id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
eurjchem-1125	Gouda, Moustafa Ahmed; El Bialy, Serry Atta Atta	Synthesis and antioxidant evaluation of novel sophisticated carboxamides based on 3-(ethoxycarbonyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-amine	2014	8	.pdf	application/pdf	5418	291	66	Attempting for preparation of compounds 21 and 22, which were bioisostere of compound 16 via reaction of compound 3 with phenyl isothiocyanate in dry DMF in the presence of potassium hydroxide followed by addition of reaction with chloroacetone or ethyl bromoacetate was failed. Reaction of ethyl‐2‐[({2‐[(cyanoacetyl)amino]‐4,5,6,7‐ tetrahydrobenzo[b]thien‐3‐yl}carbonyl)amino]‐4,5,6,7‐tetra hydro‐1‐benzothiophene‐3‐carboxylate (7) with aromatic aldehydes General procedure: A mixture of compound 7 (1.17 g, 2.5 mmol), 4‐(dimethylamino) benzaldehyde (0.37 g, 2.5 mmol), 4‐ (piperidin‐1‐yl)benzaldehyde (0.47g, 2.5 mmol), or 2‐hydroxy benzaldehyde (0.31 g, 2.5 mmol) in ethanol (15 mL) containing piperidine (0.2 mL) was stirred at 80 °C for 4 h.	cache/eurjchem-1125.pdf	txt/eurjchem-1125.txt