPN
elements-9064	211	2	et	et	PROPN
elements-9064	211	3	al	al	PROPN
elements-9064	211	4	.	.	PROPN
elements-9064	211	5	,	,	PUNCT
elements-9064	211	6	2003	2003	NUM
elements-9064	211	7	.	.	PUNCT
elements-9064	212	1	29	29	NUM
elements-9064	212	2	.	.	PUNCT
elements-9064	213	1	simon	simon	PROPN
elements-9064	213	2	et	et	PROPN
elements-9064	213	3	al	al	PROPN
elements-9064	213	4	.	.	PROPN
elements-9064	213	5	,	,	PUNCT
elements-9064	213	6	1998	1998	NUM
elements-9064	213	7	.	.	PUNCT
elements-9064	214	1	30	30	NUM
elements-9064	214	2	.	.	PUNCT
elements-9064	215	1	holmes	holmes	PROPN
elements-9064	215	2	et	et	PROPN
elements-9064	215	3	al	al	PROPN
elements-9064	215	4	.	.	PROPN
elements-9064	215	5	,	,	PUNCT
elements-9064	215	6	2007	2007	NUM
elements-9064	215	7	.	.	PUNCT
elements-9064	216	1	31	31	NUM
elements-9064	216	2	.	.	PUNCT
elements-9064	217	1	bogerd	bogerd	PROPN
elements-9064	217	2	et	et	PROPN
elements-9064	217	3	al	al	PROPN
elements-9064	217	4	.	.	PROPN
elements-9064	217	5	,	,	PUNCT
elements-9064	217	6	2004	2004	NUM
elements-9064	217	7	.	.	PUNCT
elements-9064	218	1	32	32	NUM
elements-9064	218	2	.	.	PUNCT
elements-9064	218	3	huthoff	huthoff	NOUN
elements-9064	218	4	and	and	CCONJ
elements-9064	218	5	malim	malim	NOUN
elements-9064	218	6	2007	2007	NUM
elements-9064	218	7	.	.	PUNCT
elements-9064	219	1	33	33	NUM
elements-9064	219	2	.	.	PUNCT
elements-9064	219	3	smith	smith	PROPN
elements-9064	219	4	and	and	CCONJ
elements-9064	219	5	pathak	pathak	PROPN
elements-9064	219	6	2010	2010	NUM
elements-9064	219	7	.	.	PUNCT
elements-9064	220	1	34	34	NUM
elements-9064	220	2	.	.	PUNCT
elements-9064	220	3	albin	albin	PROPN
elements-9064	220	4	et	et	PROPN
elements-9064	220	5	al	al	PROPN
elements-9064	220	6	.	.	PROPN
elements-9064	220	7	,	,	PUNCT
elements-9064	220	8	2010	2010	NUM
elements-9064	220	9	.	.	PUNCT
elements-9064	221	1	35	35	NUM
elements-9064	221	2	.	.	PUNCT
elements-9064	221	3	land	land	NOUN
elements-9064	221	4	et	et	PROPN
elements-9064	221	5	al	al	PROPN
elements-9064	221	6	.	.	PROPN
elements-9064	221	7	,	,	PUNCT
elements-9064	221	8	2014	2014	NUM
elements-9064	221	9	.	.	PUNCT
elements-9064	222	1	36	36	NUM
elements-9064	222	2	.	.	PUNCT
elements-9064	223	1	he	he	PRON
elements-9064	223	2	et	et	PROPN
elements-9064	223	3	al	al	PROPN
elements-9064	223	4	.	.	PROPN
elements-9064	223	5	,	,	PUNCT
elements-9064	223	6	2008	2008	NUM
elements-9064	223	7	.	.	PUNCT
elements-9064	224	1	37	37	NUM
elements-9064	224	2	.	.	PUNCT
elements-9064	225	1	russell	russell	PROPN
elements-9064	225	2	and	and	CCONJ
elements-9064	225	3	pathak	pathak	PROPN
elements-9064	225	4	2007	2007	NUM
elements-9064	225	5	.	.	PUNCT
elements-9064	226	1	38	38	NUM
elements-9064	226	2	.	.	PUNCT
elements-9064	227	1	hatziioannou	hatziioannou	NOUN
elements-9064	227	2	and	and	CCONJ
elements-9064	227	3	evans	evans	PROPN
elements-9064	227	4	2012	2012	NUM
elements-9064	227	5	.	.	PUNCT
elements-9064	228	1	39	39	NUM
elements-9064	228	2	.	.	PUNCT
elements-9064	229	1	apetrei	apetrei	ADV
elements-9064	229	2	et	et	PROPN
elements-9064	229	3	al	al	PROPN
elements-9064	229	4	.	.	PROPN
elements-9064	229	5	,	,	PUNCT
elements-9064	229	6	2005	2005	NUM
elements-9064	229	7	.	.	PUNCT
elements-9064	230	1	40	40	NUM
elements-9064	230	2	.	.	PUNCT
elements-9064	231	1	mansfield	mansfield	PROPN
elements-9064	231	2	et	et	PROPN
elements-9064	231	3	al	al	PROPN
elements-9064	231	4	.	.	PROPN
elements-9064	231	5	,	,	PUNCT
elements-9064	231	6	1995	1995	NUM
elements-9064	231	7	.	.	PUNCT
elements-9064	232	1	41	41	NUM
elements-9064	232	2	.	.	PUNCT
elements-9064	233	1	marx	marx	PROPN
elements-9064	233	2	et	et	PROPN
elements-9064	233	3	al	al	PROPN
elements-9064	233	4	.	.	PROPN
elements-9064	233	5	,	,	PUNCT
elements-9064	233	6	2004	2004	NUM
elements-9064	233	7	.	.	PUNCT
elements-9064	234	1	42	42	NUM
elements-9064	234	2	.	.	PUNCT
elements-9064	235	1	krupp	krupp	PROPN
elements-9064	235	2	et	et	PROPN
elements-9064	235	3	al	al	PROPN
elements-9064	235	4	.	.	PROPN
elements-9064	235	5	,	,	PUNCT
elements-9064	235	6	2013	2013	NUM
elements-9064	235	7	.	.	PUNCT
elements-9064	236	1	43	43	NUM
elements-9064	236	2	.	.	PUNCT
elements-9064	237	1	sawyer	sawyer	PROPN
elements-9064	237	2	et	et	PROPN
elements-9064	237	3	al	al	PROPN
elements-9064	237	4	.	.	PROPN
elements-9064	237	5	,	,	PUNCT
elements-9064	237	6	2004	2004	NUM
elements-9064	237	7	.	.	PUNCT
elements-9064	238	1	44	44	NUM
elements-9064	238	2	.	.	PUNCT
elements-9064	239	1	delport	delport	NOUN
elements-9064	239	2	et	et	PROPN
elements-9064	239	3	al	al	PROPN
elements-9064	239	4	.	.	PROPN
elements-9064	239	5	,	,	PUNCT
elements-9064	239	6	2010	2010	NUM
elements-9064	239	7	.	.	PUNCT
elements-9064	240	1	45	45	NUM
elements-9064	240	2	.	.	PUNCT
elements-9064	240	3	kosakovsky	kosakovsky	PROPN
elements-9064	240	4	pond	pond	NOUN
elements-9064	240	5	and	and	CCONJ
elements-9064	240	6	frost	frost	NOUN
elements-9064	240	7	2005a	2005a	NUM
elements-9064	240	8	.	.	PUNCT
elements-9064	241	1	46	46	NUM
elements-9064	241	2	.	.	PUNCT
elements-9064	241	3	kosakovsky	kosakovsky	PROPN
elements-9064	241	4	pond	pond	PROPN
elements-9064	241	5	et	et	PROPN
elements-9064	241	6	al	al	PROPN
elements-9064	241	7	.	.	PROPN
elements-9064	241	8	,	,	PUNCT
elements-9064	241	9	2005	2005	NUM
elements-9064	241	10	.	.	PUNCT
elements-9064	242	1	47	47	NUM
elements-9064	242	2	.	.	PUNCT
elements-9064	242	3	kosakovsky	kosakovsky	PROPN
elements-9064	242	4	pond	pond	NOUN
elements-9064	242	5	and	and	CCONJ
elements-9064	242	6	frost	frost	NOUN
elements-9064	242	7	2005b	2005b	NUM
elements-9064	242	8	.	.	PUNCT
elements-9064	243	1	48	48	NUM
elements-9064	243	2	.	.	PUNCT
elements-9064	244	1	krupp	krupp	PROPN
elements-9064	244	2	et	et	PROPN
elements-9064	244	3	al	al	PROPN
elements-9064	244	4	.	.	PROPN
elements-9064	244	5	,	,	PUNCT
elements-9064	244	6	2013	2013	NUM
elements-9064	244	7	.	.	PUNCT
elements-9064	245	1	49	49	NUM
elements-9064	245	2	.	.	PUNCT
elements-9064	246	1	ibid	ibid	NOUN
elements-9064	246	2	..	..	PUNCT
elements-9064	247	1	50	50	NUM
elements-9064	247	2	.	.	PUNCT
elements-9064	247	3	murray	murray	NOUN
elements-9064	247	4	and	and	CCONJ
elements-9064	247	5	linial	linial	ADJ
elements-9064	247	6	2006	2006	NUM
elements-9064	247	7	.	.	PUNCT
elements-9064	248	1	51	51	NUM
elements-9064	248	2	.	.	PUNCT
elements-9064	249	1	meiering	meiering	NOUN
elements-9064	249	2	and	and	CCONJ
elements-9064	249	3	linial	linial	ADJ
elements-9064	249	4	2001	2001	NUM
elements-9064	249	5	.	.	PUNCT
elements-9064	250	1	52	52	NUM
elements-9064	250	2	.	.	PUNCT
elements-9064	251	1	switzer	switzer	PROPN
elements-9064	251	2	et	et	PROPN
elements-9064	251	3	al	al	PROPN
elements-9064	251	4	.	.	PROPN
elements-9064	251	5	,	,	PUNCT
elements-9064	251	6	2004	2004	NUM
elements-9064	251	7	.	.	PUNCT
elements-9064	252	1	53	53	NUM
elements-9064	252	2	.	.	PUNCT
elements-9064	253	1	russell	russell	PROPN
elements-9064	253	2	et	et	PROPN
elements-9064	253	3	al	al	PROPN
elements-9064	253	4	.	.	PROPN
elements-9064	253	5	,	,	PUNCT
elements-9064	253	6	2005	2005	NUM
elements-9064	253	7	.	.	PUNCT
elements-9064	254	1	54	54	NUM
elements-9064	254	2	.	.	X
elements-9064	254	3	lochelt	lochelt	VERB
elements-9064	254	4	et	et	PROPN
elements-9064	254	5	al	al	PROPN
elements-9064	254	6	.	.	PROPN
elements-9064	254	7	,	,	PUNCT
elements-9064	254	8	2005	2005	NUM
elements-9064	254	9	.	.	PUNCT
elements-9064	255	1	references	reference	NOUN
elements-9064	255	2	albin	albin	PROPN
elements-9064	255	3	,	,	PUNCT
elements-9064	255	4	j.	j.	PROPN
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elements-9064	255	6	,	,	PUNCT
elements-9064	255	7	r.	r.	PROPN
elements-9064	255	8	s.	s.	PROPN
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elements-9064	255	10	,	,	PUNCT
elements-9064	255	11	j.	j.	PROPN
elements-9064	255	12	a.	a.	PROPN
elements-9064	255	13	weaver	weaver	PROPN
elements-9064	255	14	,	,	PUNCT
elements-9064	255	15	w.	w.	PROPN
elements-9064	255	16	l.	l.	PROPN
elements-9064	255	17	brown	brown	PROPN
elements-9064	255	18	,	,	PUNCT
elements-9064	255	19	k.	k.	PROPN
elements-9064	255	20	shindo	shindo	PROPN
elements-9064	255	21	,	,	PUNCT
elements-9064	255	22	e.	e.	PROPN
elements-9064	255	23	harjes	harjes	PROPN
elements-9064	255	24	,	,	PUNCT
elements-9064	255	25	h.	h.	PROPN
elements-9064	255	26	matsuo	matsuo	PROPN
elements-9064	255	27	,	,	PUNCT
elements-9064	255	28	and	and	CCONJ
elements-9064	255	29	r.	r.	PROPN
elements-9064	255	30	s.	s.	PROPN
elements-9064	255	31	harris	harris	PROPN
elements-9064	255	32	.	.	PUNCT
elements-9064	255	33	2010	2010	NUM
elements-9064	255	34	.	.	PUNCT
elements-9064	256	1	“	"	PUNCT
elements-9064	256	2	a	a	DET
elements-9064	256	3	single	single	ADJ
elements-9064	256	4	amino	amino	NOUN
elements-9064	256	5	acid	acid	NOUN
elements-9064	256	6	in	in	ADP
elements-9064	256	7	human	human	ADJ
elements-9064	256	8	apobec3f	apobec3f	PROPN
elements-9064	256	9	alters	alter	VERB
elements-9064	256	10	susceptibility	susceptibility	NOUN
elements-9064	256	11	to	to	ADP
elements-9064	256	12	hiv-1	hiv-1	X
elements-9064	256	13	vif	vif	PROPN
elements-9064	256	14	.	.	PUNCT
elements-9064	256	15	”	"	PUNCT
elements-9064	256	16	 	 	SPACE
elements-9064	256	17	the	the	DET
elements-9064	256	18	journal	journal	NOUN
elements-9064	256	19	of	of	ADP
elements-9064	256	20	biological	biological	ADJ
elements-9064	256	21	chemistry	chemistry	NOUN
elements-9064	256	22	285	285	NUM
elements-9064	256	23	(	(	PUNCT
elements-9064	256	24	52	52	NUM
elements-9064	256	25	):	):	SYM
elements-9064	256	26	40785	40785	NUM
elements-9064	256	27	-	-	SYM
elements-9064	256	28	40792	40792	NUM
elements-9064	256	29	.	.	PUNCT
elements-9064	257	1	doi	doi	NOUN
elements-9064	257	2	:	:	PUNCT
elements-9064	257	3	10.1074	10.1074	NUM
elements-9064	257	4	/	/	SYM
elements-9064	257	5	jbc.m110.173161	jbc.m110.173161	ADJ
elements-9064	257	6	.	.	PUNCT
elements-9064	257	7	alce	alce	PROPN
elements-9064	257	8	,	,	PUNCT
elements-9064	257	9	t.	t.	PROPN
elements-9064	257	10	m.	m.	NOUN
elements-9064	257	11	and	and	CCONJ
elements-9064	257	12	w.	w.	PROPN
elements-9064	257	13	popik	popik	PROPN
elements-9064	257	14	.	.	PUNCT
elements-9064	258	1	2004	2004	NUM
elements-9064	258	2	.	.	PUNCT
elements-9064	259	1	“	"	PUNCT
elements-9064	259	2	apobec3	apobec3	PROPN
elements-9064	259	3	g	g	PROPN
elements-9064	259	4	is	be	AUX
elements-9064	259	5	incorporated	incorporate	VERB
elements-9064	259	6	into	into	ADP
elements-9064	259	7	virus	virus	NOUN
elements-9064	259	8	-	-	PUNCT
elements-9064	259	9	like	like	ADJ
elements-9064	259	10	particles	particle	NOUN
elements-9064	259	11	by	by	ADP
elements-9064	259	12	a	a	DET
elements-9064	259	13	direct	direct	ADJ
elements-9064	259	14	interaction	interaction	NOUN
elements-9064	259	15	with	with	ADP
elements-9064	259	16	hiv-1	hiv-1	PUNCT
elements-9064	259	17	gag	gag	ADJ
elements-9064	259	18	nucleocapsid	nucleocapsid	ADJ
elements-9064	259	19	protein	protein	NOUN
elements-9064	259	20	.	.	PUNCT
elements-9064	259	21	”	"	PUNCT
elements-9064	259	22	 	 	SPACE
elements-9064	259	23	the	the	DET
elements-9064	259	24	journal	journal	NOUN
elements-9064	259	25	of	of	ADP
elements-9064	259	26	biological	biological	ADJ
elements-9064	259	27	chemistry	chemistry	NOUN
elements-9064	259	28	279	279	NUM
elements-9064	259	29	(	(	PUNCT
elements-9064	259	30	33	33	NUM
elements-9064	259	31	):	):	PUNCT
elements-9064	259	32	34083	34083	NUM
elements-9064	259	33	-	-	SYM
elements-9064	259	34	34086	34086	NUM
elements-9064	259	35	.	.	PUNCT
elements-9064	260	1	doi	doi	NOUN
elements-9064	260	2	:	:	PUNCT
elements-9064	260	3	10.1074	10.1074	NUM
elements-9064	260	4	/	/	SYM
elements-9064	260	5	jbc	jbc	PROPN
elements-9064	260	6	.	.	PUNCT
elements-9064	261	1	c40023520	c40023520	NOUN
elements-9064	261	2	.	.	PUNCT
elements-9064	262	1	apetrei	apetrei	PROPN
elements-9064	262	2	,	,	PUNCT
elements-9064	262	3	c.	c.	PROPN
elements-9064	262	4	,	,	PUNCT
elements-9064	262	5	a.	a.	PROPN
elements-9064	262	6	kaur	kaur	PROPN
elements-9064	262	7	,	,	PUNCT
elements-9064	262	8	n.	n.	PROPN
elements-9064	262	9	w.	w.	PROPN
elements-9064	262	10	lerche	lerche	PROPN
elements-9064	262	11	,	,	PUNCT
elements-9064	262	12	m.	m.	NOUN
elements-9064	262	13	metzger	metzger	PROPN
elements-9064	262	14	,	,	PUNCT
elements-9064	262	15	i.	i.	PROPN
elements-9064	262	16	pandrea	pandrea	PROPN
elements-9064	262	17	,	,	PUNCT
elements-9064	262	18	j.	j.	PROPN
elements-9064	262	19	hardcastle	hardcastle	PROPN
elements-9064	262	20	,	,	PUNCT
elements-9064	262	21	s.	s.	PROPN
elements-9064	262	22	falkenstein	falkenstein	PROPN
elements-9064	262	23	,	,	PUNCT
elements-9064	262	24	et	et	PROPN
elements-9064	262	25	al	al	PROPN
elements-9064	262	26	.	.	PROPN
elements-9064	262	27	2005	2005	NUM
elements-9064	262	28	.	.	PUNCT
elements-9064	263	1	“	"	PUNCT
elements-9064	263	2	molecular	molecular	ADJ
elements-9064	263	3	epidemiology	epidemiology	NOUN
elements-9064	263	4	of	of	ADP
elements-9064	263	5	simian	simian	ADJ
elements-9064	263	6	immunodeficiency	immunodeficiency	NOUN
elements-9064	263	7	virus	virus	NOUN
elements-9064	263	8	sivsm	sivsm	NOUN
elements-9064	263	9	in	in	ADP
elements-9064	263	10	u.s	u.s	PROPN
elements-9064	263	11	.	.	PROPN
elements-9064	263	12	primate	primate	PROPN
elements-9064	263	13	centers	center	NOUN
elements-9064	263	14	unravels	unravel	VERB
elements-9064	263	15	the	the	DET
elements-9064	263	16	origin	origin	NOUN
elements-9064	263	17	of	of	ADP
elements-9064	263	18	sivmac	sivmac	PROPN
elements-9064	263	19	and	and	CCONJ
elements-9064	263	20	sivstm	sivstm	NOUN
elements-9064	263	21	.	.	PUNCT
elements-9064	263	22	”	"	PUNCT
elements-9064	263	23	  	  	SPACE
elements-9064	263	24	journal	journal	NOUN
elements-9064	263	25	of	of	ADP
elements-9064	263	26	virology	virology	NOUN
elements-9064	263	27	  	  	SPACE
elements-9064	263	28	79	79	NUM
elements-9064	263	29	(	(	PUNCT
elements-9064	263	30	14	14	NUM
elements-9064	263	31	):	):	PUNCT
elements-9064	263	32	8991	8991	NUM
elements-9064	263	33	-	-	SYM
elements-9064	263	34	9005	9005	NUM
elements-9064	263	35	.	.	PUNCT
elements-9064	264	1	doi	doi	NOUN
elements-9064	264	2	:	:	PUNCT
elements-9064	264	3	10.1128	10.1128	NUM
elements-9064	264	4	/	/	SYM
elements-9064	264	5	jvi.79.14.8991	jvi.79.14.8991	NOUN
elements-9064	264	6	-	-	PUNCT
elements-9064	264	7	9005.2005	9005.2005	PROPN
elements-9064	264	8	.	.	PUNCT
elements-9064	265	1	barre	barre	PROPN
elements-9064	265	2	-	-	PUNCT
elements-9064	265	3	sinoussi	sinoussi	NOUN
elements-9064	265	4	,	,	PUNCT
elements-9064	265	5	f.	f.	PROPN
elements-9064	265	6	,	,	PUNCT
elements-9064	265	7	j.	j.	PROPN
elements-9064	265	8	c.	c.	PROPN
elements-9064	265	9	chermann	chermann	PROPN
elements-9064	265	10	,	,	PUNCT
elements-9064	265	11	f.	f.	PROPN
elements-9064	265	12	rey	rey	PROPN
elements-9064	265	13	,	,	PUNCT
elements-9064	265	14	m.	m.	NOUN
elements-9064	265	15	t.	t.	PROPN
elements-9064	265	16	nugeyre	nugeyre	PROPN
elements-9064	265	17	,	,	PUNCT
elements-9064	265	18	s.	s.	PROPN
elements-9064	265	19	chamaret	chamaret	PROPN
elements-9064	265	20	,	,	PUNCT
elements-9064	265	21	j.	j.	PROPN
elements-9064	265	22	gruest	gruest	PROPN
elements-9064	265	23	,	,	PUNCT
elements-9064	265	24	c.	c.	PROPN
elements-9064	265	25	dauguet	dauguet	PROPN
elements-9064	265	26	,	,	PUNCT
elements-9064	265	27	et	et	PROPN
elements-9064	265	28	al	al	PROPN
elements-9064	265	29	.	.	PROPN
elements-9064	265	30	1983	1983	NUM
elements-9064	265	31	.	.	PUNCT
elements-9064	266	1	“	"	PUNCT
elements-9064	266	2	isolation	isolation	NOUN
elements-9064	266	3	of	of	ADP
elements-9064	266	4	a	a	DET
elements-9064	266	5	t	t	NOUN
elements-9064	266	6	-	-	PUNCT
elements-9064	266	7	lymphotropic	lymphotropic	NOUN
