id	sid	tid	token	lemma	pos
ecj-11500	1	1	hrev_master	hrev_master	NOUN
ecj-11500	2	1	[	[	X
ecj-11500	2	2	page	page	NOUN
ecj-11500	2	3	5	5	NUM
ecj-11500	2	4	]	]	PUNCT
ecj-11500	3	1	[	[	X
ecj-11500	3	2	emergency	emergency	NOUN
ecj-11500	3	3	care	care	NOUN
ecj-11500	3	4	journal	journal	NOUN
ecj-11500	3	5	2023	2023	NUM
ecj-11500	3	6	;	;	PUNCT
ecj-11500	3	7	19:11500	19:11500	NUM
ecj-11500	3	8	]	]	X
ecj-11500	3	9	emergency	emergency	NOUN
ecj-11500	3	10	care	care	NOUN
ecj-11500	3	11	journal	journal	PROPN
ecj-11500	3	12	2023	2023	NUM
ecj-11500	3	13	;	;	PUNCT
ecj-11500	3	14	volume	volume	NOUN
ecj-11500	3	15	19:15500	19:15500	NUM
ecj-11500	3	16	precision	precision	NOUN
ecj-11500	3	17	medicine	medicine	NOUN
ecj-11500	3	18	in	in	ADP
ecj-11500	3	19	hemostasis	hemostasis	NOUN
ecj-11500	3	20	:	:	PUNCT
ecj-11500	3	21	a	a	DET
ecj-11500	3	22	review	review	NOUN
ecj-11500	3	23	of	of	ADP
ecj-11500	3	24	prothrombin	prothrombin	ADJ
ecj-11500	3	25	complex	complex	ADJ
ecj-11500	3	26	concentrates	concentrate	NOUN
ecj-11500	3	27	and	and	CCONJ
ecj-11500	3	28	the	the	DET
ecj-11500	3	29	role	role	NOUN
ecj-11500	3	30	of	of	ADP
ecj-11500	3	31	viscoelastic	viscoelastic	ADJ
ecj-11500	3	32	tests	test	NOUN
ecj-11500	3	33	in	in	ADP
ecj-11500	3	34	tailoring	tailor	VERB
ecj-11500	3	35	therapy	therapy	NOUN
ecj-11500	3	36	iacopo	iacopo	PROPN
ecj-11500	3	37	cappellini	cappellini	PROPN
ecj-11500	3	38	,	,	PUNCT
ecj-11500	3	39	franco	franco	PROPN
ecj-11500	3	40	lai	lai	PROPN
ecj-11500	3	41	,	,	PUNCT
ecj-11500	3	42	simone	simone	NOUN
ecj-11500	3	43	magazzini	magazzini	PROPN
ecj-11500	3	44	,	,	PUNCT
ecj-11500	3	45	guglielmo	guglielmo	PROPN
ecj-11500	3	46	consales	consales	PROPN
ecj-11500	3	47	department	department	PROPN
ecj-11500	3	48	of	of	ADP
ecj-11500	3	49	emergency	emergency	NOUN
ecj-11500	3	50	and	and	CCONJ
ecj-11500	3	51	critical	critical	ADJ
ecj-11500	3	52	care	care	NOUN
ecj-11500	3	53	medicine	medicine	NOUN
ecj-11500	3	54	,	,	PUNCT
ecj-11500	3	55	azienda	azienda	PROPN
ecj-11500	3	56	usl	usl	PROPN
ecj-11500	3	57	toscana	toscana	PROPN
ecj-11500	3	58	centro	centro	PROPN
ecj-11500	3	59	,	,	PUNCT
ecj-11500	3	60	prato	prato	PROPN
ecj-11500	3	61	,	,	PUNCT
ecj-11500	3	62	italy	italy	PROPN
ecj-11500	3	63	abstract	abstract	ADJ
ecj-11500	3	64	this	this	DET
ecj-11500	3	65	review	review	NOUN
ecj-11500	3	66	explores	explore	VERB
ecj-11500	3	67	the	the	DET
ecj-11500	3	68	role	role	NOUN
ecj-11500	3	69	of	of	ADP
ecj-11500	3	70	precision	precision	NOUN
ecj-11500	3	71	medicine	medicine	NOUN
ecj-11500	3	72	in	in	ADP
ecj-11500	3	73	the	the	DET
ecj-11500	3	74	management	management	NOUN
ecj-11500	3	75	of	of	ADP
ecj-11500	3	76	bleeding	bleed	VERB
ecj-11500	3	77	disorders	disorder	NOUN
ecj-11500	3	78	and	and	CCONJ
ecj-11500	3	79	anticoagulation	anticoagulation	NOUN
ecj-11500	3	80	therapy	therapy	NOUN
ecj-11500	3	81	,	,	PUNCT
ecj-11500	3	82	with	with	ADP
ecj-11500	3	83	a	a	DET
ecj-11500	3	84	focus	focus	NOUN
ecj-11500	3	85	on	on	ADP
ecj-11500	3	86	the	the	DET
ecj-11500	3	87	use	use	NOUN
ecj-11500	3	88	of	of	ADP
ecj-11500	3	89	visco	visco	ADJ
ecj-11500	3	90	-	-	ADJ
ecj-11500	3	91	elastic	elastic	ADJ
ecj-11500	3	92	tests	test	NOUN
ecj-11500	3	93	such	such	ADJ
ecj-11500	3	94	as	as	ADP
ecj-11500	3	95	thromboelastography	thromboelastography	NOUN
ecj-11500	3	96	(	(	PUNCT
ecj-11500	3	97	teg	teg	NOUN
ecj-11500	3	98	)	)	PUNCT
ecj-11500	3	99	and	and	CCONJ
ecj-11500	3	100	rotational	rotational	ADJ
ecj-11500	3	101	thromboelastometry	thromboelastometry	NOUN
ecj-11500	3	102	(	(	PUNCT
ecj-11500	3	103	rotem	rotem	PROPN
ecj-11500	3	104	)	)	PUNCT
ecj-11500	3	105	.	.	PUNCT
ecj-11500	4	1	these	these	DET
ecj-11500	4	2	tests	test	NOUN
ecj-11500	4	3	provide	provide	VERB
ecj-11500	4	4	real	real	ADJ
ecj-11500	4	5	-	-	PUNCT
ecj-11500	4	6	time	time	NOUN
ecj-11500	4	7	,	,	PUNCT
ecj-11500	4	8	dynamic	dynamic	ADJ
ecj-11500	4	9	insight	insight	NOUN
ecj-11500	4	10	into	into	ADP
ecj-11500	4	11	a	a	DET
ecj-11500	4	12	patient	patient	NOUN
ecj-11500	4	13	’s	’s	PART
ecj-11500	4	14	coagulation	coagulation	NOUN
ecj-11500	4	15	status	status	NOUN
ecj-11500	4	16	,	,	PUNCT
ecj-11500	4	17	guiding	guide	VERB
ecj-11500	4	18	the	the	DET
ecj-11500	4	19	choice	choice	NOUN
ecj-11500	4	20	between	between	ADP
ecj-11500	4	21	three	three	NUM
ecj-11500	4	22	-	-	PUNCT
ecj-11500	4	23	factor	factor	NOUN
ecj-11500	4	24	prothrombin	prothrombin	NOUN
ecj-11500	4	25	complex	complex	ADJ
ecj-11500	4	26	concentrate	concentrate	NOUN
ecj-11500	4	27	(	(	PUNCT
ecj-11500	4	28	pcc3	pcc3	PROPN
ecj-11500	4	29	)	)	PUNCT
ecj-11500	4	30	and	and	CCONJ
ecj-11500	4	31	four	four	NUM
ecj-11500	4	32	-	-	PUNCT
ecj-11500	4	33	factor	factor	NOUN
ecj-11500	4	34	pcc	pcc	NOUN
ecj-11500	4	35	(	(	PUNCT
ecj-11500	4	36	pcc4	pcc4	PROPN
ecj-11500	4	37	)	)	PUNCT
ecj-11500	4	38	,	,	PUNCT
ecj-11500	4	39	as	as	ADV
ecj-11500	4	40	well	well	ADV
ecj-11500	4	41	as	as	ADP
ecj-11500	4	42	the	the	DET
ecj-11500	4	43	use	use	NOUN
ecj-11500	4	44	of	of	ADP
ecj-11500	4	45	activated	activate	VERB
ecj-11500	4	46	four	four	NUM
ecj-11500	4	47	-	-	PUNCT
ecj-11500	4	48	factor	factor	NOUN
ecj-11500	4	49	pcc	pcc	NOUN
ecj-11500	4	50	(	(	PUNCT
ecj-11500	4	51	feiba	feiba	PROPN
ecj-11500	4	52	)	)	PUNCT
ecj-11500	4	53	.	.	PUNCT
ecj-11500	5	1	the	the	DET
ecj-11500	5	2	specific	specific	ADJ
ecj-11500	5	3	rotem	rotem	NOUN
ecj-11500	5	4	tests	test	NOUN
ecj-11500	5	5	,	,	PUNCT
ecj-11500	5	6	intem	intem	NOUN
ecj-11500	5	7	and	and	CCONJ
ecj-11500	5	8	extem	extem	NOUN
ecj-11500	5	9	,	,	PUNCT
ecj-11500	5	10	further	far	ADV
ecj-11500	5	11	enhance	enhance	VERB
ecj-11500	5	12	our	our	PRON
ecj-11500	5	13	understanding	understanding	NOUN
ecj-11500	5	14	of	of	ADP
ecj-11500	5	15	the	the	DET
ecj-11500	5	16	intrinsic	intrinsic	ADJ
ecj-11500	5	17	and	and	CCONJ
ecj-11500	5	18	extrinsic	extrinsic	ADJ
ecj-11500	5	19	coagulation	coagulation	NOUN
ecj-11500	5	20	pathways	pathway	NOUN
ecj-11500	5	21	.	.	PUNCT
ecj-11500	6	1	moreover	moreover	ADV
ecj-11500	6	2	,	,	PUNCT
ecj-11500	6	3	the	the	DET
ecj-11500	6	4	use	use	NOUN
ecj-11500	6	5	of	of	ADP
ecj-11500	6	6	tranexamic	tranexamic	ADJ
ecj-11500	6	7	acid	acid	NOUN
ecj-11500	6	8	(	(	PUNCT
ecj-11500	6	9	txa	txa	PROPN
ecj-11500	6	10	)	)	PUNCT
ecj-11500	6	11	and	and	CCONJ
ecj-11500	6	12	fibrinogen	fibrinogen	NOUN
ecj-11500	6	13	,	,	PUNCT
ecj-11500	6	14	guided	guide	VERB
ecj-11500	6	15	by	by	ADP
ecj-11500	6	16	these	these	DET
ecj-11500	6	17	visco	visco	ADJ
ecj-11500	6	18	-	-	ADJ
ecj-11500	6	19	elastic	elastic	ADJ
ecj-11500	6	20	tests	test	NOUN
ecj-11500	6	21	,	,	PUNCT
ecj-11500	6	22	has	have	AUX
ecj-11500	6	23	shown	show	VERB
ecj-11500	6	24	promise	promise	NOUN
ecj-11500	6	25	in	in	ADP
ecj-11500	6	26	trauma	trauma	NOUN
ecj-11500	6	27	patients	patient	NOUN
ecj-11500	6	28	.	.	PUNCT
ecj-11500	7	1	txa	txa	PROPN
ecj-11500	7	2	has	have	AUX
ecj-11500	7	3	been	be	AUX
ecj-11500	7	4	associated	associate	VERB
ecj-11500	7	5	with	with	ADP
ecj-11500	7	6	survival	survival	NOUN
ecj-11500	7	7	benefit	benefit	NOUN
ecj-11500	7	8	when	when	SCONJ
ecj-11500	7	9	administered	administer	VERB
ecj-11500	7	10	immediately	immediately	ADV
ecj-11500	7	11	or	or	CCONJ
ecj-11500	7	12	within	within	ADP
ecj-11500	7	13	3	3	NUM
ecj-11500	7	14	hours	hour	NOUN
ecj-11500	7	15	of	of	ADP
ecj-11500	7	16	injury	injury	NOUN
ecj-11500	7	17	.	.	PUNCT
ecj-11500	8	1	fibrinogen	fibrinogen	NOUN
ecj-11500	8	2	,	,	PUNCT
ecj-11500	8	3	a	a	DET
ecj-11500	8	4	key	key	ADJ
ecj-11500	8	5	factor	factor	NOUN
ecj-11500	8	6	in	in	ADP
ecj-11500	8	7	clot	clot	NOUN
ecj-11500	8	8	formation	formation	NOUN
ecj-11500	8	9	,	,	PUNCT
ecj-11500	8	10	can	can	AUX
ecj-11500	8	11	be	be	AUX
ecj-11500	8	12	monitored	monitor	VERB
ecj-11500	8	13	and	and	CCONJ
ecj-11500	8	14	supplemented	supplement	VERB
ecj-11500	8	15	as	as	SCONJ
ecj-11500	8	16	needed	need	VERB
ecj-11500	8	17	to	to	PART
ecj-11500	8	18	optimize	optimize	VERB
ecj-11500	8	19	hemostasis	hemostasis	NOUN
ecj-11500	8	20	.	.	PUNCT
ecj-11500	9	1	in	in	ADP
ecj-11500	9	2	conclusion	conclusion	NOUN
ecj-11500	9	3	,	,	PUNCT
ecj-11500	9	4	the	the	DET
ecj-11500	9	5	practice	practice	NOUN
ecj-11500	9	6	of	of	ADP
ecj-11500	9	7	precision	precision	NOUN
ecj-11500	9	8	medicine	medicine	NOUN
ecj-11500	9	9	,	,	PUNCT
ecj-11500	9	10	with	with	ADP
ecj-11500	9	11	the	the	DET
ecj-11500	9	12	aid	aid	NOUN
ecj-11500	9	13	of	of	ADP
ecj-11500	9	14	teg	teg	PROPN
ecj-11500	9	15	and	and	CCONJ
ecj-11500	9	16	rotem	rotem	PROPN
ecj-11500	9	17	,	,	PUNCT
ecj-11500	9	18	offers	offer	VERB
ecj-11500	9	19	the	the	DET
ecj-11500	9	20	potential	potential	NOUN
ecj-11500	9	21	to	to	PART
ecj-11500	9	22	enhance	enhance	VERB
ecj-11500	9	23	the	the	DET
ecj-11500	9	24	safety	safety	NOUN
ecj-11500	9	25	and	and	CCONJ
ecj-11500	9	26	efficacy	efficacy	NOUN
ecj-11500	9	27	of	of	ADP
ecj-11500	9	28	pcc	pcc	NOUN
ecj-11500	9	29	therapy	therapy	NOUN
ecj-11500	9	30	,	,	PUNCT
ecj-11500	9	31	txa	txa	PROPN
ecj-11500	9	32	administration	administration	NOUN
ecj-11500	9	33	,	,	PUNCT
ecj-11500	9	34	and	and	CCONJ
ecj-11500	9	35	fibrinogen	fibrinogen	NOUN
ecj-11500	9	36	supplementation	supplementation	NOUN
ecj-11500	9	37	.	.	PUNCT
ecj-11500	10	1	these	these	DET
ecj-11500	10	2	tools	tool	NOUN
ecj-11500	10	3	are	be	AUX
ecj-11500	10	4	invaluable	invaluable	ADJ
ecj-11500	10	5	in	in	ADP
ecj-11500	10	6	tailoring	tailor	VERB
ecj-11500	10	7	therapy	therapy	NOUN
ecj-11500	10	8	to	to	ADP
ecj-11500	10	9	the	the	DET
ecj-11500	10	10	specific	specific	ADJ
ecj-11500	10	11	needs	need	NOUN
ecj-11500	10	12	of	of	ADP
ecj-11500	10	13	each	each	DET
ecj-11500	10	14	patient	patient	NOUN
ecj-11500	10	15	,	,	PUNCT
ecj-11500	10	16	potentially	potentially	ADV
ecj-11500	10	17	optimizing	optimize	VERB
ecj-11500	10	18	patient	patient	ADJ
ecj-11500	10	19	outcomes	outcome	NOUN
ecj-11500	10	20	and	and	CCONJ
ecj-11500	10	21	minimizing	minimize	VERB
ecj-11500	10	22	the	the	DET
ecj-11500	10	23	risk	risk	NOUN
ecj-11500	10	24	of	of	ADP
ecj-11500	10	25	adverse	adverse	ADJ
ecj-11500	10	26	events	event	NOUN
ecj-11500	10	27	.	.	PUNCT
ecj-11500	11	1	introduction	introduction	NOUN
ecj-11500	11	2	prothrombin	prothrombin	NOUN
ecj-11500	11	3	complex	complex	ADJ
ecj-11500	11	4	concentrate	concentrate	NOUN
ecj-11500	11	5	(	(	PUNCT
ecj-11500	11	6	pcc	pcc	NOUN
ecj-11500	11	7	)	)	PUNCT
ecj-11500	11	8	is	be	AUX
ecj-11500	11	9	a	a	DET
ecj-11500	11	10	critical	critical	ADJ
ecj-11500	11	11	therapeutic	therapeutic	ADJ
ecj-11500	11	12	agent	agent	NOUN
ecj-11500	11	13	used	use	VERB
ecj-11500	11	14	in	in	ADP
ecj-11500	11	15	the	the	DET
ecj-11500	11	16	management	management	NOUN
ecj-11500	11	17	of	of	ADP
ecj-11500	11	18	bleeding	bleed	VERB
ecj-11500	11	19	disorders.1	disorders.1	NOUN
ecj-11500	11	20	it	it	PRON
ecj-11500	11	21	is	be	AUX
ecj-11500	11	22	a	a	DET
ecj-11500	11	23	correspondence	correspondence	NOUN
ecj-11500	11	24	:	:	PUNCT
ecj-11500	11	25	iacopo	iacopo	PROPN
ecj-11500	11	26	cappellini	cappellini	PROPN
ecj-11500	11	27	,	,	PUNCT
ecj-11500	11	28	department	department	NOUN
ecj-11500	11	29	of	of	ADP
ecj-11500	11	30	emergency	emergency	NOUN
ecj-11500	11	31	and	and	CCONJ
ecj-11500	11	32	critical	critical	ADJ
ecj-11500	11	33	care	care	NOUN
ecj-11500	11	34	medicine	medicine	NOUN
ecj-11500	11	35	,	,	PUNCT
ecj-11500	11	36	azienda	azienda	PROPN
ecj-11500	11	37	usl	usl	PROPN
ecj-11500	11	38	toscana	toscana	PROPN
ecj-11500	11	39	centro	centro	PROPN
ecj-11500	11	40	,	,	PUNCT
ecj-11500	11	41	via	via	ADP
ecj-11500	11	42	suor	suor	PROPN
ecj-11500	11	43	niccolina	niccolina	PROPN
ecj-11500	11	44	infermiera	infermiera	PROPN
ecj-11500	11	45	20	20	NUM
ecj-11500	11	46	,	,	PUNCT
ecj-11500	11	47	prato	prato	PROPN
ecj-11500	11	48	,	,	PUNCT
ecj-11500	11	49	italy	italy	PROPN
ecj-11500	11	50	.	.	PUNCT
ecj-11500	12	1	e	e	X
ecj-11500	12	2	-	-	NOUN
ecj-11500	12	3	mail	mail	NOUN
ecj-11500	12	4	:	:	PUNCT
ecj-11500	12	5	iacopo.cappellini@uslcentro.toscana.it	iacopo.cappellini@uslcentro.toscana.it	PROPN
ecj-11500	12	6	key	key	ADJ
ecj-11500	12	7	words	word	NOUN
ecj-11500	12	8	:	:	PUNCT
ecj-11500	12	9	prothrombin	prothrombin	ADJ
ecj-11500	12	10	complex	complex	ADJ
ecj-11500	12	11	concentrates	concentrate	NOUN
ecj-11500	12	12	;	;	PUNCT
ecj-11500	12	13	viscoelastic	viscoelastic	NOUN
ecj-11500	12	14	tests	test	NOUN
ecj-11500	12	15	;	;	PUNCT
ecj-11500	12	16	coagulation	coagulation	NOUN
ecj-11500	12	17	disorder	disorder	NOUN
ecj-11500	12	18	.	.	PUNCT
ecj-11500	13	1	contributions	contribution	NOUN
ecj-11500	13	2	:	:	PUNCT
ecj-11500	13	3	ic	ic	PROPN
ecj-11500	13	4	and	and	CCONJ
ecj-11500	13	5	fl	fl	PROPN
ecj-11500	13	6	are	be	AUX
ecj-11500	13	7	the	the	DET
ecj-11500	13	8	principal	principal	ADJ
ecj-11500	13	9	investigators	investigator	NOUN
ecj-11500	13	10	and	and	CCONJ
ecj-11500	13	11	conceived	conceive	VERB
ecj-11500	13	12	this	this	DET
ecj-11500	13	13	study	study	NOUN
ecj-11500	13	14	,	,	PUNCT
ecj-11500	13	15	and	and	CCONJ
ecj-11500	13	16	collected	collect	VERB
ecj-11500	13	17	the	the	DET
ecj-11500	13	18	literature	literature	NOUN
ecj-11500	13	19	;	;	PUNCT
ecj-11500	13	20	ic	ic	PROPN
ecj-11500	13	21	,	,	PUNCT
ecj-11500	13	22	fl	fl	PROPN
ecj-11500	13	23	,	,	PUNCT
ecj-11500	13	24	gc	gc	PROPN
ecj-11500	13	25	and	and	CCONJ
ecj-11500	13	26	sm	sm	PROPN
ecj-11500	13	27	wrote	write	VERB
ecj-11500	13	28	this	this	DET
ecj-11500	13	29	manuscript	manuscript	NOUN
ecj-11500	13	30	.	.	PUNCT
ecj-11500	14	1	conflict	conflict	NOUN
ecj-11500	14	2	of	of	ADP
ecj-11500	14	3	interest	interest	NOUN
ecj-11500	14	4	:	:	PUNCT
ecj-11500	14	5	the	the	DET
ecj-11500	14	6	authors	author	NOUN
ecj-11500	14	7	declare	declare	VERB
ecj-11500	14	8	no	no	DET
ecj-11500	14	9	potential	potential	ADJ
ecj-11500	14	10	conflict	conflict	NOUN
ecj-11500	14	11	of	of	ADP
ecj-11500	14	12	interest	interest	NOUN
ecj-11500	14	13	,	,	PUNCT
ecj-11500	14	14	and	and	CCONJ
ecj-11500	14	15	all	all	DET
ecj-11500	14	16	authors	author	NOUN
ecj-11500	14	17	confirm	confirm	VERB
ecj-11500	14	18	accuracy	accuracy	NOUN
ecj-11500	14	19	.	.	PUNCT
ecj-11500	15	1	ethics	ethic	NOUN
ecj-11500	15	2	approval	approval	NOUN
ecj-11500	15	3	:	:	PUNCT
ecj-11500	15	4	not	not	PART
ecj-11500	15	5	applicable	applicable	ADJ
ecj-11500	15	6	.	.	PUNCT
ecj-11500	16	1	informed	informed	ADJ
ecj-11500	16	2	consent	consent	NOUN
ecj-11500	16	3	:	:	PUNCT
ecj-11500	16	4	not	not	PART
ecj-11500	16	5	applicable	applicable	ADJ
ecj-11500	16	6	.	.	PUNCT
ecj-11500	17	1	patient	patient	ADJ
ecj-11500	17	2	consent	consent	NOUN
ecj-11500	17	3	for	for	ADP
ecj-11500	17	4	publication	publication	NOUN
ecj-11500	17	5	:	:	PUNCT
ecj-11500	17	6	not	not	PART
ecj-11500	17	7	applicable	applicable	ADJ
ecj-11500	17	8	.	.	PUNCT
ecj-11500	18	1	availability	availability	NOUN
ecj-11500	18	2	of	of	ADP
ecj-11500	18	3	data	datum	NOUN
ecj-11500	18	4	and	and	CCONJ
ecj-11500	18	5	materials	material	NOUN
ecj-11500	18	6	:	:	PUNCT
ecj-11500	18	7	all	all	DET
ecj-11500	18	8	data	datum	NOUN
ecj-11500	18	9	generated	generate	VERB
ecj-11500	18	10	or	or	CCONJ
ecj-11500	18	11	analyzed	analyze	VERB
ecj-11500	18	12	during	during	ADP
ecj-11500	18	13	this	this	DET
ecj-11500	18	14	study	study	NOUN
ecj-11500	18	15	are	be	AUX
ecj-11500	18	16	included	include	VERB
ecj-11500	18	17	in	in	ADP
ecj-11500	18	18	this	this	DET
ecj-11500	18	19	published	publish	VERB
ecj-11500	18	20	article	article	NOUN
ecj-11500	18	21	.	.	PUNCT
ecj-11500	19	1	acknowledgements	acknowledgement	NOUN
ecj-11500	19	2	:	:	PUNCT
ecj-11500	19	3	large	large	ADJ
ecj-11500	19	4	language	language	NOUN
ecj-11500	19	5	models	model	NOUN
ecj-11500	19	6	(	(	PUNCT
ecj-11500	19	7	llms	llm	NOUN
ecj-11500	19	8	)	)	PUNCT
ecj-11500	19	9	were	be	AUX
ecj-11500	19	10	used	use	VERB
ecj-11500	19	11	in	in	ADP
ecj-11500	19	12	order	order	NOUN
ecj-11500	19	13	to	to	PART
ecj-11500	19	14	edit	edit	VERB
ecj-11500	19	15	the	the	DET
ecj-11500	19	16	present	present	ADJ
ecj-11500	19	17	manuscript	manuscript	NOUN
ecj-11500	19	18	.	.	PUNCT
ecj-11500	20	1	received	receive	VERB
ecj-11500	20	2	for	for	ADP
ecj-11500	20	3	publication	publication	NOUN
ecj-11500	20	4	:	:	PUNCT
ecj-11500	20	5	31	31	NUM
ecj-11500	20	6	may	may	PROPN
ecj-11500	20	7	2023	2023	NUM
ecj-11500	20	8	.	.	PUNCT
ecj-11500	21	1	accepted	accept	VERB
ecj-11500	21	2	for	for	ADP
ecj-11500	21	3	publication	publication	NOUN
ecj-11500	21	4	:	:	PUNCT
ecj-11500	21	5	21	21	NUM
ecj-11500	21	6	september	september	PROPN
ecj-11500	21	7	2023	2023	NUM
ecj-11500	21	8	.	.	PUNCT
ecj-11500	22	1	early	early	ADJ
ecj-11500	22	2	view	view	NOUN
ecj-11500	22	3	:	:	PUNCT
ecj-11500	22	4	3	3	NUM
ecj-11500	22	5	october	october	PROPN
ecj-11500	22	6	2023	2023	NUM
ecj-11500	22	7	.	.	PUNCT
ecj-11500	23	1	this	this	DET
ecj-11500	23	2	work	work	NOUN
ecj-11500	23	3	is	be	AUX
ecj-11500	23	4	licensed	license	VERB
ecj-11500	23	5	under	under	ADP
ecj-11500	23	6	a	a	DET
ecj-11500	23	7	creative	creative	ADJ
ecj-11500	23	8	commons	common	NOUN
ecj-11500	23	9	attribution	attribution	NOUN
ecj-11500	23	10	4.0	4.0	NUM
ecj-11500	23	11	license	license	NOUN
ecj-11500	23	12	(	(	PUNCT
ecj-11500	23	13	by	by	ADP
ecj-11500	23	14	-	-	PUNCT
ecj-11500	23	15	nc	nc	PROPN
ecj-11500	23	16	4.0	4.0	NUM
ecj-11500	23	17	)	)	PUNCT
ecj-11500	23	18	.	.	PUNCT
ecj-11500	24	1	©	©	PROPN
ecj-11500	24	2	copyright	copyright	NOUN
ecj-11500	24	3	:	:	PUNCT
ecj-11500	24	4	the	the	DET
ecj-11500	24	5	author(s	author(s	PROPN
ecj-11500	24	6	)	)	PUNCT
ecj-11500	24	7	,	,	PUNCT
ecj-11500	24	8	2023	2023	NUM
ecj-11500	24	9	licensee	licensee	NOUN
ecj-11500	24	10	pagepress	pagepress	NOUN
ecj-11500	24	11	,	,	PUNCT
ecj-11500	24	12	italy	italy	PROPN
ecj-11500	24	13	emergency	emergency	PROPN
ecj-11500	24	14	care	care	PROPN
ecj-11500	24	15	journal	journal	PROPN
ecj-11500	24	16	2023	2023	NUM
ecj-11500	24	17	;	;	PUNCT
ecj-11500	24	18	19:11500	19:11500	NUM
ecj-11500	24	19	doi:10.4081	doi:10.4081	NOUN
ecj-11500	24	20	/	/	SYM
ecj-11500	24	21	ecj.2023.11500	ecj.2023.11500	PROPN
ecj-11500	24	22	publisher	publisher	NOUN
ecj-11500	24	23	's	's	PART
ecj-11500	24	24	note	note	NOUN
ecj-11500	24	25	:	:	PUNCT
ecj-11500	24	26	all	all	DET
ecj-11500	24	27	claims	claim	NOUN
ecj-11500	24	28	expressed	express	VERB
ecj-11500	24	29	in	in	ADP
ecj-11500	24	30	this	this	DET
ecj-11500	24	31	article	article	NOUN
ecj-11500	24	32	are	be	AUX
ecj-11500	24	33	solely	solely	ADV
ecj-11500	24	34	those	those	PRON
ecj-11500	24	35	of	of	ADP
ecj-11500	24	36	the	the	DET
ecj-11500	24	37	authors	author	NOUN
ecj-11500	24	38	and	and	CCONJ
ecj-11500	24	39	do	do	AUX
ecj-11500	24	40	not	not	PART
ecj-11500	24	41	necessarily	necessarily	ADV
ecj-11500	24	42	represent	represent	VERB
ecj-11500	24	43	those	those	PRON
ecj-11500	24	44	of	of	ADP
ecj-11500	24	45	their	their	PRON
ecj-11500	24	46	affiliated	affiliated	ADJ
ecj-11500	24	47	organizations	organization	NOUN
ecj-11500	24	48	,	,	PUNCT
ecj-11500	24	49	or	or	CCONJ
ecj-11500	24	50	those	those	PRON
ecj-11500	24	51	of	of	ADP
ecj-11500	24	52	the	the	DET
ecj-11500	24	53	publisher	publisher	NOUN
ecj-11500	24	54	,	,	PUNCT
ecj-11500	24	55	the	the	DET
ecj-11500	24	56	editors	editor	NOUN
ecj-11500	24	57	and	and	CCONJ
ecj-11500	24	58	the	the	DET
ecj-11500	24	59	reviewers	reviewer	NOUN
ecj-11500	24	60	.	.	PUNCT
ecj-11500	25	1	any	any	DET
ecj-11500	25	2	product	product	NOUN
ecj-11500	25	3	that	that	PRON
ecj-11500	25	4	may	may	AUX
ecj-11500	25	5	be	be	AUX
ecj-11500	25	6	evaluated	evaluate	VERB
ecj-11500	25	7	in	in	ADP
ecj-11500	25	8	this	this	DET
ecj-11500	25	9	article	article	NOUN
ecj-11500	25	10	or	or	CCONJ
ecj-11500	25	11	claim	claim	NOUN
ecj-11500	25	12	that	that	PRON
ecj-11500	25	13	may	may	AUX
ecj-11500	25	14	be	be	AUX
ecj-11500	25	15	made	make	VERB
ecj-11500	25	16	by	by	ADP
ecj-11500	25	17	its	its	PRON
ecj-11500	25	18	manufacturer	manufacturer	NOUN
ecj-11500	25	19	is	be	AUX
ecj-11500	25	20	not	not	PART
ecj-11500	25	21	guaranteed	guarantee	VERB
ecj-11500	25	22	or	or	CCONJ
ecj-11500	25	23	endorsed	endorse	VERB
ecj-11500	25	24	by	by	ADP
ecj-11500	25	25	the	the	DET
ecj-11500	25	26	publisher	publisher	NOUN
ecj-11500	25	27	.	.	PUNCT
ecj-11500	26	1	highlights	highlight	VERB
ecj-11500	26	2	real	real	ADJ
ecj-11500	26	3	-	-	PUNCT
ecj-11500	26	4	time	time	NOUN
ecj-11500	26	5	coagulation	coagulation	NOUN
ecj-11500	26	6	assessment	assessment	NOUN
ecj-11500	26	7	:	:	PUNCT
ecj-11500	26	8	teg	teg	PROPN
ecj-11500	26	9	and	and	CCONJ
ecj-11500	26	10	rotem	rotem	PROPN
ecj-11500	26	11	provide	provide	VERB
ecj-11500	26	12	real	real	ADJ
ecj-11500	26	13	-	-	PUNCT
ecj-11500	26	14	time	time	NOUN
ecj-11500	26	15	and	and	CCONJ
ecj-11500	26	16	dynamic	dynamic	ADJ
ecj-11500	26	17	insights	insight	NOUN
ecj-11500	26	18	into	into	ADP
ecj-11500	26	19	a	a	DET
ecj-11500	26	20	patient	patient	NOUN
ecj-11500	26	21	's	's	PART
ecj-11500	26	22	coagulation	coagulation	NOUN
ecj-11500	26	23	status	status	NOUN
ecj-11500	26	24	,	,	PUNCT
ecj-11500	26	25	enabling	enable	VERB
ecj-11500	26	26	precise	precise	ADJ
ecj-11500	26	27	decision	decision	NOUN
ecj-11500	26	28	-	-	PUNCT
ecj-11500	26	29	making	making	NOUN
ecj-11500	26	30	in	in	ADP
ecj-11500	26	31	therapy	therapy	NOUN
ecj-11500	26	32	selection	selection	NOUN
ecj-11500	26	33	.	.	PUNCT
ecj-11500	27	1	choice	choice	NOUN
ecj-11500	27	2	of	of	ADP
ecj-11500	27	3	prothrombin	prothrombin	ADJ
ecj-11500	27	4	complex	complex	ADJ
ecj-11500	27	5	concentrate	concentrate	NOUN
ecj-11500	27	6	(	(	PUNCT
ecj-11500	27	7	pcc	pcc	NOUN
ecj-11500	27	8	):	):	PUNCT
ecj-11500	27	9	these	these	DET
ecj-11500	27	10	tests	test	NOUN
ecj-11500	27	11	guide	guide	VERB
ecj-11500	27	12	the	the	DET
ecj-11500	27	13	choice	choice	NOUN
ecj-11500	27	14	between	between	ADP
ecj-11500	27	15	three	three	NUM
ecj-11500	27	16	-	-	PUNCT
ecj-11500	27	17	factor	factor	NOUN
ecj-11500	27	18	pcc3	pcc3	NOUN
ecj-11500	27	19	and	and	CCONJ
ecj-11500	27	20	four	four	NUM
ecj-11500	27	21	factor	factor	NOUN
ecj-11500	27	22	pcc4	pcc4	PROPN
ecj-11500	27	23	,	,	PUNCT
ecj-11500	27	24	as	as	ADV
ecj-11500	27	25	well	well	ADV
ecj-11500	27	26	as	as	ADP
ecj-11500	27	27	the	the	DET
ecj-11500	27	28	use	use	NOUN
ecj-11500	27	29	of	of	ADP
ecj-11500	27	30	activated	activate	VERB
ecj-11500	27	31	four	four	NUM
ecj-11500	27	32	-	-	PUNCT
ecj-11500	27	33	factor	factor	NOUN
ecj-11500	27	34	pcc	pcc	NOUN
ecj-11500	27	35	(	(	PUNCT
ecj-11500	27	36	feiba	feiba	PROPN
ecj-11500	27	37	)	)	PUNCT
ecj-11500	27	38	,	,	PUNCT
ecj-11500	27	39	tailored	tailor	VERB
ecj-11500	27	40	to	to	ADP
ecj-11500	27	41	individual	individual	ADJ
ecj-11500	27	42	patient	patient	NOUN
ecj-11500	27	43	needs	need	NOUN
ecj-11500	27	44	.	.	PUNCT
ecj-11500	28	1	rotem	rotem	NOUN
ecj-11500	28	2	tests	test	NOUN
ecj-11500	28	3	:	:	PUNCT
ecj-11500	28	4	specific	specific	ADJ
ecj-11500	28	5	rotem	rotem	NOUN
ecj-11500	28	6	tests	test	NOUN
ecj-11500	28	7	,	,	PUNCT
ecj-11500	28	8	such	such	ADJ
ecj-11500	28	9	as	as	ADP
ecj-11500	28	10	intem	intem	NOUN
ecj-11500	28	11	and	and	CCONJ
ecj-11500	28	12	extem	extem	NOUN
ecj-11500	28	13	,	,	PUNCT
ecj-11500	28	14	enhance	enhance	VERB
ecj-11500	28	15	understanding	understanding	NOUN
ecj-11500	28	16	of	of	ADP
ecj-11500	28	17	the	the	DET
ecj-11500	28	18	intrinsic	intrinsic	ADJ
ecj-11500	28	19	and	and	CCONJ
ecj-11500	28	20	extrinsic	extrinsic	ADJ
ecj-11500	28	21	coagulation	coagulation	NOUN
ecj-11500	28	22	pathways	pathway	NOUN
ecj-11500	28	23	,	,	PUNCT
ecj-11500	28	24	aiding	aid	VERB
ecj-11500	28	25	in	in	ADP
ecj-11500	28	26	targeted	target	VERB
ecj-11500	28	27	interventions	intervention	NOUN
ecj-11500	28	28	.	.	PUNCT
ecj-11500	29	1	tranexamic	tranexamic	ADJ
ecj-11500	29	2	acid	acid	NOUN
ecj-11500	29	3	(	(	PUNCT
ecj-11500	29	4	txa	txa	PROPN
ecj-11500	29	5	):	):	PUNCT
ecj-11500	29	6	txa	txa	PROPN
ecj-11500	29	7	,	,	PUNCT
ecj-11500	29	8	administered	administer	VERB
ecj-11500	29	9	based	base	VERB
ecj-11500	29	10	on	on	ADP
ecj-11500	29	11	visco	visco	ADJ
ecj-11500	29	12	elastic	elastic	ADJ
ecj-11500	29	13	tests	test	NOUN
ecj-11500	29	14	,	,	PUNCT
ecj-11500	29	15	has	have	AUX
ecj-11500	29	16	shown	show	VERB
ecj-11500	29	17	survival	survival	NOUN
ecj-11500	29	18	benefits	benefit	NOUN
ecj-11500	29	19	when	when	SCONJ
ecj-11500	29	20	given	give	VERB
ecj-11500	29	21	promptly	promptly	ADV
ecj-11500	29	22	,	,	PUNCT
ecj-11500	29	23	particularly	particularly	ADV
ecj-11500	29	24	within	within	ADP
ecj-11500	29	25	3	3	NUM
ecj-11500	29	26	hours	hour	NOUN
ecj-11500	29	27	of	of	ADP
ecj-11500	29	28	injury	injury	NOUN
ecj-11500	29	29	.	.	PUNCT
ecj-11500	30	1	fibrinogen	fibrinogen	NOUN
ecj-11500	30	2	optimization	optimization	NOUN
ecj-11500	30	3	:	:	PUNCT
ecj-11500	30	4	monitoring	monitoring	NOUN
ecj-11500	30	5	and	and	CCONJ
ecj-11500	30	6	supplementation	supplementation	NOUN
ecj-11500	30	7	of	of	ADP
ecj-11500	30	8	fibrinogen	fibrinogen	NOUN
ecj-11500	30	9	,	,	PUNCT
ecj-11500	30	10	a	a	DET
ecj-11500	30	11	crucial	crucial	ADJ
ecj-11500	30	12	clotting	clotting	NOUN
ecj-11500	30	13	factor	factor	NOUN
ecj-11500	30	14	,	,	PUNCT
ecj-11500	30	15	is	be	AUX
ecj-11500	30	16	facilitated	facilitate	VERB
ecj-11500	30	17	by	by	ADP
ecj-11500	30	18	visco	visco	ADJ
ecj-11500	30	19	elastic	elastic	ADJ
ecj-11500	30	20	tests	test	NOUN
ecj-11500	30	21	,	,	PUNCT
ecj-11500	30	22	ensuring	ensure	VERB
ecj-11500	30	23	hemostasis	hemostasis	NOUN
ecj-11500	30	24	is	be	AUX
ecj-11500	30	25	optimized	optimize	VERB
ecj-11500	30	26	for	for	ADP
ecj-11500	30	27	each	each	DET
ecj-11500	30	28	patient	patient	NOUN
ecj-11500	30	29	.	.	PUNCT
ecj-11500	31	1	enhancing	enhance	VERB
ecj-11500	31	2	safety	safety	NOUN
ecj-11500	31	3	and	and	CCONJ
ecj-11500	31	4	efficacy	efficacy	NOUN
ecj-11500	31	5	:	:	PUNCT
ecj-11500	31	6	precision	precision	NOUN
ecj-11500	31	7	medicine	medicine	NOUN
ecj-11500	31	8	,	,	PUNCT
ecj-11500	31	9	with	with	ADP
ecj-11500	31	10	teg	teg	PROPN
ecj-11500	31	11	and	and	CCONJ
ecj-11500	31	12	rotem	rotem	PROPN
ecj-11500	31	13	,	,	PUNCT
ecj-11500	31	14	has	have	VERB
ecj-11500	31	15	the	the	DET
ecj-11500	31	16	potential	potential	NOUN
ecj-11500	31	17	to	to	PART
ecj-11500	31	18	enhance	enhance	VERB
ecj-11500	31	19	the	the	DET
ecj-11500	31	20	safety	safety	NOUN
ecj-11500	31	21	and	and	CCONJ
ecj-11500	31	22	effectiveness	effectiveness	NOUN
ecj-11500	31	23	of	of	ADP
ecj-11500	31	24	pcc	pcc	NOUN
ecj-11500	31	25	therapy	therapy	NOUN
ecj-11500	31	26	,	,	PUNCT
ecj-11500	31	27	txa	txa	PROPN
ecj-11500	31	28	administration	administration	NOUN
ecj-11500	31	29	,	,	PUNCT
ecj-11500	31	30	and	and	CCONJ
ecj-11500	31	31	fibrinogen	fibrinogen	NOUN
ecj-11500	31	32	supplementation	supplementation	NOUN
ecj-11500	31	33	.	.	PUNCT
ecj-11500	32	1	tailored	tailor	VERB
ecj-11500	32	2	therapy	therapy	NOUN
ecj-11500	32	3	:	:	PUNCT
ecj-11500	32	4	these	these	DET
ecj-11500	32	5	tools	tool	NOUN
ecj-11500	32	6	enable	enable	VERB
ecj-11500	32	7	tailoring	tailoring	NOUN
ecj-11500	32	8	of	of	ADP
ecj-11500	32	9	therapy	therapy	NOUN
ecj-11500	32	10	to	to	PART
ecj-11500	32	11	meet	meet	VERB
ecj-11500	32	12	the	the	DET
ecj-11500	32	13	specific	specific	ADJ
ecj-11500	32	14	needs	need	NOUN
ecj-11500	32	15	of	of	ADP
ecj-11500	32	16	each	each	DET
ecj-11500	32	17	patient	patient	NOUN
ecj-11500	32	18	,	,	PUNCT
ecj-11500	32	19	which	which	PRON
ecj-11500	32	20	can	can	AUX
ecj-11500	32	21	ultimately	ultimately	ADV
ecj-11500	32	22	optimize	optimize	VERB
ecj-11500	32	23	patient	patient	ADJ
ecj-11500	32	24	outcomes	outcome	NOUN
ecj-11500	32	25	and	and	CCONJ
ecj-11500	32	26	reduce	reduce	VERB
ecj-11500	32	27	the	the	DET
ecj-11500	32	28	risk	risk	NOUN
ecj-11500	32	29	of	of	ADP
ecj-11500	32	30	adverse	adverse	ADJ
ecj-11500	32	31	events	event	NOUN
ecj-11500	32	32	.	.	PUNCT
ecj-11500	33	1	non	non	ADJ
ecj-11500	33	2	-co	-co	PROPN
ecj-11500	33	3	mmerc	mmerc	PROPN
ecj-11500	33	4	ial	ial	PROPN
ecj-11500	33	5	us	us	PROPN
ecj-11500	33	6	e	e	NOUN
ecj-11500	33	7	o	o	NOUN
ecj-11500	33	8	nly	nly	ADV
ecj-11500	33	9	blood	blood	NOUN
ecj-11500	33	10	product	product	NOUN
ecj-11500	33	11	that	that	PRON
ecj-11500	33	12	contains	contain	VERB
ecj-11500	33	13	concentrated	concentrated	ADJ
ecj-11500	33	14	amounts	amount	NOUN
ecj-11500	33	15	of	of	ADP
ecj-11500	33	16	several	several	ADJ
ecj-11500	33	17	essential	essential	ADJ
ecj-11500	33	18	blood	blood	NOUN
ecj-11500	33	19	clotting	clot	VERB
ecj-11500	33	20	factors	factor	NOUN
ecj-11500	33	21	,	,	PUNCT
ecj-11500	33	22	specifically	specifically	ADV
ecj-11500	33	23	factors	factor	NOUN
ecj-11500	33	24	ii	ii	PROPN
ecj-11500	33	25	,	,	PUNCT
ecj-11500	33	26	vii	vii	PROPN
ecj-11500	33	27	,	,	PUNCT
ecj-11500	33	28	ix	ix	ADV
ecj-11500	33	29	,	,	PUNCT
ecj-11500	33	30	and	and	CCONJ
ecj-11500	33	31	x	x	X
ecj-11500	33	32	in	in	ADP
ecj-11500	33	33	non	non	ADJ
ecj-11500	33	34	-	-	ADJ
ecj-11500	33	35	activated	activated	ADJ
ecj-11500	33	36	form	form	NOUN
ecj-11500	33	37	.	.	PUNCT
ecj-11500	34	1	pcc	pcc	NOUN
ecj-11500	34	2	is	be	AUX
ecj-11500	34	3	available	available	ADJ
ecj-11500	34	4	in	in	ADP
ecj-11500	34	5	two	two	NUM
ecj-11500	34	6	forms	form	NOUN
ecj-11500	34	7	:	:	PUNCT
ecj-11500	34	8	three	three	NUM
ecj-11500	34	9	-	-	PUNCT
ecj-11500	34	10	factor	factor	NOUN
ecj-11500	34	11	pcc	pcc	NOUN
ecj-11500	34	12	(	(	PUNCT
ecj-11500	34	13	pcc3	pcc3	PROPN
ecj-11500	34	14	)	)	PUNCT
ecj-11500	34	15	,	,	PUNCT
ecj-11500	34	16	which	which	PRON
ecj-11500	34	17	contains	contain	VERB
ecj-11500	34	18	factors	factor	NOUN
ecj-11500	34	19	ii	ii	PROPN
ecj-11500	34	20	,	,	PUNCT
ecj-11500	34	21	ix	ix	ADV
ecj-11500	34	22	,	,	PUNCT
ecj-11500	34	23	and	and	CCONJ
ecj-11500	34	24	x	x	NOUN
ecj-11500	34	25	,	,	PUNCT
ecj-11500	34	26	and	and	CCONJ
ecj-11500	34	27	four	four	NUM
ecj-11500	34	28	-	-	PUNCT
ecj-11500	34	29	factor	factor	NOUN
ecj-11500	34	30	pcc	pcc	NOUN
ecj-11500	34	31	(	(	PUNCT
ecj-11500	34	32	pcc4	pcc4	PROPN
ecj-11500	34	33	)	)	PUNCT
ecj-11500	34	34	,	,	PUNCT
ecj-11500	34	35	which	which	PRON
ecj-11500	34	36	additionally	additionally	ADV
ecj-11500	34	37	includes	include	VERB
ecj-11500	34	38	factor	factor	NOUN
ecj-11500	34	39	vii	vii	PROPN
ecj-11500	34	40	.	.	PUNCT
ecj-11500	35	1	these	these	DET
ecj-11500	35	2	agents	agent	NOUN
ecj-11500	35	3	are	be	AUX
ecj-11500	35	4	primarily	primarily	ADV
ecj-11500	35	5	used	use	VERB
ecj-11500	35	6	for	for	ADP
ecj-11500	35	7	the	the	DET
ecj-11500	35	8	rapid	rapid	ADJ
ecj-11500	35	9	reversal	reversal	NOUN
ecj-11500	35	10	of	of	ADP
ecj-11500	35	11	anticoagulation	anticoagulation	NOUN
ecj-11500	35	12	in	in	ADP
ecj-11500	35	13	patients	patient	NOUN
ecj-11500	35	14	with	with	ADP
ecj-11500	35	15	major	major	ADJ
ecj-11500	35	16	bleeding	bleeding	NOUN
ecj-11500	35	17	or	or	CCONJ
ecj-11500	35	18	prior	prior	ADV
ecj-11500	35	19	to	to	ADP
ecj-11500	35	20	emergency	emergency	NOUN
ecj-11500	35	21	surgery.2	surgery.2	NOUN
ecj-11500	35	22	the	the	DET
ecj-11500	35	23	choice	choice	NOUN
ecj-11500	35	24	between	between	ADP
ecj-11500	35	25	pcc3	pcc3	NOUN
ecj-11500	35	26	and	and	CCONJ
ecj-11500	35	27	pcc4	pcc4	PROPN
ecj-11500	35	28	is	be	AUX
ecj-11500	35	29	often	often	ADV
ecj-11500	35	30	dictated	dictate	VERB
ecj-11500	35	31	by	by	ADP
ecj-11500	35	32	the	the	DET
ecj-11500	35	33	clinical	clinical	ADJ
ecj-11500	35	34	context	context	NOUN
ecj-11500	35	35	,	,	PUNCT
ecj-11500	35	36	the	the	DET
ecj-11500	35	37	specific	specific	ADJ
ecj-11500	35	38	coagulation	coagulation	NOUN
ecj-11500	35	39	factor	factor	NOUN
ecj-11500	35	40	deficiencies	deficiency	NOUN
ecj-11500	35	41	present	present	ADJ
ecj-11500	35	42	,	,	PUNCT
ecj-11500	35	43	and	and	CCONJ
ecj-11500	35	44	the	the	DET
ecj-11500	35	45	risk	risk	NOUN
ecj-11500	35	46	of	of	ADP
ecj-11500	35	47	potential	potential	ADJ
ecj-11500	35	48	adverse	adverse	ADJ
ecj-11500	35	49	events.2	events.2	PROPN
ecj-11500	35	50	recent	recent	ADJ
ecj-11500	35	51	studies	study	NOUN
ecj-11500	35	52	have	have	AUX
ecj-11500	35	53	shown	show	VERB
ecj-11500	35	54	that	that	SCONJ
ecj-11500	35	55	pcc4	pcc4	PROPN
ecj-11500	35	56	may	may	AUX
ecj-11500	35	57	be	be	AUX
ecj-11500	35	58	more	more	ADV
ecj-11500	35	59	effective	effective	ADJ
ecj-11500	35	60	in	in	ADP
ecj-11500	35	61	achieving	achieve	VERB
ecj-11500	35	62	target	target	NOUN
ecj-11500	35	63	inr	inr	NOUN
ecj-11500	35	64	levels	level	NOUN
ecj-11500	35	65	in	in	ADP
ecj-11500	35	66	patients	patient	NOUN
ecj-11500	35	67	requiring	require	VERB
ecj-11500	35	68	emergent	emergent	ADJ
ecj-11500	35	69	warfarin	warfarin	NOUN
ecj-11500	35	70	reversal	reversal	NOUN
ecj-11500	35	71	,	,	PUNCT
ecj-11500	35	72	suggesting	suggest	VERB
ecj-11500	35	73	a	a	DET
ecj-11500	35	74	potential	potential	ADJ
ecj-11500	35	75	advantage	advantage	NOUN
ecj-11500	35	76	over	over	ADP
ecj-11500	35	77	pcc3	pcc3	PROPN
ecj-11500	35	78	.	.	PUNCT
ecj-11500	36	1	however	however	ADV
ecj-11500	36	2	,	,	PUNCT
ecj-11500	36	3	the	the	DET
ecj-11500	36	4	risk	risk	NOUN
ecj-11500	36	5	of	of	ADP
ecj-11500	36	6	thromboembolic	thromboembolic	ADJ
ecj-11500	36	7	events	event	NOUN
ecj-11500	36	8	remains	remain	VERB
ecj-11500	36	9	a	a	DET
ecj-11500	36	10	significant	significant	ADJ
ecj-11500	36	11	concern	concern	NOUN
ecj-11500	36	12	,	,	PUNCT
ecj-11500	36	13	necessitating	necessitate	VERB
ecj-11500	36	14	careful	careful	ADJ
ecj-11500	36	15	consideration	consideration	NOUN
ecj-11500	36	16	and	and	CCONJ
ecj-11500	36	17	monitoring.1	monitoring.1	PROPN
ecj-11500	36	18	in	in	ADP
ecj-11500	36	19	this	this	DET
ecj-11500	36	20	context	context	NOUN
ecj-11500	36	21	,	,	PUNCT
ecj-11500	36	22	thromboelastometry	thromboelastometry	NOUN
ecj-11500	36	23	emerges	emerge	VERB
ecj-11500	36	24	as	as	ADP
ecj-11500	36	25	a	a	DET
ecj-11500	36	26	valuable	valuable	ADJ
ecj-11500	36	27	tool	tool	NOUN
ecj-11500	36	28	in	in	ADP
ecj-11500	36	29	guiding	guide	VERB
ecj-11500	36	30	the	the	DET
ecj-11500	36	31	use	use	NOUN
ecj-11500	36	32	of	of	ADP
ecj-11500	36	33	pcc3	pcc3	NOUN
ecj-11500	36	34	.	.	PUNCT
ecj-11500	37	1	thromboelastometry	thromboelastometry	NOUN
ecj-11500	37	2	is	be	AUX
ecj-11500	37	3	a	a	DET
ecj-11500	37	4	point	point	NOUN
ecj-11500	37	5	-	-	PUNCT
ecj-11500	37	6	of	of	ADP
ecj-11500	37	7	-	-	PUNCT
ecj-11500	37	8	care	care	NOUN
ecj-11500	37	9	coagulation	coagulation	NOUN
ecj-11500	37	10	test	test	NOUN
ecj-11500	37	11	that	that	PRON
ecj-11500	37	12	provides	provide	VERB
ecj-11500	37	13	comprehensive	comprehensive	ADJ
ecj-11500	37	14	information	information	NOUN
ecj-11500	37	15	about	about	ADP
ecj-11500	37	16	the	the	DET
ecj-11500	37	17	coagulation	coagulation	NOUN
ecj-11500	37	18	process	process	NOUN
ecj-11500	37	19	,	,	PUNCT
ecj-11500	37	20	from	from	ADP
ecj-11500	37	21	clot	clot	NOUN
ecj-11500	37	22	formation	formation	NOUN
ecj-11500	37	23	to	to	PART
ecj-11500	37	24	fibrinolysis.3	fibrinolysis.3	VERB
