# bib

id: cord-268750-kox3uah2
author: Wong, S. F.
date: 2004-01-08
extension: .txt
mime: text/plain
words: 1585
sentence: 77
flesch: 52
cache: cache/cord-268750-kox3uah2.txt
txt: txt/cord-268750-kox3uah2.txt
title:
  Measures to Prevent Healtcare Workers from Contracting Severe Acute Respiratory Syndrome During High-Risk Surgical Procedures

summary:
  Although the CDC provided guidelines for the prevention and control of SARS infection on 6 May 2003 [4] , those guidelines have, to the best of our knowledge, never been tested for the procedure described here. Maternal SARS infection was clearly labeled on the laboratory forms.


id: cord-335671-j3wrtsxj
author: Wagenvoort, J. H. T.
date: 2004-12-14
extension: .txt
mime: text/plain
words: 988
sentence: 38
flesch: 47
cache: cache/cord-335671-j3wrtsxj.txt
txt: txt/cord-335671-j3wrtsxj.txt
title:
  Similar environmental survival patterns of Streptococcus pyogenes strains of different epidemiologic backgrounds and clinical severity

summary:
  Our finding that S. pyogenes strains survive in the inanimate environment for up to 1 month shows that contact transmission is facilitated in the short-term phase of an outbreak; however, long-term environmental survival cannot be considered an important factor in the dynamics of S. pyogenes transmission. The survival rates of the different groups of S. pyogenes strains are shown in Table 1 .


id: cord-311207-qkkn0297
author: Pegoraro, Manuela
date: 2020-10-20
extension: .txt
mime: text/plain
words: 1667
sentence: 66
flesch: 39
cache: cache/cord-311207-qkkn0297.txt
txt: txt/cord-311207-qkkn0297.txt
title:
  Evaluation of three immunochromatographic tests in COVID-19 serologic diagnosis and their clinical usefulness

summary:
  Sensitivities were assessed on confirmed COVID-19 cases, combining IgG and IgM/IgA positive results, while specificities were estimated on the group of healthy volunteer's. Then, about half of blood samples from COVID-19 confirmed cases had been collected in the early stage, when antibodies are usually absent, thus partially impacting the diagnostic sensitivity.


id: cord-293710-f1tzt6jb
author: Karolyi, M.
title: Late onset pulmonary embolism in young male otherwise healthy COVID-19 patients
date: 2020-09-23
extension: .txt
mime: text/plain
words: 1428
sentence: 70
flesch: 46
cache: cache/cord-293710-f1tzt6jb.txt
txt: txt/cord-293710-f1tzt6jb.txt
summary:
  This should raise suspicion of PE even in patients who received prophylactic anticoagulation as shown by patient 3. After initial resolution of symptoms patients had to be admitted to the Kaiser-Franz-Josef Hospital because of new onset of symptoms.


id: cord-006478-qkw1ik4e
author: Blahová, J.
date: 1999
extension: .txt
mime: text/plain
words: 1314
sentence: 38
flesch: 28
cache: cache/cord-006478-qkw1ik4e.txt
txt: txt/cord-006478-qkw1ik4e.txt
title:
  High-Frequency Transduction of Antibiotic Resistance in Pseudomonas aeruginosa by a Wild-Type Bacteriophage with Restricted Specificity for Recipient Strains

summary:
  In contrast to other wild-type phages isolated from multiple-drug-resistant nosocomial strains of Pseudomonas aeruginosa [3, 5, 9] , the phage lysate of Pseudomonas aeruginosa 103 showed a lytic reaction when added, in dilution of up to 10 -12 , to the recipient strain Pseudomonas aeruginosa PAO 1670 (Figure 1 ) but not to the other strains. Transferable resistance to specific antibiotics in nosocomial strains of Pseudomonas aeruginosa from two teaching hospitals Cross-resistance to meropenem, cephems and quinolones in Pseudomonas aeruginosa Ceftazidime resistance in Pseudomonas aeruginosa: transduction by a wild-type phage Transduction of imipenem resistance by the phage F-116 from a nosocomial strain of Pseudomonas aeruginosa in Slovakia Transduction of antibiotic resistance including imipenem resistance in nosocomial Pseudomonas aeruginosa strains by wild-type phages Insertion of a carbapenemase gene casette into an integron of a Pseudomonas aeruginosa plasmid The genetic organisation of arginine biosynthesis in Pseudomonas aeruginosa Resistance of Pseudomonas aeruginosa PAO to nalidixic acid and low-levels of beta-lactams: mapping of chromosomal genes Transduction of imipenem resistance by wild-type bacteriophages from three Pseudomonas aeruginosa strains from a single clinical source Plasmid-mediated dissemination of the metallo-blactamase gene bla IMP among clinically isolated strains of Serratia marcescens Molecular characterization of an enterobacterial metallo-b-lactamase found in a clinical isolate of Serratia marcescens that shows imipenem resistance Akan Department of Microbiology, Faculty of Medicine 5-20% of acute and chronic hepatitis cases are of unknown etiology.


id: cord-291052-nstfe15a
author: Cag, Yasemin
title: A novel approach to managing COVID-19 patients; results of lopinavir plus doxycycline cohort
date: 2020-08-27
extension: .txt
mime: text/plain
words: 1937
sentence: 98
flesch: 50
cache: cache/cord-291052-nstfe15a.txt
txt: txt/cord-291052-nstfe15a.txt
summary:
  In other words, if not correctly managed, this panic had the potential to consume hospital resources reserved for severe patients. key: cord-291052-nstfe15a authors: Cag, Yasemin; Icten, Sacit; Isik-Goren, Burcu; Baysal, Naciye Betul; Bektas, Begum; Selvi, Ece; Ergen, Pinar; Aydin, Ozlem; Ucisik, Ayse Canan; Yilmaz-Karadag, Fatma; Caskurlu, Hulya; Akarsu-Ayazoglu, Tulin; Kocoglu, Hasan; Uzman, Sinan; Nural-Pamukcu, Muge; Arslan, Ferhat; Bas, Gurhan; Kalcioglu, Mahmut Tayyar; Vahaboglu, Haluk title: A novel approach to managing COVID-19 patients; results of lopinavir plus doxycycline cohort date: 2020-08-27 journal:


id: cord-006325-3no74e74
author: Jeannoël, M.
title: Microorganisms associated with respiratory syncytial virus pneumonia in the adult population
date: 2018-10-23
extension: .txt
mime: text/plain
words: 1956
sentence: 89
flesch: 35
cache: cache/cord-006325-3no74e74.txt
txt: txt/cord-006325-3no74e74.txt
summary:
  A more severe outcome was observed for RSV-bacteria-associated pneumonia compared with RSV pneumonia: length of stay was significantly longer (16 days vs 10 days) and ICU hospitalization more frequent (66.7% vs 21.0%) The aim of our study was to gain insights in the epidemiology of bacterial superinfections associated with RSV pneumonia in adults.


id: cord-006448-elfroq6f
author: Hakim, F. A.
title: Severe adenovirus pneumonia in immunocompetent adults: a case report and review of the literature
date: 2007-11-21
extension: .txt
mime: text/plain
words: 2167
sentence: 125
flesch: 34
cache: cache/cord-006448-elfroq6f.txt
txt: txt/cord-006448-elfroq6f.txt
summary:
  Severe adenovirus infections causing significant morbidity and mortality are well described in immunocompromised patients but are extremely rare in healthy immunocompetent adults [1] . However, severe adenovirus infections among immunocompetent adults raised concern when Ryan et al. reported related deaths in two military recruits in 2001


id: cord-321455-ooouqna7
author: Li, Tao
date: 2020-07-01
extension: .txt
mime: text/plain
words: 2118
sentence: 82
flesch: 44
cache: cache/cord-321455-ooouqna7.txt
txt: txt/cord-321455-ooouqna7.txt
title:
  Characteristics of laboratory indexes in COVID-19 patients with non-severe symptoms in Hefei City, China: diagnostic value in organ injuries

summary:
  Statistical charts were drawn using GraphPad Prism 8. The LYMPH, EO, and BSO counts in patients with COVID-19 were significantly lower, compared with the controls on the 1st, 4th, 7th, and 10th days of admission, while the MONO counts were significantly higher in COVID-19 patients ( Fig. 1a-d) . *Because the concentrations of IL-1β in patients and IL-10 in controls are below the lower limit of the measurement range, we use the lower limit value of the measurement range as statistical data Analyses of hemostasis, coagulation, and fibrinolysisrelated systems APTT and PT for COVID-19 patients were significantly longer than those in controls, and FDP, D-D, FIB, and PT-INR were higher compared with those in the controls (Table 2 and Fig. 4a f).