elements-9064	266	8	retrovirus	retrovirus	NOUN
elements-9064	266	9	from	from	ADP
elements-9064	266	10	a	a	DET
elements-9064	266	11	patient	patient	NOUN
elements-9064	266	12	at	at	ADP
elements-9064	266	13	risk	risk	NOUN
elements-9064	266	14	for	for	ADP
elements-9064	266	15	acquired	acquire	VERB
elements-9064	266	16	immune	immune	ADJ
elements-9064	266	17	deficiency	deficiency	NOUN
elements-9064	266	18	syndrome	syndrome	NOUN
elements-9064	266	19	(	(	PUNCT
elements-9064	266	20	aids	aids	PROPN
elements-9064	266	21	)	)	PUNCT
elements-9064	266	22	.	.	PUNCT
elements-9064	266	23	”	"	PUNCT
elements-9064	266	24	 	 	SPACE
elements-9064	267	1	science	science	NOUN
elements-9064	267	2	(	(	PUNCT
elements-9064	267	3	new	new	PROPN
elements-9064	267	4	york	york	PROPN
elements-9064	267	5	,	,	PUNCT
elements-9064	267	6	n.y	n.y	PROPN
elements-9064	267	7	.	.	PROPN
elements-9064	267	8	)	)	PUNCT
elements-9064	267	9	 	 	SPACE
elements-9064	267	10	220	220	NUM
elements-9064	267	11	(	(	PUNCT
elements-9064	267	12	4599	4599	NUM
elements-9064	267	13	):	):	PUNCT
elements-9064	267	14	868	868	NUM
elements-9064	267	15	-	-	SYM
elements-9064	267	16	871	871	NUM
elements-9064	267	17	.	.	PUNCT
elements-9064	268	1	bishop	bishop	PROPN
elements-9064	268	2	,	,	PUNCT
elements-9064	268	3	k.	k.	PROPN
elements-9064	268	4	n.	n.	PROPN
elements-9064	268	5	,	,	PUNCT
elements-9064	268	6	r.	r.	PROPN
elements-9064	268	7	k.	k.	PROPN
elements-9064	268	8	holmes	holmes	PROPN
elements-9064	268	9	,	,	PUNCT
elements-9064	268	10	a.	a.	PROPN
elements-9064	268	11	m.	m.	PROPN
elements-9064	268	12	sheehy	sheehy	PROPN
elements-9064	268	13	,	,	PUNCT
elements-9064	268	14	n.	n.	PROPN
elements-9064	268	15	o.	o.	PROPN
elements-9064	268	16	davidson	davidson	PROPN
elements-9064	268	17	,	,	PUNCT
elements-9064	268	18	s.	s.	PROPN
elements-9064	268	19	j.	j.	PROPN
elements-9064	268	20	cho	cho	PROPN
elements-9064	268	21	,	,	PUNCT
elements-9064	268	22	and	and	CCONJ
elements-9064	268	23	m.	m.	PROPN
elements-9064	268	24	h.	h.	PROPN
elements-9064	268	25	malim	malim	PROPN
elements-9064	268	26	.	.	PUNCT
elements-9064	269	1	2004	2004	NUM
elements-9064	269	2	.	.	PUNCT
elements-9064	270	1	“	"	PUNCT
elements-9064	270	2	cytidine	cytidine	NOUN
elements-9064	270	3	deamination	deamination	NOUN
elements-9064	270	4	of	of	ADP
elements-9064	270	5	retroviral	retroviral	ADJ
elements-9064	270	6	dna	dna	NOUN
elements-9064	270	7	by	by	ADP
elements-9064	270	8	diverse	diverse	ADJ
elements-9064	270	9	apobec	apobec	NOUN
elements-9064	270	10	proteins	protein	NOUN
elements-9064	270	11	.	.	PUNCT
elements-9064	270	12	”	"	PUNCT
elements-9064	270	13	 	 	SPACE
elements-9064	270	14	current	current	ADJ
elements-9064	270	15	biology	biology	NOUN
elements-9064	270	16	:	:	PUNCT
elements-9064	270	17	cb	cb	PROPN
elements-9064	270	18	 	 	SPACE
elements-9064	270	19	14	14	NUM
elements-9064	270	20	(	(	PUNCT
elements-9064	270	21	15	15	NUM
elements-9064	270	22	):	):	PUNCT
elements-9064	270	23	1392	1392	NUM
elements-9064	270	24	-	-	SYM
elements-9064	270	25	1396	1396	NUM
elements-9064	270	26	.	.	PUNCT
elements-9064	271	1	doi	doi	NOUN
elements-9064	271	2	:	:	PUNCT
elements-9064	271	3	10.1016	10.1016	NUM
elements-9064	271	4	/	/	SYM
elements-9064	271	5	j.	j.	PROPN
elements-9064	271	6	cub.2004.06.057	cub.2004.06.057	PROPN
elements-9064	271	7	.	.	PUNCT
elements-9064	272	1	bogerd	bogerd	PROPN
elements-9064	272	2	,	,	PUNCT
elements-9064	272	3	h.	h.	PROPN
elements-9064	272	4	p.	p.	PROPN
elements-9064	272	5	,	,	PUNCT
elements-9064	272	6	b.	b.	PROPN
elements-9064	272	7	p.	p.	PROPN
elements-9064	272	8	doehle	doehle	PROPN
elements-9064	272	9	,	,	PUNCT
elements-9064	272	10	h.	h.	PROPN
elements-9064	272	11	l.	l.	PROPN
elements-9064	272	12	wiegand	wiegand	PROPN
elements-9064	272	13	,	,	PUNCT
elements-9064	272	14	and	and	CCONJ
elements-9064	272	15	b.	b.	PROPN
elements-9064	272	16	r.	r.	PROPN
elements-9064	272	17	cullen	cullen	PROPN
elements-9064	272	18	.	.	PUNCT
elements-9064	273	1	2004	2004	NUM
elements-9064	273	2	.	.	PUNCT
elements-9064	274	1	“	"	PUNCT
elements-9064	274	2	a	a	DET
elements-9064	274	3	single	single	ADJ
elements-9064	274	4	amino	amino	NOUN
elements-9064	274	5	acid	acid	NOUN
elements-9064	274	6	difference	difference	NOUN
elements-9064	274	7	in	in	ADP
elements-9064	274	8	the	the	DET
elements-9064	274	9	host	host	NOUN
elements-9064	274	10	apobec3	apobec3	ADP
elements-9064	274	11	g	g	NOUN
elements-9064	274	12	protein	protein	NOUN
elements-9064	274	13	controls	control	VERB
elements-9064	274	14	the	the	DET
elements-9064	274	15	primate	primate	NOUN
elements-9064	274	16	species	species	NOUN
elements-9064	274	17	specificity	specificity	NOUN
elements-9064	274	18	of	of	ADP
elements-9064	274	19	hiv	hiv	PROPN
elements-9064	274	20	type	type	NOUN
elements-9064	274	21	1	1	NUM
elements-9064	274	22	virion	virion	NOUN
elements-9064	274	23	infectivity	infectivity	NOUN
elements-9064	274	24	factor	factor	NOUN
elements-9064	274	25	.	.	PUNCT
elements-9064	274	26	”	"	PUNCT
elements-9064	274	27	 	 	SPACE
elements-9064	274	28	proceedings	proceeding	NOUN
elements-9064	274	29	of	of	ADP
elements-9064	274	30	the	the	DET
elements-9064	274	31	national	national	PROPN
elements-9064	274	32	academy	academy	PROPN
elements-9064	274	33	of	of	ADP
elements-9064	274	34	sciences	sciences	PROPN
elements-9064	274	35	of	of	ADP
elements-9064	274	36	the	the	DET
elements-9064	274	37	united	united	PROPN
elements-9064	274	38	states	states	PROPN
elements-9064	274	39	of	of	ADP
elements-9064	274	40	america	america	PROPN
elements-9064	274	41	 	 	SPACE
elements-9064	274	42	101	101	NUM
elements-9064	274	43	(	(	PUNCT
elements-9064	274	44	11	11	NUM
elements-9064	274	45	):	):	PUNCT
elements-9064	274	46	3770	3770	NUM
elements-9064	274	47	-	-	SYM
elements-9064	274	48	3774	3774	NUM
elements-9064	274	49	.	.	PUNCT
elements-9064	275	1	doi	doi	NOUN
elements-9064	275	2	:	:	PUNCT
elements-9064	275	3	10.1073	10.1073	NUM
elements-9064	275	4	/	/	SYM
elements-9064	275	5	pnas.0307713101	pnas.0307713101	PROPN
elements-9064	275	6	.	.	PUNCT
elements-9064	276	1	bohn	bohn	PROPN
elements-9064	276	2	,	,	PUNCT
elements-9064	276	3	m.	m.	PROPN
elements-9064	276	4	f.	f.	PROPN
elements-9064	276	5	,	,	PUNCT
elements-9064	276	6	s.	s.	PROPN
elements-9064	276	7	m.	m.	PROPN
elements-9064	276	8	shandilya	shandilya	PROPN
elements-9064	276	9	,	,	PUNCT
elements-9064	276	10	j.	j.	PROPN
elements-9064	276	11	s.	s.	PROPN
elements-9064	276	12	albin	albin	PROPN
elements-9064	276	13	,	,	PUNCT
elements-9064	276	14	t.	t.	PROPN
elements-9064	276	15	kouno	kouno	PROPN
elements-9064	276	16	,	,	PUNCT
elements-9064	276	17	b.	b.	PROPN
elements-9064	276	18	d.	d.	PROPN
elements-9064	276	19	anderson	anderson	PROPN
elements-9064	276	20	,	,	PUNCT
elements-9064	276	21	r.	r.	PROPN
elements-9064	276	22	m.	m.	PROPN
elements-9064	276	23	mcdougle	mcdougle	PROPN
elements-9064	276	24	,	,	PUNCT
elements-9064	276	25	m.	m.	NOUN
elements-9064	276	26	a.	a.	NOUN
elements-9064	276	27	carpenter	carpenter	PROPN
elements-9064	276	28	,	,	PUNCT
elements-9064	276	29	et	et	PROPN
elements-9064	276	30	al	al	PROPN
elements-9064	276	31	.	.	PROPN
elements-9064	276	32	2013	2013	NUM
elements-9064	276	33	.	.	PUNCT
elements-9064	277	1	“	"	PUNCT
elements-9064	277	2	crystal	crystal	NOUN
elements-9064	277	3	structure	structure	NOUN
elements-9064	277	4	of	of	ADP
elements-9064	277	5	the	the	DET
elements-9064	277	6	dna	dna	PROPN
elements-9064	277	7	cytosine	cytosine	NOUN
elements-9064	277	8	deaminase	deaminase	NOUN
elements-9064	277	9	apobec3f	apobec3f	PROPN
elements-9064	277	10	:	:	PUNCT
elements-9064	277	11	the	the	DET
elements-9064	277	12	catalytically	catalytically	ADV
elements-9064	277	13	active	active	ADJ
elements-9064	277	14	and	and	CCONJ
elements-9064	277	15	hiv-1	hiv-1	PUNCT
elements-9064	277	16	vif	vif	NOUN
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elements-9064	277	18	binding	binding	ADJ
elements-9064	277	19	domain	domain	NOUN
elements-9064	277	20	.	.	PUNCT
elements-9064	277	21	”	"	PUNCT
elements-9064	277	22	  	  	SPACE
elements-9064	277	23	structure	structure	NOUN
elements-9064	277	24	(	(	PUNCT
elements-9064	277	25	london	london	PROPN
elements-9064	277	26	,	,	PUNCT
elements-9064	277	27	england	england	PROPN
elements-9064	277	28	:	:	PUNCT
elements-9064	277	29	1993	1993	NUM
elements-9064	277	30	)	)	PUNCT
elements-9064	277	31	  	  	SPACE
elements-9064	277	32	21	21	NUM
elements-9064	277	33	(	(	PUNCT
elements-9064	277	34	6	6	NUM
elements-9064	277	35	):	):	SYM
elements-9064	277	36	10421050	10421050	NUM
elements-9064	277	37	.	.	PUNCT
elements-9064	278	1	doi	doi	NOUN
elements-9064	278	2	:	:	PUNCT
elements-9064	278	3	10.1016	10.1016	NUM
elements-9064	278	4	/	/	SYM
elements-9064	278	5	j.str.2013.04.010	j.str.2013.04.010	PROPN
elements-9064	278	6	.	.	PUNCT
elements-9064	279	1	delport	delport	PROPN
elements-9064	279	2	,	,	PUNCT
elements-9064	279	3	w.	w.	PROPN
elements-9064	279	4	,	,	PUNCT
elements-9064	279	5	a.	a.	PROPN
elements-9064	279	6	f.	f.	PROPN
elements-9064	279	7	poon	poon	PROPN
elements-9064	279	8	,	,	PUNCT
elements-9064	279	9	s.	s.	PROPN
elements-9064	279	10	d.	d.	PROPN
elements-9064	279	11	frost	frost	PROPN
elements-9064	279	12	,	,	PUNCT
elements-9064	279	13	and	and	CCONJ
elements-9064	279	14	s.	s.	PROPN
elements-9064	279	15	l.	l.	PROPN
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elements-9064	279	17	pond	pond	PROPN
elements-9064	279	18	.	.	PUNCT
elements-9064	280	1	2010	2010	NUM
elements-9064	280	2	.	.	PUNCT
elements-9064	281	1	“	"	PUNCT
elements-9064	281	2	datamonkey	datamonkey	NOUN
elements-9064	281	3	2010	2010	NUM
elements-9064	281	4	:	:	PUNCT
elements-9064	281	5	a	a	DET
elements-9064	281	6	suite	suite	NOUN
elements-9064	281	7	of	of	ADP
elements-9064	281	8	phylogenetic	phylogenetic	ADJ
elements-9064	281	9	analysis	analysis	NOUN
elements-9064	281	10	tools	tool	NOUN
elements-9064	281	11	for	for	ADP
elements-9064	281	12	evolutionary	evolutionary	ADJ
elements-9064	281	13	biology	biology	NOUN
elements-9064	281	14	.	.	PUNCT
elements-9064	281	15	”	"	PUNCT
elements-9064	281	16	  	  	SPACE
elements-9064	281	17	bioinformatics	bioinformatic	NOUN
elements-9064	281	18	57	57	NUM
elements-9064	281	19	a	a	DET
elements-9064	281	20	biological	biological	ADJ
elements-9064	281	21	“	"	PUNCT
elements-9064	281	22	arms	arm	NOUN
elements-9064	281	23	race	race	NOUN
elements-9064	281	24	”	"	PUNCT
elements-9064	281	25	(	(	PUNCT
elements-9064	281	26	oxford	oxford	PROPN
elements-9064	281	27	,	,	PUNCT
elements-9064	281	28	england	england	PROPN
elements-9064	281	29	)	)	PUNCT
elements-9064	281	30	 	 	SPACE
elements-9064	281	31	26	26	NUM
elements-9064	281	32	(	(	PUNCT
elements-9064	281	33	19	19	NUM
elements-9064	281	34	):	):	PUNCT
elements-9064	281	35	2455	2455	NUM
elements-9064	281	36	-	-	SYM
elements-9064	281	37	2457	2457	NUM
elements-9064	281	38	.	.	PUNCT
elements-9064	282	1	doi	doi	NOUN
elements-9064	282	2	:	:	PUNCT
elements-9064	282	3	10.1093	10.1093	NUM
elements-9064	282	4	/	/	SYM
elements-9064	282	5	bioinformatics	bioinformatics	NOUN
elements-9064	282	6	/	/	SYM
elements-9064	282	7	btq429	btq429	PROPN
elements-9064	282	8	.	.	PUNCT
elements-9064	282	9	desimmie	desimmie	PROPN
elements-9064	282	10	,	,	PUNCT
elements-9064	282	11	b.	b.	PROPN
elements-9064	282	12	a.	a.	PROPN
elements-9064	282	13	,	,	PUNCT
elements-9064	282	14	k.	k.	PROPN
elements-9064	282	15	a.	a.	PROPN
elements-9064	282	16	delviks	delviks	PROPN
elements-9064	282	17	-	-	PUNCT
elements-9064	282	18	frankenberrry	frankenberrry	NOUN
elements-9064	282	19	,	,	PUNCT
elements-9064	282	20	r.	r.	PROPN
elements-9064	282	21	c.	c.	PROPN
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elements-9064	282	23	,	,	PUNCT
elements-9064	282	24	d.	d.	PROPN
elements-9064	282	25	qi	qi	PROPN
elements-9064	282	26	,	,	PUNCT
elements-9064	282	27	t.	t.	PROPN
elements-9064	282	28	izumi	izumi	PROPN
elements-9064	282	29	,	,	PUNCT
elements-9064	282	30	and	and	CCONJ
elements-9064	282	31	v.	v.	PROPN
elements-9064	282	32	k.	k.	PROPN
elements-9064	282	33	pathak	pathak	PROPN
elements-9064	282	34	.	.	PROPN
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elements-9064	283	2	.	.	PUNCT
elements-9064	284	1	“	"	PUNCT
elements-9064	284	2	multiple	multiple	ADJ
elements-9064	284	3	apobec3	apobec3	NOUN
elements-9064	284	4	restriction	restriction	NOUN
elements-9064	284	5	factors	factor	NOUN
elements-9064	284	6	for	for	ADP
elements-9064	284	7	hiv-1	hiv-1	X
elements-9064	284	8	and	and	CCONJ
elements-9064	284	9	one	one	NUM
elements-9064	284	10	vif	vif	NOUN
elements-9064	284	11	to	to	PART
elements-9064	284	12	rule	rule	VERB
elements-9064	284	13	them	they	PRON
elements-9064	284	14	all	all	PRON
elements-9064	284	15	.	.	PUNCT
elements-9064	284	16	”	"	PUNCT
elements-9064	284	17	 	 	SPACE
elements-9064	284	18	journal	journal	NOUN
elements-9064	284	19	of	of	ADP
elements-9064	284	20	molecular	molecular	ADJ
elements-9064	284	21	biology	biology	NOUN
elements-9064	284	22	 	 	SPACE
elements-9064	284	23	426	426	NUM
elements-9064	284	24	(	(	PUNCT
elements-9064	284	25	6	6	NUM
elements-9064	284	26	):	):	PUNCT
elements-9064	284	27	12201245	12201245	NUM
elements-9064	284	28	.	.	PUNCT
elements-9064	285	1	doi	doi	NOUN
elements-9064	285	2	:	:	PUNCT
elements-9064	285	3	10.1016	10.1016	NUM
elements-9064	285	4	/	/	SYM
elements-9064	285	5	j.jmb.2013.10.033	j.jmb.2013.10.033	PROPN
elements-9064	285	6	.	.	PROPN
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elements-9064	285	8	,	,	PUNCT
elements-9064	285	9	m.	m.	NOUN
elements-9064	285	10	and	and	CCONJ
elements-9064	285	11	h.	h.	PROPN
elements-9064	285	12	s.	s.	PROPN
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elements-9064	285	14	.	.	PUNCT
elements-9064	286	1	2010	2010	NUM
elements-9064	286	2	.	.	PUNCT
elements-9064	287	1	“	"	PUNCT
elements-9064	287	2	paleovirology	paleovirology	NOUN
elements-9064	287	3	--	--	PUNCT
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elements-9064	287	8	viruses	virus	NOUN
elements-9064	287	9	.	.	PUNCT
elements-9064	287	10	”	"	PUNCT
elements-9064	287	11	 	 	SPACE
elements-9064	287	12	plos	plos	PROPN
elements-9064	287	13	biology	biology	PROPN
elements-9064	287	14	 	 	SPACE
elements-9064	287	15	8	8	NUM
elements-9064	287	16	(	(	PUNCT
elements-9064	287	17	2	2	NUM
elements-9064	287	18	):	):	PUNCT
elements-9064	287	19	e1000301	e1000301	PROPN
elements-9064	287	20	.	.	PUNCT
elements-9064	287	21	doi	doi	NOUN
elements-9064	287	22	:	:	PUNCT
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elements-9064	287	24	/	/	SYM
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elements-9064	287	26	.	.	PUNCT
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elements-9064	288	5	,	,	PUNCT
elements-9064	288	6	k.	k.	PROPN
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elements-9064	288	8	,	,	PUNCT
elements-9064	288	9	e.	e.	PROPN
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elements-9064	288	11	,	,	PUNCT
elements-9064	288	12	e.	e.	PROPN
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elements-9064	288	14	,	,	PUNCT
elements-9064	288	15	t.	t.	PROPN
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elements-9064	288	17	,	,	PUNCT
elements-9064	288	18	w.	w.	PROPN
elements-9064	288	19	a.	a.	NOUN
elements-9064	288	20	haseltine	haseltine	PROPN
elements-9064	288	21	,	,	PUNCT
elements-9064	288	22	and	and	CCONJ
elements-9064	288	23	j.	j.	PROPN
elements-9064	288	24	sodroski	sodroski	PROPN
elements-9064	288	25	.	.	PROPN
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elements-9064	289	2	.	.	PUNCT
elements-9064	290	1	“	"	PUNCT
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elements-9064	290	10	virus	virus	NOUN
