id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
ecj-1079	Ferrari, R.; Giostra, F.; Agostinelli, D.; Monti, G.; Pomata, D. P.; Cavazza, M.	Noninvasive ventilation for acute exacerbations of chronic obstructive pulmonary disease in the emergency department: early predictors of in-hospital outcome	2012	1	.pdf	application/pdf	686	16	27	Università degli Studi di Bolo- gna, Alma Mater Studiorum Introduction The applications of early non-invasive ventilation (NIV) are nowadays expanding in the Emergency Department (ED) for the treatment of different types and etiologies of acute respiratory failure (ARF) Emergency physicians (EP) often face the challenge of predicting short-term outcomes for patients with ARF in the ED Aim To critically analyze and describe the impact of NIV and the peculiar characteristics connected to its use in the ED, with specific attention to ARF presentation due to acute exacerbation of chronic obstructive pulmonary disease (AECOPD) In our ED the global safety and efficacy of NIV in avoiding TI and improving the outcome of carefully selected and controlled patients admitted for ARF is confirmed and is similar to what has been documented in previous RCTs We showed the possibility to identify in the ED early predictors of outcome: some clinical parameters, biomarkers and arterial blood gas analysis data to recognize severe conditions and the response to treatment An appropriate patient selection and a properly timed intervention are required for the optimal administration of safe and effective early NIV in haemodynamically stable patients, not yet meeting criteria for IMV, who can be closely monitored in an environment where TI is promptly available, with a medical and nursing motivated team with an extensive training and experience in NIV Unnecessary delaying TI remains the major hazard of NIV in ARF.	cache/ecj-1079.pdf	txt/ecj-1079.txt