id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
ecj-11314	Vural, Nafis; Duyan, Murat; Saridas, Ali; Ertas, Elif; Kalkan, Asım	The predictive value of inflammatory biomarkers in the detection of multiple sclerosis attacks	2023	6	.pdf	application/pdf	4054	218	54	Introduction Multiple sclerosis (MS) is the most prevalent immune-media- ted inflammatory demyelinating central nervous system disorder, with a diverse set of clinical signs and symptoms.1,2 MS exhibits significant heterogeneity in radiological and histopathological changes, clinical presentation, disease progression, and treatment response.3 Regarding its pathogenesis, it has been suggested that the innate and adaptive immune system causes inflammation of a dynamic interaction between glia and neurons, disorders of the blood-brain barrier, demyelination, and neuroaxonal injury to the brain and spinal cord.4,5 Since MS patients admitted to the emergency department (ED) have variable clinical symptoms, it is very important to distinguish between those in the attack (exacerbation, relapse, episode) period and those who do not. In the study of Hemond et al. in MS patients, high MLR was significantly associated with physi- cal disability status score (EDSS) and brain atrophy.	cache/ecj-11314.pdf	txt/ecj-11314.txt