elements-9064	290	11	type	type	NOUN
elements-9064	290	12	1	1	NUM
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elements-9064	290	20	  	  	SPACE
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elements-9064	290	26	11	11	NUM
elements-9064	290	27	):	):	PUNCT
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elements-9064	290	29	-	-	SYM
elements-9064	290	30	6495	6495	NUM
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elements-9064	291	5	vif	vif	NOUN
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elements-9064	291	9	human	human	ADJ
elements-9064	291	10	immunodeficiency	immunodeficiency	NOUN
elements-9064	291	11	virus	virus	NOUN
elements-9064	291	12	type	type	NOUN
elements-9064	291	13	1	1	NUM
elements-9064	291	14	in	in	ADP
elements-9064	291	15	cd4	cd4	PROPN
elements-9064	291	16	+	+	PROPN
elements-9064	291	17	t	t	PROPN
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elements-9064	291	19	.	.	PUNCT
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elements-9064	292	2	,	,	PUNCT
elements-9064	292	3	r.	r.	PROPN
elements-9064	292	4	c.	c.	PROPN
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elements-9064	292	10	m.	m.	NOUN
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elements-9064	292	12	,	,	PUNCT
elements-9064	292	13	g.	g.	PROPN
elements-9064	292	14	m.	m.	PROPN
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elements-9064	292	16	,	,	PUNCT
elements-9064	292	17	m.	m.	PROPN
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elements-9064	292	19	,	,	PUNCT
elements-9064	292	20	b.	b.	PROPN
elements-9064	292	21	f.	f.	PROPN
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elements-9064	292	23	,	,	PUNCT
elements-9064	292	24	t.	t.	PROPN
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elements-9064	292	28	r.	r.	PROPN
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elements-9064	292	30	,	,	PUNCT
elements-9064	292	31	j.	j.	PROPN
elements-9064	292	32	oleske	oleske	PROPN
elements-9064	292	33	,	,	PUNCT
elements-9064	292	34	and	and	CCONJ
elements-9064	292	35	b.	b.	PROPN
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elements-9064	292	39	.	.	PUNCT
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elements-9064	293	4	and	and	CCONJ
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elements-9064	293	6	of	of	ADP
elements-9064	293	7	cytopathic	cytopathic	ADJ
elements-9064	293	8	retroviruses	retrovirus	NOUN
elements-9064	293	9	(	(	PUNCT
elements-9064	293	10	htlv	htlv	PROPN
elements-9064	293	11	-	-	PUNCT
elements-9064	293	12	iii	iii	PROPN
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elements-9064	293	16	with	with	ADP
elements-9064	293	17	aids	aid	NOUN
elements-9064	293	18	and	and	CCONJ
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elements-9064	293	20	risk	risk	NOUN
elements-9064	293	21	for	for	ADP
elements-9064	293	22	aids	aid	NOUN
elements-9064	293	23	.	.	PUNCT
elements-9064	293	24	”	"	PUNCT
elements-9064	293	25	 	 	SPACE
elements-9064	293	26	science	science	NOUN
elements-9064	293	27	(	(	PUNCT
elements-9064	293	28	new	new	PROPN
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elements-9064	293	30	,	,	PUNCT
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elements-9064	293	32	.	.	PROPN
elements-9064	293	33	)	)	PUNCT
elements-9064	293	34	 	 	SPACE
elements-9064	293	35	224	224	NUM
elements-9064	293	36	(	(	PUNCT
elements-9064	293	37	4648	4648	NUM
elements-9064	293	38	):	):	PUNCT
elements-9064	293	39	500	500	NUM
elements-9064	293	40	-	-	SYM
elements-9064	293	41	503	503	NUM
elements-9064	293	42	.	.	PUNCT
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elements-9064	294	2	,	,	PUNCT
elements-9064	294	3	r.	r.	PROPN
elements-9064	294	4	s.	s.	PROPN
elements-9064	294	5	,	,	PUNCT
elements-9064	294	6	j.	j.	PROPN
elements-9064	294	7	f.	f.	PROPN
elements-9064	294	8	hultquist	hultquist	PROPN
elements-9064	294	9	,	,	PUNCT
elements-9064	294	10	and	and	CCONJ
elements-9064	294	11	d.	d.	PROPN
elements-9064	294	12	t.	t.	PROPN
elements-9064	294	13	evans	evans	PROPN
elements-9064	294	14	.	.	PROPN
elements-9064	294	15	2012	2012	NUM
elements-9064	294	16	.	.	PUNCT
elements-9064	295	1	“	"	PUNCT
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elements-9064	295	3	restriction	restriction	NOUN
elements-9064	295	4	factors	factor	NOUN
elements-9064	295	5	of	of	ADP
elements-9064	295	6	human	human	ADJ
elements-9064	295	7	immunodeficiency	immunodeficiency	NOUN
elements-9064	295	8	virus	virus	NOUN
elements-9064	295	9	.	.	PUNCT
elements-9064	295	10	”	"	PUNCT
elements-9064	295	11	 	 	SPACE
elements-9064	295	12	the	the	DET
elements-9064	295	13	journal	journal	NOUN
elements-9064	295	14	of	of	ADP
elements-9064	295	15	biological	biological	ADJ
elements-9064	295	16	chemistry	chemistry	NOUN
elements-9064	295	17	 	 	SPACE
elements-9064	295	18	287	287	NUM
elements-9064	295	19	(	(	PUNCT
elements-9064	295	20	49	49	NUM
elements-9064	295	21	):	):	PUNCT
elements-9064	295	22	4087540883	4087540883	NUM
elements-9064	295	23	.	.	PUNCT
elements-9064	296	1	doi	doi	NOUN
elements-9064	296	2	:	:	PUNCT
elements-9064	296	3	10.1074	10.1074	NUM
elements-9064	296	4	/	/	SYM
elements-9064	296	5	jbc.r112.416925	jbc.r112.416925	PROPN
elements-9064	296	6	.	.	PROPN
elements-9064	296	7	hatziioannou	hatziioannou	NOUN
elements-9064	296	8	,	,	PUNCT
elements-9064	296	9	t.	t.	PROPN
elements-9064	296	10	and	and	CCONJ
elements-9064	296	11	d.	d.	PROPN
elements-9064	296	12	t.	t.	PROPN
elements-9064	296	13	evans	evans	PROPN
elements-9064	296	14	.	.	PROPN
elements-9064	296	15	2012	2012	NUM
elements-9064	296	16	.	.	PUNCT
elements-9064	297	1	“	"	PUNCT
elements-9064	297	2	animal	animal	NOUN
elements-9064	297	3	models	model	NOUN
elements-9064	297	4	for	for	ADP
elements-9064	297	5	hiv	hiv	PROPN
elements-9064	297	6	/	/	SYM
elements-9064	297	7	aids	aids	PROPN
elements-9064	297	8	research	research	NOUN
elements-9064	297	9	.	.	PUNCT
elements-9064	297	10	”	"	PUNCT
elements-9064	297	11	 	 	SPACE
elements-9064	297	12	nature	nature	NOUN
elements-9064	297	13	reviews.microbiology	reviews.microbiology	NOUN
elements-9064	297	14	  	  	SPACE
elements-9064	297	15	10	10	NUM
elements-9064	297	16	(	(	PUNCT
elements-9064	297	17	12	12	NUM
elements-9064	297	18	):	):	PUNCT
elements-9064	297	19	852	852	NUM
elements-9064	297	20	-	-	SYM
elements-9064	297	21	867	867	NUM
elements-9064	297	22	.	.	PUNCT
elements-9064	298	1	doi	doi	NOUN
elements-9064	298	2	:	:	PUNCT
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elements-9064	298	4	/	/	SYM
elements-9064	298	5	nrmicro2911	nrmicro2911	PROPN
elements-9064	298	6	.	.	PUNCT
elements-9064	299	1	he	he	PRON
elements-9064	299	2	,	,	PUNCT
elements-9064	299	3	z.	z.	PROPN
elements-9064	299	4	,	,	PUNCT
elements-9064	299	5	w.	w.	PROPN
elements-9064	299	6	zhang	zhang	PROPN
elements-9064	299	7	,	,	PUNCT
elements-9064	299	8	g.	g.	PROPN
elements-9064	299	9	chen	chen	PROPN
elements-9064	299	10	,	,	PUNCT
elements-9064	299	11	r.	r.	PROPN
elements-9064	299	12	xu	xu	PROPN
elements-9064	299	13	,	,	PUNCT
elements-9064	299	14	and	and	CCONJ
elements-9064	299	15	x.	x.	PROPN
elements-9064	299	16	f.	f.	PROPN
elements-9064	299	17	yu	yu	PROPN
elements-9064	299	18	.	.	PROPN
elements-9064	299	19	2008	2008	NUM
elements-9064	299	20	.	.	PUNCT
elements-9064	300	1	“	"	PUNCT
elements-9064	300	2	characterization	characterization	NOUN
elements-9064	300	3	of	of	ADP
elements-9064	300	4	conserved	conserved	ADJ
elements-9064	300	5	motifs	motif	NOUN
elements-9064	300	6	in	in	ADP
elements-9064	300	7	hiv-1	hiv-1	X
elements-9064	300	8	vif	vif	NOUN
elements-9064	300	9	required	require	VERB
elements-9064	300	10	for	for	ADP
elements-9064	300	11	apobec3	apobec3	ADP
elements-9064	300	12	g	g	PROPN
elements-9064	300	13	and	and	CCONJ
elements-9064	300	14	apobec3f	apobec3f	PROPN
elements-9064	300	15	interaction	interaction	NOUN
elements-9064	300	16	.	.	PUNCT
elements-9064	300	17	”	"	PUNCT
elements-9064	300	18	 	 	SPACE
elements-9064	300	19	journal	journal	NOUN
elements-9064	300	20	of	of	ADP
elements-9064	300	21	molecular	molecular	ADJ
elements-9064	300	22	biology	biology	NOUN
elements-9064	300	23	 	 	SPACE
elements-9064	300	24	381	381	NUM
elements-9064	300	25	(	(	PUNCT
elements-9064	300	26	4	4	NUM
elements-9064	300	27	):	):	PUNCT
elements-9064	300	28	1000	1000	NUM
elements-9064	300	29	-	-	SYM
elements-9064	300	30	1011	1011	NUM
elements-9064	300	31	.	.	PUNCT
elements-9064	301	1	doi	doi	NOUN
elements-9064	301	2	:	:	PUNCT
elements-9064	301	3	 	 	SPACE
elements-9064	301	4	10.1016	10.1016	NUM
elements-9064	301	5	/	/	SYM
elements-9064	301	6	j.	j.	PROPN
elements-9064	301	7	jmb.2008.06.061	jmb.2008.06.061	PROPN
elements-9064	301	8	.	.	PUNCT
elements-9064	302	1	hirsch	hirsch	PROPN
elements-9064	302	2	,	,	PUNCT
elements-9064	302	3	v.	v.	ADP
elements-9064	302	4	m.	m.	NOUN
elements-9064	302	5	,	,	PUNCT
elements-9064	302	6	r.	r.	PROPN
elements-9064	302	7	a.	a.	PROPN
elements-9064	302	8	olmsted	olmsted	PROPN
elements-9064	302	9	,	,	PUNCT
elements-9064	302	10	m.	m.	NOUN
elements-9064	302	11	murphey	murphey	PROPN
elements-9064	302	12	-	-	PUNCT
elements-9064	302	13	corb	corb	PROPN
elements-9064	302	14	,	,	PUNCT
elements-9064	302	15	r.	r.	PROPN
elements-9064	302	16	h.	h.	PROPN
elements-9064	302	17	purcell	purcell	PROPN
elements-9064	302	18	,	,	PUNCT
elements-9064	302	19	and	and	CCONJ
elements-9064	302	20	p.	p.	PROPN
elements-9064	302	21	r.	r.	PROPN
elements-9064	302	22	johnson	johnson	PROPN
elements-9064	302	23	.	.	PUNCT
elements-9064	302	24	1989	1989	NUM
elements-9064	302	25	.	.	PUNCT
elements-9064	303	1	“	"	PUNCT
elements-9064	303	2	an	an	DET
elements-9064	303	3	african	african	ADJ
elements-9064	303	4	primate	primate	NOUN
elements-9064	303	5	lentivirus	lentivirus	NOUN
elements-9064	303	6	(	(	PUNCT
elements-9064	303	7	sivsm	sivsm	NOUN
elements-9064	303	8	)	)	PUNCT
elements-9064	303	9	closely	closely	ADV
elements-9064	303	10	related	relate	VERB
elements-9064	303	11	to	to	ADP
elements-9064	303	12	hiv-2	hiv-2	NOUN
elements-9064	303	13	.	.	PUNCT
elements-9064	303	14	”	"	PUNCT
elements-9064	303	15	  	  	SPACE
elements-9064	303	16	nature	nature	NOUN
elements-9064	303	17	  	  	SPACE
elements-9064	303	18	339	339	NUM
elements-9064	303	19	(	(	PUNCT
elements-9064	303	20	6223	6223	NUM
elements-9064	303	21	):	):	PUNCT
elements-9064	303	22	389	389	NUM
elements-9064	303	23	-	-	SYM
elements-9064	303	24	392	392	NUM
elements-9064	303	25	.	.	PUNCT
elements-9064	304	1	holmes	holmes	PROPN
elements-9064	304	2	,	,	PUNCT
elements-9064	304	3	r.	r.	PROPN
elements-9064	304	4	k.	k.	PROPN
elements-9064	304	5	,	,	PUNCT
elements-9064	304	6	f.	f.	PROPN
elements-9064	304	7	a.	a.	PROPN
elements-9064	304	8	koning	koning	PROPN
elements-9064	304	9	,	,	PUNCT
elements-9064	304	10	k.	k.	PROPN
elements-9064	304	11	n.	n.	PROPN
elements-9064	304	12	bishop	bishop	PROPN
elements-9064	304	13	,	,	PUNCT
elements-9064	304	14	and	and	CCONJ
elements-9064	304	15	m.	m.	PROPN
elements-9064	304	16	h.	h.	PROPN
elements-9064	304	17	malim	malim	PROPN
elements-9064	304	18	.	.	PUNCT
elements-9064	304	19	2007	2007	NUM
elements-9064	304	20	.	.	PUNCT
elements-9064	305	1	“	"	PUNCT
elements-9064	305	2	apobec3f	apobec3f	PROPN
elements-9064	305	3	can	can	AUX
elements-9064	305	4	inhibit	inhibit	VERB
elements-9064	305	5	the	the	DET
elements-9064	305	6	accumulation	accumulation	NOUN
elements-9064	305	7	of	of	ADP
elements-9064	305	8	hiv-1	hiv-1	PUNCT
elements-9064	305	9	reverse	reverse	ADJ
elements-9064	305	10	transcription	transcription	NOUN
elements-9064	305	11	products	product	NOUN
elements-9064	305	12	in	in	ADP
elements-9064	305	13	the	the	DET
elements-9064	305	14	absence	absence	NOUN
elements-9064	305	15	of	of	ADP
elements-9064	305	16	hypermutation	hypermutation	NOUN
elements-9064	305	17	.	.	PUNCT
elements-9064	306	1	comparisons	comparison	NOUN
elements-9064	306	2	with	with	ADP
elements-9064	306	3	apobec3	apobec3	PROPN
elements-9064	306	4	g.	g.	PROPN
elements-9064	306	5	”	"	PUNCT
elements-9064	306	6	  	  	SPACE
elements-9064	306	7	the	the	DET
elements-9064	306	8	journal	journal	NOUN
elements-9064	306	9	of	of	ADP
elements-9064	306	10	biological	biological	ADJ
elements-9064	306	11	chemistry	chemistry	NOUN
elements-9064	306	12	 	 	SPACE
elements-9064	306	13	282	282	NUM
elements-9064	306	14	(	(	PUNCT
elements-9064	306	15	4	4	NUM
elements-9064	306	16	):	):	PUNCT
elements-9064	306	17	2587	2587	NUM
elements-9064	306	18	-	-	SYM
elements-9064	306	19	2595	2595	NUM
elements-9064	306	20	.	.	PUNCT
elements-9064	307	1	huet	huet	PROPN
elements-9064	307	2	,	,	PUNCT
elements-9064	307	3	t.	t.	PROPN
elements-9064	307	4	,	,	PUNCT
elements-9064	307	5	r.	r.	PROPN
elements-9064	307	6	cheynier	cheynier	PROPN
elements-9064	307	7	,	,	PUNCT
elements-9064	307	8	a.	a.	PROPN
elements-9064	307	9	meyerhans	meyerhans	PROPN
elements-9064	307	10	,	,	PUNCT
elements-9064	307	11	g.	g.	PROPN
elements-9064	307	12	roelants	roelant	NOUN
elements-9064	307	13	,	,	PUNCT
elements-9064	307	14	and	and	CCONJ
elements-9064	307	15	s.	s.	PROPN
elements-9064	307	16	wain	wain	PROPN
elements-9064	307	17	-	-	PUNCT
elements-9064	307	18	hobson	hobson	PROPN
elements-9064	307	19	.	.	PUNCT
elements-9064	307	20	1990	1990	NUM
elements-9064	307	21	.	.	PUNCT
elements-9064	308	1	“	"	PUNCT
elements-9064	308	2	genetic	genetic	ADJ
elements-9064	308	3	organization	organization	NOUN
elements-9064	308	4	of	of	ADP
elements-9064	308	5	a	a	DET
elements-9064	308	6	chimpanzee	chimpanzee	NOUN
elements-9064	308	7	lentivirus	lentivirus	NOUN
elements-9064	308	8	related	relate	VERB
elements-9064	308	9	to	to	ADP
elements-9064	308	10	hiv-1	hiv-1	NOUN
elements-9064	308	11	.	.	PUNCT
elements-9064	308	12	”	"	PUNCT
elements-9064	308	13	 	 	SPACE
elements-9064	308	14	nature	nature	NOUN
elements-9064	308	15	  	  	SPACE
elements-9064	308	16	345	345	NUM
elements-9064	308	17	(	(	PUNCT
elements-9064	308	18	6273	6273	NUM
elements-9064	308	19	):	):	PUNCT
elements-9064	308	20	356	356	NUM
elements-9064	308	21	-	-	SYM
elements-9064	308	22	359	359	NUM
elements-9064	308	23	.	.	PUNCT
elements-9064	309	1	hurst	hurst	PROPN
elements-9064	309	2	,	,	PUNCT
elements-9064	309	3	l.	l.	PROPN
elements-9064	309	4	d.	d.	PROPN
elements-9064	309	5	2002	2002	NUM
elements-9064	309	6	.	.	PUNCT
elements-9064	310	1	“	"	PUNCT
elements-9064	310	2	the	the	DET
elements-9064	310	3	ka	ka	PROPN
elements-9064	310	4	/	/	SYM
elements-9064	310	5	ks	ks	NOUN
elements-9064	310	6	ratio	ratio	NOUN
elements-9064	310	7	:	:	PUNCT
elements-9064	310	8	diagnosing	diagnose	VERB
elements-9064	310	9	the	the	DET
elements-9064	310	10	form	form	NOUN
elements-9064	310	11	of	of	ADP
elements-9064	310	12	sequence	sequence	NOUN
elements-9064	310	13	evolution	evolution	NOUN
elements-9064	310	14	.	.	PUNCT
elements-9064	310	15	”	"	PUNCT
elements-9064	310	16	 	 	SPACE
elements-9064	310	17	trends	trend	NOUN
elements-9064	310	18	in	in	ADP
elements-9064	310	19	genetics	genetics	NOUN
elements-9064	310	20	:	:	PUNCT
elements-9064	310	21	tig	tig	X
elements-9064	310	22	  	  	SPACE
elements-9064	310	23	18	18	NUM
elements-9064	310	24	(	(	PUNCT
elements-9064	310	25	9	9	NUM
elements-9064	310	26	):	):	PUNCT
elements-9064	310	27	486	486	NUM
elements-9064	310	28	.	.	PUNCT
elements-9064	310	29	huthoff	huthoff	PROPN
elements-9064	310	30	,	,	PUNCT
elements-9064	310	31	h.	h.	PROPN
elements-9064	310	32	and	and	CCONJ
elements-9064	310	33	m.	m.	PROPN
elements-9064	310	34	h.	h.	PROPN
elements-9064	310	35	malim	malim	PROPN
elements-9064	310	36	.	.	PUNCT
elements-9064	311	1	2007	2007	NUM
elements-9064	311	2	.	.	PUNCT
elements-9064	312	1	“	"	PUNCT
