id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
ecj-1630	Plebani, Mario; Zaninotto, Martina	Point: high-sensitive troponin assays – a valuable tool for astute physicians	2013	2	.pdf	application/pdf	2045	104	50	In fact, using sensitive assays, troponin con- centrations change very rapidly within shorter time intervals, thus allowing a more reliable rule-in process, and a reliable and more effi- cient rule-out strategy, which is even more important in emergency settings.14 Fourth, in real life high-sensitive troponins improve the diagnostic accuracy without sig- nificantly increasing the admission rates, as recently documented by Mion et al.15 Fifth, high-sensitive assays improve the risk stratification even in patients with normal concentrations of cardiac troponins measured with conventional assays.16 Sixth, high-sensitive assays improve the detection of minor myocardial damage in sev- eral clinical conditions, particularly in chemotherapy monitoring as well as in the administration of other drugs with side effects, thus allowing an early identification of myocardial damage.17 It has been demonstrat- ed that the early identification of myocardial damage using cardiac troponin assays may result in improved outcomes and reduction of the incidence of heart failure.18,19 In summary, a robust evidence has been col- lected to demonstrate the clinical effectiveness of high-sensitive assays for cardiac troponin. [Emergency Care Journal 2013; 9:e15] Point: high-sensitive troponin assays – a valuable tool for astute physicians Mario Plebani, Martina Zaninotto Department of Laboratory Medicine, University of Padua, Italy Dear Editor, A large body of evidence has been collected in the last decade to demonstrate the clinical value of cardiac troponins, both cardiac tro- ponin I (cTnI) and T (cTnI), as reference bio- chemical markers of myocardial injury.1,2	cache/ecj-1630.pdf	txt/ecj-1630.txt