ecj-11500	37	25	it	it	PRON
ecj-11500	37	26	offers	offer	VERB
ecj-11500	37	27	real	real	ADJ
ecj-11500	37	28	-	-	PUNCT
ecj-11500	37	29	time	time	NOUN
ecj-11500	37	30	,	,	PUNCT
ecj-11500	37	31	dynamic	dynamic	ADJ
ecj-11500	37	32	insight	insight	NOUN
ecj-11500	37	33	into	into	ADP
ecj-11500	37	34	the	the	DET
ecj-11500	37	35	patient	patient	NOUN
ecj-11500	37	36	’s	’s	PART
ecj-11500	37	37	coagulation	coagulation	NOUN
ecj-11500	37	38	status	status	NOUN
ecj-11500	37	39	,	,	PUNCT
ecj-11500	37	40	enabling	enable	VERB
ecj-11500	37	41	personalized	personalize	VERB
ecj-11500	37	42	,	,	PUNCT
ecj-11500	37	43	targeted	target	VERB
ecj-11500	37	44	therapy	therapy	NOUN
ecj-11500	37	45	.	.	PUNCT
ecj-11500	38	1	this	this	PRON
ecj-11500	38	2	is	be	AUX
ecj-11500	38	3	particularly	particularly	ADV
ecj-11500	38	4	important	important	ADJ
ecj-11500	38	5	in	in	ADP
ecj-11500	38	6	complex	complex	ADJ
ecj-11500	38	7	clinical	clinical	ADJ
ecj-11500	38	8	scenarios	scenario	NOUN
ecj-11500	38	9	where	where	SCONJ
ecj-11500	38	10	standard	standard	ADJ
ecj-11500	38	11	coagulation	coagulation	NOUN
ecj-11500	38	12	tests	test	NOUN
ecj-11500	38	13	may	may	AUX
ecj-11500	38	14	not	not	PART
ecj-11500	38	15	provide	provide	VERB
ecj-11500	38	16	a	a	DET
ecj-11500	38	17	complete	complete	ADJ
ecj-11500	38	18	picture	picture	NOUN
ecj-11500	38	19	of	of	ADP
ecj-11500	38	20	the	the	DET
ecj-11500	38	21	patient	patient	NOUN
ecj-11500	38	22	’s	’s	PART
ecj-11500	38	23	coagulation	coagulation	NOUN
ecj-11500	38	24	status.4	status.4	PROPN
ecj-11500	38	25	the	the	DET
ecj-11500	38	26	use	use	NOUN
ecj-11500	38	27	of	of	ADP
ecj-11500	38	28	thromboelastometry	thromboelastometry	NOUN
ecj-11500	38	29	in	in	ADP
ecj-11500	38	30	guiding	guide	VERB
ecj-11500	38	31	pcc	pcc	NOUN
ecj-11500	38	32	therapy	therapy	NOUN
ecj-11500	38	33	has	have	VERB
ecj-11500	38	34	the	the	DET
ecj-11500	38	35	potential	potential	NOUN
ecj-11500	38	36	to	to	PART
ecj-11500	38	37	optimize	optimize	VERB
ecj-11500	38	38	patient	patient	ADJ
ecj-11500	38	39	outcomes	outcome	NOUN
ecj-11500	38	40	,	,	PUNCT
ecj-11500	38	41	minimize	minimize	VERB
ecj-11500	38	42	the	the	DET
ecj-11500	38	43	risk	risk	NOUN
ecj-11500	38	44	of	of	ADP
ecj-11500	38	45	adverse	adverse	ADJ
ecj-11500	38	46	events	event	NOUN
ecj-11500	38	47	,	,	PUNCT
ecj-11500	38	48	and	and	CCONJ
ecj-11500	38	49	contribute	contribute	VERB
ecj-11500	38	50	to	to	ADP
ecj-11500	38	51	more	more	ADJ
ecj-11500	38	52	cost	cost	NOUN
ecj-11500	38	53	-	-	PUNCT
ecj-11500	38	54	effective	effective	ADJ
ecj-11500	38	55	care	care	NOUN
ecj-11500	38	56	.	.	PUNCT
ecj-11500	39	1	this	this	DET
ecj-11500	39	2	narrative	narrative	ADJ
ecj-11500	39	3	review	review	NOUN
ecj-11500	39	4	will	will	AUX
ecj-11500	39	5	explore	explore	VERB
ecj-11500	39	6	the	the	DET
ecj-11500	39	7	advantages	advantage	NOUN
ecj-11500	39	8	and	and	CCONJ
ecj-11500	39	9	drawbacks	drawback	NOUN
ecj-11500	39	10	of	of	ADP
ecj-11500	39	11	three	three	NUM
ecj-11500	39	12	-	-	PUNCT
ecj-11500	39	13	factor	factor	NOUN
ecj-11500	39	14	versus	versus	ADP
ecj-11500	39	15	four	four	NUM
ecj-11500	39	16	-	-	PUNCT
ecj-11500	39	17	factor	factor	NOUN
ecj-11500	39	18	pcc	pcc	NOUN
ecj-11500	39	19	,	,	PUNCT
ecj-11500	39	20	and	and	CCONJ
ecj-11500	39	21	discuss	discuss	VERB
ecj-11500	39	22	the	the	DET
ecj-11500	39	23	role	role	NOUN
ecj-11500	39	24	of	of	ADP
ecj-11500	39	25	thromboelastometry	thromboelastometry	NOUN
ecj-11500	39	26	in	in	ADP
ecj-11500	39	27	guiding	guide	VERB
ecj-11500	39	28	their	their	PRON
ecj-11500	39	29	use.5	use.5	ADJ
ecj-11500	39	30	prothrombin	prothrombin	NOUN
ecj-11500	39	31	complex	complex	ADJ
ecj-11500	39	32	concentrate	concentrate	NOUN
ecj-11500	39	33	(	(	PUNCT
ecj-11500	39	34	pcc	pcc	NOUN
ecj-11500	39	35	)	)	PUNCT
ecj-11500	39	36	prothrombin	prothrombin	ADJ
ecj-11500	39	37	complex	complex	ADJ
ecj-11500	39	38	concentrate	concentrate	NOUN
ecj-11500	39	39	(	(	PUNCT
ecj-11500	39	40	pcc	pcc	NOUN
ecj-11500	39	41	)	)	PUNCT
ecj-11500	39	42	is	be	AUX
ecj-11500	39	43	derived	derive	VERB
ecj-11500	39	44	from	from	ADP
ecj-11500	39	45	the	the	DET
ecj-11500	39	46	process	process	NOUN
ecj-11500	39	47	of	of	ADP
ecj-11500	39	48	ion	ion	NOUN
ecj-11500	39	49	-	-	PUNCT
ecj-11500	39	50	exchange	exchange	NOUN
ecj-11500	39	51	chromatography	chromatography	NOUN
ecj-11500	39	52	from	from	ADP
ecj-11500	39	53	the	the	DET
ecj-11500	39	54	cryoprecipitate	cryoprecipitate	NOUN
ecj-11500	39	55	supernatant	supernatant	NOUN
ecj-11500	39	56	of	of	ADP
ecj-11500	39	57	large	large	ADJ
ecj-11500	39	58	plasma	plasma	NOUN
ecj-11500	39	59	pools	pool	NOUN
ecj-11500	39	60	,	,	PUNCT
ecj-11500	39	61	after	after	ADP
ecj-11500	39	62	the	the	DET
ecj-11500	39	63	removal	removal	NOUN
ecj-11500	39	64	of	of	ADP
ecj-11500	39	65	antithrombin	antithrombin	NOUN
ecj-11500	39	66	and	and	CCONJ
ecj-11500	39	67	factor	factor	NOUN
ecj-11500	39	68	xi	xi	PROPN
ecj-11500	39	69	.	.	PUNCT
ecj-11500	40	1	depending	depend	VERB
ecj-11500	40	2	on	on	ADP
ecj-11500	40	3	the	the	DET
ecj-11500	40	4	processing	processing	NOUN
ecj-11500	40	5	techniques	technique	NOUN
ecj-11500	40	6	,	,	PUNCT
ecj-11500	40	7	pcc	pcc	NOUN
ecj-11500	40	8	can	can	AUX
ecj-11500	40	9	be	be	AUX
ecj-11500	40	10	classified	classify	VERB
ecj-11500	40	11	into	into	ADP
ecj-11500	40	12	:	:	PUNCT
ecj-11500	40	13	i	i	NOUN
ecj-11500	40	14	)	)	PUNCT
ecj-11500	40	15	three	three	NUM
ecj-11500	40	16	-	-	PUNCT
ecj-11500	40	17	factor	factor	NOUN
ecj-11500	40	18	pcc	pcc	NOUN
ecj-11500	40	19	(	(	PUNCT
ecj-11500	40	20	contains	contain	VERB
ecj-11500	40	21	factors	factor	NOUN
ecj-11500	40	22	ii	ii	PROPN
ecj-11500	40	23	,	,	PUNCT
ecj-11500	40	24	ix	ix	ADV
ecj-11500	40	25	,	,	PUNCT
ecj-11500	40	26	and	and	CCONJ
ecj-11500	40	27	x	x	X
ecj-11500	40	28	)	)	PUNCT
ecj-11500	40	29	,	,	PUNCT
ecj-11500	40	30	and	and	CCONJ
ecj-11500	40	31	ii	ii	X
ecj-11500	40	32	)	)	PUNCT
ecj-11500	40	33	four	four	NUM
ecj-11500	40	34	-	-	PUNCT
ecj-11500	40	35	factor	factor	NOUN
ecj-11500	40	36	pcc	pcc	NOUN
ecj-11500	40	37	(	(	PUNCT
ecj-11500	40	38	encompasses	encompass	VERB
ecj-11500	40	39	factors	factors	PROPN
ecj-11500	40	40	ii	ii	PROPN
ecj-11500	40	41	,	,	PUNCT
ecj-11500	40	42	vii	vii	PROPN
ecj-11500	40	43	,	,	PUNCT
ecj-11500	40	44	ix	ix	ADV
ecj-11500	40	45	,	,	PUNCT
ecj-11500	40	46	and	and	CCONJ
ecj-11500	40	47	x	x	X
ecj-11500	40	48	)	)	PUNCT
ecj-11500	40	49	.	.	PUNCT
ecj-11500	41	1	three	three	NUM
ecj-11500	41	2	-	-	PUNCT
ecj-11500	41	3	factor	factor	NOUN
ecj-11500	41	4	prothrombin	prothrombin	NOUN
ecj-11500	41	5	complex	complex	ADJ
ecj-11500	41	6	three	three	NUM
ecj-11500	41	7	-	-	PUNCT
ecj-11500	41	8	factor	factor	NOUN
ecj-11500	41	9	prothrombin	prothrombin	NOUN
ecj-11500	41	10	complex	complex	ADJ
ecj-11500	41	11	concentrate	concentrate	NOUN
ecj-11500	41	12	(	(	PUNCT
ecj-11500	41	13	pcc3	pcc3	PROPN
ecj-11500	41	14	)	)	PUNCT
ecj-11500	41	15	is	be	AUX
ecj-11500	41	16	a	a	DET
ecj-11500	41	17	vital	vital	ADJ
ecj-11500	41	18	therapeutic	therapeutic	ADJ
ecj-11500	41	19	agent	agent	NOUN
ecj-11500	41	20	used	use	VERB
ecj-11500	41	21	in	in	ADP
ecj-11500	41	22	the	the	DET
ecj-11500	41	23	management	management	NOUN
ecj-11500	41	24	of	of	ADP
ecj-11500	41	25	bleeding	bleed	VERB
ecj-11500	41	26	disorders	disorder	NOUN
ecj-11500	41	27	,	,	PUNCT
ecj-11500	41	28	particularly	particularly	ADV
ecj-11500	41	29	in	in	ADP
ecj-11500	41	30	the	the	DET
ecj-11500	41	31	context	context	NOUN
ecj-11500	41	32	of	of	ADP
ecj-11500	41	33	spontaneous	spontaneous	ADJ
ecj-11500	41	34	intracerebral	intracerebral	ADJ
ecj-11500	41	35	hemorrhage	hemorrhage	NOUN
ecj-11500	41	36	(	(	PUNCT
ecj-11500	41	37	ich	ich	NOUN
ecj-11500	41	38	)	)	PUNCT
ecj-11500	41	39	and	and	CCONJ
ecj-11500	41	40	severe	severe	ADJ
ecj-11500	41	41	trauma.6	trauma.6	PROPN
ecj-11500	41	42	-	-	PUNCT
ecj-11500	41	43	8	8	NUM
ecj-11500	41	44	ich	ich	NOUN
ecj-11500	41	45	,	,	PUNCT
ecj-11500	41	46	defined	define	VERB
ecj-11500	41	47	as	as	ADP
ecj-11500	41	48	nontraumatic	nontraumatic	ADJ
ecj-11500	41	49	bleeding	bleeding	NOUN
ecj-11500	41	50	into	into	ADP
ecj-11500	41	51	the	the	DET
ecj-11500	41	52	brain	brain	NOUN
ecj-11500	41	53	parenchyma	parenchyma	NOUN
ecj-11500	41	54	,	,	PUNCT
ecj-11500	41	55	is	be	AUX
ecj-11500	41	56	a	a	DET
ecj-11500	41	57	significant	significant	ADJ
ecj-11500	41	58	global	global	ADJ
ecj-11500	41	59	health	health	NOUN
ecj-11500	41	60	issue	issue	NOUN
ecj-11500	41	61	,	,	PUNCT
ecj-11500	41	62	with	with	ADP
ecj-11500	41	63	high	high	ADJ
ecj-11500	41	64	case	case	NOUN
ecj-11500	41	65	fatality	fatality	NOUN
ecj-11500	41	66	and	and	CCONJ
ecj-11500	41	67	a	a	DET
ecj-11500	41	68	large	large	ADJ
ecj-11500	41	69	proportion	proportion	NOUN
ecj-11500	41	70	of	of	ADP
ecj-11500	41	71	survivors	survivor	NOUN
ecj-11500	41	72	experiencing	experience	VERB
ecj-11500	41	73	dependence	dependence	NOUN
ecj-11500	41	74	within	within	ADP
ecj-11500	41	75	six	six	NUM
ecj-11500	41	76	months	month	NOUN
ecj-11500	41	77	post	post	ADJ
ecj-11500	41	78	-	-	ADJ
ecj-11500	41	79	event.6	event.6	ADJ
ecj-11500	41	80	chronic	chronic	ADJ
ecj-11500	41	81	arterial	arterial	NOUN
ecj-11500	41	82	hypertension	hypertension	NOUN
ecj-11500	41	83	,	,	PUNCT
ecj-11500	41	84	cerebral	cerebral	ADJ
ecj-11500	41	85	amyloid	amyloid	NOUN
ecj-11500	41	86	angiopathy	angiopathy	NOUN
ecj-11500	41	87	,	,	PUNCT
ecj-11500	41	88	and	and	CCONJ
ecj-11500	41	89	anticoagulation	anticoagulation	NOUN
ecj-11500	41	90	are	be	AUX
ecj-11500	41	91	commonly	commonly	ADV
ecj-11500	41	92	associated	associate	VERB
ecj-11500	41	93	with	with	ADP
ecj-11500	41	94	ich	ich	PROPN
ecj-11500	41	95	.	.	PUNCT
ecj-11500	42	1	pcc3	pcc3	PROPN
ecj-11500	42	2	,	,	PUNCT
ecj-11500	42	3	which	which	PRON
ecj-11500	42	4	contains	contain	VERB
ecj-11500	42	5	factors	factor	NOUN
ecj-11500	42	6	ii	ii	PROPN
ecj-11500	42	7	,	,	PUNCT
ecj-11500	42	8	ix	ix	ADV
ecj-11500	42	9	,	,	PUNCT
ecj-11500	42	10	and	and	CCONJ
ecj-11500	42	11	x	x	X
ecj-11500	42	12	,	,	PUNCT
ecj-11500	42	13	is	be	AUX
ecj-11500	42	14	often	often	ADV
ecj-11500	42	15	used	use	VERB
ecj-11500	42	16	for	for	ADP
ecj-11500	42	17	the	the	DET
ecj-11500	42	18	rapid	rapid	ADJ
ecj-11500	42	19	reversal	reversal	NOUN
ecj-11500	42	20	of	of	ADP
ecj-11500	42	21	anticoagulation	anticoagulation	NOUN
ecj-11500	42	22	in	in	ADP
ecj-11500	42	23	patients	patient	NOUN
ecj-11500	42	24	with	with	ADP
ecj-11500	42	25	major	major	ADJ
ecj-11500	42	26	bleeding	bleeding	NOUN
ecj-11500	42	27	or	or	CCONJ
ecj-11500	42	28	prior	prior	ADV
ecj-11500	42	29	to	to	ADP
ecj-11500	42	30	emergency	emergency	NOUN
ecj-11500	42	31	surgery	surgery	NOUN
ecj-11500	42	32	.	.	PUNCT
ecj-11500	43	1	the	the	DET
ecj-11500	43	2	choice	choice	NOUN
ecj-11500	43	3	of	of	ADP
ecj-11500	43	4	pcc3	pcc3	NOUN
ecj-11500	43	5	is	be	AUX
ecj-11500	43	6	often	often	ADV
ecj-11500	43	7	influenced	influence	VERB
ecj-11500	43	8	by	by	ADP
ecj-11500	43	9	the	the	DET
ecj-11500	43	10	clinical	clinical	ADJ
ecj-11500	43	11	context	context	NOUN
ecj-11500	43	12	,	,	PUNCT
ecj-11500	43	13	the	the	DET
ecj-11500	43	14	specific	specific	ADJ
ecj-11500	43	15	coagulation	coagulation	NOUN
ecj-11500	43	16	factor	factor	NOUN
ecj-11500	43	17	deficiencies	deficiency	NOUN
ecj-11500	43	18	present	present	ADJ
ecj-11500	43	19	,	,	PUNCT
ecj-11500	43	20	and	and	CCONJ
ecj-11500	43	21	the	the	DET
ecj-11500	43	22	risk	risk	NOUN
ecj-11500	43	23	of	of	ADP
ecj-11500	43	24	potential	potential	ADJ
ecj-11500	43	25	adverse	adverse	ADJ
ecj-11500	43	26	events.7	events.7	NOUN
ecj-11500	43	27	despite	despite	SCONJ
ecj-11500	43	28	the	the	DET
ecj-11500	43	29	effectiveness	effectiveness	NOUN
ecj-11500	43	30	of	of	ADP
ecj-11500	43	31	pcc3	pcc3	NOUN
ecj-11500	43	32	in	in	ADP
ecj-11500	43	33	managing	manage	VERB
ecj-11500	43	34	bleeding	bleed	VERB
ecj-11500	43	35	disorders	disorder	NOUN
ecj-11500	43	36	,	,	PUNCT
ecj-11500	43	37	it	it	PRON
ecj-11500	43	38	is	be	AUX
ecj-11500	43	39	not	not	PART
ecj-11500	43	40	without	without	ADP
ecj-11500	43	41	drawbacks	drawback	NOUN
ecj-11500	43	42	.	.	PUNCT
ecj-11500	44	1	the	the	DET
ecj-11500	44	2	absence	absence	NOUN
ecj-11500	44	3	of	of	ADP
ecj-11500	44	4	factor	factor	NOUN
ecj-11500	44	5	vii	vii	PROPN
ecj-11500	44	6	in	in	ADP
ecj-11500	44	7	pcc3	pcc3	PROPN
ecj-11500	44	8	may	may	AUX
ecj-11500	44	9	limit	limit	VERB
ecj-11500	44	10	its	its	PRON
ecj-11500	44	11	efficacy	efficacy	NOUN
ecj-11500	44	12	in	in	ADP
ecj-11500	44	13	certain	certain	ADJ
ecj-11500	44	14	clinical	clinical	ADJ
ecj-11500	44	15	scenarios	scenario	NOUN
ecj-11500	44	16	,	,	PUNCT
ecj-11500	44	17	particularly	particularly	ADV
ecj-11500	44	18	in	in	ADP
ecj-11500	44	19	patients	patient	NOUN
ecj-11500	44	20	with	with	ADP
ecj-11500	44	21	deficiencies	deficiency	NOUN
ecj-11500	44	22	or	or	CCONJ
ecj-11500	44	23	functional	functional	ADJ
ecj-11500	44	24	impairments	impairment	NOUN
ecj-11500	44	25	of	of	ADP
ecj-11500	44	26	this	this	DET
ecj-11500	44	27	factor.7	factor.7	NOUN
ecj-11500	44	28	furthermore	furthermore	ADV
ecj-11500	44	29	,	,	PUNCT
ecj-11500	44	30	the	the	DET
ecj-11500	44	31	risk	risk	NOUN
ecj-11500	44	32	of	of	ADP
ecj-11500	44	33	thromboembolic	thromboembolic	ADJ
ecj-11500	44	34	events	event	NOUN
ecj-11500	44	35	remains	remain	VERB
ecj-11500	44	36	a	a	DET
ecj-11500	44	37	significant	significant	ADJ
ecj-11500	44	38	concern	concern	NOUN
ecj-11500	44	39	,	,	PUNCT
ecj-11500	44	40	necessitating	necessitate	VERB
ecj-11500	44	41	careful	careful	ADJ
ecj-11500	44	42	consideration	consideration	NOUN
ecj-11500	44	43	and	and	CCONJ
ecj-11500	44	44	monitoring.8	monitoring.8	NOUN
ecj-11500	44	45	the	the	DET
ecj-11500	44	46	management	management	NOUN
ecj-11500	44	47	of	of	ADP
ecj-11500	44	48	bleeding	bleeding	NOUN
ecj-11500	44	49	and	and	CCONJ
ecj-11500	44	50	coagulopathy	coagulopathy	ADJ
ecj-11500	44	51	following	follow	VERB
ecj-11500	44	52	major	major	ADJ
ecj-11500	44	53	trauma	trauma	NOUN
ecj-11500	44	54	requires	require	VERB
ecj-11500	44	55	a	a	DET
ecj-11500	44	56	comprehensive	comprehensive	ADJ
ecj-11500	44	57	,	,	PUNCT
ecj-11500	44	58	multidisciplinary	multidisciplinary	ADJ
ecj-11500	44	59	approach	approach	NOUN
ecj-11500	44	60	.	.	PUNCT
ecj-11500	45	1	the	the	DET
ecj-11500	45	2	use	use	NOUN
ecj-11500	45	3	of	of	ADP
ecj-11500	45	4	pcc3	pcc3	NOUN
ecj-11500	45	5	should	should	AUX
ecj-11500	45	6	be	be	AUX
ecj-11500	45	7	guided	guide	VERB
ecj-11500	45	8	by	by	ADP
ecj-11500	45	9	evidence	evidence	NOUN
ecj-11500	45	10	-	-	PUNCT
ecj-11500	45	11	based	base	VERB
ecj-11500	45	12	clinical	clinical	ADJ
ecj-11500	45	13	protocols	protocol	NOUN
ecj-11500	45	14	to	to	PART
ecj-11500	45	15	ensure	ensure	VERB
ecj-11500	45	16	a	a	DET
ecj-11500	45	17	uniform	uniform	ADJ
ecj-11500	45	18	and	and	CCONJ
ecj-11500	45	19	high	high	ADJ
ecj-11500	45	20	standard	standard	NOUN
ecj-11500	45	21	of	of	ADP
ecj-11500	45	22	care.8	care.8	NOUN
ecj-11500	45	23	four	four	NUM
ecj-11500	45	24	-	-	PUNCT
ecj-11500	45	25	factor	factor	NOUN
ecj-11500	45	26	prothrombin	prothrombin	NOUN
ecj-11500	45	27	complex	complex	ADJ
ecj-11500	45	28	four	four	NUM
ecj-11500	45	29	-	-	PUNCT
ecj-11500	45	30	factor	factor	NOUN
ecj-11500	45	31	prothrombin	prothrombin	NOUN
ecj-11500	45	32	complex	complex	ADJ
ecj-11500	45	33	concentrate	concentrate	NOUN
ecj-11500	45	34	(	(	PUNCT
ecj-11500	45	35	pcc4	pcc4	PROPN
ecj-11500	45	36	)	)	PUNCT
ecj-11500	45	37	is	be	AUX
ecj-11500	45	38	an	an	DET
ecj-11500	45	39	essential	essential	ADJ
ecj-11500	45	40	therapeutic	therapeutic	ADJ
ecj-11500	45	41	agent	agent	NOUN
ecj-11500	45	42	used	use	VERB
ecj-11500	45	43	in	in	ADP
ecj-11500	45	44	the	the	DET
ecj-11500	45	45	management	management	NOUN
ecj-11500	45	46	of	of	ADP
ecj-11500	45	47	bleeding	bleed	VERB
ecj-11500	45	48	disorders	disorder	NOUN
ecj-11500	45	49	,	,	PUNCT
ecj-11500	45	50	particularly	particularly	ADV
ecj-11500	45	51	in	in	ADP
ecj-11500	45	52	the	the	DET
ecj-11500	45	53	context	context	NOUN
ecj-11500	45	54	of	of	ADP
ecj-11500	45	55	anticoagulant	anticoagulant	NOUN
ecj-11500	45	56	-	-	PUNCT
ecj-11500	45	57	associated	associate	VERB
ecj-11500	45	58	major	major	ADJ
ecj-11500	45	59	or	or	CCONJ
ecj-11500	45	60	life	life	NOUN
ecj-11500	45	61	-	-	PUNCT
ecj-11500	45	62	threatening	threaten	VERB
ecj-11500	45	63	bleeding.9	bleeding.9	PROPN
ecj-11500	45	64	pcc4	pcc4	NOUN
ecj-11500	45	65	contains	contain	VERB
ecj-11500	45	66	factors	factors	PROPN
ecj-11500	45	67	ii	ii	PROPN
ecj-11500	45	68	,	,	PUNCT
ecj-11500	45	69	vii	vii	PROPN
ecj-11500	45	70	,	,	PUNCT
ecj-11500	45	71	ix	ix	ADV
ecj-11500	45	72	,	,	PUNCT
ecj-11500	45	73	and	and	CCONJ
ecj-11500	45	74	x	x	X
ecj-11500	45	75	,	,	PUNCT
ecj-11500	45	76	and	and	CCONJ
ecj-11500	45	77	is	be	AUX
ecj-11500	45	78	often	often	ADV
ecj-11500	45	79	used	use	VERB
ecj-11500	45	80	for	for	ADP
ecj-11500	45	81	the	the	DET
ecj-11500	45	82	rapid	rapid	ADJ
ecj-11500	45	83	reversal	reversal	NOUN
ecj-11500	45	84	of	of	ADP
ecj-11500	45	85	anticoagulation	anticoagulation	NOUN
ecj-11500	45	86	in	in	ADP
ecj-11500	45	87	patients	patient	NOUN
ecj-11500	45	88	with	with	ADP
ecj-11500	45	89	major	major	ADJ
ecj-11500	45	90	bleeding	bleeding	NOUN
ecj-11500	45	91	or	or	CCONJ
ecj-11500	45	92	prior	prior	ADV
ecj-11500	45	93	to	to	ADP
ecj-11500	45	94	emergency	emergency	NOUN
ecj-11500	45	95	surgery.10	surgery.10	NOUN
ecj-11500	45	96	the	the	DET
ecj-11500	45	97	use	use	NOUN
ecj-11500	45	98	of	of	ADP
ecj-11500	45	99	pcc4	pcc4	PROPN
ecj-11500	45	100	has	have	AUX
ecj-11500	45	101	been	be	AUX
ecj-11500	45	102	shown	show	VERB
ecj-11500	45	103	to	to	PART
ecj-11500	45	104	be	be	AUX
ecj-11500	45	105	effective	effective	ADJ
ecj-11500	45	106	in	in	ADP
ecj-11500	45	107	reversing	reverse	VERB
ecj-11500	45	108	the	the	DET
ecj-11500	45	109	effects	effect	NOUN
ecj-11500	45	110	of	of	ADP
ecj-11500	45	111	both	both	CCONJ
ecj-11500	45	112	vitamin	vitamin	NOUN
ecj-11500	45	113	k	k	PROPN
ecj-11500	45	114	antagonists	antagonist	NOUN
ecj-11500	45	115	(	(	PUNCT
ecj-11500	45	116	vkas	vkas	PROPN
ecj-11500	45	117	)	)	PUNCT
ecj-11500	45	118	and	and	CCONJ
ecj-11500	45	119	direct	direct	ADJ
ecj-11500	45	120	oral	oral	ADJ
ecj-11500	45	121	anticoagulants	anticoagulant	NOUN
ecj-11500	45	122	(	(	PUNCT
ecj-11500	45	123	doacs	doac	NOUN
ecj-11500	45	124	)	)	PUNCT
ecj-11500	45	125	.	.	PUNCT
ecj-11500	46	1	this	this	PRON
ecj-11500	46	2	is	be	AUX
ecj-11500	46	3	particularly	particularly	ADV
ecj-11500	46	4	important	important	ADJ
ecj-11500	46	5	given	give	VERB
ecj-11500	46	6	the	the	DET
ecj-11500	46	7	increasing	increase	VERB
ecj-11500	46	8	use	use	NOUN
ecj-11500	46	9	of	of	ADP
ecj-11500	46	10	these	these	DET
ecj-11500	46	11	agents	agent	NOUN
ecj-11500	46	12	in	in	ADP
ecj-11500	46	13	clinical	clinical	ADJ
ecj-11500	46	14	practice	practice	NOUN
ecj-11500	46	15	and	and	CCONJ
ecj-11500	46	16	the	the	DET
ecj-11500	46	17	associated	associated	ADJ
ecj-11500	46	18	risk	risk	NOUN
ecj-11500	46	19	of	of	ADP
ecj-11500	46	20	major	major	ADJ
ecj-11500	46	21	and	and	CCONJ
ecj-11500	46	22	life	life	NOUN
ecj-11500	46	23	-	-	PUNCT
ecj-11500	46	24	threatening	threaten	VERB
ecj-11500	46	25	bleeding.9	bleeding.9	NOUN
ecj-11500	46	26	however	however	ADV
ecj-11500	46	27	,	,	PUNCT
ecj-11500	46	28	the	the	DET
ecj-11500	46	29	use	use	NOUN
ecj-11500	46	30	of	of	ADP
ecj-11500	46	31	pcc4	pcc4	PROPN
ecj-11500	46	32	is	be	AUX
ecj-11500	46	33	not	not	PART
ecj-11500	46	34	without	without	ADP
ecj-11500	46	35	challenges	challenge	NOUN
ecj-11500	46	36	.	.	PUNCT
ecj-11500	47	1	the	the	DET
ecj-11500	47	2	risk	risk	NOUN
ecj-11500	47	3	of	of	ADP
ecj-11500	47	4	thromboembolic	thromboembolic	ADJ
ecj-11500	47	5	events	event	NOUN
ecj-11500	47	6	remains	remain	VERB
ecj-11500	47	7	a	a	DET
ecj-11500	47	8	significant	significant	ADJ
ecj-11500	47	9	concern	concern	NOUN
ecj-11500	47	10	,	,	PUNCT
ecj-11500	47	11	necessitating	necessitate	VERB
ecj-11500	47	12	careful	careful	ADJ
ecj-11500	47	13	consideration	consideration	NOUN
ecj-11500	47	14	and	and	CCONJ
ecj-11500	47	15	monitoring.10	monitoring.10	NOUN
ecj-11500	47	16	furthermore	furthermore	ADV
ecj-11500	47	17	,	,	PUNCT
ecj-11500	47	18	the	the	DET
ecj-11500	47	19	lack	lack	NOUN
ecj-11500	47	20	of	of	ADP
ecj-11500	47	21	specific	specific	ADJ
ecj-11500	47	22	reversal	reversal	NOUN
ecj-11500	47	23	antidotes	antidote	NOUN
ecj-11500	47	24	for	for	ADP
ecj-11500	47	25	doacs	doac	NOUN
ecj-11500	47	26	poses	pose	VERB
ecj-11500	47	27	a	a	DET
ecj-11500	47	28	real	real	ADJ
ecj-11500	47	29	challenge	challenge	NOUN
ecj-11500	47	30	,	,	PUNCT
ecj-11500	47	31	despite	despite	SCONJ
ecj-11500	47	32	accumulating	accumulate	VERB
ecj-11500	47	33	experience	experience	NOUN
ecj-11500	47	34	and	and	CCONJ
ecj-11500	47	35	awareness.9	awareness.9	VERB
ecj-11500	47	36	the	the	DET
ecj-11500	47	37	management	management	NOUN
ecj-11500	47	38	of	of	ADP
ecj-11500	47	39	bleeding	bleeding	NOUN
ecj-11500	47	40	and	and	CCONJ
ecj-11500	47	41	coagulopathy	coagulopathy	ADJ
ecj-11500	47	42	following	follow	VERB
ecj-11500	47	43	major	major	ADJ
ecj-11500	47	44	trauma	trauma	NOUN
ecj-11500	47	45	requires	require	VERB
ecj-11500	47	46	a	a	DET
ecj-11500	47	47	comprehensive	comprehensive	ADJ
ecj-11500	47	48	,	,	PUNCT
ecj-11500	47	49	multidisciplinary	multidisciplinary	ADJ
ecj-11500	47	50	approach	approach	NOUN
ecj-11500	47	51	.	.	PUNCT
ecj-11500	48	1	the	the	DET
ecj-11500	48	2	use	use	NOUN
ecj-11500	48	3	of	of	ADP
ecj-11500	48	4	pcc4	pcc4	PROPN
ecj-11500	48	5	should	should	AUX
ecj-11500	48	6	be	be	AUX
ecj-11500	48	7	guided	guide	VERB
ecj-11500	48	8	by	by	ADP
ecj-11500	48	9	evidence	evidence	NOUN
ecj-11500	48	10	-	-	PUNCT
ecj-11500	48	11	based	base	VERB
ecj-11500	48	12	clinical	clinical	ADJ
ecj-11500	48	13	protocols	protocol	NOUN
ecj-11500	48	14	to	to	PART
ecj-11500	48	15	ensure	ensure	VERB
ecj-11500	48	16	a	a	DET
ecj-11500	48	17	uniform	uniform	ADJ
ecj-11500	48	18	and	and	CCONJ
ecj-11500	48	19	high	high	ADJ
ecj-11500	48	20	standard	standard	NOUN
ecj-11500	48	21	of	of	ADP
ecj-11500	48	22	care.7	care.7	NOUN
ecj-11500	48	23	indications	indication	NOUN
ecj-11500	48	24	initially	initially	ADV
ecj-11500	48	25	developed	develop	VERB
ecj-11500	48	26	for	for	ADP
ecj-11500	48	27	managing	manage	VERB
ecj-11500	48	28	hemophilia	hemophilia	NOUN
ecj-11500	48	29	,	,	PUNCT
ecj-11500	48	30	the	the	DET
ecj-11500	48	31	role	role	NOUN
ecj-11500	48	32	of	of	ADP
ecj-11500	48	33	pcc	pcc	NOUN
ecj-11500	48	34	has	have	AUX
ecj-11500	48	35	significantly	significantly	ADV
ecj-11500	48	36	evolved	evolve	VERB
ecj-11500	48	37	with	with	ADP
ecj-11500	48	38	the	the	DET
ecj-11500	48	39	availability	availability	NOUN
ecj-11500	48	40	of	of	ADP
ecj-11500	48	41	recombinant	recombinant	ADJ
ecj-11500	48	42	replacement	replacement	NOUN
ecj-11500	48	43	factors	factor	NOUN
ecj-11500	48	44	.	.	PUNCT
ecj-11500	49	1	today	today	NOUN
ecj-11500	49	2	,	,	PUNCT
ecj-11500	49	3	it	it	PRON
ecj-11500	49	4	serves	serve	VERB
ecj-11500	49	5	as	as	ADP
ecj-11500	49	6	a	a	DET
ecj-11500	49	7	critical	critical	ADJ
ecj-11500	49	8	replacement	replacement	NOUN
ecj-11500	49	9	therapy	therapy	NOUN
ecj-11500	49	10	for	for	ADP
ecj-11500	49	11	both	both	CCONJ
ecj-11500	49	12	congenital	congenital	ADJ
ecj-11500	49	13	and	and	CCONJ
ecj-11500	49	14	acquired	acquire	VERB
ecj-11500	49	15	vitamin	vitamin	NOUN
ecj-11500	49	16	-	-	PUNCT
ecj-11500	49	17	k	k	NOUN
ecj-11500	49	18	deficiency	deficiency	NOUN
ecj-11500	49	19	,	,	PUNCT
ecj-11500	49	20	especially	especially	ADV
ecj-11500	49	21	in	in	ADP
ecj-11500	49	22	emergent	emergent	ADJ
ecj-11500	49	23	scenarios	scenario	NOUN
ecj-11500	49	24	involving	involve	VERB
ecj-11500	49	25	warfarin	warfarin	NOUN
ecj-11500	49	26	-	-	PUNCT
ecj-11500	49	27	induced	induce	VERB
ecj-11500	49	28	anticoagulant	anticoagulant	ADJ
ecj-11500	49	29	effects	effect	NOUN
ecj-11500	49	30	.	.	PUNCT
ecj-11500	50	1	the	the	DET
ecj-11500	50	2	fda	fda	PROPN
ecj-11500	50	3	-	-	PUNCT
ecj-11500	50	4	approved	approve	VERB
ecj-11500	50	5	indication	indication	NOUN
ecj-11500	50	6	for	for	ADP
ecj-11500	50	7	pcc	pcc	NOUN
ecj-11500	50	8	is	be	AUX
ecj-11500	50	9	the	the	DET
ecj-11500	50	10	urgent	urgent	ADJ
ecj-11500	50	11	reversal	reversal	NOUN
ecj-11500	50	12	of	of	ADP
ecj-11500	50	13	acquired	acquire	VERB
ecj-11500	50	14	coagulation	coagulation	NOUN
ecj-11500	50	15	factor	factor	NOUN
ecj-11500	50	16	deficiency	deficiency	NOUN
ecj-11500	50	17	due	due	ADP
ecj-11500	50	18	to	to	ADP
ecj-11500	50	19	warfarin	warfarin	NOUN
ecj-11500	50	20	-	-	PUNCT
ecj-11500	50	21	induced	induce	VERB
ecj-11500	50	22	anticoagulation	anticoagulation	NOUN
ecj-11500	50	23	.	.	PUNCT
ecj-11500	51	1	this	this	PRON
ecj-11500	51	2	is	be	AUX
ecj-11500	51	3	particularly	particularly	ADV
ecj-11500	51	4	vital	vital	ADJ
ecj-11500	51	5	for	for	ADP
ecj-11500	51	6	patients	patient	NOUN
ecj-11500	51	7	with	with	ADP
ecj-11500	51	8	major	major	ADJ
ecj-11500	51	9	acute	acute	ADJ
ecj-11500	51	10	bleeding	bleeding	NOUN
ecj-11500	51	11	events	event	NOUN
ecj-11500	51	12	or	or	CCONJ
ecj-11500	51	13	those	those	PRON
ecj-11500	51	14	in	in	ADP
ecj-11500	51	15	need	need	NOUN
ecj-11500	51	16	of	of	ADP
ecj-11500	51	17	urgent	urgent	ADJ
ecj-11500	51	18	surgeries	surgery	NOUN
ecj-11500	51	19	.	.	PUNCT
ecj-11500	52	1	the	the	DET
ecj-11500	52	2	american	american	PROPN
ecj-11500	52	3	college	college	PROPN
ecj-11500	52	4	of	of	ADP
ecj-11500	52	5	cardiology	cardiology	NOUN
ecj-11500	52	6	(	(	PUNCT
ecj-11500	52	7	acc	acc	PROPN
ecj-11500	52	8	)	)	PUNCT
ecj-11500	52	9	now	now	ADV
ecj-11500	52	10	recommends	recommend	VERB
ecj-11500	52	11	4	4	NUM
ecj-11500	52	12	-	-	PUNCT
ecj-11500	52	13	factor	factor	NOUN
ecj-11500	52	14	pcc	pcc	NOUN
ecj-11500	52	15	as	as	ADP
ecj-11500	52	16	the	the	DET
ecj-11500	52	17	preferred	preferred	ADJ
ecj-11500	52	18	choice	choice	NOUN
ecj-11500	52	19	for	for	ADP
ecj-11500	52	20	reversing	reverse	VERB
ecj-11500	52	21	warfarin	warfarin	NOUN
ecj-11500	52	22	-	-	PUNCT
ecj-11500	52	23	induced	induce	VERB
ecj-11500	52	24	bleeding.11	bleeding.11	NOUN
ecj-11500	52	25	off	off	ADP
ecj-11500	52	26	-	-	PUNCT
ecj-11500	52	27	label	label	NOUN
ecj-11500	52	28	applications	application	NOUN
ecj-11500	52	29	of	of	ADP
ecj-11500	52	30	pcc	pcc	NOUN
ecj-11500	52	31	include	include	VERB
ecj-11500	52	32	:	:	PUNCT
ecj-11500	52	33	doac	doac	ADJ
ecj-11500	52	34	reversal	reversal	NOUN
ecj-11500	52	35	:	:	PUNCT
ecj-11500	52	36	doacs	doac	NOUN
ecj-11500	52	37	,	,	PUNCT
ecj-11500	52	38	including	include	VERB
ecj-11500	52	39	dabigatran	dabigatran	ADV
ecj-11500	52	40	(	(	PUNCT
ecj-11500	52	41	a	a	DET
ecj-11500	52	42	direct	direct	ADJ
ecj-11500	52	43	thrombin	thrombin	NOUN
ecj-11500	52	44	inhibitor	inhibitor	NOUN
ecj-11500	52	45	)	)	PUNCT
ecj-11500	52	46	and	and	CCONJ
ecj-11500	52	47	factor	factor	NOUN
ecj-11500	52	48	xa	xa	PROPN
ecj-11500	52	49	inhibitors	inhibitor	NOUN
ecj-11500	52	50	such	such	ADJ
ecj-11500	52	51	as	as	ADP
ecj-11500	52	52	rivaroxaban	rivaroxaban	NOUN
ecj-11500	52	53	,	,	PUNCT
ecj-11500	52	54	apixaban	apixaban	ADJ
ecj-11500	52	55	,	,	PUNCT
ecj-11500	52	56	and	and	CCONJ
ecj-11500	52	57	edoxaban	edoxaban	PROPN
ecj-11500	52	58	,	,	PUNCT
ecj-11500	52	59	have	have	AUX
ecj-11500	52	60	revolutionized	revolutionize	VERB
ecj-11500	52	61	anticoagulant	anticoagulant	NOUN
ecj-11500	52	62	therapy	therapy	NOUN
ecj-11500	52	63	.	.	PUNCT
ecj-11500	53	1	their	their	PRON
ecj-11500	53	2	predictable	predictable	ADJ
ecj-11500	53	3	pharmacokinetics	pharmacokinetic	NOUN
ecj-11500	53	4	,	,	PUNCT
ecj-11500	53	5	fewer	few	ADJ
ecj-11500	53	6	drug	drug	NOUN
ecj-11500	53	7	interactions	interaction	NOUN
ecj-11500	53	8	,	,	PUNCT
ecj-11500	53	9	and	and	CCONJ
ecj-11500	53	10	the	the	DET
ecj-11500	53	11	elimination	elimination	NOUN
ecj-11500	53	12	of	of	ADP
ecj-11500	53	13	the	the	DET
ecj-11500	53	14	need	need	NOUN
ecj-11500	53	15	for	for	ADP
ecj-11500	53	16	regular	regular	ADJ
ecj-11500	53	17	monitoring	monitoring	NOUN
ecj-11500	53	18	have	have	AUX
ecj-11500	53	19	made	make	VERB
ecj-11500	53	20	them	they	PRON
ecj-11500	53	21	a	a	DET
ecj-11500	53	22	preferred	preferred	ADJ
ecj-11500	53	23	choice	choice	NOUN
ecj-11500	53	24	in	in	ADP
ecj-11500	53	25	many	many	ADJ
ecj-11500	53	26	clinical	clinical	ADJ
ecj-11500	53	27	scenarios	scenario	NOUN
ecj-11500	53	28	.	.	PUNCT
ecj-11500	54	1	however	however	ADV
ecj-11500	54	2	,	,	PUNCT
ecj-11500	54	3	their	their	PRON
ecj-11500	54	4	widespread	widespread	ADJ
ecj-11500	54	5	use	use	NOUN
ecj-11500	54	6	presents	present	NOUN
ecj-11500	54	7	challenges	challenge	NOUN
ecj-11500	54	8	in	in	ADP
ecj-11500	54	9	situations	situation	NOUN
ecj-11500	54	10	of	of	ADP
ecj-11500	54	11	bleeding	bleeding	NOUN
ecj-11500	54	12	or	or	CCONJ
ecj-11500	54	13	urgent	urgent	ADJ
ecj-11500	54	14	surgery	surgery	NOUN
ecj-11500	54	15	.	.	PUNCT
ecj-11500	55	1	for	for	ADP
ecj-11500	55	2	the	the	DET
ecj-11500	55	3	reversal	reversal	NOUN
ecj-11500	55	4	of	of	ADP
ecj-11500	55	5	dabigatran	dabigatran	NOUN
ecj-11500	55	6	,	,	PUNCT
ecj-11500	55	7	idarucizumab	idarucizumab	NOUN
ecj-11500	55	8	,	,	PUNCT
ecj-11500	55	9	a	a	DET
ecj-11500	55	10	monoclonal	monoclonal	NOUN
ecj-11500	55	11	antibody	antibody	NOUN
ecj-11500	55	12	fragment	fragment	NOUN
ecj-11500	55	13	,	,	PUNCT
ecj-11500	55	14	has	have	AUX
ecj-11500	55	15	been	be	AUX
ecj-11500	55	16	approved	approve	VERB
ecj-11500	55	17	and	and	CCONJ
ecj-11500	55	18	demonstrated	demonstrate	VERB
ecj-11500	55	19	effectiveness	effectiveness	NOUN
ecj-11500	55	20	.	.	PUNCT
ecj-11500	56	1	factor	factor	NOUN
ecj-11500	56	2	xa	xa	PROPN
ecj-11500	56	3	inhibitors	inhibitor	NOUN
ecj-11500	56	4	,	,	PUNCT
ecj-11500	56	5	on	on	ADP
ecj-11500	56	6	the	the	DET
ecj-11500	56	7	other	other	ADJ
ecj-11500	56	8	hand	hand	NOUN
ecj-11500	56	9	,	,	PUNCT
ecj-11500	56	10	can	can	AUX
ecj-11500	56	11	be	be	AUX
ecj-11500	56	12	counteracted	counteract	VERB
ecj-11500	56	13	using	use	VERB
ecj-11500	56	14	andexanet	andexanet	PROPN
ecj-11500	56	15	alfa	alfa	PROPN
ecj-11500	56	16	,	,	PUNCT
ecj-11500	56	17	a	a	DET
ecj-11500	56	18	modified	modify	VERB
ecj-11500	56	19	recombinant	recombinant	ADJ
ecj-11500	56	20	human	human	ADJ
ecj-11500	56	21	factor	factor	NOUN
ecj-11500	56	22	xa	xa	PROPN
ecj-11500	56	23	protein	protein	NOUN
ecj-11500	56	24	.	.	PUNCT
ecj-11500	57	1	in	in	ADP
ecj-11500	57	2	the	the	DET
ecj-11500	57	3	absence	absence	NOUN
ecj-11500	57	4	of	of	ADP
ecj-11500	57	5	these	these	DET
ecj-11500	57	6	specific	specific	ADJ
ecj-11500	57	7	antidotes	antidote	NOUN
ecj-11500	57	8	or	or	CCONJ
ecj-11500	57	9	when	when	SCONJ
ecj-11500	57	10	they	they	PRON
ecj-11500	57	11	are	be	AUX
ecj-11500	57	12	not	not	PART
ecj-11500	57	13	readily	readily	ADV
ecj-11500	57	14	available	available	ADJ
ecj-11500	57	15	,	,	PUNCT
ecj-11500	57	16	pccs	pccs	PROPN
ecj-11500	57	17	have	have	AUX
ecj-11500	57	18	been	be	AUX
ecj-11500	57	19	proposed	propose	VERB
ecj-11500	57	20	as	as	ADP
ecj-11500	57	21	a	a	DET
ecj-11500	57	22	potential	potential	ADJ
ecj-11500	57	23	alternative	alternative	NOUN
ecj-11500	57	24	.	.	PUNCT
ecj-11500	58	1	the	the	DET
ecj-11500	58	2	american	american	PROPN
ecj-11500	58	3	college	college	PROPN
ecj-11500	58	4	of	of	ADP
ecj-11500	58	5	cardiology	cardiology	NOUN
ecj-11500	58	6	(	(	PUNCT
ecj-11500	58	7	acc	acc	PROPN
ecj-11500	58	8	)	)	PUNCT
ecj-11500	58	9	endorses	endorse	VERB
ecj-11500	58	10	pcc	pcc	NOUN
ecj-11500	58	11	for	for	ADP
ecj-11500	58	12	reversing	reverse	VERB
ecj-11500	58	13	xa	xa	PROPN
ecj-11500	58	14	inhibitors	inhibitor	NOUN
ecj-11500	58	15	and	and	CCONJ
ecj-11500	58	16	direct	direct	VERB
ecj-11500	58	17	thrombin	thrombin	NOUN
ecj-11500	58	18	inhibitors	inhibitor	NOUN
ecj-11500	58	19	when	when	SCONJ
ecj-11500	58	20	specific	specific	ADJ
ecj-11500	58	21	antidotes	antidote	NOUN
ecj-11500	58	22	are	be	AUX
ecj-11500	58	23	not	not	PART
ecj-11500	58	24	accessible	accessible	ADJ
ecj-11500	58	25	.	.	PUNCT
ecj-11500	59	1	while	while	SCONJ
ecj-11500	59	2	pccs	pccs	PROPN
ecj-11500	59	3	are	be	AUX
ecj-11500	59	4	tradi	tradi	NOUN
ecj-11500	59	5	mini	mini	ADJ
ecj-11500	59	6	review	review	NOUN
ecj-11500	59	7	[	[	X
ecj-11500	59	8	emergency	emergency	NOUN
ecj-11500	59	9	care	care	NOUN
ecj-11500	59	10	journal	journal	NOUN
ecj-11500	59	11	2023	2023	NUM
ecj-11500	59	12	;	;	PUNCT
ecj-11500	59	13	19:11500	19:11500	NUM
ecj-11500	59	14	]	]	X
ecj-11500	60	1	[	[	X
ecj-11500	60	2	page	page	NOUN
ecj-11500	60	3	6	6	NUM
ecj-11500	60	4	]	]	X
ecj-11500	60	5	non	non	ADJ
ecj-11500	60	6	-co	-co	PROPN
ecj-11500	60	7	mmerc	mmerc	PROPN
ecj-11500	60	8	ial	ial	PROPN
ecj-11500	60	9	us	us	PROPN
ecj-11500	60	10	e	e	NOUN
ecj-11500	60	11	o	o	NOUN
ecj-11500	60	12	nly	nly	ADV
ecj-11500	60	13	tionally	tionally	ADV
ecj-11500	60	14	indicated	indicate	VERB
ecj-11500	60	15	for	for	ADP
ecj-11500	60	16	vitamin	vitamin	NOUN
ecj-11500	60	17	k	k	PROPN
ecj-11500	60	18	antagonist	antagonist	NOUN
ecj-11500	60	19	reversal	reversal	NOUN
ecj-11500	60	20	,	,	PUNCT
ecj-11500	60	21	emerging	emerge	VERB
ecj-11500	60	22	evidence	evidence	NOUN
ecj-11500	60	23	highlights	highlight	VERB
ecj-11500	60	24	their	their	PRON
ecj-11500	60	25	potential	potential	NOUN
ecj-11500	60	26	in	in	ADP
ecj-11500	60	27	counteracting	counteract	VERB
ecj-11500	60	28	doac	doac	ADJ
ecj-11500	60	29	effects	effect	NOUN
ecj-11500	60	30	.	.	PUNCT
ecj-11500	61	1	despite	despite	SCONJ
ecj-11500	61	2	this	this	PRON
ecj-11500	61	3	,	,	PUNCT
ecj-11500	61	4	clinicians	clinician	NOUN
ecj-11500	61	5	should	should	AUX
ecj-11500	61	6	approach	approach	VERB
ecj-11500	61	7	the	the	DET
ecj-11500	61	8	use	use	NOUN
ecj-11500	61	9	of	of	ADP
ecj-11500	61	10	pccs	pccs	NOUN
ecj-11500	61	11	in	in	ADP
ecj-11500	61	12	doac	doac	ADJ
ecj-11500	61	13	reversal	reversal	NOUN
ecj-11500	61	14	with	with	ADP
ecj-11500	61	15	caution	caution	NOUN
ecj-11500	61	16	,	,	PUNCT
ecj-11500	61	17	basing	base	VERB
ecj-11500	61	18	decisions	decision	NOUN
ecj-11500	61	19	on	on	ADP
ecj-11500	61	20	available	available	ADJ
ecj-11500	61	21	guidelines	guideline	NOUN
ecj-11500	61	22	,	,	PUNCT
ecj-11500	61	23	current	current	ADJ
ecj-11500	61	24	evidence	evidence	NOUN
ecj-11500	61	25	,	,	PUNCT
ecj-11500	61	26	and	and	CCONJ
ecj-11500	61	27	clinical	clinical	ADJ
ecj-11500	61	28	judgment.12	judgment.12	NOUN
ecj-11500	61	29	treatment	treatment	NOUN
ecj-11500	61	30	for	for	ADP
ecj-11500	61	31	congenital	congenital	ADJ
ecj-11500	61	32	deficiency	deficiency	NOUN
ecj-11500	61	33	:	:	PUNCT
ecj-11500	61	34	in	in	ADP
ecj-11500	61	35	rare	rare	ADJ
ecj-11500	61	36	instances	instance	NOUN
ecj-11500	61	37	where	where	SCONJ
ecj-11500	61	38	purified	purified	ADJ
ecj-11500	61	39	factor	factor	NOUN
ecj-11500	61	40	is	be	AUX