elements-9064	312	2	identification	identification	NOUN
elements-9064	312	3	of	of	ADP
elements-9064	312	4	amino	amino	NOUN
elements-9064	312	5	acid	acid	NOUN
elements-9064	312	6	residues	residue	NOUN
elements-9064	312	7	in	in	ADP
elements-9064	312	8	apobec3	apobec3	ADP
elements-9064	312	9	g	g	NOUN
elements-9064	312	10	required	require	VERB
elements-9064	312	11	for	for	ADP
elements-9064	312	12	regulation	regulation	NOUN
elements-9064	312	13	by	by	ADP
elements-9064	312	14	human	human	ADJ
elements-9064	312	15	immunodeficiency	immunodeficiency	NOUN
elements-9064	312	16	virus	virus	NOUN
elements-9064	312	17	type	type	NOUN
elements-9064	312	18	1	1	NUM
elements-9064	312	19	vif	vif	NOUN
elements-9064	312	20	and	and	CCONJ
elements-9064	312	21	virion	virion	NOUN
elements-9064	312	22	encapsidation	encapsidation	NOUN
elements-9064	312	23	.	.	PUNCT
elements-9064	312	24	”	"	PUNCT
elements-9064	312	25	  	  	SPACE
elements-9064	312	26	journal	journal	NOUN
elements-9064	312	27	of	of	ADP
elements-9064	312	28	virology	virology	NOUN
elements-9064	312	29	  	  	SPACE
elements-9064	312	30	81	81	NUM
elements-9064	312	31	(	(	PUNCT
elements-9064	312	32	8)	8)	NUM
elements-9064	312	33	:	:	SYM
elements-9064	312	34	38073815	38073815	NUM
elements-9064	312	35	.	.	PUNCT
elements-9064	313	1	doi	doi	NOUN
elements-9064	313	2	:	:	PUNCT
elements-9064	313	3	 	 	SPACE
elements-9064	313	4	10.1128	10.1128	NUM
elements-9064	313	5	/	/	SYM
elements-9064	313	6	jvi.02795	jvi.02795	NUM
elements-9064	313	7	-	-	SYM
elements-9064	313	8	06	06	NUM
elements-9064	313	9	.	.	PUNCT
elements-9064	314	1	jarmuz	jarmuz	PROPN
elements-9064	314	2	,	,	PUNCT
elements-9064	314	3	a.	a.	NOUN
elements-9064	314	4	,	,	PUNCT
elements-9064	314	5	a.	a.	NOUN
elements-9064	314	6	chester	chester	PROPN
elements-9064	314	7	,	,	PUNCT
elements-9064	314	8	j.	j.	PROPN
elements-9064	314	9	bayliss	bayliss	PROPN
elements-9064	314	10	,	,	PUNCT
elements-9064	314	11	j.	j.	PROPN
elements-9064	314	12	gisbourne	gisbourne	PROPN
elements-9064	314	13	,	,	PUNCT
elements-9064	314	14	i.	i.	PROPN
elements-9064	314	15	dunham	dunham	PROPN
elements-9064	314	16	,	,	PUNCT
elements-9064	314	17	j.	j.	PROPN
elements-9064	314	18	scott	scott	PROPN
elements-9064	314	19	,	,	PUNCT
elements-9064	314	20	and	and	CCONJ
elements-9064	314	21	n.	n.	PROPN
elements-9064	314	22	navaratnam	navaratnam	PROPN
elements-9064	314	23	.	.	PUNCT
elements-9064	315	1	2002	2002	NUM
elements-9064	315	2	.	.	PUNCT
elements-9064	316	1	“	"	PUNCT
elements-9064	316	2	an	an	DET
elements-9064	316	3	anthropoidspecific	anthropoidspecific	ADJ
elements-9064	316	4	locus	locus	NOUN
elements-9064	316	5	of	of	ADP
elements-9064	316	6	orphan	orphan	NOUN
elements-9064	316	7	c	c	NOUN
elements-9064	316	8	to	to	ADP
elements-9064	316	9	u	u	PRON
elements-9064	316	10	rna	rna	NOUN
elements-9064	316	11	-	-	PUNCT
elements-9064	316	12	editing	edit	VERB
elements-9064	316	13	enzymes	enzyme	NOUN
elements-9064	316	14	on	on	ADP
elements-9064	316	15	chromosome	chromosome	NOUN
elements-9064	316	16	22	22	NUM
elements-9064	316	17	.	.	PUNCT
elements-9064	316	18	”	"	PUNCT
elements-9064	316	19	 	 	SPACE
elements-9064	316	20	genomics	genomic	NOUN
elements-9064	316	21	 	 	SPACE
elements-9064	316	22	79	79	NUM
elements-9064	316	23	(	(	PUNCT
elements-9064	316	24	3	3	NUM
elements-9064	316	25	):	):	PUNCT
elements-9064	316	26	285	285	NUM
elements-9064	316	27	-	-	SYM
elements-9064	316	28	296	296	NUM
elements-9064	316	29	.	.	PUNCT
elements-9064	317	1	doi	doi	NOUN
elements-9064	317	2	:	:	PUNCT
elements-9064	317	3	 	 	SPACE
elements-9064	317	4	10.1006/	10.1006/	NUM
elements-9064	317	5	geno.2002.6718	geno.2002.6718	PROPN
elements-9064	317	6	.	.	PUNCT
elements-9064	318	1	koning	koning	PROPN
elements-9064	318	2	,	,	PUNCT
elements-9064	318	3	f.	f.	PROPN
elements-9064	318	4	a.	a.	PROPN
elements-9064	318	5	,	,	PUNCT
elements-9064	318	6	e.	e.	PROPN
elements-9064	318	7	n.	n.	PROPN
elements-9064	318	8	newman	newman	PROPN
elements-9064	318	9	,	,	PUNCT
elements-9064	318	10	e.	e.	PROPN
elements-9064	318	11	y.	y.	PROPN
elements-9064	318	12	kim	kim	PROPN
elements-9064	318	13	,	,	PUNCT
elements-9064	318	14	k.	k.	PROPN
elements-9064	318	15	j.	j.	PROPN
elements-9064	318	16	kunstman	kunstman	PROPN
elements-9064	318	17	,	,	PUNCT
elements-9064	318	18	s.	s.	PROPN
elements-9064	318	19	m.	m.	PROPN
elements-9064	318	20	wolinsky	wolinsky	PROPN
elements-9064	318	21	,	,	PUNCT
elements-9064	318	22	and	and	CCONJ
elements-9064	318	23	m.	m.	PROPN
elements-9064	318	24	h.	h.	PROPN
elements-9064	318	25	malim	malim	PROPN
elements-9064	318	26	.	.	PUNCT
elements-9064	319	1	2009	2009	NUM
elements-9064	319	2	.	.	PUNCT
elements-9064	320	1	“	"	PUNCT
elements-9064	320	2	defining	define	VERB
elements-9064	320	3	apobec3	apobec3	NOUN
elements-9064	320	4	expression	expression	NOUN
elements-9064	320	5	patterns	pattern	NOUN
elements-9064	320	6	in	in	ADP
elements-9064	320	7	human	human	ADJ
elements-9064	320	8	tissues	tissue	NOUN
elements-9064	320	9	and	and	CCONJ
elements-9064	320	10	hematopoietic	hematopoietic	ADJ
elements-9064	320	11	cell	cell	NOUN
elements-9064	320	12	subsets	subset	NOUN
elements-9064	320	13	.	.	PUNCT
elements-9064	320	14	”	"	PUNCT
elements-9064	320	15	  	  	SPACE
elements-9064	320	16	journal	journal	NOUN
elements-9064	320	17	of	of	ADP
elements-9064	320	18	virology	virology	NOUN
elements-9064	320	19	 	 	SPACE
elements-9064	320	20	83	83	NUM
elements-9064	320	21	(	(	PUNCT
elements-9064	320	22	18	18	NUM
elements-9064	320	23	):	):	PUNCT
elements-9064	320	24	94749485	94749485	NUM
elements-9064	320	25	.	.	PUNCT
elements-9064	321	1	doi	doi	NOUN
elements-9064	321	2	:	:	PUNCT
elements-9064	321	3	 	 	SPACE
elements-9064	321	4	10.1128	10.1128	NUM
elements-9064	321	5	/	/	SYM
elements-9064	321	6	jvi.01089	jvi.01089	NOUN
elements-9064	321	7	-	-	SYM
elements-9064	321	8	09	09	NUM
elements-9064	321	9	.	.	PUNCT
elements-9064	321	10	kosakovsky	kosakovsky	PROPN
elements-9064	321	11	pond	pond	PROPN
elements-9064	321	12	,	,	PUNCT
elements-9064	321	13	s.	s.	PROPN
elements-9064	321	14	l.	l.	PROPN
elements-9064	321	15	and	and	CCONJ
elements-9064	321	16	s.	s.	PROPN
elements-9064	321	17	d.	d.	PROPN
elements-9064	321	18	frost	frost	PROPN
elements-9064	321	19	.	.	PUNCT
elements-9064	322	1	2005	2005	NUM
elements-9064	322	2	.	.	PUNCT
elements-9064	323	1	“	"	PUNCT
elements-9064	323	2	datamonkey	datamonkey	NOUN
elements-9064	323	3	:	:	PUNCT
elements-9064	323	4	rapid	rapid	ADJ
elements-9064	323	5	detection	detection	NOUN
elements-9064	323	6	of	of	ADP
elements-9064	323	7	selective	selective	ADJ
elements-9064	323	8	pressure	pressure	NOUN
elements-9064	323	9	on	on	ADP
elements-9064	323	10	individual	individual	ADJ
elements-9064	323	11	sites	site	NOUN
elements-9064	323	12	of	of	ADP
elements-9064	323	13	codon	codon	ADJ
elements-9064	323	14	alignments	alignment	NOUN
elements-9064	323	15	.	.	PUNCT
elements-9064	323	16	”	"	PUNCT
elements-9064	323	17	 	 	SPACE
elements-9064	323	18	bioinformatics	bioinformatic	NOUN
elements-9064	323	19	(	(	PUNCT
elements-9064	323	20	oxford	oxford	PROPN
elements-9064	323	21	,	,	PUNCT
elements-9064	323	22	england	england	PROPN
elements-9064	323	23	)	)	PUNCT
elements-9064	323	24	  	  	SPACE
elements-9064	323	25	21	21	NUM
elements-9064	323	26	(	(	PUNCT
elements-9064	323	27	10	10	NUM
elements-9064	323	28	):	):	PUNCT
elements-9064	323	29	2531	2531	NUM
elements-9064	323	30	-	-	SYM
elements-9064	323	31	2533	2533	NUM
elements-9064	323	32	.	.	PUNCT
elements-9064	324	1	doi	doi	NOUN
elements-9064	324	2	:	:	PUNCT
elements-9064	324	3	  	  	SPACE
elements-9064	324	4	10.1093	10.1093	NUM
elements-9064	324	5	/	/	SYM
elements-9064	324	6	bioinformatics/	bioinformatics/	PROPN
elements-9064	324	7	bti320	bti320	NOUN
elements-9064	324	8	.	.	PUNCT
elements-9064	324	9	  	  	SPACE
elements-9064	324	10	kosakovsky	kosakovsky	PROPN
elements-9064	324	11	pond	pond	NOUN
elements-9064	324	12	,	,	PUNCT
elements-9064	324	13	s.	s.	PROPN
elements-9064	324	14	l.	l.	PROPN
elements-9064	324	15	and	and	CCONJ
elements-9064	324	16	s.	s.	PROPN
elements-9064	324	17	d.	d.	PROPN
elements-9064	324	18	frost	frost	PROPN
elements-9064	324	19	.	.	PUNCT
elements-9064	325	1	2005	2005	NUM
elements-9064	325	2	.	.	PUNCT
elements-9064	326	1	“	"	PUNCT
elements-9064	326	2	not	not	PART
elements-9064	326	3	so	so	ADV
elements-9064	326	4	different	different	ADJ
elements-9064	326	5	after	after	ADV
elements-9064	326	6	all	all	ADV
elements-9064	326	7	:	:	PUNCT
elements-9064	326	8	a	a	DET
elements-9064	326	9	comparison	comparison	NOUN
elements-9064	326	10	of	of	ADP
elements-9064	326	11	methods	method	NOUN
elements-9064	326	12	for	for	ADP
elements-9064	326	13	detecting	detect	VERB
elements-9064	326	14	amino	amino	NOUN
elements-9064	326	15	acid	acid	NOUN
elements-9064	326	16	sites	site	NOUN
elements-9064	326	17	under	under	ADP
elements-9064	326	18	selection	selection	NOUN
elements-9064	326	19	.	.	PUNCT
elements-9064	326	20	”	"	PUNCT
elements-9064	326	21	 	 	SPACE
elements-9064	326	22	molecular	molecular	ADJ
elements-9064	326	23	biology	biology	NOUN
elements-9064	326	24	and	and	CCONJ
elements-9064	326	25	evolution	evolution	NOUN
elements-9064	326	26	 	 	SPACE
elements-9064	326	27	22	22	NUM
elements-9064	326	28	(	(	PUNCT
elements-9064	326	29	5	5	NUM
elements-9064	326	30	):	):	PUNCT
elements-9064	326	31	1208	1208	NUM
elements-9064	326	32	-	-	SYM
elements-9064	326	33	1222	1222	NUM
elements-9064	326	34	.	.	PUNCT
elements-9064	327	1	doi	doi	NOUN
elements-9064	327	2	:	:	PUNCT
elements-9064	327	3	 	 	SPACE
elements-9064	327	4	10.1093	10.1093	NUM
elements-9064	327	5	/	/	SYM
elements-9064	327	6	molbev	molbev	NOUN
elements-9064	327	7	/	/	SYM
elements-9064	327	8	msi105	msi105	PROPN
elements-9064	327	9	.	.	PUNCT
elements-9064	328	1	kosakovsky	kosakovsky	PROPN
elements-9064	328	2	pond	pond	PROPN
elements-9064	328	3	,	,	PUNCT
elements-9064	328	4	s.	s.	PROPN
elements-9064	328	5	l.	l.	PROPN
elements-9064	328	6	,	,	PUNCT
elements-9064	328	7	s.	s.	PROPN
elements-9064	328	8	d.	d.	PROPN
elements-9064	328	9	frost	frost	PROPN
elements-9064	328	10	,	,	PUNCT
elements-9064	328	11	and	and	CCONJ
elements-9064	328	12	s.	s.	PROPN
elements-9064	328	13	v.	v.	PROPN
elements-9064	328	14	muse	muse	PROPN
elements-9064	328	15	.	.	PUNCT
elements-9064	329	1	2005	2005	NUM
elements-9064	329	2	.	.	PUNCT
elements-9064	330	1	“	"	PUNCT
elements-9064	330	2	hyphy	hyphy	NOUN
elements-9064	330	3	:	:	PUNCT
elements-9064	330	4	hypothesis	hypothesis	NOUN
elements-9064	330	5	testing	testing	NOUN
elements-9064	330	6	using	use	VERB
elements-9064	330	7	phylogenies	phylogeny	NOUN
elements-9064	330	8	.	.	PUNCT
elements-9064	330	9	”	"	PUNCT
elements-9064	330	10	 	 	SPACE
elements-9064	330	11	bioinformatics	bioinformatic	NOUN
elements-9064	330	12	(	(	PUNCT
elements-9064	330	13	oxford	oxford	PROPN
elements-9064	330	14	,	,	PUNCT
elements-9064	330	15	england	england	PROPN
elements-9064	330	16	)	)	PUNCT
elements-9064	330	17	 	 	SPACE
elements-9064	330	18	21	21	NUM
elements-9064	330	19	(	(	PUNCT
elements-9064	330	20	5	5	NUM
elements-9064	330	21	):	):	PUNCT
elements-9064	330	22	676	676	NUM
elements-9064	330	23	-	-	SYM
elements-9064	330	24	679	679	NUM
elements-9064	330	25	.	.	PUNCT
elements-9064	331	1	doi	doi	NOUN
elements-9064	331	2	:	:	PUNCT
elements-9064	331	3	 	 	SPACE
elements-9064	331	4	10.1093	10.1093	NUM
elements-9064	331	5	/	/	SYM
elements-9064	331	6	bioinformatics	bioinformatics	NOUN
elements-9064	331	7	/	/	SYM
elements-9064	331	8	bti079	bti079	PROPN
elements-9064	331	9	.	.	PUNCT
elements-9064	332	1	krupp	krupp	PROPN
elements-9064	332	2	,	,	PUNCT
elements-9064	332	3	a.	a.	PROPN
elements-9064	332	4	,	,	PUNCT
elements-9064	332	5	k.	k.	PROPN
elements-9064	332	6	r.	r.	PROPN
elements-9064	332	7	mccarthy	mccarthy	PROPN
elements-9064	332	8	,	,	PUNCT
elements-9064	332	9	m.	m.	NOUN
elements-9064	332	10	ooms	oom	NOUN
elements-9064	332	11	,	,	PUNCT
elements-9064	332	12	m.	m.	NOUN
elements-9064	332	13	letko	letko	PROPN
elements-9064	332	14	,	,	PUNCT
elements-9064	332	15	j.	j.	PROPN
elements-9064	332	16	s.	s.	PROPN
elements-9064	332	17	morgan	morgan	PROPN
elements-9064	332	18	,	,	PUNCT
elements-9064	332	19	v.	v.	PROPN
elements-9064	332	20	simon	simon	PROPN
elements-9064	332	21	,	,	PUNCT
elements-9064	332	22	and	and	CCONJ
elements-9064	332	23	w.	w.	PROPN
elements-9064	332	24	e.	e.	PROPN
elements-9064	332	25	johnson	johnson	PROPN
elements-9064	332	26	.	.	PUNCT
elements-9064	333	1	2013	2013	NUM
elements-9064	333	2	.	.	PUNCT
elements-9064	334	1	“	"	PUNCT
elements-9064	334	2	apobec3	apobec3	ADP
elements-9064	334	3	g	g	NOUN
elements-9064	334	4	poly58	poly58	NOUN
elements-9064	334	5	elements	element	NOUN
elements-9064	334	6	:	:	PUNCT
elements-9064	334	7	:	:	PUNCT
elements-9064	334	8	fall	fall	VERB
elements-9064	334	9	2015	2015	NUM
elements-9064	334	10	morphism	morphism	NOUN
elements-9064	334	11	as	as	ADP
elements-9064	334	12	a	a	DET
elements-9064	334	13	selective	selective	ADJ
elements-9064	334	14	barrier	barrier	NOUN
elements-9064	334	15	to	to	ADP
elements-9064	334	16	cross	cross	ADJ
elements-9064	334	17	-	-	ADJ
elements-9064	334	18	species	species	ADJ
elements-9064	334	19	transmission	transmission	NOUN
elements-9064	334	20	and	and	CCONJ
elements-9064	334	21	emergence	emergence	NOUN
elements-9064	334	22	of	of	ADP
elements-9064	334	23	pathogenic	pathogenic	ADJ
elements-9064	334	24	siv	siv	PROPN
elements-9064	334	25	and	and	CCONJ
elements-9064	334	26	aids	aid	NOUN
elements-9064	334	27	in	in	ADP
elements-9064	334	28	a	a	DET
elements-9064	334	29	primate	primate	ADJ
elements-9064	334	30	host	host	NOUN
elements-9064	334	31	.	.	PUNCT
elements-9064	334	32	”	"	PUNCT
elements-9064	334	33	  	  	SPACE
elements-9064	334	34	plos	plos	PROPN
elements-9064	334	35	pathogens	pathogen	NOUN
elements-9064	334	36	  	  	SPACE
elements-9064	334	37	9	9	NUM
elements-9064	334	38	(	(	PUNCT
elements-9064	334	39	10	10	NUM
elements-9064	334	40	):	):	PUNCT
elements-9064	334	41	e1003641	e1003641	PROPN
elements-9064	334	42	.	.	PUNCT
elements-9064	334	43	doi:10.1371	doi:10.1371	PROPN
elements-9064	334	44	/	/	SYM
elements-9064	334	45	journal.ppat.1003641	journal.ppat.1003641	PROPN
elements-9064	334	46	.	.	PROPN
elements-9064	334	47	land	land	PROPN
elements-9064	334	48	,	,	PUNCT
elements-9064	334	49	a.	a.	NOUN
elements-9064	334	50	m.	m.	NOUN
elements-9064	334	51	,	,	PUNCT
elements-9064	334	52	n.	n.	PROPN
elements-9064	334	53	m.	m.	PROPN
elements-9064	334	54	shaban	shaban	PROPN
elements-9064	334	55	,	,	PUNCT
elements-9064	334	56	l.	l.	PROPN
elements-9064	334	57	evans	evans	PROPN
elements-9064	334	58	,	,	PUNCT
elements-9064	334	59	j.	j.	PROPN
elements-9064	334	60	f.	f.	PROPN
elements-9064	334	61	hultquist	hultquist	PROPN
elements-9064	334	62	,	,	PUNCT
elements-9064	334	63	j.	j.	PROPN
elements-9064	334	64	s.	s.	PROPN
elements-9064	334	65	albin	albin	PROPN
elements-9064	334	66	,	,	PUNCT
elements-9064	334	67	and	and	CCONJ
elements-9064	334	68	r.	r.	PROPN
elements-9064	334	69	s.	s.	PROPN
elements-9064	334	70	harris	harris	PROPN
elements-9064	334	71	.	.	PROPN
elements-9064	334	72	2014	2014	NUM
elements-9064	334	73	.	.	PUNCT
elements-9064	335	1	“	"	PUNCT
elements-9064	335	2	apobec3f	apobec3f	PROPN
elements-9064	335	3	determinants	determinant	NOUN
elements-9064	335	4	of	of	ADP
elements-9064	335	5	hiv-1	hiv-1	X
elements-9064	335	6	vif	vif	NOUN
elements-9064	335	7	sensitivity	sensitivity	NOUN
elements-9064	335	8	.	.	PUNCT
elements-9064	335	9	”	"	PUNCT
elements-9064	335	10	 	 	SPACE
elements-9064	335	11	journal	journal	NOUN
elements-9064	335	12	of	of	ADP
elements-9064	335	13	virology	virology	NOUN
elements-9064	335	14	 	 	SPACE