id: cord-006490-jo8dhtb0
author: Maillet, M.
date: 2013-08-30
extension: .txt
mime: text/plain
words: 2533
sentence: 96
flesch: 35
cache: cache/cord-006490-jo8dhtb0.txt
txt: txt/cord-006490-jo8dhtb0.txt
title:
  Pneumocystis jirovecii (Pj) quantitative PCR to differentiate Pj pneumonia from Pj colonization in immunocompromised patients

summary:
  Trends in hospitalizations for AIDS-associated Pneumocystis jirovecii pneumonia in the United States Management and outcome patterns for adult Pneumocystis carinii pneumonia, 1985 to 1995: comparison of HIV-associated cases to other immunocompromised states Pneumocystis pneumonia Comparison between realtime PCR, conventional PCR and different staining techniques for diagnosing Pneumocystis jiroveci pneumonia from bronchoalveolar lavage specimens Clinical significance of quantifying Pneumocystis jirovecii DNA by using real-time PCR in bronchoalveolar lavage fluid from immunocompromised patients Molecular diagnosis of Pneumocystis pneumonia Colonization by Pneumocystis jirovecii and its role in disease Characteristics and clinical relevance of the quantitative touch-down major surface glycoprotein polymerase chain reaction in the diagnosis of Pneumocystis pneumonia Update on the diagnosis and treatment of Pneumocystis pneumonia Epidemiology and clinical significance of Pneumocystis colonization Pneumocystis colonization is highly prevalent in the autopsied lungs of the general population Epidemiology of Pneumocystis colonization in families Pneumocystis infections: the iceberg? Pneumocystis infection: unraveling the colonization-to-disease shift Pneumocystis jirovecii colonization in patients with systemic autoimmune diseases: prevalence, risk factors of colonization and outcome Pneumocystis jirovecii in general population Asymptomatic carriage of Pneumocystis jiroveci in subjects undergoing bronchoscopy: a prospective study Development and evaluation of a quantitative, touch-down, real-time PCR assay for diagnosing Pneumocystis carinii pneumonia Early diagnosis and treatment are crucial for the survival of Pneumocystis pneumonia patients without human immunodeficiency virus infection Current insights into the biology and pathogenesis of Pneumocystis pneumonia Use of real-time polymerase chain reaction for the diagnosis of Pneumocystis pneumonia in immunocompromised patients: a metaanalysis Real-time PCR assay-based strategy for differentiation between active Pneumocystis jirovecii pneumonia and colonization in immunocompromised patients Quantitative real-time PCR and the (1→3)-β-D-glucan assay for differentiation between Pneumocystis jirovecii pneumonia and colonization PCR diagnosis of Pneumocystis pneumonia: a bivariate meta-analysis Contribution of the (1→3)-β-D-glucan assay for diagnosis of invasive fungal infections Diagnostic accuracy of serum 1,3-β-D-glucan for Pneumocystis jiroveci pneumonia, invasive candidiasis, and invasive aspergillosis: systematic review and meta-analysis A recent study concluded that early diagnosis and treatment are crucial for the survival of PCP patients without HIV infection


id: cord-006581-f957o5z3
author: Gizzi, M.
date: 2013-05-14
extension: .txt
mime: text/plain
words: 2427
sentence: 100
flesch: 42
cache: cache/cord-006581-f957o5z3.txt
txt: txt/cord-006581-f957o5z3.txt
title:
  Another case of “European hantavirus pulmonary syndrome” with severe lung, prior to kidney, involvement, and diagnosed by viral inclusions in lung macrophages

summary:
  Hantavirus pulmonary syndrome caused by European hantavirus Plasma exchange-associated immunoglobulin M-negative hantavirus disease after a camping holiday in southern France Pulmonary-renal syndrome due to hemorrhagic fever with renal syndrome: an unusual manifestation of Puumala virus infection in France Hantavirus nephropathy in Belgium: description of 2 new cases originating in southern provinces Epidemic of hantavirus disease in Entre-Sambre-et-Meuse: year 1992-1993. Finally, initial blurred vision due to transient shallowing of the anterior eye chamber is an often overlooked but very specific clinical sign in NE and, to a lesser degree, HFRS cases [1, 10, 15] , but have not been reported so far in HPS cases from the Americas.


id: cord-006344-de4dhv4b
author: Seitsonen, E.
date: 2006-03-21
extension: .txt
mime: text/plain
words: 2776
sentence: 151
flesch: 45
cache: cache/cord-006344-de4dhv4b.txt
txt: txt/cord-006344-de4dhv4b.txt
title:
  Corticosteroids combined with continuous veno-venous hemodiafiltration for treatment of hantavirus pulmonary syndrome caused by Puumala virus infection

summary:
  The two Table 2 Platelet counts (PC, ×10 9 /l) and C-reactive protein values (CRP, mg/l) in cases 1 and 2 on consecutive days POS during the period of ICU treatment (days 7-21 POS and 5-15 POS for cases 1 and 2, respectively) survivors who required mechanical ventilation were extubated after 5 days and made a full recovery. [18] demon-strated that at the onset of pulmonary edema, HPS patients have abundant viremia which clears rapidly after the resolution of fever, while respiratory distress may persist.


id: cord-006174-xrhqisii
author: López-Rodríguez, M.
title: IFITM3 and severe influenza virus infection. No evidence of genetic association
date: 2016-08-04
extension: .txt
mime: text/plain
words: 2821
sentence: 131
flesch: 49
cache: cache/cord-006174-xrhqisii.txt
txt: txt/cord-006174-xrhqisii.txt
summary:
  These data may be relevant to recognize whether patients homozygous for rs12252-C are at risk of severe influenza, and hence require individualized measures in the case of IVI. It has been proposed that homozygosity for the rs12252-C allele is associated with development of severe influenza in Northern Europeans and severe IAV infection in Asians [9, 12, 13] .


id: cord-006302-pnnkfid0
author: Ioakeimidou, A.
date: 2017-04-28
extension: .txt
mime: text/plain
words: 2947
sentence: 138
flesch: 48
cache: cache/cord-006302-pnnkfid0.txt
txt: txt/cord-006302-pnnkfid0.txt
title:
  Increase of circulating endocan over sepsis follow-up is associated with progression into organ dysfunction

summary:
  Community-and healthcareassociated infections in critically ill patients: a multicenter cohort study The third international consensus definitions for sepsis and septic shock (sepsis-3) Sepsis-induced immunosuppression: from cellular dysfunctions to immunotherapy Angiopoietins in angiogenesis and beyond Endocan is a novel chondroitin sulfate/dermatan sulfate proteoglycan that promotes hepatocyte growth factor/scatter factor mitogenic activity SIS international sepsis definitions conference The international sepsis forum consensus definitions of infections in the intensive care unit Diagnosis and treatment of disseminated intravascular coagulation (DIC) according to four DIC guidelines Endothelial cell-specific molecule-1/endocan: diagnostic and prognostic value in patients suffering from severe sepsis and septic shock Identification of a 14kDa fragment generated by cathepsin G, a novel circulating biomarker in sepsis Endocan, a new endothelial marker in human sepsis Characteristics of serum endocan levels in infection Lower serum endocan levels are associated with the development of acute lung injury after major trauma Evaluation of endothelial biomarkers as predictors of organ failures in septic shock patients Endocan is a useful biomarker of survival and severity in sepsis Endocan levels in peripheral blood predict outcomes of acute respiratory distress syndrome Inhibition of caspase-1 activation in gram-negative sepsis and experimental endotoxemia Reversal of immunoparalysis in humans in vivo: a double-blind, placebo-controlled, randomized pilot study Endocan and Ang-2 were the only parameters that were significantly increased among patients who worsened.


id: cord-006714-q7wy76e2
author: Delannoy, P.-Y.
title: Impact of combination therapy with aminoglycosides on the outcome of ICU-acquired bacteraemias
date: 2012-02-15
extension: .txt
mime: text/plain
words: 2881
sentence: 154
flesch: 41
cache: cache/cord-006714-q7wy76e2.txt
txt: txt/cord-006714-q7wy76e2.txt
summary:
  ICU patients with or without bacteraemia have an increased volume of distribution. Effect of aminoglycoside and beta-lactam combination therapy versus beta-lactam monotherapy on the emergence of antimicrobial resistance: a meta-analysis of randomized, controlled trials Does combination antimicrobial therapy reduce mortality in Gram-negative bacteraemia?


id: cord-000364-ikq38rm1
author: Rasmuson, J.
date: 2011-01-15
extension: .txt
mime: text/plain
words: 2843
sentence: 143
flesch: 39
cache: cache/cord-000364-ikq38rm1.txt
txt: txt/cord-000364-ikq38rm1.txt
title:
  Time to revise the paradigm of hantavirus syndromes? Hantavirus pulmonary syndrome caused by European hantavirus

summary:
  Hantavirus pulmonary syndrome caused by European hantavirus date: 2011-01-15 journal: Eur J Clin Microbiol Infect Dis DOI: 10.1007/s10096-010-1141-6 sha: doc_id: 364 cord_uid: ikq38rm1 Hantaviruses have previously been recognised to cause two separate syndromes: hemorrhagic fever with renal syndrome in Eurasia, and hantavirus pulmonary syndrome (HPS) in the Americas. Pathogenesis of an emerging infectious disease Hantavirus regulation of endothelial cell functions Hantavirus infection induces a typical myocarditis that may be responsible for myocardial depression and shock in hantavirus pulmonary syndrome Pulmonary involvement in nephropathia epidemica as demonstrated by computed tomography Impaired pulmonary function in patients with hemorrhagic fever with renal syndrome Pulmonary involvement in nephropathia epidemica: radiological findings and their clinical correlations Hantavirus pulmonary syndrome in New England and Europe Puumala virus pulmonary syndrome in a Romanian immigrant Puumala virus RNA in patient with multiorgan failure Corticosteroids combined with continuous veno-venous hemodiafiltration for treatment of hantavirus pulmonary syndrome caused by Puumala virus infection Outbreak of Puumala virus infection Puumala hantavirus viremia diagnosed by real-time reverse transcriptase PCR using samples from patients with hemorrhagic fever and renal syndrome Hantavirus pulmonary syndrome, 2010 case definition Hantavirus pulmonary syndrome: the new American hemorrhagic fever Outbreak of hantavirus pulmonary syndrome Electrocardiographic changes in patients with haemorrhagic fever with renal syndrome More than half of the patients with acute Puumala hantavirus infection have abnormal cardiac findings Prospective evaluation of household contacts of persons with hantavirus cardiopulmonary syndrome in Chile Acknowledgements Irene Eriksson and Ingrid Gustafsson are greatly acknowledged for their skilled technical assistance.