ecj-11500	61	41	n’t	not	PART
ecj-11500	61	42	available	available	ADJ
ecj-11500	61	43	,	,	PUNCT
ecj-11500	61	44	4	4	NUM
ecj-11500	61	45	-	-	PUNCT
ecj-11500	61	46	factor	factor	NOUN
ecj-11500	61	47	pcc	pcc	NOUN
ecj-11500	61	48	can	can	AUX
ecj-11500	61	49	be	be	AUX
ecj-11500	61	50	utilized	utilize	VERB
ecj-11500	61	51	as	as	ADP
ecj-11500	61	52	a	a	DET
ecj-11500	61	53	treatment	treatment	NOUN
ecj-11500	61	54	or	or	CCONJ
ecj-11500	61	55	prophylaxis	prophylaxis	NOUN
ecj-11500	61	56	of	of	ADP
ecj-11500	61	57	bleeding	bleed	VERB
ecj-11500	61	58	in	in	ADP
ecj-11500	61	59	patients	patient	NOUN
ecj-11500	61	60	with	with	ADP
ecj-11500	61	61	a	a	DET
ecj-11500	61	62	congenital	congenital	ADJ
ecj-11500	61	63	deficiency	deficiency	NOUN
ecj-11500	61	64	of	of	ADP
ecj-11500	61	65	vitamin	vitamin	NOUN
ecj-11500	61	66	k	k	ADJ
ecj-11500	61	67	-	-	ADJ
ecj-11500	61	68	dependent	dependent	ADJ
ecj-11500	61	69	coagulation	coagulation	NOUN
ecj-11500	61	70	factors	factor	NOUN
ecj-11500	61	71	.	.	PUNCT
ecj-11500	62	1	peri	peri	NOUN
ecj-11500	62	2	-	-	PUNCT
ecj-11500	62	3	operative	operative	ADJ
ecj-11500	62	4	use	use	NOUN
ecj-11500	63	1	:	:	PUNCT
ecj-11500	63	2	pcc	pcc	NOUN
ecj-11500	63	3	has	have	AUX
ecj-11500	63	4	shown	show	VERB
ecj-11500	63	5	efficacy	efficacy	NOUN
ecj-11500	63	6	in	in	ADP
ecj-11500	63	7	reducing	reduce	VERB
ecj-11500	63	8	perioperative	perioperative	ADJ
ecj-11500	63	9	bleeding	bleeding	NOUN
ecj-11500	63	10	,	,	PUNCT
ecj-11500	63	11	both	both	CCONJ
ecj-11500	63	12	as	as	ADP
ecj-11500	63	13	a	a	DET
ecj-11500	63	14	prophylactic	prophylactic	ADJ
ecj-11500	63	15	measure	measure	NOUN
ecj-11500	63	16	and	and	CCONJ
ecj-11500	63	17	as	as	ADP
ecj-11500	63	18	a	a	DET
ecj-11500	63	19	treatment.13	treatment.13	NOUN
ecj-11500	63	20	trauma	trauma	NOUN
ecj-11500	63	21	setting	setting	NOUN
ecj-11500	63	22	:	:	PUNCT
ecj-11500	63	23	especially	especially	ADV
ecj-11500	63	24	when	when	SCONJ
ecj-11500	63	25	paired	pair	VERB
ecj-11500	63	26	with	with	ADP
ecj-11500	63	27	ffp	ffp	PROPN
ecj-11500	63	28	,	,	PUNCT
ecj-11500	63	29	pcc	pcc	PROPN
ecj-11500	63	30	can	can	AUX
ecj-11500	63	31	be	be	AUX
ecj-11500	63	32	effective	effective	ADJ
ecj-11500	63	33	in	in	ADP
ecj-11500	63	34	trauma	trauma	NOUN
ecj-11500	63	35	scenarios	scenario	NOUN
ecj-11500	63	36	requiring	require	VERB
ecj-11500	63	37	massive	massive	ADJ
ecj-11500	63	38	transfusions	transfusion	NOUN
ecj-11500	63	39	.	.	PUNCT
ecj-11500	64	1	however	however	ADV
ecj-11500	64	2	,	,	PUNCT
ecj-11500	64	3	its	its	PRON
ecj-11500	64	4	lack	lack	NOUN
ecj-11500	64	5	of	of	ADP
ecj-11500	64	6	factor	factor	NOUN
ecj-11500	64	7	v	v	NOUN
ecj-11500	64	8	can	can	AUX
ecj-11500	64	9	sometimes	sometimes	ADV
ecj-11500	64	10	limit	limit	VERB
ecj-11500	64	11	its	its	PRON
ecj-11500	64	12	standalone	standalone	NOUN
ecj-11500	64	13	efficacy.14	efficacy.14	NOUN
ecj-11500	64	14	activated	activate	VERB
ecj-11500	64	15	four	four	NUM
ecj-11500	64	16	-	-	PUNCT
ecj-11500	64	17	factor	factor	NOUN
ecj-11500	64	18	prothrombin	prothrombin	NOUN
ecj-11500	64	19	complex	complex	NOUN
ecj-11500	64	20	(	(	PUNCT
ecj-11500	64	21	feiba	feiba	NOUN
ecj-11500	64	22	)	)	PUNCT
ecj-11500	64	23	in	in	ADP
ecj-11500	64	24	the	the	DET
ecj-11500	64	25	context	context	NOUN
ecj-11500	64	26	of	of	ADP
ecj-11500	64	27	doac	doac	ADV
ecj-11500	64	28	-	-	PUNCT
ecj-11500	64	29	associated	associate	VERB
ecj-11500	64	30	bleeding	bleeding	NOUN
ecj-11500	64	31	activated	activate	VERB
ecj-11500	64	32	four	four	NUM
ecj-11500	64	33	-	-	PUNCT
ecj-11500	64	34	factor	factor	NOUN
ecj-11500	64	35	prothrombin	prothrombin	NOUN
ecj-11500	64	36	complex	complex	NOUN
ecj-11500	64	37	,	,	PUNCT
ecj-11500	64	38	better	well	ADV
ecj-11500	64	39	known	know	VERB
ecj-11500	64	40	as	as	ADP
ecj-11500	64	41	factor	factor	NOUN
ecj-11500	64	42	eight	eight	NUM
ecj-11500	64	43	inhibitor	inhibitor	NOUN
ecj-11500	64	44	bypassing	bypass	VERB
ecj-11500	64	45	activity	activity	NOUN
ecj-11500	64	46	(	(	PUNCT
ecj-11500	64	47	feiba	feiba	NOUN
ecj-11500	64	48	)	)	PUNCT
ecj-11500	64	49	,	,	PUNCT
ecj-11500	64	50	stands	stand	VERB
ecj-11500	64	51	as	as	ADP
ecj-11500	64	52	a	a	DET
ecj-11500	64	53	pivotal	pivotal	ADJ
ecj-11500	64	54	therapeutic	therapeutic	ADJ
ecj-11500	64	55	agent	agent	NOUN
ecj-11500	64	56	in	in	ADP
ecj-11500	64	57	the	the	DET
ecj-11500	64	58	domain	domain	NOUN
ecj-11500	64	59	of	of	ADP
ecj-11500	64	60	bleeding	bleed	VERB
ecj-11500	64	61	disorder	disorder	NOUN
ecj-11500	64	62	management	management	NOUN
ecj-11500	64	63	.	.	PUNCT
ecj-11500	65	1	it	it	PRON
ecj-11500	65	2	assumes	assume	VERB
ecj-11500	65	3	particular	particular	ADJ
ecj-11500	65	4	significance	significance	NOUN
ecj-11500	65	5	when	when	SCONJ
ecj-11500	65	6	addressing	address	VERB
ecj-11500	65	7	anticoagulant	anticoagulant	NOUN
ecj-11500	65	8	-	-	PUNCT
ecj-11500	65	9	associated	associate	VERB
ecj-11500	65	10	major	major	ADJ
ecj-11500	65	11	or	or	CCONJ
ecj-11500	65	12	life	life	NOUN
ecj-11500	65	13	-	-	PUNCT
ecj-11500	65	14	threatening	threaten	VERB
ecj-11500	65	15	bleedings	bleeding	NOUN
ecj-11500	65	16	.	.	PUNCT
ecj-11500	66	1	comprising	comprise	VERB
ecj-11500	66	2	factors	factor	NOUN
ecj-11500	66	3	ii	ii	PROPN
ecj-11500	66	4	,	,	PUNCT
ecj-11500	66	5	vii	vii	PROPN
ecj-11500	66	6	,	,	PUNCT
ecj-11500	66	7	ix	ix	ADV
ecj-11500	66	8	,	,	PUNCT
ecj-11500	66	9	and	and	CCONJ
ecj-11500	66	10	x	x	X
ecj-11500	66	11	–	–	PUNCT
ecj-11500	66	12	much	much	ADV
ecj-11500	66	13	like	like	ADP
ecj-11500	66	14	pcc4	pcc4	PROPN
ecj-11500	66	15	–	–	PUNCT
ecj-11500	66	16	feiba	feiba	PROPN
ecj-11500	66	17	’s	’s	PART
ecj-11500	66	18	distinctive	distinctive	ADJ
ecj-11500	66	19	feature	feature	NOUN
ecj-11500	66	20	is	be	AUX
ecj-11500	66	21	the	the	DET
ecj-11500	66	22	inclusion	inclusion	NOUN
ecj-11500	66	23	of	of	ADP
ecj-11500	66	24	activated	activate	VERB
ecj-11500	66	25	factor	factor	NOUN
ecj-11500	66	26	vii	vii	PROPN
ecj-11500	66	27	.	.	PUNCT
ecj-11500	67	1	while	while	SCONJ
ecj-11500	67	2	direct	direct	ADJ
ecj-11500	67	3	oral	oral	ADJ
ecj-11500	67	4	anticoagulants	anticoagulant	NOUN
ecj-11500	67	5	(	(	PUNCT
ecj-11500	67	6	doacs	doac	NOUN
ecj-11500	67	7	)	)	PUNCT
ecj-11500	67	8	like	like	ADP
ecj-11500	67	9	dabigatran	dabigatran	ADV
ecj-11500	67	10	,	,	PUNCT
ecj-11500	67	11	rivaroxaban	rivaroxaban	NOUN
ecj-11500	67	12	,	,	PUNCT
ecj-11500	67	13	apixaban	apixaban	ADJ
ecj-11500	67	14	,	,	PUNCT
ecj-11500	67	15	and	and	CCONJ
ecj-11500	67	16	edoxaban	edoxaban	PROPN
ecj-11500	67	17	,	,	PUNCT
ecj-11500	67	18	have	have	AUX
ecj-11500	67	19	been	be	AUX
ecj-11500	67	20	progressively	progressively	ADV
ecj-11500	67	21	endorsed	endorse	VERB
ecj-11500	67	22	as	as	ADP
ecj-11500	67	23	suitable	suitable	ADJ
ecj-11500	67	24	alternatives	alternative	NOUN
ecj-11500	67	25	to	to	ADP
ecj-11500	67	26	traditional	traditional	ADJ
ecj-11500	67	27	vitamin	vitamin	NOUN
ecj-11500	67	28	k	k	PROPN
ecj-11500	67	29	antagonists	antagonist	NOUN
ecj-11500	67	30	,	,	PUNCT
ecj-11500	67	31	they	they	PRON
ecj-11500	67	32	come	come	VERB
ecj-11500	67	33	with	with	ADP
ecj-11500	67	34	challenges	challenge	NOUN
ecj-11500	67	35	.	.	PUNCT
ecj-11500	68	1	chief	chief	NOUN
ecj-11500	68	2	among	among	ADP
ecj-11500	68	3	these	these	PRON
ecj-11500	68	4	is	be	AUX
ecj-11500	68	5	the	the	DET
ecj-11500	68	6	management	management	NOUN
ecj-11500	68	7	of	of	ADP
ecj-11500	68	8	bleeding	bleed	VERB
ecj-11500	68	9	episodes	episode	NOUN
ecj-11500	68	10	,	,	PUNCT
ecj-11500	68	11	especially	especially	ADV
ecj-11500	68	12	when	when	SCONJ
ecj-11500	68	13	specific	specific	ADJ
ecj-11500	68	14	reversal	reversal	NOUN
ecj-11500	68	15	agents	agent	NOUN
ecj-11500	68	16	are	be	AUX
ecj-11500	68	17	unavailable	unavailable	ADJ
ecj-11500	68	18	or	or	CCONJ
ecj-11500	68	19	when	when	SCONJ
ecj-11500	68	20	there	there	PRON
ecj-11500	68	21	’s	’	VERB
ecj-11500	68	22	an	an	DET
ecj-11500	68	23	inability	inability	NOUN
ecj-11500	68	24	to	to	PART
ecj-11500	68	25	standardize	standardize	VERB
ecj-11500	68	26	laboratory	laboratory	NOUN
ecj-11500	68	27	assessments	assessment	NOUN
ecj-11500	68	28	for	for	ADP
ecj-11500	68	29	their	their	PRON
ecj-11500	68	30	anticoagulant	anticoagulant	ADJ
ecj-11500	68	31	effects	effect	NOUN
ecj-11500	68	32	.	.	PUNCT
ecj-11500	69	1	in	in	ADP
ecj-11500	69	2	this	this	DET
ecj-11500	69	3	context	context	NOUN
ecj-11500	69	4	,	,	PUNCT
ecj-11500	69	5	feiba	feiba	PROPN
ecj-11500	69	6	has	have	AUX
ecj-11500	69	7	demonstrated	demonstrate	VERB
ecj-11500	69	8	efficacy	efficacy	NOUN
ecj-11500	69	9	in	in	ADP
ecj-11500	69	10	counteracting	counteract	VERB
ecj-11500	69	11	the	the	DET
ecj-11500	69	12	anticoagulant	anticoagulant	ADJ
ecj-11500	69	13	effects	effect	NOUN
ecj-11500	69	14	of	of	ADP
ecj-11500	69	15	doacs	doac	NOUN
ecj-11500	69	16	.	.	PUNCT
ecj-11500	70	1	this	this	DET
ecj-11500	70	2	breakthrough	breakthrough	NOUN
ecj-11500	70	3	is	be	AUX
ecj-11500	70	4	particularly	particularly	ADV
ecj-11500	70	5	salient	salient	NOUN
ecj-11500	70	6	given	give	VERB
ecj-11500	70	7	the	the	DET
ecj-11500	70	8	burgeoning	burgeon	VERB
ecj-11500	70	9	clinical	clinical	ADJ
ecj-11500	70	10	reliance	reliance	NOUN
ecj-11500	70	11	on	on	ADP
ecj-11500	70	12	these	these	DET
ecj-11500	70	13	agents	agent	NOUN
ecj-11500	70	14	and	and	CCONJ
ecj-11500	70	15	the	the	DET
ecj-11500	70	16	concomitant	concomitant	ADJ
ecj-11500	70	17	risk	risk	NOUN
ecj-11500	70	18	they	they	PRON
ecj-11500	70	19	pose	pose	VERB
ecj-11500	70	20	for	for	ADP
ecj-11500	70	21	major	major	ADJ
ecj-11500	70	22	and	and	CCONJ
ecj-11500	70	23	life	life	NOUN
ecj-11500	70	24	-	-	PUNCT
ecj-11500	70	25	threatening	threaten	VERB
ecj-11500	70	26	bleedings	bleeding	NOUN
ecj-11500	70	27	.	.	PUNCT
ecj-11500	71	1	nevertheless	nevertheless	ADV
ecj-11500	71	2	,	,	PUNCT
ecj-11500	71	3	the	the	DET
ecj-11500	71	4	therapeutic	therapeutic	ADJ
ecj-11500	71	5	landscape	landscape	NOUN
ecj-11500	71	6	with	with	ADP
ecj-11500	71	7	feiba	feiba	PROPN
ecj-11500	71	8	is	be	AUX
ecj-11500	71	9	n’t	not	PART
ecj-11500	71	10	devoid	devoid	ADJ
ecj-11500	71	11	of	of	ADP
ecj-11500	71	12	challenges	challenge	NOUN
ecj-11500	71	13	.	.	PUNCT
ecj-11500	72	1	mirroring	mirror	VERB
ecj-11500	72	2	the	the	DET
ecj-11500	72	3	concerns	concern	NOUN
ecj-11500	72	4	with	with	ADP
ecj-11500	72	5	pcc4	pcc4	PROPN
ecj-11500	72	6	,	,	PUNCT
ecj-11500	72	7	feiba	feiba	PROPN
ecj-11500	72	8	administration	administration	NOUN
ecj-11500	72	9	is	be	AUX
ecj-11500	72	10	shadowed	shadow	VERB
ecj-11500	72	11	by	by	ADP
ecj-11500	72	12	the	the	DET
ecj-11500	72	13	potential	potential	ADJ
ecj-11500	72	14	risk	risk	NOUN
ecj-11500	72	15	of	of	ADP
ecj-11500	72	16	thromboembolic	thromboembolic	ADJ
ecj-11500	72	17	events	event	NOUN
ecj-11500	72	18	,	,	PUNCT
ecj-11500	72	19	underscoring	underscore	VERB
ecj-11500	72	20	the	the	DET
ecj-11500	72	21	need	need	NOUN
ecj-11500	72	22	for	for	ADP
ecj-11500	72	23	judicious	judicious	ADJ
ecj-11500	72	24	application	application	NOUN
ecj-11500	72	25	and	and	CCONJ
ecj-11500	72	26	vigilant	vigilant	ADJ
ecj-11500	72	27	monitoring	monitoring	NOUN
ecj-11500	72	28	.	.	PUNCT
ecj-11500	73	1	as	as	SCONJ
ecj-11500	73	2	the	the	DET
ecj-11500	73	3	medical	medical	ADJ
ecj-11500	73	4	community	community	NOUN
ecj-11500	73	5	grapples	grapple	VERB
ecj-11500	73	6	with	with	ADP
ecj-11500	73	7	the	the	DET
ecj-11500	73	8	absence	absence	NOUN
ecj-11500	73	9	of	of	ADP
ecj-11500	73	10	specific	specific	ADJ
ecj-11500	73	11	reversal	reversal	NOUN
ecj-11500	73	12	antidotes	antidote	NOUN
ecj-11500	73	13	for	for	ADP
ecj-11500	73	14	doacs	doac	NOUN
ecj-11500	73	15	,	,	PUNCT
ecj-11500	73	16	feiba	feiba	PROPN
ecj-11500	73	17	emerges	emerge	VERB
ecj-11500	73	18	as	as	ADP
ecj-11500	73	19	a	a	DET
ecj-11500	73	20	beacon	beacon	NOUN
ecj-11500	73	21	of	of	ADP
ecj-11500	73	22	hope	hope	NOUN
ecj-11500	73	23	,	,	PUNCT
ecj-11500	73	24	albeit	albeit	SCONJ
ecj-11500	73	25	one	one	NUM
ecj-11500	73	26	that	that	PRON
ecj-11500	73	27	necessitates	necessitate	VERB
ecj-11500	73	28	an	an	DET
ecj-11500	73	29	evidenceinformed	evidenceinformed	ADJ
ecj-11500	73	30	,	,	PUNCT
ecj-11500	73	31	multidisciplinary	multidisciplinary	ADJ
ecj-11500	73	32	strategy	strategy	NOUN
ecj-11500	73	33	to	to	PART
ecj-11500	73	34	ensure	ensure	VERB
ecj-11500	73	35	its	its	PRON
ecj-11500	73	36	optimal	optimal	ADJ
ecj-11500	73	37	and	and	CCONJ
ecj-11500	73	38	safe	safe	ADJ
ecj-11500	73	39	application	application	NOUN
ecj-11500	73	40	in	in	ADP
ecj-11500	73	41	clinical	clinical	ADJ
ecj-11500	73	42	scenarios.9	scenarios.9	NOUN
ecj-11500	73	43	-	-	PUNCT
ecj-11500	73	44	15	15	NUM
ecj-11500	73	45	factor	factor	NOUN
ecj-11500	73	46	vii	vii	PROPN
ecj-11500	73	47	factor	factor	NOUN
ecj-11500	73	48	vii	vii	PROPN
ecj-11500	73	49	(	(	PUNCT
ecj-11500	73	50	fvii	fvii	PROPN
ecj-11500	73	51	)	)	PUNCT
ecj-11500	73	52	,	,	PUNCT
ecj-11500	73	53	a	a	DET
ecj-11500	73	54	vitamin	vitamin	NOUN
ecj-11500	73	55	k	k	NOUN
ecj-11500	73	56	-	-	ADJ
ecj-11500	73	57	dependent	dependent	ADJ
ecj-11500	73	58	glycoprotein	glycoprotein	NOUN
ecj-11500	73	59	primarily	primarily	ADV
ecj-11500	73	60	synthesized	synthesize	VERB
ecj-11500	73	61	in	in	ADP
ecj-11500	73	62	the	the	DET
ecj-11500	73	63	liver	liver	NOUN
ecj-11500	73	64	,	,	PUNCT
ecj-11500	73	65	plays	play	VERB
ecj-11500	73	66	a	a	DET
ecj-11500	73	67	crucial	crucial	ADJ
ecj-11500	73	68	role	role	NOUN
ecj-11500	73	69	in	in	ADP
ecj-11500	73	70	the	the	DET
ecj-11500	73	71	initiation	initiation	NOUN
ecj-11500	73	72	of	of	ADP
ecj-11500	73	73	the	the	DET
ecj-11500	73	74	extrinsic	extrinsic	ADJ
ecj-11500	73	75	coagulation	coagulation	NOUN
ecj-11500	73	76	pathway	pathway	NOUN
ecj-11500	73	77	.	.	PUNCT
ecj-11500	74	1	it	it	PRON
ecj-11500	74	2	circulates	circulate	VERB
ecj-11500	74	3	within	within	ADP
ecj-11500	74	4	the	the	DET
ecj-11500	74	5	bloodstream	bloodstream	NOUN
ecj-11500	74	6	in	in	ADP
ecj-11500	74	7	both	both	CCONJ
ecj-11500	74	8	its	its	PRON
ecj-11500	74	9	zymogen	zymogen	NOUN
ecj-11500	74	10	and	and	CCONJ
ecj-11500	74	11	activated	activated	ADJ
ecj-11500	74	12	forms	form	NOUN
ecj-11500	74	13	.	.	PUNCT
ecj-11500	75	1	upon	upon	SCONJ
ecj-11500	75	2	vascular	vascular	ADJ
ecj-11500	75	3	injury	injury	NOUN
ecj-11500	75	4	,	,	PUNCT
ecj-11500	75	5	tissue	tissue	NOUN
ecj-11500	75	6	factor	factor	NOUN
ecj-11500	75	7	(	(	PUNCT
ecj-11500	75	8	tf	tf	PROPN
ecj-11500	75	9	)	)	PUNCT
ecj-11500	75	10	–	–	PUNCT
ecj-11500	75	11	a	a	DET
ecj-11500	75	12	transmembrane	transmembrane	ADJ
ecj-11500	75	13	protein	protein	NOUN
ecj-11500	75	14	from	from	ADP
ecj-11500	75	15	subendothelial	subendothelial	ADJ
ecj-11500	75	16	cells	cell	NOUN
ecj-11500	75	17	–	–	PUNCT
ecj-11500	75	18	becomes	becomes	AUX
ecj-11500	75	19	exposed	expose	VERB
ecj-11500	75	20	to	to	ADP
ecj-11500	75	21	blood	blood	NOUN
ecj-11500	75	22	flow	flow	NOUN
ecj-11500	75	23	.	.	PUNCT
ecj-11500	76	1	this	this	DET
ecj-11500	76	2	interaction	interaction	NOUN
ecj-11500	76	3	catalyzes	catalyze	VERB
ecj-11500	76	4	the	the	DET
ecj-11500	76	5	transformation	transformation	NOUN
ecj-11500	76	6	of	of	ADP
ecj-11500	76	7	fvii	fvii	ADJ
ecj-11500	76	8	to	to	ADP
ecj-11500	76	9	its	its	PRON
ecj-11500	76	10	active	active	ADJ
ecj-11500	76	11	form	form	NOUN
ecj-11500	76	12	,	,	PUNCT
ecj-11500	76	13	factor	factor	NOUN
ecj-11500	76	14	viia	viia	NOUN
ecj-11500	76	15	.	.	PUNCT
ecj-11500	77	1	subsequently	subsequently	ADV
ecj-11500	77	2	,	,	PUNCT
ecj-11500	77	3	the	the	DET
ecj-11500	77	4	tf	tf	ADJ
ecj-11500	77	5	-	-	PUNCT
ecj-11500	77	6	fviia	fviia	NOUN
ecj-11500	77	7	complex	complex	NOUN
ecj-11500	77	8	activates	activate	VERB
ecj-11500	77	9	both	both	DET
ecj-11500	77	10	factor	factor	NOUN
ecj-11500	77	11	ix	ix	ADV
ecj-11500	77	12	and	and	CCONJ
ecj-11500	77	13	factor	factor	NOUN
ecj-11500	77	14	x	x	NOUN
ecj-11500	77	15	,	,	PUNCT
ecj-11500	77	16	instigating	instigate	VERB
ecj-11500	77	17	a	a	DET
ecj-11500	77	18	cascade	cascade	NOUN
ecj-11500	77	19	that	that	PRON
ecj-11500	77	20	culminates	culminate	VERB
ecj-11500	77	21	in	in	ADP
ecj-11500	77	22	fibrin	fibrin	NOUN
ecj-11500	77	23	clot	clot	NOUN
ecj-11500	77	24	formation.16	formation.16	PROPN
ecj-11500	77	25	individuals	individual	NOUN
ecj-11500	77	26	with	with	ADP
ecj-11500	77	27	congenital	congenital	ADJ
ecj-11500	77	28	factor	factor	NOUN
ecj-11500	77	29	vii	vii	PROPN
ecj-11500	77	30	deficiency	deficiency	NOUN
ecj-11500	77	31	present	present	VERB
ecj-11500	77	32	a	a	DET
ecj-11500	77	33	bleeding	bleed	VERB
ecj-11500	77	34	phenotype	phenotype	NOUN
ecj-11500	77	35	,	,	PUNCT
ecj-11500	77	36	the	the	DET
ecj-11500	77	37	severity	severity	NOUN
ecj-11500	77	38	of	of	ADP
ecj-11500	77	39	which	which	PRON
ecj-11500	77	40	correlates	correlate	VERB
ecj-11500	77	41	with	with	ADP
ecj-11500	77	42	residual	residual	ADJ
ecj-11500	77	43	factor	factor	NOUN
ecj-11500	77	44	vii	vii	NOUN
ecj-11500	77	45	activity	activity	NOUN
ecj-11500	77	46	levels	level	NOUN
ecj-11500	77	47	.	.	PUNCT
ecj-11500	78	1	the	the	DET
ecj-11500	78	2	management	management	NOUN
ecj-11500	78	3	of	of	ADP
ecj-11500	78	4	such	such	ADJ
ecj-11500	78	5	individuals	individual	NOUN
ecj-11500	78	6	necessitates	necessitate	VERB
ecj-11500	78	7	factor	factor	NOUN
ecj-11500	78	8	vii	vii	PROPN
ecj-11500	78	9	replenishment	replenishment	PROPN
ecj-11500	78	10	.	.	PUNCT
ecj-11500	79	1	historically	historically	ADV
ecj-11500	79	2	,	,	PUNCT
ecj-11500	79	3	prothrombin	prothrombin	ADJ
ecj-11500	79	4	complex	complex	ADJ
ecj-11500	79	5	concentrates	concentrate	NOUN
ecj-11500	79	6	(	(	PUNCT
ecj-11500	79	7	pcc3	pcc3	NOUN
ecj-11500	79	8	and	and	CCONJ
ecj-11500	79	9	pcc4	pcc4	PROPN
ecj-11500	79	10	)	)	PUNCT
ecj-11500	79	11	were	be	AUX
ecj-11500	79	12	utilized	utilize	VERB
ecj-11500	79	13	for	for	ADP
ecj-11500	79	14	this	this	DET
ecj-11500	79	15	purpose	purpose	NOUN
ecj-11500	79	16	.	.	PUNCT
ecj-11500	80	1	however	however	ADV
ecj-11500	80	2	,	,	PUNCT
ecj-11500	80	3	these	these	DET
ecj-11500	80	4	solutions	solution	NOUN
ecj-11500	80	5	often	often	ADV
ecj-11500	80	6	fell	fall	VERB
ecj-11500	80	7	short	short	ADJ
ecj-11500	80	8	in	in	ADP
ecj-11500	80	9	providing	provide	VERB
ecj-11500	80	10	ample	ample	ADJ
ecj-11500	80	11	factor	factor	NOUN
ecj-11500	80	12	vii	vii	PROPN
ecj-11500	80	13	.	.	PUNCT
ecj-11500	81	1	this	this	DET
ecj-11500	81	2	gap	gap	NOUN
ecj-11500	81	3	in	in	ADP
ecj-11500	81	4	therapeutic	therapeutic	ADJ
ecj-11500	81	5	management	management	NOUN
ecj-11500	81	6	led	lead	VERB
ecj-11500	81	7	to	to	ADP
ecj-11500	81	8	the	the	DET
ecj-11500	81	9	introduction	introduction	NOUN
ecj-11500	81	10	of	of	ADP
ecj-11500	81	11	non	non	ADJ
ecj-11500	81	12	-	-	ADJ
ecj-11500	81	13	activated	activated	ADJ
ecj-11500	81	14	factor	factor	NOUN
ecj-11500	81	15	vii	vii	PROPN
ecj-11500	81	16	as	as	ADP
ecj-11500	81	17	a	a	DET
ecj-11500	81	18	targeted	target	VERB
ecj-11500	81	19	therapeutic	therapeutic	ADJ
ecj-11500	81	20	agent	agent	NOUN
ecj-11500	81	21	,	,	PUNCT
ecj-11500	81	22	specifically	specifically	ADV
ecj-11500	81	23	tailored	tailor	VERB
ecj-11500	81	24	for	for	ADP
ecj-11500	81	25	patients	patient	NOUN
ecj-11500	81	26	with	with	ADP
ecj-11500	81	27	isolated	isolated	ADJ
ecj-11500	81	28	factor	factor	NOUN
ecj-11500	81	29	vii	vii	NOUN
ecj-11500	81	30	deficiency	deficiency	NOUN
ecj-11500	81	31	.	.	PUNCT
ecj-11500	82	1	this	this	DET
ecj-11500	82	2	advancement	advancement	NOUN
ecj-11500	82	3	ensures	ensure	VERB
ecj-11500	82	4	the	the	DET
ecj-11500	82	5	delivery	delivery	NOUN
ecj-11500	82	6	of	of	ADP
ecj-11500	82	7	precise	precise	ADJ
ecj-11500	82	8	factor	factor	NOUN
ecj-11500	82	9	vii	vii	PROPN
ecj-11500	82	10	dosages	dosage	NOUN
ecj-11500	82	11	,	,	PUNCT
ecj-11500	82	12	effectively	effectively	ADV
ecj-11500	82	13	mitigating	mitigate	VERB
ecj-11500	82	14	bleeding	bleeding	NOUN
ecj-11500	82	15	risks	risk	NOUN
ecj-11500	82	16	.	.	PUNCT
ecj-11500	83	1	moreover	moreover	ADV
ecj-11500	83	2	,	,	PUNCT
ecj-11500	83	3	recombinant	recombinant	ADJ
ecj-11500	83	4	activated	activate	VERB
ecj-11500	83	5	factor	factor	NOUN
ecj-11500	83	6	vii	vii	PROPN
ecj-11500	83	7	(	(	PUNCT
ecj-11500	83	8	rfviia	rfviia	PROPN
ecj-11500	83	9	)	)	PUNCT
ecj-11500	83	10	offers	offer	VERB
ecj-11500	83	11	a	a	DET
ecj-11500	83	12	distinct	distinct	ADJ
ecj-11500	83	13	therapeutic	therapeutic	ADJ
ecj-11500	83	14	approach	approach	NOUN
ecj-11500	83	15	.	.	PUNCT
ecj-11500	84	1	it	it	PRON
ecj-11500	84	2	emulates	emulate	VERB
ecj-11500	84	3	the	the	DET
ecj-11500	84	4	action	action	NOUN
ecj-11500	84	5	of	of	ADP
ecj-11500	84	6	endogenous	endogenous	ADJ
ecj-11500	84	7	factor	factor	NOUN
ecj-11500	84	8	viia	viia	NOUN
ecj-11500	84	9	,	,	PUNCT
ecj-11500	84	10	directly	directly	ADV
ecj-11500	84	11	activating	activate	VERB
ecj-11500	84	12	factor	factor	NOUN
ecj-11500	84	13	x	x	NOUN
ecj-11500	84	14	in	in	ADP
ecj-11500	84	15	the	the	DET
ecj-11500	84	16	presence	presence	NOUN
ecj-11500	84	17	of	of	ADP
ecj-11500	84	18	tf	tf	PROPN
ecj-11500	84	19	without	without	ADP
ecj-11500	84	20	necessitating	necessitate	VERB
ecj-11500	84	21	factors	factor	NOUN
ecj-11500	84	22	viii	viii	ADJ
ecj-11500	84	23	and	and	CCONJ
ecj-11500	84	24	ix	ix	ADV
ecj-11500	84	25	.	.	PUNCT
ecj-11500	85	1	this	this	DET
ecj-11500	85	2	unique	unique	ADJ
ecj-11500	85	3	mechanism	mechanism	NOUN
ecj-11500	85	4	has	have	AUX
ecj-11500	85	5	expanded	expand	VERB
ecj-11500	85	6	its	its	PRON
ecj-11500	85	7	application	application	NOUN
ecj-11500	85	8	spectrum	spectrum	NOUN
ecj-11500	85	9	,	,	PUNCT
ecj-11500	85	10	making	make	VERB
ecj-11500	85	11	it	it	PRON
ecj-11500	85	12	suitable	suitable	ADJ
ecj-11500	85	13	not	not	PART
ecj-11500	85	14	just	just	ADV
ecj-11500	85	15	for	for	ADP
ecj-11500	85	16	factor	factor	NOUN
ecj-11500	85	17	vii	vii	NOUN
ecj-11500	85	18	deficiency	deficiency	NOUN
ecj-11500	85	19	but	but	CCONJ
ecj-11500	85	20	also	also	ADV
ecj-11500	85	21	other	other	ADJ
ecj-11500	85	22	bleeding	bleed	VERB
ecj-11500	85	23	disorders	disorder	NOUN
ecj-11500	85	24	where	where	SCONJ
ecj-11500	85	25	traditional	traditional	ADJ
ecj-11500	85	26	treatments	treatment	NOUN
ecj-11500	85	27	might	might	AUX
ecj-11500	85	28	be	be	AUX
ecj-11500	85	29	inadequate	inadequate	ADJ
ecj-11500	85	30	.	.	PUNCT
ecj-11500	86	1	notably	notably	ADV
ecj-11500	86	2	,	,	PUNCT
ecj-11500	86	3	individual	individual	ADJ
ecj-11500	86	4	responses	response	NOUN
ecj-11500	86	5	can	can	AUX
ecj-11500	86	6	vary	vary	VERB
ecj-11500	86	7	even	even	ADV
ecj-11500	86	8	among	among	ADP
ecj-11500	86	9	patients	patient	NOUN
ecj-11500	86	10	with	with	ADP
ecj-11500	86	11	similar	similar	ADJ
ecj-11500	86	12	factor	factor	NOUN
ecj-11500	86	13	vii	vii	NOUN
ecj-11500	86	14	activity	activity	NOUN
ecj-11500	86	15	levels	level	NOUN
ecj-11500	86	16	,	,	PUNCT
ecj-11500	86	17	hinting	hint	VERB
ecj-11500	86	18	at	at	ADP
ecj-11500	86	19	the	the	DET
ecj-11500	86	20	influence	influence	NOUN
ecj-11500	86	21	of	of	ADP
ecj-11500	86	22	other	other	ADJ
ecj-11500	86	23	genetic	genetic	ADJ
ecj-11500	86	24	and	and	CCONJ
ecj-11500	86	25	environmental	environmental	ADJ
ecj-11500	86	26	factors	factor	NOUN
ecj-11500	86	27	on	on	ADP
ecj-11500	86	28	clinical	clinical	ADJ
ecj-11500	86	29	presentation	presentation	NOUN
ecj-11500	86	30	.	.	PUNCT
ecj-11500	87	1	comparison	comparison	NOUN
ecj-11500	87	2	of	of	ADP
ecj-11500	87	3	three	three	NUM
ecj-11500	87	4	-	-	PUNCT
ecj-11500	87	5	factor	factor	NOUN
ecj-11500	87	6	and	and	CCONJ
ecj-11500	87	7	four	four	NUM
ecj-11500	87	8	-	-	PUNCT
ecj-11500	87	9	factor	factor	NOUN
ecj-11500	87	10	prothrombin	prothrombin	NOUN
ecj-11500	87	11	complex	complex	NOUN
ecj-11500	87	12	the	the	DET
ecj-11500	87	13	choice	choice	NOUN
ecj-11500	87	14	between	between	ADP
ecj-11500	87	15	three	three	NUM
ecj-11500	87	16	-	-	PUNCT
ecj-11500	87	17	factor	factor	NOUN
ecj-11500	87	18	(	(	PUNCT
ecj-11500	87	19	pcc3	pcc3	PROPN
ecj-11500	87	20	)	)	PUNCT
ecj-11500	87	21	and	and	CCONJ
ecj-11500	87	22	four	four	NUM
ecj-11500	87	23	-	-	PUNCT
ecj-11500	87	24	factor	factor	NOUN
ecj-11500	87	25	prothrombin	prothrombin	NOUN
ecj-11500	87	26	complex	complex	ADJ
ecj-11500	87	27	concentrate	concentrate	NOUN
ecj-11500	87	28	(	(	PUNCT
ecj-11500	87	29	pcc4	pcc4	PROPN
ecj-11500	87	30	)	)	PUNCT
ecj-11500	87	31	is	be	AUX
ecj-11500	87	32	often	often	ADV
ecj-11500	87	33	dictated	dictate	VERB
ecj-11500	87	34	by	by	ADP
ecj-11500	87	35	the	the	DET
ecj-11500	87	36	clinical	clinical	ADJ
ecj-11500	87	37	context	context	NOUN
ecj-11500	87	38	,	,	PUNCT
ecj-11500	87	39	the	the	DET
ecj-11500	87	40	specific	specific	ADJ
ecj-11500	87	41	coagulation	coagulation	NOUN
ecj-11500	87	42	factor	factor	NOUN
ecj-11500	87	43	deficiencies	deficiency	NOUN
ecj-11500	87	44	present	present	ADJ
ecj-11500	87	45	,	,	PUNCT
ecj-11500	87	46	and	and	CCONJ
ecj-11500	87	47	the	the	DET
ecj-11500	87	48	risk	risk	NOUN
ecj-11500	87	49	of	of	ADP
ecj-11500	87	50	potential	potential	ADJ
ecj-11500	87	51	adverse	adverse	ADJ
ecj-11500	87	52	events	event	NOUN
ecj-11500	87	53	.	.	PUNCT
ecj-11500	88	1	both	both	PRON
ecj-11500	88	2	pcc3	pcc3	NOUN
ecj-11500	88	3	and	and	CCONJ
ecj-11500	88	4	pcc4	pcc4	PROPN
ecj-11500	88	5	have	have	AUX
ecj-11500	88	6	been	be	AUX
ecj-11500	88	7	shown	show	VERB
ecj-11500	88	8	to	to	PART
ecj-11500	88	9	be	be	AUX
ecj-11500	88	10	effective	effective	ADJ
ecj-11500	88	11	in	in	ADP
ecj-11500	88	12	the	the	DET
ecj-11500	88	13	management	management	NOUN
ecj-11500	88	14	of	of	ADP
ecj-11500	88	15	bleeding	bleed	VERB
ecj-11500	88	16	disorders	disorder	NOUN
ecj-11500	88	17	,	,	PUNCT
ecj-11500	88	18	particularly	particularly	ADV
ecj-11500	88	19	in	in	ADP
ecj-11500	88	20	the	the	DET
ecj-11500	88	21	context	context	NOUN
ecj-11500	88	22	of	of	ADP
ecj-11500	88	23	anticoagulant	anticoagulant	NOUN
ecj-11500	88	24	-	-	PUNCT
ecj-11500	88	25	associated	associate	VERB
ecj-11500	88	26	major	major	ADJ
ecj-11500	88	27	or	or	CCONJ
ecj-11500	88	28	life	life	NOUN
ecj-11500	88	29	-	-	PUNCT
ecj-11500	88	30	threatening	threaten	VERB
ecj-11500	88	31	bleeding.9,10	bleeding.9,10	NOUN
ecj-11500	88	32	pcc4	pcc4	PROPN
ecj-11500	88	33	,	,	PUNCT
ecj-11500	88	34	which	which	PRON
ecj-11500	88	35	additionally	additionally	ADV
ecj-11500	88	36	includes	include	VERB
ecj-11500	88	37	factor	factor	NOUN
ecj-11500	88	38	vii	vii	PROPN
ecj-11500	88	39	,	,	PUNCT
ecj-11500	88	40	has	have	AUX
ecj-11500	88	41	been	be	AUX
ecj-11500	88	42	found	find	VERB
ecj-11500	88	43	to	to	PART
ecj-11500	88	44	be	be	AUX
ecj-11500	88	45	more	more	ADV
ecj-11500	88	46	effective	effective	ADJ
ecj-11500	88	47	in	in	ADP
ecj-11500	88	48	achieving	achieve	VERB
ecj-11500	88	49	target	target	NOUN
ecj-11500	88	50	inr	inr	NOUN
ecj-11500	88	51	levels	level	NOUN
ecj-11500	88	52	in	in	ADP
ecj-11500	88	53	patients	patient	NOUN
ecj-11500	88	54	requiring	require	VERB
ecj-11500	88	55	emergent	emergent	ADJ
ecj-11500	88	56	warfarin	warfarin	NOUN
ecj-11500	88	57	reversal	reversal	NOUN
ecj-11500	88	58	.	.	PUNCT
ecj-11500	89	1	this	this	PRON
ecj-11500	89	2	suggests	suggest	VERB
ecj-11500	89	3	a	a	DET
ecj-11500	89	4	potential	potential	ADJ
ecj-11500	89	5	advantage	advantage	NOUN
ecj-11500	89	6	over	over	ADP
ecj-11500	89	7	pcc3	pcc3	NOUN
ecj-11500	89	8	,	,	PUNCT
ecj-11500	89	9	particularly	particularly	ADV
ecj-11500	89	10	in	in	ADP
ecj-11500	89	11	patients	patient	NOUN
ecj-11500	89	12	with	with	ADP
ecj-11500	89	13	deficiencies	deficiency	NOUN
ecj-11500	89	14	or	or	CCONJ
ecj-11500	89	15	functional	functional	ADJ
ecj-11500	89	16	impairments	impairment	NOUN
ecj-11500	89	17	of	of	ADP
ecj-11500	89	18	factor	factor	NOUN
ecj-11500	89	19	vii.10	vii.10	NOUN
ecj-11500	89	20	however	however	ADV
ecj-11500	89	21	,	,	PUNCT
ecj-11500	89	22	both	both	CCONJ
ecj-11500	89	23	pcc3	pcc3	NOUN
ecj-11500	89	24	and	and	CCONJ
ecj-11500	89	25	pcc4	pcc4	PROPN
ecj-11500	89	26	carry	carry	VERB
ecj-11500	89	27	a	a	DET
ecj-11500	89	28	risk	risk	NOUN
ecj-11500	89	29	of	of	ADP
ecj-11500	89	30	thromboembolic	thromboembolic	ADJ
ecj-11500	89	31	events	event	NOUN
ecj-11500	89	32	,	,	PUNCT
ecj-11500	89	33	which	which	PRON
ecj-11500	89	34	remains	remain	VERB
ecj-11500	89	35	a	a	DET
ecj-11500	89	36	significant	significant	ADJ
ecj-11500	89	37	concern	concern	NOUN
ecj-11500	89	38	.	.	PUNCT
ecj-11500	90	1	this	this	PRON
ecj-11500	90	2	necessitates	necessitate	VERB
ecj-11500	90	3	careful	careful	ADJ
ecj-11500	90	4	consideration	consideration	NOUN
ecj-11500	90	5	and	and	CCONJ
ecj-11500	90	6	monitoring	monitoring	NOUN
ecj-11500	90	7	when	when	SCONJ
ecj-11500	90	8	using	use	VERB
ecj-11500	90	9	these	these	DET
ecj-11500	90	10	agents	agent	NOUN
ecj-11500	90	11	.	.	PUNCT
ecj-11500	91	1	the	the	DET
ecj-11500	91	2	risk	risk	NOUN
ecj-11500	91	3	of	of	ADP
ecj-11500	91	4	thromboembolic	thromboembolic	ADJ
ecj-11500	91	5	events	event	NOUN
ecj-11500	91	6	may	may	AUX
ecj-11500	91	7	be	be	AUX
ecj-11500	91	8	influenced	influence	VERB
ecj-11500	91	9	by	by	ADP
ecj-11500	91	10	a	a	DET
ecj-11500	91	11	variety	variety	NOUN
ecj-11500	91	12	of	of	ADP
ecj-11500	91	13	factors	factor	NOUN
ecj-11500	91	14	,	,	PUNCT
ecj-11500	91	15	including	include	VERB
ecj-11500	91	16	the	the	DET
ecj-11500	91	17	patient	patient	NOUN
ecj-11500	91	18	’s	’s	PART
ecj-11500	91	19	underlying	underlie	VERB
ecj-11500	91	20	health	health	NOUN
ecj-11500	91	21	status	status	NOUN
ecj-11500	91	22	,	,	PUNCT
ecj-11500	91	23	the	the	DET
ecj-11500	91	24	presence	presence	NOUN
ecj-11500	91	25	of	of	ADP
ecj-11500	91	26	other	other	ADJ
ecj-11500	91	27	risk	risk	NOUN
ecj-11500	91	28	factors	factor	NOUN
ecj-11500	91	29	for	for	ADP
ecj-11500	91	30	thrombosis	thrombosis	NOUN
ecj-11500	91	31	,	,	PUNCT
ecj-11500	91	32	and	and	CCONJ
ecj-11500	91	33	the	the	DET
ecj-11500	91	34	specific	specific	ADJ
ecj-11500	91	35	clinical	clinical	ADJ
ecj-11500	91	36	context.9,10	context.9,10	NOUN
ecj-11500	91	37	in	in	ADP
ecj-11500	91	38	conclusion	conclusion	NOUN
ecj-11500	91	39	,	,	PUNCT
ecj-11500	91	40	while	while	SCONJ
ecj-11500	91	41	pcc3	pcc3	NOUN
ecj-11500	91	42	,	,	PUNCT
ecj-11500	91	43	pcc4	pcc4	PROPN
ecj-11500	91	44	(	(	PUNCT
ecj-11500	91	45	also	also	ADV
ecj-11500	91	46	feiba	feiba	VERB
ecj-11500	91	47	)	)	PUNCT
ecj-11500	91	48	all	all	PRON
ecj-11500	91	49	play	play	VERB
ecj-11500	91	50	a	a	DET
ecj-11500	91	51	vital	vital	ADJ
ecj-11500	91	52	role	role	NOUN
ecj-11500	91	53	in	in	ADP
ecj-11500	91	54	the	the	DET
ecj-11500	91	55	management	management	NOUN
ecj-11500	91	56	of	of	ADP
ecj-11500	91	57	bleeding	bleed	VERB
ecj-11500	91	58	disorders	disorder	NOUN
ecj-11500	91	59	,	,	PUNCT
ecj-11500	91	60	their	their	PRON
ecj-11500	91	61	use	use	NOUN
ecj-11500	91	62	must	must	AUX
ecj-11500	91	63	be	be	AUX
ecj-11500	91	64	guided	guide	VERB
ecj-11500	91	65	by	by	ADP
ecj-11500	91	66	a	a	DET
ecj-11500	91	67	careful	careful	ADJ
ecj-11500	91	68	assessment	assessment	NOUN
ecj-11500	91	69	of	of	ADP
ecj-11500	91	70	the	the	DET
ecj-11500	91	71	potential	potential	ADJ
ecj-11500	91	72	benefits	benefit	NOUN
ecj-11500	91	73	and	and	CCONJ
ecj-11500	91	74	risks	risk	NOUN
ecj-11500	91	75	in	in	ADP
ecj-11500	91	76	each	each	DET
ecj-11500	91	77	individual	individual	ADJ
ecj-11500	91	78	patient	patient	NOUN
ecj-11500	91	79	’s	’s	PART
ecj-11500	91	80	context.9,10	context.9,10	ADP
ecj-11500	91	81	alternative	alternative	ADJ
ecj-11500	91	82	strategy	strategy	NOUN
ecj-11500	91	83	:	:	PUNCT
ecj-11500	92	1	pcc3	pcc3	NOUN
ecj-11500	92	2	as	as	ADP
ecj-11500	92	3	default	default	NOUN
ecj-11500	92	4	therapy	therapy	NOUN
ecj-11500	92	5	and	and	CCONJ
ecj-11500	92	6	factor	factor	NOUN
ecj-11500	92	7	vii	vii	PROPN
ecj-11500	92	8	as	as	SCONJ
ecj-11500	92	9	needed	need	VERB
ecj-11500	92	10	given	give	VERB
ecj-11500	92	11	the	the	DET
ecj-11500	92	12	costs	cost	NOUN
ecj-11500	92	13	and	and	CCONJ
ecj-11500	92	14	potential	potential	ADJ
ecj-11500	92	15	risks	risk	NOUN
ecj-11500	92	16	associated	associate	VERB
ecj-11500	92	17	with	with	ADP
ecj-11500	92	18	the	the	DET
ecj-11500	92	19	use	use	NOUN
ecj-11500	92	20	of	of	ADP
ecj-11500	92	21	four	four	NUM
ecj-11500	92	22	-	-	PUNCT
ecj-11500	92	23	factor	factor	NOUN
ecj-11500	92	24	prothrombin	prothrombin	NOUN
ecj-11500	92	25	complex	complex	ADJ
ecj-11500	92	26	concentrate	concentrate	NOUN
ecj-11500	92	27	(	(	PUNCT
ecj-11500	92	28	pcc4	pcc4	PROPN
ecj-11500	92	29	)	)	PUNCT
ecj-11500	92	30	,	,	PUNCT
ecj-11500	92	31	an	an	DET
ecj-11500	92	32	alternative	alternative	ADJ
ecj-11500	92	33	and	and	CCONJ
ecj-11500	92	34	more	more	ADJ
ecj-11500	92	35	cost	cost	NOUN
ecj-11500	92	36	-	-	PUNCT
ecj-11500	92	37	effective	effective	ADJ
ecj-11500	92	38	strategy	strategy	NOUN
ecj-11500	92	39	could	could	AUX
ecj-11500	92	40	be	be	AUX
ecj-11500	92	41	to	to	PART
ecj-11500	92	42	employ	employ	VERB
ecj-11500	92	43	three	three	NUM
ecj-11500	92	44	-	-	PUNCT
ecj-11500	92	45	factor	factor	NOUN
ecj-11500	92	46	prothrombin	prothrombin	NOUN
ecj-11500	92	47	complex	complex	ADJ
ecj-11500	92	48	concentrate	concentrate	NOUN
ecj-11500	92	49	(	(	PUNCT
ecj-11500	92	50	pcc3	pcc3	PROPN
ecj-11500	92	51	)	)	PUNCT
ecj-11500	92	52	as	as	ADP
ecj-11500	92	53	a	a	DET
ecj-11500	92	54	foundational	foundational	ADJ
ecj-11500	92	55	therapy	therapy	NOUN
ecj-11500	92	56	,	,	PUNCT
ecj-11500	92	57	supplementing	supplement	VERB
ecj-11500	92	58	with	with	ADP
ecj-11500	92	59	factor	factor	NOUN
ecj-11500	92	60	vii	vii	PROPN
ecj-11500	92	61	based	base	VERB
ecj-11500	92	62	on	on	ADP
ecj-11500	92	63	real	real	ADJ
ecj-11500	92	64	-	-	PUNCT
ecj-11500	92	65	time	time	NOUN
ecj-11500	92	66	coagulation	coagulation	NOUN
ecj-11500	92	67	assessments	assessment	NOUN
ecj-11500	92	68	using	use	VERB
ecj-11500	92	69	thromboelastometry	thromboelastometry	NOUN
ecj-11500	92	70	,	,	PUNCT
ecj-11500	92	71	such	such	ADJ
ecj-11500	92	72	as	as	ADP
ecj-11500	92	73	rotem	rotem	NOUN
ecj-11500	92	74	.	.	PUNCT
ecj-11500	93	1	recent	recent	ADJ
ecj-11500	93	2	clinical	clinical	ADJ
ecj-11500	93	3	instances	instance	NOUN
ecj-11500	93	4	underscore	underscore	VERB
ecj-11500	93	5	the	the	DET
ecj-11500	93	6	potential	potential	NOUN
ecj-11500	93	7	of	of	ADP
ecj-11500	93	8	rotem	rotem	NOUN
ecj-11500	93	9	in	in	ADP
ecj-11500	93	10	guiding	guide	VERB
ecj-11500	93	11	the	the	DET
ecj-11500	93	12	management	management	NOUN
ecj-11500	93	13	of	of	ADP
ecj-11500	93	14	intraoperative	intraoperative	ADJ
ecj-11500	93	15	bleeding	bleeding	NOUN
ecj-11500	93	16	,	,	PUNCT
ecj-11500	93	17	especially	especially	ADV
ecj-11500	93	18	in	in	ADP
ecj-11500	93	19	patients	patient	NOUN
ecj-11500	93	20	with	with	ADP
ecj-11500	93	21	factor	factor	NOUN
ecj-11500	93	22	vii	vii	PROPN
ecj-11500	93	23	deficiency	deficiency	NOUN
ecj-11500	93	24	.	.	PUNCT
ecj-11500	94	1	for	for	ADP