elements-9064	335	15	88	88	NUM
elements-9064	335	16	(	(	PUNCT
elements-9064	335	17	21	21	NUM
elements-9064	335	18	):	):	PUNCT
elements-9064	335	19	1292312927	1292312927	NUM
elements-9064	335	20	.	.	PUNCT
elements-9064	336	1	doi:10.1128	doi:10.1128	NOUN
elements-9064	336	2	/	/	SYM
elements-9064	336	3	jvi.02362	jvi.02362	VERB
elements-9064	336	4	-	-	PUNCT
elements-9064	336	5	14	14	NUM
elements-9064	336	6	.	.	PUNCT
elements-9064	337	1	lochelt	lochelt	ADJ
elements-9064	337	2	,	,	PUNCT
elements-9064	337	3	m.	m.	NOUN
elements-9064	337	4	,	,	PUNCT
elements-9064	337	5	f.	f.	PROPN
elements-9064	337	6	romen	romen	PROPN
elements-9064	337	7	,	,	PUNCT
elements-9064	337	8	p.	p.	PROPN
elements-9064	337	9	bastone	bastone	PROPN
elements-9064	337	10	,	,	PUNCT
elements-9064	337	11	h.	h.	PROPN
elements-9064	337	12	muckenfuss	muckenfuss	PROPN
elements-9064	337	13	,	,	PUNCT
elements-9064	337	14	n.	n.	PROPN
elements-9064	337	15	kirchner	kirchner	PROPN
elements-9064	337	16	,	,	PUNCT
elements-9064	337	17	y.	y.	PROPN
elements-9064	337	18	b.	b.	PROPN
elements-9064	338	1	kim	kim	PROPN
elements-9064	338	2	,	,	PUNCT
elements-9064	338	3	u.	u.	PROPN
elements-9064	338	4	truyen	truyen	PROPN
elements-9064	338	5	,	,	PUNCT
elements-9064	338	6	et	et	PROPN
elements-9064	338	7	al	al	PROPN
elements-9064	338	8	.	.	PROPN
elements-9064	338	9	2005	2005	NUM
elements-9064	338	10	.	.	PUNCT
elements-9064	339	1	“	"	PUNCT
elements-9064	339	2	the	the	DET
elements-9064	339	3	antiretroviral	antiretroviral	ADJ
elements-9064	339	4	activity	activity	NOUN
elements-9064	339	5	of	of	ADP
elements-9064	339	6	apobec3	apobec3	NOUN
elements-9064	339	7	is	be	AUX
elements-9064	339	8	inhibited	inhibit	VERB
elements-9064	339	9	by	by	ADP
elements-9064	339	10	the	the	DET
elements-9064	339	11	foamy	foamy	ADJ
elements-9064	339	12	virus	virus	NOUN
elements-9064	339	13	accessory	accessory	NOUN
elements-9064	339	14	bet	bet	NOUN
elements-9064	339	15	protein	protein	NOUN
elements-9064	339	16	.	.	PUNCT
elements-9064	339	17	”	"	PUNCT
elements-9064	339	18	 	 	SPACE
elements-9064	339	19	proceedings	proceeding	NOUN
elements-9064	339	20	of	of	ADP
elements-9064	339	21	the	the	DET
elements-9064	339	22	national	national	PROPN
elements-9064	339	23	academy	academy	PROPN
elements-9064	339	24	of	of	ADP
elements-9064	339	25	sciences	sciences	PROPN
elements-9064	339	26	of	of	ADP
elements-9064	339	27	the	the	DET
elements-9064	339	28	united	united	PROPN
elements-9064	339	29	states	states	PROPN
elements-9064	339	30	of	of	ADP
elements-9064	339	31	america	america	PROPN
elements-9064	339	32	 	 	SPACE
elements-9064	339	33	102	102	NUM
elements-9064	339	34	(	(	PUNCT
elements-9064	339	35	22	22	NUM
elements-9064	339	36	):	):	PUNCT
elements-9064	339	37	79827987	79827987	NUM
elements-9064	339	38	.	.	PUNCT
elements-9064	340	1	doi	doi	NOUN
elements-9064	340	2	:	:	PUNCT
elements-9064	340	3	 	 	SPACE
elements-9064	340	4	10.1073	10.1073	NUM
elements-9064	340	5	/	/	SYM
elements-9064	340	6	pnas.0501445102	pnas.0501445102	PROPN
elements-9064	340	7	.	.	NOUN
elements-9064	340	8	mangeat	mangeat	PROPN
elements-9064	340	9	,	,	PUNCT
elements-9064	340	10	b.	b.	PROPN
elements-9064	340	11	,	,	PUNCT
elements-9064	340	12	p.	p.	PROPN
elements-9064	340	13	turelli	turelli	PROPN
elements-9064	340	14	,	,	PUNCT
elements-9064	340	15	g.	g.	PROPN
elements-9064	340	16	caron	caron	PROPN
elements-9064	340	17	,	,	PUNCT
elements-9064	340	18	m.	m.	PROPN
elements-9064	340	19	friedli	friedli	PROPN
elements-9064	340	20	,	,	PUNCT
elements-9064	340	21	l.	l.	PROPN
elements-9064	340	22	perrin	perrin	PROPN
elements-9064	340	23	,	,	PUNCT
elements-9064	340	24	and	and	CCONJ
elements-9064	340	25	d.	d.	PROPN
elements-9064	340	26	trono	trono	PROPN
elements-9064	340	27	.	.	PROPN
elements-9064	340	28	2003	2003	NUM
elements-9064	340	29	.	.	PUNCT
elements-9064	341	1	“	"	PUNCT
elements-9064	341	2	broad	broad	ADJ
elements-9064	341	3	antiretroviral	antiretroviral	ADJ
elements-9064	341	4	defence	defence	NOUN
elements-9064	341	5	by	by	ADP
elements-9064	341	6	human	human	ADJ
elements-9064	341	7	apobec3	apobec3	PROPN
elements-9064	341	8	g	g	PROPN
elements-9064	341	9	through	through	ADP
elements-9064	341	10	lethal	lethal	ADJ
elements-9064	341	11	editing	editing	NOUN
elements-9064	341	12	of	of	ADP
elements-9064	341	13	nascent	nascent	ADJ
elements-9064	341	14	reverse	reverse	ADJ
elements-9064	341	15	transcripts	transcript	NOUN
elements-9064	341	16	.	.	PUNCT
elements-9064	341	17	”	"	PUNCT
elements-9064	341	18	  	  	SPACE
elements-9064	341	19	nature	nature	NOUN
elements-9064	341	20	  	  	SPACE
elements-9064	341	21	424	424	NUM
elements-9064	341	22	(	(	PUNCT
elements-9064	341	23	6944	6944	NUM
elements-9064	341	24	):	):	PUNCT
elements-9064	341	25	99	99	NUM
elements-9064	341	26	-	-	SYM
elements-9064	341	27	103	103	NUM
elements-9064	341	28	.	.	PUNCT
elements-9064	342	1	doi	doi	NOUN
elements-9064	342	2	:	:	PUNCT
elements-9064	342	3	  	  	SPACE
elements-9064	342	4	10.1038/	10.1038/	NUM
elements-9064	342	5	nature01709	nature01709	PROPN
elements-9064	342	6	.	.	PUNCT
elements-9064	343	1	mansfield	mansfield	PROPN
elements-9064	343	2	,	,	PUNCT
elements-9064	343	3	k.	k.	PROPN
elements-9064	343	4	g.	g.	PROPN
elements-9064	343	5	,	,	PUNCT
elements-9064	343	6	n.	n.	PROPN
elements-9064	343	7	w.	w.	PROPN
elements-9064	343	8	lerch	lerch	PROPN
elements-9064	343	9	,	,	PUNCT
elements-9064	343	10	m.	m.	PROPN
elements-9064	343	11	b.	b.	PROPN
elements-9064	343	12	gardner	gardner	PROPN
elements-9064	343	13	,	,	PUNCT
elements-9064	343	14	and	and	CCONJ
elements-9064	343	15	a.	a.	NOUN
elements-9064	343	16	a.	a.	NOUN
elements-9064	343	17	lackner	lackner	PROPN
elements-9064	343	18	.	.	PUNCT
elements-9064	344	1	1995	1995	NUM
elements-9064	344	2	.	.	PUNCT
elements-9064	345	1	“	"	PUNCT
elements-9064	345	2	origins	origin	NOUN
elements-9064	345	3	of	of	ADP
elements-9064	345	4	simian	simian	ADJ
elements-9064	345	5	immunodeficiency	immunodeficiency	NOUN
elements-9064	345	6	virus	virus	NOUN
elements-9064	345	7	infection	infection	NOUN
elements-9064	345	8	in	in	ADP
elements-9064	345	9	macaques	macaque	NOUN
elements-9064	345	10	at	at	ADP
elements-9064	345	11	the	the	DET
elements-9064	345	12	new	new	PROPN
elements-9064	345	13	england	england	PROPN
elements-9064	345	14	regional	regional	PROPN
elements-9064	345	15	primate	primate	PROPN
elements-9064	345	16	research	research	NOUN
elements-9064	345	17	center	center	NOUN
elements-9064	345	18	.	.	PUNCT
elements-9064	345	19	”	"	PUNCT
elements-9064	345	20	 	 	SPACE
elements-9064	345	21	journal	journal	NOUN
elements-9064	345	22	of	of	ADP
elements-9064	345	23	medical	medical	ADJ
elements-9064	345	24	primatology	primatology	NOUN
elements-9064	345	25	24	24	NUM
elements-9064	345	26	(	(	PUNCT
elements-9064	345	27	3	3	NUM
elements-9064	345	28	):	):	PUNCT
elements-9064	345	29	116	116	NUM
elements-9064	345	30	-	-	SYM
elements-9064	345	31	122	122	NUM
elements-9064	345	32	.	.	PUNCT
elements-9064	346	1	marin	marin	NOUN
elements-9064	346	2	,	,	PUNCT
elements-9064	346	3	m.	m.	NOUN
elements-9064	346	4	,	,	PUNCT
elements-9064	346	5	k.	k.	PROPN
elements-9064	346	6	m.	m.	PROPN
elements-9064	346	7	rose	rise	VERB
elements-9064	346	8	,	,	PUNCT
elements-9064	346	9	s.	s.	PROPN
elements-9064	346	10	l.	l.	PROPN
elements-9064	346	11	kozak	kozak	PROPN
elements-9064	346	12	,	,	PUNCT
elements-9064	346	13	and	and	CCONJ
elements-9064	346	14	d.	d.	PROPN
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elements-9064	346	16	.	.	PUNCT
elements-9064	347	1	2003	2003	NUM
elements-9064	347	2	.	.	PUNCT
elements-9064	348	1	“	"	PUNCT
elements-9064	348	2	hiv-1	hiv-1	X
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elements-9064	348	6	the	the	DET
elements-9064	348	7	editing	edit	VERB
elements-9064	348	8	enzyme	enzyme	NOUN
elements-9064	348	9	apobec3	apobec3	ADP
elements-9064	348	10	g	g	NOUN
elements-9064	348	11	and	and	CCONJ
elements-9064	348	12	induces	induce	VERB
elements-9064	348	13	its	its	PRON
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elements-9064	348	15	.	.	PUNCT
elements-9064	348	16	”	"	PUNCT
elements-9064	348	17	 	 	SPACE
elements-9064	348	18	nature	nature	NOUN
elements-9064	348	19	medicine	medicine	NOUN
elements-9064	348	20	 	 	SPACE
elements-9064	348	21	9	9	NUM
elements-9064	348	22	(	(	PUNCT
elements-9064	348	23	11	11	NUM
elements-9064	348	24	):	):	PUNCT
elements-9064	348	25	13981403	13981403	NUM
elements-9064	348	26	.	.	PUNCT
elements-9064	349	1	doi	doi	NOUN
elements-9064	349	2	:	:	PUNCT
elements-9064	349	3	 	 	SPACE
elements-9064	349	4	10.1038	10.1038	NUM
elements-9064	349	5	/	/	SYM
elements-9064	349	6	nm946	nm946	PROPN
elements-9064	349	7	.	.	PUNCT
elements-9064	350	1	marx	marx	PROPN
elements-9064	350	2	,	,	PUNCT
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elements-9064	350	4	a.	a.	PROPN
elements-9064	350	5	,	,	PUNCT
elements-9064	350	6	c.	c.	PROPN
elements-9064	350	7	apetrei	apetrei	ADV
elements-9064	350	8	,	,	PUNCT
elements-9064	350	9	and	and	CCONJ
elements-9064	350	10	e.	e.	PROPN
elements-9064	350	11	drucker	drucker	PROPN
elements-9064	350	12	.	.	PUNCT
elements-9064	350	13	2004	2004	NUM
elements-9064	350	14	.	.	PUNCT
elements-9064	351	1	“	"	PUNCT
elements-9064	351	2	aids	aid	NOUN
elements-9064	351	3	as	as	ADP
elements-9064	351	4	a	a	DET
elements-9064	351	5	zoonosis	zoonosis	NOUN
elements-9064	351	6	?	?	PUNCT
elements-9064	352	1	confusion	confusion	NOUN
elements-9064	352	2	over	over	ADP
elements-9064	352	3	the	the	DET
elements-9064	352	4	origin	origin	NOUN
elements-9064	352	5	of	of	ADP
elements-9064	352	6	the	the	DET
elements-9064	352	7	virus	virus	NOUN
elements-9064	352	8	and	and	CCONJ
elements-9064	352	9	the	the	DET
elements-9064	352	10	origin	origin	NOUN
elements-9064	352	11	of	of	ADP
elements-9064	352	12	the	the	DET
elements-9064	352	13	epidemics	epidemic	NOUN
elements-9064	352	14	.	.	PUNCT
elements-9064	352	15	”	"	PUNCT
elements-9064	352	16	 	 	SPACE
elements-9064	352	17	journal	journal	NOUN
elements-9064	352	18	of	of	ADP
elements-9064	352	19	medical	medical	ADJ
elements-9064	352	20	primatology	primatology	NOUN
elements-9064	352	21	33	33	NUM
elements-9064	352	22	(	(	PUNCT
elements-9064	352	23	5	5	NUM
elements-9064	352	24	-	-	SYM
elements-9064	352	25	6	6	NUM
elements-9064	352	26	):	):	PUNCT
elements-9064	352	27	220	220	NUM
elements-9064	352	28	-	-	SYM
elements-9064	352	29	226	226	NUM
elements-9064	352	30	.	.	PUNCT
elements-9064	353	1	doi	doi	NOUN
elements-9064	353	2	:	:	PUNCT
elements-9064	353	3	 	 	SPACE
elements-9064	353	4	10.1111	10.1111	NUM
elements-9064	353	5	/	/	SYM
elements-9064	353	6	j.1600	j.1600	NOUN
elements-9064	353	7	-	-	PUNCT
elements-9064	353	8	0684.2004.00078.x	0684.2004.00078.x	PROPN
elements-9064	353	9	.	.	PUNCT
elements-9064	354	1	mccarthy	mccarthy	PROPN
elements-9064	354	2	,	,	PUNCT
elements-9064	354	3	k.	k.	PROPN
elements-9064	354	4	r.	r.	PROPN
elements-9064	354	5	and	and	CCONJ
elements-9064	354	6	w.	w.	PROPN
elements-9064	354	7	e.	e.	PROPN
elements-9064	354	8	johnson	johnson	PROPN
elements-9064	354	9	.	.	PUNCT
elements-9064	355	1	2014	2014	NUM
elements-9064	355	2	.	.	PUNCT
elements-9064	356	1	“	"	PUNCT
elements-9064	356	2	plastic	plastic	ADJ
elements-9064	356	3	proteins	protein	NOUN
elements-9064	356	4	and	and	CCONJ
elements-9064	356	5	monkey	monkey	NOUN
elements-9064	356	6	blocks	block	NOUN
elements-9064	356	7	:	:	PUNCT
elements-9064	356	8	how	how	SCONJ
elements-9064	356	9	lentiviruses	lentiviruse	NOUN
elements-9064	356	10	evolved	evolve	VERB
elements-9064	356	11	to	to	PART
elements-9064	356	12	replicate	replicate	VERB
elements-9064	356	13	in	in	ADP
elements-9064	356	14	the	the	DET
elements-9064	356	15	presence	presence	NOUN
elements-9064	356	16	of	of	ADP
elements-9064	356	17	primate	primate	ADJ
elements-9064	356	18	restriction	restriction	NOUN
elements-9064	356	19	factors	factor	NOUN
elements-9064	356	20	.	.	PUNCT
elements-9064	356	21	”	"	PUNCT
elements-9064	357	1	plos	plos	PROPN
elements-9064	357	2	pathogens	pathogen	NOUN
elements-9064	357	3	10	10	NUM
elements-9064	357	4	(	(	PUNCT
elements-9064	357	5	4	4	NUM
elements-9064	357	6	):	):	PUNCT
elements-9064	357	7	e1004017	e1004017	NUM
elements-9064	357	8	.	.	PUNCT
elements-9064	357	9	doi:10.1371/	doi:10.1371/	NOUN
elements-9064	357	10	journal	journal	NOUN
elements-9064	357	11	.	.	PUNCT
elements-9064	358	1	ppat.1004017	ppat.1004017	PROPN
elements-9064	358	2	.	.	PUNCT
elements-9064	358	3	meiering	meiering	PROPN
elements-9064	358	4	,	,	PUNCT
elements-9064	358	5	c.	c.	PROPN
elements-9064	358	6	d.	d.	PROPN
elements-9064	358	7	and	and	CCONJ
elements-9064	358	8	m.	m.	PROPN
elements-9064	358	9	l.	l.	PROPN
elements-9064	358	10	linial	linial	PROPN
elements-9064	358	11	.	.	PUNCT
elements-9064	359	1	2001	2001	NUM
elements-9064	359	2	.	.	PUNCT
elements-9064	360	1	“	"	PUNCT
elements-9064	360	2	historical	historical	ADJ
elements-9064	360	3	perspective	perspective	NOUN
elements-9064	360	4	of	of	ADP
elements-9064	360	5	foamy	foamy	ADJ
elements-9064	360	6	virus	virus	NOUN
elements-9064	360	7	epidemiology	epidemiology	NOUN
elements-9064	360	8	and	and	CCONJ
elements-9064	360	9	infection	infection	NOUN
elements-9064	360	10	.	.	PUNCT
elements-9064	360	11	”	"	PUNCT
elements-9064	360	12	 	 	SPACE
elements-9064	360	13	clinical	clinical	ADJ
elements-9064	360	14	microbiology	microbiology	NOUN
elements-9064	360	15	reviews	review	NOUN
elements-9064	360	16	 	 	SPACE
elements-9064	360	17	14	14	NUM
elements-9064	360	18	(	(	PUNCT
elements-9064	360	19	1	1	NUM
elements-9064	360	20	):	):	PUNCT
elements-9064	360	21	165	165	NUM
elements-9064	360	22	-	-	SYM
elements-9064	360	23	176	176	NUM
elements-9064	360	24	.	.	PUNCT
elements-9064	361	1	meyerson	meyerson	PROPN
elements-9064	361	2	,	,	PUNCT
elements-9064	361	3	n.	n.	PROPN
elements-9064	361	4	r.	r.	PROPN
elements-9064	361	5	and	and	CCONJ
elements-9064	361	6	s.	s.	PROPN
elements-9064	361	7	l.	l.	PROPN
elements-9064	361	8	sawyer	sawyer	PROPN
elements-9064	361	9	.	.	PUNCT
elements-9064	362	1	2011	2011	NUM
elements-9064	362	2	.	.	PUNCT
elements-9064	363	1	“	"	PUNCT
elements-9064	363	2	two	two	NUM
elements-9064	363	3	-	-	PUNCT
elements-9064	363	4	stepping	step	VERB
elements-9064	363	5	through	through	ADP
elements-9064	363	6	time	time	NOUN
elements-9064	363	7	:	:	PUNCT
elements-9064	363	8	mammals	mammal	NOUN
elements-9064	363	9	and	and	CCONJ
elements-9064	363	10	viruses	virus	NOUN
elements-9064	363	11	.	.	PUNCT
elements-9064	363	12	”	"	PUNCT
elements-9064	363	13	 	 	SPACE
elements-9064	363	14	trends	trend	NOUN
elements-9064	363	15	in	in	ADP
elements-9064	363	16	microbiology	microbiology	NOUN
elements-9064	363	17	 	 	SPACE
elements-9064	363	18	19	19	NUM
elements-9064	363	19	(	(	PUNCT
elements-9064	363	20	6	6	NUM
elements-9064	363	21	):	):	PUNCT
elements-9064	363	22	286	286	NUM
elements-9064	363	23	-	-	SYM
elements-9064	363	24	294	294	NUM
elements-9064	363	25	.	.	PUNCT
elements-9064	364	1	doi	doi	NOUN
elements-9064	364	2	:	:	PUNCT
elements-9064	364	3	 	 	SPACE
elements-9064	364	4	10.1016	10.1016	NUM
elements-9064	364	5	/	/	SYM
elements-9064	364	6	j.tim.2011.03.006	j.tim.2011.03.006	PROPN
elements-9064	364	7	.	.	PUNCT
elements-9064	365	1	murray	murray	PROPN
elements-9064	365	2	,	,	PUNCT
elements-9064	365	3	s.	s.	PROPN
elements-9064	365	4	m.	m.	PROPN
elements-9064	365	5	and	and	CCONJ
elements-9064	365	6	m.	m.	PROPN
elements-9064	365	7	l.	l.	PROPN
elements-9064	365	8	linial	linial	PROPN
elements-9064	365	9	.	.	PUNCT
elements-9064	366	1	2006	2006	NUM
elements-9064	366	2	.	.	PUNCT
elements-9064	367	1	“	"	PUNCT
elements-9064	367	2	foamy	foamy	ADJ
elements-9064	367	3	virus	virus	NOUN