id: cord-006335-j74hnoag
author: Clement, J.
date: 2011-11-09
extension: .txt
mime: text/plain
words: 2850
sentence: 91
flesch: 39
cache: cache/cord-006335-j74hnoag.txt
txt: txt/cord-006335-j74hnoag.txt
title:
  A unifying hypothesis and a single name for a complex globally emerging infection: hantavirus disease

summary:
  In: Casalegno S (ed) Global warming impacts-case studies on the economy, human health, and on urban and natural environments Hantavirus pulmonary syndrome (hantavirus disease) (HPS), 2010 case definition Hantavirus pulmonary syndrome in New England and Europe, author reply Hantavirus pulmonary syndrome in New England and Europe Puumala virus infection without signs of renal involvement Hantavirus pulmonary syndrome: the new American hemorrhagic fever Increased permeability of human endothelial cell line EA.hy926 induced by hantavirus-specific cytotoxic T lymphocytes T cells and pathogenesis of hantavirus cardiopulmonary syndrome and hemorrhagic fever with renal syndrome Hantavirus nephropathy in Belgium: description of 2 new cases originating in southern provinces Isolation of a hantavirus from a severely ill patient with hemorrhagic fever with renal syndrome in Greece A soldier in respiratory distress Life-threatening Dobrava hantavirus infection with unusually extended pulmonary involvement Occurrence of renal and pulmonary syndrome in a region of northeast Germany where Tula hantavirus circulates The hantaviruses of Europe: from the bedside to the bench Incidence rate for hantavirus infections without pulmonary syndrome Acute Sin Nombre hantavirus infection without pulmonary syndrome, United States First evidence of fatal hantavirus nephropathy in India, mimicking leptospirosis Acute kidney injury in emerging, non-tropical infections Acute renal failure definitions and classification: time for change? Developing a consensus classification system for acute renal failure Acute renal failuredefinition, outcome measures, animal models, fluid therapy and information technology needs Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury When to start dialysis in patients with acute kidney injury? Hantavirus pulmonary syndrome caused by European hantavirus World Health Organization (WHO) (1983) Haemorrhagic fever with renal syndrome: memorandum from a WHO meeting Hantavirus pulmonary syndrome: a clinical description of 17 patients with a newly recognized disease Aetiological relation between Korean haemorrhagic fever and nephropathia epidemica Hantaviruses: immunology, treatment, and prevention Notes from the field: hantavirus pulmonary syndrome-Maine Hantavirus pulmonary syndrome Global warming and epidemic trends of an emerging viral disease in Western-Europe: the Nephropathia epidemica case.


id: cord-336909-nnxa5ant
author: Guedez-López, Gladys Virginia
date: 2020-08-17
extension: .txt
mime: text/plain
words: 3250
sentence: 113
flesch: 43
cache: cache/cord-336909-nnxa5ant.txt
txt: txt/cord-336909-nnxa5ant.txt
title:
  Evaluation of three immunochromatographic tests for rapid detection of antibodies against SARS-CoV-2

summary:
  Considering the high rate of false positives when using Prometheus® test, an extra 20 serum samples of randomly selected patients from 2018 were studied as negative controls and the results confirmed a high percentage of false positive with this assay (35%). Regarding the In addition, 20 extra serum samples of randomly selected patients from 2018 were tested as negative control with Prometheus® and Sienna® test.


id: cord-006450-si5168pb
author: Jouneau, S.
title: Which patients should be tested for viruses on bronchoalveolar lavage fluid?
date: 2012-12-14
extension: .txt
mime: text/plain
words: 3121
sentence: 122
flesch: 32
cache: cache/cord-006450-si5168pb.txt
txt: txt/cord-006450-si5168pb.txt
summary:
  To better inform the use of viral tests in patients with respiratory diseases, we performed an observational, retrospective study in our institution, with three aims: (i) to assess the diagnostic value of viral tests on BALF in routine practice; (ii) to analyze the characteristics of patients with virus-positive BALF; and (iii) to identify the factors predictive of positive viral tests in BALF. The variables associated with positive viral tests on univariate analysis were immunosuppression [human immunodeficiency virus (HIV), corticosteroids >10 mg/day for ≥3 weeks, or other immunosuppressive therapy], ground-glass attenuations on computed tomography (CT) scanning, late-onset ventilator-associated pneumonia (VAP), and durations of (i) hospital stay, (ii) intensive care unit (ICU) stay, and (iii) mechanical ventilation before BAL (p < 0.01 for each comparison).


id: cord-004967-4523cwwi
author: Hsueh, P.-R.
date: 2013-10-18
extension: .txt
mime: text/plain
words: 3255
sentence: 123
flesch: 41
cache: cache/cord-004967-4523cwwi.txt
txt: txt/cord-004967-4523cwwi.txt
title:
  Bacteria killing nanotechnology Bio-Kil effectively reduces bacterial burden in intensive care units

summary:
  Hospital infection control: recent progress and opportunities under prospective payment The financial incentive for hospitals to prevent nosocomial infections under the prospective payment system. Relevant studies have shown that surfaces in the rooms of hospitalized patients who have been infected with or colonized by methicillin-resistant Staphylococcus aureus (MRSA) or vancomycin-resistant enterococci (VRE) are more likely to be contaminated with these bacteria than surfaces in rooms housing patients without MRSA or VRE infection


id: cord-005057-deq5tv1d
author: Bergström, T.
date: 1990
extension: .txt
mime: text/plain
words: 3492
sentence: 117
flesch: 40
cache: cache/cord-005057-deq5tv1d.txt
txt: txt/cord-005057-deq5tv1d.txt
title:
  Neurovirulence of herpes simplex virus types 1 and 2 isolates in diseases of the central nervous system

summary:
  HSV-1 encephalitis strains were significantly more virulent after nose inoculation (i.e. neuroinvasive) when compared with HSV-1 isolates from patients with oral lesions only, whereas HSV-2 meningitis strains were significantly more virulent after i.c. inoculation when compared with HSV-2 isolates from patients with genital lesions only. HSV-1 encephalitis strains were significantly more virulent after nose inoculation (i.e. neuroinvasive) when compared with HSV-1 isolates from patients with oral lesions only, whereas HSV-2 meningitis strains were significantly more virulent after i.c. inoculation when compared with HSV-2 isolates from patients with genital lesions only.


id: cord-286749-si83t03j
author: Lu, Q.-B.
date: 2014-07-29
extension: .txt
mime: text/plain
words: 3318
sentence: 142
flesch: 42
cache: cache/cord-286749-si83t03j.txt
txt: txt/cord-286749-si83t03j.txt
title:
  Epidemic and molecular evolution of human bocavirus in hospitalized children with acute respiratory tract infection

summary:
  Logistic regression models were used to explore the factors associated with higher HBoV-1 detection and to determine the association between clinical characteristics and HBoV-1 infection, with clinical disease as the dependent variable and HBoV-1 infection as the independent variable. In conclusion, our study disclosed the epidemiological and genetic dynamics of HBoV-1 epidemics in southeastern China in the most recent 3 years, the information of which might help to further improve our understanding of HBoV-1 infection and guide better surveillance and control strategies in the future.


id: cord-006561-w4s0k75p
author: Fink, D.
title: Blood culture fluorescence rates predict severity and mortality of invasive pneumococcal pneumonia
date: 2015-05-02
extension: .txt
mime: text/plain
words: 3379
sentence: 142
flesch: 36
cache: cache/cord-006561-w4s0k75p.txt
txt: txt/cord-006561-w4s0k75p.txt
summary:
  In contrast, there are increasing data that correlate pneumococcal bacterial load measured by molecular assays with clinical outcome [20, 21] : detection of high bacterial load has specificity exceeding 80 % for septic shock and mechanical ventilation Patients receiving antimicrobial therapy prior to blood cultures were excluded from the study.


id: cord-267533-nmgtan4e
author: Hu, Zhigang
date: 2020-10-29
extension: .txt
mime: text/plain
words: 3608
sentence: 152
flesch: 39
cache: cache/cord-267533-nmgtan4e.txt
txt: txt/cord-267533-nmgtan4e.txt
title:
  Delayed hospital admission and high-dose corticosteroids potentially prolong SARS-CoV-2 RNA detection duration of patients with COVID-19

summary:
  By shrinking down to zero coefficient weights, LASSO regression analysis has the ability to eliminate exposures that are non-related to the outcome [9, 11] . In the first step of our study, we identified the independent risk factors of long-term positive SARS-CoV-2 RNA detection by using LASSO logistic regression analysis and SARS-CoV-2 RNA detection duration by using LASSO Cox regression analysis.


id: cord-275561-9f1las3y
author: Wielders, C. C. H.
date: 2015-01-11
extension: .txt
mime: text/plain
words: 3895
sentence: 147
flesch: 40
cache: cache/cord-275561-9f1las3y.txt
txt: txt/cord-275561-9f1las3y.txt
title:
  Single nucleotide polymorphisms in immune response genes in acute Q fever cases with differences in self-reported symptoms

summary:
  There is a less clear distinction between the genotypes and symptom score compared to population 1 (Fig. 1) , i.e., all genotypes show moderate to high symptom scores. Higher symptom severity in population 2 could possibly be explained by higher environmental exposure dose, as reflected by the large numbers of abortions in goats in the 2009 outbreak and extremely high attack rates in farm contacts [14] .