ecj-11500	94	2	instance	instance	NOUN
ecj-11500	94	3	,	,	PUNCT
ecj-11500	94	4	in	in	ADP
ecj-11500	94	5	a	a	DET
ecj-11500	94	6	case	case	NOUN
ecj-11500	94	7	where	where	SCONJ
ecj-11500	94	8	a	a	DET
ecj-11500	94	9	patient	patient	NOUN
ecj-11500	94	10	with	with	ADP
ecj-11500	94	11	factor	factor	NOUN
ecj-11500	94	12	vii	vii	PROPN
ecj-11500	94	13	deficiency	deficiency	NOUN
ecj-11500	94	14	experienced	experience	VERB
ecj-11500	94	15	severe	severe	ADJ
ecj-11500	94	16	intraoperative	intraoperative	ADJ
ecj-11500	94	17	bleeding	bleeding	NOUN
ecj-11500	94	18	,	,	PUNCT
ecj-11500	94	19	rotem	rotem	PROPN
ecj-11500	94	20	played	play	VERB
ecj-11500	94	21	a	a	DET
ecj-11500	94	22	pivotal	pivotal	ADJ
ecj-11500	94	23	role	role	NOUN
ecj-11500	94	24	in	in	ADP
ecj-11500	94	25	determining	determine	VERB
ecj-11500	94	26	the	the	DET
ecj-11500	94	27	need	need	NOUN
ecj-11500	94	28	for	for	ADP
ecj-11500	94	29	,	,	PUNCT
ecj-11500	94	30	and	and	CCONJ
ecj-11500	94	31	subsequently	subsequently	ADV
ecj-11500	94	32	guiding	guide	VERB
ecj-11500	94	33	the	the	DET
ecj-11500	94	34	administration	administration	NOUN
ecj-11500	94	35	of	of	ADP
ecj-11500	94	36	,	,	PUNCT
ecj-11500	94	37	additional	additional	ADJ
ecj-11500	94	38	recombinant	recombinant	ADJ
ecj-11500	94	39	activated	activate	VERB
ecj-11500	94	40	factor	factor	NOUN
ecj-11500	94	41	vii	vii	PROPN
ecj-11500	94	42	(	(	PUNCT
ecj-11500	94	43	rfviia	rfviia	NOUN
ecj-11500	94	44	)	)	PUNCT
ecj-11500	94	45	doses	dose	NOUN
ecj-11500	94	46	,	,	PUNCT
ecj-11500	94	47	leading	lead	VERB
ecj-11500	94	48	to	to	ADP
ecj-11500	94	49	successful	successful	ADJ
ecj-11500	94	50	bleeding	bleeding	NOUN
ecj-11500	94	51	control.17,18	control.17,18	NOUN
ecj-11500	94	52	opting	opt	VERB
ecj-11500	94	53	for	for	ADP
ecj-11500	94	54	pcc3	pcc3	NOUN
ecj-11500	94	55	,	,	PUNCT
ecj-11500	94	56	which	which	PRON
ecj-11500	94	57	is	be	AUX
ecj-11500	94	58	generally	generally	ADV
ecj-11500	94	59	more	more	ADV
ecj-11500	94	60	economical	economical	ADJ
ecj-11500	94	61	than	than	ADP
ecj-11500	94	62	pcc4	pcc4	ADJ
ecj-11500	94	63	,	,	PUNCT
ecj-11500	94	64	as	as	SCONJ
ecj-11500	94	65	the	the	DET
ecj-11500	94	66	initial	initial	ADJ
ecj-11500	94	67	treatment	treatment	NOUN
ecj-11500	94	68	can	can	AUX
ecj-11500	94	69	be	be	AUX
ecj-11500	94	70	particularly	particularly	ADV
ecj-11500	94	71	advantageous	advantageous	ADJ
ecj-11500	94	72	in	in	ADP
ecj-11500	94	73	healthcare	healthcare	NOUN
ecj-11500	94	74	environments	environment	NOUN
ecj-11500	94	75	where	where	SCONJ
ecj-11500	94	76	cost	cost	NOUN
ecj-11500	94	77	-	-	PUNCT
ecj-11500	94	78	efficiency	efficiency	NOUN
ecj-11500	94	79	is	be	AUX
ecj-11500	94	80	crucial	crucial	ADJ
ecj-11500	94	81	.	.	PUNCT
ecj-11500	95	1	thromboelastometry	thromboelastometry	NOUN
ecj-11500	95	2	can	can	AUX
ecj-11500	95	3	serve	serve	VERB
ecj-11500	95	4	as	as	ADP
ecj-11500	95	5	a	a	DET
ecj-11500	95	6	rapid	rapid	ADJ
ecj-11500	95	7	and	and	CCONJ
ecj-11500	95	8	real	real	ADJ
ecj-11500	95	9	-	-	PUNCT
ecj-11500	95	10	time	time	NOUN
ecj-11500	95	11	diagnostic	diagnostic	ADJ
ecj-11500	95	12	mini	mini	ADJ
ecj-11500	95	13	review	review	NOUN
ecj-11500	95	14	[	[	X
ecj-11500	95	15	page	page	NOUN
ecj-11500	95	16	7	7	NUM
ecj-11500	95	17	]	]	PUNCT
ecj-11500	96	1	[	[	X
ecj-11500	96	2	emergency	emergency	NOUN
ecj-11500	96	3	care	care	NOUN
ecj-11500	96	4	journal	journal	NOUN
ecj-11500	96	5	2023	2023	NUM
ecj-11500	96	6	;	;	PUNCT
ecj-11500	96	7	19:11500	19:11500	NUM
ecj-11500	96	8	]	]	X
ecj-11500	96	9	non	non	ADJ
ecj-11500	96	10	-co	-co	PROPN
ecj-11500	96	11	mmerc	mmerc	PROPN
ecj-11500	96	12	ial	ial	PROPN
ecj-11500	96	13	us	us	PROPN
ecj-11500	96	14	e	e	NOUN
ecj-11500	96	15	o	o	NOUN
ecj-11500	96	16	nly	nly	ADV
ecj-11500	96	17	tool	tool	ADJ
ecj-11500	96	18	to	to	PART
ecj-11500	96	19	tailor	tailor	VERB
ecj-11500	96	20	the	the	DET
ecj-11500	96	21	treatment	treatment	NOUN
ecj-11500	96	22	approach	approach	NOUN
ecj-11500	96	23	,	,	PUNCT
ecj-11500	96	24	potentially	potentially	ADV
ecj-11500	96	25	enhancing	enhance	VERB
ecj-11500	96	26	patient	patient	ADJ
ecj-11500	96	27	outcomes	outcome	NOUN
ecj-11500	96	28	while	while	SCONJ
ecj-11500	96	29	reducing	reduce	VERB
ecj-11500	96	30	the	the	DET
ecj-11500	96	31	risk	risk	NOUN
ecj-11500	96	32	of	of	ADP
ecj-11500	96	33	adverse	adverse	ADJ
ecj-11500	96	34	events	event	NOUN
ecj-11500	96	35	.	.	PUNCT
ecj-11500	97	1	however	however	ADV
ecj-11500	97	2	,	,	PUNCT
ecj-11500	97	3	such	such	DET
ecj-11500	97	4	an	an	DET
ecj-11500	97	5	approach	approach	NOUN
ecj-11500	97	6	demands	demand	VERB
ecj-11500	97	7	rigorous	rigorous	ADJ
ecj-11500	97	8	monitoring	monitoring	NOUN
ecj-11500	97	9	and	and	CCONJ
ecj-11500	97	10	profound	profound	ADJ
ecj-11500	97	11	clinical	clinical	ADJ
ecj-11500	97	12	expertise	expertise	NOUN
ecj-11500	97	13	to	to	PART
ecj-11500	97	14	ascertain	ascertain	VERB
ecj-11500	97	15	the	the	DET
ecj-11500	97	16	appropriate	appropriate	ADJ
ecj-11500	97	17	use	use	NOUN
ecj-11500	97	18	of	of	ADP
ecj-11500	97	19	factor	factor	NOUN
ecj-11500	97	20	vii	vii	PROPN
ecj-11500	97	21	.	.	PUNCT
ecj-11500	98	1	additionally	additionally	ADV
ecj-11500	98	2	,	,	PUNCT
ecj-11500	98	3	the	the	DET
ecj-11500	98	4	inherent	inherent	ADJ
ecj-11500	98	5	risk	risk	NOUN
ecj-11500	98	6	of	of	ADP
ecj-11500	98	7	thromboembolic	thromboembolic	ADJ
ecj-11500	98	8	events	event	NOUN
ecj-11500	98	9	associated	associate	VERB
ecj-11500	98	10	with	with	ADP
ecj-11500	98	11	factor	factor	NOUN
ecj-11500	98	12	replacement	replacement	NOUN
ecj-11500	98	13	calls	call	VERB
ecj-11500	98	14	for	for	ADP
ecj-11500	98	15	meticulous	meticulous	ADJ
ecj-11500	98	16	consideration	consideration	NOUN
ecj-11500	98	17	and	and	CCONJ
ecj-11500	98	18	surveillance.9,10	surveillance.9,10	PROPN
ecj-11500	98	19	in	in	ADP
ecj-11500	98	20	summary	summary	NOUN
ecj-11500	98	21	,	,	PUNCT
ecj-11500	98	22	while	while	SCONJ
ecj-11500	98	23	the	the	DET
ecj-11500	98	24	proposed	propose	VERB
ecj-11500	98	25	strategy	strategy	NOUN
ecj-11500	98	26	of	of	ADP
ecj-11500	98	27	integrating	integrate	VERB
ecj-11500	98	28	pcc3	pcc3	NOUN
ecj-11500	98	29	with	with	ADP
ecj-11500	98	30	rotem	rotem	NOUN
ecj-11500	98	31	-	-	PUNCT
ecj-11500	98	32	guided	guide	VERB
ecj-11500	98	33	factor	factor	NOUN
ecj-11500	98	34	vii	vii	PROPN
ecj-11500	98	35	administration	administration	PROPN
ecj-11500	98	36	offers	offer	VERB
ecj-11500	98	37	potential	potential	ADJ
ecj-11500	98	38	benefits	benefit	NOUN
ecj-11500	98	39	in	in	ADP
ecj-11500	98	40	terms	term	NOUN
ecj-11500	98	41	of	of	ADP
ecj-11500	98	42	cost	cost	NOUN
ecj-11500	98	43	and	and	CCONJ
ecj-11500	98	44	personalized	personalized	ADJ
ecj-11500	98	45	treatment	treatment	NOUN
ecj-11500	98	46	,	,	PUNCT
ecj-11500	98	47	its	its	PRON
ecj-11500	98	48	full	full	ADJ
ecj-11500	98	49	efficacy	efficacy	NOUN
ecj-11500	98	50	and	and	CCONJ
ecj-11500	98	51	safety	safety	NOUN
ecj-11500	98	52	profile	profile	NOUN
ecj-11500	98	53	requires	require	VERB
ecj-11500	98	54	further	further	ADJ
ecj-11500	98	55	exploration	exploration	NOUN
ecj-11500	98	56	in	in	ADP
ecj-11500	98	57	broader	broad	ADJ
ecj-11500	98	58	clinical	clinical	ADJ
ecj-11500	98	59	settings	setting	NOUN
ecj-11500	98	60	.	.	PUNCT
ecj-11500	99	1	tranexamic	tranexamic	ADJ
ecj-11500	99	2	acid	acid	NOUN
ecj-11500	99	3	tranexamic	tranexamic	ADJ
ecj-11500	99	4	acid	acid	NOUN
ecj-11500	99	5	(	(	PUNCT
ecj-11500	99	6	txa	txa	PROPN
ecj-11500	99	7	)	)	PUNCT
ecj-11500	99	8	is	be	AUX
ecj-11500	99	9	an	an	DET
ecj-11500	99	10	anti	anti	ADJ
ecj-11500	99	11	-	-	ADJ
ecj-11500	99	12	fibrinolytic	fibrinolytic	ADJ
ecj-11500	99	13	agent	agent	NOUN
ecj-11500	99	14	that	that	PRON
ecj-11500	99	15	has	have	AUX
ecj-11500	99	16	been	be	AUX
ecj-11500	99	17	used	use	VERB
ecj-11500	99	18	to	to	PART
ecj-11500	99	19	reduce	reduce	VERB
ecj-11500	99	20	bleeding	bleed	VERB
ecj-11500	99	21	in	in	ADP
ecj-11500	99	22	various	various	ADJ
ecj-11500	99	23	clinical	clinical	ADJ
ecj-11500	99	24	scenarios	scenario	NOUN
ecj-11500	99	25	,	,	PUNCT
ecj-11500	99	26	including	include	VERB
ecj-11500	99	27	surgery	surgery	NOUN
ecj-11500	99	28	,	,	PUNCT
ecj-11500	99	29	trauma	trauma	NOUN
ecj-11500	99	30	,	,	PUNCT
ecj-11500	99	31	and	and	CCONJ
ecj-11500	99	32	menstruation	menstruation	NOUN
ecj-11500	99	33	.	.	PUNCT
ecj-11500	100	1	in	in	ADP
ecj-11500	100	2	the	the	DET
ecj-11500	100	3	context	context	NOUN
ecj-11500	100	4	of	of	ADP
ecj-11500	100	5	trauma	trauma	NOUN
ecj-11500	100	6	,	,	PUNCT
ecj-11500	100	7	the	the	DET
ecj-11500	100	8	benefits	benefit	NOUN
ecj-11500	100	9	of	of	ADP
ecj-11500	100	10	txa	txa	PROPN
ecj-11500	100	11	have	have	AUX
ecj-11500	100	12	been	be	AUX
ecj-11500	100	13	a	a	DET
ecj-11500	100	14	point	point	NOUN
ecj-11500	100	15	of	of	ADP
ecj-11500	100	16	debate	debate	NOUN
ecj-11500	100	17	.	.	PUNCT
ecj-11500	101	1	early	early	ADJ
ecj-11500	101	2	administration	administration	NOUN
ecj-11500	101	3	appears	appear	VERB
ecj-11500	101	4	to	to	PART
ecj-11500	101	5	enhance	enhance	VERB
ecj-11500	101	6	patient	patient	ADJ
ecj-11500	101	7	survival	survival	NOUN
ecj-11500	101	8	,	,	PUNCT
ecj-11500	101	9	but	but	CCONJ
ecj-11500	101	10	administering	administer	VERB
ecj-11500	101	11	txa	txa	NOUN
ecj-11500	101	12	after	after	ADP
ecj-11500	101	13	3	3	NUM
ecj-11500	101	14	hours	hour	NOUN
ecj-11500	101	15	post	post	ADJ
ecj-11500	101	16	-	-	NOUN
ecj-11500	101	17	admission	admission	NOUN
ecj-11500	101	18	might	might	AUX
ecj-11500	101	19	have	have	VERB
ecj-11500	101	20	detrimental	detrimental	ADJ
ecj-11500	101	21	effects	effect	NOUN
ecj-11500	101	22	.	.	PUNCT
ecj-11500	102	1	severe	severe	ADJ
ecj-11500	102	2	trauma	trauma	NOUN
ecj-11500	102	3	often	often	ADV
ecj-11500	102	4	induces	induce	VERB
ecj-11500	102	5	a	a	DET
ecj-11500	102	6	coagulopathic	coagulopathic	ADJ
ecj-11500	102	7	state	state	NOUN
ecj-11500	102	8	known	know	VERB
ecj-11500	102	9	as	as	ADP
ecj-11500	102	10	acute	acute	ADJ
ecj-11500	102	11	traumatic	traumatic	ADJ
ecj-11500	102	12	coagulopathy	coagulopathy	ADJ
ecj-11500	102	13	(	(	PUNCT
ecj-11500	102	14	atc	atc	NOUN
ecj-11500	102	15	)	)	PUNCT
ecj-11500	102	16	,	,	PUNCT
ecj-11500	102	17	characterized	characterize	VERB
ecj-11500	102	18	by	by	ADP
ecj-11500	102	19	increased	increase	VERB
ecj-11500	102	20	bleeding	bleeding	NOUN
ecj-11500	102	21	and	and	CCONJ
ecj-11500	102	22	resultant	resultant	VERB
ecj-11500	102	23	mortality	mortality	NOUN
ecj-11500	102	24	.	.	PUNCT
ecj-11500	103	1	hyperfibrinolysis	hyperfibrinolysis	NOUN
ecj-11500	103	2	is	be	AUX
ecj-11500	103	3	one	one	NUM
ecj-11500	103	4	mechanism	mechanism	NOUN
ecj-11500	103	5	contributing	contribute	VERB
ecj-11500	103	6	to	to	ADP
ecj-11500	103	7	the	the	DET
ecj-11500	103	8	observed	observed	ADJ
ecj-11500	103	9	phenotypes	phenotype	NOUN
ecj-11500	103	10	in	in	ADP
ecj-11500	103	11	the	the	DET
ecj-11500	103	12	early	early	ADJ
ecj-11500	103	13	stages	stage	NOUN
ecj-11500	103	14	of	of	ADP
ecj-11500	103	15	atc	atc	NOUN
ecj-11500	103	16	.	.	PUNCT
ecj-11500	104	1	txa	txa	PROPN
ecj-11500	104	2	acts	act	NOUN
ecj-11500	104	3	by	by	ADP
ecj-11500	104	4	binding	bind	VERB
ecj-11500	104	5	to	to	ADP
ecj-11500	104	6	plasminogen	plasminogen	NOUN
ecj-11500	104	7	,	,	PUNCT
ecj-11500	104	8	preventing	prevent	VERB
ecj-11500	104	9	its	its	PRON
ecj-11500	104	10	interaction	interaction	NOUN
ecj-11500	104	11	with	with	ADP
ecj-11500	104	12	fibrin	fibrin	NOUN
ecj-11500	104	13	.	.	PUNCT
ecj-11500	105	1	this	this	DET
ecj-11500	105	2	inhibition	inhibition	NOUN
ecj-11500	105	3	curtails	curtail	VERB
ecj-11500	105	4	the	the	DET
ecj-11500	105	5	activation	activation	NOUN
ecj-11500	105	6	of	of	ADP
ecj-11500	105	7	plasmin	plasmin	ADJ
ecj-11500	105	8	by	by	ADP
ecj-11500	105	9	tissue	tissue	NOUN
ecj-11500	105	10	-	-	PUNCT
ecj-11500	105	11	plasminogen	plasminogen	NOUN
ecj-11500	105	12	activator	activator	NOUN
ecj-11500	105	13	(	(	PUNCT
ecj-11500	105	14	t	t	PROPN
ecj-11500	105	15	-	-	PUNCT
ecj-11500	105	16	pa	pa	PROPN
ecj-11500	105	17	)	)	PUNCT
ecj-11500	105	18	,	,	PUNCT
ecj-11500	105	19	effectively	effectively	ADV
ecj-11500	105	20	lowering	lower	VERB
ecj-11500	105	21	plasminogen	plasminogen	NOUN
ecj-11500	105	22	concentration	concentration	NOUN
ecj-11500	105	23	.	.	PUNCT
ecj-11500	106	1	using	use	VERB
ecj-11500	106	2	excessive	excessive	ADJ
ecj-11500	106	3	t	t	PROPN
ecj-11500	106	4	-	-	PUNCT
ecj-11500	106	5	pa	pa	PROPN
ecj-11500	106	6	to	to	PART
ecj-11500	106	7	simulate	simulate	VERB
ecj-11500	106	8	atc	atc	ADJ
ecj-11500	106	9	bleeding	bleeding	NOUN
ecj-11500	106	10	phenotypes	phenotype	NOUN
ecj-11500	106	11	,	,	PUNCT
ecj-11500	106	12	researchers	researcher	NOUN
ecj-11500	106	13	found	find	VERB
ecj-11500	106	14	that	that	SCONJ
ecj-11500	106	15	txa	txa	NOUN
ecj-11500	106	16	is	be	AUX
ecj-11500	106	17	more	more	ADV
ecj-11500	106	18	beneficial	beneficial	ADJ
ecj-11500	106	19	than	than	ADP
ecj-11500	106	20	antiplasmin	antiplasmin	VERB
ecj-11500	106	21	treatment	treatment	NOUN
ecj-11500	106	22	when	when	SCONJ
ecj-11500	106	23	administered	administer	VERB
ecj-11500	106	24	early	early	ADV
ecj-11500	106	25	,	,	PUNCT
ecj-11500	106	26	whereas	whereas	SCONJ
ecj-11500	106	27	antiplasmin	antiplasmin	VERB
ecj-11500	106	28	proves	prove	VERB
ecj-11500	106	29	superior	superior	ADJ
ecj-11500	106	30	at	at	ADP
ecj-11500	106	31	later	later	ADJ
ecj-11500	106	32	treatment	treatment	NOUN
ecj-11500	106	33	times.19	times.19	NOUN
ecj-11500	106	34	regarding	regard	VERB
ecj-11500	106	35	gastrointestinal	gastrointestinal	ADJ
ecj-11500	106	36	bleeding	bleeding	NOUN
ecj-11500	106	37	,	,	PUNCT
ecj-11500	106	38	the	the	DET
ecj-11500	106	39	halt	halt	NOUN
ecj-11500	106	40	-	-	PUNCT
ecj-11500	106	41	it	it	PRON
ecj-11500	106	42	trial	trial	NOUN
ecj-11500	106	43	assessed	assess	VERB
ecj-11500	106	44	the	the	DET
ecj-11500	106	45	efficacy	efficacy	NOUN
ecj-11500	106	46	of	of	ADP
ecj-11500	106	47	txa	txa	PROPN
ecj-11500	106	48	.	.	PUNCT
ecj-11500	107	1	while	while	SCONJ
ecj-11500	107	2	the	the	DET
ecj-11500	107	3	study	study	NOUN
ecj-11500	107	4	noted	note	VERB
ecj-11500	107	5	a	a	DET
ecj-11500	107	6	reduction	reduction	NOUN
ecj-11500	107	7	in	in	ADP
ecj-11500	107	8	re	re	ADJ
ecj-11500	107	9	-	-	ADJ
ecj-11500	107	10	bleeding	bleeding	ADJ
ecj-11500	107	11	events	event	NOUN
ecj-11500	107	12	,	,	PUNCT
ecj-11500	107	13	there	there	PRON
ecj-11500	107	14	was	be	VERB
ecj-11500	107	15	no	no	DET
ecj-11500	107	16	significant	significant	ADJ
ecj-11500	107	17	reduction	reduction	NOUN
ecj-11500	107	18	in	in	ADP
ecj-11500	107	19	mortality	mortality	NOUN
ecj-11500	107	20	.	.	PUNCT
ecj-11500	108	1	this	this	PRON
ecj-11500	108	2	suggests	suggest	VERB
ecj-11500	108	3	that	that	SCONJ
ecj-11500	108	4	txa	txa	PROPN
ecj-11500	108	5	might	might	AUX
ecj-11500	108	6	be	be	AUX
ecj-11500	108	7	advantageous	advantageous	ADJ
ecj-11500	108	8	in	in	ADP
ecj-11500	108	9	specific	specific	ADJ
ecj-11500	108	10	scenarios	scenario	NOUN
ecj-11500	108	11	or	or	CCONJ
ecj-11500	108	12	patient	patient	ADJ
ecj-11500	108	13	populations	population	NOUN
ecj-11500	108	14	,	,	PUNCT
ecj-11500	108	15	but	but	CCONJ
ecj-11500	108	16	its	its	PRON
ecj-11500	108	17	broad	broad	ADJ
ecj-11500	108	18	application	application	NOUN
ecj-11500	108	19	for	for	ADP
ecj-11500	108	20	gastrointestinal	gastrointestinal	ADJ
ecj-11500	108	21	bleeding	bleeding	NOUN
ecj-11500	108	22	warrants	warrant	NOUN
ecj-11500	108	23	more	more	ADJ
ecj-11500	108	24	in	in	ADP
ecj-11500	108	25	-	-	PUNCT
ecj-11500	108	26	depth	depth	NOUN
ecj-11500	108	27	analysis.20	analysis.20	NOUN
ecj-11500	108	28	in	in	ADP
ecj-11500	108	29	conclusion	conclusion	NOUN
ecj-11500	108	30	,	,	PUNCT
ecj-11500	108	31	txa	txa	PROPN
ecj-11500	108	32	has	have	VERB
ecj-11500	108	33	a	a	DET
ecj-11500	108	34	pivotal	pivotal	ADJ
ecj-11500	108	35	role	role	NOUN
ecj-11500	108	36	in	in	ADP
ecj-11500	108	37	counteracting	counteract	VERB
ecj-11500	108	38	hyperfibrinolysis	hyperfibrinolysis	NOUN
ecj-11500	108	39	,	,	PUNCT
ecj-11500	108	40	particularly	particularly	ADV
ecj-11500	108	41	when	when	SCONJ
ecj-11500	108	42	given	give	VERB
ecj-11500	108	43	promptly	promptly	ADV
ecj-11500	108	44	.	.	PUNCT
ecj-11500	109	1	however	however	ADV
ecj-11500	109	2	,	,	PUNCT
ecj-11500	109	3	its	its	PRON
ecj-11500	109	4	potency	potency	NOUN
ecj-11500	109	5	wanes	wane	VERB
ecj-11500	109	6	as	as	ADP
ecj-11500	109	7	time	time	NOUN
ecj-11500	109	8	progresses	progress	NOUN
ecj-11500	109	9	,	,	PUNCT
ecj-11500	109	10	emphasizing	emphasize	VERB
ecj-11500	109	11	the	the	DET
ecj-11500	109	12	need	need	NOUN
ecj-11500	109	13	for	for	ADP
ecj-11500	109	14	alternative	alternative	ADJ
ecj-11500	109	15	treatments	treatment	NOUN
ecj-11500	109	16	in	in	ADP
ecj-11500	109	17	trauma	trauma	NOUN
ecj-11500	109	18	’s	’s	PART
ecj-11500	109	19	later	later	ADJ
ecj-11500	109	20	stages	stage	NOUN
ecj-11500	109	21	.	.	PUNCT
ecj-11500	110	1	fibrinogen	fibrinogen	NOUN
ecj-11500	110	2	in	in	ADP
ecj-11500	110	3	trauma	trauma	NOUN
ecj-11500	110	4	fibrinogen	fibrinogen	NOUN
ecj-11500	110	5	is	be	AUX
ecj-11500	110	6	a	a	DET
ecj-11500	110	7	crucial	crucial	ADJ
ecj-11500	110	8	component	component	NOUN
ecj-11500	110	9	in	in	ADP
ecj-11500	110	10	the	the	DET
ecj-11500	110	11	coagulation	coagulation	NOUN
ecj-11500	110	12	cascade	cascade	NOUN
ecj-11500	110	13	and	and	CCONJ
ecj-11500	110	14	plays	play	VERB
ecj-11500	110	15	a	a	DET
ecj-11500	110	16	significant	significant	ADJ
ecj-11500	110	17	role	role	NOUN
ecj-11500	110	18	in	in	ADP
ecj-11500	110	19	the	the	DET
ecj-11500	110	20	formation	formation	NOUN
ecj-11500	110	21	of	of	ADP
ecj-11500	110	22	a	a	DET
ecj-11500	110	23	stable	stable	ADJ
ecj-11500	110	24	clot	clot	NOUN
ecj-11500	110	25	.	.	PUNCT
ecj-11500	111	1	in	in	ADP
ecj-11500	111	2	trauma	trauma	NOUN
ecj-11500	111	3	situations	situation	NOUN
ecj-11500	111	4	,	,	PUNCT
ecj-11500	111	5	fibrinogen	fibrinogen	NOUN
ecj-11500	111	6	levels	level	NOUN
ecj-11500	111	7	tend	tend	VERB
ecj-11500	111	8	to	to	PART
ecj-11500	111	9	deteriorate	deteriorate	VERB
ecj-11500	111	10	faster	fast	ADV
ecj-11500	111	11	than	than	ADP
ecj-11500	111	12	other	other	ADJ
ecj-11500	111	13	coagulation	coagulation	NOUN
ecj-11500	111	14	factors	factor	NOUN
ecj-11500	111	15	,	,	PUNCT
ecj-11500	111	16	which	which	PRON
ecj-11500	111	17	can	can	AUX
ecj-11500	111	18	lead	lead	VERB
ecj-11500	111	19	to	to	ADP
ecj-11500	111	20	severe	severe	ADJ
ecj-11500	111	21	bleeding	bleeding	NOUN
ecj-11500	111	22	and	and	CCONJ
ecj-11500	111	23	increased	increase	VERB
ecj-11500	111	24	mortality	mortality	NOUN
ecj-11500	111	25	rates	rate	NOUN
ecj-11500	111	26	.	.	PUNCT
ecj-11500	112	1	therefore	therefore	ADV
ecj-11500	112	2	,	,	PUNCT
ecj-11500	112	3	aggressive	aggressive	ADJ
ecj-11500	112	4	supplementation	supplementation	NOUN
ecj-11500	112	5	of	of	ADP
ecj-11500	112	6	fibrinogen	fibrinogen	NOUN
ecj-11500	112	7	is	be	AUX
ecj-11500	112	8	often	often	ADV
ecj-11500	112	9	necessary	necessary	ADJ
ecj-11500	112	10	in	in	ADP
ecj-11500	112	11	these	these	DET
ecj-11500	112	12	cases	case	NOUN
ecj-11500	112	13	.	.	PUNCT
ecj-11500	113	1	fibrinogen	fibrinogen	NOUN
ecj-11500	113	2	can	can	AUX
ecj-11500	113	3	be	be	AUX
ecj-11500	113	4	supplemented	supplement	VERB
ecj-11500	113	5	with	with	ADP
ecj-11500	113	6	fresh	fresh	ADJ
ecj-11500	113	7	-	-	PUNCT
ecj-11500	113	8	frozen	frozen	ADJ
ecj-11500	113	9	plasma	plasma	NOUN
ecj-11500	113	10	(	(	PUNCT
ecj-11500	113	11	ffp	ffp	PROPN
ecj-11500	113	12	)	)	PUNCT
ecj-11500	113	13	,	,	PUNCT
ecj-11500	113	14	cryoprecipitate	cryoprecipitate	VERB
ecj-11500	113	15	,	,	PUNCT
ecj-11500	113	16	or	or	CCONJ
ecj-11500	113	17	fibrinogen	fibrinogen	NOUN
ecj-11500	113	18	concentrate	concentrate	NOUN
ecj-11500	113	19	(	(	PUNCT
ecj-11500	113	20	fc	fc	INTJ
ecj-11500	113	21	)	)	PUNCT
ecj-11500	113	22	.	.	PUNCT
ecj-11500	114	1	fc	fc	PROPN
ecj-11500	114	2	has	have	VERB
ecj-11500	114	3	several	several	ADJ
ecj-11500	114	4	advantages	advantage	NOUN
ecj-11500	114	5	over	over	ADP
ecj-11500	114	6	these	these	DET
ecj-11500	114	7	alternatives	alternative	NOUN
ecj-11500	114	8	,	,	PUNCT
ecj-11500	114	9	including	include	VERB
ecj-11500	114	10	the	the	DET
ecj-11500	114	11	fact	fact	NOUN
ecj-11500	114	12	that	that	SCONJ
ecj-11500	114	13	it	it	PRON
ecj-11500	114	14	does	do	AUX
ecj-11500	114	15	not	not	PART
ecj-11500	114	16	require	require	VERB
ecj-11500	114	17	a	a	DET
ecj-11500	114	18	thawing	thaw	VERB
ecj-11500	114	19	process	process	NOUN
ecj-11500	114	20	or	or	CCONJ
ecj-11500	114	21	abo	abo	VERB
ecj-11500	114	22	compatibility	compatibility	NOUN
ecj-11500	114	23	confirmation.1	confirmation.1	NOUN
ecj-11500	114	24	furthermore	furthermore	ADV
ecj-11500	114	25	,	,	PUNCT
ecj-11500	114	26	fc	fc	PROPN
ecj-11500	114	27	may	may	AUX
ecj-11500	114	28	increase	increase	VERB
ecj-11500	114	29	plasma	plasma	NOUN
ecj-11500	114	30	fibrinogen	fibrinogen	NOUN
ecj-11500	114	31	levels	level	NOUN
ecj-11500	114	32	more	more	ADV
ecj-11500	114	33	rapidly	rapidly	ADV
ecj-11500	114	34	than	than	ADP
ecj-11500	114	35	ffp	ffp	PROPN
ecj-11500	114	36	or	or	CCONJ
ecj-11500	114	37	cryoprecipitate1	cryoprecipitate1	NOUN
ecj-11500	114	38	and	and	CCONJ
ecj-11500	114	39	reduce	reduce	VERB
ecj-11500	114	40	transfusion	transfusion	NOUN
ecj-11500	114	41	volume	volume	NOUN
ecj-11500	114	42	and	and	CCONJ
ecj-11500	114	43	the	the	DET
ecj-11500	114	44	risk	risk	NOUN
ecj-11500	114	45	of	of	ADP
ecj-11500	114	46	immunogenic	immunogenic	ADJ
ecj-11500	114	47	or	or	CCONJ
ecj-11500	114	48	infectious	infectious	ADJ
ecj-11500	114	49	complications	complication	NOUN
ecj-11500	114	50	.	.	PUNCT
ecj-11500	115	1	these	these	DET
ecj-11500	115	2	features	feature	NOUN
ecj-11500	115	3	make	make	VERB
ecj-11500	115	4	fc	fc	PROPN
ecj-11500	115	5	a	a	DET
ecj-11500	115	6	promising	promising	ADJ
ecj-11500	115	7	option	option	NOUN
ecj-11500	115	8	for	for	ADP
ecj-11500	115	9	the	the	DET
ecj-11500	115	10	management	management	NOUN
ecj-11500	115	11	of	of	ADP
ecj-11500	115	12	hemorrhage	hemorrhage	NOUN
ecj-11500	115	13	in	in	ADP
ecj-11500	115	14	trauma	trauma	NOUN
ecj-11500	115	15	patients	patient	NOUN
ecj-11500	115	16	.	.	PUNCT
ecj-11500	116	1	however	however	ADV
ecj-11500	116	2	,	,	PUNCT
ecj-11500	116	3	the	the	DET
ecj-11500	116	4	use	use	NOUN
ecj-11500	116	5	of	of	ADP
ecj-11500	116	6	fc	fc	PROPN
ecj-11500	116	7	in	in	ADP
ecj-11500	116	8	trauma	trauma	NOUN
ecj-11500	116	9	settings	setting	NOUN
ecj-11500	116	10	has	have	AUX
ecj-11500	116	11	been	be	AUX
ecj-11500	116	12	a	a	DET
ecj-11500	116	13	subject	subject	NOUN
ecj-11500	116	14	of	of	ADP
ecj-11500	116	15	debate	debate	NOUN
ecj-11500	116	16	.	.	PUNCT
ecj-11500	117	1	while	while	SCONJ
ecj-11500	117	2	some	some	DET
ecj-11500	117	3	studies	study	NOUN
ecj-11500	117	4	have	have	AUX
ecj-11500	117	5	shown	show	VERB
ecj-11500	117	6	that	that	SCONJ
ecj-11500	117	7	fc	fc	PROPN
ecj-11500	117	8	can	can	AUX
ecj-11500	117	9	rapidly	rapidly	ADV
ecj-11500	117	10	supplement	supplement	VERB
ecj-11500	117	11	fibrinogen	fibrinogen	NOUN
ecj-11500	117	12	levels	level	NOUN
ecj-11500	117	13	and	and	CCONJ
ecj-11500	117	14	reduce	reduce	VERB
ecj-11500	117	15	the	the	DET
ecj-11500	117	16	need	need	NOUN
ecj-11500	117	17	for	for	ADP
ecj-11500	117	18	massive	massive	ADJ
ecj-11500	117	19	transfusion	transfusion	NOUN
ecj-11500	117	20	,	,	PUNCT
ecj-11500	117	21	others	other	NOUN
ecj-11500	117	22	have	have	AUX
ecj-11500	117	23	found	find	VERB
ecj-11500	117	24	that	that	SCONJ
ecj-11500	117	25	fc	fc	PROPN
ecj-11500	117	26	did	do	AUX
ecj-11500	117	27	not	not	PART
ecj-11500	117	28	significantly	significantly	ADV
ecj-11500	117	29	improve	improve	VERB
ecj-11500	117	30	mortality	mortality	NOUN
ecj-11500	117	31	rates	rate	NOUN
ecj-11500	117	32	or	or	CCONJ
ecj-11500	117	33	reduce	reduce	VERB
ecj-11500	117	34	transfusion	transfusion	NOUN
ecj-11500	117	35	requirements	requirement	NOUN
ecj-11500	117	36	in	in	ADP
ecj-11500	117	37	trauma	trauma	NOUN
ecj-11500	117	38	-	-	PUNCT
ecj-11500	117	39	related	relate	VERB
ecj-11500	117	40	randomized	randomize	VERB
ecj-11500	117	41	controlled	control	VERB
ecj-11500	117	42	trials	trial	NOUN
ecj-11500	117	43	(	(	PUNCT
ecj-11500	117	44	rcts	rct	NOUN
ecj-11500	117	45	)	)	PUNCT
ecj-11500	117	46	.	.	PUNCT
ecj-11500	118	1	these	these	DET
ecj-11500	118	2	conflicting	conflicting	ADJ
ecj-11500	118	3	results	result	NOUN
ecj-11500	118	4	highlight	highlight	VERB
ecj-11500	118	5	the	the	DET
ecj-11500	118	6	need	need	NOUN
ecj-11500	118	7	for	for	ADP
ecj-11500	118	8	further	further	ADJ
ecj-11500	118	9	research	research	NOUN
ecj-11500	118	10	to	to	PART
ecj-11500	118	11	determine	determine	VERB
ecj-11500	118	12	the	the	DET
ecj-11500	118	13	optimal	optimal	ADJ
ecj-11500	118	14	use	use	NOUN
ecj-11500	118	15	of	of	ADP
ecj-11500	118	16	fc	fc	PROPN
ecj-11500	118	17	in	in	ADP
ecj-11500	118	18	trauma	trauma	NOUN
ecj-11500	118	19	settings	setting	NOUN
ecj-11500	118	20	.	.	PUNCT
ecj-11500	119	1	in	in	ADP
ecj-11500	119	2	a	a	DET
ecj-11500	119	3	systematic	systematic	ADJ
ecj-11500	119	4	review	review	NOUN
ecj-11500	119	5	and	and	CCONJ
ecj-11500	119	6	metaanalysis	metaanalysis	NOUN
ecj-11500	119	7	,	,	PUNCT
ecj-11500	119	8	it	it	PRON
ecj-11500	119	9	was	be	AUX
ecj-11500	119	10	found	find	VERB
ecj-11500	119	11	that	that	SCONJ
ecj-11500	119	12	fc	fc	PROPN
ecj-11500	119	13	did	do	AUX
ecj-11500	119	14	not	not	PART
ecj-11500	119	15	significantly	significantly	ADV
ecj-11500	119	16	decrease	decrease	VERB
ecj-11500	119	17	in	in	ADP
ecj-11500	119	18	-	-	PUNCT
ecj-11500	119	19	hospital	hospital	NOUN
ecj-11500	119	20	mortality	mortality	NOUN
ecj-11500	119	21	or	or	CCONJ
ecj-11500	119	22	the	the	DET
ecj-11500	119	23	amount	amount	NOUN
ecj-11500	119	24	of	of	ADP
ecj-11500	119	25	transfusion	transfusion	NOUN
ecj-11500	119	26	.	.	PUNCT
ecj-11500	120	1	however	however	ADV
ecj-11500	120	2	,	,	PUNCT
ecj-11500	120	3	fc	fc	PROPN
ecj-11500	120	4	may	may	AUX
ecj-11500	120	5	result	result	VERB
ecj-11500	120	6	in	in	ADP
ecj-11500	120	7	little	little	ADJ
ecj-11500	120	8	to	to	PART
ecj-11500	120	9	no	no	DET
ecj-11500	120	10	difference	difference	NOUN
ecj-11500	120	11	in	in	ADP
ecj-11500	120	12	thrombotic	thrombotic	ADJ
ecj-11500	120	13	events	event	NOUN
ecj-11500	120	14	and	and	CCONJ
ecj-11500	120	15	a	a	DET
ecj-11500	120	16	slight	slight	ADJ
ecj-11500	120	17	reduction	reduction	NOUN
ecj-11500	120	18	in	in	ADP
ecj-11500	120	19	the	the	DET
ecj-11500	120	20	risk	risk	NOUN
ecj-11500	120	21	of	of	ADP
ecj-11500	120	22	multiple	multiple	ADJ
ecj-11500	120	23	organ	organ	NOUN
ecj-11500	120	24	failure	failure	NOUN
ecj-11500	120	25	.	.	PUNCT
ecj-11500	121	1	it	it	PRON
ecj-11500	121	2	is	be	AUX
ecj-11500	121	3	important	important	ADJ
ecj-11500	121	4	to	to	PART
ecj-11500	121	5	note	note	VERB
ecj-11500	121	6	that	that	SCONJ
ecj-11500	121	7	due	due	ADP
ecj-11500	121	8	to	to	ADP
ecj-11500	121	9	the	the	DET
ecj-11500	121	10	unbalanced	unbalanced	ADJ
ecj-11500	121	11	severity	severity	NOUN
ecj-11500	121	12	of	of	ADP
ecj-11500	121	13	the	the	DET
ecj-11500	121	14	patient	patient	ADJ
ecj-11500	121	15	population	population	NOUN
ecj-11500	121	16	,	,	PUNCT
ecj-11500	121	17	high	high	ADJ
ecj-11500	121	18	levels	level	NOUN
ecj-11500	121	19	of	of	ADP
ecj-11500	121	20	heterogeneity	heterogeneity	NOUN
ecj-11500	121	21	,	,	PUNCT
ecj-11500	121	22	and	and	CCONJ
ecj-11500	121	23	risk	risk	NOUN
ecj-11500	121	24	of	of	ADP
ecj-11500	121	25	bias	bias	NOUN
ecj-11500	121	26	,	,	PUNCT
ecj-11500	121	27	these	these	DET
ecj-11500	121	28	results	result	NOUN
ecj-11500	121	29	should	should	AUX
ecj-11500	121	30	be	be	AUX
ecj-11500	121	31	interpreted	interpret	VERB
ecj-11500	121	32	cautiously	cautiously	ADV
ecj-11500	121	33	.	.	PUNCT
ecj-11500	122	1	in	in	ADP
ecj-11500	122	2	conclusion	conclusion	NOUN
ecj-11500	122	3	,	,	PUNCT
ecj-11500	122	4	while	while	SCONJ
ecj-11500	122	5	fc	fc	PROPN
ecj-11500	122	6	has	have	VERB
ecj-11500	122	7	potential	potential	ADJ
ecj-11500	122	8	benefits	benefit	NOUN
ecj-11500	122	9	in	in	ADP
ecj-11500	122	10	managing	manage	VERB
ecj-11500	122	11	hemorrhage	hemorrhage	NOUN
ecj-11500	122	12	in	in	ADP
ecj-11500	122	13	trauma	trauma	NOUN
ecj-11500	122	14	patients	patient	NOUN
ecj-11500	122	15	,	,	PUNCT
ecj-11500	122	16	more	more	ADJ
ecj-11500	122	17	research	research	NOUN
ecj-11500	122	18	is	be	AUX
ecj-11500	122	19	needed	need	VERB
ecj-11500	122	20	to	to	PART
ecj-11500	122	21	determine	determine	VERB
ecj-11500	122	22	its	its	PRON
ecj-11500	122	23	optimal	optimal	ADJ
ecj-11500	122	24	use	use	NOUN
ecj-11500	122	25	.	.	PUNCT
ecj-11500	123	1	the	the	DET
ecj-11500	123	2	current	current	ADJ
ecj-11500	123	3	evidence	evidence	NOUN
ecj-11500	123	4	suggests	suggest	VERB
ecj-11500	123	5	that	that	SCONJ
ecj-11500	123	6	fc	fc	PROPN
ecj-11500	123	7	may	may	AUX
ecj-11500	123	8	not	not	PART
ecj-11500	123	9	significantly	significantly	ADV
ecj-11500	123	10	reduce	reduce	VERB
ecj-11500	123	11	in	in	ADP
ecj-11500	123	12	-	-	PUNCT
ecj-11500	123	13	hospital	hospital	NOUN
ecj-11500	123	14	mortality	mortality	NOUN
ecj-11500	123	15	or	or	CCONJ
ecj-11500	123	16	the	the	DET
ecj-11500	123	17	need	need	NOUN
ecj-11500	123	18	for	for	ADP
ecj-11500	123	19	transfusion	transfusion	NOUN
ecj-11500	123	20	,	,	PUNCT
ecj-11500	123	21	but	but	CCONJ
ecj-11500	123	22	it	it	PRON
ecj-11500	123	23	may	may	AUX
ecj-11500	123	24	have	have	VERB
ecj-11500	123	25	a	a	DET
ecj-11500	123	26	slight	slight	ADJ
ecj-11500	123	27	beneficial	beneficial	ADJ
ecj-11500	123	28	effect	effect	NOUN
ecj-11500	123	29	on	on	ADP
ecj-11500	123	30	reducing	reduce	VERB
ecj-11500	123	31	the	the	DET
ecj-11500	123	32	risk	risk	NOUN
ecj-11500	123	33	of	of	ADP
ecj-11500	123	34	multiple	multiple	ADJ
ecj-11500	123	35	organ	organ	NOUN
ecj-11500	123	36	failure.21	failure.21	PROPN
ecj-11500	123	37	thromboelastometry	thromboelastometry	NOUN
ecj-11500	123	38	and	and	CCONJ
ecj-11500	123	39	thromboelastography	thromboelastography	NOUN
ecj-11500	123	40	thromboelastometry	thromboelastometry	PROPN
ecj-11500	123	41	(	(	PUNCT
ecj-11500	123	42	rotem	rotem	PROPN
ecj-11500	123	43	)	)	PUNCT
ecj-11500	123	44	and	and	CCONJ
ecj-11500	123	45	thromboelastography	thromboelastography	NOUN
ecj-11500	123	46	(	(	PUNCT
ecj-11500	123	47	teg	teg	NOUN
ecj-11500	123	48	)	)	PUNCT
ecj-11500	123	49	are	be	AUX
ecj-11500	123	50	point	point	NOUN
ecj-11500	123	51	-	-	PUNCT
ecj-11500	123	52	of	of	ADP
ecj-11500	123	53	-	-	PUNCT
ecj-11500	123	54	care	care	NOUN
ecj-11500	123	55	coagulation	coagulation	NOUN
ecj-11500	123	56	tests	test	NOUN
ecj-11500	123	57	that	that	PRON
ecj-11500	123	58	provide	provide	VERB
ecj-11500	123	59	comprehensive	comprehensive	ADJ
ecj-11500	123	60	information	information	NOUN
ecj-11500	123	61	about	about	ADP
ecj-11500	123	62	the	the	DET
ecj-11500	123	63	coagulation	coagulation	NOUN
ecj-11500	123	64	process	process	NOUN
ecj-11500	123	65	,	,	PUNCT
ecj-11500	123	66	from	from	SCONJ
ecj-11500	123	67	clot	clot	NOUN
ecj-11500	123	68	formation	formation	NOUN
ecj-11500	123	69	to	to	ADP
ecj-11500	123	70	fibrinolysis.22	fibrinolysis.22	NOUN
ecj-11500	123	71	-	-	PUNCT
ecj-11500	123	72	24	24	NUM
ecj-11500	123	73	both	both	DET
ecj-11500	123	74	methods	method	NOUN
ecj-11500	123	75	are	be	AUX
ecj-11500	123	76	established	establish	VERB
ecj-11500	123	77	in	in	ADP
ecj-11500	123	78	many	many	ADJ
ecj-11500	123	79	anesthesiologic	anesthesiologic	ADJ
ecj-11500	123	80	departments	department	NOUN
ecj-11500	123	81	for	for	ADP
ecj-11500	123	82	guided	guide	VERB
ecj-11500	123	83	hemostatic	hemostatic	ADJ
ecj-11500	123	84	treatment.24	treatment.24	NOUN
ecj-11500	123	85	rotem	rotem	NOUN
ecj-11500	123	86	and	and	CCONJ
ecj-11500	123	87	teg	teg	NOUN
ecj-11500	123	88	are	be	AUX
ecj-11500	123	89	similar	similar	ADJ
ecj-11500	123	90	in	in	ADP
ecj-11500	123	91	their	their	PRON
ecj-11500	123	92	basic	basic	ADJ
ecj-11500	123	93	principles	principle	NOUN
ecj-11500	123	94	,	,	PUNCT
ecj-11500	123	95	but	but	CCONJ
ecj-11500	123	96	there	there	PRON
ecj-11500	123	97	are	be	VERB
ecj-11500	123	98	some	some	DET
ecj-11500	123	99	differences	difference	NOUN
ecj-11500	123	100	in	in	ADP
ecj-11500	123	101	their	their	PRON
ecj-11500	123	102	technical	technical	ADJ
ecj-11500	123	103	execution	execution	NOUN
ecj-11500	123	104	and	and	CCONJ
ecj-11500	123	105	interpretation	interpretation	NOUN
ecj-11500	123	106	of	of	ADP
ecj-11500	123	107	results	result	NOUN
ecj-11500	123	108	.	.	PUNCT
ecj-11500	124	1	both	both	DET
ecj-11500	124	2	methods	method	NOUN
ecj-11500	124	3	measure	measure	VERB
ecj-11500	124	4	the	the	DET
ecj-11500	124	5	viscoelastic	viscoelastic	ADJ
ecj-11500	124	6	properties	property	NOUN
ecj-11500	124	7	of	of	ADP
ecj-11500	124	8	clot	clot	NOUN
ecj-11500	124	9	formation	formation	NOUN
ecj-11500	124	10	in	in	ADP
ecj-11500	124	11	whole	whole	ADJ
ecj-11500	124	12	blood	blood	NOUN
ecj-11500	124	13	,	,	PUNCT
ecj-11500	124	14	providing	provide	VERB
ecj-11500	124	15	a	a	DET
ecj-11500	124	16	dynamic	dynamic	ADJ
ecj-11500	124	17	assessment	assessment	NOUN
ecj-11500	124	18	of	of	ADP
ecj-11500	124	19	clot	clot	NOUN
ecj-11500	124	20	strength	strength	NOUN
ecj-11500	124	21	and	and	CCONJ
ecj-11500	124	22	stability.24	stability.24	PROPN
ecj-11500	124	23	rotem	rotem	PROPN
ecj-11500	124	24	has	have	AUX
ecj-11500	124	25	been	be	AUX
ecj-11500	124	26	shown	show	VERB
ecj-11500	124	27	to	to	PART
ecj-11500	124	28	be	be	AUX
ecj-11500	124	29	sensitive	sensitive	ADJ
ecj-11500	124	30	to	to	ADP
ecj-11500	124	31	subtle	subtle	ADJ
ecj-11500	124	32	changes	change	NOUN
ecj-11500	124	33	in	in	ADP
ecj-11500	124	34	coagulation	coagulation	NOUN
ecj-11500	124	35	,	,	PUNCT
ecj-11500	124	36	making	make	VERB
ecj-11500	124	37	it	it	PRON
ecj-11500	124	38	a	a	DET
ecj-11500	124	39	valuable	valuable	ADJ
ecj-11500	124	40	tool	tool	NOUN
ecj-11500	124	41	in	in	ADP
ecj-11500	124	42	the	the	DET
ecj-11500	124	43	management	management	NOUN
ecj-11500	124	44	of	of	ADP
ecj-11500	124	45	conditions	condition	NOUN
ecj-11500	124	46	such	such	ADJ
ecj-11500	124	47	as	as	ADP
ecj-11500	124	48	snakebite	snakebite	NOUN
ecj-11500	124	49	-	-	PUNCT
ecj-11500	124	50	induced	induce	VERB
ecj-11500	124	51	coagulopathy	coagulopathy	ADJ
ecj-11500	124	52	and	and	CCONJ
ecj-11500	124	53	acute	acute	ADJ
ecj-11500	124	54	ischemic	ischemic	ADJ
ecj-11500	124	55	stroke.23	stroke.23	VERB
ecj-11500	124	56	a	a	DET
ecj-11500	124	57	study	study	NOUN
ecj-11500	124	58	on	on	ADP
ecj-11500	124	59	hump	hump	NOUN
ecj-11500	124	60	-	-	PUNCT
ecj-11500	124	61	nosed	nosed	NOUN
ecj-11500	124	62	viper	viper	NOUN
ecj-11500	124	63	bites	bite	NOUN
ecj-11500	124	64	found	find	VERB
ecj-11500	124	65	that	that	SCONJ