elements-9064	367	4	infection	infection	NOUN
elements-9064	367	5	in	in	ADP
elements-9064	367	6	primates	primate	NOUN
elements-9064	367	7	.	.	PUNCT
elements-9064	367	8	”	"	PUNCT
elements-9064	367	9	 	 	SPACE
elements-9064	367	10	journal	journal	NOUN
elements-9064	367	11	of	of	ADP
elements-9064	367	12	medical	medical	ADJ
elements-9064	367	13	primatology	primatology	NOUN
elements-9064	367	14	 	 	SPACE
elements-9064	367	15	35	35	NUM
elements-9064	367	16	(	(	PUNCT
elements-9064	367	17	4	4	NUM
elements-9064	367	18	-	-	SYM
elements-9064	367	19	5	5	NUM
elements-9064	367	20	):	):	PUNCT
elements-9064	367	21	225	225	NUM
elements-9064	367	22	-	-	SYM
elements-9064	367	23	235	235	NUM
elements-9064	367	24	.	.	PUNCT
elements-9064	368	1	doi	doi	NOUN
elements-9064	368	2	:	:	PUNCT
elements-9064	368	3	 	 	SPACE
elements-9064	368	4	10.1111	10.1111	NUM
elements-9064	368	5	/	/	SYM
elements-9064	368	6	j.1600	j.1600	NOUN
elements-9064	368	7	-	-	PUNCT
elements-9064	368	8	0684.2006.00171.x	0684.2006.00171.x	NOUN
elements-9064	368	9	.	.	PUNCT
elements-9064	369	1	russell	russell	PROPN
elements-9064	369	2	,	,	PUNCT
elements-9064	369	3	r.	r.	PROPN
elements-9064	369	4	a.	a.	PROPN
elements-9064	369	5	and	and	CCONJ
elements-9064	369	6	v.	v.	PROPN
elements-9064	369	7	k.	k.	PROPN
elements-9064	369	8	pathak	pathak	PROPN
elements-9064	369	9	.	.	PROPN
elements-9064	369	10	2007	2007	NUM
elements-9064	369	11	.	.	PUNCT
elements-9064	370	1	“	"	PUNCT
elements-9064	370	2	identification	identification	NOUN
elements-9064	370	3	of	of	ADP
elements-9064	370	4	two	two	NUM
elements-9064	370	5	distinct	distinct	ADJ
elements-9064	370	6	human	human	ADJ
elements-9064	370	7	immunodeficiency	immunodeficiency	NOUN
elements-9064	370	8	virus	virus	NOUN
elements-9064	370	9	type	type	NOUN
elements-9064	370	10	1	1	NUM
elements-9064	370	11	vif	vif	NOUN
elements-9064	370	12	determinants	determinant	NOUN
elements-9064	370	13	critical	critical	ADJ
elements-9064	370	14	for	for	ADP
elements-9064	370	15	interactions	interaction	NOUN
elements-9064	370	16	with	with	ADP
elements-9064	370	17	human	human	ADJ
elements-9064	370	18	apobec3	apobec3	PROPN
elements-9064	370	19	g	g	PROPN
elements-9064	370	20	and	and	CCONJ
elements-9064	370	21	apobec3f	apobec3f	PROPN
elements-9064	370	22	.	.	PUNCT
elements-9064	370	23	”	"	PUNCT
elements-9064	370	24	 	 	SPACE
elements-9064	370	25	journal	journal	NOUN
elements-9064	370	26	of	of	ADP
elements-9064	370	27	virology	virology	NOUN
elements-9064	370	28	 	 	SPACE
elements-9064	370	29	81	81	NUM
elements-9064	370	30	(	(	PUNCT
elements-9064	370	31	15	15	NUM
elements-9064	370	32	):	):	PUNCT
elements-9064	370	33	82018210	82018210	NUM
elements-9064	370	34	.	.	PUNCT
elements-9064	371	1	doi	doi	NOUN
elements-9064	371	2	:	:	PUNCT
elements-9064	371	3	 	 	SPACE
elements-9064	371	4	10.1128	10.1128	NUM
elements-9064	371	5	/	/	SYM
elements-9064	371	6	jvi.00395	jvi.00395	NOUN
elements-9064	371	7	-	-	PUNCT
elements-9064	371	8	07	07	NUM
elements-9064	371	9	.	.	PUNCT
elements-9064	372	1	russell	russell	PROPN
elements-9064	372	2	,	,	PUNCT
elements-9064	372	3	r.	r.	PROPN
elements-9064	372	4	a.	a.	PROPN
elements-9064	372	5	,	,	PUNCT
elements-9064	372	6	h.	h.	PROPN
elements-9064	372	7	l.	l.	PROPN
elements-9064	372	8	wiegand	wiegand	PROPN
elements-9064	372	9	,	,	PUNCT
elements-9064	372	10	m.	m.	PROPN
elements-9064	372	11	d.	d.	PROPN
elements-9064	372	12	moore	moore	PROPN
elements-9064	372	13	,	,	PUNCT
elements-9064	372	14	a.	a.	NOUN
elements-9064	372	15	schafer	schafer	PROPN
elements-9064	372	16	,	,	PUNCT
elements-9064	372	17	m.	m.	NOUN
elements-9064	372	18	o.	o.	PROPN
elements-9064	372	19	mcclure	mcclure	PROPN
elements-9064	372	20	,	,	PUNCT
elements-9064	372	21	and	and	CCONJ
elements-9064	372	22	b.	b.	PROPN
elements-9064	372	23	r.	r.	PROPN
elements-9064	372	24	cullen	cullen	PROPN
elements-9064	372	25	.	.	PUNCT
elements-9064	373	1	2005	2005	NUM
elements-9064	373	2	.	.	PUNCT
elements-9064	374	1	“	"	PUNCT
elements-9064	374	2	foamy	foamy	ADJ
elements-9064	374	3	virus	virus	NOUN
elements-9064	374	4	bet	bet	NOUN
elements-9064	374	5	proteins	protein	NOUN
elements-9064	374	6	function	function	NOUN
elements-9064	374	7	as	as	ADP
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elements-9064	374	9	inhibitors	inhibitor	NOUN
elements-9064	374	10	of	of	ADP
elements-9064	374	11	the	the	DET
elements-9064	374	12	apobec3	apobec3	NOUN
elements-9064	374	13	family	family	NOUN
elements-9064	374	14	of	of	ADP
elements-9064	374	15	innate	innate	ADJ
elements-9064	374	16	antiretroviral	antiretroviral	ADJ
elements-9064	374	17	defense	defense	NOUN
elements-9064	374	18	factors	factor	NOUN
elements-9064	374	19	.	.	PUNCT
elements-9064	374	20	”	"	PUNCT
elements-9064	374	21	 	 	SPACE
elements-9064	374	22	journal	journal	NOUN
elements-9064	374	23	of	of	ADP
elements-9064	374	24	virology	virology	NOUN
elements-9064	374	25	 	 	SPACE
elements-9064	374	26	79	79	NUM
elements-9064	374	27	(	(	PUNCT
elements-9064	374	28	14	14	NUM
elements-9064	374	29	):	):	PUNCT
elements-9064	374	30	8724	8724	NUM
elements-9064	374	31	-	-	SYM
elements-9064	374	32	8731	8731	NUM
elements-9064	374	33	.	.	PUNCT
elements-9064	375	1	doi	doi	NOUN
elements-9064	375	2	:	:	PUNCT
elements-9064	375	3	 	 	SPACE
elements-9064	375	4	10.1128	10.1128	NUM
elements-9064	375	5	/	/	SYM
elements-9064	375	6	jvi.79.14.87248731.2005	jvi.79.14.87248731.2005	PROPN
elements-9064	375	7	sawyer	sawyer	PROPN
elements-9064	375	8	,	,	PUNCT
elements-9064	375	9	s.	s.	PROPN
elements-9064	375	10	l.	l.	PROPN
elements-9064	375	11	,	,	PUNCT
elements-9064	375	12	m.	m.	NOUN
elements-9064	375	13	emerman	emerman	PROPN
elements-9064	375	14	,	,	PUNCT
elements-9064	375	15	and	and	CCONJ
elements-9064	375	16	h.	h.	PROPN
elements-9064	375	17	s.	s.	PROPN
elements-9064	375	18	malik	malik	PROPN
elements-9064	375	19	.	.	PUNCT
elements-9064	376	1	2004	2004	NUM
elements-9064	376	2	.	.	PUNCT
elements-9064	377	1	“	"	PUNCT
elements-9064	377	2	ancient	ancient	ADJ
elements-9064	377	3	adaptive	adaptive	ADJ
elements-9064	377	4	evolution	evolution	NOUN
elements-9064	377	5	of	of	ADP
elements-9064	377	6	the	the	DET
elements-9064	377	7	primate	primate	ADJ
elements-9064	377	8	antiviral	antiviral	ADJ
elements-9064	377	9	dnaediting	dnaedite	VERB
elements-9064	377	10	enzyme	enzyme	NOUN
elements-9064	377	11	apobec3	apobec3	ADP
elements-9064	377	12	g.	g.	NOUN
elements-9064	377	13	”	"	PUNCT
elements-9064	377	14	 	 	SPACE
elements-9064	377	15	plos	plos	PROPN
elements-9064	377	16	biology	biology	NOUN
elements-9064	377	17	 	 	SPACE
elements-9064	377	18	2	2	NUM
elements-9064	377	19	(	(	PUNCT
elements-9064	377	20	9	9	NUM
elements-9064	377	21	):	):	PUNCT
elements-9064	377	22	e275	e275	PROPN
elements-9064	377	23	.	.	PUNCT
elements-9064	377	24	doi	doi	PROPN
elements-9064	377	25	:	:	PUNCT
elements-9064	377	26	 	 	SPACE
elements-9064	377	27	10.1371	10.1371	NUM
elements-9064	377	28	/	/	SYM
elements-9064	377	29	journal.pbio.0020275	journal.pbio.0020275	PROPN
elements-9064	377	30	.	.	PUNCT
elements-9064	378	1	sharp	sharp	PROPN
elements-9064	378	2	,	,	PUNCT
elements-9064	378	3	p.	p.	NOUN
elements-9064	378	4	m.	m.	NOUN
elements-9064	378	5	and	and	CCONJ
elements-9064	378	6	b.	b.	PROPN
elements-9064	378	7	h.	h.	PROPN
elements-9064	378	8	hahn	hahn	PROPN
elements-9064	378	9	.	.	PUNCT
elements-9064	379	1	2011	2011	NUM
elements-9064	379	2	.	.	PUNCT
elements-9064	380	1	“	"	PUNCT
elements-9064	380	2	origins	origin	NOUN
elements-9064	380	3	of	of	ADP
elements-9064	380	4	hiv	hiv	PROPN
elements-9064	380	5	and	and	CCONJ
elements-9064	380	6	the	the	DET
elements-9064	380	7	aids	aids	PROPN
elements-9064	380	8	pandemic	pandemic	ADJ
elements-9064	380	9	.	.	PUNCT
elements-9064	380	10	”	"	PUNCT
elements-9064	380	11	 	 	SPACE
elements-9064	380	12	cold	cold	ADJ
elements-9064	380	13	spring	spring	NOUN
elements-9064	380	14	harbor	harbor	NOUN
elements-9064	380	15	perspectives	perspective	NOUN
elements-9064	380	16	in	in	ADP
elements-9064	380	17	medicine	medicine	NOUN
elements-9064	380	18	 	 	SPACE
elements-9064	380	19	1	1	NUM
elements-9064	380	20	(	(	PUNCT
elements-9064	380	21	1	1	NUM
elements-9064	380	22	):	):	PUNCT
elements-9064	380	23	a006841	a006841	PROPN
elements-9064	380	24	.	.	PUNCT
elements-9064	381	1	doi	doi	NOUN
elements-9064	381	2	:	:	PUNCT
elements-9064	381	3	 	 	SPACE
elements-9064	381	4	10.1101	10.1101	NUM
elements-9064	381	5	/	/	SYM
elements-9064	381	6	cshperspect.a006841	cshperspect.a006841	NOUN
elements-9064	381	7	.	.	PUNCT
elements-9064	382	1	sheehy	sheehy	PROPN
elements-9064	382	2	,	,	PUNCT
elements-9064	382	3	a.	a.	NOUN
elements-9064	382	4	m.	m.	NOUN
elements-9064	382	5	,	,	PUNCT
elements-9064	382	6	n.	n.	PROPN
elements-9064	382	7	c.	c.	PROPN
elements-9064	382	8	gaddis	gaddis	PROPN
elements-9064	382	9	,	,	PUNCT
elements-9064	382	10	j.	j.	PROPN
elements-9064	382	11	d.	d.	PROPN
elements-9064	382	12	choi	choi	PROPN
elements-9064	382	13	,	,	PUNCT
elements-9064	382	14	and	and	CCONJ
elements-9064	382	15	m.	m.	PROPN
elements-9064	382	16	h.	h.	PROPN
elements-9064	382	17	malim	malim	PROPN
elements-9064	382	18	.	.	PUNCT
elements-9064	383	1	2002	2002	NUM
elements-9064	383	2	.	.	PUNCT
elements-9064	384	1	“	"	PUNCT
elements-9064	384	2	isolation	isolation	NOUN
elements-9064	384	3	of	of	ADP
elements-9064	384	4	a	a	DET
elements-9064	384	5	human	human	ADJ
elements-9064	384	6	gene	gene	NOUN
elements-9064	384	7	that	that	PRON
elements-9064	384	8	inhibits	inhibit	VERB
elements-9064	384	9	hiv-1	hiv-1	ADJ
elements-9064	384	10	infection	infection	NOUN
elements-9064	384	11	and	and	CCONJ
elements-9064	384	12	is	be	AUX
elements-9064	384	13	suppressed	suppress	VERB
elements-9064	384	14	by	by	ADP
elements-9064	384	15	the	the	DET
elements-9064	384	16	viral	viral	ADJ
elements-9064	384	17	vif	vif	NOUN
elements-9064	384	18	protein	protein	NOUN
elements-9064	384	19	.	.	PUNCT
elements-9064	384	20	”	"	PUNCT
elements-9064	384	21	 	 	SPACE
elements-9064	384	22	nature	nature	NOUN
elements-9064	384	23	 	 	SPACE
elements-9064	384	24	418	418	NUM
elements-9064	384	25	(	(	PUNCT
elements-9064	384	26	6898	6898	NUM
elements-9064	384	27	):	):	PUNCT
elements-9064	384	28	646	646	NUM
elements-9064	384	29	-	-	SYM
elements-9064	384	30	650	650	NUM
elements-9064	384	31	.	.	PUNCT
elements-9064	385	1	doi	doi	NOUN
elements-9064	385	2	:	:	PUNCT
elements-9064	385	3	 	 	SPACE
elements-9064	385	4	10.1038	10.1038	NUM
elements-9064	385	5	/	/	SYM
elements-9064	385	6	nature00969	nature00969	PROPN
elements-9064	385	7	.	.	PUNCT
elements-9064	386	1	sheehy	sheehy	PROPN
elements-9064	386	2	,	,	PUNCT
elements-9064	386	3	a.	a.	NOUN
elements-9064	386	4	m.	m.	NOUN
elements-9064	386	5	,	,	PUNCT
elements-9064	386	6	n.	n.	PROPN
elements-9064	386	7	c.	c.	PROPN
elements-9064	386	8	gaddis	gaddis	PROPN
elements-9064	386	9	,	,	PUNCT
elements-9064	386	10	and	and	CCONJ
elements-9064	386	11	m.	m.	PROPN
elements-9064	386	12	h.	h.	PROPN
elements-9064	386	13	malim	malim	PROPN
elements-9064	386	14	.	.	PUNCT
elements-9064	387	1	2003	2003	NUM
elements-9064	387	2	.	.	PUNCT
elements-9064	388	1	“	"	PUNCT
elements-9064	388	2	the	the	DET
elements-9064	388	3	antiretroviral	antiretroviral	ADJ
elements-9064	388	4	enzyme	enzyme	NOUN
elements-9064	388	5	apobec3	apobec3	ADP
elements-9064	388	6	g	g	NOUN
elements-9064	388	7	is	be	AUX
elements-9064	388	8	degraded	degrade	VERB
elements-9064	388	9	by	by	ADP
elements-9064	388	10	the	the	DET
elements-9064	388	11	proteasome	proteasome	NOUN
elements-9064	388	12	in	in	ADP
elements-9064	388	13	response	response	NOUN
elements-9064	388	14	to	to	ADP
elements-9064	388	15	hiv-1	hiv-1	X
elements-9064	388	16	vif	vif	NOUN
elements-9064	388	17	.	.	PUNCT
elements-9064	388	18	”	"	PUNCT
elements-9064	388	19	 	 	SPACE
elements-9064	388	20	nature	nature	NOUN
elements-9064	388	21	medicine	medicine	NOUN
elements-9064	388	22	 	 	SPACE
elements-9064	388	23	9	9	NUM
elements-9064	388	24	(	(	PUNCT
elements-9064	388	25	11	11	NUM
elements-9064	388	26	):	):	PUNCT
elements-9064	388	27	1404	1404	NUM
elements-9064	388	28	-	-	SYM
elements-9064	388	29	1407	1407	NUM
elements-9064	388	30	.	.	PUNCT
elements-9064	389	1	doi	doi	NOUN
elements-9064	389	2	:	:	PUNCT
elements-9064	389	3	 	 	SPACE
elements-9064	389	4	10.1038	10.1038	NUM
elements-9064	389	5	/	/	SYM
elements-9064	389	6	nm945	nm945	NOUN
elements-9064	389	7	.	.	PUNCT
elements-9064	390	1	simon	simon	PROPN
elements-9064	390	2	,	,	PUNCT
elements-9064	390	3	j.	j.	PROPN
elements-9064	390	4	h.	h.	PROPN
elements-9064	390	5	,	,	PUNCT
elements-9064	390	6	d.	d.	PROPN
elements-9064	390	7	l.	l.	PROPN
elements-9064	390	8	miller	miller	PROPN
elements-9064	390	9	,	,	PUNCT
elements-9064	390	10	r.	r.	PROPN
elements-9064	390	11	a.	a.	NOUN
elements-9064	390	12	fouchier	fouchier	PROPN
elements-9064	390	13	,	,	PUNCT
elements-9064	390	14	m.	m.	NOUN
elements-9064	390	15	a.	a.	PROPN
elements-9064	390	16	soares	soares	PROPN
elements-9064	390	17	,	,	PUNCT
elements-9064	390	18	k.	k.	PROPN
elements-9064	390	19	w.	w.	PROPN
elements-9064	390	20	peden	peden	PROPN
elements-9064	390	21	,	,	PUNCT
elements-9064	390	22	and	and	CCONJ
elements-9064	390	23	m.	m.	PROPN
elements-9064	390	24	h.	h.	PROPN
elements-9064	390	25	malim	malim	PROPN
elements-9064	390	26	.	.	PUNCT
elements-9064	390	27	1998	1998	NUM
elements-9064	390	28	.	.	PUNCT
elements-9064	391	1	“	"	PUNCT
elements-9064	391	2	the	the	DET
elements-9064	391	3	regulation	regulation	NOUN
elements-9064	391	4	of	of	ADP
elements-9064	391	5	primate	primate	ADJ
elements-9064	391	6	immunodeficiency	immunodeficiency	NOUN
elements-9064	391	7	virus	virus	NOUN
elements-9064	391	8	infectivity	infectivity	NOUN
elements-9064	391	9	by	by	ADP
elements-9064	391	10	vif	vif	PROPN
elements-9064	391	11	is	be	AUX
elements-9064	391	12	cell	cell	NOUN
elements-9064	391	13	species	specie	NOUN
elements-9064	391	14	restricted	restrict	VERB
elements-9064	391	15	:	:	PUNCT
elements-9064	391	16	a	a	DET
elements-9064	391	17	role	role	NOUN
elements-9064	391	18	for	for	ADP
elements-9064	391	19	vif	vif	NOUN
elements-9064	391	20	in	in	ADP
elements-9064	391	21	determining	determine	VERB
elements-9064	391	22	virus	virus	NOUN
elements-9064	391	23	host	host	NOUN
elements-9064	391	24	range	range	NOUN
elements-9064	391	25	and	and	CCONJ
elements-9064	391	26	cross	cross	ADJ
elements-9064	391	27	-	-	ADJ
elements-9064	391	28	species	species	ADJ
elements-9064	391	29	transmission	transmission	NOUN
elements-9064	391	30	.	.	PUNCT
elements-9064	391	31	”	"	PUNCT
elements-9064	391	32	 	 	SPACE
elements-9064	391	33	the	the	DET
elements-9064	391	34	embo	embo	PROPN
elements-9064	391	35	journal	journal	PROPN
elements-9064	391	36	 	 	SPACE
elements-9064	391	37	17	17	NUM
elements-9064	391	38	(	(	PUNCT
elements-9064	391	39	5	5	NUM
elements-9064	391	40	):	):	PUNCT
elements-9064	391	41	1259	1259	NUM
elements-9064	391	42	-	-	SYM
elements-9064	391	43	1267	1267	NUM
elements-9064	391	44	.	.	PUNCT
elements-9064	392	1	smith	smith	PROPN
elements-9064	392	2	,	,	PUNCT
elements-9064	392	3	j.	j.	PROPN
elements-9064	392	4	l.	l.	PROPN
elements-9064	392	5	and	and	CCONJ
elements-9064	392	6	v.	v.	PROPN
elements-9064	392	7	k.	k.	PROPN
elements-9064	392	8	pathak	pathak	PROPN
elements-9064	392	9	.	.	PUNCT
elements-9064	392	10	2010	2010	NUM
elements-9064	392	11	.	.	PUNCT
elements-9064	393	1	“	"	PUNCT
elements-9064	393	2	identification	identification	NOUN
elements-9064	393	3	of	of	ADP
elements-9064	393	4	specific	specific	ADJ
elements-9064	393	5	determinants	determinant	NOUN
elements-9064	393	6	of	of	ADP
elements-9064	393	7	human	human	ADJ
elements-9064	393	8	apobec3f	apobec3f	PROPN