id: cord-006766-u31go6xi
author: Lepur, D.
date: 2011-01-29
extension: .txt
mime: text/plain
words: 3922
sentence: 189
flesch: 43
cache: cache/cord-006766-u31go6xi.txt
txt: txt/cord-006766-u31go6xi.txt
title:
  Prospective observational cohort study of cerebrovascular CO(2) reactivity in patients with inflammatory CNS diseases

summary:
  The most prominent difference between BM and NBM patients was the difference in the level of consciousness disturbance (GCS): BM patients had worse scores (GCS 8 vs. 11.5). key: cord-006766-u31go6xi authors: Lepur, D.; Kutleša, M.; Baršić, B. title: Prospective observational cohort study of cerebrovascular CO(2) reactivity in patients with inflammatory CNS diseases date: 2011-01-29 journal: Eur J Clin Microbiol Infect Dis DOI: 10.1007/s10096-011-1184-3 sha: doc_id: 6766 cord_uid: u31go6xi The purpose of this study was to evaluate the significance of cerebrovascular CO(2) reactivity (CO(2) R) in the course and outcome of inflammatory central nervous system (CNS) diseases.


id: cord-025861-nsrs6dmc
author: Waldeck, Frederike
date: 2020-06-03
extension: .txt
mime: text/plain
words: 3993
sentence: 203
flesch: 40
cache: cache/cord-025861-nsrs6dmc.txt
txt: txt/cord-025861-nsrs6dmc.txt
title:
  Influenza-associated aspergillosis in critically-ill patients—a retrospective bicentric cohort study

summary:
  Organ supportive therapies and complications were more frequent in IAA patients than in non-IAA patients ( Table 2 in the Appendix). The length of stay in the ICU was significantly elevated in IAA patients (Fig. 2) .


id: cord-006517-845w9r6l
author: Lalueza, A.
date: 2017-05-13
extension: .txt
mime: text/plain
words: 4071
sentence: 174
flesch: 41
cache: cache/cord-006517-845w9r6l.txt
txt: txt/cord-006517-845w9r6l.txt
title:
  Impact of severe hematological abnormalities in the outcome of hospitalized patients with influenza virus infection

summary:
  Although hematological abnormalities have been described among patients with influenza virus infection, little is known about their impact on the outcome of the patients. This was an observational retrospective study including all adult patients with diagnosis of influenza virus infection hospitalized from January to May 2016 in our institution.


id: cord-010959-sigw7yxk
author: Lampejo, Temi
title: Influenza and antiviral resistance: an overview
date: 2020-02-13
extension: .txt
mime: text/plain
words: 4498
sentence: 162
flesch: 33
cache: cache/cord-010959-sigw7yxk.txt
txt: txt/cord-010959-sigw7yxk.txt
summary:
  21 Continued emergence and changing epidemiology of oseltamivir-resistant influenza A(H1N1)2009 virus, United Kingdom, winter 2010/11 A(H1N1) influenza viruses in Japan during the 2008-2009 season Clinical implications of antiviral resistance in influenza Oseltamivir resistance-disabling our influenza defenses Global update on the susceptibility of human influenza viruses to neuraminidase inhibitors Evaluation of intravenous peramivir for treatment of influenza in hospitalized patients Systematic review of influenza resistance to the neuraminidase inhibitors Structural and functional basis of resistance to neuraminidase inhibitors of influenza B viruses The potential impact of neuraminidase inhibitor resistant influenza Mutations of neuraminidase implicated in neuraminidase inhibitors resistance Recovery of drug-resistant influenza virus from immunocompromised patients: a case series Surveillance and Laboratory Testing of influenza Neuraminidase Inhibitor Five years of monitoring for the emergence of oseltamivir resistance in patients with influenza a infections in the influenza resistance information study. This article discusses these issues including novel agents and experimental strategies that have been used in an attempt to treat as well as prevent the emergence of resistant influenza viruses in humans.


id: cord-006308-s5le8ugm
author: Dimopoulos, G.
date: 2007-05-25
extension: .txt
mime: text/plain
words: 4722
sentence: 199
flesch: 42
cache: cache/cord-006308-s5le8ugm.txt
txt: txt/cord-006308-s5le8ugm.txt
title:
  Candidemia in immunocompromised and immunocompetent critically ill patients: a prospective comparative study

summary:
  Oropharyngeal candidiasis was detected in 5 of 9 (55.5%) IC patients and in 1 of 15 (6.5%) NIC patients (p = 0.015). Oropharyngeal candidiasis was detected in 5 of 9 (55.5%) IC patients and in 1 of 15 (6.5%) NIC patients (p= 0.015).


id: cord-272943-q09i8fqu
author: Dalhoff, A.
date: 2014-12-17
extension: .txt
mime: text/plain
words: 4721
sentence: 214
flesch: 33
cache: cache/cord-272943-q09i8fqu.txt
txt: txt/cord-272943-q09i8fqu.txt
title:
  Antiviral, antifungal, and antiparasitic activities of fluoroquinolones optimized for treatment of bacterial infections: a puzzling paradox or a logical consequence of their mode of action?

summary:
  Although the complexity and diversity of prokaryotic and eukaryotic topoisomerases is remarkable and little or no sequence homology of amino acids exists, type I and type II topoisomerases share certain structural elements mediating identical functions like DNA relaxation or DNA transport in bacteria, DNA viruses, yeasts, and parasites; the DNA helicase coordinates the directionality of topoisomerase activity; RNA helicases as present, e.g., in hepatitis C virus (HCV) directly interact with double-stranded DNA or RNA and assembles complexes with type II topoisomerases [49] [69] inhibited viral topoisomerase activity of vaccinia virus but not of herpes simplex virus and influenza virus


id: cord-028379-ghudhac6
author: Eichenberger, Emily M.
date: 2020-07-04
extension: .txt
mime: text/plain
words: 5469
sentence: 227
flesch: 45
cache: cache/cord-028379-ghudhac6.txt
txt: txt/cord-028379-ghudhac6.txt
title:
  Complement levels in patients with bloodstream infection due to Staphylococcus aureus or Gram-negative bacteria

summary:
  The horizontal lines compare medians across groups SAB patients as compared to community controls. We present complement levels in Staphylococcus aureus bacteremia (SAB) and Gram-negative bacteremia (GNB) and describe observed associations of complement levels with clinical outcomes.


id: cord-283399-iz4l9i0d
author: O’Gorman, C.
title: Human metapneumovirus in adults: a short case series
date: 2006-03-14
extension: .txt
mime: text/plain
words: 1486
sentence: 69
flesch: 38
cache: cache/cord-283399-iz4l9i0d.txt
txt: txt/cord-283399-iz4l9i0d.txt
summary:
  It is clear that respiratory viruses are the principal pathogens in a proportion of such cases [4] . The routine assay used to detect respiratory viruses in the regional virus laboratory is a multiplex, nested RT-PCR for 12 common respiratory pathogens: influenza A (H3 and H1) and B; parainfluenza virus types 1, 2 and 3; respiratory syncytial virus A and B; adenovirus; human rhinovirus; coronavirus 229E; and hMPV.


id: cord-285757-fiqx4tll
author: Mäkelä, M. J.
date: 1999
extension: .txt
mime: text/plain
words: 1826
sentence: 79
flesch: 46
cache: cache/cord-285757-fiqx4tll.txt
txt: txt/cord-285757-fiqx4tll.txt
title:
  Lack of Induction by Rhinoviruses of Systemic Type I Interferon Production or Enhanced MxA Protein Expression During the Common Cold

summary:
  285757 cord_uid: fiqx4tll To study whether MxA protein expression is systemically upregulated during rhinovirus infection, blood specimens were collected from 40 patients with common cold and MxA expression in mononuclear cells analyzed by flow cytometry. Although we did not find IFN or clearly induced MxA protein expression in the peripheral blood of any subject with rhinovirus infection, we cannot rule out the possibly significant role of IFN in local epithelial response against the virus.


id: cord-323476-rb9n5wc0
author: Poole, Stephen
date: 2020-09-09
extension: .txt
mime: text/plain
words: 1909
sentence: 89
flesch: 43
cache: cache/cord-323476-rb9n5wc0.txt
txt: txt/cord-323476-rb9n5wc0.txt
title:
  How are rapid diagnostic tests for infectious diseases used in clinical practice: a global survey by the International Society of Antimicrobial Chemotherapy (ISAC)

summary:
  key: cord-323476-rb9n5wc0 authors: Poole, Stephen; Townsend, Jennifer; Wertheim, Heiman; Kidd, Stephen P.; Welte, Tobias; Schuetz, Philipp; Luyt, Charles-Edouard; Beishuizen, Albertus; Jensen, Jens-Ulrik Stæhr; del Castillo, Juan González; Plebani, Mario; Saeed, Kordo title: How are rapid diagnostic tests for infectious diseases used in clinical practice: a global survey by the International Society of Antimicrobial Chemotherapy (ISAC) date: 2020-09-09 journal: Eur J Clin Microbiol Infect Dis DOI: 10.1007/s10096-020-04031-2 sha: doc_id: 323476 cord_uid: rb9n5wc0 Novel rapid diagnostic tests (RDTs) offer huge potential to optimise clinical care and improve patient outcomes. Rapid diagnostic tests (RDTs) are increasingly used in clinical practice to provide actionable information for patient care in a timely manner, ideally at the time and location of the patient's interaction with health care systems.