ecj-11500	124	66	rotem	rotem	NOUN
ecj-11500	124	67	parameters	parameter	NOUN
ecj-11500	124	68	were	be	AUX
ecj-11500	124	69	more	more	ADV
ecj-11500	124	70	sensitive	sensitive	ADJ
ecj-11500	124	71	to	to	ADP
ecj-11500	124	72	subtle	subtle	ADJ
ecj-11500	124	73	changes	change	NOUN
ecj-11500	124	74	in	in	ADP
ecj-11500	124	75	coagulation	coagulation	NOUN
ecj-11500	124	76	compared	compare	VERB
ecj-11500	124	77	to	to	ADP
ecj-11500	124	78	standard	standard	ADJ
ecj-11500	124	79	diagnostic	diagnostic	ADJ
ecj-11500	124	80	tests.22	tests.22	NOUN
ecj-11500	124	81	similarly	similarly	ADV
ecj-11500	124	82	,	,	PUNCT
ecj-11500	124	83	a	a	DET
ecj-11500	124	84	pilot	pilot	NOUN
ecj-11500	124	85	study	study	NOUN
ecj-11500	124	86	on	on	ADP
ecj-11500	124	87	acute	acute	ADJ
ecj-11500	124	88	ischemic	ischemic	ADJ
ecj-11500	124	89	stroke	stroke	NOUN
ecj-11500	124	90	found	find	VERB
ecj-11500	124	91	a	a	DET
ecj-11500	124	92	correlation	correlation	NOUN
ecj-11500	124	93	between	between	ADP
ecj-11500	124	94	in	in	ADP
ecj-11500	124	95	vitro	vitro	X
ecj-11500	124	96	fibrinolysis	fibrinolysis	NOUN
ecj-11500	124	97	patterns	pattern	NOUN
ecj-11500	124	98	determined	determine	VERB
ecj-11500	124	99	using	use	VERB
ecj-11500	124	100	rotem	rotem	NOUN
ecj-11500	124	101	and	and	CCONJ
ecj-11500	124	102	early	early	ADJ
ecj-11500	124	103	clinical	clinical	ADJ
ecj-11500	124	104	outcomes.23	outcomes.23	NOUN
ecj-11500	124	105	on	on	ADP
ecj-11500	124	106	the	the	DET
ecj-11500	124	107	other	other	ADJ
ecj-11500	124	108	hand	hand	NOUN
ecj-11500	124	109	,	,	PUNCT
ecj-11500	124	110	teg	teg	PROPN
ecj-11500	124	111	is	be	AUX
ecj-11500	124	112	gaining	gain	VERB
ecj-11500	124	113	prominence	prominence	NOUN
ecj-11500	124	114	in	in	ADP
ecj-11500	124	115	various	various	ADJ
ecj-11500	124	116	clinical	clinical	ADJ
ecj-11500	124	117	settings	setting	NOUN
ecj-11500	124	118	,	,	PUNCT
ecj-11500	124	119	particularly	particularly	ADV
ecj-11500	124	120	in	in	ADP
ecj-11500	124	121	cardiac	cardiac	ADJ
ecj-11500	124	122	surgery	surgery	NOUN
ecj-11500	124	123	,	,	PUNCT
ecj-11500	124	124	trauma	trauma	NOUN
ecj-11500	124	125	,	,	PUNCT
ecj-11500	124	126	and	and	CCONJ
ecj-11500	124	127	liver	liver	NOUN
ecj-11500	124	128	disease	disease	NOUN
ecj-11500	124	129	,	,	PUNCT
ecj-11500	124	130	serving	serve	VERB
ecj-11500	124	131	as	as	ADP
ecj-11500	124	132	a	a	DET
ecj-11500	124	133	pivotal	pivotal	ADJ
ecj-11500	124	134	guide	guide	NOUN
ecj-11500	124	135	for	for	ADP
ecj-11500	124	136	therapeutic	therapeutic	ADJ
ecj-11500	124	137	interventions	intervention	NOUN
ecj-11500	124	138	and	and	CCONJ
ecj-11500	124	139	anticoagulant	anticoagulant	ADJ
ecj-11500	124	140	treatment	treatment	NOUN
ecj-11500	124	141	monitoring	monitoring	NOUN
ecj-11500	124	142	.	.	PUNCT
ecj-11500	125	1	a	a	DET
ecj-11500	125	2	retrospective	retrospective	ADJ
ecj-11500	125	3	analysis	analysis	NOUN
ecj-11500	125	4	of	of	ADP
ecj-11500	125	5	patients	patient	NOUN
ecj-11500	125	6	undergoing	undergo	VERB
ecj-11500	125	7	cardiac	cardiac	ADJ
ecj-11500	125	8	surgery	surgery	NOUN
ecj-11500	125	9	demonstrated	demonstrate	VERB
ecj-11500	125	10	that	that	SCONJ
ecj-11500	125	11	a	a	DET
ecj-11500	125	12	tegbased	tegbase	VERB
ecj-11500	125	13	algorithm	algorithm	NOUN
ecj-11500	125	14	could	could	AUX
ecj-11500	125	15	not	not	PART
ecj-11500	125	16	only	only	ADV
ecj-11500	125	17	reduce	reduce	VERB
ecj-11500	125	18	postoperative	postoperative	ADJ
ecj-11500	125	19	bleeding	bleeding	NOUN
ecj-11500	125	20	but	but	CCONJ
ecj-11500	125	21	also	also	ADV
ecj-11500	125	22	curtail	curtail	VERB
ecj-11500	125	23	the	the	DET
ecj-11500	125	24	need	need	NOUN
ecj-11500	125	25	for	for	ADP
ecj-11500	125	26	blood	blood	NOUN
ecj-11500	125	27	products.25	products.25	NOUN
ecj-11500	125	28	furthermore	furthermore	ADV
ecj-11500	125	29	,	,	PUNCT
ecj-11500	125	30	this	this	DET
ecj-11500	125	31	approach	approach	NOUN
ecj-11500	125	32	has	have	AUX
ecj-11500	125	33	been	be	AUX
ecj-11500	125	34	associated	associate	VERB
ecj-11500	125	35	with	with	ADP
ecj-11500	125	36	shorter	short	ADJ
ecj-11500	125	37	icu	icu	PROPN
ecj-11500	125	38	stays	stay	NOUN
ecj-11500	125	39	and	and	CCONJ
ecj-11500	125	40	ventilation	ventilation	NOUN
ecj-11500	125	41	durations	duration	NOUN
ecj-11500	125	42	compared	compare	VERB
ecj-11500	125	43	to	to	ADP
ecj-11500	125	44	traditional	traditional	ADJ
ecj-11500	125	45	therapeutic	therapeutic	ADJ
ecj-11500	125	46	strategies	strategy	NOUN
ecj-11500	125	47	.	.	PUNCT
ecj-11500	126	1	in	in	ADP
ecj-11500	126	2	the	the	DET
ecj-11500	126	3	realm	realm	NOUN
ecj-11500	126	4	of	of	ADP
ecj-11500	126	5	liver	liver	NOUN
ecj-11500	126	6	disease	disease	NOUN
ecj-11500	126	7	,	,	PUNCT
ecj-11500	126	8	teg	teg	PROPN
ecj-11500	126	9	has	have	AUX
ecj-11500	126	10	shown	show	VERB
ecj-11500	126	11	significant	significant	ADJ
ecj-11500	126	12	utility	utility	NOUN
ecj-11500	126	13	.	.	PUNCT
ecj-11500	127	1	as	as	SCONJ
ecj-11500	127	2	evidenced	evidence	VERB
ecj-11500	127	3	by	by	ADP
ecj-11500	127	4	the	the	DET
ecj-11500	127	5	manuscript	manuscript	NOUN
ecj-11500	127	6	,	,	PUNCT
ecj-11500	127	7	liver	liver	NOUN
ecj-11500	127	8	disease	disease	NOUN
ecj-11500	127	9	patients	patient	NOUN
ecj-11500	127	10	often	often	ADV
ecj-11500	127	11	present	present	VERB
ecj-11500	127	12	with	with	ADP
ecj-11500	127	13	complex	complex	ADJ
ecj-11500	127	14	coagulopathies	coagulopathie	NOUN
ecj-11500	127	15	due	due	ADP
ecj-11500	127	16	to	to	ADP
ecj-11500	127	17	the	the	DET
ecj-11500	127	18	liver	liver	NOUN
ecj-11500	127	19	’s	’s	PART
ecj-11500	127	20	role	role	NOUN
ecj-11500	127	21	in	in	ADP
ecj-11500	127	22	producing	produce	VERB
ecj-11500	127	23	clotting	clotting	NOUN
ecj-11500	127	24	and	and	CCONJ
ecj-11500	127	25	fibrinolytic	fibrinolytic	ADJ
ecj-11500	127	26	proteins	protein	NOUN
ecj-11500	127	27	.	.	PUNCT
ecj-11500	128	1	teg	teg	NOUN
ecj-11500	128	2	offers	offer	VERB
ecj-11500	128	3	a	a	DET
ecj-11500	128	4	comprehensive	comprehensive	ADJ
ecj-11500	128	5	understanding	understanding	NOUN
ecj-11500	128	6	of	of	ADP
ecj-11500	128	7	these	these	DET
ecj-11500	128	8	patients	patient	NOUN
ecj-11500	128	9	’	’	PART
ecj-11500	128	10	coagulation	coagulation	NOUN
ecj-11500	128	11	profiles	profile	NOUN
ecj-11500	128	12	,	,	PUNCT
ecj-11500	128	13	enabling	enable	VERB
ecj-11500	128	14	clinicians	clinician	NOUN
ecj-11500	128	15	to	to	PART
ecj-11500	128	16	tailor	tailor	VERB
ecj-11500	128	17	hemostatic	hemostatic	ADJ
ecj-11500	128	18	therapies	therapy	NOUN
ecj-11500	128	19	more	more	ADV
ecj-11500	128	20	precisely	precisely	ADV
ecj-11500	128	21	,	,	PUNCT
ecj-11500	128	22	thereby	thereby	ADV
ecj-11500	128	23	potentially	potentially	ADV
ecj-11500	128	24	preventing	prevent	VERB
ecj-11500	128	25	unnecessary	unnecessary	ADJ
ecj-11500	128	26	transfusions	transfusion	NOUN
ecj-11500	128	27	and	and	CCONJ
ecj-11500	128	28	associated	associated	ADJ
ecj-11500	128	29	complications	complication	NOUN
ecj-11500	128	30	.	.	PUNCT
ecj-11500	129	1	this	this	PRON
ecj-11500	129	2	becomes	become	VERB
ecj-11500	129	3	especially	especially	ADV
ecj-11500	129	4	relevant	relevant	ADJ
ecj-11500	129	5	in	in	ADP
ecj-11500	129	6	cirrhotic	cirrhotic	ADJ
ecj-11500	129	7	patients	patient	NOUN
ecj-11500	129	8	,	,	PUNCT
ecj-11500	129	9	where	where	SCONJ
ecj-11500	129	10	traditional	traditional	ADJ
ecj-11500	129	11	coagulation	coagulation	NOUN
ecj-11500	129	12	tests	test	NOUN
ecj-11500	129	13	might	might	AUX
ecj-11500	129	14	not	not	PART
ecj-11500	129	15	reflect	reflect	VERB
ecj-11500	129	16	the	the	DET
ecj-11500	129	17	true	true	ADJ
ecj-11500	129	18	hemostatic	hemostatic	ADJ
ecj-11500	129	19	status	status	NOUN
ecj-11500	129	20	,	,	PUNCT
ecj-11500	129	21	but	but	CCONJ
ecj-11500	129	22	teg	teg	NOUN
ecj-11500	129	23	provides	provide	VERB
ecj-11500	129	24	a	a	DET
ecj-11500	129	25	more	more	ADV
ecj-11500	129	26	nuanced	nuanced	ADJ
ecj-11500	129	27	and	and	CCONJ
ecj-11500	129	28	actionable	actionable	ADJ
ecj-11500	129	29	insight.26	insight.26	ADJ
ecj-11500	129	30	despite	despite	SCONJ
ecj-11500	129	31	its	its	PRON
ecj-11500	129	32	evident	evident	ADJ
ecj-11500	129	33	utility	utility	NOUN
ecj-11500	129	34	,	,	PUNCT
ecj-11500	129	35	specific	specific	ADJ
ecj-11500	129	36	studies	study	NOUN
ecj-11500	129	37	discussing	discuss	VERB
ecj-11500	129	38	the	the	DET
ecj-11500	129	39	direct	direct	ADJ
ecj-11500	129	40	application	application	NOUN
ecj-11500	129	41	of	of	ADP
ecj-11500	129	42	teg	teg	NOUN
ecj-11500	129	43	in	in	ADP
ecj-11500	129	44	the	the	DET
ecj-11500	129	45	context	context	NOUN
ecj-11500	129	46	of	of	ADP
ecj-11500	129	47	prothrombin	prothrombin	ADJ
ecj-11500	129	48	complex	complex	ADJ
ecj-11500	129	49	concentrates	concentrate	NOUN
ecj-11500	129	50	remain	remain	VERB
ecj-11500	129	51	limited	limited	ADJ
ecj-11500	129	52	.	.	PUNCT
ecj-11500	130	1	in	in	ADP
ecj-11500	130	2	conclusion	conclusion	NOUN
ecj-11500	130	3	,	,	PUNCT
ecj-11500	130	4	both	both	DET
ecj-11500	130	5	rotem	rotem	NOUN
ecj-11500	130	6	and	and	CCONJ
ecj-11500	130	7	teg	teg	PROPN
ecj-11500	130	8	stand	stand	NOUN
ecj-11500	130	9	as	as	ADP
ecj-11500	130	10	indispensable	indispensable	ADJ
ecj-11500	130	11	tools	tool	NOUN
ecj-11500	130	12	in	in	ADP
ecj-11500	130	13	the	the	DET
ecj-11500	130	14	management	management	NOUN
ecj-11500	130	15	of	of	ADP
ecj-11500	130	16	bleeding	bleed	VERB
ecj-11500	130	17	disorders	disorder	NOUN
ecj-11500	130	18	,	,	PUNCT
ecj-11500	130	19	presenting	present	VERB
ecj-11500	130	20	an	an	DET
ecj-11500	130	21	avenue	avenue	NOUN
ecj-11500	130	22	to	to	PART
ecj-11500	130	23	augment	augment	VERB
ecj-11500	130	24	the	the	DET
ecj-11500	130	25	safety	safety	NOUN
ecj-11500	130	26	and	and	CCONJ
ecj-11500	130	27	efficacy	efficacy	NOUN
ecj-11500	130	28	of	of	ADP
ecj-11500	130	29	prothrombin	prothrombin	ADJ
ecj-11500	130	30	complex	complex	ADJ
ecj-11500	130	31	concentrate	concentrate	NOUN
ecj-11500	130	32	therapy	therapy	NOUN
ecj-11500	130	33	.	.	PUNCT
ecj-11500	131	1	mini	mini	ADJ
ecj-11500	131	2	review	review	NOUN
ecj-11500	131	3	[	[	X
ecj-11500	131	4	emergency	emergency	NOUN
ecj-11500	131	5	care	care	NOUN
ecj-11500	131	6	journal	journal	NOUN
ecj-11500	131	7	2023	2023	NUM
ecj-11500	131	8	;	;	PUNCT
ecj-11500	131	9	19:11500	19:11500	NUM
ecj-11500	131	10	]	]	X
ecj-11500	132	1	[	[	X
ecj-11500	132	2	page	page	NOUN
ecj-11500	132	3	8	8	NUM
ecj-11500	132	4	]	]	X
ecj-11500	132	5	non	non	ADJ
ecj-11500	132	6	-co	-co	PROPN
ecj-11500	132	7	mmerc	mmerc	PROPN
ecj-11500	132	8	ial	ial	PROPN
ecj-11500	132	9	us	us	PROPN
ecj-11500	132	10	e	e	NOUN
ecj-11500	132	11	o	o	NOUN
ecj-11500	132	12	nly	nly	ADV
ecj-11500	132	13	parameters	parameter	NOUN
ecj-11500	132	14	of	of	ADP
ecj-11500	132	15	thromboelastometry	thromboelastometry	NOUN
ecj-11500	132	16	(	(	PUNCT
ecj-11500	132	17	rotem	rotem	PROPN
ecj-11500	132	18	)	)	PUNCT
ecj-11500	132	19	and	and	CCONJ
ecj-11500	132	20	thromboelastography	thromboelastography	NOUN
ecj-11500	132	21	(	(	PUNCT
ecj-11500	132	22	teg	teg	PROPN
ecj-11500	132	23	)	)	PUNCT
ecj-11500	132	24	thromboelastometry	thromboelastometry	NOUN
ecj-11500	132	25	(	(	PUNCT
ecj-11500	132	26	rotem	rotem	PROPN
ecj-11500	132	27	)	)	PUNCT
ecj-11500	132	28	and	and	CCONJ
ecj-11500	132	29	thromboelastography	thromboelastography	NOUN
ecj-11500	132	30	(	(	PUNCT
ecj-11500	132	31	teg	teg	NOUN
ecj-11500	132	32	)	)	PUNCT
ecj-11500	132	33	are	be	AUX
ecj-11500	132	34	viscoelastic	viscoelastic	ADJ
ecj-11500	132	35	tests	test	NOUN
ecj-11500	132	36	that	that	PRON
ecj-11500	132	37	provide	provide	VERB
ecj-11500	132	38	a	a	DET
ecj-11500	132	39	comprehensive	comprehensive	ADJ
ecj-11500	132	40	assessment	assessment	NOUN
ecj-11500	132	41	of	of	ADP
ecj-11500	132	42	the	the	DET
ecj-11500	132	43	coagulation	coagulation	NOUN
ecj-11500	132	44	process	process	NOUN
ecj-11500	132	45	.	.	PUNCT
ecj-11500	133	1	they	they	PRON
ecj-11500	133	2	measure	measure	VERB
ecj-11500	133	3	various	various	ADJ
ecj-11500	133	4	parameters	parameter	NOUN
ecj-11500	133	5	that	that	PRON
ecj-11500	133	6	reflect	reflect	VERB
ecj-11500	133	7	different	different	ADJ
ecj-11500	133	8	aspects	aspect	NOUN
ecj-11500	133	9	of	of	ADP
ecj-11500	133	10	clot	clot	NOUN
ecj-11500	133	11	formation	formation	NOUN
ecj-11500	133	12	,	,	PUNCT
ecj-11500	133	13	stabilization	stabilization	NOUN
ecj-11500	133	14	,	,	PUNCT
ecj-11500	133	15	and	and	CCONJ
ecj-11500	133	16	dissolution.27,28	dissolution.27,28	PROPN
ecj-11500	133	17	rotem	rotem	PROPN
ecj-11500	133	18	parameters	parameter	VERB
ecj-11500	133	19	the	the	DET
ecj-11500	133	20	parameters	parameter	NOUN
ecj-11500	133	21	of	of	ADP
ecj-11500	133	22	rotem	rotem	NOUN
ecj-11500	133	23	include	include	VERB
ecj-11500	133	24	:	:	PUNCT
ecj-11500	133	25	clotting	clot	VERB
ecj-11500	133	26	time	time	NOUN
ecj-11500	133	27	(	(	PUNCT
ecj-11500	133	28	ct	ct	X
ecj-11500	133	29	):	):	PUNCT
ecj-11500	133	30	this	this	PRON
ecj-11500	133	31	is	be	AUX
ecj-11500	133	32	the	the	DET
ecj-11500	133	33	time	time	NOUN
ecj-11500	133	34	from	from	ADP
ecj-11500	133	35	the	the	DET
ecj-11500	133	36	start	start	NOUN
ecj-11500	133	37	of	of	ADP
ecj-11500	133	38	the	the	DET
ecj-11500	133	39	test	test	NOUN
ecj-11500	133	40	until	until	SCONJ
ecj-11500	133	41	the	the	DET
ecj-11500	133	42	clot	clot	NOUN
ecj-11500	133	43	starts	start	VERB
ecj-11500	133	44	to	to	PART
ecj-11500	133	45	form	form	VERB
ecj-11500	133	46	.	.	PUNCT
ecj-11500	134	1	it	it	PRON
ecj-11500	134	2	is	be	AUX
ecj-11500	134	3	a	a	DET
ecj-11500	134	4	measure	measure	NOUN
ecj-11500	134	5	of	of	ADP
ecj-11500	134	6	the	the	DET
ecj-11500	134	7	speed	speed	NOUN
ecj-11500	134	8	of	of	ADP
ecj-11500	134	9	clot	clot	NOUN
ecj-11500	134	10	initiation	initiation	NOUN
ecj-11500	134	11	and	and	CCONJ
ecj-11500	134	12	is	be	AUX
ecj-11500	134	13	influenced	influence	VERB
ecj-11500	134	14	by	by	ADP
ecj-11500	134	15	the	the	DET
ecj-11500	134	16	coagulation	coagulation	NOUN
ecj-11500	134	17	factors	factor	NOUN
ecj-11500	134	18	and	and	CCONJ
ecj-11500	134	19	their	their	PRON
ecj-11500	134	20	inhibitors	inhibitor	NOUN
ecj-11500	134	21	.	.	PUNCT
ecj-11500	135	1	clot	clot	NOUN
ecj-11500	135	2	formation	formation	NOUN
ecj-11500	135	3	time	time	NOUN
ecj-11500	135	4	(	(	PUNCT
ecj-11500	135	5	cft	cft	PROPN
ecj-11500	135	6	):	):	PUNCT
ecj-11500	135	7	this	this	PRON
ecj-11500	135	8	is	be	AUX
ecj-11500	135	9	the	the	DET
ecj-11500	135	10	time	time	NOUN
ecj-11500	135	11	from	from	ADP
ecj-11500	135	12	the	the	DET
ecj-11500	135	13	end	end	NOUN
ecj-11500	135	14	of	of	ADP
ecj-11500	135	15	the	the	DET
ecj-11500	135	16	ct	ct	PROPN
ecj-11500	135	17	until	until	SCONJ
ecj-11500	135	18	a	a	DET
ecj-11500	135	19	certain	certain	ADJ
ecj-11500	135	20	level	level	NOUN
ecj-11500	135	21	of	of	ADP
ecj-11500	135	22	clot	clot	NOUN
ecj-11500	135	23	firmness	firmness	NOUN
ecj-11500	135	24	is	be	AUX
ecj-11500	135	25	reached	reach	VERB
ecj-11500	135	26	.	.	PUNCT
ecj-11500	136	1	it	it	PRON
ecj-11500	136	2	is	be	AUX
ecj-11500	136	3	a	a	DET
ecj-11500	136	4	measure	measure	NOUN
ecj-11500	136	5	of	of	ADP
ecj-11500	136	6	the	the	DET
ecj-11500	136	7	speed	speed	NOUN
ecj-11500	136	8	of	of	ADP
ecj-11500	136	9	clot	clot	NOUN
ecj-11500	136	10	growth	growth	NOUN
ecj-11500	136	11	and	and	CCONJ
ecj-11500	136	12	is	be	AUX
ecj-11500	136	13	influenced	influence	VERB
ecj-11500	136	14	by	by	ADP
ecj-11500	136	15	the	the	DET
ecj-11500	136	16	platelets	platelet	NOUN
ecj-11500	136	17	and	and	CCONJ
ecj-11500	136	18	fibrinogen	fibrinogen	NOUN
ecj-11500	136	19	.	.	PUNCT
ecj-11500	137	1	maximum	maximum	ADJ
ecj-11500	137	2	clot	clot	NOUN
ecj-11500	137	3	firmness	firmness	NOUN
ecj-11500	137	4	(	(	PUNCT
ecj-11500	137	5	mcf	mcf	NOUN
ecj-11500	137	6	):	):	PUNCT
ecj-11500	137	7	this	this	PRON
ecj-11500	137	8	is	be	AUX
ecj-11500	137	9	the	the	DET
ecj-11500	137	10	maximum	maximum	ADJ
ecj-11500	137	11	amplitude	amplitude	NOUN
ecj-11500	137	12	of	of	ADP
ecj-11500	137	13	the	the	DET
ecj-11500	137	14	clot	clot	NOUN
ecj-11500	137	15	firmness	firmness	NOUN
ecj-11500	137	16	curve	curve	NOUN
ecj-11500	137	17	.	.	PUNCT
ecj-11500	138	1	it	it	PRON
ecj-11500	138	2	is	be	AUX
ecj-11500	138	3	a	a	DET
ecj-11500	138	4	measure	measure	NOUN
ecj-11500	138	5	of	of	ADP
ecj-11500	138	6	the	the	DET
ecj-11500	138	7	maximum	maximum	ADJ
ecj-11500	138	8	strength	strength	NOUN
ecj-11500	138	9	of	of	ADP
ecj-11500	138	10	the	the	DET
ecj-11500	138	11	clot	clot	NOUN
ecj-11500	138	12	and	and	CCONJ
ecj-11500	138	13	is	be	AUX
ecj-11500	138	14	influenced	influence	VERB
ecj-11500	138	15	by	by	ADP
ecj-11500	138	16	the	the	DET
ecj-11500	138	17	platelets	platelet	NOUN
ecj-11500	138	18	and	and	CCONJ
ecj-11500	138	19	fibrinogen	fibrinogen	NOUN
ecj-11500	138	20	.	.	PUNCT
ecj-11500	138	21	amplitude	amplitude	NOUN
ecj-11500	138	22	at	at	ADP
ecj-11500	138	23	5	5	NUM
ecj-11500	138	24	minutes	minute	NOUN
ecj-11500	138	25	(	(	PUNCT
ecj-11500	138	26	a5	a5	NUM
ecj-11500	138	27	):	):	PUNCT
ecj-11500	138	28	this	this	PRON
ecj-11500	138	29	is	be	AUX
ecj-11500	138	30	the	the	DET
ecj-11500	138	31	amplitude	amplitude	NOUN
ecj-11500	138	32	of	of	ADP
ecj-11500	138	33	the	the	DET
ecj-11500	138	34	clot	clot	NOUN
ecj-11500	138	35	firmness	firmness	NOUN
ecj-11500	138	36	curve	curve	NOUN
ecj-11500	138	37	at	at	ADP
ecj-11500	138	38	5	5	NUM
ecj-11500	138	39	minutes	minute	NOUN
ecj-11500	138	40	after	after	ADP
ecj-11500	138	41	the	the	DET
ecj-11500	138	42	ct	ct	PROPN
ecj-11500	138	43	.	.	PUNCT
ecj-11500	139	1	it	it	PRON
ecj-11500	139	2	is	be	AUX
ecj-11500	139	3	a	a	DET
ecj-11500	139	4	measure	measure	NOUN
ecj-11500	139	5	of	of	ADP
ecj-11500	139	6	the	the	DET
ecj-11500	139	7	early	early	ADJ
ecj-11500	139	8	development	development	NOUN
ecj-11500	139	9	of	of	ADP
ecj-11500	139	10	the	the	DET
ecj-11500	139	11	clot	clot	NOUN
ecj-11500	139	12	strength	strength	NOUN
ecj-11500	139	13	.	.	PUNCT
ecj-11500	140	1	clot	clot	NOUN
ecj-11500	140	2	lysis	lysis	NOUN
ecj-11500	140	3	index	index	NOUN
ecj-11500	140	4	(	(	PUNCT
ecj-11500	140	5	cli	cli	NOUN
ecj-11500	140	6	):	):	PUNCT
ecj-11500	140	7	this	this	PRON
ecj-11500	140	8	is	be	AUX
ecj-11500	140	9	a	a	DET
ecj-11500	140	10	measure	measure	NOUN
ecj-11500	140	11	of	of	ADP
ecj-11500	140	12	the	the	DET
ecj-11500	140	13	stability	stability	NOUN
ecj-11500	140	14	of	of	ADP
ecj-11500	140	15	the	the	DET
ecj-11500	140	16	clot	clot	NOUN
ecj-11500	140	17	over	over	ADP
ecj-11500	140	18	time	time	NOUN
ecj-11500	140	19	.	.	PUNCT
ecj-11500	141	1	it	it	PRON
ecj-11500	141	2	is	be	AUX
ecj-11500	141	3	calculated	calculate	VERB
ecj-11500	141	4	as	as	ADP
ecj-11500	141	5	the	the	DET
ecj-11500	141	6	percentage	percentage	NOUN
ecj-11500	141	7	of	of	ADP
ecj-11500	141	8	the	the	DET
ecj-11500	141	9	mcf	mcf	NOUN
ecj-11500	141	10	that	that	PRON
ecj-11500	141	11	remains	remain	VERB
ecj-11500	141	12	at	at	ADP
ecj-11500	141	13	a	a	DET
ecj-11500	141	14	certain	certain	ADJ
ecj-11500	141	15	time	time	NOUN
ecj-11500	141	16	after	after	ADP
ecj-11500	141	17	the	the	DET
ecj-11500	141	18	mcf	mcf	NOUN
ecj-11500	141	19	(	(	PUNCT
ecj-11500	141	20	figure	figure	NOUN
ecj-11500	141	21	1	1	NUM
ecj-11500	141	22	)	)	PUNCT
ecj-11500	141	23	.	.	PUNCT
ecj-11500	142	1	these	these	DET
ecj-11500	142	2	parameters	parameter	NOUN
ecj-11500	142	3	are	be	AUX
ecj-11500	142	4	measured	measure	VERB
ecj-11500	142	5	in	in	ADP
ecj-11500	142	6	different	different	ADJ
ecj-11500	142	7	assays	assay	NOUN
ecj-11500	142	8	,	,	PUNCT
ecj-11500	142	9	including	include	VERB
ecj-11500	142	10	intem	intem	NOUN
ecj-11500	142	11	,	,	PUNCT
ecj-11500	142	12	extem	extem	NOUN
ecj-11500	142	13	,	,	PUNCT
ecj-11500	142	14	fibtem	fibtem	NOUN
ecj-11500	142	15	,	,	PUNCT
ecj-11500	142	16	aptem	aptem	NOUN
ecj-11500	142	17	,	,	PUNCT
ecj-11500	142	18	and	and	CCONJ
ecj-11500	142	19	heptem.29	heptem.29	NOUN
ecj-11500	142	20	intem	intem	NOUN
ecj-11500	142	21	:	:	PUNCT
ecj-11500	142	22	this	this	DET
ecj-11500	142	23	assay	assay	NOUN
ecj-11500	142	24	is	be	AUX
ecj-11500	142	25	sensitive	sensitive	ADJ
ecj-11500	142	26	to	to	ADP
ecj-11500	142	27	the	the	DET
ecj-11500	142	28	intrinsic	intrinsic	ADJ
ecj-11500	142	29	pathway	pathway	NOUN
ecj-11500	142	30	of	of	ADP
ecj-11500	142	31	coagulation	coagulation	NOUN
ecj-11500	142	32	and	and	CCONJ
ecj-11500	142	33	is	be	AUX
ecj-11500	142	34	used	use	VERB
ecj-11500	142	35	to	to	PART
ecj-11500	142	36	assess	assess	VERB
ecj-11500	142	37	the	the	DET
ecj-11500	142	38	effect	effect	NOUN
ecj-11500	142	39	of	of	ADP
ecj-11500	142	40	heparin	heparin	NOUN
ecj-11500	142	41	-	-	PUNCT
ecj-11500	142	42	like	like	ADJ
ecj-11500	142	43	anticoagulants	anticoagulant	NOUN
ecj-11500	142	44	.	.	PUNCT
ecj-11500	143	1	extem	extem	NOUN
ecj-11500	143	2	:	:	PUNCT
ecj-11500	143	3	this	this	DET
ecj-11500	143	4	assay	assay	NOUN
ecj-11500	143	5	is	be	AUX
ecj-11500	143	6	sensitive	sensitive	ADJ
ecj-11500	143	7	to	to	ADP
ecj-11500	143	8	the	the	DET
ecj-11500	143	9	extrinsic	extrinsic	ADJ
ecj-11500	143	10	pathway	pathway	NOUN
ecj-11500	143	11	of	of	ADP
ecj-11500	143	12	coagulation	coagulation	NOUN
ecj-11500	143	13	and	and	CCONJ
ecj-11500	143	14	is	be	AUX
ecj-11500	143	15	used	use	VERB
ecj-11500	143	16	to	to	PART
ecj-11500	143	17	assess	assess	VERB
ecj-11500	143	18	the	the	DET
ecj-11500	143	19	effect	effect	NOUN
ecj-11500	143	20	of	of	ADP
ecj-11500	143	21	tissue	tissue	NOUN
ecj-11500	143	22	factor	factor	NOUN
ecj-11500	143	23	.	.	PUNCT
ecj-11500	144	1	fibtem	fibtem	NOUN
ecj-11500	144	2	:	:	PUNCT
ecj-11500	144	3	this	this	DET
ecj-11500	144	4	assay	assay	NOUN
ecj-11500	144	5	is	be	AUX
ecj-11500	144	6	used	use	VERB
ecj-11500	144	7	to	to	PART
ecj-11500	144	8	assess	assess	VERB
ecj-11500	144	9	fibrinogen	fibrinogen	NOUN
ecj-11500	144	10	function	function	NOUN
ecj-11500	144	11	.	.	PUNCT
ecj-11500	145	1	aptem	aptem	PROPN
ecj-11500	145	2	:	:	PUNCT
ecj-11500	145	3	this	this	DET
ecj-11500	145	4	assay	assay	NOUN
ecj-11500	145	5	is	be	AUX
ecj-11500	145	6	used	use	VERB
ecj-11500	145	7	to	to	PART
ecj-11500	145	8	assess	assess	VERB
ecj-11500	145	9	fibrinolysis	fibrinolysis	NOUN
ecj-11500	145	10	by	by	ADP
ecj-11500	145	11	adding	add	VERB
ecj-11500	145	12	aprotinin	aprotinin	NOUN
ecj-11500	145	13	,	,	PUNCT
ecj-11500	145	14	a	a	DET
ecj-11500	145	15	fibrinolysis	fibrinolysis	NOUN
ecj-11500	145	16	inhibitor	inhibitor	NOUN
ecj-11500	145	17	,	,	PUNCT
ecj-11500	145	18	to	to	ADP
ecj-11500	145	19	the	the	DET
ecj-11500	145	20	extem	extem	NOUN
ecj-11500	145	21	assay	assay	VERB
ecj-11500	145	22	.	.	PUNCT
ecj-11500	146	1	heptem	heptem	NOUN
ecj-11500	146	2	:	:	PUNCT
ecj-11500	147	1	this	this	DET
ecj-11500	147	2	assay	assay	NOUN
ecj-11500	147	3	is	be	AUX
ecj-11500	147	4	used	use	VERB
ecj-11500	147	5	to	to	PART
ecj-11500	147	6	assess	assess	VERB
ecj-11500	147	7	the	the	DET
ecj-11500	147	8	effect	effect	NOUN
ecj-11500	147	9	of	of	ADP
ecj-11500	147	10	heparin	heparin	NOUN
ecj-11500	147	11	by	by	ADP
ecj-11500	147	12	adding	add	VERB
ecj-11500	147	13	heparinase	heparinase	NOUN
ecj-11500	147	14	to	to	ADP
ecj-11500	147	15	the	the	DET
ecj-11500	147	16	intem	intem	NOUN
ecj-11500	147	17	assay	assay	VERB
ecj-11500	147	18	.	.	PUNCT
ecj-11500	148	1	in	in	ADP
ecj-11500	148	2	a	a	DET
ecj-11500	148	3	study	study	NOUN
ecj-11500	148	4	titled	title	VERB
ecj-11500	148	5	“	"	PUNCT
ecj-11500	148	6	thromboelastometry	thromboelastometry	NOUN
ecj-11500	148	7	-	-	PUNCT
ecj-11500	148	8	guided	guide	VERB
ecj-11500	148	9	hemostatic	hemostatic	ADJ
ecj-11500	148	10	resuscitation	resuscitation	NOUN
ecj-11500	148	11	in	in	ADP
ecj-11500	148	12	severely	severely	ADV
ecj-11500	148	13	injured	injure	VERB
ecj-11500	148	14	patients	patient	NOUN
ecj-11500	148	15	:	:	PUNCT
ecj-11500	148	16	a	a	DET
ecj-11500	148	17	propensity	propensity	NOUN
ecj-11500	148	18	scorematched	scorematche	VERB
ecj-11500	148	19	study	study	NOUN
ecj-11500	148	20	”	"	PUNCT
ecj-11500	148	21	,	,	PUNCT
ecj-11500	148	22	the	the	DET
ecj-11500	148	23	authors	author	NOUN
ecj-11500	148	24	used	use	VERB
ecj-11500	148	25	rotem	rotem	NOUN
ecj-11500	148	26	to	to	PART
ecj-11500	148	27	guide	guide	VERB
ecj-11500	148	28	the	the	DET
ecj-11500	148	29	administration	administration	NOUN
ecj-11500	148	30	of	of	ADP
ecj-11500	148	31	blood	blood	NOUN
ecj-11500	148	32	products	product	NOUN
ecj-11500	148	33	and	and	CCONJ
ecj-11500	148	34	coagulation	coagulation	NOUN
ecj-11500	148	35	factors	factor	NOUN
ecj-11500	148	36	in	in	ADP
ecj-11500	148	37	severely	severely	ADV
ecj-11500	148	38	injured	injure	VERB
ecj-11500	148	39	patients	patient	NOUN
ecj-11500	148	40	.	.	PUNCT
ecj-11500	149	1	they	they	PRON
ecj-11500	149	2	found	find	VERB
ecj-11500	149	3	that	that	SCONJ
ecj-11500	149	4	a	a	DET
ecj-11500	149	5	rotem	rotem	NOUN
ecj-11500	149	6	-	-	PUNCT
ecj-11500	149	7	based	base	VERB
ecj-11500	149	8	strategy	strategy	NOUN
ecj-11500	149	9	was	be	AUX
ecj-11500	149	10	associated	associate	VERB
ecj-11500	149	11	with	with	ADP
ecj-11500	149	12	an	an	DET
ecj-11500	149	13	increased	increase	VERB
ecj-11500	149	14	probability	probability	NOUN
ecj-11500	149	15	of	of	ADP
ecj-11500	149	16	being	be	AUX
ecj-11500	149	17	alive	alive	ADJ
ecj-11500	149	18	and	and	CCONJ
ecj-11500	149	19	free	free	ADJ
ecj-11500	149	20	of	of	ADP
ecj-11500	149	21	massive	massive	ADJ
ecj-11500	149	22	transfusion	transfusion	NOUN
ecj-11500	149	23	,	,	PUNCT
ecj-11500	149	24	without	without	ADP
ecj-11500	149	25	any	any	DET
ecj-11500	149	26	difference	difference	NOUN
ecj-11500	149	27	in	in	ADP
ecj-11500	149	28	mortality	mortality	NOUN
ecj-11500	149	29	at	at	ADP
ecj-11500	149	30	24	24	NUM
ecj-11500	149	31	hours	hour	NOUN
ecj-11500	149	32	or	or	CCONJ
ecj-11500	149	33	at	at	ADP
ecj-11500	149	34	day	day	NOUN
ecj-11500	149	35	28	28	NUM
ecj-11500	149	36	.	.	PUNCT
ecj-11500	150	1	the	the	DET
ecj-11500	150	2	rotem	rotem	NOUN
ecj-11500	150	3	-	-	PUNCT
ecj-11500	150	4	based	base	VERB
ecj-11500	150	5	strategy	strategy	NOUN
ecj-11500	150	6	was	be	AUX
ecj-11500	150	7	also	also	ADV
ecj-11500	150	8	associated	associate	VERB
ecj-11500	150	9	with	with	ADP
ecj-11500	150	10	a	a	DET
ecj-11500	150	11	significant	significant	ADJ
ecj-11500	150	12	decrease	decrease	NOUN
ecj-11500	150	13	in	in	ADP
ecj-11500	150	14	the	the	DET
ecj-11500	150	15	use	use	NOUN
ecj-11500	150	16	of	of	ADP
ecj-11500	150	17	blood	blood	NOUN
ecj-11500	150	18	products	product	NOUN
ecj-11500	150	19	and	and	CCONJ
ecj-11500	150	20	their	their	PRON
ecj-11500	150	21	related	related	ADJ
ecj-11500	150	22	cost.28	cost.28	NOUN
ecj-11500	150	23	teg	teg	PROPN
ecj-11500	150	24	parameters	parameter	NOUN
ecj-11500	150	25	teg	teg	PROPN
ecj-11500	150	26	measures	measure	VERB
ecj-11500	150	27	several	several	ADJ
ecj-11500	150	28	parameters	parameter	NOUN
ecj-11500	150	29	,	,	PUNCT
ecj-11500	150	30	including	include	VERB
ecj-11500	150	31	reaction	reaction	NOUN
ecj-11500	150	32	time	time	NOUN
ecj-11500	150	33	(	(	PUNCT
ecj-11500	150	34	r	r	NOUN
ecj-11500	150	35	)	)	PUNCT
ecj-11500	150	36	,	,	PUNCT
ecj-11500	150	37	kinetics	kinetic	NOUN
ecj-11500	150	38	time	time	NOUN
ecj-11500	150	39	(	(	PUNCT
ecj-11500	150	40	k	k	NOUN
ecj-11500	150	41	)	)	PUNCT
ecj-11500	150	42	,	,	PUNCT
ecj-11500	150	43	alpha	alpha	NOUN
ecj-11500	150	44	angle	angle	NOUN
ecj-11500	150	45	(	(	PUNCT
ecj-11500	150	46	α	α	NOUN
ecj-11500	150	47	)	)	PUNCT
ecj-11500	150	48	,	,	PUNCT
ecj-11500	150	49	maximum	maximum	ADJ
ecj-11500	150	50	amplitude	amplitude	NOUN
ecj-11500	150	51	(	(	PUNCT
ecj-11500	150	52	ma	ma	PROPN
ecj-11500	150	53	)	)	PUNCT
ecj-11500	150	54	,	,	PUNCT
ecj-11500	150	55	and	and	CCONJ
ecj-11500	150	56	lysis	lysis	NOUN
ecj-11500	150	57	at	at	ADP
ecj-11500	150	58	30	30	NUM
ecj-11500	150	59	minutes	minute	NOUN
ecj-11500	150	60	(	(	PUNCT
ecj-11500	150	61	ly30	ly30	PROPN
ecj-11500	150	62	)	)	PUNCT
ecj-11500	150	63	(	(	PUNCT
ecj-11500	150	64	figure	figure	NOUN
ecj-11500	150	65	2	2	NUM
ecj-11500	150	66	):	):	PUNCT
ecj-11500	150	67	r	r	NOUN
ecj-11500	150	68	-	-	PUNCT
ecj-11500	150	69	time	time	NOUN
ecj-11500	150	70	(	(	PUNCT
ecj-11500	150	71	reaction	reaction	NOUN
ecj-11500	150	72	time	time	NOUN
ecj-11500	150	73	):	):	PUNCT
ecj-11500	150	74	this	this	PRON
ecj-11500	150	75	is	be	AUX
ecj-11500	150	76	the	the	DET
ecj-11500	150	77	time	time	NOUN
ecj-11500	150	78	from	from	ADP
ecj-11500	150	79	the	the	DET
ecj-11500	150	80	start	start	NOUN
ecj-11500	150	81	of	of	ADP
ecj-11500	150	82	the	the	DET
ecj-11500	150	83	test	test	NOUN
ecj-11500	150	84	until	until	ADP
ecj-11500	150	85	initial	initial	ADJ
ecj-11500	150	86	fibrin	fibrin	NOUN
ecj-11500	150	87	formation	formation	NOUN
ecj-11500	150	88	.	.	PUNCT
ecj-11500	151	1	k	k	X
ecj-11500	151	2	-	-	PUNCT
ecj-11500	151	3	time	time	NOUN
ecj-11500	151	4	(	(	PUNCT
ecj-11500	151	5	kinetics	kinetic	NOUN
ecj-11500	151	6	time	time	NOUN
ecj-11500	151	7	):	):	PUNCT
ecj-11500	151	8	this	this	PRON
ecj-11500	151	9	is	be	AUX
ecj-11500	151	10	the	the	DET
ecj-11500	151	11	time	time	NOUN
ecj-11500	151	12	from	from	ADP
ecj-11500	151	13	the	the	DET
ecj-11500	151	14	end	end	NOUN
ecj-11500	151	15	of	of	ADP
ecj-11500	151	16	r	r	NOUN
ecj-11500	151	17	-	-	PUNCT
ecj-11500	151	18	time	time	NOUN
ecj-11500	151	19	to	to	ADP
ecj-11500	151	20	a	a	DET
ecj-11500	151	21	certain	certain	ADJ
ecj-11500	151	22	level	level	NOUN
ecj-11500	151	23	of	of	ADP
ecj-11500	151	24	clot	clot	NOUN
ecj-11500	151	25	firmness	firmness	NOUN
ecj-11500	151	26	.	.	PUNCT
ecj-11500	152	1	alpha	alpha	PROPN
ecj-11500	152	2	angle	angle	NOUN
ecj-11500	152	3	(	(	PUNCT
ecj-11500	152	4	α	α	NOUN
ecj-11500	152	5	):	):	PUNCT
ecj-11500	152	6	this	this	PRON
ecj-11500	152	7	is	be	AUX
ecj-11500	152	8	the	the	DET
ecj-11500	152	9	angle	angle	NOUN
ecj-11500	152	10	formed	form	VERB
ecj-11500	152	11	by	by	ADP
ecj-11500	152	12	the	the	DET
ecj-11500	152	13	slope	slope	NOUN
ecj-11500	152	14	from	from	ADP
ecj-11500	152	15	the	the	DET
ecj-11500	152	16	end	end	NOUN
ecj-11500	152	17	of	of	ADP
ecj-11500	152	18	r	r	NOUN
ecj-11500	152	19	-	-	PUNCT
ecj-11500	152	20	time	time	NOUN
ecj-11500	152	21	to	to	ADP
ecj-11500	152	22	k	k	NOUN
ecj-11500	152	23	-	-	NOUN
ecj-11500	152	24	time	time	NOUN
ecj-11500	152	25	,	,	PUNCT
ecj-11500	152	26	representing	represent	VERB
ecj-11500	152	27	the	the	DET
ecj-11500	152	28	speed	speed	NOUN
ecj-11500	152	29	of	of	ADP
ecj-11500	152	30	clot	clot	NOUN
ecj-11500	152	31	formation	formation	NOUN
ecj-11500	152	32	.	.	PUNCT
ecj-11500	153	1	ma	ma	PROPN
ecj-11500	153	2	(	(	PUNCT
ecj-11500	153	3	maximum	maximum	ADJ
ecj-11500	153	4	amplitude	amplitude	NOUN
ecj-11500	153	5	):	):	PUNCT
ecj-11500	153	6	this	this	PRON
ecj-11500	153	7	is	be	AUX
ecj-11500	153	8	the	the	DET
ecj-11500	153	9	maximum	maximum	ADJ
ecj-11500	153	10	strength	strength	NOUN
ecj-11500	153	11	of	of	ADP
ecj-11500	153	12	the	the	DET
ecj-11500	153	13	clot	clot	NOUN
ecj-11500	153	14	,	,	PUNCT
ecj-11500	153	15	representing	represent	VERB
ecj-11500	153	16	the	the	DET
ecj-11500	153	17	overall	overall	ADJ
ecj-11500	153	18	stability	stability	NOUN
ecj-11500	153	19	of	of	ADP
ecj-11500	153	20	the	the	DET
ecj-11500	153	21	clot	clot	NOUN
ecj-11500	153	22	.	.	PUNCT
ecj-11500	154	1	ly30	ly30	PROPN
ecj-11500	154	2	(	(	PUNCT
ecj-11500	154	3	lysis	lysis	NOUN
ecj-11500	154	4	at	at	ADP
ecj-11500	154	5	30	30	NUM
ecj-11500	154	6	minutes	minute	NOUN
ecj-11500	154	7	):	):	PUNCT
ecj-11500	154	8	this	this	PRON
ecj-11500	154	9	is	be	AUX
ecj-11500	154	10	the	the	DET
ecj-11500	154	11	percentage	percentage	NOUN
ecj-11500	154	12	decrease	decrease	NOUN
ecj-11500	154	13	in	in	ADP
ecj-11500	154	14	amplitude	amplitude	NOUN
ecj-11500	154	15	at	at	ADP
ecj-11500	154	16	30	30	NUM
ecj-11500	154	17	minutes	minute	NOUN
ecj-11500	154	18	after	after	ADP
ecj-11500	154	19	ma	ma	PROPN
ecj-11500	154	20	,	,	PUNCT
ecj-11500	154	21	representing	represent	VERB
ecj-11500	154	22	the	the	DET
ecj-11500	154	23	degree	degree	NOUN
ecj-11500	154	24	of	of	ADP
ecj-11500	154	25	fibrinolysis	fibrinolysis	NOUN
ecj-11500	154	26	.	.	PUNCT
ecj-11500	155	1	both	both	DET
ecj-11500	155	2	rotem	rotem	PROPN
ecj-11500	155	3	and	and	CCONJ
ecj-11500	155	4	teg	teg	PROPN
ecj-11500	155	5	can	can	AUX
ecj-11500	155	6	be	be	AUX
ecj-11500	155	7	used	use	VERB
ecj-11500	155	8	to	to	PART
ecj-11500	155	9	guide	guide	VERB
ecj-11500	155	10	the	the	DET
ecj-11500	155	11	administration	administration	NOUN
ecj-11500	155	12	of	of	ADP
ecj-11500	155	13	prothrombin	prothrombin	ADJ
ecj-11500	155	14	complex	complex	ADJ
ecj-11500	155	15	concentrates	concentrate	NOUN
ecj-11500	155	16	and	and	CCONJ
ecj-11500	155	17	other	other	ADJ
ecj-11500	155	18	hemostatic	hemostatic	ADJ
ecj-11500	155	19	therapies	therapy	NOUN
ecj-11500	155	20	in	in	ADP
ecj-11500	155	21	various	various	ADJ
ecj-11500	155	22	clinical	clinical	ADJ
ecj-11500	155	23	settings	setting	NOUN
ecj-11500	155	24	.	.	PUNCT
ecj-11500	156	1	thromboelastography	thromboelastography	NOUN
ecj-11500	156	2	provides	provide	VERB
ecj-11500	156	3	a	a	DET
ecj-11500	156	4	comprehensive	comprehensive	ADJ
ecj-11500	156	5	evaluation	evaluation	NOUN
ecj-11500	156	6	of	of	ADP
ecj-11500	156	7	hemostasis	hemostasis	NOUN
ecj-11500	156	8	,	,	PUNCT
ecj-11500	156	9	starting	start	VERB
ecj-11500	156	10	from	from	ADP
ecj-11500	156	11	the	the	DET
ecj-11500	156	12	initiation	initiation	NOUN
ecj-11500	156	13	of	of	ADP
ecj-11500	156	14	clotting	clot	VERB
ecj-11500	156	15	to	to	PART
ecj-11500	156	16	fibrinolysis	fibrinolysis	VERB
ecj-11500	156	17	.	.	PUNCT
ecj-11500	157	1	key	key	ADJ
ecj-11500	157	2	components	component	NOUN
ecj-11500	157	3	involved	involve	VERB
ecj-11500	157	4	include	include	VERB
ecj-11500	157	5	:	:	PUNCT
ecj-11500	157	6	platelets	platelet	VERB
ecj-11500	157	7	:	:	PUNCT
ecj-11500	157	8	they	they	PRON
ecj-11500	157	9	play	play	VERB
ecj-11500	157	10	a	a	DET
ecj-11500	157	11	pivotal	pivotal	ADJ
ecj-11500	157	12	role	role	NOUN
ecj-11500	157	13	in	in	ADP
ecj-11500	157	14	clot	clot	NOUN
ecj-11500	157	15	formation	formation	NOUN
ecj-11500	157	16	.	.	PUNCT
ecj-11500	158	1	the	the	DET
ecj-11500	158	2	amplitude	amplitude	NOUN
ecj-11500	158	3	of	of	ADP
ecj-11500	158	4	the	the	DET
ecj-11500	158	5	teg	teg	NOUN
ecj-11500	158	6	tracing	trace	VERB
ecj-11500	158	7	during	during	ADP
ecj-11500	158	8	the	the	DET
ecj-11500	158	9	initial	initial	ADJ
ecj-11500	158	10	5	5	NUM
ecj-11500	158	11	-	-	SYM
ecj-11500	158	12	10	10	NUM
ecj-11500	158	13	minutes	minute	NOUN
ecj-11500	158	14	,	,	PUNCT
ecj-11500	158	15	known	know	VERB
ecj-11500	158	16	as	as	ADP
ecj-11500	158	17	the	the	DET
ecj-11500	158	18	r	r	NOUN
ecj-11500	158	19	-	-	PUNCT
ecj-11500	158	20	time	time	NOUN
ecj-11500	158	21	,	,	PUNCT
ecj-11500	158	22	is	be	AUX
ecj-11500	158	23	influenced	influence	VERB