elements-9064	393	9	,	,	PUNCT
elements-9064	393	10	apobec3c	apobec3c	PROPN
elements-9064	393	11	,	,	PUNCT
elements-9064	393	12	59	59	NUM
elements-9064	393	13	a	a	DET
elements-9064	393	14	biological	biological	ADJ
elements-9064	393	15	“	"	PUNCT
elements-9064	393	16	arms	arm	NOUN
elements-9064	393	17	race	race	NOUN
elements-9064	393	18	”	"	PUNCT
elements-9064	393	19	figure	figure	NOUN
elements-9064	393	20	1	1	NUM
elements-9064	393	21	:	:	PUNCT
elements-9064	393	22	a3	a3	NOUN
elements-9064	393	23	proteins	protein	NOUN
elements-9064	393	24	interfere	interfere	VERB
elements-9064	393	25	with	with	ADP
elements-9064	393	26	lentiviral	lentiviral	ADJ
elements-9064	393	27	replication	replication	NOUN
elements-9064	393	28	in	in	ADP
elements-9064	393	29	the	the	DET
elements-9064	393	30	absence	absence	NOUN
elements-9064	393	31	of	of	ADP
elements-9064	393	32	vif	vif	PROPN
elements-9064	393	33	.	.	PUNCT
elements-9064	394	1	the	the	DET
elements-9064	394	2	top	top	ADJ
elements-9064	394	3	half	half	NOUN
elements-9064	394	4	of	of	ADP
elements-9064	394	5	the	the	DET
elements-9064	394	6	figure	figure	NOUN
elements-9064	394	7	exemplifies	exemplify	VERB
elements-9064	394	8	a	a	DET
elements-9064	394	9	cell	cell	NOUN
elements-9064	394	10	infected	infect	VERB
elements-9064	394	11	with	with	ADP
elements-9064	394	12	a	a	DET
elements-9064	394	13	virus	virus	NOUN
elements-9064	394	14	that	that	PRON
elements-9064	394	15	does	do	AUX
elements-9064	394	16	not	not	PART
elements-9064	394	17	encode	encode	VERB
elements-9064	394	18	vif	vif	PROPN
elements-9064	394	19	.	.	PROPN
elements-9064	394	20	host	host	NOUN
elements-9064	394	21	a3	a3	NOUN
elements-9064	394	22	proteins	protein	NOUN
elements-9064	394	23	(	(	PUNCT
elements-9064	394	24	triangles	triangle	NOUN
elements-9064	394	25	)	)	PUNCT
elements-9064	394	26	incorporate	incorporate	VERB
elements-9064	394	27	into	into	ADP
elements-9064	394	28	a	a	DET
elements-9064	394	29	budding	bud	VERB
elements-9064	394	30	virion	virion	NOUN
elements-9064	394	31	,	,	PUNCT
elements-9064	394	32	and	and	CCONJ
elements-9064	394	33	then	then	ADV
elements-9064	394	34	interfere	interfere	VERB
elements-9064	394	35	with	with	ADP
elements-9064	394	36	the	the	DET
elements-9064	394	37	process	process	NOUN
elements-9064	394	38	of	of	ADP
elements-9064	394	39	reverse	reverse	ADJ
elements-9064	394	40	transcription	transcription	NOUN
elements-9064	394	41	in	in	ADP
elements-9064	394	42	the	the	DET
elements-9064	394	43	target	target	NOUN
elements-9064	394	44	cell	cell	NOUN
elements-9064	394	45	to	to	PART
elements-9064	394	46	prevent	prevent	VERB
elements-9064	394	47	further	further	ADJ
elements-9064	394	48	viral	viral	ADJ
elements-9064	394	49	replication	replication	NOUN
elements-9064	394	50	.	.	PUNCT
elements-9064	395	1	the	the	DET
elements-9064	395	2	bottom	bottom	ADJ
elements-9064	395	3	half	half	NOUN
elements-9064	395	4	of	of	ADP
elements-9064	395	5	the	the	DET
elements-9064	395	6	figure	figure	NOUN
elements-9064	395	7	exemplifies	exemplify	VERB
elements-9064	395	8	a	a	DET
elements-9064	395	9	cell	cell	NOUN
elements-9064	395	10	infected	infect	VERB
elements-9064	395	11	with	with	ADP
elements-9064	395	12	a	a	DET
elements-9064	395	13	virus	virus	NOUN
elements-9064	395	14	that	that	PRON
elements-9064	395	15	encodes	encode	VERB
elements-9064	395	16	vif	vif	PROPN
elements-9064	395	17	.	.	PUNCT
elements-9064	396	1	vif	vif	PROPN
elements-9064	396	2	(	(	PUNCT
elements-9064	396	3	¾	¾	NOUN
elements-9064	396	4	circles	circle	NOUN
elements-9064	396	5	)	)	PUNCT
elements-9064	396	6	prevents	prevent	VERB
elements-9064	396	7	a3	a3	NOUN
elements-9064	396	8	proteins	protein	NOUN
elements-9064	396	9	from	from	ADP
elements-9064	396	10	incorporating	incorporate	VERB
elements-9064	396	11	into	into	ADP
elements-9064	396	12	the	the	DET
elements-9064	396	13	budding	bud	VERB
elements-9064	396	14	virion	virion	NOUN
elements-9064	396	15	by	by	ADP
elements-9064	396	16	targeting	target	VERB
elements-9064	396	17	them	they	PRON
elements-9064	396	18	for	for	ADP
elements-9064	396	19	proteosomal	proteosomal	ADJ
elements-9064	396	20	degradation	degradation	NOUN
elements-9064	396	21	,	,	PUNCT
elements-9064	396	22	allowing	allow	VERB
elements-9064	396	23	replication	replication	NOUN
elements-9064	396	24	to	to	PART
elements-9064	396	25	continue	continue	VERB
elements-9064	396	26	unhindered	unhindered	ADJ
elements-9064	396	27	in	in	ADP
elements-9064	396	28	the	the	DET
elements-9064	396	29	target	target	NOUN
elements-9064	396	30	cell	cell	NOUN
elements-9064	396	31	.	.	PUNCT
elements-9064	397	1	and	and	CCONJ
elements-9064	397	2	apobec3de	apobec3de	PROPN
elements-9064	397	3	and	and	CCONJ
elements-9064	397	4	african	african	ADJ
elements-9064	397	5	green	green	ADJ
elements-9064	397	6	monkey	monkey	PROPN
elements-9064	397	7	apobec3f	apobec3f	PROPN
elements-9064	397	8	that	that	PRON
elements-9064	397	9	interact	interact	VERB
elements-9064	397	10	with	with	ADP
elements-9064	397	11	hiv-1	hiv-1	PUNCT
elements-9064	397	12	vif	vif	NOUN
elements-9064	397	13	.	.	PUNCT
elements-9064	397	14	”	"	PUNCT
elements-9064	397	15	 	 	SPACE
elements-9064	397	16	journal	journal	NOUN
elements-9064	397	17	of	of	ADP
elements-9064	397	18	virology	virology	NOUN
elements-9064	397	19	 	 	SPACE
elements-9064	397	20	84	84	NUM
elements-9064	397	21	(	(	PUNCT
elements-9064	397	22	24	24	NUM
elements-9064	397	23	):	):	PUNCT
elements-9064	397	24	12599	12599	NUM
elements-9064	397	25	-	-	SYM
elements-9064	397	26	12608	12608	NUM
elements-9064	397	27	.	.	PUNCT
elements-9064	398	1	doi	doi	NOUN
elements-9064	398	2	:	:	PUNCT
elements-9064	398	3	 	 	SPACE
elements-9064	398	4	10.1128	10.1128	NUM
elements-9064	398	5	/	/	SYM
elements-9064	398	6	jvi.01437	jvi.01437	NUM
elements-9064	398	7	-	-	PUNCT
elements-9064	398	8	10	10	NUM
elements-9064	398	9	.	.	PUNCT
elements-9064	399	1	sodroski	sodroski	PROPN
elements-9064	399	2	,	,	PUNCT
elements-9064	399	3	j.	j.	PROPN
elements-9064	399	4	,	,	PUNCT
elements-9064	399	5	w.	w.	PROPN
elements-9064	399	6	c.	c.	PROPN
elements-9064	399	7	goh	goh	PROPN
elements-9064	399	8	,	,	PUNCT
elements-9064	399	9	c.	c.	PROPN
elements-9064	399	10	rosen	rosen	PROPN
elements-9064	399	11	,	,	PUNCT
elements-9064	399	12	a.	a.	PROPN
elements-9064	399	13	tartar	tartar	PROPN
elements-9064	399	14	,	,	PUNCT
elements-9064	399	15	d.	d.	PROPN
elements-9064	399	16	portetelle	portetelle	PROPN
elements-9064	399	17	,	,	PUNCT
elements-9064	399	18	a.	a.	PROPN
elements-9064	399	19	burny	burny	PROPN
elements-9064	399	20	,	,	PUNCT
elements-9064	399	21	and	and	CCONJ
elements-9064	399	22	w.	w.	PROPN
elements-9064	399	23	haseltine	haseltine	PROPN
elements-9064	399	24	.	.	PUNCT
elements-9064	400	1	1986	1986	NUM
elements-9064	400	2	.	.	PUNCT
elements-9064	401	1	“	"	PUNCT
elements-9064	401	2	replicative	replicative	ADJ
elements-9064	401	3	and	and	CCONJ
elements-9064	401	4	cytopathic	cytopathic	ADJ
elements-9064	401	5	potential	potential	NOUN
elements-9064	401	6	of	of	ADP
elements-9064	401	7	htlv	htlv	PROPN
elements-9064	401	8	-	-	PUNCT
elements-9064	401	9	iii	iii	PROPN
elements-9064	401	10	/	/	SYM
elements-9064	401	11	lav	lav	NOUN
elements-9064	401	12	with	with	ADP
elements-9064	401	13	sor	sor	NOUN
elements-9064	401	14	gene	gene	NOUN
elements-9064	401	15	deletions	deletion	NOUN
elements-9064	401	16	.	.	PUNCT
elements-9064	401	17	”	"	PUNCT
elements-9064	401	18	 	 	SPACE
elements-9064	402	1	science	science	NOUN
elements-9064	402	2	(	(	PUNCT
elements-9064	402	3	new	new	PROPN
elements-9064	402	4	york	york	PROPN
elements-9064	402	5	,	,	PUNCT
elements-9064	402	6	n.y	n.y	PROPN
elements-9064	402	7	.	.	PROPN
elements-9064	402	8	)	)	PUNCT
elements-9064	402	9	 	 	SPACE
elements-9064	402	10	231	231	NUM
elements-9064	402	11	(	(	PUNCT
elements-9064	402	12	4745	4745	NUM
elements-9064	402	13	):	):	PUNCT
elements-9064	402	14	1549	1549	NUM
elements-9064	402	15	-	-	SYM
elements-9064	402	16	1553	1553	NUM
elements-9064	402	17	.	.	PUNCT
elements-9064	403	1	switzer	switzer	PROPN
elements-9064	403	2	,	,	PUNCT
elements-9064	403	3	w.	w.	PROPN
elements-9064	403	4	m.	m.	PROPN
elements-9064	403	5	,	,	PUNCT
elements-9064	403	6	m.	m.	NOUN
elements-9064	403	7	salemi	salemi	PROPN
elements-9064	403	8	,	,	PUNCT
elements-9064	403	9	v.	v.	ADP
elements-9064	403	10	shanmugam	shanmugam	PROPN
elements-9064	403	11	,	,	PUNCT
elements-9064	403	12	f.	f.	PROPN
elements-9064	403	13	gao	gao	PROPN
elements-9064	403	14	,	,	PUNCT
elements-9064	403	15	m.	m.	PROPN
elements-9064	403	16	e.	e.	PROPN
elements-9064	403	17	cong	cong	PROPN
elements-9064	403	18	,	,	PUNCT
elements-9064	403	19	c.	c.	PROPN
elements-9064	403	20	kuiken	kuiken	PROPN
elements-9064	403	21	,	,	PUNCT
elements-9064	403	22	v.	v.	ADP
elements-9064	403	23	bhullar	bhullar	NOUN
elements-9064	403	24	,	,	PUNCT
elements-9064	403	25	et	et	PROPN
elements-9064	403	26	al	al	PROPN
elements-9064	403	27	.	.	PROPN
elements-9064	403	28	2005	2005	NUM
elements-9064	403	29	.	.	PUNCT
elements-9064	404	1	“	"	PUNCT
elements-9064	404	2	ancient	ancient	ADJ
elements-9064	404	3	co	co	NOUN
elements-9064	404	4	-	-	NOUN
elements-9064	404	5	speciation	speciation	NOUN
elements-9064	404	6	of	of	ADP
elements-9064	404	7	simian	simian	ADJ
elements-9064	404	8	foamy	foamy	ADJ
elements-9064	404	9	viruses	virus	NOUN
elements-9064	404	10	and	and	CCONJ
elements-9064	404	11	primates	primate	NOUN
elements-9064	404	12	.	.	PUNCT
elements-9064	404	13	”	"	PUNCT
elements-9064	404	14	  	  	SPACE
elements-9064	404	15	nature	nature	NOUN
elements-9064	404	16	 	 	SPACE
elements-9064	404	17	434	434	NUM
elements-9064	404	18	(	(	PUNCT
elements-9064	404	19	7031	7031	NUM
elements-9064	404	20	):	):	PUNCT
elements-9064	404	21	376	376	NUM
elements-9064	404	22	-	-	SYM
elements-9064	404	23	380	380	NUM
elements-9064	404	24	.	.	PUNCT
elements-9064	405	1	doi	doi	NOUN
elements-9064	405	2	:	:	PUNCT
elements-9064	405	3	 	 	SPACE
elements-9064	405	4	10.1038	10.1038	NUM
elements-9064	405	5	/	/	SYM
elements-9064	405	6	nature03341	nature03341	PROPN
elements-9064	405	7	.	.	PROPN
elements-9064	406	1	vandewoude	vandewoude	PROPN
elements-9064	406	2	,	,	PUNCT
elements-9064	406	3	s.	s.	PROPN
elements-9064	406	4	and	and	CCONJ
elements-9064	406	5	c.	c.	PROPN
elements-9064	406	6	apetrei	apetrei	ADV
elements-9064	406	7	.	.	PUNCT
elements-9064	407	1	2006	2006	NUM
elements-9064	407	2	.	.	PUNCT
elements-9064	408	1	“	"	PUNCT
elements-9064	408	2	going	go	VERB
elements-9064	408	3	wild	wild	ADJ
elements-9064	408	4	:	:	PUNCT
elements-9064	408	5	lessons	lesson	NOUN
elements-9064	408	6	from	from	ADP
elements-9064	408	7	naturally	naturally	ADV
elements-9064	408	8	occurring	occur	VERB
elements-9064	408	9	t	t	PROPN
elements-9064	408	10	-	-	PUNCT
elements-9064	408	11	lymphotropic	lymphotropic	NOUN
elements-9064	408	12	lentiviruses	lentiviruse	NOUN
elements-9064	408	13	.	.	PUNCT
elements-9064	408	14	”	"	PUNCT
elements-9064	408	15	 	 	SPACE
elements-9064	408	16	clinical	clinical	ADJ
elements-9064	408	17	microbiology	microbiology	NOUN
elements-9064	408	18	reviews	review	NOUN
elements-9064	408	19	 	 	SPACE
elements-9064	408	20	19	19	NUM
elements-9064	408	21	(	(	PUNCT
elements-9064	408	22	4	4	NUM
elements-9064	408	23	):	):	PUNCT
elements-9064	408	24	728	728	NUM
elements-9064	408	25	-	-	SYM
elements-9064	408	26	762	762	NUM
elements-9064	408	27	.	.	PUNCT
elements-9064	408	28	wiegand	wiegand	NOUN
elements-9064	408	29	,	,	PUNCT
elements-9064	408	30	h.	h.	PROPN
elements-9064	408	31	l.	l.	PROPN
elements-9064	408	32	,	,	PUNCT
elements-9064	408	33	b.	b.	PROPN
elements-9064	409	1	p.	p.	PROPN
elements-9064	409	2	doehle	doehle	PROPN
elements-9064	409	3	,	,	PUNCT
elements-9064	409	4	h.	h.	PROPN
elements-9064	409	5	p.	p.	PROPN
elements-9064	409	6	bogerd	bogerd	PROPN
elements-9064	409	7	,	,	PUNCT
elements-9064	409	8	and	and	CCONJ
elements-9064	409	9	b.	b.	PROPN
elements-9064	409	10	r.	r.	PROPN
elements-9064	409	11	cullen	cullen	PROPN
elements-9064	409	12	.	.	PUNCT
elements-9064	410	1	2004	2004	NUM
elements-9064	410	2	.	.	PUNCT
elements-9064	411	1	“	"	PUNCT
elements-9064	411	2	a	a	DET
elements-9064	411	3	second	second	ADJ
elements-9064	411	4	human	human	ADJ
elements-9064	411	5	antiretroviral	antiretroviral	ADJ
elements-9064	411	6	factor	factor	NOUN
elements-9064	411	7	,	,	PUNCT
elements-9064	411	8	apobec3f	apobec3f	PROPN
elements-9064	411	9	,	,	PUNCT
elements-9064	411	10	is	be	AUX
elements-9064	411	11	suppressed	suppress	VERB
elements-9064	411	12	by	by	ADP
elements-9064	411	13	the	the	DET
elements-9064	411	14	hiv-1	hiv-1	ADJ
elements-9064	411	15	and	and	CCONJ
elements-9064	411	16	hiv-2	hiv-2	NUM
elements-9064	411	17	vif	vif	NOUN
elements-9064	411	18	proteins	protein	NOUN
elements-9064	411	19	.	.	PUNCT
elements-9064	411	20	”	"	PUNCT
elements-9064	411	21	 	 	SPACE
elements-9064	411	22	the	the	DET
elements-9064	411	23	embo	embo	PROPN
elements-9064	411	24	journal	journal	PROPN
elements-9064	411	25	 	 	SPACE
elements-9064	411	26	23	23	NUM
elements-9064	411	27	(	(	PUNCT
elements-9064	411	28	12	12	NUM
elements-9064	411	29	):	):	PUNCT
elements-9064	411	30	2451	2451	NUM
elements-9064	411	31	-	-	SYM
elements-9064	411	32	2458.60	2458.60	NUM
elements-9064	411	33	elements	element	NOUN
elements-9064	411	34	:	:	PUNCT
elements-9064	411	35	:	:	PUNCT
elements-9064	411	36	fall	fall	VERB
elements-9064	411	37	2015	2015	NUM
elements-9064	411	38	figure	figure	NOUN
elements-9064	411	39	2	2	NUM
elements-9064	411	40	:	:	PUNCT
elements-9064	411	41	distribution	distribution	NOUN
elements-9064	411	42	of	of	ADP
elements-9064	411	43	polymorphic	polymorphic	ADJ
elements-9064	411	44	sites	site	NOUN
elements-9064	411	45	in	in	ADP
elements-9064	411	46	rhesus	rhesus	NOUN
elements-9064	411	47	macaque	macaque	PROPN
elements-9064	411	48	a3f	a3f	PROPN
elements-9064	411	49	.	.	PUNCT
elements-9064	412	1	the	the	DET
elements-9064	412	2	dark	dark	ADJ
elements-9064	412	3	gray	gray	ADJ
elements-9064	412	4	boxes	box	NOUN
elements-9064	412	5	represent	represent	VERB
elements-9064	412	6	the	the	DET
elements-9064	412	7	cytidine	cytidine	NOUN
elements-9064	412	8	deaminase	deaminase	NOUN
elements-9064	412	9	domains	domain	NOUN
elements-9064	412	10	in	in	ADP
elements-9064	412	11	a3f	a3f	PROPN
elements-9064	412	12	,	,	PUNCT
elements-9064	412	13	and	and	CCONJ
elements-9064	412	14	the	the	DET
elements-9064	412	15	blue	blue	ADJ
elements-9064	412	16	shading	shading	NOUN
elements-9064	412	17	indicates	indicate	VERB
elements-9064	412	18	the	the	DET
elements-9064	412	19	catalytic	catalytic	ADJ
elements-9064	412	20	motif	motif	NOUN
elements-9064	412	21	.	.	PUNCT
elements-9064	413	1	the	the	DET
elements-9064	413	2	lines	line	NOUN
elements-9064	413	3	show	show	VERB
elements-9064	413	4	the	the	DET
elements-9064	413	5	approximate	approximate	ADJ
elements-9064	413	6	location	location	NOUN
elements-9064	413	7	of	of	ADP
elements-9064	413	8	sites	site	NOUN
elements-9064	413	9	found	find	VERB
elements-9064	413	10	to	to	PART
elements-9064	413	11	contain	contain	VERB
elements-9064	413	12	non	non	ADJ
elements-9064	413	13	-	-	ADJ
elements-9064	413	14	synonymous	synonymous	ADJ
elements-9064	413	15	polymorphisms	polymorphism	NOUN
elements-9064	413	16	in	in	ADP
elements-9064	413	17	two	two	NUM
elements-9064	413	18	or	or	CCONJ
elements-9064	413	19	more	more	ADJ
elements-9064	413	20	rhesus	rhesus	ADJ
elements-9064	413	21	macaque	macaque	ADJ
elements-9064	413	22	clones	clone	NOUN
elements-9064	413	23	.	.	PUNCT
elements-9064	414	1	the	the	DET
elements-9064	414	2	codon	codon	ADJ
elements-9064	414	3	numbers	number	NOUN
elements-9064	414	4	and	and	CCONJ
elements-9064	414	5	coded	code	VERB