id: cord-346726-u7dhbmht
author: Keske, Şiran
date: 2018-01-13
extension: .txt
mime: text/plain
words: 2207
sentence: 95
flesch: 35
cache: cache/cord-346726-u7dhbmht.txt
txt: txt/cord-346726-u7dhbmht.txt
title:
  The rapid diagnosis of viral respiratory tract infections and its impact on antimicrobial stewardship programs

summary:
  Case definitions for influenza surveillance Prevalence and seasonal distribution of respiratory viruses during the 2014-2015 season in Istanbul Evaluating the impact of the multiplex respiratory virus panel polymerase chain reaction test on the clinical management of suspected respiratory viral infections in adult patients in a hospital setting Clinical diagnosis, viral PCR, and antibiotic utilization in community-acquired pneumonia Antibiotic discontinuation rates associated with positive respiratory viral panel and low procalcitonin results in proven or suspected respiratory infections The clinical impact of the detection of potential etiologic pathogens of community-acquired pneumonia Serum procalcitonin measurement and viral testing to guide antibiotic use for respiratory infections in hospitalized adults: a randomized controlled trial Routine molecular point-of-care testing for respiratory viruses in adults presenting to hospital with acute respiratory illness (ResPOC): a pragmatic, open-label, randomised controlled trial Mean duration of inappropriate antibiotic use (days) 6.5 (SD 3.1) 4.6 (SD 2.0) < 0.001 9.7 (SD 7.3) 6.2 (SD 3.7) 0.007 Rates of hospitalizations for respiratory syncytial virus, human metapneumovirus, and influenza virus in older adults ECIL-4): guidelines for diagnosis and treatment of human respiratory syncytial virus, parainfluenza virus, metapneumovirus, rhinovirus, and coronavirus Community-acquired pneumonia requiring hospitalization among U.S. adults Role of influenza and other respiratory viruses in admissions of adults to Canadian hospitals Antibiotic use for viral acute respiratory tract infections remains common Ambulatory antibiotic prescribing for acute bronchitis and cough and hospital admissions for respiratory infections: time trends analysis Antibiotic prescription rates for acute respiratory tract infections in US ambulatory settings Prevalence of inappropriate antibiotic prescriptions among US ambulatory care visits Implementing an antibiotic stewardship program: guidelines by the Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Statement: guidelines for reporting observational studies World Health Organization (WHO) (2014) WHO surveillance case definitions for ILI and SARI.


id: cord-349562-ivu632j2
author: Hernes, S. S.
date: 2010-09-18
extension: .txt
mime: text/plain
words: 3366
sentence: 141
flesch: 49
cache: cache/cord-349562-ivu632j2.txt
txt: txt/cord-349562-ivu632j2.txt
title:
  Swabbing for respiratory viral infections in older patients: a comparison of rayon and nylon flocked swabs

summary:
  An outbreak of severe respiratory tract infection due to human metapneumovirus in a long-term care facility Respiratory syncytial virus infection in elderly and highrisk adults Respiratory syncytial virus pneumonia among the elderly: an assessment of disease burden A summer outbreak of human metapneumovirus infection in a long-term-care facility Mortality associated with influenza and respiratory syncytial virus in the United States Is clinical recognition of respiratory syncytial virus infection in hospitalized elderly and high-risk adults possible? Evaluation of four methods for the diagnosis of respiratory syncytial virus infection in older adults Lack of sensitivity of rapid antigen tests for the diagnosis of respiratory syncytial virus infection in adults Rapid molecular detection of influenza outbreaks in nursing homes Viral pneumonia in older adults A simple and reproducible method for collecting nasal secretions in frail elderly adults, for measurement of virus-specific IgA Respiratory viruses and influenza-like illness: a survey in the area of Rome Comparison of flocked and rayon swabs for collection of respiratory epithelial cells from uninfected volunteers and symptomatic patients Comparison of nasopharyngeal flocked swabs and aspirates for rapid diagnosis of respiratory viruses in children Comparison of respiratory virus detection rates for infants and toddlers by use of flocked swabs, saline aspirates, and saline aspirates mixed in universal transport medium for room temperature storage and shipping Identification of respiratory viruses in adults: nasopharyngeal versus oropharyngeal sampling Comparison of nasopharyngeal aspirate and nasopharyngeal swab specimens for respiratory syncytial virus diagnosis by cell culture, indirect immunofluorescence assay, and enzymelinked immunosorbent assay Comparison between pernasal flocked swabs and nasopharyngeal aspirates for detection of common respiratory viruses in samples from children Nasal swab versus nasopharyngeal aspirate for isolation of respiratory viruses Surveillance of respiratory virus infections in adult hospital admissions using rapid methods Development of a genomics-based PCR assay for detection of Mycoplasma pneumoniae in a large outbreak in New York State Evaluation of real-time quantitative PCR for identification and quantification of Chlamydia pneumoniae by comparison with immunohistochemistry The use of TaqMan PCR assay for detection of Bordetella pertussis infection from clinical specimens Real-time quantitative PCR assays for detection and monitoring of pathogenic human viruses in immunosuppressed pediatric patients Clinical diagnosis of influenza virus infection: evaluation of diagnostic tools in general practice Increased detection of respiratory syncytial virus, influenza viruses, parainfluenza viruses, and adenoviruses with real-time PCR in samples from patients with respiratory symptoms Comparison of real-time PCR assays with fluorescent-antibody assays for diagnosis of respiratory virus infections in children Rapid and sensitive method using multiplex real-time PCR for diagnosis of infections by influenza A and influenza B viruses, respiratory syncytial virus, and parainfluenza viruses 1, 2, 3, and 4 Real-time reverse transcriptase PCR assay for detection of human metapneumoviruses from all known genetic lineages Acknowledgements


id: cord-274567-xd37wxxf
author: Monpoeho, S.
date: 2002-07-13
extension: .txt
mime: text/plain
words: 3286
sentence: 128
flesch: 42
cache: cache/cord-274567-xd37wxxf.txt
txt: txt/cord-274567-xd37wxxf.txt
title:
  Application of a Real-Time Polymerase Chain Reaction with Internal Positive Control for Detection and Quantification of Enterovirus in Cerebrospinal Fluid

summary:
  The variability observed with 50 copies of EV RNA standard was acceptable, and the detection limit of the RT-PCR is therefore 50 copies of EV RNA standard per reaction. Only duration of hospitalization showed a statistically significant decrease from 2.7 days for patients with negative PCR results to 1.8 days for patients with positive PCR results (P=0.042).


id: cord-355450-v3eh1rtk
author: Boattini, Matteo
title: Influenza and respiratory syncytial virus infections in the oldest-old continent
date: 2020-06-27
extension: .txt
mime: text/plain
words: 2672
sentence: 98
flesch: 36
cache: cache/cord-355450-v3eh1rtk.txt
txt: txt/cord-355450-v3eh1rtk.txt
summary:
  Analysis of acute respiratory infections due to influenza virus A, B and RSV during an influenza epidemic Predictors of mortality of influenza virus infections in a Swiss Hospital during four influenza seasons: role of quick sequential organ failure assessment Postpandemic influenza A/H1N1pdm09 is associated with more severe outcomes than A/H3N2 and other respiratory viruses in adult hospitalisations Clinical characteristics of influenzaassociated pneumonia of adults: clinical features and factors contributing to severity and mortality Clinical and radiographic comparison of influenza virusassociated pneumonia among three viral subtypes Intensive care admissions and associated severity of influenza B versus a during influenza B vaccinemismatched seasons Comparative outcomes of adults hospitalized with seasonal influenza A or B virus infection: application of the 7-category ordinal scale Outcomes and prognostic features of patients with influenza requiring hospitalization and receiving early antiviral therapy: a prospective multicenter cohort study High morbidity and mortality in adults hospitalized for respiratory syncytial virus infections The aging lung Critical care management of adults with community-acquired severe respiratory viral infection Rates of hospitalizations for respiratory syncytial virus, human metapneumovirus, and influenza virus in older adults Seasonal influenza activity during the SARS-CoV-2 outbreak in Japan Risk of mortality associated with respiratory syncytial virus and influenza infection in adults Official ERS/ATS clinical practice guidelines: noninvasive ventilation for acute respiratory failure Incubation periods of acute respiratory viral infections: a systematic review Avoiding hospital admission through provision of hospital care at home: a systematic review and meta-analysis of individual patient data Publisher's note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations Acknowledgments Similarly, in our population, NIV seemed to be effective since data about its use in respiratory viral infections are limited and uncertain, especially in the presence of pneumonia, hypoxemic respiratory failure, and SOFA ≥ 5, and no COPD and/or cardiogenic pulmonary edema [19] .