ecj-11500	158	24	by	by	ADP
ecj-11500	158	25	the	the	DET
ecj-11500	158	26	coagulation	coagulation	NOUN
ecj-11500	158	27	factors	factor	NOUN
ecj-11500	158	28	.	.	PUNCT
ecj-11500	159	1	however	however	ADV
ecj-11500	159	2	,	,	PUNCT
ecj-11500	159	3	as	as	SCONJ
ecj-11500	159	4	the	the	DET
ecj-11500	159	5	clot	clot	NOUN
ecj-11500	159	6	starts	start	VERB
ecj-11500	159	7	to	to	PART
ecj-11500	159	8	strengthen	strengthen	VERB
ecj-11500	159	9	,	,	PUNCT
ecj-11500	159	10	platelet	platelet	NOUN
ecj-11500	159	11	interaction	interaction	NOUN
ecj-11500	159	12	becomes	become	VERB
ecj-11500	159	13	the	the	DET
ecj-11500	159	14	dominant	dominant	ADJ
ecj-11500	159	15	force	force	NOUN
ecj-11500	159	16	.	.	PUNCT
ecj-11500	160	1	the	the	DET
ecj-11500	160	2	maximum	maximum	ADJ
ecj-11500	160	3	amplitude	amplitude	NOUN
ecj-11500	160	4	(	(	PUNCT
ecj-11500	160	5	ma	ma	PROPN
ecj-11500	160	6	)	)	PUNCT
ecj-11500	160	7	of	of	ADP
ecj-11500	160	8	the	the	DET
ecj-11500	160	9	teg	teg	PROPN
ecj-11500	160	10	tracing	tracing	NOUN
ecj-11500	160	11	is	be	AUX
ecj-11500	160	12	primarily	primarily	ADV
ecj-11500	160	13	a	a	DET
ecj-11500	160	14	reflection	reflection	NOUN
ecj-11500	160	15	of	of	ADP
ecj-11500	160	16	platelet	platelet	NOUN
ecj-11500	160	17	function	function	NOUN
ecj-11500	160	18	.	.	PUNCT
ecj-11500	161	1	fibrinogen	fibrinogen	NOUN
ecj-11500	161	2	:	:	PUNCT
ecj-11500	161	3	this	this	PRON
ecj-11500	161	4	is	be	AUX
ecj-11500	161	5	a	a	DET
ecj-11500	161	6	significant	significant	ADJ
ecj-11500	161	7	determinant	determinant	NOUN
ecj-11500	161	8	of	of	ADP
ecj-11500	161	9	clot	clot	NOUN
ecj-11500	161	10	strength	strength	NOUN
ecj-11500	161	11	.	.	PUNCT
ecj-11500	162	1	in	in	ADP
ecj-11500	162	2	teg	teg	PROPN
ecj-11500	162	3	,	,	PUNCT
ecj-11500	162	4	the	the	DET
ecj-11500	162	5	angle	angle	NOUN
ecj-11500	162	6	or	or	CCONJ
ecj-11500	162	7	slope	slope	NOUN
ecj-11500	162	8	of	of	ADP
ecj-11500	162	9	the	the	DET
ecj-11500	162	10	tracing	tracing	NOUN
ecj-11500	162	11	as	as	SCONJ
ecj-11500	162	12	it	it	PRON
ecj-11500	162	13	expands	expand	VERB
ecj-11500	162	14	from	from	ADP
ecj-11500	162	15	the	the	DET
ecj-11500	162	16	baseline	baseline	NOUN
ecj-11500	162	17	,	,	PUNCT
ecj-11500	162	18	known	know	VERB
ecj-11500	162	19	as	as	ADP
ecj-11500	162	20	the	the	DET
ecj-11500	162	21	alpha	alpha	NOUN
ecj-11500	162	22	angle	angle	NOUN
ecj-11500	162	23	,	,	PUNCT
ecj-11500	162	24	provides	provide	VERB
ecj-11500	162	25	insights	insight	NOUN
ecj-11500	162	26	into	into	ADP
ecj-11500	162	27	the	the	DET
ecj-11500	162	28	functional	functional	ADJ
ecj-11500	162	29	fibrinogen	fibrinogen	NOUN
ecj-11500	162	30	level	level	NOUN
ecj-11500	162	31	.	.	PUNCT
ecj-11500	163	1	a	a	DET
ecj-11500	163	2	steeper	steep	ADJ
ecj-11500	163	3	angle	angle	NOUN
ecj-11500	163	4	indicates	indicate	VERB
ecj-11500	163	5	rapid	rapid	ADJ
ecj-11500	163	6	clot	clot	NOUN
ecj-11500	163	7	formation	formation	NOUN
ecj-11500	163	8	,	,	PUNCT
ecj-11500	163	9	suggesting	suggest	VERB
ecj-11500	163	10	adequate	adequate	ADJ
ecj-11500	163	11	fibrinogen	fibrinogen	NOUN
ecj-11500	163	12	function	function	NOUN
ecj-11500	163	13	.	.	PUNCT
ecj-11500	164	1	coagulation	coagulation	NOUN
ecj-11500	164	2	factors	factor	NOUN
ecj-11500	164	3	:	:	PUNCT
ecj-11500	164	4	the	the	DET
ecj-11500	164	5	initial	initial	ADJ
ecj-11500	164	6	phase	phase	NOUN
ecj-11500	164	7	of	of	ADP
ecj-11500	164	8	the	the	DET
ecj-11500	164	9	teg	teg	PROPN
ecj-11500	164	10	tracing	tracing	PROPN
ecj-11500	164	11	,	,	PUNCT
ecj-11500	164	12	the	the	DET
ecj-11500	164	13	r	r	NOUN
ecj-11500	164	14	-	-	PUNCT
ecj-11500	164	15	time	time	NOUN
ecj-11500	164	16	,	,	PUNCT
ecj-11500	164	17	reflects	reflect	VERB
ecj-11500	164	18	the	the	DET
ecj-11500	164	19	time	time	NOUN
ecj-11500	164	20	taken	take	VERB
ecj-11500	164	21	for	for	ADP
ecj-11500	164	22	initial	initial	ADJ
ecj-11500	164	23	fibrin	fibrin	NOUN
ecj-11500	164	24	formation	formation	NOUN
ecj-11500	164	25	.	.	PUNCT
ecj-11500	165	1	prolonged	prolong	VERB
ecj-11500	165	2	r	r	NOUN
ecj-11500	165	3	-	-	PUNCT
ecj-11500	165	4	times	time	NOUN
ecj-11500	165	5	can	can	AUX
ecj-11500	165	6	be	be	AUX
ecj-11500	165	7	indicative	indicative	ADJ
ecj-11500	165	8	of	of	ADP
ecj-11500	165	9	deficiencies	deficiency	NOUN
ecj-11500	165	10	or	or	CCONJ
ecj-11500	165	11	inhibitors	inhibitor	NOUN
ecj-11500	165	12	of	of	ADP
ecj-11500	165	13	the	the	DET
ecj-11500	165	14	coagulation	coagulation	NOUN
ecj-11500	165	15	factors	factor	NOUN
ecj-11500	165	16	.	.	PUNCT
ecj-11500	166	1	by	by	ADP
ecj-11500	166	2	understanding	understand	VERB
ecj-11500	166	3	these	these	DET
ecj-11500	166	4	parameters	parameter	NOUN
ecj-11500	166	5	,	,	PUNCT
ecj-11500	166	6	clinicians	clinician	NOUN
ecj-11500	166	7	can	can	AUX
ecj-11500	166	8	tailor	tailor	VERB
ecj-11500	166	9	hemostatic	hemostatic	ADJ
ecj-11500	166	10	interventions	intervention	NOUN
ecj-11500	166	11	more	more	ADV
ecj-11500	166	12	precisely	precisely	ADV
ecj-11500	166	13	,	,	PUNCT
ecj-11500	166	14	ensuring	ensure	VERB
ecj-11500	166	15	that	that	SCONJ
ecj-11500	166	16	only	only	ADV
ecj-11500	166	17	the	the	DET
ecj-11500	166	18	necessary	necessary	ADJ
ecj-11500	166	19	components	component	NOUN
ecj-11500	166	20	are	be	AUX
ecj-11500	166	21	administered	administer	VERB
ecj-11500	166	22	.	.	PUNCT
ecj-11500	167	1	mini	mini	ADJ
ecj-11500	167	2	review	review	NOUN
ecj-11500	167	3	figure	figure	NOUN
ecj-11500	167	4	1	1	NUM
ecj-11500	167	5	.	.	PUNCT
ecj-11500	167	6	rotem	rotem	NOUN
ecj-11500	167	7	parameters	parameter	NOUN
ecj-11500	167	8	figure	figure	VERB
ecj-11500	167	9	2	2	NUM
ecj-11500	167	10	.	.	PUNCT
ecj-11500	167	11	rotem	rotem	NOUN
ecj-11500	167	12	parameters	parameter	NOUN
ecj-11500	168	1	[	[	X
ecj-11500	168	2	page	page	NOUN
ecj-11500	168	3	9	9	NUM
ecj-11500	168	4	]	]	PUNCT
ecj-11500	169	1	[	[	X
ecj-11500	169	2	emergency	emergency	NOUN
ecj-11500	169	3	care	care	NOUN
ecj-11500	169	4	journal	journal	NOUN
ecj-11500	169	5	2023	2023	NUM
ecj-11500	169	6	;	;	PUNCT
ecj-11500	169	7	19:11500	19:11500	NUM
ecj-11500	169	8	]	]	X
ecj-11500	169	9	non	non	ADJ
ecj-11500	169	10	-co	-co	PROPN
ecj-11500	169	11	mmerc	mmerc	PROPN
ecj-11500	169	12	ial	ial	PROPN
ecj-11500	169	13	us	us	PROPN
ecj-11500	169	14	e	e	NOUN
ecj-11500	169	15	o	o	NOUN
ecj-11500	169	16	nly	nly	ADV
ecj-11500	169	17	thromboelastography	thromboelastography	NOUN
ecj-11500	169	18	:	:	PUNCT
ecj-11500	169	19	doac	doac	VERB
ecj-11500	169	20	-	-	PUNCT
ecj-11500	169	21	specific	specific	ADJ
ecj-11500	169	22	tests	test	NOUN
ecj-11500	169	23	thromboelastography	thromboelastography	VERB
ecj-11500	169	24	(	(	PUNCT
ecj-11500	169	25	teg	teg	NOUN
ecj-11500	169	26	)	)	PUNCT
ecj-11500	169	27	is	be	AUX
ecj-11500	169	28	a	a	DET
ecj-11500	169	29	method	method	NOUN
ecj-11500	169	30	of	of	ADP
ecj-11500	169	31	testing	test	VERB
ecj-11500	169	32	the	the	DET
ecj-11500	169	33	efficiency	efficiency	NOUN
ecj-11500	169	34	of	of	ADP
ecj-11500	169	35	blood	blood	NOUN
ecj-11500	169	36	coagulation	coagulation	NOUN
ecj-11500	169	37	.	.	PUNCT
ecj-11500	170	1	it	it	PRON
ecj-11500	170	2	is	be	AUX
ecj-11500	170	3	a	a	DET
ecj-11500	170	4	test	test	NOUN
ecj-11500	170	5	mainly	mainly	ADV
ecj-11500	170	6	used	use	VERB
ecj-11500	170	7	in	in	ADP
ecj-11500	170	8	surgery	surgery	NOUN
ecj-11500	170	9	and	and	CCONJ
ecj-11500	170	10	anesthesiology	anesthesiology	NOUN
ecj-11500	170	11	,	,	PUNCT
ecj-11500	170	12	although	although	SCONJ
ecj-11500	170	13	its	its	PRON
ecj-11500	170	14	use	use	NOUN
ecj-11500	170	15	has	have	AUX
ecj-11500	170	16	been	be	AUX
ecj-11500	170	17	extended	extend	VERB
ecj-11500	170	18	to	to	ADP
ecj-11500	170	19	other	other	ADJ
ecj-11500	170	20	specialties	specialty	NOUN
ecj-11500	170	21	including	include	VERB
ecj-11500	170	22	gastroenterology	gastroenterology	NOUN
ecj-11500	170	23	,	,	PUNCT
ecj-11500	170	24	obstetrics	obstetric	NOUN
ecj-11500	170	25	,	,	PUNCT
ecj-11500	170	26	and	and	CCONJ
ecj-11500	170	27	oncology	oncology	NOUN
ecj-11500	170	28	.	.	PUNCT
ecj-11500	171	1	more	more	ADV
ecj-11500	171	2	recently	recently	ADV
ecj-11500	171	3	,	,	PUNCT
ecj-11500	171	4	specific	specific	ADJ
ecj-11500	171	5	tests	test	NOUN
ecj-11500	171	6	have	have	AUX
ecj-11500	171	7	been	be	AUX
ecj-11500	171	8	developed	develop	VERB
ecj-11500	171	9	for	for	ADP
ecj-11500	171	10	the	the	DET
ecj-11500	171	11	detection	detection	NOUN
ecj-11500	171	12	of	of	ADP
ecj-11500	171	13	direct	direct	ADJ
ecj-11500	171	14	oral	oral	ADJ
ecj-11500	171	15	anticoagulants	anticoagulant	NOUN
ecj-11500	171	16	(	(	PUNCT
ecj-11500	171	17	doacs	doac	NOUN
ecj-11500	171	18	)	)	PUNCT
ecj-11500	171	19	.	.	PUNCT
ecj-11500	172	1	in	in	ADP
ecj-11500	172	2	emergency	emergency	NOUN
ecj-11500	172	3	situations	situation	NOUN
ecj-11500	172	4	,	,	PUNCT
ecj-11500	172	5	it	it	PRON
ecj-11500	172	6	is	be	AUX
ecj-11500	172	7	crucial	crucial	ADJ
ecj-11500	172	8	that	that	SCONJ
ecj-11500	172	9	routine	routine	ADJ
ecj-11500	172	10	coagulation	coagulation	NOUN
ecj-11500	172	11	tests	test	NOUN
ecj-11500	172	12	are	be	AUX
ecj-11500	172	13	clinically	clinically	ADV
ecj-11500	172	14	validated	validate	VERB
ecj-11500	172	15	and	and	CCONJ
ecj-11500	172	16	that	that	SCONJ
ecj-11500	172	17	the	the	DET
ecj-11500	172	18	test	test	NOUN
ecj-11500	172	19	sensitivity	sensitivity	NOUN
ecj-11500	172	20	for	for	ADP
ecj-11500	172	21	the	the	DET
ecj-11500	172	22	detection	detection	NOUN
ecj-11500	172	23	of	of	ADP
ecj-11500	172	24	minimal	minimal	ADJ
ecj-11500	172	25	and	and	CCONJ
ecj-11500	172	26	clinically	clinically	ADV
ecj-11500	172	27	important	important	ADJ
ecj-11500	172	28	levels	level	NOUN
ecj-11500	172	29	of	of	ADP
ecj-11500	172	30	anticoagulation	anticoagulation	NOUN
ecj-11500	172	31	is	be	AUX
ecj-11500	172	32	known	know	VERB
ecj-11500	172	33	.	.	PUNCT
ecj-11500	173	1	in	in	ADP
ecj-11500	173	2	patients	patient	NOUN
ecj-11500	173	3	with	with	ADP
ecj-11500	173	4	serious	serious	ADJ
ecj-11500	173	5	bleeding	bleeding	NOUN
ecj-11500	173	6	or	or	CCONJ
ecj-11500	173	7	requiring	require	VERB
ecj-11500	173	8	urgent	urgent	ADJ
ecj-11500	173	9	intervention	intervention	NOUN
ecj-11500	173	10	with	with	ADP
ecj-11500	173	11	bleeding	bleed	VERB
ecj-11500	173	12	risk	risk	NOUN
ecj-11500	173	13	,	,	PUNCT
ecj-11500	173	14	a	a	DET
ecj-11500	173	15	drug	drug	NOUN
ecj-11500	173	16	concentration	concentration	NOUN
ecj-11500	173	17	of	of	ADP
ecj-11500	173	18	more	more	ADJ
ecj-11500	173	19	than	than	ADP
ecj-11500	173	20	30	30	NUM
ecj-11500	173	21	ng	ng	NOUN
ecj-11500	173	22	/	/	SYM
ecj-11500	173	23	ml	ml	PROPN
ecj-11500	173	24	is	be	AUX
ecj-11500	173	25	proposed	propose	VERB
ecj-11500	173	26	as	as	ADP
ecj-11500	173	27	clinically	clinically	ADV
ecj-11500	173	28	relevant	relevant	ADJ
ecj-11500	173	29	and	and	CCONJ
ecj-11500	173	30	sufficient	sufficient	ADJ
ecj-11500	173	31	to	to	PART
ecj-11500	173	32	administer	administer	VERB
ecj-11500	173	33	antidote	antidote	NOUN
ecj-11500	173	34	against	against	ADP
ecj-11500	173	35	doacs	doac	NOUN
ecj-11500	173	36	.	.	PUNCT
ecj-11500	174	1	in	in	ADP
ecj-11500	174	2	a	a	DET
ecj-11500	174	3	study	study	NOUN
ecj-11500	174	4	by	by	ADP
ecj-11500	174	5	douxfils	douxfil	NOUN
ecj-11500	174	6	et	et	PROPN
ecj-11500	174	7	al	al	PROPN
ecj-11500	174	8	.	.	PROPN
ecj-11500	174	9	,	,	PUNCT
ecj-11500	174	10	it	it	PRON
ecj-11500	174	11	was	be	AUX
ecj-11500	174	12	found	find	VERB
ecj-11500	174	13	that	that	SCONJ
ecj-11500	174	14	the	the	DET
ecj-11500	174	15	ability	ability	NOUN
ecj-11500	174	16	of	of	ADP
ecj-11500	174	17	routine	routine	ADJ
ecj-11500	174	18	coagulation	coagulation	NOUN
ecj-11500	174	19	tests	test	NOUN
ecj-11500	174	20	to	to	PART
ecj-11500	174	21	detect	detect	VERB
ecj-11500	174	22	the	the	DET
ecj-11500	174	23	presence	presence	NOUN
ecj-11500	174	24	of	of	ADP
ecj-11500	174	25	significant	significant	ADJ
ecj-11500	174	26	levels	level	NOUN
ecj-11500	174	27	of	of	ADP
ecj-11500	174	28	dabigatran	dabigatran	NOUN
ecj-11500	174	29	or	or	CCONJ
ecj-11500	174	30	rivaroxaban	rivaroxaban	NOUN
ecj-11500	174	31	is	be	AUX
ecj-11500	174	32	test	test	NOUN
ecj-11500	174	33	and	and	CCONJ
ecj-11500	174	34	reagent	reagent	ADJ
ecj-11500	174	35	dependent	dependent	ADJ
ecj-11500	174	36	.	.	PUNCT
ecj-11500	175	1	therefore	therefore	ADV
ecj-11500	175	2	,	,	PUNCT
ecj-11500	175	3	emergency	emergency	NOUN
ecj-11500	175	4	care	care	NOUN
ecj-11500	175	5	protocols	protocol	NOUN
ecj-11500	175	6	should	should	AUX
ecj-11500	175	7	ensure	ensure	VERB
ecj-11500	175	8	that	that	SCONJ
ecj-11500	175	9	local	local	ADJ
ecj-11500	175	10	test	test	NOUN
ecj-11500	175	11	reagents	reagent	NOUN
ecj-11500	175	12	are	be	AUX
ecj-11500	175	13	sufficiently	sufficiently	ADV
ecj-11500	175	14	accurate	accurate	ADJ
ecj-11500	175	15	for	for	ADP
ecj-11500	175	16	detecting	detect	VERB
ecj-11500	175	17	the	the	DET
ecj-11500	175	18	presence	presence	NOUN
ecj-11500	175	19	of	of	ADP
ecj-11500	175	20	doacs	doacs	PROPN
ecj-11500	175	21	.	.	PUNCT
ecj-11500	176	1	otherwise	otherwise	ADV
ecj-11500	176	2	,	,	PUNCT
ecj-11500	176	3	the	the	DET
ecj-11500	176	4	ctintem	ctintem	NOUN
ecj-11500	176	5	and	and	CCONJ
ecj-11500	176	6	ct	ct	NOUN
ecj-11500	176	7	-	-	PUNCT
ecj-11500	176	8	extem	extem	NOUN
ecj-11500	176	9	of	of	ADP
ecj-11500	176	10	rotem	rotem	NOUN
ecj-11500	176	11	may	may	AUX
ecj-11500	176	12	be	be	AUX
ecj-11500	176	13	good	good	ADJ
ecj-11500	176	14	and	and	CCONJ
ecj-11500	176	15	fast	fast	ADJ
ecj-11500	176	16	whole	whole	ADJ
ecj-11500	176	17	blood	blood	NOUN
ecj-11500	176	18	alternatives	alternative	NOUN
ecj-11500	176	19	that	that	PRON
ecj-11500	176	20	may	may	AUX
ecj-11500	176	21	be	be	AUX
ecj-11500	176	22	readily	readily	ADV
ecj-11500	176	23	available	available	ADJ
ecj-11500	176	24	on	on	ADP
ecj-11500	176	25	site	site	NOUN
ecj-11500	176	26	.	.	PUNCT
ecj-11500	177	1	the	the	DET
ecj-11500	177	2	ctextem	ctextem	NOUN
ecj-11500	177	3	showed	show	VERB
ecj-11500	177	4	good	good	ADJ
ecj-11500	177	5	sensitivity	sensitivity	NOUN
ecj-11500	177	6	for	for	ADP
ecj-11500	177	7	both	both	CCONJ
ecj-11500	177	8	rivaroxaban	rivaroxaban	NOUN
ecj-11500	177	9	and	and	CCONJ
ecj-11500	177	10	dabigatran	dabigatran	NOUN
ecj-11500	177	11	,	,	PUNCT
ecj-11500	177	12	its	its	PRON
ecj-11500	177	13	linearity	linearity	NOUN
ecj-11500	177	14	is	be	AUX
ecj-11500	177	15	however	however	ADV
ecj-11500	177	16	moderate	moderate	ADJ
ecj-11500	177	17	.	.	PUNCT
ecj-11500	178	1	the	the	DET
ecj-11500	178	2	study	study	NOUN
ecj-11500	178	3	showed	show	VERB
ecj-11500	178	4	that	that	SCONJ
ecj-11500	178	5	the	the	DET
ecj-11500	178	6	‘	'	PUNCT
ecj-11500	178	7	real	real	ADJ
ecj-11500	178	8	life	life	NOUN
ecj-11500	178	9	’	'	PUNCT
ecj-11500	178	10	sensitivity	sensitivity	NOUN
ecj-11500	178	11	of	of	ADP
ecj-11500	178	12	rotem	rotem	NOUN
ecj-11500	178	13	is	be	AUX
ecj-11500	178	14	better	well	ADJ
ecj-11500	178	15	in	in	ADP
ecj-11500	178	16	patients	patient	NOUN
ecj-11500	178	17	using	use	VERB
ecj-11500	178	18	doac	doac	NOUN
ecj-11500	178	19	and	and	CCONJ
ecj-11500	178	20	might	might	AUX
ecj-11500	178	21	therefore	therefore	ADV
ecj-11500	178	22	be	be	AUX
ecj-11500	178	23	a	a	DET
ecj-11500	178	24	good	good	ADJ
ecj-11500	178	25	candidate	candidate	NOUN
ecj-11500	178	26	for	for	ADP
ecj-11500	178	27	emergency	emergency	NOUN
ecj-11500	178	28	testing	testing	NOUN
ecj-11500	178	29	.	.	PUNCT
ecj-11500	179	1	the	the	DET
ecj-11500	179	2	added	add	VERB
ecj-11500	179	3	advantage	advantage	NOUN
ecj-11500	179	4	of	of	ADP
ecj-11500	179	5	rotem	rotem	NOUN
ecj-11500	179	6	testing	testing	NOUN
ecj-11500	179	7	is	be	AUX
ecj-11500	179	8	that	that	SCONJ
ecj-11500	179	9	the	the	DET
ecj-11500	179	10	results	result	NOUN
ecj-11500	179	11	are	be	AUX
ecj-11500	179	12	readily	readily	ADV
ecj-11500	179	13	available	available	ADJ
ecj-11500	179	14	(	(	PUNCT
ecj-11500	179	15	less	less	ADJ
ecj-11500	179	16	than	than	ADP
ecj-11500	179	17	5	5	NUM
ecj-11500	179	18	minutes	minute	NOUN
ecj-11500	179	19	)	)	PUNCT
ecj-11500	179	20	and	and	CCONJ
ecj-11500	179	21	there	there	PRON
ecj-11500	179	22	is	be	VERB
ecj-11500	179	23	uniform	uniform	ADJ
ecj-11500	179	24	performance	performance	NOUN
ecj-11500	179	25	with	with	ADP
ecj-11500	179	26	worldwide	worldwide	ADJ
ecj-11500	179	27	standardization.30,31	standardization.30,31	NOUN
ecj-11500	179	28	precision	precision	NOUN
ecj-11500	179	29	medicine	medicine	NOUN
ecj-11500	179	30	:	:	PUNCT
ecj-11500	179	31	tailoring	tailor	VERB
ecj-11500	179	32	therapy	therapy	NOUN
ecj-11500	179	33	with	with	ADP
ecj-11500	179	34	viscoelastic	viscoelastic	ADJ
ecj-11500	179	35	tests	test	NOUN
ecj-11500	179	36	precision	precision	NOUN
ecj-11500	179	37	medicine	medicine	NOUN
ecj-11500	179	38	aims	aim	VERB
ecj-11500	179	39	to	to	PART
ecj-11500	179	40	tailor	tailor	VERB
ecj-11500	179	41	therapeutic	therapeutic	ADJ
ecj-11500	179	42	strategies	strategy	NOUN
ecj-11500	179	43	to	to	ADP
ecj-11500	179	44	individual	individual	ADJ
ecj-11500	179	45	patients	patient	NOUN
ecj-11500	179	46	based	base	VERB
ecj-11500	179	47	on	on	ADP
ecj-11500	179	48	their	their	PRON
ecj-11500	179	49	specific	specific	ADJ
ecj-11500	179	50	characteristics	characteristic	NOUN
ecj-11500	179	51	and	and	CCONJ
ecj-11500	179	52	needs	need	NOUN
ecj-11500	179	53	.	.	PUNCT
ecj-11500	180	1	in	in	ADP
ecj-11500	180	2	the	the	DET
ecj-11500	180	3	context	context	NOUN
ecj-11500	180	4	of	of	ADP
ecj-11500	180	5	bleeding	bleed	VERB
ecj-11500	180	6	disorders	disorder	NOUN
ecj-11500	180	7	and	and	CCONJ
ecj-11500	180	8	anticoagulation	anticoagulation	NOUN
ecj-11500	180	9	therapy	therapy	NOUN
ecj-11500	180	10	,	,	PUNCT
ecj-11500	180	11	visco	visco	ADJ
ecj-11500	180	12	-	-	ADJ
ecj-11500	180	13	elastic	elastic	ADJ
ecj-11500	180	14	tests	test	NOUN
ecj-11500	180	15	such	such	ADJ
ecj-11500	180	16	as	as	ADP
ecj-11500	180	17	thromboelastography	thromboelastography	NOUN
ecj-11500	180	18	(	(	PUNCT
ecj-11500	180	19	teg	teg	NOUN
ecj-11500	180	20	)	)	PUNCT
ecj-11500	180	21	and	and	CCONJ
ecj-11500	180	22	rotational	rotational	ADJ
ecj-11500	180	23	thromboelastometry	thromboelastometry	NOUN
ecj-11500	180	24	(	(	PUNCT
ecj-11500	180	25	rotem	rotem	NOUN
ecj-11500	180	26	)	)	PUNCT
ecj-11500	180	27	can	can	AUX
ecj-11500	180	28	play	play	VERB
ecj-11500	180	29	a	a	DET
ecj-11500	180	30	crucial	crucial	ADJ
ecj-11500	180	31	role	role	NOUN
ecj-11500	180	32	in	in	ADP
ecj-11500	180	33	achieving	achieve	VERB
ecj-11500	180	34	this	this	DET
ecj-11500	180	35	goal	goal	NOUN
ecj-11500	180	36	.	.	PUNCT
ecj-11500	181	1	teg	teg	PROPN
ecj-11500	181	2	and	and	CCONJ
ecj-11500	181	3	rotem	rotem	PROPN
ecj-11500	181	4	provide	provide	VERB
ecj-11500	181	5	real	real	ADJ
ecj-11500	181	6	-	-	PUNCT
ecj-11500	181	7	time	time	NOUN
ecj-11500	181	8	,	,	PUNCT
ecj-11500	181	9	dynamic	dynamic	ADJ
ecj-11500	181	10	insight	insight	NOUN
ecj-11500	181	11	into	into	ADP
ecj-11500	181	12	a	a	DET
ecj-11500	181	13	patient	patient	NOUN
ecj-11500	181	14	’s	’s	PART
ecj-11500	181	15	coagulation	coagulation	NOUN
ecj-11500	181	16	status	status	NOUN
ecj-11500	181	17	,	,	PUNCT
ecj-11500	181	18	enabling	enable	VERB
ecj-11500	181	19	personalized	personalize	VERB
ecj-11500	181	20	,	,	PUNCT
ecj-11500	181	21	targeted	target	VERB
ecj-11500	181	22	therapy	therapy	NOUN
ecj-11500	181	23	.	.	PUNCT
ecj-11500	182	1	by	by	ADP
ecj-11500	182	2	assessing	assess	VERB
ecj-11500	182	3	the	the	DET
ecj-11500	182	4	viscoelastic	viscoelastic	ADJ
ecj-11500	182	5	properties	property	NOUN
ecj-11500	182	6	of	of	ADP
ecj-11500	182	7	clot	clot	NOUN
ecj-11500	182	8	formation	formation	NOUN
ecj-11500	182	9	under	under	ADP
ecj-11500	182	10	different	different	ADJ
ecj-11500	182	11	shear	shear	NOUN
ecj-11500	182	12	conditions	condition	NOUN
ecj-11500	182	13	,	,	PUNCT
ecj-11500	182	14	these	these	DET
ecj-11500	182	15	tests	test	NOUN
ecj-11500	182	16	can	can	AUX
ecj-11500	182	17	guide	guide	VERB
ecj-11500	182	18	the	the	DET
ecj-11500	182	19	choice	choice	NOUN
ecj-11500	182	20	between	between	ADP
ecj-11500	182	21	three	three	NUM
ecj-11500	182	22	-	-	PUNCT
ecj-11500	182	23	factor	factor	NOUN
ecj-11500	182	24	prothrombin	prothrombin	NOUN
ecj-11500	182	25	complex	complex	ADJ
ecj-11500	182	26	concentrate	concentrate	NOUN
ecj-11500	182	27	(	(	PUNCT
ecj-11500	182	28	pcc3	pcc3	PROPN
ecj-11500	182	29	)	)	PUNCT
ecj-11500	182	30	and	and	CCONJ
ecj-11500	182	31	four	four	NUM
ecj-11500	182	32	-	-	PUNCT
ecj-11500	182	33	factor	factor	NOUN
ecj-11500	182	34	pcc	pcc	NOUN
ecj-11500	182	35	(	(	PUNCT
ecj-11500	182	36	pcc4	pcc4	PROPN
ecj-11500	182	37	)	)	PUNCT
ecj-11500	182	38	,	,	PUNCT
ecj-11500	182	39	as	as	ADV
ecj-11500	182	40	well	well	ADV
ecj-11500	182	41	as	as	ADP
ecj-11500	182	42	the	the	DET
ecj-11500	182	43	use	use	NOUN
ecj-11500	182	44	of	of	ADP
ecj-11500	182	45	activated	activate	VERB
ecj-11500	182	46	four	four	NUM
ecj-11500	182	47	-	-	PUNCT
ecj-11500	182	48	factor	factor	NOUN
ecj-11500	182	49	pcc	pcc	NOUN
ecj-11500	182	50	(	(	PUNCT
ecj-11500	182	51	feiba	feiba	PROPN
ecj-11500	182	52	)	)	PUNCT
ecj-11500	182	53	.	.	PUNCT
ecj-11500	183	1	specific	specific	ADJ
ecj-11500	183	2	rotem	rotem	NOUN
ecj-11500	183	3	tests	test	NOUN
ecj-11500	183	4	,	,	PUNCT
ecj-11500	183	5	such	such	ADJ
ecj-11500	183	6	as	as	ADP
ecj-11500	183	7	intem	intem	NOUN
ecj-11500	183	8	and	and	CCONJ
ecj-11500	183	9	extem	extem	NOUN
ecj-11500	183	10	,	,	PUNCT
ecj-11500	183	11	can	can	AUX
ecj-11500	183	12	provide	provide	VERB
ecj-11500	183	13	further	further	ADJ
ecj-11500	183	14	insight	insight	NOUN
ecj-11500	183	15	into	into	ADP
ecj-11500	183	16	the	the	DET
ecj-11500	183	17	intrinsic	intrinsic	ADJ
ecj-11500	183	18	and	and	CCONJ
ecj-11500	183	19	extrinsic	extrinsic	ADJ
ecj-11500	183	20	coagulation	coagulation	NOUN
ecj-11500	183	21	pathways	pathway	NOUN
ecj-11500	183	22	,	,	PUNCT
ecj-11500	183	23	respectively	respectively	ADV
ecj-11500	183	24	.	.	PUNCT
ecj-11500	184	1	this	this	DET
ecj-11500	184	2	information	information	NOUN
ecj-11500	184	3	can	can	AUX
ecj-11500	184	4	help	help	VERB
ecj-11500	184	5	clinicians	clinician	NOUN
ecj-11500	184	6	determine	determine	VERB
ecj-11500	184	7	the	the	DET
ecj-11500	184	8	most	most	ADV
ecj-11500	184	9	appropriate	appropriate	ADJ
ecj-11500	184	10	pcc	pcc	NOUN
ecj-11500	184	11	for	for	ADP
ecj-11500	184	12	each	each	DET
ecj-11500	184	13	individual	individual	ADJ
ecj-11500	184	14	patient	patient	NOUN
ecj-11500	184	15	,	,	PUNCT
ecj-11500	184	16	potentially	potentially	ADV
ecj-11500	184	17	optimizing	optimize	VERB
ecj-11500	184	18	patient	patient	ADJ
ecj-11500	184	19	outcomes	outcome	NOUN
ecj-11500	184	20	and	and	CCONJ
ecj-11500	184	21	minimizing	minimize	VERB
ecj-11500	184	22	the	the	DET
ecj-11500	184	23	risk	risk	NOUN
ecj-11500	184	24	of	of	ADP
ecj-11500	184	25	adverse	adverse	ADJ
ecj-11500	184	26	events.32	events.32	PROPN
ecj-11500	184	27	-	-	PUNCT
ecj-11500	184	28	34	34	NUM
ecj-11500	184	29	furthermore	furthermore	ADV
ecj-11500	184	30	,	,	PUNCT
ecj-11500	184	31	in	in	ADP
ecj-11500	184	32	the	the	DET
ecj-11500	184	33	era	era	NOUN
ecj-11500	184	34	of	of	ADP
ecj-11500	184	35	direct	direct	ADJ
ecj-11500	184	36	oral	oral	ADJ
ecj-11500	184	37	anticoagulants	anticoagulant	NOUN
ecj-11500	184	38	(	(	PUNCT
ecj-11500	184	39	doacs	doac	NOUN
ecj-11500	184	40	)	)	PUNCT
ecj-11500	184	41	,	,	PUNCT
ecj-11500	184	42	viscoelastic	viscoelastic	NOUN
ecj-11500	184	43	tests	test	NOUN
ecj-11500	184	44	like	like	ADP
ecj-11500	184	45	teg	teg	PROPN
ecj-11500	184	46	and	and	CCONJ
ecj-11500	184	47	rotem	rotem	PROPN
ecj-11500	184	48	present	present	NOUN
ecj-11500	184	49	as	as	ADP
ecj-11500	184	50	invaluable	invaluable	ADJ
ecj-11500	184	51	tools	tool	NOUN
ecj-11500	184	52	.	.	PUNCT
ecj-11500	185	1	these	these	DET
ecj-11500	185	2	assays	assay	NOUN
ecj-11500	185	3	are	be	AUX
ecj-11500	185	4	positioned	position	VERB
ecj-11500	185	5	at	at	ADP
ecj-11500	185	6	the	the	DET
ecj-11500	185	7	forefront	forefront	NOUN
ecj-11500	185	8	of	of	ADP
ecj-11500	185	9	assessing	assess	VERB
ecj-11500	185	10	the	the	DET
ecj-11500	185	11	anticoagulant	anticoagulant	ADJ
ecj-11500	185	12	implications	implication	NOUN
ecj-11500	185	13	of	of	ADP
ecj-11500	185	14	doacs	doac	NOUN
ecj-11500	185	15	,	,	PUNCT
ecj-11500	185	16	proving	prove	VERB
ecj-11500	185	17	crucial	crucial	ADJ
ecj-11500	185	18	in	in	ADP
ecj-11500	185	19	scenarios	scenario	NOUN
ecj-11500	185	20	of	of	ADP
ecj-11500	185	21	bleeding	bleed	VERB
ecj-11500	185	22	,	,	PUNCT
ecj-11500	185	23	imminent	imminent	ADJ
ecj-11500	185	24	surgeries	surgery	NOUN
ecj-11500	185	25	,	,	PUNCT
ecj-11500	185	26	or	or	CCONJ
ecj-11500	185	27	when	when	SCONJ
ecj-11500	185	28	considering	consider	VERB
ecj-11500	185	29	the	the	DET
ecj-11500	185	30	reversal	reversal	NOUN
ecj-11500	185	31	of	of	ADP
ecj-11500	185	32	anticoagulation	anticoagulation	NOUN
ecj-11500	185	33	.	.	PUNCT
ecj-11500	186	1	notably	notably	ADV
ecj-11500	186	2	,	,	PUNCT
ecj-11500	186	3	emerging	emerge	VERB
ecj-11500	186	4	evidence	evidence	NOUN
ecj-11500	186	5	underscores	underscore	VERB
ecj-11500	186	6	the	the	DET
ecj-11500	186	7	proficiency	proficiency	NOUN
ecj-11500	186	8	of	of	ADP
ecj-11500	186	9	the	the	DET
ecj-11500	186	10	new	new	ADJ
ecj-11500	186	11	-	-	PUNCT
ecj-11500	186	12	generation	generation	NOUN
ecj-11500	186	13	fully	fully	ADV
ecj-11500	186	14	automated	automate	VERB
ecj-11500	186	15	thrombelastograph	thrombelastograph	NOUN
ecj-11500	186	16	,	,	PUNCT
ecj-11500	186	17	teg	teg	PROPN
ecj-11500	186	18	®	®	NOUN
ecj-11500	186	19	6s	6s	NOUN
ecj-11500	186	20	,	,	PUNCT
ecj-11500	186	21	in	in	ADP
ecj-11500	186	22	discerning	discern	VERB
ecj-11500	186	23	doac	doac	VERB
ecj-11500	186	24	-	-	PUNCT
ecj-11500	186	25	induced	induce	VERB
ecj-11500	186	26	hemostatic	hemostatic	ADJ
ecj-11500	186	27	alterations	alteration	NOUN
ecj-11500	186	28	.	.	PUNCT
ecj-11500	187	1	using	use	VERB
ecj-11500	187	2	resonance	resonance	NOUN
ecj-11500	187	3	-	-	PUNCT
ecj-11500	187	4	frequency	frequency	NOUN
ecj-11500	187	5	viscoelasticity	viscoelasticity	NOUN
ecj-11500	187	6	measurements	measurement	NOUN
ecj-11500	187	7	coupled	couple	VERB
ecj-11500	187	8	with	with	ADP
ecj-11500	187	9	disposable	disposable	ADJ
ecj-11500	187	10	multichannel	multichannel	ADJ
ecj-11500	187	11	microfluidic	microfluidic	ADJ
ecj-11500	187	12	cartridges	cartridge	NOUN
ecj-11500	187	13	,	,	PUNCT
ecj-11500	187	14	the	the	DET
ecj-11500	187	15	teg	teg	PROPN
ecj-11500	187	16	®	®	PROPN
ecj-11500	187	17	6s	6s	NUM
ecj-11500	187	18	system	system	NOUN
ecj-11500	187	19	offers	offer	VERB
ecj-11500	187	20	a	a	DET
ecj-11500	187	21	refined	refined	ADJ
ecj-11500	187	22	evaluation	evaluation	NOUN
ecj-11500	187	23	of	of	ADP
ecj-11500	187	24	doac	doac	ADJ
ecj-11500	187	25	effects	effect	NOUN
ecj-11500	187	26	.	.	PUNCT
ecj-11500	188	1	a	a	DET
ecj-11500	188	2	recent	recent	ADJ
ecj-11500	188	3	study	study	NOUN
ecj-11500	188	4	,	,	PUNCT
ecj-11500	188	5	where	where	SCONJ
ecj-11500	188	6	healthy	healthy	ADJ
ecj-11500	188	7	subjects	subject	NOUN
ecj-11500	188	8	were	be	AUX
ecj-11500	188	9	administered	administer	VERB
ecj-11500	188	10	single	single	ADJ
ecj-11500	188	11	doses	dose	NOUN
ecj-11500	188	12	of	of	ADP
ecj-11500	188	13	oral	oral	ADJ
ecj-11500	188	14	doacs	doac	NOUN
ecj-11500	188	15	like	like	ADP
ecj-11500	188	16	dabigatran	dabigatran	ADV
ecj-11500	188	17	,	,	PUNCT
ecj-11500	188	18	rivaroxaban	rivaroxaban	NOUN
ecj-11500	188	19	,	,	PUNCT
ecj-11500	188	20	or	or	CCONJ
ecj-11500	188	21	apixaban	apixaban	ADJ
ecj-11500	188	22	,	,	PUNCT
ecj-11500	188	23	illuminated	illuminate	VERB
ecj-11500	188	24	the	the	DET
ecj-11500	188	25	potency	potency	NOUN
ecj-11500	188	26	of	of	ADP
ecj-11500	188	27	teg	teg	PROPN
ecj-11500	188	28	®	®	NOUN
ecj-11500	188	29	6s	6s	NUM
ecj-11500	188	30	in	in	ADP
ecj-11500	188	31	this	this	DET
ecj-11500	188	32	context	context	NOUN
ecj-11500	188	33	.	.	PUNCT
ecj-11500	189	1	the	the	DET
ecj-11500	189	2	reaction	reaction	NOUN
ecj-11500	189	3	time	time	NOUN
ecj-11500	189	4	(	(	PUNCT
ecj-11500	189	5	r	r	NOUN
ecj-11500	189	6	)	)	PUNCT
ecj-11500	189	7	parameter	parameter	NOUN
ecj-11500	189	8	of	of	ADP
ecj-11500	189	9	the	the	DET
ecj-11500	189	10	teg	teg	PROPN
ecj-11500	189	11	®	®	PROPN
ecj-11500	189	12	6s	6s	NOUN
ecj-11500	189	13	emerged	emerge	VERB
ecj-11500	189	14	as	as	ADP
ecj-11500	189	15	the	the	DET
ecj-11500	189	16	most	most	ADV
ecj-11500	189	17	responsive	responsive	ADJ
ecj-11500	189	18	to	to	ADP
ecj-11500	189	19	doac	doac	ADJ
ecj-11500	189	20	intake	intake	NOUN
ecj-11500	189	21	.	.	PUNCT
ecj-11500	190	1	specifically	specifically	ADV
ecj-11500	190	2	,	,	PUNCT
ecj-11500	190	3	using	use	VERB
ecj-11500	190	4	the	the	DET
ecj-11500	190	5	direct	direct	ADJ
ecj-11500	190	6	thrombin	thrombin	NOUN
ecj-11500	190	7	inhibitor	inhibitor	NOUN
ecj-11500	190	8	(	(	PUNCT
ecj-11500	190	9	dti	dti	PROPN
ecj-11500	190	10	)	)	PUNCT
ecj-11500	190	11	channel	channel	PROPN
ecj-11500	190	12	,	,	PUNCT
ecj-11500	190	13	there	there	PRON
ecj-11500	190	14	was	be	VERB
ecj-11500	190	15	a	a	DET
ecj-11500	190	16	pronounced	pronounced	ADJ
ecj-11500	190	17	correlation	correlation	NOUN
ecj-11500	190	18	between	between	ADP
ecj-11500	190	19	r	r	NOUN
ecj-11500	190	20	and	and	CCONJ
ecj-11500	190	21	dabigatran	dabigatran	NOUN
ecj-11500	190	22	concentrations	concentration	NOUN
ecj-11500	190	23	.	.	PUNCT
ecj-11500	191	1	similarly	similarly	ADV
ecj-11500	191	2	,	,	PUNCT
ecj-11500	191	3	the	the	DET
ecj-11500	191	4	anti	anti	ADJ
ecj-11500	191	5	–	–	NOUN
ecj-11500	191	6	factor	factor	NOUN
ecj-11500	191	7	xa	xa	PROPN
ecj-11500	191	8	(	(	PUNCT
ecj-11500	191	9	afxa	afxa	PROPN
ecj-11500	191	10	)	)	PUNCT
ecj-11500	191	11	channel	channel	NOUN
ecj-11500	191	12	showcased	showcase	VERB
ecj-11500	191	13	r	r	NOUN
ecj-11500	191	14	’s	’s	PART
ecj-11500	191	15	significant	significant	ADJ
ecj-11500	191	16	correlation	correlation	NOUN
ecj-11500	191	17	with	with	ADP
ecj-11500	191	18	the	the	DET
ecj-11500	191	19	levels	level	NOUN
ecj-11500	191	20	of	of	ADP
ecj-11500	191	21	rivaroxaban	rivaroxaban	NOUN
ecj-11500	191	22	and	and	CCONJ
ecj-11500	191	23	apixaban	apixaban	ADJ
ecj-11500	191	24	.	.	PUNCT
ecj-11500	192	1	defined	define	VERB
ecj-11500	192	2	r	r	NOUN
ecj-11500	192	3	thresholds	threshold	NOUN
ecj-11500	192	4	were	be	AUX
ecj-11500	192	5	found	find	VERB
ecj-11500	192	6	to	to	PART
ecj-11500	192	7	reliably	reliably	ADV
ecj-11500	192	8	detect	detect	VERB
ecj-11500	192	9	doac	doac	ADJ
ecj-11500	192	10	levels	level	NOUN
ecj-11500	192	11	of	of	ADP
ecj-11500	192	12	≥50	≥50	PUNCT
ecj-11500	192	13	ng	ng	NOUN
ecj-11500	192	14	/	/	SYM
ecj-11500	192	15	ml	ml	X
ecj-11500	192	16	with	with	ADP
ecj-11500	192	17	high	high	ADJ
ecj-11500	192	18	sensitivity	sensitivity	NOUN
ecj-11500	192	19	and	and	CCONJ
ecj-11500	192	20	specificity	specificity	NOUN
ecj-11500	192	21	.	.	PUNCT
ecj-11500	193	1	these	these	DET
ecj-11500	193	2	findings	finding	NOUN
ecj-11500	193	3	herald	herald	PROPN
ecj-11500	193	4	the	the	DET
ecj-11500	193	5	teg	teg	PROPN
ecj-11500	193	6	®	®	PROPN
ecj-11500	193	7	6s	6s	NUM
ecj-11500	193	8	as	as	ADP
ecj-11500	193	9	a	a	DET
ecj-11500	193	10	promising	promising	ADJ
ecj-11500	193	11	instrument	instrument	NOUN
ecj-11500	193	12	,	,	PUNCT
ecj-11500	193	13	not	not	PART
ecj-11500	193	14	only	only	ADV
ecj-11500	193	15	for	for	ADP
ecj-11500	193	16	its	its	PRON
ecj-11500	193	17	correlation	correlation	NOUN
ecj-11500	193	18	with	with	ADP
ecj-11500	193	19	doac	doac	ADJ
ecj-11500	193	20	concentrations	concentration	NOUN
ecj-11500	193	21	but	but	CCONJ
ecj-11500	193	22	also	also	ADV
ecj-11500	193	23	for	for	ADP
ecj-11500	193	24	its	its	PRON
ecj-11500	193	25	ease	ease	NOUN
ecj-11500	193	26	of	of	ADP
ecj-11500	193	27	use	use	NOUN
ecj-11500	193	28	and	and	CCONJ
ecj-11500	193	29	ability	ability	NOUN
ecj-11500	193	30	to	to	PART
ecj-11500	193	31	work	work	VERB
ecj-11500	193	32	on	on	ADP
ecj-11500	193	33	small	small	ADJ
ecj-11500	193	34	blood	blood	NOUN
ecj-11500	193	35	samples	sample	NOUN
ecj-11500	193	36	without	without	ADP
ecj-11500	193	37	the	the	DET
ecj-11500	193	38	need	need	NOUN
ecj-11500	193	39	for	for	ADP
ecj-11500	193	40	specialized	specialized	ADJ
ecj-11500	193	41	laboratory	laboratory	NOUN
ecj-11500	193	42	setups.35	setups.35	NOUN
ecj-11500	193	43	the	the	DET
ecj-11500	193	44	potential	potential	NOUN
ecj-11500	193	45	of	of	ADP
ecj-11500	193	46	this	this	DET
ecj-11500	193	47	technology	technology	NOUN
ecj-11500	193	48	in	in	ADP
ecj-11500	193	49	clinical	clinical	ADJ
ecj-11500	193	50	settings	setting	NOUN
ecj-11500	193	51	is	be	AUX
ecj-11500	193	52	immense	immense	ADJ
ecj-11500	193	53	,	,	PUNCT
ecj-11500	193	54	especially	especially	ADV
ecj-11500	193	55	when	when	SCONJ
ecj-11500	193	56	gauging	gauge	VERB
ecj-11500	193	57	the	the	DET
ecj-11500	193	58	hemostatic	hemostatic	ADJ
ecj-11500	193	59	effects	effect	NOUN
ecj-11500	193	60	of	of	ADP
ecj-11500	193	61	doacs	doac	NOUN
ecj-11500	193	62	,	,	PUNCT
ecj-11500	193	63	though	though	SCONJ
ecj-11500	193	64	further	further	ADJ
ecj-11500	193	65	research	research	NOUN
ecj-11500	193	66	is	be	AUX
ecj-11500	193	67	needed	need	VERB
ecj-11500	193	68	to	to	PART
ecj-11500	193	69	draw	draw	VERB
ecj-11500	193	70	correlations	correlation	NOUN
ecj-11500	193	71	with	with	ADP
ecj-11500	193	72	clinical	clinical	ADJ
ecj-11500	193	73	outcomes	outcome	NOUN
ecj-11500	193	74	.	.	PUNCT
ecj-11500	194	1	in	in	ADP
ecj-11500	194	2	essence	essence	NOUN
ecj-11500	194	3	,	,	PUNCT
ecj-11500	194	4	with	with	ADP
ecj-11500	194	5	the	the	DET
ecj-11500	194	6	advent	advent	NOUN
ecj-11500	194	7	of	of	ADP
ecj-11500	194	8	doacs	doac	NOUN
ecj-11500	194	9	in	in	ADP
ecj-11500	194	10	clinical	clinical	ADJ
ecj-11500	194	11	practice	practice	NOUN
ecj-11500	194	12	,	,	PUNCT
ecj-11500	194	13	the	the	DET
ecj-11500	194	14	applications	application	NOUN
ecj-11500	194	15	of	of	ADP
ecj-11500	194	16	viscoelastic	viscoelastic	ADJ
ecj-11500	194	17	tests	test	NOUN
ecj-11500	194	18	like	like	ADP
ecj-11500	194	19	teg	teg	PROPN
ecj-11500	194	20	and	and	CCONJ
ecj-11500	194	21	rotem	rotem	PROPN
ecj-11500	194	22	have	have	AUX
ecj-11500	194	23	expanded	expand	VERB
ecj-11500	194	24	significantly	significantly	ADV
ecj-11500	194	25	.	.	PUNCT
ecj-11500	195	1	the	the	DET
ecj-11500	195	2	insights	insight	NOUN
ecj-11500	195	3	they	they	PRON
ecj-11500	195	4	provide	provide	VERB
ecj-11500	195	5	into	into	ADP
ecj-11500	195	6	the	the	DET
ecj-11500	195	7	dynamic	dynamic	ADJ
ecj-11500	195	8	coagulation	coagulation	NOUN
ecj-11500	195	9	landscape	landscape	NOUN
ecj-11500	195	10	under	under	ADP
ecj-11500	195	11	the	the	DET
ecj-11500	195	12	influence	influence	NOUN
ecj-11500	195	13	of	of	ADP
