id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
ecj-10364	Rossi, Roberta; Castagno, Emanuele; Matarazzo, Patrizia; Tuli, Gerdi; Saracco, Paola; Urbino, Antonio F.; Bondone, Claudia	Severe hyponatremia due to water intoxication in a child with sickle cell disease: A case report	2022	3	.pdf	application/pdf	2645	148	50	Copeptin levels in water and sodium imbalance disorders associated to hyponatremia, such as Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) and cerebral/renal salt wasting, result higher than normal and urine osmolality is consequently also high.10-12 In our case, the time between water intake and seizures onset was approximately 12-24 hours, as already reported: the time sufficient to precipitate hyponatremic seizures after excessive water intake ranges from 90 minutes to 48 hours.1,4 Our patient also presented rhabdomyolysis, which is a known, but rare complication of hyponatremia, and whose underlying mechanism is still unclear. We report a case of acute hyponatremia due to water intoxication without Antidiuretic Hormone (ADH) excess in a child with sickle cell disease.	cache/ecj-10364.pdf	txt/ecj-10364.txt