id: cord-321284-0y69n1ea
author: El Kholy, A. A.
date: 2016-06-10
extension: .txt
mime: text/plain
words: 3346
sentence: 145
flesch: 42
cache: cache/cord-321284-0y69n1ea.txt
txt: txt/cord-321284-0y69n1ea.txt
title:
  The use of multiplex PCR for the diagnosis of viral severe acute respiratory infection in children: a high rate of co-detection during the winter season

summary:
  The underrecognized burden of influenza in young children Respiratory syncytial virus and parainfluenza virus Progress in the development of respiratory syncytial virus and parainfluenza virus vaccines Practical implementation of a multiplex PCR for acute respiratory tract infections in children Influenza and other respiratory virus infections in outpatients with medically attended acute respiratory infection during the 2011-12 influenza season Performance of a novel microarray multiplex PCR for the detection of 23 respiratory pathogens (SYMP-ARI study) Does respiratory virus coinfection increases the clinical severity of acute respiratory infection among children infected with respiratory syncytial virus? Human bocavirus and acute wheezing in children Frequent detection of respiratory viruses without symptoms: toward defining clinically relevant cutoff values A case-control study of acute respiratory tract infection in general practice patients in the Netherlands Respiratory pathogens in children with and without respiratory symptoms Human bocavirus: a novel parvovirus epidemiologically associated with pneumonia requiring hospitalization in Thailand Detection of bocavirus in children suffering from acute respiratory tract infections in Saudi Arabia Antiviral strategies against human coronaviruses Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia Predominance of rhinovirus in the nose of symptomatic and asymptomatic infants Viruses and bacteria in the etiology of the common cold Rhinovirus illnesses during infancy predict subsequent childhood wheezing Role of respiratory viruses in acute upper and lower respiratory tract illness in the first year of life: a birth cohort study Highly frequent infections with human rhinovirus in healthy young children: a longitudinal cohort study The burden of respiratory syncytial virus infection in young children Influenza A and B virus infections in children Viral etiology of severe pneumonia among Kenyan infants and children Nucleic acids of respiratory viruses causing SARI were detected in 159/177 (89.9 %) patients enrolled in the study.


id: cord-271781-cfv0ta10
author: Patel, Kishan P.
title: Transmission of SARS-CoV-2: an update of current literature
date: 2020-07-07
extension: .txt
mime: text/plain
words: 4478
sentence: 169
flesch: 39
cache: cache/cord-271781-cfv0ta10.txt
txt: txt/cord-271781-cfv0ta10.txt
summary:
  Environmental contamination through airflow may perpetuate viral transmission through infectious droplets [25] . A study analyzing COVID-19 patients from three hospitals in China demonstrated higher positive rates of viral RNA in bronchoalveolar lavage fluid, sputum, and


id: cord-294551-s3nsiano
author: Muller, M. P.
title: Early diagnosis of SARS: lessons from the Toronto SARS outbreak
date: 2006-04-04
extension: .txt
mime: text/plain
words: 3639
sentence: 123
flesch: 40
cache: cache/cord-294551-s3nsiano.txt
txt: txt/cord-294551-s3nsiano.txt
summary:
  SARS patients without fever by the time of admission were older (76 vs. 44 years, p=0.001), had more comorbid illness (67 vs. 13%, p<0.0001), and were more likely to die from SARS (44 vs. 7%, p=0.045) than patients with fever. Because evidence suggests that Findings indicate percentage of laboratory results that were classified as above (ANC, CK, LDH) or below (WBC, ALC, PLT) the normal range the sensitivity and specificity of the case definitions used for SARS diagnosis may be limited [11, 12] and because inclusion of even small numbers of non-SARS cases within a cohort of SARS patients can limit the ability to recognize features unique to SARS, we focused our analysis on the confirmed patients.


id: cord-255785-wqlp6ogb
author: Liu, Wen-Kuan
date: 2019-09-05
extension: .txt
mime: text/plain
words: 4074
sentence: 164
flesch: 34
cache: cache/cord-255785-wqlp6ogb.txt
txt: txt/cord-255785-wqlp6ogb.txt
title:
  Paramyxoviruses respiratory syncytial virus, parainfluenza virus, and human metapneumovirus infection in pediatric hospitalized patients and climate correlation in a subtropical region of southern China: a 7-year survey

summary:
  Viral pneumonia Aetiological role of common respiratory viruses in acute lower respiratory infections in children under five years: a systematic review and meta-analysis Paramyxovirus infection: mortality and morbidity in a pediatric intensive care unit Epidemiological and clinical features of human metapneumovirus in hospitalised paediatric patients with acute respiratory illness: a cross-sectional study in southern China Respiratory syncytial virus-a comprehensive review Pathogenesis of acute respiratory illness caused by human parainfluenza viruses Viral infections of the lower respiratory tract: old viruses, new viruses, and the role of diagnosis The distinguishing features of human metapneumovirus and respiratory syncytial virus Prevalence of human respiratory syncytial virus circulating in Iran Epidemiological changes of respiratory syncytial virus (RSV) infections in Israel Epidemiology and clinical impact of parainfluenza virus infections in otherwise healthy infants and young children < 5 years old Epidemiology and clinical presentation of the four human parainfluenza virus types A newly discovered human pneumovirus isolated from young children with respiratory tract disease Virological features and clinical manifestations associated with human metapneumovirus: a new paramyxovirus responsible for acute respiratory-tract infections in all age groups Viral pneumonia in older adults Epidemiology of human metapneumovirus Nosocomial respiratory syncytial virus infections in the palivizumab-prophylaxis era with implications regarding high-risk infants Mortality and morbidity of nosocomial respiratory syncytial virus (RSV) infection in ventilated children-a ten year perspective Nosocomial transmission of respiratory syncytial virus in an outpatient cancer center Nosocomial RSV infection control and outbreak management Nosocomial respiratory viral infection Nosocomial transmission of parainfluenza 3 virus in hematological patients characterized by molecular epidemiology Molecular epidemiological investigation of a nosocomial outbreak of human metapneumovirus infection in a pediatric hemato-oncology patient population Palivizumab, a humanized respiratory syncytial virus monoclonal antibody, reduces hospitalization from respiratory syncytial virus infection in high-risk infants. 2005-2014 prospective study Children with respiratory disease associated with metapneumovirus in Hong Kong Human metapneumovirus associated with respiratory tract infections in a 3-year study of nasal swabs from infants in Italy Prevalence and clinical symptoms of human metapneumovirus infection in hospitalized patients Population-based surveillance for hospitalizations associated with respiratory syncytial virus, influenza virus, and parainfluenza viruses among young children Bronchiolitis-associated hospitalizations among US children Seasonal trends of human parainfluenza viral infections: United States The isolation of parainfluenza 4 subtypes A and B in England and serological studies of their prevalence Seasonal pattern in childhood viral lower respiratory tract infections in Melbourne Correlations between climate factors and incidence-a contributor to RSV seasonality Climatic factors and lower respiratory tract infection due to respiratory syncytial virus in hospitalised infants in northern Spain A four year seasonal survey of the relationship between outdoor climate and epidemiology of viral respiratory tract infections in a temperate climate Seasonal distribution and epidemiological characteristics of human metapneumovirus infections in pediatric inpatients in Southeast China Seasonal patterns of respiratory syncytial virus infection in Hong Kong: a preliminary report Incidence of common respiratory viral infections related to climate factors in hospitalized children in Hong Kong Acknowledgments We thank the study volunteers for their generous participation.


id: cord-344017-qldawc8m
author: Edouard, S.
date: 2020-11-11
extension: .txt
mime: text/plain
words: 4022
sentence: 139
flesch: 40
cache: cache/cord-344017-qldawc8m.txt
txt: txt/cord-344017-qldawc8m.txt
title:
  Evaluating the serological status of COVID-19 patients using an indirect immunofluorescent assay, France

summary:
  We used it to assess the serological status of hundreds of COVID-19 patients and controls; as such, an assay has been only reported on a very small group of patients [14, 15] . key: cord-344017-qldawc8m authors: Edouard, S.; Colson, P.; Melenotte, C.; Di Pinto, F.; Thomas, L.; La Scola, B.; Million, M.; Tissot-Dupont, H.; Gautret, P.; Stein, A.; Brouqui, P.; Parola, P.; Lagier, J.-C.; Raoult, D.; Drancourt, Michel title: Evaluating the serological status of COVID-19 patients using an indirect immunofluorescent assay, France date: 2020-11-11 journal:


id: cord-350328-wu1ygt6w
author: Tambyah, P. A.
title: SARS: responding to an unknown virus
date: 2004-07-14
extension: .txt
mime: text/plain
words: 4862
sentence: 186
flesch: 49
cache: cache/cord-350328-wu1ygt6w.txt
txt: txt/cord-350328-wu1ygt6w.txt
summary:
  In our own hospital, the National University Hospital, the largest cluster of SARS cases occurred in one of our eight-bed wards [47] where patients are deliberately placed eight to a cubicle in order to support the philosophy of healthcare financing in Singapore. The Singapore experience [41] was that three flights with symptomatic SARS patients resulted in only one transmission.