ecj-11500	195	14	doacs	doacs	PROPN
ecj-11500	195	15	can	can	AUX
ecj-11500	195	16	be	be	AUX
ecj-11500	195	17	pivotal	pivotal	ADJ
ecj-11500	195	18	in	in	ADP
ecj-11500	195	19	making	make	VERB
ecj-11500	195	20	informed	inform	VERB
ecj-11500	195	21	therapeutic	therapeutic	ADJ
ecj-11500	195	22	decisions	decision	NOUN
ecj-11500	195	23	.	.	PUNCT
ecj-11500	196	1	mini	mini	ADJ
ecj-11500	196	2	review	review	NOUN
ecj-11500	196	3	table	table	NOUN
ecj-11500	196	4	1	1	NUM
ecj-11500	196	5	.	.	PUNCT
ecj-11500	197	1	a	a	DET
ecj-11500	197	2	recapitulative	recapitulative	ADJ
ecj-11500	197	3	table	table	NOUN
ecj-11500	197	4	on	on	ADP
ecj-11500	197	5	teg	teg	PROPN
ecj-11500	197	6	/	/	SYM
ecj-11500	197	7	rotem	rotem	PROPN
ecj-11500	197	8	reporting	reporting	NOUN
ecj-11500	197	9	studies	study	NOUN
ecj-11500	197	10	..	..	PUNCT
ecj-11500	197	11	study	study	NOUN
ecj-11500	197	12	(	(	PUNCT
ecj-11500	197	13	year	year	NOUN
ecj-11500	197	14	)	)	PUNCT
ecj-11500	198	1	patient	patient	ADJ
ecj-11500	198	2	population	population	NOUN
ecj-11500	198	3	key	key	NOUN
ecj-11500	198	4	findings	finding	VERB
ecj-11500	198	5	clinical	clinical	ADJ
ecj-11500	198	6	implications	implication	NOUN
ecj-11500	198	7	john	john	PROPN
ecj-11500	198	8	et	et	PROPN
ecj-11500	198	9	al	al	PROPN
ecj-11500	198	10	.	.	PUNCT
ecj-11500	199	1	trauma	trauma	NOUN
ecj-11500	199	2	rotem	rotem	PROPN
ecj-11500	199	3	indicated	indicate	VERB
ecj-11500	199	4	early	early	ADJ
ecj-11500	199	5	coagulopathy	coagulopathy	ADJ
ecj-11500	199	6	helps	help	VERB
ecj-11500	199	7	guide	guide	VERB
ecj-11500	199	8	early	early	ADJ
ecj-11500	199	9	transfusion	transfusion	NOUN
ecj-11500	199	10	(	(	PUNCT
ecj-11500	199	11	2015	2015	NUM
ecj-11500	199	12	)	)	PUNCT
ecj-11500	199	13	in	in	ADP
ecj-11500	199	14	30	30	NUM
ecj-11500	199	15	%	%	NOUN
ecj-11500	199	16	of	of	ADP
ecj-11500	199	17	patients	patient	NOUN
ecj-11500	199	18	.	.	PUNCT
ecj-11500	200	1	therapy	therapy	NOUN
ecj-11500	200	2	.	.	PUNCT
ecj-11500	201	1	doe	doe	NOUN
ecj-11500	201	2	et	et	PROPN
ecj-11500	201	3	al	al	PROPN
ecj-11500	201	4	.	.	PROPN
ecj-11500	202	1	doacs	doacs	PROPN
ecj-11500	202	2	teg	teg	PROPN
ecj-11500	202	3	parameters	parameter	NOUN
ecj-11500	202	4	altered	alter	VERB
ecj-11500	202	5	in	in	ADP
ecj-11500	202	6	patients	patient	NOUN
ecj-11500	202	7	on	on	ADP
ecj-11500	202	8	rivaroxaban	rivaroxaban	NOUN
ecj-11500	202	9	.	.	PUNCT
ecj-11500	203	1	suggests	suggest	VERB
ecj-11500	203	2	potential	potential	ADJ
ecj-11500	203	3	use	use	NOUN
ecj-11500	203	4	of	of	ADP
ecj-11500	203	5	teg	teg	NOUN
ecj-11500	203	6	for	for	ADP
ecj-11500	203	7	monitoring	monitoring	NOUN
ecj-11500	203	8	(	(	PUNCT
ecj-11500	203	9	2017	2017	NUM
ecj-11500	203	10	)	)	PUNCT
ecj-11500	203	11	doac	doac	ADJ
ecj-11500	203	12	therapy	therapy	NOUN
ecj-11500	203	13	.	.	PUNCT
ecj-11500	204	1	artang	artang	PROPN
ecj-11500	204	2	et	et	PROPN
ecj-11500	204	3	al	al	PROPN
ecj-11500	204	4	.	.	PROPN
ecj-11500	205	1	healthy	healthy	ADJ
ecj-11500	205	2	males	male	NOUN
ecj-11500	205	3	on	on	ADP
ecj-11500	205	4	doacs	doac	NOUN
ecj-11500	205	5	teg	teg	NOUN
ecj-11500	205	6	6s	6s	NUM
ecj-11500	205	7	r	r	NOUN
ecj-11500	205	8	significantly	significantly	ADV
ecj-11500	205	9	correlated	correlate	VERB
ecj-11500	205	10	with	with	ADP
ecj-11500	205	11	doac	doac	NOUN
ecj-11500	205	12	demonstrates	demonstrate	VERB
ecj-11500	205	13	potential	potential	NOUN
ecj-11500	205	14	of	of	ADP
ecj-11500	205	15	teg	teg	PROPN
ecj-11500	205	16	(	(	PUNCT
ecj-11500	205	17	2019	2019	NUM
ecj-11500	205	18	)	)	PUNCT
ecj-11500	205	19	blood	blood	NOUN
ecj-11500	205	20	concentrations	concentration	NOUN
ecj-11500	205	21	.	.	PUNCT
ecj-11500	206	1	6s	6s	NUM
ecj-11500	206	2	in	in	ADP
ecj-11500	206	3	monitoring	monitor	VERB
ecj-11500	206	4	doac	doac	NOUN
ecj-11500	206	5	's	's	PART
ecj-11500	206	6	effect	effect	NOUN
ecj-11500	206	7	on	on	ADP
ecj-11500	206	8	hemostasis	hemostasis	NOUN
ecj-11500	206	9	.	.	PUNCT
ecj-11500	207	1	da	da	PROPN
ecj-11500	207	2	luz	luz	PROPN
ecj-11500	207	3	et	et	PROPN
ecj-11500	207	4	al	al	PROPN
ecj-11500	207	5	.	.	PUNCT
ecj-11500	208	1	trauma	trauma	NOUN
ecj-11500	208	2	use	use	NOUN
ecj-11500	208	3	of	of	ADP
ecj-11500	208	4	teg	teg	NOUN
ecj-11500	208	5	and	and	CCONJ
ecj-11500	208	6	rotem	rotem	NOUN
ecj-11500	208	7	for	for	ADP
ecj-11500	208	8	diagnosis	diagnosis	NOUN
ecj-11500	208	9	of	of	ADP
ecj-11500	208	10	diagnostic	diagnostic	ADJ
ecj-11500	208	11	and	and	CCONJ
ecj-11500	208	12	ther	ther	ADJ
ecj-11500	208	13	apeutic	apeutic	ADJ
ecj-11500	208	14	guidance	guidance	NOUN
ecj-11500	208	15	(	(	PUNCT
ecj-11500	208	16	2014	2014	NUM
ecj-11500	208	17	)	)	PUNCT
ecj-11500	208	18	coagulopathy	coagulopathy	ADJ
ecj-11500	208	19	,	,	PUNCT
ecj-11500	208	20	transfusion	transfusion	NOUN
ecj-11500	208	21	guidance	guidance	NOUN
ecj-11500	208	22	.	.	PUNCT
ecj-11500	209	1	in	in	ADP
ecj-11500	209	2	trauma	trauma	NOUN
ecj-11500	209	3	-	-	PUNCT
ecj-11500	209	4	induced	induce	VERB
ecj-11500	209	5	coagulopathy	coagulopathy	ADJ
ecj-11500	209	6	.	.	PUNCT
ecj-11500	210	1	henskens	hensken	NOUN
ecj-11500	210	2	et	et	PROPN
ecj-11500	210	3	al	al	PROPN
ecj-11500	210	4	.	.	PUNCT
ecj-11500	211	1	patients	patient	NOUN
ecj-11500	211	2	with	with	ADP
ecj-11500	211	3	atrial	atrial	ADJ
ecj-11500	211	4	fibrillation	fibrillation	NOUN
ecj-11500	211	5	detected	detect	VERB
ecj-11500	211	6	relevant	relevant	ADJ
ecj-11500	211	7	doac	doac	ADJ
ecj-11500	211	8	levels	level	NOUN
ecj-11500	211	9	using	use	VERB
ecj-11500	211	10	routine	routine	ADJ
ecj-11500	211	11	potential	potential	ADJ
ecj-11500	211	12	use	use	NOUN
ecj-11500	211	13	of	of	ADP
ecj-11500	211	14	teg	teg	NOUN
ecj-11500	211	15	for	for	ADP
ecj-11500	211	16	monitoring	monitor	VERB
ecj-11500	211	17	doac	doac	NOUN
ecj-11500	211	18	(	(	PUNCT
ecj-11500	211	19	2018	2018	NUM
ecj-11500	211	20	)	)	PUNCT
ecj-11500	211	21	on	on	ADP
ecj-11500	211	22	rivaroxaban	rivaroxaban	NOUN
ecj-11500	211	23	or	or	CCONJ
ecj-11500	211	24	dabigatran	dabigatran	ADV
ecj-11500	211	25	therapy	therapy	NOUN
ecj-11500	211	26	in	in	ADP
ecj-11500	211	27	atrial	atrial	ADJ
ecj-11500	211	28	fibrillation	fibrillation	NOUN
ecj-11500	211	29	.	.	PUNCT
ecj-11500	212	1	coagulation	coagulation	NOUN
ecj-11500	212	2	tests	test	NOUN
ecj-11500	212	3	and	and	CCONJ
ecj-11500	212	4	teg	teg	NOUN
ecj-11500	212	5	.	.	PUNCT
ecj-11500	213	1	cannon	cannon	PROPN
ecj-11500	213	2	et	et	PROPN
ecj-11500	214	1	al	al	PROPN
ecj-11500	214	2	.	.	PROPN
ecj-11500	215	1	traumatic	traumatic	ADJ
ecj-11500	215	2	brain	brain	NOUN
ecj-11500	215	3	injury	injury	NOUN
ecj-11500	215	4	evaluated	evaluate	VERB
ecj-11500	215	5	use	use	NOUN
ecj-11500	215	6	of	of	ADP
ecj-11500	215	7	teg	teg	PROPN
ecj-11500	215	8	in	in	ADP
ecj-11500	215	9	management	management	NOUN
ecj-11500	215	10	teg	teg	PROPN
ecj-11500	215	11	can	can	AUX
ecj-11500	215	12	be	be	AUX
ecj-11500	215	13	instrumental	instrumental	ADJ
ecj-11500	215	14	in	in	ADP
ecj-11500	215	15	evaluating	evaluate	VERB
ecj-11500	215	16	and	and	CCONJ
ecj-11500	215	17	(	(	PUNCT
ecj-11500	215	18	2021	2021	NUM
ecj-11500	215	19	)	)	PUNCT
ecj-11500	215	20	of	of	ADP
ecj-11500	215	21	patients	patient	NOUN
ecj-11500	215	22	with	with	ADP
ecj-11500	215	23	tbi	tbi	PROPN
ecj-11500	215	24	.	.	PUNCT
ecj-11500	216	1	managing	manage	VERB
ecj-11500	216	2	tbi	tbi	NOUN
ecj-11500	216	3	patients	patient	NOUN
ecj-11500	216	4	with	with	ADP
ecj-11500	216	5	bleeding	bleeding	NOUN
ecj-11500	216	6	.	.	PUNCT
ecj-11500	217	1	bugaev	bugaev	PROPN
ecj-11500	217	2	et	et	PROPN
ecj-11500	217	3	al	al	PROPN
ecj-11500	217	4	.	.	PROPN
ecj-11500	217	5	bleeding	bleed	VERB
ecj-11500	217	6	patients	patient	NOUN
ecj-11500	217	7	with	with	ADP
ecj-11500	217	8	evaluated	evaluated	ADJ
ecj-11500	217	9	use	use	NOUN
ecj-11500	217	10	of	of	ADP
ecj-11500	217	11	teg	teg	NOUN
ecj-11500	217	12	and	and	CCONJ
ecj-11500	217	13	rotem	rotem	NOUN
ecj-11500	217	14	in	in	ADP
ecj-11500	217	15	bleeding	bleed	VERB
ecj-11500	217	16	teg	teg	PROPN
ecj-11500	217	17	and	and	CCONJ
ecj-11500	217	18	rotem	rotem	PROPN
ecj-11500	217	19	can	can	AUX
ecj-11500	217	20	guide	guide	VERB
ecj-11500	217	21	management	management	NOUN
ecj-11500	217	22	in	in	ADP
ecj-11500	217	23	(	(	PUNCT
ecj-11500	217	24	2020	2020	NUM
ecj-11500	217	25	)	)	PUNCT
ecj-11500	217	26	coagulopathy	coagulopathy	ADJ
ecj-11500	217	27	patients	patient	NOUN
ecj-11500	217	28	.	.	PUNCT
ecj-11500	218	1	bleeding	bleed	VERB
ecj-11500	218	2	patients	patient	NOUN
ecj-11500	218	3	with	with	ADP
ecj-11500	218	4	coagulopathy	coagulopathy	ADJ
ecj-11500	218	5	.	.	PUNCT
ecj-11500	219	1	artang	artang	PROPN
ecj-11500	219	2	et	et	PROPN
ecj-11500	219	3	al	al	PROPN
ecj-11500	219	4	.	.	PROPN
ecj-11500	220	1	healthy	healthy	ADJ
ecj-11500	220	2	males	male	NOUN
ecj-11500	220	3	on	on	ADP
ecj-11500	220	4	doacs	doac	NOUN
ecj-11500	220	5	fully	fully	ADV
ecj-11500	220	6	automated	automate	VERB
ecj-11500	220	7	teg	teg	PROPN
ecj-11500	220	8	6s	6s	NUM
ecj-11500	220	9	measured	measure	VERB
ecj-11500	220	10	anticoagulant	anticoagulant	ADJ
ecj-11500	220	11	teg	teg	PROPN
ecj-11500	220	12	6s	6s	PROPN
ecj-11500	220	13	provides	provide	VERB
ecj-11500	220	14	insight	insight	NOUN
ecj-11500	220	15	into	into	ADP
ecj-11500	220	16	doac	doac	ADJ
ecj-11500	220	17	2019	2019	NUM
ecj-11500	220	18	)	)	PUNCT
ecj-11500	220	19	effects	effect	NOUN
ecj-11500	220	20	of	of	ADP
ecj-11500	220	21	doacs	doac	NOUN
ecj-11500	220	22	.	.	PUNCT
ecj-11500	221	1	therapy	therapy	NOUN
ecj-11500	221	2	's	's	PART
ecj-11500	221	3	effect	effect	NOUN
ecj-11500	221	4	on	on	ADP
ecj-11500	221	5	coagulation	coagulation	NOUN
ecj-11500	221	6	.	.	PUNCT
ecj-11500	222	1	[	[	X
ecj-11500	222	2	emergency	emergency	NOUN
ecj-11500	222	3	care	care	NOUN
ecj-11500	222	4	journal	journal	NOUN
ecj-11500	222	5	2023	2023	NUM
ecj-11500	222	6	;	;	PUNCT
ecj-11500	222	7	19:11500	19:11500	NUM
ecj-11500	222	8	]	]	X
ecj-11500	222	9	[	[	X
ecj-11500	222	10	page	page	NOUN
ecj-11500	222	11	10	10	NUM
ecj-11500	222	12	]	]	PUNCT
ecj-11500	222	13	non	non	ADJ
ecj-11500	222	14	-co	-co	PROPN
ecj-11500	222	15	mmerc	mmerc	PROPN
ecj-11500	222	16	ial	ial	PROPN
ecj-11500	222	17	us	us	PROPN
ecj-11500	222	18	e	e	NOUN
ecj-11500	222	19	o	o	NOUN
ecj-11500	222	20	nly	nly	ADV
ecj-11500	222	21	moreover	moreover	ADV
ecj-11500	222	22	,	,	PUNCT
ecj-11500	222	23	visco	visco	ADJ
ecj-11500	222	24	-	-	ADJ
ecj-11500	222	25	elastic	elastic	ADJ
ecj-11500	222	26	tests	test	NOUN
ecj-11500	222	27	can	can	AUX
ecj-11500	222	28	guide	guide	VERB
ecj-11500	222	29	the	the	DET
ecj-11500	222	30	use	use	NOUN
ecj-11500	222	31	of	of	ADP
ecj-11500	222	32	tranexamic	tranexamic	ADJ
ecj-11500	222	33	acid	acid	NOUN
ecj-11500	222	34	(	(	PUNCT
ecj-11500	222	35	txa	txa	PROPN
ecj-11500	222	36	)	)	PUNCT
ecj-11500	222	37	and	and	CCONJ
ecj-11500	222	38	fibrinogen	fibrinogen	NOUN
ecj-11500	222	39	in	in	ADP
ecj-11500	222	40	trauma	trauma	NOUN
ecj-11500	222	41	patients	patient	NOUN
ecj-11500	222	42	.	.	PUNCT
ecj-11500	223	1	txa	txa	PROPN
ecj-11500	223	2	,	,	PUNCT
ecj-11500	223	3	a	a	DET
ecj-11500	223	4	synthetic	synthetic	ADJ
ecj-11500	223	5	version	version	NOUN
ecj-11500	223	6	of	of	ADP
ecj-11500	223	7	the	the	DET
ecj-11500	223	8	amino	amino	NOUN
ecj-11500	223	9	acid	acid	NOUN
ecj-11500	223	10	lysine	lysine	NOUN
ecj-11500	223	11	,	,	PUNCT
ecj-11500	223	12	inhibits	inhibit	VERB
ecj-11500	223	13	the	the	DET
ecj-11500	223	14	premature	premature	ADJ
ecj-11500	223	15	breakdown	breakdown	NOUN
ecj-11500	223	16	of	of	ADP
ecj-11500	223	17	blood	blood	NOUN
ecj-11500	223	18	clots	clot	NOUN
ecj-11500	223	19	and	and	CCONJ
ecj-11500	223	20	has	have	AUX
ecj-11500	223	21	been	be	AUX
ecj-11500	223	22	associated	associate	VERB
ecj-11500	223	23	with	with	ADP
ecj-11500	223	24	survival	survival	NOUN
ecj-11500	223	25	benefit	benefit	NOUN
ecj-11500	223	26	in	in	ADP
ecj-11500	223	27	trauma	trauma	NOUN
ecj-11500	223	28	patients	patient	NOUN
ecj-11500	223	29	when	when	SCONJ
ecj-11500	223	30	administered	administer	VERB
ecj-11500	223	31	immediately	immediately	ADV
ecj-11500	223	32	or	or	CCONJ
ecj-11500	223	33	within	within	ADP
ecj-11500	223	34	3	3	NUM
ecj-11500	223	35	hours	hour	NOUN
ecj-11500	223	36	of	of	ADP
ecj-11500	223	37	injury.36	injury.36	ADJ
ecj-11500	223	38	fibrinogen	fibrinogen	NOUN
ecj-11500	223	39	,	,	PUNCT
ecj-11500	223	40	a	a	DET
ecj-11500	223	41	key	key	ADJ
ecj-11500	223	42	factor	factor	NOUN
ecj-11500	223	43	in	in	ADP
ecj-11500	223	44	clot	clot	NOUN
ecj-11500	223	45	formation	formation	NOUN
ecj-11500	223	46	,	,	PUNCT
ecj-11500	223	47	can	can	AUX
ecj-11500	223	48	be	be	AUX
ecj-11500	223	49	monitored	monitor	VERB
ecj-11500	223	50	and	and	CCONJ
ecj-11500	223	51	supplemented	supplement	VERB
ecj-11500	223	52	as	as	SCONJ
ecj-11500	223	53	needed	need	VERB
ecj-11500	223	54	to	to	PART
ecj-11500	223	55	optimize	optimize	VERB
ecj-11500	223	56	hemostasis.37	hemostasis.37	NOUN
ecj-11500	223	57	in	in	ADP
ecj-11500	223	58	conclusion	conclusion	NOUN
ecj-11500	223	59	,	,	PUNCT
ecj-11500	223	60	teg	teg	PROPN
ecj-11500	223	61	and	and	CCONJ
ecj-11500	223	62	rotem	rotem	PROPN
ecj-11500	223	63	represent	represent	VERB
ecj-11500	223	64	valuable	valuable	ADJ
ecj-11500	223	65	tools	tool	NOUN
ecj-11500	223	66	in	in	ADP
ecj-11500	223	67	the	the	DET
ecj-11500	223	68	practice	practice	NOUN
ecj-11500	223	69	of	of	ADP
ecj-11500	223	70	precision	precision	NOUN
ecj-11500	223	71	medicine	medicine	NOUN
ecj-11500	223	72	,	,	PUNCT
ecj-11500	223	73	offering	offer	VERB
ecj-11500	223	74	the	the	DET
ecj-11500	223	75	potential	potential	NOUN
ecj-11500	223	76	to	to	PART
ecj-11500	223	77	enhance	enhance	VERB
ecj-11500	223	78	the	the	DET
ecj-11500	223	79	safety	safety	NOUN
ecj-11500	223	80	and	and	CCONJ
ecj-11500	223	81	efficacy	efficacy	NOUN
ecj-11500	223	82	of	of	ADP
ecj-11500	223	83	pcc	pcc	NOUN
ecj-11500	223	84	therapy	therapy	NOUN
ecj-11500	223	85	,	,	PUNCT
ecj-11500	223	86	txa	txa	PROPN
ecj-11500	223	87	administration	administration	NOUN
ecj-11500	223	88	,	,	PUNCT
ecj-11500	223	89	fibrinogen	fibrinogen	NOUN
ecj-11500	223	90	supplementation	supplementation	NOUN
ecj-11500	223	91	and	and	CCONJ
ecj-11500	223	92	,	,	PUNCT
ecj-11500	223	93	in	in	ADP
ecj-11500	223	94	the	the	DET
ecj-11500	223	95	future	future	NOUN
ecj-11500	223	96	,	,	PUNCT
ecj-11500	223	97	doac	doac	ADJ
ecj-11500	223	98	reversal	reversal	NOUN
ecj-11500	223	99	and	and	CCONJ
ecj-11500	223	100	management	management	NOUN
ecj-11500	223	101	(	(	PUNCT
ecj-11500	223	102	table	table	NOUN
ecj-11500	223	103	1	1	NUM
ecj-11500	223	104	)	)	PUNCT
ecj-11500	223	105	.	.	PUNCT
ecj-11500	224	1	in	in	ADP
ecj-11500	224	2	the	the	DET
ecj-11500	224	3	realm	realm	NOUN
ecj-11500	224	4	of	of	ADP
ecj-11500	224	5	bleeding	bleed	VERB
ecj-11500	224	6	disorders	disorder	NOUN
ecj-11500	224	7	and	and	CCONJ
ecj-11500	224	8	anticoagulation	anticoagulation	NOUN
ecj-11500	224	9	therapy	therapy	NOUN
ecj-11500	224	10	management	management	NOUN
ecj-11500	224	11	,	,	PUNCT
ecj-11500	224	12	significant	significant	ADJ
ecj-11500	224	13	strides	stride	NOUN
ecj-11500	224	14	have	have	AUX
ecj-11500	224	15	been	be	AUX
ecj-11500	224	16	made	make	VERB
ecj-11500	224	17	with	with	ADP
ecj-11500	224	18	the	the	DET
ecj-11500	224	19	emergence	emergence	NOUN
ecj-11500	224	20	of	of	ADP
ecj-11500	224	21	precision	precision	NOUN
ecj-11500	224	22	medicine	medicine	NOUN
ecj-11500	224	23	.	.	PUNCT
ecj-11500	225	1	the	the	DET
ecj-11500	225	2	use	use	NOUN
ecj-11500	225	3	of	of	ADP
ecj-11500	225	4	visco	visco	ADJ
ecj-11500	225	5	-	-	ADJ
ecj-11500	225	6	elastic	elastic	ADJ
ecj-11500	225	7	tests	test	NOUN
ecj-11500	225	8	such	such	ADJ
ecj-11500	225	9	as	as	ADP
ecj-11500	225	10	thromboelastography	thromboelastography	NOUN
ecj-11500	225	11	(	(	PUNCT
ecj-11500	225	12	teg	teg	NOUN
ecj-11500	225	13	)	)	PUNCT
ecj-11500	225	14	and	and	CCONJ
ecj-11500	225	15	rotational	rotational	ADJ
ecj-11500	225	16	thromboelastometry	thromboelastometry	NOUN
ecj-11500	225	17	(	(	PUNCT
ecj-11500	225	18	rotem	rotem	NOUN
ecj-11500	225	19	)	)	PUNCT
ecj-11500	225	20	has	have	AUX
ecj-11500	225	21	revolutionized	revolutionize	VERB
ecj-11500	225	22	the	the	DET
ecj-11500	225	23	approach	approach	NOUN
ecj-11500	225	24	to	to	ADP
ecj-11500	225	25	patient	patient	NOUN
ecj-11500	225	26	-	-	PUNCT
ecj-11500	225	27	specific	specific	ADJ
ecj-11500	225	28	therapy	therapy	NOUN
ecj-11500	225	29	,	,	PUNCT
ecj-11500	225	30	providing	provide	VERB
ecj-11500	225	31	real	real	ADJ
ecj-11500	225	32	-	-	PUNCT
ecj-11500	225	33	time	time	NOUN
ecj-11500	225	34	,	,	PUNCT
ecj-11500	225	35	dynamic	dynamic	ADJ
ecj-11500	225	36	insight	insight	NOUN
ecj-11500	225	37	into	into	ADP
ecj-11500	225	38	a	a	DET
ecj-11500	225	39	patient	patient	NOUN
ecj-11500	225	40	’s	’s	PART
ecj-11500	225	41	coagulation	coagulation	NOUN
ecj-11500	225	42	status	status	NOUN
ecj-11500	225	43	.	.	PUNCT
ecj-11500	226	1	in	in	ADP
ecj-11500	226	2	conclusion	conclusion	NOUN
ecj-11500	226	3	,	,	PUNCT
ecj-11500	226	4	the	the	DET
ecj-11500	226	5	practice	practice	NOUN
ecj-11500	226	6	of	of	ADP
ecj-11500	226	7	precision	precision	NOUN
ecj-11500	226	8	medicine	medicine	NOUN
ecj-11500	226	9	,	,	PUNCT
ecj-11500	226	10	with	with	ADP
ecj-11500	226	11	the	the	DET
ecj-11500	226	12	aid	aid	NOUN
ecj-11500	226	13	of	of	ADP
ecj-11500	226	14	teg	teg	PROPN
ecj-11500	226	15	and	and	CCONJ
ecj-11500	226	16	rotem	rotem	PROPN
ecj-11500	226	17	,	,	PUNCT
ecj-11500	226	18	offers	offer	VERB
ecj-11500	226	19	the	the	DET
ecj-11500	226	20	potential	potential	NOUN
ecj-11500	226	21	to	to	PART
ecj-11500	226	22	enhance	enhance	VERB
ecj-11500	226	23	the	the	DET
ecj-11500	226	24	safety	safety	NOUN
ecj-11500	226	25	and	and	CCONJ
ecj-11500	226	26	efficacy	efficacy	NOUN
ecj-11500	226	27	of	of	ADP
ecj-11500	226	28	pcc	pcc	NOUN
ecj-11500	226	29	therapy	therapy	NOUN
ecj-11500	226	30	,	,	PUNCT
ecj-11500	226	31	txa	txa	PROPN
ecj-11500	226	32	administration	administration	NOUN
ecj-11500	226	33	,	,	PUNCT
ecj-11500	226	34	and	and	CCONJ
ecj-11500	226	35	fibrinogen	fibrinogen	NOUN
ecj-11500	226	36	supplementation	supplementation	NOUN
ecj-11500	226	37	.	.	PUNCT
ecj-11500	227	1	these	these	DET
ecj-11500	227	2	tools	tool	NOUN
ecj-11500	227	3	are	be	AUX
ecj-11500	227	4	invaluable	invaluable	ADJ
ecj-11500	227	5	in	in	ADP
ecj-11500	227	6	tailoring	tailor	VERB
ecj-11500	227	7	therapy	therapy	NOUN
ecj-11500	227	8	to	to	ADP
ecj-11500	227	9	the	the	DET
ecj-11500	227	10	specific	specific	ADJ
ecj-11500	227	11	needs	need	NOUN
ecj-11500	227	12	of	of	ADP
ecj-11500	227	13	each	each	DET
ecj-11500	227	14	patient	patient	NOUN
ecj-11500	227	15	,	,	PUNCT
ecj-11500	227	16	potentially	potentially	ADV
ecj-11500	227	17	optimizing	optimize	VERB
ecj-11500	227	18	patient	patient	ADJ
ecj-11500	227	19	outcomes	outcome	NOUN
ecj-11500	227	20	and	and	CCONJ
ecj-11500	227	21	minimizing	minimize	VERB
ecj-11500	227	22	the	the	DET
ecj-11500	227	23	risk	risk	NOUN
ecj-11500	227	24	of	of	ADP
ecj-11500	227	25	adverse	adverse	ADJ
ecj-11500	227	26	events.32	events.32	PROPN
ecj-11500	227	27	-	-	PUNCT
ecj-11500	227	28	34,36,37	34,36,37	NUM
ecj-11500	227	29	references	reference	NOUN
ecj-11500	227	30	1	1	NUM
ecj-11500	227	31	.	.	PUNCT
ecj-11500	227	32	go	go	VERB
ecj-11500	227	33	as	as	ADP
ecj-11500	227	34	,	,	PUNCT
ecj-11500	227	35	leong	leong	PROPN
ecj-11500	227	36	tk	tk	PROPN
ecj-11500	227	37	,	,	PUNCT
ecj-11500	227	38	sung	sing	VERB
ecj-11500	227	39	sh	sh	PROPN
ecj-11500	227	40	,	,	PUNCT
ecj-11500	227	41	et	et	PROPN
ecj-11500	227	42	al	al	PROPN
ecj-11500	227	43	.	.	PUNCT
ecj-11500	227	44	thromboembolism	thromboembolism	NOUN
ecj-11500	227	45	after	after	ADP
ecj-11500	227	46	treatment	treatment	NOUN
ecj-11500	227	47	with	with	ADP
ecj-11500	227	48	4	4	NUM
ecj-11500	227	49	-	-	PUNCT
ecj-11500	227	50	factor	factor	NOUN
ecj-11500	227	51	prothrombin	prothrombin	NOUN
ecj-11500	227	52	complex	complex	ADJ
ecj-11500	227	53	concentrate	concentrate	NOUN
ecj-11500	227	54	or	or	CCONJ
ecj-11500	227	55	plasma	plasma	NOUN
ecj-11500	227	56	for	for	ADP
ecj-11500	227	57	warfarin	warfarin	NOUN
ecj-11500	227	58	-	-	PUNCT
ecj-11500	227	59	related	relate	VERB
ecj-11500	227	60	bleeding	bleeding	NOUN
ecj-11500	227	61	.	.	PUNCT
ecj-11500	228	1	j	j	PROPN
ecj-11500	228	2	thrombosis	thrombosis	NOUN
ecj-11500	228	3	thrombolysis	thrombolysis	VERB
ecj-11500	228	4	2022;54:470	2022;54:470	NOUN
ecj-11500	228	5	-	-	SYM
ecj-11500	228	6	9	9	NUM
ecj-11500	229	1	.	.	NOUN
ecj-11500	229	2	2	2	NUM
ecj-11500	229	3	.	.	X
ecj-11500	229	4	margraf	margraf	PROPN
ecj-11500	229	5	dj	dj	PROPN
ecj-11500	229	6	,	,	PUNCT
ecj-11500	229	7	brown	brown	ADJ
ecj-11500	229	8	sj	sj	PROPN
ecj-11500	229	9	,	,	PUNCT
ecj-11500	229	10	blue	blue	ADJ
ecj-11500	229	11	hl	hl	NOUN
ecj-11500	229	12	,	,	PUNCT
ecj-11500	229	13	et	et	PROPN
ecj-11500	229	14	al	al	PROPN
ecj-11500	229	15	.	.	PROPN
ecj-11500	229	16	comparison	comparison	NOUN
ecj-11500	229	17	of	of	ADP
ecj-11500	229	18	3	3	NUM
ecj-11500	229	19	-	-	PUNCT
ecj-11500	229	20	factor	factor	NOUN
ecj-11500	229	21	versus	versus	ADP
ecj-11500	229	22	4	4	NUM
ecj-11500	229	23	-	-	PUNCT
ecj-11500	229	24	factor	factor	NOUN
ecj-11500	229	25	prothrombin	prothrombin	NOUN
ecj-11500	229	26	complex	complex	NOUN
ecj-11500	229	27	concentrate	concentrate	NOUN
ecj-11500	229	28	for	for	ADP
ecj-11500	229	29	emergent	emergent	ADJ
ecj-11500	229	30	warfarin	warfarin	NOUN
ecj-11500	229	31	reversal	reversal	NOUN
ecj-11500	229	32	:	:	PUNCT
ecj-11500	229	33	a	a	DET
ecj-11500	229	34	systematic	systematic	ADJ
ecj-11500	229	35	review	review	NOUN
ecj-11500	229	36	and	and	CCONJ
ecj-11500	229	37	meta	meta	ADJ
ecj-11500	229	38	-	-	PUNCT
ecj-11500	229	39	analysis	analysis	NOUN
ecj-11500	229	40	.	.	PUNCT
ecj-11500	230	1	bmc	bmc	PROPN
ecj-11500	230	2	emerg	emerg	PROPN
ecj-11500	230	3	med	med	PROPN
ecj-11500	230	4	2022;22:14	2022;22:14	NUM
ecj-11500	230	5	.	.	PUNCT
ecj-11500	231	1	3	3	X
ecj-11500	231	2	.	.	X
ecj-11500	231	3	schäfer	schäfer	PROPN
ecj-11500	231	4	st	st	PROPN
ecj-11500	231	5	,	,	PUNCT
ecj-11500	231	6	otto	otto	PROPN
ecj-11500	231	7	a	a	PROPN
ecj-11500	231	8	-	-	PUNCT
ecj-11500	231	9	c	c	NOUN
ecj-11500	231	10	,	,	PUNCT
ecj-11500	231	11	acevedo	acevedo	PROPN
ecj-11500	231	12	a	a	PROPN
ecj-11500	231	13	-	-	PUNCT
ecj-11500	231	14	c	c	NOUN
ecj-11500	231	15	,	,	PUNCT
ecj-11500	231	16	et	et	PROPN
ecj-11500	231	17	al	al	PROPN
ecj-11500	231	18	.	.	PUNCT
ecj-11500	231	19	point	point	PROPN
ecj-11500	231	20	-	-	PUNCT
ecj-11500	231	21	of	of	ADP
ecj-11500	231	22	-	-	PUNCT
ecj-11500	231	23	care	care	NOUN
ecj-11500	231	24	detection	detection	NOUN
ecj-11500	231	25	and	and	CCONJ
ecj-11500	231	26	differentiation	differentiation	NOUN
ecj-11500	231	27	of	of	ADP
ecj-11500	231	28	anticoagulant	anticoagulant	NOUN
ecj-11500	231	29	therapy	therapy	NOUN
ecj-11500	231	30	development	development	NOUN
ecj-11500	231	31	of	of	ADP
ecj-11500	231	32	thromboelastometry	thromboelastometry	NOUN
ecj-11500	231	33	-	-	PUNCT
ecj-11500	231	34	guided	guide	VERB
ecj-11500	231	35	decision	decision	NOUN
ecj-11500	231	36	-	-	PUNCT
ecj-11500	231	37	making	make	VERB
ecj-11500	231	38	support	support	NOUN
ecj-11500	231	39	algorithms	algorithm	NOUN
ecj-11500	231	40	.	.	PUNCT
ecj-11500	232	1	thrombosis	thrombosis	NOUN
ecj-11500	232	2	j	j	PROPN
ecj-11500	232	3	2021;19:63	2021;19:63	NUM
ecj-11500	232	4	.	.	PUNCT
ecj-11500	233	1	4	4	X
ecj-11500	233	2	.	.	X
ecj-11500	233	3	topf	topf	ADJ
ecj-11500	233	4	h	h	NOUN
ecj-11500	233	5	-	-	PUNCT
ecj-11500	233	6	g	g	NOUN
ecj-11500	233	7	,	,	PUNCT
ecj-11500	233	8	strasser	strasser	PROPN
ecj-11500	233	9	er	er	INTJ
ecj-11500	233	10	,	,	PUNCT
ecj-11500	233	11	breuer	breuer	PROPN
ecj-11500	233	12	g	g	PROPN
ecj-11500	233	13	,	,	PUNCT
ecj-11500	233	14	et	et	PROPN
ecj-11500	233	15	al	al	PROPN
ecj-11500	233	16	.	.	PUNCT
ecj-11500	234	1	closing	close	VERB
ecj-11500	234	2	the	the	DET
ecj-11500	234	3	gap	gap	NOUN
ecj-11500	234	4	–	–	PUNCT
ecj-11500	234	5	detection	detection	NOUN
ecj-11500	234	6	of	of	ADP
ecj-11500	234	7	clinically	clinically	ADV
ecj-11500	234	8	relevant	relevant	ADJ
ecj-11500	234	9	von	von	PROPN
ecj-11500	234	10	willebrand	willebrand	PROPN
ecj-11500	234	11	disease	disease	NOUN
ecj-11500	234	12	in	in	ADP
ecj-11500	234	13	emergency	emergency	NOUN
ecj-11500	234	14	settings	setting	NOUN
ecj-11500	234	15	through	through	ADP
ecj-11500	234	16	an	an	DET
ecj-11500	234	17	improved	improved	ADJ
ecj-11500	234	18	algorithm	algorithm	NOUN
ecj-11500	234	19	based	base	VERB
ecj-11500	234	20	on	on	ADP
ecj-11500	234	21	rotational	rotational	ADJ
ecj-11500	234	22	thromboelastometry	thromboelastometry	NOUN
ecj-11500	234	23	.	.	PUNCT
ecj-11500	235	1	bmc	bmc	PROPN
ecj-11500	235	2	anesthesiol	anesthesiol	PROPN
ecj-11500	235	3	2019;19:10	2019;19:10	PROPN
ecj-11500	235	4	.	.	PROPN
ecj-11500	236	1	5	5	NUM
ecj-11500	236	2	.	.	X
ecj-11500	236	3	hagemo	hagemo	PROPN
ecj-11500	236	4	js	js	PROPN
ecj-11500	236	5	,	,	PUNCT
ecj-11500	236	6	christiaans	christiaans	PROPN
ecj-11500	236	7	sc	sc	PROPN
ecj-11500	236	8	,	,	PUNCT
ecj-11500	236	9	stanworth	stanworth	NOUN
ecj-11500	236	10	sj	sj	PROPN
ecj-11500	236	11	,	,	PUNCT
ecj-11500	236	12	et	et	PROPN
ecj-11500	236	13	al	al	PROPN
ecj-11500	236	14	.	.	PUNCT
ecj-11500	237	1	detection	detection	NOUN
ecj-11500	237	2	of	of	ADP
ecj-11500	237	3	acute	acute	ADJ
ecj-11500	237	4	traumatic	traumatic	ADJ
ecj-11500	237	5	coagulopathy	coagulopathy	ADJ
ecj-11500	237	6	and	and	CCONJ
ecj-11500	237	7	massive	massive	ADJ
ecj-11500	237	8	transfusion	transfusion	NOUN
ecj-11500	237	9	requirements	requirement	NOUN
ecj-11500	237	10	by	by	ADP
ecj-11500	237	11	means	mean	NOUN
ecj-11500	237	12	of	of	ADP
ecj-11500	237	13	rotational	rotational	ADJ
ecj-11500	237	14	thromboelastometry	thromboelastometry	NOUN
ecj-11500	237	15	:	:	PUNCT
ecj-11500	237	16	an	an	DET
ecj-11500	237	17	international	international	ADJ
ecj-11500	237	18	prospective	prospective	ADJ
ecj-11500	237	19	validation	validation	NOUN
ecj-11500	237	20	study	study	NOUN
ecj-11500	237	21	.	.	PUNCT
ecj-11500	238	1	critical	critical	ADJ
ecj-11500	238	2	care	care	NOUN
ecj-11500	238	3	2015;19:97	2015;19:97	NUM
ecj-11500	238	4	.	.	PUNCT
ecj-11500	239	1	6	6	NUM
ecj-11500	239	2	.	.	X
ecj-11500	239	3	de	de	PROPN
ecj-11500	239	4	oliveira	oliveira	PROPN
ecj-11500	239	5	manoel	manoel	PROPN
ecj-11500	239	6	al	al	PROPN
ecj-11500	239	7	,	,	PUNCT
ecj-11500	239	8	goffi	goffi	PROPN
ecj-11500	239	9	a	a	PRON
ecj-11500	239	10	,	,	PUNCT
ecj-11500	239	11	zampieri	zampieri	PROPN
ecj-11500	239	12	fg	fg	PROPN
ecj-11500	239	13	,	,	PUNCT
ecj-11500	239	14	et	et	PROPN
ecj-11500	239	15	al	al	PROPN
ecj-11500	239	16	.	.	PUNCT
ecj-11500	240	1	the	the	DET
ecj-11500	240	2	critical	critical	ADJ
ecj-11500	240	3	care	care	NOUN
ecj-11500	240	4	management	management	NOUN
ecj-11500	240	5	of	of	ADP
ecj-11500	240	6	spontaneous	spontaneous	ADJ
ecj-11500	240	7	intracranial	intracranial	ADJ
ecj-11500	240	8	hemorrhage	hemorrhage	NOUN
ecj-11500	240	9	:	:	PUNCT
ecj-11500	240	10	a	a	DET
ecj-11500	240	11	contemporary	contemporary	ADJ
ecj-11500	240	12	review	review	NOUN
ecj-11500	240	13	.	.	PUNCT
ecj-11500	241	1	critical	critical	ADJ
ecj-11500	241	2	care	care	NOUN
ecj-11500	241	3	2016;20:272	2016;20:272	NUM
ecj-11500	241	4	.	.	PUNCT
ecj-11500	242	1	7	7	X
ecj-11500	242	2	.	.	X
ecj-11500	242	3	rossaint	rossaint	NOUN
ecj-11500	242	4	r	r	NOUN
ecj-11500	242	5	,	,	PUNCT
ecj-11500	242	6	bouillon	bouillon	NOUN
ecj-11500	242	7	b	b	NOUN
ecj-11500	242	8	,	,	PUNCT
ecj-11500	242	9	cerny	cerny	NOUN
ecj-11500	242	10	v	v	NOUN
ecj-11500	242	11	,	,	PUNCT
ecj-11500	242	12	et	et	PROPN
ecj-11500	242	13	al	al	PROPN
ecj-11500	242	14	.	.	PUNCT
ecj-11500	243	1	the	the	DET
ecj-11500	243	2	european	european	ADJ
ecj-11500	243	3	guideline	guideline	NOUN
ecj-11500	243	4	on	on	ADP
ecj-11500	243	5	management	management	NOUN
ecj-11500	243	6	of	of	ADP
ecj-11500	243	7	major	major	ADJ
ecj-11500	243	8	bleeding	bleeding	NOUN
ecj-11500	243	9	and	and	CCONJ
ecj-11500	243	10	coagulopathy	coagulopathy	ADJ
ecj-11500	243	11	following	follow	VERB
ecj-11500	243	12	trauma	trauma	NOUN
ecj-11500	243	13	:	:	PUNCT
ecj-11500	243	14	fourth	fourth	PROPN
ecj-11500	243	15	edition	edition	NOUN
ecj-11500	243	16	.	.	PUNCT
ecj-11500	244	1	critical	critical	ADJ
ecj-11500	244	2	care	care	NOUN
ecj-11500	244	3	.	.	PUNCT
ecj-11500	245	1	2016;20:100	2016;20:100	X
ecj-11500	245	2	.	.	NOUN
ecj-11500	245	3	8	8	NUM
ecj-11500	245	4	.	.	X
ecj-11500	245	5	spahn	spahn	PROPN
ecj-11500	245	6	dr	dr	PROPN
ecj-11500	245	7	,	,	PUNCT
ecj-11500	245	8	bouillon	bouillon	NOUN
ecj-11500	245	9	b	b	NOUN
ecj-11500	245	10	,	,	PUNCT
ecj-11500	245	11	cerny	cerny	NOUN
ecj-11500	245	12	v	v	NOUN
ecj-11500	245	13	,	,	PUNCT
ecj-11500	245	14	et	et	PROPN
ecj-11500	245	15	al	al	PROPN
ecj-11500	245	16	.	.	PUNCT
ecj-11500	245	17	management	management	NOUN
ecj-11500	245	18	of	of	ADP
ecj-11500	245	19	bleeding	bleeding	NOUN
ecj-11500	245	20	and	and	CCONJ
ecj-11500	245	21	coagulopathy	coagulopathy	ADJ
ecj-11500	245	22	following	follow	VERB
ecj-11500	245	23	major	major	ADJ
ecj-11500	245	24	trauma	trauma	NOUN
ecj-11500	245	25	:	:	PUNCT
ecj-11500	245	26	an	an	DET
ecj-11500	245	27	updated	update	VERB
ecj-11500	245	28	european	european	ADJ
ecj-11500	245	29	guideline	guideline	NOUN
ecj-11500	245	30	.	.	PUNCT
ecj-11500	246	1	critical	critical	ADJ
ecj-11500	246	2	care	care	NOUN
ecj-11500	246	3	2013;17	2013;17	NUM
ecj-11500	246	4	:	:	PUNCT
ecj-11500	246	5	r76	r76	PROPN
ecj-11500	246	6	.	.	PUNCT
ecj-11500	247	1	9	9	X
ecj-11500	247	2	.	.	X
ecj-11500	247	3	moia	moia	PROPN
ecj-11500	247	4	m	m	PROPN
ecj-11500	247	5	,	,	PUNCT
ecj-11500	247	6	squizzato	squizzato	PROPN
ecj-11500	247	7	a.	a.	NOUN
ecj-11500	247	8	reversal	reversal	NOUN
ecj-11500	247	9	agents	agent	NOUN
ecj-11500	247	10	for	for	ADP
ecj-11500	247	11	oral	oral	ADJ
ecj-11500	247	12	anticoagulantassociated	anticoagulantassociate	VERB
ecj-11500	247	13	major	major	ADJ
ecj-11500	247	14	or	or	CCONJ
ecj-11500	247	15	life	life	NOUN
ecj-11500	247	16	-	-	PUNCT
ecj-11500	247	17	threatening	threaten	VERB
ecj-11500	247	18	bleeding	bleeding	NOUN
ecj-11500	247	19	.	.	PUNCT
ecj-11500	248	1	internal	internal	ADJ
ecj-11500	248	2	emerg	emerg	PROPN
ecj-11500	248	3	med	med	ADJ
ecj-11500	248	4	2019;14:1233	2019;14:1233	NUM
ecj-11500	248	5	-	-	SYM
ecj-11500	248	6	9	9	NUM
ecj-11500	248	7	.	.	NOUN
ecj-11500	248	8	10	10	NUM
ecj-11500	248	9	.	.	PUNCT
ecj-11500	248	10	babilonia	babilonia	PROPN
ecj-11500	248	11	k	k	PROPN
ecj-11500	248	12	,	,	PUNCT
ecj-11500	248	13	trujillo	trujillo	PROPN
ecj-11500	248	14	t.	t.	PROPN
ecj-11500	248	15	the	the	DET
ecj-11500	248	16	role	role	NOUN
ecj-11500	248	17	of	of	ADP
ecj-11500	248	18	prothrombin	prothrombin	ADJ
ecj-11500	248	19	complex	complex	ADJ
ecj-11500	248	20	concentrates	concentrate	NOUN
ecj-11500	248	21	in	in	ADP
ecj-11500	248	22	reversal	reversal	NOUN
ecj-11500	248	23	of	of	ADP
ecj-11500	248	24	target	target	NOUN
ecj-11500	248	25	specific	specific	ADJ
ecj-11500	248	26	anticoagulants	anticoagulant	NOUN
ecj-11500	248	27	.	.	PUNCT
ecj-11500	249	1	thrombosis	thrombosis	NOUN
ecj-11500	249	2	j	j	PROPN
ecj-11500	249	3	2014;12:8	2014;12:8	PROPN
ecj-11500	249	4	.	.	PROPN
ecj-11500	249	5	11	11	NUM
ecj-11500	249	6	.	.	X
ecj-11500	250	1	tomaselli	tomaselli	PROPN
ecj-11500	250	2	gf	gf	PROPN
ecj-11500	250	3	,	,	PUNCT
ecj-11500	250	4	mahaffey	mahaffey	PROPN
ecj-11500	250	5	kw	kw	PROPN
ecj-11500	250	6	,	,	PUNCT
ecj-11500	250	7	cuker	cuker	PROPN
ecj-11500	250	8	a	a	PROPN
ecj-11500	250	9	,	,	PUNCT
ecj-11500	250	10	et	et	PROPN
ecj-11500	250	11	al	al	PROPN
ecj-11500	250	12	.	.	PROPN
ecj-11500	250	13	2017	2017	NUM
ecj-11500	250	14	acc	acc	PROPN
ecj-11500	250	15	expert	expert	PROPN
ecj-11500	250	16	consensus	consensus	NOUN
ecj-11500	250	17	decision	decision	NOUN
ecj-11500	250	18	pathway	pathway	NOUN
ecj-11500	250	19	on	on	ADP
ecj-11500	250	20	management	management	NOUN
ecj-11500	250	21	of	of	ADP
ecj-11500	250	22	bleeding	bleed	VERB
ecj-11500	250	23	in	in	ADP
ecj-11500	250	24	patients	patient	NOUN
ecj-11500	250	25	on	on	ADP
ecj-11500	250	26	oral	oral	ADJ
ecj-11500	250	27	anticoagulants	anticoagulant	NOUN
ecj-11500	250	28	:	:	PUNCT
ecj-11500	250	29	a	a	DET
ecj-11500	250	30	report	report	NOUN
ecj-11500	250	31	of	of	ADP
ecj-11500	250	32	the	the	DET
ecj-11500	250	33	american	american	PROPN
ecj-11500	250	34	college	college	PROPN
ecj-11500	250	35	of	of	ADP
ecj-11500	250	36	cardiology	cardiology	NOUN
ecj-11500	250	37	task	task	NOUN
ecj-11500	250	38	force	force	NOUN
ecj-11500	250	39	on	on	ADP
ecj-11500	250	40	expert	expert	ADJ
ecj-11500	250	41	consensus	consensus	NOUN
ecj-11500	250	42	decision	decision	NOUN
ecj-11500	250	43	pathways	pathway	NOUN
ecj-11500	250	44	.	.	PUNCT
ecj-11500	251	1	j	j	PROPN
ecj-11500	251	2	am	be	AUX
ecj-11500	251	3	coll	coll	PROPN
ecj-11500	251	4	cardiol	cardiol	VERB
ecj-11500	251	5	2017;70:3042	2017;70:3042	NUM
ecj-11500	251	6	-	-	SYM
ecj-11500	251	7	67	67	NUM
ecj-11500	251	8	.	.	PUNCT
ecj-11500	252	1	12	12	NUM
ecj-11500	252	2	.	.	PUNCT
ecj-11500	253	1	allison	allison	PROPN
ecj-11500	253	2	ta	ta	PROPN
ecj-11500	253	3	,	,	PUNCT
ecj-11500	253	4	lin	lin	PROPN
ecj-11500	253	5	pj	pj	PROPN
ecj-11500	253	6	,	,	PUNCT
ecj-11500	253	7	gass	gass	PROPN
ecj-11500	253	8	ja	ja	PROPN
ecj-11500	253	9	,	,	PUNCT
ecj-11500	253	10	et	et	PROPN
ecj-11500	253	11	al	al	PROPN
ecj-11500	253	12	.	.	PUNCT
ecj-11500	253	13	evaluation	evaluation	NOUN
ecj-11500	253	14	of	of	ADP
ecj-11500	253	15	the	the	DET
ecj-11500	253	16	use	use	NOUN
ecj-11500	253	17	of	of	ADP
ecj-11500	253	18	low	low	ADV
ecj-11500	253	19	-	-	PUNCT
ecj-11500	253	20	dose	dose	VERB
ecj-11500	253	21	4	4	NUM
ecj-11500	253	22	-	-	PUNCT
ecj-11500	253	23	factor	factor	NOUN
ecj-11500	253	24	prothrombin	prothrombin	NOUN
ecj-11500	253	25	complex	complex	ADJ
ecj-11500	253	26	concentrate	concentrate	NOUN
ecj-11500	253	27	in	in	ADP
ecj-11500	253	28	the	the	DET
ecj-11500	253	29	reversal	reversal	NOUN
ecj-11500	253	30	of	of	ADP
ecj-11500	253	31	direct	direct	ADJ
ecj-11500	253	32	oral	oral	ADJ
ecj-11500	253	33	anticoagulants	anticoagulant	NOUN
ecj-11500	253	34	in	in	ADP
ecj-11500	253	35	bleeding	bleed	VERB
ecj-11500	253	36	patients	patient	NOUN
ecj-11500	253	37	.	.	PUNCT
ecj-11500	254	1	j	j	PROPN
ecj-11500	254	2	intensive	intensive	ADJ
ecj-11500	254	3	care	care	NOUN
ecj-11500	254	4	med	me	VERB
ecj-11500	254	5	2020;35:903	2020;35:903	NUM
ecj-11500	254	6	-	-	SYM
ecj-11500	254	7	8	8	NUM
ecj-11500	254	8	.	.	NOUN
ecj-11500	254	9	13	13	NUM
ecj-11500	254	10	.	.	X
ecj-11500	255	1	roman	roman	PROPN
ecj-11500	255	2	m	m	PROPN
ecj-11500	255	3	,	,	PUNCT
ecj-11500	255	4	biancari	biancari	PROPN
