id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
ecj-10284	Turcato, Gianni; Zaboli, Arian; Tenci, Andrea; Ricci, Giorgio; Zannoni, Massimo; Scheurer, Christoph; Wieser, Anton; Maccagnani, Antonio; Bonora, Antonio; Pfeifer, Norbert	Safety and differences between direct oral anticoagulants and vitamin K antagonists in the risk of post-traumatic intrathoracic bleeding after rib fractures in elderly patients	2021	5	.pdf	application/pdf	4617	197	53	In addition, in cases of minor trauma (<3 rib fractures), no ITHs were observed in patients receiving DOACs.7 The elderly population is known to have a greater risk of trau- ma than younger individuals.1,3 Elderly patients’ falls frequently lead to visits to the ED and, though they generally have non-severe dynamics, they can lead to insidious traumatic conditions.1-3 In cases with the same severity and dynamics of the trauma, elderly patients have a risk of death twice as high as that of patients under 65 years of age.3 The risk of death over the age of 65 is esti- mated to increase by 6.8% each year due to the known fragility of the elderly, the high number of comorbidities and the chronic ther- apies commonly received by this population.2,3 Taking an OAT pre- trauma is a factor that promotes both immediate and delayed post- traumatic hemorrhage and can also cause serious hemorrhagic con- ditions even in non-severe trauma (minor head trauma, chest trau- ma, hip fracture).17,18 OAT can certainly cause problems in elderly and frail patients.19 Feeney et al. compared the risk of bleeding between patients taking VKAs and those taking DOACs in the case of severe closed trauma (ISS >15), excluding head trauma.22 In a cohort of 114 patients (78 VKAs vs 36 DOACs), patients receiving DOACs presented significantly lower mortality than those in the VKA group (DOACs group 8.3%, VKA group 29.5%, p=0.015), as well as a lower number of trans- fused units per patient (p=0.001).22 In contrast, as reported by Dennis et al., who focused on severe chest trauma with more than 3 rib fractures, the current study showed no difference between VKA and DOACs in this subgroup of more severe patients (14.3% vs 12.8%, p=807).7	cache/ecj-10284.pdf	txt/ecj-10284.txt