id: cord-265729-prgj36g0
author: Lehtoranta, L.
title: Probiotics in respiratory virus infections
date: 2014-03-18
extension: .txt
mime: text/plain
words: 5040
sentence: 200
flesch: 28
cache: cache/cord-265729-prgj36g0.txt
txt: txt/cord-265729-prgj36g0.txt
summary:
  The economic burden of non-influenza-related viral respiratory tract infection in the United States Picornavirus and enterovirus diversity with associated human diseases Epidemiology and pathogenesis of influenza Epidemiology and prevention of respiratory syncytial virus infections among infants and young children Molecular evolution of human species D adenoviruses Respiratory viruses other than influenza virus: impact and therapeutic advances New respiratory viral infections Food and Agriculture Organization of the United Nations/World Health Organization (FAO/WHO) (2001) Health and nutritional properties of probiotics in food including powder milk with live lactic acid bacteria Guidance for substantiating the evidence for beneficial effects of probiotics: prevention and management of infections by probiotics Probiotics and health: an evidence-based review Antagonistic activities of lactobacilli and bifidobacteria against microbial pathogens Immunomodulatory effect of probiotic bacteria Probiotics as prevention and treatment for diarrhea Probiotics for preventing acute upper respiratory tract infections Effect of intranasal administration of Lactobacillus casei Shirota on influenza virus infection of upper respiratory tract in mice Reduction of influenza virus titer and protection against influenza virus infection in infant mice fed Lactobacillus casei shirota Oral administration of heat-killed Lactobacillus plantarum L-137 enhances protection against influenza virus infection by stimulation of type I interferon production in mice Efficacy of oral administration of heatkilled probiotics from Mongolian dairy products against influenza infection in mice: alleviation of influenza infection by its immunomodulatory activity through intestinal immunity Lactobacillus plantarum DK119 as a probiotic confers protection against influenza virus by modulating innate immunity Oral administration of lactobacilli from human intestinal tract protects mice against influenza virus infection Heat-killed Lactobacillus gasseri TMC0356 protects mice against influenza virus infection by stimulating gut and respiratory immune responses Effects of oral administration of yogurt fermented with Lactobacillus d e l b r u e c The purpose of this paper is to review the current knowledge on the effects of probiotics on respiratory virus infections and to provide insights on the possible antiviral mechanisms of probiotics.


id: cord-338070-y8zi8iz9
author: Liu, Wei
date: 2020-08-31
extension: .txt
mime: text/plain
words: 4129
sentence: 171
flesch: 43
cache: cache/cord-338070-y8zi8iz9.txt
txt: txt/cord-338070-y8zi8iz9.txt
title:
  Pharmacological inhibition of poly (ADP-ribose) polymerase by olaparib ameliorates influenza-virus-induced pneumonia in mice

summary:
  Olaparib remarkably reduced IAV mRNA expression, myeloperoxidase (MPO) level, and inflammatory cell infiltration in IAV lungs. Moreover, olaparib significantly reduced the level of interleukin (IL)-1β, tumor necrosis factor (TNF)-α, interferon (IFN)-γ, IL-6, and IL-4 and increased IL-10 in IAV lungs.


id: cord-350807-qdq96723
author: Reckziegel, Maria
date: 2020-05-27
extension: .txt
mime: text/plain
words: 4659
sentence: 207
flesch: 37
cache: cache/cord-350807-qdq96723.txt
txt: txt/cord-350807-qdq96723.txt
title:
  Viruses and atypical bacteria in the respiratory tract of immunocompromised and immunocompetent patients with airway infection

summary:
  Seminars in respiratory and critical care medicine Respiratory syncytial virus: infection, detection, and new options for prevention and treatment Human metapneumovirus infection after allogeneic hematopoietic stem cell transplantation Laboratory diagnosis of infections in cancer patients: challenges and opportunities Impact of viral multiplex real-time PCR on management of respiratory tract infection: a retrospective cohort study Burden of human metapneumovirus infections in patients with cancer: risk factors and outcomes Infection in organ transplantation Antiviral therapy for respiratory viral infections in immunocompromised patients Respiratory viral infections in solid organ and hematopoietic stem cell transplantation Treatment of alpha and beta herpesvirus infections in solid organ transplant recipients Herpesvirus respiratory infections in immunocompromised patients: epidemiology, management, and outcomes Multiple viral infections after haploidentical hematopoietic stem cell transplantation in a child with acute lymphoblastic leukemia Virus-bacteria interactions: an emerging topic in human infection Viral-bacterial co-infections in the respiratory tract Bacterial pneumonia as an influenza complication An official American Thoracic Society research statement: noninfectious lung injury after hematopoietic stem cell transplantation: idiopathic pneumonia syndrome Metagenomic sequencing detects respiratory pathogens in hematopoietic cellular transplant patients Effective use of oral ribavirin for respiratory syncytial viral infections in allogeneic haematopoietic stem cell transplant recipients Consecutive yearly outbreaks of respiratory syncytial virus in a haemato-oncology ward and efficacy of infection control measures Parainfluenza 3 infections early after kidney or simultaneous pancreas-kidney transplantation In vivo persistence of human rhinoviruses in immunosuppressed patients The Virome of the human respiratory tract Generation of multipotent cell lines from a distinct population of male germ line stem cells Lack of p73 mutations and late occurrence of p73 allelic deletions in melanoma tissues and cell lines Establishment of PCR for the early diagnosis of herpes simplex encephalitis HSV-2 DNA persistence in astrocytes of the trigeminal root entry zone: double labeling by in situ PCR and immunohistochemistry Detection of varicella-zoster virus DNA by polymerase chain reaction in the cerebrospinal fluid of patients suffering from neurological complications associated with chicken pox or herpes zoster Evaluation of the polymerase chain reaction for diagnosis of herpes simplex virus encephalitis Monitoring of patients for cytomegalovirus after organ transplantation by centrifugation culture and PCR Laboratory diagnosis of herpes zoster Detection of herpes simplex virus (types 1 and 2) and human herpesvirus 6 DNA in human brain tissue by polymerase chain reaction Detection by PCR of HHV-6 and EBV DNA in blood and oropharynx of healthy adults and HIV-seropositives Comparison of a LightCyclerbased real-time PCR for quantitation of Epstein-Barr viral load in different clinical specimens with semiquantitative PCR Human parechovirus infections in Dutch children and the association between serotype and disease severity Prevalence, types, and RNA concentrations of human parechoviruses, including a sixth parechovirus type, in stool samples from patients with acute enteritis Screening respiratory samples for detection of human rhinoviruses (HRVs) and enteroviruses: comprehensive VP4-VP2 typing reveals high incidence and genetic diversity of HRV species C MEGA6: molecular evolutionary genetics analysis version 6.0 Viruses as sole causative agents of severe acute respiratory tract infections in children Seroprevalence of herpes simplex virus type 1 and type 2 in Thuringia Seroprevalence of varicella-zoster virus in the German population Evolution of EBV seroprevalence and primary infection age in a French hospital and a city laboratory network Cytomegalovirus seroprevalence among children and adolescents in Germany: data from the German health interview and examination survey for children and adolescents (KiGGS) Human herpesvirus 6 Herpesvirus infections in organ transplant recipients Clinical impact of HSV-1 detection in the lower respiratory tract from hospitalized adult patients Quantitative detection of Epstein-Barr virus in bronchoalveolar lavage from transplant and nontransplant patients Detection of herpesvirus EBV DNA in the lower respiratory tract of ICU patients: a marker of infection of the lower respiratory tract? Epstein-Barr virus-associated pneumonia in patients with posttransplant lymphoproliferative disease after hematopoietic stem cell transplantation The role of infection in interstitial lung diseases: a review Epstein-Barr virus-associated pneumonia and bronchiolitis obliterans syndrome in a lung transplant recipient Detection of Epstein-Barr virus DNA in peripheral blood is associated with the development of bronchiolitis obliterans syndrome after lung transplantation Chromosomally integrated human herpesvirus 6: questions and answers Human herpesvirus-6 infections in kidney, liver, lung, and heart transplantation: review Varicella pneumonia in adults Detection of respiratory viruses using a multiplex real-time PCR assay in Germany Respiratory syncytial virus infection-associated hospitalization in adults: a retrospective cohort study Human bocaviruses: possible etiologic role in respiratory infection Human bocavirus infection as a cause of severe acute respiratory tract infection in children Frequent detection of bocavirus DNA in German children with respiratory tract infections Current understanding of human enterovirus D68 Enterovirus and parechovirus infection in children: a brief overview A method to identify respiratory virus infections in clinical samples using next-generation sequencing Capnetz Study G (2015)


id: cord-011417-a5q15dq1
author: Pace, David
title: The epidemiology of invasive meningococcal disease and the utility of vaccination in Malta
date: 2020-05-16
extension: .txt
mime: text/plain
words: 6689
sentence: 245
flesch: 43
cache: cache/cord-011417-a5q15dq1.txt
txt: txt/cord-011417-a5q15dq1.txt
summary:
  The Climate of Malta: statistics, trends and analysis 1951-2010 Environmental exposures and invasive meningococcal disease: an evaluation of effects on varying time scales The Stonehouse survey: nasopharyngeal carriage of meningococci and Neisseria lactamica United Kingdom meningococcal carriage group (2006) Social behavior and meningococcal carriage in British teenagers Meningococcal carriage among a university student population -United States Meningococcal carriage in Dutch adolescents and young adults; a cross-sectional and longitudinal cohort study Prevalence of meningococcal carriage in children and adolescents aged 10-19 years in Chile in 2013 Effectiveness and impact of a reduced infant schedule of 4CMenB vaccine against group B meningococcal disease in England: a national observational cohort study Seroprevalence of meningococcal serogroup C bactericidal antibody in England and Wales in the pre-vaccination era Invasive pneumococcal and meningococcal disease: association with influenza virus and respiratory syncytial virus activity? Meningococcal serogroup Y disease in Europe: continuation of high importance in some European regions in 2013 Cross-antigenicity and immunogenicity between capsular polysaccharides of group C Neisseria meningitidis and of Escherichia coli K92 Antigenic cross-reactivity between outer membrane proteins of Neisseria meningitidis and commensal Neisseria species B-cell responses to vaccination at the extremes of age Changes in Neisseria meningitidis disease epidemiology in the United States Significance of meningococcal hyperinvasive clonal complexes and their influence on vaccines development Genetic characterization of a new variant within the ET-37 complex of Neisseria meningitidis associated with outbreaks in various parts of the world Serogroup and clonal characterization of Czech invasive Neisseria meningitidis strains isolated from 1971 to Genotypic and phenotypic characterization of carriage and invasive disease isolates of Neisseria meningitidis in Finland Summary of product characteristics: Bexsero meningococcal group B vaccine for injection in prefilled syringe. The introduction of MenACWY and MenB vaccines on the national immunization schedule in Malta would be expected to reduce the disease burden of meningococcal disease in children and adolescents in Malta.