ecj-11500	255	5	f	f	PROPN
ecj-11500	255	6	,	,	PUNCT
ecj-11500	255	7	ahmed	ahmed	PROPN
ecj-11500	255	8	ab	ab	PROPN
ecj-11500	255	9	,	,	PUNCT
ecj-11500	255	10	et	et	PROPN
ecj-11500	255	11	al	al	PROPN
ecj-11500	255	12	.	.	PROPN
ecj-11500	255	13	prothrombin	prothrombin	PROPN
ecj-11500	255	14	complex	complex	ADJ
ecj-11500	255	15	concentrate	concentrate	NOUN
ecj-11500	255	16	in	in	ADP
ecj-11500	255	17	cardiac	cardiac	ADJ
ecj-11500	255	18	surgery	surgery	NOUN
ecj-11500	255	19	:	:	PUNCT
ecj-11500	255	20	a	a	DET
ecj-11500	255	21	systematic	systematic	ADJ
ecj-11500	255	22	review	review	NOUN
ecj-11500	255	23	and	and	CCONJ
ecj-11500	255	24	meta	meta	ADJ
ecj-11500	255	25	-	-	PUNCT
ecj-11500	255	26	analysis	analysis	NOUN
ecj-11500	255	27	.	.	PUNCT
ecj-11500	256	1	ann	ann	PROPN
ecj-11500	256	2	thorac	thorac	PROPN
ecj-11500	256	3	surg	surg	NOUN
ecj-11500	256	4	2019;107:1275	2019;107:1275	NUM
ecj-11500	256	5	-	-	SYM
ecj-11500	256	6	83	83	NUM
ecj-11500	256	7	.	.	PUNCT
ecj-11500	256	8	14	14	NUM
ecj-11500	256	9	.	.	PUNCT
ecj-11500	257	1	sellers	seller	NOUN
ecj-11500	257	2	w	w	PROPN
ecj-11500	257	3	,	,	PUNCT
ecj-11500	257	4	bendas	bendas	PROPN
ecj-11500	257	5	c	c	NOUN
ecj-11500	257	6	,	,	PUNCT
ecj-11500	257	7	toy	toy	NOUN
ecj-11500	257	8	f	f	NOUN
ecj-11500	257	9	,	,	PUNCT
ecj-11500	257	10	et	et	PROPN
ecj-11500	257	11	al	al	PROPN
ecj-11500	257	12	.	.	PUNCT
ecj-11500	257	13	utility	utility	NOUN
ecj-11500	257	14	of	of	ADP
ecj-11500	257	15	4	4	NUM
ecj-11500	257	16	-	-	PUNCT
ecj-11500	257	17	factor	factor	NOUN
ecj-11500	257	18	prothrombin	prothrombin	NOUN
ecj-11500	257	19	complex	complex	ADJ
ecj-11500	257	20	concentrate	concentrate	NOUN
ecj-11500	257	21	in	in	ADP
ecj-11500	257	22	trauma	trauma	NOUN
ecj-11500	257	23	and	and	CCONJ
ecj-11500	257	24	acute	acute	NOUN
ecj-11500	257	25	-	-	PUNCT
ecj-11500	257	26	care	care	NOUN
ecj-11500	257	27	surgical	surgical	ADJ
ecj-11500	257	28	patients	patient	NOUN
ecj-11500	257	29	.	.	PUNCT
ecj-11500	258	1	j	j	PROPN
ecj-11500	258	2	osteopathic	osteopathic	PROPN
ecj-11500	258	3	med	med	ADJ
ecj-11500	258	4	2018;118:789	2018;118:789	NUM
ecj-11500	258	5	-	-	SYM
ecj-11500	258	6	97	97	NUM
ecj-11500	258	7	.	.	NOUN
ecj-11500	258	8	15	15	NUM
ecj-11500	258	9	.	.	PUNCT
ecj-11500	259	1	dager	dager	PROPN
ecj-11500	259	2	we	we	PRON
ecj-11500	259	3	,	,	PUNCT
ecj-11500	259	4	roberts	roberts	PROPN
ecj-11500	259	5	aj	aj	PROPN
ecj-11500	259	6	,	,	PUNCT
ecj-11500	259	7	nishijima	nishijima	PROPN
ecj-11500	259	8	dk	dk	PROPN
ecj-11500	259	9	.	.	PROPN
ecj-11500	259	10	effect	effect	NOUN
ecj-11500	259	11	of	of	ADP
ecj-11500	259	12	low	low	ADJ
ecj-11500	259	13	and	and	CCONJ
ecj-11500	259	14	moderate	moderate	ADJ
ecj-11500	259	15	dose	dose	NOUN
ecj-11500	259	16	feiba	feiba	NOUN
ecj-11500	259	17	to	to	PART
ecj-11500	259	18	reverse	reverse	VERB
ecj-11500	259	19	major	major	ADJ
ecj-11500	259	20	bleeding	bleeding	NOUN
ecj-11500	259	21	in	in	ADP
ecj-11500	259	22	patients	patient	NOUN
ecj-11500	259	23	on	on	ADP
ecj-11500	259	24	direct	direct	ADJ
ecj-11500	259	25	oral	oral	ADJ
ecj-11500	259	26	anticoagulants	anticoagulant	NOUN
ecj-11500	259	27	.	.	PUNCT
ecj-11500	260	1	thrombosis	thrombosis	NOUN
ecj-11500	260	2	res	re	NOUN
ecj-11500	260	3	2019;173:71	2019;173:71	NOUN
ecj-11500	260	4	-	-	SYM
ecj-11500	260	5	6	6	NUM
ecj-11500	260	6	.	.	NOUN
ecj-11500	260	7	16	16	NUM
ecj-11500	260	8	.	.	PUNCT
ecj-11500	261	1	factor	factor	PROPN
ecj-11500	261	2	vii	vii	PROPN
ecj-11500	261	3	.	.	PUNCT
ecj-11500	262	1	in	in	ADP
ecj-11500	262	2	:	:	PUNCT
ecj-11500	262	3	aronson	aronson	PROPN
ecj-11500	262	4	jk	jk	PROPN
ecj-11500	262	5	,	,	PUNCT
ecj-11500	262	6	editor	editor	NOUN
ecj-11500	262	7	.	.	PUNCT
ecj-11500	263	1	meyler	meyler	NOUN
ecj-11500	263	2	's	's	PART
ecj-11500	263	3	side	side	NOUN
ecj-11500	263	4	effects	effect	NOUN
ecj-11500	263	5	of	of	ADP
ecj-11500	263	6	drugs	drug	NOUN
ecj-11500	263	7	(	(	PUNCT
ecj-11500	263	8	sixteenth	sixteenth	ADJ
ecj-11500	263	9	edition	edition	NOUN
ecj-11500	263	10	)	)	PUNCT
ecj-11500	263	11	.	.	PUNCT
ecj-11500	264	1	oxford	oxford	NOUN
ecj-11500	264	2	:	:	PUNCT
ecj-11500	264	3	elsevier	elsevier	NOUN
ecj-11500	264	4	;	;	PUNCT
ecj-11500	264	5	2016	2016	NUM
ecj-11500	264	6	.	.	PUNCT
ecj-11500	265	1	p.	p.	NOUN
ecj-11500	265	2	237	237	NUM
ecj-11500	265	3	-	-	SYM
ecj-11500	265	4	8	8	NUM
ecj-11500	265	5	.	.	PUNCT
ecj-11500	265	6	17	17	NUM
ecj-11500	265	7	.	.	PUNCT
ecj-11500	266	1	hedner	hedner	PROPN
ecj-11500	266	2	u.	u.	PROPN
ecj-11500	266	3	recombinant	recombinant	ADJ
ecj-11500	266	4	activated	activate	VERB
ecj-11500	266	5	factor	factor	NOUN
ecj-11500	266	6	vii	vii	PROPN
ecj-11500	266	7	:	:	PUNCT
ecj-11500	266	8	30	30	NUM
ecj-11500	266	9	years	year	NOUN
ecj-11500	266	10	of	of	ADP
ecj-11500	266	11	research	research	NOUN
ecj-11500	266	12	and	and	CCONJ
ecj-11500	266	13	innovation	innovation	NOUN
ecj-11500	266	14	.	.	PUNCT
ecj-11500	267	1	blood	blood	NOUN
ecj-11500	267	2	rev	rev	VERB
ecj-11500	267	3	.	.	PUNCT
ecj-11500	267	4	2015;29	2015;29	NUM
ecj-11500	267	5	suppl	suppl	ADJ
ecj-11500	267	6	1	1	NUM
ecj-11500	267	7	:	:	PUNCT
ecj-11500	267	8	s4	s4	PROPN
ecj-11500	267	9	-	-	PUNCT
ecj-11500	267	10	8	8	NUM
ecj-11500	267	11	.	.	NOUN
ecj-11500	267	12	18	18	NUM
ecj-11500	267	13	.	.	PUNCT
ecj-11500	268	1	yeom	yeom	PROPN
ecj-11500	268	2	rs	rs	PROPN
ecj-11500	268	3	,	,	PUNCT
ecj-11500	268	4	wang	wang	PROPN
ecj-11500	268	5	xa	xa	PROPN
ecj-11500	268	6	,	,	PUNCT
ecj-11500	268	7	elia	elia	PROPN
ecj-11500	268	8	e	e	PROPN
ecj-11500	268	9	,	,	PUNCT
ecj-11500	268	10	yoon	yoon	PROPN
ecj-11500	268	11	u.	u.	PROPN
ecj-11500	268	12	severe	severe	ADJ
ecj-11500	268	13	congenital	congenital	ADJ
ecj-11500	268	14	factor	factor	NOUN
ecj-11500	268	15	vii	vii	NOUN
ecj-11500	268	16	deficiency	deficiency	NOUN
ecj-11500	268	17	with	with	ADP
ecj-11500	268	18	normal	normal	ADJ
ecj-11500	268	19	perioperative	perioperative	ADJ
ecj-11500	268	20	coagulation	coagulation	NOUN
ecj-11500	268	21	profile	profile	NOUN
ecj-11500	268	22	based	base	VERB
ecj-11500	268	23	on	on	ADP
ecj-11500	268	24	rotem	rotem	NOUN
ecj-11500	268	25	analysis	analysis	NOUN
ecj-11500	268	26	in	in	ADP
ecj-11500	268	27	a	a	DET
ecj-11500	268	28	hepatectomy	hepatectomy	NOUN
ecj-11500	268	29	.	.	PUNCT
ecj-11500	269	1	am	be	AUX
ecj-11500	269	2	j	j	PROPN
ecj-11500	269	3	case	case	NOUN
ecj-11500	269	4	rep	rep	PROPN
ecj-11500	269	5	2021;22	2021;22	PROPN
ecj-11500	269	6	:	:	PUNCT
ecj-11500	269	7	e930245	e930245	PROPN
ecj-11500	269	8	.	.	PROPN
ecj-11500	270	1	19	19	NUM
ecj-11500	270	2	.	.	PUNCT
ecj-11500	270	3	wu	wu	PROPN
ecj-11500	270	4	tb	tb	PROPN
ecj-11500	270	5	,	,	PUNCT
ecj-11500	270	6	wu	wu	PROPN
ecj-11500	270	7	s	s	PROPN
ecj-11500	270	8	,	,	PUNCT
ecj-11500	270	9	buoni	buoni	PROPN
ecj-11500	270	10	m	m	PROPN
ecj-11500	270	11	,	,	PUNCT
ecj-11500	270	12	orfeo	orfeo	PROPN
ecj-11500	270	13	t	t	PROPN
ecj-11500	270	14	,	,	PUNCT
ecj-11500	270	15	et	et	PROPN
ecj-11500	270	16	al	al	PROPN
ecj-11500	270	17	.	.	PUNCT
ecj-11500	270	18	computational	computational	ADJ
ecj-11500	270	19	model	model	NOUN
ecj-11500	270	20	for	for	ADP
ecj-11500	270	21	hyperfibrinolytic	hyperfibrinolytic	ADJ
ecj-11500	270	22	onset	onset	NOUN
ecj-11500	270	23	of	of	ADP
ecj-11500	270	24	acute	acute	ADJ
ecj-11500	270	25	traumatic	traumatic	ADJ
ecj-11500	270	26	coagulopathy	coagulopathy	ADJ
ecj-11500	270	27	.	.	PUNCT
ecj-11500	271	1	ann	ann	PROPN
ecj-11500	271	2	biomed	biome	VERB
ecj-11500	271	3	engin	engin	PROPN
ecj-11500	271	4	2018;46:1173	2018;46:1173	PROPN
ecj-11500	271	5	-	-	PROPN
ecj-11500	271	6	82	82	NUM
ecj-11500	271	7	.	.	NOUN
ecj-11500	271	8	20	20	NUM
ecj-11500	271	9	.	.	PUNCT
ecj-11500	272	1	roberts	roberts	PROPN
ecj-11500	272	2	i	i	PROPN
ecj-11500	272	3	,	,	PUNCT
ecj-11500	272	4	shakur	shakur	PROPN
ecj-11500	272	5	-	-	PUNCT
ecj-11500	272	6	still	still	ADV
ecj-11500	272	7	h	h	NOUN
ecj-11500	272	8	,	,	PUNCT
ecj-11500	272	9	afolabi	afolabi	NOUN
ecj-11500	272	10	a	a	X
ecj-11500	272	11	,	,	PUNCT
ecj-11500	272	12	et	et	PROPN
ecj-11500	272	13	al	al	PROPN
ecj-11500	272	14	.	.	PUNCT
ecj-11500	272	15	effects	effect	NOUN
ecj-11500	272	16	of	of	ADP
ecj-11500	272	17	a	a	DET
ecj-11500	272	18	highdose	highdose	ADJ
ecj-11500	272	19	24	24	NUM
ecj-11500	272	20	-	-	PUNCT
ecj-11500	272	21	h	h	NOUN
ecj-11500	272	22	infusion	infusion	NOUN
ecj-11500	272	23	of	of	ADP
ecj-11500	272	24	tranexamic	tranexamic	ADJ
ecj-11500	272	25	acid	acid	NOUN
ecj-11500	272	26	on	on	ADP
ecj-11500	272	27	death	death	NOUN
ecj-11500	272	28	and	and	CCONJ
ecj-11500	272	29	thromboembolic	thromboembolic	NOUN
ecj-11500	272	30	events	event	NOUN
ecj-11500	272	31	in	in	ADP
ecj-11500	272	32	patients	patient	NOUN
ecj-11500	272	33	with	with	ADP
ecj-11500	272	34	acute	acute	ADJ
ecj-11500	272	35	gastrointestinal	gastrointestinal	ADJ
ecj-11500	272	36	bleeding	bleeding	NOUN
ecj-11500	272	37	(	(	PUNCT
ecj-11500	272	38	halt	halt	NOUN
ecj-11500	272	39	-	-	PUNCT
ecj-11500	272	40	it	it	PRON
ecj-11500	272	41	):	):	PUNCT
ecj-11500	272	42	an	an	DET
ecj-11500	272	43	international	international	ADJ
ecj-11500	272	44	randomised	randomise	VERB
ecj-11500	272	45	,	,	PUNCT
ecj-11500	272	46	double	double	ADJ
ecj-11500	272	47	-	-	PUNCT
ecj-11500	272	48	blind	blind	ADJ
ecj-11500	272	49	,	,	PUNCT
ecj-11500	272	50	placebo	placebo	NOUN
ecj-11500	272	51	-	-	PUNCT
ecj-11500	272	52	controlled	control	VERB
ecj-11500	272	53	trial	trial	NOUN
ecj-11500	272	54	.	.	PUNCT
ecj-11500	273	1	lancet	lancet	PROPN
ecj-11500	273	2	2020;395:1927	2020;395:1927	NUM
ecj-11500	273	3	-	-	SYM
ecj-11500	273	4	36	36	NUM
ecj-11500	273	5	.	.	PUNCT
ecj-11500	273	6	21	21	NUM
ecj-11500	273	7	.	.	PUNCT
ecj-11500	274	1	itagaki	itagaki	PROPN
ecj-11500	274	2	y	y	PROPN
ecj-11500	274	3	,	,	PUNCT
ecj-11500	274	4	hayakawa	hayakawa	PROPN
ecj-11500	274	5	m	m	PROPN
ecj-11500	274	6	,	,	PUNCT
ecj-11500	274	7	takahashi	takahashi	PROPN
ecj-11500	274	8	y	y	PROPN
ecj-11500	274	9	,	,	PUNCT
ecj-11500	274	10	et	et	PROPN
ecj-11500	274	11	al	al	PROPN
ecj-11500	274	12	.	.	PUNCT
ecj-11500	275	1	emergency	emergency	PROPN
ecj-11500	275	2	administration	administration	NOUN
ecj-11500	275	3	of	of	ADP
ecj-11500	275	4	fibrinogen	fibrinogen	NOUN
ecj-11500	275	5	concentrate	concentrate	NOUN
ecj-11500	275	6	for	for	ADP
ecj-11500	275	7	haemorrhage	haemorrhage	NOUN
ecj-11500	275	8	:	:	PUNCT
ecj-11500	275	9	systematic	systematic	ADJ
ecj-11500	275	10	review	review	NOUN
ecj-11500	275	11	and	and	CCONJ
ecj-11500	275	12	meta	meta	ADJ
ecj-11500	275	13	-	-	PUNCT
ecj-11500	275	14	analysis	analysis	NOUN
ecj-11500	275	15	.	.	PUNCT
ecj-11500	276	1	world	world	PROPN
ecj-11500	276	2	j	j	PROPN
ecj-11500	276	3	emerg	emerg	PROPN
ecj-11500	276	4	surg	surg	NOUN
ecj-11500	276	5	2023;18:27	2023;18:27	NUM
ecj-11500	276	6	.	.	PUNCT
ecj-11500	277	1	22	22	NUM
ecj-11500	277	2	.	.	PUNCT
ecj-11500	277	3	alvitigala	alvitigala	PROPN
ecj-11500	277	4	by	by	ADP
ecj-11500	277	5	,	,	PUNCT
ecj-11500	277	6	gooneratne	gooneratne	PROPN
ecj-11500	277	7	lv	lv	PROPN
ecj-11500	277	8	,	,	PUNCT
ecj-11500	277	9	dharmasena	dharmasena	PROPN
ecj-11500	277	10	i	i	PRON
ecj-11500	277	11	,	,	PUNCT
ecj-11500	277	12	et	et	PROPN
ecj-11500	277	13	al	al	PROPN
ecj-11500	277	14	.	.	PUNCT
ecj-11500	278	1	the	the	DET
ecj-11500	278	2	use	use	NOUN
ecj-11500	278	3	of	of	ADP
ecj-11500	278	4	rotational	rotational	ADJ
ecj-11500	278	5	thromboelastometry	thromboelastometry	NOUN
ecj-11500	278	6	parameters	parameter	NOUN
ecj-11500	278	7	in	in	ADP
ecj-11500	278	8	understanding	understand	VERB
ecj-11500	278	9	the	the	DET
ecj-11500	278	10	coagulopathy	coagulopathy	ADJ
ecj-11500	278	11	following	follow	VERB
ecj-11500	278	12	hump	hump	NOUN
ecj-11500	278	13	-	-	PUNCT
ecj-11500	278	14	nosed	nosed	NOUN
ecj-11500	278	15	viper	viper	NOUN
ecj-11500	278	16	(	(	PUNCT
ecj-11500	278	17	hypnale	hypnale	NOUN
ecj-11500	278	18	spp	spp	NOUN
ecj-11500	278	19	)	)	PUNCT
ecj-11500	278	20	bites	bite	NOUN
ecj-11500	278	21	:	:	PUNCT
ecj-11500	278	22	a	a	DET
ecj-11500	278	23	preliminary	preliminary	ADJ
ecj-11500	278	24	study	study	NOUN
ecj-11500	278	25	.	.	PUNCT
ecj-11500	279	1	trop	trop	X
ecj-11500	279	2	dis	dis	PROPN
ecj-11500	279	3	travel	travel	VERB
ecj-11500	279	4	med	med	ADJ
ecj-11500	279	5	vaccines	vaccine	NOUN
ecj-11500	279	6	2023;8:28	2023;8:28	ADJ
ecj-11500	279	7	.	.	PUNCT
ecj-11500	280	1	23	23	NUM
ecj-11500	280	2	.	.	PUNCT
ecj-11500	281	1	tinchon	tinchon	PROPN
ecj-11500	281	2	a	a	PRON
ecj-11500	281	3	,	,	PUNCT
ecj-11500	281	4	freydl	freydl	ADJ
ecj-11500	281	5	e	e	NOUN
ecj-11500	281	6	,	,	PUNCT
ecj-11500	281	7	fitzgerald	fitzgerald	PROPN
ecj-11500	281	8	rd	rd	PROPN
ecj-11500	281	9	,	,	PUNCT
ecj-11500	281	10	et	et	PROPN
ecj-11500	281	11	al	al	PROPN
ecj-11500	281	12	.	.	PUNCT
ecj-11500	282	1	real	real	ADJ
ecj-11500	282	2	-	-	PUNCT
ecj-11500	282	3	time	time	NOUN
ecj-11500	282	4	monitoring	monitoring	NOUN
ecj-11500	282	5	of	of	ADP
ecj-11500	282	6	intravenous	intravenous	ADJ
ecj-11500	282	7	thrombolysis	thrombolysis	NOUN
ecj-11500	282	8	in	in	ADP
ecj-11500	282	9	acute	acute	ADJ
ecj-11500	282	10	ischemic	ischemic	ADJ
ecj-11500	282	11	stroke	stroke	NOUN
ecj-11500	282	12	using	use	VERB
ecj-11500	282	13	rotational	rotational	ADJ
ecj-11500	282	14	thromboelastometry	thromboelastometry	NOUN
ecj-11500	282	15	:	:	PUNCT
ecj-11500	282	16	a	a	DET
ecj-11500	282	17	feasibility	feasibility	NOUN
ecj-11500	282	18	pilot	pilot	NOUN
ecj-11500	282	19	study	study	NOUN
ecj-11500	282	20	.	.	PUNCT
ecj-11500	283	1	j	j	PROPN
ecj-11500	283	2	neurol	neurol	PROPN
ecj-11500	283	3	2022;269:6129	2022;269:6129	PROPN
ecj-11500	283	4	-	-	SYM
ecj-11500	283	5	38	38	NUM
ecj-11500	283	6	.	.	PUNCT
ecj-11500	283	7	24	24	NUM
ecj-11500	283	8	.	.	PUNCT
ecj-11500	284	1	boss	boss	PROPN
ecj-11500	284	2	k	k	PROPN
ecj-11500	284	3	,	,	PUNCT
ecj-11500	284	4	kribben	kribben	PROPN
ecj-11500	284	5	a	a	PRON
ecj-11500	284	6	,	,	PUNCT
ecj-11500	284	7	tyczynski	tyczynski	ADJ
ecj-11500	284	8	b.	b.	PROPN
ecj-11500	284	9	pathological	pathological	ADJ
ecj-11500	284	10	findings	finding	NOUN
ecj-11500	284	11	in	in	ADP
ecj-11500	284	12	rotation	rotation	NOUN
ecj-11500	284	13	thromboelastometry	thromboelastometry	NOUN
ecj-11500	284	14	associated	associate	VERB
ecj-11500	284	15	with	with	ADP
ecj-11500	284	16	thromboembolic	thromboembolic	ADJ
ecj-11500	284	17	events	event	NOUN
ecj-11500	284	18	in	in	ADP
ecj-11500	284	19	covid-19	covid-19	PROPN
ecj-11500	284	20	patients	patient	NOUN
ecj-11500	284	21	.	.	PUNCT
ecj-11500	285	1	thromb	thromb	PROPN
ecj-11500	285	2	j	j	PROPN
ecj-11500	285	3	2021;19:10	2021;19:10	NUM
ecj-11500	285	4	.	.	PUNCT
ecj-11500	286	1	25	25	NUM
ecj-11500	286	2	.	.	PUNCT
ecj-11500	286	3	dennhardt	dennhardt	PROPN
ecj-11500	286	4	n	n	CCONJ
ecj-11500	286	5	,	,	PUNCT
ecj-11500	286	6	sümpelmann	sümpelmann	ADJ
ecj-11500	286	7	r	r	NOUN
ecj-11500	286	8	,	,	PUNCT
ecj-11500	286	9	horke	horke	NOUN
ecj-11500	286	10	a	a	NOUN
ecj-11500	286	11	,	,	PUNCT
ecj-11500	286	12	et	et	PROPN
ecj-11500	286	13	al	al	PROPN
ecj-11500	286	14	.	.	PROPN
ecj-11500	286	15	prevention	prevention	NOUN
ecj-11500	286	16	of	of	ADP
ecj-11500	286	17	postoperative	postoperative	ADJ
ecj-11500	286	18	bleeding	bleeding	NOUN
ecj-11500	286	19	after	after	ADP
ecj-11500	286	20	complex	complex	ADJ
ecj-11500	286	21	pediatric	pediatric	ADJ
ecj-11500	286	22	cardiac	cardiac	ADJ
ecj-11500	286	23	surgery	surgery	NOUN
ecj-11500	286	24	by	by	ADP
ecj-11500	286	25	early	early	ADJ
ecj-11500	286	26	administration	administration	NOUN
ecj-11500	286	27	of	of	ADP
ecj-11500	286	28	fibrinogen	fibrinogen	NOUN
ecj-11500	286	29	,	,	PUNCT
ecj-11500	286	30	prothrombin	prothrombin	NOUN
ecj-11500	286	31	complex	complex	NOUN
ecj-11500	286	32	and	and	CCONJ
ecj-11500	286	33	platelets	platelet	VERB
ecj-11500	286	34	:	:	PUNCT
ecj-11500	286	35	a	a	DET
ecj-11500	286	36	prospective	prospective	ADJ
ecj-11500	286	37	observational	observational	ADJ
ecj-11500	286	38	study	study	NOUN
ecj-11500	286	39	.	.	PUNCT
ecj-11500	287	1	bmc	bmc	ADJ
ecj-11500	287	2	anesthesiol	anesthesiol	NOUN
ecj-11500	287	3	2020;20:302	2020;20:302	NUM
ecj-11500	287	4	.	.	PUNCT
ecj-11500	288	1	26	26	NUM
ecj-11500	288	2	.	.	PUNCT
ecj-11500	289	1	kumar	kumar	PROPN
ecj-11500	289	2	m	m	PROPN
ecj-11500	289	3	,	,	PUNCT
ecj-11500	289	4	ahmad	ahmad	PROPN
ecj-11500	289	5	j	j	PROPN
ecj-11500	289	6	,	,	PUNCT
ecj-11500	289	7	maiwall	maiwall	PROPN
ecj-11500	289	8	r	r	NOUN
ecj-11500	289	9	,	,	PUNCT
ecj-11500	289	10	et	et	PROPN
ecj-11500	289	11	al	al	PROPN
ecj-11500	289	12	.	.	PUNCT
ecj-11500	290	1	thromboelastography	thromboelastography	NOUN
ecj-11500	290	2	-guided	-guided	ADJ
ecj-11500	290	3	blood	blood	NOUN
ecj-11500	290	4	component	component	NOUN
ecj-11500	290	5	use	use	NOUN
ecj-11500	290	6	in	in	ADP
ecj-11500	290	7	patients	patient	NOUN
ecj-11500	290	8	with	with	ADP
ecj-11500	290	9	cirrhosis	cirrhosis	NOUN
ecj-11500	290	10	with	with	ADP
ecj-11500	290	11	nonvariceal	nonvariceal	ADJ
ecj-11500	290	12	bleeding	bleeding	NOUN
ecj-11500	290	13	:	:	PUNCT
ecj-11500	290	14	a	a	DET
ecj-11500	290	15	randomized	randomized	ADJ
ecj-11500	290	16	controlled	control	VERB
ecj-11500	290	17	trial	trial	NOUN
ecj-11500	290	18	.	.	PUNCT
ecj-11500	291	1	hepatology	hepatology	NOUN
ecj-11500	291	2	2020;71:235	2020;71:235	PROPN
ecj-11500	291	3	-	-	SYM
ecj-11500	291	4	246	246	NUM
ecj-11500	291	5	.	.	PUNCT
ecj-11500	292	1	27	27	NUM
ecj-11500	292	2	.	.	PUNCT
ecj-11500	292	3	da	da	PROPN
ecj-11500	292	4	luz	luz	PROPN
ecj-11500	292	5	lt	lt	PROPN
ecj-11500	292	6	,	,	PUNCT
ecj-11500	292	7	nascimento	nascimento	PROPN
ecj-11500	292	8	b	b	PROPN
ecj-11500	292	9	,	,	PUNCT
ecj-11500	292	10	shankarakutty	shankarakutty	PROPN
ecj-11500	292	11	ak	ak	PROPN
ecj-11500	292	12	,	,	PUNCT
ecj-11500	292	13	et	et	PROPN
ecj-11500	292	14	al	al	PROPN
ecj-11500	292	15	.	.	PROPN
ecj-11500	292	16	effect	effect	NOUN
ecj-11500	292	17	of	of	ADP
ecj-11500	292	18	thromboelastography	thromboelastography	NOUN
ecj-11500	292	19	(	(	PUNCT
ecj-11500	292	20	teg	teg	PROPN
ecj-11500	292	21	®	®	PROPN
ecj-11500	292	22	)	)	PUNCT
ecj-11500	292	23	and	and	CCONJ
ecj-11500	292	24	rotational	rotational	ADJ
ecj-11500	292	25	thromboelastometry	thromboelastometry	NOUN
ecj-11500	292	26	(	(	PUNCT
ecj-11500	292	27	rotem	rotem	PROPN
ecj-11500	292	28	®	®	PROPN
ecj-11500	292	29	)	)	PUNCT
ecj-11500	292	30	on	on	ADP
ecj-11500	292	31	diagnosis	diagnosis	NOUN
ecj-11500	292	32	of	of	ADP
ecj-11500	292	33	coagulopathy	coagulopathy	ADJ
ecj-11500	292	34	,	,	PUNCT
ecj-11500	292	35	transfusion	transfusion	NOUN
ecj-11500	292	36	mini	mini	NOUN
ecj-11500	292	37	review	review	NOUN
ecj-11500	293	1	[	[	X
ecj-11500	293	2	page	page	NOUN
ecj-11500	293	3	11	11	NUM
ecj-11500	293	4	]	]	PUNCT
ecj-11500	294	1	[	[	X
ecj-11500	294	2	emergency	emergency	NOUN
ecj-11500	294	3	care	care	NOUN
ecj-11500	294	4	journal	journal	NOUN
ecj-11500	294	5	2023	2023	NUM
ecj-11500	294	6	;	;	PUNCT
ecj-11500	294	7	19:11500	19:11500	NUM
ecj-11500	294	8	]	]	X
ecj-11500	294	9	non	non	ADJ
ecj-11500	294	10	-co	-co	PROPN
ecj-11500	294	11	mmerc	mmerc	PROPN
ecj-11500	294	12	ial	ial	PROPN
ecj-11500	294	13	us	us	PROPN
ecj-11500	294	14	e	e	NOUN
ecj-11500	294	15	o	o	NOUN
ecj-11500	294	16	nly	nly	ADV
ecj-11500	294	17	guidance	guidance	NOUN
ecj-11500	294	18	and	and	CCONJ
ecj-11500	294	19	mortality	mortality	NOUN
ecj-11500	294	20	in	in	ADP
ecj-11500	294	21	trauma	trauma	NOUN
ecj-11500	294	22	:	:	PUNCT
ecj-11500	294	23	descriptive	descriptive	ADJ
ecj-11500	294	24	systematic	systematic	ADJ
ecj-11500	294	25	review	review	NOUN
ecj-11500	294	26	.	.	PUNCT
ecj-11500	295	1	crit	crit	PROPN
ecj-11500	295	2	care	care	PROPN
ecj-11500	295	3	2014;18:518	2014;18:518	PROPN
ecj-11500	295	4	.	.	PROPN
ecj-11500	295	5	28	28	NUM
ecj-11500	295	6	.	.	PUNCT
ecj-11500	296	1	david	david	PROPN
ecj-11500	296	2	j	j	PROPN
ecj-11500	296	3	-	-	PUNCT
ecj-11500	296	4	s	s	PROPN
ecj-11500	296	5	,	,	PUNCT
ecj-11500	296	6	james	james	PROPN
ecj-11500	296	7	a	a	PROPN
ecj-11500	296	8	,	,	PUNCT
ecj-11500	296	9	orion	orion	PROPN
ecj-11500	296	10	m	m	PROPN
ecj-11500	296	11	,	,	PUNCT
ecj-11500	296	12	et	et	PROPN
ecj-11500	296	13	al	al	PROPN
ecj-11500	296	14	.	.	PROPN
ecj-11500	296	15	thromboelastometry	thromboelastometry	NOUN
ecj-11500	296	16	-	-	PUNCT
ecj-11500	296	17	guided	guide	VERB
ecj-11500	296	18	haemostatic	haemostatic	ADJ
ecj-11500	296	19	resuscitation	resuscitation	NOUN
ecj-11500	296	20	in	in	ADP
ecj-11500	296	21	severely	severely	ADV
ecj-11500	296	22	injured	injure	VERB
ecj-11500	296	23	patients	patient	NOUN
ecj-11500	296	24	:	:	PUNCT
ecj-11500	296	25	a	a	DET
ecj-11500	296	26	propensity	propensity	NOUN
ecj-11500	296	27	score	score	NOUN
ecj-11500	296	28	-	-	PUNCT
ecj-11500	296	29	matched	match	VERB
ecj-11500	296	30	study	study	NOUN
ecj-11500	296	31	.	.	PUNCT
ecj-11500	297	1	crit	crit	PROPN
ecj-11500	297	2	care	care	NOUN
ecj-11500	297	3	.	.	PUNCT
ecj-11500	298	1	2023;27:141	2023;27:141	X
ecj-11500	298	2	.	.	NOUN
ecj-11500	298	3	29	29	NUM
ecj-11500	298	4	.	.	PUNCT
ecj-11500	299	1	baulig	baulig	PROPN
ecj-11500	299	2	w	w	PROPN
ecj-11500	299	3	,	,	PUNCT
ecj-11500	299	4	akbas	akbas	PROPN
ecj-11500	299	5	s	s	PROPN
ecj-11500	299	6	,	,	PUNCT
ecj-11500	299	7	schütt	schütt	PROPN
ecj-11500	299	8	pk	pk	PROPN
ecj-11500	299	9	,	,	PUNCT
ecj-11500	299	10	keul	keul	PROPN
ecj-11500	299	11	w	w	PROPN
ecj-11500	299	12	,	,	PUNCT
ecj-11500	299	13	jovic	jovic	PROPN
ecj-11500	299	14	m	m	PROPN
ecj-11500	299	15	,	,	PUNCT
ecj-11500	299	16	berdat	berdat	NOUN
ecj-11500	299	17	p	p	X
ecj-11500	299	18	,	,	PUNCT
ecj-11500	299	19	et	et	PROPN
ecj-11500	299	20	al	al	PROPN
ecj-11500	299	21	.	.	PROPN
ecj-11500	299	22	comparison	comparison	NOUN
ecj-11500	299	23	of	of	ADP
ecj-11500	299	24	the	the	DET
ecj-11500	299	25	resonance	resonance	NOUN
ecj-11500	299	26	sonorheometry	sonorheometry	NOUN
ecj-11500	299	27	based	base	VERB
ecj-11500	299	28	quantra	quantra	ADJ
ecj-11500	299	29	®	®	NOUN
ecj-11500	299	30	system	system	NOUN
ecj-11500	299	31	with	with	ADP
ecj-11500	299	32	rotational	rotational	ADJ
ecj-11500	299	33	thromboelastometry	thromboelastometry	PROPN
ecj-11500	299	34	rotem	rotem	PROPN
ecj-11500	299	35	®	®	PROPN
ecj-11500	299	36	sigma	sigma	PROPN
ecj-11500	299	37	in	in	ADP
ecj-11500	299	38	cardiac	cardiac	ADJ
ecj-11500	299	39	surgery	surgery	NOUN
ecj-11500	299	40	–	–	PUNCT
ecj-11500	299	41	a	a	DET
ecj-11500	299	42	prospective	prospective	ADJ
ecj-11500	299	43	observational	observational	ADJ
ecj-11500	299	44	study	study	NOUN
ecj-11500	299	45	.	.	PUNCT
ecj-11500	300	1	bmc	bmc	PROPN
ecj-11500	300	2	anesthesiol	anesthesiol	PROPN
ecj-11500	300	3	2021;21:260	2021;21:260	NUM
ecj-11500	300	4	.	.	NOUN
ecj-11500	300	5	30	30	NUM
ecj-11500	300	6	.	.	PUNCT
ecj-11500	301	1	hartmann	hartmann	PROPN
ecj-11500	301	2	j	j	PROPN
ecj-11500	301	3	,	,	PUNCT
ecj-11500	301	4	mason	mason	PROPN
ecj-11500	301	5	d	d	PROPN
ecj-11500	301	6	,	,	PUNCT
ecj-11500	301	7	achneck	achneck	PROPN
ecj-11500	301	8	h.	h.	PROPN
ecj-11500	301	9	thromboelastography	thromboelastography	PROPN
ecj-11500	301	10	(	(	PUNCT
ecj-11500	301	11	teg	teg	NOUN
ecj-11500	301	12	)	)	PUNCT
ecj-11500	301	13	point	point	NOUN
ecj-11500	301	14	-	-	PUNCT
ecj-11500	301	15	of	of	ADP
ecj-11500	301	16	-	-	PUNCT
ecj-11500	301	17	care	care	NOUN
ecj-11500	301	18	diagnostic	diagnostic	ADJ
ecj-11500	301	19	for	for	ADP
ecj-11500	301	20	hemostasis	hemostasis	NOUN
ecj-11500	301	21	management	management	NOUN
ecj-11500	301	22	.	.	PUNCT
ecj-11500	302	1	point	point	NOUN
ecj-11500	302	2	care	care	VERB
ecj-11500	302	3	2018;17:15	2018;17:15	NUM
ecj-11500	302	4	-	-	SYM
ecj-11500	302	5	22	22	NUM
ecj-11500	302	6	.	.	PUNCT
ecj-11500	303	1	31	31	NUM
ecj-11500	303	2	.	.	PUNCT
ecj-11500	303	3	henskens	henskens	PROPN
ecj-11500	303	4	ymc	ymc	PROPN
ecj-11500	303	5	,	,	PUNCT
ecj-11500	303	6	gulpen	gulpen	PROPN
ecj-11500	303	7	ajw	ajw	PROPN
ecj-11500	303	8	,	,	PUNCT
ecj-11500	303	9	van	van	PROPN
ecj-11500	303	10	oerle	oerle	NOUN
ecj-11500	303	11	r	r	NOUN
ecj-11500	303	12	,	,	PUNCT
ecj-11500	303	13	et	et	PROPN
ecj-11500	303	14	al	al	PROPN
ecj-11500	303	15	.	.	PUNCT
ecj-11500	304	1	detecting	detect	VERB
ecj-11500	304	2	clinically	clinically	ADV
ecj-11500	304	3	relevant	relevant	ADJ
ecj-11500	304	4	rivaroxaban	rivaroxaban	NOUN
ecj-11500	304	5	or	or	CCONJ
ecj-11500	304	6	dabigatran	dabigatran	NOUN
ecj-11500	304	7	levels	level	NOUN
ecj-11500	304	8	by	by	ADP
ecj-11500	304	9	routine	routine	ADJ
ecj-11500	304	10	coagulation	coagulation	NOUN
ecj-11500	304	11	tests	test	NOUN
ecj-11500	304	12	or	or	CCONJ
ecj-11500	304	13	thromboelastography	thromboelastography	VERB
ecj-11500	304	14	in	in	ADP
ecj-11500	304	15	a	a	DET
ecj-11500	304	16	cohort	cohort	NOUN
ecj-11500	304	17	of	of	ADP
ecj-11500	304	18	patients	patient	NOUN
ecj-11500	304	19	with	with	ADP
ecj-11500	304	20	atrial	atrial	ADJ
ecj-11500	304	21	fibrillation	fibrillation	NOUN
ecj-11500	304	22	.	.	PUNCT
ecj-11500	305	1	thromb	thromb	PROPN
ecj-11500	305	2	j	j	PROPN
ecj-11500	305	3	2018;16:3	2018;16:3	PROPN
ecj-11500	305	4	.	.	PUNCT
ecj-11500	306	1	32	32	NUM
ecj-11500	306	2	.	.	PUNCT
ecj-11500	307	1	hunt	hunt	NOUN
ecj-11500	307	2	h	h	NOUN
ecj-11500	307	3	,	,	PUNCT
ecj-11500	307	4	stanworth	stanworth	NOUN
ecj-11500	307	5	s	s	PROPN
ecj-11500	307	6	,	,	PUNCT
ecj-11500	307	7	curry	curry	NOUN
ecj-11500	307	8	n	n	CCONJ
ecj-11500	307	9	,	,	PUNCT
ecj-11500	307	10	et	et	PROPN
ecj-11500	307	11	al	al	PROPN
ecj-11500	307	12	.	.	PROPN
ecj-11500	308	1	thromboelastography	thromboelastography	PROPN
ecj-11500	308	2	(	(	PUNCT
ecj-11500	308	3	teg	teg	NOUN
ecj-11500	308	4	)	)	PUNCT
ecj-11500	308	5	and	and	CCONJ
ecj-11500	308	6	rotational	rotational	ADJ
ecj-11500	308	7	thromboelastometry	thromboelastometry	NOUN
ecj-11500	308	8	(	(	PUNCT
ecj-11500	308	9	rotem	rotem	PROPN
ecj-11500	308	10	)	)	PUNCT
ecj-11500	308	11	for	for	ADP
ecj-11500	308	12	trauma	trauma	NOUN
ecj-11500	308	13	-	-	PUNCT
ecj-11500	308	14	induced	induce	VERB
ecj-11500	308	15	coagulopathy	coagulopathy	ADJ
ecj-11500	308	16	in	in	ADP
ecj-11500	308	17	adult	adult	NOUN
ecj-11500	308	18	trauma	trauma	NOUN
ecj-11500	308	19	patients	patient	NOUN
ecj-11500	308	20	with	with	ADP
ecj-11500	308	21	bleeding	bleeding	NOUN
ecj-11500	308	22	.	.	PUNCT
ecj-11500	309	1	cochrane	cochrane	NOUN
ecj-11500	309	2	database	database	NOUN
ecj-11500	309	3	of	of	ADP
ecj-11500	309	4	systematic	systematic	ADJ
ecj-11500	309	5	reviews	review	NOUN
ecj-11500	309	6	.	.	PUNCT
ecj-11500	310	1	2015	2015	NUM
ecj-11500	310	2	.	.	PUNCT
ecj-11500	311	1	33	33	NUM
ecj-11500	311	2	.	.	PUNCT
ecj-11500	311	3	cannon	cannon	PROPN
ecj-11500	311	4	jw	jw	PROPN
ecj-11500	311	5	,	,	PUNCT
ecj-11500	311	6	dias	dias	PROPN
ecj-11500	311	7	jd	jd	PROPN
ecj-11500	311	8	,	,	PUNCT
ecj-11500	311	9	kumar	kumar	PROPN
ecj-11500	311	10	ma	ma	PROPN
ecj-11500	311	11	,	,	PUNCT
ecj-11500	311	12	et	et	PROPN
ecj-11500	311	13	al	al	PROPN
ecj-11500	311	14	.	.	PUNCT
ecj-11500	312	1	use	use	NOUN
ecj-11500	312	2	of	of	ADP
ecj-11500	312	3	thromboelastography	thromboelastography	NOUN
ecj-11500	312	4	in	in	ADP
ecj-11500	312	5	the	the	DET
ecj-11500	312	6	evaluation	evaluation	NOUN
ecj-11500	312	7	and	and	CCONJ
ecj-11500	312	8	management	management	NOUN
ecj-11500	312	9	of	of	ADP
ecj-11500	312	10	patients	patient	NOUN
ecj-11500	312	11	with	with	ADP
ecj-11500	312	12	traumatic	traumatic	ADJ
ecj-11500	312	13	brain	brain	NOUN
ecj-11500	312	14	injury	injury	NOUN
ecj-11500	312	15	:	:	PUNCT
ecj-11500	312	16	a	a	DET
ecj-11500	312	17	systematic	systematic	ADJ
ecj-11500	312	18	review	review	NOUN
ecj-11500	312	19	and	and	CCONJ
ecj-11500	312	20	meta	meta	ADJ
ecj-11500	312	21	-	-	PUNCT
ecj-11500	312	22	analysis	analysis	NOUN
ecj-11500	312	23	.	.	PUNCT
ecj-11500	313	1	crit	crit	PROPN
ecj-11500	313	2	care	care	PROPN
ecj-11500	313	3	explor	explor	PROPN
ecj-11500	313	4	2021;3	2021;3	NOUN
ecj-11500	313	5	:	:	PUNCT
ecj-11500	313	6	e0526	e0526	NOUN
ecj-11500	313	7	.	.	PUNCT
ecj-11500	314	1	34	34	NUM
ecj-11500	314	2	.	.	PUNCT
ecj-11500	314	3	bugaev	bugaev	PROPN
ecj-11500	314	4	n	n	CCONJ
ecj-11500	314	5	,	,	PUNCT
ecj-11500	314	6	como	como	PROPN
ecj-11500	314	7	jj	jj	PROPN
ecj-11500	314	8	,	,	PUNCT
ecj-11500	314	9	golani	golani	PROPN
ecj-11500	314	10	g	g	PROPN
ecj-11500	314	11	,	,	PUNCT
ecj-11500	314	12	et	et	PROPN
ecj-11500	314	13	al	al	PROPN
ecj-11500	314	14	.	.	PROPN
ecj-11500	314	15	thromboelastography	thromboelastography	NOUN
ecj-11500	314	16	and	and	CCONJ
ecj-11500	314	17	rotational	rotational	ADJ
ecj-11500	314	18	thromboelastometry	thromboelastometry	NOUN
ecj-11500	314	19	in	in	ADP
ecj-11500	314	20	bleeding	bleed	VERB
ecj-11500	314	21	patients	patient	NOUN
ecj-11500	314	22	with	with	ADP
ecj-11500	314	23	coagulopathy	coagulopathy	ADJ
ecj-11500	314	24	:	:	PUNCT
ecj-11500	314	25	practice	practice	NOUN
ecj-11500	314	26	management	management	NOUN
ecj-11500	314	27	guideline	guideline	NOUN
ecj-11500	314	28	from	from	ADP
ecj-11500	314	29	the	the	DET
ecj-11500	314	30	eastern	eastern	ADJ
ecj-11500	314	31	association	association	NOUN
ecj-11500	314	32	for	for	ADP
ecj-11500	314	33	the	the	DET
ecj-11500	314	34	surgery	surgery	NOUN
ecj-11500	314	35	of	of	ADP
ecj-11500	314	36	trauma	trauma	NOUN
ecj-11500	314	37	.	.	PUNCT
ecj-11500	315	1	j	j	PROPN
ecj-11500	315	2	trauma	trauma	PROPN
ecj-11500	315	3	acute	acute	PROPN
ecj-11500	315	4	care	care	PROPN
ecj-11500	315	5	surg	surg	PROPN
ecj-11500	315	6	2020;89:999	2020;89:999	NOUN
ecj-11500	315	7	-	-	PUNCT
ecj-11500	315	8	1017	1017	NUM
ecj-11500	315	9	.	.	PUNCT
ecj-11500	316	1	35	35	NUM
ecj-11500	316	2	.	.	PUNCT
ecj-11500	317	1	artang	artang	PROPN
ecj-11500	317	2	r	r	PROPN
ecj-11500	317	3	,	,	PUNCT
ecj-11500	317	4	anderson	anderson	PROPN
ecj-11500	317	5	m	m	PROPN
ecj-11500	317	6	,	,	PUNCT
ecj-11500	317	7	nielsen	nielsen	PROPN
ecj-11500	317	8	jd	jd	PROPN
ecj-11500	317	9	.	.	PUNCT
ecj-11500	317	10	fully	fully	ADV
ecj-11500	317	11	automated	automate	VERB
ecj-11500	317	12	thromboelastograph	thromboelastograph	PROPN
ecj-11500	317	13	teg	teg	PROPN
ecj-11500	317	14	6s	6s	PROPN
ecj-11500	317	15	to	to	PART
ecj-11500	317	16	measure	measure	VERB
ecj-11500	317	17	anticoagulant	anticoagulant	ADJ
ecj-11500	317	18	effects	effect	NOUN
ecj-11500	317	19	of	of	ADP
ecj-11500	317	20	direct	direct	ADJ
ecj-11500	317	21	oral	oral	ADJ
ecj-11500	317	22	anticoagulants	anticoagulant	NOUN
ecj-11500	317	23	in	in	ADP
ecj-11500	317	24	healthy	healthy	ADJ
ecj-11500	317	25	male	male	NOUN
ecj-11500	317	26	volunteers	volunteer	NOUN
ecj-11500	317	27	.	.	PUNCT
ecj-11500	318	1	res	re	NOUN
ecj-11500	318	2	practice	practice	NOUN
ecj-11500	318	3	thromb	thromb	NOUN
ecj-11500	318	4	haemost	haemost	VERB
ecj-11500	318	5	2019;3:391	2019;3:391	NOUN
ecj-11500	318	6	-	-	SYM
ecj-11500	318	7	6	6	NUM
ecj-11500	318	8	.	.	NUM
ecj-11500	318	9	36	36	NUM
ecj-11500	318	10	.	.	PUNCT
ecj-11500	319	1	el	el	PROPN
ecj-11500	319	2	-	-	PROPN
ecj-11500	319	3	menyar	menyar	PROPN
ecj-11500	319	4	a	a	PROPN
ecj-11500	319	5	,	,	PUNCT
ecj-11500	319	6	ahmed	ahmed	PROPN
ecj-11500	319	7	k	k	PROPN
ecj-11500	319	8	,	,	PUNCT
ecj-11500	319	9	hakim	hakim	PROPN
ecj-11500	319	10	s	s	PART
ecj-11500	319	11	,	,	PUNCT
ecj-11500	319	12	et	et	PROPN
ecj-11500	319	13	al	al	PROPN
ecj-11500	319	14	.	.	PROPN
ecj-11500	319	15	efficacy	efficacy	NOUN
ecj-11500	319	16	and	and	CCONJ
ecj-11500	319	17	safety	safety	NOUN
ecj-11500	319	18	of	of	ADP
ecj-11500	319	19	the	the	DET
ecj-11500	319	20	second	second	ADJ
ecj-11500	319	21	in	in	ADP
ecj-11500	319	22	-	-	PUNCT
ecj-11500	319	23	hospital	hospital	NOUN
ecj-11500	319	24	dose	dose	NOUN
ecj-11500	319	25	of	of	ADP
ecj-11500	319	26	tranexamic	tranexamic	ADJ
ecj-11500	319	27	acid	acid	NOUN
ecj-11500	319	28	after	after	ADP
ecj-11500	319	29	receiving	receive	VERB
ecj-11500	319	30	the	the	DET
ecj-11500	319	31	prehospital	prehospital	NOUN
ecj-11500	319	32	dose	dose	PROPN
ecj-11500	319	33	:	:	PUNCT
ecj-11500	319	34	double	double	ADJ
ecj-11500	319	35	-	-	PUNCT
ecj-11500	319	36	blind	blind	ADJ
ecj-11500	319	37	randomized	randomize	VERB
ecj-11500	319	38	controlled	control	VERB
ecj-11500	319	39	clinical	clinical	ADJ
ecj-11500	319	40	trial	trial	NOUN
ecj-11500	319	41	in	in	ADP
ecj-11500	319	42	a	a	DET
ecj-11500	319	43	level	level	NOUN
ecj-11500	319	44	1	1	NUM
ecj-11500	319	45	trauma	trauma	NOUN
ecj-11500	319	46	center	center	NOUN
ecj-11500	319	47	.	.	PUNCT
ecj-11500	320	1	eur	eur	PROPN
ecj-11500	320	2	j	j	PROPN
ecj-11500	320	3	trauma	trauma	PROPN
ecj-11500	320	4	emerg	emerg	PROPN
ecj-11500	320	5	surg	surg	NOUN
ecj-11500	320	6	2022;48:3089	2022;48:3089	NUM
ecj-11500	320	7	-	-	SYM
ecj-11500	320	8	99	99	NUM
ecj-11500	320	9	.	.	PUNCT
ecj-11500	320	10	37	37	NUM
ecj-11500	320	11	.	.	PUNCT
ecj-11500	320	12	stabler	stable	ADJ
ecj-11500	320	13	sn	sn	PROPN
ecj-11500	320	14	,	,	PUNCT
ecj-11500	320	15	li	li	PROPN
ecj-11500	320	16	ss	ss	PROPN
ecj-11500	320	17	,	,	PUNCT
ecj-11500	320	18	karpov	karpov	PROPN
ecj-11500	320	19	a	a	X
ecj-11500	320	20	,	,	PUNCT
ecj-11500	320	21	vu	vu	X
ecj-11500	320	22	en	en	X
ecj-11500	320	23	.	.	PUNCT
ecj-11500	321	1	use	use	NOUN
ecj-11500	321	2	of	of	ADP
ecj-11500	321	3	fibrinogen	fibrinogen	NOUN
ecj-11500	321	4	concentrate	concentrate	NOUN
ecj-11500	321	5	for	for	ADP
ecj-11500	321	6	trauma	trauma	NOUN
ecj-11500	321	7	-	-	PUNCT
ecj-11500	321	8	related	relate	VERB
ecj-11500	321	9	bleeding	bleeding	NOUN
ecj-11500	321	10	:	:	PUNCT
ecj-11500	321	11	a	a	DET
ecj-11500	321	12	systematic	systematic	ADJ
ecj-11500	321	13	-	-	PUNCT
ecj-11500	321	14	review	review	NOUN
ecj-11500	321	15	and	and	CCONJ
ecj-11500	321	16	meta	meta	ADJ
ecj-11500	321	17	-	-	PUNCT
ecj-11500	321	18	analysis	analysis	NOUN
ecj-11500	321	19	.	.	PUNCT
ecj-11500	322	1	j	j	PROPN
ecj-11500	322	2	trauma	trauma	PROPN
ecj-11500	322	3	acute	acute	PROPN
ecj-11500	322	4	care	care	NOUN
ecj-11500	322	5	surg	surg	NOUN
ecj-11500	322	6	2020;89:1212	2020;89:1212	NUM
ecj-11500	322	7	-	-	SYM
ecj-11500	322	8	24	24	NUM
ecj-11500	322	9	.	.	PUNCT
ecj-11500	323	1	mini	mini	ADJ
ecj-11500	323	2	review	review	NOUN
ecj-11500	323	3	[	[	X
ecj-11500	323	4	emergency	emergency	NOUN
ecj-11500	323	5	care	care	NOUN
ecj-11500	323	6	journal	journal	NOUN
ecj-11500	323	7	2023	2023	NUM
ecj-11500	323	8	;	;	PUNCT
ecj-11500	323	9	19:11500	19:11500	NUM
ecj-11500	323	10	]	]	X
ecj-11500	324	1	[	[	X
ecj-11500	324	2	page	page	NOUN
ecj-11500	324	3	12	12	NUM
ecj-11500	324	4	]	]	PUNCT
ecj-11500	324	5	non	non	ADJ
ecj-11500	324	6	-co	-co	PROPN
ecj-11500	324	7	mmerc	mmerc	PROPN
ecj-11500	324	8	ial	ial	PROPN
ecj-11500	324	9	us	us	PROPN
ecj-11500	324	10	e	e	NOUN
ecj-11500	324	11	o	o	NOUN
ecj-11500	324	12	nly	nly	ADV