id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
ecj-12574	Minghetti, Sara; Lazzerotti, Alessandra; Sala, Debora; Vimercati , Chiara; Giudici, Sofia; Florio, Santa; Formica, Francesca; Zambrano, Stefania; Agarwal, Nivedita; Peruzzi, Cinzia	Neurotoxicity and PRES after severe citalopram intoxication in a 12-months-old baby	2024	5	.pdf	application/pdf	2948	171	46	Among SSRIs, citalopram has a high rate of seizures in over- dose and cardiac toxicity, most of all in doses higher than 400mg/day.4,5 Posterior Reversible Encephalopathy Syndrome (PRES) is described in adult patients with SSRI accidental inges- tions.6-9 When SS occurs in adults, cyproheptadine is used as an antidote (12-32 mg/day).10 Within this context, we review the liter- ature on pediatric citalopram intoxication and we describe the first case of pediatric SS with PRES after accidental ingestion of an unspecified dose of this drug treated with cyproheptadine. Antiseizures drugs such as valproic acid, lamotrigine, gabapentin, pregabalin, topiramate and carba- mazepine, phenytoin and oxcarbazepine could have serotoninergic properties and should be avoided in case of SS.18 In conclusion, pediatric citalopram intoxication could represent a severe neurological pediatric emergency with PRES features.	cache/ecj-12574.pdf	txt/ecj-12574.txt