id: cord-314311-xbpb9nfi
author: Ge, Huipeng
title: The epidemiology and clinical information about COVID-19
date: 2020-04-14
extension: .txt
mime: text/plain
words: 5298
sentence: 256
flesch: 51
cache: cache/cord-314311-xbpb9nfi.txt
txt: txt/cord-314311-xbpb9nfi.txt
summary:
  Isolating virus from urine of the patient with novel coronavirus pneumonia Pattern of early human-to-human transmission of Wuhan Preliminary estimation of the basic reproduction number of novel coronavirus (2019-nCoV) in China, from 2019 to 2020: a datadriven analysis in the early phase of the outbreak Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China: a modelling study The reproductive number of COVID-19 is higher compared to SARS coronavirus An updated estimation of the risk of transmission of the novel coronavirus (2019-nCov) Middle East respiratory syndrome MERS coronavirus outbreak: implications for emerging viral infections MERS coronavirus induces apoptosis in kidney and lung by upregulating Smad7 and FGF2 First case of 2019 novel coronavirus in the United States CT imaging features of 2019 novel coronavirus (2019-nCoV). However, patients with SARS and MERS have more gastrointestinal involvement (about one-third) than COVID-19 patients [55] .


id: cord-348840-s8wjg4ar
author: Cobrado, L.
title: High-touch surfaces: microbial neighbours at hand
date: 2017-06-25
extension: .txt
mime: text/plain
words: 5843
sentence: 188
flesch: 17
cache: cache/cord-348840-s8wjg4ar.txt
txt: txt/cord-348840-s8wjg4ar.txt
summary:
  Microbial pathogens most frequently involved in the contamination of hospital environmental surfaces are (methicillinresistant) Staphylococcus aureus (MRSA), vancomycinresistant enterococci (VRE), Clostridium difficile, multidrug resistant Gramme-negative bacilli (such as Pseudomonas, Acinetobacter and Enterobacteriaceae), Norovirus, Coronavirus and Candida species [6] [7] [8] [9] [10] . The aim of this manuscript is to review the role of hightouch surfaces in healthcare-associated infections, from the aetiology to strategies for surface cleaning and addressing preventive trends.


id: cord-269726-z0frgm7s
author: Gidari, Anna
date: 2020-10-10
extension: .txt
mime: text/plain
words: 6714
sentence: 299
flesch: 47
cache: cache/cord-269726-z0frgm7s.txt
txt: txt/cord-269726-z0frgm7s.txt
title:
  Is recurrence possible in coronavirus disease 2019 (COVID-19)? Case series and systematic review of literature

summary:
  Long-term effects of COVID-19 in a patient on maintenance dialysis Glucocorticoid-induced relapse of COVID-19 in a patient with sarcoidosis Reevaluation of retested nucleic acid-positive cases in recovered COVID-19 patients: Report from a designated transfer hospital in Chongqing Recurrence of positive SARS-CoV-2 RNA in COVID-19: a case report Clinical recurrences of COVID-19 symptoms after recovery: viral relapse, reinfection or inflammatory rebound? Positive SARS-CoV-2 RNA recurs repeatedly in a case recovered from COVID-19: dynamic results from 108 days of follow-up Persistent SARS-COV-2 RNA positivity in a patient for 92 days after disease onset: a case report Positive conversion of COVID-19 after two consecutive negative RT-PCR results: a role of low-dose CT Recurrent presence of SARS-CoV-2 RNA in a 33-year-old man Repositive cases of nucleic acid tests in discharged patients with COVID-19: a follow-up study Positive SARS-Cov-2 test in a woman with COVID-19 at 22 days after hospital discharge: a case report Low humoral immune response and ineffective clearance of SARS-Cov-2 in a COVID-19 patient with CLL during a 69-day follow-up Recurrent positive nucleic acid detection in a recovered COVID-19 patient: a case report and literature review Successful recovery of recurrence of positive SARS-CoV-2 RNA in COVID-19 patient with systemic lupus erythematosus: a case report and review Clinical characteristics of severe acute respiratory syndrome coronavirus 2 reactivation Absent immune response to SARS-CoV-2 in a 3-month recurrence of coronavirus disease 2019 (COVID-19) case Recurrence of SARS-CoV-2 infection with a more severe case after mild COVID-19, reversion of RT-qPCR for positive and late antibody response: case report Repeated COVID-19 relapse during post-discharge surveillance with viral shedding lasting for 67 days in a recovered patient infected with SARS-CoV-2 COVID-19 infection recurrence presenting with meningoencephalitis Post discharge positive re-tests in COVID-19: common but clinically non-significant Progressive CT findings and positive RT-PCR again of recovered and discharged patients with COVID-19 Changes in RT-PCR test results and symptoms during the menstrual cycle of female individuals infected with SARS-CoV-2: report of two cases Incidence, clinical course and risk factor for recurrent PCR positivity in discharged COVID-19 patients in Guangzhou, China: a prospective cohort study COVID-19 re-infection by a phylogenetically distinct SARS-coronavirus-2 strain confirmed by whole genome sequencing The treatment and follow-up of 'recurrence' with discharged COVID-19 patients: data from Guizhou Recurrent recurrence of positive SARS-CoV-2 RNA in a COVID-19 patient Recurrence or relapse of COVID-19 in older patients: a description of three cases Recurrent pneumonia in a patient with new coronavirus infection after discharge from hospital for insufficient antibody production: a case report A case presentation for positive SARS-CoV-2 RNA recurrence in a patient with a history of type 2 diabetes that had recovered from severe COVID-19 Clinical features of discharged COVID-19 patients with an extended SARS-CoV-2 RNA positive signal in respiratory samples The dilemma of COVID-19 recurrence after clinical recovery Persistent positivity and fluctuations of SARS-CoV-2 RNA in clinically-recovered COVID-19 patients Probable causes and risk factors for positive SARS-CoV-2 test in recovered patients: evidence from Brunei Darussalam Epidemiological characteristics of COVID-19 patients in convalescence period Chest CT study of fifteen COVID-19 patients with positive RT-PCR retest results after discharge Rate of re-positive RT-PCR test among patients recovered from COVID-19 Discontinuation of antiviral drugs may be the reason for recovered COVID-19 patients testing positive again Changes in serum virus-specific IgM/IgG antibody in asymptomatic and discharged patients with reoccurring positive COVID-19 nucleic acid test (RPNAT) Chest CT and clinical follow-up of discharged patients with COVID-19 in Wenzhou City A cluster of the Corona Virus Disease 2019 caused by incubation period transmission in Wuxi Re-positive coronavirus disease 2019 PCR test: could it be a reinfection? Diagnostic testing and screening for SARS-CoV-2 Growth kinetics of SARS-coronavirus in Vero E6 cells Detection and isolation of SARS-CoV-2 in serum, urine, and stool specimens of COVID-19 patients from the Republic of Korea Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement Positive result of Sars-Cov-2 in faeces and sputum from discharged patient with COVID-19 in Yiwu Song S Recurrence of positive SARS-CoV-2 viral RNA in recovered COVID-19 patients during medical isolation observation Positive RT-PCR test results in discharged COVID-19 patients: reinfection or residual Coronavirus disease (COVID-19) in a paucisymptomatic patient: Epidemiological and clinical challenge in settings with limited community transmission Seven discharged patients turning positive again for SARS-CoV-2 on quantitative RT-PCR Serial CT features in discharged COVID-19 patients with positive RT-PCR re-test A case series of recurrent viral RNA positivity in recovered COVID-19 Chinese patients The clinical features and outcomes of discharged coronavirus disease 2019 patients: a prospective cohort study Re-infection by COVID-19: a real threat for the future management of pandemia? Letter to the Editor: Three cases of re-detectable positive SARS-CoV-2 RNA in recovered COVID-19 Microbiol Infect Dis patients with antibodies Two cases of COVID-19 with positive salivary and negative pharyngeal or respiratory swabs at hospital discharge: a rising concern Persistent viral RNA positivity during recovery period of a patient with SARS-CoV-2 infection Recurrent PCR positivity after hospital discharge of people with coronavirus disease 2019 (COVID-19) Rehospitalization of a recovered coronavirus disease 19 (COVID-19) child with positive nucleic acid detection


id: cord-325238-2nhade3s
author: Seleem, Noura M.
date: 2020-04-23
extension: .txt
mime: text/plain
words: 8515
sentence: 391
flesch: 46
cache: cache/cord-325238-2nhade3s.txt
txt: txt/cord-325238-2nhade3s.txt
title:
  Drugs with new lease of life as quorum sensing inhibitors: for combating MDR Acinetobacter baumannii infections

summary:
  In the present study, QSIs markedly reduced biofilm formation in A. baumannii clinical isolates as 50% inhibition was observed in 75% of A. baumannii isolates. Assay of biofilm formation, twitching motility, sensitivity to oxidative stress and protease, and gelatinase activity were performed for both P. aeruginosa (PAO1) and A. baumannii isolates.