elements-9064	414	6	amino	amino	ADJ
elements-9064	414	7	acids	acid	NOUN
elements-9064	414	8	are	be	AUX
elements-9064	414	9	indicated	indicate	VERB
elements-9064	414	10	above	above	ADP
elements-9064	414	11	or	or	CCONJ
elements-9064	414	12	below	below	ADP
elements-9064	414	13	the	the	DET
elements-9064	414	14	image	image	NOUN
elements-9064	414	15	.	.	PUNCT
elements-9064	415	1	only	only	ADV
elements-9064	415	2	polymorphisms	polymorphism	NOUN
elements-9064	415	3	that	that	PRON
elements-9064	415	4	were	be	AUX
elements-9064	415	5	seen	see	VERB
elements-9064	415	6	in	in	ADP
elements-9064	415	7	at	at	ADV
elements-9064	415	8	least	least	ADV
elements-9064	415	9	two	two	NUM
elements-9064	415	10	clones	clone	NOUN
elements-9064	415	11	are	be	AUX
elements-9064	415	12	included	include	VERB
elements-9064	415	13	.	.	PUNCT
elements-9064	416	1	bolded	bolde	VERB
elements-9064	416	2	lines	line	NOUN
elements-9064	416	3	and	and	CCONJ
elements-9064	416	4	codon	codon	NOUN
elements-9064	416	5	numbers	number	NOUN
elements-9064	416	6	indicate	indicate	VERB
elements-9064	416	7	that	that	SCONJ
elements-9064	416	8	the	the	DET
elements-9064	416	9	polymorphism	polymorphism	NOUN
elements-9064	416	10	was	be	AUX
elements-9064	416	11	found	find	VERB
elements-9064	416	12	in	in	ADP
elements-9064	416	13	multiple	multiple	ADJ
elements-9064	416	14	animals	animal	NOUN
elements-9064	416	15	.	.	PUNCT
elements-9064	417	1	figure	figure	VERB
elements-9064	417	2	3	3	NUM
elements-9064	417	3	:	:	PUNCT
elements-9064	417	4	inter	inter	ADJ
elements-9064	417	5	-	-	ADJ
elements-9064	417	6	species	species	ADJ
elements-9064	417	7	diversity	diversity	NOUN
elements-9064	417	8	of	of	ADP
elements-9064	417	9	a3f	a3f	PROPN
elements-9064	417	10	in	in	ADP
elements-9064	417	11	old	old	ADJ
elements-9064	417	12	world	world	NOUN
elements-9064	417	13	primates	primate	NOUN
elements-9064	417	14	.	.	PUNCT
elements-9064	418	1	the	the	DET
elements-9064	418	2	phylogenetic	phylogenetic	ADJ
elements-9064	418	3	tree	tree	NOUN
elements-9064	418	4	shows	show	VERB
elements-9064	418	5	the	the	DET
elements-9064	418	6	degree	degree	NOUN
elements-9064	418	7	of	of	ADP
elements-9064	418	8	divergence	divergence	NOUN
elements-9064	418	9	between	between	ADP
elements-9064	418	10	rhesus	rhesus	NOUN
elements-9064	418	11	macaque	macaque	ADJ
elements-9064	418	12	a3f	a3f	ADJ
elements-9064	418	13	clones	clone	NOUN
elements-9064	418	14	(	(	PUNCT
elements-9064	418	15	rh	rh	PROPN
elements-9064	418	16	)	)	PUNCT
elements-9064	418	17	,	,	PUNCT
elements-9064	418	18	sooty	sooty	NOUN
elements-9064	418	19	mangabey	mangabey	PROPN
elements-9064	418	20	a3f	a3f	PROPN
elements-9064	418	21	clones	clone	NOUN
elements-9064	418	22	(	(	PUNCT
elements-9064	418	23	sm	sm	NOUN
elements-9064	418	24	)	)	PUNCT
elements-9064	418	25	,	,	PUNCT
elements-9064	418	26	crab	crab	NOUN
elements-9064	418	27	-	-	PUNCT
elements-9064	418	28	eating	eat	VERB
elements-9064	418	29	macaque	macaque	ADJ
elements-9064	418	30	a3f	a3f	ADJ
elements-9064	418	31	clones	clone	NOUN
elements-9064	418	32	(	(	PUNCT
elements-9064	418	33	mf	mf	NOUN
elements-9064	418	34	)	)	PUNCT
elements-9064	418	35	,	,	PUNCT
elements-9064	418	36	and	and	CCONJ
elements-9064	418	37	pigtail	pigtail	ADJ
elements-9064	418	38	macaque	macaque	ADJ
elements-9064	418	39	a3f	a3f	ADJ
elements-9064	418	40	clones	clone	NOUN
elements-9064	418	41	(	(	PUNCT
elements-9064	418	42	mn	mn	PROPN
elements-9064	418	43	)	)	PUNCT
elements-9064	418	44	.	.	PUNCT
elements-9064	419	1	the	the	DET
elements-9064	419	2	species	specie	NOUN
elements-9064	419	3	tend	tend	VERB
elements-9064	419	4	to	to	PART
elements-9064	419	5	group	group	VERB
elements-9064	419	6	together	together	ADV
elements-9064	419	7	into	into	ADP
elements-9064	419	8	distinct	distinct	ADJ
elements-9064	419	9	lineages	lineage	NOUN
elements-9064	419	10	,	,	PUNCT
elements-9064	419	11	and	and	CCONJ
elements-9064	419	12	diversity	diversity	NOUN
elements-9064	419	13	within	within	ADP
elements-9064	419	14	species	specie	NOUN
elements-9064	419	15	is	be	AUX
elements-9064	419	16	evident	evident	ADJ
elements-9064	419	17	within	within	ADP
elements-9064	419	18	these	these	DET
elements-9064	419	19	lineages	lineage	NOUN
elements-9064	419	20	.	.	PUNCT
elements-9064	420	1	61	61	NUM
elements-9064	420	2	a	a	DET
elements-9064	420	3	biological	biological	ADJ
elements-9064	420	4	“	"	PUNCT
elements-9064	420	5	arms	arm	NOUN
elements-9064	420	6	race	race	NOUN
elements-9064	420	7	”	"	PUNCT
elements-9064	420	8	figure	figure	NOUN
elements-9064	420	9	4	4	NUM
elements-9064	420	10	:	:	PUNCT
elements-9064	420	11	distribution	distribution	NOUN
elements-9064	420	12	of	of	ADP
elements-9064	420	13	positively	positively	ADV
elements-9064	420	14	selected	select	VERB
elements-9064	420	15	sites	site	NOUN
elements-9064	420	16	in	in	ADP
elements-9064	420	17	primate	primate	NOUN
elements-9064	420	18	a3f	a3f	PROPN
elements-9064	420	19	.	.	PUNCT
elements-9064	421	1	the	the	DET
elements-9064	421	2	grey	grey	PROPN
elements-9064	421	3	boxes	box	NOUN
elements-9064	421	4	represent	represent	VERB
elements-9064	421	5	the	the	DET
elements-9064	421	6	cytidine	cytidine	NOUN
elements-9064	421	7	deaminase	deaminase	NOUN
elements-9064	421	8	domains	domain	NOUN
elements-9064	421	9	in	in	ADP
elements-9064	421	10	a3f	a3f	PROPN
elements-9064	421	11	,	,	PUNCT
elements-9064	421	12	and	and	CCONJ
elements-9064	421	13	the	the	DET
elements-9064	421	14	shaded	shade	VERB
elements-9064	421	15	areas	area	NOUN
elements-9064	421	16	indicates	indicate	VERB
elements-9064	421	17	the	the	DET
elements-9064	421	18	catalytic	catalytic	ADJ
elements-9064	421	19	motifs	motif	NOUN
elements-9064	421	20	.	.	PUNCT
elements-9064	422	1	the	the	DET
elements-9064	422	2	triangles	triangle	NOUN
elements-9064	422	3	show	show	VERB
elements-9064	422	4	the	the	DET
elements-9064	422	5	approximate	approximate	ADJ
elements-9064	422	6	locations	location	NOUN
elements-9064	422	7	of	of	ADP
elements-9064	422	8	positively	positively	ADV
elements-9064	422	9	selected	select	VERB
elements-9064	422	10	codons	codon	NOUN
elements-9064	422	11	identified	identify	VERB
elements-9064	422	12	via	via	ADP
elements-9064	422	13	dn	dn	PROPN
elements-9064	422	14	/	/	SYM
elements-9064	422	15	ds	ds	ADJ
elements-9064	422	16	analysis	analysis	NOUN
elements-9064	422	17	.	.	PUNCT
elements-9064	423	1	these	these	DET
elements-9064	423	2	sites	site	NOUN
elements-9064	423	3	are	be	AUX
elements-9064	423	4	distributed	distribute	VERB
elements-9064	423	5	fairly	fairly	ADV
elements-9064	423	6	evenly	evenly	ADV
elements-9064	423	7	throughout	throughout	ADP
elements-9064	423	8	the	the	DET
elements-9064	423	9	a3f	a3f	PROPN
elements-9064	423	10	gene	gene	NOUN
elements-9064	423	11	.	.	PUNCT
elements-9064	424	1	figure	figure	NOUN
elements-9064	424	2	5	5	NUM
elements-9064	424	3	:	:	PUNCT
elements-9064	424	4	a3f	a3f	ADJ
elements-9064	424	5	alleles	allele	NOUN
elements-9064	424	6	show	show	VERB
elements-9064	424	7	variable	variable	ADJ
elements-9064	424	8	levels	level	NOUN
elements-9064	424	9	of	of	ADP
elements-9064	424	10	expression	expression	NOUN
elements-9064	424	11	in	in	ADP
elements-9064	424	12	cell	cell	NOUN
elements-9064	424	13	culture	culture	NOUN
elements-9064	424	14	.	.	PUNCT
elements-9064	425	1	a3f	a3f	ADJ
elements-9064	425	2	expression	expression	NOUN
elements-9064	425	3	constructs	construct	NOUN
elements-9064	425	4	with	with	ADP
elements-9064	425	5	coding	code	VERB
elements-9064	425	6	sequence	sequence	NOUN
elements-9064	425	7	originating	originate	VERB
elements-9064	425	8	from	from	ADP
elements-9064	425	9	rhesus	rhesus	NOUN
elements-9064	425	10	macaques	macaque	NOUN
elements-9064	425	11	(	(	PUNCT
elements-9064	425	12	lanes	lane	NOUN
elements-9064	425	13	1	1	NUM
elements-9064	425	14	-	-	SYM
elements-9064	425	15	10	10	NUM
elements-9064	425	16	)	)	PUNCT
elements-9064	425	17	,	,	PUNCT
elements-9064	425	18	crab	crab	NOUN
elements-9064	425	19	-	-	PUNCT
elements-9064	425	20	eating	eat	VERB
elements-9064	425	21	macaques	macaque	NOUN
elements-9064	425	22	(	(	PUNCT
elements-9064	425	23	lanes	lane	NOUN
elements-9064	425	24	11	11	NUM
elements-9064	425	25	-	-	SYM
elements-9064	425	26	12	12	NUM
elements-9064	425	27	)	)	PUNCT
elements-9064	425	28	,	,	PUNCT
elements-9064	425	29	pigtail	pigtail	NOUN
elements-9064	425	30	macaques	macaque	NOUN
elements-9064	425	31	(	(	PUNCT
elements-9064	425	32	lanes	lane	VERB
elements-9064	425	33	13	13	NUM
elements-9064	425	34	-	-	SYM
elements-9064	425	35	14	14	NUM
elements-9064	425	36	)	)	PUNCT
elements-9064	425	37	,	,	PUNCT
elements-9064	425	38	or	or	CCONJ
elements-9064	425	39	sooty	sooty	NOUN
elements-9064	425	40	mangabeys	mangabey	NOUN
elements-9064	425	41	(	(	PUNCT
elements-9064	425	42	lanes	lane	NOUN
elements-9064	425	43	15	15	NUM
elements-9064	425	44	-	-	SYM
elements-9064	425	45	17	17	NUM
elements-9064	425	46	)	)	PUNCT
elements-9064	425	47	,	,	PUNCT
elements-9064	425	48	along	along	ADP
elements-9064	425	49	with	with	ADP
elements-9064	425	50	the	the	DET
elements-9064	425	51	rhesus	rhesus	NOUN
elements-9064	425	52	macaque	macaque	ADJ
elements-9064	425	53	patch	patch	NOUN
elements-9064	425	54	mutants	mutant	NOUN
elements-9064	425	55	(	(	PUNCT
elements-9064	425	56	lanes	lane	NOUN
elements-9064	425	57	18	18	NUM
elements-9064	425	58	-	-	SYM
elements-9064	425	59	20	20	NUM
elements-9064	425	60	)	)	PUNCT
elements-9064	425	61	were	be	AUX
elements-9064	425	62	transfected	transfecte	VERB
elements-9064	425	63	in	in	ADP
elements-9064	425	64	hek293	hek293	PROPN
elements-9064	425	65	t	t	NOUN
elements-9064	425	66	cells	cell	NOUN
elements-9064	425	67	.	.	PUNCT
elements-9064	426	1	cells	cell	NOUN
elements-9064	426	2	were	be	AUX
elements-9064	426	3	harvested	harvest	VERB
elements-9064	426	4	after	after	ADP
elements-9064	426	5	48	48	NUM
elements-9064	426	6	hours	hour	NOUN
elements-9064	426	7	,	,	PUNCT
elements-9064	426	8	and	and	CCONJ
elements-9064	426	9	proteins	protein	NOUN
elements-9064	426	10	were	be	AUX
elements-9064	426	11	separated	separate	VERB
elements-9064	426	12	via	via	ADP
elements-9064	426	13	sds	sds	PROPN
elements-9064	426	14	/	/	SYM
elements-9064	426	15	page	page	NOUN
elements-9064	426	16	and	and	CCONJ
elements-9064	426	17	visualized	visualize	VERB
elements-9064	426	18	via	via	ADP
elements-9064	426	19	western	western	ADJ
elements-9064	426	20	blot	blot	NOUN
elements-9064	426	21	(	(	PUNCT
elements-9064	426	22	see	see	VERB
elements-9064	426	23	immunoblotting	immunoblotting	NOUN
elements-9064	426	24	section	section	NOUN
elements-9064	426	25	in	in	ADP
elements-9064	426	26	materials	material	NOUN
elements-9064	426	27	and	and	CCONJ
elements-9064	426	28	methods	method	NOUN
elements-9064	426	29	)	)	PUNCT
elements-9064	426	30	.	.	PUNCT
elements-9064	427	1	62	62	NUM
elements-9064	427	2	elements	element	NOUN
elements-9064	427	3	:	:	PUNCT
elements-9064	427	4	:	:	PUNCT
elements-9064	427	5	fall	fall	VERB
elements-9064	427	6	2015	2015	NUM
elements-9064	427	7	figure	figure	NOUN
elements-9064	427	8	6	6	NUM
elements-9064	427	9	:	:	PUNCT
elements-9064	427	10	western	western	ADJ
elements-9064	427	11	blot	blot	NOUN
elements-9064	427	12	showing	show	VERB
elements-9064	427	13	rha3f	rha3f	VERB
elements-9064	427	14	susceptibility	susceptibility	NOUN
elements-9064	427	15	to	to	ADP
elements-9064	427	16	siv	siv	PROPN
elements-9064	427	17	vif	vif	PROPN
elements-9064	427	18	-	-	PUNCT
elements-9064	427	19	mediated	mediate	VERB
elements-9064	427	20	degradation	degradation	NOUN
elements-9064	427	21	.	.	PUNCT
elements-9064	428	1	a3	a3	NOUN
elements-9064	428	2	and	and	CCONJ
elements-9064	428	3	vif	vif	NOUN
elements-9064	428	4	expression	expression	NOUN
elements-9064	428	5	constructs	construct	NOUN
elements-9064	428	6	were	be	AUX
elements-9064	428	7	co	co	VERB
elements-9064	428	8	-	-	VERB
elements-9064	428	9	transfected	transfecte	VERB
elements-9064	428	10	into	into	ADP
elements-9064	428	11	hek293	hek293	PROPN
elements-9064	428	12	t	t	NOUN
elements-9064	428	13	cells	cell	NOUN
elements-9064	428	14	.	.	PUNCT
elements-9064	429	1	cells	cell	NOUN
elements-9064	429	2	were	be	AUX
elements-9064	429	3	harvested	harvest	VERB
elements-9064	429	4	48	48	NUM
elements-9064	429	5	hours	hour	NOUN
elements-9064	429	6	post	post	ADJ
elements-9064	429	7	-	-	NOUN
elements-9064	429	8	transfection	transfection	NOUN
elements-9064	429	9	and	and	CCONJ
elements-9064	429	10	proteins	protein	NOUN
elements-9064	429	11	were	be	AUX
elements-9064	429	12	separated	separate	VERB
elements-9064	429	13	via	via	ADP
elements-9064	429	14	sds	sds	PROPN
elements-9064	429	15	/	/	SYM
elements-9064	429	16	page	page	NOUN
elements-9064	429	17	and	and	CCONJ
elements-9064	429	18	visualized	visualize	VERB
elements-9064	429	19	via	via	ADP
elements-9064	429	20	western	western	ADJ
elements-9064	429	21	blot	blot	NOUN
elements-9064	429	22	(	(	PUNCT
elements-9064	429	23	see	see	VERB
elements-9064	429	24	immunoblotting	immunoblotting	NOUN
elements-9064	429	25	section	section	NOUN
elements-9064	429	26	in	in	ADP
elements-9064	429	27	materials	material	NOUN
elements-9064	429	28	and	and	CCONJ
elements-9064	429	29	methods	method	NOUN
elements-9064	429	30	)	)	PUNCT
elements-9064	429	31	.	.	PUNCT
elements-9064	430	1	the	the	DET
elements-9064	430	2	a3gs	a3gs	PROPN
elements-9064	430	3	were	be	AUX
elements-9064	430	4	included	include	VERB
elements-9064	430	5	as	as	ADP
elements-9064	430	6	controls	control	NOUN
elements-9064	430	7	for	for	ADP
elements-9064	430	8	vif	vif	NOUN
elements-9064	430	9	effectiveness	effectiveness	NOUN
elements-9064	430	10	,	,	PUNCT
elements-9064	430	11	as	as	SCONJ
elements-9064	430	12	their	their	PRON
elements-9064	430	13	susceptibilities	susceptibility	NOUN
elements-9064	430	14	to	to	ADP
elements-9064	430	15	these	these	DET
elements-9064	430	16	vifs	vif	NOUN
elements-9064	430	17	have	have	AUX
elements-9064	430	18	been	be	AUX
elements-9064	430	19	previously	previously	ADV
elements-9064	430	20	investigated	investigate	VERB
elements-9064	430	21	(	(	PUNCT
elements-9064	430	22	krupp	krupp	PROPN
elements-9064	430	23	et	et	PROPN
elements-9064	430	24	al	al	PROPN
elements-9064	430	25	.	.	PROPN
elements-9064	430	26	2013	2013	NUM
elements-9064	430	27	)	)	PUNCT
elements-9064	430	28	.	.	PUNCT
elements-9064	431	1	the	the	DET
elements-9064	431	2	rha3fs	rha3fs	NOUN
elements-9064	431	3	are	be	AUX
elements-9064	431	4	susceptible	susceptible	ADJ
elements-9064	431	5	to	to	ADP
elements-9064	431	6	sivsme041	sivsme041	PROPN
elements-9064	431	7	vif	vif	PROPN
elements-9064	431	8	and	and	CCONJ
elements-9064	431	9	sivstm	sivstm	PROPN
elements-9064	431	10	vif	vif	PROPN
elements-9064	431	11	,	,	PUNCT
elements-9064	431	12	but	but	CCONJ
elements-9064	431	13	are	be	AUX
elements-9064	431	14	resistant	resistant	ADJ
elements-9064	431	15	to	to	ADP
elements-9064	431	16	sivmac239	sivmac239	PROPN
elements-9064	431	17	vif	vif	PROPN
elements-9064	431	18	.	.	PUNCT
elements-9064	432	1	the	the	DET
elements-9064	432	2	fqqy	fqqy	ADJ
elements-9064	432	3	/	/	SYM
elements-9064	432	4	skeh	skeh	ADJ
elements-9064	432	5	patch	patch	NOUN
elements-9064	432	6	does	do	AUX
elements-9064	432	7	not	not	PART
elements-9064	432	8	affect	affect	VERB
elements-9064	432	9	susceptibility	susceptibility	NOUN
elements-9064	432	10	to	to	ADP
elements-9064	432	11	the	the	DET
elements-9064	432	12	vifs	vif	NOUN
elements-9064	432	13	tested	test	VERB
elements-9064	432	14	.	.	PUNCT
elements-9064	433	1	63	63	NUM
elements-9064	433	2	a	a	DET
elements-9064	433	3	biological	biological	ADJ
elements-9064	433	4	“	"	PUNCT
elements-9064	433	5	arms	arm	NOUN
elements-9064	433	6	race	race	NOUN
elements-9064	433	7	”	"	PUNCT